Copine-3

Overview
NameCopine-3
Smed IDSMED30009900
Length (bp)2163
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Copine-3 (SMED30009900) t-SNE clustered cells

Violin plots show distribution of expression levels for Copine-3 (SMED30009900) in cells (dots) of each of the 12 neoblast clusters.

 

back to top


 

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Copine-3 (SMED30009900) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Copine-3 (SMED30009900) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

back to top


 

Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

back to top
Anatomical Expression

PAGE et. al., 2020




SMED30009900

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 8

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
head regionSMED30009900h1SMcG0010123 SmedASXL_011441SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016
whole organism asexual adult RNA-sequencing evidence
nervous systemSMED30009900h1SMcG0010123 dd_Smed_v4_15889_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30009900h1SMcG0010123 dd_Smed_v4_15889_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neuronSMED30009900h1SMcG0010123 dd_Smed_v4_15889_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
whole organism asexual adult colorimetric in situ hybridization evidence
non-ciliated neuronSMED30009900h1SMcG0010123 dd_Smed_v4_15889_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
head regionSMED30009900h1SMcG0010123 dd_Smed_v6_15889_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017
whole organism asexual adult RNA-sequencing evidence
reproductive organSMED30009900h1SMcG0010123 Contig43308uc_Smed_v2PMID:28434803
Rouhana et al., 2017
whole organism adult hermaphrodite RNA-sequencing evidence
reproductive organSMED30009900h1SMcG0010123 Contig43308newmark_estsPMID:28434803
Rouhana et al., 2017
whole organism adult hermaphrodite RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
BLAST of Copine-3 vs. Ensembl Human
Match: CPNE8 (copine 8 [Source:HGNC Symbol;Acc:HGNC:23498])

HSP 1 Score: 320.087 bits (819), Expect = 6.301e-100
Identity = 194/490 (39.59%), Postives = 289/490 (58.98%), Query Frame = 1
Query:  358 FDAKLCIEYLFEEKQMIIIEIFEYDITQDGDNL-----LGEVDCSIGRVIHSGGVVLKPLEITDEFKTTLGPLSPEVGIYV---EEDLTAKENIELKIRGIGLAKTEIFGKTDPYLMIFRCNNRSRYVQCYRTEVLKNTQNPDWSPIVVSYERLCNNDLNSVLCLRVYCGDGTLKESEEVDIACDQLVGEIKVTARELIQMRRMEEKQFELINPXXXXXXXSYLNSGIISVRAQKTNSEPTFLDFMFQGLELNFIVAIDLTLSNGDSSLPSSLHFMDCSLTNEYSVAIQAVLEILQEYDNDELFPAFGFGARVPPDYKICHEYPLNGDFENPYCRGAEGVIHAYQQTLKEVKLAGPTCFSPVIRHISRLAKASESGKHYFVLLILTDGSVDDWVETKKAVVETSYLPXXXXXXXXXXXKFSDMETLDQDFGLLMVSNEKACRDNVQFVKMRRYLRVAADGSDNIRWSKVALAKDVLAELPYQVNEYMHRK 1803
            F  K  ++Y FEE++ +  ++  YD+     NL     LG+V C++G ++ S G  L+        K  +G    + G  +   EE    ++ + ++     L K + FGK+DP+L+ +R N    +  C++TEV+KNT NP W    +S   LCN D +  + + VY  D                +GE   + REL + +  +   +E++NPKKK KKK Y NSG +++ +    +E +FLD++  G ++NF VAID T SNG+ + P+SLH+M+    N Y +A++AV EI+Q+YD+D++FPA GFGA++PPD +I HE+ LNG+ +NPYC G EGV+ AY ++LK V+L GPT F+PVI H++R A + + G  YFVLLI+TDG + D  +TK+++V  S LP+SII+VGVG  +F  M  LD D   +    + A RD VQFV  R Y+    D S N   S   LAKDVLAE+P Q   YM  +
Sbjct:   77 FVRKFILDYFFEERENLRFDL--YDVDSKSPNLSKHDFLGQVFCTLGEIVGSQGSRLE--------KPIVGIPGKKCGTIILTAEELNCCRDAVLMQFCANKLDKKDFFGKSDPFLVFYRSNEDGSFTICHKTEVVKNTLNPVWQAFKISVRALCNGDYDRTIKVEVYDWDRD---------GSHDFIGEFTTSYRELSRGQS-QFNVYEVVNPKKKGKKKKYTNSGTVTLLSFLVETEVSFLDYIKGGTQINFTVAIDFTASNGNPAQPTSLHYMNPYQLNAYGMALKAVGEIVQDYDSDKMFPALGFGAKLPPDGRISHEFALNGNPQNPYCDGIEGVMEAYYRSLKSVQLYGPTNFAPVINHVARYASSVKDGSQYFVLLIVTDGVISDMAQTKESIVNASKLPMSIIIVGVGPAEFDAMVELDGDDVRVSSRGKYAERDIVQFVPFRDYI----DRSGNHILSMARLAKDVLAEIPEQFLSYMRAR 542          
BLAST of Copine-3 vs. Ensembl Human
Match: CPNE8 (copine 8 [Source:HGNC Symbol;Acc:HGNC:23498])

HSP 1 Score: 318.931 bits (816), Expect = 1.075e-99
Identity = 194/490 (39.59%), Postives = 289/490 (58.98%), Query Frame = 1
Query:  358 FDAKLCIEYLFEEKQMIIIEIFEYDITQDGDNL-----LGEVDCSIGRVIHSGGVVLKPLEITDEFKTTLGPLSPEVGIYV---EEDLTAKENIELKIRGIGLAKTEIFGKTDPYLMIFRCNNRSRYVQCYRTEVLKNTQNPDWSPIVVSYERLCNNDLNSVLCLRVYCGDGTLKESEEVDIACDQLVGEIKVTARELIQMRRMEEKQFELINPXXXXXXXSYLNSGIISVRAQKTNSEPTFLDFMFQGLELNFIVAIDLTLSNGDSSLPSSLHFMDCSLTNEYSVAIQAVLEILQEYDNDELFPAFGFGARVPPDYKICHEYPLNGDFENPYCRGAEGVIHAYQQTLKEVKLAGPTCFSPVIRHISRLAKASESGKHYFVLLILTDGSVDDWVETKKAVVETSYLPXXXXXXXXXXXKFSDMETLDQDFGLLMVSNEKACRDNVQFVKMRRYLRVAADGSDNIRWSKVALAKDVLAELPYQVNEYMHRK 1803
            F  K  ++Y FEE++ +  ++  YD+     NL     LG+V C++G ++ S G  L+        K  +G    + G  +   EE    ++ + ++     L K + FGK+DP+L+ +R N    +  C++TEV+KNT NP W    +S   LCN D +  + + VY  D                +GE   + REL + +  +   +E++NPKKK KKK Y NSG +++ +    +E +FLD++  G ++NF VAID T SNG+ + P+SLH+M+    N Y +A++AV EI+Q+YD+D++FPA GFGA++PPD +I HE+ LNG+ +NPYC G EGV+ AY ++LK V+L GPT F+PVI H++R A + + G  YFVLLI+TDG + D  +TK+++V  S LP+SII+VGVG  +F  M  LD D   +    + A RD VQFV  R Y+    D S N   S   LAKDVLAE+P Q   YM  +
Sbjct:   65 FVRKFILDYFFEERENLRFDL--YDVDSKSPNLSKHDFLGQVFCTLGEIVGSQGSRLE--------KPIVGIPGKKCGTIILTAEELNCCRDAVLMQFCANKLDKKDFFGKSDPFLVFYRSNEDGSFTICHKTEVVKNTLNPVWQAFKISVRALCNGDYDRTIKVEVYDWDRD---------GSHDFIGEFTTSYRELSRGQS-QFNVYEVVNPKKKGKKKKYTNSGTVTLLSFLVETEVSFLDYIKGGTQINFTVAIDFTASNGNPAQPTSLHYMNPYQLNAYGMALKAVGEIVQDYDSDKMFPALGFGAKLPPDGRISHEFALNGNPQNPYCDGIEGVMEAYYRSLKSVQLYGPTNFAPVINHVARYASSVKDGSQYFVLLIVTDGVISDMAQTKESIVNASKLPMSIIIVGVGPAEFDAMVELDGDDVRVSSRGKYAERDIVQFVPFRDYI----DRSGNHILSMARLAKDVLAEIPEQFLSYMRAR 530          
BLAST of Copine-3 vs. Ensembl Human
Match: CPNE5 (copine 5 [Source:HGNC Symbol;Acc:HGNC:2318])

HSP 1 Score: 313.153 bits (801), Expect = 6.331e-97
Identity = 191/497 (38.43%), Postives = 284/497 (57.14%), Query Frame = 1
Query:  358 FDAKLCIEYLFEEKQMIIIEIFEYDITQ---DGDNLLGEVDCSIGRVIHSGGVVL-KPLEITD-EFKTTLGPLSPEVG-------------IYVEEDLTAKENIELKIRGIGLAKTEIFGKTDPYLMIFRCNNRSRYVQCYRTEVLKNTQNPDWSPIVVSYERLCNNDLNSVLCLRVYCGDGTLKESEEVDIACDQLVGEIKVTARELIQMRRMEEKQFELINPXXXXXXXSYLNSGIISVRAQKTNSEPTFLDFMFQGLELNFIVAIDLTLSNGDSSLPSSLHFMDCSLTNEYSVAIQAVLEILQEYDNDELFPAFGFGARVPPDYKICHEYPLNGDFENPYCRGAEGVIHAYQQTLKEVKLAGPTCFSPVIRHISRLAKASESGKHYFVLLILTDGSVDDWVETKKAVVETSYLPXXXXXXXXXXXKFSDMETLDQDFGLLMVSNEKACRDNVQFVKMRRYLRVAADGSDNIRWSKVALAKDVLAELPYQVNEYM 1794
            F  K  ++Y FEEKQ +  ++++ D         + LG+  C++G ++ S G  L KPL I      +  G   P V              +  EE    ++   ++     L K + FGK+DP+L+ +R N    +  C++TEV+KNT NP W    +    LCN D +  + + VY  D                +GE   + REL + +  +   +E++NPKKK KKK Y+NSG +++ +    SE TFLD++  G ++NF VAID T SNG+ S  +SLH+M     N Y++A+ AV EI+Q YD+D++FPA GFGA++PPD ++ HE+PLNG+ ENP C G +G++ AY ++L+ V+L GPT F+PV+ H++R A A + G  Y VLLI+TDG + D  +TK+A+V  + LP+SII+VGVG  +F  M  LD D   +    + A RD VQFV  R Y+    D + N   S   LA+DVLAE+P Q+  YM
Sbjct:   76 FVRKFIVDYFFEEKQNLRFDLYDVDSKSPDLSKHDFLGQAFCTLGEIVGSPGSRLEKPLTIGAFSLNSRTGKPMPAVSNGGVPGKKCGTIILSAEELSNCRDVATMQFCANKLDKKDFFGKSDPFLVFYRSNEDGTFTICHKTEVMKNTLNPVWQTFSIPVRALCNGDYDRTIKVEVYDWDRD---------GSHDFIGEFTTSYRELARGQS-QFNIYEVVNPKKKMKKKKYVNSGTVTLLSFAVESECTFLDYIKGGTQINFTVAIDFTASNGNPSQSTSLHYMSPYQLNAYALALTAVGEIIQHYDSDKMFPALGFGAKLPPDGRVSHEFPLNGNQENPSCCGIDGILEAYHRSLRTVQLYGPTNFAPVVTHVARNAAAVQDGSQYSVLLIITDGVISDMAQTKEAIVNAAKLPMSIIIVGVGQAEFDAMVELDGDDVRISSRGKLAERDIVQFVPFRDYV----DRTGNHVLSMARLARDVLAEIPDQLVSYM 558          
BLAST of Copine-3 vs. Ensembl Human
Match: CPNE9 (copine family member 9 [Source:HGNC Symbol;Acc:HGNC:24336])

HSP 1 Score: 310.842 bits (795), Expect = 1.483e-96
Identity = 190/489 (38.85%), Postives = 285/489 (58.28%), Query Frame = 1
Query:  358 FDAKLCIEYLFEEKQMIIIEIFEYD----ITQDGDNLLGEVDCSIGRVIHSGGVVLKPLEITDEFKTTLGPLSPEVG---IYVEEDLTAKENIELKIRGIGLAKTEIFGKTDPYLMIFRCNNRSRYVQCYRTEVLKNTQNPDWSPIVVSYERLCNNDLNSVLCLRVYCGDGTLKESEEVDIACDQLVGEIKVTARELIQMRRMEEKQFELINPXXXXXXXSYLNSGIISVRAQKTNSEPTFLDFMFQGLELNFIVAIDLTLSNGDSSLPSSLHFMDCSLTNEYSVAIQAVLEILQEYDNDELFPAFGFGARVPPDYKICHEYPLNGDFENPYCRGAEGVIHAYQQTLKEVKLAGPTCFSPVIRHISRLAKASESGKHYFVLLILTDGSVDDWVETKKAVVETSYLPXXXXXXXXXXXKFSDMETLDQDFGLLMVSNEKACRDNVQFVKMRRYLRVAADGSDNIRWSKVALAKDVLAELPYQVNEYMHRK 1803
            F  K  ++Y FEEKQ +  +++  D    I++  D  LG+   ++G VI   G  ++        +T  G    + G   +  EE    ++   +++    L K + FGK+DP+L+ +R N    +  C++TEV+KNT NP W P  +    LCN D +  + + VY  D                +GE   + REL + +  +   +E++NP+KK KKK Y+NSG +++ +   +SE TF+D++  G +LNF VAID T SNG+   P+SLH+M     + Y++A++AV EI+Q+YD+D+LFPA+GFGA++PP+ +I H++PLN + E+P C G EGV+ +Y Q+L+ V+L GPT F+PVI  ++R A     G  Y+VLLI+TDG + D  +TK+A+V  S LP+SII+VGVG   F  ME LD D   +      A RD VQFV  R Y+    D S N   S   LAKDVLAE+P Q+  YM  +
Sbjct:   67 FVRKFVLDYFFEEKQNLRFDVYNVDSKTNISKPKD-FLGQAFLALGEVIGGQGSRVE--------RTLTGVPGKKCGTILLTAEELSNCRDIATMQLCANKLDKKDFFGKSDPFLVFYRSNEDGTFTICHKTEVVKNTLNPVWQPFSIPVRALCNGDYDRTVKIDVYDWDRD---------GSHDFIGEFTTSYRELSKAQN-QFTVYEVLNPRKKCKKKKYVNSGTVTLLSFSVDSEFTFVDYIKGGTQLNFTVAIDFTASNGNPLQPTSLHYMSPYQLSAYAMALKAVGEIIQDYDSDKLFPAYGFGAKLPPEGRISHQFPLNNNDEDPNCAGIEGVLESYFQSLRTVQLYGPTYFAPVINQVARAAAKISDGSQYYVLLIITDGVISDMTQTKEAIVSASSLPMSIIIVGVGPAMFEAMEELDGDDVRVSSRGRYAERDIVQFVPFRDYV----DRSGNQVLSMARLAKDVLAEIPEQLLSYMRTR 532          
BLAST of Copine-3 vs. Ensembl Human
Match: CPNE2 (copine 2 [Source:HGNC Symbol;Acc:HGNC:2315])

HSP 1 Score: 307.76 bits (787), Expect = 1.793e-95
Identity = 190/499 (38.08%), Postives = 284/499 (56.91%), Query Frame = 1
Query:  355 TFDAKLCIEYLFEEKQMIIIEIFEYDITQ---DGDNLLGEVDCSIGRVIHSGGVVLKPLEITDEFKTTLGPLSPEVGIYVEEDLTAKENIELKIRGIGLAKTEIFGKTDPYLMIFRCNNRSRYVQCYRTEVLKNTQNPDWSPIVVSYERLCNNDLN---SVLCLRVYCGDGTLKESEEVDIACDQLVGEIKVTARELIQMRRMEEKQFELINPXXXXXXXSYLNSGIISVRAQKTNSEPTFLDFMFQGLELNFIVAIDLTLSNGDSSLPSSLHFMDCSLTNEYSVAIQAVLEILQEYDNDELFPAFGFGARVPPDYKICHEYPLNGDFENPYCRGAEGVIHAYQQTLKEVKLAGPTCFSPVIRHISRLAKAS---ESGKHYFVLLILTDGSVDDWVETKKAVVETSYLPXXXXXXXXXXXKFSDMETLDQDFGLLMV-SNEKACRDNVQFVKMRRYLRVAADGSDNIRWSKVALAKDVLAELPYQVNEYM-HRKTKLTN 1818
             F  K  ++Y FEE Q +   +F+ D +    D  + LG+  CS+G ++ S  +    L + D+      P    +     ++L+    I L + G  L K ++FGK+DP+L  ++  +  +++  +RTEV+K T +P W P  V    LC+ D+     V+C   Y  DG               +GE + +  ++ + R     +FE INPKK++KKK+Y NSGII +R+ K N + +FLD++  G +L F V ID T SNG+   PSSLH+++   TNEY  AI AV +I+Q+YD+D++FPA GFGA++PPD+K+ HE+ +N +  NP+C G +G+  AY   L  ++  GPT FSP++ H++R A  +    +   YF+LLI+TDG + D  ET+ AVV+ S LP+SII+VGVG   F+ ME LD D  +L   + E+A RD VQFV  R +   A          K  LAK VLAELP QV +Y  H+    TN
Sbjct:   74 AFSKKFVLDYHFEEVQKLKFALFDQDKSSMRLDEHDFLGQFSCSLGTIVSSKKITRPLLLLNDK------PAGKGLITIAAQELSDNRVITLSLAGRRLDKKDLFGKSDPFLEFYKPGDDGKWMLVHRTEVIKYTLDPVWKPFTVPLVSLCDGDMEKPIQVMCYD-YDNDGG-----------HDFIGEFQTSVSQMCEARDSVPLEFECINPKKQRKKKNYKNSGIIILRSCKINRDYSFLDYILGGCQLMFTVGIDFTASNGNPLDPSSLHYINPMGTNEYLSAIWAVGQIIQDYDSDKMFPALGFGAQLPPDWKVSHEFAINFNPTNPFCSGVDGIAQAYSACLPHIRFYGPTNFSPIVNHVARFAAQATQQRTATQYFILLIITDGVISDMEETRHAVVQASKLPMSIIIVGVGNADFAAMEFLDGDSRMLRSHTGEEAARDIVQFVPFREFRNAA----------KETLAKAVLAELPQQVVQYFKHKNLPPTN 544          
BLAST of Copine-3 vs. Ensembl Celegans
Match: gem-4 (Gon-2 Extragenic Modifier [Source:UniProtKB/TrEMBL;Acc:Q22422])

HSP 1 Score: 243.432 bits (620), Expect = 6.796e-71
Identity = 174/513 (33.92%), Postives = 267/513 (52.05%), Query Frame = 1
Query:  358 FDAKLCIEYLFEEKQMIIIEIFEYDITQ-----DGDNLLGEVDCSIGRVI-------HSGGVVLKPLEITDEFKTTLGPLSPEVGIYVEEDLTAKENIELKIRGIGLAKTEIFGKTDPYLMIFRCNNRSRYVQCYRTEVLKNTQNPDWSPIVVSYERLCNNDLNSVLCLRVYCGDGTLKESEEVDIACDQLVGEIKVTARELI-QMRRMEEKQFELINPXXXXXXXSYL-NSGIISVRAQKTNSEPTFLDFMFQGLELNFIVAIDLTLSNGDSSLPSSLHFMDCSLTNEYSVAIQAVLEILQEYDNDELFPAFGFGARVPPDYKICHEYPLNGDFENPYCRGAEGVIHAYQQTLKEVKLAGPTCFSPVIRHISRLA-KASESGKHYFVLLILTDGSVDDWVETKKAVVETSYLPXXXXXXXXXXXKFSDMETLDQDFGLLMVSNEKACRDNVQFVKMRRYLRVAADGSDNIRWSKVALAKDVLAELPYQVNEYMHRKTKLTNYLENLPTQRST 1851
            F     I Y FEE Q+   E+++ D  +      G + LG  +C + +++       H GG      +  ++ K +    +  + I  EED    E I+  + G  L + + FGK+DPYL   R  +       ++TEV   T NP WS +++S + LC  +++  + +  Y  +   K+        D ++G  + T   LI Q    E  Q  LIN KKK KK +   NSG++ +   K   EPTFLDF+  G +L+F VA+D T SNG+   P SLH+M   + N+Y +A+++VL I Q Y++ + F A+GFGA++P    +   +PL+ + ++    G  GV++AY+  L+ V L GPT FSP+I  ++  A K  ++   Y +LLI+TDG + D   T   V+  S LP+SII++GVG   F  M  LD D  LL   +  A RD VQFV MR +L   + G  N       LA++VL E+P Q+  YM R+   T    + P QR +
Sbjct:   84 FKTTFLIPYFFEETQLFRFELYDVDSPKVGADMSGHDFLGRFECVLAQIVSYSTLRAHLGGKHSIGAQWKNKDKVSK---NGSITIRAEED-EKNEKIQFDVCGEKLDRKDFFGKSDPYLNFKRRFDDGSSHMIHQTEVKPKTLNPRWSTVLISTQALCGKNMDRPIIIECYDHEKFKKQ--------DDIIGTAQTTLNTLIEQAGGGESTQIPLINEKKKLKKGAKYKNSGMLKIWNAKLVLEPTFLDFIAGGTQLDFAVAVDFTASNGNPRTPGSLHYMATGIPNQYEIALRSVLTICQHYNSSKTFEAYGFGAKLPNHQTVSAVFPLDLNRQSSSVVGINGVMNAYRHALQNVTLYGPTNFSPIIVEVANKAQKMMKTTARYQILLIITDGIISDMYATINTVINASGLPLSIIIIGVGNEDFERMHELDSDDALLQQDSRIAERDIVQFVTMRDFLGNQSGGYLNTDTIMENLAREVLYEVPDQLTGYMKRR-GFTPKSRDDPWQRDS 583          
BLAST of Copine-3 vs. Ensembl Celegans
Match: gem-4 (Gon-2 Extragenic Modifier [Source:UniProtKB/TrEMBL;Acc:Q22422])

HSP 1 Score: 243.432 bits (620), Expect = 6.796e-71
Identity = 174/513 (33.92%), Postives = 267/513 (52.05%), Query Frame = 1
Query:  358 FDAKLCIEYLFEEKQMIIIEIFEYDITQ-----DGDNLLGEVDCSIGRVI-------HSGGVVLKPLEITDEFKTTLGPLSPEVGIYVEEDLTAKENIELKIRGIGLAKTEIFGKTDPYLMIFRCNNRSRYVQCYRTEVLKNTQNPDWSPIVVSYERLCNNDLNSVLCLRVYCGDGTLKESEEVDIACDQLVGEIKVTARELI-QMRRMEEKQFELINPXXXXXXXSYL-NSGIISVRAQKTNSEPTFLDFMFQGLELNFIVAIDLTLSNGDSSLPSSLHFMDCSLTNEYSVAIQAVLEILQEYDNDELFPAFGFGARVPPDYKICHEYPLNGDFENPYCRGAEGVIHAYQQTLKEVKLAGPTCFSPVIRHISRLA-KASESGKHYFVLLILTDGSVDDWVETKKAVVETSYLPXXXXXXXXXXXKFSDMETLDQDFGLLMVSNEKACRDNVQFVKMRRYLRVAADGSDNIRWSKVALAKDVLAELPYQVNEYMHRKTKLTNYLENLPTQRST 1851
            F     I Y FEE Q+   E+++ D  +      G + LG  +C + +++       H GG      +  ++ K +    +  + I  EED    E I+  + G  L + + FGK+DPYL   R  +       ++TEV   T NP WS +++S + LC  +++  + +  Y  +   K+        D ++G  + T   LI Q    E  Q  LIN KKK KK +   NSG++ +   K   EPTFLDF+  G +L+F VA+D T SNG+   P SLH+M   + N+Y +A+++VL I Q Y++ + F A+GFGA++P    +   +PL+ + ++    G  GV++AY+  L+ V L GPT FSP+I  ++  A K  ++   Y +LLI+TDG + D   T   V+  S LP+SII++GVG   F  M  LD D  LL   +  A RD VQFV MR +L   + G  N       LA++VL E+P Q+  YM R+   T    + P QR +
Sbjct:   84 FKTTFLIPYFFEETQLFRFELYDVDSPKVGADMSGHDFLGRFECVLAQIVSYSTLRAHLGGKHSIGAQWKNKDKVSK---NGSITIRAEED-EKNEKIQFDVCGEKLDRKDFFGKSDPYLNFKRRFDDGSSHMIHQTEVKPKTLNPRWSTVLISTQALCGKNMDRPIIIECYDHEKFKKQ--------DDIIGTAQTTLNTLIEQAGGGESTQIPLINEKKKLKKGAKYKNSGMLKIWNAKLVLEPTFLDFIAGGTQLDFAVAVDFTASNGNPRTPGSLHYMATGIPNQYEIALRSVLTICQHYNSSKTFEAYGFGAKLPNHQTVSAVFPLDLNRQSSSVVGINGVMNAYRHALQNVTLYGPTNFSPIIVEVANKAQKMMKTTARYQILLIITDGIISDMYATINTVINASGLPLSIIIIGVGNEDFERMHELDSDDALLQQDSRIAERDIVQFVTMRDFLGNQSGGYLNTDTIMENLAREVLYEVPDQLTGYMKRR-GFTPKSRDDPWQRDS 583          
BLAST of Copine-3 vs. Ensembl Celegans
Match: nra-1 (Nicotinic receptor-associated protein 1 [Source:UniProtKB/Swiss-Prot;Acc:Q9XUB9])

HSP 1 Score: 229.95 bits (585), Expect = 6.616e-66
Identity = 168/499 (33.67%), Postives = 256/499 (51.30%), Query Frame = 1
Query:  358 FDAKLCIEYLFEEKQMIIIEIFEYDITQDGDNL-----LGEVDCSIGRVI-------HSGGVVLKPLEITDEFKTTLGPLSPEVGIYVEEDLTAKENIELKIRGIGLAKTEIFGKTDPYLMIFRCNNRSRYVQCYRTEVLKNTQNPDWSPIVVSYERLCNNDLNSVLCLRVYCGDGTLKESE---EVDIACDQLVGEIKVTARELIQMRRMEEKQFELINPXXXXXXXSYLN-SGIISVRAQKTNSEPTFLDFMFQGLELNFIVAIDLTLSNGDSSLPSSLHFMDCSLTNEYSVAIQAVLEILQEYDNDELFPAFGFGARVPPDYKICHEYPLNGDFENPYCRGAEGVIHAYQQTLKEVKLAGPTCFSPVIRHISRLAKAS-ESGKHYFVLLILTDGSVDDWVETKKAVVETSYLPXXXXXXXXXXXKFSDMETLDQDFGLLMVSNEKACRDNVQFVKMRRYLRVAADGSDNIRWSKVALAKDVLAELPYQVNEYMHRK 1803
            F     + Y FEE Q++  EI++ D    G +L     LG  +C + +++       H G       +  ++ K T    +  + IY EED  A E I+  + G GL K + FGK+DPYL   R  +       +RTEV   T +P W+ + ++ + LC  D +  + +  Y  D   K  E   +   + D L+G  + T  EL++    +  +  L N KKK KK      SG + +   +   EPTFLDF+  G +L+F VA+D T SNG     SSLHFM     N+Y +A+++VL I Q Y++ + F AFGFGA++P    +   +PL+         G  GV+ AY+  L  V+L GPT F+P+I +++R A+        Y +LLI+TDG + D   T ++++  S LP+SII++GVG   F  M  LD D  LL   +  A RD VQFV MR +L        +    +  LA++VL E+P Q+  YM ++
Sbjct:   83 FTKTFLLPYFFEETQLLRFEIYDADSPTVGQDLSSHDFLGRFECVLAQIVSYSTLKAHLGKTGQIGAQWRNKDKNTK---TGSITIYAEEDEKA-EKIQFDVCGEGLDKKDFFGKSDPYLNFKRKFDDGSTHLIHRTEVKPKTLDPRWATVQINTQTLCAKDGDRPIIIECYDHDKWKKGEEPRGDAKFSRDDLIGTAQTTLNELLRGSS-DAVEILLTNEKKKAKKGDKYKCSGTLKIWNSRIVIEPTFLDFISGGTQLDFAVAVDFTASNGPPKSSSSLHFMSADRPNQYELALRSVLSICQHYNSSKTFEAFGFGAKLPNQSSVSAIFPLDLQRGTSEVVGITGVMTAYRHALSNVQLYGPTNFAPIIENVARKAQNMIHDSARYQILLIITDGIISDMHATIRSIISASGLPLSIIIIGVGNEDFEKMHELDSDDALLQQDSRIAQRDIVQFVTMREFLNNGQGLYLDPDVIQENLAREVLYEVPAQLTGYMKQR 576          
BLAST of Copine-3 vs. Ensembl Celegans
Match: nra-1 (Nicotinic receptor-associated protein 1 [Source:UniProtKB/Swiss-Prot;Acc:Q9XUB9])

HSP 1 Score: 227.639 bits (579), Expect = 4.534e-65
Identity = 167/496 (33.67%), Postives = 253/496 (51.01%), Query Frame = 1
Query:  358 FDAKLCIEYLFEEKQMIIIEIFEYDITQDGDNL-----LGEVDCSIGRVI-------HSGGVVLKPLEITDEFKTTLGPLSPEVGIYVEEDLTAKENIELKIRGIGLAKTEIFGKTDPYLMIFRCNNRSRYVQCYRTEVLKNTQNPDWSPIVVSYERLCNNDLNSVLCLRVYCGDGTLKESEEVDIACDQLVGEIKVTARELIQMRRMEEKQFELINPXXXXXXXSYLN-SGIISVRAQKTNSEPTFLDFMFQGLELNFIVAIDLTLSNGDSSLPSSLHFMDCSLTNEYSVAIQAVLEILQEYDNDELFPAFGFGARVPPDYKICHEYPLNGDFENPYCRGAEGVIHAYQQTLKEVKLAGPTCFSPVIRHISRLAKAS-ESGKHYFVLLILTDGSVDDWVETKKAVVETSYLPXXXXXXXXXXXKFSDMETLDQDFGLLMVSNEKACRDNVQFVKMRRYLRVAADGSDNIRWSKVALAKDVLAELPYQVNEYMHRK 1803
            F     + Y FEE Q++  EI++ D    G +L     LG  +C + +++       H G       +  ++ K T    +  + IY EED  A E I+  + G GL K + FGK+DPYL   R  +       +RTEV   T +P W+ + ++ + LC  D +  + +  Y  D   K         D L+G  + T  EL++    +  +  L N KKK KK      SG + +   +   EPTFLDF+  G +L+F VA+D T SNG     SSLHFM     N+Y +A+++VL I Q Y++ + F AFGFGA++P    +   +PL+         G  GV+ AY+  L  V+L GPT F+P+I +++R A+        Y +LLI+TDG + D   T ++++  S LP+SII++GVG   F  M  LD D  LL   +  A RD VQFV MR +L        +    +  LA++VL E+P Q+  YM ++
Sbjct:   83 FTKTFLLPYFFEETQLLRFEIYDADSPTVGQDLSSHDFLGRFECVLAQIVSYSTLKAHLGKTGQIGAQWRNKDKNTK---TGSITIYAEEDEKA-EKIQFDVCGEGLDKKDFFGKSDPYLNFKRKFDDGSTHLIHRTEVKPKTLDPRWATVQINTQTLCAKDGDRPIIIECYDHDKWKK---------DDLIGTAQTTLNELLRGSS-DAVEILLTNEKKKAKKGDKYKCSGTLKIWNSRIVIEPTFLDFISGGTQLDFAVAVDFTASNGPPKSSSSLHFMSADRPNQYELALRSVLSICQHYNSSKTFEAFGFGAKLPNQSSVSAIFPLDLQRGTSEVVGITGVMTAYRHALSNVQLYGPTNFAPIIENVARKAQNMIHDSARYQILLIITDGIISDMHATIRSIISASGLPLSIIIIGVGNEDFEKMHELDSDDALLQQDSRIAQRDIVQFVTMREFLNNGQGLYLDPDVIQENLAREVLYEVPAQLTGYMKQR 564          
BLAST of Copine-3 vs. Ensembl Celegans
Match: cpna-5 (Copine family protein 5 [Source:UniProtKB/Swiss-Prot;Acc:Q09219])

HSP 1 Score: 142.124 bits (357), Expect = 6.740e-35
Identity = 148/537 (27.56%), Postives = 248/537 (46.18%), Query Frame = 1
Query:  349 DITFDAKLCIEYLFEEKQMIIIEIFEYDITQDG----------------DNLLGEVDCSIGRVIHSGGVVLKPL----EITDEFKTTLGPLSPEVGIYVEEDLTAKEN-IELKIRGIGLAKTE-IFGKTDPYLMIFRC---NNRSRYVQCYRTEVLKNTQNPDWSPIVVSYERLCNNDLNSVLCLRVYCGDGTLKESEEVDIACDQLVGEIKVTARELIQMRRMEEKQFELINPXXXXXXXSYLNSGIISVRAQKTNSEPTFLDFMFQGLELNFIVAIDLTLSNGDSSLPSSLHFMDCS-LTNEYSVAIQAVLEILQEYDNDELFPAFGFGARVPPDYKICHEYPLNGDFENPYCRGAEGVIHAYQQTLKEVKLAGPTCFSPVIRHISRLAKASE-SGKHYFVLLILTDGSVDDWVETKKAVVETSYLPXXXXXXXXXXXKFSDMETLDQDFGLLMVSNEKACRDNVQFVKMRRYLRVAADGSDNIRWSKVALAKDVLAELPYQVNEYMHRKTKLTNYLENLPTQ--RSTAVFSSCL 1872
            +I F  K   +Y+FE+ Q+I   +F     +D                 D L+G     + R +   G +   L     +TDE+   LG      GI V  ++  KE  I ++  G  L + + ++ +T  +  +FR     +    V  Y +E LKN  +P W+   +  +   +N  N +L + V   D   KE           +G+  +T    ++     +  + +IN  KK +KKSY NSG + +      S  +FLD++  G +L+F + +D        S P  +H +D      E  +AI+A+  I+++Y  + LF AFG GA++PP +   +E+ LN    +P CRG +GV+ AY++T   V     +  SPVI +++R++  S   G HY VL + T G V D  E ++A+   S  P+SI+++G+G   FS ++        L    +   RD VQF+ ++  L    +G++    +K  +A+  L  +P  + +YMH      N     P Q  RS    SS L
Sbjct:  111 NIVFTDKFSYQYVFEKTQLIK-AVFSRCHDRDKPSSSSRDILATSIFKVDELIGSFGLQLRRQLEKNGNIASALSGTQRVTDEY---LG------GIIVSAEMPEKEQPIVVQFHGKSLDRKDFLWDETAVFFRVFRLEEGKDDDSLVFLYESEALKNHSHPQWAEFRLDTQDAADNR-NRLLEIWVMYKDVDGKEG---------YIGKF-LTTYAKMKYGPGSDNVYSVINDVKKAQKKSYENSGKMELVKFTDVSFYSFLDYIVSGTQLHFEIGVDF-------SSPEPVHELDQRRFDGELHMAIRAIGSIIRDYTPNRLFAAFGIGAKIPPTFHESNEFFLNFSM-DPICRGLDGVMEAYRKTQTMVTPLKESKLSPVINYVTRMSHRSGFRGLHYHVLALFTRGEVTDLKEIQQALNSASDAPLSILIIGMGDFDFSSLQK-------LCSKRKDGRRDVVQFIHLKSLL----NGAEAPWLNKSRIAETALRHVPQHMVQYMHN----ANIAAKPPIQVCRSPLFHSSSL 603          
BLAST of Copine-3 vs. Ensembl Zebrafish
Match: cpne5b (copine Vb [Source:ZFIN;Acc:ZDB-GENE-040426-1398])

HSP 1 Score: 331.257 bits (848), Expect = 2.254e-104
Identity = 192/486 (39.51%), Postives = 288/486 (59.26%), Query Frame = 1
Query:  358 FDAKLCIEYLFEEKQMIIIEIFEYDITQ---DGDNLLGEVDCSIGRVIHSGGVVL-KPLEITDEFKTTLGPLSPEVGIYVEEDLTAKENIELKIRGIGLAKTEIFGKTDPYLMIFRCNNRSRYVQCYRTEVLKNTQNPDWSPIVVSYERLCNNDLNSVLCLRVYCGDGTLKESEEVDIACDQLVGEIKVTARELIQMRRMEEKQFELINPXXXXXXXSYLNSGIISVRAQKTNSEPTFLDFMFQGLELNFIVAIDLTLSNGDSSLPSSLHFMDCSLTNEYSVAIQAVLEILQEYDNDELFPAFGFGARVPPDYKICHEYPLNGDFENPYCRGAEGVIHAYQQTLKEVKLAGPTCFSPVIRHISRLAKASESGKHYFVLLILTDGSVDDWVETKKAVVETSYLPXXXXXXXXXXXKFSDMETLDQDFGLLMVSNEKACRDNVQFVKMRRYLRVAADGSDNIRWSKVALAKDVLAELPYQVNEYMHRK 1803
            F  K  ++Y FEEKQ +  ++++ D         + LG++ C++G ++ S    L KPL          G     + +  EE    +++  ++     L K + FGK+DP+++ +R N    +  C++TEV+KNT NP W P  +    LCN D +  + + VY  D                +GE   + REL + +  +   +E++NPKKK KKK Y+NSG +++ +    SE TFLD++  G ++NF VAID T SNG+ S  +SLH+M+    N Y++A++AV EI+Q+YD+D++FPA GFGA++PPD ++ HE+PLNG+ ENPYC G EG++ AY Q+LK V+L GPT F+PV+ H++R A A + G  YF+LLI+TDG + D  +TK+A+V  + LP+SII+VGVG  +F  M  LD D   +    + A RD VQFV  R Y+    D + N   S   LAKDVLAE+P Q   YM  +
Sbjct:   76 FVRKYILDYFFEEKQNLRFDLYDVDSKSPDLSKHDFLGQMFCTLGEIVGSPASRLEKPL------GGISGKNCGTIVLSAEELGNCRDSATMQFCANKLDKKDFFGKSDPFMVFYRSNEDGTFTICHKTEVVKNTLNPVWQPFTIPVRALCNGDYDRTIKVEVYDWDRD---------GSHDFIGEFTTSYRELARGQS-QFNVYEVVNPKKKMKKKKYVNSGTVTLLSFSVESESTFLDYIKGGTQINFTVAIDFTASNGNPSQSTSLHYMNPYQMNAYALALKAVGEIIQDYDSDKMFPALGFGAKLPPDGRVSHEFPLNGNIENPYCNGIEGILEAYHQSLKTVQLYGPTNFAPVVNHVARYAAAVQDGSQYFILLIITDGVISDMSQTKEAIVNAAKLPMSIIIVGVGQAEFDAMVELDGDDIRISSRGKLAERDIVQFVPFRDYM----DRTGNHVLSMARLAKDVLAEIPDQFISYMKSR 541          
BLAST of Copine-3 vs. Ensembl Zebrafish
Match: cpne5b (copine Vb [Source:ZFIN;Acc:ZDB-GENE-040426-1398])

HSP 1 Score: 328.561 bits (841), Expect = 2.812e-103
Identity = 193/493 (39.15%), Postives = 291/493 (59.03%), Query Frame = 1
Query:  358 FDAKLCIEYLFEEKQMIIIEIFEYDITQDGD----------NLLGEVDCSIGRVIHSGGVVL-KPLEITDEFKTTLGPLSPEVGIYVEEDLTAKENIELKIRGIGLAKTEIFGKTDPYLMIFRCNNRSRYVQCYRTEVLKNTQNPDWSPIVVSYERLCNNDLNSVLCLRVYCGDGTLKESEEVDIACDQLVGEIKVTARELIQMRRMEEKQFELINPXXXXXXXSYLNSGIISVRAQKTNSEPTFLDFMFQGLELNFIVAIDLTLSNGDSSLPSSLHFMDCSLTNEYSVAIQAVLEILQEYDNDELFPAFGFGARVPPDYKICHEYPLNGDFENPYCRGAEGVIHAYQQTLKEVKLAGPTCFSPVIRHISRLAKASESGKHYFVLLILTDGSVDDWVETKKAVVETSYLPXXXXXXXXXXXKFSDMETLDQDFGLLMVSNEKACRDNVQFVKMRRYLRVAADGSDNIRWSKVALAKDVLAELPYQVNEYMHRK 1803
            F  K  ++Y FEEKQ +  ++++ D ++  D          + LG++ C++G ++ S    L KPL          G     + +  EE    +++  ++     L K + FGK+DP+++ +R N    +  C++TEV+KNT NP W P  +    LCN D +  + + VY  D                +GE   + REL + +  +   +E++NPKKK KKK Y+NSG +++ +    SE TFLD++  G ++NF VAID T SNG+ S  +SLH+M+    N Y++A++AV EI+Q+YD+D++FPA GFGA++PPD ++ HE+PLNG+ ENPYC G EG++ AY Q+LK V+L GPT F+PV+ H++R A A + G  YF+LLI+TDG + D  +TK+A+V  + LP+SII+VGVG  +F  M  LD D   +    + A RD VQFV  R Y+    D + N   S   LAKDVLAE+P Q   YM  +
Sbjct:   81 FVRKYILDYFFEEKQNLRFDLYDVD-SKSPDLSKHKPLELYDFLGQMFCTLGEIVGSPASRLEKPL------GGISGKNCGTIVLSAEELGNCRDSATMQFCANKLDKKDFFGKSDPFMVFYRSNEDGTFTICHKTEVVKNTLNPVWQPFTIPVRALCNGDYDRTIKVEVYDWDRD---------GSHDFIGEFTTSYRELARGQS-QFNVYEVVNPKKKMKKKKYVNSGTVTLLSFSVESESTFLDYIKGGTQINFTVAIDFTASNGNPSQSTSLHYMNPYQMNAYALALKAVGEIIQDYDSDKMFPALGFGAKLPPDGRVSHEFPLNGNIENPYCNGIEGILEAYHQSLKTVQLYGPTNFAPVVNHVARYAAAVQDGSQYFILLIITDGVISDMSQTKEAIVNAAKLPMSIIIVGVGQAEFDAMVELDGDDIRISSRGKLAERDIVQFVPFRDYM----DRTGNHVLSMARLAKDVLAEIPDQFISYMKSR 552          
BLAST of Copine-3 vs. Ensembl Zebrafish
Match: cpne5a (copine Va [Source:ZFIN;Acc:ZDB-GENE-081105-9])

HSP 1 Score: 326.635 bits (836), Expect = 1.240e-102
Identity = 192/487 (39.43%), Postives = 292/487 (59.96%), Query Frame = 1
Query:  358 FDAKLCIEYLFEEKQMIIIEIFEYDITQDGD----NLLGEVDCSIGRVIHSGGVVL-KPLEITDEFKTTLGPLSPEVGIYVEEDLTAKENIELKIRGIGLAKTEIFGKTDPYLMIFRCNNRSRYVQCYRTEVLKNTQNPDWSPIVVSYERLCNNDLNSVLCLRVYCGDGTLKESEEVDIACDQLVGEIKVTARELIQMRRMEEKQFELINPXXXXXXXSYLNSGIISVRAQKTNSEPTFLDFMFQGLELNFIVAIDLTLSNGDSSLPSSLHFMDCSLTNEYSVAIQAVLEILQEYDNDELFPAFGFGARVPPDYKICHEYPLNGDFENPYCRGAEGVIHAYQQTLKEVKLAGPTCFSPVIRHISRLAKASESGKHYFVLLILTDGSVDDWVETKKAVVETSYLPXXXXXXXXXXXKFSDMETLDQDFGLLMVSNEKACRDNVQFVKMRRYLRVAADGSDNIRWSKVALAKDVLAELPYQVNEYMHRK 1803
            F  K  ++Y FEEKQ +  +I++ D ++  D    + LG+  C++G ++ S G  L KPL          G     + +  EE    ++   ++     L K + FG++DP+++ +R N    +  C++TEV+KNT NP W P  +    LCN D +  + + VY  D                +GE   + REL + +  +   +E++NPKKK KK+ Y+NSG +++ +    +E TFLD++  GL+++F VAID T SNG+ S  +SLH+M+    N Y++A++AV EI+Q+YD+D++FPA GFGA++PPD ++ HE+PLNG+ +NPYC G EG++ AY ++LK V+L GPT F+PVI H++R A A + G  YFVLLI+TDG + D  +TK+A+V  + LP+SII+VGVG  +F  M  LD D   +    + A RD VQFV  R Y+    D + N   S   LAKDVLAE+P Q+  YM  +
Sbjct:   76 FVRKYILDYFFEEKQNLRFDIYDID-SKSPDLAKHDFLGQTFCTLGEIVGSPGSRLEKPL------GGIPGKNCGTIILTAEELGNCRDCATMQFCANKLDKKDFFGRSDPFMVFYRSNEDGTFTICHKTEVVKNTLNPIWQPFTIPVRALCNGDYDRSIKVEVYDWDRD---------GSHDFIGEFTTSYRELSRGQS-QFNVYEVVNPKKKLKKRRYINSGTVTLLSFLVEAEHTFLDYIKAGLQIHFTVAIDFTASNGNPSQSTSLHYMNPYQMNAYAMALKAVGEIIQDYDSDKMFPALGFGAKLPPDGRVSHEFPLNGNVDNPYCNGMEGILEAYHESLKTVQLYGPTNFAPVINHVARYAAAVQDGSQYFVLLIITDGVISDMAQTKEAIVNAAKLPMSIIIVGVGQAEFDAMVELDGDDVRISSRGKLAERDIVQFVPFRDYM----DRTGNHVLSMARLAKDVLAEIPDQLILYMKSR 541          
BLAST of Copine-3 vs. Ensembl Zebrafish
Match: cpne8 (copine VIII [Source:ZFIN;Acc:ZDB-GENE-100809-1])

HSP 1 Score: 323.553 bits (828), Expect = 2.246e-101
Identity = 196/490 (40.00%), Postives = 292/490 (59.59%), Query Frame = 1
Query:  358 FDAKLCIEYLFEEKQMIIIEIFEYDITQDGDNL-----LGEVDCSIGRVIHSGGVVLKPLEITDEFKTTLGPLSPEVG---IYVEEDLTAKENIELKIRGIGLAKTEIFGKTDPYLMIFRCNNRSRYVQCYRTEVLKNTQNPDWSPIVVSYERLCNNDLNSVLCLRVYCGDGTLKESEEVDIACDQLVGEIKVTARELIQMRRMEEKQFELINPXXXXXXXSYLNSGIISVRAQKTNSEPTFLDFMFQGLELNFIVAIDLTLSNGDSSLPSSLHFMDCSLTNEYSVAIQAVLEILQEYDNDELFPAFGFGARVPPDYKICHEYPLNGDFENPYCRGAEGVIHAYQQTLKEVKLAGPTCFSPVIRHISRLAKASESGKHYFVLLILTDGSVDDWVETKKAVVETSYLPXXXXXXXXXXXKFSDMETLDQDFGLLMVSNEKACRDNVQFVKMRRYLRVAADGSDNIRWSKVALAKDVLAELPYQVNEYMHRK 1803
            F  K  ++Y FEE+Q +  ++  YD+    +NL     LG++ C++G V+ S G  ++        ++ +G      G   +  EE    +E++ ++  G  L K + FGK+DP+L+ +R N    +  C++TEV+KNT +P W    +    LCN D +  + + VY  D                +GE   + REL +    +   +E++NPKKKKKKK YLNSG +++ +   + E TFLD++  G ++NF VAID T SNG+ S P+SLH+M     N Y++A++AV EI+Q+YD+D+LFPA GFGA++PPD ++ HE+PLNG+ +NPYC G EGV+ AY Q+LK V+L GPT FSPVI H++R A   + G  YF+LLI++DG + D  +TK+++V  S LP+SII+VGVG  +F +M  LD D   +      A RD VQFV  R Y+    D   N   S   LAKDVLAE+P Q  +Y+  +
Sbjct:   80 FVHKFILDYFFEERQNLRFDL--YDLDSKSENLSKHDFLGQMYCTLGEVVGSPGSRME--------RSLIGIPGKNCGTVIVKAEELGNCRESVLMQFCGNKLDKKDFFGKSDPFLVFYRSNEDGTFTICHKTEVVKNTLDPVWQAFKIPVRALCNGDYDRAIKIEVYDWDRD---------GGHDYIGEFSTSYRELSK-GHTQFTVWEVLNPKKKKKKKKYLNSGTVTLLSCFIDVEVTFLDYIKGGTQINFTVAIDFTASNGNPSQPTSLHYMSPYHLNAYALALRAVGEIIQDYDSDKLFPALGFGAKLPPDGRVSHEFPLNGNPDNPYCSGIEGVLEAYYQSLKSVRLYGPTYFSPVINHVARYASLVKDGSEYFILLIISDGVISDMAQTKESIVNASSLPMSIIIVGVGPAEFDEMIELDGDEVRISSRGRFAERDIVQFVPFRDYI----DRRGNHILSMARLAKDVLAEIPDQFLQYVRSR 545          
BLAST of Copine-3 vs. Ensembl Zebrafish
Match: cpne1 (copine I [Source:ZFIN;Acc:ZDB-GENE-030131-3562])

HSP 1 Score: 311.612 bits (797), Expect = 3.366e-97
Identity = 187/501 (37.33%), Postives = 303/501 (60.48%), Query Frame = 1
Query:  325 KTER-KSGHDITFDAKLCIEYLFEEKQMIIIEIFEYD---ITQDGDNLLGEVDCSIGRVIHSGGVVLKPLEITDEFKTTLGPLSPEVGIYVEEDLTAKENIELKIRGIGLAKTEIFGKTDPYLMIFRCNNRSRYVQCYRTEVLKNTQNPDWSPIVVSYERLCNNDLNSVLCLRVYCGDGTLKESEEVDIACDQLVGEIKVTARELIQMRRMEEKQFELINPXXXXXXXSYLNSGIISVRAQKTNSEPTFLDFMFQGLELNFIVAIDLTLSNGDSSLPSSLHFMDCSLTNEYSVAIQAVLEILQEYDNDELFPAFGFGARVPPDYKICHEYPLNGDFENPYCRGAEGVIHAYQQTLKEVKLAGPTCFSPVIRHISRLAKASE---SGKHYFVLLILTDGSVDDWVETKKAVVETSYLPXXXXXXXXXXXKFSDMETLDQDFGLLM-VSNEKACRDNVQFVKMRRYLRVAADGSDNIRWSKVALAKDVLAELPYQVNEYMHRK 1803
            +TER K+  D  F  KL I+Y FE+ Q +   +++ D   +    D+ LG  + ++G+++ S  +  +PL++        G ++        E++     I ++I    L K ++FGK+DP+L  F+ +   ++   +RTEV+KN  NP W    VS    CN DLN  +  +V C D      ++ D + D ++GE   T  +L++ +     +F+ I+P+K+KKKKSY NSG+I ++  K  ++ +FLD++  G ++NF V ID T SNGD   P SLH+++ +  N+Y  AI +V +++Q+YD+D+LFPAFGFGA+VPP++++ HE+PLN +  +PYC+G EG+++AY+  L +++L GPT FSP+I H++R+A  +    +   YFVLLI+TDG + D  +T++++V +S LP+SII+VGVG   F  ME LD D G+L  ++ E A RD VQFV  +++              K ALA+ VLAE+P Q+  Y   +
Sbjct:   47 RTERVKNCQDPQFSTKLHIDYYFEKVQKLKFGVYDIDNKSVDLGDDDFLGGFEGTLGQIVSSRKLT-RPLQLKAAKPAGKGTIT-----ITAEEVKDNRAIVMEIEAKNLDKKDLFGKSDPFLEFFKQDEDGKWQLVHRTEVIKNNLNPSWKKFTVSLHTFCNGDLNKPI--KVTCYD------KDEDTSSD-MIGEFTCTTAKLMEAKD-NAVEFDCIHPEKQKKKKSYKNSGVIKIKDCKLETQYSFLDYVMGGCQINFTVGIDFTGSNGDPRSPDSLHYLNPNGVNQYLSAIWSVGQVVQDYDSDKLFPAFGFGAQVPPNFQVSHEFPLNFNPNSPYCQGVEGIVNAYRSVLPQLRLYGPTNFSPIINHVARIASGAAQQPNAAQYFVLLIITDGEITDLDQTRQSIVNSSKLPMSIIIVGVGEADFKAMEFLDGDNGVLKSITGESAVRDIVQFVPFKQFANAP----------KEALAQSVLAEVPSQLVTYFKMR 521          
BLAST of Copine-3 vs. Ensembl Xenopus
Match: acot11 (acyl-CoA thioesterase 11 [Source:Xenbase;Acc:XB-GENE-5864266])

HSP 1 Score: 326.635 bits (836), Expect = 1.598e-102
Identity = 202/488 (41.39%), Postives = 287/488 (58.81%), Query Frame = 1
Query:  358 FDAKLCIEYLFEEKQMIIIEIFEYD-----ITQDGDNLLGEVDCSIGRVIHSGGVVL-KPLEITDEFKTTLGPLSPEVGIYVEEDLTAKENIELKIRGIGLAKTEIFGKTDPYLMIFRCNNRSRYVQCYRTEVLKNTQNPDWSPIVVSYERLCNNDLNSVLCLRVYCGDGTLKESEEVDIACDQLVGEIKVTARELIQMRRMEEKQFELINPXXXXXXXSYLNSGIISVRAQKTNSEPTFLDFMFQGLELNFIVAIDLTLSNGDSSLPSSLHFMDCSLTNEYSVAIQAVLEILQEYDNDELFPAFGFGARVPPDYKICHEYPLNGDFENPYCRGAEGVIHAYQQTLKEVKLAGPTCFSPVIRHISRLAKASESGKHYFVLLILTDGSVDDWVETKKAVVETSYLPXXXXXXXXXXXKFSDMETLDQDFGLLMVSNEKACRDNVQFVKMRRYLRVAADGSDNIRWSKVALAKDVLAELPYQVNEYMHRK 1803
            F  K  ++Y FEEKQ +  ++F  D     I++  D  LG+  C++G VI S    L KPL          G     + +  EE    ++ + +++    L K + FGK+DP+L+ +R N    +  C++TEV+KNT NP W P  +    LCN D +  + + VY  D                +GE   + REL + +  +   +E++NPKKK KKK Y+NSG +++ + K  SE TF+D++  G +LNF VAID T SNG+ S P+SLH+M+    N Y +A++AV EI+Q+YD+D+LFPA+GFGA++PPD KI HE+ LNGD ENP C G +GV+ AY ++L+ V+L GPT F+ VI  ++R A     G  Y+VLLI+TDG + D V+TK+A+V  S LP+SII+VGVG  +F  ME LD D   +      A RD VQFV  R Y+    D S N   S   LAKDVLAE+P Q   YM  +
Sbjct:   70 FVRKFVLDYFFEEKQNLRFDVFNVDSRSCNISKHKD-FLGQAFCTLGEVIGSPRSRLEKPL------TGIPGKKCGTIILSAEELSNCRDIVTMQLCANKLDKKDFFGKSDPFLVFYRSNEDGTFTICHKTEVIKNTLNPVWQPFTIPVRALCNGDYDRTVKVDVYDWDRG---------GSHDFIGEFTTSYRELSRGQS-QFSVYEVLNPKKKCKKKKYINSGTVTLLSFKAESEYTFVDYIKGGTQLNFTVAIDFTASNGNPSQPTSLHYMNPYQLNAYGMALKAVGEIIQDYDSDKLFPAYGFGAKIPPDGKISHEFALNGDIENPNCVGIQGVLEAYFKSLRTVQLYGPTNFASVINQVARAAGDVTDGSQYYVLLIITDGVISDMVQTKEAIVNASSLPMSIIIVGVGPAEFDAMEELDGDEVRVSSRGRFAERDIVQFVPFRDYV----DRSGNQVLSMARLAKDVLAEIPEQFLSYMKSR 536          
BLAST of Copine-3 vs. Ensembl Xenopus
Match: acot11 (acyl-CoA thioesterase 11 [Source:Xenbase;Acc:XB-GENE-5864266])

HSP 1 Score: 317.005 bits (811), Expect = 2.250e-99
Identity = 199/486 (40.95%), Postives = 279/486 (57.41%), Query Frame = 1
Query:  358 FDAKLCIEYLFEEKQMIIIEIFEYDITQ---DGDNLLGEVDCSIGRVIHSGGVVL-KPLEITDEFKTTLGPLSPEVGIYVEEDLTAKENIELKIRGIGLAKTEIFGKTDPYLMIFRCNNRSRYVQCYRTEVLKNTQNPDWSPIVVSYERLCNNDLNSVLCLRVYCGDGTLKESEEVDIACDQLVGEIKVTARELIQMRRMEEKQFELINPXXXXXXXSYLNSGIISVRAQKTNSEPTFLDFMFQGLELNFIVAIDLTLSNGDSSLPSSLHFMDCSLTNEYSVAIQAVLEILQEYDNDELFPAFGFGARVPPDYKICHEYPLNGDFENPYCRGAEGVIHAYQQTLKEVKLAGPTCFSPVIRHISRLAKASESGKHYFVLLILTDGSVDDWVETKKAVVETSYLPXXXXXXXXXXXKFSDMETLDQDFGLLMVSNEKACRDNVQFVKMRRYLRVAADGSDNIRWSKVALAKDVLAELPYQVNEYMHRK 1803
            F  K  ++Y FEEKQ +  ++F  D         + LG+  C++G VI S    L KPL          G     + +  EE    ++ + +++    L K + FGK+DP+L+ +R N    +  C++TEV+KNT NP W P  +    LCN D +  + + VY  D                +GE   + REL + +  +   +E++NPKKK KKK Y+NSG ++      +S  TFL F F   +LNF VAID T SNG+ S P+SLH+M+    N Y +A++AV EI+Q+YD+D+LFPA+GFGA++PPD KI HE+ LNGD ENP C G +GV+ AY ++L+ V+L GPT F+ VI  ++R A     G  Y+VLLI+TDG + D V+TK+A+V  S LP+SII+VGVG  +F  ME LD D   +      A RD VQFV  R Y+    D S N   S   LAKDVLAE+P Q   YM  +
Sbjct:   36 FVRKFVLDYFFEEKQNLRFDVFNVDSRSCNISKHDFLGQAFCTLGEVIGSPRSRLEKPL------TGIPGKKCGTIILSAEELSNCRDIVTMQLCANKLDKKDFFGKSDPFLVFYRSNEDGTFTICHKTEVIKNTLNPVWQPFTIPVRALCNGDYDRTVKVDVYDWDRG---------GSHDFIGEFTTSYRELSRGQS-QFSVYEVLNPKKKCKKKKYINSGTVT-EELDGDSAITFLSFFFSRTQLNFTVAIDFTASNGNPSQPTSLHYMNPYQLNAYGMALKAVGEIIQDYDSDKLFPAYGFGAKIPPDGKISHEFALNGDIENPNCVGIQGVLEAYFKSLRTVQLYGPTNFASVINQVARAAGDVTDGSQYYVLLIITDGVISDMVQTKEAIVNASSLPMSIIIVGVGPAEFDAMEELDGDEVRVSSRGRFAERDIVQFVPFRDYV----DRSGNQVLSMARLAKDVLAEIPEQFLSYMKSR 500          
BLAST of Copine-3 vs. Ensembl Xenopus
Match: cpne9 (copine family member IX [Source:NCBI gene;Acc:100125077])

HSP 1 Score: 318.546 bits (815), Expect = 3.325e-99
Identity = 191/500 (38.20%), Postives = 288/500 (57.60%), Query Frame = 1
Query:  358 FDAKLCIEYLFEEKQMIIIEIFEYDITQ---DGDNLLGEVDCSIGRVIHSGGVVLKPLEI------------TDEFKTTLGPLSPEVGIYV---EEDLTAKENIELKIRGIGLAKTEIFGKTDPYLMIFRCNNRSRYVQCYRTEVLKNTQNPDWSPIVVSYERLCNNDLNSVLCLRVYCGDGTLKESEEVDIACDQLVGEIKVTARELIQMRRMEEKQFELINPXXXXXXXSYLNSGIISVRAQKTNSEPTFLDFMFQGLELNFIVAIDLTLSNGDSSLPSSLHFMDCSLTNEYSVAIQAVLEILQEYDNDELFPAFGFGARVPPDYKICHEYPLNGDFENPYCRGAEGVIHAYQQTLKEVKLAGPTCFSPVIRHISRLAKASESGKHYFVLLILTDGSVDDWVETKKAVVETSYLPXXXXXXXXXXXKFSDMETLDQDFGLLMVSNEKACRDNVQFVKMRRYLRVAADGSDNIRWSKVALAKDVLAELPYQVNEYMHRK 1803
            F  K  ++Y FEEKQ +  ++++ D         + LG+  C++G ++ S G  L+   I            + +  +  G  S + GI +   EE    ++   ++     L K + FGK+DP+++ +R N    Y  C++TE +KNT +P W    +    LCN D +  + + VY  D                +GE   + REL + +  +   +E+INP+KK KKK Y+NSG +++ +    SE TFLD++  G ++NF VAID T SNG+ S  +SLH+M+    N Y++A++AV EI+Q+YD+D+ FPA GFGA++PPD ++ HE+PLNG  ENP C G EG++ AY ++LK V+L GPT F+PV+  ++R A A + G HYFVLLI+TDG + D  +TK+A+V  + LP+SII+VGVG  +F  M  LD D   +    + A RD VQFV  R Y+    D + N   S   LAKDVLAE+P Q+  YM  +
Sbjct:   70 FVRKFVLDYFFEEKQNLRFDLYDVDAKSPDLSKHDFLGQCFCTLGEIVGSAGSRLEKSLIIGQNAPNSRSGRSTQSMSNGGIPSKKCGIIIISAEELSNCRDIATVQFSAHKLDKKDFFGKSDPFMVFYRSNEDGTYTICHKTEYVKNTLSPVWQKFSIPVRGLCNGDYDRTIKVEVYDWDRD---------GSHDFIGEFSTSYRELSKGQS-QFNIYEVINPRKKIKKKKYINSGTVTLLSFSVESEYTFLDYIKGGTQINFTVAIDFTASNGNPSQSTSLHYMNPYQLNAYALALKAVGEIIQDYDSDKRFPALGFGAKLPPDGRVSHEFPLNGSIENPQCNGIEGILEAYHKSLKSVQLYGPTNFAPVVNRVARFAAAVQDGSHYFVLLIITDGVISDMSQTKEAIVNAAMLPMSIIIVGVGQAEFDAMVELDGDDVRISSRGKLAERDIVQFVPFRDYV----DRTGNHVLSMARLAKDVLAEIPDQLISYMKAR 555          
BLAST of Copine-3 vs. Ensembl Xenopus
Match: acot11 (acyl-CoA thioesterase 11 [Source:Xenbase;Acc:XB-GENE-5864266])

HSP 1 Score: 314.309 bits (804), Expect = 1.717e-98
Identity = 198/483 (40.99%), Postives = 276/483 (57.14%), Query Frame = 1
Query:  358 FDAKLCIEYLFEEKQMIIIEIFEYDITQDGDNLLGEVDCSIGRVIHSGGVVL-KPLEITDEFKTTLGPLSPEVGIYVEEDLTAKENIELKIRGIGLAKTEIFGKTDPYLMIFRCNNRSRYVQCYRTEVLKNTQNPDWSPIVVSYERLCNNDLNSVLCLRVYCGDGTLKESEEVDIACDQLVGEIKVTARELIQMRRMEEKQFELINPXXXXXXXSYLNSGIISVRAQKTNSEPTFLDFMFQGLELNFIVAIDLTLSNGDSSLPSSLHFMDCSLTNEYSVAIQAVLEILQEYDNDELFPAFGFGARVPPDYKICHEYPLNGDFENPYCRGAEGVIHAYQQTLKEVKLAGPTCFSPVIRHISRLAKASESGKHYFVLLILTDGSVDDWVETKKAVVETSYLPXXXXXXXXXXXKFSDMETLDQDFGLLMVSNEKACRDNVQFVKMRRYLRVAADGSDNIRWSKVALAKDVLAELPYQVNEYMHRK 1803
            F  K  ++Y FEEKQ +             D+ LG+  C++G VI S    L KPL          G     + +  EE    ++ + +++    L K + FGK+DP+L+ +R N    +  C++TEV+KNT NP W P  +    LCN D +  + + VY  D                +GE   + REL + +  +   +E++NPKKK KKK Y+NSG ++      +S  TFL F F   +LNF VAID T SNG+ S P+SLH+M+    N Y +A++AV EI+Q+YD+D+LFPA+GFGA++PPD KI HE+ LNGD ENP C G +GV+ AY ++L+ V+L GPT F+ VI  ++R A     G  Y+VLLI+TDG + D V+TK+A+V  S LP+SII+VGVG  +F  ME LD D   +      A RD VQFV  R Y+    D S N   S   LAKDVLAE+P Q   YM  +
Sbjct:   36 FVRKFVLDYFFEEKQNLRF-----------DDFLGQAFCTLGEVIGSPRSRLEKPL------TGIPGKKCGTIILSAEELSNCRDIVTMQLCANKLDKKDFFGKSDPFLVFYRSNEDGTFTICHKTEVIKNTLNPVWQPFTIPVRALCNGDYDRTVKVDVYDWDRG---------GSHDFIGEFTTSYRELSRGQS-QFSVYEVLNPKKKCKKKKYINSGTVT-EELDGDSAITFLSFFFSRTQLNFTVAIDFTASNGNPSQPTSLHYMNPYQLNAYGMALKAVGEIIQDYDSDKLFPAYGFGAKIPPDGKISHEFALNGDIENPNCVGIQGVLEAYFKSLRTVQLYGPTNFASVINQVARAAGDVTDGSQYYVLLIITDGVISDMVQTKEAIVNASSLPMSIIIVGVGPAEFDAMEELDGDEVRVSSRGRFAERDIVQFVPFRDYV----DRSGNQVLSMARLAKDVLAEIPEQFLSYMKSR 486          
BLAST of Copine-3 vs. Ensembl Xenopus
Match: cpne9 (copine family member IX [Source:NCBI gene;Acc:100125077])

HSP 1 Score: 316.235 bits (809), Expect = 2.234e-98
Identity = 192/502 (38.25%), Postives = 288/502 (57.37%), Query Frame = 1
Query:  358 FDAKLCIEYLFEEKQ-----MIIIEIFEYDITQDGDNLLGEVDCSIGRVIHSGGVVLKPLEI------------TDEFKTTLGPLSPEVGIYV---EEDLTAKENIELKIRGIGLAKTEIFGKTDPYLMIFRCNNRSRYVQCYRTEVLKNTQNPDWSPIVVSYERLCNNDLNSVLCLRVYCGDGTLKESEEVDIACDQLVGEIKVTARELIQMRRMEEKQFELINPXXXXXXXSYLNSGIISVRAQKTNSEPTFLDFMFQGLELNFIVAIDLTLSNGDSSLPSSLHFMDCSLTNEYSVAIQAVLEILQEYDNDELFPAFGFGARVPPDYKICHEYPLNGDFENPYCRGAEGVIHAYQQTLKEVKLAGPTCFSPVIRHISRLAKASESGKHYFVLLILTDGSVDDWVETKKAVVETSYLPXXXXXXXXXXXKFSDMETLDQDFGLLMVSNEKACRDNVQFVKMRRYLRVAADGSDNIRWSKVALAKDVLAELPYQVNEYMHRK 1803
            F  K  ++Y FEEKQ     +  I  F+ + +    + LG+  C++G ++ S G  L+   I            + +  +  G  S + GI +   EE    ++   ++     L K + FGK+DP+++ +R N    Y  C++TE +KNT +P W    +    LCN D +  + + VY  D                +GE   + REL + +  +   +E+INP+KK KKK Y+NSG +++ +    SE TFLD++  G ++NF VAID T SNG+ S  +SLH+M+    N Y++A++AV EI+Q+YD+D+ FPA GFGA++PPD ++ HE+PLNG  ENP C G EG++ AY ++LK V+L GPT F+PV+  ++R A A + G HYFVLLI+TDG + D  +TK+A+V  + LP+SII+VGVG  +F  M  LD D   +    + A RD VQFV  R Y+    D + N   S   LAKDVLAE+P Q+  YM  +
Sbjct:   65 FVRKFVLDYFFEEKQNLRFDLFAITYFDLNFSLFLFDFLGQCFCTLGEIVGSAGSRLEKSLIIGQNAPNSRSGRSTQSMSNGGIPSKKCGIIIISAEELSNCRDIATVQFSAHKLDKKDFFGKSDPFMVFYRSNEDGTYTICHKTEYVKNTLSPVWQKFSIPVRGLCNGDYDRTIKVEVYDWDRD---------GSHDFIGEFSTSYRELSKGQS-QFNIYEVINPRKKIKKKKYINSGTVTLLSFSVESEYTFLDYIKGGTQINFTVAIDFTASNGNPSQSTSLHYMNPYQLNAYALALKAVGEIIQDYDSDKRFPALGFGAKLPPDGRVSHEFPLNGSIENPQCNGIEGILEAYHKSLKSVQLYGPTNFAPVVNRVARFAAAVQDGSHYFVLLIITDGVISDMSQTKEAIVNAAMLPMSIIIVGVGQAEFDAMVELDGDDVRISSRGKLAERDIVQFVPFRDYV----DRTGNHVLSMARLAKDVLAEIPDQLISYMKAR 552          
BLAST of Copine-3 vs. Ensembl Mouse
Match: Cpne8 (copine VIII [Source:MGI Symbol;Acc:MGI:1914121])

HSP 1 Score: 319.701 bits (818), Expect = 9.338e-100
Identity = 194/490 (39.59%), Postives = 289/490 (58.98%), Query Frame = 1
Query:  358 FDAKLCIEYLFEEKQMIIIEIFEYDITQDGDNL-----LGEVDCSIGRVIHSGGVVLKPLEITDEFKTTLGPLSPEVGIYV---EEDLTAKENIELKIRGIGLAKTEIFGKTDPYLMIFRCNNRSRYVQCYRTEVLKNTQNPDWSPIVVSYERLCNNDLNSVLCLRVYCGDGTLKESEEVDIACDQLVGEIKVTARELIQMRRMEEKQFELINPXXXXXXXSYLNSGIISVRAQKTNSEPTFLDFMFQGLELNFIVAIDLTLSNGDSSLPSSLHFMDCSLTNEYSVAIQAVLEILQEYDNDELFPAFGFGARVPPDYKICHEYPLNGDFENPYCRGAEGVIHAYQQTLKEVKLAGPTCFSPVIRHISRLAKASESGKHYFVLLILTDGSVDDWVETKKAVVETSYLPXXXXXXXXXXXKFSDMETLDQDFGLLMVSNEKACRDNVQFVKMRRYLRVAADGSDNIRWSKVALAKDVLAELPYQVNEYMHRK 1803
            F  K  ++Y FEE++ +  ++  YD+     NL     LG+V C++G ++ S G  L+        K  +G    + G  +   EE    ++ + ++     L K + FGK+DP+L+ +R N    +  C++TEV+KNT NP W    +S   LCN D +  + + VY  D                +GE   + REL + +  +   +E++NPKKK KKK Y NSG +++ +    +E +FLD++  G ++NF VAID T SNG+ + P+SLH+M+    N Y +A++AV EI+Q+YD+D++FPA GFGA++PPD +I HE+ LNG+ +NPYC G EGV+ AY ++LK V+L GPT F+PVI H++R A + + G  YFVLLI+TDG + D  +TK+++V  S LP+SII+VGVG  +F  M  LD D   +    + A RD VQFV  R Y+    D S N   S   LAKDVLAE+P Q   YM  +
Sbjct:   90 FVRKFILDYFFEERENLRFDL--YDVDSKSPNLSKHDFLGQVFCTLGEIVGSQGSRLE--------KPIVGIPGRKCGTIILTAEELNCCRDAVLMQFCANKLDKKDFFGKSDPFLVFYRSNEDGSFTICHKTEVVKNTLNPVWQAFKISVRALCNGDYDRTIKVEVYDWDRD---------GSHDFIGEFTTSYRELARGQS-QFNVYEVVNPKKKGKKKKYTNSGTVTLLSFLVETEVSFLDYIKGGTQINFTVAIDFTASNGNPAQPTSLHYMNPYQLNAYGMALKAVGEIVQDYDSDKMFPALGFGAKLPPDGRISHEFALNGNPQNPYCDGIEGVMEAYYRSLKSVQLYGPTNFAPVINHVARYASSVKDGSQYFVLLIVTDGVISDMAQTKESIVNASKLPMSIIIVGVGPAEFDAMVELDGDDVRVSSRGKYAERDIVQFVPFRDYI----DRSGNHILSMARLAKDVLAEIPEQFLSYMRAR 555          
BLAST of Copine-3 vs. Ensembl Mouse
Match: Cpne5 (copine V [Source:MGI Symbol;Acc:MGI:2385908])

HSP 1 Score: 316.62 bits (810), Expect = 2.149e-98
Identity = 193/497 (38.83%), Postives = 284/497 (57.14%), Query Frame = 1
Query:  358 FDAKLCIEYLFEEKQMIIIEIFEYDITQ---DGDNLLGEVDCSIGRVIHSGGVVL-KPLEI-TDEFKTTLGPLSPEVG-------------IYVEEDLTAKENIELKIRGIGLAKTEIFGKTDPYLMIFRCNNRSRYVQCYRTEVLKNTQNPDWSPIVVSYERLCNNDLNSVLCLRVYCGDGTLKESEEVDIACDQLVGEIKVTARELIQMRRMEEKQFELINPXXXXXXXSYLNSGIISVRAQKTNSEPTFLDFMFQGLELNFIVAIDLTLSNGDSSLPSSLHFMDCSLTNEYSVAIQAVLEILQEYDNDELFPAFGFGARVPPDYKICHEYPLNGDFENPYCRGAEGVIHAYQQTLKEVKLAGPTCFSPVIRHISRLAKASESGKHYFVLLILTDGSVDDWVETKKAVVETSYLPXXXXXXXXXXXKFSDMETLDQDFGLLMVSNEKACRDNVQFVKMRRYLRVAADGSDNIRWSKVALAKDVLAELPYQVNEYM 1794
            F  K  ++Y FEEKQ +  ++++ D         + LG+  C++G ++ S G  L KPL I T    +  G   P V              +  EE    ++   ++     L K + FGK+DP+L+ +R N    +  C++TEV+KNT NP W    +    LCN D +  + + VY  D                +GE   + REL + +  +   +E+INPKKK KKK Y+NSG +++ +    SE TFLD++  G ++NF VAID T SNG+ S  +SLH+M     N Y++A+ AV EI+Q YD+D++FPA GFGA++PPD ++ HE+PLNG+ ENP C G +G++ AY  +L+ V+L GPT F+PV+ H++R A A + G  Y VLLI+TDG + D  +TK+A+V  + LP+SII+VGVG  +F  M  LD D   +    + A RD VQFV  R Y+    D + N   S   LA+DVLAE+P Q+  YM
Sbjct:   76 FVRKFIVDYFFEEKQNLRFDLYDVDSKSPDLSKHDFLGQAFCTLGEIVGSSGSRLEKPLTIGTFSLNSRTGKPMPAVSNGGVPGKKCGTIILSAEELSNCRDVATMQFCANKLDKKDFFGKSDPFLVFYRSNEDGTFTICHKTEVMKNTLNPVWQTFSIPVRALCNGDYDRTIKVEVYDWDRD---------GSHDFIGEFTTSYRELARGQS-QFNIYEVINPKKKMKKKKYVNSGTVTLLSFAVESESTFLDYIKGGTQINFTVAIDFTASNGNPSQSTSLHYMSPYQLNAYALALTAVGEIIQHYDSDKMFPALGFGAKLPPDGRVSHEFPLNGNQENPSCCGIDGILEAYHSSLRTVQLYGPTNFAPVVTHVARNAAAVQDGSQYSVLLIITDGVISDMAQTKEAIVNAAKLPMSIIIVGVGQAEFDAMVELDGDDVRISSRGKLAERDIVQFVPFRDYV----DRTGNHVLSMARLARDVLAEIPDQLVSYM 558          
BLAST of Copine-3 vs. Ensembl Mouse
Match: Cpne9 (copine family member IX [Source:MGI Symbol;Acc:MGI:2443052])

HSP 1 Score: 311.227 bits (796), Expect = 7.338e-97
Identity = 191/487 (39.22%), Postives = 283/487 (58.11%), Query Frame = 1
Query:  358 FDAKLCIEYLFEEKQMIIIEIFEYD----ITQDGDNLLGEVDCSIGRVIHS-GGVVLKPLEITDEFKTTLGPLSPEVGIYVEEDLTAKENIELKIRGIGLAKTEIFGKTDPYLMIFRCNNRSRYVQCYRTEVLKNTQNPDWSPIVVSYERLCNNDLNSVLCLRVYCGDGTLKESEEVDIACDQLVGEIKVTARELIQMRRMEEKQFELINPXXXXXXXSYLNSGIISVRAQKTNSEPTFLDFMFQGLELNFIVAIDLTLSNGDSSLPSSLHFMDCSLTNEYSVAIQAVLEILQEYDNDELFPAFGFGARVPPDYKICHEYPLNGDFENPYCRGAEGVIHAYQQTLKEVKLAGPTCFSPVIRHISRLAKASESGKHYFVLLILTDGSVDDWVETKKAVVETSYLPXXXXXXXXXXXKFSDMETLDQDFGLLMVSNEKACRDNVQFVKMRRYLRVAADGSDNIRWSKVALAKDVLAELPYQVNEYMHRK 1803
            F  K  ++Y FEEKQ +  +++  D    I++  D  LG+   ++G VI   G  V +PL          G     + +  EE    ++   +++    L K + FGK+DP+L+ +R N    +  C++TEV+KNT NP W P  +    LCN D +  + + VY  D                +GE   + REL + +  +   +E++NP+KK KKK Y NSG +++ +   +SE TF+D++  G +LNF VAID T SNG+   P+SLH+M     + Y++A++AV EI+Q+YD+D+LFPA+GFGA++PP+ +I H++PLN + E+P C G EGV+ +Y Q+L+ V+L GPT F+PVI  ++R A     G  Y+VLLI+TDG + D  +TK+A+V  S LP+SII+VGVG   F  ME LD D   +      A RD VQFV  R Y+    D S N   S   LAKDVLAE+P Q+  YM  +
Sbjct:   67 FVRKFVLDYFFEEKQNLRFDVYNVDSKANISKPKD-FLGQAFLALGEVIGGQGSRVERPL------TGVPGKKCGTILLTAEELSNCRDIATMQLCANKLDKKDFFGKSDPFLVFYRSNEDGTFTICHKTEVVKNTLNPVWQPFSIPVRALCNGDYDRTVKIDVYDWDRD---------GSHDFIGEFTTSYRELSKAQN-QFTVYEVLNPRKKCKKKKYTNSGTVTLLSFSVDSEFTFVDYIKGGTQLNFTVAIDFTASNGNPLQPTSLHYMSPYQLSAYAMALKAVGEIIQDYDSDKLFPAYGFGAKLPPEGRISHQFPLNNNDEDPNCAGIEGVLESYFQSLRTVQLYGPTYFAPVINQVARAAAKISDGSQYYVLLIITDGVISDMTQTKEAIVSASSLPMSIIIVGVGPAMFEAMEELDGDDVRVSSRGRYAERDIVQFVPFRDYV----DRSGNQVLSMARLAKDVLAEIPEQLLSYMRTR 532          
BLAST of Copine-3 vs. Ensembl Mouse
Match: Cpne2 (copine II [Source:MGI Symbol;Acc:MGI:2387578])

HSP 1 Score: 296.59 bits (758), Expect = 2.334e-91
Identity = 187/495 (37.78%), Postives = 277/495 (55.96%), Query Frame = 1
Query:  355 TFDAKLCIEYLFEEKQMIIIEIFEYDITQ---DGDNLLGEVDCSIGRVIHSGGVVLKPLEITDEFKTTLGPLSPEVGIYVEEDLTAKENIELKIRGIGLAKTEIFGKTDPYLMIFRCNNRSRYVQCYRTEVLKNTQNPDWSPIVVSYERLCNNDLNSVLCLRVYCGDGTLKESEEVDIACDQLVGEIKVTARELIQMRRMEEKQFELINPXXXXXXXSYLNSGIISVRAQKTNSEPTFLDFMFQGLELNFIVAIDLTLSNGDSSLPSSLHFMDCSLTNEYSVAIQAVLEILQEYDNDELFPAFGFGARVPPDYKICHEYPLNGDFENPYCRGAEGVIHAYQQTLKEVKLAGPTCFSPVIRHISRL--AKASESGKHYFVLLILTDGSVDDWVETKKAVVETSYLPXXXXXXXXXXXKFSDMETLDQDFGLLMV-SNEKACRDNVQFVKMRRYLRVAADGSDNIRWSKVALAKDVLAELPYQVNEYM-HRKTKLTN 1818
             F  K  ++Y FEE Q +   +F+ D +    D  + LG+  CS+G ++ S  +    L + D+      P    V     ++L+    I L + G  L K ++FGK+DP+L  ++  +  +++  +RTEV+K T +P W P  V    LC+ DL   + +  Y  D                +GE + +  ++ + R     + E INPKK++KKKSY NSGII +R+ K +   +FLD++  G +L F V ID T SNG+   PSSLH+++   TNEY  AI AV +I+Q+YD+D++FPA GFGA++PPD+K+ HE+ +N +  NP+C G +G+  AY   L  ++  GPT FSP++ H++R       +    YF+LLI+TDG + D  ET+ AVV+ S LP+SII+VGVG   F+ ME LD D   L   + E+A RD VQFV  R +   A          K  LAK VLAELP QV +Y  H+    TN
Sbjct:   74 AFSKKFVLDYHFEEVQKLKFALFDQDKSSAQLDEHDFLGQFSCSLGTIVSSKKITRPLLLMNDK------PAGKGVITIAAQELSDNRVITLSLAGRKLDKKDLFGKSDPFLEFYKPGDDGKWMLVHRTEVIKYTLDPVWKPFTVPLVSLCDGDLEKPIQVMCYDYDSN---------GGHDFIGEFQTSVLQMSEARDGVPLEIECINPKKQRKKKSYKNSGIIILRSCKIHRNYSFLDYILGGCQLMFTVGIDFTASNGNPLDPSSLHYINPMGTNEYLSAIWAVGQIIQDYDSDKMFPALGFGAQLPPDWKVSHEFAINFNPTNPFCSGVDGIAQAYSACLPHIRFYGPTNFSPIVNHVARFAAQATQQQTATYFILLIITDGVISDMEETRHAVVQASKLPMSIIIVGVGNADFAAMEFLDGDNRRLRSHTGEEAARDIVQFVPFREFRNAA----------KETLAKAVLAELPQQVVQYFKHKNLPPTN 543          
BLAST of Copine-3 vs. Ensembl Mouse
Match: Cpne2 (copine II [Source:MGI Symbol;Acc:MGI:2387578])

HSP 1 Score: 296.204 bits (757), Expect = 3.358e-91
Identity = 188/496 (37.90%), Postives = 279/496 (56.25%), Query Frame = 1
Query:  355 TFDAKLCIEYLFEEKQMIIIEIFEYDITQ---DGDNLLGEVDCSIGRVIHSGGVVLKPLEITDEFKTTLGPLSPEVGIYVEEDLTAKENIELKIRGIGLAKTEIFGKTDPYLMIFRCNNRSRYVQCYRTEVLKNTQNPDWSPIVVSYERLCNNDLNSVLCLRVYCGDGTLKESEEVDIACDQLVGEIKVTARELIQMRRMEEKQFELINPXXXXXXXSYLNSGIISVRAQKTNSEPTFLDFMFQGLELNFIVAIDLTLSNGDSSLPSSLHFMDCSLTNEYSVAIQAVLEILQEYDNDELFPAFGFGARVPPDYKICHEYPLNGDFENPYCRGAEGVIHAYQQTLKEVKLAGPTCFSPVIRHISRL---AKASESGKHYFVLLILTDGSVDDWVETKKAVVETSYLPXXXXXXXXXXXKFSDMETLDQDFGLLMV-SNEKACRDNVQFVKMRRYLRVAADGSDNIRWSKVALAKDVLAELPYQVNEYM-HRKTKLTN 1818
             F  K  ++Y FEE Q +   +F+ D +    D  + LG+  CS+G ++ S  +    L + D+      P    V     ++L+    I L + G  L K ++FGK+DP+L  ++  +  +++  +RTEV+K T +P W P  V    LC+ DL   + +  Y  D                +GE + +  ++ + R     + E INPKK++KKKSY NSGII +R+ K +   +FLD++  G +L F V ID T SNG+   PSSLH+++   TNEY  AI AV +I+Q+YD+D++FPA GFGA++PPD+K+ HE+ +N +  NP+C G +G+  AY   L  ++  GPT FSP++ H++R    A   ++   YF+LLI+TDG + D  ET+ AVV+ S LP+SII+VGVG   F+ ME LD D   L   + E+A RD VQFV  R +   A          K  LAK VLAELP QV +Y  H+    TN
Sbjct:   74 AFSKKFVLDYHFEEVQKLKFALFDQDKSSAQLDEHDFLGQFSCSLGTIVSSKKITRPLLLMNDK------PAGKGVITIAAQELSDNRVITLSLAGRKLDKKDLFGKSDPFLEFYKPGDDGKWMLVHRTEVIKYTLDPVWKPFTVPLVSLCDGDLEKPIQVMCYDYDSN---------GGHDFIGEFQTSVLQMSEARDGVPLEIECINPKKQRKKKSYKNSGIIILRSCKIHRNYSFLDYILGGCQLMFTVGIDFTASNGNPLDPSSLHYINPMGTNEYLSAIWAVGQIIQDYDSDKMFPALGFGAQLPPDWKVSHEFAINFNPTNPFCSGVDGIAQAYSACLPHIRFYGPTNFSPIVNHVARFAAQATQQQTATQYFILLIITDGVISDMEETRHAVVQASKLPMSIIIVGVGNADFAAMEFLDGDNRRLRSHTGEEAARDIVQFVPFREFRNAA----------KETLAKAVLAELPQQVVQYFKHKNLPPTN 544          
BLAST of Copine-3 vs. UniProt/SwissProt
Match: sp|Q86YQ8|CPNE8_HUMAN (Copine-8 OS=Homo sapiens OX=9606 GN=CPNE8 PE=1 SV=2)

HSP 1 Score: 320.087 bits (819), Expect = 3.026e-99
Identity = 194/490 (39.59%), Postives = 289/490 (58.98%), Query Frame = 1
Query:  358 FDAKLCIEYLFEEKQMIIIEIFEYDITQDGDNL-----LGEVDCSIGRVIHSGGVVLKPLEITDEFKTTLGPLSPEVGIYV---EEDLTAKENIELKIRGIGLAKTEIFGKTDPYLMIFRCNNRSRYVQCYRTEVLKNTQNPDWSPIVVSYERLCNNDLNSVLCLRVYCGDGTLKESEEVDIACDQLVGEIKVTARELIQMRRMEEKQFELINPXXXXXXXSYLNSGIISVRAQKTNSEPTFLDFMFQGLELNFIVAIDLTLSNGDSSLPSSLHFMDCSLTNEYSVAIQAVLEILQEYDNDELFPAFGFGARVPPDYKICHEYPLNGDFENPYCRGAEGVIHAYQQTLKEVKLAGPTCFSPVIRHISRLAKASESGKHYFVLLILTDGSVDDWVETKKAVVETSYLPXXXXXXXXXXXKFSDMETLDQDFGLLMVSNEKACRDNVQFVKMRRYLRVAADGSDNIRWSKVALAKDVLAELPYQVNEYMHRK 1803
            F  K  ++Y FEE++ +  ++  YD+     NL     LG+V C++G ++ S G  L+        K  +G    + G  +   EE    ++ + ++     L K + FGK+DP+L+ +R N    +  C++TEV+KNT NP W    +S   LCN D +  + + VY  D                +GE   + REL + +  +   +E++NPKKK KKK Y NSG +++ +    +E +FLD++  G ++NF VAID T SNG+ + P+SLH+M+    N Y +A++AV EI+Q+YD+D++FPA GFGA++PPD +I HE+ LNG+ +NPYC G EGV+ AY ++LK V+L GPT F+PVI H++R A + + G  YFVLLI+TDG + D  +TK+++V  S LP+SII+VGVG  +F  M  LD D   +    + A RD VQFV  R Y+    D S N   S   LAKDVLAE+P Q   YM  +
Sbjct:   77 FVRKFILDYFFEERENLRFDL--YDVDSKSPNLSKHDFLGQVFCTLGEIVGSQGSRLE--------KPIVGIPGKKCGTIILTAEELNCCRDAVLMQFCANKLDKKDFFGKSDPFLVFYRSNEDGSFTICHKTEVVKNTLNPVWQAFKISVRALCNGDYDRTIKVEVYDWDRD---------GSHDFIGEFTTSYRELSRGQS-QFNVYEVVNPKKKGKKKKYTNSGTVTLLSFLVETEVSFLDYIKGGTQINFTVAIDFTASNGNPAQPTSLHYMNPYQLNAYGMALKAVGEIVQDYDSDKMFPALGFGAKLPPDGRISHEFALNGNPQNPYCDGIEGVMEAYYRSLKSVQLYGPTNFAPVINHVARYASSVKDGSQYFVLLIVTDGVISDMAQTKESIVNASKLPMSIIIVGVGPAEFDAMVELDGDDVRVSSRGKYAERDIVQFVPFRDYI----DRSGNHILSMARLAKDVLAEIPEQFLSYMRAR 542          
BLAST of Copine-3 vs. UniProt/SwissProt
Match: sp|Q9DC53|CPNE8_MOUSE (Copine-8 OS=Mus musculus OX=10090 GN=Cpne8 PE=2 SV=3)

HSP 1 Score: 319.701 bits (818), Expect = 6.532e-99
Identity = 194/490 (39.59%), Postives = 289/490 (58.98%), Query Frame = 1
Query:  358 FDAKLCIEYLFEEKQMIIIEIFEYDITQDGDNL-----LGEVDCSIGRVIHSGGVVLKPLEITDEFKTTLGPLSPEVGIYV---EEDLTAKENIELKIRGIGLAKTEIFGKTDPYLMIFRCNNRSRYVQCYRTEVLKNTQNPDWSPIVVSYERLCNNDLNSVLCLRVYCGDGTLKESEEVDIACDQLVGEIKVTARELIQMRRMEEKQFELINPXXXXXXXSYLNSGIISVRAQKTNSEPTFLDFMFQGLELNFIVAIDLTLSNGDSSLPSSLHFMDCSLTNEYSVAIQAVLEILQEYDNDELFPAFGFGARVPPDYKICHEYPLNGDFENPYCRGAEGVIHAYQQTLKEVKLAGPTCFSPVIRHISRLAKASESGKHYFVLLILTDGSVDDWVETKKAVVETSYLPXXXXXXXXXXXKFSDMETLDQDFGLLMVSNEKACRDNVQFVKMRRYLRVAADGSDNIRWSKVALAKDVLAELPYQVNEYMHRK 1803
            F  K  ++Y FEE++ +  ++  YD+     NL     LG+V C++G ++ S G  L+        K  +G    + G  +   EE    ++ + ++     L K + FGK+DP+L+ +R N    +  C++TEV+KNT NP W    +S   LCN D +  + + VY  D                +GE   + REL + +  +   +E++NPKKK KKK Y NSG +++ +    +E +FLD++  G ++NF VAID T SNG+ + P+SLH+M+    N Y +A++AV EI+Q+YD+D++FPA GFGA++PPD +I HE+ LNG+ +NPYC G EGV+ AY ++LK V+L GPT F+PVI H++R A + + G  YFVLLI+TDG + D  +TK+++V  S LP+SII+VGVG  +F  M  LD D   +    + A RD VQFV  R Y+    D S N   S   LAKDVLAE+P Q   YM  +
Sbjct:   90 FVRKFILDYFFEERENLRFDL--YDVDSKSPNLSKHDFLGQVFCTLGEIVGSQGSRLE--------KPIVGIPGRKCGTIILTAEELNCCRDAVLMQFCANKLDKKDFFGKSDPFLVFYRSNEDGSFTICHKTEVVKNTLNPVWQAFKISVRALCNGDYDRTIKVEVYDWDRD---------GSHDFIGEFTTSYRELARGQS-QFNVYEVVNPKKKGKKKKYTNSGTVTLLSFLVETEVSFLDYIKGGTQINFTVAIDFTASNGNPAQPTSLHYMNPYQLNAYGMALKAVGEIVQDYDSDKMFPALGFGAKLPPDGRISHEFALNGNPQNPYCDGIEGVMEAYYRSLKSVQLYGPTNFAPVINHVARYASSVKDGSQYFVLLIVTDGVISDMAQTKESIVNASKLPMSIIIVGVGPAEFDAMVELDGDDVRVSSRGKYAERDIVQFVPFRDYI----DRSGNHILSMARLAKDVLAEIPEQFLSYMRAR 555          
BLAST of Copine-3 vs. UniProt/SwissProt
Match: sp|Q8JZW4|CPNE5_MOUSE (Copine-5 OS=Mus musculus OX=10090 GN=Cpne5 PE=1 SV=1)

HSP 1 Score: 316.62 bits (810), Expect = 1.504e-97
Identity = 193/497 (38.83%), Postives = 284/497 (57.14%), Query Frame = 1
Query:  358 FDAKLCIEYLFEEKQMIIIEIFEYDITQ---DGDNLLGEVDCSIGRVIHSGGVVL-KPLEI-TDEFKTTLGPLSPEVG-------------IYVEEDLTAKENIELKIRGIGLAKTEIFGKTDPYLMIFRCNNRSRYVQCYRTEVLKNTQNPDWSPIVVSYERLCNNDLNSVLCLRVYCGDGTLKESEEVDIACDQLVGEIKVTARELIQMRRMEEKQFELINPXXXXXXXSYLNSGIISVRAQKTNSEPTFLDFMFQGLELNFIVAIDLTLSNGDSSLPSSLHFMDCSLTNEYSVAIQAVLEILQEYDNDELFPAFGFGARVPPDYKICHEYPLNGDFENPYCRGAEGVIHAYQQTLKEVKLAGPTCFSPVIRHISRLAKASESGKHYFVLLILTDGSVDDWVETKKAVVETSYLPXXXXXXXXXXXKFSDMETLDQDFGLLMVSNEKACRDNVQFVKMRRYLRVAADGSDNIRWSKVALAKDVLAELPYQVNEYM 1794
            F  K  ++Y FEEKQ +  ++++ D         + LG+  C++G ++ S G  L KPL I T    +  G   P V              +  EE    ++   ++     L K + FGK+DP+L+ +R N    +  C++TEV+KNT NP W    +    LCN D +  + + VY  D                +GE   + REL + +  +   +E+INPKKK KKK Y+NSG +++ +    SE TFLD++  G ++NF VAID T SNG+ S  +SLH+M     N Y++A+ AV EI+Q YD+D++FPA GFGA++PPD ++ HE+PLNG+ ENP C G +G++ AY  +L+ V+L GPT F+PV+ H++R A A + G  Y VLLI+TDG + D  +TK+A+V  + LP+SII+VGVG  +F  M  LD D   +    + A RD VQFV  R Y+    D + N   S   LA+DVLAE+P Q+  YM
Sbjct:   76 FVRKFIVDYFFEEKQNLRFDLYDVDSKSPDLSKHDFLGQAFCTLGEIVGSSGSRLEKPLTIGTFSLNSRTGKPMPAVSNGGVPGKKCGTIILSAEELSNCRDVATMQFCANKLDKKDFFGKSDPFLVFYRSNEDGTFTICHKTEVMKNTLNPVWQTFSIPVRALCNGDYDRTIKVEVYDWDRD---------GSHDFIGEFTTSYRELARGQS-QFNIYEVINPKKKMKKKKYVNSGTVTLLSFAVESESTFLDYIKGGTQINFTVAIDFTASNGNPSQSTSLHYMSPYQLNAYALALTAVGEIIQHYDSDKMFPALGFGAKLPPDGRVSHEFPLNGNQENPSCCGIDGILEAYHSSLRTVQLYGPTNFAPVVTHVARNAAAVQDGSQYSVLLIITDGVISDMAQTKEAIVNAAKLPMSIIIVGVGQAEFDAMVELDGDDVRISSRGKLAERDIVQFVPFRDYV----DRTGNHVLSMARLARDVLAEIPDQLVSYM 558          
BLAST of Copine-3 vs. UniProt/SwissProt
Match: sp|Q9HCH3|CPNE5_HUMAN (Copine-5 OS=Homo sapiens OX=9606 GN=CPNE5 PE=1 SV=2)

HSP 1 Score: 313.153 bits (801), Expect = 3.040e-96
Identity = 191/497 (38.43%), Postives = 284/497 (57.14%), Query Frame = 1
Query:  358 FDAKLCIEYLFEEKQMIIIEIFEYDITQ---DGDNLLGEVDCSIGRVIHSGGVVL-KPLEITD-EFKTTLGPLSPEVG-------------IYVEEDLTAKENIELKIRGIGLAKTEIFGKTDPYLMIFRCNNRSRYVQCYRTEVLKNTQNPDWSPIVVSYERLCNNDLNSVLCLRVYCGDGTLKESEEVDIACDQLVGEIKVTARELIQMRRMEEKQFELINPXXXXXXXSYLNSGIISVRAQKTNSEPTFLDFMFQGLELNFIVAIDLTLSNGDSSLPSSLHFMDCSLTNEYSVAIQAVLEILQEYDNDELFPAFGFGARVPPDYKICHEYPLNGDFENPYCRGAEGVIHAYQQTLKEVKLAGPTCFSPVIRHISRLAKASESGKHYFVLLILTDGSVDDWVETKKAVVETSYLPXXXXXXXXXXXKFSDMETLDQDFGLLMVSNEKACRDNVQFVKMRRYLRVAADGSDNIRWSKVALAKDVLAELPYQVNEYM 1794
            F  K  ++Y FEEKQ +  ++++ D         + LG+  C++G ++ S G  L KPL I      +  G   P V              +  EE    ++   ++     L K + FGK+DP+L+ +R N    +  C++TEV+KNT NP W    +    LCN D +  + + VY  D                +GE   + REL + +  +   +E++NPKKK KKK Y+NSG +++ +    SE TFLD++  G ++NF VAID T SNG+ S  +SLH+M     N Y++A+ AV EI+Q YD+D++FPA GFGA++PPD ++ HE+PLNG+ ENP C G +G++ AY ++L+ V+L GPT F+PV+ H++R A A + G  Y VLLI+TDG + D  +TK+A+V  + LP+SII+VGVG  +F  M  LD D   +    + A RD VQFV  R Y+    D + N   S   LA+DVLAE+P Q+  YM
Sbjct:   76 FVRKFIVDYFFEEKQNLRFDLYDVDSKSPDLSKHDFLGQAFCTLGEIVGSPGSRLEKPLTIGAFSLNSRTGKPMPAVSNGGVPGKKCGTIILSAEELSNCRDVATMQFCANKLDKKDFFGKSDPFLVFYRSNEDGTFTICHKTEVMKNTLNPVWQTFSIPVRALCNGDYDRTIKVEVYDWDRD---------GSHDFIGEFTTSYRELARGQS-QFNIYEVVNPKKKMKKKKYVNSGTVTLLSFAVESECTFLDYIKGGTQINFTVAIDFTASNGNPSQSTSLHYMSPYQLNAYALALTAVGEIIQHYDSDKMFPALGFGAKLPPDGRVSHEFPLNGNQENPSCCGIDGILEAYHRSLRTVQLYGPTNFAPVVTHVARNAAAVQDGSQYSVLLIITDGVISDMAQTKEAIVNAAKLPMSIIIVGVGQAEFDAMVELDGDDVRISSRGKLAERDIVQFVPFRDYV----DRTGNHVLSMARLARDVLAEIPDQLVSYM 558          
BLAST of Copine-3 vs. UniProt/SwissProt
Match: sp|Q1RLL3|CPNE9_MOUSE (Copine-9 OS=Mus musculus OX=10090 GN=Cpne9 PE=1 SV=1)

HSP 1 Score: 311.227 bits (796), Expect = 4.618e-96
Identity = 191/487 (39.22%), Postives = 283/487 (58.11%), Query Frame = 1
Query:  358 FDAKLCIEYLFEEKQMIIIEIFEYD----ITQDGDNLLGEVDCSIGRVIHS-GGVVLKPLEITDEFKTTLGPLSPEVGIYVEEDLTAKENIELKIRGIGLAKTEIFGKTDPYLMIFRCNNRSRYVQCYRTEVLKNTQNPDWSPIVVSYERLCNNDLNSVLCLRVYCGDGTLKESEEVDIACDQLVGEIKVTARELIQMRRMEEKQFELINPXXXXXXXSYLNSGIISVRAQKTNSEPTFLDFMFQGLELNFIVAIDLTLSNGDSSLPSSLHFMDCSLTNEYSVAIQAVLEILQEYDNDELFPAFGFGARVPPDYKICHEYPLNGDFENPYCRGAEGVIHAYQQTLKEVKLAGPTCFSPVIRHISRLAKASESGKHYFVLLILTDGSVDDWVETKKAVVETSYLPXXXXXXXXXXXKFSDMETLDQDFGLLMVSNEKACRDNVQFVKMRRYLRVAADGSDNIRWSKVALAKDVLAELPYQVNEYMHRK 1803
            F  K  ++Y FEEKQ +  +++  D    I++  D  LG+   ++G VI   G  V +PL          G     + +  EE    ++   +++    L K + FGK+DP+L+ +R N    +  C++TEV+KNT NP W P  +    LCN D +  + + VY  D                +GE   + REL + +  +   +E++NP+KK KKK Y NSG +++ +   +SE TF+D++  G +LNF VAID T SNG+   P+SLH+M     + Y++A++AV EI+Q+YD+D+LFPA+GFGA++PP+ +I H++PLN + E+P C G EGV+ +Y Q+L+ V+L GPT F+PVI  ++R A     G  Y+VLLI+TDG + D  +TK+A+V  S LP+SII+VGVG   F  ME LD D   +      A RD VQFV  R Y+    D S N   S   LAKDVLAE+P Q+  YM  +
Sbjct:   67 FVRKFVLDYFFEEKQNLRFDVYNVDSKANISKPKD-FLGQAFLALGEVIGGQGSRVERPL------TGVPGKKCGTILLTAEELSNCRDIATMQLCANKLDKKDFFGKSDPFLVFYRSNEDGTFTICHKTEVVKNTLNPVWQPFSIPVRALCNGDYDRTVKIDVYDWDRD---------GSHDFIGEFTTSYRELSKAQN-QFTVYEVLNPRKKCKKKKYTNSGTVTLLSFSVDSEFTFVDYIKGGTQLNFTVAIDFTASNGNPLQPTSLHYMSPYQLSAYAMALKAVGEIIQDYDSDKLFPAYGFGAKLPPEGRISHQFPLNNNDEDPNCAGIEGVLESYFQSLRTVQLYGPTYFAPVINQVARAAAKISDGSQYYVLLIITDGVISDMTQTKEAIVSASSLPMSIIIVGVGPAMFEAMEELDGDDVRVSSRGRYAERDIVQFVPFRDYV----DRSGNQVLSMARLAKDVLAEIPEQLLSYMRTR 532          
BLAST of Copine-3 vs. TrEMBL
Match: A0A267G9Y0 (Uncharacterized protein (Fragment) OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig017750g6 PE=4 SV=1)

HSP 1 Score: 498.049 bits (1281), Expect = 2.120e-165
Identity = 267/535 (49.91%), Postives = 359/535 (67.10%), Query Frame = 1
Query:  271 WANISVETGGYIHSRDTIKTER-KSGHDITFDAKLCIEYLFEEKQMIIIEIF----EYDITQDGDNLLGEVDCSIGRVIHSGGVVLKPLEITDEFKTTLGPLSPEV-GIYVEEDLTAKENIELKIRGIGLAKTEIFGKTDPYLMIFRCNNRSRYVQCYRTEVLKNTQNPDWSPIVVSYERLCNNDLNSVLCLRVYCGDGTLKESEEVDIACDQLVGEIKVTARELIQMRRMEEKQFELINPXXXXXXXSYLNSGIISVRAQKTNSEPTFLDFMFQGLELNFIVAIDLTLSNGDSSLPSSLHFMDCSLTNEYSVAIQAVLEILQEYDNDELFPAFGFGARVPPDYKICHEYPLNGDFENPYCRGAEGVIHAYQQTLKEVKLAGPTCFSPVIRHISRLAKASESGKHYFVLLILTDGSVDDWVETKKAVVETSYLPXXXXXXXXXXXKFSDMETLDQDFGLLMVSNEKACRDNVQFVKMRRYLRVAADGSDNIRWSKVALAKDVLAELPYQVNEYMHRKTKLTNYLENLPTQRSTAV 1857
            +A I++ +G Y+  +DT+ TE     H+ T+   L   Y FEE+QMI +EI     ++        ++G    S+G +IHSGG               L   SP V  I+VEE    KEN+ LK+ G GL K ++FGK+DPY++I + N++ R V+ YRTEV+KNT +PDW PI VS +RLC  DL   +  R Y  DG   + E+ DI  D+ +GE   T +EL       E  FELINP+K KKKK+Y NSG ++ +    +++ +FLD+MF G +L F VAID+T SNG  S P+SLH+ D    N+Y++A+QAVLEI+Q+YD+D+L PAFGFG R PPDY++ HE+PLNGD  NP+C+GA GV+ AY+  L+EV+L+GPT F+PVI+H+SRLA   + G  Y+VLLILTDG++DDW E K+AV+E SYLPVSIIVVG+G G F++ME LDQD  LL    +KACRD VQFV++R+YLRVAADGSD +RWSKVALAKDVL ELP Q+ EYM R+    N L+   +  S+A 
Sbjct:   50 FAVIALHSGSYMTEKDTVTTETVDKTHNPTYSIPLITSYKFEERQMIELEIHCAMDDHSSRAASRKVIGSCTVSLGHLIHSGG----------SLDCQLCSSSPAVCTIHVEEYAGNKENMLLKLNGRGLDKKDLFGKSDPYMIIDKRNDKGRLVRAYRTEVIKNTLDPDWKPIKVSVDRLCGGDLRREIRFRCYDWDGAEGDHEDKDIEFDEFIGEFATTPKELFS-NDGREVTFELINPRKAKKKKNYRNSGTVTAKTIPIDADFSFLDYMFSGTDLCFTVAIDMTASNGSPSQPTSLHYTDPFTPNQYTIAMQAVLEIIQDYDSDQLLPAFGFGCRAPPDYRVSHEWPLNGDSANPFCQGAAGVLEAYRHCLEEVRLSGPTHFAPVIKHVSRLALNHQDGSRYYVLLILTDGTIDDWTECKRAVIEASYLPVSIIVVGIGSGNFTEMELLDQDVWLLEEGGQKACRDIVQFVELRKYLRVAADGSDGVRWSKVALAKDVLQELPSQILEYMRRRRLKPNRLQQPQSPSSSAA 573          
BLAST of Copine-3 vs. TrEMBL
Match: A0A267FGY6 (Uncharacterized protein (Fragment) OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig017750g2 PE=4 SV=1)

HSP 1 Score: 494.967 bits (1273), Expect = 3.381e-164
Identity = 265/535 (49.53%), Postives = 358/535 (66.92%), Query Frame = 1
Query:  271 WANISVETGGYIHSRDTIKTER-KSGHDITFDAKLCIEYLFEEKQMIIIEIF----EYDITQDGDNLLGEVDCSIGRVIHSGGVVLKPLEITDEFKTTLGPLSPEV-GIYVEEDLTAKENIELKIRGIGLAKTEIFGKTDPYLMIFRCNNRSRYVQCYRTEVLKNTQNPDWSPIVVSYERLCNNDLNSVLCLRVYCGDGTLKESEEVDIACDQLVGEIKVTARELIQMRRMEEKQFELINPXXXXXXXSYLNSGIISVRAQKTNSEPTFLDFMFQGLELNFIVAIDLTLSNGDSSLPSSLHFMDCSLTNEYSVAIQAVLEILQEYDNDELFPAFGFGARVPPDYKICHEYPLNGDFENPYCRGAEGVIHAYQQTLKEVKLAGPTCFSPVIRHISRLAKASESGKHYFVLLILTDGSVDDWVETKKAVVETSYLPXXXXXXXXXXXKFSDMETLDQDFGLLMVSNEKACRDNVQFVKMRRYLRVAADGSDNIRWSKVALAKDVLAELPYQVNEYMHRKTKLTNYLENLPTQRSTAV 1857
            +A I++ +G Y+  +DT+ TE     H+ T+   L   Y FEE+QMI +EI     ++        ++G    S+G +IHSGG               L   SP V  I+VEE    KEN+ LK+ G GL K ++FGK+DPY++I + N++ R V+ YRTEV+KNT +PDW PI VS +RLC  +    +  R Y  DG   + E+ DI  D+ +GE   T +EL       E  FELINP+K KKKK+Y NSG ++ +    +++ +FLD+MF G +L F VAID+T SNG  S P+SLH+ D    N+Y++A+QAVLEI+Q+YD+D+L PAFGFG R PPDY++ HE+PLNGD  NP+C+GA GV+ AY+  L+EV+L+GPT F+PVI+H+SRLA   + G  Y+VLLILTDG++DDW E K+AV+E SYLPVSIIVVG+G G F++ME LDQD  LL    +KACRD VQFV++R+YLRVAADGSD +RWSKVALAKDVL ELP Q+ EYM R+    N L+   +  S+A 
Sbjct:   50 FAVIALHSGSYMTEKDTVTTETVDKTHNPTYSIPLITSYKFEERQMIELEIHCAMDDHSSRAASRKVIGSCTVSLGHLIHSGG----------SLDCQLCSSSPAVCTIHVEEYAGNKENMLLKLNGRGLDKKDLFGKSDPYMIIDKRNDKGRLVRAYRTEVIKNTLDPDWKPIKVSVDRLCGGEFRREIRFRCYDWDGAEGDHEDKDIEFDEFIGEFATTPKELFS-NDGREVTFELINPRKAKKKKNYRNSGTVTAKTIPIDADFSFLDYMFSGTDLCFTVAIDMTASNGSPSQPTSLHYTDPFTPNQYTIAMQAVLEIIQDYDSDQLLPAFGFGCRAPPDYRVSHEWPLNGDSANPFCQGAAGVLEAYRHCLEEVRLSGPTHFAPVIKHVSRLALNHQDGSRYYVLLILTDGTIDDWTECKRAVIEASYLPVSIIVVGIGSGNFTEMELLDQDVWLLEEGGQKACRDIVQFVELRKYLRVAADGSDGVRWSKVALAKDVLQELPSQILEYMRRRRLKPNRLQQPQSPSSSAA 573          
BLAST of Copine-3 vs. TrEMBL
Match: A0A4S2L3S0 (C2 domain-containing protein OS=Opisthorchis felineus OX=147828 GN=CRM22_009940 PE=4 SV=1)

HSP 1 Score: 494.582 bits (1272), Expect = 3.847e-162
Identity = 266/539 (49.35%), Postives = 371/539 (68.83%), Query Frame = 1
Query:  199 LNGKPKVLISLIVNNLSGTEGKLYWANISVETGGYIHSRDTIKTE-RKSGHDITFDAKLCIEYLFEEKQMIIIEIFEYDITQDGDN-LLGEVDCSIGRVIHSGGVVLKPLEITDEFKTTLGP-LSPEVGIYVEEDLTAKENIELKIRGIGLAKTEIFGKTDPYLMIFRCNNRSRYVQCYRTEVLKNTQNPDWSPIVVSYERLCNNDLNSVLCLRVYCGDGTLKESEEVDIACDQLVGEIKVTARELIQMRRMEEK--QFELINPXXXXXXXSYLNSGIISVRAQKTNSEPTFLDFMFQGLELNFIVAIDLTLSNGDSSLPSSLHFMDCSLTNEYSVAIQAVLEILQEYDNDELFPAFGFGARVPPDYKICHEYPLNGDFENPYCRGAEGVIHAYQQTLKEVKLAGPTCFSPVIRHISRLAKASESGKHYFVLLILTDGSVDDWVETKKAVVETSYLPXXXXXXXXXXXKFSDMETLDQDFGLLMVSNEKACRDNVQFVKMRRYLRVAADGSDNIRWSKVALAKDVLAELPYQVNEYMHR 1800
            +  +P++ I +   NL  T+    +A  SV  GG +H +   +TE ++   +  F  +L +EY FEE+Q+I  EIF+ +     D+ LLG   C++GRVIHSGG +  PL   DE K  L P   P V + + ED  +KENI LK++G  L K + FGK+DPY+ I+R N R +  + YR+EV+KNT  PD+ PI+V  +RLC  +++  LC R +  DG L +SEEVD   D L+GE   T  EL+   R +E   +F+LINP KKK+KK+Y +SG + VR     S  +FLD++F G  +N ++ +DL+       +P+S         NEYSVAIQAV+EILQEYD+D+LFPA+GFG+R+    KICH+YPL+GD  N +C+G  GV+ AY+++ + + L+GP CFSP+IR +S  A+ ++  ++Y+VLLILT+G+VDDW+ETKKAV+ETS+LP+SIIV+G+GGGKF+DME LDQDFGLL V  E+ACRDNVQFV+MRR+LR+AADGSDN+RWSKV LAK+VLAELP Q+ +Y  R
Sbjct:    1 MPSRPRIQIGISCTNLP-TKLPGSYAKFSVAHGGTLHEKHVTETEIQRQTRNPIFLTRLNLEYFFEERQIITSEIFQCEREDREDSQLLGFGQCTVGRVIHSGGELELPLICNDEQKNLLDPGRPPSVFVCIREDPFSKENIYLKMQGFNLDKKDFFGKSDPYVTIYRRNERGKLQKAYRSEVIKNTLFPDFRPILVCLDRLCGGNVDCELCFRCFDWDGALGDSEEVDTELDDLIGEFTTTISELL---RSDESGLEFKLINPPKKKRKKNYQDSGQLKVRLSLAQSNFSFLDYIFGGTSINVVIGVDLSNHISSKQMPASRQIEVAQSCNEYSVAIQAVMEILQEYDSDQLFPAYGFGSRLSSGGKICHKYPLSGDENNYFCKGMAGVLEAYRRSFEALHLSGPICFSPIIRDVSDTARRNKDTENYYVLLILTNGTVDDWIETKKAVIETSFLPISIIVIGIGGGKFADMEILDQDFGLLKVGQEQACRDNVQFVQMRRFLRLAADGSDNLRWSKVGLAKEVLAELPSQILDYFER 535          
BLAST of Copine-3 vs. TrEMBL
Match: A0A267ER93 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig028292g1 PE=4 SV=1)

HSP 1 Score: 477.248 bits (1227), Expect = 1.550e-157
Identity = 256/533 (48.03%), Postives = 366/533 (68.67%), Query Frame = 1
Query:  214 KVLISLIVNNLSGTEGKLYWANISVETGGYIHSRDTIKTER-KSGHDITFDAKLCIEYLFEEKQMIIIEIF--EYDITQDGDNLLGEVDCSIGRVIHSGGVVLKPLEITDEFKTTLGPLSPEVGIYVEEDLTAKENIELKIRGIGLAKTEIFGKTDPYLMIFRCNNRSRYVQCYRTEVLKNTQNPDWSPIVVSYERLCNNDLNSVLCLRVYCGDGTLKESEEVDIACDQLVGEIKVTARELIQMRRMEEKQFELINPXXXXXXXSYLNSGIISVRAQKTNSEPTFLDFMFQGLELNFIVAIDLTLSNGDSSLPSSLHFMDCSLTNEYSVAIQAVLEILQEYDNDELFPAFGFGARVPPDYKICHEYPLNGDFENPYCRGAEGVIHAYQQTLKEVKLAGPTCFSPVIRHISRLAKASESGKHYFVLLILTDGSVDDWVETKKAVVETSYLPXXXXXXXXXXXKFSDMETLDQDFGLLMVSNEKACRDNVQFVKMRRYLRVAADGSDNIRWSKVALAKDVLAELPYQVNEYMHRK 1803
            KV+IS+   +L   +    +A IS+ +G Y++ +DT+ TE  +      F   L   Y FEE+QM+ +E++  + ++      ++G    S+G VIH+GG ++  L+         G    +   +VEE    KE + LK+ G GL K ++FGK+DPY++I + N++ R V+ YRTEV+KNT +PDW P+ VS ++LC  D    +  R +  DG   + E+ DI  D+L+GE   T  +L+  R   E  F+L+NP+K+KKKK+Y NSG+I+++    +S+ +FLD+MF G +L F VAID+T SNG+ S P+SLH+ D    N+Y++A+QAVLEI+Q+YD+D+L PAFGFG RVPPDY++ HE+PLNGD  NP+C GA GV+ AY+Q L EV+ +GPT F+PVIRH+SRLA   + G  Y+VLLILTDG++DDW + K+AV+E SYLPVSIIV+G+G G F++ME LDQD  LL    +KACRD VQFV++R+YLR AADG++++RWSKVALAKDVL ELP Q+ EYM R+
Sbjct:   16 KVVISVKCRDLPVEKS---FAVISLHSGSYMNEKDTVTTETVERSSSPAFRTPLLAVYKFEERQMVELEVYSAQEEVRHGERRVIGTCSVSLGHVIHNGGQIVAQLDSGAGSGANSG--RAKCLFHVEEYGGNKETLMLKLSGRGLDKKDLFGKSDPYVIIEKRNDKGRLVRAYRTEVIKNTLDPDWKPVKVSMDKLCGGDFGREIRFRCFDWDGAEGDPEDKDIEFDELIGEFFTTPSDLLDGR---EICFDLVNPRKQKKKKNYKNSGVINLKVISVDSQGSFLDYMFGGTDLCFTVAIDMTASNGNPSQPTSLHYTDPFTPNQYTIAMQAVLEIVQDYDSDQLLPAFGFGCRVPPDYRVSHEWPLNGDSNNPFCHGAGGVMEAYRQCLDEVRPSGPTHFAPVIRHVSRLAVGHQDGSRYYVLLILTDGTIDDWTDCKRAVIEASYLPVSIIVIGIGNGNFTEMELLDQDVWLLEEGGQKACRDIVQFVELRKYLRQAADGTESVRWSKVALAKDVLQELPSQIMEYMRRR 540          
BLAST of Copine-3 vs. TrEMBL
Match: A0A267EIM6 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig028292g2 PE=4 SV=1)

HSP 1 Score: 476.478 bits (1225), Expect = 2.839e-157
Identity = 256/533 (48.03%), Postives = 366/533 (68.67%), Query Frame = 1
Query:  214 KVLISLIVNNLSGTEGKLYWANISVETGGYIHSRDTIKTER-KSGHDITFDAKLCIEYLFEEKQMIIIEIF--EYDITQDGDNLLGEVDCSIGRVIHSGGVVLKPLEITDEFKTTLGPLSPEVGIYVEEDLTAKENIELKIRGIGLAKTEIFGKTDPYLMIFRCNNRSRYVQCYRTEVLKNTQNPDWSPIVVSYERLCNNDLNSVLCLRVYCGDGTLKESEEVDIACDQLVGEIKVTARELIQMRRMEEKQFELINPXXXXXXXSYLNSGIISVRAQKTNSEPTFLDFMFQGLELNFIVAIDLTLSNGDSSLPSSLHFMDCSLTNEYSVAIQAVLEILQEYDNDELFPAFGFGARVPPDYKICHEYPLNGDFENPYCRGAEGVIHAYQQTLKEVKLAGPTCFSPVIRHISRLAKASESGKHYFVLLILTDGSVDDWVETKKAVVETSYLPXXXXXXXXXXXKFSDMETLDQDFGLLMVSNEKACRDNVQFVKMRRYLRVAADGSDNIRWSKVALAKDVLAELPYQVNEYMHRK 1803
            KV+IS+   +L   +    +A IS+ +G Y++ +DT+ TE  +      F   L   Y FEE+QM+ +E++  + ++      ++G    S+G VIH+GG ++  L+         G    +   +VEE    KE + LK+ G GL K ++FGK+DPY++I + N++ R V+ YRTEV+KNT +PDW P+ VS ++LC  D    +  R +  DG   + E+ DI  D+L+GE   T  +L+  R   E  F+L+NP+K+KKKK+Y NSG+I+++    +S+ +FLD+MF G +L F VAID+T SNG+ S P+SLH+ D    N+Y++A+QAVLEI+Q+YD+D+L PAFGFG RVPPDY++ HE+PLNGD  NP+C GA GV+ AY+Q L EV+ +GPT F+PVIRH+SRLA   + G  Y+VLLILTDG++DDW + K+AV+E SYLPVSIIV+G+G G F++ME LDQD  LL    +KACRD VQFV++R+YLR AADG++++RWSKVALAKDVL ELP Q+ EYM R+
Sbjct:   16 KVVISVKCRDLPVEKS---FAVISLHSGSYMNEKDTVTTETVERSSSPAFRTPLLAVYKFEERQMVELEVYSAQEEVRHGERRVIGTCSVSLGHVIHNGGQIVAQLDSGVGSGANSG--RAKCLFHVEEYGGNKETLMLKLSGRGLDKKDLFGKSDPYVIIEKRNDKGRLVRAYRTEVIKNTLDPDWKPVKVSMDKLCGGDFGREIRFRCFDWDGAEGDPEDKDIEFDELIGEFFTTPSDLLDGR---EICFDLVNPRKQKKKKNYKNSGVINLKVISVDSQGSFLDYMFGGTDLCFTVAIDMTASNGNPSQPTSLHYTDPFTPNQYTIAMQAVLEIVQDYDSDQLLPAFGFGCRVPPDYRVSHEWPLNGDSNNPFCHGAGGVMEAYRQCLDEVRPSGPTHFAPVIRHVSRLAVGHQDGSRYYVLLILTDGTIDDWTDCKRAVIEASYLPVSIIVIGIGNGNFTEMELLDQDVWLLEEGGQKACRDIVQFVELRKYLRQAADGTESVRWSKVALAKDVLQELPSQIMEYMRRR 540          
BLAST of Copine-3 vs. Ensembl Cavefish
Match: cpne5b (copine-5 [Source:NCBI gene;Acc:103046149])

HSP 1 Score: 327.791 bits (839), Expect = 4.101e-103
Identity = 192/486 (39.51%), Postives = 287/486 (59.05%), Query Frame = 1
Query:  358 FDAKLCIEYLFEEKQMIIIEIFEYDITQ---DGDNLLGEVDCSIGRVIHSGGVVL-KPLEITDEFKTTLGPLSPEVGIYVEEDLTAKENIELKIRGIGLAKTEIFGKTDPYLMIFRCNNRSRYVQCYRTEVLKNTQNPDWSPIVVSYERLCNNDLNSVLCLRVYCGDGTLKESEEVDIACDQLVGEIKVTARELIQMRRMEEKQFELINPXXXXXXXSYLNSGIISVRAQKTNSEPTFLDFMFQGLELNFIVAIDLTLSNGDSSLPSSLHFMDCSLTNEYSVAIQAVLEILQEYDNDELFPAFGFGARVPPDYKICHEYPLNGDFENPYCRGAEGVIHAYQQTLKEVKLAGPTCFSPVIRHISRLAKASESGKHYFVLLILTDGSVDDWVETKKAVVETSYLPXXXXXXXXXXXKFSDMETLDQDFGLLMVSNEKACRDNVQFVKMRRYLRVAADGSDNIRWSKVALAKDVLAELPYQVNEYMHRK 1803
            F  K  ++Y FEEKQ +  ++++ D         + LG++ C++G ++ S    L KPL          G     + +  EE    +++  ++     L K + FGK+DP+++ +R N    +  C++TEV+KNT NP W    +    LCN D +  + + VY  D                +GE   + REL + +  +   +E++NPKKK KKK Y+NSG +++ +    SE TFLD++  G ++NF VAID T SNG+ S  +SLH+M+    N Y++A++AV EI+Q+YD+D++FPA GFGA++PPD ++ HE+PLNG+ ENPYC G EG++ AY Q+LK V+L GPT F+PV+ H++R A A + G  YFVLLI+TDG + D  +TK+A+V  + LP+SII+VGVG  +F  M  LD D   +    + A RD VQFV  R Y+    D + N   S   LAKDVLAE+P Q   YM  +
Sbjct:   81 FVRKFILDYFFEEKQNLRFDLYDVDSKSPDLSKHDFLGQMFCTLGEIVGSPASRLDKPL------GGIPGKKCGTIILSAEELGNCRDSATMQFCANKLDKKDFFGKSDPFMVFYRSNEDGTFTICHKTEVVKNTLNPVWQSFTIPVRALCNGDFDRTIKVEVYDWDRD---------GSHDFIGEFTTSYRELARGQS-QFNVYEVVNPKKKMKKKKYVNSGTVTLLSFSVESEFTFLDYIKGGTQINFTVAIDFTASNGNPSQSTSLHYMNPYQMNAYAMALKAVGEIIQDYDSDKMFPALGFGAKLPPDGRVSHEFPLNGNIENPYCNGIEGILEAYHQSLKTVQLYGPTNFAPVVNHVARYAAAVQDGSQYFVLLIITDGVISDMSQTKEAIVNGAKLPMSIIIVGVGQAEFDAMVELDGDDIRISSRGKLAERDIVQFVPFRDYM----DRTGNHVLSMARLAKDVLAEIPDQFISYMKSR 546          
BLAST of Copine-3 vs. Ensembl Cavefish
Match: cpne5b (copine-5 [Source:NCBI gene;Acc:103046149])

HSP 1 Score: 327.02 bits (837), Expect = 9.791e-103
Identity = 192/491 (39.10%), Postives = 289/491 (58.86%), Query Frame = 1
Query:  358 FDAKLCIEYLFEEKQMIIIEIFEYDITQ--------DGDNLLGEVDCSIGRVIHSGGVVL-KPLEITDEFKTTLGPLSPEVGIYVEEDLTAKENIELKIRGIGLAKTEIFGKTDPYLMIFRCNNRSRYVQCYRTEVLKNTQNPDWSPIVVSYERLCNNDLNSVLCLRVYCGDGTLKESEEVDIACDQLVGEIKVTARELIQMRRMEEKQFELINPXXXXXXXSYLNSGIISVRAQKTNSEPTFLDFMFQGLELNFIVAIDLTLSNGDSSLPSSLHFMDCSLTNEYSVAIQAVLEILQEYDNDELFPAFGFGARVPPDYKICHEYPLNGDFENPYCRGAEGVIHAYQQTLKEVKLAGPTCFSPVIRHISRLAKASESGKHYFVLLILTDGSVDDWVETKKAVVETSYLPXXXXXXXXXXXKFSDMETLDQDFGLLMVSNEKACRDNVQFVKMRRYLRVAADGSDNIRWSKVALAKDVLAELPYQVNEYMHRK 1803
            F  K  ++Y FEEKQ +  ++++ D           + ++ LG++ C++G ++ S    L KPL          G     + +  EE    +++  ++     L K + FGK+DP+++ +R N    +  C++TEV+KNT NP W    +    LCN D +  + + VY  D                +GE   + REL + +  +   +E++NPKKK KKK Y+NSG +++ +    SE TFLD++  G ++NF VAID T SNG+ S  +SLH+M+    N Y++A++AV EI+Q+YD+D++FPA GFGA++PPD ++ HE+PLNG+ ENPYC G EG++ AY Q+LK V+L GPT F+PV+ H++R A A + G  YFVLLI+TDG + D  +TK+A+V  + LP+SII+VGVG  +F  M  LD D   +    + A RD VQFV  R Y+    D + N   S   LAKDVLAE+P Q   YM  +
Sbjct:   81 FVRKFILDYFFEEKQNLRFDLYDVDSKSPDLSKHPSECNDFLGQMFCTLGEIVGSPASRLDKPL------GGIPGKKCGTIILSAEELGNCRDSATMQFCANKLDKKDFFGKSDPFMVFYRSNEDGTFTICHKTEVVKNTLNPVWQSFTIPVRALCNGDFDRTIKVEVYDWDRD---------GSHDFIGEFTTSYRELARGQS-QFNVYEVVNPKKKMKKKKYVNSGTVTLLSFSVESEFTFLDYIKGGTQINFTVAIDFTASNGNPSQSTSLHYMNPYQMNAYAMALKAVGEIIQDYDSDKMFPALGFGAKLPPDGRVSHEFPLNGNIENPYCNGIEGILEAYHQSLKTVQLYGPTNFAPVVNHVARYAAAVQDGSQYFVLLIITDGVISDMSQTKEAIVNGAKLPMSIIIVGVGQAEFDAMVELDGDDIRISSRGKLAERDIVQFVPFRDYM----DRTGNHVLSMARLAKDVLAEIPDQFISYMKSR 551          
BLAST of Copine-3 vs. Ensembl Cavefish
Match: CPNE8 (copine 8 [Source:HGNC Symbol;Acc:HGNC:23498])

HSP 1 Score: 321.242 bits (822), Expect = 9.539e-101
Identity = 195/488 (39.96%), Postives = 284/488 (58.20%), Query Frame = 1
Query:  358 FDAKLCIEYLFEEKQMIIIEIFEYDITQDGDNL-----LGEVDCSIGRVIHSGGVVL-KPLEITDEFKTTLGPLSPEVGIYVEEDLTAKENIELKIRGIGLAKTEIFGKTDPYLMIFRCNNRSRYVQCYRTEVLKNTQNPDWSPIVVSYERLCNNDLNSVLCLRVYCGDGTLKESEEVDIACDQLVGEIKVTARELIQMRRMEEKQFELINPXXXXXXXSYLNSGIISVRAQKTNSEPTFLDFMFQGLELNFIVAIDLTLSNGDSSLPSSLHFMDCSLTNEYSVAIQAVLEILQEYDNDELFPAFGFGARVPPDYKICHEYPLNGDFENPYCRGAEGVIHAYQQTLKEVKLAGPTCFSPVIRHISRLAKASESGKHYFVLLILTDGSVDDWVETKKAVVETSYLPXXXXXXXXXXXKFSDMETLDQDFGLLMVSNEKACRDNVQFVKMRRYLRVAADGSDNIRWSKVALAKDVLAELPYQVNEYMHRK 1803
            F  K  ++Y FEE+Q +  ++  YD+     NL     LG+  C++G ++ S G  L KPL          G     + +  EE    +E++ ++  G  L K + FGK+DP+L+ +R N    +  C++TEV+KNT NP W    +    LCN D +S                          +GE   + REL + +  +   +E+INPKKK KKK YLNSG +++ +   + + TFLD++  G ++NF VAID T SNG+ + P+SLH+M     N Y++A++AV EI+Q+YD+D++FPA GFGA++PPD ++ HE+ LNG+ +NPYC G +GV+ AY Q+LK V+L GPT FSPVI H++R A + + G  YFVLLI+TDG + D  +TK+++V  S LP+SII+VGVG  +F  M  LD D   +      A RD VQFV  R Y+    D + N   S   LAKDVLAE+P Q   YM  +
Sbjct:   83 FVRKFILDYFFEERQNLRFDL--YDVDSKSSNLSKHDFLGQAQCTLGEIVGSMGSRLEKPL------GGIPGKKCGTIIVKAEELNNCRESVMMQFCGNKLDKKDFFGKSDPFLVFYRSNEDGTFTICHKTEVVKNTLNPVWQAFKIPVRALCNGDYDS-----------------------HDFIGEFSTSYRELSRGQS-QFNVYEVINPKKKGKKKKYLNSGTVTLLSFLVDIDVTFLDYIKGGTQINFTVAIDFTASNGNPAQPTSLHYMSPYQLNAYAMALKAVGEIIQDYDSDKMFPALGFGAKLPPDGRVSHEFALNGNPQNPYCNGIDGVMEAYYQSLKSVQLYGPTNFSPVINHVARYAASVKDGSQYFVLLIITDGVISDMAQTKESIVNASCLPMSIIIVGVGPAEFDAMVELDGDEVRISSRGRYAERDIVQFVPFRDYI----DRTGNHILSMARLAKDVLAEIPDQFLSYMKTR 534          
BLAST of Copine-3 vs. Ensembl Cavefish
Match: cpne1 (copine-3-like [Source:NCBI gene;Acc:103034615])

HSP 1 Score: 315.079 bits (806), Expect = 1.393e-98
Identity = 189/501 (37.72%), Postives = 293/501 (58.48%), Query Frame = 1
Query:  325 KTER-KSGHDITFDAKLCIEYLFEEKQMIIIEIFEYD---ITQDGDNLLGEVDCSIGRVIHSGGVVLKPLEITDEFKTTLGPLSPEVGIYVEEDLTAKENIELKIRGIGLAKTEIFGKTDPYLMIFRCNNRSRYVQCYRTEVLKNTQNPDWSPIVVSYERLCNNDLNSVLCLRVYCGDGTLKESEEVDIACDQLVGEIKVTARELIQMRRMEEKQFELINPXXXXXXXSYLNSGIISVRAQKTNSEPTFLDFMFQGLELNFIVAIDLTLSNGDSSLPSSLHFMDCSLTNEYSVAIQAVLEILQEYDNDELFPAFGFGARVPPDYKICHEYPLNGDFENPYCRGAEGVIHAYQQTLKEVKLAGPTCFSPVIRHISRLAKAS---ESGKHYFVLLILTDGSVDDWVETKKAVVETSYLPXXXXXXXXXXXKFSDMETLDQDFGLLMV-SNEKACRDNVQFVKMRRYLRVAADGSDNIRWSKVALAKDVLAELPYQVNEYMHRK 1803
            +TER K+  D  F  +LC++Y FE+ Q + + +++ D   +    D+ LG  +C++G+++ +  V   PLE+        G ++      V +++     I L++    L K ++FGK+DP+L  F+  +   +   +RTEV+KN  NP W    VS    CN D N  L  +V+C D     S +       L+G  +    EL++       +F+ I+P+K+KKKKSY NSG++ ++  K  ++ TFLD++  G ++NF V ID T SNGD   P SLH++    TN+Y  AI +V +++++YD D+LFPAFGFGA+VPPD+K+ HE+ LN +  +P+C+G EG++ AY+  L +V+L GPT FSP+I H++R+A  +    +   YFVLLI+TDG + D  +TK+A+V +S LP+SII+VGVG   F  ME LD D G+L   S E   RD VQFV  + +     +          ALA+ VLAE+P Q+  Y   +
Sbjct:   47 RTERVKNCQDPEFSKRLCVDYHFEKVQKLKLGVYDIDNKSVDLKDDDYLGGFECTLGQIVSTKKVT-NPLELKKGKPAGKGTIT-----IVADEVKDNRAIVLEVEARNLDKKDMFGKSDPFLEFFKQADDGSWTLVHRTEVIKNNLNPSWKKFTVSVGTFCNADFNKPL--KVHCSDYDSDGSHD-------LIGIFQTNVVELLKADSGSGVEFDCIHPEKQKKKKSYKNSGVVRIKNCKIEAQYTFLDYVMGGCQINFTVGIDFTGSNGDPRSPESLHYLSPDGTNQYLNAIWSVGQVIKDYDTDKLFPAFGFGAQVPPDFKVSHEFALNFNPNSPFCQGIEGIVQAYRAALPQVRLYGPTNFSPIINHVARIAAGAAQQSNAAQYFVLLIITDGEITDLDQTKQAIVNSSKLPMSIIIVGVGEADFKAMEVLDGDNGVLKAPSGEPVSRDIVQFVPFKSFASAPRE----------ALAQTVLAEVPGQLVSYFKMR 522          
BLAST of Copine-3 vs. Ensembl Cavefish
Match: cpne1 (copine-3-like [Source:NCBI gene;Acc:103034615])

HSP 1 Score: 316.235 bits (809), Expect = 2.000e-98
Identity = 192/501 (38.32%), Postives = 297/501 (59.28%), Query Frame = 1
Query:  325 KTER-KSGHDITFDAKLCIEYLFEEKQMIIIEIFEYD---ITQDGDNLLGEVDCSIGRVIHSGGVVLKPLEITDEFKTTLGPLSPEVGIYVEEDLTAKENIELKIRGIGLAKTEIFGKTDPYLMIFRCNNRSRYVQCYRTEVLKNTQNPDWSPIVVSYERLCNNDLNSVLCLRVYCGDGTLKESEEVDIACDQLVGEIKVTARELIQMRRMEEKQFELINPXXXXXXXSYLNSGIISVRAQKTNSEPTFLDFMFQGLELNFIVAIDLTLSNGDSSLPSSLHFMDCSLTNEYSVAIQAVLEILQEYDNDELFPAFGFGARVPPDYKICHEYPLNGDFENPYCRGAEGVIHAYQQTLKEVKLAGPTCFSPVIRHISRLAKAS---ESGKHYFVLLILTDGSVDDWVETKKAVVETSYLPXXXXXXXXXXXKFSDMETLDQDFGLLMV-SNEKACRDNVQFVKMRRYLRVAADGSDNIRWSKVALAKDVLAELPYQVNEYMHRK 1803
            +TER K+  D  F  +LC++Y FE+ Q + + +++ D   +    D+ LG  +C++G+++ +  V   PLE+        G ++      V +++     I L++    L K ++FGK+DP+L  F+  +   +   +RTEV+KN  NP W    VS    CN D N  L  +V C D      ++ D + D L+GE   T   L++ R  +  +F+ I+P+K+KKKKSY NSG++ ++  K  ++ TFLD++  G ++NF V ID T SNGD   P SLH++    TN+Y  AI +V +++++YD D+LFPAFGFGA+VPPD+K+ HE+ LN +  +P+C+G EG++ AY+  L +V+L GPT FSP+I H++R+A  +    +   YFVLLI+TDG + D  +TK+A+V +S LP+SII+VGVG   F  ME LD D G+L   S E   RD VQFV  + +     +          ALA+ VLAE+P Q+  Y   +
Sbjct:  109 RTERVKNCQDPEFSKRLCVDYHFEKVQKLKLGVYDIDNKSVDLKDDDYLGGFECTLGQIVSTKKVT-NPLELKKGKPAGKGTIT-----IVADEVKDNRAIVLEVEARNLDKKDMFGKSDPFLEFFKQADDGSWTLVHRTEVIKNNLNPSWKKFTVSVGTFCNADFNKPL--KVACYD------KDEDTSSD-LIGEFSCTTANLLEARD-QGVEFDCIHPEKQKKKKSYKNSGVVRIKNCKIEAQYTFLDYVMGGCQINFTVGIDFTGSNGDPRSPESLHYLSPDGTNQYLNAIWSVGQVIKDYDTDKLFPAFGFGAQVPPDFKVSHEFALNFNPNSPFCQGIEGIVQAYRAALPQVRLYGPTNFSPIINHVARIAAGAAQQSNAAQYFVLLIITDGEITDLDQTKQAIVNSSKLPMSIIIVGVGEADFKAMEVLDGDNGVLKAPSGEPVSRDIVQFVPFKSFASAPRE----------ALAQTVLAEVPGQLVSYFKMR 583          
BLAST of Copine-3 vs. Ensembl Sea Lamprey
Match: cpne2 (copine II [Source:ZFIN;Acc:ZDB-GENE-030131-7896])

HSP 1 Score: 293.893 bits (751), Expect = 4.475e-91
Identity = 196/493 (39.76%), Postives = 286/493 (58.01%), Query Frame = 1
Query:  358 FDAKLCIEYLFEEKQMIIIEIFEYDITQD---GDNLLGEVDCSIGRVIHSGGVVLKPLEITDEFKTTLGPLSPEVGIYVEEDLTAKENIELKIRGIGLAKTEIFGKTDPYLMIFRCNNRSRYVQCYRTEVLKNTQNPDWSPIVVSYERLCNNDLNSVLCLRVYCGDGTLKESEEVDIACDQLVGEIKVTARELIQMR-RMEEKQFELINPXXXXXXXSYLNSGIISVRAQKTNSEPTFLDFMFQGLELNFIVAIDLTLSNGDSSLPSSLHFMDCSLTNEYSVAIQAVLEILQEYDNDELFPAFGFGARVPPDYKICHEYPLNGDFENPYCRGAEGVIHAYQQTLKEVKLAGPTCFSPVIRHISRL---AKASESGKHYFVLLILTDGSVDDWVETKKAVVETSYLPXXXXXXXXXXXKFSDMETLDQDFGLLMV-SNEKACRDNVQFVKMRRYLRVAADGSDNIRWSKVA---LAKDVLAELPYQVNEYMHRK 1803
            F  KL +EY FEE Q +   +F+ D         + LGE+  ++G+++ S   + +PL + D+     G ++        E++T    I L + G  L K ++FGK+DPYL I++ +    ++  +RTEV++NT +P W P  +  + LCN DL     +   C D     S +       L+GE       L +    ME  +FE IN KKK+KKKSY NSGII  ++ K + + TFLD++F G +L+F V ID T SNG+    SSLH++  +  N+Y  AI AV +I+Q+YD D+LFPA GFGA++PPD K+ H++ LN +  NP+C G EG++ AY   L+ ++L GPT FSP+I H++     A  S S   Y+VLLI+TDG + D   T++A+V+ S LP+S+I+VGVG   F  ME LD D  +L   S E A RD VQFV  R++  V     D +  +K A   LAK VLAELP QV +Y  ++
Sbjct:   70 FSRKLVMEYRFEEVQKLKFALFDEDAPSAKLVDHDFLGEITSTLGQIV-SHRTLTRPLLMQDDRPAGRGTITISA-----EEITDNRIITLSMAGRKLDKMDLFGKSDPYLEIYKQSPDGTWMLVHRTEVVRNTLDPTWKPFTLHLQVLCNGDLEK--NINAVCYDWDRHGSPD-------LIGEFYANIIRLKEATGSMEVVEFECINNKKKQKKKSYKNSGIIICKSCKISRDYTFLDYIFGGCQLHFTVGIDFTASNGNPRDASSLHYISPTGMNDYLAAIWAVGQIIQDYDTDKLFPALGFGAQLPPDCKVHHDFALNFNPSNPFCTGIEGIVAAYHFCLQNIRLYGPTNFSPIINHVASFAHTASGSASASEYYVLLIITDGVISDMEATREAIVKASRLPMSVIIVGVGNADFEAMEVLDSDDRVLTAPSGEAATRDIVQFVPFRQFRSV-----DRLLINKAAKEELAKSVLAELPGQVVQYFRQR 542          
BLAST of Copine-3 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007777.1 (pep scaffold:Pmarinus_7.0:GL477373:3581:22444:1 gene:ENSPMAG00000006999.1 transcript:ENSPMAT00000007777.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 250.366 bits (638), Expect = 5.341e-75
Identity = 172/483 (35.61%), Postives = 273/483 (56.52%), Query Frame = 1
Query:  280 ISVETGGYIHSRDTIKTER-KSGHDITFDAKLCIEYLFEEKQMIIIEIFE-----YDITQDGDNLLGEVDCSIGRVIHSGGVVLKPLEITDEFKTTLGPLSPEVGIYVEEDLTAKENIELKIRGIGLAKTEIFGKTDPYLMIFRCNNRSRYVQCYRTEVLKNTQNPDWSPIVVSYERLCNNDLNSVLCLRVYCGDGTLKESEEVDIACDQLVGEIKVTARELIQMRRMEEKQFELINPXXXXXXXSYLNSGIISVRAQKTNSEPTFLDFMFQGLELNFIV--AIDLTLSNGDSSLPSSLHFMDCSLTNEYSVAIQAVLEILQEYDNDELFPAFGFGARVPPDYKICHEYPLNGDFENPYCRGAEGVIHAYQQTLKEVKLAGPTCFSPVIRHISRL---AKASESGKHYFVLLILTDGSVDDWVETKKAVVETSYLPXXXXXXXXXXXKFSDMETLDQDFGLLMV-SNEKACRDNVQFVKMRRY 1692
            + +E GG     D  +TE+ ++  +  F  +L I+Y FE+ Q +   +++     YD+T D  + LG+++C++ +V+ S  +  +PL + +      G ++      V +++     + L++    L K ++FGK+DPYL  F+  +   +   +RTEV+KN  NP W P  +  + LCN DL   +  RV C D     S +       L+GE K   + L Q  +  + +F +I+P+KKKKKK+Y  SG++ V++ +T  E +FLD++  G ++NF V  A+   L+ GD    + L           + A+ +   I   +  D+LFPAFGFGA++PP++++ HE+PLN +  NPYC G +G++  Y+  L +V+L GPT FSP+I H++R    A    +   YFVLLI+TDG + D  ET+ AVV+ S LP+S+I+VGVG   FS ME LD D G+L   S E A RD VQFV  R +
Sbjct:   64 VLIEAGGTWSEVD--RTEQIQNCQEPAFSKRLQIDYCFEQVQKLRFGVYDIDNKTYDLTDD--DFLGQLECNLAQVVSSKKMT-RPLLLKNGKPAGKGQIT-----IVADEIKDNRVLALQVDARNLDKKDMFGKSDPYLEFFKMADDGTWQMVHRTEVIKNNLNPTWRPFSIPLQALCNGDLERDV--RVVCYDYDSDGSHD-------LIGEFKTNVKNLQQAEK-GQVEFAVIHPEKKKKKKNYKGSGLVIVKSCRTEVEYSFLDYIMGGCQINFTVRSALRSCLTLGDIHRINLLTLHIPWPLLPLNNALSSFNGIKSHHLQDKLFPAFGFGAQIPPNWQVSHEFPLNFNPANPYCNGVQGIVDMYKVCLPQVRLYGPTNFSPIINHVARFAAAALQQPAATQYFVLLIVTDGVISDMDETRLAVVQASRLPMSLIIVGVGNADFSAMEFLDGDGGVLKAPSGEPAARDIVQFVPFRDF 526          
BLAST of Copine-3 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000748.1 (pep scaffold:Pmarinus_7.0:GL477446:179420:193439:1 gene:ENSPMAG00000000673.1 transcript:ENSPMAT00000000748.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 211.075 bits (536), Expect = 6.066e-62
Identity = 143/386 (37.05%), Postives = 208/386 (53.89%), Query Frame = 1
Query:  658 FGKTDPYLMIFRCNNRSRYVQCYRTEVLKNTQNPDWSPIVVSYERLCNNDLNSVLCLRVYCGDGTLKESEEVDIACDQLVGEIKVTARELIQMRRMEEKQFELINPXXXXXXXSYLNSGIISVRAQKTNSEPTFLDFMFQGLELNFIVAIDLTLSNGDSSLPSSLHFMDCSLTNEYSVAIQAVLEILQEYDNDELFPAFGFGARVPPDYKICHEYPLNGDFENPYCRGAEGVIHAYQQTLKEVKLAGPTCFSPVIRHISRLAK----ASESGKHYFVLLILTDGSVDDWVETKKAVVETSYLPXXXXXXXXXXXKFSDMETLDQDFGLLMV-SNEKACRDNVQFVKMRRYLRVAADGSDNIRWSKVALAKDVLAELPYQVNEYMHR 1800
            FGK+DP+L +++  +  ++   YRTEV KNT NP W  IV++ + LC  D N    ++V C D                +GE  VT  +L Q +      F+L+ P   K   +Y NSG + V       + TFLD++  G +L F +AID T SN   S   SLH    +  N+Y + I+AV   LQ YD D+ FPA+GFGA++P + K+  ++PL  +  NP C G + +I AY+  L +VKL+ P   +PVI  ++  AK     S+    Y +L I+TDG V D   T++A+V+ S LP+SI++VGVG   F D+  LD D  +L   S E A RD VQFV    YL  A D  +          + V+ E+P+QV +Y H+
Sbjct:    4 FGKSDPFLELYKQTSIGKWKLVYRTEVHKNTLNPRWKNIVLNLQSLC--DGNIAKPIKVVCADWNRNGRSNP-------IGECIVTVMQLNQAKLNNTVMFDLVLPGNVKNS-NYKNSGQLVVVLCTICRQYTFLDYIRGGCKLQFSMAIDFTASNKPPSQLDSLHHTGFNDANQYLMVIRAVGGTLQYYDADKQFPAYGFGAQLPSEEKVSQDFPLTLNANNPNCDGVQALIKAYKSCLTKVKLSEPANLAPVINRVATAAKRIKFQSKLAHEYHILFIITDGEVKDMPATREAIVQASKLPLSIVLVGVGSNDFRDLVELDSDDAILTAPSGENAFRDIVQFVP---YLDFARDPVEK-------FLEQVMEEIPHQVEQYFHQ 369          
BLAST of Copine-3 vs. Ensembl Sea Lamprey
Match: cpne2 (copine II [Source:ZFIN;Acc:ZDB-GENE-030131-7896])

HSP 1 Score: 187.963 bits (476), Expect = 3.675e-55
Identity = 111/238 (46.64%), Postives = 148/238 (62.18%), Query Frame = 1
Query: 1099 VAIDLTLSNGDSSLPSSLHFMDCSLTNEYSVAIQAVLEILQEYDNDELFPAFGFGARVPPDYKICHEYPLNGDFENPYCRGAEGVIHAYQQTLKEVKLAGPTCFSPVIRHI---SRLAKASESGKHYFVLLILTDGSVDDWVETKKAVVETSYLPXXXXXXXXXXXKFSDMETLDQDFGLLMV-SNEKACRDNVQFVKMRRYLRVAADGSDNIRWSKVALAKDVLAELPYQVNEYMHR 1800
            V I  + SNGD   PSSLH +  + TNEY  A+ AV +++Q+YD D+ FPA GFGA++PP++++ HE+ LN +  NP+C G EG++ AY   L +V+L GPT FSP+I H+   +  A    +   YFVLLI+TDG + D  ET+ AVV+ S LP+S+I+VGVG   FS ME LD D G+L   S E A RD VQFV  R +              K ALAK VLAE+P QV  Y  +
Sbjct:    1 VGIHFSASNGDPRDPSSLHHISPTGTNEYLAAVWAVGQVIQDYDADKQFPALGFGAQLPPEWEVSHEFALNFNPLNPFCTGVEGIVQAYMACLPQVRLYGPTNFSPIINHVARFAAAAAQQPAATQYFVLLIVTDGVISDMDETRLAVVQASRLPMSLIIVGVGSADFSAMEFLDGDGGVLKAPSGEPAARDIVQFVPFRDFRNA----------PKEALAKAVLAEVPGQVVTYFKQ 228          
BLAST of Copine-3 vs. Ensembl Sea Lamprey
Match: cpne2 (copine II [Source:ZFIN;Acc:ZDB-GENE-030131-7896])

HSP 1 Score: 83.9593 bits (206), Expect = 2.694e-18
Identity = 54/167 (32.34%), Postives = 86/167 (51.50%), Query Frame = 1
Query:  358 FDAKLCIEYLFEEKQMIIIEIFEYDI----TQDGDNLLGEVDCSIGRVIHSGGVVLKPLEITDEFKTTLGPLSPEVGIYVEEDLTAKENIELKIRGIGLAKTEIFGKTDPYLMIFRCNNRSRYVQCYRTEVLKNTQNPDWSPIVVSYERLCNNDLNSVLCLRVYCGD 846
            F  K  I+Y FEE Q +   I++ D      QD D  LG++  ++G+V+ S  +  + L + D       P    +   + E++    +++L   GI L K + FGK+DPYL  F+  +   +V  +RTEV+ NT NP W P  ++ + LC  DL+    +RV C D
Sbjct:   58 FAHKFQIDYHFEEVQKLRFAIYDLDSPSKRLQDHD-FLGDLTLTLGQVVSSKKLS-RALVLKDG-----RPAGKGIIQVLAEEMKDNRHLQLLFEGIKLDKKDFFGKSDPYLEFFKKGDDGSWVLVHRTEVVLNTLNPSWRPFTLAVQSLCGGDLDR--SVRVTCYD 215          
BLAST of Copine-3 vs. Ensembl Nematostella
Match: EDO44352 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RW53])

HSP 1 Score: 315.849 bits (808), Expect = 2.054e-99
Identity = 207/490 (42.24%), Postives = 283/490 (57.76%), Query Frame = 1
Query:  358 FDAKLCIEYLFEEKQMIIIEIFEYDIT----QDGDNLLGEVDCSIGRVIHSGGVVLKPLEITDEFKTTLGPLSPEVGIYVEEDLTAKENIELKIRGIGLAKTEIFGKTDPYLMIFRCNNRSRYVQCYRTEVLKNTQNPDWSPIVVSYERLCNNDLNSVLCLRVYCGDGTLKESEEVDIACDQLVGEIKVTARELIQMRRMEEKQFELINPXXXXXXXSYLNSGIISVRAQKTNSEPTFLDFMFQGLELNFIVAIDLTLSNGDSSLPSSLHFMDCSLTNEYSVAIQAVLEILQEYDNDELFPAFGFGARVPPDYKICHEYPLNGDFENPYCRGAEGVIHAYQQTLKEVKLAGPTCFSPVIRHISRLAKASE---SGKHYFVLLILTDGSVDDWVETKKAVVETSYLPXXXXXXXXXXXKFSDMETLDQDFGLLMVSNEKACRDNVQFVKMRRYL-RVAADGSDNIRWSKVALAKDVLAELPYQVNEYMHRK 1803
            F  K  I Y FEE Q +  ++++ D      QD D  +GE++C++G ++   G  L                  E  +  EE    K+   L+ RG  L K + FGK+DP+L+ +RCN  + +   +RTEV+KNT NP W P  V    LCN D++    +R+ C D     S +       L+G    T REL     +    FEL NPKK+ KKKSY NSG I +   K   +PTFLDF+  G +++FIVAID T SNG+    +SLHF++    N+Y  A+ +V  I Q+YD+D+LFPAFGFGAR+PP++++ HE+ LNG+ +NP+C   EGVI +Y  +++ V+L GPT FSP+IR    LAK SE    G+ YFVLLILTDG + D  +TK A+V+ + LPVSII+VGVGG  F  ME LD D   L      A RD VQFV  R YL +   D +   R     LAKDVL ELP Q+ +YM ++
Sbjct:   65 FVKKFTIHYFFEEIQKLRFQVYDIDKKSSRLQDHD-FIGEIECTLGSIVGENGGQL------------------EKALLCEEVSQCKDVATLQFRGHKLDKKDFFGKSDPFLVFYRCNEDNSFTAVHRTEVVKNTLNPTWKPFSVPARALCNGDIDR--SIRIECYDWDRDGSHD-------LIGIFSTTLRELTSNPNL---TFELKNPKKQAKKKSYKNSGTIILLQSKLEQQPTFLDFIKGGTQISFIVAIDFTASNGNPQNSNSLHFLNPYEPNQYVKALTSVGAICQDYDSDKLFPAFGFGARLPPNWEVSHEFALNGNPQNPFCERVEGVISSYFHSIQRVQLYGPTNFSPIIRRTVALAKESERQKPGEEYFVLLILTDGIISDMEQTKAAIVDAASLPVSIIIVGVGGADFEAMEELDGDEVRLSSRGRLAERDIVQFVPFRDYLDKCYGDITSGAR-----LAKDVLEELPDQLTDYMKKR 518          
BLAST of Copine-3 vs. Ensembl Nematostella
Match: EDO39500 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S9X6])

HSP 1 Score: 301.212 bits (770), Expect = 7.850e-94
Identity = 188/500 (37.60%), Postives = 284/500 (56.80%), Query Frame = 1
Query:  325 KTER-KSGHDITFDAKLCIEYLFEEKQMIIIEIFEYDITQ---DGDNLLGEVDCSIGRVIHSGGVVLKPLEITDEFKTTLGPLSPEVGIYVEEDLTAKENIELKIRGIGLAKTEIFGKTDPYLMIFRCNNRSRYVQCYRTEVLKNTQNPDWSPIVVSYERLCNNDLNSVLCLRVYCGDGTLKESEEVDIACDQLVGEIKVTARELIQMRRMEEKQFELINPXXXXXXXSYLNSGIISVRAQKTNSEPTFLDFMFQGLELNFIVAIDLTLSNGDSSLPSSLHFMDCSLTNEYSVAIQAVLEILQEYDNDELFPAFGFGARVPPDYKICHEYPLNGDFENPYCRGAEGVIHAYQQTLKEVKLAGPTCFSPVIRHISRLA-KASESGK--HYFVLLILTDGSVDDWVETKKAVVETSYLPXXXXXXXXXXXKFSDMETLDQDFGLLMVSNEKACRDNVQFVKMRRYLRVAADGSDNIRWSKVALAKDVLAELPYQVNEYMHRK 1803
            +TER K+  +  F   + ++Y FE  Q +   +F+ D      D D+ LG ++C++G+++ S     K LEI      T       + IY EE   A E ++L  R   L   +  GK+DP+L + +       +  +RTEV+KN  NP W    +  + LC+ D ++ +  R+ C D     S +       L+G    + R+L+++R+      +LINPKKK KKK Y+NSG++ +   +     TFLD++  G ++NF V +D T SNG+ S P SLH+++    NEY  A+ +V E+ Q+YD+D+LFPAFGFGA++PP++++ HE+ LN +  NPYC G  GV+ AYQ  +++V+L GPT  SP+I H++  A +A++ G    YFVLL++TDG + D   TK A+V  S LP+S+I+VGVG   F+DM  LD D G L   +E+A RD VQFV  R          D        LAK VLAE+P Q  EY + +
Sbjct:   46 RTERVKNNLNPDFSKAISVDYYFELVQKLKFSVFDVDNATKQLDDDDFLGSIECTLGQIV-SKKSFTKHLEIKGRQVGT-------ITIYAEEMKGANEIVKLTFRATNLDNKDFMGKSDPFLELLKLKPDGGTLLVHRTEVIKNNLNPTWKVFSLPIQSLCSADYDATI--RIDCHDYDGDGSHD-------LIGIANTSLRQLLELRQ-SGSGLDLINPKKKAKKKKYVNSGVLYISGCEVIHHNTFLDYVMGGCQINFTVGVDFTASNGNPSTPQSLHYINPYEPNEYVNALVSVGEVCQDYDSDKLFPAFGFGAKIPPNFQVSHEFALNFNPSNPYCEGIPGVVAAYQACIRQVQLYGPTNASPIINHVASFAQRAAQDGTAGAYFVLLLITDGVLSDMEATKLAIVRASRLPMSLIIVGVGSADFTDMNELDADEGTLRAGHERAERDIVQFVPFR----------DFKTQPPAMLAKHVLAEVPKQAQEYFNSR 517          
BLAST of Copine-3 vs. Ensembl Nematostella
Match: EDO45927 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RRD6])

HSP 1 Score: 276.944 bits (707), Expect = 1.047e-84
Identity = 186/498 (37.35%), Postives = 276/498 (55.42%), Query Frame = 1
Query:  325 KTER-KSGHDITFDAKLCIEYLFEEKQMIIIEIFEYDITQDG---DNLLGEVDCSIGRVIHSGGVVLKPLEITDEFKTTLGPLSPEVGIYVEEDLTAKENIELKIRGIGLAKTEIFGKTDPYLMIFRCNNRSRYVQCYRTEVLKNTQNPDWSPIVVSYERLCNNDLNSVLCLRVYCGDGTLKESEEVDIACDQLVGEIKVTARELIQMRRM-EEKQFELINPXXXXXXXSYLNSGIISVRAQKTNSEPTFLDFMFQGLELNFIVAIDLTLSNGDSSLPSSLHFMDCSLTNEYSVAIQAVLEILQEYDNDELFPAFGFGARVPPDYKICHEYPLNGDFENPYCRGAEGVIHAYQQTLKEVKLAGPTCFSPVIRHISRLAKASESGK----HYFVLLILTDGSVDDWVETKKAVVETSYLPXXXXXXXXXXXKFSDMETLDQDFGLLMVSNEKACRDNVQFVKMRRYLRVAADGSDNIRWSKVALAKDVLAELPYQVNEY 1791
            +TER ++  +  F   + ++Y FEE Q +   +++ D         + LGE+ C++G+++ S                                 T   N+++         T+ FGK+DPYL   R      +V  +RTEV+ N  NP W PI +S ++LCN D + VL +  Y  D         D     L+G    T REL   ++   E Q+  IN KK+KKKK+Y NSG+I + + +     +FLDF+  G ++NF V ID T SNG+ + P+SLH+++    NEY  A+ AV EI+Q+YD+D+LFPAFGFGA+VPP+  + H++ LN +  NP+C G +G+I AYQQ +++V L GPT  +P+I +++  A+A+        +Y++LLILTDG + D  +TK+A+V+ S LP+SII+VGVG   F  ME LD D GLL      A RD VQFV  R++  +          S  ALAK+VLAE+P QV  Y
Sbjct:   64 RTERLENTLNPNFSTTIVVDYFFEELQKLKFMVYDIDSASGSLKNADFLGEMQCTLGQLVSSA--------------------------------TYTHNLKIPSGKPAGNMTDFFGKSDPYLEFSRAKEDGSFVVVHRTEVVSNNLNPKWKPIHISSQQLCNGDYDRVLKVNCYDWD---------DDGSHDLIGTFTTTLRELSTCQQGGAELQWPCINEKKRKKKKNYKNSGVIFLSSCQVVRVASFLDFIQGGCQINFTVGIDFTGSNGNPASPTSLHYINPYAPNEYCQALTAVGEIIQDYDSDKLFPAFGFGAKVPPNNMVSHQFALNFNHTNPFCAGLQGLIEAYQQCVRQVTLYGPTNIAPIISNVAMYAQAAAQQPYASLNYYILLILTDGVISDMDQTKRAIVQASGLPMSIIIVGVGSADFEMMEELDADDGLLRSEGSTAQRDIVQFVPFRKFKNL----------SSAALAKEVLAEVPGQVTGY 510          
BLAST of Copine-3 vs. Ensembl Nematostella
Match: EDO49902 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RF64])

HSP 1 Score: 157.147 bits (396), Expect = 1.464e-41
Identity = 107/348 (30.75%), Postives = 177/348 (50.86%), Query Frame = 1
Query:  571 VGIYVEEDLTAKENIELKIRGIGLAKTEIFGKTDPYLMIFRCNNRSRYVQCYRTEVLKNTQNPDWSPIVVSYERLCNNDLN--SVLCLRVYCGDGTLKESEEVDIACDQLVGEIKVTARELIQMRRMEEKQFELINPXXXXXXXSYLNSGIISVRAQKTNSEPTFLDFMFQGLELNFIVAIDLTLSNGDSSLPSSLHFMDCSLTNEYSVAIQAVLEILQEYDNDELFPAFGFGARVPPDYKICHEYPLNGDFENPYCRGAEGVIHAYQQTLKEVKLAGPTCFSPVIRHISRLA--KASESGKHYFVLLILTDGSVDDWVETKKAVVETSYLPXXXXXXXXXXXKFSDM 1602
            + ++ EE  T+  N+  +I G+ L K  +  K D +  + R      Y   YR+E++  T +P WSP  +  ++LCN ++   +V+    Y   G            + L+   +     LI  R +  K  +L+ P+K +K +    +G + +     +   + +D++  G ++    AID TLSNGD S  SSLH + C   NEY  A++A+  +L  YD D+  P F FGA+       C  + LNGD   P     E +I  Y ++L  +KL GPT   PVI+ ++  A  + S+  +HY V +++ DG  +D  +TK+ +++ S LP+SI+VVGVG   F+ M
Sbjct:  121 IKLFYEEVHTSLTNVRFQISGVNLEKRSLLSKWDVFFELERLLPGGFYHPVYRSEIVARTLDPRWSPFDIYLQKLCNEEVTREAVISCWHYSSSGA-----------NTLIASARCPVGHLIN-RSI--KVLQLVKPQKTQKARRAGTAGSLRIDHCHVDKHFSLVDYIRGGCDVTIACAIDFTLSNGDPSCRSSLHTLSCLYQNEYIGALRALGPVLMHYDEDKQIPTFAFGAKSKHGIPYC--FALNGDESEPEISSIETLIDTYTRSLTTIKLGGPTYLVPVIKRLADYATRELSQDSQHYLVAMVIMDGVANDLDDTKEQIIQVSGLPLSIVVVGVGPADFTAM 452          
BLAST of Copine-3 vs. Ensembl Nematostella
Match: EDO26801 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7TB16])

HSP 1 Score: 120.939 bits (302), Expect = 2.515e-30
Identity = 79/194 (40.72%), Postives = 112/194 (57.73%), Query Frame = 1
Query:  652 EIFGKTDPYLMIFRCNNRSRYVQCYRTEVLKNTQNPDWSPIVVSYERLCNNDLNSVLCLRVYCGDGTLKESEEVDIACDQLVGEIKVTARELIQMRRM-EEKQFELINPXXXXXXXSYLNSGIISVRAQKTNSEPTFLDFMFQGLELNFIVAIDLTLSNGDSSLPSSLHFMDCSLTNEYSVAIQAVLEILQEYD 1230
            + FGK+DPYL   R      +V  +RTEV+ N  NP W PI +S ++LCN D + VL +  Y  D         D     L+G    T REL   ++   E Q+  IN KK+KKKK+Y NSG+I + + +     +FLDF+  G ++NF V ID T SNG+ + P+SLH+++    NEY  A+ AV EI+Q+YD
Sbjct:  107 DFFGKSDPYLEFSRAKEDGSFVVVHRTEVVSNNLNPKWKPIHISSQQLCNGDYDRVLKVNCYDWD---------DDGSHDLIGTFTTTLRELSTCQQGGAELQWPCINEKKRKKKKNYKNSGVIFLSSCQVVRVASFLDFIQGGCQINFTVGIDFTGSNGNPASPTSLHYINPYAPNEYCQALTAVGEIIQDYD 291          
BLAST of Copine-3 vs. Ensembl Medaka
Match: cpne5a (copine-5 [Source:NCBI gene;Acc:101166794])

HSP 1 Score: 329.717 bits (844), Expect = 7.881e-104
Identity = 194/488 (39.75%), Postives = 290/488 (59.43%), Query Frame = 1
Query:  358 FDAKLCIEYLFEEKQMIIIEIFEYDITQDGD----NLLGEVDCSIGRVIHSGGVVL-KPLEITDEFKTTLGPLSPEVGIYVEEDLTAKENIELKIRGIGLAKTEIFGKTDPYLMIFRCNNRSRYVQCYRTEVLKNTQNPDWSPIVVSYERLCNNDLNSVLCLRVYCGDGTLKESEEVDIACDQLVGEIKVTARELIQMRRMEEKQFELINPXXXXXXXSYLNSGIISVRAQKTNSEPTFLDFMFQGLELNFIVAIDLTLSNGDSSLPSSLHFMDCSLTNEYSVAIQAVLEILQEYDNDELFPAFGFGARVPPDYKICHEYPLNGDFENPYCRGAEGVIHAYQQTLKEVKLAGPTCFSPVIRHISRLAKASESGKHYFVLLILTDGSVDDWVETKKAVVETSYLPXXXXXXXXXXXKFSDMETLDQDFGLLMVSNEKACRDNVQFVKMRRYLRVAADGSDNIRWSKVALAKDVLAELPYQVNEYMHRKT 1806
            F  K  ++Y FEEKQ +  ++++ D ++  D    + LG+V C++G ++ S    L KPL          G     + +  EE    ++   ++     L K + FGK+DP+++ +R N    +  C++TEV+KNT NP W P  +    LCN D +  + + VY  D                +GE   + +EL + +  E   +E++N KKK KKK Y+NSG +S+ +    SE TFLD++  G +++F VAID T SNG+ S  +SLH+M+    N Y++A++AV EI+Q+YD+D++FPA GFGA++PPD ++ HE+PLNG+ ENPYC G EG++ AY Q+LK V+L GPT F+PV+ H++R A A E G  YF+LLI+TDG + D  +TK+A+V  + LP+SII+VGVG  +F  M  LD D   +    + A RD VQFV  R Y+    D + N   S   LAKDVLAE+P Q+  YM  + 
Sbjct:   81 FVRKYILDYFFEEKQNLRFDVYDID-SKSPDLGKHDFLGQVYCTLGEIVGSPASRLEKPL------GGIPGKTCGTIILSAEELGNCRDYATMQFCANKLDKKDFFGKSDPFMVFYRSNEDGTFTICHKTEVVKNTLNPMWQPFSIPVRALCNGDYDRTIKVEVYDWDRD---------GSHDFIGEFSTSYKELCRGQS-ESNVYEVVNAKKKLKKKRYINSGTVSLLSFSVESEHTFLDYIKGGTQIHFTVAIDFTASNGNPSQSTSLHYMNPYQMNAYAMALKAVGEIIQDYDSDKMFPALGFGAKLPPDGRVSHEFPLNGNVENPYCNGMEGILEAYHQSLKLVQLYGPTNFAPVVNHVARYAAAVEDGSQYFILLIITDGVISDMAQTKEAIVNAAKLPMSIIIVGVGQAEFDAMVELDGDDVRISSRGKLAERDIVQFVPFRDYM----DRTGNHVLSMARLAKDVLAEIPDQLISYMKSRA 547          
BLAST of Copine-3 vs. Ensembl Medaka
Match: cpne5a (copine-5 [Source:NCBI gene;Acc:101166794])

HSP 1 Score: 329.717 bits (844), Expect = 9.864e-104
Identity = 194/492 (39.43%), Postives = 289/492 (58.74%), Query Frame = 1
Query:  358 FDAKLCIEYLFEEKQMIIIEIFEYDITQ--------DGDNLLGEVDCSIGRVIHSGGVVL-KPLEITDEFKTTLGPLSPEVGIYVEEDLTAKENIELKIRGIGLAKTEIFGKTDPYLMIFRCNNRSRYVQCYRTEVLKNTQNPDWSPIVVSYERLCNNDLNSVLCLRVYCGDGTLKESEEVDIACDQLVGEIKVTARELIQMRRMEEKQFELINPXXXXXXXSYLNSGIISVRAQKTNSEPTFLDFMFQGLELNFIVAIDLTLSNGDSSLPSSLHFMDCSLTNEYSVAIQAVLEILQEYDNDELFPAFGFGARVPPDYKICHEYPLNGDFENPYCRGAEGVIHAYQQTLKEVKLAGPTCFSPVIRHISRLAKASESGKHYFVLLILTDGSVDDWVETKKAVVETSYLPXXXXXXXXXXXKFSDMETLDQDFGLLMVSNEKACRDNVQFVKMRRYLRVAADGSDNIRWSKVALAKDVLAELPYQVNEYMHRKT 1806
            F  K  ++Y FEEKQ +  ++++ D           D ++ LG+V C++G ++ S    L KPL          G     + +  EE    ++   ++     L K + FGK+DP+++ +R N    +  C++TEV+KNT NP W P  +    LCN D +  + + VY  D                +GE   + +EL + +  E   +E++N KKK KKK Y+NSG +S+ +    SE TFLD++  G +++F VAID T SNG+ S  +SLH+M+    N Y++A++AV EI+Q+YD+D++FPA GFGA++PPD ++ HE+PLNG+ ENPYC G EG++ AY Q+LK V+L GPT F+PV+ H++R A A E G  YF+LLI+TDG + D  +TK+A+V  + LP+SII+VGVG  +F  M  LD D   +    + A RD VQFV  R Y+    D + N   S   LAKDVLAE+P Q+  YM  + 
Sbjct:   81 FVRKYILDYFFEEKQNLRFDVYDIDSKSPDLGKHPTDLNDFLGQVYCTLGEIVGSPASRLEKPL------GGIPGKTCGTIILSAEELGNCRDYATMQFCANKLDKKDFFGKSDPFMVFYRSNEDGTFTICHKTEVVKNTLNPMWQPFSIPVRALCNGDYDRTIKVEVYDWDRD---------GSHDFIGEFSTSYKELCRGQS-ESNVYEVVNAKKKLKKKRYINSGTVSLLSFSVESEHTFLDYIKGGTQIHFTVAIDFTASNGNPSQSTSLHYMNPYQMNAYAMALKAVGEIIQDYDSDKMFPALGFGAKLPPDGRVSHEFPLNGNVENPYCNGMEGILEAYHQSLKLVQLYGPTNFAPVVNHVARYAAAVEDGSQYFILLIITDGVISDMAQTKEAIVNAAKLPMSIIIVGVGQAEFDAMVELDGDDVRISSRGKLAERDIVQFVPFRDYM----DRTGNHVLSMARLAKDVLAEIPDQLISYMKSRA 552          
BLAST of Copine-3 vs. Ensembl Medaka
Match: cpne5b (copine-8 [Source:NCBI gene;Acc:101170754])

HSP 1 Score: 326.635 bits (836), Expect = 2.737e-103
Identity = 192/486 (39.51%), Postives = 287/486 (59.05%), Query Frame = 1
Query:  358 FDAKLCIEYLFEEKQMIIIEIFEYDITQ---DGDNLLGEVDCSIGRVIHSGGVVL-KPLEITDEFKTTLGPLSPEVGIYVEEDLTAKENIELKIRGIGLAKTEIFGKTDPYLMIFRCNNRSRYVQCYRTEVLKNTQNPDWSPIVVSYERLCNNDLNSVLCLRVYCGDGTLKESEEVDIACDQLVGEIKVTARELIQMRRMEEKQFELINPXXXXXXXSYLNSGIISVRAQKTNSEPTFLDFMFQGLELNFIVAIDLTLSNGDSSLPSSLHFMDCSLTNEYSVAIQAVLEILQEYDNDELFPAFGFGARVPPDYKICHEYPLNGDFENPYCRGAEGVIHAYQQTLKEVKLAGPTCFSPVIRHISRLAKASESGKHYFVLLILTDGSVDDWVETKKAVVETSYLPXXXXXXXXXXXKFSDMETLDQDFGLLMVSNEKACRDNVQFVKMRRYLRVAADGSDNIRWSKVALAKDVLAELPYQVNEYMHRK 1803
            F  K  ++Y FEEKQ +  ++++ D         + LG+V C++G ++ S    L KPL          G     + +  EE    +++  ++     L K + FGK+DP+++ +R N    +  C++TEV+KNT NP W P  +    LCN D +  + + VY  D                +G+   + REL + +  +   +E+IN KKK KKK Y+NSG +++ +    SE TFLD++  G ++NF VAID T SNG+ S  +SLH+M+    N Y++A++AV EI+Q+YD+D++FPA GFGA++PPD ++ HE+PLNG+ ENPYC G EG++ AY ++LK V+L GPT F+PV+ H++R A A + G  YFVLLI+TDG + D  +TK+A+V  + LP+SII+VGVG  +F  M  LD D   +    + A RD VQFV  R Y+    D + N   S   LAKDVLAE+P Q   YM  +
Sbjct:   31 FVRKYILDYFFEEKQNLRFDLYDVDSKSPDLSKHDFLGQVFCTLGEIVGSPASRLEKPL------GGIPGKKCGTIILSAEELSNCRDSATMQFCANKLDKKDFFGKSDPFMVFYRSNEDGTFTICHKTEVVKNTLNPVWQPFTIPVRALCNGDYDRTIKVEVYDWDRD---------GSHDFIGDFTTSYRELARGQS-QFNVYEVINTKKKMKKKKYVNSGTVTLLSFSVESEFTFLDYIKGGTQINFTVAIDFTASNGNPSQSTSLHYMNPYQLNAYAMALKAVGEIIQDYDSDKMFPALGFGAKLPPDGRVSHEFPLNGNLENPYCNGIEGILEAYHESLKTVQLYGPTNFAPVVNHVARYAAAVQDGSQYFVLLIITDGVISDMAQTKEAIVNAAKLPMSIIIVGVGQAEFDAMVELDGDDIRVSSRGKLAERDIVQFVPFRDYM----DRTGNHVLSMARLAKDVLAEIPDQFISYMKSR 496          
BLAST of Copine-3 vs. Ensembl Medaka
Match: CPNE8 (copine 8 [Source:NCBI gene;Acc:101158741])

HSP 1 Score: 325.865 bits (834), Expect = 2.139e-102
Identity = 197/488 (40.37%), Postives = 288/488 (59.02%), Query Frame = 1
Query:  358 FDAKLCIEYLFEEKQMIIIEIFEYDITQDGDNL-----LGEVDCSIGRVIHSGGVVL-KPLEITDEFKTTLGPLSPEVGIYVEEDLTAKENIELKIRGIGLAKTEIFGKTDPYLMIFRCNNRSRYVQCYRTEVLKNTQNPDWSPIVVSYERLCNNDLNSVLCLRVYCGDGTLKESEEVDIACDQLVGEIKVTARELIQMRRMEEKQFELINPXXXXXXXSYLNSGIISVRAQKTNSEPTFLDFMFQGLELNFIVAIDLTLSNGDSSLPSSLHFMDCSLTNEYSVAIQAVLEILQEYDNDELFPAFGFGARVPPDYKICHEYPLNGDFENPYCRGAEGVIHAYQQTLKEVKLAGPTCFSPVIRHISRLAKASESGKHYFVLLILTDGSVDDWVETKKAVVETSYLPXXXXXXXXXXXKFSDMETLDQDFGLLMVSNEKACRDNVQFVKMRRYLRVAADGSDNIRWSKVALAKDVLAELPYQVNEYMHRK 1803
            F  K  ++Y FEE+Q + +++  YD+     NL     LG+  C++G ++ S G  L KPL          G     + +  EE    +E++ ++  G  L K + FGK+DP+L+ +R N    +  C++TEV+KNT NP W    +    LCN D +  + + VY  D                +GE   + REL + +  +   +E++NPKKK KKK YLNSG +++ +   + E TFLD++  G ++NF VAID T SNG+ + P+SLH+M     N Y++A++AV EI+Q+YD+D++FPA GFGA++PPD ++ HE+ LNG+ +NPYC G +GV+ AY QTLK V+L GPT F+PVI H++R A + + G  YFVLLI+TDG + D   TK+A+V  S LP+SI++VGVG  +F  M  LD D   +      A RD VQFV  R Y+    D + N   S   LAKDVLAE+P Q   YM  +
Sbjct:   77 FVRKFILDYFFEERQNLRLDL--YDVDSKSANLSKHDFLGQAYCTLGEIVGSLGSRLEKPL------GGIPGKKCGTIIVKAEELNNCRESVMMQFCGNKLDKKDFFGKSDPFLIFYRSNEDGTFTICHKTEVVKNTLNPVWQAFKIPVRALCNGDYDRTIKVEVYDWDRD---------GSHDFIGEFSTSYRELSRGQS-QFNVYEVVNPKKKGKKKKYLNSGTVTLLSFLVDIEVTFLDYIKGGTQINFTVAIDFTASNGNPAQPTSLHYMSPYQLNTYAMALKAVGEIIQDYDSDKMFPALGFGAKLPPDGRVSHEFALNGNPQNPYCDGIDGVMEAYYQTLKSVQLYGPTNFAPVINHVARYAASVKDGSQYFVLLIITDGVITDMALTKEAIVNASGLPMSILIVGVGPAEFDAMVELDGDEVRISSRGRLAERDIVQFVPFRDYM----DRTGNHVLSMARLAKDVLAEIPDQFLSYMRTR 542          
BLAST of Copine-3 vs. Ensembl Medaka
Match: cpne5b (copine-8 [Source:NCBI gene;Acc:101170754])

HSP 1 Score: 327.405 bits (838), Expect = 2.838e-102
Identity = 192/486 (39.51%), Postives = 287/486 (59.05%), Query Frame = 1
Query:  358 FDAKLCIEYLFEEKQMIIIEIFEYDITQ---DGDNLLGEVDCSIGRVIHSGGVVL-KPLEITDEFKTTLGPLSPEVGIYVEEDLTAKENIELKIRGIGLAKTEIFGKTDPYLMIFRCNNRSRYVQCYRTEVLKNTQNPDWSPIVVSYERLCNNDLNSVLCLRVYCGDGTLKESEEVDIACDQLVGEIKVTARELIQMRRMEEKQFELINPXXXXXXXSYLNSGIISVRAQKTNSEPTFLDFMFQGLELNFIVAIDLTLSNGDSSLPSSLHFMDCSLTNEYSVAIQAVLEILQEYDNDELFPAFGFGARVPPDYKICHEYPLNGDFENPYCRGAEGVIHAYQQTLKEVKLAGPTCFSPVIRHISRLAKASESGKHYFVLLILTDGSVDDWVETKKAVVETSYLPXXXXXXXXXXXKFSDMETLDQDFGLLMVSNEKACRDNVQFVKMRRYLRVAADGSDNIRWSKVALAKDVLAELPYQVNEYMHRK 1803
            F  K  ++Y FEEKQ +  ++++ D         + LG+V C++G ++ S    L KPL          G     + +  EE    +++  ++     L K + FGK+DP+++ +R N    +  C++TEV+KNT NP W P  +    LCN D +  + + VY  D                +G+   + REL + +  +   +E+IN KKK KKK Y+NSG +++ +    SE TFLD++  G ++NF VAID T SNG+ S  +SLH+M+    N Y++A++AV EI+Q+YD+D++FPA GFGA++PPD ++ HE+PLNG+ ENPYC G EG++ AY ++LK V+L GPT F+PV+ H++R A A + G  YFVLLI+TDG + D  +TK+A+V  + LP+SII+VGVG  +F  M  LD D   +    + A RD VQFV  R Y+    D + N   S   LAKDVLAE+P Q   YM  +
Sbjct:  139 FVRKYILDYFFEEKQNLRFDLYDVDSKSPDLSKHDFLGQVFCTLGEIVGSPASRLEKPL------GGIPGKKCGTIILSAEELSNCRDSATMQFCANKLDKKDFFGKSDPFMVFYRSNEDGTFTICHKTEVVKNTLNPVWQPFTIPVRALCNGDYDRTIKVEVYDWDRD---------GSHDFIGDFTTSYRELARGQS-QFNVYEVINTKKKMKKKKYVNSGTVTLLSFSVESEFTFLDYIKGGTQINFTVAIDFTASNGNPSQSTSLHYMNPYQLNAYAMALKAVGEIIQDYDSDKMFPALGFGAKLPPDGRVSHEFPLNGNLENPYCNGIEGILEAYHESLKTVQLYGPTNFAPVVNHVARYAAAVQDGSQYFVLLIITDGVISDMAQTKEAIVNAAKLPMSIIIVGVGQAEFDAMVELDGDDIRVSSRGKLAERDIVQFVPFRDYM----DRTGNHVLSMARLAKDVLAEIPDQFISYMKSR 604          
BLAST of Copine-3 vs. Planmine SMEST
Match: SMESG000064685.1 (SMESG000064685.1)

HSP 1 Score: 1268.83 bits (3282), Expect = 0.000e+0
Identity = 631/633 (99.68%), Postives = 633/633 (100.00%), Query Frame = 1
Query:  193 MALNGKPKVLISLIVNNLSGTEGKLYWANISVETGGYIHSRDTIKTERKSGHDITFDAKLCIEYLFEEKQMIIIEIFEYDITQDGDNLLGEVDCSIGRVIHSGGVVLKPLEITDEFKTTLGPLSPEVGIYVEEDLTAKENIELKIRGIGLAKTEIFGKTDPYLMIFRCNNRSRYVQCYRTEVLKNTQNPDWSPIVVSYERLCNNDLNSVLCLRVYCGDGTLKESEEVDIACDQLVGEIKVTARELIQMRRMEEKQFELINPXXXXXXXSYLNSGIISVRAQKTNSEPTFLDFMFQGLELNFIVAIDLTLSNGDSSLPSSLHFMDCSLTNEYSVAIQAVLEILQEYDNDELFPAFGFGARVPPDYKICHEYPLNGDFENPYCRGAEGVIHAYQQTLKEVKLAGPTCFSPVIRHISRLAKASESGKHYFVLLILTDGSVDDWVETKKAVVETSYLPXXXXXXXXXXXKFSDMETLDQDFGLLMVSNEKACRDNVQFVKMRRYLRVAADGSDNIRWSKVALAKDVLAELPYQVNEYMHRKTKLTNYLENLPTQRSTAVFSSCLRQNCSSDPNSLSLQRTPTLNQSRRMLYNEGNISSQAKSRLLKNTRQYSVDSSLFSKQVSSRKTPPFSRKSNFS 2091
            MALNGKPKVLISLIVNNLSGTEGKLYWANISVETGGYIHSRDTIKTERKSGHDITFDAKLCIEYLFEEKQMIIIEIFEYDITQDGDNLLGEVDCSIGRVIHSGGV+LKPLEIT+EFKTTLGPLSPEVGIYVEEDLTAKENIELKIRGIGLAKTEIFGKTDPYLMIFRCNNRSRYVQCYRTEVLKNTQNPDWSPIVVSYERLCNNDLNSVLCLRVYCGDGTLKESEEVDIACDQLVGEIKVTARELIQMRRMEEKQFELINPKKKKKKKSYLNSGIISVRAQKTNSEPTFLDFMFQGLELNFIVAIDLTLSNGDSSLPSSLHFMDCSLTNEYSVAIQAVLEILQEYDNDELFPAFGFGARVPPDYKICHEYPLNGDFENPYCRGAEGVIHAYQQTLKEVKLAGPTCFSPVIRHISRLAKASESGKHYFVLLILTDGSVDDWVETKKAVVETSYLPVSIIVVGVGGGKFSDMETLDQDFGLLMVSNEKACRDNVQFVKMRRYLRVAADGSDNIRWSKVALAKDVLAELPYQVNEYMHRKTKLTNYLENLPTQRSTAVFSSCLRQNCSSDPNSLSLQRTPTLNQSRRMLYNEGNISSQAKSRLLKNTRQYSVDSSLFSKQVSSRKTPPFSRKSNFS
Sbjct:    1 MALNGKPKVLISLIVNNLSGTEGKLYWANISVETGGYIHSRDTIKTERKSGHDITFDAKLCIEYLFEEKQMIIIEIFEYDITQDGDNLLGEVDCSIGRVIHSGGVILKPLEITNEFKTTLGPLSPEVGIYVEEDLTAKENIELKIRGIGLAKTEIFGKTDPYLMIFRCNNRSRYVQCYRTEVLKNTQNPDWSPIVVSYERLCNNDLNSVLCLRVYCGDGTLKESEEVDIACDQLVGEIKVTARELIQMRRMEEKQFELINPKKKKKKKSYLNSGIISVRAQKTNSEPTFLDFMFQGLELNFIVAIDLTLSNGDSSLPSSLHFMDCSLTNEYSVAIQAVLEILQEYDNDELFPAFGFGARVPPDYKICHEYPLNGDFENPYCRGAEGVIHAYQQTLKEVKLAGPTCFSPVIRHISRLAKASESGKHYFVLLILTDGSVDDWVETKKAVVETSYLPVSIIVVGVGGGKFSDMETLDQDFGLLMVSNEKACRDNVQFVKMRRYLRVAADGSDNIRWSKVALAKDVLAELPYQVNEYMHRKTKLTNYLENLPTQRSTAVFSSCLRQNCSSDPNSLSLQRTPTLNQSRRMLYNEGNISSQAKSRLLKNTRQYSVDSSLFSKQVSSRKTPPFSRKSNFS 633          
BLAST of Copine-3 vs. Planmine SMEST
Match: SMESG000064685.1 (SMESG000064685.1)

HSP 1 Score: 1259.59 bits (3258), Expect = 0.000e+0
Identity = 627/629 (99.68%), Postives = 629/629 (100.00%), Query Frame = 1
Query:  193 MALNGKPKVLISLIVNNLSGTEGKLYWANISVETGGYIHSRDTIKTERKSGHDITFDAKLCIEYLFEEKQMIIIEIFEYDITQDGDNLLGEVDCSIGRVIHSGGVVLKPLEITDEFKTTLGPLSPEVGIYVEEDLTAKENIELKIRGIGLAKTEIFGKTDPYLMIFRCNNRSRYVQCYRTEVLKNTQNPDWSPIVVSYERLCNNDLNSVLCLRVYCGDGTLKESEEVDIACDQLVGEIKVTARELIQMRRMEEKQFELINPXXXXXXXSYLNSGIISVRAQKTNSEPTFLDFMFQGLELNFIVAIDLTLSNGDSSLPSSLHFMDCSLTNEYSVAIQAVLEILQEYDNDELFPAFGFGARVPPDYKICHEYPLNGDFENPYCRGAEGVIHAYQQTLKEVKLAGPTCFSPVIRHISRLAKASESGKHYFVLLILTDGSVDDWVETKKAVVETSYLPXXXXXXXXXXXKFSDMETLDQDFGLLMVSNEKACRDNVQFVKMRRYLRVAADGSDNIRWSKVALAKDVLAELPYQVNEYMHRKTKLTNYLENLPTQRSTAVFSSCLRQNCSSDPNSLSLQRTPTLNQSRRMLYNEGNISSQAKSRLLKNTRQYSVDSSLFSKQVSSRKTPPFSRK 2079
            MALNGKPKVLISLIVNNLSGTEGKLYWANISVETGGYIHSRDTIKTERKSGHDITFDAKLCIEYLFEEKQMIIIEIFEYDITQDGDNLLGEVDCSIGRVIHSGGV+LKPLEIT+EFKTTLGPLSPEVGIYVEEDLTAKENIELKIRGIGLAKTEIFGKTDPYLMIFRCNNRSRYVQCYRTEVLKNTQNPDWSPIVVSYERLCNNDLNSVLCLRVYCGDGTLKESEEVDIACDQLVGEIKVTARELIQMRRMEEKQFELINPKKKKKKKSYLNSGIISVRAQKTNSEPTFLDFMFQGLELNFIVAIDLTLSNGDSSLPSSLHFMDCSLTNEYSVAIQAVLEILQEYDNDELFPAFGFGARVPPDYKICHEYPLNGDFENPYCRGAEGVIHAYQQTLKEVKLAGPTCFSPVIRHISRLAKASESGKHYFVLLILTDGSVDDWVETKKAVVETSYLPVSIIVVGVGGGKFSDMETLDQDFGLLMVSNEKACRDNVQFVKMRRYLRVAADGSDNIRWSKVALAKDVLAELPYQVNEYMHRKTKLTNYLENLPTQRSTAVFSSCLRQNCSSDPNSLSLQRTPTLNQSRRMLYNEGNISSQAKSRLLKNTRQYSVDSSLFSKQVSSRKTPPFSRK
Sbjct:    1 MALNGKPKVLISLIVNNLSGTEGKLYWANISVETGGYIHSRDTIKTERKSGHDITFDAKLCIEYLFEEKQMIIIEIFEYDITQDGDNLLGEVDCSIGRVIHSGGVILKPLEITNEFKTTLGPLSPEVGIYVEEDLTAKENIELKIRGIGLAKTEIFGKTDPYLMIFRCNNRSRYVQCYRTEVLKNTQNPDWSPIVVSYERLCNNDLNSVLCLRVYCGDGTLKESEEVDIACDQLVGEIKVTARELIQMRRMEEKQFELINPKKKKKKKSYLNSGIISVRAQKTNSEPTFLDFMFQGLELNFIVAIDLTLSNGDSSLPSSLHFMDCSLTNEYSVAIQAVLEILQEYDNDELFPAFGFGARVPPDYKICHEYPLNGDFENPYCRGAEGVIHAYQQTLKEVKLAGPTCFSPVIRHISRLAKASESGKHYFVLLILTDGSVDDWVETKKAVVETSYLPVSIIVVGVGGGKFSDMETLDQDFGLLMVSNEKACRDNVQFVKMRRYLRVAADGSDNIRWSKVALAKDVLAELPYQVNEYMHRKTKLTNYLENLPTQRSTAVFSSCLRQNCSSDPNSLSLQRTPTLNQSRRMLYNEGNISSQAKSRLLKNTRQYSVDSSLFSKQVSSRKTPPFSRK 629          
BLAST of Copine-3 vs. Planmine SMEST
Match: SMESG000064685.1 (SMESG000064685.1)

HSP 1 Score: 1236.09 bits (3197), Expect = 0.000e+0
Identity = 615/618 (99.51%), Postives = 618/618 (100.00%), Query Frame = 1
Query:  193 MALNGKPKVLISLIVNNLSGTEGKLYWANISVETGGYIHSRDTIKTERKSGHDITFDAKLCIEYLFEEKQMIIIEIFEYDITQDGDNLLGEVDCSIGRVIHSGGVVLKPLEITDEFKTTLGPLSPEVGIYVEEDLTAKENIELKIRGIGLAKTEIFGKTDPYLMIFRCNNRSRYVQCYRTEVLKNTQNPDWSPIVVSYERLCNNDLNSVLCLRVYCGDGTLKESEEVDIACDQLVGEIKVTARELIQMRRMEEKQFELINPXXXXXXXSYLNSGIISVRAQKTNSEPTFLDFMFQGLELNFIVAIDLTLSNGDSSLPSSLHFMDCSLTNEYSVAIQAVLEILQEYDNDELFPAFGFGARVPPDYKICHEYPLNGDFENPYCRGAEGVIHAYQQTLKEVKLAGPTCFSPVIRHISRLAKASESGKHYFVLLILTDGSVDDWVETKKAVVETSYLPXXXXXXXXXXXKFSDMETLDQDFGLLMVSNEKACRDNVQFVKMRRYLRVAADGSDNIRWSKVALAKDVLAELPYQVNEYMHRKTKLTNYLENLPTQRSTAVFSSCLRQNCSSDPNSLSLQRTPTLNQSRRMLYNEGNISSQAKSRLLKNTRQYSVDSSLFSKQV 2046
            MALNGKPKVLISLIVNNLSGTEGKLYWANISVETGGYIHSRDTIKTERKSGHDITFDAKLCIEYLFEEKQMIIIEIFEYDITQDGDNLLGEVDCSIGRVIHSGGV+LKPLEIT+EFKTTLGPLSPEVGIYVEEDLTAKENIELKIRGIGLAKTEIFGKTDPYLMIFRCNNRSRYVQCYRTEVLKNTQNPDWSPIVVSYERLCNNDLNSVLCLRVYCGDGTLKESEEVDIACDQLVGEIKVTARELIQMRRMEEKQFELINPKKKKKKKSYLNSGIISVRAQKTNSEPTFLDFMFQGLELNFIVAIDLTLSNGDSSLPSSLHFMDCSLTNEYSVAIQAVLEILQEYDNDELFPAFGFGARVPPDYKICHEYPLNGDFENPYCRGAEGVIHAYQQTLKEVKLAGPTCFSPVIRHISRLAKASESGKHYFVLLILTDGSVDDWVETKKAVVETSYLPVSIIVVGVGGGKFSDMETLDQDFGLLMVSNEKACRDNVQFVKMRRYLRVAADGSDNIRWSKVALAKDVLAELPYQVNEYMHRKTKLTNYLENLPTQRSTAVFSSCLRQNCSSDPNSLSLQRTPTLNQSRRMLYNEGNISSQAKSRLLKNTRQYSVDSSLFSKQ+
Sbjct:    1 MALNGKPKVLISLIVNNLSGTEGKLYWANISVETGGYIHSRDTIKTERKSGHDITFDAKLCIEYLFEEKQMIIIEIFEYDITQDGDNLLGEVDCSIGRVIHSGGVILKPLEITNEFKTTLGPLSPEVGIYVEEDLTAKENIELKIRGIGLAKTEIFGKTDPYLMIFRCNNRSRYVQCYRTEVLKNTQNPDWSPIVVSYERLCNNDLNSVLCLRVYCGDGTLKESEEVDIACDQLVGEIKVTARELIQMRRMEEKQFELINPKKKKKKKSYLNSGIISVRAQKTNSEPTFLDFMFQGLELNFIVAIDLTLSNGDSSLPSSLHFMDCSLTNEYSVAIQAVLEILQEYDNDELFPAFGFGARVPPDYKICHEYPLNGDFENPYCRGAEGVIHAYQQTLKEVKLAGPTCFSPVIRHISRLAKASESGKHYFVLLILTDGSVDDWVETKKAVVETSYLPVSIIVVGVGGGKFSDMETLDQDFGLLMVSNEKACRDNVQFVKMRRYLRVAADGSDNIRWSKVALAKDVLAELPYQVNEYMHRKTKLTNYLENLPTQRSTAVFSSCLRQNCSSDPNSLSLQRTPTLNQSRRMLYNEGNISSQAKSRLLKNTRQYSVDSSLFSKQL 618          
BLAST of Copine-3 vs. Planmine SMEST
Match: SMESG000007275.1 (SMESG000007275.1)

HSP 1 Score: 582.022 bits (1499), Expect = 0.000e+0
Identity = 329/620 (53.06%), Postives = 430/620 (69.35%), Query Frame = 1
Query:  208 KPKVLISLIVNNLSGTEGKLYWANISVETGGYIHSRDTIKTER-KSGHDITFDAKLCIEYLFEEKQMIIIEIFEYDITQDGDNLLGEVDCSIGRVIHSGGVVLKPLEITDEFKTTLGPLSPEVGIYVEEDLTAKENIELKIRGIGLAKTEIFGKTDPYLMIFRCNNRSRYVQCYRTEVLKNTQNPDWSPIVVSYERLCNNDLNSVLCLRVYCGDGTLKESEEVDIACDQLVGEIKVTARELIQMRRMEEKQFELINPXXXXXXXSYLNSGIISVRAQKTNSEPTFLDFMFQGLELNFIVAIDLTLSNGDSSLPSSLHFMDCSLTNEYSVAIQAVLEILQEYDNDELFPAFGFGARVPPDYKICHEYPLNGDFENPYCRGAEGVIHAYQQTLKEVKLAGPTCFSPVIRHISRLAKASESGKHYFVLLILTDGSVDDWVETKKAVVETSYLPXXXXXXXXXXXKFSDMETLDQDFGLLMVSNEKACRDNVQFVKMRRYLRVAADGSDNIRWSKVALAKDVLAELPYQVNEYMHRKTKLTNYLENLPTQRSTAVFSSCLRQNCSSDPNSLSLQRTPTL---NQSRRMLYNEGNISSQAKSRLLKNTRQYSVDSSLFSKQVSSR 2055
            K KVLISL   NL     ++Y+A + V TGGY H +DTI TE+ K   DI F  KL +EY+FEEKQ+I IE+  + I       +  ++CS+GR+IHSGG + +  E    +K+    +  E+   V ED  +K+N+E+K++G GL K +IFGK+DPY++I+R N++ + ++ YR+EV+KNT NPDW  +V S ERLC NDL+  L  + +  DG   + E++D   D+L+GE   T R L+     E+K+FEL+N +KKKKKK+Y +SG+I++R  +T ++ +FLD+MF G +LNFIVAIDLT SNGD   P+SLH+MD + TNEYSVAIQAVLEILQEYDNDE+FPAFGFGARVPPD+KI HEYPLNGD+ NP+C+G EGV+ AY++ L +VKL+GPT F+PVIR +S L+K    G HYF+LLILTDGSVDDWVETK+AV+E SYLPVSIIV+GVGG KFSDME LDQDF LL V N++ACRDNVQFV MRR+LR AADGSD+IRW+KV+LAK+VLAELP QV  YM R          L  +RS       ++           L+R  T    +QS + +        +A S LLK  RQ SVD+SL      SR
Sbjct:    4 KSKVLISLSCRNLPTESFEMYYATLRVATGGYFHDKDTISTEKVKDSKDIDFIQKLQLEYIFEEKQIIRIEL--HGIYFGESACVATLECSVGRIIHSGGELSRFTEWC--WKSITCEI--EIIYKVTEDAASKDNLEIKMQGYGLDKKDIFGKSDPYVIIYRRNDKGKLIRTYRSEVVKNTLNPDWKAVVASLERLCGNDLDCELIFKCFDWDGANGDPEDMDTEFDELIGEFTTTTRYLLSANG-EQKKFELVNSRKKKKKKNYQHSGLITIRTIQTITDLSFLDYMFGGTDLNFIVAIDLTSSNGDVEDPTSLHYMDVNNTNEYSVAIQAVLEILQEYDNDEMFPAFGFGARVPPDFKISHEYPLNGDYSNPFCKGVEGVMKAYREALLQVKLSGPTHFAPVIRQVSNLSKEHRDGSHYFILLILTDGSVDDWVETKRAVIEASYLPVSIIVIGVGGRKFSDMEILDQDFKLLRVGNDQACRDNVQFVPMRRFLRAAADGSDSIRWNKVSLAKEVLAELPVQVLHYMSRHKGA------LGPRRSEHYRYCSMKDLLRQFSQDTRLRRCATSSYDDQSPKHMSQR-----RASSCLLKTGRQCSVDTSLQESDNKSR 605          
BLAST of Copine-3 vs. Planmine SMEST
Match: SMESG000029196.1 (SMESG000029196.1)

HSP 1 Score: 573.163 bits (1476), Expect = 0.000e+0
Identity = 319/621 (51.37%), Postives = 432/621 (69.57%), Query Frame = 1
Query:  208 KPKVLISLIVNNLSGTEGKLYWANISVETGGYIHSRDTIKTERKSGHDITFDAKLCIEYLFEEKQMIIIEIFEYDITQDGD-NLLGEVDCSIGRVIHSGGVVLKPLEITDEFKTTLG---PLSPEVGIYVEEDLTAKENIELKIRGIGLAKTEIFGKTDPYLMIFRCNNRSRYVQCYRTEVLKNTQNPDWSPIVVSYERLCNNDLNSVLCLRVYCGDGTLKESEEVDIACDQLVGEIKVTARELIQMRRMEEKQFELINPXXXXXXXSYLNSGIISVRAQKTNSEPTFLDFMFQGLELNFIVAIDLTLSNGDSSLPSSLHFMDCSLTNEYSVAIQAVLEILQEYDNDELFPAFGFGARVPPDYKICHEYPLNGDFENPYCRGAEGVIHAYQQTLKEVKLAGPTCFSPVIRHISRLAKASESGKHYFVLLILTDGSVDDWVETKKAVVETSYLPXXXXXXXXXXXKFSDMETLDQDFGLLMVSNEKACRDNVQFVKMRRYLRVAADGSDNIRWSKVALAKDVLAELPYQVNEYMHRKTKLTNYLENL-PTQRSTAVFSSCLRQN--CSSDPNSLSLQRTPT---LNQSRRMLYNEGNISSQAKSRLLKNTRQYSVDSSLFSK 2040
            KPKV++ +   NL  T    Y+A  SV TGGYIH +D +KTE ++  +  F  +L ++Y FEEKQ I +EIF   +++D   + +G  + +IGRVIHSGG +   L+I  +   + G     SP    YV ED   KENIE+K++G  L K ++FGK+DPY+++++ N R + V+ YR+E++KNT NPDW  I+VS E+LCN +L S + ++ +  DG   + E++D   D+++GE  + A+E +    ++E++FELIN +KKKKKK Y NSGI++VR  + + + +F+D+MF G +LNFIVAIDLT SNGD   PSSLHF+D + +NEYS+AIQAVLEILQEYDNDELFPAFGFGARV PD+KICHEYPL GDF NP+C G EGVI+AY + L+ +KL+GPT F+PVIR +  LAK    G HYFVLLILTDG+VDDW+ETKKAV+E S+LP+SIIVVGVGGGKF DM+TLDQDFGLL V NE+ACRDNVQFV MR++LR AADGSDN++WSKVALAK+VLAELP Q+ +YM++         NL P   + ++ S+ L  +   + +     L+R  T   + +S R    +G        R  + TR+ SVDS    +
Sbjct:    3 KPKVIVGIGCLNLPDTFLS-YYAEFSVATGGYIHDKDVMKTENQTDQNPIFKCQLNLDYFFEEKQCIKVEIF--GLSKDSKISKIGCAESTIGRVIHSGGELF--LQINIDKDLSYGNNESHSPICIFYVREDSDCKENIEIKMQGFNLDKKDLFGKSDPYVIMYKKNERGKLVKTYRSEIIKNTLNPDWRSIMVSVEKLCNKNLQSEIYVKCFDWDGAKGDPEDMDNEFDEIIGEFSIPAKEFL-YPYIQERKFELINSRKKKKKKGYSNSGIVTVRTNQVSKDNSFIDYMFGGTDLNFIVAIDLTSSNGDIHDPSSLHFIDENSSNEYSIAIQAVLEILQEYDNDELFPAFGFGARVAPDFKICHEYPLTGDFSNPFCHGVEGVINAYHEVLQNIKLSGPTYFAPVIRQVINLAKQYCDGSHYFVLLILTDGTVDDWIETKKAVIEASFLPISIIVVGVGGGKFLDMKTLDQDFGLLKVGNEQACRDNVQFVPMRKFLRPAADGSDNVKWSKVALAKEVLAELPEQLLDYMNK--------HNLKPIGENKSLLSATLDNSKLNAKEFVQQKLRRCATAYGMTKSNRQGSTDG-----LNGRGFRGTRKCSVDSQFLEE 604          
The following BLAST results are available for this feature:
BLAST of Copine-3 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
CPNE86.301e-10039.59copine 8 [Source:HGNC Symbol;Acc:HGNC:23498][more]
CPNE81.075e-9939.59copine 8 [Source:HGNC Symbol;Acc:HGNC:23498][more]
CPNE56.331e-9738.43copine 5 [Source:HGNC Symbol;Acc:HGNC:2318][more]
CPNE91.483e-9638.85copine family member 9 [Source:HGNC Symbol;Acc:HGN... [more]
CPNE21.793e-9538.08copine 2 [Source:HGNC Symbol;Acc:HGNC:2315][more]
back to top
BLAST of Copine-3 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
gem-46.796e-7133.92Gon-2 Extragenic Modifier [Source:UniProtKB/TrEMB... [more]
gem-46.796e-7133.92Gon-2 Extragenic Modifier [Source:UniProtKB/TrEMB... [more]
nra-16.616e-6633.67Nicotinic receptor-associated protein 1 [Source:U... [more]
nra-14.534e-6533.67Nicotinic receptor-associated protein 1 [Source:U... [more]
cpna-56.740e-3527.56Copine family protein 5 [Source:UniProtKB/Swiss-P... [more]
back to top
BLAST of Copine-3 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 0
Match NameE-valueIdentityDescription
back to top
BLAST of Copine-3 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
cpne5b2.254e-10439.51copine Vb [Source:ZFIN;Acc:ZDB-GENE-040426-1398][more]
cpne5b2.812e-10339.15copine Vb [Source:ZFIN;Acc:ZDB-GENE-040426-1398][more]
cpne5a1.240e-10239.43copine Va [Source:ZFIN;Acc:ZDB-GENE-081105-9][more]
cpne82.246e-10140.00copine VIII [Source:ZFIN;Acc:ZDB-GENE-100809-1][more]
cpne13.366e-9737.33copine I [Source:ZFIN;Acc:ZDB-GENE-030131-3562][more]
back to top
BLAST of Copine-3 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
acot111.598e-10241.39acyl-CoA thioesterase 11 [Source:Xenbase;Acc:XB-GE... [more]
acot112.250e-9940.95acyl-CoA thioesterase 11 [Source:Xenbase;Acc:XB-GE... [more]
cpne93.325e-9938.20copine family member IX [Source:NCBI gene;Acc:1001... [more]
acot111.717e-9840.99acyl-CoA thioesterase 11 [Source:Xenbase;Acc:XB-GE... [more]
cpne92.234e-9838.25copine family member IX [Source:NCBI gene;Acc:1001... [more]
back to top
BLAST of Copine-3 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Cpne89.338e-10039.59copine VIII [Source:MGI Symbol;Acc:MGI:1914121][more]
Cpne52.149e-9838.83copine V [Source:MGI Symbol;Acc:MGI:2385908][more]
Cpne97.338e-9739.22copine family member IX [Source:MGI Symbol;Acc:MGI... [more]
Cpne22.334e-9137.78copine II [Source:MGI Symbol;Acc:MGI:2387578][more]
Cpne23.358e-9137.90copine II [Source:MGI Symbol;Acc:MGI:2387578][more]
back to top
BLAST of Copine-3 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q86YQ8|CPNE8_HUMAN3.026e-9939.59Copine-8 OS=Homo sapiens OX=9606 GN=CPNE8 PE=1 SV=... [more]
sp|Q9DC53|CPNE8_MOUSE6.532e-9939.59Copine-8 OS=Mus musculus OX=10090 GN=Cpne8 PE=2 SV... [more]
sp|Q8JZW4|CPNE5_MOUSE1.504e-9738.83Copine-5 OS=Mus musculus OX=10090 GN=Cpne5 PE=1 SV... [more]
sp|Q9HCH3|CPNE5_HUMAN3.040e-9638.43Copine-5 OS=Homo sapiens OX=9606 GN=CPNE5 PE=1 SV=... [more]
sp|Q1RLL3|CPNE9_MOUSE4.618e-9639.22Copine-9 OS=Mus musculus OX=10090 GN=Cpne9 PE=1 SV... [more]
back to top
BLAST of Copine-3 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A267G9Y02.120e-16549.91Uncharacterized protein (Fragment) OS=Macrostomum ... [more]
A0A267FGY63.381e-16449.53Uncharacterized protein (Fragment) OS=Macrostomum ... [more]
A0A4S2L3S03.847e-16249.35C2 domain-containing protein OS=Opisthorchis felin... [more]
A0A267ER931.550e-15748.03Uncharacterized protein OS=Macrostomum lignano OX=... [more]
A0A267EIM62.839e-15748.03Uncharacterized protein OS=Macrostomum lignano OX=... [more]
back to top
BLAST of Copine-3 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
cpne5b4.101e-10339.51copine-5 [Source:NCBI gene;Acc:103046149][more]
cpne5b9.791e-10339.10copine-5 [Source:NCBI gene;Acc:103046149][more]
CPNE89.539e-10139.96copine 8 [Source:HGNC Symbol;Acc:HGNC:23498][more]
cpne11.393e-9837.72copine-3-like [Source:NCBI gene;Acc:103034615][more]
cpne12.000e-9838.32copine-3-like [Source:NCBI gene;Acc:103034615][more]
back to top
BLAST of Copine-3 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
cpne24.475e-9139.76copine II [Source:ZFIN;Acc:ZDB-GENE-030131-7896][more]
ENSPMAT00000007777.15.341e-7535.61pep scaffold:Pmarinus_7.0:GL477373:3581:22444:1 ge... [more]
ENSPMAT00000000748.16.066e-6237.05pep scaffold:Pmarinus_7.0:GL477446:179420:193439:1... [more]
cpne23.675e-5546.64copine II [Source:ZFIN;Acc:ZDB-GENE-030131-7896][more]
cpne22.694e-1832.34copine II [Source:ZFIN;Acc:ZDB-GENE-030131-7896][more]
back to top
BLAST of Copine-3 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
back to top
BLAST of Copine-3 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO443522.054e-9942.24Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO395007.850e-9437.60Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO459271.047e-8437.35Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO499021.464e-4130.75Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO268012.515e-3040.72Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
back to top
BLAST of Copine-3 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
cpne5a7.881e-10439.75copine-5 [Source:NCBI gene;Acc:101166794][more]
cpne5a9.864e-10439.43copine-5 [Source:NCBI gene;Acc:101166794][more]
cpne5b2.737e-10339.51copine-8 [Source:NCBI gene;Acc:101170754][more]
CPNE82.139e-10240.37copine 8 [Source:NCBI gene;Acc:101158741][more]
cpne5b2.838e-10239.51copine-8 [Source:NCBI gene;Acc:101170754][more]
back to top
BLAST of Copine-3 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000064685.10.000e+099.68SMESG000064685.1[more]
SMESG000064685.10.000e+099.68SMESG000064685.1[more]
SMESG000064685.10.000e+099.51SMESG000064685.1[more]
SMESG000007275.10.000e+053.06SMESG000007275.1[more]
SMESG000029196.10.000e+051.37SMESG000029196.1[more]
back to top
Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30009900 ID=SMED30009900|Name=Copine-3|organism=Schmidtea mediterranea sexual|type=transcript|length=2163bp
ATTTTTTTCCATGTGACAGTTGAATTTTACTGGTGAAAAATAATATTGTT
TAATTTTATTTCGTTGCCATTCGTTACCAACAACACCAATCAACATCGTT
AAACTGGAATCAATTTTATAGATGAAATTTCTAATTGATAAAATATTACA
ACTAATTTTATTATTAATATTGTCAGAAACTTTTCCCAAAAAATGGCTTT
AAATGGAAAGCCAAAAGTTCTCATTAGTCTCATTGTAAATAATCTCAGTG
GGACTGAAGGCAAGTTATACTGGGCTAATATCAGCGTTGAAACTGGAGGT
TATATTCACAGTCGAGATACAATAAAAACGGAAAGGAAAAGTGGCCACGA
TATTACTTTTGATGCAAAACTTTGTATTGAATATCTTTTTGAAGAAAAGC
AAATGATTATAATAGAAATATTTGAATACGATATCACTCAGGATGGAGAT
AATTTACTGGGTGAAGTGGACTGTTCAATTGGCAGAGTTATTCACAGCGG
AGGAGTCGTATTGAAACCATTAGAAATAACTGATGAATTCAAAACGACTT
TGGGACCGCTTTCTCCGGAAGTTGGAATTTATGTGGAAGAAGATCTCACT
GCAAAGGAAAACATCGAATTGAAAATACGAGGAATTGGATTAGCCAAAAC
AGAAATATTCGGTAAAACTGATCCGTATTTAATGATATTCAGATGCAACA
ATCGTAGCAGATATGTGCAATGTTATCGAACAGAGGTCCTCAAAAATACA
CAGAATCCAGACTGGTCTCCAATCGTTGTGTCATATGAGCGATTATGTAA
CAATGACCTTAACAGCGTTCTTTGTTTGAGAGTTTATTGTGGAGATGGGA
CATTAAAAGAGTCAGAAGAAGTCGATATAGCGTGCGATCAGTTGGTTGGA
GAAATTAAAGTAACAGCAAGAGAGTTGATACAGATGCGAAGAATGGAAGA
AAAACAATTTGAACTGATCAATCCAAAGAAAAAGAAAAAGAAAAAATCAT
ATCTAAATTCTGGAATAATTAGTGTGCGAGCTCAAAAAACAAATTCAGAG
CCAACATTTCTTGATTTCATGTTTCAAGGACTCGAACTAAATTTTATAGT
TGCAATTGACCTAACATTATCAAATGGAGATTCCAGTTTGCCCTCGTCCC
TTCATTTCATGGACTGCTCACTGACAAATGAATATTCGGTTGCTATTCAA
GCCGTGTTAGAGATATTGCAAGAATATGATAATGATGAACTGTTTCCGGC
ATTTGGGTTTGGAGCTAGAGTACCACCGGACTATAAAATATGTCACGAAT
ATCCTTTGAATGGAGATTTTGAAAATCCGTATTGTCGAGGAGCTGAGGGC
GTCATCCATGCATATCAGCAGACATTAAAGGAGGTAAAACTAGCTGGGCC
GACTTGTTTTTCACCAGTTATTAGGCATATTTCAAGATTAGCGAAAGCTT
CAGAAAGTGGGAAGCATTATTTTGTATTGTTAATTCTTACTGATGGCTCA
GTTGATGATTGGGTTGAGACTAAAAAAGCTGTTGTTGAAACGTCTTATTT
GCCAGTGTCAATCATTGTTGTTGGGGTCGGTGGTGGAAAGTTTTCTGATA
TGGAAACTTTAGATCAGGATTTCGGTTTGCTTATGGTCAGTAATGAAAAG
GCTTGCCGAGACAATGTGCAATTTGTAAAAATGCGTCGATATTTGCGTGT
TGCTGCTGATGGATCAGACAATATTCGTTGGTCTAAAGTCGCCTTGGCTA
AAGACGTTTTAGCAGAATTACCATATCAAGTAAATGAATATATGCATCGT
AAAACTAAACTTACAAATTACCTCGAAAATCTTCCCACTCAACGTTCGAC
TGCTGTTTTCAGTAGTTGCCTACGTCAAAACTGCTCCTCAGACCCGAACA
GTTTGAGTCTTCAACGTACACCAACATTAAATCAATCTAGACGTATGTTG
TACAACGAAGGCAATATCAGTTCACAAGCGAAATCGAGATTACTGAAAAA
CACCAGACAATATTCTGTTGATTCCTCTTTATTTTCTAAACAGGTTTCCA
GTCGTAAAACACCCCCATTCTCAAGAAAGTCTAATTTCTCATGATTTCTT
AATGCCTTCGGTAAAATAGTTTATGTTTCAAGTTTGTACAATACAAACAT
TGAGTGTCTTTTG
back to top

protein sequence of SMED30009900-orf-1

>SMED30009900-orf-1 ID=SMED30009900-orf-1|Name=SMED30009900-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=634bp
MALNGKPKVLISLIVNNLSGTEGKLYWANISVETGGYIHSRDTIKTERKS
GHDITFDAKLCIEYLFEEKQMIIIEIFEYDITQDGDNLLGEVDCSIGRVI
HSGGVVLKPLEITDEFKTTLGPLSPEVGIYVEEDLTAKENIELKIRGIGL
AKTEIFGKTDPYLMIFRCNNRSRYVQCYRTEVLKNTQNPDWSPIVVSYER
LCNNDLNSVLCLRVYCGDGTLKESEEVDIACDQLVGEIKVTARELIQMRR
MEEKQFELINPKKKKKKKSYLNSGIISVRAQKTNSEPTFLDFMFQGLELN
FIVAIDLTLSNGDSSLPSSLHFMDCSLTNEYSVAIQAVLEILQEYDNDEL
FPAFGFGARVPPDYKICHEYPLNGDFENPYCRGAEGVIHAYQQTLKEVKL
AGPTCFSPVIRHISRLAKASESGKHYFVLLILTDGSVDDWVETKKAVVET
SYLPVSIIVVGVGGGKFSDMETLDQDFGLLMVSNEKACRDNVQFVKMRRY
LRVAADGSDNIRWSKVALAKDVLAELPYQVNEYMHRKTKLTNYLENLPTQ
RSTAVFSSCLRQNCSSDPNSLSLQRTPTLNQSRRMLYNEGNISSQAKSRL
LKNTRQYSVDSSLFSKQVSSRKTPPFSRKSNFS*
back to top
Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: molecular function
TermDefinition
GO:0005544calcium-dependent phospholipid binding
GO:0048306calcium-dependent protein binding
GO:0005515protein binding
GO:0003674molecular_function
Vocabulary: cellular component
TermDefinition
GO:0005634nucleus
GO:0005737cytoplasm
GO:0005886plasma membrane
GO:0005925focal adhesion
GO:0016020membrane
GO:0030054cell junction
GO:0070062extracellular exosome
Vocabulary: biological process
TermDefinition
GO:0030335positive regulation of cell migration
GO:0038128ERBB2 signaling pathway
GO:0071277cellular response to calcium ion
GO:0071363cellular response to growth factor stimulus
GO:0008150biological_process
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000099neuron
PLANA:0000418head
PLANA:0002089reproductive organ
Vocabulary: INTERPRO
TermDefinition
IPR035892C2_domain_sf
IPR037768C2B_Copine
IPR036465vWFA_dom_sf
IPR000008C2_dom
IPR010734Copine
IPR002035VWF_A
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR000008C2 domainPFAMPF00168C2coord: 43..104
e-value: 0.42
score: 10.9
coord: 146..256
e-value: 5.1E-5
score: 23.5
IPR035892C2 domain superfamilyGENE3DG3DSA:2.60.40.150coord: 144..288
e-value: 2.8E-12
score: 48.9
IPR010734CopinePFAMPF07002Copinecoord: 319..537
e-value: 7.6E-69
score: 231.5
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 613..633
NoneNo IPR availablePANTHERPTHR10857COPINEcoord: 52..538
NoneNo IPR availableSUPERFAMILYSSF49562C2 domain (Calcium/lipid-binding domain, CaLB)coord: 145..271
IPR037768Copine, C2B domainCDDcd04047C2B_Copinecoord: 139..260
e-value: 1.66024E-27
score: 104.955
IPR036465von Willebrand factor A-like domain superfamilySUPERFAMILYSSF53300vWA-likecoord: 298..487