Macrophage erythroblast attacher

Overview
NameMacrophage erythroblast attacher
Smed IDSMED30009887
Length (bp)1477
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Macrophage erythroblast attacher (SMED30009887) t-SNE clustered cells

Violin plots show distribution of expression levels for Macrophage erythroblast attacher (SMED30009887) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Macrophage erythroblast attacher (SMED30009887) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Macrophage erythroblast attacher (SMED30009887) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30009887

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 7

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
pharynxSMED30009887SMESG000048410.1 dd_Smed_v4_1168_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
nervous systemSMED30009887SMESG000048410.1 dd_Smed_v4_1168_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30009887SMESG000048410.1 dd_Smed_v4_1168_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30009887SMESG000048410.1 dd_Smed_v4_1168_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30009887SMESG000048410.1 Contig47924uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30009887SMESG000048410.1 Contig47924newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
epidermisSMED30009887SMESG000048410.1 dd_Smed_v4_1168_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017		whole organism asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Macrophage erythroblast attacher vs. Ensembl Human
Match: MAEA (macrophage erythroblast attacher [Source:HGNC Symbol;Acc:HGNC:13731])

HSP 1 Score: 117.472 bits (293), Expect = 3.502e-28
Identity = 108/412 (26.21%), Postives = 186/412 (45.15%), Query Frame = 1 
Query:   85 VKLTELTTLKASYEYLNKAYRGNQKSLEKDYQSMVKSIEDYKKANDAENAQNCIGLFLENV----SNLKRKAETIIAEELNYTKTCKIRLDHLLNLSVSKGNGNNQNCXXXXXXXXXXXXXXXXXSFLYEKGDNMQLKRMDNIDSTVRFQRHLADHLFAQGYCNTAVELAKSINIGENLEDNIGMIEIYQETLDIVEALKKGNFYPVEQWLQSIQFKYKKGDVKNSFESDLQIFKLYLLIKEGNWEKAIKFAHSFCDPKMINEDTMEKLSKVMTLVVF------RSYDELVAAARKWDVDEDWIVQRFHSFILQFYAFYHEPTVLSLMIKTGIAVRKTENCYKPN--MKRKECVVCTDRVNKISVDIPAARHDHSILVCWKTSLEMNEDNPPVAFPNGYVYSTKVWQEIRNN 1284
            +K+ E  TLK  YE LNK +R  QK+++++   +   + + +K      A + +   L+ V    S LKRKA   I  E    K CK R++HL      K + ++Q                             + KRMD         R + +HL   GY NTAV+LA+   I    ED +  IE++    ++ E+L++        W    + + +K  +K+  E  L+I +   LI++     A++ A             ++++ + M ++ F        Y +L+  AR W +    ++Q+F     + +   +  +V +L ++ G++  KT  CYK +   K  +C VC+  +NK++  +P A   +S LVC  +   MNE+NPP+  PNGYVY       IR +
Sbjct:   14 LKVQEYPTLKVPYETLNKRFRAAQKNIDRETSHVTMVVAELEKTLSGCPAVDSVVSLLDGVVEKLSVLKRKAVESIQAEDESAKLCKRRIEHL------KEHSSDQPAA----------------------ASVWKRKRMD---------RMMVEHLLRCGYYNTAVKLARQSGI----EDLVN-IEMFLTAKEVEESLERRETATCLAWCHDNKSRLRK--MKSCLEFSLRIQEFIELIRQNKRLDAVRHARKHFS--QAEGSQLDEVRQAMGMLAFPPDTHISPYKDLLDPAR-WRM----LIQQFRYDNYRLHQLGNN-SVFTLTLQAGLSAIKTPQCYKEDGSSKSPDCPVCSRSLNKLAQPLPMAHCANSRLVCKISGDVMNENNPPMMLPNGYVYGYNSLLSIRQD 373
[Close]
BLAST of Macrophage erythroblast attacher vs. Ensembl Human
Match: MAEA (macrophage erythroblast attacher [Source:HGNC Symbol;Acc:HGNC:13731])

HSP 1 Score: 111.694 bits (278), Expect = 2.850e-26
Identity = 108/419 (25.78%), Postives = 191/419 (45.58%), Query Frame = 1 
Query:   64 NSDCQDEVKLTELTTLKASYEYLNKAYRGNQKSLEKDYQSMVKSIEDYKKANDAENAQNCIGLFLENV----SNLKRKAETIIAEELNYTKTCKIRLDHLLNLSVSKGNGNNQNCXXXXXXXXXXXXXXXXXSFLYEKGDNMQLKRMDNIDSTVRFQRHLADHLFAQGYCNTAVELAKSINIGENLEDNIGMIEIYQETLDIVEALKKGNFYPVEQWLQSIQFKYKKGDVKNSFESDLQIFKLYLLIKEGNWEKAIKFAHSFCDPKMINEDTMEKLSKVMTLVVF------RSYDELVAAARKWDVDEDWIVQRFHSFILQFYAFYHEPTVLSLMIKTGIAVRKTENCYKPN--MKRKECVVCTDRVNKISVDIPAARHDHSILVCWKTSLEMNEDNPPVAFPNGYVYSTKVWQEIRNN 1284
            +S C+D       T     YE LNK +R  QK+++++   +   + + +K      A + +   L+ V    S LKRKA   I  E    K CK R++HL      K + ++Q                P ++ ++++      KRMD         R + +HL   GY NTAV+LA+   I    ED +  IE++    ++ E+L++        W    + + +K  +K+  E  L+I +   LI++     A++ A             ++++ + M ++ F        Y +L+  AR W +    ++Q+F     + +   +  +V +L ++ G++  KT  CYK +   K  +C VC+  +NK++  +P A   +S LVC  +   MNE+NPP+  PNGYVY       IR +
Sbjct:   13 SSSCED-------TVAPVPYETLNKRFRAAQKNIDRETSHVTMVVAELEKTLSGCPAVDSVVSLLDGVVEKLSVLKRKAVESIQAEDESAKLCKRRIEHL------KEHSSDQ----------------PAAASVWKR------KRMD---------RMMVEHLLRCGYYNTAVKLARQSGI----EDLVN-IEMFLTAKEVEESLERRETATCLAWCHDNKSRLRK--MKSCLEFSLRIQEFIELIRQNKRLDAVRHARKHFS--QAEGSQLDEVRQAMGMLAFPPDTHISPYKDLLDPAR-WRM----LIQQFRYDNYRLHQLGNN-SVFTLTLQAGLSAIKTPQCYKEDGSSKSPDCPVCSRSLNKLAQPLPMAHCANSRLVCKISGDVMNENNPPMMLPNGYVYGYNSLLSIRQD 372
[Close]
BLAST of Macrophage erythroblast attacher vs. Ensembl Human
Match: MAEA (macrophage erythroblast attacher [Source:HGNC Symbol;Acc:HGNC:13731])

HSP 1 Score: 103.605 bits (257), Expect = 2.897e-23
Identity = 109/448 (24.33%), Postives = 187/448 (41.74%), Query Frame = 1 
Query:   85 VKLTELTTLKASYEYLNKAYRGNQKSLEKDYQSMVKSIEDYKKANDAENAQNCIGLFLENV----SNLKRKAETIIAEELNYTKTCKIRLDHLLNLSVSKGNGNNQNCXXXXXXXXXXXXXXXXXSFLYEKGDNMQLKRMDNIDSTVRFQRHLADHLFAQGYCNTAVELAKSINIGENLEDNIGMIEIYQETLDIVEALKKGNFYPVEQW-------LQSIQFKYKKGDVKNS-----------------------------FESDLQIFKLYLLIKEGNWEKAIKFAHSFCDPKMINEDTMEKLSKVMTLVVF------RSYDELVAAARKWDVDEDWIVQRFHSFILQFYAFYHEPTVLSLMIKTGIAVRKTENCYKPN--MKRKECVVCTDRVNKISVDIPAARHDHSILVCWKTSLEMNEDNPPVAFPNGYVYSTKVWQEIRNN 1284
            +K+ E  TLK  YE LNK +R  QK+++++   +   + + +K      A + +   L+ V    S LKRKA   I  E    K CK R++HL      K + ++Q                             + KRMD         R + +HL   GY NTAV+LA+   I    ED +  IE++    ++ E+L++        W       L+ ++ +  K + K                                E  L+I +   LI++     A++ A             ++++ + M ++ F        Y +L+  AR W +    ++Q+F     + +   +  +V +L ++ G++  KT  CYK +   K  +C VC+  +NK++  +P A   +S LVC  +   MNE+NPP+  PNGYVY       IR +
Sbjct:   14 LKVQEYPTLKVPYETLNKRFRAAQKNIDRETSHVTMVVAELEKTLSGCPAVDSVVSLLDGVVEKLSVLKRKAVESIQAEDESAKLCKRRIEHL------KEHSSDQPAAASV----------------------WKRKRMD---------RMMVEHLLRCGYYNTAVKLARQSGI----EDLVN-IEMFLTAKEVEESLERRETATCLAWCHDNKSRLRKMKGRQNKHEAKTGRKSRAASSSPKESLDLGMETLKGKPELSCLEFSLRIQEFIELIRQNKRLDAVRHARKHFS--QAEGSQLDEVRQAMGMLAFPPDTHISPYKDLLDPAR-WRM----LIQQFRYDNYRLHQLGNN-SVFTLTLQAGLSAIKTPQCYKEDGSSKSPDCPVCSRSLNKLAQPLPMAHCANSRLVCKISGDVMNENNPPMMLPNGYVYGYNSLLSIRQD 411
[Close]
BLAST of Macrophage erythroblast attacher vs. Ensembl Human
Match: MAEA (macrophage erythroblast attacher [Source:HGNC Symbol;Acc:HGNC:13731])

HSP 1 Score: 97.8265 bits (242), Expect = 9.546e-22
Identity = 93/351 (26.50%), Postives = 163/351 (46.44%), Query Frame = 1 
Query:  256 LENVSNLKRKAETIIAEELNYTKTCKIRLDHLLNLSVSKGNGNNQNCXXXXXXXXXXXXXXXXXSFLYEKGDNMQLKRMDNIDSTVRFQRHLADHLFAQGYCNTAVELAKSINIGENLEDNIGMIEIYQETLDIVEALKKGNFYPVEQWLQSIQFKYKKGDVKNSFESDLQIFKLYLLIKEGNWEKAIKFAHSFCDPKMINEDTMEKLSKVMTLVVF------RSYDELVAAARKWDVDEDWIVQRFHSFILQFYAFYHEPTVLSLMIKTGIAVRKTENCYKPN--MKRKECVVCTDRVNKISVDIPAARHDHSILVCWKTSLEMNEDNPPVAFPNGYVYSTKVWQEIRNN 1284
            +E +S LKRKA   I  E    K CK R++HL      K + ++Q                P ++ ++++      KRMD         R + +HL   GY NTAV+LA+   I    ED +  IE++    ++ E+L++        W    + + +K  +K+  E  L+I +   LI++     A++ A             ++++ + M ++ F        Y +L+  AR W +    ++Q+F     + +   +  +V +L ++ G++  KT  CYK +   K  +C VC+  +NK++  +P A   +S LVC  +   MNE+NPP+  PNGYVY       IR +
Sbjct:   27 VEKLSVLKRKAVESIQAEDESAKLCKRRIEHL------KEHSSDQ----------------PAAASVWKR------KRMD---------RMMVEHLLRCGYYNTAVKLARQSGI----EDLVN-IEMFLTAKEVEESLERRETATCLAWCHDNKSRLRK--MKSCLEFSLRIQEFIELIRQNKRLDAVRHARKHFS--QAEGSQLDEVRQAMGMLAFPPDTHISPYKDLLDPAR-WRM----LIQQFRYDNYRLHQLGNN-SVFTLTLQAGLSAIKTPQCYKEDGSSKSPDCPVCSRSLNKLAQPLPMAHCANSRLVCKISGDVMNENNPPMMLPNGYVYGYNSLLSIRQD 325
[Close]
BLAST of Macrophage erythroblast attacher vs. Ensembl Human
Match: MAEA (macrophage erythroblast attacher [Source:HGNC Symbol;Acc:HGNC:13731])

HSP 1 Score: 96.2857 bits (238), Expect = 3.313e-21
Identity = 98/412 (23.79%), Postives = 167/412 (40.53%), Query Frame = 1 
Query:   85 VKLTELTTLKASYEYLNKAYRGNQKSLEKDYQSMVKSIEDYKKANDAENAQNCIGLFLENV----SNLKRKAETIIAEELNYTKTCKIRLDHLLNLSVSKGNGNNQNCXXXXXXXXXXXXXXXXXSFLYEKGDNMQLKRMDNIDSTVRFQRHLADHLFAQGYCNTAVELAKSINIGENLEDNIGMIEIYQETLDIVEALKKGNFYPVEQWLQSIQFKYKKGDVKNSFESDLQIFKLYLLIKEGNWEKAIKFAHSFCDPKMINEDTMEKLSKVMTLVVF------RSYDELVAAARKWDVDEDWIVQRFHSFILQFYAFYHEPTVLSLMIKTGIAVRKTENCYKPN--MKRKECVVCTDRVNKISVDIPAARHDHSILVCWKTSLEMNEDNPPVAFPNGYVYSTKVWQEIRNN 1284
            +K+ E  TLK  YE LNK +R  QK+++++   +   + + +K      A + +   L+ V    S LKRKA   I  E    K CK R++HL      K + ++Q                             + KRMD         R + +HL   GY NTAV+LA+                                                +  +++  E  L+I +   LI++     A++ A             ++++ + M ++ F        Y +L+  AR W +    ++Q+F     + +   +  +V +L ++ G++  KT  CYK +   K  +C VC+  +NK++  +P A   +S LVC  +   MNE+NPP+  PNGYVY       IR +
Sbjct:   14 LKVQEYPTLKVPYETLNKRFRAAQKNIDRETSHVTMVVAELEKTLSGCPAVDSVVSLLDGVVEKLSVLKRKAVESIQAEDESAKLCKRRIEHL------KEHSSDQPAAASV----------------------WKRKRMD---------RMMVEHLLRCGYYNTAVKLAR------------------------------------------------QSGIESCLEFSLRIQEFIELIRQNKRLDAVRHARKHFS--QAEGSQLDEVRQAMGMLAFPPDTHISPYKDLLDPAR-WRM----LIQQFRYDNYRLHQLGNN-SVFTLTLQAGLSAIKTPQCYKEDGSSKSPDCPVCSRSLNKLAQPLPMAHCANSRLVCKISGDVMNENNPPMMLPNGYVYGYNSLLSIRQD 332
[Close]
BLAST of Macrophage erythroblast attacher vs. Ensembl Celegans
Match: maea-1 (MAEA (MAcrophage Erythroblast Attacher protein) homolog [Source:UniProtKB/TrEMBL;Acc:O18188])

HSP 1 Score: 70.4774 bits (171), Expect = 7.079e-13
Identity = 87/410 (21.22%), Postives = 166/410 (40.49%), Query Frame = 1 
Query:  106 TLKASYEYLNKAYRGNQKSLEKDYQSMVKSIEDYKKANDA-------ENAQNCIGLFLENVSNLKRKAETIIAEELNYTKTCKIRLDHLLN-LSVSKGNGNNQNCXXXXXXXXXXXXXXXXXSFLYEKGDNMQLKRMDNIDSTVRFQRHLADHLFAQGYCNTAVELAKSINIGENLEDNIGMIEIYQETLDIVEALKKGNFYPVEQWLQSIQFKYKKGDVKNSFESDLQIFKLYLLIKEGNWEKAIKFAHSFCDPKMINEDTMEKLSKVM-----TLVVFRSYDELVAAARKWDVDEDWIVQRFHSFILQFYAFYHEPTVLSLMIKTGIAVRKTENCY---KPNMKRKECVVCTDRVNKISVDIPAARHDHSILVCWKTSLEMNED-NPPVAFPNGYVYSTKVWQEIRNN 1284
            T +  YE LN  +R  QK L++    + K+ E  +K           E+ +    L +  V   ++  E I   E+        R D +     V++ + N +N +                          +L+R        +F R +  H+   GY   A  L K + + E+L D    +++++    + +AL  GN  P   W      K +K + +    +  Q  +   LI+ GN  +A+ +   +  P    + T E L K M     TL   R  +  + AA ++       ++  H          H  T L+ +I+ G+A +KT +C+   K  + +++C+VC   V  I+ ++P +   +S + C  +    ++D N P  FP+G+V  +   + ++ +
Sbjct:   41 TFRIPYEELNIRFRNGQKDLDRAATGVAKAAELLQKKTAGSNEPVSRESLRRHFDLLIRQVQEARKTVERITQSEIEQLDKITTRADRIHEEFEVTRDSENPRNTE--------------------------KLERQ-------KFCRFIVWHMLRCGYIEPAKVLVKEMEL-EDLVD----VDVFENMYAVQQALLDGNIQPCLAWCDRHHRKLRKLESRIELVARQQ--EAVTLIELGNIPEAVAYVKKYIAPIAKGKFT-EDLKKTMGAIACTLEQSRLRNPELHAADRYQKCAALFIEEAHRIF-----EIHGNTALATLIQYGLATQKTPSCHNDEKTPLDKQKCIVCRPDVWPIAENLPYSHVANSRIFCSLSGKLCDDDKNIPFLFPSGHVIGSAAIERLKRD 404
[Close]
BLAST of Macrophage erythroblast attacher vs. Ensembl Fly
Match: CG31357 (gene:FBgn0051357 transcript:FBtr0084735)

HSP 1 Score: 116.316 bits (290), Expect = 3.342e-28
Identity = 103/425 (24.24%), Postives = 191/425 (44.94%), Query Frame = 1 
Query:   82 EVKLTELTTLKASYEYLNKAYRGNQKSLEKDYQSMVKSIEDYKKANDAENAQNC--IGLFLENVSN----LKRKAETIIAEELNYTKTCKIRLDHLLNLSVSKGNGNNQNCXXXXXXXXXXXXXXXXXSFLYEKGDNMQLKRMDNIDSTVRFQRHLADHLFAQGYCNTAVELAKSINIGENLEDNIGMIEIYQETLDIVEALKKGNFYPVEQWLQSIQFKYKKGDVKNSFESDLQIFKLYLLIKEGNWEKAIKFAHSFCDPKMINEDTMEKLSKVMTLVVFRSYDELVAAARKWDVDEDWIVQRFHSFILQF----YAFYH--EPTVLSLMIKTGIAVRKTENCYKPNMKRKECVVCTDRVNKISVDIPAARHDHSILVCWKTSLEMNEDNPPVAFPNGYVYSTKVWQEIRNNSVTFALIISHCR 1320
            E+K  E  TLK  YE LNK +R  QK ++++   ++      +KA +AE       +   ++NV+     LKRKAE  I +EL+ T+ CK +LDHL  ++       +                      L++ G   Q KR       +R  R + +HL   GY  TA ELA   ++      ++  ++I+Q + ++ + L   +      W   I  K K   + ++ E  L++ +   L+++    +A+K +  +       +  + ++  VM L+ + + D      RK+ +D     QR+   +L F    Y  +     +V S  ++ G++  KT +CY    +   C VC + +N+I++ +P +    S L+C  T L +NE N P+  PNG ++      +I  +  T    +++ +
Sbjct:    3 EIKALEHATLKVPYEMLNKRFRSAQKIIDREVDQVINVSRQVEKALEAEEGPILAEVTKLVDNVAQKLQVLKRKAEESINDELSVTQICKRKLDHLKGITPPSSVTGD----------------------LWQ-GSVDQWKR-------IRLDRLVIEHLLRMGYYETAEELAAKSDVR-----HLTNLDIFQTSREVEDDLASHSTTKCVLW--CIDNKSKLRKINSTIEFSLRVQEFIELVRQNQRFEAVKHSRRYF--PAYEKTQLNEICHVMALLAYPA-DAQAEHYRKY-MDP----QRWQKLVLDFRQENYRLFQLSSTSVFSAAVQAGLSALKTPHCYAQTCRNLNCPVCQEDLNRIALKLPYSHCVQSRLICRVTGLPLNEHNQPMMLPNGQIFGQMALPDITKDDGTVTCPVTNTK 382
[Close]
BLAST of Macrophage erythroblast attacher vs. Ensembl Zebrafish
Match: maea (macrophage erythroblast attacher [Source:NCBI gene;Acc:321575])

HSP 1 Score: 120.939 bits (302), Expect = 1.179e-29
Identity = 108/412 (26.21%), Postives = 190/412 (46.12%), Query Frame = 1 
Query:   85 VKLTELTTLKASYEYLNKAYRGNQKSLEKDYQSMVKSIEDYKKANDA----ENAQNCIGLFLENVSNLKRKAETIIAEELNYTKTCKIRLDHLLNLSVSKGNGNNQNCXXXXXXXXXXXXXXXXXSFLYEKGDNMQLKRMDNIDSTVRFQRHLADHLFAQGYCNTAVELAKSINIGENLEDNIGMIEIYQETLDIVEALKKGNFYPVEQWLQSIQFKYKKGDVKNSFESDLQIFKLYLLIKEGNWEKAIKFAHSFCDPKMINEDTMEKLSKVMTLVVFRS------YDELVAAARKWDVDEDWIVQRFHSFILQFYAFYHEPTVLSLMIKTGIAVRKTENCYKPN--MKRKECVVCTDRVNKISVDIPAARHDHSILVCWKTSLEMNEDNPPVAFPNGYVYSTKVWQEIRNN 1284
            +K+ E  TLK  YE LNK +R  QK+++++   +   + + +K   +    +   + +   +E +S LKRKA   I  E    K CK R++HL   S  +    N                      +++K      KRMD         R + +HL   GY NTAV+LA+   I    ED +  IE++    ++ E+L++        W    + + +K  +K+  E  L+I +   LI++     A++ A             ++++ +VM ++ F S      Y +L+  AR W +    ++Q+F     + +   +  +V ++ ++ G++  KT  CYK +   K  +C VC+  +NK++  +P A   +S LVC  +   MNE+NPP+  PNGYVY       IR +
Sbjct:   14 LKVQEYPTLKVPYETLNKRFRAAQKNIDRETSHVTMVVAELEKTLSSFPVVDTVVSLLDGVVEKLSALKRKAAESIQAEDESAKLCKRRIEHLKEHSSDQPASVN----------------------VWKK------KRMD---------RMMVEHLLRCGYYNTAVKLARQSGI----EDLVN-IEMFLTAKEVEESLERQETATCLAWCHDNKSRLRK--MKSCLEFSLRIQEFIELIRQNKRMDAVRHARKHFS--QAEGGQLDEVRQVMGMLAFPSDTHISPYKDLLDPAR-WKM----LIQQFRYDNYRLHQLGNN-SVFTITLQAGLSAIKTPQCYKEDGTSKNPDCPVCSKSLNKLAQPLPMAHCANSRLVCKISGEVMNENNPPMMLPNGYVYGYNSLLSIRQD 373
[Close]
BLAST of Macrophage erythroblast attacher vs. Ensembl Xenopus
Match: maea (macrophage erythroblast attacher [Source:NCBI gene;Acc:493335])

HSP 1 Score: 115.161 bits (287), Expect = 1.995e-27
Identity = 111/425 (26.12%), Postives = 193/425 (45.41%), Query Frame = 1 
Query:   85 VKLTELTTLKASYEYLNKAYRGNQKSLEKDYQSMVKSIEDYKKANDAENAQNCIGLFLENV----SNLKRKAETIIAEELNYTKTCKIRLDHLLNLSVSKGNGNNQNCXXXXXXXXXXXXXXXXXSFLYEKGDNMQLKRMDNIDSTVRFQRHLADHLFAQGYCNTAVELAKSINIGENLEDNIGMIEIYQETLDIVEALKKGNFYPVEQWLQSIQFKYKKG-------------DVKNSFESDLQIFKLYLLIKEGNWEKAIKFAHSFCDPKMINEDTMEKLSKVMTLVVFRS------YDELVAAARKWDVDEDWIVQRFHSFILQFYAFYHEPTVLSLMIKTGIAVRKTENCYKPN--MKRKECVVCTDRVNKISVDIPAARHDHSILVCWKTSLEMNEDNPPVAFPNGYVYSTKVWQEIRNN 1284
            +K+ E  TLK  YE LNK +R  QK+++++   +   + + +K   + +A + +   L+ V    S LKRKA   I  E    K CK R++HL      K + N+Q   +                 +++K      KRMD         R + +HL   GY NTAV+LA+   I    ED +  IE++    ++ E+L++        W    + + +K              D  +  E  L+I +   LI++     A++ A             ++++ +VM ++ F S      Y +L+  AR W +    ++Q+F     + +   +  +V ++ ++ G++  KT  CYK +   K  +C VC+  +NK++  +P A   +S LVC  +   MNE+NPP+  PNGYVY       IR +
Sbjct:   14 LKVQEYPTLKVPYETLNKRFRAAQKNIDRETSHVTMVVAELEKTLSSCSAVDSVVSLLDGVVEKLSVLKRKAVESIQAEDESAKLCKRRIEHL------KEHSNDQVAAIN----------------MWKK------KRMD---------RMMVEHLLRCGYYNTAVKLARQSGI----EDLVN-IEMFLTAKEVEESLERQETMTCLAWCHDNKSRLRKMKVCVAHWSEGCMLDQLSCLEFSLRIQEFIELIRQNKRLDAVRHARKHFS--QAEGSQLDEVRQVMGMLAFPSDTHISPYKDLLDPAR-WRM----LIQQFRYDNYRLHQLGNN-SVFTITLQAGLSAIKTPQCYKEDGTSKNPDCPVCSKSLNKLAQPLPMAHCANSRLVCKISGDVMNENNPPMMLPNGYVYGYNSLLSIRQD 388
[Close]
BLAST of Macrophage erythroblast attacher vs. Ensembl Xenopus
Match: maea (macrophage erythroblast attacher [Source:NCBI gene;Acc:493335])

HSP 1 Score: 110.153 bits (274), Expect = 1.417e-25
Identity = 113/442 (25.57%), Postives = 198/442 (44.80%), Query Frame = 1 
Query:   85 VKLTELTTLKASYEYLNKAYRGNQKSLEKDYQSMVKSIEDYKKANDAENAQNCIGLFLENV----SNLKRKA------------------------------ETIIAEELNYTKTCKIRLDHLLNLSVSKGNGNNQNCXXXXXXXXXXXXXXXXXSFLYEKGDNMQLKRMDNIDSTVRFQRHLADHLFAQGYCNTAVELAKSINIGENLEDNIGMIEIYQETLDIVEALKKGNFYPVEQWLQSIQFKYKKGDVKNSFESDLQIFKLYLLIKEGNWEKAIKFAHSFCDPKMINEDTMEKLSKVMTLVVFRS------YDELVAAARKWDVDEDWIVQRFHSFILQFYAFYHEPTVLSLMIKTGIAVRKTENCYKPN--MKRKECVVCTDRVNKISVDIPAARHDHSILVCWKTSLEMNEDNPPVAFPNGYVYSTKVWQEIRNN 1284
            +K+ E  TLK  YE LNK +R  QK+++++   +   + + +K   + +A + +   L+ V    S LKRKA                              E+I AE+    K CK R++HL      K + N+Q   +                 +++K      KRMD         R + +HL   GY NTAV+LA+   I    ED +  IE++    ++ E+L++        W    + + +K  +K+  E  L+I +   LI++     A++ A             ++++ +VM ++ F S      Y +L+  AR W +    ++Q+F     + +   +  +V ++ ++ G++  KT  CYK +   K  +C VC+  +NK++  +P A   +S LVC  +   MNE+NPP+  PNGYVY       IR +
Sbjct:   14 LKVQEYPTLKVPYETLNKRFRAAQKNIDRETSHVTMVVAELEKTLSSCSAVDSVVSLLDGVVEKLSVLKRKAVIQPHSHIPSPSTMESKVPESITPQWNKAVESIQAED-ESAKLCKRRIEHL------KEHSNDQVAAIN----------------MWKK------KRMD---------RMMVEHLLRCGYYNTAVKLARQSGI----EDLVN-IEMFLTAKEVEESLERQETMTCLAWCHDNKSRLRK--MKSCLEFSLRIQEFIELIRQNKRLDAVRHARKHFS--QAEGSQLDEVRQVMGMLAFPSDTHISPYKDLLDPAR-WRM----LIQQFRYDNYRLHQLGNN-SVFTITLQAGLSAIKTPQCYKEDGTSKNPDCPVCSKSLNKLAQPLPMAHCANSRLVCKISGDVMNENNPPMMLPNGYVYGYNSLLSIRQD 402
[Close]
BLAST of Macrophage erythroblast attacher vs. Ensembl Mouse
Match: Maea (macrophage erythroblast attacher [Source:MGI Symbol;Acc:MGI:1891748])

HSP 1 Score: 119.398 bits (298), Expect = 4.518e-29
Identity = 109/412 (26.46%), Postives = 194/412 (47.09%), Query Frame = 1 
Query:   85 VKLTELTTLKASYEYLNKAYRGNQKSLEKDYQSMVKSIEDYKKANDAENAQNCIGLFLENV----SNLKRKAETIIAEELNYTKTCKIRLDHLLNLSVSKGNGNNQNCXXXXXXXXXXXXXXXXXSFLYEKGDNMQLKRMDNIDSTVRFQRHLADHLFAQGYCNTAVELAKSINIGENLEDNIGMIEIYQETLDIVEALKKGNFYPVEQWLQSIQFKYKKGDVKNSFESDLQIFKLYLLIKEGNWEKAIKFAHSFCDPKMINEDTMEKLSKVMTLVVF------RSYDELVAAARKWDVDEDWIVQRFHSFILQFYAFYHEPTVLSLMIKTGIAVRKTENCYKPN--MKRKECVVCTDRVNKISVDIPAARHDHSILVCWKTSLEMNEDNPPVAFPNGYVYSTKVWQEIRNN 1284
            +K+ E  TLK  YE LNK +R  QK+++++   +   + + +K   +  A + +   L+ V    S LKRKA   I  E    K CK R++HL      K + ++Q                P ++ ++++      KRMD         R + +HL   GY NTAV+LA+   I    ED +  IE++    ++ E+L++        W    + + +K  +K+  E  L+I +   L+++     A++ A             ++++ +VM ++ F        Y +L+  AR W +    ++Q+F     + +   +  +V +L ++ G++  KT  CYK +   K  +C VC+  +NK++  +P A   +S LVC  +   MNE+NPP+  PNGYVY       IR +
Sbjct:   14 LKVQEYPTLKVPYETLNKRFRAAQKNIDRETSHVTMVVAELEKTLSSCPAVDSVVSLLDGVVEKLSVLKRKAVESIQAEDESAKLCKRRIEHL------KEHSSDQ----------------PAAASMWKR------KRMD---------RMMVEHLLRCGYYNTAVKLARQSGI----EDLVN-IEMFLTAKEVEESLERRETATCLAWCHDNKSRLRK--MKSCLEFSLRIQEFIELVRQNKRLDAVRHARKHFS--QAEGSQLDEVRQVMGMLAFPPDTHISPYKDLLDPAR-WRM----LIQQFRYDNYRLHQLGNS-SVFTLTLQAGLSAIKTPQCYKEDGSSKSPDCPVCSRSLNKLAQPLPMAHCANSRLVCKISGDVMNENNPPMMLPNGYVYGYNSLLSIRQD 373
[Close]
BLAST of Macrophage erythroblast attacher vs. Ensembl Mouse
Match: Maea (macrophage erythroblast attacher [Source:MGI Symbol;Acc:MGI:1891748])

HSP 1 Score: 51.2174 bits (121), Expect = 2.174e-7
Identity = 48/175 (27.43%), Postives = 79/175 (45.14%), Query Frame = 1 
Query:   85 VKLTELTTLKASYEYLNKAYRGNQKSLEKDYQSMVKSIEDYKKANDAENAQNCIGLFLENV----SNLKRKAETIIAEELNYTKTCKIRLDHLLNLSVSKGNGNNQNCXXXXXXXXXXXXXXXXXSFLYEKGDNMQLKRMDNIDSTVRFQRHLADHLFAQGYCNTAVELAKSINI 597
            +K+ E  TLK  YE LNK +R  QK+++++   +   + + +K   +  A + +   L+ V    S LKRKAE          K CK R++HL      K + ++Q                  ++ ++++      KRMD         R + +HL   GY NTAV+LA+   I
Sbjct:   14 LKVQEYPTLKVPYETLNKRFRAAQKNIDRETSHVTMVVAELEKTLSSCPAVDSVVSLLDGVVEKLSVLKRKAED------ESAKLCKRRIEHL------KEHSSDQPA----------------AASMWKR------KRMD---------RMMVEHLLRCGYYNTAVKLARQSGI 145
[Close]
BLAST of Macrophage erythroblast attacher vs. UniProt/SwissProt
Match: sp|Q5F398|MAEA_CHICK (E3 ubiquitin-protein transferase MAEA OS=Gallus gallus OX=9031 GN=MAEA PE=2 SV=1)

HSP 1 Score: 122.094 bits (305), Expect = 3.448e-29
Identity = 110/412 (26.70%), Postives = 190/412 (46.12%), Query Frame = 1 
Query:   85 VKLTELTTLKASYEYLNKAYRGNQKSLEKDYQSMVKSIEDYKKANDAENAQNCIGLFLENV----SNLKRKAETIIAEELNYTKTCKIRLDHLLNLSVSKGNGNNQNCXXXXXXXXXXXXXXXXXSFLYEKGDNMQLKRMDNIDSTVRFQRHLADHLFAQGYCNTAVELAKSINIGENLEDNIGMIEIYQETLDIVEALKKGNFYPVEQWLQSIQFKYKKGDVKNSFESDLQIFKLYLLIKEGNWEKAIKFAHSFCDPKMINEDTMEKLSKVMTLVVFRS------YDELVAAARKWDVDEDWIVQRFHSFILQFYAFYHEPTVLSLMIKTGIAVRKTENCYKPN--MKRKECVVCTDRVNKISVDIPAARHDHSILVCWKTSLEMNEDNPPVAFPNGYVYSTKVWQEIRNN 1284
            +K+ E  TLK  YE LNK +R  QK+++++   +   + + +K   +  A + +   L+ V    S LKRKA   I  E    K CK R++HL   S  +    N                      +++K      KRMD         R + +HL   GY NTAV+LA+   I    ED +  IE++    ++ E+L++        W    + + +K  +K+  E  L+I +   LI++     A++ A             ++++ +VM ++ F S      Y +L+  AR W +    ++Q+F     + +   +  +V ++ ++ G++  KT  CYK +   K  +C VC+  +NK++  +P A   +S LVC  +   MNE+NPP+  PNGYVY       IR +
Sbjct:   14 LKVQEYPTLKVPYETLNKRFRAAQKNIDRETSHVTMVVAELEKTLSSCPAVDSVVSLLDGVVEKLSVLKRKAVESIQAEDESAKLCKRRIEHLKEHSSDQPAAAN----------------------MWKK------KRMD---------RMMVEHLLRCGYYNTAVKLARQSGI----EDLVN-IEMFLTAKEVEESLERQETMTCLAWCHDNKSRLRK--MKSCLEFSLRIQEFIELIRQNKRLDAVRHARKHFS--QAEGSQLDEVRQVMGMLAFPSDTHISPYKDLLDPAR-WRM----LIQQFRYDNYRLHQLGNN-SVFTITLQAGLSAIKTPQCYKEDGSSKNPDCPVCSKSLNKLAQPLPMAHCANSRLVCKISGDVMNENNPPMMLPNGYVYGYNSLLSIRQD 373
[Close]
BLAST of Macrophage erythroblast attacher vs. UniProt/SwissProt
Match: sp|Q6GR10|MAEA_XENLA (E3 ubiquitin-protein transferase MAEA OS=Xenopus laevis OX=8355 GN=maea PE=2 SV=2)

HSP 1 Score: 121.324 bits (303), Expect = 5.733e-29
Identity = 110/412 (26.70%), Postives = 191/412 (46.36%), Query Frame = 1 
Query:   85 VKLTELTTLKASYEYLNKAYRGNQKSLEKDYQSMVKSIEDYKKANDAENAQNCIGLFLENV----SNLKRKAETIIAEELNYTKTCKIRLDHLLNLSVSKGNGNNQNCXXXXXXXXXXXXXXXXXSFLYEKGDNMQLKRMDNIDSTVRFQRHLADHLFAQGYCNTAVELAKSINIGENLEDNIGMIEIYQETLDIVEALKKGNFYPVEQWLQSIQFKYKKGDVKNSFESDLQIFKLYLLIKEGNWEKAIKFAHSFCDPKMINEDTMEKLSKVMTLVVFRS------YDELVAAARKWDVDEDWIVQRFHSFILQFYAFYHEPTVLSLMIKTGIAVRKTENCYKPN--MKRKECVVCTDRVNKISVDIPAARHDHSILVCWKTSLEMNEDNPPVAFPNGYVYSTKVWQEIRNN 1284
            +K+ E  TLK  YE LNK +R  QK+++++   +   + + +K   + +A + +   L+ V    S LKRKA   I  E    K CK R++HL   S  +    N                      +++K      KRMD         R + +HL   GY NTAV+LA+   I    ED +  IE++    ++ E+L++        W    + + +K  +K+  E  L+I +   LI++     A++ A             ++++ +VM ++ F S      Y +L+  AR W +    ++Q+F     + +   +  +V ++ ++ G++  KT  CYK +   K  +C VC+  +NK++  +P A   +S LVC  +   MNE+NPP+  PNGYVY       IR +
Sbjct:   14 LKVQEYPTLKVPYETLNKRFRAAQKNIDRETSHVTMVVAELEKTLSSCSAVDSVVSLLDGVVEKLSVLKRKAMESIQAEDESAKLCKRRIEHLKEHSSDQTAAIN----------------------MWKK------KRMD---------RMMVEHLLRCGYYNTAVKLARQSEI----EDLVN-IEMFLTAKEVEESLERQETMTCLAWCHDNKSRLRK--MKSCLEFSLRIQEFIELIRQNKRLDAVRHARKHFS--QAEGSQLDEVRQVMGMLAFPSDTHISPYKDLLDPAR-WRM----LIQQFRYDNYRLHQLGNN-SVFTITLQAGLSAIKTPQCYKEDGTSKNPDCPVCSKSLNKLAQPLPLAHCANSRLVCKISGDVMNENNPPMMLPNGYVYGYNSLLSIRQD 373
[Close]
BLAST of Macrophage erythroblast attacher vs. UniProt/SwissProt
Match: sp|Q7SXR3|MAEA_DANRE (E3 ubiquitin-protein transferase MAEA OS=Danio rerio OX=7955 GN=maea PE=2 SV=2)

HSP 1 Score: 120.939 bits (302), Expect = 8.898e-29
Identity = 108/412 (26.21%), Postives = 190/412 (46.12%), Query Frame = 1 
Query:   85 VKLTELTTLKASYEYLNKAYRGNQKSLEKDYQSMVKSIEDYKKANDA----ENAQNCIGLFLENVSNLKRKAETIIAEELNYTKTCKIRLDHLLNLSVSKGNGNNQNCXXXXXXXXXXXXXXXXXSFLYEKGDNMQLKRMDNIDSTVRFQRHLADHLFAQGYCNTAVELAKSINIGENLEDNIGMIEIYQETLDIVEALKKGNFYPVEQWLQSIQFKYKKGDVKNSFESDLQIFKLYLLIKEGNWEKAIKFAHSFCDPKMINEDTMEKLSKVMTLVVFRS------YDELVAAARKWDVDEDWIVQRFHSFILQFYAFYHEPTVLSLMIKTGIAVRKTENCYKPN--MKRKECVVCTDRVNKISVDIPAARHDHSILVCWKTSLEMNEDNPPVAFPNGYVYSTKVWQEIRNN 1284
            +K+ E  TLK  YE LNK +R  QK+++++   +   + + +K   +    +   + +   +E +S LKRKA   I  E    K CK R++HL   S  +    N                      +++K      KRMD         R + +HL   GY NTAV+LA+   I    ED +  IE++    ++ E+L++        W    + + +K  +K+  E  L+I +   LI++     A++ A             ++++ +VM ++ F S      Y +L+  AR W +    ++Q+F     + +   +  +V ++ ++ G++  KT  CYK +   K  +C VC+  +NK++  +P A   +S LVC  +   MNE+NPP+  PNGYVY       IR +
Sbjct:   14 LKVQEYPTLKVPYETLNKRFRAAQKNIDRETSHVTMVVAELEKTLSSFPVVDTVVSLLDGVVEKLSALKRKAAESIQAEDESAKLCKRRIEHLKEHSSDQPASVN----------------------VWKK------KRMD---------RMMVEHLLRCGYYNTAVKLARQSGI----EDLVN-IEMFLTAKEVEESLERQETATCLAWCHDNKSRLRK--MKSCLEFSLRIQEFIELIRQNKRMDAVRHARKHFS--QAEGGQLDEVRQVMGMLAFPSDTHISPYKDLLDPAR-WKM----LIQQFRYDNYRLHQLGNN-SVFTITLQAGLSAIKTPQCYKEDGTSKNPDCPVCSKSLNKLAQPLPMAHCANSRLVCKISGEVMNENNPPMMLPNGYVYGYNSLLSIRQD 373
[Close]
BLAST of Macrophage erythroblast attacher vs. UniProt/SwissProt
Match: sp|Q5RKJ1|MAEA_RAT (E3 ubiquitin-protein transferase MAEA OS=Rattus norvegicus OX=10116 GN=Maea PE=2 SV=2)

HSP 1 Score: 119.398 bits (298), Expect = 3.160e-28
Identity = 109/412 (26.46%), Postives = 194/412 (47.09%), Query Frame = 1 
Query:   85 VKLTELTTLKASYEYLNKAYRGNQKSLEKDYQSMVKSIEDYKKANDAENAQNCIGLFLENV----SNLKRKAETIIAEELNYTKTCKIRLDHLLNLSVSKGNGNNQNCXXXXXXXXXXXXXXXXXSFLYEKGDNMQLKRMDNIDSTVRFQRHLADHLFAQGYCNTAVELAKSINIGENLEDNIGMIEIYQETLDIVEALKKGNFYPVEQWLQSIQFKYKKGDVKNSFESDLQIFKLYLLIKEGNWEKAIKFAHSFCDPKMINEDTMEKLSKVMTLVVF------RSYDELVAAARKWDVDEDWIVQRFHSFILQFYAFYHEPTVLSLMIKTGIAVRKTENCYKPN--MKRKECVVCTDRVNKISVDIPAARHDHSILVCWKTSLEMNEDNPPVAFPNGYVYSTKVWQEIRNN 1284
            +K+ E  TLK  YE LNK +R  QK+++++   +   + + +K   +  A + +   L+ V    S LKRKA   I  E    K CK R++HL      K + ++Q                P ++ ++++      KRMD         R + +HL   GY NTAV+LA+   I    ED +  IE++    ++ E+L++        W    + + +K  +K+  E  L+I +   L+++     A++ A             ++++ +VM ++ F        Y +L+  AR W +    ++Q+F     + +   +  +V +L ++ G++  KT  CYK +   K  +C VC+  +NK++  +P A   +S LVC  +   MNE+NPP+  PNGYVY       IR +
Sbjct:   14 LKVQEYPTLKVPYETLNKRFRAAQKNIDRETSHVTMVVAELEKTLSSCPAVDSVVSLLDGVVEKLSVLKRKAVESIQAEDESAKLCKRRIEHL------KEHSSDQ----------------PAAASMWKR------KRMD---------RMMVEHLLRCGYYNTAVKLARQSGI----EDLVN-IEMFLTAKEVEESLERRETATCLAWCHDNKSRLRK--MKSCLEFSLRIQEFIELVRQNKRLDAVRHARKHFS--QAEGSQLDEVRQVMGMLAFPPDTHISPYKDLLDPAR-WRM----LIQQFRYDNYRLHQLGNS-SVFTLTLQAGLSAIKTPQCYKEDGSSKSPDCPVCSRSLNKLAQPLPMAHCANSRLVCKISGDVMNENNPPMMLPNGYVYGYNSLLSIRQD 373
[Close]
BLAST of Macrophage erythroblast attacher vs. UniProt/SwissProt
Match: sp|Q4VC33|MAEA_MOUSE (E3 ubiquitin-protein transferase MAEA OS=Mus musculus OX=10090 GN=Maea PE=1 SV=1)

HSP 1 Score: 119.398 bits (298), Expect = 3.160e-28
Identity = 109/412 (26.46%), Postives = 194/412 (47.09%), Query Frame = 1 
Query:   85 VKLTELTTLKASYEYLNKAYRGNQKSLEKDYQSMVKSIEDYKKANDAENAQNCIGLFLENV----SNLKRKAETIIAEELNYTKTCKIRLDHLLNLSVSKGNGNNQNCXXXXXXXXXXXXXXXXXSFLYEKGDNMQLKRMDNIDSTVRFQRHLADHLFAQGYCNTAVELAKSINIGENLEDNIGMIEIYQETLDIVEALKKGNFYPVEQWLQSIQFKYKKGDVKNSFESDLQIFKLYLLIKEGNWEKAIKFAHSFCDPKMINEDTMEKLSKVMTLVVF------RSYDELVAAARKWDVDEDWIVQRFHSFILQFYAFYHEPTVLSLMIKTGIAVRKTENCYKPN--MKRKECVVCTDRVNKISVDIPAARHDHSILVCWKTSLEMNEDNPPVAFPNGYVYSTKVWQEIRNN 1284
            +K+ E  TLK  YE LNK +R  QK+++++   +   + + +K   +  A + +   L+ V    S LKRKA   I  E    K CK R++HL      K + ++Q                P ++ ++++      KRMD         R + +HL   GY NTAV+LA+   I    ED +  IE++    ++ E+L++        W    + + +K  +K+  E  L+I +   L+++     A++ A             ++++ +VM ++ F        Y +L+  AR W +    ++Q+F     + +   +  +V +L ++ G++  KT  CYK +   K  +C VC+  +NK++  +P A   +S LVC  +   MNE+NPP+  PNGYVY       IR +
Sbjct:   14 LKVQEYPTLKVPYETLNKRFRAAQKNIDRETSHVTMVVAELEKTLSSCPAVDSVVSLLDGVVEKLSVLKRKAVESIQAEDESAKLCKRRIEHL------KEHSSDQ----------------PAAASMWKR------KRMD---------RMMVEHLLRCGYYNTAVKLARQSGI----EDLVN-IEMFLTAKEVEESLERRETATCLAWCHDNKSRLRK--MKSCLEFSLRIQEFIELVRQNKRLDAVRHARKHFS--QAEGSQLDEVRQVMGMLAFPPDTHISPYKDLLDPAR-WRM----LIQQFRYDNYRLHQLGNS-SVFTLTLQAGLSAIKTPQCYKEDGSSKSPDCPVCSRSLNKLAQPLPMAHCANSRLVCKISGDVMNENNPPMMLPNGYVYGYNSLLSIRQD 373
[Close]
BLAST of Macrophage erythroblast attacher vs. TrEMBL
Match: G4V5H0 (Putative erythroblast macrophage protein emp OS=Schistosoma mansoni OX=6183 GN=Smp_008470.2 PE=4 SV=1)

HSP 1 Score: 256.529 bits (654), Expect = 7.082e-77
Identity = 149/404 (36.88%), Postives = 228/404 (56.44%), Query Frame = 1 
Query:   76 QDEVKLTELTTLKASYEYLNKAYRGNQKSLEKDYQSMVKSIEDYKKANDAENAQNCIGLFLENVSNLKRKAETIIAEELNYTKTCKIRLDHLLNLSVSKGNGNNQNCXXXXXXXXXXXXXXXXXSFLYEKGDNMQLKRMD--NIDSTV----RFQRHLADHLFAQGYCNTAVELAKS-INIGENLEDNIGMIEIYQETLDIVEALKKGNFYPVEQWLQSIQFKYKKGDVKNSFESDLQIFKLYLLIKEGNWEKAIKFAHSFCDP-KMINEDTMEKLSKVMTLVVFRSYDELVAAARKWDVDEDWIVQRFHSFILQFYAFYHEPTVLSLMIKTGIAVRKTENCYKPNMKRKECVVCTDRVNKISVDIPAARHDHSILVCWKTSLEMNEDNPPVAFPNGYVYSTKV 1263
            Q+EV++ E TT+KASYE LNK YR N + +EK   ++ KS+++ + A D   A   +   +E V  +KRKAE +  EE    K+CK R+ HL  L +       +  D   F+           S +     +  LKR    ++D       RFQRHL D+LF  G   +A++ A+    +G+     + M+E++ E + I +AL +G+  P   WLQ   FK KK D  + +E DL++F+ YLL+K+G   +AI+ A  + +  K  ++    KL + M L+  R+ +EL   A +  + E+WIV+R H  +++FYA Y+  T   L +  GI   KT  CY PN + ++C VC   +N ++V++P ARHDHSIL C+KT L MN++NPP++ PNGYVYS KV
Sbjct:    8 QNEVEVMEYTTVKASYESLNKRYRRNHRDMEKGIAALNKSLDELENATDITKATAALSRVIETVCGVKRKAEYVCIEERKLLKSCKRRIGHLSQLCLLDSGVFTRTSDELHFNAGNNQKSEESISKVNSSESDTTLKRRSTYSVDERALCLARFQRHLTDYLFTSGQPLSALKFAQEKAELGD-----LCMMEVFDEAVSIEKALLEGDTGPAFSWLQEANFKLKKND--SYYEFDLRVFEFYLLVKQGKRIEAIQHARKYMNSVKQADDYRATKLGQAMILLAMRTPEELQNKADQNKLTEEWIVKRTHEVLMEFYA-YNVNTPFQLAVNAGITAIKTHYCYNPNTQHRDCAVCHPLINLLAVNLPFARHDHSILTCYKTGLPMNDENPPMSLPNGYVYSQKV 403
[Close]
BLAST of Macrophage erythroblast attacher vs. TrEMBL
Match: A0A3Q0KC39 (Putative erythroblast macrophage protein emp OS=Schistosoma mansoni OX=6183 PE=4 SV=1)

HSP 1 Score: 255.758 bits (652), Expect = 2.640e-76
Identity = 149/408 (36.52%), Postives = 229/408 (56.13%), Query Frame = 1 
Query:   76 QDEVKLTELTTLKASYEYLNKAYRGNQKSLEKDYQSMVKSIEDYKKANDAENAQNCIGLFLENVSNLKRKAETIIAEELNYTKTCKIRLDHLLNLSVSKGNGNNQNCXXXXXXXXXXXXXXXXXSFLYEKGDNMQLKRMD--NIDSTV----RFQRHLADHLFAQGYCNTAVELAKS-INIGENLEDNIGMIEIYQETLDIVEALKKGNFYPVEQWLQSIQFKYKKGDVKNSFESDLQIFKLYLLIKEGNWEKAIKFAHSFCDP-KMINEDTMEKLSKVMTLVVFRSYDELVAAARKWDVDEDWIVQRFHSFILQFYAFYHEPTVLSLMIKTGIAVRKTENCYKPNMKRKECVVCTDRVNKISVDIPAARHDHSILVCWKTSLEMNEDNPPVAFPNGYVYSTKVWQEI 1275
            Q+EV++ E TT+KASYE LNK YR N + +EK   ++ KS+++ + A D   A   +   +E V  +KRKAE +  EE    K+CK R+ HL  L +       +  D   F+           S +     +  LKR    ++D       RFQRHL D+LF  G   +A++ A+    +G+     + M+E++ E + I +AL +G+  P   WLQ   FK KK D  + +E DL++F+ YLL+K+G   +AI+ A  + +  K  ++    KL + M L+  R+ +EL   A +  + E+WIV+R H  +++FYA Y+  T   L +  GI   KT  CY PN + ++C VC   +N ++V++P ARHDHSIL C+KT L MN++NPP++ PNGYVYS K   E+
Sbjct:    8 QNEVEVMEYTTVKASYESLNKRYRRNHRDMEKGIAALNKSLDELENATDITKATAALSRVIETVCGVKRKAEYVCIEERKLLKSCKRRIGHLSQLCLLDSGVFTRTSDELHFNAGNNQKSEESISKVNSSESDTTLKRRSTYSVDERALCLARFQRHLTDYLFTSGQPLSALKFAQEKAELGD-----LCMMEVFDEAVSIEKALLEGDTGPAFSWLQEANFKLKKND--SYYEFDLRVFEFYLLVKQGKRIEAIQHARKYMNSVKQADDYRATKLGQAMILLAMRTPEELQNKADQNKLTEEWIVKRTHEVLMEFYA-YNVNTPFQLAVNAGITAIKTHYCYNPNTQHRDCAVCHPLINLLAVNLPFARHDHSILTCYKTGLPMNDENPPMSLPNGYVYSQKGIAEL 407
[Close]
BLAST of Macrophage erythroblast attacher vs. TrEMBL
Match: A0A4Z2DDB0 (Macrophage erythroblast attacher OS=Schistosoma japonicum OX=6182 GN=EWB00_002131 PE=4 SV=1)

HSP 1 Score: 251.136 bits (640), Expect = 1.747e-74
Identity = 147/409 (35.94%), Postives = 229/409 (55.99%), Query Frame = 1 
Query:   76 QDEVKLTELTTLKASYEYLNKAYRGNQKSLEKDYQSMVKSIEDYKKANDAENAQNCIGLFLENVSNLKRKAETIIAEELNYTKTCKIRLDHLLNLSVSKGNGNNQNCXXXXXXXXXXXXXXXXXSFLYEKGDN---MQLKRMDNIDSTV----RFQRHLADHLFAQGYCNTAVELAKS-INIGENLEDNIGMIEIYQETLDIVEALKKGNFYPVEQWLQSIQFKYKKGDVKNSFESDLQIFKLYLLIKEGNWEKAIKFAHSFCDP-KMINEDTMEKLSKVMTLVVFRSYDELVAAARKWDVDEDWIVQRFHSFILQFYAFYHEPTVLSLMIKTGIAVRKTENCYKPNMKRKECVVCTDRVNKISVDIPAARHDHSILVCWKTSLEMNEDNPPVAFPNGYVYSTKVWQEI 1275
            Q+EV++ E TT+KASYE LNK YR N + +EK   ++ KS+++ + A D   A   +   LE V   KRKAE +  EE    K+CK R+ HL  L +      ++N D                 + +  G++   ++ + ++  D       RFQRHL D+LF  G   +A++ A+    +G+     + M+E++ E + I +AL +G+  P   WLQ   FK KK D  + +E DL++F+ YLL+K+G   +AI+ A  + +  K  ++    KL + M L+  R+ +EL   A +  + E WIV+R H  +++FYA Y   T   L +  GI   KT  CY PN + ++C VC   +N+++V++P ARHDHSIL C+KT L MN++NPP++ PNGYVYS K   E+
Sbjct:    8 QNEVEIMEYTTVKASYESLNKRYRRNHRDMEKGIAALNKSLDELENAKDITKATVALSKVLETVCGAKRKAEYVCFEERKLLKSCKRRIGHLSQLYLLDSGSFSRNSDEMNLDNAHNQKTEDLM-YKFSSGESDTTLKPRSVNAFDERALCLARFQRHLTDYLFTSGQPLSALKFAQEKPELGD-----LCMMEVFDEAVIIEKALLEGDTGPAFSWLQEANFKLKKND--SYYEFDLRVFEFYLLVKQGKRIEAIQHARKYMNSVKQADDYRATKLGQAMILLAMRTPEELQNKADQNKLTEKWIVKRTHEVLMEFYA-YSIYTPFQLAVNAGITAIKTHYCYNPNTQHRDCAVCHPLINQLAVNLPFARHDHSILTCYKTGLPMNDENPPMSLPNGYVYSQKGIAEL 407
[Close]
BLAST of Macrophage erythroblast attacher vs. TrEMBL
Match: A0A430QFP2 (Macrophage erythroblast attacher OS=Schistosoma bovis OX=6184 GN=DC041_0008315 PE=4 SV=1)

HSP 1 Score: 246.514 bits (628), Expect = 2.681e-72
Identity = 150/424 (35.38%), Postives = 229/424 (54.01%), Query Frame = 1 
Query:   76 QDEVKLTELTTLKASYEYLNKAYRGNQKSLEKDYQSMVKSIEDYKKANDAENAQNCIGLFLENVSNLKRKAETIIAEELNYTKTCKIRLDHLLNLSVSKGNGNNQNCXXXXXXXXXXXXXXXXXSFLYEKGDNMQLKRMD--NIDSTV----RFQRHLADHLFAQGYCNTAVELAKS-INIGENLEDNIGMIEIYQETLDIVEALKKGNFYPVEQWLQSIQFKYKKGDVKNSFESDLQIFKLYLLIKEGNWEKAIKFAHSFCDP-KMINEDTMEKLSKVMTLVVFRSYDELVAAA----------------RKWDVDEDWIVQRFHSFILQFYAFYHEPTVLSLMIKTGIAVRKTENCYKPNMKRKECVVCTDRVNKISVDIPAARHDHSILVCWKTSLEMNEDNPPVAFPNGYVYSTKVWQEI 1275
            Q+EV++ E TT+KASYE LNK YR N + +EK   ++ KS+++ + A D   A   +   LE V  +KRKAE +  EE    K+CK R+ HL  L +       +  D   F+           S +     +  LKR    ++D       RFQRHL D+LF  G   +A++ A+    +G+     + M+E++ E + I +AL +G+  P   WLQ   FK KK D  + +E DL++F+ YLL+K+G   +AI+ A  + +  K  ++    KL + M L+  R+ +EL   A                 +  + E+WIV+R H  +++FYA Y+  T   L +  GI   KT  CY PN + ++C VC   +N ++V++P ARHDHSIL C+KT L MN++NPP++ PNGYVYS K   E+
Sbjct:   26 QNEVEVMEYTTVKASYESLNKRYRRNHRDMEKGIAALNKSLDELENATDITKATAALSRVLETVCGVKRKAEFVCIEERKLLKSCKRRIGHLSQLCLLDSGMFTRASDELHFNASSNQKSEESISKVNSSESDTTLKRRSTYSVDERALCLARFQRHLTDYLFTSGQPLSALKFAQEKAELGD-----LCMMEVFDEAVSIEKALLEGDTGPAFSWLQEANFKLKKND--SYYEFDLRVFEFYLLVKQGKRIEAIQHARKYMNSVKQADDYRATKLGQAMILLAMRTPEELQNKAVCLIFLILLKSYLLFMDQNKLTEEWIVKRTHEVLMEFYA-YNINTPFQLAVNAGITAIKTHYCYNPNTQHRDCAVCHPLINMLAVNLPFARHDHSILTCYKTGLPMNDENPPMSLPNGYVYSQKGIAEL 441
[Close]
BLAST of Macrophage erythroblast attacher vs. TrEMBL
Match: A0A0R3X4B7 (CTLH domain-containing protein OS=Hydatigena taeniaeformis OX=6205 GN=TTAC_LOCUS8230 PE=4 SV=1)

HSP 1 Score: 244.973 bits (624), Expect = 1.206e-71
Identity = 140/417 (33.57%), Postives = 226/417 (54.20%), Query Frame = 1 
Query:   82 EVKLTELTTLKASYEYLNKAYRGNQKSLEKDYQSMVKSIEDYKKANDAENAQNCIGLFLENVSNLKRKAETIIAEELNYTKTCKIRLDHLLNLSVSKGNGNNQNCXXXXXXXXXXXXXXXXXSFLYEKGDNMQLKRMDNIDSTV---------RFQRHLADHLFAQGYCNTAVELAKSINIGENLEDNIGMIEIYQETLDIVEALKKGNFYPVEQWLQSIQFKYKKGDVKNSFESDLQIFKLYLLIKEGNWEKAIKFAHSFCDPKMINED-TMEKLSKVMTLVVFRSYDELVAAARKWDVDEDWIVQRFHSFILQFYAFYHEPTVLSLMIKTGIAVRKTENCYKPNMKRKECVVCTDRVNKISVDIPAARHDHSILVCWKTSLEMNEDNPPVAFPNGYVYSTKVWQEIRNNSVTFAL 1302
            E++LTE   +KA YE LNK YR N + LEK   ++ + I+ +   N +E A   IG  +  V   KRKA+ I  EE+    +CK R+D L  +S  +G  +++ C L    L          S + E+G+    +   NI             R  R LA+HLFA G+  +A+ LA+     + +      I I++E L I EAL +G+  P  +W Q  +F+ K  +   +F+ DL++F+ YLL+K     +A++ +  +      ++D    +L + M L++ R+ +E+ A A + +++E WI++RFH  ++ FY+F   PT  SL ++ GI   KT  CY    +  +CVVC   +N+ + ++   R+DHS+L C++T L MN+DNPP+A PNGYVYS +  +E    S +FAL
Sbjct:    9 EIELTEYMGMKAVYELLNKKYRVNHRELEKHSANLNRIIDRFNDVNTSEEAAEFIGRVITAVRGSKRKADEIFTEEMELVASCKRRIDSLKEVSDFEGKASSKPCGLGTAMLAADQVE----SVVTERGNKPSNQPKVNISPKAESEQRVFASRCNRLLAEHLFAVGHYRSALALARQCPDADKI-----FIGIFEEALSIQEALSRGDTEPAHKWFQETKFRLKHAEC--TFDFDLRVFEFYLLVKANKRLEAVQHSRKYLGNFQQDDDYKTRRLGQAMLLLIMRTSEEVDAKAAQNELNEAWIIKRFHLALMNFYSFT-SPTPFSLAVRAGITAIKTHFCYNSKSRHPDCVVCHPLINRFAQNLLFGRYDHSVLTCYQTGLAMNDDNPPMALPNGYVYSQQREEEFDAESRSFAL 413
[Close]
BLAST of Macrophage erythroblast attacher vs. Ensembl Cavefish
Match: maea (macrophage erythroblast attacher [Source:NCBI gene;Acc:103034497])

HSP 1 Score: 118.242 bits (295), Expect = 8.072e-29
Identity = 106/413 (25.67%), Postives = 191/413 (46.25%), Query Frame = 1 
Query:   85 VKLTELTTLKASYEYLNKAYRGNQKSLEKDYQSMVKSIEDYKKANDA-----ENAQNCIGLFLENVSNLKRKAETIIAEELNYTKTCKIRLDHLLNLSVSKGNGNNQNCXXXXXXXXXXXXXXXXXSFLYEKGDNMQLKRMDNIDSTVRFQRHLADHLFAQGYCNTAVELAKSINIGENLEDNIGMIEIYQETLDIVEALKKGNFYPVEQWLQSIQFKYKKGDVKNSFESDLQIFKLYLLIKEGNWEKAIKFAHSFCDPKMINEDTMEKLSKVMTLVVFRS------YDELVAAARKWDVDEDWIVQRFHSFILQFYAFYHEPTVLSLMIKTGIAVRKTENCYKPN--MKRKECVVCTDRVNKISVDIPAARHDHSILVCWKTSLEMNEDNPPVAFPNGYVYSTKVWQEIRNN 1284
            +K+ E  TLK  YE LNK +R  QK+++++   +   + + +K   +     ++  + +   +E +S LKRKA   I  E    K CK R++HL      K + ++Q  ++                         + KRMD         R + +HL   GY NTAV+LA+   I    ED +  IE++    ++ E+L++        W    + + +K  +K+  E  L+I +   LI++     A++ A             ++++ +VM ++ F S      Y +L+   R W +    ++Q+F     + +   +  +V ++ ++ G++  KT  CYK +   K  +C VC+  +NK++  +P A   +S LVC  +   MNE+NPP+  PNGYVY       IR +
Sbjct:   14 LKVQEYPTLKVPYETLNKRFRAAQKNIDRETSHVTMVVAELEKTLSSSFPVVDSVVSLLDGVVEKLSALKRKAAESIQAEDESAKLCKRRIEHL------KEHSSDQPANVSV----------------------WKRKRMD---------RMMVEHLLRCGYYNTAVKLARQSGI----EDLVN-IEMFLTAKEVEESLERQETATCLAWCHDNKSRLRK--MKSCLEFSLRIQEFIELIRQNKRMDAVRHARKHFS--QAEGGQLDEVRQVMGMLAFPSDTHISPYKDLLDPGR-WKM----LIQQFRYDNYRLHQLGNN-SVFTITLQAGLSAIKTPQCYKEDGTSKNPDCPVCSKSLNKLAQPLPMAHCANSRLVCKISGEVMNENNPPMMLPNGYVYGYNSLLSIRQD 374
[Close]
BLAST of Macrophage erythroblast attacher vs. Ensembl Cavefish
Match: maea (macrophage erythroblast attacher [Source:NCBI gene;Acc:103034497])

HSP 1 Score: 97.0561 bits (240), Expect = 1.027e-21
Identity = 96/413 (23.24%), Postives = 172/413 (41.65%), Query Frame = 1 
Query:   85 VKLTELTTLKASYEYLNKAYRGNQKSLEKDYQSMVKSIEDYKKANDA-----ENAQNCIGLFLENVSNLKRKAETIIAEELNYTKTCKIRLDHLLNLSVSKGNGNNQNCXXXXXXXXXXXXXXXXXSFLYEKGDNMQLKRMDNIDSTVRFQRHLADHLFAQGYCNTAVELAKSINIGENLEDNIGMIEIYQETLDIVEALKKGNFYPVEQWLQSIQFKYKKGDVKNSFESDLQIFKLYLLIKEGNWEKAIKFAHSFCDPKMINEDTMEKLSKVMTLVVFRS------YDELVAAARKWDVDEDWIVQRFHSFILQFYAFYHEPTVLSLMIKTGIAVRKTENCYKPN--MKRKECVVCTDRVNKISVDIPAARHDHSILVCWKTSLEMNEDNPPVAFPNGYVYSTKVWQEIRNN 1284
            +K+ E  TLK  YE LNK +R  QK+++++   +   + + +K   +     ++  + +   +E +S LKRKA   I  E    K CK R++HL      K + ++Q  ++                         + KRMD         R + +HL   GY NTAV+LA+                                                +  +++  E  L+I +   LI++     A++ A             ++++ +VM ++ F S      Y +L+   R W +    ++Q+F     + +   +  +V ++ ++ G++  KT  CYK +   K  +C VC+  +NK++  +P A   +S LVC  +   MNE+NPP+  PNGYVY       IR +
Sbjct:   14 LKVQEYPTLKVPYETLNKRFRAAQKNIDRETSHVTMVVAELEKTLSSSFPVVDSVVSLLDGVVEKLSALKRKAAESIQAEDESAKLCKRRIEHL------KEHSSDQPANVSV----------------------WKRKRMD---------RMMVEHLLRCGYYNTAVKLAR------------------------------------------------QSGIESCLEFSLRIQEFIELIRQNKRMDAVRHARKHFS--QAEGGQLDEVRQVMGMLAFPSDTHISPYKDLLDPGR-WKM----LIQQFRYDNYRLHQLGNN-SVFTITLQAGLSAIKTPQCYKEDGTSKNPDCPVCSKSLNKLAQPLPMAHCANSRLVCKISGEVMNENNPPMMLPNGYVYGYNSLLSIRQD 333
[Close]
BLAST of Macrophage erythroblast attacher vs. Ensembl Nematostella
Match: EDO31713 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SX53])

HSP 1 Score: 123.25 bits (308), Expect = 4.475e-31
Identity = 106/404 (26.24%), Postives = 190/404 (47.03%), Query Frame = 1 
Query:   82 EVKLTELTTLKASYEYLNKAYRGNQKSLEKDYQSMVKSIEDY-----KKANDAENAQNCIGLFLENVSNLKRKAETIIAEELNYTKTCKIRLDHLLNLSVSKGNGNNQNCXXXXXXXXXXXXXXXXXSFLYEKGDNMQLKRMDNIDSTVRFQRHLADHLFAQGYCNTAVELAKSINIGENLEDNIGMIEIYQETLDIVEALKKGNFYPVEQWLQSIQFKYKKGDVKNSFESDLQIFKLYLLIKEGNWEKAIKFAHS-FCDPKMINEDTMEK-LSKVMTLVVFRS------YDELVAAARKWDVDEDWIVQRFHSFILQFYAFYHEPTVLSLMIKTGIAVRKTENCYKPNMKRKECVVCTDRVNKISVDIPAARHDHSILVCWKTSLEMNEDNPPVAFPNGYVYS 1254
            ++K  E +TLK  YE LNK +R  QK ++++   +V +  +      K A         +    + +  LKRK+E  I +E    K C+ RLDH+   +  + +                         +++K      KR+D         R L DH    G+  TA +LA+  +I    ED +  IE++  +  + E+L++ +  P   W    + K +K  +K++ E ++++ +   L+++G+  +A+++A   F +     E  M K + K M L+ F+       Y EL+  +R W      ++++F     Q +   +E +VLS+ ++ G++  KT +CY+   K  EC VC+  +N +   +P A    S LVC  +   MNE+NPP+  PNG+VY 
Sbjct:    3 DIKALEYSTLKVPYEVLNKKFRSAQKVIDREVSYVVGATNELTSTLSKPAVKTGEVTRMLDDIAQKIQVLKRKSEEYIGQEDVCVKHCRARLDHIKEHADPRKSA----------------------MVVWKK------KRLD---------RMLVDHCLRLGFYETAKKLAQDADI----EDFVD-IELFLVSRQVEESLQQEDSGPCLAWCYDNKSKLRK--LKSTLEFNVRMQEYVELVRKGDKLEAVRYARKHFAN----AESAMTKEIQKAMALLAFKPDKACSPYKELLEQSR-WT----HLIEQFRRENFQLHQL-NEQSVLSVTLQAGLSALKTPHCYQQGHKMPECPVCSHPMNILGQSLPFAHCAQSRLVCPISGQVMNENNPPMVLPNGFVYG 352
[Close]
BLAST of Macrophage erythroblast attacher vs. Ensembl Medaka
Match: maea (macrophage erythroblast attacher [Source:NCBI gene;Acc:101163665])

HSP 1 Score: 124.405 bits (311), Expect = 6.403e-31
Identity = 112/412 (27.18%), Postives = 190/412 (46.12%), Query Frame = 1 
Query:   85 VKLTELTTLKASYEYLNKAYRGNQKSLEKDYQSMVKSIEDYKKANDAENAQNCIGLFLENV----SNLKRKAETIIAEELNYTKTCKIRLDHLLNLSVSKGNGNNQNCXXXXXXXXXXXXXXXXXSFLYEKGDNMQLKRMDNIDSTVRFQRHLADHLFAQGYCNTAVELAKSINIGENLEDNIGMIEIYQETLDIVEALKKGNFYPVEQWLQSIQFKYKKGDVKNSFESDLQIFKLYLLIKEGNWEKAIKFAHSFCDPKMINEDTMEKLSKVMTLVVFRS------YDELVAAARKWDVDEDWIVQRFHSFILQFYAFYHEPTVLSLMIKTGIAVRKTENCYKPN--MKRKECVVCTDRVNKISVDIPAARHDHSILVCWKTSLEMNEDNPPVAFPNGYVYSTKVWQEIRNN 1284
            +K+ E  TLK  YE LNK +R  QK+++++   +   + + +K   +  A + +   L+ V    S LKRKA   I  E    K CK R++HL   S  +    N                      L++K      KRMD         R + +HL   GY NTAV+LAK   I    ED +  IE++    ++ E+L++        W    + + +K  +K+  E  L+I +   LI++     A++ A             ++++ +VM ++ F S      Y +L+  AR W +    ++Q+F     + +   +  +V ++ ++ G++  KT  CYK +   K  +C VC+  +NK++  +P A   +S LVC  +   MNE+NPP+  PNGYVY       IR +
Sbjct:   14 LKVQEYPTLKVPYETLNKRFRAAQKNIDREASHVTMVVAELEKTLSSFPAVDSVVSLLDGVVEKLSALKRKAAESIQAEDESAKLCKRRIEHLKEHSGDQPASVN----------------------LWKK------KRMD---------RMMVEHLLRCGYYNTAVKLAKQSGI----EDLVN-IEMFLTAKEVEESLERQETATCLAWCHDNKSRLRK--MKSCLEFSLRIQEFIELIRQNKRMDAVRHARKHFS--QAEGGQLDEVRQVMGMLAFPSDTHVSPYKDLLDPAR-WKM----LIQQFRYDNYRLHQLGNN-SVFTITLQAGLSAIKTPQCYKEDGSSKNPDCPVCSKSLNKLAQPLPMAHCANSRLVCKISGEVMNENNPPMMLPNGYVYGYNSLLSIRQD 373
[Close]
BLAST of Macrophage erythroblast attacher vs. Ensembl Medaka
Match: maea (macrophage erythroblast attacher [Source:NCBI gene;Acc:101163665])

HSP 1 Score: 103.219 bits (256), Expect = 7.542e-24
Identity = 102/412 (24.76%), Postives = 171/412 (41.50%), Query Frame = 1 
Query:   85 VKLTELTTLKASYEYLNKAYRGNQKSLEKDYQSMVKSIEDYKKANDAENAQNCIGLFLENV----SNLKRKAETIIAEELNYTKTCKIRLDHLLNLSVSKGNGNNQNCXXXXXXXXXXXXXXXXXSFLYEKGDNMQLKRMDNIDSTVRFQRHLADHLFAQGYCNTAVELAKSINIGENLEDNIGMIEIYQETLDIVEALKKGNFYPVEQWLQSIQFKYKKGDVKNSFESDLQIFKLYLLIKEGNWEKAIKFAHSFCDPKMINEDTMEKLSKVMTLVVFRS------YDELVAAARKWDVDEDWIVQRFHSFILQFYAFYHEPTVLSLMIKTGIAVRKTENCYKPN--MKRKECVVCTDRVNKISVDIPAARHDHSILVCWKTSLEMNEDNPPVAFPNGYVYSTKVWQEIRNN 1284
            +K+ E  TLK  YE LNK +R  QK+++++   +   + + +K   +  A + +   L+ V    S LKRKA   I  E    K CK R++HL   S  +    N                      L++K      KRMD         R + +HL   GY NTAV+LAK                                                +  +++  E  L+I +   LI++     A++ A             ++++ +VM ++ F S      Y +L+  AR W +    ++Q+F     + +   +  +V ++ ++ G++  KT  CYK +   K  +C VC+  +NK++  +P A   +S LVC  +   MNE+NPP+  PNGYVY       IR +
Sbjct:   14 LKVQEYPTLKVPYETLNKRFRAAQKNIDREASHVTMVVAELEKTLSSFPAVDSVVSLLDGVVEKLSALKRKAAESIQAEDESAKLCKRRIEHLKEHSGDQPASVN----------------------LWKK------KRMD---------RMMVEHLLRCGYYNTAVKLAK------------------------------------------------QSGIESCLEFSLRIQEFIELIRQNKRMDAVRHARKHFS--QAEGGQLDEVRQVMGMLAFPSDTHVSPYKDLLDPAR-WKM----LIQQFRYDNYRLHQLGNN-SVFTITLQAGLSAIKTPQCYKEDGSSKNPDCPVCSKSLNKLAQPLPMAHCANSRLVCKISGEVMNENNPPMMLPNGYVYGYNSLLSIRQD 332
[Close]
BLAST of Macrophage erythroblast attacher vs. Planmine SMEST
Match: SMESG000048410.1 (SMESG000048410.1)

HSP 1 Score: 787.334 bits (2032), Expect = 0.000e+0
Identity = 385/412 (93.45%), Postives = 387/412 (93.93%), Query Frame = 1 
Query:   40 MADKQIYVNSDCQDEVKLTELTTLKASYEYLNKAYRGNQKSLEKDYQSMVKSIEDYKKANDAENAQNCIGLFLENVSNLKRKAETIIAEELNYTKTCKIRLDHLLNLSVSKGNGNNQNCXXXXXXXXXXXXXXXXXSFLYEKGDNMQLKRMDNIDSTVRFQRHLADHLFAQGYCNTAVELAKSINIGENLEDNIGMIEIYQETLDIVEALKKGNFYPVEQWLQSIQFKYKKGDVKNSFESDLQIFKLYLLIKEGNWEKAIKFAHSFCDPKMINEDTMEKLSKVMTLVVFRSYDELVAAARKWDVDEDWIVQRFHSFILQFYAFYHEPTVLSLMIKTGIAVRKTENCYKPNMKRKECVVCTDRVNKISVDIPAARHDHSILVCWKTSLEMNEDNPPVAFPNGYVYSTKVWQEI 1275
            MADKQIYVNSDCQDEVKLTELTTLKASYEYLNKAYRGNQKSLEKDYQSMVKSIEDYKKANDAENAQNCIGLFLENVSNLKRKAETIIAEELNYTKTCKIRLDHLLNLSVSKGN +                     SFLYEKGDNMQLKRMDNIDSTVRFQRHLADHLFAQGYCNTAVELAKSINIGENLEDNIGMIEIYQETLDIVEALKKGNFYPVEQWLQSIQFKYKKGDVKNSFESDLQIFKLYLLIKEGNWEKAIKFAHSFCDPKMINEDTMEKLSKVMTLVVFRSYDELVAAARKWDVDEDWIVQRFHSFILQFYAFYHEPTVLSLMIKTGIAVRKTENCYKPNMKRKECVVCTDRVNKISVDIPAARHDHSILVCWKTSLEMNEDNPPVAFPNGYVYSTK   E+
Sbjct:    1 MADKQIYVNSDCQDEVKLTELTTLKASYEYLNKAYRGNQKSLEKDYQSMVKSIEDYKKANDAENAQNCIGLFLENVSNLKRKAETIIAEELNYTKTCKIRLDHLLNLSVSKGNDS---------------------SFLYEKGDNMQLKRMDNIDSTVRFQRHLADHLFAQGYCNTAVELAKSINIGENLEDNIGMIEIYQETLDIVEALKKGNFYPVEQWLQSIQFKYKKGDVKNSFESDLQIFKLYLLIKEGNWEKAIKFAHSFCDPKMINEDTMEKLSKVMTLVVFRSYDELVAAARKWDVDEDWIVQRFHSFILQFYAFYHEPTVLSLMIKTGIAVRKTENCYKPNMKRKECVVCTDRVNKISVDIPAARHDHSILVCWKTSLEMNEDNPPVAFPNGYVYSTKAIPEM 391

HSP 2 Score: 77.411 bits (189), Expect = 4.126e-15
Identity = 37/44 (84.09%), Postives = 39/44 (88.64%), Query Frame = 3 
Query: 1287 GYVCTDNFSLQAIPEMLDPTDNKIVCPRSGFRCKESELQKVYIV 1418
            GYV    +S +AIPEMLDPTDNKIVCPRSGFRCKESELQKVYIV
Sbjct:  380 GYV----YSTKAIPEMLDPTDNKIVCPRSGFRCKESELQKVYIV 419
The following BLAST results are available for this feature:
BLAST of Macrophage erythroblast attacher vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
MAEA3.502e-2826.21macrophage erythroblast attacher [Source:HGNC Symb... [more]
MAEA2.850e-2625.78macrophage erythroblast attacher [Source:HGNC Symb... [more]
MAEA2.897e-2324.33macrophage erythroblast attacher [Source:HGNC Symb... [more]
MAEA9.546e-2226.50macrophage erythroblast attacher [Source:HGNC Symb... [more]
MAEA3.313e-2123.79macrophage erythroblast attacher [Source:HGNC Symb... [more]
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BLAST of Macrophage erythroblast attacher vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 1
Match NameE-valueIdentityDescription
maea-17.079e-1321.22MAEA (MAcrophage Erythroblast Attacher protein) ho... [more]
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BLAST of Macrophage erythroblast attacher vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 1
Match NameE-valueIdentityDescription
CG313573.342e-2824.24gene:FBgn0051357 transcript:FBtr0084735[more]
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BLAST of Macrophage erythroblast attacher vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 1
Match NameE-valueIdentityDescription
maea1.179e-2926.21macrophage erythroblast attacher [Source:NCBI gene... [more]
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BLAST of Macrophage erythroblast attacher vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 2
Match NameE-valueIdentityDescription
maea1.995e-2726.12macrophage erythroblast attacher [Source:NCBI gene... [more]
maea1.417e-2525.57macrophage erythroblast attacher [Source:NCBI gene... [more]
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BLAST of Macrophage erythroblast attacher vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 2
Match NameE-valueIdentityDescription
Maea4.518e-2926.46macrophage erythroblast attacher [Source:MGI Symbo... [more]
Maea2.174e-727.43macrophage erythroblast attacher [Source:MGI Symbo... [more]
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BLAST of Macrophage erythroblast attacher vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q5F398|MAEA_CHICK3.448e-2926.70E3 ubiquitin-protein transferase MAEA OS=Gallus ga... [more]
sp|Q6GR10|MAEA_XENLA5.733e-2926.70E3 ubiquitin-protein transferase MAEA OS=Xenopus l... [more]
sp|Q7SXR3|MAEA_DANRE8.898e-2926.21E3 ubiquitin-protein transferase MAEA OS=Danio rer... [more]
sp|Q5RKJ1|MAEA_RAT3.160e-2826.46E3 ubiquitin-protein transferase MAEA OS=Rattus no... [more]
sp|Q4VC33|MAEA_MOUSE3.160e-2826.46E3 ubiquitin-protein transferase MAEA OS=Mus muscu... [more]
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BLAST of Macrophage erythroblast attacher vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
G4V5H07.082e-7736.88Putative erythroblast macrophage protein emp OS=Sc... [more]
A0A3Q0KC392.640e-7636.52Putative erythroblast macrophage protein emp OS=Sc... [more]
A0A4Z2DDB01.747e-7435.94Macrophage erythroblast attacher OS=Schistosoma ja... [more]
A0A430QFP22.681e-7235.38Macrophage erythroblast attacher OS=Schistosoma bo... [more]
A0A0R3X4B71.206e-7133.57CTLH domain-containing protein OS=Hydatigena taeni... [more]
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BLAST of Macrophage erythroblast attacher vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 2
Match NameE-valueIdentityDescription
maea8.072e-2925.67macrophage erythroblast attacher [Source:NCBI gene... [more]
maea1.027e-2123.24macrophage erythroblast attacher [Source:NCBI gene... [more]
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BLAST of Macrophage erythroblast attacher vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Macrophage erythroblast attacher vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Macrophage erythroblast attacher vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1
Match NameE-valueIdentityDescription
EDO317134.475e-3126.24Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Macrophage erythroblast attacher vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 2
Match NameE-valueIdentityDescription
maea6.403e-3127.18macrophage erythroblast attacher [Source:NCBI gene... [more]
maea7.542e-2424.76macrophage erythroblast attacher [Source:NCBI gene... [more]
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BLAST of Macrophage erythroblast attacher vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 1
Match NameE-valueIdentityDescription
SMESG000048410.14.126e-1593.45SMESG000048410.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30009887 ID=SMED30009887|Name=Macrophage erythroblast attacher|organism=Schmidtea mediterranea sexual|type=transcript|length=1477bp
AGAAAAGCAGTTAAAATTTATCAGCTGATAAATTTTTAAATGGCAGATAA
ACAAATATATGTTAATTCTGATTGCCAAGATGAAGTTAAATTGACAGAAT
TAACAACTCTTAAAGCGAGTTATGAGTACTTAAATAAAGCTTATCGGGGC
AATCAAAAATCTTTGGAAAAAGATTATCAATCAATGGTTAAATCAATAGA
AGATTACAAAAAAGCGAATGATGCTGAAAACGCTCAAAATTGCATTGGTT
TGTTTTTAGAGAACGTATCGAACTTAAAACGGAAGGCTGAAACGATAATC
GCAGAGGAGCTAAATTATACCAAAACCTGTAAGATCAGATTAGATCATTT
ATTAAATTTGTCTGTCAGTAAAGGAAACGGTAATAATCAGAATTGTGATC
TTGAACCATTTTCATTATTATTATTATATTTCCTGCGACCAGATTCAAGT
TTCCTATATGAGAAAGGCGACAATATGCAACTAAAACGAATGGATAATAT
TGATTCAACCGTTAGGTTTCAGCGGCATTTAGCTGATCATTTGTTTGCTC
AAGGTTATTGTAACACTGCCGTTGAGTTAGCCAAATCAATTAATATCGGC
GAGAATCTCGAAGACAATATCGGGATGATAGAAATTTATCAAGAAACCCT
AGACATTGTGGAAGCATTAAAAAAAGGAAATTTTTACCCAGTTGAGCAAT
GGCTTCAATCGATTCAGTTCAAATATAAAAAAGGCGATGTCAAAAATTCA
TTCGAAAGCGACCTACAGATCTTCAAGCTCTATTTGTTGATCAAAGAAGG
CAATTGGGAAAAGGCAATTAAATTTGCTCATTCGTTTTGCGACCCGAAGA
TGATTAATGAGGACACAATGGAGAAGCTAAGCAAGGTTATGACGCTGGTG
GTATTTCGATCATATGATGAACTAGTAGCTGCTGCACGTAAATGGGATGT
CGATGAAGATTGGATTGTTCAAAGATTCCATTCATTTATTTTACAGTTCT
ATGCATTTTATCACGAACCTACAGTTTTGTCATTGATGATCAAGACCGGC
ATAGCTGTCAGAAAGACTGAGAATTGCTACAAACCGAACATGAAGAGAAA
AGAGTGCGTGGTATGCACAGATCGAGTGAATAAAATTTCCGTGGATATCC
CCGCCGCTAGACATGACCATTCGATTCTCGTTTGCTGGAAAACAAGTCTA
GAAATGAACGAAGACAACCCTCCAGTTGCATTTCCCAATGGGTATGTTTA
CAGCACAAAGGTTTGGCAGGAAATTAGGAATAATTCGGTTACGTTTGCAC
TGATAATTTCTCATTGCAGGCAATTCCCGAAATGCTCGACCCAACTGACA
ACAAAATTGTTTGTCCGAGATCAGGATTCAGGTGTAAAGAAAGCGAATTG
CAAAAGGTTTATATTGTTTGATGTTCTCTGTGTTGATGGCCTATTTTTGT
TTGAATAAAATGATTCTGTTAAAAAAA
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protein sequence of SMED30009887-orf-1

>SMED30009887-orf-1 ID=SMED30009887-orf-1|Name=SMED30009887-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=473bp
MADKQIYVNSDCQDEVKLTELTTLKASYEYLNKAYRGNQKSLEKDYQSMV
KSIEDYKKANDAENAQNCIGLFLENVSNLKRKAETIIAEELNYTKTCKIR
LDHLLNLSVSKGNGNNQNCDLEPFSLLLLYFLRPDSSFLYEKGDNMQLKR
MDNIDSTVRFQRHLADHLFAQGYCNTAVELAKSINIGENLEDNIGMIEIY
QETLDIVEALKKGNFYPVEQWLQSIQFKYKKGDVKNSFESDLQIFKLYLL
IKEGNWEKAIKFAHSFCDPKMINEDTMEKLSKVMTLVVFRSYDELVAAAR
KWDVDEDWIVQRFHSFILQFYAFYHEPTVLSLMIKTGIAVRKTENCYKPN
MKRKECVVCTDRVNKISVDIPAARHDHSILVCWKTSLEMNEDNPPVAFPN
GYVYSTKVWQEIRNNSVTFALIISHCRQFPKCSTQLTTKLFVRDQDSGVK
KANCKRFILFDVLCVDGLFLFE*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000016pharynx
PLANA:0000034epidermis
PLANA:0000099neuron
PLANA:0000429neoblast
Vocabulary: INTERPRO
TermDefinition
IPR027714Fyv10/EMP
IPR024964CTLH/CRA
Vocabulary: biological process
TermDefinition
GO:0045721negative regulation of gluconeogenesis
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR024964CTLH/CRA C-terminal to LisH motif domainPFAMPF10607CLTHcoord: 201..321
e-value: 8.6E-7
score: 29.0
NoneNo IPR availablePANTHERPTHR12170MACROPHAGE ERYTHROBLAST ATTACHER-RELATEDcoord: 13..419
NoneNo IPR availablePROSITEPS51867ZF_RING_GIDcoord: 356..432
score: 9.434
IPR027714Protein Fyv10/Macrophage erythroblast attacherPANTHERPTHR12170:SF2MACROPHAGE ERYTHROBLAST ATTACHERcoord: 13..419