apaf1

Overview
Nameapaf1 (AEX93473.1)
Smed IDSMED30009849
Length (bp)2446
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of apaf1 (SMED30009849) t-SNE clustered cells

Violin plots show distribution of expression levels for apaf1 (SMED30009849) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of apaf1 (SMED30009849) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for apaf1 (SMED30009849) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30009849

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 3

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
epidermisSMED30009849h1SMcG0011546 dd_Smed_v4_3375_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30009849h1SMcG0011546 dd_Smed_v4_3375_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30009849h1SMcG0011546 dd_Smed_v4_3375_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017		whole organism asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of apaf1 vs. Ensembl Human
Match: APAF1 (apoptotic peptidase activating factor 1 [Source:HGNC Symbol;Acc:HGNC:576])

HSP 1 Score: 85.8853 bits (211), Expect = 1.810e-16
Identity = 156/672 (23.21%), Postives = 286/672 (42.56%), Query Frame = 3 
Query:  129 DILEDVIPTDIIPD-LRSCKLFTLEDEQIVLHEITDKAKNRKLLDIIKSRPDELYEKFC-EILRITNEDVAENLESHDYTRTRRVSNTDFGDILIKGGVPDRNVDYVPRPNLENIILNAIISNKKMP--ILIHGIIGCGKTSIVSNLLHSDQLFPYRFLTCC-WMDVGNIEEKDIXXXXXXXXXXXDP----SPQLPLNIIPEILVDRIK-AKLYDGTTXXXXXXXXXXXXXXXXXXXXTYIVVSRQSNLVPDST---------AKLINIPDGFEIEECRSLMKHYNISEDLFPKIISKSMKNPLSLSMICKLVH-------------SNGDYIRMLNEKSFNSNHLDKIVQGYIKVLDDELKSKYEMLAIXXXXXXXXXXXXXYYWNVSYVKALDMVNKLCDFNLLHKTWNS-TFNINLYGVYDIYLKYL-QQNVTNLQKFKQIFIDNYEAKYKKWLDVKEPDPFFLIFYGKTLFYN----KNDEKLIELYTDFSFIAAKIVICGIIYLQNEYEKYKPSDFNSDW---DDFEAFFIKYSHKFMKIPSACKIPTKIGKVFINLIQLALYEPKTSATYKFA-MSCKNKC-NWKDFWEWTNPRNSIKVWEI---NHGDNI--TSFDVMKNLIIMSSDSNSMRLLEFSTGKCLLNFKLR-NHILLVKFISDHEFI 1997
            + LE  I T  I D + S    T+ +E+ V +E T + +   L+ +I  + ++ Y  F   +L    +D+A  L       +     T    +L +GGVP R V +V R  L N I   +   K  P  + IHG+ GCGK+ + +  +    L    F     W+ VG  ++  +  KL +L  +LD     S +LPLNI  E   DR++   L      L++ +   ++ +         I+++ +   V DS             +    G EI      MK  ++ E     II +   +PL +S+I  L+               N  + R+    S++   LD+ +   +++L +++K  Y  L+IL+ D  +  ++L   W++   +  D++ +  + +LL    N  +F    Y ++D+ + +L ++N + LQ   +  I  ++  ++       PD    +++   L Y+    K  ++L  L     +I AK  + G  +L +E+ +Y+      D    ++F+ F     H   + P            F N++QL L EP+TS  Y+ A +  K +  N   + EW N +N   +  +    H D +    F      I       ++++ +  TG+ LL  K   + +L   F +D  FI
Sbjct:   14 EALEKDIKTSYIMDHMISDGFLTISEEEKVRNEPTQQQRAAMLIKMILKKDNDSYVSFYNALLHEGYKDLAALLHDGIPVVSSSSVRT----VLCEGGVPQRPVVFVTRKKLVNAIQQKLSKLKGEPGWVTIHGMAGCGKSVLAAEAVRDHSLLEGCFPGGVHWVSVGKQDKSGLLMKLQNLCTRLDQDESFSQRLPLNI--EEAKDRLRILMLRKHPRSLLILDDVWDSWVLKAFDSQCQILLTTRDKSVTDSVMGPKYVVPVESSLGKEKGLEILSLFVNMKKADLPEQAHS-IIKECKGSPLVVSLIGALLRDFPNRWEYYLKQLQNKQFKRIRKSSSYDYEALDEAMSISVEMLREDIKDYYTDLSILQKDVKVPTKVLCILWDMETEEVEDILQEFVNKSLLFCDRNGKSFR---YYLHDLQVDFLTEKNCSQLQDLHKKIITQFQRYHQP--HTLSPDQEDCMYWYNFLAYHMASAKMHKELCALMFSLDWIKAKTELVGPAHLIHEFVEYRHILDEKDCAVSENFQEFLSLNGHLLGRQP------------FPNIVQLGLCEPETSEVYQQAKLQAKQEVDNGMLYLEWINKKNITNLSRLVVRPHTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSTDDRFI 661
[Close]
BLAST of apaf1 vs. Ensembl Human
Match: APAF1 (apoptotic peptidase activating factor 1 [Source:HGNC Symbol;Acc:HGNC:576])

HSP 1 Score: 85.8853 bits (211), Expect = 2.071e-16
Identity = 156/672 (23.21%), Postives = 286/672 (42.56%), Query Frame = 3 
Query:  129 DILEDVIPTDIIPD-LRSCKLFTLEDEQIVLHEITDKAKNRKLLDIIKSRPDELYEKFC-EILRITNEDVAENLESHDYTRTRRVSNTDFGDILIKGGVPDRNVDYVPRPNLENIILNAIISNKKMP--ILIHGIIGCGKTSIVSNLLHSDQLFPYRFLTCC-WMDVGNIEEKDIXXXXXXXXXXXDP----SPQLPLNIIPEILVDRIK-AKLYDGTTXXXXXXXXXXXXXXXXXXXXTYIVVSRQSNLVPDST---------AKLINIPDGFEIEECRSLMKHYNISEDLFPKIISKSMKNPLSLSMICKLVH-------------SNGDYIRMLNEKSFNSNHLDKIVQGYIKVLDDELKSKYEMLAIXXXXXXXXXXXXXYYWNVSYVKALDMVNKLCDFNLLHKTWNS-TFNINLYGVYDIYLKYL-QQNVTNLQKFKQIFIDNYEAKYKKWLDVKEPDPFFLIFYGKTLFYN----KNDEKLIELYTDFSFIAAKIVICGIIYLQNEYEKYKPSDFNSDW---DDFEAFFIKYSHKFMKIPSACKIPTKIGKVFINLIQLALYEPKTSATYKFA-MSCKNKC-NWKDFWEWTNPRNSIKVWEI---NHGDNI--TSFDVMKNLIIMSSDSNSMRLLEFSTGKCLLNFKLR-NHILLVKFISDHEFI 1997
            + LE  I T  I D + S    T+ +E+ V +E T + +   L+ +I  + ++ Y  F   +L    +D+A  L       +     T    +L +GGVP R V +V R  L N I   +   K  P  + IHG+ GCGK+ + +  +    L    F     W+ VG  ++  +  KL +L  +LD     S +LPLNI  E   DR++   L      L++ +   ++ +         I+++ +   V DS             +    G EI      MK  ++ E     II +   +PL +S+I  L+               N  + R+    S++   LD+ +   +++L +++K  Y  L+IL+ D  +  ++L   W++   +  D++ +  + +LL    N  +F    Y ++D+ + +L ++N + LQ   +  I  ++  ++       PD    +++   L Y+    K  ++L  L     +I AK  + G  +L +E+ +Y+      D    ++F+ F     H   + P            F N++QL L EP+TS  Y+ A +  K +  N   + EW N +N   +  +    H D +    F      I       ++++ +  TG+ LL  K   + +L   F +D  FI
Sbjct:   14 EALEKDIKTSYIMDHMISDGFLTISEEEKVRNEPTQQQRAAMLIKMILKKDNDSYVSFYNALLHEGYKDLAALLHDGIPVVSSSSVRT----VLCEGGVPQRPVVFVTRKKLVNAIQQKLSKLKGEPGWVTIHGMAGCGKSVLAAEAVRDHSLLEGCFPGGVHWVSVGKQDKSGLLMKLQNLCTRLDQDESFSQRLPLNI--EEAKDRLRILMLRKHPRSLLILDDVWDSWVLKAFDSQCQILLTTRDKSVTDSVMGPKYVVPVESSLGKEKGLEILSLFVNMKKADLPEQAHS-IIKECKGSPLVVSLIGALLRDFPNRWEYYLKQLQNKQFKRIRKSSSYDYEALDEAMSISVEMLREDIKDYYTDLSILQKDVKVPTKVLCILWDMETEEVEDILQEFVNKSLLFCDRNGKSFR---YYLHDLQVDFLTEKNCSQLQDLHKKIITQFQRYHQP--HTLSPDQEDCMYWYNFLAYHMASAKMHKELCALMFSLDWIKAKTELVGPAHLIHEFVEYRHILDEKDCAVSENFQEFLSLNGHLLGRQP------------FPNIVQLGLCEPETSEVYQQAKLQAKQEVDNGMLYLEWINKKNITNLSRLVVRPHTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSTDDRFI 661
[Close]
BLAST of apaf1 vs. Ensembl Human
Match: APAF1 (apoptotic peptidase activating factor 1 [Source:HGNC Symbol;Acc:HGNC:576])

HSP 1 Score: 83.5741 bits (205), Expect = 1.163e-15
Identity = 160/691 (23.15%), Postives = 289/691 (41.82%), Query Frame = 3 
Query:  129 DILEDVIPTDIIPD-LRSCKLFTLEDEQIVLHEITDKAKNRKLLDIIKSRPDELYEKFC-EILRITNEDVAENLESHD-------------------YTRTRRVSNTDFGDILIKGGVPDRNVDYVPRPNLENIILNAIISNKKMP--ILIHGIIGCGKTSIVSNLLHSDQLFPYRFLTCC-WMDVGNIEEKDIXXXXXXXXXXXDP----SPQLPLNIIPEILVDRIK-AKLYDGTTXXXXXXXXXXXXXXXXXXXXTYIVVSRQSNLVPDST---------AKLINIPDGFEIEECRSLMKHYNISEDLFPKIISKSMKNPLSLSMICKLVH-------------SNGDYIRMLNEKSFNSNHLDKIVQGYIKVLDDELKSKYEMLAIXXXXXXXXXXXXXYYWNVSYVKALDMVNKLCDFNLLHKTWNS-TFNINLYGVYDIYLKYL-QQNVTNLQKFKQIFIDNYEAKYKKWLDVKEPDPFFLIFYGKTLFYN----KNDEKLIELYTDFSFIAAKIVICGIIYLQNEYEKYKPSDFNSDW---DDFEAFFIKYSHKFMKIPSACKIPTKIGKVFINLIQLALYEPKTSATYKFA-MSCKNKC-NWKDFWEWTNPRNSIKVWEI---NHGDNI--TSFDVMKNLIIMSSDSNSMRLLEFSTGKCLLNFKLR-NHILLVKFISDHEFI 1997
            + LE  I T  I D + S    T+ +E+ V +E T + +   L+ +I  + ++ Y  F   +L    +D+A  L  HD                   Y RT          +L +GGVP R V +V R  L N I   +   K  P  + IHG+ GCGK+ + +  +    L    F     W+ VG  ++  +  KL +L  +LD     S +LPLNI  E   DR++   L      L++ +   ++ +         I+++ +   V DS             +    G EI      MK  ++ E     II +   +PL +S+I  L+               N  + R+    S++   LD+ +   +++L +++K  Y  L+IL+ D  +  ++L   W++   +  D++ +  + +LL    N  +F    Y ++D+ + +L ++N + LQ   +  I  ++  ++       PD    +++   L Y+    K  ++L  L     +I AK  + G  +L +E+ +Y+      D    ++F+ F     H   + P            F N++QL L EP+TS  Y+ A +  K +  N   + EW N +N   +  +    H D +    F      I       ++++ +  TG+ LL  K   + +L   F +D  FI
Sbjct:   14 EALEKDIKTSYIMDHMISDGFLTISEEEKVRNEPTQQQRAAMLIKMILKKDNDSYVSFYNALLHEGYKDLAALL--HDGIPVVSSSSGKDSVSGITSYVRT----------VLCEGGVPQRPVVFVTRKKLVNAIQQKLSKLKGEPGWVTIHGMAGCGKSVLAAEAVRDHSLLEGCFPGGVHWVSVGKQDKSGLLMKLQNLCTRLDQDESFSQRLPLNI--EEAKDRLRILMLRKHPRSLLILDDVWDSWVLKAFDSQCQILLTTRDKSVTDSVMGPKYVVPVESSLGKEKGLEILSLFVNMKKADLPEQAHS-IIKECKGSPLVVSLIGALLRDFPNRWEYYLKQLQNKQFKRIRKSSSYDYEALDEAMSISVEMLREDIKDYYTDLSILQKDVKVPTKVLCILWDMETEEVEDILQEFVNKSLLFCDRNGKSFR---YYLHDLQVDFLTEKNCSQLQDLHKKIITQFQRYHQP--HTLSPDQEDCMYWYNFLAYHMASAKMHKELCALMFSLDWIKAKTELVGPAHLIHEFVEYRHILDEKDCAVSENFQEFLSLNGHLLGRQP------------FPNIVQLGLCEPETSEVYQQAKLQAKQEVDNGMLYLEWINKKNITNLSRLVVRPHTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSTDDRFI 672
[Close]
BLAST of apaf1 vs. Ensembl Human
Match: APAF1 (apoptotic peptidase activating factor 1 [Source:HGNC Symbol;Acc:HGNC:576])

HSP 1 Score: 83.1889 bits (204), Expect = 1.263e-15
Identity = 160/691 (23.15%), Postives = 289/691 (41.82%), Query Frame = 3 
Query:  129 DILEDVIPTDIIPD-LRSCKLFTLEDEQIVLHEITDKAKNRKLLDIIKSRPDELYEKFC-EILRITNEDVAENLESHD-------------------YTRTRRVSNTDFGDILIKGGVPDRNVDYVPRPNLENIILNAIISNKKMP--ILIHGIIGCGKTSIVSNLLHSDQLFPYRFLTCC-WMDVGNIEEKDIXXXXXXXXXXXDP----SPQLPLNIIPEILVDRIK-AKLYDGTTXXXXXXXXXXXXXXXXXXXXTYIVVSRQSNLVPDST---------AKLINIPDGFEIEECRSLMKHYNISEDLFPKIISKSMKNPLSLSMICKLVH-------------SNGDYIRMLNEKSFNSNHLDKIVQGYIKVLDDELKSKYEMLAIXXXXXXXXXXXXXYYWNVSYVKALDMVNKLCDFNLLHKTWNS-TFNINLYGVYDIYLKYL-QQNVTNLQKFKQIFIDNYEAKYKKWLDVKEPDPFFLIFYGKTLFYN----KNDEKLIELYTDFSFIAAKIVICGIIYLQNEYEKYKPSDFNSDW---DDFEAFFIKYSHKFMKIPSACKIPTKIGKVFINLIQLALYEPKTSATYKFA-MSCKNKC-NWKDFWEWTNPRNSIKVWEI---NHGDNI--TSFDVMKNLIIMSSDSNSMRLLEFSTGKCLLNFKLR-NHILLVKFISDHEFI 1997
            + LE  I T  I D + S    T+ +E+ V +E T + +   L+ +I  + ++ Y  F   +L    +D+A  L  HD                   Y RT          +L +GGVP R V +V R  L N I   +   K  P  + IHG+ GCGK+ + +  +    L    F     W+ VG  ++  +  KL +L  +LD     S +LPLNI  E   DR++   L      L++ +   ++ +         I+++ +   V DS             +    G EI      MK  ++ E     II +   +PL +S+I  L+               N  + R+    S++   LD+ +   +++L +++K  Y  L+IL+ D  +  ++L   W++   +  D++ +  + +LL    N  +F    Y ++D+ + +L ++N + LQ   +  I  ++  ++       PD    +++   L Y+    K  ++L  L     +I AK  + G  +L +E+ +Y+      D    ++F+ F     H   + P            F N++QL L EP+TS  Y+ A +  K +  N   + EW N +N   +  +    H D +    F      I       ++++ +  TG+ LL  K   + +L   F +D  FI
Sbjct:   14 EALEKDIKTSYIMDHMISDGFLTISEEEKVRNEPTQQQRAAMLIKMILKKDNDSYVSFYNALLHEGYKDLAALL--HDGIPVVSSSSGKDSVSGITSYVRT----------VLCEGGVPQRPVVFVTRKKLVNAIQQKLSKLKGEPGWVTIHGMAGCGKSVLAAEAVRDHSLLEGCFPGGVHWVSVGKQDKSGLLMKLQNLCTRLDQDESFSQRLPLNI--EEAKDRLRILMLRKHPRSLLILDDVWDSWVLKAFDSQCQILLTTRDKSVTDSVMGPKYVVPVESSLGKEKGLEILSLFVNMKKADLPEQAHS-IIKECKGSPLVVSLIGALLRDFPNRWEYYLKQLQNKQFKRIRKSSSYDYEALDEAMSISVEMLREDIKDYYTDLSILQKDVKVPTKVLCILWDMETEEVEDILQEFVNKSLLFCDRNGKSFR---YYLHDLQVDFLTEKNCSQLQDLHKKIITQFQRYHQP--HTLSPDQEDCMYWYNFLAYHMASAKMHKELCALMFSLDWIKAKTELVGPAHLIHEFVEYRHILDEKDCAVSENFQEFLSLNGHLLGRQP------------FPNIVQLGLCEPETSEVYQQAKLQAKQEVDNGMLYLEWINKKNITNLSRLVVRPHTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSTDDRFI 672
[Close]
BLAST of apaf1 vs. Ensembl Human
Match: APAF1 (apoptotic peptidase activating factor 1 [Source:HGNC Symbol;Acc:HGNC:576])

HSP 1 Score: 83.1889 bits (204), Expect = 1.263e-15
Identity = 160/691 (23.15%), Postives = 289/691 (41.82%), Query Frame = 3 
Query:  129 DILEDVIPTDIIPD-LRSCKLFTLEDEQIVLHEITDKAKNRKLLDIIKSRPDELYEKFC-EILRITNEDVAENLESHD-------------------YTRTRRVSNTDFGDILIKGGVPDRNVDYVPRPNLENIILNAIISNKKMP--ILIHGIIGCGKTSIVSNLLHSDQLFPYRFLTCC-WMDVGNIEEKDIXXXXXXXXXXXDP----SPQLPLNIIPEILVDRIK-AKLYDGTTXXXXXXXXXXXXXXXXXXXXTYIVVSRQSNLVPDST---------AKLINIPDGFEIEECRSLMKHYNISEDLFPKIISKSMKNPLSLSMICKLVH-------------SNGDYIRMLNEKSFNSNHLDKIVQGYIKVLDDELKSKYEMLAIXXXXXXXXXXXXXYYWNVSYVKALDMVNKLCDFNLLHKTWNS-TFNINLYGVYDIYLKYL-QQNVTNLQKFKQIFIDNYEAKYKKWLDVKEPDPFFLIFYGKTLFYN----KNDEKLIELYTDFSFIAAKIVICGIIYLQNEYEKYKPSDFNSDW---DDFEAFFIKYSHKFMKIPSACKIPTKIGKVFINLIQLALYEPKTSATYKFA-MSCKNKC-NWKDFWEWTNPRNSIKVWEI---NHGDNI--TSFDVMKNLIIMSSDSNSMRLLEFSTGKCLLNFKLR-NHILLVKFISDHEFI 1997
            + LE  I T  I D + S    T+ +E+ V +E T + +   L+ +I  + ++ Y  F   +L    +D+A  L  HD                   Y RT          +L +GGVP R V +V R  L N I   +   K  P  + IHG+ GCGK+ + +  +    L    F     W+ VG  ++  +  KL +L  +LD     S +LPLNI  E   DR++   L      L++ +   ++ +         I+++ +   V DS             +    G EI      MK  ++ E     II +   +PL +S+I  L+               N  + R+    S++   LD+ +   +++L +++K  Y  L+IL+ D  +  ++L   W++   +  D++ +  + +LL    N  +F    Y ++D+ + +L ++N + LQ   +  I  ++  ++       PD    +++   L Y+    K  ++L  L     +I AK  + G  +L +E+ +Y+      D    ++F+ F     H   + P            F N++QL L EP+TS  Y+ A +  K +  N   + EW N +N   +  +    H D +    F      I       ++++ +  TG+ LL  K   + +L   F +D  FI
Sbjct:   14 EALEKDIKTSYIMDHMISDGFLTISEEEKVRNEPTQQQRAAMLIKMILKKDNDSYVSFYNALLHEGYKDLAALL--HDGIPVVSSSSGKDSVSGITSYVRT----------VLCEGGVPQRPVVFVTRKKLVNAIQQKLSKLKGEPGWVTIHGMAGCGKSVLAAEAVRDHSLLEGCFPGGVHWVSVGKQDKSGLLMKLQNLCTRLDQDESFSQRLPLNI--EEAKDRLRILMLRKHPRSLLILDDVWDSWVLKAFDSQCQILLTTRDKSVTDSVMGPKYVVPVESSLGKEKGLEILSLFVNMKKADLPEQAHS-IIKECKGSPLVVSLIGALLRDFPNRWEYYLKQLQNKQFKRIRKSSSYDYEALDEAMSISVEMLREDIKDYYTDLSILQKDVKVPTKVLCILWDMETEEVEDILQEFVNKSLLFCDRNGKSFR---YYLHDLQVDFLTEKNCSQLQDLHKKIITQFQRYHQP--HTLSPDQEDCMYWYNFLAYHMASAKMHKELCALMFSLDWIKAKTELVGPAHLIHEFVEYRHILDEKDCAVSENFQEFLSLNGHLLGRQP------------FPNIVQLGLCEPETSEVYQQAKLQAKQEVDNGMLYLEWINKKNITNLSRLVVRPHTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSTDDRFI 672
[Close]
BLAST of apaf1 vs. Ensembl Zebrafish
Match: apaf1 (apoptotic peptidase activating factor 1 [Source:NCBI gene;Acc:58131])

HSP 1 Score: 51.6026 bits (122), Expect = 3.180e-6
Identity = 86/390 (22.05%), Postives = 164/390 (42.05%), Query Frame = 3 
Query:   90 NTEYLRALAYNEDDILEDVIPTDIIPDLRSCKLFTLEDEQIVLHEITDKAKNRKLLDIIKSRPDELYEKFC-EILRITNEDVAENLESHDYTRTRRVSNTDFGD--------ILIKGGVPDRNVDYVPRPNLENIILNAIISNKKMP--ILIHGIIGCGKTSIVSNLLHSDQLFPYRFLTCC-WMDVGNIEEKDIXXXXXXXXXXXDPSPQLPLNIIPEILVDRIKAKLYDGTTXXXXXXXXXXXXXXXXXXXXTY-----IVVSRQSNLVPDSTAKL---INIPDGFEIEECRSLMKHY-NISEDLFPK----IISKSMKNPLSLSMICKLVHSNGD----YIRMLNEKSFNS---------NHLDKIVQGYIKVLDDELKSKYEMLAI 1145
             +  LR+ A  E DI    +   +I D     + T ++E  VL + T K +   LL+ +  + +  Y  F   ++R +  D+A  L S D           F D        IL  GGVP R V +V RP L N+I   +   +  P  + + G+ G GK+ + + ++    L    F     W+ VG  E  D+  ++ SL  +L+       +  P   V+  K +L          ++   + +   +   ++     ++++ ++  + DS + +   + + +G + E+   ++  Y N      P+    I+S+   +PL +S+I  L+    D    Y+R L +K F             LD+ +   ++VL+ E +  Y  L++
Sbjct:    6 RSRLLRSKATLEQDIKASYLMDHMISD----GVLTNDEEAKVLSKATRKEQAVALLETLLRKDNRAYISFYNALIRESYGDLASLLHS-DLPLLSPEGEKSFADGVSPSVQAILSVGGVPQRPVVFVSRPPLLNLIREMLYRLRDTPGWVTVFGMAGSGKSVMAAEVVRDRSLIKECFPDGVHWLSVGQCERADLLVRMQSLCFRLEQCQSSDTSQRPPSTVEEAKERLRFLMLRRFPRSLLILDDVWDSSSLRSFDIQCRVLLTTRNRALTDSVSGVRYEVPVENGLDEEKALEILALYVNGKMHKLPEQARSIVSECKGSPLVVSLIGALLREFPDRWSYYLRQLQQKQFKRIRKSSSYDYEALDQAMDASLQVLEAEHQELYRDLSV 390
[Close]
BLAST of apaf1 vs. Ensembl Zebrafish
Match: apaf1 (apoptotic peptidase activating factor 1 [Source:NCBI gene;Acc:58131])

HSP 1 Score: 51.2174 bits (121), Expect = 6.496e-6
Identity = 86/389 (22.11%), Postives = 166/389 (42.67%), Query Frame = 3 
Query:   93 TEYLRALAYNEDDILEDVIPTDIIPDLRSCKLFTLEDEQIVLHEITDKAKNRKLLDIIKSRPDELYEKFCE-ILRITNEDVAENLESHDYTRTRRVSNTDFGD--------ILIKGGVPDRNVDYVPRPNLENIILNAIISNKKMP--ILIHGIIGCGKTSIVSNLLHSDQLFPYRFLTCC-WMDVGNIEEKDIXXXXXXXXXXXDPSPQLPLNIIPEILVDRIKAKLYDGTTXXXXXXXXXXXXXXXXXXXXTY-----IVVSRQSNLVPDSTAKL---INIPDGFEIEECRSLMKHY-NISEDLFPK----IISKSMKNPLSLSMICKLVHSNGD----YIRMLNEK---------SFNSNHLDKIVQGYIKVLDDELKSKYEMLAI 1145
            +  LR+ A  E DI    +   +I D     + T ++E  VL + T K +   LL+ +  + +  Y  F   ++R +  D+A  L S D           F D        IL  GGVP R V +V RP L N+I   +   +  P  + + G+ G GK+ + + ++    L    F     W+ VG  E  D+  ++ SL  +L+       +  P   V+  K +L          ++   + +   +   ++     ++++ ++  + DS + +   + + +G + E+   ++  Y N      P+    I+S+   +PL +S+I  L+    D    Y+R L +K         S++   LD+ +   ++VL+ E +  Y  L++
Sbjct:    7 SRLLRSKATLEQDIKASYLMDHMISD----GVLTNDEEAKVLSKATRKEQAVALLETLLRKDNRAYISFYNALIRESYGDLASLLHS-DLPLLSPEGEKSFADGVSPSVQAILSVGGVPQRPVVFVSRPPLLNLIREMLYRLRDTPGWVTVFGMAGSGKSVMAAEVVRDRSLIKECFPDGVHWLSVGQCERADLLVRMQSLCFRLEQCQSSDTSQRPPSTVEEAKERLRFLMLRRFPRSLLILDDVWDSSSLRSFDIQCRVLLTTRNRALTDSVSGVRYEVPVENGLDEEKALEILALYVNGKMHKLPEQARSIVSECKGSPLVVSLIGALLREFPDRWSYYLRQLQQKQFKRIRKSSSYDYEALDQAMDASLQVLEAEHQELYRDLSV 390
[Close]
BLAST of apaf1 vs. Ensembl Mouse
Match: Apaf1 (apoptotic peptidase activating factor 1 [Source:MGI Symbol;Acc:MGI:1306796])

HSP 1 Score: 77.0258 bits (188), Expect = 8.626e-14
Identity = 129/587 (21.98%), Postives = 255/587 (43.44%), Query Frame = 3 
Query:  375 VSNTDFGDILIKGGVPDRNVDYVPRPNLENIILNAIISNKKMP--ILIHGIIGCGKTSIVSNLLHSDQLFPYRFLTCC-WMDVGNIEEKDIXXXXXXXXXXXDP----SPQLPLNIIPEILVDRIKA-KLYDGTTXXXXXXXXXXXXXXXXXXXXTYIVVSRQSNLVPDST---AKLINIPDGFEIEECRSLMKHY-NISEDLFP----KIISKSMKNPLSLSMICKLVH-------------SNGDYIRMLNEKSFNSNHLDKIVQGYIKVLDDELKSKYEMLAIXXXXXXXXXXXXXYYWNVSYVKALDMVNKLCDFNLLHKTWNS-TFNINLYGVYDIYLKYL-QQNVTNLQKFKQIFIDNYEAKYKKWLDVKEPDPFFLIFYGKTLFYNKND----EKLIELYTDFSFIAAKIVICGIIYLQNEYEKYKPSDFNSDW---DDFEAFFIKYSHKFMKIPSACKIPTKIGKVFINLIQLALYEPKTSATYKFA-MSCKNKCNWKDFW-EWTNP---RNSIKVWEINHGDNI--TSFDVMKNLIIMSSDSNSMRLLEFSTGKCLLNFKL-RNHILLVKFISDHEFI 1997
            VS++    +L +GGVP R V +V R  L + I   +      P  + I+G+ GCGK+ + +  +    L    F     W+ +G  ++  +  KL +L  +LD     S +LPLNI  E   DR++   L      L++ +   +  +     +   I+++ +   V DS      ++ +  G   E+   ++  + N+ ++  P     II +   +PL +S+I  L+               N  + R+    S++   LD+ +   +++L +++K  Y  L+IL+ D  +  ++L   W++   +  D++ +  + +LL    N  +F    Y ++D+ + +L ++N + LQ   +  +  ++  Y+       PD    +++   L Y+       ++L  L     +I AK  + G  +L +E+  Y+      D    ++F+ F     H   + P            F N++QL L EP+TS  Y+ A +  K + +    + EW N    +N  ++    H D +    F      I       ++++ +  TG+ LL+ K   + +L   F SD  +I
Sbjct:   94 VSSSSVRTVLCEGGVPQRPVIFVTRKKLVHAIQQKLWKLNGEPGWVTIYGMAGCGKSVLAAEAVRDHSLLEGCFSGGVHWVSIGKQDKSGLLMKLQNLCMRLDQEESFSQRLPLNI--EEAKDRLRVLMLRKHPRSLLILDDVWDPWVLKAFDNQCQILLTTRDKSVTDSVMGPKHVVPVESGLGREKGLEILSLFVNMKKEDLPAEAHSIIKECKGSPLVVSLIGALLRDFPNRWAYYLRQLQNKQFKRIRKSSSYDYEALDEAMSISVEMLREDIKDYYTDLSILQKDVKVPTKVLCVLWDLETEEVEDILQEFVNKSLLFCNRNGKSF---CYYLHDLQVDFLTEKNRSQLQDLHRKMVTQFQRYYQP--HTLSPDQEDCMYWYNFLAYHMASANMHKELCALMFSLDWIKAKTELVGPAHLIHEFVAYRHILDEKDCAVCENFQEFLSLNGHLLGRQP------------FPNIVQLGLCEPETSEVYRQAKLQAKQEGDTGRLYLEWINKKTIKNLSRLVVRPHTDAVYHACFSQDGQRIASCGADKTLQVFKAETGEKLLDIKAHEDEVLCCAFSSDDSYI 661
[Close]
BLAST of apaf1 vs. Ensembl Mouse
Match: Apaf1 (apoptotic peptidase activating factor 1 [Source:MGI Symbol;Acc:MGI:1306796])

HSP 1 Score: 74.3294 bits (181), Expect = 5.499e-13
Identity = 127/579 (21.93%), Postives = 252/579 (43.52%), Query Frame = 3 
Query:  399 ILIKGGVPDRNVDYVPRPNLENIILNAIISNKKMP--ILIHGIIGCGKTSIVSNLLHSDQLFPYRFLTCC-WMDVGNIEEKDIXXXXXXXXXXXDP----SPQLPLNIIPEILVDRIKA-KLYDGTTXXXXXXXXXXXXXXXXXXXXTYIVVSRQSNLVPDST---AKLINIPDGFEIEECRSLMKHY-NISEDLFP----KIISKSMKNPLSLSMICKLVH-------------SNGDYIRMLNEKSFNSNHLDKIVQGYIKVLDDELKSKYEMLAIXXXXXXXXXXXXXYYWNVSYVKALDMVNKLCDFNLLHKTWNS-TFNINLYGVYDIYLKYL-QQNVTNLQKFKQIFIDNYEAKYKKWLDVKEPDPFFLIFYGKTLFYNKND----EKLIELYTDFSFIAAKIVICGIIYLQNEYEKYKPSDFNSDW---DDFEAFFIKYSHKFMKIPSACKIPTKIGKVFINLIQLALYEPKTSATYKFA-MSCKNKCN-WKDFWEWTNP---RNSIKVWEINHGDNI--TSFDVMKNLIIMSSDSNSMRLLEFSTGKCLLNFKL-RNHILLVKFISDHEFI 1997
            +L +GGVP R V +V R  L + I   +      P  + I+G+ GCGK+ + +  +    L    F     W+ +G  ++  +  KL +L  +LD     S +LPLNI  E   DR++   L      L++ +   +  +     +   I+++ +   V DS      ++ +  G   E+   ++  + N+ ++  P     II +   +PL +S+I  L+               N  + R+    S++   LD+ +   +++L +++K  Y  L+IL+ D  +  ++L   W++   +  D++ +  + +LL    N  +F    Y ++D+ + +L ++N + LQ   +  +  ++  Y+       PD    +++   L Y+       ++L  L     +I AK  + G  +L +E+  Y+      D    ++F+ F     H   + P            F N++QL L EP+TS  Y+ A +  K + +  + + EW N    +N  ++    H D +    F      I       ++++ +  TG+ LL+ K   + +L   F SD  +I
Sbjct:  113 VLCEGGVPQRPVIFVTRKKLVHAIQQKLWKLNGEPGWVTIYGMAGCGKSVLAAEAVRDHSLLEGCFSGGVHWVSIGKQDKSGLLMKLQNLCMRLDQEESFSQRLPLNI--EEAKDRLRVLMLRKHPRSLLILDDVWDPWVLKAFDNQCQILLTTRDKSVTDSVMGPKHVVPVESGLGREKGLEILSLFVNMKKEDLPAEAHSIIKECKGSPLVVSLIGALLRDFPNRWAYYLRQLQNKQFKRIRKSSSYDYEALDEAMSISVEMLREDIKDYYTDLSILQKDVKVPTKVLCVLWDLETEEVEDILQEFVNKSLLFCNRNGKSF---CYYLHDLQVDFLTEKNRSQLQDLHRKMVTQFQRYYQP--HTLSPDQEDCMYWYNFLAYHMASANMHKELCALMFSLDWIKAKTELVGPAHLIHEFVAYRHILDEKDCAVCENFQEFLSLNGHLLGRQP------------FPNIVQLGLCEPETSEVYRQAKLQAKQEGDTGRLYLEWINKKTIKNLSRLVVRPHTDAVYHACFSQDGQRIASCGADKTLQVFKAETGEKLLDIKAHEDEVLCCAFSSDDSYI 672
[Close]
BLAST of apaf1 vs. Ensembl Mouse
Match: Apaf1 (apoptotic peptidase activating factor 1 [Source:MGI Symbol;Acc:MGI:1306796])

HSP 1 Score: 74.3294 bits (181), Expect = 5.499e-13
Identity = 127/579 (21.93%), Postives = 252/579 (43.52%), Query Frame = 3 
Query:  399 ILIKGGVPDRNVDYVPRPNLENIILNAIISNKKMP--ILIHGIIGCGKTSIVSNLLHSDQLFPYRFLTCC-WMDVGNIEEKDIXXXXXXXXXXXDP----SPQLPLNIIPEILVDRIKA-KLYDGTTXXXXXXXXXXXXXXXXXXXXTYIVVSRQSNLVPDST---AKLINIPDGFEIEECRSLMKHY-NISEDLFP----KIISKSMKNPLSLSMICKLVH-------------SNGDYIRMLNEKSFNSNHLDKIVQGYIKVLDDELKSKYEMLAIXXXXXXXXXXXXXYYWNVSYVKALDMVNKLCDFNLLHKTWNS-TFNINLYGVYDIYLKYL-QQNVTNLQKFKQIFIDNYEAKYKKWLDVKEPDPFFLIFYGKTLFYNKND----EKLIELYTDFSFIAAKIVICGIIYLQNEYEKYKPSDFNSDW---DDFEAFFIKYSHKFMKIPSACKIPTKIGKVFINLIQLALYEPKTSATYKFA-MSCKNKCN-WKDFWEWTNP---RNSIKVWEINHGDNI--TSFDVMKNLIIMSSDSNSMRLLEFSTGKCLLNFKL-RNHILLVKFISDHEFI 1997
            +L +GGVP R V +V R  L + I   +      P  + I+G+ GCGK+ + +  +    L    F     W+ +G  ++  +  KL +L  +LD     S +LPLNI  E   DR++   L      L++ +   +  +     +   I+++ +   V DS      ++ +  G   E+   ++  + N+ ++  P     II +   +PL +S+I  L+               N  + R+    S++   LD+ +   +++L +++K  Y  L+IL+ D  +  ++L   W++   +  D++ +  + +LL    N  +F    Y ++D+ + +L ++N + LQ   +  +  ++  Y+       PD    +++   L Y+       ++L  L     +I AK  + G  +L +E+  Y+      D    ++F+ F     H   + P            F N++QL L EP+TS  Y+ A +  K + +  + + EW N    +N  ++    H D +    F      I       ++++ +  TG+ LL+ K   + +L   F SD  +I
Sbjct:  113 VLCEGGVPQRPVIFVTRKKLVHAIQQKLWKLNGEPGWVTIYGMAGCGKSVLAAEAVRDHSLLEGCFSGGVHWVSIGKQDKSGLLMKLQNLCMRLDQEESFSQRLPLNI--EEAKDRLRVLMLRKHPRSLLILDDVWDPWVLKAFDNQCQILLTTRDKSVTDSVMGPKHVVPVESGLGREKGLEILSLFVNMKKEDLPAEAHSIIKECKGSPLVVSLIGALLRDFPNRWAYYLRQLQNKQFKRIRKSSSYDYEALDEAMSISVEMLREDIKDYYTDLSILQKDVKVPTKVLCVLWDLETEEVEDILQEFVNKSLLFCNRNGKSF---CYYLHDLQVDFLTEKNRSQLQDLHRKMVTQFQRYYQP--HTLSPDQEDCMYWYNFLAYHMASANMHKELCALMFSLDWIKAKTELVGPAHLIHEFVAYRHILDEKDCAVCENFQEFLSLNGHLLGRQP------------FPNIVQLGLCEPETSEVYRQAKLQAKQEGDTGRLYLEWINKKTIKNLSRLVVRPHTDAVYHACFSQDGQRIASCGADKTLQVFKAETGEKLLDIKAHEDEVLCCAFSSDDSYI 672
[Close]
BLAST of apaf1 vs. UniProt/SwissProt
Match: sp|O14727|APAF_HUMAN (Apoptotic protease-activating factor 1 OS=Homo sapiens OX=9606 GN=APAF1 PE=1 SV=2)

HSP 1 Score: 82.8037 bits (203), Expect = 8.011e-15
Identity = 160/691 (23.15%), Postives = 289/691 (41.82%), Query Frame = 3 
Query:  129 DILEDVIPTDIIPD-LRSCKLFTLEDEQIVLHEITDKAKNRKLLDIIKSRPDELYEKFC-EILRITNEDVAENLESHD-------------------YTRTRRVSNTDFGDILIKGGVPDRNVDYVPRPNLENIILNAIISNKKMP--ILIHGIIGCGKTSIVSNLLHSDQLFPYRFLTCC-WMDVGNIEEKDIXXXXXXXXXXXDP----SPQLPLNIIPEILVDRIK-AKLYDGTTXXXXXXXXXXXXXXXXXXXXTYIVVSRQSNLVPDST---------AKLINIPDGFEIEECRSLMKHYNISEDLFPKIISKSMKNPLSLSMICKLVH-------------SNGDYIRMLNEKSFNSNHLDKIVQGYIKVLDDELKSKYEMLAIXXXXXXXXXXXXXYYWNVSYVKALDMVNKLCDFNLLHKTWNS-TFNINLYGVYDIYLKYL-QQNVTNLQKFKQIFIDNYEAKYKKWLDVKEPDPFFLIFYGKTLFYN----KNDEKLIELYTDFSFIAAKIVICGIIYLQNEYEKYKPSDFNSDW---DDFEAFFIKYSHKFMKIPSACKIPTKIGKVFINLIQLALYEPKTSATYKFA-MSCKNKC-NWKDFWEWTNPRNSIKVWEI---NHGDNI--TSFDVMKNLIIMSSDSNSMRLLEFSTGKCLLNFKLR-NHILLVKFISDHEFI 1997
            + LE  I T  I D + S    T+ +E+ V +E T + +   L+ +I  + ++ Y  F   +L    +D+A  L  HD                   Y RT          +L +GGVP R V +V R  L N I   +   K  P  + IHG+ GCGK+ + +  +    L    F     W+ VG  ++  +  KL +L  +LD     S +LPLNI  E   DR++   L      L++ +   ++ +         I+++ +   V DS             +    G EI      MK  ++ E     II +   +PL +S+I  L+               N  + R+    S++   LD+ +   +++L +++K  Y  L+IL+ D  +  ++L   W++   +  D++ +  + +LL    N  +F    Y ++D+ + +L ++N + LQ   +  I  ++  ++       PD    +++   L Y+    K  ++L  L     +I AK  + G  +L +E+ +Y+      D    ++F+ F     H   + P            F N++QL L EP+TS  Y+ A +  K +  N   + EW N +N   +  +    H D +    F      I       ++++ +  TG+ LL  K   + +L   F +D  FI
Sbjct:   14 EALEKDIKTSYIMDHMISDGFLTISEEEKVRNEPTQQQRAAMLIKMILKKDNDSYVSFYNALLHEGYKDLAALL--HDGIPVVSSSSGKDSVSGITSYVRT----------VLCEGGVPQRPVVFVTRKKLVNAIQQKLSKLKGEPGWVTIHGMAGCGKSVLAAEAVRDHSLLEGCFPGGVHWVSVGKQDKSGLLMKLQNLCTRLDQDESFSQRLPLNI--EEAKDRLRILMLRKHPRSLLILDDVWDSWVLKAFDSQCQILLTTRDKSVTDSVMGPKYVVPVESSLGKEKGLEILSLFVNMKKADLPEQAHS-IIKECKGSPLVVSLIGALLRDFPNRWEYYLKQLQNKQFKRIRKSSSYDYEALDEAMSISVEMLREDIKDYYTDLSILQKDVKVPTKVLCILWDMETEEVEDILQEFVNKSLLFCDRNGKSFR---YYLHDLQVDFLTEKNCSQLQDLHKKIITQFQRYHQP--HTLSPDQEDCMYWYNFLAYHMASAKMHKELCALMFSLDWIKAKTELVGPAHLIHEFVEYRHILDEKDCAVSENFQEFLSLNGHLLGRQP------------FPNIVQLGLCEPETSEVYQQAKLQAKQEVDNGMLYLEWINKKNITNLSRLVVRPHTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSTDDRFI 672
[Close]
BLAST of apaf1 vs. UniProt/SwissProt
Match: sp|O88879|APAF_MOUSE (Apoptotic protease-activating factor 1 OS=Mus musculus OX=10090 GN=Apaf1 PE=1 SV=3)

HSP 1 Score: 74.3294 bits (181), Expect = 3.847e-12
Identity = 127/579 (21.93%), Postives = 252/579 (43.52%), Query Frame = 3 
Query:  399 ILIKGGVPDRNVDYVPRPNLENIILNAIISNKKMP--ILIHGIIGCGKTSIVSNLLHSDQLFPYRFLTCC-WMDVGNIEEKDIXXXXXXXXXXXDP----SPQLPLNIIPEILVDRIKA-KLYDGTTXXXXXXXXXXXXXXXXXXXXTYIVVSRQSNLVPDST---AKLINIPDGFEIEECRSLMKHY-NISEDLFP----KIISKSMKNPLSLSMICKLVH-------------SNGDYIRMLNEKSFNSNHLDKIVQGYIKVLDDELKSKYEMLAIXXXXXXXXXXXXXYYWNVSYVKALDMVNKLCDFNLLHKTWNS-TFNINLYGVYDIYLKYL-QQNVTNLQKFKQIFIDNYEAKYKKWLDVKEPDPFFLIFYGKTLFYNKND----EKLIELYTDFSFIAAKIVICGIIYLQNEYEKYKPSDFNSDW---DDFEAFFIKYSHKFMKIPSACKIPTKIGKVFINLIQLALYEPKTSATYKFA-MSCKNKCN-WKDFWEWTNP---RNSIKVWEINHGDNI--TSFDVMKNLIIMSSDSNSMRLLEFSTGKCLLNFKL-RNHILLVKFISDHEFI 1997
            +L +GGVP R V +V R  L + I   +      P  + I+G+ GCGK+ + +  +    L    F     W+ +G  ++  +  KL +L  +LD     S +LPLNI  E   DR++   L      L++ +   +  +     +   I+++ +   V DS      ++ +  G   E+   ++  + N+ ++  P     II +   +PL +S+I  L+               N  + R+    S++   LD+ +   +++L +++K  Y  L+IL+ D  +  ++L   W++   +  D++ +  + +LL    N  +F    Y ++D+ + +L ++N + LQ   +  +  ++  Y+       PD    +++   L Y+       ++L  L     +I AK  + G  +L +E+  Y+      D    ++F+ F     H   + P            F N++QL L EP+TS  Y+ A +  K + +  + + EW N    +N  ++    H D +    F      I       ++++ +  TG+ LL+ K   + +L   F SD  +I
Sbjct:  113 VLCEGGVPQRPVIFVTRKKLVHAIQQKLWKLNGEPGWVTIYGMAGCGKSVLAAEAVRDHSLLEGCFSGGVHWVSIGKQDKSGLLMKLQNLCMRLDQEESFSQRLPLNI--EEAKDRLRVLMLRKHPRSLLILDDVWDPWVLKAFDNQCQILLTTRDKSVTDSVMGPKHVVPVESGLGREKGLEILSLFVNMKKEDLPAEAHSIIKECKGSPLVVSLIGALLRDFPNRWAYYLRQLQNKQFKRIRKSSSYDYEALDEAMSISVEMLREDIKDYYTDLSILQKDVKVPTKVLCVLWDLETEEVEDILQEFVNKSLLFCNRNGKSF---CYYLHDLQVDFLTEKNRSQLQDLHRKMVTQFQRYYQP--HTLSPDQEDCMYWYNFLAYHMASANMHKELCALMFSLDWIKAKTELVGPAHLIHEFVAYRHILDEKDCAVCENFQEFLSLNGHLLGRQP------------FPNIVQLGLCEPETSEVYRQAKLQAKQEGDTGRLYLEWINKKTIKNLSRLVVRPHTDAVYHACFSQDGQRIASCGADKTLQVFKAETGEKLLDIKAHEDEVLCCAFSSDDSYI 672
[Close]
BLAST of apaf1 vs. UniProt/SwissProt
Match: sp|Q9EPV5|APAF_RAT (Apoptotic protease-activating factor 1 OS=Rattus norvegicus OX=10116 GN=Apaf1 PE=1 SV=1)

HSP 1 Score: 70.0922 bits (170), Expect = 8.189e-11
Identity = 129/588 (21.94%), Postives = 256/588 (43.54%), Query Frame = 3 
Query:  378 SNTDF-GDILIKGGVPDRNVDYVPRPNLENIILNAIISNKKMP--ILIHGIIGCGKTSIVSNLLHSDQLFPYRFLTCC-WMDVGNIEEKDIXXXXXXXXXXXDP----SPQLPLNIIPEILVDRIKA-KLYDGTTXXXXXXXXXXXXXXXXXXXXTYIVVSRQSNLVPDSTAK---LINIPDGFEIEECRSLMKHY-NISEDLFP----KIISKSMKNPLSLSMICKLVH-------------SNGDYIRMLNEKSFNSNHLDKIVQGYIKVLDDELKSKYEMLAIXXXXXXXXXXXXXYYWNVSYVKALDMVNKLCDFNLLHKTWNS-TFNINLYGVYDIYLKYL-QQNVTNLQKFKQIFIDNYEAKYK-KWLDVKEPDPF----FLIFYGKTLFYNKNDEKLIELYTDFSFIAAKIVICGIIYLQNEYEKYKPSDFNSDW---DDFEAFFIKYSHKFMKIPSACKIPTKIGKVFINLIQLALYEPKTSATYKFA-MSCKNKCN-WKDFWEWTNP---RNSIKVWEINHGDNI--TSFDVMKNLIIMSSDSNSMRLLEFSTGKCLLNFKL-RNHILLVKFISDHEFI 1997
             NT F   +L +GGVP R V +V R  L + I   +      P  + I+G+ GCGK+ + +  +    L    F     W+ +G  ++  +  KL +L  +L      S +LPLNI  E   DR++   L      L++ +   +  +     +   I+++ +   V DS      +I +  G   E+   ++  + N+ ++  P     II +   +PL +S++  L+               N  + R+    S++   LD+ +   +++L +++K  Y  L+IL+ D  +  ++L   W++   +  D++ +  + +LL    N  +F    Y ++D+ + +L ++N + LQ   +  +  ++  ++   L   + D      FL ++  +   +K   +L  L     +I AK  + G  +L +E+ +Y+      D    ++F+ F     H   + P            F N++QL L EP+TS  Y+ A +  K + +  + + EW N    +N  ++    H D +    F      I       ++++ +  TG+ LL+ K   + +L   F SD  +I
Sbjct:  105 GNTSFVRTVLCEGGVPQRPVIFVTRKKLVSAIQQKLWKLNGEPGWVTIYGMAGCGKSVLAAEAVRDHALLEGCFSGGVHWVSIGKQDKSGLLMKLQNLCTRLGQEESFSQRLPLNI--EEAKDRLRVLMLRKHPRSLLILDDVWDPWVLKAFDNQCQILLTTRDKSVTDSVMGPKYVIPVESGLGKEKGLEILSLFVNMKKEDLPVEAHSIIKECKGSPLVVSLVGALLRDFPNRWAYYLRQLQNKQFKRIRKSSSYDYEALDEAMSISVEMLREDIKDYYTDLSILQKDVKVPTKVLCVLWDLETEEVEDILQEFVNKSLLFCNRNGKSF---CYYLHDLQVDFLTEKNRSQLQDLHRKMVTQFQRYHQPHTLSPGQEDCMYWYNFLAYHMASAGMHK---ELCALMFSLDWIKAKTELVGPAHLIHEFVEYRHILDEKDCAVCENFQEFLSLNGHLLGRQP------------FPNIVQLGLCEPETSEVYQQAKLQAKQEVDTGRLYLEWINKKTIKNLSRLVVRPHTDAVYHACFSQDGQRIASCGADKTLQVFKAETGEKLLDIKAHEDEVLCCAFSSDDSYI 672
[Close]
BLAST of apaf1 vs. TrEMBL
Match: H2DL11 (Apaf1 OS=Schmidtea mediterranea OX=79327 PE=2 SV=1)

HSP 1 Score: 1211.82 bits (3134), Expect = 0.000e+0
Identity = 643/647 (99.38%), Postives = 645/647 (99.69%), Query Frame = 3 
Query:   84 MNNTEYLRALAYNEDDILEDVIPTDIIPDLRSCKLFTLEDEQIVLHEITDKAKNRKLLDIIKSRPDELYEKFCEILRITNEDVAENLESHDYTRTRRVSNTDFGDILIKGGVPDRNVDYVPRPNLENIILNAIISNKKMPILIHGIIGCGKTSIVSNLLHSDQLFPYRFLTCCWMDVGNIEEKDIXXXXXXXXXXXDPSPQLPLNIIPEILVDRIKAKLYDGTTXXXXXXXXXXXXXXXXXXXXTYIVVSRQSNLVPDSTAKLINIPDGFEIEECRSLMKHYNISEDLFPKIISKSMKNPLSLSMICKLVHSNGDYIRMLNEKSFNSNHLDKIVQGYIKVLDDELKSKYEMLAIXXXXXXXXXXXXXYYWNVSYVKALDMVNKLCDFNLLHKTWNSTFNINLYGVYDIYLKYLQQNVTNLQKFKQIFIDNYEAKYKKWLDVKEPDPFFLIFYGKTLFYNKNDEKLIELYTDFSFIAAKIVICGIIYLQNEYEKYKPSDFNSDWDDFEAFFIKYSHKFMKIPSACKIPTKIGKVFINLIQLALYEPKTSATYKFAMSCKNKCNWKDFWEWTNPRNSIKVWEINHGDNITSFDVMKNLIIMSSDSNSMRLLEFSTGKCLLNFKLRNHILLVKFISDHEFIIIFENGEFW 2024
            MNNTEYLRALAYNEDDILEDVIPTDI+PDLRSCKLFTLEDEQIVLHEITDKAKNRKLLDIIKSRPDELYEKFCEILRITNEDVAENLESHDYTRTRRVSNTDFGDILIKGGVPDRNVDYVPRPNLEN ILNAIISNKKMPILIHGIIGCGKTSIVSNLLHSDQLFPYRFLTCCWMDVGNIEEKDINNKLLSLLNKLDPSPQLPLNIIPEILVDRIKAKLYDGTTLLILDNIWNNNILHHFNFHNTYIVVSRQSNLVPDSTAKLINIPDGFEIEECRSLMKHY+ISEDLFPKIIS SMKNPLSLSMICKLVHSNGDYIRMLNEKSFNSNHLDKIVQGYIKVLDDELKSKYEMLAILEDDETLSLELLSYYWNVSYVKALDMVNKLCDFNLLHKTWNSTFNINLYGVYDIYLKYLQQNVTNLQKFKQIFIDNYEAKYKKWLDVKEPDPFFLIFYGKTLFYNKNDEKLIELYTDFSFIAAKIVICGIIYLQNEYEKYKPSDFNSDWDDFEAFFIKYSHKFMKIPSACKIPTKIGKVFINLIQLALYEPKTSATYKFAMSCKNKCNWKDFWEWTNPRNSIKVWEINHGDNITSFDVMKNLIIMSSDSNSMRLLEFSTGKCLLNFKLRNHILLVKFISDHEFIIIFENGEFW
Sbjct:    1 MNNTEYLRALAYNEDDILEDVIPTDIVPDLRSCKLFTLEDEQIVLHEITDKAKNRKLLDIIKSRPDELYEKFCEILRITNEDVAENLESHDYTRTRRVSNTDFGDILIKGGVPDRNVDYVPRPNLENTILNAIISNKKMPILIHGIIGCGKTSIVSNLLHSDQLFPYRFLTCCWMDVGNIEEKDINNKLLSLLNKLDPSPQLPLNIIPEILVDRIKAKLYDGTTLLILDNIWNNNILHHFNFHNTYIVVSRQSNLVPDSTAKLINIPDGFEIEECRSLMKHYDISEDLFPKIISTSMKNPLSLSMICKLVHSNGDYIRMLNEKSFNSNHLDKIVQGYIKVLDDELKSKYEMLAILEDDETLSLELLSYYWNVSYVKALDMVNKLCDFNLLHKTWNSTFNINLYGVYDIYLKYLQQNVTNLQKFKQIFIDNYEAKYKKWLDVKEPDPFFLIFYGKTLFYNKNDEKLIELYTDFSFIAAKIVICGIIYLQNEYEKYKPSDFNSDWDDFEAFFIKYSHKFMKIPSACKIPTKIGKVFINLIQLALYEPKTSATYKFAMSCKNKCNWKDFWEWTNPRNSIKVWEINHGDNITSFDVMKNLIIMSSDSNSMRLLEFSTGKCLLNFKLRNHILLVKFISDHEFIIIFENGEFW 647
[Close]
BLAST of apaf1 vs. TrEMBL
Match: C3YZV6 (Uncharacterized protein OS=Branchiostoma floridae OX=7739 GN=BRAFLDRAFT_276588 PE=4 SV=1)

HSP 1 Score: 124.405 bits (311), Expect = 3.804e-25
Identity = 147/679 (21.65%), Postives = 296/679 (43.59%), Query Frame = 3 
Query:  108 ALAYNEDDILEDVIPTDIIPDLRSCKLFTLEDEQIVLHEITDKAKNRKLLDIIKSRPD--------ELYEKFCEILRITNEDV--AENLESHDYTRTRRVSNTDFGDILIKGGVPDRNVDYVPRPNLENIILNAIISNKKMP--ILIHGIIGCGKTSIVSNLLHSDQL----FPYRFLTCCWMDVGNIEEKDIXXXXXXXXXXXDPSPQLPLNIIPEILVDRIKAKL-YDGTTXXXXXXXXXXXXXXXXXXXXTYIVVSRQSNLVPDSTA---KLINIPDGFEIEECRSLMKHYNISE--DLFP---KIISKSMKNPLSLSMICKLVHSNGD----YIRMLNEKSFNS---------NHLDKIVQGYIKVLDDELKSKYEMLAIXXXXXXXXXXXXXYYWNVSYVKALDMVNKLCDFNLLHKTWNSTFNINLYGVYDIYLKYLQQNVTNLQKFKQIFIDNYEAKYKKWLDVKEPDPFFLIFYGKTLFYNKNDEKLIELYTDFSFIAAKIVICGIIYLQNEYEKYKP---SDFNSDWDDFEAFFIKYSHKFMKIPSACKIPTKIGKVFINLIQLALYEPKTSATYKFAMSCKNKCNWKDFWEWTNPRNSIK------VWEINHGDNITSFDVMKNLIIMSSDSNSMRLLEFSTGKCLLNFKL-RNHILLVKFISDHEFII 2000
            +L  N   I++D+    +I  L S K+ TL+DE+ +  E T K +  KLLDI+ SR +         L +++  +  +  +D+  ++ LE       R++S  D   +L++GGVP R   ++ RP     I NA+   K  P  +++HG+ G GK+ + S ++   +L    FP       W+ +G +++  +  K+ +L + LD   Q P     E   DR++    +     L++ +                 +V+ + + V D+      ++ I +GF  E+   ++  +  ++  DL P   +I ++   +PL++ MI  L+  + +    Y+++L  K  +            L + +   +  LD E++  Y+  A+ ++D  +  ++LS  W        D +++LC  +L  ++W+      +Y V+D+ L YL++   ++Q      +  YE   K      + D +        L  +     L  + +   ++ +K+ I G  +L  +Y K+      +      DFE+F     H+F + P            F ++IQL L +   S  Y+ A+S   + N   ++ W+  ++++K      V   + G +   F    N +    +  S+++ +  TG+  L  +  R+ +    F  D   I+
Sbjct:    8 SLLVNRVSIIKDLKVQHVINPLLSAKVLTLDDEEEIFAETTSKRRAAKLLDILPSRGNLAFVSLYKSLQDQYSHLAELLAKDLPTSDRLEKIQNGGKRKMSTIDVETVLVEGGVPPRPRVFIKRPVQSQQIRNALQQLKDEPGWVVVHGMGGSGKSVLASEVVREQELLEECFPGGVF---WVSLGQVDKPMLLMKMQNLCSLLDKEHQAPPRNAEEA-KDRLRLLFTHQHPRALLILDDVWTARDAKMFDVRCRTMVTTRDSSVTDAVRGNISMVPIREGFSKEQSDEVLATWTETKVSDLPPEAGQIYTECGGHPLAICMIGALLKDHPNRWQYYLKLLQNKKMSKFKKTLPYEYQSLAEAIAISVDHLDTEIRDLYQQFAVFDNDTLVPTQVLSILWAEEIEFVEDTMDELCKKSLAFQSWDEKQKTFVYTVHDLQLDYLKEQCDDMQSLHATLVSRYEKVCKGEFHTLQDDGYIHWHMEDHLAASGRVNDLCSILSSLDWVGSKVKITGPSFLVEQYVKHGKILCQNRGQQLRDFESFLRTNLHRFFEDP------------FPDIIQLGLNQYSKSEVYQQALSRATQ-NDSCYFVWSG-KDTVKDPTQLTVKVHSGGVHFAKFSPDGNRVASCGEDCSIKVWDAHTGQVQLTLEGHRDVVYCCGFSPDGATIV 668
[Close]
BLAST of apaf1 vs. TrEMBL
Match: A0A2B4SA85 (Apoptotic protease-activating factor 1 OS=Stylophora pistillata OX=50429 GN=apaf1 PE=4 SV=1)

HSP 1 Score: 118.242 bits (295), Expect = 3.871e-23
Identity = 168/733 (22.92%), Postives = 303/733 (41.34%), Query Frame = 3 
Query:  129 DILEDVIPTDIIPDLRSCKLFTLEDEQIVLHEITDKAKNRKLLDIIKSRPDELYEKFCEILRITNEDVAENLESHDYTRTRRVSNTD-----FGDILIKGGVPDRNVDYVPRPNLENIILNAIISNKKMP--ILIHGIIGCGKTSIVSNLLHS----DQLFPYRFLTCCWMDVGNIEEKDIXXXXXXXXXXXDP--SPQLPLN--------------------IIPEILVDRIKAKLYDGTTXXXXXXXXXXXXXXXXXXXXTYIVVSRQS---NLVPDSTAKLINIPDGF-EIEECRSLMKHYNISEDLFP----KIISKSMKNPLSLSMICKLVHSNGD----YIRMLNEKS---------FNSNHLDKIVQGYIKVLDDELKSKYEMLAIXXXXXXXXXXXXXYYWNVSYVKALDMVNKLCDFNLLHKTWNSTFNINL-YGVYDIYLKYLQQNVTNLQKFKQIFIDNYEAKYKKWLDVKEPDPFFLIFYGKTLFYNKNDEKLIELYTDFSFIAAKIVICGIIYLQNEYEKYKPSDFNSDW---DDFEAFFIKYSHKFMKIPSACKIPTKIGKVFINLIQLALYEPKTSATYKFAM--SCKNKCNWKDFWEWTNPRN------------------------------------SIKVWEINHGDNITS------------FDVMKNLIIMSSDSNSMRLLEFSTGKCLLNFKLRNH-ILLVKFISDHEFII 2000
            +I+ED++  D++  L+S  +F + D +++  E T + + RKLLD+++++ D  +  F E L      + E L+  D T  R+ S+         ++L++GGVP R   +  R    + I  A+ S K+    +++HG+ GCGKT + S  L      D+ FP       W+ +G +++  +   + +L  +LD   S Q P N                    +I + L D    K +D                         +V +R +   ++V  S AK ++I +GF E E  + L +     +   P    +I   +  +PL++SMI  L+  +      Y+  L +K+         +    L + ++  I  L DEL+  YE  A+  +D  +  ++LS  W+  +    D +  L + +L  +T NS   I   Y V+++ L +LQ+  TNL+   +  +D Y   YK        D +      + +      E+  +L TD S++AAK+ + G   L N+Y   K  + + +     DF  F    +H+F++ P              +LIQ+ L E + S  YK A   + + + +   + +W+N R                                     ++KVWE   G  + S            F      I+  S  + +++ + S+GK LL F   N  +    F  D + I+
Sbjct: 1096 EIVEDLLVDDVLNFLQSKMVFDVHDTELIRAETTSRGQARKLLDLLETKSDAAFYHFREALEEPYPHLVELLK-EDATAPRKESSAKELLERVKNVLLEGGVPQRPAVFAHRGKDIHKIRTALKSLKEKDGWVILHGMAGCGKTVLASEALRGAAVLDECFPGGVH---WIRIGPVDQPKLLMHMQNLCARLDSDHSRQPPRNTEEAKDRLRMLFAHQHPRSLLILDDLWDSCDVKFFD--------------------VRCRIMVTTRDAAITDMVGGSKAK-VHISEGFTEGESLQILAEWTKQPKTNLPAEAKEIFQLTNGSPLAISMIGALLRDHPKRWKYYVSQLKKKNVSKLKTQFEYQYPTLTEAIRMSINNLPDELRHIYESFAVFCEDCKVPAQVLSILWDEEFEVVEDWMEALVNKSLARRTVNSEDAIGTWYTVHNLQLTFLQEQATNLEALHKKLVDRYRKVYKGNFSEMTNDGYIHRNLLRHMLRAGLVEEAQKLITDPSWLAAKLDVTGPADLLNDYLSIKGREDSKELKVIGDFNHFVSVNAHQFVEKP------------LPDLIQMGLSESRDSEVYKQAHDKAIQAQGDGNFYLDWSNQREESQDTLLITVKIHQGAVYCCGFSQDASRVVSCGADKTVKVWEGQSGKELLSMTSHTDAVYCCTFSTDDARIVSCSADHKVKIWDSSSGKELLTFSGHNQEVFKCMFSPDDQKIV 1791
[Close]
BLAST of apaf1 vs. TrEMBL
Match: A0A3M6V2D9 (Uncharacterized protein OS=Pocillopora damicornis OX=46731 GN=pdam_00004549 PE=4 SV=1)

HSP 1 Score: 108.612 bits (270), Expect = 2.673e-20
Identity = 147/595 (24.71%), Postives = 276/595 (46.39%), Query Frame = 3 
Query:   84 MNNTEYLRALAYNEDDILEDVIPTDIIPDLRSCKLFTLEDEQIVLHEITDKAKNRKLLDIIKSRPDELYEKFCEILRITNEDVAENLESHDYTRTRRVSNTD-----FGDILIKGGVPDRNVDYVPRPNLENIILNAIISNKKMP--ILIHGIIGCGKTSIVSNLLHS----DQLFPYRFLTCCWMDVGNIEEKDIXXXXXXXXXXXDP--SPQLPLNIIPEILVDRIKAKLYDG--TTXXXXXXXXXXXXXXXXXXXXTYIVVSRQS---NLVPDSTAKLINIPDGFEIEECRSLMKHY--NISEDLFP----KIISKSMKNPLSLSMICKLVHSNGD----YIRMLNEKS---------FNSNHLDKIVQGYIKVLDDELKSKYEMLAIXXXXXXXXXXXXXYYWNVSYVKALDMVNKLCDFNLLHKTWNSTFNINL-YGVYDIYLKYLQQNVTNLQKFKQIFIDNYEAKYKKWLDVKEPDPFFLIFYGKTLFYNKNDEKLIELYTDFSFIAAKIVICGIIYLQNEYEKYKPSDFNSDW---DDFEAFFIKYSHKFMKIPSACKIPTKIGKVFINLIQLALYEPKTSATYKFA 1745
            M   ++   L  N  +I+ED++  D      S  +F + D +++  E+T + +  KLLD+++++ D  +  F + L      + E L+  +    R+VS          ++L++GGVP R   +  R    + I  A+ S K+    +++HG+ GCGKT + S  L S    D+ FP       W+ +G +++  +   + +L  +LD   + Q P N   E   DR++         +LLILD++W++  +  F+     IV +R +   ++V  S AK ++I +GF  +E   ++  +   + +   P    +I   +  +PL++SMI  L+  +      Y++ L +K+         +    L + ++  I  L DEL+  YE  A+  +D  +  ++L   WN  +    D +  L + +L  +T +S   I   Y V+++ L +L +  TNL+   +  +D Y   YK      + D +      + +      E+  +L TD  ++AAK+ + G   L N+Y   K  + + +    +DF  F    +H+F++ P    +P        +LIQ+ L E + S  YK A
Sbjct:  113 MMTQDHANLLIANRVEIVEDLLVDD------SKMVFDVHDTELIRAEVTSRRQAGKLLDLLETKNDAAFYHFRKALEEPYPHLVEYLQ-ENAAAPRKVSKAKELSERVENVLLEGGVPQRPAIFAHRGRDIHKIHAALKSLKERDGWVILHGMAGCGKTVLASEALRSAVVLDECFPGGVH---WIRIGPVDQPKLLMHMQNLCARLDSDHNRQPPRNT--EEAKDRLRVLFAHQHPRSLLILDDLWDSCDVKFFDVRCRIIVTTRDAAITDMVGGSKAK-VHISEGFTEDESLQILAEWTKQLPKKNLPAEAKEIFKLTNGSPLAISMIGALLRDHPTRWEYYVKQLKKKNVSKLKPQFEYQYPTLTEAIRMSINNLPDELRDIYESFAVFHEDCKVPAQVLIILWNEEFEVVEDWMEDLVNKSLARRTVDSEDAIGTWYTVHNLQLTFLHEQATNLEALHKKLVDRYRKVYKGNFSEMKNDGYIHRNLLRHMLRAGLIEEAQQLITDLKWLAAKLDVTGPADLLNDYLAVKGHEDSKELKVINDFHHFVSVNAHRFVEKP----LP--------DLIQMGLSESRDSEVYKQA 682
[Close]
BLAST of apaf1 vs. TrEMBL
Match: H2MKX5 (Apoptotic protease-activating factor 1 OS=Oryzias latipes OX=8090 GN=apaf1 PE=4 SV=2)

HSP 1 Score: 108.227 bits (269), Expect = 3.336e-20
Identity = 160/695 (23.02%), Postives = 307/695 (44.17%), Query Frame = 3 
Query:   96 EYLRALAYNEDDILEDVI-PTDIIPDLRSCKLFTLEDEQIVLHEITDKAKNRKLLDIIKSRPDELYEKFCEILRITNEDVAENLESHDYTRTRRVSNTD--FGDILIKGGVPDRNVDYVPRPNLENIILNAIISNKKMP--ILIHGIIGCGKTSIVSNLLHSDQLFPYRFLTCC-WMDVGNIEEKDIXXXXXXXXXXXDPSPQLPLNIIPEILVDRIKAKLY------DGTTXXXXXXXXXXXXXXXXXXXXTYIVVSRQSNL--VPDSTAKLINIPDGF------EIEECRSLMKHYNISEDLFPKIISKSMKNPLSLSMICKLVHSNGD----YIRMLNEK---------SFNSNHLDKIVQGYIKVLDDELKSKYEMLAIXXXXXXXXXXXXXYYWNVSYVKALDMVNKLCDFNLLHKTWNSTFNINLYGVYDIYLKY-LQQNVTNLQKFKQIFIDNYEAKYK-KWLDVKEPDPFFLIFYGKTLFYNKND-EKLIELYTDFSFIAAKIVICGIIYLQNEYEKYKP---SDFNSDWDDFEAFFIKYSHKFMKIPSACKIPTKIGKVFINLIQLALYEPKTSATYKFA--MSCKNKCNWKDFWEWTNP--------------RNSIKVWEINHGDNITSFDVMKNLIIMSSDSNSMRLLEFSTGKCLLNFKLRNHILLVKFISDHEFIIIFENG 2015
            E  RA        LE+++ P  ++  + S +  T+E+E ++ ++ T + +   L+D++  + +  +  F   L     D   NL   D   T+  S++      +L +GGVP R   +V RP  EN I   +   +K P  + + G+ G GK+ + S  +   +L    F     W+ +G +++ D+  K+ +L  +L+ +        P   +D  K +L          TLLILD++W++ +L   + H   ++ +R  +L  V + +   + +  G       EI    S ++ Y + E+    I+ K   +PL++SMI  L+  N D    Y+R L +K         S+N   LD+ +   I+ L D+ +  Y +L +L  D  ++ +++S  W    V   D +++  +  +L    +S    N++ ++D+ L + L+QN   L+   +  ++ Y+ +YK + L  ++ +  + I Y      N N  ++L  L     +I+ K  I G  +L N+Y +Y      + N    +F+ F     H   + P            F +++QLAL +P TS  Y+ A  ++ +   + K +++  N               + S+     N G  I S    KNL +  S          ++G+ L  F+LR+ ++   F  D   + +  +G
Sbjct:    5 ERARACLLKSRHKLEEIMKPAYLMDHMISDEAITVEEEDMIANQNTKREQAAALVDLLLKKDNYSFRSFYNALLKEEYDELANLLKEDLPLTQFTSSSQCPVQTVLSEGGVPPRPEAFVHRPKEENEIREKLYKLQKQPGWVTVFGMAGSGKSVLASEAVRHKELIEECFPEGIHWVSIGRLDKPDLLAKIQTLCFRLEQNLDSQQFHRPPSTLDEAKERLRFLMIRKYTRTLLILDDVWDSTVLKAVDIHCRILLTTRNRSLADVVNGSKHEVEVNSGLDEDKALEILSQLSKIEMYRLPEEAL-SIVKKCQGSPLAVSMIGSLLRENPDRWGYYLRQLEKKQFRRIRKSSSYNYEALDQAIAAGIEDLSDDYRDLYNLLTVLHKDVKVTAKMMSVLWGQDQVDTEDTLSEFVNRAMLFV--DSQSQPNVFYLHDLQLDFLLEQNKNQLKSLHKKMVERYQHRYKDRPLTSRDEESLYWIRYLAYHMANANLFQELHSLLFSLDWISVKGQIMGPAHLINDYLEYGSILDKENNEMCSEFQEFLSLSGHYLEQRP------------FPDIVQLALSQPHTSEVYRQARLLAQERAKDGKLYFDLINETSVDSLSRLVIHPHQGSLYACFSNDGTKIASCGATKNLKVFKS----------TSGEKLSEFELRDEVVCCAFSPDDSLLAVCSSG 674
[Close]
BLAST of apaf1 vs. Ensembl Cavefish
Match: apaf1 (apoptotic peptidase activating factor 1 [Source:NCBI gene;Acc:58131])

HSP 1 Score: 67.3958 bits (163), Expect = 5.107e-11
Identity = 109/501 (21.76%), Postives = 208/501 (41.52%), Query Frame = 3 
Query:  399 ILIKGGVPDRNVDYVPRPNLENIILNAIISNKKMP--ILIHGIIGCGKTSIVSNLLHSDQLFPYRFLTCC-WMDVGNIEEKDIXXXXXX------XXXXXDPSPQLP--------------LNIIPEILVDRIKAKLYDGTTXXXXXXXXXXXXXXXXXXXXTYIVVSRQSNLVPDSTAKLINIP--DGFEIEECRSLMKHY-NISEDLFPK----IISKSMKNPLSLSMICKLVHSNGD----YIRMLNEKSFNS---------NHLDKIVQGYIKVLDDELKSKYEMLAIXXXXXXXXXXXXXYYWNVSYVKALDMVNKLCDFNLLHKTWNSTFNINLYGVYDIYLKYL-QQNVTNLQKFKQIFIDNYEAKYKKW----LDVKEPDPFFLIFYGKTLFYNKNDEKLIELYTDFSFIAAKIVICGIIYLQNEYEKYKP--SDFNSDWD-DFEAFFIKYSHKFMKIPSACKIPTKIGKVFINLIQLALYEPKTSATYKFAM 1748
            IL +GGVP R + +V RP L N +   +   +K+   + + G+ G GK+ + +  +    L    F     W+ VG  E  ++  ++ S          +D +P+ P              L   P  L+  I   ++D ++L   D                 ++ +R  +L    + +  ++P   G + E+   ++  Y N      P+    I+ +   +PL +S+I  L+    D    Y+R L  K F             LD+ +   ++VL+DE +  Y+ L++LE D  +  ++LS  W++   +  D++ +  + +LL +  N      +Y ++D+ L +L +QN + L +     +  Y+  Y K      DV+    ++  F    +      ++L  L     ++  K  I G  +L N+Y ++       NS+    F+ F     H+  + P            F +L+QLAL +P  S  Y+ A+
Sbjct:  113 ILSEGGVPQRPMVFVNRPALLNQVREKLYQLQKVVGWVTVFGMAGSGKSVLAAEAVRDHSLIKECFPDGVHWLSVGQCERAELLVRMQSLCFRLEQNQTVDSTPRPPNSIEEAKERLRFLMLRKFPRALL--ILDDVWDSSSLRAFDIQCR------------VLLTTRNRSLTDSVSGQKESVPVESGLDEEKALEILALYVNAQLHSLPEQAHCIVKECKGSPLVVSLIGALLREFPDRWGYYLRQLQRKQFQRIRKSSSYDYEALDQAMDASLQVLNDEHRELYKDLSVLEKDVKVPAKVLSVLWDLELEEVEDVLQEFVNKSLLFRDCNQ--RPYMYFLHDLQLDFLTEQNRSQLAELHGKVVRQYQQAYAKGPPTSADVE--GLYWYRFLPHHIARAGLSKELYSLMFSLDWVKNKAQIMGSAHLINDYVEHGAILDQENSEVRLQFQEFLSLNGHQLEQRP------------FPDLVQLALSQPHCSEVYRQAL 583
[Close]
BLAST of apaf1 vs. Ensembl Cavefish
Match: apaf1 (apoptotic peptidase activating factor 1 [Source:NCBI gene;Acc:58131])

HSP 1 Score: 67.3958 bits (163), Expect = 5.716e-11
Identity = 109/501 (21.76%), Postives = 208/501 (41.52%), Query Frame = 3 
Query:  399 ILIKGGVPDRNVDYVPRPNLENIILNAIISNKKMP--ILIHGIIGCGKTSIVSNLLHSDQLFPYRFLTCC-WMDVGNIEEKDIXXXXXX------XXXXXDPSPQLP--------------LNIIPEILVDRIKAKLYDGTTXXXXXXXXXXXXXXXXXXXXTYIVVSRQSNLVPDSTAKLINIP--DGFEIEECRSLMKHY-NISEDLFPK----IISKSMKNPLSLSMICKLVHSNGD----YIRMLNEKSFNS---------NHLDKIVQGYIKVLDDELKSKYEMLAIXXXXXXXXXXXXXYYWNVSYVKALDMVNKLCDFNLLHKTWNSTFNINLYGVYDIYLKYL-QQNVTNLQKFKQIFIDNYEAKYKKW----LDVKEPDPFFLIFYGKTLFYNKNDEKLIELYTDFSFIAAKIVICGIIYLQNEYEKYKP--SDFNSDWD-DFEAFFIKYSHKFMKIPSACKIPTKIGKVFINLIQLALYEPKTSATYKFAM 1748
            IL +GGVP R + +V RP L N +   +   +K+   + + G+ G GK+ + +  +    L    F     W+ VG  E  ++  ++ S          +D +P+ P              L   P  L+  I   ++D ++L   D                 ++ +R  +L    + +  ++P   G + E+   ++  Y N      P+    I+ +   +PL +S+I  L+    D    Y+R L  K F             LD+ +   ++VL+DE +  Y+ L++LE D  +  ++LS  W++   +  D++ +  + +LL +  N      +Y ++D+ L +L +QN + L +     +  Y+  Y K      DV+    ++  F    +      ++L  L     ++  K  I G  +L N+Y ++       NS+    F+ F     H+  + P            F +L+QLAL +P  S  Y+ A+
Sbjct:  113 ILSEGGVPQRPMVFVNRPALLNQVREKLYQLQKVVGWVTVFGMAGSGKSVLAAEAVRDHSLIKECFPDGVHWLSVGQCERAELLVRMQSLCFRLEQNQTVDSTPRPPNSIEEAKERLRFLMLRKFPRALL--ILDDVWDSSSLRAFDIQCR------------VLLTTRNRSLTDSVSGQKESVPVESGLDEEKALEILALYVNAQLHSLPEQAHCIVKECKGSPLVVSLIGALLREFPDRWGYYLRQLQRKQFQRIRKSSSYDYEALDQAMDASLQVLNDEHRELYKDLSVLEKDVKVPAKVLSVLWDLELEEVEDVLQEFVNKSLLFRDCNQ--RPYMYFLHDLQLDFLTEQNRSQLAELHGKVVRQYQQAYAKGPPTSADVE--GLYWYRFLPHHIARAGLSKELYSLMFSLDWVKNKAQIMGSAHLINDYVEHGAILDQENSEVRLQFQEFLSLNGHQLEQRP------------FPDLVQLALSQPHCSEVYRQAL 583
[Close]
BLAST of apaf1 vs. Ensembl Cavefish
Match: apaf1 (apoptotic peptidase activating factor 1 [Source:NCBI gene;Acc:58131])

HSP 1 Score: 67.3958 bits (163), Expect = 5.716e-11
Identity = 109/501 (21.76%), Postives = 208/501 (41.52%), Query Frame = 3 
Query:  399 ILIKGGVPDRNVDYVPRPNLENIILNAIISNKKMP--ILIHGIIGCGKTSIVSNLLHSDQLFPYRFLTCC-WMDVGNIEEKDIXXXXXX------XXXXXDPSPQLP--------------LNIIPEILVDRIKAKLYDGTTXXXXXXXXXXXXXXXXXXXXTYIVVSRQSNLVPDSTAKLINIP--DGFEIEECRSLMKHY-NISEDLFPK----IISKSMKNPLSLSMICKLVHSNGD----YIRMLNEKSFNS---------NHLDKIVQGYIKVLDDELKSKYEMLAIXXXXXXXXXXXXXYYWNVSYVKALDMVNKLCDFNLLHKTWNSTFNINLYGVYDIYLKYL-QQNVTNLQKFKQIFIDNYEAKYKKW----LDVKEPDPFFLIFYGKTLFYNKNDEKLIELYTDFSFIAAKIVICGIIYLQNEYEKYKP--SDFNSDWD-DFEAFFIKYSHKFMKIPSACKIPTKIGKVFINLIQLALYEPKTSATYKFAM 1748
            IL +GGVP R + +V RP L N +   +   +K+   + + G+ G GK+ + +  +    L    F     W+ VG  E  ++  ++ S          +D +P+ P              L   P  L+  I   ++D ++L   D                 ++ +R  +L    + +  ++P   G + E+   ++  Y N      P+    I+ +   +PL +S+I  L+    D    Y+R L  K F             LD+ +   ++VL+DE +  Y+ L++LE D  +  ++LS  W++   +  D++ +  + +LL +  N      +Y ++D+ L +L +QN + L +     +  Y+  Y K      DV+    ++  F    +      ++L  L     ++  K  I G  +L N+Y ++       NS+    F+ F     H+  + P            F +L+QLAL +P  S  Y+ A+
Sbjct:  113 ILSEGGVPQRPMVFVNRPALLNQVREKLYQLQKVVGWVTVFGMAGSGKSVLAAEAVRDHSLIKECFPDGVHWLSVGQCERAELLVRMQSLCFRLEQNQTVDSTPRPPNSIEEAKERLRFLMLRKFPRALL--ILDDVWDSSSLRAFDIQCR------------VLLTTRNRSLTDSVSGQKESVPVESGLDEEKALEILALYVNAQLHSLPEQAHCIVKECKGSPLVVSLIGALLREFPDRWGYYLRQLQRKQFQRIRKSSSYDYEALDQAMDASLQVLNDEHRELYKDLSVLEKDVKVPAKVLSVLWDLELEEVEDVLQEFVNKSLLFRDCNQ--RPYMYFLHDLQLDFLTEQNRSQLAELHGKVVRQYQQAYAKGPPTSADVE--GLYWYRFLPHHIARAGLSKELYSLMFSLDWVKNKAQIMGSAHLINDYVEHGAILDQENSEVRLQFQEFLSLNGHQLEQRP------------FPDLVQLALSQPHCSEVYRQAL 583
[Close]
BLAST of apaf1 vs. Ensembl Nematostella
Match: EDO47633 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RLM8])

HSP 1 Score: 92.8189 bits (229), Expect = 2.871e-19
Identity = 141/615 (22.93%), Postives = 267/615 (43.41%), Query Frame = 3 
Query:  129 DILEDVIPTDIIPDLRSCKLFTLEDEQIVLHEITDKAKNRKLLDIIKSRPDELYEKFCEILRITNEDVAENLESHDYTRTRRVSNTDFGD-----ILIKGGVPDRNVDYVPRPNLENIILNAIISNKKMP--ILIHGIIGCGKTSIVSNLLHS----DQLFPYRFLTCCWMDVGNIEEKDIXXXXX--XXXXXXDPSPQLPLNIIPEILVDRIK---AKLYDGTTXXXXXXXXXXXXXXXXXXXXTYIVVSRQSNL---VPDSTAKLINIPDGFEIEECRSLMKHYNISEDLFP---KIISKSMKNPLSLSMICKLVHSNGD----YIRMLNEK---------SFNSNHLDKIVQGYIKVLDDELKSKYEMLAIXXXXXXXXXXXXXYYWNVSYVKALDMVNKLCDFNLLHKTWNSTFNINL-YGVYDIYLKYLQQNVTNLQKFKQIFIDNYEAKYKKW---LDVKEPDPFFLIFYGKTLFYNKNDEKLIELYTDFSFIAAKIVICGIIYLQNEYEKYKPSDFNSDW----------------DDFEAFFIKYSHKFMKIPSACKIPTKIGKVFINLIQLALYEPKTSATYKFAMSCKN--KCNWKDFWEWTNPR 1802
            DI  D++  D++P L+S  +  L D++ +  E T K K ++LLDI+ ++  + +E F  IL      +   L S        VS+  +GD     +L++GGVP R   +  R    + +  A+ S K+    +++HG+ GCGKT + +  L S    DQLFP       W+ +G++ +  +  ++    +    D S   P N+  E   DR++   A  Y  + L++ D     ++ +      T +V +R +++   V  S  K + + +GF  +E   ++  +  + DL P   K+++    +PL++SMI  ++  + +    Y+    +K         ++    L + +   I  L +E+++ Y   A+ +D   +  ++L   W+       D++++L + +L  K   S   + + Y ++++ L +LQ+  T+        ID Y   Y       DV E D +      + +      E    L T  S++ +K+ + G            PSD  SD+                D+F  F    +H F            + K+  +++QLAL +P  S  +  AM+  +      K + EW N R
Sbjct:   15 DISRDLLVDDVLPYLQSKLVLDLYDKECIYVEKTSKKKAQRLLDILPTKGFDAFEHFFTILGEKYPQLVGLLRSG-------VSDETYGDAIDSNVLLEGGVPQRPDIFTNRARDVHKVRTALRSLKEHDGWVILHGMAGCGKTVLAAEALRSPGLLDQLFPGGVF---WIRIGSVSQAKLLMQMQNLCVRLDHDHSRAPPRNL--EEAKDRLRMLFAHQYPRSLLVLDDLWNAADVKYFDIRCRT-LVTTRDASITDSVGGSKVK-VRVSEGFSDKEALQILSLWTRTFDLPPEAIKLVNLCNGSPLAISMIGAMLKEHPNRWKYYLNQFQKKKVSKLKTKFAYEYPSLSEAILMGINNLSEEMRTYYIDFALFDDGSKVPAQVLCILWDEELEIVEDLMDELVNKSLARKCVQSQDALGISYSIHNLQLAFLQELSTDKVALHAKIIDRYRDVYGGTGGKFDVMEDDHYIHWNLIRHMLKANMVEDTYTLITSLSWVVSKLKVTG------------PSDVISDYISVRDSIKAEQELEVLDNFHHFVSTNAHLF------------VAKMMPDIVQLALQQPSLSQVHTQAMAQASILTKQGKMYIEWCNQR 591
[Close]
BLAST of apaf1 vs. Ensembl Medaka
Match: apaf1 (apoptotic peptidase activating factor 1 [Source:NCBI gene;Acc:101158654])

HSP 1 Score: 108.227 bits (269), Expect = 1.256e-23
Identity = 160/695 (23.02%), Postives = 307/695 (44.17%), Query Frame = 3 
Query:   96 EYLRALAYNEDDILEDVI-PTDIIPDLRSCKLFTLEDEQIVLHEITDKAKNRKLLDIIKSRPDELYEKFCEILRITNEDVAENLESHDYTRTRRVSNTD--FGDILIKGGVPDRNVDYVPRPNLENIILNAIISNKKMP--ILIHGIIGCGKTSIVSNLLHSDQLFPYRFLTCC-WMDVGNIEEKDIXXXXXXXXXXXDPSPQLPLNIIPEILVDRIKAKLY------DGTTXXXXXXXXXXXXXXXXXXXXTYIVVSRQSNL--VPDSTAKLINIPDGF------EIEECRSLMKHYNISEDLFPKIISKSMKNPLSLSMICKLVHSNGD----YIRMLNEK---------SFNSNHLDKIVQGYIKVLDDELKSKYEMLAIXXXXXXXXXXXXXYYWNVSYVKALDMVNKLCDFNLLHKTWNSTFNINLYGVYDIYLKY-LQQNVTNLQKFKQIFIDNYEAKYK-KWLDVKEPDPFFLIFYGKTLFYNKND-EKLIELYTDFSFIAAKIVICGIIYLQNEYEKYKP---SDFNSDWDDFEAFFIKYSHKFMKIPSACKIPTKIGKVFINLIQLALYEPKTSATYKFA--MSCKNKCNWKDFWEWTNP--------------RNSIKVWEINHGDNITSFDVMKNLIIMSSDSNSMRLLEFSTGKCLLNFKLRNHILLVKFISDHEFIIIFENG 2015
            E  RA        LE+++ P  ++  + S +  T+E+E ++ ++ T + +   L+D++  + +  +  F   L     D   NL   D   T+  S++      +L +GGVP R   +V RP  EN I   +   +K P  + + G+ G GK+ + S  +   +L    F     W+ +G +++ D+  K+ +L  +L+ +        P   +D  K +L          TLLILD++W++ +L   + H   ++ +R  +L  V + +   + +  G       EI    S ++ Y + E+    I+ K   +PL++SMI  L+  N D    Y+R L +K         S+N   LD+ +   I+ L D+ +  Y +L +L  D  ++ +++S  W    V   D +++  +  +L    +S    N++ ++D+ L + L+QN   L+   +  ++ Y+ +YK + L  ++ +  + I Y      N N  ++L  L     +I+ K  I G  +L N+Y +Y      + N    +F+ F     H   + P            F +++QLAL +P TS  Y+ A  ++ +   + K +++  N               + S+     N G  I S    KNL +  S          ++G+ L  F+LR+ ++   F  D   + +  +G
Sbjct:    5 ERARACLLKSRHKLEEIMKPAYLMDHMISDEAITVEEEDMIANQNTKREQAAALVDLLLKKDNYSFRSFYNALLKEEYDELANLLKEDLPLTQFTSSSQCPVQTVLSEGGVPPRPEAFVHRPKEENEIREKLYKLQKQPGWVTVFGMAGSGKSVLASEAVRHKELIEECFPEGIHWVSIGRLDKPDLLAKIQTLCFRLEQNLDSQQFHRPPSTLDEAKERLRFLMIRKYTRTLLILDDVWDSTVLKAVDIHCRILLTTRNRSLADVVNGSKHEVEVNSGLDEDKALEILSQLSKIEMYRLPEEAL-SIVKKCQGSPLAVSMIGSLLRENPDRWGYYLRQLEKKQFRRIRKSSSYNYEALDQAIAAGIEDLSDDYRDLYNLLTVLHKDVKVTAKMMSVLWGQDQVDTEDTLSEFVNRAMLFV--DSQSQPNVFYLHDLQLDFLLEQNKNQLKSLHKKMVERYQHRYKDRPLTSRDEESLYWIRYLAYHMANANLFQELHSLLFSLDWISVKGQIMGPAHLINDYLEYGSILDKENNEMCSEFQEFLSLSGHYLEQRP------------FPDIVQLALSQPHTSEVYRQARLLAQERAKDGKLYFDLINETSVDSLSRLVIHPHQGSLYACFSNDGTKIASCGATKNLKVFKS----------TSGEKLSEFELRDEVVCCAFSPDDSLLAVCSSG 674
[Close]
BLAST of apaf1 vs. Planmine SMEST
Match: SMESG000063172.1 (SMESG000063172.1)

HSP 1 Score: 1195.65 bits (3092), Expect = 0.000e+0
Identity = 635/647 (98.15%), Postives = 640/647 (98.92%), Query Frame = 3 
Query:   84 MNNTEYLRALAYNEDDILEDVIPTDIIPDLRSCKLFTLEDEQIVLHEITDKAKNRKLLDIIKSRPDELYEKFCEILRITNEDVAENLESHDYTRTRRVSNTDFGDILIKGGVPDRNVDYVPRPNLENIILNAIISNKKMPILIHGIIGCGKTSIVSNLLHSDQLFPYRFLTCCWMDVGNIEEKDIXXXXXXXXXXXDPSPQLPLNIIPEILVDRIKAKLYDGTTXXXXXXXXXXXXXXXXXXXXTYIVVSRQSNLVPDSTAKLINIPDGFEIEECRSLMKHYNISEDLFPKIISKSMKNPLSLSMICKLVHSNGDYIRMLNEKSFNSNHLDKIVQGYIKVLDDELKSKYEMLAIXXXXXXXXXXXXXYYWNVSYVKALDMVNKLCDFNLLHKTWNSTFNINLYGVYDIYLKYLQQNVTNLQKFKQIFIDNYEAKYKKWLDVKEPDPFFLIFYGKTLFYNKNDEKLIELYTDFSFIAAKIVICGIIYLQNEYEKYKPSDFNSDWDDFEAFFIKYSHKFMKIPSACKIPTKIGKVFINLIQLALYEPKTSATYKFAMSCKNKCNWKDFWEWTNPRNSIKVWEINHGDNITSFDVMKNLIIMSSDSNSMRLLEFSTGKCLLNFKLRNHILLVKFISDHEFIIIFENGEFW 2024
            MNNTEYLRALAYNEDDILEDVIPTDIIPDLRSCKLFTLEDEQIVLHEITDKAKNRKLLDIIKSRPDELYEKFCEILRITNED+AENLESH+YTRTRRVSNT+FGDILIKGGVPDRN DYV RPNLEN ILNAIISNKKMPILIHGIIGCGKTSIVSNLLHSDQLFPYRFLTCCWMDVGNIEEKDINNKLLSLLNKLDPSPQLPLNIIPEILVDRIKAKLYDGTTLLILDNIWNNNIL HFNFHNTYIVVSRQSNLV DSTAKLINIPDGFEIEECRSLMKHY+ISEDLFPKIISKSMKNPLSLSMICKLVHSN DYIRMLNEKSFNSNHLDKIVQGYIKVLDDELKSKYEMLAILEDDETLSLELLSYYWNVSYVKALDMVNKLCDFNLLHKTWNSTFNINLYGVYDIYLKYLQQNVTN+QKFKQIFIDNYEAKYKKWLDVKEPDPFFLIFYGKTLFYNKNDEKLIELYTDFSFIAAKIVICGIIYLQNEYEKYKPSDFNSDWDDFEAFFIKYSHKFMKIPSA KIPTKIGKVFINLIQLALYEPKTSATYKFAMSCKNKCNWKDFWEWTNPRNSIKVWEINHGDNITSFDVMKNLIIMSSDSNSMRLLEFSTGKCLLNFKLRNHILLVKFISDHEFIIIFENGEFW
Sbjct:    1 MNNTEYLRALAYNEDDILEDVIPTDIIPDLRSCKLFTLEDEQIVLHEITDKAKNRKLLDIIKSRPDELYEKFCEILRITNEDIAENLESHNYTRTRRVSNTEFGDILIKGGVPDRNDDYVRRPNLENTILNAIISNKKMPILIHGIIGCGKTSIVSNLLHSDQLFPYRFLTCCWMDVGNIEEKDINNKLLSLLNKLDPSPQLPLNIIPEILVDRIKAKLYDGTTLLILDNIWNNNILQHFNFHNTYIVVSRQSNLVLDSTAKLINIPDGFEIEECRSLMKHYDISEDLFPKIISKSMKNPLSLSMICKLVHSNEDYIRMLNEKSFNSNHLDKIVQGYIKVLDDELKSKYEMLAILEDDETLSLELLSYYWNVSYVKALDMVNKLCDFNLLHKTWNSTFNINLYGVYDIYLKYLQQNVTNIQKFKQIFIDNYEAKYKKWLDVKEPDPFFLIFYGKTLFYNKNDEKLIELYTDFSFIAAKIVICGIIYLQNEYEKYKPSDFNSDWDDFEAFFIKYSHKFMKIPSAYKIPTKIGKVFINLIQLALYEPKTSATYKFAMSCKNKCNWKDFWEWTNPRNSIKVWEINHGDNITSFDVMKNLIIMSSDSNSMRLLEFSTGKCLLNFKLRNHILLVKFISDHEFIIIFENGEFW 647
[Close]
BLAST of apaf1 vs. Planmine SMEST
Match: SMESG000063172.1 (SMESG000063172.1)

HSP 1 Score: 1192.95 bits (3085), Expect = 0.000e+0
Identity = 635/647 (98.15%), Postives = 640/647 (98.92%), Query Frame = 3 
Query:   84 MNNTEYLRALAYNEDDILEDVIPTDIIPDLRSCKLFTLEDEQIVLHEITDKAKNRKLLDIIKSRPDELYEKFCEILRITNEDVAENLESHDYTRTRRVSNTDFGDILIKGGVPDRNVDYVPRPNLENIILNAIISNKKMPILIHGIIGCGKTSIVSNLLHSDQLFPYRFLTCCWMDVGNIEEKDIXXXXXXXXXXXDPSPQLPLNIIPEILVDRIKAKLYDGTTXXXXXXXXXXXXXXXXXXXXTYIVVSRQSNLVPDSTAKLINIPDGFEIEECRSLMKHYNISEDLFPKIISKSMKNPLSLSMICKLVHSNGDYIRMLNEKSFNSNHLDKIVQGYIKVLDDELKSKYEMLAIXXXXXXXXXXXXXYYWNVSYVKALDMVNKLCDFNLLHKTWNSTFNINLYGVYDIYLKYLQQNVTNLQKFKQIFIDNYEAKYKKWLDVKEPDPFFLIFYGKTLFYNKNDEKLIELYTDFSFIAAKIVICGIIYLQNEYEKYKPSDFNSDWDDFEAFFIKYSHKFMKIPSACKIPTKIGKVFINLIQLALYEPKTSATYKFAMSCKNKCNWKDFWEWTNPRNSIKVWEINHGDNITSFDVMKNLIIMSSDSNSMRLLEFSTGKCLLNFKLRNHILLVKFISDHEFIIIFENGEFW 2024
            MNNTEYLRALAYNEDDILEDVIPTDIIPDLRSCKLFTLEDEQIVLHEITDKAKNRKLLDIIKSRPDELYEKFCEILRITNED+AENLESH+YTRTRRVSNT+FGDILIKGGVPDRN DYV RPNLEN ILNAIISNKKMPILIHGIIGCGKTSIVSNLLHSDQLFPYRFLTCCWMDVGNIEEKDINNKLLSLLNKLDPSPQLPLNIIPEILVDRIKAKLYDGTTLLILDNIWNNNIL HFNFHNTYIVVSRQSNLV DSTAKLINIPDGFEIEECRSLMKHY+ISEDLFPKIISKSMKNPLSLSMICKLVHSN DYIRMLNEKSFNSNHLDKIVQGYIKVLDDELKSKYEMLAILEDDETLSLELLSYYWNVSYVKALDMVNKLCDFNLLHKTWNSTFNINLYGVYDIYLKYLQQNVTN+QKFKQIFIDNYEAKYKKWLDVKEPDPFFLIFYGKTLFYNKNDEKLIELYTDFSFIAAKIVICGIIYLQNEYEKYKPSDFNSDWDDFEAFFIKYSHKFMKIPSA KIPTKIGKVFINLIQLALYEPKTSATYKFAMSCKNKCNWKDFWEWTNPRNSIKVWEINHGDNITSFDVMKNLIIMSSDSNSMRLLEFSTGKCLLNFKLRNHILLVKFISDHEFIIIFENGEFW
Sbjct:    1 MNNTEYLRALAYNEDDILEDVIPTDIIPDLRSCKLFTLEDEQIVLHEITDKAKNRKLLDIIKSRPDELYEKFCEILRITNEDIAENLESHNYTRTRRVSNTEFGDILIKGGVPDRNDDYVRRPNLENTILNAIISNKKMPILIHGIIGCGKTSIVSNLLHSDQLFPYRFLTCCWMDVGNIEEKDINNKLLSLLNKLDPSPQLPLNIIPEILVDRIKAKLYDGTTLLILDNIWNNNILQHFNFHNTYIVVSRQSNLVLDSTAKLINIPDGFEIEECRSLMKHYDISEDLFPKIISKSMKNPLSLSMICKLVHSNEDYIRMLNEKSFNSNHLDKIVQGYIKVLDDELKSKYEMLAILEDDETLSLELLSYYWNVSYVKALDMVNKLCDFNLLHKTWNSTFNINLYGVYDIYLKYLQQNVTNIQKFKQIFIDNYEAKYKKWLDVKEPDPFFLIFYGKTLFYNKNDEKLIELYTDFSFIAAKIVICGIIYLQNEYEKYKPSDFNSDWDDFEAFFIKYSHKFMKIPSAYKIPTKIGKVFINLIQLALYEPKTSATYKFAMSCKNKCNWKDFWEWTNPRNSIKVWEINHGDNITSFDVMKNLIIMSSDSNSMRLLEFSTGKCLLNFKLRNHILLVKFISDHEFIIIFENGEFW 647
[Close]
BLAST of apaf1 vs. Planmine SMEST
Match: SMESG000063172.1 (SMESG000063172.1)

HSP 1 Score: 1192.18 bits (3083), Expect = 0.000e+0
Identity = 635/647 (98.15%), Postives = 640/647 (98.92%), Query Frame = 3 
Query:   84 MNNTEYLRALAYNEDDILEDVIPTDIIPDLRSCKLFTLEDEQIVLHEITDKAKNRKLLDIIKSRPDELYEKFCEILRITNEDVAENLESHDYTRTRRVSNTDFGDILIKGGVPDRNVDYVPRPNLENIILNAIISNKKMPILIHGIIGCGKTSIVSNLLHSDQLFPYRFLTCCWMDVGNIEEKDIXXXXXXXXXXXDPSPQLPLNIIPEILVDRIKAKLYDGTTXXXXXXXXXXXXXXXXXXXXTYIVVSRQSNLVPDSTAKLINIPDGFEIEECRSLMKHYNISEDLFPKIISKSMKNPLSLSMICKLVHSNGDYIRMLNEKSFNSNHLDKIVQGYIKVLDDELKSKYEMLAIXXXXXXXXXXXXXYYWNVSYVKALDMVNKLCDFNLLHKTWNSTFNINLYGVYDIYLKYLQQNVTNLQKFKQIFIDNYEAKYKKWLDVKEPDPFFLIFYGKTLFYNKNDEKLIELYTDFSFIAAKIVICGIIYLQNEYEKYKPSDFNSDWDDFEAFFIKYSHKFMKIPSACKIPTKIGKVFINLIQLALYEPKTSATYKFAMSCKNKCNWKDFWEWTNPRNSIKVWEINHGDNITSFDVMKNLIIMSSDSNSMRLLEFSTGKCLLNFKLRNHILLVKFISDHEFIIIFENGEFW 2024
            MNNTEYLRALAYNEDDILEDVIPTDIIPDLRSCKLFTLEDEQIVLHEITDKAKNRKLLDIIKSRPDELYEKFCEILRITNED+AENLESH+YTRTRRVSNT+FGDILIKGGVPDRN DYV RPNLEN ILNAIISNKKMPILIHGIIGCGKTSIVSNLLHSDQLFPYRFLTCCWMDVGNIEEKDINNKLLSLLNKLDPSPQLPLNIIPEILVDRIKAKLYDGTTLLILDNIWNNNIL HFNFHNTYIVVSRQSNLV DSTAKLINIPDGFEIEECRSLMKHY+ISEDLFPKIISKSMKNPLSLSMICKLVHSN DYIRMLNEKSFNSNHLDKIVQGYIKVLDDELKSKYEMLAILEDDETLSLELLSYYWNVSYVKALDMVNKLCDFNLLHKTWNSTFNINLYGVYDIYLKYLQQNVTN+QKFKQIFIDNYEAKYKKWLDVKEPDPFFLIFYGKTLFYNKNDEKLIELYTDFSFIAAKIVICGIIYLQNEYEKYKPSDFNSDWDDFEAFFIKYSHKFMKIPSA KIPTKIGKVFINLIQLALYEPKTSATYKFAMSCKNKCNWKDFWEWTNPRNSIKVWEINHGDNITSFDVMKNLIIMSSDSNSMRLLEFSTGKCLLNFKLRNHILLVKFISDHEFIIIFENGEFW
Sbjct:    1 MNNTEYLRALAYNEDDILEDVIPTDIIPDLRSCKLFTLEDEQIVLHEITDKAKNRKLLDIIKSRPDELYEKFCEILRITNEDIAENLESHNYTRTRRVSNTEFGDILIKGGVPDRNDDYVRRPNLENTILNAIISNKKMPILIHGIIGCGKTSIVSNLLHSDQLFPYRFLTCCWMDVGNIEEKDINNKLLSLLNKLDPSPQLPLNIIPEILVDRIKAKLYDGTTLLILDNIWNNNILQHFNFHNTYIVVSRQSNLVLDSTAKLINIPDGFEIEECRSLMKHYDISEDLFPKIISKSMKNPLSLSMICKLVHSNEDYIRMLNEKSFNSNHLDKIVQGYIKVLDDELKSKYEMLAILEDDETLSLELLSYYWNVSYVKALDMVNKLCDFNLLHKTWNSTFNINLYGVYDIYLKYLQQNVTNIQKFKQIFIDNYEAKYKKWLDVKEPDPFFLIFYGKTLFYNKNDEKLIELYTDFSFIAAKIVICGIIYLQNEYEKYKPSDFNSDWDDFEAFFIKYSHKFMKIPSAYKIPTKIGKVFINLIQLALYEPKTSATYKFAMSCKNKCNWKDFWEWTNPRNSIKVWEINHGDNITSFDVMKNLIIMSSDSNSMRLLEFSTGKCLLNFKLRNHILLVKFISDHEFIIIFENGEFW 647
The following BLAST results are available for this feature:
BLAST of apaf1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
APAF11.810e-1623.21apoptotic peptidase activating factor 1 [Source:HG... [more]
APAF12.071e-1623.21apoptotic peptidase activating factor 1 [Source:HG... [more]
APAF11.163e-1523.15apoptotic peptidase activating factor 1 [Source:HG... [more]
APAF11.263e-1523.15apoptotic peptidase activating factor 1 [Source:HG... [more]
APAF11.263e-1523.15apoptotic peptidase activating factor 1 [Source:HG... [more]
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BLAST of apaf1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of apaf1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of apaf1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 2
Match NameE-valueIdentityDescription
apaf13.180e-622.05apoptotic peptidase activating factor 1 [Source:NC... [more]
apaf16.496e-622.11apoptotic peptidase activating factor 1 [Source:NC... [more]
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BLAST of apaf1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of apaf1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 3
Match NameE-valueIdentityDescription
Apaf18.626e-1421.98apoptotic peptidase activating factor 1 [Source:MG... [more]
Apaf15.499e-1321.93apoptotic peptidase activating factor 1 [Source:MG... [more]
Apaf15.499e-1321.93apoptotic peptidase activating factor 1 [Source:MG... [more]
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BLAST of apaf1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 3
Match NameE-valueIdentityDescription
sp|O14727|APAF_HUMAN8.011e-1523.15Apoptotic protease-activating factor 1 OS=Homo sap... [more]
sp|O88879|APAF_MOUSE3.847e-1221.93Apoptotic protease-activating factor 1 OS=Mus musc... [more]
sp|Q9EPV5|APAF_RAT8.189e-1121.94Apoptotic protease-activating factor 1 OS=Rattus n... [more]
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BLAST of apaf1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
H2DL110.000e+099.38Apaf1 OS=Schmidtea mediterranea OX=79327 PE=2 SV=1[more]
C3YZV63.804e-2521.65Uncharacterized protein OS=Branchiostoma floridae ... [more]
A0A2B4SA853.871e-2322.92Apoptotic protease-activating factor 1 OS=Stylopho... [more]
A0A3M6V2D92.673e-2024.71Uncharacterized protein OS=Pocillopora damicornis ... [more]
H2MKX53.336e-2023.02Apoptotic protease-activating factor 1 OS=Oryzias ... [more]
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BLAST of apaf1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 3
Match NameE-valueIdentityDescription
apaf15.107e-1121.76apoptotic peptidase activating factor 1 [Source:NC... [more]
apaf15.716e-1121.76apoptotic peptidase activating factor 1 [Source:NC... [more]
apaf15.716e-1121.76apoptotic peptidase activating factor 1 [Source:NC... [more]
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BLAST of apaf1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of apaf1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of apaf1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1
Match NameE-valueIdentityDescription
EDO476332.871e-1922.93Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of apaf1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 1
Match NameE-valueIdentityDescription
apaf11.256e-2323.02apoptotic peptidase activating factor 1 [Source:NC... [more]
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BLAST of apaf1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 3
Match NameE-valueIdentityDescription
SMESG000063172.10.000e+098.15SMESG000063172.1[more]
SMESG000063172.10.000e+098.15SMESG000063172.1[more]
SMESG000063172.10.000e+098.15SMESG000063172.1[more]
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Cross References
External references for this transcript
DatabaseAccession
SmedGD GBrowseSMED30009849
GenBankAEX93473.1
Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30009849 ID=SMED30009849|Name=apaf1|organism=Schmidtea mediterranea sexual|type=transcript|length=2446bp
TTTAAATTTAGTAATATCAGTGATTCATCGATATTAAATTTTACCAATAC
TAATATTATTTTTATATGAGTTTTTACATTTAAATGAATAACACTGAATA
TCTAAGAGCTCTTGCATATAATGAAGATGATATACTAGAAGATGTTATTC
CTACAGATATTATTCCTGATTTACGATCATGTAAATTGTTTACTTTAGAA
GATGAACAGATTGTTCTTCACGAGATTACGGATAAAGCTAAAAATAGAAA
ACTGTTAGATATAATTAAGAGCAGACCAGATGAATTATACGAAAAATTTT
GCGAAATATTGCGCATAACAAATGAGGATGTTGCTGAAAATTTAGAAAGT
CACGACTATACTCGAACTAGGCGTGTCAGCAATACAGATTTTGGCGACAT
TTTAATTAAAGGTGGAGTTCCGGATCGTAATGTTGATTATGTTCCGAGAC
CAAATTTAGAAAATATAATTTTAAATGCAATTATATCAAATAAAAAAATG
CCTATATTGATTCATGGAATAATTGGCTGTGGTAAAACTAGTATAGTGTC
AAATCTTCTTCATTCCGATCAACTGTTTCCGTATCGATTTCTTACTTGTT
GTTGGATGGATGTAGGAAATATAGAAGAAAAAGATATTAATAATAAATTA
TTGAGTTTGTTAAACAAATTGGATCCATCTCCTCAATTGCCATTAAATAT
TATTCCGGAAATATTAGTCGATCGGATCAAGGCTAAATTGTACGACGGAA
CTACTTTATTAATTCTCGATAATATATGGAACAATAATATATTACATCAT
TTTAATTTTCACAATACGTATATTGTTGTCAGTAGGCAGTCAAATTTGGT
TCCGGATAGCACAGCAAAGCTAATTAACATACCAGATGGTTTTGAAATTG
AAGAATGTAGATCATTAATGAAACATTACAACATTTCAGAAGATTTATTT
CCAAAGATTATTTCTAAGTCTATGAAAAATCCATTATCGTTGTCAATGAT
TTGCAAGTTAGTACATTCAAATGGAGATTACATTCGAATGCTCAATGAGA
AGAGTTTTAATAGTAATCATTTAGATAAAATTGTACAAGGATATATTAAA
GTTCTTGATGATGAACTGAAATCAAAATATGAAATGTTAGCTATCCTTGA
GGATGATGAAACATTATCACTTGAGTTACTGTCATATTATTGGAATGTTA
GTTATGTCAAAGCACTGGACATGGTCAATAAATTATGTGATTTCAATCTT
CTTCACAAAACTTGGAATAGCACATTCAACATAAATTTATATGGTGTGTA
CGATATCTATTTAAAATATTTACAACAGAATGTAACCAATTTACAAAAAT
TTAAGCAGATTTTCATTGACAATTATGAAGCAAAATACAAAAAATGGCTT
GACGTTAAAGAACCTGATCCATTCTTCCTAATATTTTATGGAAAGACGTT
ATTTTATAACAAAAATGATGAAAAACTGATTGAATTATATACTGATTTTT
CATTTATAGCTGCTAAAATTGTTATTTGTGGAATTATATACTTGCAAAAC
GAATATGAAAAATACAAGCCATCGGATTTCAATTCTGATTGGGATGATTT
TGAAGCATTTTTCATAAAGTATAGTCATAAGTTTATGAAGATTCCATCAG
CTTGTAAAATACCTACAAAAATAGGGAAAGTATTTATAAATCTTATTCAA
TTAGCCTTATACGAGCCAAAAACCTCTGCAACATATAAATTCGCGATGAG
TTGTAAAAACAAATGCAATTGGAAAGATTTTTGGGAATGGACAAATCCAA
GAAATTCAATAAAAGTCTGGGAGATAAATCATGGAGATAATATAACGAGT
TTCGATGTAATGAAGAATTTGATAATCATGTCCAGTGATTCAAATAGTAT
GCGTCTTCTAGAATTTAGTACTGGGAAGTGCTTGTTAAATTTCAAATTAC
GAAATCATATTTTACTCGTGAAATTCATTAGCGATCACGAATTCATAATA
ATATTTGAAAATGGTGAATTTTGGTAAGAATTTTAATTAATTTTAATTTC
TTCAAACTTAAAATTTTCAAATTATATTAACACTAGAACTACCGTACCAA
TCAAAATTATCTAATTAATTAATTTTTTTCTGCTTAACTCTATTGAAGCC
AATGCGGTCAAATACGACCGCAACTTGTTAAAACGCGTCCACATTGAATA
AAATGCTCCCATCCAGTTCTATTTATAGCTCATTGATACAACTTGATGCA
CGTCTGATGAATCTAGTCAAAAGTTGTTTTTGTTTTGGAAGTTTTAGGAT
TATTTTTCGTTGTTTTTGAAGTGTTATTGTTGAAATCGGGACATTTACAT
TCCATGACAAATAGACGGAAGCCATTTCGAACAGCTGATGTCCTGAAAGC
TCTAGATACAACAGATAACAGCAACAATGAGAGAAGGAGCCTATGA
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protein sequence of SMED30009849-orf-1

>SMED30009849-orf-1 ID=SMED30009849-orf-1|Name=SMED30009849-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=648bp
MNNTEYLRALAYNEDDILEDVIPTDIIPDLRSCKLFTLEDEQIVLHEITD
KAKNRKLLDIIKSRPDELYEKFCEILRITNEDVAENLESHDYTRTRRVSN
TDFGDILIKGGVPDRNVDYVPRPNLENIILNAIISNKKMPILIHGIIGCG
KTSIVSNLLHSDQLFPYRFLTCCWMDVGNIEEKDINNKLLSLLNKLDPSP
QLPLNIIPEILVDRIKAKLYDGTTLLILDNIWNNNILHHFNFHNTYIVVS
RQSNLVPDSTAKLINIPDGFEIEECRSLMKHYNISEDLFPKIISKSMKNP
LSLSMICKLVHSNGDYIRMLNEKSFNSNHLDKIVQGYIKVLDDELKSKYE
MLAILEDDETLSLELLSYYWNVSYVKALDMVNKLCDFNLLHKTWNSTFNI
NLYGVYDIYLKYLQQNVTNLQKFKQIFIDNYEAKYKKWLDVKEPDPFFLI
FYGKTLFYNKNDEKLIELYTDFSFIAAKIVICGIIYLQNEYEKYKPSDFN
SDWDDFEAFFIKYSHKFMKIPSACKIPTKIGKVFINLIQLALYEPKTSAT
YKFAMSCKNKCNWKDFWEWTNPRNSIKVWEINHGDNITSFDVMKNLIIMS
SDSNSMRLLEFSTGKCLLNFKLRNHILLVKFISDHEFIIIFENGEFW*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: molecular function
TermDefinition
GO:0000166nucleotide binding
GO:0005524ATP binding
GO:0043531ADP binding
GO:0005515protein binding
GO:0008233peptidase activity
Vocabulary: cellular component
TermDefinition
GO:0005737cytoplasm
GO:0043293apoptosome
Vocabulary: biological process
TermDefinition
GO:0006915apoptotic process
GO:0097190apoptotic signaling pathway
GO:0042981regulation of apoptotic process
GO:0006508proteolysis
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000034epidermis
PLANA:0002032epidermal cell
Vocabulary: INTERPRO
TermDefinition
IPR036388WH-like_DNA-bd_sf
IPR041452APAF1_C
IPR036322WD40_repeat_dom_sf
IPR001315CARD
IPR011029DEATH-like_dom_sf
IPR002182NB-ARC
IPR015943WD40/YVTN_repeat-like_dom_sf
IPR027417P-loop_NTPase
IPR017986WD40_repeat_dom
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableGENE3DG3DSA:1.10.533.10coord: 3..94
e-value: 3.5E-15
score: 57.9
NoneNo IPR availableGENE3DG3DSA:3.40.50.300coord: 98..264
e-value: 4.8E-22
score: 80.3
NoneNo IPR availableGENE3DG3DSA:1.25.40.370coord: 418..562
e-value: 1.6E-12
score: 49.3
NoneNo IPR availablePANTHERPTHR22845:SF6APOPTOTIC PROTEASE-ACTIVATING FACTOR 1coord: 9..639
NoneNo IPR availablePANTHERPTHR22845FAMILY NOT NAMEDcoord: 9..639
NoneNo IPR availableCDDcd01671CARDcoord: 10..87
e-value: 9.51761E-17
score: 73.3196
IPR001315CARD domainPFAMPF00619CARDcoord: 15..89
e-value: 9.0E-12
score: 44.9
IPR001315CARD domainPROSITEPS50209CARDcoord: 1..91
score: 10.595
IPR036388Winged helix-like DNA-binding domain superfamilyGENE3DG3DSA:1.10.10.10coord: 333..417
e-value: 1.7E-9
score: 39.7
IPR002182NB-ARCPFAMPF00931NB-ARCcoord: 139..330
e-value: 5.0E-10
score: 39.0
IPR041452APAF-1 helical domainPFAMPF17908APAF1_Ccoord: 421..555
e-value: 2.6E-7
score: 30.7
IPR036322WD40-repeat-containing domain superfamilySUPERFAMILYSSF50978WD40 repeat-likecoord: 574..644
IPR011029Death-like domain superfamilySUPERFAMILYSSF47986DEATH domaincoord: 8..89
IPR027417P-loop containing nucleoside triphosphate hydrolaseSUPERFAMILYSSF52540P-loop containing nucleoside triphosphate hydrolasescoord: 103..346