Dach-2
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30009793 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 6
Homology
BLAST of Dach-2 vs. Ensembl Human
Match: MYO5A (myosin VA [Source:HGNC Symbol;Acc:HGNC:7602]) HSP 1 Score: 1108.98 bits (2867), Expect = 0.000e+0 Identity = 717/1905 (37.64%), Postives = 1089/1905 (57.17%), Query Frame = 2
Query: 47 MALYEMYSKGVKIWIPDEESVWIGATVLQFHKEKN-VIKIITDNGISKELNLSSK-KCAPFLRNPDILIGQKDLTYLSYLNEPEVLYNLQIRFCERREIYTYCGIVLVAINPYQELSIYGKEIINAYHSQNSVDLDPHIFAVAENAFRRMSSFGENQSIIVSGESGAGKTVSAKYTMRYFALVGGSKTKQSFNLTETQIERKVLLSNPILEAFGNAKTIRNDNSSRFGKYLEILFNPRNQVIGANMCTYLLEKSRVVFQNLGERNYHIFYQIVTHCQSEDELLMNTGLVNNVEMYDYLRYGESLEIDGVDDSHEFLITKNSFLQLGIDLNKFKTICEILAAILHLGNIRFRFHDATDSSIIENPELLKLIAGLLGCSIDQLKIWLCFRTISTFQETLHKPLSKAEAQYFRDAFVKTLYSNLFDWIVKQANKVLSTDVSINIKKKLKKTIVVNQEDKKKFIAVLDIYGFETFAENSFEQFCINFANEKLQLQFNLHVFKLEQEEYMNEGLEWTFIDYYNNQPCIDLIESRXXXXXXXXXXXXXXXXSDENWCCKIYSHHLNKSANFNKPKLSNMVFIIEHFAGPVEYKCAGFIEKNRDSVLEEQINLLKASDVQLIAELFRDSEIEIFDTNNXXXXXXXXXXXXXXXXXXQEN--TRKMKKTVGSQFRNSLKSLMDALNKTNPHYVRCIKPNDLKLPFTFCPERAVQQLRACGVLETIRLSAAGFPSRWTYSDFYHRYYILMSNFNVKNHDFKAGSQKIVETLITVPDAFRFGNTKLFFRPGQVALLEKLRGHKIESSVTLIQSILRGSIERKKYLIIHKLTVQIQTYIRRKLAIEKATKLSQIRAVIIIQSFYRMYLARKLFVKMKCAVLAIEKWRRKIITTRLKQAYKKENCVIICQAIVRRFIQRRKFLKIQRGVILIQNHYRRRKAKETLKILKIEARSINHIKFVNKGLENKIIELTQKLDTKEKEM-CXXXXXX--------XXXXXXXXXXXXXXXAESAKIYQNTVQDLQTEIIQLKKELNREIVEKNKI--FADKELLEINYKKKINYL-ENLIEE---LKSSPSVIEPNIICNGDEAQQSICQD--EHQKFI-----NEQMDHQKLVREYEKLEMKYENLYKEFLFVKSSNQKPSINYDNQTSNDSETESTFSKDDADVESLSDKVDAKTTKEHXXXXXXXXXXLPNFISESISTAGDLAVVMQLQMNISSLSQENNRLKETVQQFEDELLKYEQCAEDSKGLVIHNEYDNELLSIIKDIKGMDEHGLKSRLIDEVANLKKKL-KQSNEDYQKLRLHIFDGSMSKLTGNLDHESINSEEEELKRA-FESQKEANRK------------MLKEIEGIKANNVDLKKALFQIRKDKEQLQVQLGKQHLMIRHGVEYL----QNLK---------------LTPKERLDKFVQNEISRILLENLKLQERNDQIISETIELKRGLKYFAFRLQKYEGSLVPNPNKEEDLLQLIQNVIYHSKMKTIGKRECYSEIGLIDLNMSELSIFIKSFIFDLSP-SICLQYEPYHLVPYIIFMVTRKFDFYKEEDQMTNFLSKLIVALKRTIRKRRNYIEYLVMLLSNVFCLVNLXXXXXXXXXXXXLNTAEDIQHYFVHYDLNEFIRLLKELCVTLFQMILKTIVDNLLPQSLCIDAILVHEAI--IDFLSKDGTKYKSNIETQPKNTSFNVLTKNLQSVLEILKNHKIPQLIINQIFVHIAYLINAYCLNTLLFRTDLCYFSKGLQIKYNLSSFETWIRYQKLIDSGALQCLRPMTEAVQLLQTLIDSDEDAKFVCDMCEYLNTRQVVKILNNFNPRDGYGCRLSSGLIAKIETQMKIKRGDEPSESKLETPTVIEIPIDIPFIHNGVSLCRTIIPKPLYLSCLT 5575
MA E+Y+K ++WIPD E VW A +L+ +K + V+ + + G E +L K K P LRNPDIL+G+ DLT LSYL+EP VL+NL++RF + + IYTYCGIVLVAINPY++L IYG++IINAY QN D+DPHIFAVAE A+++M+ NQSIIVSGESGAGKTVSAKY MRYFA V GS +E +E KVL SNPI+E+ GNAKT RNDNSSRFGKY+EI F+ R ++IGANM TYLLEKSRVVFQ ERNYHIFYQ+ + + ++ G N + ++Y + G S I+GVDD+ E T+ + LGI + I ILA ILHLGN+ F DA +I E L + L+G +++ WLC R ++T ET KP+SK +A RDA K +Y+ LF+WIV N+ L + V + FI VLDIYGFETF NSFEQFCIN+ANEKLQ QFN+HVFKLEQEEYM E + WT ID+Y+NQPCI+LIES+LG+LDLLDEECK+ KG+D+ W K+Y+ HLNK A F KP+LSN FII+HFA VEY+C GF+EKN+D+V EEQI +LK+S +++ ELF+D E I T+ + + + T + + + ++ KKTVG QFRNSL LM+ LN T PHYVRCIKPND K PFTF +RAVQQLRACGVLETIR+SAAGFPSRWTY +F+ RY +LM +V + D K + ++E LI D ++FG TK+FFR GQVA LEKLR K+ ++ IQ +RG + RKKYL + K + +Q Y+R A A L + +A IIQ ++RMY+ R+ + + A + ++ + R + + +E+ +I Q VR ++ R + + +I +Q +RR AK LK LKIEARS+ K ++ G+ENKI++L +K+D + K+ CL++ EK L E AK+ V LQ EI +L+K+L + EK I AD+ YK++ L NL EE LK + I+ E +++ + E K + +E++ +Q L+ E+ +LE +Y++L KE + + KP + T + +E+E FS + A++E + + + + K+ D+++ ++LQ ++ L QE +++ + + E+++L+ + E+ + + E + E L K + +L +E+ L+K L ++S + + M +LT + + EE + R+ SQKEA + +L++++ +K + ++ +A +++ L+ QL Q + E L Q+LK L P+ R++ +Q+EI+R+ ENL L E+ ++ +LK+ LK FA ++ + E + N + + + + I+ V K K G+++ + +K+ I +L P + + P L YI+FM R D+ ++ ++ + L+ I ++K+ ++KR + E + LSN ++ +QYSG + F NT+ +H ++DL E+ ++L +L + ++Q +++ +++N+L Q + + +L HE I + + G + +++ + + + + L S ++ H + +I Q+ + Y+I A LN LL R D+C +SKG+QI+YN+S E W+R + L++SGA + L P+ +A QLLQ +D+DA+ +C MC L T Q+VK+LN + P + + R+S I I+ +++ R D P +L P+ PF + ++L IP L L ++
Sbjct: 1 MAASELYTKFARVWIPDPEEVWKSAELLKDYKPGDKVLLLHLEEGKDLEYHLDPKTKELPHLRNPDILVGENDLTALSYLHEPAVLHNLRVRFIDSKLIYTYCGIVLVAINPYEQLPIYGEDIINAYSGQNMGDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYFATVSGSA-------SEANVEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRIIGANMRTYLLEKSRVVFQAEEERNYHIFYQLCASAKLPEFKMLRLG---NADNFNYTKQGGSPVIEGVDDAKEMAHTRQACTLLGISESHQMGIFRILAGILHLGNVGFTSRDADSCTIPPKHEPLCIFCELMGVDYEEMCHWLCHRKLATATETYIKPISKLQATNARDALAKHIYAKLFNWIVDNVNQALHSAVK-----------------QHSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKEQIPWTLIDFYDNQPCINLIESKLGILDLLDEECKMPKGTDDTWAQKLYNTHLNKCALFEKPRLSNKAFIIQHFADKVEYQCEGFLEKNKDTVFEEQIKVLKSSKFKMLPELFQDDEKAISPTSATSSGRTPLTRTPAKPTKGRPGQMAKEHKKTVGHQFRNSLHLLMETLNATTPHYVRCIKPNDFKFPFTFDEKRAVQQLRACGVLETIRISAAGFPSRWTYQEFFSRYRVLMKQKDVLS-DRKQTCKNVLEKLILDKDKYQFGKTKIFFRAGQVAYLEKLRADKLRAACIRIQKTIRGWLLRKKYLRMRKAAITMQRYVRGYQARCYAKFLRRTKAATIIQKYWRMYVVRRRYKIRRAATIVLQSYLRGFLARNRYRKILREHKAVIIQKRVRGWLARTHYKRSMHAIIYLQCCFRRMMAKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNLEGIYNSETEKLRSDLERLQLSEEEAKVATGRVLSLQEEIAKLRKDLEQTRSEKKCIEEHADR------YKQETEQLVSNLKEENTLLKQEKEALNHRIVQQAKEMTETMEKKLVEETKQLELDLNDERLRYQNLLNEFSRLEERYDDL-KEEMTLMVHVPKPGHKRTDSTHSSNESEYIFSSEIAEMEDIPSRTEEPSEKK---------------------VPLDMSLFLKLQKRVTELEQEKQVMQDELDRKEEQVLR-SKAKEEERPQIRGAELEYESL------KRQELESENKKLKNELNELRKALSEKSAPEVTAPGAPAYRVLMEQLTSVSEELDVRKEEVLILRSQLVSQKEAIQPKDDKNTMTDSTILLEDVQKMK-DKGEIAQAYIGLKETNRLLESQLQSQKRSHENEAEALRGEIQSLKEENNRQQQLLAQNLQLPPEARIEASLQHEITRLTNENLDLMEQLEKQDKTVRKLKKQLKVFAKKIGELEVGQMENISPGQIIDEPIRPVNIPRKEKDFQ--------GMLEYKKEDEQKLVKNLILELKPRGVAVNLIP-GLPAYILFMCVRHADYLNDDQKVRSLLTSTINSIKKVLKKRGDDFETVSFWLSNTCRFLHCLKQYSGEEGFMKHNTSRQNEHCLTNFDLAEYRQVLSDLAIQIYQQLVR-VLENIL-QPMIVSGMLEHETIQGVSGVKPTGLRKRTSSIADEGTYTLDSILRQLNSFHSVMCQHGMDPELIKQVVKQMFYIIGAITLNNLLLRKDMCSWSKGMQIRYNVSQLEEWLRDKNLMNSGAKETLEPLIQAAQLLQVKKKTDDDAEAICSMCNALTTAQIVKVLNLYTPVNEFEERVSVSFIRTIQMRLR-DRKDSP---QLLMDAKHIFPVTFPFNPSSLALETIQIPASLGLGFIS 1826
BLAST of Dach-2 vs. Ensembl Human
Match: MYO5A (myosin VA [Source:HGNC Symbol;Acc:HGNC:7602]) HSP 1 Score: 1105.12 bits (2857), Expect = 0.000e+0 Identity = 716/1905 (37.59%), Postives = 1087/1905 (57.06%), Query Frame = 2
Query: 47 MALYEMYSKGVKIWIPDEESVWIGATVLQFHKEKN-VIKIITDNGISKELNLSSK-KCAPFLRNPDILIGQKDLTYLSYLNEPEVLYNLQIRFCERREIYTYCGIVLVAINPYQELSIYGKEIINAYHSQNSVDLDPHIFAVAENAFRRMSSFGENQSIIVSGESGAGKTVSAKYTMRYFALVGGSKTKQSFNLTETQIERKVLLSNPILEAFGNAKTIRNDNSSRFGKYLEILFNPRNQVIGANMCTYLLEKSRVVFQNLGERNYHIFYQIVTHCQSEDELLMNTGLVNNVEMYDYLRYGESLEIDGVDDSHEFLITKNSFLQLGIDLNKFKTICEILAAILHLGNIRFRFHDATDSSIIENPELLKLIAGLLGCSIDQLKIWLCFRTISTFQETLHKPLSKAEAQYFRDAFVKTLYSNLFDWIVKQANKVLSTDVSINIKKKLKKTIVVNQEDKKKFIAVLDIYGFETFAENSFEQFCINFANEKLQLQFNLHVFKLEQEEYMNEGLEWTFIDYYNNQPCIDLIESRXXXXXXXXXXXXXXXXSDENWCCKIYSHHLNKSANFNKPKLSNMVFIIEHFAGPVEYKCAGFIEKNRDSVLEEQINLLKASDVQLIAELFRDSEIEIFDTNNXXXXXXXXXXXXXXXXXXQEN--TRKMKKTVGSQFRNSLKSLMDALNKTNPHYVRCIKPNDLKLPFTFCPERAVQQLRACGVLETIRLSAAGFPSRWTYSDFYHRYYILMSNFNVKNHDFKAGSQKIVETLITVPDAFRFGNTKLFFRPGQVALLEKLRGHKIESSVTLIQSILRGSIERKKYLIIHKLTVQIQTYIRRKLAIEKATKLSQIRAVIIIQSFYRMYLARKLFVKMKCAVLAIEKWRRKIITTRLKQAYKKENCVIICQAIVRRFIQRRKFLKIQRGVILIQNHYRRRKAKETLKILKIEARSINHIKFVNKGLENKIIELTQKLDTKEKEM-CXXXXXX--------XXXXXXXXXXXXXXXAESAKIYQNTVQDLQTEIIQLKKELNREIVEKNKI--FADKELLEINYKKKINYL-ENLIEE---LKSSPSVIEPNIICNGDEAQQSICQD--EHQKFI-----NEQMDHQKLVREYEKLEMKYENLYKEFLFVKSSNQKPSINYDNQTSNDSETESTFSKDDADVESLSDKVDAKTTKEHXXXXXXXXXXLPNFISESISTAGDLAVVMQLQMNISSLSQENNRLKETVQQFEDELLKYEQCAEDSKGLVIHNEYDNELLSIIKDIKGMDEHGLKSRLIDEVANLKKKL-KQSNEDYQKLRLHIFDGSMSKLTGNLDHESINSEEEELKRA-FESQKEANRK------------MLKEIEGIKANNVDLKKALFQIRKDKEQLQVQLGKQHLMIRHGVEYL----QNLK---------------LTPKERLDKFVQNEISRILLENLKLQERNDQIISETIELKRGLKYFAFRLQKYEGSLVPNPNKEEDLLQLIQNVIYHSKMKTIGKRECYSEIGLIDLNMSELSIFIKSFIFDLSP-SICLQYEPYHLVPYIIFMVTRKFDFYKEEDQMTNFLSKLIVALKRTIRKRRNYIEYLVMLLSNVFCLVNLXXXXXXXXXXXXLNTAEDIQHYFVHYDLNEFIRLLKELCVTLFQMILKTIVDNLLPQSLCIDAILVHEAI--IDFLSKDGTKYKSNIETQPKNTSFNVLTKNLQSVLEILKNHKIPQLIINQIFVHIAYLINAYCLNTLLFRTDLCYFSKGLQIKYNLSSFETWIRYQKLIDSGALQCLRPMTEAVQLLQTLIDSDEDAKFVCDMCEYLNTRQVVKILNNFNPRDGYGCRLSSGLIAKIETQMKIKRGDEPSESKLETPTVIEIPIDIPFIHNGVSLCRTIIPKPLYLSCLT 5575
MA E+Y+K ++WIPD E VW A +L+ +K + V+ + + G E +L K K P LRNPDIL+G+ DLT LSYL+EP VL+NL++RF + + IYTYCGIVLVAINPY++L IYG++IINAY QN D+DPHIFAVAE A+++M+ NQSIIVSGESGAGKTVSAKY MRYFA V GS +E +E KVL SNPI+E+ GNAKT RNDNSSRFGKY+EI F+ R ++IGANM TYLLEKSRVVFQ ERNYHIFYQ+ + + ++ G N + ++Y + G S I+GVDD+ E T+ + LGI + I ILA ILHLGN+ F DA +I E L + L+G +++ WLC R ++T ET KP+SK +A RDA K +Y+ LF+WIV N+ L + V + FI VLDIYGFETF NSFEQFCIN+ANEKLQ QFN+HVFKLEQEEYM E + WT ID+Y+NQPCI+LIES+LG+LDLLDEECK+ KG+D+ W K+Y+ HLNK A F KP+LSN FII+HFA VEY+C GF+EKN+D+V EEQI +LK+S +++ ELF+D E I T+ + + + T + + + ++ KKTVG QFRNSL LM+ LN T PHYVRCIKPND K PFTF +RAVQQLRACGVLETIR+SAAGFPSRWTY +F+ RY +LM +V + D K + ++E LI D ++FG TK+FFR GQVA LEKLR K+ ++ IQ +RG + RKKYL + K + +Q Y+R A A L + +A IIQ ++RMY+ R+ + + A + ++ + R + + +E+ +I Q VR ++ R + + +I +Q +RR AK LK LKIEARS+ K ++ G+ENKI++L +K+D + K+ CL++ EK L E AK+ V LQ EI +L+K+L + EK I AD+ YK++ L NL EE LK + I+ E +++ + E K + +E++ +Q L+ E+ +LE +Y++L KE + + KP + T + +E+E FS + A++E + + + + K+ D+++ ++LQ ++ L QE +++ + + E+++L+ + E+ + + E + E L K + +L +E+ L+K L ++S + + M +LT + + EE + R+ SQKEA + +L++++ +K + ++ +A +++ L+ QL Q + E L Q+LK L P+ R++ +Q+EI+R+ ENL L E+ ++ +LK+ LK FA ++ + E + N + + + + I+ V K K G+++ + +K+ I P + + P L YI+FM R D+ ++ ++ + L+ I ++K+ ++KR + E + LSN ++ +QYSG + F NT+ +H ++DL E+ ++L +L + ++Q +++ +++N+L Q + + +L HE I + + G + +++ + + + + L S ++ H + +I Q+ + Y+I A LN LL R D+C +SKG+QI+YN+S E W+R + L++SGA + L P+ +A QLLQ +D+DA+ +C MC L T Q+VK+LN + P + + R+S I I+ +++ R D P +L P+ PF + ++L IP L L ++
Sbjct: 1 MAASELYTKFARVWIPDPEEVWKSAELLKDYKPGDKVLLLHLEEGKDLEYHLDPKTKELPHLRNPDILVGENDLTALSYLHEPAVLHNLRVRFIDSKLIYTYCGIVLVAINPYEQLPIYGEDIINAYSGQNMGDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYFATVSGSA-------SEANVEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRIIGANMRTYLLEKSRVVFQAEEERNYHIFYQLCASAKLPEFKMLRLG---NADNFNYTKQGGSPVIEGVDDAKEMAHTRQACTLLGISESHQMGIFRILAGILHLGNVGFTSRDADSCTIPPKHEPLCIFCELMGVDYEEMCHWLCHRKLATATETYIKPISKLQATNARDALAKHIYAKLFNWIVDNVNQALHSAVK-----------------QHSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKEQIPWTLIDFYDNQPCINLIESKLGILDLLDEECKMPKGTDDTWAQKLYNTHLNKCALFEKPRLSNKAFIIQHFADKVEYQCEGFLEKNKDTVFEEQIKVLKSSKFKMLPELFQDDEKAISPTSATSSGRTPLTRTPAKPTKGRPGQMAKEHKKTVGHQFRNSLHLLMETLNATTPHYVRCIKPNDFKFPFTFDEKRAVQQLRACGVLETIRISAAGFPSRWTYQEFFSRYRVLMKQKDVLS-DRKQTCKNVLEKLILDKDKYQFGKTKIFFRAGQVAYLEKLRADKLRAACIRIQKTIRGWLLRKKYLRMRKAAITMQRYVRGYQARCYAKFLRRTKAATIIQKYWRMYVVRRRYKIRRAATIVLQSYLRGFLARNRYRKILREHKAVIIQKRVRGWLARTHYKRSMHAIIYLQCCFRRMMAKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNLEGIYNSETEKLRSDLERLQLSEEEAKVATGRVLSLQEEIAKLRKDLEQTRSEKKCIEEHADR------YKQETEQLVSNLKEENTLLKQEKEALNHRIVQQAKEMTETMEKKLVEETKQLELDLNDERLRYQNLLNEFSRLEERYDDL-KEEMTLMVHVPKPGHKRTDSTHSSNESEYIFSSEIAEMEDIPSRTEEPSEKK---------------------VPLDMSLFLKLQKRVTELEQEKQVMQDELDRKEEQVLR-SKAKEEERPQIRGAELEYESL------KRQELESENKKLKNELNELRKALSEKSAPEVTAPGAPAYRVLMEQLTSVSEELDVRKEEVLILRSQLVSQKEAIQPKDDKNTMTDSTILLEDVQKMK-DKGEIAQAYIGLKETNRLLESQLQSQKRSHENEAEALRGEIQSLKEENNRQQQLLAQNLQLPPEARIEASLQHEITRLTNENLDLMEQLEKQDKTVRKLKKQLKVFAKKIGELEVGQMENISPGQIIDEPIRPVNIPRKEKDFQ--------GMLEYKKEDEQKLVKNLILGNKPRGVAVNLIP-GLPAYILFMCVRHADYLNDDQKVRSLLTSTINSIKKVLKKRGDDFETVSFWLSNTCRFLHCLKQYSGEEGFMKHNTSRQNEHCLTNFDLAEYRQVLSDLAIQIYQQLVR-VLENIL-QPMIVSGMLEHETIQGVSGVKPTGLRKRTSSIADEGTYTLDSILRQLNSFHSVMCQHGMDPELIKQVVKQMFYIIGAITLNNLLLRKDMCSWSKGMQIRYNVSQLEEWLRDKNLMNSGAKETLEPLIQAAQLLQVKKKTDDDAEAICSMCNALTTAQIVKVLNLYTPVNEFEERVSVSFIRTIQMRLR-DRKDSP---QLLMDAKHIFPVTFPFNPSSLALETIQIPASLGLGFIS 1826
BLAST of Dach-2 vs. Ensembl Human
Match: MYO5A (myosin VA [Source:HGNC Symbol;Acc:HGNC:7602]) HSP 1 Score: 1097.03 bits (2836), Expect = 0.000e+0 Identity = 717/1933 (37.09%), Postives = 1090/1933 (56.39%), Query Frame = 2
Query: 47 MALYEMYSKGVKIWIPDEESVWIGATVLQFHKEKN-VIKIITDNGISKELNLSSK-KCAPFLRNPDILIGQKDLTYLSYLNEPEVLYNLQIRFCERREIYTYCGIVLVAINPYQELSIYGKEIINAYHSQNSVDLDPHIFAVAENAFRRMSSFGENQSIIVSGESGAGKTVSAKYTMRYFALVGGSKTKQSFNLTETQIERKVLLSNPILEAFGNAKTIRNDNSSRFGKYLEILFNPRNQVIGANMCTYLLEKSRVVFQNLGERNYHIFYQIVTHCQSEDELLMNTGLVNNVEMYDYLRYGESLEIDGVDDSHEFLITKNSFLQLGIDLNKFKTICEILAAILHLGNIRFRFHDATDSSIIENPELLKLIAGLLGCSIDQLKIWLCFRTISTFQETLHKPLSKAEAQYFRDAFVKTLYSNLFDWIVKQANKVLSTDVSINIKKKLKKTIVVNQEDKKKFIAVLDIYGFETFAENSFEQFCINFANEKLQLQFNLHVFKLEQEEYMNEGLEWTFIDYYNNQPCIDLIESRXXXXXXXXXXXXXXXXSDENWCCKIYSHHLNKSANFNKPKLSNMVFIIEHFAGPVEYKCAGFIEKNRDSVLEEQINLLKASDVQLIAELFRDSEIEIFDTNNXXXXXXXXXXXXXXXXXXQEN--TRKMKKTVGSQFRNSLKSLMDALNKTNPHYVRCIKPNDLKLPFTFCPERAVQQLRACGVLETIRLSAAGFPSRWTYSDFYHRYYILMSNFNVKNHDFKAGSQKIVETLITVPDAFRFGNTKLFFRPGQVALLEKLRGHKIESSVTLIQSILRGSIERKKYLIIHKLTVQIQTYIRRKLAIEKATKLSQIRAVIIIQSFYRMYLARKLFVKMKCAVLAIEKWRRKIITTRLKQAYKKENCVIICQAIVRRFIQRRKFLKIQRGVILIQNHYRRRKAKETLKILKIEARSINHIKFVNKGLENKIIELTQKLDTKEKEM-CXXXXXX--------XXXXXXXXXXXXXXXAESAKIYQNTVQDLQTEIIQLKKELNREIVEKNKI--FADKELLEINYKKKINYL-ENLIEE---LKSSPSVIEPNIICNGDEAQQSICQD--EHQKFI-----NEQMDHQKLVREYEKLEMKYENLYKEFLFVKSSNQKPSINYDNQTSNDSETESTFSKDDADVESLSDKVDAKTTKEHXXXXXXXXXXLPNFISESISTAGDLAVVMQLQMNISSLSQENNRLKETVQQFEDELLKYEQCAEDSKGLVIHNEYDNELLSIIKDIKGMDEHGLKSRLIDEVANLKKKL-KQSNEDYQKLRLHIFDGSMSKLTGNLDHESINSEEEELKRA-FESQKEANRK------------MLKEIEGIKANNVDLKKALFQIRKDKEQLQVQLGKQHLMIRHGVEYL----QNLK---------------LTPKERLDKFVQNEISRILLENLKLQ----------------------------ERNDQIISETIELKRGLKYFAFRLQKYEGSLVPNPNKEEDLLQLIQNVIYHSKMKTIGKRECYSEIGLIDLNMSELSIFIKSFIFDLSP-SICLQYEPYHLVPYIIFMVTRKFDFYKEEDQMTNFLSKLIVALKRTIRKRRNYIEYLVMLLSNVFCLVNLXXXXXXXXXXXXLNTAEDIQHYFVHYDLNEFIRLLKELCVTLFQMILKTIVDNLLPQSLCIDAILVHEAI--IDFLSKDGTKYKSNIETQPKNTSFNVLTKNLQSVLEILKNHKIPQLIINQIFVHIAYLINAYCLNTLLFRTDLCYFSKGLQIKYNLSSFETWIRYQKLIDSGALQCLRPMTEAVQLLQTLIDSDEDAKFVCDMCEYLNTRQVVKILNNFNPRDGYGCRLSSGLIAKIETQMKIKRGDEPSESKLETPTVIEIPIDIPFIHNGVSLCRTIIPKPLYLSCLT 5575
MA E+Y+K ++WIPD E VW A +L+ +K + V+ + + G E +L K K P LRNPDIL+G+ DLT LSYL+EP VL+NL++RF + + IYTYCGIVLVAINPY++L IYG++IINAY QN D+DPHIFAVAE A+++M+ NQSIIVSGESGAGKTVSAKY MRYFA V GS +E +E KVL SNPI+E+ GNAKT RNDNSSRFGKY+EI F+ R ++IGANM TYLLEKSRVVFQ ERNYHIFYQ+ + + ++ G N + ++Y + G S I+GVDD+ E T+ + LGI + I ILA ILHLGN+ F DA +I E L + L+G +++ WLC R ++T ET KP+SK +A RDA K +Y+ LF+WIV N+ L + V + FI VLDIYGFETF NSFEQFCIN+ANEKLQ QFN+HVFKLEQEEYM E + WT ID+Y+NQPCI+LIES+LG+LDLLDEECK+ KG+D+ W K+Y+ HLNK A F KP+LSN FII+HFA VEY+C GF+EKN+D+V EEQI +LK+S +++ ELF+D E I T+ + + + T + + + ++ KKTVG QFRNSL LM+ LN T PHYVRCIKPND K PFTF +RAVQQLRACGVLETIR+SAAGFPSRWTY +F+ RY +LM +V + D K + ++E LI D ++FG TK+FFR GQVA LEKLR K+ ++ IQ +RG + RKKYL + K + +Q Y+R A A L + +A IIQ ++RMY+ R+ + + A + ++ + R + + +E+ +I Q VR ++ R + + +I +Q +RR AK LK LKIEARS+ K ++ G+ENKI++L +K+D + K+ CL++ EK L E AK+ V LQ EI +L+K+L + EK I AD+ YK++ L NL EE LK + I+ E +++ + E K + +E++ +Q L+ E+ +LE +Y++L KE + + KP + T + +E+E FS + A++E + + + + K+ D+++ ++LQ ++ L QE +++ + + E+++L+ + E+ + + E + E L K + +L +E+ L+K L ++S + + M +LT + + EE + R+ SQKEA + +L++++ +K + ++ +A +++ L+ QL Q + E L Q+LK L P+ R++ +Q+EI+R+ ENL + E+ D+ + +LK+ LK FA ++ + E + N + + + + I+ V K K G+++ + +K+ I +L P + + P L YI+FM R D+ ++ ++ + L+ I ++K+ ++KR + E + LSN ++ +QYSG + F NT+ +H ++DL E+ ++L +L + ++Q +++ +++N+L Q + + +L HE I + + G + +++ + + + + L S ++ H + +I Q+ + Y+I A LN LL R D+C +SKG+QI+YN+S E W+R + L++SGA + L P+ +A QLLQ +D+DA+ +C MC L T Q+VK+LN + P + + R+S I I+ +++ R D P +L P+ PF + ++L IP L L ++
Sbjct: 1 MAASELYTKFARVWIPDPEEVWKSAELLKDYKPGDKVLLLHLEEGKDLEYHLDPKTKELPHLRNPDILVGENDLTALSYLHEPAVLHNLRVRFIDSKLIYTYCGIVLVAINPYEQLPIYGEDIINAYSGQNMGDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYFATVSGSA-------SEANVEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRIIGANMRTYLLEKSRVVFQAEEERNYHIFYQLCASAKLPEFKMLRLG---NADNFNYTKQGGSPVIEGVDDAKEMAHTRQACTLLGISESHQMGIFRILAGILHLGNVGFTSRDADSCTIPPKHEPLCIFCELMGVDYEEMCHWLCHRKLATATETYIKPISKLQATNARDALAKHIYAKLFNWIVDNVNQALHSAVK-----------------QHSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKEQIPWTLIDFYDNQPCINLIESKLGILDLLDEECKMPKGTDDTWAQKLYNTHLNKCALFEKPRLSNKAFIIQHFADKVEYQCEGFLEKNKDTVFEEQIKVLKSSKFKMLPELFQDDEKAISPTSATSSGRTPLTRTPAKPTKGRPGQMAKEHKKTVGHQFRNSLHLLMETLNATTPHYVRCIKPNDFKFPFTFDEKRAVQQLRACGVLETIRISAAGFPSRWTYQEFFSRYRVLMKQKDVLS-DRKQTCKNVLEKLILDKDKYQFGKTKIFFRAGQVAYLEKLRADKLRAACIRIQKTIRGWLLRKKYLRMRKAAITMQRYVRGYQARCYAKFLRRTKAATIIQKYWRMYVVRRRYKIRRAATIVLQSYLRGFLARNRYRKILREHKAVIIQKRVRGWLARTHYKRSMHAIIYLQCCFRRMMAKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNLEGIYNSETEKLRSDLERLQLSEEEAKVATGRVLSLQEEIAKLRKDLEQTRSEKKCIEEHADR------YKQETEQLVSNLKEENTLLKQEKEALNHRIVQQAKEMTETMEKKLVEETKQLELDLNDERLRYQNLLNEFSRLEERYDDL-KEEMTLMVHVPKPGHKRTDSTHSSNESEYIFSSEIAEMEDIPSRTEEPSEKK---------------------VPLDMSLFLKLQKRVTELEQEKQVMQDELDRKEEQVLR-SKAKEEERPQIRGAELEYESL------KRQELESENKKLKNELNELRKALSEKSAPEVTAPGAPAYRVLMEQLTSVSEELDVRKEEVLILRSQLVSQKEAIQPKDDKNTMTDSTILLEDVQKMK-DKGEIAQAYIGLKETNRLLESQLQSQKRSHENEAEALRGEIQSLKEENNRQQQLLAQNLQLPPEARIEASLQHEITRLTNENLYFEELYADDPKKYQSYRISLYKRMIDLMEQLEKQDKTVR---KLKKQLKVFAKKIGELEVGQMENISPGQIIDEPIRPVNIPRKEKDFQ--------GMLEYKKEDEQKLVKNLILELKPRGVAVNLIP-GLPAYILFMCVRHADYLNDDQKVRSLLTSTINSIKKVLKKRGDDFETVSFWLSNTCRFLHCLKQYSGEEGFMKHNTSRQNEHCLTNFDLAEYRQVLSDLAIQIYQQLVR-VLENIL-QPMIVSGMLEHETIQGVSGVKPTGLRKRTSSIADEGTYTLDSILRQLNSFHSVMCQHGMDPELIKQVVKQMFYIIGAITLNNLLLRKDMCSWSKGMQIRYNVSQLEEWLRDKNLMNSGAKETLEPLIQAAQLLQVKKKTDDDAEAICSMCNALTTAQIVKVLNLYTPVNEFEERVSVSFIRTIQMRLR-DRKDSP---QLLMDAKHIFPVTFPFNPSSLALETIQIPASLGLGFIS 1851
BLAST of Dach-2 vs. Ensembl Human
Match: MYO5A (myosin VA [Source:HGNC Symbol;Acc:HGNC:7602]) HSP 1 Score: 1095.49 bits (2832), Expect = 0.000e+0 Identity = 722/1919 (37.62%), Postives = 1093/1919 (56.96%), Query Frame = 2
Query: 47 MALYEMYSKGVKIWIPDEESVWIGATVLQFHKEKN-VIKIITDNGISKELNLSSK-KCAPFLRNPDILIGQKDLTYLSYLNEPEVLYNLQIRFCERREIYTYCGIVLVAINPYQELSIYGKEIINAYHSQNSVDLDPHIFAVAENAFRRMSSFGENQSIIVSGESGAGKTVSAKYTMRYFALVGGSKTKQSFNLTETQIERKVLLSNPILEAFGNAKTIRNDNSSRFGKYLEILFNPRNQVIGANMCTYLLEKSRVVFQNLGERNYHIFYQIVTHCQSEDELLMNTGLVNNVEMYDYLRYGESLEIDGVDDSHEFLITKNSFLQLGIDLNKFKTICEILAAILHLGNIRFRFHDATDSSIIENPELLKLIAGLLGCSIDQLKIWLCFRTISTFQETLHKPLSKAEAQYFRDAFVKTLYSNLFDWIVKQANKVLSTDVSINIKKKLKKTIVVNQEDKKKFIAVLDIYGFETFAENSFEQFCINFANEKLQLQFNLHVFKLEQEEYMNEGLEWTFIDYYNNQPCIDLIESRXXXXXXXXXXXXXXXXSDENWCCKIYSHHLNKSANFNKPKLSNMVFIIEHFAGPVEYKCAGFIEKNRDSVLEEQINLLKASDVQLIAELFRDSEIEIFDTNNXXXXXXXXXXXXXXXXXXQEN--TRKMKKTVGSQFRNSLKSLMDALNKTNPHYVRCIKPNDLKLPFTFCPERAVQQLRACGVLETIRLSAAGFPSRWTYSDFYHRYYILMSNFNVKNHDFKAGSQKIVETLITVPDAFRFGNTKLFFRPGQVALLEKLRGHKIESSVTLIQSILRGSIERKKYLIIHKLTVQIQTYIRRKLAIEKATKLSQIRAVIIIQSFYRMYLARKLFVKMKCAVLAIEKWRRKIITTRLKQAYKKENCVIICQAIVRRFIQRRKFLKIQRGVILIQNHYRRRKAKETLKILKIEARSINHIKFVNKGLENKIIELTQKLDTKEKEM-CXXXXXX--------XXXXXXXXXXXXXXXAESAKIYQNTVQDLQTEIIQLKKELNREIVEKNKI--FADKELLEINYKKKINYL-ENLIEE---LKSSPSVIEPNIICNGDEAQQSICQD--EHQKFI-----NEQMDHQKLVREYEKLEMKYENLYKEFLFVKSSNQKPSINYDNQTSNDSETESTFSKDDADVESLSDKVDAKTTKEHXXXXXXXXXXLPNFISESISTAGDLAVVMQLQMN------ISSLSQENNRLKETVQQFEDELLKYEQCAEDSK------------------------GLVIHNEYDNELLSIIK--DIKGMDEHGLKSRLIDEVANLKKKLKQSN--------EDYQKLR-----LHIFDG-SMSKLTGNLDHESINSEEEELKRAFESQKEANRKMLKEIEGIKANNVDLKKAL-FQIRKDKEQLQVQLGKQHLMIRHGVEYLQNLKLTPKERLDKFVQNEISRILLENLKLQERNDQIISETIELKRGLKYFAFRLQKYEGSLVPNPNKEEDLLQLIQNVIYHSKMKTIGKRECYSEIGLIDLNMSELSIFIKSFIFDLSP-SICLQYEPYHLVPYIIFMVTRKFDFYKEEDQMTNFLSKLIVALKRTIRKRRNYIEYLVMLLSNVFCLVNLXXXXXXXXXXXXLNTAEDIQHYFVHYDLNEFIRLLKELCVTLFQMILKTIVDNLLPQSLCIDAILVHEAI--IDFLSKDGTKYKSNIETQPKNTSFNVLTKNLQSVLEILKNHKIPQLIINQIFVHIAYLINAYCLNTLLFRTDLCYFSKGLQIKYNLSSFETWIRYQKLIDSGALQCLRPMTEAVQLLQTLIDSDEDAKFVCDMCEYLNTRQVVKILNNFNPRDGYGCRLSSGLIAKIETQMKIKRGDEPSESKLETPTVIEIPIDIPFIHNGVSLCRTIIPKPLYLSCLT 5575
MA E+Y+K ++WIPD E VW A +L+ +K + V+ + + G E +L K K P LRNPDIL+G+ DLT LSYL+EP VL+NL++RF + + IYTYCGIVLVAINPY++L IYG++IINAY QN D+DPHIFAVAE A+++M+ NQSIIVSGESGAGKTVSAKY MRYFA V GS + E +E KVL SNPI+E+ GNAKT RNDNSSRFGKY+EI F+ R ++IGANM TYLLEKSRVVFQ ERNYHIFYQ+ + + ++ G N + ++Y + G S I+GVDD+ E T+ + LGI + I ILA ILHLGN+ F DA +I E L + L+G +++ WLC R ++T ET KP+SK +A RDA K +Y+ LF+WIV N+ L + V + FI VLDIYGFETF NSFEQFCIN+ANEKLQ QFN+HVFKLEQEEYM E + WT ID+Y+NQPCI+LIES+LG+LDLLDEECK+ KG+D+ W K+Y+ HLNK A F KP+LSN FII+HFA VEY+C GF+EKN+D+V EEQI +LK+S +++ ELF+D E I T+ + + + T + + + ++ KKTVG QFRNSL LM+ LN T PHYVRCIKPND K PFTF +RAVQQLRACGVLETIR+SAAGFPSRWTY +F+ RY +LM +V + D K + ++E LI D ++FG TK+FFR GQVA LEKLR K+ ++ IQ +RG + RKKYL + K + +Q Y+R A A L + +A IIQ ++RMY+ R+ + + A + ++ + R + + +E+ +I Q VR ++ R + + +I +Q +RR AK LK LKIEARS+ K ++ G+ENKI++L +K+D + K+ CL++ EK L E AK+ V LQ EI +L+K+L + EK I AD+ YK++ L NL EE LK + I+ E +++ + E K + +E++ +Q L+ E+ +LE +Y++L KE + + KP + T + +E+E FS + A++E + + T+E K + L + + ++ VMQ +++ + S ++E R + + E E LK ++ ++K G + +L S+ + D++ + L+S+L+ + ++ K ++ ED QK++ + G + + LD+ +N E+ EL +E K+ANR + +++ K ++ + +AL +I+ KE+ R QNL+L P+ R++ +Q+EI+R+ ENL L E+ ++ +LK+ LK FA ++ + E + N + + + + I+ V K K G+++ + +K+ I P + + P L YI+FM R D+ ++ ++ + L+ I ++K+ ++KR + E + LSN ++ +QYSG + F NT+ +H ++DL E+ ++L +L + ++Q +++ +++N+L Q + + +L HE I + + G + +++ + + + + L S ++ H + +I Q+ + Y+I A LN LL R D+C +SKG+QI+YN+S E W+R + L++SGA + L P+ +A QLLQ +D+DA+ +C MC L T Q+VK+LN + P + + R+S I I+ +++ R D P +L P+ PF + ++L IP L L ++
Sbjct: 1 MAASELYTKFARVWIPDPEEVWKSAELLKDYKPGDKVLLLHLEEGKDLEYHLDPKTKELPHLRNPDILVGENDLTALSYLHEPAVLHNLRVRFIDSKLIYTYCGIVLVAINPYEQLPIYGEDIINAYSGQNMGDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYFATVSGSAS-------EANVEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRIIGANMRTYLLEKSRVVFQAEEERNYHIFYQLCASAKLPEFKMLRLG---NADNFNYTKQGGSPVIEGVDDAKEMAHTRQACTLLGISESHQMGIFRILAGILHLGNVGFTSRDADSCTIPPKHEPLCIFCELMGVDYEEMCHWLCHRKLATATETYIKPISKLQATNARDALAKHIYAKLFNWIVDNVNQALHSAVK-----------------QHSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKEQIPWTLIDFYDNQPCINLIESKLGILDLLDEECKMPKGTDDTWAQKLYNTHLNKCALFEKPRLSNKAFIIQHFADKVEYQCEGFLEKNKDTVFEEQIKVLKSSKFKMLPELFQDDEKAISPTSATSSGRTPLTRTPAKPTKGRPGQMAKEHKKTVGHQFRNSLHLLMETLNATTPHYVRCIKPNDFKFPFTFDEKRAVQQLRACGVLETIRISAAGFPSRWTYQEFFSRYRVLMKQKDVLS-DRKQTCKNVLEKLILDKDKYQFGKTKIFFRAGQVAYLEKLRADKLRAACIRIQKTIRGWLLRKKYLRMRKAAITMQRYVRGYQARCYAKFLRRTKAATIIQKYWRMYVVRRRYKIRRAATIVLQSYLRGFLARNRYRKILREHKAVIIQKRVRGWLARTHYKRSMHAIIYLQCCFRRMMAKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNLEGIYNSETEKLRSDLERLQLSEEEAKVATGRVLSLQEEIAKLRKDLEQTRSEKKCIEEHADR------YKQETEQLVSNLKEENTLLKQEKEALNHRIVQQAKEMTETMEKKLVEETKQLELDLNDERLRYQNLLNEFSRLEERYDDL-KEEMTLMVHVPKPGHKRTDSTHSSNESEYIFSSEIAEMEDIPSR-----TEEPSEKKVPLDMSLFLKLQKRVTELEQEKQVMQDELDRKEEQVLRSKAKEEERPQIRGAELEYESLKRQELESENKKLKNELNELRKALSEKSAPEVTAPGAPAYRVLMEQLTSVSEELDVRKEEVLILRSQLVSQKEAIQPKDDKNTMTDSTILLEDVQKMKDKGEIAQAYIGLKETNRSSALDYHELN-EDGELWLVYEGLKQANRLLESQLQSQKRSHENEAEALRGEIQSLKEENN----------RQQQLLAQNLQLPPEARIEASLQHEITRLTNENLDLMEQLEKQDKTVRKLKKQLKVFAKKIGELEVGQMENISPGQIIDEPIRPVNIPRKEKDFQ--------GMLEYKKEDEQKLVKNLILGNKPRGVAVNLIP-GLPAYILFMCVRHADYLNDDQKVRSLLTSTINSIKKVLKKRGDDFETVSFWLSNTCRFLHCLKQYSGEEGFMKHNTSRQNEHCLTNFDLAEYRQVLSDLAIQIYQQLVR-VLENIL-QPMIVSGMLEHETIQGVSGVKPTGLRKRTSSIADEGTYTLDSILRQLNSFHSVMCQHGMDPELIKQVVKQMFYIIGAITLNNLLLRKDMCSWSKGMQIRYNVSQLEEWLRDKNLMNSGAKETLEPLIQAAQLLQVKKKTDDDAEAICSMCNALTTAQIVKVLNLYTPVNEFEERVSVSFIRTIQMRLR-DRKDSP---QLLMDAKHIFPVTFPFNPSSLALETIQIPASLGLGFIS 1853
BLAST of Dach-2 vs. Ensembl Human
Match: MYO5B (myosin VB [Source:HGNC Symbol;Acc:HGNC:7603]) HSP 1 Score: 1091.26 bits (2821), Expect = 0.000e+0 Identity = 716/1915 (37.39%), Postives = 1064/1915 (55.56%), Query Frame = 2
Query: 47 MALYEMYSKGVKIWIPDEESVWIGATVLQFHKE--KNVIKIITDNGISKELNLSSKKCAPFLRNPDILIGQKDLTYLSYLNEPEVLYNLQIRFCERREIYTYCGIVLVAINPYQELSIYGKEIINAYHSQNSVDLDPHIFAVAENAFRRMSSFGENQSIIVSGESGAGKTVSAKYTMRYFALVGGSKTKQSFNLTETQIERKVLLSNPILEAFGNAKTIRNDNSSRFGKYLEILFNPRNQVIGANMCTYLLEKSRVVFQNLGERNYHIFYQIVTHCQSEDELLMNTGLVNNVEMYDYLRYGESLEIDGVDDSHEFLITKNSFLQLGIDLNKFKTICEILAAILHLGNIRFRFHDATDSSIIENPEL-LKLIAGLLGCSIDQLKIWLCFRTISTFQETLHKPLSKAEAQYFRDAFVKTLYSNLFDWIVKQANKVLSTDVSINIKKKLKKTIVVNQEDKKKFIAVLDIYGFETFAENSFEQFCINFANEKLQLQFNLHVFKLEQEEYMNEGLEWTFIDYYNNQPCIDLIESRXXXXXXXXXXXXXXXXSDENWCCKIYSHHLNKSANFNKPKLSNMVFIIEHFAGPVEYKCAGFIEKNRDSVLEEQINLLKASDVQLIAELFRDSEIEIFDTNNXXXXXXXXXXXXXXXXXXQENTRKMKKTVGSQFRNSLKSLMDALNKTNPHYVRCIKPNDLKLPFTFCPERAVQQLRACGVLETIRLSAAGFPSRWTYSDFYHRYYILMSNFNVKNHDFKAGSQKIVETLITVPDAFRFGNTKLFFRPGQVALLEKLRGHKIESSVTLIQSILRGSIERKKYLIIHKLTVQIQTYIRRKLAIEKATKLSQIRAVIIIQSFYRMYLARKLFVKMKCAVLAIEKWRRKIITTRLKQAYKKENCVIICQAIVRRFIQRRKFLKIQRGVILIQNHYRRRKAKETLKILKIEARSINHIKFVNKGLENKIIELTQKLDTKEKEMCXXXXXXXXXXXXXXXXXXXXXAESAKIYQNTVQD----LQTEIIQLKKELNREIVEKNKIFADKELLEIN-YKKKINYLENLIEELKSSPSVIEPNIICNGDE--AQQSICQDEHQKFINEQMD-HQKLVREYEKLEMKYENLYKEFLFVKSSNQKPSINYDNQTSNDSETESTFSKDDADVESLSDKVDAKTTKEHXXXXXXXXXXLPNFISESISTAGDLAVVMQLQMNISSLSQENNRLKETVQQFEDELLKYEQCAEDSKGLVIHNEYD----------------------NELLSIIKD--IKGMDEHGLK---SRLIDEVANLKKKLKQSNEDYQKLRLHIFDGSMSKLTGNLDHESINS-----------EEEELKRAFESQKEANRKMLKEIEGIKANNVDLKKALFQIRKDKEQLQVQLGKQHL-------------------MIRHGVEYLQNLKLTPKERLDKFVQNEISRILLENLKLQERNDQIISETIELKRGLKYFAFRLQKYEG--SLVPNPNKEEDLLQLIQNVIYHSKMKTIGKRECYSEIGLIDLNMSELSIFIKSFIFDLSPSICLQYEPYHLVPYIIFMVTRKFDFYKEEDQMTNFLSKLIVALKRTIRKRRNYIEYLVMLLSNVFCLVNLXXXXXXXXXXXXLNTAEDIQHYFVHYDLNEFIRLLKELCVTLFQMILKTIVDNLLPQSLCIDAILVHEAIIDFLSKDGTKYK---SNIETQPKNTSFNVLTKNLQSVLEILKNHKIPQLIINQIFVHIAYLINAYCLNTLLFRTDLCYFSKGLQIKYNLSSFETWIRYQKLIDSGALQCLRPMTEAVQLLQTLIDSDEDAKFVCDMCEYLNTRQVVKILNNFNPRDGYGCRLSSGLIAKIETQMKIKRGDEPSESKLETPTVIEIPIDIPFIHNGVSLCRTIIPKPLYLSCL 5572
M++ E+YS+ ++WIPD + VW A + + +KE K++ + D I + + PFLRNPDIL+G+ DLT LSYL+EP VL+NL++RF E IYTYCGIVLVAINPY++L IYG+++I Y QN D+DPHIFAVAE A+++M+ +NQSIIVSGESGAGKTVSAKY MRYFA VGGS + ET IE KVL S+PI+EA GNAKT RNDNSSRFGKY++I F+ R +IGANM TYLLEKSRVVFQ ERNYHIFYQ+ C + + + E + Y G I+GVDD+ +F T+ +F LG+ + +I +I+A+ILHLG++ + DS I ++ L LLG Q++ WLC R + T ET K +S + R+A K +Y+ LF WIV+ NK L T + + FI VLDIYGFETF NSFEQFCIN+ANEKLQ QFN HVFKLEQEEYM E + WT ID+Y+NQPCIDLIE++LG+LDLLDEECK+ KG+D+NW K+Y H + S +F KP++SN FII HFA VEY GF+EKNRD+V EEQIN+LKAS L+A+LF D + + T K S S + +K N ++ KKTVG QFR SL LM+ LN T PHYVRCIKPND KLPF F P+RAVQQLRACGVLETIR+SAAG+PSRW Y DF++RY +L+ + N D KA + ++E LI PD F+FG TK+FFR GQVA LEKLR K ++ +IQ +RG +++ KY + T+ +Q Y R LA A L +IRA +++Q YRM AR+ + +++ A + I+ + R + R + E+ Q VR ++ RR F +++ I+IQ +R KA+ LK L+IEARS H+K +N G+ENK+++L +K+D + KE + QL + ++ + E Q+ +D LQ E+ L+ EL R E+ KI D E + +K++ LE LK + I+C + AQ S+ ++ +K + E+ +Q LV+EY +LE +Y+NL E +K Q P + SN S ES + + D DA E + A D+ V ++LQ + L QE +L+ +++ E + K Q + + D NEL + D + HG S L++++ ++L+ E+ LR I +L G +IN+ ++E+ A+ + N K E G + +L A +++ L+ QL Q L M + + Q L L+P+ +++ VQ EISR+ ENL L+E +++ +LK+ LK + + Q E +L + K +L ++ T+ ++E + G+++ + + ++ I++ + DL P + P L YI++M R D+ ++ ++ + L+ I +K+ ++K + E LSN L++ +QYSG + F NTA+ +H ++DL E+ ++L +L + ++Q ++K I + +L Q + + A+L +E+I T Y+ S++ + + + + + ++ + + II Q+F + Y+INA LN LL R D+C +S G+Q++YN+S E W+R + L SGA+Q + P+ +A QLLQ + EDA+ +C +C L+T+Q+VKILN + P + + R++ I I+ Q++ +R D P + L+ + P+ PF + +++ IP L L L
Sbjct: 1 MSVGELYSQCTRVWIPDPDEVWRSAELTKDYKEGDKSLQLRLEDETILEYPIDVQRNQLPFLRNPDILVGENDLTALSYLHEPAVLHNLKVRFLESNHIYTYCGIVLVAINPYEQLPIYGQDVIYTYSGQNMGDMDPHIFAVAEEAYKQMARDEKNQSIIVSGESGAGKTVSAKYAMRYFATVGGSAS-------ETNIEEKVLASSPIMEAIGNAKTTRNDNSSRFGKYIQIGFDKRYHIIGANMRTYLLEKSRVVFQADDERNYHIFYQL---CAAAGLPEFKELALTSAEDFFYTSQGGDTSIEGVDDAEDFEKTRQAFTLLGVKESHQMSIFKIIASILHLGSVAIQAERDGDSCSISPQDVYLSNFCRLLGVEHSQMEHWLCHRKLVTTSETYVKTMSLQQVINARNALAKHIYAQLFGWIVEHINKALHTSLK-----------------QHSFIGVLDIYGFETFEVNSFEQFCINYANEKLQQQFNSHVFKLEQEEYMKEQIPWTLIDFYDNQPCIDLIEAKLGILDLLDEECKVPKGTDQNWAQKLYDRH-SSSQHFQKPRMSNTAFIIVHFADKVEYLSDGFLEKNRDTVYEEQINILKASKFPLVADLFHDDKDPVPATTPGKGSSSKISVRSARPPMKVSN-KEHKKTVGHQFRTSLHLLMETLNATTPHYVRCIKPNDEKLPFHFDPKRAVQQLRACGVLETIRISAAGYPSRWAYHDFFNRYRVLVKKRELANTDKKAICRSVLENLIKDPDKFQFGRTKIFFRAGQVAYLEKLRADKFRTATIMIQKTVRGWLQKVKYHRLKGATLTLQRYCRGHLARRLAEHLRRIRAAVVLQKHYRMQRARQAYQRVRRAAVVIQAFTRAMFVRRTYRQVLMEHKATTIQKHVRGWMARRHFQRLRDAAIVIQCAFRMLKARRELKALRIEARSAEHLKRLNVGMENKVVQLQRKIDEQNKEFKTLSEQLSVTTSTYTMEVERLKKELVHYQQSPGEDTSLRLQEEVESLRTELQRAHSER-KILEDAHSREKDELRKRVADLEQENALLKDEKEQLNNQILCQSKDEFAQNSVKENLMKKELEEERSRYQNLVKEYSQLEQRYDNLRDEMTIIK---QTPG--HRRNPSNQSSLESDSNYPSISTSEIGDTEDALQQVEEIGLE---------------KAAMDMTVFLKLQKRVRELEQERKKLQVQLEKREQQDSKKVQAEPPQTDIDLDPNADLAYNSLKRQELESENKKLKNDLNELRKAVADQATQNNSSHGSPDSYSLLLNQLKLAHEELEVRKEEVLILRTQIVSADQRRLAGRNAEPNINARSSWPNSEKHVDQEDAIEAYHGVCQTNSKT--EDWGYLNEDGELGLAYQGLKQVARLLEAQLQAQSLEHEEEVEHLKAQLEALKEEMDKQQQTFCQTLLLSPEAQVEFGVQQEISRLTNENLDLKELVEKLEKNERKLKKQLKIYMKKAQDLEAAQALAQSERKRHEL----------NRQVTVQRKEKDFQ-GMLEYHKEDEALLIRNLVTDLKPQMLSGTVPC-LPAYILYMCIRHADYTNDDLKVHSLLTSTINGIKKVLKKHNDDFEMTSFWLSNTCRLLHCLKQYSGDEGFMTQNTAKQNEHCLKNFDLTEYRQVLSDLSIQIYQQLIK-IAEGVL-QPMIVSAMLENESIQGLSGVKPTGYRKRSSSMADGDNSYCLEAIIRQMNAFHTVMCDQGLDPEIILQVFKQLFYMINAVTLNNLLLRKDVCSWSTGMQLRYNISQLEEWLRGRNLHQSGAVQTMEPLIQAAQLLQLKKKTQEDAEAICSLCTSLSTQQIVKILNLYTPLNEFEERVTVAFIRTIQAQLQ-ERND-PQQLLLDAKHM--FPVLFPFNPSSLTMDSIHIPACLNLEFL 1845
BLAST of Dach-2 vs. Ensembl Celegans
Match: hum-2 (Heavy chain, Unconventional Myosin [Source:UniProtKB/TrEMBL;Acc:A0A168H5A5]) HSP 1 Score: 727.243 bits (1876), Expect = 0.000e+0 Identity = 465/1158 (40.16%), Postives = 671/1158 (57.94%), Query Frame = 2
Query: 65 YSKGVKIWIPDEESVWIGATV---LQFHKEKNVIKIITDNGISKELNLSSKKCAPFLRNPDILIGQKDLTYLSYLNEPEVLYNLQIRFCERREIYTYCGIVLVAINPYQELS-IYGKEIINAYHS--QNSVDLDPHIFAVAENAFRRMSSFGENQSIIVSGESGAGKTVSAKYTMRYFALVGGSKTKQSFNLTETQIERKVLLSNPILEAFGNAKTIRNDNSSRFGKYLEILFNPRNQ-VIGANMCTYLLEKSRVVFQNLGERNYHIFYQIVTHCQSEDELLMNTGLVNNVEMYDYLRYGESLEIDGVDDSHEFLITKNSFLQLGIDLNKFKTICEILAAILHLGNIRFRFHDATDS-SIIENPELLKLIAGLLGCSIDQLKIWLCFRTISTFQETLHKPLSKAEAQYFRDAFVKTLYSNLFDWIVKQANKVLSTDVSINIKKKLKKTIVVNQEDKK-KFIAVLDIYGFETFAENSFEQFCINFANEKLQLQFNLHVFKLEQEEYMNEGLEWTFIDYYNNQPCIDLIESRXXXXXXXXXXXXXXXXSDENWCCKIY-SHHLNKSANFNKPKLSNMVFIIEHFAGPVEYKCAGFIEKNRDSVLEEQINLLKASDVQLIAELFRDSEIEIFDTNNXXXXXXXXXXXXXXXXXXQENTRKMKKTVGSQFRNSLKSLMDALNKTNPHYVRCIKPNDLKLPFTFCPERAVQQLRACGVLETIRLSAAGFPSRWTYSDFYHRYYILMSNFNVKNHDFKAGSQKIVETLITVPDAFRFGNTKLFFRPGQVALLEKLRGHKIESSVTLIQSILRGSIERKKYLIIHKLTVQIQTYIRRKLAIEKATKLSQIRAVIIIQSFYRMYLARKLFVKMKCAVLAIEKWRRKIITTRLKQAYKKENCVIICQAIVRRFIQRRKFLKIQRGVILIQNHYRRRKAKETLKILKIEARSINHIKFVNKGLENKIIELTQKLD---TKEKEMCXXXXXXXXXXXXXXXXXXXXXAESAKIYQ--NTVQDLQTEIIQLKKELNREIVEKNKIFADKELLEINYKKKINYLENLIEELKSSPSVIEPNIICNGDEAQQSICQDEHQKFINEQMDHQKLVREYEKLE--------MKYENLYKEFLFVKSSNQKPSINYDN---QTSNDSETESTFSKD 3460
+ KGV+IW VWIGAT+ + F I++ D + E + S PFLRNP L+G+ DLT LSYL+EP VL+NLQ+RF + IYTYCGIVLVAINPY + S IYG+EII Y +++ ++DPHIFAVAE A M +FG++QSIIVSGESGAGKTVSAK+ MRY A V SKT+ N T IE +VL SNPI+E+ GNAKTIRNDNSSRFGK+++I F R + ++GA M TYLLEKSR+VFQ GERNYHIFYQ+ C + + ++ + E Y YL G I GVDD +F + LG D + + +LA +L LGN+ F + + + S E+ +L S L+IWL R I E + KPL+K EA RDA K LYS+LF W+V + N+ L N K KL T NQ+ + +FI VLDIYGFETF NSFEQF IN+ANEKLQ QFN HVFKLEQEEY+ E +EW +D+++NQP IDLIE +G+++LLDE+CK L GSD +W ++ S L ++ PK+ + FI+ HFA V Y GF+EKNRD++ E+ ++++ AS I + + +S S S R +KKTV SQFR+SLK LM L T PHYVRCIKPND K+ F F P+RA+QQLRACGVLET+R+SAAGFPSR+ Y +F RY ++ + D ++ + G TK+F R GQVA+LE++R + ++ T+IQ + +G + R+KY + + + +Q ++ LA + L RAVI++QS R YL R+ + +++ +++ I+ + R + + E I QA R ++ RR+ + ++ V+++Q R+ AK L+ LKIEARS+ H++ +N GLENKIIEL +LD + KE K + +L + +AE + + N V+ LQ E+ +L+ E + + E + + +++E+ + L+ + +S +++E +A + + +E Q+ + ++ ++ R E MK +L++ F K +QK + + D+ TSN S+ +F+ +
Sbjct: 18 FKKGVRIWHRHPTLVWIGATLEEDITFQTRNVRIRLEDDTEV--EYAIKSLDQLPFLRNPAFLVGKDDLTLLSYLHEPAVLHNLQVRFVKGSSIYTYCGIVLVAINPYADCSHIYGEEIIQVYRGAGKSAREMDPHIFAVAEEAHFDMGAFGKSQSIIVSGESGAGKTVSAKFVMRYLASVAASKTR---NGGTTSIEARVLASNPIMESIGNAKTIRNDNSSRFGKFIQINFCERGRRIVGAEMKTYLLEKSRLVFQAPGERNYHIFYQL---CAARNHQVLKDLHLGPCESYSYLTQGGDSRIPGVDDKADFEALLKALQLLGFDEKQMSDVFRLLAGLLLLGNVHFENGEGSSAVSASSCQEISRLCREFWKISESDLRIWLTRREIRAVNEIVTKPLTKNEAVRSRDALTKMLYSHLFGWLVDKINEAL------NEKDKLDGT---NQKKRPDRFIGVLDIYGFETFDVNSFEQFSINYANEKLQQQFNQHVFKLEQEEYIREEIEWVRVDFHDNQPAIDLIEGPVGMINLLDEQCKRLNGSDADWLSQLQNSTELKRNPQLAFPKVRSNDFIVRHFAADVTYSTDGFVEKNRDAIGEQLLDVVVASKFPFIRTVI---------------GSTAPTSVSSSSSSSTPGKRTIKKTVASQFRDSLKELMSVLCSTRPHYVRCIKPNDSKISFDFEPKRAIQQLRACGVLETVRISAAGFPSRYPYEEFARRYRVIYTKEAALWRDKPKQFAELACQQCLEEGKYAVGKTKIFLRTGQVAVLERVRLDTLAAAATVIQKMWKGFLARRKYETMRRSLLIVQASLKAFLAFRRIKYLQMHRAVIVMQSAVRGYLERRKYEQIRDSIIGIQAMFKANRVRRYVEKLRYEKSAITIQAAWRGYLARREQIANRKKVVMVQCAVRKWLAKRRLRELKIEARSVGHLQKLNTGLENKIIELQMRLDIANARTKEEAEKFATASKNLQKTKADLAMMEAERLTLLEARNRVEVLQEEVERLETECD--LKEAQRGGMETKMVELQSR-----LDQFQMQSESGQTIVELTEQLEKAKADRVLWDEERQR-MEAALNTERSARNALDAEMAAMREQLMKNVDLFESSTFQKRPSQKKNRDDDSCSRTTSNLSQLTGSFTAE 1135 HSP 2 Score: 100.523 bits (249), Expect = 1.101e-20 Identity = 112/460 (24.35%), Postives = 205/460 (44.57%), Query Frame = 2
Query: 4235 NDQIISETIELKRGLKYFAFRLQKYEGSLVPNPNKEEDLLQLIQNVIYHSKMKTIGKRECYSEIGLIDLNMSELSIFIKSFIFDLSPSICLQYEPYHLVPYIIFMVTRKFDFYKEEDQMTNFLSKLIVALKRTIRKRRNYIEYLVMLLSNVFCLVNLXXXXXXXXXXXXL---NTAEDIQHYFVHYDLNEFIRLLKELCVTLFQMILKTIVDNLLPQSLCIDAILVHEAIIDFLSKDGTKYKSN---IETQPKNTSFNVLTKNLQSVLEILKNHKIPQLIINQIFVHIAYLINAYCLNTLLFRTDLCYFSKGLQIKYNLSSFETWIRYQKLIDSGALQCLRPMTEAVQLLQTLIDSDEDAKFVCDMCEYLNTRQVVKILNNFNPRDGYGCRLSSGLIAKIETQM--KIKRGDEPSE--SKLETPTVIEIPIDI-PFIHNGVSLCRTIIPKPLYLSCLTVL 5581
ND++ ++ EL +L+ Y G L +E++++L +K G E Y N+ E F + + +L P++ + +L Y++ R D ++E +T S + + LK TI R + ++ L + L N++ L NL +QYSG NT + F YD+ LK + ++K ++++L + + IL HE+ D ++ + N +E+Q K S + L + ++ V L + +++ Q+ +A + A LN ++FR +LC F K +QIK+N++ + W+ + L D P+ +A LLQ+ D +M L RQVV IL +++P D LS + +I+ ++ + ++P E KL P D PF ++ L +P L++ + L
Sbjct: 1375 NDKLTRQSEELAEARA----QLRGYSGPLGLENASDEEIIRL--EAFEKGSIKHSGFLEVY--------NVPE---FARIIVCELKPTLA-RLLTKNLPAYLLVAAFRNHDEKRDETALTGLFSSVHLVLKDTI-SRSHDLDLLSLWLVNLWRLFNLLRQYSGEDSQPEWHVANTETQNSYRFKAYDVAPIRDQLKLRIEECYTSLMKKAIEHVLSPKI-VPGILQHESSSDLMTAGQERRDRNSGSVESQRK--SLDDLLQFMEIVHTKLTTYGGDDIVVKQVIGQMARWMCALALNYMMFRRELCNFEKAIQIKHNVTQIQNWLNAKGLSD--CRDHFEPLVQACHLLQSRKDPSNLDTLCGEMTSRLKPRQVVAILQHYDPSDEMEDGLSPEFLVQIQKKLNERAIANNDPIEDKDKLIMLGTYLPPFDTQPFSYSDFPLETLSLPSCLHMQSVCRL 1810
BLAST of Dach-2 vs. Ensembl Celegans
Match: hum-2 (Heavy chain, Unconventional Myosin [Source:UniProtKB/TrEMBL;Acc:A0A168H5A5]) HSP 1 Score: 725.702 bits (1872), Expect = 0.000e+0 Identity = 464/1158 (40.07%), Postives = 674/1158 (58.20%), Query Frame = 2
Query: 65 YSKGVKIWIPDEESVWIGATV---LQFHKEKNVIKIITDNGISKELNLSSKKCAPFLRNPDILIGQKDLTYLSYLNEPEVLYNLQIRFCERREIYTYCGIVLVAINPYQELS-IYGKEIINAYHS--QNSVDLDPHIFAVAENAFRRMSSFGENQSIIVSGESGAGKTVSAKYTMRYFALVGGSKTKQSFNLTETQIERKVLLSNPILEAFGNAKTIRNDNSSRFGKYLEILFNPRNQ-VIGANMCTYLLEKSRVVFQNLGERNYHIFYQIVTHCQSEDELLMNTGLVNNVEMYDYLRYGESLEIDGVDDSHEFLITKNSFLQLGIDLNKFKTICEILAAILHLGNIRFRFHDATDS-SIIENPELLKLIAGLLGCSIDQLKIWLCFRTISTFQETLHKPLSKAEAQYFRDAFVKTLYSNLFDWIVKQANKVLSTDVSINIKKKLKKTIVVNQEDKK-KFIAVLDIYGFETFAENSFEQFCINFANEKLQLQFNLHVFKLEQEEYMNEGLEWTFIDYYNNQPCIDLIESRXXXXXXXXXXXXXXXXSDENWCCKIY-SHHLNKSANFNKPKLSNMVFIIEHFAGPVEYKCAGFIEKNRDSVLEEQINLLKASDVQLIAELFRDSEIEIFDTNNXXXXXXXXXXXXXXXXXXQENTRKMKKTVGSQFRNSLKSLMDALNKTNPHYVRCIKPNDLKLPFTFCPERAVQQLRACGVLETIRLSAAGFPSRWTYSDFYHRYYILMSNFNVKNHDFKAGSQKIVETLITVPDAFRFGNTKLFFRPGQVALLEKLRGHKIESSVTLIQSILRGSIERKKYLIIHKLTVQIQTYIRRKLAIEKATKLSQIRAVIIIQSFYRMYLARKLFVKMKCAVLAIEKWRRKIITTRLKQAYKKENCVIICQAIVRRFIQRRKFLKIQRGVILIQNHYRRRKAKETLKILKIEARSINHIKFVNKGLENKIIELTQKLD---TKEKEMCXXXXXXXXXXXXXXXXXXXXXAESAKIYQ--NTVQDLQTEIIQLKKELNREIVEKNKIFADKELLEINYKKKINYLENLIEELKSSPSVIEPNIICNGDEAQQSICQDEHQKFINEQMDHQKLVREYEKLE--------MKYENLYKEFLFVKSSNQKPSINYDN---QTSNDSETESTFSKD 3460
+ KGV+IW VWIGAT+ + F I++ D + E + S PFLRNP L+G+ DLT LSYL+EP VL+NLQ+RF + IYTYCGIVLVAINPY + S IYG+EII Y +++ ++DPHIFAVAE A M +FG++QSIIVSGESGAGKTVSAK+ MRY A V SKT+ N T IE +VL SNPI+E+ GNAKTIRNDNSSRFGK+++I F R + ++GA M TYLLEKSR+VFQ GERNYHIFYQ+ C + + ++ + E Y YL G I GVDD +F + LG D + + +LA +L LGN+ F + + + S E+ +L S L+IWL R I E + KPL+K EA RDA K LYS+LF W+V + N+ L N K KL T NQ+ + +FI VLDIYGFETF NSFEQF IN+ANEKLQ QFN HVFKLEQEEY+ E +EW +D+++NQP IDLIE +G+++LLDE+CK L GSD +W ++ S L ++ PK+ + FI+ HFA V Y GF+EKNRD++ E+ ++++ AS I + + +S S S R +KKTV SQFR+SLK LM L T PHYVRCIKPND K+ F F P+RA+QQLRACGVLET+R+SAAGFPSR+ Y +F RY ++ + D ++ + G TK+F R GQVA+LE++R + ++ T+IQ + +G + R+KY + + + +Q ++ LA + L RAVI++QS R YL R+ + +++ +++ I+ + R + + E I QA R ++ RR+ + ++ V+++Q R+ AK L+ LKIEARS+ H++ +N GLENKIIEL +LD + KE K + +L + +AE + + N V+ LQ E+ +L+ E + + E + + +++E+ + +++ +++ +S +++E +A + + +E Q+ + ++ ++ R E MK +L++ F K +QK + + D+ TSN S+ +F+ +
Sbjct: 18 FKKGVRIWHRHPTLVWIGATLEEDITFQTRNVRIRLEDDTEV--EYAIKSLDQLPFLRNPAFLVGKDDLTLLSYLHEPAVLHNLQVRFVKGSSIYTYCGIVLVAINPYADCSHIYGEEIIQVYRGAGKSAREMDPHIFAVAEEAHFDMGAFGKSQSIIVSGESGAGKTVSAKFVMRYLASVAASKTR---NGGTTSIEARVLASNPIMESIGNAKTIRNDNSSRFGKFIQINFCERGRRIVGAEMKTYLLEKSRLVFQAPGERNYHIFYQL---CAARNHQVLKDLHLGPCESYSYLTQGGDSRIPGVDDKADFEALLKALQLLGFDEKQMSDVFRLLAGLLLLGNVHFENGEGSSAVSASSCQEISRLCREFWKISESDLRIWLTRREIRAVNEIVTKPLTKNEAVRSRDALTKMLYSHLFGWLVDKINEAL------NEKDKLDGT---NQKKRPDRFIGVLDIYGFETFDVNSFEQFSINYANEKLQQQFNQHVFKLEQEEYIREEIEWVRVDFHDNQPAIDLIEGPVGMINLLDEQCKRLNGSDADWLSQLQNSTELKRNPQLAFPKVRSNDFIVRHFAADVTYSTDGFVEKNRDAIGEQLLDVVVASKFPFIRTVI---------------GSTAPTSVSSSSSSSTPGKRTIKKTVASQFRDSLKELMSVLCSTRPHYVRCIKPNDSKISFDFEPKRAIQQLRACGVLETVRISAAGFPSRYPYEEFARRYRVIYTKEAALWRDKPKQFAELACQQCLEEGKYAVGKTKIFLRTGQVAVLERVRLDTLAAAATVIQKMWKGFLARRKYETMRRSLLIVQASLKAFLAFRRIKYLQMHRAVIVMQSAVRGYLERRKYEQIRDSIIGIQAMFKANRVRRYVEKLRYEKSAITIQAAWRGYLARREQIANRKKVVMVQCAVRKWLAKRRLRELKIEARSVGHLQKLNTGLENKIIELQMRLDIANARTKEEAEKFATASKNLQKTKADLAMMEAERLTLLEARNRVEVLQEEVERLETECD--LKEAQRGGMETKMVEL--QSRLDQMQS-----ESGQTIVELTEQLEKAKADRVLWDEERQR-MEAALNTERSARNALDAEMAAMREQLMKNVDLFESSTFQKRPSQKKNRDDDSCSRTTSNLSQLTGSFTAE 1133 HSP 2 Score: 100.523 bits (249), Expect = 1.119e-20 Identity = 112/460 (24.35%), Postives = 205/460 (44.57%), Query Frame = 2
Query: 4235 NDQIISETIELKRGLKYFAFRLQKYEGSLVPNPNKEEDLLQLIQNVIYHSKMKTIGKRECYSEIGLIDLNMSELSIFIKSFIFDLSPSICLQYEPYHLVPYIIFMVTRKFDFYKEEDQMTNFLSKLIVALKRTIRKRRNYIEYLVMLLSNVFCLVNLXXXXXXXXXXXXL---NTAEDIQHYFVHYDLNEFIRLLKELCVTLFQMILKTIVDNLLPQSLCIDAILVHEAIIDFLSKDGTKYKSN---IETQPKNTSFNVLTKNLQSVLEILKNHKIPQLIINQIFVHIAYLINAYCLNTLLFRTDLCYFSKGLQIKYNLSSFETWIRYQKLIDSGALQCLRPMTEAVQLLQTLIDSDEDAKFVCDMCEYLNTRQVVKILNNFNPRDGYGCRLSSGLIAKIETQM--KIKRGDEPSE--SKLETPTVIEIPIDI-PFIHNGVSLCRTIIPKPLYLSCLTVL 5581
ND++ ++ EL +L+ Y G L +E++++L +K G E Y N+ E F + + +L P++ + +L Y++ R D ++E +T S + + LK TI R + ++ L + L N++ L NL +QYSG NT + F YD+ LK + ++K ++++L + + IL HE+ D ++ + N +E+Q K S + L + ++ V L + +++ Q+ +A + A LN ++FR +LC F K +QIK+N++ + W+ + L D P+ +A LLQ+ D +M L RQVV IL +++P D LS + +I+ ++ + ++P E KL P D PF ++ L +P L++ + L
Sbjct: 1373 NDKLTRQSEELAEARA----QLRGYSGPLGLENASDEEIIRL--EAFEKGSIKHSGFLEVY--------NVPE---FARIIVCELKPTLA-RLLTKNLPAYLLVAAFRNHDEKRDETALTGLFSSVHLVLKDTI-SRSHDLDLLSLWLVNLWRLFNLLRQYSGEDSQPEWHVANTETQNSYRFKAYDVAPIRDQLKLRIEECYTSLMKKAIEHVLSPKI-VPGILQHESSSDLMTAGQERRDRNSGSVESQRK--SLDDLLQFMEIVHTKLTTYGGDDIVVKQVIGQMARWMCALALNYMMFRRELCNFEKAIQIKHNVTQIQNWLNAKGLSD--CRDHFEPLVQACHLLQSRKDPSNLDTLCGEMTSRLKPRQVVAILQHYDPSDEMEDGLSPEFLVQIQKKLNERAIANNDPIEDKDKLIMLGTYLPPFDTQPFSYSDFPLETLSLPSCLHMQSVCRL 1808
BLAST of Dach-2 vs. Ensembl Celegans
Match: myo-6 (MYOsin heavy chain structural genes [Source:UniProtKB/TrEMBL;Acc:Q5FC20]) HSP 1 Score: 449.899 bits (1156), Expect = 5.810e-133 Identity = 301/890 (33.82%), Postives = 478/890 (53.71%), Query Frame = 2
Query: 86 WIPDEESVWIGATVLQFHKEKNVIKIITDNGISKELNLSSKKCAPFLRNPDILIGQKDLTYLSYLNEPEVLYNLQIRFCERREIYTYCGIVLVAINPYQELSIYGKEIINAYHSQNSVDLDPHIFAVAENAFRRMSSFGENQSIIVSGESGAGKTVSAKYTMRYFALVGGSKTKQSFNLTETQIERKVLLSNPILEAFGNAKTIRNDNSSRFGKYLEILFNPRNQVIGANMCTYLLEKSRVVFQNLGERNYHIFYQIVTHCQSEDELLMNTGLVNNVEMYDYLRYGESLEIDGVDDSHEFLITKNSFLQLGIDLNKFKTICEILAAILHLGNIRFRFHDATDSSIIENPELLKLIAGLLGCSIDQLKIWLCFRTISTFQETLHKPLSKAEAQYFRDAFVKTLYSNLFDWIVKQANKVLSTDVSINIKKKLKKTIVVNQEDKKKFIAVLDIYGFETFAENSFEQFCINFANEKLQLQFNLHVFKLEQEEYMNEGLEWTFIDY-YNNQPCIDLIESRXXXXXXXXXXXXXXXXSDENWCCKIYSHHLNKSANFNKPKL-----SNMVFIIEHFAGPVEYKCAGFIEKNRDSVLEEQINLLKASDVQ-LIAELFRDSEIEIFDTNNXXXXXXXXXXXXXXXXXXQENTRKMKKTVGSQFRNSLKSLMDALNKTNPHYVRCIKPNDLKLPFTFCPERAVQQLRACGVLETIRLSAAGFPSRWTYSDFYHRYYILMSNFNVKNHDFKAGSQKIVETL-----ITVPDAFRFGNTKLFFRPGQVALLEKLRGHKIESSVTLIQSILRGSIERKKYLIIHKLTVQIQTYIRRKLAIEKATKLSQ--IRAVIIIQS--FYRMYLARKLFVKMKCAVLAIEKWRRKIITTRLKQAYKKE 2707
W+PD ++ A V +E + + +G K+L + + NP +D++ L++LNE VL+NL+ R+ IYTY G+ V INPY+ L IY + + Y ++ ++ PH+FAV++ AFR M S ENQS++++GESGAGKT + K + YFA++G Q +E+ +E +V+ +NP +EAFGN T RN NSSR+GK++ I F+ + +++G ++ YLLEKSRV+ Q GER+YHIFYQI+T + L GL +N+ Y ++ E + + G++D+ E+ IT +F +G + + ++ +AI+H+GN F+ + + +++ L G + DQ L I E ++K + + + A K +Y+ +F+W++K+ NK T+ N ++ +I VLDI GFE F NSFEQ INF NEKLQ FN H+F LEQEEY EG+EWTFID+ + Q CI+LIE LG++ +LDEEC + K SD + K+ + HL K NF K K + F I H+AG V Y +++KN+D + + + +LK SD + ++ +L+ + + ++ + K + S TV + +R SL SLM L+ T+PH++RCI PN+ K + QL GVLE IR+ GFP+R ++DF RY IL ++ + D S+ ++ L + V D F+ G TK+FFR G +A LE+LR + + + Q LR + + +Y +R+L E A + Q IRA I ++S +YR++ K +K + IE +K L++ +K+E
Sbjct: 38 WVPDAAEGFVTAAVAV--QEGDNLTFTMPDGTPKKLTRAEVQEI----NPAKFEKTEDMSNLTFLNEASVLHNLRQRYYSMM-IYTYSGLFCVFINPYKMLPIYTDSVASMYVNKRRAEMPPHLFAVSDEAFRNMMSDKENQSMLITGESGAGKTENTKKVIAYFAMIGSGNKDQK---SESSLENQVVQANPAIEAFGNGATTRNYNSSRYGKFIRIHFDRKGKLVGGDIEHYLLEKSRVIKQAPGERSYHIFYQIMT----QKALRERYGLSDNIRDYKFVSQAE-ITVPGMNDTEEWQITDGAFNVMGFSEREKDDLYKLCSAIMHIGNSTFKQKPRDEQAEVDDMTSPTAACKLFGINTDQFLNALTRPRIKVGMEWVNKGQNVQQVDWAVGALSKAIYARMFNWLIKRVNK----------------TLQANSDEMVYYIGVLDIAGFEIFDRNSFEQLWINFVNEKLQQFFNHHMFVLEQEEYQREGIEWTFIDFGLDLQSCIELIEKPLGIVSMLDEECIVPKASDMTYVDKLLTQHLGKHPNFQKAKPPKGKQAEAHFSIMHYAGTVRYNAEQWLDKNKDPLNDSAVAILKTSDKEGVLYQLWEEYQTDVDREESEKRGKAQAKKKGKSASFL---------TVSTMYRESLTSLMTMLHTTHPHFIRCIIPNEKKTSGLIDAPLVLNQLTCNGVLEGIRICRKGFPNRMMFADFRFRYAILAAD-EASDKDAAKASKAMLRKLSKNNQLNV-DTFKVGTTKVFFRAGMLARLEELRDEALSAVILKFQCSLRHYLAQLEY--------------KRRLDREDAYPIIQENIRAWIKLRSWPWYRLFSRLKPMLKGMKSNAEIEALEKKC--KELEENHKRE 869
BLAST of Dach-2 vs. Ensembl Celegans
Match: myo-1 (Myosin-1 [Source:UniProtKB/Swiss-Prot;Acc:P02567]) HSP 1 Score: 456.062 bits (1172), Expect = 5.494e-131 Identity = 307/877 (35.01%), Postives = 454/877 (51.77%), Query Frame = 2
Query: 65 YSKGVKIWIPDEESVWIGATVLQFHKEKNVIKIITDNGISKELNLSSKKCAPFLRNPDILIGQKDLTYLSYLNEPEVLYNLQIRFCERREIYTYCGIVLVAINPYQELSIYGKEIINAYHSQNSVDLDPHIFAVAENAFRRMSSFGENQSIIVSGESGAGKTVSAKYTMRYFALVGGS-KTKQSFNLTETQIERKVLLSNPILEAFGNAKTIRNDNSSRFGKYLEILFNPRNQVIGANMCTYLLEKSRVVFQNLGERNYHIFYQIVTH--CQSEDELLMNTGLVNNVEMYDYLRYGESLEIDGVDDSHEFLITKNSFLQLGIDLNKFKTICEILAAILHLGNIRFRFHDATDSSIIENPELLKLIAGLLGCSIDQLKIWLCFRTISTFQETLHKPLSKAEAQYFRDAFVKTLYSNLFDWIVKQANKVLSTDVSINIKKKLKKTIVVNQEDKKKFIAVLDIYGFETFAENSFEQFCINFANEKLQLQFNLHVFKLEQEEYMNEGLEWTFIDY-YNNQPCIDLIESRXXXXXXXXXXXXXXXXSDENWCCKIYSHHLNKSANFNKPK-----LSNMVFIIEHFAGPVEYKCAGFIEKNRDSVLEEQINLLKASDV-QLIAELFRDSEIEIFDTNNXXXXXXXXXXXXXXXXXXQENTRKMKKTVGSQFRNSLKSLMDALNKTNPHYVRCIKPNDLKLPFTFCPERAVQQLRACGVLETIRLSAAGFPSRWTYSDFYHRYYILMSNFNVKNHDFKAGSQKIVETLITV----PDAFRFGNTKLFFRPGQVALLEKLRGHKIESSVTLIQSILRGSIERKKYLIIHKLTVQIQTYIRRKLAIEKATKLSQIRAVIIIQSFYRMYLARKLFVKMKCAVLAIE 2653
Y +WIPD E +I + + + + I+T G K++ L KK NP +D++ L++LN+ VL+NL+ R+ IYTY G+ V INPY+ L IY + + + ++ PH+FAV++ A+R M ENQS++++GESGAGKT + K + YFA VG S K E +E +++ +NP+LEAFGNAKT+RN+NSSRFGK++ I FN + ++ YLLEKSRV+ Q GER YHIFYQI + Q DELL+N + N Y ++ E L IDG+DD+ EF +T +F L + +++A +H+GN++F+ + + + + + + G +DQ L + E + K + + + A K LY+ +F W+VK+ N L +K I D+ FI VLDI GFE F NSFEQ INF NEKLQ FN H+F LEQEEY EG++WTFID+ + Q CI+LIE LG++ +LDEEC + K +D K+ HL K NF KPK F + H+AG V Y ++EKN+D + + ++++KAS L+ E+++D + T + + TV +R SL LM L+KT+PH++RCI PN+ K + QL GVLE IR+ GFP+R + DF RY IL + + D K + I++ LI + FR G+TK+FF+ G VA +E LR K+ +T QS +R T RRK IR+ +++++ L KL ++KC +A E
Sbjct: 29 YDSKKNVWIPDAEEGYIEGVIKGPGPKADTV-IVTAGG--KDVTL--KKDIVQEVNPPKFEKTEDMSNLTFLNDASVLWNLRSRYAAML-IYTYSGLFCVVINPYKRLPIYTDSVARMFMGKRRTEMPPHLFAVSDQAYRYMLQDHENQSMLITGESGAGKTENTKKVICYFATVGASQKAALKEGEKEVTLEDQIVQTNPVLEAFGNAKTVRNNNSSRFGKFIRIHFNKHGTLASCDIEHYLLEKSRVIRQAPGERCYHIFYQIYSDFKPQLRDELLLNHPISN----YWFVAQAELL-IDGIDDTEEFQLTDEAFDVLKFSPTEKMDCYRLMSAHMHMGNMKFKQRPREEQAEPDGQDEAERACNMYGIDVDQFLKALVSPRVKVGTEWVSKGQNVDQVHWAIGAMAKGLYARVFHWLVKKCNLTLD-----------QKGI-----DRDYFIGVLDIAGFEIFDFNSFEQLWINFVNEKLQQFFNHHMFVLEQEEYAREGIQWTFIDFGLDLQACIELIEKPLGIISMLDEECIVPKATDMTLAQKLTDQHLGKHPNFEKPKPPKGKQGEAHFAMRHYAGTVRYNVLNWLEKNKDPLNDTVVSVMKASKKNDLLVEIWQD-----YTTQEEAAAAAKAGGGRKGG------KSGSFMTVSMMYRESLNKLMTMLHKTHPHFIRCIIPNEKKQSGMIDAALVLNQLTCNGVLEGIRICRKGFPNRTQHPDFVQRYAILAAKEAKSSDDMKTCAGAILQALINQKQLNDEQFRIGHTKVFFKAGVVAHIEDLRDDKLNQIITGFQSAIRW------------YTATADAGARRKQLNSYIILQRNIRSWCVLRTWDWFLLFGKLRPQLKCGKMAEE 855
BLAST of Dach-2 vs. Ensembl Celegans
Match: myo-1 (Myosin-1 [Source:UniProtKB/Swiss-Prot;Acc:P02567]) HSP 1 Score: 456.062 bits (1172), Expect = 5.494e-131 Identity = 307/877 (35.01%), Postives = 454/877 (51.77%), Query Frame = 2
Query: 65 YSKGVKIWIPDEESVWIGATVLQFHKEKNVIKIITDNGISKELNLSSKKCAPFLRNPDILIGQKDLTYLSYLNEPEVLYNLQIRFCERREIYTYCGIVLVAINPYQELSIYGKEIINAYHSQNSVDLDPHIFAVAENAFRRMSSFGENQSIIVSGESGAGKTVSAKYTMRYFALVGGS-KTKQSFNLTETQIERKVLLSNPILEAFGNAKTIRNDNSSRFGKYLEILFNPRNQVIGANMCTYLLEKSRVVFQNLGERNYHIFYQIVTH--CQSEDELLMNTGLVNNVEMYDYLRYGESLEIDGVDDSHEFLITKNSFLQLGIDLNKFKTICEILAAILHLGNIRFRFHDATDSSIIENPELLKLIAGLLGCSIDQLKIWLCFRTISTFQETLHKPLSKAEAQYFRDAFVKTLYSNLFDWIVKQANKVLSTDVSINIKKKLKKTIVVNQEDKKKFIAVLDIYGFETFAENSFEQFCINFANEKLQLQFNLHVFKLEQEEYMNEGLEWTFIDY-YNNQPCIDLIESRXXXXXXXXXXXXXXXXSDENWCCKIYSHHLNKSANFNKPK-----LSNMVFIIEHFAGPVEYKCAGFIEKNRDSVLEEQINLLKASDV-QLIAELFRDSEIEIFDTNNXXXXXXXXXXXXXXXXXXQENTRKMKKTVGSQFRNSLKSLMDALNKTNPHYVRCIKPNDLKLPFTFCPERAVQQLRACGVLETIRLSAAGFPSRWTYSDFYHRYYILMSNFNVKNHDFKAGSQKIVETLITV----PDAFRFGNTKLFFRPGQVALLEKLRGHKIESSVTLIQSILRGSIERKKYLIIHKLTVQIQTYIRRKLAIEKATKLSQIRAVIIIQSFYRMYLARKLFVKMKCAVLAIE 2653
Y +WIPD E +I + + + + I+T G K++ L KK NP +D++ L++LN+ VL+NL+ R+ IYTY G+ V INPY+ L IY + + + ++ PH+FAV++ A+R M ENQS++++GESGAGKT + K + YFA VG S K E +E +++ +NP+LEAFGNAKT+RN+NSSRFGK++ I FN + ++ YLLEKSRV+ Q GER YHIFYQI + Q DELL+N + N Y ++ E L IDG+DD+ EF +T +F L + +++A +H+GN++F+ + + + + + + G +DQ L + E + K + + + A K LY+ +F W+VK+ N L +K I D+ FI VLDI GFE F NSFEQ INF NEKLQ FN H+F LEQEEY EG++WTFID+ + Q CI+LIE LG++ +LDEEC + K +D K+ HL K NF KPK F + H+AG V Y ++EKN+D + + ++++KAS L+ E+++D + T + + TV +R SL LM L+KT+PH++RCI PN+ K + QL GVLE IR+ GFP+R + DF RY IL + + D K + I++ LI + FR G+TK+FF+ G VA +E LR K+ +T QS +R T RRK IR+ +++++ L KL ++KC +A E
Sbjct: 29 YDSKKNVWIPDAEEGYIEGVIKGPGPKADTV-IVTAGG--KDVTL--KKDIVQEVNPPKFEKTEDMSNLTFLNDASVLWNLRSRYAAML-IYTYSGLFCVVINPYKRLPIYTDSVARMFMGKRRTEMPPHLFAVSDQAYRYMLQDHENQSMLITGESGAGKTENTKKVICYFATVGASQKAALKEGEKEVTLEDQIVQTNPVLEAFGNAKTVRNNNSSRFGKFIRIHFNKHGTLASCDIEHYLLEKSRVIRQAPGERCYHIFYQIYSDFKPQLRDELLLNHPISN----YWFVAQAELL-IDGIDDTEEFQLTDEAFDVLKFSPTEKMDCYRLMSAHMHMGNMKFKQRPREEQAEPDGQDEAERACNMYGIDVDQFLKALVSPRVKVGTEWVSKGQNVDQVHWAIGAMAKGLYARVFHWLVKKCNLTLD-----------QKGI-----DRDYFIGVLDIAGFEIFDFNSFEQLWINFVNEKLQQFFNHHMFVLEQEEYAREGIQWTFIDFGLDLQACIELIEKPLGIISMLDEECIVPKATDMTLAQKLTDQHLGKHPNFEKPKPPKGKQGEAHFAMRHYAGTVRYNVLNWLEKNKDPLNDTVVSVMKASKKNDLLVEIWQD-----YTTQEEAAAAAKAGGGRKGG------KSGSFMTVSMMYRESLNKLMTMLHKTHPHFIRCIIPNEKKQSGMIDAALVLNQLTCNGVLEGIRICRKGFPNRTQHPDFVQRYAILAAKEAKSSDDMKTCAGAILQALINQKQLNDEQFRIGHTKVFFKAGVVAHIEDLRDDKLNQIITGFQSAIRW------------YTATADAGARRKQLNSYIILQRNIRSWCVLRTWDWFLLFGKLRPQLKCGKMAEE 855
BLAST of Dach-2 vs. Ensembl Fly
Match: didum (gene:FBgn0261397 transcript:FBtr0089744) HSP 1 Score: 780.015 bits (2013), Expect = 0.000e+0 Identity = 446/969 (46.03%), Postives = 612/969 (63.16%), Query Frame = 2
Query: 62 MYSKGVKIWIPDEESVWIGATVLQ-FHKEKNVIKIITDNGISKELNLSSKKC-APFLRNPDILIGQKDLTYLSYLNEPEVLYNLQIRFCERREIYTYCGIVLVAINPYQELSIYGKEIINAYHSQNSVDLDPHIFAVAENAFRRMSSFGENQSIIVSGESGAGKTVSAKYTMRYFALVGGSKTKQSFNLTETQIERKVLLSNPILEAFGNAKTIRNDNSSRFGKYLEILFNPRNQVI---GANMCTYLLEKSRVVFQNLGERNYHIFYQIVTHCQSEDELLMNTGLVNNVEMYDYLRYGESLEIDGVDDSHEFLITKNSFLQLGIDLNKFKTICEILAAILHLGNIRF--RFH------DATDSSIIENPELLKLIAGLLGCSIDQLKIWLCFRTISTFQETLHKPLSKAEAQYFRDAFVKTLYSNLFDWIVKQANKVLSTDVSINIKKKLKKTIVVNQEDKKKFIAVLDIYGFETFAENSFEQFCINFANEKLQLQFNLHVFKLEQEEYMNEGLEWTFIDYYNNQPCIDLIESRXXXXXXXXXXXXXXXXSDENWCCKIYSHHLNKSANFNKPKLSNMVFIIEHFAGPVEYKCAGFIEKNRDSVLEEQINLLKASDVQLIAELFRDSEIEIFDTNNXXXXXXXXXXXXXXXXXXQENTRKMKKTVGSQFRNSLKSLMDALNKTNPHYVRCIKPNDLKLPFTFCPERAVQQLRACGVLETIRLSAAGFPSRWTYSDFYHRYYILMSNFNVKNHDFKAGSQKIVETLITVPDAFRFGNTKLFFRPGQVALLEKLRGHKIESSVTLIQSILRGSIERKKYLIIHKLTVQIQTYIRRKLAIEKATKLSQIRAVIIIQSFYRMYLARKLFVKMKCAVLAIEKWRRKIITTRLKQAYKKENCVIICQAIVRRFIQRRKFLKIQRGVILIQNHYRRRKAKETLKILKIEARSINHIKFVNKGLENKIIELTQKLD 2929
+Y++G KIW+P + VW AT+ + + K +KI TD+G KE+ L + P LRNP IL+GQ DLT LSYL+EP VL+NL++RFCER+ IYTYCGI+LVAINPY E+ +YG II AY DL+PHIFA+AE A+ ++ N SIIVSGESGAGKTVSAKY MRYFA VGGS++ ETQ+ERKVL S+PI+EAFGNAKT RNDNSSRFGK+ ++LF + V+ GA M TYLLEKSRVV+Q GERNYHIFYQ+ EL+++ + + + +L G + EI+ V D+ +F T + LG + + I +ILA ILHLGNI+ +F+ D+ I N L++ A LL S D L+ WL R I + E + P S AQ RDA K +Y+ LF +IV NK L+ N + FI VLDIYGFETF NSFEQFCIN+ANEKLQ QFN HVFKLEQEEY+ EG+ WT ID+Y+NQPCIDLIESRLG+LDLLDEEC++ KGSDE+W K+ NK +F KP+ F I+HF+ VEY GF+EKNRD+V +E +L S++ L ++ EI+ +++K S + +++ +KTVGSQF+ SL SL+ L+ T PHYVRCIKPND K+ F + + +QQLRACGVLET+R+SAAGFPSRW Y DFY RY +L+ + +D K + IV I D +RFGNT++FFR GQVA LE++R + + +T++QS++R + R+++L I K+ IQ + R LA E+ K+ + RA +I+ + R +L R+ +++++ ++ I+ + R ++ A + + Q VR + RR + K +R +I+ Q RR A+ K +K EA++I+H++ GLENKII + Q++D
Sbjct: 7 LYAQGAKIWVPHADLVWESATLEESYRKGAGFLKICTDSGKLKEVKLKADGSDLPPLRNPAILVGQNDLTTLSYLHEPGVLHNLRVRFCERQIIYTYCGIILVAINPYAEMPLYGPSIIRAYRGHAMGDLEPHIFALAEEAYTKLERENCNLSIIVSGESGAGKTVSAKYAMRYFAAVGGSES-------ETQVERKVLASSPIMEAFGNAKTTRNDNSSRFGKFTKLLFRNQMGVMFLQGATMHTYLLEKSRVVYQAQGERNYHIFYQLCAARSKYPELVLD-----HQDKFQFLNMGGAPEIERVSDAEQFNETVQAMTVLGFSIQQIADIVKILAGILHLGNIQVSKKFNEGSEEEDSDSCDIFHNDIHLQITADLLRVSADDLRRWLLMRKIESVNEYVLIPNSIEAAQAARDALAKHIYAKLFQYIVGVLNKSLN-----------------NGSKQCSFIGVLDIYGFETFEVNSFEQFCINYANEKLQQQFNQHVFKLEQEEYLKEGITWTMIDFYDNQPCIDLIESRLGVLDLLDEECRMPKGSDESWAGKLIGK-CNKFPHFEKPRFGTTSFFIKHFSDTVEYDVNGFLEKNRDTVSKELTQVLSESNMSLAKQVMTLEEIDTLCVDSAKSSTLGGRVVISAGRKQVVPSKQHRKTVGSQFQESLASLISTLHATTPHYVRCIKPNDDKVAFKWETAKIIQQLRACGVLETVRISAAGFPSRWLYPDFYMRYQLLVYRSKLDKNDMKLSCRNIVMKWIQDEDKYRFGNTQIFFRAGQVAFLEQVRANLRKKYITIVQSVVRRFVYRRQFLRIQKVINGIQKHARGYLARERTQKMREARAGLILSKYARGWLCRRRYLRLRHSISGIQTYARGMLARNKFHAMRDHYRAVQIQRFVRGALARRAYQKRRRNIIICQAAIRRFLARRKFKRMKAEAKTISHMENKYMGLENKIISMQQRID 945
BLAST of Dach-2 vs. Ensembl Fly
Match: didum (gene:FBgn0261397 transcript:FBtr0089745) HSP 1 Score: 779.245 bits (2011), Expect = 0.000e+0 Identity = 446/969 (46.03%), Postives = 612/969 (63.16%), Query Frame = 2
Query: 62 MYSKGVKIWIPDEESVWIGATVLQ-FHKEKNVIKIITDNGISKELNLSSKKCA-PFLRNPDILIGQKDLTYLSYLNEPEVLYNLQIRFCERREIYTYCGIVLVAINPYQELSIYGKEIINAYHSQNSVDLDPHIFAVAENAFRRMSSFGENQSIIVSGESGAGKTVSAKYTMRYFALVGGSKTKQSFNLTETQIERKVLLSNPILEAFGNAKTIRNDNSSRFGKYLEILFNPRNQVI---GANMCTYLLEKSRVVFQNLGERNYHIFYQIVTHCQSEDELLMNTGLVNNVEMYDYLRYGESLEIDGVDDSHEFLITKNSFLQLGIDLNKFKTICEILAAILHLGNIRF--RFH------DATDSSIIENPELLKLIAGLLGCSIDQLKIWLCFRTISTFQETLHKPLSKAEAQYFRDAFVKTLYSNLFDWIVKQANKVLSTDVSINIKKKLKKTIVVNQEDKKKFIAVLDIYGFETFAENSFEQFCINFANEKLQLQFNLHVFKLEQEEYMNEGLEWTFIDYYNNQPCIDLIESRXXXXXXXXXXXXXXXXSDENWCCKIYSHHLNKSANFNKPKLSNMVFIIEHFAGPVEYKCAGFIEKNRDSVLEEQINLLKASDVQLIAELFRDSEIEIFDTNNXXXXXXXXXXXXXXXXXXQENTRKMKKTVGSQFRNSLKSLMDALNKTNPHYVRCIKPNDLKLPFTFCPERAVQQLRACGVLETIRLSAAGFPSRWTYSDFYHRYYILMSNFNVKNHDFKAGSQKIVETLITVPDAFRFGNTKLFFRPGQVALLEKLRGHKIESSVTLIQSILRGSIERKKYLIIHKLTVQIQTYIRRKLAIEKATKLSQIRAVIIIQSFYRMYLARKLFVKMKCAVLAIEKWRRKIITTRLKQAYKKENCVIICQAIVRRFIQRRKFLKIQRGVILIQNHYRRRKAKETLKILKIEARSINHIKFVNKGLENKIIELTQKLD 2929
+Y++G KIW+P + VW AT+ + + K +KI TD+G KE+ L + P LRNP IL+GQ DLT LSYL+EP VL+NL++RFCER+ IYTYCGI+LVAINPY E+ +YG II AY DL+PHIFA+AE A+ ++ N SIIVSGESGAGKTVSAKY MRYFA VGGS++ ETQ+ERKVL S+PI+EAFGNAKT RNDNSSRFGK+ ++LF + V+ GA M TYLLEKSRVV+Q GERNYHIFYQ+ EL+++ + + + +L G + EI+ V D+ +F T + LG + + I +ILA ILHLGNI+ +F+ D+ I N L++ A LL S D L+ WL R I + E + P S AQ RDA K +Y+ LF +IV NK L+ N + FI VLDIYGFETF NSFEQFCIN+ANEKLQ QFN HVFKLEQEEY+ EG+ WT ID+Y+NQPCIDLIESRLG+LDLLDEEC++ KGSDE+W K+ NK +F KP+ F I+HF+ VEY GF+EKNRD+V +E +L S++ L ++ EI+ +++K S + +++ +KTVGSQF+ SL SL+ L+ T PHYVRCIKPND K+ F + + +QQLRACGVLET+R+SAAGFPSRW Y DFY RY +L+ + +D K + IV I D +RFGNT++FFR GQVA LE++R + + +T++QS++R + R+++L I K+ IQ + R LA E+ K+ + RA +I+ + R +L R+ +++++ ++ I+ + R ++ A + + Q VR + RR + K +R +I+ Q RR A+ K +K EA++I+H++ GLENKII + Q++D
Sbjct: 7 LYAQGAKIWVPHADLVWESATLEESYRKGAGFLKICTDSGKLKEVKLKADGSDLPPLRNPAILVGQNDLTTLSYLHEPGVLHNLRVRFCERQIIYTYCGIILVAINPYAEMPLYGPSIIRAYRGHAMGDLEPHIFALAEEAYTKLERENCNLSIIVSGESGAGKTVSAKYAMRYFAAVGGSES-------ETQVERKVLASSPIMEAFGNAKTTRNDNSSRFGKFTKLLFRNQMGVMFLQGATMHTYLLEKSRVVYQAQGERNYHIFYQLCAARSKYPELVLD-----HQDKFQFLNMGGAPEIERVSDAEQFNETVQAMTVLGFSIQQIADIVKILAGILHLGNIQVSKKFNEGSEEEDSDSCDIFHNDIHLQITADLLRVSADDLRRWLLMRKIESVNEYVLIPNSIEAAQAARDALAKHIYAKLFQYIVGVLNKSLN-----------------NGSKQCSFIGVLDIYGFETFEVNSFEQFCINYANEKLQQQFNQHVFKLEQEEYLKEGITWTMIDFYDNQPCIDLIESRLGVLDLLDEECRMPKGSDESWAGKLIGK-CNKFPHFEKPRFGTTSFFIKHFSDTVEYDVNGFLEKNRDTVSKELTQVLSESNMSLAKQVMTLEEIDTLCVDSAKSSTLGGRVVISAGRKQVVPSKQHRKTVGSQFQESLASLISTLHATTPHYVRCIKPNDDKVAFKWETAKIIQQLRACGVLETVRISAAGFPSRWLYPDFYMRYQLLVYRSKLDKNDMKLSCRNIVMKWIQDEDKYRFGNTQIFFRAGQVAFLEQVRANLRKKYITIVQSVVRRFVYRRQFLRIQKVINGIQKHARGYLARERTQKMREARAGLILSKYARGWLCRRRYLRLRHSISGIQTYARGMLARNKFHAMRDHYRAVQIQRFVRGALARRAYQKRRRNIIICQAAIRRFLARRKFKRMKAEAKTISHMENKYMGLENKIISMQQRID 945
BLAST of Dach-2 vs. Ensembl Fly
Match: didum (gene:FBgn0261397 transcript:FBtr0089743) HSP 1 Score: 778.089 bits (2008), Expect = 0.000e+0 Identity = 448/977 (45.85%), Postives = 614/977 (62.85%), Query Frame = 2
Query: 62 MYSKGVKIWIPDEESVWIGATVLQ-FHKEKNVIKIITDNGISKELNLSSKKCA-PFLRNPDILIGQKDLTYLSYLNEPEVLYNLQIRFCERREIYTYCGIVLVAINPYQELSIYGKEIINAYHSQNSVDLDPHIFAVAENAFRRMSSFGENQSIIVSGESGAGKTVSAKYTMRYFALVGGSKTKQSFNLTETQIERKVLLSNPILEAFGNAKTIRNDNSSRFGKYLEILFNPRNQVI---GANMCTYLLEKSRVVFQNLGERNYHIFYQIVTHCQSEDELLMNTGLVNNVEMYDYLRYGESLEIDGVDDSHEFLITKNSFLQLGIDLNKFKTICEILAAILHLGNIRF--RFH------DATDSSIIENPELLKLIAGLLGCSIDQLKIWLCFRTISTFQETLHKPLSKAEAQYFRDAFVKTLYSNLFDWIVKQANKVLSTDVSINIKKKLKKTIVVNQEDKKKFIAVLDIYGFETFAENSFEQFCINFANEKLQLQFNLHVFKLEQEEYMNEGLEWTFIDYYNNQPCIDLIESRXXXXXXXXXXXXXXXXSDENWCCKIYSHHLNKSANFNKPKLSNMVFIIEHFAGPVEYKCAGFIEKNRDSVLEEQINLLKASDVQLIAELFRDSEIEIFDTNNXXXXXXXXXXXXXXXXXXQEN--------TRKMKKTVGSQFRNSLKSLMDALNKTNPHYVRCIKPNDLKLPFTFCPERAVQQLRACGVLETIRLSAAGFPSRWTYSDFYHRYYILMSNFNVKNHDFKAGSQKIVETLITVPDAFRFGNTKLFFRPGQVALLEKLRGHKIESSVTLIQSILRGSIERKKYLIIHKLTVQIQTYIRRKLAIEKATKLSQIRAVIIIQSFYRMYLARKLFVKMKCAVLAIEKWRRKIITTRLKQAYKKENCVIICQAIVRRFIQRRKFLKIQRGVILIQNHYRRRKAKETLKILKIEARSINHIKFVNKGLENKIIELTQKLD 2929
+Y++G KIW+P + VW AT+ + + K +KI TD+G KE+ L + P LRNP IL+GQ DLT LSYL+EP VL+NL++RFCER+ IYTYCGI+LVAINPY E+ +YG II AY DL+PHIFA+AE A+ ++ N SIIVSGESGAGKTVSAKY MRYFA VGGS++ ETQ+ERKVL S+PI+EAFGNAKT RNDNSSRFGK+ ++LF + V+ GA M TYLLEKSRVV+Q GERNYHIFYQ+ EL+++ + + + +L G + EI+ V D+ +F T + LG + + I +ILA ILHLGNI+ +F+ D+ I N L++ A LL S D L+ WL R I + E + P S AQ RDA K +Y+ LF +IV NK L+ N + FI VLDIYGFETF NSFEQFCIN+ANEKLQ QFN HVFKLEQEEY+ EG+ WT ID+Y+NQPCIDLIESRLG+LDLLDEEC++ KGSDE+W K+ NK +F KP+ F I+HF+ VEY GF+EKNRD+V +E +L S++ L ++ EI+ +++K S +Q N +++ +KTVGSQF+ SL SL+ L+ T PHYVRCIKPND K+ F + + +QQLRACGVLET+R+SAAGFPSRW Y DFY RY +L+ + +D K + IV I D +RFGNT++FFR GQVA LE++R + + +T++QS++R + R+++L I K+ IQ + R LA E+ K+ + RA +I+ + R +L R+ +++++ ++ I+ + R ++ A + + Q VR + RR + K +R +I+ Q RR A+ K +K EA++I+H++ GLENKII + Q++D
Sbjct: 7 LYAQGAKIWVPHADLVWESATLEESYRKGAGFLKICTDSGKLKEVKLKADGSDLPPLRNPAILVGQNDLTTLSYLHEPGVLHNLRVRFCERQIIYTYCGIILVAINPYAEMPLYGPSIIRAYRGHAMGDLEPHIFALAEEAYTKLERENCNLSIIVSGESGAGKTVSAKYAMRYFAAVGGSES-------ETQVERKVLASSPIMEAFGNAKTTRNDNSSRFGKFTKLLFRNQMGVMFLQGATMHTYLLEKSRVVYQAQGERNYHIFYQLCAARSKYPELVLD-----HQDKFQFLNMGGAPEIERVSDAEQFNETVQAMTVLGFSIQQIADIVKILAGILHLGNIQVSKKFNEGSEEEDSDSCDIFHNDIHLQITADLLRVSADDLRRWLLMRKIESVNEYVLIPNSIEAAQAARDALAKHIYAKLFQYIVGVLNKSLN-----------------NGSKQCSFIGVLDIYGFETFEVNSFEQFCINYANEKLQQQFNQHVFKLEQEEYLKEGITWTMIDFYDNQPCIDLIESRLGVLDLLDEECRMPKGSDESWAGKLIGK-CNKFPHFEKPRFGTTSFFIKHFSDTVEYDVNGFLEKNRDTVSKELTQVLSESNMSLAKQVMTLEEIDTLCVDSAKSSTLGGRVVISAGRKQQGNDTRRRVVPSKQHRKTVGSQFQESLASLISTLHATTPHYVRCIKPNDDKVAFKWETAKIIQQLRACGVLETVRISAAGFPSRWLYPDFYMRYQLLVYRSKLDKNDMKLSCRNIVMKWIQDEDKYRFGNTQIFFRAGQVAFLEQVRANLRKKYITIVQSVVRRFVYRRQFLRIQKVINGIQKHARGYLARERTQKMREARAGLILSKYARGWLCRRRYLRLRHSISGIQTYARGMLARNKFHAMRDHYRAVQIQRFVRGALARRAYQKRRRNIIICQAAIRRFLARRKFKRMKAEAKTISHMENKYMGLENKIISMQQRID 953
BLAST of Dach-2 vs. Ensembl Fly
Match: Myo28B1 (gene:FBgn0040299 transcript:FBtr0079476) HSP 1 Score: 456.447 bits (1173), Expect = 3.573e-137 Identity = 296/816 (36.27%), Postives = 434/816 (53.19%), Query Frame = 2
Query: 254 KDLTYLSYLNEPEVLYNLQIRFCERREIYTYCGIVLVAINPYQELSIYGKEIINAYHSQNSVDLDPHIFAVAENAFRRMSSFGENQSIIVSGESGAGKTVSAKYTMRYFALVGGSKTKQSFNLTETQIERKVLLSNPILEAFGNAKTIRNDNSSRFGKYLEILFNPRNQVIGANMCTYLLEKSRVVFQNLGERNYHIFYQIVTHCQSEDELLMNTGLVNNVEMYDYLRYGESLEIDGVDDSHEFLITKNSFLQLGIDLNKFKTICEILAAILHLGNIRFRFHDATD--SSIIENPELLKLIAGLLGCSIDQLKIWLCFRTISTFQETLHKPLSKAEAQYFRDAFVKTLYSNLFDWIVKQANKVLSTDVSINIKKKLKKTIVVNQEDKKKFIAVLDIYGFETFAENSFEQFCINFANEKLQLQFNLHVFKLEQEEYMNEGLEWTFIDYYNNQPCIDLIESRXXXXXXXXXXXXX-XXXSDENWCCKIYSHHLNKSANFNKPKLSNMVFIIEHFAGPVEYKCAGFIEKNRDSVLEEQINLLKASDVQLIAELFRDSEIEIFDTNNXXXXXXXXXXXXXXXXXXQENTRKMKKTVGSQFRNSLKSLMDALNKTNPHYVRCIKPNDLKLPFTFCPERAVQQLRACGVLETIRLSAAGFPSRWTYSDFYHRYYILMSNFN-VKNHDFKAGSQKIVETLITVPDAFRFGNTKLFFRPGQVALLEKLRGHKIESSVTLIQSILRGSIERKKYLIIHKLTVQIQTYIRRKL--------------------AIEKATKLSQIRA-VIIIQSFYRMYLARKLFVK 2626
+D+ L L E +L NLQ R+ ++ IYTY G +LVAINPYQ L IY I Y +++ +L PHIFA+++NAF+R+ ENQ +++SGESGAGKT S K ++Y A + G K S+ IE++++ +NPI+EAFGNAKT+RNDNSSRFGKY+EI F P+ + GA + YLLEKSR+VFQ+ ERNYHIFY ++ + + + + Y YL G + G D+ +F + + L + +I +LAAILHLGN+RF + + ++ I++ L+ +A LLG I L L RTI E + LSK A RDAFVK+LY +F IV++ N+ ++ V + I VLDI+GFE F NSFEQ CIN+ANE LQ F H+FK+EQ+EY NE + W I++ +NQ +DLI + L L +E KG+D+ K++ H N+S +F I H+AG V Y GF+EKNRDS + L++ S + + ++F E+ + +T K + T+ +FRNSL LM L++ +P+++RCIKPN+ K P F E V+QLR G++ET R+ AG+P R Y F RY +L+ ++ D + +++I E + ++G TKLF R A LE R + S+ IQ +R + R+ + + +Q Y R +L A + TK + +R I +Q+ R YL RK F K
Sbjct: 69 EDMITLGDLQEYTILRNLQNRYA-KQLIYTYTGSMLVAINPYQILPIYTNREIQLYRNKSLAELPPHIFAISDNAFQRLQRLKENQCVVISGESGAGKTESTKLILQYLAAISG---KHSW------IEQQIIEANPIMEAFGNAKTVRNDNSSRFGKYIEIRFTPQGAIQGARIQQYLLEKSRIVFQSRDERNYHIFYCMLAGLSTAERERLKLQ-EQSPSQYHYLAQGGCFTLPGRGDAKDFADIRAAMKVLSFKPEEVWSILSLLAAILHLGNLRFTATEVANLATAEIDDTPNLQRVAQLLGIPISALNAALTQRTIFVHGEHVTTSLSKEAAIEGRDAFVKSLYDGIFVRIVRRINETINKQVDQPMNS----------------IGVLDIFGFENFDNNSFEQLCINYANENLQQFFVGHIFKMEQDEYQNEHINWQHIEFQDNQQILDLIGMKPMNLMSLIDEESKFPKGTDQTLLEKLHVQHGNRSIYVKGKTTQTSLFGIRHYAGVVMYNPLGFLEKNRDSFSGDLRTLVQRSTNKYLVDIF-PHEMPM-------------------------DTAKKQPTLCVKFRNSLDMLMRTLSQAHPYFIRCIKPNEYKEPKNFDKELCVRQLRYSGMMETARIRRAGYPIRHAYRAFVERYRLLVPPVGPLEQCDCRKLARQICEVALPADSDRQYGKTKLFLRDEDDASLELQRSQLMLKSIVTIQRGIRRVLFRRYMKRYREAIITVQRYWRGRLQRRKYQVMRQGFHRLGACIAAQQLTTKFTMVRCRTIKLQALSRGYLVRKDFQK 831
BLAST of Dach-2 vs. Ensembl Fly
Match: Myo28B1 (gene:FBgn0040299 transcript:FBtr0079474) HSP 1 Score: 456.447 bits (1173), Expect = 4.197e-137 Identity = 296/816 (36.27%), Postives = 434/816 (53.19%), Query Frame = 2
Query: 254 KDLTYLSYLNEPEVLYNLQIRFCERREIYTYCGIVLVAINPYQELSIYGKEIINAYHSQNSVDLDPHIFAVAENAFRRMSSFGENQSIIVSGESGAGKTVSAKYTMRYFALVGGSKTKQSFNLTETQIERKVLLSNPILEAFGNAKTIRNDNSSRFGKYLEILFNPRNQVIGANMCTYLLEKSRVVFQNLGERNYHIFYQIVTHCQSEDELLMNTGLVNNVEMYDYLRYGESLEIDGVDDSHEFLITKNSFLQLGIDLNKFKTICEILAAILHLGNIRFRFHDATD--SSIIENPELLKLIAGLLGCSIDQLKIWLCFRTISTFQETLHKPLSKAEAQYFRDAFVKTLYSNLFDWIVKQANKVLSTDVSINIKKKLKKTIVVNQEDKKKFIAVLDIYGFETFAENSFEQFCINFANEKLQLQFNLHVFKLEQEEYMNEGLEWTFIDYYNNQPCIDLIESRXXXXXXXXXXXXX-XXXSDENWCCKIYSHHLNKSANFNKPKLSNMVFIIEHFAGPVEYKCAGFIEKNRDSVLEEQINLLKASDVQLIAELFRDSEIEIFDTNNXXXXXXXXXXXXXXXXXXQENTRKMKKTVGSQFRNSLKSLMDALNKTNPHYVRCIKPNDLKLPFTFCPERAVQQLRACGVLETIRLSAAGFPSRWTYSDFYHRYYILMSNFN-VKNHDFKAGSQKIVETLITVPDAFRFGNTKLFFRPGQVALLEKLRGHKIESSVTLIQSILRGSIERKKYLIIHKLTVQIQTYIRRKL--------------------AIEKATKLSQIRA-VIIIQSFYRMYLARKLFVK 2626
+D+ L L E +L NLQ R+ ++ IYTY G +LVAINPYQ L IY I Y +++ +L PHIFA+++NAF+R+ ENQ +++SGESGAGKT S K ++Y A + G K S+ IE++++ +NPI+EAFGNAKT+RNDNSSRFGKY+EI F P+ + GA + YLLEKSR+VFQ+ ERNYHIFY ++ + + + + Y YL G + G D+ +F + + L + +I +LAAILHLGN+RF + + ++ I++ L+ +A LLG I L L RTI E + LSK A RDAFVK+LY +F IV++ N+ ++ V + I VLDI+GFE F NSFEQ CIN+ANE LQ F H+FK+EQ+EY NE + W I++ +NQ +DLI + L L +E KG+D+ K++ H N+S +F I H+AG V Y GF+EKNRDS + L++ S + + ++F E+ + +T K + T+ +FRNSL LM L++ +P+++RCIKPN+ K P F E V+QLR G++ET R+ AG+P R Y F RY +L+ ++ D + +++I E + ++G TKLF R A LE R + S+ IQ +R + R+ + + +Q Y R +L A + TK + +R I +Q+ R YL RK F K
Sbjct: 70 EDMITLGDLQEYTILRNLQNRYA-KQLIYTYTGSMLVAINPYQILPIYTNREIQLYRNKSLAELPPHIFAISDNAFQRLQRLKENQCVVISGESGAGKTESTKLILQYLAAISG---KHSW------IEQQIIEANPIMEAFGNAKTVRNDNSSRFGKYIEIRFTPQGAIQGARIQQYLLEKSRIVFQSRDERNYHIFYCMLAGLSTAERERLKLQ-EQSPSQYHYLAQGGCFTLPGRGDAKDFADIRAAMKVLSFKPEEVWSILSLLAAILHLGNLRFTATEVANLATAEIDDTPNLQRVAQLLGIPISALNAALTQRTIFVHGEHVTTSLSKEAAIEGRDAFVKSLYDGIFVRIVRRINETINKQVDQPMNS----------------IGVLDIFGFENFDNNSFEQLCINYANENLQQFFVGHIFKMEQDEYQNEHINWQHIEFQDNQQILDLIGMKPMNLMSLIDEESKFPKGTDQTLLEKLHVQHGNRSIYVKGKTTQTSLFGIRHYAGVVMYNPLGFLEKNRDSFSGDLRTLVQRSTNKYLVDIF-PHEMPM-------------------------DTAKKQPTLCVKFRNSLDMLMRTLSQAHPYFIRCIKPNEYKEPKNFDKELCVRQLRYSGMMETARIRRAGYPIRHAYRAFVERYRLLVPPVGPLEQCDCRKLARQICEVALPADSDRQYGKTKLFLRDEDDASLELQRSQLMLKSIVTIQRGIRRVLFRRYMKRYREAIITVQRYWRGRLQRRKYQVMRQGFHRLGACIAAQQLTTKFTMVRCRTIKLQALSRGYLVRKDFQK 832
BLAST of Dach-2 vs. Ensembl Zebrafish
Match: myo5b (myosin VB [Source:ZFIN;Acc:ZDB-GENE-031219-7]) HSP 1 Score: 1098.96 bits (2841), Expect = 0.000e+0 Identity = 717/1902 (37.70%), Postives = 1065/1902 (55.99%), Query Frame = 2
Query: 47 MALYEMYSKGVKIWIPDEESVWIGATVLQFHKEKN-VIKIITDNGISKELNLSSKKCA-PFLRNPDILIGQKDLTYLSYLNEPEVLYNLQIRFCERREIYTYCGIVLVAINPYQELSIYGKEIINAYHSQNSVDLDPHIFAVAENAFRRMSSFGENQSIIVSGESGAGKTVSAKYTMRYFALVGGSKTKQSFNLTETQIERKVLLSNPILEAFGNAKTIRNDNSSRFGKYLEILFNPRNQVIGANMCTYLLEKSRVVFQNLGERNYHIFYQIVTHCQSEDELLMNTGLVNNVEMYDYLRYGESLEIDGVDDSHEFLITKNSFLQLGIDLNKFKTICEILAAILHLGNIRF-RFHDATDSSIIENPELLKLIAGLLGCSIDQLKIWLCFRTISTFQETLHKPLSKAEAQYFRDAFVKTLYSNLFDWIVKQANKVLSTDVSINIKKKLKKTIVVNQEDKKKFIAVLDIYGFETFAENSFEQFCINFANEKLQLQFNLHVFKLEQEEYMNEGLEWTFIDYYNNQPCIDLIESRXXXXXXXXXXXXXXXXSDENWCCKIYSHHLNKSANFNKPKLSNMVFIIEHFAGPVEYKCAGFIEKNRDSVLEEQINLLKASDVQLIAELFRDSEIEIFDTNNXXXXXXXXXXXXXXXXXXQENTRKMKKTVGSQFRNSLKSLMDALNKTNPHYVRCIKPNDLKLPFTFCPERAVQQLRACGVLETIRLSAAGFPSRWTYSDFYHRYYILMSNFNVKNHDFKAGSQKIVETLITVPDAFRFGNTKLFFRPGQVALLEKLRGHKIESSVTLIQSILRGSIERKKYLIIHKLTVQIQTYIRRKLAIEKATKLSQIRAVIIIQSFYRMYLARKLFVKMKCAVLAIEKWRRKIITTRLKQAYKKENCVIICQAIVRRFIQRRKFLKIQRGVILIQNHYRRRKAKETLKILKIEARSINHIKFVNKGLENKIIELTQKLDTKEKEMCXXXXXXXXXXXXXXXXXXXXXAESAKIYQNTVQDLQTEIIQLKKELNREIVEKNKIFADKELLEINYKKKINYLENLIEELKSSPSV-----------IEPNIICNGDEAQQSICQDEHQKFINEQMDHQKLVREYEKLEMKYENLYKEFLFVKSSNQKPSINYDNQTSNDSETESTFSKDDADVESLSDKVDAKTTKEHXXXXXXXXXXLPNFISESISTAGDLAVVMQLQMNISSLSQENNRLKETVQQFED------ELLKYEQCAEDSKGLVIHNEYD---------------NELLSIIKDIKGMDEHGLKSRLIDEVANLKKKLKQSNE--DYQK-----LRLHIFDGSMSKLTGNLDHESIN--SEEEELKRAFESQKE----ANRKMLKEIEGIKANNVDLKKALFQIRKDKEQLQVQLGKQHLMIRHGVEYLQNL-----KLTPKERLDKFVQNEISRILLENLKLQERNDQIISETIELKRGLKYFAFRLQKYEGSLVPNPNKEEDLLQLIQNVIYHSKMKTIGKRECYSEIGLIDLNMSELSIFIKSFIFDLSPSICLQYEPYHLVPYIIFMVTRKFDFYKEEDQMTNFLSKLIVALKRTIRKRRNYIEYLVMLLSNVFCLVNLXXXXXXXXXXXXLNTAEDIQHYFVHYDLNEFIRLLKELCVTLFQMILKTIVDNLLPQSLCIDAILVHEAIIDFLSKDGTKYK---SNIETQ---PKNTSFNVLTKNLQSVLEILKNHKIPQLIINQIFVHIAYLINAYCLNTLLFRTDLCYFSKGLQIKYNLSSFETWIRYQKLIDSGALQCLRPMTEAVQLLQTLIDSDEDAKFVCDMCEYLNTRQVVKILNNFNPRDGYGCRLSSGLIAKIETQMKIKRGDEPSESKLETPTVIEIPIDIPFIHNGVSLCRTIIPKPLYLSCLT 5575
M++ E+YSK ++WIPD + VW A +++ +KE + V+ + ++ + E + SK PFLRNPDIL+G+ DLT LSYL+EP VL+NL++RF E IYTYCGIVLVAINPY++L IYG+E+INAY QN D+DPHIFAVAE AF++M+ +NQSIIVSGESGAGKTVSAKY MR+FA VGGS +T +E KVL S+PI+EA GNAKT RNDNSSRFGKY++I F+ R +IGANM TYLLEKSRVVFQ ERNYHIFYQ+ C + + + E + Y GE++ I+GV+D+ + + T+ + LG+ N +I +I+A+ILHLGN+ + D I N L LLG +Q++ WLC R + T ET K + ++A RDA K +Y++LFDWIV+ NK L T + FI VLDIYGFETF NSFEQFCIN+ANEKLQ QFN HVFKLEQEEYM E + WT ID+Y+NQPCIDLIE++LG+LDLLDEECK+ KG+D+NW K+YS H + S +F KP++SN FI+ HFA VEY+C GF+EKNRD+V EEQIN+LKAS QL+A+LF D++ D + + + + + + R+ +KTVG+QFRNSL LM+ LN T PHYVRCIKPND K F F RAVQQLRACGVLETIR+SAAG+PSRWTY DF+ RY +LM+ ++ D K + ++E LI PD F+FG TK+FFR GQVA LEKLR K + IQ +RG ++R +Y I K + +Q Y R LA A L RA +I Q YRM R+ +++++ AV+ I+ + R + RL Q + + +I Q VR ++ R+K+ + + I+IQ YRR +AK LK LKIEARS H K +N G+ENKI++L +K+D + KE+ L K + + E + T Q T++ L++EL + E + A K+LLE + + LE +EEL+ +V I+ + G + Q + +H+ +E+ +Q LV+EY +LE +YENL ++ +K + N S S S + SLS+ D T + V + + A DL+V M+LQ + L QE RL+ + + E+ K +D + +N NEL + D E+ + L D L +LK +NE D +K L+ I + ++ T NL+H + N SE + K ++ A++K+L+ L+ Q R + E L Q+ +++ +E Q++ L+P ++ VQ EI+R+ ENL L+E +++ +LK+ L+ + ++Q+ E + Q ++ ++ T+ +RE E G+++ + ++ +K+ + D+ P+ P L YI+FM R D+ ++ ++ + L+ I A+K+ ++K + E L+N L++ +QYSG + F N+A+ +H ++DL E+ ++L +L + ++Q ++K N+ P + + A+L E+I Y+ S+++ + P + L K L + +H + I Q+ + Y INA LN LL R D+C +S G+Q++YN+S E W+R + L GA+ + P+ +A QLLQ + +DA+ +C +C L+ +Q+VKILN + P + + R++ I I+ +++ D ++L T P+ P+ + +SL IP L L LT
Sbjct: 1 MSVTELYSKYTRVWIPDPDEVWRSAEIIKDYKEGDTVLHLKLEDESTLEYPIGSKDNPLPFLRNPDILVGENDLTALSYLHEPAVLHNLKVRFLESNHIYTYCGIVLVAINPYEQLHIYGEEVINAYSGQNMGDMDPHIFAVAEEAFKQMARDEKNQSIIVSGESGAGKTVSAKYAMRFFATVGGSAN-------DTNVEEKVLASSPIMEAIGNAKTTRNDNSSRFGKYIQIGFDRRYHIIGANMRTYLLEKSRVVFQAEEERNYHIFYQLCASCSLPE---FKDLTLTSAEDFTYTSLGENIFIEGVNDAEDLVKTREALTMLGVKENHQMSIFKIIASILHLGNVEIVQERDGESCHINRNDTHLHHFCRLLGIEQEQMENWLCRRKLVTTSETYVKNMPHSQAVNARDALAKHIYAHLFDWIVEHINKSLHTSTK-----------------QHSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNSHVFKLEQEEYMKEQIPWTLIDFYDNQPCIDLIEAKLGILDLLDEECKVPKGTDQNWAQKLYSKH-SGSGHFEKPRMSNKSFIVVHFADKVEYQCDGFLEKNRDTVYEEQINILKASKFQLVADLFDDAK----DAAPHPGSKTSRINVRPAKPAPKGHNREHRKTVGTQFRNSLHLLMETLNATTPHYVRCIKPNDYKESFVFDSRRAVQQLRACGVLETIRISAAGYPSRWTYPDFFSRYRVLMTKKDLSVGDKKQVCKNLLEILIKDPDKFQFGKTKIFFRAGQVAYLEKLRADKFRFACIKIQKTVRGWLQRIRYRKIRKSAITLQRYGRGYLARRYAEMLRLTRAAVICQKQYRMVQVRREYLRVRRAVITIQAFTRGMFIRRLYQEFLLHHKAMIIQKTVRGWLVRKKYQRSRYAAIVIQCFYRRVRAKRQLKQLKIEARSAEHFKKLNVGMENKIVQLQKKMDNQSKELKSQNENLAVAKTVLETEVSKLSKELETL--RTRQVAGTQMTSLQEELEKLRAELQEAHAHKKLLEEEFSNEKQGLEQRVEELEKENTVLKKEKEEMNRRIQTSTQDQGGDVSQKESRLQHE-LDDERQRYQNLVKEYSRLEQRYENLQEDMSSMKF--------HPGHRRNPSNQSSLGSDSNYPSISLSEVGDTDDTIQQVEEMGIE------------KAAMDLSVFMKLQKRVRELEQERKRLQTNLDKVEELSKRKGSEAKNSTSEDDINADLAYNSLKRQELETENKKLKNDLNELRKAVAD--RASENNSSNELQDGYNLLLSQLKAANEELDVRKEEVLMLKTQIVNS--TRQTENLNHINSNDVSEWTDNKSPVNTEDRVDAPASKKLLE---------TQLQTQTRQHRDELEALHTQIE----LLKDNLEKKQDMLDHFSTLSPDALVEFSVQQEITRLTNENLDLKELVEKLEKNEKKLKKQLRIYMKKVQELE------------VTQATKSRPELTRQFTVQRREKDFE-GMLEYYKEDEALLVKTLVTDMKPNAVSATVPC-LPAYILFMCIRHADYINDDQKVHSLLTATINAIKKVLKKNNDDFEMTSFWLANASRLLHCLKQYSGDEAFMTQNSAKQNEHCLKNFDLAEYRQVLSDLSIQIYQQLVKVAEANMQP--MIVSAMLESESIPSLAGVKPMGYRNRSSSVDCESGGPAGYTLQALIKQLAQFYSTMADHGLDPEISQQVLRQLFYSINAVTLNNLLLRKDVCSWSTGMQLRYNISQLEEWLRGKNLHQCGAVATMEPVIQAAQLLQVKKKTSQDAEAICSLCTALSLQQIVKILNLYTPLNEFEERVTVSFIRDIQNRLQ----DRIENNQLLADTKYTFPVLFPYTPSNLSLETIHIPASLSLDFLT 1810
BLAST of Dach-2 vs. Ensembl Zebrafish
Match: myo5aa (myosin VAa [Source:ZFIN;Acc:ZDB-GENE-041027-2]) HSP 1 Score: 1092.8 bits (2825), Expect = 0.000e+0 Identity = 711/1891 (37.60%), Postives = 1082/1891 (57.22%), Query Frame = 2
Query: 62 MYSKGVKIWIPDEESVWIGATVLQFHKEKN-VIKIITDNGISKELNLSSK-KCAPFLRNPDILIGQKDLTYLSYLNEPEVLYNLQIRFCERREIYTYCGIVLVAINPYQELSIYGKEIINAYHSQNSVDLDPHIFAVAENAFRRMSSFGENQSIIVSGESGAGKTVSAKYTMRYFALVGGSKTKQSFNLTETQIERKVLLSNPILEAFGNAKTIRNDNSSRFGKYLEILFNPRNQVIGANMCTYLLEKSRVVFQNLGERNYHIFYQIVTHCQSEDELLMNTGLVNNVEMYDYLRYGESLEIDGVDDSHEFLITKNSFLQLGIDLNKFKTICEILAAILHLGNIRFRFHDATDSSIIENPELLKLIAGLLGCSIDQLKIWLCFRTISTFQETLHKPLSKAEAQYFRDAFVKTLYSNLFDWIVKQANKVLSTDVSINIKKKLKKTIVVNQEDKKKFIAVLDIYGFETFAENSFEQFCINFANEKLQLQFNLHVFKLEQEEYMNEGLEWTFIDYYNNQPCIDLIESRXXXXXXXXXXXXXXXXSDENWCCKIYSHHLNKSANFNKPKLSNMVFIIEHFAGPVEYKCAGFIEKNRDSVLEEQINLLKASDVQLIAELFRDSEIEIFDTNNXXXXXXXXX-XXXXXXXXXQENTRKMKKTVGSQFRNSLKSLMDALNKTNPHYVRCIKPNDLKLPFTFCPERAVQQLRACGVLETIRLSAAGFPSRWTYSDFYHRYYILMSNFNVKNHDFKAGSQKIVETLITVPDAFRFGNTKLFFRPGQVALLEKLRGHKIESSVTLIQSILRGSIERKKYLIIHKLTVQIQTYIRRKLAIEKATKLSQIRAVIIIQSFYRMYLARKLFVKMKCAVLAIEKWRRKIITTRLKQAYKKENCVIICQAIVRRFIQRRKFLKIQRGVILIQNHYRRRKAKETLKILKIEARSINHIKFVNKGLENKIIELTQKLDTKEKEMCXXXXXXXXXXXXXXXXXXXXXA---------ESAKIYQNTVQDLQTEIIQLKKELNREIVEKNKIFADKELLEINYKKKINYLENLIEELKSSPS----VIEPNIICNGDEAQQSICQDEHQKFIN----EQMDHQKLVREYEKLEMKYENLYKEFLFVKSSNQKPSINYDNQTSNDSETESTFSKDDADVESLSDKVDAKTTKEHXXXXXXXXXXLPNFISESISTA-GDLAVVMQLQMNISSLSQE----NNRLKETVQQFEDELLKYEQCAEDSKGLVIHNE-------------YDNELLSIIKDIKGMDEHGLKSRLIDEVANLKKKLKQSNEDYQ--KLRLHIFDGSMSKLTGNLDHESINSEE----EELKRAFESQKEANRKMLKEIEGIKANNVDLKKAL-FQIRKDKEQLQVQLGKQHLMI----RHGVEYLQNLKLTPKERLDKFVQNEISRILLENLKLQERNDQIISETIELKRGLKYFAFRLQKYEGSLVP-NPNKEEDLLQLIQNVIYHSKMKTIGKRECYSEIGLIDLNMSELSIFIKSFIFDLSP-SICLQYEPYHLVPYIIFMVTRKFDFYKEEDQMTNFLSKLIVALKRTIRKRRNYIEYLVMLLSNVFCLVNLXXXXXXXXXXXXLNTAEDIQHYFVHYDLNEFIRLLKELCVTLFQMILKTIVDNLLPQSLCIDAILVHEAI--IDFLSKDGTKYKSNIETQPKNTSFNVLTKNLQSVLEILKNHKIPQLIINQIFVHIAYLINAYCLNTLLFRTDLCYFSKGLQIKYNLSSFETWIRYQKLIDSGALQCLRPMTEAVQLLQTLIDSDEDAKFVCDMCEYLNTRQVVKILNNFNPRDGYGCRLSSGLIAKIETQMKIKRGDEPSESKLETPTVIEIPIDIPFIHNGVSLCRTIIPKPLYLSCLT 5575
M+ K ++WIPD+E VW A + + +++ + V+++ ++G E L K P LRNPDIL+G+ DLT LSYL+EP VL+NL++RF + + IYTYCGIVLVAINPY+ L IYG +IINAY QN D+DPHIFAVAE A+++M+ NQSIIVSGESGAGKTVSAKY MRYFA V GS +E +E KVL SNPI+E+ GNAKT RNDNSSRFGKY+EI F+ + +IGANM TYLLEKSRVVFQ ERNYHIFYQ+ + + G N+ + Y + G + IDGVDD+ E T+N+F+ LGI+ + + +ILA+ILHLGN+ + D+ S I N L + L+G + + WLC + + T ET KP+ K +A RDA K +Y+ LF+WIV NK L + V + FI VLDIYGFETF NSFEQFCIN+ANEKLQ QFN+HVFKLEQEEYM E + WT ID+Y+NQPCI+LIE+++G+LDLLDEECK+ KGSD++W K+Y+ HL A F KP++SN FII+HFA VEY+C GF+EKN+D+V EEQIN+LKAS L+ ELF D E T + S K + +++ KKTVG QFRNSL+ LM+ LN T PHYVRCIKPND K FTF P+RAVQQLRACGVLETIR+SAAGFPSRWTY +F+ RY +LM +V D K + ++E L+ PD ++FG TK+FFR GQVA LEKLR K+ ++ IQ +R + RKKYL + IQ ++R A A L + RA IIIQ + RMY+ + + + + A LA++ R + +L +A +E+ +I Q +VR ++ R+ F + + ++ +Q RR +AK LK LKIEARS+ H K +N G+ENKI++L +++D + KE + +L + + + +A E AK N V L E+ +L+K+L EK I + + +K I+ L+ + LK+ + +I+ D+ Q+++ ++E Q+ N E+ +Q L+ E+ +LE KY++L KE + + + KP + T + +E+E T++ + A+ E S + E +S + D+++ ++LQ +S L QE N L +QF+ + ++ + ++G + E ++L + + ++G E G + L +L SNE+ + K + I + + H++ +E E++++ ++++ + M G+K N L+ L Q R +++V G+ H + R QNL+L P+ R++ +Q+EI+R+ ENL L E+ ++ +LK+ LK FA ++ EG + +P + D + + V I +RE + G+++ + +K+ I +L P + + P L YI+FM R D+ ++ ++ + L+ +I ++K+ ++KR + E + L+N ++ +QYSG +QF N+ + +H ++DL E+ ++L +L + ++Q ++K + +N+L Q + + +L HE I + + G + +++ + + + + L + I+ +H +I Q+ Y+I A LN LL R D+C +SKG+QI+YN+S E W+R + L+ GA + L P+ +A QLLQ +DEDA+ +C MC L+T Q+VK+LN + P + + R+S I I+T+++ D +L T + P+ PF + ++L IP L L+ LT
Sbjct: 8 MFIKYARVWIPDDEEVWRSAELTKDYRQGDGVLQLQLEDGKDLEFKLDPKTNNLPHLRNPDILVGENDLTALSYLHEPAVLHNLKVRFIDSKLIYTYCGIVLVAINPYETLPIYGADIINAYSGQNMGDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYFATVSGSA-------SEANVEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKKYHIIGANMRTYLLEKSRVVFQADEERNYHIFYQLCASAHLPEFKALKLGKAND---FHYTKQGRNPVIDGVDDAKEMSTTRNAFILLGINESYQMGLFQILASILHLGNVDVKDRDSDSSIIPPNNGHLSVFCELMGVTYQDMSHWLCHKKLKTATETYIKPIPKLQAINARDALAKHIYAKLFNWIVDHVNKALHSTVK-----------------QHSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKEQIPWTLIDFYDNQPCINLIEAKMGILDLLDEECKMPKGSDDSWAQKLYNTHLKTCALFEKPRMSNKAFIIQHFADKVEYQCDGFLEKNKDTVNEEQINVLKASKFDLLVELFHDEEKATSPTGAAPGPGGRTRLSVKPDKGKSSQASKEHKKTVGLQFRNSLQLLMETLNATTPHYVRCIKPNDYKHAFTFDPKRAVQQLRACGVLETIRISAAGFPSRWTYQEFFSRYRVLMKQKDVLT-DKKMTCKNVLEKLVQDPDKYQFGKTKIFFRAGQVAYLEKLRADKLRAACIRIQKTIRCWLARKKYLRMKHAATTIQRFVRGYQARCLAKFLRRTRAAIIIQKYQRMYIQKTCYKRKQAAALAMQCILRAYMARQLYKALLREHKAVIIQKMVRGWLARQWFKRSLKAIVYLQCCIRRMRAKRELKKLKIEARSVEHFKKLNIGMENKIMQLQRRIDDQNKENRSMSERLNTLETSHAVESERMRAEVTRLRGAEEDAKNNANKVTSLLEELERLRKDLQNTQKEKKAIEDWAQTYQDEMEKMISELKEQNQLLKTEKNNLNQLIQEQSQQWTDKMQRAL-KEETQQLENDLNEERSRYQNLLTEHLRLEEKYDDL-KEEITLAVNVPKPGHRRTDSTHSSNESECTYNSEFAESEEGSR------------------------VGEDVSKSILDMSLFLKLQKRVSELEQEKQSLQNELDRREEQFQRARARDDEEHKKARGAELEYESLKRQELESENKKLKHDLNQMRQSLRGSVEAGSGAPGSPAYTVLLDQLNASNEELEVRKEEVLILRSQLVSQKEAMQHKTTMTEPLPYIEDVQKLTDAKEISQAYM-----GLKDTNRLLESQLQAQRRSHDNEVEVLRGELHSLKEENNRQQQLLAQNLQLPPEARIEASLQHEITRLTNENLDLMEQLEKQDKTVRKLKKQLKVFAKKINDLEGGQMDVSPGQTAD--EPVHPV-------NIPRREKDFQ-GMLEYKKEDELKLVKNIILELKPRGVAVNLIP-GLPAYILFMCLRHADYINDDQKVRSLLTSVINSIKKILKKRGDDFETVSFWLANTCRFLHCLKQYSGDEQFMKHNSPKQNEHCLSNFDLAEYRQVLSDLAIQIYQQLIKCM-ENIL-QPMIVSGMLEHETIQGVSGVKPTGLRKRTSSIADEGTYTLDSIIRQLNTFHSIMCHHGTDPELIKQVVKQQFYIIGAVTLNNLLLRKDMCSWSKGMQIRYNVSQLEEWLRDKNLMTCGAKETLEPLIQAAQLLQVKKKTDEDAEAICSMCNALSTAQIVKVLNLYTPVNAFEERVSVLFIRTIQTRLR----DRKESPQLLMDTKLIYPVTFPFNPSSLALETIQIPSSLNLAFLT 1822
BLAST of Dach-2 vs. Ensembl Zebrafish
Match: myo5aa (myosin VAa [Source:ZFIN;Acc:ZDB-GENE-041027-2]) HSP 1 Score: 1090.1 bits (2818), Expect = 0.000e+0 Identity = 715/1921 (37.22%), Postives = 1088/1921 (56.64%), Query Frame = 2
Query: 47 MALYEMYSKGVKIWIPDEESVWIGATVLQFHKEKN-VIKIITDNGISKELNLSSK-KCAPFLRNPDILIGQKDLTYLSYLNEPEVLYNLQIRFCERREIYTYCGIVLVAINPYQELSIYGKEIINAYHSQNSVDLDPHIFAVAENAFRRMSSFGENQSIIVSGESGAGKTVSAKYTMRYFALVGGSKTKQSFNLTETQIERKVLLSNPILEAFGNAKTIRNDNSSRFGKYLEILFNPRNQVIGANMCTYLLEKSRVVFQNLGERNYHIFYQIVTHCQSEDELLMNTGLVNNVEMYDYLRYGESLEIDGVDDSHEFLITKNSFLQLGIDLNKFKTICEILAAILHLGNIRFRFHDATDSSIIENPELLKLIAGLLGCSIDQLKIWLCFRTISTFQETLHKPLSKAEAQYFRDAFVKTLYSNLFDWIVKQANKVLSTDVSINIKKKLKKTIVVNQEDKKKFIAVLDIYGFETFAENSFEQFCINFANEKLQLQFNLHVFKLEQEEYMNEGLEWTFIDYYNNQPCIDLIESRXXXXXXXXXXXXXXXXSDENWCCKIYSHHLNKSANFNKPKLSNMVFIIEHFAGPVEYKCAGFIEKNRDSVLEEQINLLKASDVQLIAELFRDSEIEIFDTNNXXXXXXXXX-XXXXXXXXXQENTRKMKKTVGSQFRNSLKSLMDALNKTNPHYVRCIKPNDLKLPFTFCPERAVQQLRACGVLETIRLSAAGFPSRWTYSDFYHRYYILMSNFNVKNHDFKAGSQKIVETLITVPDAFRFGNTKLFFRPGQVALLEKLRGHKIESSVTLIQSILRGSIERKKYLIIHKLTVQIQTYIRRKLAIEKATKLSQIRAVIIIQSFYRMYLARKLFVKMKCAVLAIEKWRRKIITTRLKQAYKKENCVIICQAIVRRFIQRRKFLKIQRGVILIQNHYRRRKAKETLKILKIEARSINHIKFVNKGLENKIIELTQKLDTKEKEMCXXXXXXXXXXXXXXXXXXXXXA---------ESAKIYQNTVQDLQTEIIQLKKELNREIVEKNKIFADKELLEINYKKKINYLENLIEELKSSPS----VIEPNIICNGDEAQQSICQDEHQKFIN----EQMDHQKLVREYEKLEMKYENLYKEFLFVKSSNQKPSINYDNQTSNDSETESTFSKDDADVESLSDKVDAKTTKEHXXXXXXXXXXLPNFISESISTA-GDLAVVMQLQMNISSLSQE----NNRLKETVQQFEDELLKYEQCAEDSKGLVIHNE-------------YDNELLSIIKDIKGMDEHGLKSRLIDEVANLKKKLKQSNEDYQ--KLRLHIFDGSMSKLTGNLDHESINSEE----EELKRAFESQKEANRKMLKEIEGIKANNVDLKKAL-FQIRKDKEQLQVQLGKQHLMI----RHGVEYLQNLKLTPKERLDKFVQNEISRILLENLKLQ-------------------------ERNDQIISETIELKRGLKYFAFRLQKYEGSLVP-NPNKEEDLLQLIQNVIYHSKMKTIGKRECYSEIGLIDLNMSELSIFIKSFIFDLSP-SICLQYEPYHLVPYIIFMVTRKFDFYKEEDQMTNFLSKLIVALKRTIRKRRNYIEYLVMLLSNVFCLVNLXXXXXXXXXXXXLNTAEDIQHYFVHYDLNEFIRLLKELCVTLFQMILKTIVDNLLPQSLCIDAILVHEAI--IDFLSKDGTKYKSNIETQPKNTSFNVLTKNLQSVLEILKNHKIPQLIINQIFVHIAYLINAYCLNTLLFRTDLCYFSKGLQIKYNLSSFETWIRYQKLIDSGALQCLRPMTEAVQLLQTLIDSDEDAKFVCDMCEYLNTRQVVKILNNFNPRDGYGCRLSSGLIAKIETQMKIKRGDEPSESKLETPTVIEIPIDIPFIHNGVSLCRTIIPKPLYLSCLT 5575
MA E+Y+K ++WIPD+E VW A + + +++ + V+++ ++G E L K P LRNPDIL+G+ DLT LSYL+EP VL+NL++RF + + IYTYCGIVLVAINPY+ L IYG +IINAY QN D+DPHIFAVAE A+++M+ NQSIIVSGESGAGKTVSAKY MRYFA V GS +E +E KVL SNPI+E+ GNAKT RNDNSSRFGKY+EI F+ + +IGANM TYLLEKSRVVFQ ERNYHIFYQ+ + + G N+ + Y + G + IDGVDD+ E T+N+F+ LGI+ + + +ILA+ILHLGN+ + D+ S I N L + L+G + + WLC + + T ET KP+ K +A RDA K +Y+ LF+WIV NK L + V + FI VLDIYGFETF NSFEQFCIN+ANEKLQ QFN+HVFKLEQEEYM E + WT ID+Y+NQPCI+LIE+++G+LDLLDEECK+ KGSD++W K+Y+ HL A F KP++SN FII+HFA VEY+C GF+EKN+D+V EEQIN+LKAS L+ ELF D E T + S K + +++ KKTVG QFRNSL+ LM+ LN T PHYVRCIKPND K FTF P+RAVQQLRACGVLETIR+SAAGFPSRWTY +F+ RY +LM +V D K + ++E L+ PD ++FG TK+FFR GQVA LEKLR K+ ++ IQ +R + RKKYL + IQ ++R A A L + RA IIIQ + RMY+ + + + + A LA++ R + +L +A +E+ +I Q +VR ++ R+ F + + ++ +Q RR +AK LK LKIEARS+ H K +N G+ENKI++L +++D + KE + +L + + + +A E AK N V L E+ +L+K+L EK I + + +K I+ L+ + LK+ + +I+ D+ Q+++ ++E Q+ N E+ +Q L+ E+ +LE KY++L KE + + + KP + T + +E+E T++ + A+ E S + E +S + D+++ ++LQ +S L QE N L +QF+ + ++ + ++G + E ++L + + ++G E G + L +L SNE+ + K + I + + H++ +E E++++ ++++ + M G+K N L+ L Q R +++V G+ H + R QNL+L P+ R++ +Q+EI+R+ ENL+L E+ D+ + +LK+ LK FA ++ EG + +P + D + + V I +RE + G+++ + +K+ I +L P + + P L YI+FM R D+ ++ ++ + L+ +I ++K+ ++KR + E + L+N ++ +QYSG +QF N+ + +H ++DL E+ ++L +L + ++Q ++K + +N+L Q + + +L HE I + + G + +++ + + + + L + I+ +H +I Q+ Y+I A LN LL R D+C +SKG+QI+YN+S E W+R + L+ GA + L P+ +A QLLQ +DEDA+ +C MC L+T Q+VK+LN + P + + R+S I I+T+++ D +L T + P+ PF + ++L IP L L+ LT
Sbjct: 1 MAASELYTKYARVWIPDDEEVWRSAELTKDYRQGDGVLQLQLEDGKDLEFKLDPKTNNLPHLRNPDILVGENDLTALSYLHEPAVLHNLKVRFIDSKLIYTYCGIVLVAINPYETLPIYGADIINAYSGQNMGDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYFATVSGSA-------SEANVEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKKYHIIGANMRTYLLEKSRVVFQADEERNYHIFYQLCASAHLPEFKALKLGKAND---FHYTKQGRNPVIDGVDDAKEMSTTRNAFILLGINESYQMGLFQILASILHLGNVDVKDRDSDSSIIPPNNGHLSVFCELMGVTYQDMSHWLCHKKLKTATETYIKPIPKLQAINARDALAKHIYAKLFNWIVDHVNKALHSTVK-----------------QHSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKEQIPWTLIDFYDNQPCINLIEAKMGILDLLDEECKMPKGSDDSWAQKLYNTHLKTCALFEKPRMSNKAFIIQHFADKVEYQCDGFLEKNKDTVNEEQINVLKASKFDLLVELFHDEEKATSPTGAAPGPGGRTRLSVKPDKGKSSQASKEHKKTVGLQFRNSLQLLMETLNATTPHYVRCIKPNDYKHAFTFDPKRAVQQLRACGVLETIRISAAGFPSRWTYQEFFSRYRVLMKQKDVLT-DKKMTCKNVLEKLVQDPDKYQFGKTKIFFRAGQVAYLEKLRADKLRAACIRIQKTIRCWLARKKYLRMKHAATTIQRFVRGYQARCLAKFLRRTRAAIIIQKYQRMYIQKTCYKRKQAAALAMQCILRAYMARQLYKALLREHKAVIIQKMVRGWLARQWFKRSLKAIVYLQCCIRRMRAKRELKKLKIEARSVEHFKKLNIGMENKIMQLQRRIDDQNKENRSMSERLNTLETSHAVESERMRAEVTRLRGAEEDAKNNANKVTSLLEELERLRKDLQNTQKEKKAIEDWAQTYQDEMEKMISELKEQNQLLKTEKNNLNQLIQEQSQQWTDKMQRAL-KEETQQLENDLNEERSRYQNLLTEHLRLEEKYDDL-KEEITLAVNVPKPGHRRTDSTHSSNESECTYNSEFAESEEGSR------------------------VGEDVSKSILDMSLFLKLQKRVSELEQEKQSLQNELDRREEQFQRARARDDEEHKKARGAELEYESLKRQELESENKKLKHDLNQMRQSLRGSVEAGSGAPGSPAYTVLLDQLNASNEELEVRKEEVLILRSQLVSQKEAMQHKTTMTEPLPYIEDVQKLTDAKEISQAYM-----GLKDTNRLLESQLQAQRRSHDNEVEVLRGELHSLKEENNRQQQLLAQNLQLPPEARIEASLQHEITRLTNENLELHSDDPKEYKAYRISMLRRMVDLMEQLEKQDKTVR---KLKKQLKVFAKKINDLEGGQMDVSPGQTAD--EPVHPV-------NIPRREKDFQ-GMLEYKKEDELKLVKNIILELKPRGVAVNLIP-GLPAYILFMCLRHADYINDDQKVRSLLTSVINSIKKILKKRGDDFETVSFWLANTCRFLHCLKQYSGDEQFMKHNSPKQNEHCLSNFDLAEYRQVLSDLAIQIYQQLIKCM-ENIL-QPMIVSGMLEHETIQGVSGVKPTGLRKRTSSIADEGTYTLDSIIRQLNTFHSIMCHHGTDPELIKQVVKQQFYIIGAVTLNNLLLRKDMCSWSKGMQIRYNVSQLEEWLRDKNLMTCGAKETLEPLIQAAQLLQVKKKTDEDAEAICSMCNALSTAQIVKVLNLYTPVNAFEERVSVLFIRTIQTRLR----DRKESPQLLMDTKLIYPVTFPFNPSSLALETIQIPSSLNLAFLT 1842
BLAST of Dach-2 vs. Ensembl Zebrafish
Match: myo5b (myosin VB [Source:ZFIN;Acc:ZDB-GENE-031219-7]) HSP 1 Score: 1089.33 bits (2816), Expect = 0.000e+0 Identity = 719/1918 (37.49%), Postives = 1066/1918 (55.58%), Query Frame = 2
Query: 47 MALYEMYSKGVKIWIPDEESVWIGATVLQFHKEKN-VIKIITDNGISKELNLSSKKCA-PFLRNPDILIGQKDLTYLSYLNEPEVLYNLQIRFCERREIYTYCGIVLVAINPYQELSIYGKEIINAYHSQNSVDLDPHIFAVAENAFRRMSSFGENQSIIVSGESGAGKTVSAKYTMRYFALVGGSKTKQSFNLTETQIERKVLLSNPILEAFGNAKTIRNDNSSRFGKYLEILFNPRNQVIGANMCTYLLEKSRVVFQNLGERNYHIFYQIVTHCQSEDELLMNTGLVNNVEMYDYLRYGESLEIDGVDDSHEFLITKNSFLQLGIDLNKFKTICEILAAILHLGNIRF-RFHDATDSSIIENPELLKLIAGLLGCSIDQLKIWLCFRTISTFQETLHKPLSKAEAQYFRDAFVKTLYSNLFDWIVKQANKVLSTDVSINIKKKLKKTIVVNQEDKKKFIAVLDIYGFETFAENSFEQFCINFANEKLQLQFNLHVFKLEQEEYMNEGLEWTFIDYYNNQPCIDLIESRXXXXXXXXXXXXXXXXSDENWCCKIYSHHLNKSANFNKPKLSNMVFIIEHFAGPVEYKCAGFIEKNRDSVLEEQINLLKASDVQLIAELFRDSEIEIFDTNNXXXXXXXXXXXXXXXXXXQENTRKMKKTVGSQFRNSLKSLMDALNKTNPHYVRCIKPNDLKLPFTFCPERAVQQLRACGVLETIRLSAAGFPSRWTYSDFYHRYYILMSNFNVKNHDFKAGSQKIVETLITVPDAFRFGNTKLFFRPGQVALLEKLRGHKIESSVTLIQSILRGSIERKKYLIIHKLTVQIQTYIRRKLAIEKATKLSQIRAVIIIQSFYRMYLARKLFVKMKCAVLAIEKWRRKIITTRLKQAYKKENCVIICQAIVRRFIQRRKFLKIQRGVILIQNHYRRRKAKETLKILKIEARSINHIKFVNKGLENKIIELTQKLDTKEKEMCXXXXXXXXXXXXXXXXXXXXXAESAKIYQNTVQDLQTEIIQLKKELNREIVEKNKIFADKELLEINYKKKINYLENLIEELKSSPSV-----------IEPNIICNGDEAQQSICQDEHQKFINEQMDHQKLVREYEKLEMKYENLYKEFLFVKSSNQKPSINYDNQTSNDSETESTFSKDDADVESLSDKVDAKTTKEHXXXXXXXXXXLPNFISESISTAGDLAVVMQLQMNISSLSQENNRLKETVQQFED------ELLKYEQCAEDSKGLVIHNEYD---------------NELLSIIKDIKGMDEHGLKSRLIDEVANLKKKLKQSNE--DYQK-----LRLHIFDGSMSKLTGNLDHESINSE--------------EEELKRAFESQKEANRKMLKE-------IEGIKANNVDLKKAL-FQIRKDKEQLQVQLGKQHLMIRHGVEYLQNL-----KLTPKERLDKFVQNEISRILLENLKLQERNDQIISETIELKRGLKYFAFRLQKYEGSLVPNPNKEEDLLQLIQNVIYHSKMKTIGKRECYSEIGLIDLNMSELSIFIKSFIFDLSPSICLQYEPYHLVPYIIFMVTRKFDFYKEEDQMTNFLSKLIVALKRTIRKRRNYIEYLVMLLSNVFCLVNLXXXXXXXXXXXXLNTAEDIQHYFVHYDLNEFIRLLKELCVTLFQMILKTIVDNLLPQSLCIDAILVHEAIIDFLSKDGTKYK---SNIETQ---PKNTSFNVLTKNLQSVLEILKNHKIPQLIINQIFVHIAYLINAYCLNTLLFRTDLCYFSKGLQIKYNLSSFETWIRYQKLIDSGALQCLRPMTEAVQLLQTLIDSDEDAKFVCDMCEYLNTRQVVKILNNFNPRDGYGCRLSSGLIAKIETQMKIKRGDEPSESKLETPTVIEIPIDIPFIHNGVSLCRTIIPKPLYLSCLT 5575
M +E+Y K ++WIPD + VW A +++ +KE + V+ + ++ + E + SK PFLRNPDIL+G+ DLT LSYL+EP VL+NL++RF E IYTYCGIVLVAINPY++L IYG+E+INAY QN D+DPHIFAVAE AF++M+ +NQSIIVSGESGAGKTVSAKY MR+FA VGGS +T +E KVL S+PI+EA GNAKT RNDNSSRFGKY++I F+ R +IGANM TYLLEKSRVVFQ ERNYHIFYQ+ C + + + E + Y GE++ I+GV+D+ + + T+ + LG+ N +I +I+A+ILHLGN+ + D I N L LLG +Q++ WLC R + T ET K + ++A RDA K +Y++LFDWIV+ NK L T + FI VLDIYGFETF NSFEQFCIN+ANEKLQ QFN HVFKLEQEEYM E + WT ID+Y+NQPCIDLIE++LG+LDLLDEECK+ KG+D+NW K+YS H + S +F KP++SN FI+ HFA VEY+C GF+EKNRD+V EEQIN+LKAS QL+A+LF D++ D + + + + + + R+ +KTVG+QFRNSL LM+ LN T PHYVRCIKPND K F F RAVQQLRACGVLETIR+SAAG+PSRWTY DF+ RY +LM+ ++ D K + ++E LI PD F+FG TK+FFR GQVA LEKLR K + IQ +RG ++R +Y I K + +Q Y R LA A L RA +I Q YRM R+ +++++ AV+ I+ + R + RL Q + + +I Q VR ++ R+K+ + + I+IQ YRR +AK LK LKIEARS H K +N G+ENKI++L +K+D + KE+ L K + + E + T Q T++ L++EL + E + A K+LLE + + LE +EEL+ +V I+ + G + Q + +H+ +E+ +Q LV+EY +LE +YENL ++ +K + N S S S + SLS+ D T + V + + A DL+V M+LQ + L QE RL+ + + E+ K +D + +N NEL + D E+ + L D L +LK +NE D +K L+ I + ++ T NL+H INS E+ + K + L E +G+K L+ L Q R+ +++L+ L Q +++ +E Q++ L+P ++ VQ EI+R+ ENL L+E +++ +LK+ L+ + ++Q+ E + Q ++ ++ T+ +RE E G+++ + ++ +K+ + D+ P+ P L YI+FM R D+ ++ ++ + L+ I A+K+ ++K + E L+N L++ +QYSG + F N+A+ +H ++DL E+ ++L +L + ++Q ++K N+ P + + A+L E+I Y+ S+++ + P + L K L + +H + I Q+ + Y INA LN LL R D+C +S G+Q++YN+S E W+R + L GA+ + P+ +A QLLQ + +DA+ +C +C L+ +Q+VKILN + P + + R++ I I+ +++ D ++L T P+ P+ + +SL IP L L LT
Sbjct: 1 MREHELYVKYTRVWIPDPDEVWRSAEIIKDYKEGDTVLHLKLEDESTLEYPIGSKDNPLPFLRNPDILVGENDLTALSYLHEPAVLHNLKVRFLESNHIYTYCGIVLVAINPYEQLHIYGEEVINAYSGQNMGDMDPHIFAVAEEAFKQMARDEKNQSIIVSGESGAGKTVSAKYAMRFFATVGGSAN-------DTNVEEKVLASSPIMEAIGNAKTTRNDNSSRFGKYIQIGFDRRYHIIGANMRTYLLEKSRVVFQAEEERNYHIFYQLCASCSLPE---FKDLTLTSAEDFTYTSLGENIFIEGVNDAEDLVKTREALTMLGVKENHQMSIFKIIASILHLGNVEIVQERDGESCHINRNDTHLHHFCRLLGIEQEQMENWLCRRKLVTTSETYVKNMPHSQAVNARDALAKHIYAHLFDWIVEHINKSLHTSTK-----------------QHSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNSHVFKLEQEEYMKEQIPWTLIDFYDNQPCIDLIEAKLGILDLLDEECKVPKGTDQNWAQKLYSKH-SGSGHFEKPRMSNKSFIVVHFADKVEYQCDGFLEKNRDTVYEEQINILKASKFQLVADLFDDAK----DAAPHPGSKTSRINVRPAKPAPKGHNREHRKTVGTQFRNSLHLLMETLNATTPHYVRCIKPNDYKESFVFDSRRAVQQLRACGVLETIRISAAGYPSRWTYPDFFSRYRVLMTKKDLSVGDKKQVCKNLLEILIKDPDKFQFGKTKIFFRAGQVAYLEKLRADKFRFACIKIQKTVRGWLQRIRYRKIRKSAITLQRYGRGYLARRYAEMLRLTRAAVICQKQYRMVQVRREYLRVRRAVITIQAFTRGMFIRRLYQEFLLHHKAMIIQKTVRGWLVRKKYQRSRYAAIVIQCFYRRVRAKRQLKQLKIEARSAEHFKKLNVGMENKIVQLQKKMDNQSKELKSQNENLAVAKTVLETEVSKLSKELETL--RTRQVAGTQMTSLQEELEKLRAELQEAHAHKKLLEEEFSNEKQGLEQRVEELEKENTVLKKEKEEMNRRIQTSTQDQGGDVSQKESRLQHE-LDDERQRYQNLVKEYSRLEQRYENLQEDMSSMKF--------HPGHRRNPSNQSSLGSDSNYPSISLSEVGDTDDTIQQVEEMGIE------------KAAMDLSVFMKLQKRVRELEQERKRLQTNLDKVEELSKRKGSEAKNSTSEDDINADLAYNSLKRQELETENKKLKNDLNELRKAVAD--RASENNSSNELQDGYNLLLSQLKAANEELDVRKEEVLMLKTQIVNS--TRQTENLNH--INSNDVSEWTDNKSPVNTEDRVDAPASKNKAQDWGYLNEDGELGLAYQGLKQVARLLETQLQTQTRQHRDELEA-LHTQIELLKDNLEKKQDMLDHFSTLSPDALVEFSVQQEITRLTNENLDLKELVEKLEKNEKKLKKQLRIYMKKVQELE------------VTQATKSRPELTRQFTVQRREKDFE-GMLEYYKEDEALLVKTLVTDMKPNAVSATVPC-LPAYILFMCIRHADYINDDQKVHSLLTATINAIKKVLKKNNDDFEMTSFWLANASRLLHCLKQYSGDEAFMTQNSAKQNEHCLKNFDLAEYRQVLSDLSIQIYQQLVKVAEANMQP--MIVSAMLESESIPSLAGVKPMGYRNRSSSVDCESGGPAGYTLQALIKQLAQFYSTMADHGLDPEISQQVLRQLFYSINAVTLNNLLLRKDVCSWSTGMQLRYNISQLEEWLRGKNLHQCGAVATMEPVIQAAQLLQVKKKTSQDAEAICSLCTALSLQQIVKILNLYTPLNEFEERVTVSFIRDIQNRLQ----DRIENNQLLADTKYTFPVLFPYTPSNLSLETIHIPASLSLDFLT 1836
BLAST of Dach-2 vs. Ensembl Zebrafish
Match: myo5b (myosin VB [Source:ZFIN;Acc:ZDB-GENE-031219-7]) HSP 1 Score: 1089.33 bits (2816), Expect = 0.000e+0 Identity = 717/1929 (37.17%), Postives = 1064/1929 (55.16%), Query Frame = 2
Query: 47 MALYEMYSKGVKIWIPDEESVWIGATVLQFHKEKN-VIKIITDNGISKELNLSSKKCA-PFLRNPDILIGQKDLTYLSYLNEPEVLYNLQIRFCERREIYTYCGIVLVAINPYQELSIYGKEIINAYHSQNSVDLDPHIFAVAENAFRRMSSFGENQSIIVSGESGAGKTVSAKYTMRYFALVGGSKTKQSFNLTETQIERKVLLSNPILEAFGNAKTIRNDNSSRFGKYLEILFNPRNQVIGANMCTYLLEKSRVVFQNLGERNYHIFYQIVTHCQSEDELLMNTGLVNNVEMYDYLRYGESLEIDGVDDSHEFLITKNSFLQLGIDLNKFKTICEILAAILHLGNIRF-RFHDATDSSIIENPELLKLIAGLLGCSIDQLKIWLCFRTISTFQETLHKPLSKAEAQYFRDAFVKTLYSNLFDWIVKQANKVLSTDVSINIKKKLKKTIVVNQEDKKKFIAVLDIYGFETFAENSFEQFCINFANEKLQLQFNLHVFKLEQEEYMNEGLEWTFIDYYNNQPCIDLIESRXXXXXXXXXXXXXXXXSDENWCCKIYSHHLNKSANFNKPKLSNMVFIIEHFAGPVEYKCAGFIEKNRDSVLEEQINLLKASDVQLIAELFRDSEIEIFDTNNXXXXXXXXXXXXXXXXXXQENTRKMKKTVGSQFRNSLKSLMDALNKTNPHYVRCIKPNDLKLPFTFCPERAVQQLRACGVLETIRLSAAGFPSRWTYSDFYHRYYILMSNFNVKNHDFKAGSQKIVETLITVPDAFRFGNTKLFFRPGQVALLEKLRGHKIESSVTLIQSILRGSIERKKYLIIHKLTVQIQTYIRRKLAIEKATKLSQIRAVIIIQSFYRMYLARKLFVKMKCAVLAIEKWRRKIITTRLKQAYKKENCVIICQAIVRRFIQRRKFLKIQRGVILIQNHYRRRKAKETLKILKIEARSINHIKFVNKGLENKIIELTQKLDTKEKEMCXXXXXXXXXXXXXXXXXXXXXAESAKIYQNTVQDLQTEIIQLKKELNREIVEKNKIFADKELLEINYKKKINYLENLIEELKSSPSV-----------IEPNIICNGDEAQQSICQDEHQKFINEQMDHQKLVREYEKLEMKYENLYKEFLFVKSSNQKPSINYDNQTSNDSETESTFSKDDADVESLSDKVDAKTTKEHXXXXXXXXXXLPNFISESISTAGDLAVVMQLQMNISSLSQENNRLKETVQQFED------ELLKYEQCAEDSKGLVIHNEYD---------------NELLSIIKDIKGMDEHGLKSRLIDEVANLKKKLKQSNE--DYQK-----LRLHIFDGSMSKLTGNLDH-------------ESINSEEE--------------------ELKRAFESQKEANRKMLKEIEGIKANNVDLKKALFQIRKDKEQLQVQLGKQHLMIRHGVEYLQNL-----KLTPKERLDKFVQNEISRILLENLKLQERNDQIISETIELKRGLKYFAFRLQKYEGSLVPNPNKEEDLLQLIQNVIYHSKMKTIGKRECYSEIGLIDLNMSELSIFIKSFIFDLSPSICLQYEPYHLVPYIIFMVTRKFDFYKEEDQMTNFLSKLIVALKRTIRKRRNYIEYLVMLLSNVFCLVNLXXXXXXXXXXXXLNTAEDIQHYFVHYDLNEFIRLLKELCVTLFQMILKTIVDNLLPQSLCIDAILVHEAIIDFLSKDGTKYK---SNIETQ---PKNTSFNVLTKNLQSVLEILKNHKIPQLIINQIFVHIAYLINAYCLNTLLFRTDLCYFSKGLQIKYNLSSFETWIRYQKLIDSGALQCLRPMTEAVQLLQTLIDSDEDAKFVCDMCEYLNTRQVVKILNNFNPRDGYGCRLSSGLIAKIETQMKIKRGDEPSESKLETPTVIEIPIDIPFIHNGVSLCRTIIPKPLYLSCLT 5575
M +E+Y K ++WIPD + VW A +++ +KE + V+ + ++ + E + SK PFLRNPDIL+G+ DLT LSYL+EP VL+NL++RF E IYTYCGIVLVAINPY++L IYG+E+INAY QN D+DPHIFAVAE AF++M+ +NQSIIVSGESGAGKTVSAKY MR+FA VGGS +T +E KVL S+PI+EA GNAKT RNDNSSRFGKY++I F+ R +IGANM TYLLEKSRVVFQ ERNYHIFYQ+ C + + + E + Y GE++ I+GV+D+ + + T+ + LG+ N +I +I+A+ILHLGN+ + D I N L LLG +Q++ WLC R + T ET K + ++A RDA K +Y++LFDWIV+ NK L T + FI VLDIYGFETF NSFEQFCIN+ANEKLQ QFN HVFKLEQEEYM E + WT ID+Y+NQPCIDLIE++LG+LDLLDEECK+ KG+D+NW K+YS H + S +F KP++SN FI+ HFA VEY+C GF+EKNRD+V EEQIN+LKAS QL+A+LF D++ D + + + + + + R+ +KTVG+QFRNSL LM+ LN T PHYVRCIKPND K F F RAVQQLRACGVLETIR+SAAG+PSRWTY DF+ RY +LM+ ++ D K + ++E LI PD F+FG TK+FFR GQVA LEKLR K + IQ +RG ++R +Y I K + +Q Y R LA A L RA +I Q YRM R+ +++++ AV+ I+ + R + RL Q + + +I Q VR ++ R+K+ + + I+IQ YRR +AK LK LKIEARS H K +N G+ENKI++L +K+D + KE+ L K + + E + T Q T++ L++EL + E + A K+LLE + + LE +EEL+ +V I+ + G + Q + +H+ +E+ +Q LV+EY +LE +YENL ++ +K + N S S S + SLS+ D T + V + + A DL+V M+LQ + L QE RL+ + + E+ K +D + +N NEL + D E+ + L D L +LK +NE D +K L+ I + ++ T NL+H +N+E+ EL A++ K+ R +L+ L+ Q R + E L Q+ +++ +E Q++ L+P ++ VQ EI+R+ ENL L+E +++ +LK+ L+ + ++Q+ E + Q ++ ++ T+ +RE E G+++ + ++ +K+ + D+ P+ P L YI+FM R D+ ++ ++ + L+ I A+K+ ++K + E L+N L++ +QYSG + F N+A+ +H ++DL E+ ++L +L + ++Q ++K N+ P + + A+L E+I Y+ S+++ + P + L K L + +H + I Q+ + Y INA LN LL R D+C +S G+Q++YN+S E W+R + L GA+ + P+ +A QLLQ + +DA+ +C +C L+ +Q+VKILN + P + + R++ I I+ +++ D ++L T P+ P+ + +SL IP L L LT
Sbjct: 1 MREHELYVKYTRVWIPDPDEVWRSAEIIKDYKEGDTVLHLKLEDESTLEYPIGSKDNPLPFLRNPDILVGENDLTALSYLHEPAVLHNLKVRFLESNHIYTYCGIVLVAINPYEQLHIYGEEVINAYSGQNMGDMDPHIFAVAEEAFKQMARDEKNQSIIVSGESGAGKTVSAKYAMRFFATVGGSAN-------DTNVEEKVLASSPIMEAIGNAKTTRNDNSSRFGKYIQIGFDRRYHIIGANMRTYLLEKSRVVFQAEEERNYHIFYQLCASCSLPE---FKDLTLTSAEDFTYTSLGENIFIEGVNDAEDLVKTREALTMLGVKENHQMSIFKIIASILHLGNVEIVQERDGESCHINRNDTHLHHFCRLLGIEQEQMENWLCRRKLVTTSETYVKNMPHSQAVNARDALAKHIYAHLFDWIVEHINKSLHTSTK-----------------QHSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNSHVFKLEQEEYMKEQIPWTLIDFYDNQPCIDLIEAKLGILDLLDEECKVPKGTDQNWAQKLYSKH-SGSGHFEKPRMSNKSFIVVHFADKVEYQCDGFLEKNRDTVYEEQINILKASKFQLVADLFDDAK----DAAPHPGSKTSRINVRPAKPAPKGHNREHRKTVGTQFRNSLHLLMETLNATTPHYVRCIKPNDYKESFVFDSRRAVQQLRACGVLETIRISAAGYPSRWTYPDFFSRYRVLMTKKDLSVGDKKQVCKNLLEILIKDPDKFQFGKTKIFFRAGQVAYLEKLRADKFRFACIKIQKTVRGWLQRIRYRKIRKSAITLQRYGRGYLARRYAEMLRLTRAAVICQKQYRMVQVRREYLRVRRAVITIQAFTRGMFIRRLYQEFLLHHKAMIIQKTVRGWLVRKKYQRSRYAAIVIQCFYRRVRAKRQLKQLKIEARSAEHFKKLNVGMENKIVQLQKKMDNQSKELKSQNENLAVAKTVLETEVSKLSKELETL--RTRQVAGTQMTSLQEELEKLRAELQEAHAHKKLLEEEFSNEKQGLEQRVEELEKENTVLKKEKEEMNRRIQTSTQDQGGDVSQKESRLQHE-LDDERQRYQNLVKEYSRLEQRYENLQEDMSSMKF--------HPGHRRNPSNQSSLGSDSNYPSISLSEVGDTDDTIQQVEEMGIE------------KAAMDLSVFMKLQKRVRELEQERKRLQTNLDKVEELSKRKGSEAKNSTSEDDINADLAYNSLKRQELETENKKLKNDLNELRKAVAD--RASENNSSNELQDGYNLLLSQLKAANEELDVRKEEVLMLKTQIVNS--TRQTENLNHINSNDVSEWTDNKSPVNTEDRVDAPASKNKAQDWGYLNEDGELGLAYQGLKQVARLLLE---------TQLQTQTRQHRDELEALHTQIE----LLKDNLEKKQDMLDHFSTLSPDALVEFSVQQEITRLTNENLDLKELVEKLEKNEKKLKKQLRIYMKKVQELE------------VTQATKSRPELTRQFTVQRREKDFE-GMLEYYKEDEALLVKTLVTDMKPNAVSATVPC-LPAYILFMCIRHADYINDDQKVHSLLTATINAIKKVLKKNNDDFEMTSFWLANASRLLHCLKQYSGDEAFMTQNSAKQNEHCLKNFDLAEYRQVLSDLSIQIYQQLVKVAEANMQP--MIVSAMLESESIPSLAGVKPMGYRNRSSSVDCESGGPAGYTLQALIKQLAQFYSTMADHGLDPEISQQVLRQLFYSINAVTLNNLLLRKDVCSWSTGMQLRYNISQLEEWLRGKNLHQCGAVATMEPVIQAAQLLQVKKKTSQDAEAICSLCTALSLQQIVKILNLYTPLNEFEERVTVSFIRDIQNRLQ----DRIENNQLLADTKYTFPVLFPYTPSNLSLETIHIPASLSLDFLT 1837
BLAST of Dach-2 vs. Ensembl Xenopus
Match: MYO5A (myosin VA [Source:NCBI gene;Acc:100495365]) HSP 1 Score: 1109.75 bits (2869), Expect = 0.000e+0 Identity = 716/1913 (37.43%), Postives = 1075/1913 (56.19%), Query Frame = 2
Query: 47 MALYEMYSKGVKIWIPDEESVWIGATVLQFHKEKN-VIKIITDNGISKELNLSSK-KCAPFLRNPDILIGQKDLTYLSYLNEPEVLYNLQIRFCERREIYTYCGIVLVAINPYQELSIYGKEIINAYHSQNSVDLDPHIFAVAENAFRRMSSFGENQSIIVSGESGAGKTVSAKYTMRYFALVGGSKTKQSFNLTETQIERKVLLSNPILEAFGNAKTIRNDNSSRFGKYLEILFNPRNQVIGANMCTYLLEKSRVVFQNLGERNYHIFYQIVTHCQSEDELLMNTGLVNNVEMYDYLRYGESLEIDGVDDSHEFLITKNSFLQLGIDLNKFKTICEILAAILHLGNIRFRFHDATDSSIIENPELLKLIAGLLGCSIDQLKIWLCFRTISTFQETLHKPLSKAEAQYFRDAFVKTLYSNLFDWIVKQANKVLSTDVSINIKKKLKKTIVVNQEDKKKFIAVLDIYGFETFAENSFEQFCINFANEKLQLQFNLHVFKLEQEEYMNEGLEWTFIDYYNNQPCIDLIESRXXXXXXXXXXXXXXXXSDENWCCKIYSHHLNKSANFNKPKLSNMVFIIEHFAGPVEYKCAGFIEKNRDSVLEEQINLLKASDVQLIAELFRDSEIEIFDTNNXXXXXXXXXXXX---XXXXXXQENTRKMKKTVGSQFRNSLKSLMDALNKTNPHYVRCIKPNDLKLPFTFCPERAVQQLRACGVLETIRLSAAGFPSRWTYSDFYHRYYILMSNFNVKNHDFKAGSQKIVETLITVPDAFRFGNTKLFFRPGQVALLEKLRGHKIESSVTLIQSILRGSIERKKYLIIHKLTVQIQTYIRRKLAIEKATKLSQIRAVIIIQSFYRMYLARKLFVKMKCAVLAIEKWRRKIITTRLKQAYKKENCVIICQAIVRRFIQRRKFLKIQRGVILIQNHYRRRKAKETLKILKIEARSINHIKFVNKGLENKIIELTQKLDTKEKEMCXXXXXXXXXXXXXXXXXXXXXA---------ESAKIYQNTVQDLQTEIIQLKKELNREIVEKNKIFADKELLEINYKKKINYLENLIEELKSSPSVI-----EPNIICNGDEAQQSICQDEHQKFI-----------NEQMDHQKLVREYEKLEMKYENLYKEFLFVKSSNQKPSINYDNQTSNDSETESTFSKDDADVESLSDKVDAKTTKEHXXXXXXXXXXLPNFISESISTAGDLAVVMQLQMNISSLSQENNRLKETVQQFEDELLK---YEQCAEDSKGLVIHNEYD------------------NELLSIIKDIKGMDEHGLKSR----LIDEVANLKKKLKQSNEDYQKLRLHIF---------DGSMSKLTGNLDHESINSEEEELKRAFESQKEANRKMLKEIEGIKA---NNVDLKKALFQIRKDKEQLQVQLGKQHLMIRHGVEYLQNLKLTPKERLDKFVQNEISRILLENLKLQERNDQIISETIELKRGLKYFAFRLQKYEGSLVPNPNKEEDLLQLIQNVIYHSKMKTIGKRECYSEIGLIDLNMSELSIFIKSFIFDLSP-SICLQYEPYHLVPYIIFMVTRKFDFYKEEDQMTNFLSKLIVALKRTIRKRRNYIEYLVMLLSNVFCLVNLXXXXXXXXXXXXLNTAEDIQHYFVHYDLNEFIRLLKELCVTLFQMILKTIVDNLLPQSLCIDAILVHEAI--IDFLSKDGTKYKSNIETQPKNTSFNVLTKNLQSVLEILKNHKIPQLIINQIFVHIAYLINAYCLNTLLFRTDLCYFSKGLQIKYNLSSFETWIRYQKLIDSGALQCLRPMTEAVQLLQTLIDSDEDAKFVCDMCEYLNTRQVVKILNNFNPRDGYGCRLSSGLIAKIETQMKIKRGDEPSESKLETPTVIEIPIDIPFIHNGVSLCRTIIPKPLYLSCLT 5575
MA E+Y+K ++WIPD E VW A +L+ +K + V+++ + G E L +K K P LRNPDIL+G+ DLT LSYL+EP VL+NL++RF + + IYTYCGIVLVAINPY++L IYG +IINAY QN D+DPHIFAVAE A+++M+ NQSIIVSGESGAGKTVSAKY MRYFA V GS +ET +E +VL SNPI+E+ GNAKT RNDNSSRFGKY+EI F+ R +++GA+M TYLLEKSRVVFQ ERNYHIFYQ+ + ++ G N+ + Y + G S I+GVDD E T+ + LGI + I ILAAILHLGN+ F+ D+ + L + L+G +++ WLC R + T ET KP+S+ +A RDA K +Y+ LF+WIV NK L + N FI VLDIYGFETF NSFEQFCIN+ANEKLQ QFNLHVFKLEQEEYM E + WT ID+Y+NQPCI+LIE+++G+LDLLDEECK+ KGSD W K+Y+ HL KSA F KP+LSN+ FII+HFA VEY+C GF+EKN+D+V EEQI +LKAS L+ ELF++ E + T+++ P S S+ ++ +++ KKTVG QFRNSL LM+ LN T PHYVRCIKPND K PFTF +RAVQQLRACGVLETIR+SAAGFPSRWTY +F+ RY +LM +V + D K + ++E LI D ++FG TK+FFR GQVA LEK+R K+ + IQ +RG + RKKYL + K + IQ Y+R A A L + RA IIIQ F RMY+ R+ + M+ LA++ + R + Q + + I Q VR ++ R + + ++ +Q YRR AK LK LKIEARS+ H K +N G+ENKI++L +K+D + K+ + +L + ++ E AK N + LQ E+ +L+KEL + EKNKI E +K E L+ EL+ +++ E N++ E + + +D +K I +E++ +Q L+ EY +LE +Y++L E + S KP + T + +E+E TFS + + E + + ++ T D+++ ++LQ + L QE +++ + + E+++++ E+ ++G + EY+ NEL I + D G L++++ ++ ++L+ E+ LR + D + + D + + ++ E+ +A+ KE NR + +++ K N V+ + Q K++ R QNL+L P+ R++ +Q+EI+R+ ENL L E+ ++ +LK+ LK FA ++ + E + N + + + + I+ V K K G+++ + +K+ I +L P + + P L YI+FM R D+ ++ ++ + L+ I +K+ ++KR + E + LSN ++ +QYSG + F NT +H ++DL E+ ++L +L + ++Q +++ +++N+L Q + + +L HE I + + G + +++ + + + + L + I+ H + +I Q+ + Y+I A LN LL R D+C +SKG+QI+YN+S E W+R + L++S A + L P+ +A QLLQ +DEDA+ +C MC L T Q+VK+LN + P + + R+ I I+ +++ R D P +L P+ PF + ++L IP L L+ LT
Sbjct: 1 MAASELYTKHARVWIPDPEEVWKSAEILKDYKPGDTVLRLRLEEGTDLEYRLDAKTKELPPLRNPDILVGENDLTALSYLHEPAVLHNLKVRFIDSKLIYTYCGIVLVAINPYEQLPIYGSDIINAYSGQNMGDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYFATVSGSA-------SETNVEERVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRILGAHMRTYLLEKSRVVFQAEEERNYHIFYQLCASASLPEFKMLRLGTAND---FHYTKQGGSPVIEGVDDQREMKNTRQACTLLGIGDSYQMGIFRILAAILHLGNVEFKSRDSDSCLVPPKHAPLNIFCDLMGVEYEEMSHWLCHRKLVTAAETYIKPISRLQATNARDALAKHIYAFLFNWIVCHVNKALHSSTKQN-----------------SFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNLHVFKLEQEEYMKEQIPWTLIDFYDNQPCINLIEAKMGILDLLDEECKMPKGSDSTWAQKLYNTHLKKSALFEKPRLSNVAFIIKHFADKVEYQCEGFLEKNKDTVFEEQIKVLKASKFTLLTELFQEEEQILSPTSSAPPSGRTLLSRTGLRSLKPKPEQTSKEHKKTVGHQFRNSLHLLMETLNATTPHYVRCIKPNDFKYPFTFDSKRAVQQLRACGVLETIRISAAGFPSRWTYQEFFSRYRVLMKQKDVLS-DRKQTCKNVLEKLILDKDKYQFGKTKIFFRAGQVAYLEKIRADKLRMACIRIQKTIRGWLLRKKYLRMRKAAITIQRYVRGYQARCYAQFLRRTRAAIIIQKFQRMYVVRQKYRHMQSITLALQSYMRGYAARKRFQGMLRAHKATIIQKHVRGWLARVTYKRNLSAIVYLQCCYRRMMAKRELKKLKIEARSVEHYKKLNNGMENKIMQLQRKVDEQNKDNKSLLERLTHLEVTYNTEKDKLRSDVDRLRHFEEEAKNAANRMVSLQDELARLRKELQQTQTEKNKI-------EERAEKYQTETEKLVAELREQNALLKAEKEELNLLIQ--EQAKKMTEDMEKKIIEETKQLELELNDERLRYQNLLNEYSRLEERYDDLKDEINTM--SPPKPGHKRTDSTHSSNESEYTFSSEITESEDYPYRNEEPADRK---------------------TPLDMSLFLKLQKRVKELEQEKQVMQDDLDKKEEQIIRAKIMEEAKTPTRGTEL--EYESLKRQELESENKKLKNELNELRRAITEKASPDATGPGGTVYKVLLEQMTSVSEELEVRKEEVLILRSQLVSQMEAIPHKDTMTDSMVLSEDVQKMK-DKREIAQAYTGMKETNRVLESQLQSQKKAFENEVEALRGEIQALKEENN------------RQQQLLAQNLQLPPEARIEASLQHEITRLTNENLDLMEQLEKQDKTVRKLKKQLKVFAKKIGELEVGQMENVSPGQIVDEPIRPVNIPRKEKDFQ--------GMLEYKKEDELKLVKNLILELKPRGVAVNLIP-GLPAYILFMCLRHADYLNDDQKVRSLLTSTINGIKKILKKRGDDFETVSFWLSNSCRFLHCLKQYSGEEGFMKHNTTRQNEHCLTNFDLAEYRQVLSDLAIQIYQQLVR-VLENIL-QPMIVSGMLEHETIQGVSGVKPTGLRKRTSSIADEGTYTLDSIVRQLNTFHSIMCQHGMDPELIKQVVKQMFYIIGAVTLNNLLLRKDMCSWSKGMQIRYNVSQLEEWLRDKNLMNSSAKETLEPLIQAAQLLQVKKKTDEDAEAICSMCNALTTAQIVKVLNLYTPVNEFEERVLVSFIRNIQMRLR-DRKDSP---QLLMDAKHIFPVTFPFNPSSLALETIQIPGSLGLAFLT 1823
BLAST of Dach-2 vs. Ensembl Xenopus
Match: MYO5A (myosin VA [Source:NCBI gene;Acc:100495365]) HSP 1 Score: 1102.81 bits (2851), Expect = 0.000e+0 Identity = 717/1901 (37.72%), Postives = 1075/1901 (56.55%), Query Frame = 2
Query: 47 MALYEMYSKGVKIWIPDEESVWIGATVLQFHKEKN-VIKIITDNGISKELNLSSK-KCAPFLRNPDILIGQKDLTYLSYLNEPEVLYNLQIRFCERREIYTYCGIVLVAINPYQELSIYGKEIINAYHSQNSVDLDPHIFAVAENAFRRMSSFGENQSIIVSGESGAGKTVSAKYTMRYFALVGGSKTKQSFNLTETQIERKVLLSNPILEAFGNAKTIRNDNSSRFGKYLEILFNPRNQVIGANMCTYLLEKSRVVFQNLGERNYHIFYQIVTHCQSEDELLMNTGLVNNVEMYDYLRYGESLEIDGVDDSHEFLITKNSFLQLGIDLNKFKTICEILAAILHLGNIRFRFHDATDSSIIENPELLKLIAGLLGCSIDQLKIWLCFRTISTFQETLHKPLSKAEAQYFRDAFVKTLYSNLFDWIVKQANKVLSTDVSINIKKKLKKTIVVNQEDKKKFIAVLDIYGFETFAENSFEQFCINFANEKLQLQFNLHVFKLEQEEYMNEGLEWTFIDYYNNQPCIDLIESRXXXXXXXXXXXXXXXXSDENWCCKIYSHHLNKSANFNKPKLSNMVFIIEHFAGPVEYKCAGFIEKNRDSVLEEQINLLKASDVQLIAELFRDSEIEIFDTNNXXXXXXXXXXXX---XXXXXXQENTRKMKKTVGSQFRNSLKSLMDALNKTNPHYVRCIKPNDLKLPFTFCPERAVQQLRACGVLETIRLSAAGFPSRWTYSDFYHRYYILMSNFNVKNHDFKAGSQKIVETLITVPDAFRFGNTKLFFRPGQVALLEKLRGHKIESSVTLIQSILRGSIERKKYLIIHKLTVQIQTYIRRKLAIEKATKLSQIRAVIIIQSFYRMYLARKLFVKMKCAVLAIEKWRRKIITTRLKQAYKKENCVIICQAIVRRFIQRRKFLKIQRGVILIQNHYRRRKAKETLKILKIEARSINHIKFVNKGLENKIIELTQKLDTKEKEMCXXXXXXXXXXXXXXXXXXXXXA---------ESAKIYQNTVQDLQTEIIQLKKELNREIVEKNKIFADKELLEINYKKKINYLENLIEELKSSPSVIEPNIICNGDEAQQSICQDEHQ---KFINEQMDHQKLVREYEKLEMKYENLYKEFLFVKSSNQKPSINYDNQTSNDSETESTFSKDDADVESLSDKVDAKTTKEHXXXXXXXXXXLPNFISESISTAGDLAVVMQLQMNISSLSQENNRLKETVQQFEDELLK---YEQCAEDSKGLVIHNEYD------------------NELLSIIKDIKGMDEHGLKSR----LIDEVANLKKKLKQSNEDYQKLRLHIFDG--------SMSKLTGNL--DHESINSEEEELKRAFESQKEANRKMLKEIEGIKA---NNVDLKKALFQIRKDKEQLQVQLGKQHLMIRHGVEYLQNLKLTPKERLDKFVQNEISRILLENLKLQERNDQIISETIELKRGLKYFAFRLQKYEGSLVPNPNKEEDLLQLIQNVIYHSKMKTIGKRECYSEIGLIDLNMSELSIFIKSFIFDLSP-SICLQYEPYHLVPYIIFMVTRKFDFYKEEDQMTNFLSKLIVALKRTIRKRRNYIEYLVMLLSNVFCLVNLXXXXXXXXXXXXLNTAEDIQHYFVHYDLNEFIRLLKELCVTLFQMILKTIVDNLLPQSLCIDAILVHEAI--IDFLSKDGTKYKSNIETQPKNTSFNVLTKNLQSVLEILKNHKIPQLIINQIFVHIAYLINAYCLNTLLFRTDLCYFSKGLQIKYNLSSFETWIRYQKLIDSGALQCLRPMTEAVQLLQTLIDSDEDAKFVCDMCEYLNTRQVVKILNNFNPRDGYGCRLSSGLIAKIETQMKIKRGDEPSESKLETPTVIEIPIDIPFIHNGVSLCRTIIPKPLYLSCLT 5575
MA E+Y+K ++WIPD E VW A +L+ +K + V+++ + G E L +K K P LRNPDIL+G+ DLT LSYL+EP VL+NL++RF + + IYTYCGIVLVAINPY++L IYG +IINAY QN D+DPHIFAVAE A+++M+ NQSIIVSGESGAGKTVSAKY MRYFA V GS +ET +E +VL SNPI+E+ GNAKT RNDNSSRFGKY+EI F+ R +++GA+M TYLLEKSRVVFQ ERNYHIFYQ+ + ++ G N+ + Y + G S I+GVDD E T+ + LGI + I ILAAILHLGN+ F+ D +DS + ++ L + L+G +++ WLC R + T ET KP+S+ +A RDA K +Y+ LF+WIV NK L + N FI VLDIYGFETF NSFEQFCIN+ANEKLQ QFNLHVFKLEQEEYM E + WT ID+Y+NQPCI+LIE+++G+LDLLDEECK+ KGSD W K+Y+ HL KSA F KP+LSN+ FII+HFA VEY+C GF+EKN+D+V EEQI +LKAS L+ ELF++ E + T+++ P S S+ ++ +++ KKTVG QFRNSL LM+ LN T PHYVRCIKPND K PFTF +RAVQQLRACGVLETIR+SAAGFPSRWTY +F+ RY +LM +V + D K + ++E LI D ++FG TK+FFR GQVA LEK+R K+ + IQ +RG + RKKYL + K + IQ Y+R A A L + RA IIIQ F RMY+ R+ + M+ LA++ + R R +A I Q VR ++ R + + ++ +Q YRR AK LK LKIEARS+ H K +N G+ENKI++L +K+D + K+ + +L + ++ E AK N + LQ E+ +L+KEL + EKNKI E + +K + K SV + + ++ ++ I ++ Q + +E++ +Q L+ EY +LE +Y++L E N P + T + +E+E TFS + + E + + ++ T D+++ ++LQ + L QE +++ + + E+++++ E+ ++G + EY+ NEL I + D G L++++ ++ ++L+ E+ LR + S+ + NL D++ +N E+ EL ++ K+ANR + +++ K N V+ + Q K++ R QNL+L P+ R++ +Q+EI+R+ ENL L E+ ++ +LK+ LK FA ++ + E + N + + + + I+ V K K G+++ + +K+ I +L P + + P L YI+FM R D+ ++ ++ + L+ I +K+ ++KR + E + LSN ++ +QYSG + F NT +H ++DL E+ ++L +L + ++Q +++ +++N+L Q + + +L HE I + + G + +++ + + + + L + I+ H + +I Q+ + Y+I A LN LL R D+C +SKG+QI+YN+S E W+R + L++S A + L P+ +A QLLQ +DEDA+ +C MC L T Q+VK+LN + P + + R+ I I+ +++ R D P +L P+ PF + ++L IP L L+ LT
Sbjct: 1 MAASELYTKHARVWIPDPEEVWKSAEILKDYKPGDTVLRLRLEEGTDLEYRLDAKTKELPPLRNPDILVGENDLTALSYLHEPAVLHNLKVRFIDSKLIYTYCGIVLVAINPYEQLPIYGSDIINAYSGQNMGDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYFATVSGSA-------SETNVEERVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRILGAHMRTYLLEKSRVVFQAEEERNYHIFYQLCASASLPEFKMLRLGTAND---FHYTKQGGSPVIEGVDDQREMKNTRQACTLLGIGDSYQMGIFRILAAILHLGNVEFKSRD-SDSCLPKHAP-LNIFCDLMGVEYEEMSHWLCHRKLVTAAETYIKPISRLQATNARDALAKHIYAFLFNWIVCHVNKALHSSTKQN-----------------SFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNLHVFKLEQEEYMKEQIPWTLIDFYDNQPCINLIEAKMGILDLLDEECKMPKGSDSTWAQKLYNTHLKKSALFEKPRLSNVAFIIKHFADKVEYQCEGFLEKNKDTVFEEQIKVLKASKFTLLTELFQEEEQILSPTSSAPPSGRTLLSRTGLRSLKPKPEQTSKEHKKTVGHQFRNSLHLLMETLNATTPHYVRCIKPNDFKYPFTFDSKRAVQQLRACGVLETIRISAAGFPSRWTYQEFFSRYRVLMKQKDVLS-DRKQTCKNVLEKLILDKDKYQFGKTKIFFRAGQVAYLEKIRADKLRMACIRIQKTIRGWLLRKKYLRMRKAAITIQRYVRGYQARCYAQFLRRTRAAIIIQKFQRMYVVRQKYRHMQSITLALQSYMRGYAMLRAHKA-------TIIQKHVRGWLARVTYKRNLSAIVYLQCCYRRMMAKRELKKLKIEARSVEHYKKLNNGMENKIMQLQRKVDEQNKDNKSLLERLTHLEVTYNTEKDKLRSDVDRLRHFEEEAKNAANRMVSLQDELARLRKELQQTQTEKNKIEERAEKYQTETEK--------VGTDKILSSVFKHCVCLIIEDMEKKIIEETKQLELELNDERLRYQNLLNEYSRLEERYDDLKDEI------NTMPGHKRTDSTHSSNESEYTFSSEITESEDYPYRNEEPADRK---------------------TPLDMSLFLKLQKRVKELEQEKQVMQDDLDKKEEQIIRAKIMEEAKTPTRGTEL--EYESLKRQELESENKKLKNELNELRRAITEKASPDATGPGGTVYKVLLEQMTSVSEELEVRKEEVLILRSQLVSQMEAIPHKVSLETIERNLPPDYQDLN-EDGELWLVYDGLKQANRVLESQLQSQKKAFENEVEALRGEIQALKEENN------------RQQQLLAQNLQLPPEARIEASLQHEITRLTNENLDLMEQLEKQDKTVRKLKKQLKVFAKKIGELEVGQMENVSPGQIVDEPIRPVNIPRKEKDFQ--------GMLEYKKEDELKLVKNLILELKPRGVAVNLIP-GLPAYILFMCLRHADYLNDDQKVRSLLTSTINGIKKILKKRGDDFETVSFWLSNSCRFLHCLKQYSGEEGFMKHNTTRQNEHCLTNFDLAEYRQVLSDLAIQIYQQLVR-VLENIL-QPMIVSGMLEHETIQGVSGVKPTGLRKRTSSIADEGTYTLDSIVRQLNTFHSIMCQHGMDPELIKQVVKQMFYIIGAVTLNNLLLRKDMCSWSKGMQIRYNVSQLEEWLRDKNLMNSSAKETLEPLIQAAQLLQVKKKTDEDAEAICSMCNALTTAQIVKVLNLYTPVNEFEERVLVSFIRNIQMRLR-DRKDSP---QLLMDAKHIFPVTFPFNPSSLALETIQIPGSLGLAFLT 1799
BLAST of Dach-2 vs. Ensembl Xenopus
Match: MYO5A (myosin VA [Source:NCBI gene;Acc:100495365]) HSP 1 Score: 1100.5 bits (2845), Expect = 0.000e+0 Identity = 711/1899 (37.44%), Postives = 1070/1899 (56.35%), Query Frame = 2
Query: 80 KIWIPDEESVWIGATVLQFHKEKN-VIKIITDNGISKELNLSSK-KCAPFLRNPDILIGQKDLTYLSYLNEPEVLYNLQIRFCERREIYTYCGIVLVAINPYQELSIYGKEIINAYHSQNSVDLDPHIFAVAENAFRRMSSFGENQSIIVSGESGAGKTVSAKYTMRYFALVGGSKTKQSFNLTETQIERKVLLSNPILEAFGNAKTIRNDNSSRFGKYLEILFNPRNQVIGANMCTYLLEKSRVVFQNLGERNYHIFYQIVTHCQSEDELLMNTGLVNNVEMYDYLRYGESLEIDGVDDSHEFLITKNSFLQLGIDLNKFKTICEILAAILHLGNIRFRFHDATDSSIIENPELLKLIAGLLGCSIDQLKIWLCFRTISTFQETLHKPLSKAEAQYFRDAFVKTLYSNLFDWIVKQANKVLSTDVSINIKKKLKKTIVVNQEDKKKFIAVLDIYGFETFAENSFEQFCINFANEKLQLQFNLHVFKLEQEEYMNEGLEWTFIDYYNNQPCIDLIESRXXXXXXXXXXXXXXXXSDENWCCKIYSHHLNKSANFNKPKLSNMVFIIEHFAGPVEYKCAGFIEKNRDSVLEEQINLLKASDVQLIAELFRDSEIEIFDTNNXXXXXXXXXXXX---XXXXXXQENTRKMKKTVGSQFRNSLKSLMDALNKTNPHYVRCIKPNDLKLPFTFCPERAVQQLRACGVLETIRLSAAGFPSRWTYSDFYHRYYILMSNFNVKNHDFKAGSQKIVETLITVPDAFRFGNTKLFFRPGQVALLEKLRGHKIESSVTLIQSILRGSIERKKYLIIHKLTVQIQTYIRRKLAIEKATKLSQIRAVIIIQSFYRMYLARKLFVKMKCAVLAIEKWRRKIITTRLKQAYKKENCVIICQAIVRRFIQRRKFLKIQRGVILIQNHYRRRKAKETLKILKIEARSINHIKFVNKGLENKIIELTQKLDTKEKEMCXXXXXXXXXXXXXXXXXXXXXA---------ESAKIYQNTVQDLQTEIIQLKKELNREIVEKNKIFADKELLEINYKKKINYLENLIEELKSSPSVI-----EPNIICNGDEAQQSICQDEHQKFI-----------NEQMDHQKLVREYEKLEMKYENLYKEFLFVKSSNQKPSINYDNQTSNDSETESTFSKDDADVESLSDKVDAKTTKEHXXXXXXXXXXLPNFISESISTAGDLAVVMQLQMNISSLSQENNRLKETVQQFEDELLKYEQCAE--DSKGLVIHNEYDNELLSIIKDIKGMDEHGLKSR----LIDEVANLKKKLKQSNEDYQKLRLHIF---------DGSMSKLTGNLDHESINSEEEELKRAFESQKEANRKMLKEIEGIKANNVDLKKALFQIRKDKEQLQVQLGKQHLMIRHGVEYL----QNLK---------------LTPKERLDKFVQNEISRILLENLKLQERNDQIISETIELKRGLKYFAFRLQKYEGSLVPNPNKEEDLLQLIQNVIYHSKMKTIGKRECYSEIGLIDLNMSELSIFIKSFIFDLSP-SICLQYEPYHLVPYIIFMVTRKFDFYKEEDQMTNFLSKLIVALKRTIRKRRNYIEYLVMLLSNVFCLVNLXXXXXXXXXXXXLNTAEDIQHYFVHYDLNEFIRLLKELCVTLFQMILKTIVDNLLPQSLCIDAILVHEAI--IDFLSKDGTKYKSNIETQPKNTSFNVLTKNLQSVLEILKNHKIPQLIINQIFVHIAYLINAYCLNTLLFRTDLCYFSKGLQIKYNLSSFETWIRYQKLIDSGALQCLRPMTEAVQLLQTLIDSDEDAKFVCDMCEYLNTRQVVKILNNFNPRDGYGCRLSSGLIAKIETQMKIKRGDEPSESKLETPTVIEIPIDIPFIHNGVSLCRTIIPKPLYLSCLT 5575
++WIPD E VW A +L+ +K + V+++ + G E L +K K P LRNPDIL+G+ DLT LSYL+EP VL+NL++RF + + IYTYCGIVLVAINPY++L IYG +IINAY QN D+DPHIFAVAE A+++M+ NQSIIVSGESGAGKTVSAKY MRYFA V GS +ET +E +VL SNPI+E+ GNAKT RNDNSSRFGKY+EI F+ R +++GA+M TYLLEKSRVVFQ ERNYHIFYQ+ + ++ G N+ + Y + G S I+GVDD E T+ + LGI + I ILAAILHLGN+ F+ D+ + L + L+G +++ WLC R + T ET KP+S+ +A RDA K +Y+ LF+WIV NK L + N FI VLDIYGFETF NSFEQFCIN+ANEKLQ QFNLHVFKLEQEEYM E + WT ID+Y+NQPCI+LIE+++G+LDLLDEECK+ KGSD W K+Y+ HL KSA F KP+LSN+ FII+HFA VEY+C GF+EKN+D+V EEQI +LKAS L+ ELF++ E + T+++ P S S+ ++ +++ KKTVG QFRNSL LM+ LN T PHYVRCIKPND K PFTF +RAVQQLRACGVLETIR+SAAGFPSRWTY +F+ RY +LM +V + D K + ++E LI D ++FG TK+FFR GQVA LEK+R K+ + IQ +RG + RKKYL + K + IQ Y+R A A L + RA IIIQ F RMY+ R+ + M+ LA++ + R + Q + + I Q VR ++ R + + ++ +Q YRR AK LK LKIEARS+ H K +N G+ENKI++L +K+D + K+ + +L + ++ E AK N + LQ E+ +L+KEL + EKNKI E +K E L+ EL+ +++ E N++ E + + +D +K I +E++ +Q L+ EY +LE +Y++L E + KP + T + +E+E TFS + + E + + ++ T D+++ ++LQ + L QE +++ + + E+++++ + + +S+ + NE NEL I + D G L++++ ++ ++L+ E+ LR + D + + D + + ++ E+ +A+ KE NR + + + + + +L +++ L+ QL Q + VE L Q LK L P+ R++ +Q+EI+R+ ENL L E+ ++ +LK+ LK FA ++ + E + N + + + + I+ V K K G+++ + +K+ I +L P + + P L YI+FM R D+ ++ ++ + L+ I +K+ ++KR + E + LSN ++ +QYSG + F NT +H ++DL E+ ++L +L + ++Q +++ +++N+L Q + + +L HE I + + G + +++ + + + + L + I+ H + +I Q+ + Y+I A LN LL R D+C +SKG+QI+YN+S E W+R + L++S A + L P+ +A QLLQ +DEDA+ +C MC L T Q+VK+LN + P + + R+ I I+ +++ R D P +L P+ PF + ++L IP L L+ LT
Sbjct: 8 QVWIPDPEEVWKSAEILKDYKPGDTVLRLRLEEGTDLEYRLDAKTKELPPLRNPDILVGENDLTALSYLHEPAVLHNLKVRFIDSKLIYTYCGIVLVAINPYEQLPIYGSDIINAYSGQNMGDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYFATVSGSA-------SETNVEERVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRILGAHMRTYLLEKSRVVFQAEEERNYHIFYQLCASASLPEFKMLRLGTAND---FHYTKQGGSPVIEGVDDQREMKNTRQACTLLGIGDSYQMGIFRILAAILHLGNVEFKSRDSDSCLVPPKHAPLNIFCDLMGVEYEEMSHWLCHRKLVTAAETYIKPISRLQATNARDALAKHIYAFLFNWIVCHVNKALHSSTKQN-----------------SFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNLHVFKLEQEEYMKEQIPWTLIDFYDNQPCINLIEAKMGILDLLDEECKMPKGSDSTWAQKLYNTHLKKSALFEKPRLSNVAFIIKHFADKVEYQCEGFLEKNKDTVFEEQIKVLKASKFTLLTELFQEEEQILSPTSSAPPSGRTLLSRTGLRSLKPKPEQTSKEHKKTVGHQFRNSLHLLMETLNATTPHYVRCIKPNDFKYPFTFDSKRAVQQLRACGVLETIRISAAGFPSRWTYQEFFSRYRVLMKQKDVLS-DRKQTCKNVLEKLILDKDKYQFGKTKIFFRAGQVAYLEKIRADKLRMACIRIQKTIRGWLLRKKYLRMRKAAITIQRYVRGYQARCYAQFLRRTRAAIIIQKFQRMYVVRQKYRHMQSITLALQSYMRGYAARKRFQGMLRAHKATIIQKHVRGWLARVTYKRNLSAIVYLQCCYRRMMAKRELKKLKIEARSVEHYKKLNNGMENKIMQLQRKVDEQNKDNKSLLERLTHLEVTYNTEKDKLRSDVDRLRHFEEEAKNAANRMVSLQDELARLRKELQQTQTEKNKI-------EERAEKYQTETEKLVAELREQNALLKAEKEELNLLIQ--EQAKKMTEDMEKKIIEETKQLELELNDERLRYQNLLNEYSRLEERYDDLKDEINTMVPP--KPGHKRTDSTHSSNESEYTFSSEITESEDYPYRNEEPADRK---------------------TPLDMSLFLKLQKRVKELEQEKQVMQDDLDKKEEQIIRAKIMRQELESENKKLKNEL-NELRRAITEKASPDATGPGGTVYKVLLEQMTSVSEELEVRKEEVLILRSQLVSQMEAIPHKDTMTDSMVLSEDVQKM-KDKREIAQAYTGMKETNRNLPPDYQDLNEDG-ELWLVYDGLKQANRVLESQLQSQKKAFENEVEALRGEIQALKEENNRQQQLLAQNLQLPPEARIEASLQHEITRLTNENLDLMEQLEKQDKTVRKLKKQLKVFAKKIGELEVGQMENVSPGQIVDEPIRPVNIPRKEKDFQ--------GMLEYKKEDELKLVKNLILELKPRGVAVNLIP-GLPAYILFMCLRHADYLNDDQKVRSLLTSTINGIKKILKKRGDDFETVSFWLSNSCRFLHCLKQYSGEEGFMKHNTTRQNEHCLTNFDLAEYRQVLSDLAIQIYQQLVR-VLENIL-QPMIVSGMLEHETIQGVSGVKPTGLRKRTSSIADEGTYTLDSIVRQLNTFHSIMCQHGMDPELIKQVVKQMFYIIGAVTLNNLLLRKDMCSWSKGMQIRYNVSQLEEWLRDKNLMNSSAKETLEPLIQAAQLLQVKKKTDEDAEAICSMCNALTTAQIVKVLNLYTPVNEFEERVLVSFIRNIQMRLR-DRKDSP---QLLMDAKHIFPVTFPFNPSSLALETIQIPGSLGLAFLT 1828
BLAST of Dach-2 vs. Ensembl Xenopus
Match: MYO5A (myosin VA [Source:NCBI gene;Acc:100495365]) HSP 1 Score: 1097.8 bits (2838), Expect = 0.000e+0 Identity = 710/1903 (37.31%), Postives = 1067/1903 (56.07%), Query Frame = 2
Query: 77 VKIWIPDEESVWIGATVLQFHKEKN-VIKIITDNGISKELNLSSK-KCAPFLRNPDILIGQKDLTYLSYLNEPEVLYNLQIRFCERREIYTYCGIVLVAINPYQELSIYGKEIINAYHSQNSVDLDPHIFAVAENAFRRMSSFGENQSIIVSGESGAGKTVSAKYTMRYFALVGGSKTKQSFNLTETQIERKVLLSNPILEAFGNAKTIRNDNSSRFGKYLEILFNPRNQVIGANMCTYLLEKSRVVFQNLGERNYHIFYQIVTHCQSEDELLMNTGLVNNVEMYDYLRYGESLEIDGVDDSHEFLITKNSFLQLGIDLNKFKTICEILAAILHLGNIRFRFHDATDSSIIENPELLKLIAGLLGCSIDQLKIWLCFRTISTFQETLHKPLSKAEAQYFRDAFVKTLYSNLFDWIVKQANKVLSTDVSINIKKKLKKTIVVNQEDKKKFIAVLDIYGFETFAENSFEQFCINFANEKLQLQFNLHVFKLEQEEYMNEGLEWTFIDYYNNQPCIDLIESRXXXXXXXXXXXXXXXXSDENWCCKIYSHHLNKSANFNKPKLSNMVFIIEHFAGPVEYKCAGFIEKNRDSVLEEQINLLKASDVQLIAELFRDSEIEIFDTNNXXXXXXXXXXXX---XXXXXXQENTRKMKKTVGSQFRNSLKSLMDALNKTNPHYVRCIKPNDLKLPFTFCPERAVQQLRACGVLETIRLSAAGFPSRWTYSDFYHRYYILMSNFNVKNHDFKAGSQKIVETLITVPDAFRFGNTKLFFRPGQVALLEKLRGHKIESSVTLIQSILRGSIERKKYLIIHKLTVQIQTYIRRKLAIEKATKLSQIRAVIIIQSFYRMYLARKLFVKMKCAVLAIEKWRRKIITTRLKQAYKKENCVIICQAIVRRFIQRRKFLKIQRGVILIQNHYRRRKAKETLKILKIEARSINHIKFVNKGLENKIIELTQKLDTKEKEMCXXXXXXXXXXXXXXXXXXXXXA---------ESAKIYQNTVQDLQTEIIQLKKELNREIVEKNKIFADKELLEINYKKKINYLENLIEELKSSPSVI-----EPNIICNGDEAQQSICQDEHQKFI-----------NEQMDHQKLVREYEKLEMKYENLYKEFLFVKSSNQKPSINYDNQTSNDSETESTFSKDDADVESLSDKVDAKTTKEHXXXXXXXXXXLPNFISESISTAGDLAVVMQLQMNISSLSQENNRLKETVQQFEDELLK---YEQCAEDSKGLVIHNEYD------------------NELLSIIKDIKGMDEHGLKSR----LIDEVANLKKKLKQSNEDYQKLRLHIF---------DGSMSKLTGNLDHESINSEEEELKRAFESQKEANRKMLKEIEGIKA---NNVDLKKALFQIRKDKEQLQVQLGKQHLMIRHGVEYLQNLKLTPKERLDKFVQNEISRILLENLKLQERNDQIISETIELKRGLKYFAFRLQKYEGSLVPNPNKEEDLLQLIQNVIYHSKMKTIGKRECYSEIGLIDLNMSELSIFIKSFIFDLSP-SICLQYEPYHLVPYIIFMVTRKFDFYKEEDQMTNFLSKLIVALKRTIRKRRNYIEYLVMLLSNVFCLVNLXXXXXXXXXXXXLNTAEDIQHYFVHYDLNEFIRLLKELCVTLFQMILKTIVDNLLPQSLCIDAILVHEAI--IDFLSKDGTKYKSNIETQPKNTSFNVLTKNLQSVLEILKNHKIPQLIINQIFVHIAYLINAYCLNTLLFRTDLCYFSKGLQIKYNLSSFETWIRYQKLIDSGALQCLRPMTEAVQLLQTLIDSDEDAKFVCDMCEYLNTRQVVKILNNFNPRDGYGCRLSSGLIAKIETQMKIKRGDEPSESKLETPTVIEIPIDIPFIHNGVSLCRTIIPKPLYLSCLT 5575
++WIPD E VW A +L+ +K + V+++ + G E L +K K P LRNPDIL+G+ DLT LSYL+EP VL+NL++RF + + IYTYCGIVLVAINPY++L IYG +IINAY QN D+DPHIFAVAE A+++M+ NQSIIVSGESGAGKTVSAKY MRYFA V GS +ET +E +VL SNPI+E+ GNAKT RNDNSSRFGKY+EI F+ R +++GA+M TYLLEKSRVVFQ ERNYHIFYQ+ + ++ G N+ + Y + G S I+GVDD E T+ + LGI + I ILAAILHLGN+ F+ D+ + L + L+G +++ WLC R + T ET KP+S+ +A RDA K +Y+ LF+WIV NK L + N FI VLDIYGFETF NSFEQFCIN+ANEKLQ QFNLHVFKLEQEEYM E + WT ID+Y+NQPCI+LIE+++G+LDLLDEECK+ KGSD W K+Y+ HL KSA F KP+LSN+ FII+HFA VEY+C GF+EKN+D+V EEQI +LKAS L+ ELF++ E + T+++ P S S+ ++ +++ KKTVG QFRNSL LM+ LN T PHYVRCIKPND K PFTF +RAVQQLRACGVLETIR+SAAGFPSRWTY +F+ RY +LM +V + D K + ++E LI D ++FG TK+FFR GQVA LEK+R K+ + IQ +RG + RKKYL + K + IQ Y+R A A L + RA IIIQ F RMY+ R+ + M+ LA++ + R + Q + + I Q VR ++ R + + ++ +Q YRR AK LK LKIEARS+ H K +N G+ENKI++L +K+D + K+ + +L + ++ E AK N + LQ E+ +L+KEL + EKNKI E +K E L+ EL+ +++ E N++ E + + +D +K I +E++ +Q L+ EY +LE +Y++L E + KP + T + +E+E TFS + + E + + ++ T D+++ ++LQ + L QE +++ + + E+++++ E+ ++G + EY+ NEL I + D G L++++ ++ ++L+ E+ LR + D + + D + + ++ E+ +A+ KE NR + +++ K N V+ + Q K++ R QNL+L P+ R++ +Q+EI+R+ ENL L E+ ++ +LK+ LK FA ++ + E + N + + + + I+ V K K G+++ + +K+ I +L P + + P L YI+FM R D+ ++ ++ + L+ I +K+ ++KR + E + LSN ++ +QYSG + F NT +H ++DL E+ ++L +L + ++Q +++ +++N+L Q + + +L HE I + + G + +++ + + + + L + I+ H + +I Q+ + Y+I A LN LL R D+C +SKG+QI+YN+S E W+R + L++S A + L P+ +A QLLQ +DEDA+ +C MC L T Q+VK+LN + P + + R+ I I+ +++ R D P +L P+ PF + ++L IP L L+ LT
Sbjct: 17 ARVWIPDPEEVWKSAEILKDYKPGDTVLRLRLEEGTDLEYRLDAKTKELPPLRNPDILVGENDLTALSYLHEPAVLHNLKVRFIDSKLIYTYCGIVLVAINPYEQLPIYGSDIINAYSGQNMGDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYFATVSGSA-------SETNVEERVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRILGAHMRTYLLEKSRVVFQAEEERNYHIFYQLCASASLPEFKMLRLGTAND---FHYTKQGGSPVIEGVDDQREMKNTRQACTLLGIGDSYQMGIFRILAAILHLGNVEFKSRDSDSCLVPPKHAPLNIFCDLMGVEYEEMSHWLCHRKLVTAAETYIKPISRLQATNARDALAKHIYAFLFNWIVCHVNKALHSSTKQN-----------------SFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNLHVFKLEQEEYMKEQIPWTLIDFYDNQPCINLIEAKMGILDLLDEECKMPKGSDSTWAQKLYNTHLKKSALFEKPRLSNVAFIIKHFADKVEYQCEGFLEKNKDTVFEEQIKVLKASKFTLLTELFQEEEQILSPTSSAPPSGRTLLSRTGLRSLKPKPEQTSKEHKKTVGHQFRNSLHLLMETLNATTPHYVRCIKPNDFKYPFTFDSKRAVQQLRACGVLETIRISAAGFPSRWTYQEFFSRYRVLMKQKDVLS-DRKQTCKNVLEKLILDKDKYQFGKTKIFFRAGQVAYLEKIRADKLRMACIRIQKTIRGWLLRKKYLRMRKAAITIQRYVRGYQARCYAQFLRRTRAAIIIQKFQRMYVVRQKYRHMQSITLALQSYMRGYAARKRFQGMLRAHKATIIQKHVRGWLARVTYKRNLSAIVYLQCCYRRMMAKRELKKLKIEARSVEHYKKLNNGMENKIMQLQRKVDEQNKDNKSLLERLTHLEVTYNTEKDKLRSDVDRLRHFEEEAKNAANRMVSLQDELARLRKELQQTQTEKNKI-------EERAEKYQTETEKLVAELREQNALLKAEKEELNLLIQ--EQAKKMTEDMEKKIIEETKQLELELNDERLRYQNLLNEYSRLEERYDDLKDEINTMVPP--KPGHKRTDSTHSSNESEYTFSSEITESEDYPYRNEEPADRK---------------------TPLDMSLFLKLQKRVKELEQEKQVMQDDLDKKEEQIIRAKIMEEAKTPTRGTEL--EYESLKRQELESENKKLKNELNELRRAITEKASPDATGPGGTVYKVLLEQMTSVSEELEVRKEEVLILRSQLVSQMEAIPHKDTMTDSMVLSEDVQKMK-DKREIAQAYTGMKETNRVLESQLQSQKKAFENEVEALRGEIQALKEENN------------RQQQLLAQNLQLPPEARIEASLQHEITRLTNENLDLMEQLEKQDKTVRKLKKQLKVFAKKIGELEVGQMENVSPGQIVDEPIRPVNIPRKEKDFQ--------GMLEYKKEDELKLVKNLILELKPRGVAVNLIP-GLPAYILFMCLRHADYLNDDQKVRSLLTSTINGIKKILKKRGDDFETVSFWLSNSCRFLHCLKQYSGEEGFMKHNTTRQNEHCLTNFDLAEYRQVLSDLAIQIYQQLVR-VLENIL-QPMIVSGMLEHETIQGVSGVKPTGLRKRTSSIADEGTYTLDSIVRQLNTFHSIMCQHGMDPELIKQVVKQMFYIIGAVTLNNLLLRKDMCSWSKGMQIRYNVSQLEEWLRDKNLMNSSAKETLEPLIQAAQLLQVKKKTDEDAEAICSMCNALTTAQIVKVLNLYTPVNEFEERVLVSFIRNIQMRLR-DRKDSP---QLLMDAKHIFPVTFPFNPSSLALETIQIPGSLGLAFLT 1829
BLAST of Dach-2 vs. Ensembl Xenopus
Match: MYO5A (myosin VA [Source:NCBI gene;Acc:100495365]) HSP 1 Score: 1097.03 bits (2836), Expect = 0.000e+0 Identity = 719/1934 (37.18%), Postives = 1075/1934 (55.58%), Query Frame = 2
Query: 80 KIWIPDEESVWIGATVLQFHKEKN-VIKIITDNGISKELNLSSK-KCAPFLRNPDILIGQKDLTYLSYLNEPEVLYNLQIRFCERREIYTYCGIVLVAINPYQELSIYGKEIINAYHSQNSVDLDPHIFAVAENAFRRMSSFGENQSIIVSGESGAGKTVSAKYTMRYFALVGGSKTKQSFNLTETQIERKVLLSNPILEAFGNAKTIRNDNSSRFGKYLEILFNPRNQVIGANMCTYLLEKSRVVFQNLGERNYHIFYQIVTHCQSEDELLMNTGLVNNVEMYDYLRYGESLEIDGVDDSHEFLITKNSFLQLGIDLNKFKTICEILAAILHLGNIRFRFHDATDSSIIENPELLKLIAGLLGCSIDQLKIWLCFRTISTFQETLHKPLSKAEAQYFRDAFVKTLYSNLFDWIVKQANKVLSTDVSINIKKKLKKTIVVNQEDKKKFIAVLDIYGFETFAENSFEQFCINFANEKLQLQFNLHVFKLEQEEYMNEGLEWTFIDYYNNQPCIDLIESRXXXXXXXXXXXXXXXXSDENWCCKIYSHHLNKSANFNKPKLSNMVFIIEHFAGPVEYKCAGFIEKNRDSVLEEQINLLKASDVQLIAELFRDSEIEIFDTNNXXXXXXXXXXXX---XXXXXXQENTRKMKKTVGSQFRNSLKSLMDALNKTNPHYVRCIKPNDLKLPFTFCPERAVQQLRACGVLETIRLSAAGFPSRWTYSDFYHRYYILMSNFNVKNHDFKAGSQKIVETLITVPDAFRFGNTKLFFRPGQVALLEKLRGHKIESSVTLIQSILRGSIERKKYLIIHKLTVQIQTYIRRKLAIEKATKLSQIRAVIIIQSFYRMYLARKLFVKMKCAVLAIEKWRRKIITTRLKQAYKKENCVIICQAIVRRFIQRRKFLKIQRGVILIQNHYRRRKAKETLKILKIEARSINHIKFVNKGLENKIIELTQKLDTKEKEMCXXXXXXXXXXXXXXXXXXXXXA---------ESAKIYQNTVQDLQTEIIQLKKELNREIVEKNKIFADKELLEINYKKKINYLENLIEELKSSPSVI-----EPNIICNGDEAQQSICQDEHQKFI-----------NEQMDHQKLVREYEKLEMKYENLYKEFLFVKSSNQKPSINYDNQTSNDSETESTFSKDDADVESLSDKVDAKTTKEHXXXXXXXXXXLPNFISESISTAGDLAVVMQLQMNISSLSQENNRLKETVQQFEDELLK---YEQCAEDSKGLVIHNEYD------------------NELLSIIKDIKGMDEHG-----------------------------LKSRLIDEVANLKKKLKQSN---------EDYQKLR-----LHIFDGSMSKLTGNL--DHESINSEEEELKRAFESQKEANRKMLKEIEGIKA---NNVDLKKALFQIRKDKEQLQVQLGKQHLMIRHGVEYLQNLKLTPKERLDKFVQNEISRILLENLKLQERNDQIISETIELKRGLKYFAFRLQKYEGSLVPNPNKEEDLLQLIQNVIYHSKMKTIGKRECYSEIGLIDLNMSELSIFIKSFIFDLSP-SICLQYEPYHLVPYIIFMVTRKFDFYKEEDQMTNFLSKLIVALKRTIRKRRNYIEYLVMLLSNVFCLVNLXXXXXXXXXXXXLNTAEDIQHYFVHYDLNEFIRLLKELCVTLFQMILKTIVDNLLPQSLCIDAILVHEAI--IDFLSKDGTKYKSNIETQPKNTSFNVLTKNLQSVLEILKNHKIPQLIINQIFVHIAYLINAYCLNTLLFRTDLCYFSKGLQIKYNLSSFETWIRYQKLIDSGALQCLRPMTEAVQLLQTLIDSDEDAKFVCDMCEYLNTRQVVKILNNFNPRDGYGCRLSSGLIAKIETQMKIKRGDEPSESKLETPTVIEIPIDIPFIHNGVSLCRTIIPKPLYLSCLT 5575
++WIPD E VW A +L+ +K + V+++ + G E L +K K P LRNPDIL+G+ DLT LSYL+EP VL+NL++RF + + IYTYCGIVLVAINPY++L IYG +IINAY QN D+DPHIFAVAE A+++M+ NQSIIVSGESGAGKTVSAKY MRYFA V GS +ET +E +VL SNPI+E+ GNAKT RNDNSSRFGKY+EI F+ R +++GA+M TYLLEKSRVVFQ ERNYHIFYQ+ + ++ G N+ + Y + G S I+GVDD E T+ + LGI + I ILAAILHLGN+ F+ D+ + L + L+G +++ WLC R + T ET KP+S+ +A RDA K +Y+ LF+WIV NK L + N FI VLDIYGFETF NSFEQFCIN+ANEKLQ QFNLHVFKLEQEEYM E + WT ID+Y+NQPCI+LIE+++G+LDLLDEECK+ KGSD W K+Y+ HL KSA F KP+LSN+ FII+HFA VEY+C GF+EKN+D+V EEQI +LKAS L+ ELF++ E + T+++ P S S+ ++ +++ KKTVG QFRNSL LM+ LN T PHYVRCIKPND K PFTF +RAVQQLRACGVLETIR+SAAGFPSRWTY +F+ RY +LM +V + D K + ++E LI D ++FG TK+FFR GQVA LEK+R K+ + IQ +RG + RKKYL + K + IQ Y+R A A L + RA IIIQ F RMY+ R+ + M+ LA++ + R + Q + + I Q VR ++ R + + ++ +Q YRR AK LK LKIEARS+ H K +N G+ENKI++L +K+D + K+ + +L + ++ E AK N + LQ E+ +L+KEL + EKNKI E +K E L+ EL+ +++ E N++ E + + +D +K I +E++ +Q L+ EY +LE +Y++L E + KP + T + +E+E TFS + + E + + ++ T D+++ ++LQ + L QE +++ + + E+++++ E+ ++G + EY+ NEL I + D G L+S+L+ ++ + K + S+ ED QK++ + G M + NL D++ +N E+ EL ++ K+ANR + +++ K N V+ + Q K++ R QNL+L P+ R++ +Q+EI+R+ ENL L E+ ++ +LK+ LK FA ++ + E + N + + + + I+ V K K G+++ + +K+ I +L P + + P L YI+FM R D+ ++ ++ + L+ I +K+ ++KR + E + LSN ++ +QYSG + F NT +H ++DL E+ ++L +L + ++Q +++ +++N+L Q + + +L HE I + + G + +++ + + + + L + I+ H + +I Q+ + Y+I A LN LL R D+C +SKG+QI+YN+S E W+R + L++S A + L P+ +A QLLQ +DEDA+ +C MC L T Q+VK+LN + P + + R+ I I+ +++ R D P +L P+ PF + ++L IP L L+ LT
Sbjct: 8 QVWIPDPEEVWKSAEILKDYKPGDTVLRLRLEEGTDLEYRLDAKTKELPPLRNPDILVGENDLTALSYLHEPAVLHNLKVRFIDSKLIYTYCGIVLVAINPYEQLPIYGSDIINAYSGQNMGDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYFATVSGSA-------SETNVEERVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRILGAHMRTYLLEKSRVVFQAEEERNYHIFYQLCASASLPEFKMLRLGTAND---FHYTKQGGSPVIEGVDDQREMKNTRQACTLLGIGDSYQMGIFRILAAILHLGNVEFKSRDSDSCLVPPKHAPLNIFCDLMGVEYEEMSHWLCHRKLVTAAETYIKPISRLQATNARDALAKHIYAFLFNWIVCHVNKALHSSTKQN-----------------SFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNLHVFKLEQEEYMKEQIPWTLIDFYDNQPCINLIEAKMGILDLLDEECKMPKGSDSTWAQKLYNTHLKKSALFEKPRLSNVAFIIKHFADKVEYQCEGFLEKNKDTVFEEQIKVLKASKFTLLTELFQEEEQILSPTSSAPPSGRTLLSRTGLRSLKPKPEQTSKEHKKTVGHQFRNSLHLLMETLNATTPHYVRCIKPNDFKYPFTFDSKRAVQQLRACGVLETIRISAAGFPSRWTYQEFFSRYRVLMKQKDVLS-DRKQTCKNVLEKLILDKDKYQFGKTKIFFRAGQVAYLEKIRADKLRMACIRIQKTIRGWLLRKKYLRMRKAAITIQRYVRGYQARCYAQFLRRTRAAIIIQKFQRMYVVRQKYRHMQSITLALQSYMRGYAARKRFQGMLRAHKATIIQKHVRGWLARVTYKRNLSAIVYLQCCYRRMMAKRELKKLKIEARSVEHYKKLNNGMENKIMQLQRKVDEQNKDNKSLLERLTHLEVTYNTEKDKLRSDVDRLRHFEEEAKNAANRMVSLQDELARLRKELQQTQTEKNKI-------EERAEKYQTETEKLVAELREQNALLKAEKEELNLLIQ--EQAKKMTEDMEKKIIEETKQLELELNDERLRYQNLLNEYSRLEERYDDLKDEINTMVPP--KPGHKRTDSTHSSNESEYTFSSEITESEDYPYRNEEPADRK---------------------TPLDMSLFLKLQKRVKELEQEKQVMQDDLDKKEEQIIRAKIMEEAKTPTRGTEL--EYESLKRQELESENKKLKNELNELRRAITEKASPDATGPGGTVYKVLLEQMTSVSEELEVRKEEVLILRSQLVSQMEAIPHKPRPSDTMTDSMVLSEDVQKMKDKREIAQAYTG-MKETNRNLPPDYQDLN-EDGELWLVYDGLKQANRVLESQLQSQKKAFENEVEALRGEIQALKEENN------------RQQQLLAQNLQLPPEARIEASLQHEITRLTNENLDLMEQLEKQDKTVRKLKKQLKVFAKKIGELEVGQMENVSPGQIVDEPIRPVNIPRKEKDFQ--------GMLEYKKEDELKLVKNLILELKPRGVAVNLIP-GLPAYILFMCLRHADYLNDDQKVRSLLTSTINGIKKILKKRGDDFETVSFWLSNSCRFLHCLKQYSGEEGFMKHNTTRQNEHCLTNFDLAEYRQVLSDLAIQIYQQLVR-VLENIL-QPMIVSGMLEHETIQGVSGVKPTGLRKRTSSIADEGTYTLDSIVRQLNTFHSIMCQHGMDPELIKQVVKQMFYIIGAVTLNNLLLRKDMCSWSKGMQIRYNVSQLEEWLRDKNLMNSSAKETLEPLIQAAQLLQVKKKTDEDAEAICSMCNALTTAQIVKVLNLYTPVNEFEERVLVSFIRNIQMRLR-DRKDSP---QLLMDAKHIFPVTFPFNPSSLALETIQIPGSLGLAFLT 1850
BLAST of Dach-2 vs. Ensembl Mouse
Match: Myo5a (myosin VA [Source:MGI Symbol;Acc:MGI:105976]) HSP 1 Score: 1109.36 bits (2868), Expect = 0.000e+0 Identity = 710/1902 (37.33%), Postives = 1083/1902 (56.94%), Query Frame = 2
Query: 47 MALYEMYSKGVKIWIPDEESVWIGATVLQFHKEKN-VIKIITDNGISKELNLSSKKCA-PFLRNPDILIGQKDLTYLSYLNEPEVLYNLQIRFCERREIYTYCGIVLVAINPYQELSIYGKEIINAYHSQNSVDLDPHIFAVAENAFRRMSSFGENQSIIVSGESGAGKTVSAKYTMRYFALVGGSKTKQSFNLTETQIERKVLLSNPILEAFGNAKTIRNDNSSRFGKYLEILFNPRNQVIGANMCTYLLEKSRVVFQNLGERNYHIFYQIVTHCQSEDELLMNTGLVNNVEMYDYLRYGESLEIDGVDDSHEFLITKNSFLQLGIDLNKFKTICEILAAILHLGNIRFRFHDATDSSIIENPELLKLIAGLLGCSIDQLKIWLCFRTISTFQETLHKPLSKAEAQYFRDAFVKTLYSNLFDWIVKQANKVLSTDVSINIKKKLKKTIVVNQEDKKKFIAVLDIYGFETFAENSFEQFCINFANEKLQLQFNLHVFKLEQEEYMNEGLEWTFIDYYNNQPCIDLIESRXXXXXXXXXXXXXXXXSDENWCCKIYSHHLNKSANFNKPKLSNMVFIIEHFAGPVEYKCAGFIEKNRDSVLEEQINLLKASDVQLIAELFRDSEIEIFDTNNXXXXXXXXXXXXXXXXXXQ--ENTRKMKKTVGSQFRNSLKSLMDALNKTNPHYVRCIKPNDLKLPFTFCPERAVQQLRACGVLETIRLSAAGFPSRWTYSDFYHRYYILMSNFNVKNHDFKAGSQKIVETLITVPDAFRFGNTKLFFRPGQVALLEKLRGHKIESSVTLIQSILRGSIERKKYLIIHKLTVQIQTYIRRKLAIEKATKLSQIRAVIIIQSFYRMYLARKLFVKMKCAVLAIEKWRRKIITTRLKQAYKKENCVIICQAIVRRFIQRRKFLKIQRGVILIQNHYRRRKAKETLKILKIEARSINHIKFVNKGLENKIIELTQKLDTKEKEM-CXXXXXX--------XXXXXXXXXXXXXXXAESAKIYQNTVQDLQTEIIQLKKELNREIVEKNKI--FADKELLEINYKKKINYL-ENLIEE---LKSSPSVIEPNIICNGDEAQQSICQD--EHQKFI-----NEQMDHQKLVREYEKLEMKYENLYKEFLFVKSSNQKPSINYDNQTSNDSETESTFSKDDADVESLSDKVDAKTTKEHXXXXXXXXXXLPNFISESISTAGDLAVVMQLQMNISSLSQENNRLKETVQQFEDELLKYEQCAEDSKGLVIHNEYDNELLSIIKDIKGMDEHGLKSRLIDEVANLKKKL-KQSNEDYQKLRLHIFDGSMSKLTGNLDHESINSEEEELKRA-FESQKEANRK------------MLKEIEGIKANNVDLKKALFQIRKDKEQLQVQLGKQHLMIRHGVEYL----QNLK---------------LTPKERLDKFVQNEISRILLENLKLQERNDQIISETIELKRGLKYFAFRLQKYEGSLVPNPNKEEDLLQLIQNVIYHSKMKTIGKRECYSEIGLIDLNMSELSIFIKSFIFDLSP-SICLQYEPYHLVPYIIFMVTRKFDFYKEEDQMTNFLSKLIVALKRTIRKRRNYIEYLVMLLSNVFCLVNLXXXXXXXXXXXXLNTAEDIQHYFVHYDLNEFIRLLKELCVTLFQMILKTIVDNLLPQSLCIDAILVHEAI--IDFLSKDGTKYKSNIETQPKNTSFNVLTKNLQSVLEILKNHKIPQLIINQIFVHIAYLINAYCLNTLLFRTDLCYFSKGLQIKYNLSSFETWIRYQKLIDSGALQCLRPMTEAVQLLQTLIDSDEDAKFVCDMCEYLNTRQVVKILNNFNPRDGYGCRLSSGLIAKIETQMKIKRGDEPSESKLETPTVIEIPIDIPFIHNGVSLCRTIIPKPLYLS 5566
MA E+Y+K ++WIPD E VW A +L+ +K + V+ + + G E L K P LRNPDIL+G+ DLT LSYL+EP VL+NL++RF + + IYTYCGIVLVAINPY++L IYG++IINAY QN D+DPHIFAVAE A+++M+ NQSIIVSGESGAGKTVSAKY MRYFA V GS +E +E KVL SNPI+E+ GNAKT RNDNSSRFGKY+EI F+ R ++IGANM TYLLEKSRVVFQ ERNYHIFYQ+ + + ++ G N + + Y + G S I+GVDD+ E T+ + LGI + I ILA ILHLGN+ F D+ +I E L + L+G +++ WLC R ++T ET KP+SK +A RDA K +Y+ LF+WIV N+ L + V + FI VLDIYGFETF NSFEQFCIN+ANEKLQ QFN+HVFKLEQEEYM E + WT ID+Y+NQPCI+LIES+LG+LDLLDEECK+ KG+D+ W K+Y+ HLNK A F KP++SN FII+HFA VEY+C GF+EKN+D+V EEQI +LK+S +++ ELF+D E I T+ + + + + + + ++ KKTVG QFRNSL LM+ LN T PHYVRCIKPND K PFTF +RAVQQLRACGVLETIR+SAAGFPSRWTY +F+ RY +LM +V D K + ++E LI D ++FG TK+FFR GQVA LEKLR K+ ++ IQ +RG + RK+YL + + + +Q Y+R A A L + +A IQ ++RMY+ R+ + + A + I+ + R +T + +E +I Q VR ++ R + + + ++ +Q +RR AK LK LKIEARS+ K ++ G+ENKI++L +K+D + K+ CL++ EK + E AK+ V LQ EI +L+K+L + EK I ADK YK++ + L NL EE LK + I+ E +++ + E K + +E++ +Q L+ E+ +LE +Y++L KE + + + KP + T + +E+E TFS + A+ E ++ + + K+ D+++ ++LQ ++ L QE +++ + + E+++ + + E+ + + E + E L K + +L +E+ L+K L ++S + + M +LT + + EE + R+ SQKEA + +L++++ +K + ++ +A +++ L+ QL Q + E L Q+LK L P+ R++ +Q+EI+R+ ENL L E+ ++ +LK+ LK FA ++ + E + N + + + + I+ V K K G+++ + +K+ I +L P + + P L YI+FM R D+ ++ ++ + L+ I ++K+ ++KR + E + LSN ++ +QYSG + F NT+ +H ++DL E+ ++L +L + ++Q +++ +++N+L Q + + +L HE I + + G + +++ + + + + L S ++ H + +I Q+ + Y++ A LN LL R D+C +SKG+QI+YN+S E W+R + L++SGA + L P+ +A QLLQ +D+DA+ +C MC L T Q+VK+LN + P + + R+S I I+ +++ R D P +L P+ PF + ++L IP L L
Sbjct: 1 MAASELYTKFARVWIPDPEEVWKSAELLKDYKPGDKVLLLHLEEGKDLEYRLDPKTGELPHLRNPDILVGENDLTALSYLHEPAVLHNLRVRFIDSKLIYTYCGIVLVAINPYEQLPIYGEDIINAYSGQNMGDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYFATVSGSA-------SEANVEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRIIGANMRTYLLEKSRVVFQAEEERNYHIFYQLCASAKLPEFKMLRLG---NADSFHYTKQGGSPMIEGVDDAKEMAHTRQACTLLGISESYQMGIFRILAGILHLGNVGFASRDSDSCTIPPKHEPLTIFCDLMGVDYEEMCHWLCHRKLATATETYIKPISKLQATNARDALAKHIYAKLFNWIVDHVNQALHSAVK-----------------QHSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKEQIPWTLIDFYDNQPCINLIESKLGILDLLDEECKMPKGTDDTWAQKLYNTHLNKCALFEKPRMSNKAFIIKHFADKVEYQCEGFLEKNKDTVFEEQIKVLKSSKFKMLPELFQDDEKAISPTSATSSGRTPLTRVPVKPTKGRPGQTAKEHKKTVGHQFRNSLHLLMETLNATTPHYVRCIKPNDFKFPFTFDEKRAVQQLRACGVLETIRISAAGFPSRWTYQEFFSRYRVLMKQKDVLG-DRKQTCKNVLEKLILDKDKYQFGKTKIFFRAGQVAYLEKLRADKLRAACIRIQKTIRGWLLRKRYLCMQRAAITVQRYVRGYQARCYAKFLRRTKAATTIQKYWRMYVVRRRYKIRRAATIVIQSYLRGYLTRNRYRKILREYKAVIIQKRVRGWLARTHYKRTMKAIVYLQCCFRRMMAKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLMEKLTNLEGVYNSETEKLRNDVERLQLSEEEAKVATGRVLSLQEEIAKLRKDLEQTRSEKKSIEERADK------YKQETDQLVSNLKEENTLLKQEKETLNHRIVEQAKEMTETMERKLVEETKQLELDLNDERLRYQNLLNEFSRLEERYDDL-KEEMTLMLNVPKPGHKRTDSTHSSNESEYTFSSEFAETEDIAPRTEEPIEKK---------------------VPLDMSLFLKLQKRVTELEQEKQLMQDELDRKEEQVFR-SKAKEEERPQIRGAELEYESL------KRQELESENKKLKNELNELRKALSEKSAPEVTAPGAPAYRVLMEQLTSVSEELDVRKEEVLILRSQLVSQKEAIQPKDDKNTMTDSTILLEDVQKMK-DKGEIAQAYIGLKETNRLLESQLQSQKRSHENEAEALRGEIQSLKEENNRQQQLLAQNLQLPPEARIEASLQHEITRLTNENLDLMEQLEKQDKTVRKLKKQLKVFAKKIGELEVGQMENISPGQIIDEPIRPVNIPRKEKDFQ--------GMLEYKREDEQKLVKNLILELKPRGVAVNLIP-GLPAYILFMCVRHADYLNDDQKVRSLLTSTINSIKKVLKKRGDDFETVSFWLSNTCRFLHCLKQYSGEEGFMKHNTSRQNEHCLTNFDLAEYRQVLSDLAIQIYQQLVR-VLENIL-QPMIVSGMLEHETIQGVSGVKPTGLRKRTSSIADEGTYTLDSILRQLNSFHSVMCQHGMDPELIKQVVKQMFYIVGAITLNNLLLRKDMCSWSKGMQIRYNVSQLEEWLRDKNLMNSGAKETLEPLIQAAQLLQVKKKTDDDAEAICSMCNALTTAQIVKVLNLYTPVNEFEERVSVSFIRTIQMRLR-DRKDSP---QLLMDAKHIFPVTFPFNPSSLALETIQIPASLGLG 1823
BLAST of Dach-2 vs. Ensembl Mouse
Match: Myo5a (myosin VA [Source:MGI Symbol;Acc:MGI:105976]) HSP 1 Score: 1095.49 bits (2832), Expect = 0.000e+0 Identity = 710/1930 (36.79%), Postives = 1084/1930 (56.17%), Query Frame = 2
Query: 47 MALYEMYSKGVKIWIPDEESVWIGATVLQFHKEKN-VIKIITDNGISKELNLSSKKCA-PFLRNPDILIGQKDLTYLSYLNEPEVLYNLQIRFCERREIYTYCGIVLVAINPYQELSIYGKEIINAYHSQNSVDLDPHIFAVAENAFRRMSSFGENQSIIVSGESGAGKTVSAKYTMRYFALVGGSKTKQSFNLTETQIERKVLLSNPILEAFGNAKTIRNDNSSRFGKYLEILFNPRNQVIGANMCTYLLEKSRVVFQNLGERNYHIFYQIVTHCQSEDELLMNTGLVNNVEMYDYLRYGESLEIDGVDDSHEFLITKNSFLQLGIDLNKFKTICEILAAILHLGNIRFRFHDATDSSIIENPELLKLIAGLLGCSIDQLKIWLCFRTISTFQETLHKPLSKAEAQYFRDAFVKTLYSNLFDWIVKQANKVLSTDVSINIKKKLKKTIVVNQEDKKKFIAVLDIYGFETFAENSFEQFCINFANEKLQLQFNLHVFKLEQEEYMNEGLEWTFIDYYNNQPCIDLIESRXXXXXXXXXXXXXXXXSDENWCCKIYSHHLNKSANFNKPKLSNMVFIIEHFAGPVEYKCAGFIEKNRDSVLEEQINLLKASDVQLIAELFRDSEIEIFDTNNXXXXXXXXXXXXXXXXXXQ--ENTRKMKKTVGSQFRNSLKSLMDALNKTNPHYVRCIKPNDLKLPFTFCPERAVQQLRACGVLETIRLSAAGFPSRWTYSDFYHRYYILMSNFNVKNHDFKAGSQKIVETLITVPDAFRFGNTKLFFRPGQVALLEKLRGHKIESSVTLIQSILRGSIERKKYLIIHKLTVQIQTYIRRKLAIEKATKLSQIRAVIIIQSFYRMYLARKLFVKMKCAVLAIEKWRRKIITTRLKQAYKKENCVIICQAIVRRFIQRRKFLKIQRGVILIQNHYRRRKAKETLKILKIEARSINHIKFVNKGLENKIIELTQKLDTKEKEM-CXXXXXX--------XXXXXXXXXXXXXXXAESAKIYQNTVQDLQTEIIQLKKELNREIVEKNKI--FADKELLEINYKKKINYL-ENLIEE---LKSSPSVIEPNIICNGDEAQQSICQD--EHQKFI-----NEQMDHQKLVREYEKLEMKYENLYKEFLFVKSSNQKPSINYDNQTSNDSETESTFSKDDADVESLSDKVDAKTTKEHXXXXXXXXXXLPNFISESISTAGDLAVVMQLQMNISSLSQENNRLKETVQQFEDELLKYEQCAEDSKGLVIHNEYDNELLSIIKDIKGMDEHGLKSRLIDEVANLKKKL-KQSNEDYQKLRLHIFDGSMSKLTGNLDHESINSEEEELKRA-FESQKEANRK------------MLKEIEGIKANNVDLKKALFQIRKDKEQLQVQLGKQHLMIRHGVEYL----QNLK---------------LTPKERLDKFVQNEISRILLENLKLQ----------------------------ERNDQIISETIELKRGLKYFAFRLQKYEGSLVPNPNKEEDLLQLIQNVIYHSKMKTIGKRECYSEIGLIDLNMSELSIFIKSFIFDLSP-SICLQYEPYHLVPYIIFMVTRKFDFYKEEDQMTNFLSKLIVALKRTIRKRRNYIEYLVMLLSNVFCLVNLXXXXXXXXXXXXLNTAEDIQHYFVHYDLNEFIRLLKELCVTLFQMILKTIVDNLLPQSLCIDAILVHEAI--IDFLSKDGTKYKSNIETQPKNTSFNVLTKNLQSVLEILKNHKIPQLIINQIFVHIAYLINAYCLNTLLFRTDLCYFSKGLQIKYNLSSFETWIRYQKLIDSGALQCLRPMTEAVQLLQTLIDSDEDAKFVCDMCEYLNTRQVVKILNNFNPRDGYGCRLSSGLIAKIETQMKIKRGDEPSESKLETPTVIEIPIDIPFIHNGVSLCRTIIPKPLYLS 5566
MA E+Y+K ++WIPD E VW A +L+ +K + V+ + + G E L K P LRNPDIL+G+ DLT LSYL+EP VL+NL++RF + + IYTYCGIVLVAINPY++L IYG++IINAY QN D+DPHIFAVAE A+++M+ NQSIIVSGESGAGKTVSAKY MRYFA V GS +E +E KVL SNPI+E+ GNAKT RNDNSSRFGKY+EI F+ R ++IGANM TYLLEKSRVVFQ ERNYHIFYQ+ + + ++ G N + + Y + G S I+GVDD+ E T+ + LGI + I ILA ILHLGN+ F D+ +I E L + L+G +++ WLC R ++T ET KP+SK +A RDA K +Y+ LF+WIV N+ L + V + FI VLDIYGFETF NSFEQFCIN+ANEKLQ QFN+HVFKLEQEEYM E + WT ID+Y+NQPCI+LIES+LG+LDLLDEECK+ KG+D+ W K+Y+ HLNK A F KP++SN FII+HFA VEY+C GF+EKN+D+V EEQI +LK+S +++ ELF+D E I T+ + + + + + + ++ KKTVG QFRNSL LM+ LN T PHYVRCIKPND K PFTF +RAVQQLRACGVLETIR+SAAGFPSRWTY +F+ RY +LM +V D K + ++E LI D ++FG TK+FFR GQVA LEKLR K+ ++ IQ +RG + RK+YL + + + +Q Y+R A A L + +A IQ ++RMY+ R+ + + A + I+ + R +T + +E +I Q VR ++ R + + + ++ +Q +RR AK LK LKIEARS+ K ++ G+ENKI++L +K+D + K+ CL++ EK + E AK+ V LQ EI +L+K+L + EK I ADK YK++ + L NL EE LK + I+ E +++ + E K + +E++ +Q L+ E+ +LE +Y++L KE + + + KP + T + +E+E TFS + A+ E ++ + + K+ D+++ ++LQ ++ L QE +++ + + E+++ + + E+ + + E + E L K + +L +E+ L+K L ++S + + M +LT + + EE + R+ SQKEA + +L++++ +K + ++ +A +++ L+ QL Q + E L Q+LK L P+ R++ +Q+EI+R+ ENL + E+ D+ + +LK+ LK FA ++ + E + N + + + + I+ V K K G+++ + +K+ I +L P + + P L YI+FM R D+ ++ ++ + L+ I ++K+ ++KR + E + LSN ++ +QYSG + F NT+ +H ++DL E+ ++L +L + ++Q +++ +++N+L Q + + +L HE I + + G + +++ + + + + L S ++ H + +I Q+ + Y++ A LN LL R D+C +SKG+QI+YN+S E W+R + L++SGA + L P+ +A QLLQ +D+DA+ +C MC L T Q+VK+LN + P + + R+S I I+ +++ R D P +L P+ PF + ++L IP L L
Sbjct: 1 MAASELYTKFARVWIPDPEEVWKSAELLKDYKPGDKVLLLHLEEGKDLEYRLDPKTGELPHLRNPDILVGENDLTALSYLHEPAVLHNLRVRFIDSKLIYTYCGIVLVAINPYEQLPIYGEDIINAYSGQNMGDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYFATVSGSA-------SEANVEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRIIGANMRTYLLEKSRVVFQAEEERNYHIFYQLCASAKLPEFKMLRLG---NADSFHYTKQGGSPMIEGVDDAKEMAHTRQACTLLGISESYQMGIFRILAGILHLGNVGFASRDSDSCTIPPKHEPLTIFCDLMGVDYEEMCHWLCHRKLATATETYIKPISKLQATNARDALAKHIYAKLFNWIVDHVNQALHSAVK-----------------QHSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKEQIPWTLIDFYDNQPCINLIESKLGILDLLDEECKMPKGTDDTWAQKLYNTHLNKCALFEKPRMSNKAFIIKHFADKVEYQCEGFLEKNKDTVFEEQIKVLKSSKFKMLPELFQDDEKAISPTSATSSGRTPLTRVPVKPTKGRPGQTAKEHKKTVGHQFRNSLHLLMETLNATTPHYVRCIKPNDFKFPFTFDEKRAVQQLRACGVLETIRISAAGFPSRWTYQEFFSRYRVLMKQKDVLG-DRKQTCKNVLEKLILDKDKYQFGKTKIFFRAGQVAYLEKLRADKLRAACIRIQKTIRGWLLRKRYLCMQRAAITVQRYVRGYQARCYAKFLRRTKAATTIQKYWRMYVVRRRYKIRRAATIVIQSYLRGYLTRNRYRKILREYKAVIIQKRVRGWLARTHYKRTMKAIVYLQCCFRRMMAKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLMEKLTNLEGVYNSETEKLRNDVERLQLSEEEAKVATGRVLSLQEEIAKLRKDLEQTRSEKKSIEERADK------YKQETDQLVSNLKEENTLLKQEKETLNHRIVEQAKEMTETMERKLVEETKQLELDLNDERLRYQNLLNEFSRLEERYDDL-KEEMTLMLNVPKPGHKRTDSTHSSNESEYTFSSEFAETEDIAPRTEEPIEKK---------------------VPLDMSLFLKLQKRVTELEQEKQLMQDELDRKEEQVFR-SKAKEEERPQIRGAELEYESL------KRQELESENKKLKNELNELRKALSEKSAPEVTAPGAPAYRVLMEQLTSVSEELDVRKEEVLILRSQLVSQKEAIQPKDDKNTMTDSTILLEDVQKMK-DKGEIAQAYIGLKETNRLLESQLQSQKRSHENEAEALRGEIQSLKEENNRQQQLLAQNLQLPPEARIEASLQHEITRLTNENLYFEELYADDPKKYQSYRISLYKRMIDLMEQLEKQDKTVR---KLKKQLKVFAKKIGELEVGQMENISPGQIIDEPIRPVNIPRKEKDFQ--------GMLEYKREDEQKLVKNLILELKPRGVAVNLIP-GLPAYILFMCVRHADYLNDDQKVRSLLTSTINSIKKVLKKRGDDFETVSFWLSNTCRFLHCLKQYSGEEGFMKHNTSRQNEHCLTNFDLAEYRQVLSDLAIQIYQQLVR-VLENIL-QPMIVSGMLEHETIQGVSGVKPTGLRKRTSSIADEGTYTLDSILRQLNSFHSVMCQHGMDPELIKQVVKQMFYIVGAITLNNLLLRKDMCSWSKGMQIRYNVSQLEEWLRDKNLMNSGAKETLEPLIQAAQLLQVKKKTDDDAEAICSMCNALTTAQIVKVLNLYTPVNEFEERVSVSFIRTIQMRLR-DRKDSP---QLLMDAKHIFPVTFPFNPSSLALETIQIPASLGLG 1848
BLAST of Dach-2 vs. Ensembl Mouse
Match: Myo5b (myosin VB [Source:MGI Symbol;Acc:MGI:106598]) HSP 1 Score: 1094.34 bits (2829), Expect = 0.000e+0 Identity = 713/1902 (37.49%), Postives = 1081/1902 (56.83%), Query Frame = 2
Query: 47 MALYEMYSKGVKIWIPDEESVWIGATVLQFHKEKN---VIKIITDNGISKELNLSSKKCAPFLRNPDILIGQKDLTYLSYLNEPEVLYNLQIRFCERREIYTYCGIVLVAINPYQELSIYGKEIINAYHSQNSVDLDPHIFAVAENAFRRMSSFGENQSIIVSGESGAGKTVSAKYTMRYFALVGGSKTKQSFNLTETQIERKVLLSNPILEAFGNAKTIRNDNSSRFGKYLEILFNPRNQVIGANMCTYLLEKSRVVFQNLGERNYHIFYQIVTHCQSEDELLMNTGLVNNVEMYDYLRYGESLEIDGVDDSHEFLITKNSFLQLGIDLNKFKTICEILAAILHLGNIRFRFHDATDS-SIIENPELLKLIAGLLGCSIDQLKIWLCFRTISTFQETLHKPLSKAEAQYFRDAFVKTLYSNLFDWIVKQANKVLSTDVSINIKKKLKKTIVVNQEDKKKFIAVLDIYGFETFAENSFEQFCINFANEKLQLQFNLHVFKLEQEEYMNEGLEWTFIDYYNNQPCIDLIESRXXXXXXXXXXXXXXXXSDENWCCKIYSHHLNKSANFNKPKLSNMVFIIEHFAGPVEYKCAGFIEKNRDSVLEEQINLLKASDVQLIAELFRDSEIEIFDTNNXXXXXXXXXXXXXXXXXXQENTRKMKKTVGSQFRNSLKSLMDALNKTNPHYVRCIKPNDLKLPFTFCPERAVQQLRACGVLETIRLSAAGFPSRWTYSDFYHRYYILMSNFNVKNHDFKAGSQKIVETLITVPDAFRFGNTKLFFRPGQVALLEKLRGHKIESSVTLIQSILRGSIERKKYLIIHKLTVQIQTYIRRKLAIEKATKLSQIRAVIIIQSFYRMYLARKLFVKMKCAVLAIEKWRRKIITTRLKQAYKKENCVIICQAIVRRFIQRRKFLKIQRGVILIQNHYRRRKAKETLKILKIEARSINHIKFVNKGLENKIIELTQKLDTKEKEMCXXXXXXXXXXXXXXXXXXXXXAESAKIYQNTVQD----LQTEIIQLKKELNREIVEKNKIFAD---KELLEINYKKKINYLENLIEELKSSPSVIEPNIICNGD-EAQQSICQDE---HQKFINEQMDHQKLVREYEKLEMKYENLYKEFLFVKSSNQKPSINYDNQTSNDSETESTFSKDDADVESLSDKVDAKTTKEHXXXXXXXXXXLPNFISESISTAGDLAVVMQLQMNISSLSQENNRLKETVQQFEDELLKYEQCAEDSKGLVIHNEYD----------------------NELLSIIKDIKGMDEHGLKSRLIDEVANLKKKLKQSNEDYQK-------LRLHIFDGSMSKLTGNLDHESINS-----------EEEELKRAFESQKEANRKMLKEIEGIKANNVDLKKALFQIRKDKEQLQVQLGKQHLMIRHGVEYLQNLKLTPKERLDKFVQNEISRILLENLKLQERNDQIISETIELKRGLKYFAFRLQKYEG--SLVPNPNKEEDLLQLIQNVIYHSKMKTIGKRECYSEIGLIDLNMSELSIFIKSFIFDLSPSICLQYEPYHLVPYIIFMVTRKFDFYKEEDQMTNFLSKLIVALKRTIRKRRNYIEYLVMLLSNVFCLVNLXXXXXXXXXXXXLNTAEDIQHYFVHYDLNEFIRLLKELCVTLFQMILKTIVDNLLPQSLCIDAILVHEAI--IDFLSKDGTKYKSNIETQPKNT-SFNVLTKNLQSVLEILKNHKIPQLIINQIFVHIAYLINAYCLNTLLFRTDLCYFSKGLQIKYNLSSFETWIRYQKLIDSGALQCLRPMTEAVQLLQTLIDSDEDAKFVCDMCEYLNTRQVVKILNNFNPRDGYGCRLSSGLIAKIETQMKIKRGDEPSESKLETPTVIEIPIDIPFIHNGVSLCRTIIPKPLYLSCL 5572
M+ E+Y++ ++WIPD + VW A + + +KE + +++ D + +++ + + PFLRNPDIL+G+ DLT LS+L+EP VL+NL++RF E IYTYCGIVLVAINPY++L IYG+++I AY QN D+DPHIFAVAE A+++M+ +NQSIIVSGESGAGKTVSAKY MRYFA VGGS + +T IE KVL S+PI+EA GNAKT RNDNSSRFGK++EI F+ + +IGANM TYLLEKSRVVFQ ERNYHIFYQ+ C + + E + Y +G + I+GV+D+ +F T+ + LG+ + +I +I+A+ILHLG++ + DS SI E L LLG Q++ WLC R + T ET K +S + RDA K +Y+ LF WIV+ NK L T + + FI VLDIYGFETF NSFEQFCIN+ANEKLQ QFN HVFKLEQEEYM E + WT ID+Y+NQPCIDLIE++LG+LDLLDEECK+ KG+D+NW K+Y H N S +F KP++SN FI+ HFA VEY GF+EKNRD+V EEQIN+LKAS L+A+LF D + TN +K + S K + +S + + ++ KK+VG QFR SL LM+ LN T PHYVRCIKPND KLPF F P+RAVQQLRACGVLETIR+SAAG+PSRWTY DF++RY +LM + N D K + ++E+LI PD F+FG TK+FFR GQVA LEKLR K + +IQ +RG ++R KY + T+ +Q + R LA A L + RA I+ Q YRM AR+ + ++ A + I+ + R + R + E+ I Q R ++ R++FL+ + I+IQ +RR KA++ LK LKIEARS H+K +N G+ENK+++L +K+D + KE + QL + ++ + E A QN D LQ E+ L+ EL + E+ ++ D KE E+ +K++ LE+ LK + I+C E+ QS ++ ++ E+ +Q LV+EY +LE +YENL E Q P + SN S ES + + D DA E + A D+ V ++LQ + L QE +L+ +++ + + K Q + + GL + + D NEL + D + M ++ S D + L +LK +NE+ + LR I + +L+G +IN+ ++E+ A+ + NR + +++ A +++ ++ + ++ E L+ ++ KQ + Q L L+P+ +++ VQ EISR+ ENL +E +++ +LK+ LK + ++Q E +L + + +L + + T+ ++E + G+++ + + ++ I++ + DL P + P L YI++M R D+ ++ ++ + LS I +K+ ++K + E LSN ++ +QYSG + F NTA+ +H ++DL E+ ++L +L + ++Q ++K I + LL Q + + A+L +E+I + + G + +S+ +N+ + + + S +L + + II Q+F + Y+INA LN LL R D C +S G+Q++YN+S E W+R + L SGA+Q + P+ +A QLLQ + EDA+ +C +C L+T+Q+VKILN + P + + R++ I I+ Q++ +R D P + L++ V P+ P+ + +++ IP L L L
Sbjct: 1 MSYSELYTRYTRVWIPDPDEVWRSAELTKDYKEGDKSLQLRLEDDTILEYPVDVQNNQ-VPFLRNPDILVGENDLTALSHLHEPAVLHNLKVRFLESNHIYTYCGIVLVAINPYEQLPIYGQDVIYAYSGQNMGDMDPHIFAVAEEAYKQMARDEKNQSIIVSGESGAGKTVSAKYAMRYFATVGGSAS-------DTNIEEKVLASSPIMEAIGNAKTTRNDNSSRFGKFIEIGFDKKYHIIGANMRTYLLEKSRVVFQADDERNYHIFYQL---CAAASLPEFKELALTCAEDFFYTAHGGNTTIEGVNDADDFEKTRQALTLLGVRDSHQISIFKIIASILHLGSVEIQSERDGDSCSISPQDEHLSNFCSLLGIEHSQMEHWLCHRKLVTTSETYVKTMSLQQVVNARDALAKHIYAQLFSWIVEHINKALHTSLK-----------------QHSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNSHVFKLEQEEYMKEQIPWTLIDFYDNQPCIDLIEAKLGILDLLDEECKVPKGTDQNWAQKLYERHSN-SQHFQKPRMSNTAFIVNHFADKVEYLSDGFLEKNRDTVYEEQINILKASKFPLVADLFHDDKDSAPATNTAKNRSSSKINVRSSRPLIKVPNKEHKKSVGYQFRTSLNLLMETLNATTPHYVRCIKPNDEKLPFHFDPKRAVQQLRACGVLETIRISAAGYPSRWTYHDFFNRYRVLMKKRELTNTDKKNICKSVLESLIKDPDKFQFGRTKIFFRAGQVAYLEKLRADKFREATIMIQKSVRGWLQRVKYRRLRAATLSLQRFCRGYLARRLAEHLRRTRAAIVFQKQYRMLKARRAYRRVCRATVIIQSFTRAMFVRRNYRQVLMEHKATIIQKYARGWMARKRFLRERDAAIVIQCAFRRLKARQELKALKIEARSAEHLKRLNVGMENKVVQLQRKIDDQNKEFKTLSEQLSAVTSSHAVEVEKLKKELAHYQQNQEADTSLQLQEEVQSLRTELQKAHSER-RVLEDAHNKENGEL--RKRVADLEHENALLKDEKEYLNNQILCQSKAESSQSSVEENLLMKKELEEERSRYQNLVKEYSQLEQRYENLRDE--------QTPG--HRKNPSNQSSLESDSNYPSISTSEIGDTEDALQQVEEIGIE---------------KAAMDMTVFLKLQKRVRELEQERKKLQAQLEKGQQD-SKKGQVEQQNNGLDVDQDADIAYNSLKRQELESENKKLKNDLNELRKAVAD-QAMQDNSTHSS-PDSYSLLLNQLKLANEELEVRKEEVLILRTQIMNADQRRLSGKNMEPNINARTSWPNSEKHVDQEDAIEAYHGVCQTNRLLEAQLQ---AQSLEHEEEVEHLKAQVEALKEEMDKQQQT------FCQTLLLSPEAQVEFGVQQEISRLTNENLDFKELVEKLEKNERKLKKQLKIYMKKVQDLEAAQALAQSDRRHHELTRQV----------TVQRKEKDFQ-GMLEYHKEDEALLIRNLVTDLKPQMLSGTVPC-LPAYILYMCIRHADYTNDDLKVHSLLSSTINGIKKVLKKHNDDFEMTSFWLSNTCRFLHCLKQYSGDEGFMTQNTAKQNEHCLKNFDLTEYRQVLSDLSIQIYQQLIK-IAEGLL-QPMIVSAMLENESIQGLSGVRPTGYRKRSSSMVDGENSYCLEAIVRQMNSFHTVLCDQGLDPEIILQVFKQLFYMINAVTLNNLLLRKDACSWSTGMQLRYNISQLEEWLRGKNLHQSGAVQTMEPLIQAAQLLQLKKKTHEDAEAICSLCTSLSTQQIVKILNLYTPLNEFEERVTVSFIRTIQAQLQ-ERND-PQQLLLDSKHV--FPVLFPYNPSALTMDSIHIPACLNLEFL 1815
BLAST of Dach-2 vs. Ensembl Mouse
Match: Myo5b (myosin VB [Source:MGI Symbol;Acc:MGI:106598]) HSP 1 Score: 1087.4 bits (2811), Expect = 0.000e+0 Identity = 717/1921 (37.32%), Postives = 1078/1921 (56.12%), Query Frame = 2
Query: 47 MALYEMYSKGVKIWIPDEESVWIGATVLQFHKEKN---VIKIITDNGISKELNLSSKKCAPFLRNPDILIGQKDLTYLSYLNEPEVLYNLQIRFCERREIYTYCGIVLVAINPYQELSIYGKEIINAYHSQNSVDLDPHIFAVAENAFRRMSSFGENQSIIVSGESGAGKTVSAKYTMRYFALVGGSKTKQSFNLTETQIERKVLLSNPILEAFGNAKTIRNDNSSRFGKYLEILFNPRNQVIGANMCTYLLEKSRVVFQNLGERNYHIFYQIVTHCQSEDELLMNTGLVNNVEMYDYLRYGESLEIDGVDDSHEFLITKNSFLQLGIDLNKFKTICEILAAILHLGNIRFRFHDATDS-SIIENPELLKLIAGLLGCSIDQLKIWLCFRTISTFQETLHKPLSKAEAQYFRDAFVKTLYSNLFDWIVKQANKVLSTDVSINIKKKLKKTIVVNQEDKKKFIAVLDIYGFETFAENSFEQFCINFANEKLQLQFNLHVFKLEQEEYMNEGLEWTFIDYYNNQPCIDLIESRXXXXXXXXXXXXXXXXSDENWCCKIYSHHLNKSANFNKPKLSNMVFIIEHFAGPVEYKCAGFIEKNRDSVLEEQINLLKASDVQLIAELFRDSEIEIFDTNNXXXXXXXXXXXXXXXXXXQENTRKMKKTVGSQFRNSLKSLMDALNKTNPHYVRCIKPNDLKLPFTFCPERAVQQLRACGVLETIRLSAAGFPSRWTYSDFYHRYYILMSNFNVKNHDFKAGSQKIVETLITVPDAFRFGNTKLFFRPGQVALLEKLRGHKIESSVTLIQSILRGSIERKKYLIIHKLTVQIQTYIRRKLAIEKATKLSQIRAVIIIQSFYRMYLARKLFVKMKCAVLAIEKWRRKIITTRLKQAYKKENCVIICQAIVRRFIQRRKFLKIQRGVILIQNHYRRRKAKETLKILKIEARSINHIKFVNKGLENKIIELTQKLDTKEKEMCXXXXXXXXXXXXXXXXXXXXXAESAKIYQNTVQD----LQTEIIQLKKELNREIVEKNKIFAD---KELLEINYKKKINYLENLIEELKSSPSVIEPNIICNGD-EAQQSICQDE---HQKFINEQMDHQKLVREYEKLEMKYENLYKEFLFVKSSNQKPSINYDNQTSNDSETESTFSKDDADVESLSDKVDAKTTKEHXXXXXXXXXXLPNFISESISTAGDLAVVMQLQMNISSLSQENNRLKETVQQFEDELLKYEQCAEDSKGLVIHNEYD----------------------NELLSIIKDIKGMDEHGLKSRLIDEVANLKKKLKQSNEDYQK-------LRLHIFDGSMSKLTGNLDHESINS-----------EEEELKRAFESQKEANRKMLKEIEGIKANNVDLKKALFQIRKDKEQLQVQLGKQHL-------------------MIRHGVEYLQNLKLTPKERLDKFVQNEISRILLENLKLQERNDQIISETIELKRGLKYFAFRLQKYEG--SLVPNPNKEEDLLQLIQNVIYHSKMKTIGKRECYSEIGLIDLNMSELSIFIKSFIFDLSPSICLQYEPYHLVPYIIFMVTRKFDFYKEEDQMTNFLSKLIVALKRTIRKRRNYIEYLVMLLSNVFCLVNLXXXXXXXXXXXXLNTAEDIQHYFVHYDLNEFIRLLKELCVTLFQMILKTIVDNLLPQSLCIDAILVHEAI--IDFLSKDGTKYKSNIETQPKNT-SFNVLTKNLQSVLEILKNHKIPQLIINQIFVHIAYLINAYCLNTLLFRTDLCYFSKGLQIKYNLSSFETWIRYQKLIDSGALQCLRPMTEAVQLLQTLIDSDEDAKFVCDMCEYLNTRQVVKILNNFNPRDGYGCRLSSGLIAKIETQMKIKRGDEPSESKLETPTVIEIPIDIPFIHNGVSLCRTIIPKPLYLSCL 5572
M+ E+Y++ ++WIPD + VW A + + +KE + +++ D + +++ + + PFLRNPDIL+G+ DLT LS+L+EP VL+NL++RF E IYTYCGIVLVAINPY++L IYG+++I AY QN D+DPHIFAVAE A+++M+ +NQSIIVSGESGAGKTVSAKY MRYFA VGGS + +T IE KVL S+PI+EA GNAKT RNDNSSRFGK++EI F+ + +IGANM TYLLEKSRVVFQ ERNYHIFYQ+ C + + E + Y +G + I+GV+D+ +F T+ + LG+ + +I +I+A+ILHLG++ + DS SI E L LLG Q++ WLC R + T ET K +S + RDA K +Y+ LF WIV+ NK L T + + FI VLDIYGFETF NSFEQFCIN+ANEKLQ QFN HVFKLEQEEYM E + WT ID+Y+NQPCIDLIE++LG+LDLLDEECK+ KG+D+NW K+Y H N S +F KP++SN FI+ HFA VEY GF+EKNRD+V EEQIN+LKAS L+A+LF D + TN +K + S K + +S + + ++ KK+VG QFR SL LM+ LN T PHYVRCIKPND KLPF F P+RAVQQLRACGVLETIR+SAAG+PSRWTY DF++RY +LM + N D K + ++E+LI PD F+FG TK+FFR GQVA LEKLR K + +IQ +RG ++R KY + T+ +Q + R LA A L + RA I+ Q YRM AR+ + ++ A + I+ + R + R + E+ I Q R ++ R++FL+ + I+IQ +RR KA++ LK LKIEARS H+K +N G+ENK+++L +K+D + KE + QL + ++ + E A QN D LQ E+ L+ EL + E+ ++ D KE E+ +K++ LE+ LK + I+C E+ QS ++ ++ E+ +Q LV+EY +LE +YENL E Q P + SN S ES + + D DA E + A D+ V ++LQ + L QE +L+ +++ + + K Q + + GL + + D NEL + D + M ++ S D + L +LK +NE+ + LR I + +L+G +IN+ ++E+ A+ + N + E G + +L A +++ L+ QL Q L M + + Q L L+P+ +++ VQ EISR+ ENL +E +++ +LK+ LK + ++Q E +L + + +L + + T+ ++E + G+++ + + ++ I++ + DL P + P L YI++M R D+ ++ ++ + LS I +K+ ++K + E LSN ++ +QYSG + F NTA+ +H ++DL E+ ++L +L + ++Q ++K I + LL Q + + A+L +E+I + + G + +S+ +N+ + + + S +L + + II Q+F + Y+INA LN LL R D C +S G+Q++YN+S E W+R + L SGA+Q + P+ +A QLLQ + EDA+ +C +C L+T+Q+VKILN + P + + R++ I I+ Q++ +R D P + L++ V P+ P+ + +++ IP L L L
Sbjct: 1 MSYSELYTRYTRVWIPDPDEVWRSAELTKDYKEGDKSLQLRLEDDTILEYPVDVQNNQV-PFLRNPDILVGENDLTALSHLHEPAVLHNLKVRFLESNHIYTYCGIVLVAINPYEQLPIYGQDVIYAYSGQNMGDMDPHIFAVAEEAYKQMARDEKNQSIIVSGESGAGKTVSAKYAMRYFATVGGSAS-------DTNIEEKVLASSPIMEAIGNAKTTRNDNSSRFGKFIEIGFDKKYHIIGANMRTYLLEKSRVVFQADDERNYHIFYQL---CAAASLPEFKELALTCAEDFFYTAHGGNTTIEGVNDADDFEKTRQALTLLGVRDSHQISIFKIIASILHLGSVEIQSERDGDSCSISPQDEHLSNFCSLLGIEHSQMEHWLCHRKLVTTSETYVKTMSLQQVVNARDALAKHIYAQLFSWIVEHINKALHTSLK-----------------QHSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNSHVFKLEQEEYMKEQIPWTLIDFYDNQPCIDLIEAKLGILDLLDEECKVPKGTDQNWAQKLYERHSN-SQHFQKPRMSNTAFIVNHFADKVEYLSDGFLEKNRDTVYEEQINILKASKFPLVADLFHDDKDSAPATNTAKNRSSSKINVRSSRPLIKVPNKEHKKSVGYQFRTSLNLLMETLNATTPHYVRCIKPNDEKLPFHFDPKRAVQQLRACGVLETIRISAAGYPSRWTYHDFFNRYRVLMKKRELTNTDKKNICKSVLESLIKDPDKFQFGRTKIFFRAGQVAYLEKLRADKFREATIMIQKSVRGWLQRVKYRRLRAATLSLQRFCRGYLARRLAEHLRRTRAAIVFQKQYRMLKARRAYRRVCRATVIIQSFTRAMFVRRNYRQVLMEHKATIIQKYARGWMARKRFLRERDAAIVIQCAFRRLKARQELKALKIEARSAEHLKRLNVGMENKVVQLQRKIDDQNKEFKTLSEQLSAVTSSHAVEVEKLKKELAHYQQNQEADTSLQLQEEVQSLRTELQKAHSER-RVLEDAHNKENGEL--RKRVADLEHENALLKDEKEYLNNQILCQSKAESSQSSVEENLLMKKELEEERSRYQNLVKEYSQLEQRYENLRDE--------QTPG--HRKNPSNQSSLESDSNYPSISTSEIGDTEDALQQVEEIGIE---------------KAAMDMTVFLKLQKRVRELEQERKKLQAQLEKGQQD-SKKGQVEQQNNGLDVDQDADIAYNSLKRQELESENKKLKNDLNELRKAVAD-QAMQDNSTHSS-PDSYSLLLNQLKLANEELEVRKEEVLILRTQIMNADQRRLSGKNMEPNINARTSWPNSEKHVDQEDAIEAYHGVCQTNSQT--EDWGYLNEDGELGLAYQGLKQVARLLEAQLQAQSLEHEEEVEHLKAQVEALKEEMDKQQQTFCQTLLLSPEAQVEFGVQQEISRLTNENLDFKELVEKLEKNERKLKKQLKIYMKKVQDLEAAQALAQSDRRHHELTRQV----------TVQRKEKDFQ-GMLEYHKEDEALLIRNLVTDLKPQMLSGTVPC-LPAYILYMCIRHADYTNDDLKVHSLLSSTINGIKKVLKKHNDDFEMTSFWLSNTCRFLHCLKQYSGDEGFMTQNTAKQNEHCLKNFDLTEYRQVLSDLSIQIYQQLIK-IAEGLL-QPMIVSAMLENESIQGLSGVRPTGYRKRSSSMVDGENSYCLEAIVRQMNSFHTVLCDQGLDPEIILQVFKQLFYMINAVTLNNLLLRKDACSWSTGMQLRYNISQLEEWLRGKNLHQSGAVQTMEPLIQAAQLLQLKKKTHEDAEAICSLCTSLSTQQIVKILNLYTPLNEFEERVTVSFIRTIQAQLQ-ERND-PQQLLLDSKHV--FPVLFPYNPSALTMDSIHIPACLNLEFL 1841
BLAST of Dach-2 vs. Ensembl Mouse
Match: Myo5a (myosin VA [Source:MGI Symbol;Acc:MGI:105976]) HSP 1 Score: 932.939 bits (2410), Expect = 0.000e+0 Identity = 542/1241 (43.67%), Postives = 760/1241 (61.24%), Query Frame = 2
Query: 47 MALYEMYSKGVKIWIPDEESVWIGATVLQFHKEKN-VIKIITDNGISKELNLSSKKCA-PFLRNPDILIGQKDLTYLSYLNEPEVLYNLQIRFCERREIYTYCGIVLVAINPYQELSIYGKEIINAYHSQNSVDLDPHIFAVAENAFRRMSSFGENQSIIVSGESGAGKTVSAKYTMRYFALVGGSKTKQSFNLTETQIERKVLLSNPILEAFGNAKTIRNDNSSRFGKYLEILFNPRNQVIGANMCTYLLEKSRVVFQNLGERNYHIFYQIVTHCQSEDELLMNTGLVNNVEMYDYLRYGESLEIDGVDDSHEFLITKNSFLQLGIDLNKFKTICEILAAILHLGNIRFRFHDATDSSIIENPELLKLIAGLLGCSIDQLKIWLCFRTISTFQETLHKPLSKAEAQYFRDAFVKTLYSNLFDWIVKQANKVLSTDVSINIKKKLKKTIVVNQEDKKKFIAVLDIYGFETFAENSFEQFCINFANEKLQLQFNLHVFKLEQEEYMNEGLEWTFIDYYNNQPCIDLIESRXXXXXXXXXXXXXXXXSDENWCCKIYSHHLNKSANFNKPKLSNMVFIIEHFAGPVEYKCAGFIEKNRDSVLEEQINLLKASDVQLIAELFRDSEIEIFDTNNXXXXXXXXXXXXXXXXXXQ--ENTRKMKKTVGSQFRNSLKSLMDALNKTNPHYVRCIKPNDLKLPFTFCPERAVQQLRACGVLETIRLSAAGFPSRWTYSDFYHRYYILMSNFNVKNHDFKAGSQKIVETLITVPDAFRFGNTKLFFRPGQVALLEKLRGHKIESSVTLIQSILRGSIERKKYLIIHKLTVQIQTYIRRKLAIEKATKLSQIRAVIIIQSFYRMYLARKLFVKMKCAVLAIEKWRRKIITTRLKQAYKKENCVIICQAIVRRFIQRRKFLKIQRGVILIQNHYRRRKAKETLKILKIEARSINHIKFVNKGLENKIIELTQKLDTKEKEM-CXXXXXX--------XXXXXXXXXXXXXXXAESAKIYQNTVQDLQTEIIQLKKELNREIVEKNKI--FADKELLEINYKKKINYL-ENLIEE---LKSSPSVIEPNIICNGDEAQQSICQD--EHQKFI-----NEQMDHQKLVREYEKLEMKYENLYKEFLFVKSSNQKPSINYDNQTSNDSETESTFSKDDADVESLSDKVDAKTTKEHXXXXXXXXXXLPNFISESISTAGDLAVVMQLQMNISSLSQENNRLKETVQQFEDELLK 3691
MA E+Y+K ++WIPD E VW A +L+ +K + V+ + + G E L K P LRNPDIL+G+ DLT LSYL+EP VL+NL++RF + + IYTYCGIVLVAINPY++L IYG++IINAY QN D+DPHIFAVAE A+++M+ NQSIIVSGESGAGKTVSAKY MRYFA V GS +E +E KVL SNPI+E+ GNAKT RNDNSSRFGKY+EI F+ R ++IGANM TYLLEKSRVVFQ ERNYHIFYQ+ + + ++ G N + + Y + G S I+GVDD+ E T+ + LGI + I ILA ILHLGN+ F D+ +I E L + L+G +++ WLC R ++T ET KP+SK +A RDA K +Y+ LF+WIV N+ L + V + FI VLDIYGFETF NSFEQFCIN+ANEKLQ QFN+HVFKLEQEEYM E + WT ID+Y+NQPCI+LIES+LG+LDLLDEECK+ KG+D+ W K+Y+ HLNK A F KP++SN FII+HFA VEY+C GF+EKN+D+V EEQI +LK+S +++ ELF+D E I T+ + + + + + + ++ KKTVG QFRNSL LM+ LN T PHYVRCIKPND K PFTF +RAVQQLRACGVLETIR+SAAGFPSRWTY +F+ RY +LM +V D K + ++E LI D ++FG TK+FFR GQVA LEKLR K+ ++ IQ +RG + RK+YL + + + +Q Y+R A A L + +A IQ ++RMY+ R+ + + A + I+ + R +T + +E +I Q VR ++ R + + + ++ +Q +RR AK LK LKIEARS+ K ++ G+ENKI++L +K+D + K+ CL++ EK + E AK+ V LQ EI +L+K+L + EK I ADK YK++ + L NL EE LK + I+ E +++ + E K + +E++ +Q L+ E+ +LE +Y++L KE + + + KP + T + +E+E TFS + A+ E ++ + + K+ D+++ ++LQ ++ L QE +++ + + E+++ +
Sbjct: 1 MAASELYTKFARVWIPDPEEVWKSAELLKDYKPGDKVLLLHLEEGKDLEYRLDPKTGELPHLRNPDILVGENDLTALSYLHEPAVLHNLRVRFIDSKLIYTYCGIVLVAINPYEQLPIYGEDIINAYSGQNMGDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYFATVSGSA-------SEANVEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRIIGANMRTYLLEKSRVVFQAEEERNYHIFYQLCASAKLPEFKMLRLG---NADSFHYTKQGGSPMIEGVDDAKEMAHTRQACTLLGISESYQMGIFRILAGILHLGNVGFASRDSDSCTIPPKHEPLTIFCDLMGVDYEEMCHWLCHRKLATATETYIKPISKLQATNARDALAKHIYAKLFNWIVDHVNQALHSAVK-----------------QHSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKEQIPWTLIDFYDNQPCINLIESKLGILDLLDEECKMPKGTDDTWAQKLYNTHLNKCALFEKPRMSNKAFIIKHFADKVEYQCEGFLEKNKDTVFEEQIKVLKSSKFKMLPELFQDDEKAISPTSATSSGRTPLTRVPVKPTKGRPGQTAKEHKKTVGHQFRNSLHLLMETLNATTPHYVRCIKPNDFKFPFTFDEKRAVQQLRACGVLETIRISAAGFPSRWTYQEFFSRYRVLMKQKDVLG-DRKQTCKNVLEKLILDKDKYQFGKTKIFFRAGQVAYLEKLRADKLRAACIRIQKTIRGWLLRKRYLCMQRAAITVQRYVRGYQARCYAKFLRRTKAATTIQKYWRMYVVRRRYKIRRAATIVIQSYLRGYLTRNRYRKILREYKAVIIQKRVRGWLARTHYKRTMKAIVYLQCCFRRMMAKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLMEKLTNLEGVYNSETEKLRNDVERLQLSEEEAKVATGRVLSLQEEIAKLRKDLEQTRSEKKSIEERADK------YKQETDQLVSNLKEENTLLKQEKETLNHRIVEQAKEMTETMERKLVEETKQLELDLNDERLRYQNLLNEFSRLEERYDDL-KEEMTLMLNVPKPGHKRTDSTHSSNESEYTFSSEFAETEDIAPRTEEPIEKK---------------------VPLDMSLFLKLQKRVTELEQEKQLMQDELDRKEEQVFR 1185
BLAST of Dach-2 vs. UniProt/SwissProt
Match: sp|Q02440|MYO5A_CHICK (Unconventional myosin-Va OS=Gallus gallus OX=9031 GN=MYO5A PE=1 SV=1) HSP 1 Score: 1118.22 bits (2891), Expect = 0.000e+0 Identity = 730/1911 (38.20%), Postives = 1089/1911 (56.99%), Query Frame = 2
Query: 47 MALYEMYSKGVKIWIPDEESVWIGATVLQFHKEKN-VIKIITDNGISKELNLSSK-KCAPFLRNPDILIGQKDLTYLSYLNEPEVLYNLQIRFCERREIYTYCGIVLVAINPYQELSIYGKEIINAYHSQNSVDLDPHIFAVAENAFRRMSSFGENQSIIVSGESGAGKTVSAKYTMRYFALVGGSKTKQSFNLTETQIERKVLLSNPILEAFGNAKTIRNDNSSRFGKYLEILFNPRNQVIGANMCTYLLEKSRVVFQNLGERNYHIFYQIVTHCQSEDELLMNTGLVNNVEMYDYLRYGESLEIDGVDDSHEFLITKNSFLQLGIDLNKFKTICEILAAILHLGNIRFRFHDATDSSIIENPELLKLIAGLLGCSIDQLKIWLCFRTISTFQETLHKPLSKAEAQYFRDAFVKTLYSNLFDWIVKQANKVLSTDVSINIKKKLKKTIVVNQEDKKKFIAVLDIYGFETFAENSFEQFCINFANEKLQLQFNLHVFKLEQEEYMNEGLEWTFIDYYNNQPCIDLIESRXXXXXXXXXXXXXXXXSDENWCCKIYSHHLNKSANFNKPKLSNMVFIIEHFAGPVEYKCAGFIEKNRDSVLEEQINLLKAS-DVQLIAELFRDSEIEIFDTNNXXXXXXXXXXXXXXXXXXQ--ENTRKMKKTVGSQFRNSLKSLMDALNKTNPHYVRCIKPNDLKLPFTFCPERAVQQLRACGVLETIRLSAAGFPSRWTYSDFYHRYYILMSNFNVKNHDFKAGSQKIVETLITVPDAFRFGNTKLFFRPGQVALLEKLRGHKIESSVTLIQSILRGSIERKKYLIIHKLTVQIQTYIRRKLAIEKATKLSQIRAVIIIQSFYRMYLARKLFVKMKCAVLAIEKWRRKIITTRLKQAYKKENCVIICQAIVRRFIQRRKFLKIQRGVILIQNHYRRRKAKETLKILKIEARSINHIKFVNKGLENKIIELTQKLDTKEKEM---------CXXXXXXXXXXXXXXXXXXXXXAESAKIYQNTVQDLQTEIIQLKKELNREIVEKNKI--FADKELLEINYKKKINYLENLIEELKSSPSVI-----EPNIICNGDEAQQSICQDEHQKFI-----------NEQMDHQKLVREYEKLEMKYENLYKEFLFVKSSNQKPSINYDNQTSNDSETESTFSKDDADVESLSDKVDAKTTKEHXXXXXXXXXXLPNFISESISTAGDLAVVMQLQMNISSLSQENNRLKETVQQFEDELLKYEQCAEDSKGLVIHNEYDNELLSIIKDIKGMDEHGLKSRLIDEVANLKKKLKQSN-EDYQKLRLHIFDGSMSKLTGNLDHESINSEEEELKRA-FESQKEANRK------------MLKEIEGIKANNVDLKKALFQIRKDKEQLQVQLGKQHLMIRHGVEYL----QNLK---------------LTPKERLDKFVQNEISRILLENLKLQERNDQIISETIELKRGLKYFAFRLQKYEGSLVPNPNKEEDLLQLIQNVIYHSKMKTIGKRECYSEIGLIDLNMSELSIFIKSFIFDLSP-SICLQYEPYHLVPYIIFMVTRKFDFYKEEDQMTNFLSKLIVALKRTIRKRRNYIEYLVMLLSNVFCLVNLXXXXXXXXXXXXLNTAEDIQHYFVHYDLNEFIRLLKELCVTLFQMILKTIVDNLLPQSLCIDAILVHEAI--IDFLSKDGTKYKSNIETQPKNTSFNVLTKNLQSVLEILKNHKIPQLIINQIFVHIAYLINAYCLNTLLFRTDLCYFSKGLQIKYNLSSFETWIRYQKLIDSGALQCLRPMTEAVQLLQTLIDSDEDAKFVCDMCEYLNTRQVVKILNNFNPRDGYGCRLSSGLIAKIETQMKIKRGDEPSESKLETPTVIEIPIDIPFIHNGVSLCRTIIPKPLYLSCLT 5575
MA E+Y+K ++WIPD E VW A +L+ +K + V+++ + G E L K K P LRNPDIL+G+ DLT LSYL+EP VL+NL++RF + + IYTYCGIVLVAINPY++L IYG++IINAY QN D+DPHIFAVAE A+++M+ NQSIIVSGESGAGKTVSAKY MRYFA V GS +E +E KVL SNPI+E+ GNAKT RNDNSSRFGKY+EI F+ R ++IGANM TYLLEKSRVVFQ ERNYHIFYQ+ C S T + N + Y + G S IDG+DD+ E + T+ + LGI + I ILA ILHLGN+ F D+ +I + L + L+G +++ WLC R ++T ET KP+SK A RDA K +Y+NLF+WIV NK L + V + FI VLDIYGFETF NSFEQFCIN+ANEKLQ QFN+HVFKLEQEEYM E + WT ID+Y+NQPCI+LIE+++G+LDLLDEECK+ KGSD+ W K+Y+ HLNK A F KP+LSN FII+HFA VEY+C GF+EKN+D+V EEQI +LK+S +L+ ELF+D E I T+ + S T + + + +++ KKTVG QFRNSL LM+ LN T PHYVRCIKPND K PFTF +RAVQQLRACGVLETIR+SAAGFPSRWTY +F+ RY +LM +V + D K + ++E LI D ++FG TK+FFR GQVA LEK+R K+ ++ IQ +RG + RKKY+ + + + IQ Y+R A AT L + RA IIIQ F RMY+ RK + M+ A +A++ R + Q +E+ II Q VR ++ R + + + ++ +Q YRR AK LK LKIEARS+ K ++ GLENKI++L +K+D + KE I EK + E AK N V LQ EI +L+KEL++ EK I +ADK YK + E L+ ELK +++ E N + D+A++ I + +K + +E++ +Q L+ E+ +LE +Y++L K+ + + S KP + T + +E+E TFS + + E L +++ + K+ D+++ ++LQ ++ L QE L++ + + E++ L+ + E+ + + E + E L K + +L +E+ L+K L ++ + + + +LT + + EE + R+ SQKEA + +L++++ +K + ++ +A +++ L+ QL Q + +E L Q+LK L P+ R++ +Q+EI+R+ ENL L E+ ++ +LK+ LK FA ++ + E + N + + + + I+ V K K G+++ + +K+ I +L P + + P L YI+FM R D+ ++ ++ + L+ I +K+ ++KR + E + LSN ++ +QYSG + F NT +H ++DL E+ ++L +L + ++Q +++ +++N+L Q + + +L HE I + + G + +++ + + + + L S ++ H + +I Q+ + Y+I A LN LL R D+C +SKG+QI+YN+S E W+R + L++SGA + L P+ +A QLLQ +DEDA+ +C MC L T Q+VK+LN + P + + R+ I I+ +++ R D P +L P+ PF + ++L IP L L ++
Sbjct: 1 MAASELYTKYARVWIPDPEEVWKSAELLKDYKPGDKVLQLRLEEGKDLEYCLDPKTKELPPLRNPDILVGENDLTALSYLHEPAVLHNLKVRFIDSKLIYTYCGIVLVAINPYEQLPIYGEDIINAYSGQNMGDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYFATVSGSA-------SEANVEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRIIGANMRTYLLEKSRVVFQAEEERNYHIFYQL---CASAALPEFKTLRLGNANYFHYTKQGGSPVIDGIDDAKEMVNTRQACTLLGISDSYQMGIFRILAGILHLGNVEFASRDSDSCAIPPKHDPLTIFCDLMGVDYEEMAHWLCHRKLATATETYIKPISKLHAINARDALAKHIYANLFNWIVDHVNKALHSTVK-----------------QHSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKEQIPWTLIDFYDNQPCINLIEAKMGVLDLLDEECKMPKGSDDTWAQKLYNTHLNKCALFEKPRLSNKAFIIKHFADKVEYQCEGFLEKNKDTVYEEQIKVLKSSKKFKLLPELFQDEEKAISPTSATPSGRVPLSRTPVKPAKARPGQTSKEHKKTVGHQFRNSLHLLMETLNATTPHYVRCIKPNDFKFPFTFDEKRAVQQLRACGVLETIRISAAGFPSRWTYQEFFSRYRVLMKQKDVLS-DRKQTCKNVLEKLILDKDKYQFGKTKIFFRAGQVAYLEKIRADKLRAACIRIQKTIRGWLMRKKYMRMRRAAITIQRYVRGHQARCYATFLRRTRAAIIIQKFQRMYVVRKRYQCMRDATIALQALLRGYLVRNKYQMMLREHKSIIIQKHVRGWLARVHYHRTLKAIVYLQCCYRRMMAKRELKKLKIEARSVERYKKLHIGLENKIMQLQRKIDEQNKEYKSLLEKMNNLEITYSTETEKLRSDVERLRMSEEEAKNATNRVLSLQEEIAKLRKELHQTQTEKKTIEEWADK------YKHET---EQLVSELKEQNTLLKTEKEELNRRIH-DQAKE-ITETMEKKLVEETKQLELDLNDERLRYQNLLNEFSRLEERYDDL-KDEMNLMVSIPKPGHKRTDSTHSSNESEYTFSSEITEAEDLPLRMEEPSEKK---------------------APLDMSLFLKLQKRVTELEQEKQSLQDELDRKEEQALR-AKAKEEERPPIRGAELEYESL------KRQELESENKKLKNELNELQKALTETRAPEVTAPGAPAYRVLLDQLTSVSEELEVRKEEVLILRSQLVSQKEAIQPKEDKNTMTDSTILLEDVQKMK-DKGEIAQAYIGLKETNRLLESQLQSQKKSHENELESLRGEIQSLKEENNRQQQLLAQNLQLPPEARIEASLQHEITRLTNENLDLMEQLEKQDKTVRKLKKQLKVFAKKIGELEVGQMENISPGQIIDEPIRPVNIPRKEKDFQ--------GMLEYKKEDEQKLVKNLILELKPRGVAVNLIP-GLPAYILFMCVRHADYLNDDQKVRSLLTSTINGIKKVLKKRGDDFETVSFWLSNTCRFLHCLKQYSGEEGFMKHNTPRQNEHCLTNFDLAEYRQVLSDLAIQIYQQLVR-VLENIL-QPMIVSGMLEHETIQGVSGVKPTGLRKRTSSIADEGTYTLDSIIRQLNSFHSVMCQHGMDPELIKQVVKQMFYIIGAVTLNNLLLRKDMCSWSKGMQIRYNVSQLEEWLRDKNLMNSGAKETLEPLIQAAQLLQVKKKTDEDAEAICSMCNALTTAQIVKVLNLYTPVNEFEERVLVSFIRTIQLRLR-DRKDSP---QLLMDAKHIFPVTFPFNPSSLALETIQIPASLGLGFIS 1827
BLAST of Dach-2 vs. UniProt/SwissProt
Match: sp|Q9QYF3|MYO5A_RAT (Unconventional myosin-Va OS=Rattus norvegicus OX=10116 GN=Myo5a PE=1 SV=1) HSP 1 Score: 1104.35 bits (2855), Expect = 0.000e+0 Identity = 710/1901 (37.35%), Postives = 1080/1901 (56.81%), Query Frame = 2
Query: 47 MALYEMYSKGVKIWIPDEESVWIGATVLQFHKEKN-VIKIITDNGISKELNLSSKKCA-PFLRNPDILIGQKDLTYLSYLNEPEVLYNLQIRFCERREIYTYCGIVLVAINPYQELSIYGKEIINAYHSQNSVDLDPHIFAVAENAFRRMSSFGENQSIIVSGESGAGKTVSAKYTMRYFALVGGSKTKQSFNLTETQIERKVLLSNPILEAFGNAKTIRNDNSSRFGKYLEILFNPRNQVIGANMCTYLLEKSRVVFQNLGERNYHIFYQIVTHCQSEDELLMNTGLVNNVEMYDYLRYGESLEIDGVDDSHEFLITKNSFLQLGIDLNKFKTICEILAAILHLGNIRFRFHDATDSSIIENPELLKLIAGLLGCSIDQLKIWLCFRTISTFQETLHKPLSKAEAQYFRDAFVKTLYSNLFDWIVKQANKVLSTDVSINIKKKLKKTIVVNQEDKKKFIAVLDIYGFETFAENSFEQFCINFANEKLQLQFNLHVFKLEQEEYMNEGLEWTFIDYYNNQPCIDLIESRXXXXXXXXXXXXXXXXSDENWCCKIYSHHLNKSANFNKPKLSNMVFIIEHFAGPVEYKCAGFIEKNRDSVLEEQINLLKASDVQLIAELFRDSEIEIFDTNNXXXXXXXXXXXXXXXXXXQ--ENTRKMKKTVGSQFRNSLKSLMDALNKTNPHYVRCIKPNDLKLPFTFCPERAVQQLRACGVLETIRLSAAGFPSRWTYSDFYHRYYILMSNFNVKNHDFKAGSQKIVETLITVPDAFRFGNTKLFFRPGQVALLEKLRGHKIESSVTLIQSILRGSIERKKYLIIHKLTVQIQTYIRRKLAIEKATKLSQIRAVIIIQSFYRMYLARKLFVKMKCAVLAIEKWRRKIITTRLKQAYKKENCVIICQAIVRRFIQRRKFLKIQRGVILIQNHYRRRKAKETLKILKIEARSINHIKFVNKGLENKIIELTQKLDTKEKEM-CXXXXXX--------XXXXXXXXXXXXXXXAESAKIYQNTVQDLQTEIIQLKKELNREIVEKNKI--FADKELLEINYKKKINYL-ENLIEE---LKSSPSVIEPNIICNGDEAQQSICQD--EHQKFI-----NEQMDHQKLVREYEKLEMKYENLYKEFLFVKSSNQKPSINYDNQTSNDSETESTFSKDDADVESLSDKVDAKTTKEHXXXXXXXXXXLPNFISESISTAGDLAVVMQLQMNISSLSQENNRLKETVQQFEDELLKYEQCAEDSKGLVIHNEYDNELLSIIKDIKGMDEHGLKSRLIDEVANLKKKL-KQSNEDYQKLRLHIFDGSMSKLTGNLDHESINSEEEELKRA-FESQKEANRK------------MLKEIEGIKANNVDLKKALFQIRKDKEQLQVQLGKQHLMIRHGVEYL----QNLK---------------LTPKERLDKFVQNEISRILLENLKLQERNDQIISETIELKRGLKYFAFRLQKYEGSLVPNPNKEEDLLQLIQNVIYHSKMKTIGKRECYSEIGLIDLNMSELSIFIKSFIFDLSPSICLQYEPYHLVPYIIFMVTRKFDFYKEEDQMTNFLSKLIVALKRTIRKRRNYIEYLVMLLSNVFCLVNLXXXXXXXXXXXXLNTAEDIQHYFVHYDLNEFIRLLKELCVTLFQMILKTIVDNLLPQSLCIDAILVHEAI--IDFLSKDGTKYKSNIETQPKNTSFNVLTKNLQSVLEILKNHKIPQLIINQIFVHIAYLINAYCLNTLLFRTDLCYFSKGLQIKYNLSSFETWIRYQKLIDSGALQCLRPMTEAVQLLQTLIDSDEDAKFVCDMCEYLNTRQVVKILNNFNPRDGYGCRLSSGLIAKIETQMKIKRGDEPSESKLETPTVIEIPIDIPFIHNGVSLCRTIIPKPLYLS 5566
MA E+Y+K ++WIPD E VW A +L+ +K + V+ + + G E L K P LRNPDIL+G+ DLT LSYL+EP VL+NL++RF + + IYTYCGIVLVAINPY++L IYG++IINAY QN D+DPHIFAVAE A+++M+ NQSIIVSGESGAGKTVSAKY MRYFA V GS +E +E KVL SNPI+E+ GNAKT RNDNSSRFGKY+EI F+ R ++IGANM TYLLEKSRVVFQ ERNYHIFYQ+ + + ++ G N + + Y + G S I+GVDD+ E T+ + LGI + I ILA ILHLGN+ F D+ +I E L + L+G +++ WLC R ++T ET KP+SK +A RDA K +Y+ LF+WIV N+ L + V + FI VLDIYGFETF NSFEQFCIN+ANEKLQ QFN+HVFKLEQEEYM E + WT ID+Y+NQPCI+LIES+LG+LDLLDEECK+ KG+D+ W K+Y+ HLNK A F KP++SN FII+HFA VEY+C GF+EKN+D+V EEQI +LK+S +++ ELF+D E I T+ + + + + + + ++ KKTVG QFRNSL LM+ LN T PHYVRCIKPND K PFTF +RAVQQLRACGVLETIR+SAAGFPSRWTY +F+ RY +LM +V D K Q ++E LI D ++FG TK+FFR GQVA LEKLR K+ ++ IQ +RG + RK+YL + + + +Q Y+R A A L + +A IQ ++RMY+ R+ + + A + ++ + R + + +E+ +I Q VR ++ R + + + +I +Q +RR AK LK LKIEARS+ K ++ G+ENKI++L +K+D + K+ CL++ EK + E AK+ V LQ EI +L+K+L + EK I ADK YK++ L NL EE LK + ++ E +++ + E K + +E++ +Q L+ E+ +LE +Y++L KE + + + KP + T + +E+E TFS + A+ E ++ + + T K+ D+++ ++LQ ++ L QE +++ + + E+++L+ + +KG EL + +K + +L +E+ L+K L ++S + + M +LT + + EE + R+ SQKEA + +L++++ +K + ++ +A +++ L+ QL Q + E L Q+LK L P+ R++ +Q+EI+R+ ENL L E+ ++ +LK+ LK FA ++ + E + N + + + + I+ V K K G+++ + +K+ I +L P L YI+FM R D+ ++ ++ + L+ I ++K+ ++KR + E + LSN ++ +QYSG + F NT+ +H ++DL E+ ++L +L + ++Q +++ +++N+L Q + + +L HE I + + G + +++ + + + + L S ++ H + +I Q+ + Y++ A LN LL R D+C +SKG+QI+YN+S E W+R + L++SGA + L P+ +A QLLQ +D+DA+ +C MC L T Q+VK+LN + P + + R+S I I+ +++ R D P +L P+ PF + ++L IP L L
Sbjct: 1 MAASELYTKFARVWIPDPEEVWKSAELLKDYKPGDKVLLLHLEEGKDLEYRLDPKTSELPHLRNPDILVGENDLTALSYLHEPAVLHNLRVRFIDSKLIYTYCGIVLVAINPYEQLPIYGEDIINAYSGQNMGDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYFATVSGSA-------SEANVEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRIIGANMRTYLLEKSRVVFQAEEERNYHIFYQLCASAKLPEFKMLRLG---NADSFHYTKQGGSPMIEGVDDAKEMAHTRQACTLLGISESYQMGIFRILAGILHLGNVGFASRDSDSCTIPPKHEPLIIFCDLMGVDYEEMCHWLCHRKLATATETYIKPISKLQATNARDALAKHIYAKLFNWIVGHVNQALHSAVK-----------------QHSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKEQIPWTLIDFYDNQPCINLIESKLGILDLLDEECKMPKGTDDTWAQKLYNTHLNKCALFEKPRMSNKAFIIKHFADKVEYQCEGFLEKNKDTVFEEQIKVLKSSKFKMLPELFQDDEKAISPTSATSSGRTPLTRVPVKPTKGRPGQTAKEHKKTVGLQFRNSLHLLMETLNATTPHYVRCIKPNDFKFPFTFDEKRAVQQLRACGVLETIRISAAGFPSRWTYQEFFSRYRVLMKQKDVLG-DRKQTCQNVLEKLILDKDKYQFGKTKIFFRAGQVAYLEKLRADKLRAACIRIQKTIRGWLLRKRYLCMQRAAITVQRYVRGYQARCYAKFLRRTKAATTIQKYWRMYVVRRKYKIRRAATIVLQSYLRGYLARNRYRKILREHKAVIIQKRVRGWLARTHYKRTMKAIIYLQCCFRRMMAKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLMEKLTNLEGVYNSETEKLRNDVERLQLSEEEAKVATGRVLSLQEEIAKLRKDLEQTRSEKKSIEERADK------YKQETEQLVSNLKEENTLLKQEKETLNHLMVEQAKEMTETMERKLVEETKQLELDLNDERLRYQNLLNEFSRLEERYDDL-KEEMTLMLNVPKPGHKRTDSTHSSNESEYTFSSEFAETEDIAPRTEEPTEKK---------------------VPLDMSLFLKLQKRVTELGQEKQLMQDELDRKEEQVLRSK-----AKGGERPQIRGAEL--GYESLKRQELESENKKLKNELNELRKALSEKSAPEVNAPGAPAYRVLMEQLTAVSEELDVRKEEVLILRSQLVSQKEAIQPKDDKNTMTDSTILLEDVQKMK-DKGEIAQAYIGLKETNRLLESQLQSQKRSHENEAEALRGEIQSLKEENNRQQQLLAQNLQLPPEARIEASLQHEITRLTNENLDLMEQLEKQDKTVRKLKKQLKVFAKKIGELEVGQMENISPGQIIDEPIRPVNIPRKGKDFQ--------GMLEYKREDEQKLVKNLILELKPRGVAVNLISGLPAYILFMCVRHADYLDDDQKVRSLLTSTINSIKKVLKKRGDDFETVSFWLSNTCRFLHCLKQYSGEEGFMKHNTSRQNEHCLTNFDLAEYRQVLSDLAIQIYQQLVR-VLENIL-QPMIVSGMLEHETIQGVSGVKPTGLRKRTSSIADEGTYTLDSILRQLNSFHSVMCQHGMDPELIKQVVKQMFYIVGAITLNNLLLRKDMCSWSKGMQIRYNVSQLEEWLRDKNLMNSGAKETLEPLIQAAQLLQVKKKTDDDAEAICSMCNALTTAQIVKVLNLYTPVNEFEERVSVSFIRTIQVRLR-DRKDSP---QLLMDAKHIFPVTFPFNPSSLALETIQIPASLGLG 1823
BLAST of Dach-2 vs. UniProt/SwissProt
Match: sp|Q99104|MYO5A_MOUSE (Unconventional myosin-Va OS=Mus musculus OX=10090 GN=Myo5a PE=1 SV=2) HSP 1 Score: 1095.49 bits (2832), Expect = 0.000e+0 Identity = 710/1930 (36.79%), Postives = 1084/1930 (56.17%), Query Frame = 2
Query: 47 MALYEMYSKGVKIWIPDEESVWIGATVLQFHKEKN-VIKIITDNGISKELNLSSKKCA-PFLRNPDILIGQKDLTYLSYLNEPEVLYNLQIRFCERREIYTYCGIVLVAINPYQELSIYGKEIINAYHSQNSVDLDPHIFAVAENAFRRMSSFGENQSIIVSGESGAGKTVSAKYTMRYFALVGGSKTKQSFNLTETQIERKVLLSNPILEAFGNAKTIRNDNSSRFGKYLEILFNPRNQVIGANMCTYLLEKSRVVFQNLGERNYHIFYQIVTHCQSEDELLMNTGLVNNVEMYDYLRYGESLEIDGVDDSHEFLITKNSFLQLGIDLNKFKTICEILAAILHLGNIRFRFHDATDSSIIENPELLKLIAGLLGCSIDQLKIWLCFRTISTFQETLHKPLSKAEAQYFRDAFVKTLYSNLFDWIVKQANKVLSTDVSINIKKKLKKTIVVNQEDKKKFIAVLDIYGFETFAENSFEQFCINFANEKLQLQFNLHVFKLEQEEYMNEGLEWTFIDYYNNQPCIDLIESRXXXXXXXXXXXXXXXXSDENWCCKIYSHHLNKSANFNKPKLSNMVFIIEHFAGPVEYKCAGFIEKNRDSVLEEQINLLKASDVQLIAELFRDSEIEIFDTNNXXXXXXXXXXXXXXXXXXQ--ENTRKMKKTVGSQFRNSLKSLMDALNKTNPHYVRCIKPNDLKLPFTFCPERAVQQLRACGVLETIRLSAAGFPSRWTYSDFYHRYYILMSNFNVKNHDFKAGSQKIVETLITVPDAFRFGNTKLFFRPGQVALLEKLRGHKIESSVTLIQSILRGSIERKKYLIIHKLTVQIQTYIRRKLAIEKATKLSQIRAVIIIQSFYRMYLARKLFVKMKCAVLAIEKWRRKIITTRLKQAYKKENCVIICQAIVRRFIQRRKFLKIQRGVILIQNHYRRRKAKETLKILKIEARSINHIKFVNKGLENKIIELTQKLDTKEKEM-CXXXXXX--------XXXXXXXXXXXXXXXAESAKIYQNTVQDLQTEIIQLKKELNREIVEKNKI--FADKELLEINYKKKINYL-ENLIEE---LKSSPSVIEPNIICNGDEAQQSICQD--EHQKFI-----NEQMDHQKLVREYEKLEMKYENLYKEFLFVKSSNQKPSINYDNQTSNDSETESTFSKDDADVESLSDKVDAKTTKEHXXXXXXXXXXLPNFISESISTAGDLAVVMQLQMNISSLSQENNRLKETVQQFEDELLKYEQCAEDSKGLVIHNEYDNELLSIIKDIKGMDEHGLKSRLIDEVANLKKKL-KQSNEDYQKLRLHIFDGSMSKLTGNLDHESINSEEEELKRA-FESQKEANRK------------MLKEIEGIKANNVDLKKALFQIRKDKEQLQVQLGKQHLMIRHGVEYL----QNLK---------------LTPKERLDKFVQNEISRILLENLKLQ----------------------------ERNDQIISETIELKRGLKYFAFRLQKYEGSLVPNPNKEEDLLQLIQNVIYHSKMKTIGKRECYSEIGLIDLNMSELSIFIKSFIFDLSP-SICLQYEPYHLVPYIIFMVTRKFDFYKEEDQMTNFLSKLIVALKRTIRKRRNYIEYLVMLLSNVFCLVNLXXXXXXXXXXXXLNTAEDIQHYFVHYDLNEFIRLLKELCVTLFQMILKTIVDNLLPQSLCIDAILVHEAI--IDFLSKDGTKYKSNIETQPKNTSFNVLTKNLQSVLEILKNHKIPQLIINQIFVHIAYLINAYCLNTLLFRTDLCYFSKGLQIKYNLSSFETWIRYQKLIDSGALQCLRPMTEAVQLLQTLIDSDEDAKFVCDMCEYLNTRQVVKILNNFNPRDGYGCRLSSGLIAKIETQMKIKRGDEPSESKLETPTVIEIPIDIPFIHNGVSLCRTIIPKPLYLS 5566
MA E+Y+K ++WIPD E VW A +L+ +K + V+ + + G E L K P LRNPDIL+G+ DLT LSYL+EP VL+NL++RF + + IYTYCGIVLVAINPY++L IYG++IINAY QN D+DPHIFAVAE A+++M+ NQSIIVSGESGAGKTVSAKY MRYFA V GS +E +E KVL SNPI+E+ GNAKT RNDNSSRFGKY+EI F+ R ++IGANM TYLLEKSRVVFQ ERNYHIFYQ+ + + ++ G N + + Y + G S I+GVDD+ E T+ + LGI + I ILA ILHLGN+ F D+ +I E L + L+G +++ WLC R ++T ET KP+SK +A RDA K +Y+ LF+WIV N+ L + V + FI VLDIYGFETF NSFEQFCIN+ANEKLQ QFN+HVFKLEQEEYM E + WT ID+Y+NQPCI+LIES+LG+LDLLDEECK+ KG+D+ W K+Y+ HLNK A F KP++SN FII+HFA VEY+C GF+EKN+D+V EEQI +LK+S +++ ELF+D E I T+ + + + + + + ++ KKTVG QFRNSL LM+ LN T PHYVRCIKPND K PFTF +RAVQQLRACGVLETIR+SAAGFPSRWTY +F+ RY +LM +V D K + ++E LI D ++FG TK+FFR GQVA LEKLR K+ ++ IQ +RG + RK+YL + + + +Q Y+R A A L + +A IQ ++RMY+ R+ + + A + I+ + R +T + +E +I Q VR ++ R + + + ++ +Q +RR AK LK LKIEARS+ K ++ G+ENKI++L +K+D + K+ CL++ EK + E AK+ V LQ EI +L+K+L + EK I ADK YK++ + L NL EE LK + I+ E +++ + E K + +E++ +Q L+ E+ +LE +Y++L KE + + + KP + T + +E+E TFS + A+ E ++ + + K+ D+++ ++LQ ++ L QE +++ + + E+++ + + E+ + + E + E L K + +L +E+ L+K L ++S + + M +LT + + EE + R+ SQKEA + +L++++ +K + ++ +A +++ L+ QL Q + E L Q+LK L P+ R++ +Q+EI+R+ ENL + E+ D+ + +LK+ LK FA ++ + E + N + + + + I+ V K K G+++ + +K+ I +L P + + P L YI+FM R D+ ++ ++ + L+ I ++K+ ++KR + E + LSN ++ +QYSG + F NT+ +H ++DL E+ ++L +L + ++Q +++ +++N+L Q + + +L HE I + + G + +++ + + + + L S ++ H + +I Q+ + Y++ A LN LL R D+C +SKG+QI+YN+S E W+R + L++SGA + L P+ +A QLLQ +D+DA+ +C MC L T Q+VK+LN + P + + R+S I I+ +++ R D P +L P+ PF + ++L IP L L
Sbjct: 1 MAASELYTKFARVWIPDPEEVWKSAELLKDYKPGDKVLLLHLEEGKDLEYRLDPKTGELPHLRNPDILVGENDLTALSYLHEPAVLHNLRVRFIDSKLIYTYCGIVLVAINPYEQLPIYGEDIINAYSGQNMGDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYFATVSGSA-------SEANVEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRIIGANMRTYLLEKSRVVFQAEEERNYHIFYQLCASAKLPEFKMLRLG---NADSFHYTKQGGSPMIEGVDDAKEMAHTRQACTLLGISESYQMGIFRILAGILHLGNVGFASRDSDSCTIPPKHEPLTIFCDLMGVDYEEMCHWLCHRKLATATETYIKPISKLQATNARDALAKHIYAKLFNWIVDHVNQALHSAVK-----------------QHSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKEQIPWTLIDFYDNQPCINLIESKLGILDLLDEECKMPKGTDDTWAQKLYNTHLNKCALFEKPRMSNKAFIIKHFADKVEYQCEGFLEKNKDTVFEEQIKVLKSSKFKMLPELFQDDEKAISPTSATSSGRTPLTRVPVKPTKGRPGQTAKEHKKTVGHQFRNSLHLLMETLNATTPHYVRCIKPNDFKFPFTFDEKRAVQQLRACGVLETIRISAAGFPSRWTYQEFFSRYRVLMKQKDVLG-DRKQTCKNVLEKLILDKDKYQFGKTKIFFRAGQVAYLEKLRADKLRAACIRIQKTIRGWLLRKRYLCMQRAAITVQRYVRGYQARCYAKFLRRTKAATTIQKYWRMYVVRRRYKIRRAATIVIQSYLRGYLTRNRYRKILREYKAVIIQKRVRGWLARTHYKRTMKAIVYLQCCFRRMMAKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLMEKLTNLEGVYNSETEKLRNDVERLQLSEEEAKVATGRVLSLQEEIAKLRKDLEQTRSEKKSIEERADK------YKQETDQLVSNLKEENTLLKQEKETLNHRIVEQAKEMTETMERKLVEETKQLELDLNDERLRYQNLLNEFSRLEERYDDL-KEEMTLMLNVPKPGHKRTDSTHSSNESEYTFSSEFAETEDIAPRTEEPIEKK---------------------VPLDMSLFLKLQKRVTELEQEKQLMQDELDRKEEQVFR-SKAKEEERPQIRGAELEYESL------KRQELESENKKLKNELNELRKALSEKSAPEVTAPGAPAYRVLMEQLTSVSEELDVRKEEVLILRSQLVSQKEAIQPKDDKNTMTDSTILLEDVQKMK-DKGEIAQAYIGLKETNRLLESQLQSQKRSHENEAEALRGEIQSLKEENNRQQQLLAQNLQLPPEARIEASLQHEITRLTNENLYFEELYADDPKKYQSYRISLYKRMIDLMEQLEKQDKTVR---KLKKQLKVFAKKIGELEVGQMENISPGQIIDEPIRPVNIPRKEKDFQ--------GMLEYKREDEQKLVKNLILELKPRGVAVNLIP-GLPAYILFMCVRHADYLNDDQKVRSLLTSTINSIKKVLKKRGDDFETVSFWLSNTCRFLHCLKQYSGEEGFMKHNTSRQNEHCLTNFDLAEYRQVLSDLAIQIYQQLVR-VLENIL-QPMIVSGMLEHETIQGVSGVKPTGLRKRTSSIADEGTYTLDSILRQLNSFHSVMCQHGMDPELIKQVVKQMFYIVGAITLNNLLLRKDMCSWSKGMQIRYNVSQLEEWLRDKNLMNSGAKETLEPLIQAAQLLQVKKKTDDDAEAICSMCNALTTAQIVKVLNLYTPVNEFEERVSVSFIRTIQMRLR-DRKDSP---QLLMDAKHIFPVTFPFNPSSLALETIQIPASLGLG 1848
BLAST of Dach-2 vs. UniProt/SwissProt
Match: sp|P21271|MYO5B_MOUSE (Unconventional myosin-Vb OS=Mus musculus OX=10090 GN=Myo5b PE=1 SV=2) HSP 1 Score: 1094.34 bits (2829), Expect = 0.000e+0 Identity = 713/1902 (37.49%), Postives = 1080/1902 (56.78%), Query Frame = 2
Query: 47 MALYEMYSKGVKIWIPDEESVWIGATVLQFHKEKN---VIKIITDNGISKELNLSSKKCAPFLRNPDILIGQKDLTYLSYLNEPEVLYNLQIRFCERREIYTYCGIVLVAINPYQELSIYGKEIINAYHSQNSVDLDPHIFAVAENAFRRMSSFGENQSIIVSGESGAGKTVSAKYTMRYFALVGGSKTKQSFNLTETQIERKVLLSNPILEAFGNAKTIRNDNSSRFGKYLEILFNPRNQVIGANMCTYLLEKSRVVFQNLGERNYHIFYQIVTHCQSEDELLMNTGLVNNVEMYDYLRYGESLEIDGVDDSHEFLITKNSFLQLGIDLNKFKTICEILAAILHLGNIRFRFHDATDS-SIIENPELLKLIAGLLGCSIDQLKIWLCFRTISTFQETLHKPLSKAEAQYFRDAFVKTLYSNLFDWIVKQANKVLSTDVSINIKKKLKKTIVVNQEDKKKFIAVLDIYGFETFAENSFEQFCINFANEKLQLQFNLHVFKLEQEEYMNEGLEWTFIDYYNNQPCIDLIESRXXXXXXXXXXXXXXXXSDENWCCKIYSHHLNKSANFNKPKLSNMVFIIEHFAGPVEYKCAGFIEKNRDSVLEEQINLLKASDVQLIAELFRDSEIEIFDTNNXXXXXXXXXXXXXXXXXXQENTRKMKKTVGSQFRNSLKSLMDALNKTNPHYVRCIKPNDLKLPFTFCPERAVQQLRACGVLETIRLSAAGFPSRWTYSDFYHRYYILMSNFNVKNHDFKAGSQKIVETLITVPDAFRFGNTKLFFRPGQVALLEKLRGHKIESSVTLIQSILRGSIERKKYLIIHKLTVQIQTYIRRKLAIEKATKLSQIRAVIIIQSFYRMYLARKLFVKMKCAVLAIEKWRRKIITTRLKQAYKKENCVIICQAIVRRFIQRRKFLKIQRGVILIQNHYRRRKAKETLKILKIEARSINHIKFVNKGLENKIIELTQKLDTKEKEMCXXXXXXXXXXXXXXXXXXXXXAESAKIYQNTVQD----LQTEIIQLKKELNREIVEKNKIFAD---KELLEINYKKKINYLENLIEELKSSPSVIEPNIICNGD-EAQQSICQDE---HQKFINEQMDHQKLVREYEKLEMKYENLYKEFLFVKSSNQKPSINYDNQTSNDSETESTFSKDDADVESLSDKVDAKTTKEHXXXXXXXXXXLPNFISESISTAGDLAVVMQLQMNISSLSQENNRLKETVQQFEDELLKYEQCAEDSKGLVIHNEYD----------------------NELLSIIKDIKGMDEHGLKSRLIDEVANLKKKLKQSNEDYQK-------LRLHIFDGSMSKLTGNLDHESINS-----------EEEELKRAFESQKEANRKMLKEIEGIKANNVDLKKALFQIRKDKEQLQVQLGKQHLMIRHGVEYLQNLKLTPKERLDKFVQNEISRILLENLKLQERNDQIISETIELKRGLKYFAFRLQKYEG--SLVPNPNKEEDLLQLIQNVIYHSKMKTIGKRECYSEIGLIDLNMSELSIFIKSFIFDLSPSICLQYEPYHLVPYIIFMVTRKFDFYKEEDQMTNFLSKLIVALKRTIRKRRNYIEYLVMLLSNVFCLVNLXXXXXXXXXXXXLNTAEDIQHYFVHYDLNEFIRLLKELCVTLFQMILKTIVDNLLPQSLCIDAILVHEAI--IDFLSKDGTKYKSNIETQPKNT-SFNVLTKNLQSVLEILKNHKIPQLIINQIFVHIAYLINAYCLNTLLFRTDLCYFSKGLQIKYNLSSFETWIRYQKLIDSGALQCLRPMTEAVQLLQTLIDSDEDAKFVCDMCEYLNTRQVVKILNNFNPRDGYGCRLSSGLIAKIETQMKIKRGDEPSESKLETPTVIEIPIDIPFIHNGVSLCRTIIPKPLYLSCL 5572
M+ E+Y++ ++WIPD + VW A + + +KE + +++ D + +++ + + PFLRNPDIL+G+ DLT LS+L+EP VL+NL++RF E IYTYCGIVLVAINPY++L IYG+++I AY QN D+DPHIFAVAE A+++M+ +NQSIIVSGESGAGKTVSAKY MRYFA VGGS + +T IE KVL S+PI+EA GNAKT RNDNSSRFGK++EI F+ + +IGANM TYLLEKSRVVFQ ERNYHIFYQ+ C + + E + Y +G + I+GV+D+ +F T+ + LG+ + +I +I+A+ILHLG++ + DS SI E L LLG Q++ WLC R + T ET K +S + RDA K +Y+ LF WIV+ NK L T + FI VLDIYGFETF NSFEQFCIN+ANEKLQ QFN HVFKLEQEEYM E + WT ID+Y+NQPCIDLIE++LG+LDLLDEECK+ KG+D+NW K+Y H N S +F KP++SN FI+ HFA VEY GF+EKNRD+V EEQIN+LKAS L+A+LF D + TN +K + S K + +S + + ++ KK+VG QFR SL LM+ LN T PHYVRCIKPND KLPF F P+RAVQQLRACGVLETIR+SAAG+PSRWTY DF++RY +LM + N D K + ++E+LI PD F+FG TK+FFR GQVA LEKLR K + +IQ +RG ++R KY + T+ +Q + R LA A L + RA I+ Q YRM AR+ + ++ A + I+ + R + R + E+ I Q R ++ R++FL+ + I+IQ +RR KA++ LK LKIEARS H+K +N G+ENK+++L +K+D + KE + QL + ++ + E A QN D LQ E+ L+ EL + E+ ++ D KE E+ +K++ LE+ LK + I+C E+ QS ++ ++ E+ +Q LV+EY +LE +YENL E Q P + SN S ES + + D DA E + A D+ V ++LQ + L QE +L+ +++ + + K Q + + GL + + D NEL + D + M ++ S D + L +LK +NE+ + LR I + +L+G +IN+ ++E+ A+ + NR + +++ A +++ ++ + ++ E L+ ++ KQ + Q L L+P+ +++ VQ EISR+ ENL +E +++ +LK+ LK + ++Q E +L + + +L + + T+ ++E + G+++ + + ++ I++ + DL P + P L YI++M R D+ ++ ++ + LS I +K+ ++K + E LSN ++ +QYSG + F NTA+ +H ++DL E+ ++L +L + ++Q ++K I + LL Q + + A+L +E+I + + G + +S+ +N+ + + + S +L + + II Q+F + Y+INA LN LL R D C +S G+Q++YN+S E W+R + L SGA+Q + P+ +A QLLQ + EDA+ +C +C L+T+Q+VKILN + P + + R++ I I+ Q++ +R D P + L++ V P+ P+ + +++ IP L L L
Sbjct: 1 MSYSELYTRYTRVWIPDPDEVWRSAELTKDYKEGDKSLQLRLEDDTILEYPVDVQNNQ-VPFLRNPDILVGENDLTALSHLHEPAVLHNLKVRFLESNHIYTYCGIVLVAINPYEQLPIYGQDVIYAYSGQNMGDMDPHIFAVAEEAYKQMARDEKNQSIIVSGESGAGKTVSAKYAMRYFATVGGSAS-------DTNIEEKVLASSPIMEAIGNAKTTRNDNSSRFGKFIEIGFDKKYHIIGANMRTYLLEKSRVVFQADDERNYHIFYQL---CAAASLPEFKELALTCAEDFFYTAHGGNTTIEGVNDADDFEKTRQALTLLGVRDSHQISIFKIIASILHLGSVEIQSERDGDSCSISPQDEHLSNFCSLLGIEHSQMEHWLCHRKLVTTSETYVKTMSLQQVVNARDALAKHIYAQLFSWIVEHINKALHTS-----------------HKQHSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNSHVFKLEQEEYMKEQIPWTLIDFYDNQPCIDLIEAKLGILDLLDEECKVPKGTDQNWAQKLYERHSN-SQHFQKPRMSNTAFIVNHFADKVEYLSDGFLEKNRDTVYEEQINILKASKFPLVADLFHDDKDSAPATNTAKNRSSSKINVRSSRPLIKVPNKEHKKSVGYQFRTSLNLLMETLNATTPHYVRCIKPNDEKLPFHFDPKRAVQQLRACGVLETIRISAAGYPSRWTYHDFFNRYRVLMKKRELTNTDKKNICKSVLESLIKDPDKFQFGRTKIFFRAGQVAYLEKLRADKFREATIMIQKSVRGWLQRVKYRRLRAATLSLQRFCRGYLARRLAEHLRRTRAAIVFQKQYRMLKARRAYRRVCRATVIIQSFTRAMFVRRNYRQVLMEHKATIIQKYARGWMARKRFLRERDAAIVIQCAFRRLKARQELKALKIEARSAEHLKRLNVGMENKVVQLQRKIDDQNKEFKTLSEQLSAVTSSHAVEVEKLKKELAHYQQNQEADTSLQLQEEVQSLRTELQKAHSER-RVLEDAHNKENGEL--RKRVADLEHENALLKDEKEYLNNQILCQSKAESSQSSVEENLLMKKELEEERSRYQNLVKEYSQLEQRYENLRDE--------QTPG--HRKNPSNQSSLESDSNYPSISTSEIGDTEDALQQVEEIGIE---------------KAAMDMTVFLKLQKRVRELEQERKKLQAQLEKGQQD-SKKGQVEQQNNGLDVDQDADIAYNSLKRQELESENKKLKNDLNELRKAVAD-QAMQDNSTHSS-PDSYSLLLNQLKLANEELEVRKEEVLILRTQIMNADQRRLSGKNMEPNINARTSWPNSEKHVDQEDAIEAYHGVCQTNRLLEAQLQ---AQSLEHEEEVEHLKAQVEALKEEMDKQQQT------FCQTLLLSPEAQVEFGVQQEISRLTNENLDFKELVEKLEKNERKLKKQLKIYMKKVQDLEAAQALAQSDRRHHELTRQV----------TVQRKEKDFQ-GMLEYHKEDEALLIRNLVTDLKPQMLSGTVPC-LPAYILYMCIRHADYTNDDLKVHSLLSSTINGIKKVLKKHNDDFEMTSFWLSNTCRFLHCLKQYSGDEGFMTQNTAKQNEHCLKNFDLTEYRQVLSDLSIQIYQQLIK-IAEGLL-QPMIVSAMLENESIQGLSGVRPTGYRKRSSSMVDGENSYCLEAIVRQMNSFHTVLCDQGLDPEIILQVFKQLFYMINAVTLNNLLLRKDACSWSTGMQLRYNISQLEEWLRGKNLHQSGAVQTMEPLIQAAQLLQLKKKTHEDAEAICSLCTSLSTQQIVKILNLYTPLNEFEERVTVSFIRTIQAQLQ-ERND-PQQLLLDSKHV--FPVLFPYNPSALTMDSIHIPACLNLEFL 1815
BLAST of Dach-2 vs. UniProt/SwissProt
Match: sp|Q9ULV0|MYO5B_HUMAN (Unconventional myosin-Vb OS=Homo sapiens OX=9606 GN=MYO5B PE=1 SV=3) HSP 1 Score: 1091.26 bits (2821), Expect = 0.000e+0 Identity = 716/1915 (37.39%), Postives = 1064/1915 (55.56%), Query Frame = 2
Query: 47 MALYEMYSKGVKIWIPDEESVWIGATVLQFHKE--KNVIKIITDNGISKELNLSSKKCAPFLRNPDILIGQKDLTYLSYLNEPEVLYNLQIRFCERREIYTYCGIVLVAINPYQELSIYGKEIINAYHSQNSVDLDPHIFAVAENAFRRMSSFGENQSIIVSGESGAGKTVSAKYTMRYFALVGGSKTKQSFNLTETQIERKVLLSNPILEAFGNAKTIRNDNSSRFGKYLEILFNPRNQVIGANMCTYLLEKSRVVFQNLGERNYHIFYQIVTHCQSEDELLMNTGLVNNVEMYDYLRYGESLEIDGVDDSHEFLITKNSFLQLGIDLNKFKTICEILAAILHLGNIRFRFHDATDSSIIENPEL-LKLIAGLLGCSIDQLKIWLCFRTISTFQETLHKPLSKAEAQYFRDAFVKTLYSNLFDWIVKQANKVLSTDVSINIKKKLKKTIVVNQEDKKKFIAVLDIYGFETFAENSFEQFCINFANEKLQLQFNLHVFKLEQEEYMNEGLEWTFIDYYNNQPCIDLIESRXXXXXXXXXXXXXXXXSDENWCCKIYSHHLNKSANFNKPKLSNMVFIIEHFAGPVEYKCAGFIEKNRDSVLEEQINLLKASDVQLIAELFRDSEIEIFDTNNXXXXXXXXXXXXXXXXXXQENTRKMKKTVGSQFRNSLKSLMDALNKTNPHYVRCIKPNDLKLPFTFCPERAVQQLRACGVLETIRLSAAGFPSRWTYSDFYHRYYILMSNFNVKNHDFKAGSQKIVETLITVPDAFRFGNTKLFFRPGQVALLEKLRGHKIESSVTLIQSILRGSIERKKYLIIHKLTVQIQTYIRRKLAIEKATKLSQIRAVIIIQSFYRMYLARKLFVKMKCAVLAIEKWRRKIITTRLKQAYKKENCVIICQAIVRRFIQRRKFLKIQRGVILIQNHYRRRKAKETLKILKIEARSINHIKFVNKGLENKIIELTQKLDTKEKEMCXXXXXXXXXXXXXXXXXXXXXAESAKIYQNTVQD----LQTEIIQLKKELNREIVEKNKIFADKELLEIN-YKKKINYLENLIEELKSSPSVIEPNIICNGDE--AQQSICQDEHQKFINEQMD-HQKLVREYEKLEMKYENLYKEFLFVKSSNQKPSINYDNQTSNDSETESTFSKDDADVESLSDKVDAKTTKEHXXXXXXXXXXLPNFISESISTAGDLAVVMQLQMNISSLSQENNRLKETVQQFEDELLKYEQCAEDSKGLVIHNEYD----------------------NELLSIIKD--IKGMDEHGLK---SRLIDEVANLKKKLKQSNEDYQKLRLHIFDGSMSKLTGNLDHESINS-----------EEEELKRAFESQKEANRKMLKEIEGIKANNVDLKKALFQIRKDKEQLQVQLGKQHL-------------------MIRHGVEYLQNLKLTPKERLDKFVQNEISRILLENLKLQERNDQIISETIELKRGLKYFAFRLQKYEG--SLVPNPNKEEDLLQLIQNVIYHSKMKTIGKRECYSEIGLIDLNMSELSIFIKSFIFDLSPSICLQYEPYHLVPYIIFMVTRKFDFYKEEDQMTNFLSKLIVALKRTIRKRRNYIEYLVMLLSNVFCLVNLXXXXXXXXXXXXLNTAEDIQHYFVHYDLNEFIRLLKELCVTLFQMILKTIVDNLLPQSLCIDAILVHEAIIDFLSKDGTKYK---SNIETQPKNTSFNVLTKNLQSVLEILKNHKIPQLIINQIFVHIAYLINAYCLNTLLFRTDLCYFSKGLQIKYNLSSFETWIRYQKLIDSGALQCLRPMTEAVQLLQTLIDSDEDAKFVCDMCEYLNTRQVVKILNNFNPRDGYGCRLSSGLIAKIETQMKIKRGDEPSESKLETPTVIEIPIDIPFIHNGVSLCRTIIPKPLYLSCL 5572
M++ E+YS+ ++WIPD + VW A + + +KE K++ + D I + + PFLRNPDIL+G+ DLT LSYL+EP VL+NL++RF E IYTYCGIVLVAINPY++L IYG+++I Y QN D+DPHIFAVAE A+++M+ +NQSIIVSGESGAGKTVSAKY MRYFA VGGS + ET IE KVL S+PI+EA GNAKT RNDNSSRFGKY++I F+ R +IGANM TYLLEKSRVVFQ ERNYHIFYQ+ C + + + E + Y G I+GVDD+ +F T+ +F LG+ + +I +I+A+ILHLG++ + DS I ++ L LLG Q++ WLC R + T ET K +S + R+A K +Y+ LF WIV+ NK L T + + FI VLDIYGFETF NSFEQFCIN+ANEKLQ QFN HVFKLEQEEYM E + WT ID+Y+NQPCIDLIE++LG+LDLLDEECK+ KG+D+NW K+Y H + S +F KP++SN FII HFA VEY GF+EKNRD+V EEQIN+LKAS L+A+LF D + + T K S S + +K N ++ KKTVG QFR SL LM+ LN T PHYVRCIKPND KLPF F P+RAVQQLRACGVLETIR+SAAG+PSRW Y DF++RY +L+ + N D KA + ++E LI PD F+FG TK+FFR GQVA LEKLR K ++ +IQ +RG +++ KY + T+ +Q Y R LA A L +IRA +++Q YRM AR+ + +++ A + I+ + R + R + E+ Q VR ++ RR F +++ I+IQ +R KA+ LK L+IEARS H+K +N G+ENK+++L +K+D + KE + QL + ++ + E Q+ +D LQ E+ L+ EL R E+ KI D E + +K++ LE LK + I+C + AQ S+ ++ +K + E+ +Q LV+EY +LE +Y+NL E +K Q P + SN S ES + + D DA E + A D+ V ++LQ + L QE +L+ +++ E + K Q + + D NEL + D + HG S L++++ ++L+ E+ LR I +L G +IN+ ++E+ A+ + N K E G + +L A +++ L+ QL Q L M + + Q L L+P+ +++ VQ EISR+ ENL L+E +++ +LK+ LK + + Q E +L + K +L ++ T+ ++E + G+++ + + ++ I++ + DL P + P L YI++M R D+ ++ ++ + L+ I +K+ ++K + E LSN L++ +QYSG + F NTA+ +H ++DL E+ ++L +L + ++Q ++K I + +L Q + + A+L +E+I T Y+ S++ + + + + + ++ + + II Q+F + Y+INA LN LL R D+C +S G+Q++YN+S E W+R + L SGA+Q + P+ +A QLLQ + EDA+ +C +C L+T+Q+VKILN + P + + R++ I I+ Q++ +R D P + L+ + P+ PF + +++ IP L L L
Sbjct: 1 MSVGELYSQCTRVWIPDPDEVWRSAELTKDYKEGDKSLQLRLEDETILEYPIDVQRNQLPFLRNPDILVGENDLTALSYLHEPAVLHNLKVRFLESNHIYTYCGIVLVAINPYEQLPIYGQDVIYTYSGQNMGDMDPHIFAVAEEAYKQMARDEKNQSIIVSGESGAGKTVSAKYAMRYFATVGGSAS-------ETNIEEKVLASSPIMEAIGNAKTTRNDNSSRFGKYIQIGFDKRYHIIGANMRTYLLEKSRVVFQADDERNYHIFYQL---CAAAGLPEFKELALTSAEDFFYTSQGGDTSIEGVDDAEDFEKTRQAFTLLGVKESHQMSIFKIIASILHLGSVAIQAERDGDSCSISPQDVYLSNFCRLLGVEHSQMEHWLCHRKLVTTSETYVKTMSLQQVINARNALAKHIYAQLFGWIVEHINKALHTSLK-----------------QHSFIGVLDIYGFETFEVNSFEQFCINYANEKLQQQFNSHVFKLEQEEYMKEQIPWTLIDFYDNQPCIDLIEAKLGILDLLDEECKVPKGTDQNWAQKLYDRH-SSSQHFQKPRMSNTAFIIVHFADKVEYLSDGFLEKNRDTVYEEQINILKASKFPLVADLFHDDKDPVPATTPGKGSSSKISVRSARPPMKVSN-KEHKKTVGHQFRTSLHLLMETLNATTPHYVRCIKPNDEKLPFHFDPKRAVQQLRACGVLETIRISAAGYPSRWAYHDFFNRYRVLVKKRELANTDKKAICRSVLENLIKDPDKFQFGRTKIFFRAGQVAYLEKLRADKFRTATIMIQKTVRGWLQKVKYHRLKGATLTLQRYCRGHLARRLAEHLRRIRAAVVLQKHYRMQRARQAYQRVRRAAVVIQAFTRAMFVRRTYRQVLMEHKATTIQKHVRGWMARRHFQRLRDAAIVIQCAFRMLKARRELKALRIEARSAEHLKRLNVGMENKVVQLQRKIDEQNKEFKTLSEQLSVTTSTYTMEVERLKKELVHYQQSPGEDTSLRLQEEVESLRTELQRAHSER-KILEDAHSREKDELRKRVADLEQENALLKDEKEQLNNQILCQSKDEFAQNSVKENLMKKELEEERSRYQNLVKEYSQLEQRYDNLRDEMTIIK---QTPG--HRRNPSNQSSLESDSNYPSISTSEIGDTEDALQQVEEIGLE---------------KAAMDMTVFLKLQKRVRELEQERKKLQVQLEKREQQDSKKVQAEPPQTDIDLDPNADLAYNSLKRQELESENKKLKNDLNELRKAVADQATQNNSSHGSPDSYSLLLNQLKLAHEELEVRKEEVLILRTQIVSADQRRLAGRNAEPNINARSSWPNSEKHVDQEDAIEAYHGVCQTNSKT--EDWGYLNEDGELGLAYQGLKQVARLLEAQLQAQSLEHEEEVEHLKAQLEALKEEMDKQQQTFCQTLLLSPEAQVEFGVQQEISRLTNENLDLKELVEKLEKNERKLKKQLKIYMKKAQDLEAAQALAQSERKRHEL----------NRQVTVQRKEKDFQ-GMLEYHKEDEALLIRNLVTDLKPQMLSGTVPC-LPAYILYMCIRHADYTNDDLKVHSLLTSTINGIKKVLKKHNDDFEMTSFWLSNTCRLLHCLKQYSGDEGFMTQNTAKQNEHCLKNFDLTEYRQVLSDLSIQIYQQLIK-IAEGVL-QPMIVSAMLENESIQGLSGVKPTGYRKRSSSMADGDNSYCLEAIIRQMNAFHTVMCDQGLDPEIILQVFKQLFYMINAVTLNNLLLRKDVCSWSTGMQLRYNISQLEEWLRGRNLHQSGAVQTMEPLIQAAQLLQLKKKTQEDAEAICSLCTSLSTQQIVKILNLYTPLNEFEERVTVAFIRTIQAQLQ-ERND-PQQLLLDAKHM--FPVLFPFNPSSLTMDSIHIPACLNLEFL 1845
BLAST of Dach-2 vs. TrEMBL
Match: A0A481MTK7 (Dach-2 OS=Schmidtea mediterranea OX=79327 PE=2 SV=1) HSP 1 Score: 3545.36 bits (9192), Expect = 0.000e+0 Identity = 1830/1851 (98.87%), Postives = 1832/1851 (98.97%), Query Frame = 2
Query: 47 MALYEMYSKGVKIWIPDEESVWIGATVLQFHKEKNVIKIITDNGISKELNLSSKKCAPFLRNPDILIGQKDLTYLSYLNEPEVLYNLQIRFCERREIYTYCGIVLVAINPYQELSIYGKEIINAYHSQNSVDLDPHIFAVAENAFRRMSSFGENQSIIVSGESGAGKTVSAKYTMRYFALVGGSKTKQSFNLTETQIERKVLLSNPILEAFGNAKTIRNDNSSRFGKYLEILFNPRNQVIGANMCTYLLEKSRVVFQNLGERNYHIFYQIVTHCQSEDELLMNTGLVNNVEMYDYLRYGESLEIDGVDDSHEFLITKNSFLQLGIDLNKFKTICEILAAILHLGNIRFRFHDATDSSIIENPELLKLIAGLLGCSIDQLKIWLCFRTISTFQETLHKPLSKAEAQYFRDAFVKTLYSNLFDWIVKQANKVLSTDVSINIKKKLKKTIVVNQEDKKKFIAVLDIYGFETFAENSFEQFCINFANEKLQLQFNLHVFKLEQEEYMNEGLEWTFIDYYNNQPCIDLIESRXXXXXXXXXXXXXXXXSDENWCCKIYSHHLNKSANFNKPKLSNMVFIIEHFAGPVEYKCAGFIEKNRDSVLEEQINLLKASDVQLIAELFRDSEIEIFDTNNXXXXXXXXXXXXXXXXXXQENTRKMKKTVGSQFRNSLKSLMDALNKTNPHYVRCIKPNDLKLPFTFCPERAVQQLRACGVLETIRLSAAGFPSRWTYSDFYHRYYILMSNFNVKNHDFKAGSQKIVETLITVPDAFRFGNTKLFFRPGQVALLEKLRGHKIESSVTLIQSILRGSIERKKYLIIHKLTVQIQTYIRRKLAIEKATKLSQIRAVIIIQSFYRMYLARKLFVKMKCAVLAIEKWRRKIITTRLKQAYKKENCVIICQAIVRRFIQRRKFLKIQRGVILIQNHYRRRKAKETLKILKIEARSINHIKFVNKGLENKIIELTQKLDTKEKEMCXXXXXXXXXXXXXXXXXXXXXAESAKIYQNTVQDLQTEIIQLKKELNREIVEKNKIFADKELLEINYKKKINYLENLIEELKSSPSVIEPNIICNGDEAQQSICQDEHQKFINEQMDHQKLVREYEKLEMKYENLYKEFLFVKSSNQKPSINYDNQTSNDSETESTFSKDDADVESLSDKVDAKTTKEHXXXXXXXXXXLPNFISESISTAGDLAVVMQLQMNISSLSQENNRLKETVQQFEDELLKYEQCAEDSKGLVIHNEYDNELLSIIKDIKGMDEHGLKSRLIDEVANLKKKLKQSNEDYQKLRLHIFDGSMSKLTGNLDHESINSEEEELKRAFESQKEANRKMLKEIEGIKANNVDLKKALFQIRKDKEQLQVQLGKQHLMIRHGVEYLQNLKLTPKERLDKFVQNEISRILLENLKLQERNDQIISETIELKRGLKYFAFRLQKYEGSLVPNPNKEEDLLQLIQNVIYHSKMKTIGKRECYSEIGLIDLNMSELSIFIKSFIFDLSPSICLQYEPYHLVPYIIFMVTRKFDFYKEEDQMTNFLSKLIVALKRTIRKRRNYIEYLVMLLSNVFCLVNLXXXXXXXXXXXXLNTAEDIQHYFVHYDLNEFIRLLKELCVTLFQMILKTIVDNLLPQSLCIDAILVHEAIIDFLSKDGTKYKSNIETQPKNTSFNVLTKNLQSVLEILKNHKIPQLIINQIFVHIAYLINAYCLNTLLFRTDLCYFSKGLQIKYNLSSFETWIRYQKLIDSGALQCLRPMTEAVQLLQTLIDSDEDAKFVCDMCEYLNTRQVVKILNNFNPRDGYGCRLSSGLIAKIETQMKIKRGDEPSESKLETPTVIEIPIDIPFIHNGVSLCRTIIPKPLYLSCLTVLSEKDLL 5599
MALYEMYSKGVKIWIPDEESVWIGATVLQFHKEKNVIKIITDNGISKELNLSSKKCAPFLRNPDILIGQKDLTYLSYLNEPEVLYNLQIRFCERREIYTYCGIVLVAINPYQELSIYGKEIINAYHSQNSVDLDPHIFAVAENAFRRMSSFGENQSIIVSGESGAGKTVSAKYTMRYFALVGGSKTKQSFNLTETQIERKVLLSNPILEAFGNAKTIRNDNSSRFGKYLEILFNPRNQVIGANMCTYLLEKSRVVFQNLGERNYHIFYQIVTHCQSEDELLMNTGLVNNVEMYDYLRYGESLEIDGVDDSHEFLITKNSFLQLGIDLNKFKTICEILAAILHLGNIRFR HDATDSSIIENPELLKLIAGLLGCSIDQLKIWLCFRTISTFQETLHKPLSKAEAQYFRDAFVKTLYSNLFDWIVKQANKVLSTDVSINIKKKLKKTIVVNQEDKKKFIAVLDIYGFETF ENSFEQFCINFANEKLQLQFNLHVFKLEQEEYMNEGLEWTFIDYYNNQPCIDLIESRLGLLDLLDEECKLLKGSDENWCCKIYSHHLNKS NFNKPKLSNMVFIIEHFAGPVEYKCAGFIEKNRDSVLEEQINLLKASDVQLIAELFRDSEIEI DTNNSKPKVSIKSSTKSIMSIKQENTRKMKKTVGSQFRNSLKSLMDALNKTNPHYVRCIKPNDLKLPFTFCPERAVQQLRACGVLETIRLSAAGFPSRWTYSDFYHRYYILMSNFNVKNHDFKAGSQKIVETLITVPDAFRFGNTKLFFRPGQVALLEKLRGHKIESSVTLIQSILRGSIERKKYLIIHKLTVQIQTYIRRKLAIEKATKLSQIRAVIIIQSFYRMYLARKLFVKMKCAVLAIEKWRRKIITTRLKQAYKKENCVIICQAIVRRFIQRRKFLKIQRGVILIQNHYRRRKAKETLKILKIEARSINHIKFVNKGLENKIIELTQKLDTKEKEMCLIQNQLIKEKKIEILNLKLNQAESAKIYQNTVQDLQTEIIQLKKELNREIVEKNKIFADKELLEINYKKKINYLENLIEELKSSPSVIEPNIICNGDEAQQSICQDEHQKFINEQMDHQKLVREYEKLEMKYENLYKEFLFVKSSNQKPSINYDNQTSNDSETESTFSKDDAD ESLSD+VDAKTTKEHVVKSSVVVKKLPNFISESISTAGDLAVVMQLQMNISSLSQENNRLKETVQQFEDELLKYEQCAEDSKGLVIHNEYDNELLSIIKDIKGMDEHGLKSRLIDEVANLKKKLKQS EDYQKLRLHIFDGSMSKL GNLDHESINSEEEELKRAFESQKEANRKMLKEIEGIKANNVDLKKALFQIRKDKEQLQVQLGK +I NLKLTPKERLDKFVQNEISRILLENLKLQERNDQI SETIELKRGLKYFAFRLQKYEGSLVPNPNKEEDLLQLIQNVIYHSKMKTIGKRECYSEIGLIDLNMSELSIFIKSFIFDLSPSICLQYEPYHLVPYIIFMVTRKFDFYKEEDQMTNFLSKLIVALKRTIRKRRNYIEYLVMLLSNVFCLVNLFQQYSGSQQFSGLNTAEDIQHYFVHYDLNEFIRLLKELCVTLFQMILKTIVDNLLPQSLCIDAILVHEAIIDFLSKDGTKYKSNIETQPKNTSFNVLTKNLQSVLEILKNHKIPQLIINQIFVHIAYLINAYCLNTLLFRTDLCYFSKGLQIKYNLSSFETWIRYQKLIDSGALQCLRPMTEAVQLLQTLIDSDEDAKFVCDMCEYLNTRQVVKILNNFNPRDGYGCRLSSGLIAKIETQMKIKRGDEPSESKLETPTVIEIPIDIPFIHNGVSLCRTIIPKPLYLSCLTVLSEKDLL
Sbjct: 1 MALYEMYSKGVKIWIPDEESVWIGATVLQFHKEKNVIKIITDNGISKELNLSSKKCAPFLRNPDILIGQKDLTYLSYLNEPEVLYNLQIRFCERREIYTYCGIVLVAINPYQELSIYGKEIINAYHSQNSVDLDPHIFAVAENAFRRMSSFGENQSIIVSGESGAGKTVSAKYTMRYFALVGGSKTKQSFNLTETQIERKVLLSNPILEAFGNAKTIRNDNSSRFGKYLEILFNPRNQVIGANMCTYLLEKSRVVFQNLGERNYHIFYQIVTHCQSEDELLMNTGLVNNVEMYDYLRYGESLEIDGVDDSHEFLITKNSFLQLGIDLNKFKTICEILAAILHLGNIRFRSHDATDSSIIENPELLKLIAGLLGCSIDQLKIWLCFRTISTFQETLHKPLSKAEAQYFRDAFVKTLYSNLFDWIVKQANKVLSTDVSINIKKKLKKTIVVNQEDKKKFIAVLDIYGFETFEENSFEQFCINFANEKLQLQFNLHVFKLEQEEYMNEGLEWTFIDYYNNQPCIDLIESRLGLLDLLDEECKLLKGSDENWCCKIYSHHLNKSVNFNKPKLSNMVFIIEHFAGPVEYKCAGFIEKNRDSVLEEQINLLKASDVQLIAELFRDSEIEILDTNNSKPKVSIKSSTKSIMSIKQENTRKMKKTVGSQFRNSLKSLMDALNKTNPHYVRCIKPNDLKLPFTFCPERAVQQLRACGVLETIRLSAAGFPSRWTYSDFYHRYYILMSNFNVKNHDFKAGSQKIVETLITVPDAFRFGNTKLFFRPGQVALLEKLRGHKIESSVTLIQSILRGSIERKKYLIIHKLTVQIQTYIRRKLAIEKATKLSQIRAVIIIQSFYRMYLARKLFVKMKCAVLAIEKWRRKIITTRLKQAYKKENCVIICQAIVRRFIQRRKFLKIQRGVILIQNHYRRRKAKETLKILKIEARSINHIKFVNKGLENKIIELTQKLDTKEKEMCLIQNQLIKEKKIEILNLKLNQAESAKIYQNTVQDLQTEIIQLKKELNREIVEKNKIFADKELLEINYKKKINYLENLIEELKSSPSVIEPNIICNGDEAQQSICQDEHQKFINEQMDHQKLVREYEKLEMKYENLYKEFLFVKSSNQKPSINYDNQTSNDSETESTFSKDDADFESLSDEVDAKTTKEHVVKSSVVVKKLPNFISESISTAGDLAVVMQLQMNISSLSQENNRLKETVQQFEDELLKYEQCAEDSKGLVIHNEYDNELLSIIKDIKGMDEHGLKSRLIDEVANLKKKLKQSTEDYQKLRLHIFDGSMSKLAGNLDHESINSEEEELKRAFESQKEANRKMLKEIEGIKANNVDLKKALFQIRKDKEQLQVQLGKLGDLI-------GNLKLTPKERLDKFVQNEISRILLENLKLQERNDQITSETIELKRGLKYFAFRLQKYEGSLVPNPNKEEDLLQLIQNVIYHSKMKTIGKRECYSEIGLIDLNMSELSIFIKSFIFDLSPSICLQYEPYHLVPYIIFMVTRKFDFYKEEDQMTNFLSKLIVALKRTIRKRRNYIEYLVMLLSNVFCLVNLFQQYSGSQQFSGLNTAEDIQHYFVHYDLNEFIRLLKELCVTLFQMILKTIVDNLLPQSLCIDAILVHEAIIDFLSKDGTKYKSNIETQPKNTSFNVLTKNLQSVLEILKNHKIPQLIINQIFVHIAYLINAYCLNTLLFRTDLCYFSKGLQIKYNLSSFETWIRYQKLIDSGALQCLRPMTEAVQLLQTLIDSDEDAKFVCDMCEYLNTRQVVKILNNFNPRDGYGCRLSSGLIAKIETQMKIKRGDEPSESKLETPTVIEIPIDIPFIHNGVSLCRTIIPKPLYLSCLTVLSEKDLL 1844
BLAST of Dach-2 vs. TrEMBL
Match: V4ACD4 (Uncharacterized protein (Fragment) OS=Lottia gigantea OX=225164 GN=LOTGIDRAFT_122399 PE=3 SV=1) HSP 1 Score: 1169.07 bits (3023), Expect = 0.000e+0 Identity = 732/1885 (38.83%), Postives = 1076/1885 (57.08%), Query Frame = 2
Query: 77 VKIWIPDEESVWIGATVLQFHKEKNVIKIITDNGISKELNLSSKKCAPFLRNPDILIGQKDLTYLSYLNEPEVLYNLQIRFCERREIYTYCGIVLVAINPYQELSIYGKEIINAYHSQNSVDLDPHIFAVAENAFRRMSSFGENQSIIVSGESGAGKTVSAKYTMRYFALVGGSKTKQSFNLTETQIERKVLLSNPILEAFGNAKTIRNDNSSRFGKYLEILFNPRNQVIGANMCTYLLEKSRVVFQNLGERNYHIFYQIVTHCQSEDELLMNTGLVNNVEMYDYLRYGESLEIDGVDDSHEFLITKNSFLQLGIDLNKFKTICEILAAILHLGNIRFRFHDATDSSIIENPELLKLIAGLLGCSIDQLKIWLCFRTISTFQETLHKPLSKAEAQYFRDAFVKTLYSNLFDWIVKQANKVLSTDVSINIKKKLKKTIVVNQEDKKKFIAVLDIYGFETFAENSFEQFCINFANEKLQLQFNLHVFKLEQEEYMNEGLEWTFIDYYNNQPCIDLIESRXXXXXXXXXXXXXXXXSDENWCCKIYSHHLNKSANFNKPKLSNMVFIIEHFAGPVEYKCAGFIEKNRDSVLEEQINLLKASDVQLIAELFRDSEIEIFDTNNXXXXXXXXXXXXXXXXXXQENTRKMKKTVGSQFRNSLKSLMDALNKTNPHYVRCIKPNDLKLPFTFCPERAVQQLRACGVLETIRLSAAGFPSRWTYSDFYHRYYILMSNFNVKNHDFKAGSQKIVETLITVPDAFRFGNTKLFFRPGQVALLEKLRGHKIESSVTLIQSILRGSIERKKYLIIHKLTVQIQTYIRRKLAIEKATKLSQIRAVIIIQSFYRMYLARKLFVKMKCAVLAIEKWRRKIITTRLKQAYKKENCVIICQAIVRRFIQRRKFLKIQRGVILIQNHYRRRKAKETLKILKIEARSINHIKFVNKGLENKIIELTQKLDTKEKEMCXXXXXXXX-XXXXXXXXXXXXXAESAKIYQNTVQDLQTEIIQLKKELNREIVEKNKIFADKELLEINYKKKINYLENLIEELKSSPSVIEPNIICNGDEAQQSICQDEH-------QKFINEQMDHQKLVREYEKLEMKYENLYKEFLFVKSSNQKPSINYDNQTSNDSETESTFSKDDADVESLSDKVDAKTTKEHXXXXXXXXXXLPNFISESISTAGDLAVVMQLQMNISSLSQENNRLKETVQQFEDELLKYEQCAEDSKGLV------------IHNEYD------NELLSIIKDIKGMDEHG-----LKSRLIDEVANLKKKLKQSNEDYQKLRLHIFDGSMSKLTGNLDHESINS------EEEELKRAFESQKEANRKMLKEIEGIKAN----NVDLKKALFQIRKDKEQLQVQLGKQHLMIRHGVEYLQNLKLTPKERLDKFVQNEISRILLENL---------KLQERNDQIISETIELKRGLKYFAFRLQKYEGSLVPNPNKEEDLLQLIQNVIYHSKMKTIGKRECYSEIGLIDLNMSELSIFIKSFIFDLSPSICLQYEPYHLVPYIIFMVTRKFDFYKEEDQMTNFLSKLIVALKRTIRKRRNYIEYLVMLLSNVFCLVNLXXXXXXXXXXXXLNTAEDIQHYFVHYDLNEFIRLLKELCVTLFQMILKTIVDNLLPQSLCIDAILVHEAIIDFLSKDGTKYKSNI-----ETQPKNTSFNVLTKNLQSVLEILKNHKIPQLIINQIFVHIAYLINAYCLNTLLFRTDLCYFSKGLQIKYNLSSFETWIRYQKLIDSGALQCLRPMTEAVQLLQTLIDSDEDAKFVCDMCEYLNTRQVVKILNNFNPRDGYGCRLSSGLIAKIETQMKIKRGDEPSESKLETPTVIEIPIDIPFIHNGVSLCRTIIPKPLYLS 5566
+IWIPD E+VW A +L+ + + I + L++ K P LRNPDILIG+ DLT LSYLNEPEVLYNL++RF E IYTYCGIVLVAINPY++L IY +II+AY Q+ +DPHIFAVAE AF++MS F NQSIIVSGESGAGKTVSAKY MRYFA VGGS+T ETQ+E+KVL SNPI+EA GNAKT RNDNSSRFGKY+E+ F+ N +IGANM TYLLEKSRVVFQ ERNYHIFYQ+ C S + + + + Y G + EI+ VDD+ + T+ + LG+ + +I +ILAAILH GN+ R + I +N + LK++ LL Q+KIWLC R I+T E L+KPL++++A+ RDA K +YSNLF+WIV Q NK L + + +FI VLDIYGFETF NSFEQFCIN+ANEKLQ FN+HVFKLEQEEY+ E +EW+FID+Y+NQPCIDLIES+LG+LDLLDEECK+ +GSD NWC K+Y HL KS +FNKP++S F+I HFA V Y GF+EKNRD+VLEEQIN+LKAS+++L+ ELF + K K I + +++ KKTVGSQFR+SL LM LN T PHY+RCIKPND K FTF +RAV+QLRACGVLETIR+SAAG+PSRWTY +F+ RY +L + + + + I+ LI D +RFG +K+FFR GQVA LEKLR K+ + +IQ +RG + R+KY I K + +Q Y R LA A L Q A +IQ ++ Y RK + K++ + ++ R + R + K + I Q VR F+ +R++ + RG+IL+Q+HYRRRKA+ LKILK+EA+S++H+K VNKGLENKIIEL QKLD K KE+ ++ + K + + E A+ N + +L EI +LK EL E EK + ++KEL++ ++ K I+ + E++K+ ++ + + EA+ S +F +E+ HQKLV+E+ +L+ ++ENL E V S + T S S +ES S DA+ + D+++V++LQ + L +E L+E + ++ED+ L + E+S L + NE D L++ I + +D+ + ++ + +L + E+ +LR + D ++S T ++ ES + E++EL A+++QK+ NR + +++ + + +L+K + +++KD E+ Q +G QNL L P+ +++ +Q+EI+R+ ENL L+E D + +LK+ LK ++ +L+ E L N E + + T+ RE + +G+++L + + IK+ + DL P + P L YI+FM+ R+ DF +++++ L+ I +K+ +++ + ++ + + L+N L++ +QYSG + F N+ + + ++DL+E+ ++ +L V ++Q +LK + + + P + AIL HEAI + + + E + S + L ++L + + I+ H + + QIF + Y I A LN LL R D+C +SKG+QI+YNLS E W+R KL +SGA+ L P+ +A QLLQ +D D + +MC L Q+VKILN + P D + R+ I KI Q K+K D+ + + L T P+ PF + + L +P L++S
Sbjct: 1 ARIWIPDVENVWRAAELLEDYTGQKTTAIKYEEAEESTLDID-KNNLPHLRNPDILIGENDLTSLSYLNEPEVLYNLRVRFLESNLIYTYCGIVLVAINPYEQLDIYSNDIIHAYSGQDMGAMDPHIFAVAEEAFKQMSRFERNQSIIVSGESGAGKTVSAKYAMRYFATVGGSQT-------ETQVEKKVLASNPIMEAIGNAKTTRNDNSSRFGKYIELGFSRSNSIIGANMRTYLLEKSRVVFQAQDERNYHIFYQM---CASAHIPEFKKMELQHADDFFYTSQGGAPEINDVDDAKDLNSTREALSILGLSEQQQMSIFQILAAILHFGNVSIREGEGETCEIPDNDQSLKMMCKLLAIEESQMKIWLCNRKITTVNEVLNKPLTESQAKDSRDALAKHIYSNLFNWIVTQVNKALHS-----------------TSKQHRFIGVLDIYGFETFEINSFEQFCINYANEKLQQIFNMHVFKLEQEEYVREQIEWSFIDFYDNQPCIDLIESKLGILDLLDEECKMPRGSDSNWCQKLYDKHLGKSKHFNKPRMSRTAFVIIHFADQVTYTADGFLEKNRDTVLEEQINILKASEIELVGELFSEG------------GEGKKGREKPIKQQPKAGSKQHKKTVGSQFRDSLSLLMATLNATTPHYIRCIKPNDEKCAFTFDSKRAVEQLRACGVLETIRISAAGYPSRWTYPEFFQRYRVLAKTKQIIKGNMRKTCESILPDLIADEDKYRFGKSKIFFRAGQVAYLEKLRSDKLRACGIMIQKHIRGWLLRRKYSKIRKSALLLQCYGRGLLARRHAQYLRQTHAATVIQKTWKGYKDRKQYSKLRTTMCVLQACIRGLFARRKYASLLKNHKAKIIQRHVRTFLAKRRYKHVLRGIILLQSHYRRRKARTKLKILKVEAKSVDHVKKVNKGLENKIIELQQKLDQKAKEVVEVKQEEAKIVQLKSEITKLKENKEVAQDSSNKITELLAEIQRLKAELETERGEKQDLISEKELMKKDHNKIIDEVLEEKEKIKNQLNLAQEKL----KEAESSTADKLEAANKLLLAEFESERSHHQKLVKEHARLQQRFENLQGELEIVTSP------------TGHKRTPSDISA--VSIESYSSSADAERNN--------------EEKEKEEEAEVDVSLVLKLQNKVKELEKERQHLQERIDRYEDKRLDEQNIEEESHFLGGDMAFQSLKMQELENENDKLKREVTRLMNAIAESTDLDDRSGELSPTGKKFMERYDAMGDELDRRREECLQLRAMLADRTIS--THSIAKESYSGQDNLVNEDDELSMAYKTQKDLNRLLQSQLDKTEKDAKRIQDELRKEIKELKKDNERQQKLIG-------------QNLSLGPEAKIEATMQHEITRLTSENLVSLMSILLCDLREMIDDQTQQIRKLKKVLKVYSKKLRAGEAELDRAENGEGN-----------GSLATVKHRE-RTFMGMLELKKDDENTLIKNLVLDLKPKVAAGLIP-GLPAYILFMIVRQTDFTNDDEKVRGLLTNTINGIKKVVKRHNDDLDRITLWLANTCRLLHTLKQYSGEKAFQPENSTKQNEQCLRNFDLSEYRQVFSDLAVWIYQGLLKRMEELIQPS--IVPAILEHEAISGLNASKPSGLRGRSSSSARELDSNDYSLDSLMRSLNNYMRIVTQHAVDPELGKQIFRQVFYYICAGSLNNLLLRKDMCNWSKGMQIRYNLSHLEQWLRDNKLSESGAITALDPIIQASQLLQAR-KTDSDVDSISEMCSKLTNAQIVKILNLYTPVDEFEERVPISFIRKI--QEKLKSRDDTNNTLL-MDTKYSYPVTFPFNPSNIQLETIEVPDILHIS 1779
BLAST of Dach-2 vs. TrEMBL
Match: A0A2T7PSZ8 (Uncharacterized protein OS=Pomacea canaliculata OX=400727 GN=C0Q70_03491 PE=3 SV=1) HSP 1 Score: 1143.26 bits (2956), Expect = 0.000e+0 Identity = 735/1903 (38.62%), Postives = 1100/1903 (57.80%), Query Frame = 2
Query: 59 EMYSKGVKIWIPDEESVWIGATVLQFHKEKNVIKIITDNGISKELNLSSKKCAPFLRNPDILIGQKDLTYLSYLNEPEVLYNLQIRFCERREIYTYCGIVLVAINPYQELSIYGKEIINAYHSQNSVDLDPHIFAVAENAFRRMSSFGENQSIIVSGESGAGKTVSAKYTMRYFALVGGSKTKQSFNLTETQIERKVLLSNPILEAFGNAKTIRNDNSSRFGKYLEILFNPRNQVIGANMCTYLLEKSRVVFQNLGERNYHIFYQIVTHCQSEDELLMNTGLVNNVEMYDYLRYGESLEIDGVDDSHEFLITKNSFLQLGIDLNKFKTICEILAAILHLGNIRFRFHDATDSSIIENPELLKLIAGLLGCSIDQLKIWLCFRTISTFQETLHKPLSKAEAQYFRDAFVKTLYSNLFDWIVKQANKVLSTDVSINIKKKLKKTIVVNQEDKKKFIAVLDIYGFETFAENSFEQFCINFANEKLQLQFNLHVFKLEQEEYMNEGLEWTFIDYYNNQPCIDLIESRXXXXXXXXXXXXXXXXSDENWCCKIYSHHLNKSANFNKPKLSNMVFIIEHFAGPVEYKCAGFIEKNRDSVLEEQINLLKASDVQLIAELFRDSEIEIFDTNNXXXXXXXXXXXXXXXXXXQE---NTRKMKKTVGSQFRNSLKSLMDALNKTNPHYVRCIKPNDLKLPFTFCPERAVQQLRACGVLETIRLSAAGFPSRWTYSDFYHRYYILMSNFNVKNHDFKAGSQKIVETLITVPDAFRFGNTKLFFRPGQVALLEKLRGHKIESSVTLIQSILRGSIERKKYLIIHKLTVQIQTYIRRKLAIEKATKLSQIRAVIIIQSFYRMYLARKLFVKMKCAVLAIEKWRRKIITTRLKQAYKKENCVIICQAIVRRFIQRRKFLKIQRGVILIQNHYRRRKAKETLKILKIEARSINHIKFVNKGLENKIIELTQKLDTKEKEMCXXXXXXXXXXXXXXXXXXXXXA-ESAKIYQNTVQDLQTEIIQLKKELNREIVEKNKIFADKELLEINYKKKINYLENLIEE--------------LKSSPSVIEPNIICNGDEAQQSICQDEHQKFINEQMDHQKLVREYEKLEMKYENLYKEFLFVKSSNQKPSINYDNQTSNDSETESTFSKDDADVESLSDKVDAKTTKEHXXXXXXXXXXLPNFISESISTA--------GDLAVVMQLQMNISSLSQENNRLKETVQQFEDELLKYEQ-----CAEDS-KGLVIHNEYD---NELLSIIKDIKGMDEHG--------LKSRLIDEVANLKKKLKQSNEDYQKLRLHIFD-----GSMSKLT-GNLDHESINSEEEELKRAFESQKEANRKMLKEIEGI----KANNVDLKKALFQIRKDKEQLQVQLGKQHLMIRHGVEYLQNLKLTPKERLDKFVQNEISRILLENLKLQERNDQIISETIELKRGLKYFAFRLQKYEGSLVPNPNKEEDLLQLIQNVIYHSKMKTIGKRECYSEIGLIDLNMSELSIFIKSFIFDLSPSICLQYEPYHLVPYIIFMVTRKFDFYKEEDQMTNFLSKLIVALKRTIRKRRNYIEYLVMLLSNVFCLVNLXXXXXXXXXXXXLNTAEDIQHYFVHYDLNEFIRLLKELCVTLFQMILKTIVDNLLPQSLCIDAILVHEAIIDFLSKDGTKYKSNIETQPKNT--------SFNVLTKNLQSVLEILKNHKIPQLIINQIFVHIAYLINAYCLNTLLFRTDLCYFSKGLQIKYNLSSFETWIRYQKLIDSGALQCLRPMTEAVQLLQTLIDSDEDAKFVCDMCEYLNTRQVVKILNNFNPRDGYGCRLSSGLIAKIETQMKIKRGDEPSESK-LETPTVIEIPIDIPFIHNGVSLCRTIIPKPLYLSCLTVL 5581
E Y KG +IWIPD + +W A +L+ +K +N IKI + G +++S K P LRNP+ILIG+ DLT LSYLNEPEVLYNL++RF E+ IYTYCGIVLVAINPY+ L IYG +II+AY Q+ +DPHI+AVAE AF++MS F +NQSIIVSGESGAGKTVSAKY MRYFA+VGGS+ + +TQ+E KVL SNPI+EA GNAKT RNDNSSRFGKY+EI FN ++ +IGANM TYLLEKSRVVFQ ERNYHIFYQ+ C S D+ + + + + Y G + I GVDD+ E T+ +F LG I +I++AILH GN+ + I N + L LLG Q+++WLC R I T ETL KPLS+++A + RDA VK +YS +FDWIV NK L + V ++ KFI VLDIYGFETF NSFEQFCIN+ANEKLQ FN+HVFKLEQEEY+ E +EW+FID+Y+NQPCIDLIES+LG+LDLLDEECK+ KGSD NWC K+Y HL KS +F+KP+ SNM FII HFA VEY+ GF+EKNRD+VLEEQ+N+LKAS+ +L+AELF + + +S ++S+ S IK + +++ KKTVGSQFR SL LM+ LN T PHY+RCIKPND K F+ WTY++F+ RY +L + + ++ + + I+ TLI + +RFG TK+FFR GQVA LEKLRG K+++ +IQ +RG ++R+KY IH+ + +QTY R LA KA L + +A I IQ+ +R Y RK + + A++ ++ R R + +E+ ++ QA +R F+ RRKF + RG+IL+Q+HYRRRKA+ LK+LKIEA+S+ HIK VNKGLENKIIEL QKLD + KE+ ++++Q K++++ +L + E AK+ N V DL+ E+ +L+ EL E+V + + A +E +E+ K+ L +++EE +K S E + + A++ + Q+ F E+ HQ+LV+E+ +L+ + ENL E + S P+ ++ S+ S + AD E D D + + V+K+P+F +S + D+ ++++LQ + L ++ RL E ++++EDE E A D+ K + NE D E+ ++K I G +D+ + +L++ E+ +LR + D S++K + G D I +E+ EL+ A+++QK+ NR + ++E + K + ++ L ++RK+ E+ Q +G Q+L L P+ +++ +Q+EI+R+ ENL L+E D+ + +LK+ LK +A +L+ E + + ++++ ++ + T+ RE + +G+ + + IK+ I +L P + P L Y++FM R D+ ++D++ L+ I +K+ ++K + +E + + L+N L++ +QYSG +QF N + ++DL+E+ ++ +L + ++Q ++K + + L P + AIL HEAI + + + + ++ S + L + L S + IL H + ++ QIF + Y + A LN LL R D+C +SKG+QI+YNLS E W+R KL +SGA L P+ +A QLLQ +D D + +C+MC L Q++KILN + P D + R+ I KI++++K + + S L T P+ PF + + L +P+ L+L L L
Sbjct: 71 ECYIKGARIWIPDPDHIWRAAELLEDYKGQNKIKIQYEEGEESAISISDTKL-PHLRNPEILIGENDLTSLSYLNEPEVLYNLKVRFLEQNLIYTYCGIVLVAINPYEYLEIYGNDIIHAYSGQDMGAMDPHIYAVAEEAFKQMSRFEQNQSIIVSGESGAGKTVSAKYAMRYFAMVGGSQADE-----QTQVEAKVLASNPIMEAIGNAKTTRNDNSSRFGKYIEISFNKQHAIIGANMRTYLLEKSRVVFQASEERNYHIFYQL---CDSADDPEYEKFELGSADDFFYTSQGGAPVIKGVDDAAELKRTREAFTMLGFSGKNQMLILQIISAILHFGNVHISEKEGEACEIPANDKALTTTCKLLGIQESQMRMWLCHRKIETVGETLTKPLSESQAAFGRDALVKHIYSRVFDWIVTHINKNLRSTVKVH-----------------KFIGVLDIYGFETFQVNSFEQFCINYANEKLQQIFNMHVFKLEQEEYVREAIEWSFIDFYDNQPCIDLIESKLGILDLLDEECKMPKGSDANWCQKLYDKHLKKSKHFDKPRTSNMAFIINHFADRVEYQAEGFLEKNRDTVLEEQVNILKASEFELVAELFTEEDNMGGSQGSSAAHGRKRTSSTSTQPIKAQPKGASKQHKKTVGSQFRESLHLLMETLNATTPHYIRCIKPNDSKESFS-----------------------------WTYAEFFQRYRVLATFKLIVKNNMRKTCEAILPTLIADEEKYRFGKTKIFFRAGQVAYLEKLRGDKLKACGVMIQKHIRGWLQRRKYRRIHRSALLLQTYGRGLLARRKALYLRRTKAAINIQTMWRCYRERKAYRETFKAIVVLQAHIRAQFARRQYRGLLEEHKAVLIQAHIRAFLMRRKFRLVLRGIILVQSHYRRRKARLQLKLLKIEAKSVEHIKVVNKGLENKIIELQQKLDERAKELNVLKDQETTMKQLKVEMERLKSSDEVAKVSSNKVLDLEDELARLRAEL--EVVTRERDRAVREKIEM-MKENEEVLTSILEEKMSLKEQLEEANRRIKLQESNSEDFVKDQVEAAKRGLIQE----FEAERSHHQRLVKEHARLQQRLENLQGEMQVLTS----PTGHHHRTPSDISAISTESFASSADTEKRED--DEDQGYDTAKRKGEAVRKVPSFSEKSPAERLAPKKTEDVDVGLLLKLQNKVKDLEKDRARLLERLEKYEDEGGPGESGFIRDSAFDALKMQELENEKDKLKREVERLMKSIAATTNFGDNGGQVSPAAKEFLDQFEAMTDELERRREECLQLRAMMADRMITMHSIAKESYGGQD--DIVNEDNELEMAYKTQKDLNRLLQNQLENVEKELKRKDKAYQQELVELRKENERQQKLIG-------------QSLTLGPEAKIEATMQHEITRMTAENLDLRETIDKQSEQIRKLKKMLKIYAKKLKDGEAAEIAAELEQDE-----KDKGGATMGATVKLRE-RTYMGMFEYRREDEGALIKNLILELKPKVAAGLIP-GLPSYVLFMCVRHTDYINDDDKVKALLTGTINGIKKVVKKHTDDLERVTLWLANTCRLMHTLKQYSGDKQFQVDNQPRQNEMCLRNFDLSEYRQVFSDLAIWIYQTLIKFMQELLQPS--IVPAILEHEAIAGLTASKPSGLRGRSSSNARDLDDGKEDAHSLDALMRTLNSYMRILTQHAVDPELVKQIFRQLYYFMCAGALNNLLLRKDMCNWSKGMQIRYNLSHMEQWLRDNKLQESGAQLALDPIVQASQLLQAR-KTDSDVESICEMCSKLTIAQIIKILNLYTPVDEFEERVPISFIRKIQSRLKSRPDAAAAGSNTLLMDTKFTYPVTFPFNPSSILLDSVEVPEQLHLGFLKKL 1880
BLAST of Dach-2 vs. TrEMBL
Match: A0A0F7VJF0 (Eka-NinaC protein (Fragment) OS=Euperipatoides kanangrensis OX=488523 GN=Eka-NinaC PE=2 SV=1) HSP 1 Score: 1131.32 bits (2925), Expect = 0.000e+0 Identity = 738/1907 (38.70%), Postives = 1089/1907 (57.11%), Query Frame = 2
Query: 47 MALYEMYSKGVKIWIPDEESVWIGATVLQFHKEKNVIKIITDNGISKELNLSSKKCAPFLRNPDILIGQKDLTYLSYLNEPEVLYNLQIRFCERREIYTYCGIVLVAINPYQELSIYGKEIINAYHSQNSVDLDPHIFAVAENAFRRMSSFGENQSIIVSGESGAGKTVSAKYTMRYFALVGGSKTKQSFNLTETQIERKVLLSNPILEAFGNAKTIRNDNSSRFGKYLEILFNPRNQVIGANMCTYLLEKSRVVFQNLGERNYHIFYQIVTHCQSEDELLMNTGLVNNVEMYDYLRYGESLEIDGVDDSHEFLITKNSFLQLGIDLNKFKTICEILAAILHLGNIRF--RFHDATDSSIIENPELLKLIAGLLGCSIDQLKIWLCFRTISTFQETLHKPLSKAEAQYFRDAFVKTLYSNLFDWIVKQANKVLSTDVSINIKKKLKKTIVVNQEDKKKFIAVLDIYGFETFAENSFEQFCINFANEKLQLQFNLHVFKLEQEEYMNEGLEWTFIDYYNNQPCIDLIESRXXXXXXXXXXXXXXXXSDENWCCKIY-----SHHLNKSANFNKPKLSNMVFIIEHFAGPVEYKCAGFIEKNRDSVLEEQINLLKASDVQLIAELFRDSEIEIFDTNNXXXXXXXXXXXXXXXXXXQENTRKMKKTVGSQFRNSLKSLMDALNKTNPHYVRCIKPNDLKLPFTFCPERAVQQLRACGVLETIRLSAAGFPSRWTYSDFYHRYYILMSNFNVKNHDFKAGSQKIVETLITVPDAFRFGNTKLFFRPGQVALLEKLRGHKIESSVTLIQSILRGSIERKKYLIIHKLTVQIQTYIRRKLAIEKATKLSQIRAVIIIQSFYRMYLARKLFVKMKCAVLAIEKWRRKIITTRLKQAYKKENCVIICQAIVRRFIQRRKFLKIQRGVILIQNHYRRRKAKETLKILKIEARSINHIKFVNKGLENKIIELTQKLDTKEKEMCXXXXXXXXXXXXXXXXXXXXXAESAKIYQNTVQDLQTEIIQLKKELNREIVEKNKIFADKELLEINYKKKINYLENLIEELKSSPSVIEPNIICNGDEAQQ---SICQDE---HQKFINEQMDHQKLVREYEKLEMKYENLYKE-----------------FLFVKSSNQKPSIN--YDNQTSNDSETESTFSKDD--ADVESLSDKVDAKTTKEHXXXXXXXXXXLPNFISESISTAGDLAVVMQLQMNISSLSQENNRLKETVQQFEDELLKYEQCAEDSKGLVIHN-EYDN-ELLSIIKDIKGMDEHGLKSR----LIDEVANLKKKLKQSNEDYQKLRLHIFDGSM-----SKLTGNLDHESINSEEEELKRAFESQKEANRKMLKEIEGIKANNV----DLKKALFQIRKDKEQLQVQLGKQHLMIRHGVEYLQNLKLTPKERLDKFVQNEISRILLENLKLQERNDQIISETIELKRGLKYFAFRL------QKYEGSLVPNPNKEEDLLQLIQNVIYHSKMKTIGKRECYSEIGLIDLNMSELSIFIKSFIFDLSPSICLQYEPYHLVPYIIFMVTRKFDFYKEEDQMTNFLSKLIVALKRTIRKRRNYIEYLVMLLSNVFCLVNLXXXXXXXXXXXXLNTAEDIQHYFVHYDLNEFIRLLKELCVTLFQMILKTIVDNLLPQSLCIDAILVHEAIIDFLSKD--GTKYKSNIETQPKNTSFNVLTKNLQSVLEILKN--------HKIPQLIINQIFVHIAYLINAYCLNTLLFRTDLCYFSKGLQIKYNLSSFETWIRYQKLIDSGALQCLRPMTEAVQLLQTLIDSDEDAKFVCDMCEYLNTRQVVKILNNFNPRDGYGCRLSSGLIAKIETQMKIKRGDEPSESKLETPTVIEIPIDIPFIHNGVSLCRTIIPKPLYLSCL 5572
M E+Y KG +W+PD VW A + + K +++ ++G + L + +K P LRNP ILIG+ DLT LSYL+EP VLYNLQ+RF +R IYTYCGIVLVAINPY++L IYG + I Y Q DLDPHIFAVAE A+ +M NQSIIVSGESGAGKTVSAKY MRYFA VGGS ET IE+KVL SNPI+EA GNAKT RNDNSSRFGKY+EI FN + +IGANM TYLLEKSRVVFQ ERNYHIFYQ+ C S D+ + +++ + + Y GES I +DD+H F T+++F LG D + I ILAA+LH GN+ ++ S I ++ L ++ LL DQ+++WLC R +T E L KPLS ++A + RDA K +Y+ LF+WIV NK L+ KFI VLDIYGFETF NSFEQFCIN+ANEKLQ QFN HVFKLEQEEYM E +EW+ ID+Y+NQPCIDLIES+LG+LDLLDEECK+ KG+D WC K++ SHH F KP+LSN FII HFA V+Y+C GF+EKNRD+V+EEQ+N+LKAS + L+ ELF + + + + + + + KKTVGSQFR+SL LM+ LN T P YVRCIKPND KL FTF P+RA+QQLRACGVLETIR+SAAG+PSRWTY +F++RY +L ++K +D K I+E +I D ++FG TK+FFR GQVA LEKLR K+ + LIQ +RG + R +Y + +QIQ YIR LA A L + +A I IQ + R Y K + ++ ++++++ + R + + + I Q VR ++ R K+ K + ++L+Q+ RR A+ LK LKIEARS+ H+K +N+GLENKII L QK+D KE +++ + K++ L K + + L+ EI+ L+ +L E EK +I +KE I +K + ELK + I E ++ S + E H +F +E++++QK++++Y +LE ++ENL E + ++S+ +P+ N DN+ T S + +D +E++ + ++ KE K + + D+ +V++LQ I L N RL++ ++ +D + + L I + E +N +L I+ E G K + ++D+ + L+ +L++ ++ +LR + + S+ SK + E IN E+ EL + + +Q++ R++ KE++G K N DL+K + ++R+D E+ +Q L+ + + +L+++P+ + + +Q+EI+R+ ENL LQE+ D+ +LK+ LK +A +L Q SL+ D+ ++ + M + +E + +G+ + IKS I DL PSI + P L YI+FM R D+ +++++ + L+ I +KR I+K+ E +V+ L+N+ L++ +QYSG + F NT + + ++DL+E+ ++L ++ V ++Q I+K + + + P + AIL HEAI K G + +S TQ +NTS K+L S+ + L N P+ II+QIF I Y I A LN LL R DLC++SKG+Q++YN S E W+R KL + GA++ L P+ +A QLLQ +DED +CDMC+ L Q++K+LN + P D + R+ I KI+ +++ +RG+ + ++T P+ PF + V L IP+ L +S L
Sbjct: 4 MTTAELYVKGAGVWVPDPSLVWKAAVLAEDFKNTKKLEVAYEDGSKEILEVKNKDKLPPLRNPQILIGENDLTSLSYLHEPAVLYNLQVRFVDRNAIYTYCGIVLVAINPYEQLPIYGLDTIMLYRGQAMGDLDPHIFAVAEEAYTKMEREERNQSIIVSGESGAGKTVSAKYAMRYFATVGGS-------TAETNIEKKVLASNPIMEAIGNAKTTRNDNSSRFGKYIEINFNKQYHIIGANMRTYLLEKSRVVFQAPEERNYHIFYQL---CASFDQEDIKELQLSHQDNFLYTNQGESPNIHNIDDAHSFEETRSAFKLLGFDDDVQMNIFRILAAVLHFGNVNIIESEKESDQSRISKDDNHLSILCKLLAIDEDQMRMWLCRRKFTTVNEVLTKPLSVSQAMFSRDALAKHIYAQLFNWIVAGINKSLAFTAKAF-----------------KFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNQHVFKLEQEEYMKEAIEWSLIDFYDNQPCIDLIESKLGILDLLDEECKMPKGTDGTWCQKLFDKCKASHH------FEKPRLSNTAFIIHHFADNVQYECGGFLEKNRDTVIEEQLNILKASQIDLVVELFAEKKAAPSGKSRGPQVTVKSAVSTL------KTQKTHKKTVGSQFRDSLTLLMETLNATTPQYVRCIKPNDQKLSFTFDPKRAIQQLRACGVLETIRISAAGYPSRWTYVEFFNRYRVLSRTKDIKRNDMKTTCLNILEKIIKDTDKYKFGKTKIFFRAGQVAYLEKLRSDKMRACCILIQKHVRGWLHRNRYQRMRWAAIQIQRYIRGFLARRLARFLRRTKAAICIQRYLRGYYEWKKYQHIRRSIISLQSYARGMWARQHYVELLHDAKATIIQKCVRGWLARLKYQKSLKAIVLLQSCVRRMYARRELKKLKIEARSVEHVKKLNQGLENKIISLQQKMDQLTKENNQMKSYEAELIKLKNLIDARGGEAEMKRMSSRIDQLEKEILTLRADLLNEQTEKEEILNEKEKSIIELQKVLTVWNKDTAELKEKLCLANETIKNQEKELEEILISKSESEKMLHDEFESERVNYQKILKDYARLEQRFENLQSENQVMKKQTHQRTPSNLSTISIESTGTEPARNEEMDNEDLGYGSTRSMRALEDQHKKLENVDWSIASQVEKEEKEAQLKSEKPTVCVTRDDV----DIGLVLKLQQRIKELQDRNKRLEDKLENKDDLSPSEKHEMRPFEALRIQDLEMENAKLKDNFNKIRSTIETGNKDKQIQLIVDQHSALEDELERRRDECLQLRTLLANKSLDSHAISKEMYGGNDELIN-EDGELYQLYHAQRQIIRQLEKELQGNKVNYSNEIDDLRKEMGRLREDNER------QQKLIGQLTGDSFAHLQMSPEAKTEAIMQHEITRLTGENLDLQEKADEYKETIKQLKKRLKIYAKKLKDGGTGQSQRSSLLSPYGS--DVGTELERRDSNENMPAVKHKEV-NYLGMFEYKKESEPYLIKSLIIDLKPSIAVNLLP-GLPAYILFMCIRHTDYINDDEKVRSLLTSTINGIKRVIKKKHEDFEIVVLWLTNICRLLHNLKQYSGDKTFQVDNTPKQNEQCLRNFDLSEYRQILSDIAVWIYQGIVKIMEETIQP--FVVAAILEHEAIAGLSGKKPLGMRGRSMSTTQ-ENTSPTSPAKSLDSLNKALDNFYDGFIKFGSDPE-IISQIFRQIFYFICAGALNNLLLRKDLCHWSKGMQMRYNCSHMEQWLRDHKLQECGAVEQLSPIIQASQLLQAR-KTDEDVDSICDMCDKLTLSQIIKMLNLYTPADVFEERVPVSFIRKIQAKLQ-ERGEANPQLLMDTKHA--FPVRFPFNPSNVQLEDIEIPESLNISFL 1848
BLAST of Dach-2 vs. TrEMBL
Match: A0A1V4JEV1 (Unconventional myosin-Va isoform D OS=Patagioenas fasciata monilis OX=372326 GN=MYO5A PE=3 SV=1) HSP 1 Score: 1117.84 bits (2890), Expect = 0.000e+0 Identity = 723/1902 (38.01%), Postives = 1087/1902 (57.15%), Query Frame = 2
Query: 62 MYSKGVKIWIPDEESVWIGATVLQFHKEKN-VIKIITDNGISKELNLSSK-KCAPFLRNPDILIGQKDLTYLSYLNEPEVLYNLQIRFCERREIYTYCGIVLVAINPYQELSIYGKEIINAYHSQNSVDLDPHIFAVAENAFRRMSSFGENQSIIVSGESGAGKTVSAKYTMRYFALVGGSKTKQSFNLTETQIERKVLLSNPILEAFGNAKTIRNDNSSRFGKYLEILFNPRNQVIGANMCTYLLEKSRVVFQNLGERNYHIFYQIVTHCQSEDELLMNTGLVNNVEMYDYLRYGESLEIDGVDDSHEFLITKNSFLQLGIDLNKFKTICEILAAILHLGNIRFRFHDATDSSIIENPELLKLIAGLLGCSIDQLKIWLCFRTISTFQETLHKPLSKAEAQYFRDAFVKTLYSNLFDWIVKQANKVLSTDVSINIKKKLKKTIVVNQEDKKKFIAVLDIYGFETFAENSFEQFCINFANEKLQLQFNLHVFKLEQEEYMNEGLEWTFIDYYNNQPCIDLIESRXXXXXXXXXXXXXXXXSDENWCCKIYSHHLNKSANFNKPKLSNMVFIIEHFAGPVEYKCAGFIEKNRDSVLEEQINLLKASDVQLIAELFRDSEIEIFDTNNXXXXXXXXXXXXXXXXXXQ--ENTRKMKKTVGSQFRNSLKSLMDALNKTNPHYVRCIKPNDLKLPFTFCPERAVQQLRACGVLETIRLSAAGFPSRWTYSDFYHRYYILMSNFNVKNHDFKAGSQKIVETLITVPDAFRFGNTKLFFRPGQVALLEKLRGHKIESSVTLIQSILRGSIERKKYLIIHKLTVQIQTYIRRKLAIEKATKLSQIRAVIIIQSFYRMYLARKLFVKMKCAVLAIEKWRRKIITTRLKQAYKKENCVIICQAIVRRFIQRRKFLKIQRGVILIQNHYRRRKAKETLKILKIEARSINHIKFVNKGLENKIIELTQKLDTKEKEMCXXXXXXXXXXXXXXXXXXXXXA---------ESAKIYQNTVQDLQTEIIQLKKELNREIVEKNKI--FADKELLEINYKKKINYLENLIEELKSSPSVI-----EPNIICNGDEAQQSICQDEHQKFI-----------NEQMDHQKLVREYEKLEMKYENLYKEFLFVKSSNQKPSINYDNQTSNDSETESTFSKDDADVESLSDKVDAKTTKEHXXXXXXXXXXLPNFISESISTAGDLAVVMQLQMNISSLSQENNRLKETVQQFEDELLKYEQCAEDSKGLVIHNEYDNELLSIIKDIKGMDEHGLKSRLIDEVANLKKKLKQS-NEDYQKLRLHIFDGSMSKLTGNLDHESINSEEEELKRA-FESQKEANRK---------MLKEIEGIKANNVDLKKALFQIRKDKEQLQVQLGKQHLMIRHGVEYL----QNLK---------------LTPKERLDKFVQNEISRILLENLKLQERNDQIISETIELKRGLKYFAFRLQKYEGSLVPNPNKEEDLLQLIQNVIYHSKMKTIGKRECYSEIGLIDLNMSELSIFIKSFIFDLSP-SICLQYEPYHLVPYIIFMVTRKFDFYKEEDQMTNFLSKLIVALKRTIRKRRNYIEYLVMLLSNVFCLVNLXXXXXXXXXXXXLNTAEDIQHYFVHYDLNEFIRLLKELCVTLFQMILKTIVDNLLPQSLCIDAILVHEAI--IDFLSKDGTKYKSNIETQPKNTSFNVLTKNLQSVLEILKNHKIPQLIINQIFVHIAYLINAYCLNTLLFRTDLCYFSKGLQIKYNLSSFETWIRYQKLIDSGALQCLRPMTEAVQLLQTLIDSDEDAKFVCDMCEYLNTRQVVKILNNFNPRDGYGCRLSSGLIAKIETQMKIKRGDEPSESKLETPTVIEIPIDIPFIHNGVSLCRTIIPKPLYLSCLT 5575
MY K ++WIPD E VW A +L+ +K + V+++ + G E L K K P LRNPDIL+G+ DLT LSYL+EP VL+NL++RF + + IYTYCGIVLVAINPY++L IYG++IINAY QN D+DPHIFAVAE A+++M+ NQSIIVSGESGAGKTVSAKY MRYFA V GS +E +E KVL SNPI+E+ GNAKT RNDNSSRFGKY+EI F+ R ++IGANM TYLLEKSRVVFQ ERNYHIFYQ+ C S T + N + Y + G S IDGVDD+ E L T+ + LGI + I ILA ILHLGN+ F D+ ++ E L + L+G +++ WLC R ++T ET KP+SK A RDA K +Y+NLF+WIV NK L V + FI VLDIYGFETF NSFEQFCIN+ANEKLQ QFN+HVFKLEQEEYM E + WT ID+Y+NQPCI+LIE+++G+LDLLDEECK+ KGSD+ W K+Y+ HLNK A F KP+LSN FII+HFA VEY+C GF+EKN+D+V EEQI +LK+S +L+ ELF+D E + T+ + S T + + + +++ KKTVG QFRNSL LM+ LN T PHYVRCIKPND K PFTF +RAVQQLRACGVLETIR+SAAGFPSRWTY +F+ RY +LM +V + D K + ++E LI D ++FG TK+FFR GQVA LEK+R K+ ++ IQ +RG + RKKY+ + K + IQ ++R A A L + RA I IQ F RMY+ RK + +M+ A +A++ R + Q +E+ +I Q VR ++ R ++ + + ++ +Q YRR AK LK LKIEARS+ K ++ GLENKI++L +K+D + KE + ++ + + ++ E AK N V LQ EI +L+KEL++ EK I +ADK YK + E L+ ELK +++ E N + D+A++ I + +K + +E++ +Q L+ E+ +LE +Y++L K+ + + S KP + T + +E+E TFS + + E L +++ + K+ D+++ ++LQ ++ L QE L++ + + E++ L+ + E+ + + E + E L K + +L +E+ L+K L ++ + + + + +LT + + EE + R+ SQKEA + +L++++ +K + ++ +A +++ L+ QL Q + +E L Q LK L P+ R++ +Q+EI+R+ ENL L E+ ++ +LK+ LK FA ++ + E + N + + + + I+ V K K G+++ + +K+ I +L P + + P L YI+FM R D+ ++ ++ + L+ I +K+ ++KR + E + LSN ++ +QYSG + F NT +H ++DL E+ ++L +L + ++Q +++ +++N+L Q + + +L HE I + + G + +++ + + + + L S ++ H + +I Q+ + Y+I A LN LL R D+C +SKG+QI+YN+S E W+R + L++SGA + L P+ +A QLLQ +DEDA+ +C MC L T Q+VK+LN + P + + R+ I I+ +++ R D P +L P+ PF + ++L IP L L ++
Sbjct: 98 MYVKYARVWIPDPEEVWKSAELLKDYKPGDKVLQLRLEEGKDLEYCLDPKTKELPPLRNPDILVGENDLTALSYLHEPAVLHNLKVRFIDSKLIYTYCGIVLVAINPYEQLPIYGEDIINAYSGQNMGDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYFATVSGSA-------SEANVEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRIIGANMRTYLLEKSRVVFQAEEERNYHIFYQL---CASAALPEFQTLRLGNANYFHYTKQGGSPVIDGVDDAKEMLNTRQACTLLGISDSYQMGIFRILAGILHLGNVEFASRDSDSCAVPPKHEPLTIFCDLMGVEYEEMAHWLCHRKLATATETYIKPISKLHAINARDALAKHIYANLFNWIVDHVNKALHATVK-----------------QHSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKEQIPWTLIDFYDNQPCINLIEAKMGVLDLLDEECKMPKGSDDTWAQKLYNTHLNKCALFEKPRLSNKAFIIKHFADKVEYQCEGFLEKNKDTVYEEQIKVLKSSKFKLLPELFQDEEKVLSPTSAAPSGRVPLSRTAVKAAKARPGQASKEHKKTVGHQFRNSLHLLMETLNATTPHYVRCIKPNDFKFPFTFDEKRAVQQLRACGVLETIRISAAGFPSRWTYQEFFSRYRVLMKQRDVLS-DRKQTCKNVLEKLILDKDKYQFGKTKIFFRAGQVAYLEKIRADKLRAACIRIQKTIRGWLMRKKYVRMRKAAIAIQRHVRGYQARCYAKFLRRTRAAITIQKFQRMYVVRKRYQRMRDATIALQALLRGYMARNKYQMMLREHKSVIIQKHVRGWLARLRYGRTLKAIVYLQCCYRRMMAKRELKKLKIEARSVERYKKLHIGLENKIMQLQRKIDEQNKEYKSLLEKMSSLEITYSTETEKLRSDVERLRMSEEEAKNATNRVLSLQDEIAKLRKELHQTQAEKKTIEEWADK------YKHET---EQLVSELKEQNTLLKTEKEELNRRIH-DQARE-ITETMEKKLVEETKQLELDLNDERLRYQNLLNEFSRLEERYDDL-KDEMNLMVSVPKPGHKRTDSTHSSNESEYTFSSEITEAEDLPVRMEEPSEKK---------------------APLDMSLFLKLQKRVTELEQEKQSLQDELDRKEEQALR-AKAKEEERPPIRGAELEYESL------KRQELESENKKLKNELNELQKALTETRSPEVTAPGAPAYRVLLDQLTSVSEELEVRKEEVLILRSQLVSQKEAIQPKNTMTDSTILLEDVQKMK-DKGEIAQAYIGLKETNRLLESQLQSQKKSHENELELLRGEIQGLKEENNRQQQLLAQNLQLPPEARIEASLQHEITRLTNENLDLMEQLEKQDKTVRKLKKQLKVFAKKIGELEVGQMENISPGQIIDEPIRPVNIPRKEKDFQ--------GMLEYKKEDEQKLVKNLILELKPRGVAVNLIP-GLPAYILFMCVRHADYLNDDQKVRSLLTSTINGIKKVLKKRGDDFETVSFWLSNTCRFLHCLKQYSGEEGFMKHNTPRQNEHCLTNFDLAEYRQVLSDLAIQIYQQLVR-VLENIL-QPMIVSGMLEHETIQGVSGVKPTGLRKRTSSIADEGTYTLDSIIRQLNSFHSVMCQHGMDPELIKQVVKQMFYIIGAVTLNNLLLRKDMCSWSKGMQIRYNVSQLEEWLRDKNLMNSGAKETLEPLIQAAQLLQVKKKTDEDAEAICSMCNALTTAQIVKVLNLYTPVNEFEERVLVSFIRTIQMRLR-DRKDSP---QLLMDAKHIFPVTFPFNPSSLALETIQIPASLGLGFIS 1915
BLAST of Dach-2 vs. Ensembl Cavefish
Match: myo5aa (myosin VAa [Source:ZFIN;Acc:ZDB-GENE-041027-2]) HSP 1 Score: 1088.95 bits (2815), Expect = 0.000e+0 Identity = 717/1892 (37.90%), Postives = 1069/1892 (56.50%), Query Frame = 2
Query: 83 IWIPDEESVWIGATVLQFHKEKN-VIKIITDNGISKELNLSSK-KCAPFLRNPDILIGQKDLTYLSYLNEPEVLYNLQIRFCERREIYTYCGIVLVAINPYQELSIYGKEIINAYHSQNSVDLDPHIFAVAENAFRRMSSFGENQSIIVSGESGAGKTVSAKYTMRYFALVGGSKTKQSFNLTETQIERKVLLSNPILEAFGNAKTIRNDNSSRFGKYLEILFNPRNQVIGANMCTYLLEKSRVVFQNLGERNYHIFYQIVTHCQSEDELLMNTGLVNNVEMYDYLRYGESLEIDGVDDSHEFLITKNSFLQLGIDLNKFKTICEILAAILHLGNIRFRFHDATDSSIIENPELLKLIAGLLGCSIDQLKIWLCFRTISTFQETLHKPLSKAEAQYFRDAFVKTLYSNLFDWIVKQANKVLSTDVSINIKKKLKKTIVVNQEDKKKFIAVLDIYGFETFAENSFEQFCINFANEKLQLQFNLHVFKLEQEEYMNEGLEWTFIDYYNNQPCIDLIESRXXXXXXXXXXXXXXXXSDENWCCKIYSHHLNKSANFNKPKLSNMVFIIEHFAGPVEYKCAGFIEKNRDSVLEEQINLLKASDVQLIAELFRDSEIEIFDTNNXXXXXXXXXXXXXXXXXXQ-ENTRKMKKTVGSQFRNSLKSLMDALNKTNPHYVRCIKPNDLKLPFTFCPERAVQQLRACGVLETIRLSAAGFPSRWTYSDFYHRYYILMSNFNVKNHDFKAGSQKIVETLITVPDAFRFGNTKLFFRPGQVALLEKLRGHKIESSVTLIQSILRGSIERKKYLIIHKLTVQIQTYIRRKLAIEKATKLSQIRAVIIIQSFYRMYLARKLFVKMKCAVLAIEKWRRKIITTRLKQAYKKENCVIICQAIVRRFIQRRKFLKIQRGVILIQNHYRRRKAKETLKILKIEARSINHIKFVNKGLENKIIELTQKLDTKEKE---------MCXXXXXXXXXXXXXXXXXXXXXAESAKIYQNTVQDLQTEIIQLKKELNREIVEKNKIFADKELLEINYKKKINYLENLIEELKSSPSVI--EPNIICNGDEAQQSICQDEHQKFINEQMD------------HQKLVREYEKLEMKYENLYKEFLFVKSSNQKPSINYDNQTSNDSETESTFSKDDADVESLSDKVDAKTTKEHXXXXXXXXXXLPNFISESISTAGDLAVVMQLQMNISSLSQE----NNRLKETVQQF---------------EDELLKYEQCAEDSKGLVIH-NEYDNELLSIIKDIKGMDEHGLKSRLIDEVANLKKKLKQSNEDYQKLRLHIFDGSMS-----KLTGNLDH-ESIN--SEEEELKRAFESQKEANRKMLKEIEGIKANNVDLKKALFQIRKDKEQLQVQLGKQHLMI----RHGVEYLQNLKLTPKERLDKFVQNEISRILLENLKLQERNDQIISETIELKRGLKYFAFRLQKYEGSLVPNPNKEEDLLQLIQNVIYHSKMKTIGKRECYSEIGLIDLNMSELSIFIKSFIFDLSP-SICLQYEPYHLVPYIIFMVTRKFDFYKEEDQMTNFLSKLIVALKRTIRKRRNYIEYLVMLLSNVFCLVNLXXXXXXXXXXXXLNTAEDIQHYFVHYDLNEFIRLLKELCVTLFQMILKTIVDNLLPQSLCIDAILVHEAI--IDFLSKDGTKYKSNIETQPKNTSFNVLTKNLQSVLEILKNHKIPQLIINQIFVHIAYLINAYCLNTLLFRTDLCYFSKGLQIKYNLSSFETWIRYQKLIDSGALQCLRPMTEAVQLLQTLIDSDEDAKFVCDMCEYLNTRQVVKILNNFNPRDGYGCRLSSGLIAKIETQMKIKRGDEPSESKLETPTVIEIPIDIPFIHNGVSLCRTIIPKPLYLSCLT 5575
+WIPD E VW A + + +K+ + ++ + ++G E L K K P LRNPDIL+G+ DLT LSYL+EP VL+NL++RF + + IYTYCGIVLVAINPY+ L IYG +IINAY QN D+DPHIFAVAE A+++M+ NQSIIVSGESGAGKTVSAKY MRYFA V GS + E +E KVL SNPI+EA GNAKT RNDNSSRFGKY+EI F+ + +IGANM TYLLEKSRVVFQ ERNYHIFYQ+ + + G N+ + Y + G + IDGVDD+ E T+N+F+ LGI+ + + ++LAAILHLGN+ + DA S I N L + L+G + + WLC R + T ET KP+ K +A RDA K +Y+ LF+WIV NK L + V + FI VLDIYGFETF NSFEQFCIN+ANEKLQ QFN+HVFKLEQEEYM E + WT ID+Y+NQPCI+LIE+++G+LDLLDEECK+ KGSD++W K+Y+ HL F KP++SN FII+HFA VEY+C GF+EKN+D+V EEQI++LKAS L+ ELF+D E T + K +++++ KKTVG QFRNSL+ LM+ LN T PHYVRCIKPND K FTF P+RAVQQLRACGVLETIR+SAAGFPSRWTY +F+ RY +LM +V D K + ++E L+ PD ++FG TK+FFR GQVA LEKLR K+ ++ IQ +R + RKK+L + + + IQ ++R A AT L + RA IIIQ + RMY+AR ++ + + A LA++ R + +L + ++ VII Q +VR ++ R+ + + ++ +Q RR +AK LK LKIEARS+ H K +N G+ENKI++L +K+D + KE + + E+ L+ E AK N V LQ E+ +L+ EL EK I E Y+ + +E +I ELK S++ E N + + Q ++ Q+ + E+ +Q L+ E+ +LE KY++L KE + + + KP + T + +E+E T++ + A+ E S ++ P+ D+A+ ++LQ ++ L QE N L +QF E E LK ++ ++K L + N+ L+ L+D++ + ++L+ E+ LR + + +T L H E ++ ++ +E+ +A+ K+ NR + +++ Q R + +L+V G+ + R QNL+L P+ R++ +Q+EI+R+ ENL L E+ ++ +LK+ LK FA ++ EG + N + + + I+ V +I +RE + G+++ + +K+ I +L P + + P L YI+FM R D+ ++ ++ L+ I ++K+ ++KR + E + L+N ++ +QYSG +QF NT + +H ++DL E+ ++L +L + ++Q ++K + +N+L Q + + +L HE I + + G + +++ + + + + L S I+ H +I Q+ Y+I A LN LL R D+C +SKG+QI+YN+S E W+R + L+ GA++ L+P+ +A QLLQ +DEDA+ +C MC L T Q+VK+LN + P + + R+S I I+T+++ D +L T I P+ PF + ++L IP L L+ LT
Sbjct: 20 VWIPDPEEVWRSAELTKDYKQGDALLHLQLEDGTDLEHKLDPKTKNLPHLRNPDILVGENDLTALSYLHEPAVLHNLKVRFIDSKLIYTYCGIVLVAINPYETLPIYGTDIINAYSGQNMGDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYFATVSGSAS-------EANVEEKVLASNPIMEAIGNAKTTRNDNSSRFGKYIEIGFDKKYHIIGANMRTYLLEKSRVVFQADEERNYHIFYQLCASAHLPEFKALKLGGAND---FHYTKQGRNPVIDGVDDAKEMSTTRNAFILLGINESYQMGLFQVLAAILHLGNVEVKDRDADSSIIPPNNRHLTVFCELMGVTYQDMSHWLCHRKLKTATETYIKPIPKLQAINARDALAKHIYAKLFNWIVDHVNKALHSTVK-----------------QHSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKEQIPWTLIDFYDNQPCINLIEAKMGILDLLDEECKMPKGSDDSWAQKLYNTHLKTCTLFEKPRMSNKAFIIQHFADKVEYQCDGFLEKNKDTVNEEQIHVLKASKFDLLVELFQDEEKATSPTGAPPTTGGRTRLSVKPDKGKPGKSSKEHKKTVGLQFRNSLQLLMETLNATTPHYVRCIKPNDYKHAFTFDPKRAVQQLRACGVLETIRISAAGFPSRWTYQEFFSRYRVLMKQKDVLA-DKKMTCKNVLEKLVQDPDKYQFGKTKIFFRAGQVAYLEKLRADKLRAACIRIQKTIRCWLARKKFLRMKRAAITIQRHVRGYQARCLATFLRRTRAAIIIQKYQRMYVARTMYRRKQAAALAMQCILRAYMARQLYKLLREHKAVII-QKMVRGWLARQWYKRSLDALVYLQCCVRRMRAKRELKKLKIEARSVEHYKKLNIGMENKIMQLQRKVDEQNKENRTLTERLNGLEVAHTAESERLRRELSRLRCAEEDAKNSNNRVITLQEELERLRAELQSTQKEKKAI----EDWAQTYQ---DEMEKMISELKDQNSLLKNEKNDLNRIIQEQGQQWTEKMQRALKEETTQLESDLNEERSRYQNLLTEHLRLEEKYDDL-KEEISLSVNVPKPGHRRTDSTHSSNESEYTYNSEFAESEEGSRGME------------------PSL---------DMALFLKLQKRVTELEQEKQGLQNELDRKDEQFQRDHEEHKKARSAELEYESLKRQELESENKKLKHNLNDMRQSLMGNTGAASAAPGSPAYKVLLDQLNSSNEELEVRKEEVLILRSQLVSQKEAMQHKETMTEPLHHVEDVHKLTDAKEISQAYMGLKDTNRLLESQLQS-------------QRRSHESELEVLRGELQSVKEENNRQQQLLAQNLQLPPEARIEASLQHEITRLTNENLDLMEQLEKQDKTVRKLKKQLKVFAKKINDLEGGQIENVSPGQMADEPIRPV-------SIPRREKDFQ-GMLEYKKEDELKLVKNLILELKPRGVAVNLIP-GLPAYILFMCLRHADYINDDQKVRALLTSTINSIKKILKKRGDDFETVSFWLANTCRFLHCLKQYSGDEQFMKYNTPKQNEHCLSNFDLAEYRQVLSDLAIQIYQQLIKCM-ENIL-QPMIVSGMLEHETIQGVSGVKPTGLRKRTSSIADEGTYTLDSIIRQLNSFHSIMCQHGTDPELIKQVVKQQFYIIGAVTLNNLLLRKDMCSWSKGMQIRYNVSQLEEWLRDKNLVVCGAMETLQPLIQAAQLLQVKKKTDEDAEAICSMCNALTTSQIVKVLNLYTPVNAFEERVSVTFIRTIQTRLR----DRKESPQLLLDTKIIYPVTFPFNPSPLALETIQIPGSLNLAFLT 1819
BLAST of Dach-2 vs. Ensembl Cavefish
Match: myo5b (myosin VB [Source:ZFIN;Acc:ZDB-GENE-031219-7]) HSP 1 Score: 988.793 bits (2555), Expect = 0.000e+0 Identity = 675/1805 (37.40%), Postives = 999/1805 (55.35%), Query Frame = 2
Query: 338 YTYCGIVLVAINPYQELSIYGKEIINAYHSQNSVDLDPHIFAVAENAFRRMSSFGENQSIIVSGESGAGKTVSAKYTMRYFALVGGSKTKQSFNLTETQIERKVLLSNPILEAFGNAKTIRNDNSSRFGKYLEILFNPRNQVIGANMCTYLLEKSRVVFQNLGERNYHIFYQI-VTHCQSEDELLMNTGLVNNVEMYDYLRYGESLEIDGVDDSHEFLITKNSFLQLGIDLNKFKTICEILAAILHLGNIRF-RFHDATDSSIIENPELLKLIAGLLGCSIDQLKIWLCFRTISTFQETLHKPLSKAEAQYFRDAFVKTLYSNLFDWIVKQANKVLSTDVSINIKKKLKKTIVVNQEDKKKFIAVLDIYGFETFAENSFEQFCINFANEKLQLQFNLHVFKLEQEEYMNEGLEWTFIDYYNNQPCIDLIESRXXXXXXXXXXXXXXXXSDENWCCKIYSHHLNKSANFNKPKLSNMVFIIEHFAGPVEYKCAGFIEKNRDSVLEEQINLLKASDVQLIAELFRDSEIEIFDTNNXXXXXXXXXXXXXXXXXXQENTRKMKKTVGSQFRNSLKSLMDALNKTNPHYVRCIKPNDLKLPFTFCPERAVQQLRACGVLETIRLSAAGFPSRWTYSDFYHRYYILMSNFNVKNHDFKAGSQKIVETLITVPDAFRFGNTKLFFRPGQVALLEKLRGHKIESSVTLIQSILRGSIERKKYLIIHKLTVQIQTYIRRKLA-----------IEKATKLSQIRAVIIIQSFYRMYLARKLFVKMKCAVLAIEKWRRKIITTRLKQAYKKENCVIICQAIVRRFIQRRKFLKIQRGVILIQNHYRRRKAKETLKILKIEARSINHIKFVNKGLENKIIELTQKLDTKEKEMCXXXXXXXXXXXXXXXXXXXXXAESAKIYQNTVQDLQTEIIQLKKELNREIVEKNKIFADKELLEINYKKKINYLENL--IEELKSSPSVIEP------NIICNGDEAQQSICQDE---HQKFINEQMDHQKLVREYEKLEMKYENLYKEFLFVKSSNQKPSINYDNQTSNDSET--ESTFSKDDADVESLSDKVDAKTTKEHXXXXXXXXXXLPNFISESISTAGDLAVVMQLQMNISSLSQENNRLKETVQQFEDELLKYEQCAEDSK-----GLVIHNEYDNELLSIIKDIKGMDEHGLKSRLIDEVAN-------------LKKKLKQSNE--DYQK---LRLHIFDGSMSKLT-GNLDHESIN------SEEEELKRAFESQKEANRKMLKEIEGIKANNVDLKKALFQIRKDKEQLQVQLGKQHLMIRHGVEYLQNLKLTPKERLDKF-VQNEISRILLENLKLQERNDQIISETIELKRGLKYFAFRLQKYEGSLVPNPNKEEDLLQLIQNVIYHSKMKTIGKRECYSEIGLIDLNMSELSIFIKSFIFDLSPSICLQYEPYHLVPYIIFMVTRKFDFYKEEDQMTNFLSKLIVALKRTIRKRRNYIEYLVMLLSNVFCLVNLXXXXXXXXXXXXLNTAEDIQHYFVHYDLNEFIRLLKELCVTLFQMILKTIVDNLLPQSLCIDAILVHEAIIDFLSKDGTKYKSNIETQ---PKNTSFNVLTKNLQSVLEILKNHKIPQLIINQIFVHIAYLINAYCLNTLLFRTDLCYFSKGLQIKYNLSSFETWIRYQKLIDSGALQCLRPMTEAVQLLQTLIDSDEDAKFVCDMCEYLNTRQVVKILNNFNPRDGYGCRLSSGLIAKIETQMKIKRGDEPSESKLETPTVIEIPIDIPFIHNGVSLCRTIIPKPLYLSCL 5572
+ + GIVLVAINPY++L IYG+E+INAY QN D++PHIFAVAE A+++M+ +NQSIIVSGESGAGKTVSAKY MRYFA VGGS +T +E KVL S+PI+EA GNAKT RNDNSSRFGKY++I F+ R +IGANM TYLLEKSRVVFQ ERNYHIFYQ+ + C E + L T + E + Y +GE++ I+GV+D+ + T+ + LG+ +I +I+A+ILHLGN+ D I + L LLG ++Q++ WLC R + T ET K +S A+A RDA K +Y++LFDWIV+ NK L T + FI VLDIYGFETF NSFEQFCIN+ANEKLQ QFN HVFKLEQEEYM E + WT ID+Y+NQPCIDLIE++LG+LDLLDEECK+ KG+D+NW K+YS HL KS +F KP++SN FI+ HFA VEY+C GF+EKNRD+V EEQIN+LKAS QL+A+LF++ + S + + + + + R+ +KTVG QFRNSL LM+ LN T PHYVRCIKPND K F F RAVQQLRACGVLETIR+SAAG+PSRWTY DFY RY +LM+ ++ D K + ++E+LI PD F+FG TK+FFR GQVA LEKLR K + IQ +RG ++R++YL I K + +Q Y R LA E A L +A +I Q YRM R+ ++ ++ AV+ I+ + R + T RL Q + + II Q VR ++ R+KFL+ + I+IQ YRR AK LK LKIEARS+ IK +N G+ENKI++L +K+D + KE QL + Q E + + Q T++ +++EL + + A ++ LE Y + LE + +EEL+ S+++ I + S Q E + E++ +Q L++E +LE + +NL +E F + PS NQ+S SE+ S D ++ + + ++D + + A DL+V M+LQ + L QE RL+ +++ E EL +++ S+ L ++ EL S K +K D + L+ L+D + L +LK +NE D +K L L S SK T N +H +++ +E+ EL A++ K+ R + +++ + D +AL Q+++ K+ L + E L + P E L +F VQ EI+R+ ENL L+E +++ +LK+ L+ + ++Q+ E S +L + V K K G+++ + ++ I++ + D+ P + P L YI+FM R D+ ++ ++ + L+ I A+K+ ++K + E L+N L++ +QYSG + F NT + +H ++DL E+ ++L +L + ++Q ++K I + +L Q + + A+L ++ S+++ + P + L + L I+ H + I Q+ + Y INA LN LL R D+C +S G+Q++YN+S E W+R + L SG L + P+ +A QLLQ + +DA+ +C +C L T+Q+VKILN + P + + R++ I I+ +++ D +L T P+ P+ + +SL +P L L L
Sbjct: 11 FCFTGIVLVAINPYEQLQIYGEEVINAYSGQNMGDMNPHIFAVAEEAYKQMARDEKNQSIIVSGESGAGKTVSAKYAMRYFATVGGSA-------NDTNVEEKVLASSPIMEAIGNAKTTRNDNSSRFGKYIQIGFDRRFHIIGANMRTYLLEKSRVVFQAEDERNYHIFYQLCASACLPEFKDLALT----SAEDFTYTSFGENIFIEGVNDAEDLEKTREALSLLGVKEIHQMSIFKIIASILHLGNVEIVSERDGESCHINRDDSHLHHFCQLLGVELEQMEHWLCHRKLVTTSETYVKNMSCAQATNARDALAKHIYAHLFDWIVEHVNKALHTS-----------------SKQHSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNSHVFKLEQEEYMKEQIPWTLIDFYDNQPCIDLIEAKLGILDLLDEECKVPKGTDQNWTQKLYSQHL-KSDHFEKPRMSNTSFIVVHFADKVEYQCDGFLEKNRDTVYEEQINILKASKFQLVADLFQEGK---EGPAPPPSGKSSRINVRPAKPAIKGHNREHRKTVGHQFRNSLHLLMETLNATTPHYVRCIKPNDSKEAFVFDSRRAVQQLRACGVLETIRISAAGYPSRWTYLDFYSRYRVLMTKKDMTVGDKKQVCRNLLESLIKDPDKFQFGKTKIFFRAGQVAYLEKLRADKFRFACIKIQKTVRGWLQRRRYLKIRKSAIMLQRYGRGYLAPYFAWIYCIYLTEHAEYLRLTKAALICQKQYRMVRVRRAYLTIRQAVITIQAFTRGMFTRRLYQEFLLHHKAIIIQRTVRGWLDRKKFLRARNAAIVIQCAYRRVLAKRQLKQLKIEARSVKRIKELNIGMENKIVQLQRKMDDQSKEYKNQNEQLSVTNTALGTEVNKLQKELETL--RSRQGDNTQLTSMQEELEKLRAALQESHAQRKRLEEEYSSEKLGLEQVRRVEELEKENSMLKTEKEEMNQKIRRSTSQEGSASQKEARLQAELDEERLRYQNLLKEISRLEQRCDNLQEE--FAPGHRRNPS----NQSSIGSESPFPSIAMSDVSETDGVIQQIDDMGPE---------------------NAAMDLSVFMKLQKRVRDLEQERKRLQTNLEKME-ELSQHKVSNSTSEVDGNTDLAYNSLKRQELESENKKLKN-DLNELRKALVDRASESCSSNELQDSYNLLLSQLKAANEELDVRKEEVLMLKTQIVSSSKATPDNTNHIALSEDWGYLNEDGELGLAYQGLKQVARLLETQLQSQSRKHQDELEAL--------HTQIEVLKEDLEKKQ--ETLNHFNTLPPEALVEFSVQQEITRLTNENLDLKEVMEKLEKNERKLKKQLRIYIKKVQELEVSQAVAAQSSRARPELTRQVTVQRKDKDFE--------GMLEYIKEDEALLIRTLVTDMKPHVVSATVPC-LPAYILFMCIRHADYINDDQKVHSMLTSTINAVKKVLKKNNDDFEMTSFWLANTSRLLHCLKQYSGDEAFMTQNTPKQNEHCLKNFDLAEYRQVLSDLSIQIYQQLIK-IAEAIL-QPMIVSAMLESGSLTGVKPMGYRNRSSSMDCETGGPGGYTLEALIRQLGQFNTIMGEHGLDPEIGQQVIRQLFYSINAVTLNNLLLRKDVCSWSTGMQLRYNISQMEEWLRGRNLHQSGVLATIEPLIQAAQLLQVKKKTSQDAEAICTLCSALTTQQIVKILNLYTPLNEFEERVTVSFIRDIQNRLQ----DRIENKQLLVDTKHTFPVLFPYTPSALSLETIHMPASLNLDFL 1727
BLAST of Dach-2 vs. Ensembl Cavefish
Match: myo5ab (myosin VAb [Source:ZFIN;Acc:ZDB-GENE-050411-72]) HSP 1 Score: 968.763 bits (2503), Expect = 0.000e+0 Identity = 675/1899 (35.55%), Postives = 1007/1899 (53.03%), Query Frame = 2
Query: 62 MYSKGVKIWIPDEESVWIGATVLQ-FHKEKNVIKIITDNGISKELNLSSKKCA-PFLRNPDILIGQKDLTYLSYLNEPEVLYNLQIRFCERREIYTYCGIVLVAINPYQELSIYGKEIINAYHSQNSVDLDPHIFAVAENAFRRMSSFGE-NQSIIVSGESGAGKTVSAKYTMRYFALVGGSKTKQSFNLTETQIERKVLLSNPILEAFGNAKTIRNDNSSRFGKYLEILFNPRNQVIGANMCTYLLEKSRVVFQNLGERNYHIFYQIVTHCQSEDELLMNTGLVNNVEMYDYLRYGESLEIDGVDDSHEFLITKNSFLQLGIDLNKFKTICEILAAILHLGNIRFRFHDATDSSIIENPELLKLIAGLLGCSIDQLKIWLCFRTISTFQETLHKPLSKAEAQYFRDAFVKTLYSNLFDWIVKQANKVLSTDVSINIKKKLKKTIVVNQEDKKKFIAVLDIYGFETFAENSFEQFCINFANEKLQLQFNLHVFKLEQEEYMNEGLEWTFIDYYNNQPCIDLIESRXXXXXXXXXXXXXXXXSDENWCCKIYSHHLNKSANFNKPKLSNMVFIIEHFAGPVEYKCAGFIEKNRDSVLEEQINLLKASDVQLIAELFRDSEIEIFDTNNXXXXXXXXXXXXXXXXXXQENTRKMKKTVGSQFRNSLKSLMDALNKTNPHYVRCIKPNDLKLPFTFCPERAVQQLRACGVLETIRLSAAGFPSRWTYSDFYHRYYILMSNFNVKNHDFKAGSQKIVETLITVPDAFRFGNTKLFFRPGQVALLEKLRGHKIESSVTLIQSILRGSIERKKYLIIHKLTVQIQTYIRRKLAIEKATKLSQIRAVIIIQSFYRMYLARKLFVKMKCAVLAIEKWRRKIITTRLKQAYKKENCVIICQAIVRRFIQRRKFLKIQRGVILIQNHYRRRKAKETLKILKIEARSINHIKFVNKGLENKIIELTQKLD--TKEKEMCXXXXXXXXXXXXXXXXXXXXXAESAKIYQNTVQDLQTEIIQLKKELNR--EIVEKNKIFADKELLEINYKKKINYLENLIEELKSSPSVIEPNIICNGDEAQQSICQDEHQKFIN-----EQMDHQKLVREYEKLEMKYENLYKEFLFVKSSNQKPSINYDNQTSNDSETESTFSKDDADVESLSDKVDAKTTKEHXXXXXXXXXXLPNFISESISTAG-----DLAVVMQLQMNISSLSQENNRLKETVQQFEDELLKY-----EQCAEDSKGLVIHNEYD------------------NELLSIIKDIKGMDEHGLKSR----LIDEVANLKKKLKQSNEDYQKLRLHIF--------------DGSMSKLTGNLDHESINSEEEELKRAFESQKEANRKMLKEIEGIKANNVDLKKALFQIRKDKEQLQVQLGKQHLMIRHGVEYLQNLKLTPKERLDKFVQNEISRILLENLKLQERNDQIISETIELKRGLKYFAFRLQKYEGSLVPNPNKEEDLLQLIQNVIYHSKMKTIGKRECYSEIGLIDLNMSELSIFIKSFIFDLSP-SICLQYEPYHLVPYIIFMVTRKFDFYKEEDQMTNFLSKLIVALKRTIRKRRNYIEYLVMLLSNVFCLVNLXXXXXXXXXXXXLNTAEDIQHYFVHYDLNEFIRLLKELCVTLFQMILKTIVDNLLPQSLCIDAILVHEAIIDFLSKDGTKYKSNIETQPKNTSFNV--LTKNLQSVLEILKNHKIPQLIINQIFVHIAYLINAYCLNTLLFRTDLCYFSKGLQIKYNLSSFETWIRYQKLIDSGALQCLRPMTEAVQLLQTLIDSDEDAKFVCDMCEYLNTRQVVKILNNFNPRDGYGCRLSSGLIAKIETQMKIKRGDEPSESKLETPTVIEIPIDIPFIHNGVSLCRTIIPKPLYLSCLT 5575
+YSK ++WIPD VW A + + + +++ ++G E L K P LRNPDIL+G+ DLT LSYL+EP VL+NL +RF + + IYTYCGI+LVAINPY+ L IYG +IINAY QN D+DPHIFAVAE A+++M+ F E NQSIIVSGESGAGKTVSAKYTMRYFA V GS T ET +E KVL S+PI+EA GNAKT RNDNSSRFGKY+EI F+ +IGANM TYLLEKSRVVFQ ERNYHIFYQ+ + + G ++ + G + IDGVDD E T+ +F LGI + + +ILAAILHLGN+ + +SS+ L + LL S + + WLC + + T ET +KPL+K EA RDA K +Y+ LF WIV Q NK L ++ + FI VLDIYGFETF NSFEQFCIN+ANEKLQ QFN+HVFKLEQEEY+ E + WT ID+Y+NQPCI+LIE+++G+LDLLDEEC + E W C IYS + + H VEY+C GF+EKN+D+V EEQIN+LK+S L+ ELF++ + T + + ++ R+ KK+VG QFRNSL LMD LN T PHYVRCIKPND K PF P RA QQLRACGVLETIR+SAAGFPSRWTY +F+ RY +LM +V + D K Q +++ LI PD ++FG TK+FFR GQVA LEKLR K+ ++ IQ +R + RKKYL + T+ IQ Y+R + A L + +A ++IQ + RM AR+L+ + + A + +++ R + + E V++ Q VR ++ R ++ + + V+ +Q RR A+ LK LKIEARS+ H K +N G+ENKI++L +K+D KE + L + +I+ + L Q E+ + + + L ++ L++EL E +EKN+ K + E+N K + LKS + I ++ QQ EH + + E+ +Q L+ E+ KLE ++ +L K +N T+S +S ++++ S+ F +S G D+A++++LQ ++ L QE L+ ED L ++ E+C G +Y+ NEL + + KG S L+++++++ ++L+ E+ LR + D + + LD +N E+ EL +E KE NR + +++ + + +AL + + + L+ + +Q ++ H L+L R+ +Q EISR+ N+ L E+ D+ +LK+ LK + + ++ + V P E +++ + + K +R C G+++ + S +K I +L P + + P L YI+FM R DF + ++ L+ I +K ++K+ + E + L+N L++ +QYSG + ++ NTA+ + +++DL E+ ++L +L + ++Q ++K + +N+L Q + + +L + I L T + + P+++SF++ L K L S L H +I Q+ Y I A LN+LL R D+C ++KGLQI+YN+S E W+ + G + L P+ +A +LLQ ++EDA+ + MC L V + + + C SS Q +K E + +++ V PI PF + V+L IP L LS LT
Sbjct: 7 LYSKYARVWIPDPVDVWKSAELTKDYTPGDTALQLELEDGTELEYKLDPKNSTLPPLRNPDILVGENDLTALSYLHEPAVLHNLSVRFIDSKLIYTYCGIILVAINPYESLPIYGADIINAYSGQNMGDMDPHIFAVAEEAYKQMARFDERNQSIIVSGESGAGKTVSAKYTMRYFATVSGSST-------ETSVEEKVLASSPIMEAIGNAKTTRNDNSSRFGKYIEIGFDKNYYIIGANMRTYLLEKSRVVFQANEERNYHIFYQLCASAHLPEFKALQLGRADD---FHCTNQGGNPVIDGVDDVQEMQATQRAFSLLGISEKQQMDLFQILAAILHLGNVEVMGKGSGNSSVSAQNHHLTVFCELLMVSQEDIAHWLCHKKLKTATETFNKPLAKTEAVDGRDALAKHIYARLFTWIVSQINKAL-----------------LSSSKQHSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNMHVFKLEQEEYLKEQIPWTLIDFYDNQPCINLIEAKMGILDLLDEECMFVVYYFECWHCSIYSGYKKST----------------HPCSNVEYQCEGFLEKNKDTVNEEQINVLKSSKFALLLELFQEEDKAPGPT--------ATAVPSRFKVGRSQSLREHKKSVGLQFRNSLNLLMDTLNATTPHYVRCIKPNDHKSPFMMDPRRAAQQLRACGVLETIRISAAGFPSRWTYQEFFIRYRVLMKQKDVLS-DGKLTCQNVLQQLIQDPDKYKFGKTKIFFRAGQVAYLEKLRADKLRAACVQIQKTIRCYVARKKYLRLRWSTITIQRYVRGQQARALCKSLRRTKAAVVIQKYQRMCAARRLYQRKQLAAVLLQRLLRGYAARLQYKQLRYEQKVVVVQRWVRGWLARVQYRRTMQAVVYLQCCVRRMLARRELKKLKIEARSVEHYKKLNVGMENKIMQLQRKVDEQNKENKELLERISVIESSSVAELKKLRPQIEALRGVEEDARRLNDKVSTLEEELQVTCEELEKNR----KMVEELNEKNSL---------LKSEKDELNTMI---KEQGQQITAHQEHVELLQTELYEERSRYQNLLTEHLKLEEQHADL------------KSEMNEHVSKLGRLGTDSAYSSNESEYTRCSE-----------------------FTGSEVSLQGQEGGVDVALLLKLQRRVAELEQEKLNLQSEWDSREDLLQQHHAKELEECRRTVGG---ERDYEAQKRQELESDNKRLKKDLNELRASLSVKKGSGRASPGSSAYNVLLEQLSSVTEELEVRKEEVLLLRTQLVSLEAFKYKEAASEGDAGDTSRSPTLDLHELN-EDGELWIVYEGLKETNRLLESQLQSEREHQAQELQAL---KAELQTLKEERDQQQQLLSH------TLQLPKDGRVHTALQLEISRLTRHNVDLLEQMDKQDKTIRKLKKQLKIYMKKAEETDYVHVDEPIPENRVIEAMPEISILRK-----ERHCR---GMLEYGNDDESKLVKILITELKPRGVAVSMIPC-LPAYILFMCLRHADFTNNDQRVCTLLNCSINCIKSVLKKKGDDFETVSFWLANTCRLLHCLKQYSGEEDYTKHNTAQQNEQCLLNFDLTEYRQVLSDLIIQIYQQLIKCM-ENIL-QPMIVAGMLEQDTIPVLLGPKPTGLRKRTSSFPQDSSFSLESLLKQLSSFHSTLLQHGNDPDLIRQVVKQQFYFIGAVTLNSLLLRKDMCSWNKGLQIRYNVSQLEEWLMDAGVQGGGMREMLEPLIQATKLLQVNKKTEEDAEAIATMCTALTIDISVFVYLSV-----HVCARSSLNFLLCSPQALLKNRQESPQLLMDSKIV--FPITFPFNPSPVALESIQIPASLNLSFLT 1771
BLAST of Dach-2 vs. Ensembl Cavefish
Match: myo5c (myosin VC [Source:ZFIN;Acc:ZDB-GENE-131127-196]) HSP 1 Score: 779.63 bits (2012), Expect = 0.000e+0 Identity = 429/922 (46.53%), Postives = 595/922 (64.53%), Query Frame = 2
Query: 47 MALYEMYSKGVKIWIPDEESVWIGATVLQ-FHKEKNVIKIITDNGISKELNLSSKKCAPFLRNPDILIGQKDLTYLSYLNEPEVLYNLQIRFCERREIYTYCGIVLVAINPYQELSIYGKEIINAYHSQNSVDLDPHIFAVAENAFRRMSSFGENQSIIVSGESGAGKTVSAKYTMRYFALVGGSKTKQSFNLTETQIERKVLLSNPILEAFGNAKTIRNDNSSRFGKYLEILFNPRNQVIGANMCTYLLEKSRVVFQNLGERNYHIFYQIVTHCQSEDELLMNTGLVNNVEMYDYLRYGESLEIDGVDDSHEFLITKNSFLQLGIDLNKFKTICEILAAILHLGNIRFRFHDATDSSIIENPELLKLIAGLLGCSIDQLKIWLCFRTISTFQETLHKPLSKAEAQYFRDAFVKTLYSNLFDWIVKQANKVLSTDVSINIKKKLKKTIVVNQEDKKKFIAVLDIYGFETFAENSFEQFCINFANEKLQLQFNLHVFKLEQEEYMNEGLEWTFIDYYNNQPCIDLIESRXXXXXXXXXXXXXXXXSDENWCCKIYSHHLNKSANFNKPKLSNMVFIIEHFAGPVEYKCAGFIEKNRDSVLEEQINLLKASDVQLIAELFRDSEIEIFDTNNXXXXXXXXXXXXXXXXXXQENTRKMKKTVGSQFRNSLKSLMDALNKTNPHYVRCIKPNDLKLPFTFCPERAVQQLRACGVLETIRLSAAGFPSRWTYSDFYHRYYILMSNFNVKNHDFKAGSQKIVETLITVPDAFRFGNTKLFFRPGQVALLEKLRGHKIESSVTLIQSILRGSIERKKYLIIHKLTVQIQTYIRRKLAIEKATKLSQIRAVIIIQSFYRMYLARKLFVKMKCAVLAIEKWRRKIITTRLKQAYKKENCVIICQAIVRRFIQRRKFLKIQRGVILIQNHYR 2809
MAL E+Y+K ++WIPD E VW A +L+ F + + ++G + + P LRNPDIL+G+ DLT LSYL+EP VL+NL++RF + R IYTYCGI+LVA+NPY++L IYG +I+AY QN DLDPHIFAVAE A+++M+ +NQSIIVSGESGAGKTVSA+Y MRYFA+V S + + ++E KVL SNPI EA GNAKT RNDNSSRFGKY EI F+ R Q+IGANM TYLLEKSRVVFQ+ ERNYH+FYQ+ C D+ + + + + ++Y G EI GVDD + T+ +F LG+ + + ++LA ILHLGN+ + + SSI + L + LLG +++ WLC R I ET+ KP K A RDA K LY+ LFD ++ + N+ L + FI VLDIYGFETF NSFEQFCIN+ANEKLQ QFNLHVFKLEQEEYM E + WT ID+Y+NQP IDLIE+++G+LDLLDEEC +G+D+NW K+Y++ L +F KP+LSN F+I+HFA V+Y+C GF+EKNRD++ EE +++++AS L+ + F + E NN+ KV +K++ + + ++++ TVG +FR+SL LM+ LN T PHYVRCIKPN+ KLPF + +R VQQLRACGVLET+ +SA +PSRWTY +FY RY ILMS ++ D K + +++ LI + ++FG TK+FFR GQVA LEKLR ++ ++ +IQ LRG +R++YL + + + IQ YIR K A L Q A ++IQ R YL R+L+ ++ A + I+ + R + + + +E+ ++ Q R ++ RR+F ++R V+ +Q YR
Sbjct: 1 MALQELYTKYNRVWIPDSEQVWKSAEILKDFSPGDPTLHLQLEDGTVLQYPVEGPGQLPHLRNPDILVGENDLTALSYLHEPAVLHNLRVRFVDSRIIYTYCGIILVAVNPYKQLPIYGDGVIHAYSGQNMGDLDPHIFAVAEEAYKQMARNNQNQSIIVSGESGAGKTVSARYAMRYFAMVSKSSSNK-------RVEDKVLASNPITEAIGNAKTTRNDNSSRFGKYTEISFDRRYQIIGANMRTYLLEKSRVVFQSENERNYHVFYQM---CACADQPEFKSLRLLSADKFNYTCMGGDTEIQGVDDCADMAETRRTFSLLGLKEDFQSDVFKMLAGILHLGNVVIKAVGSDQSSISSSDSHLVVFCDLLGVRGEEMSRWLCHRRIVLASETVVKPQPKERAINARDALAKHLYAYLFDCVILRINQALRVPGK-----------------QHSFIGVLDIYGFETFDVNSFEQFCINYANEKLQQQFNLHVFKLEQEEYMKEDIPWTLIDFYDNQPVIDLIEAKMGILDLLDEECLFPQGTDKNWLQKLYNY-LGSKPHFEKPRLSNEAFVIQHFADKVQYQCRGFLEKNRDTLYEELVDVMRASKFPLLTDFFTEEE------NNAVTKVKVKAARPGV----KPANKQLRSTVGDKFRSSLYLLMETLNATTPHYVRCIKPNEEKLPFEYDSKRVVQQLRACGVLETVHISAQSYPSRWTYIEFYSRYSILMSQAELRAGDKKQICRTVLQRLIHDSNQYKFGRTKIFFRAGQVAYLEKLRLDRLRTACIIIQKHLRGWSQRRRYLRLRQAAIIIQEYIRGKRRTVTAAALKQGWAAVVIQRHCRGYLVRRLYQLLRVAAITIQAYVRGWMARKRYKKMMEEHKALVLQKYARAWLVRRRFQTMRRLVLNVQLSYR 884 HSP 2 Score: 150.599 bits (379), Expect = 7.803e-36 Identity = 156/668 (23.35%), Postives = 313/668 (46.86%), Query Frame = 2
Query: 3608 LQMNISSLSQENNRLKETVQQFEDELLKYEQCAEDSKGLVIHN-EYDNELLSIIKDIKGMDEHGLKSRLIDEVANLKKKLKQSNEDYQKLRLHIFDGSMSKLTGNLDHESINSEEEELKRAFESQKEANRKMLKEIEGIKANNV---DLKKALFQIRKDKEQLQVQLGKQHLMIRHGVEYLQNLKLTPKERLDKFVQNEISRILLENLKLQERNDQIISETIELKRGLKYFAFRLQKYEGSLVPNPNKEEDLLQLIQNVIYH-SKMKTIGKRECYSEIGLIDLNMSELSIFIKSFIFDLSPSICLQYEPYHLVPYIIFMVTRKFDFYKEEDQMTNFLSKLIVALKRTIRKRRNYIEYLVMLLSNVFCLVNLXXXXXXXXXXXXLNTAEDIQHYFVHYDLNEFIRLLKELCVTLFQMILKTIVDNLLPQSLCIDAILVHEAI--IDFLSKDGTKYKSNI---ETQPKNTSFNV--LTKNLQSVLEILKNHKIPQLIINQIFVHIAYLINAYCLNTLLFRTDLCYFSKGLQIKYNLSSFETWIRYQKLIDSGALQCLRPMTEAVQLLQTLIDSDEDAKFVCDMCEYLNTRQVVKILNNFNPRDGYGCRLSSGLIAKIETQMKIKRGDEPSESKLETPTVIEIPIDIPFIHNGVSLCRTIIPKPLYLSCLT 5575
L+ I +L +EN R++E Q + + + Q ++ K N E + +LL ++ +R+++ +LK+ E Y + M L DH + E ++L+ F+ + + N+ + +E+ + A N+ DLK+ + + ++ +++L+ QL +Q+ + + L L + R + EI L E + E+ ++ E K L+ RL + ++ ++ +Q+ I K + +E +G+++ + ++ I +L P + L ++FM R D+ + +++ + + +I A+K+ I + E L LSN + L+N F+QYSG ++F NT ++ ++DL+E ++L +L + ++ + + D L P + + A+L HE++ I + G + +SN E + + +++V + + + S + + + Q + YLI A LN++L R DLC KG+QI+ N+S E W+R + L A++ L P+++A LLQ +DEDA + C L+ Q+VKILN++ P D + R++ + K++ ++ + G ++L + PF + +L +P L+L LT
Sbjct: 965 LEKEILALKEENRRMREEKLQLQTQASEDTQINKEMKKEAAENSENEGDLLFAFDGLQ------TATRVVE------TQLKEQRESY--------ESQMEALVFKNDH--LARENQQLQALFQEKSDVNQSIGQEVARLTAENMVIPDLKQQVAESQRHRQELETQLKEQNTEMTGELFSNNELLLEERNRESTIEREEIQGRLEELEEEMEQLKRLHQTENETKNKLRQETSRLTAENMDFEEQIDMKDRTIKRLQDQIKALQKAAQVLPKEY---LGMLEYKKEDEDKLVRMLIRELKPRGVVVNMIPGLAANLLFMCVRHSDYLNDGNKLKSLMHAIITAIKQVITDHQENFEILSFWLSNTYYLLNCFKQYSGEEEFMKHNTPRQNKNCLQNFDLSEHRQILSDLAIRIYHQFINIMEDTLFP--MIVPAMLEHESLQGISSMKPTGFRKRSNSLLEEGRSEGQAYSVSSILQLMNSFHNAMAQQGMELQLQGQAIRQLFYLIGATSLNSILLRKDLCSCRKGMQIRCNISYLEEWLREKGLQGCSAMETLGPLSQAAWLLQVNKTTDEDAAEIRQQCRELSAVQIVKILNSYTPIDDFEKRVAPSFVRKVQGLLQEREGS----NQLMMDAQYRFQVTFPFCPSTQALELLQVPSSLHLGFLT 1601
BLAST of Dach-2 vs. Ensembl Cavefish
Match: myo5c (myosin VC [Source:ZFIN;Acc:ZDB-GENE-131127-196]) HSP 1 Score: 554.673 bits (1428), Expect = 9.053e-177 Identity = 304/611 (49.75%), Postives = 403/611 (65.96%), Query Frame = 2
Query: 80 KIWIPDEESVWIGATVLQ-FHKEKNVIKIITDNGISKELNLSSKKCAPFLRNPDILIGQKDLTYLSYLNEPEVLYNLQIRFCERREIYTYCGIVLVAINPYQELSIYGKEIINAYHSQNSVDLDPHIFAVAENAFRRMSSFGENQSIIVSGESGAGKTVSAKYTMRYFALVGGSKTKQSFNLTETQIERKVLLSNPILEAFGNAKTIRNDNSSRFGKYLEILFNPRNQVIGANMCTYLLEKSRVVFQNLGERNYHIFYQIVTHCQSEDELLMNTGLVNNVEMYDYLRYGESLEIDGVDDSHEFLITKNSFLQLGIDLNKFKTICEILAAILHLGNIRFRFHDATDSSIIENPELLKLIAGLLGCSIDQLKIWLCFRTISTFQETLHKPLSKAEAQYFRDAFVKTLYSNLFDWIVKQANKVLSTDVSINIKKKLKKTIVVNQEDKKKFIAVLDIYGFETFAENSFEQFCINFANEKLQLQFNLHVFKLEQEEYMNEGLEWTFIDYYNNQPCIDLIESRXXXXXXXXXXXXXXXXSDENWCCKIYSHHLNKSANFNKPKLSNMVFIIEHFAGPVEYKCAGFIEKNRDSVLEEQINLLKASDVQLIAELFRDSE 1909
++WIPD E VW A +L+ F + + ++G + + P LRNPDIL+G+ DLT LSYL+EP VL+NL++RF + R IYTYCGI+LVA+NPY++L IYG +I+AY QN DLDPHIFAVAE A+++M+ NQSIIVSGESGAGKTVSA+Y MRYFA+V S + + ++E KVL SNPI EA GNAKT RNDNSSRFGKY EI F+ R Q+IGANM TYLLEKSRVVFQ+ ERNYH+FYQ+ C D+ + + + + ++Y G EI GVDD + T+ +F LG+ + + ++LA ILHLGN+ + + SSI + L + LLG +++ WLC R I ET+ KP K A RDA K LY+ LFD ++ + N+ L + FI VLDIYGFETF NSFEQFCIN+ANEKLQ QFNLHVFKLEQEEYM E + WT ID+Y+NQP IDLIE+++G+LDLLDEEC +G+D+NW K+Y+ +L +F KP+LSN F+I+HFA V+Y+C GF+EKNRD++ EE +++++AS L+ + F + E
Sbjct: 10 RVWIPDSEQVWKSAEILKDFSPGDPTLHLQLEDGTVLQYPVEGPGQLPHLRNPDILVGENDLTALSYLHEPAVLHNLRVRFVDSRIIYTYCGIILVAVNPYKQLPIYGDGVIHAYSGQNMGDLDPHIFAVAEEAYKQMAR--SNQSIIVSGESGAGKTVSARYAMRYFAMVSKSSSNK-------RVEDKVLASNPITEAIGNAKTTRNDNSSRFGKYTEISFDRRYQIIGANMRTYLLEKSRVVFQSENERNYHVFYQM---CACADQPEFKSLRLLSADKFNYTCMGGDTEIQGVDDCADMAETRRTFSLLGLKEDFQSDVFKMLAGILHLGNVVIKAVGSDQSSISSSDSHLVVFCDLLGVRGEEMSRWLCHRRIVLASETVVKPQPKERAINARDALAKHLYAYLFDCVILRINQALRV-----------------PGKQHSFIGVLDIYGFETFDVNSFEQFCINYANEKLQQQFNLHVFKLEQEEYMKEDIPWTLIDFYDNQPVIDLIEAKMGILDLLDEECLFPQGTDKNWLQKLYN-YLGSKPHFEKPRLSNEAFVIQHFADKVQYQCRGFLEKNRDTLYEELVDVMRASKFPLLTDFFTEEE 590
BLAST of Dach-2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000498.1 (pep scaffold:Pmarinus_7.0:GL479744:368:24152:-1 gene:ENSPMAG00000000443.1 transcript:ENSPMAT00000000498.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 692.189 bits (1785), Expect = 0.000e+0 Identity = 379/696 (54.45%), Postives = 467/696 (67.10%), Query Frame = 2
Query: 242 LIGQKDLTYLSYLNEPEVLYNLQIRFCERREIYTYCGIVLVAINPYQELSIYGKEIINAYHSQNSVDLDPHIFAVAENAFRRMSSFGENQSIIVSGESGAGKTVSAKYTMRYFALVGGSKTKQSFNLTETQIERKVLLSNPILEAFGNAKTIRNDNSSRFGKYLEILFNPRNQVIGANMCTYLLEKSRVVFQNLGERNYHIFYQIVTHCQSEDELLMNTGLVNNVEMYDYLRYGESLEIDGVDDSHEFLITKNSFLQLGIDLNKFKTICEILAAILHLGNIRFRFHDATDSSIIENPE--LLKLIAGLLGCSIDQLKIWLCFRTISTFQETLHKPLSKAEAQYFRDAFVKTLYSNLFDWIVKQANKVLSTDVSINIKKKLKKTIVVNQEDKKKFIAVLDIYGFETFAENSFEQFCINFANEKLQLQFNLHVFKLEQEEYMNEGLEWTFIDYYNNQPCIDLIESRXXXXXXXXXXXXXXXXSDENWCCKIYSHHLNKSANFNKPKLSNMVFIIEHFAGPVEYKCAGFIEKNRDSVLEEQINLLKASDVQLIAELFRDSEIEIFDTNNXXXXXXXXXXXXXXXXXXQENTRKMKKTVGSQFRNSLKSLMDALNKTNPHYVRCIKPNDLKLPFTFCPERAVQQLRACGVLETIRLSAAGFPSRWTYSDFYHRYYILMSNFNVKNHDFKAGSQKIVETLI 2323
L+G+ DLT LSYL+EP VL+NL++RF E IYTYCGIVLVAINPY++L IYG++II AY QN D+DPHIFAVAE A+++M+ +NQSIIVSGESGAGKTVSAKY MRYFA VGGS +E IE KVL SNPI+EA GNAKT RNDNSSRFGKY+EI FN + ++GANM TYLLEKSRVVFQ ERNYH+FYQ+ C S + + E + Y G + I+ VDD + T+ +F LGI + I +I+A ILHLGN+ + D + N E L + LLG DQ+ WLC R IST ET KP+ +A+AQ RDA K +Y+ LF WIV + NK L + + FI VLDIYGFETF NSFEQFCIN+ANEKLQ QFNLHVFKLEQEEYM E + WT ID+Y+NQPCIDLIE++LG+LDLLDEECK+ KGSD++W K+Y HL + +F KP++SN+ FII HFA VEY+C GF+EKNRD+V EEQIN+LKAS L+ F S + P ++ST+ T+ QFRNSL LM+ LN T PHYVRCIKPND K+ FTF P+RAVQQLRACGVLETIRLSAAG+PSRWTY +F++RY +LM ++ + D K Q ++E +I
Sbjct: 1 LVGENDLTALSYLHEPAVLHNLKVRFAESNHIYTYCGIVLVAINPYEQLPIYGEDIIFAYSGQNMGDMDPHIFAVAEEAYKQMARDEKNQSIIVSGESGAGKTVSAKYAMRYFATVGGSA-------SEANIEEKVLASNPIMEAIGNAKTTRNDNSSRFGKYIEIGFNRQYLIVGANMRTYLLEKSRVVFQAEEERNYHVFYQL---CASAELPEFKDLHLEPAEAFVYTAQGGNAVIEDVDDGEDLERTRRAFTLLGIGASYQMGIFKIIAGILHLGNVEVQSQDREQETCFVNKEDKHLNIFCELLGLERDQMAHWLCHRKISTGAETYVKPMGRAQAQNARDALAKHVYAQLFSWIVHRINKALRSSTK-----------------QHSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNLHVFKLEQEEYMREEIPWTLIDFYDNQPCIDLIEAKLGVLDLLDEECKMPKGSDQSWAQKLYEKHLGRGKHFLKPRMSNVAFIICHFADKVEYQCDGFLEKNRDTVYEEQINILKASQSSLLTLAFV-SRPPCLHPTGTPPPRRRRNSTEGNRHRSSARTKARSHVATFQFRNSLHLLMETLNATTPHYVRCIKPNDDKMAFTFDPKRAVQQLRACGVLETIRLSAAGYPSRWTYQEFFNRYRVLMRKKDIVSDDKKQTVQNVLEHVI 668
BLAST of Dach-2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000499.1 (pep scaffold:Pmarinus_7.0:GL479744:9258:25467:-1 gene:ENSPMAG00000000443.1 transcript:ENSPMAT00000000499.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 595.89 bits (1535), Expect = 0.000e+0 Identity = 325/601 (54.08%), Postives = 409/601 (68.05%), Query Frame = 2
Query: 77 VKIWIPDEESVWIGATVLQFHKEKN-VIKIITDNGISKELNLSSKKCAPFLRNPDILIGQKDLTYLSYLNEPEVLYNLQIRFCERREIYTYCGIVLVAINPYQELSIYGKEIINAYHSQNSVDLDPHIFAVAENAFRRMSSFGENQSIIVSGESGAGKTVSAKYTMRYFALVGGSKTKQSFNLTETQIERKVLLSNPILEAFGNAKTIRNDNSSRFGKYLEILFNPRNQVIGANMCTYLLEKSRVVFQNLGERNYHIFYQIVTHCQSEDELLMNTGLVNNVEMYDYLRYGESLEIDGVDDSHEFLITKNSFLQLGIDLNKFKTICEILAAILHLGNIRFRFHDATDSSIIENPE--LLKLIAGLLGCSIDQLKIWLCFRTISTFQETLHKPLSKAEAQYFRDAFVKTLYSNLFDWIVKQANKVLSTDVSINIKKKLKKTIVVNQEDKKKFIAVLDIYGFETFAENSFEQFCINFANEKLQLQFNLHVFKLEQEEYMNEGLEWTFIDYYNNQPCIDLIESRXXXXXXXXXXXXXXXXSDENWCCKIYSHHLNKSANFNKPKLSNMVFIIEHFAGPVEYKCAGFIEKNRDSVLEEQINLLKAS 1870
K+WIP + VW+ A + Q +++ + ++++ ++G + L + P LRNPDIL+G+ DLT LSYL+EP VL+NL++RF E IYTYCGIVLVAINPY++L IYG++II AY QN D+DPHIFAVAE A+++M+ +NQSIIVSGESGAGKTVSAKY MRYFA VGGS +E IE KVL SNPI+EA GNAKT RNDNSSRFGKY+EI FN + ++GANM TYLLEKSRVVFQ ERNYH+FYQ+ C S + + E + Y G + I+ VDD + T+ +F LGI + I +I+A ILHLGN+ + D + N E L + LLG DQ+ WLC R IST ET KP+ +A+AQ RDA K +Y+ LF WIV + NK L + + FI VLDIYGFETF NSFEQFCIN+ANEKLQ QFNLHVFKLEQEEYM E + WT ID+Y+NQPCIDLIE++LG+LDLLDEECK+ KGSD++W K+Y HL + +F KP++SN+ FII HFA VEY+C GF+EKNRD+V EEQIN+LKAS
Sbjct: 14 TKVWIPHADEVWVSAEICQDYRDGDRLLQLRLEDGRVVQHPLEGGQLPP-LRNPDILVGENDLTALSYLHEPAVLHNLKVRFAESNHIYTYCGIVLVAINPYEQLPIYGEDIIFAYSGQNMGDMDPHIFAVAEEAYKQMARDEKNQSIIVSGESGAGKTVSAKYAMRYFATVGGSA-------SEANIEEKVLASNPIMEAIGNAKTTRNDNSSRFGKYIEIGFNRQYLIVGANMRTYLLEKSRVVFQAEEERNYHVFYQL---CASAELPEFKDLHLEPAEAFVYTAQGGNAVIEDVDDGEDLERTRRAFTLLGIGASYQMGIFKIIAGILHLGNVEVQSQDREQETCFVNKEDKHLNIFCELLGLERDQMAHWLCHRKISTGAETYVKPMGRAQAQNARDALAKHVYAQLFSWIVHRINKALRSSTK-----------------QHSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNLHVFKLEQEEYMREEIPWTLIDFYDNQPCIDLIEAKLGVLDLLDEECKMPKGSDQSWAQKLYEKHLGRGKHFLKPRMSNVAFIICHFADKVEYQCDGFLEKNRDTVYEEQINILKAS 586
BLAST of Dach-2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004078.1 (pep scaffold:Pmarinus_7.0:GL478761:5289:25008:-1 gene:ENSPMAG00000003722.1 transcript:ENSPMAT00000004078.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 473.011 bits (1216), Expect = 3.475e-143 Identity = 299/832 (35.94%), Postives = 458/832 (55.05%), Query Frame = 2
Query: 230 NPDILIGQKDLTYLSYLNEPEVLYNLQIRFCERREIYTYCGIVLVAINPYQELSIYGKEIINAYHSQNSVDLDPHIFAVAENAFRRMSSFGENQSIIVSGESGAGKTVSAKYTMRYFALVGGSKTKQSFNLTETQIERKVLLSNPILEAFGNAKTIRNDNSSRFGKYLEILFNPRNQVIGANMCTYLLEKSRVVFQNLGERNYHIFYQIVTHCQSEDELLMNTGLVNNVEMYDYLRYGESLEIDGVDDSHEFLITKNSFLQLGIDLNKFKTICEILAAILHLGNIRFRFHDATDSSIIENPELLKLIAGLLGCSIDQLKIWLCFRTISTFQETLHKPLSKAEAQYFRDAFVKTLYSNLFDWIVKQANKVLSTDVSINIKKKLKKTIVVNQEDKKKFIAVLDIYGFETFAENSFEQFCINFANEKLQLQFNLHVFKLEQEEYMNEGLEWTFIDYYNN-QPCIDLIESRXXXXXXXXXXXXXXXXSDENWCCKIYSHHLNKSANFNKPKL----SNMVFIIEHFAGPVEYKCAGFIEKNRDSVLEEQINLLKASDVQLIAELFRDSEIEIFDTNNXXXXXXXXXXXXXXXXXXQENTRKMKKTVGSQFRNSLKSLMDALNKTNPHYVRCIKPNDLKLPFTFCPERAVQQLRACGVLETIRLSAAGFPSRWTYSDFYHRYYILMSNFNVKNH--DFKAGSQKIVETLITVPDAFRFGNTKLFFRPGQVALLEKLRGHKIESSVTLIQSILRGSIERKKYLIIHKLTVQIQTYIRRKLAIEKATKLSQIRAVIIIQSFYRMYLARKLFVKMKCAVLAIEKWRRKIITTRLKQAYKK 2704
NP +D+ L++LNEP VL+NL+ R+ IYTY G+ V +NPY+ L +Y + +NAY + + PHIF+++ S+ ENQSI+++GESGAGKTV+ K ++YFA + + TK+ + ++ +E +++ +NP LEAFGNAKT+RNDNSSRFGK++ I F ++ A++ T LEKSRV FQ ERNYHIFYQI++ Q + ELL + +N Y ++ G+ + + G+DD E + T +++ LG + ++ ++ AI+H GN+ F+ + + + E + L+G + L LC + E + K + + Y A K++Y +F+W+V + N+ L T ++ FI VLDI GFE F NSFEQ CINF NEKLQ FN H+F LEQEEY EG+EWTFID+ + Q CI+LIE +G++ +L+EEC K SD+++ K+Y +HL KS NF KP++ F + H+AG V+Y +G++ KN+D + E + L + S ++L+A LF + + S + +TV + R +L LM L T+PH+VRCI PN+ K P + QLR GVLE IR+ GFPSR Y DF HRY IL N + D + ++K++ TL ++FG+TK+FF+ G + LE++R ++ +TL+Q+ RG + RK++ I I R+ A+ IRA + ++++ M L K+ +K A E K +LK+AY K
Sbjct: 78 NPPKFDKIEDMAMLTFLNEPSVLFNLKERYAAWM-IYTYSGLFCVTVNPYKWLPVYSSQCVNAYRGKKRQEAPPHIFSISLYISDLHSADRENQSILITGESGAGKTVNTKRVIQYFASIAAAGTKR--DASKGTLEDQIVSANPALEAFGNAKTLRNDNSSRFGKFIRIHFGTTGKLASADIET--LEKSRVTFQLKAERNYHIFYQILS--QRKPELLEMLLVTSNPYDYAFISQGQ-VTVAGLDDGDELMATDSAYDILGFVPEEKASVYKLTGAIMHFGNMHFKQKQREEQAEADGTEDADKASYLMGLNSADLIKGLCHPRVKVGNEYVTKGQNVQQVSYSIGALAKSVYEKMFNWMVVRINQSLETKAP-----------------RQHFIGVLDIAGFEIFDFNSFEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLQACIELIEKPMGIMSILEEECMFPKASDQSFKAKLYDNHLGKSNNFQKPRIVKGKPEAHFALVHYAGVVDYNISGWLVKNKDPLNETVVGLYQKSSLKLLASLFAN--------------YAGADSAADTSKKGAKKKGSSFQTVSALHRENLNKLMTNLRSTHPHFVRCIIPNEEKKPGAMDNALVMHQLRCNGVLEGIRICRKGFPSRILYGDFTHRYRILNPNAVPEGQFMDSRKSAEKLLSTLDIDHTQYKFGHTKVFFKAGLLGTLEEMRDDRLSKIITLLQARCRGLLSRKEFAKI----------IERRDAL--LVIQYNIRAFMGVKNWPWMKLFFKIKPLLKSAETEKEMQNMKEDFLKLKEAYAK 858
BLAST of Dach-2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000005411.1 (pep scaffold:Pmarinus_7.0:GL476612:1285:44967:1 gene:ENSPMAG00000004885.1 transcript:ENSPMAT00000005411.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 460.299 bits (1183), Expect = 1.371e-138 Identity = 291/831 (35.02%), Postives = 446/831 (53.67%), Query Frame = 2
Query: 86 WIPDEESVWIGATVLQFHKEKNV-IKIITDNGISKELNLSSKKCAPFLRNPDILIGQKDLTYLSYLNEPEVLYNLQIRFCERREIYTYCGIVLVAINPYQELSIYGKEIINAYHSQNSVDLDPHIFAVAENAFRRM--SSFGENQSIIVSGESGAGKTVSAKYTMRYFALVGGSKTKQSFNLTETQIERKVLLSNPILEAFGNAKTIRNDNSSRFGKYLEILFNPRNQVIGANMCTYLLEKSRVVFQNLGERNYHIFYQIVTHCQSEDELLMNTGLVNNVEMYDYLRYGESLEIDGVDDSHEFLITKNSFLQLGIDLNKFKTICEILAAILHLGNIRFRFHDATDSSIIENPELLKLIAGLLGCSIDQLKIWLCFRTISTFQETLHKPLSKAEAQYFR-------DAFVKTLYSNLFDWIVKQANKVLSTDVSINIKKKLKKTIVVNQEDKKKFIAVLDIYGFETFAENSFEQFCINFANEKLQLQFNLHVFKLEQEEYMNEGLEWTFIDY-YNNQPCIDLIESRXXXXXXXXXXXXXXXXSDENWCCKIYSHHLNKSANFNKPKLSN-----MVFIIEHFAGPVEYKCAGFIEKNRDSVLEEQINLLKASDVQLIAELFRDSEIEIFDTNNXXXXXXXXXXXXXXXXXXQENTRKMKKTVGSQFRNSLKSLMDALNKTNPHYVRCIKPNDLKLPFTFCPERAVQQLRACGVLETIRLSAAGFPSRWTYSDFYHRYYILMSNFNVKNHDFKAGSQKIVETLITVPDAFRFGNTKLFFRPGQVALLEKLRGHKIESSVTLIQSILRGSIERK---KYLIIHKLTVQIQTYIR 2521
W+ DE+ ++ A + H + V +K +N I+K KK NP +D+ L++LNE VL NL+ R+ + R IYTY G+ V INPY+ L IYG + Y + ++ PH+F++++NA+ M ++ NQS++++GESGAGKT + K ++YFA +GG TKQ + +E +++ +NP+LEAFGNAKT RN+NSSRFGK++ I F ++ GA++ TYLLEKSRV+ Q ER YHIFYQ+++ LL GLVNN + Y + G + ++ +DD+ E ++T +F LG + ++ ++ I+H GN++FR + + ++ E+ +A L G +L+ + + E + K + + + A K +Y +F W+V + NK L T + ++ FI VLDI GFE F NSFEQ CINF NEKLQ FN H+F LEQEEY EG+ W FID+ + CIDL+E +G+ +L+E+C K +D + +Y +HL KSA F KPK F + H+AG V Y G++EKN+D + E ++L + S + L++ LF++ E + S + +++ +TV +R L LM L+ T+PH+VRCI PN+ K + QL GVLE IR+ GFP+R Y +F RY I+ D KA ++K++++ V D +R G TK+FFR G + LE R I +T +Q+ RG + R+ K L V IQ+ +R
Sbjct: 36 WVKDEKEGFLQALIQDDHGDNTVSVKFTVNNEIAK-----VKKDIVQEMNPPKFEQIEDMANLTFLNEASVLNNLKERYVKMR-IYTYSGLFCVTINPYKWLPIYGSRVAKMYRGKKRNEVPPHLFSISDNAYSDMLITADKANQSMLITGESGAGKTENTKKVIQYFANIGGG-TKQIDQSKQGSLEDQIIQANPVLEAFGNAKTTRNNNSSRFGKFIRIHFAVSGKLSGADIETYLLEKSRVISQQPAERGYHIFYQLLSG--KVPNLLEEIGLVNNPKEYASISQGVT-SVENMDDAEEMMLTDEAFDVLGFTPEEKMSLYKLTGGIMHFGNMKFRQKPREEQAEVDGTEVADRVASLAGIDSSELQKGITRPKVKVGNEYVQKNQNMDQVYHLPQKCMSSIGALAKAIYDRMFKWLVARVNKTLDT-----------------TKPRQYFIGVLDIAGFEIFEFNSFEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGINWVFIDFGLDLAACIDLLEKPMGIFSILEEQCVFPKATDATFKAAMYDNHLGKSAPFQKPKAGKKAGQEATFELVHYAGTVGYNTQGWLEKNKDPLNETVVSLFQNSSMPLLSVLFKEEE---------------AADASSAGAKQKQKKGSAFQTVSVFYREQLNKLMATLHSTSPHFVRCIVPNEFKKSGVVDAHLILHQLACNGVLEGIRICRKGFPNRTLYPEFVQRYSIINLLAGKTETDPKAITEKVLKSTNLVEDEYRIGFTKVFFRAGVLGKLEDFRDDCICRFITKLQASCRGKVFRRDFQKVLDKRDAMVIIQSNVR 824
BLAST of Dach-2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002731.1 (pep scaffold:Pmarinus_7.0:GL478284:11062:40470:1 gene:ENSPMAG00000002428.1 transcript:ENSPMAT00000002731.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 464.537 bits (1194), Expect = 1.823e-134 Identity = 299/839 (35.64%), Postives = 457/839 (54.47%), Query Frame = 2
Query: 230 NPDILIGQKDLTYLSYLNEPEVLYNLQIRFCERREIYTYCGIVLVAINPYQELSIYGKEIINAYHSQNSVDLDPHIFAVAENAFRRMSSFGENQSIIVSGESGAGKTVSAKYTMRYFALVGGSKTKQSFNLTETQIERKVLLSNPILEAFGNAKTIRNDNSSRFGKYLEILFNPRNQVIGANMC------TYLLEKSRVVFQNLGERNYHIFYQIVTHCQSEDELLMNTGLVNNVEMYDYLRYGESLEIDGVDDSHEFLITKNSFLQLGIDLNKFKTICEILAAILHLGNIRFRFHDATDSSIIENPELLKLIAGLLGCSIDQLKIWLCFRTISTFQETLHKPLSKAEAQYFRDAFVKTLYSNLFDWIVKQANKVLSTDVSINIKKKLKKTIVVNQEDKKKFIAVLDIYGFETFAENSFEQFCINFANEKLQLQFNLHVFKLEQEEYMNEGLEWTFIDYYNN-QPCIDLIESRXXXXXXXXXXXXXXXXSDENWCCKIYSHHLNKSANFNKPKL----SNMVFIIEHFAGPVEYKCAGFIEKNRDSVLEEQINLLKASDVQLIAELFRDSEIEIFDTNNXXXXXXXXXXXXXXXXXXQENTRKMKKTVGSQFRNSLKSLMDALNKTNPHYVRCIKPNDLKLPFTFCPERAVQQLRACGVLETIRLSAAGFPSRWTYSDFYHRYYILMSNFNVKNHDF---KAGSQKIVETLITVPDAFRFGNTKLFFRPGQVALLEKLRGHKIESSVTLIQSILRGSIERKKYLIIHKLTVQIQTYIRRKLAIEKATKLSQIRAVIIIQSFYRMYLARKLFVKMKCAVLAIEKWRRKIITTRLKQAYKK 2704
NP +D+ L++LNEP VL+NL+ R+ IYTY G+ V +NPY+ L +Y + +NAY + + PHIF++++NA++ M S ENQS++++GESGAGKTV+ K ++YFA + + TK+ + ++ +E +++ +NP LEAFGNAKT+RNDNSSRF Y+ +L +N+C +LLEKSRV FQ ERNYHIFYQI++ Q + ELL + N Y ++ G+ + + G+DD E + T ++F LG + ++ ++ AI+H GN+ F+ + + + E + L+G + L LC + E + K + Y A K++Y +F+W+V + N+ L T ++ FI VLDI GFE F NSFEQ CINF NEKLQ FN H+F LEQEEY EG+EW FID+ + Q CI+LIE +G++ +L+EEC K SD+++ K+Y +HL KS NF KP++ F + H+AG V+Y +G++ KN+D + E + L + S ++L++ LF + D SS +TV + R +L LM L T+PH+VRCI PN+ K P + QLR GVLE IR+ GFP+R Y DF R Y +++ V F + ++K++ TL ++FG+TK+FF+ G + LE+LR ++ +TL+QS RG + RK++ I I R+ A+ IRA + ++++ M L K+ +K A E K +LK+AY K
Sbjct: 78 NPPKFDKIEDMAMLTFLNEPSVLFNLKERYAAWM-IYTYSGLFCVTVNPYKWLPVYSSQCVNAYRGKKRQEAPPHIFSISDNAYQYMLSDRENQSVLITGESGAGKTVNTKRVIQYFASIAAAGTKR--DASKGTLEDQIVSANPALEAFGNAKTLRNDNSSRFTTYVFVL---------SNVCLSVHLSLHLLEKSRVTFQLKAERNYHIFYQILS--QRKPELLEMLLVTTNPYDYSFISQGQ-VTVAGMDDGDELMATDSAFDILGFTAEEKASVYKLTGAIMHFGNMHFKQKQREEQAEADGTEDADKASYLMGLNSADLIKGLCHPRVKVGNEYVTKGQDVQQVSYSIGALAKSVYEKMFNWMVVRINQSLETKAP-----------------RQHFIGVLDIAGFEIFDFNSFEQICINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWVFIDFGMDLQACIELIEKPMGIMSILEEECMFPKASDQSFKAKLYDNHLGKSNNFQKPRIVKGRPEAHFALMHYAGVVDYNISGWLIKNKDPLNETVVGLYQKSSLKLLSVLFANYAAADADAAKKGGAKKKGSSF---------------QTVSALHRENLNKLMTNLRSTHPHFVRCIIPNEEKKPGAMDNALVMHQLRCNGVLEGIRICRKGFPNRILYGDFKQRQYRILNPNAVPEGQFMDSRKSAEKLLSTLDIDHTQYKFGHTKVFFKAGLLGTLEELRDDRLSKIITLMQSQCRGFLSRKEFAKI----------IERRDAL--LVIQYNIRAFMGVKNWPWMKLFFKIKPLLKSAETEKEMQNMKEDFLKLKEAYAK 857
BLAST of Dach-2 vs. Ensembl Yeast
Match: MYO2 (Type V myosin motor involved in actin-based transport of cargos; required for the polarized delivery of secretory vesicles, the vacuole, late Golgi elements, peroxisomes, and the mitotic spindle; MYO2 has a paralog, MYO4, that arose from the whole genome duplication [Source:SGD;Acc:S000005853]) HSP 1 Score: 683.33 bits (1762), Expect = 0.000e+0 Identity = 409/983 (41.61%), Postives = 596/983 (60.63%), Query Frame = 2
Query: 74 GVKIWIPDEESVWIGATVL--QFHKEKNVIKI-ITDNGI----SKELNLSSKKCAPFLRNPDILIGQKDLTYLSYLNEPEVLYNLQIRFCERREIYTYCGIVLVAINPYQELS-IYGKEIINAYHSQNSVDLDPHIFAVAENAFRRMSSFGENQSIIVSGESGAGKTVSAKYTMRYFALV---GGSKTKQSFNLTETQIERKVLLSNPILEAFGNAKTIRNDNSSRFGKYLEILFNPRNQVIGANMCTYLLEKSRVVFQNLGERNYHIFYQIVTH--CQSEDELLMNTGLVNNVEMYDYLRYGESLEIDGVDDSHEFLITKNSFLQLGIDLNKFKTICEILAAILHLGNIRFRFHDATDSSIIENPELLKLIAGLLGCSIDQLKIWLCFRTISTFQETLHKPLSKAEAQYFRDAFVKTLYSNLFDWIVKQANKVLSTDVSINIKKKLKKTIVVNQEDKKKFIAVLDIYGFETFAENSFEQFCINFANEKLQLQFNLHVFKLEQEEYMNEGLEWTFIDYYNNQPCIDLIESRXXXXXXXXXXXXXXXXSDENWCCKIYSHHLNKSAN---FNKPKLSNMVFIIEHFAGPVEYKCAGFIEKNRDSVLEEQINLLKASDVQLIAELFRDSEIEIFDTNNXXXXXXXXXXXXXXXXXXQENTRKMKKTVGSQFRNSLKSLMDALNKTNPHYVRCIKPNDLKLPFTFCPERAVQQLRACGVLETIRLSAAGFPSRWTYSDFYHRYYILMSN------FNVKN---HDFKAGSQKIVETLITVPDAFRFGNTKLFFRPGQVALLEKLRGHKIESSVTLIQSILRGSIERKKYLIIHKLTVQIQTYIRRKLAIEKATKLSQIRAVIIIQSFYRMYLARK-LFVKMKCAVLAIEKWRRKIITTRLKQAYKKENCVIICQAIVRRFIQRRKFLKIQRGVILIQNHYRRRKAKETLKILKIEARSINHIKFVNKGLENKIIELTQKLDTKEKE 2944
G + W P +E WIGA V+ +F+ K +++ + D+ I +K+LN + P LRNP IL +DLT LSYLNEP VL+ ++ R+ + IYTY GIVL+A NP+ + +Y +++I AY + +L+PH+FA+AE A+R M + +NQ+I+VSGESGAGKTVSAKY MRYFA V + + ++ET E+K+L +NPI+EAFGNAKT RNDNSSRFGKYLEILF+ +IGA + TYLLE+SR+V+Q ERNYHIFYQ++ Q+++EL + + Y Y+ G +I+G+DD+ E+ IT ++ +GI I +ILAA+LH+GNI + D+S+ + LKL LLG W+ + I T E + L+ ++A +D+ K +YS LFDW+V+ N VL + ++N + FI VLDIYGFE F +NSFEQFCIN+ANEKLQ +FN HVFKLEQEEY+ E +EW+FI++ +NQPCIDLIE++LG+L LLDEE +L GSDE+W K+Y L+KS F+KP+ FI+ H+A V Y GFIEKNRD+V + + +LKAS + + + E + ++ T K T+GS F+ SL LM+ +N TN HY+RCIKPN K + F + QLRACGVLETIR+S AGFPSRWT+ +F RYYIL+ + F K D + + I++ + ++ GNTK+FF+ G +A LEKLR +K+ +S+ +IQ +R RK+YL I + +Q I+ + ++ ++ ++Q+ YR + R +F ++ +K R+++ +LKQ ++ N + Q+ VR F R +FL+ ++ +++Q+ RRR A+ LK LK +A+S+NH+K V+ LENK+IELTQ L +K KE
Sbjct: 6 GTRCWYPHKELGWIGAEVIKNEFNDGKYHLELQLEDDEIVSVDTKDLNNDKDQSLPLLRNPPILEATEDLTSLSYLNEPAVLHAIKQRYSQLN-IYTYSGIVLIATNPFDRVDQLYTQDMIQAYAGKRRGELEPHLFAIAEEAYRLMKNDKQNQTIVVSGESGAGKTVSAKYIMRYFASVEEENSATVQHQVEMSET--EQKILATNPIMEAFGNAKTTRNDNSSRFGKYLEILFDKDTSIIGARIRTYLLERSRLVYQPPIERNYHIFYQLMAGLPAQTKEELHLT-----DASDYFYMNQGGDTKINGIDDAKEYKITVDALTLVGITKETQHQIFKILAALLHIGNIEIK-KTRNDASLSADEPNLKLACELLGIDAYNFAKWVTKKQIITRSEKIVSNLNYSQALVAKDSVAKFIYSALFDWLVENINTVLC-NPAVN-------------DQISSFIGVLDIYGFEHFEKNSFEQFCINYANEKLQQEFNQHVFKLEQEEYVKEEIEWSFIEFNDNQPCIDLIENKLGILSLLDEESRLPAGSDESWTQKLY-QTLDKSPTNKVFSKPRFGQTKFIVSHYALDVAYDVEGFIEKNRDTVSDGHLEVLKASTNETLINILEGLEKA---AKKLEEAKKLELEQAGSKKPGPIRTVNRKPTLGSMFKQSLIELMNTINSTNVHYIRCIKPNADKEAWQFDNLMVLSQLRACGVLETIRISCAGFPSRWTFEEFVLRYYILIPHEQWDLIFKKKETTEEDIISVVKMILDATVKDKSKYQIGNTKIFFKAGMLAYLEKLRSNKMHNSIVMIQKKIRAKYYRKQYLQISQAIKYLQNNIKGFIIRQRVNDEMKVNCATLLQAAYRGHSIRANVFSVLRTITNLQKKIRKELKQRQLKQEHEY-NAAVTIQSKVRTFEPRSRFLRTKKDTVVVQSLIRRRAAQRKLKQLKADAKSVNHLKEVSYKLENKVIELTQNLASKVKE 960 HSP 2 Score: 60.4622 bits (145), Expect = 3.199e-9 Identity = 33/164 (20.12%), Postives = 79/164 (48.17%), Query Frame = 2
Query: 4883 CIDAILVHEAIIDFLSKDGTKYKSNIETQPKNTSFNVLTKNLQSVLEILKNHKIPQLIINQIFVHIAYLINAYCLNTLLFRTDLCYFSKGLQIKYNLSSFETWIRYQKLIDSGALQCLRPMTEAVQLLQTLIDSDEDAKFVCDMCEYLNTRQVVKILNNFNPRD 5374
I+A+++ E++ F + + + + + I + + + + S+ +K+ I + + + + ++A C N L+ + + + +GLQ+ YN++ E W + L D +CL+ + + +LLQ + ED + +C L Q+ K+++ + D
Sbjct: 1321 AINAVVISESLPGFSAGETSGFLNKIFANTEEYTMDDILTFFNSIYWCMKSFHIENEVFHAVVTTLLNYVDAICFNELIMKRNFLSWKRGLQLNYNVTRLEEWCKTHGLTD--GTECLQHLIQTAKLLQVRKYTIEDIDILRGICYSLTPAQLQKLISQYQVAD 1482
BLAST of Dach-2 vs. Ensembl Yeast
Match: MYO4 (Type V myosin motor involved in actin-based transport of cargos; required for mRNA transport, including ASH1 mRNA, and facilitating the growth and movement of ER tubules into the growing bud along with She3p; MYO4 has a paralog, MYO2, that arose from the whole genome duplication [Source:SGD;Acc:S000000027]) HSP 1 Score: 617.461 bits (1591), Expect = 0.000e+0 Identity = 383/972 (39.40%), Postives = 552/972 (56.79%), Query Frame = 2
Query: 74 GVKIWIPDEESVWIGATVLQ-------FHKEKNVIKIITDNGISKELNL----SSKKCAPFLRNPDILIGQKDLTYLSYLNEPEVLYNLQIRFCERREIYTYCGIVLVAINPYQELS-IYGKEIINAYHSQNSVDLDPHIFAVAENAFRRMSSFGENQSIIVSGESGAGKTVSAKYTMRYFALVGGSKTKQSFNLTETQIERKVLLSNPILEAFGNAKTIRNDNSSRFGKYLEILFNPRNQVIGANMCTYLLEKSRVVFQNLGERNYHIFYQIVTHCQSEDELLMNTGLVNNVEMYDYLRYGESLEIDGVDDSHEFLITKNSFLQLGIDLNKFKTICEILAAILHLGNIRFRFHDATDSSIIENPELLKLIAGLLGCSIDQLKIWLCFRTISTFQETLHKPLSKAEAQYFRDAFVKTLYSNLFDWIVKQANKVLSTDVSINIKKKLKKTIVVNQEDKKKFIAVLDIYGFETFAENSFEQFCINFANEKLQLQFNLHVFKLEQEEYMNEGLEWTFIDYYNNQPCIDLIESRXXXXXXXXXXXXXXXXSDENWCCKIYSHHLNKSAN--FNKPKLSNMVFIIEHFAGPVEYKCAGFIEKNRDSVLEEQINLLKASDVQLIAELFRDSEIEIFDTNNXXXXXXXXXXXXXXXXXXQENTRK----------MKKTVGSQFRNSLKSLMDALNKTNPHYVRCIKPNDLKLPFTFCPERAVQQLRACGVLETIRLSAAGFPSRWTYSDFYHRYYIL---------MSNFNVKNHDFKAGSQKIVETLITVPDAFRFGNTKLFFRPGQVALLEKLRGHKIESSVTLIQSILRGSIERKKYLIIHKLTVQIQTYIRRKLAIEKATKLSQIRAVIIIQSFYRMYLARKLF-------VKMKCAVLAIEKWRRKIITTRLKQAYKKENCVIICQAIVRRFIQRRKFLKIQRGVILIQNHYRRRKAKETLKILK--IEARSI 2863
G K W P +E WIG V + FH E +K+ +S E N P LRNP IL DLT LSYLNEP VL+ ++ R+ +IYTY GIVL+A NP+ ++ +Y +E+I Y S+ +L+PH+FA+AE A+R M NQ+++VSGESGAGKTVSAKY MRYFA V S ++ + +QIE ++L +NPI+EAFGNAKT RNDNSSRFGKYL+ILF+ + G+ + TYLLEKSR+V+Q ERNYHIFYQI+ + E + +++ + Y Y G I G+D++ E+ IT ++ +GI+ I +ILA +LH+GNI + D+S+ + L++ LLG W+ + I T E + L+ +A RD+ K +YS LFDW+V NI K L + Q+ FI +LDIYGFE F +NSFEQFCIN+ANEKLQ +FN HVFKLEQEEY+ E +EW+FI++ +NQPCIDLIE++LG+L LLDEE +L GSDE+W K+YS +N F+KP+ FI+ H+A VEY+ GFIEKNRDSV +++ KA+ + ++ + E+ D +++NT K K T+GS F+ SL LM +N TN HY+RCIKPN K P+ F + QLRACGVLETIR+S AGFPSRWT+ +F RY++L + N ++ Q I++ I+ ++ GNTK+FF+ G +A LEKLR +K+ +IQ +R R +YL + + Q+ IR L + + RA I++Q+ R R+ + +K++C +RK+I + + + VII Q+ +R + + + ++R IL+Q+ R + A+ +L+ +E R+I
Sbjct: 6 GTKCWYPHKEQGWIGGEVTKNDFFEGTFHLE---LKLEDGETVSIETNSFENDDDHPTLPVLRNPPILESTDDLTTLSYLNEPAVLHAIKKRYM-NGQIYTYSGIVLIAANPFDKVDHLYSREMIQNYSSKRKDELEPHLFAIAEEAYRFMVHEKANQTVVVSGESGAGKTVSAKYIMRYFASVQESNNREG-EVEMSQIESQILATNPIMEAFGNAKTTRNDNSSRFGKYLQILFDENTTIRGSKIRTYLLEKSRLVYQPETERNYHIFYQIL---EGLPEPVKQELHLSSPKDYHYTNQGGQPNIAGIDEAREYKITTDALSLVGINHETQLGIFKILAGLLHIGNIEMKM-TRNDASLSSEEQNLQIACELLGIDPFNFAKWIVKKQIVTRSEKIVTNLNYNQALIARDSVAKFIYSTLFDWLVD------------NINKTLYDPELDQQDHVFSFIGILDIYGFEHFEKNSFEQFCINYANEKLQQEFNQHVFKLEQEEYVKEEIEWSFIEFSDNQPCIDLIENKLGILSLLDEESRLPSGSDESWASKLYSAFNKPPSNEVFSKPRFGQTKFIVSHYAVDVEYEVEGFIEKNRDSVSLGHLDVFKATTNPIFKQILDNRELRSDDA------------------PEEQNTEKKIMIPARLSQKKPTLGSMFKKSLGELMAIINSTNVHYIRCIKPNSEKKPWEFDNLMVLSQLRACGVLETIRISCAGFPSRWTFDEFVQRYFLLTDYSLWSGILYNPDLPKEAIVNFCQSILDATISDSAKYQIGNTKIFFKAGMLAFLEKLRTNKMNEICIIIQKKIRARYYRLQYLQTMESIKKCQSQIRSLLVRTRVDHELKTRAAILLQTNIRALWKREYYRAAIGQIIKLQCTC------KRKLILDSVNRKFMLMAAVII-QSYIRSYGHKTDYRTLKRSSILVQSAMRMQLARRRYIVLQKEVEERNI 931
BLAST of Dach-2 vs. Ensembl Yeast
Match: MYO1 (Type II myosin heavy chain; required for wild-type cytokinesis and cell separation; localizes to the actomyosin ring; binds to myosin light chains Mlc1p and Mlc2p through its IQ1 and IQ2 motifs respectively [Source:SGD;Acc:S000001065]) HSP 1 Score: 419.853 bits (1078), Expect = 5.423e-120 Identity = 304/854 (35.60%), Postives = 464/854 (54.33%), Query Frame = 2
Query: 68 SKGVKIWIPDEESVWIGATVL-------QFHKEKNVIKIITDNGISKELNLSSKKCAP-FLRNPDILIGQKDLTYLSYLNEPEVLYNLQIRF-CERREIYTYCGIVLVAINPYQELSIYGKEIINAYH------SQNSVD------LDPHIFAVAENAFRRMSSFGENQSIIVSGESGAGKTVSAKYTMRYFAL-----------VGGSKTKQSFNLTETQIERKVLLSNPILEAFGNAKTIRNDNSSRFGKYLEILFNPRNQVIGANMCTYLLEKSRVVFQNLGERNYHIFYQIVTHCQSEDELLMNTGLVN-NVEMYDYLRYGESLEIDGVDDSHEFLITKNSFLQLGIDLNKFKTICEILAAILHLGNIRFRFHDATDSSIIENPELLKLIAGLLGCSIDQLKIWLCFRTISTFQETLHKPLSKAEAQYFRDAFVKTLYSNLFDWIVKQANKVLS-TDVSINIKKKLKKTIVVNQEDKKKFIAVLDIYGFETFAENSFEQFCINFANEKLQLQFNLHVFKLEQEEYMNEGLEWTFIDYYNN-QPCIDLIESR---XXXXXXXXXXXXXXXXSDENWCCKIYSHHLNKSANFNKPKLSNMVFIIEHFAGPVEYKCAGFIEKNRDSVLEEQINLLKASDVQLIAELFRDSEIEIFDTNNXXXXXXXXXXXXXXXXXXQENTRKMK----KTVGSQFRNSLKSLMDALNKTNPHYVRCIKPNDLKLPFTFCPERAVQQLRACGVLETIRLSAAGFPSRWTYSDFYHRYYIL------MSNFNVKNHDFKAGSQKIVETLITV----PDAFRFGNTKLFFRPGQVALLEKLRGHKIESSVTLIQSILRGSIERKK 2473
S + +WIPDE+ V++ ++ +F ++ I I+ ++ NL + + F NP ++++ L++LNEP VLYNL+ R+ C+ IYTY G+ LVAINPY L++Y ++ IN YH S++ +D L PHIFA+AE A+ + S G++QSI+V+GESGAGKT + K ++Y A V GS +SF E K+L SNPILE+FGNA+T+RN+NSSRFGK+++I FN + GA++ YLLEKSR+V QN ERNYHIFYQ+++ +D L N L + NV+ Y L I G++D F ++ +G ++ + I +++A IL +GNI F D + + +N + I LG + + +E + + + +A++ +A + LY LF +IV NK L ++N +I +LDI GFE F NSFEQ CIN+ NEKLQ FN H+F LEQ EY+ E ++W +IDY + Q IDLIES+ G+L LLDEE L K +DE++ K+ S S+ F + +L N FI++H+AG VEY G++ KN+D + + ++LL +S +I++LF+ S+ QE + + KT S+ R +L++ L T+PH+VRCI PN++K TF + QLR GVLE IRL+ G+P+R + +F+ RY IL + F+ K KA +++ E L+T ++ GNTKLFF+ G +A LEK + K+ + + + + +RG RK+
Sbjct: 8 SSNMIVWIPDEKEVFVKGELMSTDINKNKFTGQEEQIGIVHPLDSTEVSNLVQVRISDVFPVNPSTFDKVENMSELTHLNEPSVLYNLEKRYDCDL--IYTYSGLFLVAINPYHNLNLYSEDHINLYHNKHNRLSKSRLDENSHEKLPPHIFAIAEEAYENLLSEGKDQSILVTGESGAGKTENTKKILQYLASITSGSPSNIAPVSGSSIVESF-------EMKILQSNPILESFGNAQTVRNNNSSRFGKFIKIEFNEHGMINGAHIEWYLLEKSRIVHQNSKERNYHIFYQLLSGL--DDSELKNLRLKSRNVKDYKILSNSNQDIIPGINDVENFKELLSALNIIGFSKDQIRWIFQVVAIILLIGNIEF-VSDRAEQASFKND--VSAICSNLGVDEKDFQTAILRPRSKAGKEWVSQSKNSQQAKFILNALSRNLYERLFGYIVDMINKNLDHGSATLN------------------YIGLLDIAGFEIFENNSFEQLCINYTNEKLQQFFNNHMFVLEQSEYLKENIQWDYIDYGKDLQLTIDLIESKGPPTGVLPLLDEEAVLPKSTDESFYSKLISTWDQNSSKFKRSRLKNG-FILKHYAGDVEYTVEGWLSKNKDPLNDNLLSLLSSSQNDIISKLFQ------------PEGEKSSSAGVEANISNQEVKKSARTSTFKTTSSRHREQQITLLNQLASTHPHFVRCIIPNNVKKVKTFNRRLILDQLRCNGVLEGIRLAREGYPNRIAFQEFFQRYRILYPENSTTTTFSSK---LKASTKQNCEFLLTSLQLDTKVYKIGNTKLFFKAGVLADLEKQKDVKLNNIMIKLTATIRGYTVRKE 813
BLAST of Dach-2 vs. Ensembl Yeast
Match: MYO5 (One of two type I myosin motors; contains proline-rich tail homology 2 (TH2) and SH3 domains; MYO5 deletion has little effect on growth, but myo3 myo5 double deletion causes severe defects in growth and actin cytoskeleton organization; MYO5 has a paralog, MYO3, that arose from the whole genome duplication [Source:SGD;Acc:S000004715]) HSP 1 Score: 374.785 bits (961), Expect = 3.087e-108 Identity = 240/754 (31.83%), Postives = 379/754 (50.27%), Query Frame = 2
Query: 245 IGQKDLTYLSYLNEPEVLYNLQIRFCERREIYTYCGIVLVAINPYQELSIYGKEIINAYHSQNSVDLDPHIFAVAENAFRRMSSFGENQSIIVSGESGAGKTVSAKYTMRYFALVGGSKTKQSFNLTETQIERKVLLSNPILEAFGNAKTIRNDNSSRFGKYLEILFNPRNQVIGANMCTYLLEKSRVVFQNLGERNYHIFYQIVTHCQSEDELLMNTGLVNNVEMYDYLRYGESLEIDGVDDSHEFLITKNSFLQLGIDLNKFKTICEILAAILHLGNIRFRFHDATDSSIIENPELLKLIAGLLGCSIDQLKIWLCFRTISTFQ-----ETLHKPLSKAEAQYFRDAFVKTLYSNLFDWIVKQANKVLSTDVSINIKKKLKKTIVVNQEDKKKFIAVLDIYGFETFAENSFEQFCINFANEKLQLQFNLHVFKLEQEEYMNEGLEWTFIDYYNNQPCIDLIESRXXXXX-XXXXXXXXXXXSDENWCCKIYSHHLNKSANFNKPKLSNMVFIIEHFAGPVEYKCAGFIEKNRDSVLEEQINLLKASDVQLIAELFRDSEIEIFDTNNXXXXXXXXXXXXXXXXXXQENTRKMKKTVGSQFRNSLKSLMDALNKTNPHYVRCIKPNDLKLPFTFCPERAVQQLRACGVLETIRLSAAGFPSRWTYSDFYHRYYILMSNFN-VKNHDFKAGSQKIVETLI---TVPDA-FRFGNTKLFFR-PGQVALLEKLRGHKIESSVTLIQSILRGSIERK 2470
+G DLT LS +++ + NL+ RF IYTY G VL+++NP+++L IY ++N Y +N +++ PH+FA+AE+ + M S+ ENQ +I+SGESGAGKT +AK M+Y A + T+ + +I+ VL +NP+LE+FG AKT+RN+NSSR GKYLEI FN + + N+ YLLEK RVV Q ERN+HIFYQ + + T V E Y Y + + +DD ++ T + +G+ + I +LAAIL +GN+ F + ++ + + + +A LL L L R + T H PL+ +A RDA K +Y+NLFDWIV + NK L +K I +LDIYGFE F NSFEQ CIN+ NEKLQ F K EQE Y E ++WT I Y++N+ DLIE+R + +D N + ++ LN L + F+I+H+AG V Y G +KN+D + ++ + L+ + +A +F D+ +++ T G + S L++ L+K P Y+R IKPN+ K P + + + Q++ G+ E +R+ AGF R + F R+Y+L + + ++ ++ + V+ ++ ++P ++ G T +F + P + LE +R + IQ R ++R+
Sbjct: 36 VGVSDLTLLSKISDEAINENLKKRFLNA-TIYTYIGHVLISVNPFRDLGIYTDAVMNEYKGKNRLEVPPHVFAIAESMYYNMKSYNENQCVIISGESGAGKTEAAKRIMQYIAAASSTHTE-----SIGKIKDMVLATNPLLESFGCAKTLRNNNSSRHGKYLEIKFNNQFEPCAGNITNYLLEKQRVVSQIKNERNFHIFYQF---TKGASDAYRQTFGVQKPEQYVYTAAAGCISAETIDDLQDYQETLKAMRVIGLGQEEQDQIFRMLAAILWIGNVSF-IENEEGNAQVRDTSVTDFVAYLLQIDSQLLIKSLVERIMETNHGMKRGSVYHVPLNIVQADAVRDALAKAIYNNLFDWIVSRVNKSLQAFPGA-----------------EKSIGILDIYGFEIFEHNSFEQICINYVNEKLQQIFIQLTLKSEQETYEREKIQWTPIKYFDNKVVCDLIEARRPPGIFAAMNDSVATAHADSNAADQAFAQRLNLFTTNPHFDLRSNKFVIKHYAGDVTYDIDGITDKNKDQLQKDLVELIGTTTNTFLATIFPDT--------------------------VDRESKRRPPTAGDKIIKSANDLVETLSKAQPSYIRTIKPNETKSPNDYDDRQVLHQIKYLGLQENVRIRRAGFAYRQVFEKFVERFYLLSPHCSYAGDYTWQGDTLDAVKYILQDSSIPQQEYQLGVTSVFIKTPETLFALEHMRDRYWHNMAARIQRAWRRFLQRR 736
BLAST of Dach-2 vs. Ensembl Yeast
Match: MYO3 (One of two type I myosins; localizes to actin cortical patches; deletion of MYO3 has little effect on growth, but myo3 myo5 double deletion causes severe defects in growth and actin cytoskeleton organization; MYO3 has a paralog, MYO5, that arose from the whole genome duplication [Source:SGD;Acc:S000001612]) HSP 1 Score: 371.318 bits (952), Expect = 1.011e-106 Identity = 251/794 (31.61%), Postives = 393/794 (49.50%), Query Frame = 2
Query: 209 KCAPFLRNPDILIGQKDLTYLSYLNEPEVLYNLQIRFCERREIYTYCGIVLVAINPYQELSIYGKEIINAYHSQNSVDLDPHIFAVAENAFRRMSSFGENQSIIVSGESGAGKTVSAKYTMRYFALVGGSKTKQSFNLTETQIERKVLLSNPILEAFGNAKTIRNDNSSRFGKYLEILFNPRNQVIGANMCTYLLEKSRVVFQNLGERNYHIFYQIVTHCQSEDELLMNTGLVNNVEMYDYLRYGESLEIDGVDDSHEFLITKNSFLQLGIDLNKFKTICEILAAILHLGNIRFRFHDATDSSIIENPELLKLIAGLLGCSIDQLKIWLCFRTISTFQ-----ETLHKPLSKAEAQYFRDAFVKTLYSNLFDWIVKQANKVLSTDVSINIKKKLKKTIVVNQEDKKKFIAVLDIYGFETFAENSFEQFCINFANEKLQLQFNLHVFKLEQEEYMNEGLEWTFIDYYNNQPCIDLIESRXXXX-XXXXXXXXXXXXSDENWCCKIYSHHLNKSANFNKPKLSNMVFIIEHFAGPVEYKCAGFIEKNRDSVLEEQINLLKASDVQLIAELFRDSEIEIFDTNNXXXXXXXXXXXXXXXXXXQENTRKMKKTVGSQFRNSLKSLMDALNKTNPHYVRCIKPNDLKLPFTFCPERAVQQLRACGVLETIRLSAAGFPSRWTYSDFYHRYYILMSNFN-VKNHDFKAGSQKIVETLI---TVPDA-FRFGNTKLFFR-PGQVALLEKLRGHKIESSVTLIQSILRGSIERKKYLIIHKLTVQIQTYIRRKLAIEKATKL 2554
K A F N +G DLT LS +++ + NL+ RF + IYTY G VL+++NP+++L IY ++ +Y +N +++ PH+FA+AE+ + + S+ ENQ +I+SGESGAGKT +AK M+Y A S ++ + +I+ VL +NP+LE+FG AKT+RN+NSSR GKYLEI FN + + N+ YLLEK RVV Q ERN+HIFYQ + + V E Y Y D +DD ++ T + +G+ + I +LAAIL +GNI F + ++ + + + +A LL L L R + T H PL+ +A RDA K +Y+NLFDWIV + N L + K I +LDIYGFE F NSFEQ CIN+ NEKLQ F K EQE Y E ++WT I Y++N+ DLIE++ + +D N + ++ LN + +L F+I+H+AG V Y G +KN+D + ++ I L+ + ++ +F D +++++ T G + S L++ L+K P Y+R IKPN K P + + + Q++ G+ E +R+ AGF R T+ F R+Y+L + + ++ + + + V+ ++ +P+ F+ G T +F + P + LE +R + IQ R ++R+ ++IQ IR K K KL
Sbjct: 24 KKATFDANKKKEVGISDLTLLSKISDESINENLKKRF-KNGIIYTYIGHVLISVNPFRDLGIYTNAVLESYKGKNRLEVPPHVFAIAESMYYNLKSYNENQCVIISGESGAGKTEAAKRIMQYIAAASNSHSE-----SIGKIKDMVLATNPLLESFGCAKTLRNNNSSRHGKYLEIKFNSQFEPCAGNITNYLLEKQRVVGQIKNERNFHIFYQFTKGASDTYKQMFG---VQMPEQYIYTAAAGCTTADTIDDVKDYEGTLEAMRTIGLVQEEQDQIFRMLAAILWIGNISF-IENEEGNAQVGDTSVTDFVAYLLQVDASLLVKCLVERIMQTSHGMKRGSVYHVPLNPVQATAVRDALAKAIYNNLFDWIVDRVNVSLQAFPGAD-----------------KSIGILDIYGFEIFEHNSFEQICINYVNEKLQQIFIQLTLKAEQETYEREKIKWTPIKYFDNKVVCDLIEAKNPPGILAAMNDSIATAHADSNAADQAFAQRLNLFNSNPYFELRANKFVIKHYAGDVTYDINGITDKNKDQLQKDLIELIGTTTNTFLSTIFPDD--------------------------VDKDSKRRPPTAGDKIIKSANELVETLSKAEPSYIRTIKPNQTKSPNDYDDHQVLHQVKYLGLQENVRIRRAGFAYRQTFEKFVERFYLLSPDCSYAGDYTWDGDTLEAVKLILRDAMIPEKEFQLGVTSVFIKTPESLFALEDMRDKYWYNMAARIQRAWRRFLQRR-----IDAAIKIQRTIREKKGGNKYVKL 759
BLAST of Dach-2 vs. Ensembl Nematostella
Match: EDO41819 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S3A8]) HSP 1 Score: 845.884 bits (2184), Expect = 0.000e+0 Identity = 453/952 (47.58%), Postives = 622/952 (65.34%), Query Frame = 2
Query: 77 VKIWIPDEESVWIGATVLQFHKEKNVIKIITDNGISKELNLSSKKCA-PFLRNPDILIGQKDLTYLSYLNEPEVLYNLQIRFCERREIYTYCGIVLVAINPYQELSIYGKEIINAYHSQNSVDLDPHIFAVAENAFRRMSSFGENQSIIVSGESGAGKTVSAKYTMRYFALVGGSKTKQSFNLTETQIERKVLLSNPILEAFGNAKTIRNDNSSRFGKYLEILFNPRNQVIGANMCTYLLEKSRVVFQNLGERNYHIFYQIVTHCQSEDELLMNTGLVNNVEMYDYLRYGESLEIDGVDDSHEFLITKNSFLQLGIDLNKFKTICEILAAILHLGNIRFRFHDATDSSIIENPELLKLIAGLLGCSIDQLKIWLCFRTISTFQETLHKPLSKAEAQYFRDAFVKTLYSNLFDWIVKQANKVLSTDVSINIKKKLKKTIVVNQEDKKKFIAVLDIYGFETFAENSFEQFCINFANEKLQLQFNLHVFKLEQEEYMNEGLEWTFIDYYNNQPCIDLIESRXXXXXXXXXXXXXXXXSDENWCCKIYSHHLNKSANFNKPKLSNMVFIIEHFAGPVEYKCAGFIEKNRDSVLEEQINLLKASDVQLIAELFRDSEIEIFDTNNXXXXXXXXXXXXXXXXXXQENTRKMKKTVGSQFRNSLKSLMDALNKTNPHYVRCIKPNDLKLPFTFCPERAVQQLRACGVLETIRLSAAGFPSRWTYSDFYHRYYILMSNFNVKNHDFKAGSQKIVETLITVPDAFRFGNTKLFFRPGQVALLEKLRGHKIESSVTLIQSILRGSIERKKYLIIHKLTVQIQTYIRRKLAIEKATKLSQIRAVIIIQSFYRMYLARKLFVKMKCAVLAIEKWRRKIITTRLKQAYKKENCVIICQAIVRRFIQRRKFLKIQRGVILIQNHYRRRKAKETLKILKIEARSINHIKFVNKGLENKIIELTQKLD 2929
++WIP + VWIG + + ++K +++I+ ++G +E+ + ++K P LRNP+IL+G+ DLT LSYL+EP VL+NL +RF + IYTYCGIVLVAINPY+EL +YG +I+ AY ++ D+DPHIFAVAE+AF+ M NQS+IVSGESGAGKTVSAKY MRYF+ VGG+ T ETQIE+KV+ +NPI+EA GNAKTIRNDNSSRFGKYLEI F+ + +IGA+M TYLLEKSRVVFQ ERNYH+FYQ+ C+ + M + + + + YL G++ +D +DD+ F + + +GI+ ++ + IL+AILHLGN+ + ++ EN L++ A LLG +QL+ WLC R I T E L KPLS EA Y R+A K +YS LF W+V N L++ FI VLDIYGFETF NSFEQFCIN+ANEKLQ QF HVFKLEQ+EY+ E ++W+FI++Y+NQPCIDLIE++LG+LDLLDEECK+ KGSD W K+Y HL KS +F+KP++SN+ F+I HFA VEY +GF+EKNRD+V +E + LL+AS+ +++ E+F +++ + + S + KM K+VGSQF SL LM+ LN T PHYVRCIKPND K PF F P+R++QQLRACGVLETIR+SAAG+PSRWTY +F+ RY +L+ + + + + I+ET I D F+ G TK+FFR GQVA LEKLRG K+ S +IQ R E K YL + K + IQ ++R A A L + ++ IQ +YR + R+ +++ A+L I+ + R + R +Q + Q R + R+K+ + +I +Q+ RR +A++ LK LKIEARS+ H K +NKG+ENKIIEL Q+LD
Sbjct: 1 ARVWIPHPDLVWIGGELTKDIEDK-ILEILLEDG--REIIIDTRKSRLPPLRNPEILVGENDLTTLSYLHEPAVLHNLNVRFIQSNAIYTYCGIVLVAINPYEELPLYGPDIVAAYRGRSMGDMDPHIFAVAEDAFQSMIRDERNQSVIVSGESGAGKTVSAKYAMRYFSAVGGAST-------ETQIEKKVIATNPIMEAIGNAKTIRNDNSSRFGKYLEISFDRNHHIIGAHMRTYLLEKSRVVFQAAEERNYHVFYQMCAACELPE---MKDFRLAHPDNFSYLNQGDAPVVDSIDDADCFEELREALSMVGINDDEQLMLFRILSAILHLGNVEILQAGDDECTVEENDFHLEMTAVLLGIDKNQLRKWLCNRKIVTVGEVLIKPLSITEANYGREAISKRIYSQLFKWVVNTINCTLTS-----------------TSKPHSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFTQHVFKLEQDEYVREEIQWSFINFYDNQPCIDLIEAKLGILDLLDEECKMPKGSDSQWAQKLYKQHLQKSKHFSKPRMSNLAFVIHHFADHVEYFVSGFVEKNRDTVNDEHLALLRASEDEMVGEMFTENDAH----------SAPRKRAASRAGKQGGKGGKMFKSVGSQFSVSLSKLMETLNSTTPHYVRCIKPNDTKAPFEFHPKRSIQQLRACGVLETIRISAAGYPSRWTYREFFARYIMLLPSKKINRKKPRETIKLILETFIKDEDMFQMGKTKIFFRAGQVAYLEKLRGDKLRRSCVMIQKNYRCYREHKLYLRMRKAAILIQAWVRGDQARNLARSLRRNKSATTIQRYYRGFHLRQAYLRKHAAILTIQSYARGMSARRQRQVLLYNAKAGVIQRCWRGYKGRQKYRNYFKKIIFLQSCVRRMRARKELKKLKIEARSVEHFKALNKGMENKIIELQQRLD 912
BLAST of Dach-2 vs. Ensembl Nematostella
Match: EDO49515 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RGF6]) HSP 1 Score: 448.358 bits (1152), Expect = 3.878e-134 Identity = 286/814 (35.14%), Postives = 437/814 (53.69%), Query Frame = 2
Query: 236 DILIGQKDLTYLSYLNEPEVLYNLQIRFCERREIYTYCGIVLVAINPYQELSIYGKEIINAYHSQNSVDLDPHIFAVAENAFRRMSSFGENQSIIVSGESGAGKTVSAKYTMRYFALVGGSKTKQSFNLTETQIERKVLLSNPILEAFGNAKTIRNDNSSRFGKYLEILFNPRNQVIGANMCTYLLEKSRVVFQNLGERNYHIFYQIVTHCQSEDELLMNTGLVNNVEMYDYLRYGESLEIDGVDDSHEFLITKNSFLQLGIDLNKFKTICEILAAILHLGNI---RFRFHDATDSSIIENPELLKLIAGLLGCSIDQLKIWLCFRTISTFQETLHKPLSKAEAQYFRDAFVKTLYSNLFDWIVKQANKVLSTDVSINIKKKLKKTIVVNQEDKKKFIAVLDIYGFETFAENSFEQFCINFANEKLQLQFNLHVFKLEQEEYMNEGLEWTFIDYYNNQPCIDLIESRXXXXXXXXXXX--XXXXXSDENWCCKI---YSHHLNKSANFNKPKLSNMV-----FIIEHFAGPVEYKCAGFIEKNRDSVLEEQINLLKASDVQLIAELFRDSEIEIFDTNNXXXXXXXXXXXXXXXXXXQENTRKMKKTVGSQFRNSLKSLMDALNKTNPHYVRCIKPNDLKLPFTFCPERAVQQLRACGVLETIRLSAAGFPSRWTYSDFYHRYYIL----MSNFNVKNHDFKAGSQKIVETLITVPDAFRFGNTKLFFR-PGQVALLEKLRGHKIESSVTLIQSILRGSIERKKYLIIHKLTVQIQTYIRRKLAIEKATKLSQIR-AVIIIQSFYRMYLARKLF 2620
D ++G D+ L L E ++ NL R+ + IYTY G V+V+INPY++ +Y +E+I Y S+N +L PHI+A+A++A+R M ++Q II++GESG+GKT ++K M+Y A V G + +++ ++L SNPILEAFGNAKT+RNDNSSRFGKY++I F+ + +G + YLLEKSR+V+QN GERN+HIFY ++ + D LL + L + + Y YL E + + DD +F + + + +G ++ + ++L+AIL+LGN F D T++ + N ++LK +L C ++ L L RT+ T E +H PL+ A+A Y RDA K +Y LF WIV + N SI ++K+ K+K I VLDIYGFE F +NSFEQF IN+ NEKLQ F K EQEEY+ EG+EWT I+Y+NN +LIE + L +E + + SD + K+ + HH + + +K LS+ F ++H+AG V Y GF++KN D + + + + L +LF + +++++ KT +QF+ S+ LM L NP+Y+RCIKPN+ K F Q+R G++E IR+ AGF R Y RY +L N+ D G ++++ L P + +G TK+F R P + LE+ R +E +IQ I RG +K+Y + + + I Y RR ++R A I+I S+ R + ARK +
Sbjct: 18 DNMVGVSDMVLLEPLTEDAIMENLWDRY-NAKAIYTYIGNVVVSINPYRKFPLYTREVIAEYRSRNIYELPPHIYAIADDAYRSMRDHNKDQCIIITGESGSGKTEASKVIMQYVAAVCGKGREVD------RVKEQLLQSNPILEAFGNAKTLRNDNSSRFGKYMDIEFDFKGDPVGGVITKYLLEKSRLVYQNKGERNFHIFYHLLR--GASDNLLDDLRLTRDFDGYHYLNQSECVSVPTKDDKEDFSVVEKAMEVVGFTEDEISAVYKLLSAILNLGNTELEEFTTSDGTEAVTVLNEQVLKNTCEMLQCDVELLLNSLRERTVETKTERVHTPLNVAQASYARDALAKAVYQRLFAWIVDRVND------SIQVRKR----------GKRKVIGVLDIYGFEIFVDNSFEQFIINYCNEKLQQIFIELTLKSEQEEYVREGIEWTTIEYFNNAVICELIEKNHSGILALLDEECLRPGEVSDLTFLEKLDKQWIHHEHYESRKDKKYLSDKTLPHGYFRLKHYAGKVTYDVDGFLDKNNDLLFRGLSQCMYSCNHPLTKKLFPEG-------------------------CPTKSSKRRPKTTATQFKESVAELMKNLKSKNPNYIRCIKPNERKAAGVFDERLIKHQVRYLGLMENIRVRRAGFAFRQEYPVALQRYKMLCPRTWPNWLGAPRD---GIVELLKHLNVKPTEYAYGRTKIFIRNPRTLFALEEKRKDGMEDLAVIIQKIFRGWRRKKQYQNMRRSEITIAKYYRR---FRDQRDYRRMRNAAILIASYARGWKARKAY 775
BLAST of Dach-2 vs. Ensembl Nematostella
Match: EDO45563 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RSH2]) HSP 1 Score: 434.491 bits (1116), Expect = 2.820e-132 Identity = 300/858 (34.97%), Postives = 451/858 (52.56%), Query Frame = 2
Query: 68 SKGVKIWI---PDEESVWIGATVLQFHKEKNVIKIITDNGISKELNLSSKKCAPFLRN--PDILIGQKDLTYLSYLNEPEVLYNLQIRFCERREIYTYCGIVLVAINPYQELSIYGKEIINAYH-SQNSVDLDPHIFAVAENAFRRMSSFGENQSIIVSGESGAGKTVSAKYTMRYFALVGGSKTKQSFNLTETQIERKVLLSNPILEAFGNAKTIRNDNSSRFGKYLEILFNPRNQVIGANMCTYLLEKSRVVFQNLGERNYHIFYQIVTHCQSEDELLMNTGLVNNVEMYDYLRYGESLEIDGVDDSHEFLITKNSFLQLGIDLNKFKTICEILAAILHLGNIRF--RFHDATDSSIIENPELLKLIAGLLGCSIDQLKIWLCFRTISTFQE--TLHKPLSKAEAQYFRDAFVKTLYSNLFDWIVKQANKVLSTDVSINIKKKLKKTIVVNQEDKKKFIAVLDIYGFETFAENSFEQFCINFANEKLQLQFNLHVFKLEQEEYMNEGLEWTFIDYYNNQPCIDLI-ESRXXXXXXXXXXXXXXXXSDENWCCKI-YSHHLNKSANFNKPKLS-NMVFIIEHFAGPVEYKCAGFIEKNRDSVLEEQINLLKASDVQLIAELFRDSEIEIFDTNNXXXXXXXXXXXXXXXXXXQENTRKMKKTVGSQFRNSLKSLMDALNKTNPHYVRCIKPNDLKLPFTFCPERAVQQLRACGVLETIRLSAAGFPSRWTYSDFYHRYYILMSNFNVKNHDFKAGSQKIVETLITVPDAFRFGNTKLFFRPGQVALLEKLRGHKIESSV-----------------------TLIQSILRGSIERKKYLIIHKLTVQIQTYIR-RKL 2530
++G +W+ E V IGA V KE +I + KE+ + + A L++ P + G +++ L L+E +L NL IR+ +IYTY G VLVA+NPY IYG I+ Y + N+ DL PHI+A E +F M NQ +++SGESGAGKT S K+ ++Y V G + IE ++L +NPILEAFGNAKTIRNDNSSRFGKY+++ FN + GA + YLLE+SR+V Q ERNYHIFY+++ +++ ++ + + + Y YL G L +G+DD++E+ + + + L + + I +AA+LHLGNI F + D ++ + NPE + A LL + ++ F STF E ++ P+S A RDAFVK LYS +F WIV + N +I K K + ++ I VLDI+GFE F NSFEQ CIN+ANE LQ F +FK EQEEY EG+EW F+ + +NQ +D++ E + + L+DEE + +G+DE++ K+ Y+H NK +F +PK F + HFAG V Y GF++KNR++ + ++L+ +S +F TRK T+G QFR SL LM L +VRC+KPN+ K P F E QQLR G+LET+R+ +G+ R T+ +F RY++L+ + ++++ + S I +L+ + ++ G ++F + Q LLE+ R + S + LIQS RG RK +L + + ++Q R RKL
Sbjct: 5 AQGDHVWLEAGDGENDVAIGACV----KEVQGASVILVDDEGKEVVID-RSVAESLKHMHPSSVEGVENMIELGDLDEAGILRNLLIRY-RANKIYTYVGSVLVAVNPYCSFPIYGTAYISRYQKAVNATDLPPHIYATGEMSFAMMKREKHNQCVVISGESGAGKTESTKFILQYLTAVSGR---------HSTIEEQILDANPILEAFGNAKTIRNDNSSRFGKYIDVHFNDSWVIEGAKIDHYLLEQSRIVAQMPNERNYHIFYRMLAGMSPQEKKSLH---LTHAQDYYYLSQGNCLTCEGMDDAYEYDVIRKAMTALWFTEEETQFIFRSIAAVLHLGNISFEAKMEDNIEACDVMNPETVAAAADLLQVPKEHME--EAFTRKSTFAEGEMIYSPVSVERATDIRDAFVKGLYSKVFIWIVNKINS--------SIYKPRGK----DDTSGRQSIGVLDIFGFEKFDMNSFEQLCINYANENLQQFFVAQIFKNEQEEYDREGIEWNFVTFVDNQEVLDMLAEKPMNFIALIDEESRFPQGTDESFLDKLNYNHKDNK--HFVRPKSRVQSQFGVVHFAGTVYYDTTGFLDKNRNTFSADLVDLISSSKCNFFLNMF------------------------FKERSMGTETRKRSPTLGVQFRRSLDVLMKTLASCRSFFVRCVKPNNYKKPMEFDRELCWQQLRYSGMLETVRIRKSGYAMRHTFEEFVTRYHMLVRD-SLRDMSSRDASHLIATSLLG-QENWKLGTKRIFLKESQDVLLEESRAQLLSSKIIFLQRAMRRYLRMRRARRTRKGAVLIQSRWRGYRNRKAFLAMKRGFARLQATFRARKL 802
BLAST of Dach-2 vs. Ensembl Nematostella
Match: EDO45835 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RRW9]) HSP 1 Score: 410.609 bits (1054), Expect = 9.865e-122 Identity = 267/762 (35.04%), Postives = 411/762 (53.94%), Query Frame = 2
Query: 248 GQKDLTYLSYLNEPEVLYNLQIRFCERREIYTYCGIVLVAINPYQELSIYGKEIINAYHSQNSVDLDPHIFAVAENAFRRMSSFGENQSIIVSGESGAGKTVSAKYTMRYFALVGGSKTKQSFNLT-ETQIERK---VLLSNPILEAFGNAKTIRNDNSSRFGKYLEILFNPRNQVIGANMCTYLLEKSRVVFQNLGERNYHIFYQIVTHCQSEDELLMNTGLVNNVEMYDYLRYGESLEIDGVDDSHEFLITKNSFLQLGIDLNKFKTICEILAAILHLGNIRFRFHDATDSSIIENPELLKLIAGLLGCSIDQLKIWLCFRTISTFQETLHKPLSKAEAQYFRDAFVKTLYSNLFDWIVKQANKVLSTDVSINIKKKLKKTIVVNQEDKKKFIAVLDIYGFETFAENSFEQFCINFANEKLQLQFNLHVFKLEQEEYMNEGLEW------TFIDYYNNQPCIDLIES--RXXXXXXXXXXXXXXXXSDE---NWCCKIYSHHLNKSANFNKPKLSNMV----FIIEHFAGPVEYKCAGFIEKNRDSVLEEQINLLKASDVQLIAELFRDSEIEIFDTNNXXXXXXXXXXXXXXXXXXQENTRKMKKTVGSQFRNSLKSLMDALNKTNPHYVRCIKPNDLKLPFTFCPERAVQQLRACGVLETIRLSAAGFPSRWTYSDFYHRYYILMSNF--NVKNHDFKAGSQKIVETLITVPDAFRFGNTKLFFR-PGQVALLEKLRGHKIESSVTLIQSILRGSIER 2467
G+ D L + + + NL+ RF + R IYTY G V+V++NPY+ L IYG + I Y + + PHIFA+A+ ++R M E+ I++SGESG+GKT ++K MRY A + NL+ + +IER +L SN ILE+FGNA+T RNDNSSRFGKY++I F+ + IG ++ YLLEKSRVV Q GERN+H FYQ+ + D ++ GL + +Y Y + G+ +I ++DS + + ++ +G + KT+ +++AAILHLGN+ F H+ + +++EN ++L++IA LLG S + L+ LC+R ++ E + K ++ EA + RDA K Y LF WIV + N SI ++ K + K I VLDIYGFE F NSFEQ CIN+ NEKLQ F V K EQEEY EG+EW + ++Y+NN+ DLIE + + + + + K +D+ K + H + + P +M F I+H+AG V Y F++KN+D++ ++ LL S + + +++ + + I T + T G+ F+NS+ +L++ L P YVRCIKPN++K P F + Q+ G+LE +R+ AG+ R Y F RY + + + D G ++IV++ D ++G TK+F R P + LEK R K+ V ++Q RG I R
Sbjct: 10 GKGDFVLLDEVTKTAFMENLESRFHKER-IYTYIGEVVVSVNPYKTLDIYGDDKIQEYKMREMYERPPHIFALADASYRAMKRRSEDTCIMISGESGSGKTEASKIIMRYIAAIT--------NLSKQKEIERVKDILLKSNAILESFGNARTNRNDNSSRFGKYMDIDFDFKGDPIGGHIFNYLLEKSRVVKQQEGERNFHSFYQVPS-----DSMIGEYGLERDAMLYYYTKQGKVPKISTINDSSLYKLNCDAMKSVGFSAEEQKTVWKLVAAILHLGNVVFT-HEDHEQAVVENKDVLQIIAKLLGLSHEMLERALCYRVVAARGEVMEKGHNEKEAYHGRDALAKAAYDRLFSWIVSRIND------SIEVRDK-------KEHGKCTVIGVLDIYGFEIFETNSFEQLCINYCNEKLQQLFIELVLKEEQEEYQREGIEWKSIHRCSQVEYFNNKIICDLIEQSHKGIIAIMDEGCLNVGKVTDQMLLQTMDKKLAKHPHYRSRLTDPSDKSMEFHRDFCIKHYAGNVIYSVEEFLDKNKDTLFQDFKRLLYNSKHKSLKDMWPEGQESI------------------------TKTTQRPATAGTLFKNSMIALVEKLISKRPFYVRCIKPNEIKSPVAFDEKVVGNQVDYLGLLENVRVRRAGYAFRMHYKRFLLRYKMTDAKTWPSYPGQDID-GVREIVDSH-GFSDDVKYGTTKIFIRTPQTIFELEKSRAAKLPDLVFMLQRCWRGGIAR 717
BLAST of Dach-2 vs. Ensembl Nematostella
Match: EDO35007 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SMP8]) HSP 1 Score: 392.889 bits (1008), Expect = 1.306e-118 Identity = 259/772 (33.55%), Postives = 396/772 (51.30%), Query Frame = 2
Query: 257 DLTYLSYLNEPEVLYNLQIRFCERREIYTYCGIVLVAINPYQELSIYGKEIINAYHSQ--NSVDLDPHIFAVAENAFRRMSSFGENQSIIVSGESGAGKTVSAKYTMRYFALVGGSKTKQSFNLTETQIERK---VLLSNPILEAFGNAKTIRNDNSSRFGKYLEILFNPRNQVIGANMCTYLLEKSRVVFQNLGERNYHIFYQIVTHCQSED--ELLMNTGLVNNVEMYDYLRYGESLEIDGVDDSHEFLITKNSFLQLGIDLNKFKTICEILAAILHLGNIRFRFHD----ATDSSIIENPE-LLKLIAGLLGCSIDQLKIWLCFRTISTFQETLHKPLSKAEAQYFRDAFVKTLYSNLFDWIVKQANKVLSTDVSINIKKKLKKTIVVNQEDKKKFIAVLDIYGFETFAENSFEQFCINFANEKLQLQFNLHVFKLEQEEYMNEGLEWTFIDYYNNQPCIDLIESRXXXXXXXXXXXXXXXXSDENWCCKIYSHHLNKSANFNKPKLSNMV----------------FIIEHFAGPVEYKCAGFIEKNRDSVLEEQINLLKASDVQLIAELFRDSEIEIFDTNNXXXXXXXXXXXXXXXXXXQENTRKMKKTVG-SQFRNSLKSLMDALNKTNPHYVRCIKPNDLKLPFTFCPERAVQQLRACGVLETIRLSAAGFPSRWTYSDFYHRYYILMSNFNVKNH--DFKAGSQKIVETLITVPDAFRFGNTKLFFR-PGQVALLEKLRGHKIESSVTLIQSILRGSIERKKY 2476
D+ + ++E + NL+IR ++ EIYT G VL+++NP+++++IYG + + Y + N PH++ VA N F M G++Q +I+SGESGAGKTVSAK+ M + + V G + T++ER ++ SNP+LEAFGNAKT+ N+NSSRFGK++EI ++ Q G + T+LLEKSRVV Q GERNYHIFYQ+++ C ++ EL ++ G E Y YL I+G DD ++ T N+ +GI + T+ +++A +LHLGNI+F D D S+++ P LL + +L +D+L + E K L+K +A RDA K ++ LF+++V+ N ++T D+ +I VLDIYGFE+F N FEQF IN+ NEKLQ F K+EQEEY EG+ W+ IDY+NN + LIESR + ++ C +++ SAN KL ++ F I H+AG V Y+ GF EKN+D++ + + L+++S + ++F DS + RK K G S+ R +L+ + PHYVRC+KP + K+P + ++ + Q+R G+ E I++ AGF R + RY L+ V+ H D A + I+ ++ G TKLF + P + LE+ R I IQ++ RG RK Y
Sbjct: 7 DMIEIPDVSEASIANNLKIRL-KQEEIYTNIGRVLISVNPFKKINIYGMDAVELYSGKKHNEGAKPPHLYEVANNMFENMLIEGDSQCVIISGESGAGKTVSAKHVMGFLSKVCGEGS--------TEVERVKDIIMQSNPLLEAFGNAKTVMNNNSSRFGKFMEIQYSRSGQPNGGKISTFLLEKSRVVSQGQGERNYHIFYQLLSGCTPDEMSELEIDLG---PAESYKYLNQTGVYTIEGTDDVSDYAATINAMEVIGIASSTRNTVLKLVATVLHLGNIQFTEEDNQAVPVDVSMLDAPSRLLSVDKDIL---LDKLTSYSMETRWGGKVEVTKKTLNKDQAVIARDALAKAIFFQLFEYLVEAVNSTMAT------------------RDQDFYIGVLDIYGFESFKVNGFEQFSINYVNEKLQNLFIDFTLKMEQEEYAEEGISWSDIDYFNNDVVLQLIESRRPPGIMGVL---------DDVCSTLHAVS-EGSANTLMDKLRGVIGSNSSFAKYFQAQARHFAITHYAGKVSYESEGFCEKNKDTLSNDLVCLMQSSTEPFVRDMFPDS---------------------LYGASAGVGGRKAKSNTGSSKIRTQAHALVSKIRMCTPHYVRCVKPTESKIPLDWDDKKVLHQVRYLGLAENIKVRRAGFAFRREFPRIVERYS-LLDPITVRKHQSDPVAACKAILLAGNLDMTKYQVGKTKLFLKEPQMINQLEEARNAIITKYALTIQTVYRGYRARKIY 713
BLAST of Dach-2 vs. Ensembl Medaka
Match: myo5ab (unconventional myosin-Va [Source:NCBI gene;Acc:101173462]) HSP 1 Score: 994.956 bits (2571), Expect = 0.000e+0 Identity = 684/1934 (35.37%), Postives = 1036/1934 (53.57%), Query Frame = 2
Query: 53 LYEMYSKGVKIWIPDEESVWIGATVLQFHKEKNVIKIIT-DNGISKELNLSSKKCA-PFLRNPDILIGQKDLTYLSYLNEPEVLYNLQIRFCERREIYTYCGIVLVAINPYQELSIYGKEIINAYHSQNSVDLDPHIFAVAENAFRRMSSFGENQSIIVSGESGAGKTVSAKYTMRYFALVGGSKTKQSFNLTETQIERKVLLSNPILEAFGNAKTIRNDNSSRFGKYLEILFNPRNQVIGANMCTYLLEKSRVVFQNLGERNYHIFYQIVTHCQSEDELLMNTGLVNNVEMYDYLRYGESLEIDGVDDSHEFLITKNSFLQLGIDLNKFKTICEILAAILHLGNIRFRFHDATDSSIIENPELLKLIAGLLGCSIDQLKIWLCFRTISTFQETLHKPLSKAEAQYFRDAFVKTLYSNLFDWIVKQANKVLSTDVSINIKKKLKKTIVVNQEDKKKFIAVLDIYGFETFAENSFEQFCINFANEKLQLQFNLHVFKLEQEEYMNEGLEWTFIDYYNNQPCIDLIESRXXXXXXXXXXXXXXXXSDENWCCKIYSHHLNKSANFNKPKLSNMVFIIEHFAGPVEYKCAGFIEKNRDSVLEEQINLLKASDVQLIAELFRDSEIEIFDTNNXXXXXXXXXXXXXXXXXXQENTRKMKKTVGSQFRNSLKSLMDALNKTNPHYVRCIKPNDLKLPFTFCPERAVQQLRACGVLETIRLSAAGFPSRWTYSDFYHRYYILMSNFNVKNHDFKAGSQKIVETLITVPDAFRFGNTKLFFRPGQVALLEKLRGHKIESSVTLIQSILRGSIERKKYLIIHKLTVQIQTYIRRKLAIEKATKLSQIRAVIIIQSFYRMYLARKLFVKMKCAVLAIEKWRRKIITTRLKQAYKK---ENCVIICQAIVRRFIQRRKFLKIQRGVILIQNHYRRRKAKETLKILKIEARSINHIKFVNKGLENKIIELTQKLDTKEKE---------MCXXXXXXXXXXXXXXXXXXXXXAESAKIYQNTVQDLQTEIIQLKKELNREIVEKNKIFADKELLEINYKKKINYLENLIEELKSSPSVIEPNIICNGDEAQQSICQDEHQ----------------KFINEQMDHQKLVREYEKLEMKYENLYKEFLFVKSSNQKPSINYD-NQTSNDSE-TES--TFSKDDADVESLSDKVDAKTTKEHXXXXXXXXXXLPNFISESISTAGDLAVVMQLQMNISSLSQENNRLKETVQQFEDELLKYEQCAEDSKGLVIHNEYDNELLSIIKDIKGMDEHGLKSRLIDEVANLKKKLKQSNEDYQK-------------------------------LRLHIFD----------------------GSMSKLTGNLDHESINSEEEELKRAFESQKEANRKMLKEI-EGIKANNVDLKKALFQIRK---DKEQLQVQLGKQHLMIRHGVEYLQNLKLTPKERLDKFVQNEISRILLENLKLQERNDQIISETIELKRGLKYFAFRLQKYEGSLVPNPNKEEDLLQLIQNVIYHSKMKTIGKRECYSEIGLIDLNMSELSIFIKSFIFDLSP-SICLQYEPYHLVPYIIFMVTRKFDFYKEEDQMTNFLSKLIVALKRTIRKRRNYIEYLVMLLSNVFCLVNLXXXXXXXXXXXXLNTAEDIQHYFVHYDLNEFIRLLKELCVTLFQMILKTIVDNLLPQSLCIDAILVHEAIIDFL-SKDGTKYKSNIETQPKNTSFNVLTKNLQSVLEILKNHKIPQLIINQIFVHIAYLINAYCLNTLLFRTDLCYFSKGLQIKYNLSSFETWIRYQKLIDSGALQCLRPMTEAVQLLQTLIDSDEDAKFVCDMCEYLNTRQVVKILNNFNPRDGYGCRLSSGLIAKIETQMKIKRGDEPSESKLETPTVIEIPIDIPFIHNGVSLCRTIIPKPLYLSCLT 5575
L + + ++W+PD +VW A + + + ++ + ++G + E ++ + + P LRNPDIL+G+ DLT LSYL+EP VL+NL++RF + + IYTYCGIVLVAINPY+ L IY +IINAY QN D+DPHIFAVAE A+++M+ NQSII+SGESGAGKTVSAKY MRYFA V S E +E +VL S+PI+EAFGNAKT RNDNSSRFGKY+EI F+ + +IGANM TYLLEKSRVVFQ GERNYHIFYQ+ C S T + + + + G+S IDGV+D+ E T+ +F LG++ I +IL+A+LHL N+ + SSI + + + L+G ++ WLC R + T +E+ KP+ + A RDA K +Y+ LF WIV N L + N FI VLDIYGFETF NSFEQFCIN+ANEKLQ QFNLHVFKL+QEEYM EG+ WT ID+Y+NQPCI+LIE++LG+LDLLDEECK+ KGSD+ W K+Y+ L ++++F KP+LSN FII HFA VEY+C GF+EKN+D+V EEQIN LK + + +LF + + N P + ++ R KKTVG QFR SL LM+ LN T PHYVRCIKPNDLK PF P RAVQQLRACGVLETIR+SAAGFPSRW+Y +F+ RY +LM +V D K + ++E LI + ++FG K+FFR GQVA LEKLR K+ + IQ +R + R+KYL + + IQ Y R A L Q RA + IQ RM+L RK +++ + A +AI+ R + KQ Y K E +I Q VR ++ ++ + + V+L+Q+ RR KAK+ L+ LK+EARS+ H K +N G+ENKI++L QKL+ ++KE + L +E++ + E + TV L ++ L+++L EK+++ + YK++ + ++++L ++++ NI D+ + I Q Q E+ +Q L+ E+ LE ++++L +E + +S+++ D N +SN SE T+S +F +D+ +++ ++ T DL ++++LQ + L QE L + + + E+ + E+ E + V E D E L K ++ +L ++ +L+K L N D LR H+ S + + D ++N E+ EL A+E KE NR + ++ E + ++ +K L ++ K +KEQ Q L Q+L L R++ +++EI+R+ ENL+ E+ ++ +L + LK + +++ +E S V + D ++++ I ++E + G+++ S+LS +K I DL P + + + P L YI+FM R D ++ +++ L+ I ++K ++++ E + L+N L++ +QYSG + F NTA+ + +++L+E+ +L +L + ++ ++K + DN+L Q L + ++L HE I L SK K + T + VL + L L + H + ++ QI Y+I A LN LL R D+C +SKGL I+YN+ E W+ +L DSGA + L P+ +A QLLQ ++ DA +C+MC L T Q++K+L + P + R+S+ I+ I+ +K D + L + PF + V+L IP L L+ LT
Sbjct: 13 LLSCFIQHARVWLPDAATVWQSAELTKDYTPGDLTLCLQLEDGTNVEHKINPQTTSLPPLRNPDILVGENDLTALSYLHEPAVLHNLKVRFIDSKLIYTYCGIVLVAINPYESLPIYEPDIINAYSGQNMGDMDPHIFAVAEEAYKQMARDQRNQSIIISGESGAGKTVSAKYAMRYFATVSCSS-------GEANVEERVLASSPIMEAFGNAKTTRNDNSSRFGKYIEIGFDKKYCIIGANMRTYLLEKSRVVFQAHGERNYHIFYQL---CASSHLPEFKTFKLGCADDFHCTKQGQSPIIDGVNDAKELCSTRRAFSLLGMEEEDQMEIYQILSALLHLSNVEIKDQSGDRSSISPDDVHMMVFCELMGVPCEETAHWLCHRKLKTSKESFVKPVPRVNAVQGRDALAKHIYARLFSWIVGCVNGALKSTGKQN-----------------SFIGVLDIYGFETFDVNSFEQFCINYANEKLQQQFNLHVFKLDQEEYMREGIPWTLIDFYDNQPCINLIEAKLGVLDLLDEECKMPKGSDDTWTQKLYNILLKQNSHFEKPRLSNRAFIIHHFADKVEYQCLGFLEKNKDTVNEEQINALKKTKFDFLLKLFDEDDKGTGSPNKLTPGRAG------------QSQRDNKKTVGLQFRQSLHLLMETLNSTTPHYVRCIKPNDLKAPFVLDPVRAVQQLRACGVLETIRISAAGFPSRWSYPEFFTRYRVLMKQKDVLP-DRKQTCKDLLEKLIKNQEKYQFGKNKIFFRAGQVAYLEKLRSDKLRLACVSIQKTIRCWLARRKYLKTRRSVITIQKYTRGHQARRYVDFLRQTRAAVTIQCNVRMWLERKRYLQKRSAAIAIQSMLRAHMA---KQQYYKLLFEQKAVIIQKWVRGWLAKQHYRRTLAAVVLLQSCVRRIKAKKELRKLKVEARSVEHFKNLNVGMENKIVQLQQKLNEQQKENKEFSERLSVLEKTLTLERERQSREIESLRRSEEETRAKAETVPSLLEQLSFLQQKLETTCREKDELEEQTRI----YKEQT---QQVVDDLNLKNTLLQSNI----DDLNKEIIQQAQQLTETKANFEDTKQLEKDLTEERSRYQSLLSEHLHLEERHKDLKEEMILSNNSSKRGHKRTDSNYSSNSSEFTQSLDSFEGEDSVIQAENEN----------------------------KTTVDLPILLRLQRRVKELEQEKQSLWQQLDKNEEAQQQKEKDIE-KQSTVGRTELDLETL------KRIELESENKKLKQDLTDLRKSLSSENSDAAPPAPGSLPYKTLLEQLTSSIEELEMRKDEVLLLRSHMVRQEALKHRDSILGENAKLELGEIASFQDVNKSTDVHALN-EDGELWLAYEGLKETNRLLECQMQEEQRVHDERYQKLLEEVNKLKAEKEQQQKLLA-------------QSLILPEDARIEASLKHEITRLTNENLERMEQQEKQEKTIRKLTKQLKMYMKKVEDFEAS-VQQASVTTDPVRVV----------NITRKEKEYQ-GMLEYKESDLSRLLKYLIIDLKPRGVAVTFTP-GLPAYIVFMCLRYTDNISDDRRVSTLLNSTISSIKGVVKRKGEDFEVISFWLANTCRLMHCLKQYSGDEAFMVHNTAKQNEQCLTNFELSEYHQLFGDLAIQIYHQLIKCL-DNIL-QPLIVASMLEHEPIQGVLGSKPTGLRKRSTSTSDGAVTIEVLLQRLSVFLTTMSQHGMDVHVVKQIIKQEFYVIGAVTLNHLLLRKDMCSWSKGLHIRYNVWQLEEWLAENELTDSGAKESLEPLIQAAQLLQIKKKTEADALAICNMCTALTTAQIIKVLTLYTPVIDFEERVSTTFISTIKNLLK----DRNDSATLMMDAKKIFSVIFPFTPSSVALETLQIPASLNLAFLT 1824
BLAST of Dach-2 vs. Ensembl Medaka
Match: myo5ab (unconventional myosin-Va [Source:NCBI gene;Acc:101173462]) HSP 1 Score: 987.638 bits (2552), Expect = 0.000e+0 Identity = 671/1882 (35.65%), Postives = 1017/1882 (54.04%), Query Frame = 2
Query: 53 LYEMYSKGVKIWIPDEESVWIGATVLQFHKEKNVIKIIT-DNGISKELNLSSKKCA-PFLRNPDILIGQKDLTYLSYLNEPEVLYNLQIRFCERREIYTYCGIVLVAINPYQELSIYGKEIINAYHSQNSVDLDPHIFAVAENAFRRMSSFGENQSIIVSGESGAGKTVSAKYTMRYFALVGGSKTKQSFNLTETQIERKVLLSNPILEAFGNAKTIRNDNSSRFGKYLEILFNPRNQVIGANMCTYLLEKSRVVFQNLGERNYHIFYQIVTHCQSEDELLMNTGLVNNVEMYDYLRYGESLEIDGVDDSHEFLITKNSFLQLGIDLNKFKTICEILAAILHLGNIRFRFHDATDSSIIENPELLKLIAGLLGCSIDQLKIWLCFRTISTFQETLHKPLSKAEAQYFRDAFVKTLYSNLFDWIVKQANKVLSTDVSINIKKKLKKTIVVNQEDKKKFIAVLDIYGFETFAENSFEQFCINFANEKLQLQFNLHVFKLEQEEYMNEGLEWTFIDYYNNQPCIDLIESRXXXXXXXXXXXXXXXXSDENWCCKIYSHHLNKSANFNKPKLSNMVFIIEHFAGPVEYKCAGFIEKNRDSVLEEQINLLKASDVQLIAELFRDSEIEIFDTNNXXXXXXXXXXXXXXXXXXQENTRKMKKTVGSQFRNSLKSLMDALNKTNPHYVRCIKPNDLKLPFTFCPERAVQQLRACGVLETIRLSAAGFPSRWTYSDFYHRYYILMSNFNVKNHDFKAGSQKIVETLITVPDAFRFGNTKLFFRPGQVALLEKLRGHKIESSVTLIQSILRGSIERKKYLIIHKLTVQIQTYIRRKLAIEKATKLSQIRAVIIIQSFYRMYLARKLFVKMKCAVLAIEKWRRKIITTRLKQAYKK---ENCVIICQAIVRRFIQRRKFLKIQRGVILIQNHYRRRKAKETLKILKIEARSINHIKFVNKGLENKIIELTQKLDTKEKE---------MCXXXXXXXXXXXXXXXXXXXXXAESAKIYQNTVQDLQTEIIQLKKELNREIVEKNKIFADKELLEINYKKKINYLENLIEELKSSPSVIEPNIICNGDEAQQSICQDEHQ----------------KFINEQMDHQKLVREYEKLEMKYENLYKEFLFVKSSNQKPSINYD-NQTSNDSE-TES--TFSKDDADVESLSDKVDAKTTKEHXXXXXXXXXXLPNFISESISTAGDLAVVMQLQMNISSLSQENNRLKETVQQFEDELLKYEQCAEDSKGLVIHNEYDNELLSIIKDIKGMDEHGLKSRLIDEVANLKKKLKQSNEDYQK-------------------------------LRLHIFD----------------------GSMSKLTGNLDHESINSEEEELKRAFESQKEANRKMLKEI-EGIKANNVDLKKALFQIRK---DKEQLQVQLGKQHLMIRHGVEYLQNLKLTPKERLDKFVQNEISRILLENLKLQERNDQIISETIELKRGLKYFAFRLQKYEGSLVPNPNKEEDLLQLIQNVIYHSKMKTIGKRECYSEIGLIDLNMSELSIFIKSFIFDLSP-SICLQYEPYHLVPYIIFMVTRKFDFYKEEDQMTNFLSKLIVALKRTIRKRRNYIEYLVMLLSNVFCLVNLXXXXXXXXXXXXLNTAEDIQHYFVHYDLNEFIRLLKELCVTLFQMILKTIVDNLLPQSLCIDAILVHEAIIDFL-SKDGTKYKSNIETQPKNTSFNVLTKNLQSVLEILKNHKIPQLIINQIFVHIAYLINAYCLNTLLFRTDLCYFSKGLQIKYNLSSFETWIRYQKLIDSGALQCLRPMTEAVQLLQTLIDSDEDAKFVCDMCEYLNTRQVVKILNNFNPRDGYGCRLSSGLIAKIE 5419
L + + ++W+PD +VW A + + + ++ + ++G + E ++ + + P LRNPDIL+G+ DLT LSYL+EP VL+NL++RF + + IYTYCGIVLVAINPY+ L IY +IINAY QN D+DPHIFAVAE A+++M+ NQSII+SGESGAGKTVSAKY MRYFA V S E +E +VL S+PI+EAFGNAKT RNDNSSRFGKY+EI F+ + +IGANM TYLLEKSRVVFQ GERNYHIFYQ+ C S T + + + + G+S IDGV+D+ E T+ +F LG++ I +IL+A+LHL N+ + SSI + + + L+G ++ WLC R + T +E+ KP+ + A RDA K +Y+ LF WIV N L + N FI VLDIYGFETF NSFEQFCIN+ANEKLQ QFNLHVFKL+QEEYM EG+ WT ID+Y+NQPCI+LIE++LG+LDLLDEECK+ KGSD+ W K+Y+ L ++++F KP+LSN FII HFA VEY+C GF+EKN+D+V EEQIN LK + + +LF + + N P + ++ R KKTVG QFR SL LM+ LN T PHYVRCIKPNDLK PF P RAVQQLRACGVLETIR+SAAGFPSRW+Y +F+ RY +LM +V D K + ++E LI + ++FG K+FFR GQVA LEKLR K+ + IQ +R + R+KYL + + IQ Y R A L Q RA + IQ RM+L RK +++ + A +AI+ R + KQ Y K E +I Q VR ++ ++ + + V+L+Q+ RR KAK+ L+ LK+EARS+ H K +N G+ENKI++L QKL+ ++KE + L +E++ + E + TV L ++ L+++L EK+++ + YK++ + ++++L ++++ NI D+ + I Q Q E+ +Q L+ E+ LE ++++L +E + +S+++ D N +SN SE T+S +F +D+ +++ ++ T DL ++++LQ + L QE L + + + E+ + E+ E + V E D E L K ++ +L ++ +L+K L N D LR H+ S + + D ++N E+ EL A+E KE NR + ++ E + ++ +K L ++ K +KEQ Q L Q+L L R++ +++EI+R+ ENL+ E+ ++ +L + LK + +++ +E S V + D ++++ I ++E + G+++ S+LS +K I DL P + + + P L YI+FM R D ++ +++ L+ I ++K ++++ E + L+N L++ +QYSG + F NTA+ + +++L+E+ +L +L + ++ ++K + DN+L Q L + ++L HE I L SK K + T + VL + L L + H + ++ QI Y+I A LN LL R D+C +SKGL I+YN+ E W+ +L DSGA + L P+ +A QLLQ ++ DA +C+MC L T Q++K+L + P + R+S+ I+ I+
Sbjct: 13 LLSCFIQHARVWLPDAATVWQSAELTKDYTPGDLTLCLQLEDGTNVEHKINPQTTSLPPLRNPDILVGENDLTALSYLHEPAVLHNLKVRFIDSKLIYTYCGIVLVAINPYESLPIYEPDIINAYSGQNMGDMDPHIFAVAEEAYKQMARDQRNQSIIISGESGAGKTVSAKYAMRYFATVSCSS-------GEANVEERVLASSPIMEAFGNAKTTRNDNSSRFGKYIEIGFDKKYCIIGANMRTYLLEKSRVVFQAHGERNYHIFYQL---CASSHLPEFKTFKLGCADDFHCTKQGQSPIIDGVNDAKELCSTRRAFSLLGMEEEDQMEIYQILSALLHLSNVEIKDQSGDRSSISPDDVHMMVFCELMGVPCEETAHWLCHRKLKTSKESFVKPVPRVNAVQGRDALAKHIYARLFSWIVGCVNGALKSTGKQN-----------------SFIGVLDIYGFETFDVNSFEQFCINYANEKLQQQFNLHVFKLDQEEYMREGIPWTLIDFYDNQPCINLIEAKLGVLDLLDEECKMPKGSDDTWTQKLYNILLKQNSHFEKPRLSNRAFIIHHFADKVEYQCLGFLEKNKDTVNEEQINALKKTKFDFLLKLFDEDDKGTGSPNKLTPGRAG------------QSQRDNKKTVGLQFRQSLHLLMETLNSTTPHYVRCIKPNDLKAPFVLDPVRAVQQLRACGVLETIRISAAGFPSRWSYPEFFTRYRVLMKQKDVLP-DRKQTCKDLLEKLIKNQEKYQFGKNKIFFRAGQVAYLEKLRSDKLRLACVSIQKTIRCWLARRKYLKTRRSVITIQKYTRGHQARRYVDFLRQTRAAVTIQCNVRMWLERKRYLQKRSAAIAIQSMLRAHMA---KQQYYKLLFEQKAVIIQKWVRGWLAKQHYRRTLAAVVLLQSCVRRIKAKKELRKLKVEARSVEHFKNLNVGMENKIVQLQQKLNEQQKENKEFSERLSVLEKTLTLERERQSREIESLRRSEEETRAKAETVPSLLEQLSFLQQKLETTCREKDELEEQTRI----YKEQT---QQVVDDLNLKNTLLQSNI----DDLNKEIIQQAQQLTETKANFEDTKQLEKDLTEERSRYQSLLSEHLHLEERHKDLKEEMILSNNSSKRGHKRTDSNYSSNSSEFTQSLDSFEGEDSVIQAENEN----------------------------KTTVDLPILLRLQRRVKELEQEKQSLWQQLDKNEEAQQQKEKDIE-KQSTVGRTELDLETL------KRIELESENKKLKQDLTDLRKSLSSENSDAAPPAPGSLPYKTLLEQLTSSIEELEMRKDEVLLLRSHMVRQEALKHRDSILGENAKLELGEIASFQDVNKSTDVHALN-EDGELWLAYEGLKETNRLLECQMQEEQRVHDERYQKLLEEVNKLKAEKEQQQKLLA-------------QSLILPEDARIEASLKHEITRLTNENLERMEQQEKQEKTIRKLTKQLKMYMKKVEDFEAS-VQQASVTTDPVRVV----------NITRKEKEYQ-GMLEYKESDLSRLLKYLIIDLKPRGVAVTFTP-GLPAYIVFMCLRYTDNISDDRRVSTLLNSTISSIKGVVKRKGEDFEVISFWLANTCRLMHCLKQYSGDEAFMVHNTAKQNEQCLTNFELSEYHQLFGDLAIQIYHQLIKCL-DNIL-QPLIVASMLEHEPIQGVLGSKPTGLRKRSTSTSDGAVTIEVLLQRLSVFLTTMSQHGMDVHVVKQIIKQEFYVIGAVTLNHLLLRKDMCSWSKGLHIRYNVWQLEEWLAENELTDSGAKESLEPLIQAAQLLQIKKKTEADALAICNMCTALTTAQIIKVLTLYTPVIDFEERVSTTFISTIK 1776
BLAST of Dach-2 vs. Ensembl Medaka
Match: myo5c (myosin VC [Source:NCBI gene;Acc:101162444]) HSP 1 Score: 651.744 bits (1680), Expect = 0.000e+0 Identity = 370/806 (45.91%), Postives = 498/806 (61.79%), Query Frame = 2
Query: 440 DLDPHIFAVAENAFRRMSSFGENQSIIVSGESGAGKTVSAKYTMRYFALVGGSKTKQSFNLTETQIERKVLLSNPILEAFGNAKTIRNDNSSRFGKYLEILFNPRNQVIGANMCTYLLEKSRVVFQNLGERNYHIFYQIVTHCQSEDELLMNTGLVNNVEMYDYLRYGESLEIDGVDDSHEFLITKNSFLQLGIDLNKFKTICEILAAILHLGNIRFRFHDATDSSIIENPELLKLIAGLLGCSIDQLKIWLCFRTISTFQETLHKPLSKAEAQYFRDAFVKTLYSNLFDWIVKQANKVLSTDVSINIKKKLKKTIVVNQEDKKKFIAVLDIYGFETFAENSFEQFCINFANEKLQLQFNLHVFKLEQEEYMNEGLEWTFIDYYNNQPCIDLIESRXXXXXXXXXXXXXXXXSDENWCCKIYSHHLNKSANFNKPKLSNMVFIIEHFAGPVEYKCAGFIEKNRDSVLEEQINLLKASDVQLIAELFRDSEIEIFDTNNXXXXXXXXXXXXXXXXXXQENTRKMKKTVGSQFRNSLKSLMDALNKTNPHYVRCIKPNDLKLPFTFCPERAVQQLRACGVLETIRLSAAGFPSRWTYSDFYHRYYILMSNFNVKNHDFKAGSQKIVETLITVPDAFRFGNTKLFFRPGQVALLEKLRGHKIESSVTLIQSILRGSIERKKYLIIHKLTVQIQTYIRRKLAIEK---ATKLSQIRAVIIIQSFYRMYLARKLFVKMKCAVLAIEKWRRKIITTRLKQAYKKENCVIICQAIVRRFIQRRKFLKIQRGVILIQNHYR----RRKAKETLK 2836
D+DPHIFAVAE A+++M+ +NQSIIVSGESGAGKTVSA+Y MRYFA+V S K ++E KVL SNPI EA GNAKT RNDNSSRFGKY EI F+ + ++IGANM TYLLEKSRVVFQ ERNYHIFYQ+ C D + + + + + Y G + I+GVDD + T+ +F LG+ + + ++LAAILHLGN+ R SSI L + LL S + L WLC R I ET+ KP+ K A RDA K Y++LFD IV + N L + FI VLDIYGFETF NSFEQFCIN+ANEKLQ QFNLHVFKLEQEEYM E + WT ID+Y+NQP IDLIE++LG++DLLDEEC +G+D++W K+Y ++L+ + F KP+LSN F+I+HFA VEY+C GF+EKNRD++ EE ++ ++AS + +A F++ E+ T N KV + ++++ +VG +FR+SL LM+ LN T PHYVRCIKPND KLPF + R VQQLRACGVLETIR+SA +PSRWTY +FY RY ILMS+ D K + +++ LI + ++FG TK+FFR GQVA LEKLR ++ + +IQ R +R+KYL I + +Q YIR + I K A L Q A ++IQ +R Y R+++ + A + I+ + R + + + + + +I Q R ++ RR+F ++R V+ +Q YR R+K +E K
Sbjct: 3 DMDPHIFAVAEEAYKQMARNHKNQSIIVSGESGAGKTVSARYAMRYFAVVSKSSNK-------NRVEDKVLASNPITEAIGNAKTTRNDNSSRFGKYTEISFDKKYRIIGANMSTYLLEKSRVVFQADDERNYHIFYQM---CSCADLPEFKSLRLLSADKFLYTCMGGDIAIEGVDDKSDMNETRRTFSLLGLKEDFQADVFKVLAAILHLGNVEIRDQGNDKSSIAPTDPHLAVFCELLEVSAEGLLRWLCNRRIVLSAETVVKPVPKERAVAARDALAKQTYAHLFDCIVNRINTALQVPGKPHA-----------------FIGVLDIYGFETFDINSFEQFCINYANEKLQQQFNLHVFKLEQEEYMKEDIPWTLIDFYDNQPVIDLIEAKLGIMDLLDEECLFPQGTDQSWLQKLY-NYLDANPLFEKPRLSNKAFVIQHFADKVEYQCKGFLEKNRDTLYEELVDTMRASKLSFLANFFQEEELT--PTANKSFKVKPARPPV------KATNKQLRTSVGDKFRSSLFLLMETLNATTPHYVRCIKPNDEKLPFEYDSRRVVQQLRACGVLETIRISAQSYPSRWTYIEFYSRYSILMSHLEADVRDKKETCKCVLQRLIHDTNQYKFGRTKIFFRAGQVAYLEKLRLDRLREACVIIQKHFRAWSQRRKYLRIRDAAIVLQQYIRGQKTIRKTVTAEALKQGWAAVVIQRHWRGYCMRQIYQAVCQATITIQAFTRGWMARKQYKKMMEAHKAMILQKYTRAWLARRRFQTMRRLVLNVQLSYRVQQLRKKIEEQTK 772 HSP 2 Score: 156.377 bits (394), Expect = 1.462e-37 Identity = 107/389 (27.51%), Postives = 201/389 (51.67%), Query Frame = 2
Query: 4424 IGLIDLNMSELSIFIKSFIFDLSP-SICLQYEPYHLVPYIIFMVTRKFDFYKEEDQMTNFLSKLIVALKRTIRKRRNYIEYLVMLLSNVFCLVNLXXXXXXXXXXXXLNTAEDIQHYFVHYDLNEFIRLLKELCVTLFQMILKTIVDNLLPQSLCIDAILVHEAIIDFLSKDGTKYK----SNIETQPKNTSFNVLTKNLQSVLEILKNHKIPQLIINQIFVHIAYLINAYCLNTLLFRTDLCYFSKGLQIKYNLSSFETWIRYQKLIDSGALQCLRPMTEAVQLLQTLIDSDEDAKFVCDMCEYLNTRQVVKILNNFNPRDGYGCRLSSGLIAKIETQMKIKRGDEPSESKLETPTVIEIPIDIPFIHNGVSLCRTIIPKPLYLSCLT 5575
+G+++ + S +++ I DL P + + P L YI+FM R D+ ++ ++ + +S +I A+K+ I R L LSN L+NL +QYSG ++F ++ ++ ++DL+E ++ +L + ++ + + L P + +L HE++ S T ++ S + + KN + + + K L + +H + Q +INQ+ + +L+ A LN ++ R D+C KG+QI+ N+S E W++ + L S A++ L P+ +A LLQ +D+DAK + + C LN Q+VKILN++ P D + R++S + K+++ + I G ++L T + PF + +L +P L+L LT
Sbjct: 1227 LGMLEFKREDESRLVQNVILDLQPKGVVVNMIPC-LPAYILFMCVRHADYLNDDAKLKSLMSAIICAVKKVILSRCKDFVLLSFWLSNTHQLINLLKQYSGEEEFLKQSSPRQRKNCLQNFDLSEHRQIFSDLAIHIYHQFISVLQKILTP--AIVPGMLEHESLQGISSMKPTGFRKRSSSLYDEESKNFTISSIIKQLSVFHSTMIHHGMDQNLINQVTKQLFFLVAATTLNQIMLRKDMCSCRKGMQIRCNISYLEEWLKEKDLQSSNAMETLTPLAQAAWLLQVNKSTDDDAKEITEKCTELNPVQIVKILNSYTPIDDFEKRVTSSFVRKVQSLL-IHEGS----TQLMLDTDFHFQVTFPFQSSSQALELLQVPASLHLDFLT 1607
BLAST of Dach-2 vs. Ensembl Medaka
Match: myo5c (myosin VC [Source:NCBI gene;Acc:101162444]) HSP 1 Score: 624.009 bits (1608), Expect = 0.000e+0 Identity = 358/784 (45.66%), Postives = 480/784 (61.22%), Query Frame = 2
Query: 506 NQSIIVSGESGAGKTVSAKYTMRYFALVGGSKTKQSFNLTETQIERKVLLSNPILEAFGNAKTIRNDNSSRFGKYLEILFNPRNQVIGANMCTYLLEKSRVVFQNLGERNYHIFYQIVTHCQSEDELLMNTGLVNNVEMYDYLRYGESLEIDGVDDSHEFLITKNSFLQLGIDLNKFKTICEILAAILHLGNIRFRFHDATDSSIIENPELLKLIAGLLGCSIDQLKIWLCFRTISTFQETLHKPLSKAEAQYFRDAFVKTLYSNLFDWIVKQANKVLSTDVSINIKKKLKKTIVVNQEDKKKFIAVLDIYGFETFAENSFEQFCINFANEKLQLQFNLHVFKLEQEEYMNEGLEWTFIDYYNNQPCIDLIESRXXXXXXXXXXXXXXXXSDENWCCKIYSHHLNKSANFNKPKLSNMVFIIEHFAGPVEYKCAGFIEKNRDSVLEEQINLLKASDVQLIAELFRDSEIEIFDTNNXXXXXXXXXXXXXXXXXXQENTRKMKKTVGSQFRNSLKSLMDALNKTNPHYVRCIKPNDLKLPFTFCPERAVQQLRACGVLETIRLSAAGFPSRWTYSDFYHRYYILMSNFNVKNHDFKAGSQKIVETLITVPDAFRFGNTKLFFRPGQVALLEKLRGHKIESSVTLIQSILRGSIERKKYLIIHKLTVQIQTYIRRKLAIEK---ATKLSQIRAVIIIQSFYRMYLARKLFVKMKCAVLAIEKWRRKIITTRLKQAYKKENCVIICQAIVRRFIQRRKFLKIQRGVILIQNHYR----RRKAKETLK 2836
NQSIIVSGESGAGKTVSA+Y MRYFA+V S K ++E KVL SNPI EA GNAKT RNDNSSRFGKY EI F+ + ++IGANM TYLLEKSRVVFQ ERNYHIFYQ+ C D + + + + + Y G + I+GVDD + T+ +F LG+ + + ++LAAILHLGN+ R SSI L + LL S + L WLC R I ET+ KP+ K A RDA K Y++LFD IV + N L + FI VLDIYGFETF NSFEQFCIN+ANEKLQ QFNLHVFKLEQEEYM E + WT ID+Y+NQP IDLIE++LG++DLLDEEC +G+D++W K+Y ++L+ + F KP+LSN F+I+HFA VEY+C GF+EKNRD++ EE ++ ++AS + +A F++ E+ T N KV + ++++ +VG +FR+SL LM+ LN T PHYVRCIKPND KLPF + R VQQLRACGVLETIR+SA +PSRWTY +FY RY ILMS+ D K + +++ LI + ++FG TK+FFR GQVA LEKLR ++ + +IQ R +R+KYL I + +Q YIR + I K A L Q A ++IQ +R Y R+++ + A + I+ + R + + + + + +I Q R ++ RR+F ++R V+ +Q YR R+K +E K
Sbjct: 9 NQSIIVSGESGAGKTVSARYAMRYFAVVSKSSNK-------NRVEDKVLASNPITEAIGNAKTTRNDNSSRFGKYTEISFDKKYRIIGANMSTYLLEKSRVVFQADDERNYHIFYQM---CSCADLPEFKSLRLLSADKFLYTCMGGDIAIEGVDDKSDMNETRRTFSLLGLKEDFQADVFKVLAAILHLGNVEIRDQGNDKSSIAPTDPHLAVFCELLEVSAEGLLRWLCNRRIVLSAETVVKPVPKERAVAARDALAKQTYAHLFDCIVNRINTALQVPGKPHA-----------------FIGVLDIYGFETFDINSFEQFCINYANEKLQQQFNLHVFKLEQEEYMKEDIPWTLIDFYDNQPVIDLIEAKLGIMDLLDEECLFPQGTDQSWLQKLY-NYLDANPLFEKPRLSNKAFVIQHFADKVEYQCKGFLEKNRDTLYEELVDTMRASKLSFLANFFQEEELT--PTANKSFKVKPARPPV------KATNKQLRTSVGDKFRSSLFLLMETLNATTPHYVRCIKPNDEKLPFEYDSRRVVQQLRACGVLETIRISAQSYPSRWTYIEFYSRYSILMSHLEADVRDKKETCKCVLQRLIHDTNQYKFGRTKIFFRAGQVAYLEKLRLDRLREACVIIQKHFRAWSQRRKYLRIRDAAIVLQQYIRGQKTIRKTVTAEALKQGWAAVVIQRHWRGYCMRQIYQAVCQATITIQAFTRGWMARKQYKKMMEAHKAMILQKYTRAWLARRRFQTMRRLVLNVQLSYRVQQLRKKIEEQTK 756 HSP 2 Score: 156.762 bits (395), Expect = 1.267e-37 Identity = 107/389 (27.51%), Postives = 201/389 (51.67%), Query Frame = 2
Query: 4424 IGLIDLNMSELSIFIKSFIFDLSP-SICLQYEPYHLVPYIIFMVTRKFDFYKEEDQMTNFLSKLIVALKRTIRKRRNYIEYLVMLLSNVFCLVNLXXXXXXXXXXXXLNTAEDIQHYFVHYDLNEFIRLLKELCVTLFQMILKTIVDNLLPQSLCIDAILVHEAIIDFLSKDGTKYK----SNIETQPKNTSFNVLTKNLQSVLEILKNHKIPQLIINQIFVHIAYLINAYCLNTLLFRTDLCYFSKGLQIKYNLSSFETWIRYQKLIDSGALQCLRPMTEAVQLLQTLIDSDEDAKFVCDMCEYLNTRQVVKILNNFNPRDGYGCRLSSGLIAKIETQMKIKRGDEPSESKLETPTVIEIPIDIPFIHNGVSLCRTIIPKPLYLSCLT 5575
+G+++ + S +++ I DL P + + P L YI+FM R D+ ++ ++ + +S +I A+K+ I R L LSN L+NL +QYSG ++F ++ ++ ++DL+E ++ +L + ++ + + L P + +L HE++ S T ++ S + + KN + + + K L + +H + Q +INQ+ + +L+ A LN ++ R D+C KG+QI+ N+S E W++ + L S A++ L P+ +A LLQ +D+DAK + + C LN Q+VKILN++ P D + R++S + K+++ + I G ++L T + PF + +L +P L+L LT
Sbjct: 1211 LGMLEFKREDESRLVQNVILDLQPKGVVVNMIPC-LPAYILFMCVRHADYLNDDAKLKSLMSAIICAVKKVILSRCKDFVLLSFWLSNTHQLINLLKQYSGEEEFLKQSSPRQRKNCLQNFDLSEHRQIFSDLAIHIYHQFISVLQKILTP--AIVPGMLEHESLQGISSMKPTGFRKRSSSLYDEESKNFTISSIIKQLSVFHSTMIHHGMDQNLINQVTKQLFFLVAATTLNQIMLRKDMCSCRKGMQIRCNISYLEEWLKEKDLQSSNAMETLTPLAQAAWLLQVNKSTDDDAKEITEKCTELNPVQIVKILNSYTPIDDFEKRVTSSFVRKVQSLL-IHEGS----TQLMLDTDFHFQVTFPFQSSSQALELLQVPASLHLDFLT 1591
BLAST of Dach-2 vs. Ensembl Medaka
Match: myo5b (myosin VB [Source:ZFIN;Acc:ZDB-GENE-031219-7]) HSP 1 Score: 590.882 bits (1522), Expect = 0.000e+0 Identity = 326/602 (54.15%), Postives = 413/602 (68.60%), Query Frame = 2
Query: 77 VKIWIPDEESVWIGATVLQFHKEKN-VIKIITDNGISKELNLSSKKCA-PFLRNPDILIGQKDLTYLSYLNEPEVLYNLQIRFCERREIYTYCGIVLVAINPYQELSIYGKEIINAYHSQNSVDLDPHIFAVAENAFRRMSSFGENQSIIVSGESGAGKTVSAKYTMRYFALVGGSKTKQSFNLTETQIERKVLLSNPILEAFGNAKTIRNDNSSRFGKYLEILFNPRNQVIGANMCTYLLEKSRVVFQNLGERNYHIFYQIVTHCQSEDELLMNTGLVNNVEMYDYLRYGESLEIDGVDDSHEFLITKNSFLQLGIDLNKFKTICEILAAILHLGNIRFRFHDATDSSIIENPELLKLIAGLLGCSIDQLKIWLCFRTISTFQETLHKPLSKAEAQYFRDAFVKTLYSNLFDWIVKQANKVLSTDVSINIKKKLKKTIVVNQEDKKKFIAVLDIYGFETFAENSFEQFCINFANEKLQLQFNLHVFKLEQEEYMNEGLEWTFIDYYNNQPCIDLIESRXXXXXXXXXXXXXXXXSDENWCCKIYSHHLNKSANFNKPKLSNMVFIIEHFAGPVEYKCAGFIEKNRDSVLEEQINLLKASDV 1876
++WIPD E VW GA +++ +KE + V+ + ++ + E + + PFLRNPDIL+G+ DLT LSYL+EP VL+NL++RF E IYTYCGIVLVAINPY+ L IYG+E+INAY QN D+DPHIFAVAE A+++M+ NQSIIVSGESGAGKTVSAKY MR+FA VGGS T+T +E KVL S+PI+EA GNAKT RNDNSSRFGKY++I F+ +IGANM TYLLEKSRVVFQ ERNYHIFYQ+ + + GL + E + Y GE++ I+GV+D+ +F T+ +F LGI + +I I+A+ILHLGNI+ +S I + LLG + Q++ WLC R + T ET K + +A RDA K +Y+ LFDWIV+ NK L T + FI VLDIYGFETF NSFEQFCIN+ANEKLQ QFN HVFKLEQEEYM E + WT ID+++NQPCIDLIE+RLG+LDLLDEECK+ KG+D+NW K+Y H N SA+F KP++SN+ FI+ HFA VEY+C GF+EKNRD+V EEQIN+LKAS V
Sbjct: 8 TRVWIPDPEEVWKGAEIIKDYKEGDPVLHLKLEDETTLEYQVGPNQNPLPFLRNPDILVGENDLTALSYLHEPAVLHNLRVRFLESNHIYTYCGIVLVAINPYEPLQIYGEEVINAYSGQNMGDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRFFATVGGSS-------TDTSVEEKVLASSPIMEAIGNAKTTRNDNSSRFGKYIQIGFSRHYHIIGANMRTYLLEKSRVVFQAEEERNYHIFYQLCASASLPE--FQDLGLT-SAEDFTYTSLGENIFIEGVNDAEDFCKTREAFTLLGIKDSSQSSIFRIVASILHLGNIQICSERDGESCHILS------FCKLLGVELQQMEHWLCHRKLVTASETYVKSMGAKQAVNARDALAKHIYARLFDWIVEHINKALHTS-----------------SKQHSFIGVLDIYGFETFEVNSFEQFCINYANEKLQQQFNSHVFKLEQEEYMKELIPWTLIDFHDNQPCIDLIEARLGILDLLDEECKVPKGTDQNWAQKLYKQHSN-SAHFQKPRMSNISFIVIHFADKVEYQCDGFLEKNRDTVYEEQINILKASQV 575
BLAST of Dach-2 vs. Planmine SMEST
Match: SMESG000033540.1 (SMESG000033540.1) HSP 1 Score: 3484.12 bits (9033), Expect = 0.000e+0 Identity = 1806/1851 (97.57%), Postives = 1817/1851 (98.16%), Query Frame = 2
Query: 47 MALYEMYSKGVKIWIPDEESVWIGATVLQFHKEKNVIKIITDNGISKELNLSSKKCAPFLRNPDILIGQKDLTYLSYLNEPEVLYNLQIRFCERREIYTYCGIVLVAINPYQELSIYGKEIINAYHSQNSVDLDPHIFAVAENAFRRMSSFGENQSIIVSGESGAGKTVSAKYTMRYFALVGGSKTKQSFNLTETQIERKVLLSNPILEAFGNAKTIRNDNSSRFGKYLEILFNPRNQVIGANMCTYLLEKSRVVFQNLGERNYHIFYQIVTHCQSEDELLMNTGLVNNVEMYDYLRYGESLEIDGVDDSHEFLITKNSFLQLGIDLNKFKTICEILAAILHLGNIRFRFHDATDSSIIENPELLKLIAGLLGCSIDQLKIWLCFRTISTFQETLHKPLSKAEAQYFRDAFVKTLYSNLFDWIVKQANKVLSTDVSINIKKKLKKTIVVNQEDKKKFIAVLDIYGFETFAENSFEQFCINFANEKLQLQFNLHVFKLEQEEYMNEGLEWTFIDYYNNQPCIDLIESRXXXXXXXXXXXXXXXXSDENWCCKIYSHHLNKSANFNKPKLSNMVFIIEHFAGPVEYKCAGFIEKNRDSVLEEQINLLKASDVQLIAELFRDSEIEIFDTNNXXXXXXXXXXXXXXXXXXQENTRKMKKTVGSQFRNSLKSLMDALNKTNPHYVRCIKPNDLKLPFTFCPERAVQQLRACGVLETIRLSAAGFPSRWTYSDFYHRYYILMSNFNVKNHDFKAGSQKIVETLITVPDAFRFGNTKLFFRPGQVALLEKLRGHKIESSVTLIQSILRGSIERKKYLIIHKLTVQIQTYIRRKLAIEKATKLSQIRAVIIIQSFYRMYLARKLFVKMKCAVLAIEKWRRKIITTRLKQAYKKENCVIICQAIVRRFIQRRKFLKIQRGVILIQNHYRRRKAKETLKILKIEARSINHIKFVNKGLENKIIELTQKLDTKEKEMCXXXXXXXXXXXXXXXXXXXXXAESAKIYQNTVQDLQTEIIQLKKELNREIVEKNKIFADKELLEINYKKKINYLENLIEELKSSPSVIEPNIICNGDEAQQSICQDEHQKFINEQMDHQKLVREYEKLEMKYENLYKEFLFVKSSNQKPSINYDNQTSNDSETESTFSKDDADVESLSDKVDAKTTKEHXXXXXXXXXXLPNFISESISTAGDLAVVMQLQMNISSLSQENNRLKETVQQFEDELLKYEQCAEDSKGLVIHNEYDNELLSIIKDIKGMDEHGLKSRLIDEVANLKKKLKQSNEDYQKLRLHIFDGSMSKLTGNLDHESINSEEEELKRAFESQKEANRKMLKEIEGIKANNVDLKKALFQIRKDKEQLQVQLGKQHLMIRHGVEYLQNLKLTPKERLDKFVQNEISRILLENLKLQERNDQIISETIELKRGLKYFAFRLQKYEGSLVPNPNKEEDLLQLIQNVIYHSKMKTIGKRECYSEIGLIDLNMSELSIFIKSFIFDLSPSICLQYEPYHLVPYIIFMVTRKFDFYKEEDQMTNFLSKLIVALKRTIRKRRNYIEYLVMLLSNVFCLVNLXXXXXXXXXXXXLNTAEDIQHYFVHYDLNEFIRLLKELCVTLFQMILKTIVDNLLPQSLCIDAILVHEAIIDFLSKDGTKYKSNIETQPKNTSFNVLTKNLQSVLEILKNHKIPQLIINQIFVHIAYLINAYCLNTLLFRTDLCYFSKGLQIKYNLSSFETWIRYQKLIDSGALQCLRPMTEAVQLLQTLIDSDEDAKFVCDMCEYLNTRQVVKILNNFNPRDGYGCRLSSGLIAKIETQMKIKRGDEPSESKLETPTVIEIPIDIPFIHNGVSLCRTIIPKPLYLSCLTVLSEKDLL 5599
MALYEMYSKGVKIWIPDEESVWIGATVLQFHKEKNVIKIITDNGISKELNLSSK APFLRNPDILIGQKDLTYLSYLNEPEVLYNLQIRFCERREIYTYCGIVLVAINPYQELSIYGKEIINAYHSQNSVDLDPHIFAVAENAFRRMSSFGENQSIIVSGESGAGKTVSAKYTMRYFALVGGSKTKQSFNLTETQIERKVLLSNPILEAFGNAKT+ + I+ + N C L ++ +VVFQNLGERNYHIFYQIVTHCQSEDELLMNTGLVNNVEMYDYLRYGESLEIDGVDDSHEFLITKNSFLQLGIDLNKFKTICEILAAILHLGNIRFR +DATDSSIIENPELLKLIAGLLGCSIDQLKIWLCFRTISTFQETLHKPLSKAEAQYFRDAFVKTLYSNLFDWIVKQANKVLSTDVSINIKKKLKKTIVVNQEDKKKFIAVLDIYGFETFAENSFEQFCINFANEKLQLQFNLHVFKLEQEEYMNEGLEWTFIDYYNNQPCIDLIESRLGLLDLLDEECKLLKGSDENWCCKIYSHHLNKSANFNKPKLS+MVFIIEHFAGPVEYKCAGFIEKNRDSVLEEQINLLKASDVQLIAELFRDSE EI DTNNSKPKVSIKSSTKSIMSIKQENTRKMKKTVGSQFRNSLKSLMDALNKTNPHYVRCIKPNDLKLPFTFCPERAVQQLRACGVLETIRLSAAGFPSRWTYSDFYHRYYILMSNFNVKNHDFKAGSQKIVETLITVPDAFRFGNTKLFFRPGQVALLEKLRGHKIESSVTLIQSILRGSIERK+YLIIHKLTVQIQTYIRRKLAIEKATKLSQIRAVIIIQSFYRMYLARKLFVKMKCAVLAIEKWRRKIITTRLKQAYKKENCVIICQAIVRRFIQRRKFLKIQRGVILIQNHYRRRKAKETLKILKIEARSINHIKFVNKGLENKIIELTQKLDTKEKEMCLIQNQLIKEKKIEILNLKLNQAESAKIYQNTVQDLQTEIIQLKKELNREIVEKNKIFADKELLEINYKKKINYLENLIEELKSSPSVIEPNIICNGDEAQQSICQDEHQKFINEQMDHQKLVREYEKLEMKYENLYKEFLFVKSSNQKPSINYDNQTSNDSETESTFSKDDADVESLSD+VDAKTTKEHVVKSSVVVKKLPNFISESISTAGDLAVVMQLQMNISSLSQENNRLKETVQQFEDELLKYEQ AEDSKGLVIHNEYDNELLSIIKDIKGMDEHGLKSRLIDEVANLKKKLKQSNEDYQKLRLHIFDGSMSKLTGNLDHESINSEEEELKRAFESQKEANRKMLKEIEGIKANNVDLKKALFQIRKDKEQLQVQLGKQHLMIRHGVEYLQNLKLTPKERLDKFVQNEISRILLENLKLQERNDQI SETIELKRGLKYFAFRLQKYEGSLVPNPNKEEDLLQLIQNVIYHSKMKTIGKRECYSEIGLIDLNMSELSIFIKSFIFDLSPSICLQYEPYHLVPYIIFMVTRKFDFYKEEDQMTNFLSKLIVALKRTIRKRRNYIEYLVML SNVFCLVNLFQQYSGSQQFSGLNTAEDIQHYFVHYDLNEFIRLLKELCVTLFQMILKTIVDNLLPQSLCIDAILVHEAIIDFLSKDGTKYKSNIETQPKNTSFNVLTKNLQSVLEILKNHKIPQLIINQIFVHIAYLINAYCLNTLLFRTDLCYFSKGLQIKYNLSSFETWIRYQKLIDSGALQCLRPMTEAVQLLQTLIDSDEDAKFVCDMCEYLNTRQVVKILNNFNPRDGYGCRLSSGLIAKIETQMKIKRGDEPSESKLETPTVIEIPIDIPFIHNGVSLCRTIIPKPLYLSCLTVLSEKDLL
Sbjct: 1 MALYEMYSKGVKIWIPDEESVWIGATVLQFHKEKNVIKIITDNGISKELNLSSKIYAPFLRNPDILIGQKDLTYLSYLNEPEVLYNLQIRFCERREIYTYCGIVLVAINPYQELSIYGKEIINAYHSQNSVDLDPHIFAVAENAFRRMSSFGENQSIIVSGESGAGKTVSAKYTMRYFALVGGSKTKQSFNLTETQIERKVLLSNPILEAFGNAKTLE----------MTIVADLEN---IWKFC--LTQEIKVVFQNLGERNYHIFYQIVTHCQSEDELLMNTGLVNNVEMYDYLRYGESLEIDGVDDSHEFLITKNSFLQLGIDLNKFKTICEILAAILHLGNIRFRSNDATDSSIIENPELLKLIAGLLGCSIDQLKIWLCFRTISTFQETLHKPLSKAEAQYFRDAFVKTLYSNLFDWIVKQANKVLSTDVSINIKKKLKKTIVVNQEDKKKFIAVLDIYGFETFAENSFEQFCINFANEKLQLQFNLHVFKLEQEEYMNEGLEWTFIDYYNNQPCIDLIESRLGLLDLLDEECKLLKGSDENWCCKIYSHHLNKSANFNKPKLSDMVFIIEHFAGPVEYKCAGFIEKNRDSVLEEQINLLKASDVQLIAELFRDSETEILDTNNSKPKVSIKSSTKSIMSIKQENTRKMKKTVGSQFRNSLKSLMDALNKTNPHYVRCIKPNDLKLPFTFCPERAVQQLRACGVLETIRLSAAGFPSRWTYSDFYHRYYILMSNFNVKNHDFKAGSQKIVETLITVPDAFRFGNTKLFFRPGQVALLEKLRGHKIESSVTLIQSILRGSIERKRYLIIHKLTVQIQTYIRRKLAIEKATKLSQIRAVIIIQSFYRMYLARKLFVKMKCAVLAIEKWRRKIITTRLKQAYKKENCVIICQAIVRRFIQRRKFLKIQRGVILIQNHYRRRKAKETLKILKIEARSINHIKFVNKGLENKIIELTQKLDTKEKEMCLIQNQLIKEKKIEILNLKLNQAESAKIYQNTVQDLQTEIIQLKKELNREIVEKNKIFADKELLEINYKKKINYLENLIEELKSSPSVIEPNIICNGDEAQQSICQDEHQKFINEQMDHQKLVREYEKLEMKYENLYKEFLFVKSSNQKPSINYDNQTSNDSETESTFSKDDADVESLSDEVDAKTTKEHVVKSSVVVKKLPNFISESISTAGDLAVVMQLQMNISSLSQENNRLKETVQQFEDELLKYEQGAEDSKGLVIHNEYDNELLSIIKDIKGMDEHGLKSRLIDEVANLKKKLKQSNEDYQKLRLHIFDGSMSKLTGNLDHESINSEEEELKRAFESQKEANRKMLKEIEGIKANNVDLKKALFQIRKDKEQLQVQLGKQHLMIRHGVEYLQNLKLTPKERLDKFVQNEISRILLENLKLQERNDQITSETIELKRGLKYFAFRLQKYEGSLVPNPNKEEDLLQLIQNVIYHSKMKTIGKRECYSEIGLIDLNMSELSIFIKSFIFDLSPSICLQYEPYHLVPYIIFMVTRKFDFYKEEDQMTNFLSKLIVALKRTIRKRRNYIEYLVMLFSNVFCLVNLFQQYSGSQQFSGLNTAEDIQHYFVHYDLNEFIRLLKELCVTLFQMILKTIVDNLLPQSLCIDAILVHEAIIDFLSKDGTKYKSNIETQPKNTSFNVLTKNLQSVLEILKNHKIPQLIINQIFVHIAYLINAYCLNTLLFRTDLCYFSKGLQIKYNLSSFETWIRYQKLIDSGALQCLRPMTEAVQLLQTLIDSDEDAKFVCDMCEYLNTRQVVKILNNFNPRDGYGCRLSSGLIAKIETQMKIKRGDEPSESKLETPTVIEIPIDIPFIHNGVSLCRTIIPKPLYLSCLTVLSEKDLL 1836
BLAST of Dach-2 vs. Planmine SMEST
Match: SMESG000033540.1 (SMESG000033540.1) HSP 1 Score: 3474.49 bits (9008), Expect = 0.000e+0 Identity = 1801/1846 (97.56%), Postives = 1812/1846 (98.16%), Query Frame = 2
Query: 62 MYSKGVKIWIPDEESVWIGATVLQFHKEKNVIKIITDNGISKELNLSSKKCAPFLRNPDILIGQKDLTYLSYLNEPEVLYNLQIRFCERREIYTYCGIVLVAINPYQELSIYGKEIINAYHSQNSVDLDPHIFAVAENAFRRMSSFGENQSIIVSGESGAGKTVSAKYTMRYFALVGGSKTKQSFNLTETQIERKVLLSNPILEAFGNAKTIRNDNSSRFGKYLEILFNPRNQVIGANMCTYLLEKSRVVFQNLGERNYHIFYQIVTHCQSEDELLMNTGLVNNVEMYDYLRYGESLEIDGVDDSHEFLITKNSFLQLGIDLNKFKTICEILAAILHLGNIRFRFHDATDSSIIENPELLKLIAGLLGCSIDQLKIWLCFRTISTFQETLHKPLSKAEAQYFRDAFVKTLYSNLFDWIVKQANKVLSTDVSINIKKKLKKTIVVNQEDKKKFIAVLDIYGFETFAENSFEQFCINFANEKLQLQFNLHVFKLEQEEYMNEGLEWTFIDYYNNQPCIDLIESRXXXXXXXXXXXXXXXXSDENWCCKIYSHHLNKSANFNKPKLSNMVFIIEHFAGPVEYKCAGFIEKNRDSVLEEQINLLKASDVQLIAELFRDSEIEIFDTNNXXXXXXXXXXXXXXXXXXQENTRKMKKTVGSQFRNSLKSLMDALNKTNPHYVRCIKPNDLKLPFTFCPERAVQQLRACGVLETIRLSAAGFPSRWTYSDFYHRYYILMSNFNVKNHDFKAGSQKIVETLITVPDAFRFGNTKLFFRPGQVALLEKLRGHKIESSVTLIQSILRGSIERKKYLIIHKLTVQIQTYIRRKLAIEKATKLSQIRAVIIIQSFYRMYLARKLFVKMKCAVLAIEKWRRKIITTRLKQAYKKENCVIICQAIVRRFIQRRKFLKIQRGVILIQNHYRRRKAKETLKILKIEARSINHIKFVNKGLENKIIELTQKLDTKEKEMCXXXXXXXXXXXXXXXXXXXXXAESAKIYQNTVQDLQTEIIQLKKELNREIVEKNKIFADKELLEINYKKKINYLENLIEELKSSPSVIEPNIICNGDEAQQSICQDEHQKFINEQMDHQKLVREYEKLEMKYENLYKEFLFVKSSNQKPSINYDNQTSNDSETESTFSKDDADVESLSDKVDAKTTKEHXXXXXXXXXXLPNFISESISTAGDLAVVMQLQMNISSLSQENNRLKETVQQFEDELLKYEQCAEDSKGLVIHNEYDNELLSIIKDIKGMDEHGLKSRLIDEVANLKKKLKQSNEDYQKLRLHIFDGSMSKLTGNLDHESINSEEEELKRAFESQKEANRKMLKEIEGIKANNVDLKKALFQIRKDKEQLQVQLGKQHLMIRHGVEYLQNLKLTPKERLDKFVQNEISRILLENLKLQERNDQIISETIELKRGLKYFAFRLQKYEGSLVPNPNKEEDLLQLIQNVIYHSKMKTIGKRECYSEIGLIDLNMSELSIFIKSFIFDLSPSICLQYEPYHLVPYIIFMVTRKFDFYKEEDQMTNFLSKLIVALKRTIRKRRNYIEYLVMLLSNVFCLVNLXXXXXXXXXXXXLNTAEDIQHYFVHYDLNEFIRLLKELCVTLFQMILKTIVDNLLPQSLCIDAILVHEAIIDFLSKDGTKYKSNIETQPKNTSFNVLTKNLQSVLEILKNHKIPQLIINQIFVHIAYLINAYCLNTLLFRTDLCYFSKGLQIKYNLSSFETWIRYQKLIDSGALQCLRPMTEAVQLLQTLIDSDEDAKFVCDMCEYLNTRQVVKILNNFNPRDGYGCRLSSGLIAKIETQMKIKRGDEPSESKLETPTVIEIPIDIPFIHNGVSLCRTIIPKPLYLSCLTVLSEKDLL 5599
MYSKGVKIWIPDEESVWIGATVLQFHKEKNVIKIITDNGISKELNLSSK APFLRNPDILIGQKDLTYLSYLNEPEVLYNLQIRFCERREIYTYCGIVLVAINPYQELSIYGKEIINAYHSQNSVDLDPHIFAVAENAFRRMSSFGENQSIIVSGESGAGKTVSAKYTMRYFALVGGSKTKQSFNLTETQIERKVLLSNPILEAFGNAKT+ + I+ + N C L ++ +VVFQNLGERNYHIFYQIVTHCQSEDELLMNTGLVNNVEMYDYLRYGESLEIDGVDDSHEFLITKNSFLQLGIDLNKFKTICEILAAILHLGNIRFR +DATDSSIIENPELLKLIAGLLGCSIDQLKIWLCFRTISTFQETLHKPLSKAEAQYFRDAFVKTLYSNLFDWIVKQANKVLSTDVSINIKKKLKKTIVVNQEDKKKFIAVLDIYGFETFAENSFEQFCINFANEKLQLQFNLHVFKLEQEEYMNEGLEWTFIDYYNNQPCIDLIESRLGLLDLLDEECKLLKGSDENWCCKIYSHHLNKSANFNKPKLS+MVFIIEHFAGPVEYKCAGFIEKNRDSVLEEQINLLKASDVQLIAELFRDSE EI DTNNSKPKVSIKSSTKSIMSIKQENTRKMKKTVGSQFRNSLKSLMDALNKTNPHYVRCIKPNDLKLPFTFCPERAVQQLRACGVLETIRLSAAGFPSRWTYSDFYHRYYILMSNFNVKNHDFKAGSQKIVETLITVPDAFRFGNTKLFFRPGQVALLEKLRGHKIESSVTLIQSILRGSIERK+YLIIHKLTVQIQTYIRRKLAIEKATKLSQIRAVIIIQSFYRMYLARKLFVKMKCAVLAIEKWRRKIITTRLKQAYKKENCVIICQAIVRRFIQRRKFLKIQRGVILIQNHYRRRKAKETLKILKIEARSINHIKFVNKGLENKIIELTQKLDTKEKEMCLIQNQLIKEKKIEILNLKLNQAESAKIYQNTVQDLQTEIIQLKKELNREIVEKNKIFADKELLEINYKKKINYLENLIEELKSSPSVIEPNIICNGDEAQQSICQDEHQKFINEQMDHQKLVREYEKLEMKYENLYKEFLFVKSSNQKPSINYDNQTSNDSETESTFSKDDADVESLSD+VDAKTTKEHVVKSSVVVKKLPNFISESISTAGDLAVVMQLQMNISSLSQENNRLKETVQQFEDELLKYEQ AEDSKGLVIHNEYDNELLSIIKDIKGMDEHGLKSRLIDEVANLKKKLKQSNEDYQKLRLHIFDGSMSKLTGNLDHESINSEEEELKRAFESQKEANRKMLKEIEGIKANNVDLKKALFQIRKDKEQLQVQLGKQHLMIRHGVEYLQNLKLTPKERLDKFVQNEISRILLENLKLQERNDQI SETIELKRGLKYFAFRLQKYEGSLVPNPNKEEDLLQLIQNVIYHSKMKTIGKRECYSEIGLIDLNMSELSIFIKSFIFDLSPSICLQYEPYHLVPYIIFMVTRKFDFYKEEDQMTNFLSKLIVALKRTIRKRRNYIEYLVML SNVFCLVNLFQQYSGSQQFSGLNTAEDIQHYFVHYDLNEFIRLLKELCVTLFQMILKTIVDNLLPQSLCIDAILVHEAIIDFLSKDGTKYKSNIETQPKNTSFNVLTKNLQSVLEILKNHKIPQLIINQIFVHIAYLINAYCLNTLLFRTDLCYFSKGLQIKYNLSSFETWIRYQKLIDSGALQCLRPMTEAVQLLQTLIDSDEDAKFVCDMCEYLNTRQVVKILNNFNPRDGYGCRLSSGLIAKIETQMKIKRGDEPSESKLETPTVIEIPIDIPFIHNGVSLCRTIIPKPLYLSCLTVLSEKDLL
Sbjct: 1 MYSKGVKIWIPDEESVWIGATVLQFHKEKNVIKIITDNGISKELNLSSKIYAPFLRNPDILIGQKDLTYLSYLNEPEVLYNLQIRFCERREIYTYCGIVLVAINPYQELSIYGKEIINAYHSQNSVDLDPHIFAVAENAFRRMSSFGENQSIIVSGESGAGKTVSAKYTMRYFALVGGSKTKQSFNLTETQIERKVLLSNPILEAFGNAKTLE----------MTIVADLEN---IWKFC--LTQEIKVVFQNLGERNYHIFYQIVTHCQSEDELLMNTGLVNNVEMYDYLRYGESLEIDGVDDSHEFLITKNSFLQLGIDLNKFKTICEILAAILHLGNIRFRSNDATDSSIIENPELLKLIAGLLGCSIDQLKIWLCFRTISTFQETLHKPLSKAEAQYFRDAFVKTLYSNLFDWIVKQANKVLSTDVSINIKKKLKKTIVVNQEDKKKFIAVLDIYGFETFAENSFEQFCINFANEKLQLQFNLHVFKLEQEEYMNEGLEWTFIDYYNNQPCIDLIESRLGLLDLLDEECKLLKGSDENWCCKIYSHHLNKSANFNKPKLSDMVFIIEHFAGPVEYKCAGFIEKNRDSVLEEQINLLKASDVQLIAELFRDSETEILDTNNSKPKVSIKSSTKSIMSIKQENTRKMKKTVGSQFRNSLKSLMDALNKTNPHYVRCIKPNDLKLPFTFCPERAVQQLRACGVLETIRLSAAGFPSRWTYSDFYHRYYILMSNFNVKNHDFKAGSQKIVETLITVPDAFRFGNTKLFFRPGQVALLEKLRGHKIESSVTLIQSILRGSIERKRYLIIHKLTVQIQTYIRRKLAIEKATKLSQIRAVIIIQSFYRMYLARKLFVKMKCAVLAIEKWRRKIITTRLKQAYKKENCVIICQAIVRRFIQRRKFLKIQRGVILIQNHYRRRKAKETLKILKIEARSINHIKFVNKGLENKIIELTQKLDTKEKEMCLIQNQLIKEKKIEILNLKLNQAESAKIYQNTVQDLQTEIIQLKKELNREIVEKNKIFADKELLEINYKKKINYLENLIEELKSSPSVIEPNIICNGDEAQQSICQDEHQKFINEQMDHQKLVREYEKLEMKYENLYKEFLFVKSSNQKPSINYDNQTSNDSETESTFSKDDADVESLSDEVDAKTTKEHVVKSSVVVKKLPNFISESISTAGDLAVVMQLQMNISSLSQENNRLKETVQQFEDELLKYEQGAEDSKGLVIHNEYDNELLSIIKDIKGMDEHGLKSRLIDEVANLKKKLKQSNEDYQKLRLHIFDGSMSKLTGNLDHESINSEEEELKRAFESQKEANRKMLKEIEGIKANNVDLKKALFQIRKDKEQLQVQLGKQHLMIRHGVEYLQNLKLTPKERLDKFVQNEISRILLENLKLQERNDQITSETIELKRGLKYFAFRLQKYEGSLVPNPNKEEDLLQLIQNVIYHSKMKTIGKRECYSEIGLIDLNMSELSIFIKSFIFDLSPSICLQYEPYHLVPYIIFMVTRKFDFYKEEDQMTNFLSKLIVALKRTIRKRRNYIEYLVMLFSNVFCLVNLFQQYSGSQQFSGLNTAEDIQHYFVHYDLNEFIRLLKELCVTLFQMILKTIVDNLLPQSLCIDAILVHEAIIDFLSKDGTKYKSNIETQPKNTSFNVLTKNLQSVLEILKNHKIPQLIINQIFVHIAYLINAYCLNTLLFRTDLCYFSKGLQIKYNLSSFETWIRYQKLIDSGALQCLRPMTEAVQLLQTLIDSDEDAKFVCDMCEYLNTRQVVKILNNFNPRDGYGCRLSSGLIAKIETQMKIKRGDEPSESKLETPTVIEIPIDIPFIHNGVSLCRTIIPKPLYLSCLTVLSEKDLL 1831
BLAST of Dach-2 vs. Planmine SMEST
Match: SMESG000033540.1 (SMESG000033540.1) HSP 1 Score: 3469.09 bits (8994), Expect = 0.000e+0 Identity = 1799/1846 (97.45%), Postives = 1811/1846 (98.10%), Query Frame = 2
Query: 62 MYSKGVKIWIPDEESVWIGATVLQFHKEKNVIKIITDNGISKELNLSSKKCAPFLRNPDILIGQKDLTYLSYLNEPEVLYNLQIRFCERREIYTYCGIVLVAINPYQELSIYGKEIINAYHSQNSVDLDPHIFAVAENAFRRMSSFGENQSIIVSGESGAGKTVSAKYTMRYFALVGGSKTKQSFNLTETQIERKVLLSNPILEAFGNAKTIRNDNSSRFGKYLEILFNPRNQVIGANMCTYLLEKSRVVFQNLGERNYHIFYQIVTHCQSEDELLMNTGLVNNVEMYDYLRYGESLEIDGVDDSHEFLITKNSFLQLGIDLNKFKTICEILAAILHLGNIRFRFHDATDSSIIENPELLKLIAGLLGCSIDQLKIWLCFRTISTFQETLHKPLSKAEAQYFRDAFVKTLYSNLFDWIVKQANKVLSTDVSINIKKKLKKTIVVNQEDKKKFIAVLDIYGFETFAENSFEQFCINFANEKLQLQFNLHVFKLEQEEYMNEGLEWTFIDYYNNQPCIDLIESRXXXXXXXXXXXXXXXXSDENWCCKIYSHHLNKSANFNKPKLSNMVFIIEHFAGPVEYKCAGFIEKNRDSVLEEQINLLKASDVQLIAELFRDSEIEIFDTNNXXXXXXXXXXXXXXXXXXQENTRKMKKTVGSQFRNSLKSLMDALNKTNPHYVRCIKPNDLKLPFTFCPERAVQQLRACGVLETIRLSAAGFPSRWTYSDFYHRYYILMSNFNVKNHDFKAGSQKIVETLITVPDAFRFGNTKLFFRPGQVALLEKLRGHKIESSVTLIQSILRGSIERKKYLIIHKLTVQIQTYIRRKLAIEKATKLSQIRAVIIIQSFYRMYLARKLFVKMKCAVLAIEKWRRKIITTRLKQAYKKENCVIICQAIVRRFIQRRKFLKIQRGVILIQNHYRRRKAKETLKILKIEARSINHIKFVNKGLENKIIELTQKLDTKEKEMCXXXXXXXXXXXXXXXXXXXXXAESAKIYQNTVQDLQTEIIQLKKELNREIVEKNKIFADKELLEINYKKKINYLENLIEELKSSPSVIEPNIICNGDEAQQSICQDEHQKFINEQMDHQKLVREYEKLEMKYENLYKEFLFVKSSNQKPSINYDNQTSNDSETESTFSKDDADVESLSDKVDAKTTKEHXXXXXXXXXXLPNFISESISTAGDLAVVMQLQMNISSLSQENNRLKETVQQFEDELLKYEQCAEDSKGLVIHNEYDNELLSIIKDIKGMDEHGLKSRLIDEVANLKKKLKQSNEDYQKLRLHIFDGSMSKLTGNLDHESINSEEEELKRAFESQKEANRKMLKEIEGIKANNVDLKKALFQIRKDKEQLQVQLGKQHLMIRHGVEYLQNLKLTPKERLDKFVQNEISRILLENLKLQERNDQIISETIELKRGLKYFAFRLQKYEGSLVPNPNKEEDLLQLIQNVIYHSKMKTIGKRECYSEIGLIDLNMSELSIFIKSFIFDLSPSICLQYEPYHLVPYIIFMVTRKFDFYKEEDQMTNFLSKLIVALKRTIRKRRNYIEYLVMLLSNVFCLVNLXXXXXXXXXXXXLNTAEDIQHYFVHYDLNEFIRLLKELCVTLFQMILKTIVDNLLPQSLCIDAILVHEAIIDFLSKDGTKYKSNIETQPKNTSFNVLTKNLQSVLEILKNHKIPQLIINQIFVHIAYLINAYCLNTLLFRTDLCYFSKGLQIKYNLSSFETWIRYQKLIDSGALQCLRPMTEAVQLLQTLIDSDEDAKFVCDMCEYLNTRQVVKILNNFNPRDGYGCRLSSGLIAKIETQMKIKRGDEPSESKLETPTVIEIPIDIPFIHNGVSLCRTIIPKPLYLSCLTVLSEKDLL 5599
+ SKGVKIWIPDEESVWIGATVLQFHKEKNVIKIITDNGISKELNLSSK APFLRNPDILIGQKDLTYLSYLNEPEVLYNLQIRFCERREIYTYCGIVLVAINPYQELSIYGKEIINAYHSQNSVDLDPHIFAVAENAFRRMSSFGENQSIIVSGESGAGKTVSAKYTMRYFALVGGSKTKQSFNLTETQIERKVLLSNPILEAFGNAKT+ + I+ + N C L ++ +VVFQNLGERNYHIFYQIVTHCQSEDELLMNTGLVNNVEMYDYLRYGESLEIDGVDDSHEFLITKNSFLQLGIDLNKFKTICEILAAILHLGNIRFR +DATDSSIIENPELLKLIAGLLGCSIDQLKIWLCFRTISTFQETLHKPLSKAEAQYFRDAFVKTLYSNLFDWIVKQANKVLSTDVSINIKKKLKKTIVVNQEDKKKFIAVLDIYGFETFAENSFEQFCINFANEKLQLQFNLHVFKLEQEEYMNEGLEWTFIDYYNNQPCIDLIESRLGLLDLLDEECKLLKGSDENWCCKIYSHHLNKSANFNKPKLS+MVFIIEHFAGPVEYKCAGFIEKNRDSVLEEQINLLKASDVQLIAELFRDSE EI DTNNSKPKVSIKSSTKSIMSIKQENTRKMKKTVGSQFRNSLKSLMDALNKTNPHYVRCIKPNDLKLPFTFCPERAVQQLRACGVLETIRLSAAGFPSRWTYSDFYHRYYILMSNFNVKNHDFKAGSQKIVETLITVPDAFRFGNTKLFFRPGQVALLEKLRGHKIESSVTLIQSILRGSIERK+YLIIHKLTVQIQTYIRRKLAIEKATKLSQIRAVIIIQSFYRMYLARKLFVKMKCAVLAIEKWRRKIITTRLKQAYKKENCVIICQAIVRRFIQRRKFLKIQRGVILIQNHYRRRKAKETLKILKIEARSINHIKFVNKGLENKIIELTQKLDTKEKEMCLIQNQLIKEKKIEILNLKLNQAESAKIYQNTVQDLQTEIIQLKKELNREIVEKNKIFADKELLEINYKKKINYLENLIEELKSSPSVIEPNIICNGDEAQQSICQDEHQKFINEQMDHQKLVREYEKLEMKYENLYKEFLFVKSSNQKPSINYDNQTSNDSETESTFSKDDADVESLSD+VDAKTTKEHVVKSSVVVKKLPNFISESISTAGDLAVVMQLQMNISSLSQENNRLKETVQQFEDELLKYEQ AEDSKGLVIHNEYDNELLSIIKDIKGMDEHGLKSRLIDEVANLKKKLKQSNEDYQKLRLHIFDGSMSKLTGNLDHESINSEEEELKRAFESQKEANRKMLKEIEGIKANNVDLKKALFQIRKDKEQLQVQLGKQHLMIRHGVEYLQNLKLTPKERLDKFVQNEISRILLENLKLQERNDQI SETIELKRGLKYFAFRLQKYEGSLVPNPNKEEDLLQLIQNVIYHSKMKTIGKRECYSEIGLIDLNMSELSIFIKSFIFDLSPSICLQYEPYHLVPYIIFMVTRKFDFYKEEDQMTNFLSKLIVALKRTIRKRRNYIEYLVML SNVFCLVNLFQQYSGSQQFSGLNTAEDIQHYFVHYDLNEFIRLLKELCVTLFQMILKTIVDNLLPQSLCIDAILVHEAIIDFLSKDGTKYKSNIETQPKNTSFNVLTKNLQSVLEILKNHKIPQLIINQIFVHIAYLINAYCLNTLLFRTDLCYFSKGLQIKYNLSSFETWIRYQKLIDSGALQCLRPMTEAVQLLQTLIDSDEDAKFVCDMCEYLNTRQVVKILNNFNPRDGYGCRLSSGLIAKIETQMKIKRGDEPSESKLETPTVIEIPIDIPFIHNGVSLCRTIIPKPLYLSCLTVLSEKDLL
Sbjct: 5 LSSKGVKIWIPDEESVWIGATVLQFHKEKNVIKIITDNGISKELNLSSKIYAPFLRNPDILIGQKDLTYLSYLNEPEVLYNLQIRFCERREIYTYCGIVLVAINPYQELSIYGKEIINAYHSQNSVDLDPHIFAVAENAFRRMSSFGENQSIIVSGESGAGKTVSAKYTMRYFALVGGSKTKQSFNLTETQIERKVLLSNPILEAFGNAKTLE----------MTIVADLEN---IWKFC--LTQEIKVVFQNLGERNYHIFYQIVTHCQSEDELLMNTGLVNNVEMYDYLRYGESLEIDGVDDSHEFLITKNSFLQLGIDLNKFKTICEILAAILHLGNIRFRSNDATDSSIIENPELLKLIAGLLGCSIDQLKIWLCFRTISTFQETLHKPLSKAEAQYFRDAFVKTLYSNLFDWIVKQANKVLSTDVSINIKKKLKKTIVVNQEDKKKFIAVLDIYGFETFAENSFEQFCINFANEKLQLQFNLHVFKLEQEEYMNEGLEWTFIDYYNNQPCIDLIESRLGLLDLLDEECKLLKGSDENWCCKIYSHHLNKSANFNKPKLSDMVFIIEHFAGPVEYKCAGFIEKNRDSVLEEQINLLKASDVQLIAELFRDSETEILDTNNSKPKVSIKSSTKSIMSIKQENTRKMKKTVGSQFRNSLKSLMDALNKTNPHYVRCIKPNDLKLPFTFCPERAVQQLRACGVLETIRLSAAGFPSRWTYSDFYHRYYILMSNFNVKNHDFKAGSQKIVETLITVPDAFRFGNTKLFFRPGQVALLEKLRGHKIESSVTLIQSILRGSIERKRYLIIHKLTVQIQTYIRRKLAIEKATKLSQIRAVIIIQSFYRMYLARKLFVKMKCAVLAIEKWRRKIITTRLKQAYKKENCVIICQAIVRRFIQRRKFLKIQRGVILIQNHYRRRKAKETLKILKIEARSINHIKFVNKGLENKIIELTQKLDTKEKEMCLIQNQLIKEKKIEILNLKLNQAESAKIYQNTVQDLQTEIIQLKKELNREIVEKNKIFADKELLEINYKKKINYLENLIEELKSSPSVIEPNIICNGDEAQQSICQDEHQKFINEQMDHQKLVREYEKLEMKYENLYKEFLFVKSSNQKPSINYDNQTSNDSETESTFSKDDADVESLSDEVDAKTTKEHVVKSSVVVKKLPNFISESISTAGDLAVVMQLQMNISSLSQENNRLKETVQQFEDELLKYEQGAEDSKGLVIHNEYDNELLSIIKDIKGMDEHGLKSRLIDEVANLKKKLKQSNEDYQKLRLHIFDGSMSKLTGNLDHESINSEEEELKRAFESQKEANRKMLKEIEGIKANNVDLKKALFQIRKDKEQLQVQLGKQHLMIRHGVEYLQNLKLTPKERLDKFVQNEISRILLENLKLQERNDQITSETIELKRGLKYFAFRLQKYEGSLVPNPNKEEDLLQLIQNVIYHSKMKTIGKRECYSEIGLIDLNMSELSIFIKSFIFDLSPSICLQYEPYHLVPYIIFMVTRKFDFYKEEDQMTNFLSKLIVALKRTIRKRRNYIEYLVMLFSNVFCLVNLFQQYSGSQQFSGLNTAEDIQHYFVHYDLNEFIRLLKELCVTLFQMILKTIVDNLLPQSLCIDAILVHEAIIDFLSKDGTKYKSNIETQPKNTSFNVLTKNLQSVLEILKNHKIPQLIINQIFVHIAYLINAYCLNTLLFRTDLCYFSKGLQIKYNLSSFETWIRYQKLIDSGALQCLRPMTEAVQLLQTLIDSDEDAKFVCDMCEYLNTRQVVKILNNFNPRDGYGCRLSSGLIAKIETQMKIKRGDEPSESKLETPTVIEIPIDIPFIHNGVSLCRTIIPKPLYLSCLTVLSEKDLL 1835
BLAST of Dach-2 vs. Planmine SMEST
Match: SMESG000033540.1 (SMESG000033540.1) HSP 1 Score: 3447.14 bits (8937), Expect = 0.000e+0 Identity = 1793/1851 (96.87%), Postives = 1804/1851 (97.46%), Query Frame = 2
Query: 47 MALYEMYSKGVKIWIPDEESVWIGATVLQFHKEKNVIKIITDNGISKELNLSSKKCAPFLRNPDILIGQKDLTYLSYLNEPEVLYNLQIRFCERREIYTYCGIVLVAINPYQELSIYGKEIINAYHSQNSVDLDPHIFAVAENAFRRMSSFGENQSIIVSGESGAGKTVSAKYTMRYFALVGGSKTKQSFNLTETQIERKVLLSNPILEAFGNAKTIRNDNSSRFGKYLEILFNPRNQVIGANMCTYLLEKSRVVFQNLGERNYHIFYQIVTHCQSEDELLMNTGLVNNVEMYDYLRYGESLEIDGVDDSHEFLITKNSFLQLGIDLNKFKTICEILAAILHLGNIRFRFHDATDSSIIENPELLKLIAGLLGCSIDQLKIWLCFRTISTFQETLHKPLSKAEAQYFRDAFVKTLYSNLFDWIVKQANKVLSTDVSINIKKKLKKTIVVNQEDKKKFIAVLDIYGFETFAENSFEQFCINFANEKLQLQFNLHVFKLEQEEYMNEGLEWTFIDYYNNQPCIDLIESRXXXXXXXXXXXXXXXXSDENWCCKIYSHHLNKSANFNKPKLSNMVFIIEHFAGPVEYKCAGFIEKNRDSVLEEQINLLKASDVQLIAELFRDSEIEIFDTNNXXXXXXXXXXXXXXXXXXQENTRKMKKTVGSQFRNSLKSLMDALNKTNPHYVRCIKPNDLKLPFTFCPERAVQQLRACGVLETIRLSAAGFPSRWTYSDFYHRYYILMSNFNVKNHDFKAGSQKIVETLITVPDAFRFGNTKLFFRPGQVALLEKLRGHKIESSVTLIQSILRGSIERKKYLIIHKLTVQIQTYIRRKLAIEKATKLSQIRAVIIIQSFYRMYLARKLFVKMKCAVLAIEKWRRKIITTRLKQAYKKENCVIICQAIVRRFIQRRKFLKIQRGVILIQNHYRRRKAKETLKILKIEARSINHIKFVNKGLENKIIELTQKLDTKEKEMCXXXXXXXXXXXXXXXXXXXXXAESAKIYQNTVQDLQTEIIQLKKELNREIVEKNKIFADKELLEINYKKKINYLENLIEELKSSPSVIEPNIICNGDEAQQSICQDEHQKFINEQMDHQKLVREYEKLEMKYENLYKEFLFVKSSNQKPSINYDNQTSNDSETESTFSKDDADVESLSDKVDAKTTKEHXXXXXXXXXXLPNFISESISTAGDLAVVMQLQMNISSLSQENNRLKETVQQFEDELLKYEQCAEDSKGLVIHNEYDNELLSIIKDIKGMDEHGLKSRLIDEVANLKKKLKQSNEDYQKLRLHIFDGSMSKLTGNLDHESINSEEEELKRAFESQKEANRKMLKEIEGIKANNVDLKKALFQIRKDKEQLQVQLGKQHLMIRHGVEYLQNLKLTPKERLDKFVQNEISRILLENLKLQERNDQIISETIELKRGLKYFAFRLQKYEGSLVPNPNKEEDLLQLIQNVIYHSKMKTIGKRECYSEIGLIDLNMSELSIFIKSFIFDLSPSICLQYEPYHLVPYIIFMVTRKFDFYKEEDQMTNFLSKLIVALKRTIRKRRNYIEYLVMLLSNVFCLVNLXXXXXXXXXXXXLNTAEDIQHYFVHYDLNEFIRLLKELCVTLFQMILKTIVDNLLPQSLCIDAILVHEAIIDFLSKDGTKYKSNIETQPKNTSFNVLTKNLQSVLEILKNHKIPQLIINQIFVHIAYLINAYCLNTLLFRTDLCYFSKGLQIKYNLSSFETWIRYQKLIDSGALQCLRPMTEAVQLLQTLIDSDEDAKFVCDMCEYLNTRQVVKILNNFNPRDGYGCRLSSGLIAKIETQMKIKRGDEPSESKLETPTVIEIPIDIPFIHNGVSLCRTIIPKPLYLSCLTVLSEKDLL 5599
MALYEMYSKGVKIWIPDEESVWIGATVLQFHKEKNVIKIITDNGISKELNLSSK APFLRNPDILIGQKDLTYLSYLNEPEVLYNLQIRFCERREIYTYCGIVLVAINPYQELSIYGKEIINAYHSQNSVDLDPHIFAVAENAFRRMSSFGENQSIIVSGESGAGKTVSAKYTMRYFALVGGSKTKQSFNLTETQIERKVLLSNPILEAFGNAKT+ + I+ + N C L ++ +VVFQNLGERNYHIFYQIVTHCQSEDELLMNTGLVNNVEMYDYLRYGESLEIDGVDDSHEFLITKNSFLQLGIDLNKFKTICEILAAILHLGNIRFR +DATDSSIIENPELLKLIAGLLGCSIDQLKIWLCFRTISTFQETLHKPLSKAEAQYFRDAFVKTLYSNLFDWIVKQANKVLSTDVSINIKKKLKKTIVVNQEDKKKFIAVLDIYGFETFAENSFEQFCINFANEKLQLQFNLHVFKLEQEEYMNEGLEWTFIDYYNNQPCIDLIESRLGLLDLLDEECKLLKGSDENWCCKIYSHHLNKSANFNKPKLS+MVFIIEHFAGPVEYKCAGFIEKNRDSVLEEQINLLKASDVQLIAELFRDSE EI DTNNSKPKVSIKSSTKSIMSIKQENTRKMKKTVGSQFRNSLKSLMDALNKTNPHYVRCIKPNDLKLPFTFCPERAVQQLRACGVLETIRLSAAGFPSRWTYSDFYHRYYILMSNFNVKNHDFKAGSQKIVETLITVPDAFRFGNTKLFFRPGQVALLEKLRGHKIESSVTLIQSILRGSIERK+YLIIHKLTVQIQTYIRRKLAIEKATKLSQIRAVIIIQSFYRMYLARKLFVKMKCAVLAIEKWRRKIITTRLKQAYKKENCVIICQAIVRRFIQRRKFLKIQRGVILIQNHYRRRKAKETLKILKIEARSINHIKFVNKGLENKIIELTQKLDTKEKEMCLIQNQLIKEKKIEILNLKLNQAESAKIYQNTVQDLQTEIIQLKKELNREIVEKNKIFADKELLEINYKKKINYLENLIEELKSSPSVIEPNIICNGDEAQQSICQDEHQKFINEQMDHQKLVREYEKLEMKYENLYKEFLFVKSSNQKPSINYDNQTSNDSETESTFSKDDADVESLSD+VDAKTTKEHVVKSSVVVKKLPNFISESISTAGDLAVVMQLQMNISSLSQENNRLKETVQQFEDELLKYEQ AEDSKGLVIHNEYDNELLSIIKDIKGMDEHGLKSRLIDEVANLKKKLKQSNEDYQKLRLHIFDGSMSKLTGNLDHESINSEEEELKRAFESQKEANRKMLKEIEGIKANNVDLKKALFQIRKDKEQLQVQLGK NLKLTPKERLDKFVQNEISRILLENLKLQERNDQI SETIELKRGLKYFAFRLQKYEGSLVPNPNKEEDLLQLIQNVIYHSKMKTIGKRECYSEIGLIDLNMSELSIFIKSFIFDLSPSICLQYEPYHLVPYIIFMVTRKFDFYKEEDQMTNFLSKLIVALKRTIRKRRNYIEYLVML SNVFCLVNLFQQYSGSQQFSGLNTAEDIQHYFVHYDLNEFIRLLKELCVTLFQMILKTIVDNLLPQSLCIDAILVHEAIIDFLSKDGTKYKSNIETQPKNTSFNVLTKNLQSVLEILKNHKIPQLIINQIFVHIAYLINAYCLNTLLFRTDLCYFSKGLQIKYNLSSFETWIRYQKLIDSGALQCLRPMTEAVQLLQTLIDSDEDAKFVCDMCEYLNTRQVVKILNNFNPRDGYGCRLSSGLIAKIETQMKIKRGDEPSESKLETPTVIEIPIDIPFIHNGVSLCRTIIPKPLYLSCLTVLSEKDLL
Sbjct: 1 MALYEMYSKGVKIWIPDEESVWIGATVLQFHKEKNVIKIITDNGISKELNLSSKIYAPFLRNPDILIGQKDLTYLSYLNEPEVLYNLQIRFCERREIYTYCGIVLVAINPYQELSIYGKEIINAYHSQNSVDLDPHIFAVAENAFRRMSSFGENQSIIVSGESGAGKTVSAKYTMRYFALVGGSKTKQSFNLTETQIERKVLLSNPILEAFGNAKTLE----------MTIVADLEN---IWKFC--LTQEIKVVFQNLGERNYHIFYQIVTHCQSEDELLMNTGLVNNVEMYDYLRYGESLEIDGVDDSHEFLITKNSFLQLGIDLNKFKTICEILAAILHLGNIRFRSNDATDSSIIENPELLKLIAGLLGCSIDQLKIWLCFRTISTFQETLHKPLSKAEAQYFRDAFVKTLYSNLFDWIVKQANKVLSTDVSINIKKKLKKTIVVNQEDKKKFIAVLDIYGFETFAENSFEQFCINFANEKLQLQFNLHVFKLEQEEYMNEGLEWTFIDYYNNQPCIDLIESRLGLLDLLDEECKLLKGSDENWCCKIYSHHLNKSANFNKPKLSDMVFIIEHFAGPVEYKCAGFIEKNRDSVLEEQINLLKASDVQLIAELFRDSETEILDTNNSKPKVSIKSSTKSIMSIKQENTRKMKKTVGSQFRNSLKSLMDALNKTNPHYVRCIKPNDLKLPFTFCPERAVQQLRACGVLETIRLSAAGFPSRWTYSDFYHRYYILMSNFNVKNHDFKAGSQKIVETLITVPDAFRFGNTKLFFRPGQVALLEKLRGHKIESSVTLIQSILRGSIERKRYLIIHKLTVQIQTYIRRKLAIEKATKLSQIRAVIIIQSFYRMYLARKLFVKMKCAVLAIEKWRRKIITTRLKQAYKKENCVIICQAIVRRFIQRRKFLKIQRGVILIQNHYRRRKAKETLKILKIEARSINHIKFVNKGLENKIIELTQKLDTKEKEMCLIQNQLIKEKKIEILNLKLNQAESAKIYQNTVQDLQTEIIQLKKELNREIVEKNKIFADKELLEINYKKKINYLENLIEELKSSPSVIEPNIICNGDEAQQSICQDEHQKFINEQMDHQKLVREYEKLEMKYENLYKEFLFVKSSNQKPSINYDNQTSNDSETESTFSKDDADVESLSDEVDAKTTKEHVVKSSVVVKKLPNFISESISTAGDLAVVMQLQMNISSLSQENNRLKETVQQFEDELLKYEQGAEDSKGLVIHNEYDNELLSIIKDIKGMDEHGLKSRLIDEVANLKKKLKQSNEDYQKLRLHIFDGSMSKLTGNLDHESINSEEEELKRAFESQKEANRKMLKEIEGIKANNVDLKKALFQIRKDKEQLQVQLGK-------------NLKLTPKERLDKFVQNEISRILLENLKLQERNDQITSETIELKRGLKYFAFRLQKYEGSLVPNPNKEEDLLQLIQNVIYHSKMKTIGKRECYSEIGLIDLNMSELSIFIKSFIFDLSPSICLQYEPYHLVPYIIFMVTRKFDFYKEEDQMTNFLSKLIVALKRTIRKRRNYIEYLVMLFSNVFCLVNLFQQYSGSQQFSGLNTAEDIQHYFVHYDLNEFIRLLKELCVTLFQMILKTIVDNLLPQSLCIDAILVHEAIIDFLSKDGTKYKSNIETQPKNTSFNVLTKNLQSVLEILKNHKIPQLIINQIFVHIAYLINAYCLNTLLFRTDLCYFSKGLQIKYNLSSFETWIRYQKLIDSGALQCLRPMTEAVQLLQTLIDSDEDAKFVCDMCEYLNTRQVVKILNNFNPRDGYGCRLSSGLIAKIETQMKIKRGDEPSESKLETPTVIEIPIDIPFIHNGVSLCRTIIPKPLYLSCLTVLSEKDLL 1823
BLAST of Dach-2 vs. Planmine SMEST
Match: SMESG000033540.1 (SMESG000033540.1) HSP 1 Score: 3436.74 bits (8910), Expect = 0.000e+0 Identity = 1788/1846 (96.86%), Postives = 1799/1846 (97.45%), Query Frame = 2
Query: 62 MYSKGVKIWIPDEESVWIGATVLQFHKEKNVIKIITDNGISKELNLSSKKCAPFLRNPDILIGQKDLTYLSYLNEPEVLYNLQIRFCERREIYTYCGIVLVAINPYQELSIYGKEIINAYHSQNSVDLDPHIFAVAENAFRRMSSFGENQSIIVSGESGAGKTVSAKYTMRYFALVGGSKTKQSFNLTETQIERKVLLSNPILEAFGNAKTIRNDNSSRFGKYLEILFNPRNQVIGANMCTYLLEKSRVVFQNLGERNYHIFYQIVTHCQSEDELLMNTGLVNNVEMYDYLRYGESLEIDGVDDSHEFLITKNSFLQLGIDLNKFKTICEILAAILHLGNIRFRFHDATDSSIIENPELLKLIAGLLGCSIDQLKIWLCFRTISTFQETLHKPLSKAEAQYFRDAFVKTLYSNLFDWIVKQANKVLSTDVSINIKKKLKKTIVVNQEDKKKFIAVLDIYGFETFAENSFEQFCINFANEKLQLQFNLHVFKLEQEEYMNEGLEWTFIDYYNNQPCIDLIESRXXXXXXXXXXXXXXXXSDENWCCKIYSHHLNKSANFNKPKLSNMVFIIEHFAGPVEYKCAGFIEKNRDSVLEEQINLLKASDVQLIAELFRDSEIEIFDTNNXXXXXXXXXXXXXXXXXXQENTRKMKKTVGSQFRNSLKSLMDALNKTNPHYVRCIKPNDLKLPFTFCPERAVQQLRACGVLETIRLSAAGFPSRWTYSDFYHRYYILMSNFNVKNHDFKAGSQKIVETLITVPDAFRFGNTKLFFRPGQVALLEKLRGHKIESSVTLIQSILRGSIERKKYLIIHKLTVQIQTYIRRKLAIEKATKLSQIRAVIIIQSFYRMYLARKLFVKMKCAVLAIEKWRRKIITTRLKQAYKKENCVIICQAIVRRFIQRRKFLKIQRGVILIQNHYRRRKAKETLKILKIEARSINHIKFVNKGLENKIIELTQKLDTKEKEMCXXXXXXXXXXXXXXXXXXXXXAESAKIYQNTVQDLQTEIIQLKKELNREIVEKNKIFADKELLEINYKKKINYLENLIEELKSSPSVIEPNIICNGDEAQQSICQDEHQKFINEQMDHQKLVREYEKLEMKYENLYKEFLFVKSSNQKPSINYDNQTSNDSETESTFSKDDADVESLSDKVDAKTTKEHXXXXXXXXXXLPNFISESISTAGDLAVVMQLQMNISSLSQENNRLKETVQQFEDELLKYEQCAEDSKGLVIHNEYDNELLSIIKDIKGMDEHGLKSRLIDEVANLKKKLKQSNEDYQKLRLHIFDGSMSKLTGNLDHESINSEEEELKRAFESQKEANRKMLKEIEGIKANNVDLKKALFQIRKDKEQLQVQLGKQHLMIRHGVEYLQNLKLTPKERLDKFVQNEISRILLENLKLQERNDQIISETIELKRGLKYFAFRLQKYEGSLVPNPNKEEDLLQLIQNVIYHSKMKTIGKRECYSEIGLIDLNMSELSIFIKSFIFDLSPSICLQYEPYHLVPYIIFMVTRKFDFYKEEDQMTNFLSKLIVALKRTIRKRRNYIEYLVMLLSNVFCLVNLXXXXXXXXXXXXLNTAEDIQHYFVHYDLNEFIRLLKELCVTLFQMILKTIVDNLLPQSLCIDAILVHEAIIDFLSKDGTKYKSNIETQPKNTSFNVLTKNLQSVLEILKNHKIPQLIINQIFVHIAYLINAYCLNTLLFRTDLCYFSKGLQIKYNLSSFETWIRYQKLIDSGALQCLRPMTEAVQLLQTLIDSDEDAKFVCDMCEYLNTRQVVKILNNFNPRDGYGCRLSSGLIAKIETQMKIKRGDEPSESKLETPTVIEIPIDIPFIHNGVSLCRTIIPKPLYLSCLTVLSEKDLL 5599
MYSKGVKIWIPDEESVWIGATVLQFHKEKNVIKIITDNGISKELNLSSK APFLRNPDILIGQKDLTYLSYLNEPEVLYNLQIRFCERREIYTYCGIVLVAINPYQELSIYGKEIINAYHSQNSVDLDPHIFAVAENAFRRMSSFGENQSIIVSGESGAGKTVSAKYTMRYFALVGGSKTKQSFNLTETQIERKVLLSNPILEAFGNAKT+ + I+ + N C L ++ +VVFQNLGERNYHIFYQIVTHCQSEDELLMNTGLVNNVEMYDYLRYGESLEIDGVDDSHEFLITKNSFLQLGIDLNKFKTICEILAAILHLGNIRFR +DATDSSIIENPELLKLIAGLLGCSIDQLKIWLCFRTISTFQETLHKPLSKAEAQYFRDAFVKTLYSNLFDWIVKQANKVLSTDVSINIKKKLKKTIVVNQEDKKKFIAVLDIYGFETFAENSFEQFCINFANEKLQLQFNLHVFKLEQEEYMNEGLEWTFIDYYNNQPCIDLIESRLGLLDLLDEECKLLKGSDENWCCKIYSHHLNKSANFNKPKLS+MVFIIEHFAGPVEYKCAGFIEKNRDSVLEEQINLLKASDVQLIAELFRDSE EI DTNNSKPKVSIKSSTKSIMSIKQENTRKMKKTVGSQFRNSLKSLMDALNKTNPHYVRCIKPNDLKLPFTFCPERAVQQLRACGVLETIRLSAAGFPSRWTYSDFYHRYYILMSNFNVKNHDFKAGSQKIVETLITVPDAFRFGNTKLFFRPGQVALLEKLRGHKIESSVTLIQSILRGSIERK+YLIIHKLTVQIQTYIRRKLAIEKATKLSQIRAVIIIQSFYRMYLARKLFVKMKCAVLAIEKWRRKIITTRLKQAYKKENCVIICQAIVRRFIQRRKFLKIQRGVILIQNHYRRRKAKETLKILKIEARSINHIKFVNKGLENKIIELTQKLDTKEKEMCLIQNQLIKEKKIEILNLKLNQAESAKIYQNTVQDLQTEIIQLKKELNREIVEKNKIFADKELLEINYKKKINYLENLIEELKSSPSVIEPNIICNGDEAQQSICQDEHQKFINEQMDHQKLVREYEKLEMKYENLYKEFLFVKSSNQKPSINYDNQTSNDSETESTFSKDDADVESLSD+VDAKTTKEHVVKSSVVVKKLPNFISESISTAGDLAVVMQLQMNISSLSQENNRLKETVQQFEDELLKYEQ AEDSKGLVIHNEYDNELLSIIKDIKGMDEHGLKSRLIDEVANLKKKLKQSNEDYQKLRLHIFDGSMSKLTGNLDHESINSEEEELKRAFESQKEANRKMLKEIEGIKANNVDLKKALFQIRKDKEQLQVQLGK NLKLTPKERLDKFVQNEISRILLENLKLQERNDQI SETIELKRGLKYFAFRLQKYEGSLVPNPNKEEDLLQLIQNVIYHSKMKTIGKRECYSEIGLIDLNMSELSIFIKSFIFDLSPSICLQYEPYHLVPYIIFMVTRKFDFYKEEDQMTNFLSKLIVALKRTIRKRRNYIEYLVML SNVFCLVNLFQQYSGSQQFSGLNTAEDIQHYFVHYDLNEFIRLLKELCVTLFQMILKTIVDNLLPQSLCIDAILVHEAIIDFLSKDGTKYKSNIETQPKNTSFNVLTKNLQSVLEILKNHKIPQLIINQIFVHIAYLINAYCLNTLLFRTDLCYFSKGLQIKYNLSSFETWIRYQKLIDSGALQCLRPMTEAVQLLQTLIDSDEDAKFVCDMCEYLNTRQVVKILNNFNPRDGYGCRLSSGLIAKIETQMKIKRGDEPSESKLETPTVIEIPIDIPFIHNGVSLCRTIIPKPLYLSCLTVLSEKDLL
Sbjct: 1 MYSKGVKIWIPDEESVWIGATVLQFHKEKNVIKIITDNGISKELNLSSKIYAPFLRNPDILIGQKDLTYLSYLNEPEVLYNLQIRFCERREIYTYCGIVLVAINPYQELSIYGKEIINAYHSQNSVDLDPHIFAVAENAFRRMSSFGENQSIIVSGESGAGKTVSAKYTMRYFALVGGSKTKQSFNLTETQIERKVLLSNPILEAFGNAKTLE----------MTIVADLEN---IWKFC--LTQEIKVVFQNLGERNYHIFYQIVTHCQSEDELLMNTGLVNNVEMYDYLRYGESLEIDGVDDSHEFLITKNSFLQLGIDLNKFKTICEILAAILHLGNIRFRSNDATDSSIIENPELLKLIAGLLGCSIDQLKIWLCFRTISTFQETLHKPLSKAEAQYFRDAFVKTLYSNLFDWIVKQANKVLSTDVSINIKKKLKKTIVVNQEDKKKFIAVLDIYGFETFAENSFEQFCINFANEKLQLQFNLHVFKLEQEEYMNEGLEWTFIDYYNNQPCIDLIESRLGLLDLLDEECKLLKGSDENWCCKIYSHHLNKSANFNKPKLSDMVFIIEHFAGPVEYKCAGFIEKNRDSVLEEQINLLKASDVQLIAELFRDSETEILDTNNSKPKVSIKSSTKSIMSIKQENTRKMKKTVGSQFRNSLKSLMDALNKTNPHYVRCIKPNDLKLPFTFCPERAVQQLRACGVLETIRLSAAGFPSRWTYSDFYHRYYILMSNFNVKNHDFKAGSQKIVETLITVPDAFRFGNTKLFFRPGQVALLEKLRGHKIESSVTLIQSILRGSIERKRYLIIHKLTVQIQTYIRRKLAIEKATKLSQIRAVIIIQSFYRMYLARKLFVKMKCAVLAIEKWRRKIITTRLKQAYKKENCVIICQAIVRRFIQRRKFLKIQRGVILIQNHYRRRKAKETLKILKIEARSINHIKFVNKGLENKIIELTQKLDTKEKEMCLIQNQLIKEKKIEILNLKLNQAESAKIYQNTVQDLQTEIIQLKKELNREIVEKNKIFADKELLEINYKKKINYLENLIEELKSSPSVIEPNIICNGDEAQQSICQDEHQKFINEQMDHQKLVREYEKLEMKYENLYKEFLFVKSSNQKPSINYDNQTSNDSETESTFSKDDADVESLSDEVDAKTTKEHVVKSSVVVKKLPNFISESISTAGDLAVVMQLQMNISSLSQENNRLKETVQQFEDELLKYEQGAEDSKGLVIHNEYDNELLSIIKDIKGMDEHGLKSRLIDEVANLKKKLKQSNEDYQKLRLHIFDGSMSKLTGNLDHESINSEEEELKRAFESQKEANRKMLKEIEGIKANNVDLKKALFQIRKDKEQLQVQLGK-------------NLKLTPKERLDKFVQNEISRILLENLKLQERNDQITSETIELKRGLKYFAFRLQKYEGSLVPNPNKEEDLLQLIQNVIYHSKMKTIGKRECYSEIGLIDLNMSELSIFIKSFIFDLSPSICLQYEPYHLVPYIIFMVTRKFDFYKEEDQMTNFLSKLIVALKRTIRKRRNYIEYLVMLFSNVFCLVNLFQQYSGSQQFSGLNTAEDIQHYFVHYDLNEFIRLLKELCVTLFQMILKTIVDNLLPQSLCIDAILVHEAIIDFLSKDGTKYKSNIETQPKNTSFNVLTKNLQSVLEILKNHKIPQLIINQIFVHIAYLINAYCLNTLLFRTDLCYFSKGLQIKYNLSSFETWIRYQKLIDSGALQCLRPMTEAVQLLQTLIDSDEDAKFVCDMCEYLNTRQVVKILNNFNPRDGYGCRLSSGLIAKIETQMKIKRGDEPSESKLETPTVIEIPIDIPFIHNGVSLCRTIIPKPLYLSCLTVLSEKDLL 1818 The following BLAST results are available for this feature:
BLAST of Dach-2 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Dach-2 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Dach-2 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Dach-2 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Dach-2 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Dach-2 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Dach-2 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Dach-2 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Dach-2 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Dach-2 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of Dach-2 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 5
BLAST of Dach-2 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Dach-2 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Dach-2 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30009793 ID=SMED30009793|Name=Dach-2|organism=Schmidtea mediterranea sexual|type=transcript|length=5875bpback to top protein sequence of SMED30009793-orf-1 >SMED30009793-orf-1 ID=SMED30009793-orf-1|Name=SMED30009793-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=1852bp MALYEMYSKGVKIWIPDEESVWIGATVLQFHKEKNVIKIITDNGISKELNback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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