TBC1 domain family member 17
|
Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30009767 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 4
Homology
BLAST of TBC1 domain family member 17 vs. Ensembl Human
Match: TBC1D15 (TBC1 domain family member 15 [Source:HGNC Symbol;Acc:HGNC:25694]) HSP 1 Score: 357.836 bits (917), Expect = 4.831e-114 Identity = 191/495 (38.59%), Postives = 300/495 (60.61%), Query Frame = 1
Query: 217 LEDLKSFKRSKMTVGNFNSYMIFFMKDGTSHPMMVFRDGGTKNLMDKLENYLSITKSNKERSLFLTELRREDAVFQSFESLGMFSNTKEIQASKYSQPVSNTKEKIWSGLANIGAITNQFIRSI-PNDQYSHIRDLLR-EDAFGIPIEGHRLNTREDQESGFEIISKPVRIELPHPSPIQRRPPLTESEWKKHLSPDGTVTCVEQLMEKIFKGGIEMSLRSTVWKYLLNFYKWDYSLEKNHEMSRRKNDIYHKLKFQWRSIFMEQEDRFTPFRERKSIIEKDMLRTDRALEFYSDEQG-NLQLIYNILMSYSMYNFDLGYVQGMNDILAPILFLINDEVDAFWCFTNLMDTLEPNFTQEQLGIKKQFRQLYTLVQIFDPEFAEYLDANGCKEMLFCFRWLLVKFKRELSYENTMLLWEVLWTNYRCINFHLIFALSVLLHEKNHIMENKYGFNEILKHVNDLKLNDDLENHLCRAESLYLQ------LDQIWCQI 1674
L DLKS K++K +G SY++F +KD P + F G +K L++ LE Y+ + +S +++ L + + ++ QSFE+L + Y K+ + + +TN S+ +D +H R D I G ++N +E E GFE+I+ RI+L +QRR P++ EW K++ +G + V+ + + IF+GG+ +LR WK+LL ++ WD + E+ ++ ++K D Y ++K QW+SI EQE R + R+ +S+IEKD+ RTDR +FY + L L+++ILM+Y MY+FDLGYVQGM+D+L+P+L+++ +EVDAFWCF + MD + NF ++ G+K Q QL TL+++ D F YL++ + FCFRWLL++FKRE S+ + + LWEV+WT C NFHL+ ++L EK IME YGFNEILKH+N+L + D+E+ LC+AE++ LQ L Q C+I
Sbjct: 132 LTDLKSIKQNKEGMGW--SYLVFCLKDDVVLPALHFHQGDSKLLIESLEKYVVLCESPQDKRTLLVNCQNK-SLSQSFENL--------LDEPAYGLIQKIKKDPYTATMIGFSKVTNYIFDSLRGSDPSTHQRPPSEMADFLSDAIPGLKINQQE--EPGFEVIT---RIDLGERPVVQRREPVSLEEWTKNIDSEGRILNVDNMKQMIFRGGLSHALRKQAWKFLLGYFPWDSTKEERTQLQKQKTDEYFRMKLQWKSISQEQEKRNSRLRDYRSLIEKDVNRTDRTNKFYEGQDNPGLILLHDILMTYCMYDFDLGYVQGMSDLLSPLLYVMENEVDAFWCFASYMDQMHQNFEEQMQGMKTQLIQLSTLLRLLDSGFCSYLESQDSGYLYFCFRWLLIRFKREFSFLDILRLWEVMWTELPCTNFHLLLCCAILESEKQQIMEKHYGFNEILKHINELSMKIDVEDILCKAEAISLQMVKCKELPQAVCEI 610
BLAST of TBC1 domain family member 17 vs. Ensembl Human
Match: TBC1D15 (TBC1 domain family member 15 [Source:HGNC Symbol;Acc:HGNC:25694]) HSP 1 Score: 357.451 bits (916), Expect = 1.161e-113 Identity = 193/506 (38.14%), Postives = 306/506 (60.47%), Query Frame = 1
Query: 217 LEDLKSFKRSKMTVGNFNSYMIFFMKDGTSHPMMVFRDGGTKNLMDKLENYLSITKSNKERSLFLTELRREDAVFQSFESL-----------GMFSNTKEIQASKYSQPVSNTKEKIWSGLANIGAITNQFIRSI-PNDQYSHIRDLLR-EDAFGIPIEGHRLNTREDQESGFEIISKPVRIELPHPSPIQRRPPLTESEWKKHLSPDGTVTCVEQLMEKIFKGGIEMSLRSTVWKYLLNFYKWDYSLEKNHEMSRRKNDIYHKLKFQWRSIFMEQEDRFTPFRERKSIIEKDMLRTDRALEFYSDEQG-NLQLIYNILMSYSMYNFDLGYVQGMNDILAPILFLINDEVDAFWCFTNLMDTLEPNFTQEQLGIKKQFRQLYTLVQIFDPEFAEYLDANGCKEMLFCFRWLLVKFKRELSYENTMLLWEVLWTNYRCINFHLIFALSVLLHEKNHIMENKYGFNEILKHVNDLKLNDDLENHLCRAESLYLQ------LDQIWCQI 1674
L DLKS K++K +G SY++F +KD P + F G +K L++ LE Y+ + +S +++ L + + ++ QSFE+L G+ K + A + + + K+ + + +TN S+ +D +H R D I G ++N +E E GFE+I+ RI+L +QRR P++ EW K++ +G + V+ + + IF+GG+ +LR WK+LL ++ WD + E+ ++ ++K D Y ++K QW+SI EQE R + R+ +S+IEKD+ RTDR +FY + L L+++ILM+Y MY+FDLGYVQGM+D+L+P+L+++ +EVDAFWCF + MD + NF ++ G+K Q QL TL+++ D F YL++ + FCFRWLL++FKRE S+ + + LWEV+WT C NFHL+ ++L EK IME YGFNEILKH+N+L + D+E+ LC+AE++ LQ L Q C+I
Sbjct: 132 LTDLKSIKQNKEGMGW--SYLVFCLKDDVVLPALHFHQGDSKLLIESLEKYVVLCESPQDKRTLLVNCQNK-SLSQSFENLLDEPAYGLIQAGLLDRRKLLWAIHHWKKIK--KDPYTATMIGFSKVTNYIFDSLRGSDPSTHQRPPSEMADFLSDAIPGLKINQQE--EPGFEVIT---RIDLGERPVVQRREPVSLEEWTKNIDSEGRILNVDNMKQMIFRGGLSHALRKQAWKFLLGYFPWDSTKEERTQLQKQKTDEYFRMKLQWKSISQEQEKRNSRLRDYRSLIEKDVNRTDRTNKFYEGQDNPGLILLHDILMTYCMYDFDLGYVQGMSDLLSPLLYVMENEVDAFWCFASYMDQMHQNFEEQMQGMKTQLIQLSTLLRLLDSGFCSYLESQDSGYLYFCFRWLLIRFKREFSFLDILRLWEVMWTELPCTNFHLLLCCAILESEKQQIMEKHYGFNEILKHINELSMKIDVEDILCKAEAISLQMVKCKELPQAVCEI 627
BLAST of TBC1 domain family member 17 vs. Ensembl Human
Match: TBC1D15 (TBC1 domain family member 15 [Source:HGNC Symbol;Acc:HGNC:25694]) HSP 1 Score: 357.066 bits (915), Expect = 1.287e-113 Identity = 191/495 (38.59%), Postives = 300/495 (60.61%), Query Frame = 1
Query: 217 LEDLKSFKRSKMTVGNFNSYMIFFMKDGTSHPMMVFRDGGTKNLMDKLENYLSITKSNKERSLFLTELRREDAVFQSFESLGMFSNTKEIQASKYSQPVSNTKEKIWSGLANIGAITNQFIRSI-PNDQYSHIRDLLR-EDAFGIPIEGHRLNTREDQESGFEIISKPVRIELPHPSPIQRRPPLTESEWKKHLSPDGTVTCVEQLMEKIFKGGIEMSLRSTVWKYLLNFYKWDYSLEKNHEMSRRKNDIYHKLKFQWRSIFMEQEDRFTPFRERKSIIEKDMLRTDRALEFYSDEQG-NLQLIYNILMSYSMYNFDLGYVQGMNDILAPILFLINDEVDAFWCFTNLMDTLEPNFTQEQLGIKKQFRQLYTLVQIFDPEFAEYLDANGCKEMLFCFRWLLVKFKRELSYENTMLLWEVLWTNYRCINFHLIFALSVLLHEKNHIMENKYGFNEILKHVNDLKLNDDLENHLCRAESLYLQ------LDQIWCQI 1674
L DLKS K++K +G SY++F +KD P + F G +K L++ LE Y+ + +S +++ L + + ++ QSFE+L + Y K+ + + +TN S+ +D +H R D I G ++N +E E GFE+I+ RI+L +QRR P++ EW K++ +G + V+ + + IF+GG+ +LR WK+LL ++ WD + E+ ++ ++K D Y ++K QW+SI EQE R + R+ +S+IEKD+ RTDR +FY + L L+++ILM+Y MY+FDLGYVQGM+D+L+P+L+++ +EVDAFWCF + MD + NF ++ G+K Q QL TL+++ D F YL++ + FCFRWLL++FKRE S+ + + LWEV+WT C NFHL+ ++L EK IME YGFNEILKH+N+L + D+E+ LC+AE++ LQ L Q C+I
Sbjct: 140 LTDLKSIKQNKEGMGW--SYLVFCLKDDVVLPALHFHQGDSKLLIESLEKYVVLCESPQDKRTLLVNCQNK-SLSQSFENL--------LDEPAYGLIQKIKKDPYTATMIGFSKVTNYIFDSLRGSDPSTHQRPPSEMADFLSDAIPGLKINQQE--EPGFEVIT---RIDLGERPVVQRREPVSLEEWTKNIDSEGRILNVDNMKQMIFRGGLSHALRKQAWKFLLGYFPWDSTKEERTQLQKQKTDEYFRMKLQWKSISQEQEKRNSRLRDYRSLIEKDVNRTDRTNKFYEGQDNPGLILLHDILMTYCMYDFDLGYVQGMSDLLSPLLYVMENEVDAFWCFASYMDQMHQNFEEQMQGMKTQLIQLSTLLRLLDSGFCSYLESQDSGYLYFCFRWLLIRFKREFSFLDILRLWEVMWTELPCTNFHLLLCCAILESEKQQIMEKHYGFNEILKHINELSMKIDVEDILCKAEAISLQMVKCKELPQAVCEI 618
BLAST of TBC1 domain family member 17 vs. Ensembl Human
Match: TBC1D17 (TBC1 domain family member 17 [Source:HGNC Symbol;Acc:HGNC:25699]) HSP 1 Score: 311.997 bits (798), Expect = 3.854e-97 Identity = 181/485 (37.32%), Postives = 280/485 (57.73%), Query Frame = 1
Query: 208 SIDLEDLKSFKRSKMTVGNFNSYMIFFMKDGTSHPMMVFRDGGTKNLMDKLENYLSITKSNKERSLFLTELRREDAVFQSFESLGMFSNTKEIQASKYSQ-PVSNTKEKIWSGLANIGAITNQFIRSIPNDQYSHIRDLLREDAFGIPIEGHRLNTREDQESGFEIISKPVRIEL-PHPSPIQRRPPLTESEWKKHLSPDGTVTCVEQLMEKIFKGGIEMSLRSTVWKYLLNFYKWDYSLEKNHEMSRRKNDIYHKLKFQWRSIFMEQEDRFTPFRERKSIIEKDMLRTDRALEFY-SDEQGNLQLIYNILMSYSMYNFDLGYVQGMNDILAPILFLINDEVDAFWCFTNLMDTLEPNFTQEQLGIKKQFRQLYTLVQIFDPEFAEYLDANGCKEMLFCFRWLLVKFKRELSYENTMLLWEVLWTNYRCINFHLIFALSVLLHEKNHIMENKYGFNEILKHVNDLKLNDDLENHLCRAESLYLQL 1653
S+ L +LKS +RSK G +Y++ + G S P + F GGT+ L+ L YL + S ++ L+L A+ SF L +F S++ Q P S T ++ +TN F ++ DL ++ E GFE+IS +EL P P+ ++R PP+TE EW +H+ P+G + V +L +IF GG+ SLR WK+LL + W+ + E++ R+K D Y ++K QW+S+ EQE R + +S+IE+D+ RTDR +FY E L L+ +IL++Y MY+FDLGYVQGM+D+L+PIL++I +EVDAFWCF M+ ++ NF + Q +K+Q +L L+++ DP ++LD+ + FCFRWLL+ FKRE + + + LWEVLWT N HL+ A ++L E++ +M + +G NEILKH+N+L + +E+ L RAE+L+ QL
Sbjct: 87 SVSLGELKSIRRSK--PGLSWAYLVLVTQAGGSLPALHFHRGGTRALLRVLSRYLLLASSPQDSRLYLVFPHDSSALSNSFHHLQLFDQDSSNVVSRFLQDPYSTT-------FSSFSRVTNFFRGALQPQPEGAASDLPP-------------PPDDEPEPGFEVISC---VELGPRPT-VERGPPVTEEEWARHVGPEGRLQQVPELKNRIFSGGLSPSLRREAWKFLLGYLSWEGTAEEHKAHIRKKTDEYFRMKLQWKSVSPEQERRNSLLHGYRSLIERDVSRTDRTNKFYEGPENPGLGLLNDILLTYCMYHFDLGYVQGMSDLLSPILYVIQNEVDAFWCFCGFMELVQGNFEESQETMKRQLGRLLLLLRVLDPLLCDFLDSQDSGSLCFCFRWLLIWFKREFPFPDVLRLWEVLWTGLPGPNLHLLVACAILDMERDTLMLSGFGSNEILKHINELTMKLSVEDVLTRAEALHRQL 545
BLAST of TBC1 domain family member 17 vs. Ensembl Human
Match: TBC1D17 (TBC1 domain family member 17 [Source:HGNC Symbol;Acc:HGNC:25699]) HSP 1 Score: 312.768 bits (800), Expect = 4.447e-97 Identity = 181/485 (37.32%), Postives = 280/485 (57.73%), Query Frame = 1
Query: 208 SIDLEDLKSFKRSKMTVGNFNSYMIFFMKDGTSHPMMVFRDGGTKNLMDKLENYLSITKSNKERSLFLTELRREDAVFQSFESLGMFSNTKEIQASKYSQ-PVSNTKEKIWSGLANIGAITNQFIRSIPNDQYSHIRDLLREDAFGIPIEGHRLNTREDQESGFEIISKPVRIEL-PHPSPIQRRPPLTESEWKKHLSPDGTVTCVEQLMEKIFKGGIEMSLRSTVWKYLLNFYKWDYSLEKNHEMSRRKNDIYHKLKFQWRSIFMEQEDRFTPFRERKSIIEKDMLRTDRALEFY-SDEQGNLQLIYNILMSYSMYNFDLGYVQGMNDILAPILFLINDEVDAFWCFTNLMDTLEPNFTQEQLGIKKQFRQLYTLVQIFDPEFAEYLDANGCKEMLFCFRWLLVKFKRELSYENTMLLWEVLWTNYRCINFHLIFALSVLLHEKNHIMENKYGFNEILKHVNDLKLNDDLENHLCRAESLYLQL 1653
S+ L +LKS +RSK G +Y++ + G S P + F GGT+ L+ L YL + S ++ L+L A+ SF L +F S++ Q P S T ++ +TN F ++ DL ++ E GFE+IS +EL P P+ ++R PP+TE EW +H+ P+G + V +L +IF GG+ SLR WK+LL + W+ + E++ R+K D Y ++K QW+S+ EQE R + +S+IE+D+ RTDR +FY E L L+ +IL++Y MY+FDLGYVQGM+D+L+PIL++I +EVDAFWCF M+ ++ NF + Q +K+Q +L L+++ DP ++LD+ + FCFRWLL+ FKRE + + + LWEVLWT N HL+ A ++L E++ +M + +G NEILKH+N+L + +E+ L RAE+L+ QL
Sbjct: 120 SVSLGELKSIRRSK--PGLSWAYLVLVTQAGGSLPALHFHRGGTRALLRVLSRYLLLASSPQDSRLYLVFPHDSSALSNSFHHLQLFDQDSSNVVSRFLQDPYSTT-------FSSFSRVTNFFRGALQPQPEGAASDLPP-------------PPDDEPEPGFEVISC---VELGPRPT-VERGPPVTEEEWARHVGPEGRLQQVPELKNRIFSGGLSPSLRREAWKFLLGYLSWEGTAEEHKAHIRKKTDEYFRMKLQWKSVSPEQERRNSLLHGYRSLIERDVSRTDRTNKFYEGPENPGLGLLNDILLTYCMYHFDLGYVQGMSDLLSPILYVIQNEVDAFWCFCGFMELVQGNFEESQETMKRQLGRLLLLLRVLDPLLCDFLDSQDSGSLCFCFRWLLIWFKREFPFPDVLRLWEVLWTGLPGPNLHLLVACAILDMERDTLMLSGFGSNEILKHINELTMKLSVEDVLTRAEALHRQL 578
BLAST of TBC1 domain family member 17 vs. Ensembl Celegans
Match: tbc-14 (TBC (Tre-2/Bub2/Cdc16) domain family [Source:UniProtKB/TrEMBL;Acc:A0A168H1X0]) HSP 1 Score: 303.908 bits (777), Expect = 3.105e-94 Identity = 192/569 (33.74%), Postives = 309/569 (54.31%), Query Frame = 1
Query: 61 SKEYDKELDGTLSLIEHNFRRPNGKIANERFITWKPNIKGE-------------LVKTVRP-----------ISIDLEDLKSFK--RSKMTVGNFNSYMIFFMKDGTSHPMMVFRDGGTKNLMDKLENYLSITKSNKERSLFLTELRREDAVFQSFESLGMFSNTKEIQASKYSQPVSNTKEKIWSGLANIGA-ITNQFIRSIPND-----QYSHIRDLLREDAFGIPIEGHRLNTREDQESGFEIISKPVRIELPHPSPIQRRPPLTESEWKKHLSPDGTVTCVE--QLMEKIFKGGIEMSLRSTVWKYLLNFYKWDYSLEKNHEMSRRKNDI---YHKLKFQWRSIFMEQEDRFTPFRERKSIIEKDMLRTDRALEFY-SDEQGNLQLIYNILMSYSMYNFDLGYVQGMNDILAPILFLINDEVDAFWCFTNLMDTLEPNFTQEQLGIKKQFRQLYTLVQIFDPEFAEYLDANGCKEMLFCFRWLLVKFKRELSYENTMLLWEVLWTNYRCINFHLIFALSVLLHEKNHIMENKYGFNEILKHVNDLKLNDDLENHLCRAESLYLQL 1653
SKEY + GTLS++E ++ FI WKP+ E +V P S+D+ DL SF+ K G F S + +DG+S + F++ T +D+L+ Y+++ +S+++ L + ++ +A+ +S + M +I S++ Q N +G + I + + +Q I S+ ND Q IR L+RE + + ++ D FE++++ +ELP I R P+++ W +G+ ++ L +F+GG+ LR WK LL + +W E + + R+ ++ Y +K QW S+ +QE RFT F +RKS++EKD+ RTDR + F+ D+ NL ++N+LM+Y MYNFDLGYVQGM+D +P+LF++ DEVD FWCF LM+ + NF +Q IK Q QL LV I +P+ A YL++ +M FCFRW+LV FKRE S+ +T LWEVLW+ C F L+ +++L + N I++N++G EILKH+NDL ++ ++ L AE+++ QL
Sbjct: 52 SKEY---IPGTLSIVEK---------SSGVFIEWKPSEDAETSWVMTSDDGNTEMVHARSPEEKQKCGARVAFSMDVNDLSSFRNDEPKRGSGGFPSIRLI-CRDGSSQVPLFFKNTTTAEFLDRLQGYITLRRSHRDSHLVIVVDQKSEALAKS---VSMLDENGDI-LSRFMQ---NPYMTAMTGFSKITSFVQDQVIPSVLNDTDAVTQEEKIR-LMRE----LRLAEEQMRVHSDAAGEFEVVTQ---LELPPRPEIYRELPVSKDLWNSFKLSNGSYDPMKLHHLKMNVFRGGLNAELRKEAWKCLLGYRQWH---ESDTDFQTRRAELAKQYENMKKQWMSVTEDQEKRFTKFVKRKSLVEKDVARTDRTVPFFQGDDNVNLVHLHNVLMTYVMYNFDLGYVQGMSDFASPLLFVMKDEVDTFWCFVGLMELTQKNFETDQAFIKLQMNQLRDLVMIINPKLANYLESEKSDDMYFCFRWVLVWFKREFSFLDTCKLWEVLWSGQPCPRFLLLICVAILDSQTNIIIDNQFGLTEILKHINDLSMHLKVDEILTAAEAIFHQL 589
BLAST of TBC1 domain family member 17 vs. Ensembl Celegans
Match: tbc-14 (TBC (Tre-2/Bub2/Cdc16) domain family [Source:UniProtKB/TrEMBL;Acc:A0A168H1X0]) HSP 1 Score: 301.597 bits (771), Expect = 2.180e-93 Identity = 191/571 (33.45%), Postives = 309/571 (54.12%), Query Frame = 1
Query: 61 SKEYDKELDGTLSLIEHNFRRPNGKIANERFITWKPNIKGE-------------LVKTVRP-----------ISIDLEDLKSFK----RSKMTVGNFNSYMIFFMKDGTSHPMMVFRDGGTKNLMDKLENYLSITKSNKERSLFLTELRREDAVFQSFESLGMFSNTKEIQASKYSQPVSNTKEKIWSGLANIGA-ITNQFIRSIPND-----QYSHIRDLLREDAFGIPIEGHRLNTREDQESGFEIISKPVRIELPHPSPIQRRPPLTESEWKKHLSPDGTVTCVE--QLMEKIFKGGIEMSLRSTVWKYLLNFYKWDYSLEKNHEMSRRKNDI---YHKLKFQWRSIFMEQEDRFTPFRERKSIIEKDMLRTDRALEFY-SDEQGNLQLIYNILMSYSMYNFDLGYVQGMNDILAPILFLINDEVDAFWCFTNLMDTLEPNFTQEQLGIKKQFRQLYTLVQIFDPEFAEYLDANGCKEMLFCFRWLLVKFKRELSYENTMLLWEVLWTNYRCINFHLIFALSVLLHEKNHIMENKYGFNEILKHVNDLKLNDDLENHLCRAESLYLQL 1653
SKEY + GTLS++E ++ FI WKP+ E +V P S+D+ DL SF+ + G F S + +DG+S + F++ T +D+L+ Y+++ +S+++ L + ++ +A+ +S + M +I S++ Q N +G + I + + +Q I S+ ND Q IR L+RE + + ++ D FE++++ +ELP I R P+++ W +G+ ++ L +F+GG+ LR WK LL + +W E + + R+ ++ Y +K QW S+ +QE RFT F +RKS++EKD+ RTDR + F+ D+ NL ++N+LM+Y MYNFDLGYVQGM+D +P+LF++ DEVD FWCF LM+ + NF +Q IK Q QL LV I +P+ A YL++ +M FCFRW+LV FKRE S+ +T LWEVLW+ C F L+ +++L + N I++N++G EILKH+NDL ++ ++ L AE+++ QL
Sbjct: 52 SKEY---IPGTLSIVEK---------SSGVFIEWKPSEDAETSWVMTSDDGNTEMVHARSPEEKQKCGARVAFSMDVNDLSSFRNDEPKRDSGSGGFPSIRLI-CRDGSSQVPLFFKNTTTAEFLDRLQGYITLRRSHRDSHLVIVVDQKSEALAKS---VSMLDENGDI-LSRFMQ---NPYMTAMTGFSKITSFVQDQVIPSVLNDTDAVTQEEKIR-LMRE----LRLAEEQMRVHSDAAGEFEVVTQ---LELPPRPEIYRELPVSKDLWNSFKLSNGSYDPMKLHHLKMNVFRGGLNAELRKEAWKCLLGYRQWH---ESDTDFQTRRAELAKQYENMKKQWMSVTEDQEKRFTKFVKRKSLVEKDVARTDRTVPFFQGDDNVNLVHLHNVLMTYVMYNFDLGYVQGMSDFASPLLFVMKDEVDTFWCFVGLMELTQKNFETDQAFIKLQMNQLRDLVMIINPKLANYLESEKSDDMYFCFRWVLVWFKREFSFLDTCKLWEVLWSGQPCPRFLLLICVAILDSQTNIIIDNQFGLTEILKHINDLSMHLKVDEILTAAEAIFHQL 591
BLAST of TBC1 domain family member 17 vs. Ensembl Celegans
Match: tbc-16 (TBC (Tre-2/Bub2/Cdc16) domain family [Source:UniProtKB/TrEMBL;Acc:Q20600]) HSP 1 Score: 134.035 bits (336), Expect = 1.687e-32 Identity = 92/352 (26.14%), Postives = 178/352 (50.57%), Query Frame = 1
Query: 664 LNTREDQE-SGFEIISKPVRIELPHPSPIQRRP------PLTESEWKKHLSPDGTVTCVEQLMEKIFKGGIEMSLRSTVWKYLLNFYKWDYSLEKNHEMSRRKNDIYHKLKFQWRSIFMEQEDRFTPFRERKSIIEKDMLRTDRALEFYS-DEQGNLQLIYNILMSYSMYNFDLGYVQGMNDILAPILFLINDEVDAFWCFTNLMDTLEPNFTQEQLG----IKKQFRQLYTLVQIFDPEFAEYLDAN--GCKEMLFCFRWLLVKFKRELSYENTMLLWEVLWTNYRCINFHLIFALSVLLHEKNHIMENKYGFNEILKHVNDLKLNDDLENHLCRAESL---YLQLDQIWC 1668
+ R QE S I K + I P + +++ P +T + W+ + + G + + + IF +++ +R VW +LL Y W+ S ++ + KND++ + + + + E+ + ++ I KD++RTDR F++ D N +++ NIL++Y++ D+ Y+QGM+D+LAP+L + DEVD+++CF N M + F+ G ++ L ++++F P+F E+L+ +++F RW+L+ FKRE + +WE W +YR FHL ++++ ++ +EIL L + D L +A L + ++++I C
Sbjct: 342 IKARSVQEGSPSAIADKQLIICQPAVTKVEKDPEEGLFEKITLNTWRSYENKSGVIIDSGTVRKHIFFASMDVEMREKVWPFLLRVYPWESSADQRENI---KNDLFLEYQNIRKRRYRVTENAQARWISIENSIVKDVVRTDRKNPFFAGDNNPNSEIMKNILLNYAVMYPDINYIQGMSDLLAPLLSTLKDEVDSYFCFKNFMQ--QTVFSSTPQGNENLMETNLTYLRNMLRMFVPDFYEHLEKQRPDAMQLMFVHRWILLCFKREFPENYALHIWECCWAHYRTNYFHLFVCVAIVSIYGKDVLTQDLPHDEILLFFASLANHMDATLVLQKARGLLFEFTRMEKIPC 688
BLAST of TBC1 domain family member 17 vs. Ensembl Celegans
Match: tbc-8 (TBC (Tre-2/Bub2/Cdc16) domain family [Source:UniProtKB/TrEMBL;Acc:I2HAA0]) HSP 1 Score: 125.946 bits (315), Expect = 6.894e-30 Identity = 93/340 (27.35%), Postives = 157/340 (46.18%), Query Frame = 1
Query: 760 PLTESEWKKHLSPDGTVTCVEQLMEKIFKGGIE----MSLRSTVWKYLLNFYKWDYSLEKNHEM------------------SRRKN---------------------DIYHKLKFQWRSIFMEQEDRFTPFRERKSIIEKDMLRTDRALEFYSDEQGNLQLIYNILMSYSMYNFDLGYVQGMNDILAPILFLINDEVDAFWCFTNLMDTLEPNFTQEQLGIKKQFRQLYTLVQIFDPE-FAEYLDANGCKEMLFCFRWLLVKFKRELSYENTMLLWEVLWTNYR---CINFHLIFALSVLLHEKNHIMENKYGFNEILKHVNDLKLNDDLENHLCRAES 1638
P+ E WK+ + + T ++ +++++ GIE +R W YLL ++W+ S E E RR++ D++ S ++E+ T FR I+KD+ R DR L F+S+ + NL+ + ++ +Y N + GY QGM D+LAP+L DE CF+ LM F Q G+ K L +L+Q+ DP+ +A D + + + F FRW L+ FKRELSYE T +WEV+W R +F + F L+ + + + ++ N + + +++K N++ D L A +
Sbjct: 336 PVDEKFWKQARA-EPTEENEKEFLKRVYWRGIEGINTKEVRRMAWPYLLGLFEWNESPESRLEQFTSQYWQDIEEWRVLEAEVRRRDEEAFRAARARKAASPVREESCDVFEDPNEPTCSQHYDRENLITLFRANLHRIDKDVERCDRNLMFFSN-KDNLESLRRVMYTYVRRNLEEGYTQGMCDLLAPLLVTFEDEALTLECFSLLMLRQRGKFPQRP-GMSKCLLNLRSLIQVVDPQIYALISDIDYAQALSFAFRWFLLDFKRELSYECTYKVWEVIWAAQRLRITDDFAIFFGLATITNYHDVLITNNFDYTDMIKFFNEMAERHDCSRLLSSART 672
BLAST of TBC1 domain family member 17 vs. Ensembl Celegans
Match: tbc-8 (TBC (Tre-2/Bub2/Cdc16) domain family [Source:UniProtKB/TrEMBL;Acc:I2HAA0]) HSP 1 Score: 125.561 bits (314), Expect = 1.120e-29 Identity = 93/340 (27.35%), Postives = 157/340 (46.18%), Query Frame = 1
Query: 760 PLTESEWKKHLSPDGTVTCVEQLMEKIFKGGIE----MSLRSTVWKYLLNFYKWDYSLEKNHEM------------------SRRKN---------------------DIYHKLKFQWRSIFMEQEDRFTPFRERKSIIEKDMLRTDRALEFYSDEQGNLQLIYNILMSYSMYNFDLGYVQGMNDILAPILFLINDEVDAFWCFTNLMDTLEPNFTQEQLGIKKQFRQLYTLVQIFDPE-FAEYLDANGCKEMLFCFRWLLVKFKRELSYENTMLLWEVLWTNYR---CINFHLIFALSVLLHEKNHIMENKYGFNEILKHVNDLKLNDDLENHLCRAES 1638
P+ E WK+ + + T ++ +++++ GIE +R W YLL ++W+ S E E RR++ D++ S ++E+ T FR I+KD+ R DR L F+S+ + NL+ + ++ +Y N + GY QGM D+LAP+L DE CF+ LM F Q G+ K L +L+Q+ DP+ +A D + + + F FRW L+ FKRELSYE T +WEV+W R +F + F L+ + + + ++ N + + +++K N++ D L A +
Sbjct: 564 PVDEKFWKQARA-EPTEENEKEFLKRVYWRGIEGINTKEVRRMAWPYLLGLFEWNESPESRLEQFTSQYWQDIEEWRVLEAEVRRRDEEAFRAARARKAASPVREESCDVFEDPNEPTCSQHYDRENLITLFRANLHRIDKDVERCDRNLMFFSN-KDNLESLRRVMYTYVRRNLEEGYTQGMCDLLAPLLVTFEDEALTLECFSLLMLRQRGKFPQRP-GMSKCLLNLRSLIQVVDPQIYALISDIDYAQALSFAFRWFLLDFKRELSYECTYKVWEVIWAAQRLRITDDFAIFFGLATITNYHDVLITNNFDYTDMIKFFNEMAERHDCSRLLSSART 900
BLAST of TBC1 domain family member 17 vs. Ensembl Fly
Match: Tbc1d15-17 (gene:FBgn0031233 transcript:FBtr0078125) HSP 1 Score: 290.426 bits (742), Expect = 3.825e-88 Identity = 142/310 (45.81%), Postives = 205/310 (66.13%), Query Frame = 1
Query: 727 LPHPSPIQRRPPLTESEWKKHLSPDGTVTCVEQLMEKIFKGGIEMSLRSTVWKYLLNFYKWDYSLEKNHEMSRRKNDIYHKLKFQWRSIFMEQEDRFTPFRERKSIIEKDMLRTDRALEFYSDEQG-NLQLIYNILMSYSMYNFDLGYVQGMNDILAPILFLINDEVDAFWCFTNLMDTLEPNFTQEQLGIKKQFRQLYTLVQIFDPEFAEYLDANGCKEMLFCFRWLLVKFKRELSYENTMLLWEVLWTNYRCINFHLIFALSVLLHEKNHIMENKYGFNEILKHVNDLKLNDDLENHLCRAESLYLQL 1653
LP ++R PLTE++W + +PDG ++ ++ E IF+GG+ SLR VWK+LLN+Y W + + E ++K+ Y+ +K QW ++ QE F +RERK IEKD+ RTDR+L+F++ E NL L+ ILM+Y MYNFDLGYVQGM+D+LAPIL + +EVD FWCF M+ + NF +Q G+K QF Q+ L++ + Y+ ++ M FCFRWLLV +KREL+ E+ + LWE LWT C NFHL+F++++L E I++++Y F EILKHVN+L N D++ L AE +YLQL
Sbjct: 331 LPDRQRVERGHPLTETQWLEFQTPDGRISDSARIKELIFRGGVVQSLRPEVWKFLLNYYLWSDTHVERIERRKQKSIEYYNMKAQWLAMTTTQEANFCGYRERKCQIEKDVKRTDRSLQFFAGEDNPNLTLLQGILMTYVMYNFDLGYVQGMSDLLAPILEIQVNEVDTFWCFVGFMELVFTNFDIDQAGMKTQFAQIRRLIEFANAPLFNYMRSHDSDNMYFCFRWLLVWYKRELNSEDVLKLWECLWTRLPCPNFHLLFSVAILDQETRVIIDSQYEFTEILKHVNELSGNIDVQKTLQVAEGIYLQL 640
BLAST of TBC1 domain family member 17 vs. Ensembl Fly
Match: Tbc1d15-17 (gene:FBgn0031233 transcript:FBtr0332339) HSP 1 Score: 290.426 bits (742), Expect = 3.825e-88 Identity = 142/310 (45.81%), Postives = 205/310 (66.13%), Query Frame = 1
Query: 727 LPHPSPIQRRPPLTESEWKKHLSPDGTVTCVEQLMEKIFKGGIEMSLRSTVWKYLLNFYKWDYSLEKNHEMSRRKNDIYHKLKFQWRSIFMEQEDRFTPFRERKSIIEKDMLRTDRALEFYSDEQG-NLQLIYNILMSYSMYNFDLGYVQGMNDILAPILFLINDEVDAFWCFTNLMDTLEPNFTQEQLGIKKQFRQLYTLVQIFDPEFAEYLDANGCKEMLFCFRWLLVKFKRELSYENTMLLWEVLWTNYRCINFHLIFALSVLLHEKNHIMENKYGFNEILKHVNDLKLNDDLENHLCRAESLYLQL 1653
LP ++R PLTE++W + +PDG ++ ++ E IF+GG+ SLR VWK+LLN+Y W + + E ++K+ Y+ +K QW ++ QE F +RERK IEKD+ RTDR+L+F++ E NL L+ ILM+Y MYNFDLGYVQGM+D+LAPIL + +EVD FWCF M+ + NF +Q G+K QF Q+ L++ + Y+ ++ M FCFRWLLV +KREL+ E+ + LWE LWT C NFHL+F++++L E I++++Y F EILKHVN+L N D++ L AE +YLQL
Sbjct: 331 LPDRQRVERGHPLTETQWLEFQTPDGRISDSARIKELIFRGGVVQSLRPEVWKFLLNYYLWSDTHVERIERRKQKSIEYYNMKAQWLAMTTTQEANFCGYRERKCQIEKDVKRTDRSLQFFAGEDNPNLTLLQGILMTYVMYNFDLGYVQGMSDLLAPILEIQVNEVDTFWCFVGFMELVFTNFDIDQAGMKTQFAQIRRLIEFANAPLFNYMRSHDSDNMYFCFRWLLVWYKRELNSEDVLKLWECLWTRLPCPNFHLLFSVAILDQETRVIIDSQYEFTEILKHVNELSGNIDVQKTLQVAEGIYLQL 640
BLAST of TBC1 domain family member 17 vs. Ensembl Fly
Match: Tbc1d15-17 (gene:FBgn0031233 transcript:FBtr0332338) HSP 1 Score: 290.426 bits (742), Expect = 3.825e-88 Identity = 142/310 (45.81%), Postives = 205/310 (66.13%), Query Frame = 1
Query: 727 LPHPSPIQRRPPLTESEWKKHLSPDGTVTCVEQLMEKIFKGGIEMSLRSTVWKYLLNFYKWDYSLEKNHEMSRRKNDIYHKLKFQWRSIFMEQEDRFTPFRERKSIIEKDMLRTDRALEFYSDEQG-NLQLIYNILMSYSMYNFDLGYVQGMNDILAPILFLINDEVDAFWCFTNLMDTLEPNFTQEQLGIKKQFRQLYTLVQIFDPEFAEYLDANGCKEMLFCFRWLLVKFKRELSYENTMLLWEVLWTNYRCINFHLIFALSVLLHEKNHIMENKYGFNEILKHVNDLKLNDDLENHLCRAESLYLQL 1653
LP ++R PLTE++W + +PDG ++ ++ E IF+GG+ SLR VWK+LLN+Y W + + E ++K+ Y+ +K QW ++ QE F +RERK IEKD+ RTDR+L+F++ E NL L+ ILM+Y MYNFDLGYVQGM+D+LAPIL + +EVD FWCF M+ + NF +Q G+K QF Q+ L++ + Y+ ++ M FCFRWLLV +KREL+ E+ + LWE LWT C NFHL+F++++L E I++++Y F EILKHVN+L N D++ L AE +YLQL
Sbjct: 331 LPDRQRVERGHPLTETQWLEFQTPDGRISDSARIKELIFRGGVVQSLRPEVWKFLLNYYLWSDTHVERIERRKQKSIEYYNMKAQWLAMTTTQEANFCGYRERKCQIEKDVKRTDRSLQFFAGEDNPNLTLLQGILMTYVMYNFDLGYVQGMSDLLAPILEIQVNEVDTFWCFVGFMELVFTNFDIDQAGMKTQFAQIRRLIEFANAPLFNYMRSHDSDNMYFCFRWLLVWYKRELNSEDVLKLWECLWTRLPCPNFHLLFSVAILDQETRVIIDSQYEFTEILKHVNELSGNIDVQKTLQVAEGIYLQL 640
BLAST of TBC1 domain family member 17 vs. Ensembl Fly
Match: CG8155 (gene:FBgn0034009 transcript:FBtr0087391) HSP 1 Score: 183.341 bits (464), Expect = 3.147e-48 Identity = 96/276 (34.78%), Postives = 160/276 (57.97%), Query Frame = 1
Query: 685 ESGFEIISKPVRIELPHPSPIQRRPPLTESEWKKHLSPDGTVTCVEQLMEKIFKGGIEMSLRSTVWKYLLNFYKWDY---SLEKNHEMS--RRKNDIYHKLKFQWRSIFMEQEDRFTPFRERKSIIEKDMLRTDRALEFY--SDEQGNLQLIYNILMSYSMYNFDLGYVQGMNDILAPILFLINDEVDAFWCFTNLMDTLEPNFTQEQLGIKKQFRQLYTLVQIFDPEFAEYLDANGCKEMLFCFRWLLVKFKRELSYENTMLLWEVLWTN--YRC 1485
E F I+ K + H + + RPP+ +SE++ L G + ++L IF GGI+ SLR VWK+LLN Y +L+ + M RRK++ Y +L+ W++ +++ S+++KD+LRTDR FY SD+ N+ ++NIL +Y++ + + Y QGM+DI +P+L +NDE A+ CF +M + NF + + + ++F L + +DPEF EYL + ++LFC+RWLL++ KRE +E+ + + EV W++ YRC
Sbjct: 171 EKTFSIVQKAFNLSEEHMANLPPRPPMCDSEFRLFLDALGQIQRKDELHRVIFLGGIDPSLRRVVWKHLLNVYPGGANGLALDGHQRMEFMRRKSEQYCRLRDTWKAA-VKRGSVAGELAYVTSMVKKDVLRTDRLHPFYAGSDDNQNIAALFNILTTYALNHPSVSYCQGMSDIASPLLVTMNDEAQAYICFCAIMSRMRGNFMLDGIAMTQKFAHLTEALSFYDPEFWEYLKSQQADDLLFCYRWLLLELKREFPFEDALRMLEVQWSSLRYRC 445
BLAST of TBC1 domain family member 17 vs. Ensembl Fly
Match: TBC1D16 (gene:FBgn0032249 transcript:FBtr0080043) HSP 1 Score: 157.918 bits (398), Expect = 2.364e-40 Identity = 94/289 (32.53%), Postives = 155/289 (53.63%), Query Frame = 1
Query: 826 LMEKIFKGGIEMSLRSTVWKYLLNFYKWDYSLEKNHEMSRRKNDIYHKLKFQWRSIFMEQEDRFTPFRERKSIIEKDMLRTDRALEFY-SDEQGNLQLIYNILMSYSMYNFDLGYVQGMNDILAPILFLINDEVDAFWCFTNLMDTLEPNFTQEQLGIKKQFRQLYTLVQIFDPEFAEYLDA-NGCKEMLFCFRWLLVKFKRELSYENTMLLWEVLWTNYRCINFHLIFALSVLLHEKNHIMENKYGFNEILKHVNDLKLNDDLENHLCRAESL---YLQLDQIWCQIS 1677
L + +F GG+E SLR TVW +LL Y + + E + K Y ++ + R M E + ++ + ++EKD++RTDR F+ D+ N +++ NIL+++++YN + Y QGM+D+LAP+L + +E + FWCF LM T + L L++I P F ++L+ N E+LFC RWLL+ FKRE + + +WE W+NY FHL L+++ + ++ +E+L H + L + D + L +A L Y QL +I C +S
Sbjct: 380 LRKCVFFGGLEKSLRKTVWPFLLKCYSFSSTFEDRAVLMDIKRQEYEEITRK-RLYSMSPEQQIHFWKTVQIVVEKDVVRTDRTNPFFCGDDNPNTEVMKNILLNFAVYNTGMSYSQGMSDLLAPVLCEVQNESETFWCFVGLMQRAFFVCTPTDRDVDHNLSYLRELIRIMLPHFYKHLEQHNDSMELLFCHRWLLLCFKREFTEAVVIRMWEACWSNYLTDYFHLFLCLAIIAVYADDVVAQNLRPDEMLLHFSSLAMYMDGQLILRKARGLLHQYRQLPKIPCTLS 667
BLAST of TBC1 domain family member 17 vs. Ensembl Zebrafish
Match: tbc1d17 (TBC1 domain family, member 17 [Source:ZFIN;Acc:ZDB-GENE-050522-79]) HSP 1 Score: 335.109 bits (858), Expect = 7.499e-106 Identity = 187/509 (36.74%), Postives = 299/509 (58.74%), Query Frame = 1
Query: 205 ISIDLEDLKSFKRSKMTVGNFNSYMIFFMKDGTSHPMMVFRDGGTKNLMDKLENYLSITKSNKERSLFLTELRREDAVFQSFESLGMFSNTKEIQASKYSQ-PVSNTKEKIWSGLANIGAITNQFIRSIPNDQYSHIRDLLREDAFGIPIEGHRLNTREDQESGFEIISKPVRIELPHPSPIQRRPPLTESEWKKHLSPDGTVTCVEQLMEKIFKGGIEMSLRSTVWKYLLNFYKWDYSLEKNHEMSRRKNDIYHKLKFQWRSIFMEQEDRFTPFRERKSIIEKDMLRTDRALEFYS-DEQGNLQLIYNILMSYSMYNFDLGYVQGMNDILAPILFLINDEVDAFWCFTNLMDTLEPNFTQEQLGIKKQFRQLYTLVQIFDPEFAEYLDANGCKEMLFCFRWLLVKFKRELSYENTMLLWEVLWTNYRCINFHLIFALSVLLHEKNHIMENKYGFNEILKHVNDLKLNDDLENHLCRAESLYLQLDQIWC-QISEETRDILDFRLSNHS 1722
S+ L +L S +R++ ++G ++++ + G P + F GGT+ L+ ++ Y+ + S + LFL A+ QSF+ L +F +T S++ Q P + T +TN F R + S + + +D D+E GFE+I+ + P P ++R PL W++ L P+G VT +++ E +F+GGI LR VWK+LL FY W+ + ++ ++ K D Y ++K QW+S+ EQE R + FR +S+IE+D+ RTDR F+S +E L L++++LM+Y MYNFDLGYVQGM+D+L+P+LF+ +EV++FWC T MD + NF + Q +K+Q QL L++ DPE +YLD+ + FCFRWLL+ FKRE S+E+ + LWEVLWT C NFHL+ A S+L +K ++ + + FN ILKH+N+L + DL++ LC AE++YLQL C ++S + +++L R+ + S
Sbjct: 112 FSLPLSELYSLRRARFSLGR--NFLVLTTRGGDPLPPLHFHRGGTRELLKAMQRYIRLAPSPMDGRLFLAYPHDSGALSQSFDELHLFDDTSADLVSRFIQDPYATT-------FGGFSKVTN-FFRGALRNPESPLNNRSPQDP--------HFPHSADEEPGFELITCGAELG-PRPE-VKRGKPL--DNWEQFLDPEGRVTDPQKVKELVFRGGIVPYLRKEVWKFLLGFYPWNSTTKEREDILMVKTDEYFRMKVQWKSVSEEQEMRNSLFRGYRSLIERDVNRTDRHNSFFSGNENPGLTLLHDVLMTYCMYNFDLGYVQGMSDLLSPLLFVTQNEVESFWCLTGFMDLVHQNFEESQEAMKQQLLQLSLLLRALDPELCDYLDSQDSGSLCFCFRWLLIWFKREFSFEDILSLWEVLWTRLPCENFHLLMACSILESQKEELIGSNHDFNSILKHINELTMKLDLQSVLCGAEAIYLQLTH--CKELSPKVQEVLGLRIPSGS 596
BLAST of TBC1 domain family member 17 vs. Ensembl Zebrafish
Match: tbc1d15 (TBC1 domain family, member 15 [Source:ZFIN;Acc:ZDB-GENE-041111-251]) HSP 1 Score: 329.331 bits (843), Expect = 2.106e-103 Identity = 183/464 (39.44%), Postives = 279/464 (60.13%), Query Frame = 1
Query: 271 SYMIFFMKDGTSHPMMVFRDGGTKNLMDKLENYLSITKSNKERSLFLTELRREDAVFQSFESLGMFSNTKEIQASKYSQPVSNTKEKIWSGLANIGAITNQFIRSIPNDQYSHIRDLLRE--DAFGIPIEGHRLNTREDQESGFEIISKPVRIELPHPSPIQRRPPLTESEWKKHLSPDGTVTCVEQLMEKIFKGGIEMSLRSTVWKYLLNFYKWDYSLEKNHEMSRRKNDIYHKLKFQWRSIFMEQEDRFTPFRERKSIIEKDMLRTDRALEFYSD-EQGNLQLIYNILMSYSMYNFDLGYVQGMNDILAPILFLINDEVDAFWCFTNLMDTLEPNFTQEQLGIKKQFRQLYTLVQIFDPEFAEYLDANGCKEMLFCFRWLLVKFKRELSYENTMLLWEVLWTNYRCINFHLIFALSVLLHEKNHIMENKYGFNEILKHVNDLKLNDDLENHLCRAESLYLQL 1653
SY+ F +KDGT+ P + F GG+K +D L + I +S + S+ + + A QSFE+L +N +Q K K+ + L +TN + + + E D G I G +N +E E GFE+I+ R++L +QR P+T EW K+ +G +T + L + IFKGG+ ++R WK+LL ++ W + E+ + +RK D Y ++K QW+S+ EQE R + R+ +S+IEKD+ RTDR +FY + L L+++ILM+Y MY+FDLGYVQGM+D+L+PILF++ +EVDAFWCF + MD + NF ++ G+K Q QL TL+++ D F YL+A + FCFRWLL++FKREL +++ + LWEV+WT C NFHL+ ++L EK IM+ KYGFNEILKH+N+L + D+E L ++ES+ +Q+
Sbjct: 143 SYLTFRLKDGTALPAIHFHQGGSKAFLDSLRKSVQINESPDDESVLIVSTYSK-AFSQSFENLLDDTNYGFVQKFK--------KDPYTTTLGGFSKVTNYLFDAFRAPELECQQRPAEEVADVLGELIPGLEINQQE--EPGFEVIT---RLDLGPRPEMQRTGPVTMEEWAKYQDLEGRMTNLPHLKDAIFKGGLCHAVRKEAWKFLLGYFPWSSTHEERKLLQKRKTDEYFRMKLQWKSVSEEQERRNSRLRDYRSLIEKDVNRTDRNNKFYEGLDNPGLILLHDILMTYCMYDFDLGYVQGMSDLLSPILFVMENEVDAFWCFVSFMDEMHENFEEQMQGMKTQLIQLSTLLRLLDLAFWNYLEAQDSGYLYFCFRWLLIRFKRELHFQDVLRLWEVMWTRLPCQNFHLLVCCAILDSEKQKIMDRKYGFNEILKHINELSMKLDIEEILSKSESICMQI 592
BLAST of TBC1 domain family member 17 vs. Ensembl Zebrafish
Match: BX323598.1 (pep chromosome:GRCz11:CHR_ALT_CTG18_2_6:16991192:17001129:-1 gene:ENSDARG00000109706.1 transcript:ENSDART00000191163.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:BX323598.1) HSP 1 Score: 294.278 bits (752), Expect = 5.585e-94 Identity = 148/342 (43.27%), Postives = 228/342 (66.67%), Query Frame = 1
Query: 664 LNTREDQESGFEIISKPVRIELPHPSPIQRRPPLTESEWKKHLSPDGTVTCVEQLMEKIFKGGIEMSLRSTVWKYLLNFYKWDYSLEKNHEMSRRKNDIYHKLKFQWRSIFMEQEDRFTPFRERKSIIEKDMLRTDRALEFYSD-EQGNLQLIYNILMSYSMYNFDLGYVQGMNDILAPILFLINDEVDAFWCFTNLMDTLEPNFTQEQLGIKKQFRQLYTLVQIFDPEFAEYLDANGCKEMLFCFRWLLVKFKRELSYENTMLLWEVLWTNYRCINFHLIFALSVLLHEKNHIMENKYGFNEILKHVNDLKLNDDLENHLCRAESLYLQLDQIWCQISEET 1686
L + +E GFE+I+ R++L +QR P+T EW K+ +G +T + L + IFKGG+ ++R WK+LL ++ W + E+ + +RK D Y ++K QW+S+ EQE R + R+ +S+IEKD+ RTDR +FY + L L+++ILM+Y MY+FDLGYVQGM+D+L+PILF++ +EVDAFWCF + MD + NF ++ G+K Q QL TL+++ D F YL+A + FCFRWLL++FKREL +++ + LWEV+WT C NFHL+ ++L EK IM+ KYGFNEILKH+N+L + D+E L ++ES+ +Q+ C++ +++
Sbjct: 1 LEINQQEEPGFEVIT---RLDLGPRPEMQRTGPVTMEEWAKYQDLEGRMTNLPHLKDAIFKGGLCHAVRKEAWKFLLGYFPWSSTHEERKLLQKRKTDEYFRMKLQWKSVSEEQERRNSRLRDYRSLIEKDVNRTDRNNKFYEGLDNPGLILLHDILMTYCMYDFDLGYVQGMSDLLSPILFVMENEVDAFWCFVSFMDEMHENFEEQMQGMKTQLIQLSTLLRLLDLAFWNYLEAQDSGYLYFCFRWLLIRFKRELHFQDVLRLWEVMWTRLPCQNFHLLVCCAILDSEKQKIMDRKYGFNEILKHINELSMKLDIEEILSKSESICMQIKS--CKVCQKS 337
BLAST of TBC1 domain family member 17 vs. Ensembl Zebrafish
Match: tbc1d17 (TBC1 domain family, member 17 [Source:ZFIN;Acc:ZDB-GENE-050522-79]) HSP 1 Score: 249.21 bits (635), Expect = 7.490e-74 Identity = 157/508 (30.91%), Postives = 257/508 (50.59%), Query Frame = 1
Query: 205 ISIDLEDLKSFKRSKMTVGNFNSYMIFFMKDGTSHPMMVFRDGGTKNLMDKLENYLSITKSNKERSLFLTELRREDAVFQSFESLGMFSNTKEIQASKYSQ-PVSNTKEKIWSGLANIGAITNQFIRSIPNDQYSHIRDLLREDAFGIPIEGHRLNTREDQESGFEIISKPVRIELPHPSPIQRRPPLTESEWKKHLSPDGTVTCVEQLMEKIFKGGIEMSLRSTVWKYLLNFYKWDYSLEKNHEMSRRKNDIYHKLKFQWRSIFMEQEDRFTPFRERKSIIEKDMLRTDRALEFYSDEQGNLQLIYNILMSYSMYNFDLGYVQGMNDILAPILFLINDEVDAFWCFTNLMDTLEPNFTQEQLGIKKQFRQLYTLVQIFDPEFAEYLDANGCKEMLFCFRWLLVKFKRELSYENTMLLWEVLWTNYRCINFHLIFALSVLLHEKNHIMENKYGFNEILKHVNDLKLNDDLENHLCRAESLYLQLDQIWC-QISEETRDILDFRLSNHS 1722
S+ L +L S +R++ ++G ++++ + G P + F GGT+ L+ ++ Y+ + S + LFL A+ QSF+ L +F +T S++ Q P + T +TN F R + S + + +D D+E GFE+I+ + P P ++R PL W++ L P+G VT +++ E +F+GGI LR VWK+LL FY W+ + ++ ++ K D Y ++K QW KS+ E+ Q M+D+L+P+LF+ +EV++FWC T MD + NF + Q +K+Q QL L++ DPE +YLD+ + FCFRWLL+ FKRE S+E+ + LWEVLWT C NFHL+ A S+L +K ++ + + FN ILKH+N+L + DL++ LC AE++YLQL C ++S + +++L R+ + S
Sbjct: 112 FSLPLSELYSLRRARFSLGR--NFLVLTTRGGDPLPPLHFHRGGTRELLKAMQRYIRLAPSPMDGRLFLAYPHDSGALSQSFDELHLFDDTSADLVSRFIQDPYATT-------FGGFSKVTN-FFRGALRNPESPLNNRSPQDP--------HFPHSADEEPGFELITCGAELG-PRPE-VKRGKPL--DNWEQFLDPEGRVTDPQKVKELVFRGGIVPYLRKEVWKFLLGFYPWNSTTKEREDILMVKTDEYFRMKVQW-----------------KSVSEE---------------------------------------QEMSDLLSPLLFVTQNEVESFWCLTGFMDLVHQNFEESQEAMKQQLLQLSLLLRALDPELCDYLDSQDSGSLCFCFRWLLIWFKREFSFEDILSLWEVLWTRLPCENFHLLMACSILESQKEELIGSNHDFNSILKHINELTMKLDLQSVLCGAEAIYLQLTH--CKELSPKVQEVLGLRIPSGS 539
BLAST of TBC1 domain family member 17 vs. Ensembl Zebrafish
Match: tbc1d17 (TBC1 domain family, member 17 [Source:ZFIN;Acc:ZDB-GENE-050522-79]) HSP 1 Score: 246.899 bits (629), Expect = 4.955e-73 Identity = 158/508 (31.10%), Postives = 262/508 (51.57%), Query Frame = 1
Query: 205 ISIDLEDLKSFKRSKMTVGNFNSYMIFFMKDGTSHPMMVFRDGGTKNLMDKLENYLSITKSNKERSLFLTELRREDAVFQSFESLGMFSNTKEIQASKYSQ-PVSNTKEKIWSGLANIGAITNQFIRSIPNDQYSHIRDLLREDAFGIPIEGHRLNTREDQESGFEIISKPVRIELPHPSPIQRRPPLTESEWKKHLSPDGTVTCVEQLMEKIFKGGIEMSLRSTVWKYLLNFYKWDYSLEKNHEMSRRKNDIYHKLKFQWRSIFMEQEDRFTPFRERKSIIEKDMLRTDRALEFYSDEQGNLQLIYNILMSYSMYNFDLGYVQGMNDILAPILFLINDEVDAFWCFTNLMDTLEPNFTQEQLGIKKQFRQLYTLVQIFDPEFAEYLDANGCKEMLFCFRWLLVKFKRELSYENTMLLWEVLWTNYRCINFHLIFALSVLLHEKNHIMENKYGFNEILKHVNDLKLNDDLENHLCRAESLYLQLDQIWC-QISEETRDILDFRLSNHS 1722
S+ L +L S +R++ ++G ++++ + G P + F GGT+ L+ ++ Y+ + S + LFL A+ QSF+ L +F +T S++ Q P + T +TN F R + S + + +D D+E GFE+I+ + P P ++R PL W++ L P+G VT +++ E +F+GGI LR VWK+LL FY W+ + +ER+ I+ M++TD E++ +++ + + YVQGM+D+L+P+LF+ +EV++FWC T MD + NF + Q +K+Q QL L++ DPE +YLD+ + FCFRWLL+ FKRE S+E+ + LWEVLWT C NFHL+ A S+L +K ++ + + FN ILKH+N+L + DL++ LC AE++YLQL C ++S + +++L R+ + S
Sbjct: 112 FSLPLSELYSLRRARFSLGR--NFLVLTTRGGDPLPPLHFHRGGTRELLKAMQRYIRLAPSPMDGRLFLAYPHDSGALSQSFDELHLFDDTSADLVSRFIQDPYATT-------FGGFSKVTN-FFRGALRNPESPLNNRSPQDP--------HFPHSADEEPGFELITCGAELG-PRPE-VKRGKPL--DNWEQFLDPEGRVTDPQKVKELVFRGGIVPYLRKEVWKFLLGFYPWNSTT-----------------------------------KEREDIL---MVKTD---EYF-----RMKVQWK----------SVSYVQGMSDLLSPLLFVTQNEVESFWCLTGFMDLVHQNFEESQEAMKQQLLQLSLLLRALDPELCDYLDSQDSGSLCFCFRWLLIWFKREFSFEDILSLWEVLWTRLPCENFHLLMACSILESQKEELIGSNHDFNSILKHINELTMKLDLQSVLCGAEAIYLQLTH--CKELSPKVQEVLGLRIPSGS 539
BLAST of TBC1 domain family member 17 vs. Ensembl Xenopus
Match: traf7 (TNF receptor associated factor 7 [Source:Xenbase;Acc:XB-GENE-949626]) HSP 1 Score: 363.229 bits (931), Expect = 3.939e-117 Identity = 193/490 (39.39%), Postives = 286/490 (58.37%), Query Frame = 1
Query: 208 SIDLEDLKSFKRSKMTVGNFNSYMIFFMKDGTSHPMMVFRDGGTKNLMDKLENYLSITKSNKERSLFLTELRREDAVFQSFESLGMFSNTKEIQASKY-SQPVSNTKEKIWSGLANIGAITNQFIRSIPNDQYSHIRDLLREDAFGIPIEGHRLNTREDQESGFEIISKPVRIELPHPSPIQRRPPLTESEWKKHLSPDGTVTCVEQLMEKIFKGGIEMSLRSTVWKYLLNFYKWDYSLEKNHEMSRRKNDIYHKLKFQWRSIFMEQEDRFTPFRERKSIIEKDMLRTDRALEFY-SDEQGNLQLIYNILMSYSMYNFDLGYVQGMNDILAPILFLINDEVDAFWCFTNLMDTLEPNFTQEQLGIKKQFRQLYTLVQIFDPEFAEYLDANGCKEMLFCFRWLLVKFKRELSYENTMLLWEVLWTNYRCINFHLIFALSVLLHEKNHIMENKYGFNEILKHVNDLKLNDDLENHLCRAESLYLQLDQIWCQ 1671
+I L DLKS ++SK +G SY+IF KDG SH + F GGTK L+ L Y+ + S K+ LFL A+ SF+ L +F + S++ P + T +TN F ++ +H R + E A G+ + E GFE+I+ ++EL + R+ P++E EW+ + P+G V VE L +IF GG+ R WK+LL +Y W+ ++E+ R K D Y ++K QW+S+ +QE R T R +S+IE+D+ RTDR +FY ++ L L+ ++LM+Y MYNFDLGYVQGM+D+L+P+LF+ +EVDAFWCF MD + NF + Q +KKQ QL L+++ DP ++LD+ + CFRWLL+ FKRE S+++ +LLWEVLWT +NFHL+ +L E+ +M + YGFNEILKH+N+L + +E+ LCRAE+L+ QL CQ
Sbjct: 56 TISLADLKSIRKSKPGLGW--SYLIFITKDGISHQALHFHQGGTKALLKALRKYIILATSPKDSRLFLVYPHDSHALSHSFDELQLFDDGSFYLFSRFFGDPYTAT-------FGGFSKVTNFFRGALRPQDGAHQRPV-SEMAVGL-----------EDEPGFEVIT--CQVELGERPVVHRQEPVSEQEWESYFDPEGHVVEVEALKRRIFSGGLSPGTRKEAWKFLLGYYSWNSTVEERKTTVREKTDEYFRMKLQWKSVTEDQEKRNTLLRGYRSLIERDVSRTDRNNKFYEGNDNPGLGLLNDVLMTYCMYNFDLGYVQGMSDLLSPVLFVTQNEVDAFWCFAGFMDLVHHNFEESQESMKKQLAQLNLLLRVLDPVLCDFLDSKDSGNLSCCFRWLLIWFKREFSFQDILLLWEVLWTGLPSLNFHLLVGCGILDLEREALMNSDYGFNEILKHINELTMKMSVEDILCRAEALHQQLAN--CQ 520
BLAST of TBC1 domain family member 17 vs. Ensembl Xenopus
Match: traf7 (TNF receptor associated factor 7 [Source:Xenbase;Acc:XB-GENE-949626]) HSP 1 Score: 365.155 bits (936), Expect = 5.802e-117 Identity = 192/485 (39.59%), Postives = 285/485 (58.76%), Query Frame = 1
Query: 208 SIDLEDLKSFKRSKMTVGNFNSYMIFFMKDGTSHPMMVFRDGGTKNLMDKLENYLSITKSNKERSLFLTELRREDAVFQSFESLGMFSNTKEIQASKY-SQPVSNTKEKIWSGLANIGAITNQFIRSIPNDQYSHIRDLLREDAFGIPIEGHRLNTREDQESGFEIISKPVRIELPHPSPIQRRPPLTESEWKKHLSPDGTVTCVEQLMEKIFKGGIEMSLRSTVWKYLLNFYKWDYSLEKNHEMSRRKNDIYHKLKFQWRSIFMEQEDRFTPFRERKSIIEKDMLRTDRALEFY-SDEQGNLQLIYNILMSYSMYNFDLGYVQGMNDILAPILFLINDEVDAFWCFTNLMDTLEPNFTQEQLGIKKQFRQLYTLVQIFDPEFAEYLDANGCKEMLFCFRWLLVKFKRELSYENTMLLWEVLWTNYRCINFHLIFALSVLLHEKNHIMENKYGFNEILKHVNDLKLNDDLENHLCRAESLYLQLD 1656
+I L DLKS ++SK +G SY+IF KDG SH + F GGTK L+ L Y+ + S K+ LFL A+ SF+ L +F + S++ P + T +TN F ++ +H R + E A G+ + E GFE+I+ ++EL + R+ P++E EW+ + P+G V VE L +IF GG+ R WK+LL +Y W+ ++E+ R K D Y ++K QW+S+ +QE R T R +S+IE+D+ RTDR +FY ++ L L+ ++LM+Y MYNFDLGYVQGM+D+L+P+LF+ +EVDAFWCF MD + NF + Q +KKQ QL L+++ DP ++LD+ + CFRWLL+ FKRE S+++ +LLWEVLWT +NFHL+ +L E+ +M + YGFNEILKH+N+L + +E+ LCRAE+L+ QLD
Sbjct: 130 TISLADLKSIRKSKPGLGW--SYLIFITKDGISHQALHFHQGGTKALLKALRKYIILATSPKDSRLFLVYPHDSHALSHSFDELQLFDDGSFYLFSRFFGDPYTAT-------FGGFSKVTNFFRGALRPQDGAHQRPV-SEMAVGL-----------EDEPGFEVIT--CQVELGERPVVHRQEPVSEQEWESYFDPEGHVVEVEALKRRIFSGGLSPGTRKEAWKFLLGYYSWNSTVEERKTTVREKTDEYFRMKLQWKSVTEDQEKRNTLLRGYRSLIERDVSRTDRNNKFYEGNDNPGLGLLNDVLMTYCMYNFDLGYVQGMSDLLSPVLFVTQNEVDAFWCFAGFMDLVHHNFEESQESMKKQLAQLNLLLRVLDPVLCDFLDSKDSGNLSCCFRWLLIWFKREFSFQDILLLWEVLWTGLPSLNFHLLVGCGILDLEREALMNSDYGFNEILKHINELTMKMSVEDILCRAEALHQQLD 591
BLAST of TBC1 domain family member 17 vs. Ensembl Xenopus
Match: traf7 (TNF receptor associated factor 7 [Source:Xenbase;Acc:XB-GENE-949626]) HSP 1 Score: 362.844 bits (930), Expect = 8.809e-117 Identity = 193/490 (39.39%), Postives = 286/490 (58.37%), Query Frame = 1
Query: 208 SIDLEDLKSFKRSKMTVGNFNSYMIFFMKDGTSHPMMVFRDGGTKNLMDKLENYLSITKSNKERSLFLTELRREDAVFQSFESLGMFSNTKEIQASKY-SQPVSNTKEKIWSGLANIGAITNQFIRSIPNDQYSHIRDLLREDAFGIPIEGHRLNTREDQESGFEIISKPVRIELPHPSPIQRRPPLTESEWKKHLSPDGTVTCVEQLMEKIFKGGIEMSLRSTVWKYLLNFYKWDYSLEKNHEMSRRKNDIYHKLKFQWRSIFMEQEDRFTPFRERKSIIEKDMLRTDRALEFY-SDEQGNLQLIYNILMSYSMYNFDLGYVQGMNDILAPILFLINDEVDAFWCFTNLMDTLEPNFTQEQLGIKKQFRQLYTLVQIFDPEFAEYLDANGCKEMLFCFRWLLVKFKRELSYENTMLLWEVLWTNYRCINFHLIFALSVLLHEKNHIMENKYGFNEILKHVNDLKLNDDLENHLCRAESLYLQLDQIWCQ 1671
+I L DLKS ++SK +G SY+IF KDG SH + F GGTK L+ L Y+ + S K+ LFL A+ SF+ L +F + S++ P + T +TN F ++ +H R + E A G+ + E GFE+I+ ++EL + R+ P++E EW+ + P+G V VE L +IF GG+ R WK+LL +Y W+ ++E+ R K D Y ++K QW+S+ +QE R T R +S+IE+D+ RTDR +FY ++ L L+ ++LM+Y MYNFDLGYVQGM+D+L+P+LF+ +EVDAFWCF MD + NF + Q +KKQ QL L+++ DP ++LD+ + CFRWLL+ FKRE S+++ +LLWEVLWT +NFHL+ +L E+ +M + YGFNEILKH+N+L + +E+ LCRAE+L+ QL CQ
Sbjct: 74 TISLADLKSIRKSKPGLGW--SYLIFITKDGISHQALHFHQGGTKALLKALRKYIILATSPKDSRLFLVYPHDSHALSHSFDELQLFDDGSFYLFSRFFGDPYTAT-------FGGFSKVTNFFRGALRPQDGAHQRPV-SEMAVGL-----------EDEPGFEVIT--CQVELGERPVVHRQEPVSEQEWESYFDPEGHVVEVEALKRRIFSGGLSPGTRKEAWKFLLGYYSWNSTVEERKTTVREKTDEYFRMKLQWKSVTEDQEKRNTLLRGYRSLIERDVSRTDRNNKFYEGNDNPGLGLLNDVLMTYCMYNFDLGYVQGMSDLLSPVLFVTQNEVDAFWCFAGFMDLVHHNFEESQESMKKQLAQLNLLLRVLDPVLCDFLDSKDSGNLSCCFRWLLIWFKREFSFQDILLLWEVLWTGLPSLNFHLLVGCGILDLEREALMNSDYGFNEILKHINELTMKMSVEDILCRAEALHQQLAN--CQ 538
BLAST of TBC1 domain family member 17 vs. Ensembl Xenopus
Match: traf7 (TNF receptor associated factor 7 [Source:Xenbase;Acc:XB-GENE-949626]) HSP 1 Score: 363.229 bits (931), Expect = 2.153e-116 Identity = 193/490 (39.39%), Postives = 286/490 (58.37%), Query Frame = 1
Query: 208 SIDLEDLKSFKRSKMTVGNFNSYMIFFMKDGTSHPMMVFRDGGTKNLMDKLENYLSITKSNKERSLFLTELRREDAVFQSFESLGMFSNTKEIQASKY-SQPVSNTKEKIWSGLANIGAITNQFIRSIPNDQYSHIRDLLREDAFGIPIEGHRLNTREDQESGFEIISKPVRIELPHPSPIQRRPPLTESEWKKHLSPDGTVTCVEQLMEKIFKGGIEMSLRSTVWKYLLNFYKWDYSLEKNHEMSRRKNDIYHKLKFQWRSIFMEQEDRFTPFRERKSIIEKDMLRTDRALEFY-SDEQGNLQLIYNILMSYSMYNFDLGYVQGMNDILAPILFLINDEVDAFWCFTNLMDTLEPNFTQEQLGIKKQFRQLYTLVQIFDPEFAEYLDANGCKEMLFCFRWLLVKFKRELSYENTMLLWEVLWTNYRCINFHLIFALSVLLHEKNHIMENKYGFNEILKHVNDLKLNDDLENHLCRAESLYLQLDQIWCQ 1671
+I L DLKS ++SK +G SY+IF KDG SH + F GGTK L+ L Y+ + S K+ LFL A+ SF+ L +F + S++ P + T +TN F ++ +H R + E A G+ + E GFE+I+ ++EL + R+ P++E EW+ + P+G V VE L +IF GG+ R WK+LL +Y W+ ++E+ R K D Y ++K QW+S+ +QE R T R +S+IE+D+ RTDR +FY ++ L L+ ++LM+Y MYNFDLGYVQGM+D+L+P+LF+ +EVDAFWCF MD + NF + Q +KKQ QL L+++ DP ++LD+ + CFRWLL+ FKRE S+++ +LLWEVLWT +NFHL+ +L E+ +M + YGFNEILKH+N+L + +E+ LCRAE+L+ QL CQ
Sbjct: 117 TISLADLKSIRKSKPGLGW--SYLIFITKDGISHQALHFHQGGTKALLKALRKYIILATSPKDSRLFLVYPHDSHALSHSFDELQLFDDGSFYLFSRFFGDPYTAT-------FGGFSKVTNFFRGALRPQDGAHQRPV-SEMAVGL-----------EDEPGFEVIT--CQVELGERPVVHRQEPVSEQEWESYFDPEGHVVEVEALKRRIFSGGLSPGTRKEAWKFLLGYYSWNSTVEERKTTVREKTDEYFRMKLQWKSVTEDQEKRNTLLRGYRSLIERDVSRTDRNNKFYEGNDNPGLGLLNDVLMTYCMYNFDLGYVQGMSDLLSPVLFVTQNEVDAFWCFAGFMDLVHHNFEESQESMKKQLAQLNLLLRVLDPVLCDFLDSKDSGNLSCCFRWLLIWFKREFSFQDILLLWEVLWTGLPSLNFHLLVGCGILDLEREALMNSDYGFNEILKHINELTMKMSVEDILCRAEALHQQLAN--CQ 581
BLAST of TBC1 domain family member 17 vs. Ensembl Xenopus
Match: traf7 (TNF receptor associated factor 7 [Source:Xenbase;Acc:XB-GENE-949626]) HSP 1 Score: 359.377 bits (921), Expect = 2.526e-115 Identity = 193/496 (38.91%), Postives = 287/496 (57.86%), Query Frame = 1
Query: 208 SIDLEDLKSFKRSKMTVGNFNSYMIFFMKDGTSHPMMVFRDGGTKNLMDKLENYLSITKSNKERSLFLTELRREDAVFQSFESLGMFSNTK----EIQASKYSQPVSNTK---EKIWSGLANIGAITNQFIRSIPNDQYSHIRDLLREDAFGIPIEGHRLNTREDQESGFEIISKPVRIELPHPSPIQRRPPLTESEWKKHLSPDGTVTCVEQLMEKIFKGGIEMSLRSTVWKYLLNFYKWDYSLEKNHEMSRRKNDIYHKLKFQWRSIFMEQEDRFTPFRERKSIIEKDMLRTDRALEFY-SDEQGNLQLIYNILMSYSMYNFDLGYVQGMNDILAPILFLINDEVDAFWCFTNLMDTLEPNFTQEQLGIKKQFRQLYTLVQIFDPEFAEYLDANGCKEMLFCFRWLLVKFKRELSYENTMLLWEVLWTNYRCINFHLIFALSVLLHEKNHIMENKYGFNEILKHVNDLKLNDDLENHLCRAESLYLQLDQIWCQ 1671
+I L DLKS ++SK +G SY+IF KDG SH + F GGTK L+ L Y+ + S K+ LFL A+ SF+ L +F + + Y + ++K + + +TN F ++ +H R + E A G+ + E GFE+I+ IEL + R+ P++E EW+ + P+G V VE L +IF GG+ R WK+LL +Y W+ ++E+ R K D Y ++K QW+S+ +QE R T R +S+IE+D+ RTDR +FY ++ L L+ ++LM+Y MYNFDLGYVQGM+D+L+P+LF+ +EVDAFWCF MD + NF + Q +KKQ QL L+++ DP ++LD+ + CFRWLL+ FKRE S+++ +LLWEVLWT +NFHL+ +L E+ +M + YGFNEILKH+N+L + +E+ LCRAE+L+ QL CQ
Sbjct: 75 TISLADLKSIRKSKPGLGW--SYLIFITKDGISHQALHFHQGGTKALLKALRKYIILATSPKDSRLFLVYPHDSHALSHSFDELQLFDDGSFYLFSVSRLCYCWALYSSKFFGDPYTATFGGFSKVTNFFRGALRPQDGAHQRPV-SEMAVGL-----------EDEPGFEVIT--CVIELGERPVVHRQEPVSEQEWESYFDPEGHVVEVEALKRRIFSGGLSPGTRKEAWKFLLGYYSWNSTVEERKTTVREKTDEYFRMKLQWKSVTEDQEKRNTLLRGYRSLIERDVSRTDRNNKFYEGNDNPGLGLLNDVLMTYCMYNFDLGYVQGMSDLLSPVLFVTQNEVDAFWCFAGFMDLVHHNFEESQESMKKQLAQLNLLLRVLDPVLCDFLDSKDSGNLSCCFRWLLIWFKREFSFQDILLLWEVLWTGLPSLNFHLLVGCGILDLEREALMNSDYGFNEILKHINELTMKMSVEDILCRAEALHQQLAN--CQ 552
BLAST of TBC1 domain family member 17 vs. Ensembl Mouse
Match: Tbc1d15 (TBC1 domain family, member 15 [Source:MGI Symbol;Acc:MGI:1913937]) HSP 1 Score: 364.385 bits (934), Expect = 1.161e-116 Identity = 191/485 (39.38%), Postives = 295/485 (60.82%), Query Frame = 1
Query: 217 LEDLKSFKRSKMTVGNFNSYMIFFMKDGTSHPMMVFRDGGTKNLMDKLENYLSITKSNKERSLFLTELRREDAVFQSFESLGMFSNTKEIQASKYSQPVSNTKEKIWSGLANIGAITNQFIRSI-PNDQYSHIRDLLR-EDAFGIPIEGHRLNTREDQESGFEIISKPVRIELPHPSPIQRRPPLTESEWKKHLSPDGTVTCVEQLMEKIFKGGIEMSLRSTVWKYLLNFYKWDYSLEKNHEMSRRKNDIYHKLKFQWRSIFMEQEDRFTPFRERKSIIEKDMLRTDRALEFYSDEQG-NLQLIYNILMSYSMYNFDLGYVQGMNDILAPILFLINDEVDAFWCFTNLMDTLEPNFTQEQLGIKKQFRQLYTLVQIFDPEFAEYLDANGCKEMLFCFRWLLVKFKRELSYENTMLLWEVLWTNYRCINFHLIFALSVLLHEKNHIMENKYGFNEILKHVNDLKLNDDLENHLCRAESLYLQLDQI 1662
L DLKS K+SK +G SY++F +KD P + F G +K L++ LE Y+ + +S ++ L + + ++ QSFE+L + Y K+ + + +TN S+ +D +H R D I G ++N +E E GFE+I+ RI+L +QRR P++ EW K L P+G + VE + +KIF+GG+ SLR WK+LL ++ WD + E+ ++ ++K D Y ++K QW+S+ QE R + R+ +S+IEKD+ RTDR +FY + L L+++ILM+Y MY+FDLGYVQGM+D+L+P+L+++ +EVDAFWCF + MD + NF ++ G+K Q QL TL+++ D F YL++ + FCFRWLL++FKRE S+ + + LWEV+WT C NFHL+ ++L EK IM YGFNEILKH+N+L + D+E+ LC+AE++ LQ+ Q
Sbjct: 132 LADLKSVKQSKEGMGW--SYLVFCLKDDVMLPALHFHQGDSKLLIESLEKYVVLCESPQDSRTLLVNCQNK-SLSQSFENL--------LDEPAYGLIQKIKKDPYTATMVGFSKVTNYIFDSLRGSDPSTHQRPPSEMADFLSDAIPGLKINQQE--EPGFEVIT---RIDLGERPVVQRREPVSLEEWNKSLDPEGRLVAVESMKQKIFRGGLSHSLRKQAWKFLLGYFPWDSTKEERTQLQKQKTDEYFRMKLQWKSVSEAQEKRNSRLRDYRSLIEKDVNRTDRTNKFYEGQDNPGLILLHDILMTYCMYDFDLGYVQGMSDLLSPLLYVMENEVDAFWCFASYMDQMHQNFEEQMQGMKTQLIQLSTLLRLLDSGFCSYLESQDSGYLYFCFRWLLIRFKREFSFLDILRLWEVMWTELPCKNFHLLLCCAILESEKQQIMAKHYGFNEILKHINELSMKIDVEDILCKAEAISLQMAQC 600
BLAST of TBC1 domain family member 17 vs. Ensembl Mouse
Match: Tbc1d17 (TBC1 domain family, member 17 [Source:MGI Symbol;Acc:MGI:2449973]) HSP 1 Score: 320.087 bits (819), Expect = 4.969e-100 Identity = 180/484 (37.19%), Postives = 276/484 (57.02%), Query Frame = 1
Query: 208 SIDLEDLKSFKRSKMTVGNFNSYMIFFMKDGTSHPMMVFRDGGTKNLMDKLENYLSITKSNKERSLFLTELRREDAVFQSFESLGMFSNTKEIQASKYSQ-PVSNTKEKIWSGLANIGAITNQFIRSIPNDQYSHIRDLLREDAFGIPIEGHRLNTREDQESGFEIISKPVRIELPHPSPIQRRPPLTESEWKKHLSPDGTVTCVEQLMEKIFKGGIEMSLRSTVWKYLLNFYKWDYSLEKNHEMSRRKNDIYHKLKFQWRSIFMEQEDRFTPFRERKSIIEKDMLRTDRALEFY-SDEQGNLQLIYNILMSYSMYNFDLGYVQGMNDILAPILFLINDEVDAFWCFTNLMDTLEPNFTQEQLGIKKQFRQLYTLVQIFDPEFAEYLDANGCKEMLFCFRWLLVKFKRELSYENTMLLWEVLWTNYRCINFHLIFALSVLLHEKNHIMENKYGFNEILKHVNDLKLNDDLENHLCRAESLYLQL 1653
S+ L +LKS +RSK G +Y++ + G S P + F GGT+ L+ L YL + S ++ L+L + A+ SF L +F S++ Q P S T ++ +TN F R L+ G ++ E GFE+IS +EL ++R PP+TE EW +++ P+G + V +L +IF GG+ LR WK+LL + W+ S E++ R+K D Y ++K QW+S+ EQE R + +S+IE+D+ RTDR +FY E L L+++IL++Y MY+FDLGYVQGM+D+L+PILF++ +EVDAFWCF M+ + NF + Q +K+Q QL L+++ D ++LD+ + FCFRWLL+ FKRE + + + LWEVLWT N HL+ A ++L E++ +M + +G NEILKH+N+L + +E+ L RAE+LY QL
Sbjct: 119 SVSLGELKSIRRSK--PGLSWAYLVLVTQAGGSLPALHFHRGGTRALLRVLSRYLLLASSPQDSRLYLVFPQDPSALSDSFHHLQLFDQDSSNVVSRFLQDPYSTT-------FSSFSRVTNFF------------RGALQPHPEGASSPNLPPLPDDEPEPGFEVISC---VELGQRPTVERAPPVTEEEWNRYVGPEGRLQNVPELKNRIFSGGLSPGLRREAWKFLLGYLSWESSAEEHKAHVRKKTDEYFRMKLQWKSVSAEQERRNSLLHGYRSLIERDVSRTDRTNKFYEGPENPGLSLLHDILLTYCMYHFDLGYVQGMSDLLSPILFVVQNEVDAFWCFCGFMELVHGNFEESQETMKRQLGQLLLLLRVLDQPLCDFLDSQDSGSLCFCFRWLLIWFKREFPFPDVLRLWEVLWTGLPGPNLHLLVACAILDMERDTLMLSGFGSNEILKHINELTMKLSVEDVLTRAEALYRQL 578
BLAST of TBC1 domain family member 17 vs. Ensembl Mouse
Match: Tbc1d17 (TBC1 domain family, member 17 [Source:MGI Symbol;Acc:MGI:2449973]) HSP 1 Score: 263.848 bits (673), Expect = 1.067e-79 Identity = 152/422 (36.02%), Postives = 234/422 (55.45%), Query Frame = 1
Query: 205 ISIDLEDLKSFKRSKMTVGNFNSYMIFFMKDGTSHPMMVFRDGGTKNLMDKLENYLSITKSNKERSLFLTELRREDAVFQSFESLGMFSNTKEIQASKYSQ-PVSNTKEKIWSGLANIGAITNQFIRSIPNDQYSHIRDLLREDAFGIPIEGHRLNTREDQESGFEIISKPVRIELPHPSPIQRRPPLTESEWKKHLSPDGTVTCVEQLMEKIFKGGIEMSLRSTVWKYLLNFYKWDYSLEKNHEMSRRKNDIYHKLKFQWRSIFMEQEDRFTPFRERKSIIEKDMLRTDRALEFY-SDEQGNLQLIYNILMSYSMYNFDLGYVQGMNDILAPILFLINDEVDAFWCFTNLMDTLEPNFTQEQLGIKKQFRQLYTLVQIFDPEFAEYLDANGCKEMLFCFRWLLVKFKRELSYENTMLLWEV 1464
S+ L +LKS +RSK G +Y++ + G S P + F GGT+ L+ L YL + S ++ L+L + A+ SF L +F S++ Q P S T ++ +TN F R L+ G ++ E GFE+IS +EL ++R PP+TE EW +++ P+G + V +L +IF GG+ LR WK+LL + W+ S E++ R+K D Y ++K QW+S+ EQE R + +S+IE+D+ RTDR +FY E L L+++IL++Y MY+FDLGYVQGM+D+L+PILF++ +EVDAFWCF M+ + NF + Q +K+Q QL L+++ D ++LD+ + FCFRWLL+ FKRE + + + LWEV
Sbjct: 118 FSVSLGELKSIRRSK--PGLSWAYLVLVTQAGGSLPALHFHRGGTRALLRVLSRYLLLASSPQDSRLYLVFPQDPSALSDSFHHLQLFDQDSSNVVSRFLQDPYSTT-------FSSFSRVTNFF------------RGALQPHPEGASSPNLPPLPDDEPEPGFEVISC---VELGQRPTVERAPPVTEEEWNRYVGPEGRLQNVPELKNRIFSGGLSPGLRREAWKFLLGYLSWESSAEEHKAHVRKKTDEYFRMKLQWKSVSAEQERRNSLLHGYRSLIERDVSRTDRTNKFYEGPENPGLSLLHDILLTYCMYHFDLGYVQGMSDLLSPILFVVQNEVDAFWCFCGFMELVHGNFEESQETMKRQLGQLLLLLRVLDQPLCDFLDSQDSGSLCFCFRWLLIWFKREFPFPDVLRLWEV 515
BLAST of TBC1 domain family member 17 vs. Ensembl Mouse
Match: Tbc1d25 (TBC1 domain family, member 25 [Source:MGI Symbol;Acc:MGI:2444862]) HSP 1 Score: 169.859 bits (429), Expect = 5.699e-45 Identity = 80/243 (32.92%), Postives = 149/243 (61.32%), Query Frame = 1
Query: 754 RPPLTESEWKKHLSPDGTVTCVEQLMEKIFKGGIEMSLRSTVWKYLLNFYKWDYSLEKNHEMSRRKNDIYHKLKFQWRSIFMEQEDRFTPFRERKSIIEKDMLRTDRALEFYS--DEQGNLQLIYNILMSYSMYNFDLGYVQGMNDILAPILFLINDEVDAFWCFTNLMDTLEPNFTQEQLGIKKQFRQLYTLVQIFDPEFAEYLDANGCKEMLFCFRWLLVKFKRELSYENTMLLWEVLWTN 1476
+PPL+++E+ +L+ +G ++ E+L +I+ GG+E SLR VW+YLLN Y + + + +RK+ Y +LK +W ++ F +S + KD+LRTDRA +Y+ ++ +L+ ++++L +Y++ + + Y QGM+D+ +PIL +++ E AF CF +M L NF + + +F L L++ DP+F +YL G ++ FC+RWLL++ KRE ++++ + + EV W++
Sbjct: 68 KPPLSDAEFHTYLNHEGQLSRPEELRLRIYHGGVEPSLRKVVWRYLLNVYPDGLTGRERMDYMKRKSREYEQLKSEWAQRVNPEDLEFI-----RSTVLKDVLRTDRAHPYYAGPEDGPHLRALHDLLTTYAVTHPQVSYCQGMSDLASPILAVMDHEGHAFVCFCGIMKRLAANFHPDGRAMATKFAHLKLLLRHADPDFYQYLQEAGADDLFFCYRWLLLELKREFAFDDALRMLEVTWSS 305
BLAST of TBC1 domain family member 17 vs. Ensembl Mouse
Match: Tbc1d25 (TBC1 domain family, member 25 [Source:MGI Symbol;Acc:MGI:2444862]) HSP 1 Score: 170.244 bits (430), Expect = 2.709e-44 Identity = 80/243 (32.92%), Postives = 149/243 (61.32%), Query Frame = 1
Query: 754 RPPLTESEWKKHLSPDGTVTCVEQLMEKIFKGGIEMSLRSTVWKYLLNFYKWDYSLEKNHEMSRRKNDIYHKLKFQWRSIFMEQEDRFTPFRERKSIIEKDMLRTDRALEFYS--DEQGNLQLIYNILMSYSMYNFDLGYVQGMNDILAPILFLINDEVDAFWCFTNLMDTLEPNFTQEQLGIKKQFRQLYTLVQIFDPEFAEYLDANGCKEMLFCFRWLLVKFKRELSYENTMLLWEVLWTN 1476
+PPL+++E+ +L+ +G ++ E+L +I+ GG+E SLR VW+YLLN Y + + + +RK+ Y +LK +W ++ F +S + KD+LRTDRA +Y+ ++ +L+ ++++L +Y++ + + Y QGM+D+ +PIL +++ E AF CF +M L NF + + +F L L++ DP+F +YL G ++ FC+RWLL++ KRE ++++ + + EV W++
Sbjct: 231 KPPLSDAEFHTYLNHEGQLSRPEELRLRIYHGGVEPSLRKVVWRYLLNVYPDGLTGRERMDYMKRKSREYEQLKSEWAQRVNPEDLEFI-----RSTVLKDVLRTDRAHPYYAGPEDGPHLRALHDLLTTYAVTHPQVSYCQGMSDLASPILAVMDHEGHAFVCFCGIMKRLAANFHPDGRAMATKFAHLKLLLRHADPDFYQYLQEAGADDLFFCYRWLLLELKREFAFDDALRMLEVTWSS 468
BLAST of TBC1 domain family member 17 vs. UniProt/SwissProt
Match: sp|Q9CXF4|TBC15_MOUSE (TBC1 domain family member 15 OS=Mus musculus OX=10090 GN=Tbc1d15 PE=1 SV=1) HSP 1 Score: 364.385 bits (934), Expect = 8.122e-116 Identity = 191/485 (39.38%), Postives = 295/485 (60.82%), Query Frame = 1
Query: 217 LEDLKSFKRSKMTVGNFNSYMIFFMKDGTSHPMMVFRDGGTKNLMDKLENYLSITKSNKERSLFLTELRREDAVFQSFESLGMFSNTKEIQASKYSQPVSNTKEKIWSGLANIGAITNQFIRSI-PNDQYSHIRDLLR-EDAFGIPIEGHRLNTREDQESGFEIISKPVRIELPHPSPIQRRPPLTESEWKKHLSPDGTVTCVEQLMEKIFKGGIEMSLRSTVWKYLLNFYKWDYSLEKNHEMSRRKNDIYHKLKFQWRSIFMEQEDRFTPFRERKSIIEKDMLRTDRALEFYSDEQG-NLQLIYNILMSYSMYNFDLGYVQGMNDILAPILFLINDEVDAFWCFTNLMDTLEPNFTQEQLGIKKQFRQLYTLVQIFDPEFAEYLDANGCKEMLFCFRWLLVKFKRELSYENTMLLWEVLWTNYRCINFHLIFALSVLLHEKNHIMENKYGFNEILKHVNDLKLNDDLENHLCRAESLYLQLDQI 1662
L DLKS K+SK +G SY++F +KD P + F G +K L++ LE Y+ + +S ++ L + + ++ QSFE+L + Y K+ + + +TN S+ +D +H R D I G ++N +E E GFE+I+ RI+L +QRR P++ EW K L P+G + VE + +KIF+GG+ SLR WK+LL ++ WD + E+ ++ ++K D Y ++K QW+S+ QE R + R+ +S+IEKD+ RTDR +FY + L L+++ILM+Y MY+FDLGYVQGM+D+L+P+L+++ +EVDAFWCF + MD + NF ++ G+K Q QL TL+++ D F YL++ + FCFRWLL++FKRE S+ + + LWEV+WT C NFHL+ ++L EK IM YGFNEILKH+N+L + D+E+ LC+AE++ LQ+ Q
Sbjct: 132 LADLKSVKQSKEGMGW--SYLVFCLKDDVMLPALHFHQGDSKLLIESLEKYVVLCESPQDSRTLLVNCQNK-SLSQSFENL--------LDEPAYGLIQKIKKDPYTATMVGFSKVTNYIFDSLRGSDPSTHQRPPSEMADFLSDAIPGLKINQQE--EPGFEVIT---RIDLGERPVVQRREPVSLEEWNKSLDPEGRLVAVESMKQKIFRGGLSHSLRKQAWKFLLGYFPWDSTKEERTQLQKQKTDEYFRMKLQWKSVSEAQEKRNSRLRDYRSLIEKDVNRTDRTNKFYEGQDNPGLILLHDILMTYCMYDFDLGYVQGMSDLLSPLLYVMENEVDAFWCFASYMDQMHQNFEEQMQGMKTQLIQLSTLLRLLDSGFCSYLESQDSGYLYFCFRWLLIRFKREFSFLDILRLWEVMWTELPCKNFHLLLCCAILESEKQQIMAKHYGFNEILKHINELSMKIDVEDILCKAEAISLQMAQC 600
BLAST of TBC1 domain family member 17 vs. UniProt/SwissProt
Match: sp|Q8TC07|TBC15_HUMAN (TBC1 domain family member 15 OS=Homo sapiens OX=9606 GN=TBC1D15 PE=1 SV=2) HSP 1 Score: 357.451 bits (916), Expect = 5.576e-113 Identity = 193/506 (38.14%), Postives = 306/506 (60.47%), Query Frame = 1
Query: 217 LEDLKSFKRSKMTVGNFNSYMIFFMKDGTSHPMMVFRDGGTKNLMDKLENYLSITKSNKERSLFLTELRREDAVFQSFESL-----------GMFSNTKEIQASKYSQPVSNTKEKIWSGLANIGAITNQFIRSI-PNDQYSHIRDLLR-EDAFGIPIEGHRLNTREDQESGFEIISKPVRIELPHPSPIQRRPPLTESEWKKHLSPDGTVTCVEQLMEKIFKGGIEMSLRSTVWKYLLNFYKWDYSLEKNHEMSRRKNDIYHKLKFQWRSIFMEQEDRFTPFRERKSIIEKDMLRTDRALEFYSDEQG-NLQLIYNILMSYSMYNFDLGYVQGMNDILAPILFLINDEVDAFWCFTNLMDTLEPNFTQEQLGIKKQFRQLYTLVQIFDPEFAEYLDANGCKEMLFCFRWLLVKFKRELSYENTMLLWEVLWTNYRCINFHLIFALSVLLHEKNHIMENKYGFNEILKHVNDLKLNDDLENHLCRAESLYLQ------LDQIWCQI 1674
L DLKS K++K +G SY++F +KD P + F G +K L++ LE Y+ + +S +++ L + + ++ QSFE+L G+ K + A + + + K+ + + +TN S+ +D +H R D I G ++N +E E GFE+I+ RI+L +QRR P++ EW K++ +G + V+ + + IF+GG+ +LR WK+LL ++ WD + E+ ++ ++K D Y ++K QW+SI EQE R + R+ +S+IEKD+ RTDR +FY + L L+++ILM+Y MY+FDLGYVQGM+D+L+P+L+++ +EVDAFWCF + MD + NF ++ G+K Q QL TL+++ D F YL++ + FCFRWLL++FKRE S+ + + LWEV+WT C NFHL+ ++L EK IME YGFNEILKH+N+L + D+E+ LC+AE++ LQ L Q C+I
Sbjct: 132 LTDLKSIKQNKEGMGW--SYLVFCLKDDVVLPALHFHQGDSKLLIESLEKYVVLCESPQDKRTLLVNCQNK-SLSQSFENLLDEPAYGLIQAGLLDRRKLLWAIHHWKKIK--KDPYTATMIGFSKVTNYIFDSLRGSDPSTHQRPPSEMADFLSDAIPGLKINQQE--EPGFEVIT---RIDLGERPVVQRREPVSLEEWTKNIDSEGRILNVDNMKQMIFRGGLSHALRKQAWKFLLGYFPWDSTKEERTQLQKQKTDEYFRMKLQWKSISQEQEKRNSRLRDYRSLIEKDVNRTDRTNKFYEGQDNPGLILLHDILMTYCMYDFDLGYVQGMSDLLSPLLYVMENEVDAFWCFASYMDQMHQNFEEQMQGMKTQLIQLSTLLRLLDSGFCSYLESQDSGYLYFCFRWLLIRFKREFSFLDILRLWEVMWTELPCTNFHLLLCCAILESEKQQIMEKHYGFNEILKHINELSMKIDVEDILCKAEAISLQMVKCKELPQAVCEI 627
BLAST of TBC1 domain family member 17 vs. UniProt/SwissProt
Match: sp|Q8BYH7|TBC17_MOUSE (TBC1 domain family member 17 OS=Mus musculus OX=10090 GN=Tbc1d17 PE=1 SV=2) HSP 1 Score: 320.087 bits (819), Expect = 3.476e-99 Identity = 180/484 (37.19%), Postives = 276/484 (57.02%), Query Frame = 1
Query: 208 SIDLEDLKSFKRSKMTVGNFNSYMIFFMKDGTSHPMMVFRDGGTKNLMDKLENYLSITKSNKERSLFLTELRREDAVFQSFESLGMFSNTKEIQASKYSQ-PVSNTKEKIWSGLANIGAITNQFIRSIPNDQYSHIRDLLREDAFGIPIEGHRLNTREDQESGFEIISKPVRIELPHPSPIQRRPPLTESEWKKHLSPDGTVTCVEQLMEKIFKGGIEMSLRSTVWKYLLNFYKWDYSLEKNHEMSRRKNDIYHKLKFQWRSIFMEQEDRFTPFRERKSIIEKDMLRTDRALEFY-SDEQGNLQLIYNILMSYSMYNFDLGYVQGMNDILAPILFLINDEVDAFWCFTNLMDTLEPNFTQEQLGIKKQFRQLYTLVQIFDPEFAEYLDANGCKEMLFCFRWLLVKFKRELSYENTMLLWEVLWTNYRCINFHLIFALSVLLHEKNHIMENKYGFNEILKHVNDLKLNDDLENHLCRAESLYLQL 1653
S+ L +LKS +RSK G +Y++ + G S P + F GGT+ L+ L YL + S ++ L+L + A+ SF L +F S++ Q P S T ++ +TN F R L+ G ++ E GFE+IS +EL ++R PP+TE EW +++ P+G + V +L +IF GG+ LR WK+LL + W+ S E++ R+K D Y ++K QW+S+ EQE R + +S+IE+D+ RTDR +FY E L L+++IL++Y MY+FDLGYVQGM+D+L+PILF++ +EVDAFWCF M+ + NF + Q +K+Q QL L+++ D ++LD+ + FCFRWLL+ FKRE + + + LWEVLWT N HL+ A ++L E++ +M + +G NEILKH+N+L + +E+ L RAE+LY QL
Sbjct: 119 SVSLGELKSIRRSK--PGLSWAYLVLVTQAGGSLPALHFHRGGTRALLRVLSRYLLLASSPQDSRLYLVFPQDPSALSDSFHHLQLFDQDSSNVVSRFLQDPYSTT-------FSSFSRVTNFF------------RGALQPHPEGASSPNLPPLPDDEPEPGFEVISC---VELGQRPTVERAPPVTEEEWNRYVGPEGRLQNVPELKNRIFSGGLSPGLRREAWKFLLGYLSWESSAEEHKAHVRKKTDEYFRMKLQWKSVSAEQERRNSLLHGYRSLIERDVSRTDRTNKFYEGPENPGLSLLHDILLTYCMYHFDLGYVQGMSDLLSPILFVVQNEVDAFWCFCGFMELVHGNFEESQETMKRQLGQLLLLLRVLDQPLCDFLDSQDSGSLCFCFRWLLIWFKREFPFPDVLRLWEVLWTGLPGPNLHLLVACAILDMERDTLMLSGFGSNEILKHINELTMKLSVEDVLTRAEALYRQL 578
BLAST of TBC1 domain family member 17 vs. UniProt/SwissProt
Match: sp|Q9HA65|TBC17_HUMAN (TBC1 domain family member 17 OS=Homo sapiens OX=9606 GN=TBC1D17 PE=1 SV=2) HSP 1 Score: 312.768 bits (800), Expect = 2.113e-96 Identity = 181/485 (37.32%), Postives = 280/485 (57.73%), Query Frame = 1
Query: 208 SIDLEDLKSFKRSKMTVGNFNSYMIFFMKDGTSHPMMVFRDGGTKNLMDKLENYLSITKSNKERSLFLTELRREDAVFQSFESLGMFSNTKEIQASKYSQ-PVSNTKEKIWSGLANIGAITNQFIRSIPNDQYSHIRDLLREDAFGIPIEGHRLNTREDQESGFEIISKPVRIEL-PHPSPIQRRPPLTESEWKKHLSPDGTVTCVEQLMEKIFKGGIEMSLRSTVWKYLLNFYKWDYSLEKNHEMSRRKNDIYHKLKFQWRSIFMEQEDRFTPFRERKSIIEKDMLRTDRALEFY-SDEQGNLQLIYNILMSYSMYNFDLGYVQGMNDILAPILFLINDEVDAFWCFTNLMDTLEPNFTQEQLGIKKQFRQLYTLVQIFDPEFAEYLDANGCKEMLFCFRWLLVKFKRELSYENTMLLWEVLWTNYRCINFHLIFALSVLLHEKNHIMENKYGFNEILKHVNDLKLNDDLENHLCRAESLYLQL 1653
S+ L +LKS +RSK G +Y++ + G S P + F GGT+ L+ L YL + S ++ L+L A+ SF L +F S++ Q P S T ++ +TN F ++ DL ++ E GFE+IS +EL P P+ ++R PP+TE EW +H+ P+G + V +L +IF GG+ SLR WK+LL + W+ + E++ R+K D Y ++K QW+S+ EQE R + +S+IE+D+ RTDR +FY E L L+ +IL++Y MY+FDLGYVQGM+D+L+PIL++I +EVDAFWCF M+ ++ NF + Q +K+Q +L L+++ DP ++LD+ + FCFRWLL+ FKRE + + + LWEVLWT N HL+ A ++L E++ +M + +G NEILKH+N+L + +E+ L RAE+L+ QL
Sbjct: 120 SVSLGELKSIRRSK--PGLSWAYLVLVTQAGGSLPALHFHRGGTRALLRVLSRYLLLASSPQDSRLYLVFPHDSSALSNSFHHLQLFDQDSSNVVSRFLQDPYSTT-------FSSFSRVTNFFRGALQPQPEGAASDLPP-------------PPDDEPEPGFEVISC---VELGPRPT-VERGPPVTEEEWARHVGPEGRLQQVPELKNRIFSGGLSPSLRREAWKFLLGYLSWEGTAEEHKAHIRKKTDEYFRMKLQWKSVSPEQERRNSLLHGYRSLIERDVSRTDRTNKFYEGPENPGLGLLNDILLTYCMYHFDLGYVQGMSDLLSPILYVIQNEVDAFWCFCGFMELVQGNFEESQETMKRQLGRLLLLLRVLDPLLCDFLDSQDSGSLCFCFRWLLIWFKREFPFPDVLRLWEVLWTGLPGPNLHLLVACAILDMERDTLMLSGFGSNEILKHINELTMKLSVEDVLTRAEALHRQL 578
BLAST of TBC1 domain family member 17 vs. UniProt/SwissProt
Match: sp|Q6BU76|GYP7_DEBHA (GTPase-activating protein GYP7 OS=Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / JCM 1990 / NBRC 0083 / IGC 2968) OX=284592 GN=GYP7 PE=3 SV=2) HSP 1 Score: 199.134 bits (505), Expect = 2.056e-53 Identity = 158/582 (27.15%), Postives = 265/582 (45.53%), Query Frame = 1
Query: 208 SIDLEDLKSFKRSKMTVGNFNSYMIFFMKDGTSHPMMVFRDG---------------------------GTKNLMDKLENYLSITKSNKERSLFLTELRRED----AVFQSFESLGMFSNTKEIQASKYSQPVSNTKEKIWSGLANIGAIT-NQFIRSIPNDQYSHIRDLLRE----------DAFGIPIEGHRLNTREDQESGF-------EIISKPVRIEL-----------PHPSPIQRRPPLTESEWKKHLSPDGT-VTCVEQLMEKIFKGGIEMSLRSTVWKYLLNFYKWDYSLEKNHEMSRRKNDIYHKLKFQWRSIFMEQEDRFTPF-RERKSIIEKDMLRTDRALEFY------------------------------SDEQGNLQLIYN--------ILMSYSMYNFDLGYVQGMNDILAPILFLINDEVDAFWCFTNLMDTLEPNFTQEQLGIKKQFRQLYTLVQIFDPEFAEYLDANGCKEMLFCFRWLLVKFKRELSYENTMLLWEVLWTNYRCINFHLIFALSVLLHEKNHIMENKYGFNEILKHVNDLKLNDDLENHLCRAESLYLQL 1653
SI + + S + K +VG + +I +DG P++ F D G + M+ L + + KS+ E S++L D A F+ ++ +N + + ++ +N K K+ +A A T NQ + + + I+ ++ + D+ + + +E+ E EI +K + EL S RR P+++ EW+ G + ++++ ++IF GG+E +R W +LLN Y WD S E+ + Y ++K +W + + + R F +++K IEKD+ RTDR L + D++ ++ I N IL++Y+ +N +LGYVQGM D+L+P+ DE FW F N MD +E NF ++Q G+K Q L LVQ P+ ++L+ ++ F FR LLV FKRE + + + LWE+LWT+Y FHL FAL+VL + I +N F+E+LK++NDL +N +L + L RAE L+L+
Sbjct: 121 SIPISFVYSIQVRKPSVGWWFGSIIINTQDGEKLPIVFFHDDESPSTLKNQKVRNQRFDPFGDNGEMYWGGSDFMNALGKFADVQKSSVEPSVYLINPESNDLRNFAPFKEPKTAKTETNQEPFKLPDVNKFFANAKWKVLETVATFSAKTRNQVLDLVDENAPMPIKQIINKPEVQKIGNEFDSARVYLAKWAAQVKEEAEEAHRKYQLDDEIYNK-INKELGVGSNTEILTDEEVSKTSRRKPISKVEWEGLFDFSGRLIISIDEIKDRIFHGGLEDCIRGEAWLFLLNVYPWDSSAEERKTLRNSFQTAYEEIKLKWVN---DDDKRSVDFWKDQKHRIEKDINRTDRNLSIFQNKKKISISGVGSDRLPTTRESSPETPDEADDDEFDVSNITNPHLFKMREILLTYNEHNVNLGYVQGMTDLLSPLYVTFQDESLTFWAFVNFMDRMERNFLRDQSGMKNQMLTLNELVQFMLPDLFKHLEKCESTDLYFFFRMLLVWFKREFEWSSVLSLWEILWTDYYSGQFHLFFALAVLSDNERIIRQNLSRFDEVLKYMNDLSMNMNLNHLLIRAELLFLRF 698
BLAST of TBC1 domain family member 17 vs. TrEMBL
Match: A0A2C9LS66 (Rab-GAP TBC domain-containing protein OS=Biomphalaria glabrata OX=6526 GN=106052645 PE=4 SV=1) HSP 1 Score: 397.897 bits (1021), Expect = 1.400e-126 Identity = 206/493 (41.78%), Postives = 314/493 (63.69%), Query Frame = 1
Query: 205 ISIDLEDLKSFKRSKMTVGNFNSYMIFFMKDGTSHPMMVFRDGGTKNLMDKLENYLSITKSNKERSLFLTELRREDAVFQSFESLGMFSNTKEIQASKYSQPVSNTKEKIWSGLANIGAITNQFIRS---IPND---QYSHIRDLLREDAFGIPIEGHRLNTREDQESGFEIISKPVRIELPHPSPIQRRPPLTE-SEWKKHLSPDGTVTCVEQLMEKIFKGGIEMSLRSTVWKYLLNFYKWDYSLEKNHEMSRRKNDIYHKLKFQWRSIFMEQEDRFTPFRERKSIIEKDMLRTDRALEFYS-DEQGNLQLIYNILMSYSMYNFDLGYVQGMNDILAPILFLINDEVDAFWCFTNLMDTLEPNFTQEQLGIKKQFRQLYTLVQIFDPEFAEYLDANGCKEMLFCFRWLLVKFKRELSYENTMLLWEVLWTNYRCINFHLIFALSVLLHEKNHIMENKYGFNEILKHVNDLKLNDDLENHLCRAESLYLQLDQ 1659
IS D+ DLKSFKR+ + +Y+IF +KDGT+ P + F +GG+K L+ +LE ++ I +S ++ LF+ + + +SF L +FS++ K+ K+ + + +TN F+R P + S + + L ED G+ I E GFE+++K +LP P P+ +R E ++W DGT++ VE++ E IF+GG++ ++RS VWK+LL FY WD + +K E +RK D Y ++K QW++I EQE RFT +ER+ +I+KD++RTDR +F+S D+ NLQ++Y+ILM+Y MYNFDLGYVQGM+DILAPIL ++ +EVDAFWCF M+ + NF +Q G+K Q Q++ L+Q++DPE YL+++ FCFRW+L+ FKRE + LWEV+WT+ C NFHLI +L++L EK+ +MENK+GF EILKH+ND+ L+ L++ LC+AE ++LQL +
Sbjct: 93 ISFDVLDLKSFKRN--APNHSWAYIIFILKDGTTFPALHFHNGGSKALLKELETFIHIRRSPNDQRLFIVHDHDPEMLSKSFNELSIFSDSSSAYVQKF------MKDPYTATMGGFSKVTN-FLRDNFMAPENLTRPQSEMAEFLHEDIPGMEISNL-------DEPGFEMVTK---TKLP-PRPVVKRSEHLELAKWNSFFDSDGTISQVEEVKEIIFRGGVDPAIRSEVWKFLLGFYDWDSTTKKRQEQRKRKVDDYFRMKLQWKTISSEQERRFTLLKERRGLIDKDVMRTDRTHKFFSGDKNPNLQVLYDILMTYCMYNFDLGYVQGMSDILAPILVVMENEVDAFWCFAGAMERVCHNFEMDQNGMKVQLSQIHKLMQVYDPELCAYLESHDSGNFYFCFRWILIMFKREFHFHEIQRLWEVIWTDLPCQNFHLIISLAILDSEKSTLMENKFGFTEILKHINDISLSIPLDDTLCKAEGIFLQLKE 565
BLAST of TBC1 domain family member 17 vs. TrEMBL
Match: A0A2C9LSD6 (Rab-GAP TBC domain-containing protein OS=Biomphalaria glabrata OX=6526 GN=106052645 PE=4 SV=1) HSP 1 Score: 397.897 bits (1021), Expect = 1.833e-126 Identity = 207/499 (41.48%), Postives = 315/499 (63.13%), Query Frame = 1
Query: 205 ISIDLEDLKSFKRSKMTVGNFNSYMIFFMKDGTSHPMMVFRDGGTKNLMDKLENYLSITKSNKERSLFLTELRREDAVFQSFESLGMFSNTKEIQASKYSQ------PVSNTKEKIWSGLANIGAITNQFIRS---IPND---QYSHIRDLLREDAFGIPIEGHRLNTREDQESGFEIISKPVRIELPHPSPIQRRPPLTE-SEWKKHLSPDGTVTCVEQLMEKIFKGGIEMSLRSTVWKYLLNFYKWDYSLEKNHEMSRRKNDIYHKLKFQWRSIFMEQEDRFTPFRERKSIIEKDMLRTDRALEFYS-DEQGNLQLIYNILMSYSMYNFDLGYVQGMNDILAPILFLINDEVDAFWCFTNLMDTLEPNFTQEQLGIKKQFRQLYTLVQIFDPEFAEYLDANGCKEMLFCFRWLLVKFKRELSYENTMLLWEVLWTNYRCINFHLIFALSVLLHEKNHIMENKYGFNEILKHVNDLKLNDDLENHLCRAESLYLQLDQ 1659
IS D+ DLKSFKR+ + +Y+IF +KDGT+ P + F +GG+K L+ +LE ++ I +S ++ LF+ + + +SF L +FS++ K+ P K+ + + +TN F+R P + S + + L ED G+ I E GFE+++K +LP P P+ +R E ++W DGT++ VE++ E IF+GG++ ++RS VWK+LL FY WD + +K E +RK D Y ++K QW++I EQE RFT +ER+ +I+KD++RTDR +F+S D+ NLQ++Y+ILM+Y MYNFDLGYVQGM+DILAPIL ++ +EVDAFWCF M+ + NF +Q G+K Q Q++ L+Q++DPE YL+++ FCFRW+L+ FKRE + LWEV+WT+ C NFHLI +L++L EK+ +MENK+GF EILKH+ND+ L+ L++ LC+AE ++LQL +
Sbjct: 93 ISFDVLDLKSFKRN--APNHSWAYIIFILKDGTTFPALHFHNGGSKALLKELETFIHIRRSPNDQRLFIVHDHDPEMLSKSFNELSIFSDSSSAYVQKFVSEPHKGFPKKFMKDPYTATMGGFSKVTN-FLRDNFMAPENLTRPQSEMAEFLHEDIPGMEISNL-------DEPGFEMVTK---TKLP-PRPVVKRSEHLELAKWNSFFDSDGTISQVEEVKEIIFRGGVDPAIRSEVWKFLLGFYDWDSTTKKRQEQRKRKVDDYFRMKLQWKTISSEQERRFTLLKERRGLIDKDVMRTDRTHKFFSGDKNPNLQVLYDILMTYCMYNFDLGYVQGMSDILAPILVVMENEVDAFWCFAGAMERVCHNFEMDQNGMKVQLSQIHKLMQVYDPELCAYLESHDSGNFYFCFRWILIMFKREFHFHEIQRLWEVIWTDLPCQNFHLIISLAILDSEKSTLMENKFGFTEILKHINDISLSIPLDDTLCKAEGIFLQLKE 577
BLAST of TBC1 domain family member 17 vs. TrEMBL
Match: A0A1S3JNQ6 (TBC1 domain family member 15 isoform X2 OS=Lingula unguis OX=7574 GN=LOC106174834 PE=4 SV=1) HSP 1 Score: 395.971 bits (1016), Expect = 1.056e-125 Identity = 212/541 (39.19%), Postives = 324/541 (59.89%), Query Frame = 1
Query: 187 VKTVRP---ISIDLEDLKSFKRSKMTVGNFNSYMIFFMKDGTSHPMMVFRDGGTKNLMDKLENYLSITKSNKERSLFLTELRREDAVFQSFESLGMFSNTKEIQASKYSQ-PVSNTKEKIWSGLANIGAITNQFIRSI---PNDQYSHIRDLLREDAFGIPIEGHRLNTREDQESGFEIISKPVRIELPHPSPIQRRPPLTESEWKKHLSPDGTVTCVEQLMEKIFKGGIEMSLRSTVWKYLLNFYKWDYSLEKNHEMSRRKNDIYHKLKFQWRSIFMEQEDRFTPFRERKSIIEKDMLRTDRALEFY-SDEQGNLQLIYNILMSYSMYNFDLGYVQGMNDILAPILFLINDEVDAFWCFTNLMDTLEPNFTQEQLGIKKQFRQLYTLVQIFDPEFAEYLDANGCKEMLFCFRWLLVKFKRELSYENTMLLWEVLWTNYRCINFHLIFALSVLLHEKNHIMENKYGFNEILKHVNDLKLNDDLENHLCRAESLYLQLDQIWCQISEETRDILDF----RLSNHSVSNIVAVQSGKAVADNP 1773
++T RP IS D++DLKSFKRSK ++G SY+IF KDGT+HP + F GG++ +++ +E +LS+ +S LFL A+ +SF+ L +F T + SK+ + P S T +G + + + + + P + D+L E GI I E GF+I+SK EL + R PL+ +W+K++ +G + V++L E IF+GGIE +LR VWK+ L +Y W+ + ++ E+ ++K D Y ++K QW+S+ +Q+ RF+ R+R+S+I+KD+ RTDR ++ D L+L+ +ILM+Y MYNFDLGYVQGM+D+LAPIL ++++EVDAFWCF M+ + NF +Q G+K Q +QL TL+Q+ DP+ YL+++ M FCFRWLL+ FKRE ++ + M LWEVLWT C NFHL+ S+L EK+ + +N +GF EILKH+ND+ +LE L +AE +YLQL ++ ++IL F + S S V+ A P
Sbjct: 89 IQTRRPKQIISFDIKDLKSFKRSKQSLGW--SYIIFIQKDGTTHPALHFHKGGSREMINSMERFLSVQRSPNTPGLFLVHEHDPGALSRSFDELQLFKETSQDLVSKFVKDPYSTT----LTGFSKVTKFLGEVLMTTDTPPVRPSEEVADILHEAIPGITINAQ-------DEPGFDIVSK---CELAERPDVVRSSPLSRLQWEKNMDSEGRIQNVDELQEIIFRGGIEPNLRREVWKFQLQYYDWNSTSKQREEVRKKKVDDYFRMKLQWKSVTEDQKMRFSVLRDRESLIDKDVTRTDRTQTYFMGDPNPKLELLNDILMTYCMYNFDLGYVQGMSDLLAPILVIMDNEVDAFWCFAGFMEIVARNFEMDQKGMKDQLQQLNTLMQLLDPQLYNYLESHESSNMYFCFRWLLILFKREFTFPDIMRLWEVLWTGLPCKNFHLLLCASILDTEKSIMFDNNFGFTEILKHINDISYTIELEPMLTKAEGIYLQLANT-TKLPGPIKEILGFDFDRKGSGDSSKTSTPVEGYSTPASTP 612
BLAST of TBC1 domain family member 17 vs. TrEMBL
Match: A0A1S3JPC1 (TBC1 domain family member 15 isoform X1 OS=Lingula unguis OX=7574 GN=LOC106174834 PE=4 SV=1) HSP 1 Score: 395.971 bits (1016), Expect = 4.114e-125 Identity = 212/541 (39.19%), Postives = 324/541 (59.89%), Query Frame = 1
Query: 187 VKTVRP---ISIDLEDLKSFKRSKMTVGNFNSYMIFFMKDGTSHPMMVFRDGGTKNLMDKLENYLSITKSNKERSLFLTELRREDAVFQSFESLGMFSNTKEIQASKYSQ-PVSNTKEKIWSGLANIGAITNQFIRSI---PNDQYSHIRDLLREDAFGIPIEGHRLNTREDQESGFEIISKPVRIELPHPSPIQRRPPLTESEWKKHLSPDGTVTCVEQLMEKIFKGGIEMSLRSTVWKYLLNFYKWDYSLEKNHEMSRRKNDIYHKLKFQWRSIFMEQEDRFTPFRERKSIIEKDMLRTDRALEFY-SDEQGNLQLIYNILMSYSMYNFDLGYVQGMNDILAPILFLINDEVDAFWCFTNLMDTLEPNFTQEQLGIKKQFRQLYTLVQIFDPEFAEYLDANGCKEMLFCFRWLLVKFKRELSYENTMLLWEVLWTNYRCINFHLIFALSVLLHEKNHIMENKYGFNEILKHVNDLKLNDDLENHLCRAESLYLQLDQIWCQISEETRDILDF----RLSNHSVSNIVAVQSGKAVADNP 1773
++T RP IS D++DLKSFKRSK ++G SY+IF KDGT+HP + F GG++ +++ +E +LS+ +S LFL A+ +SF+ L +F T + SK+ + P S T +G + + + + + P + D+L E GI I E GF+I+SK EL + R PL+ +W+K++ +G + V++L E IF+GGIE +LR VWK+ L +Y W+ + ++ E+ ++K D Y ++K QW+S+ +Q+ RF+ R+R+S+I+KD+ RTDR ++ D L+L+ +ILM+Y MYNFDLGYVQGM+D+LAPIL ++++EVDAFWCF M+ + NF +Q G+K Q +QL TL+Q+ DP+ YL+++ M FCFRWLL+ FKRE ++ + M LWEVLWT C NFHL+ S+L EK+ + +N +GF EILKH+ND+ +LE L +AE +YLQL ++ ++IL F + S S V+ A P
Sbjct: 129 IQTRRPKQIISFDIKDLKSFKRSKQSLGW--SYIIFIQKDGTTHPALHFHKGGSREMINSMERFLSVQRSPNTPGLFLVHEHDPGALSRSFDELQLFKETSQDLVSKFVKDPYSTT----LTGFSKVTKFLGEVLMTTDTPPVRPSEEVADILHEAIPGITINAQ-------DEPGFDIVSK---CELAERPDVVRSSPLSRLQWEKNMDSEGRIQNVDELQEIIFRGGIEPNLRREVWKFQLQYYDWNSTSKQREEVRKKKVDDYFRMKLQWKSVTEDQKMRFSVLRDRESLIDKDVTRTDRTQTYFMGDPNPKLELLNDILMTYCMYNFDLGYVQGMSDLLAPILVIMDNEVDAFWCFAGFMEIVARNFEMDQKGMKDQLQQLNTLMQLLDPQLYNYLESHESSNMYFCFRWLLILFKREFTFPDIMRLWEVLWTGLPCKNFHLLLCASILDTEKSIMFDNNFGFTEILKHINDISYTIELEPMLTKAEGIYLQLANT-TKLPGPIKEILGFDFDRKGSGDSSKTSTPVEGYSTPASTP 652
BLAST of TBC1 domain family member 17 vs. TrEMBL
Match: A0A3S1I1Y8 (Rab-GAP TBC domain-containing protein OS=Elysia chlorotica OX=188477 GN=EGW08_001609 PE=4 SV=1) HSP 1 Score: 394.43 bits (1012), Expect = 1.024e-124 Identity = 215/544 (39.52%), Postives = 329/544 (60.48%), Query Frame = 1
Query: 205 ISIDLEDLKSFKRSKMTVGNFNSYMIFFMKDGTSHPMMVFRDGGTKNLMDKLENYLSITKSNKERSLFLTELRREDAVFQSFESLGMFSNTKE------IQASKYSQPVSNTKEKIWSGLANIGAITNQFIRSI----PNDQY-----SHIRDLLREDAFGIPIEGHRLNTREDQESGFEIISKPVRIELPHPSPIQRRPPLTESEWKKHLSPDGTVTCVEQLMEKIFKGGIEMSLRSTVWKYLLNFYKWDYSLEKNHEMSRRKNDIYHKLKFQWRSIFMEQEDRFTPFRERKSIIEKDMLRTDRALEFYS-DEQGNLQLIYNILMSYSMYNFDLGYVQGMNDILAPILFLINDEVDAFWCFTNLMDTLEPNFTQEQLGIKKQFRQLYTLVQIFDPEFAEYLDANGCKEMLFCFRWLLVKFKRELSYENTMLLWEVLWTNYRCINFHLIFALSVLLHEKNHIMENKYGFNEILKHVNDLKLNDDLENHLCRAESLYLQLDQIWCQISEETRDILDFRLSNH-----SVSNIVAVQSGKAVADNP 1773
IS D+ DLKSFKRS G +Y+IF +KDGT+ P + F +GG+K L+ +LEN++ I +S + LFL + + + QS L +F+++ + SK+ K + L +TN F+R + N+Q+ S + +LL +D G+ I + E GFE+I+K +LP ++R PL+ +W +G ++ VE L + IF+GG++ ++R+ VWK+LL FY WD +K + +RK D Y ++K QW++I EQE RF+ +ER+ +I+KD++RTDR +F++ D+ NLQ++Y+ILM+Y MYNFDLGYVQGM+DIL+PIL ++ +EVDAFWCF M+ + NF +Q G+K Q Q++ L+QI DPE YL+A+ FCFRW+L+ FKRE + LWEV+WT+ C NFHLI +L++L EK+ ++ENK+GF EILKH+ND+ L+ LE L +AE ++LQL + + ++ ++IL H S+ N V + S A P
Sbjct: 90 ISFDILDLKSFKRSAPNHGW--AYIIFILKDGTTFPALHFHNGGSKALLKELENFIYIRRSPNDPRLFLVKDHDPEQLSQSINELSLFTDSSGAYVQNFVNDSKHGLSKKFIKSPYTTTLGGFSKVTN-FLRDVLMTPENNQHLTRPQSEVAELLHDDIPGMEIS-------QLDEPGFEMITK---TKLPARPAVKRGDPLSSPQWNAFFDAEGKISKVEDLKDIIFRGGVDPAIRAEVWKFLLGFYDWDSCSKKRTDQRKRKVDEYFRMKLQWKTISAEQEKRFSLLKERRGLIDKDVMRTDRTHKFFAGDKNPNLQVLYDILMTYCMYNFDLGYVQGMSDILSPILVVMENEVDAFWCFAGAMERVCHNFEMDQNGMKVQLSQIHKLMQIQDPELCAYLEAHDSGNFYFCFRWILIVFKREFHFHEIQRLWEVIWTDRPCSNFHLIISLAILESEKSTLLENKFGFTEILKHINDISLSIPLEETLRKAEGIFLQL-RDYKKLPVSLKEILGLHPPAHLPASQSMENSVFLGSASNSAPPP 619
BLAST of TBC1 domain family member 17 vs. Ensembl Cavefish
Match: tbc1d15 (TBC1 domain family member 15 [Source:NCBI gene;Acc:103046155]) HSP 1 Score: 341.273 bits (874), Expect = 4.773e-108 Identity = 187/464 (40.30%), Postives = 284/464 (61.21%), Query Frame = 1
Query: 271 SYMIFFMKDGTSHPMMVFRDGGTKNLMDKLENYLSITKSNKERSLFLTELRREDAVFQSFESLGMFSNTKEIQASKYSQPVSNTKEKIWSGLANIGAITNQFIRSI-PNDQYSHIRDLLR-EDAFGIPIEGHRLNTREDQESGFEIISKPVRIELPHPSPIQRRPPLTESEWKKHLSPDGTVTCVEQLMEKIFKGGIEMSLRSTVWKYLLNFYKWDYSLEKNHEMSRRKNDIYHKLKFQWRSIFMEQEDRFTPFRERKSIIEKDMLRTDRALEFYSD-EQGNLQLIYNILMSYSMYNFDLGYVQGMNDILAPILFLINDEVDAFWCFTNLMDTLEPNFTQEQLGIKKQFRQLYTLVQIFDPEFAEYLDANGCKEMLFCFRWLLVKFKRELSYENTMLLWEVLWTNYRCINFHLIFALSVLLHEKNHIMENKYGFNEILKHVNDLKLNDDLENHLCRAESLYLQL 1653
SY+IF +KD T+ P + F GG++ +D L + +T+S + ++ L + A QSFE+L +N +Q K P + T L +TN F + P++ R + D G I G +N +E E GFE+I+ R++L +QRR P+ +W KH +G V+ V L IFKGG+ ++R WK+LL++Y WD + E+ + +RK D Y ++K QW+S+ EQE R + R+ KS+IEKD+ RTDR +FY + L L+++ILM+Y MY+FDLGYVQGM+D+L+PIL+++ +EVDAFWCF + MD + NF ++ G+K Q QL TL+++ D F YL+A + FCFRWLL++FKREL +++ + LWEV+WT C NFHL+ ++L EK IM+ YGFNEILKH+N+L + D+E L ++E++Y+Q+
Sbjct: 141 SYLIFCLKDDTTLPAIHFHQGGSQAFLDGLRKSVQLTESPDDENILLVGAYSK-AFSQSFENLLDDTNYGLVQKFK-KDPYTTT-------LGGFSKVTNYFFDAFRPSESECQQRPVEEMADILGELIPGLEINQQE--EPGFEVIT---RVDLGTRPEVQRREPVMMEDWAKHQDSEGRVSNVPHLKHLIFKGGLCHAVRKDAWKFLLDYYPWDSTHEERKNLQKRKTDEYFRMKLQWKSVSEEQEKRNSRLRDYKSLIEKDVNRTDRTNKFYEGLDNPGLILLHDILMTYCMYDFDLGYVQGMSDLLSPILYVMENEVDAFWCFVSFMDQMHENFEEQMQGMKTQLIQLSTLLRLLDLAFWNYLEAQDSGYLYFCFRWLLIRFKRELHFQDVLRLWEVMWTGLPCHNFHLLVCCAILDSEKQKIMDRHYGFNEILKHINELSMKLDIEEILIKSEAIYMQI 590
BLAST of TBC1 domain family member 17 vs. Ensembl Cavefish
Match: tbc1d17 (TBC1 domain family member 17 [Source:NCBI gene;Acc:103046234]) HSP 1 Score: 328.176 bits (840), Expect = 2.602e-103 Identity = 186/509 (36.54%), Postives = 297/509 (58.35%), Query Frame = 1
Query: 208 SIDLEDLKSFKRSKMTVGNFNSYMIFFMKDGTSHPMMVFRDGGTKNLMDKLENYLSITKSNKERSLFLTELRREDAVFQSFESLGMFSNTKEIQASKYSQ-PVSNTKEKIWSGLANIGAITNQFIRSI-PNDQYSHIRDLLREDAFGIPIEGHRLNTREDQESGFEIISKPVRIELPHPSPIQRRPPLTESEWKKHLSPDGTVTCVEQLMEKIFKGGIEMSLRSTVWKYLLNFYKWDYSLEKNHEMSRRKNDIYHKLKFQWRSIFMEQEDRFTPFRERKSIIEKDMLRTDRALEFYS-DEQGNLQLIYNILMSYSMYNFDLGYVQGMNDILAPILFLINDEVDAFWCFTNLMDTLEPNFTQEQLGIKKQFRQLYTLVQIFDPEFAEYLDANGCKEMLFCFRWLLVKFKRELSYENTMLLWEVLWTNYRCINFHLIFALSVLLHEKNHIMENKYGFNEILKHVNDLKLNDDLENHLCRAESLYLQLDQIWC-QISEETRDILDFRLSNHS 1722
S+ L +L S +R++ ++G ++M+ + G P + F GGT+ L ++ Y+ + S + LFL A+ QSF+ L +F + S++ Q P + T +TN F ++ P + H R ++ P D E GFE+I+ + P P + R PL W++ L P+G VT +++ E +F+GGI SLR VWK+LL FY W+ + ++ ++ R K D Y ++K QW+S+ EQE R + R +S+IE+D+ RTDR F+S +E L+L++++LM+Y MYNFDLGYVQGM+D+LAP+LF+ +EV++FWC T MD + NF + Q +K+Q QL L++ DPE +YLD+ + FCFRWLL+ +KRE S+E+ + LWEVLWT C NFHL+ A ++L ++ ++ + + FN ILKH+N+L + DL+ L AE +YLQL Q C ++S + +++L +++ S
Sbjct: 111 SLPLSELYSLRRARFSLGR--NFMVLTSRGGDPLPPLHFHRGGTRELFRAMQRYIRLVPSPVDGRLFLAYPHDSGALSQSFDELQLFDDGSSDLVSRFIQDPYATT-------FGGFSKVTNFFRGALRPPESPLHSRSPPEPNSAHPP----------DDEPGFELITCGAELG-PRPK-VTRGQPL--DNWEQFLDPEGRVTDPQKVKELVFRGGIIPSLRKEVWKFLLGFYPWNSTAKEREDIIRVKTDEYFRMKVQWKSVSEEQEMRNSLLRGYRSLIERDVNRTDRQNSFFSGNENPGLKLLHDVLMTYCMYNFDLGYVQGMSDLLAPLLFVTQNEVESFWCLTGFMDLVHKNFEESQEAMKQQLLQLSLLLKALDPELCDYLDSQDSGSLCFCFRWLLIWYKREFSFEDILNLWEVLWTRLPCENFHLLMACAILESQRGELIGSNHDFNTILKHINELNMKLDLQTVLQGAEGIYLQLAQ--CKELSVKVQEVLGLYVASSS 594
BLAST of TBC1 domain family member 17 vs. Ensembl Cavefish
Match: tbc1d17 (TBC1 domain family member 17 [Source:NCBI gene;Acc:103046234]) HSP 1 Score: 328.176 bits (840), Expect = 2.602e-103 Identity = 186/509 (36.54%), Postives = 297/509 (58.35%), Query Frame = 1
Query: 208 SIDLEDLKSFKRSKMTVGNFNSYMIFFMKDGTSHPMMVFRDGGTKNLMDKLENYLSITKSNKERSLFLTELRREDAVFQSFESLGMFSNTKEIQASKYSQ-PVSNTKEKIWSGLANIGAITNQFIRSI-PNDQYSHIRDLLREDAFGIPIEGHRLNTREDQESGFEIISKPVRIELPHPSPIQRRPPLTESEWKKHLSPDGTVTCVEQLMEKIFKGGIEMSLRSTVWKYLLNFYKWDYSLEKNHEMSRRKNDIYHKLKFQWRSIFMEQEDRFTPFRERKSIIEKDMLRTDRALEFYS-DEQGNLQLIYNILMSYSMYNFDLGYVQGMNDILAPILFLINDEVDAFWCFTNLMDTLEPNFTQEQLGIKKQFRQLYTLVQIFDPEFAEYLDANGCKEMLFCFRWLLVKFKRELSYENTMLLWEVLWTNYRCINFHLIFALSVLLHEKNHIMENKYGFNEILKHVNDLKLNDDLENHLCRAESLYLQLDQIWC-QISEETRDILDFRLSNHS 1722
S+ L +L S +R++ ++G ++M+ + G P + F GGT+ L ++ Y+ + S + LFL A+ QSF+ L +F + S++ Q P + T +TN F ++ P + H R ++ P D E GFE+I+ + P P + R PL W++ L P+G VT +++ E +F+GGI SLR VWK+LL FY W+ + ++ ++ R K D Y ++K QW+S+ EQE R + R +S+IE+D+ RTDR F+S +E L+L++++LM+Y MYNFDLGYVQGM+D+LAP+LF+ +EV++FWC T MD + NF + Q +K+Q QL L++ DPE +YLD+ + FCFRWLL+ +KRE S+E+ + LWEVLWT C NFHL+ A ++L ++ ++ + + FN ILKH+N+L + DL+ L AE +YLQL Q C ++S + +++L +++ S
Sbjct: 111 SLPLSELYSLRRARFSLGR--NFMVLTSRGGDPLPPLHFHRGGTRELFRAMQRYIRLVPSPVDGRLFLAYPHDSGALSQSFDELQLFDDGSSDLVSRFIQDPYATT-------FGGFSKVTNFFRGALRPPESPLHSRSPPEPNSAHPP----------DDEPGFELITCGAELG-PRPK-VTRGQPL--DNWEQFLDPEGRVTDPQKVKELVFRGGIIPSLRKEVWKFLLGFYPWNSTAKEREDIIRVKTDEYFRMKVQWKSVSEEQEMRNSLLRGYRSLIERDVNRTDRQNSFFSGNENPGLKLLHDVLMTYCMYNFDLGYVQGMSDLLAPLLFVTQNEVESFWCLTGFMDLVHKNFEESQEAMKQQLLQLSLLLKALDPELCDYLDSQDSGSLCFCFRWLLIWYKREFSFEDILNLWEVLWTRLPCENFHLLMACAILESQRGELIGSNHDFNTILKHINELNMKLDLQTVLQGAEGIYLQLAQ--CKELSVKVQEVLGLYVASSS 594
BLAST of TBC1 domain family member 17 vs. Ensembl Cavefish
Match: tbc1d17 (TBC1 domain family member 17 [Source:NCBI gene;Acc:103046234]) HSP 1 Score: 291.197 bits (744), Expect = 1.045e-89 Identity = 174/509 (34.18%), Postives = 274/509 (53.83%), Query Frame = 1
Query: 208 SIDLEDLKSFKRSKMTVGNFNSYMIFFMKDGTSHPMMVFRDGGTKNLMDKLENYLSITKSNKERSLFLTELRREDAVFQSFESLGMFSNTKEIQASKYSQ-PVSNTKEKIWSGLANIGAITNQFIRSI-PNDQYSHIRDLLREDAFGIPIEGHRLNTREDQESGFEIISKPVRIELPHPSPIQRRPPLTESEWKKHLSPDGTVTCVEQLMEKIFKGGIEMSLRSTVWKYLLNFYKWDYSLEKNHEMSRRKNDIYHKLKFQWRSIFMEQEDRFTPFRERKSIIEKDMLRTDRALEFYS-DEQGNLQLIYNILMSYSMYNFDLGYVQGMNDILAPILFLINDEVDAFWCFTNLMDTLEPNFTQEQLGIKKQFRQLYTLVQIFDPEFAEYLDANGCKEMLFCFRWLLVKFKRELSYENTMLLWEVLWTNYRCINFHLIFALSVLLHEKNHIMENKYGFNEILKHVNDLKLNDDLENHLCRAESLYLQLDQIWC-QISEETRDILDFRLSNHS 1722
S+ L +L S +R++ ++G ++M+ + G P + F GGT+ L ++ Y+ + S + LFL A+ QSF+ L +F + S++ Q P + T +TN F ++ P + H R ++ P D E GFE+I TC GI SLR VWK+LL FY W+ + ++ ++ R K D Y ++K QW+S+ EQE R + R +S+IE+D+ RTDR F+S +E L+L++++LM+Y MYNFDLGYVQGM+D+LAP+LF+ +EV++FWC T MD + NF + Q +K+Q QL L++ DPE +YLD+ + FCFRWLL+ +KRE S+E+ + LWEVLWT C NFHL+ A ++L ++ ++ + + FN ILKH+N+L + DL+ L AE +YLQL Q C ++S + +++L +++ S
Sbjct: 111 SLPLSELYSLRRARFSLGR--NFMVLTSRGGDPLPPLHFHRGGTRELFRAMQRYIRLVPSPVDGRLFLAYPHDSGALSQSFDELQLFDDGSSDLVSRFIQDPYATT-------FGGFSKVTNFFRGALRPPESPLHSRSPPEPNSAHPP----------DDEPGFELI-----------------------------------TC-----------GIIPSLRKEVWKFLLGFYPWNSTAKEREDIIRVKTDEYFRMKVQWKSVSEEQEMRNSLLRGYRSLIERDVNRTDRQNSFFSGNENPGLKLLHDVLMTYCMYNFDLGYVQGMSDLLAPLLFVTQNEVESFWCLTGFMDLVHKNFEESQEAMKQQLLQLSLLLKALDPELCDYLDSQDSGSLCFCFRWLLIWYKREFSFEDILNLWEVLWTRLPCENFHLLMACAILESQRGELIGSNHDFNTILKHINELNMKLDLQTVLQGAEGIYLQLAQ--CKELSVKVQEVLGLYVASSS 552
BLAST of TBC1 domain family member 17 vs. Ensembl Cavefish
Match: tbc1d16 (TBC1 domain family member 16 [Source:NCBI gene;Acc:103027276]) HSP 1 Score: 170.244 bits (430), Expect = 1.651e-44 Identity = 97/307 (31.60%), Postives = 175/307 (57.00%), Query Frame = 1
Query: 772 SEWKKHLSPDGTVTCVEQLMEKIFKGGIEMSLRSTVWKYLLNFYKWDYSLEKNHEMSRRKNDIYHKLKFQWRSIFMEQEDRFTPFRERKSIIEKDMLRTDRALEFYSDEQG-NLQLIYNILMSYSMYNFDLGYVQGMNDILAPILFLINDEVDAFWCFTNLMDTLEPNFTQEQLGIKKQFRQLYTLVQIFDPEFAEYLDANG--CKEMLFCFRWLLVKFKRELSYENTMLLWEVLWTNYRCINFHLIFALSVLLHEKNHIMENKYGFNEILKHVNDLKLNDDLENHLCRAESLYLQ---LDQIWCQI 1674
S W +HL+ G V +L + IF GGI+ S+R VW +LL++Y +D + E+ +K Y ++ Q R + M E+ +R+ + ++KD++RTDR+ F+ E N++++ IL++Y+++N ++GY QGM+D++AP+L I DE D FWCF LM+ + +++Q L L+++ P F ++L G ++LFC RW+L+ FKRE + +WE W +Y+ FHL +++++ + + E + +++L H ++L ++ + E L +A SL Q L +I C +
Sbjct: 341 SSWLRHLNHSGQVEEEYKLRKAIFFGGIDPSIRGEVWPFLLHYYSYDSTSEEREAWRLQKRSEYQEI--QQRRLSMSPEEHSEFWRKVQFTVDKDVVRTDRSNMFFRGENNPNVEIMRRILLNYAVFNPEMGYCQGMSDLVAPLLTEIQDESDTFWCFVGLMENTIFISSPRDEDMERQLMYLRELLRLMLPRFHQHLMRLGEDGLQLLFCHRWVLLCFKREFPDMEALRMWEACWAHYQTDYFHLFLCVAIIMLYGDDVTEQQLATDQMLLHFSNLSMHMNGELVLRKARSLLYQFRLLPRIPCSL 645
BLAST of TBC1 domain family member 17 vs. Ensembl Sea Lamprey
Match: tbc1d15 (TBC1 domain family, member 15 [Source:ZFIN;Acc:ZDB-GENE-041111-251]) HSP 1 Score: 373.244 bits (957), Expect = 3.564e-121 Identity = 205/509 (40.28%), Postives = 308/509 (60.51%), Query Frame = 1
Query: 208 SIDLEDLKSFKRSKMTVGNFNSYMIFFMKDGTSHPMMVFRDGGTKNLMDKLENYLSITKSNKERSLFLTELRREDAVFQSFESLGMFSNTKEIQASKYSQPVSNTKEKIWSGLANIGAITNQFIR---SIPNDQYSH-----IRDLLREDAFGIPIEGHRLNTREDQESGFEIISKPVRIEL-PHPSPIQRRPPLTESEWKKHLSPDGTVTCVEQLMEKIFKGGIEMSLRSTVWKYLLNFYKWDYSLEKNHEMSRRKNDIYHKLKFQWRSIFMEQEDRFTPFRERKSIIEKDMLRTDRALEFYSDEQG-NLQLIYNILMSYSMYNFDLGYVQGMNDILAPILFLINDEVDAFWCFTNLMDTLEPNFTQEQLGIKKQFRQLYTLVQIFDPEFAEYLDANGCKEMLFCFRWLLVKFKRELSYENTMLLWEVLWTNYRCINFHLIFALSVLLHEKNHIMENKYGFNEILKHVNDLKLNDDLENHLCRAESLYLQLDQIWCQISEETRDILDF 1704
+ L DLKS +++K +G SY+IF ++DGTS P + F GG+K L+ L Y+S+ +S + L L A+ QS + L +F + SK+ K+ + L + +TN F+R + P++ H I DLL E G LN + +E GFE+I+ EL P P+ +QRR P++ EW++++ P+G V V++L I +GG+ SLR VWK++L +Y W + E+ + ++K D Y ++K QW+S+ EQE R + R+ K++IEKD+ RTDR +FY L L+ +ILM+Y MY+FDLGYVQGM+D+L+PIL++ +EVDAFWCF MD + NF + Q G+K Q QL L+ + DP F +YL+ + + FCFRWLL++FKRE S+++ + LWEV+WT C NFHL+ ++L E+ H+M+ K GFNEILKHVN+L + D+E L R +++YLQL Q C+ E R IL+
Sbjct: 113 AFSLSDLKSIRKNKPGLGW--SYLIFIIRDGTSFPALHFHQGGSKALLTALSRYVSLARSPLDSRLTLVHCHDTRALSQSMDELQLFDDGAPHFVSKF------IKDPYTTTLGSFSKVTN-FLRESLAQPHEAPRHRPPNEIADLLNESIPG-------LNINQQEEPGFELITC---TELGPRPN-VQRREPVSTEEWERYMDPEGRVRDVDKLKAAICQGGLAHSLRKEVWKFVLGYYPWTSTTEERKAVVKKKADEYFRMKLQWKSVSEEQEKRNSNLRDYKNLIEKDVNRTDRTNKFYEGSNNPGLTLLNDILMTYCMYDFDLGYVQGMSDLLSPILYVQENEVDAFWCFVGYMDQVHHNFKESQQGMKTQLVQLCQLLHLLDPSFCDYLETHDSGNLYFCFRWLLIRFKREFSFQDILRLWEVMWTGLPCQNFHLLLCCAILDIERQHMMDAKCGFNEILKHVNELSMKLDVEEILKRGQAIYLQLSQ--CK--ELPRSILEI 597
BLAST of TBC1 domain family member 17 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006060.1 (pep scaffold:Pmarinus_7.0:GL483653:11070:13246:1 gene:ENSPMAG00000005481.1 transcript:ENSPMAT00000006060.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 128.642 bits (322), Expect = 1.011e-34 Identity = 71/184 (38.59%), Postives = 108/184 (58.70%), Query Frame = 1
Query: 1045 IEKDMLRTDRALEFYSDEQGNLQLIYNILMSYSMYNFDLGYVQGMNDILAPILFLINDEVDAFWCFTNLMDTLEPNFTQEQLGIKKQFRQLYTLVQIFDPEFAEYLDANG-CKEMLFCFRWLLVKFKRELSYENTMLLWEVLWTNYRCI--NFHLIFALSVLLHEKNHIMENKYGFNEILKHVN 1587
I+KD+ R DR F++ GNL+ + I+ SY + D+GYVQGM D+LAP+L +++DEV A+ CF+ LM + NF Q + F + +L+QI D E E + NG FC+RW L+ FKREL YE+ +WE +W R +F L AL+++ ++ I+EN F +I++ N
Sbjct: 1 IDKDVHRCDRNFWFFT--AGNLERLRRIMCSYVWEHLDVGYVQGMCDLLAPLLVILDDEVLAYSCFSQLMKRMIQNFPQGG-AMDNHFANMRSLIQILDSEIFELMHRNGDYTHFFFCYRWFLLDFKRELVYEDVFAVWEAIWAARRVSSEHFVLFLALALVARYRDIILENNMDFTDIIRFFN 181
BLAST of TBC1 domain family member 17 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000005219.1 (pep scaffold:Pmarinus_7.0:GL483183:6327:16404:1 gene:ENSPMAG00000004730.1 transcript:ENSPMAT00000005219.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 116.701 bits (291), Expect = 1.084e-27 Identity = 57/168 (33.93%), Postives = 100/168 (59.52%), Query Frame = 1
Query: 763 LTESEWKKHLSPDGTVTCVEQLMEKIFKGGIEMSLRSTVWKYLLNFYKWDYSLEKNHEMSRRKNDIYHKLKFQWRSIFMEQEDRFTPFRERKSIIEKDMLRTDRALEFYSDEQG-NLQLIYN---ILMSYSMYNFDLGYVQGMNDILAPILFLINDEVDAFWCFTNLM 1254
L+ W +HL+ DG V ++ + IF G+ +R VW +LL +Y + + + ++ + K Y ++ + E+++RF +RE + +++D++RTDR+ FY E N++++ IL++Y++Y D+GY QGM+D+LAPIL + DE D+FWCF LM
Sbjct: 398 LSRCSWLEHLTADGRVEEDYKIRKSIFFAGVATEVRGEVWPFLLKYYSFRSTSHEREQLRQHKRREYADVQLARYARTHEEQERF--WREVQYTVDRDVVRTDRSHPFYQGEDNPNVEIMSGHRQILLNYAVYRPDVGYTQGMSDLLAPILAEVRDEADSFWCFVGLM 563
BLAST of TBC1 domain family member 17 vs. Ensembl Sea Lamprey
Match: TBC1D13 (TBC1 domain family member 13 [Source:HGNC Symbol;Acc:HGNC:25571]) HSP 1 Score: 78.5666 bits (192), Expect = 7.185e-16 Identity = 43/171 (25.15%), Postives = 85/171 (49.71%), Query Frame = 1
Query: 1096 EQGNLQLIYNILMSYSMYNFDLGYVQGMNDILAPILFLI----------NDEVDAFWCFTNLMDTLEPNFTQE----QLGIKKQFRQLYTLVQIFDPEFAEYLDANGCKEMLFCFRWLLVKFKRELSYENTMLLWEVLWTNYRCINFHLIFALSVLLHEKNHIMENKYGFN 1566
++ + +++ IL ++ N + YVQGMN+I+ PI + + E D F+CFTNLM + NF + Q GI + +Y+ ++ D E L K F FRWL + +E + + +W+ L+++ R +F ++ ++L+ ++ +++ + N
Sbjct: 203 QEAHWEVVERILFIFAKLNPGIAYVQGMNEIVGPIYYSFATDSSPEWREHAEADTFFCFTNLMSEIRDNFIKSLDDSQCGIGHNMQLVYSTLKERDLELYMRLQEQNIKPQFFAFRWLTLLLSQEFLLPDVLRIWDSLFSDTRRFDFLILVCSAMLMLIRDRMLQGDFAVN 373
BLAST of TBC1 domain family member 17 vs. Ensembl Sea Lamprey
Match: tbc1d2b (TBC1 domain family, member 2B [Source:ZFIN;Acc:ZDB-GENE-100922-148]) HSP 1 Score: 61.6178 bits (148), Expect = 4.636e-10 Identity = 55/236 (23.31%), Postives = 104/236 (44.07%), Query Frame = 1
Query: 829 MEKIFKGGIEMSLRSTVWKYLLNFYKWDYSLEKNHEMSRRKNDIYHKLKFQWRSIFMEQEDRFTPFRERKSIIEKDMLRT---DRALEFYSDEQGNLQLIYNILMSYSMYNFDLGYVQGMNDILAPILFLINDEVDAFWCFTNLMDTLEPN--FTQEQLGIKKQFRQLYTLVQIFDPEFAEYLDANGCKEMLFCFRWLLVKFKRELSYENTMLLWEVLWTNYRCINFHLIFALSVL 1521
++ + + G+ LRS VW++ ++E++ R ++ + + RS + P + +E D+ RT +R E S E + + +L++Y+ +N ++GY QG+N LA I + +E AFWC +++ L P +++ L + R LV P A + + +G L F W LV F + + +W+ Y +AL++L
Sbjct: 648 LKMLMRSGVPHELRSRVWRW---------AVEQHVRAIRGRHAASYYCELLERS-----HGQHNPAARQ---VELDLPRTLPNNRHFETQSSE--GIVKLRRVLLAYAWHNPEVGYCQGLNR-LAAIALIYLEEEQAFWCLVAIVECLMPPDYYSKTLLASQVDQRLFKELVTEKLPRLAAHFEQHGVDVSLITFNWFLVLFVDSVGSDMVFRIWDAFL--YEGTKVIFRYALAML 861
BLAST of TBC1 domain family member 17 vs. Ensembl Yeast
Match: GYP7 (GTPase-activating protein for yeast Rab family members; members include Ypt7p (most effective), Ypt1p, Ypt31p, and Ypt32p (in vitro); involved in vesicle mediated protein trafficking; contains a PH-like domain [Source:SGD;Acc:S000002393]) HSP 1 Score: 187.578 bits (475), Expect = 2.789e-51 Identity = 120/350 (34.29%), Postives = 182/350 (52.00%), Query Frame = 1
Query: 739 SPIQRRPPLTESEWKKHLSP-DGTV-TCVEQLMEKIFKGGIEM-SLRSTVWKYLLNFYKWDYSLEKNHEMSRRKNDIYHKLKFQWRSIFME--QEDRFTPFRERKSIIEKDMLRTDRALEFYS-----------------------------------DEQGNLQLIY--NILMSYSMYNFDLGYVQGMNDILAPILFLINDEVDAFWCFTNLMDTLEPNFTQEQLGIKKQFRQLYTLVQIFDPEFAEYLDANGCKEMLFCFRWLLVKFKRELSYENTMLLWEVLWTNYRCINFHLIFALSVLLHEKNHIMENKYGFNEILKHVNDLKLNDDLENHLCRAESLYLQLDQI 1662
+ +QR+ PLTE++W DG + V ++ + IF GG+E SLR VW +LL Y WD S ++ ++ + Y +LK W F++ ED + ++ I KD+ R DR LE + D N LI+ NIL++Y++YN +LGYVQGM D+L+PI ++ +E FWCFT+ MD +E NF ++Q GI +Q L LVQ+ PE +E+L+ + FCFR LLV FKRE E+ M +WE WT Y F L F L++L I+++ F++ILK N+L D + + RAE L+ + +++
Sbjct: 345 NALQRQFPLTEAKWNSLWDENDGRLRVTVNEVKDFIFHGGLENDSLRGKVWGFLLEIYPWDSSQDERVQIDQTLAAEYDQLKLTWSKDFLQFDDEDEEEYWNDQLFRISKDVRRCDRNLEIFQYNTIDGLPPPPQQLPANENNSTSPESANDESDDADDGVRNPHLIHLQNILITYNVYNTNLGYVQGMTDLLSPIYVIMKEEWKTFWCFTHFMDIMERNFLRDQSGIHEQMLTLVELVQLMLPELSEHLNKCDSGNLFFCFRMLLVWFKREFEMEDIMHIWENFWTFYYSSQFQLFFMLAILQKNSQAILQHLNQFDQILKFFNELNGKLDWNDLMVRAELLFKKFEKM 694
BLAST of TBC1 domain family member 17 vs. Ensembl Yeast
Match: GYP1 (Cis-golgi GTPase-activating protein (GAP) for yeast Rabs; the Rab family members are Ypt1p (in vivo) and for Ypt1p, Sec4p, Ypt7p, and Ypt51p (in vitro); involved in vesicle docking and fusion [Source:SGD;Acc:S000005596]) HSP 1 Score: 71.633 bits (174), Expect = 1.650e-13 Identity = 62/245 (25.31%), Postives = 103/245 (42.04%), Query Frame = 1
Query: 820 EQLMEKIFKGGIEMSLRSTVWKYLLNFYKWDYSLEKNHEMSRRKNDIYHKLKFQWRSIFMEQEDRFTPFRERKSIIEKDMLRTDRALEFYS--DEQGNLQLIYNILMSYSMYNFDLGYVQGMNDILAPIL--FL--------IND------------------EVDAFWCFTNLMDTLEPNFTQEQLGIKKQFRQLYTLVQIFDPEFAEYLDANGCKEMLFCFRWLLVKFKRELSYENTMLLWEV 1464
+Q + +I GI R VWK L+ + + ++ + R++ + LK F +Q R P + IE D+ RT+ + Y Q +LQ IL +++ + GYVQG+ND++ P FL I+D E D FWC T L++ + N+ Q GI +Q + L LV+ D + + + + F FRW+ RE + +W+
Sbjct: 270 QQDLRQISWNGIPKIHRPVVWKLLIGYLPVNTKRQEGF-LQRKRKEYRDSLKH----TFSDQHSRDIPTWHQ---IEIDIPRTNPHIPLYQFKSVQNSLQ---RILYLWAIRHPASGYVQGINDLVTPFFETFLTEYLPPSQIDDVEIKDPSTYMVDEQITDLEADTFWCLTKLLEQITDNYIHGQPGILRQVKNLSQLVKRIDADLYNHFQNEHVEFIQFAFRWMNCLLMREFQMGTVIRMWDT 503
BLAST of TBC1 domain family member 17 vs. Ensembl Yeast
Match: MDR1 (Cytoplasmic GTPase-activating protein; activates Ypt/Rab transport GTPases Ypt6p, Ypt31p and Sec4p; involved in recycling of internalized proteins and regulation of Golgi secretory function [Source:SGD;Acc:S000003332]) HSP 1 Score: 66.6254 bits (161), Expect = 7.443e-12 Identity = 52/182 (28.57%), Postives = 87/182 (47.80%), Query Frame = 1
Query: 1045 IEKDMLRTDRALEFYSDEQGNLQLIYNILMSYSMYNFDLGYVQGMNDILAPILFLINDEVDAFWCFTNLMDTLEPNFTQEQL-GIKKQFRQLYTLVQIFDPEFAEYLDANGCKEMLFCFRWLLVKFKRELSYENTMLLWEVLWTNYRCINFHLIFALSVLLHEKNHIME--NKYGFNEILKH 1581
IEKD+ R+ Y E+G +Q + N+L +YS N D+GY Q MN ++A L +++E AFWC NL D P + + + G R + V+ P EY+ + + + W L F + E + + ++ + N F + AL+VL + I++ + F I+KH
Sbjct: 289 IEKDLKRSLPEYSAYQTEEG-IQRLRNVLTAYSWKNPDVGYCQAMNIVVAGFLIFMSEE-QAFWCLCNLCDIYVPGYYSKTMYGTLLDQRVFESFVEDRMPVLWEYILQHDIQLSVVSLPWFLSLFFTSMPLEYAVRIMDIFFMNGSITLFQV--ALAVLKINADDILQADDDGMFIAIIKH 466
BLAST of TBC1 domain family member 17 vs. Ensembl Yeast
Match: GYP5 (GTPase-activating protein (GAP) for yeast Rab family members; involved in ER to Golgi trafficking; exhibits GAP activity toward Ypt1p that is stimulated by Gyl1p, also acts on Sec4p; interacts with Gyl1p, Rvs161p and Rvs167p; involved in recruiting Rvs167p to the bud tip during polarized growth; relocalizes from bud neck to cytoplasm upon DNA replication stress; GYP5 has a paralog, GYL1, that arose from the whole genome duplication [Source:SGD;Acc:S000006170]) HSP 1 Score: 62.003 bits (149), Expect = 1.864e-10 Identity = 61/274 (22.26%), Postives = 116/274 (42.34%), Query Frame = 1
Query: 778 WKKHLSPDGTVTCVE-QLMEKIFKGGIEMSLRSTVWKYLLNFYKWDYSLEKNHEMSRRKNDIYHKLKFQWRSIFMEQEDRFTPFRERKSIIEKDMLRTDRALEFYSDEQGNLQLIYNILMSYSMYNFDLGYVQGMNDILAPILFLINDEVDAFWCFTNLMDT--LEPNFTQEQLGIKKQFRQLYTLVQIFDPEFAEYLDANGCKEMLFCFRWLLVKFKRELSYENTMLLWEVLWTNYRCINFHLIFALSVLLHEKNHIMENKYGFNEILKHVND 1590
W + ++ TV E + +E GI +R +W+ + N SR DIY L + ++ I +D+ RT +F ++++ ++ +Y ++ YS+Y+ D+GY QGM I AP+L +E ++F LM L F G+ Q L++ P L G ++ +W L F + E + ++++++ I L FA++++L + ++ K F+E+L + D
Sbjct: 426 WTQVVNDYATVASNEPENLEAHVTNGIPPQIRGIIWQLMAN------------SKSREMEDIYETL-LDTECL-------------HEATIRRDLRRT----KFVAEDK--MESLYKVIKVYSVYDPDVGYTQGMGFIAAPLLINCENEAESFGLLVGLMKNYGLRELFLPGMPGLMLMLYQFDRLLEEHSPSLYNRLIREGISSTMYATQWFLTFFAYKFPLEFVLRIFDIVFV--EGIEVLLKFAVNLMLKNEETLV--KLRFDELLDFLKD 663
BLAST of TBC1 domain family member 17 vs. Ensembl Yeast
Match: MSB4 (GTPase-activating protein of the Ras superfamily; acts primarily on Sec4p, localizes to the bud site and bud tip; msb3 msb4 double mutation causes defects in secretion and actin organization; similar to the TBC-domain Tre2 oncogene; MSB4 has a paralog, MSB3, that arose from the whole genome duplication; human homolog USP6NL can complement yeast msb3 msb4 double null mutant [Source:SGD;Acc:S000005472]) HSP 1 Score: 47.7506 bits (112), Expect = 4.001e-6 Identity = 60/272 (22.06%), Postives = 102/272 (37.50%), Query Frame = 1
Query: 829 MEKIFKGGIEMSLRSTVWKYLLNFYKWDYSLEKNHEMSRRKNDIYHKLKFQWRSIFMEQEDRFTPFRERKSIIEKDMLRTD------RALEFYSDEQGNLQLIYNILMSYSMYNFDLGYVQGMNDILAPILFLINDEVDAFWCFTNLMDTLEPNFTQEQL-GIKKQFRQLYTLVQIFDPEF-----AEYLDANGCKE------------------MLFCFRWLLVKFKRELSYENTMLLWEVLWTNYRCINFHLIFALSVLLHEKNHIMENK 1554
+ K + GI R W Y F L+ N +Y +LK R + +D IE+D+ RT F + E ++ + +LM++S+Y+ +GY Q MN L +L L +E AFW + P + L G L ++ + PE + Y++ NG + L W + F + E T+ +W+ L+ Y +F AL +L ++ +E+K
Sbjct: 140 LSKFVRKGIPAEWRGNAWWY---FAGGQRQLDANV-------GVYDRLKSDCREGAVSGKDM--------EAIERDLYRTFPDNIHFHKESFQNGEPAIIRSLRRVLMAFSVYDKTIGYCQSMN-FLVGLLLLFMEEEKAFWMLVIITGKYLPGVYESDLEGANVDQGVLVLCIKEYLPEIWSHIESSYMNGNGSTDQISGPASGEEYLCRLPTLTLCTASWFMSCFVGVVPIETTLRIWDCLF--YEESHFLFKVALGILKLSESEFLESK 390
BLAST of TBC1 domain family member 17 vs. Ensembl Nematostella
Match: EDO50033 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RF48]) HSP 1 Score: 337.421 bits (864), Expect = 3.648e-109 Identity = 184/480 (38.33%), Postives = 281/480 (58.54%), Query Frame = 1
Query: 223 DLKSFKRSKMTVGNFNSYMIFFMKDGTSHPMMVFRDGGTKNLMDKLENYLSITKSNKERSLFLTELRREDAVFQSFESLGMFSNTKEIQASKYSQPVSNTKEKIWSGLANIGAITNQFIRSIPNDQYSHIRDLLREDAFGIPIEGHRLNTREDQESGFEIISKPVRIELPHPSPIQRRPPLTESEWKKHLSPDGTVTCVEQLMEKIFKGGIEMSLRSTVWKYLLNFYKWDYSLEKNHEMSRRKNDIYHKLKFQWRSIFMEQEDRFTPFRERKSIIEKDMLRTDRALEFYSD---EQGNLQLIYNILMSYSMYNFDLGYVQGMNDILAPILFLINDEVDAFWCFTNLMDTLEPNFTQEQLGIKKQFRQLYTLVQIFDPEFAEYLDANGCKEMLFCFRWLLVKFKRELSYENTMLLWEVLWTNYRCINFHLIFALSVLLHEKNHIMENKYGFNEILKHVNDLKLNDDLENHLCRAESLYLQL 1653
+L S +RS + SY++F +KD T+ P + F GG + ++ L+ Y+ +T+S LF+ + A+ +S + L +F AS S+ V+N + G+ + +T F ++ Q + I +D +P + ++D E FE + E P + R PL+E EW+ L G V +++L E+IF+GGI SLR VW++LL +YK+ + E + R K D Y +K QW++I +QE RF FRERK +++KD+ RTDR +Y + E N++ +Y++LM+Y MYNFDLGYVQGM+D+L+P+LFL+ +EVDAFWCF LM+ + NF + Q G+K Q QL L++ DP F YL+ + + FCFRWLL+ FKRE S+++ M LWE WT NFHLI L++L + IME ++GFNEILK+VN+L D++ L ++E+L QL
Sbjct: 5 ELNSIRRSDPKLAW--SYVVFMLKDSTTLPALHFHSGGIQAMIRTLQRYIWLTRSANNHKLFVVD-EEHKALRKSLDELQIFQEGPP-PASYLSRFVNNA---YYDGMDALSKVTRYFRDTMDIIQATGIE----QDDLALPPPA--AHYKKDAE--FEDLGARDLGEAPQ---VSREEPLSEDEWRTMLDKSGRVINIKKLHERIFRGGISPSLRGDVWRFLLGYYKYGCTFESRKTLCRAKEDEYQTMKMQWQTISAKQEKRFAEFRERKQLVDKDVTRTDRTHPYYVEKETENDNVRKLYDVLMTYCMYNFDLGYVQGMSDLLSPVLFLVENEVDAFWCFVGLMEKMAHNFDENQEGMKMQLHQLGVLLKFVDPGFYTYLEKHDSGNLYFCFRWLLICFKREFSFDDIMTLWEAFWTQNLSPNFHLIVCLAILDRHRQVIMECQFGFNEILKYVNELAYQIDVQETLIKSETLCCQL 466
BLAST of TBC1 domain family member 17 vs. Ensembl Nematostella
Match: EDO48014 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RKM9]) HSP 1 Score: 174.096 bits (440), Expect = 3.334e-48 Identity = 102/338 (30.18%), Postives = 181/338 (53.55%), Query Frame = 1
Query: 655 GHRLNTREDQESGFEIISKPVRIELPHPSPIQRRPPLTESEWKKHLSPDGTVTCVEQLMEKIFKGGIEMSLRSTVWKYLLNFYKWDYSLEKNHEMSRRKNDIYHKLKFQWRSIFMEQEDRFTPFRERKSIIEKDMLRTDRALEFYSDEQG-NLQLIYNILMSYSMYNFDLGYVQGMNDILAPILFLINDEVDAFWCFTNLMDTLEPNFTQEQLGIKKQFRQLYTLVQIFDPEF-AEYLDANGCKEMLFCFRWLLVKFKRELSYENTMLLWEVLWTNYRCINFHLIFALSVLLHEKNHIMENKYGFNEILKHVNDLKLNDDLENHLCRAESLYLQLDQI 1662
G R + E ++ F +ISK ++ R P++ WK L+ G + V +F GG+ +R WK+LL ++ + + ++ +M + K IY LK Q + M E+ ++ + ++KD+ RTDR+ +++ E N++++ +IL++Y+++N ++GY QGM+D+L+P+L + DEVDAFWCF LM+ + + + KQ L LV++ P+F A L + +MLFC RWLL+ FKRE E +L+WE W+ Y+ FHL ++++ + +++ +E+L DL + D L A L L+ ++
Sbjct: 59 GERRSQEEVRKRCFVVISK-TQVRDDCYVEEGRYDPMSAETWKTFLNSSGQIEDVANFRRAVFFGGLSPEVRKDAWKFLLGYFTYSSTSQERADMRKEKEAIY--LKAQNIRLSMTDEEYVQFWKVVQCTVDKDVPRTDRSHPYFAGEGNPNIEVMRSILLNYAIHNPEIGYSQGMSDLLSPVLAALQDEVDAFWCFAALMEASVFVTSPKDDAMDKQLAYLRELVRMMQPKFYAHLLIEDDGLDMLFCHRWLLLCFKREFYDEQVLLMWEACWSRYQTDYFHLFLCVAIMQEYGSEVLDWDMQMDEMLHFFTDLSMKMDGNKVLRTARQLLLKFRKL 393
BLAST of TBC1 domain family member 17 vs. Ensembl Nematostella
Match: EDO42591 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S184]) HSP 1 Score: 157.532 bits (397), Expect = 1.176e-42 Identity = 80/244 (32.79%), Postives = 142/244 (58.20%), Query Frame = 1
Query: 751 RRPPLTESEWKKHLSPDGTVTCVEQLMEKIFKGGIEMSLRSTVWKYLLNFYKWDYSLEKNHEMSRRKNDIYHKLKFQWRSIFMEQEDRFTPFRERKSIIEKDMLRTDRALEFY--SDEQGNLQLIYNILMSYSMYNFDLGYVQGMNDILAPILFLINDEVDAFWCFTNLMDTLEPNFTQEQLGIKKQFRQLYTLVQIFDPEFAEYLDANGCKEMLFCFRWLLVKFKRELSYENTMLLWEVLWTN 1476
++ PLT+ EW L +G + E+ +IF+ G E SLR VW +LL+ + D + ++ + K +Y L+ W + D +++KD++RTDR ++ +D+ +++ ++NIL++Y++ N D+ YVQGM+D+ +PIL ++NDE A+ CF LM ++ +F + + ++F L L+Q DP++ +YL G +M FC+RWLL+ KRE +E+ + L EV+W+
Sbjct: 138 KKGPLTKLEWPAFLDCEGRLIWREEFFSRIFQCGSEPSLRKEVWAHLLHVFPPDLTQDEREKFLLMKAQVYWHLRSDWMA-----RDPLD-IESVSHMVQKDVVRTDRVHPYFDVTDDHPHIRSLFNILVTYALANPDVSYVQGMSDLASPILVVMNDEALAYTCFCALMARMKSHFLLDSRTVTQKFDHLSMLLQKTDPQYYKYLVDIGADDMFFCYRWLLLDLKREFPFEDVLNLMEVIWST 375
BLAST of TBC1 domain family member 17 vs. Ensembl Nematostella
Match: EDO44527 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RV83]) HSP 1 Score: 135.191 bits (339), Expect = 6.233e-33 Identity = 71/209 (33.97%), Postives = 117/209 (55.98%), Query Frame = 1
Query: 1045 IEKDMLRTDRALEFYSDEQGNLQLIYNILMSYSMYNFDLGYVQGMNDILAPILFLINDEVDAFWCFTNLMDTLEPNFTQEQLGIKKQFRQLYTLVQIFDPEFAEYLDANG-CKEMLFCFRWLLVKFKRELSYENTMLLWEVLWTNYRCINFHLIF--ALSVLLHEKNHIMENKYGFNEILKHVNDLKLNDDLENHLCRAESLYLQLDQI 1662
I+KD+ R DR +++ E NL + N++ SY ++GYVQGM D++AP+L + +DE + CF LMD + NF + F + +L+Q+ DPE E+L NG FC+RW L+ FKREL Y++ +WE +W C H + AL++L ++ I++NK F +I+K N++ D + L A +L ++ ++
Sbjct: 759 IDKDVQRCDRNYWYFTQE--NLLKLRNVISSYVWTTLNVGYVQGMCDLVAPLLVIFDDESITYSCFVQLMDRMNNNFPHGG-AMDLHFSNMRSLIQVLDPEMFEHLQQNGDLTHFYFCYRWFLLDFKRELLYDDVFKVWETIWAARHCTTDHFVLFIALALLQFYRDIILDNKMDFTDIIKFFNEMAERHDAKAALEMARTLITKVQEL 964 HSP 2 Score: 53.1434 bits (126), Expect = 3.187e-7 Identity = 29/77 (37.66%), Postives = 43/77 (55.84%), Query Frame = 1
Query: 763 LTESEWKKHLSPDGTVTCVEQLMEKIFKGGIEMSLRSTVWKYLLNFYKWDYSLEKNHEMSRRKNDIYHKLKFQWRSI 993
LTE WK+ L DG+VT ++L + ++ GGI SLR VW YLL Y + + E + K + Y ++ WRS+
Sbjct: 509 LTEEAWKR-LFKDGSVTEEDRLKKYVYFGGISHSLRKEVWPYLLKHYTFGSTPESRRQTDLVKREEYQQILEDWRSV 584
BLAST of TBC1 domain family member 17 vs. Ensembl Nematostella
Match: EDO35100 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SMF5]) HSP 1 Score: 98.5969 bits (244), Expect = 1.680e-22 Identity = 56/152 (36.84%), Postives = 93/152 (61.18%), Query Frame = 1
Query: 1036 KSI--IEKDMLRTDRALEFYSDEQGNLQLIY--NILMSYSMYNFDLGYVQGMNDILAPILFLINDEVDAFWCFTNLMDTLEPNFTQEQLGIKKQFRQLYTLVQIFDPEFAEYLDANGCKEMLFCFRWLLVKFKRELSYENTMLLWEVLWTNY 1479
KSI I+KD+ RTDRA F+ QGN LI +IL++Y+ Y+ D+GY QGMNDIL+ L ++ E +A+ CF N M+ ++ +F + K + + L++ D + ++ +N ++LF RWL++ FKRE +E + L+E+L + +
Sbjct: 159 KSIRSIDKDVPRTDRAHPFFKG-QGNPNLIVLRDILITYAAYHQDVGYAQGMNDILSRFLVVLVAEDEAYSCFANYMEHVKGDFLDSTMMNKIEL--VGKLLKQMDRQLEQHFTSNDMGDLLFVHRWLVLGFKREFCFEEALKLFEILSSQH 307
BLAST of TBC1 domain family member 17 vs. Ensembl Medaka
Match: tbc1d17 (TBC1 domain family member 17 [Source:NCBI gene;Acc:101163817]) HSP 1 Score: 330.487 bits (846), Expect = 2.803e-104 Identity = 202/592 (34.12%), Postives = 317/592 (53.55%), Query Frame = 1
Query: 4 DIGIIYENQSVYILHFDNFSKEYDKELDGTLSLIEH--------NFRRPNGKIANERFITWKPNIKGE------------------LVKTVRPI----------SIDLEDLKSFKRSKMTVGNFNSYMIFFMKDGTSHPMMVFRDGGTKNLMDKLENYLSITKSNKERSLFLTELRREDAVFQSFESLGMFSNTKEIQASKYSQ-PVSNTKEKIWSGLANIGAITNQFIRSI-PNDQYSHIRDLLREDAFGIPIEGHRLNTREDQESGFEIISKPVRIELPHPSPIQRRPPLTESEWKKHLSPDGTVTCVEQLMEKIFKGGIEMSLRSTVWKYLLNFYKWDYSLEKNHEMSRRKNDIYHKLKFQWRSIFMEQEDRFTPFRERKSIIEKDMLRTDRALEFYS-DEQGNLQLIYNILMSYSMYNFDLGYVQGMNDILAPILFLINDEVDAFWCFTNLMDTLEPNFTQEQLGIKKQFRQLYTLVQIFDPEFAEYLDANGCKEMLFCFRWLLVKFKRELSYENTMLLWEVLWTNYRCINFHLIFALSVLLHEKNHIMENKYGFNEILKHVNDLKLNDDLENHLCRAESLYLQLDQI 1662
D +I+E + VY LH + D + G + ++E + G+ A T K GE +VK +P+ S+ L +L S +R++ ++G ++++ + G P + F GGT+ L+ + Y+ + +S + LFL R DA+ Q F+ L +F + S++ Q P + T +TN F +I P + H R + L ++ D E GFE+I+ V + P P + +P +W+ L P+G V E++ E +F+GGI SLR VWK+LL FY W + + ++ R K D Y ++K QW+S+ EQE R + R +S+IE+D+ RTDR F+S ++ L L++++LM+Y MYNFDLGYVQGM+D+LAPILF+ +EV++FWC T MD + NF + Q +K+Q QL L++ DPE ++LD+ + FCFRWLL+ FKRE S+E+ + LWEVLWT C NFHL+ A S+L ++ ++ + + FN ILKH+N+L + DL+N L +E++YLQL Q
Sbjct: 7 DYKLIFEKEGVY-LHTNAKRTNQDTSIPGFIRIVERAGIAALEWSPLPDEGRTAPAVLYTKKDGEGGEEETHFDPGYEPDWAVINTVVKDCQPVPIQEAGQWAFSLPLSELYSLRRARFSLGR--NFIVLTSRGGHPLPPLHFHRGGTRELLRAMHRYIVLDQSPVDGRLFLAYPRDSDALPQGFDKLQLFDDGGSDLVSRFIQDPYATT-------FGGFSKVTNFFRAAIRPPESSIHPRS----------AQDPSLPSQPDDEPGFELITCGVELG-PRPEATRGQP---LDKWEDFLDPEGRVKNPEKVKELVFRGGITPSLRKEVWKFLLGFYPWTSTTREREDILRVKTDEYFRMKVQWKSVSEEQEMRNSLLRGYRSLIERDVNRTDRHNTFFSGNDNPGLTLLHDVLMTYCMYNFDLGYVQGMSDLLAPILFVTQNEVESFWCLTGFMDLVHHNFEESQEAMKQQLLQLRILLKALDPELCDFLDSQDSGSLCFCFRWLLIWFKREFSFEDILTLWEVLWTCLPCENFHLVIACSILQSQRGELIGSNHDFNTILKHINELTMKLDLQNILRDSEAIYLQLVQC 574
BLAST of TBC1 domain family member 17 vs. Ensembl Medaka
Match: tbc1d15 (TBC1 domain family member 15 [Source:NCBI gene;Acc:101173461]) HSP 1 Score: 327.791 bits (839), Expect = 3.738e-103 Identity = 199/556 (35.79%), Postives = 305/556 (54.86%), Query Frame = 1
Query: 166 PNIKGEL----VKTVRPISIDLEDLKSFKRSKMTVGNFN-SYMIFFMKDG-TSHPMMVFRDGGTKNLMDKLENYLSITKSNKERSLFLTELRREDAVFQSFESLGMFSNTKEIQASKYSQPVSNTKEKIWSGLANIGAITNQFIRSIPNDQYSHIRDLLR-EDAFGIPIEGHRLNTREDQESGFEIISKPVRIELPHPSPIQRRPPLTESEWKKHLSPDGTVTCVEQLMEKIFKGGIEMSLRSTVWKYLLNFYKWDYSLEKNHEMSRRKNDIYHKLKFQWRSIFMEQEDRFTPFRERKSIIEKDMLRTDRALEFYSD-EQGNLQLIYNILMSYSMYNFDLGYVQGMNDILAPILFLINDEVDAFWCFTNLMDTLEPNFTQEQLGIKKQFRQLYTLVQIFDPEFAEYLDANGCKEMLFCFRWLLVKFKRELSYENTMLLWEVLWTNYRCINFHLIFALSVLLHEKNHIMENKYGFNEILKHVNDLKLNDDLENHLCRAESLYLQLDQIWCQISEETRDILDFRLSNHSVSNIVAVQ----------SGKAVADNPID 1779
PN G L ++ S+ + DL+S +TV + +++I +K+ T P + F GG++ +D L + +T+S + S L + A+ QSFE+L + N I + V+ L + +TN ++ + R + G I G +N +E E GFE+I+ R +L + R PL+ +W L +G V V + +FKGG+ ++R VWK LL + W +LE+ + R K D Y ++K QW+S+ EQE R + R+ +S+IEKD+ RTDR FY + L L+++ILM+Y MY+FDLGYVQGM+D+L+PIL+++ +EVDAFWCF ++MD + NF ++ G+K Q QL TL+++ DP F YL+ + FCFRWLL++FKRE S+++ + LWEVLWT C NFHL+ ++L EK IME +GFNEILKH+N+L + D+E L +AE L+LQ+ + +D+ SV+ I+ +Q SG AVA P D
Sbjct: 108 PNGDGSLNHSHERSRWAFSVSISDLRS-----ITVKDEGWTFLILQLKESSTPLPPLHFHQGGSREFLDNLRRFALLTESADDGSCLLVSTPNK-ALSQSFENL-LEDNLGVIHKFRQDPYVAT--------LGSFSKVTNYIYDALRGAEEQQQRPPEEVAELLGEVIPGLEINQQE--EPGFEVIT---RTDLGQRPQVSRWEPLSAEDWTNQLDAEGRVLDVAHVKHAVFKGGLCHAVRKEVWKCLLGYSPWSSTLEERKLLQRNKTDEYFRMKLQWKSVSEEQERRNSRLRDYRSLIEKDVNRTDRTNRFYEGIDNPGLALLHDILMTYCMYDFDLGYVQGMSDLLSPILYVMENEVDAFWCFVSVMDQMHQNFEEQMQGMKTQLIQLGTLLRLLDPTFWNYLEVQESGYLYFCFRWLLIRFKREFSFQDVLRLWEVLWTGLPCQNFHLLVCCAILDSEKQKIMEENFGFNEILKHINELSMKLDIEEILQKAEGLFLQM--------KSCKDL------PRSVNTILGLQEQCRESDSSDSGSAVAHRPAD 629
BLAST of TBC1 domain family member 17 vs. Ensembl Medaka
Match: tbc1d15 (TBC1 domain family member 15 [Source:NCBI gene;Acc:101173461]) HSP 1 Score: 313.923 bits (803), Expect = 9.360e-93 Identity = 193/508 (37.99%), Postives = 288/508 (56.69%), Query Frame = 1
Query: 208 SIDLEDLKSFKRSKMTVGNFN-SYMIFFMKDG-TSHPMMVFRDGGTKNLMDKLENYLSITKSNKERSLFLTELRREDAVFQSFESLGMFSNTKEIQASKYSQ-PVSNTKEKIWSGLANIGAITNQFIRSIPNDQYSHIRDLLR-------------EDAFGIPIEGHRLNTREDQESGFEIISKPVRIELPHPSPIQRRPPLTESEWKKHLSPDGTVTCVEQLMEKIFKGGIEMSLRSTVWKYLLNFYKWDYSLEKNHEMSRRKNDIYHKLKFQWRSIFMEQEDRFTPFRERKSIIEKDMLRTDRALEFYS--DEQGNLQLIYNILMSYSMYNFDLGYVQGMNDILAPILFLINDEVDAFWCFTNLMDTLEPNFTQEQLGIKKQFRQLYTLVQIFDPEFAEYLDANGCKEMLFCFRWLLVKFKRELSYENTMLLWEVLWTNYRCINFHLIFALSVLLHEKNHIMENKYGFNEILKHVNDLKLNDDLENHLCRAESLYLQLDQIWCQIS 1677
S+ + DL+S +TV + +++I +K+ T P + F GG++ +D L + +T+S + S L A+ QSFE+L + N I K+ Q P T L + +TN +I D LR + G I G +N +E E GFE+I+ R +L + R PL+ +W L +G V V + +FKGG+ ++R VWK LL + W +LE+ + R K D Y ++K QW+S+ EQE R + R+ +S+IEKD+ RTDR FY D G L L+++ILM+Y MY+FDLGYVQGM+D+L+PIL+++ +EVDAFWCF ++MD + NF ++ G+K Q QL TL+++ DP F YL+ + FCFRWLL++FKRE S+++ + LWEVLWT C NFHL+ ++L EK IME +GFNEILKH+N+L + D+E L +AE L+LQ+ C++S
Sbjct: 126 SVSISDLRS-----ITVKDEGWTFLILQLKESSTPLPPLHFHQGGSREFLDNLRRFALLTESADDGSCLLVS-TPNKALSQSFENL-LEDNLGVIH--KFRQDPYVAT-------LGSFSKVTN------------YIYDALRGAEEQQQRPPEEVAELLGEVIPGLEINQQE--EPGFEVIT---RTDLGQRPQVSRWEPLSAEDWTNQLDAEGRVLDVAHVKHAVFKGGLCHAVRKEVWKCLLGYSPWSSTLEERKLLQRNKTDEYFRMKLQWKSVSEEQERRNSRLRDYRSLIEKDVNRTDRTNRFYEGIDNPG-LALLHDILMTYCMYDFDLGYVQGMSDLLSPILYVMENEVDAFWCFVSVMDQMHQNFEEQMQGMKTQLIQLGTLLRLLDPTFWNYLEVQESGYLYFCFRWLLIRFKREFSFQDVLRLWEVLWTGLPCQNFHLLVCCAILDSEKQKIMEENFGFNEILKHINELSMKLDIEEILQKAEGLFLQMKS--CKVS 597
BLAST of TBC1 domain family member 17 vs. Ensembl Medaka
Match: tbc1d16 (TBC1 domain family member 16 [Source:NCBI gene;Acc:101159919]) HSP 1 Score: 173.326 bits (438), Expect = 1.965e-45 Identity = 97/307 (31.60%), Postives = 175/307 (57.00%), Query Frame = 1
Query: 772 SEWKKHLSPDGTVTCVEQLMEKIFKGGIEMSLRSTVWKYLLNFYKWDYSLEKNHEMSRRKNDIYHKLKFQWRSIFMEQEDRFTPFRERKSIIEKDMLRTDRALEFYSDEQG-NLQLIYNILMSYSMYNFDLGYVQGMNDILAPILFLINDEVDAFWCFTNLMDTLEPNFTQEQLGIKKQFRQLYTLVQIFDPEFAEYLDANG--CKEMLFCFRWLLVKFKRELSYENTMLLWEVLWTNYRCINFHLIFALSVLLHEKNHIMENKYGFNEILKHVNDLKLNDDLENHLCRAESLYLQ---LDQIWCQI 1674
+ W HL+ DG V +L + IF GGI+ S+R VW +LL++Y +D + ++ +K Y+ + Q R + M E+ +R+ + ++KD++RTDR+ +F+ E N++++ IL++Y+++N D+GY QGM+D++AP+L I DE D FWCF LM+ + +++Q L L+++ P F ++L G ++LFC RW+L+ FKRE + +WE W +Y+ FHL +++++ + E + +++L H ++L ++ + E L +A SL Q L +I C +
Sbjct: 366 TSWLHHLNQDGQVEEEYKLRKAIFFGGIDPSIRGEVWPFLLHYYSYDSTSQEREAWRLQKRTEYYDI--QQRRLSMSPEEHSEFWRKVQFTVDKDVVRTDRSNQFFRGENNQNVEIMRRILLNYAVFNPDMGYCQGMSDLVAPLLTEIQDESDTFWCFVGLMENTIFISSPRDEDMERQLMYLRELLRLMLPRFHQHLTRLGEDGLQLLFCHRWILLCFKREFPDTEALRMWEACWAHYQTDYFHLFLCVAIIVLYGEDVTEQQLATDQMLLHFSNLSMHMNGELVLRKARSLLYQFRLLPRIPCSL 670
BLAST of TBC1 domain family member 17 vs. Ensembl Medaka
Match: tbc1d25 (TBC1 domain family member 25 [Source:NCBI gene;Acc:101161299]) HSP 1 Score: 167.933 bits (424), Expect = 2.103e-43 Identity = 87/243 (35.80%), Postives = 151/243 (62.14%), Query Frame = 1
Query: 754 RPPLTESEWKKHLSPDGTVTCVEQLMEKIFKGGIEMSLRSTVWKYLLNFYKWDYSLEKNHEMSRRKNDIYHKLKFQWRSIFMEQEDRFTPFRERKSIIEKDMLRTDRALEFY--SDEQGNLQLIYNILMSYSMYNFDLGYVQGMNDILAPILFLINDEVDAFWCFTNLMDTLEPNFTQEQLGIKKQFRQLYTLVQIFDPEFAEYLDANGCKEMLFCFRWLLVKFKRELSYENTMLLWEVLWTN 1476
+PPL++SE+ +L+ G +T E+L +I+ GG+E SLR VW+YLLN Y + ++ + +RK Y +LK +W + + + F R +++ KD+LRTDRA +Y S++ +L + ++L +Y++ + + Y QGM+DI +PIL ++++E AF CF +M LE NF + + +F+ L L+Q DPEF YL + G ++ FC+RWLL++ KRE ++++ + + EV W++
Sbjct: 170 KPPLSDSEFHSYLNGQGQLTRPEELRLRIYHGGVEPSLRKVVWRYLLNVYPDGLTGQERMDYMKRKTREYDQLKREWPARVSQDDLEFI----RGNVL-KDVLRTDRAHAYYAGSEDSPHLTALTDLLTTYAITHPQISYCQGMSDIASPILAVMDNEAHAFICFCGIMKRLEGNFRPDGQLMSIKFQHLKLLLQYSDPEFYSYLVSRGADDLFFCYRWLLLELKREFAFDDALRMLEVTWSS 407
BLAST of TBC1 domain family member 17 vs. Planmine SMEST
Match: SMESG000030372.1 (SMESG000030372.1) HSP 1 Score: 1281.54 bits (3315), Expect = 0.000e+0 Identity = 617/617 (100.00%), Postives = 617/617 (100.00%), Query Frame = 1
Query: 1 MDIGIIYENQSVYILHFDNFSKEYDKELDGTLSLIEHNFRRPNGKIANERFITWKPNIKGELVKTVRPISIDLEDLKSFKRSKMTVGNFNSYMIFFMKDGTSHPMMVFRDGGTKNLMDKLENYLSITKSNKERSLFLTELRREDAVFQSFESLGMFSNTKEIQASKYSQPVSNTKEKIWSGLANIGAITNQFIRSIPNDQYSHIRDLLREDAFGIPIEGHRLNTREDQESGFEIISKPVRIELPHPSPIQRRPPLTESEWKKHLSPDGTVTCVEQLMEKIFKGGIEMSLRSTVWKYLLNFYKWDYSLEKNHEMSRRKNDIYHKLKFQWRSIFMEQEDRFTPFRERKSIIEKDMLRTDRALEFYSDEQGNLQLIYNILMSYSMYNFDLGYVQGMNDILAPILFLINDEVDAFWCFTNLMDTLEPNFTQEQLGIKKQFRQLYTLVQIFDPEFAEYLDANGCKEMLFCFRWLLVKFKRELSYENTMLLWEVLWTNYRCINFHLIFALSVLLHEKNHIMENKYGFNEILKHVNDLKLNDDLENHLCRAESLYLQLDQIWCQISEETRDILDFRLSNHSVSNIVAVQSGKAVADNPIDTMKQGFKSANFELDCRNNCDAILH 1851
MDIGIIYENQSVYILHFDNFSKEYDKELDGTLSLIEHNFRRPNGKIANERFITWKPNIKGELVKTVRPISIDLEDLKSFKRSKMTVGNFNSYMIFFMKDGTSHPMMVFRDGGTKNLMDKLENYLSITKSNKERSLFLTELRREDAVFQSFESLGMFSNTKEIQASKYSQPVSNTKEKIWSGLANIGAITNQFIRSIPNDQYSHIRDLLREDAFGIPIEGHRLNTREDQESGFEIISKPVRIELPHPSPIQRRPPLTESEWKKHLSPDGTVTCVEQLMEKIFKGGIEMSLRSTVWKYLLNFYKWDYSLEKNHEMSRRKNDIYHKLKFQWRSIFMEQEDRFTPFRERKSIIEKDMLRTDRALEFYSDEQGNLQLIYNILMSYSMYNFDLGYVQGMNDILAPILFLINDEVDAFWCFTNLMDTLEPNFTQEQLGIKKQFRQLYTLVQIFDPEFAEYLDANGCKEMLFCFRWLLVKFKRELSYENTMLLWEVLWTNYRCINFHLIFALSVLLHEKNHIMENKYGFNEILKHVNDLKLNDDLENHLCRAESLYLQLDQIWCQISEETRDILDFRLSNHSVSNIVAVQSGKAVADNPIDTMKQGFKSANFELDCRNNCDAILH
Sbjct: 1 MDIGIIYENQSVYILHFDNFSKEYDKELDGTLSLIEHNFRRPNGKIANERFITWKPNIKGELVKTVRPISIDLEDLKSFKRSKMTVGNFNSYMIFFMKDGTSHPMMVFRDGGTKNLMDKLENYLSITKSNKERSLFLTELRREDAVFQSFESLGMFSNTKEIQASKYSQPVSNTKEKIWSGLANIGAITNQFIRSIPNDQYSHIRDLLREDAFGIPIEGHRLNTREDQESGFEIISKPVRIELPHPSPIQRRPPLTESEWKKHLSPDGTVTCVEQLMEKIFKGGIEMSLRSTVWKYLLNFYKWDYSLEKNHEMSRRKNDIYHKLKFQWRSIFMEQEDRFTPFRERKSIIEKDMLRTDRALEFYSDEQGNLQLIYNILMSYSMYNFDLGYVQGMNDILAPILFLINDEVDAFWCFTNLMDTLEPNFTQEQLGIKKQFRQLYTLVQIFDPEFAEYLDANGCKEMLFCFRWLLVKFKRELSYENTMLLWEVLWTNYRCINFHLIFALSVLLHEKNHIMENKYGFNEILKHVNDLKLNDDLENHLCRAESLYLQLDQIWCQISEETRDILDFRLSNHSVSNIVAVQSGKAVADNPIDTMKQGFKSANFELDCRNNCDAILH 617
BLAST of TBC1 domain family member 17 vs. Planmine SMEST
Match: SMESG000030372.1 (SMESG000030372.1) HSP 1 Score: 1278.85 bits (3308), Expect = 0.000e+0 Identity = 616/617 (99.84%), Postives = 617/617 (100.00%), Query Frame = 1
Query: 1 MDIGIIYENQSVYILHFDNFSKEYDKELDGTLSLIEHNFRRPNGKIANERFITWKPNIKGELVKTVRPISIDLEDLKSFKRSKMTVGNFNSYMIFFMKDGTSHPMMVFRDGGTKNLMDKLENYLSITKSNKERSLFLTELRREDAVFQSFESLGMFSNTKEIQASKYSQPVSNTKEKIWSGLANIGAITNQFIRSIPNDQYSHIRDLLREDAFGIPIEGHRLNTREDQESGFEIISKPVRIELPHPSPIQRRPPLTESEWKKHLSPDGTVTCVEQLMEKIFKGGIEMSLRSTVWKYLLNFYKWDYSLEKNHEMSRRKNDIYHKLKFQWRSIFMEQEDRFTPFRERKSIIEKDMLRTDRALEFYSDEQGNLQLIYNILMSYSMYNFDLGYVQGMNDILAPILFLINDEVDAFWCFTNLMDTLEPNFTQEQLGIKKQFRQLYTLVQIFDPEFAEYLDANGCKEMLFCFRWLLVKFKRELSYENTMLLWEVLWTNYRCINFHLIFALSVLLHEKNHIMENKYGFNEILKHVNDLKLNDDLENHLCRAESLYLQLDQIWCQISEETRDILDFRLSNHSVSNIVAVQSGKAVADNPIDTMKQGFKSANFELDCRNNCDAILH 1851
+DIGIIYENQSVYILHFDNFSKEYDKELDGTLSLIEHNFRRPNGKIANERFITWKPNIKGELVKTVRPISIDLEDLKSFKRSKMTVGNFNSYMIFFMKDGTSHPMMVFRDGGTKNLMDKLENYLSITKSNKERSLFLTELRREDAVFQSFESLGMFSNTKEIQASKYSQPVSNTKEKIWSGLANIGAITNQFIRSIPNDQYSHIRDLLREDAFGIPIEGHRLNTREDQESGFEIISKPVRIELPHPSPIQRRPPLTESEWKKHLSPDGTVTCVEQLMEKIFKGGIEMSLRSTVWKYLLNFYKWDYSLEKNHEMSRRKNDIYHKLKFQWRSIFMEQEDRFTPFRERKSIIEKDMLRTDRALEFYSDEQGNLQLIYNILMSYSMYNFDLGYVQGMNDILAPILFLINDEVDAFWCFTNLMDTLEPNFTQEQLGIKKQFRQLYTLVQIFDPEFAEYLDANGCKEMLFCFRWLLVKFKRELSYENTMLLWEVLWTNYRCINFHLIFALSVLLHEKNHIMENKYGFNEILKHVNDLKLNDDLENHLCRAESLYLQLDQIWCQISEETRDILDFRLSNHSVSNIVAVQSGKAVADNPIDTMKQGFKSANFELDCRNNCDAILH
Sbjct: 18 IDIGIIYENQSVYILHFDNFSKEYDKELDGTLSLIEHNFRRPNGKIANERFITWKPNIKGELVKTVRPISIDLEDLKSFKRSKMTVGNFNSYMIFFMKDGTSHPMMVFRDGGTKNLMDKLENYLSITKSNKERSLFLTELRREDAVFQSFESLGMFSNTKEIQASKYSQPVSNTKEKIWSGLANIGAITNQFIRSIPNDQYSHIRDLLREDAFGIPIEGHRLNTREDQESGFEIISKPVRIELPHPSPIQRRPPLTESEWKKHLSPDGTVTCVEQLMEKIFKGGIEMSLRSTVWKYLLNFYKWDYSLEKNHEMSRRKNDIYHKLKFQWRSIFMEQEDRFTPFRERKSIIEKDMLRTDRALEFYSDEQGNLQLIYNILMSYSMYNFDLGYVQGMNDILAPILFLINDEVDAFWCFTNLMDTLEPNFTQEQLGIKKQFRQLYTLVQIFDPEFAEYLDANGCKEMLFCFRWLLVKFKRELSYENTMLLWEVLWTNYRCINFHLIFALSVLLHEKNHIMENKYGFNEILKHVNDLKLNDDLENHLCRAESLYLQLDQIWCQISEETRDILDFRLSNHSVSNIVAVQSGKAVADNPIDTMKQGFKSANFELDCRNNCDAILH 634
BLAST of TBC1 domain family member 17 vs. Planmine SMEST
Match: SMESG000062665.1 (SMESG000062665.1) HSP 1 Score: 131.724 bits (330), Expect = 1.044e-31 Identity = 80/292 (27.40%), Postives = 145/292 (49.66%), Query Frame = 1
Query: 754 RPPLTESEWKKHLSPDGTVTCVEQLMEKIFKGGIEMSLRSTVWKYLLNFYKWDYSLEKNHEMSRRKNDIYHKLKFQWRSIFMEQEDRFTPFRERK-SIIEKDMLRTDRALEFYSDE--QGNLQLIYNILMSYSMYNFDLGYVQGMNDILAPILFLINDEVDAFWCFTNLMDTLEPNFTQ--------------------EQLGIKKQFRQLYTLVQIFDPEFAEYLDANGCKEMLFCFRWLLVKFKRELSYENTMLLWEVLWTNYRCINFHLIFALSVLLHEKNHIMENKYG 1560
+PP+++ E++ ++ G + ++ + ++ GG+E SLR W+ LL+ Y + + + K+ Y LK W+ F +E + T + +++ D++RTDR+L FYS E Q ++ +++IL +Y +Y+ +GY QGM+D+ +P+LF+ +E A+ CF +LM + NF E GI + + L+ L+ DP A +L F RW+L++ KRE + +++ L EV W + + L E ++EN YG
Sbjct: 187 KPPMSDIEFRNYMDNIGRIVQPDEFKQSVYLGGLEPSLRKVGWRLLLDIYPVGLTGRERLNLLEVKSKHYRSLKHSWKQKF--KEGKLTEQEMAQIALVSVDVIRTDRSLNFYSGEKNQQHVAQLFDILATYCIYHPSIGYYQGMSDLASPLLFVQCEEAVAYLCFCSLMRRVSCNFVSGSNSQNTSSSLNGEKSQNNTEYNGILGKLQNLHDLLVYLDPHLAYFLREKYLGNFFFAHRWILLEMKREFPFLDSLRLLEVQWASLPSSKY-----LGTSSSEGVSLVENGYG 471
BLAST of TBC1 domain family member 17 vs. Planmine SMEST
Match: SMESG000062665.1 (SMESG000062665.1) HSP 1 Score: 131.339 bits (329), Expect = 1.163e-31 Identity = 80/292 (27.40%), Postives = 145/292 (49.66%), Query Frame = 1
Query: 754 RPPLTESEWKKHLSPDGTVTCVEQLMEKIFKGGIEMSLRSTVWKYLLNFYKWDYSLEKNHEMSRRKNDIYHKLKFQWRSIFMEQEDRFTPFRERK-SIIEKDMLRTDRALEFYSDE--QGNLQLIYNILMSYSMYNFDLGYVQGMNDILAPILFLINDEVDAFWCFTNLMDTLEPNFTQ--------------------EQLGIKKQFRQLYTLVQIFDPEFAEYLDANGCKEMLFCFRWLLVKFKRELSYENTMLLWEVLWTNYRCINFHLIFALSVLLHEKNHIMENKYG 1560
+PP+++ E++ ++ G + ++ + ++ GG+E SLR W+ LL+ Y + + + K+ Y LK W+ F +E + T + +++ D++RTDR+L FYS E Q ++ +++IL +Y +Y+ +GY QGM+D+ +P+LF+ +E A+ CF +LM + NF E GI + + L+ L+ DP A +L F RW+L++ KRE + +++ L EV W + + L E ++EN YG
Sbjct: 190 KPPMSDIEFRNYMDNIGRIVQPDEFKQSVYLGGLEPSLRKVGWRLLLDIYPVGLTGRERLNLLEVKSKHYRSLKHSWKQKF--KEGKLTEQEMAQIALVSVDVIRTDRSLNFYSGEKNQQHVAQLFDILATYCIYHPSIGYYQGMSDLASPLLFVQCEEAVAYLCFCSLMRRVSCNFVSGSNSQNTSSSLNGEKSQNNTEYNGILGKLQNLHDLLVYLDPHLAYFLREKYLGNFFFAHRWILLEMKREFPFLDSLRLLEVQWASLPSSKY-----LGTSSSEGVSLVENGYG 474
BLAST of TBC1 domain family member 17 vs. Planmine SMEST
Match: SMESG000062665.1 (SMESG000062665.1) HSP 1 Score: 131.339 bits (329), Expect = 1.371e-31 Identity = 80/292 (27.40%), Postives = 145/292 (49.66%), Query Frame = 1
Query: 754 RPPLTESEWKKHLSPDGTVTCVEQLMEKIFKGGIEMSLRSTVWKYLLNFYKWDYSLEKNHEMSRRKNDIYHKLKFQWRSIFMEQEDRFTPFRERK-SIIEKDMLRTDRALEFYSDE--QGNLQLIYNILMSYSMYNFDLGYVQGMNDILAPILFLINDEVDAFWCFTNLMDTLEPNFTQ--------------------EQLGIKKQFRQLYTLVQIFDPEFAEYLDANGCKEMLFCFRWLLVKFKRELSYENTMLLWEVLWTNYRCINFHLIFALSVLLHEKNHIMENKYG 1560
+PP+++ E++ ++ G + ++ + ++ GG+E SLR W+ LL+ Y + + + K+ Y LK W+ F +E + T + +++ D++RTDR+L FYS E Q ++ +++IL +Y +Y+ +GY QGM+D+ +P+LF+ +E A+ CF +LM + NF E GI + + L+ L+ DP A +L F RW+L++ KRE + +++ L EV W + + L E ++EN YG
Sbjct: 214 KPPMSDIEFRNYMDNIGRIVQPDEFKQSVYLGGLEPSLRKVGWRLLLDIYPVGLTGRERLNLLEVKSKHYRSLKHSWKQKF--KEGKLTEQEMAQIALVSVDVIRTDRSLNFYSGEKNQQHVAQLFDILATYCIYHPSIGYYQGMSDLASPLLFVQCEEAVAYLCFCSLMRRVSCNFVSGSNSQNTSSSLNGEKSQNNTEYNGILGKLQNLHDLLVYLDPHLAYFLREKYLGNFFFAHRWILLEMKREFPFLDSLRLLEVQWASLPSSKY-----LGTSSSEGVSLVENGYG 498 The following BLAST results are available for this feature:
BLAST of TBC1 domain family member 17 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of TBC1 domain family member 17 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of TBC1 domain family member 17 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of TBC1 domain family member 17 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of TBC1 domain family member 17 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of TBC1 domain family member 17 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of TBC1 domain family member 17 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of TBC1 domain family member 17 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of TBC1 domain family member 17 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of TBC1 domain family member 17 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of TBC1 domain family member 17 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 5
BLAST of TBC1 domain family member 17 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of TBC1 domain family member 17 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of TBC1 domain family member 17 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30009767 ID=SMED30009767|Name=TBC1 domain family member 17|organism=Schmidtea mediterranea sexual|type=transcript|length=1934bpback to top protein sequence of SMED30009767-orf-1 >SMED30009767-orf-1 ID=SMED30009767-orf-1|Name=SMED30009767-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=618bp MDIGIIYENQSVYILHFDNFSKEYDKELDGTLSLIEHNFRRPNGKIANERback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
|
