TNF receptor-associated factor 4
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30009756 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 6
Homology
BLAST of TNF receptor-associated factor 4 vs. Ensembl Human
Match: TRAF4 (TNF receptor associated factor 4 [Source:HGNC Symbol;Acc:HGNC:12034]) HSP 1 Score: 226.483 bits (576), Expect = 1.020e-66 Identity = 136/479 (28.39%), Postives = 214/479 (44.68%), Query Frame = 1
Query: 502 DVIFIDPLEKKYACVVCDQVLRYPVQFDECGHHCCSSCLPELMRVAP-RCPIDQCHIERDKVYVDKEFQKEIDNLGVRCSFYQKGCIWTGVLK---------------------------ELSNHLES---------------------------CLHRMITCPNNCNVEFEIRFLEKHKQDDCPKRIIQCQFCEASLIAEVEANHLKVCNKFPIPCPNGCKKKEILRENLAEHLESKCVKQEQDCPFSEYGCDFKGKKKRVREHLNDDFVSHLTLMCEAIKENTRIVEEQSKIITQYQTEVGTFEKRIESLEKLYGPQLIWKIDNYQEKFNEAKTGKKTTIFSAPFMTSRFGYKMALSVCLYGDGKARGKHFSLFICICKGDYDSLLLWPFSHRITFTLIDQCQDPEARK--NVVYTVKPNTCKEN--APFLGRPTTDRNA-SFGAQKFVELDVLNTLDYIRDDAIFIKAQVDCDEMI 1758
D F++ +++ C +C + +R PVQ CGH C +CL E + +CP DQ ++ K+Y D E + ++ L +RC ++GC W+G L+ +L HL+ C + C N C R L +H +CPKR C +C + + +H C + P+ CPN C + RE+L HL+ C CPF + GC + K + H+ + HL +MC ++++ + E+ + +E L LIWKI +Y + EAK FS F T ++GYK+ +S L G+G G H SL+I + G +D+LL WPF+ R+TF+L+DQ DP K +V T P+ +N P R + D ++ FG KF+ + +Y+RDDA+FI+A V+ I
Sbjct: 5 DYKFLEKPKRRLLCPLCGKPMREPVQVSTCGHRFCDTCLQEFLSEGVFKCPEDQLPLDYAKIYPDPELEVQVLGLPIRCIHSEEGCRWSGPLRHLQGHLNTCSFNVIPCPNRCPMKLSRRDLPAHLQHDCPKRRLKCEFCGCDFSGEAYESHEGMCPQESVYCENKCGARMMRRLLAQHATSECPKRTQPCTYCTKEFVFDTIQSHQYQCPRLPVACPNQCGVGTVAREDLPGHLKDSCNTALVLCPFKDSGCKHRCPKLAMARHVEESVKPHLAMMC--------------ALVSRQRQELQELRRELEELSVGSDGVLIWKIGSYGRRLQEAKAKPNLECFSPAFYTHKYGYKLQVSAFLNGNGSGEGTHLSLYIRVLPGAFDNLLEWPFARRVTFSLLDQ-SDPGLAKPQHVTETFHPDPNWKNFQKPGTWRGSLDESSLGFGYPKFISHQDIRKRNYVRDDAVFIRAAVELPRKI 468
BLAST of TNF receptor-associated factor 4 vs. Ensembl Human
Match: TRAF2 (TNF receptor associated factor 2 [Source:HGNC Symbol;Acc:HGNC:12032]) HSP 1 Score: 201.83 bits (512), Expect = 3.521e-57 Identity = 153/484 (31.61%), Postives = 221/484 (45.66%), Query Frame = 1
Query: 523 LEKKYACVVCDQVLRYPVQFDECGHHCCSSCLPELMRVAPRCPIDQCH----------IERDKVYVDKEFQKEIDNLGVRCSFYQKGCIWTGVLKEL-SNHLESCLHRMITCPNNCNVEFEIRFLEKHKQDDCPKRIIQCQFCEASLI-AEVEANHLKVCNKFPIPCPNGCKKKEILRENLAEHLESKCVKQEQDCPFSEYGC--DFKGKKKR------VREHL----------------NDDFVSHLTLMCEAIKENTRIVE--------------------------EQSKI------ITQYQTEVGTFEKRIESLEK--------LYGPQLIWKIDNYQEKFNEAKTGKKTTIFSAPFMTSRFGYKMALSVCLYGDGKARGKHFSLFICICKGDYDSLLLWPFSHRITFTLIDQCQDPEARKNVVYTVKPNTCKENAPFLGRPTTDRNASFGAQKFVELDVLNTLD-YIRDDAIFIKAQVD 1743
LE KY C C VLR P Q +CGH CS CL ++ P+ H +E + D ++E+++L C GC W G LKE S H C + CP C + E+H + +CP+R + C+ C A A+V+A+H +VC KFP+ C +GC KK+I RE +H+++ C K C F GC +G+K++ +REHL S L CE++++ T E +Q KI + Q + +G + + LE+ Y IWKI ++ K EA G+ IFS F TSR+GYKM L + L GDG RG H SLF + KG D+LL WPF+ ++T L+DQ R++V+ +P+ + RP D N + G F + + + Y+RDDAIFIKA VD
Sbjct: 28 LEAKYLCSACRNVLRRPFQ-AQCGHRYCSFCLASILSSGPQNCAACVHEGIYEEGISILESSSAFPDNAARREVESLPAVCP--SDGCTWKGTLKEYESCHEGRCPLMLTECPA-CKGLVRLGEKERHLEHECPERSLSCRHCRAPCCGADVKAHH-EVCPKFPLTC-DGCGKKKIPREKFQDHVKT-CGKCRVPCRFHAIGCLETVEGEKQQEHEVQWLREHLAMLLSSVLEAKPLLGDQSHAGSELLQRCESLEKKTATFENIVCVLNREVERVAMTAEACSRQHRLDQDKIEALSSKVQQLERSIGLKDLAMADLEQKVLEMEASTYDGVFIWKISDFARKRQEAVAGRIPAIFSPAFYTSRYGYKMCLRIYLNGDGTGRGTHLSLFFVVMKGPNDALLRWPFNQKVTLMLLDQ----NNREHVIDAFRPDVTSSS---FQRPVNDMNIASGCPLFCPVSKMEAKNSYVRDDAIFIKAIVD 497
BLAST of TNF receptor-associated factor 4 vs. Ensembl Human
Match: TRAF4 (TNF receptor associated factor 4 [Source:HGNC Symbol;Acc:HGNC:12034]) HSP 1 Score: 189.504 bits (480), Expect = 3.086e-53 Identity = 111/419 (26.49%), Postives = 176/419 (42.00%), Query Frame = 1
Query: 502 DVIFIDPLEKKYACVVCDQVLRYPVQFDECGHHCCSSCLPELMRVAP-RCPIDQCHIERDKVYVDKEFQKEIDNLGVRCSFYQKGCIWTGVLK---------------------------ELSNHLES---------------------------CLHRMITCPNNCNVEFEIRFLEKHKQDDCPKRIIQCQFCEASLIAEVEANHLKVCNKFPIPCPNGCKKKEILRENLAEHLESKCVKQEQDCPFSEYGCDFKGKKKRVREHLNDDFVSHLTLMCEAIKENTRIVEEQSKIITQYQTEVGTFEKRIESLEKLYGPQLIWKIDNYQEKFNEAKTGKKTTIFSAPFMTSRFGYKMALSVCLYGDGKARGKHFSLFICICKGDYDSLLLWPFSHRITFTLIDQCQDPEARKNVVYTVKP 1593
D F++ +++ C +C + +R PVQ CGH C +CL E + +CP DQ ++ K+Y D E + ++ L +RC ++GC W+G L+ +L HL+ C + C N C R L +H +CPKR C +C + + +H C + P+ CPN C + RE+L HL+ C CPF + GC + K + H+ + HL +MC ++++ + E+ + +E L LIWKI +Y + EAK FS F T ++GYK+ +S L G+G G H SL+I + G +D+LL WPF+ R + + P R + T P
Sbjct: 5 DYKFLEKPKRRLLCPLCGKPMREPVQVSTCGHRFCDTCLQEFLSEGVFKCPEDQLPLDYAKIYPDPELEVQVLGLPIRCIHSEEGCRWSGPLRHLQGHLNTCSFNVIPCPNRCPMKLSRRDLPAHLQHDCPKRRLKCEFCGCDFSGEAYESHEGMCPQESVYCENKCGARMMRRLLAQHATSECPKRTQPCTYCTKEFVFDTIQSHQYQCPRLPVACPNQCGVGTVAREDLPGHLKDSCNTALVLCPFKDSGCKHRCPKLAMARHVEESVKPHLAMMC--------------ALVSRQRQELQELRRELEELSVGSDGVLIWKIGSYGRRLQEAKAKPNLECFSPAFYTHKYGYKLQVSAFLNGNGSGEGTHLSLYIRVLPGAFDNLLEWPFARRGLSPFLGRADMPWCRSHSTRTEVP 409
BLAST of TNF receptor-associated factor 4 vs. Ensembl Human
Match: TRAF3 (TNF receptor associated factor 3 [Source:HGNC Symbol;Acc:HGNC:12033]) HSP 1 Score: 176.792 bits (447), Expect = 3.395e-48 Identity = 150/495 (30.30%), Postives = 229/495 (46.26%), Query Frame = 1
Query: 412 SSVSIDSVGIFHNQIKNPPIITNSNNQNDVDVI----------FIDPLEKKYACVVCDQVLRYPVQFDECGHHCCSSCLPELMRVA-PRCPIDQCHIERDKVYVDKEFQKEIDNLGVRCSFYQKGCIWTGVLKELSNHLES-CLHRMITCPN-NCNVEFEIRFLEKHKQDDCPKRIIQCQFCEAS--LIA---------EVEAN------HLKVCNKFPIPCPNGCKKKEILRENLAE--HLESKCVKQEQDC--------PFSEYGCDFKGKKKRVREHLNDDFVSHLTLMCEA--IKENTRIVEEQ----SKIITQYQTEVGTFEKRIESLEKL-YGPQLIWKIDNYQEKFNEAKTGKKTTIFSAPFMTSRFGYKMALSVCLYGDGKARGKHFSLFICICKGDYDSLLLWPFSHRITFTLIDQCQDPEARKNVVYTVKPNTCKENAPFLGRPTTDRNASFGAQKFVELDVLNTLDYIRDDAIFIKAQVDCDEM 1755
SS +DS G NPP+ +++ V F+ +E KY C C VL P Q ECGH C SC+ L+ + P+C Q I +DKV+ D ++EI L + C +GC +L L HL++ C + C +C + + L H + C R C C++ +IA VE N H ++C+ F I ++KE+LR N ++ HL+ Q + PF + + K V E L + ++ A + NT ++E Q ++++ + + + R + LE Y LIWKI +Y+ + EA GK +++S PF T FGYKM V L GDG +G H SLF I +G+YD+LL WPF ++T L+DQ +R+++ KP+ N+ +PT + N + G FV VL YI+DD IFIK VD ++
Sbjct: 3 SSKKMDSPGALQT---NPPLKLHTDRSAGTPVFVPEQGGYKEKFVKTVEDKYKCEKCHLVLCSPKQ-TECGHRFCESCMAALLSSSSPKCTACQESIVKDKVFKDNCCKREILALQIYCRNESRGCAEQLMLGHLLVHLKNDCHFEELPCVRPDCKEKVLRKDLRDHVEKACKYREATCSHCKSQVPMIALQVSLLQNESVEKNKSIQSLHNQICS-FEIEIE---RQKEMLRNNESKILHLQRVIDSQAEKLKELDKEIRPFRQNWEEADSMKSSV-ESLQNRVTELESVDKSAGQVARNTGLLESQLSRHDQMLSVHDIRLADMDLRFQVLETASYNGVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVTLMLMDQ---GSSRRHLGDAFKPDP---NSSSFKKPTGEMNIASGCPVFVAQTVLENGTYIKDDTIFIKVIVDTSDL 482
BLAST of TNF receptor-associated factor 4 vs. Ensembl Human
Match: TRAF6 (TNF receptor associated factor 6 [Source:HGNC Symbol;Acc:HGNC:12036]) HSP 1 Score: 167.933 bits (424), Expect = 1.208e-44 Identity = 127/455 (27.91%), Postives = 205/455 (45.05%), Query Frame = 1
Query: 502 DVIFIDPLEKKYACVVCDQVLRYPVQFDECGHHCCSSCLPELMRVAP-RCPIDQCHIERDKVYVDKEFQKEIDNLGVRCSFYQKGCIWTGVLKELSNHLESCLHRMITCPNNCNVEFEIRFLEKHKQDDCPKRIIQCQFCEASLIAEVEANHLKVCNKFPIPCPNGCKKKEILRENLAEHLESKCVKQEQDCPFSEYGCDFKGKKKRVREHLNDDFVSHLTLMCEA------------------------------------IKENTRIVEEQSKIITQYQTEVGTFEKRIESLEKLYGPQL-IWKIDNYQEKFNEAKTGKKTTIFSAPFMTSRFGYKMALSVCLYGDGKAR-GKHFSLFICICKGDYDSLLLWPFSHRITFTLIDQCQDPEARKN--VVYTVKPNTCKENAPFLGRPTTDRNA-SFGAQKFVELDVLNTLDYIRDDAIFIKAQV 1740
DV F PLE KY C +C LR VQ CGH C +C+ + +R A +CP+D + ++++ D ++EI +L V+C +GC+ L+ L +H C ++ CP C F+ + H DCP+R + C C AS+ E + H + C + C C ++RE + H + C C FS +GC K ++ + HL ++ SH+ ++ +A I+E T +E QS +++ + + T E ++ +E + IWKI N+ + K I S F T + GYK+ + + L R + SLF+ +G+YDS L WPF I T++DQ + P R+N + KP RPT RN FG F+ L+ L +I+DD + ++ +V
Sbjct: 57 DVEFDPPLESKYECPICLMALREAVQ-TPCGHRFCKACIIKSIRDAGHKCPVDNEILLENQLFPDNFAKREILSLMVKCP--NEGCLHKMELRHLEDHQAHCEFALMDCPQ-CQRPFQKFHINIHILKDCPRRQVSCDNCAASMAFEDKEIHDQNCPLANVIC-EYCNTI-LIREQMPNHYDLDCPTAPIPCTFSTFGCHEKMQRNHLARHLQENTQSHMRMLAQAVHSLSVIPDSGYISEVRNFQETIHQLEGRLVRQDHQIRELTAKMETQSMYVSELKRTIRTLEDKVAEIEAQQCNGIYIWKIGNFGMHLKCQEEEKPVVIHSPGFYTGKPGYKLCMRLHLQLPTAQRCANYISLFVHTMQGEYDSHLPWPFQGTIRLTILDQSEAP-VRQNHEEIMDAKPELLA-----FQRPTIPRNPKGFGYVTFMHLEALRQRTFIKDDTLLVRCEV 499
BLAST of TNF receptor-associated factor 4 vs. Ensembl Celegans
Match: trf-1 (TNF Receptor Associated Factor (TRAF) homolog; TRF-1 [Source:UniProtKB/TrEMBL;Acc:G5EG80]) HSP 1 Score: 278.485 bits (711), Expect = 5.925e-87 Identity = 152/413 (36.80%), Postives = 214/413 (51.82%), Query Frame = 1
Query: 505 VIFIDPLEKKYACVVCDQVLRYPVQFDECGHHCCSSCLPELMRVAPRCPIDQCHIERDKVYVDKEFQKEIDNLGVRCSFYQKGCIWTGVLKELSNHLESCLHRMITCPNNCNVEFEIRFLEKHKQDDCPKRIIQCQFCEASLIAEVEANHLKVCNKFPIPCPNGCKKKEILRENLAEHLESKCVKQEQDCPFSEYGCDFKGKKKRVREHLNDDFVSHLTLMCEAIKENTRIVEEQSKIITQYQTEVGTFEKRIESLEKLYGPQLIWKIDNYQEKFNEAKTGKKTTIFSAPFMTSRFGYKMALSVCLYGDGKARGKHFSLFICICKGDYDSLLLWPFSHRITFTLIDQCQDPEARKNVVYTVKPNTCKENAPFLGRPTTDRNASFGAQKFVELDVLNTLDYIRDDAIFIKAQVD 1743
V+F L C +C+Q LR P++ + C HH C C R P C Q I+ + D+ QK+I L V C+F GC W G L L +HL C + C +F LEKH+ C C FC ++ H K C + I CP C + R + H S C + CPF YGC F G K+ +++HL+D+ V HL +C+ I + E + + + E+ +++GPQLIWKID Q++ NEAK+G TTIFS PFM+ RFGYKM CL+GDG + GK SL++ + KG++D L WPF I +L+DQ PE R N+ Y + P K N FL RP +RNA+FG+Q F L +L +Y++DD I+++ VD
Sbjct: 6 VMFKGGLPADCTCPICEQALRDPIKLN-CDHHYCRQCFENENRT-PGCAACQTIIQPELCQHDRAKQKQILALPVVCTFESSGCPWDGQLGTLHDHLSECTFKSSLKCEKCGRQFAKNDLEKHRAK-CELNRAVCSFCNKTIRDSDRERHPKTCPQVIISCPFQCGLTDRPRLEIEAHCPS-CPNVDNVCPFVPYGCTFAGGKESIQQHLSDEPVRHLMYLCDEITDLKGTYELMERDMGSFNDRQTRILSAAETCTEMFGPQLIWKIDKLQQRTNEAKSGADTTIFSVPFMSHRFGYKMMACACLFGDGSSAGKSISLYVLLLKGEFDPTLEWPFHRAIKISLLDQNPRPEDRVNITYVIDPRKLKANEKFLARPRGERNAAFGSQSFCSLAILQ--NYVKDDKIYVQIDVD 412
BLAST of TNF receptor-associated factor 4 vs. Ensembl Celegans
Match: trf-2 (TNF Receptor Associated Factor (TRAF) homolog [Source:UniProtKB/TrEMBL;Acc:Q9N586]) HSP 1 Score: 125.176 bits (313), Expect = 2.182e-31 Identity = 77/228 (33.77%), Postives = 121/228 (53.07%), Query Frame = 1
Query: 1069 DCPFSEYGCDFKGKKKRVREHLNDDFVSHLTLMCEAIKE-NTRIVEEQSKIITQYQTEVGTFEKR--IESLEKLYGPQLIWKIDNYQEKFNEAKTGKK-TTIFSAPFMTSRFGYKMALSVCLYGDGKARGKHFSLFICICKGDYDSLLLWPFSHRITFTLIDQCQDPEARKNVVYTVKPNTCKENAPFLGRPTTDRNASFGAQKFVELDVLNTLDYIRDDAIFIKAQV 1740
DCPF E+GC KG+ V+ H+ DD HL L+C+++ T+I +QS + +Y VG + ES + YG Q ++I +A K +I+S PF + +GYKM YGDG A ++FS+F+C+ KG++D +L WPF +TF+++ + ++ + T+ N E FL RP RN +FG Q F L + ++ D IFI+ +V
Sbjct: 85 DCPFKEHGCHKKGENSEVKRHVRDDRNLHLVLLCQSLNPIRTKINIQQSAYVDKY---VGMLQYMSIAESAFEKYGSQHTFRIPKIGLTVVKATKNKSHRSIYSQPFYSHGYGYKMMAVAAPYGDGLAFREYFSVFVCLMKGEWDDILEWPFRCDVTFSILSD----DKKELLTKTIYVNEMPEIQEFLERPEGLRNGTFGFQNF--LPLAKVTEFAADGDIFIQIKV 303
BLAST of TNF receptor-associated factor 4 vs. Ensembl Fly
Match: Traf4 (gene:FBgn0026319 transcript:FBtr0334401) HSP 1 Score: 185.267 bits (469), Expect = 1.543e-51 Identity = 111/408 (27.21%), Postives = 177/408 (43.38%), Query Frame = 1
Query: 706 KEIDNLGVRCSFYQKGCIWTGVLKELSNHLESCLHRMITCPNNCNV---------------------------EFEIRFLEKH---------------------------KQDDCPKRIIQCQFCEASLIAEVEANHLKVCNKFPIPCPNGCKKKEILRENLAEHLESKCVKQEQDCPFSEYGCDFKGKKKRVREHLNDDFVSHLTLMCEAIKENTRIVEEQSKIITQYQTEVGTFEKRIESLEKLYGPQLIWKIDNYQEKFNEAKTGKKTTIFSAPFMTSRFGYKMALSVCLYGDGKARGKHFSLFICICKGDYDSLLLWPFSHRITFTLIDQCQDPEARKNVVYTVKPNTCKENAPFLGRPTTDRNA-SFGAQKFVELDVLNTLDYIRDDAIFIKAQVDCDEMINI 1764
K I V C +++GC W+ L++L HL +C H CPN C EF LE+H K DC KR+ +C C+ A+ H C + P+ CP C I R L HL +C C F E GC FKG ++ + HL + +HL+LM + ++ ++ + + L Y L+WKI ++ K EA+ + S PF TS++GYK+ S+ L G+G H S++I + G+YD+LL WPFSH ITFTL +Q + V + P+ EN RP+ + + FG +F+ ++L++ +I+ D +F++ +VD +++ +
Sbjct: 88 KHIMGSLVFCIHHKQGCKWSDELRKLKGHLNACKHDATQCPNKCGAQIPRIMMTDHLQYTCTMRRTRCEFCQSEFSGAGLEEHNGSCGQEPVYCEAKCGQRILRGRMTLHKSKDCAKRLRRCAHCQREFSADTLPLHAAQCPRAPLACPQRCDAGPIPRGELEAHLRDECQSLAVSCSFKEAGCRFKGPRQMLEAHLESNAAAHLSLMV--------------ALSSRQGQQIQMLKSAVSKLSINYTGTLLWKITDWSAKMAEARGKDGLELVSPPFYTSQYGYKLQASMFLNGNGPGENTHVSVYIKVLPGEYDALLKWPFSHSITFTLFEQGAQ-SGQGGVAESFVPDPTWEN---FQRPSNEPDQLGFGFPRFISHELLHSRPFIKGDTVFLRVKVDPSKIVAV 477
BLAST of TNF receptor-associated factor 4 vs. Ensembl Fly
Match: Traf4 (gene:FBgn0026319 transcript:FBtr0077429) HSP 1 Score: 185.267 bits (469), Expect = 1.691e-51 Identity = 111/408 (27.21%), Postives = 177/408 (43.38%), Query Frame = 1
Query: 706 KEIDNLGVRCSFYQKGCIWTGVLKELSNHLESCLHRMITCPNNCNV---------------------------EFEIRFLEKH---------------------------KQDDCPKRIIQCQFCEASLIAEVEANHLKVCNKFPIPCPNGCKKKEILRENLAEHLESKCVKQEQDCPFSEYGCDFKGKKKRVREHLNDDFVSHLTLMCEAIKENTRIVEEQSKIITQYQTEVGTFEKRIESLEKLYGPQLIWKIDNYQEKFNEAKTGKKTTIFSAPFMTSRFGYKMALSVCLYGDGKARGKHFSLFICICKGDYDSLLLWPFSHRITFTLIDQCQDPEARKNVVYTVKPNTCKENAPFLGRPTTDRNA-SFGAQKFVELDVLNTLDYIRDDAIFIKAQVDCDEMINI 1764
K I V C +++GC W+ L++L HL +C H CPN C EF LE+H K DC KR+ +C C+ A+ H C + P+ CP C I R L HL +C C F E GC FKG ++ + HL + +HL+LM + ++ ++ + + L Y L+WKI ++ K EA+ + S PF TS++GYK+ S+ L G+G H S++I + G+YD+LL WPFSH ITFTL +Q + V + P+ EN RP+ + + FG +F+ ++L++ +I+ D +F++ +VD +++ +
Sbjct: 97 KHIMGSLVFCIHHKQGCKWSDELRKLKGHLNACKHDATQCPNKCGAQIPRIMMTDHLQYTCTMRRTRCEFCQSEFSGAGLEEHNGSCGQEPVYCEAKCGQRILRGRMTLHKSKDCAKRLRRCAHCQREFSADTLPLHAAQCPRAPLACPQRCDAGPIPRGELEAHLRDECQSLAVSCSFKEAGCRFKGPRQMLEAHLESNAAAHLSLMV--------------ALSSRQGQQIQMLKSAVSKLSINYTGTLLWKITDWSAKMAEARGKDGLELVSPPFYTSQYGYKLQASMFLNGNGPGENTHVSVYIKVLPGEYDALLKWPFSHSITFTLFEQGAQ-SGQGGVAESFVPDPTWEN---FQRPSNEPDQLGFGFPRFISHELLHSRPFIKGDTVFLRVKVDPSKIVAV 486
BLAST of TNF receptor-associated factor 4 vs. Ensembl Fly
Match: Traf-like (gene:FBgn0030748 transcript:FBtr0074273) HSP 1 Score: 75.8702 bits (185), Expect = 3.113e-14 Identity = 51/184 (27.72%), Postives = 95/184 (51.63%), Query Frame = 1
Query: 1192 RIVEEQSKIITQYQTEVGTFEKRIESLEKLYGPQLIWKIDNYQEKFNEAKTGKKTTIFSAPFMTSRFGYKMALSVCLYGDGKARGKHFSLFICICKGDYDSLLLWPFSHRITFTLIDQCQDPEARKNVVYTVKPNTCKENAPFLGRPTTDRNASFGAQKF-VELDVLNTLDYIRDDAIFIKAQV 1740
R + + + I+ +T++ ++RI S++ + G LIW+I +Y +K E+K T + SA F FGY + L + L G G +G++ + + G+YD LL WP + + DQC + ++ V T+ F+ + + D S Q F + V+ + +Y+R+D++FI+ +V
Sbjct: 282 RALHQTMQNISDLETQMA-MQQRIASVQNIRG-HLIWRIKDYSKKLEESKQ-YDTILHSAMFSNKAFGYALRLDIYLNGKGTWKGRNMIACLNVLSGEYDPLLAWPCRLQAEIIIRDQCTNVADAEDYVKTI----------FVRKKSDDFIQS--NQYFHIPHKVITSRNYLRNDSMFIEVRV 450
BLAST of TNF receptor-associated factor 4 vs. Ensembl Fly
Match: Traf-like (gene:FBgn0030748 transcript:FBtr0074275) HSP 1 Score: 75.8702 bits (185), Expect = 3.212e-14 Identity = 51/184 (27.72%), Postives = 95/184 (51.63%), Query Frame = 1
Query: 1192 RIVEEQSKIITQYQTEVGTFEKRIESLEKLYGPQLIWKIDNYQEKFNEAKTGKKTTIFSAPFMTSRFGYKMALSVCLYGDGKARGKHFSLFICICKGDYDSLLLWPFSHRITFTLIDQCQDPEARKNVVYTVKPNTCKENAPFLGRPTTDRNASFGAQKF-VELDVLNTLDYIRDDAIFIKAQV 1740
R + + + I+ +T++ ++RI S++ + G LIW+I +Y +K E+K T + SA F FGY + L + L G G +G++ + + G+YD LL WP + + DQC + ++ V T+ F+ + + D S Q F + V+ + +Y+R+D++FI+ +V
Sbjct: 304 RALHQTMQNISDLETQMA-MQQRIASVQNIRG-HLIWRIKDYSKKLEESKQYD-TILHSAMFSNKAFGYALRLDIYLNGKGTWKGRNMIACLNVLSGEYDPLLAWPCRLQAEIIIRDQCTNVADAEDYVKTI----------FVRKKSDDFIQS--NQYFHIPHKVITSRNYLRNDSMFIEVRV 472
BLAST of TNF receptor-associated factor 4 vs. Ensembl Fly
Match: Traf-like (gene:FBgn0030748 transcript:FBtr0308606) HSP 1 Score: 75.0998 bits (183), Expect = 3.735e-14 Identity = 50/186 (26.88%), Postives = 94/186 (50.54%), Query Frame = 1
Query: 1192 RIVEEQSKIITQYQTEVGTFEKRIESLEKLYGPQLIWKIDNYQEKFNEAKTGKKTTIFSAPFMTSRFGYKMALSVCLYGDGKARGKHFSLFICICKGDYDSLLLWPFSHRITFTLIDQCQDPEARKNVVYTVKPNTCKENAPFLGRPTTD---RNASFGAQKFVELDVLNTLDYIRDDAIFIKAQV 1740
R + + + I+ +T++ ++RI S++ + G LIW+I +Y +K E+K T + SA F FGY + L + L G G +G++ + + G+YD LL WP + + DQC + ++ V T+ F+ + + D N F + V+ + +Y+R+D++FI+ +V
Sbjct: 225 RALHQTMQNISDLETQMA-MQQRIASVQNIRG-HLIWRIKDYSKKLEESKQYD-TILHSAMFSNKAFGYALRLDIYLNGKGTWKGRNMIACLNVLSGEYDPLLAWPCRLQAEIIIRDQCTNVADAEDYVKTI----------FVRKKSDDFIQSNQYF----HIPHKVITSRNYLRNDSMFIEVRV 393
BLAST of TNF receptor-associated factor 4 vs. Ensembl Zebrafish
Match: traf4a (tnf receptor-associated factor 4a [Source:ZFIN;Acc:ZDB-GENE-040308-1]) HSP 1 Score: 250.751 bits (639), Expect = 4.133e-76 Identity = 143/482 (29.67%), Postives = 226/482 (46.89%), Query Frame = 1
Query: 502 DVIFIDPLEKKYACVVCDQVLRYPVQFDECGHHCCSSCLPELMRVAP-RCPIDQCHIERDKVYVDKEFQKEIDNLGVRCSFYQKGCIWTGVL---------------------------KELSNHLES---------------------------CLHRMITCPNNCNVEFEIRFLEKHKQDDCPKRIIQCQFCEASLIAEVEANHLKVCNKFPIPCPNGCKKKEILRENLAEHLESKCVKQEQDCPFSEYGCDFKGKKKRVREHLNDDFVSHLTLMCEAIKENTRIVEEQSKIITQYQTEVGTFEKRIESLEKLYGPQLIWKIDNYQEKFNEAKTGKKTTIFSAPFMTSRFGYKMALSVCLYGDGKARGKHFSLFICICKGDYDSLLLWPFSHRITFTLIDQCQDPEARK--NVVYTVKPNTCKENAPFLGRPTTDRNA------SFGAQKFVELDVLNTLDYIRDDAIFIKAQVDCDEMI 1758
D F++ ++++ C +C + +R PVQ CGH C +CL E + +CP DQ ++ K+Y D E +++I L +RC ++GC WTG + ++L HL+ C + C N C R L +H +CPKR C++C + + NH C +FP+ CPN C I RE+LA H++ C CPF E GC + K + HL + SHLT+MC ++ + + E+ + +E L + LIWK+ +Y K EAK FS PF T R+GYK+ +S L G+G G H S++I + G+YD+LL WPFS+++TF+++DQ DP K ++ T P+ +N +P + RN+ FG KF+ + + +YIRD++IF+KA ++ + I
Sbjct: 5 DYKFLEKPKRRFQCPLCSKAMREPVQVSTCGHRFCDTCLQEFLSEGVFKCPEDQLPLDYAKIYPDPELEQQILALPIRCIHSEEGCRWTGQMKQLQSHFSTCAFNVIPCPNRCSVKLTRRDLPEHLQHDCPKRKVKCEFCGSEFTGEAYENHQGICPQESVYCENKCGARMMRRLLSQHTMTECPKRTQPCKYCGKEFVYDTIQNHQYHCPRFPVQCPNQCGTPNIAREDLANHVKESCGSALVLCPFKEAGCKHRCPKMAIGRHLEESTKSHLTMMC--------------SLVGRQRQEILELRREMEELSVSHDGVLIWKLTDYSRKLQEAKLRNNHEFFSPPFYTHRYGYKLQVSAFLNGNGSGEGSHLSIYIRVLPGEYDNLLEWPFSYKVTFSILDQ-SDPSLSKPQHITETFNPDPNWKN---FQKPCSSRNSLDESTLGFGYPKFISHEEIKKRNYIRDNSIFLKASIEIPQKI 468
BLAST of TNF receptor-associated factor 4 vs. Ensembl Zebrafish
Match: traf4a (tnf receptor-associated factor 4a [Source:ZFIN;Acc:ZDB-GENE-040308-1]) HSP 1 Score: 250.751 bits (639), Expect = 4.133e-76 Identity = 143/482 (29.67%), Postives = 226/482 (46.89%), Query Frame = 1
Query: 502 DVIFIDPLEKKYACVVCDQVLRYPVQFDECGHHCCSSCLPELMRVAP-RCPIDQCHIERDKVYVDKEFQKEIDNLGVRCSFYQKGCIWTGVL---------------------------KELSNHLES---------------------------CLHRMITCPNNCNVEFEIRFLEKHKQDDCPKRIIQCQFCEASLIAEVEANHLKVCNKFPIPCPNGCKKKEILRENLAEHLESKCVKQEQDCPFSEYGCDFKGKKKRVREHLNDDFVSHLTLMCEAIKENTRIVEEQSKIITQYQTEVGTFEKRIESLEKLYGPQLIWKIDNYQEKFNEAKTGKKTTIFSAPFMTSRFGYKMALSVCLYGDGKARGKHFSLFICICKGDYDSLLLWPFSHRITFTLIDQCQDPEARK--NVVYTVKPNTCKENAPFLGRPTTDRNA------SFGAQKFVELDVLNTLDYIRDDAIFIKAQVDCDEMI 1758
D F++ ++++ C +C + +R PVQ CGH C +CL E + +CP DQ ++ K+Y D E +++I L +RC ++GC WTG + ++L HL+ C + C N C R L +H +CPKR C++C + + NH C +FP+ CPN C I RE+LA H++ C CPF E GC + K + HL + SHLT+MC ++ + + E+ + +E L + LIWK+ +Y K EAK FS PF T R+GYK+ +S L G+G G H S++I + G+YD+LL WPFS+++TF+++DQ DP K ++ T P+ +N +P + RN+ FG KF+ + + +YIRD++IF+KA ++ + I
Sbjct: 5 DYKFLEKPKRRFQCPLCSKAMREPVQVSTCGHRFCDTCLQEFLSEGVFKCPEDQLPLDYAKIYPDPELEQQILALPIRCIHSEEGCRWTGQMKQLQSHFSTCAFNVIPCPNRCSVKLTRRDLPEHLQHDCPKRKVKCEFCGSEFTGEAYENHQGICPQESVYCENKCGARMMRRLLSQHTMTECPKRTQPCKYCGKEFVYDTIQNHQYHCPRFPVQCPNQCGTPNIAREDLANHVKESCGSALVLCPFKEAGCKHRCPKMAIGRHLEESTKSHLTMMC--------------SLVGRQRQEILELRREMEELSVSHDGVLIWKLTDYSRKLQEAKLRNNHEFFSPPFYTHRYGYKLQVSAFLNGNGSGEGSHLSIYIRVLPGEYDNLLEWPFSYKVTFSILDQ-SDPSLSKPQHITETFNPDPNWKN---FQKPCSSRNSLDESTLGFGYPKFISHEEIKKRNYIRDNSIFLKASIEIPQKI 468
BLAST of TNF receptor-associated factor 4 vs. Ensembl Zebrafish
Match: traf4b (tnf receptor-associated factor 4b [Source:ZFIN;Acc:ZDB-GENE-040305-2]) HSP 1 Score: 217.624 bits (553), Expect = 1.771e-63 Identity = 135/488 (27.66%), Postives = 224/488 (45.90%), Query Frame = 1
Query: 499 VDVIFIDPLEKKYACVVCDQVLRYPVQFDECGHHCCSSCLPELMRVAP-RCPIDQCHIERDKVYVDKEFQKEIDNLGVRCSFYQKGCIWTG---------------------------VLKELSNHLES---------------------------CLHRMITCPNNCNVEFEIRFLEKHKQDDCPKRIIQCQFCEASLIAEVEANHLKVCNKFPIPCPNGCKKKEILRENLAEHLESKCVKQEQDCPFSEYGCDFKGKKKRVREHLNDDFVSHLTLMCEAIKENTRIVEEQSKIITQYQTEVGTFEKRIESLEKLYGPQLIWKIDNYQEKFNEAKTGKKT--TIFSAPFMTSRFGYKMALSVCLYGDGKARGKHFSLFICICKGDYDSLLLWPFSHRITFTLIDQCQDPEARK--NVVYTVKPNTCKEN--APFLGRPTTDRNA-------SFGAQKFVELDVLNTLDYIRDDAIFIKAQVDCDEMI 1758
+D+ F++ +K+ C +C++ +R PVQ CGH C +CL E + CP DQ ++ K++ D E +++I +L +RC ++GC WT + +EL HL+ C + C N C R L +H +C KR + C++C+ + + NH + C +FP+ CPN C I R+ L H++ C CPF E GC + K V HL + +HL+L+C ++ + + E+ +R+E L L+WK+ ++ ++ EAKT +FS F + +GY++ +S L G+G H S+++ + G+YD LL WPF +R++F+L+DQC DP K ++ T P+ +N P G + R FG KF+ + + +YIRD+A+FIKA +D + I
Sbjct: 4 LDLKFLERPRRKFYCPLCEKPMREPVQVSTCGHRFCDTCLQEYLSEGVFTCPEDQLPLDYAKIFPDLELEQQILSLPIRCIHSEEGCRWTAQNKLLQAHLSVCEFNVVSCPNRCSVKLLRRELPEHLQHDCAKRKLHCDHCGEQFTGEAYENHQGVCPEESVYCENKCGARMVRRLLAQHSVSECLKRKLPCRYCKKEFLYDTIQNHQQQCPRFPMQCPNRCGTPGITRDTLMAHVKEGCSTAMVLCPFKEAGCKHRSPKTGVARHLEEAAPTHLSLLC--------------GLVNRQRLELRDLRRRMEELSGSRDGTLLWKLTDFSQRLQEAKTRTSGCLELFSPAFYSHNYGYRLQVSAFLNGNGSGEDTHMSVYLRVLPGEYDGLLEWPFPYRVSFSLLDQC-DPALTKPQHITETFSPDPTWKNFQRPRPGALGSIRGGCLDESMLGFGYPKFISHEEMKKRNYIRDNAVFIKASIDVVQKI 476
BLAST of TNF receptor-associated factor 4 vs. Ensembl Zebrafish
Match: traf6 (TNF receptor-associated factor 6 [Source:NCBI gene;Acc:554561]) HSP 1 Score: 172.17 bits (435), Expect = 3.612e-46 Identity = 132/501 (26.35%), Postives = 219/501 (43.71%), Query Frame = 1
Query: 442 FHNQIKNPPIITNSN----NQNDVDVIFIDPLEKKYACVVCDQVLRYPVQFDECGHHCCSSCLPELMR-VAPRCPIDQCHIERDKVYVDKEFQKEIDNLGVRCSFYQKGCIWTGVLKELSNHLESCLHRMITCPNNCNVEFEIRFLEKHKQDDCPKRIIQCQFCEASLIAEVEANHLKVCNKFPIPCPNGCKKKEILRENLAEHLESKCVKQEQDCPFSEYGCDFKGKKKRVREHLNDDFVSHLTLMCEAIKENT---------------------------------------RIVEEQSKIITQYQ-------------TEVGTFEKRIESLE--------KLYGPQLIWKIDNYQEKFNEAKTGKKTTIFSAPFMTSRFGYKMALSVCLYGDGKARGKHF-SLFICICKGDYDSLLLWPFSHRITFTLIDQCQDPEARKNV-VYTVKPNTCKENAPFLGRPTTDRNA-SFGAQKFVELDVLNTLDYIRDDAIFIKAQV 1740
F + +NP I+ S+ +Q DV F PLE KY C +C LR VQ CGH C SC+ + +R +CP+D + ++++ D ++EI +L V+CS + GC L++L HL C CP C I L++HK C +RI+ C C S + V+ NH + C C C + E++R+ LA H ++ C+K C FS +GC K + + +H+ + H+ M E ++ T ++E + +++ Q Q +V +++ SLE + Y +W+++N+ + G+ + S PF T R GYK+ L + L R +F SLF+ +G++DS L WP I ++DQ E + ++ V KP+ RPT RN FG F+ L L ++++D + ++ +V
Sbjct: 34 FLSPTENPSTISVSSSMPPDQQGYDVEFDPPLESKYECPICLMGLRSAVQ-TPCGHRFCDSCIRKSIRDTGQKCPVDNEVLLEEQLFPDNFAKREILSLTVKCSNF--GCSEKMELRQLEKHLSQCRFATAPCP-QCQESVPISHLDEHKSQHCLQRIMTCPDCAGSFVYAVKQNHEQFCPFANTVC-EYC-EMELIRDQLALHCDTDCLKAPVACTFSTFGCREKMTRNELAQHMQEFTQMHMRYMAEFLRSQTLNNCTMPSAAAHLSSDDRGASARSPDSCQCKQELLNLRETVLELEGRLVRQDQQIRELCIHNDTQKNQVTELRRKLVSLEESTRELEAQQYQGIYVWRVENFSHHLRNQEAGQPIVLHSPPFYTGRPGYKLCLRLHLQTPSAPRCSNFISLFVHTMQGEFDSQLSWPLQGTIRLAVLDQV---EGQHHIEVMETKPDL-----QAFQRPTVMRNPKGFGYVTFLHLQALRQRGFVKEDVLLVRCEV 520
BLAST of TNF receptor-associated factor 4 vs. Ensembl Zebrafish
Match: traf6 (TNF receptor-associated factor 6 [Source:NCBI gene;Acc:554561]) HSP 1 Score: 172.17 bits (435), Expect = 3.612e-46 Identity = 132/501 (26.35%), Postives = 219/501 (43.71%), Query Frame = 1
Query: 442 FHNQIKNPPIITNSN----NQNDVDVIFIDPLEKKYACVVCDQVLRYPVQFDECGHHCCSSCLPELMR-VAPRCPIDQCHIERDKVYVDKEFQKEIDNLGVRCSFYQKGCIWTGVLKELSNHLESCLHRMITCPNNCNVEFEIRFLEKHKQDDCPKRIIQCQFCEASLIAEVEANHLKVCNKFPIPCPNGCKKKEILRENLAEHLESKCVKQEQDCPFSEYGCDFKGKKKRVREHLNDDFVSHLTLMCEAIKENT---------------------------------------RIVEEQSKIITQYQ-------------TEVGTFEKRIESLE--------KLYGPQLIWKIDNYQEKFNEAKTGKKTTIFSAPFMTSRFGYKMALSVCLYGDGKARGKHF-SLFICICKGDYDSLLLWPFSHRITFTLIDQCQDPEARKNV-VYTVKPNTCKENAPFLGRPTTDRNA-SFGAQKFVELDVLNTLDYIRDDAIFIKAQV 1740
F + +NP I+ S+ +Q DV F PLE KY C +C LR VQ CGH C SC+ + +R +CP+D + ++++ D ++EI +L V+CS + GC L++L HL C CP C I L++HK C +RI+ C C S + V+ NH + C C C + E++R+ LA H ++ C+K C FS +GC K + + +H+ + H+ M E ++ T ++E + +++ Q Q +V +++ SLE + Y +W+++N+ + G+ + S PF T R GYK+ L + L R +F SLF+ +G++DS L WP I ++DQ E + ++ V KP+ RPT RN FG F+ L L ++++D + ++ +V
Sbjct: 34 FLSPTENPSTISVSSSMPPDQQGYDVEFDPPLESKYECPICLMGLRSAVQ-TPCGHRFCDSCIRKSIRDTGQKCPVDNEVLLEEQLFPDNFAKREILSLTVKCSNF--GCSEKMELRQLEKHLSQCRFATAPCP-QCQESVPISHLDEHKSQHCLQRIMTCPDCAGSFVYAVKQNHEQFCPFANTVC-EYC-EMELIRDQLALHCDTDCLKAPVACTFSTFGCREKMTRNELAQHMQEFTQMHMRYMAEFLRSQTLNNCTMPSAAAHLSSDDRGASARSPDSCQCKQELLNLRETVLELEGRLVRQDQQIRELCIHNDTQKNQVTELRRKLVSLEESTRELEAQQYQGIYVWRVENFSHHLRNQEAGQPIVLHSPPFYTGRPGYKLCLRLHLQTPSAPRCSNFISLFVHTMQGEFDSQLSWPLQGTIRLAVLDQV---EGQHHIEVMETKPDL-----QAFQRPTVMRNPKGFGYVTFLHLQALRQRGFVKEDVLLVRCEV 520
BLAST of TNF receptor-associated factor 4 vs. Ensembl Xenopus
Match: sytl2 (synaptotagmin like 2 [Source:Xenbase;Acc:XB-GENE-945155]) HSP 1 Score: 269.24 bits (687), Expect = 6.755e-83 Identity = 152/482 (31.54%), Postives = 238/482 (49.38%), Query Frame = 1
Query: 502 DVIFIDPLEKKYACVVCDQVLRYPVQFDECGHHCCSSCLPELMRVAP-RCPIDQCHIERDKVYVDKEFQKEIDNLGVRCSFYQKGCIWTGVLKELSNHLESCLHRMITCPNNCNVEFEIRFLEKHKQDDCPKRIIQCQFCE---------------------------ASLIAEVEANHLKV---------------------------CNKFPIPCPNGCKKKEILRENLAEHLESKCVKQEQDCPFSEYGCDFKGKKKRVREHLNDDFVSHLTLMCEAIKENTRIVEEQSKIITQYQTEVGTFEKRIESLEKLYGPQLIWKIDNYQEKFNEAKTGKKTTIFSAPFMTSRFGYKMALSVCLYGDGKARGKHFSLFICICKGDYDSLLLWPFSHRITFTLIDQCQDPEARK--NVVYTVKPNTCKENAPFLGRPTTDRNA------SFGAQKFVELDVLNTLDYIRDDAIFIKAQVDCDEMI 1758
D F++ L +K+ C +C + +R PVQ CGH C +CL E + +CP DQ ++ K+Y D++ + ++ L +RC ++GC W+G LK+L HL C +I CPN C+ + R L +H Q DCPKR ++C+FC A ++ V + H V C ++P PCPN C I RE+L+ HL+ C CPF + GC +G K + HL ++ +HL++M S ++++ + E+ K++E L LIWKI +Y K EAK FS PF T ++GYK+ +S L G+G G + S++I + G+YD+LL WPFS+R+TF+L+DQ DP K ++ T P+ +N +PT RN+ FG KF+ + + +Y+RD+AIF++A V+ + I
Sbjct: 5 DYKFLEKLRRKFLCPLCGKAMREPVQVSTCGHRFCDTCLQEFLSEGVFKCPEDQLPLDYAKIYPDRDLETQVMGLSIRCIHSEEGCRWSGQLKQLQPHLNICAFNVIPCPNRCSTKLIRRDLPEHMQHDCPKRKVRCEFCGADFTGEAYEDHQGCCPQESVYCENKCGARMMRRVLSQHSLVECPKRTQPCPYCNKEFVFDTIQSHQYQCPRYPTPCPNQCGIASIAREDLSNHLKDSCSSALVLCPFKDSGCKHRGPKITISRHLEENMRAHLSMM--------------SSLVSRQRQEILELRKQVEELSVSSEGVLIWKISDYSRKVQEAKVRGNFESFSPPFYTHKYGYKLQVSAFLNGNGSGEGSYLSVYIRVLPGEYDNLLEWPFSYRVTFSLLDQ-SDPSLSKPQHITETFNPDPNWKN---FQKPTGSRNSLDESTLGFGYPKFISHEDIRKRNYVRDNAIFLRASVEIPQKI 468
BLAST of TNF receptor-associated factor 4 vs. Ensembl Xenopus
Match: TRAF2 (TNF receptor associated factor 2 [Source:NCBI gene;Acc:100494415]) HSP 1 Score: 159.458 bits (402), Expect = 3.103e-42 Identity = 124/467 (26.55%), Postives = 198/467 (42.40%), Query Frame = 1
Query: 508 IFIDPLEKKYACVVCDQVLRYPVQFDECGHHCCSSCLPELMRVAPRCPIDQCHIERDKVYVDKEFQKEIDNLG--VRCSFYQKGCIWTGVLKELSNHLESCLHRMITCPNNCNVEFEIRFLEKHKQDDCPKRIIQCQFCEASLIAEVEANHLKVCNKFPIPCPNGCKKKEILRENLAEHLESKCVKQEQDCPFSEYGCDFKGKKKRVREHLNDDFVSHL----------------------------------------TLMCEAIKENTRIVEEQSK-----------IITQYQTEVGTFEKRIESLE-KLYGPQLIWKIDNYQEKFNEAKTGKKTTIFSAPFMTSRFGYKMALSVCLYGDGKARGKHFSLFICICKGDYDSLLLWPFSHRITFTLIDQCQDPEARKNVVYTVKPNTCKENAPFLGRPTTDRNASFGAQKFVELDVLNTLD-YIRDDAIFIKAQVD 1743
I LE KY C C +LR P+Q +CGH CS CL +++R R N G C + WTG L + H C + + CP C + H + +CP+R + C++C+ S H ++C KFP+ C GC +K+I RE + + C+ C ++ GC + + EH N HL +++ ++ ++ EE ++ + Q + V E R++ E Y IWKI + +K +A G+ +FS PF T+++GYKM L + L GDG R H SLF + KG+ D+LL WPF+ ++T L+DQ R++V+ +P+ ++ RP ++ N + G F ++ L + Y+RDD IF+K VD
Sbjct: 26 ILGTKLEVKYLCSDCKNLLRRPLQ-AQCGHRYCSHCLNKIIRWVAR------------------------NWGGVPECPAVCERSDWTGALISVG-HEGKCPYLLAPCPA-CKTIIRAANRDLHSERECPERKLNCRYCKLSFYFPDIKAHDEICPKFPMTC-EGCGRKKIPREKVRLFV---CMP----CRYAAVGCTEMVENDKCLEHENKSLAEHLAKGSPAPPANAPPNNSAKVAEMLLKFDTLDKKNTTFENIVSVLNREVERSSHAAEELARQLRAADTRLERTLGQKELIVAELETRMQESELSTYDGVFIWKISEFGKKRQDAINGRCPAMFSPPFYTNKYGYKMCLRIYLNGDGTGRNTHLSLFFVVMKGNNDALLRWPFNQKVTLMLLDQ----NNREHVIDAFRPDV---SSSSFQRPISEMNIASGCPLFCQVSKLEGKNSYVRDDTIFVKVIVD 450
BLAST of TNF receptor-associated factor 4 vs. Ensembl Xenopus
Match: TRAF2 (TNF receptor associated factor 2 [Source:NCBI gene;Acc:100494415]) HSP 1 Score: 159.458 bits (402), Expect = 5.154e-42 Identity = 123/487 (25.26%), Postives = 199/487 (40.86%), Query Frame = 1
Query: 508 IFIDPLEKKYACVVCDQVLRYPVQFDECGHHCCSSCLPELMRVAPRCPIDQCHIERDKVYVDKEFQKEIDNLG--VRCSFYQKGCIWTGVLKELSNHLESCLHRMITCPNNCNVEFEIRFLEKHKQDDCPKRIIQCQFCEASLIAEVEANHLKVCNKFPIPCPNGCKKKEILRENLAEHL--ESKCVKQEQDCPFSEYGCDFKGKKKRVREHLNDDFVSHL------------------------------------------------TLMCEAIKENTRIVEEQSKIITQYQTEVGTFEKRIESLEKLYGPQ----------------------LIWKIDNYQEKFNEAKTGKKTTIFSAPFMTSRFGYKMALSVCLYGDGKARGKHFSLFICICKGDYDSLLLWPFSHRITFTLIDQCQDPEARKNVVYTVKPNTCKENAPFLGRPTTDRNASFGAQKFVELDVLNTLD-YIRDDAIFIKAQVD 1743
I LE KY C C +LR P+Q +CGH CS CL +++R R N G C + WTG L + H C + + CP C + H + +CP+R + C++C+ S H ++C KFP+ C GC +K+I RE + + S+ + C ++ GC + + EH N HL +++ ++ ++ EE ++ + Q +V ++ LE+ G + IWKI + +K +A G+ +FS PF T+++GYKM L + L GDG R H SLF + KG+ D+LL WPF+ ++T L+DQ R++V+ +P+ + RP ++ N + G F ++ L + Y+RDD IF+K VD
Sbjct: 26 ILGTKLEVKYLCSDCKNLLRRPLQ-AQCGHRYCSHCLNKIIRWVAR------------------------NWGGVPECPAVCERSDWTGALISVG-HEGKCPYLLAPCP-ACKTIIRAANRDLHSERECPERKLNCRYCKLSFYFPDIKAHDEICPKFPMTC-EGCGRKKIPREKVRLFVCSFSRNITLSLPCRYAAVGCTEMVENDKCLEHENKSLAEHLAKVWDYIQHGRKEQNDLSVRMGSLSVQGSPAPPFDTLDKKNTTFENIVSVLNREVERSSHAAEELARQLRAAQEKVEALTTKVRQLERTLGQKELIVAELETRMQESELSTYDGVFIWKISEFGKKRQDAINGRCPAMFSPPFYTNKYGYKMCLRIYLNGDGTGRNTHLSLFFVVMKGNNDALLRWPFNQKVTLMLLDQ----NNREHVIDAFRPDVSSSS---FQRPISEMNIASGCPLFCQVSKLEGKNSYVRDDTIFVKVIVD 477
BLAST of TNF receptor-associated factor 4 vs. Ensembl Xenopus
Match: ssh2 (slingshot protein phosphatase 2 [Source:Xenbase;Acc:XB-GENE-993093]) HSP 1 Score: 147.132 bits (370), Expect = 2.532e-37 Identity = 135/507 (26.63%), Postives = 227/507 (44.77%), Query Frame = 1
Query: 511 FIDPLEKKYACVVCDQVLRYPVQFDECGHHCCSSCLPELMR-VAPRCPIDQCHIERDKVYVDKEFQKEIDNLGVRCSFYQKG-----------------------------CIWTGVLKELSNHLE-SCLHR---------------------------MITCPNNCNVEFEIRF------LEKHKQDDCPKRIIQCQFCEASLIAEV--------EAN------HLKVCNKFPIPCPNGCKKKEILRENLAEHLESKCVKQEQDCPFSEYGCDFKGKKKRVREH--LNDDF------VSHLTLMCE-AIKENTRIVEEQ----SKIITQYQTEVGTFEKRIESLEKL-YGPQLIWKIDNYQEKFNEAKTGKKTTIFSAPFMTSRFGYKMALSVCLYGDGKARGKHFSLFICICKGDYDSLLLWPFSHRITFTLIDQCQDPEARKNVVYTVKPNTCKENAPFLGRPTTDRNASFGAQKFVELDVLNTLDYIRDDAIFIKAQVDCDEM 1755
F+ P+E+KY C C VL P Q ECGH C +C+ ++ +P+C + +I +DKV+ D ++E+ L + C +G C + K+LS+H+E +C +R +I+CP+ C+V+ +R ++ H+ + + + L A+V E N H ++C+ F I + KE LR N A ++ + V + Q + + + ++ E + ++ +S L +M + A N ++E Q ++++ + + + R + LE Y LIWKI +Y+ + EA GK +++S PF T FGYKM V L GDG +G H SLF I +G+YD+LL WPF +++ L+DQ +R+++ KP+ N+ +PT + N + G FV VL YI+DD IFIK VD ++
Sbjct: 38 FLKPVEEKYKCEKCRLVLCNPRQ-TECGHRFCETCMNAILSSTSPQCMACEDNITKDKVFKDNCCRREVLALQMFCRNETRGCKELITLGNLLIHLKSDCQFEELSCPRADCKEKVIRKDLSDHIEKTCKYRETPCKFCRNQVPLVEMQKHEDVDCPSVVISCPHMCSVKSLLRSEGTNQQIKAHEASSAVQHVNLMKEWSNYLEAKVSMLQNESSEKNKSIQILHNQMCS-FEIEIE---RHKEQLRNNEARIIQLQRVIEGQADKLKDLDKEIRNLRQTGDEADGMKSNYESLQNRLSQLEVMAKNAASWNPGVLETQINRHDQMLSVHDIRLADMDLRFQVLETASYNGVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVSLMLMDQ---GPSRRHLGDAFKPDP---NSSSFKKPTGEMNIASGCPVFVAQTVLENGTYIKDDTIFIKVIVDTSDL 533
BLAST of TNF receptor-associated factor 4 vs. Ensembl Xenopus
Match: slc12a1 (solute carrier family 12 member 1 [Source:Xenbase;Acc:XB-GENE-479925]) HSP 1 Score: 144.821 bits (364), Expect = 1.817e-36 Identity = 136/516 (26.36%), Postives = 219/516 (42.44%), Query Frame = 1
Query: 502 DVIFIDPLEKKYACVVCDQVLRYPVQFDECGHHCCSSCLPELMRVA--PRCPIDQCHIERDKVYVDKEFQKEIDNLGVRC------------SFYQK---------------GCIWTGVLKELSNHLES---------------------CLHRMITCPNNCNVEFEIRFLEKHKQDDCPKRIIQCQFCEAS-----LIAEVEANHLKVCNKFPIPCPNGCKKKEILRENLAEHLESKCVKQEQDC-PFSEY----GCDFKGKKKRV------------------REHLNDDFVSHLTLM---------CEAIKENTRIVEEQSK----IITQYQTEVGTFEKRIESLEKL-YGPQLIWKIDNYQEKFNEAKTGKKTTIFSAPFMTSRFGYKMALSVCLYGDGKARGKHFSLFICICKGDYDSLLLWPFSHRITFTLIDQCQDPEARKNV---VYTVKPNTCKENAPFLGRPTTDRNASFGAQKF---VELDVLNTLDYIRDDAIFIKAQVDCDEM 1755
+ +F++ L+ +Y C C VL P Q CGH C C+ L+ ++ P+CPID +I+ +++ D ++E+ NL V C YQ+ GC + KEL HLES CL M +C NN F L+KH + CP+ +QC F L + + L +C + G ++ L+E+ + L E++C F ++ G K +EH D L + EA K+ ++ Q K +++ ++ ++ + E+R +E Y +LIWKI +Y+ K EA G+ +IFS F TS GY++ L GDG +G SL+ + KG++DS+LLWPF ++T L+DQ +KN V+ PN+ RP ++ N + G +F +L+ YI+DD +FIK VD ++
Sbjct: 31 EYLFVEQLQDRYKCASCHLVLHNPHQTG-CGHRFCEKCISNLIELSETPQCPIDMENIKSHEIFKDNCCKREVLNLLVYCKNSPACDVKVMLGRYQEHLGQCLYEMTLCSNDGCHDQMIRKELKGHLESECKLRQEACIYCKQTMSLCLACLDYMFSCRNNYKKIFFSFQLDKHLCE-CPEAELQCTFSNYGCNVMVLYHSLSVHFLYLCTFTSVSQVLGLQQNLDLKEHQIQQLSDTVKWCEKECHQFGQFTGSNGNSLSSTKTLASYIDKSMWLEEQVIQLVSKEHSRLDLRPILDTLESTKQRLSTLEAYKDRIDNLDGQFKKHDVLLSNHKMQMTSNEERFRLVEGTSYNGKLIWKITDYERKKREAMEGRAVSIFSQHFYTSWCGYRLCARAYLNGDGSGKGSFLSLYFVVMKGEFDSILLWPFKQKVTLMLLDQ----SGKKNHITDVFRADPNSSS-----FKRPDSEMNIASGCPRFASHAQLENPKNGCYIKDDTLFIKIVVDLTDL 535
BLAST of TNF receptor-associated factor 4 vs. Ensembl Mouse
Match: Traf4 (TNF receptor associated factor 4 [Source:MGI Symbol;Acc:MGI:1202880]) HSP 1 Score: 245.358 bits (625), Expect = 6.398e-74 Identity = 143/479 (29.85%), Postives = 222/479 (46.35%), Query Frame = 1
Query: 502 DVIFIDPLEKKYACVVCDQVLRYPVQFDECGHHCCSSCLPELMRVAP-RCPIDQCHIERDKVYVDKEFQKEIDNLGVRCSFYQKGCIWTGVLKELSNHLESCLHRMITCPNNCNVEFEIRFLEKHKQDDCPKRIIQCQF---------------------------CEASLIAEVEANHLKV---------------------------CNKFPIPCPNGCKKKEILRENLAEHLESKCVKQEQDCPFSEYGCDFKGKKKRVREHLNDDFVSHLTLMCEAIKENTRIVEEQSKIITQYQTEVGTFEKRIESLEKLYGPQLIWKIDNYQEKFNEAKTGKKTTIFSAPFMTSRFGYKMALSVCLYGDGKARGKHFSLFICICKGDYDSLLLWPFSHRITFTLIDQCQDPEARK--NVVYTVKPNTCKEN--APFLGRPTTDRNA-SFGAQKFVELDVLNTLDYIRDDAIFIKAQVDCDEMI 1758
D F++ +++ C +C + +R PVQ CGH C +CL E + +CP DQ ++ K+Y D E + ++ L +RC ++GC W+G L+ L HL +C ++ CPN C + R L H Q DCPKR ++C+F C A ++ + A H C + P+PCPN C + RE+L HL+ C CPF E GC + K + H+ + HL +MC ++++ + E+ + +E L LIWKI +Y + EAK FS F T ++GYK+ +S L G+G G H S++I + G +D+LL WPF+ R+TF+L+DQ DP K +V T P+ +N P R + D ++ FG KF+ + +Y+RDDA+FI+A V+ I
Sbjct: 5 DYKFLEKPKRRLLCPLCGKPMREPVQVSTCGHRFCDTCLQEFLSEGVFKCPEDQLPLDYAKIYPDPELEVQVLGLAIRCIHSEEGCRWSGPLRHLQGHLNTCSFNVVPCPNRCPAKLSRRDLPAHLQHDCPKRRLKCEFCGCDFSGEAYESHEGVCPQESVYCENKCGARMMRRLLAQHATSECPKRTQPCAYCTKEFVYDTIQSHQYQCPRLPVPCPNQCGVGTVAREDLPTHLKDSCSTAFVLCPFKESGCKHRCPKLAMGRHVEESVKPHLAMMC--------------ALVSRQRQELQELRRELEELSIGSDGVLIWKIGSYGRRLQEAKAKPNLECFSPAFYTHKYGYKLQVSAFLNGNGSGEGTHLSIYIRVLPGAFDNLLEWPFARRVTFSLLDQ-SDPGLAKPQHVTETFHPDPNWKNFQKPGTWRGSLDESSLGFGYPKFISHQDIRKRNYVRDDAVFIRASVELPRKI 468
BLAST of TNF receptor-associated factor 4 vs. Ensembl Mouse
Match: Traf2 (TNF receptor-associated factor 2 [Source:MGI Symbol;Acc:MGI:101835]) HSP 1 Score: 198.749 bits (504), Expect = 3.190e-56 Identity = 148/483 (30.64%), Postives = 210/483 (43.48%), Query Frame = 1
Query: 523 LEKKYACVVCDQVLRYPVQFDECGHHCCSSCLPELMRVAPR----CPIDQCH------IERDKVYVDKEFQKEIDNLGVRCSFYQKGCIWTGVLKEL-SNHLESCLHRMITCPNNCNVEFEIRFLEKHKQDDCPKRIIQCQFCEASLIAEVEANHLKVCNKFPIPCPNGCKKKEILRENLAEHLESKCVKQEQDCPFSEYGCDFKGKK--------KRVREHLN--------------------------------------------DDFVSHLTLMCEAIKENTRI----VEEQSKIITQYQTEVGT-------FEKRIESLE-KLYGPQLIWKIDNYQEKFNEAKTGKKTTIFSAPFMTSRFGYKMALSVCLYGDGKARGKHFSLFICICKGDYDSLLLWPFSHRITFTLIDQCQDPEARKNVVYTVKPNTCKENAPFLGRPTTDRNASFGAQKFVELDVLNTLD-YIRDDAIFIKAQVD 1743
LE KY C C +LR P Q +CGH CS CL ++ P+ C + + +E + D ++E+++L C GC W G LKE S H C + CP C + E H + +CPKR + CQ C A H +VC KFP+ C +GC KK+I RE +H+ + C K C F GC + +R+REHL + V + + EA R+ +E S + Q + +G E+++ LE Y IWKI ++ K EA G+ IFS F TSR+GYKM L V L GDG RG H SLF + KG D+LL WPF+ ++T L+D R++V+ +P+ + RP +D N + G F + + + Y+RDDAIFIKA VD
Sbjct: 28 LEAKYLCSACKNILRRPFQ-AQCGHRYCSFCLTSILSSGPQNCAACVYEGLYEEGISILESSSAFPDNAARREVESLPAVCP--NDGCTWKGTLKEYESCHEGLCPFLLTECPA-CKGLVRLSEKEHHTEQECPKRSLSCQHCRAPCSHVDLEVHYEVCPKFPLTC-DGCGKKKIPRETFQDHVRA-CSKCRVLCRFHTVGCSEMVETENLQDHELQRLREHLALLLSSFLEAQASPGTLNQVGPELLQRCQILEQKIATFENIVCVLNREVERVAVTAEACSRQHRLDQDKIEALSNKVQQLERSIGLKDLAMADLEQKVSELEVSTYDGVFIWKISDFTRKRQEAVAGRTPAIFSPAFYTSRYGYKMCLRVYLNGDGTGRGTHLSLFFVVMKGPNDALLQWPFNQKVTLMLLDH----NNREHVIDAFRPDVTSSS---FQRPVSDMNIASGCPLFCPVSKMEAKNSYVRDDAIFIKAIVD 497
BLAST of TNF receptor-associated factor 4 vs. Ensembl Mouse
Match: Traf2 (TNF receptor-associated factor 2 [Source:MGI Symbol;Acc:MGI:101835]) HSP 1 Score: 196.438 bits (498), Expect = 2.466e-55 Identity = 149/490 (30.41%), Postives = 210/490 (42.86%), Query Frame = 1
Query: 523 LEKKYACVVCDQVLRYPVQFDECGHHCCSSCLPELMRVA-----------PRCPIDQCH------IERDKVYVDKEFQKEIDNLGVRCSFYQKGCIWTGVLKEL-SNHLESCLHRMITCPNNCNVEFEIRFLEKHKQDDCPKRIIQCQFCEASLIAEVEANHLKVCNKFPIPCPNGCKKKEILRENLAEHLESKCVKQEQDCPFSEYGCDFKGKK--------KRVREHLN--------------------------------------------DDFVSHLTLMCEAIKENTRI----VEEQSKIITQYQTEVGT-------FEKRIESLE-KLYGPQLIWKIDNYQEKFNEAKTGKKTTIFSAPFMTSRFGYKMALSVCLYGDGKARGKHFSLFICICKGDYDSLLLWPFSHRITFTLIDQCQDPEARKNVVYTVKPNTCKENAPFLGRPTTDRNASFGAQKFVELDVLNTLD-YIRDDAIFIKAQVD 1743
LE KY C C +LR P Q +CGH CS CL ++R A C + + +E + D ++E+++L C GC W G LKE S H C + CP C + E H + +CPKR + CQ C A H +VC KFP+ C +GC KK+I RE +H+ + C K C F GC + +R+REHL + V + + EA R+ +E S + Q + +G E+++ LE Y IWKI ++ K EA G+ IFS F TSR+GYKM L V L GDG RG H SLF + KG D+LL WPF+ ++T L+D R++V+ +P+ + RP +D N + G F + + + Y+RDDAIFIKA VD
Sbjct: 28 LEAKYLCSACKNILRRPFQ-AQCGHRYCSFCLTSILRCASILSSSGPQNCAACVYEGLYEEGISILESSSAFPDNAARREVESLPAVCP--NDGCTWKGTLKEYESCHEGLCPFLLTECPA-CKGLVRLSEKEHHTEQECPKRSLSCQHCRAPCSHVDLEVHYEVCPKFPLTC-DGCGKKKIPRETFQDHVRA-CSKCRVLCRFHTVGCSEMVETENLQDHELQRLREHLALLLSSFLEAQASPGTLNQVGPELLQRCQILEQKIATFENIVCVLNREVERVAVTAEACSRQHRLDQDKIEALSNKVQQLERSIGLKDLAMADLEQKVSELEVSTYDGVFIWKISDFTRKRQEAVAGRTPAIFSPAFYTSRYGYKMCLRVYLNGDGTGRGTHLSLFFVVMKGPNDALLQWPFNQKVTLMLLDH----NNREHVIDAFRPDVTSSS---FQRPVSDMNIASGCPLFCPVSKMEAKNSYVRDDAIFIKAIVD 504
BLAST of TNF receptor-associated factor 4 vs. Ensembl Mouse
Match: Traf6 (TNF receptor-associated factor 6 [Source:MGI Symbol;Acc:MGI:108072]) HSP 1 Score: 160.999 bits (406), Expect = 2.373e-42 Identity = 128/463 (27.65%), Postives = 202/463 (43.63%), Query Frame = 1
Query: 502 DVIFIDPLEKKYACVVCDQVLRYPVQFDECGHHCCSSCLPELMRVAP-RCPIDQCHIERDKVYVDKEFQKEIDNLGVRCSFYQKGCIWTGVLKELSNHLESCLHRMITCPNNCNVEFEIRFLEKHKQDDCPKRIIQCQFCEASLIAEVEANHLKVCNKFPIPCPNGCKKKEILRENLAEHLESKCVKQEQDCPFSEYGCDFKGKKKRVREHLNDDFVSHLTLMCEA--------------------------------------------IKENTRIVEEQSKIITQYQTEVGTFEKRIESLEKLYGPQL-IWKIDNYQEKFNEAKTGKKTTIFSAPFMTSRFGYKMALSVCLYGDGKAR-GKHFSLFICICKGDYDSLLLWPFSHRITFTLIDQCQDPEARKN--VVYTVKPNTCKENAPFLGRPTTDRNA-SFGAQKFVELDVLNTLDYIRDDAIFIKAQV 1740
DV F PLE KY C +C LR VQ CGH C +C+ + +R A +CP+D + ++++ D ++EI +L V+C KGC+ L+ L +H C ++ CP C F+ + H +DCP+R + C C S+ E + H + C I C C ++RE + H + C C FS +GC K ++ + HL ++ H+ L+ +A I+E T +E QS + + + + T E ++ +E + IWKI N+ + + I S F T R GYK+ + + L R + SLF+ +G+YDS L WPF I T++DQ + R+N V KP RPT RN FG F+ L+ L +I+DD + ++ +V
Sbjct: 57 DVEFDPPLESKYECPICLMALREAVQ-TPCGHRFCKACIIKSIRDAGHKCPVDNEILLENQLFPDNFAKREILSLTVKCP--NKGCLQKMELRHLEDHQVHCEFALVNCPQ-CQRPFQKCQVNTHIIEDCPRRQVSCVNCAVSMAYEEKEIHDQSCPLANIIC-EYCGTI-LIREQMPNHYDLDCPTAPIPCTFSVFGCHEKMQRNHLARHLQENTQLHMRLLAQAVHNVNLALRPCDAASPSRGCRPEDPNYEETIKQLESRLVRQDHQIRELTAKMETQSMYVGELKRTIRTLEDKVAEMEAQQCNGIYIWKIGNFGMHLKSQEEERPVVIHSPGFYTGRPGYKLCMRLHLQLPTAQRCANYISLFVHTMQGEYDSHLPWPFQGTIRLTILDQ-SEALIRQNHEEVMDAKPELLA-----FQRPTIPRNPKGFGYVTFMHLEALRQGTFIKDDTLLVRCEV 507
BLAST of TNF receptor-associated factor 4 vs. Ensembl Mouse
Match: Traf3 (TNF receptor-associated factor 3 [Source:MGI Symbol;Acc:MGI:108041]) HSP 1 Score: 152.91 bits (385), Expect = 2.020e-39 Identity = 145/553 (26.22%), Postives = 230/553 (41.59%), Query Frame = 1
Query: 412 SSVSIDSVGIFHNQIKNPPIITNSNN---------QNDVDVIFIDPLEKKYACVVCDQVLRYPVQFDECGHHCCSSCLPELMRVA-PRCPIDQCHIERDKVYVDKEFQKEIDNLGVRCSFYQKG-----------------------------CIWTGVLKELSNHLE-SCLHR---------------------------MITCPNNCNVEFEIRF--------------------LEKHKQDDCPKRIIQCQFCEASLIAEVEANHLKVCNKFPIPCPNGCKKKEILRENLAEHLESKCVKQEQDCPFSEYGCDFKGKKKRVREHLNDDFVSHLTLMCEAIKE-------------NTRIVEEQ----SKIITQYQTEVGTFEKRIESLEKL-YGPQLIWKIDNYQEKFNEAKTGKKTTIFSAPFMTSRFGYKMALSVCLYGDGKARGKHFSLFICICKGDYDSLLLWPFSHRITFTLIDQCQDPEARKNVVYTVKPNTCKENAPFLGRPTTDRNASFGAQKFVELDVLNTLDYIRDDAIFIKAQVDCDEM 1755
SS +D+ G NPP+ + Q F+ +E KY C C VL P Q ECGH C SC+ L+ + P+C Q I +DKV+ D ++EI L V C +G C + K+L +H+E +C +R +++CP+ C+V+ +R L K + K++ Q +++ H ++C+ F I ++KE+LR N ++ L + V Q E + + ++ E D S + + + E NT ++E Q ++++ + + + R + LE Y LIWKI +Y+ + EA GK +++S PF T FGYKM V L GDG +G H SLF I +G+YD+LL WPF ++T L+DQ +R+++ KP+ N+ +PT + N + G FV VL YI+DD IFIK VD ++
Sbjct: 3 SSKKMDAAGTLQ---PNPPLKLQPDRGAGSVLVPEQGGYKEKFVKTVEDKYKCEKCRLVLCNPKQ-TECGHRFCESCMAALLSSSSPKCTACQESIIKDKVFKDNCCKREILALQVYCRNEGRGCAEQLTLGHLLVHLKNECQFEELPCLRADCKEKVLRKDLRDHVEKACKYREATCSHCKSQVPMIKLQKHEDTDCPCVVVSCPHKCSVQTLLRSEGTNQQIKAHEASSAVQHVNLLKEWSNSLEKKVSLLQNESVEKNKSIQSLHNQICS-FEIEIE---RQKEMLRNNESKILHLQRVIDSQAEKLKELDKEIRPFRQNWEE--ADSMKSSVESLQNRVTELESVDKSAGQAARNTGLLESQLSRHDQMLSVHDIRLADMDLRFQVLETASYNGVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVTLMLMDQ---GSSRRHLGDAFKPDP---NSSSFKKPTGEMNIASGCPVFVAQTVLENGTYIKDDTIFIKVIVDTSDL 539
BLAST of TNF receptor-associated factor 4 vs. UniProt/SwissProt
Match: sp|Q61382|TRAF4_MOUSE (TNF receptor-associated factor 4 OS=Mus musculus OX=10090 GN=Traf4 PE=1 SV=2) HSP 1 Score: 245.358 bits (625), Expect = 4.475e-73 Identity = 143/479 (29.85%), Postives = 222/479 (46.35%), Query Frame = 1
Query: 502 DVIFIDPLEKKYACVVCDQVLRYPVQFDECGHHCCSSCLPELMRVAP-RCPIDQCHIERDKVYVDKEFQKEIDNLGVRCSFYQKGCIWTGVLKELSNHLESCLHRMITCPNNCNVEFEIRFLEKHKQDDCPKRIIQCQF---------------------------CEASLIAEVEANHLKV---------------------------CNKFPIPCPNGCKKKEILRENLAEHLESKCVKQEQDCPFSEYGCDFKGKKKRVREHLNDDFVSHLTLMCEAIKENTRIVEEQSKIITQYQTEVGTFEKRIESLEKLYGPQLIWKIDNYQEKFNEAKTGKKTTIFSAPFMTSRFGYKMALSVCLYGDGKARGKHFSLFICICKGDYDSLLLWPFSHRITFTLIDQCQDPEARK--NVVYTVKPNTCKEN--APFLGRPTTDRNA-SFGAQKFVELDVLNTLDYIRDDAIFIKAQVDCDEMI 1758
D F++ +++ C +C + +R PVQ CGH C +CL E + +CP DQ ++ K+Y D E + ++ L +RC ++GC W+G L+ L HL +C ++ CPN C + R L H Q DCPKR ++C+F C A ++ + A H C + P+PCPN C + RE+L HL+ C CPF E GC + K + H+ + HL +MC ++++ + E+ + +E L LIWKI +Y + EAK FS F T ++GYK+ +S L G+G G H S++I + G +D+LL WPF+ R+TF+L+DQ DP K +V T P+ +N P R + D ++ FG KF+ + +Y+RDDA+FI+A V+ I
Sbjct: 5 DYKFLEKPKRRLLCPLCGKPMREPVQVSTCGHRFCDTCLQEFLSEGVFKCPEDQLPLDYAKIYPDPELEVQVLGLAIRCIHSEEGCRWSGPLRHLQGHLNTCSFNVVPCPNRCPAKLSRRDLPAHLQHDCPKRRLKCEFCGCDFSGEAYESHEGVCPQESVYCENKCGARMMRRLLAQHATSECPKRTQPCAYCTKEFVYDTIQSHQYQCPRLPVPCPNQCGVGTVAREDLPTHLKDSCSTAFVLCPFKESGCKHRCPKLAMGRHVEESVKPHLAMMC--------------ALVSRQRQELQELRRELEELSIGSDGVLIWKIGSYGRRLQEAKAKPNLECFSPAFYTHKYGYKLQVSAFLNGNGSGEGTHLSIYIRVLPGAFDNLLEWPFARRVTFSLLDQ-SDPGLAKPQHVTETFHPDPNWKNFQKPGTWRGSLDESSLGFGYPKFISHQDIRKRNYVRDDAVFIRASVELPRKI 468
BLAST of TNF receptor-associated factor 4 vs. UniProt/SwissProt
Match: sp|Q9BUZ4|TRAF4_HUMAN (TNF receptor-associated factor 4 OS=Homo sapiens OX=9606 GN=TRAF4 PE=1 SV=1) HSP 1 Score: 226.483 bits (576), Expect = 4.899e-66 Identity = 136/479 (28.39%), Postives = 214/479 (44.68%), Query Frame = 1
Query: 502 DVIFIDPLEKKYACVVCDQVLRYPVQFDECGHHCCSSCLPELMRVAP-RCPIDQCHIERDKVYVDKEFQKEIDNLGVRCSFYQKGCIWTGVLK---------------------------ELSNHLES---------------------------CLHRMITCPNNCNVEFEIRFLEKHKQDDCPKRIIQCQFCEASLIAEVEANHLKVCNKFPIPCPNGCKKKEILRENLAEHLESKCVKQEQDCPFSEYGCDFKGKKKRVREHLNDDFVSHLTLMCEAIKENTRIVEEQSKIITQYQTEVGTFEKRIESLEKLYGPQLIWKIDNYQEKFNEAKTGKKTTIFSAPFMTSRFGYKMALSVCLYGDGKARGKHFSLFICICKGDYDSLLLWPFSHRITFTLIDQCQDPEARK--NVVYTVKPNTCKEN--APFLGRPTTDRNA-SFGAQKFVELDVLNTLDYIRDDAIFIKAQVDCDEMI 1758
D F++ +++ C +C + +R PVQ CGH C +CL E + +CP DQ ++ K+Y D E + ++ L +RC ++GC W+G L+ +L HL+ C + C N C R L +H +CPKR C +C + + +H C + P+ CPN C + RE+L HL+ C CPF + GC + K + H+ + HL +MC ++++ + E+ + +E L LIWKI +Y + EAK FS F T ++GYK+ +S L G+G G H SL+I + G +D+LL WPF+ R+TF+L+DQ DP K +V T P+ +N P R + D ++ FG KF+ + +Y+RDDA+FI+A V+ I
Sbjct: 5 DYKFLEKPKRRLLCPLCGKPMREPVQVSTCGHRFCDTCLQEFLSEGVFKCPEDQLPLDYAKIYPDPELEVQVLGLPIRCIHSEEGCRWSGPLRHLQGHLNTCSFNVIPCPNRCPMKLSRRDLPAHLQHDCPKRRLKCEFCGCDFSGEAYESHEGMCPQESVYCENKCGARMMRRLLAQHATSECPKRTQPCTYCTKEFVFDTIQSHQYQCPRLPVACPNQCGVGTVAREDLPGHLKDSCNTALVLCPFKDSGCKHRCPKLAMARHVEESVKPHLAMMC--------------ALVSRQRQELQELRRELEELSVGSDGVLIWKIGSYGRRLQEAKAKPNLECFSPAFYTHKYGYKLQVSAFLNGNGSGEGTHLSLYIRVLPGAFDNLLEWPFARRVTFSLLDQ-SDPGLAKPQHVTETFHPDPNWKNFQKPGTWRGSLDESSLGFGYPKFISHQDIRKRNYVRDDAVFIRAAVELPRKI 468
BLAST of TNF receptor-associated factor 4 vs. UniProt/SwissProt
Match: sp|Q12933|TRAF2_HUMAN (TNF receptor-associated factor 2 OS=Homo sapiens OX=9606 GN=TRAF2 PE=1 SV=2) HSP 1 Score: 201.83 bits (512), Expect = 1.691e-56 Identity = 153/484 (31.61%), Postives = 221/484 (45.66%), Query Frame = 1
Query: 523 LEKKYACVVCDQVLRYPVQFDECGHHCCSSCLPELMRVAPRCPIDQCH----------IERDKVYVDKEFQKEIDNLGVRCSFYQKGCIWTGVLKEL-SNHLESCLHRMITCPNNCNVEFEIRFLEKHKQDDCPKRIIQCQFCEASLI-AEVEANHLKVCNKFPIPCPNGCKKKEILRENLAEHLESKCVKQEQDCPFSEYGC--DFKGKKKR------VREHL----------------NDDFVSHLTLMCEAIKENTRIVE--------------------------EQSKI------ITQYQTEVGTFEKRIESLEK--------LYGPQLIWKIDNYQEKFNEAKTGKKTTIFSAPFMTSRFGYKMALSVCLYGDGKARGKHFSLFICICKGDYDSLLLWPFSHRITFTLIDQCQDPEARKNVVYTVKPNTCKENAPFLGRPTTDRNASFGAQKFVELDVLNTLD-YIRDDAIFIKAQVD 1743
LE KY C C VLR P Q +CGH CS CL ++ P+ H +E + D ++E+++L C GC W G LKE S H C + CP C + E+H + +CP+R + C+ C A A+V+A+H +VC KFP+ C +GC KK+I RE +H+++ C K C F GC +G+K++ +REHL S L CE++++ T E +Q KI + Q + +G + + LE+ Y IWKI ++ K EA G+ IFS F TSR+GYKM L + L GDG RG H SLF + KG D+LL WPF+ ++T L+DQ R++V+ +P+ + RP D N + G F + + + Y+RDDAIFIKA VD
Sbjct: 28 LEAKYLCSACRNVLRRPFQ-AQCGHRYCSFCLASILSSGPQNCAACVHEGIYEEGISILESSSAFPDNAARREVESLPAVCP--SDGCTWKGTLKEYESCHEGRCPLMLTECPA-CKGLVRLGEKERHLEHECPERSLSCRHCRAPCCGADVKAHH-EVCPKFPLTC-DGCGKKKIPREKFQDHVKT-CGKCRVPCRFHAIGCLETVEGEKQQEHEVQWLREHLAMLLSSVLEAKPLLGDQSHAGSELLQRCESLEKKTATFENIVCVLNREVERVAMTAEACSRQHRLDQDKIEALSSKVQQLERSIGLKDLAMADLEQKVLEMEASTYDGVFIWKISDFARKRQEAVAGRIPAIFSPAFYTSRYGYKMCLRIYLNGDGTGRGTHLSLFFVVMKGPNDALLRWPFNQKVTLMLLDQ----NNREHVIDAFRPDVTSSS---FQRPVNDMNIASGCPLFCPVSKMEAKNSYVRDDAIFIKAIVD 497
BLAST of TNF receptor-associated factor 4 vs. UniProt/SwissProt
Match: sp|P39429|TRAF2_MOUSE (TNF receptor-associated factor 2 OS=Mus musculus OX=10090 GN=Traf2 PE=1 SV=1) HSP 1 Score: 198.749 bits (504), Expect = 2.231e-55 Identity = 148/483 (30.64%), Postives = 210/483 (43.48%), Query Frame = 1
Query: 523 LEKKYACVVCDQVLRYPVQFDECGHHCCSSCLPELMRVAPR----CPIDQCH------IERDKVYVDKEFQKEIDNLGVRCSFYQKGCIWTGVLKEL-SNHLESCLHRMITCPNNCNVEFEIRFLEKHKQDDCPKRIIQCQFCEASLIAEVEANHLKVCNKFPIPCPNGCKKKEILRENLAEHLESKCVKQEQDCPFSEYGCDFKGKK--------KRVREHLN--------------------------------------------DDFVSHLTLMCEAIKENTRI----VEEQSKIITQYQTEVGT-------FEKRIESLE-KLYGPQLIWKIDNYQEKFNEAKTGKKTTIFSAPFMTSRFGYKMALSVCLYGDGKARGKHFSLFICICKGDYDSLLLWPFSHRITFTLIDQCQDPEARKNVVYTVKPNTCKENAPFLGRPTTDRNASFGAQKFVELDVLNTLD-YIRDDAIFIKAQVD 1743
LE KY C C +LR P Q +CGH CS CL ++ P+ C + + +E + D ++E+++L C GC W G LKE S H C + CP C + E H + +CPKR + CQ C A H +VC KFP+ C +GC KK+I RE +H+ + C K C F GC + +R+REHL + V + + EA R+ +E S + Q + +G E+++ LE Y IWKI ++ K EA G+ IFS F TSR+GYKM L V L GDG RG H SLF + KG D+LL WPF+ ++T L+D R++V+ +P+ + RP +D N + G F + + + Y+RDDAIFIKA VD
Sbjct: 28 LEAKYLCSACKNILRRPFQ-AQCGHRYCSFCLTSILSSGPQNCAACVYEGLYEEGISILESSSAFPDNAARREVESLPAVCP--NDGCTWKGTLKEYESCHEGLCPFLLTECPA-CKGLVRLSEKEHHTEQECPKRSLSCQHCRAPCSHVDLEVHYEVCPKFPLTC-DGCGKKKIPRETFQDHVRA-CSKCRVLCRFHTVGCSEMVETENLQDHELQRLREHLALLLSSFLEAQASPGTLNQVGPELLQRCQILEQKIATFENIVCVLNREVERVAVTAEACSRQHRLDQDKIEALSNKVQQLERSIGLKDLAMADLEQKVSELEVSTYDGVFIWKISDFTRKRQEAVAGRTPAIFSPAFYTSRYGYKMCLRVYLNGDGTGRGTHLSLFFVVMKGPNDALLQWPFNQKVTLMLLDH----NNREHVIDAFRPDVTSSS---FQRPVSDMNIASGCPLFCPVSKMEAKNSYVRDDAIFIKAIVD 497
BLAST of TNF receptor-associated factor 4 vs. UniProt/SwissProt
Match: sp|Q6IWL4|TRAF6_DANRE (TNF receptor-associated factor 6 OS=Danio rerio OX=7955 GN=traf6 PE=1 SV=2) HSP 1 Score: 172.17 bits (435), Expect = 2.727e-45 Identity = 132/501 (26.35%), Postives = 219/501 (43.71%), Query Frame = 1
Query: 442 FHNQIKNPPIITNSN----NQNDVDVIFIDPLEKKYACVVCDQVLRYPVQFDECGHHCCSSCLPELMR-VAPRCPIDQCHIERDKVYVDKEFQKEIDNLGVRCSFYQKGCIWTGVLKELSNHLESCLHRMITCPNNCNVEFEIRFLEKHKQDDCPKRIIQCQFCEASLIAEVEANHLKVCNKFPIPCPNGCKKKEILRENLAEHLESKCVKQEQDCPFSEYGCDFKGKKKRVREHLNDDFVSHLTLMCEAIKENT---------------------------------------RIVEEQSKIITQYQ-------------TEVGTFEKRIESLE--------KLYGPQLIWKIDNYQEKFNEAKTGKKTTIFSAPFMTSRFGYKMALSVCLYGDGKARGKHF-SLFICICKGDYDSLLLWPFSHRITFTLIDQCQDPEARKNV-VYTVKPNTCKENAPFLGRPTTDRNA-SFGAQKFVELDVLNTLDYIRDDAIFIKAQV 1740
F + +NP I+ S+ +Q DV F PLE KY C +C LR VQ CGH C SC+ + +R +CP+D + ++++ D ++EI +L V+CS + GC L++L HL C CP C I L++HK C +RI+ C C S + V+ NH + C C C + E++R+ LA H ++ C+K C FS +GC K + + +H+ + H+ M E ++ T ++E + +++ Q Q +V +++ SLE + Y +W+++N+ + G+ + S PF T R GYK+ L + L R +F SLF+ +G++DS L WP I ++DQ E + ++ V KP+ RPT RN FG F+ L L ++++D + ++ +V
Sbjct: 34 FLSPTENPSTISVSSSMPPDQQGYDVEFDPPLESKYECPICLMGLRSAVQ-TPCGHRFCDSCIRKSIRDTGQKCPVDNEVLLEEQLFPDNFAKREILSLTVKCSNF--GCSEKMELRQLEKHLSQCRFATAPCP-QCQESVPISHLDEHKSQHCLQRIMTCPDCAGSFVYAVKQNHEQFCPFANTVC-EYC-EMELIRDQLALHCDTDCLKAPVACTFSTFGCREKMTRNELAQHMQEFTQMHMRYMAEFLRSQTLNNCTMPSAAAHLSSDDRGASARSPDSCQCKQELLNLRETVLELEGRLVRQDQQIRELCIHNDTQKNQVTELRRKLVSLEESTRELEAQQYQGIYVWRVENFSHHLRNQEAGQPIVLHSPPFYTGRPGYKLCLRLHLQTPSAPRCSNFISLFVHTMQGEFDSQLSWPLQGTIRLAVLDQV---EGQHHIEVMETKPDL-----QAFQRPTVMRNPKGFGYVTFLHLQALRQRGFVKEDVLLVRCEV 520
BLAST of TNF receptor-associated factor 4 vs. TrEMBL
Match: A0A267ELC7 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig027678g1 PE=4 SV=1) HSP 1 Score: 589.726 bits (1519), Expect = 0.000e+0 Identity = 264/420 (62.86%), Postives = 335/420 (79.76%), Query Frame = 1
Query: 496 DVDVIFIDPLEKKYACVVCDQVLRYPVQFDECGHHCCSSCLPELMRVAPRCPIDQCHIERDKVYVDKEFQKEIDNLGVRCSFYQKGCIWTGVLKELSNHLESCLHRMITCPNNCNVEFEIRFLEKHKQDDCPKRIIQCQFCEASLIAEVEANHLKVCNKFPIPCPNGCKKKEILRENLAEHLESKCVKQEQDCPFSEYGCDFKGKKKRVREHLNDDFVSHLTLMCEAIKENTRIVEEQSKIITQYQTEVGTFEKRIESLEKLYGPQLIWKIDNYQEKFNEAKTGKKTTIFSAPFMTSRFGYKMALSVCLYGDGKARGKHFSLFICICKGDYDSLLLWPFSHRITFTLIDQCQDPEARKNVVYTVKPNTCKENAPFLGRPTTDRNASFGAQKFVELDVLNTLDYIRDDAIFIKAQVDCDEM 1755
+V+V+F++ L+KKY C VC QVLRYPVQF+ECGH CCSSCLP+L+RVAPRCP+DQ I++DKVYVDK FQKE DNLGV+CSF +GC WTG+L EL H+E C M TCP C VEFE RFLEKH+ DDCPKR I CQFCE LIAE EA HL++C KF +PCPN CK++E+ RE L EHLE++C+KQ+ +CPF+ YGC F GKKK ++EH+ ++H+ ++C A+K+ + E Q K I + + ++ E+RI LE LYGPQLIWKIDNY+EK EAK+GKK+TIFS PF+T+R GYK+A+S CLYGDGK+RGK+ SLF+CICKGD D LL WPF+++ITF LIDQC+D AR+N+VY VKPNTCKEN PFLGRP +RNASFGA +F EL+V+ TLDYI+DD ++IK +VDC++M
Sbjct: 70 EVEVVFLEQLDKKYECPVCGQVLRYPVQFEECGHRCCSSCLPDLLRVAPRCPLDQVAIDKDKVYVDKAFQKETDNLGVKCSFSARGCPWTGLLLELMAHMEGCDRMMTTCPMRCGVEFEKRFLEKHRNDDCPKREIHCQFCEIRLIAENEAEHLEICPKFLVPCPNKCKRREVARERLTEHLENECMKQDLNCPFASYGCQFTGKKKAMKEHVAAKQLNHMEILCAAVKQGDKNRENQDKAIQEMEKKMLGIERRINGLENLYGPQLIWKIDNYEEKLAEAKSGKKSTIFSPPFLTNRHGYKLAMSACLYGDGKSRGKYMSLFVCICKGDNDPLLAWPFAYKITFHLIDQCEDVAARRNIVYVVKPNTCKENRPFLGRPVGERNASFGAARFAELEVIGTLDYIKDDTMYIKVEVDCEDM 489
BLAST of TNF receptor-associated factor 4 vs. TrEMBL
Match: A0A267DPF2 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig027678g2 PE=4 SV=1) HSP 1 Score: 587.8 bits (1514), Expect = 0.000e+0 Identity = 263/420 (62.62%), Postives = 335/420 (79.76%), Query Frame = 1
Query: 496 DVDVIFIDPLEKKYACVVCDQVLRYPVQFDECGHHCCSSCLPELMRVAPRCPIDQCHIERDKVYVDKEFQKEIDNLGVRCSFYQKGCIWTGVLKELSNHLESCLHRMITCPNNCNVEFEIRFLEKHKQDDCPKRIIQCQFCEASLIAEVEANHLKVCNKFPIPCPNGCKKKEILRENLAEHLESKCVKQEQDCPFSEYGCDFKGKKKRVREHLNDDFVSHLTLMCEAIKENTRIVEEQSKIITQYQTEVGTFEKRIESLEKLYGPQLIWKIDNYQEKFNEAKTGKKTTIFSAPFMTSRFGYKMALSVCLYGDGKARGKHFSLFICICKGDYDSLLLWPFSHRITFTLIDQCQDPEARKNVVYTVKPNTCKENAPFLGRPTTDRNASFGAQKFVELDVLNTLDYIRDDAIFIKAQVDCDEM 1755
+V+V+F++ L+KKY C VC QVLRYPVQF+ECGH CCSSCLP+L+RVAPRCP+DQ I+++KVYVDK FQKE DNLGV+CSF +GC WTG+L EL H+E C M TCP C VEFE RFLEKH+ DDCPKR I CQFCE LIAE EA HL++C KF +PCPN CK++E+ RE L EHLE++C+KQ+ +CPF+ YGC F GKKK ++EH+ ++H+ ++C A+K+ + E Q K I + + ++ E+RI LE LYGPQLIWKIDNY+EK EAK+GKK+TIFS PF+T+R GYK+A+S CLYGDGK+RGK+ SLF+CICKGD D LL WPF+++ITF LIDQC+D AR+N+VY VKPNTCKEN PFLGRP +RNASFGA +F EL+V+ TLDYI+DD ++IK +VDC++M
Sbjct: 70 EVEVVFLEQLDKKYECPVCGQVLRYPVQFEECGHRCCSSCLPDLLRVAPRCPLDQVAIDKEKVYVDKAFQKETDNLGVKCSFSARGCPWTGLLLELMAHMEGCDRMMTTCPMRCGVEFEKRFLEKHRNDDCPKREIHCQFCEIRLIAENEAEHLEICPKFLVPCPNKCKRREVARERLTEHLENECMKQDLNCPFASYGCQFTGKKKAMKEHVAAKQLNHMEILCAAVKQGDKNRENQDKAIQEMEKKMLGIERRINGLENLYGPQLIWKIDNYEEKLAEAKSGKKSTIFSPPFLTNRHGYKLAMSACLYGDGKSRGKYMSLFVCICKGDNDPLLAWPFAYKITFHLIDQCEDVAARRNIVYVVKPNTCKENRPFLGRPVGERNASFGAARFAELEVIGTLDYIKDDTMYIKVEVDCEDM 489
BLAST of TNF receptor-associated factor 4 vs. TrEMBL
Match: A0A1I8I4E9 (Uncharacterized protein OS=Macrostomum lignano OX=282301 PE=4 SV=1) HSP 1 Score: 584.334 bits (1505), Expect = 0.000e+0 Identity = 254/423 (60.05%), Postives = 333/423 (78.72%), Query Frame = 1
Query: 496 DVDVIFIDPLEKKYACVVCDQVLRYPVQFDECGHHCCSSCLPELMRVAPRCPIDQCHIERDKVYVDKEFQKEIDNLGVRCSFYQKGCIWTGVLKELSNHLESCLHRMITCPNNCNVEFEIRFLEKHKQDDCPKRIIQCQFCEASLIAEVEANHLKVCNKFPIPCPNGCKKKEILRENLAEHLESKCVKQEQDCPFSEYGCDFKGKKKRVREHLNDDFVSHLTLMCEAIKENTRIVEEQSKIITQYQTEVGTFEKRIESLEKLYGPQLIWKIDNYQEKFNEAKTGKKTTIFSAPFMTSRFGYKMALSVCLYGDGKARGKHFSLFICICKGDYDSLLLWPFSHRITFTLIDQCQDPEARKNVVYTVKPNTCKENAPFLGRPTTDRNASFGAQKFVELDVLNTLDYIRDDAIFIKAQVDCDEMINI 1764
+VDV+F++ L+KKY C VC QVLRYPVQF+ECGH CCSSCLP+L+RVAPRCPIDQ I++DKVY DK FQKE D+LGV+CSF+++GC WTGVL EL +H+E C + TCP C VEF+ RFLEKH+ +DCPKR IQCQFCE L+AE EA HL+ C KF +PCPN CKKKE+ RE + EHLE++C++Q+ CPFS YGCDF G+KK+++EH+ + ++H+ ++C A+K+ + E+Q K I + + ++ E+R+ LE L+GPQL+W+IDNYQEK EAK GKK TIFS PF+T+R GYK+ALS CLYGDGK RG++ SLF CICKG+ D+LL WPF++++TF LIDQC+D ARKN+VYTV PN CKEN PFLGRP +RNASFGA +F ELD + LDYI+DD +++K VD + ++ +
Sbjct: 1083 EVDVVFLESLDKKYECPVCGQVLRYPVQFEECGHRCCSSCLPDLLRVAPRCPIDQQTIDKDKVYADKAFQKETDSLGVKCSFFERGCNWTGVLSELMSHIEGCDRMLTTCPMRCGVEFQKRFLEKHRLEDCPKRDIQCQFCEIGLVAEQEAGHLETCPKFLVPCPNKCKKKEVAREMMQEHLENECMRQDLCCPFSTYGCDFSGRKKQLKEHIAEKQLNHMEILCSAVKQGDKNQEKQQKQILEMEKKLVGVERRVGGLENLFGPQLVWRIDNYQEKLAEAKAGKKATIFSPPFLTNRHGYKLALSACLYGDGKFRGQYMSLFACICKGENDALLAWPFAYKLTFQLIDQCEDVSARKNIVYTVTPNPCKENRPFLGRPLGERNASFGAARFAELDAIGKLDYIKDDTMYVKVTVDLENLLPL 1505
BLAST of TNF receptor-associated factor 4 vs. TrEMBL
Match: A0A1S3KE24 (TNF receptor-associated factor 4 OS=Lingula unguis OX=7574 GN=LOC106181010 PE=4 SV=1) HSP 1 Score: 575.089 bits (1481), Expect = 0.000e+0 Identity = 270/457 (59.08%), Postives = 344/457 (75.27%), Query Frame = 1
Query: 394 HKNSNLSSVSIDSVGIFHNQIKNPPIITNSNNQNDVDVIFIDPLEKKYACVVCDQVLRYPVQFDECGHHCCSSCLPELMRVAPRCPIDQCHIERDKVYVDKEFQKEIDNLGVRCSFYQKGCIWTGVLKELSNHLESCLHRMITCPNNCNVEFEIRFLEKHKQDDCPKRIIQCQFCEASLIAEVEANHLKVCNKFPIPCPNGCKKKEILRENLAEHLESKCVKQEQDCPFSEYGCDFKGKKKRVREHLNDDFVSHLTLMCEAIKENTRIVEEQSKIITQYQTEVGTFEKRIESLEKLYGPQLIWKIDNYQEKFNEAKTGKKTTIFSAPFMTSRFGYKMALSVCLYGDGKARGKHFSLFICICKGDYDSLLLWPFSHRITFTLIDQCQDPEARKNVVYTVKPNTCKENAPFLGRPTTDRNASFGAQKFVELDVLNTLDYIRDDAIFIKAQVDCDEMINI 1764
H S LSSVS +S G +++ ++++ F +PLEKKY C VC QVLRYP+QFDECGH CCSSCLPEL+RVAPRCPIDQ HI+RDKVYVDK FQ++ID+LGV+CS + C WTG LKEL H E C +++I CP C EFE RFL+KH+ +DCPKR I C+FC+++++ E E HL +C +FPIPCPNGCK+K+I RE +AEH+E C KQ CPF + GC+++ +K++ H+N++ HL+L+ E I + I+++ + + ++ EKRIE LEKLYG Q +WKID+YQEK +EAK G K TIFS PF+TSR GYKMALS CL+GDGKARGK SLF CICKG+ D+LL WPFSHR+TFTL+DQC+DP AR+NV YTVKPNTCK+N PFLGRP+ DRNASFGAQKFVEL+V++TLDYIRDD IFIK VD D+M+ +
Sbjct: 20 HLGSALSSVSRNSNGSL------------VSDRPNLEITFQEPLEKKYECPVCCQVLRYPIQFDECGHRCCSSCLPELLRVAPRCPIDQRHIDRDKVYVDKAFQRDIDHLGVKCSNGR--CKWTGALKELVPHQEDCKYKVIPCPKGCGAEFEKRFLDKHRDEDCPKRKIACEFCKSNILFEEEIEHLNLCKRFPIPCPNGCKRKDIPREEVAEHMEGDCPKQTVPCPFVDCGCEYRCNRKKLTAHVNEEPTMHLSLVAETIARHKEILDKYKLSMEDHTEKLAGMEKRIEGLEKLYGAQFVWKIDSYQEKLDEAKAGTKRTIFSQPFLTSRNGYKMALSACLFGDGKARGKFMSLFACICKGESDALLSWPFSHRVTFTLMDQCEDPAARRNVTYTVKPNTCKDNKPFLGRPSGDRNASFGAQKFVELEVMSTLDYIRDDTIFIKVNVDMDDMVKM 462
BLAST of TNF receptor-associated factor 4 vs. TrEMBL
Match: A0A1I8J068 (Uncharacterized protein OS=Macrostomum lignano OX=282301 PE=4 SV=1) HSP 1 Score: 572.778 bits (1475), Expect = 0.000e+0 Identity = 254/423 (60.05%), Postives = 333/423 (78.72%), Query Frame = 1
Query: 496 DVDVIFIDPLEKKYACVVCDQVLRYPVQFDECGHHCCSSCLPELMRVAPRCPIDQCHIERDKVYVDKEFQKEIDNLGVRCSFYQKGCIWTGVLKELSNHLESCLHRMITCPNNCNVEFEIRFLEKHKQDDCPKRIIQCQFCEASLIAEVEANHLKVCNKFPIPCPNGCKKKEILRENLAEHLESKCVKQEQDCPFSEYGCDFKGKKKRVREHLNDDFVSHLTLMCEAIKENTRIVEEQSKIITQYQTEVGTFEKRIESLEKLYGPQLIWKIDNYQEKFNEAKTGKKTTIFSAPFMTSRFGYKMALSVCLYGDGKARGKHFSLFICICKGDYDSLLLWPFSHRITFTLIDQCQDPEARKNVVYTVKPNTCKENAPFLGRPTTDRNASFGAQKFVELDVLNTLDYIRDDAIFIKAQVDCDEMINI 1764
+VDV+F++ L+KKY C VC QVLRYPVQF+ECGH CCSSCLP+L+RVAPRCPIDQ I++DKVY DK FQKE D+LGV+CSF+++GC WTGVL EL +H+E C + TCP C VEF+ RFLEKH+ +DCPKR IQCQFCE L+AE EA HL+ C KF +PCPN CKKKE+ RE + EHLE++C++Q+ CPFS YGCDF G+KK+++EH+ + ++H+ ++C A+K+ + E+Q K I + + ++ E+R+ LE L+GPQL+W+IDNYQEK EAK GKK TIFS PF+T+R GYK+ALS CLYGDGK RG++ SLF CICKG+ D+LL WPF++++TF LIDQC+D ARKN+VYTV PN CKEN PFLGRP +RNASFGA +F ELD + LDYI+DD +++K VD + ++ +
Sbjct: 45 EVDVVFLESLDKKYECPVCGQVLRYPVQFEECGHRCCSSCLPDLLRVAPRCPIDQQTIDKDKVYADKAFQKETDSLGVKCSFFERGCNWTGVLSELMSHIEGCDRMLTTCPMRCGVEFQKRFLEKHRLEDCPKRDIQCQFCEIGLVAEQEAGHLETCPKFLVPCPNKCKKKEVAREMMQEHLENECMRQDLCCPFSTYGCDFSGRKKQLKEHIAEKQLNHMEILCSAVKQGDKNQEKQQKQILEMEKKLVGVERRVGGLENLFGPQLVWRIDNYQEKLAEAKAGKKATIFSPPFLTNRHGYKLALSACLYGDGKFRGQYMSLFACICKGENDALLAWPFAYKLTFQLIDQCEDVSARKNIVYTVTPNPCKENRPFLGRPLGERNASFGAARFAELDAIGKLDYIKDDTMYVKVTVDLENLLPL 467
BLAST of TNF receptor-associated factor 4 vs. Ensembl Cavefish
Match: traf4a (TNF receptor associated factor 4 [Source:NCBI gene;Acc:103024022]) HSP 1 Score: 268.085 bits (684), Expect = 9.080e-83 Identity = 151/482 (31.33%), Postives = 237/482 (49.17%), Query Frame = 1
Query: 502 DVIFIDPLEKKYACVVCDQVLRYPVQFDECGHHCCSSCLPELMRVAP-RCPIDQCHIERDKVYVDKEFQKEIDNLGVRCSFYQKGCIWTGVLKELSNHLESCLHRMITCPNNCNVEFEIRFLEKHKQDDCPKRIIQCQF---------------------------CEASLIAEVEA---------------------------NHLKVCNKFPIPCPNGCKKKEILRENLAEHLESKCVKQEQDCPFSEYGCDFKGKKKRVREHLNDDFVSHLTLMCEAIKENTRIVEEQSKIITQYQTEVGTFEKRIESLEKLYGPQLIWKIDNYQEKFNEAKTGKKTTIFSAPFMTSRFGYKMALSVCLYGDGKARGKHFSLFICICKGDYDSLLLWPFSHRITFTLIDQCQDPEARK--NVVYTVKPNTCKENAPFLGRPTTDRNA------SFGAQKFVELDVLNTLDYIRDDAIFIKAQVDCDEMI 1758
D F++ ++++ C +C + +R PVQ CGH C +CL E + +CP DQ ++ K+Y D E +++I L +RC ++GC WTG +K+L H +C +I CPN C V+ R L +H Q DCPKR ++C+F C A ++ + A NH C +FP+ CPN C I RE+LA H++ C CPF + GC + K + HL + SHLT+MC ++ + + E+ + +E L + LIWK+++Y K EAK FS PF T R+GYK+ +S L G+G G H S++I + G+YD+LL WPF++++TF+++DQ DP K ++ T P+ +N +P++ RN+ FG KF+ D + +YIRD+AIF+KA ++ + I
Sbjct: 5 DYKFLEKPKRRFQCPLCSKAMREPVQVSTCGHRFCDTCLQEFLSEGVFKCPEDQLPLDYAKIYPDPELEQQILALPIRCIHSEEGCRWTGQMKQLQGHFSTCAFNVIPCPNRCAVKLTRRDLPEHLQHDCPKRKVKCEFCGSEFTGEAFENHQGICPQESVYCENKCGARMMRRLLAQHTMAECPKRTQPCKYCGKEFVYDTIQNHQYHCPRFPVQCPNQCGTPNIAREDLATHVKESCGSALVLCPFKDAGCKHRCPKLAIGRHLEETTKSHLTMMC--------------SLVGRQRQEIIELRREMEELSVSHDGVLIWKLNDYSRKLQEAKLHNNHEFFSPPFYTHRYGYKLQVSAFLNGNGSGEGSHLSIYIRVLPGEYDNLLEWPFAYKVTFSILDQ-SDPSLSKPQHITETFNPDPNWKN---FQKPSSSRNSLDESTLGFGYPKFISHDEIRKRNYIRDNAIFLKASIEIPQKI 468
BLAST of TNF receptor-associated factor 4 vs. Ensembl Cavefish
Match: traf4b (TNF receptor-associated factor 4-like [Source:NCBI gene;Acc:103043275]) HSP 1 Score: 228.794 bits (582), Expect = 1.025e-67 Identity = 142/488 (29.10%), Postives = 232/488 (47.54%), Query Frame = 1
Query: 499 VDVIFIDPLEKKYACVVCDQVLRYPVQFDECGHHCCSSCLPELMRVAP-RCPIDQCHIERDKVYVDKEFQKEIDNLGVRCSFYQKGCIWTGVLKELSNHLESCLHRMITCPN---------------------------NCNVEFE---------------------------IRFLEKHKQDDCPKRIIQCQFCEASLIAEVEANHLKVCNKFPIPCPNGCKKKEILRENLAEHLESKCVKQEQDCPFSEYGCDFKGKKKRVREHLNDDFVSHLTLMCEAIKENTRIVEEQSKIITQYQTEVGTFEKRIESLEKLYGPQLIWKIDNYQEKFNEAKTGKKTT--IFSAPFMTSRFGYKMALSVCLYGDGKARGKHFSLFICICKGDYDSLLLWPFSHRITFTLIDQCQDPEARK--NVVYTVKPNTCKEN--APFLGRPTTDRNAS-------FGAQKFVELDVLNTLDYIRDDAIFIKAQVDCDEMI 1758
+D F++ +++ C +C + +R PVQ CGH C +CL E + +CP DQ ++ K++ D E +++I L +RC ++GC W+ K+L HL +C + +++CPN +C++EF R L +H +C KR + C++C + + +H C +FP+ CPN C I RE+L H++ C CPF E GC ++ K V HL D SHL+L+C ++ + + E+ +R+E L L+WKI +Y + EA+T + +FS F + R GY++ +S L G+G G + S++I + G+YD LL WPF +R+TF+L+DQ DP K ++V + P+ +N P G + R S FG KF+ + + +YIRD+AIFI+A +D + I
Sbjct: 4 LDYKFLERPRRRFLCPLCSKPMREPVQVSTCGHRFCDTCLQEFLSEGVFKCPEDQLPLDYAKIFPDVELEQQILALPIRCIHSEEGCRWSAQNKQLQAHLSACAYNVVSCPNRCSVKLLRRDLLDHLQHDCSKRKLRCDHCSLEFTGEAHERHQDACPEESVYCENKCGARMVRRLLAQHTLSECSKRKLPCKYCNKEFLYDTIQHHQNQCPRFPVQCPNKCGTPGIAREDLMTHVKESCGTAMVFCPFKEAGCKYRCIKPAVPHHLEDATHSHLSLLC--------------GLVNRQRLELRDLRRRVEELSGSQDGVLLWKIPDYCRRLQEARTRTTGSAELFSPAFYSHRHGYRLQVSAFLNGNGSGEGSYLSIYIRVLPGEYDGLLEWPFPYRVTFSLLDQ-SDPALSKPQHIVESFSPDPNWKNFQRPQPGAMGSIRAGSLDESMLGFGYPKFISHEQMRKRNYIRDNAIFIQASIDVVQRI 476
BLAST of TNF receptor-associated factor 4 vs. Ensembl Cavefish
Match: traf2a (TNF receptor-associated factor 2-like [Source:NCBI gene;Acc:103036375]) HSP 1 Score: 189.889 bits (481), Expect = 1.751e-53 Identity = 139/487 (28.54%), Postives = 219/487 (44.97%), Query Frame = 1
Query: 451 QIKNPPIITNSNNQNDVDVIFIDPLEKKYACVVCDQVLRYPVQFDECGHHCCSSCLPELMRVAPRCPIDQCHIERDKVYVDKEFQKEIDNLGVRCSFYQKGCIWTGVLKEL-SNHLESCLHRMITCPNNCNVEFEIRFLEKHKQDDCPKRIIQCQFCEASLIAEVEANHLKVCNKFPIPCPNGCKKKEILRENLAEHLESKCVKQEQDCPFSEYGCDFKGKKKR------VREHLNDDF--------VSHLTLMCEAIK------EN-----TRIVEEQSKIITQY-------QTEVGTFEKRIESLEKLYGPQ----------------------LIWKIDNYQEKFNEAKTGKKTTIFSAPFMTSRFGYKMALSVCLYGDGKARGKHFSLFICICKGDYDSLLLWPFSHRITFTLIDQCQDPEARKNVVYTVKPNTCKENAPFLGRPTTDRNASFGAQKFVELDVLNTLD-YIRDDAIFIKAQVD 1743
Q +PP N I + LE K+ C +C ++LR P Q +CGH R +P + D ++E++ L C +GC WTG +KE + H C +I CP+ C LE+H + +CP+R + C++C+ + H ++C K+P+ C GC KK+I RE +H++ C K C F GCD K + R+ L F V+ L+ C+ ++ EN R +E + + Y Q ++ ++ LE+ G + +WKI ++ +K +A G+ +FS F TS++GYKM L + L GDG RG H SLF + +G D+LL WPF+ ++T L+DQ R++++ +P+ + RP +D N + G F L L++ + YIRDD IFIKA VD
Sbjct: 4 QEPSPPSSLEGNKPGFPRKILANKLEDKHLCNICQKILRRPFQ-AQCGH-----------RFSP-----------ASAFPDNAAKREVEALEAVC--INEGCSWTGTIKEYEATHEGQCDFMIIPCPS-CKELLRANELERHNERECPERTLNCKYCKEPFHFKNIKAHDEICPKYPMIC-EGCAKKKIPREKYVDHIKL-CTKFRTPCRFHVVGCDMSVSKPQWNLILTPRDLLYTSFTVPLSQTKVAELSRRCQELELKVGTFENIVCVLNREMERSATTMEAYNRQHRLDQDKIEILNNKVRQLERTVGLRDLSIVEMEGKMREMSAATYDGVFVWKISDFSKKRQDAVAGRAPAMFSPAFYTSKYGYKMCLRIYLNGDGTGRGTHLSLFFVVMRGHSDALLKWPFNQKVTLMLLDQ----NNREHIIDAFRPDISSSS---FQRPVSDMNIASGCPLFCPLSKLDSKNSYIRDDTIFIKAIVD 455
BLAST of TNF receptor-associated factor 4 vs. Ensembl Cavefish
Match: traf6 (TNF receptor associated factor 6 [Source:NCBI gene;Acc:103021325]) HSP 1 Score: 150.599 bits (379), Expect = 7.599e-39 Identity = 128/473 (27.06%), Postives = 211/473 (44.61%), Query Frame = 1
Query: 457 KNPPIITNSN----NQNDVDVIFIDPLEKKYACVVCDQVLRYPVQFDECGHHCCSSCLPELMR-VAPRCPIDQCHIERDKVYVDKEFQKEIDNLGVRCSFYQKGCIWTGVLKELSNHLESCLHRMITCPNNCNVEFEIRFLEKHKQDDCPKRIIQCQFCEASLI-AEVE-ANHLKV-CNKFPIPCPN---GCKKKEILRENLAEHLES------------------------------KCVKQEQDCPFSEYGCDFKGKKKRVREHLNDDFVSHLTLMCEAIKENTRIVEEQSKIITQYQTEVGTFEKRIESLE-KLYGPQLIWKIDNYQEKFNEAKTGKKTTIFSAPFMTSRFGYKMALSVCLYGDGKAR-GKHFSLFICICKGDYDSLLLWPFSHRITFTLIDQCQDPEARKNV-VYTVKPNTCKENAPFLGRPTTDRNA-SFGAQKFVELDVLNTLDYIRDDAIFIKAQV 1740
+NP ++ S +Q DV F PLE KY C +C LR VQ CGH C+ C+ + +R +CP+D + D+++ D ++EI +L VRC GC+ L+ L NH+ C + CP C LE+H +C R+I C C ++I AE + A+H C K P+ C GC++K +LR +LA H++ E C + +++RE + + S L ++E + E QS +T+ + ++ + E+ + L+ + Y +W+++ + + G + S PF T R GYK+ L + L R + SLF+ +G++DS L WP I ++DQ E + +V V KP+ RPT RN FG F++L L+ ++RDD + ++ +V
Sbjct: 38 ENPSTLSVSPSLQPDQQGYDVDFDPPLESKYECPICLMGLRSAVQ-TPCGHRFCNCCIRKSIRDTGQKCPVDNEVLTEDQLFPDNFAKREILSLTVRCR--NVGCMEKMELRHLENHIPHCKFATVPCPQ-CQESVWKSELEEHINQECSHRLITCPDCAENIIYAEKQLASHCDTDCLKAPVACTFSIFGCREK-MLRNDLALHMQEFTQMHMRYMADVLRNQTINGLISSHSASAASPTDSRGASSRPEGACQCNQELQQMRETVLE-LESRLVRQDHKLRELSIRNETQSTQMTELRKKLASLEESMRELQAQQYQGVYVWRLEGFSTHIRNQEAGHPVVLHSPPFYTGRPGYKLCLRLHLQTPNAPRCSNYISLFVHTMQGEFDSQLSWPLQGTIRLAVLDQA---EGQHHVEVMETKPDL-----QAFQRPTVQRNPKGFGYVTFMQLQALHQRGFVRDDVLMVRCEV 496
BLAST of TNF receptor-associated factor 4 vs. Ensembl Cavefish
Match: traf6 (TNF receptor associated factor 6 [Source:NCBI gene;Acc:103021325]) HSP 1 Score: 144.05 bits (362), Expect = 2.010e-36 Identity = 127/497 (25.55%), Postives = 209/497 (42.05%), Query Frame = 1
Query: 457 KNPPIITNSN----NQNDVDVIFIDPLEKKYACVVCDQVLRYPVQFDECGHHCCSSCLPELMR-VAPRCPIDQCHIERDKVYVDKEFQKEIDNLGVRCSFYQKGCIWTGVLKELSNHLESCLHRMITCPNNCNVEFEIRFLEKHKQDDCPKRIIQC--------------------------QFCEASLIAEVEANHLKV-CNKFPIPCPN---GCKKKEILRENLAEHLES------------------------------KCVKQEQDCPFSEYGCDFKGKKKRVREHLNDDFVSHLTLMCEAIKENTRIVEEQSKIITQYQTEVGTFEKRIESLE-KLYGPQLIWKIDNYQEKFNEAKTGKKTTIFSAPFMTSRFGYKMALSVCLYGDGKAR-GKHFSLFICICKGDYDSLLLWPFSHRITFTLIDQCQDPEARKNV-VYTVKPNTCKENAPFLGRPTTDRNA-SFGAQKFVELDVLNTLDYIRDDAIFIKAQV 1740
+NP ++ S +Q DV F PLE KY C +C LR VQ CGH C+ C+ + +R +CP+D + D+++ D ++EI +L VRC GC+ L+ L NH+ C + CP C LE+H +C R+I C ++C LI A+H C K P+ C GC++K +LR +LA H++ E C + +++RE + + S L ++E + E QS +T+ + ++ + E+ + L+ + Y +W+++ + + G + S PF T R GYK+ L + L R + SLF+ +G++DS L WP I ++DQ E + +V V KP+ RPT RN FG F++L L+ ++RDD + ++ +V
Sbjct: 38 ENPSTLSVSPSLQPDQQGYDVDFDPPLESKYECPICLMGLRSAVQ-TPCGHRFCNCCIRKSIRDTGQKCPVDNEVLTEDQLFPDNFAKREILSLTVRCR--NVGCMEKMELRHLENHIPHCKFATVPCPQ-CQESVWKSELEEHINQECSHRLITCPDCAENIIYAEKQFHEQLCLFANTVCEYCNMELIRNQLASHCDTDCLKAPVACTFSIFGCREK-MLRNDLALHMQEFTQMHMRYMADVLRNQTINGLISSHSASAASPTDSRGASSRPEGACQCNQELQQMRETVLE-LESRLVRQDHKLRELSIRNETQSTQMTELRKKLASLEESMRELQAQQYQGVYVWRLEGFSTHIRNQEAGHPVVLHSPPFYTGRPGYKLCLRLHLQTPNAPRCSNYISLFVHTMQGEFDSQLSWPLQGTIRLAVLDQA---EGQHHVEVMETKPDL-----QAFQRPTVQRNPKGFGYVTFMQLQALHQRGFVRDDVLMVRCEV 520
BLAST of TNF receptor-associated factor 4 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000074.1 (pep scaffold:Pmarinus_7.0:GL482142:165593:173010:-1 gene:ENSPMAG00000000066.1 transcript:ENSPMAT00000000074.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 145.591 bits (366), Expect = 5.687e-38 Identity = 106/366 (28.96%), Postives = 161/366 (43.99%), Query Frame = 1
Query: 733 CSFYQKGCIWTGVLKELSNHLESCL--HRMITCPNNCNVEFEIRFLEKHKQDDCPKRIIQCQFCEASLIAEVEANHLKVCNKFPIPCPNGCKKKE----ILRENLAEHLESKCVKQEQDCPFSEYGCDFKGKKKRVREHLNDDFVS--HLTLMCEAIKEN----------TRIVEEQSKI------ITQYQTEVGTFEKRIESLEKL-YGPQLIWKIDNYQEKFNEAKTGKKTTIFSAPFMTSRFGYKMALSVCLYGDGKARGKHFSLFICICKGDYDSLLLWPFSHRITFTLIDQCQDPEARKNVVYTVKPNTCKENAPFLGRPTTDRNASFGAQKFVELDVLNTLDYIRDDAIFIKAQVDCDEM 1755
C F Q GC + G L+ L H H + + N+E ++ L Q Q E + A++ ++ K I K E +++ LA E QE S G + +R L+ + L AI+E+ TR+ S + + + T + + R + LE Y +L+WKI +Y + +A +G+ +++S PF TS FGY+M L GDG RG H SLF + +G+YD+LL WPF R+T TL+DQ AR+ + T KP+ + RPT+D N + G FV L + Y++DD IFIK VD E+
Sbjct: 133 CFFSQFGCKYKGTLQGLKEHESGATQQHLSLVTARSANLELKVSML-------------QSQLAERANSADLLGTRVRELEKELISVGQTASKNESVLCVVQRMLAVQTERLLRLQE-----SMQGTTRRADHDALRGDLDGTAATLHELGTRVAAIEESGGSVTHSSTPTRLAALDSALSRHDTQLFAHDTRLAEMDLRFQVLETASYNGKLVWKIRDYARRKQDAVSGRTLSLYSQPFYTSPFGYRMCARAYLNGDGVGRGTHLSLFFVVMRGEYDALLPWPFRQRVTLTLLDQ---GAARRQLSDTFKPDPASSS---FRRPTSDMNIASGCPLFVSHVALESASYLQDDTIFIKVVVDTGEL 474 HSP 2 Score: 89.7373 bits (221), Expect = 3.069e-19 Identity = 53/165 (32.12%), Postives = 86/165 (52.12%), Query Frame = 1
Query: 679 KVYVDKEFQKEIDNLGVRCSFYQKGCIWTGVLKELSNHLESCLHRMITCPNNCNVEFEIRF-LEKHKQDDCPKRIIQCQFCEASL-IAEVEANHLKVCNKFPIPCPNGCKKKEILRENLAEHLESKCVKQEQDCPFSEYGCDFKGKKKRVREHLNDDFVSHLTLM 1167
+V+ D ++EI L V C GC L +L H+ C+H + CP+ E +R L H C R C++C + +AE ++ C ++PIPCPN C+++ I RE L HL C ++ +C FS++GC +KG + ++EH + HL+L+
Sbjct: 1 QVFRDNCCRREILALRVHCRNDTAGCKQIVELGKLQEHMAVCVHEAVNCPHAGCTERLLRGELVNHVALGCHFRTESCRYCNQQVPLAEKRKHYETRCPRYPIPCPNKCEEQSIAREELVSHL-GICPYKQAECFFSQFGCKYKGTLQGLKEHESGATQQHLSLV 164
BLAST of TNF receptor-associated factor 4 vs. Ensembl Sea Lamprey
Match: traf6 (TNF receptor-associated factor 6 [Source:NCBI gene;Acc:554561]) HSP 1 Score: 134.806 bits (338), Expect = 9.479e-34 Identity = 123/522 (23.56%), Postives = 201/522 (38.51%), Query Frame = 1
Query: 511 FIDPLEKKYACVVCDQVLRYPVQFDECGHHCCSSCLPELMRV---APRCPIDQCHIERDKVYVDKEFQKEIDNLGVRCSFYQKGCIWTGVLKELSNHLESCLHRMITCPNNCNVEFEIRFLEKHKQDDCPKRII--------------------------QCQFCEASLIAEVEANHLKV-CNKFPIPC---PNGCKKK-------------------------EILRENLAEHLESKCVKQEQDCPFS-------------------------EYGCDFKGKKKRVREHLNDDFVSHLTLMCEAIKENTRIVEEQSKIITQYQTEVGTFEKRI-ESLEKLYGPQLIWKIDNYQEKF----------NEAKTGKKTTIFSAPFMTSRFGYKMAL-----------------SVCLYGDGKARGKHFSLFICICKGDYDSLLLWPFSHRITFTLIDQCQDPEARKNVVYTVKPNTCKENAPFLGRPTTDRNA-SFGAQKFVELDVLNTLDYIRDDAIFIKAQV 1740
F PLE KY C +C LR PVQ CGH C +C+ MR+ P+CP+D + +++ D ++EI +L VRC K C G L+ L H C + + C C + R L KH++ +C +RI+ C+ C+ LI E HL+V C + +PC P GC+ + +ILR + + + P S CD + R+RE + + L I+E + + Q ++ + V + E R+ ES +L W+++ + + + S+ F T GY++ L SV L G R H +LF+ + +GDYD L WPF RI +++DQC+ ++ V+ + RP+ RN FG F++++ L+ Y+RDD + ++ +V
Sbjct: 55 FEPPLESKYECPICLMALREPVQ-TPCGHRFCRACILHSMRLRDAGPKCPVDNAVLHEGQLFPDNFAKREILSLTVRCP--NKPCGHRGELRALQEHQLRCEYAQVPC-VRCEMPVCRRDLAKHEEQECMRRIVTCLHCCEKMAYKDSKNHEQMCPLVVVNCKHCQQELIREQLGPHLEVDCQQAQVPCTFSPLGCEAQMVRSLLAAHMHEHTQVHMRLLANGLKILRIQVGQGAQPSSAAGSSAPPNSLSWLSSTSGGDVQTAGASRSQGSRDRAACDCAQELDRLRE-ITRTLEERVVLQLHQIRELSAKTDNQQGLLAEATRLVRSLEARVAESESRLCAGIFTWRVERFSRLLPGGLASGFASDGMHPDAPAVMHSSGFYTGVPGYRLCLRLQVLSGREVPAGAASPSVLLAG----RQPHLALFVHLLQGDYDHRLPWPFKGRIRISVVDQCE-----RDSVHVTEMMDADPQLSAFQRPSVHRNPKGFGYMNFMDINTLHHRSYLRDDCLVVRCEV 562
BLAST of TNF receptor-associated factor 4 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002130.1 (pep scaffold:Pmarinus_7.0:GL484662:8457:12718:-1 gene:ENSPMAG00000001936.1 transcript:ENSPMAT00000002130.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 131.339 bits (329), Expect = 1.737e-33 Identity = 66/176 (37.50%), Postives = 98/176 (55.68%), Query Frame = 1
Query: 1219 ITQYQTEVGTFEKRIESLEKL-YGPQLIWKIDNYQEKFNEAKTGKKTTIFSAPFMTSRFGYKMALSVCLYGDGKARGKHFSLFICICKGDYDSLLLWPFSHRITFTLIDQCQDPEARKNVVYTVKPNTCKENAPFLGRPTTDRNASFGAQKFVELDVLNTLDYIRDDAIFIKAQVD 1743
+T + + T E+R++ LE Y +L+WKI +Y + EA +G+ +++S PF TS FGYKM L GDG RG H SLF + +G+YD+LL WPF R+T +L+DQ AR+++ T P+ + RP D N + G FV L Y+ DD +F++ VD
Sbjct: 244 LTMHDGLLDTAERRLQVLETAGYSGKLVWKIRDYARRKQEAASGRTLSLYSQPFYTSPFGYKMCARAYLNGDGVGRGTHLSLFFVVMRGEYDALLEWPFRRRVTLSLLDQ---GAARRHLSDTFTPDPASGS---FRRPDGDMNVASGCPLFVSHVALEGSSYLVDDTVFVRVVVD 413 HSP 2 Score: 73.9442 bits (180), Expect = 2.572e-14 Identity = 49/175 (28.00%), Postives = 78/175 (44.57%), Query Frame = 1
Query: 802 CLHRMITCP-NNCNVEFEIRFLEKHKQDDCPKRIIQCQFCEASLIAEV-EANHLKVCNKFPIPCPNGCKKKEILRENLAEHLESKCVKQEQDCPFSEYGCDFK-GKKKRVREHLNDDFVSHLTLMCEAIKENTRI----------VEEQSKIITQYQTEVGTFEKRIESLEKLYG 1287
C H + C C + L H+ CP R C++C A++ + E +H + C ++P+PCPN C++ I R L++H+ S C + C F GC FK G + VREH SH TL+ I N+ + +E+ + + V E+ + L G
Sbjct: 1 CPHERVLCDFPRCGTSVQRTRLAAHRAS-CPHRAEFCKYCSAAVTCSLLERHHKEECAQYPLPCPNNCEEHGIPRAELSQHM-SACAMSTKLCGFHMLGCTFKQGTSESVREHEESAVRSHFTLV---ISRNSELELQCARLQCSIEDHTNMSEMLTQRVAQLEQDLSHWSTLTG 170
BLAST of TNF receptor-associated factor 4 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008091.1 (pep scaffold:Pmarinus_7.0:GL477915:34322:50582:-1 gene:ENSPMAG00000007312.1 transcript:ENSPMAT00000008091.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 96.2857 bits (238), Expect = 1.229e-21 Identity = 94/403 (23.33%), Postives = 148/403 (36.72%), Query Frame = 1
Query: 532 KYACVVCDQVLRYPVQFDECGHHCCSSCLPELMRVAPRCPIDQCHIERDKVYV------DKEFQKEIDNLGVRCSFYQKGCIWTGVLKELS-NHLESCLHRMITCPNNCNVEFEIRF-LEKHKQDDCPKRIIQCQFCEASLIAEVEANHLKVCNKFPIPCPNGCKKKEILRENLAEHLESKCVKQEQDCPFSEYGCDFKGKKKRVREHLNDDFVSHLTLMCEAIKE-----------------NTRIVEEQSKIIT----------------------------------QYQTEVGTFE--------------KRIESLEK-LYGPQLIWKIDNYQEKFNEAKTG--KKTTIFSAPFMTSRFGYKMALSVCLYGDGKARGKHFSLFICICKGDYDSLLLWPF 1512
++AC C +LR VQ CGH C C+ L+ R D VY D ++E+ L VRC +GC W G L E H+E C ++ C R L +H +C R + C C L H C C +K I + H E +C+K CP+S GC ++G + + H + HL ++ +A K+ + R+V ++++ T + Q ++ E +R+ LE Y +WKI + + EA G + I S F T+R+GY++ L +C G+ H S + + G YD+ L WP+
Sbjct: 2 RFACGSCQGLLRDAVQ-THCGHRFCKPCIARLITSVHRSCNDTLMNSNFLVYSPTQFFPDAALRREMGVLPVRC--VSEGCEWRGRLLEYDVAHVERCDWVLVPCLLAGCALLLPRAELHRHVAQECSVRPVPCAACAQLLPYRQLQKHQLHCRSRRTRECKLCGQKSIPEDKWQHHEERRCMKNRDTCPYSPLGCLYRGHGESLHNHDKNSVEVHLAIVYDAFKKTFEQLIKGHADNIKHPPSARLVAAEAQLATMDRRVEEVAKRVERDVRVSEASTRQGNIDRDETARLQNKMARVEHSDQETERSILGLTRRLAELENTAYNGMFLWKIKHVINRLREAGNGAERPPQIDSPAFFTTRYGYRLRLRLCRSGE------HVSAYAMLGPGPYDATLAWPY 395
BLAST of TNF receptor-associated factor 4 vs. Ensembl Nematostella
Match: EDO32851 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7STV5]) HSP 1 Score: 347.051 bits (889), Expect = 9.339e-114 Identity = 164/424 (38.68%), Postives = 257/424 (60.61%), Query Frame = 1
Query: 508 IFIDPLEKKYACVVCDQVLRYPVQFDECGHHCCSSCLPELMRVAPRCPIDQCHIERDKVYVDKEFQKEIDNLGVRCSFYQKGCIWTGVLKELSNHLESCLHRMITCPNNCNVEFEIRFLEKHKQDDCPKRIIQCQFCEASLIAEVEANHLKVCNKFPIPCPNGCKKK-EILRENLAEHLESKCVKQEQDCPFSEYGCDFK-------GKKKRVREHLNDDFVSHLTLMCEAIKENTRIVEEQSKIITQYQTEVGTFEKRIESLEKLYGPQLIWKIDNYQEKFNEAKTGKKTTIFSAPFMTSRFGYKMALSVCLYGDGKARGKHFSLFICICKGDYDSLLLWPFSHRITFTLIDQCQDPEARKNVVYTVKPNTCKENAPFLGRPTTDRNASFGAQKFVELDVLNTLDYIRDDAIFIKAQVDCDEM 1755
+F+ PL+KKY C+ C+ +L YPVQ CGH C+ C +L+ + RCP + + +DK F +EI L V+C + C W G + E S+H+E C + I C N+C +F+ RFL KH DCP+++I C +C+ + + + HL+ C P PCPN C KK I R L H+E+ C + + C + GC + G ++++ +H + ++H+ ++ + +N ++ S+ ++++ T + EKR+ LEK+ QLIW+I++Y K EAK G T+FS F TS+ GY++ SVCL GDGK +G H S+FI + KG +D+LL WPF +R+TF L+DQ DP RK++ +++KPN C +N PFLGRP ++NASFG KF + + + + +YI++D IF+K VDCD +
Sbjct: 34 LFVYPLQKKYICLDCEGLLWYPVQIKPCGHRVCTKCYTKLLSSSARCPGCMDELNENIPDIDKAFHEEIQELDVKCRNVEWNCKWEGCVNEFSSHVEKCDYSDILCENDCGAKFQRRFLTKHLDKDCPEKLITCLYCDEKHLRKDKKGHLENCPLLPCPCPNKCDKKLTIHRCELDSHVENDCPRTKLMCEYEVLGCGHRITGLEGGGSREKMPKHNKTNIIAHVKMVADLALKNKELIMRFSEKLSEHGTLIEKHEKRLNDLEKIAHSQLIWRIEDYTRKMKEAKAGNTDTLFSPTFTTSKHGYRLCASVCLNGDGKGKGTHMSVFISVLKGAFDALLKWPFDYRVTFVLLDQNDDPAQRKHIRFSIKPNPCADNEPFLGRPRLEKNASFGGAKFAKHEEIVSRNYIKEDTIFLKISVDCDGL 457
BLAST of TNF receptor-associated factor 4 vs. Ensembl Nematostella
Match: EDO32849 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7STV3]) HSP 1 Score: 317.39 bits (812), Expect = 3.404e-102 Identity = 149/412 (36.17%), Postives = 244/412 (59.22%), Query Frame = 1
Query: 526 EKKYACVVCDQVLRYPVQFDECGHHCCSSCLPELMRVA-PRCPIDQCHIERDKVYVDKEFQKEIDNLGVRCSFYQKGCIWTGVLKELSNHLESCLHRMITCPNNCNVEFEIRFLEKHKQDDCPKRIIQCQFCEASLIAEVEANHLKVCNKFPIPCPNGCKKK-EILRENLAEHLESKCVKQEQDCPFSEYGCDFKGKKKRVREHLNDDFVSHLTLMCEAIKENTRIVEEQSKIITQYQTEVGTFEKRIESLEKLYGPQLIWKIDNYQEKFNEAKTGKKTTIFSAPFMTSRFGYKMALSVCLYGDGKARGKHFSLFICICKGDYDSLLLWPFSHRITFTLIDQCQDPEARKNVVYTVKPNTCKENAPFLGRPTTDRNASFGAQKFVELDVLNTLDYIRDDAIFIKAQVDCDEM 1755
E+K+ C VC+ + PVQ ECGH C C + R P+CP ++ VD+ F+ +++ L RC ++ GC ++ H C + I C N+C +F+ RF +KH DCPK+II C +C+ + E + HL+ C P+PCPN C K I R L EH+E +C + + C F GC + ++++ +H+ + + H+ ++ + E ++ ++ +++T + + R+ LEK+ Q+IW+I++Y K EAK G T+FS F TS+ GY++ SVCL GDGK +G H S+F+ + KG +D+LL WPF +R+TF L++Q ++PE RK+V +++KPN +N PFLGRP ++NASFG KF++ + + + ++I+DD +F+K VDCD +
Sbjct: 50 ERKHLCPVCEDIFVSPVQIKECGHRLCQHCYKTIWRSPEPKCPKCSGDLDDKIPDVDQAFENDMNELPCRCINHEWGCKVEVPFTQMITHKGECEYSDILCDNDCGAKFQRRFKQKHLDKDCPKKIISCPYCDDRHLRENKKEHLEDCLLIPLPCPNKCDKTLTIPRGQLDEHIEKECPRAKLMCEFESLGCQHRCSREKMAKHMKSEIIGHVKMIFGVVLEQKEKLDNHAQKFEEHETIMKQVDSRVGDLEKIAHSQIIWRIEDYTRKLKEAKAGNAETLFSPTFTTSKHGYRLCASVCLNGDGKGKGTHMSVFVSVLKGAFDALLKWPFHYRVTFFLLNQHENPEERKHVKFSIKPNPIPDNEPFLGRPRLEKNASFGGAKFIKHEEIESGNFIKDDTVFLKVSVDCDGL 461
BLAST of TNF receptor-associated factor 4 vs. Ensembl Nematostella
Match: EDO49545 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RGK7]) HSP 1 Score: 266.929 bits (681), Expect = 1.652e-83 Identity = 151/417 (36.21%), Postives = 221/417 (53.00%), Query Frame = 1
Query: 511 FIDPLEKKYACVVCDQVLRYPVQFDECGHHCCSSCLPELMRVAPR---CPIDQCHIERDKVYVDKEFQKEIDNLGVRCSFYQKGCIWTGVLKELSNHLESCLHRMITCPN-NCNVEFEIRFLEKHKQDDCPKRIIQCQFCEASLIAEVEANHLKVCNKFPIPCPNGCKKKEILRENLAEHLESKCVKQEQDCPFSEYGCDFKGKKKRVREHLNDDFVSHLTLMCEAIKENTRIVEEQSKIITQYQTEVGTFEKRIESLEKLYGPQLIWKIDNYQEKFNEA-KTGKKTTIFSAPFMTSRFGYKMALSVCLYGDGKARGKHFSLFICICKGDYDSLLLWPFSHRITFTLIDQCQDPEARKNVVYTVKPNTCKENAPFL-GRPTTDRNASFGAQKFVELDVLNTLDYIRDDAIFIKAQVD 1743
F++PL ++Y C +C R P+Q +ECGH C SCL EL R+ CP+D+ I KV+VDK ++ I LGV+C +++ C WTG L + H ++C H + C N CN R L+ H C RI+ C FC + H+K C + PI C N C K+I RE + H+ S+C C + + GC FKG++ + EH + +HL + C+ I+EN E + T G F +WKI NY+ ++++A + ++ IFS PF TS++GYK+ L L G + +G H SL+I I KGDYD+LL WPF +ITF LIDQ E + + + + PN N + RPT N G FV +VL + +Y++DD +FIKA V+
Sbjct: 16 FVEPLPEEYECPICQLAFRDPIQIEECGHRFCQSCLQELRRLQGSPVLCPMDRRPISSTKVFVDKAARRAILGLGVKCWNWKRKCEWTGELSNIEEHAKNCAHEDVHCTNPECNEVMPRRSLQYHLVSKCKWRIVSCHFCTEMYTYKDGKTHMKSCKRLPIECVNKCGAKDIPREEMPFHM-SECPLAVHPCMYRDIGCPFKGRRDALEEHCKNAVHTHLNIACQKIREN-----ESRSLCTN-----GIF---------------LWKISNYKHQYDQAVASPEELAIFSPPFYTSQYGYKLRLKAYLNGRDRGKGTHLSLYIIIMKGDYDALLEWPFKQKITFYLIDQ---SEKQNHRTHLLSPNRSLPNIKVVFNRPTVKENLGIGNPCFVPNEVLESGEYVKDDVMFIKAVVE 403
BLAST of TNF receptor-associated factor 4 vs. Ensembl Nematostella
Match: EDO45915 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RRA4]) HSP 1 Score: 256.144 bits (653), Expect = 3.667e-79 Identity = 137/417 (32.85%), Postives = 219/417 (52.52%), Query Frame = 1
Query: 502 DVIFIDPLEKKYACVVCDQVLRYPVQFDECGHHCCSSCLPELMR-VAPRCPIDQCHIERDKVYVDKEFQKEIDNLGVRCSFYQKGCIWTGVLKELSNHLE-SCLHRMITCPNNCNVEFEIRFLEKHKQDDCPKRIIQCQFCEASLIAEVEANHLKVCNKFPIPCPNGCKKKEILRENLAEHLESKCVKQEQDCPFSEYGCDFKGKKKRVREHLNDDFVSHLTLMCEAIKENTRIVEEQSKIITQYQTEVGTFEKRIESLEKLYGPQLIWKIDNYQEKFNEAKTGKKT-TIFSAPFMTSRFGYKMALSVCLYGDGKARGKHFSLFICICKGDYDSLLLWPFSHRITFTLIDQCQDPEARKNVVYTVKPNTCKENAPFLGRPTTDRNASFGAQKFVELDVLNTLDYIRDDAIFIKAQVD 1743
+V F+ PL+K + C VC LR PVQ CGH C +C+ ++R PRCP+D + K++ D ++I ++ + C + GC W G + +L HLE C + CP +C E LE H +C +R++ C C ++ HL+ C FPI CP C K++ +E LA HL +C C F+E GC FK K++++ H+ + SH+ ++C+ + E + Q + + + + + +E + + IWKI + K +AKTG+ + + S F TS GYKM V L G G RG++ S+ + + G++DS+L WP R TFTL+DQ +D + +++VV T +P + + RP+ DR GA++FV D + Y +D+ IFIK V
Sbjct: 5 EVRFVVPLDKSFECPVCLMALRDPVQVTPCGHRVCQTCIKPIIRNRRPRCPLDNLTLNVGKIFPDNACHRQILSMDILCPHHGDGCEWQGTISDLEKHLERGCNLSEVRCPKDCGASVERGKLEGH-YPECSRRLVNCTHCNKEVVFADMNVHLQSCASFPISCPLTCGAKDLTKEALAVHLNQECPLLVIPCRFAEAGCTFKAKRQKMAAHVQESLTSHVAMLCDLVCEQKLQISAQKERLLLQKEHIQL--QIVECRSRCANGEFIWKIQCFSRKLMDAKTGRASEPMISEAFYTSPHGYKMCAGVWLNGIGTGRGRYISVGLQVQSGEFDSILKWPLYPRYTFTLLDQSEDTKTKRDVVATFEPQS-------ISRPSADRQLGKGARRFVLQDEVCGTTYCKDNTIFIKFSVS 411
BLAST of TNF receptor-associated factor 4 vs. Ensembl Nematostella
Match: EDO40665 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S6K0]) HSP 1 Score: 221.09 bits (562), Expect = 2.777e-66 Identity = 141/454 (31.06%), Postives = 218/454 (48.02%), Query Frame = 1
Query: 409 LSSVS-IDSVGIFHNQIKNPPIITNSNNQNDVDVIFIDPLEKKYACVVCDQVLRYPVQFDECGHHCCSSCLPELMRVAPR-CPIDQCHIERDKVYVDKEFQKEIDNLGVRCSFYQKGCIWTGVLKELSNHLESCLHRMITCPNNCNVEFEIRFLEKHKQDDCPKRIIQCQFCEASLIAEVEANHLKVCNKFPIPCPNGCKKKEILRENLAEHLE--SKCVKQEQDCPFSEYGCDFKGKKKRVREHLNDDFVSHLTLMCEAIKENTRIVEEQSKIITQYQTEVGTFEKRIESLEKLYGPQLIWKIDNYQEKFNEAKTGK-KTTIFSAPFMTSRFGYKMALSVCLYGDGKARGKHFSLFICICKGDYDSLLLWPFSHRITFTLIDQCQDPEARKNVVYTVKPNTCKENAPFLGRPTTDRNASFGAQKFVELDVLNTLDYIRDDAIFIKAQVDCDEM 1755
++SVS ++ +F++ P + N + F+ + Y C +C R PVQ +CGH C SCL ++R P CPID+ I RDKVY DK ++ + +L V+C + C W G L L P+N + +E+ + +V H++ C + PI C N C + +I RE +A H++ C C +S+ GC K K+ + +HL D SHL + I+E + + Q KI T G F +WKI NY + F ++ T K K + S PF T ++GYK+ L G G+ +G H SL++ I KGDYDS+L WPF R+ F LIDQ D +R+N + + TC N+ + GRP ++ FG KFV + L + +++RD+ +FI +V+ +M
Sbjct: 1 MASVSGLNQTALFNSN----PTVLNKKEAGGFEADFVCTIPPDYQCPICQLPFRDPVQTRDCGHRFCESCLEPILRKPPAFCPIDRRCISRDKVYPDKACKRTVLSLTVKCPNHVTDCEWVGELGNL--------------PSNSSNSYEV-------------------------LVKV---HIEACKRVPIKCVNNCGRTDIAREEMAVHIDVDGDCPLATVPCKYSDVGCKTKVKRIEMEKHLQDSMASHLDMAHIRIRE---LEQRQEKICTN-----GKF---------------LWKISNYTQLFQQSATKKEKEKLCSPPFYTGQYGYKLRAEAFLNGLGQGKGTHLSLYVVIMKGDYDSVLPWPFQQRVDFILIDQDDDFTSRQNKTWRL---TCDRNSDYFGRPNKAKSLGFGCPKFVSQETLKSRNFVRDNTVFIMIEVEPLDM 382
BLAST of TNF receptor-associated factor 4 vs. Ensembl Medaka
Match: traf4a (TNF receptor associated factor 4 [Source:NCBI gene;Acc:101161428]) HSP 1 Score: 251.521 bits (641), Expect = 2.237e-76 Identity = 144/482 (29.88%), Postives = 229/482 (47.51%), Query Frame = 1
Query: 502 DVIFIDPLEKKYACVVCDQVLRYPVQFDECGHHCCSSCLPELMRVAP-RCPIDQCHIERDKVYVDKEFQKEIDNLGVRCSFYQKGCIWTGVL---------------------------KELSNHLES---------------------------CLHRMITCPNNCNVEFEIRFLEKHKQDDCPKRIIQCQFCEASLIAEVEANHLKVCNKFPIPCPNGCKKKEILRENLAEHLESKCVKQEQDCPFSEYGCDFKGKKKRVREHLNDDFVSHLTLMCEAIKENTRIVEEQSKIITQYQTEVGTFEKRIESLEKLYGPQLIWKIDNYQEKFNEAKTGKKTTIFSAPFMTSRFGYKMALSVCLYGDGKARGKHFSLFICICKGDYDSLLLWPFSHRITFTLIDQCQDPEARK--NVVYTVKPNTCKENAPFLGRPTTDRNA------SFGAQKFVELDVLNTLDYIRDDAIFIKAQVDCDEMI 1758
D F++ ++++ C +C + +R PVQ CGH C +CL E + +CP DQ ++ K+Y D E +++I +L +RC ++GC WTG + ++L +HL+ C + C N C R L +H +CPKR C++C + + NH C +FP+ CPN C I RE+LA H++ C CPF + GC + K + HL D SHLT+MC ++++ + E+ + +E L + LIWK+++Y K EAK FS PF T R+GYK+ +S L G+G G H S++I + G+YD+LL WPFS+++TF+++DQ DP K ++ T P+ +N +P + RN+ FG KF+ + + +YIRD+ IFIKA ++ + I
Sbjct: 5 DYKFLEKPKRRFQCPLCSKAMREPVQVSTCGHRFCDTCLQEFLSEGVFKCPEDQLPLDYAKIYPDPELEQQILSLPIRCIHSEEGCRWTGQMKQLQGHFSTCAFNVIPCPNRCSVKLTRRDLPDHLQHDCPKRKVKCEFCGSEFTGEAFENHQGVCPQESVYCENKCGARMMRRLLSQHGMAECPKRTQPCKYCGKEFVFDTIQNHQFHCPRFPVQCPNQCGTPNIAREDLANHVKDNCGSALVLCPFKDAGCKHRCPKLAIGRHLEDTTKSHLTMMC--------------NLVSRQRQEILELRREMEELSVSHDGVLIWKLNDYSRKLQEAKLRSNHEFFSPPFYTHRYGYKLQVSAFLNGNGSGEGSHLSVYIRVLPGEYDNLLEWPFSYKVTFSILDQ-SDPSLSKPQHITETFNPDPNWKN---FQKPCSTRNSLDESTLGFGYPKFISHEEIKKRNYIRDNCIFIKASIEIPQKI 468
BLAST of TNF receptor-associated factor 4 vs. Ensembl Medaka
Match: traf4a (TNF receptor associated factor 4 [Source:NCBI gene;Acc:101161428]) HSP 1 Score: 251.906 bits (642), Expect = 3.526e-76 Identity = 144/484 (29.75%), Postives = 230/484 (47.52%), Query Frame = 1
Query: 502 DVIFIDPLEKKYACVVCDQVLRYPVQFDECGHHCCSSCLPELMRVAP-RCPIDQCHIERDKVYVDKEFQKEIDNLGVRCSFYQKGCIWTGVL---------------------------KELSNHLES---------------------------CLHRMITCPNNCNVEFEIRFLEKHKQDDCPKRIIQCQFCEASLIAEVEANHLKVCNKFPIPCPNGCKKKEILRENLAEHLESKCVKQEQDCPFSEYGCDFKGKKKRVREHLNDDFVSHLTLMCEAIKENTRIVEEQSKIITQYQTEVGTFEKRIESLEKLYGPQLIWKIDNYQEKFNEAKTGKKTTIFSAPFMTSRFGYKMALSVCLYGDGKARGKHFSLFICICKGDYDSLLLWPFSHRITFTLIDQCQDPEARK--NVVYTVKPNTCKENAPFLGRPTTDRNA------SFGAQKFVELDVLNTLDYIRDDAIFIKAQVDCDEMINI 1764
D F++ ++++ C +C + +R PVQ CGH C +CL E + +CP DQ ++ K+Y D E +++I +L +RC ++GC WTG + ++L +HL+ C + C N C R L +H +CPKR C++C + + NH C +FP+ CPN C I RE+LA H++ C CPF + GC + K + HL D SHLT+MC ++++ + E+ + +E L + LIWK+++Y K EAK FS PF T R+GYK+ +S L G+G G H S++I + G+YD+LL WPFS+++TF+++DQ DP K ++ T P+ +N +P + RN+ FG KF+ + + +YIRD+ IFIKA ++ + I +
Sbjct: 5 DYKFLEKPKRRFQCPLCSKAMREPVQVSTCGHRFCDTCLQEFLSEGVFKCPEDQLPLDYAKIYPDPELEQQILSLPIRCIHSEEGCRWTGQMKQLQGHFSTCAFNVIPCPNRCSVKLTRRDLPDHLQHDCPKRKVKCEFCGSEFTGEAFENHQGVCPQESVYCENKCGARMMRRLLSQHGMAECPKRTQPCKYCGKEFVFDTIQNHQFHCPRFPVQCPNQCGTPNIAREDLANHVKDNCGSALVLCPFKDAGCKHRCPKLAIGRHLEDTTKSHLTMMC--------------NLVSRQRQEILELRREMEELSVSHDGVLIWKLNDYSRKLQEAKLRSNHEFFSPPFYTHRYGYKLQVSAFLNGNGSGEGSHLSVYIRVLPGEYDNLLEWPFSYKVTFSILDQ-SDPSLSKPQHITETFNPDPNWKN---FQKPCSTRNSLDESTLGFGYPKFISHEEIKKRNYIRDNCIFIKASIEIPQKIMV 470
BLAST of TNF receptor-associated factor 4 vs. Ensembl Medaka
Match: traf4a (TNF receptor associated factor 4 [Source:NCBI gene;Acc:101161428]) HSP 1 Score: 239.195 bits (609), Expect = 7.528e-72 Identity = 141/482 (29.25%), Postives = 225/482 (46.68%), Query Frame = 1
Query: 502 DVIFIDPLEKKYACVVCDQVLRYPVQFDECGHHCCSSCLPELMRVA-PRCPIDQCHIERDKVYVDKEFQKEIDNLGVRCSFYQKGCIWTGVL---------------------------KELSNHLES---------------------------CLHRMITCPNNCNVEFEIRFLEKHKQDDCPKRIIQCQFCEASLIAEVEANHLKVCNKFPIPCPNGCKKKEILRENLAEHLESKCVKQEQDCPFSEYGCDFKGKKKRVREHLNDDFVSHLTLMCEAIKENTRIVEEQSKIITQYQTEVGTFEKRIESLEKLYGPQLIWKIDNYQEKFNEAKTGKKTTIFSAPFMTSRFGYKMALSVCLYGDGKARGKHFSLFICICKGDYDSLLLWPFSHRITFTLIDQCQDPEARK--NVVYTVKPNTCKENAPFLGRPTTDRNA------SFGAQKFVELDVLNTLDYIRDDAIFIKAQVDCDEMI 1758
D F++ ++++ C +C + +R PVQ CGH C +CL E + + P + Q +Y D E +++I +L +RC ++GC WTG + ++L +HL+ C + C N C R L +H +CPKR C++C + + NH C +FP+ CPN C I RE+LA H++ C CPF + GC + K + HL D SHLT+MC ++++ + E+ + +E L + LIWK+++Y K EAK FS PF T R+GYK+ +S L G+G G H S++I + G+YD+LL WPFS+++TF+++DQ DP K ++ T P+ +N +P + RN+ FG KF+ + + +YIRD+ IFIKA ++ + I
Sbjct: 5 DYKFLEKPKRRFQCPLCSKAMREPVQVSTCGHRFCDTCLQEFLSIFFPMGLLPQ-------IYPDPELEQQILSLPIRCIHSEEGCRWTGQMKQLQGHFSTCAFNVIPCPNRCSVKLTRRDLPDHLQHDCPKRKVKCEFCGSEFTGEAFENHQGVCPQESVYCENKCGARMMRRLLSQHGMAECPKRTQPCKYCGKEFVFDTIQNHQFHCPRFPVQCPNQCGTPNIAREDLANHVKDNCGSALVLCPFKDAGCKHRCPKLAIGRHLEDTTKSHLTMMC--------------NLVSRQRQEILELRREMEELSVSHDGVLIWKLNDYSRKLQEAKLRSNHEFFSPPFYTHRYGYKLQVSAFLNGNGSGEGSHLSVYIRVLPGEYDNLLEWPFSYKVTFSILDQ-SDPSLSKPQHITETFNPDPNWKN---FQKPCSTRNSLDESTLGFGYPKFISHEEIKKRNYIRDNCIFIKASIEIPQKI 461
BLAST of TNF receptor-associated factor 4 vs. Ensembl Medaka
Match: traf3 (TNF receptor associated factor 3 [Source:NCBI gene;Acc:101161601]) HSP 1 Score: 192.586 bits (488), Expect = 1.630e-54 Identity = 130/434 (29.95%), Postives = 205/434 (47.24%), Query Frame = 1
Query: 511 FIDPLEKKYACVVCDQVLRYPVQFDECGHHCCSSCLPELMRVA-PRCPIDQCHIERDKVYVDKEFQKEIDNLGVRCSFYQKGCIWTGVLKELSNHLESCLHRMITCP-NNCNVEFEIRFLEKHKQDDCPKRIIQCQFCEASL-IAEVEANHLKVCNKFPIPCPNGCKKKEILREN--LAEHLES--------KCVKQEQDCPFSEYGCDFKGKKKRVREHLNDDFVSHLTLMCEAIKENTRI-----VEEQSKIITQYQTEVGTFEKRIESLEKL-YGPQLIWKIDNYQEKFNEAKTGKKTTIFSAPFMTSRFGYKMALSVCLYGDGKARGKHFSLFICICKGDYDSLLLWPFSHRITFTLIDQCQDPEARKNVVYTVKPNTCKENAPFLGRPTTDRNASFGAQKFVELDVLNTLDYIRDDAIFIKAQVDCDEM 1755
F++ E KY C C VL P Q ECGH C SC+ +++ P CP D + +DK++ D +EI L V C GC L+++ +H+ C + CP C + + +H C R C+FC+ + + E++ + VC FP+ CPN C + R ++ H E + ++Q +D S +G VR L+ A+++ R + +++ ++ + + R + LE Y LIWKI +Y+ + +A GK +++S PF T FGYKM V L GDG +G H SLF + +G+YD+LL WPF ++T L+DQ +RK++ KP+ + RP + N + G FV VL + YI+DD IFIK VD ++
Sbjct: 38 FVEAPEAKYCCEACRLVLCQPRQ-TECGHRFCYSCINDILSCPNPVCPADMEPLFKDKIFRDVCCHREIMALKVYCRSEANGCQEQMSLQQIPDHVNVCPFFEVPCPLGKCKERMMRKEIPEHLAWKCKYRESTCEFCKNKMPLTELQKHKETVCPAFPVSCPNHCTSSSLPRSEKLMSSHTEKLLELELELRSLRQLRDEMES-----LRGTLDTVRTRLS------------ALEQGGRASLETQLNRHDDMLSVHEIRLADMDLRFQVLETASYNGTLIWKIRDYKRRKQDAVAGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVVMRGEYDALLPWPFKQKVTLMLMDQ---GPSRKHLGDAFKPDPSSSS---FRRPVAEMNIASGCPLFVSQSVLESGTYIKDDTIFIKVTVDTSDL 447
BLAST of TNF receptor-associated factor 4 vs. Ensembl Medaka
Match: traf2b (TNF receptor associated factor 2 [Source:NCBI gene;Acc:101159764]) HSP 1 Score: 156.377 bits (394), Expect = 9.325e-41 Identity = 138/503 (27.44%), Postives = 207/503 (41.15%), Query Frame = 1
Query: 520 PLEKKYACVVCDQVLRYPVQFDECGHHCCSSCLPELMRVAPRCPIDQCHIER-----------DKVYVDKEFQKEIDNLGVRCSFYQKGCIWTGVLKEL-SNHLESCLHRMITCPNNCNVEFEIRFLEKHKQDDCPKRIIQCQFCEASL-IAEVEA--------------------------NHLKVCNKFPIPCP---NGCKK-------KEILRENLAEHLE----------------SKCVKQEQDCPFSEY-----GCDFKG--------KKKRVREH----LNDDFVSHLTLMCEAIKENTRI----VEEQSKIITQYQTEVGTFEKRIESLEKL--------YGPQLIWKIDNYQEKFNEAKTGKKTTIFSAPFMTSRFGYKMALSVCLYGDGKARGKHFSLFICICKGDYDSLLLWPFSHRITFTLIDQCQDPEARKNVVYTVKPNTCKENAPFLGRPTTDRNASFGAQKFVELDVL-NTLDYIRDDAIFIKAQVD 1743
P+E KY C C QVLR PVQ +CGH C C +L P+ P C E + + D +EI +L RC +GC WTG +KE + H C I C C + ++H +C +R + C++C+ + +++A +H K C K CP GCK E + EHL S + ++D Y GC KK E+ LN + V +L EA R+ +E S I Q + + + ++ E++ Y +WKI ++ + EA +G+ +FS F +S++GYKM L + L GDG RG H SLF + + YD+LL WPFS ++T L+DQ R++++ +P+ + RP ++ N + G F L L Y+RDD IFIKA VD
Sbjct: 30 PMEDKYKCQQCLQVLRKPVQA-QCGHRFCVHCFRQLTSSGPK-PCQACRKEEIYEEPMSILNSSEAFPDNAAGREIASLPARC--LNQGCDWTGSIKEYEAKHEGRCEFEQIQC-EACQALVLRKDKDRHNDRECEERTLNCKYCKVTFNFKDIKAHDEICQKFPLQCKDCGKKKIPREKFNDHAKSCAKSKSACPFSEVGCKSVVENGKISEHEHSSTMEHLRLLLPMVLSMTRTRLDTSPSGEWQEDSGLGLYRAPDDGCGAAASVPSVDLDKKVSALENIVCVLNRE-VERSSLTLEAFSHQHRLDQEKIENLSNKIRQLERSLTVKDLQLSEAEQMVRELQYCTYDGIFVWKITDFSHRRQEAVSGRAPAMFSPAFYSSKYGYKMCLRLYLNGDGTGRGTHLSLFFVVMRSKYDALLKWPFSQKVTLMLLDQ----NNREHIIDAFRPDI---TSTSFQRPVSEMNIASGCPLFCPLAKLAGKSPYLRDDTIFIKAIVD 519
BLAST of TNF receptor-associated factor 4 vs. Planmine SMEST
Match: SMESG000016362.1 (SMESG000016362.1) HSP 1 Score: 786.178 bits (2029), Expect = 0.000e+0 Identity = 379/379 (100.00%), Postives = 379/379 (100.00%), Query Frame = 1
Query: 628 MRVAPRCPIDQCHIERDKVYVDKEFQKEIDNLGVRCSFYQKGCIWTGVLKELSNHLESCLHRMITCPNNCNVEFEIRFLEKHKQDDCPKRIIQCQFCEASLIAEVEANHLKVCNKFPIPCPNGCKKKEILRENLAEHLESKCVKQEQDCPFSEYGCDFKGKKKRVREHLNDDFVSHLTLMCEAIKENTRIVEEQSKIITQYQTEVGTFEKRIESLEKLYGPQLIWKIDNYQEKFNEAKTGKKTTIFSAPFMTSRFGYKMALSVCLYGDGKARGKHFSLFICICKGDYDSLLLWPFSHRITFTLIDQCQDPEARKNVVYTVKPNTCKENAPFLGRPTTDRNASFGAQKFVELDVLNTLDYIRDDAIFIKAQVDCDEMINI 1764
MRVAPRCPIDQCHIERDKVYVDKEFQKEIDNLGVRCSFYQKGCIWTGVLKELSNHLESCLHRMITCPNNCNVEFEIRFLEKHKQDDCPKRIIQCQFCEASLIAEVEANHLKVCNKFPIPCPNGCKKKEILRENLAEHLESKCVKQEQDCPFSEYGCDFKGKKKRVREHLNDDFVSHLTLMCEAIKENTRIVEEQSKIITQYQTEVGTFEKRIESLEKLYGPQLIWKIDNYQEKFNEAKTGKKTTIFSAPFMTSRFGYKMALSVCLYGDGKARGKHFSLFICICKGDYDSLLLWPFSHRITFTLIDQCQDPEARKNVVYTVKPNTCKENAPFLGRPTTDRNASFGAQKFVELDVLNTLDYIRDDAIFIKAQVDCDEMINI
Sbjct: 1 MRVAPRCPIDQCHIERDKVYVDKEFQKEIDNLGVRCSFYQKGCIWTGVLKELSNHLESCLHRMITCPNNCNVEFEIRFLEKHKQDDCPKRIIQCQFCEASLIAEVEANHLKVCNKFPIPCPNGCKKKEILRENLAEHLESKCVKQEQDCPFSEYGCDFKGKKKRVREHLNDDFVSHLTLMCEAIKENTRIVEEQSKIITQYQTEVGTFEKRIESLEKLYGPQLIWKIDNYQEKFNEAKTGKKTTIFSAPFMTSRFGYKMALSVCLYGDGKARGKHFSLFICICKGDYDSLLLWPFSHRITFTLIDQCQDPEARKNVVYTVKPNTCKENAPFLGRPTTDRNASFGAQKFVELDVLNTLDYIRDDAIFIKAQVDCDEMINI 379
BLAST of TNF receptor-associated factor 4 vs. Planmine SMEST
Match: SMESG000006747.1 (SMESG000006747.1) HSP 1 Score: 227.254 bits (578), Expect = 8.094e-67 Identity = 133/436 (30.50%), Postives = 229/436 (52.52%), Query Frame = 1
Query: 490 QNDVDVIFIDPLEKKYACVVCDQVLRYPVQFDECGHHCCSSCLP---ELMRVAPRCPIDQCHIERDKVYVDKEFQKEIDNLGVRCSFYQKGCIWTGVLKELSNHLESCLHRMITCPNNCNVEFEIRFLEKHKQDDCPKRIIQCQFCEASLIAEVEANHLKVCNKFPIPCPNGCK------KKEILRENLAE-HLESKCVKQEQDCPFSEYGCDFKGKKKRVREHLNDDFVSHLTLMCEAIKENTRIVEEQSKIITQYQTEVGTFEKRIESLEKLYGPQLIWKIDNYQEKFNEAKTGKKTTIFSAPFM-TSRFGYKMALSVCL-YGDGKARGKHFSLFICICKGDYDSLLLWPFSHRITFTLIDQCQDPEARKNVVYTVKPNTCKENAPFLGRPTTDRNASFGAQKFVELDVL-NTLDYIRDDAIFIKAQVDCDEMI 1758
Q + + F + ++ +Y C C ++L P++ +CGH C +C P CPID+ + D++ + ++ I NL + CS C W G+L +H E+C + I CP C+ + E HK + C R + CQFC + ++ +H VC++ I CPN CK K IL++ + + HLE+ C +++ CPF +GC K K+K++ HL + HL ++C ++NT +E+Q + + + + ++ + +I+ L +G QL+WKIDN EK+ A G I S PF T+ +GYK + + + K ++ S+FI IC ++ LL WPF ++ L++Q + K++ + PNT EN PF+ RP T RN FG +KF ++ + ++ +A+FIK ++ E++
Sbjct: 98 QTNNQLSFREEVKLEYFCEKCSRILWNPIKL-KCGHIICYTCQPFPDSFQNDVMNCPIDEETTKEDEIEQCENYKDNIWNLQIYCSTIL--CDWFGILSNFRSHFETCELKQIKCPQ-CDEMIQWGNFEAHKLNTCEMRSVLCQFCSNPIFSKDAKSHENVCDEKLIECPNSCKFPTDKTKAMILKQGILKFHLENACSERKVPCPFEMFGCKNKSKQKKMHHHLTKYAIIHLEMICSFGRKNTESLEKQVRFMLELKDKLERSDGKIKILNSEFGTQLLWKIDNINEKYQAALVGANEEIVSNPFYSTAPYGYKFIMRLVFNVHNVKLSSQYLSIFISICDSPFNVLLPWPFKLKLNIHLVNQI----SEKHISHCFLPNTIVENYPFINRPKTQRNPYFGIEKFANCNIFHDNSPFVAGNAMFIKILIEPHEIV 525
BLAST of TNF receptor-associated factor 4 vs. Planmine SMEST
Match: SMESG000003970.1 (SMESG000003970.1) HSP 1 Score: 213.386 bits (542), Expect = 3.418e-65 Identity = 95/219 (43.38%), Postives = 141/219 (64.38%), Query Frame = 1
Query: 1087 YGCDFKGKKKRVREHLNDDFVSHLTLMCEAIKENTRIVEEQSKIITQYQTEVGTFEKRIESLEKLYGPQLIWKIDNYQEKFNEAKTGKKTTIFSAPFMTSRFGYKMALSVCLYGDGKARGKHFSLFICICKGDYDSLLLWPFSHRITFTLIDQCQDPEARKNVVYTVKPNTCKENAPFLGRPTTDRNASFGAQKFVELDVLNTLD-YIRDDAIFIKAQV 1740
+GC +G + + HL + HL LM EA+ +N+ +E + + + + E R+ E+L+G QLIWK++ + +KF++AK+G TT FS PF +S +GYK+AL +C +GDG A+GK SLF+CIC+G+YD+LL WPF ++TF+L+DQ + RK+VVY+ PN K+N PFLGRPT +RN FGA+KF+ L L Y + IF K +
Sbjct: 2 FGCKIQGNENEIENHLKRKAIPHLVLMAEALTKNSLTLENSVQCLLDEKLKCSALESRLTVFERLWGSQLIWKVERFSQKFSDAKSGVTTTFFSPPFFSSHYGYKLALGLCPFGDGIAKGKFLSLFVCICRGEYDNLLQWPFPLKVTFSLLDQAPEFRKRKDVVYSFVPNVIKDNFPFLGRPTGERNPFFGARKFISLSSLMEYGTYTLNQTIFFKVDI 220
BLAST of TNF receptor-associated factor 4 vs. Planmine SMEST
Match: SMESG000027153.1 (SMESG000027153.1) HSP 1 Score: 184.882 bits (468), Expect = 1.322e-51 Identity = 131/452 (28.98%), Postives = 223/452 (49.34%), Query Frame = 1
Query: 523 LEKKYACVVCDQVLRYPVQFDECGHHCCSSCLPELMRVAPR-CPIDQCHIERDKVYVDKEFQ------KEIDNLGVRCSFYQKGCIWTGVLKELSNHLESCLHRMITCPNNCNVEFEIRFLEKHKQDDCPKRIIQCQFC-EASLIAEVEANHLK-----VCNKFPIPCPNGCKKKEILRENLAEHLESKCVKQEQDCPFSEYGCDF-KGKKKRVREHLNDDFVSHLTLMCEAIKENTRIVE------EQSKIITQYQTEVG-----TFEKRIESLEKL-------------------YGPQLIWKIDNYQEKFNEAKTGKKTTIFSAPFMTSRFGYKMALSVCLYGDGKARGKHFSLFICICKGDYDSLLLWPFSHRITFTLIDQCQDPEARKNVVYTVKPNTCKENAPFLGRPTTDRNASFGAQKFVELD-VLNTLDYIRDDAIFIKAQVD 1743
L + CV+C ++L+ Q CG C +C+ + P+ CP Q E +++D++ KEI +L V+C F K C L+ + H+ SC R I+C N C + + + E H ++ C R ++C++C E ++++ HL C K+ CPN C + L EHL+ C K++ +CPF C+ K K+ + +HLN+++VSH + + IK+ ++ E K++T+ ++ + K E++EKL IWK +++ K +A++G+K ++ S PF TS FGYKM L + GDG +G H S+F I KG++D LL WPF ++T +++DQ K+ T KP+ + +P + N + G+ KF+ L ++N Y ++D I++K VD
Sbjct: 22 LSDRLKCVLCQRILKNAKQ-TSCGCKACENCIKSYLANGPKPCPSKQIDCENVMLHMDEDINADNATNKEIASLKVKCPF--KLCSSEMPLRNMVEHINSCEFREISC-NKCQSKLQAKDKESHDKNKCEMRKLKCEYCLEEMSFRDLKSIHLNSDREDFCVKYTAICPNNCDVH--TKVCLKEHLKL-CSKKKLECPFHSLNCNVDKMTKENLMKHLNEEYVSHTSNLISKIKDMENTIKNLTDELENQKVLTKELLDMNKKSSLSVLKTQETIEKLKTKSFPTPIQAVENKSVIFRNATFIWKFTDFESKRIDAESGRKVSVTSDPFYTSEFGYKMCLRIYPAGDGVGKGTHLSVFFAIMKGEFDDLLSWPFKQKVTLSIMDQ---EAGTKHHSDTFKPDA---RSACYQKPVDECNIASGSPKFILLSLIMNNSLYCKNDTIYLKIAVD 460
BLAST of TNF receptor-associated factor 4 vs. Planmine SMEST
Match: SMESG000027123.1 (SMESG000027123.1) HSP 1 Score: 174.096 bits (440), Expect = 7.164e-48 Identity = 133/448 (29.69%), Postives = 214/448 (47.77%), Query Frame = 1
Query: 514 IDPLEKKYACVVCDQVLRYPVQFDECGHHCCSSCLPELMRVAPR-CPIDQC-----HIERDKVYVDKEFQKEIDNLGVRCSFYQKGCIWTGVLKELSNHLESCLHRMITCPNNCNVEFEIRFLEKHKQDDCPKRIIQCQFCEASL----IAEVEANHLK--VCNKFPIPCPNGCKKKEILRENLAEHLESKCVKQEQDCPFSEYGCDFKGKKKRVREHLN---DDFVSHLTLMCEAIKENTRIVEEQSKIITQYQTEVGTFE-------KRIESLEK--------------LYGPQLIWKIDNYQEKFNEAKTGKKTTIFSAPFMTSRFGYKMALSVCLYGDGKARGKHFSLFICICKGDYDSLLLWPFSHRITFTLIDQCQDPEARKNVVYTVKPNTCKENAPFLGRPTTDRNASFGAQKFVELDVL--NTLDYIRDDAIFIKAQVD 1743
I L C++C +L+ Q +CG C +C+ E + P+ CP +C I++D +Y D KEI NL + C F KGC + ++S H++SC +R +TC + C + +KH +C RI +C+FC ++ + E+ N K +C+++ CPN C + + L NL HLE+ C+ ++ D D ++E N + + + L+ + K+ +E Q II + T+ K+I +LE IWKI + + + A+ ++ +I S PF TS FGYK+ L V GDG +G H S+F + KG+YD LL WPF ++T +L+DQ K+ T KP+ +P RP D N + G+ KF + L N++ Y ++D I+IK VD
Sbjct: 18 IPNLSSSLKCIICSSLLKNAKQ-TKCGCKVCENCINEYLSKGPKDCPNKECLNELLSIDKD-IYNDNATNKEILNLKIACPF--KGCAQLETVFKISQHVKSCEYRDVTC-DPCQKRILAKEKQKHIDGECEMRITKCEFCHKTMTIKYLNEMHLNTTKNELCSEYVGHCPNNCGETKEL--NLKLHLET-CLNRKSD--------DQNDTNYHIQEFSNTQLSNLLKQIALLNQTSKDLLTKLENQDVIIREMSTKYIALTEDNIKLTKKINALEAERSNPVKIIAKTNDFRNGSFIWKIKDLKSQIQNAERSERLSITSDPFYTSEFGYKLCLRVYPSGDGLGKGTHLSVFFALMKGEYDDLLPWPFRQKLTLSLLDQ---ENFTKHYSDTFKPD---PKSPCFQRPILDSNIASGSPKFYSISHLSFNSI-YYKNDTIYIKITVD 442 The following BLAST results are available for this feature:
BLAST of TNF receptor-associated factor 4 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of TNF receptor-associated factor 4 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 2
BLAST of TNF receptor-associated factor 4 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of TNF receptor-associated factor 4 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of TNF receptor-associated factor 4 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of TNF receptor-associated factor 4 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of TNF receptor-associated factor 4 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of TNF receptor-associated factor 4 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of TNF receptor-associated factor 4 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of TNF receptor-associated factor 4 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 4
BLAST of TNF receptor-associated factor 4 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of TNF receptor-associated factor 4 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of TNF receptor-associated factor 4 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of TNF receptor-associated factor 4 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30009756 ID=SMED30009756|Name=TNF receptor-associated factor 4|organism=Schmidtea mediterranea sexual|type=transcript|length=1816bpback to top protein sequence of SMED30009756-orf-1 >SMED30009756-orf-1 ID=SMED30009756-orf-1|Name=SMED30009756-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=509bp MSLDGRQNEIGSNPELGEKDYNNSEYNSLKTGSLSSLNNGYNSPIRPPGLback to top Aliases
The feature 'TNF receptor-associated factor 4' has the following synonyms
Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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