NSD-1
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30009651 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 31Note: Hover over icons to view figure legend
Homology
BLAST of NSD-1 vs. Ensembl Human
Match: NSD2 (nuclear receptor binding SET domain protein 2 [Source:HGNC Symbol;Acc:HGNC:12766]) HSP 1 Score: 390.578 bits (1002), Expect = 1.548e-116 Identity = 237/705 (33.62%), Postives = 338/705 (47.94%), Query Frame = 3
Query: 693 CRYCLETKNIVQCNKCLFNNFHVKCLEFLQNSIETKINDLDRCLECSLGIIRCYACYKIVDISNEQGFMRCIIKTCTKWFHTNCLETGPMLEMTKFPKPGQLVCPCHICHKCELVNPS-PKYRCTKLIVCIMCPATFHTGDWCIPAGSVELNTGEIICPRHLVDLNFSMNIMVPPFVARVKSDLQERIYGNTLTKISEPMTITPSTVTKPTNVNWCFKCGEGGELLCCETCPAAYHFKCTDLKEIPQKFYCPDCASFCYRSYGEIVWIKCGTHPWWPGQILHLENVPKNIAAKKHANGQFVVQFFGSRDYMWRDHGNVFLYEKEDECNSKTSKYRYNNIFLEGIKEAAIGYV----------TREEKWQSGSCDHVMNSKIYNKIQVNKCPLELRRKVVPETPHCNCISFDPKSDCSIGSGCFNVASKCECDPQICNLGDKCKNQNFVKRIYPKQYTFWANDRGWGLKADEFIKTKQFVNEYIGEIITMEESEKRILWANENNITDFYFMELDNGRLIDARQFSNLSRFINNSCDPNLVAEKWIVNREHRIGLFALRDIQKGEELTFQYNLQNKSSNRIVCKCFSVNCSGFLGEAPKMAXXXXXXXXXXXXXXXXXXXXXXXCKSFLTDKNSNSQCFRCGEIIDMLSSIVCSVGPCMKTYHSVCLNLNMANYVQSSWICPHHYCDVCARPSHHFSSNTTESYCNK 2774
C+ C + +++ C FH+ CL L E + C EC+ GI C+ C + ++ RC++ C K++H C++ P+ T F G CP H C C NPS P+ K++ C+ CP +H+GD C+ AG + + IIC H F AR + NV+WCF C +GG LLCCE+CPAA+H C +++ ++C DC + + +I+W+K G + WWP ++ H +NVP NI KH G+F V FFGS+DY W VF Y + D + +F ++EA + T+E + + H+ +K Y K+Q+ + E P CNC D ++ C S C N EC PQ+C G+ C+NQ F KR YP+ + +GWGL A I+ +FVNEY+GE+I EE RI A+EN+IT FY + +D R+IDA N SRF+N+SC PN KW VN + R+GLFA+ DI G ELTF YNL + + VC+C + NCSGFLG+ PK + + K K + S +CFRCG D ++C C K YH CL L + W CP H+CDVC +PS F S+C +
Sbjct: 670 CQLCEKPGSLLLCEGPCCGAFHLACL-GLSRRPEGRFT----CSECASGIHSCFVCKE-----SKTDVKRCVVTQCGKFYHEACVKKYPL---TVFESRG-FRCPLHSCVSCHASNPSNPRPSKGKMMRCVRCPVAYHSGDACLAAGCSVIASNSIICTAH--------------FTARKGKRHHAHV-----------------------NVSWCFVCSKGGSLLCCESCPAAFHPDCLNIEMPDGSWFCNDCRAGKKLHFQDIIWVKLGNYRWWPAEVCHPKNVPPNIQKMKHEIGEFPVFFFGSKDYYWTHQARVFPYMEGDRGSRYQGVRGIGRVFKNALQEAEARFREIKLQREARETQESERKPPPYKHIKVNKPYGKVQIYTAD-------ISEIPKCNCKPTD-ENPCGFDSECLNRMLMFECHPQVCPAGEFCQNQCFTKRQYPETKIIKTDGKGWGLVAKRDIRKGEFVNEYVGELIDEEECMARIKHAHENDITHFYMLTIDKDRIIDAGPKGNYSRFMNHSCQPNCETLKWTVNGDTRVGLFAVCDIPAGTELTFNYNLDCLGNEKTVCRCGASNCSGFLGDRPKTSTTLSSEEKGKKTKKKTRRRR----AKGEGKRQSEDECFRCG---DGGQLVLCDRKFCTKAYHLSCLGLGKRPF--GKWECPWHHCDVCGKPSTSFCHLCPNSFCKE 1306
BLAST of NSD-1 vs. Ensembl Human
Match: NSD2 (nuclear receptor binding SET domain protein 2 [Source:HGNC Symbol;Acc:HGNC:12766]) HSP 1 Score: 390.578 bits (1002), Expect = 1.548e-116 Identity = 237/705 (33.62%), Postives = 338/705 (47.94%), Query Frame = 3
Query: 693 CRYCLETKNIVQCNKCLFNNFHVKCLEFLQNSIETKINDLDRCLECSLGIIRCYACYKIVDISNEQGFMRCIIKTCTKWFHTNCLETGPMLEMTKFPKPGQLVCPCHICHKCELVNPS-PKYRCTKLIVCIMCPATFHTGDWCIPAGSVELNTGEIICPRHLVDLNFSMNIMVPPFVARVKSDLQERIYGNTLTKISEPMTITPSTVTKPTNVNWCFKCGEGGELLCCETCPAAYHFKCTDLKEIPQKFYCPDCASFCYRSYGEIVWIKCGTHPWWPGQILHLENVPKNIAAKKHANGQFVVQFFGSRDYMWRDHGNVFLYEKEDECNSKTSKYRYNNIFLEGIKEAAIGYV----------TREEKWQSGSCDHVMNSKIYNKIQVNKCPLELRRKVVPETPHCNCISFDPKSDCSIGSGCFNVASKCECDPQICNLGDKCKNQNFVKRIYPKQYTFWANDRGWGLKADEFIKTKQFVNEYIGEIITMEESEKRILWANENNITDFYFMELDNGRLIDARQFSNLSRFINNSCDPNLVAEKWIVNREHRIGLFALRDIQKGEELTFQYNLQNKSSNRIVCKCFSVNCSGFLGEAPKMAXXXXXXXXXXXXXXXXXXXXXXXCKSFLTDKNSNSQCFRCGEIIDMLSSIVCSVGPCMKTYHSVCLNLNMANYVQSSWICPHHYCDVCARPSHHFSSNTTESYCNK 2774
C+ C + +++ C FH+ CL L E + C EC+ GI C+ C + ++ RC++ C K++H C++ P+ T F G CP H C C NPS P+ K++ C+ CP +H+GD C+ AG + + IIC H F AR + NV+WCF C +GG LLCCE+CPAA+H C +++ ++C DC + + +I+W+K G + WWP ++ H +NVP NI KH G+F V FFGS+DY W VF Y + D + +F ++EA + T+E + + H+ +K Y K+Q+ + E P CNC D ++ C S C N EC PQ+C G+ C+NQ F KR YP+ + +GWGL A I+ +FVNEY+GE+I EE RI A+EN+IT FY + +D R+IDA N SRF+N+SC PN KW VN + R+GLFA+ DI G ELTF YNL + + VC+C + NCSGFLG+ PK + + K K + S +CFRCG D ++C C K YH CL L + W CP H+CDVC +PS F S+C +
Sbjct: 670 CQLCEKPGSLLLCEGPCCGAFHLACL-GLSRRPEGRFT----CSECASGIHSCFVCKE-----SKTDVKRCVVTQCGKFYHEACVKKYPL---TVFESRG-FRCPLHSCVSCHASNPSNPRPSKGKMMRCVRCPVAYHSGDACLAAGCSVIASNSIICTAH--------------FTARKGKRHHAHV-----------------------NVSWCFVCSKGGSLLCCESCPAAFHPDCLNIEMPDGSWFCNDCRAGKKLHFQDIIWVKLGNYRWWPAEVCHPKNVPPNIQKMKHEIGEFPVFFFGSKDYYWTHQARVFPYMEGDRGSRYQGVRGIGRVFKNALQEAEARFREIKLQREARETQESERKPPPYKHIKVNKPYGKVQIYTAD-------ISEIPKCNCKPTD-ENPCGFDSECLNRMLMFECHPQVCPAGEFCQNQCFTKRQYPETKIIKTDGKGWGLVAKRDIRKGEFVNEYVGELIDEEECMARIKHAHENDITHFYMLTIDKDRIIDAGPKGNYSRFMNHSCQPNCETLKWTVNGDTRVGLFAVCDIPAGTELTFNYNLDCLGNEKTVCRCGASNCSGFLGDRPKTSTTLSSEEKGKKTKKKTRRRR----AKGEGKRQSEDECFRCG---DGGQLVLCDRKFCTKAYHLSCLGLGKRPF--GKWECPWHHCDVCGKPSTSFCHLCPNSFCKE 1306
BLAST of NSD-1 vs. Ensembl Human
Match: NSD2 (nuclear receptor binding SET domain protein 2 [Source:HGNC Symbol;Acc:HGNC:12766]) HSP 1 Score: 390.578 bits (1002), Expect = 1.548e-116 Identity = 237/705 (33.62%), Postives = 338/705 (47.94%), Query Frame = 3
Query: 693 CRYCLETKNIVQCNKCLFNNFHVKCLEFLQNSIETKINDLDRCLECSLGIIRCYACYKIVDISNEQGFMRCIIKTCTKWFHTNCLETGPMLEMTKFPKPGQLVCPCHICHKCELVNPS-PKYRCTKLIVCIMCPATFHTGDWCIPAGSVELNTGEIICPRHLVDLNFSMNIMVPPFVARVKSDLQERIYGNTLTKISEPMTITPSTVTKPTNVNWCFKCGEGGELLCCETCPAAYHFKCTDLKEIPQKFYCPDCASFCYRSYGEIVWIKCGTHPWWPGQILHLENVPKNIAAKKHANGQFVVQFFGSRDYMWRDHGNVFLYEKEDECNSKTSKYRYNNIFLEGIKEAAIGYV----------TREEKWQSGSCDHVMNSKIYNKIQVNKCPLELRRKVVPETPHCNCISFDPKSDCSIGSGCFNVASKCECDPQICNLGDKCKNQNFVKRIYPKQYTFWANDRGWGLKADEFIKTKQFVNEYIGEIITMEESEKRILWANENNITDFYFMELDNGRLIDARQFSNLSRFINNSCDPNLVAEKWIVNREHRIGLFALRDIQKGEELTFQYNLQNKSSNRIVCKCFSVNCSGFLGEAPKMAXXXXXXXXXXXXXXXXXXXXXXXCKSFLTDKNSNSQCFRCGEIIDMLSSIVCSVGPCMKTYHSVCLNLNMANYVQSSWICPHHYCDVCARPSHHFSSNTTESYCNK 2774
C+ C + +++ C FH+ CL L E + C EC+ GI C+ C + ++ RC++ C K++H C++ P+ T F G CP H C C NPS P+ K++ C+ CP +H+GD C+ AG + + IIC H F AR + NV+WCF C +GG LLCCE+CPAA+H C +++ ++C DC + + +I+W+K G + WWP ++ H +NVP NI KH G+F V FFGS+DY W VF Y + D + +F ++EA + T+E + + H+ +K Y K+Q+ + E P CNC D ++ C S C N EC PQ+C G+ C+NQ F KR YP+ + +GWGL A I+ +FVNEY+GE+I EE RI A+EN+IT FY + +D R+IDA N SRF+N+SC PN KW VN + R+GLFA+ DI G ELTF YNL + + VC+C + NCSGFLG+ PK + + K K + S +CFRCG D ++C C K YH CL L + W CP H+CDVC +PS F S+C +
Sbjct: 670 CQLCEKPGSLLLCEGPCCGAFHLACL-GLSRRPEGRFT----CSECASGIHSCFVCKE-----SKTDVKRCVVTQCGKFYHEACVKKYPL---TVFESRG-FRCPLHSCVSCHASNPSNPRPSKGKMMRCVRCPVAYHSGDACLAAGCSVIASNSIICTAH--------------FTARKGKRHHAHV-----------------------NVSWCFVCSKGGSLLCCESCPAAFHPDCLNIEMPDGSWFCNDCRAGKKLHFQDIIWVKLGNYRWWPAEVCHPKNVPPNIQKMKHEIGEFPVFFFGSKDYYWTHQARVFPYMEGDRGSRYQGVRGIGRVFKNALQEAEARFREIKLQREARETQESERKPPPYKHIKVNKPYGKVQIYTAD-------ISEIPKCNCKPTD-ENPCGFDSECLNRMLMFECHPQVCPAGEFCQNQCFTKRQYPETKIIKTDGKGWGLVAKRDIRKGEFVNEYVGELIDEEECMARIKHAHENDITHFYMLTIDKDRIIDAGPKGNYSRFMNHSCQPNCETLKWTVNGDTRVGLFAVCDIPAGTELTFNYNLDCLGNEKTVCRCGASNCSGFLGDRPKTSTTLSSEEKGKKTKKKTRRRR----AKGEGKRQSEDECFRCG---DGGQLVLCDRKFCTKAYHLSCLGLGKRPF--GKWECPWHHCDVCGKPSTSFCHLCPNSFCKE 1306
BLAST of NSD-1 vs. Ensembl Human
Match: NSD2 (nuclear receptor binding SET domain protein 2 [Source:HGNC Symbol;Acc:HGNC:12766]) HSP 1 Score: 390.578 bits (1002), Expect = 1.548e-116 Identity = 237/705 (33.62%), Postives = 338/705 (47.94%), Query Frame = 3
Query: 693 CRYCLETKNIVQCNKCLFNNFHVKCLEFLQNSIETKINDLDRCLECSLGIIRCYACYKIVDISNEQGFMRCIIKTCTKWFHTNCLETGPMLEMTKFPKPGQLVCPCHICHKCELVNPS-PKYRCTKLIVCIMCPATFHTGDWCIPAGSVELNTGEIICPRHLVDLNFSMNIMVPPFVARVKSDLQERIYGNTLTKISEPMTITPSTVTKPTNVNWCFKCGEGGELLCCETCPAAYHFKCTDLKEIPQKFYCPDCASFCYRSYGEIVWIKCGTHPWWPGQILHLENVPKNIAAKKHANGQFVVQFFGSRDYMWRDHGNVFLYEKEDECNSKTSKYRYNNIFLEGIKEAAIGYV----------TREEKWQSGSCDHVMNSKIYNKIQVNKCPLELRRKVVPETPHCNCISFDPKSDCSIGSGCFNVASKCECDPQICNLGDKCKNQNFVKRIYPKQYTFWANDRGWGLKADEFIKTKQFVNEYIGEIITMEESEKRILWANENNITDFYFMELDNGRLIDARQFSNLSRFINNSCDPNLVAEKWIVNREHRIGLFALRDIQKGEELTFQYNLQNKSSNRIVCKCFSVNCSGFLGEAPKMAXXXXXXXXXXXXXXXXXXXXXXXCKSFLTDKNSNSQCFRCGEIIDMLSSIVCSVGPCMKTYHSVCLNLNMANYVQSSWICPHHYCDVCARPSHHFSSNTTESYCNK 2774
C+ C + +++ C FH+ CL L E + C EC+ GI C+ C + ++ RC++ C K++H C++ P+ T F G CP H C C NPS P+ K++ C+ CP +H+GD C+ AG + + IIC H F AR + NV+WCF C +GG LLCCE+CPAA+H C +++ ++C DC + + +I+W+K G + WWP ++ H +NVP NI KH G+F V FFGS+DY W VF Y + D + +F ++EA + T+E + + H+ +K Y K+Q+ + E P CNC D ++ C S C N EC PQ+C G+ C+NQ F KR YP+ + +GWGL A I+ +FVNEY+GE+I EE RI A+EN+IT FY + +D R+IDA N SRF+N+SC PN KW VN + R+GLFA+ DI G ELTF YNL + + VC+C + NCSGFLG+ PK + + K K + S +CFRCG D ++C C K YH CL L + W CP H+CDVC +PS F S+C +
Sbjct: 670 CQLCEKPGSLLLCEGPCCGAFHLACL-GLSRRPEGRFT----CSECASGIHSCFVCKE-----SKTDVKRCVVTQCGKFYHEACVKKYPL---TVFESRG-FRCPLHSCVSCHASNPSNPRPSKGKMMRCVRCPVAYHSGDACLAAGCSVIASNSIICTAH--------------FTARKGKRHHAHV-----------------------NVSWCFVCSKGGSLLCCESCPAAFHPDCLNIEMPDGSWFCNDCRAGKKLHFQDIIWVKLGNYRWWPAEVCHPKNVPPNIQKMKHEIGEFPVFFFGSKDYYWTHQARVFPYMEGDRGSRYQGVRGIGRVFKNALQEAEARFREIKLQREARETQESERKPPPYKHIKVNKPYGKVQIYTAD-------ISEIPKCNCKPTD-ENPCGFDSECLNRMLMFECHPQVCPAGEFCQNQCFTKRQYPETKIIKTDGKGWGLVAKRDIRKGEFVNEYVGELIDEEECMARIKHAHENDITHFYMLTIDKDRIIDAGPKGNYSRFMNHSCQPNCETLKWTVNGDTRVGLFAVCDIPAGTELTFNYNLDCLGNEKTVCRCGASNCSGFLGDRPKTSTTLSSEEKGKKTKKKTRRRR----AKGEGKRQSEDECFRCG---DGGQLVLCDRKFCTKAYHLSCLGLGKRPF--GKWECPWHHCDVCGKPSTSFCHLCPNSFCKE 1306
BLAST of NSD-1 vs. Ensembl Human
Match: NSD2 (nuclear receptor binding SET domain protein 2 [Source:HGNC Symbol;Acc:HGNC:12766]) HSP 1 Score: 375.17 bits (962), Expect = 2.384e-116 Identity = 228/653 (34.92%), Postives = 322/653 (49.31%), Query Frame = 3
Query: 834 LGIIRCYACYKIVDISNEQGFMRCIIKTCTKWFHTNCLETGPMLEMTKFPKPGQLVCPCHICHKCELVNPS-PKYRCTKLIVCIMCPATFHTGDWCIPAGSVELNTGEIICPRHLVDLNFSMNIMVPPFVARVKSDLQERIYGNTLTKISEPMTITPSTVTKPTNVNWCFKCGEGGELLCCETCPAAYHFKCTDLKEIPQKFYCPDCASFCYRSYGEIVWIKCGTHPWWPGQILHLENVPKNIAAKKHANGQFVVQFFGSRDYMWRDHGNVFLYEKEDECNSKTSKYRYNNIFLEGIKEAAIGYVTREEKWQSGSCDHVMNSK---IYNKIQVNK--CPLELRRKVVPETPHCNCISFDPKSDCSIGSGCFNVASKCECDPQICNLGDKCKNQNFVKRIYPKQYTFWANDRGWGLKADEFIKTKQFVNEYIGEIITMEESEKRILWANENNITDFYFMELDNGRLIDARQFSNLSRFINNSCDPNLVAEKWIVNREHRIGLFALRDIQKGEELTFQYNLQNKSSNRIVCKCFSVNCSGFLGEAPKMAXXXXXXXXXXXXXXXXXXXXXXXCKSFLTDKNSNSQCFRCGEIIDMLSSIVCSVGPCMKTYHSVCLNLNMANYVQSSWICPHHYCDVCARPSHHFSSNTTESYCNK 2774
LGI C+ C + ++ RC++ C K++H C++ P+ T F G CP H C C NPS P+ K++ C+ CP +H+GD C+ AG + + IIC H F AR + NV+WCF C +GG LLCCE+CPAA+H C +++ ++C DC + + +I+W+K G + WWP ++ H +NVP NI KH G+F V FFGS+DY W VF Y + D + +F ++EA + RE K Q + + + + Y I+VNK +++ + E P CNC D ++ C S C N EC PQ+C G+ C+NQ F KR YP+ + +GWGL A I+ +FVNEY+GE+I EE RI A+EN+IT FY + +D R+IDA N SRF+N+SC PN KW VN + R+GLFA+ DI G ELTF YNL + + VC+C + NCSGFLG+ PK + + K K + S +CFRCG D ++C C K YH CL L + W CP H+CDVC +PS F S+C +
Sbjct: 60 LGIHSCFVCKE-----SKTDVKRCVVTQCGKFYHEACVKKYPL---TVFESRG-FRCPLHSCVSCHASNPSNPRPSKGKMMRCVRCPVAYHSGDACLAAGCSVIASNSIICTAH--------------FTARKGKRHHAHV-----------------------NVSWCFVCSKGGSLLCCESCPAAFHPDCLNIEMPDGSWFCNDCRAGKKLHFQDIIWVKLGNYRWWPAEVCHPKNVPPNIQKMKHEIGEFPVFFFGSKDYYWTHQARVFPYMEGDRGSRYQGVRGIGRVFKNALQEAEARF--REIKLQREARETQESERKPPPYKHIKVNKPYGKVQIYTADISEIPKCNCKPTD-ENPCGFDSECLNRMLMFECHPQVCPAGEFCQNQCFTKRQYPETKIIKTDGKGWGLVAKRDIRKGEFVNEYVGELIDEEECMARIKHAHENDITHFYMLTIDKDRIIDAGPKGNYSRFMNHSCQPNCETLKWTVNGDTRVGLFAVCDIPAGTELTFNYNLDCLGNEKTVCRCGASNCSGFLGDRPKTSTTLSSEEKGKKTKKKTRRRR----AKGEGKRQSEDECFRCG---DGGQLVLCDRKFCTKAYHLSCLGLGKRPF--GKWECPWHHCDVCGKPSTSFCHLCPNSFCKE 654
BLAST of NSD-1 vs. Ensembl Celegans
Match: met-1 (Histone-lysine N-methyltransferase [Source:UniProtKB/TrEMBL;Acc:A4LBC2]) HSP 1 Score: 112.079 bits (279), Expect = 1.167e-24 Identity = 73/183 (39.89%), Postives = 101/183 (55.19%), Query Frame = 3
Query: 1923 CFNVASKCECDPQICNLGDKCKNQNFVKRIYPKQYTF-WANDRGWGLKADEFIKTKQFVNEYIGEIITMEESEKR-ILWANENNITDFYFMELDNG-RLIDARQFSNLSRFINNSCDPNLVAEKWIVNRE----HRIGLFALRDIQKGEELTFQYNLQNKSSNRIVCKCFSVNCSGFLGEAPK 2450
C N A EC P C + KCKNQ F K+ Y F +G GL+A + IK +F+ EYIGE++ ++ EKR +A + Y D G IDA + N SRF+N+SCDPN + EKW V R +R+G F+ R I+ GEE+TF Y N + C C S +CSG++G+ P+
Sbjct: 641 CVNRAMLTEC-PSSCQV--KCKNQRFAKKKYAAVEAFHTGTAKGCGLRAVKDIKKGRFIIEYIGEVVERDDYEKRKTKYAADKKHKHHYL--CDTGVYTIDATVYGNPSRFVNHSCDPNAICEKWSVPRTPGDVNRVGFFSKRFIKAGEEITFDYQFVNYGRDAQQCFCGSASCSGWIGQKPE 818
BLAST of NSD-1 vs. Ensembl Celegans
Match: met-1 (Histone-lysine N-methyltransferase [Source:UniProtKB/TrEMBL;Acc:A4LBC2]) HSP 1 Score: 112.079 bits (279), Expect = 1.201e-24 Identity = 73/183 (39.89%), Postives = 101/183 (55.19%), Query Frame = 3
Query: 1923 CFNVASKCECDPQICNLGDKCKNQNFVKRIYPKQYTF-WANDRGWGLKADEFIKTKQFVNEYIGEIITMEESEKR-ILWANENNITDFYFMELDNG-RLIDARQFSNLSRFINNSCDPNLVAEKWIVNRE----HRIGLFALRDIQKGEELTFQYNLQNKSSNRIVCKCFSVNCSGFLGEAPK 2450
C N A EC P C + KCKNQ F K+ Y F +G GL+A + IK +F+ EYIGE++ ++ EKR +A + Y D G IDA + N SRF+N+SCDPN + EKW V R +R+G F+ R I+ GEE+TF Y N + C C S +CSG++G+ P+
Sbjct: 655 CVNRAMLTEC-PSSCQV--KCKNQRFAKKKYAAVEAFHTGTAKGCGLRAVKDIKKGRFIIEYIGEVVERDDYEKRKTKYAADKKHKHHYL--CDTGVYTIDATVYGNPSRFVNHSCDPNAICEKWSVPRTPGDVNRVGFFSKRFIKAGEEITFDYQFVNYGRDAQQCFCGSASCSGWIGQKPE 832
BLAST of NSD-1 vs. Ensembl Celegans
Match: mes-4 (Histone-lysine N-methyltransferase mes-4 [Source:UniProtKB/Swiss-Prot;Acc:Q9NH52]) HSP 1 Score: 102.064 bits (253), Expect = 8.868e-22 Identity = 131/535 (24.49%), Postives = 221/535 (41.31%), Query Frame = 3
Query: 990 GQLVCPCHICHKCELVNPSPKYRCTKLIVCIMCPATFHTGDWCIPAGSVELNTG-----------EIICPRHLVDLNFSMNIMVPPFVARVKSDLQERIYGNTLTKISEPMTITP-STVTKPTNVNWCFKCG----EGGELLCCETCPAAYHFKCTDL-----KEIPQKFYCPDCASFCYRSYGEIVWIKCGTHPWWPGQILHLENVPK----NIAAKKHANGQFVVQFFGSRDYMWRDHGNVFLYEKEDECN--------SKTSKYRYNNIFLEGIKEAAIGYVTREEKWQSGSCDHVMNSKIYNKIQVN---KCPLELRRKVVPETPHCNCISFDPKSDCSIGSGCFNVASKCECDPQICNLGDKCKNQNFVKRIYPKQYTFWAND-RGWGLKADEFIKTKQFVNEYIGEIITMEESEKRI--LWANENNITDFYFMELDNGRLIDARQFSNLSRFINNSCDPNLVA--EKWIVNREHRIGLF-------ALRDIQKGEELTFQYNLQNKSSNRIVCKCFSVNCSGFLGEAPK 2450
+L+CP H C+ C L + + C +C FH C P+G +LN IICP H + +D+Q + N K +T+ P + VT +++ C G + + C+TC ++H C ++ K IP C C ++ K + +W L P NI ++ G VVQ+ ++ + + D +K S R N++ E +E A + R C +V + ++ +++ + KC +L E CNC D + S C +A EC P C+ C N+ I ++ A +G+G+ A I+ +++ EY+GEII E ++R+ + + + + Y MEL G +DA ++ N+SR+IN+SCDPN + K V + L+ A+R I G+E+TF YN+ N+ N C+C + NC G +G+A +
Sbjct: 199 ARLLCPLHCCNSCNLDHHKQSAYVGDIAECALCLRAFHLTS-CYPSGGRDLNVSITIGGKVEKFEMIICPAHYLP----------------GADVQ---FYNKHKKRKNAVTVVPKADVTMKSHIKACCVIGCEKSSNSKTIMCKTCCRSFHSGCREVETLNGKPIPDD-QCESCVCGDPIPQNTLILAKWTDNSFWLALTLDWYKYPTGNRGNINFERL--GYTVVQWLIPQENDKEKQPLMSIVPVSDIARLTKNYFSLAKNSTLR--NLWEEKYEEQADTALKR--------CPYVCKT-VFGRLRTSVYYKCEPKLEEYHNNEV--CNCEGADRCTKLS----CQYLADDYECPPS-CSKKGVCHNRQVSMGIVSEKIKLAATLCKGYGVFAKGQIEKDEYICEYVGEIIDKAEKKRRLDSVSISRDFQANHYMMELHKGLTVDAARYGNISRYINHSCDPNAASFVTKVFVKKTKEGSLYDTRSYIRAIRTIDDGDEITFSYNMNNE-ENLPDCECGAENCMGTMGKAKR 691
BLAST of NSD-1 vs. Ensembl Celegans
Match: set-12 (Histone-lysine N-methyltransferase [Source:UniProtKB/TrEMBL;Acc:Q21404]) HSP 1 Score: 96.6709 bits (239), Expect = 6.439e-21 Identity = 66/184 (35.87%), Postives = 99/184 (53.80%), Query Frame = 3
Query: 1899 SDCSIGSGCFNVASKCECDPQICNLGDKCKNQNFVKRIYPKQYTFWA-NDRGWGLKADEFIKTKQFVNEYIGEIITMEESEKRILWANENNITDFYFMELDNGRLIDARQFSNLSRFINNSCDPNLVAEKWIV-NREHR-IGLFALRDIQKGEELTFQYNLQNKSSNRIVCKCFSVNCSGFLGE 2441
+DC+ C N A+ EC P+ C+ C+NQ F KR + TF N G GL+A E I T + + EY GE IT E KR+ ++ I Y E+ +D + N +RFIN+SC+PN + + W V +R + +G+FA + I+ GEE+TF Y + N C+C C G++G+
Sbjct: 61 TDCTTEE-CSNFANHREC-PRGCS---NCENQRFRKRQFCGVETFLTDNGIGHGLRATEEIATGKLILEYRGEAITKAEHNKRVKRYKKDGIKHSYSFEVGRNYYVDPTRKGNSARFINHSCNPNALVKVWTVPDRPMKSLGIFASKVIKPGEEITFDYGTSFR--NDQPCQCGEAACRGWIGK 237
BLAST of NSD-1 vs. Ensembl Celegans
Match: set-2 (Histone-lysine N-methyltransferase set-2 [Source:UniProtKB/Swiss-Prot;Acc:Q18221]) HSP 1 Score: 83.1889 bits (204), Expect = 4.795e-16 Identity = 55/163 (33.74%), Postives = 84/163 (51.53%), Query Frame = 3
Query: 1962 ICNLGDKCKNQNFVK---RIYPKQYTFWANDR--GWGLKADEFIKTKQFVNEYIGEIITMEESEKRILWANENNITDFYFMELDNGRLIDARQFSNLSRFINNSCDPNLVAEKWIVNREHRIGLFALRDIQKGEELTFQYNLQNKSSNRIVCKCFSVNCSGFL 2435
+ +LGD N +F K + K+ +A R GWGL A E I + + EYIG+ I +E+R I Y +D +IDA + N +RFIN+SC PN A+ + E RI +++ I+KGEE+T+ Y + ++I C C + C G+L
Sbjct: 579 LTSLGDA--NNDFFKINQLKFRKKMIKFARSRIHGWGLYAMESIAPDEMIVEYIGQTIRSLVAEEREKAYERRGIGSSYLFRIDLHHVIDATKRGNFARFINHSCQPNCYAKVLTIEGEKRIVIYSRTIIKKGEEITYDYKFPIE-DDKIDCLCGAKTCRGYL 738
BLAST of NSD-1 vs. Ensembl Fly
Match: NSD (gene:FBgn0039559 transcript:FBtr0085267) HSP 1 Score: 296.975 bits (759), Expect = 1.121e-83 Identity = 181/530 (34.15%), Postives = 262/530 (49.43%), Query Frame = 3
Query: 885 EQGFMRCIIKTCTKWFHTNCLETGPMLEMTKFPKPGQLVCPCHICHKCELVNPSPKYR---CTKLIVCIMCPATFHTGDWCIPAGSVELNTGEIICPRHLVDLNFSMNIMVPPFVARVKSDLQERIYGNTLTKISEPMTITPSTVTKPTNVNWCFKCGEGGELLCCETCPAAYHFKCTDLK-EIPQKFYCPDCASFCYRSYGEIVWIKCGTHPWWPGQILHLENVPKNIAAKKHANGQFVVQFFGSRDYMWRDHGNVFLYEKEDECNSKTSKYRYNNIFLEGIKEAA----IGYVTREEKWQSGSCDHVMNSKIYNKIQVNKCPLELR-RKVVPETPHCNCISFDPKSDCSIGSGCFNVASKCECDPQICNLGDKCKNQNFVKRIYPKQYTFWANDRGWGLKADEFIKTKQFVNEYIGEIITMEESEKRILWANENNITDFYFMELDNGRLIDARQFSNLSRFINNSCDPNLVAEKWIVNREHRIGLFALRDIQKGEELTFQY---NLQNKSSNRIVCKCFSVNCSGFLG 2438
E + C C K FHT+C + P +K CP H+CH C +PS K++ +KL C+ CPAT+H CIPAG+ LNT IICPRH + K+D NV WC+ C +GGEL+CCETCP A H C ++ + + + C +C S YGEIVW K WWP IL VP NI K H FVV+FFG+ D+ W V+LY + D + +K + + G++EA+ I R+E+ + ++ Y KI+ NK LR + + + CNC+ D + C +GC N EC+P+ C G C+N+ F +R P+ + N+RG+GL E I FV EY+GE+I E ++R+ + ++YF+ ++ +IDA NL+RF+N+SC+PN +KW VN HR+G+FA++DI ELTF Y +L N S + C C + CSG +G
Sbjct: 894 EDKLLTCSQPMCGKRFHTSCCKYWPQASSSKH----SARCPRHVCHTCVSDDPSGKFQQLGSSKLAKCVRCPATYHQLSKCIPAGTQMLNTTNIICPRHNI----------------AKADAH-------------------------VNVLWCYICVKGGELVCCETCPIAVHAHCRNIPIKTNESYICEECESGRLPLYGEIVWAKFNNFRWWPAIILPPTEVPSNILKKAHGENDFVVRFFGTHDHGWISRRRVYLYIEGDTGDGHKTKSQLFRNYTTGVEEASRFLPIIKARRQEQDMERQSGNKLHPPPYVKIKTNKAVPPLRFSQNLEDLSTCNCLPVD-EHPCGPEAGCLNRMLFNECNPEYCKAGSLCENRMFEQRKSPRLEVVYMNERGFGLVNREPIAVGDFVIEYVGEVINHAEFQRRMEQKQRDRDENYYFLGVEKDFIIDAGPKGNLARFMNHSCEPNCETQKWTVNCIHRVGIFAIKDIPVNSELTFNYLWDDLMNNS--KKACFCGAKRCSGEIG 1375
BLAST of NSD-1 vs. Ensembl Fly
Match: NSD (gene:FBgn0039559 transcript:FBtr0335014) HSP 1 Score: 296.975 bits (759), Expect = 1.167e-83 Identity = 181/530 (34.15%), Postives = 262/530 (49.43%), Query Frame = 3
Query: 885 EQGFMRCIIKTCTKWFHTNCLETGPMLEMTKFPKPGQLVCPCHICHKCELVNPSPKYR---CTKLIVCIMCPATFHTGDWCIPAGSVELNTGEIICPRHLVDLNFSMNIMVPPFVARVKSDLQERIYGNTLTKISEPMTITPSTVTKPTNVNWCFKCGEGGELLCCETCPAAYHFKCTDLK-EIPQKFYCPDCASFCYRSYGEIVWIKCGTHPWWPGQILHLENVPKNIAAKKHANGQFVVQFFGSRDYMWRDHGNVFLYEKEDECNSKTSKYRYNNIFLEGIKEAA----IGYVTREEKWQSGSCDHVMNSKIYNKIQVNKCPLELR-RKVVPETPHCNCISFDPKSDCSIGSGCFNVASKCECDPQICNLGDKCKNQNFVKRIYPKQYTFWANDRGWGLKADEFIKTKQFVNEYIGEIITMEESEKRILWANENNITDFYFMELDNGRLIDARQFSNLSRFINNSCDPNLVAEKWIVNREHRIGLFALRDIQKGEELTFQY---NLQNKSSNRIVCKCFSVNCSGFLG 2438
E + C C K FHT+C + P +K CP H+CH C +PS K++ +KL C+ CPAT+H CIPAG+ LNT IICPRH + K+D NV WC+ C +GGEL+CCETCP A H C ++ + + + C +C S YGEIVW K WWP IL VP NI K H FVV+FFG+ D+ W V+LY + D + +K + + G++EA+ I R+E+ + ++ Y KI+ NK LR + + + CNC+ D + C +GC N EC+P+ C G C+N+ F +R P+ + N+RG+GL E I FV EY+GE+I E ++R+ + ++YF+ ++ +IDA NL+RF+N+SC+PN +KW VN HR+G+FA++DI ELTF Y +L N S + C C + CSG +G
Sbjct: 890 EDKLLTCSQPMCGKRFHTSCCKYWPQASSSKH----SARCPRHVCHTCVSDDPSGKFQQLGSSKLAKCVRCPATYHQLSKCIPAGTQMLNTTNIICPRHNI----------------AKADAH-------------------------VNVLWCYICVKGGELVCCETCPIAVHAHCRNIPIKTNESYICEECESGRLPLYGEIVWAKFNNFRWWPAIILPPTEVPSNILKKAHGENDFVVRFFGTHDHGWISRRRVYLYIEGDTGDGHKTKSQLFRNYTTGVEEASRFLPIIKARRQEQDMERQSGNKLHPPPYVKIKTNKAVPPLRFSQNLEDLSTCNCLPVD-EHPCGPEAGCLNRMLFNECNPEYCKAGSLCENRMFEQRKSPRLEVVYMNERGFGLVNREPIAVGDFVIEYVGEVINHAEFQRRMEQKQRDRDENYYFLGVEKDFIIDAGPKGNLARFMNHSCEPNCETQKWTVNCIHRVGIFAIKDIPVNSELTFNYLWDDLMNNS--KKACFCGAKRCSGEIG 1371
BLAST of NSD-1 vs. Ensembl Fly
Match: Set2 (gene:FBgn0030486 transcript:FBtr0301559) HSP 1 Score: 139.428 bits (350), Expect = 6.365e-33 Identity = 74/206 (35.92%), Postives = 108/206 (52.43%), Query Frame = 3
Query: 1845 RKVVPETPHCNCISF-----DPKSDCSIGSGCFNVASKCECDPQICNLGDKCKNQNFVKRIYPKQYTFWANDRGWGLKADEFIKTKQFVNEYIGEIITMEESEKRILWANENNITDFYFMELDNGRLIDARQFSNLSRFINNSCDPNLVAEKWIVNREHRIGLFALRDIQKGEELTFQYNLQNKSSNRIVCKCFSVNCSGFLGEAP 2447
R+V E C F + + S G+GC N EC P +C+ G +C N+ F + F +G G+ A+ I +F+ EY+GE+I EE E+R +++ +YFM L +IDA N+SR+IN+SCDPN +KW VN E RIG F+++ IQ GEE+TF Y + C C + NC G++G P
Sbjct: 1301 RQVSQENAEMQCDCFLTGDEEAQGHLSCGAGCINRMLMIECGP-LCSNGARCTNKRFQQHQCWPCRVFRTEKKGCGITAELLIPPGEFIMEYVGEVIDSEEFERRQHLYSKDRNRHYYFMALRGEAVIDATSKGNISRYINHSCDPNAETQKWTVNGELRIGFFSVKPIQPGEEITFDYQYLRYGRDAQRCYCEAANCRGWIGGEP 1505
BLAST of NSD-1 vs. Ensembl Fly
Match: Set2 (gene:FBgn0030486 transcript:FBtr0073779) HSP 1 Score: 139.428 bits (350), Expect = 6.577e-33 Identity = 74/206 (35.92%), Postives = 108/206 (52.43%), Query Frame = 3
Query: 1845 RKVVPETPHCNCISF-----DPKSDCSIGSGCFNVASKCECDPQICNLGDKCKNQNFVKRIYPKQYTFWANDRGWGLKADEFIKTKQFVNEYIGEIITMEESEKRILWANENNITDFYFMELDNGRLIDARQFSNLSRFINNSCDPNLVAEKWIVNREHRIGLFALRDIQKGEELTFQYNLQNKSSNRIVCKCFSVNCSGFLGEAP 2447
R+V E C F + + S G+GC N EC P +C+ G +C N+ F + F +G G+ A+ I +F+ EY+GE+I EE E+R +++ +YFM L +IDA N+SR+IN+SCDPN +KW VN E RIG F+++ IQ GEE+TF Y + C C + NC G++G P
Sbjct: 1350 RQVSQENAEMQCDCFLTGDEEAQGHLSCGAGCINRMLMIECGP-LCSNGARCTNKRFQQHQCWPCRVFRTEKKGCGITAELLIPPGEFIMEYVGEVIDSEEFERRQHLYSKDRNRHYYFMALRGEAVIDATSKGNISRYINHSCDPNAETQKWTVNGELRIGFFSVKPIQPGEEITFDYQYLRYGRDAQRCYCEAANCRGWIGGEP 1554
BLAST of NSD-1 vs. Ensembl Fly
Match: ash1 (gene:FBgn0005386 transcript:FBtr0306009) HSP 1 Score: 128.642 bits (322), Expect = 1.392e-29 Identity = 79/223 (35.43%), Postives = 120/223 (53.81%), Query Frame = 3
Query: 1782 HVMNSKIYNKIQVNKCPLELRRKVVP-ETPHCNCISFDPKSDCSIGSGCFNVASKCECDPQICNLGDKCKNQNFVKR-IYPKQYTFWANDRGWGLKADEFIKTKQFVNEYIGEIITMEESEKRILWANENNITDFYFMELDNGRLIDARQFSNLSRFINNSCDPNLVAEKWIVNREHRIGLFALRDIQKGEELTFQYN--LQNKSSNRIVCKCFSVNCSGFLG 2438
+V+ S Y KI+ N +R + + P CNC + KS C C N EC P C G+KC+NQ + + P F D+GWG++ I ++ EY+GE++T +E ++R+ N+ T Y + LD G +ID ++ + RF+N+SC+PN +KW VN R+ LFA R I++GEELT+ YN L N S + C+C + C G +G
Sbjct: 1313 NVVPSWNYRKIRTNVYAESVRPNLAGFDHPTCNCKNQGEKS-CL--DNCLNRMVYTECSPSNCPAGEKCRNQKIQRHAVAPGVERFMTADKGWGVRTKLPIAKGTYILEYVGEVVTEKEFKQRMASIYLND-THHYCLHLDGGLVIDGQRMGSDCRFVNHSCEPNCEMQKWSVNGLSRMVLFAKRAIEEGEELTYDYNFSLFNPSEGQ-PCRCNTPQCRGVIG 1530
BLAST of NSD-1 vs. Ensembl Zebrafish
Match: nsd1b (nuclear receptor binding SET domain protein 1b [Source:ZFIN;Acc:ZDB-GENE-080519-2]) HSP 1 Score: 387.497 bits (994), Expect = 6.227e-115 Identity = 238/700 (34.00%), Postives = 346/700 (49.43%), Query Frame = 3
Query: 693 CRYCLETKNIVQCNKCLFNNFHVKCLEFLQNSIETKINDLDRCLECSLGIIRCYACYKIVDISNEQGFMRCIIKTCTKWFHTNCLET-GPMLEMTKFPKPGQLVCPCHICHKCELVNPS-PKYRCTKLIVCIMCPATFHTGDWCIPAGSVELNTGEIICPRHLVDLNFSMNIMVPPFVARVKSDLQERIYGNTLTKISEPMTITPSTVTKPTNVNWCFKCGEGGELLCCETCPAAYHFKCTDLKEIPQKFYCPDCASFCYRSYGEIVWIKCGTHPWWPGQILHLENVPKNIAAKKHANGQFVVQFFGSRDYMWRDHGNVFLYEKEDECNSKTSKYRYNNIFLEGIKEAAIGY--VTREEKWQSGSCDHVMNSKI--YNKIQVNK--CPLELRRKVVPETPHCNCISFDPKSDCSIGSGCFNVASKCECDPQICNLGDKCKNQNFVKRIYPKQYTFWANDRGWGLKADEFIKTKQFVNEYIGEIITMEESEKRILWANENNITDFYFMELDNGRLIDARQFSNLSRFINNSCDPNLVAEKWIVNREHRIGLFALRDIQKGEELTFQYNLQNKSSNRIVCKCFSVNCSGFLGEAPKMAXXXXXXXXXXXXXXXXXXXXXXXCKSFLTDKNSNSQCFRCGEIIDMLSSIVCSVGPCMKTYHSVCLNLNMANYVQSSWICPHHYCDVCARPSHHFSSNTTESYC 2768
C C + +++ C FH +C + + C EC+ G+ C+AC ++ + RC++ C K++H C + P + + + CP H C C ++NP+ P +L CI CP +H+ D+CIPAGSV L I+CP H F R E + NV+WCF C EGG LLCCE+CPAA+H +C ++ +YC DC + Y E+VW+K G + WWP ++ + +++P+NI KH G+F V FFGS DY+W VF Y + D + + ++ + + + EAA+ + + E++ + D + K Y +I+VNK + + + E P CNC + D ++ C + S C N EC PQ+C G++C+NQ F+KR Y + TF RGWGL+ IK F++EY+GE+I EE RI A ENNI +FY + LD R+IDA N +RF+N+ C PN +KW VN + R+GLF+L DI G ELTF YNL+ + + VCKC + NCSGFLG PK S K KK + E K +CF CG+ ++S C C K YH+ CLNL W CP H CD+C + + F SYC
Sbjct: 724 CPMCEKQGDLLLCEGQCCGAFHPQCTGLNEPPTGKFL-----CQECTSGVHSCFACKRL-----GEDVRRCMVPGCGKFYHGECAASHAPTVPLNR-----AFRCPLHACLSCFILNPANPSVAKGQLTRCIRCPVAYHSSDFCIPAGSVTLTDSNIVCPNH--------------FTPRKGCRNHEHV-----------------------NVSWCFVCSEGGSLLCCESCPAAFHRECLNIDMPEGSWYCNDCRAGKKPHYKEVVWVKVGRYRWWPAEVSNPKDIPENILRMKHDVGEFPVLFFGSNDYLWTYQARVFPYMEGDANSKEKMGKGVDSTYKKALDEAALRFKELQAEKELRQLQEDRRNDKKPPPYKQIKVNKPFGKVLIISADLSEIPRCNCKATD-ENPCGMDSECINRMLLYECHPQVCPAGERCQNQCFIKRQYCQVETFRTLSRGWGLRCVHDIKKGGFISEYVGEVIDEEECRARIKHAQENNIGNFYMLTLDKDRIIDAGPKGNEARFMNHCCQPNCETQKWTVNGDTRVGLFSLTDIPAGTELTFNYNLECLGNGKTVCKCGASNCSGFLGVRPKNNPPSDDKGRKLKKKRKSQQEVI---------KEREDECFSCGDGGQIVS---CKRPGCPKVYHADCLNL--TKRPAGRWECPWHQCDLCGQEAASFCEMCPSSYC 1356
BLAST of NSD-1 vs. Ensembl Zebrafish
Match: nsd1a (nuclear receptor binding SET domain protein 1a [Source:ZFIN;Acc:ZDB-GENE-080519-3]) HSP 1 Score: 389.037 bits (998), Expect = 4.521e-114 Identity = 244/715 (34.13%), Postives = 358/715 (50.07%), Query Frame = 3
Query: 693 CRYCLETKNIVQCNKCLFNNFHVKCLEFLQNSIETKINDLDRCLECSLGIIRCYACYKIVDISNEQGFMRCIIKTCTKWFHTNC-LETGPMLEMTKFPKPGQLVCPCHICHKCELVNPS-PKYRCTKLIVCIMCPATFHTGDWCIPAGSVELNTGEIICPRHLVDLNFSMNIMVPPFVARVKSDLQERIYGNTLTKISEPMTITPSTVTKPTNVNWCFKCGEGGELLCCETCPAAYHFKCTDLKEIPQ-KFYCPDCASFCYRSYGEIVWIKCGTHPWWPGQILHLENVPKNIAAKKHANGQFVVQFFGSRDYMWRDHGNVFLYEKEDECNSKTSKYRYNNIFLEGIKEAAIGY--VTREEKWQSGSCDHVMNSKI--YNKIQVNK--CPLELRRKVVPETPHCNCISFDPKSDCSIGSGCFNVASKCECDPQICNLGDKCKNQNFVKRIYPKQYTFWANDRGWGLKADEFIKTKQFVNEYIGEIITMEESEKRILWANENNITDFYFMELDNGRLIDARQFSNLSRFINNSCDPNLVAEKWIVNREHRIGLFALRDIQKGEELTFQYNLQNKSSNRIVCKCFSVNCSGFLGEAPKMAXXXXXXXXXXXXXXXXXXXXXXXCKSFLTDKNSNSQCFRCGEIIDMLSSIVCSVGPCMKTYHSVCLNLNMANYVQSSWICPHHYCDVCARPSHHFSSNTTESYCNKD-----FIKKFN 2795
C+ C +T ++ C FH++C+ + I C EC +G+ C+ C K ++ RC+I C K++H +C L+ P + + C H+C C + NP+ P +L C+ CP +H D+C+ AGSV L +CP H F R E I NV+WCF C EGG LLCCE+CPAA+H +C ++ E+PQ ++C DC + Y +I+W+K G + WWP ++ ++VP+NI+ KH G+F V FFGS+DY+W F Y + D N + + ++ + + EAA + + +E++ + D + K Y I+VNK + + + E P CNC + D ++ C I S C N EC Q+C G++C+NQ+F KR Y + F RGWGL++ IK FVNEY+GE+I EE RI A +N+I +FY + LD R+IDA N SRF+N+SC PN +KW VN + R+GLFAL DI KG ELTF YNL+ + + VCKC + NCSGFLG PK ++ SD + + +S +T K +CF CG+ ++S C C K YH+ CLNL + W CP H C+ C R + + SYC + FI K +
Sbjct: 1245 CQVCEKTGELLLCEGQCCGAFHLQCIGLTETPKGRFI-----CQECKMGVHTCFVCKKP-----DKEVRRCMIPVCGKFYHMDCILKYSPTVAQNRG-----FRCSIHVCLSCYITNPNNPGISKGRLTRCVRCPVAYHANDYCMAAGSVPLANNSFLCPNH--------------FTPRKGCKNHEHI-----------------------NVSWCFVCSEGGSLLCCESCPAAFHRECLNI-EMPQGSWFCNDCRAGKKPHYKDILWVKVGRYRWWPAEVTQPKSVPENISRMKHEVGEFPVHFFGSKDYVWTYQARCFPYMEGDANNKEKMGKGADAVYKKALNEAADRFRELLKEKEMRQLQEDRKNDKKPPPYKHIKVNKQIGKVLIITADLSEIPRCNCKATD-ENPCGIDSECINRMLLYECHSQVCPAGERCQNQSFTKRQYTEVEIFRTLSRGWGLRSISDIKKGAFVNEYVGEVIDEEECRSRIKNAQDNDICNFYMLTLDKDRIIDAGPKGNESRFMNHSCQPNCETQKWTVNGDTRVGLFALEDIPKGVELTFNYNLECLGNGKTVCKCGAPNCSGFLGVRPK----NQPPSDDKTRKLRRKVSGKRKSQSEVT-KEREDECFYCGDGGQIVS---CKKPGCPKVYHADCLNL--SKRPAGRWECPWHQCNECGREAASYCEMCPNSYCEQHREGMLFISKLD 1895
BLAST of NSD-1 vs. Ensembl Zebrafish
Match: nsd1a (nuclear receptor binding SET domain protein 1a [Source:ZFIN;Acc:ZDB-GENE-080519-3]) HSP 1 Score: 388.652 bits (997), Expect = 5.643e-114 Identity = 244/715 (34.13%), Postives = 358/715 (50.07%), Query Frame = 3
Query: 693 CRYCLETKNIVQCNKCLFNNFHVKCLEFLQNSIETKINDLDRCLECSLGIIRCYACYKIVDISNEQGFMRCIIKTCTKWFHTNC-LETGPMLEMTKFPKPGQLVCPCHICHKCELVNPS-PKYRCTKLIVCIMCPATFHTGDWCIPAGSVELNTGEIICPRHLVDLNFSMNIMVPPFVARVKSDLQERIYGNTLTKISEPMTITPSTVTKPTNVNWCFKCGEGGELLCCETCPAAYHFKCTDLKEIPQ-KFYCPDCASFCYRSYGEIVWIKCGTHPWWPGQILHLENVPKNIAAKKHANGQFVVQFFGSRDYMWRDHGNVFLYEKEDECNSKTSKYRYNNIFLEGIKEAAIGY--VTREEKWQSGSCDHVMNSKI--YNKIQVNK--CPLELRRKVVPETPHCNCISFDPKSDCSIGSGCFNVASKCECDPQICNLGDKCKNQNFVKRIYPKQYTFWANDRGWGLKADEFIKTKQFVNEYIGEIITMEESEKRILWANENNITDFYFMELDNGRLIDARQFSNLSRFINNSCDPNLVAEKWIVNREHRIGLFALRDIQKGEELTFQYNLQNKSSNRIVCKCFSVNCSGFLGEAPKMAXXXXXXXXXXXXXXXXXXXXXXXCKSFLTDKNSNSQCFRCGEIIDMLSSIVCSVGPCMKTYHSVCLNLNMANYVQSSWICPHHYCDVCARPSHHFSSNTTESYCNKD-----FIKKFN 2795
C+ C +T ++ C FH++C+ + I C EC +G+ C+ C K ++ RC+I C K++H +C L+ P + + C H+C C + NP+ P +L C+ CP +H D+C+ AGSV L +CP H F R E I NV+WCF C EGG LLCCE+CPAA+H +C ++ E+PQ ++C DC + Y +I+W+K G + WWP ++ ++VP+NI+ KH G+F V FFGS+DY+W F Y + D N + + ++ + + EAA + + +E++ + D + K Y I+VNK + + + E P CNC + D ++ C I S C N EC Q+C G++C+NQ+F KR Y + F RGWGL++ IK FVNEY+GE+I EE RI A +N+I +FY + LD R+IDA N SRF+N+SC PN +KW VN + R+GLFAL DI KG ELTF YNL+ + + VCKC + NCSGFLG PK ++ SD + + +S +T K +CF CG+ ++S C C K YH+ CLNL + W CP H C+ C R + + SYC + FI K +
Sbjct: 1229 CQVCEKTGELLLCEGQCCGAFHLQCIGLTETPKGRFI-----CQECKMGVHTCFVCKKP-----DKEVRRCMIPVCGKFYHMDCILKYSPTVAQNRG-----FRCSIHVCLSCYITNPNNPGISKGRLTRCVRCPVAYHANDYCMAAGSVPLANNSFLCPNH--------------FTPRKGCKNHEHI-----------------------NVSWCFVCSEGGSLLCCESCPAAFHRECLNI-EMPQGSWFCNDCRAGKKPHYKDILWVKVGRYRWWPAEVTQPKSVPENISRMKHEVGEFPVHFFGSKDYVWTYQARCFPYMEGDANNKEKMGKGADAVYKKALNEAADRFRELLKEKEMRQLQEDRKNDKKPPPYKHIKVNKQIGKVLIITADLSEIPRCNCKATD-ENPCGIDSECINRMLLYECHSQVCPAGERCQNQSFTKRQYTEVEIFRTLSRGWGLRSISDIKKGAFVNEYVGEVIDEEECRSRIKNAQDNDICNFYMLTLDKDRIIDAGPKGNESRFMNHSCQPNCETQKWTVNGDTRVGLFALEDIPKGVELTFNYNLECLGNGKTVCKCGAPNCSGFLGVRPK----NQPPSDDKTRKLRRKVSGKRKSQSEVT-KEREDECFYCGDGGQIVS---CKKPGCPKVYHADCLNL--SKRPAGRWECPWHQCNECGREAASYCEMCPNSYCEQHREGMLFISKLD 1879
BLAST of NSD-1 vs. Ensembl Zebrafish
Match: nsd1b (nuclear receptor binding SET domain protein 1b [Source:ZFIN;Acc:ZDB-GENE-080519-2]) HSP 1 Score: 387.497 bits (994), Expect = 7.773e-114 Identity = 238/700 (34.00%), Postives = 346/700 (49.43%), Query Frame = 3
Query: 693 CRYCLETKNIVQCNKCLFNNFHVKCLEFLQNSIETKINDLDRCLECSLGIIRCYACYKIVDISNEQGFMRCIIKTCTKWFHTNCLET-GPMLEMTKFPKPGQLVCPCHICHKCELVNPS-PKYRCTKLIVCIMCPATFHTGDWCIPAGSVELNTGEIICPRHLVDLNFSMNIMVPPFVARVKSDLQERIYGNTLTKISEPMTITPSTVTKPTNVNWCFKCGEGGELLCCETCPAAYHFKCTDLKEIPQKFYCPDCASFCYRSYGEIVWIKCGTHPWWPGQILHLENVPKNIAAKKHANGQFVVQFFGSRDYMWRDHGNVFLYEKEDECNSKTSKYRYNNIFLEGIKEAAIGY--VTREEKWQSGSCDHVMNSKI--YNKIQVNK--CPLELRRKVVPETPHCNCISFDPKSDCSIGSGCFNVASKCECDPQICNLGDKCKNQNFVKRIYPKQYTFWANDRGWGLKADEFIKTKQFVNEYIGEIITMEESEKRILWANENNITDFYFMELDNGRLIDARQFSNLSRFINNSCDPNLVAEKWIVNREHRIGLFALRDIQKGEELTFQYNLQNKSSNRIVCKCFSVNCSGFLGEAPKMAXXXXXXXXXXXXXXXXXXXXXXXCKSFLTDKNSNSQCFRCGEIIDMLSSIVCSVGPCMKTYHSVCLNLNMANYVQSSWICPHHYCDVCARPSHHFSSNTTESYC 2768
C C + +++ C FH +C + + C EC+ G+ C+AC ++ + RC++ C K++H C + P + + + CP H C C ++NP+ P +L CI CP +H+ D+CIPAGSV L I+CP H F R E + NV+WCF C EGG LLCCE+CPAA+H +C ++ +YC DC + Y E+VW+K G + WWP ++ + +++P+NI KH G+F V FFGS DY+W VF Y + D + + ++ + + + EAA+ + + E++ + D + K Y +I+VNK + + + E P CNC + D ++ C + S C N EC PQ+C G++C+NQ F+KR Y + TF RGWGL+ IK F++EY+GE+I EE RI A ENNI +FY + LD R+IDA N +RF+N+ C PN +KW VN + R+GLF+L DI G ELTF YNL+ + + VCKC + NCSGFLG PK S K KK + E K +CF CG+ ++S C C K YH+ CLNL W CP H CD+C + + F SYC
Sbjct: 1099 CPMCEKQGDLLLCEGQCCGAFHPQCTGLNEPPTGKFL-----CQECTSGVHSCFACKRL-----GEDVRRCMVPGCGKFYHGECAASHAPTVPLNR-----AFRCPLHACLSCFILNPANPSVAKGQLTRCIRCPVAYHSSDFCIPAGSVTLTDSNIVCPNH--------------FTPRKGCRNHEHV-----------------------NVSWCFVCSEGGSLLCCESCPAAFHRECLNIDMPEGSWYCNDCRAGKKPHYKEVVWVKVGRYRWWPAEVSNPKDIPENILRMKHDVGEFPVLFFGSNDYLWTYQARVFPYMEGDANSKEKMGKGVDSTYKKALDEAALRFKELQAEKELRQLQEDRRNDKKPPPYKQIKVNKPFGKVLIISADLSEIPRCNCKATD-ENPCGMDSECINRMLLYECHPQVCPAGERCQNQCFIKRQYCQVETFRTLSRGWGLRCVHDIKKGGFISEYVGEVIDEEECRARIKHAQENNIGNFYMLTLDKDRIIDAGPKGNEARFMNHCCQPNCETQKWTVNGDTRVGLFSLTDIPAGTELTFNYNLECLGNGKTVCKCGASNCSGFLGVRPKNNPPSDDKGRKLKKKRKSQQEVI---------KEREDECFSCGDGGQIVS---CKRPGCPKVYHADCLNL--TKRPAGRWECPWHQCDLCGQEAASFCEMCPSSYC 1731
BLAST of NSD-1 vs. Ensembl Zebrafish
Match: nsd2 (nuclear receptor binding SET domain protein 2 [Source:ZFIN;Acc:ZDB-GENE-030131-2581]) HSP 1 Score: 376.326 bits (965), Expect = 3.898e-111 Identity = 237/698 (33.95%), Postives = 339/698 (48.57%), Query Frame = 3
Query: 693 CRYCLET-KNIVQCNKCLFNNFHVKCLEFLQNSIETKINDLDRCLECSLGIIRCYACYKIVDISNEQGFMRCIIKTCTKWFHTNCLETGPMLEMTKFPKPGQLVCPCHICHKCELVNPSP-KYRCTKLIVCIMCPATFHTGDWCIPAGSVELNTGEIICPRHLVDLNFSMNIMVPPFVARVKSDLQERIYGNTLTKISEPMTITPSTVTKPTNVNWCFKCGEGGELLCCETCPAAYHFKCTDLKEIPQKFYCPDCASFCYRSYGEIVWIKCGTHPWWPGQILHLENVPKNIAAKKHANGQFVVQFFGSRDYMWRDHGNVFLYEKEDECNSKTSKYRYNNIFLEGIKEAAIGYVTREEKWQSGSCDHVMNSKI--YNKIQVNK--CPLELRRKVVPETPHCNCISFDPKSDCSIGSGCFNVASKCECDPQICNLGDKCKNQNFVKRIYPKQYTFWANDRGWGLKADEFIKTKQFVNEYIGEIITMEESEKRILWANENNITDFYFMELDNGRLIDARQFSNLSRFINNSCDPNLVAEKWIVNREHRIGLFALRDIQKGEELTFQYNLQNKSSNRIVCKCFSVNCSGFLGEAPKMAXXXXXXXXXXXXXXXXXXXXXXXCKSFLTDKNSNSQCFRCGEIIDMLSSIVCSVGPCMKTYHSVCLNLNMANYVQSSWICPHHYCDVCARPSHHFSSNTTESYC 2768
C C +T ++IV C + +H+ C+ ++ S E + C CS G+ C+ C K +E RC C +++H C+ + +T F G CP H C C + K K++ C+ CP +H GD C+ AGS +++ I+C H R K + NV+WCF C +GG LLCCE+CPAA+H C ++ ++C DC S Y +++W+K G + WWP +I H +N+P NI +H G+F V FFGS+DY W G VF Y + D SK + +F + +A + E + ++ H N K + I+VNK +++ + E P CNC + CS S C N EC PQ+C G++C+NQ+F KR+YP+ +GWGL + IK +FVNEY+GE+I EE RI A EN+IT FY + +D R+IDA N SRF+N+SC PN +KW VN + R+GLFA+ DI G ELTF YNL + + VC+C + NCSGFLG+ PK S+ K+ KK K S +CFRCG D ++C C K YH CL+ + W CP H+CDVC + S F S+C
Sbjct: 762 CLVCEQTGEDIVTCAGQCYGTYHLHCI-GVERSAEKIL-----CTACSTGVHVCFTCKK-----SEGEVRRCCALHCGRFYHEACVR---LSALTVFENRG-FRCPLHTCLSCHYSGRAACKATKGKMMRCLRCPVAYHVGDLCVAAGSEMISSSAIVCTNHF----------------RAKKGYSHHSH---------------------VNVSWCFICSKGGRLLCCESCPAAFHPDCLNIAMPDGSWFCNDCRSGKKPKYRDVIWVKLGNYRWWPAEIRHPKNIPTNIQHLRHEIGEFPVFFFGSKDYFWTHQGRVFPYMEGDR-GSKYQQTGIGKVFKNALLDAETRFKEIEMEREAKEA-HENNKKPPPFKYIKVNKPCGRVQVYTADISEIPKCNCKPSTERP-CSFESECLNRMLLYECHPQVCPAGERCQNQDFTKRLYPETKIIRTAGKGWGLISLRDIKKGEFVNEYVGELIDEEECRSRIRHAQENDITHFYMLTIDKDRIIDAGPKGNYSRFMNHSCQPNCETQKWTVNGDTRVGLFAVCDIPAGTELTFNYNLDCLGNEKTVCRCGAPNCSGFLGDRPKNGHTSEPKAKLQKKKPKRKRARNE-------GKKSEDECFRCG---DGGQLVLCDKKGCTKAYHLSCLDRTKRPF--GRWDCPWHHCDVCGKNSAAFCQLCPNSFC 1392
BLAST of NSD-1 vs. Ensembl Xenopus
Match: NSD2 (nuclear receptor binding SET domain protein 2 [Source:NCBI gene;Acc:100125213]) HSP 1 Score: 391.734 bits (1005), Expect = 2.386e-117 Identity = 241/707 (34.09%), Postives = 337/707 (47.67%), Query Frame = 3
Query: 693 CRYCLETKNIVQCNKCLFNNFHVKCLEFLQNSIETKINDLDRCLECSLGIIRCYACYKIVDISNEQGFMRCIIKTCTKWFHTNCLETGPMLEMTKFPKPGQLVCPCHICHKCELVNPS-PKYRCTKLIVCIMCPATFHTGDWCIPAGSVELNTGEIICPRHLVDLNFSMNIMVPPFVARVKSDLQERIYGNTLTKISEPMTITPSTVTKPTNVNWCFKCGEGGELLCCETCPAAYHFKCTDLKEIPQKFYCPDCASFCYRSYGEIVWIKCGTHPWWPGQILHLENVPKNIAAKKHANGQFVVQFFGSRDYMWRDHGNVFLYEKEDECNSKTSKYRYNNIFLEGIKEAAIGY----------VTREEKWQSGSCDHVMNSKIYNKIQVNKCPLELRRKVVPETPHCNCISFDPKSDCSIGSGCFNVASKCECDPQICNLGDKCKNQNFVKRIYPKQYTFWANDRGWGLKADEFIKTKQFVNEYIGEIITMEESEKRILWANENNITDFYFMELDNGRLIDARQFSNLSRFINNSCDPNLVAEKWIVNREHRIGLFALRDIQKGEELTFQYNLQNKSSNRIVCKCFSVNCSGFLGEAPKMAXXXXXXXXXXXXXXXXXXXXXXXCKSFLTDKNSNSQCFRCGEIIDMLSSIVCSVGPCMKTYHSVCLNLNMANYVQSSWICPHHYCDVCARPSHHFSSNTTESYCNKDF 2780
C+ C + +++ C + FH+ C+ + T+ C EC+ G C+ C + + + RCI+ C K++H +CL P+ F G CP H C C NPS P+ K++ C+ CP +H + CI AG L + IIC H F A I NV+WCF C GG LLCCE+CPAA+H C +++ ++C DC + +I+W+K G + WWP ++ H +NVP NI KHA G+F V FFGS+DY W VF Y + D + +F ++EA + VT+E + + H+ +K Y K+QV + E P CNC K C S C N EC PQ+C GD+C+NQ F KR YP+ +GWGL A IK +FVNEYIGE+I EE RI A EN+IT FY + +D R+IDA N SRF+N+SC PN +KW VN + R+GLFA+RDI GEELTF YNL + + +C+C + NCSGFLG+ PK++ + K KK + K S CFRC + ++ ++C C K YH CL+L + W CP H+CDVC + S S S+C +
Sbjct: 620 CQVCEKVGDLMLCEGVCCSAFHLSCI-----GLSTRPAGKYLCKECTSGARSCFLCKE-----SNRDVKRCIVPHCGKFYHESCLRKYPL---AVFESRG-FRCPLHRCATCYFSNPSNPRASKGKMVRCVRCPLAYHGAESCIVAGCTALTSTSIICSSH--------------FAANKAKSHHAHI-----------------------NVSWCFVCSNGGSLLCCESCPAAFHPDCLNIEMPDGSWFCNDCRLGKKPRFNDIIWVKLGNYRWWPAEVCHPKNVPPNIQKMKHAIGEFPVFFFGSKDYYWTHQARVFPYMEGDRGSKHHGGKSIGKVFKNALQEAETRFCEIMRQREAKVTQENEKKPPPYKHIKVNKPYGKVQVYTADIS-------EIPKCNCKPSSEKP-CGFDSECLNRMLMYECHPQVCPAGDRCQNQCFNKRQYPETKIIKTEGKGWGLIATRDIKKGEFVNEYIGELIDEEECMYRIRHAQENDITHFYMLTIDKDRIIDAGPKGNFSRFMNHSCQPNCETQKWSVNGDTRVGLFAVRDIPAGEELTFNYNLDCLGNEKTICRCGAPNCSGFLGDRPKVSSSHEEKVKKPKKKQKKRRTKTD------GKKQSEDYCFRCNDGGEL---VLCDRKFCTKAYHLSCLSLTKRPF--GKWECPWHHCDVCGKASVSCCSLCPNSFCKGHY 1256
BLAST of NSD-1 vs. Ensembl Xenopus
Match: NSD1 (nuclear receptor binding SET domain protein 1 [Source:NCBI gene;Acc:100145675]) HSP 1 Score: 392.889 bits (1008), Expect = 2.725e-117 Identity = 240/714 (33.61%), Postives = 342/714 (47.90%), Query Frame = 3
Query: 696 RYCLETKNIVQCNKCLFNNFHVKCLEFLQNSIETKINDLDRCLECSLGIIRCYACYKIVDISNEQGFMRCIIKTCTKWFHTNC-LETGPMLEMTKFPKPGQLVCPCHICHKCELVNPS-PKYRCTKLIVCIMCPATFHTGDWCIPAGSVELNTGEIICPRHLVDLNFSMNIMVPPFVARVKSDLQERIYGNTLTKISEPMTITPSTVTKPTNVNWCFKCGEGGELLCCETCPAAYHFKCTDLKEIPQKFYCPDCASFCYRSYGEIVWIKCGTHPWWPGQILHLENVPKNIAAKKHANGQFVVQFFGSRDYMWRDHGNVFLYEKEDECNSKTSKYRYNNIFLEGIKEAAIGY----VTREEKWQSGSCDHVMNSKIYNKIQVNK--CPLELRRKVVPETPHCNCISFDPKSDCSIGSGCFNVASKCECDPQICNLGDKCKNQNFVKRIYPKQYTFWANDRGWGLKADEFIKTKQFVNEYIGEIITMEESEKRILWANENNITDFYFMELDNGRLIDARQFSNLSRFINNSCDPNLVAEKWIVNREHRIGLFALRDIQKGEELTFQYNLQNKSSNRIVCKCFSVNCSGFLGEAPKMAXXXXXXXXXXXXXXXXXXXXXXXCKSFLTDKNSNSQCFRCGEIIDMLSSIVCSVGPCMKTYHSVCLNLNMANYVQSSWICPHHYCDVCARPSHHFSSNTTESYCNKD-----FIKKFNS 2798
+ C + ++ C FH++CL +E C ECS G C+ C + ++QG RC++ C K++H C L+ P + + C HIC C NPS P +L+ C+ CP +H D+C+PAG+V L + IICP H F R E + NV+WCF C EGG LLCCE+CPAA+H +C ++ ++C DC + Y E+VW+K G + WWP ++ H + +P NI KH G+F V FFGS+DY+W VF Y + D N + ++ +G+ EAA + +E + + Y I+VN+ +++ + E P CNC + D ++ C S C N EC P +C G++C+NQ F KR YP+ F RGWGL+ IK +FVNEY+GE+I EE RI +A E +IT+FY + LD R+IDA N +RF+N+ C PN +KW VN + R+GLFAL DI+ G ELTF YNL+ + + VCKC + NCSGFLG PK VS +K K K +CF CG+ ++S C C K YH+ CL L W CP H CD+C + + S+C + FI K +
Sbjct: 665 QVCEKPGELLLCEAQCCGAFHLQCL-----GMEAMPQGKFVCTECSSGYHTCFVCKE-----SDQGVKRCMLPLCGKYYHEECALKYPPATQQNR-----GFRCSLHICSTCYATNPSNPSASKGRLMRCVRCPIAYHANDFCLPAGAVTLASNSIICPNH--------------FTPRRGCKNHEHV-----------------------NVSWCFVCSEGGSLLCCESCPAAFHRECLNIDMPEGSWFCNDCKAGKKPHYKEVVWVKVGRYRWWPAEVCHPKTIPPNIQKMKHDIGEFPVVFFGSKDYLWTHQARVFPYMEGDALNKDKMSKGMDAVYKKGLMEAAERFEELKAQKEMRQLQEDKKNDKKPPPYKHIKVNRPVGKVQILTADLSEIPRCNCKATD-ENPCGQDSECINRMLLYECHPSVCPAGERCQNQAFSKRQYPEVEIFRTLSRGWGLRCRTDIKKGEFVNEYVGEMIDEEECRARIRYAQEQDITNFYMLTLDKDRVIDAGPKGNFARFMNHCCQPNCETQKWTVNGDTRVGLFALCDIKAGVELTFNYNLECLGNGKTVCKCGAPNCSGFLGVRPKNQPVSSEDKGKKRKQYVKR-------KKSEVVKEHEDECFSCGDGGQLVS---CKKPGCPKVYHAECLKL--TRRPAGKWECPWHQCDICHKEAASLCEMCPSSFCKQHREGMLFISKLDG 1313
BLAST of NSD-1 vs. Ensembl Xenopus
Match: NSD1 (nuclear receptor binding SET domain protein 1 [Source:NCBI gene;Acc:100145675]) HSP 1 Score: 395.971 bits (1016), Expect = 2.808e-117 Identity = 241/714 (33.75%), Postives = 343/714 (48.04%), Query Frame = 3
Query: 693 CRYCLETKNIVQCNKCLFNNFHVKCLEFLQNSIETKINDLDRCLECSLGIIRCYACYKIVDISNEQGFMRCIIKTCTKWFHTNC-LETGPMLEMTKFPKPGQLVCPCHICHKCELVNPS-PKYRCTKLIVCIMCPATFHTGDWCIPAGSVELNTGEIICPRHLVDLNFSMNIMVPPFVARVKSDLQERIYGNTLTKISEPMTITPSTVTKPTNVNWCFKCGEGGELLCCETCPAAYHFKCTDLKEIPQKFYCPDCASFCYRSYGEIVWIKCGTHPWWPGQILHLENVPKNIAAKKHANGQFVVQFFGSRDYMWRDHGNVFLYEKEDECNSKTSKYRYNNIFLEGIKEAAIGY----VTREEKWQSGSCDHVMNSKIYNKIQVNK--CPLELRRKVVPETPHCNCISFDPKSDCSIGSGCFNVASKCECDPQICNLGDKCKNQNFVKRIYPKQYTFWANDRGWGLKADEFIKTKQFVNEYIGEIITMEESEKRILWANENNITDFYFMELDNGRLIDARQFSNLSRFINNSCDPNLVAEKWIVNREHRIGLFALRDIQKGEELTFQYNLQNKSSNRIVCKCFSVNCSGFLGEAPKMAXXXXXXXXXXXXXXXXXXXXXXXCKSFLTDKNSNSQCFRCGEIIDMLSSIVCSVGPCMKTYHSVCLNLNMANYVQSSWICPHHYCDVCARPSHHFSSNTTESYCNKD-----FIKKFN 2795
C+ C + ++ C FH++CL +E C ECS G C+ C + ++QG RC++ C K++H C L+ P + + C HIC C NPS P +L+ C+ CP +H D+C+PAG+V L + IICP H F R E + NV+WCF C EGG LLCCE+CPAA+H +C ++ ++C DC + Y E+VW+K G + WWP ++ H + +P NI KH G+F V FFGS+DY+W VF Y + D N + ++ +G+ EAA + +E + + Y I+VN+ +++ + E P CNC + D ++ C S C N EC P +C G++C+NQ F KR YP+ F RGWGL+ IK +FVNEY+GE+I EE RI +A E +IT+FY + LD R+IDA N +RF+N+ C PN +KW VN + R+GLFAL DI+ G ELTF YNL+ + + VCKC + NCSGFLG PK VS +K K K +CF CG+ ++S C C K YH+ CL L W CP H CD+C + + S+C + FI K +
Sbjct: 549 CQVCEKPGELLLCEAQCCGAFHLQCL-----GMEAMPQGKFVCTECSSGYHTCFVCKE-----SDQGVKRCMLPLCGKYYHEECALKYPPATQQNRG-----FRCSLHICSTCYATNPSNPSASKGRLMRCVRCPIAYHANDFCLPAGAVTLASNSIICPNH--------------FTPRRGCKNHEHV-----------------------NVSWCFVCSEGGSLLCCESCPAAFHRECLNIDMPEGSWFCNDCKAGKKPHYKEVVWVKVGRYRWWPAEVCHPKTIPPNIQKMKHDIGEFPVVFFGSKDYLWTHQARVFPYMEGDALNKDKMSKGMDAVYKKGLMEAAERFEELKAQKEMRQLQEDKKNDKKPPPYKHIKVNRPVGKVQILTADLSEIPRCNCKATD-ENPCGQDSECINRMLLYECHPSVCPAGERCQNQAFSKRQYPEVEIFRTLSRGWGLRCRTDIKKGEFVNEYVGEMIDEEECRARIRYAQEQDITNFYMLTLDKDRVIDAGPKGNFARFMNHCCQPNCETQKWTVNGDTRVGLFALCDIKAGVELTFNYNLECLGNGKTVCKCGAPNCSGFLGVRPKNQPVSSEDKGKKRKQYVKR-------KKSEVVKEHEDECFSCGDGGQLVS---CKKPGCPKVYHAECLKL--TRRPAGKWECPWHQCDICHKEAASLCEMCPSSFCKQHREGMLFISKLD 1197
BLAST of NSD-1 vs. Ensembl Xenopus
Match: NSD2 (nuclear receptor binding SET domain protein 2 [Source:NCBI gene;Acc:100125213]) HSP 1 Score: 388.652 bits (997), Expect = 1.175e-116 Identity = 241/707 (34.09%), Postives = 337/707 (47.67%), Query Frame = 3
Query: 693 CRYCLETKNIVQCNKCLFNNFHVKCLEFLQNSIETKINDLDRCLECSLGIIRCYACYKIVDISNEQGFMRCIIKTCTKWFHTNCLETGPMLEMTKFPKPGQLVCPCHICHKCELVNPS-PKYRCTKLIVCIMCPATFHTGDWCIPAGSVELNTGEIICPRHLVDLNFSMNIMVPPFVARVKSDLQERIYGNTLTKISEPMTITPSTVTKPTNVNWCFKCGEGGELLCCETCPAAYHFKCTDLKEIPQKFYCPDCASFCYRSYGEIVWIKCGTHPWWPGQILHLENVPKNIAAKKHANGQFVVQFFGSRDYMWRDHGNVFLYEKEDECNSKTSKYRYNNIFLEGIKEAAIGY----------VTREEKWQSGSCDHVMNSKIYNKIQVNKCPLELRRKVVPETPHCNCISFDPKSDCSIGSGCFNVASKCECDPQICNLGDKCKNQNFVKRIYPKQYTFWANDRGWGLKADEFIKTKQFVNEYIGEIITMEESEKRILWANENNITDFYFMELDNGRLIDARQFSNLSRFINNSCDPNLVAEKWIVNREHRIGLFALRDIQKGEELTFQYNLQNKSSNRIVCKCFSVNCSGFLGEAPKMAXXXXXXXXXXXXXXXXXXXXXXXCKSFLTDKNSNSQCFRCGEIIDMLSSIVCSVGPCMKTYHSVCLNLNMANYVQSSWICPHHYCDVCARPSHHFSSNTTESYCNKDF 2780
C+ C + +++ C + FH+ C+ + T+ C EC+ G C+ C + + + RCI+ C K++H +CL P+ F G CP H C C NPS P+ K++ C+ CP +H + CI AG L + IIC H F A I NV+WCF C GG LLCCE+CPAA+H C +++ ++C DC + +I+W+K G + WWP ++ H +NVP NI KHA G+F V FFGS+DY W VF Y + D + +F ++EA + VT+E + + H+ +K Y K+QV + E P CNC K C S C N EC PQ+C GD+C+NQ F KR YP+ +GWGL A IK +FVNEYIGE+I EE RI A EN+IT FY + +D R+IDA N SRF+N+SC PN +KW VN + R+GLFA+RDI GEELTF YNL + + +C+C + NCSGFLG+ PK + S +K K + + K S CFRC + ++ ++C C K YH CL+L + W CP H+CDVC + S S S+C +
Sbjct: 557 CQVCEKVGDLMLCEGVCCSAFHLSCI-----GLSTRPAGKYLCKECTSGARSCFLCKE-----SNRDVKRCIVPHCGKFYHESCLRKYPL---AVFESRG-FRCPLHRCATCYFSNPSNPRASKGKMVRCVRCPLAYHGAESCIVAGCTALTSTSIICSSH--------------FAANKAKSHHAHI-----------------------NVSWCFVCSNGGSLLCCESCPAAFHPDCLNIEMPDGSWFCNDCRLGKKPRFNDIIWVKLGNYRWWPAEVCHPKNVPPNIQKMKHAIGEFPVFFFGSKDYYWTHQARVFPYMEGDRGSKHHGGKSIGKVFKNALQEAETRFCEIMRQREAKVTQENEKKPPPYKHIKVNKPYGKVQVYTADIS-------EIPKCNCKPSSEKP-CGFDSECLNRMLMYECHPQVCPAGDRCQNQCFNKRQYPETKIIKTEGKGWGLIATRDIKKGEFVNEYIGELIDEEECMYRIRHAQENDITHFYMLTIDKDRIIDAGPKGNFSRFMNHSCQPNCETQKWSVNGDTRVGLFAVRDIPAGEELTFNYNLDCLGNEKTICRCGAPNCSGFLGDRPK----NNTASSHEEKVKKPKKKQKKRRTKTDGKKQSEDYCFRCNDGGEL---VLCDRKFCTKAYHLSCLSLTKRPF--GKWECPWHHCDVCGKASVSCCSLCPNSFCKGHY 1195
BLAST of NSD-1 vs. Ensembl Xenopus
Match: NSD1 (nuclear receptor binding SET domain protein 1 [Source:NCBI gene;Acc:100145675]) HSP 1 Score: 395.586 bits (1015), Expect = 1.325e-116 Identity = 241/714 (33.75%), Postives = 343/714 (48.04%), Query Frame = 3
Query: 693 CRYCLETKNIVQCNKCLFNNFHVKCLEFLQNSIETKINDLDRCLECSLGIIRCYACYKIVDISNEQGFMRCIIKTCTKWFHTNC-LETGPMLEMTKFPKPGQLVCPCHICHKCELVNPS-PKYRCTKLIVCIMCPATFHTGDWCIPAGSVELNTGEIICPRHLVDLNFSMNIMVPPFVARVKSDLQERIYGNTLTKISEPMTITPSTVTKPTNVNWCFKCGEGGELLCCETCPAAYHFKCTDLKEIPQKFYCPDCASFCYRSYGEIVWIKCGTHPWWPGQILHLENVPKNIAAKKHANGQFVVQFFGSRDYMWRDHGNVFLYEKEDECNSKTSKYRYNNIFLEGIKEAAIGY----VTREEKWQSGSCDHVMNSKIYNKIQVNK--CPLELRRKVVPETPHCNCISFDPKSDCSIGSGCFNVASKCECDPQICNLGDKCKNQNFVKRIYPKQYTFWANDRGWGLKADEFIKTKQFVNEYIGEIITMEESEKRILWANENNITDFYFMELDNGRLIDARQFSNLSRFINNSCDPNLVAEKWIVNREHRIGLFALRDIQKGEELTFQYNLQNKSSNRIVCKCFSVNCSGFLGEAPKMAXXXXXXXXXXXXXXXXXXXXXXXCKSFLTDKNSNSQCFRCGEIIDMLSSIVCSVGPCMKTYHSVCLNLNMANYVQSSWICPHHYCDVCARPSHHFSSNTTESYCNKD-----FIKKFN 2795
C+ C + ++ C FH++CL +E C ECS G C+ C + ++QG RC++ C K++H C L+ P + + C HIC C NPS P +L+ C+ CP +H D+C+PAG+V L + IICP H F R E + NV+WCF C EGG LLCCE+CPAA+H +C ++ ++C DC + Y E+VW+K G + WWP ++ H + +P NI KH G+F V FFGS+DY+W VF Y + D N + ++ +G+ EAA + +E + + Y I+VN+ +++ + E P CNC + D ++ C S C N EC P +C G++C+NQ F KR YP+ F RGWGL+ IK +FVNEY+GE+I EE RI +A E +IT+FY + LD R+IDA N +RF+N+ C PN +KW VN + R+GLFAL DI+ G ELTF YNL+ + + VCKC + NCSGFLG PK VS +K K K +CF CG+ ++S C C K YH+ CL L W CP H CD+C + + S+C + FI K +
Sbjct: 711 CQVCEKPGELLLCEAQCCGAFHLQCL-----GMEAMPQGKFVCTECSSGYHTCFVCKE-----SDQGVKRCMLPLCGKYYHEECALKYPPATQQNRG-----FRCSLHICSTCYATNPSNPSASKGRLMRCVRCPIAYHANDFCLPAGAVTLASNSIICPNH--------------FTPRRGCKNHEHV-----------------------NVSWCFVCSEGGSLLCCESCPAAFHRECLNIDMPEGSWFCNDCKAGKKPHYKEVVWVKVGRYRWWPAEVCHPKTIPPNIQKMKHDIGEFPVVFFGSKDYLWTHQARVFPYMEGDALNKDKMSKGMDAVYKKGLMEAAERFEELKAQKEMRQLQEDKKNDKKPPPYKHIKVNRPVGKVQILTADLSEIPRCNCKATD-ENPCGQDSECINRMLLYECHPSVCPAGERCQNQAFSKRQYPEVEIFRTLSRGWGLRCRTDIKKGEFVNEYVGEMIDEEECRARIRYAQEQDITNFYMLTLDKDRVIDAGPKGNFARFMNHCCQPNCETQKWTVNGDTRVGLFALCDIKAGVELTFNYNLECLGNGKTVCKCGAPNCSGFLGVRPKNQPVSSEDKGKKRKQYVKR-------KKSEVVKEHEDECFSCGDGGQLVS---CKKPGCPKVYHAECLKL--TRRPAGKWECPWHQCDICHKEAASLCEMCPSSFCKQHREGMLFISKLD 1359
BLAST of NSD-1 vs. Ensembl Mouse
Match: Nsd2 (nuclear receptor binding SET domain protein 2 [Source:MGI Symbol;Acc:MGI:1276574]) HSP 1 Score: 393.66 bits (1010), Expect = 1.027e-117 Identity = 244/735 (33.20%), Postives = 348/735 (47.35%), Query Frame = 3
Query: 627 PIKYAFDELTLPFVSVKLTNKN--------CRYCLETKNIVQCNKCLFNNFHVKCLEFLQNSIETKINDLDRCLECSLGIIRCYACYKIVDISNEQGFMRCIIKTCTKWFHTNCLETGPMLEMTKFPKPGQLVCPCHICHKCELVNPS-PKYRCTKLIVCIMCPATFHTGDWCIPAGSVELNTGEIICPRHLVDLNFSMNIMVPPFVARVKSDLQERIYGNTLTKISEPMTITPSTVTKPTNVNWCFKCGEGGELLCCETCPAAYHFKCTDLKEIPQKFYCPDCASFCYRSYGEIVWIKCGTHPWWPGQILHLENVPKNIAAKKHANGQFVVQFFGSRDYMWRDHGNVFLYEKEDECNSKTSKYRYNNIFLEGIKEAAIGY----------VTREEKWQSGSCDHVMNSKIYNKIQVNKCPLELRRKVVPETPHCNCISFDPKSDCSIGSGCFNVASKCECDPQICNLGDKCKNQNFVKRIYPKQYTFWANDRGWGLKADEFIKTKQFVNEYIGEIITMEESEKRILWANENNITDFYFMELDNGRLIDARQFSNLSRFINNSCDPNLVAEKWIVNREHRIGLFALRDIQKGEELTFQYNLQNKSSNRIVCKCFSVNCSGFLGEAPKMAXXXXXXXXXXXXXXXXXXXXXXXCKSFLTDKNSNSQCFRCGEIIDMLSSIVCSVGPCMKTYHSVCLNLNMANYVQSSWICPHHYCDVCARPSHHFSSNTTESYCNK 2774
P + A + T VS K + + C+ C +T +++ C FH+ CL L E + C EC+ GI C+ C + ++ RC++ C K++H C++ P+ T F G CP H C C NPS P+ K++ C+ CP +H GD C+ AG + + IIC H F AR + NV+WCF C +GG LLCCE CPAA+H C +++ ++C DC + + +I+W+K G + WWP ++ H +NVP NI KH G+F V FFGS+DY W VF Y + D + +F ++EA + T+E + + H+ +K Y K+Q+ + E P CNC D ++ C S C N EC PQ+C G+ C+NQ F KR YP+ + +GWGL A I+ +FVNEY+GE+I EE RI +A+EN+IT FY + +D R+IDA N SRF+N+SC PN KW VN + R+GLFA+ DI G ELTF YNL + + VC+C + NCSGFLG+ PK + + K K + S +CFRCG D ++C C K YH CL L + W CP H+CDVC +PS F S+C +
Sbjct: 641 PYESADETQTEASVSSKKSERGMAAKKEYVCQLCEKTGSLLLCEGPCCGAFHLACL-GLSRRPEGRFT----CTECASGIHSCFVCKE-----SKMEVKRCVVNQCGKFYHEACVKKYPL---TVFESRG-FRCPLHSCMSCHASNPSNPRPSKGKMMRCVRCPVAYHGGDACLAAGCSVIASNSIICTGH--------------FTARKGKRHHTHV-----------------------NVSWCFVCSKGGSLLCCEACPAAFHPDCLNIEMPDGSWFCNDCRAGKKLHFQDIIWVKLGNYRWWPAEVCHPKNVPPNIQKMKHEIGEFPVFFFGSKDYYWTHQARVFPYMEGDRGSRYQGVRGIGRVFKNALQEAEARFNEVKLQREARETQESERKPPPYKHIKVNKPYGKVQIYTAD-------ISEIPKCNCKPTD-ENPCGSDSECLNRMLMFECHPQVCPAGEYCQNQCFTKRQYPETKIIKTDGKGWGLVAKRDIRKGEFVNEYVGELIDEEECMARIKYAHENDITHFYMLTIDKDRIIDAGPKGNYSRFMNHSCQPNCETLKWTVNGDTRVGLFAVCDIPAGTELTFNYNLDCLGNEKTVCRCGASNCSGFLGDRPKTSASLSSEEKGKKAKKKTRRRR----AKGEGKRQSEDECFRCG---DGGQLVLCDRKFCTKAYHLSCLGLGKRPF--GKWECPWHHCDVCGKPSTSFCHLCPNSFCKE 1307
BLAST of NSD-1 vs. Ensembl Mouse
Match: Nsd2 (nuclear receptor binding SET domain protein 2 [Source:MGI Symbol;Acc:MGI:1276574]) HSP 1 Score: 393.66 bits (1010), Expect = 1.027e-117 Identity = 244/735 (33.20%), Postives = 348/735 (47.35%), Query Frame = 3
Query: 627 PIKYAFDELTLPFVSVKLTNKN--------CRYCLETKNIVQCNKCLFNNFHVKCLEFLQNSIETKINDLDRCLECSLGIIRCYACYKIVDISNEQGFMRCIIKTCTKWFHTNCLETGPMLEMTKFPKPGQLVCPCHICHKCELVNPS-PKYRCTKLIVCIMCPATFHTGDWCIPAGSVELNTGEIICPRHLVDLNFSMNIMVPPFVARVKSDLQERIYGNTLTKISEPMTITPSTVTKPTNVNWCFKCGEGGELLCCETCPAAYHFKCTDLKEIPQKFYCPDCASFCYRSYGEIVWIKCGTHPWWPGQILHLENVPKNIAAKKHANGQFVVQFFGSRDYMWRDHGNVFLYEKEDECNSKTSKYRYNNIFLEGIKEAAIGY----------VTREEKWQSGSCDHVMNSKIYNKIQVNKCPLELRRKVVPETPHCNCISFDPKSDCSIGSGCFNVASKCECDPQICNLGDKCKNQNFVKRIYPKQYTFWANDRGWGLKADEFIKTKQFVNEYIGEIITMEESEKRILWANENNITDFYFMELDNGRLIDARQFSNLSRFINNSCDPNLVAEKWIVNREHRIGLFALRDIQKGEELTFQYNLQNKSSNRIVCKCFSVNCSGFLGEAPKMAXXXXXXXXXXXXXXXXXXXXXXXCKSFLTDKNSNSQCFRCGEIIDMLSSIVCSVGPCMKTYHSVCLNLNMANYVQSSWICPHHYCDVCARPSHHFSSNTTESYCNK 2774
P + A + T VS K + + C+ C +T +++ C FH+ CL L E + C EC+ GI C+ C + ++ RC++ C K++H C++ P+ T F G CP H C C NPS P+ K++ C+ CP +H GD C+ AG + + IIC H F AR + NV+WCF C +GG LLCCE CPAA+H C +++ ++C DC + + +I+W+K G + WWP ++ H +NVP NI KH G+F V FFGS+DY W VF Y + D + +F ++EA + T+E + + H+ +K Y K+Q+ + E P CNC D ++ C S C N EC PQ+C G+ C+NQ F KR YP+ + +GWGL A I+ +FVNEY+GE+I EE RI +A+EN+IT FY + +D R+IDA N SRF+N+SC PN KW VN + R+GLFA+ DI G ELTF YNL + + VC+C + NCSGFLG+ PK + + K K + S +CFRCG D ++C C K YH CL L + W CP H+CDVC +PS F S+C +
Sbjct: 641 PYESADETQTEASVSSKKSERGMAAKKEYVCQLCEKTGSLLLCEGPCCGAFHLACL-GLSRRPEGRFT----CTECASGIHSCFVCKE-----SKMEVKRCVVNQCGKFYHEACVKKYPL---TVFESRG-FRCPLHSCMSCHASNPSNPRPSKGKMMRCVRCPVAYHGGDACLAAGCSVIASNSIICTGH--------------FTARKGKRHHTHV-----------------------NVSWCFVCSKGGSLLCCEACPAAFHPDCLNIEMPDGSWFCNDCRAGKKLHFQDIIWVKLGNYRWWPAEVCHPKNVPPNIQKMKHEIGEFPVFFFGSKDYYWTHQARVFPYMEGDRGSRYQGVRGIGRVFKNALQEAEARFNEVKLQREARETQESERKPPPYKHIKVNKPYGKVQIYTAD-------ISEIPKCNCKPTD-ENPCGSDSECLNRMLMFECHPQVCPAGEYCQNQCFTKRQYPETKIIKTDGKGWGLVAKRDIRKGEFVNEYVGELIDEEECMARIKYAHENDITHFYMLTIDKDRIIDAGPKGNYSRFMNHSCQPNCETLKWTVNGDTRVGLFAVCDIPAGTELTFNYNLDCLGNEKTVCRCGASNCSGFLGDRPKTSASLSSEEKGKKAKKKTRRRR----AKGEGKRQSEDECFRCG---DGGQLVLCDRKFCTKAYHLSCLGLGKRPF--GKWECPWHHCDVCGKPSTSFCHLCPNSFCKE 1307
BLAST of NSD-1 vs. Ensembl Mouse
Match: Nsd2 (nuclear receptor binding SET domain protein 2 [Source:MGI Symbol;Acc:MGI:1276574]) HSP 1 Score: 393.66 bits (1010), Expect = 1.066e-117 Identity = 243/735 (33.06%), Postives = 349/735 (47.48%), Query Frame = 3
Query: 627 PIKYAFDELTLPFVSVKLTNKN--------CRYCLETKNIVQCNKCLFNNFHVKCLEFLQNSIETKINDLDRCLECSLGIIRCYACYKIVDISNEQGFMRCIIKTCTKWFHTNCLETGPMLEMTKFPKPGQLVCPCHICHKCELVNPS-PKYRCTKLIVCIMCPATFHTGDWCIPAGSVELNTGEIICPRHLVDLNFSMNIMVPPFVARVKSDLQERIYGNTLTKISEPMTITPSTVTKPTNVNWCFKCGEGGELLCCETCPAAYHFKCTDLKEIPQKFYCPDCASFCYRSYGEIVWIKCGTHPWWPGQILHLENVPKNIAAKKHANGQFVVQFFGSRDYMWRDHGNVFLYEKEDECNSKTSKYRYNNIFLEGIKEAAIGY----------VTREEKWQSGSCDHVMNSKIYNKIQVNKCPLELRRKVVPETPHCNCISFDPKSDCSIGSGCFNVASKCECDPQICNLGDKCKNQNFVKRIYPKQYTFWANDRGWGLKADEFIKTKQFVNEYIGEIITMEESEKRILWANENNITDFYFMELDNGRLIDARQFSNLSRFINNSCDPNLVAEKWIVNREHRIGLFALRDIQKGEELTFQYNLQNKSSNRIVCKCFSVNCSGFLGEAPKMAXXXXXXXXXXXXXXXXXXXXXXXCKSFLTDKNSNSQCFRCGEIIDMLSSIVCSVGPCMKTYHSVCLNLNMANYVQSSWICPHHYCDVCARPSHHFSSNTTESYCNK 2774
P + A + T VS K + + C+ C +T +++ C FH+ CL L E + C EC+ GI C+ C + ++ RC++ C K++H C++ P+ T F G CP H C C NPS P+ K++ C+ CP +H GD C+ AG + + IIC H F AR + NV+WCF C +GG LLCCE CPAA+H C +++ ++C DC + + +I+W+K G + WWP ++ H +NVP NI KH G+F V FFGS+DY W VF Y + D + +F ++EA + T+E + + H+ +K Y K+Q+ + E P CNC D ++ C S C N EC PQ+C G+ C+NQ F KR YP+ + +GWGL A I+ +FVNEY+GE+I EE RI +A+EN+IT FY + +D R+IDA N SRF+N+SC PN KW VN + R+GLFA+ DI G ELTF YNL + + VC+C + NCSGFLG+ PK + + K K + S +CFRCG+ + ++C C K YH CL L + W CP H+CDVC +PS F S+C +
Sbjct: 640 PYESADETQTEASVSSKKSERGMAAKKEYVCQLCEKTGSLLLCEGPCCGAFHLACL-GLSRRPEGRFT----CTECASGIHSCFVCKE-----SKMEVKRCVVNQCGKFYHEACVKKYPL---TVFESRG-FRCPLHSCMSCHASNPSNPRPSKGKMMRCVRCPVAYHGGDACLAAGCSVIASNSIICTGH--------------FTARKGKRHHTHV-----------------------NVSWCFVCSKGGSLLCCEACPAAFHPDCLNIEMPDGSWFCNDCRAGKKLHFQDIIWVKLGNYRWWPAEVCHPKNVPPNIQKMKHEIGEFPVFFFGSKDYYWTHQARVFPYMEGDRGSRYQGVRGIGRVFKNALQEAEARFNEVKLQREARETQESERKPPPYKHIKVNKPYGKVQIYTAD-------ISEIPKCNCKPTD-ENPCGSDSECLNRMLMFECHPQVCPAGEYCQNQCFTKRQYPETKIIKTDGKGWGLVAKRDIRKGEFVNEYVGELIDEEECMARIKYAHENDITHFYMLTIDKDRIIDAGPKGNYSRFMNHSCQPNCETLKWTVNGDTRVGLFAVCDIPAGTELTFNYNLDCLGNEKTVCRCGASNCSGFLGDRPKTSASLSSEEKGKKAKKKTRRRR----AKGEGKRQSEDECFRCGDGGQL---VLCDRKFCTKAYHLSCLGLGKRPF--GKWECPWHHCDVCGKPSTSFCHLCPNSFCKE 1306
BLAST of NSD-1 vs. Ensembl Mouse
Match: Nsd1 (nuclear receptor-binding SET-domain protein 1 [Source:MGI Symbol;Acc:MGI:1276545]) HSP 1 Score: 382.104 bits (980), Expect = 1.293e-111 Identity = 246/745 (33.02%), Postives = 361/745 (48.46%), Query Frame = 3
Query: 606 QEIIKREPIKYAFDELTLPFVSVKLTNKN-CRYCLETKNIVQCNKCLFNNFHVKCLEFLQNSIETKINDLDRCLECSLGIIRCYACYKIVDISNEQGFMRCIIKTCTKWFHTNCLET-GPMLEMTKFPKPGQLVCPCHICHKCELVNPSP-KYRCTKLIVCIMCPATFHTGDWCIPAGSVELNTGEIICPRHLVDLNFSMNIMVPPFVARVKSDLQERIYGNTLTKISEPMTITPSTVTKPTNVNWCFKCGEGGELLCCETCPAAYHFKCTDLKEIPQ-KFYCPDCASFCYRSYGEIVWIKCGTHPWWPGQILHLENVPKNIAAKKHANGQFVVQFFGSRDYMWRDHGNVFLYEKEDECNSKTSKYRYNNIFLEGIKEAAIGY--VTREEKWQSGSCDHVMNSKI--YNKIQVNK--CPLELRRKVVPETPHCNCISFDPKSDCSIGSGCFNVASKCECDPQICNLGDKCKNQNFVKRIYPKQYTFWANDRGWGLKADEFIKTKQFVNEYIGEIITMEESEKRILWANENNITDFYFMELDNGRLIDARQFSNLSRFINNSCDPNLVAEKWIVNREHRIGLFALRDIQKGEELTFQYNLQNKSSNRIVCKCFSVNCSGFLGEAPKMAXXXXXXXXXXXXXXXXXXXXXXXCKSFLTDKNSNSQCFRCGEIIDMLSSIVCSVGPCMKTYHSVCLNLNMANYVQSSWICPHHYCDVCARPSHHFSSNTTESYCNKD-----FIKKFN 2795
+E ++ +P A +L + +N C+ C + ++ C FH++CL + I C EC GI C+ C + + + RC++ C K++H C++ P + K CP HIC C NP+ +L+ C+ CP +H D+C+ AGS L + IICP H F R E + NV+WCF C EGG LLCC++CPAA+H +C ++ +IP+ +YC DC + Y EIVW+K G + WWP +I H VP NI +H G+F V FFGS DY+W VF Y + D + + + + ++EAA + + +++ + D + K Y I+VN+ +++ + E P CNC + D ++ C I S C N EC P +C G +C+NQ F KR YP F RGWGL+ IK +FVNEY+GE+I EE RI +A E++IT+FY + LD R+IDA N +RF+N+ C PN +KW VN + R+GLFAL DI+ G ELTF YNL+ + + VCKC + NCSGFLG PK + ++ + + + +T K +CF CG+ ++S C C K YH+ CLNL W CP H CDVC + + F S+C + FI K +
Sbjct: 1517 EEGVEHDPGMSASKKLQVERGGGAALKENVCQNCEKLGELLLCEAQCCGAFHLECLGLPEMPRGKFI-----CNECHTGIHTCFVCKQ-----SGEDVKRCLLPLCGKFYHEECVQKYPPTVTQNKG-----FRCPLHICITCHAANPANVSASKGRLMRCVRCPVAYHANDFCLAAGSKILASNSIICPNH--------------FTPRRGCRNHEHV-----------------------NVSWCFVCSEGGSLLCCDSCPAAFHRECLNI-DIPEGNWYCNDCKAGKKPHYREIVWVKVGRYRWWPAEICHPRAVPSNIDKMRHDVGEFPVLFFGSNDYLWTHQARVFPYMEGDVSSKDKMGKGVDGTYKKALQEAAARFEELKAQKELRQLQEDRKNDKKPPPYKHIKVNRPIGRVQIFTADLSEIPRCNCKATD-ENPCGIDSECINRMLLYECHPTVCPAGVRCQNQCFSKRQYPDVEIFRTLQRGWGLRTKTDIKKGEFVNEYVGELIDEEECRARIRYAQEHDITNFYMLTLDKDRIIDAGPKGNYARFMNHCCQPNCETQKWSVNGDTRVGLFALSDIKAGTELTFNYNLECLGNGKTVCKCGAPNCSGFLGVRPK---NQPIVTEEKSRKFKRKPHGKRRSQGEVT-KEREDECFSCGDAGQLVS---CKKPGCPKVYHADCLNLT--KRPAGKWECPWHQCDVCGKEAASFCEMCPSSFCKQHREGMLFISKLD 2198
BLAST of NSD-1 vs. Ensembl Mouse
Match: Nsd1 (nuclear receptor-binding SET-domain protein 1 [Source:MGI Symbol;Acc:MGI:1276545]) HSP 1 Score: 382.104 bits (980), Expect = 1.366e-111 Identity = 246/745 (33.02%), Postives = 361/745 (48.46%), Query Frame = 3
Query: 606 QEIIKREPIKYAFDELTLPFVSVKLTNKN-CRYCLETKNIVQCNKCLFNNFHVKCLEFLQNSIETKINDLDRCLECSLGIIRCYACYKIVDISNEQGFMRCIIKTCTKWFHTNCLET-GPMLEMTKFPKPGQLVCPCHICHKCELVNPSP-KYRCTKLIVCIMCPATFHTGDWCIPAGSVELNTGEIICPRHLVDLNFSMNIMVPPFVARVKSDLQERIYGNTLTKISEPMTITPSTVTKPTNVNWCFKCGEGGELLCCETCPAAYHFKCTDLKEIPQ-KFYCPDCASFCYRSYGEIVWIKCGTHPWWPGQILHLENVPKNIAAKKHANGQFVVQFFGSRDYMWRDHGNVFLYEKEDECNSKTSKYRYNNIFLEGIKEAAIGY--VTREEKWQSGSCDHVMNSKI--YNKIQVNK--CPLELRRKVVPETPHCNCISFDPKSDCSIGSGCFNVASKCECDPQICNLGDKCKNQNFVKRIYPKQYTFWANDRGWGLKADEFIKTKQFVNEYIGEIITMEESEKRILWANENNITDFYFMELDNGRLIDARQFSNLSRFINNSCDPNLVAEKWIVNREHRIGLFALRDIQKGEELTFQYNLQNKSSNRIVCKCFSVNCSGFLGEAPKMAXXXXXXXXXXXXXXXXXXXXXXXCKSFLTDKNSNSQCFRCGEIIDMLSSIVCSVGPCMKTYHSVCLNLNMANYVQSSWICPHHYCDVCARPSHHFSSNTTESYCNKD-----FIKKFN 2795
+E ++ +P A +L + +N C+ C + ++ C FH++CL + I C EC GI C+ C + + + RC++ C K++H C++ P + K CP HIC C NP+ +L+ C+ CP +H D+C+ AGS L + IICP H F R E + NV+WCF C EGG LLCC++CPAA+H +C ++ +IP+ +YC DC + Y EIVW+K G + WWP +I H VP NI +H G+F V FFGS DY+W VF Y + D + + + + ++EAA + + +++ + D + K Y I+VN+ +++ + E P CNC + D ++ C I S C N EC P +C G +C+NQ F KR YP F RGWGL+ IK +FVNEY+GE+I EE RI +A E++IT+FY + LD R+IDA N +RF+N+ C PN +KW VN + R+GLFAL DI+ G ELTF YNL+ + + VCKC + NCSGFLG PK + ++ + + + +T K +CF CG+ ++S C C K YH+ CLNL W CP H CDVC + + F S+C + FI K +
Sbjct: 1414 EEGVEHDPGMSASKKLQVERGGGAALKENVCQNCEKLGELLLCEAQCCGAFHLECLGLPEMPRGKFI-----CNECHTGIHTCFVCKQ-----SGEDVKRCLLPLCGKFYHEECVQKYPPTVTQNKG-----FRCPLHICITCHAANPANVSASKGRLMRCVRCPVAYHANDFCLAAGSKILASNSIICPNH--------------FTPRRGCRNHEHV-----------------------NVSWCFVCSEGGSLLCCDSCPAAFHRECLNI-DIPEGNWYCNDCKAGKKPHYREIVWVKVGRYRWWPAEICHPRAVPSNIDKMRHDVGEFPVLFFGSNDYLWTHQARVFPYMEGDVSSKDKMGKGVDGTYKKALQEAAARFEELKAQKELRQLQEDRKNDKKPPPYKHIKVNRPIGRVQIFTADLSEIPRCNCKATD-ENPCGIDSECINRMLLYECHPTVCPAGVRCQNQCFSKRQYPDVEIFRTLQRGWGLRTKTDIKKGEFVNEYVGELIDEEECRARIRYAQEHDITNFYMLTLDKDRIIDAGPKGNYARFMNHCCQPNCETQKWSVNGDTRVGLFALSDIKAGTELTFNYNLECLGNGKTVCKCGAPNCSGFLGVRPK---NQPIVTEEKSRKFKRKPHGKRRSQGEVT-KEREDECFSCGDAGQLVS---CKKPGCPKVYHADCLNL--TKRPAGKWECPWHQCDVCGKEAASFCEMCPSSFCKQHREGMLFISKLD 2095
BLAST of NSD-1 vs. UniProt/SwissProt
Match: sp|Q8BVE8|NSD2_MOUSE (Histone-lysine N-methyltransferase NSD2 OS=Mus musculus OX=10090 GN=Nsd2 PE=1 SV=2) HSP 1 Score: 393.66 bits (1010), Expect = 7.455e-117 Identity = 243/735 (33.06%), Postives = 349/735 (47.48%), Query Frame = 3
Query: 627 PIKYAFDELTLPFVSVKLTNKN--------CRYCLETKNIVQCNKCLFNNFHVKCLEFLQNSIETKINDLDRCLECSLGIIRCYACYKIVDISNEQGFMRCIIKTCTKWFHTNCLETGPMLEMTKFPKPGQLVCPCHICHKCELVNPS-PKYRCTKLIVCIMCPATFHTGDWCIPAGSVELNTGEIICPRHLVDLNFSMNIMVPPFVARVKSDLQERIYGNTLTKISEPMTITPSTVTKPTNVNWCFKCGEGGELLCCETCPAAYHFKCTDLKEIPQKFYCPDCASFCYRSYGEIVWIKCGTHPWWPGQILHLENVPKNIAAKKHANGQFVVQFFGSRDYMWRDHGNVFLYEKEDECNSKTSKYRYNNIFLEGIKEAAIGY----------VTREEKWQSGSCDHVMNSKIYNKIQVNKCPLELRRKVVPETPHCNCISFDPKSDCSIGSGCFNVASKCECDPQICNLGDKCKNQNFVKRIYPKQYTFWANDRGWGLKADEFIKTKQFVNEYIGEIITMEESEKRILWANENNITDFYFMELDNGRLIDARQFSNLSRFINNSCDPNLVAEKWIVNREHRIGLFALRDIQKGEELTFQYNLQNKSSNRIVCKCFSVNCSGFLGEAPKMAXXXXXXXXXXXXXXXXXXXXXXXCKSFLTDKNSNSQCFRCGEIIDMLSSIVCSVGPCMKTYHSVCLNLNMANYVQSSWICPHHYCDVCARPSHHFSSNTTESYCNK 2774
P + A + T VS K + + C+ C +T +++ C FH+ CL L E + C EC+ GI C+ C + ++ RC++ C K++H C++ P+ T F G CP H C C NPS P+ K++ C+ CP +H GD C+ AG + + IIC H F AR + NV+WCF C +GG LLCCE CPAA+H C +++ ++C DC + + +I+W+K G + WWP ++ H +NVP NI KH G+F V FFGS+DY W VF Y + D + +F ++EA + T+E + + H+ +K Y K+Q+ + E P CNC D ++ C S C N EC PQ+C G+ C+NQ F KR YP+ + +GWGL A I+ +FVNEY+GE+I EE RI +A+EN+IT FY + +D R+IDA N SRF+N+SC PN KW VN + R+GLFA+ DI G ELTF YNL + + VC+C + NCSGFLG+ PK + + K K + S +CFRCG+ + ++C C K YH CL L + W CP H+CDVC +PS F S+C +
Sbjct: 640 PYESADETQTEASVSSKKSERGMAAKKEYVCQLCEKTGSLLLCEGPCCGAFHLACL-GLSRRPEGRFT----CTECASGIHSCFVCKE-----SKMEVKRCVVNQCGKFYHEACVKKYPL---TVFESRG-FRCPLHSCMSCHASNPSNPRPSKGKMMRCVRCPVAYHGGDACLAAGCSVIASNSIICTGH--------------FTARKGKRHHTHV-----------------------NVSWCFVCSKGGSLLCCEACPAAFHPDCLNIEMPDGSWFCNDCRAGKKLHFQDIIWVKLGNYRWWPAEVCHPKNVPPNIQKMKHEIGEFPVFFFGSKDYYWTHQARVFPYMEGDRGSRYQGVRGIGRVFKNALQEAEARFNEVKLQREARETQESERKPPPYKHIKVNKPYGKVQIYTAD-------ISEIPKCNCKPTD-ENPCGSDSECLNRMLMFECHPQVCPAGEYCQNQCFTKRQYPETKIIKTDGKGWGLVAKRDIRKGEFVNEYVGELIDEEECMARIKYAHENDITHFYMLTIDKDRIIDAGPKGNYSRFMNHSCQPNCETLKWTVNGDTRVGLFAVCDIPAGTELTFNYNLDCLGNEKTVCRCGASNCSGFLGDRPKTSASLSSEEKGKKAKKKTRRRR----AKGEGKRQSEDECFRCGDGGQL---VLCDRKFCTKAYHLSCLGLGKRPF--GKWECPWHHCDVCGKPSTSFCHLCPNSFCKE 1306
BLAST of NSD-1 vs. UniProt/SwissProt
Match: sp|O96028|NSD2_HUMAN (Histone-lysine N-methyltransferase NSD2 OS=Homo sapiens OX=9606 GN=NSD2 PE=1 SV=1) HSP 1 Score: 390.578 bits (1002), Expect = 7.434e-116 Identity = 237/705 (33.62%), Postives = 338/705 (47.94%), Query Frame = 3
Query: 693 CRYCLETKNIVQCNKCLFNNFHVKCLEFLQNSIETKINDLDRCLECSLGIIRCYACYKIVDISNEQGFMRCIIKTCTKWFHTNCLETGPMLEMTKFPKPGQLVCPCHICHKCELVNPS-PKYRCTKLIVCIMCPATFHTGDWCIPAGSVELNTGEIICPRHLVDLNFSMNIMVPPFVARVKSDLQERIYGNTLTKISEPMTITPSTVTKPTNVNWCFKCGEGGELLCCETCPAAYHFKCTDLKEIPQKFYCPDCASFCYRSYGEIVWIKCGTHPWWPGQILHLENVPKNIAAKKHANGQFVVQFFGSRDYMWRDHGNVFLYEKEDECNSKTSKYRYNNIFLEGIKEAAIGYV----------TREEKWQSGSCDHVMNSKIYNKIQVNKCPLELRRKVVPETPHCNCISFDPKSDCSIGSGCFNVASKCECDPQICNLGDKCKNQNFVKRIYPKQYTFWANDRGWGLKADEFIKTKQFVNEYIGEIITMEESEKRILWANENNITDFYFMELDNGRLIDARQFSNLSRFINNSCDPNLVAEKWIVNREHRIGLFALRDIQKGEELTFQYNLQNKSSNRIVCKCFSVNCSGFLGEAPKMAXXXXXXXXXXXXXXXXXXXXXXXCKSFLTDKNSNSQCFRCGEIIDMLSSIVCSVGPCMKTYHSVCLNLNMANYVQSSWICPHHYCDVCARPSHHFSSNTTESYCNK 2774
C+ C + +++ C FH+ CL L E + C EC+ GI C+ C + ++ RC++ C K++H C++ P+ T F G CP H C C NPS P+ K++ C+ CP +H+GD C+ AG + + IIC H F AR + NV+WCF C +GG LLCCE+CPAA+H C +++ ++C DC + + +I+W+K G + WWP ++ H +NVP NI KH G+F V FFGS+DY W VF Y + D + +F ++EA + T+E + + H+ +K Y K+Q+ + E P CNC D ++ C S C N EC PQ+C G+ C+NQ F KR YP+ + +GWGL A I+ +FVNEY+GE+I EE RI A+EN+IT FY + +D R+IDA N SRF+N+SC PN KW VN + R+GLFA+ DI G ELTF YNL + + VC+C + NCSGFLG+ PK + + K K + S +CFRCG D ++C C K YH CL L + W CP H+CDVC +PS F S+C +
Sbjct: 670 CQLCEKPGSLLLCEGPCCGAFHLACL-GLSRRPEGRFT----CSECASGIHSCFVCKE-----SKTDVKRCVVTQCGKFYHEACVKKYPL---TVFESRG-FRCPLHSCVSCHASNPSNPRPSKGKMMRCVRCPVAYHSGDACLAAGCSVIASNSIICTAH--------------FTARKGKRHHAHV-----------------------NVSWCFVCSKGGSLLCCESCPAAFHPDCLNIEMPDGSWFCNDCRAGKKLHFQDIIWVKLGNYRWWPAEVCHPKNVPPNIQKMKHEIGEFPVFFFGSKDYYWTHQARVFPYMEGDRGSRYQGVRGIGRVFKNALQEAEARFREIKLQREARETQESERKPPPYKHIKVNKPYGKVQIYTAD-------ISEIPKCNCKPTD-ENPCGFDSECLNRMLMFECHPQVCPAGEFCQNQCFTKRQYPETKIIKTDGKGWGLVAKRDIRKGEFVNEYVGELIDEEECMARIKHAHENDITHFYMLTIDKDRIIDAGPKGNYSRFMNHSCQPNCETLKWTVNGDTRVGLFAVCDIPAGTELTFNYNLDCLGNEKTVCRCGASNCSGFLGDRPKTSTTLSSEEKGKKTKKKTRRRR----AKGEGKRQSEDECFRCG---DGGQLVLCDRKFCTKAYHLSCLGLGKRPF--GKWECPWHHCDVCGKPSTSFCHLCPNSFCKE 1306
BLAST of NSD-1 vs. UniProt/SwissProt
Match: sp|Q96L73|NSD1_HUMAN (Histone-lysine N-methyltransferase, H3 lysine-36 specific OS=Homo sapiens OX=9606 GN=NSD1 PE=1 SV=1) HSP 1 Score: 382.489 bits (981), Expect = 5.937e-111 Identity = 240/714 (33.61%), Postives = 349/714 (48.88%), Query Frame = 3
Query: 693 CRYCLETKNIVQCNKCLFNNFHVKCLEFLQNSIETKINDLDRCLECSLGIIRCYACYKIVDISNEQGFMRCIIKTCTKWFHTNCLETGPMLEMTKFPKPGQLVCPCHICHKCELVNPSP-KYRCTKLIVCIMCPATFHTGDWCIPAGSVELNTGEIICPRHLVDLNFSMNIMVPPFVARVKSDLQERIYGNTLTKISEPMTITPSTVTKPTNVNWCFKCGEGGELLCCETCPAAYHFKCTDLKEIPQ-KFYCPDCASFCYRSYGEIVWIKCGTHPWWPGQILHLENVPKNIAAKKHANGQFVVQFFGSRDYMWRDHGNVFLYEKEDECNSKTSKYRYNNIFLEGIKEAAIGY--VTREEKWQSGSCDHVMNSKI--YNKIQVNK--CPLELRRKVVPETPHCNCISFDPKSDCSIGSGCFNVASKCECDPQICNLGDKCKNQNFVKRIYPKQYTFWANDRGWGLKADEFIKTKQFVNEYIGEIITMEESEKRILWANENNITDFYFMELDNGRLIDARQFSNLSRFINNSCDPNLVAEKWIVNREHRIGLFALRDIQKGEELTFQYNLQNKSSNRIVCKCFSVNCSGFLGEAPKMAXXXXXXXXXXXXXXXXXXXXXXXCKSFLTDKNSNSQCFRCGEIIDMLSSIVCSVGPCMKTYHSVCLNLNMANYVQSSWICPHHYCDVCARPSHHFSSNTTESYCNKD-----FIKKFN 2795
C+ C + ++ C FH++CL + I C EC GI C+ C + + + RC++ C K++H C++ P M C HIC C NP+ +L+ C+ CP +H D+C+ AGS L + IICP H F R E + NV+WCF C EGG LLCC++CPAA+H +C ++ +IP+ +YC DC + Y EIVW+K G + WWP +I H VP NI +H G+F V FFGS DY+W VF Y + D + + + + ++EAA + + +++ + D + K Y I+VN+ +++ + E P CNC + D ++ C I S C N EC P +C G +C+NQ F KR YP+ F RGWGL+ IK +FVNEY+GE+I EE RI +A E++IT+FY + LD R+IDA N +RF+N+ C PN +KW VN + R+GLFAL DI+ G ELTF YNL+ + + VCKC + NCSGFLG PK + ++ K + + + +T K +CF CG+ ++S C C K YH+ CLNL W CP H CD+C + + F S+C + FI K +
Sbjct: 1546 CQNCEKLGELLLCEAQCCGAFHLECLGLTEMPRGKFI-----CNECRTGIHTCFVCKQ-----SGEDVKRCLLPLCGKFYHEECVQKYPPTVMQN----KGFRCSLHICITCHAANPANVSASKGRLMRCVRCPVAYHANDFCLAAGSKILASNSIICPNH--------------FTPRRGCRNHEHV-----------------------NVSWCFVCSEGGSLLCCDSCPAAFHRECLNI-DIPEGNWYCNDCKAGKKPHYREIVWVKVGRYRWWPAEICHPRAVPSNIDKMRHDVGEFPVLFFGSNDYLWTHQARVFPYMEGDVSSKDKMGKGVDGTYKKALQEAAARFEELKAQKELRQLQEDRKNDKKPPPYKHIKVNRPIGRVQIFTADLSEIPRCNCKATD-ENPCGIDSECINRMLLYECHPTVCPAGGRCQNQCFSKRQYPEVEIFRTLQRGWGLRTKTDIKKGEFVNEYVGELIDEEECRARIRYAQEHDITNFYMLTLDKDRIIDAGPKGNYARFMNHCCQPNCETQKWSVNGDTRVGLFALSDIKAGTELTFNYNLECLGNGKTVCKCGAPNCSGFLGVRPK---NQPIATEEKSKKFKKKQQGKRRTQGEIT-KEREDECFSCGDAGQLVS---CKKPGCPKVYHADCLNL--TKRPAGKWECPWHQCDICGKEAASFCEMCPSSFCKQHREGMLFISKLD 2197
BLAST of NSD-1 vs. UniProt/SwissProt
Match: sp|O88491|NSD1_MOUSE (Histone-lysine N-methyltransferase, H3 lysine-36 specific OS=Mus musculus OX=10090 GN=Nsd1 PE=1 SV=1) HSP 1 Score: 381.333 bits (978), Expect = 1.585e-110 Identity = 245/745 (32.89%), Postives = 357/745 (47.92%), Query Frame = 3
Query: 606 QEIIKREPIKYAFDELTLPFVSVKLTNKN-CRYCLETKNIVQCNKCLFNNFHVKCLEFLQNSIETKINDLDRCLECSLGIIRCYACYKIVDISNEQGFMRCIIKTCTKWFHTNCLET-GPMLEMTKFPKPGQLVCPCHICHKCELVNPSP-KYRCTKLIVCIMCPATFHTGDWCIPAGSVELNTGEIICPRHLVDLNFSMNIMVPPFVARVKSDLQERIYGNTLTKISEPMTITPSTVTKPTNVNWCFKCGEGGELLCCETCPAAYHFKCTDLKEIPQ-KFYCPDCASFCYRSYGEIVWIKCGTHPWWPGQILHLENVPKNIAAKKHANGQFVVQFFGSRDYMWRDHGNVFLYEKEDECNSKTSKYRYNNIFLEGIKEAAIGY----VTREEKWQSGSCDHVMNSKIYNKIQVNK--CPLELRRKVVPETPHCNCISFDPKSDCSIGSGCFNVASKCECDPQICNLGDKCKNQNFVKRIYPKQYTFWANDRGWGLKADEFIKTKQFVNEYIGEIITMEESEKRILWANENNITDFYFMELDNGRLIDARQFSNLSRFINNSCDPNLVAEKWIVNREHRIGLFALRDIQKGEELTFQYNLQNKSSNRIVCKCFSVNCSGFLGEAPKMAXXXXXXXXXXXXXXXXXXXXXXXCKSFLTDKNSNSQCFRCGEIIDMLSSIVCSVGPCMKTYHSVCLNLNMANYVQSSWICPHHYCDVCARPSHHFSSNTTESYCNKD-----FIKKFN 2795
+E ++ +P A +L + +N C+ C + ++ C FH++CL + I C EC GI C+ C + + + RC++ C K++H C++ P + K CP HIC C NP+ +L+ C+ CP +H D+C+ AGS L + IICP H F R E + NV+WCF C EGG LLCC++CPAA+H +C ++ +IP+ +YC DC + Y EIVW+K G + WWP +I H VP NI +H G+F V FFGS DY+W VF Y + D + + + + ++EAA + +E + + Y I+VN+ +++ + E P CNC + D ++ C I S C N EC P +C G +C+NQ F KR YP F RGWGL+ IK +FVNEY+GE+I EE RI +A E++IT+FY + LD R+IDA N +RF+N+ C PN +KW VN + R+GLFAL DI+ G ELTF YNL+ + + VCKC + NCSGFLG PK + ++ + + + +T K +CF CG+ ++S C C K YH+ CLNL W CP H CDVC + + F S+C + FI K +
Sbjct: 1414 EEGVEHDPGMSASKKLQVERGGGAALKENVCQNCEKLGELLLCEAQCCGAFHLECLGLPEMPRGKFI-----CNECHTGIHTCFVCKQ-----SGEDVKRCLLPLCGKFYHEECVQKYPPTVTQNKG-----FRCPLHICITCHAANPANVSASKGRLMRCVRCPVAYHANDFCLAAGSKILASNSIICPNH--------------FTPRRGCRNHEHV-----------------------NVSWCFVCSEGGSLLCCDSCPAAFHRECLNI-DIPEGNWYCNDCKAGKKPHYREIVWVKVGRYRWWPAEICHPRAVPSNIDKMRHDVGEFPVLFFGSNDYLWTHQARVFPYMEGDVSSKDKMGKGVDGTYKKALQEAAARFEELKARKELRQLQEDRKNDKKPPPYKHIKVNRPIGRVQIFTADLSEIPRCNCKATD-ENPCGIDSECINRMLLYECHPTVCPAGVRCQNQCFSKRQYPDVEIFRTLQRGWGLRTKTDIKKGEFVNEYVGELIDEEECRARIRYAQEHDITNFYMLTLDKDRIIDAGPKGNYARFMNHCCQPNCETQKWSVNGDTRVGLFALSDIKAGTELTFNYNLECLGNGKTVCKCGAPNCSGFLGVRPK---NQPIVTEEKSRKFKRKPHGKRRSQGEVT-KEREDECFSCGDAGQLVS---CKKPGCPKVYHADCLNL--TKRPAGKWECPWHQCDVCGKEAASFCEMCPSSFCKQHREGMLFISKLD 2095
BLAST of NSD-1 vs. UniProt/SwissProt
Match: sp|Q6P2L6|NSD3_MOUSE (Histone-lysine N-methyltransferase NSD3 OS=Mus musculus OX=10090 GN=Nsd3 PE=1 SV=2) HSP 1 Score: 358.221 bits (918), Expect = 7.865e-104 Identity = 242/730 (33.15%), Postives = 348/730 (47.67%), Query Frame = 3
Query: 693 CRYCLETKN-IVQCNKCLFNNFHVKCLEFLQNSIETKINDLD-RCLECSLGIIRCYACYKIVDISNEQGFMRCIIKTCTKWFHTNCLETGP--MLEMTKFPKPGQLVCPCHICHKCELVNPSPKYRCTKLIVCIMCPATFHTGDWCIPAGSVELNTGEIICPRHLVDLNFSMNIMVP-------PFVARVKSDLQERIYG----------NTLTKISEPMTITPSTVTKPTNVNWCFKCGEGGELLCCETCPAAYHFKCTDLKEIPQK-FYCPDCASFCYRSYGEIVWIKCGTHP---WWPGQILHLENVPKNIAAKKHANGQFVVQFFGSRDYMWRDHGNVFLYEKEDECNSKTSKYRYNNIFLEGIKEAAIGYVTREEKWQSGSC-------------DHVMNSKIYNKIQVNKCPLELRRKVVPETPHCNCISFDPKSDCSIGSGCFNVASKCECDPQICNLGDKCKNQNFVKRIYPKQYTFWANDRGWGLKADEFIKTKQFVNEYIGEIITMEESEKRILWANENNITDFYFMELDNGRLIDARQFSNLSRFINNSCDPNLVAEKWIVNREHRIGLFALRDIQKGEELTFQYNLQNKSSNRIVCKCFSVNCSGFLGEAPKMAXXXXXXXXXXXXXXXXXXXXXXXCKSFLTDKNSNSQCFRCGEIIDMLSSIVCSVGPCMKTYHSVCLNLNMANYVQSSWICPHHYCDVCARPSHHFSSNTTESYC 2768
C+ C + + +V C +FHV+CL T + + C EC G C++C +S + RC + C K++H C+ P + E F CP H C C + K +++ C+ CP +H GD C+ AGSV +++ +IC H + S I V + + SD Y N + PM + S K +C +GG LLCCE+CPA++H +C + ++P+ + C DC + Y +IVW+K G + WWP +I +VP NI KH G F V FFGS DY W G VF Y + D+ + + N F + ++EAA + + + +S H+ +K+ K+QV L E P CNC D ++ C + S C N S+ EC PQ+C GD+C+NQ F KR+YP RGWGL+ IK +FVNEY+GE+I EE RI A+EN++T+FY + + R+IDA N SRF+N+SC+PN +KW VN + R+GLFAL DI G ELTF YNL + R VC C + NCSGFLG PK A S + T + ++ K D CF+CG+ ++ ++C C K YH +CLNL + W CP H CD C + F S+C
Sbjct: 704 CQVCEKAGDCLVACEGECCRHFHVECLGL------TAVPEGHFTCEECETGQHPCFSC----KVSGKD-VKRCSVSVCGKFYHEACVRKFPTAIFESKGF------RCPQHCCSSCSMEKDIHKASKGRMMRCLRCPVAYHVGDACVAAGSVSVSSHILICSNHSKRSSQSAAINVGFCFVCARGLIVQDHSDPMFSSYAYKSHYLLSESNRAELMKLPMIPSSSASKK--------RCEKGGRLLCCESCPASFHPECLSI-DMPEGCWNCNDCKAGKKLHYKQIVWVKLGNYRQVLWWPAEICSPRSVPLNIQGLKHDLGDFPVFFFGSHDYYWVHQGRVFPYVEGDK-HFAEGQTSINKTFKKALEEAAKRFQELKAQRESKEALEMERTSRKPPPYKHIKANKVIGKVQVQVADLS-------EIPRCNCKPGD-ENPCGLESQCLNRMSQYECHPQVCPAGDRCQNQCFTKRLYPDAEVIKTERRGWGLRTKRSIKKGEFVNEYVGELIDEEECRLRIKRAHENSVTNFYMLTVTKDRIIDAGPKGNYSRFMNHSCNPNCETQKWTVNGDVRVGLFALCDIPAGMELTFNYNLDCLGNGRTVCHCGADNCSGFLGVRPKSACTSAVDEKTKNAKLKKRRKVKAEAKPIHED-----YCFQCGDGGEL---VMCDKKDCPKAYHLLCLNLTQPPH--GKWECPWHRCDECGSVAVSFCEFCPHSFC 1388
BLAST of NSD-1 vs. TrEMBL
Match: H9CXT1 (NSD-1 OS=Schmidtea mediterranea OX=79327 PE=2 SV=1) HSP 1 Score: 1726.07 bits (4469), Expect = 0.000e+0 Identity = 914/914 (100.00%), Postives = 914/914 (100.00%), Query Frame = 3
Query: 57 MLFXXXXXXXXXXXMFKEXXXXXXXXXXXXXXXXXXXRTEDSRSKSYKVGQIICGKVGKYPWWPCMVNTIPTSNEPRVLVSYFGKKNDYSYLFDDCTMYAQTKSDFENIFKLHNHDKKTLARLAHYKKQLDLAWKEVEIASLLDENSRFELYKIKCEIKESINXXXXXXXXXXXXXXXXXXXXQEIIKREPIKYAFDELTLPFVSVKLTNKNCRYCLETKNIVQCNKCLFNNFHVKCLEFLQNSIETKINDLDRCLECSLGIIRCYACYKIVDISNEQGFMRCIIKTCTKWFHTNCLETGPMLEMTKFPKPGQLVCPCHICHKCELVNPSPKYRCTKLIVCIMCPATFHTGDWCIPAGSVELNTGEIICPRHLVDLNFSMNIMVPPFVARVKSDLQERIYGNTLTKISEPMTITPSTVTKPTNVNWCFKCGEGGELLCCETCPAAYHFKCTDLKEIPQKFYCPDCASFCYRSYGEIVWIKCGTHPWWPGQILHLENVPKNIAAKKHANGQFVVQFFGSRDYMWRDHGNVFLYEKEDECNSKTSKYRYNNIFLEGIKEAAIGYVTREEKWQSGSCDHVMNSKIYNKIQVNKCPLELRRKVVPETPHCNCISFDPKSDCSIGSGCFNVASKCECDPQICNLGDKCKNQNFVKRIYPKQYTFWANDRGWGLKADEFIKTKQFVNEYIGEIITMEESEKRILWANENNITDFYFMELDNGRLIDARQFSNLSRFINNSCDPNLVAEKWIVNREHRIGLFALRDIQKGEELTFQYNLQNKSSNRIVCKCFSVNCSGFLGEAPKMAXXXXXXXXXXXXXXXXXXXXXXXCKSFLTDKNSNSQCFRCGEIIDMLSSIVCSVGPCMKTYHSVCLNLNMANYVQSSWICPHHYCDVCARPSHHFSSNTTESYCNKDFIKKFNS 2798
MLFNSIIINSISYNMFKELTNLNNNSSNVSLLSTSSNRTEDSRSKSYKVGQIICGKVGKYPWWPCMVNTIPTSNEPRVLVSYFGKKNDYSYLFDDCTMYAQTKSDFENIFKLHNHDKKTLARLAHYKKQLDLAWKEVEIASLLDENSRFELYKIKCEIKESINPPKKRIRPPKPKKEKAASKPQEIIKREPIKYAFDELTLPFVSVKLTNKNCRYCLETKNIVQCNKCLFNNFHVKCLEFLQNSIETKINDLDRCLECSLGIIRCYACYKIVDISNEQGFMRCIIKTCTKWFHTNCLETGPMLEMTKFPKPGQLVCPCHICHKCELVNPSPKYRCTKLIVCIMCPATFHTGDWCIPAGSVELNTGEIICPRHLVDLNFSMNIMVPPFVARVKSDLQERIYGNTLTKISEPMTITPSTVTKPTNVNWCFKCGEGGELLCCETCPAAYHFKCTDLKEIPQKFYCPDCASFCYRSYGEIVWIKCGTHPWWPGQILHLENVPKNIAAKKHANGQFVVQFFGSRDYMWRDHGNVFLYEKEDECNSKTSKYRYNNIFLEGIKEAAIGYVTREEKWQSGSCDHVMNSKIYNKIQVNKCPLELRRKVVPETPHCNCISFDPKSDCSIGSGCFNVASKCECDPQICNLGDKCKNQNFVKRIYPKQYTFWANDRGWGLKADEFIKTKQFVNEYIGEIITMEESEKRILWANENNITDFYFMELDNGRLIDARQFSNLSRFINNSCDPNLVAEKWIVNREHRIGLFALRDIQKGEELTFQYNLQNKSSNRIVCKCFSVNCSGFLGEAPKMAKVSKLKSDTSKKSKGDTTESESSCKSFLTDKNSNSQCFRCGEIIDMLSSIVCSVGPCMKTYHSVCLNLNMANYVQSSWICPHHYCDVCARPSHHFSSNTTESYCNKDFIKKFNS
Sbjct: 1 MLFNSIIINSISYNMFKELTNLNNNSSNVSLLSTSSNRTEDSRSKSYKVGQIICGKVGKYPWWPCMVNTIPTSNEPRVLVSYFGKKNDYSYLFDDCTMYAQTKSDFENIFKLHNHDKKTLARLAHYKKQLDLAWKEVEIASLLDENSRFELYKIKCEIKESINPPKKRIRPPKPKKEKAASKPQEIIKREPIKYAFDELTLPFVSVKLTNKNCRYCLETKNIVQCNKCLFNNFHVKCLEFLQNSIETKINDLDRCLECSLGIIRCYACYKIVDISNEQGFMRCIIKTCTKWFHTNCLETGPMLEMTKFPKPGQLVCPCHICHKCELVNPSPKYRCTKLIVCIMCPATFHTGDWCIPAGSVELNTGEIICPRHLVDLNFSMNIMVPPFVARVKSDLQERIYGNTLTKISEPMTITPSTVTKPTNVNWCFKCGEGGELLCCETCPAAYHFKCTDLKEIPQKFYCPDCASFCYRSYGEIVWIKCGTHPWWPGQILHLENVPKNIAAKKHANGQFVVQFFGSRDYMWRDHGNVFLYEKEDECNSKTSKYRYNNIFLEGIKEAAIGYVTREEKWQSGSCDHVMNSKIYNKIQVNKCPLELRRKVVPETPHCNCISFDPKSDCSIGSGCFNVASKCECDPQICNLGDKCKNQNFVKRIYPKQYTFWANDRGWGLKADEFIKTKQFVNEYIGEIITMEESEKRILWANENNITDFYFMELDNGRLIDARQFSNLSRFINNSCDPNLVAEKWIVNREHRIGLFALRDIQKGEELTFQYNLQNKSSNRIVCKCFSVNCSGFLGEAPKMAKVSKLKSDTSKKSKGDTTESESSCKSFLTDKNSNSQCFRCGEIIDMLSSIVCSVGPCMKTYHSVCLNLNMANYVQSSWICPHHYCDVCARPSHHFSSNTTESYCNKDFIKKFNS 914
BLAST of NSD-1 vs. TrEMBL
Match: A0A2T7PCE1 (Uncharacterized protein OS=Pomacea canaliculata OX=400727 GN=C0Q70_10357 PE=4 SV=1) HSP 1 Score: 411.379 bits (1056), Expect = 1.659e-120 Identity = 246/703 (34.99%), Postives = 351/703 (49.93%), Query Frame = 3
Query: 693 CRYCLETKNIVQCNKCLFNNFHVKCLEFLQNSIETKINDLDRCLECSLGIIRCYACYKIVDISNEQGFMRCIIKTCTKWFHTNCLETGPMLEMTKFPKPGQLVCPCHICHKCELVN-PSPKYRCTKLIVCIMCPATFHTGDWCIPAGSVELNTGEIICPRHLVDLNFSMNIMVPPFVARVKSDLQERIYGNTLTKISEPMTITPSTVTKPTNVNWCFKCGEGGELLCCETCPAAYHFKCTDLKEIPQK-FYCPDCASFCYRSYGEIVWIKCGTHPWWPGQILHLENVPKNIAAKKHANGQFVVQFFGSRDYMWRDHGNVFLYEKEDECNSKTSKYR-YNNIFLEGIKEAAIGYV------TREEKWQSGSCDHVMNSKIYNKIQVNKCPLELRRKVVPETPHCNCISFDPKSDCSIGSGCFNVASKCECDPQICNLGDKCKNQNFVKRIYPKQYTFWANDRGWGLKADEFIKTKQFVNEYIGEIITMEESEKRILWANENNITDFYFMELDNGRLIDARQFSNLSRFINNSCDPNLVAEKWIVNREHRIGLFALRDIQKGEELTFQYNLQNKSSNRIVCKCFSVNCSGFLGEAPKMAXXXXXXXXXXXXXXXXXXXXXXXCKSFLTDKNSNSQCFRCGEIIDMLSSIVCSVGPCMKTYHSVCLNLNMANYVQSSWICPHHYCDVCARPSHHFSSNTTESYCNK 2774
C C + +++C+ + FH CL+ L+ E RC EC GI C+AC K ++ RC + C K++H C++ P M + +CP H+C C N +PK +L+ C+ CP +H GD+CI AGS L I+C H L + + RI NV+WCF C +GG L+CCETCPAA+H +C L +P+ +YC DCA YG+I+WIK G + WWPG+I H NVP NI K H G+F V+FFGS D+ W G VFL+++ D + S R ++ +G+KEA + +E+ + D + K V +++ + + E P C C D ++ C + C N EC PQ+C + C NQ F KR YP + RGWGLK IK QFV EY+G+++ +E ++RI A+E NIT+FY + LD R+IDA N SRF+N+SC+PNL +KW VN + R+GLF L+DI G ELTF YNL+ + + C C S CSGFLG PK A + ++ +K + K K +CFRCGE ++ ++C C K YH CLNL A W+CP H+CDVC + ++ S S+C +
Sbjct: 592 CTVCEQAGELIECHGPCQSYFHTSCLK-LEKEPEADF----RCSECCAGIHSCFACKK-----QDKEVRRCSVSQCGKFYHEECVKKLPQARM----EGKGFICPLHVCATCAADNIRNPKAVKGRLLRCVRCPTAYHVGDFCIAAGSKHLAGYHIVCSGHFKPLKSQAHHV--------------RI-----------------------NVSWCFSCSKGGSLVCCETCPAAFHIECAHLDSMPEDAWYCSDCAHGKRPLYGDIIWIKIGNYRWWPGEICHPRNVPVNIQEKAHQVGEFPVRFFGSHDFYWTHQGRVFLFQEGDRGSKDISACRGLFKMYCKGVKEATEAFKLWKAAKMNKEQLEQERNDRKPAPYKFVKANVPVGNVQIHKADLSEIPRCECRP-DQENPCGSDTECLNRMLMYECHPQVCPAKESCHNQRFQKRQYPDLLPYRTESRGWGLKTLMDIKKGQFVIEYVGDLVDEDECKRRIAQAHEENITNFYMLTLDKNRIIDAGPKGNYSRFMNHSCEPNLETQKWTVNGDIRVGLFTLKDIPAGSELTFNYNLECLGNEKTKCSCGSDICSGFLGVRPKTAAAAHMEKRKREKDARKKKKK----KKLDVKKEHEDECFRCGEGGEL---VMCDKPNCPKVYHLQCLNL--AKPPHGKWLCPWHHCDVCGKLANKLCSECPNSFCQQ 1233
BLAST of NSD-1 vs. TrEMBL
Match: A0A267ERM7 (Uncharacterized protein (Fragment) OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig026212g1 PE=4 SV=1) HSP 1 Score: 403.675 bits (1036), Expect = 2.243e-120 Identity = 256/749 (34.18%), Postives = 356/749 (47.53%), Query Frame = 3
Query: 633 KYAFDELTLPFVSVKLTNKNCRYCLETKNIVQCNKCLFNNFHVKCLEFLQNSIETKINDL--DRCLECSLGIIRCYACYKIVDISNEQGFMRCIIKTCTKWFHTNCLETGPMLEMTKFPKPGQLVCPCHICHKCELVNPSP----KYRCT---KLIVCIMCPATFHTGDWCIPAGSVELNTGEIICPRHLVDLNFSMNIMVPPFVARVKSDLQERIYGNTLTKISEPMTITPSTVTKPTNVNWCFKCGEGGELLCCETCPAAYHFKCTDLKEIPQKFYCPDCASFCYRSYGEIVWIKCGTHPWWPGQILHLENVPKNIAAKKHANGQFVVQFFGSRDYMWRDHGNVFLYEKED--ECNSKTSKYRYNNIFLEGIKEAAIG-YVTREEKWQSGSCDHVMNSKIYNKIQVNKCPLELRR----KVVPETPHCNCISFDPKSDCSIGSGCFNVASKCECDPQICNLGDKCKNQNFVKRIYPKQYTFWAND--RGWGLKADEFIKTKQFVNEYIGEIITMEESEKRILWANENNITDFYFMELDNGRLIDARQFSNLSRFINNSCDPNLVAEKWIVNREHRIGLFALRDIQKGEELTFQYNLQNKSSNRIVCKCFSVNCSGFLGEAPKMAX-------------------XXXXXXXXXXXXXXXXXXXXXXCKSFLTDKNSNSQCFRCGEIIDMLSSIVCSVGPCMKTYHSVCLNLNMANYVQSSWICPHHYCDVCARPSHHFSSNTTESYC 2768
++ F L SVK C C ++ C+ C FH CL + + + +C +C+ G C+ C + + ++ +RC I C K +H C + P ++ LVCP H C C + PS R T KL+ C+ CPA +H GD+C+PAGS EL+ I+CP HL D K NV WCF C +GG L+CCE CPA++H +C L E+P++F C DC YG+IVW+K G WWP +IL+ ++ P NI H G F V FFG+ +Y W G VF +E D + R +F EG++ A + RE + + Y I+ N P R + E C+C S D + C S C N EC P +C D+C NQ FVKR YP Q F N RGWGLKA + I +FVNEY+G++I EE++KR+ WA+++ +T+FY + LD GR+IDA NLSRF+N+SC PNLV +KW VN + RIGLFALRDI+ GEELTF YN + + ++ C+C + NCSGFLG P+ + ++ + + + + CK D C+RC + +M I+C C K YH CL L+ A W CP H+CD C RP+ S SYC
Sbjct: 334 RFEFQRLLHAPSSVKRA-PVCSKCELGGEVIPCDSCCLQ-FHAVCLADGAAAADAADGEAGAKKCADCAAGRQLCFLCKQD---AGDKRMLRCHINGCGKQYHDACAGSMPFAKVESR----GLVCPQHACLACCVDAPSSAPGSSGRATGAAKLVRCVRCPAAYHGGDFCVPAGSEELSETCIVCPEHLRD-----------------------------------------KAAKTINVAWCFICSQGGSLVCCERCPASFHPECLKLSELPEQFTCDDCRMGRQPRYGDIVWVKVGHFRWWPCEILYPDHAPLNIQRMAHQKGTFPVHFFGTDEYYWVHKGRVFEFEDGDLGDLRKTQGSSRLVQLFKEGVRLAQEACRLFREMRENRDKMEQSKKPPPYKFIRTNY-PFGNARVYKAADLSELHRCDC-SADSQEPCGSDSDCMNRVLYYECHPGLCAAKDRCLNQRFVKREYPTQAVFKTNQGGRGWGLKAMQDIAKGEFVNEYVGDLIDEEEAKKRLSWAHDHGVTNFYMLTLDKGRIIDAGPKGNLSRFMNHSCSPNLVTQKWSVNGDLRIGLFALRDIKAGEELTFNYNFECLGAEKLACQCGAENCSGFLGVRPRSSANLLRDAAASSGGGGGGGGDGAESGKKRRRTKGVASGTTGAVCKVVYED-----TCYRCCDGGEM---IMCDKEACPKVYHLGCLGLSKAP--SGKWYCPWHHCDECGRPATVLCSECPGSYC 1020
BLAST of NSD-1 vs. TrEMBL
Match: A0A267FZR2 (Uncharacterized protein (Fragment) OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig014479g2 PE=4 SV=1) HSP 1 Score: 403.675 bits (1036), Expect = 2.618e-120 Identity = 256/749 (34.18%), Postives = 356/749 (47.53%), Query Frame = 3
Query: 633 KYAFDELTLPFVSVKLTNKNCRYCLETKNIVQCNKCLFNNFHVKCLEFLQNSIETKINDL--DRCLECSLGIIRCYACYKIVDISNEQGFMRCIIKTCTKWFHTNCLETGPMLEMTKFPKPGQLVCPCHICHKCELVNPSP----KYRCT---KLIVCIMCPATFHTGDWCIPAGSVELNTGEIICPRHLVDLNFSMNIMVPPFVARVKSDLQERIYGNTLTKISEPMTITPSTVTKPTNVNWCFKCGEGGELLCCETCPAAYHFKCTDLKEIPQKFYCPDCASFCYRSYGEIVWIKCGTHPWWPGQILHLENVPKNIAAKKHANGQFVVQFFGSRDYMWRDHGNVFLYEKED--ECNSKTSKYRYNNIFLEGIKEAAIG-YVTREEKWQSGSCDHVMNSKIYNKIQVNKCPLELRR----KVVPETPHCNCISFDPKSDCSIGSGCFNVASKCECDPQICNLGDKCKNQNFVKRIYPKQYTFWAND--RGWGLKADEFIKTKQFVNEYIGEIITMEESEKRILWANENNITDFYFMELDNGRLIDARQFSNLSRFINNSCDPNLVAEKWIVNREHRIGLFALRDIQKGEELTFQYNLQNKSSNRIVCKCFSVNCSGFLGEAPKMAX-------------------XXXXXXXXXXXXXXXXXXXXXXCKSFLTDKNSNSQCFRCGEIIDMLSSIVCSVGPCMKTYHSVCLNLNMANYVQSSWICPHHYCDVCARPSHHFSSNTTESYC 2768
++ F L SVK C C ++ C+ C FH CL + + + +C +C+ G C+ C + + ++ +RC I C K +H C + P ++ LVCP H C C + PS R T KL+ C+ CPA +H GD+C+PAGS EL+ I+CP HL D K NV WCF C +GG L+CCE CPA++H +C L E+P++F C DC YG+IVW+K G WWP +IL+ ++ P NI H G F V FFG+ +Y W G VF +E D + R +F EG++ A + RE + + Y I+ N P R + E C+C S D + C S C N EC P +C D+C NQ FVKR YP Q F N RGWGLKA + I +FVNEY+G++I EE++KR+ WA+++ +T+FY + LD GR+IDA NLSRF+N+SC PNLV +KW VN + RIGLFALRDI+ GEELTF YN + + ++ C+C + NCSGFLG P+ + ++ + + + + CK D C+RC + +M I+C C K YH CL L+ A W CP H+CD C RP+ S SYC
Sbjct: 334 RFEFQRLLHAPSSVKRA-PVCSKCELGGEVIPCDSCCLQ-FHAVCLADGAAAADAADGEAGAKKCADCAAGRQLCFLCKQD---AGDKRMLRCHINGCGKQYHDACAGSMPFAKVESR----GLVCPQHACLACCVDAPSSAPGSSGRATGAAKLVRCVRCPAAYHGGDFCVPAGSEELSETCIVCPEHLRD-----------------------------------------KAAKTINVAWCFICSQGGSLVCCERCPASFHPECLKLSELPEQFTCDDCRMGRQPRYGDIVWVKVGHFRWWPCEILYPDHAPLNIQRMAHQKGTFPVHFFGTDEYYWVHKGRVFEFEDGDLGDLRKTQGSSRLVQLFKEGVRLAQEACRLFREMRENRDKMEQSKKPPPYKFIRTNY-PFGNARVYKAADLSELHRCDC-SADSQEPCGSDSDCMNRVLYYECHPGLCAAKDRCLNQRFVKREYPTQAVFKTNQGGRGWGLKAMQDIAKGEFVNEYVGDLIDEEEAKKRLSWAHDHGVTNFYMLTLDKGRIIDAGPKGNLSRFMNHSCSPNLVTQKWSVNGDLRIGLFALRDIKAGEELTFNYNFECLGAEKLACQCGAENCSGFLGVRPRSSANLLRDAAASSGGGGGGGGDGAESGKKRRRTKGVASGTTGAVCKVVYED-----TCYRCCDGGEM---IMCDKEACPKVYHLGCLGLSKAP--SGKWYCPWHHCDECGRPATVLCSECPGSYC 1020
BLAST of NSD-1 vs. TrEMBL
Match: A0A1I8IAL6 (Histone-lysine N-methyltransferase OS=Macrostomum lignano OX=282301 PE=4 SV=1) HSP 1 Score: 403.675 bits (1036), Expect = 2.722e-120 Identity = 256/749 (34.18%), Postives = 356/749 (47.53%), Query Frame = 3
Query: 633 KYAFDELTLPFVSVKLTNKNCRYCLETKNIVQCNKCLFNNFHVKCLEFLQNSIETKINDL--DRCLECSLGIIRCYACYKIVDISNEQGFMRCIIKTCTKWFHTNCLETGPMLEMTKFPKPGQLVCPCHICHKCELVNPSP----KYRCT---KLIVCIMCPATFHTGDWCIPAGSVELNTGEIICPRHLVDLNFSMNIMVPPFVARVKSDLQERIYGNTLTKISEPMTITPSTVTKPTNVNWCFKCGEGGELLCCETCPAAYHFKCTDLKEIPQKFYCPDCASFCYRSYGEIVWIKCGTHPWWPGQILHLENVPKNIAAKKHANGQFVVQFFGSRDYMWRDHGNVFLYEKED--ECNSKTSKYRYNNIFLEGIKEAAIG-YVTREEKWQSGSCDHVMNSKIYNKIQVNKCPLELRR----KVVPETPHCNCISFDPKSDCSIGSGCFNVASKCECDPQICNLGDKCKNQNFVKRIYPKQYTFWAND--RGWGLKADEFIKTKQFVNEYIGEIITMEESEKRILWANENNITDFYFMELDNGRLIDARQFSNLSRFINNSCDPNLVAEKWIVNREHRIGLFALRDIQKGEELTFQYNLQNKSSNRIVCKCFSVNCSGFLGEAPKMAX-------------------XXXXXXXXXXXXXXXXXXXXXXCKSFLTDKNSNSQCFRCGEIIDMLSSIVCSVGPCMKTYHSVCLNLNMANYVQSSWICPHHYCDVCARPSHHFSSNTTESYC 2768
++ F L SVK C C ++ C+ C FH CL + + + +C +C+ G C+ C + + ++ +RC I C K +H C + P ++ LVCP H C C + PS R T KL+ C+ CPA +H GD+C+PAGS EL+ I+CP HL D K NV WCF C +GG L+CCE CPA++H +C L E+P++F C DC YG+IVW+K G WWP +IL+ ++ P NI H G F V FFG+ +Y W G VF +E D + R +F EG++ A + RE + + Y I+ N P R + E C+C S D + C S C N EC P +C D+C NQ FVKR YP Q F N RGWGLKA + I +FVNEY+G++I EE++KR+ WA+++ +T+FY + LD GR+IDA NLSRF+N+SC PNLV +KW VN + RIGLFALRDI+ GEELTF YN + + ++ C+C + NCSGFLG P+ + ++ + + + + CK D C+RC + +M I+C C K YH CL L+ A W CP H+CD C RP+ S SYC
Sbjct: 342 RFEFQRLLHAPSSVKRA-PVCSKCELGGEVIPCDSCCLQ-FHAVCLADGAAAADAADGEAGAKKCADCAAGRQLCFLCKQD---AGDKRMLRCHINGCGKQYHDACAGSMPFAKVESR----GLVCPQHACLACCVDAPSSAPGSSGRATGAAKLVRCVRCPAAYHGGDFCVPAGSEELSETCIVCPEHLRD-----------------------------------------KAAKTINVAWCFICSQGGSLVCCERCPASFHPECLKLSELPEQFTCDDCRMGRQPRYGDIVWVKVGHFRWWPCEILYPDHAPLNIQRMAHQKGTFPVHFFGTDEYYWVHKGRVFEFEDGDLGDLRKTQGSSRLVQLFKEGVRLAQEACRLFREMRENRDKMEQSKKPPPYKFIRTNY-PFGNARVYKAADLSELHRCDC-SADSQEPCGSDSDCMNRVLYYECHPGLCAAKDRCLNQRFVKREYPTQAVFKTNQGGRGWGLKAMQDIAKGEFVNEYVGDLIDEEEAKKRLSWAHDHGVTNFYMLTLDKGRIIDAGPKGNLSRFMNHSCSPNLVTQKWSVNGDLRIGLFALRDIKAGEELTFNYNFECLGAEKLACQCGAENCSGFLGVRPRSSANLLRDAAASSGGGGGGGGDGAESGKKRRRTKGVASGTTGAVCKVVYED-----TCYRCCDGGEM---IMCDKEACPKVYHLGCLGLSKAP--SGKWYCPWHHCDECGRPATVLCSECPGSYC 1028
BLAST of NSD-1 vs. Ensembl Cavefish
Match: nsd2 (nuclear receptor binding SET domain protein 2 [Source:ZFIN;Acc:ZDB-GENE-030131-2581]) HSP 1 Score: 393.66 bits (1010), Expect = 1.083e-117 Identity = 241/698 (34.53%), Postives = 342/698 (49.00%), Query Frame = 3
Query: 693 CRYCLET-KNIVQCNKCLFNNFHVKCLEFLQNSIETKINDLDRCLECSLGIIRCYACYKIVDISNEQGFMRCIIKTCTKWFHTNCLETGPMLEMTKFPKPGQLVCPCHICHKCELVN-PSPKYRCTKLIVCIMCPATFHTGDWCIPAGSVELNTGEIICPRHL-VDLNFSMNIMVPPFVARVKSDLQERIYGNTLTKISEPMTITPSTVTKPTNVNWCFKCGEGGELLCCETCPAAYHFKCTDLKEIPQKFYCPDCASFCYRSYGEIVWIKCGTHPWWPGQILHLENVPKNIAAKKHANGQFVVQFFGSRDYMWRDHGNVFLYEKEDECNSKTSKYRYNNIFLEGIKEAAIGYVT-REEKWQSGSCDHVMNSKIYNKIQVNK--CPLELRRKVVPETPHCNCISFDPKSDCSIGSGCFNVASKCECDPQICNLGDKCKNQNFVKRIYPKQYTFWANDRGWGLKADEFIKTKQFVNEYIGEIITMEESEKRILWANENNITDFYFMELDNGRLIDARQFSNLSRFINNSCDPNLVAEKWIVNREHRIGLFALRDIQKGEELTFQYNLQNKSSNRIVCKCFSVNCSGFLGEAPKMAXXXXXXXXXXXXXXXXXXXXXXXCKSFLTDKNSNSQCFRCGEIIDMLSSIVCSVGPCMKTYHSVCLNLNMANYVQSSWICPHHYCDVCARPSHHFSSNTTESYC 2768
C+ C +T +++V C F +H++CL + D C C G+ C+ C + +E RC + C K++H CL + +T F G CP H C C N + K K+I C+ CP +H GD C+ AGS L + I+C H +S + V NV+WCF C +GG LLCCE+CPAA+H C ++ ++C DC S Y +I+W+K G + WWP +I H N+P NI +H G+F V FFGS+DY W G VF Y + D S+ + +F + EA + + E+ + ++ Y I+ NK +++ + E P CNC D + CS S C N EC PQ+C G++C NQ+F KR+YP+ T +GWGL IK +FVNEY+GE+I EE RI +A EN+IT FY + ++ R+IDA N SRF+N+SC PN +KW VN + R+GLFA+ DI G ELTF YNL + + VC+C + NCSGFLG+ PK+A S+ KS KK K S +CFRCG+ + ++C C K YH CL+ + W CP H+CDVC +PS F + S+C
Sbjct: 686 CQVCEKTSEDLVTCEGHCFATYHLQCLGLDHPT------DKVLCTACRTGVHACFTCKQ-----SEGEVKRCSVLHCGKYYHEACLR---LSALTVFDNRG-FRCPLHTCLSCHYSNRGTAKATKGKMIRCLRCPVAYHAGDLCVAAGSEMLTSTAIVCTNHFNPKKGYSHHSHV--------------------------------------NVSWCFICSKGGRLLCCESCPAAFHPDCLNIAMPDGSWFCNDCRSGKKPKYRDIIWVKLGNYRWWPAEIRHPRNIPTNIQHLRHEIGEFPVYFFGSKDYFWTHQGRVFPYIEGDR-GSRHQRNGIGKVFKTALLEAETRFKQIKMEREAKEAHENNKKPPPYKYIKTNKPCGRVQIYTADISEIPKCNCKPTDERP-CSFESECLNRMLLYECHPQVCPAGERCMNQDFTKRLYPETKTIRTAGKGWGLLTLRDIKKGEFVNEYVGELIDEEECRARIRYAQENDITHFYMLTINKDRIIDAGPKGNYSRFMNHSCQPNCETQKWTVNGDTRVGLFAVCDIPTGTELTFNYNLDCLGNEKTVCRCGAPNCSGFLGDRPKIAPTSESKSKPQKKKPRKRRARSEG------KKQSEDECFRCGDGGQL---VLCDKKGCTKAYHLSCLDRTKRPF--GRWDCPWHHCDVCGKPSDAFCQHCPNSFC 1317
BLAST of NSD-1 vs. Ensembl Cavefish
Match: nsd2 (nuclear receptor binding SET domain protein 2 [Source:ZFIN;Acc:ZDB-GENE-030131-2581]) HSP 1 Score: 393.66 bits (1010), Expect = 2.209e-117 Identity = 241/698 (34.53%), Postives = 342/698 (49.00%), Query Frame = 3
Query: 693 CRYCLET-KNIVQCNKCLFNNFHVKCLEFLQNSIETKINDLDRCLECSLGIIRCYACYKIVDISNEQGFMRCIIKTCTKWFHTNCLETGPMLEMTKFPKPGQLVCPCHICHKCELVN-PSPKYRCTKLIVCIMCPATFHTGDWCIPAGSVELNTGEIICPRHL-VDLNFSMNIMVPPFVARVKSDLQERIYGNTLTKISEPMTITPSTVTKPTNVNWCFKCGEGGELLCCETCPAAYHFKCTDLKEIPQKFYCPDCASFCYRSYGEIVWIKCGTHPWWPGQILHLENVPKNIAAKKHANGQFVVQFFGSRDYMWRDHGNVFLYEKEDECNSKTSKYRYNNIFLEGIKEAAIGYVT-REEKWQSGSCDHVMNSKIYNKIQVNK--CPLELRRKVVPETPHCNCISFDPKSDCSIGSGCFNVASKCECDPQICNLGDKCKNQNFVKRIYPKQYTFWANDRGWGLKADEFIKTKQFVNEYIGEIITMEESEKRILWANENNITDFYFMELDNGRLIDARQFSNLSRFINNSCDPNLVAEKWIVNREHRIGLFALRDIQKGEELTFQYNLQNKSSNRIVCKCFSVNCSGFLGEAPKMAXXXXXXXXXXXXXXXXXXXXXXXCKSFLTDKNSNSQCFRCGEIIDMLSSIVCSVGPCMKTYHSVCLNLNMANYVQSSWICPHHYCDVCARPSHHFSSNTTESYC 2768
C+ C +T +++V C F +H++CL + D C C G+ C+ C + +E RC + C K++H CL + +T F G CP H C C N + K K+I C+ CP +H GD C+ AGS L + I+C H +S + V NV+WCF C +GG LLCCE+CPAA+H C ++ ++C DC S Y +I+W+K G + WWP +I H N+P NI +H G+F V FFGS+DY W G VF Y + D S+ + +F + EA + + E+ + ++ Y I+ NK +++ + E P CNC D + CS S C N EC PQ+C G++C NQ+F KR+YP+ T +GWGL IK +FVNEY+GE+I EE RI +A EN+IT FY + ++ R+IDA N SRF+N+SC PN +KW VN + R+GLFA+ DI G ELTF YNL + + VC+C + NCSGFLG+ PK+A S+ KS KK K S +CFRCG+ + ++C C K YH CL+ + W CP H+CDVC +PS F + S+C
Sbjct: 733 CQVCEKTSEDLVTCEGHCFATYHLQCLGLDHPT------DKVLCTACRTGVHACFTCKQ-----SEGEVKRCSVLHCGKYYHEACLR---LSALTVFDNRG-FRCPLHTCLSCHYSNRGTAKATKGKMIRCLRCPVAYHAGDLCVAAGSEMLTSTAIVCTNHFNPKKGYSHHSHV--------------------------------------NVSWCFICSKGGRLLCCESCPAAFHPDCLNIAMPDGSWFCNDCRSGKKPKYRDIIWVKLGNYRWWPAEIRHPRNIPTNIQHLRHEIGEFPVYFFGSKDYFWTHQGRVFPYIEGDR-GSRHQRNGIGKVFKTALLEAETRFKQIKMEREAKEAHENNKKPPPYKYIKTNKPCGRVQIYTADISEIPKCNCKPTDERP-CSFESECLNRMLLYECHPQVCPAGERCMNQDFTKRLYPETKTIRTAGKGWGLLTLRDIKKGEFVNEYVGELIDEEECRARIRYAQENDITHFYMLTINKDRIIDAGPKGNYSRFMNHSCQPNCETQKWTVNGDTRVGLFAVCDIPTGTELTFNYNLDCLGNEKTVCRCGAPNCSGFLGDRPKIAPTSESKSKPQKKKPRKRRARSEG------KKQSEDECFRCGDGGQL---VLCDKKGCTKAYHLSCLDRTKRPF--GRWDCPWHHCDVCGKPSDAFCQHCPNSFC 1364
BLAST of NSD-1 vs. Ensembl Cavefish
Match: nsd1a (nuclear receptor binding SET domain protein 1a [Source:ZFIN;Acc:ZDB-GENE-080519-3]) HSP 1 Score: 382.489 bits (981), Expect = 5.021e-112 Identity = 245/726 (33.75%), Postives = 357/726 (49.17%), Query Frame = 3
Query: 669 SVKLTNKNCRYCLETKNIVQCNKCLFNNFHVKCLEFLQNSIETKINDLDR----CLECSLGIIRCYACYKIVDISNEQGFMRCIIKTCTKWFHTNCLETGPMLEMTKFPKPGQLVCPCHICHKCELVNPS-PKYRCTKLIVCIMCPATFHTGDWCIPAGSVELNTGEIICPRHLVDLNFSMNIMVPPFVARVKSDLQERIYGNTLTKISEPMTITPSTVTKPTNVNWCFKCGEGGELLCCETCPAAYHFKCTDLKEIPQ-KFYCPDCASFCYRSYGEIVWIKCGTHPWWPGQILHLENVPKNIAAKKHANGQFVVQFFGSRDYMWRDHGNVFLYEKEDECNSKTSKYRYNNIFLEGIKEAAIGY--VTREEKWQSGSCDHVMNSKI--YNKIQVNK--CPLELRRKVVPETPHCNCISFDPKSDCSIGSGCFNVASKCECDPQICNLGDKCKNQNFVKRIYPKQYTFWANDRGWGLKADEFIKTKQFVNEYIGEIITMEESEKRILWANENNITDFYFMELDNGRLIDARQFSNLSRFINNSCDPNLVAEKWIVNREHRIGLFALRDIQKGEELTFQYNLQNKSSNRIVCKCFSVNCSGFLGEAPKMAXXXXXXXXXXXXXXXXXXXXXXXCKSFLTDKNSNSQCFRCGEIIDMLSSIVCSVGPCMKTYHSVCLNLNMANYVQSSWICPHHYCDVCARPSHHFSSNTTESYCNKD-----FIKKFN 2795
+ L C+ C + ++ C FH++C+ ++++ R C EC G+ C+ C +S E RC++ C K++H C+ + P+ C H+C C + NP+ P +L C+ CP +H D+C+ AGSV L I+CP H F R E I NV+WCF C EGG LLCCE+CPAA+H +C ++ E+PQ +YC DC + Y +I+W+K G + WWP ++ +NVP+NI KH G+F V FFGS+DY+W F Y + D N + + ++ + + EAA + + E++ + D + K Y I+VN+ +++ + E P CNC + D ++ C + S C N EC+PQ+C G++C+NQ F KR Y F RGWGL++ IK FV+EY+GE+I EE RI A +N+I++FY + LD R+IDA N +RF+N+ C PN +KW VN + R+GLFAL DI G ELTF YNL+ + + VCKC + NCSGFLG PK S+ K KK +S+S K +CF CG+ ++S C C K YH+ CLNLN W CP H C+ C R + F SYC + FI K +
Sbjct: 1201 AASLKENVCQVCEQPGELLLCEGHCCGAFHLQCI---------GLSEMPRGRFVCKECKSGLHTCFVC----KLSGED-VRRCMVPVCGKFYHAECI----LKYAPTAPQNRGFRCSLHVCLACYITNPNNPSISKGRLTRCVRCPVAYHANDYCMAAGSVPLANNSILCPNH--------------FTPRKGCKNHEHI-----------------------NVSWCFVCSEGGSLLCCESCPAAFHRECLNI-EMPQDSWYCNDCRAGKKPQYKDILWVKVGRYRWWPAEVTLPKNVPENILRMKHEVGEFPVHFFGSKDYVWTYQARCFPYMEGDASNIEKMGKGTDAVYKKALNEAAERFRELQAEKEMRQLQEDRKNDKKPPPYKHIKVNRPIGKVQILTADLSEIPRCNCKATD-ETPCGMDSECINRMLMYECNPQVCAAGERCQNQCFTKREYSPVEIFRTLSRGWGLRSVSEIKKGAFVSEYVGEMIDEEECRARIKHAQDNDISNFYMLTLDKDRIIDAGPKGNEARFMNHCCQPNCETQKWTVNGDTRVGLFALEDIGAGVELTFNYNLECLGNGKTVCKCGAPNCSGFLGVRPKNQPPSEDKGRKLKKRVSGKRKSQSE-----VIKEREDECFYCGDSGQIIS---CKKPGCPKVYHADCLNLN--KRPAGRWECPWHQCNECGREAASFCEMCPNSYCKQHRDGMLFISKLD 1859
BLAST of NSD-1 vs. Ensembl Cavefish
Match: nsd1b (nuclear receptor binding SET domain protein 1b [Source:ZFIN;Acc:ZDB-GENE-080519-2]) HSP 1 Score: 353.599 bits (906), Expect = 8.850e-110 Identity = 210/574 (36.59%), Postives = 295/574 (51.39%), Query Frame = 3
Query: 1065 KLIVCIMCPATFHTGDWCIPAGSVELNTGEIICPRHLVDLNFSMNIMVPPFVARVKSDLQERIYGNTLTKISEPMTITPSTVTKPTNVNWCFKCGEGGELLCCETCPAAYHFKCTDLKEIPQKFYCPDCASFCYRSYGEIVWIKCGTHPWWPGQILHLENVPKNIAAKKHANGQFVVQFFGSRDYMWRDHGNVFLYEKEDECNSKTSKYRYNNIFLEGIKEAAIGY--VTREEKWQSGSCDHVMNSKI--YNKIQVNK--CPLELRRKVVPETPHCNCISFDPKSDCSIGSGCFNVASKCECDPQICNLGDKCKNQNFVKRIYPKQYTFWANDRGWGLKADEFIKTKQFVNEYIGEIITMEESEKRILWANENNITDFYFMELDNGRLIDARQFSNLSRFINNSCDPNLVAEKWIVNREHRIGLFALRDIQKGEELTFQYNLQNKSSNRIVCKCFSVNCSGFLGEAPKMAXXXXXXXXXXXXXXXXXXXXXXXCKSFLTDKNSNSQCFRCGEIIDMLSSIVCSVGPCMKTYHSVCLNLNMANYVQSSWICPHHYCDVCARPSHHFSSNTTESYC 2768
+L C+ CP +H D+CIPAGSV L I+CP H F+ R E + NV+WCF C EGG LLCCE+CPAA+H +C ++ ++C DC + Y E+VW+K G + WWP ++ + +N+P+NI +H G+F V FFGS DY+W VF Y + D + + ++++ + ++EAA + + E++ + D + K Y I+ N+ +++ + E P CNC + D +S C + S C N EC+PQ+C G+KC+NQ F+KR Y + F RGWGL+ IK FVNEY+GE+I EE RI A EN+I +FY + LD R+IDA N +RF+N+SC PN +KW VN + R+GLFAL DI G ELTF YNL+ + + VCKC + NCSGFLG PK S K +K + + K +CF CG+ M+S C C K YH+ CLNL W CP H CD+C + S F SYC
Sbjct: 14 RLTRCVRCPIAYHATDYCIPAGSVILANNLILCPNH--------------FIPRKGCRNHEHV-----------------------NVSWCFVCSEGGSLLCCESCPAAFHRECLNIDMPEGSWFCNDCRAGKKPHYKEVVWVKVGRYRWWPAEVSNPKNIPENILRMRHDVGEFPVLFFGSNDYLWTYQARVFPYMEGDANSKEKMGKGVDSVYKKALEEAAKRFQELQAEKELRQLQEDRRNDKKPPPYKHIKANRPIGKVQIITADLSEIPRCNCRATD-ESPCGMDSECINRMLLYECNPQVCPAGEKCQNQRFLKREYSEVEIFRTLSRGWGLRGCHDIKKGDFVNEYVGEVIDEEECRARIRQAQENDIGNFYMLTLDKDRIIDAGPKGNEARFMNHSCQPNCETQKWTVNGDTRVGLFALVDISTGTELTFNYNLECLGNGKTVCKCGAPNCSGFLGVRPKNNPPSDDKGRKKRKGYMKRKQQQE------VTKEREDECFSCGDGGQMVS---CKRPGCPKVYHADCLNL--TKRPAGRWECPWHQCDLCGQESASFCEMCPSSYC 538
BLAST of NSD-1 vs. Ensembl Cavefish
Match: nsd3 (nuclear receptor binding SET domain protein 3 [Source:ZFIN;Acc:ZDB-GENE-050324-2]) HSP 1 Score: 305.834 bits (782), Expect = 4.105e-87 Identity = 191/504 (37.90%), Postives = 260/504 (51.59%), Query Frame = 3
Query: 1284 PMTITPSTVTKPTNVNWCFKCGEGGELLCCETCPAAYHFKCTDLKEIPQKFY-CPDCASFCYRSYGEIVWIKCGTHPWWPGQILHLENVPKNIAAKKHANGQFVVQFFGSRDYMWRDHGNVFLYEKEDECNSKTSKYRYNNIFLEGIKEAAIGY----VTREEKWQSGSCDHVMNSKIYNKIQVNKCPLELRRKV--VPETPHCNCISFDPKSDCSIGSGCFNVASKCECDPQICNLGDKCKNQNFVKRIYPKQYTFWANDRGWGLKADEFIKTKQFVNEYIGEIITMEESEKRILWANENNITDFYFMELDNGRLIDARQFSNLSRFINNSCDPNLVAEKWIVNREHRIGLFALRDIQKGEELTFQYNLQNKSSNRIVCKCFSVNCSGFLGEAPKMAXXXXXXXXXXXXXXXXXXXXXXXCKSFLTDKNSNSQCFRCGEIIDMLSSIVCSVGPCMKTYHSVCLNLNMANYVQSSWICPHHYCDVCARPSHHFSSNTTESYCNK 2774
PM + S+ TK NV G+GG LLCCE CPA++H C ++ E+P+ + C +C + Y +IVW+K G + WWP +I + VP NI + KH G F V FFGS DY W G VF Y + D+ N + N F + ++EAA + RE K + Y I+ NK +++ V + E P CNC D + C S C N + EC PQ+C ++C NQ+F KR+YP + RGWGLK + +K F+ EY+GE+I +EE +RI AN+N+IT+FY + L R+IDA NLSRF+N+SC PN +KW VN + RIGLF L DI ELTF YNL + R C C + NCSGFLG PK A V + + + + CF CGE ++ ++C C K YH +CLNL Y W CP H C VC RP+ ES+C +
Sbjct: 743 PMIPSSSSATK-KNV------GKGGRLLCCEACPASFHPSCLNI-EMPEGVWLCSECRAGKKPHYKQIVWVKLGNYRWWPAEICNPRLVPSNIQSLKHDVGDFPVFFFGSHDYYWIHQGRVFPYVESDK-NFAEGQVGINKTFKKALEEAAKRFQELKAQRETKEALEQERNSRRPPPYKLIKANKPVGKVQVHVADLSEVPRCNCRPTDERP-CGQDSQCLNRMLQYECHPQVCPAAERCLNQSFSKRVYPDTEVIKTSGRGWGLKTKQDLKKGDFIMEYVGELIDLEECRQRISHANKNHITNFYMLTLTKDRVIDAGPKGNLSRFMNHSCSPNCETQKWTVNGDIRIGLFTLCDIAADTELTFNYNLDCLGNGRTSCHCGAENCSGFLGVRPKSAVVMEREEKVKNSKLKAKKRK----LKLESRQTHEYYCFCCGEGGEL---VMCDRKDCPKAYHLLCLNLTKPPY--GRWECPWHQCSVCQRPASASCQFCPESFCRE 1227
BLAST of NSD-1 vs. Ensembl Sea Lamprey
Match: nsd2 (nuclear receptor binding SET domain protein 2 [Source:ZFIN;Acc:ZDB-GENE-030131-2581]) HSP 1 Score: 375.555 bits (963), Expect = 1.614e-112 Identity = 240/696 (34.48%), Postives = 344/696 (49.43%), Query Frame = 3
Query: 717 NIVQCNKCLFNNFHVKCLEFLQNSIETKINDLDRCLECSLGIIRCYACYKIVDISNEQGFMRCIIKTCTKWFHTNCLE--TGPMLEMTKFPKPGQLVCPCHICHKCELVNP-SPKYRCTKLIVCIMCPATFHTGDWCIPAGSVELNTGEIICPRHL----------VDLNF----SMNIMVPPFV-ARVKSDLQERIYGNTLTKISEPMTITPSTVTKPTNVNWCFKCGEGGELLCCETCPAAYHFKCTDLKEIPQKFYCPDCASFCYRSYGEIVWIKCGTHPWWPGQILHLENVPKNIAAKKHANGQFVVQFFGSRDYMWRDHGNVFLYEKEDECNSKTSKYRYNNIFLEGIKEAAIGYVTREEKWQSGSCDHVMNSK----IYNKIQVNK--CPLELRRKVVPETPHCNCISFDPKSDCSIGSGCFNVASKCECDPQICNLGDKCKNQNFVKRIYPKQYTFWANDRGWGLKADEFIKTKQFVNEYIGEIITMEESEKRILWANENNITDFYFMELDNGRLIDARQFSNLSRFINNSCDPNLVAEKWIVNREHRIGLFALRDIQKGEELTFQYNLQNKSSNRIVCKCFSVNCSGFLGEAPKMAXXXXXXXXXXXXXXXXXXXXXXXCKSFLTDKNSNSQCFRCGEIIDMLSSIVCSVGPCMKTYHSVCLNLNMANYVQSSWICPHHYCDVCARPS 2732
++V C FHV+CL ++T D C ECS G+ C+AC K RC + +C +++H C++ + + E +F CP H+C C L P S + ++ C+ CP +HT D C+ AGS L+ I+C H V++N+ S ++ P A + Q Y + K S + P P CG+GG LLCCE+CPAA+H +C ++ + C +C + Y +IVW+K G + WWP +I N+P+NI KH GQF VQFFGS DY W G VF Y + D+ ++ N F + EAA Y + + ++ S+ Y I+ NK +++ V E P CNC D +S C + S C N + EC P IC GD+C+NQ F KR YP RGWGL I+ +FVNEY+GE+I EE KRI +A+E N+++FY + ++ R+IDA N SRF+N+SC PN +KW VN + R+GLFA DI G ELTF YNL + + +CKC + NCSGFLG PK A + + K + ++ +C+RCG+ ++ ++C C K YH CLNL + W CP H+CDVC RPS
Sbjct: 579 SLVSCEGQCCGTFHVECL-----GVQTAPGDKVMCNECSTGLHVCFAC-KCAGAE----VRRCAVSSCGRFYHEECVQRSSAAVFEGRRF------RCPLHVCLSCHLAYPASSRASRGRMQRCVRCPVAYHTSDSCLAAGSKVLSPYSIVCSGHFTPNKRDSTWHVNVNWCFLCSRGVIGAPLPDAGLALFEQSSHYLLSEYKRSSELGKLPMIPVVPAAAA--KACGKGGCLLCCESCPAAFHPECLGMEPPEGTWCCAECRAGKKPQYHDIVWVKLGNYRWWPAEICQPRNIPQNIQNLKHTVGQFPVQFFGSHDYYWTTQGRVFPYMEGDKGSTDYKTNCLNKTFKRALLEAAARYQALKAQRETREAQETERSERKPPTYKHIKSNKPVGRVQVYTADVSEIPRCNCKPTD-ESPCGLDSECLNRMLQYECHPSICPAGDRCQNQAFTKRAYPPSQIVKTAGRGWGLLTLVSIRKGEFVNEYVGELIDEEECRKRIKYAHEKNLSNFYMLTIEKDRIIDAGPKGNFSRFMNHSCQPNCETQKWTVNGDTRVGLFATSDIATGTELTFNYNLDCLGNEKTICKCGAPNCSGFLGVRPKTAAAAATEEKAKKAKRKARGRRP---RTETARAEHEDECYRCGDGGEL---VMCDKKACPKAYHLSCLNLTKPPF--GKWECPWHHCDVCGRPS 1247
BLAST of NSD-1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000003690.1 (pep scaffold:Pmarinus_7.0:GL484755:705:3732:1 gene:ENSPMAG00000003373.1 transcript:ENSPMAT00000003690.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 104.76 bits (260), Expect = 3.491e-25 Identity = 62/154 (40.26%), Postives = 83/154 (53.90%), Query Frame = 3
Query: 2205 RLIDARQFSNLSRFINNSCDPNLVAEKWIVNREHRIGLFALRDIQKGEELTFQYNLQNKSSNRIVCKCFSVNCSGFLGEAPKMAXXXXXXXXXXXXXXXXXXXXXXXCKSFLTDKNSNSQCFRCGEIIDMLSSIVCSVGPCMKTYHSVCLNLNM 2666
R+IDA N SRF+N+SC PN +KW VN + R+GLFA+ DI G ELTF YNL + + VC C + NCSGFLG PK + D K K + DK +S+C+RC + ++ ++C C KT+H CLNL
Sbjct: 3 RIIDAGPKGNFSRFMNHSCQPNCETQKWTVNGDTRVGLFAVSDIPCGTELTFNYNLDCLGNEKTVCMCGAPNCSGFLGVRPKRVRAQSAVVDKKPKRKYRK-------RKVRADKVHDSECYRCKDGGEL---VMCDHRNCTKTFHLACLNLGT 146
BLAST of NSD-1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000005461.1 (pep scaffold:Pmarinus_7.0:GL477205:1717:42601:-1 gene:ENSPMAG00000004962.1 transcript:ENSPMAT00000005461.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 110.923 bits (276), Expect = 5.936e-25 Identity = 67/221 (30.32%), Postives = 107/221 (48.42%), Query Frame = 3
Query: 1800 IYNKIQVNKCPLELRRKVVPETPHCNCISFDPKSDCSIGSGCFNVASKCECDPQICNLGDKCKNQNFVKRIYPKQY-TFWANDRGWGLKADEFIKTKQFVNEYIGEIITMEE----SEKRILWANENNITDFYFMELDNGRLIDARQFSNLSRFINNSCDPNLVAEKW--IVNREHRIGLFALRDIQKGEELTFQYNLQN-KSSNRIVCKCFSVNCSGFLG 2438
+Y KI+ ++++ E C+C + D + GC N EC C G+ C N+ F ++ F DRGWG++ + + EY+GE+++ + + + A Y ++LD+G +ID+ + N +RFIN+SC PN +KW VN +RIGLFAL+DI ELT+ YN + ++ C C S NC +G
Sbjct: 1093 LYKKIRSTDVFVDMKPLSGCEPVSCSCKRPEETEDSACTEGCLNRLVYAECVQSSCPCGELCTNRRFQRQERSAGLERFRTTDRGWGVRTTHHFQANDLIIEYLGEVLSEANFRAFAPRSRMLAQRGEQAGMYCVQLDSGVVIDSYRMGNEARFINHSCQPNCEMQKWCVSVNGIYRIGLFALKDIPISTELTYDYNFHTFTAESQRPCLCGSPNCRNVIG 1313
BLAST of NSD-1 vs. Ensembl Sea Lamprey
Match: SUV39H2 (suppressor of variegation 3-9 homolog 2 [Source:HGNC Symbol;Acc:HGNC:17287]) HSP 1 Score: 102.449 bits (254), Expect = 3.324e-23 Identity = 68/193 (35.23%), Postives = 97/193 (50.26%), Query Frame = 3
Query: 1947 ECDPQICNLGDKCKNQNFVKRI-YPKQYTFWANDRGWGLKADEFIKTKQFVNEYIGEIITMEESEKRILWANENNITDFYFMELD---NGRLIDARQFSNLSRFINNSCDPNLVAEKWIVN----REHRIGLFALRDIQKGEELTFQYNLQNKSSN----------------------RIVCKCFSVNCSGFL 2435
EC+ +C G +CKN+ K I +P N RGWG+K + IK FV EY+GE+I EE+E+R + + T Y +LD + +DA + N+S F+N+SC+PNL +N + RI FA+ D+ GEELTF YN+++ SS RI CKC + C FL
Sbjct: 231 ECN-SLCQCGPECKNRVVQKGIPFPLCIFRTDNGRGWGVKTMQKIKKNSFVMEYVGELIPSEEAERRGVIYDRAGTT--YLFDLDFCKDDYTVDATFYGNISHFVNHSCEPNLQVYSTFINNHDFSQPRIAFFAMDDLAAGEELTFDYNIKDSSSQNESCNKDTVLHTTVTTSPKQRARITCKCGASTCRKFL 420
BLAST of NSD-1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004922.1 (pep scaffold:Pmarinus_7.0:GL479351:23010:32607:-1 gene:ENSPMAG00000004401.1 transcript:ENSPMAT00000004922.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 87.0409 bits (214), Expect = 1.087e-17 Identity = 56/165 (33.94%), Postives = 83/165 (50.30%), Query Frame = 3
Query: 1947 ECDP---QICNLGDKCKNQNF------VKRIYPKQYTFWAND-RGWGLKADEFIKTKQFVNEYIGEIITMEESEKRILWANENNITDFY----FMELDNGRLIDARQFSNLSRFINNSCDPNLVAEKWIVNREHRIGLFALRDIQKGEELTFQYNLQNKSSNRIV 2399
ECDP Q C D N+N ++R K +D GWG+ ++ +F++EY GEII+ +E+++R + D Y L+N ++DA + N RF N+S PN A+ +VN +HRIG+FA R IQ GEEL F Y + + V
Sbjct: 616 ECDPDLCQTCGAADHWDNRNVSCKNCCIQRGLKKHLLLAPSDVAGWGIFIKVPVQKNEFISEYCGEIISQDEADRR------GKVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSVSPNCYAKVMMVNGDHRIGIFAKRAIQTGEELFFDYRYSQADALKYV 774
BLAST of NSD-1 vs. Ensembl Yeast
Match: SET2 (Histone methyltransferase with a role in transcriptional elongation; methylates H3 lysine 36 (H3K36), which suppresses incorporation of acetylated histones and signals for the deacetylation of these histones within transcribed genes; associates with the C-terminal domain(CTD) of Rpo21p; H3K36me3 (trimethylation) requires Spt6p, proline 38 on H3, CTD of Rpo21p, Ctk1p, and C-terminal SRI domain of Ste2p; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000003704]) HSP 1 Score: 134.035 bits (336), Expect = 1.369e-32 Identity = 71/179 (39.66%), Postives = 101/179 (56.42%), Query Frame = 3
Query: 1905 CSIGSGCFNVASKCECDPQICNL-GDKCKNQNFVKRIYPKQYTFWANDRGWGLKADEFIKTKQFVNEYIGEIITMEESEKRILWANENNITDFYFMELDNGRLIDARQFSNLSRFINNSCDPNLVAEKWIVNREHRIGLFALRDIQKGEELTFQYNLQNKSSNRIVCKCFSVNCSGFLG 2438
C S C N + EC +C+ G+ C+NQ F K+ Y F +G+G++A++ I+ QF+ EY GE+I E R++ ++ + FYFM L NG IDA +L+RF N+SC PN KW+V + R+G+FA R I KGEE+TF YN+ + C C NC GFLG
Sbjct: 82 CDEDSDCINRLTLIECVNDLCSSCGNDCQNQRFQKKQYAPIAIFKTKHKGYGVRAEQDIEANQFIYEYKGEVIEEMEFRDRLIDYDQRHFKHFYFMMLQNGEFIDATIKGSLARFCNHSCSPNAYVNKWVVKDKLRMGIFAQRKILKGEEITFDYNVDRYGAQAQKCYCEEPNCIGFLG 260
BLAST of NSD-1 vs. Ensembl Yeast
Match: SET1 (Histone methyltransferase, subunit of the COMPASS (Set1C) complex; COMPASS methylates histone H3K4; Set1p-dependent H3K4 trimethylation recruits Nrd1p, allowing efficient termination of snoRNAs and cryptic unstable transcripts (CUTs) by Nrd1p-Nab3p-Sen1p pathway; modulates histone acetylation levels in promoter proximal regions to ensure efficient Nrd1p-dependent termination; required in transcriptional silencing near telomeres and at silent mating type loci; has a SET domain [Source:SGD;Acc:S000001161]) HSP 1 Score: 90.5077 bits (223), Expect = 7.519e-19 Identity = 50/130 (38.46%), Postives = 71/130 (54.62%), Query Frame = 3
Query: 2052 WGLKADEFIKTKQFVNEYIGEIITMEESEKRILWANENNITDFYFMELDNGRLIDARQFSNLSRFINNSCDPNLVAEKWIVNREHRIGLFALRDIQKGEELTFQYNLQNKSSN--RIVCKCFSVNCSGFL 2435
WGL A + I K+ + EY+GE I +E R +N I Y +D +IDA + ++RFIN+ CDPN A+ V RI ++ALRDI EELT+ Y + + + R+ C C + NC GFL
Sbjct: 950 WGLYALDSIAAKEMIIEYVGERIRQPVAEMREKRYLKNGIGSSYLFRVDENTVIDATKKGGIARFINHCCDPNCTAKIIKVGGRRRIVIYALRDIAASEELTYDYKFEREKDDEERLPCLCGAPNCKGFL 1079
BLAST of NSD-1 vs. Ensembl Nematostella
Match: EDO43156 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RZJ4]) HSP 1 Score: 336.65 bits (862), Expect = 6.299e-103 Identity = 216/667 (32.38%), Postives = 310/667 (46.48%), Query Frame = 3
Query: 816 RCLECSLGIIRCYACYKIVDISNEQGFMRCIIKTCTKWFHTNCLETGPMLEMTKFPKPGQLVCPCHICHKCELVNPSPKYRCTKLIVCIMCPATFHTGDWCIPAGSVELNTGEIICPRHLVDLNFSMNIMVPPFVARVKSDLQERIYGNTLTKISEPMTITPSTVTKPTNVNWCFKCGEGGELLCCETCPAAYHFKCTDLKEIPQ-KFYCPDCASFCYRSYGEIVWIKCGTHPWWPGQILHLENVPKNIAAKKHANGQFVVQFFGSRDYMWRDHGNVFLYEKEDECNSKTSKYRYNNIFLEGIKEAAIGY----VTREEKWQSGSCDHVMNSKIYNKIQVNKCPLELRRKVVP-ETPHCNCISFDPKSDCSIGSGCFNVASKCECDPQICNLGDKCKNQNFVKRIYPKQYTFWANDRGWGLKADEFIKTKQFVNEYIGEIITMEESEKRILWANENNITDFYFMELDNGRLIDARQFSNLSRFINNSCDPNLVAEKWIVNREHRIGLFALRDIQKGEELTFQYNLQNKSSNRIVCKCFSVNCSGFLGEAPKMAXXXXXXXXXXXXXXXXXXXXXXXCKSFLTDKNSNSQCFRCGEIIDMLSSIVCSVGPCMKTYHSVCLNLNMANYVQSSWICPHHYCDVCARPSHHFSSNTTESYCNKDFIKKFNS 2798
+C EC+ G+ C+ C + D+ C C+K++H CL++ ++ ++ CP H C C + N +P R +L CI CP +H G C+ AG + + + ++C +H + P ++ NVNWCF C GG L+CCE+CPAA+H +C + IP+ +FYC DC YG+IVW+K G + WWP I + +VP NI + +H G+F V F GS D+ W G VF Y+ D+ + +F + + EA Y RE+K + Y I+ NKC R + P E P C C P C + C N+ + EC C GDKC+NQ F KR Y F A+ RGWGL++ + IK FV EY+GE+I +R+ +++ T++Y + +D +IDA NLSRF+N+SC PN +KW VN E R+GLF RD++ EELTF Y L + + C C S NCSGFLG PK + + K + CF CG D I+C C+K YH CLNL+ Q W CP H+CD C + + S S+C + NS
Sbjct: 26 KCDECTSGVHSCFVCRQTGDVK------ACSQPLCSKFYHKECLQSYKCSKIDG----DRIYCPLHFCSTC-ISNKTPVNR-GRLTKCIRCPTAYHAG--CLVAGCMPITSHLMVCAKHFL-----------PNKSKAHH--------------------------THVNVNWCFVCSIGGTLICCESCPAAFHPECISYEGIPEGRFYCKDCVEGKSLLYGDIVWVKLGMYRWWPAMICNPRDVPTNIQSMRHQPGEFPVMFLGSHDFYWIHKGRVFSYQDGDKGTESGNNKYLAKVFKKALVEAKEKYDEWKKAREDKAEQDLQRFCKKPPQYKHIKTNKCTTAQRIILDPSEMPVCECT---PDQACGQDANCLNLMLQFECVASRCPAGDKCQNQRFQKRQYVDCEPFRAHSRGWGLRSKQAIKKGTFVIEYVGELIDDATCRERVKKGDDD--TNYYMLTIDKDCIIDAGPMGNLSRFMNHSCYPNCETQKWTVNGEVRVGLFTSRDVESQEELTFDYCLDCHGNEKKKCHCGSQNCSGFLGVRPKTQNAQMNEDKAKNAALKRRKRKP---KKPAVKQVHEDDCFICG---DGGQLIMCDRSGCLKCYHVDCLNLDKK--PQGRWQCPWHFCDNCGKRATVLCSECPNSFCRSHAQGQINS 628
BLAST of NSD-1 vs. Ensembl Nematostella
Match: EDO43763 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RXE9]) HSP 1 Score: 124.02 bits (310), Expect = 1.088e-30 Identity = 69/175 (39.43%), Postives = 92/175 (52.57%), Query Frame = 3
Query: 1914 GSGCFNVASKCECDPQICNLGDKCKNQNFVKRIYPKQYTFWANDRGWGLKADEFIKTKQFVNEYIGEIITMEESEKRILWANENNITDFYFMELDNGRLIDARQFSNLSRFINNSCDPNLVAEKWIVNREHRIGLFALRDIQKGEELTFQYNLQNKSSNRIVCKCFSVNCSGFLG 2438
G C N EC+ + C GD C N+ F + K F +GWG+K E ++ QFV EY GE++ + + R + +YFM L +IDA ++SRFIN+SC+PN V +KW VN RIG F LR I+ GEELTF Y LQ C C S +C G +G
Sbjct: 44 GEDCLNRLLMIECNHR-CPCGDLCTNRRFQEGCKIKVEVFKTEKKGWGVKTLEDLEQNQFVIEYCGEVMNYRDFQSRAQRYDRQKRRHYYFMTLRADEIIDATLKGSISRFINHSCEPNCVTQKWTVNGLLRIGFFTLRTIKAGEELTFDYQLQRYGKIAQTCYCESPSCRGIIG 217
BLAST of NSD-1 vs. Ensembl Nematostella
Match: EDO36231 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SJ88]) HSP 1 Score: 90.8929 bits (224), Expect = 2.699e-20 Identity = 67/186 (36.02%), Postives = 97/186 (52.15%), Query Frame = 3
Query: 1872 CNCISFDPKS-DCSIGSG---CFNVASKCECDP--------QICNLGDKCKNQNFVKRIYPKQYTFWA--NDRGWGLKADEFIKTKQFVNEYIGEIITMEESEKR---ILWANENNITDFYFMELDNGRLIDARQFSNLSRFINNSCDPNL-VAEKWIVNRE---HRIGLFALRDIQKGEELTFQY 2366
CNC PKS +C SG ++ + + +P C+ + C+N+ V+R + T + N GWG+K + I QFV EY+GE+IT EE+E R A + + D + + D IDA+++ N+S FIN+SCDPNL V W+ + RI FA RDI GEE+TF Y
Sbjct: 58 CNCQRCTPKSCECPKNSGGVFAYDRFGRVQFEPGKPIYECNSKCSCSESCRNR-VVQRGRTVRVTIFRTYNGCGWGVKTMDPIMKNQFVTEYVGEVITNEEAEHRGRHYDAAGQTYLFDLDYNDGDCAYTIDAKKYGNISHFINHSCDPNLSVFGVWVDTLDPQMPRIAFFARRDIPAGEEITFDY 242
BLAST of NSD-1 vs. Ensembl Nematostella
Match: EDO49808 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RFZ3]) HSP 1 Score: 84.3445 bits (207), Expect = 4.792e-18 Identity = 60/179 (33.52%), Postives = 89/179 (49.72%), Query Frame = 3
Query: 1947 ECDPQICNLGDKCKNQNFVKRIYPKQYTFWANDRGWGLKADEFIKTKQFVNEYIGEIITMEESEKRILWA-NENNITDFYFMELDNGRL----IDARQFSNLSRFINNSCDPNLVAEKWIVNRE-HRIGLFALRDIQKGEELTFQYN-----LQNKSSNR-----IVCKCFSVNCSGFL 2435
EC+ Q CN C + K I + F + + WGL+ E I QF+ EY GE+++ +E++KR + N + G++ +D R + N RFIN+SCDPNLV V+ ++ LFA +DI EEL+F Y+ L + S + C C S NC+GFL
Sbjct: 66 ECNSQ-CNCDLSCYTKLVQKLIQTRLEVFKSKHKLWGLRTLEHISQGQFICEYAGEVLSYKEAKKRTIEGKGRPNYIITVKEHISGGKILRTHVDPRIYGNAGRFINHSCDPNLVMVPVRVDSLIPKLALFASKDIFPNEELSFDYSGGRCGLPSSSCADDPALCLPCYCNSSNCTGFL 243
BLAST of NSD-1 vs. Ensembl Nematostella
Match: EDO30322 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T142]) HSP 1 Score: 88.1965 bits (217), Expect = 6.720e-18 Identity = 55/165 (33.33%), Postives = 85/165 (51.52%), Query Frame = 3
Query: 1947 ECDPQICNL---------GDKCKNQNFVKRIYPKQYTFWAND-RGWGLKADEFIKTKQFVNEYIGEIITMEESEKRILWANENNITDFY----FMELDNGRLIDARQFSNLSRFINNSCDPNLVAEKWIVNREHRIGLFALRDIQKGEELTFQYNLQNKSSNRIV 2399
ECDP +C CKN + ++R K +D GWG+ + +K +F++EY GE+I+ +E+++R + D Y L+N ++DA + N RF N+S PN A+ +VN +HRIG+FA RDI+ GEEL F Y + + V
Sbjct: 520 ECDPDLCGTCGADNFDQDSKTCKNVS-LQRGQRKHMLLAPSDVAGWGIYIKQSVKKNEFISEYCGEVISQDEADRR------GKVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSISPNCYAKVMMVNGDHRIGIFAKRDIEAGEELFFDYRYSATDALKFV 677
BLAST of NSD-1 vs. Ensembl Medaka
Match: nsd2 (nuclear receptor binding SET domain protein 2 [Source:NCBI gene;Acc:101172132]) HSP 1 Score: 391.734 bits (1005), Expect = 1.202e-117 Identity = 243/699 (34.76%), Postives = 341/699 (48.78%), Query Frame = 3
Query: 693 CRYCLET-KNIVQCNKCLFNNFHVKCLEFLQNSIETKINDLDRCLECSLGIIRCYACYKIVDISNEQGFMRCIIKTCTKWFHTNCLETGPMLEMTKFPKPGQLVCPCHICHKCELVNPSPKYRCTK--LIVCIMCPATFHTGDWCIPAGSVELNTGEIICPRHL-VDLNFSMNIMVPPFVARVKSDLQERIYGNTLTKISEPMTITPSTVTKPTNVNWCFKCGEGGELLCCETCPAAYHFKCTDLKEIPQKFYCPDCASFCYRSYGEIVWIKCGTHPWWPGQILHLENVPKNIAAKKHANGQFVVQFFGSRDYMWRDHGNVFLYEKEDECNSKTSKYRYNNIFLEGIKEAAIGYVTREEKWQSGSC-DHVMNSKIYNKIQVNK--CPLELRRKVVPETPHCNCISFDPKSDCSIGSGCFNVASKCECDPQICNLGDKCKNQNFVKRIYPKQYTFWANDRGWGLKADEFIKTKQFVNEYIGEIITMEESEKRILWANENNITDFYFMELDNGRLIDARQFSNLSRFINNSCDPNLVAEKWIVNREHRIGLFALRDIQKGEELTFQYNLQNKSSNRIVCKCFSVNCSGFLGEAPKMAXXXXXXXXXXXXXXXXXXXXXXXCKSFLTDKNSNSQCFRCGEIIDMLSSIVCSVGPCMKTYHSVCLNLNMANYVQSSWICPHHYCDVCARPSHHFSSNTTESYC 2768
C+ C + +++V C FH+ CL K D C +C GI C+AC + +E RC + C K++H C+ P+ T F G L CP H C C + + K++ TK L+ C+ CP +H GD C+ AGS + I+C H +S + V NV+WCF C +GG+LLCCE+CPAA+H C ++ +YC DC + Y +I+W+K GT+ WWP +I H N+P NI +H G+F V FFGSRDY W G VF Y + D SK + +F + EA + + K ++ + Y I+VN+ +++ V E P CNC D + C S C N + EC PQ+C G++C NQ+F KR+YP+ +GWGL A IK +FVNEYIGE+I EE RI +A+ENNIT+FY + +D R+IDA N SRF+N+SC PN +KW VN + R+GLFA+ I G ELTF YNL + + +C+C + NCSGFLG+ PK + + + + K S +CFRCG D ++C C K YH CLNL + W CP H+CDVC + S F S+C
Sbjct: 578 CQVCEQAGEDLVPCEGQCCGMFHLHCL-----GPSFKPEDKLLCQQCRAGIHSCFACKQ-----SEGEVRRCHVVHCGKFYHEACIRLNPL---TVFDNKG-LRCPLHACLSCHYGSRT-KHKSTKGRLMRCLRCPVAYHVGDLCVAAGSEMITNTAIVCTNHFNAKKGYSHHSHV--------------------------------------NVSWCFVCSKGGQLLCCESCPAAFHPDCLNIAMPDGSWYCNDCRAGKKPRYRDIIWVKLGTYRWWPAEIQHPRNIPTNIQHLRHEIGEFPVFFFGSRDYFWTHQGRVFPYMEGDR-GSKHQRTGIGRVFKNALLEAEARFKEMKMKREAKEAQESSRKPPPYKFIKVNRPYGRVQVYTADVSEIPKCNCKPTDERP-CGFESECLNRMLQYECHPQVCPSGERCCNQDFTKRLYPETKIIKTPGKGWGLVALRDIKKGKFVNEYIGELIDEEECRARIKYAHENNITNFYMLTIDKDRIIDAGPKGNYSRFMNHSCQPNCETQKWTVNGDTRVGLFAVCHIPAGTELTFNYNLDCLGNEKTICRCGAPNCSGFLGDRPKNSNGHAAEPKGKRPKRKYKKRRSE------GKKKSEDECFRCG---DGGQLVLCDKKTCTKAYHLSCLNLTKRPF--GRWDCPWHHCDVCGKNSEAFCQLCPNSFC 1210
BLAST of NSD-1 vs. Ensembl Medaka
Match: nsd1b (histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific [Source:NCBI gene;Acc:101161079]) HSP 1 Score: 390.193 bits (1001), Expect = 1.230e-114 Identity = 239/700 (34.14%), Postives = 344/700 (49.14%), Query Frame = 3
Query: 693 CRYCLETKNIVQCNKCLFNNFHVKCLEFLQNSIETKINDLDRCLECSLGIIRCYACYKIVDISNEQGFMRCIIKTCTKWFHTNCLET-GPMLEMTKFPKPGQLVCPCHICHKCELVNP-SPKYRCTKLIVCIMCPATFHTGDWCIPAGSVELNTGEIICPRHLVDLNFSMNIMVPPFVARVKSDLQERIYGNTLTKISEPMTITPSTVTKPTNVNWCFKCGEGGELLCCETCPAAYHFKCTDLKEIPQKFYCPDCASFCYRSYGEIVWIKCGTHPWWPGQILHLENVPKNIAAKKHANGQFVVQFFGSRDYMWRDHGNVFLYEKEDECNSKTSKYRYNNIFLEGIKEAAIGY--VTREEKWQSGSCDHVMNSKI--YNKIQVNK--CPLELRRKVVPETPHCNCISFDPKSDCSIGSGCFNVASKCECDPQICNLGDKCKNQNFVKRIYPKQYTFWANDRGWGLKADEFIKTKQFVNEYIGEIITMEESEKRILWANENNITDFYFMELDNGRLIDARQFSNLSRFINNSCDPNLVAEKWIVNREHRIGLFALRDIQKGEELTFQYNLQNKSSNRIVCKCFSVNCSGFLGEAPKMAXXXXXXXXXXXXXXXXXXXXXXXCKSFLTDKNSNSQCFRCGEIIDMLSSIVCSVGPCMKTYHSVCLNLNMANYVQSSWICPHHYCDVCARPSHHFSSNTTESYC 2768
C+ C +T ++ C FH+ C+ L ++ + K C EC G+ C+ C K + RC+I C K++H C+ P + + C H+C C + NP S +L+ C+ CP +H D C+ AGSV L++ I+CP H F R E + NV+WCF C EGG LLCCE+CPAA+H +C +++ +YC DC + Y +I+W+K G + WWP ++ H + +P+NI +H G+F V FFGS DY+W VF Y D + + + + + ++EAA+ + + E++ + D + K Y I+VN+ +++ + E P CNC + D +S C S C N EC+PQ+C G+KC NQ F KR Y + F RGWGL+ IK QFV+EY+GE+I EE RI A EN+I +FY + LD R+IDA N +RF+N+ C PN +KW VN + R+GLFAL D++ G ELTF YNL+ + + VCKC + NCSGFLG PK S K K+ + K + K +CF CG+ M+S C C K YH+ CLNL W CP H CDVC + + F SYC
Sbjct: 1285 CQVCEKTGELLLCEGQCCGAFHLACIS-LADAPKGKF----VCPECKSGVHTCFVCKK-----RGEDVRRCMIPVCGKFYHGECITNHAPTAPVNR-----GFRCSIHVCLTCFIANPNSSSISKGRLVRCVRCPVAYHATDLCMAAGSVVLSSNSIVCPNH--------------FTPRRGVKNHEHV-----------------------NVSWCFVCTEGGSLLCCESCPAAFHRECLNIEMPKGSWYCNDCKAGKKPHYKDILWVKVGRYRWWPAEVSHPKTIPENIQRMRHDVGEFPVHFFGSNDYLWTYQARVFPYMDVDANSKEKMGKGVDTTYKKALEEAAVRFRELQAEKELRQLQEDRKNDRKPPPYKHIKVNRPIGKVQIFTADLSEVPRCNCKATD-ESPCGSDSECINRMLLYECNPQVCPAGEKCLNQAFTKRQYSQVEIFRTLSRGWGLRCVHDIKKGQFVSEYVGEVIDEEECRSRIRHAQENDICNFYMLTLDKDRIIDAGPKGNEARFMNHCCQPNCETQKWTVNGDTRVGLFALVDVKAGTELTFNYNLECLGNGKTVCKCGAPNCSGFLGVRPKNNPPSDDKGRKMKRRGHGRRK-----KKVVLAKEREDECFSCGDGGQMVS---CKKPGCPKVYHADCLNL--TKRPAGRWECPWHQCDVCGKEAASFCEMCPSSYC 1921
BLAST of NSD-1 vs. Ensembl Medaka
Match: nsd1b (histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific [Source:NCBI gene;Acc:101161079]) HSP 1 Score: 389.808 bits (1000), Expect = 2.482e-114 Identity = 239/700 (34.14%), Postives = 344/700 (49.14%), Query Frame = 3
Query: 693 CRYCLETKNIVQCNKCLFNNFHVKCLEFLQNSIETKINDLDRCLECSLGIIRCYACYKIVDISNEQGFMRCIIKTCTKWFHTNCLET-GPMLEMTKFPKPGQLVCPCHICHKCELVNP-SPKYRCTKLIVCIMCPATFHTGDWCIPAGSVELNTGEIICPRHLVDLNFSMNIMVPPFVARVKSDLQERIYGNTLTKISEPMTITPSTVTKPTNVNWCFKCGEGGELLCCETCPAAYHFKCTDLKEIPQKFYCPDCASFCYRSYGEIVWIKCGTHPWWPGQILHLENVPKNIAAKKHANGQFVVQFFGSRDYMWRDHGNVFLYEKEDECNSKTSKYRYNNIFLEGIKEAAIGY--VTREEKWQSGSCDHVMNSKI--YNKIQVNK--CPLELRRKVVPETPHCNCISFDPKSDCSIGSGCFNVASKCECDPQICNLGDKCKNQNFVKRIYPKQYTFWANDRGWGLKADEFIKTKQFVNEYIGEIITMEESEKRILWANENNITDFYFMELDNGRLIDARQFSNLSRFINNSCDPNLVAEKWIVNREHRIGLFALRDIQKGEELTFQYNLQNKSSNRIVCKCFSVNCSGFLGEAPKMAXXXXXXXXXXXXXXXXXXXXXXXCKSFLTDKNSNSQCFRCGEIIDMLSSIVCSVGPCMKTYHSVCLNLNMANYVQSSWICPHHYCDVCARPSHHFSSNTTESYC 2768
C+ C +T ++ C FH+ C+ L ++ + K C EC G+ C+ C K + RC+I C K++H C+ P + + C H+C C + NP S +L+ C+ CP +H D C+ AGSV L++ I+CP H F R E + NV+WCF C EGG LLCCE+CPAA+H +C +++ +YC DC + Y +I+W+K G + WWP ++ H + +P+NI +H G+F V FFGS DY+W VF Y D + + + + + ++EAA+ + + E++ + D + K Y I+VN+ +++ + E P CNC + D +S C S C N EC+PQ+C G+KC NQ F KR Y + F RGWGL+ IK QFV+EY+GE+I EE RI A EN+I +FY + LD R+IDA N +RF+N+ C PN +KW VN + R+GLFAL D++ G ELTF YNL+ + + VCKC + NCSGFLG PK S K K+ + K + K +CF CG+ M+S C C K YH+ CLNL W CP H CDVC + + F SYC
Sbjct: 1691 CQVCEKTGELLLCEGQCCGAFHLACIS-LADAPKGKF----VCPECKSGVHTCFVCKK-----RGEDVRRCMIPVCGKFYHGECITNHAPTAPVNRG-----FRCSIHVCLTCFIANPNSSSISKGRLVRCVRCPVAYHATDLCMAAGSVVLSSNSIVCPNH--------------FTPRRGVKNHEHV-----------------------NVSWCFVCTEGGSLLCCESCPAAFHRECLNIEMPKGSWYCNDCKAGKKPHYKDILWVKVGRYRWWPAEVSHPKTIPENIQRMRHDVGEFPVHFFGSNDYLWTYQARVFPYMDVDANSKEKMGKGVDTTYKKALEEAAVRFRELQAEKELRQLQEDRKNDRKPPPYKHIKVNRPIGKVQIFTADLSEVPRCNCKATD-ESPCGSDSECINRMLLYECNPQVCPAGEKCLNQAFTKRQYSQVEIFRTLSRGWGLRCVHDIKKGQFVSEYVGEVIDEEECRSRIRHAQENDICNFYMLTLDKDRIIDAGPKGNEARFMNHCCQPNCETQKWTVNGDTRVGLFALVDVKAGTELTFNYNLECLGNGKTVCKCGAPNCSGFLGVRPKNNPPSDDKGRKMKRRGHGRRK-----KKVVLAKEREDECFSCGDGGQMVS---CKKPGCPKVYHADCLNL--TKRPAGRWECPWHQCDVCGKEAASFCEMCPSSYC 2327
BLAST of NSD-1 vs. Ensembl Medaka
Match: nsd1b (histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific [Source:NCBI gene;Acc:101161079]) HSP 1 Score: 389.808 bits (1000), Expect = 2.482e-114 Identity = 239/700 (34.14%), Postives = 344/700 (49.14%), Query Frame = 3
Query: 693 CRYCLETKNIVQCNKCLFNNFHVKCLEFLQNSIETKINDLDRCLECSLGIIRCYACYKIVDISNEQGFMRCIIKTCTKWFHTNCLET-GPMLEMTKFPKPGQLVCPCHICHKCELVNP-SPKYRCTKLIVCIMCPATFHTGDWCIPAGSVELNTGEIICPRHLVDLNFSMNIMVPPFVARVKSDLQERIYGNTLTKISEPMTITPSTVTKPTNVNWCFKCGEGGELLCCETCPAAYHFKCTDLKEIPQKFYCPDCASFCYRSYGEIVWIKCGTHPWWPGQILHLENVPKNIAAKKHANGQFVVQFFGSRDYMWRDHGNVFLYEKEDECNSKTSKYRYNNIFLEGIKEAAIGY--VTREEKWQSGSCDHVMNSKI--YNKIQVNK--CPLELRRKVVPETPHCNCISFDPKSDCSIGSGCFNVASKCECDPQICNLGDKCKNQNFVKRIYPKQYTFWANDRGWGLKADEFIKTKQFVNEYIGEIITMEESEKRILWANENNITDFYFMELDNGRLIDARQFSNLSRFINNSCDPNLVAEKWIVNREHRIGLFALRDIQKGEELTFQYNLQNKSSNRIVCKCFSVNCSGFLGEAPKMAXXXXXXXXXXXXXXXXXXXXXXXCKSFLTDKNSNSQCFRCGEIIDMLSSIVCSVGPCMKTYHSVCLNLNMANYVQSSWICPHHYCDVCARPSHHFSSNTTESYC 2768
C+ C +T ++ C FH+ C+ L ++ + K C EC G+ C+ C K + RC+I C K++H C+ P + + C H+C C + NP S +L+ C+ CP +H D C+ AGSV L++ I+CP H F R E + NV+WCF C EGG LLCCE+CPAA+H +C +++ +YC DC + Y +I+W+K G + WWP ++ H + +P+NI +H G+F V FFGS DY+W VF Y D + + + + + ++EAA+ + + E++ + D + K Y I+VN+ +++ + E P CNC + D +S C S C N EC+PQ+C G+KC NQ F KR Y + F RGWGL+ IK QFV+EY+GE+I EE RI A EN+I +FY + LD R+IDA N +RF+N+ C PN +KW VN + R+GLFAL D++ G ELTF YNL+ + + VCKC + NCSGFLG PK S K K+ + K + K +CF CG+ M+S C C K YH+ CLNL W CP H CDVC + + F SYC
Sbjct: 1691 CQVCEKTGELLLCEGQCCGAFHLACIS-LADAPKGKF----VCPECKSGVHTCFVCKK-----RGEDVRRCMIPVCGKFYHGECITNHAPTAPVNRG-----FRCSIHVCLTCFIANPNSSSISKGRLVRCVRCPVAYHATDLCMAAGSVVLSSNSIVCPNH--------------FTPRRGVKNHEHV-----------------------NVSWCFVCTEGGSLLCCESCPAAFHRECLNIEMPKGSWYCNDCKAGKKPHYKDILWVKVGRYRWWPAEVSHPKTIPENIQRMRHDVGEFPVHFFGSNDYLWTYQARVFPYMDVDANSKEKMGKGVDTTYKKALEEAAVRFRELQAEKELRQLQEDRKNDRKPPPYKHIKVNRPIGKVQIFTADLSEVPRCNCKATD-ESPCGSDSECINRMLLYECNPQVCPAGEKCLNQAFTKRQYSQVEIFRTLSRGWGLRCVHDIKKGQFVSEYVGEVIDEEECRSRIRHAQENDICNFYMLTLDKDRIIDAGPKGNEARFMNHCCQPNCETQKWTVNGDTRVGLFALVDVKAGTELTFNYNLECLGNGKTVCKCGAPNCSGFLGVRPKNNPPSDDKGRKMKRRGHGRRK-----KKVVLAKEREDECFSCGDGGQMVS---CKKPGCPKVYHADCLNL--TKRPAGRWECPWHQCDVCGKEAASFCEMCPSSYC 2327
BLAST of NSD-1 vs. Ensembl Medaka
Match: nsd1b (histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific [Source:NCBI gene;Acc:101161079]) HSP 1 Score: 389.423 bits (999), Expect = 3.283e-114 Identity = 239/700 (34.14%), Postives = 344/700 (49.14%), Query Frame = 3
Query: 693 CRYCLETKNIVQCNKCLFNNFHVKCLEFLQNSIETKINDLDRCLECSLGIIRCYACYKIVDISNEQGFMRCIIKTCTKWFHTNCLET-GPMLEMTKFPKPGQLVCPCHICHKCELVNP-SPKYRCTKLIVCIMCPATFHTGDWCIPAGSVELNTGEIICPRHLVDLNFSMNIMVPPFVARVKSDLQERIYGNTLTKISEPMTITPSTVTKPTNVNWCFKCGEGGELLCCETCPAAYHFKCTDLKEIPQKFYCPDCASFCYRSYGEIVWIKCGTHPWWPGQILHLENVPKNIAAKKHANGQFVVQFFGSRDYMWRDHGNVFLYEKEDECNSKTSKYRYNNIFLEGIKEAAIGY--VTREEKWQSGSCDHVMNSKI--YNKIQVNK--CPLELRRKVVPETPHCNCISFDPKSDCSIGSGCFNVASKCECDPQICNLGDKCKNQNFVKRIYPKQYTFWANDRGWGLKADEFIKTKQFVNEYIGEIITMEESEKRILWANENNITDFYFMELDNGRLIDARQFSNLSRFINNSCDPNLVAEKWIVNREHRIGLFALRDIQKGEELTFQYNLQNKSSNRIVCKCFSVNCSGFLGEAPKMAXXXXXXXXXXXXXXXXXXXXXXXCKSFLTDKNSNSQCFRCGEIIDMLSSIVCSVGPCMKTYHSVCLNLNMANYVQSSWICPHHYCDVCARPSHHFSSNTTESYC 2768
C+ C +T ++ C FH+ C+ L ++ + K C EC G+ C+ C K + RC+I C K++H C+ P + + C H+C C + NP S +L+ C+ CP +H D C+ AGSV L++ I+CP H F R E + NV+WCF C EGG LLCCE+CPAA+H +C +++ +YC DC + Y +I+W+K G + WWP ++ H + +P+NI +H G+F V FFGS DY+W VF Y D + + + + + ++EAA+ + + E++ + D + K Y I+VN+ +++ + E P CNC + D +S C S C N EC+PQ+C G+KC NQ F KR Y + F RGWGL+ IK QFV+EY+GE+I EE RI A EN+I +FY + LD R+IDA N +RF+N+ C PN +KW VN + R+GLFAL D++ G ELTF YNL+ + + VCKC + NCSGFLG PK S K K+ + K + K +CF CG+ M+S C C K YH+ CLNL W CP H CDVC + + F SYC
Sbjct: 1608 CQVCEKTGELLLCEGQCCGAFHLACIS-LADAPKGKF----VCPECKSGVHTCFVCKK-----RGEDVRRCMIPVCGKFYHGECITNHAPTAPVNRG-----FRCSIHVCLTCFIANPNSSSISKGRLVRCVRCPVAYHATDLCMAAGSVVLSSNSIVCPNH--------------FTPRRGVKNHEHV-----------------------NVSWCFVCTEGGSLLCCESCPAAFHRECLNIEMPKGSWYCNDCKAGKKPHYKDILWVKVGRYRWWPAEVSHPKTIPENIQRMRHDVGEFPVHFFGSNDYLWTYQARVFPYMDVDANSKEKMGKGVDTTYKKALEEAAVRFRELQAEKELRQLQEDRKNDRKPPPYKHIKVNRPIGKVQIFTADLSEVPRCNCKATD-ESPCGSDSECINRMLLYECNPQVCPAGEKCLNQAFTKRQYSQVEIFRTLSRGWGLRCVHDIKKGQFVSEYVGEVIDEEECRSRIRHAQENDICNFYMLTLDKDRIIDAGPKGNEARFMNHCCQPNCETQKWTVNGDTRVGLFALVDVKAGTELTFNYNLECLGNGKTVCKCGAPNCSGFLGVRPKNNPPSDDKGRKMKRRGHGRRK-----KKVVLAKEREDECFSCGDGGQMVS---CKKPGCPKVYHADCLNL--TKRPAGRWECPWHQCDVCGKEAASFCEMCPSSYC 2244
BLAST of NSD-1 vs. Planmine SMEST
Match: SMESG000015015.1 (SMESG000015015.1) HSP 1 Score: 1719.13 bits (4451), Expect = 0.000e+0 Identity = 898/900 (99.78%), Postives = 899/900 (99.89%), Query Frame = 3
Query: 99 MFKEXXXXXXXXXXXXXXXXXXXRTEDSRSKSYKVGQIICGKVGKYPWWPCMVNTIPTSNEPRVLVSYFGKKNDYSYLFDDCTMYAQTKSDFENIFKLHNHDKKTLARLAHYKKQLDLAWKEVEIASLLDENSRFELYKIKCEIKESINXXXXXXXXXXXXXXXXXXXXQEIIKREPIKYAFDELTLPFVSVKLTNKNCRYCLETKNIVQCNKCLFNNFHVKCLEFLQNSIETKINDLDRCLECSLGIIRCYACYKIVDISNEQGFMRCIIKTCTKWFHTNCLETGPMLEMTKFPKPGQLVCPCHICHKCELVNPSPKYRCTKLIVCIMCPATFHTGDWCIPAGSVELNTGEIICPRHLVDLNFSMNIMVPPFVARVKSDLQERIYGNTLTKISEPMTITPSTVTKPTNVNWCFKCGEGGELLCCETCPAAYHFKCTDLKEIPQKFYCPDCASFCYRSYGEIVWIKCGTHPWWPGQILHLENVPKNIAAKKHANGQFVVQFFGSRDYMWRDHGNVFLYEKEDECNSKTSKYRYNNIFLEGIKEAAIGYVTREEKWQSGSCDHVMNSKIYNKIQVNKCPLELRRKVVPETPHCNCISFDPKSDCSIGSGCFNVASKCECDPQICNLGDKCKNQNFVKRIYPKQYTFWANDRGWGLKADEFIKTKQFVNEYIGEIITMEESEKRILWANENNITDFYFMELDNGRLIDARQFSNLSRFINNSCDPNLVAEKWIVNREHRIGLFALRDIQKGEELTFQYNLQNKSSNRIVCKCFSVNCSGFLGEAPKMAXXXXXXXXXXXXXXXXXXXXXXXCKSFLTDKNSNSQCFRCGEIIDMLSSIVCSVGPCMKTYHSVCLNLNMANYVQSSWICPHHYCDVCARPSHHFSSNTTESYCNKDFIKKFNS 2798
MFKELTNLNNNSSNVSLLSTSSNRTEDSRSKSYKVGQIICGKVGKYPWWPCMVNTIPTSNEPRVLVSYFGKKNDYSYLFDDCTMYAQTKSDFENIFKLHNHDKKTLARLAHYKKQLDLAWKEVEIASLLDENSRFELYKIKCEIKESINPPKKRIRPPKPKKEKAASKPQEIIKREPIKYAFDELTLPFVSVKLTNKNCRYCLETKNIVQCNKCLFNNFHVKCLEFLQNSIETKINDLDRCLECSLGIIRCYACYKIVDISNEQGFMRCIIKTCTKWFHTNCLETGPMLEMTKFPKPGQLVCPCHICHKCELVNPSPKYRCTKLIVCIMCPATFHTGDWCIPAGSVELNTGEIICPRHLVDLNFSMNIMVPPFVARVKSDLQERIYGNTLTKISEPMTITPSTVTKPTNVNWCFKCGEGGELLCCETCPAAYHFKCTDLKEIPQKFYCPDCASFCYRSYGEIVWIKCGTHPWWPGQILHLENVPKNIAAKKHANGQFVVQFFGSRDYMWRDHGNVFLYEKEDECNSKTSKYRYNNIFLE IKEAAIGYVTREEKWQSGSCDHVMNSKIYNKIQVNKCPLELRRKVVPETPHCNCISFDPKSDCSIGSGCFNVASKCECDPQICNLGDKCKNQNFVKRIYPKQYTFWANDRGWGLKADEFIKTKQFVNEYIGEIITMEESEKRILWANENNI+DFYFMELDNGRLIDARQFSNLSRFINNSCDPNLVAEKWIVNREHRIGLFALRDIQKGEELTFQYNLQNKSSNRIVCKCFSVNCSGFLGEAPKMAKVSKLKSDTSKKSKGDTTESESSCKSFLTDKNSNSQCFRCGEIIDMLSSIVCSVGPCMKTYHSVCLNLNMANYVQSSWICPHHYCDVCARPSHHFSSNTTESYCNKDFIKKFNS
Sbjct: 1 MFKELTNLNNNSSNVSLLSTSSNRTEDSRSKSYKVGQIICGKVGKYPWWPCMVNTIPTSNEPRVLVSYFGKKNDYSYLFDDCTMYAQTKSDFENIFKLHNHDKKTLARLAHYKKQLDLAWKEVEIASLLDENSRFELYKIKCEIKESINPPKKRIRPPKPKKEKAASKPQEIIKREPIKYAFDELTLPFVSVKLTNKNCRYCLETKNIVQCNKCLFNNFHVKCLEFLQNSIETKINDLDRCLECSLGIIRCYACYKIVDISNEQGFMRCIIKTCTKWFHTNCLETGPMLEMTKFPKPGQLVCPCHICHKCELVNPSPKYRCTKLIVCIMCPATFHTGDWCIPAGSVELNTGEIICPRHLVDLNFSMNIMVPPFVARVKSDLQERIYGNTLTKISEPMTITPSTVTKPTNVNWCFKCGEGGELLCCETCPAAYHFKCTDLKEIPQKFYCPDCASFCYRSYGEIVWIKCGTHPWWPGQILHLENVPKNIAAKKHANGQFVVQFFGSRDYMWRDHGNVFLYEKEDECNSKTSKYRYNNIFLERIKEAAIGYVTREEKWQSGSCDHVMNSKIYNKIQVNKCPLELRRKVVPETPHCNCISFDPKSDCSIGSGCFNVASKCECDPQICNLGDKCKNQNFVKRIYPKQYTFWANDRGWGLKADEFIKTKQFVNEYIGEIITMEESEKRILWANENNISDFYFMELDNGRLIDARQFSNLSRFINNSCDPNLVAEKWIVNREHRIGLFALRDIQKGEELTFQYNLQNKSSNRIVCKCFSVNCSGFLGEAPKMAKVSKLKSDTSKKSKGDTTESESSCKSFLTDKNSNSQCFRCGEIIDMLSSIVCSVGPCMKTYHSVCLNLNMANYVQSSWICPHHYCDVCARPSHHFSSNTTESYCNKDFIKKFNS 900
BLAST of NSD-1 vs. Planmine SMEST
Match: SMESG000039925.1 (SMESG000039925.1) HSP 1 Score: 515.383 bits (1326), Expect = 1.450e-165 Identity = 320/959 (33.37%), Postives = 482/959 (50.26%), Query Frame = 3
Query: 171 TEDSRSKSYKVGQIICGKVGKYPWWPCMVNTIPTSN-------EPRVLVSYFGKKNDYSYLFDDCTMYAQTKSDFENIFKL---HNHDKKTLARLAHYKKQLDL---AWKEVEIASLLDENSRFELYKIKCEIKESINXXXXXXXXXXXXXXXXXXXXQEIIKREPIK--YAFDELTLPFVSVKLTNKNCRYCLETKN------IVQCNKCLFNNFHVKCLEFLQNSIE-----TKINDLDRCLECSLGIIRCYACYKIVDISNEQGFMRCIIKTCTKWFHTNCLETGPMLEMTKFPKPGQLVCPCHICHKCELVNPSPKYRCTKLIVCIMCPATFHTGDWCIPAGSVELNTGEIICPRHLVDLNFSMNIMVPPFVARVKSDLQERIYGNT----LTKISEPMTITPSTVTKPT--------NVNWCFKCGEGGELLCCETCPAAYHFKCTDLKEIPQKFYCPDCASFCYRSYGEIVWIKCGTHPWWPGQILHLENVPKNIAAKKHANGQFVVQFFGSRDYMWRDHGNVFLYEKEDECNSKTSKYRYNNIFLE-------------------GIKEAAIGYVTREEKWQSGSCDHVMNSK----IYNKIQVNKCPLELRRKVVP----ETPHCNCISFDPKSD-CSIGSGCFNVASKCECDPQICNLGDKCKNQNFVKRIYPKQYTFWANDRGWGLKADEFIKTKQFVNEYIGEIITMEESEKRILWANENNITDFYFMELDNGRLIDARQFSNLSRFINNSCDPNLVAEKWIVNREHRIGLFALRDIQKGEELTFQYNLQNKSSNRIVCKCFSVNCSGFLGEAPKMAXXXXXXXXXXXXXXXXXX------------------XXXXXCKSFLTDKNSNSQCFRCGEIIDMLSSIVCSVGPCMKTYHSVCLNLNMANYVQSSWICPHHYCDVCARPSHHFSSNTTESYCNKDFIKKFN 2795
T+++ S+ Y VG+++ KV +PWWPCM+ P N + + V+YFG ++ + M + K F++ K +N K + + + ++ + +WKE E A ++ R ++Y I + + + + + + +++ K++ + + F L LP S N C CLE + + C FH CL L + + TK+ + +C++C+ + RC+ C K+ + M+C C +++H+NCL G ++ + + G L CP HICH C + +P +C+ + C+MCP++FH GDWCIPAGS E+N IICP+HL + S I V PF+ +K+ R+ N+ LT ++P + KP NV WCF C +GG+L+CCE CPA+ H C + EIP F C DC S Y YG+I W+K G++ WWPGQI+H N P+ + H +GQF+VQFFG+ DY W + + F +E D+ + K N+ E +K AA V R KW+S ++N K Y I+ N P+ R P E P C C D +D C S C N EC P +C G+ C+NQ F++R YPKQ F ++RGW L+ E IK FVNEY+GE+I E+ +R+ A+E N+++FY MELD R+IDA +N+SRF+N+SC PN+ +KW VN + RIGLFAL I+ GEELTF YN + ++ CKC + NCSGFLG+ PK A SD + + + ++F K + +C+RCG+ I CS C + YH C++L +N +S W+CP H CD C R S +F S T SYC + +FN
Sbjct: 126 TQENTSEEYYVGRLLWAKVKSHPWWPCMIYYSPEKNFYKEMFHKKVIHVAYFGPYVQRGWVSINSVMSFEGKLKFDDHVKELTENNSPKNIIQKYTIPQSRMKIFSESWKEAEEAMMMPVKDRIDVYGISYKNLNGESSSENEEKISEEEFDESDMDSSPCKKQKIVAETFEFQNLKLPTFSNCKKNPLCFLCLEENDESGNNLVANCTGGCGQQFHPDCLRLLFDYLTSKEPTTKVINYLKCVDCNRNVRRCFICQKLGKNDKKDEMMKCSTSNCGRYYHSNCLYNGHYQQLITYNRSGSLTCPSHICHACYIDDPEAVKQCSNHVRCLMCPSSFHKGDWCIPAGSKEINDNYIICPKHL-SMGGSAEITVTPFMDCIKNG---RVKLNSVNFKLTPFNDPQNKDFWVLEKPLKVSKSKSHNVTWCFLCPDGGKLICCERCPASLHQHCAAIDEIPVVFICDDCQSGRYPRYGDIYWLKIGSYRWWPGQIIHPNNAPEKVLKASHGDGQFLVQFFGTNDYYWMNKTHAFPFEDGDDKTGEMKKIIANSSLDEVTRDTSGNGNTKLDRDYRKSLKIAAKALVLRTSKWES-----ILNLKNKPSQYRSIKTN-VPIGNVRINKPADLTEIPQCECRPSDKCNDPCGPTSECMNRELMYECHPLVCRNGENCRNQRFMRREYPKQEVFSTDNRGWALRTLEPIKKGAFVNEYVGELIDEAEANRRLKKAHETNVSNFYMMELDGQRIIDAGPAANISRFMNHSCSPNVYTQKWSVNGDTRIGLFALHTIKAGEELTFNYNFFSLGQKKLPCKCGASNCSGFLGDPPKTASPDSEPSDKDSILELKKSYNSNNKIDKKKILINKKPNNTVDLQNFFQKKLVDQECYRCGQ---NNCEIFCSHQHCPRVYHLQCVSL--SNIPKSLWLCPWHCCDDCGRISEYFCSECTTSYC---LLHRFN 1066
BLAST of NSD-1 vs. Planmine SMEST
Match: SMESG000039925.1 (SMESG000039925.1) HSP 1 Score: 511.916 bits (1317), Expect = 4.555e-164 Identity = 322/974 (33.06%), Postives = 479/974 (49.18%), Query Frame = 3
Query: 171 TEDSRSKSYKVGQIICGKVGKYPWWPCMVNTIPTSN-------EPRVLVSYFGKKNDYSYLFDDCTMYAQTKSDFENIFKL---HNHDKKTLARLAHYKKQLDL---AWKEVEIASLLDENSRFELYKIKCE-----IKESINXXXXXXXXXXXXXXXXXXXXQEIIKREPI------------KYAFDELTLPFVSVKLTNKNCRYCLETKN------IVQCNKCLFNNFHVKCLEFLQNSIE-----TKINDLDRCLECSLGIIRCYACYKIVDISNEQGFMRCIIKTCTKWFHTNCLETGPMLEMTKFPKPGQLVCPCHICHKCELVNPSPKYRCTKLIVCIMCPATFHTGDWCIPAGSVELNTGEIICPRHLVDLNFSMNIMVPPFVARVKSDLQERIYGNT----LTKISEPMTITPSTVTKPT--------NVNWCFKCGEGGELLCCETCPAAYHFKCTDLKEIPQKFYCPDCASFCYRSYGEIVWIKCGTHPWWPGQILHLENVPKNIAAKKHANGQFVVQFFGSRDYMWRDHGNVFLYEKEDECNSKTSKYRYNNIFLE-------------------GIKEAAIGYVTREEKWQSGSCDHVMNSK----IYNKIQVNKCPLELRRKVVP----ETPHCNCISFDPKSD-CSIGSGCFNVASKCECDPQICNLGDKCKNQNFVKRIYPKQYTFWANDRGWGLKADEFIKTKQFVNEYIGEIITMEESEKRILWANENNITDFYFMELDNGRLIDARQFSNLSRFINNSCDPNLVAEKWIVNREHRIGLFALRDIQKGEELTFQYNLQNKSSNRIVCKCFSVNCSGFLGEAPKMAXXXXXXXXXXXXXXXXXX------------------XXXXXCKSFLTDKNSNSQCFRCGEIIDMLSSIVCSVGPCMKTYHSVCLNLNMANYVQSSWICPHHYCDVCARPSHHFSSNTTESYCNKDFIKKFN 2795
T+++ S+ Y VG+++ KV +PWWPCM+ P N + + V+YFG ++ + M + K F++ K +N K + + + ++ + +WKE E A ++ R ++Y I + + + + K Q+I+ + + F L LP S N C CLE + + C FH CL L + + TK+ + +C++C+ + RC+ C K+ + M+C C +++H+NCL G ++ + + G L CP HICH C + +P +C+ + C+MCP++FH GDWCIPAGS E+N IICP+HL + S I V PF+ +K+ R+ N+ LT ++P + KP NV WCF C +GG+L+CCE CPA+ H C + EIP F C DC S Y YG+I W+K G++ WWPGQI+H N P+ + H +GQF+VQFFG+ DY W + + F +E D+ + K N+ E +K AA V R KW+S ++N K Y I+ N P+ R P E P C C D +D C S C N EC P +C G+ C+NQ F++R YPKQ F ++RGW L+ E IK FVNEY+GE+I E+ +R+ A+E N+++FY MELD R+IDA +N+SRF+N+SC PN+ +KW VN + RIGLFAL I+ GEELTF YN + ++ CKC + NCSGFLG+ PK A SD + + + ++F K + +C+RCG+ I CS C + YH C++L +N +S W+CP H CD C R S +F S T SYC + +FN
Sbjct: 126 TQENTSEEYYVGRLLWAKVKSHPWWPCMIYYSPEKNFYKEMFHKKVIHVAYFGPYVQRGWVSINSVMSFEGKLKFDDHVKELTENNSPKNIIQKYTIPQSRMKIFSESWKEAEEAMMMPVKDRIDVYGISYKNLNGESSSENEEKISEEEFDESDMDSSPCKKQKIVAETALTIVYIGRFSIVLNFEFQNLKLPTFSNCKKNPLCFLCLEENDESGNNLVANCTGGCGQQFHPDCLRLLFDYLTSKEPTTKVINYLKCVDCNRNVRRCFICQKLGKNDKKDEMMKCSTSNCGRYYHSNCLYNGHYQQLITYNRSGSLTCPSHICHACYIDDPEAVKQCSNHVRCLMCPSSFHKGDWCIPAGSKEINDNYIICPKHL-SMGGSAEITVTPFMDCIKNG---RVKLNSVNFKLTPFNDPQNKDFWVLEKPLKVSKSKSHNVTWCFLCPDGGKLICCERCPASLHQHCAAIDEIPVVFICDDCQSGRYPRYGDIYWLKIGSYRWWPGQIIHPNNAPEKVLKASHGDGQFLVQFFGTNDYYWMNKTHAFPFEDGDDKTGEMKKIIANSSLDEVTRDTSGNGNTKLDRDYRKSLKIAAKALVLRTSKWES-----ILNLKNKPSQYRSIKTN-VPIGNVRINKPADLTEIPQCECRPSDKCNDPCGPTSECMNRELMYECHPLVCRNGENCRNQRFMRREYPKQEVFSTDNRGWALRTLEPIKKGAFVNEYVGELIDEAEANRRLKKAHETNVSNFYMMELDGQRIIDAGPAANISRFMNHSCSPNVYTQKWSVNGDTRIGLFALHTIKAGEELTFNYNFFSLGQKKLPCKCGASNCSGFLGDPPKTASPDSEPSDKDSILELKKSYNSNNKIDKKKILINKKPNNTVDLQNFFQKKLVDQECYRCGQ---NNCEIFCSHQHCPRVYHLQCVSL--SNIPKSLWLCPWHCCDDCGRISEYFCSECTTSYC---LLHRFN 1081
BLAST of NSD-1 vs. Planmine SMEST
Match: SMESG000081033.1 (SMESG000081033.1) HSP 1 Score: 261.536 bits (667), Expect = 1.807e-73 Identity = 182/610 (29.84%), Postives = 274/610 (44.92%), Query Frame = 3
Query: 693 CRYCLETKNIVQCNKCLFNNFHVKCLEFLQNSIETKINDLDRCLECSLGIIRCYACYKIVDISNEQGFMRCIIKTCTKWFHTNCLETGPMLEMTKFPKPGQLVCPCHICHKCELVNPS-PKYRCTKLIVCIMCPATFHTGDWCIPAGSVELNTGEIICPRHLVDLNFSMNIMVPPFVARVKSDLQERIYGNTLTKISEPMTITPSTVTKPTNVNWCFKCGEGGELLCCETCPAAYHFKCTDLKEIPQKFYCPDCASFCYRSYGEIVWIKCGTHPWWPGQILHLENVPKNIAAKKHANGQFVVQFFGSRDYMWRDHGNVFLYE--------KEDECNSKTSKYRYNNIFLEG-IKEAAIGYVTREEKWQSGSCDHVMNSKIYNKIQVNKC-----------------PLELRRKVVPETPHCNCISFDPKSDCSIGSGCFNVASKCECDPQICNLGDKCKNQNFVKRIYPKQYTFWANDRGWGLKADEFIKTKQFVNEYIGEIITMEESEKRILWANENNITDFYFMELDNGRLIDARQFSNLSRFINNSCDPNLVAEKWIVNREHRIGLFALRDIQKGEELTFQYNLQNK-SSNRIVCKCFSVNCSGFLG 2438
C E ++QC FH+ CL+ L+ + T + +CL+C GI C C K+ I + + C C + +H +CLE + + + L CP H C C + + + C KL+ C+ CP +FH D C+ AG+ EL+ +ICP+H + N L K++ KP + WCFKC + G L C CPA+YH +C ++ C +C +F YGE++++K + WWP +I+H N P NI +G + V F GS +Y W + KE ++ + + + + G I + + + +S S + ++Y + V + P +L KV + C+C+ PK DC N +K EC C KCKNQ F + F ++RG+GLK I F+ EY+GE+IT ESE R+L A + N DFY + L +IDA NLSR++N+SCDPN E WIVN + G+FAL++I +ELTF Y + C C S NC+GFLG
Sbjct: 149 CEIYTENNAVLQCTGICKRYFHLHCLKNLKENQPTSKPNF-QCLDCFSGIYHCILCQKVDKIDD---LLACENSDCGRLYHKSCLEMSNFIGI-EIHDNKILSCPSHYCISCVREDATFAQNPCKKLVECLRCPLSFHCNDLCMAAGAYELSLSHVICPQH---------------------------FENKLVKLN---------AHKPFHPAWCFKCFKTGVKLHCNYCPASYHIECVSDYSEESRYVCYNCRNFRQPRYGEVLFVKVHQYRWWPCEIIHPRNAPMNILKLNRPDGTYPVLFLGSNEYQWVAKTRSIDFNTAQFSSIFKESGGTTRMDRDFSSGLRVAGKIHQVYVNILLMHVPLRSISASSMTAEELYPYVNVKEINQKTVKFKLIKANIIVPPAKLPPKV--QASICDCVDNCPKQDCK------NYLNKIECQITQC---PKCKNQQFTNVDHKNIAVFKTSNRGFGLKTTIPINKNDFIIEYLGELITKNESELRMLNAKKFNAKDFYMIHLTGDLVIDAGPKGNLSRYMNHSCDPNCYLENWIVNGYPKKGVFALKEIGSDQELTFDYRISGVIMKEDAFCLCSSNNCTGFLG 706 HSP 2 Score: 50.0618 bits (118), Expect = 9.328e-6 Identity = 30/86 (34.88%), Postives = 42/86 (48.84%), Query Frame = 3
Query: 2535 FLTDKNSNSQ-------CFRCGEIIDMLSSIVCSVGPCMKTYHSVCLNLNMANYVQSSWICPHHYCDVCARPSHHFSSNTTESYCN 2771
F+ DK+S C+RC D + ++C C KTYH CL L A +W CP H+CD+C +PS F S+C+
Sbjct: 785 FIKDKDSVESKTIHENFCYRC---FDGGNLVLCDKMNCPKTYHLSCLGLEEA--PSGTWYCPWHFCDICGQPSKLFCVRCPASFCD 865
BLAST of NSD-1 vs. Planmine SMEST
Match: SMESG000015096.1 (SMESG000015096.1) HSP 1 Score: 177.563 bits (449), Expect = 2.028e-51 Identity = 81/81 (100.00%), Postives = 81/81 (100.00%), Query Frame = 3
Query: 897 MRCIIKTCTKWFHTNCLETGPMLEMTKFPKPGQLVCPCHICHKCELVNPSPKYRCTKLIVCIMCPATFHTGDWCIPAGSVE 1139
MRCIIKTCTKWFHTNCLETGPMLEMTKFPKPGQLVCPCHICHKCELVNPSPKYRCTKLIVCIMCPATFHTGDWCIPAGSVE
Sbjct: 1 MRCIIKTCTKWFHTNCLETGPMLEMTKFPKPGQLVCPCHICHKCELVNPSPKYRCTKLIVCIMCPATFHTGDWCIPAGSVE 81 The following BLAST results are available for this feature:
BLAST of NSD-1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of NSD-1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of NSD-1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of NSD-1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of NSD-1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of NSD-1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of NSD-1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of NSD-1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of NSD-1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of NSD-1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of NSD-1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 2
BLAST of NSD-1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of NSD-1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of NSD-1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Cross References
External references for this transcript
Sequences
The following sequences are available for this feature:
transcript sequence >SMED30009651 ID=SMED30009651|Name=NSD-1|organism=Schmidtea mediterranea sexual|type=transcript|length=2967bpback to top protein sequence of SMED30009651-orf-1 >SMED30009651-orf-1 ID=SMED30009651-orf-1|Name=SMED30009651-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=915bp MLFNSIIINSISYNMFKELTNLNNNSSNVSLLSTSSNRTEDSRSKSYKVGback to top Aliases
The feature 'NSD-1' has the following synonyms
Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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