Dihydropyrimidinase

Overview
NameDihydropyrimidinase
Smed IDSMED30009564
Length (bp)2022
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Dihydropyrimidinase (SMED30009564) t-SNE clustered cells

Violin plots show distribution of expression levels for Dihydropyrimidinase (SMED30009564) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Dihydropyrimidinase (SMED30009564) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Dihydropyrimidinase (SMED30009564) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020




SMED30009564

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 8

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
central nervous systemSMED30009564SMESG000002633.1 SmedASXL_006380SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015
whole organism asexual adult colorimetric in situ hybridization evidence
X2 cellSMED30009564SMESG000002633.1 SmedASXL_006380SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015
FACS sorted cell population asexual adult RNA-sequencing evidence
nervous systemSMED30009564SMESG000002633.1 dd_Smed_v4_1478_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
muscle cellSMED30009564SMESG000002633.1 dd_Smed_v4_1478_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30009564SMESG000002633.1 dd_Smed_v4_1478_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cilated neuronSMED30009564SMESG000002633.1 dd_Smed_v4_1478_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30009564SMESG000002633.1 Contig42547uc_Smed_v2PMID:29674431
Fincher et al., 2018
FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30009564SMESG000002633.1 Contig42547newmark_estsPMID:29674431
Fincher et al., 2018
FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
BLAST of Dihydropyrimidinase vs. Ensembl Human
Match: DPYSL2 (dihydropyrimidinase like 2 [Source:HGNC Symbol;Acc:HGNC:3014])

HSP 1 Score: 637.491 bits (1643), Expect = 0.000e+0
Identity = 306/585 (52.31%), Postives = 411/585 (70.26%), Query Frame = 1
Query:  112 GVKKVPLHLQSSQNRLCIKGAKIVNDDRMFDADVYIEDGIIKQLGTNLVIPGGVRCVEANGKLLIPGGIDTHTHMEFPFMGTVSSDDFYSGTRAALAGGTTMIIDFVIGQKGTSLIDSYNQYREKADSKVCCDYGLHVIVSSYNESVGNEMEKLASEHGINSFKIFMAYKDSLMLEDDEMYEVFKKCKSIGALAQVHAENGKLIEKKSLELISKGITGPEGHLYSRPEEVECEATNRAIMLADQANCPLYVVHVMSKGAADIISDARRQGKVVFGEPIAAGLGTDGSHYSHSCWRHAAGYVMSPPLRNDRNTSKHLMQLLASGDLECTGTDHCVFKASQKALGKDDFRSIPNGVNGVEDRMSVIWEKGVVTGILDPCKFVAVTSTNAAKIFNIYPKKGRIDIGSDADLVLWNPDVRRTISASTHYQNVDFNIFEGMHCHGVAEMVISGGKVVLEDGNLRVAQGTGKFVPTNPFCNYVFNKVKLRDQCHKTLANKVERQPYDGPVEDLSKEMTNLNMNFDDDTDSQQNAISSEFVNTKRPLTSGGGRHMQDSSFALSGAQIDDNLPTRSGIRTRQPPGGTA--TSL 1860
            G K +P   + + +RL IKG KIVNDD+ F AD+Y+EDG+IKQ+G NL++PGGV+ +EA+ +++IPGGID HT  + P  G  S+DDF+ GT+AALAGGTTMIID V+ + GTSL+ +++Q+RE ADSK CCDY LHV +S +++ +  EME L  +HG+NSF ++MA+KD   L D ++YEV    + IGA+AQVHAENG +I ++   ++  GITGPEGH+ SRPEEVE EA NRAI +A+Q NCPLY+  VMSK +A++I+ AR++G VV+GEPI A LGTDGSHY    W  AA +V SPPL  D  T   L  LL+ GDL+ TG+ HC F  +QKA+GKD+F  IP G NG E+RMSVIW+K VVTG +D  +FVAVTSTNAAK+FN+YP+KGRI +GSDADLV+W+PD  +TISA TH  ++++NIFEGM C G   +VIS GK+VLEDG L V +G+G+++P  PF ++V+ ++K R +  +     V R  YDGPV ++S     +            +A +S       P+     R++  S F+LSGAQIDDN+P R+  R   PPGG A  TSL
Sbjct:    5 GKKNIP---RITSDRLLIKGGKIVNDDQSFYADIYMEDGLIKQIGENLIVPGGVKTIEAHSRMVIPGGIDVHTRFQMPDQGMTSADDFFQGTKAALAGGTTMIIDHVVPEPGTSLLAAFDQWREWADSKSCCDYSLHVDISEWHKGIQEEMEALVKDHGVNSFLVYMAFKDRFQLTDCQIYEVLSVIRDIGAIAQVHAENGDIIAEEQQRILDLGITGPEGHVLSRPEEVEAEAVNRAITIANQTNCPLYITKVMSKSSAEVIAQARKKGTVVYGEPITASLGTDGSHYWSKNWAKAAAFVTSPPLSPDPTTPDFLNSLLSCGDLQVTGSAHCTFNTAQKAVGKDNFTLIPEGTNGTEERMSVIWDKAVVTGKMDENQFVAVTSTNAAKVFNLYPRKGRIAVGSDADLVIWDPDSVKTISAKTHNSSLEYNIFEGMECRGSPLVVISQGKIVLEDGTLHVTEGSGRYIPRKPFPDFVYKRIKARSRLAEL--RGVPRGLYDGPVCEVSVTPKTVT--------PASSAKTSPAKQQAPPV-----RNLHQSGFSLSGAQIDDNIPRRTTQRIVAPPGGRANITSL 571          
BLAST of Dihydropyrimidinase vs. Ensembl Human
Match: DPYSL2 (dihydropyrimidinase like 2 [Source:HGNC Symbol;Acc:HGNC:3014])

HSP 1 Score: 636.336 bits (1640), Expect = 0.000e+0
Identity = 303/578 (52.42%), Postives = 407/578 (70.42%), Query Frame = 1
Query:  133 HLQSSQNRLCIKGAKIVNDDRMFDADVYIEDGIIKQLGTNLVIPGGVRCVEANGKLLIPGGIDTHTHMEFPFMGTVSSDDFYSGTRAALAGGTTMIIDFVIGQKGTSLIDSYNQYREKADSKVCCDYGLHVIVSSYNESVGNEMEKLASEHGINSFKIFMAYKDSLMLEDDEMYEVFKKCKSIGALAQVHAENGKLIEKKSLELISKGITGPEGHLYSRPEEVECEATNRAIMLADQANCPLYVVHVMSKGAADIISDARRQGKVVFGEPIAAGLGTDGSHYSHSCWRHAAGYVMSPPLRNDRNTSKHLMQLLASGDLECTGTDHCVFKASQKALGKDDFRSIPNGVNGVEDRMSVIWEKGVVTGILDPCKFVAVTSTNAAKIFNIYPKKGRIDIGSDADLVLWNPDVRRTISASTHYQNVDFNIFEGMHCHGVAEMVISGGKVVLEDGNLRVAQGTGKFVPTNPFCNYVFNKVKLRDQCHKTLANKVERQPYDGPVEDLSKEMTNLNMNFDDDTDSQQNAISSEFVNTKRPLTSGGGRHMQDSSFALSGAQIDDNLPTRSGIRTRQPPGGTA--TSL 1860
            ++    +RL IKG KIVNDD+ F AD+Y+EDG+IKQ+G NL++PGGV+ +EA+ +++IPGGID HT  + P  G  S+DDF+ GT+AALAGGTTMIID V+ + GTSL+ +++Q+RE ADSK CCDY LHV +S +++ +  EME L  +HG+NSF ++MA+KD   L D ++YEV    + IGA+AQVHAENG +I ++   ++  GITGPEGH+ SRPEEVE EA NRAI +A+Q NCPLY+  VMSK +A++I+ AR++G VV+GEPI A LGTDGSHY    W  AA +V SPPL  D  T   L  LL+ GDL+ TG+ HC F  +QKA+GKD+F  IP G NG E+RMSVIW+K VVTG +D  +FVAVTSTNAAK+FN+YP+KGRI +GSDADLV+W+PD  +TISA TH  ++++NIFEGM C G   +VIS GK+VLEDG L V +G+G+++P  PF ++V+ ++K R +  +     V R  YDGPV ++S     +            +A +S       P+     R++  S F+LSGAQIDDN+P R+  R   PPGG A  TSL
Sbjct:  114 NINDQSDRLLIKGGKIVNDDQSFYADIYMEDGLIKQIGENLIVPGGVKTIEAHSRMVIPGGIDVHTRFQMPDQGMTSADDFFQGTKAALAGGTTMIIDHVVPEPGTSLLAAFDQWREWADSKSCCDYSLHVDISEWHKGIQEEMEALVKDHGVNSFLVYMAFKDRFQLTDCQIYEVLSVIRDIGAIAQVHAENGDIIAEEQQRILDLGITGPEGHVLSRPEEVEAEAVNRAITIANQTNCPLYITKVMSKSSAEVIAQARKKGTVVYGEPITASLGTDGSHYWSKNWAKAAAFVTSPPLSPDPTTPDFLNSLLSCGDLQVTGSAHCTFNTAQKAVGKDNFTLIPEGTNGTEERMSVIWDKAVVTGKMDENQFVAVTSTNAAKVFNLYPRKGRIAVGSDADLVIWDPDSVKTISAKTHNSSLEYNIFEGMECRGSPLVVISQGKIVLEDGTLHVTEGSGRYIPRKPFPDFVYKRIKARSRLAELRG--VPRGLYDGPVCEVSVTPKTVT--------PASSAKTSPAKQQAPPV-----RNLHQSGFSLSGAQIDDNIPRRTTQRIVAPPGGRANITSL 676          
BLAST of Dihydropyrimidinase vs. Ensembl Human
Match: DPYS (dihydropyrimidinase [Source:HGNC Symbol;Acc:HGNC:3013])

HSP 1 Score: 631.713 bits (1628), Expect = 0.000e+0
Identity = 304/508 (59.84%), Postives = 378/508 (74.41%), Query Frame = 1
Query:  142 SSQNRLCIKGAKIVNDDRMFDADVYIEDGIIKQLGTNLVIPGG----VRCVEANGKLLIPGGIDTHTHMEFPFMGTVSSDDFYSGTRAALAGGTTMIIDFVIGQKGTSLIDSYNQYREKADSKVCCDYGLHVIVSSYNESVGNEMEKLASEHGINSFKIFMAYKDSLMLEDDEMYEVFKKCKSIGALAQVHAENGKLIEKKSLELISKGITGPEGHLYSRPEEVECEATNRAIMLADQANCPLYVVHVMSKGAADIISDARRQGKVVFGEPIAAGLGTDGSHYSHSCWRHAAGYVMSPPLRNDRNTSKHLMQLLASGDLECTGTDHCVFKASQKALGKDDFRSIPNGVNGVEDRMSVIWEKGVVTGILDPCKFVAVTSTNAAKIFNIYPKKGRIDIGSDADLVLWNPDVRRTISASTHYQNVDFNIFEGMHCHGVAEMVISGGKVVLEDGNLRVAQGTGKFVPTNPFCNYVFNKVKLRDQ-CHKTLANKVERQPYDGPVEDLSKEMTN 1650
            ++ +RL I+G ++VNDD    ADV +EDG+++ LG +L+ PGG    +R ++A GKL++PGGIDTHTHM+FPFMG+ S DDF+ GT+AAL+GGTTMIIDF I QKG SLI+++  +R  AD KVCCDY LHV V+ +++ V  EM+ L  + G+NSFK+FMAYKD  M+ D E+YE F +CK IGA+AQVHAENG LI + + ++++ GITGPEGH   RPE VE EAT RAI +A   NCPLY+VHVMSK AA +I+DARR GKVV+GEPIAA LGTDG+HY +  W HAA +VM PPLR D +T   LM LLA+ DL  TGTD+C F   QKALGKDDF  IPNGVNGVEDRMSVIWEKGV +G +D  +FVAVTSTNAAKIFN+YP+KGRI +GSDAD+V+W+P   RTISA TH+Q V+FNIFEGM CHGV  + IS GKVV E G   V  G GKF+P  PF  Y++ ++K RD+ C  T    VER PY G V  L   +T 
Sbjct:    2 AAPSRLLIRGGRVVNDDFSEVADVLVEDGVVRALGHDLLPPGGAPAGLRVLDAAGKLVLPGGIDTHTHMQFPFMGSRSIDDFHQGTKAALSGGTTMIIDFAIPQKGGSLIEAFETWRSWADPKVCCDYSLHVAVTWWSDQVKEEMKILVQDKGVNSFKMFMAYKDLYMVTDLELYEAFSRCKEIGAIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIASAVNCPLYIVHVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNKEWHHAAHHVMGPPLRPDPSTPDFLMNLLANDDLTTTGTDNCTFNTCQKALGKDDFTKIPNGVNGVEDRMSVIWEKGVHSGKMDENRFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWDPKGTRTISAKTHHQAVNFNIFEGMVCHGVPLVTISRGKVVYEAGVFSVTAGDGKFIPRKPFAEYIYKRIKQRDRTCTPT---PVERAPYKGEVATLKSRVTK 506          
BLAST of Dihydropyrimidinase vs. Ensembl Human
Match: DPYSL3 (dihydropyrimidinase like 3 [Source:HGNC Symbol;Acc:HGNC:3015])

HSP 1 Score: 615.92 bits (1587), Expect = 0.000e+0
Identity = 296/578 (51.21%), Postives = 397/578 (68.69%), Query Frame = 1
Query:  112 GVKKVPLHLQSSQNRLCIKGAKIVNDDRMFDADVYIEDGIIKQLGTNLVIPGGVRCVEANGKLLIPGGIDTHTHMEFPFMGTVSSDDFYSGTRAALAGGTTMIIDFVIGQKGTSLIDSYNQYREKADSKVCCDYGLHVIVSSYNESVGNEMEKLASEHGINSFKIFMAYKDSLMLEDDEMYEVFKKCKSIGALAQVHAENGKLIEKKSLELISKGITGPEGHLYSRPEEVECEATNRAIMLADQANCPLYVVHVMSKGAADIISDARRQGKVVFGEPIAAGLGTDGSHYSHSCWRHAAGYVMSPPLRNDRNTSKHLMQLLASGDLECTGTDHCVFKASQKALGKDDFRSIPNGVNGVEDRMSVIWEKGVVTGILDPCKFVAVTSTNAAKIFNIYPKKGRIDIGSDADLVLWNPDVRRTISASTHYQNVDFNIFEGMHCHGVAEMVISGGKVVLEDGNLRVAQGTGKFVPTNPFCNYVFNKVKLRDQCHKTLANKVERQPYDGPVEDLSKEMTNLNMNFDDDTDSQQNAISSEFVNTKRPLTSGGGRHMQDSSFALSGAQIDDNLPTRSGIRTRQPPGG 1845
            G K +P   + + +RL IKG +IVNDD+ F AD+Y+EDG+IKQ+G NL++PGGV+ +EANGK++IPGGID HTH + P+ G  + DDF+ GT+AALAGGTTMIID V+ +  +SL ++Y ++RE AD K CCDY LHV ++ +N+SV  E++ L  + G+NSF ++MAYKD   + + E+YE+F     +GA+AQVHAENG +I ++   ++  GITGPEGH+ SRPEE+E EA  RAI +A Q NCPLYV  VMSK AAD+IS AR++G VVFGEPI A LG DG+HY    W  AA +V SPPL  D  T  ++  LLASGDL+ +G+ HC F  +QKA+GKD+F +IP G NGVE+RMSVIW+K V TG +D  +FVAVTSTNAAKIFN+YP+KGRI +GSD+DLV+W+PD  + +SA  H    ++NIFEGM   G   +VI  GK++LEDGNL V QG G+F+P +PF +YV+ ++K R +     A  V R  YDGPV DL+             T        S   +  RP  +   R++  S F+LSG Q+D+ + + S  R   PPGG
Sbjct:    5 GKKNIP---RITSDRLLIKGGRIVNDDQSFYADIYMEDGLIKQIGDNLIVPGGVKTIEANGKMVIPGGIDVHTHFQMPYKGMTTVDDFFQGTKAALAGGTTMIIDHVVPEPESSLTEAYEKWREWADGKSCCDYALHVDITHWNDSVKQEVQNLIKDKGVNSFMVYMAYKDLYQVSNTELYEIFTCLGELGAIAQVHAENGDIIAQEQTRMLEMGITGPEGHVLSRPEELEAEAVFRAITIASQTNCPLYVTKVMSKSAADLISQARKKGNVVFGEPITASLGIDGTHYWSKNWAKAAAFVTSPPLSPDPTTPDYINSLLASGDLQLSGSAHCTFSTAQKAIGKDNFTAIPEGTNGVEERMSVIWDKAVATGKMDENQFVAVTSTNAAKIFNLYPRKGRISVGSDSDLVIWDPDAVKIVSAKNHQSAAEYNIFEGMELRGAPLVVICQGKIMLEDGNLHVTQGAGRFIPCSPFSDYVYKRIKARRKMADLHA--VPRGMYDGPVFDLTT------------TPKGGTPAGSARGSPTRP--NPPVRNLHQSGFSLSGTQVDEGVRSASK-RIVAPPGG 562          
BLAST of Dihydropyrimidinase vs. Ensembl Human
Match: DPYSL3 (dihydropyrimidinase like 3 [Source:HGNC Symbol;Acc:HGNC:3015])

HSP 1 Score: 613.994 bits (1582), Expect = 0.000e+0
Identity = 294/572 (51.40%), Postives = 393/572 (68.71%), Query Frame = 1
Query:  130 LHLQSSQNRLCIKGAKIVNDDRMFDADVYIEDGIIKQLGTNLVIPGGVRCVEANGKLLIPGGIDTHTHMEFPFMGTVSSDDFYSGTRAALAGGTTMIIDFVIGQKGTSLIDSYNQYREKADSKVCCDYGLHVIVSSYNESVGNEMEKLASEHGINSFKIFMAYKDSLMLEDDEMYEVFKKCKSIGALAQVHAENGKLIEKKSLELISKGITGPEGHLYSRPEEVECEATNRAIMLADQANCPLYVVHVMSKGAADIISDARRQGKVVFGEPIAAGLGTDGSHYSHSCWRHAAGYVMSPPLRNDRNTSKHLMQLLASGDLECTGTDHCVFKASQKALGKDDFRSIPNGVNGVEDRMSVIWEKGVVTGILDPCKFVAVTSTNAAKIFNIYPKKGRIDIGSDADLVLWNPDVRRTISASTHYQNVDFNIFEGMHCHGVAEMVISGGKVVLEDGNLRVAQGTGKFVPTNPFCNYVFNKVKLRDQCHKTLANKVERQPYDGPVEDLSKEMTNLNMNFDDDTDSQQNAISSEFVNTKRPLTSGGGRHMQDSSFALSGAQIDDNLPTRSGIRTRQPPGG 1845
            L  +   +RL IKG +IVNDD+ F AD+Y+EDG+IKQ+G NL++PGGV+ +EANGK++IPGGID HTH + P+ G  + DDF+ GT+AALAGGTTMIID V+ +  +SL ++Y ++RE AD K CCDY LHV ++ +N+SV  E++ L  + G+NSF ++MAYKD   + + E+YE+F     +GA+AQVHAENG +I ++   ++  GITGPEGH+ SRPEE+E EA  RAI +A Q NCPLYV  VMSK AAD+IS AR++G VVFGEPI A LG DG+HY    W  AA +V SPPL  D  T  ++  LLASGDL+ +G+ HC F  +QKA+GKD+F +IP G NGVE+RMSVIW+K V TG +D  +FVAVTSTNAAKIFN+YP+KGRI +GSD+DLV+W+PD  + +SA  H    ++NIFEGM   G   +VI  GK++LEDGNL V QG G+F+P +PF +YV+ ++K R +     A  V R  YDGPV DL+             T        S   +  RP  +   R++  S F+LSG Q+D+ + + S  R   PPGG
Sbjct:  122 LGPKDKSDRLLIKGGRIVNDDQSFYADIYMEDGLIKQIGDNLIVPGGVKTIEANGKMVIPGGIDVHTHFQMPYKGMTTVDDFFQGTKAALAGGTTMIIDHVVPEPESSLTEAYEKWREWADGKSCCDYALHVDITHWNDSVKQEVQNLIKDKGVNSFMVYMAYKDLYQVSNTELYEIFTCLGELGAIAQVHAENGDIIAQEQTRMLEMGITGPEGHVLSRPEELEAEAVFRAITIASQTNCPLYVTKVMSKSAADLISQARKKGNVVFGEPITASLGIDGTHYWSKNWAKAAAFVTSPPLSPDPTTPDYINSLLASGDLQLSGSAHCTFSTAQKAIGKDNFTAIPEGTNGVEERMSVIWDKAVATGKMDENQFVAVTSTNAAKIFNLYPRKGRISVGSDSDLVIWDPDAVKIVSAKNHQSAAEYNIFEGMELRGAPLVVICQGKIMLEDGNLHVTQGAGRFIPCSPFSDYVYKRIKARRKMADLHA--VPRGMYDGPVFDLTT------------TPKGGTPAGSARGSPTRP--NPPVRNLHQSGFSLSGTQVDEGVRSASK-RIVAPPGG 676          
BLAST of Dihydropyrimidinase vs. Ensembl Celegans
Match: dhp-2 (Dihydropyrimidinase 2 [Source:UniProtKB/Swiss-Prot;Acc:Q18677])

HSP 1 Score: 574.318 bits (1479), Expect = 0.000e+0
Identity = 274/487 (56.26%), Postives = 351/487 (72.07%), Query Frame = 1
Query:  157 LCIKGAKIVNDDRMFDADVYIEDGIIKQLGTNLVIPGGVRCVEANGKLLIPGGIDTHTHMEFPFMGTVSSDDFYSGTRAALAGGTTMIIDFVIGQKGTSLIDSYNQYREKADSKVCCDYGLHVIVSSYNESVGNEMEKLA-SEHGINSFKIFMAYKDSLMLEDDEMYEVFKKCKSIGALAQVHAENGKLIEKKSLELISKGITGPEGHLYSRPEEVECEATNRAIMLADQANCPLYVVHVMSKGAADIISDARRQGKVVFGEPIAAGLGTDGSHYSHSCWRHAAGYVMSPPLRNDRNTSKHLMQLLASGDLECTGTDHCVFKASQKALGKDDFRSIPNGVNGVEDRMSVIWEKGVVTGILDPCKFVAVTSTNAAKIFNIYPKKGRIDIGSDADLVLWNPDVRRTISASTHYQNVDFNIFEGMHCHGVAEMVISGGKVVLEDGNLRVAQGTGKFVPTNPFCNYVFNKVKLRDQCHKTLANKVERQPYD 1614
            L IK   IVNDD +F +DV + DG I ++  ++    G+  V+A  +L+IPGGID HTHM+ PFMG ++ DDF+ GT AA+AGGTTMIIDFVI  KG SL+ +Y+++R  AD KV CDYGL + ++S+   +  EME +  +E+GINSFK F+AY    M+ D+E Y+   +C  + ALA+VHAENG +I ++   L+S GITGPEGH  SRPEE+E EAT RA  +A QANCPLYVVHVMSKGAA  I+  R++G VVFGEPIAAGL TDGSHY +  W HAA YVMSPPL  D +T   LM+LLA+G+L  T TD+C F   QK+LGKDDF  IPNGVNGVEDRMSV+W+KGV  GI+DP +FVAVTST AAKIFN YP+KGRI +GSDAD+V+WN +  RTIS  TH+  +DFNIFEGM  HGV E+ IS G+ V  +G L+  QG+G+F+P  P    VF+ V  R +  + +  K++R PY+
Sbjct:    3 LLIKNGTIVNDDAIFKSDVLVLDGRIVEIAPSIQPTPGLEVVDATDRLVIPGGIDPHTHMQLPFMGEIAKDDFHRGTEAAVAGGTTMIIDFVIPTKGESLLVAYDRWRGWADPKVVCDYGLSMAITSWGPEIAKEMEIVTGAEYGINSFKFFLAYAGVFMVRDEEFYQGMIQCAKLRALARVHAENGSVIAERCEHLLSSGITGPEGHTQSRPEELEAEATFRACTMASQANCPLYVVHVMSKGAAAAIAHHRKKGAVVFGEPIAAGLATDGSHYYNEDWLHAARYVMSPPLSRDPSTPSALMKLLAAGELHLTATDNCTFDCQQKSLGKDDFTKIPNGVNGVEDRMSVVWDKGVHAGIIDPMRFVAVTSTMAAKIFNCYPQKGRIAVGSDADIVIWNANATRTISKDTHHHAIDFNIFEGMQVHGVPEITISRGRTVWANGQLKTVQGSGQFIPLAPDSQIVFSAVDNRKKAMEPV--KIDRIPYE 487          
BLAST of Dihydropyrimidinase vs. Ensembl Celegans
Match: dhp-1 (Dihydropyrimidinase 1 [Source:UniProtKB/Swiss-Prot;Acc:Q21773])

HSP 1 Score: 563.148 bits (1450), Expect = 0.000e+0
Identity = 266/485 (54.85%), Postives = 353/485 (72.78%), Query Frame = 1
Query:  157 LCIKGAKIVNDDRMFDADVYIEDGIIKQLGTNLVIPGGVRCVEANGKLLIPGGIDTHTHMEFPFMGTVSSDDFYSGTRAALAGGTTMIIDFVIG--QKGTSLIDSYNQYREKADSKVCCDYGLHVIVSSYNESVGNEMEKLAS-EHGINSFKIFMAYKDSLMLEDDEMYEVFKKCKSIGALAQVHAENGKLIEKKSLELISKGITGPEGHLYSRPEEVECEATNRAIMLADQANCPLYVVHVMSKGAADIISDARRQGKVVFGEPIAAGLGTDGSHYSHSCWRHAAGYVMSPPLRNDRNTSKHLMQLLASGDLECTGTDHCVFKASQKALGKDDFRSIPNGVNGVEDRMSVIWEKGVVTGILDPCKFVAVTSTNAAKIFNIYPKKGRIDIGSDADLVLWNPDVRRTISASTHYQNVDFNIFEGMHCHGVAEMVISGGKVVLEDGNLRVAQGTGKFVPTNPFCNYVFNKVKLRDQCHKTLANKVER 1602
            L IK   +VN+D MF ADV + +GII ++  N+        ++A  +L+IPGGID HTHM+ P+MG V+ DDF  GT AA+AGGTTMIIDF     + G SLI  YN++R  AD KVCCDYGL V ++ +      +M  + S E G+NSFK +MAY+++LM+ DDE++   ++C  + ALA+VH ENG +I++K ++L++KG+TGPEGH  SRPEE+E EATNRA +LA QANCP+Y+VHVM+KGAA  IS  R QG +VFGEPIAAGL  DGSHY +  W HAA YVMSPPL  D  T + LM+LLA+G+L  TGTD+C +   QK+LGK +F  IPNG+NGVEDRMSV+WEKGV +GI+DP ++V++TS+ AAKIFNIYP+KGRI +GSDAD+V++NP+  RTIS  TH+ N+DFNIFEG++CHGVAE+ IS G++V   G L+   G+GKF+P      +VF+  + R+Q  K     VER
Sbjct:    5 LVIKNGTVVNEDGMFKADVLVRNGIIVEVSPNITALPDTEVIDATDRLVIPGGIDPHTHMQMPYMGEVTKDDFLKGTEAAVAGGTTMIIDFCCPDHRNGESLIAGYNRWRSWADPKVCCDYGLSVAITMWRPETAEQMAIITSPEFGVNSFKFYMAYENTLMVRDDELFRGMQECAKLRALARVHCENGSVIKEKEIDLLAKGVTGPEGHTQSRPEEIEAEATNRACVLAAQANCPVYIVHVMTKGAASAISHHRAQGSIVFGEPIAAGLALDGSHYYNEDWLHAARYVMSPPLSRDPTTPELLMKLLAAGELHLTGTDNCTYDCRQKSLGKGNFTKIPNGINGVEDRMSVVWEKGVHSGIIDPMRYVSITSSTAAKIFNIYPRKGRIAVGSDADIVIFNPNATRTISKDTHHHNLDFNIFEGINCHGVAEVTISRGRIVWAHGKLQTVPGSGKFIPLLANSPFVFSTHEKREQ--KIQPRIVER 487          
BLAST of Dihydropyrimidinase vs. Ensembl Celegans
Match: dhp-1 (Dihydropyrimidinase 1 [Source:UniProtKB/Swiss-Prot;Acc:Q21773])

HSP 1 Score: 563.148 bits (1450), Expect = 0.000e+0
Identity = 266/485 (54.85%), Postives = 353/485 (72.78%), Query Frame = 1
Query:  157 LCIKGAKIVNDDRMFDADVYIEDGIIKQLGTNLVIPGGVRCVEANGKLLIPGGIDTHTHMEFPFMGTVSSDDFYSGTRAALAGGTTMIIDFVIG--QKGTSLIDSYNQYREKADSKVCCDYGLHVIVSSYNESVGNEMEKLAS-EHGINSFKIFMAYKDSLMLEDDEMYEVFKKCKSIGALAQVHAENGKLIEKKSLELISKGITGPEGHLYSRPEEVECEATNRAIMLADQANCPLYVVHVMSKGAADIISDARRQGKVVFGEPIAAGLGTDGSHYSHSCWRHAAGYVMSPPLRNDRNTSKHLMQLLASGDLECTGTDHCVFKASQKALGKDDFRSIPNGVNGVEDRMSVIWEKGVVTGILDPCKFVAVTSTNAAKIFNIYPKKGRIDIGSDADLVLWNPDVRRTISASTHYQNVDFNIFEGMHCHGVAEMVISGGKVVLEDGNLRVAQGTGKFVPTNPFCNYVFNKVKLRDQCHKTLANKVER 1602
            L IK   +VN+D MF ADV + +GII ++  N+        ++A  +L+IPGGID HTHM+ P+MG V+ DDF  GT AA+AGGTTMIIDF     + G SLI  YN++R  AD KVCCDYGL V ++ +      +M  + S E G+NSFK +MAY+++LM+ DDE++   ++C  + ALA+VH ENG +I++K ++L++KG+TGPEGH  SRPEE+E EATNRA +LA QANCP+Y+VHVM+KGAA  IS  R QG +VFGEPIAAGL  DGSHY +  W HAA YVMSPPL  D  T + LM+LLA+G+L  TGTD+C +   QK+LGK +F  IPNG+NGVEDRMSV+WEKGV +GI+DP ++V++TS+ AAKIFNIYP+KGRI +GSDAD+V++NP+  RTIS  TH+ N+DFNIFEG++CHGVAE+ IS G++V   G L+   G+GKF+P      +VF+  + R+Q  K     VER
Sbjct:    5 LVIKNGTVVNEDGMFKADVLVRNGIIVEVSPNITALPDTEVIDATDRLVIPGGIDPHTHMQMPYMGEVTKDDFLKGTEAAVAGGTTMIIDFCCPDHRNGESLIAGYNRWRSWADPKVCCDYGLSVAITMWRPETAEQMAIITSPEFGVNSFKFYMAYENTLMVRDDELFRGMQECAKLRALARVHCENGSVIKEKEIDLLAKGVTGPEGHTQSRPEEIEAEATNRACVLAAQANCPVYIVHVMTKGAASAISHHRAQGSIVFGEPIAAGLALDGSHYYNEDWLHAARYVMSPPLSRDPTTPELLMKLLAAGELHLTGTDNCTYDCRQKSLGKGNFTKIPNGINGVEDRMSVVWEKGVHSGIIDPMRYVSITSSTAAKIFNIYPRKGRIAVGSDADIVIFNPNATRTISKDTHHHNLDFNIFEGINCHGVAEVTISRGRIVWAHGKLQTVPGSGKFIPLLANSPFVFSTHEKREQ--KIQPRIVER 487          
BLAST of Dihydropyrimidinase vs. Ensembl Celegans
Match: dhp-1 (Dihydropyrimidinase 1 [Source:UniProtKB/Swiss-Prot;Acc:Q21773])

HSP 1 Score: 563.148 bits (1450), Expect = 0.000e+0
Identity = 266/485 (54.85%), Postives = 353/485 (72.78%), Query Frame = 1
Query:  157 LCIKGAKIVNDDRMFDADVYIEDGIIKQLGTNLVIPGGVRCVEANGKLLIPGGIDTHTHMEFPFMGTVSSDDFYSGTRAALAGGTTMIIDFVIG--QKGTSLIDSYNQYREKADSKVCCDYGLHVIVSSYNESVGNEMEKLAS-EHGINSFKIFMAYKDSLMLEDDEMYEVFKKCKSIGALAQVHAENGKLIEKKSLELISKGITGPEGHLYSRPEEVECEATNRAIMLADQANCPLYVVHVMSKGAADIISDARRQGKVVFGEPIAAGLGTDGSHYSHSCWRHAAGYVMSPPLRNDRNTSKHLMQLLASGDLECTGTDHCVFKASQKALGKDDFRSIPNGVNGVEDRMSVIWEKGVVTGILDPCKFVAVTSTNAAKIFNIYPKKGRIDIGSDADLVLWNPDVRRTISASTHYQNVDFNIFEGMHCHGVAEMVISGGKVVLEDGNLRVAQGTGKFVPTNPFCNYVFNKVKLRDQCHKTLANKVER 1602
            L IK   +VN+D MF ADV + +GII ++  N+        ++A  +L+IPGGID HTHM+ P+MG V+ DDF  GT AA+AGGTTMIIDF     + G SLI  YN++R  AD KVCCDYGL V ++ +      +M  + S E G+NSFK +MAY+++LM+ DDE++   ++C  + ALA+VH ENG +I++K ++L++KG+TGPEGH  SRPEE+E EATNRA +LA QANCP+Y+VHVM+KGAA  IS  R QG +VFGEPIAAGL  DGSHY +  W HAA YVMSPPL  D  T + LM+LLA+G+L  TGTD+C +   QK+LGK +F  IPNG+NGVEDRMSV+WEKGV +GI+DP ++V++TS+ AAKIFNIYP+KGRI +GSDAD+V++NP+  RTIS  TH+ N+DFNIFEG++CHGVAE+ IS G++V   G L+   G+GKF+P      +VF+  + R+Q  K     VER
Sbjct:    5 LVIKNGTVVNEDGMFKADVLVRNGIIVEVSPNITALPDTEVIDATDRLVIPGGIDPHTHMQMPYMGEVTKDDFLKGTEAAVAGGTTMIIDFCCPDHRNGESLIAGYNRWRSWADPKVCCDYGLSVAITMWRPETAEQMAIITSPEFGVNSFKFYMAYENTLMVRDDELFRGMQECAKLRALARVHCENGSVIKEKEIDLLAKGVTGPEGHTQSRPEEIEAEATNRACVLAAQANCPVYIVHVMTKGAASAISHHRAQGSIVFGEPIAAGLALDGSHYYNEDWLHAARYVMSPPLSRDPTTPELLMKLLAAGELHLTGTDNCTYDCRQKSLGKGNFTKIPNGINGVEDRMSVVWEKGVHSGIIDPMRYVSITSSTAAKIFNIYPRKGRIAVGSDADIVIFNPNATRTISKDTHHHNLDFNIFEGINCHGVAEVTISRGRIVWAHGKLQTVPGSGKFIPLLANSPFVFSTHEKREQ--KIQPRIVER 487          
BLAST of Dihydropyrimidinase vs. Ensembl Celegans
Match: unc-33 (pep chromosome:WBcel235:IV:3518147:3525572:1 gene:WBGene00006769.1 transcript:Y37E11C.1b.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:unc-33)

HSP 1 Score: 301.982 bits (772), Expect = 1.034e-92
Identity = 191/573 (33.33%), Postives = 297/573 (51.83%), Query Frame = 1
Query:  157 LCIKGAKIVNDDRMFDADVYIEDGIIKQLGTNLVIPGGVRCVEANGKLLIPGGIDTHTHMEFPFMGTVSSDDFYSGTRAALAGGTTMIIDFVIGQKGTSLIDSYNQYREKAD-SKVCCDYGLHVIVSSYNESVGNEMEKLASEHGINSFKIFMAYKDSLMLEDDEMYEVFKKCKSIGALAQVHAENGKLI---EKKSLELISKGITGPEGHLYSRPEEVECEATNRAIMLADQANCPLYVVHVMSKGAADIISDARRQGKVVFGEPIAAGLGTDGSHYSHSCWRHAAGYVMSPPLRNDRNTSKHLMQLLASGDLECTGTDHCVFKASQKALGKDDFRSIPNGVNGVEDRMSVIWEKGVVTGILDPCKFVAVTSTNAAKIFNIYPKKGRIDIGSDADLVLWNPDVRRTISASTHYQNVDFNIFEGMHCHGVAEMVISGGKVVLEDGNLRVAQGTGKFVPTNPFCNYVFNKVKLRDQCHKTLANKVERQPYDGPVEDLSKEMTNLNMNFDDDTDSQQNAISSEFVNTKRPLTSGGGRHMQDSSFALSGAQIDDNLPTRSGIRTRQPPGGTATSLW 1863
            L +K A+IVNDD +F AD+ IEDGII+ +  NL  P G   ++A GKL +P GID +T +        S DD  +G ++A+AGGT  I++ V  +   S++ +  + + + + S + C   L V ++ + E    EM +L    GINSF +     D + L DD++ E+F+  K +GAL +V  EN  ++   EKK L+L   G+TGPEG   SRPE +E +  +   +L + A+CP+ +V V S  +   I  AR  G +   E  +A +  DGS       R A+ ++   PLR  R     ++  L++  L    + H    ++ +   KD F     G  G E+RM+V+WE+ V +G +D  +FVAVTSTNAAK+FN+YPKKGRI +G+DADLV+W+   +R + +S    + + ++++G+  H V    I GGK+  ++G +R A   G F+  +P   Y+F+ V  RD+     AN          VE + +E ++           QQN       +  R  T      + +SS    G+  +         R R PPGG  T  W
Sbjct:  160 LLVKNAQIVNDDAIFVADILIEDGIIQNVAPNLEAPEGAEVLDAAGKLALPAGIDVYTQVT-----DSSVDDLSTGCKSAIAGGTGTIVEVVRPRGAESVVSAVKRVKNQLEKSGISCHVALSVAITDFCE---QEMSELVKNEGINSFVL-----DGVSLTDDKLLELFEHVKRLGALIRVVPENKSIVAMLEKKMLKL---GVTGPEGFPQSRPESLEADRVSGVCVLGNLASCPISIVQVSSADSLAAIEKARASGALAHAEIASAAVTADGSALFSQDLRFASAHLTDVPLR--RGAPDRMIGALSTQPLVVCTSGHRPVNSATRVAAKD-FAIAQKGSTGAEERMAVVWERAVRSGRIDAMRFVAVTSTNAAKMFNMYPKKGRIAVGADADLVIWDASGKRVLESSRAQSSQENSMYDGLTVHSVVTATIVGGKIAYQNGEVREAPVAGGFLRLSPNSPYLFSMVGQRDK----FAN----------VERVEREASSQQQK------PQQNGHHKNSGDFDRNRT-----KVMESSIDFGGSAAN---------RPRNPPGGRTTGFW 679          
BLAST of Dihydropyrimidinase vs. Ensembl Fly
Match: CRMP (gene:FBgn0023023 transcript:FBtr0114453)

HSP 1 Score: 598.971 bits (1543), Expect = 0.000e+0
Identity = 304/599 (50.75%), Postives = 406/599 (67.78%), Query Frame = 1
Query:  115 VKKVPLHLQSSQNRLCIKGAKIVNDDRMFDADVYIEDGIIKQLG--TNLVIPGGVRCVEANGKLLIPGGIDTHTHMEFPFMGTVSSDDFYSGTRAALAGGTTMIIDFVIGQKGTSLIDSYNQYREKADSKVCCDYGLHVIVSSYNESVGNEMEKLASEHGINSFKIFMAYKDSLMLEDDEMYEVFKKCKSIGALAQVHAENGKLIEKKSLELISKGITGPEGHLYSRPEEVECEATNRAIMLADQANCPLYVVHVMSKGAADIISDARRQ--GKVVFGEPIAAGLGTDGSHYSHSCWRHAAGYVMSPPLRNDRNTSKHLMQLLASGDLECTGTDHCVFKASQKALGKDDFRSIPNGVNGVEDRMSVIWEKGVVTGILDPCKFVAVTSTNAAKIFNIYPKKGRIDIGSDADLVLWNPDVRRTISASTHYQNVDFNIFEGMHCHGVAEMVISGGKVVLEDGNLRVAQGTGKFVPTNPFCNYVFNKVKLRDQCHKTLANKVERQPYDGPVEDLSKEMTNLNMNFDDDTDSQQN---------AISSEFVNTKRPLTSG---GGRHMQDSSFALSGAQIDDNLPTRSGIRTRQPPGGTATSLW 1863
            VKKVP+HLQS+QNR+ IK  +IVN D+ F ADVYIEDGIIK +G  + + IPGGVR ++A+G ++IPGGID HTHM+ PF G V+ DDFY GT+AA+AGGTTMIIDFV+  K  S+I++Y+++R  AD KVCCDYGLHV ++ +++SV  E+  L  E G+NSFK FMAYK    L D ++ +VF++ + +  +A VHAENG +I K +  L+++GI GPEGH  SRPEEVE EA +RA +LA QA+CPLYVVHVMSK A   ++ AR +  G+ + GE +AA LGTD +   H  +   A +V+SPPLR D+ T + LM+LLA+ DL+ TG+D+C F    KALGK DF  IPNGVNGVEDRMS++WEKGV  G+LDPC+FVAVTSTNAAKIFNIYP+KGRI +GSDAD+V+WNP+  RTIS  TH+   DFNIFEGM  HGV E V+  G++  E GN+RVA+G G+F+PT     +V++ ++           KV+ QP +   E  +  M       D     Q+          A+ +E      P   G   G R +Q+SSF++S  +  D    R+ I+ + PPGG ++  W
Sbjct:    8 VKKVPIHLQSAQNRVYIKNGEIVNHDKSFKADVYIEDGIIKFVGPSSEITIPGGVRTIDASGLMIIPGGIDPHTHMQLPFGGAVAVDDFYHGTKAAVAGGTTMIIDFVLPNKHESMIEAYDKWRSWADPKVCCDYGLHVGITWWSKSVSEEIGILCKELGVNSFKTFMAYKGLYQLNDSDLLDVFERIRHLNGVAMVHAENGDIIAKNTQRLLAEGINGPEGHELSRPEEVEAEAVHRACVLAHQADCPLYVVHVMSKSAGIELARARHRYRGRYIMGETLAAALGTDATCCQHLGFDAEAAHVLSPPLRPDKTTPEFLMKLLANDDLQLTGSDNCTFNKEHKALGKGDFTKIPNGVNGVEDRMSLVWEKGVHAGLLDPCRFVAVTSTNAAKIFNIYPQKGRIAVGSDADIVIWNPNATRTISKDTHHHACDFNIFEGMTVHGVCEFVLVRGRICAERGNVRVAEGFGRFIPTPVRPPFVYDIIE----------GKVQSQPEEQHEEKQNGSMAKRFAELDIQIPVQEPISAMLAGNLAMPAEGSLCSTPSVRGRVDGKRDLQESSFSIS--EELDRSGVRACIKVKNPPGGKSSGFW 594          
BLAST of Dihydropyrimidinase vs. Ensembl Fly
Match: CRMP (gene:FBgn0023023 transcript:FBtr0089686)

HSP 1 Score: 571.622 bits (1472), Expect = 0.000e+0
Identity = 293/597 (49.08%), Postives = 393/597 (65.83%), Query Frame = 1
Query:  115 VKKVPLHLQSSQNRLCIKGAKIVNDDRMFDADVYIEDGIIKQLG--TNLVIPGGVRCVEANGKLLIPGGIDTHTHMEFPFMGTVSSDDFYSGTRAALAGGTTMIIDFVIGQKGTSLIDSYNQYREKADSKVCCDYGLHVIVSSYNESVGNEMEKLASEHGINSFKIFMAYKDSLMLEDDEMYEVFKKCKSIGALAQVHAENGKLIEKKSLELISKGITGPEGHLYSRPEEVECEATNRAIMLADQANCPLYVVHVMSKGAADIISDARRQGKVVFGEPIAAGLGTDGSHYSHSCWRHAAGYVMSPPLRNDRNTSKHLMQLLASGDLECTGTDHCVFKASQKALGKDDFRSIPNGVNGVEDRMSVIWEKGVVTGILDPCKFVAVTSTNAAKIFNIYPKKGRIDIGSDADLVLWNPDVRRTISASTHYQNVDFNIFEGMHCHGVAEMVISGGKVVLEDGNLRVAQGTGKFVPTNPFCNYVFNKVKLRDQCHKTLANKVERQPYDGPVEDLSKEMTNLNMNFDDDTDSQQN---------AISSEFVNTKRPLTSG---GGRHMQDSSFALSGAQIDDNLPTRSGIRTRQPPGGTATSLW 1863
            VKKVP+HLQS+QNR+ IK  +IVN D+ F ADVYIEDGIIK +G  + + IPGGVR ++A+G ++IPGGID HTHM+ PF G V+ DDFY GT+AA+AGGTTMIIDFV+  K  S+I++Y+++R  AD KVCCDYGLHV ++ +++SV  E+  L  E G+NSFK FMAYK    L D ++ +VF++ + +  +A VHAENG +I K +  L+++GI GPEGH  SRPEEVE EA +RA +LA Q   PL+V  + SK +A+++  ARR G  VFGE +A+ LG   S        +A   + SPP+R    T + LM+ LA  DL+ TG+D+C F    KALGK DF  IPNGVNGVEDRMS++WEKGV  G+LDPC+FVAVTSTNAAKIFNIYP+KGRI +GSDAD+V+WNP+  RTIS  TH+   DFNIFEGM  HGV E V+  G++  E GN+RVA+G G+F+PT     +V++ ++           KV+ QP +   E  +  M       D     Q+          A+ +E      P   G   G R +Q+SSF++S  +  D    R+ I+ + PPGG ++  W
Sbjct:    8 VKKVPIHLQSAQNRVYIKNGEIVNHDKSFKADVYIEDGIIKFVGPSSEITIPGGVRTIDASGLMIIPGGIDPHTHMQLPFGGAVAVDDFYHGTKAAVAGGTTMIIDFVLPNKHESMIEAYDKWRSWADPKVCCDYGLHVGITWWSKSVSEEIGILCKELGVNSFKTFMAYKGLYQLNDSDLLDVFERIRHLNGVAMVHAENGDIIAKNTQRLLAEGINGPEGHELSRPEEVEAEAVHRACVLAHQMKTPLFVSGLTSKSSAELVGRARRSGYCVFGETLASSLGRSMSAVPKGDRIYA---ITSPPIRESAETPRQLMKSLAYDDLQLTGSDNCTFNKEHKALGKGDFTKIPNGVNGVEDRMSLVWEKGVHAGLLDPCRFVAVTSTNAAKIFNIYPQKGRIAVGSDADIVIWNPNATRTISKDTHHHACDFNIFEGMTVHGVCEFVLVRGRICAERGNVRVAEGFGRFIPTPVRPPFVYDIIE----------GKVQSQPEEQHEEKQNGSMAKRFAELDIQIPVQEPISAMLAGNLAMPAEGSLCSTPSVRGRVDGKRDLQESSFSIS--EELDRSGVRACIKVKNPPGGKSSGFW 589          
BLAST of Dihydropyrimidinase vs. Ensembl Fly
Match: CRMP (gene:FBgn0023023 transcript:FBtr0089685)

HSP 1 Score: 363.614 bits (932), Expect = 1.021e-120
Identity = 178/324 (54.94%), Postives = 238/324 (73.46%), Query Frame = 1
Query:  115 VKKVPLHLQSSQNRLCIKGAKIVNDDRMFDADVYIEDGIIKQLG--TNLVIPGGVRCVEANGKLLIPGGIDTHTHMEFPFMGTVSSDDFYSGTRAALAGGTTMIIDFVIGQKGTSLIDSYNQYREKADSKVCCDYGLHVIVSSYNESVGNEMEKLASEHGINSFKIFMAYKDSLMLEDDEMYEVFKKCKSIGALAQVHAENGKLIEKKSLELISKGITGPEGHLYSRPEEVECEATNRAIMLADQANCPLYVVHVMSKGAADIISDARR--QGKVVFGEPIAAGLGTDGSHYSHSCWRHAAGYVMSPPLRNDRNTSKHLMQLLA 1074
            VKKVP+HLQS+QNR+ IK  +IVN D+ F ADVYIEDGIIK +G  + + IPGGVR ++A+G ++IPGGID HTHM+ PF G V+ DDFY GT+AA+AGGTTMIIDFV+  K  S+I++Y+++R  AD KVCCDYGLHV ++ +++SV  E+  L  E G+NSFK FMAYK    L D ++ +VF++ + +  +A VHAENG +I K +  L+++GI GPEGH  SRPEEVE EA +RA +LA QA+CPLYVVHVMSK A   ++ AR   +G+ + GE +AA LGTD +   H  +   A +V+SPPLR D+ T + LM+LLA
Sbjct:    8 VKKVPIHLQSAQNRVYIKNGEIVNHDKSFKADVYIEDGIIKFVGPSSEITIPGGVRTIDASGLMIIPGGIDPHTHMQLPFGGAVAVDDFYHGTKAAVAGGTTMIIDFVLPNKHESMIEAYDKWRSWADPKVCCDYGLHVGITWWSKSVSEEIGILCKELGVNSFKTFMAYKGLYQLNDSDLLDVFERIRHLNGVAMVHAENGDIIAKNTQRLLAEGINGPEGHELSRPEEVEAEAVHRACVLAHQADCPLYVVHVMSKSAGIELARARHRYRGRYIMGETLAAALGTDATCCQHLGFDAEAAHVLSPPLRPDKTTPEFLMKLLA 331          
BLAST of Dihydropyrimidinase vs. Ensembl Fly
Match: CG6106 (gene:FBgn0030914 transcript:FBtr0343296)

HSP 1 Score: 62.3882 bits (150), Expect = 7.147e-10
Identity = 52/237 (21.94%), Postives = 91/237 (38.40%), Query Frame = 1
Query:  778 LYSRPEEVECEATNRAIMLADQANCPLYVVHVMSKGAAD---IISDARRQGKVVFGEPIAAGLGTDGSHYSHSCWRHAAGYVMSPPLRNDRNTSKHLMQLLASGDLECTGTDHCVFKASQKAL----GKDDFRSIPNGVNGVEDRMSVIWEKGV---VTGILDPCKFVAVTSTNAAKIFNIYPKKGRIDIGSDADLVLWNPDVRRTISASTHYQNVDFNIFEGMHCHGVAEMVISGG 1458
            L +RP ++E  AT     LA++   P   +H+++  + +   ++ + RRQG  +  +     L                 +   PP+R  RN  +    L   G +   G+DH       +AL    G+ +F     G+N ++  +SV+W        +  L       +     A +  +   KGRI  G DAD  +W+P+   T+     Y       + G    GV    +  G
Sbjct:  224 LVTRPPQMEISATQLLCRLANRH--PRRCIHILNCSSGESLPLVEECRRQGGNLTVDTCPHYLALAAEDVPDC----GTEFKTWPPIRERRNQEQLWQALRPGGAIRMIGSDHSPATPGARALTCGRGRGNFLKAWPGINSLQLSLSVVWTAAANRRGSANLTIADIHRLMCQEPANLCGLSASKGRIAEGYDADFCVWSPEEEFTVGPELLYTATKATPYAGQKLRGVVHATVVRG 454          
BLAST of Dihydropyrimidinase vs. Ensembl Fly
Match: CG6106 (gene:FBgn0030914 transcript:FBtr0074553)

HSP 1 Score: 62.3882 bits (150), Expect = 7.147e-10
Identity = 52/237 (21.94%), Postives = 91/237 (38.40%), Query Frame = 1
Query:  778 LYSRPEEVECEATNRAIMLADQANCPLYVVHVMSKGAAD---IISDARRQGKVVFGEPIAAGLGTDGSHYSHSCWRHAAGYVMSPPLRNDRNTSKHLMQLLASGDLECTGTDHCVFKASQKAL----GKDDFRSIPNGVNGVEDRMSVIWEKGV---VTGILDPCKFVAVTSTNAAKIFNIYPKKGRIDIGSDADLVLWNPDVRRTISASTHYQNVDFNIFEGMHCHGVAEMVISGG 1458
            L +RP ++E  AT     LA++   P   +H+++  + +   ++ + RRQG  +  +     L                 +   PP+R  RN  +    L   G +   G+DH       +AL    G+ +F     G+N ++  +SV+W        +  L       +     A +  +   KGRI  G DAD  +W+P+   T+     Y       + G    GV    +  G
Sbjct:  224 LVTRPPQMEISATQLLCRLANRH--PRRCIHILNCSSGESLPLVEECRRQGGNLTVDTCPHYLALAAEDVPDC----GTEFKTWPPIRERRNQEQLWQALRPGGAIRMIGSDHSPATPGARALTCGRGRGNFLKAWPGINSLQLSLSVVWTAAANRRGSANLTIADIHRLMCQEPANLCGLSASKGRIAEGYDADFCVWSPEEEFTVGPELLYTATKATPYAGQKLRGVVHATVVRG 454          
BLAST of Dihydropyrimidinase vs. Ensembl Zebrafish
Match: dpysl2b (dihydropyrimidinase like 2b [Source:ZFIN;Acc:ZDB-GENE-031105-1])

HSP 1 Score: 639.802 bits (1649), Expect = 0.000e+0
Identity = 305/576 (52.95%), Postives = 409/576 (71.01%), Query Frame = 1
Query:  139 QSSQNRLCIKGAKIVNDDRMFDADVYIEDGIIKQLGTNLVIPGGVRCVEANGKLLIPGGIDTHTHMEFPFMGTVSSDDFYSGTRAALAGGTTMIIDFVIGQKGTSLIDSYNQYREKADSKVCCDYGLHVIVSSYNESVGNEMEKLASEHGINSFKIFMAYKDSLMLEDDEMYEVFKKCKSIGALAQVHAENGKLIEKKSLELISKGITGPEGHLYSRPEEVECEATNRAIMLADQANCPLYVVHVMSKGAADIISDARRQGKVVFGEPIAAGLGTDGSHYSHSCWRHAAGYVMSPPLRNDRNTSKHLMQLLASGDLECTGTDHCVFKASQKALGKDDFRSIPNGVNGVEDRMSVIWEKGVVTGILDPCKFVAVTSTNAAKIFNIYPKKGRIDIGSDADLVLWNPDVRRTISASTHYQNVDFNIFEGMHCHGVAEMVISGGKVVLEDGNLRVAQGTGKFVPTNPFCNYVFNKVKLRDQCHKTLANKVERQPYDGPVEDLSKEMTNLNMNFDDDTDSQQNAISSEFVNTKRPLTSGGGRHMQDSSFALSGAQIDDNLPTRSGIRTRQPPGGTA--TSL 1860
            + + +RL IKGAKIVNDD+ F AD+Y+EDG+IKQ+G NL++PGGV+ ++A+G++++PGGID HT  + P  G  ++DDFY GTRAALAGGTTMI+D V+ + GTSLI ++NQ+RE ADSK CCDY LHV ++ +++ V  EME L  +HG+NSF +++AYKD   L D ++YEVF   + +GA+AQVHAENG +I ++   ++  GITGPEGH+ SRPEEVE EA NR++ +A+Q NCPLY+  VMSK AAD+I+ AR++G VV+GEPI A +GTDGSHY    W  AA YV SPPL  D  T  +L  LL+ GDL+ TG+ HC F  SQ+A+GKDDF  IP G NG E+RMS+IW+K VVTG +D  +FVAVTSTNAAKIFN+YP+KGRI +GSDADLVLW+PDV + ISA +H   V++NIFEGM   GV  +VIS GK+VLE+G L   +G+G+F+   PF +YV+ ++K R +  +     V R  YDGPV ++S     +            +A +S      +P+     R++  S F+LSGAQ+DDN+P R+  R   PPGG A  TSL
Sbjct:    7 KRNSDRLLIKGAKIVNDDQSFCADIYMEDGLIKQIGENLIVPGGVKTIDAHGRMVMPGGIDVHTRFQMPDRGMTAADDFYQGTRAALAGGTTMIVDHVVPEPGTSLISAFNQWREWADSKACCDYSLHVDITEWHKGVQEEMEALVKDHGVNSFLVYLAYKDFFQLTDSQIYEVFSVIRDLGAIAQVHAENGDIIAEEQRRILDLGITGPEGHVLSRPEEVEAEAVNRSVTVANQTNCPLYITKVMSKSAADVIAQARKKGTVVYGEPITASIGTDGSHYWSKNWAKAAAYVTSPPLSPDPTTPDYLNSLLSCGDLQVTGSAHCTFNTSQRAVGKDDFTLIPEGTNGTEERMSIIWDKCVVTGKMDENQFVAVTSTNAAKIFNLYPRKGRIAVGSDADLVLWDPDVTKIISAKSHNLAVEYNIFEGMEVRGVPLVVISQGKIVLEEGTLHTTEGSGRFISRKPFPDYVYKRIKARSRLAELRG--VPRGLYDGPVCEVSVTPKAVT--------PASSAKTSPAKQPGQPV-----RNLHQSGFSLSGAQVDDNIPRRNTQRIVAPPGGRANITSL 567          
BLAST of Dihydropyrimidinase vs. Ensembl Zebrafish
Match: dpys (dihydropyrimidinase [Source:ZFIN;Acc:ZDB-GENE-070508-1])

HSP 1 Score: 637.106 bits (1642), Expect = 0.000e+0
Identity = 300/494 (60.73%), Postives = 375/494 (75.91%), Query Frame = 1
Query:  142 SSQNRLCIKGAKIVNDDRMFDADVYIEDGIIKQLGTNLVIPGGVRCVEANGKLLIPGGIDTHTHMEFPFMGTVSSDDFYSGTRAALAGGTTMIIDFVIGQKGTSLIDSYNQYREKADSKVCCDYGLHVIVSSYNESVGNEMEKLASEHGINSFKIFMAYKDSLMLEDDEMYEVFKKCKSIGALAQVHAENGKLIEKKSLELISKGITGPEGHLYSRPEEVECEATNRAIMLADQANCPLYVVHVMSKGAADIISDARRQGKVVFGEPIAAGLGTDGSHYSHSCWRHAAGYVMSPPLRNDRNTSKHLMQLLASGDLECTGTDHCVFKASQKALGKDDFRSIPNGVNGVEDRMSVIWEKGVVTGILDPCKFVAVTSTNAAKIFNIYPKKGRIDIGSDADLVLWNPDVRRTISASTHYQNVDFNIFEGMHCHGVAEMVISGGKVVLEDGNLRVAQGTGKFVPTNPFCNYVFNKVKLRDQCHKTLANKVERQPYDGPV 1623
            ++Q+ + IKG K+VN+D    ADVYIEDG+I  +GT+L +  G R ++A  KL++PGGID+HTHME  FMGT ++DDF +GT+AA+AGGTTMI+DFVI QKG SL+++Y ++R  AD KVCCDY LH+ V+ ++++V  EME L SE GINSFK+FMAYKD  ML+D E+Y VF  CK IGA+AQVHAENG LI + +  ++S GITGPEGH   RPEEVE EAT RAI +A   NCPLYVVHVMSK AA ++++ARR G++VFGEPIAAGLGTDG+HY H  W HAAG+VM PPLR D +T  +LM LLA+ DL  TGTD+C F   QKALGKDDF  IPNGVNGVEDRMSVIWEKGV +G +D  +FVAVTSTNAAKIFN+YP+KGRI  GSDADLV+W+P   R ISA TH+Q VD+NIFEGM CHGV  + IS GKVV E+G L    G G+++P  PF  +V+ ++  R++     A  V R+PY G +
Sbjct:    2 TAQSCILIKGGKVVNEDFSVMADVYIEDGVISGVGTDLQVAAGTRVIDATHKLVLPGGIDSHTHMELSFMGTTTADDFQTGTQAAVAGGTTMILDFVIAQKGCSLLEAYERWRRTADPKVCCDYSLHMAVTWWDDTVKKEMETLVSEKGINSFKMFMAYKDLYMLQDLELYAVFSTCKEIGAIAQVHAENGDLIAEGAKRMLSLGITGPEGHEMCRPEEVEAEATQRAITIAHATNCPLYVVHVMSKSAAKVVANARRNGRLVFGEPIAAGLGTDGTHYWHENWAHAAGFVMGPPLRPDPSTPGYLMDLLANDDLSVTGTDNCTFSVCQKALGKDDFTKIPNGVNGVEDRMSVIWEKGVHSGKMDENRFVAVTSTNAAKIFNLYPRKGRIAKGSDADLVIWDPKASRVISAKTHHQAVDYNIFEGMLCHGVPVVTISRGKVVYENGKLFTKPGEGRYIPRKPFAEFVYKRINQREKVGTPSA--VCREPYTGEI 493          
BLAST of Dihydropyrimidinase vs. Ensembl Zebrafish
Match: FO904844.1 (dihydropyrimidinase like 2a [Source:NCBI gene;Acc:798555])

HSP 1 Score: 634.795 bits (1636), Expect = 0.000e+0
Identity = 306/587 (52.13%), Postives = 412/587 (70.19%), Query Frame = 1
Query:  115 VKKVPLHLQSSQNRLCIKGAKIVNDDRMFDADVYIEDGIIKQLGTNLVIPGGVRCVEANGKLLIPGGIDTHTHMEFPFMGTVSSDDFYSGTRAALAGGTTMIIDFVIGQKGTSLIDSYNQYREKADSKVCCDYGLHVIVSSYNESVGNEMEKLASEHGINSFKIFMAYKDSLMLEDDEMYEVFKKCKSIGALAQVHAENGKLIEKKSLELISKGITGPEGHLYSRPEEVECEATNRAIMLADQANCPLYVVHVMSKGAADIISDARRQGKVVFGEPIAAGLGTDGSHYSHSCWRHAAGYVMSPPLRNDRNTSKHLMQLLASGDLECTGTDHCVFKASQKALGKDDFRSIPNGVNGVEDRMSVIWEKGVVTGILDPCKFVAVTSTNAAKIFNIYPKKGRIDIGSDADLVLWNPDVRRTISASTHYQNVDFNIFEGMHCHGVAEMVISGGKVVLEDGNLRVAQGTGKFVPTNPFCNYVFNKVKLRDQCHKTLANKVERQPYDGPVEDLS---KEMTNLNMNFDDDTDSQQNAISSEFVNTKRPLTSGGGRHMQDSSFALSGAQIDDNLPTRSGIRTRQPPGGTA--TSL 1860
            V++ PL      +RL IKGAKIVNDD+ F AD+Y+EDG+IKQ+G NL++PGGV+ +EA+G++LIPGGID HT  + P  G  ++DDFY GTRAALAGGTTMI+D V+ + G SLI ++NQ+RE AD K CCDY LHV ++ +++ +  E+E L  +HG+NSF +++AYKD   L D +MYEVF   + +GA+AQVHAENG +I ++   ++  GITGPEGH+ SRPEEVE EA NRA+ +A+Q NCPLY+  VMSK AAD+I+ AR++G VV+GEPI+A LGTDG+HY    W  AA ++ SPPL  D  T  +L  LLA GDL+ TG+ HC F  SQ+A+GKD+F  IP G NG E+RMS+IW+K VVTG +D  +FV VTSTNAAKIFN+YP+KGRI +GSDADLVLW+PD  + ISA +H+  V++NIFEGM   G   +VIS GKVVLE+GNL   +G+G+++   PF +YV+ ++K R +  +     V R  YDGPV +++   K MT +            +  +S      +P+     R++  S F+LSGAQ+DDN+P R+  R   PPGG A  TSL
Sbjct:   12 VQRYPL------DRLLIKGAKIVNDDQSFHADIYMEDGVIKQIGENLIVPGGVKIIEAHGRMLIPGGIDVHTRFQMPDRGMTAADDFYQGTRAALAGGTTMIMDHVVPEPGFSLISAFNQWREWADQKSCCDYSLHVDITEWHKGLQEEIEMLVKDHGVNSFLVYLAYKDIFQLNDSQMYEVFSVIRDLGAIAQVHAENGDIIAEEQKRILGLGITGPEGHVLSRPEEVEAEAVNRAVTIANQTNCPLYITKVMSKSAADVIAQARKKGTVVYGEPISASLGTDGTHYWSKNWAKAAAFITSPPLSPDPTTPDYLNSLLACGDLQVTGSAHCTFNTSQRAVGKDNFTFIPEGTNGTEERMSIIWDKCVVTGKMDENQFVLVTSTNAAKIFNLYPRKGRIAVGSDADLVLWDPDATKIISAKSHHLAVEYNIFEGMEVRGAPLVVISQGKVVLEEGNLHTTEGSGRYISRKPFPDYVYKRIKARSRLAEL--RGVPRGLYDGPVCEVTVTPKVMTPVT-----------SGKTSPVKPAPQPV-----RNLHQSGFSLSGAQVDDNVPRRTTQRIVAPPGGRANITSL 574          
BLAST of Dihydropyrimidinase vs. Ensembl Zebrafish
Match: dpysl3 (dihydropyrimidinase like 3 [Source:NCBI gene;Acc:553166])

HSP 1 Score: 616.305 bits (1588), Expect = 0.000e+0
Identity = 297/579 (51.30%), Postives = 394/579 (68.05%), Query Frame = 1
Query:  112 GVKKVPLHLQSSQNRLCIKGAKIVNDDRMFDADVYIEDGIIKQLGTNLVIPGGVRCVEANGKLLIPGGIDTHTHMEFPFMGTVSSDDFYSGTRAALAGGTTMIIDFVIGQKGTSLIDSYNQYREKADSKVCCDYGLHVIVSSYNESVGNEMEKLASEHGINSFKIFMAYKDSLMLEDDEMYEVFKKCKSIGALAQVHAENGKLIEKKSLELISKGITGPEGHLYSRPEEVECEATNRAIMLADQANCPLYVVHVMSKGAADIISDARRQGKVVFGEPIAAGLGTDGSHYSHSCWRHAAGYVMSPPLRNDRNTSKHLMQLLASGDLECTGTDHCVFKASQKALGKDDFRSIPNGVNGVEDRMSVIWEKGVVTGILDPCKFVAVTSTNAAKIFNIYPKKGRIDIGSDADLVLWNPDVRRTISASTHYQNVDFNIFEGMHCHGVAEMVISGGKVVLEDGNLRVAQGTGKFVPTNPFCNYVFNKVKLRDQCHKTLANKVERQPYDGPVEDLSKEMTNLNMNFDDDTDSQQNAISSEFVNTKRPLTSGGGRHMQDSSFALSGAQIDDNLPTR-SGIRTRQPPGG 1845
            G K +P   + +  RL IKG +IVNDD+ F AD+Y+EDG+IKQ+G NL++PGGV+ +EANGK++IPGGID HTH++ PF GT ++DDF  GT+AALAGGTTMI+D VI + G SL+++++++ + AD K CCDY LHV ++ +N+SV  E+E L  E G+NSF+++MA+KD   + + E+YEVF      G +AQVHAENG++I ++   ++  GITGPEGH+ SRPEE+E EA  RA+ +A Q NCPLYV  VMSK AADIIS AR++G VVFGEPI A LGTDG+HY    W  AA +V SPPL  D  T  +L  LLASGDL   G+ HC F  +QKA+GKDDF  IP GVNG E+RMS+IW+K VVTG +D   FVAVTSTNAAKI N+YP+KGRI +GSD+DLV+W+ D  RTI+A TH+   ++N+FEGM   G   +V+  GK+VLEDGNL    GTG+F+P +PF ++ + +VK R Q    +   V R  YDGPV +           F   +     + S+    TK P+     R++  S F LSG +     P R +G R   PPGG
Sbjct:    5 GKKNIP---KITSERLLIKGGRIVNDDQSFYADIYMEDGVIKQIGDNLIVPGGVKTIEANGKMVIPGGIDIHTHLQMPFRGTTTADDFTQGTKAALAGGTTMIVDHVIPEPGCSLLEAFDRWSKWADEKACCDYSLHVDITHWNDSVKQEVETLIKEKGVNSFQVYMAFKDLYQMSNTELYEVFTFLGEHGGIAQVHAENGEIIAEEQARMLEMGITGPEGHVLSRPEELEAEAVFRAVTIASQTNCPLYVTRVMSKSAADIISQARKKGNVVFGEPITASLGTDGTHYWSKNWAKAASFVTSPPLSPDPTTPDYLNTLLASGDLSVVGSAHCTFSVAQKAIGKDDFTQIPEGVNGAEERMSIIWDKAVVTGKMDENMFVAVTSTNAAKILNLYPRKGRIAVGSDSDLVIWDTDAVRTITAKTHHSAAEYNVFEGMELRGAPMLVVCQGKIVLEDGNLHATSGTGRFIPCSPFPDFAYKRVKARKQL--AILKAVPRGMYDGPVSE-----------FSPMSRGGTPSASTRTSPTKVPV-----RNLHQSGFTLSGPE---EAPIRPAGRRIVVPPGG 559          
BLAST of Dihydropyrimidinase vs. Ensembl Zebrafish
Match: dpysl4 (dihydropyrimidinase like 4 [Source:ZFIN;Acc:ZDB-GENE-050720-3])

HSP 1 Score: 608.216 bits (1567), Expect = 0.000e+0
Identity = 290/567 (51.15%), Postives = 393/567 (69.31%), Query Frame = 1
Query:  145 SQNRLCIKGAKIVNDDRMFDADVYIEDGIIKQLGTNLVIPGGVRCVEANGKLLIPGGIDTHTHMEFPFMGTVSSDDFYSGTRAALAGGTTMIIDFVIGQKGTSLIDSYNQYREKADSKVCCDYGLHVIVSSYNESVGNEMEKLASEHGINSFKIFMAYKDSLMLEDDEMYEVFKKCKSIGALAQVHAENGKLIEKKSLELISKGITGPEGHLYSRPEEVECEATNRAIMLADQANCPLYVVHVMSKGAADIISDARRQGKVVFGEPIAAGLGTDGSHYSHSCWRHAAGYVMSPPLRNDRNTSKHLMQLLASGDLECTGTDHCVFKASQKALGKDDFRSIPNGVNGVEDRMSVIWEKGVVTGILDPCKFVAVTSTNAAKIFNIYPKKGRIDIGSDADLVLWNPDVRRTISASTHYQNVDFNIFEGMHCHGVAEMVISGGKVVLEDGNLRVAQGTGKFVPTNPFCNYVFNKVKLRDQCHKTLANKVERQPYDGPVEDLSKEMTNLNMNFDDDTDSQQNAISSEFVNTKRPLTSGGGRHMQDSSFALSGAQIDDNLPTRSGIRTRQPPGG 1845
            + ++L IKG KIVNDD+ F AD+Y+EDGIIKQ+G NL++P GV+ V+A G ++IPGGID +T ++ P +G   +DDFY GTRAALAGGTTMIID V+ + G+SL+ +++Q+++ AD + CCDY LH+ ++ +++ +  E+E L  + G+NSF IFMAYKD     D ++YE+F   + +GA+AQVHAENG +IE++  +L+  GITGPEGH+ S PEEVE EA  RAI +A QANCPLY+  VMSK AAD+I+ AR++G V++GEPIAA LGTDGSHY    W  AA +VMSPPL  D +T  +L  LL+ GDL+ T + +C F  +QKA+GKDDF  IP G NG+E+RMS++W+K V TG +D   FVAVTSTNAAKIFN+YP+KGRI +GSDAD+V+WN    RT SA TH   V+ NIFEGM C G   +VIS G++VLEDG L V +G+G+F+P   + +YV+ ++K R +     A  V R  YDGPV D+      ++M             S      K PL  G  R++  S F LSG Q+DD++P R+  +   PPGG
Sbjct:   13 TSDKLIIKGGKIVNDDQSFYADIYVEDGIIKQIGENLIVPTGVKTVDAYGHIVIPGGIDVNTCLQAPHLGMSPADDFYHGTRAALAGGTTMIIDHVVPEPGSSLLSAFDQWKDTADKRSCCDYSLHIDITRWHDGLFEELESLVKDKGVNSFLIFMAYKDKFQSSDTQIYEMFSAMRELGAIAQVHAENGDIIEEEQKKLLDLGITGPEGHVLSHPEEVETEAVYRAITIAKQANCPLYITKVMSKPAADLIAKARKKGMVIYGEPIAASLGTDGSHYWSKNWAEAAAFVMSPPLNPDTSTPDYLNSLLSCGDLQVTASANCTFTTAQKAVGKDDFTFIPEGTNGIEERMSIVWDKAVATGKMDENDFVAVTSTNAAKIFNLYPRKGRIAVGSDADIVIWNTKETRTFSAKTHNLTVEVNIFEGMECRGFPVLVISQGRIVLEDGTLSVMEGSGRFIPRKAYPDYVYKRIKARSRMAD--ARGVPRGNYDGPVHDV------ISMTKSVPATPTTRGPSCP---GKTPL--GPTRNLHQSGFTLSGTQMDDHIPRRTAQKIVAPPGG 566          
BLAST of Dihydropyrimidinase vs. Ensembl Xenopus
Match: bco2 (beta-carotene oxygenase 2 [Source:Xenbase;Acc:XB-GENE-5747659])

HSP 1 Score: 640.958 bits (1652), Expect = 0.000e+0
Identity = 306/585 (52.31%), Postives = 415/585 (70.94%), Query Frame = 1
Query:  112 GVKKVPLHLQSSQNRLCIKGAKIVNDDRMFDADVYIEDGIIKQLGTNLVIPGGVRCVEANGKLLIPGGIDTHTHMEFPFMGTVSSDDFYSGTRAALAGGTTMIIDFVIGQKGTSLIDSYNQYREKADSKVCCDYGLHVIVSSYNESVGNEMEKLASEHGINSFKIFMAYKDSLMLEDDEMYEVFKKCKSIGALAQVHAENGKLIEKKSLELISKGITGPEGHLYSRPEEVECEATNRAIMLADQANCPLYVVHVMSKGAADIISDARRQGKVVFGEPIAAGLGTDGSHYSHSCWRHAAGYVMSPPLRNDRNTSKHLMQLLASGDLECTGTDHCVFKASQKALGKDDFRSIPNGVNGVEDRMSVIWEKGVVTGILDPCKFVAVTSTNAAKIFNIYPKKGRIDIGSDADLVLWNPDVRRTISASTHYQNVDFNIFEGMHCHGVAEMVISGGKVVLEDGNLRVAQGTGKFVPTNPFCNYVFNKVKLRDQCHKTLANKVERQPYDGPVEDLSKEMTNLNMNFDDDTDSQQNAISSEFVNTKRPLTSGGGRHMQDSSFALSGAQIDDNLPTRSGIRTRQPPGGTA--TSL 1860
            G K +P   + + +RL IKG KIVNDD+ F AD+Y+EDG+IKQ+G NL++PGGV+ +EA+G+++IPGGID HT  + P  G VSSDDF+ GT+AALAGGTTMIID V+ + G+SL+ +++Q+RE AD+K CCDY LHV ++ +++ V  EME L  +HG+NSF ++MAYKD   L D ++YEVF   + IGA+A+VHAENG +I ++ L ++ +GI GPEGH+ SRPEEVE EA NR+I +A+Q NCPLYV  VMSK +A++I+ AR++G VV+GEPI A LGTDGSHY    W  AA +V SPPL  D +T   L  LL+ GDL+  G+ HC F  +QKA+GKD+F  IP G NG E+RMSV+W++ VV+G +D  +FVAVTSTNAAKIFN+YP+KGRI +GSDADLV+W+PD  RTISA TH  NV++NIFEGM C G   +VIS GK+VLE+G L   +G+G+++P  PF +YV+ ++K R +  +     V R  YDGPV ++S     +            +A +S      +P+     R++  S F+LSGAQ+DDN+P R+  R   PPGG A  TSL
Sbjct:    6 GKKNIP---RITSDRLLIKGGKIVNDDQSFHADIYMEDGLIKQIGENLIVPGGVKTIEAHGRMVIPGGIDVHTCFQKPCNGMVSSDDFFQGTKAALAGGTTMIIDHVVPEPGSSLLSAFDQWREWADTKSCCDYSLHVDITEWHKGVQEEMEALVKDHGVNSFLVYMAYKDQYQLTDSQIYEVFSVIRDIGAIAEVHAENGDVIAEEQLRILEQGINGPEGHVLSRPEEVEAEAANRSITIANQTNCPLYVTKVMSKSSAEVIAQARKKGAVVYGEPITASLGTDGSHYWSKNWAKAAAFVTSPPLSPDPSTPDFLNSLLSCGDLQVCGSSHCTFNTAQKAVGKDNFTLIPEGTNGAEERMSVVWDRAVVSGKMDENQFVAVTSTNAAKIFNLYPRKGRIAVGSDADLVIWDPDSVRTISAKTHNSNVEYNIFEGMECRGSPLVVISQGKIVLEEGTLHATEGSGRYIPRKPFPDYVYKRIKARSRLAELRG--VPRGLYDGPVCEVSVTPKAVT--------PASSAKTSPAKQPAQPI-----RNLHQSGFSLSGAQVDDNIPRRTTQRIVAPPGGRANITSL 572          
BLAST of Dihydropyrimidinase vs. Ensembl Xenopus
Match: bco2 (beta-carotene oxygenase 2 [Source:Xenbase;Acc:XB-GENE-5747659])

HSP 1 Score: 640.573 bits (1651), Expect = 0.000e+0
Identity = 304/578 (52.60%), Postives = 411/578 (71.11%), Query Frame = 1
Query:  133 HLQSSQNRLCIKGAKIVNDDRMFDADVYIEDGIIKQLGTNLVIPGGVRCVEANGKLLIPGGIDTHTHMEFPFMGTVSSDDFYSGTRAALAGGTTMIIDFVIGQKGTSLIDSYNQYREKADSKVCCDYGLHVIVSSYNESVGNEMEKLASEHGINSFKIFMAYKDSLMLEDDEMYEVFKKCKSIGALAQVHAENGKLIEKKSLELISKGITGPEGHLYSRPEEVECEATNRAIMLADQANCPLYVVHVMSKGAADIISDARRQGKVVFGEPIAAGLGTDGSHYSHSCWRHAAGYVMSPPLRNDRNTSKHLMQLLASGDLECTGTDHCVFKASQKALGKDDFRSIPNGVNGVEDRMSVIWEKGVVTGILDPCKFVAVTSTNAAKIFNIYPKKGRIDIGSDADLVLWNPDVRRTISASTHYQNVDFNIFEGMHCHGVAEMVISGGKVVLEDGNLRVAQGTGKFVPTNPFCNYVFNKVKLRDQCHKTLANKVERQPYDGPVEDLSKEMTNLNMNFDDDTDSQQNAISSEFVNTKRPLTSGGGRHMQDSSFALSGAQIDDNLPTRSGIRTRQPPGGTA--TSL 1860
            +L    +RL IKG KIVNDD+ F AD+Y+EDG+IKQ+G NL++PGGV+ +EA+G+++IPGGID HT  + P  G VSSDDF+ GT+AALAGGTTMIID V+ + G+SL+ +++Q+RE AD+K CCDY LHV ++ +++ V  EME L  +HG+NSF ++MAYKD   L D ++YEVF   + IGA+A+VHAENG +I ++ L ++ +GI GPEGH+ SRPEEVE EA NR+I +A+Q NCPLYV  VMSK +A++I+ AR++G VV+GEPI A LGTDGSHY    W  AA +V SPPL  D +T   L  LL+ GDL+  G+ HC F  +QKA+GKD+F  IP G NG E+RMSV+W++ VV+G +D  +FVAVTSTNAAKIFN+YP+KGRI +GSDADLV+W+PD  RTISA TH  NV++NIFEGM C G   +VIS GK+VLE+G L   +G+G+++P  PF +YV+ ++K R +  +     V R  YDGPV ++S     +            +A +S      +P+     R++  S F+LSGAQ+DDN+P R+  R   PPGG A  TSL
Sbjct:  135 NLNDKSDRLLIKGGKIVNDDQSFHADIYMEDGLIKQIGENLIVPGGVKTIEAHGRMVIPGGIDVHTCFQKPCNGMVSSDDFFQGTKAALAGGTTMIIDHVVPEPGSSLLSAFDQWREWADTKSCCDYSLHVDITEWHKGVQEEMEALVKDHGVNSFLVYMAYKDQYQLTDSQIYEVFSVIRDIGAIAEVHAENGDVIAEEQLRILEQGINGPEGHVLSRPEEVEAEAANRSITIANQTNCPLYVTKVMSKSSAEVIAQARKKGAVVYGEPITASLGTDGSHYWSKNWAKAAAFVTSPPLSPDPSTPDFLNSLLSCGDLQVCGSSHCTFNTAQKAVGKDNFTLIPEGTNGAEERMSVVWDRAVVSGKMDENQFVAVTSTNAAKIFNLYPRKGRIAVGSDADLVIWDPDSVRTISAKTHNSNVEYNIFEGMECRGSPLVVISQGKIVLEEGTLHATEGSGRYIPRKPFPDYVYKRIKARSRLAELRG--VPRGLYDGPVCEVSVTPKAVT--------PASSAKTSPAKQPAQPI-----RNLHQSGFSLSGAQVDDNIPRRTTQRIVAPPGGRANITSL 697          
BLAST of Dihydropyrimidinase vs. Ensembl Xenopus
Match: bco2 (beta-carotene oxygenase 2 [Source:Xenbase;Acc:XB-GENE-5747659])

HSP 1 Score: 639.417 bits (1648), Expect = 0.000e+0
Identity = 304/578 (52.60%), Postives = 411/578 (71.11%), Query Frame = 1
Query:  133 HLQSSQNRLCIKGAKIVNDDRMFDADVYIEDGIIKQLGTNLVIPGGVRCVEANGKLLIPGGIDTHTHMEFPFMGTVSSDDFYSGTRAALAGGTTMIIDFVIGQKGTSLIDSYNQYREKADSKVCCDYGLHVIVSSYNESVGNEMEKLASEHGINSFKIFMAYKDSLMLEDDEMYEVFKKCKSIGALAQVHAENGKLIEKKSLELISKGITGPEGHLYSRPEEVECEATNRAIMLADQANCPLYVVHVMSKGAADIISDARRQGKVVFGEPIAAGLGTDGSHYSHSCWRHAAGYVMSPPLRNDRNTSKHLMQLLASGDLECTGTDHCVFKASQKALGKDDFRSIPNGVNGVEDRMSVIWEKGVVTGILDPCKFVAVTSTNAAKIFNIYPKKGRIDIGSDADLVLWNPDVRRTISASTHYQNVDFNIFEGMHCHGVAEMVISGGKVVLEDGNLRVAQGTGKFVPTNPFCNYVFNKVKLRDQCHKTLANKVERQPYDGPVEDLSKEMTNLNMNFDDDTDSQQNAISSEFVNTKRPLTSGGGRHMQDSSFALSGAQIDDNLPTRSGIRTRQPPGGTA--TSL 1860
            +L    +RL IKG KIVNDD+ F AD+Y+EDG+IKQ+G NL++PGGV+ +EA+G+++IPGGID HT  + P  G VSSDDF+ GT+AALAGGTTMIID V+ + G+SL+ +++Q+RE AD+K CCDY LHV ++ +++ V  EME L  +HG+NSF ++MAYKD   L D ++YEVF   + IGA+A+VHAENG +I ++ L ++ +GI GPEGH+ SRPEEVE EA NR+I +A+Q NCPLYV  VMSK +A++I+ AR++G VV+GEPI A LGTDGSHY    W  AA +V SPPL  D +T   L  LL+ GDL+  G+ HC F  +QKA+GKD+F  IP G NG E+RMSV+W++ VV+G +D  +FVAVTSTNAAKIFN+YP+KGRI +GSDADLV+W+PD  RTISA TH  NV++NIFEGM C G   +VIS GK+VLE+G L   +G+G+++P  PF +YV+ ++K R +  +     V R  YDGPV ++S     +            +A +S      +P+     R++  S F+LSGAQ+DDN+P R+  R   PPGG A  TSL
Sbjct:  127 NLNDKSDRLLIKGGKIVNDDQSFHADIYMEDGLIKQIGENLIVPGGVKTIEAHGRMVIPGGIDVHTCFQKPCNGMVSSDDFFQGTKAALAGGTTMIIDHVVPEPGSSLLSAFDQWREWADTKSCCDYSLHVDITEWHKGVQEEMEALVKDHGVNSFLVYMAYKDQYQLTDSQIYEVFSVIRDIGAIAEVHAENGDVIAEEQLRILEQGINGPEGHVLSRPEEVEAEAANRSITIANQTNCPLYVTKVMSKSSAEVIAQARKKGAVVYGEPITASLGTDGSHYWSKNWAKAAAFVTSPPLSPDPSTPDFLNSLLSCGDLQVCGSSHCTFNTAQKAVGKDNFTLIPEGTNGAEERMSVVWDRAVVSGKMDENQFVAVTSTNAAKIFNLYPRKGRIAVGSDADLVIWDPDSVRTISAKTHNSNVEYNIFEGMECRGSPLVVISQGKIVLEEGTLHATEGSGRYIPRKPFPDYVYKRIKARSRLAELRG--VPRGLYDGPVCEVSVTPKAVT--------PASSAKTSPAKQPAQPI-----RNLHQSGFSLSGAQVDDNIPRRTTQRIVAPPGGRANITSL 689          
BLAST of Dihydropyrimidinase vs. Ensembl Xenopus
Match: bco2 (beta-carotene oxygenase 2 [Source:Xenbase;Acc:XB-GENE-5747659])

HSP 1 Score: 638.647 bits (1646), Expect = 0.000e+0
Identity = 303/572 (52.97%), Postives = 409/572 (71.50%), Query Frame = 1
Query:  151 NRLCIKGAKIVNDDRMFDADVYIEDGIIKQLGTNLVIPGGVRCVEANGKLLIPGGIDTHTHMEFPFMGTVSSDDFYSGTRAALAGGTTMIIDFVIGQKGTSLIDSYNQYREKADSKVCCDYGLHVIVSSYNESVGNEMEKLASEHGINSFKIFMAYKDSLMLEDDEMYEVFKKCKSIGALAQVHAENGKLIEKKSLELISKGITGPEGHLYSRPEEVECEATNRAIMLADQANCPLYVVHVMSKGAADIISDARRQGKVVFGEPIAAGLGTDGSHYSHSCWRHAAGYVMSPPLRNDRNTSKHLMQLLASGDLECTGTDHCVFKASQKALGKDDFRSIPNGVNGVEDRMSVIWEKGVVTGILDPCKFVAVTSTNAAKIFNIYPKKGRIDIGSDADLVLWNPDVRRTISASTHYQNVDFNIFEGMHCHGVAEMVISGGKVVLEDGNLRVAQGTGKFVPTNPFCNYVFNKVKLRDQCHKTLANKVERQPYDGPVEDLSKEMTNLNMNFDDDTDSQQNAISSEFVNTKRPLTSGGGRHMQDSSFALSGAQIDDNLPTRSGIRTRQPPGGTA--TSL 1860
            +RL IKG KIVNDD+ F AD+Y+EDG+IKQ+G NL++PGGV+ +EA+G+++IPGGID HT  + P  G VSSDDF+ GT+AALAGGTTMIID V+ + G+SL+ +++Q+RE AD+K CCDY LHV ++ +++ V  EME L  +HG+NSF ++MAYKD   L D ++YEVF   + IGA+A+VHAENG +I ++ L ++ +GI GPEGH+ SRPEEVE EA NR+I +A+Q NCPLYV  VMSK +A++I+ AR++G VV+GEPI A LGTDGSHY    W  AA +V SPPL  D +T   L  LL+ GDL+  G+ HC F  +QKA+GKD+F  IP G NG E+RMSV+W++ VV+G +D  +FVAVTSTNAAKIFN+YP+KGRI +GSDADLV+W+PD  RTISA TH  NV++NIFEGM C G   +VIS GK+VLE+G L   +G+G+++P  PF +YV+ ++K R +  +     V R  YDGPV ++S     +            +A +S      +P+     R++  S F+LSGAQ+DDN+P R+  R   PPGG A  TSL
Sbjct:   46 DRLLIKGGKIVNDDQSFHADIYMEDGLIKQIGENLIVPGGVKTIEAHGRMVIPGGIDVHTCFQKPCNGMVSSDDFFQGTKAALAGGTTMIIDHVVPEPGSSLLSAFDQWREWADTKSCCDYSLHVDITEWHKGVQEEMEALVKDHGVNSFLVYMAYKDQYQLTDSQIYEVFSVIRDIGAIAEVHAENGDVIAEEQLRILEQGINGPEGHVLSRPEEVEAEAANRSITIANQTNCPLYVTKVMSKSSAEVIAQARKKGAVVYGEPITASLGTDGSHYWSKNWAKAAAFVTSPPLSPDPSTPDFLNSLLSCGDLQVCGSSHCTFNTAQKAVGKDNFTLIPEGTNGAEERMSVVWDRAVVSGKMDENQFVAVTSTNAAKIFNLYPRKGRIAVGSDADLVIWDPDSVRTISAKTHNSNVEYNIFEGMECRGSPLVVISQGKIVLEEGTLHATEGSGRYIPRKPFPDYVYKRIKARSRLAEL--RGVPRGLYDGPVCEVSVTPKAVT--------PASSAKTSPAKQPAQPI-----RNLHQSGFSLSGAQVDDNIPRRTTQRIVAPPGGRANITSL 602          
BLAST of Dihydropyrimidinase vs. Ensembl Xenopus
Match: bco2 (beta-carotene oxygenase 2 [Source:Xenbase;Acc:XB-GENE-5747659])

HSP 1 Score: 638.262 bits (1645), Expect = 0.000e+0
Identity = 303/572 (52.97%), Postives = 409/572 (71.50%), Query Frame = 1
Query:  151 NRLCIKGAKIVNDDRMFDADVYIEDGIIKQLGTNLVIPGGVRCVEANGKLLIPGGIDTHTHMEFPFMGTVSSDDFYSGTRAALAGGTTMIIDFVIGQKGTSLIDSYNQYREKADSKVCCDYGLHVIVSSYNESVGNEMEKLASEHGINSFKIFMAYKDSLMLEDDEMYEVFKKCKSIGALAQVHAENGKLIEKKSLELISKGITGPEGHLYSRPEEVECEATNRAIMLADQANCPLYVVHVMSKGAADIISDARRQGKVVFGEPIAAGLGTDGSHYSHSCWRHAAGYVMSPPLRNDRNTSKHLMQLLASGDLECTGTDHCVFKASQKALGKDDFRSIPNGVNGVEDRMSVIWEKGVVTGILDPCKFVAVTSTNAAKIFNIYPKKGRIDIGSDADLVLWNPDVRRTISASTHYQNVDFNIFEGMHCHGVAEMVISGGKVVLEDGNLRVAQGTGKFVPTNPFCNYVFNKVKLRDQCHKTLANKVERQPYDGPVEDLSKEMTNLNMNFDDDTDSQQNAISSEFVNTKRPLTSGGGRHMQDSSFALSGAQIDDNLPTRSGIRTRQPPGGTA--TSL 1860
            +RL IKG KIVNDD+ F AD+Y+EDG+IKQ+G NL++PGGV+ +EA+G+++IPGGID HT  + P  G VSSDDF+ GT+AALAGGTTMIID V+ + G+SL+ +++Q+RE AD+K CCDY LHV ++ +++ V  EME L  +HG+NSF ++MAYKD   L D ++YEVF   + IGA+A+VHAENG +I ++ L ++ +GI GPEGH+ SRPEEVE EA NR+I +A+Q NCPLYV  VMSK +A++I+ AR++G VV+GEPI A LGTDGSHY    W  AA +V SPPL  D +T   L  LL+ GDL+  G+ HC F  +QKA+GKD+F  IP G NG E+RMSV+W++ VV+G +D  +FVAVTSTNAAKIFN+YP+KGRI +GSDADLV+W+PD  RTISA TH  NV++NIFEGM C G   +VIS GK+VLE+G L   +G+G+++P  PF +YV+ ++K R +  +     V R  YDGPV ++S     +            +A +S      +P+     R++  S F+LSGAQ+DDN+P R+  R   PPGG A  TSL
Sbjct:   44 DRLLIKGGKIVNDDQSFHADIYMEDGLIKQIGENLIVPGGVKTIEAHGRMVIPGGIDVHTCFQKPCNGMVSSDDFFQGTKAALAGGTTMIIDHVVPEPGSSLLSAFDQWREWADTKSCCDYSLHVDITEWHKGVQEEMEALVKDHGVNSFLVYMAYKDQYQLTDSQIYEVFSVIRDIGAIAEVHAENGDVIAEEQLRILEQGINGPEGHVLSRPEEVEAEAANRSITIANQTNCPLYVTKVMSKSSAEVIAQARKKGAVVYGEPITASLGTDGSHYWSKNWAKAAAFVTSPPLSPDPSTPDFLNSLLSCGDLQVCGSSHCTFNTAQKAVGKDNFTLIPEGTNGAEERMSVVWDRAVVSGKMDENQFVAVTSTNAAKIFNLYPRKGRIAVGSDADLVIWDPDSVRTISAKTHNSNVEYNIFEGMECRGSPLVVISQGKIVLEEGTLHATEGSGRYIPRKPFPDYVYKRIKARSRLAELRG--VPRGLYDGPVCEVSVTPKAVT--------PASSAKTSPAKQPAQPI-----RNLHQSGFSLSGAQVDDNIPRRTTQRIVAPPGGRANITSL 600          
BLAST of Dihydropyrimidinase vs. Ensembl Mouse
Match: Dpysl2 (dihydropyrimidinase-like 2 [Source:MGI Symbol;Acc:MGI:1349763])

HSP 1 Score: 639.417 bits (1648), Expect = 0.000e+0
Identity = 306/585 (52.31%), Postives = 410/585 (70.09%), Query Frame = 1
Query:  112 GVKKVPLHLQSSQNRLCIKGAKIVNDDRMFDADVYIEDGIIKQLGTNLVIPGGVRCVEANGKLLIPGGIDTHTHMEFPFMGTVSSDDFYSGTRAALAGGTTMIIDFVIGQKGTSLIDSYNQYREKADSKVCCDYGLHVIVSSYNESVGNEMEKLASEHGINSFKIFMAYKDSLMLEDDEMYEVFKKCKSIGALAQVHAENGKLIEKKSLELISKGITGPEGHLYSRPEEVECEATNRAIMLADQANCPLYVVHVMSKGAADIISDARRQGKVVFGEPIAAGLGTDGSHYSHSCWRHAAGYVMSPPLRNDRNTSKHLMQLLASGDLECTGTDHCVFKASQKALGKDDFRSIPNGVNGVEDRMSVIWEKGVVTGILDPCKFVAVTSTNAAKIFNIYPKKGRIDIGSDADLVLWNPDVRRTISASTHYQNVDFNIFEGMHCHGVAEMVISGGKVVLEDGNLRVAQGTGKFVPTNPFCNYVFNKVKLRDQCHKTLANKVERQPYDGPVEDLSKEMTNLNMNFDDDTDSQQNAISSEFVNTKRPLTSGGGRHMQDSSFALSGAQIDDNLPTRSGIRTRQPPGGTA--TSL 1860
            G K +P   + + +RL IKG KIVNDD+ F AD+Y+EDG+IKQ+G NL++PGGV+ +EA+ +++IPGGID HT  + P  G  S+DDF+ GT+AALAGGTTMIID V+ + GTSL+ +++Q+RE ADSK CCDY LHV ++ +++ +  EME L  +HG+NSF ++MA+KD   L D ++YEV    + IGA+AQVHAENG +I ++   ++  GITGPEGH+ SRPEEVE EA NR+I +A+Q NCPLYV  VMSK AA++I+ AR++G VV+GEPI A LGTDGSHY    W  AA +V SPPL  D  T   L  LL+ GDL+ TG+ HC F  +QKA+GKD+F  IP G NG E+RMSVIW+K VVTG +D  +FVAVTSTNAAK+FN+YP+KGRI +GSDADLV+W+PD  +TISA TH   +++NIFEGM C G   +VIS GK+VLEDG L V +G+G+++P  PF ++V+ ++K R +  +     V R  YDGPV ++S     +            +A +S       P+     R++  S F+LSGAQIDDN+P R+  R   PPGG A  TSL
Sbjct:    5 GKKNIP---RITSDRLLIKGGKIVNDDQSFYADIYMEDGLIKQIGENLIVPGGVKTIEAHSRMVIPGGIDVHTRFQMPDQGMTSADDFFQGTKAALAGGTTMIIDHVVPEPGTSLLAAFDQWREWADSKSCCDYSLHVDITEWHKGIQEEMEALVKDHGVNSFLVYMAFKDRFQLTDSQIYEVLSVIRDIGAIAQVHAENGDIIAEEQQRILDLGITGPEGHVLSRPEEVEAEAVNRSITIANQTNCPLYVTKVMSKSAAEVIAQARKKGTVVYGEPITASLGTDGSHYWSKNWAKAAAFVTSPPLSPDPTTPDFLNSLLSCGDLQVTGSAHCTFNTAQKAVGKDNFTLIPEGTNGTEERMSVIWDKAVVTGKMDENQFVAVTSTNAAKVFNLYPRKGRISVGSDADLVIWDPDSVKTISAKTHNSALEYNIFEGMECRGSPLVVISQGKIVLEDGTLHVTEGSGRYIPRKPFPDFVYKRIKARSRLAEL--RGVPRGLYDGPVCEVSVTPKTVT--------PASSAKTSPAKQQAPPV-----RNLHQSGFSLSGAQIDDNIPRRTTQRIVAPPGGRANITSL 571          
BLAST of Dihydropyrimidinase vs. Ensembl Mouse
Match: Dpys (dihydropyrimidinase [Source:MGI Symbol;Acc:MGI:1928679])

HSP 1 Score: 628.246 bits (1619), Expect = 0.000e+0
Identity = 304/516 (58.91%), Postives = 377/516 (73.06%), Query Frame = 1
Query:  142 SSQNRLCIKGAKIVNDDRMFDADVYIEDGIIKQLGTNLVIP----GGVRCVEANGKLLIPGGIDTHTHMEFPFMGTVSSDDFYSGTRAALAGGTTMIIDFVIGQKGTSLIDSYNQYREKADSKVCCDYGLHVIVSSYNESVGNEMEKLASEHGINSFKIFMAYKDSLMLEDDEMYEVFKKCKSIGALAQVHAENGKLIEKKSLELISKGITGPEGHLYSRPEEVECEATNRAIMLADQANCPLYVVHVMSKGAADIISDARRQGKVVFGEPIAAGLGTDGSHYSHSCWRHAAGYVMSPPLRNDRNTSKHLMQLLASGDLECTGTDHCVFKASQKALGKDDFRSIPNGVNGVEDRMSVIWEKGVVTGILDPCKFVAVTSTNAAKIFNIYPKKGRIDIGSDADLVLWNPDVRRTISASTHYQNVDFNIFEGMHCHGVAEMVISGGKVVLEDGNLRVAQGTGKFVPTNPFCNYVFNKVKLRDQCHKTLANKVERQPYDGPVEDLSKEMTNLNMNFDDDT 1677
            + Q RL I+G +IVNDD    ADV +EDG+++ LG +L+ P     G+R ++A GKL++PGGIDTHTHM+FPFMG+ S DDFY GT+AALAGGTTMIIDF I QKG+SLI+++  +R  AD KVCCDY LHV V+ +++ V  EM+ LA + G+NSFK+FMAYK   M++D+++Y  F +CK IGA+AQVHAENG LI + + ++++ GITGPEGH   RPE VE EAT RAI +A   NCPLYVVHVMSK AA +++DARR G VV+GEPIAAGLGTDG  Y    W HAA +VM PPLR D  T   LM LLA+GDL  TG+D+C F   QKALGKDDF  IPNGVNGVEDRMSVIWEKGV +G +D  +FVAVTSTNAAKIFN+YPKKGRI +GSDAD+V+W+P+  R ISA TH+Q V+FNIFEGM CHGV  + IS G+VV E G   V  G GKF+P  PF  Y++ ++K RDQ    +   V+R PY G V  L    T      +DDT
Sbjct:    2 APQGRLLIRGGRIVNDDFSQVADVLVEDGVVRALGRDLLPPEDASRGLRILDAAGKLVLPGGIDTHTHMQFPFMGSQSVDDFYQGTKAALAGGTTMIIDFAIPQKGSSLIEAFETWRNWADPKVCCDYSLHVAVTWWSDKVKEEMKTLARDKGVNSFKMFMAYKGLYMVQDEQLYAAFSQCKEIGAIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIASAVNCPLYVVHVMSKSAAKVVADARRAGNVVYGEPIAAGLGTDGRQYWSEEWSHAAHHVMGPPLRPDPLTPGFLMDLLANGDLTTTGSDNCTFNTCQKALGKDDFTKIPNGVNGVEDRMSVIWEKGVHSGKMDENRFVAVTSTNAAKIFNLYPKKGRIAVGSDADIVIWDPEATRRISAKTHHQAVNFNIFEGMVCHGVPLVTISRGRVVYEAGVFNVTAGHGKFIPRQPFAEYIYKRIKQRDQTCTPV--PVKRAPYKGEVTTLKARETK-----EDDT 510          
BLAST of Dihydropyrimidinase vs. Ensembl Mouse
Match: Dpys (dihydropyrimidinase [Source:MGI Symbol;Acc:MGI:1928679])

HSP 1 Score: 628.246 bits (1619), Expect = 0.000e+0
Identity = 304/516 (58.91%), Postives = 377/516 (73.06%), Query Frame = 1
Query:  142 SSQNRLCIKGAKIVNDDRMFDADVYIEDGIIKQLGTNLVIP----GGVRCVEANGKLLIPGGIDTHTHMEFPFMGTVSSDDFYSGTRAALAGGTTMIIDFVIGQKGTSLIDSYNQYREKADSKVCCDYGLHVIVSSYNESVGNEMEKLASEHGINSFKIFMAYKDSLMLEDDEMYEVFKKCKSIGALAQVHAENGKLIEKKSLELISKGITGPEGHLYSRPEEVECEATNRAIMLADQANCPLYVVHVMSKGAADIISDARRQGKVVFGEPIAAGLGTDGSHYSHSCWRHAAGYVMSPPLRNDRNTSKHLMQLLASGDLECTGTDHCVFKASQKALGKDDFRSIPNGVNGVEDRMSVIWEKGVVTGILDPCKFVAVTSTNAAKIFNIYPKKGRIDIGSDADLVLWNPDVRRTISASTHYQNVDFNIFEGMHCHGVAEMVISGGKVVLEDGNLRVAQGTGKFVPTNPFCNYVFNKVKLRDQCHKTLANKVERQPYDGPVEDLSKEMTNLNMNFDDDT 1677
            + Q RL I+G +IVNDD    ADV +EDG+++ LG +L+ P     G+R ++A GKL++PGGIDTHTHM+FPFMG+ S DDFY GT+AALAGGTTMIIDF I QKG+SLI+++  +R  AD KVCCDY LHV V+ +++ V  EM+ LA + G+NSFK+FMAYK   M++D+++Y  F +CK IGA+AQVHAENG LI + + ++++ GITGPEGH   RPE VE EAT RAI +A   NCPLYVVHVMSK AA +++DARR G VV+GEPIAAGLGTDG  Y    W HAA +VM PPLR D  T   LM LLA+GDL  TG+D+C F   QKALGKDDF  IPNGVNGVEDRMSVIWEKGV +G +D  +FVAVTSTNAAKIFN+YPKKGRI +GSDAD+V+W+P+  R ISA TH+Q V+FNIFEGM CHGV  + IS G+VV E G   V  G GKF+P  PF  Y++ ++K RDQ    +   V+R PY G V  L    T      +DDT
Sbjct:    2 APQGRLLIRGGRIVNDDFSQVADVLVEDGVVRALGRDLLPPEDASRGLRILDAAGKLVLPGGIDTHTHMQFPFMGSQSVDDFYQGTKAALAGGTTMIIDFAIPQKGSSLIEAFETWRNWADPKVCCDYSLHVAVTWWSDKVKEEMKTLARDKGVNSFKMFMAYKGLYMVQDEQLYAAFSQCKEIGAIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIASAVNCPLYVVHVMSKSAAKVVADARRAGNVVYGEPIAAGLGTDGRQYWSEEWSHAAHHVMGPPLRPDPLTPGFLMDLLANGDLTTTGSDNCTFNTCQKALGKDDFTKIPNGVNGVEDRMSVIWEKGVHSGKMDENRFVAVTSTNAAKIFNLYPKKGRIAVGSDADIVIWDPEATRRISAKTHHQAVNFNIFEGMVCHGVPLVTISRGRVVYEAGVFNVTAGHGKFIPRQPFAEYIYKRIKQRDQTCTPV--PVKRAPYKGEVTTLKARETK-----EDDT 510          
BLAST of Dihydropyrimidinase vs. Ensembl Mouse
Match: Dpysl4 (dihydropyrimidinase-like 4 [Source:MGI Symbol;Acc:MGI:1349764])

HSP 1 Score: 623.239 bits (1606), Expect = 0.000e+0
Identity = 295/578 (51.04%), Postives = 404/578 (69.90%), Query Frame = 1
Query:  112 GVKKVPLHLQSSQNRLCIKGAKIVNDDRMFDADVYIEDGIIKQLGTNLVIPGGVRCVEANGKLLIPGGIDTHTHMEFPFMGTVSSDDFYSGTRAALAGGTTMIIDFVIGQKGTSLIDSYNQYREKADSKVCCDYGLHVIVSSYNESVGNEMEKLASEHGINSFKIFMAYKDSLMLEDDEMYEVFKKCKSIGALAQVHAENGKLIEKKSLELISKGITGPEGHLYSRPEEVECEATNRAIMLADQANCPLYVVHVMSKGAADIISDARRQGKVVFGEPIAAGLGTDGSHYSHSCWRHAAGYVMSPPLRNDRNTSKHLMQLLASGDLECTGTDHCVFKASQKALGKDDFRSIPNGVNGVEDRMSVIWEKGVVTGILDPCKFVAVTSTNAAKIFNIYPKKGRIDIGSDADLVLWNPDVRRTISASTHYQNVDFNIFEGMHCHGVAEMVISGGKVVLEDGNLRVAQGTGKFVPTNPFCNYVFNKVKLRDQCHKTLANKVERQPYDGPVEDLSKEMTNLNMNFDDDTDSQQNAISSEFVNTKRPLTSGGGRHMQDSSFALSGAQIDDNLPTRSGIRTRQPPGG 1845
            G K +P   + + +RL IKG KIVNDD+ F AD+Y+EDG+IKQ+G NL++PGG++ ++A+G +++PGG+D HT ++ P MG   +DDF  GT+AALAGGTTMI+D V    G SL+ +Y Q+RE+ADS  CCDY LHV +  ++ES   E+E L  + G+NSF +FMAYKD     D ++YE+F   + +GA+AQVHAENG ++E++   L+ +GITGPEGH+ S PEEVE EA  RA+ +A QANCPLYV  VMSKGAAD+++ A+R+G VVFGEPI A LGTDGSHY    W  AA +V SPP+  D  T+ HL  LL+SGDL+ TG+ HC F  +QKA+GKD+F  IP GVNG+E+RMSV+WEK V +G +D  +FVAVTSTNAAKIFN YP+KGR+ +GSDADLV+WNP   + ISA +H  NV++NIFEG+ C GV  +VIS G+VVLEDGNL V  G G+F+P   F ++V+ ++K R++  +   + V R  YDGPV ++        +     + +Q  A  S  ++   P+     R++  S F+LSG+Q DD++  R+  +   PPGG
Sbjct:    5 GKKSIP---RITSDRLLIKGGKIVNDDQSFHADLYVEDGLIKQIGENLIVPGGIKTIDAHGLMVLPGGVDVHTRLQMPVMGMTPADDFCQGTKAALAGGTTMILDHVFPDAGVSLLAAYEQWRERADSAACCDYSLHVDIPRWHESTKEELEALVRDKGVNSFLVFMAYKDRCQCTDGQIYEIFSLIRDLGAVAQVHAENGDIVEEEQKRLLEQGITGPEGHVLSHPEEVEAEAVYRAVTIAKQANCPLYVTKVMSKGAADMVAQAKRRGVVVFGEPITASLGTDGSHYWSKNWAKAAAFVTSPPINPDPTTADHLTSLLSSGDLQVTGSAHCTFTTAQKAVGKDNFTLIPEGVNGIEERMSVVWEKCVASGKMDENEFVAVTSTNAAKIFNFYPRKGRVAVGSDADLVIWNPRATKVISAKSHNLNVEYNIFEGVECRGVPTVVISQGRVVLEDGNLLVTPGAGRFIPRKTFPDFVYKRIKARNRLAEI--HGVPRGLYDGPVHEVM-------LPAKPGSGTQARASCSGKISVP-PV-----RNLHQSGFSLSGSQADDHIARRTAQKIMAPPGG 564          
BLAST of Dihydropyrimidinase vs. Ensembl Mouse
Match: Dpysl4 (dihydropyrimidinase-like 4 [Source:MGI Symbol;Acc:MGI:1349764])

HSP 1 Score: 623.239 bits (1606), Expect = 0.000e+0
Identity = 295/578 (51.04%), Postives = 404/578 (69.90%), Query Frame = 1
Query:  112 GVKKVPLHLQSSQNRLCIKGAKIVNDDRMFDADVYIEDGIIKQLGTNLVIPGGVRCVEANGKLLIPGGIDTHTHMEFPFMGTVSSDDFYSGTRAALAGGTTMIIDFVIGQKGTSLIDSYNQYREKADSKVCCDYGLHVIVSSYNESVGNEMEKLASEHGINSFKIFMAYKDSLMLEDDEMYEVFKKCKSIGALAQVHAENGKLIEKKSLELISKGITGPEGHLYSRPEEVECEATNRAIMLADQANCPLYVVHVMSKGAADIISDARRQGKVVFGEPIAAGLGTDGSHYSHSCWRHAAGYVMSPPLRNDRNTSKHLMQLLASGDLECTGTDHCVFKASQKALGKDDFRSIPNGVNGVEDRMSVIWEKGVVTGILDPCKFVAVTSTNAAKIFNIYPKKGRIDIGSDADLVLWNPDVRRTISASTHYQNVDFNIFEGMHCHGVAEMVISGGKVVLEDGNLRVAQGTGKFVPTNPFCNYVFNKVKLRDQCHKTLANKVERQPYDGPVEDLSKEMTNLNMNFDDDTDSQQNAISSEFVNTKRPLTSGGGRHMQDSSFALSGAQIDDNLPTRSGIRTRQPPGG 1845
            G K +P   + + +RL IKG KIVNDD+ F AD+Y+EDG+IKQ+G NL++PGG++ ++A+G +++PGG+D HT ++ P MG   +DDF  GT+AALAGGTTMI+D V    G SL+ +Y Q+RE+ADS  CCDY LHV +  ++ES   E+E L  + G+NSF +FMAYKD     D ++YE+F   + +GA+AQVHAENG ++E++   L+ +GITGPEGH+ S PEEVE EA  RA+ +A QANCPLYV  VMSKGAAD+++ A+R+G VVFGEPI A LGTDGSHY    W  AA +V SPP+  D  T+ HL  LL+SGDL+ TG+ HC F  +QKA+GKD+F  IP GVNG+E+RMSV+WEK V +G +D  +FVAVTSTNAAKIFN YP+KGR+ +GSDADLV+WNP   + ISA +H  NV++NIFEG+ C GV  +VIS G+VVLEDGNL V  G G+F+P   F ++V+ ++K R++  +   + V R  YDGPV ++        +     + +Q  A  S  ++   P+     R++  S F+LSG+Q DD++  R+  +   PPGG
Sbjct:    5 GKKSIP---RITSDRLLIKGGKIVNDDQSFHADLYVEDGLIKQIGENLIVPGGIKTIDAHGLMVLPGGVDVHTRLQMPVMGMTPADDFCQGTKAALAGGTTMILDHVFPDAGVSLLAAYEQWRERADSAACCDYSLHVDIPRWHESTKEELEALVRDKGVNSFLVFMAYKDRCQCTDGQIYEIFSLIRDLGAVAQVHAENGDIVEEEQKRLLEQGITGPEGHVLSHPEEVEAEAVYRAVTIAKQANCPLYVTKVMSKGAADMVAQAKRRGVVVFGEPITASLGTDGSHYWSKNWAKAAAFVTSPPINPDPTTADHLTSLLSSGDLQVTGSAHCTFTTAQKAVGKDNFTLIPEGVNGIEERMSVVWEKCVASGKMDENEFVAVTSTNAAKIFNFYPRKGRVAVGSDADLVIWNPRATKVISAKSHNLNVEYNIFEGVECRGVPTVVISQGRVVLEDGNLLVTPGAGRFIPRKTFPDFVYKRIKARNRLAEI--HGVPRGLYDGPVHEVM-------LPAKPGSGTQARASCSGKISVP-PV-----RNLHQSGFSLSGSQADDHIARRTAQKIMAPPGG 564          
BLAST of Dihydropyrimidinase vs. UniProt/SwissProt
Match: sp|Q90635|DPYL2_CHICK (Dihydropyrimidinase-related protein 2 OS=Gallus gallus OX=9031 GN=DPYSL2 PE=2 SV=1)

HSP 1 Score: 643.654 bits (1659), Expect = 0.000e+0
Identity = 309/585 (52.82%), Postives = 412/585 (70.43%), Query Frame = 1
Query:  112 GVKKVPLHLQSSQNRLCIKGAKIVNDDRMFDADVYIEDGIIKQLGTNLVIPGGVRCVEANGKLLIPGGIDTHTHMEFPFMGTVSSDDFYSGTRAALAGGTTMIIDFVIGQKGTSLIDSYNQYREKADSKVCCDYGLHVIVSSYNESVGNEMEKLASEHGINSFKIFMAYKDSLMLEDDEMYEVFKKCKSIGALAQVHAENGKLIEKKSLELISKGITGPEGHLYSRPEEVECEATNRAIMLADQANCPLYVVHVMSKGAADIISDARRQGKVVFGEPIAAGLGTDGSHYSHSCWRHAAGYVMSPPLRNDRNTSKHLMQLLASGDLECTGTDHCVFKASQKALGKDDFRSIPNGVNGVEDRMSVIWEKGVVTGILDPCKFVAVTSTNAAKIFNIYPKKGRIDIGSDADLVLWNPDVRRTISASTHYQNVDFNIFEGMHCHGVAEMVISGGKVVLEDGNLRVAQGTGKFVPTNPFCNYVFNKVKLRDQCHKTLANKVERQPYDGPVEDLSKEMTNLNMNFDDDTDSQQNAISSEFVNTKRPLTSGGGRHMQDSSFALSGAQIDDNLPTRSGIRTRQPPGGTA--TSL 1860
            G K +P   + + +RL IKG KIVNDD+ F AD+Y+EDG+IKQ+G NL++PGGV+ +EA+G+++IPGGID HT  + P  G  S+DDF+ GT+AALAGGTTMIID V+ + GTSL+ +++Q+RE ADSK CCDY LHV ++ +++ V  EME L  +HG+NSF ++MA+KD   L D ++YEV    + IGA AQVHAENG +I ++   ++  GITGPEGH+ SRPEEVE EA NRAI +A+Q NCPLY+  VMSK AA++I+ AR++G VV+GEPI A LGTDGSHY    W  AA +V SPPL  D  T   L  LL+ GDL+ TG+ HC F  +QKA+GKD+F  IP G NG E+RMS+IW+K VVTG +D  +FVAVTSTNAAKIFN+YP+KGRI +GSDADLV+W+PD  +TISA TH  ++++NIFEGM C G   +VIS GK+VLEDGNL V +G+G+++P  PF ++V+ ++K R +  +     V R  YDGPV ++S     +            +A +S       P+     R++  S F+LSGAQIDDN+P R+  R   PPGG A  TSL
Sbjct:    5 GKKNIP---RITSDRLLIKGGKIVNDDQSFYADIYMEDGLIKQIGENLIVPGGVKTIEAHGRMVIPGGIDVHTRFQMPEQGMTSADDFFQGTKAALAGGTTMIIDHVVPEPGTSLLTAFDQWREWADSKSCCDYSLHVDITEWHKGVQEEMEALVKDHGVNSFLVYMAFKDRFQLSDSQIYEVLSVIRDIGATAQVHAENGDIIAEEQQRILELGITGPEGHVLSRPEEVEAEAVNRAITIANQTNCPLYITKVMSKSAAEVIAQARKKGTVVYGEPITASLGTDGSHYWSKNWAKAAAFVTSPPLSPDPTTPDFLNSLLSCGDLQVTGSAHCTFNTAQKAVGKDNFTLIPEGTNGTEERMSIIWDKAVVTGKMDENQFVAVTSTNAAKIFNLYPRKGRIAVGSDADLVIWDPDSVKTISAKTHNISLEYNIFEGMECRGSPLVVISQGKIVLEDGNLHVTEGSGRYIPRKPFPDFVYKRIKARSRLAELRG--VPRGLYDGPVCEVSVTPKTVT--------PASSAKTSPAKQQAPPV-----RNLHQSGFSLSGAQIDDNIPRRTTQRIVAPPGGRANITSL 571          
BLAST of Dihydropyrimidinase vs. UniProt/SwissProt
Match: sp|Q63150|DPYS_RAT (Dihydropyrimidinase OS=Rattus norvegicus OX=10116 GN=Dpys PE=1 SV=2)

HSP 1 Score: 639.802 bits (1649), Expect = 0.000e+0
Identity = 307/516 (59.50%), Postives = 385/516 (74.61%), Query Frame = 1
Query:  142 SSQNRLCIKGAKIVNDDRMFDADVYIEDGIIKQLGTNLVIPG----GVRCVEANGKLLIPGGIDTHTHMEFPFMGTVSSDDFYSGTRAALAGGTTMIIDFVIGQKGTSLIDSYNQYREKADSKVCCDYGLHVIVSSYNESVGNEMEKLASEHGINSFKIFMAYKDSLMLEDDEMYEVFKKCKSIGALAQVHAENGKLIEKKSLELISKGITGPEGHLYSRPEEVECEATNRAIMLADQANCPLYVVHVMSKGAADIISDARRQGKVVFGEPIAAGLGTDGSHYSHSCWRHAAGYVMSPPLRNDRNTSKHLMQLLASGDLECTGTDHCVFKASQKALGKDDFRSIPNGVNGVEDRMSVIWEKGVVTGILDPCKFVAVTSTNAAKIFNIYPKKGRIDIGSDADLVLWNPDVRRTISASTHYQNVDFNIFEGMHCHGVAEMVISGGKVVLEDGNLRVAQGTGKFVPTNPFCNYVFNKVKLRDQCHKTLANKVERQPYDGPVEDLSKEMTNLNMNFDDDT 1677
            + Q RL I+G ++VNDD    ADV +EDG+++ LG +L+ PG    G+R ++A GKL++PGGIDTHTHM+FPFMG+ S DDF+ GT+AALAGGTTMIIDF I QKG+SLI+++  +R  AD KVCCDY LHV V+ +++ V  EM+ LA + G+NSFK+FMAYKD  M++D +MY  F +CK IGA+AQVHAENG LI + + ++++ GITGPEGH   RPE VE EAT RAI +A   NCPLY+VHVMSK AA +I+DA+R+GKVV+GEPIAAGLGTDG+ Y +  WRHAA +VM PPLR D +T   LM LLA+GDL  TG+D+C F   QKALGKDDF  IPNGVNGVEDRMSVIWEKGV +G +D  +FVAVTSTNAAKIFN+YPKKGRI +GSDAD+V+W+P+  RTISA TH+Q V+FNIFEGM CHGV  + IS G+VV E G   V  G GKF+P  PF  +++ +VK RDQ    +   V+R PY G V  L    T      +DDT
Sbjct:    2 APQERLLIRGGRVVNDDFSQVADVLVEDGVVRALGRDLLPPGDTSRGLRILDAAGKLVLPGGIDTHTHMQFPFMGSQSVDDFHQGTKAALAGGTTMIIDFAIPQKGSSLIEAFETWRNWADPKVCCDYSLHVAVTWWSDKVKEEMKTLAQDKGVNSFKMFMAYKDLYMVQDQQMYAAFSQCKEIGAIAQVHAENGDLIAEGAKKMLALGITGPEGHELCRPEAVEAEATLRAITIASAVNCPLYIVHVMSKSAAKVIADAKREGKVVYGEPIAAGLGTDGTQYWNKEWRHAAHHVMGPPLRPDPSTPGFLMNLLANGDLTTTGSDNCTFNTCQKALGKDDFTKIPNGVNGVEDRMSVIWEKGVHSGKMDENRFVAVTSTNAAKIFNLYPKKGRIAVGSDADIVIWDPEATRTISAKTHHQAVNFNIFEGMVCHGVPLVTISRGRVVYEAGVFDVTAGHGKFIPRQPFAEFIYKRVKQRDQTCTPIP--VKRAPYKGEVITLKPRETK-----EDDT 510          
BLAST of Dihydropyrimidinase vs. UniProt/SwissProt
Match: sp|P47942|DPYL2_RAT (Dihydropyrimidinase-related protein 2 OS=Rattus norvegicus OX=10116 GN=Dpysl2 PE=1 SV=1)

HSP 1 Score: 639.417 bits (1648), Expect = 0.000e+0
Identity = 306/585 (52.31%), Postives = 410/585 (70.09%), Query Frame = 1
Query:  112 GVKKVPLHLQSSQNRLCIKGAKIVNDDRMFDADVYIEDGIIKQLGTNLVIPGGVRCVEANGKLLIPGGIDTHTHMEFPFMGTVSSDDFYSGTRAALAGGTTMIIDFVIGQKGTSLIDSYNQYREKADSKVCCDYGLHVIVSSYNESVGNEMEKLASEHGINSFKIFMAYKDSLMLEDDEMYEVFKKCKSIGALAQVHAENGKLIEKKSLELISKGITGPEGHLYSRPEEVECEATNRAIMLADQANCPLYVVHVMSKGAADIISDARRQGKVVFGEPIAAGLGTDGSHYSHSCWRHAAGYVMSPPLRNDRNTSKHLMQLLASGDLECTGTDHCVFKASQKALGKDDFRSIPNGVNGVEDRMSVIWEKGVVTGILDPCKFVAVTSTNAAKIFNIYPKKGRIDIGSDADLVLWNPDVRRTISASTHYQNVDFNIFEGMHCHGVAEMVISGGKVVLEDGNLRVAQGTGKFVPTNPFCNYVFNKVKLRDQCHKTLANKVERQPYDGPVEDLSKEMTNLNMNFDDDTDSQQNAISSEFVNTKRPLTSGGGRHMQDSSFALSGAQIDDNLPTRSGIRTRQPPGGTA--TSL 1860
            G K +P   + + +RL IKG KIVNDD+ F AD+Y+EDG+IKQ+G NL++PGGV+ +EA+ +++IPGGID HT  + P  G  S+DDF+ GT+AALAGGTTMIID V+ + GTSL+ +++Q+RE ADSK CCDY LHV ++ +++ +  EME L  +HG+NSF ++MA+KD   L D ++YEV    + IGA+AQVHAENG +I ++   ++  GITGPEGH+ SRPEEVE EA NR+I +A+Q NCPLYV  VMSK AA++I+ AR++G VV+GEPI A LGTDGSHY    W  AA +V SPPL  D  T   L  LL+ GDL+ TG+ HC F  +QKA+GKD+F  IP G NG E+RMSVIW+K VVTG +D  +FVAVTSTNAAK+FN+YP+KGRI +GSDADLV+W+PD  +TISA TH   +++NIFEGM C G   +VIS GK+VLEDG L V +G+G+++P  PF ++V+ ++K R +  +     V R  YDGPV ++S     +            +A +S       P+     R++  S F+LSGAQIDDN+P R+  R   PPGG A  TSL
Sbjct:    5 GKKNIP---RITSDRLLIKGGKIVNDDQSFYADIYMEDGLIKQIGENLIVPGGVKTIEAHSRMVIPGGIDVHTRFQMPDQGMTSADDFFQGTKAALAGGTTMIIDHVVPEPGTSLLAAFDQWREWADSKSCCDYSLHVDITEWHKGIQEEMEALVKDHGVNSFLVYMAFKDRFQLTDSQIYEVLSVIRDIGAIAQVHAENGDIIAEEQQRILDLGITGPEGHVLSRPEEVEAEAVNRSITIANQTNCPLYVTKVMSKSAAEVIAQARKKGTVVYGEPITASLGTDGSHYWSKNWAKAAAFVTSPPLSPDPTTPDFLNSLLSCGDLQVTGSAHCTFNTAQKAVGKDNFTLIPEGTNGTEERMSVIWDKAVVTGKMDENQFVAVTSTNAAKVFNLYPRKGRISVGSDADLVIWDPDSVKTISAKTHNSALEYNIFEGMECRGSPLVVISQGKIVLEDGTLHVTEGSGRYIPRKPFPDFVYKRIKARSRLAEL--RGVPRGLYDGPVCEVSVTPKTVT--------PASSAKTSPAKQQAPPV-----RNLHQSGFSLSGAQIDDNIPRRTTQRIVAPPGGRANITSL 571          
BLAST of Dihydropyrimidinase vs. UniProt/SwissProt
Match: sp|O08553|DPYL2_MOUSE (Dihydropyrimidinase-related protein 2 OS=Mus musculus OX=10090 GN=Dpysl2 PE=1 SV=2)

HSP 1 Score: 639.417 bits (1648), Expect = 0.000e+0
Identity = 306/585 (52.31%), Postives = 410/585 (70.09%), Query Frame = 1
Query:  112 GVKKVPLHLQSSQNRLCIKGAKIVNDDRMFDADVYIEDGIIKQLGTNLVIPGGVRCVEANGKLLIPGGIDTHTHMEFPFMGTVSSDDFYSGTRAALAGGTTMIIDFVIGQKGTSLIDSYNQYREKADSKVCCDYGLHVIVSSYNESVGNEMEKLASEHGINSFKIFMAYKDSLMLEDDEMYEVFKKCKSIGALAQVHAENGKLIEKKSLELISKGITGPEGHLYSRPEEVECEATNRAIMLADQANCPLYVVHVMSKGAADIISDARRQGKVVFGEPIAAGLGTDGSHYSHSCWRHAAGYVMSPPLRNDRNTSKHLMQLLASGDLECTGTDHCVFKASQKALGKDDFRSIPNGVNGVEDRMSVIWEKGVVTGILDPCKFVAVTSTNAAKIFNIYPKKGRIDIGSDADLVLWNPDVRRTISASTHYQNVDFNIFEGMHCHGVAEMVISGGKVVLEDGNLRVAQGTGKFVPTNPFCNYVFNKVKLRDQCHKTLANKVERQPYDGPVEDLSKEMTNLNMNFDDDTDSQQNAISSEFVNTKRPLTSGGGRHMQDSSFALSGAQIDDNLPTRSGIRTRQPPGGTA--TSL 1860
            G K +P   + + +RL IKG KIVNDD+ F AD+Y+EDG+IKQ+G NL++PGGV+ +EA+ +++IPGGID HT  + P  G  S+DDF+ GT+AALAGGTTMIID V+ + GTSL+ +++Q+RE ADSK CCDY LHV ++ +++ +  EME L  +HG+NSF ++MA+KD   L D ++YEV    + IGA+AQVHAENG +I ++   ++  GITGPEGH+ SRPEEVE EA NR+I +A+Q NCPLYV  VMSK AA++I+ AR++G VV+GEPI A LGTDGSHY    W  AA +V SPPL  D  T   L  LL+ GDL+ TG+ HC F  +QKA+GKD+F  IP G NG E+RMSVIW+K VVTG +D  +FVAVTSTNAAK+FN+YP+KGRI +GSDADLV+W+PD  +TISA TH   +++NIFEGM C G   +VIS GK+VLEDG L V +G+G+++P  PF ++V+ ++K R +  +     V R  YDGPV ++S     +            +A +S       P+     R++  S F+LSGAQIDDN+P R+  R   PPGG A  TSL
Sbjct:    5 GKKNIP---RITSDRLLIKGGKIVNDDQSFYADIYMEDGLIKQIGENLIVPGGVKTIEAHSRMVIPGGIDVHTRFQMPDQGMTSADDFFQGTKAALAGGTTMIIDHVVPEPGTSLLAAFDQWREWADSKSCCDYSLHVDITEWHKGIQEEMEALVKDHGVNSFLVYMAFKDRFQLTDSQIYEVLSVIRDIGAIAQVHAENGDIIAEEQQRILDLGITGPEGHVLSRPEEVEAEAVNRSITIANQTNCPLYVTKVMSKSAAEVIAQARKKGTVVYGEPITASLGTDGSHYWSKNWAKAAAFVTSPPLSPDPTTPDFLNSLLSCGDLQVTGSAHCTFNTAQKAVGKDNFTLIPEGTNGTEERMSVIWDKAVVTGKMDENQFVAVTSTNAAKVFNLYPRKGRISVGSDADLVIWDPDSVKTISAKTHNSALEYNIFEGMECRGSPLVVISQGKIVLEDGTLHVTEGSGRYIPRKPFPDFVYKRIKARSRLAEL--RGVPRGLYDGPVCEVSVTPKTVT--------PASSAKTSPAKQQAPPV-----RNLHQSGFSLSGAQIDDNIPRRTTQRIVAPPGGRANITSL 571          
BLAST of Dihydropyrimidinase vs. UniProt/SwissProt
Match: sp|O02675|DPYL2_BOVIN (Dihydropyrimidinase-related protein 2 OS=Bos taurus OX=9913 GN=DPYSL2 PE=1 SV=1)

HSP 1 Score: 639.417 bits (1648), Expect = 0.000e+0
Identity = 306/585 (52.31%), Postives = 411/585 (70.26%), Query Frame = 1
Query:  112 GVKKVPLHLQSSQNRLCIKGAKIVNDDRMFDADVYIEDGIIKQLGTNLVIPGGVRCVEANGKLLIPGGIDTHTHMEFPFMGTVSSDDFYSGTRAALAGGTTMIIDFVIGQKGTSLIDSYNQYREKADSKVCCDYGLHVIVSSYNESVGNEMEKLASEHGINSFKIFMAYKDSLMLEDDEMYEVFKKCKSIGALAQVHAENGKLIEKKSLELISKGITGPEGHLYSRPEEVECEATNRAIMLADQANCPLYVVHVMSKGAADIISDARRQGKVVFGEPIAAGLGTDGSHYSHSCWRHAAGYVMSPPLRNDRNTSKHLMQLLASGDLECTGTDHCVFKASQKALGKDDFRSIPNGVNGVEDRMSVIWEKGVVTGILDPCKFVAVTSTNAAKIFNIYPKKGRIDIGSDADLVLWNPDVRRTISASTHYQNVDFNIFEGMHCHGVAEMVISGGKVVLEDGNLRVAQGTGKFVPTNPFCNYVFNKVKLRDQCHKTLANKVERQPYDGPVEDLSKEMTNLNMNFDDDTDSQQNAISSEFVNTKRPLTSGGGRHMQDSSFALSGAQIDDNLPTRSGIRTRQPPGGTA--TSL 1860
            G K +P   + + +RL IKG KIVNDD+ F AD+Y+EDG+IKQ+G NL++PGGV+ +EA+ +++IPGGID HT  + P  G  S+DDF+ GT+AALAGGTTMIID V+ + GTSL+ +++Q+RE ADSK CCDY LHV ++ +++ V  EME L  +HG+NSF ++MA+KD   L D ++YEV    + IGA+AQVHAENG +I ++   ++  GITGPEGH+ SRPEEVE EA NR+I +A+Q NCPLY+  VMSK AA++I+ AR++G VV+GEPI A LGTDGSHY    W  AA +V SPPL  D  T   L  LL+ GDL+ TG+ HC F  +QKA+GKD+F  IP G NG E+RMSVIW+K VVTG +D  +FVAVTSTNAAK+FN+YP+KGRI +GSDADLV+W+PD  +TISA TH  ++++NIFEGM C G   +VIS GK+VLEDG L V +G+G+++P  PF ++V+ ++K R +  +     V R  YDGPV ++S     +            +A +S       P+     R++  S F+LSGAQIDDN+P R+  R   PPGG A  TSL
Sbjct:    5 GKKNIP---RITSDRLLIKGGKIVNDDQSFYADIYMEDGLIKQIGENLIVPGGVKTIEAHSRMVIPGGIDVHTRFQMPDQGMTSADDFFQGTKAALAGGTTMIIDHVVPEPGTSLLAAFDQWREWADSKSCCDYSLHVDITEWHKGVQEEMEALVKDHGVNSFLVYMAFKDRFQLTDSQIYEVLSVIRDIGAIAQVHAENGDIIAEEQQRILDLGITGPEGHVLSRPEEVEAEAVNRSITIANQTNCPLYITKVMSKSAAEVIAQARKKGTVVYGEPITASLGTDGSHYWSKNWAKAAAFVTSPPLSPDPTTPDFLNSLLSCGDLQVTGSAHCTFNTAQKAVGKDNFTLIPEGTNGTEERMSVIWDKAVVTGKMDENQFVAVTSTNAAKVFNLYPRKGRIAVGSDADLVIWDPDSVKTISAKTHNSSLEYNIFEGMECRGSPLVVISQGKIVLEDGTLHVTEGSGRYIPRKPFPDFVYKRIKARSRLAEL--RGVPRGLYDGPVCEVSVTPKTVT--------PASSAKTSPAKQQAPPV-----RNLHQSGFSLSGAQIDDNIPRRTTQRIVAPPGGRANITSL 571          
BLAST of Dihydropyrimidinase vs. TrEMBL
Match: A0A0X3NYF8 (Dihydropyrimidinase (Fragment) OS=Schistocephalus solidus OX=70667 GN=DPYS PE=4 SV=1)

HSP 1 Score: 841.647 bits (2173), Expect = 0.000e+0
Identity = 401/601 (66.72%), Postives = 478/601 (79.53%), Query Frame = 1
Query:   67 FLLKIIKMNDSKVNIGVKKVPLHLQSSQNRLCIKGAKIVNDDRMFDADVYIEDGIIKQLGTNLVIPGGVRCVEANGKLLIPGGIDTHTHMEFPFMGTVSSDDFYSGTRAALAGGTTMIIDFVIGQKGTSLIDSYNQYREKADSKVCCDYGLHVIVSSYNESVGNEMEKLASEHGINSFKIFMAYKDSLMLEDDEMYEVFKKCKSIGALAQVHAENGKLIEKKSLELISKGITGPEGHLYSRPEEVECEATNRAIMLADQANCPLYVVHVMSKGAADIISDARRQGKVVFGEPIAAGLGTDGSHYSHSCWRHAAGYVMSPPLRNDRNTSKHLMQLLASGDLECTGTDHCVFKASQKALGKDDFRSIPNGVNGVEDRMSVIWEKGVVTGILDPCKFVAVTSTNAAKIFNIYPKKGRIDIGSDADLVLWNPDVRRTISASTHYQNVDFNIFEGMHCHGVAEMVISGGKVVLEDGNLRVAQGTGKFVPTNPFCNYVFNKVKLRDQCHKTLANKVERQPYDGPVEDLSKEM--TNLNMNFDDDTDSQQNAISSEFVNTKRPLTSGGGRHMQDSSFALSGAQIDDNLPTRSGIRTRQPPGGTATSLW 1863
            FL   + MN SKV++G  K+PLHLQS+QNRL +KG  +VNDDR F AD+YIEDG+IKQ+GTNL IPGGVR V+  GKL++PGGIDTHTHME PFMGT SSDDFYSGT+AALAGGTTMIIDFV   +G+S++++Y QYREKADSKVCCDY LHVIV  ++E + NEME L  E GINSFK F+AY    MLEDDE+Y+ F +C+ +GALAQVHAENGKLI +K  E+I  GI GPEGH +SRPE  E EAT+RAI LAD ANCPLYVVHVMS  AA+ I++AR+ G +V GE +AAGLGTDGSHY   CWR AAGYVMSPPLR +  T + LM+ LA+G LECTGTDHCVFKA QKALGKDDFR IPNGVNGVEDRMSVIWEKGVV+GI+DPCKFVA+TSTNAAKIFNIYP+KGRI++GSDAD+V+W+P+  RTISASTH+QNVDFNIFEGM CHGV  +VI+ G VVLED +L+V+QGTG+FVPT PF  YV+ K++ R +  + +   V R+PY GPV DL   +  T++   F +    Q  A      N +RP TS GGR+MQDSSFALSG+Q+DD LP RS IRT+QPPGG + SLW
Sbjct:   26 FLSLGLVMNSSKVSVGAGKLPLHLQSAQNRLHLKGGTVVNDDRKFVADIYIEDGVIKQVGTNLSIPGGVRTVDVRGKLVMPGGIDTHTHMEMPFMGTHSSDDFYSGTKAALAGGTTMIIDFVCPARGSSILEAYEQYREKADSKVCCDYALHVIVPHFDEKLSNEMEVLTKEKGINSFKSFLAYPGVFMLEDDELYDFFCRCRELGALAQVHAENGKLISRKQEEVIQHGILGPEGHPFSRPEAAEVEATSRAITLADTANCPLYVVHVMSALAANKIAEARQDGILVIGEAVAAGLGTDGSHYLDKCWRSAAGYVMSPPLRMNPETPRLLMKALANGHLECTGTDHCVFKADQKALGKDDFRKIPNGVNGVEDRMSVIWEKGVVSGIIDPCKFVAITSTNAAKIFNIYPRKGRIEVGSDADIVVWDPEAERTISASTHHQNVDFNIFEGMRCHGVPLIVITNGHVVLEDDDLKVSQGTGRFVPTPPFSPYVYAKIEGRQKLRERI--PVAREPYTGPVADLGAALQATDIKTVFANGKGDQAQAF-----NRQRPPTSAGGRNMQDSSFALSGSQVDDALPVRSTIRTQQPPGGASRSLW 619          
BLAST of Dihydropyrimidinase vs. TrEMBL
Match: A0A3P7D5Z0 (Amidohydro-rel domain-containing protein OS=Schistocephalus solidus OX=70667 GN=SSLN_LOCUS15650 PE=4 SV=1)

HSP 1 Score: 839.721 bits (2168), Expect = 0.000e+0
Identity = 399/594 (67.17%), Postives = 475/594 (79.97%), Query Frame = 1
Query:   88 MNDSKVNIGVKKVPLHLQSSQNRLCIKGAKIVNDDRMFDADVYIEDGIIKQLGTNLVIPGGVRCVEANGKLLIPGGIDTHTHMEFPFMGTVSSDDFYSGTRAALAGGTTMIIDFVIGQKGTSLIDSYNQYREKADSKVCCDYGLHVIVSSYNESVGNEMEKLASEHGINSFKIFMAYKDSLMLEDDEMYEVFKKCKSIGALAQVHAENGKLIEKKSLELISKGITGPEGHLYSRPEEVECEATNRAIMLADQANCPLYVVHVMSKGAADIISDARRQGKVVFGEPIAAGLGTDGSHYSHSCWRHAAGYVMSPPLRNDRNTSKHLMQLLASGDLECTGTDHCVFKASQKALGKDDFRSIPNGVNGVEDRMSVIWEKGVVTGILDPCKFVAVTSTNAAKIFNIYPKKGRIDIGSDADLVLWNPDVRRTISASTHYQNVDFNIFEGMHCHGVAEMVISGGKVVLEDGNLRVAQGTGKFVPTNPFCNYVFNKVKLRDQCHKTLANKVERQPYDGPVEDLSKEM--TNLNMNFDDDTDSQQNAISSEFVNTKRPLTSGGGRHMQDSSFALSGAQIDDNLPTRSGIRTRQPPGGTATSLW 1863
            MN SKV++G  K+PLHLQS+QNRL +KG  +VNDDR F AD+YIEDG+IKQ+GTNL IPGGVR V+  GKL++PGGIDTHTHME PFMGT SSDDFYSGT+AALAGGTTMIIDFV   +G+S++++Y QYREKADSKVCCDY LHVIV  ++E + NEME L  E GINSFK F+AY    MLEDDE+Y+ F +C+ +GALAQVHAENGKLI +K  E+I  GI GPEGH +SRPE  E EAT+RAI LAD ANCPLYVVHVMS  AA+ I++AR+ G +V GE +AAGLGTDGSHY   CWR AAGYVMSPPLR +  T + LM+ LA+G LECTGTDHCVFKA QKALGKDDFR IPNGVNGVEDRMSVIWEKGVV+GI+DPCKFVA+TSTNAAKIFNIYP+KGRI++GSDAD+V+W+P+  RTISASTH+QNVDFNIFEGM CHGV  +VI+ G VVLED +L+V+QGTG+FVPT PF  YV+ K++ R +  + +   V R+PY GPV DL   +  T++   F +    Q  A      N +RP TS GGR+MQDSSFALSG+Q+DD LP RS IRT+QPPGG + SLW
Sbjct:    3 MNSSKVSVGAGKLPLHLQSAQNRLHLKGGTVVNDDRKFVADIYIEDGVIKQVGTNLSIPGGVRTVDVRGKLVMPGGIDTHTHMEMPFMGTHSSDDFYSGTKAALAGGTTMIIDFVCPARGSSILEAYEQYREKADSKVCCDYALHVIVPHFDEKLSNEMEVLTKEKGINSFKSFLAYPGVFMLEDDELYDFFCRCRELGALAQVHAENGKLISRKQEEVIQHGILGPEGHPFSRPEAAEVEATSRAITLADTANCPLYVVHVMSALAANKIAEARQDGILVIGEAVAAGLGTDGSHYLDKCWRSAAGYVMSPPLRMNPETPRLLMKALANGHLECTGTDHCVFKADQKALGKDDFRKIPNGVNGVEDRMSVIWEKGVVSGIIDPCKFVAITSTNAAKIFNIYPRKGRIEVGSDADIVVWDPEAERTISASTHHQNVDFNIFEGMRCHGVPLIVITNGHVVLEDDDLKVSQGTGRFVPTPPFSPYVYAKIEGRQKLRERI--PVAREPYTGPVADLGAALQATDIKTVFANGKGDQAQAF-----NRQRPPTSAGGRNMQDSSFALSGSQVDDALPVRSTIRTQQPPGGASRSLW 589          
BLAST of Dihydropyrimidinase vs. TrEMBL
Match: A0A183TGQ2 (Dihydropyrimidinase OS=Schistocephalus solidus OX=70667 PE=4 SV=1)

HSP 1 Score: 839.721 bits (2168), Expect = 0.000e+0
Identity = 399/594 (67.17%), Postives = 475/594 (79.97%), Query Frame = 1
Query:   88 MNDSKVNIGVKKVPLHLQSSQNRLCIKGAKIVNDDRMFDADVYIEDGIIKQLGTNLVIPGGVRCVEANGKLLIPGGIDTHTHMEFPFMGTVSSDDFYSGTRAALAGGTTMIIDFVIGQKGTSLIDSYNQYREKADSKVCCDYGLHVIVSSYNESVGNEMEKLASEHGINSFKIFMAYKDSLMLEDDEMYEVFKKCKSIGALAQVHAENGKLIEKKSLELISKGITGPEGHLYSRPEEVECEATNRAIMLADQANCPLYVVHVMSKGAADIISDARRQGKVVFGEPIAAGLGTDGSHYSHSCWRHAAGYVMSPPLRNDRNTSKHLMQLLASGDLECTGTDHCVFKASQKALGKDDFRSIPNGVNGVEDRMSVIWEKGVVTGILDPCKFVAVTSTNAAKIFNIYPKKGRIDIGSDADLVLWNPDVRRTISASTHYQNVDFNIFEGMHCHGVAEMVISGGKVVLEDGNLRVAQGTGKFVPTNPFCNYVFNKVKLRDQCHKTLANKVERQPYDGPVEDLSKEM--TNLNMNFDDDTDSQQNAISSEFVNTKRPLTSGGGRHMQDSSFALSGAQIDDNLPTRSGIRTRQPPGGTATSLW 1863
            MN SKV++G  K+PLHLQS+QNRL +KG  +VNDDR F AD+YIEDG+IKQ+GTNL IPGGVR V+  GKL++PGGIDTHTHME PFMGT SSDDFYSGT+AALAGGTTMIIDFV   +G+S++++Y QYREKADSKVCCDY LHVIV  ++E + NEME L  E GINSFK F+AY    MLEDDE+Y+ F +C+ +GALAQVHAENGKLI +K  E+I  GI GPEGH +SRPE  E EAT+RAI LAD ANCPLYVVHVMS  AA+ I++AR+ G +V GE +AAGLGTDGSHY   CWR AAGYVMSPPLR +  T + LM+ LA+G LECTGTDHCVFKA QKALGKDDFR IPNGVNGVEDRMSVIWEKGVV+GI+DPCKFVA+TSTNAAKIFNIYP+KGRI++GSDAD+V+W+P+  RTISASTH+QNVDFNIFEGM CHGV  +VI+ G VVLED +L+V+QGTG+FVPT PF  YV+ K++ R +  + +   V R+PY GPV DL   +  T++   F +    Q  A      N +RP TS GGR+MQDSSFALSG+Q+DD LP RS IRT+QPPGG + SLW
Sbjct:    3 MNSSKVSVGAGKLPLHLQSAQNRLHLKGGTVVNDDRKFVADIYIEDGVIKQVGTNLSIPGGVRTVDVRGKLVMPGGIDTHTHMEMPFMGTHSSDDFYSGTKAALAGGTTMIIDFVCPARGSSILEAYEQYREKADSKVCCDYALHVIVPHFDEKLSNEMEVLTKEKGINSFKSFLAYPGVFMLEDDELYDFFCRCRELGALAQVHAENGKLISRKQEEVIQHGILGPEGHPFSRPEAAEVEATSRAITLADTANCPLYVVHVMSALAANKIAEARQDGILVIGEAVAAGLGTDGSHYLDKCWRSAAGYVMSPPLRMNPETPRLLMKALANGHLECTGTDHCVFKADQKALGKDDFRKIPNGVNGVEDRMSVIWEKGVVSGIIDPCKFVAITSTNAAKIFNIYPRKGRIEVGSDADIVVWDPEAERTISASTHHQNVDFNIFEGMRCHGVPLIVITNGHVVLEDDDLKVSQGTGRFVPTPPFSPYVYAKIEGRQKLRERI--PVAREPYTGPVADLGAALQATDIKTVFANGKGDQAQAF-----NRQRPPTSAGGRNMQDSSFALSGSQVDDALPVRSTIRTQQPPGGASRSLW 589          
BLAST of Dihydropyrimidinase vs. TrEMBL
Match: A0A0R3W2S3 (Amidohydro-rel domain-containing protein OS=Taenia asiatica OX=60517 GN=TASK_LOCUS4158 PE=4 SV=1)

HSP 1 Score: 814.683 bits (2103), Expect = 0.000e+0
Identity = 387/599 (64.61%), Postives = 475/599 (79.30%), Query Frame = 1
Query:   88 MNDSKVNIGVKKVPLHLQSSQNRLCIKGAKIVNDDRMFDADVYIEDGIIKQLGTNLVIPGGVRCVEANGKLLIPGGIDTHTHMEFPFMGTVSSDDFYSGTRAALAGGTTMIIDFVIGQKGTSLIDSYNQYREKADSKVCCDYGLHVIVSSYNESVGNEMEKLASEHGINSFKIFMAYKDSLMLEDDEMYEVFKKCKSIGALAQVHAENGKLIEKKSLELISKGITGPEGHLYSRPEEVECEATNRAIMLADQANCPLYVVHVMSKGAADIISDARRQGKVVFGEPIAAGLGTDGSHYSHSCWRHAAGYVMSPPLRNDRNTSKHLMQLLASGDLECTGTDHCVFKASQKALGKDDFRSIPNGVNGVEDRMSVIWEKGVVTGILDPCKFVAVTSTNAAKIFNIYPKKGRIDIGSDADLVLWNPDVRRTISASTHYQNVDFNIFEGMHCHGVAEMVISGGKVVL-EDGNLRVAQGTGKFVPTNPFCNYVFNKVKLRDQCHKTLANKVERQPYDGPVEDLSKEMTNLNMNFDDDT------DSQQNAISSEFVNTKRPLTSGGGRHMQDSSFALSGAQIDDNLPTRSGIRTRQPPGGTATSLW 1863
            MN SKVN+G  K+  HLQ++QNRL +KG  +VNDDRMF ADVY+EDGII+Q+G NL IPGGVR ++  GKL++PGGID+HTHM+ PFMGT S+DDFYSGT+AALAGGTTMIIDFV  ++G+S++++Y  YR+ ADSKVCCDY LHVIV  ++  V  EM  L  E G+NSFK F+AY D  MLEDD++Y+ F +C+ +GA+AQVHAENGKLI +K  E++ KGI GPEGH YSRPEE E EAT RAI LAD ANCPLYVVHVMS GAA  ISDAR+ G +V GE IAAGLGT+ SHY ++CWRHAAGYVMSPPLR+    SK LM+ LA+G LECTGTDHCVFKA QKALGKDDFR IPNGVNGVEDRMSVIWEKGV  GI+DPCKFVA+TSTNAAK+FNIYP+KGRID+GSDAD+V+W+ +  RTISASTH+QNVDFNIFEGM CHGV ++VI+ G VV+ EDG L+V+QGTG+F+PT  F  YV++KVK R +  +     V+R+PY GPV DLS  + ++++N           D Q+++  S+F    RP TS G R+MQDSSF+LSG+Q DD+LP+R+  RT QPPGG ++SLW
Sbjct:    1 MNTSKVNVGAGKLSHHLQNAQNRLLLKGGTVVNDDRMFPADVYVEDGIIRQVGLNLTIPGGVRTIDVQGKLVMPGGIDSHTHMQMPFMGTYSADDFYSGTKAALAGGTTMIIDFVCPKRGSSILEAYEHYRQNADSKVCCDYALHVIVPHFDNKVAEEMGILTKEKGVNSFKSFLAYPDVFMLEDDQLYDFFVRCRELGAIAQVHAENGKLIARKQEEVVKKGILGPEGHSYSRPEECEIEATGRAITLADAANCPLYVVHVMSAGAAQNISDARQAGILVIGEAIAAGLGTNNSHYFNTCWRHAAGYVMSPPLRSSGTESK-LMKALANGHLECTGTDHCVFKADQKALGKDDFRRIPNGVNGVEDRMSVIWEKGVAKGIIDPCKFVAITSTNAAKVFNIYPRKGRIDVGSDADIVVWDGEATRTISASTHHQNVDFNIFEGMVCHGVPQIVITNGHVVVEEDGALKVSQGTGRFIPTPAFSPYVYSKVKARSKLREV--EPVKREPYTGPVIDLSAALQSMDVNKSGVVANAAGGDQQKDSQFSQF--HHRPPTSSGSRNMQDSSFSLSGSQFDDSLPSRTSTRTMQPPGGKSSSLW 594          
BLAST of Dihydropyrimidinase vs. TrEMBL
Match: A0A075A1G2 (Amidohydro-rel domain-containing protein OS=Opisthorchis viverrini OX=6198 GN=T265_00672 PE=4 SV=1)

HSP 1 Score: 813.913 bits (2101), Expect = 0.000e+0
Identity = 392/598 (65.55%), Postives = 460/598 (76.92%), Query Frame = 1
Query:   88 MNDSKVNIGVKKVPLHLQSSQNRLCIKGAKIVNDDRMFDADVYIEDGIIKQLGTNLVIPGGVRCVEANGKLLIPGGIDTHTHMEFPFMGTVSSDDFYSGTRAALAGGTTMIIDFVIGQKGTSLIDSYNQYREKADSKVCCDYGLHVIVSSYNESVGNEMEKLASEHGINSFKIFMAYKDSLMLEDDEMYEVFKKCKSIGALAQVHAENGKLIEKKSLELISKGITGPEGHLYSRPEEVECEATNRAIMLADQANCPLYVVHVMSKGAADIISDARRQGKVVFGEPIAAGLGTDGSHYSHSCWRHAAGYVMSPPLRNDRNTSKHLMQLLASGDLECTGTDHCVFKASQKALGKDDFRSIPNGVNGVEDRMSVIWEKGVVTGILDPCKFVAVTSTNAAKIFNIYPKKGRIDIGSDADLVLWNPDVRRTISASTHYQNVDFNIFEGMHCHGVAEMVISGGKVVLEDGNLRVAQGTGKFVPTNPFCNYVFNKVKLRDQCHKTLANKVERQPYDGPVEDLSKEMTNLNMNFDDDTDSQQNAISSEFVNTK------RPLTSGGGRHMQDSSFALSGAQIDDNLPTRSGIRTRQPPGGTATSLW 1863
            MNDSK+ +G+KK+P+HLQSSQNRL IKG KIVNDDR F  D+YIEDGIIKQ+GT L IPGGVR ++A GKL+IPGGIDTHTH++ PFMG+VSSDDFYSGT+AA+AGGTT IIDFV   KGTSL+  Y QYRE ADSKVCCDYGLHVIV  +NE V  EME L  E G+NSFKIF+AY DSL+LEDDE+++VF+ CK +GALA  HAENGKLI+    E+   GITGPEGHLYSRPEE E EAT+R + +AD A CPLYVVHVMS  AA +ISDAR +G VV GE +A+ LGTDG +Y  +CWRHAAG+VMSPPLR D N S  LM+ L  G+LE TGTDHCVFK  QKA+GKDDFR IPNGVNG+EDRMSVIWEKGVV GILDPCKFVAVTSTNAAKIFN+YP+KGRID+GSDADLV+W+ +  RTISASTH+QNVDFNIFEGM CHGV   V+SGG+VVLEDG LRV QG G+F+P  PF  YV++++K  ++        +ER PY GPV        +      D +   +N   +E V         R  T GGGR+MQ+SSF+LSGAQI D+   R+ IRTRQPPGG A  LW
Sbjct:    1 MNDSKIQVGLKKLPIHLQSSQNRLLIKGGKIVNDDRSFHGDIYIEDGIIKQVGTQLTIPGGVRIIDAAGKLVIPGGIDTHTHLQMPFMGSVSSDDFYSGTKAAIAGGTTTIIDFVNPSKGTSLLKMYEQYREWADSKVCCDYGLHVIVPHFNEQVAKEMEILVKEKGVNSFKIFLAYADSLLLEDDEVFQVFRVCKRLGALAMAHAENGKLIKLLQDEIFQSGITGPEGHLYSRPEEAEIEATSRVVTIADAAGCPLYVVHVMSALAAKLISDARHRGSVVMGEAVASALGTDGRNYLDACWRHAAGHVMSPPLRPDPNNSVELMKCLGHGELETTGTDHCVFKTEQKAMGKDDFRKIPNGVNGIEDRMSVIWEKGVVPGILDPCKFVAVTSTNAAKIFNLYPRKGRIDVGSDADLVIWDGEATRTISASTHHQNVDFNIFEGMRCHGVPVTVLSGGRVVLEDGELRVTQGAGRFLPCAPFPPYVYDRLKPLEKARAV--TLIERPPYTGPV--------STEFCLTDSSSPVKNGQVAEAVGANGDGPRLRAPTCGGGRNMQESSFSLSGAQIGDDHHVRTTIRTRQPPGGAANPLW 588          
BLAST of Dihydropyrimidinase vs. Ensembl Cavefish
Match: dpysl2b (dihydropyrimidinase-related protein 2 [Source:NCBI gene;Acc:103036518])

HSP 1 Score: 637.876 bits (1644), Expect = 0.000e+0
Identity = 303/585 (51.79%), Postives = 410/585 (70.09%), Query Frame = 1
Query:  112 GVKKVPLHLQSSQNRLCIKGAKIVNDDRMFDADVYIEDGIIKQLGTNLVIPGGVRCVEANGKLLIPGGIDTHTHMEFPFMGTVSSDDFYSGTRAALAGGTTMIIDFVIGQKGTSLIDSYNQYREKADSKVCCDYGLHVIVSSYNESVGNEMEKLASEHGINSFKIFMAYKDSLMLEDDEMYEVFKKCKSIGALAQVHAENGKLIEKKSLELISKGITGPEGHLYSRPEEVECEATNRAIMLADQANCPLYVVHVMSKGAADIISDARRQGKVVFGEPIAAGLGTDGSHYSHSCWRHAAGYVMSPPLRNDRNTSKHLMQLLASGDLECTGTDHCVFKASQKALGKDDFRSIPNGVNGVEDRMSVIWEKGVVTGILDPCKFVAVTSTNAAKIFNIYPKKGRIDIGSDADLVLWNPDVRRTISASTHYQNVDFNIFEGMHCHGVAEMVISGGKVVLEDGNLRVAQGTGKFVPTNPFCNYVFNKVKLRDQCHKTLANKVERQPYDGPVEDLSKEMTNLNMNFDDDTDSQQNAISSEFVNTKRPLTSGGGRHMQDSSFALSGAQIDDNLPTRSGIRTRQPPGGTA--TSL 1860
            G K +P   + + +RL IKGAKIVNDD+ F AD+Y+EDG+IKQ+G NL++PGGV+ ++A+G++++PGGID HT  + P  G  ++DDFY GTRAALAGGTTMIID V+ + G  LI ++NQ+RE ADSK CCDY LHV ++ +++ +  EME L  +HG+NSF +++AYKD   L D ++YEVF   + +GA+AQVHAENG +I ++   ++  GITGPEGH+ SRPEEVE EA NR++ +A+Q NCPLY+  VMSK A+D+I+ AR++G VV+GEPI A +GTDGSHY    W  AA YV SPPL  D  T  +L  LL+ GDL+  G+ HC F  +Q+A+GKDDF  IP G NG E+RMS+IW+K VVTG +D  +FVAVTSTNAAKIFN+YP+KGRI +GSDADLVLW+PDV + ISA +H   V++NIFEGM   G   +VIS GK+VLE+G L   +G+G++VP  PF +YV+ ++K R +  +     V R  YDGPV ++S     +            +A +S      +P+     R++  S F+LSGAQ+DDN+P R+  R   PPGG A  TSL
Sbjct:    6 GKKNIP---RITSDRLLIKGAKIVNDDQSFSADIYMEDGLIKQIGENLIVPGGVKTIDAHGQMVMPGGIDVHTRFQMPDRGMTAADDFYQGTRAALAGGTTMIIDHVVAEPGVGLIAAFNQWREWADSKSCCDYSLHVDITEWHKGIQEEMETLVKDHGVNSFLVYLAYKDVFQLTDSQIYEVFSGIRDLGAIAQVHAENGDIIAEEQRRILELGITGPEGHVLSRPEEVEAEAVNRSVTVANQTNCPLYITKVMSKSASDVIAQARKKGTVVYGEPITASVGTDGSHYWSKNWGKAAAYVTSPPLSPDPTTPDYLNSLLSCGDLQVVGSGHCTFNTAQRAVGKDDFTLIPEGTNGAEERMSIIWDKCVVTGKMDENQFVAVTSTNAAKIFNLYPRKGRIAVGSDADLVLWDPDVTKIISAKSHNSAVEYNIFEGMEVRGAPLVVISQGKIVLEEGTLHTTEGSGRYVPRKPFPDYVYKRIKARSRLAEL--RGVPRGLYDGPVCEVSVTPKAVT--------PASSAKTSPAKQASQPV-----RNLHQSGFSLSGAQVDDNIPRRNTQRIVAPPGGRANITSL 572          
BLAST of Dihydropyrimidinase vs. Ensembl Cavefish
Match: dpysl2b (dihydropyrimidinase-related protein 2 [Source:NCBI gene;Acc:103036518])

HSP 1 Score: 637.106 bits (1642), Expect = 0.000e+0
Identity = 301/583 (51.63%), Postives = 410/583 (70.33%), Query Frame = 1
Query:  118 KKVPLHLQSSQNRLCIKGAKIVNDDRMFDADVYIEDGIIKQLGTNLVIPGGVRCVEANGKLLIPGGIDTHTHMEFPFMGTVSSDDFYSGTRAALAGGTTMIIDFVIGQKGTSLIDSYNQYREKADSKVCCDYGLHVIVSSYNESVGNEMEKLASEHGINSFKIFMAYKDSLMLEDDEMYEVFKKCKSIGALAQVHAENGKLIEKKSLELISKGITGPEGHLYSRPEEVECEATNRAIMLADQANCPLYVVHVMSKGAADIISDARRQGKVVFGEPIAAGLGTDGSHYSHSCWRHAAGYVMSPPLRNDRNTSKHLMQLLASGDLECTGTDHCVFKASQKALGKDDFRSIPNGVNGVEDRMSVIWEKGVVTGILDPCKFVAVTSTNAAKIFNIYPKKGRIDIGSDADLVLWNPDVRRTISASTHYQNVDFNIFEGMHCHGVAEMVISGGKVVLEDGNLRVAQGTGKFVPTNPFCNYVFNKVKLRDQCHKTLANKVERQPYDGPVEDLSKEMTNLNMNFDDDTDSQQNAISSEFVNTKRPLTSGGGRHMQDSSFALSGAQIDDNLPTRSGIRTRQPPGGTA--TSL 1860
            K++  ++  + +RL IKGAKIVNDD+ F AD+Y+EDG+IKQ+G NL++PGGV+ ++A+G++++PGGID HT  + P  G  ++DDFY GTRAALAGGTTMIID V+ + G  LI ++NQ+RE ADSK CCDY LHV ++ +++ +  EME L  +HG+NSF +++AYKD   L D ++YEVF   + +GA+AQVHAENG +I ++   ++  GITGPEGH+ SRPEEVE EA NR++ +A+Q NCPLY+  VMSK A+D+I+ AR++G VV+GEPI A +GTDGSHY    W  AA YV SPPL  D  T  +L  LL+ GDL+  G+ HC F  +Q+A+GKDDF  IP G NG E+RMS+IW+K VVTG +D  +FVAVTSTNAAKIFN+YP+KGRI +GSDADLVLW+PDV + ISA +H   V++NIFEGM   G   +VIS GK+VLE+G L   +G+G++VP  PF +YV+ ++K R +  +     V R  YDGPV ++S     +            +A +S      +P+     R++  S F+LSGAQ+DDN+P R+  R   PPGG A  TSL
Sbjct:   59 KELLQNINDTSDRLLIKGAKIVNDDQSFSADIYMEDGLIKQIGENLIVPGGVKTIDAHGQMVMPGGIDVHTRFQMPDRGMTAADDFYQGTRAALAGGTTMIIDHVVAEPGVGLIAAFNQWREWADSKSCCDYSLHVDITEWHKGIQEEMETLVKDHGVNSFLVYLAYKDVFQLTDSQIYEVFSGIRDLGAIAQVHAENGDIIAEEQRRILELGITGPEGHVLSRPEEVEAEAVNRSVTVANQTNCPLYITKVMSKSASDVIAQARKKGTVVYGEPITASVGTDGSHYWSKNWGKAAAYVTSPPLSPDPTTPDYLNSLLSCGDLQVVGSGHCTFNTAQRAVGKDDFTLIPEGTNGAEERMSIIWDKCVVTGKMDENQFVAVTSTNAAKIFNLYPRKGRIAVGSDADLVLWDPDVTKIISAKSHNSAVEYNIFEGMEVRGAPLVVISQGKIVLEEGTLHTTEGSGRYVPRKPFPDYVYKRIKARSRLAEL--RGVPRGLYDGPVCEVSVTPKAVT--------PASSAKTSPAKQASQPV-----RNLHQSGFSLSGAQVDDNIPRRNTQRIVAPPGGRANITSL 626          
BLAST of Dihydropyrimidinase vs. Ensembl Cavefish
Match: dpys (dihydropyrimidinase [Source:ZFIN;Acc:ZDB-GENE-070508-1])

HSP 1 Score: 620.157 bits (1598), Expect = 0.000e+0
Identity = 292/480 (60.83%), Postives = 364/480 (75.83%), Query Frame = 1
Query:  142 SSQNRLCIKGAKIVNDDRMFDADVYIEDGIIKQLGTNLVIPGGVRCVEANGKLLIPGGIDTHTHMEFPFMGTVSSDDFYSGTRAALAGGTTMIIDFVIGQKGTSLIDSYNQYREKADSKVCCDYGLHVIVSSYNESVGNEMEKLASEHGINSFKIFMAYKDSLMLEDDEMYEVFKKCKSIGALAQVHAENGKLIEKKSLELISKGITGPEGHLYSRPEEVECEATNRAIMLADQANCPLYVVHVMSKGAADIISDARRQGKVVFGEPIAAGLGTDGSHYSHSCWRHAAGYVMSPPLRNDRNTSKHLMQLLASGDLECTGTDHCVFKASQKALGKDDFRSIPNGVNGVEDRMSVIWEKGVVTGILDPCKFVAVTSTNAAKIFNIYPKKGRIDIGSDADLVLWNPD----VRRTISASTHYQNVDFNIFEGMHCHGVAEMVISGGKVVLEDGNLRVAQGTGKFVPTNPFCNYVFNKVKLRDQ 1569
            + ++R+ IKG K+VN++    ADVY+EDGII+ +G +L  P G R ++A G L++PGGIDTHTHME  FMGTV+ DDFY+GT+AA+AGGTTMI+DFVI QKG SL+++Y ++R  AD KVCCDY LHV V+ ++ESV  EME L  E G+NSFK+F+AYK+  ML D E+Y  F  CK IGA+AQVHAENG LI + + +++S GITGPEGH   RPEEVE EAT RAI +A   NCPLYVVHVMSK AA +++ ARR G+VVFGEPIAAGLGTDG+HY +  W HAAG+VM PPLR D +T  +LM LLA+ DL  TGTD+C F   QKALGKDDF  IPNGVNGVEDRMSVIWEKGV +G +D  +FVAVTS+NAAK+FN+YP+KGRI  GSDADLV+W P       R ISA TH+Q VD+NIFEGM CHGV  + IS G+VV E G +    GTG+F+P  P   +V+ ++K R++
Sbjct:    2 AHKSRILIKGGKVVNEECSERADVYVEDGIIQAVGLDLQTPAGTRVIDARGNLILPGGIDTHTHMELAFMGTVAVDDFYTGTKAAVAGGTTMILDFVIPQKGASLLEAYERWRNTADRKVCCDYSLHVAVTWWDESVKREMETLVQEKGVNSFKMFLAYKNVFMLSDHELYSAFSHCKDIGAIAQVHAENGDLIAEGAKKMLSLGITGPEGHELCRPEEVEAEATQRAITIAHSVNCPLYVVHVMSKSAAKVVASARRNGRVVFGEPIAAGLGTDGTHYWNKDWAHAAGFVMGPPLRPDPSTPGYLMDLLANDDLSVTGTDNCTFSVCQKALGKDDFTKIPNGVNGVEDRMSVIWEKGVHSGKMDENRFVAVTSSNAAKLFNLYPQKGRIAKGSDADLVIWGPKSCCVCFRVISAKTHHQAVDYNIFEGMVCHGVPLVTISRGRVVYEHGRVVAEPGTGRFIPRKPCAEFVYKRIKQREE 481          
BLAST of Dihydropyrimidinase vs. Ensembl Cavefish
Match: DPYSL2 (dihydropyrimidinase like 2 [Source:HGNC Symbol;Acc:HGNC:3014])

HSP 1 Score: 608.601 bits (1568), Expect = 0.000e+0
Identity = 280/508 (55.12%), Postives = 374/508 (73.62%), Query Frame = 1
Query:  112 GVKKVPLHLQSSQNRLCIKGAKIVNDDRMFDADVYIEDGIIKQLGTNLVIPGGVRCVEANGKLLIPGGIDTHTHMEFPFMGTVSSDDFYSGTRAALAGGTTMIIDFVIGQKGTSLIDSYNQYREKADSKVCCDYGLHVIVSSYNESVGNEMEKLASEHGINSFKIFMAYKDSLMLEDDEMYEVFKKCKSIGALAQVHAENGKLIEKKSLELISKGITGPEGHLYSRPEEVECEATNRAIMLADQANCPLYVVHVMSKGAADIISDARRQGKVVFGEPIAAGLGTDGSHYSHSCWRHAAGYVMSPPLRNDRNTSKHLMQLLASGDLECTGTDHCVFKASQKALGKDDFRSIPNGVNGVEDRMSVIWEKGVVTGILDPCKFVAVTSTNAAKIFNIYPKKGRIDIGSDADLVLWNPDVRRTISASTHYQNVDFNIFEGMHCHGVAEMVISGGKVVLEDGNLRVAQGTGKFVPTNPFCNYVFNKVKLRDQCHKTLANKVERQPYDGPVEDLS 1635
            G K +P   + + +RL IKG KIVNDD+ F AD+Y+EDG+IKQ+G NL++PGGV+ ++A+G++LIPGGID HT  + P  G  ++DDFY GTRAALAGGTTMIID V+ + G SLI ++NQ+RE ADSK CCDY LHV ++ ++  +  EME L  +HG+NSF +++AYKD   L D +MYEVF   + +GA+AQVHAENG +I ++   ++  GITGPEGH+ SRPEEVE EA NRA+ +A+Q NCPLYV  VMSK AAD+I+ AR++G VV+GEPI A LGTDG+HY    W  AA YV SPPL  D  T  +L  LL+ GDL+ TG+ HC F  SQ+A+GKD+F  IP G NG E+RMS++W+K VV+G +D  +FVAVTSTNAAK+FN+YP+KGRI +GSDADLVLW+PDV + ISA +H   V++NIFEG+   G   +VIS GK+VLEDGNL   +G+G+++   PF +YV+ ++K R +  +     V R  YDGPV +++
Sbjct:    6 GKKNIP---RITSDRLLIKGGKIVNDDQSFHADIYMEDGVIKQIGENLIVPGGVKTIDAHGRMLIPGGIDVHTRFQMPDRGMTAADDFYQGTRAALAGGTTMIIDHVVPEPGVSLISAFNQWREWADSKSCCDYSLHVDLTEWHGGIQEEMETLVKDHGVNSFLVYLAYKDVFQLNDSQMYEVFSVIRDLGAIAQVHAENGDIIAEEQKRILDLGITGPEGHVLSRPEEVEAEAVNRAVTVANQTNCPLYVTKVMSKSAADVIAQARKKGTVVYGEPITASLGTDGTHYWSKNWAKAAAYVTSPPLSPDPTTPDYLNSLLSCGDLQITGSSHCTFNTSQRAVGKDNFTLIPEGTNGTEERMSIVWDKCVVSGKMDENQFVAVTSTNAAKVFNLYPRKGRIAVGSDADLVLWDPDVTKIISAKSHNLAVEYNIFEGVEVRGSPLVVISQGKIVLEDGNLHTTEGSGRYITRKPFPDYVYKRIKARSRLAEL--RGVPRGLYDGPVCEVT 508          
BLAST of Dihydropyrimidinase vs. Ensembl Cavefish
Match: dpysl4 (dihydropyrimidinase like 4 [Source:NCBI gene;Acc:103040013])

HSP 1 Score: 602.823 bits (1553), Expect = 0.000e+0
Identity = 289/578 (50.00%), Postives = 394/578 (68.17%), Query Frame = 1
Query:  112 GVKKVPLHLQSSQNRLCIKGAKIVNDDRMFDADVYIEDGIIKQLGTNLVIPGGVRCVEANGKLLIPGGIDTHTHMEFPFMGTVSSDDFYSGTRAALAGGTTMIIDFVIGQKGTSLIDSYNQYREKADSKVCCDYGLHVIVSSYNESVGNEMEKLASEHGINSFKIFMAYKDSLMLEDDEMYEVFKKCKSIGALAQVHAENGKLIEKKSLELISKGITGPEGHLYSRPEEVECEATNRAIMLADQANCPLYVVHVMSKGAADIISDARRQGKVVFGEPIAAGLGTDGSHYSHSCWRHAAGYVMSPPLRNDRNTSKHLMQLLASGDLECTGTDHCVFKASQKALGKDDFRSIPNGVNGVEDRMSVIWEKGVVTGILDPCKFVAVTSTNAAKIFNIYPKKGRIDIGSDADLVLWNPDVRRTISASTHYQNVDFNIFEGMHCHGVAEMVISGGKVVLEDGNLRVAQGTGKFVPTNPFCNYVFNKVKLRDQCHKTLANKVERQPYDGPVEDLSKEMTNLNMNFDDDTDSQQNAISSEFVNTKRPLTSGGGRHMQDSSFALSGAQIDDNLPTRSGIRTRQPPGG 1845
            G K +P   + + ++L IKG KIVNDD+ F AD++IEDG IKQ+G NL++P GV+ V+A G ++IPGGID +T ++   MG   +DDFY GTRAALAGGTTMIID V+ + G SL+ +++Q+R+ AD + CCDY LH+ ++ ++E +  E+E L  + G+NSF +FM+YKD     D +MYE+F   + +GA+AQVHAENG +I+++   L+  GITGPEGH+ S PEEVE EA  RAI +A QANCPLY+  VMS+ AAD+I+ AR++G V++GEPIAA LGTDGSHY    W  AA +VMSPPL  D  T  +L  +L+ GDL+ T + HC F  +QKA+GKD+F  IP G NG+E+RMS++W+K V +G +D  +FVAVTSTNAAKIFN+YP+KGRI +GSDADLV+WN    +T SA++H   V+ NIFE M C G   +VIS G++VLEDG L   +G+G+FVP   F +YV+ ++K R +  +  A  V R  YDGPV D+      ++M             SS   NT  P      R++  S F LSG Q+DD++P R+  R   PPGG
Sbjct:    5 GKKSIP---RLTGDKLIIKGGKIVNDDQSFYADIFIEDGTIKQIGENLIVPSGVKTVDAYGHIVIPGGIDVNTSLQAQHMGMSPADDFYHGTRAALAGGTTMIIDHVVPEPGASLLAAFDQWRDVADKRSCCDYSLHIDITRWHEGMFEELETLVKDQGVNSFLVFMSYKDRFQSSDSQMYEIFGILRDLGAIAQVHAENGDIIDEEQKRLLDMGITGPEGHVLSHPEEVETEAVYRAITIAKQANCPLYITKVMSRPAADVIAKARKKGMVIYGEPIAASLGTDGSHYWSQNWAKAAAFVMSPPLSPDPATPDYLNSMLSCGDLQVTASAHCTFSTAQKAVGKDNFTLIPEGTNGIEERMSIVWDKAVASGKMDENEFVAVTSTNAAKIFNLYPRKGRIAVGSDADLVIWNTKETKTFSATSHNLTVEMNIFEDMECRGFPVVVISQGRIVLEDGKLDAMEGSGRFVPRKAFPDYVYKRIKARSRMAE--ARGVPRGNYDGPVHDV------ISMTKSVPPTPTTRGPSSSGKNTPGP-----ARNLHQSGFTLSGTQMDDHIPRRTAQRIVAPPGG 566          
BLAST of Dihydropyrimidinase vs. Ensembl Sea Lamprey
Match: dpysl3 (dihydropyrimidinase like 3 [Source:NCBI gene;Acc:553166])

HSP 1 Score: 498.434 bits (1282), Expect = 6.491e-172
Identity = 241/476 (50.63%), Postives = 316/476 (66.39%), Query Frame = 1
Query:  418 IIDFVIGQKGTSLIDSYNQYREKADSKVCCDYGLHVIVSSYNESVGNEMEKLASEHGINSFKIFMAYKDSLMLEDDEMYEVFKKCKSIGALAQVHAENGKLIEKKSLELISKGITGPEGHLYSRPEEVECEATNRAIMLADQANCPLYVVHVMSKGAADIISDARRQGKVVFGEPIAAGLGTDGSHYSHSCWRHAAGYVMSPPLRNDRNTSKHLMQLLASGDLECTGTDHCVFKASQKALGKDDFRSIPNGVNGVEDRMSVIWEKGVVTGILDPCKFVAVTSTNAAKIFNIYPKKGRIDIGSDADLVLWNPDVRRTISASTHYQNVDFNIFEGMHCHGVAEMVISGGKVVLEDGNLRVAQGTGKFVPTNPFCNYVFNKVKLRDQCHKTLANKVERQPYDGPVEDLSKEMTNLNMNFDDDTDSQQNAISSEFVNTKRPLTSGGGRHMQDSSFALSGAQIDDNLPTRSGIRTRQPPGG 1845
            ++D  I + G  L+ + + +RE AD+KVCCDY LHV V  ++E V  E+E L  + GINSF ++MAYKD   + D EMYEVF   + IGA+A VHAENG +I ++   ++  GI GPEGH+ SR EEVE EA NRAI +A+  NCPLY+  VMSK AAD+IS AR++G VV+GEPI A LGTDGSHY    W  AA +V SPPL  D  T  +L  LL+ GDL+ TG+ HC F  +QKALGKD+F  IP G NG+E+RMS++W+K V TG +D  +FVAVTSTNAAKIF++YP+KGRI +GSDADLV+W PD   TISA TH   V++NIFEGM   G   +VIS G++VLE+G L   QG G+FVP   F   V+ ++K R++  +     V R  YDGPV +LS   +++       T S + + +     +  PL     R++  S F+LSGAQ+DD LP R+G R   PPGG
Sbjct:    1 LVDHAIPEPGQGLVAALDAWREWADAKVCCDYSLHVAVPQWHEGVAEELEILVKDRGINSFLVYMAYKDQYQMSDTEMYEVFTFLRDIGAIAMVHAENGDIIAEEQKRILEMGIAGPEGHVLSRAEEVEAEAVNRAISIANHTNCPLYITKVMSKSAADVISQARKKGAVVYGEPITASLGTDGSHYWSKNWAKAAAFVTSPPLSPDPTTPDYLNSLLSCGDLQVTGSAHCTFTTAQKALGKDNFTLIPEGTNGIEERMSIVWDKAVATGKMDENQFVAVTSTNAAKIFSLYPRKGRIAVGSDADLVIWEPDTITTISAKTHTAAVEYNIFEGMEVRGAPLVVISQGRIVLEEGKLSATQGAGRFVPRKAFPEQVYKRIKARNKLAEM--RGVPRGLYDGPVFELSS--SSVRSTTATPTPSARTSPAKSAAQSA-PL-----RNLHQSGFSLSGAQVDDELPRRTGHRIVAPPGG 466          
BLAST of Dihydropyrimidinase vs. Ensembl Sea Lamprey
Match: dpysl2b (dihydropyrimidinase like 2b [Source:ZFIN;Acc:ZDB-GENE-031105-1])

HSP 1 Score: 325.865 bits (834), Expect = 8.303e-108
Identity = 143/256 (55.86%), Postives = 196/256 (76.56%), Query Frame = 1
Query:  151 NRLCIKGAKIVNDDRMFDADVYIEDGIIKQLGTNLVIPGGVRCVEANGKLLIPGGIDTHTHMEFPFMGTVSSDDFYSGTRAALAGGTTMIIDFVIGQKGTSLIDSYNQYREKADSKVCCDYGLHVIVSSYNESVGNEMEKLASEHGINSFKIFMAYKDSLMLEDDEMYEVFKKCKSIGALAQVHAENGKLIEKKSLELISKGITGPEGHLYSRPEEVECEATNRAIMLADQANCPLYVVHVMSKGAADIISDARRQ 918
            +RL IKG +I+NDD+ F AD+Y+EDG IKQ+G NL++PGGV+ +EANG++++PGGID HTH++ P++GT + DDFY GTRAALAGGTTMIID VI + G SL+ +Y Q+RE AD+K CCDY LHV ++ +N  + +EME L  + G+NSF ++MAYKD   L D E+YE F   + +GA+A VHAENG +I ++   ++   ITGPEGH+ SRPEEVE EA NRAI + +Q NCPLY+  VMS+ AAD+I+ +R++
Sbjct:    1 DRLLIKGGRIINDDQSFTADIYVEDGFIKQIGDNLIVPGGVKSIEANGRMVMPGGIDVHTHLQMPYLGTSTMDDFYQGTRAALAGGTTMIIDHVIPEPGCSLLGAYEQWREWADAKACCDYSLHVQLTYWNSELCSEMETLIKDKGVNSFLVYMAYKDKYQLTDAEIYEAFTAIRDLGAIALVHAENGSIIAEEQKRILGLQITGPEGHVLSRPEEVEAEAVNRAITIGNQTNCPLYITKVMSRSAADVIALSRKK 256          
BLAST of Dihydropyrimidinase vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006054.1 (pep scaffold:Pmarinus_7.0:GL477305:540:7425:1 gene:ENSPMAG00000005460.1 transcript:ENSPMAT00000006054.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 262.692 bits (670), Expect = 1.600e-83
Identity = 128/257 (49.81%), Postives = 166/257 (64.59%), Query Frame = 1
Query: 1075 SGDLECTGTDHCVFKASQKALGKDDFRSIPNGVNGVEDRMSVIWEKGVVTGILDPCKFVAVTSTNAAKIFNIYPKKGRIDIGSDADLVLWNPDVRRTISASTHYQNVDFNIFEGMHCHGVAEMVISGGKVVLEDGNLRVAQGTGKFVPTNPFCNYVFNKVKLRDQCHKTLANKVERQPYDGPVEDLSKEMTNLNMNFDDDTDSQQNAISSEFVNTKRPLTSGGGRHMQDSSFALSGAQIDDNLPTRSGIRTRQPPGG 1845
            SGDL  TG+ HC F  +QKALGKDDF  IP G NG+E+RMS++W+KGV TG +D  +FVAVTSTNAAK+FN+YP+KGRI +GSDADL++W+PDV +TISA TH+Q V++NIFEGM   GV   VIS GK+V+EDG L   QG G+FVP   F   V+ ++K R Q   T    V R  YDGPV++++             T   +   ++              R++  S F LSGAQ+DDN+P R+G R   PPGG
Sbjct:    1 SGDLHVTGSAHCTFSTAQKALGKDDFTLIPEGTNGIEERMSIVWDKGVATGKMDENQFVAVTSTNAAKVFNLYPRKGRIAVGSDADLIIWDPDVVKTISAKTHHQAVEYNIFEGMEVRGVPLAVISQGKIVMEDGTLHAMQGVGRFVPRKAFPEQVYKRIKARSQL--TELQGVPRGLYDGPVQEVTVSSRTATPAASAKTSPTRQTAAAAAAQASNL------RNLHQSGFCLSGAQVDDNMPRRTGHRIVAPPGG 249          
BLAST of Dihydropyrimidinase vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004226.1 (pep scaffold:Pmarinus_7.0:GL477658:179183:185371:1 gene:ENSPMAG00000003860.1 transcript:ENSPMAT00000004226.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 48.1358 bits (113), Expect = 4.157e-6
Identity = 36/136 (26.47%), Postives = 60/136 (44.12%), Query Frame = 1
Query:  304 IPGGIDTHTHMEFPFMGTVSSDDFYSGTRAALAGGTTMIIDFVIGQKGTSLIDSYNQYREKADSKVCCDYGLHVIVSSYNESVGNEMEKLASEHGINSFKIFMAYKDSLMLEDDEMYEVFKKCKSIGALAQVHAEN 711
            +PG +D H H+  P  G    +DF SGT AALAGG T++          + +DS    ++ A +   CDY L    S  N +   ++    +   +   + + A +   M    + +E + + + I     VHAE 
Sbjct:   27 LPGLMDVHVHLREP--GGEHKEDFCSGTAAALAGGVTLVCAMPNTNPAVTDLDSLAVVQKAARAGARCDYALFAGASVENAASVRDLSGATAGLKMYLNETYSALRLDNMAHWMQHFESWPRDRVIA----VHAER 156          
BLAST of Dihydropyrimidinase vs. Ensembl Yeast
Match: DAL1 (Allantoinase; converts allantoin to allantoate in the first step of allantoin degradation; expression sensitive to nitrogen catabolite repression [Source:SGD;Acc:S000001466])

HSP 1 Score: 97.4413 bits (241), Expect = 5.724e-22
Identity = 103/412 (25.00%), Postives = 173/412 (41.99%), Query Frame = 1
Query:  301 LIPGGIDTHTHMEFPFMGTVSSDDFYSGTRAALAGGTTMIIDFVIGQ-KGTSLIDSYNQYREKADSKVCCDYGLHVIVSSYNESVGNEMEKLAS--EHGINSFKIFM---AYKDSLMLEDDEMYEVFKKCKSIGALAQVHAENGKLIEKKSLELISKGITGPEGHLYSRPEEVECEATNRAIMLADQAN---CPLYVVHVMSKGAADIISDARRQGKVVFGEP------IAAGLGTDGSHYSHSCWRHAAGYVMSPPLRNDRNTSKHLMQLLASGDLECTGTDHCVFKASQKALGKDDFRSIPNGVNGVEDRMSVIWEKGVVTGILDPCKFVAVTS---TNAAKIFNIYPKKGRIDIGSDADLVLWNPDVRRTISASTHYQNVDFNIFEGMHCHGVAEMVISGGKVVLEDGN 1482
            ++PG +D+H H+  P  G  S + F +GT+AA++GG T ++D  +     T+ ++++    E A+ ++ CD G       +   V + +  L    + G+  FK F+     ++   +  + + E  K       +   HAE  K  E +  +   +        L SRP+  E +A N  +      N    P+++VH+ S  A  +I  AR  G  V  E       IAA    DG+ Y   C          PP+R++ N  + L   L  G +    +DH       K L K DF     G+  V   + +++ +G        C  V + +    N +    +  +KG I  G DADLV+++   +  IS S+ Y       + GM   G     I  G+VV  + N
Sbjct:   62 ILPGLVDSHVHLNEP--GRTSWEGFETGTQAAISGGVTTVVDMPLNAIPPTTNVENFRIKLEAAEGQMWCDVGF------WGGLVPHNLPDLIPLVKAGVRGFKGFLLDSGVEEFPPIGKEYIEEALKVLAEEDTMMMFHAELPKAHEDQ--QQPEQSHREYSSFLSSRPDSFEIDAINLILECLRARNGPVPPVHIVHLASMKAIPLIRKARASGLPVTTETCFHYLCIAAEQIPDGATYFKCC----------PPIRSESN-RQGLWDALREGVIGSVVSDHSPCTPELKNLQKGDFFDSWGGIASVGLGLPLMFTQG--------CSLVDIVTWCCKNTSHQVGLSHQKGTIAPGYDADLVVFDTASKHKISNSSVYFKNKLTAYNGMTVKGTVLKTILRGQVVYTNAN 444          
BLAST of Dihydropyrimidinase vs. Ensembl Nematostella
Match: EDO46551 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RPQ7])

HSP 1 Score: 700.664 bits (1807), Expect = 0.000e+0
Identity = 333/571 (58.32%), Postives = 422/571 (73.91%), Query Frame = 1
Query:  142 SSQNRLCIKGAKIVNDDRMFDADVYIEDGIIKQLGTNLVIPGGVRCVEANGKLLIPGGIDTHTHMEFPFMGTVSSDDFYSGTRAALAGGTTMIIDFVIGQKGTSLIDSYNQYREKADSKVCCDYGLHVIVSSYNESVGNEMEKLASEHGINSFKIFMAYKDSLMLEDDEMYEVFKKCKSIGALAQVHAENGKLIEKKSLELISKGITGPEGHLYSRPEEVECEATNRAIMLADQANCPLYVVHVMSKGAADIISDARRQGKVVFGEPIAAGLGTDGSHYSHSCWRHAAGYVMSPPLRNDRNTSKHLMQLLASGDLECTGTDHCVFKASQKALGKDDFRSIPNGVNGVEDRMSVIWEKGVVTGILDPCKFVAVTSTNAAKIFNIYPKKGRIDIGSDADLVLWNPDVRRTISASTHYQNVDFNIFEGMHCHGVAEMVISGGKVVLEDGNLRVAQGTGKFVPTNPFCNYVFNKVKLRDQCHKTLANKVERQPYDGPVEDLSKEMTNLNMNFDDDTDSQQNAISSEFVNTKRPLTSGGGRHMQDSSFALSGAQIDDNLPTRSGIRTRQPPGGTAT 1854
            + ++R+ IKG  IVNDD+MF+ADVYIE+G+IK++  +++ PGG + ++A+ KL++PGGIDTHTH++ PFMGT + DDF+ GT+AALAGGTTMIIDFVI  KG SL+++Y+++R  AD KVCCDYG HV V+ ++E V  EME L  E GINSFK FMAYKD +M+ D EM   +KKCK IGA+AQVHAENG LI++ + ++I+ GITGPEGH   RPEEVE EAT RAI +A+Q +CPLYVVHVMSK +A +ISDARR GKVV GEPIAAGLG DG++Y H CWRH AG+VM PPLR D +T +HLM LLA+ DL+CTGTD+C F + QKALGK+DFR IPNGVNG+EDRMSVIWEKGV  G +DPC+FVAVTST AAKIFN+YP+KGRI +GSDAD+V+W+P+  R ISA TH+Q VDFNIFEGM CHGV  + IS GKVV E G   V +G+G+F+PT PF +Y+++++  RD+       KV+R+PY G V  L+ E       F   T   Q  +       K P      R +  S F LSG Q DD  P R   R  +PPGG ++
Sbjct:    6 AQKDRILIKGGTIVNDDQMFEADVYIENGLIKEISKSVICPGGTKVIDASRKLILPGGIDTHTHLQMPFMGTTAIDDFFIGTKAALAGGTTMIIDFVIPAKGESLLEAYDKWRGWADEKVCCDYGFHVAVTWWSEEVAEEMEILVKEKGINSFKTFMAYKDVMMINDAEMINCYKKCKEIGAIAQVHAENGDLIDESAKKMIAMGITGPEGHEMCRPEEVEAEATQRAITIANQVSCPLYVVHVMSKSSAKVISDARRLGKVVIGEPIAAGLGCDGTNYWHKCWRHGAGHVMGPPLRPDTSTPEHLMNLLANDDLQCTGTDNCTFSSEQKALGKNDFRKIPNGVNGIEDRMSVIWEKGVHAGKMDPCRFVAVTSTTAAKIFNVYPQKGRIAVGSDADIVVWDPEATRVISAKTHHQAVDFNIFEGMECHGVPVVTISQGKVVYEGGEFHVVRGSGRFIPTPPFSHYMYSRIHTRDK--NCQPKKVDREPYTGKV--LTIEPDPKAAVF---TSPAQRRMKEREEVKKNP-----HRDLHRSGFELSGRQFDDERPYRPSSRVAKPPGGASS 564          
BLAST of Dihydropyrimidinase vs. Ensembl Nematostella
Match: EDO49158 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RH45])

HSP 1 Score: 106.301 bits (264), Expect = 1.062e-24
Identity = 99/415 (23.86%), Postives = 168/415 (40.48%), Query Frame = 1
Query:  304 IPGGIDTHTHMEFPFMGTVSSDDFYSGTRAALAGGTTMIIDFVIGQ-KGTSLIDSYNQYREKADSKVCCDYGLHVIVSSYNESVGNEMEKLASEHGINSFKIFMAY---KDSLMLEDDEMYEVFKKCKSIGALAQVHAENGKLIEKKSLELISKGITGP-------EGHLYSRPEEVECEATNRAIMLADQANCPLYVVHVMSKGAADIISDARRQGKVVFGEPIAAGLGTDGSHYSHSCWRHAAGYVMSPPLRNDRNTSKHLMQLLASGDLECTGTDHCVFKASQKALGKDDFRSIPNGVNGVEDRMSVIWEKGVVTGILDPCKFVAVTSTNAAKIFNIYPKKGRIDIGSDADLVLWNPDVRRTISASTHYQNVDFNIFEGMHCHGVAEMVISGGKVVLEDGNLRVAQGTGKFV 1515
            +PG +D+H H+  P  G    + F + T+AA +GG T ++D  +     T+ +       + A  K   D      V   N+    +M ++    G+  FK F+ +   ++   + +  +    +K +  G++   HAE            + +GI  P       +  L +RPE +E +A    I L D    P ++VH+ S  A D I  AR  G  +  E     L              A  Y   PP+R DR+  + L   +   D++   +DH       K L + DF     G++ ++  +S+ W      G L     V V     +K+ ++  +KG I +G DAD V+W+P+    + +S          + G    G     I  G+VV   GN    +  G F+
Sbjct:    1 MPGVVDSHVHINQP--GRTQWEGFETATQAAASGGITTLVDMPLNSIPPTTTVQGLKAKMQSAQGKCWVDVAFWGGVIPGNQDELQDMIRM----GVRGFKCFLIHSGVEEFPHVSEAGVCTALEKMRGFGSVLLFHAE------------VDEGIPVPKDDKQKYDTFLKTRPESMENKAIEMVIHLCDHYRVPCHIVHLSSGSALDSIRSARSSGIPLTVETTHHYLSLTAEEVPDG----ATQYKCCPPIR-DRSNQEVLWNAVKFRDIDLVVSDHSPCTPDLKLLDQGDFIGAWGGISSLQYGLSLFWSGARCRG-LGLHDVVRVLCEQPSKLCSLQHRKGMISVGKDADFVIWDPNEEFMVKSSDIRHRNKVTPYAGKKLFGRVHQTILRGQVVFS-GNTVHEEPLGDFL 390          
BLAST of Dihydropyrimidinase vs. Ensembl Nematostella
Match: EDO25804 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A8DVF6])

HSP 1 Score: 66.2402 bits (160), Expect = 1.210e-11
Identity = 69/245 (28.16%), Postives = 109/245 (44.49%), Query Frame = 1
Query:  157 LCIKGAKIVNDDRMFDADVYIEDGIIKQLGTNLVIPGGVRCV--EANGKLLIPGGIDTHTHMEFPFMGTVSSDDFYSGTRAALAGGTTMIIDFVIGQKGTSLIDSYNQYREKADSKVCCDYGLHVIVSSYNESVGNEMEKLASEHGINSFKIFMAYKDSLMLEDDEMYEVFKKC-KSIGALAQVHAENGKLIE---KKSLELISKGITGPEGHLYSRPEEVECEATNRAIMLADQANCPLYVVHV 873
              I+ AKIVN+  +F+ DV IED  IK++  + + P    CV  +A G  LIPG ID   H   P  G     +  S +RAA+AGG T  I+           +   Q  + A      +Y    ++   N+++   ++   +   +   K+F+      ML D++  EV +K   S   L  VH E+   I+   +K  E     I     HL  R  E    ++++AI LA +    L+V H+
Sbjct:    4 FLIRNAKIVNEGVVFEGDVLIEDEFIKEIA-DKISPKSSECVIIDAEGSYLIPGAIDDQVHFREP--GLTHKGNIASESRAAIAGGITSFIEQPNTVPNAVTQELLEQKYQIAAETSYANYSF--MMGGTNDNLEEVLK--TNPRNVAGIKLFLGSSTGNMLVDNQ--EVLEKIFSSTKMLIAVHCEDEGTIKANLEKYKEEFGDDIPMKYHHLI-RSTEACYLSSSKAIELAKKTGARLHVFHL 238          
BLAST of Dihydropyrimidinase vs. Ensembl Nematostella
Match: EDO29083 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T4N0])

HSP 1 Score: 53.9138 bits (128), Expect = 2.375e-7
Identity = 35/98 (35.71%), Postives = 50/98 (51.02%), Query Frame = 1
Query:  238 QLGTNLVIPGGVRCVEANGKLLIPGGIDTHTHMEFPFMGTVSSDDFYSGTRAALAGGTTMIIDFVIGQKGTSLID--SYNQYREKADSKVCCDYGLHV 525
            +L TN+ I    R V       +PG ID H H+  P  G    +DF SGT AALAGG TM++   +      L+D  S+N  ++   +   CDY L++
Sbjct:  884 KLKTNIDIISTARIVR------LPGLIDVHVHLREP--GATHKEDFASGTAAALAGGITMVL--AMPNTNPPLVDEESFNLAKKLGTAGARCDYALYL 971          
BLAST of Dihydropyrimidinase vs. Ensembl Nematostella
Match: EDO37703 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SF31])

HSP 1 Score: 53.9138 bits (128), Expect = 2.473e-7
Identity = 35/98 (35.71%), Postives = 50/98 (51.02%), Query Frame = 1
Query:  238 QLGTNLVIPGGVRCVEANGKLLIPGGIDTHTHMEFPFMGTVSSDDFYSGTRAALAGGTTMIIDFVIGQKGTSLID--SYNQYREKADSKVCCDYGLHV 525
            +L TN+ I    R V       +PG ID H H+  P  G    +DF SGT AALAGG TM++   +      L+D  S+N  ++   +   CDY L++
Sbjct: 1457 KLKTNIDIISTARIVR------LPGLIDVHVHLREP--GATHKEDFASGTAAALAGGITMVL--AMPNTNPPLVDEESFNLAKKLGTAGARCDYALYL 1544          
BLAST of Dihydropyrimidinase vs. Ensembl Medaka
Match: dpys (dihydropyrimidinase [Source:NCBI gene;Acc:101161186])

HSP 1 Score: 636.721 bits (1641), Expect = 0.000e+0
Identity = 304/494 (61.54%), Postives = 371/494 (75.10%), Query Frame = 1
Query:  151 NRLCIKGAKIVNDDRMFDADVYIEDGIIKQLGTNLVIPGGVRCVEANGKLLIPGGIDTHTHMEFPFMGTVSSDDFYSGTRAALAGGTTMIIDFVIGQKGTSLIDSYNQYREKADSKVCCDYGLHVIVSSYNESVGNEMEKLASEHGINSFKIFMAYKDSLMLEDDEMYEVFKKCKSIGALAQVHAENGKLIEKKSLELISKGITGPEGHLYSRPEEVECEATNRAIMLADQANCPLYVVHVMSKGAADIISDARRQGKVVFGEPIAAGLGTDGSHYSHSCWRHAAGYVMSPPLRNDRNTSKHLMQLLASGDLECTGTDHCVFKASQKALGKDDFRSIPNGVNGVEDRMSVIWEKGVVTGILDPCKFVAVTSTNAAKIFNIYPKKGRIDIGSDADLVLWNPDVRRTISASTHYQNVDFNIFEGMHCHGVAEMVISGGKVVLEDGNLRVAQGTGKFVPTNPFCNYVFNKVKLRDQCHKTLANKVERQPYDGPVEDL 1632
            +R+ IKG K+VN+D    +DVYIE+G I  +G NL +  GVR ++A GKL+IPGGIDTHTHME  FMGT + DDF+ GT+AALAGGTTMI+DFVI QKG SL+++Y+++R+ AD KVCCDY LHV V+ + E V  EME LA E G+NSFK+FMAYKD  ML D E++  F +CK IGA+AQVHAENG LI + + +++S GITGPEGH   RPEEVE EAT RAI +A   NCPLYVVHVMSK AA ++S ARR G+VVFGEPIAAGLGTDG+HY H  W HAAG+VM PPLR D +T  +LM LLA+ DL  TGTD+C F   QKALGKDDF  IPNGVNGVEDRMSVIWEKGV +G +D  +FVAVTS+ AAKIFN+YP+KGRI   SDAD+V+W+P   R ISA TH+Q VD+NIFEGM CHGV  + IS G VV E G L+V+ G G+F+P  P   +V+ ++K RDQ  +  A  V R PY G +  L
Sbjct:    5 SRILIKGGKVVNEDCSVFSDVYIENGKIADVGLNLQVSAGVRVIDATGKLVIPGGIDTHTHMELQFMGTKAVDDFHIGTKAALAGGTTMILDFVIPQKGKSLLEAYDRWRKTADPKVCCDYSLHVAVTWWGEQVKKEMETLAKEKGVNSFKMFMAYKDVFMLSDSELHAAFTQCKDIGAVAQVHAENGDLIAEGAKKMLSLGITGPEGHELCRPEEVEAEATQRAITIAHTVNCPLYVVHVMSKSAAKVVSSARRDGRVVFGEPIAAGLGTDGTHYWHKEWAHAAGFVMGPPLRPDPSTPDYLMDLLANDDLSVTGTDNCTFSVCQKALGKDDFTKIPNGVNGVEDRMSVIWEKGVHSGKMDENRFVAVTSSTAAKIFNLYPQKGRIAKNSDADVVIWDPKSTRIISAKTHHQAVDYNIFEGMKCHGVPAVTISRGIVVYEHGKLQVSPGHGRFIPREPMSEFVYKRIKQRDQVGRPTA--VIRDPYKGSIVSL 496          
BLAST of Dihydropyrimidinase vs. Ensembl Medaka
Match: dpysl2b (dihydropyrimidinase-related protein 2 [Source:NCBI gene;Acc:101155946])

HSP 1 Score: 635.18 bits (1637), Expect = 0.000e+0
Identity = 306/588 (52.04%), Postives = 416/588 (70.75%), Query Frame = 1
Query:  112 GVKKVPLHLQSSQNRLCIKGAKIVNDDRMFDADVYIEDGIIKQLGTNLVIPGGVRCVEANGKLLIPGGIDTHTHMEFPFMGTVSSDDFYSGTRAALAGGTTMIIDFVIGQKGTSLIDSYNQYREKADSKVCCDYGLHVIVSSYNESVGNEMEKLASEHGINSFKIFMAYKDSLMLEDDEMYEVFKKCKSIGALAQVHAENGKLIEKKSLELISKGITGPEGHLYSRPEEVECEATNRAIMLADQANCPLYVVHVMSKGAADIISDARRQGKVVFGEPIAAGLGTDGSHYSHSCWRHAAGYVMSPPLRNDRNTSKHLMQLLASGDLECTGTDHCVFKASQKALGKDDFRSIPNGVNGVEDRMSVIWEKGVVTGILDPCKFVAVTSTNAAKIFNIYPKKGRIDIGSDADLVLWNPDVRRTISASTHYQNVDFNIFEGMHCHGVAEMVISGGKVVLEDGNLRVAQGTGKFVPTNPFCNYVFNKVKLRDQCHKTLANKVERQPYDGPVEDLS---KEMTNLNMNFDDDTDSQQNAISSEFVNTKRPLTSGGGRHMQDSSFALSGAQIDDNLPTRSGIRTRQPPGGTA--TSL 1860
            G K +P   + + +RL I+GAKIVNDD+ F ADVY+EDG+IKQ+G NL++PGGV+ ++A+G++L+PGGID HT  + P  G  ++DDFY GT+AALAGGTTMI+D V+ + G SL+ ++ Q+RE ADSK CCDY LH+ ++ +++ +  EME L  +HG+NSF +++AYKD   L D ++YEVF   + +GA+AQVHAENG ++ ++   ++ +GITGPEGH+ S PEEVE EA NR++ +A+Q NCPLYV  VMSK AAD+I+ AR++G VV+GEPI A LGTDGSHY    W  AA YV SPPL  D  T  +L  LL+ GDL+ TG+ HC F  +Q+A+GKDDF  IP GVNG E+RMS+IW+K VVTG +D  +FVAVTSTNAAKIFN+YP+KGRI +GSDADLVLW+PDV + ISA +H   V++NIFEG    G   +VIS GK++LE+GNL V +G+G+FV   PF +YV+ ++K R +  +     V R  YDGPV ++S   K MT ++           +A +S      +P+     R++  S F+LSGAQ+DDN+P R+  R   PPGG A  TSL
Sbjct:    6 GKKNIP---RITSDRLLIRGAKIVNDDQSFCADVYMEDGVIKQIGENLIVPGGVKTIDAHGRMLMPGGIDVHTRFQMPDRGMTAADDFYQGTKAALAGGTTMILDHVLPEPGVSLLSAFEQWREWADSKACCDYSLHIDITEWHKGIQEEMETLVKDHGVNSFLVYLAYKDIFQLTDAQVYEVFSVIRDLGAIAQVHAENGDIVAEEQRRILEQGITGPEGHVLSHPEEVEAEAVNRSVTVANQTNCPLYVTKVMSKSAADVIAQARKKGTVVYGEPITASLGTDGSHYWSKNWAKAAAYVTSPPLSPDPTTPDYLNSLLSCGDLQVTGSAHCPFNTAQRAVGKDDFTLIPEGVNGTEERMSIIWDKCVVTGKMDENQFVAVTSTNAAKIFNLYPRKGRIAVGSDADLVLWDPDVTKIISAKSHNSTVEYNIFEGTEVRGGPLVVISQGKIILEEGNLHVTEGSGRFVARKPFPDYVYKRIKARSRLAEL--RGVPRGLYDGPVCEVSVTPKTMTPVS-----------SAKTSPAKQPSQPV-----RNLHQSGFSLSGAQVDDNIPRRNTQRIVAPPGGRANITSL 572          
BLAST of Dihydropyrimidinase vs. Ensembl Medaka
Match: dpysl3 (dihydropyrimidinase-related protein 3 [Source:NCBI gene;Acc:101165934])

HSP 1 Score: 619.772 bits (1597), Expect = 0.000e+0
Identity = 293/566 (51.77%), Postives = 391/566 (69.08%), Query Frame = 1
Query:  151 NRLCIKGAKIVNDDRMFDADVYIEDGIIKQLGTNLVIPGGVRCVEANGKLLIPGGIDTHTHMEFPFMGTVSSDDFYSGTRAALAGGTTMIIDFVIGQKGTSLIDSYNQYREKADSKVCCDYGLHVIVSSYNESVGNEMEKLASEHGINSFKIFMAYKDSLMLEDDEMYEVFKKCKSIGALAQVHAENGKLIEKKSLELISKGITGPEGHLYSRPEEVECEATNRAIMLADQANCPLYVVHVMSKGAADIISDARRQGKVVFGEPIAAGLGTDGSHYSHSCWRHAAGYVMSPPLRNDRNTSKHLMQLLASGDLECTGTDHCVFKASQKALGKDDFRSIPNGVNGVEDRMSVIWEKGVVTGILDPCKFVAVTSTNAAKIFNIYPKKGRIDIGSDADLVLWNPDVRRTISASTHYQNVDFNIFEGMHCHGVAEMVISGGKVVLEDGNLRVAQGTGKFVPTNPFCNYVFNKVKLRDQCHKTLANKVERQPYDGPVEDLSKEMTNLNMNFDDDTDSQQNAISSEFVNTKRPLTSGGGRHMQDSSFALSGAQIDDNLPTR-SGIRTRQPPGG 1845
            +RL IKG +IVNDD+ F AD+Y+EDG+IKQ+G NL++PGGV+ +EANGK++IPGGID HTH + P+ GT + DDF  G++AALAGGTTMI+D VI + GTSL+++Y+Q+R+ AD K CCDY LHV ++ +N+SV  E++ L  + G+NSF+++MAYKD   L + ++YE+F      G + QVHAENG++I ++   ++  GITGPEGH+ SRPEE+E EA  RA+ +A Q NCPLYV  VMSK AADIIS AR++G VVFGEPI A LGTDG+HY    W  AA +V SPPL  D  T  +L  LLASGDL  TG+ HC F  +QKA+GKDDF  IP GVNGVE+RM++IW+K V TG +D   FVA+TSTNAAKI N+YP+KGRI +GSDADL++W+ D  RTI+A TH    ++NIFEGM   G   +VI  GK+VLEDG L+V  G G+F+P +PF ++ + +VK R Q    +   V R  YDGPV + S             +     + S+    TK+P+     R++  S F+L+G    D +P R +G R   PPGG
Sbjct:   99 DRLLIKGGRIVNDDQSFHADIYMEDGLIKQIGDNLIVPGGVKTIEANGKMVIPGGIDIHTHFQMPYRGTTTVDDFAQGSKAALAGGTTMIVDHVIPEPGTSLMEAYDQWRQWADEKACCDYSLHVDITHWNDSVKQEVDSLIKDKGVNSFQVYMAYKDYYQLSNSQLYEIFTFLAEKGGIVQVHAENGEIIAEEQARMLQMGITGPEGHVLSRPEELEAEAVFRAVTIASQTNCPLYVTRVMSKSAADIISQARKKGNVVFGEPITASLGTDGTHYWSKNWAKAAAFVTSPPLSPDPTTPDYLNTLLASGDLSVTGSAHCTFSVAQKAIGKDDFTQIPEGVNGVEERMALIWDKAVTTGKMDENMFVAITSTNAAKILNLYPRKGRIAVGSDADLIIWDTDSVRTITAKTHNSAAEYNIFEGMELRGAPLVVICQGKIVLEDGKLQVTSGAGRFIPCSPFPDFAYKRVKARKQL--AVLRAVPRGMYDGPVSEFSM------------SRGGTPSASARTSPTKQPV-----RNLHQSGFSLTGPPTPDEVPIRPAGRRIVVPPGG 645          
BLAST of Dihydropyrimidinase vs. Ensembl Medaka
Match: dpysl3 (dihydropyrimidinase-related protein 3 [Source:NCBI gene;Acc:101165934])

HSP 1 Score: 610.527 bits (1573), Expect = 0.000e+0
Identity = 287/557 (51.53%), Postives = 386/557 (69.30%), Query Frame = 1
Query:  112 GVKKVPLHLQSSQNRLCIKGAKIVNDDRMFDADVYIEDGIIKQLGTNLVIPGGVRCVEANGKLLIPGGIDTHTHMEFPFMGTVSSDDFYSGTRAALAGGTTMIIDFVIGQKGTSLIDSYNQYREKADSKVCCDYGLHVIVSSYNESVGNEMEKLASEHGINSFKIFMAYKDSLMLEDDEMYEVFKKCKSIGALAQVHAENGKLIEKKSLELISKGITGPEGHLYSRPEEVECEATNRAIMLADQANCPLYVVHVMSKGAADIISDARRQGKVVFGEPIAAGLGTDGSHYSHSCWRHAAGYVMSPPLRNDRNTSKHLMQLLASGDLECTGTDHCVFKASQKALGKDDFRSIPNGVNGVEDRMSVIWEKGVVTGILDPCKFVAVTSTNAAKIFNIYPKKGRIDIGSDADLVLWNPDVRRTISASTHYQNVDFNIFEGMHCHGVAEMVISGGKVVLEDGNLRVAQGTGKFVPTNPFCNYVFNKVKLRDQCHKTLANKVERQPYDGPVEDLSKEMTNLNMNFDDDTDSQQNAISSEFVNTKRPLTSGGGRHMQDSSFALSG 1782
            G K +P   + + +RL IKG +IVNDD+ F AD+Y+EDG+IKQ+G NL++PGGV+ +EANGK++IPGGID HTH + P+ GT + DDF  G++AALAGGTTMI+D VI + GTSL+++Y+Q+R+ AD K CCDY LHV ++ +N+SV  E++ L  + G+NSF+++MAYKD   L + ++YE+F      G + QVHAENG++I ++   ++  GITGPEGH+ SRPEE+E EA  RA+ +A Q NCPLYV  VMSK AADIIS AR++G VVFGEPI A LGTDG+HY    W  AA +V SPPL  D  T  +L  LLASGDL  TG+ HC F  +QKA+GKDDF  IP GVNGVE+RM++IW+K V TG +D   FVA+TSTNAAKI N+YP+KGRI +GSDADL++W+ D  RTI+A TH    ++NIFEGM   G   +VI  GK+VLEDG L+V  G G+F+P +PF ++ + +VK R Q    +   V R  YDGPV + S             +     + S+    TK+P+     R++  S F+L+G
Sbjct:    5 GKKNIP---KITSDRLLIKGGRIVNDDQSFHADIYMEDGLIKQIGDNLIVPGGVKTIEANGKMVIPGGIDIHTHFQMPYRGTTTVDDFAQGSKAALAGGTTMIVDHVIPEPGTSLMEAYDQWRQWADEKACCDYSLHVDITHWNDSVKQEVDSLIKDKGVNSFQVYMAYKDYYQLSNSQLYEIFTFLAEKGGIVQVHAENGEIIAEEQARMLQMGITGPEGHVLSRPEELEAEAVFRAVTIASQTNCPLYVTRVMSKSAADIISQARKKGNVVFGEPITASLGTDGTHYWSKNWAKAAAFVTSPPLSPDPTTPDYLNTLLASGDLSVTGSAHCTFSVAQKAIGKDDFTQIPEGVNGVEERMALIWDKAVTTGKMDENMFVAITSTNAAKILNLYPRKGRIAVGSDADLIIWDTDSVRTITAKTHNSAAEYNIFEGMELRGAPLVVICQGKIVLEDGKLQVTSGAGRFIPCSPFPDFAYKRVKARKQL--AVLRAVPRGMYDGPVSEFSM------------SRGGTPSASARTSPTKQPV-----RNLHQSGFSLTG 539          
BLAST of Dihydropyrimidinase vs. Ensembl Medaka
Match: DPYSL2 (dihydropyrimidinase-related protein 2 [Source:NCBI gene;Acc:101174435])

HSP 1 Score: 598.201 bits (1541), Expect = 0.000e+0
Identity = 297/586 (50.68%), Postives = 402/586 (68.60%), Query Frame = 1
Query:  112 GVKKVPLHLQSSQNRLCIKGAKIVNDDRMFDADVYIEDGIIKQLGTNLVIPGGVRCVEANGKLLIPGGIDTHTHMEFPFMGTVSSDDFYSGTRAALAGGTTMIIDFVIGQKGTSLIDSYNQYREKADSKVCCDYGLHVIVSSYNESVGNEMEKLASEHGINSFKIFMAYKDSLMLEDDEMYEVFKKCKSIGALAQVHAENGKLIEKKSLELISKGITGPEGHLYSRPE-EVECEATNRAIMLADQANCPLYVVHVMSKGAADIISDARRQGKVVFGEPIAAGLGTDGSHYSHSCWRHAAGYVMSPPLRNDRNTSKHLMQLLASGDLECTGTDHCVFKASQKALGKDDFRSIPNGVNGVEDRMSVIWEKGVVTGILDPCKFVAVTSTNAAKIFNIYPKKGRIDIGSDADLVLWNPDVRRTISASTHYQNVDFNIFEGMHCHGVAEMVISGGKVVLEDGNLRVAQGTGKFVPTNPFCNYVFNKVKLRDQCHKTLANKVERQPYDGPVEDLSKEMTNLNMNFDDDTDSQQNAISSEFVNTKRPLTSGGGRHMQDSSFALSGAQIDDNLPTRSGIRTRQPPGGTA--TSL 1860
            G K +P   + + +RL IKGAKIVNDD+ F AD+Y+EDG+IKQ+G NL++PGGV+ +EA+G++++PGGID HT  + P  G V++DDFY GTRAALAGGTTMIID  + + GTSL+ ++ Q+RE ADSK CCDY LHV ++ +N     EME L  +HG+NSF +++AYKD   L D +MYEVF   + +GA+AQVHAENG +I ++          GP   L SR   +VE EA NRA+ +A+Q NCPLY+  VMSK AAD+I+ AR++G VV+GEPI+A LGTDG+HY    W  AA +V SPPL  D  T  +L  LL+ GDL+ TG+ HC FK SQ+A+GKD+F  IP G NG E+RMS++W+K VVTG +D  +FVAVTSTNAAKIFN+YP+KGRI +GSDADLVLW+PD+ + ISA +H  +V++NIFEG    G   +VIS GK+VLEDGNL   +G G+++    F ++V+ ++K R +   T    V R  YDGPV D++     ++      T   +     +   +++P+     R++  S F+LSGAQIDDN+P R+  R   PPGG A  TSL
Sbjct:    6 GKKNIP---RITSDRLLIKGAKIVNDDQSFVADLYMEDGVIKQIGDNLIVPGGVKIIEAHGRMVMPGGIDVHTRFQMPDRGMVAADDFYQGTRAALAGGTTMIIDHAVPEPGTSLVSAFKQWREWADSKSCCDYSLHVDITEWNSGTQEEMETLVKDHGVNSFLVYLAYKDIFQLSDSQMYEVFSFIRDLGAIAQVHAENGDIIAERR---------GPFLCLTSRHVLQVEAEAVNRAVTVANQTNCPLYITKVMSKSAADVIALARKKGAVVYGEPISASLGTDGTHYWSKNWAKAAAFVTSPPLSPDPTTPDYLNSLLSCGDLQVTGSAHCTFKTSQRAVGKDNFTMIPEGTNGTEERMSLVWDKCVVTGKMDENQFVAVTSTNAAKIFNLYPRKGRIAVGSDADLVLWDPDMMKIISAKSHNLSVEYNIFEGTEVRGGPLVVISQGKIVLEDGNLHTTEGCGRYISRKAFPDHVYKRIKARSRL--TELRGVPRGQYDGPVCDVAVTPKVISTVSSVKTSPAKQQQQQQQQVSQQPV-----RNLHQSGFSLSGAQIDDNVPRRTTQRIVAPPGGKANITSL 572          
BLAST of Dihydropyrimidinase vs. Planmine SMEST
Match: SMESG000002633.1 (SMESG000002633.1)

HSP 1 Score: 1236.09 bits (3197), Expect = 0.000e+0
Identity = 592/592 (100.00%), Postives = 592/592 (100.00%), Query Frame = 1
Query:   88 MNDSKVNIGVKKVPLHLQSSQNRLCIKGAKIVNDDRMFDADVYIEDGIIKQLGTNLVIPGGVRCVEANGKLLIPGGIDTHTHMEFPFMGTVSSDDFYSGTRAALAGGTTMIIDFVIGQKGTSLIDSYNQYREKADSKVCCDYGLHVIVSSYNESVGNEMEKLASEHGINSFKIFMAYKDSLMLEDDEMYEVFKKCKSIGALAQVHAENGKLIEKKSLELISKGITGPEGHLYSRPEEVECEATNRAIMLADQANCPLYVVHVMSKGAADIISDARRQGKVVFGEPIAAGLGTDGSHYSHSCWRHAAGYVMSPPLRNDRNTSKHLMQLLASGDLECTGTDHCVFKASQKALGKDDFRSIPNGVNGVEDRMSVIWEKGVVTGILDPCKFVAVTSTNAAKIFNIYPKKGRIDIGSDADLVLWNPDVRRTISASTHYQNVDFNIFEGMHCHGVAEMVISGGKVVLEDGNLRVAQGTGKFVPTNPFCNYVFNKVKLRDQCHKTLANKVERQPYDGPVEDLSKEMTNLNMNFDDDTDSQQNAISSEFVNTKRPLTSGGGRHMQDSSFALSGAQIDDNLPTRSGIRTRQPPGGTATSLW 1863
            MNDSKVNIGVKKVPLHLQSSQNRLCIKGAKIVNDDRMFDADVYIEDGIIKQLGTNLVIPGGVRCVEANGKLLIPGGIDTHTHMEFPFMGTVSSDDFYSGTRAALAGGTTMIIDFVIGQKGTSLIDSYNQYREKADSKVCCDYGLHVIVSSYNESVGNEMEKLASEHGINSFKIFMAYKDSLMLEDDEMYEVFKKCKSIGALAQVHAENGKLIEKKSLELISKGITGPEGHLYSRPEEVECEATNRAIMLADQANCPLYVVHVMSKGAADIISDARRQGKVVFGEPIAAGLGTDGSHYSHSCWRHAAGYVMSPPLRNDRNTSKHLMQLLASGDLECTGTDHCVFKASQKALGKDDFRSIPNGVNGVEDRMSVIWEKGVVTGILDPCKFVAVTSTNAAKIFNIYPKKGRIDIGSDADLVLWNPDVRRTISASTHYQNVDFNIFEGMHCHGVAEMVISGGKVVLEDGNLRVAQGTGKFVPTNPFCNYVFNKVKLRDQCHKTLANKVERQPYDGPVEDLSKEMTNLNMNFDDDTDSQQNAISSEFVNTKRPLTSGGGRHMQDSSFALSGAQIDDNLPTRSGIRTRQPPGGTATSLW
Sbjct:    1 MNDSKVNIGVKKVPLHLQSSQNRLCIKGAKIVNDDRMFDADVYIEDGIIKQLGTNLVIPGGVRCVEANGKLLIPGGIDTHTHMEFPFMGTVSSDDFYSGTRAALAGGTTMIIDFVIGQKGTSLIDSYNQYREKADSKVCCDYGLHVIVSSYNESVGNEMEKLASEHGINSFKIFMAYKDSLMLEDDEMYEVFKKCKSIGALAQVHAENGKLIEKKSLELISKGITGPEGHLYSRPEEVECEATNRAIMLADQANCPLYVVHVMSKGAADIISDARRQGKVVFGEPIAAGLGTDGSHYSHSCWRHAAGYVMSPPLRNDRNTSKHLMQLLASGDLECTGTDHCVFKASQKALGKDDFRSIPNGVNGVEDRMSVIWEKGVVTGILDPCKFVAVTSTNAAKIFNIYPKKGRIDIGSDADLVLWNPDVRRTISASTHYQNVDFNIFEGMHCHGVAEMVISGGKVVLEDGNLRVAQGTGKFVPTNPFCNYVFNKVKLRDQCHKTLANKVERQPYDGPVEDLSKEMTNLNMNFDDDTDSQQNAISSEFVNTKRPLTSGGGRHMQDSSFALSGAQIDDNLPTRSGIRTRQPPGGTATSLW 592          
BLAST of Dihydropyrimidinase vs. Planmine SMEST
Match: SMESG000028784.1 (SMESG000028784.1)

HSP 1 Score: 382.874 bits (982), Expect = 4.374e-125
Identity = 216/573 (37.70%), Postives = 329/573 (57.42%), Query Frame = 1
Query:  154 RLCIKGAKIVNDDRMFDADVYIEDGIIKQLGTNLVIPGGVRCVEANGKLLIPGGIDTHTHMEFPFMGTVSSDDFYSGTRAALAGGTTMIIDFVIGQKGTSLIDSYNQYREKADSKVCCDYGLHVIVSSYNESVGNEMEKLASEHGINSFKIFMAYKDSLMLEDDEMYEVFKKCKSIGALAQVHAENGKLIEKKSLELISKGITGPEGHLYSRPEEVECEATNRAIMLADQANCPLYVVHVMSKGAADIISDARRQGKVVFGEPIAAGLGTDGSHYSHSCWRHAAGYVMSPPLRNDRNTSKHLMQLLASGDLECTGTDHCVFKASQKALGKDDFRSIPNGVNGVEDRMSVIWEKGVVTGILDPCKFVAVTSTNAAKIFNIYPKKGRIDIGSDADLVLWNPDVRRTISA-STHYQNVDFNIFEGMHCHGVAEMVISGGKVVLEDGNLRVAQGTGKFVPTNPFCNYVFNKVKLRDQCHKTLANK-VERQPYDGP-VEDLSKEMTNLNMNFDDDTDSQQNAISSEFVNTKRPLTSGGGRHMQDSSFALSGAQIDDNLPTRSGIRTRQPPGGTATSLW 1863
            ++ +KG  IVN DR F +DV IE+ IIKQ+G ++V+ G  + ++   KL+IPGGID  T+     +     D  ++ + AALAGGTT II  V  Q G  L++S    +    SKV C+YG  V +   ++     MEKLA + GIN F++ +  +      +     V KKCK +  L ++   +   +E    ELI+ GI+GPEG   SR  E E E   R + L     C L +  VM++  A +++  + +G+ +F E I   L      Y  + W  +A  +  PP+RND++ +  +++ +  GD++   ++H     + +++GK DFR+IP+GV+GVE+R+S++W++GV +GI++ C+FV+ TSTNAAKIFN+YP +G I +GS AD+V+WNP   RTISA S H QN D NIFEG+ C GV E+VI  G V  +  N  +   TG+ +     C  V +K+K R +C +      + R+  D   V    + + N +     D  +  + I+   +  +RP TSGG R+MQDSSF+LSG+QIDD  P RS IRT  PPGG +  ++
Sbjct:    2 KMLLKGGYIVNSDRKFQSDVLIENNIIKQIGQSIVVSGDTKVIDVTNKLIIPGGIDPSTNFN---LSPNHRDILHNESMAALAGGTTTIITLVKEQSGAELVNSLKALQSDLKSKVLCNYGFCVQIDPNDDECVKSMEKLARQFGINCFQMTIGNEI-----NANTVSVLKKCKELQCLLKLRVHDSTYLEAVEEELITAGISGPEGFFQSRCIENEMEQLYRILKLNHVFPCCLIIPQVMNEDIAKLVAKMKMEGRPIFSETIPPALALSSHKYFSNNWDESASLITDPPVRNDQDAA--IIRSIHCGDIDMVASEHTTITNADRSIGKRDFRNIPHGVSGVEERLSMLWDRGVKSGIINECEFVSATSTNAAKIFNLYPDRGHIAVGSVADIVIWNPVKTRTISALSQHLQN-DTNIFEGISCQGVPEVVIVNGSVKFQ-LNEFIGNATGERIDLKINCQVVKDKMK-RYECLREFGKMGITREISDNIGVASEIRTINNSHKVIQKDIVTVDSKINP--LKMQRPPTSGGNRNMQDSSFSLSGSQIDDEKPIRSTIRTNHPPGGKSNLIF 559          
BLAST of Dihydropyrimidinase vs. Planmine SMEST
Match: SMESG000028784.1 (SMESG000028784.1)

HSP 1 Score: 382.104 bits (980), Expect = 9.207e-125
Identity = 216/572 (37.76%), Postives = 328/572 (57.34%), Query Frame = 1
Query:  157 LCIKGAKIVNDDRMFDADVYIEDGIIKQLGTNLVIPGGVRCVEANGKLLIPGGIDTHTHMEFPFMGTVSSDDFYSGTRAALAGGTTMIIDFVIGQKGTSLIDSYNQYREKADSKVCCDYGLHVIVSSYNESVGNEMEKLASEHGINSFKIFMAYKDSLMLEDDEMYEVFKKCKSIGALAQVHAENGKLIEKKSLELISKGITGPEGHLYSRPEEVECEATNRAIMLADQANCPLYVVHVMSKGAADIISDARRQGKVVFGEPIAAGLGTDGSHYSHSCWRHAAGYVMSPPLRNDRNTSKHLMQLLASGDLECTGTDHCVFKASQKALGKDDFRSIPNGVNGVEDRMSVIWEKGVVTGILDPCKFVAVTSTNAAKIFNIYPKKGRIDIGSDADLVLWNPDVRRTISA-STHYQNVDFNIFEGMHCHGVAEMVISGGKVVLEDGNLRVAQGTGKFVPTNPFCNYVFNKVKLRDQCHKTLANK-VERQPYDGP-VEDLSKEMTNLNMNFDDDTDSQQNAISSEFVNTKRPLTSGGGRHMQDSSFALSGAQIDDNLPTRSGIRTRQPPGGTATSLW 1863
            + +KG  IVN DR F +DV IE+ IIKQ+G ++V+ G  + ++   KL+IPGGID  T+     +     D  ++ + AALAGGTT II  V  Q G  L++S    +    SKV C+YG  V +   ++     MEKLA + GIN F++ +  +      +     V KKCK +  L ++   +   +E    ELI+ GI+GPEG   SR  E E E   R + L     C L +  VM++  A +++  + +G+ +F E I   L      Y  + W  +A  +  PP+RND++ +  +++ +  GD++   ++H     + +++GK DFR+IP+GV+GVE+R+S++W++GV +GI++ C+FV+ TSTNAAKIFN+YP +G I +GS AD+V+WNP   RTISA S H QN D NIFEG+ C GV E+VI  G V  +  N  +   TG+ +     C  V +K+K R +C +      + R+  D   V    + + N +     D  +  + I+   +  +RP TSGG R+MQDSSF+LSG+QIDD  P RS IRT  PPGG +  ++
Sbjct:    1 MLLKGGYIVNSDRKFQSDVLIENNIIKQIGQSIVVSGDTKVIDVTNKLIIPGGIDPSTNFN---LSPNHRDILHNESMAALAGGTTTIITLVKEQSGAELVNSLKALQSDLKSKVLCNYGFCVQIDPNDDECVKSMEKLARQFGINCFQMTIGNEI-----NANTVSVLKKCKELQCLLKLRVHDSTYLEAVEEELITAGISGPEGFFQSRCIENEMEQLYRILKLNHVFPCCLIIPQVMNEDIAKLVAKMKMEGRPIFSETIPPALALSSHKYFSNNWDESASLITDPPVRNDQDAA--IIRSIHCGDIDMVASEHTTITNADRSIGKRDFRNIPHGVSGVEERLSMLWDRGVKSGIINECEFVSATSTNAAKIFNLYPDRGHIAVGSVADIVIWNPVKTRTISALSQHLQN-DTNIFEGISCQGVPEVVIVNGSVKFQ-LNEFIGNATGERIDLKINCQVVKDKMK-RYECLREFGKMGITREISDNIGVASEIRTINNSHKVIQKDIVTVDSKINP--LKMQRPPTSGGNRNMQDSSFSLSGSQIDDEKPIRSTIRTNHPPGGKSNLIF 557          
BLAST of Dihydropyrimidinase vs. Planmine SMEST
Match: SMESG000060188.1 (SMESG000060188.1)

HSP 1 Score: 322.013 bits (824), Expect = 1.312e-101
Identity = 191/587 (32.54%), Postives = 312/587 (53.15%), Query Frame = 1
Query:  136 LQSSQNRLCIKGAKIVNDDRMFDADVYIEDGIIKQLGTNLVIPGGVRCVEANGKLLIPGGIDTHTHMEFPFMGTVSSDDFYSGTRAALAGGTTMIIDFVIGQKGTSLIDSYNQYREKADSKVCCDYGLHVIVSSYNESVGNEMEKLASEHGINSFKIFMAYKDS----LMLEDDEMYEVFKKCKSIGALAQVHAENGKLIEKKSLELISKGITGPEGHLYSRPEEVECEATNRAIMLADQANCPLYVVHVMSKGAADIISDARRQGK--VVFGEPIAAGLGTDGSHYSHSCWRHAAGYVMSPPLRNDRNTS---KHLMQLLASGDLECTGTDHCVFKASQKALGKDDFRSIPNGVNGVEDRMSVIWEKGVVTGILDPCKFVAVTSTNAAKIFNIYPKKGRIDIGSDADLVLWNPDVRRTISASTHYQNVDFNIFEGMHCHGVAEMVISGGKVVLE-DGNLRVAQGTGKFV-PTNPFCNYVFNKVKLRDQCHKTLANKVERQPYDGPVEDLSKEMTNLNMNFDDDTDSQQNAISSEFVNTKRPLTSGGGRHMQDSSFALSGAQIDDNLPTRSGIRTRQPPGGTATSLW 1863
            +  +Q +L IK   ++N D  +DADV IE+G I  +  N+       C++A G  ++PGG+D  T+      G VS ++++SGT+AA+ GGTT +++ +   K  SL + Y   ++    ++ C+  + + +   NE++ +E  +L     +    + ++  D     + ++D+E+Y+    C+    L  VHAEN K++     EL++ G+TGPEGH  SRPE+VE EA  R + +A+   CP++   V +K + D I D +R+    ++ G  + A L  +   Y    W+ AA +V  P L+ ++NT      L++ +AS  +    + H VF    KA G++DFR I  G NGV+ RM ++W+K V +G ++P  FV   ST  AK+ NIYP KG I IGSDAD+++W  D   ++S S +++  D N+FE + CH   + VI  G VVL+ +GN   ++G+G+ V P+    N  F K  +  +    +  K+ R+PYDGPV D S            D   +++ + S  VN         G   +D   AL   Q       R+ ++T QPPGG+A + W
Sbjct:    1 MSETQKKLLIKCGTVINHDCTYDADVLIENGKIVNIAKNIE-DSLAECIDATGCFVLPGGVDAETNFAAKRGGIVSPENYFSGTKAAIYGGTTTVVNCLEIMKDESLKEKYEMEKDIISKEIVCNLAIQLCLPEVNEAIKSEFNELLQSKSVVPL-VRLSTVDKGCHCVKIDDEELYDALCWCRDNSVLPTVHAENDKMVAILEKELLADGVTGPEGHYLSRPEKVEDEAVFRVLTIAEMVKCPIHFGKVYAKSSLDKIMDWQRKSSNTIICGTSLVA-LVHNAEKYRDPNWKVAASFVTMPALKMNKNTEFQCTELLETVASRKINHVASSHLVFDMKHKASGRNDFRCIIPGTNGVQYRMKILWDKAVKSGRMEPTSFVNCVSTTPAKLANIYPHKGTISIGSDADIIVWKGD---SVSHS-NFEAGDINVFEDVICHSGPKYVIVNGIVVLDHEGNFTASKGSGQIVSPSLETMNSYFQKQLINYKLSNEVEKKIAREPYDGPVIDPSA-----------DNKEEKHVLYSHMVNND---VYKRGGPAEDKKEALPPGQ----RVIRTSVKTAQPPGGSAQASW 562          
BLAST of Dihydropyrimidinase vs. Planmine SMEST
Match: SMESG000060188.1 (SMESG000060188.1)

HSP 1 Score: 322.013 bits (824), Expect = 1.551e-101
Identity = 191/584 (32.71%), Postives = 311/584 (53.25%), Query Frame = 1
Query:  145 SQNRLCIKGAKIVNDDRMFDADVYIEDGIIKQLGTNLVIPGGVRCVEANGKLLIPGGIDTHTHMEFPFMGTVSSDDFYSGTRAALAGGTTMIIDFVIGQKGTSLIDSYNQYREKADSKVCCDYGLHVIVSSYNESVGNEMEKLASEHGINSFKIFMAYKDS----LMLEDDEMYEVFKKCKSIGALAQVHAENGKLIEKKSLELISKGITGPEGHLYSRPEEVECEATNRAIMLADQANCPLYVVHVMSKGAADIISDARRQGK--VVFGEPIAAGLGTDGSHYSHSCWRHAAGYVMSPPLRNDRNTS---KHLMQLLASGDLECTGTDHCVFKASQKALGKDDFRSIPNGVNGVEDRMSVIWEKGVVTGILDPCKFVAVTSTNAAKIFNIYPKKGRIDIGSDADLVLWNPDVRRTISASTHYQNVDFNIFEGMHCHGVAEMVISGGKVVLE-DGNLRVAQGTGKFV-PTNPFCNYVFNKVKLRDQCHKTLANKVERQPYDGPVEDLSKEMTNLNMNFDDDTDSQQNAISSEFVNTKRPLTSGGGRHMQDSSFALSGAQIDDNLPTRSGIRTRQPPGGTATSLW 1863
            +Q +L IK   ++N D  +DADV IE+G I  +  N+       C++A G  ++PGG+D  T+      G VS ++++SGT+AA+ GGTT +++ +   K  SL + Y   ++    ++ C+  + + +   NE++ +E  +L     +    + ++  D     + ++D+E+Y+    C+    L  VHAEN K++     EL++ G+TGPEGH  SRPE+VE EA  R + +A+   CP++   V +K + D I D +R+    ++ G  + A L  +   Y    W+ AA +V  P L+ ++NT      L++ +AS  +    + H VF    KA G++DFR I  G NGV+ RM ++W+K V +G ++P  FV   ST  AK+ NIYP KG I IGSDAD+++W  D   ++S S +++  D N+FE + CH   + VI  G VVL+ +GN   ++G+G+ V P+    N  F K  +  +    +  K+ R+PYDGPV D S            D   +++ + S  VN         G   +D   AL   Q       R+ ++T QPPGG+A + W
Sbjct:    7 TQKKLLIKCGTVINHDCTYDADVLIENGKIVNIAKNIE-DSLAECIDATGCFVLPGGVDAETNFAAKRGGIVSPENYFSGTKAAIYGGTTTVVNCLEIMKDESLKEKYEMEKDIISKEIVCNLAIQLCLPEVNEAIKSEFNELLQSKSVVPL-VRLSTVDKGCHCVKIDDEELYDALCWCRDNSVLPTVHAENDKMVAILEKELLADGVTGPEGHYLSRPEKVEDEAVFRVLTIAEMVKCPIHFGKVYAKSSLDKIMDWQRKSSNTIICGTSLVA-LVHNAEKYRDPNWKVAASFVTMPALKMNKNTEFQCTELLETVASRKINHVASSHLVFDMKHKASGRNDFRCIIPGTNGVQYRMKILWDKAVKSGRMEPTSFVNCVSTTPAKLANIYPHKGTISIGSDADIIVWKGD---SVSHS-NFEAGDINVFEDVICHSGPKYVIVNGIVVLDHEGNFTASKGSGQIVSPSLETMNSYFQKQLINYKLSNEVEKKIAREPYDGPVIDPSA-----------DNKEEKHVLYSHMVNND---VYKRGGPAEDKKEALPPGQ----RVIRTSVKTAQPPGGSAQASW 565          
The following BLAST results are available for this feature:
BLAST of Dihydropyrimidinase vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
DPYSL20.000e+052.31dihydropyrimidinase like 2 [Source:HGNC Symbol;Acc... [more]
DPYSL20.000e+052.42dihydropyrimidinase like 2 [Source:HGNC Symbol;Acc... [more]
DPYS0.000e+059.84dihydropyrimidinase [Source:HGNC Symbol;Acc:HGNC:3... [more]
DPYSL30.000e+051.21dihydropyrimidinase like 3 [Source:HGNC Symbol;Acc... [more]
DPYSL30.000e+051.40dihydropyrimidinase like 3 [Source:HGNC Symbol;Acc... [more]
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BLAST of Dihydropyrimidinase vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
dhp-20.000e+056.26Dihydropyrimidinase 2 [Source:UniProtKB/Swiss-Pro... [more]
dhp-10.000e+054.85Dihydropyrimidinase 1 [Source:UniProtKB/Swiss-Pro... [more]
dhp-10.000e+054.85Dihydropyrimidinase 1 [Source:UniProtKB/Swiss-Pro... [more]
dhp-10.000e+054.85Dihydropyrimidinase 1 [Source:UniProtKB/Swiss-Pro... [more]
unc-331.034e-9233.33pep chromosome:WBcel235:IV:3518147:3525572:1 gene:... [more]
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BLAST of Dihydropyrimidinase vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
CRMP0.000e+050.75gene:FBgn0023023 transcript:FBtr0114453[more]
CRMP0.000e+049.08gene:FBgn0023023 transcript:FBtr0089686[more]
CRMP1.021e-12054.94gene:FBgn0023023 transcript:FBtr0089685[more]
CG61067.147e-1021.94gene:FBgn0030914 transcript:FBtr0343296[more]
CG61067.147e-1021.94gene:FBgn0030914 transcript:FBtr0074553[more]
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BLAST of Dihydropyrimidinase vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
dpysl2b0.000e+052.95dihydropyrimidinase like 2b [Source:ZFIN;Acc:ZDB-G... [more]
dpys0.000e+060.73dihydropyrimidinase [Source:ZFIN;Acc:ZDB-GENE-0705... [more]
FO904844.10.000e+052.13dihydropyrimidinase like 2a [Source:NCBI gene;Acc:... [more]
dpysl30.000e+051.30dihydropyrimidinase like 3 [Source:NCBI gene;Acc:5... [more]
dpysl40.000e+051.15dihydropyrimidinase like 4 [Source:ZFIN;Acc:ZDB-GE... [more]
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BLAST of Dihydropyrimidinase vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
bco20.000e+052.31beta-carotene oxygenase 2 [Source:Xenbase;Acc:XB-G... [more]
bco20.000e+052.60beta-carotene oxygenase 2 [Source:Xenbase;Acc:XB-G... [more]
bco20.000e+052.60beta-carotene oxygenase 2 [Source:Xenbase;Acc:XB-G... [more]
bco20.000e+052.97beta-carotene oxygenase 2 [Source:Xenbase;Acc:XB-G... [more]
bco20.000e+052.97beta-carotene oxygenase 2 [Source:Xenbase;Acc:XB-G... [more]
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BLAST of Dihydropyrimidinase vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Dpysl20.000e+052.31dihydropyrimidinase-like 2 [Source:MGI Symbol;Acc:... [more]
Dpys0.000e+058.91dihydropyrimidinase [Source:MGI Symbol;Acc:MGI:192... [more]
Dpys0.000e+058.91dihydropyrimidinase [Source:MGI Symbol;Acc:MGI:192... [more]
Dpysl40.000e+051.04dihydropyrimidinase-like 4 [Source:MGI Symbol;Acc:... [more]
Dpysl40.000e+051.04dihydropyrimidinase-like 4 [Source:MGI Symbol;Acc:... [more]
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BLAST of Dihydropyrimidinase vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q90635|DPYL2_CHICK0.000e+052.82Dihydropyrimidinase-related protein 2 OS=Gallus ga... [more]
sp|Q63150|DPYS_RAT0.000e+059.50Dihydropyrimidinase OS=Rattus norvegicus OX=10116 ... [more]
sp|P47942|DPYL2_RAT0.000e+052.31Dihydropyrimidinase-related protein 2 OS=Rattus no... [more]
sp|O08553|DPYL2_MOUSE0.000e+052.31Dihydropyrimidinase-related protein 2 OS=Mus muscu... [more]
sp|O02675|DPYL2_BOVIN0.000e+052.31Dihydropyrimidinase-related protein 2 OS=Bos tauru... [more]
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BLAST of Dihydropyrimidinase vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A0X3NYF80.000e+066.72Dihydropyrimidinase (Fragment) OS=Schistocephalus ... [more]
A0A3P7D5Z00.000e+067.17Amidohydro-rel domain-containing protein OS=Schist... [more]
A0A183TGQ20.000e+067.17Dihydropyrimidinase OS=Schistocephalus solidus OX=... [more]
A0A0R3W2S30.000e+064.61Amidohydro-rel domain-containing protein OS=Taenia... [more]
A0A075A1G20.000e+065.55Amidohydro-rel domain-containing protein OS=Opisth... [more]
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BLAST of Dihydropyrimidinase vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
dpysl2b0.000e+051.79dihydropyrimidinase-related protein 2 [Source:NCBI... [more]
dpysl2b0.000e+051.63dihydropyrimidinase-related protein 2 [Source:NCBI... [more]
dpys0.000e+060.83dihydropyrimidinase [Source:ZFIN;Acc:ZDB-GENE-0705... [more]
DPYSL20.000e+055.12dihydropyrimidinase like 2 [Source:HGNC Symbol;Acc... [more]
dpysl40.000e+050.00dihydropyrimidinase like 4 [Source:NCBI gene;Acc:1... [more]
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BLAST of Dihydropyrimidinase vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 4
Match NameE-valueIdentityDescription
dpysl36.491e-17250.63dihydropyrimidinase like 3 [Source:NCBI gene;Acc:5... [more]
dpysl2b8.303e-10855.86dihydropyrimidinase like 2b [Source:ZFIN;Acc:ZDB-G... [more]
ENSPMAT00000006054.11.600e-8349.81pep scaffold:Pmarinus_7.0:GL477305:540:7425:1 gene... [more]
ENSPMAT00000004226.14.157e-626.47pep scaffold:Pmarinus_7.0:GL477658:179183:185371:1... [more]
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BLAST of Dihydropyrimidinase vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 1
Match NameE-valueIdentityDescription
DAL15.724e-2225.00Allantoinase; converts allantoin to allantoate in ... [more]
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BLAST of Dihydropyrimidinase vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO465510.000e+058.32Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO491581.062e-2423.86Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO258041.210e-1128.16Predicted protein [Source:UniProtKB/TrEMBL;Acc:A8... [more]
EDO290832.375e-735.71Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO377032.473e-735.71Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Dihydropyrimidinase vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
dpys0.000e+061.54dihydropyrimidinase [Source:NCBI gene;Acc:10116118... [more]
dpysl2b0.000e+052.04dihydropyrimidinase-related protein 2 [Source:NCBI... [more]
dpysl30.000e+051.77dihydropyrimidinase-related protein 3 [Source:NCBI... [more]
dpysl30.000e+051.53dihydropyrimidinase-related protein 3 [Source:NCBI... [more]
DPYSL20.000e+050.68dihydropyrimidinase-related protein 2 [Source:NCBI... [more]
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BLAST of Dihydropyrimidinase vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000002633.10.000e+0100.00SMESG000002633.1[more]
SMESG000028784.14.374e-12537.70SMESG000028784.1[more]
SMESG000028784.19.207e-12537.76SMESG000028784.1[more]
SMESG000060188.11.312e-10132.54SMESG000060188.1[more]
SMESG000060188.11.551e-10132.71SMESG000060188.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30009564 ID=SMED30009564|Name=Dihydropyrimidinase|organism=Schmidtea mediterranea sexual|type=transcript|length=2022bp
ATTTAGTTTAACTTAAACTATTTGTTATTATATATTTGAATATATTCACG
ATTCGTAACGAAGTGATTTCTTCTGAAAATTATTAAAATGAATGATTCTA
AAGTCAACATTGGTGTGAAAAAAGTACCTCTTCATTTACAGAGCTCTCAA
AATAGGCTCTGTATAAAAGGGGCTAAAATTGTAAATGACGATCGTATGTT
TGATGCTGACGTTTACATCGAGGATGGAATAATCAAACAATTAGGAACTA
ATCTTGTTATTCCTGGGGGCGTTAGGTGTGTTGAAGCCAATGGGAAATTG
CTCATTCCCGGTGGTATTGATACGCACACGCATATGGAATTTCCATTTAT
GGGTACTGTCTCGTCTGACGATTTCTATTCTGGTACAAGAGCTGCACTAG
CAGGGGGAACGACAATGATCATCGATTTTGTTATCGGTCAGAAAGGTACA
TCGTTAATTGACAGTTATAATCAATACCGGGAGAAAGCTGATTCAAAAGT
ATGTTGTGACTATGGACTGCATGTCATTGTTTCATCATACAATGAATCTG
TCGGGAATGAAATGGAAAAACTCGCTAGCGAACACGGCATAAACTCTTTT
AAGATTTTTATGGCATATAAAGACAGTTTGATGCTGGAGGATGATGAAAT
GTATGAAGTGTTTAAAAAATGCAAAAGTATCGGAGCTCTGGCTCAAGTTC
ACGCAGAGAATGGCAAATTAATCGAAAAGAAGTCACTGGAATTAATCTCC
AAAGGGATAACAGGTCCAGAAGGACATTTGTATTCGCGACCTGAAGAAGT
TGAATGTGAGGCCACTAATCGCGCGATAATGCTAGCTGATCAAGCTAACT
GTCCTCTTTACGTTGTCCATGTGATGAGTAAGGGTGCTGCTGATATTATC
TCAGACGCTAGAAGGCAGGGCAAAGTGGTTTTTGGTGAGCCAATCGCTGC
CGGTTTGGGCACAGATGGATCGCATTATAGCCACAGTTGTTGGCGACACG
CTGCAGGATATGTTATGAGTCCTCCGTTGAGAAATGACCGCAACACGAGT
AAGCATCTCATGCAACTACTTGCCAGTGGAGATCTTGAATGCACTGGAAC
AGATCACTGCGTTTTTAAAGCTTCTCAGAAAGCTTTAGGTAAAGATGATT
TCCGCAGTATTCCGAATGGTGTGAACGGAGTAGAAGATCGTATGTCGGTT
ATTTGGGAGAAAGGAGTGGTTACTGGTATTTTGGATCCCTGCAAATTTGT
AGCCGTTACGAGCACAAATGCTGCCAAAATTTTCAATATCTATCCAAAAA
AAGGTCGAATCGATATCGGATCAGACGCTGATCTGGTTTTGTGGAATCCT
GACGTGAGACGAACGATTTCCGCCTCGACACATTATCAAAATGTCGATTT
CAACATATTTGAAGGAATGCACTGTCACGGGGTGGCAGAAATGGTAATTT
CCGGTGGCAAGGTAGTTCTGGAGGATGGGAATTTGCGAGTGGCACAAGGC
ACCGGGAAATTTGTCCCGACTAATCCCTTCTGCAATTATGTGTTTAATAA
AGTGAAATTGAGAGATCAATGCCACAAGACTCTGGCCAATAAGGTCGAGA
GGCAGCCGTATGACGGACCAGTGGAGGACTTGTCGAAGGAAATGACAAAT
CTGAATATGAATTTTGATGATGATACCGATAGTCAACAGAATGCCATTTC
TTCAGAATTCGTTAATACTAAGCGACCGCTTACGTCCGGTGGAGGCAGGC
ATATGCAGGATTCCAGTTTTGCTCTGAGTGGTGCTCAAATAGATGACAAT
CTACCAACACGCTCTGGAATCCGCACTCGCCAACCTCCCGGAGGAACTGC
TACATCGTTGTGGTAGGCTCGGTCACTATTCCACGTCTCGATGTGCAAAA
ATTTTATTATGTTTAAGTTATTGTTTCGCATGGTGATGACTGTTGCTGGT
GAATAATTCTGTTAGGATTTGATTTCCATTTTGTTTTATAGCAATAAATA
TTTCGTTTATTTTCAAAAAAAA
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protein sequence of SMED30009564-orf-1

>SMED30009564-orf-1 ID=SMED30009564-orf-1|Name=SMED30009564-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=593bp
MNDSKVNIGVKKVPLHLQSSQNRLCIKGAKIVNDDRMFDADVYIEDGIIK
QLGTNLVIPGGVRCVEANGKLLIPGGIDTHTHMEFPFMGTVSSDDFYSGT
RAALAGGTTMIIDFVIGQKGTSLIDSYNQYREKADSKVCCDYGLHVIVSS
YNESVGNEMEKLASEHGINSFKIFMAYKDSLMLEDDEMYEVFKKCKSIGA
LAQVHAENGKLIEKKSLELISKGITGPEGHLYSRPEEVECEATNRAIMLA
DQANCPLYVVHVMSKGAADIISDARRQGKVVFGEPIAAGLGTDGSHYSHS
CWRHAAGYVMSPPLRNDRNTSKHLMQLLASGDLECTGTDHCVFKASQKAL
GKDDFRSIPNGVNGVEDRMSVIWEKGVVTGILDPCKFVAVTSTNAAKIFN
IYPKKGRIDIGSDADLVLWNPDVRRTISASTHYQNVDFNIFEGMHCHGVA
EMVISGGKVVLEDGNLRVAQGTGKFVPTNPFCNYVFNKVKLRDQCHKTLA
NKVERQPYDGPVEDLSKEMTNLNMNFDDDTDSQQNAISSEFVNTKRPLTS
GGGRHMQDSSFALSGAQIDDNLPTRSGIRTRQPPGGTATSLW*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000099neuron
PLANA:0000103central nervous system
PLANA:0002111X2 cell
Vocabulary: INTERPRO
TermDefinition
IPR011778Hydantoinase/dihydroPyrase
IPR006680Amidohydro-rel
IPR011059Metal-dep_hydrolase_composite
IPR032466Metal_Hydrolase
Vocabulary: molecular function
TermDefinition
GO:0016787hydrolase activity
GO:0016810hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
Vocabulary: cellular component
TermDefinition
GO:0005737cytoplasm
GO:0016020membrane
GO:0016021integral component of membrane
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR006680Amidohydrolase-relatedPFAMPF01979Amidohydro_1coord: 72..460
e-value: 6.0E-31
score: 108.0
IPR011059Metal-dependent hydrolase, composite domain superfamilyGENE3DG3DSA:2.30.40.10coord: 24..490
e-value: 1.7E-223
score: 744.3
IPR011059Metal-dependent hydrolase, composite domain superfamilySUPERFAMILYSSF51338Composite domain of metallo-dependent hydrolasescoord: 23..86
IPR011059Metal-dependent hydrolase, composite domain superfamilySUPERFAMILYSSF51338Composite domain of metallo-dependent hydrolasescoord: 385..481
NoneNo IPR availableGENE3DG3DSA:3.20.20.140coord: 75..447
e-value: 1.7E-223
score: 744.3
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 565..592
NoneNo IPR availablePANTHERPTHR11647AMINOHYDROLASEcoord: 18..518
NoneNo IPR availablePANTHERPTHR11647:SF1COLLAPSIN RESPONSE MEDIATOR PROTEINcoord: 18..518
IPR011778Hydantoinase/dihydropyrimidinaseTIGRFAMTIGR02033TIGR02033coord: 25..477
e-value: 2.0E-182
score: 605.1
IPR011778Hydantoinase/dihydropyrimidinaseCDDcd01314D-HYDcoord: 24..473
e-value: 0.0
score: 717.459
IPR032466Metal-dependent hydrolaseSUPERFAMILYSSF51556Metallo-dependent hydrolasescoord: 75..406