Polypeptide N-acetylgalactosaminyltransferase

Query:  306 DSQIKIDWANHDTIDEENARVGPGEQGIGVYLTANENEKAKQLMETNGYNALASDKISVHRSIKDLRINKCKWLKYDNFLPPASIIIPFHNEHWSTLLRTVHSILHRSPDKLVKEIILVDDNSTKEFLGEKLEQYVSEHFTKVRILRTGKREGLIRARLLGANEANGTVLIFIDSHCEVGINWLPPLLQPIRDHYKTISCPFIDVISYNDFSLRPQ-DEGGRGAFDWNFDYKRLPRLSK-DNAHPEKPFYNPIMAGGLFAISKLWFNELGGYDYGLDVWGGEQYELSFKVWMCGGKMVDVPCSRVGHVYRKFNPFAVVGLGNYLARNHKRIAEVWMDDWKQYIYQKHQKVYSSLDPGDLTEQKKLRKALNCTSFDWFMKQIAYDLLEKYPIQKQPENLSQGKIKSEINPHLCFDFNLGNPGDPFRISNCTDVSNE------QNLAFTWEMEIKP----QKRDICLDYPRKGEELTMFSCHGMGGNQKWIYNQNSHQIVHVVSKKCIDYRYNPESLEINIQKCSRKLSQKWILENMNAMI 1886
            D Q   DW + + I  +  RVG GEQG    +T  + E+  Q    NG+N   SDKIS++RS+ D+R   C   +Y   LP  SIIIPFHNE WS+LLRTVHS+L+RSP +LV EI+LVDD S +E L + LE Y++  F  VRILRT KREGLIR R+LGA+ A G V+ F+DSHCE  +NWLPPLL  I  + KTI CP IDVI ++DF    Q  +  RGAFDW   YKR+P   +   A P  PF +P+MAGGLFA+ + WF ELGGYD GL++WGGEQYE+SFKVWMCGG+M D+PCSRVGH+YRK+ P+ V   G  LARN KR+AEVWMD++ +YIYQ+  + Y  L  GD+  QKKLR +LNC SF WFM +IA+DL + YP   +P   + G+I++ +   LC D   G  G P R+  C     E      Q   FTW  +I+P      +  C D       +T++ CH M GNQ W Y ++   + H VS  C+D   +   + +N    S  L+Q+W+ E+ N+ +
Sbjct:   67 DGQKLKDWHDKEAIRRDAQRVGNGEQGRPYPMT--DAERVDQAYRENGFNIYVSDKISLNRSLPDIRHPNCNSKRYLETLPNTSIIIPFHNEGWSSLLRTVHSVLNRSPPELVAEIVLVDDFSDREHLKKPLEDYMA-LFPSVRILRTKKREGLIRTRMLGASVATGDVITFLDSHCEANVNWLPPLLDRIARNRKTIVCPMIDVIDHDDFRYETQAGDAMRGAFDWEMYYKRIPIPPELQKADPSDPFESPVMAGGLFAVDRKWFWELGGYDPGLEIWGGEQYEISFKVWMCGGRMEDIPCSRVGHIYRKYVPYKVPA-GVSLARNLKRVAEVWMDEYAEYIYQRRPE-YRHLSAGDVAVQKKLRSSLNCKSFKWFMTKIAWDLPKFYP-PVEPPAAAWGEIRN-VGTGLCADTKHGALGSPLRLEGCVRGRGEAAWNNMQVFTFTWREDIRPGDPQHTKKFCFDAISHTSPVTLYDCHSMKGNQLWKYRKDK-TLYHPVSGSCMDCSESDHRIFMNTCNPS-SLTQQWLFEHTNSTV 596          

Query:  303 SDSQIKIDWANHDTIDEENARVGPGEQGIGVYLTANENEKAKQLMETNGYNALASDKISVHRSIKDLRINKCKWLKYDNFLPPASIIIPFHNEHWSTLLRTVHSILHRSPDKLVKEIILVDDNSTKEFLGEKLEQYVSEHFTKVRILRTGKREGLIRARLLGANEANGTVLIFIDSHCEVGINWLPPLLQPIRDHYKTISCPFIDVISYNDFSLRPQ-DEGGRGAFDWNFDYKRLPRLSK-DNAHPEKPFYNPIMAGGLFAISKLWFNELGGYDYGLDVWGGEQYELSFKVWMCGGKMVDVPCSRVGHVYRKFNPFAVVGLGNYLARNHKRIAEVWMDDWKQYIYQKHQKVYSSLDPGDLTEQKKLRKALNCTSFDWFMKQIAYDLLEKYPIQKQPENLSQGKIKSEINPHLCFDFNLGNPGDPFRISNCT------DVSNEQNLAFTWEMEIKP----QKRDICLDYPRKGEELTMFSCHGMGGNQKWIYNQNSHQIVHVVSKKCIDYRYNPESLEINIQKCSR-KLSQKWILENMNAMI 1886
            +D   + DW ++++I +E  R G GE G    LT  +++ +      NG+N   S+ I++ RS+ D+R   CK   Y   LP  SIIIPFHNE W++LLRT+HSI++R+P  L+ EIILVDD S +E L +KLE+Y++  F+KVRI+RT KREGLIR RLLGA+ A G VL F+DSHCEV +NWLPPLL  I  ++KTI CP IDVI +N F    Q  +  RGAFDW   YKR+P   +   A P  PF +P+MAGGLFA+ + WF ELGGYD GL++WGGEQYE+SFKVWMCGG+M DVPCSRVGH+YRK+ P+ V   G  LARN KR+AE WMD++ +YIYQ+  + Y  L  GD++ QK+LRK L C  F WFM  +A+D+ + YP   +P   + G+I++ +  +LC D   G  G   R+  C         S+EQ   F W  +I+P      R  C D       +T++ CHGM GNQ W Y ++   + H VS  C+D   NP   +I + +C     +Q+WI E++N  +
Sbjct:   44 TDGLRRKDWHDYESIQKEAMRSGKGEHGKPYPLTEEDHDDSA--YRENGFNIFVSNNIALERSLPDIRHANCKHKMYLERLPNTSIIIPFHNEGWTSLLRTIHSIINRTPGSLIAEIILVDDFSEREHLKDKLEEYMAR-FSKVRIVRTKKREGLIRTRLLGASMARGEVLTFLDSHCEVNVNWLPPLLNQIALNHKTIVCPMIDVIDHNHFGYEAQAGDAMRGAFDWEMYYKRIPIPPELQRADPSDPFESPVMAGGLFAVDRKWFWELGGYDPGLEIWGGEQYEISFKVWMCGGEMFDVPCSRVGHIYRKYVPYKVPS-GTSLARNLKRVAETWMDEFAEYIYQRRPE-YRHLSTGDISAQKELRKQLKCKDFKWFMAAVAWDVPKYYP-PVEPPPAAWGEIRN-VAANLCVDSKHGATGTELRLDICVKDGSERTWSHEQLFTFGWREDIRPGEPLHTRKFCFDAISHNSPVTLYDCHGMKGNQLWGYRKD-RTLFHPVSNSCMD--CNPAEKKIFMARCDPLSETQQWIFEHINMTV 574          

Query:  303 SDSQIKIDWANHDTIDEENARVGPGEQGIGVYLTANENEKAKQLMETNGYNALASDKISVHRSIKDLRINKCKWLKYDNFLPPASIIIPFHNEHWSTLLRTVHSILHRSPDKLVKEIILVDDNSTKEFLGEKLEQYVSEHFTKVRILRTGKREGLIRARLLGANEANGTVLIFIDSHCEVGINWLPPLLQPIRDHYKTISCPFIDVISYNDFSLRPQ-DEGGRGAFDWNFDYKRLPRLSK-DNAHPEKPFYNPIMAGGLFAISKLWFNELGGYDYGLDVWGGEQYELSFKVWMCGGKMVDVPCSRVGHVYRKFNPFAVVGLGNYLARNHKRIAEVWMDDWKQYIYQKHQKVYSSLDPGDLTEQKKLRKALNCTSFDWFMKQIAYDLLEKYPIQKQPENLSQGKIKSEINPHLCFDFNLGNPGDPFRISNCT------DVSNEQNLAFTWEMEIKP----QKRDICLDYPRKGEELTMFSCHGMGGNQKWIYNQNSHQIVHVVSKKCIDYRYNPESLEINIQKCSR-KLSQKWILENMNAMI 1886
            +D   + DW ++++I +E  R G GE G    LT  +++ +      NG+N   S+ I++ RS+ D+R   CK   Y   LP  SIIIPFHNE W++LLRT+HSI++R+P  L+ EIILVDD S +E L +KLE+Y++  F+KVRI+RT KREGLIR RLLGA+ A G VL F+DSHCEV +NWLPPLL  I  ++KTI CP IDVI +N F    Q  +  RGAFDW   YKR+P   +   A P  PF +P+MAGGLFA+ + WF ELGGYD GL++WGGEQYE+SFKVWMCGG+M DVPCSRVGH+YRK+ P+ V   G  LARN KR+AE WMD++ +YIYQ+  + Y  L  GD++ QK+LRK L C  F WFM  +A+D+ + YP   +P   + G+I++ +  +LC D   G  G   R+  C         S+EQ   F W  +I+P      R  C D       +T++ CHGM GNQ W Y ++   + H VS  C+D   NP   +I + +C     +Q+WI E++N  +
Sbjct:   61 TDGLRRKDWHDYESIQKEAMRSGKGEHGKPYPLTEEDHDDSA--YRENGFNIFVSNNIALERSLPDIRHANCKHKMYLERLPNTSIIIPFHNEGWTSLLRTIHSIINRTPGSLIAEIILVDDFSEREHLKDKLEEYMAR-FSKVRIVRTKKREGLIRTRLLGASMARGEVLTFLDSHCEVNVNWLPPLLNQIALNHKTIVCPMIDVIDHNHFGYEAQAGDAMRGAFDWEMYYKRIPIPPELQRADPSDPFESPVMAGGLFAVDRKWFWELGGYDPGLEIWGGEQYEISFKVWMCGGEMFDVPCSRVGHIYRKYVPYKVPS-GTSLARNLKRVAETWMDEFAEYIYQRRPE-YRHLSTGDISAQKELRKQLKCKDFKWFMAAVAWDVPKYYP-PVEPPPAAWGEIRN-VAANLCVDSKHGATGTELRLDICVKDGSERTWSHEQLFTFGWREDIRPGEPLHTRKFCFDAISHNSPVTLYDCHGMKGNQLWGYRKD-RTLFHPVSNSCMD--CNPAEKKIFMARCDPLSETQQWIFEHINMTV 591          

Query:  369 GPGEQGIGVYLTANENEKAKQLMETNGYNALASDKISVHRSIKDLRINKCKWLKYDNFLPPASIIIPFHNEHWSTLLRTVHSILHRSPDKLVKEIILVDDNSTKEFLGEKLEQYVSEHFTKVRILRTGKREGLIRARLLGANEANGTVLIFIDSHCEVGINWLPPLLQPIRDHYKTISCPFIDVISYNDFSLRPQDEGGRGAFDW--NFDYKRLPRLSKDNAHPEK--PFYNPIMAGGLFAISKLWFNELGGYDYGLDVWGGEQYELSFKVWMCGGKMVDVPCSRVGHVYRKFNPFAVV-GLGNYLARNHKRIAEVWMDDWKQYIYQKHQKVYSSLDPGDLTEQKKLRKALNCTSFDWFMKQIAYDLLEKYPIQKQPEN-LSQGKIKSEINPHLCFDFNLGNP-GDPFRISNCTDVSNEQNLAFTWEMEIKPQKRDICLDYPRKGEELTMFSCHGMGGNQKWIYNQNSHQIVHVVSKKCIDYRYNPESLEINIQKCSRKLSQKWILENMN 1877
            GPGE G  V +  ++ EK K+L + N +N +ASD I+++RS+ D+R+  CK   Y + LP  S++I FHNE WSTLLRTV+S+++RSP  L+ E+ILVDD S ++FL   LE YV      V+I+R  +R GLIRARL GA  + G V+ F+D+HCE  + WL PLL  I++  KT+ CP IDVIS + F      +   G F+W  NF +  +P+   D    ++  P   P MAGGLF+I + +F E+G YD G+D+WGGE  E+SF++W CGG +  V CS VGHV+RK  P+    G G+ + +N++R+AEVWMD++K + Y     V   +D GD++ +K LR+ L C  F W+++ I       YP  + P    S G+I++ +  + C D N+G    +   I NC  +   Q  ++T + EI+    D+CLD  R    + M  CH M GNQ W Y+     + HV S +C+D     + +   +Q CS   SQ+W+L NM 
Sbjct:   56 GPGEMGKAVLIPKDDQEKMKELFKINQFNLMASDLIALNRSLPDVRLEGCKTKVYPDELPNTSVVIVFHNEAWSTLLRTVYSVINRSPHYLLSEVILVDDASERDFLKLTLENYVKNLEVPVKIIRMEERSGLIRARLRGAAASKGQVITFLDAHCECTLGWLEPLLARIKEDRKTVVCPIIDVISDDTFEYMAGSDMTYGGFNWKLNFRWYPVPQREMDRRKGDRTLPVRTPTMAGGLFSIDRNYFEEIGTYDAGMDIWGGENLEMSFRIWQCGGSLEIVTCSHVGHVFRKATPYTFPGGTGHVINKNNRRLAEVWMDEFKDFFYIISPGVV-KVDYGDVSVRKTLRENLKCKPFSWYLENI-------YPDSQIPRRYYSLGEIRN-VETNQCLD-NMGRKENEKVGIFNCHGMGGNQVFSYTADKEIRTD--DLCLDVSRLNGPVIMLKCHHMRGNQLWEYDAERLTLRHVNSNQCLDEPSEEDKMVPTMQDCSGSRSQQWLLRNMT 553          

Query:  681 EFLGEKLEQYVSEHFTKVRILRTGKREGLIRARLLGANEANGTVLIFIDSHCEVGINWLPPLLQPIRDHYKTISCPFIDVISYNDFSLRPQ-DEGGRGAFDWNFDYKRLPRLSK-DNAHPEKPFYNPIMAGGLFAISKLWFNELGGYDYGLDVWGGEQYELSFKVWMCGGKMVDVPCSRVGHVYRKFNPFAVVGLGNYLARNHKRIAEVWMDDWKQYIYQKHQKVYSSLDPGDLTEQKKLRKALNCTSFDWFMKQIAYDLLEKYPIQKQPENLSQGKIKSEINPHLCFDFNLGNPGDPFRISNCT------DVSNEQNLAFTWEMEIKP----QKRDICLDYPRKGEELTMFSCHGMGGNQKWIYNQNSHQIVHVVSKKCIDYRYNPESLEINIQKCSR-KLSQKWILENMNAMI 1886
            E L +KLE+Y++  F+KVRI+RT KREGLIR RLLGA+ A G VL F+DSHCEV +NWLPPLL  I  ++KTI CP IDVI +N F    Q  +  RGAFDW   YKR+P   +   A P  PF +P+MAGGLFA+ + WF ELGGYD GL++WGGEQYE+SFKVWMCGG+M DVPCSRVGH+YRK+ P+ V   G  LARN KR+AE WMD++ +YIYQ+  + Y  L  GD++ QK+LRK L C  F WFM  +A+D+ + YP   +P   + G+I++ +  +LC D   G  G   R+  C         S+EQ   F W  +I+P      R  C D       +T++ CHGM GNQ W Y ++   + H VS  C+D   NP   +I + +C     +Q+WI E++N  +
Sbjct:    1 EHLKDKLEEYMAR-FSKVRIVRTKKREGLIRTRLLGASMARGEVLTFLDSHCEVNVNWLPPLLNQIALNHKTIVCPMIDVIDHNHFGYEAQAGDAMRGAFDWEMYYKRIPIPPELQRADPSDPFESPVMAGGLFAVDRKWFWELGGYDPGLEIWGGEQYEISFKVWMCGGEMFDVPCSRVGHIYRKYVPYKVPS-GTSLARNLKRVAETWMDEFAEYIYQRRPE-YRHLSTGDISAQKELRKQLKCKDFKWFMAAVAWDVPKYYP-PVEPPPAAWGEIRN-VAANLCVDSKHGATGTELRLDICVKDGSERTWSHEQLFTFGWREDIRPGEPLHTRKFCFDAISHNSPVTLYDCHGMKGNQLWGYRKD-RTLFHPVSNSCMD--CNPAEKKIFMARCDPLSETQQWIFEHINMTV 407          

Query:  318 KIDWANHDTIDEENARVGPGEQGIGVYLTANEN--EKAKQLMETNGYNALASDKISVHRSIKDLRINKCKWLKYDNFLPPASIIIPFHNEHWSTLLRTVHSILHRSPDKLVKEIILVDDNSTKEFLGEKLEQYVSEHFTK--VRILRTGKREGLIRARLLGANEANGTVLIFIDSHCEVGINWLPPLLQPIRDHYKTISCPFIDVISYNDFSLRPQDEGGRGAFDWNFDYKRLPRLSKDNAHPEKPFYNPIMAGGLFAISKLWFNELGGYDYGLDVWGGEQYELSFKVWMCGGKMVDVPCSRVGHVYR-KFNPFAVVGLGNYLARNHKRIAEVWMDDWKQYIYQKHQKVYSSLDPGDLTEQKKLRKALNCTSFDWFMKQIAYDLLEKYPIQKQPENLSQGKIKSEINPHLCFDFNLGNPGDPFRISNCT----DVSNEQNLAFTWEMEIKPQKRDICLDYPRKGEE--LTMFSCHGMGGNQKWIYNQNSHQIVHVVSKKCIDYRYNPESLEINIQKC-SRKLSQKWILENMN 1877
            KI W +    ++E  R GPGE G  V L  ++   ++A  L + NGYNA  SD IS++RSIKD+R  +CK + Y   LP  S+I PFH EH STLLR+V+S+++RSP +L+KEIILVDD S K  L + LE ++ ++     V++LRT KREGLIR R LGA +A G +LIF+D+H E   NWLPPLL PI + Y+T+ CPF+DVI    + +RPQDEG RG+FDW F+YKRLP   KD   P KPF +P+MAGG FAIS  WF ELGGYD GLD+WGGEQYELSFKVW C G+MVD PCSRV H+YR K+ PF   G+G++++RN+KR+AEVWMDD+K+ +Y KH+    + D GDL   K +R+ L C SFDWFMK+IA+D  + YP   +P+  ++G+I++ +  + C D         F +  CT    D   EQ+L  T   +I+P+ R IC D     ++  + +F CH M GNQ + Y     QI H +S +C+    N +   ++++KC S    QKW  + ++
Sbjct:   79 KIKWEDEAAYEKEKRREGPGEWGKPVKLPEDKEVEKEALSLYKANGYNAYISDMISLNRSIKDIRHKECKNMMYSAKLPTVSVIFPFHEEHNSTLLRSVYSVINRSPPELLKEIILVDDFSEKPALRQPLEDFLKKNKIDHIVKVLRTKKREGLIRGRQLGAQDATGEILIFLDAHSEANYNWLPPLLDPIAEDYRTVVCPFVDVIDCETYEVRPQDEGARGSFDWAFNYKRLPLTKKDRESPTKPFNSPVMAGGYFAISAKWFWELGGYDEGLDIWGGEQYELSFKVWQCHGRMVDAPCSRVAHIYRCKYAPFKNAGMGDFVSRNYKRVAEVWMDDYKETLY-KHRPGVGNADAGDLKLMKGIREKLQCKSFDWFMKEIAFDQDKYYPAV-EPKASAEGEIRN-VGTNFCIDTQFKEQNQRFGLRKCTSDDKDGGGEQDLRLTRWHDIRPKGRKICFDCSTSVDKAPVILFDCHSMKGNQLFKYRVAQKQIYHPISGQCLTADENGKGF-LHMKKCDSSSDLQKWAWQTVD 606          

Query:  318 KIDWANHDTIDEENARVGPGEQGIGVYLTANEN--EKAKQLMETNGYNALASDKISVHRSIKDLRINKCKWLKYDNFLPPASIIIPFHNEHWSTLLRTVHSILHRSPDKLVKEIILVDDNSTKEFLGEKLEQYVSEHFTK--VRILRTGKREGLIRARLLGANEANGTVLIFIDSHCEVGINWLPPLLQPIRDHYKTISCPFIDVISYNDFSLRPQDEGGRGAFDWNFDYKRLPRLSKDNAHPEKPFYNPIMAGGLFAISKLWFNELGGYDYGLDVWGGEQYELSFKVWMCGGKMVDVPCSRVGHVYR-KFNPFAVVGLGNYLARNHKRIAEVWMDDWKQYIYQKHQKVYSSLDPGDLTEQKKLRKALNCTSFDWFMKQIAYDLLEKYPIQKQPENLSQGKIKSEINPHLCFDFNLGNPGDPFRISNCT----DVSNEQNLAFTWEMEIKPQKRDICLDYPRKGEE--LTMFSCHGMGGNQKWIYNQNSHQIVHVVSKKCIDYRYNPESLEINIQKC-SRKLSQKWILENMN 1877
            KI W +    ++E  R GPGE G  V L  ++   ++A  L + NGYNA  SD IS++RSIKD+R  +CK + Y   LP  S+I PFH EH STLLR+V+S+++RSP +L+KEIILVDD S K  L + LE ++ ++     V++LRT KREGLIR R LGA +A G +LIF+D+H E   NWLPPLL PI + Y+T+ CPF+DVI    + +RPQDEG RG+FDW F+YKRLP   KD   P KPF +P+MAGG FAIS  WF ELGGYD GLD+WGGEQYELSFKVW C G+MVD PCSRV H+YR K+ PF   G+G++++RN+KR+AEVWMDD+K+ +Y KH+    + D GDL   K +R+ L C SFDWFMK+IA+D  + YP   +P+  ++G+I++ +  + C D         F +  CT    D   EQ+L  T   +I+P+ R IC D     ++  + +F CH M GNQ + Y     QI H +S +C+    N +   ++++KC S    QKW  + ++
Sbjct:  160 KIKWEDEAAYEKEKRREGPGEWGKPVKLPEDKEVEKEALSLYKANGYNAYISDMISLNRSIKDIRHKECKNMMYSAKLPTVSVIFPFHEEHNSTLLRSVYSVINRSPPELLKEIILVDDFSEKPALRQPLEDFLKKNKIDHIVKVLRTKKREGLIRGRQLGAQDATGEILIFLDAHSEANYNWLPPLLDPIAEDYRTVVCPFVDVIDCETYEVRPQDEGARGSFDWAFNYKRLPLTKKDRESPTKPFNSPVMAGGYFAISAKWFWELGGYDEGLDIWGGEQYELSFKVWQCHGRMVDAPCSRVAHIYRCKYAPFKNAGMGDFVSRNYKRVAEVWMDDYKETLY-KHRPGVGNADAGDLKLMKGIREKLQCKSFDWFMKEIAFDQDKYYPAV-EPKASAEGEIRN-VGTNFCIDTQFKEQNQRFGLRKCTSDDKDGGGEQDLRLTRWHDIRPKGRKICFDCSTSVDKAPVILFDCHSMKGNQLFKYRVAQKQIYHPISGQCLTADENGKGF-LHMKKCDSSSDLQKWAWQTVD 687          

Query:  336 HDTIDEENARVGPGEQGIGVY-----LTANENEKAKQLMETNGYNALASDKISVHRSIKDLRINKCKWLKYDNFLPPASIIIPFHNEHWSTLLRTVHSILHRSPDKLVKEIILVDDNSTKEFLGEKLEQYVSEHFTKVRILRTGKREGLIRARLLGANEANGTVLIFIDSHCEVGINWLPPLLQPIRDHYKTISCPFIDVISYNDFSLRPQDE--GGRGAFDWN--FDYKRLP-RLSKDNAHPEKPFYNPIMAGGLFAISKLWFNELGGYDYGLDVWGGEQYELSFKVWMCGGKMVDVPCSRVGHVYRKFNPFAVVGLGNYLARNHKRIAEVWMDDWKQYIYQKHQKVYSSLDPGDLTEQKKLRKALNCTSFDWFMKQIAYDLLEKYPIQKQP-ENLSQGKIK-SEINPHLCFDFNLGN--PGDPFRISNCTDVSNEQNLAFTWEMEIKPQKRDICLDYPRKGEELTMFSCHGMGGNQKWIYNQNSHQIVHVVSKKCIDYRYNPESLEI 1820
            +D I ++      GE G  V      L+  E  K  + M  N +N  ASD ISVHR++      +CK  KY+  LP  S+II FHNE WS LLRTVHS+L R+PD L++E++LVDD S  +     LE+Y+S+   KV+ILR  KREGLIRARL GA  A G VL ++DSHCE    W+ PLL  I+    T+ CP IDVI  N F            G FDW   F++  +P R  K+   P  P  +P MAGGLF+I K +F +LG YD G D+WGGE  ELSFK+WMCGG +  VPCS VGHV+RK +P+      N L RN  R+AEVW+DD+K Y Y++        D GD++ +KKLR+ L C SF W++  I       YP    P E++++G+++ S + P  C D  +G      P     C      Q    + + EI+  + + C+DY   G ++ +F CHGM GNQ+W YN ++ ++ H VS+KC+    +   LE+
Sbjct:  100 NDPIYKKGDAAQAGELGKAVVVDKTKLSTEEKAKYDKGMLNNAFNQYASDMISVHRTLPTNIDAECKTEKYNENLPRTSVIICFHNEAWSVLLRTVHSVLERTPDHLLEEVVLVDDFSDMDHTKRPLEEYMSQFGGKVKILRMEKREGLIRARLRGAAVATGEVLTYLDSHCECMEGWMEPLLDRIKRDPTTVVCPVIDVIDDNTFEYHHSKAYFTSVGGFDWGLQFNWHSIPERDRKNRTRPIDPVRSPTMAGGLFSIDKKYFEKLGTYDPGFDIWGGENLELSFKIWMCGGTLEIVPCSHVGHVFRKRSPYKWRTGVNVLKRNSIRLAEVWLDDYKTYYYERINNQLG--DFGDISSRKKLREDLGCKSFKWYLDNI-------YPELFVPGESVAKGEVRNSAVQPARCLDCMVGRHEKNRPVGTYQCHGQGGNQYWMLSKDGEIR--RDESCVDY--AGSDVMVFPCHGMKGNQEWRYNHDTGRLQHAVSQKCLGMTKDGAKLEM 595          

Query:  336 HDTIDEENARVGPGEQGIGVY-----LTANENEKAKQLMETNGYNALASDKISVHRSIKDLRINKCKWLKYDNFLPPASIIIPFHNEHWSTLLRTVHSILHRSPDKLVKEIILVDDNSTKEFLGEKLEQYVSEHFTKVRILRTGKREGLIRARLLGANEANGTVLIFIDSHCEVGINWLPPLLQPIRDHYKTISCPFIDVISYNDFSLRPQDE--GGRGAFDWN--FDYKRLP-RLSKDNAHPEKPFYNPIMAGGLFAISKLWFNELGGYDYGLDVWGGEQYELSFKVWMCGGKMVDVPCSRVGHVYRKFNPFAVVGLGNYLARNHKRIAEVWMDDWKQYIYQKHQKVYSSLDPGDLTEQKKLRKALNCTSFDWFMKQIAYDLLEKYPIQKQP-ENLSQGKIK-SEINPHLCFDFNLGN--PGDPFRISNCTDVSNEQNLAFTWEMEIKPQKRDICLDYPRKGEELTMFSCHGMGGNQKWIYNQNSHQIVHVVSKKCIDYRYNPESLEI 1820
            +D I ++      GE G  V      L+  E  K  + M  N +N  ASD ISVHR++      +CK  KY+  LP  S+II FHNE WS LLRTVHS+L R+PD L++E++LVDD S  +     LE+Y+S+   KV+ILR  KREGLIRARL GA  A G VL ++DSHCE    W+ PLL  I+    T+ CP IDVI  N F            G FDW   F++  +P R  K+   P  P  +P MAGGLF+I K +F +LG YD G D+WGGE  ELSFK+WMCGG +  VPCS VGHV+RK +P+      N L RN  R+AEVW+DD+K Y Y++        D GD++ +KKLR+ L C SF W++  I       YP    P E++++G+++ S + P  C D  +G      P     C      Q    + + EI+  + + C+DY   G ++ +F CHGM GNQ+W YN ++ ++ H VS+KC+    +   LE+
Sbjct:  100 NDPIYKKGDAAQAGELGKAVVVDKTKLSTEEKAKYDKGMLNNAFNQYASDMISVHRTLPTNIDAECKTEKYNENLPRTSVIICFHNEAWSVLLRTVHSVLERTPDHLLEEVVLVDDFSDMDHTKRPLEEYMSQFGGKVKILRMEKREGLIRARLRGAAVATGEVLTYLDSHCECMEGWMEPLLDRIKRDPTTVVCPVIDVIDDNTFEYHHSKAYFTSVGGFDWGLQFNWHSIPERDRKNRTRPIDPVRSPTMAGGLFSIDKKYFEKLGTYDPGFDIWGGENLELSFKIWMCGGTLEIVPCSHVGHVFRKRSPYKWRTGVNVLKRNSIRLAEVWLDDYKTYYYERINNQLG--DFGDISSRKKLREDLGCKSFKWYLDNI-------YPELFVPGESVAKGEVRNSAVQPARCLDCMVGRHEKNRPVGTYQCHGQGGNQYWMLSKDGEIR--RDESCVDY--AGSDVMVFPCHGMKGNQEWRYNHDTGRLQHAVSQKCLGMTKDGAKLEM 595          

Query:  336 HDTIDEENARVGPGEQGIGVY-----LTANENEKAKQLMETNGYNALASDKISVHRSIKDLRINKCKWLKYDNFLPPASIIIPFHNEHWSTLLRTVHSILHRSPDKLVKEIILVDDNSTKEFLGEKLEQYVSEHFTKVRILRTGKREGLIRARLLGANEANGTVLIFIDSHCEVGINWLPPLLQPIRDHYKTISCPFIDVISYNDFSLRPQDE--GGRGAFDWN--FDYKRLP-RLSKDNAHPEKPFYNPIMAGGLFAISKLWFNELGGYDYGLDVWGGEQYELSFKVWMCGGKMVDVPCSRVGHVYRKFNPFAVVGLGNYLARNHKRIAEVWMDDWKQYIYQKHQKVYSSLDPGDLTEQKKLRKALNCTSFDWFMKQIAYDLLEKYPIQKQP-ENLSQGKIK-SEINPHLCFDFNLGN--PGDPFRISNCTDVSNEQNLAFTWEMEIKPQKRDICLDYPRKGEELTMFSCHGMGGNQKWIYNQNSHQIVHVVSKKCIDYRYNPESLEI 1820
            +D I ++      GE G  V      L+  E  K  + M  N +N  ASD ISVHR++      +CK  KY+  LP  S+II FHNE WS LLRTVHS+L R+PD L++E++LVDD S  +     LE+Y+S+   KV+ILR  KREGLIRARL GA  A G VL ++DSHCE    W+ PLL  I+    T+ CP IDVI  N F            G FDW   F++  +P R  K+   P  P  +P MAGGLF+I K +F +LG YD G D+WGGE  ELSFK+WMCGG +  VPCS VGHV+RK +P+      N L RN  R+AEVW+DD+K Y Y++        D GD++ +KKLR+ L C SF W++  I       YP    P E++++G+++ S + P  C D  +G      P     C      Q    + + EI+  + + C+DY   G ++ +F CHGM GNQ+W YN ++ ++ H VS+KC+    +   LE+
Sbjct:  100 NDPIYKKGDAAQAGELGKAVVVDKTKLSTEEKAKYDKGMLNNAFNQYASDMISVHRTLPTNIDAECKTEKYNENLPRTSVIICFHNEAWSVLLRTVHSVLERTPDHLLEEVVLVDDFSDMDHTKRPLEEYMSQFGGKVKILRMEKREGLIRARLRGAAVATGEVLTYLDSHCECMEGWMEPLLDRIKRDPTTVVCPVIDVIDDNTFEYHHSKAYFTSVGGFDWGLQFNWHSIPERDRKNRTRPIDPVRSPTMAGGLFSIDKKYFEKLGTYDPGFDIWGGENLELSFKIWMCGGTLEIVPCSHVGHVFRKRSPYKWRTGVNVLKRNSIRLAEVWLDDYKTYYYERINNQLG--DFGDISSRKKLREDLGCKSFKWYLDNI-------YPELFVPGESVAKGEVRNSAVQPARCLDCMVGRHEKNRPVGTYQCHGQGGNQYWMLSKDGEIR--RDESCVDY--AGSDVMVFPCHGMKGNQEWRYNHDTGRLQHAVSQKCLGMTKDGAKLEM 595          

Query:  297 VSSDSQIKIDWANHDTIDEENARVGPGEQGIGVYLT-ANENEKAKQLMETNGYNALASDKISVHRSIKDLRINKCKWLKYDNFLPPASIIIPFHNEHWSTLLRTVHSILHRSPDKLVKEIILVDDNSTKEFLGEKLEQYVSEHFTKVRILRTGKREGLIRARLLGANEANGTVLIFIDSHCEVGINWLPPLLQPIRDHYKTISCPFIDVISYNDFSLRPQDEGGRGAFDWNFDYKRLPRLSKDNAHPEKPFYNPIMAGGLFAISKLWFNELGGYDYGLDVWGGEQYELSFKVWMCGGKMVDVPCSRVGHVYR-KFNPFAVVGLGNYLARNHKRIAEVWMDDWKQYIYQKHQKVYSSLDPGDLTEQKKLRKALNCTSFDWFMKQIAYDLLEKYPIQKQPENLSQGKIKSEINPHLCFDFNLGNPGDPFRISNCTD-VSNEQNLAF---TWEMEIKPQKRDICLDYP--RKGEELTMFSCHGMGGNQKWIYNQNSHQIVH-VVSKKCIDYRYNPESLEINIQKC-SRKLSQKWILENMNAMIANHLWKEIKL 1916
              +D+ +K DW ++  ++++  RVG GE G    L   ++ +  K++   NG+NAL SD ISV+RS+ D+R   C+  +Y   LP  S+II F+NE+ S L+R+VHS+++RSP +L+KEIILVDD+S +E+LG++LE Y++EHF  VR++R  +R GLI AR  GA  A   VLIF+DSH E   NWLPPLL+PI  + +T  CPFIDVI + +F  R QDEG RGAFDW F YKRLP L +D  HP  PF +PIMAGGLFAIS+ +F ELGGYD GLD+WGGEQYELSFK+WMCGG+M D PCSR+GH+YR   N       G+YL +N+KR+AEVWMD++K Y+Y     +Y S+DPGDLTEQK +R  LNC SF WFM+++A+DL++ YP    P + + G +++  N +LC D       +   +  C D +   Q   F   +W+ +++ +++  CLD         + ++ CH  GGNQ W Y+    Q+ H    ++C++    P S E+   KC +    Q+W   + N    ++  +++ L
Sbjct:  118 APADASVKKDWHDYTFMEKDAKRVGLGEGGKASTLDDESQRDLEKRMSLENGFNALLSDSISVNRSVPDIRHPLCRKKEYVAKLPTVSVIIIFYNEYLSVLMRSVHSLINRSPPELMKEIILVDDHSDREYLGKELETYIAEHFKWVRVVRLPRRTGLIGARAAGARNATAEVLIFLDSHVEANYNWLPPLLEPIALNKRTAVCPFIDVIDHTNFHYRAQDEGARGAFDWEFFYKRLPLLPEDLKHPADPFKSPIMAGGLFAISREFFWELGGYDEGLDIWGGEQYELSFKIWMCGGEMYDAPCSRIGHIYRGPRNHQPSPRKGDYLHKNYKRVAEVWMDEYKNYLYSHGDGLYESVDPGDLTEQKAIRTKLNCKSFKWFMEEVAFDLMKTYP-PVDPPSYAMGALQNVGNQNLCLDTLGRKKHNKMGMYACADNIKTPQRTQFWELSWKRDLRLRRKKECLDVQIWDANAPVWLWDCHSQGGNQYWYYDYRHKQLKHGTEGRRCLELL--PFSQEVVANKCDTDNRFQQWNFGSFNKTALDNYSQDLVL 664          

Query:  297 VSSDSQIKIDWANHDTIDEENARVGPGEQGIGVYLT-ANENEKAKQLMETNGYNALASDKISVHRSIKDLRINKCKWLKYDNFLPPASIIIPFHNEHWSTLLRTVHSILHRSPDKLVKEIILVDDNSTKEFLGEKLEQYVSEHFTKVRILRTGKREGLIRARLLGANEANGTVLIFIDSHCEVGINWLPPLLQPIRDHYKTISCPFIDVISYNDFSLRPQDEGGRGAFDWNFDYKRLPRLSKDNAHPEKPFYNPIMAGGLFAISKLWFNELGGYDYGLDVWGGEQYELSFKVWMCGGKMVDVPCSRVGHVYR-KFNPFAVVGLGNYLARNHKRIAEVWMDDWKQYIYQKHQKVYSSLDPGDLTEQKKLRKALNCTSFDWFMKQIAYDLLEKYPIQKQPENLSQGKIKSEINPHLCFDFNLGNPGDPFRISNCTD-VSNEQNLAF---TWEMEIKPQKRDICLDYP--RKGEELTMFSCHGMGGNQKWIYNQNSHQIVH-VVSKKCIDYRYNPESLEINIQKC-SRKLSQKWILENMNAMIANHLWKEIKL 1916
              +D+ +K DW ++  ++++  RVG GE G    L   ++ +  K++   NG+NAL SD ISV+RS+ D+R   C+  +Y   LP  S+II F+NE+ S L+R+VHS+++RSP +L+KEIILVDD+S +E+LG++LE Y++EHF  VR++R  +R GLI AR  GA  A   VLIF+DSH E   NWLPPLL+PI  + +T  CPFIDVI + +F  R QDEG RGAFDW F YKRLP L +D  HP  PF +PIMAGGLFAIS+ +F ELGGYD GLD+WGGEQYELSFK+WMCGG+M D PCSR+GH+YR   N       G+YL +N+KR+AEVWMD++K Y+Y     +Y S+DPGDLTEQK +R  LNC SF WFM+++A+DL++ YP    P + + G +++  N +LC D       +   +  C D +   Q   F   +W+ +++ +++  CLD         + ++ CH  GGNQ W Y+    Q+ H    ++C++    P S E+   KC +    Q+W   + N    ++  +++ L
Sbjct:  118 APADASVKKDWHDYTFMEKDAKRVGLGEGGKASTLDDESQRDLEKRMSLENGFNALLSDSISVNRSVPDIRHPLCRKKEYVAKLPTVSVIIIFYNEYLSVLMRSVHSLINRSPPELMKEIILVDDHSDREYLGKELETYIAEHFKWVRVVRLPRRTGLIGARAAGARNATAEVLIFLDSHVEANYNWLPPLLEPIALNKRTAVCPFIDVIDHTNFHYRAQDEGARGAFDWEFFYKRLPLLPEDLKHPADPFKSPIMAGGLFAISREFFWELGGYDEGLDIWGGEQYELSFKIWMCGGEMYDAPCSRIGHIYRGPRNHQPSPRKGDYLHKNYKRVAEVWMDEYKNYLYSHGDGLYESVDPGDLTEQKAIRTKLNCKSFKWFMEEVAFDLMKTYP-PVDPPSYAMGALQNVGNQNLCLDTLGRKKHNKMGMYACADNIKTPQRTQFWELSWKRDLRLRRKKECLDVQIWDANAPVWLWDCHSQGGNQYWYYDYRHKQLKHGTEGRRCLELL--PFSQEVVANKCDTDNRFQQWNFGSFNKTALDNYSQDLVL 664          

Query:  297 VSSDSQIKIDWANHDTIDEENARVGPGEQGIGVYLT-ANENEKAKQLMETNGYNALASDKISVHRSIKDLRINKCKWLKYDNFLPPASIIIPFHNEHWSTLLRTVHSILHRSPDKLVKEIILVDDNSTKEFLGEKLEQYVSEHFTKVRILRTGKREGLIRARLLGANEANGTVLIFIDSHCEVGINWLPPLLQPIRDHYKTISCPFIDVISYNDFSLRPQDEGGRGAFDWNFDYKRLPRLSKDNAHPEKPFYNPIMAGGLFAISKLWFNELGGYDYGLDVWGGEQYELSFKVWMCGGKMVDVPCSRVGHVYR-KFNPFAVVGLGNYLARNHKRIAEVWMDDWKQYIYQKHQKVYSSLDPGDLTEQKKLRKALNCTSFDWFMKQIAYDLLEKYPIQKQPENLSQGKIKSEINPHLCFDFNLGNPGDPFRISNCTD-VSNEQNLAF---TWEMEIKPQKRDICLDYP--RKGEELTMFSCHGMGGNQKWIYNQNSHQIVH-VVSKKCIDYRYNPESLEINIQKC-SRKLSQKWILENMNAMIANHLWKEIKL 1916
              +D+ +K DW ++  ++++  RVG GE G    L   ++ +  K++   NG+NAL SD ISV+RS+ D+R   C+  +Y   LP  S+II F+NE+ S L+R+VHS+++RSP +L+KEIILVDD+S +E+LG++LE Y++EHF  VR++R  +R GLI AR  GA  A   VLIF+DSH E   NWLPPLL+PI  + +T  CPFIDVI + +F  R QDEG RGAFDW F YKRLP L +D  HP  PF +PIMAGGLFAIS+ +F ELGGYD GLD+WGGEQYELSFK+WMCGG+M D PCSR+GH+YR   N       G+YL +N+KR+AEVWMD++K Y+Y     +Y S+DPGDLTEQK +R  LNC SF WFM+++A+DL++ YP    P + + G +++  N +LC D       +   +  C D +   Q   F   +W+ +++ +++  CLD         + ++ CH  GGNQ W Y+    Q+ H    ++C++    P S E+   KC +    Q+W   + N    ++  +++ L
Sbjct:  118 APADASVKKDWHDYTFMEKDAKRVGLGEGGKASTLDDESQRDLEKRMSLENGFNALLSDSISVNRSVPDIRHPLCRKKEYVAKLPTVSVIIIFYNEYLSVLMRSVHSLINRSPPELMKEIILVDDHSDREYLGKELETYIAEHFKWVRVVRLPRRTGLIGARAAGARNATAEVLIFLDSHVEANYNWLPPLLEPIALNKRTAVCPFIDVIDHTNFHYRAQDEGARGAFDWEFFYKRLPLLPEDLKHPADPFKSPIMAGGLFAISREFFWELGGYDEGLDIWGGEQYELSFKIWMCGGEMYDAPCSRIGHIYRGPRNHQPSPRKGDYLHKNYKRVAEVWMDEYKNYLYSHGDGLYESVDPGDLTEQKAIRTKLNCKSFKWFMEEVAFDLMKTYP-PVDPPSYAMGALQNVGNQNLCLDTLGRKKHNKMGMYACADNIKTPQRTQFWELSWKRDLRLRRKKECLDVQIWDANAPVWLWDCHSQGGNQYWYYDYRHKQLKHGTEGRRCLELL--PFSQEVVANKCDTDNRFQQWNFGSFNKTALDNYSQDLVL 664          

Query:  324 DWANHDTIDEENARVGPGEQGIGVYL-TANENEKAKQLMETNGYNALASDKISVHRSIKDLRINKCKWLKYDNFLPPASIIIPFHNEHWSTLLRTVHSILHRSPDKLVKEIILVDDNSTKEFLGEKLEQYVSEHFTK-VRILRTGKREGLIRARLLGANEANGTVLIFIDSHCEVGINWLPPLLQPIRDHYKTISCPFIDVISYNDFS-LRPQDEGGRGAFDWNFDYKRLPRLSKDNAHPEKPFYNPIMAGGLFAISKLWFNELGGYDYGLDVWGGEQYELSFKVWMCGGKMVDVPCSRVGHVYR-KFNPFAVVGLGNYLARNHKRIAEVWMDDWKQYIYQKHQKVYSSLDPGDLTEQKKLRKALNCTSFDWFMKQIAYDLLEKYPIQKQPENLSQGKIKSEINPHLCFDFNLG-NPGDPFRISNCTDVSNEQNLAFTWEMEIKPQKR-----DICLDYPRKGEELT--MFSCHGMGGNQKWIYNQNSHQIVHVV-SKKCID 1790
            DW ++  ++ +  R G GE G+ V +   +E +  K+  E NG+N L SD+ISV+RS+ DLR+  CK  KY   LP  S+I  F NEH++TLLR+++S+++R+P +L+K+I+LVDD S  + L + L+ YV +HF   V I+R  +R+GLI AR+ GA  A G V++F DSH EV  NWLPPL++PI  + K  +CP +D IS+ DFS      +G RG FDW   YK+LP L +D      P+ +P+M GGLFAI+  +F +LGGYD  LD+WGGEQYELSFK+WMCGG ++DVPCSRV H++R    P       N++A+NHKR+AEVWMD++KQY+Y++  K Y +LD GDLT Q+ +R+ L C SF WFM ++A D L K+P   +P + + G I++  NP  C D N+G +  +   + +C D          WE+ I    R      +CLD        T  M+SCH  GGNQ W Y++ + ++VH   +K+C++
Sbjct:  103 DWHDYAAMEADRKRSGFGEHGVAVKIENPDEKQLEKEHYEMNGFNGLISDRISVNRSVPDLRLEACKTRKYLAKLPNISVIFIFFNEHFNTLLRSIYSVINRTPPELLKQIVLVDDGSEWDVLKQPLDDYVQQHFPHLVTIVRNPERQGLIGARIAGAKVAVGQVMVFFDSHIEVNYNWLPPLIEPIAINPKISTCPMVDTISHEDFSYFSGNKDGARGGFDWKMLYKQLPVLPEDALDKSMPYRSPVMMGGLFAINTDFFWDLGGYDDQLDIWGGEQYELSFKIWMCGGMLLDVPCSRVAHIFRGPMKPRGNPRGHNFVAKNHKRVAEVWMDEYKQYVYKRDPKTYDNLDAGDLTRQRGVRERLKCKSFHWFMTEVAPDFLVKFP-PVEPPSYAAGIIQNVANPVYCLD-NMGKSTEEAVGMFSCADNRTHPQPNQFWELSIFRDLRMKGFDSVCLDVHEGPPNATVWMWSCHSQGGNQFWYYDRQTQRLVHGENNKRCLE 602          

Query:  324 DWANHDTIDEENARVGPGEQGIGVYL-TANENEKAKQLMETNGYNALASDKISVHRSIKDLRINKCKWLKYDNFLPPASIIIPFHNEHWSTLLRTVHSILHRSPDKLVKEIILVDDNSTKEFLGEKLEQYVSEHFTK-VRILRTGKREGLIRARLLGANEANGTVLIFIDSHCEVGINWLPPLLQPIRDHYKTISCPFIDVISYNDFS-LRPQDEGGRGAFDWNFDYKRLPRLSKDNAHPEKPFYNPIMAGGLFAISKLWFNELGGYDYGLDVWGGEQYELSFKVWMCGGKMVDVPCSRVGHVYR-KFNPFAVVGLGNYLARNHKRIAEVWMDDWKQYIYQKHQKVYSSLDPGDLTEQKKLRKALNCTSFDWFMKQIAYDLLEKYPIQKQPENLSQGKIKSEINPHLCFDFNLG-NPGDPFRISNCTDVSNEQNLAFTWEMEIKPQKR-----DICLDYPRKGEELT--MFSCHGMGGNQKWIYNQNSHQIVHVV-SKKCID 1790
            DW ++  ++ +  R G GE G+ V +   +E +  K+  E NG+N L SD+ISV+RS+ DLR+  CK  KY   LP  S+I  F NEH++TLLR+++S+++R+P +L+K+I+LVDD S  + L + L+ YV +HF   V I+R  +R+GLI AR+ GA  A G V++F DSH EV  NWLPPL++PI  + K  +CP +D IS+ DFS      +G RG FDW   YK+LP L +D      P+ +P+M GGLFAI+  +F +LGGYD  LD+WGGEQYELSFK+WMCGG ++DVPCSRV H++R    P       N++A+NHKR+AEVWMD++KQY+Y++  K Y +LD GDLT Q+ +R+ L C SF WFM ++A D L K+P   +P + + G I++  NP  C D N+G +  +   + +C D          WE+ I    R      +CLD        T  M+SCH  GGNQ W Y++ + ++VH   +K+C++
Sbjct:  103 DWHDYAAMEADRKRSGFGEHGVAVKIENPDEKQLEKEHYEMNGFNGLISDRISVNRSVPDLRLEACKTRKYLAKLPNISVIFIFFNEHFNTLLRSIYSVINRTPPELLKQIVLVDDGSEWDVLKQPLDDYVQQHFPHLVTIVRNPERQGLIGARIAGAKVAVGQVMVFFDSHIEVNYNWLPPLIEPIAINPKISTCPMVDTISHEDFSYFSGNKDGARGGFDWKMLYKQLPVLPEDALDKSMPYRSPVMMGGLFAINTDFFWDLGGYDDQLDIWGGEQYELSFKIWMCGGMLLDVPCSRVAHIFRGPMKPRGNPRGHNFVAKNHKRVAEVWMDEYKQYVYKRDPKTYDNLDAGDLTRQRGVRERLKCKSFHWFMTEVAPDFLVKFP-PVEPPSYAAGIIQNVANPVYCLD-NMGKSTEEAVGMFSCADNRTHPQPNQFWELSIFRDLRMKGFDSVCLDVHEGPPNATVWMWSCHSQGGNQFWYYDRQTQRLVHGENNKRCLE 602          

Query:  303 SDSQIKIDWANHDTIDEENARVGPGEQGIGVYLTANENEKAKQLMETNGYNALASDKISVHRSIKDLRINKCKWLKYDNFLPPASIIIPFHNEHWSTLLRTVHSILHRSPDKLVKEIILVDDNSTKEFLGEKLEQYVSEHFTKVRILRTGKREGLIRARLLGANEANGTVLIFIDSHCEVGINWLPPLLQPIRDHYKTISCPFIDVISYNDFSLRPQ-DEGGRGAFDWNFDYKRLPRLSK-DNAHPEKPFYNPIMAGGLFAISKLWFNELGGYDYGLDVWGGEQYELSFKVWMCGGKMVDVPCSRVGHVYRKFNPFAVVGLGNYLARNHKRIAEVWMDDWKQYIYQKHQKVYSSLDPGDLTEQKKLRKALNCTSFDWFMKQIAYDLLEKYPIQKQPENLSQGKIKSEINPHLCFDFNLGNPGDPFRISNCTDV------SNEQNLAFTWEMEIKP----QKRDICLDYPRKGEELTMFSCHGMGGNQKWIYNQNSHQIVHVVSKKCIDYRYNPESLEINIQKCSRKL-SQKWILENMNAMIAN 1892
            +D   + DW ++++I ++  RVG GE G    L   E+E    + + NG+N   S+ I++ RS+ D+R   CK   Y   LP  SIIIPFHNE WS+LLRT+HSI +R+PD L+ EIILVDD S +E L   L +Y+S  F KVRI+RT KREGLIR RLLGA+ A G VL F+DSHCE  INWLPPLL  I  + KTI CP IDVI +N F    Q  +  RGAFDW   YKR+P   +     P  P+ +P+MAGGLFA+++ WF ELGGYD GL++WGGEQ+E+SFKVWMCGG M DVPCSRVGH+YRK+ P+ V   G  LARN KR+AE WMD++ +YIYQ+  + Y  L  GDLT QK+LRK L C  F W+M  +A+DL + YP   +P   + G+I++  +  LC D   G+ G   R+ NC         ++EQ   F W  +I+P      R  C D   +   +T++ CHGM GNQ W Y ++   + H+VS  C+D   +P    I + KC  K  +Q+WI + +NA + +
Sbjct:   60 TDGLRRRDWHDYESIRKDGQRVGKGEHGKPYPLV--EDECDDSVYKENGFNIYVSNNIALDRSLPDIRHPNCKQKLYLENLPNTSIIIPFHNEGWSSLLRTLHSISNRTPDHLIAEIILVDDYSDREHLKAHLAEYMSR-FPKVRIVRTKKREGLIRTRLLGASVARGEVLTFLDSHCEANINWLPPLLDQIAQNPKTIVCPMIDVIDHNHFGYEAQAGDAMRGAFDWEMYYKRIPIPPELQGPDPSDPYQSPVMAGGLFAVNRQWFWELGGYDTGLEIWGGEQFEISFKVWMCGGSMYDVPCSRVGHIYRKYVPYKVPS-GTSLARNLKRVAETWMDEYTEYIYQRRPE-YRHLSTGDLTAQKELRKHLKCKDFKWYMNTVAWDLPKYYP-PVEPLPAAWGEIRNAAS-GLCVDSKHGSTGTELRLDNCLKEGAERTWAHEQIFTFGWREDIRPGDPLHTRKFCFDAISQNSPITLYDCHGMKGNQHWSYRKDK-SLYHLVSSGCMD--CSPNDKRIFMNKCDPKSETQQWIFQKVNATVLD 592          

Query:  303 SDSQIKIDWANHDTIDEENARVGPGEQGIGVYLTANENEKAKQLMETNGYNALASDKISVHRSIKDLRINKCKWLKYDNFLPPASIIIPFHNEHWSTLLRTVHSILHRSPDKLVKEIILVDDNSTKEFLGEKLEQYVSEHFTKVRILRTGKREGLIRARLLGANEANGTVLIFIDSHCEVGINWLPPLLQPIRDHYKTISCPFIDVISYNDFSLRPQ-DEGGRGAFDWNFDYKRLPRLSK-DNAHPEKPFYNPIMAGGLFAISKLWFNELGGYDYGLDVWGGEQYELSFKVWMCGGKMVDVPCSRVGHVYRKFNPFAVVGLGNYLARNHKRIAEVWMDDWKQYIYQKHQKVYSSLDPGDLTEQKKLRKALNCTSFDWFMKQIAYDLLEKYPIQKQPENLSQGKIKSEINPHLCFDFNLGNPGDPFRISNCTDV------SNEQNLAFTWEMEIKP----QKRDICLDYPRKGEELTMFSCHGMGGNQKWIYNQNSHQIVHVVSKKCIDYRYNPESLEINIQKCSRKL-SQKWILENMNAMIAN 1892
            +D   + DW ++++I ++  RVG GE G    L   E+E    + + NG+N   S+ I++ RS+ D+R   CK   Y   LP  SIIIPFHNE WS+LLRT+HSI +R+PD L+ EIILVDD S +E L   L +Y+S  F KVRI+RT KREGLIR RLLGA+ A G VL F+DSHCE  INWLPPLL  I  + KTI CP IDVI +N F    Q  +  RGAFDW   YKR+P   +     P  P+ +P+MAGGLFA+++ WF ELGGYD GL++WGGEQ+E+SFKVWMCGG M DVPCSRVGH+YRK+ P+ V   G  LARN KR+AE WMD++ +YIYQ+  + Y  L  GDLT QK+LRK L C  F W+M  +A+DL + YP   +P   + G+I++  +  LC D   G+ G   R+ NC         ++EQ   F W  +I+P      R  C D   +   +T++ CHGM GNQ W Y ++   + H+VS  C+D   +P    I + KC  K  +Q+WI + +NA + +
Sbjct:   60 TDGLRRRDWHDYESIRKDGQRVGKGEHGKPYPLV--EDECDDSVYKENGFNIYVSNNIALDRSLPDIRHPNCKQKLYLENLPNTSIIIPFHNEGWSSLLRTLHSISNRTPDHLIAEIILVDDYSDREHLKAHLAEYMSR-FPKVRIVRTKKREGLIRTRLLGASVARGEVLTFLDSHCEANINWLPPLLDQIAQNPKTIVCPMIDVIDHNHFGYEAQAGDAMRGAFDWEMYYKRIPIPPELQGPDPSDPYQSPVMAGGLFAVNRQWFWELGGYDTGLEIWGGEQFEISFKVWMCGGSMYDVPCSRVGHIYRKYVPYKVPS-GTSLARNLKRVAETWMDEYTEYIYQRRPE-YRHLSTGDLTAQKELRKHLKCKDFKWYMNTVAWDLPKYYP-PVEPLPAAWGEIRNAAS-GLCVDSKHGSTGTELRLDNCLKEGAERTWAHEQIFTFGWREDIRPGDPLHTRKFCFDAISQNSPITLYDCHGMKGNQHWSYRKDK-SLYHLVSSGCMD--CSPNDKRIFMNKCDPKSETQQWIFQKVNATVLD 592          

Query:  360 ARVGPGEQGIGVYLTANENEKAKQLMETNGYNALASDKISVHRSIKDLRINKCKWLKYDNFLPPASIIIPFHNEHWSTLLRTVHSILHRSPDKLVKEIILVDDNSTKEFLGEKLEQYVSEHFTKVRILRTGKREGLIRARLLGANEANGTVLIFIDSHCEVGINWLPPLLQPIRDHYKTISCPFIDVISYNDFSLRPQDEGGRGAFDW--NFDYKRLPRLSKDNAHPEK--PFYNPIMAGGLFAISKLWFNELGGYDYGLDVWGGEQYELSFKVWMCGGKMVDVPCSRVGHVYRKFNPFAVV-GLGNYLARNHKRIAEVWMDDWKQYIYQKHQKVYSSLDPGDLTEQKKLRKALNCTSFDWFMKQIAYDLLEKYPIQKQPEN-LSQGKIKSEINPHLCFDFNLGNP-GDPFRISNCTDVSNEQNLAFTWEMEIKPQKRDICLDYPRKGEELTMFSCHGMGGNQKWIYNQNSHQIVHVVSKKCIDYRYNPESLEINIQKCSRKLSQKWILENMN 1877
            A   PGE G  V +   E +K K+L + N +N +ASD I+++RS+ D+R++ CK   Y + LP  SI+I FHNE WSTLLRTVHS ++RSP +L+ EI+LVDD S ++FL EKLE YV+     VRILR  +R GLIRARL GA    G V+ F+D+HCE    WL PL+  I++  + + CP IDVIS   F      +   G F+W  NF +  +P+   D    ++  P   P MAGGLF+I + +F E+G YD G+D+WGGE  E+SF++W CGG +  V CS VGHV+RK  P++   G G  + +N++R+AEVWMD++K + Y     V   +D GD++ +K LR++L C  F W+++ +       YP  + P    S G+I++ +  + C D N+G    +     NC  +   Q  ++T + EI+    D+CLD  R    + M  CH M GNQ + Y+     ++HV S +C+D     + +   ++ CS + SQ+WIL NM 
Sbjct:   53 AHEAPGEMGKAVVIPKEEQDKMKELFKINQFNLMASDMIALNRSLPDVRLDGCKTKTYPDDLPNTSIVIVFHNEAWSTLLRTVHSAINRSPRQLLYEILLVDDASERDFLKEKLEDYVATLEVPVRILRMEQRTGLIRARLRGAAATRGQVITFLDAHCECTTGWLEPLMARIKEDRRAVVCPIIDVISDETFEYMAGSDMTYGGFNWKLNFRWYPVPQREMDRRKGDRTLPVRTPTMAGGLFSIDRTYFEEIGTYDSGMDIWGGENLEMSFRIWQCGGSLEIVTCSHVGHVFRKATPYSFPGGTGQVINKNNRRLAEVWMDEFKDFFYIISPGVV-RVDYGDVSSRKALRESLKCKPFSWYLENV-------YPDSQIPRRYYSLGEIRN-VETNQCVD-NMGRKENEKVGFFNCHGMGGNQVFSYTADKEIRTD--DLCLDASRLNGPVVMLKCHHMKGNQMFEYDAERLTLLHVNSNQCLDMPSEEDKMVPTLKDCSGRRSQQWILRNMT 553          

Query:  369 GPGEQGIGVYLTANENEKAKQLMETNGYNALASDKISVHRSIKDLRINKCKWLKYDNFLPPASIIIPFHNEHWSTLLRTVHSILHRSPDKLVKEIILVDDNSTKEFLGEKLEQYVSEHFTKVRILRTGKREGLIRARLLGANEANGTVLIFIDSHCEVGINWLPPLLQPIRDHYKTISCPFIDVISYNDFSLRPQDEGGRGAFDW--NFDYKRLPRLSKDNAHPEK--PFYNPIMAGGLFAISKLWFNELGGYDYGLDVWGGEQYELSFKVWMCGGKMVDVPCSRVGHVYRKFNPFAVV-GLGNYLARNHKRIAEVWMDDWKQYIYQKHQKVYSSLDPGDLTEQKKLRKALNCTSFDWFMKQIAYDLLEKYPIQKQPEN-LSQGKIKSEINPHLCFDFNLGNPGDPFRISNCTDVSNEQNLAFTWEMEIKPQKRDICLDYPRKGEELTMFSCHGMGGNQKWIYNQNSHQIVHVVSKKCIDYRYNPESLEINIQKCSRKLSQKWILENMN 1877
            GPGE G  V +  ++ EK K++ + N +N +AS+ I+++RS+ D+R+  CK   Y + LP  S++I FHNE W+TLLRTVHS++ RSP  L++EI+LVDD S ++FL  +LE YV +    VR++R  +R GLIRARL GA+ + G V+ F+D+HCE    WL PLL  I+   KT+ CP IDVIS + F      +   G F+W  NF +  +P+   D    ++  P   P MAGGLF+I + +F E+G YD G+D+WGGE  E+SF++W CGG +  V CS VGHV+RK  P+    G G  + +N++R+AEVWMD++K + Y     V + +D GD++ +  LR+ L C  F W+++ +       YP  + P +  S G+I++ +  + C D       +   I NC  +   Q  ++T   EI+    D+CLD  +    + M  CH + GNQ W Y+     +VHV S +C+D     +S   +++ CS   SQ+W+L N+ 
Sbjct:   55 GPGEMGKPVVIAKDQQEKMKEMFKINQFNLMASEMIALNRSLPDVRLEGCKTKVYPDDLPRTSVVIVFHNEAWTTLLRTVHSVIDRSPRHLLEEIVLVDDASERDFLKRQLEHYVRKLEVPVRVVRMEQRSGLIRARLKGASISTGQVITFLDAHCECTTGWLEPLLSRIKLDKKTVVCPIIDVISDDTFEYMAGSDMTYGGFNWKLNFRWYPVPQREMDRRKGDRTLPVRTPTMAGGLFSIDRDYFQEIGTYDAGMDIWGGENLEISFRIWQCGGTLEIVTCSHVGHVFRKATPYTFPGGTGQIINKNNRRLAEVWMDEFKNFFYIISPGV-TKVDYGDISTRTSLRQRLQCKPFSWYLENV-------YPDSQIPRHYYSLGEIRN-VETNQCLDNMARKENEKVGIFNCHGMGGNQVFSYTANKEIRTD--DLCLDVSKLNGPVMMLKCHHLKGNQLWEYDPVKLSLVHVNSNQCLDKASEDDSQVPSVRDCSGARSQQWLLRNVT 552          

Query:  369 GPGEQGIGVYLTANENEKAKQLMETNGYNALASDKISVHRSIKDLRINKCKWLKYDNFLPPASIIIPFHNEHWSTLLRTVHSILHRSPDKLVKEIILVDDNSTKEFLGEKLEQYVSEHFTKVRILRTGKREGLIRARLLGANEANGTVLIFIDSHCEVGINWLPPLLQPIRDHYKTISCPFIDVISYNDFSLRPQDEGGRGAFDW--NFDYKRLPRLSKDNAHPEK--PFYNPIMAGGLFAISKLWFNELGGYDYGLDVWGGEQYELSFKVWMCGGKMVDVPCSRVGHVYRKFNPFAVV-GLGNYLARNHKRIAEVWMDDWKQYIYQKHQKVYSSLDPGDLTEQKKLRKALNCTSFDWFMKQIAYDLLEKYPIQKQPEN-LSQGKIKSEINPHLCFDFNLGNPGDPFRISNCTDVSNEQNLAFTWEMEIKPQKRDICLDYPRKGEELTMFSCHGMGGNQKWIYNQNSHQIVHVVSKKCIDYRYNPESLEINIQKCSRKLSQKWILENMN 1877
            GPGE G  V +  ++ EK K++ + N +N +AS+ I+++RS+ D+R+  CK   Y + LP  S++I FHNE W+TLLRTVHS++ RSP  L++EI+LVDD S ++FL  +LE YV +    VR++R  +R GLIRARL GA+ + G V+ F+D+HCE    WL PLL  I+   KT+ CP IDVIS + F      +   G F+W  NF +  +P+   D    ++  P   P MAGGLF+I + +F E+G YD G+D+WGGE  E+SF++W CGG +  V CS VGHV+RK  P+    G G  + +N++R+AEVWMD++K + Y     V + +D GD++ +  LR+ L C  F W+++ +       YP  + P +  S G+I++ +  + C D       +   I NC  +   Q  ++T   EI+    D+CLD  +    + M  CH + GNQ W Y+     +VHV S +C+D     +S   +++ CS   SQ+W+L N+ 
Sbjct:   55 GPGEMGKPVVIAKDQQEKMKEMFKINQFNLMASEMIALNRSLPDVRLEGCKTKVYPDDLPRTSVVIVFHNEAWTTLLRTVHSVIDRSPRHLLEEIVLVDDASERDFLKRQLEHYVRKLEVPVRVVRMEQRSGLIRARLKGASISTGQVITFLDAHCECTTGWLEPLLSRIKLDKKTVVCPIIDVISDDTFEYMAGSDMTYGGFNWKLNFRWYPVPQREMDRRKGDRTLPVRTPTMAGGLFSIDRDYFQEIGTYDAGMDIWGGENLEISFRIWQCGGTLEIVTCSHVGHVFRKATPYTFPGGTGQIINKNNRRLAEVWMDEFKNFFYIISPGV-TKVDYGDISTRTSLRQRLQCKPFSWYLENV-------YPDSQIPRHYYSLGEIRN-VETNQCLDNMARKENEKVGIFNCHGMGGNQVFSYTANKEIRTD--DLCLDVSKLNGPVMMLKCHHLKGNQLWEYDPVKLSLVHVNSNQCLDKASEDDSQVPSVRDCSGARSQQWLLRNVT 552          

Query:  303 SDSQIKIDWANHDTIDEENARVGPGEQGIGVYLTANENEKAKQLMETNGYNALASDKISVHRSIKDLRINKCKWLKYDNFLPPASIIIPFHNEHWSTLLRTVHSILHRSPDKLVKEIILVDDNSTKEFLGEKLEQYVSEHFTKVRILRTGKREGLIRARLLGANEANGTVLIFIDSHCEVGINWLPPLLQPIRDHYKTISCPFIDVISYNDFSLRPQ-DEGGRGAFDWNFDYKRLPRLSK-DNAHPEKPFYNPIMAGGLFAISKLWFNELGGYDYGLDVWGGEQYELSFKVWMCGGKMVDVPCSRVGHVYRKFNPFAVVGLGNYLARNHKRIAEVWMDDWKQYIYQKHQKVYSSLDPGDLTEQKKLRKALNCTSFDWFMKQIAYDLLEKYPIQKQPENLSQGKIKSEINPHLCFDFNLGNPGDPFRISNCT------DVSNEQNLAFTWEMEIKP----QKRDICLDYPRKGEELTMFSCHGMGGNQKWIYNQNSHQIVHVVSKKCIDYRYNPESLEINIQKCSR-KLSQKWILENMNAMI 1886
            +D   + DW ++++I +E  R G GE G    LT  E E+   +   NG+N   S+KI++ RS+ D+R   CK   Y   LP  SIIIPFHNE W++LLRT+HS+++R+PD L++E+ILVDD S +E L EKLE+Y++ ++ KVRI+RT KREGLIR RLLGA+ A G VL F+DSHCEV +NWLPPLL  I  ++KTI CP IDVI +N F    Q  +  RGAFDW   YKR+P   +     P +PF +P+MAGGLFA+ + WF ELGGYD GL++WGGEQYELSFKVWMCGG+M DVPCSRVGH+YRK+ P+  V  G  LARN KR+AE WMD++ +YIYQ+  + Y  L  GD++ QK+LRK L C  F W+M ++A+D+ + YP   +P   S G+I++ +  +LC D   G  G   R+  C         S+EQ   F W  +I+P      R  C D       +T++ CHGM GNQ+W Y ++   + H V+  CID   NP   ++ + +C     +Q+WI E++N  I
Sbjct:   60 TDGLRRKDWHDYESIQKEALRSGKGEHGKPYPLT--EEEQDDTVYRENGFNIFVSNKIALARSLPDIRHPNCKHKLYLERLPNTSIIIPFHNEGWTSLLRTIHSVINRTPDSLIEEMILVDDFSDREHLREKLEEYMA-YYPKVRIVRTKKREGLIRTRLLGASMAKGEVLTFLDSHCEVNVNWLPPLLNQIALNHKTIVCPMIDVIDHNHFGYEAQAGDAMRGAFDWEMYYKRIPIPPELQRTDPSEPFESPVMAGGLFAVDRKWFWELGGYDPGLEIWGGEQYELSFKVWMCGGEMFDVPCSRVGHIYRKYVPYK-VPTGTSLARNLKRVAETWMDEYAEYIYQRRPE-YRHLSTGDISSQKELRKHLKCKDFKWYMSEVAWDVPKFYP-PVEPPPASWGEIRN-VASNLCIDSKHGATGTELRLDTCVKDGSERTWSHEQLFTFGWREDIRPGEPLHTRKFCFDSISHSSPVTLYDCHGMKGNQQWSYRKDK-TLFHPVTNSCID--CNPAEKKLFMNRCDPLSETQQWIFEHVNMTI 590          

Query:  270 KETSDEINEVSSDSQIKIDWANHDTIDEENARVGPGEQGIGVYLTANENEKAKQLMETNGYNALASDKISVHRSIKDLRINKCKWLKYDNFLPPASIIIPFHNEHWSTLLRTVHSILHRSPDKLVKEIILVDDNSTKEFLGEKLEQYVSEHFTKVRILRTGKREGLIRARLLGANEANGTVLIFIDSHCEVGINWLPPLLQPIRDHYKTISCPFIDVISYNDFSLRPQ-DEGGRGAFDWNFDYKRLPRLSK-DNAHPEKPFYNPIMAGGLFAISKLWFNELGGYDYGLDVWGGEQYELSFKVWMCGGKMVDVPCSRVGHVYRKFNPFAVVGLGNYLARNHKRIAEVWMDDWKQYIYQKHQKVYSSLDPGDLTEQKKLRKALNCTSFDWFMKQIAYDLLEKYPIQKQPENLSQGKIKSEINPHLCFDFNLGNPGDPFRISNCTDVSN------EQNLAFTWEMEIKP----QKRDICLDYPRKGEELTMFSCHGMGGNQKWIYNQNSHQIVHVVSKKCIDYRYNPESLEINIQKCS-RKLSQKWILENMNAMI 1886
            K   +++NE   +   K DW N++ I +E+ ++G GEQG    +T  + +   Q    NG+N   SDKIS++RS+ D+R + CK   Y + LP  S+IIPFHNE WS+LLRTVHS+L+RSP +L+ EI+LVDD S K  L  +LE+Y++ +F KV+I+RT KREGLIR R+LGA  A+G VL F+DSHCE  +NWLPPLL P+  +YKT+ CP IDVI  ++F    Q  +  RGAFDW   YKR+P   +     P  PF +P+MAGGLFAI++ WF +LGGYD GL++WGGEQYE+SFKVWMCGG+MVD PCSRVGH+YRK+ P+ V   G  LARN KR+AEVWMD++ +YIYQ+    Y  L  GD+  QK+LR+ L C  F WFM +IA+DL + YP  + P   + G+I++ +   +C        G   R+  C    N       Q     W  +I+P         C D   +   +T+F CHGM GNQ W Y ++   + H  S  C+D   N    +I + KC+    +Q+W  E++N+ I
Sbjct:   55 KPRDEKVNEKVPE---KKDWHNYEQIRKESEQIGNGEQGKPFPMT--DADHVDQAYRENGFNIFVSDKISLNRSLPDIRHSNCKNKFYFSKLPNTSVIIPFHNEGWSSLLRTVHSVLNRSPPELIAEIVLVDDYSDKAHLKSRLEKYMA-NFPKVKIVRTKKREGLIRTRMLGATVASGEVLTFLDSHCEANVNWLPPLLDPLVQNYKTVVCPMIDVIDSDNFGYVTQAGDAMRGAFDWEMFYKRIPIPPELQKGDPSDPFDSPVMAGGLFAINREWFWQLGGYDPGLEIWGGEQYEISFKVWMCGGRMVDSPCSRVGHIYRKYVPYKVPA-GVSLARNLKRVAEVWMDEYAEYIYQRRPD-YRHLSVGDVAAQKELRRKLQCRDFKWFMNEIAWDLPKYYPPVELPP-AAWGEIRN-VRMDMCVGVKHVTSGTEIRLEACNKGRNSDTWGARQVFTLGWREDIRPGIPQHTMKSCFDAVSQTSPVTLFDCHGMKGNQLWKYRRDK-TVYHPTSNSCMD--CNEGEYKIFMNKCNPSSPTQQWTFEHINSTI 593          

Query:  270 KETSDEINEVSSDSQIKIDWANHDTIDEENARVGPGEQGIGVYLTANENEKAKQLMETNGYNALASDKISVHRSIKDLRINKCKWLKYDNFLPPASIIIPFHNEHWSTLLRTVHSILHRSPDKLVKEIILVDDNSTKEFLGEKLEQYVSEHFTKVRILRTGKREGLIRARLLGANEANGTVLIFIDSHCEVGINWLPPLLQPIRDHYKTISCPFIDVISYNDFSLRPQ-DEGGRGAFDWNFDYKRLPRLSK-DNAHPEKPFYNPIMAGGLFAISKLWFNELGGYDYGLDVWGGEQYELSFKVWMCGGKMVDVPCSRVGHVYRKFNPFAVVGLGNYLARNHKRIAEVWMDDWKQYIYQKHQKVYSSLDPGDLTEQKKLRKALNCTSFDWFMKQIAYDLLEKYPIQKQPENLSQGKIKSEINPHLCFDFNLGNPGDPFRISNCTDVSN------EQNLAFTWEMEIKP----QKRDICLDYPRKGEELTMFSCHGMGGNQKWIYNQNSHQIVHVVSKKCIDYRYNPESLEINIQKCS-RKLSQKWILENMNAMI 1886
            K   +++NE   +   K DW N++ I +E+ ++G GEQG    +T  + +   Q    NG+N   SDKIS++RS+ D+R + CK   Y + LP  S+IIPFHNE WS+LLRTVHS+L+RSP +L+ EI+LVDD S K  L  +LE+Y++ +F KV+I+RT KREGLIR R+LGA  A+G VL F+DSHCE  +NWLPPLL P+  +YKT+ CP IDVI  ++F    Q  +  RGAFDW   YKR+P   +     P  PF +P+MAGGLFAI++ WF +LGGYD GL++WGGEQYE+SFKVWMCGG+MVD PCSRVGH+YRK+ P+ V   G  LARN KR+AEVWMD++ +YIYQ+    Y  L  GD+  QK+LR+ L C  F WFM +IA+DL + YP  + P   + G+I++ +   +C        G   R+  C    N       Q     W  +I+P         C D   +   +T+F CHGM GNQ W Y ++   + H  S  C+D   N    +I + KC+    +Q+W  E++N+ I
Sbjct:   55 KPRDEKVNEKVPE---KKDWHNYEQIRKESEQIGNGEQGKPFPMT--DADHVDQAYRENGFNIFVSDKISLNRSLPDIRHSNCKNKFYFSKLPNTSVIIPFHNEGWSSLLRTVHSVLNRSPPELIAEIVLVDDYSDKAHLKSRLEKYMA-NFPKVKIVRTKKREGLIRTRMLGATVASGEVLTFLDSHCEANVNWLPPLLDPLVQNYKTVVCPMIDVIDSDNFGYVTQAGDAMRGAFDWEMFYKRIPIPPELQKGDPSDPFDSPVMAGGLFAINREWFWQLGGYDPGLEIWGGEQYEISFKVWMCGGRMVDSPCSRVGHIYRKYVPYKVPA-GVSLARNLKRVAEVWMDEYAEYIYQRRPD-YRHLSVGDVAAQKELRRKLQCRDFKWFMNEIAWDLPKYYPPVELPP-AAWGEIRN-VRMDMCVGVKHVTSGTEIRLEACNKGRNSDTWGARQVFTLGWREDIRPGIPQHTMKSCFDAVSQTSPVTLFDCHGMKGNQLWKYRRDK-TVYHPTSNSCMD--CNEGEYKIFMNKCNPSSPTQQWTFEHINSTI 593          

Query:  303 SDSQIKIDWANHDTIDEENARVGPGEQGIGVYLTANENEKAKQLMETNGYNALASDKISVHRSIKDLRINKCKWLKYDNFLPPASIIIPFHNEHWSTLLRTVHSILHRSPDKLVKEIILVDDNSTKEFLGEKLEQYVSEHFTKVRILRTGKREGLIRARLLGANEANGTVLIFIDSHCEVGINWLPPLLQPIRDHYKTISCPFIDVISYNDFSLRPQ-DEGGRGAFDWNFDYKRLPRLSK-DNAHPEKPFYNPIMAGGLFAISKLWFNELGGYDYGLDVWGGEQYELSFKVWMCGGKMVDVPCSRVGHVYRKFNPFAVVGLGNYLARNHKRIAEVWMDDWKQYIYQKHQKVYSSLDPGDLTEQKKLRKALNCTSFDWFMKQIAYDLLEKYPIQKQPENLSQGKIKSEINPHLCFDFNLGNPGDPFRISNCTDVSNEQNLAFTWEMEIKP----QKRDICLDYPRKGEELTMFSCHGMGGNQKWIYNQNSHQIVHVVSKKCIDYRYNPESLEINIQKCSR-KLSQKWILENMNAMI 1886
            +D   + DW ++++I +E  R G GE G    LT  E E+   +   NG+N   S+KI++ RS+ D+R   CK   Y   LP  SIIIPFHNE W++LLRT+HS+++R+PD L++E+ILVDD S +E L EKLE+Y++ ++ KVRI+RT KREGLIR RLLGA+ A G VL F+DSHCEV +NWLPPLL  I  ++KTI CP IDVI +N F    Q  +  RGAFDW   YKR+P   +     P +PF +P+MAGGLFA+ + WF ELGGYD GL++WGGEQYELSFKVWMCGG+M DVPCSRVGH+YRK+ P+  V  G  LARN KR+AE WMD++ +YIYQ+  + Y  L  GD++ QK+LRK L C  F W+M ++A+D+ + YP   +P   S G++K                       NC          F W  +I+P      R  C D       +T++ CHGM GNQ+W Y ++   + H V+  CID   NP   ++ + +C     +Q+WI E++N  I
Sbjct:   60 TDGLRRKDWHDYESIQKEALRSGKGEHGKPYPLT--EEEQDDTVYRENGFNIFVSNKIALARSLPDIRHPNCKHKLYLERLPNTSIIIPFHNEGWTSLLRTIHSVINRTPDSLIEEMILVDDFSDREHLREKLEEYMA-YYPKVRIVRTKKREGLIRTRLLGASMAKGEVLTFLDSHCEVNVNWLPPLLNQIALNHKTIVCPMIDVIDHNHFGYEAQAGDAMRGAFDWEMYYKRIPIPPELQRTDPSEPFESPVMAGGLFAVDRKWFWELGGYDPGLEIWGGEQYELSFKVWMCGGEMFDVPCSRVGHIYRKYVPYK-VPTGTSLARNLKRVAETWMDEYAEYIYQRRPE-YRHLSTGDISSQKELRKHLKCKDFKWYMSEVAWDVPKFYP-PVEPPPASWGEVK----------------------INCL-------FTFGWREDIRPGEPLHTRKFCFDSISHSSPVTLYDCHGMKGNQQWSYRKDK-TLFHPVTNSCID--CNPAEKKLFMNRCDPLSETQQWIFEHVNMTI 556          

Query:  303 SDSQIKIDWANHDTIDEENARVGPGEQGIGVYLTANENEKAKQLMETNGYNALASDKISVHRSIKDLRINKCKWLKYDNFLPPASIIIPFHNEHWSTLLRTVHSILHRSPDKLVKEIILVDDNSTKEFLGEKLEQYVSEHFTKVRILRTGKREGLIRARLLGANEANGTVLIFIDSHCEVGINWLPPLLQPIRDHYKTISCPFIDVISYNDFSLRPQ-DEGGRGAFDWNFDYKRLPRLSK-DNAHPEKPFYNPIMAGGLFAISKLWFNELGGYDYGLDVWGGEQYELSFKVWMCGGKMVDVPCSRVGHVYRKFNPFAVVGLGNYLARNHKRIAEVWMDDWKQYIYQKHQKVYSSLDPGDLTEQKKLRKALNCTSFDWFMKQIAYDLLEKYPIQKQPENLSQGKIKSEINPHLCFDFNLGNPGDPFRISNCTDVSNEQNLAFTWEMEIKP----QKRDICLDYPRKGEELTMFSCHGMGGNQKWIYNQ 1745
            +D   + DW ++++I +E  R G GE G    LT  E E+   +   NG+N   S+KI++ RS+ D+R   CK   Y   LP  SIIIPFHNE W++LLRT+HS+++R+PD L++E+ILVDD S +E L EKLE+Y++ ++ KVRI+RT KREGLIR RLLGA+ A G VL F+DSHCEV +NWLPPLL  I  ++KTI CP IDVI +N F    Q  +  RGAFDW   YKR+P   +     P +PF +P+MAGGLFA+ + WF ELGGYD GL++WGGEQYELSFKVWMCGG+M DVPCSRVGH+YRK+ P+  V  G  LARN KR+AE WMD++ +YIYQ+  + Y  L  GD++ QK+LRK L C  F W+M ++A+D+ + YP   +P   S G++K                       NC          F W  +I+P      R  C D       +T++ CHGM GNQ+W Y +
Sbjct:   60 TDGLRRKDWHDYESIQKEALRSGKGEHGKPYPLT--EEEQDDTVYRENGFNIFVSNKIALARSLPDIRHPNCKHKLYLERLPNTSIIIPFHNEGWTSLLRTIHSVINRTPDSLIEEMILVDDFSDREHLREKLEEYMA-YYPKVRIVRTKKREGLIRTRLLGASMAKGEVLTFLDSHCEVNVNWLPPLLNQIALNHKTIVCPMIDVIDHNHFGYEAQAGDAMRGAFDWEMYYKRIPIPPELQRTDPSEPFESPVMAGGLFAVDRKWFWELGGYDPGLEIWGGEQYELSFKVWMCGGEMFDVPCSRVGHIYRKYVPYK-VPTGTSLARNLKRVAETWMDEYAEYIYQRRPE-YRHLSTGDISSQKELRKHLKCKDFKWYMSEVAWDVPKFYP-PVEPPPASWGEVK----------------------INCL-------FTFGWREDIRPGEPLHTRKFCFDSISHSSPVTLYDCHGMKGNQQWSYRK 511          

Query:  324 DWANHDTIDEENARVGPGEQGIGVYLTANENEKAKQLMETNGYNALASDKISVHRSIKDLRINKCKWLKYDNFLPPASIIIPFHNEHWSTLLRTVHSILHRSPDKLVKEIILVDDNSTKEFLGEKLEQYVSEHFTKVRILRTGKREGLIRARLLGANEANGTVLIFIDSHCEVGINWLPPLLQPIRDHYKTISCPFIDVISYNDFSLRPQ-DEGGRGAFDWNFDYKRLPRLSK-DNAHPEKPFYNPIMAGGLFAISKLWFNELGGYDYGLDVWGGEQYELSFKVWMCGGKMVDVPCSRVGHVYRKFNPFAVVGLGNYLARNHKRIAEVWMDDWKQYIYQKHQKVYSSLDPGDLTEQKKLRKALNCTSFDWFMKQIAYDLLEKYPIQKQPENLSQGKIKSEINPHLCFDFNLGNPGDPFRISNCTDVSNE------QNLAFTWEMEIKP----QKRDICLDYPRKGEELTMFSCHGMGGNQKWIYNQNSHQIVHVVSKKCIDYRYNPESLEINIQKCSRKLSQKWILENMNAMI 1886
            DW N + I  +  RVG GEQG    +T  + E+  Q    NG+N   SDKIS++RS+ D+R   C    Y   LP  SIIIPFHNE WS+LLRTVHS+L+RSP +LV EI+LVDD S +E L + LE Y++  F  VRILRT KREGLIR R+LGA+ A G V+ F+DSHCE  +NWLPPLL  I  + KTI CP IDVI ++DF    Q  +  RGAFDW   YKR+P   +   A P  PF +P+MAGGLFA+ + WF ELGGYD GL++WGGEQYE+SFKVWMCGG+M D+PCSRVGH+YRK+ P+ V   G  LARN KR+AEVWMD++ +YIYQ+  + Y  L  GD+  QKKLR +LNC SF WFM +IA+DL + YP   +P   + G+I++ +   LC D  LG  G P R+  C     E      Q   FTW  +I+P      +  C D       +T++ CH M GNQ W Y ++   + H VS  C+D   +   + +N    S  L+Q+W+ E+ N+ +
Sbjct:   73 DWHNKEAIRRDAQRVGYGEQGKPYPMT--DAERVDQAYRENGFNIYVSDKISLNRSLPDIRHPNCNSKLYLETLPNTSIIIPFHNEGWSSLLRTVHSVLNRSPPELVAEIVLVDDFSDREHLKKPLEDYMA-LFPSVRILRTKKREGLIRTRMLGASAATGDVVTFLDSHCEANVNWLPPLLDRIARNRKTIVCPMIDVIDHDDFRYETQAGDAMRGAFDWEMYYKRIPIPPELQKADPSDPFESPVMAGGLFAVDRKWFWELGGYDPGLEIWGGEQYEISFKVWMCGGRMEDIPCSRVGHIYRKYVPYKVPA-GVSLARNLKRVAEVWMDEYAEYIYQRRPE-YRHLSAGDVVAQKKLRVSLNCKSFKWFMTKIAWDLPKFYP-PVEPPAAAWGEIRN-VGTGLCTDTKLGTLGSPLRLETCIRGRGEAAWNSMQVFTFTWREDIRPGDPQHTKKFCFDAVSHTSPVTLYDCHSMKGNQLWKYRKDK-TLYHPVSGSCMDCSESDHRVFMNTCNPS-SLTQQWLFEHTNSTV 596          

Query:  303 SDSQIKIDWANHDTIDEENARVGPGEQGIGVYLTANENEKAKQLMETNGYNALASDKISVHRSIKDLRINKCKWLKYDNFLPPASIIIPFHNEHWSTLLRTVHSILHRSPDKLVKEIILVDDNSTKEFLGEKLEQYVSEHFTKVRILRTGKREGLIRARLLGANEANGTVLIFIDSHCEVGINWLPPLLQPIRDHYKTISCPFIDVISYNDFSLRPQ-DEGGRGAFDWNFDYKRLPRLSK-DNAHPEKPFYNPIMAGGLFAISKLWFNELGGYDYGLDVWGGEQYELSFKVWMCGGKMVDVPCSRVGHVYRKFNPFAVVGLGNYLARNHKRIAEVWMDDWKQYIYQKHQKVYSSLDPGDLTEQKKLRKALNCTSFDWFMKQIAYDLLEKYPIQKQPENLSQGKIKSEINPHLCFDFNLGNPGDPFRISNCT------DVSNEQNLAFTWEMEIKP----QKRDICLDYPRKGEELTMFSCHGMGGNQKWIYNQNSHQIVHVVSKKCIDYRYNPESLEINIQKCS-RKLSQKWILENMNAMI 1886
            +D   + DW ++++I  +  R G GE G    LT  E ++       NG+N   S+ I++ RS+ D+R   CK   Y   LP  SIIIPFHNE W++LLRT+HSI++R+P+ L+ EIILVDD S +E L +KLE Y++  F+KVRI+RT KREGLIR RLLGA+ A G VL F+DSHCEV +NWLPPLL  I  ++KTI CP IDVI +N F    Q  +  RGAFDW   YKR+P   +   A P  PF +P+MAGGLFA+ + WF ELGGYD GL++WGGEQYE+SFKVWMCGG+M DVPCSRVGH+YRK+ P+ V   G  LARN KR+AE WMD++ +YIYQ+  + Y  L  GD++ QK+LRK L C  F WFM  +A+D+ + YP   +P   + G+I+S +  +LC D   G  G   R+  C         S+EQ   F W  +I+P      R  CLD       +T++ CHGM GNQ W Y ++   + H VS  C+D   NP   +I + +C     +Q+WI E++N  +
Sbjct:   61 TDGLRRKDWHDYESIQRDALRSGKGEHGKPYPLT--EEDRDDSAYRENGFNIFVSNNIALERSLPDIRHANCKHKMYLERLPNTSIIIPFHNEGWTSLLRTIHSIINRTPESLIAEIILVDDFSDREHLKDKLEDYMAR-FSKVRIVRTKKREGLIRTRLLGASVARGEVLTFLDSHCEVNVNWLPPLLNQIALNHKTIVCPMIDVIDHNHFGYEAQAGDAMRGAFDWEMYYKRIPIPPELQRADPSDPFESPVMAGGLFAVDRKWFWELGGYDPGLEIWGGEQYEISFKVWMCGGEMFDVPCSRVGHIYRKYVPYKVPS-GTSLARNLKRVAETWMDEFAEYIYQRRPE-YRHLSTGDISAQKELRKRLKCKDFKWFMAAVAWDVPKYYP-PVEPLPAAWGEIRS-VAANLCVDSKHGATGTELRLDVCVKDGSERTWSHEQLFTFGWREDIRPGEPLHTRKFCLDAISHSSPVTLYDCHGMKGNQLWGYRED-RTLFHPVSNSCMD--CNPSEKKIFMARCDPLSETQQWIFEHINMTV 591          

Query:  369 GPGEQGIGVYLTANENEKAKQLMETNGYNALASDKISVHRSIKDLRINKCKWLKYDNFLPPASIIIPFHNEHWSTLLRTVHSILHRSPDKLVKEIILVDDNSTKEFLGEKLEQYVSEHFTKVRILRTGKREGLIRARLLGANEANGTVLIFIDSHCEVGINWLPPLLQPIRDHYKTISCPFIDVISYNDFSLRPQDEGGRGAFDW--NFDYKRLPRLSKDNAHPEK--PFYNPIMAGGLFAISKLWFNELGGYDYGLDVWGGEQYELSFKVWMCGGKMVDVPCSRVGHVYRKFNPFAVV-GLGNYLARNHKRIAEVWMDDWKQYIYQKHQKVYSSLDPGDLTEQKKLRKALNCTSFDWFMKQIAYDLLEKYPIQKQPEN-LSQGKIKSEINPHLCFDFNLGNP-GDPFRISNCTDVSNEQNLAFTWEMEIKPQKRDICLDYPRKGEELTMFSCHGMGGNQKWIYNQNSHQIVHVVSKKCIDYRYNPESLEINIQKCSRKLSQKWILENMN 1877
            GPGE G  V +  ++ EK K+L + N +N +ASD I+++RS+ D+R+  CK   Y + LP  S++I FHNE WSTLLRTV+S+++RSP  L+ E+ILVDD S ++FL   LE YV      V+I+R  +R GLIRARL GA  + G V+ F+D+HCE  + WL PLL  I++  KT+ CP IDVIS + F      +   G F+W  NF +  +P+   D    ++  P   P MAGGLF+I + +F E+G YD G+D+WGGE  E+SF++W CGG +  V CS VGHV+RK  P+    G G+ + +N++R+AEVWMD++K + Y     V   +D GD++ +K LR+ L C  F W+++ I       YP  + P    S G+I++ +  + C D N+G    +   I NC  +   Q  ++T + EI+    D+CLD  R    + M  CH M GNQ W Y+     + H  S +C+D     + +   +Q CS   SQ+W+L NM 
Sbjct:   56 GPGEMGKAVLIPKDDQEKMKELFKINQFNLMASDLIALNRSLPDVRLEGCKTKVYPDELPNTSVVIVFHNEAWSTLLRTVYSVINRSPHYLLSEVILVDDASERDFLKLTLENYVKTLEVPVKIIRMEERSGLIRARLRGAAASKGQVITFLDAHCECTLGWLEPLLARIKEDRKTVVCPIIDVISDDTFEYMAGSDMTYGGFNWKLNFRWYPVPQREMDRRKGDRTLPVRTPTMAGGLFSIDRNYFEEIGTYDAGMDIWGGENLEMSFRIWQCGGSLEIVTCSHVGHVFRKATPYTFPGGTGHVINKNNRRLAEVWMDEFKDFFYIISPGVV-KVDYGDVSVRKTLRENLKCKPFSWYLENI-------YPDSQIPRRYYSLGEIRN-VETNQCLD-NMGRKENEKVGIFNCHGMGGNQVFSYTADKEIRTD--DLCLDVSRLSGPVIMLKCHHMRGNQLWEYDAERLTLRHANSNQCLDEPSEEDKMVPTMQDCSGSRSQQWLLRNMT 553          

Query:  369 GPGEQGIGVYLTANENEKAKQLMETNGYNALASDKISVHRSIKDLRINKCKWLKYDNFLPPASIIIPFHNEHWSTLLRTVHSILHRSPDKLVKEIILVDDNSTKEFLGEKLEQYVSEHFTKVRILRTGKREGLIRARLLGANEANGTVLIFIDSHCEVGINWLPPLLQPIRDHYKTISCPFIDVISYNDFSLRPQDEGGRGAFDW--NFDYKRLPRLSKDNAHPEK--PFYNPIMAGGLFAISKLWFNELGGYDYGLDVWGGEQYELSFKVWMCGGKMVDVPCSRVGHVYRKFNPFAVV-GLGNYLARNHKRIAEVWMDDWKQYIYQKHQKVYSSLDPGDLTEQKKLRKALNCTSFDWFMKQIAYDLLEKYPIQKQPEN-LSQGKIKSEINPHLCFDFNLGNP-GDPFRISNCTDVSNEQNLAFTWEMEIKPQKRDICLDYPRKGEELTMFSCHGMGGNQKWIYNQNSHQIVHVVSKKCIDYRYNPESLEINIQKCSRKLSQKWILENMN 1877
            GPGE G  V +  ++ EK K+L + N +N +ASD I+++RS+ D+R+  CK   Y + LP  S++I FHNE WSTLLRTV+S+++RSP  L+ E+ILVDD S ++FL   LE YV      V+I+R  +R GLIRARL GA  + G V+ F+D+HCE  + WL PLL  I++  KT+ CP IDVIS + F      +   G F+W  NF +  +P+   D    ++  P   P MAGGLF+I + +F E+G YD G+D+WGGE  E+SF++W CGG +  V CS VGHV+RK  P+    G G+ + +N++R+AEVWMD++K + Y     V   +D GD++ +K LR+ L C  F W+++ I       YP  + P    S G+I++ +  + C D N+G    +   I NC  +   Q  ++T + EI+    D+CLD  R    + M  CH M GNQ W Y+     + H  S +C+D     + +   +Q CS   SQ+W+L NM 
Sbjct:   56 GPGEMGKAVLIPKDDQEKMKELFKINQFNLMASDLIALNRSLPDVRLEGCKTKVYPDELPNTSVVIVFHNEAWSTLLRTVYSVINRSPHYLLSEVILVDDASERDFLKLTLENYVKTLEVPVKIIRMEERSGLIRARLRGAAASKGQVITFLDAHCECTLGWLEPLLARIKEDRKTVVCPIIDVISDDTFEYMAGSDMTYGGFNWKLNFRWYPVPQREMDRRKGDRTLPVRTPTMAGGLFSIDRNYFEEIGTYDAGMDIWGGENLEMSFRIWQCGGSLEIVTCSHVGHVFRKATPYTFPGGTGHVINKNNRRLAEVWMDEFKDFFYIISPGVV-KVDYGDVSVRKTLRENLKCKPFSWYLENI-------YPDSQIPRRYYSLGEIRN-VETNQCLD-NMGRKENEKVGIFNCHGMGGNQVFSYTADKEIRTD--DLCLDVSRLSGPVIMLKCHHMRGNQLWEYDAERLTLRHANSNQCLDEPSEEDKMVPTMQDCSGSRSQQWLLRNMT 553          

Query:  369 GPGEQGIGVYLTANENEKAKQLMETNGYNALASDKISVHRSIKDLRINKCKWLKYDNFLPPASIIIPFHNEHWSTLLRTVHSILHRSPDKLVKEIILVDDNSTKEFLGEKLEQYVSEHFTKVRILRTGKREGLIRARLLGANEANGTVLIFIDSHCEVGINWLPPLLQPIRDHYKTISCPFIDVISYNDFSLRPQDEGGRGAFDW--NFDYKRLPRLSKDNAHPEK--PFYNPIMAGGLFAISKLWFNELGGYDYGLDVWGGEQYELSFKVWMCGGKMVDVPCSRVGHVYRKFNPFAVV-GLGNYLARNHKRIAEVWMDDWKQYIYQKHQKVYSSLDPGDLTEQKKLRKALNCTSFDWFMKQIAYDLLEKYPIQKQPEN-LSQGKIKSEINPHLCFDFNLGNP-GDPFRISNCTDVSNEQNLAFTWEMEIKPQKRDICLDYPRKGEELTMFSCHGMGGNQKWIYNQNSHQIVHVVSKKCIDYRYNPESLEINIQKCSRKLSQKWILENMN 1877
            GPGE G  V +  ++ EK K+L + N +N +ASD I+++RS+ D+R+  CK   Y + LP  S++I FHNE WSTLLRTV+S+++RSP  L+ E+ILVDD S ++FL   LE YV      V+I+R  +R GLIRARL GA  + G V+ F+D+HCE  + WL PLL  I++  KT+ CP IDVIS + F      +   G F+W  NF +  +P+   D    ++  P   P MAGGLF+I + +F E+G YD G+D+WGGE  E+SF++W CGG +  V CS VGHV+RK  P+    G G+ + +N++R+AEVWMD++K + Y     V   +D GD++ +K LR+ L C  F W+++ I       YP  + P    S G+I++ +  + C D N+G    +   I NC  +   Q  ++T + EI+    D+CLD  R    + M  CH M GNQ W Y+     + H  S +C+D     + +   +Q CS   SQ+W+L NM 
Sbjct:   56 GPGEMGKAVLIPKDDQEKMKELFKINQFNLMASDLIALNRSLPDVRLEGCKTKVYPDELPNTSVVIVFHNEAWSTLLRTVYSVINRSPHYLLSEVILVDDASERDFLKLTLENYVKTLEVPVKIIRMEERSGLIRARLRGAAASKGQVITFLDAHCECTLGWLEPLLARIKEDRKTVVCPIIDVISDDTFEYMAGSDMTYGGFNWKLNFRWYPVPQREMDRRKGDRTLPVRTPTMAGGLFSIDRNYFEEIGTYDAGMDIWGGENLEMSFRIWQCGGSLEIVTCSHVGHVFRKATPYTFPGGTGHVINKNNRRLAEVWMDEFKDFFYIISPGVV-KVDYGDVSVRKTLRENLKCKPFSWYLENI-------YPDSQIPRRYYSLGEIRN-VETNQCLD-NMGRKENEKVGIFNCHGMGGNQVFSYTADKEIRTD--DLCLDVSRLSGPVIMLKCHHMRGNQLWEYDAERLTLRHANSNQCLDEPSEEDKMVPTMQDCSGSRSQQWLLRNMT 553          

Query:  318 KIDWANHDTIDEENARVGPGEQGIGVYLTAN-ENEK-AKQLMETNGYNALASDKISVHRSIKDLRINKCKWLKYDNFLPPASIIIPFHNEHWSTLLRTVHSILHRSPDKLVKEIILVDDNSTKEFLGEKLEQYVSEHFTK--VRILRTGKREGLIRARLLGANEANGTVLIFIDSHCEVGINWLPPLLQPIRDHYKTISCPFIDVISYNDFSLRPQDEGGRGAFDWNFDYKRLPRLSKDNAHPEKPFYNPIMAGGLFAISKLWFNELGGYDYGLDVWGGEQYELSFKVWMCGGKMVDVPCSRVGHVYR-KFNPFAVVGLGNYLARNHKRIAEVWMDDWKQYIYQKHQKVYSSLDPGDLTEQKKLRKALNCTSFDWFMKQIAYDLLEKYPIQKQPENLSQGKIKSEINPHLCFDFNLGNPGDPFRISNCT----DVSNEQNLAFTWEMEIKPQKRDICLDYPRKGEE--LTMFSCHGMGGNQKWIYNQNSHQIVHVVSKKCIDYRYNPESLEINIQKC--SRKLSQKWILENMN 1877
            KI W +    +++ AR GPGE G  V L  + E EK A  L + NGYNA  SD IS++RSIKD+R  +CK + Y   LP  S+I PFH EH STLLR+V+S+++RSP +L+KEIILVDD S K  L + LE ++ ++     V+ILRT KREGLIR R LGA EA G +LIF+D+H E   NWLPPLL PI D Y+T+ CPF+DVI    + +RPQDEG RG+FDW F+YKRLP   KD  +P KPF +P+MAGG FAIS  WF ELGGYD GLD+WGGEQYELSFKVW C GKMVD PCSRV H+YR K+ PF   G+G++++RN+KR+AEVWMD++K+ +Y KH+    + D GDL   K +R+ L C SFDWFMK+IA+D  + YP   +P+  ++G+I+  +  +LC D         F +  C     D   EQ+L  T   +I+P+ R IC D     ++  + +F CH M GNQ + Y     QI H VS +C+    N +   ++++KC  S KL Q+W  + ++
Sbjct:   86 KIKWEDEVAYEKDKAREGPGEWGKPVKLPDDKETEKEALSLYKANGYNAYISDMISLNRSIKDIRHKECKKMTYSAKLPTVSVIFPFHEEHNSTLLRSVYSVINRSPPELLKEIILVDDFSEKPALRQPLEDFLKKNKIDHIVKILRTKKREGLIRGRQLGAQEATGEILIFLDAHSECNYNWLPPLLDPIADDYRTVVCPFVDVIDCETYEIRPQDEGARGSFDWAFNYKRLPLTKKDRENPTKPFDSPVMAGGYFAISAKWFWELGGYDEGLDIWGGEQYELSFKVWQCHGKMVDAPCSRVAHIYRCKYAPFKNAGMGDFVSRNYKRVAEVWMDEYKETLY-KHRPGIGNADAGDLKLMKGIREKLQCKSFDWFMKEIAFDQDKYYPAI-EPKASAEGEIR-HVASNLCIDTQFKEQNQRFGLRKCASEDKDGGGEQDLRLTRWHDIRPKGRKICFDVSTSVDKAPIILFDCHSMKGNQLFKYRMPQKQIYHPVSGQCLTADENGKGF-LHMKKCDSSSKL-QQWAWQTID 613          

Query:  318 KIDWANHDTIDEENARVGPGEQGIGVYLTANEN--EKAKQLMETNGYNALASDKISVHRSIKDLRINKCKWLKYDNFLPPASIIIPFHNEHWSTLLRTVHSILHRSPDKLVKEIILVDDNSTKEFLGEKLEQYVSEHFTK--VRILRTGKREGLIRARLLGANEANGTVLIFIDSHCEVGINWLPPLLQPIRDHYKTISCPFIDVISYNDFSLRPQDEGGRGAFDWNFDYKRLPRLSKDNAHPEKPFYNPIMAGGLFAISKLWFNELGGYDYGLDVWGGEQYELSFKVWMCGGKMVDVPCSRVGHVYR-KFNPFAVVGLGNYLARNHKRIAEVWMDDWKQYIYQKHQKVYSSLDPGDLTEQKKLRKALNCTSFDWFMKQIAYDLLEKYPIQKQPENLSQGKIKSEINPHLCFDFNLGNPGDPFRISNCT----DVSNEQNLAFTWEMEIKPQKRDICLDYPRKGEE--LTMFSCHGMGGNQKWIYNQNSHQIVHVVSKKCIDYRYNPESLEINIQKC-SRKLSQKWILENMN 1877
            KI W +    ++E  R GPGE G  V L  ++   ++A  L + NGYNA  SD IS++RSIKD+R  +CK + Y   LP  S+I PFH EH STLLR+V+S+++RSP +L+KEIILVDD S K  L + LE ++ ++     V++LRT KREGLIR R LGA +A G +LIF+D+H E   NWLPPLL PI + Y+T+ CPF+DVI    + +RPQDEG RG+FDW F+YKRLP   KD   P KPF +P+MAGG FAIS  WF ELGGYD GLD+WGGEQYELSFKVW C G+MVD PCSRV H+YR K+ PF   G+G++++RN+KR+AEVWMDD+K+ +Y KH+    + D GDL   K +R+ L C SFDWFMK+IA+D  + YP   +P+  ++G+I++ +  + C D         F +  CT    D   EQ+L  T   +I+P+ R IC D     ++  + +F CH M GNQ + Y     QI H +S +C+    N +   ++++KC S    QKW  + ++
Sbjct:  141 KIKWEDEAAYEKEKRREGPGEWGKPVKLPEDKEVEKEALSLYKANGYNAYISDMISLNRSIKDIRHKECKNMMYSAKLPTVSVIFPFHEEHNSTLLRSVYSVINRSPPELLKEIILVDDFSEKPALRQPLEDFLKKNKIDHIVKVLRTKKREGLIRGRQLGAQDATGEILIFLDAHSEANYNWLPPLLDPIAEDYRTVVCPFVDVIDCETYEVRPQDEGARGSFDWAFNYKRLPLTKKDRESPTKPFNSPVMAGGYFAISAKWFWELGGYDEGLDIWGGEQYELSFKVWQCHGRMVDAPCSRVAHIYRCKYAPFKNAGMGDFVSRNYKRVAEVWMDDYKETLY-KHRPGVGNADAGDLKLMKGIREKLQCKSFDWFMKEIAFDQDKYYPAV-EPKASAEGEIRN-VGTNFCIDTQFKEQNQRFGLRKCTSDDKDGGGEQDLRLTRWHDIRPKGRKICFDCSTSVDKAPVILFDCHSMKGNQLFKYRVAQKQIYHPISGQCLTADENGKGF-LHMKKCDSSSDLQKWAWQTVD 668          

Query:  324 DWANHDTIDEENARVGPGEQGIGVYLTANENEKAKQLMETNGYNALASDKISVHRSIKDLRINKCKWLKYDNFLPPASIIIPFHNEHWSTLLRTVHSILHRSPDKLVKEIILVDDNSTKEFLGEKLEQYVSEHFTKVRILRTGKREGLIRARLLGANEANGTVLIFIDSHCEVGINWLPPLLQPIRDHYKTISCPFIDVISYNDFSLRPQ-DEGGRGAFDWNFDYKRLPRLSK-DNAHPEKPFYNPIMAGGLFAISKLWFNELGGYDYGLDVWGGEQYELSFKVWMCGGKMVDVPCSRVGHVYRKFNPFAVVGLGNYLARNHKRIAEVWMDDWKQYIYQKHQKVYSSLDPGDLTEQKKLRKALNCTSFDWFMKQIAYDLLEKYPIQKQPENLSQGKIKSEINPHLCFDFNLGNPGDPFRISNCTDVSNE------QNLAFTWEMEIKP----QKRDICLDYPRKGEELTMFSCHGMGGNQKWIYNQNSHQIVHVVSKKCIDYRYNPESLEINIQKCSRKLSQKWILENMNAMI 1886
            DW N + I  +  RVG GEQG    +T  + E+  Q    NG+N   SDKIS++RS+ D+R   C    Y   LP  SIIIPFHNE WS+LLRTVHS+L+RSP +LV EI+LVDD S +E L + LE Y++  F  VRILRT KREGLIR R+LGA+ A G V+ F+DSHCE  +NWLPPLL  I  + KTI CP IDVI ++DF    Q  +  RGAFDW   YKR+P   +   A P  PF +P+MAGGLFA+ + WF ELGGYD GL++WGGEQYE+SFKVWMCGG+M D+PCSRVGH+YRK+ P+ V   G  LARN KR+AEVWMD++ +YIYQ+  + Y  L  GD+  QKKLR +LNC SF WFM +IA+DL + YP   +P   + G+I++ +   LC D  LG  G P R+  C     E      Q   FTW  +I+P      +  C D       +T++ CH M GNQ W Y ++   + H VS  C+D   +   + +N    S  L+Q+W+ E+ N+ +
Sbjct:   73 DWHNKEAIRRDAQRVGYGEQGKPYPMT--DAERVDQAYRENGFNIYVSDKISLNRSLPDIRHPNCNSKLYLETLPNTSIIIPFHNEGWSSLLRTVHSVLNRSPPELVAEIVLVDDFSDREHLKKPLEDYMA-LFPSVRILRTKKREGLIRTRMLGASAATGDVVTFLDSHCEANVNWLPPLLDRIARNRKTIVCPMIDVIDHDDFRYETQAGDAMRGAFDWEMYYKRIPIPPELQKADPSDPFESPVMAGGLFAVDRKWFWELGGYDPGLEIWGGEQYEISFKVWMCGGRMEDIPCSRVGHIYRKYVPYKVPA-GVSLARNLKRVAEVWMDEYAEYIYQRRPE-YRHLSAGDVVAQKKLRVSLNCKSFKWFMTKIAWDLPKFYP-PVEPPAAAWGEIRN-VGTGLCTDTKLGTLGSPLRLETCIRGRGEAAWNSMQVFTFTWREDIRPGDPQHTKKFCFDAVSHTSPVTLYDCHSMKGNQLWKYRKDK-TLYHPVSGSCMDCSESDHRVFMNTCNPS-SLTQQWLFEHTNSTV 596          

Query:  324 DWANHDTIDEENARVGPGEQGIGVYLTANENEKAKQLMETNGYNALASDKISVHRSIKDLRINKCKWLKYDNFLPPASIIIPFHNEHWSTLLRTVHSILHRSPDKLVKEIILVDDNSTKEFLGEKLEQYVSEHFTKVRILRTGKREGLIRARLLGANEANGTVLIFIDSHCEVGINWLPPLLQPIRDHYKTISCPFIDVISYNDFSLRPQ-DEGGRGAFDWNFDYKRLPRLSK-DNAHPEKPFYNPIMAGGLFAISKLWFNELGGYDYGLDVWGGEQYELSFKVWMCGGKMVDVPCSRVGHVYRKFNPFAVVGLGNYLARNHKRIAEVWMDDWKQYIYQKHQKVYSSLDPGDLTEQKKLRKALNCTSFDWFMKQIAYDLLEKYPIQKQPENLSQGKIKSEINPHLCFDFNLGNPGDPFRISNCTDVSNE------QNLAFTWEMEIKP----QKRDICLDYPRKGEELTMFSCHGMGGNQKWIYNQNSHQIVHVVSKKCIDYRYNPESLEINIQKCSRKLSQKWILENMNAMI 1886
            DW N + I  +  RVG GEQG    +T  + E+  Q    NG+N   SDKIS++RS+ D+R   C    Y   LP  SIIIPFHNE WS+LLRTVHS+L+RSP +LV EI+LVDD S +E L + LE Y++  F  VRILRT KREGLIR R+LGA+ A G V+ F+DSHCE  +NWLPPLL  I  + KTI CP IDVI ++DF    Q  +  RGAFDW   YKR+P   +   A P  PF +P+MAGGLFA+ + WF ELGGYD GL++WGGEQYE+SFKVWMCGG+M D+PCSRVGH+YRK+ P+ V   G  LARN KR+AEVWMD++ +YIYQ+  + Y  L  GD+  QKKLR +LNC SF WFM +IA+DL + YP   +P   + G+I++ +   LC D   G  G P R+  C     E      Q   FTW  +I+P      +  C D       +T++ CH M GNQ W Y ++   + H VS  C+D   +   + +N    S  L+Q+W+ E+ N+ +
Sbjct:   73 DWHNKEAIRRDAQRVGNGEQGKPYPMT--DAERVDQAYRENGFNIYVSDKISLNRSLPDIRHPNCNSKLYLETLPNTSIIIPFHNEGWSSLLRTVHSVLNRSPPELVAEIVLVDDFSDREHLKKPLEDYMA-LFPSVRILRTKKREGLIRTRMLGASAATGDVITFLDSHCEANVNWLPPLLDRIARNRKTIVCPMIDVIDHDDFRYETQAGDAMRGAFDWEMYYKRIPIPPELQKADPSDPFESPVMAGGLFAVDRKWFWELGGYDPGLEIWGGEQYEISFKVWMCGGRMEDIPCSRVGHIYRKYVPYKVPA-GVSLARNLKRVAEVWMDEYAEYIYQRRPE-YRHLSAGDVVAQKKLRGSLNCKSFKWFMTKIAWDLPKFYP-PVEPPAAAWGEIRN-VGTGLCTDTKHGTLGSPLRLETCIRGRGEAAWNSMQVFTFTWREDIRPGDPQHTKKFCFDAVSHTSPVTLYDCHSMKGNQLWKYRKDK-TLYHPVSGSCMDCSESDHRIFMNTCNPS-SLTQQWLFEHTNSTV 596          

Query:  306 DSQIKIDWANHDTIDEENARVGPGEQGIGVYLTANENEKAKQLMETNGYNALASDKISVHRSIKDLRINKCKWLKYDNFLPPASIIIPFHNEHWSTLLRTVHSILHRSPDKLVKEIILVDDNSTKEFLGEKLEQYVSEHFTKVRILRTGKREGLIRARLLGANEANGTVLIFIDSHCEVGINWLPPLLQPIRDHYKTISCPFIDVISYNDFSLRPQ-DEGGRGAFDWNFDYKRLPRLSK-DNAHPEKPFYNPIMAGGLFAISKLWFNELGGYDYGLDVWGGEQYELSFKVWMCGGKMVDVPCSRVGHVYRKFNPFAVVGLGNYLARNHKRIAEVWMDDWKQYIYQKHQKVYSSLDPGDLTEQKKLRKALNCTSFDWFMKQIAYDLLEKYPIQKQPENLSQGKIKSEINPHLCFDFNLGNPGDPFRISNCTDVSNE------QNLAFTWEMEIKP----QKRDICLDYPRKGEELTMFSCHGMGGNQKWIYNQNSHQIVHVVSKKCIDYRYNPESLEINIQKCSRKLSQKWILENMNAMI 1886
            D Q   DW + + I  +  RVG GEQG    +T  + E+  Q    NG+N   SDKIS++RS+ D+R   C   +Y   LP  SIIIPFHNE WS+LLRTVHS+L+RSP +LV EI+LVDD S +E L + LE Y++  F  VRILRT KREGLIR R+LGA+ A G V+ F+DSHCE  +NWLPPLL  I  + KTI CP IDVI ++DF    Q  +  RGAFDW   YKR+P   +   A P  PF +P+MAGGLFA+ + WF ELGGYD GL++WGGEQYE+SFKVWMCGG+M D+PCSRVGH+YRK+ P+ V   G  LARN KR+AEVWMD++ +YIYQ+  + Y  L  GD+  QKKLR +LNC SF WFM +IA+DL + YP   +P   + G+I++ +   LC D   G  G P R+  C     E      Q   FTW  +I+P      +  C D       +T++ CH M GNQ W Y ++   + H VS  C+D   +   + +N    S  L+Q+W+ E+ N+ +
Sbjct:   67 DGQKLKDWHDKEAIRRDAQRVGNGEQGRPYPMT--DAERVDQAYRENGFNIYVSDKISLNRSLPDIRHPNCNSKRYLETLPNTSIIIPFHNEGWSSLLRTVHSVLNRSPPELVAEIVLVDDFSDREHLKKPLEDYMA-LFPSVRILRTKKREGLIRTRMLGASVATGDVITFLDSHCEANVNWLPPLLDRIARNRKTIVCPMIDVIDHDDFRYETQAGDAMRGAFDWEMYYKRIPIPPELQKADPSDPFESPVMAGGLFAVDRKWFWELGGYDPGLEIWGGEQYEISFKVWMCGGRMEDIPCSRVGHIYRKYVPYKVPA-GVSLARNLKRVAEVWMDEYAEYIYQRRPE-YRHLSAGDVAVQKKLRSSLNCKSFKWFMTKIAWDLPKFYP-PVEPPAAAWGEIRN-VGTGLCADTKHGALGSPLRLEGCVRGRGEAAWNNMQVFTFTWREDIRPGDPQHTKKFCFDAISHTSPVTLYDCHSMKGNQLWKYRKDK-TLYHPVSGSCMDCSESDHRIFMNTCNPS-SLTQQWLFEHTNSTV 596          

Query:  270 KETSDEINEVSSDSQIKIDWANHDTIDEENARVGPGEQGIGVYLTANENEKAKQLMETNGYNALASDKISVHRSIKDLRINKCKWLKYDNFLPPASIIIPFHNEHWSTLLRTVHSILHRSPDKLVKEIILVDDNSTKEFLGEKLEQYVSEHFTKVRILRTGKREGLIRARLLGANEANGTVLIFIDSHCEVGINWLPPLLQPIRDHYKTISCPFIDVISYNDFSLRPQDEGGRGAFDWNFDYKRLPRLSKDNAHPEKPFYNPIMAGGLFAISKLWFNELGGYDYGLDVWGGEQYELSFKVWMCGGKMVDVPCSRVGHVYRKFNPFAVVGLGNYLARNHKRIAEVWMDDWKQYIYQKHQKVYSSLDPGDLTEQKKLRKALNCTSFDWFMKQIAYDLLEKYPIQKQPENLSQGKIKSEINPHLCFDFNLGNPGDPFRISNCTDV---SNEQNLAFTWEMEIKPQKRDICLDYPRKGEE--LTMFSCHGMGGNQKWIYNQNSHQIVHVVSKKCIDYRYNPESLEINIQKCSRKLSQKWILE 1868
            +E  D+I   +   + KIDW +++ I  E  R GPGEQG    +TA+E +  ++L  TNG+NALASDKIS+ RS+KD+R + CK  KY  +LP  S IIPFHNEH STLLR+VHSIL+R+P  LVKE+IL DD STK+   + L+ YV+++F  VR++R  +REGLIR RLLGA  A G VL+F+DSH E  IN+LPPLL+PI D+Y+T+ CPFIDVI Y +F+ R QDEG RGAFDW   YKRLP   +D A P KPF NPIMAGGLFAIS+ WF ELGGYD GLD+WGGEQYELSFKVW CGG MVD PCSR+GH+YR+F PF   G+G+++ RN+KR+AEVWMD++  YIY++    Y ++D GDLTEQK +R+ LNC  F WFMK++AYDL++ YP   +P+ L+ G+I+   N  +C D       D   +  C+       EQ   F+W  +++P++R+IC D  R   +  + +FSCHGMGGNQ++ YN ++HQI H +S +C+D   N E+ EI +  C    SQ W+ E
Sbjct:   63 REIFDDILVKTRPKEEKIDWHDYNAIAAEKIREGPGEQGTAYLMTADEEKAKQELYRTNGFNALASDKISLERSLKDIRHSDCKRQKYFKYLPTTSFIIPFHNEHLSTLLRSVHSILNRAPPSLVKEVILADDCSTKDECKQPLDDYVAQNFKNVRVVRAAQREGLIRTRLLGARNATGEVLVFLDSHIECNINFLPPLLEPIADNYRTVVCPFIDVIDYENFAYRAQDEGARGAFDWEMYYKRLPLPPEDLAEPSKPFKNPIMAGGLFAISRDWFWELGGYDPGLDIWGGEQYELSFKVWQCGGTMVDAPCSRIGHIYRRFAPFPNPGVGDFVGRNYKRVAEVWMDEFADYIYRRRPH-YRNIDAGDLTEQKAIREKLNCKPFSWFMKEVAYDLVKFYP-PVEPKPLATGEIRRN-NTDMCVDTGFKGANDRIDLHKCSKSLGGGAEQQFEFSWHKDLRPRRRNICFDVSRSSPKSPVVLFSCHGMGGNQRFKYNLDTHQIYHPISGQCLD--SNLETEEIYMNPCKPIPSQVWLFE 595          

Query:  249 QNILSDWKETSDEINEVSSDSQIKIDWANHDTIDEENARVGPGEQGIGVYLTANENEKAKQLMETNGYNALASDKISVHRSIKDLRINKCKWLKYDNFLPPASIIIPFHNEHWSTLLRTVHSILHRSPDKLVKEIILVDDNSTKEFLGEKLEQYVSEHFTKVRILRTGKREGLIRARLLGANEANGTVLIFIDSHCEVGINWLPPLLQPIRDHYKTISCPFIDVISYNDFSLRPQDEGGRGAFDWNFDYKRLPRLSKDNAHPEKPFYNPIMAGGLFAISKLWFNELGGYDYGLDVWGGEQYELSFKVWMCGGKMVDVPCSRVGHVYRKFNPFAVVGLGNYLARNHKRIAEVWMDDWKQYIYQKHQKVYSSLDPGDLTEQKKLRKALNCTSFDWFMKQIAYDLLEKYPIQKQPENLSQGKIKSEINPHLCFDFNLGNPGDPFRISNCTDVS---NEQNLAFTWEMEIKPQKRDICLDY----PRKGEELTMFSCHGMGGNQKWIYNQNSHQIVHVVSKKCIDYRYNPESLEINIQKCSRKL-SQKWILE--NMNAMIANH 1895
            +N+    ++  +EI E +   + KIDW +H TI+EE  R GPGEQG    L+  +  +   L  +NG+NAL SDKIS+ RSIKD+R   CK  +Y  FLP AS I+PFHNEH STLLR+V+SI++R+P +LVKEIIL DD+S K+   + L+ YV EHFT V+I+R  KREGLIR RLLGA  A G VLIF+DSH E  IN+LPPLL+PI  +Y+T+ CPFIDVI Y +F  R QDEG RGAFDW F YKRLP L +D   P +PF NP+MAGGLFAISK WF ELGGYD GLD+WGGEQYELSFK+W CGG MVD PCSR+GH+YRKF PF+  G+G++L RN+KR+AEVWMD++ +YIY  H+  Y SLD GDLT QK +R+ LNC  F WFM+++A+DL++ YP   +P  +++G I++ +   LC D    + GD F +  C D +    EQ    TW  +I+PQ R +C D     PR    + +FSCHGM GNQ++ YN +++QI H +S  C+D   +  + E+ +  C   + +Q+W  E  N++A+ A++
Sbjct:   43 KNVKPSLEKVFEEILEKTRPVEEKIDWHDHKTIEEELKRQGPGEQGSAFKLSPEDELQKNLLYRSNGFNALVSDKISLQRSIKDIRHPHCKSKQYVKFLPTASFILPFHNEHLSTLLRSVYSIINRAPKELVKEIILTDDHSNKDECKKPLDDYVKEHFTNVKIVRAEKREGLIRTRLLGARHATGEVLIFLDSHIECNINFLPPLLEPIAQNYRTVVCPFIDVIDYENFEYRAQDEGARGAFDWEFYYKRLPLLEEDKKKPSEPFANPVMAGGLFAISKEWFWELGGYDPGLDIWGGEQYELSFKIWQCGGTMVDAPCSRIGHIYRKFAPFSNPGVGDFLGRNYKRVAEVWMDEYAEYIYS-HRPHYRSLDAGDLTSQKAIRQKLNCKPFKWFMEEVAFDLVKFYP-PVEPPAMAKGTIRN-MAIDLCIDTKFKSQGDTFSVETCADSTARAKEQQFELTWHKDIRPQGRLLCFDVSESKPRTS--VILFSCHGMQGNQRFKYNVDTNQIFHPISGLCMD--TDSTTKEVYMNPCDMTIKTQEWQFEKPNLDALKADN 594          

Query:  318 KIDWANHDTIDEENARVGPGEQGIGVYLTANENEKAKQLMETNGYNALASDKISVHRSIKDLRINKCKWLKYDNFLPPASIIIPFHNEHWSTLLRTVHSILHRSPDKLVKEIILVDDNSTKEFLGEKLEQYVSEHFTKVRILRTGKREGLIRARLLGANEANGTVLIFIDSHCEVGINWLPPLLQPIRDHYKTISCPFIDVISYNDFSLRPQDEGGRGAFDWNFDYKRLPRLSKDNAHPEKPFYNPIMAGGLFAISKLWFNELGGYDYGLDVWGGEQYELSFKVWMCGGKMVDVPCSRVGHVYRKFNPFAVVGLGNYLARNHKRIAEVWMDDWKQYIYQKHQKVYSSLDPGDLTEQKKLRKALNCTSFDWFMKQIAYDLLEKYPIQKQPENLSQGKIKSEINPHLCFDFNLGNPGDPFRISNCTD----VSNEQNLAFTWEMEIKPQKRDICLDYPRKGEE--LTMFSCHGMGGNQKWIYNQNSHQIVHVVSKKCIDYRYNPESLEINIQKC-SRKLSQKWILENMN 1877
            +IDW ++  I EE  R G GEQG  V LTA E +K   L + NG+NA ASDKIS+ R++KD+R  +CK  KY N LP ASII+PFHNEHWSTLLRT  S++ RSP  L++E+ILVDD S+KE   ++L+ YV+EH+TKVRI+R  KREGLIR RLLGA  A G VLIF+DSHCEV INWLPPLL PI    KT+ CPFIDVI Y  F+ R QDEG RGAFDW F YKRLP L +D  HP  PF +P+MAGGLFAI + WF  LGGYD GLD+WGGEQYELSFK+W CGG MVD PCSR+GHVYRKF PF   G+G+++ RN+KR+AEVWMD++ +Y+Y K +  Y +LD GDLTEQK +R  L+C SF WFM ++A+DL++ YP   +P  ++ G+++++ N   C D       + F++ +C         EQ   F+W  +I+P+ R +C D      +  + +++CHGMGGNQ++ YN  ++QI H VS +C+D   + E+LE+ +  C +   +QKW  E +N
Sbjct:   24 EIDWHDYKAIAEEQQRTGLGEQGSAVILTAEEEKKKGDLYKVNGFNAYASDKISLQRALKDIRHEQCKNKKYLNKLPTASIIVPFHNEHWSTLLRTAQSVIDRSPPHLLQEVILVDDFSSKEHCKQQLDDYVAEHYTKVRIVRAEKREGLIRTRLLGARAAKGDVLIFLDSHCEVNINWLPPLLDPIARDQKTVVCPFIDVIDYETFAYRAQDEGARGAFDWEFFYKRLPLLPEDKKHPADPFKSPVMAGGLFAIHQEWFWMLGGYDPGLDIWGGEQYELSFKIWQCGGMMVDSPCSRIGHVYRKFAPFPNPGVGDFIGRNYKRVAEVWMDEYAEYLY-KRRPHYKTLDAGDLTEQKAIRDKLHCKSFKWFMTEVAFDLVKVYP-PIEPTPMASGEVRNQAN-EKCIDTRFKGQNERFQLESCIKDGQGAGGEQQFEFSWHKDIRPKSRAVCFDAAHSAPKSPVILYNCHGMGGNQRFKYNLQTNQIFHPVSGQCLD--CDKENLEVFMNPCDADSETQKWKWEKIN 545          

Query:  279 SDEINEVSSDSQIKIDWANHDTIDEENARVGPGEQGIGVYLTANENEKAKQLMETNGYNALASDKISVHRSIKDLRINKCKWLKYDNFLPPASIIIPFHNEHWSTLLRTVHSILHRSPDKLVKEIILVDDNSTKEFLGEKLEQYVSEHFTKVRILRTGKREGLIRARLLGANEANGTVLIFIDSHCEVGINWLPPLLQPIRDHYKTISCPFIDVISYNDFSLRPQDEGGRGAFDWNFDYKRLPRLSKDNAHPEKPFYNPIMAGGLFAISKLWFNELGGYDYGLDVWGGEQYELSFKVWMCGGKMVDVPCSRVGHVYRKFNPFAVVGLGNYLARNHKRIAEVWMDDWKQYIYQKHQKVYSSLDPGDLTEQKKLRKALNCTSFDWFMKQIAYDLLEKYPIQKQPENLSQGKIKSEINPHLCFDFNLGNPGDPFRISNCT----DVSNEQNLAFTWEMEIKPQKRDICLDYPRKG--EELTMFSCHGMGGNQKWIYNQNSHQIVHVVSKKCIDYRYNPESLEINIQKC-SRKLSQKW 1859
            + + ++ + D    IDW ++  I+ E AR GPGEQG GV+L A+EN+ A  L   NG+NAL SDK+S+ RS+ D+R + C+  +Y   LP ASIIIPFH EHWSTLLRTV S +HR+P  LVKE+ILVDD S K FLG+ LE+YVS HFT VR+LR  KREGLIR R+ GA  A G VLIF+DSHCE  INWLPPLL PI ++YKT+ CPFIDVI +N F+ R QDEG RGAFDW F YKRLP L +D  HP KPF +P+MAGGLFAIS  WF ELGGYD GLD+WGGEQYELSFK+W CGG+MVD  CSR+GHVYRK+ PF   G+G+++ RN++R+AEVWMD++ +YIY +    Y S+  GDLT Q+++R+ L+C  F WFM  +A+DL  +YP   +P + + G+I+S  +  LC D         F ++ C      +S EQN  FT+  +I P  R  C D  +      + ++ CH   GNQ W  N N+ Q+ HV S+ C+D    P  LEI +  C S   +Q W
Sbjct:   58 AGDASDRTEDPNELIDWHDYKAIEAERARQGPGEQGKGVHLDASENKAADDLFRVNGFNALVSDKMSLFRSLADIRHSACQGERYRRGLPTASIIIPFHEEHWSTLLRTVVSCIHRAPRHLVKEVILVDDFSKKSFLGDPLEKYVSAHFTNVRVLRNAKREGLIRTRIFGARNATGDVLIFLDSHCECNINWLPPLLHPIANNYKTVVCPFIDVIDFNTFAYRAQDEGARGAFDWEFYYKRLPLLPEDLKHPSKPFDSPVMAGGLFAISTKWFWELGGYDPGLDIWGGEQYELSFKIWQCGGRMVDTGCSRIGHVYRKYAPFPNPGVGDFIGRNYRRVAEVWMDEYAEYIYNRRPH-YKSIPAGDLTSQREIRERLHCKPFKWFMTNVAFDLPLRYP-PVEPPSAASGEIRSAADASLCIDTRFKGGMQSFGLAKCIKGGGGLSGEQNFIFTFRKDIHPADRAFCFDVSQHAVKAPVILYQCHYQKGNQHWKINPNTGQLYHVASRLCLD--SEPARLEIFMNSCNSATQTQLW 587          

Query:  318 KIDWANHDTIDEENARVGPGEQGIGVYLTANENEKAKQLMETNGYNALASDKISVHRSIKDLRINKCKWLKYDNFLPPASIIIPFHNEHWSTLLRTVHSILHRSPDKLVKEIILVDDNSTKEFLGEKLEQYVSEHFTKVRILRTGKREGLIRARLLGANEANGTVLIFIDSHCEVGINWLPPLLQPIRDHYKTISCPFIDVISYNDFSLRPQDEGGRGAFDWNFDYKRLPRLSKDNAHPEKPFYNPIMAGGLFAISKLWFNELGGYDYGLDVWGGEQYELSFKVWMCGGKMVDVPCSRVGHVYRKFNPFAVVGLGNYLARNHKRIAEVWMDDWKQYIYQKHQKVYSSLDPGDLTEQKKLRKALNCTSFDWFMKQIAYDLLEKYPIQKQPENLSQGKIKSEINPHLCFDFNLGNPGDPFRISNC----TDVSNEQNLAFTWEMEIKPQKRDICLDYPRKGEE--LTMFSCHGMGGNQKWIYNQNSHQIVHVVSKKCIDYRYNPESLEINIQKC-SRKLSQKWILENMNAMIANHL 1898
            KIDW N+D I  E+ R GPGE G  V +   EN +  +L +TNG+NALASDKI++ R++KD+R   CK  +Y   LP  S+I+PFHNEHW+TLLRT  S+L RSP  L+KEIILVDD STK+FL  KL+ Y+ EH  KVR++R  KREGLIRARLLGA  A G+VLIF+DSH E  +NWLPPLL+PI ++Y+T +CPFID+I Y  F  R QDEG RGAFDW   YKRLP L  D  +P +PF +P+MAGGLFAIS+ +F ELGGYD GLDVWGGEQYELSFK+W CGG MVDVPCSR+GH+YRKF PF+  G+G+++ RN+KR+AEVWMD++ +++Y K    Y +++ G+L++Q+KLR  L C SF WFM ++A+DL+++YP   +P N + G+I++ I  + C D       + F +  C    T+ + EQ+   TW  +I+P+ R +C D      +  + +++CH   GNQ+W Y   + Q+ H VS KC D   +PE  EI +  C S KLSQ+W+ E+ N+ +   L
Sbjct:   58 KIDWHNYDLIARESERTGPGEHGKSVIIPTEENNEKDELYKTNGFNALASDKIALDRAVKDIRHEGCKKKRYFENLPTVSVIVPFHNEHWTTLLRTAMSVLVRSPPALIKEIILVDDFSTKDFLKGKLDDYIKEHMQKVRVIRAPKREGLIRARLLGAQAATGSVLIFLDSHSEPNVNWLPPLLEPIAENYRTTTCPFIDIIDYETFEYRAQDEGARGAFDWELYYKRLPLLPADIKNPTEPFKSPVMAGGLFAISRKFFWELGGYDEGLDVWGGEQYELSFKIWQCGGMMVDVPCSRIGHIYRKFAPFSNPGVGDFVGRNYKRVAEVWMDEYAEFLYNKRPH-YRNIETGNLSKQRKLRDTLKCKSFKWFMTEVAFDLMDRYP-PVEPPNYAWGEIRN-IASNQCMDTRFKGQNERFLLEPCIKDNTENNGEQSFELTWHKDIRPKNRAVCFDVSTSDNKSPIVLYNCHNSQGNQQWRYTVETKQLFHPVSGKCAD--CDPERREIFVSDCDSSKLSQQWLFEHFNSTLLAKL 586          

Query:  303 SDSQIKIDWANHDTIDEENARVGPGEQGIGVYLTANENEKAKQLMETNGYNALASDKISVHRSIKDLRINKCKWLKYDNFLPPASIIIPFHNEHWSTLLRTVHSILHRSPDKLVKEIILVDDNSTKEFLGEKLEQYVSEHFTKVRILRTGKREGLIRARLLGANEANGTVLIFIDSHCEVGINWLPPLLQPIRDHYKTISCPFIDVISYNDFSLRPQ-DEGGRGAFDWNFDYKRLP-RLSKDNAHPEKPFYNPIMAGGLFAISKLWFNELGGYDYGLDVWGGEQYELSFKVWMCGGKMVDVPCSRVGHVYRKFNPFAVVGLGNYLARNHKRIAEVWMDDWKQYIYQKHQKVYSSLDPGDLTEQKKLRKALNCTSFDWFMKQIAYDLLEKYPIQKQPENLSQGKIKSEINPHLCFDFNLGNPGDPFRISNCTDV------SNEQNLAFTWEMEIKP----QKRDICLDYPRKGEELTMFSCHGMGGNQKWIYNQNSHQIVHVVSKKCIDYRYNPESLEINIQKCS-RKLSQKWILENMNAMIAN 1892
            +D   + DW ++++I  +  RVG GE G    L   E+E    + + NG+N   S+ I++ RS+ D+R   CK   Y   LP  SIIIPFHNE WS+LLRT+HSI++R+PD L+ EIILVDD S ++ LG +LE Y+S  F KVRI+RT KREGLIR RLLGA+ A G VL F+DSHCE  INWLPPLL  I  + +TI CP IDVI +N F    Q  +  RGAFDW   YKR+P  L    + P  P+ +P+MAGGLFA+ + WF ELGGYD GL++WGGEQYE+SFKVWMCGG M DVPCSRVGH+YRK+ P+ V   G  LARN KR+AE WMD++ +YIYQ+  + Y  L  GDLT QK+LRK L C  F W+M  +A+DL + YP   +P   + G+I++  +  LC D   G+ G   R+  C         ++EQ   F W  +I+P      R  C D   +   +T++ CHGM GNQ W Y ++   + H+VS  C+D   +P    I + KC+ +  +Q+W+ + +N  I +
Sbjct:   60 TDGLRRRDWHDNESIRRDELRVGKGEHGKPYPLA--EDECDDSVYKENGFNIYVSNNIALDRSLPDIRHPNCKQKLYLENLPNTSIIIPFHNEGWSSLLRTIHSIVNRTPDHLIAEIILVDDYSDRDHLGARLEDYMSR-FPKVRIVRTKKREGLIRTRLLGASVAKGEVLTFLDSHCETNINWLPPLLDQIAQNPRTIVCPMIDVIDHNHFGYEAQAGDAMRGAFDWEMYYKRIPIPLELQGSDPSNPYESPVMAGGLFAVRRQWFWELGGYDTGLEIWGGEQYEISFKVWMCGGSMYDVPCSRVGHIYRKYVPYKVPS-GTSLARNLKRVAETWMDEFAEYIYQRRPE-YRHLSTGDLTAQKELRKHLKCKDFKWYMNTVAWDLPKYYP-PVEPLPAAWGEIRNAAS-GLCVDSKHGSTGTELRLDTCLKEGAERTWAHEQIFTFGWREDIRPGDPLHTRKFCFDAISQSSPVTLYDCHGMRGNQHWSYRKDK-SLYHLVSSGCMD--CSPADKRIFMNKCNPQSETQQWLFQRVNTTILD 592          

Query:  408 NENEKAKQLMETNGYNALASDKISVHRSIKDLRINKCKWLKYDNFLPPASIIIPFHNEHWSTLLRTVHSILHRSPDKLVKEIILVDDNSTKEFLGEKLEQYVSEHFTKVRILRTGKREGLIRARLLGANEANGTVLIFIDSHCEVGINWLPPLLQPIRDHYKTISCPFIDVISYNDFSLRPQ-DEGGRGAFDWNFDYKRLP---RLSKDNAHPEKPFYNPIMAGGLFAISKLWFNELGGYDYGLDVWGGEQYELSFKVWMCGGKMVDVPCSRVGHVYRKFNPFAVVGLGNYLARNHKRIAEVWMDDWKQYIYQKHQKVYSSLDPGDLTEQKKLRKALNCTSFDWFMKQIAYDLLEKYPIQKQPENLSQGKIKSEINPHLCFDFNLGNPGDPFRISNC------TDVSNEQNLAFTWEMEIKP----QKRDICLDYPRKGEELTMFSCHGMGGNQKWIYNQNSHQIVHVVSKKCIDYRYNPESLEINIQKCSRKL-SQKWILENMNAMIANHL 1898
             + ++  Q    NG+N   S++IS++RS+ D+R   CK   Y   LP  SIIIPFHNE WS+LLRTVHSIL+RSP +L+ EIILVDD S +E L   LE Y+     KVRILRT KREGLIR RLLGA  A G V+ F+DSHCE  +NWLPPLL  I  + K I CP IDVI +++F    Q  +  RGAFDW   YKR+P    L KD+  P +PF +P+MAGGLFA+ + WF ELGGYD GL++WGGEQYE+SFKVWMCGG+M D+PCSRVGH+YRK+ P+ V G G  LARN KR+AEVWMD++ +YIYQ+  + Y  L  GD+T QK+LR  LNC +F WFM  +A+DL + YP   +P   + G++++ +   LC +    + G P R+  C      T  S+ Q   F W  +I+       + +C D       +T++ CHGM GNQ W Y ++   + H +S  CID  +NP    + +  C   + +Q+W+ E  N+ + +  
Sbjct:    2 TDADRVDQAYRENGFNIYVSNRISLNRSLPDIRHPNCKLKLYSERLPNTSIIIPFHNEGWSSLLRTVHSILNRSPPELIAEIILVDDFSDREHLKASLEDYMVR-MPKVRILRTKKREGLIRTRLLGAAAAKGEVITFLDSHCEANVNWLPPLLDRIAQNRKAIVCPMIDVIDHDNFGYETQAGDAMRGAFDWEMYYKRIPIPAELQKDD--PSEPFESPVMAGGLFAVDRKWFWELGGYDTGLEIWGGEQYEISFKVWMCGGRMEDIPCSRVGHIYRKYVPYKVPG-GVSLARNLKRVAEVWMDEYAEYIYQRRPE-YRHLSAGDVTTQKELRARLNCKNFKWFMTDVAWDLPKHYP-PVEPPAAAWGELRN-VGSGLCMESKHFSSGTPLRMEVCVKGRGETAWSHGQVFTFGWREDIRVGDPLHTKKVCFDAISHNSPVTLYDCHGMKGNQLWRYRKDK-TLYHPISNSCID--HNPNEKRVFMNSCDASIATQQWVFERTNSTVLDQF 503          

Query:  369 GPGEQGIGVYLTANENEKAKQLMETNGYNALASDKISVHRSIKDLRINKCKWLKYDNFLPPASIIIPFHNEHWSTLLRTVHSILHRSPDKLVKEIILVDDNSTKEFLGEKLEQYVSEHFTKVRILRTGKREGLIRARLLGANEANGTVLIFIDSHCEVGINWLPPLLQPIRDHYKTISCPFIDVISYNDFSLRPQDEGGRGAFDW--NFDYKRLPRLSKDNAHPEK--PFYNPIMAGGLFAISKLWFNELGGYDYGLDVWGGEQYELSFKVWMCGGKMVDVPCSRVGHVYRKFNPFAVV-GLGNYLARNHKRIAEVWMDDWKQYIYQKHQKVYSSLDPGDLTEQKKLRKALNCTSFDWFMKQIAYDLLEKYPIQKQPEN-LSQGKIKSEINPHLCFDFNLGNP-GDPFRISNCTDVSNEQNLAFTWEMEIKPQKRDICLDYPRKGEELTMFSCHGMGGNQKWIYNQNSHQIVHVVSKKCIDYRYNPESLEINIQKCSRKLSQKWILENMNAMI 1886
            GPGE G  V +  ++ EK K+L + N +N +ASD I+++RS+ D+R++ CK   Y + LP  SI+I FHNE WSTLLRTVHS+++RSP  L+ EI+LVDD S ++FL +KLE YV      VRILR  +R GLIRARL GA    G V+ F+D+HCE  + WL PLL  I++  K + CP IDVIS   F      +   G F+W  NF +  +P+   D    ++  P   P MAGGLF+I + +F E+G YD G+D+WGGE  E+SF++W CGG +  V CS VGHV+RK  P++   G G  + +N++R+AEVWMD++K + Y     V   +D GD++ +K LR+AL C  F W+++ I       YP  + P    S G+I++ +  + C D N+G    +     NC  +   Q  ++T + EI+    D+CLD  R    + M  CH M GNQ + Y+     ++HV S +C+D     + +   ++ C+   SQ+W+L NM   I
Sbjct:   56 GPGEMGKAVIIPKDDQEKMKELFKINQFNLMASDMIALNRSLPDVRLDGCKTKVYPDDLPNTSIVIVFHNEAWSTLLRTVHSVINRSPRHLLVEILLVDDASERDFLKKKLEDYVKTLEVPVRILRMEQRSGLIRARLRGAAATRGQVITFLDAHCECTVGWLEPLLSRIKEDRKAVVCPIIDVISDETFEYMAGSDMTYGGFNWKLNFRWYPVPQREMDRRKGDRTLPVRTPTMAGGLFSIDRSYFEEIGTYDPGMDIWGGENLEMSFRIWQCGGSLEIVTCSHVGHVFRKATPYSFPGGTGQVINKNNRRLAEVWMDEFKDFFYIISPGVV-RVDYGDVSARKALREALQCKPFSWYLENI-------YPDSQIPRRYFSLGEIRN-VETNQCVD-NMGRKENEKVGFFNCHGMGGNQVFSYTADKEIRTD--DLCLDVSRLNGPVVMLKCHHMKGNQMFEYDAERLTLLHVNSNQCLDMPSEEDKMVPTLRDCNGSRSQQWLLRNMTLSI 556          

Query:  369 GPGEQGIGVYLTANENEKAKQLMETNGYNALASDKISVHRSIKDLRINKCKWLKYDNFLPPASIIIPFHNEHWSTLLRTVHSILHRSPDKLVKEIILVDDNSTKEFLGEKLEQYVSEHFTKVRILRTGKREGLIRARLLGANEANGTVLIFIDSHCEVGINWLPPLLQPIRDHYKTISCPFIDVISYNDFSLRPQDEGGRGAFDW--NFDYKRLPRLSKDNAHPEK--PFYNPIMAGGLFAISKLWFNELGGYDYGLDVWGGEQYELSFKVWMCGGKMVDVPCSRVGHVYRKFNPFAVV-GLGNYLARNHKRIAEVWMDDWKQYIYQKHQKVYSSLDPGDLTEQKKLRKALNCTSFDWFMKQIAYDLLEKYPIQKQPEN-LSQGKIKSEINPHLCFDFNLGNPGDPFRISNCTDVSNEQNLAFTWEMEIKPQKRDICLDYPRKGEELTMFSCHGMGGNQKWIYNQNSHQIVHVVSKKCIDYRYNPESLEINIQKCSRKLSQKWILENMN 1877
            GPGE G  V +   ++EK K++ + N +N +AS+ I+++RS+ D+R+  CK   Y + LP  S++I FHNE W+TLLRTVHS+++RSP  L++E++LVDD S ++FL  KLEQYV +    VRI+R  +R GLIRARL GA+ + G V+ F+D+HCE  + WL PLL  I+   KT+ CP IDVIS + F      +   G F+W  NF +  +P+   D    ++  P   P MAGGLF+I + +F E+G YD G+D+WGGE  E+SF++W CGG +  V CS VGHV+RK  P+    G G  + +N++R+AEVWMD++K + Y     V + +D GD+  +  LR+ L C  F W+++ +       YP  + P +  S G+I++ +  + C D       +   I NC  +   Q  ++T   EI+    D+CLD  +    + M  CH + GNQ W Y+     +VHV S +C+D     +S   +++ C+   SQ+W+L N+ 
Sbjct:   55 GPGEMGKPVVIPKEQHEKMKEMFKINQFNLMASEMIALNRSLPDVRLEGCKNKVYPDDLPRTSVVIVFHNEAWTTLLRTVHSVINRSPRHLLEEVVLVDDASERDFLKRKLEQYVRKLEVPVRIVRMEQRSGLIRARLKGASLSTGQVITFLDAHCECTMGWLEPLLSRIKQDKKTVVCPIIDVISDDTFEYMAGSDMTYGGFNWKLNFRWYPVPQREMDRRKGDRTLPVRTPTMAGGLFSIDRDYFQEIGTYDAGMDIWGGENLEISFRIWQCGGTLEIVTCSHVGHVFRKATPYTFPGGTGQIINKNNRRLAEVWMDEFKNFFYIISPGV-TKVDYGDIATRASLRQKLQCKPFSWYLENV-------YPDSQIPRHYYSLGEIRN-VETNQCLDNMARKENEKVGIFNCHGMGGNQVFSYTANKEIRTD--DLCLDVSKLNGPVMMLKCHHLKGNQLWDYDPLKLSLVHVNSNQCLDKASEDDSQVPSVRDCTGSRSQQWLLRNVT 552          

Query:  369 GPGEQGIGVYLTANENEKAKQLMETNGYNALASDKISVHRSIKDLRINKCKWLKYDNFLPPASIIIPFHNEHWSTLLRTVHSILHRSPDKLVKEIILVDDNSTKEFLGEKLEQYVSEHFTKVRILRTGKREGLIRARLLGANEANGTVLIFIDSHCEVGINWLPPLLQPIRDHYKTISCPFIDVISYNDFSLRPQDEGGRGAFDW--NFDYKRLPRLSKDNAHPEK--PFYNPIMAGGLFAISKLWFNELGGYDYGLDVWGGEQYELSFKVWMCGGKMVDVPCSRVGHVYRKFNPFAVV-GLGNYLARNHKRIAEVWMDDWKQYIYQKHQKVYSSLDPGDLTEQKKLRKALNCTSFDWFMKQIAYDLLEKYPIQKQPEN-LSQGKIKSEINPHLCFDFNLGNP-GDPFRISNCTDVSNEQNLAFTWEMEIKPQKRDICLDYPRKGEELTMFSCHGMGGNQKWIYNQNSHQIVHVVSKKCI------DYRYNPESLEINIQKCSRKLSQKWILENMNAM 1883
            GPGE G  V +  ++ EK K+L + N +N +ASD I+++RS+ D+R++ CK   Y + LP  SI+I FHNE WSTLLRTVHS+++RSP  L+ EI+LVDD S ++FL +KLE YV      VRILR  +R GLIRARL GA    G V+ F+D+HCE  + WL PLL  I++  K + CP IDVIS   F      +   G F+W  NF +  +P+   D    ++  P   P MAGGLF+I + +F E+G YD G+D+WGGE  E+SF++W CGG +  V CS VGHV+RK  P++   G G  + +N++R+AEVWMD++K + Y     V   +D GD++ +K LR+AL C  F W+++ I       YP  + P    S G+I++ +  + C D N+G    +     NC  +   Q  ++T + EI+    D+CLD  R    + M  CH M GNQ + Y+      +H++++ C+      D  Y P      ++ C     Q W+L N   +
Sbjct:   56 GPGEMGKAVIIPKDDQEKMKELFKINQFNLMASDMIALNRSLPDVRLDGCKTKVYPDDLPNTSIVIVFHNEAWSTLLRTVHSVINRSPRHLLVEILLVDDASERDFLKKKLEDYVKTLEVPVRILRMEQRSGLIRARLRGAAATRGQVITFLDAHCECTVGWLEPLLSRIKEDRKAVVCPIIDVISDETFEYMAGSDMTYGGFNWKLNFRWYPVPQREMDRRKGDRTLPVRTPTMAGGLFSIDRSYFEEIGTYDPGMDIWGGENLEMSFRIWQCGGSLEIVTCSHVGHVFRKATPYSFPGGTGQVINKNNRRLAEVWMDEFKDFFYIISPGVV-RVDYGDVSARKALREALQCKPFSWYLENI-------YPDSQIPRRYFSLGEIRN-VETNQCVD-NMGRKENEKVGFFNCHGMGGNQVFSYTADKEIRTD--DLCLDVSRLNGPVVMLKCHHMKGNQMFEYDAEKGTFMHIITQSCLTISRLEDGTYGP-----TVEYCDDSPLQTWVLRNYTRL 556          

Query:  516 CKWLKYDNFLPPASIIIPFHNEHWSTLLRTVHSILHRSPDKLVKEIILVDDNSTKEFLGEKLEQYVSEHFTKVRILRTGKREGLIRARLLGANEANGTVLIFIDSHCEVGINWLPPLLQPIRDHYKTISCPFIDVISYNDFSLRPQDEGGRGAFDW--NFDYKRLPRLSKDNAHPEK--PFYNPIMAGGLFAISKLWFNELGGYDYGLDVWGGEQYELSFKVWMCGGKMVDVPCSRVGHVYRKFNPFAVV-GLGNYLARNHKRIAEVWMDDWKQYIYQKHQKVYSSLDPGDLTEQKKLRKALNCTSFDWFMKQIAYDLLEKYPIQKQPEN-LSQGKIKSEINPHLCFDFNLGNP-GDPFRISNCTDVSNEQNLAFTWEMEIKPQKRDICLDYPRKGEELTMFSCHGMGGNQKWIYNQNSHQIV--HVVSKKCIDYRYNPESLEINIQKCSRKLSQKWILENMNA 1880
            CK   Y + LP  S++I FHNE WSTLLRTVHSI+ RSP  +++EIILVDD S ++FL   LE+Y S+    V I+R   R GLIRARL GA  + G V+ F+D+HCE    WL PLL  I+   K + CP IDVIS   F      +   G F+W  NF +  +P+   D    ++  P  +P MAGGLFAI + +F E+G YD G+D+WGGE  E+SF++W CGG +  V CS VGHV+RK  P+    G G  + +N++R+AEVWMD++K + Y     V + ++ GD++++K LR  L C  F WF++ +       YP  + P +  S G++++ +  + C D N+G    +   I NC  +   Q  ++T + E++    D+CLD  R    + M  CH M GNQ W Y+Q   +++  H  S +C+D     +     +++C    SQ+WIL NM  
Sbjct:    1 CKTKVYPDGLPKTSVVIVFHNEAWSTLLRTVHSIIGRSPRHMLEEIILVDDASERDFLKSPLEEYASKLPVPVHIVRMESRSGLIRARLRGAAVSRGQVITFLDAHCECTTGWLEPLLARIKADRKNVVCPIIDVISDETFEYLAGSDMTYGGFNWKLNFRWYPVPQSEMDRRKGDRTIPVRSPTMAGGLFAIDRDYFQEIGTYDAGMDIWGGENLEMSFRIWQCGGTLEIVTCSHVGHVFRKATPYTFPGGTGQVINKNNRRLAEVWMDNFKDFFYIISPGV-TKVEYGDVSQRKALRDRLKCKPFSWFLENV-------YPNSQIPRHYYSLGEVRN-VETNQCLD-NMGRKENEKIGIFNCHSMGGNQVFSYTADKELRTD--DLCLDVSRMNGPVLMLKCHHMKGNQLWDYDQQMQKLIMRHTNSNQCLDKATEQDRQVPTMRECDGGRSQQWILRNMTV 452          

Query:  375 GEQGIGVYLTANENEKAKQLMETNGY--NALASDKISVHRSIKDLRINKCKWLKYD-NFLPPASIIIPFHNEHWSTLLRTVHSILHRSPDKLVKEIILVDDNSTKEFLGEKLEQYVSEHFTKVRILRTGKREGLIRARLLGANEANGTVLIFIDSHCEVGINWLPPLLQPIRDHYKTISCPFIDVISYNDFS-LRPQDEGGRGAFDWN--FDYKRLP-RLSKDNAHPEKPFYNPIMAGGLFAISKLWFNELGGYDYGLDVWGGEQYELSFKVWMCGGKMVDVPCSRVGHVYRKFNPFAVVGLGNYLARNHKRIAEVWMDDWKQYIYQKHQKVYSSLDP-GDLTEQKKLRKALNCTSFDWFMKQIAYDLLEKYPIQKQPENLSQ--GKIKSEINPHLCFDFNLGN----PGDPFRISNCTDVSNEQNLAFTWEMEIKPQKR--DICLDYPRKGEELTMFSCHG----MGGNQKWIYNQNSHQIVHVVSKKCIDYRYNPESLEIN-IQKCSRKLSQKWILE 1868
            GE G  V L     EK K+    N +  N   SD+IS+HR + +     C+  KY+   LP  S++I F+NE WSTLLRTVHS+L  SPD L+ EIILVDD S +E L ++LEQY++    KVR++R  KREGL+RARLLGA  A G VL F+D HCE  + WL PLL+ I +    + CP IDVI +N F  +    E   G FDW   F +  +P    K    P     +P MAGGLFA+SK +F+ LG YD G++VWGGE  E SF++W CGG +   PCS VGHV+ K  P++       LA N  R AEVWMD +K+  Y  H+  ++ ++P GD+TE++ LR+ L C +F WF++ +       YP    PE+     G +K+    + CFD+N  +     G    +  C  +   Q   +T E EI+   R  + C       + LTM+ CH     +  NQK+ + ++   I H++++KC++    P S  +  ++ C     Q+W+ +
Sbjct:   28 GEMGKAVRLNLEGEEKRKEEESINKHQINIYVSDRISLHRQLPEKWNPLCREKKYNYRQLPTTSVVIAFYNEAWSTLLRTVHSVLETSPDALLNEIILVDDYSDREHLRDRLEQYIAT-LRKVRLVRARKREGLVRARLLGAGVATGDVLTFLDCHCECHVGWLEPLLERIAEEESAVVCPVIDVIEWNTFEYMGNAGEPQIGGFDWRLVFTWHTVPGHEQKRRKSPIDVIRSPTMAGGLFAVSKKYFDYLGTYDTGMEVWGGENLEFSFRIWQCGGTLEVHPCSHVGHVFPKQAPYS---RSKALA-NSVRAAEVWMDGYKELYY--HRNPHARMEPFGDVTERRNLRERLQCKTFKWFLENV-------YPDIHVPEDRPGKFGMLKNRGLSNYCFDYNPPDENQVTGQRIILYGCHGMGQNQFFEYTSEQEIRYNTRQPEACAAVDNGMDYLTMYYCHSKNSPVTENQKFDFREDG-SIFHILTQKCLEAVEQPNSGPLPLLRTCDGNTRQRWLFK 531          

Query:  405 ANENEKAKQL-METNGYNALASDKISVHRSIKDLRINKCKWLKYDNFLPPASIIIPFHNEHWSTLLRTVHSILHRSPDKLVKEIILVDDNSTKEFLGEKLEQYVSEHFTK-VRILRTGKREGLIRARLLGANEANGTVLIFIDSHCEVGINWLPPLLQPIRDHYKTISCPFIDVISYNDFSLRPQDEGGRGAFDWNFDYKRLPRLSKDNAHPE---KPFYNPIMAGGLFAISKLWFNELGGYDYGLDVWGGEQYELSFKVWMCGGKMVDVPCSRVGHVYRKFNPFAVVGLGNYLARNHKRIAEVWMDDWK-QYIYQKHQKVYSSLDPGDLTEQKKLRKALNCTSFDWFMKQIAYDLLEKYP---------IQKQPENLSQGKIKS-EINPHLCFDFNLGNPGDPFRISNCTDVSNEQNLAFTWEMEIKPQKRDICLDYPRKGEELT--MFSCHGMGGNQKWIYNQNSHQIVHVVSKKCIDYRYNPE-SLEINIQKCSRKLSQKW 1859
            + E+++ + L  + + +N L S+++  HR+I D R  +C    Y   LP AS++I F+NE  S LLRTVHS+  R+P  L+ E++LVDD S    L E LE+ + E F K V+++R  KREGLIR R++GAN A G VL+F+DSHCEV + WL PLL  + ++  T+ CP ID+++ + F L       RG F+W   ++  P  S   + P+    P  +P MAGGLFA+ + +FN+LG YD G+D+WGGE  E+SF++WMCGG +  +PCSR+GH++RK  P+      + ++RN  R+A VW+D++K QY+  + +      + GD++E+K LR+ L C  F W+++ +  ++    P         + K+P+ + +G+++  +    L    +    G    +  C     EQ   +    E++     +CLD P      +  +  CHG GG+Q+W   +  +++  V   +C+  +   +    + ++ C+    Q+W
Sbjct:    5 SREDQETRDLGYQKHAFNLLISNRLDPHRTIPDTRHPRCATKSYPAQLPTASVVICFYNEAVSALLRTVHSVTERTPPALLHEVLLVDDFSDLVDLREGLEKELKEKFPKKVKLVRNEKREGLIRGRMVGANHATGDVLVFLDSHCEVNVAWLEPLLARVAENPSTVVCPIIDIVNPDTF-LYSASPLVRGGFNWGLHFRWDPVPSSLLSGPDGEMAPIKSPTMAGGLFAMDRKYFNKLGQYDGGMDIWGGENLEISFRIWMCGGSLEIIPCSRIGHIFRKRRPYGSPAGADTMSRNSLRLAHVWLDEYKEQYLALRPE--LREREYGDVSERKALRERLGCRPFRWYLQNVYPEIEVGRPQLPQAVLSKMHKRPKPVQRGRLRHLQTGKCLVAHNDPSEKGGLVVVRPCDSGDIEQVWVYNEGQELQ-LANLLCLDMPEMEPRASPRLMKCHGSGGSQQWTMGK-FNRLYQVSLGQCLQVKSMTDVKGRVVMEICNGSEQQQW 503          

Query:  372 PGEQGIGVYLTA---------NENEKAKQLMETNGYNALASDKISVHRSIKDLRINKCKWLKYD-NFLPPASIIIPFHNEHWSTLLRTVHSILHRSPDKLVKEIILVDDNSTKEFLGEKLEQYVSEHFTKVRILRTGKREGLIRARLLGANEANGTVLIFIDSHCEVGINWLPPLLQPIRDHYKTISCPFIDVISYNDFSLRPQ-DEGGRGAFDW--NFDYKRLPRLSKDN-AHPEKPFYNPIMAGGLFAISKLWFNELGGYDYGLDVWGGEQYELSFKVWMCGGKMVDVPCSRVGHVYRKFNPFAVVGLGNYLARNHKRIAEVWMDDWKQYIYQKHQKVYSSLDPGDLTEQKKLRKALNCTSFDWFMKQIAYDLLEKYPIQKQPENLS--QGKIKSEINPHLCFDFNLGNPGDPFRISNCTDVSNEQNLAFTWEMEIKPQKRDICLDYPRKGEELTMFSCHGMGGNQKWIYNQNSHQIVHVVSKKCIDYR 1796
            P E+ +G +  A         +E +  ++ +E    N   SD+IS+HR I D R+ +CK  K+D   LP  S++I F+NE WSTLLRTVHS+L  SP  L++EIILVDD S + +L   LE Y+S    +VR++RT +REGL+RARLLGA  A G VL F+D HCE    W+ PLLQ I +    + CP ID I +N F    Q  E   G FDW   F +  +P   +   A   +P  +P MAGGLFA+SK +F+ +G YD G++VWGGE  ELSF+VW CGG +   PCS VGHV+ K  P+          +N  R AEVWMD +K++ Y ++         GDL+E+K LR+ L C SF+W++K I       YP    PE+     G I+++     C D+N  +       +N T                              G  L+++ CHG GGNQ + Y        +  ++ C + R
Sbjct:   72 PDERALGEWAKAARLNLPEGSSERKLEEESIERYALNIYLSDRISLHRHIPDGRMYECKAQKFDYRRLPTTSVVIAFYNEAWSTLLRTVHSVLESSPAVLLREIILVDDFSDRAYLKSPLEDYIST-LERVRLVRTTQREGLVRARLLGATHATGQVLTFLDCHCECVPGWIEPLLQRIWEKETAVVCPVIDTIDWNTFEFYMQTSEPAIGGFDWRLTFQWHGVPEHERSRRASRIEPIQSPTMAGGLFAVSKKYFDHIGTYDQGMEVWGGENLELSFRVWQCGGSLEVHPCSHVGHVFPKKAPYP----RPRFLQNTVRAAEVWMDSYKEHFYNRNPPGRKE-KYGDLSERKTLREKLGCKSFEWYLKNI-------YPDLHVPEDRPGFHGAIQNKGIQSECIDYNAPD-------NNPT------------------------------GAMLSLYPCHGQGGNQFFEYTTRKDLRFNSATELCAEVR 512          

Query:  399 LTANENEKAKQLMETNGYNALASDKISVHRSI-KDLRINKCKWLKYDNF--LPPASIIIPFHNEHWSTLLRTVHSILHRSPDKLVKEIILVDDNSTKEFLGEKLEQYVSEHFTKVRILRTGKREGLIRARLLGANEANGTVLIFIDSHCEVGINWLPPLLQPIRDHYKTISCPFIDVISYNDFSL-RPQDEG---GRGAFDW--NFDYKRLPR----LSKDNAHPEKPFYNPIMAGGLFAISKLWFNELGGYDYGLDVWGGEQYELSFKVWMCGGKMVDVPCSRVGHVYRKFNPFAVVGLGNYLARNHKRIAEVWMDDWKQYIYQKHQK---VYSSLDPGDLTEQKKLRKALNCTSFDWFMKQIAYDLLEKYPIQKQPENLSQGKIKSEINPHLCFDFNLGNPGDPFRISNCTDVSNEQNLAFTWEMEIKPQKRDICLDYPRKGEELTMFSCHGMGGNQKWIYNQNSHQIVHVVSKKCIDYRYNPESLE 1817
            L+  E    ++ ME + +N  ASDK+S+HR +  D R  +C   K+     +P  S+II FHNE WSTLLRTVHS+++ SP  L+KEIILVDD S  ++L   L++YV + F  V+++R  +R+GLI ARLLGA+ A G VL F+D+HCE    WL PLL  IR +  ++  P I  I  N F + +P        RG FDW   F ++ +P     L KD  +P +   +P  AGGLF+ISK +F  LG YD  +++WGGE  E+SF+VW CGG++  +PCS VGHV+R  +P       + + RN  R+AEVWMDD+K   Y+++ +   +  +   GD+T +K+LR  L C +F W++  +       YP    P          +++P++         G      NC D  + QN                       G+ L ++ CHGMGGNQ + Y+       +V  + C+        LE
Sbjct:  133 LSPEEKAIKEKGMEKHCFNVYASDKVSLHRDLGPDTRPPECIEQKFKRCPSMPSTSVIIVFHNEAWSTLLRTVHSVMYTSPSVLLKEIILVDDASVDDYLKGPLDEYVKQ-FGIVKVVRQQERKGLITARLLGASVAQGEVLTFLDAHCECFNGWLEPLLARIRQNETSVVSPDISTIDMNTFEVNKPSAYSPAHNRGNFDWGLTFGWEPIPSRERTLRKDQTYPIR---SPTFAGGLFSISKKYFEYLGTYDDQMEIWGGENIEMSFRVWQCGGQLEIIPCSIVGHVFRTKSPHTFPQGVSVITRNLVRLAEVWMDDYKDIFYRRNSQAAEIVKNKAYGDVTWRKRLRDKLQCKNFTWYLTNV-------YPEMFVP----------DLHPNIFGAIKNKAKG------NCLDTGSFQN---------------------EVGKPLILYPCHGMGGNQYFEYSSQKELRHNVAKEMCLHAAMGAMHLE 573          

Query:  369 GPGEQGIGVYLTANENEKAKQLMETNGYNALASDKISVHRSIKDLRINKCKWLKYDNFLPPASIIIPFHNEHWSTLLRTVHSILHRSPDKLVKEIILVDDNSTKEFLGEKLEQYVSEHFTKVRILRTGKREGLIRARLLGANEANGTVLIFIDSHCEVGINWLPPLLQPIRDHYKTISCPFIDVISYNDFSLRPQDEGGRGAFDWNFDYKR---LPRLSKDNAHPEKPFYNPIMAGGLFAISKLWFNELGGYDYGLDVWGGEQYELSFKVWMCGGKMVDVPCSRVGHVYRKFNPFAVVGLGNYLARNHKRIAEVWMDDWKQYIYQKHQKVYSSLDPGDLTEQKKLRKALNCTSFDWFMKQIAYDLLEKYPIQKQPENLSQGKIKSEINPHLCFDFNLGNPGDPFRISNCTDVSNEQNLAFTWEMEIKPQKRDICLD----YPRKGEELTMFSCHGMGGNQKWIYNQ 1745
            GPGE G  V   A +  K        G+N   SD+IS+ R+I D R   CK   Y   LP AS++I FHNE WSTL+RTVH++L RSP  +++EI++VDD S K+FL +KL+ Y ++   K++I+RT +R GLI+AR++GAN A G V+IF+D+HCE    WLPPLL+ I  + +T  CP ID I +  F  +P D   RG F+W FDYK     P        P +   +P+MAGGLFAI++ +F+ELG YD G+ +WGGEQYE+SFK+W CGG++ ++PCSRVGHVYR   P+        L  N +R+AEVWMD++K ++Y K  ++  S+D GD++++  LRK L C SF W+++ +A D + K  +    +  +QGK       ++C D ++G       +++C ++   Q   +T+  E++    + C D    +P  G ++  F CH M GNQ++++ +
Sbjct:    1 GPGENGEPVETKAEDESKKDAAYSEFGFNQFVSDQISLERTISDTRHQACKQRSYPINLPKASVVIVFHNEGWSTLMRTVHTVLLRSPPHMLQEIVMVDDFSNKDFLKQKLDDY-TKKLGKIKIVRTKERVGLIKARVIGANNAVGEVVIFLDAHCECNKGWLPPLLERIALNRRTAVCPTIDFIDHKTFQYKPMDPYIRGTFNWRFDYKERAVRPEEMAKRRDPTQEVKSPVMAGGLFAINREFFSELGQYDPGMFIWGGEQYEISFKLWQCGGQLENIPCSRVGHVYRHHVPYTYPKHDATLV-NFRRVAEVWMDEYKDWLYDKRPEI-KSVDYGDISDRIALRKRLKCKSFKWYLENVANDTV-KTKLCACFQVRNQGK-------NMCLD-SMGRKDGHVGLASCHNMGGNQAFQYTYIRELRTD--ETCFDVHESFP--GAKVHFFPCHEMKGNQEFLFTE 450          

Query:  387 IGVYLTANENEKAKQLMETNGYNALASDKISVHRSIKDLRINKCKWLKYDNFLPPASIIIPFHNEHWSTLLRTVHSILHRSPDKLVKEIILVDDNSTKEFLGEKLEQYVSEHFTKVRILRTGKREGLIRARLLGANEANGTVLIFIDSHCEVGINWLPPLLQPIRDHYKTISCPFIDVISYNDFSLRPQDEGGRGAFDWNFDYKRLPRLSKDNAHPE---KPFYNPIMAGGLFAISKLWFNELGGYDYGLDVWGGEQYELSFKVWMCGGKMVDVPCSRVGHVYRKFNPFAVVGLGNYLARNHKRIAEVWMDDWKQYIYQKHQKVYSSLDPGDLTEQKKLRKALNCTSFDWFMKQIAYDLLEK--------YPIQKQPENLS-QGKIKSEINPHLCFD--FNLGNPGDPFRISNCTDVSN-EQNLAFTWEM----EIKPQKRDICLDYP--RKGEELTMFSCHGMGGNQKWIYNQNSHQIVHVVSKKCIDYRYNPESLEINIQKCSRKLSQKWIL 1865
            +G+   +++    ++    +G+N L S+++S+HR+IKD R   C+   Y   LP ASI+I F+NE W+ LLRT+HS+L R+P + + EIILVDD S    L  KL++Y+S    K+RI+R  KREGLIR R++GA  A G VL+F+DSHCEV INWL PLLQ I D  K ++CP IDVIS + F         RG F+W   +   P        PE   KP  +P MAGGLFA+ + +F +LG YD G+D+WG E  E+SF++WMCGG +  +PCSRVGH++R+F P+     G+ ++RN  R+AEVW+D +K+Y YQ    +      GD++++ KLRK+L C SF+W++K I  +L           YPI ++P+ +  +GK+   I     FD  + L +PG P        +   E   +  W +    E+K +   +CL+    +    L +  CH  GG Q+W +      + H  +  C+    +       +Q C   + Q+W  
Sbjct:    2 LGIVKNSDDIRTREEGYSAHGFNLLISNRLSLHRTIKDTRHELCRGKTYPKNLPVASIVICFYNEAWTILLRTIHSVLDRTPHQFLHEIILVDDFSNMLELKSKLDRYLST-MPKIRIVRNNKREGLIRGRIIGAEAATGQVLVFLDSHCEVNINWLQPLLQHIHDDQKAVACPVIDVISSDTFEYS-SSPMVRGGFNWGLHFTWEPIPPSLLVKPEDYVKPIRSPTMAGGLFAVDREYFTQLGKYDSGMDIWGAENLEISFRIWMCGGSLDILPCSRVGHLFRRFRPYGSDSKGDTMSRNSMRLAEVWLDGYKKYFYQIRHDLEGK-KFGDISQRIKLRKSLQCKSFEWYLKNIYPELKPPGQPGGGAFYPIDRRPQVVIWKGKVIC-IQLQTSFDDGYCLDSPGHPSEKKASAVIHQCESTKSRFWSLNEDGELKIESL-LCLEASGYQSKLGLRLMKCHAQGGGQQWKFLNKKSVLYHPATGLCLGVNESRTYSTPGMQICDYSIHQQWTF 510          

Query:  369 GPGEQGIGVYLTANENEKAKQLMETNGYNALASDKISVHRSIKDLRINKCKWLK--YDNFLPPASIIIPFHNEHWSTLLRTVHSILHRSPDKLVKEIILVDDNSTKEFLGEKLEQYVSEHFTKVRILRTGKREGLIRARLLGANEANGTVLIFIDSHCEVGINWLPPLLQPIRDHYKTISCPFIDVISYNDFSLRPQDE-GGRGAFDWN--FDYKRLPRLSKDNAHPEKPFY-NPIMAGGLFAISKLWFNELGGYDYGLDVWGGEQYELSFKVWMCGGKMVDVPCSRVGHVYRKF-NPFAVV-GLGNYLARNHKRIAEVWMDDWKQYIYQKHQKVYSSLDPGDLTEQKKLRKALNCTSFDWFMKQIAYDLLEKYPIQKQPENLSQGKIKSEINPHLCFDFNLGNPG-DPFRISNCTDVSNEQNLAFTWEMEIKPQKRDICLDYPR--KGEELTMFSCHGMGGNQKWIYNQNSHQIVHVVSKKCIDYRYNPESLEINIQKCSRKLSQKW 1859
            G G+ G    L     E A    + + +N + SD+IS+ R +KD+R  KCK     Y   LP  S+II FHNE  S LLRTVHS+L+ SP +L+ +IILVDD S  + L + L  ++S    KV+++R   R+GL+ ARL GA EA G VL F+DSHCE    WL PLL  I +  + + CP I+VI+ +DF  +  D    RG F W+  F +K +P   K     E  +  +P MAGGLFAI K +F +LG YD  +++WGGE  E+SF++WMCGG++  VPCSRVGHV+RK+ +P+    G    LARN  R+AEVWMD++K + Y+K  +   ++D GD++++  LRK L C SF W++  I  D+  K P +     L   +I+++    LC D  LG        +  C  +   Q    T   EI     D CLD P    G  + M +CHG+ GNQ+W +N+    IVHV ++ C+D   + + + +N   C    +Q+W
Sbjct:    1 GLGDLGEAATLPTRFKEHAAHAFDNHSFNVMLSDRISLDRRLKDVRGPKCKRKHKLYPRALPTTSVIICFHNEALSVLLRTVHSVLNESPPRLIADIILVDDYSEYDDLKQPLIDHIS-MLNKVKLIRMPSRQGLVPARLRGAEEARGEVLTFLDSHCEATPGWLEPLLVRIAEDRRNVVCPVIEVINADDFRYQASDVIHERGGFTWDLFFTWKAIPEAEKKRRKDETDYIRSPTMAGGLFAIHKKYFYDLGSYDSKMEIWGGENLEMSFRIWMCGGQLEIVPCSRVGHVFRKYTSPYKFPKGTTTTLARNFNRLAEVWMDEYKDHYYRKKTEEERNVDIGDISDRVALRKRLGCKSFKWYLDNIYPDMTNKLPPKSY---LYSHQIRNK-ESSLCLD-TLGEKNIKRVGLYTCHGMGGNQFFTLTKSNEILFND-DKCLDSPNGDPGSYVEMITCHGLKGNQEWKHNKRMGTIVHVWTENCLDISQDGQFIIVN--PCDGSSTQRW 499          

Query:  375 GEQGIGVYLTANENEK-AKQLMETNGYNALASDKISVHRSIKDLRINKCKWLKYDNF---LPPASIIIPFHNEHWSTLLRTVHSILHRSPDKLVKEIILVDDNSTKEFLGEKLEQYVSEHFTKVRILRTGKREGLIRARLLGANEANGTVLIFIDSHCEVGINWLPPLLQPIRDHYKTISCPFIDVISYNDFSLR-PQDEGGRGAFDWN--FDYKRLP----RLSKDNAHPEKPFYNPIMAGGLFAISKLWFNELGGYDYGLDVWGGEQYELSFKVWMCGGKMVDVPCSRVGHVYRKF-NPFAVV-GLGNYLARNHKRIAEVWMDDWKQYIYQKHQKVYSSLDPGDLTEQKKLRKALNCTSFDWFMKQIAYDLLEKYPIQKQPE--NLSQGKIKSEINPHLCFDFNLGNPGDPFRISNCTDVSNEQNLAFTWEMEIKPQKRDICLDYPRK--GEELTMFSCHGMGGNQKWIYNQNSHQIVHVVSKKCIDYRYNPESLEINIQKCSRKLSQKWILEN 1871
            G  G   +L + EN+K A++    + +N L SDKIS+ R++ D+R  +CK  K++ +   LP  S+II FH E  S LLRTVHS+++R+P +L+ E+I+VDD S    LG+ L+ +V++ FTKV++LR  KREGL+RARL GAN A G VL F+DSHCE    W  PLL  I    + + CP I+VI+ + F+ +   +   RG F W+  F +K +P    +L  D++    P   P MAGGLF+I + +F ++G YD  +D+WGGE  ELSF+VWMCGG++  V CSRVGHV+RK+ +P+    G+   L +N  R+AEVWMD++K   Y K  +  +S D GD++++ +LRK L C SF W++  I       YP  + PE    ++G++++  + + C D     P    R+   T      N    +       + + C D  +   G  + +  CHGM GNQ+W +++    ++H  +++C+D R +P      +  C  + SQ+W+  +
Sbjct:    8 GGGGKPAFLESEENKKLAEKYFANHSFNWLLSDKISLDRTLDDVRSERCK-AKHNTYPAKLPTTSVIICFHKERLSVLLRTVHSVINRTPPELLAEVIVVDDFSQDAKLGKPLDDHVAQ-FTKVKVLRMKKREGLVRARLQGANTAKGDVLTFLDSHCEATPGWAEPLLARIAADRRNVVCPAIEVINADTFAYQGSTNADQRGGFSWDLFFKWKGIPPEEQKLRNDDS---DPIRTPTMAGGLFSIHRQYFFDIGSYDEEMDIWGGENLELSFRVWMCGGRLEIVTCSRVGHVFRKYTSPYKFPDGVERTLTKNFNRLAEVWMDEYKDLYYNKKPQAKNS-DYGDISKRLELRKRLKCKSFKWYINNI-------YPDVQMPELDPPARGEVRNP-SSNQCLDSLGAKPEHNARVGIYTCHGQGGNQVSKYMPRELIFEEENCFDVSKTHPGAPVELMKCHGMRGNQEWKHDREKGTLMHFTTQQCLD-RGSPSDQYAVMNPCDGRESQRWVFSH 508          

Query:  408 NENEKAKQLMETNGYNALASDKISVHRSIKDLRINKCKWLKYDNFLPPASIIIPFHNEHWSTLLRTVHSILHRSPDKLVKEIILVDDNS---TKEFLGEKLEQYVSEHFTKVRILRTGKREGLIRARLLGANEANGTVLIFIDSHCEVGINWLPPLLQPIRDHYKTISCPFIDVISYNDFS-LRPQDEGGRGAFDW--NFDYKRLPRLSKDNAHPEK-PFYNPIMAGGLFAISKLWFNELGGYDYGLDVWGGEQYELSFKVWMCGGKMVDVPCSRVGHVYRKFNPFAVVGLGNYLARNHKRIAEVWMDDWKQYIYQKHQKVYSSLDPGDLTEQKKLRKALNCTSFDWFMKQIAYDLL--EKYPIQKQPENLSQGKIKSEINPHLCFDFNLGNPGDPFRISNCTDVSNEQNLAFTWEMEIKPQKRDICLDYPRK---GEELTMFSCHGMGGNQ 1727
            +E E  K+      +N LAS K+++ RSI D R   C  L Y   LP AS+II FHNE WSTLLRTVHS+L RSP  L++EI+LVDD+S   T   LG KLE Y+S+ FTKV+++R  KREGLIRARL+GA +A G VL+F+DSHCE  + WL PLL  I ++   +  P I+VI    F          RG F+W   F ++ +P   +     +  P  +P MAGGLFAI K +F E+G YD  +  WGGE  E+SF++WMCGG +  +PCS+VGHV+R+  P+  +G G  + RN+ R+AEVWMDD+K+  Y    ++    D GD++ +K LR+ L C SF W++  +  +L   + YPI        +G+I+           NLG                                 + CLD   K   G E  M+ CHGMG NQ
Sbjct:    1 SEKEIEKERFRLYQFNELASSKVALDRSIPDNRPQSCLSLSYPTKLPTASVIIIFHNEAWSTLLRTVHSVLARSPPYLLREIVLVDDHSRLDTYGHLGSKLESYISQ-FTKVQLIRAPKREGLIRARLIGAKQAKGEVLVFLDSHCEANLGWLEPLLARIGENRSIVVTPDIEVIDLRTFGYTHEHGANNRGIFNWELTFKWRGIPEYERRRRKSDSDPIRSPTMAGGLFAIDKSYFYEIGSYDTEMSFWGGENVEISFRIWMCGGSLEIIPCSKVGHVFRESQPYK-IGEGA-IDRNNMRLAEVWMDDYKKIFYAMRPQLKGK-DYGDVSGRKALRERLMCKSFKWYLDNVISELAIPDLYPI-------GRGEIR-----------NLGT--------------------------------NTCLDTLAKNEAGGEPGMYMCHGMGNNQ 398          

Query:  252 NILSDWKETSDEINEVSSDSQIKIDWANHDTIDEENARVGPGEQGIGVYLTANENEKAKQLMETNGYNALASDKISVHRSIKDLRINKCKWLKYDNFLPPASIIIPFHNEHWSTLLRTVHSILHRSPDKLVKEIILVDDNSTKEFLGEKLEQYVSEHFTKVRILRTGKREGLIRARLLGANEANGTVLIFIDSHCEVGINWLPPLLQPIRDHYKTISCPFIDVISYNDFSLRPQ-DEGGRGAFDWNFDYKRLP---RLSKDNAHPEKPFYNPIMAGGLFAISKLWFNELGGYDYGLDVWGGEQYELSFKVWMCGGKMVDVPCSRVGHVYRKFNPFAVVGLGNYLARNHKRIAEVWMDDWKQYIYQKHQKVYSSLDPGDLTEQKKLRKALNCTSFDWFMKQIAYDLLEKYPIQKQPENLSQGKIKSEINPHLCFDFNLGNPGDPFRISNCT----DV--SNEQNLAFTWEMEIKP----QKRDICLDYPRKGEELTMFSCHGMGGNQKWIYNQNSHQIVHVVSKKCIDYRYNPESLEINIQKCSRKLSQKWILENMNAMI 1886
             + S  +    ++ +V SD   +IDW ++  +  + AR G GEQG    +T  E ++  Q    NG+N   S++IS++RS+ D+R   C+   Y   LP  +IIIPFHNE WS+LLRTVHS+++RSP +LV EIILVDD S KE L   LE+Y+ + F KVRILRT KREGLIR RLLGA  A G V+ F+DSHCE  +NWLPPLL  I  + KTI CP IDVI +++F    Q  +  RGAFDW   YKR+P    +  D+  P +PF +P+MAGGLFA+ + WF ELGGYD GL++WGGEQYE+SFKVWMCGG+M D+PCSRVGH+YRK+ P+ V G G  LA+N KR+AEVWMD++ +Y+YQ+  + Y  L  GD++ QK+LR  LNC +F WFM+++A+DL + YP   +P   + G+I+S +   +C +      G P R+ +C     DV  S+ Q L F W  +I+       R +C D       +T++ CHGM GNQ W Y ++   + H VS  CID   +   + +N    +  LSQ+W+ E  N  +
Sbjct:   47 GVFSTKQGLHQKVAQVGSDGVRRIDWHDYKAMRRDAARAGNGEQGKPFPVT--ETDRVDQAYRENGFNIYVSNRISLNRSLPDIRHENCRQKLYAEKLPNTTIIIPFHNEGWSSLLRTVHSVINRSPPRLVAEIILVDDFSDKEHLKVALEEYM-KRFPKVRILRTKKREGLIRTRLLGAGAAKGEVITFLDSHCEANVNWLPPLLDRIVQNRKTIVCPMIDVIDHDNFGYDTQAGDAMRGAFDWEMYYKRIPIPAEMRTDD--PTEPFESPVMAGGLFAVDRKWFWELGGYDTGLEIWGGEQYEISFKVWMCGGRMEDIPCSRVGHIYRKYVPYKVPG-GISLAKNLKRVAEVWMDEYAEYVYQRRPE-YRHLSAGDMSAQKELRSHLNCKNFRWFMEEVAWDLPKHYP-PVEPPAAAWGEIRS-VGSGMCMEIKHFVSGSPIRLESCVKGRGDVSWSHGQVLTFGWREDIRVGDPMHTRKVCFDAVSHHSPVTLYDCHGMKGNQLWRYRKDK-SLFHPVSNSCIDSSASERRVFMNTCDPT-SLSQQWLFERTNDTV 594          

Query:  288 INEVSSDSQI------KIDWANHDTIDEENARVGPGEQGIGVYLTANENEKAKQLMETNGYNALASDKISVHRSIKDLRINKCKWLKYDNFLPPASIIIPFHNEHWSTLLRTVHSILHRSPDKLVKEIILVDDNSTKEFLGEKLEQYVSEHFTKVRILRTGKREGLIRARLLGANEANGTVLIFIDSHCEVGINWLPPLLQPIRDHYKTISCPFIDVISYNDFSLRPQ-DEGGRGAFDWNFDYKRLP---RLSKDNAHPEKPFYNPIMAGGLFAISKLWFNELGGYDYGLDVWGGEQYELSFKVWMCGGKMVDVPCSRVGHVYRKFNPFAVVGLGNYLARNHKRIAEVWMDDWKQYIYQKHQKVYSSLDPGDLTEQKKLRKALNCTSFDWFMKQIAYDLLEKYPIQKQPENLSQGKIKSEINPHLCFDFNLGNPGDPFRISNC----TDVS--NEQNLAFTWEMEIKP----QKRDICLDYPRKGEELTMFSCHGMGGNQKWIYNQNSHQIVHVVSKKCIDYRYNPESLEINIQKCSRKLSQKWILENMNAMI 1886
            +N +  DS +      K DW +++ I  +  R G GEQG    LT  + ++  Q    NG+N   SD+IS++RS+ D+R   CK   Y   LP  SIIIPFHNE WS+LLRTVHS+L+RSP +L+ EIILVDD S K+ L   LE+Y+     KVRILRT KREGLIR RLLGA  A G V+ F+DSHCE  INWLPPLL  I  + KTI CP IDVI +++F    Q  +  RGAFDW   YKR+P    L K++  P +PF +P+MAGGLFA+ + WF ELGGYD GL++WGGEQYE+SFKVWMCGG+M D+PCSRVGH+YRK+ P+ V G G  LARN KR+AEVWMD++ +Y+YQ+  + Y  L  GD+  QK+LR  LNC SF WFMK++A+DL + YP   +P   + G+++S  +  LC +      G P R+ +C     DVS  + Q   F W  +I+       + +C D       +T++ CHGM GNQ W Y ++   + H VS  C+D   +   + +N+   +   SQ+W+ E  NA +
Sbjct:   54 VNRMGRDSLVGLGGTRKKDWHDYEAIRRDATRSGNGEQGKAFPLT--DADRVDQAYRENGFNIFVSDRISLNRSVPDIRHPNCKQKLYAERLPNTSIIIPFHNEGWSSLLRTVHSVLNRSPPQLIAEIILVDDFSDKDHLKGALEEYMVR-LPKVRILRTKKREGLIRTRLLGAAAAKGEVITFLDSHCEANINWLPPLLDRIALNRKTIVCPMIDVIDHDNFGYETQAGDAMRGAFDWEMYYKRIPIPAELQKND--PSEPFESPVMAGGLFAVDRKWFWELGGYDTGLEIWGGEQYEISFKVWMCGGRMEDIPCSRVGHIYRKYVPYKVPG-GVSLARNLKRVAEVWMDEYAEYVYQRRPE-YRHLSAGDVAAQKELRSTLNCKSFKWFMKEVAWDLPKHYP-PVEPPAAAWGEVRSAAS-GLCLESKHFVSGTPIRLESCVKGRADVSWGHGQVFTFGWREDIRVGDPMHTKKVCFDAVSHHSPVTLYDCHGMRGNQLWRYRKDK-SLYHPVSNSCVDSNASERRVFMNVCNPA-SASQQWLFEKTNATV 595          

Query:  369 GPGEQGIGVYLTANENEKAKQLMETNGYNALASDKISVHRSIKDLRINKCKWLKYDNFLPPASIIIPFHNEHWSTLLRTVHSILHRSPDKLVKEIILVDDNSTKEFLGEKLEQYVSEHFTKVRILRTGKREGLIRARLLGANEANGTVLIFIDSHCEVGINWLPPLLQPIRDHYKTISCPFIDVISYNDFSLRPQDEGGRGAFDW--NFDYKRLPRLSKDNAHPEK--PFYNPIMAGGLFAISKLWFNELGGYDYGLDVWGGEQYELSFKVWMCGGKMVDVPCSRVGHVYRKFNPFAVV-GLGNYLARNHKRIAEVWMDDWKQYIYQKHQKVYSSLDPGDLTEQKKLRKALNCTSFDWFMKQIAYDLLEKYPIQKQPEN-LSQGKIKSEINPHLCFDFNLGNP-GDPFRISNCTDVSNEQNLAFTWEMEIKPQKRDICLDYPRKGEELTMFSCHGMGGNQKWIYNQNSHQIVHVVSKKCIDYRYNPESLEINIQKCSRKLSQKWILENMNAMI 1886
            GPGE G  V +  ++ EK K+L + N +N +ASD I+++RS+ D+R++ CK   Y + LP  SI+I FHNE WSTLLRTVHS++ RSP  L+ EI+LVDD S ++FL +KLE YV      V+ILR  +R GLIRARL GA    G V+ F+D+HCE    WL PLL  I++    + CP IDVIS   F      +   G F+W  NF +  +P+   D    ++  P   P MAGGLF+I K++F E+G YD G+D+WGGE  E+SF++W CGG +  V CS VGHV+RK  P++   G G  + +N++R+AEVWMD++K + Y     V   +D GD++ +K LR+AL C  F W+++ I       YP  + P    S G+I++ +  + C D N+G    +     NC  +   Q  ++T + EI+    D+CLD  R    + M  CH M GNQ + Y+     ++HV S +C+D     + +   ++ C+   SQ+W+L NM   +
Sbjct:   56 GPGEMGKAVNIAKDDQEKMKELFKINQFNLMASDMIALNRSLPDVRLDGCKTKVYADDLPTTSIVIVFHNEAWSTLLRTVHSVISRSPRHLLVEIVLVDDASERDFLKKKLEGYVRTLEVPVKILRMEQRSGLIRARLRGAAATTGQVITFLDAHCECTEGWLEPLLARIKEDRTAVVCPIIDVISDETFEYMAGSDMTYGGFNWKLNFRWYPVPQREMDRRKGDRTLPVRTPTMAGGLFSIDKMYFEEIGSYDPGMDIWGGENLEMSFRIWQCGGSLEIVTCSHVGHVFRKATPYSFPGGTGQVINKNNRRLAEVWMDEFKDFFYIISPGVM-RVDYGDVSSRKALREALKCKPFAWYLENI-------YPDSQIPRRYYSLGEIRN-VETNQCVD-NMGRKENEKVGFFNCHGMGGNQVFSYTADKEIRTD--DLCLDVSRLNGPVVMLKCHHMKGNQMFEYDAERLTLLHVNSNQCLDMPSEEDKMVPTLRDCNGSRSQQWLLRNMTLSV 556          

Query:  369 GPGEQGIGVYLTANENEKAKQLMETNGYNALASDKISVHRSIKDLRINKCKWLKYDNFLPPASIIIPFHNEHWSTLLRTVHSILHRSPDKLVKEIILVDDNSTKEFLGEKLEQYVSEHFTKVRILRTGKREGLIRARLLGANEANGTVLIFIDSHCEVGINWLPPLLQPIRDHYKTISCPFIDVISYNDFSLRPQDEGGRGAFDW--NFDYKRLPRLSKDNAHPEK--PFYNPIMAGGLFAISKLWFNELGGYDYGLDVWGGEQYELSFKVWMCGGKMVDVPCSRVGHVYRKFNPFAVV-GLGNYLARNHKRIAEVWMDDWKQYIYQKHQKVYSSLDPGDLTEQKKLRKALNCTSFDWFMKQIAYDLLEKYPIQKQPEN-LSQGKIKSEINPHLCFDFNLGNP-GDPFRISNCTDVSNEQNLAFTWEMEIKPQKRDICLDYPRKGEELTMFSCHGMGGNQKWIYNQNSHQIVHVVSKKCIDYRYNPESLEINIQKCSRKLSQKWILENMNAMI 1886
            GPGE G  V +  ++ EK K+L + N +N +ASD I+++RS+ D+R++ CK   Y + LP  SI+I FHNE WSTLLRTVHS++ RSP  L+ EI+LVDD S ++FL +KLE YV      V+ILR  +R GLIRARL GA    G V+ F+D+HCE    WL PLL  I++    + CP IDVIS   F      +   G F+W  NF +  +P+   D    ++  P   P MAGGLF+I K++F E+G YD G+D+WGGE  E+SF++W CGG +  V CS VGHV+RK  P++   G G  + +N++R+AEVWMD++K + Y     V   +D GD++ +K LR+AL C  F W+++ I       YP  + P    S G+I++ +  + C D N+G    +     NC  +   Q  ++T + EI+    D+CLD  R    + M  CH M GNQ + Y+     ++HV S +C+D     + +   ++ C+   SQ+W+L NM   +
Sbjct:   56 GPGEMGKAVNIAKDDQEKMKELFKINQFNLMASDMIALNRSLPDVRLDGCKTKVYADDLPTTSIVIVFHNEAWSTLLRTVHSVISRSPRHLLVEIVLVDDASERDFLKKKLEGYVRTLEVPVKILRMEQRSGLIRARLRGAAATTGQVITFLDAHCECTEGWLEPLLARIKEDRTAVVCPIIDVISDETFEYMAGSDMTYGGFNWKLNFRWYPVPQREMDRRKGDRTLPVRTPTMAGGLFSIDKMYFEEIGSYDPGMDIWGGENLEMSFRIWQCGGSLEIVTCSHVGHVFRKATPYSFPGGTGQVINKNNRRLAEVWMDEFKDFFYIISPGVM-RVDYGDVSSRKALREALKCKPFAWYLENI-------YPDSQIPRRYYSLGEIRN-VETNQCVD-NMGRKENEKVGFFNCHGMGGNQVFSYTADKEIRTD--DLCLDVSRLNGPVVMLKCHHMKGNQMFEYDAERLTLLHVNSNQCLDMPSEEDKMVPTLRDCNGSRSQQWLLRNMTLSV 556          

Query:  369 GPGEQGIGVYLTANENEKAKQLMETNGYNALASDKISVHRSIKDLRINKCKWLKYDNFLPPASIIIPFHNEHWSTLLRTVHSILHRSPDKLVKEIILVDDNSTKEFLGEKLEQYVSEHFTKVRILRTGKREGLIRARLLGANEANGTVLIFIDSHCEVGINWLPPLLQPIRDHYKTISCPFIDVISYNDFSLRPQDEGGRGAFDW--NFDYKRLPRLSKDNAHPEK--PFYNPIMAGGLFAISKLWFNELGGYDYGLDVWGGEQYELSFKVWMCGGKMVDVPCSRVGHVYRKFNPFAVV-GLGNYLARNHKRIAEVWMDDWKQYIYQKHQKVYSSLDPGDLTEQKKLRKALNCTSFDWFMKQIAYDLLEKYPIQKQPEN-LSQGKIKSEINPHLCFDFNLGNP-GDPFRISNCTDVSNEQNLAFTWEMEIKPQKRDICLDYPRKGEELTMFSCHGMGGNQKWIYNQNSHQIVHVVSKKCIDYRYNPESLEINIQKCSRKLSQKWILENMNAMI 1886
            GPGE G  V +  ++ EK K+L + N +N +ASD I+++RS+ D+R++ CK   Y + LP  SI+I FHNE WSTLLRTVHS++ RSP  L+ EI+LVDD S ++FL +KLE YV      V+ILR  +R GLIRARL GA    G V+ F+D+HCE    WL PLL  I++    + CP IDVIS   F      +   G F+W  NF +  +P+   D    ++  P   P MAGGLF+I K++F E+G YD G+D+WGGE  E+SF++W CGG +  V CS VGHV+RK  P++   G G  + +N++R+AEVWMD++K + Y     V   +D GD++ +K LR+AL C  F W+++ I       YP  + P    S G+I++ +  + C D N+G    +     NC  +   Q  ++T + EI+    D+CLD  R    + M  CH M GNQ + Y+     ++HV S +C+D     + +   ++ C+   SQ+W+L NM   +
Sbjct:   56 GPGEMGKAVNIAKDDQEKMKELFKINQFNLMASDMIALNRSLPDVRLDGCKTKVYADDLPTTSIVIVFHNEAWSTLLRTVHSVISRSPRHLLVEIVLVDDASERDFLKKKLEGYVRTLEVPVKILRMEQRSGLIRARLRGAAATTGQVITFLDAHCECTEGWLEPLLARIKEDRTAVVCPIIDVISDETFEYMAGSDMTYGGFNWKLNFRWYPVPQREMDRRKGDRTLPVRTPTMAGGLFSIDKMYFEEIGSYDPGMDIWGGENLEMSFRIWQCGGSLEIVTCSHVGHVFRKATPYSFPGGTGQVINKNNRRLAEVWMDEFKDFFYIISPGVM-RVDYGDVSSRKALREALKCKPFAWYLENI-------YPDSQIPRRYYSLGEIRN-VETNQCVD-NMGRKENEKVGFFNCHGMGGNQVFSYTADKEIRTD--DLCLDVSRLNGPVVMLKCHHMKGNQMFEYDAERLTLLHVNSNQCLDMPSEEDKMVPTLRDCNGSRSQQWLLRNMTLSV 556          

Query:  135 MGFISGSVGIRSFSNKMXXXXXXXXXXXXXXXXXXXXXQNILSDWKETSDEINEVSSDSQIKIDWANHDTIDEENARVGPGEQGIGVYLTANENEKAKQLMETNGYNALASDKISVHRSIKDLRINKCKWLKYDNFLPPASIIIPFHNEHWSTLLRTVHSILHRSPDKLVKEIILVDDNSTKEFLGEKLEQYVSEHFTKVRILRTGKREGLIRARLLGANEANGTVLIFIDSHCEVGINWLPPLLQPIRDHYKTISCPFIDVISYNDFSLRPQDEGGRGAFDWNFDYKRLPRLSKDNAHPEKPFYNPIMAGGLFAISKLWFNELGGYDYGLDVWGGEQYELSFKVWMCGGKMVDVPCSRVGHVYRKFNPFAVVGLGNYLARNHKRIAEVWMDDWKQYIYQKHQKVYSSLDPGDLTEQKKLRKALNCTSFDWFMKQIAYDLLEKYPIQKQPENLSQGKIKSEINPHLCFDFNLGNPGDPFRISNCTDVSNEQNLAFTWEMEIKPQKRDICLDYPRKGEELTMFSCHGMGGNQKWIYNQNSHQIVHVVSKKCIDYRYNPESLEINIQKCSRKLSQKWILENMNAMIANHLWKEIKL 1916
            MGFISGSVGIRSFSNKMLRIKLKKILLFFIVLLGIFLIQNILSDWKETSDEINEVSSDSQIKIDWANHDTIDEENARVGPGEQGIGVYLTANENEKAKQLMETNGYNALASDKISVHRSIKDLRINKCKWLKYDNFLPPASIIIPFHNEHWSTLLRTVHSILHRSPDKLVKEIILVDDNSTKEFLGEKLEQYVSEHFTKVRILRTGKREGLIRARLLGANEANGTVLIFIDSHCEVGINWLPPLLQPIRDHYKTISCPFIDVISYNDFSLRPQDEGGRGAFDWNFDYKRLPRLSKDNAHPEKPFYNPIMAGGLFAISKLWFNELGGYDYGLDVWGGEQYELSFKVWMCGGKMVDVPCSRVGHVYRKFNPFAVVGLGNYLARNHKRIAEVWMDDWKQYIYQKHQKVYSSLDPGDLTEQKKLRKALNCTSFDWFMKQIAYDLLEKYPIQKQPENLSQGKIKSEINPHLCFDFNLGNPGDPFRISNCTDVSNEQNLAFTWEMEIKPQKRDICLDYPRKGEELTMFSCHGMGGNQKWIYNQNSHQIVHVVSKKCIDYRYNPESLEINIQKCSRK SQKWILENMNAMIANHLWKEIKL
Sbjct:    1 MGFISGSVGIRSFSNKMLRIKLKKILLFFIVLLGIFLIQNILSDWKETSDEINEVSSDSQIKIDWANHDTIDEENARVGPGEQGIGVYLTANENEKAKQLMETNGYNALASDKISVHRSIKDLRINKCKWLKYDNFLPPASIIIPFHNEHWSTLLRTVHSILHRSPDKLVKEIILVDDNSTKEFLGEKLEQYVSEHFTKVRILRTGKREGLIRARLLGANEANGTVLIFIDSHCEVGINWLPPLLQPIRDHYKTISCPFIDVISYNDFSLRPQDEGGRGAFDWNFDYKRLPRLSKDNAHPEKPFYNPIMAGGLFAISKLWFNELGGYDYGLDVWGGEQYELSFKVWMCGGKMVDVPCSRVGHVYRKFNPFAVVGLGNYLARNHKRIAEVWMDDWKQYIYQKHQKVYSSLDPGDLTEQKKLRKALNCTSFDWFMKQIAYDLLEKYPIQKQPENLSQGKIKSEINPHLCFDFNLGNPGDPFRISNCTDVSNEQNLAFTWEMEIKPQKRDICLDYPRKGEELTMFSCHGMGGNQKWIYNQNSHQIVHVVSKKCIDYRYNPESLEINIQKCSRKSSQKWILENMNAMIANHLWKEIKL 594          

Query:  321 IDWANHDTIDEENARVGPGEQGIGVYLTANENEKAKQLMETNGYNALASDKISVHRSIKDLRINKCKWLKYDNFLPPASIIIPFHNEHWSTLLRTVHSILHRSPDKLVKEIILVDDNSTKEFLGEKLEQYVSEHFTKVRILRTGKREGLIRARLLGANEANGTVLIFIDSHCEVGINWLPPLLQPIRDHYKTISCPFIDVISYNDFSLRPQDEGGRGAFDWNFDYKRLPRLSKDNAHPEKPFYNPIMAGGLFAISKLWFNELGGYDYGLDVWGGEQYELSFKVWMCGGKMVDVPCSRVGHVYRKFNPFAVVGLGNYLARNHKRIAEVWMDDWKQYIYQKHQKVYSSLDPGDLTEQKKLRKALNCTSFDWFMKQIAYDLLEKYP-IQKQPENLSQGKIKSEINPHLCFDFNLGNPGDPFRISNCTDVSN----EQNLAFTWEMEIKPQKRDICLDYPRK--GEELTMFSCHGMGGNQKWIYNQNSHQIVHVVSKKCIDYRYNPESLEINIQKCSRKLS-QKWILENMN 1877
            +DW N+  I+EE  R GPGEQG GV +   E E+ +++ + NGY+  ASDKIS+ RS++D+R   CK LKY   LP  S+IIPFH EHWS L+RTV S++ R+P  L+KE+ILVDD S K FL + LE ++ EH+   ++LRT  R+GLIR R+LGA EA G VLIF+DSH E  +NWLPPLL+PI  +YKT++CPFIDVI+Y+ F    QDEG RG FDWNFDYKR+PR   D +HP  PF +P+MAGGLFAIS+ WF ELGGYD GLD+WGGEQYE+SFK+W CGGKM+DVPCSR+GHVYRK++PF     GN+++RN KR+AEVWMD++K+Y+Y +   + +  DP +LT Q  +R+ L+C +F WFMK++A+DL+  YP I+  P    + K+ +  N  +C DF   + G    +S C  V++    EQN   +W+ EIKP+ RD+C+D      G  + +F CHG  GNQ + Y   S QI+ V S  C++   +P S  I +Q C+  ++ QKWI  ++N
Sbjct:   66 VDWHNYTQIEEELKRRGPGEQGSGVRIPKAEEEEQQRIYKENGYDGYASDKISIQRSLRDIRHPACKTLKYLKSLPSVSVIIPFHQEHWSPLIRTVDSVIRRAPLGLIKEVILVDDASRKPFLQKTLEIFLKEHYPIAKVLRTNGRQGLIRTRVLGAKEAIGDVLIFLDSHSEANVNWLPPLLEPIAKNYKTVTCPFIDVINYDTFEYLSQDEGARGIFDWNFDYKRIPRFKSDESHPADPFESPVMAGGLFAISRKWFWELGGYDEGLDIWGGEQYEISFKLWQCGGKMLDVPCSRIGHVYRKYSPFPNNAKGNFISRNFKRVAEVWMDEFKEYLYLRRPTIRNE-DPLNLTNQFAIREKLHCKNFSWFMKEVAFDLVNNYPLIEPNPVCSGEIKLSNPNNVSVCIDFKFRDSGYVVGLSPCLSVNHKEGGEQNFILSWKGEIKPKDRDMCMDSSDHIPGGSVLLFKCHGGRGNQFFKYKLESQQILFVNSGFCLE--GDPASKHIALQTCNETITDQKWIWTSVN 589          

Query:  303 SDSQIKIDWANHDTIDEENARVGPGEQGIGVYLTANENEKAKQLMETNGYNALASDKISVHRSIKDLRINKCKWLKYDNFLPPASIIIPFHNEHWSTLLRTVHSILHRSPDKLVKEIILVDDNSTKEFLGEKLEQYVSEHFTK-VRILRTGKREGLIRARLLGANEANGTVLIFIDSHCEVGINWLPPLLQPIRDHYKTISCPFIDVISYNDFSLRPQDEGGRGAFDWNFDYKRLPRLSKDNAHPEKPFYNPIMAGGLFAISKLWFNELGGYDYGLDVWGGEQYELSFKVWMCGGKMVDVPCSRVGHVYRKFNPF-AVVGLGNYLARNHKRIAEVWMDDWKQYIYQKHQKVYSSLDPGDLTEQKKLRKALNCTSFDWFMKQIAYDLLEKYPIQKQPENLSQGKIKSEI----NPHLCFDFNLGNPGDPFRISNC----TDVSNEQNLAFTWEMEIKPQKRDICLDYPRK--GEELTMFSCHGMGGNQKWIYNQNSHQIVHVVSKKCIDYRYNPESLEINIQKCSRKLSQKWILENM 1874
            +D + KIDW N+  I EE+ R G GE G  V L ++EN   + + + NG+N LASDK++++RS+KD+R   CK + Y   LP  SIIIPF+ EHWSTLLRT  S L R+P  LVKEIILVDD STKEFL +KL+QY+  +F   VR+LR  KREGLIR RL GA  A G VLIF+DSHCE  INWLPPLL PI   Y+T++CPFIDV+ ++ F  R QDEG RGAFDW F YKRLP L +D  +P +PF +P+MAGGLFAIS+ WF ELGGYD GLD+WGGEQYELSFK+W CGG+M+D PCSR+ HVYRK+ PF +VV +GN++ARN+KR+AEVWMD++++Y+Y++ Q  +   + GDLT Q  +R+ L C SF WFM +IA+DL + YP   +P N + G+++S++       LC D          R++ C    + ++ EQ    TW  +++ + RD CLD P+      + ++SCHG  GNQ W Y  +S Q+ HVV++KC+      +S+ ++   C+   +QKW LEN+
Sbjct:   52 TDPKKKIDWHNYKQILEESQREGVGEHGSAVILDSSENNLKESIFKVNGFNGLASDKMALNRSVKDIRHPDCKKMLYQKSLPSVSIIIPFYEEHWSTLLRTFISALIRAPKGLVKEIILVDDCSTKEFLKDKLDQYIENNFKGIVRVLRQDKREGLIRTRLKGAKNATGDVLIFLDSHCEANINWLPPLLDPIAQDYRTVTCPFIDVLDHDTFEYRAQDEGARGAFDWEFYYKRLPLLPEDLKYPARPFKSPVMAGGLFAISRKWFWELGGYDPGLDIWGGEQYELSFKIWQCGGQMLDTPCSRIAHVYRKYAPFPSVVNIGNFIARNYKRVAEVWMDEYRKYLYRR-QPSWERENAGDLTAQFAIRERLKCKSFKWFMTEIAFDLEKHYP-SVEPPNSADGEVRSKVFNSDGNSLCLDAKFAKSESQIRLAPCVKDNSRLTGEQKFLLTWHEDLRLKSRDECLDVPQNMFKSPVILYSCHGQKGNQLWKYKLDSKQLYHVVTQKCLTADGPTQSVYMDT--CTSSSNQKWYLENV 583          

Query:  276 TSDEINEVSSDSQIKIDWANHDTIDEENARVGPGEQGIGVYLTANENEKAKQLMETNGYN-ALASDKISVHRSIKDLRINKCKWLKYDNFLPPASIIIPFHNEHWSTLLRTVHSILHRSPDKLVKEIILVDDNSTKEFLGEKLEQYVSEHFTKVRILRTGKREGLIRARLLGANEANGTVLIFIDSHCEVGINWLPPLLQPIRDHYKTISCPFIDVISYNDFSLRPQDEGGRGAFDWNFDYKRLPRLSKDNAHPEKPFYNPIMAGGLFAISKLWFNELGGYDYGLDVWGGEQYELSFKVWMCGGKMVDVPCSRVGHVYRKFNPFAVVGLGNYLARNHKRIAEVWMDDWKQYIYQKHQKVYSSLDPGDLTEQKKLRKALNCTSFDWFMKQIAYDLLEKYPIQKQPENLSQGKIKSEINPHLCFDFNLGNPGDPFRISNCTDV-----SNEQNLAFTWEMEIKPQKRDICLDYPRKGEELTMFSCHGMGGNQKWIYNQNSHQIVHVVSKKCIDYRYNPESLEINIQKCSRKLS-QKWILENMNAMI 1886
            +S +I    S ++ K++  NH   D+EN R             +N N   K++  T  +N +   +K+S++R+I +L+I KCKWL+++  LP  SIII F++  W TL++T   +L RSP +L+KEI+++DDN+    +  K+  YVS+HFT VR++   KREGLI+ARLLGA  A G VL+F+DSHC VG+ WLPPLL+PI+++YKT++CPFID I+  D SL  QDEG RGAFDWNF+Y RLPRL  +   PE PF NPIM G +FAI++ WF ELGGYD GL++WGGEQ+ELSFK+WMCGG+MV+VPCSR+  +++    F  +     + +N+KRIAE+WMD+WK++IYQ+H + YSS D GD+++QKKL++ LNC SFDWFM+ +AYD+L  YP     E L+   I  E +  +C D      GD   I  C  +     + EQ  +FT + EI+P +R++C DY    E L +  C  M  NQKW YN  SHQI ++ S+KCI  + N +SL + +  CS   + QKWI++  +AMI
Sbjct:   23 SSFQIQSALSKNEHKLE--NHGLSDQENIRN-----------LSNINLMMKRMHSTRRFNNSFEEEKVSLYRTINELKITKCKWLRHNKTLPSVSIIITFYDSDWETLMQTTRMLLLRSPRRLIKEILIIDDNADNNDMRSKMNAYVSKHFTNVRVVHKTKREGLIKARLLGAKLAKGKVLVFMDSHCTVGVKWLPPLLEPIKENYKTVTCPFID-INDTDTSLYSQDEGARGAFDWNFNYTRLPRLHNNKTDPEDPFDNPIMQGRIFAITRNWFWELGGYDEGLEIWGGEQFELSFKIWMCGGRMVNVPCSRIRCIFKDIYSFDFIHDDIKIRKNYKRIAEIWMDNWKKFIYQRHLEEYSSFDCGDISKQKKLQQKLNCKSFDWFMENVAYDILYLYPPITVSEKLN-CSITLESDDSICVDSKYRKQGDRVGIDQCNQIGRSEKNKEQRFSFTSDFEIRPGQRNLCFDYRNSSETLMLSQCDLMNPNQKWEYNSTSHQITNIPSQKCI--KVNSKSLLLLVNNCSLSSTMQKWIIQ--DAMI 547          

Query:  276 TSDEINEVSSDSQIKIDWANHDTIDEENARVGPGEQGIGVYLTANENEKAKQLMETNGYN-ALASDKISVHRSIKDLRINKCKWLKYDNFLPPASIIIPFHNEHWSTLLRTVHSILHRSPDKLVKEIILVDDNSTKEFLGEKLEQYVSEHFTKVRILRTGKREGLIRARLLGANEANGTVLIFIDSHCEVGINWLPPLLQPIRDHYKTISCPFIDVISYNDFSLRPQDEGGRGAFDWNFDYKRLPRLSKDNAHPEKPFYNPIMAGGLFAISKLWFNELGGYDYGLDVWGGEQYELSFKVWMCGGKMVDVPCSRVGHVYRKFNPFAVVGLGNYLARNHKRIAEVWMDDWKQYIYQKHQKVYSSLDPGDLTEQKKLRKALNCTSFDWFMKQIAYDLLEKYPIQKQPENLSQGKIKSEINPHLCFDFNLGNPGDPFRISNCTDV-----SNEQNLAFTWEMEIKPQKRDICLDYPRKGEELTMFSCHGMGGNQKWIYNQNSHQIVHVVSKKCIDYRYNPESLEINIQKCSRKLS-QKWILENMNAMI 1886
            +S +I    S ++ K++  NH   D+EN R             +N N   K++  T  +N +   +K+S++R+I +L+I KCKWL+++  LP  SIII F++  W TL++T   +L RSP +L+KEI+++DDN+    +  K+  YVS+HFT VR++   KREGLI+ARLLGA  A G VL+F+DSHC VG+ WLPPLL+PI+++YKT                   DEG RGAFDWNF+Y RLPRL  +   PE PF NPIM G +FAI++ WF ELGGYD GL++WGGEQ+ELSFK+WMCGG+MV+VPCSR+  +++    F  +     + +N+KRIAE+WMD+WK++IYQ+H + YSS D GD+++QKKL++ LNC SFDWFM+ +AYD+L  YP     E L+   I  E +  +C D      GD   I  C  +     + EQ  +FT + EI+P +R++C DY    E L +  C  M  NQKW YN  SHQI ++ S+KCI  + N +SL + +  CS   + QKWI++  +AMI
Sbjct:   23 SSFQIQSALSKNEHKLE--NHGLSDQENIRN-----------LSNINLMMKRMHSTRRFNNSFEEEKVSLYRTINELKITKCKWLRHNKTLPSVSIIITFYDSDWETLMQTTRMLLLRSPRRLIKEILIIDDNADNNDMRSKMNAYVSKHFTNVRVVHKTKREGLIKARLLGAKLAKGKVLVFMDSHCTVGVKWLPPLLEPIKENYKT-------------------DEGARGAFDWNFNYTRLPRLHNNKTDPEDPFDNPIMQGRIFAITRNWFWELGGYDEGLEIWGGEQFELSFKIWMCGGRMVNVPCSRIRCIFKDIYSFDFIHDDIKIRKNYKRIAEIWMDNWKKFIYQRHLEEYSSFDCGDISKQKKLQQKLNCKSFDWFMENVAYDILYLYPPITVSEKLN-CSITLESDDSICVDSKYRKQGDRVGIDQCNQIGRSEKNKEQRFSFTSDFEIRPGQRNLCFDYRNSSETLMLSQCDLMNPNQKWEYNSTSHQITNIPSQKCI--KVNSKSLLLLVNNCSLSSTMQKWIIQ--DAMI 529