WD repeat-containing protein 49

Overview
NameWD repeat-containing protein 49
Smed IDSMED30009463
Length (bp)3966
Neoblast Clusters

Zeng et. al., 2018




 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020




SMED30009463

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 10

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
head regionSMED30009463h1SMcG0015878 SmedASXL_015119SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016
whole organism asexual adult RNA-sequencing evidence
pharynxSMED30009463h1SMcG0015878 dd_Smed_v4_13248_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
protonephridiaSMED30009463h1SMcG0015878 dd_Smed_v4_13248_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
nervous systemSMED30009463h1SMcG0015878 dd_Smed_v4_13248_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30009463h1SMcG0015878 dd_Smed_v4_13248_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30009463h1SMcG0015878 dd_Smed_v4_13248_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neuronSMED30009463h1SMcG0015878 dd_Smed_v4_13248_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
whole organism asexual adult colorimetric in situ hybridization evidence
neoblastSMED30009463h1SMcG0015878 dd_Smed_v4_13248_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
head regionSMED30009463h1SMcG0015878 dd_Smed_v6_13248_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017
whole organism asexual adult RNA-sequencing evidence
epidermisSMED30009463h1SMcG0015878 dd_Smed_v4_13248_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017
whole organism asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
BLAST of WD repeat-containing protein 49 vs. Ensembl Human
Match: WDR49 (WD repeat domain 49 [Source:HGNC Symbol;Acc:HGNC:26587])

HSP 1 Score: 553.518 bits (1425), Expect = 8.736e-177
Identity = 283/652 (43.40%), Postives = 411/652 (63.04%), Query Frame = 3
Query:  132 LELKLNIKDLETLQEAFFMDGSHNRSQHFNGEEFVEALSLVLCKGTREEYSDLFDKIDITREGYVDWEKFASHMLLEFYEKDDRTKSSSLPQWKELKTLSGPHKDVIQRIVLVRNLNRYLTISKEGNVGLWGSDCKLQKVAKTHTESCRSRDLWVTDFAFLGNVNKVAVSFTSKEISFYDMNVKLEFNCQVKLENLFRIPICMDYWHHPDNNGEAIMAWGDTGGYINVILWSNISSSLFERVSSKASDKDENTXXXXXXXXXXXXXKTCTYFSHKAHQ-DWVRKVSYIPNLECFVSCATNWNTSMVICWMEKYNPSNSTSSEMAGIPESRGFSRTSCFTVHQGINSFAYNENLNLIATAGVNFQVCLWNPYVISKPNGLLRGHMASVTDVQFNKARGHLISFSKDKILRIWDVQLQVCIQRYAGVFPKGQEMYSKMFYHEEKLRLFITFNFGLTMLEMKPDVKDKISSHEKPLIGCLYNSLYNQVVTACQGGIIYCWMVDTGQRVKTITEICGPQAELTCITQDSTQTRLYTGATDGNVKIWDFNGHCYNTLIVANGNPVDISQIVILKRCVLVFGFSKSITAFWTSSFKDHKVSPSPWKGVQTHKDDILSGASIPPHAVATGSYDGEIIIWNINSEQASRTMTQRSQDEMK 2084
            LE +L++ D   +Q+AF       +    + E+F + ++ ++  GT+EEY +LFDK+D+ ++G+++W+K  S +LLE YE+D+R K++ +PQWK+L+ L   HKD IQ+++ ++N + YLTISKEG + +WG   KLQ+     +++ + + LWVT    L NVNK+AV+FTSKE+ FYD+  K EF CQ KL+ L   PICMDYW+ P +  E+I+++GD  G +  I ++    SLFER +S   D  E T+ I+  +++ G  K C    HK HQ DWVR+V+Y  +L+  +S  T+   S+V+ W EK                S+     + F + QGI++F Y+  LNLIATAG+N +VCLWNPYV+SKP G+L GH ASV  VQF   R  L SFSKDK+LR+WD+Q Q+ IQR A  FPK Q+      + E   RLFI+FN  L +L MK +   ++ SHEK +   LYNS+  QV+++  G  +  WM+DTGQ++K  T  C   AE++ +  D+ +TRL TG+TDG VKIWDFNG+C++TL V     VDISQI+ILK+ +LV G+ ++IT F   +F    + P  WKG   H DDIL  A +PP  + TGSYDGEI++WN ++E A   +    Q  +K
Sbjct:   38 LENQLSVGDFVKIQKAF-ESPQPRKIICMSREDFTQKMTEIVGWGTKEEYGELFDKVDVAQDGFINWDKLTSFILLELYEQDERAKATVVPQWKDLEFLPVKHKDTIQKVIFLKNSSHYLTISKEGLLAIWGEHLKLQETFPITSDATKLKHLWVTSLVSLENVNKIAVAFTSKEVCFYDLLSKEEFACQYKLQGLKGTPICMDYWYDPLDANESILSFGDITGKVQAIAFTAALISLFERPASACED-GEATMTINWAELLSGCHKCCHILEHKLHQGDWVRQVTYNASLDAIISSTTSNTNSVVMAWREK----------------SKKRLNMTSFNIAQGIHAFDYHSRLNLIATAGINNKVCLWNPYVVSKPVGVLWGHSASVIAVQFFVERKQLFSFSKDKVLRLWDIQHQLSIQRIACSFPKSQDFRCLFHFDEAHGRLFISFNNQLALLAMKSEASKRVKSHEKAVTCVLYNSILKQVISSDTGSTVSFWMIDTGQKIKQFTG-CHGNAEISTMALDANETRLLTGSTDGTVKIWDFNGYCHHTLNVGQDGAVDISQILILKKKILVTGWERAITVFRPQNFNQFFIQPEEWKGGIQHHDDILCAAFLPPQTLVTGSYDGEIVLWNNSTENAHHVLHPDYQRLLK 670          

HSP 2 Score: 197.208 bits (500), Expect = 1.460e-50
Identity = 123/333 (36.94%), Postives = 178/333 (53.45%), Query Frame = 3
Query: 2355 ISRLIYLESRKKIKHGGGANLISCGGNGIVRFWNSAEGWLIGEFVAHENASNIIMNTDVSNQYLVTGDMDGYIRVWDILSYCQTESENQKIMSPPTLISQWQSHSDEISGISFCFKFSRTLIITSSADQSAALWELNGVLIGRFGQEHRWKLGSXXXXXXXXXXXXHEDEVVKQEEDKYKVDPNWYPDPEAIQNP-----SGYRINTWKDTNLGKDYQELRVRKRERIQPSSIPDLPYLYGEKIGRPTFGPFYSLNISSFEEIEDIEQPEFMEYPEKFF-NETEEFLTKTARVPLLNETLKAVFDERSLLPEYILEFEHKFRNRFQRHLSEAK 3335
            + RL +L++RK     GGANL+SCGG+G VRFW+  +  L+ EF+AH    +IIM+TD  N+YL TGD+DG++++W+I  YC   S+N KI   PTLI  +Q H D IS +  C    + LII+SSAD S  +  +    +  FGQ   W + + +  P        E E+ K+     K +    P   ++ N      S Y +   +D NL   Y+E     +E  +P         YGE I + +F  F SLNI + EE+ ++ +P F+  PEK+F  E EE   +    P L +TLKAVFDE++L P+ IL  E K +   Q    E K
Sbjct:  713 VMRLCFLKARKNTAVTGGANLVSCGGSGYVRFWDIYKKQLLAEFLAHSGVGSIIMSTDKMNRYLTTGDLDGWLKIWNIEEYCLNSSKN-KITKAPTLIRSFQPHEDRISSLEMCEPGGQLLIISSSADCSICVTGVCNAPVWIFGQAKHWHIENCLFLPKRDTNLV-ESEIQKEISLFSKEESCLDPTEHSLLNKKNKDDSTYNVRPSEDINLDIKYKERSTCMKETQKP--------YYGEVI-KKSFSTFRSLNIGALEELPEVNKPAFLLDPEKYFRKEPEEERPQILEAPSLFKTLKAVFDEKNLFPKEILHHERKAKQLCQEKSCEVK 1034          
BLAST of WD repeat-containing protein 49 vs. Ensembl Human
Match: WDR49 (WD repeat domain 49 [Source:HGNC Symbol;Acc:HGNC:26587])

HSP 1 Score: 409.068 bits (1050), Expect = 5.331e-126
Identity = 218/497 (43.86%), Postives = 301/497 (60.56%), Query Frame = 3
Query:  630 VAVSFTSKEISFYDMNVKLEFNCQVKLENLFRIPICMDYWHHPDNNGEAIMAWGDTGGYINVILWSNISSSLFERVSSKASDKDENTXXXXXXXXXXXXXKTCTYFSHKAHQ-DWVRKVSYIPNLECFVSCATNWNTSMVICWMEKYNPSNSTSSEMAGIPESRGFSRTSCFTVHQGINSFAYNENLNLIATAGVNFQVCLWNPYVISKPNGLLRGHMASVTDVQFNKARGHLISFSKDKILRIWDVQLQVCIQRYAGVFPKGQEMYSKMFYHEEKLRLFITFNFGLTMLEMKPDVKDKISSHEKPLIGCLYNSLYNQVVTACQGGIIYCWMVDTGQRVKTITEICGPQAELTCITQDSTQTRLYTGATDGNVKIWDFNGHCYNTLIVANGNPVDISQIVILKRCVLVFGF-----------SKSITAFWTSSFKDHKVSPSPWKGVQTHKDDILSGASIPPHAVATGSYDGEIIIWNINSEQASRTMTQRSQDEMK 2084
            +AV+FTSKE+ FYD+  K EF CQ KL+ L   PICMDYW+ P +  E+I+++GD  G +  I ++    SLFER +S   D  E T+ I+  +++ G  K C    HK HQ DWVR+V+Y  +L+  +S  T+   S+V+ W EK                S+     + F + QGI++F Y+  LNLIATAG+N +VCLWNPYV+SKP G+L GH ASV  VQF   R  L SFSKDK+LR+WD+Q Q+ IQR A  FPK Q+      + E   RLFI+FN  L +L MK +   ++ SHEK +   LYNS+  QV+++  G  +  WM+DTGQ++K  T  C   AE++ +  D+ +TRL TG+TDG VKIWDFNG+C++TL V     VDISQI+ILK+ +LV G+            ++IT F   +F    + P  WKG   H DDIL  A +PP  + TGSYDGEI++WN ++E A   +    Q  +K
Sbjct:    1 IAVAFTSKEVCFYDLLSKEEFACQYKLQGLKGTPICMDYWYDPLDANESILSFGDITGKVQAIAFTAALISLFERPASACED-GEATMTINWAELLSGCHKCCHILEHKLHQGDWVRQVTYNASLDAIISSTTSNTNSVVMAWREK----------------SKKRLNMTSFNIAQGIHAFDYHSRLNLIATAGINNKVCLWNPYVVSKPVGVLWGHSASVIAVQFFVERKQLFSFSKDKVLRLWDIQHQLSIQRIACSFPKSQDFRCLFHFDEAHGRLFISFNNQLALLAMKSEASKRVKSHEKAVTCVLYNSILKQVISSDTGSTVSFWMIDTGQKIKQFTG-CHGNAEISTMALDANETRLLTGSTDGTVKIWDFNGYCHHTLNVGQDGAVDISQILILKKKILVTGWERYDYASWKTIGRAITVFRPQNFNQFFIQPEEWKGGIQHHDDILCAAFLPPQTLVTGSYDGEIVLWNNSTENAHHVLHPDYQRLLK 479          

HSP 2 Score: 95.1301 bits (235), Expect = 4.146e-19
Identity = 39/78 (50.00%), Postives = 58/78 (74.36%), Query Frame = 3
Query: 2355 ISRLIYLESRKKIKHGGGANLISCGGNGIVRFWNSAEGWLIGEFVAHENASNIIMNTDVSNQYLVTGDMDGYIRVWDI 2588
            + RL +L++RK     GGANL+SCGG+G VRFW+  +  L+ EF+AH    +IIM+TD  N+YL TGD+DG++++W+I
Sbjct:  522 VMRLCFLKARKNTAVTGGANLVSCGGSGYVRFWDIYKKQLLAEFLAHSGVGSIIMSTDKMNRYLTTGDLDGWLKIWNI 599          

HSP 3 Score: 76.2554 bits (186), Expect = 3.138e-13
Identity = 49/136 (36.03%), Postives = 71/136 (52.21%), Query Frame = 3
Query: 2931 QNPSGYRINTWKDTNLGKDYQELRVRKRERIQPSSIPDLPYLYGEKIGRPTFGPFYSLNISSFEEIEDIEQPEFMEYPEKFF-NETEEFLTKTARVPLLNETLKAVFDERSLLPEYILEFEHKFRNRFQRHLSEAK 3335
            ++ S Y +   +D NL   Y+E     +E  +P         YGE I + +F  F SLNI + EE+ ++ +P F+  PEK+F  E EE   +    P L +TLKAVFDE++L P+ IL  E K +   Q    E K
Sbjct:  618 KDDSTYNVRPSEDINLDIKYKERSTCMKETQKP--------YYGEVI-KKSFSTFRSLNIGALEELPEVNKPAFLLDPEKYFRKEPEEERPQILEAPSLFKTLKAVFDEKNLFPKEILHHERKAKQLCQEKSCEVK 744          
BLAST of WD repeat-containing protein 49 vs. Ensembl Human
Match: WDR49 (WD repeat domain 49 [Source:HGNC Symbol;Acc:HGNC:26587])

HSP 1 Score: 397.127 bits (1019), Expect = 1.614e-124
Identity = 207/484 (42.77%), Postives = 303/484 (62.60%), Query Frame = 3
Query:  132 LELKLNIKDLETLQEAFFMDGSHNRSQHFNGEEFVEALSLVLCKGTREEYSDLFDKIDITREGYVDWEKFASHMLLEFYEKDDRTKSSSLPQWKELKTLSGPHKDVIQRIVLVRNLNRYLTISKEGNVGLWGSDCKLQKVAKTHTESCRSRDLWVTDFAFLGNVNKVAVSFTSKEISFYDMNVKLEFNCQVKLENLFRIPICMDYWHHPDNNGEAIMAWGDTGGYINVILWSNISSSLFERVSSKASDKDENTXXXXXXXXXXXXXKTCTYFSHKAHQ-DWVRKVSYIPNLECFVSCATNWNTSMVICWMEKYNPSNSTSSEMAGIPESRGFSRTSCFTVHQGINSFAYNENLNLIATAGVNFQVCLWNPYVISKPNGLLRGHMASVTDVQFNKARGHLISFSKDKILRIWDVQLQVCIQRYAGVFPKGQEMYSKMFYHEEKLRLFITFNFGLTMLEMKPDVKDKISSHEKPLIGCLYNSLYNQ 1580
            LE +L++ D   +Q+AF       +    + E+F + ++ ++  GT+EEY +LFDK+D+ ++G+++W+K  S +LLE YE+D+R K++ +PQWK+L+ L   HKD IQ+++ ++N + YLTISKEG + +WG   KLQ+     +++ + + LWVT    L NVNK+AV+FTSKE+ FYD+  K EF CQ KL+ L   PICMDYW+ P +  E+I+++GD  G +  I ++    SLFER +S   D  E T+ I+  +++ G  K C    HK HQ DWVR+V+Y  +L+  +S  T+   S+V+ W EK                S+     + F + QGI++F Y+  LNLIATAG+N +VCLWNPYV+SKP G+L GH ASV  VQF   R  L SFSKDK+LR+WD+Q Q+ IQR A  FPK Q+      + E   RLFI+FN  L +L MK +   ++ SHEK +   LYNS+  Q
Sbjct:   38 LENQLSVGDFVKIQKAF-ESPQPRKIICMSREDFTQKMTEIVGWGTKEEYGELFDKVDVAQDGFINWDKLTSFILLELYEQDERAKATVVPQWKDLEFLPVKHKDTIQKVIFLKNSSHYLTISKEGLLAIWGEHLKLQETFPITSDATKLKHLWVTSLVSLENVNKIAVAFTSKEVCFYDLLSKEEFACQYKLQGLKGTPICMDYWYDPLDANESILSFGDITGKVQAIAFTAALISLFERPASACED-GEATMTINWAELLSGCHKCCHILEHKLHQGDWVRQVTYNASLDAIISSTTSNTNSVVMAWREK----------------SKKRLNMTSFNIAQGIHAFDYHSRLNLIATAGINNKVCLWNPYVVSKPVGVLWGHSASVIAVQFFVERKQLFSFSKDKVLRLWDIQHQLSIQRIACSFPKSQDFRCLFHFDEAHGRLFISFNNQLALLAMKSEASKRVKSHEKAVTCVLYNSILKQ 503          
BLAST of WD repeat-containing protein 49 vs. Ensembl Human
Match: WDR49 (WD repeat domain 49 [Source:HGNC Symbol;Acc:HGNC:26587])

HSP 1 Score: 318.546 bits (815), Expect = 1.471e-93
Identity = 157/330 (47.58%), Postives = 213/330 (64.55%), Query Frame = 3
Query: 1095 MAGIPESRGFSRTSCFTVHQGINSFAYNENLNLIATAGVNFQVCLWNPYVISKPNGLLRGHMASVTDVQFNKARGHLISFSKDKILRIWDVQLQVCIQRYAGVFPKGQEMYSKMFYHEEKLRLFITFNFGLTMLEMKPDVKDKISSHEKPLIGCLYNSLYNQVVTACQGGIIYCWMVDTGQRVKTITEICGPQAELTCITQDSTQTRLYTGATDGNVKIWDFNGHCYNTLIVANGNPVDISQIVILKRCVLVFGFSKSITAFWTSSFKDHKVSPSPWKGVQTHKDDILSGASIPPHAVATGSYDGEIIIWNINSEQASRTMTQRSQDEMK 2084
            MA   +S+     + F + QGI++F Y+  LNLIATAG+N +VCLWNPYV+SKP G+L GH ASV  VQF   R  L SFSKDK+LR+WD+Q Q+ IQR A  FPK Q+      + E   RLFI+FN  L +L MK +   ++ SHEK +   LYNS+  QV+++  G  +  WM+DTGQ++K  T  C   AE++ +  D+ +TRL TG+TDG VKIWDFNG+C++TL V     VDISQI+ILK+ +LV G+ ++IT F   +F    + P  WKG   H DDIL  A +PP  + TGSYDGEI++WN ++E A   +    Q  +K
Sbjct:    1 MAWREKSKKRLNMTSFNIAQGIHAFDYHSRLNLIATAGINNKVCLWNPYVVSKPVGVLWGHSASVIAVQFFVERKQLFSFSKDKVLRLWDIQHQLSIQRIACSFPKSQDFRCLFHFDEAHGRLFISFNNQLALLAMKSEASKRVKSHEKAVTCVLYNSILKQVISSDTGSTVSFWMIDTGQKIKQFTG-CHGNAEISTMALDANETRLLTGSTDGTVKIWDFNGYCHHTLNVGQDGAVDISQILILKKKILVTGWERAITVFRPQNFNQFFIQPEEWKGGIQHHDDILCAAFLPPQTLVTGSYDGEIVLWNNSTENAHHVLHPDYQRLLK 329          

HSP 2 Score: 197.208 bits (500), Expect = 7.924e-52
Identity = 123/333 (36.94%), Postives = 178/333 (53.45%), Query Frame = 3
Query: 2355 ISRLIYLESRKKIKHGGGANLISCGGNGIVRFWNSAEGWLIGEFVAHENASNIIMNTDVSNQYLVTGDMDGYIRVWDILSYCQTESENQKIMSPPTLISQWQSHSDEISGISFCFKFSRTLIITSSADQSAALWELNGVLIGRFGQEHRWKLGSXXXXXXXXXXXXHEDEVVKQEEDKYKVDPNWYPDPEAIQNP-----SGYRINTWKDTNLGKDYQELRVRKRERIQPSSIPDLPYLYGEKIGRPTFGPFYSLNISSFEEIEDIEQPEFMEYPEKFF-NETEEFLTKTARVPLLNETLKAVFDERSLLPEYILEFEHKFRNRFQRHLSEAK 3335
            + RL +L++RK     GGANL+SCGG+G VRFW+  +  L+ EF+AH    +IIM+TD  N+YL TGD+DG++++W+I  YC   S+N KI   PTLI  +Q H D IS +  C    + LII+SSAD S  +  +    +  FGQ   W + + +  P        E E+ K+     K +    P   ++ N      S Y +   +D NL   Y+E     +E  +P         YGE I + +F  F SLNI + EE+ ++ +P F+  PEK+F  E EE   +    P L +TLKAVFDE++L P+ IL  E K +   Q    E K
Sbjct:  372 VMRLCFLKARKNTAVTGGANLVSCGGSGYVRFWDIYKKQLLAEFLAHSGVGSIIMSTDKMNRYLTTGDLDGWLKIWNIEEYCLNSSKN-KITKAPTLIRSFQPHEDRISSLEMCEPGGQLLIISSSADCSICVTGVCNAPVWIFGQAKHWHIENCLFLPKRDTNLV-ESEIQKEISLFSKEESCLDPTEHSLLNKKNKDDSTYNVRPSEDINLDIKYKERSTCMKETQKP--------YYGEVI-KKSFSTFRSLNIGALEELPEVNKPAFLLDPEKYFRKEPEEERPQILEAPSLFKTLKAVFDEKNLFPKEILHHERKAKQLCQEKSCEVK 693          
BLAST of WD repeat-containing protein 49 vs. Ensembl Human
Match: EFCAB8 (EF-hand calcium binding domain 8 [Source:HGNC Symbol;Acc:HGNC:34532])

HSP 1 Score: 286.189 bits (731), Expect = 1.745e-78
Identity = 248/967 (25.65%), Postives = 432/967 (44.67%), Query Frame = 3
Query:  201 NRSQHFNGEEFVEALSLVLCKGTREEYSDLFDKIDITREGYVDWEKFASHMLLEFYEKDDRTKSS-SLPQWKELKTLSGPHK-DVIQRIVLVRNLNR---YLTISKEGNVGLWGSDCKLQKVAK-THTESCRSRDLWVTDFAFLGNVNKVAVSFTSKEISFYDMNVKLEFNC--QVKLENLFRIPICMDYWHHPDNNGEAIMAWGDTGGYINVILWSNISSSLF-ERVSSKASDKDENTXXXXXXXXXXXXXKTCTYFSHKAHQDWVRKVSYIPNLECFVSCATNWNTSMVICWMEKYNPSNSTSSEMAGIPESRGFSRTSCFTVHQGINSFAYNENLNLIATAGVNFQVCLWNPYVISKPNGLLRGHMASVTDVQFN-KARGHLISFSKDKILRIWDVQLQVCIQRYAG-VFPKGQ-EMYSKMFYHEEKLRLFITFNFGLT--MLEMKPDVK-DKISSHEKPLIGCLYNSLYNQVVTACQGGIIYCWMVDTGQRVKTITEICGPQAELTCITQDSTQTRLYTGATDGNVKIWDFN-GHCYNTLIVANGNPVDISQIVILKRCVLVFGFSKSITAFWTSSFKDHKVSPS----PWKGVQTHKDDILSGASIPPHAVATGSYDGEIIIWNIN-------------------------------SEQASRTMTQRSQDEMKEVKKLAEQTIVRIKMAANAELKR---AASNSIQQETDDKLDFIKAEIQNSIAN--RQXXXXXXXXXXXXXXXXXXXXDTVSDMQVQYKKMDVMFNISRLIYLESRKKIKHGGGANLISCGGNGIVRFWNSAE-GWLIGEFVAHENASNII---MNTDVSNQYLVTGDMDGYIRVWDILSYCQT------ESENQKIMS--------------------------------------PPTLISQWQSHSDEISGISFCFKFSRTLIITSSADQSAALWELNGVLIGRFG 2789
            N +     + F++A+  VL   + E   +LF K+D   EG+V W+K+  +M+ EF  K+D  KS   L  +  +  +   H  +V++ + L+    +   +LT++K+G +  W     L    +   T+   ++ +WV D   L N+N VAV+ T ++I F+D++   +  C       +L    + MDYW    +    +  +GD  G + V    N++S LF  R+  +AS  D    +     +   S    +Y     H +W  +V +IP +   VSC+    +S+V+  +    P+ ++              R S   + +GI  F Y  + N + T G +  + LWNP+V  +P  L++GH  SVT +  + +    LIS SKDK +R+WD+   +C+Q + G  F  G   + S  F+ ++   +  T++ G+    LE +  +K  K ++H  PL   LY+ ++ QVV+ C  G +  W V TG++        G   E+T +  D ++  L TG  DG +K+W++N G C   L   +   ++IS I+ + +   V G+SK IT F       HK  P      W+    H +DILS A      + T SY G+I+ WN                                 S + SR   +R +   K  +KL+    +  +  AN  L+R   +A   ++   D + D    + + S A+   +    I +  S  +   +   +   +M VQ        ++ ++I+L++R ++ H   A L+S   +G +  W+  E G L+G+F    +  +++   M TD ++  L+TGD  GYI++WDI  YC        +S   K++S                                      PPTL+  W+ H + ++ I +   F   L+I++  D+    W+L+G  IG FG
Sbjct:   66 NSTGALGMDAFIKAMKKVLSSVSDEMLKELFLKVDSDCEGFVTWQKYVDYMMREFQGKEDMRKSQYRLHFYLPMTVVPLNHGCEVVKVVFLIHRFKKIGCFLTVTKDGILQFWSESFSLMSSFRLNQTQQLYNQPMWVIDMVCLHNMNLVAVASTRQKIDFFDIS---DHKCVRAFTFVDLDSCALVMDYW---SDYHRGVFCYGDAKGNVIVFTSENMTSGLFNPRILPRASKWDHWIKVSLQKLLNEKSALHRSYRLKALHPNWCEQVKFIPQMNVVVSCSAIEKSSLVLTIL----PAKASKKP-----------RLSVLRLRKGILCFDYCPDRNFLVTGGYDAFIRLWNPFVSKRPVWLMKGHQTSVTHILVDSRNNSILISVSKDKNIRVWDMLDYICLQSFCGKFFALGNCPITSAYFFEKDNTLICSTYSIGILKGYLEAQGLIKARKRTTHCSPLCAVLYSKIFKQVVSGCLRGTVSVWEVVTGRKTMEFAVSGGQHVEMTAMALDESERCLLTGLRDGTMKMWNYNIGKCL--LTFPSPEQLEISGIIHMNKVFYVTGWSKRITHFLF-----HKTKPVLLCYHWQTY--HTEDILSMAKYRNQFLGTSSYSGDILFWNTGTLKPIFNFNASRSPSPLQPKRVQDVNNCLAESHRPSRPYVEREKWTYKTSRKLSS---LSPESVANTNLRRSLVSAPPVMRCPRDKEPDRPVPQQKPSSASGTSRQSSKIHSKQSIYKEDETRKGEWQKNMLVQSSA-----SVEKIIFLQTRPRLPH--TAALLSSCMDGYIYAWSLHENGGLLGKFPVDLDNGDVVVGAMATDKNDWILITGDCKGYIKIWDIKDYCALIDKQPFQSSGAKVVSEAHNKFRLLIPQQLGTNFPHYIPLEDKEVVAGHTISLVPPTLLMTWKGHLNSVADILYVDNFQ--LVISAGQDRDVKAWKLSGDAIGTFG 990          
BLAST of WD repeat-containing protein 49 vs. Ensembl Celegans
Match: snrp-40.2 (Small Nuclear RibonucleoProtein homolog [Source:UniProtKB/TrEMBL;Acc:O02097])

HSP 1 Score: 58.9214 bits (141), Expect = 9.180e-9
Identity = 31/109 (28.44%), Postives = 60/109 (55.05%), Query Frame = 3
Query: 1077 NSTSSEMAGIPE--SRGFSRTSCFTVHQG-INSFAYNENLNLIATAGVNFQVCLWNPYVISKPNGLLRGHMASVTDVQFNKARGHLISFSKDKILRIWDVQLQVCIQRY 1394
            N  +S+   +P+  S   + T     H G I +  ++ + + +A+AG + Q+ LWN +   +   +L+GH  ++ +V+FN    HL+S   DK +R+WD++   CI+ +
Sbjct:    9 NQMASQFLELPKRTSSLMAPTMVLQGHGGEIYTSQFSSDGSFLASAGYDQQIFLWNVFGECENFAVLKGHKGAIMEVKFNADSSHLVSAGTDKTVRVWDMETGSCIRNF 117          
BLAST of WD repeat-containing protein 49 vs. Ensembl Celegans
Match: snrp-40.1 (Small Nuclear RibonucleoProtein homolog [Source:UniProtKB/TrEMBL;Acc:Q19211])

HSP 1 Score: 52.7582 bits (125), Expect = 1.008e-6
Identity = 24/83 (28.92%), Postives = 47/83 (56.63%), Query Frame = 3
Query: 1149 HQG-INSFAYNENLNLIATAGVNFQVCLWNPYVISKPNGLLRGHMASVTDVQFNKARGHLISFSKDKILRIWDVQLQVCIQRY 1394
            H+G I + A++ +   +AT+G + ++  WN Y   +    ++GH  +V D++F      L+S   DK +R+WD++   C +R+
Sbjct:   37 HEGEIYTGAFSPDGTCLATSGYDQKIFFWNVYGECENFSTIKGHSGAVMDLKFTTDSSSLVSCGTDKSVRVWDMETGTCARRF 119          
BLAST of WD repeat-containing protein 49 vs. Ensembl Celegans
Match: F13H8.2 (pep chromosome:WBcel235:II:6270370:6274005:1 gene:WBGene00017435.1 transcript:F13H8.2.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:F13H8.2)

HSP 1 Score: 51.9878 bits (123), Expect = 3.302e-6
Identity = 34/124 (27.42%), Postives = 60/124 (48.39%), Query Frame = 3
Query: 1140 FTVHQ-GINSFAYNENLNLIATAGVNFQVCLWNPYVISKPNGLLR--GHMASVTDVQFNKARGHLISFSKDKILRIWDVQLQVCIQRYAGVFPKGQEMYSKMFYHEEKLRLFITFNFGLTMLEM 1502
            F+ H+  +N   ++ +  L AT G +  + LW+   I    G+ R  GH  SVT ++F +    +IS SKD +++ W +  Q C   +  V     E+YS   + +E + +  T    L + E+
Sbjct:   99 FSGHKKAVNCIEFSSDGLLFATGGKDGVIVLWD---ILAERGMFRLHGHKESVTQMKFVRGDRFIISTSKDSLIKFWSIASQSC---FYTVMDSRNEIYSMSLHRDETVLVAATAELELLVFEL 216          
BLAST of WD repeat-containing protein 49 vs. Ensembl Fly
Match: WDY (gene:FBgn0267449 transcript:FBtr0347028)

HSP 1 Score: 160.229 bits (404), Expect = 2.367e-39
Identity = 142/607 (23.39%), Postives = 256/607 (42.17%), Query Frame = 3
Query: 1122 FSRTSCFTVHQGINSFAYNENLNLIATAGVNFQVCLWNPYVISKPNGLLRGHMASVTDVQFNKARGHLISFSKDKILRIWDVQLQVCIQRYAGVFPKGQEMYSKM-FYHEEKLRLFITFNFGLTMLEMKPDVKDKIS---SHEKPLIGCLYNSLYNQVVTACQGGIIYCWMVDTGQRVKTITEICGPQA--------ELTCITQDSTQTRLYTGATDGNVKIWDFNGHCYNTLIVANGNPV---DISQIVILKRCVLVFGFSKSITAFWTSSFKDHKVSPSPWKGVQTHKDDILSGASIPPHAVATGSYDGEIIIWNINSEQASRTMTQRSQDEMKEVKKLA-EQTIVRIKMAANAELKRAASNSIQQETDDKLDFIKAEIQNSIANRQXXXXXXXXXXXXXXXXXXXXDTVSDMQVQYKKMDVMFNISRLIYLESR-KKIKHGGGANLISCGGNGIVRFWNSAEGWLIGEFVA-HENASNII-MNTDVSNQYLVTGDMDGYIRVWDILSYCQTESENQKIMSP---------------------------PTLISQWQSHSDEISGISFCFKFSRTLIITSSADQSAALWELNGVLIGRFGQEHRW 2804
            +   S F +  G+++F   E+ N++ T G +  V +W+ Y+ ++P+ +L GH   +  V        + S    KI+++WD+     +Q Y  +        + + +Y+   LR  +     L  ++  P V+  ++   +H  P+   LYN L+  +V+      I  W   TG+R K I + C  +         E+T    D  +  L TGA DG++KIW++N    N ++V N + +   +++ ++ +   +L  G+ + +T F     +++   P  W   + H DDI          V T +Y GEII W + + Q  R  +        E+K  A E+  +R      + L  + ++S+Q     +         +++ NR  +     +                         D+  ++  +++L++R + +KH  G+  IS     I  + +   G  I EF+A H+    ++ M TD  N+YL TG   GYI+VW I+++C  ESE   +  P                           P L+S ++ H   I+ I+F       +I T S D S  LW   G  +G  G    W
Sbjct:  315 YDERSNFRIPLGVSTFFVAESHNIVVTGGPDTFVRIWDVYIPTEPSAILTGHNGGIVLVFVQPEENKVYSVDYQKIIKVWDLHEHTLLQTYGDLVRLIHHSETDLTYYYHSHLRELVVAGRKLISIKCCPRVRVDLTDGNTHAAPVSVVLYNRLFRNIVSCGLDSYIIVWDPWTGRR-KIIMKSCHTKMIYGEIIDIEITAACFDPLEQFLLTGARDGSLKIWNYN----NAVVVRNMSIMPDQEVTAVIWVVDRILAMGWDRQVTEFNDVVGREYG-DPKKWP--KFHTDDITCADVKLGEGVVTATYSGEIIFWKLETGQPYRRYSVMDPTRFIELKLTAEEEKFIRQSKRLASRLTHSGNHSLQTGRAGR---------STVLNRPEDNRDYGT-------------------------DIPISVQAVLFLQTRPQTLKH--GSVFISLDTGFIQVYSHHQRGGYIVEFLAVHKTGDCVLTMCTDRKNRYLYTGTAFGYIKVWYIVNFCVPESEKTHVCMPKLRLEFIFLRKELFMTRAKRAVRNQAEPLLVSSYKGHLKAINSIAFINL--PKIIFTGSHDYSCRLWTQGGRYLGTLGTVLPW 875          
BLAST of WD repeat-containing protein 49 vs. Ensembl Zebrafish
Match: wdr95 (WD40 repeat domain 95 [Source:ZFIN;Acc:ZDB-GENE-131127-243])

HSP 1 Score: 239.195 bits (609), Expect = 1.488e-64
Identity = 203/674 (30.12%), Postives = 324/674 (48.07%), Query Frame = 3
Query:  144 LNIKDLETLQEAF--FMDGSHNRSQHFNGEEFVEAL-SLVLCKGTREEYSDLFDKIDITREGYVDWEKFASHMLLEFYEKDD---RTKSSS--LPQWKELKTLSGPHKDVIQRIVLVRNLNRYLTISKEGNVGLWGSDCKLQKVAKTHTE-SCRSRDLWVTDFAFLGNVNKVAVSFTSKEISFYDMNVKLEFNCQVKLENLFRIPICMDYWH-HPDNNGEAIMAWGDTGGYINVILWSNISSSLFERVSSKASDKDENTXXXXXXXXXXXXXKTCTYFSHKAHQDWVRKVSYIPNLECFVSCATNWNTSMVICWMEKYNPSNSTSSEMAGIPE------SRGFSRTSC----FTVHQGINSFAYNENLNLIATAGVNFQVCLWNPYVISKPNGLLRGHMASVTDVQFNKARGHLISFSKDKILRIWDVQLQVCIQRYAGVFPKGQEMYSKMFYHEEKLRLFITFN-FGLTMLEMKPDVKD-KISSHEKPLIGCLYNSLYNQVVTACQGGIIYCWMVDTGQRVKTITEICGPQAELTCITQDSTQTRLYTGATDGNVKIWDF-NGHCYNTLIVANGNP--VDISQIVILKRC-VLVFGFSKSITAFWTSSFKDHKVS-PSP-WKG--VQTHKDDILSGASIPPHAVATGSYDGEIIIWNINSEQ-ASRTMTQRSQ 2072
            ++I DL+ +++AF  F     +   +   +  + +  SL   K T+ ++  LF KID T +G ++W +  +++ LE  +K++   R+K ++  LP   +      P    + RI    N    +T+ ++G V  W     L+       E S   R  W TDF  +   NK+ ++  S+E+ FY+ +  LE  CQ  L  L  +P+ +DY    PD   E ++ +GDT G +N++L  +I   L     S   D   N  I    +         T+   K HQDWV KV Y  ++   VS + +  T++VI      +PS     +M G  E      ++   R +C    F V +G+ +F   +NLNL+ T G++  V +W PYV   P G+L+GH A V  V      GH+ S S D   +IW ++ Q C+        + +   S   Y      L+I  +   L  L+ KP  K  +I SH++P++ C Y+  + QVV+  +G +I  W V+TG  +       G  A +TC+T D++  RL TG  DG +K+W+F NG C   L      P   D S + +     V+  G+S+ I  +  S  +   +  P+P W+      HK+DIL  A   PH +ATGS+DGEII+WN+ S +   R  T +SQ
Sbjct:    2 VSINDLKHIKQAFDEFAKAGIDMLDYAEFQTVMRSCPSLKTVKDTQIQH--LFMKIDYTGDGKIEWHEICTYIFLENKKKEETVHRSKMAAFVLPAIVKFLNCGEP----LLRIHFPPN-GTVVTLREDGLVSFWTPKLHLKSKKNLFPERSITRRPNWATDFVLMPEYNKLIIATGSRELQFYEFS-SLEPCCQ--LSALETVPLNLDYCSTRPD---ECVIVYGDTEGCVNILLMKSIREKLRLWKRSPQVDNIPNISIDHAVES-----PEVTFIRWKVHQDWVSKVKYFESISSIVSSSAHEETALVI---GSIHPSTYKQEQMRGTAEVSDERSTKVTQRATCNQTIFIVPKGVTTFDLCKNLNLLVTGGMDKVVRMWIPYVPRNPTGILKGHSAPVAYVCVTSENGHIYSVSTDNTAKIWHIKDQTCLFTAHPNSSQIKGELSACIYSSAAKGLYIASDSIALLSLKTKPQPKGIQIVSHKEPVLCCGYSEQFRQVVSCSEGSVIKIWDVETGALIFEFGCAHGDSA-ITCMTFDTSGRRLMTGGRDGLIKLWNFNNGQCVKILSREGKCPEICDCSYLTLHGNTFVISVGWSRRIDIYLDSKEETQFIQRPTPSWQDDMRNGHKEDILCIAHCTPHLLATGSFDGEIIVWNVVSGRIQCRFQTPQSQ 653          

HSP 2 Score: 74.7146 bits (182), Expect = 5.741e-13
Identity = 50/159 (31.45%), Postives = 79/159 (49.69%), Query Frame = 3
Query: 2352 NISRLIYLESRKKIKH-GGGANLISCGGNGIVRFWNSAEGWLIGEFVAHENASNI-----IMNTDVSNQYLVTGDMDGYIRVWDILSYCQTESENQKIMSPPTLISQWQSHSDEISGISFCFKFSRTLIITSSADQSAALWELNGVLIGRFGQEHRWKL 2810
            ++  LI+L++R  +      A L+S G  G V FW+   G   G+FVA   AS++      +     +  L T D  G+I V+++  Y     +N     PP  I+ W++H   I+G+    K     ++TSS D S  LW ++G  IG FGQE  W++
Sbjct:  664 SVLSLIFLKTRAFVPELASSAWLVSSGSRGYVNFWSVLNG---GKFVASFQASHLQQQITKLALTQDDSMLFTADHVGFIYVYNVKQYAMGPEQN-----PPEKINFWRAHIRSITGLKIVDK--DQFLLTSSMDCSVRLWNIHGDYIGTFGQEEDWRI 812          
BLAST of WD repeat-containing protein 49 vs. Ensembl Zebrafish
Match: si:dkey-202c14.3 (si:dkey-202c14.3 [Source:ZFIN;Acc:ZDB-GENE-121214-357])

HSP 1 Score: 181.415 bits (459), Expect = 7.856e-46
Identity = 174/671 (25.93%), Postives = 291/671 (43.37%), Query Frame = 3
Query:  129 KLELKLNIKDLETLQEAFFMDGSHNRSQHFNGEEFVEALSL-------VLCKGTREEYS-----DLFDKIDITREGYVDWEKFASHMLLEF-YEKDDRTKSSSLPQWKEL--KTLSGPHKDVIQRIVLVRNLN-RYLTISKEGNVGLWGSDCKLQKVAKTHTESCRSRDL------WVTDFAFLGNVNKVAVSFTSKEISFYDMNVKLEFNCQVKLENLFRIPICMDYWHHPDNNGE-AIMAWGDTGGYINVILWSNISSSLFERVSSKASDKDENTXXXXXXXXXXXXXKTCTYFSHKAHQDWVRKVSYIPNLECFVSCATNWNTSMVICWM----EKYNPSNSTSSEMAGIPESRGFSRTSCFTVHQGINSFAYNENLNLIATAGVNFQVCLWNPYVISKPNGLLRGHMASVTDVQFNKARGHLISFSKDKILRIWDVQLQVCIQRY--------AGVFPKGQEMYSKMFYHEEKLRLFITFNFGLTMLEMKPDVKDKISSHEKPLIGCLYNSLYNQVVTACQGGIIYCWMVDTGQRVKTITEICGPQAELTCITQDSTQTRLYTGATDGNVKIWDFNGHCYNTLIVANGNPVDISQIVILKRCVLVFGFSKSITAFWTSSFKDHKVSPS-PWKGVQTHKDDILSGASIPPHA-VATGSYDGEIIIWNI 2030
            +L   L    L    E+FF   S + S+     E V A S+        L + T ++Y      D F+++ I+ +G V+W+ F + ML  + +         +LP    L  K      + +++ + L R+   RY+++SK G +  W       K  +   E+   R        WVTD  ++ NV+K+AV+  ++ I F+D+     F  Q+ L  L      + YW+  +  GE  ++ WGD  G +N++ +      LF    +  S   + ++          S +       K H   + ++ Y P  +  ++ + +  +++VI  +    EKY                        + + +G+  F ++ +L L+ TAGV   V LWN YV S+P  +LR H  +V DV  ++A G + S+SKD +L+IWD+  Q C++          AGV P+ Q  +  +        L +T    + +L++    K +  S        LYN    QV  AC    +  W V TG R   I    G + E++C+  D  Q RL T AT+G +K+W+         +    N      I      +L  G+S+ IT +  +   D  +  +  WK    H +DIL+    P    +ATGSYDGEIIIW +
Sbjct:   31 RLLESLQSNHLSLFMESFFRQRS-DPSRRVRASERVSANSMSFEDYFCCLKEATGQDYQRSDVEDFFNEMSISCDGRVEWQTFQTFMLQHYKHITQSMQPCQNLPISHPLIRKCTYNKQEAIVRVLALTRSPPMRYVSVSKRGTLIAWNRHLNHLKPLEMWGEAFNKRHHRKRFQGWVTDAVYMANVHKIAVATLNRGIHFFDVTTASGFE-QIHLYGLTHFASALCYWYETEAPGEKCVLMWGDEKGSVNLLWFLQPFKGLFAMPFTIQSGPVKISLQDIYMHSALASYQHIP----KIHSMLINRILYEPRDDIIITSSDSSASAVVIIDVNQKREKY-----------------------VWRIEKGVKCFDFSCSLGLLVTAGVGPAVRLWNRYVTSRPTAVLRSHQTTVVDVVIHQALGKIFSYSKDAVLKIWDIPSQQCVKTLHLNFPNIQAGVSPE-QGSFPLLLNLSSDPVLLVTCREYVALLQLD---KTETRSRSDLYTCALYNPHLQQV--ACADSTLTVWDVKTGIRRMEIRNAHGNE-EVSCMALDVHQRRLITAATNGTIKVWNLLNGLNLHNLEPVSNKEVTGIICHHDDQLLATGWSRLITQYSIAFSSDIYIKANLSWKSGCQHSEDILAMDHCPVLGLLATGSYDGEIIIWAL 665          

HSP 2 Score: 80.1073 bits (196), Expect = 1.392e-14
Identity = 50/159 (31.45%), Postives = 73/159 (45.91%), Query Frame = 3
Query: 2343 VMFNISRLIYLESRKKIKHGGGANLISCGGNGIVRFWN-SAEGWLIGEF-VAHENASNII-MNTDVSNQYLVTGDMDGYIRVWDILSYCQTESENQKIMSPPTLISQWQSHSDEISGISFCFKFSRTLIITSSADQSAALWELNGVLIGRFGQEHRWKL 2810
            V   + RL++L+SR +  H   A ++     G V  W+        G+F V  ++  N+   +TD  N  LVTGD  G I+VWDI  Y     + +     P L+  W  H   I         SR  I++ S D+ A LW   G  +G FG+E +W L
Sbjct:  677 VHLPVHRLLFLQSRAQQSHLRKAAVLLSSQAGFVCCWSVCGPRHNHGQFYVPDKSGENVTGFSTDPENNLLVTGDTTGCIKVWDIAQYALNNGDMESAAGFPPLLHSWSGHERAIVSSEVLLYESRFFILSVSMDRRACLWTHEGSCVGCFGEEQQWDL 835          
BLAST of WD repeat-containing protein 49 vs. Ensembl Zebrafish
Match: wdr5 (WD repeat domain 5 [Source:ZFIN;Acc:ZDB-GENE-040426-2082])

HSP 1 Score: 58.151 bits (139), Expect = 3.186e-8
Identity = 44/212 (20.75%), Postives = 95/212 (44.81%), Query Frame = 3
Query: 1152 QGINSFAYNENLNLIATAGVNFQVCLWNPYVISKPNGLLRGHMASVTDVQFNKARGHLISFSKDKILRIWDVQLQVCIQRYAGVFPKGQEMYSKMFYHEEKLRLFITFNFGLTMLEMKPDVKDK-ISSHEKPLIGCLYNSLYNQVVTACQGGIIYCWMVDTGQRVKTITEICGPQAELTCITQDSTQTRLYTGATDGNVKIWDFN-GHCYNT 1781
            + ++S  ++ +   +A++  +  + +W  Y   K    + GH   ++DV ++     L+S S DK L+IWDV    C++   G       ++   F  +  L +  +F+  + + ++K     K + +H  P+    +N   + +V++   G+   W   +GQ +KT+ +   P       + +     +     D  +K+WD++ G C  T
Sbjct:   46 KAVSSVKFSPSGEWLASSSADKLIKIWGAY-DGKFEKTISGHKLGISDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKG---HSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNG--KYILAATLDNTLKLWDYSKGKCLKT 251          
BLAST of WD repeat-containing protein 49 vs. Ensembl Zebrafish
Match: taf5 (TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor [Source:ZFIN;Acc:ZDB-GENE-051120-180])

HSP 1 Score: 53.1434 bits (126), Expect = 2.752e-6
Identity = 46/181 (25.41%), Postives = 74/181 (40.88%), Query Frame = 3
Query: 1248 SKPNGLLRGHMASVTDVQFNKARGHLISFSKDKILRIWDVQLQVCIQRYAGV-FPKGQEMYSKMFY------HEEKLRLFITFNFGLTMLEMKPDVKDKISSHEKPLIGCLYNSLYNQVVTACQGGIIYCWMVDTGQRVKTITEICGPQAELTCITQDSTQTRLYTGATDGNVKIWDFNGH 1769
            S  + +L GH   V  V F+  R +L+S S+D  +R+W +Q   C+  Y G  +P     +S   Y      H+   RL+ T ++    +          + H   +    ++   N V T      +  W V  G  V+  T   GP   +  +        L +G+TDG V +WD  GH
Sbjct:  489 SSESKILHGHSGPVYGVSFSPDRNYLLSSSEDGTIRLWSLQTFTCLVGYKGHNYPVWDTQFSPFGYYFVSGGHDRVARLWATDHYQPLRI---------FAGHLADVTCTRFHPNSNYVATGSSDRTVRLWDVLNGNCVRIFTGHKGP---IHSLAFSPNGKFLASGSTDGRVLLWDI-GH 656          
BLAST of WD repeat-containing protein 49 vs. Ensembl Xenopus
Match: wdr49 (WD repeat domain 49 [Source:NCBI gene;Acc:549615])

HSP 1 Score: 757.288 bits (1954), Expect = 0.000e+0
Identity = 411/1068 (38.48%), Postives = 616/1068 (57.68%), Query Frame = 3
Query:  132 LELKLNIKDLETLQEAFFMDGSHNRSQHFNGEEFVEALSLVLCKGTREEYSDLFDKIDITREGYVDWEKFASHMLLEFYEKDDRTKSSSLPQWKELKTLSGPHKDVIQRIVLVRNLNRYLTISKEGNVGLWGSDCKLQKVAKTHTESCRSRDLWVTDFAFLGNVNKVAVSFTSKEISFYDMNVKLEFNCQVKLENLFRIPICMDYWHHPDNNGEAIMAWGDTGGYINVILWSNISSSLFERVSSKASDKDENTXXXXXXXXXXXXXKTCTYFSHKAH-QDWVRKVSYIPNLECFVSCATNWNTSMVICWMEKYNPSNSTSSEMAGIPESRGFSRTSCFTVHQGINSFAYNENLNLIATAGVNFQVCLWNPYVISKPNGLLRGHMASVTDVQFNKARGHLISFSKDKILRIWDVQLQVCIQRYAGVFPKGQEMYSKMFYHEEKLRLFITFNFGLTMLEMKPDVKDKISSHEKPLIGCLYNSLYNQVVTACQGGIIYCWMVDTGQRVKTITEICGPQAELTCITQDSTQTRLYTGATDGNVKIWDFNGHCYNTLIVANGNPVDISQIVILKRCVLVFGFSKSITAFWTSSFKDHKVSPSPWKGVQTHKDDILSGASIPPHAVATGSYDGEIIIWNINSEQASRTMTQRSQDEMKEVKKLAEQTIVRIKMAANAELKRAASNSIQQETDDKLDFIKAEIQNSIANRQXXXXXXXXXXXXXXXXXXXXDTVSDMQVQYKKMDVMFNISRLIYLESRKKIKHGGGANLISCGGNGIVRFWNSAEGWLIGEFVAHENASNIIMNTDVSNQYLVTGDMDGYIRVWDILSYCQTESENQKIMSPPTLISQWQSHSDEISGISFCFKFSRTLIITSSADQSAALWELNGVLIGRFGQEHRWKLGSXXXXXXXXXXXXHEDEVVKQEEDKYKVDPNWYPDPEAIQNPS-------------GYRINTWKDTNLGKDYQELRVRKRERIQPSSIPDLPYLYGEKIGRPTFGPFYSLNISSFEEIEDIEQPEFMEYPEKFF-NETEEFLTKTARVPLLNETLKAVFDERSLLPEYILEFE 3290
            +E +L+IKD   +Q   F     N+S+  + EEF+E     +  G +EEY +LFDKID++REG++DW+K  S MLLE  EKD+R KSS +PQWK++++    H + IQ+IV ++ L RY+T+SK+G +G+WG + KLQ+  +  T++ + +DLW T   FL NVNK+AVSFTSKEI FYD+N K +  CQ KL  L   PICMDYW++PD+  +A++ +GD  G +  + ++    SLFER ++   D+ + T+ I+ N++I G  K+C    HK H  +WVR+V+Y  +LE F+SC T+ N ++++ W EK                 +   R +   + +GIN F Y+  LN+IATAG++ ++CLWNPYVISKP G+L+G+MASV  VQF   R  L SFSKDK+LRIWDV  QVCIQR AG+FPK  E +  +++ E   RLF++FN  L +LEMK +   KI+SHEKP+   LYNS + QV+++  G  I  WM+DTGQ++K  +  C   +E++ +  D ++TRL TG+TDG VKIWDFNGHC++ L        +ISQI++LKR +LV G+ + IT F  +    + + PS WKG   H DDIL  A   P ++ TGSYDG+I+IWN N+E ASR +    +               R+K  ++++++ A   S+   +  K     + I N+ ++                                       +++RL +L +RK     GG+ L+SCGG+G VRFWN     L+ EFVAHE A +IIM  D +NQY++TGD+DG+++VWDI  YC   SE +K   PP L+  +Q HSD ++ +  C      LI+++SAD +  + ++ G  +G FGQE  W +   +       +  + +       +K  V    Y D       +              ++I+ W++T LGK Y++   +++          L     E   + + G F  LNI    ++ D+ +P+F+  PEK+F ++T+E  TK    P L++TLK+VFDE SL P  ILE E
Sbjct:   36 IENRLSIKDFGQIQR-LFQSPELNQSECMSREEFMERTYAAVGHGIKEEYGELFDKIDVSREGFIDWDKLTSFMLLELNEKDERVKSSVIPQWKDIRSFPLIHTENIQKIVYLKGLGRYVTLSKDGLLGVWGENLKLQRSLQICTDTVKLKDLWATSLVFLANVNKIAVSFTSKEICFYDLNSKQDLFCQYKLHGLPGTPICMDYWYNPDDGNDAVLTFGDVNGQVQAVCFTTAMISLFERPANSTEDQ-QTTLYITWNELISGYHKSCFIAKHKLHGNNWVRQVTYSSHLEAFLSCTTSDNNTVILAWREK----------------GKTHLRATSLNIAKGINGFDYHAGLNMIATAGIDNKICLWNPYVISKPTGILQGNMASVITVQFFTGRKQLFSFSKDKVLRIWDVHHQVCIQRVAGIFPKSLEFHFTLYFCEPHGRLFVSFNNQLKLLEMKKESGSKITSHEKPITCVLYNSTFKQVISSDTGSTITFWMIDTGQKIKQFSG-CHGTSEISTMALDVSETRLLTGSTDGTVKIWDFNGHCHHKLNAGRDQAAEISQILVLKRTILVVGWERIITVFRFNLLTQYLIQPSEWKGGVQHHDDILCAAFYLPQSLVTGSYDGQIVIWNNNTENASRKLHPDPE---------------RLKSRSDSQVRSAGRRSLSSLSSGKHSRSASSIHNANSDSNN------------------------------------SVTRLFFLGARKNTSATGGSILVSCGGSGYVRFWNIFRNHLMAEFVAHEGAGSIIMTVDKTNQYIITGDLDGWLKVWDIQDYCIDYSE-KKTTDPPQLVKSFQPHSDCVTHLETCAYSQSLLILSASADCTIHVSDVFGTPVGIFGQEEHWSIEKCLHENERNHVSENSEGDTSHTNNKESVTSTTYCDETTELGDTLSSSLLTEDKEELPFKISPWENTILGKKYKDFGTKEK----------LHSNRREDSVQTSVGTFMLLNIEPLLDVADVTKPDFVINPEKYFEDKTDEKSTKEFTTPPLSDTLKSVFDEGSLFPREILERE 1022          
BLAST of WD repeat-containing protein 49 vs. Ensembl Xenopus
Match: ENSXETT00000013976.1 (EF-hand calcium binding domain 8 [Source:NCBI gene;Acc:100494912])

HSP 1 Score: 220.705 bits (561), Expect = 8.604e-59
Identity = 180/704 (25.57%), Postives = 316/704 (44.89%), Query Frame = 3
Query:  129 KLELKLNIKDLETLQEAFFMDGSHNRSQHFN--------------------GEEFVEALSLVLCKGTREEYSD-----LFDKIDITREGYVDWEKFASHMLLEFYEKDDRT--KSSSLPQWKELKTLSGPHKDVIQRIVLVRNLNR--YLTISKEGNVGLWGSDCKLQK---VAKTHTESC---RSRDLWVTDFAFLGNVNKVAVSFTSKEISFYD---MNVKLEFNCQVKLENLFRIPICMDYWHHPDN-NGEAIMAWGDTGGYINVILWSNISSSLFERVSSKASDKDENTXXXXXXXXXXXXXKTCTY-FSHKAHQDWVRKVSYIPNLECFVSCATNWNTSMVICWMEKYNPSNSTSSEMAGIPESRGFSRTSCFTVHQGINSFAYNENLNLIATAGVNFQVCLWNPYVISKPNGLLRGHMASVTDVQFNKARGHLISFSKDKILRIWDVQLQVCIQRYAGVFP-------KGQEMYSKMFYHEEKLRLFITFN--FGLTMLEMKPDVKDKISSHEKPLIGCLYNSLYNQVVTACQGGIIYCWMVDTGQRVKTITEICGPQAELTCITQDSTQTRLYTGATDGNVKIWDF-NGHCYNTLIVANGNPVDISQIVIL----KRCVLVFGFSKSITAFWTSSFKDHKVSPS-PWKGVQTHKDDILSGASIPPHA-VATGSYDGEIIIWNINSEQASRTMTQRSQ 2072
            +LE K  + DL  LQEAF    S  +  +                      G   ++    VLC     E  D     LF+++D + +GYVDW +F +++LL++ ++D R   + + L Q   ++  +   ++   RI+ + +      L++SK G +  W      QK   VA  + +S    R    WVTD   L N NK+A++ TS++I F+D   MN+  EF+    L  L  +P    YW++  +    +++ WG   G +NV+      + +FE+  S+     +          +    K  +Y      H + + K+ Y P  +  ++ + +  +S++I  + +                     +   + +++G+  F Y   LNL+ T G + +V LWN YV  +P  +L  H  ++ DV   +  G + SFSKD +L++WD+  Q C+      FP       + Q  +  +       RL + ++   G+  L      +    +H  P+   LY+S  + +VT  +   +  W V+TG +   +    G Q E+TC+  D  Q RL TGA +G +KIW+  NGH  + L      PV+ ++I  +    +   L  G+++ I  +      +  V  +  WKG Q H++DIL+    P    +AT S+DGEII+WN  +++    + Q  Q
Sbjct:   29 RLEEKFRLDDLRLLQEAFAKHNSDGKETNCKEESDDLRATRRRAKQEARPAGNMTLDEFRRVLCDLFGSECFDDDMELLFNEVDTSCDGYVDWGEFCTYLLLQYRKRDYRMIGRVTFLGQ-PVIRLCTRNKQEPTSRILAISSPPPMWLLSVSKTGVLTTWDLALHPQKSYEVAAEYPDSQAGKRRFKCWVTDAVHLPNANKIAIATTSRDIHFFDVSTMNLFEEFH----LFALNHVPTTFSYWYNKQSPESRSLLLWGGDNGAVNVLWLLQPQTGVFEKPFSQHPGPTK-----IYMQELKDHSKLLSYQVIPDVHPEAITKLIYCPEKQLIITSSGSAQSSLLIMDINQKG-------------------KVYTWKINKGVQCFDYCRALNLLVTGGFDHKVRLWNQYVTCRPIAVLPEHSMAILDVMIYQPLGQIFSFSKDSVLKVWDIPSQTCLHTLVLKFPCIQPGRIQEQGSFPFLLVPTNPSRLLVCYSDYIGILRLARAEPTEGTFFTHRAPVTCLLYSSFCHLIVTGSEDSTVAVWDVETGAKSLLLGNAHG-QEEVTCMALDKAQRRLITGARNGTIKIWNIQNGHNLHQL-----EPVEDAEITCIVASQENVFLTVGWNRKIVTYDIPKTNEVYVPANHSWKGGQLHQEDILTADFCPSLGLLATASFDGEIILWNAETQRLYLYLRQCPQ 697          

HSP 2 Score: 78.1814 bits (191), Expect = 7.749e-14
Identity = 47/157 (29.94%), Postives = 78/157 (49.68%), Query Frame = 3
Query: 2355 ISRLIYLESRKKIKHGGGANLISCGGNGIVRFW---NSAEGWLIGEFVAHENA--SNIIMNTDVSNQYLVTGDMDGYIRVWDILSYCQTESENQKIMSPPTLISQWQSHSDEISGISFCFKFSRTLIITSSADQSAALWELNGVLIGRFGQEHRWKL 2810
            + +L +L+ R   +    A ++     G +R+W   N  + W  G F A + A  S + + +D +N+ LV+GD  G ++VWDI +Y    +       PP L S W +H   +  +      S   I + S+D++A LW ++G  +G FGQ   WKL
Sbjct:  704 VDKLFFLQKRSAKRE---AAILVSSEAGTLRWWRVTNGGQEW--GSFYAQDEADCSVLGLASDKANRVLVSGDTLGLVQVWDISAYGLQAAAQTYTCRPPLLYS-WGAHDSAVVSVEHFLYDSEPFIASGSSDKTAKLWTVDGKQVGTFGQSKCWKL 854          
BLAST of WD repeat-containing protein 49 vs. Ensembl Xenopus
Match: ENSXETT00000029824.1 (EF-hand calcium binding domain 8 [Source:NCBI gene;Acc:100494912])

HSP 1 Score: 221.09 bits (562), Expect = 1.079e-58
Identity = 180/704 (25.57%), Postives = 316/704 (44.89%), Query Frame = 3
Query:  129 KLELKLNIKDLETLQEAFFMDGSHNRSQHFN--------------------GEEFVEALSLVLCKGTREEYSD-----LFDKIDITREGYVDWEKFASHMLLEFYEKDDRT--KSSSLPQWKELKTLSGPHKDVIQRIVLVRNLNR--YLTISKEGNVGLWGSDCKLQK---VAKTHTESC---RSRDLWVTDFAFLGNVNKVAVSFTSKEISFYD---MNVKLEFNCQVKLENLFRIPICMDYWHHPDN-NGEAIMAWGDTGGYINVILWSNISSSLFERVSSKASDKDENTXXXXXXXXXXXXXKTCTY-FSHKAHQDWVRKVSYIPNLECFVSCATNWNTSMVICWMEKYNPSNSTSSEMAGIPESRGFSRTSCFTVHQGINSFAYNENLNLIATAGVNFQVCLWNPYVISKPNGLLRGHMASVTDVQFNKARGHLISFSKDKILRIWDVQLQVCIQRYAGVFP-------KGQEMYSKMFYHEEKLRLFITFN--FGLTMLEMKPDVKDKISSHEKPLIGCLYNSLYNQVVTACQGGIIYCWMVDTGQRVKTITEICGPQAELTCITQDSTQTRLYTGATDGNVKIWDF-NGHCYNTLIVANGNPVDISQIVIL----KRCVLVFGFSKSITAFWTSSFKDHKVSPS-PWKGVQTHKDDILSGASIPPHA-VATGSYDGEIIIWNINSEQASRTMTQRSQ 2072
            +LE K  + DL  LQEAF    S  +  +                      G   ++    VLC     E  D     LF+++D + +GYVDW +F +++LL++ ++D R   + + L Q   ++  +   ++   RI+ + +      L++SK G +  W      QK   VA  + +S    R    WVTD   L N NK+A++ TS++I F+D   MN+  EF+    L  L  +P    YW++  +    +++ WG   G +NV+      + +FE+  S+     +          +    K  +Y      H + + K+ Y P  +  ++ + +  +S++I  + +                     +   + +++G+  F Y   LNL+ T G + +V LWN YV  +P  +L  H  ++ DV   +  G + SFSKD +L++WD+  Q C+      FP       + Q  +  +       RL + ++   G+  L      +    +H  P+   LY+S  + +VT  +   +  W V+TG +   +    G Q E+TC+  D  Q RL TGA +G +KIW+  NGH  + L      PV+ ++I  +    +   L  G+++ I  +      +  V  +  WKG Q H++DIL+    P    +AT S+DGEII+WN  +++    + Q  Q
Sbjct:   62 RLEEKFRLDDLRLLQEAFAKHNSDGKETNCKEESDDLRATRRRAKQEARPAGNMTLDEFRRVLCDLFGSECFDDDMELLFNEVDTSCDGYVDWGEFCTYLLLQYRKRDYRMIGRVTFLGQ-PVIRLCTRNKQEPTSRILAISSPPPMWLLSVSKTGVLTTWDLALHPQKSYEVAAEYPDSQAGKRRFKCWVTDAVHLPNANKIAIATTSRDIHFFDVSTMNLFEEFH----LFALNHVPTTFSYWYNKQSPESRSLLLWGGDNGAVNVLWLLQPQTGVFEKPFSQHPGPTK-----IYMQELKDHSKLLSYQVIPDVHPEAITKLIYCPEKQLIITSSGSAQSSLLIMDINQKG-------------------KVYTWKINKGVQCFDYCRALNLLVTGGFDHKVRLWNQYVTCRPIAVLPEHSMAILDVMIYQPLGQIFSFSKDSVLKVWDIPSQTCLHTLVLKFPCIQPGRIQEQGSFPFLLVPTNPSRLLVCYSDYIGILRLARAEPTEGTFFTHRAPVTCLLYSSFCHLIVTGSEDSTVAVWDVETGAKSLLLGNAHG-QEEVTCMALDKAQRRLITGARNGTIKIWNIQNGHNLHQL-----EPVEDAEITCIVASQENVFLTVGWNRKIVTYDIPKTNEVYVPANHSWKGGQLHQEDILTADFCPSLGLLATASFDGEIILWNAETQRLYLYLRQCPQ 730          

HSP 2 Score: 78.1814 bits (191), Expect = 8.555e-14
Identity = 47/157 (29.94%), Postives = 78/157 (49.68%), Query Frame = 3
Query: 2355 ISRLIYLESRKKIKHGGGANLISCGGNGIVRFW---NSAEGWLIGEFVAHENA--SNIIMNTDVSNQYLVTGDMDGYIRVWDILSYCQTESENQKIMSPPTLISQWQSHSDEISGISFCFKFSRTLIITSSADQSAALWELNGVLIGRFGQEHRWKL 2810
            + +L +L+ R   +    A ++     G +R+W   N  + W  G F A + A  S + + +D +N+ LV+GD  G ++VWDI +Y    +       PP L S W +H   +  +      S   I + S+D++A LW ++G  +G FGQ   WKL
Sbjct:  737 VDKLFFLQKRSAKRE---AAILVSSEAGTLRWWRVTNGGQEW--GSFYAQDEADCSVLGLASDKANRVLVSGDTLGLVQVWDISAYGLQAAAQTYTCRPPLLYS-WGAHDSAVVSVEHFLYDSEPFIASGSSDKTAKLWTVDGKQVGTFGQSKCWKL 887          
BLAST of WD repeat-containing protein 49 vs. Ensembl Xenopus
Match: ENSXETT00000025824.1 (WD repeat-containing protein 64-like [Source:NCBI gene;Acc:100498290])

HSP 1 Score: 200.29 bits (508), Expect = 5.218e-52
Identity = 157/585 (26.84%), Postives = 280/585 (47.86%), Query Frame = 3
Query:  435 PHKDVIQRIVLVRNLNRYLTISKEGNVGLWGSDCKLQK---VAKTHTESCRSRDLWVTDFAFLGNVNKVAVSFTSKEISFYDMNVKLEFNCQVKLENLFRIPICMDYWHHPDNNGEAIMAWGDTGGYINVILWSNISSSLFERVSSKASDKDENTXXXXXXXXXXXXXKTCTYFSHKAHQDWVRKVSYIPNLECFVSCATNWNTSMVICWME-------------KYNPSNSTSSEMAG-IPESRGFSRTSCFTVHQGINSFAYNENLNLIATAGVNFQVCLWNPYVISKPNGLLRGHMASVTDVQFNKARGHLISFSKDKILRIWDVQLQVCIQRYAGVFPKGQEMYSKMFYHEEKLRLFITFNFGLTMLEMK-----PDVKDKISSHEKPLIGCLYNSLYNQVVTACQGGIIYCWMVDTGQRVKTITEICGPQAELTCITQDSTQTRLYTGATDGNVKIWDFNG---HCYNTLIVANGNPVDISQIVIL------KRCVLVFGFSKSITAF---WTSSFKDHKVSPSPWKG--VQTHKDDILSGASIPPHAVATGSYDGEIIIWNINSEQASRTMTQRSQDEM 2081
            PH++ + +I  + + N  L + ++G + +W SD KL+K   +   + +  R    W+ D   +   NK+ V    +E+ FY+++   E  CQ+    L  +P+ + Y     +  E ++ +GD  G INVIL S+++ ++  R  +K    D+   +        G +K   +   K H DWV ++ Y+  ++  +S + +  T++VI  +E               + + S  S ++G +P  R  S  S F V +G+ +F + +  N++ T G++  V +WNPYV   P G LRGH + +T +Q       + S S D  + +WD++   C+        + +   +  F+  +   L+I  +   +ML+++     PDV     SH++P+  C YN    QVV+  +G +I  W + TG+ V  +    G  A +TC+  D+T +R+++ A DG++K WD +     C  TL  A  + +   Q          KR ++  G  K IT F     S+  +++     W       HK +IL  AS PP+ VA+ S DGEI IW++ S     ++    Q+E+
Sbjct:   32 PHREPLIQISPMPD-NSLLVVGQDGLISVWTSDLKLKKNRFILDENKQQNRKMK-WIADLTLMPQYNKLIVGTCDRELRFYELS-NFEPYCQII--GLETLPLHLGY--STRDTDEGVLYFGDEQGCINVILISSVAETI--RSWTKCQIIDDIPSVSMDIIESAGHVKLIRW---KVHNDWVTQIRYVNAIDSIISSSNDDYTALVIGCVEGTKNMQKRLKDLMDSSSTRSKRSMLSGNVPPKRNISDESLFKVKRGVKAFDFCKENNILVTGGLDRIVRIWNPYVPGWPTGSLRGHSSPITFLQIADENSKIYSVSTDCTVMVWDIEEHTCLINVISKASQIKGEIATCFFSSQFRALYIATD-SFSMLQLQHSITHPDVPS--VSHKEPVTCCQYNQYLEQVVSCSEGSVIKIWDLLTGKLVSEVRGAHG-SAAITCLALDNTGSRMFSVAKDGSLKQWDLSSTSVSCLTTLKEAVADSLTDGQYDCTYAWLHNKRFMISAGCGKQITIFPDQQDSAVVENQYPNHTWISNMRNKHKGEILCVASCPPNLVASSSSDGEIFIWDVTSGNMMCSLGIPKQEEL 600          

HSP 2 Score: 64.6994 bits (156), Expect = 1.097e-9
Identity = 47/153 (30.72%), Postives = 71/153 (46.41%), Query Frame = 3
Query: 2355 ISRLIYLESRKKIKHGGGANLISCGGNGIVRFWNSAEGW-LIGEF-VAHENASNIIMNTDVSNQYLVTGDMDGYIRVWDILSYCQTESENQKIMSPPTLISQWQSHSDEISGISFCFKFSRTLIITSSADQSAALWELNGVLIGRFGQEHRWK 2807
            I +LI+L SR        A L + G NG + FW+  +G  + G F  +H   +   M     +  L   D   Y+ +W+I  Y     E      PP LI  W++H  +I+ +    K+   L++TSS D +  LW + G  IG FGQ   W+
Sbjct:  611 IQKLIFLSSRDWKNEC--AVLAASGPNGQITFWHIFDGGKVFGSFPSSHYQTAVRDMAISEDDSTLCAADQLFYVYIWNISQYALHGPEAH----PPPLIHCWRAHQCDITRVVPVSKYK--LVVTSSVDCTVRLWSMKGEPIGTFGQSELWE 755          
BLAST of WD repeat-containing protein 49 vs. Ensembl Xenopus
Match: ENSXETT00000013991.1 (EF-hand calcium binding domain 8 [Source:NCBI gene;Acc:100494912])

HSP 1 Score: 191.815 bits (486), Expect = 3.634e-50
Identity = 146/555 (26.31%), Postives = 253/555 (45.59%), Query Frame = 3
Query:  489 LTISKEGNVGLWGSDCKLQK---VAKTHTESC---RSRDLWVTDFAFLGNVNKVAVSFTSKEISFYD---MNVKLEFNCQVKLENLFRIPICMDYWHHPDN-NGEAIMAWGDTGGYINVILWSNISSSLFERVSSKASDKDENTXXXXXXXXXXXXXKTCTY-FSHKAHQDWVRKVSYIPNLECFVSCATNWNTSMVICWMEKYNPSNSTSSEMAGIPESRGFSRTSCFTVHQGINSFAYNENLNLIATAGVNFQVCLWNPYVISKPNGLLRGHMASVTDVQFNKARGHLISFSKDKILRIWDVQLQVCIQRYAGVFP-------KGQEMYSKMFYHEEKLRLFITFN--FGLTMLEMKPDVKDKISSHEKPLIGCLYNSLYNQVVTACQGGIIYCWMVDTGQRVKTITEICGPQAELTCITQDSTQTRLYTGATDGNVKIWDF-NGHCYNTLIVANGNPVDISQIVIL----KRCVLVFGFSKSITAFWTSSFKDHKVSPS-PWKGVQTHKDDILSGASIPPHA-VATGSYDGEIIIWNINSEQASRTMTQRSQ 2072
            L++SK G +  W      QK   VA  + +S    R    WVTD   L N NK+A++ TS++I F+D   MN+  EF+    L  L  +P    YW++  +    +++ WG   G +NV+      + +FE+  S+     +          +    K  +Y      H + + K+ Y P  +  ++ + +  +S++I  + +                     +   + +++G+  F Y   LNL+ T G + +V LWN YV  +P  +L  H  ++ DV   +  G + SFSKD +L++WD+  Q C+      FP       + Q  +  +       RL + ++   G+  L      +    +H  P+   LY+S  + +VT  +   +  W V+TG +   +    G Q E+TC+  D  Q RL TGA +G +KIW+  NGH  + L      PV+ ++I  +    +   L  G+++ I  +      +  V  +  WKG Q H++DIL+    P    +AT S+DGEII+WN  +++    + Q  Q
Sbjct:    4 LSVSKTGVLTTWDLALHPQKSYEVAAEYPDSQAGKRRFKCWVTDAVHLPNANKIAIATTSRDIHFFDVSTMNLFEEFH----LFALNHVPTTFSYWYNKQSPESRSLLLWGGDNGAVNVLWLLQPQTGVFEKPFSQHPGPTK-----IYMQELKDHSKLLSYQVIPDVHPEAITKLIYCPEKQLIITSSGSAQSSLLIMDINQKG-------------------KVYTWKINKGVQCFDYCRALNLLVTGGFDHKVRLWNQYVTCRPIAVLPEHSMAILDVMIYQPLGQIFSFSKDSVLKVWDIPSQTCLHTLVLKFPCIQPGRIQEQGSFPFLLVPTNPSRLLVCYSDYIGILRLARAEPTEGTFFTHRAPVTCLLYSSFCHLIVTGSEDSTVAVWDVETGAKSLLLGNAHG-QEEVTCMALDKAQRRLITGARNGTIKIWNIQNGHNLHQL-----EPVEDAEITCIVASQENVFLTVGWNRKIVTYDIPKTNEVYVPANHSWKGGQLHQEDILTADFCPSLGLLATASFDGEIILWNAETQRLYLYLRQCPQ 524          

HSP 2 Score: 77.411 bits (189), Expect = 1.041e-13
Identity = 47/157 (29.94%), Postives = 78/157 (49.68%), Query Frame = 3
Query: 2355 ISRLIYLESRKKIKHGGGANLISCGGNGIVRFW---NSAEGWLIGEFVAHENA--SNIIMNTDVSNQYLVTGDMDGYIRVWDILSYCQTESENQKIMSPPTLISQWQSHSDEISGISFCFKFSRTLIITSSADQSAALWELNGVLIGRFGQEHRWKL 2810
            + +L +L+ R   +    A ++     G +R+W   N  + W  G F A + A  S + + +D +N+ LV+GD  G ++VWDI +Y    +       PP L S W +H   +  +      S   I + S+D++A LW ++G  +G FGQ   WKL
Sbjct:  531 VDKLFFLQKRSAKRE---AAILVSSEAGTLRWWRVTNGGQEW--GSFYAQDEADCSVLGLASDKANRVLVSGDTLGLVQVWDISAYGLQAAAQTYTCRPPLLYS-WGAHDSAVVSVEHFLYDSEPFIASGSSDKTAKLWTVDGKQVGTFGQSKCWKL 681          
BLAST of WD repeat-containing protein 49 vs. Ensembl Mouse
Match: Wdr49 (WD repeat domain 49 [Source:MGI Symbol;Acc:MGI:3645287])

HSP 1 Score: 468.774 bits (1205), Expect = 5.739e-149
Identity = 274/751 (36.48%), Postives = 408/751 (54.33%), Query Frame = 3
Query: 1110 ESRGFSRTSCFTVHQGINSFAYNENLNLIATAGVNFQVCLWNPYVISKPNGLLRGHMASVTDVQFNKARGHLISFSKDKILRIWDVQLQVCIQRYAGVFPKGQEMYSKMFYHEEKLRLFITFNFGLTMLEMKPDVKDKISSHEKPLIGCLYNSLYNQVVTACQGGIIYCWMVDTGQRVKTITEICGPQAELTCITQDSTQTRLYTGATDGNVKIWDFNGHCYNTLIVANGNPVDISQIVILKRCVLVFGFSKSITAFWTSSFKDHKVSPSPWKGVQTHKDDILSGASIPPHAVATGSYDGEIIIWNINSEQASRTMTQRSQDEMKEVKKLAEQTIVRIKMAANAELKRAASNSIQQETDDKLDFIKAEIQNSIANRQXXXXXXXXXXXXXXXXXXXXDTVSDMQVQYKKMDVMFNISRLIYLESRKKIKHGGGANLISCGGNGIVRFWNSAEGWLIGEFVAHENASNIIMNTDVSNQYLVTGDMDGYIRVWDILSYCQTESENQKIMSPPTLISQWQSHSDEISGISFCFKFSRTLIITSSADQSAALWELNGVLIGRFGQEHRWKLGSXXXXXXXXXXXXHEDEVVKQEEDKYKVDPNWYPDPEAIQNPSGYRINTWKD----TNLGKDYQELRVRKRERIQPSSIPDLPY--LYGEKIGRPTFGPFYSLNISSFEEIEDIEQPEFMEYPEKFFNE-TEEFLTKTARVPLLNETLKAVFDERSLLPEYILEFEHKFRNRFQRHLSEAKVK 3341
            +S+   + + F + QGI++F Y+  LNLIATAG+N +VCLWNPYV+SKP G+L GH ASV  VQF   R  L SFS+DK+LR+WD+Q Q+ IQR    FPK Q+      + E   RLFI+FN  L +L +K +   ++ SH K +   LYNSL  QV+++  G  +  WM++TGQ++K     C   AE++ +  D+ +TRL TG+TDG VK+WDFNG+C+ TL V     VDISQI++LK+ +LV G+ +++  F   +F    +    WKG   H+DDIL  A  PP  + TGSYDGEI++WN N+E A   +    Q ++  +  +  Q   ++    + E    A  + Q   + K+D    E  N++                                            RL +LE+RK     GGANL+SCG +G VRFW++ +  L+ EF+AH    +IIM+TD  NQYL TGD DG++++W+I  YC T S   KI  PP L+   Q H D IS +  C    R LII+SSAD S  +  L+      FGQ   W + +    P             K +E++ KV+P  +   E   + + + + T +D    T+L  +     ++ + R   +S+    Y   YGE I   T   F SL + + +E+ ++++P F+  P+K+F E  EE +++   +PLL+ETLKAVFDE+SL P+ +L  E + ++  Q    E K+K
Sbjct:   14 KSKKLLKMTSFNIAQGIHAFDYHSRLNLIATAGINNKVCLWNPYVLSKPVGVLWGHSASVIAVQFFAERKQLFSFSRDKVLRLWDIQHQLSIQRITCSFPKSQDFRCLFQFDETHGRLFISFNNQLALLAIKNEASKRVKSHLKAVSCVLYNSLLKQVISSDVGSTVSFWMIETGQKIKQFAG-CHGNAEISTMALDANKTRLLTGSTDGTVKVWDFNGYCHYTLNVGQDGVVDISQILVLKKTILVVGWERALIVFRPQNFNQFFIQSEEWKGGVHHQDDILCAAFSPPQTLVTGSYDGEIVLWNNNTENAHHALHPGYQRQLTSMVDVEAQ---KLNSRRSCESHGVADQATQAARNVKID---TEGNNAVM-------------------------------------------RLCFLEARKTKAATGGANLVSCGASGYVRFWDTFKKVLLAEFLAHAGVGSIIMSTDKLNQYLATGDSDGWLKIWNIEEYC-TNSTESKITQPPPLLRSSQPHEDRISSLEMCESCGRLLIISSSADCSVCVTGLSSAPALIFGQASHWNIENHFSLPERDTNLIES----KNQEERMKVNP-LFSKEELCLDSTEHSLLTEEDEDNSTHLSTEEMNFSLKYKRR---NSLKKKAYKPCYGEIIQTST-STFGSLCLRTLKELPEVKKPAFLLDPDKYFKEGPEEDVSQIPELPLLSETLKAVFDEKSLFPKELLYRERQDKSLCQETNGEMKIK 704          
BLAST of WD repeat-containing protein 49 vs. Ensembl Mouse
Match: Wdr49 (WD repeat domain 49 [Source:MGI Symbol;Acc:MGI:3645287])

HSP 1 Score: 397.897 bits (1021), Expect = 5.692e-125
Identity = 210/498 (42.17%), Postives = 310/498 (62.25%), Query Frame = 3
Query:   96 SKESHTPLTENKLELKLNIKDLETLQEAFFMDGSHNRSQH--FNGEEFVEALSLVLCKGTREEYSDLFDKIDITREGYVDWEKFASHMLLEFYEKDDRTKSSSLPQWKELKTLSGPHKDVIQRIVLVRNLNRYLTISKEGNVGLWGSDCKLQKVAKTHTESCRSRDLWVTDFAFLGNVNKVAVSFTSKEISFYDMNVKLEFNCQVKLENLFRIPICMDYWHHPDNNGEAIMAWGDTGGYINVILWSNISSSLFERVSSKASDKDENTXXXXXXXXXXXXXKTCTYFSHKAHQ-DWVRKVSYIPNLECFVSCATNWNTSMVICWMEKYNPSNSTSSEMAGIPESRGFSRTSCFTVHQGINSFAYNENLNLIATAGVNFQVCLWNPYVISKPNGLLRGHMASVTDVQFNKARGHLISFSKDKILRIWDVQLQVCIQRYAGVFPKGQEMYSKMFYHEEKLRLFITFNFGLTMLEMKPDVKDKISSHEKPLIGCLYNSLYNQ 1580
            S++  T L ENKL    +++D   +Q+ F    S + SQ      EEFV+ ++  +  GT+EEY +LFDK+D+ R+G++DW+K  S +LL  YE+D+R K++ +PQWK+L+ L G HKD IQ++V +++ +RYLT+SKEG +G+WG + KLQ+     +++ + + LWVT    L NVNK+AV+FTS+EI FYD+  K EF CQ KL+ L   PICMDYW+ P +  ++I+++GD  G +  + ++    SLFER  + A D +E T+ I   +++ G  K C    H  H  DWVR+V+Y  +L+ F+S   +   ++V+ W EK                S+   + + F + QGI++F Y+  LNLIATAG+N +VCLWNPYV+SKP G+L GH ASV  VQF   R  L SFS+DK+LR+WD+Q Q+ IQR    FPK Q+      + E   RLFI+FN  L +L +K +   ++ SH K +   LYNSL  Q
Sbjct:   38 SEDYGTDLFENKL----SVEDFVKIQQVF---ESQDPSQTICMPREEFVQKMAETVGWGTKEEYGELFDKVDVARDGFIDWDKLTSFILLLLYERDERAKATVVPQWKDLEFLPGKHKDTIQKVVFLKSSSRYLTVSKEGLLGIWGENLKLQESLPITSDAIKLKHLWVTSLVSLENVNKIAVAFTSREICFYDLLSKEEFPCQYKLQGLQGAPICMDYWYDPIDPKDSILSFGDITGKVQAVAFTAAMISLFER-PANACDNEEATMTIDWAELVSGCHKCCHVLQHTLHHGDWVRQVTYNASLDAFISSTMSGINTVVLAWREK----------------SKKLLKMTSFNIAQGIHAFDYHSRLNLIATAGINNKVCLWNPYVLSKPVGVLWGHSASVIAVQFFAERKQLFSFSRDKVLRLWDIQHQLSIQRITCSFPKSQDFRCLFQFDETHGRLFISFNNQLALLAIKNEASKRVKSHLKAVSCVLYNSLLKQ 511          
BLAST of WD repeat-containing protein 49 vs. Ensembl Mouse
Match: Wdr49 (WD repeat domain 49 [Source:MGI Symbol;Acc:MGI:3645287])

HSP 1 Score: 391.734 bits (1005), Expect = 1.280e-123
Identity = 197/453 (43.49%), Postives = 289/453 (63.80%), Query Frame = 3
Query:  225 EEFVEALSLVLCKGTREEYSDLFDKIDITREGYVDWEKFASHMLLEFYEKDDRTKSSSLPQWKELKTLSGPHKDVIQRIVLVRNLNRYLTISKEGNVGLWGSDCKLQKVAKTHTESCRSRDLWVTDFAFLGNVNKVAVSFTSKEISFYDMNVKLEFNCQVKLENLFRIPICMDYWHHPDNNGEAIMAWGDTGGYINVILWSNISSSLFERVSSKASDKDENTXXXXXXXXXXXXXKTCTYFSHKAHQ-DWVRKVSYIPNLECFVSCATNWNTSMVICWMEKYNPSNSTSSEMAGIPESRGFSRTSCFTVHQGINSFAYNENLNLIATAGVNFQVCLWNPYVISKPNGLLRGHMASVTDVQFNKARGHLISFSKDKILRIWDVQLQVCIQRYAGVFPKGQEMYSKMFYHEEKLRLFITFNFGLTMLEMKPDVKDKISSHEKPLIGCLYNSLYNQ 1580
            EEFV+ ++  +  GT+EEY +LFDK+D+ R+G++DW+K  S +LL  YE+D+R K++ +PQWK+L+ L G HKD IQ++V +++ +RYLT+SKEG +G+WG + KLQ+     +++ + + LWVT    L NVNK+AV+FTS+EI FYD+  K EF CQ KL+ L   PICMDYW+ P +  ++I+++GD  G +  + ++    SLFER  + A D +E T+ I   +++ G  K C    H  H  DWVR+V+Y  +L+ F+S   +   ++V+ W EK                S+   + + F + QGI++F Y+  LNLIATAG+N +VCLWNPYV+SKP G+L GH ASV  VQF   R  L SFS+DK+LR+WD+Q Q+ IQR    FPK Q+      + E   RLFI+FN  L +L +K +   ++ SH K +   LYNSL  Q
Sbjct:   13 EEFVQKMAETVGWGTKEEYGELFDKVDVARDGFIDWDKLTSFILLLLYERDERAKATVVPQWKDLEFLPGKHKDTIQKVVFLKSSSRYLTVSKEGLLGIWGENLKLQESLPITSDAIKLKHLWVTSLVSLENVNKIAVAFTSREICFYDLLSKEEFPCQYKLQGLQGAPICMDYWYDPIDPKDSILSFGDITGKVQAVAFTAAMISLFER-PANACDNEEATMTIDWAELVSGCHKCCHVLQHTLHHGDWVRQVTYNASLDAFISSTMSGINTVVLAWREK----------------SKKLLKMTSFNIAQGIHAFDYHSRLNLIATAGINNKVCLWNPYVLSKPVGVLWGHSASVIAVQFFAERKQLFSFSRDKVLRLWDIQHQLSIQRITCSFPKSQDFRCLFQFDETHGRLFISFNNQLALLAIKNEASKRVKSHLKAVSCVLYNSLLKQ 448          
BLAST of WD repeat-containing protein 49 vs. Ensembl Mouse
Match: Efcab8 (EF-hand calcium binding domain 8 [Source:MGI Symbol;Acc:MGI:3644206])

HSP 1 Score: 294.278 bits (752), Expect = 3.255e-81
Identity = 244/974 (25.05%), Postives = 445/974 (45.69%), Query Frame = 3
Query:  126 NKLELKLNIKDLETLQEAFFMDGSHNRSQHFNGEEFVEALSLVLCKGTREEYSDLFDKIDITREGYVDWEKFASHMLLEFYEKDDRTKSSSLPQWKELKTLSGPH--KDVIQRIVLVR---NLNRYLTISKEGNVGLWGSD-CKLQKVAKTHTESCRSRDLWVTDFAFLGNVNKVAVSFTSKEISFYDMNVKLEFNCQVKLENLFRIPIC---MDYWHHPDNNGEAIMAWGDTGGYINVILWSNISSSLF-ERVSSKASDKDENTXXXXXXXXXXXXXKTCTYFSHKAHQDWVRKVSYIPNLECFVSCATNWNTSMVICWMEKYNPSNSTSSEMAGIPESRGFSRTSCFTVHQGINSFAYNENLNLIATAGVNFQVCLWNPYVISKPNGLLRGHMASVTDVQFNKARGH-LISFSKDKILRIWDVQLQVCIQRYAG-VFPKGQEMYSKMFYHEEKLRLFITFNFGLT--MLEMKPDVK-DKISSHEKPLIGCLYNSLYNQVVTACQGGIIYCWMVDTGQRVKTITEICGPQAELTCITQDSTQTRLYTGATDGNVKIWDFN-GHCYNTLIVANGNPVDISQIVILKRCVLVFGFSKSITAFWTSSFKDHKVSPSPWKGVQTHKDDILSGASIPPHAVATGSYDGEIIIWNINSEQASRTMTQRSQDEMKEVKKLAEQTIVRIKMAANAELK---------RAASNSIQQETDDKLDFIK----AEIQNSIANRQXXXXXXXXXXXXXXXXXXXXDTVSDMQVQYKKMDV--------MFNISRLIYLESRKKIKHGGGANLISCGGNGIVRFWN-SAEGWLIGEF-VAHENASNII--MNTDVSNQYLVTGDMDGYIRVWDILSYC---------------QTESENQ------------------------------KIMSPPTLISQWQSHSDEISGISFCFKFSRTLIITSSADQSAALWELNGVLIGRFG 2789
            N+ + + +   L  LQ+ F  +   N +     E F+  +  VL   + E    LF K+D    G+V W+K+  +M+ EF  K++  KS    ++    T+   H   +V++   L +    + R+LT++K+G +  W      L+    + ++    + +WV D A+L N++ +AV+ T  +I F+D+     + C ++   +  +  C   MDYW    +  +A+  +GDT G   + +  N++  LF  ++  +AS  D    +     +   +    ++     H +W ++V YIP L    SC+    +S+V+  +    P                  R S   + +GI  F Y  + N +AT G +  + LWNP V  KP  L++GH  SVT +  N      LIS S+DK +R+WD+Q  VC+Q + G +FP G    +  +++     +  T+N G+    LE +  +K  ++++H  PL   LY+ ++ QVV+ C  G++  W + TG++   I      ++ELT +  D ++  L TG  DG +++W++N G C  T    N + V+IS IV + +     G+SK IT F   +F+    + S +     H +DILS        + T SY+G+I+ WN+++ +   +          E KK+ ++ I   K +   + +         ++A ++ ++        +K    AE Q ++A ++          S+     S      D   Q +K D+          ++ ++++L++R ++ H   A L+S   +G +  W+    G L+G+F V +E   +++  M TD ++  L+TGD  G I++WDI  YC                 ++EN+                               ++ PP LI+ W SH D ++ I +   F   L++++  D+    W L+G  IG FG
Sbjct:  102 NQRDQQFSDMHLADLQKVFEKEADENGA--LKKEGFIRIMKGVLSSMSEEMLELLFLKVDSDCNGFVTWQKYVDYMMREFQGKEEMRKSQYRLRFHLPMTVIPLHHGSEVVKVACLTKRFKKMGRFLTVTKDGILQFWSETFSMLESFHLSQSKQYGHQQMWVIDVAYLHNMSLIAVASTELKIEFFDIG---GYKC-IRAFTVIDLDSCVMVMDYW---TDCHKAVFCYGDTKGNATIFISDNVAGGLFNPQILPRASKWDHWFTVSLKKLLNEKAPLYRSFRMKGLHPNWCQQVKYIPQLNVVASCSAVEKSSLVLIILPGKEPEKP---------------RLSSLNLRKGILCFDYCPDRNFLATGGYDPHIRLWNPLVSKKPVWLMKGHQTSVTHLLVNSRNASILISISRDKNIRVWDLQDYVCLQSFCGKLFPLGNCPITSTYFYRSSTLICSTYNIGILRGYLESQGPLKTGRMTTHNTPLCAVLYSKIFKQVVSGCLQGLVSVWDISTGKKRMEIPVSGIQESELTAMALDQSERCLLTGLRDGTMQMWNYNTGECLMTF--PNPDRVEISGIVHMNKVFYTTGWSKRITNF---TFQKITQALSCYHWQSFHTEDILSMDKYQNQFLGTSSYNGDIVFWNVSTSKPILSFNASKSPLPLEPKKVRDKEICIPKTSIRLDYEDQKWAHRPWKSAISTGKRRLMSAPPVMKHWKDAEQQRNMA-QEKHFRSHKPGLSKMLVNKSGNKLAFDKDTQKRKGDLWRKLLLQSSVSVEKILFLQTRPRLPH--TAALLSSSIDGFIYAWSIHGNGGLLGKFSVDNEVGESVVGAMATDENDWILLTGDSKGNIKIWDIKDYCYFIDQQPLQSSGNSLSVDTENKFRLLIPKQLQVCSEHHLPQEEKEVVEGQTFSLVPPPLLIT-WNSHLDSVTDILYVNSFQ--LVVSAGQDRDVKAWRLSGDAIGTFG 1040          
BLAST of WD repeat-containing protein 49 vs. Ensembl Mouse
Match: Wdr95 (WD40 repeat domain 95 [Source:MGI Symbol;Acc:MGI:1923042])

HSP 1 Score: 176.022 bits (445), Expect = 1.036e-44
Identity = 116/404 (28.71%), Postives = 197/404 (48.76%), Query Frame = 3
Query:  942 YFSHKAHQDWVRKVSYIPNLECFVSCATNWNTSMVICWM-----------------EKYNPSNST--------SSEMAGIPESRGFSRTSCFTVHQGINSFAYNENLNLIATAGVNFQVCLWNPYVISKPNGLLRGHMASVTDVQFNKARGHLISFSKDKILRIWDVQLQVCI----QRYAGVFPKGQEMYSKMFYHEEKLRLFITFNFGLTMLEMKPDVKDK-ISSHEKPLIGCLYNSLYNQVVTACQGGIIYCWMVDTGQRVKTITEICGPQAELTCITQDSTQTRLYTGATDGNVKIWDF-NGHCYNTLIVANGNPVDISQIVILK----RCVLVFGFSKSITAFWTSSFKDHKV-SPSP-WKGV--QTHKDDILSGASIPPHAVATGSYDGEIIIWNINS 2036
            Y   K H D+V +++Y  +++  +S + +  T++VI  +                 EK N   +         SS    +P+ +     + F VH+G+ +F++    NL+ T G++  + +WNPY+  KP G+LRGH A V  V        + S S D  +++WD++   C      + +G+  KG E+ + ++    +     T       L++    +   + SH++P++ C YN  +  VV+ C+  ++  W  +TG++V       G  A +TC+T DS+  RL TG  DG +KIW + NGHC +TL   + N  ++     ++    RCV+  G+ + I  ++      H    P P W+      HK+DIL  A  PP  +AT SYDGEII+WN+ S
Sbjct:   48 YVRWKVHGDFVSQLNYYESMKAVISSSNHEPTALVIGSLLNRLEHGGFTVGATDIKEKLNEIRNVGKNVKMGNSSACLALPQRQAECNRTVFRVHKGVKAFSFCRRKNLLVTGGLDRIIRVWNPYLPGKPTGVLRGHRAPVMYVHVAFEENKVFSMSADNTVKVWDLETHGCCCTISSKASGI--KG-ELTACLYLPGPRALCVATGTLAFLHLKVGSVPESHLVRSHQEPVVCCRYNPAFRHVVSCCEASVVKVWDFETGRQVSEFIGTHG-NAGITCLTFDSSGRRLVTGGRDGCLKIWSYNNGHCLHTL-QHDENQSEVCDCTYMEVNRNRCVIAVGWDRRINVYFDIPRDFHHFRKPQPHWQDDLNHGHKEDILCVAQCPPFLLATSSYDGEIIVWNVIS 446          

HSP 2 Score: 68.5514 bits (166), Expect = 4.989e-11
Identity = 52/174 (29.89%), Postives = 83/174 (47.70%), Query Frame = 3
Query: 2301 DTVSDMQVQYKKMDVMFNISRLIYLESRKKIKHGGGANLISCGGNGIVRFWNSAEG-WLIGEFV-AHENA--SNIIMNTDVSNQYLVTGDMDGYIRVWDILSYCQTESENQKIMSPPTLISQWQSHSDEISGISFCFKFSRTLIITSSADQSAALWELNGVLIGRFGQEHRWKL 2810
            +T S M  Q  +     ++S+L +L++R        A LIS G  G V FW    G  L+  F  + E A  S I++ +  +  YL   D  G+I V+DI  Y    +E Q     P  ++ W++H   ++ +      S  ++++SS D +  LW  +G  IG FGQ H W +
Sbjct:  454 NTPSPMDGQDHREGPDRSVSQLAFLKTRLTKLDSASAALISNGPGGSVCFWKLFSGSGLVANFTPSREKAQVSGIVVTSGDTLAYLA--DQHGFIHVYDIQEYGLQGTELQA----PNTVTSWRAHVSMVTSLELIEGGS--IVLSSSLDCTVRLWSQDGAYIGTFGQNHPWDV 619          
BLAST of WD repeat-containing protein 49 vs. UniProt/SwissProt
Match: sp|Q8IV35|WDR49_HUMAN (WD repeat-containing protein 49 OS=Homo sapiens OX=9606 GN=WDR49 PE=2 SV=1)

HSP 1 Score: 318.546 bits (815), Expect = 7.065e-93
Identity = 157/330 (47.58%), Postives = 213/330 (64.55%), Query Frame = 3
Query: 1095 MAGIPESRGFSRTSCFTVHQGINSFAYNENLNLIATAGVNFQVCLWNPYVISKPNGLLRGHMASVTDVQFNKARGHLISFSKDKILRIWDVQLQVCIQRYAGVFPKGQEMYSKMFYHEEKLRLFITFNFGLTMLEMKPDVKDKISSHEKPLIGCLYNSLYNQVVTACQGGIIYCWMVDTGQRVKTITEICGPQAELTCITQDSTQTRLYTGATDGNVKIWDFNGHCYNTLIVANGNPVDISQIVILKRCVLVFGFSKSITAFWTSSFKDHKVSPSPWKGVQTHKDDILSGASIPPHAVATGSYDGEIIIWNINSEQASRTMTQRSQDEMK 2084
            MA   +S+     + F + QGI++F Y+  LNLIATAG+N +VCLWNPYV+SKP G+L GH ASV  VQF   R  L SFSKDK+LR+WD+Q Q+ IQR A  FPK Q+      + E   RLFI+FN  L +L MK +   ++ SHEK +   LYNS+  QV+++  G  +  WM+DTGQ++K  T  C   AE++ +  D+ +TRL TG+TDG VKIWDFNG+C++TL V     VDISQI+ILK+ +LV G+ ++IT F   +F    + P  WKG   H DDIL  A +PP  + TGSYDGEI++WN ++E A   +    Q  +K
Sbjct:    1 MAWREKSKKRLNMTSFNIAQGIHAFDYHSRLNLIATAGINNKVCLWNPYVVSKPVGVLWGHSASVIAVQFFVERKQLFSFSKDKVLRLWDIQHQLSIQRIACSFPKSQDFRCLFHFDEAHGRLFISFNNQLALLAMKSEASKRVKSHEKAVTCVLYNSILKQVISSDTGSTVSFWMIDTGQKIKQFTG-CHGNAEISTMALDANETRLLTGSTDGTVKIWDFNGYCHHTLNVGQDGAVDISQILILKKKILVTGWERAITVFRPQNFNQFFIQPEEWKGGIQHHDDILCAAFLPPQTLVTGSYDGEIVLWNNSTENAHHVLHPDYQRLLK 329          

HSP 2 Score: 197.208 bits (500), Expect = 3.805e-51
Identity = 123/333 (36.94%), Postives = 178/333 (53.45%), Query Frame = 3
Query: 2355 ISRLIYLESRKKIKHGGGANLISCGGNGIVRFWNSAEGWLIGEFVAHENASNIIMNTDVSNQYLVTGDMDGYIRVWDILSYCQTESENQKIMSPPTLISQWQSHSDEISGISFCFKFSRTLIITSSADQSAALWELNGVLIGRFGQEHRWKLGSXXXXXXXXXXXXHEDEVVKQEEDKYKVDPNWYPDPEAIQNP-----SGYRINTWKDTNLGKDYQELRVRKRERIQPSSIPDLPYLYGEKIGRPTFGPFYSLNISSFEEIEDIEQPEFMEYPEKFF-NETEEFLTKTARVPLLNETLKAVFDERSLLPEYILEFEHKFRNRFQRHLSEAK 3335
            + RL +L++RK     GGANL+SCGG+G VRFW+  +  L+ EF+AH    +IIM+TD  N+YL TGD+DG++++W+I  YC   S+N KI   PTLI  +Q H D IS +  C    + LII+SSAD S  +  +    +  FGQ   W + + +  P        E E+ K+     K +    P   ++ N      S Y +   +D NL   Y+E     +E  +P         YGE I + +F  F SLNI + EE+ ++ +P F+  PEK+F  E EE   +    P L +TLKAVFDE++L P+ IL  E K +   Q    E K
Sbjct:  372 VMRLCFLKARKNTAVTGGANLVSCGGSGYVRFWDIYKKQLLAEFLAHSGVGSIIMSTDKMNRYLTTGDLDGWLKIWNIEEYCLNSSKN-KITKAPTLIRSFQPHEDRISSLEMCEPGGQLLIISSSADCSICVTGVCNAPVWIFGQAKHWHIENCLFLPKRDTNLV-ESEIQKEISLFSKEESCLDPTEHSLLNKKNKDDSTYNVRPSEDINLDIKYKERSTCMKETQKP--------YYGEVI-KKSFSTFRSLNIGALEELPEVNKPAFLLDPEKYFRKEPEEERPQILEAPSLFKTLKAVFDEKNLFPKEILHHERKAKQLCQEKSCEVK 693          
BLAST of WD repeat-containing protein 49 vs. UniProt/SwissProt
Match: sp|Q17I16|WDY_AEDAE (WD repeat-containing protein on Y chromosome OS=Aedes aegypti OX=7159 GN=WDY PE=4 SV=1)

HSP 1 Score: 180.259 bits (456), Expect = 1.504e-44
Identity = 215/948 (22.68%), Postives = 386/948 (40.72%), Query Frame = 3
Query:  132 LELKLNIKDLETLQEAFFMDGSHNRSQHFNGEEFVEALSLVLCKGTREEYSDLFDKIDITREGYVDWEKFASHMLLEFYEKDDRT--KSSSLPQWKELKTLSGPHKDVIQRIVLVRNLNR----------YLTISKEGNVGLWGSDCKLQKVAKTHTESCRSRDLWVTDFAFLGNVNKVAVSFTSKEISFYDMNVKLEFNCQVKLENLFRIPICMD--YWHH-PDNNGEAIMAWGDTGGYINVILWSNISSSLFERVSSKASDKDENTXXXXXXXXXXXXXKTCTYFSHKAHQDWVRKVSYIPNLECFVSCATNWNTSMVICWMEKYNPSNSTSSEMAGIPESRGFSRTSCFTVHQGINSFAYNENLNLIATAGVNFQVCLWNPYVISKPNGLLRGHMASVTDVQFNKARGHLISFSKDKILRIWDVQLQVCIQRYAGVFPKGQEMYSKMFYHEEKLRLFITFNFGLTMLEMKPDVKDKIS---SHEKPLIGCLYNSLYNQVVTACQGGIIYCWMVDTGQRVKTI-----TEICG---PQAELTCITQDSTQTRLYTGATDGNVKIWDFNGHCYNTLIVANGNPVDISQIVILKRCVLVFGFSKSITAFWTSSFKDHKVSPSPWKGVQTHKDDILSGA--SIPPHAVATGSYDGEIIIWNINSEQASRTMTQRSQDEMKEVKKLAEQTIVRIKMAANAELKRAASNSIQQETDDKLDFIKAEIQNSIANRQXXXXXXXXXXXXXXXXXXXXDTVSDMQVQYKKMDVMFNISRLIYLESRKKIKHGGGANLISCGGNGIVRFWNSAEGWLIGEFVAHENASN--IIMNTDVSNQYLVTGDMDGYIRVWDILSYCQTESENQKI---------------MSP------------PTLISQWQSHSDEISGISFCFKFSRTLIITSSADQSAALWELNGVLIGRFGQEHRW 2804
            L   L+  D+E L   F     + R Q    E   E   L   +   EE+  LF KI+  ++ Y  W++  S+++L F   D     +S  LP  +++    G     + +I     ++           ++T ++E  +  W  D K  K  K  +   +     V D A L + N   V+    E+ FYD+ +   F  +  +    RIP  ++  Y+H  PD   + I+  GD  G++ +I +   +   F+  ++ A  +    +             TC  +  +   D VR+V +I +   FV+C+ N         +  ++  N     +  I  +R   R + F V +G+  FA++   + + T G + Q+ LW+     KP  +L GH ++V  +        L S  + KI++IWDV  +  IQ Y+       +      Y+ E  R  +     +  +   P +  +++   SH +P+   L+N L+  +V+      I  W   TG R  TI     TE+      + ++T    D     + TGA +G +KIW+FN     + + + G+  +++ +   +  +L  G++  I  F   S      S   W+  + H DDIL  +     P A+A+ SY GEII+W + + QA +       D  K           R K+  N + KR     I Q T  +      + Q     R+               T       +++  Q         I  L++LE+R       G  L S     I+ F +  +G  +G F A   A +  I+M TD  N++L TG   GYI++W + +Y     +  K+               + P            P L+S +Q+H   ++ +   +  +  L++++S+D++  +W ++G  +G  G   +W
Sbjct:   15 LHRYLSQNDVEHLYRIF-----NKRKQLLPEELRTELTDLTGVEFQDEEFQTLFMKINANKDEYCQWDELVSYLILGFQNDDPLAVQESLDLPISQDMGMKLGRQTYPVTKIQYAPLVSYDGTVNWSQGFWVTSTREAVINFWKRDWKHLKTGKAFSVDLKRIKTMVLDTAILPDQNYFCVACLECELRFYDI-IASGFTLKTIIN---RIPNAINSLYYHFSPDTRSKMIL--GDYVGHVRMIEFFPENKEPFKFDAATAITR----MAFCDLVGGLCPQMTCVDYG-RLLPDIVRQVEFIESRNSFVACSENDP-------LVPHHMRNKLQVSLV-IQHTRKLDRRTKFKVFKGVTCFAFDSIKDFLVTGGPDGQLRLWDSRRSDKPTEILAGHNSAVVFMFLQDESLKLYSMDQKKIVKIWDVPNRTLIQTYSQFSSSMFKTVPACAYYSELNRELVVGANKVLSVSCCPKIALEVTDGESHTQPISVLLHNPLFKVIVSCGLDSFIIVWDY-TGNRKLTIIQDAHTEVIHGILEKVQITAACFDPKLQLMVTGARNGELKIWNFNSGSLMSCM-SIGSECEVTAVFWERTGILAMGWNHVIVEFPVGSTGIDFPSGVEWQ--KLHSDDILCASINRTEPKALASCSYSGEIILWMLETGQAYKRF-----DAAKP----------RQKIPVNFKKKR-----IPQPTRRQTRLSIFQPQEHWRQRR--------------LTRIVMPATAELLRQ-------LTIHNLLFLEAR-PFHPDYGTLLASLDTGRILVFSHHPDGGYMGAFSAVHMAGDRVIMMTTDSDNRFLFTGTYLGYIKIWLLENYFVPSGKQPKVNRAALRLQFPFLMDDVVPGRAKRSVANQPMPMLLSSYQAHRTCVTDL--VYMHASQLLVSASSDRTIRIWTISGRYVGLLGSPVKW 890          
BLAST of WD repeat-containing protein 49 vs. UniProt/SwissProt
Match: sp|B4F7L9|WDY_DROME (WD repeat-containing protein on Y chromosome OS=Drosophila melanogaster OX=7227 GN=WDY PE=2 SV=2)

HSP 1 Score: 160.229 bits (404), Expect = 2.373e-38
Identity = 142/607 (23.39%), Postives = 256/607 (42.17%), Query Frame = 3
Query: 1122 FSRTSCFTVHQGINSFAYNENLNLIATAGVNFQVCLWNPYVISKPNGLLRGHMASVTDVQFNKARGHLISFSKDKILRIWDVQLQVCIQRYAGVFPKGQEMYSKM-FYHEEKLRLFITFNFGLTMLEMKPDVKDKIS---SHEKPLIGCLYNSLYNQVVTACQGGIIYCWMVDTGQRVKTITEICGPQA--------ELTCITQDSTQTRLYTGATDGNVKIWDFNGHCYNTLIVANGNPV---DISQIVILKRCVLVFGFSKSITAFWTSSFKDHKVSPSPWKGVQTHKDDILSGASIPPHAVATGSYDGEIIIWNINSEQASRTMTQRSQDEMKEVKKLA-EQTIVRIKMAANAELKRAASNSIQQETDDKLDFIKAEIQNSIANRQXXXXXXXXXXXXXXXXXXXXDTVSDMQVQYKKMDVMFNISRLIYLESR-KKIKHGGGANLISCGGNGIVRFWNSAEGWLIGEFVA-HENASNII-MNTDVSNQYLVTGDMDGYIRVWDILSYCQTESENQKIMSP---------------------------PTLISQWQSHSDEISGISFCFKFSRTLIITSSADQSAALWELNGVLIGRFGQEHRW 2804
            +   S F +  G+++F   E+ N++ T G +  V +W+ Y+ ++P+ +L GH   +  V        + S    KI+++WD+     +Q Y  +        + + +Y+   LR  +     L  ++  P V+  ++   +H  P+   LYN L+  +V+      I  W   TG+R K I + C  +         E+T    D  +  L TGA DG++KIW++N    N ++V N + +   +++ ++ +   +L  G+ + +T F     +++   P  W   + H DDI          V T +Y GEII W + + Q  R  +        E+K  A E+  +R      + L  + ++S+Q     +         +++ NR  +     +                         D+  ++  +++L++R + +KH  G+  IS     I  + +   G  I EF+A H+    ++ M TD  N+YL TG   GYI+VW I+++C  ESE   +  P                           P L+S ++ H   I+ I+F       +I T S D S  LW   G  +G  G    W
Sbjct:  315 YDERSNFRIPLGVSTFFVAESHNIVVTGGPDTFVRIWDVYIPTEPSAILTGHNGGIVLVFVQPEENKVYSVDYQKIIKVWDLHEHTLLQTYGDLVRLIHHSETDLTYYYHSHLRELVVAGRKLISIKCCPRVRVDLTDGNTHAAPVSVVLYNRLFRNIVSCGLDSYIIVWDPWTGRR-KIIMKSCHTKMIYGEIIDIEITAACFDPLEQFLLTGARDGSLKIWNYN----NAVVVRNMSIMPDQEVTAVIWVVDRILAMGWDRQVTEFNDVVGREYG-DPKKWP--KFHTDDITCADVKLGEGVVTATYSGEIIFWKLETGQPYRRYSVMDPTRFIELKLTAEEEKFIRQSKRLASRLTHSGNHSLQTGRAGR---------STVLNRPEDNRDYGT-------------------------DIPISVQAVLFLQTRPQTLKH--GSVFISLDTGFIQVYSHHQRGGYIVEFLAVHKTGDCVLTMCTDRKNRYLYTGTAFGYIKVWYIVNFCVPESEKTHVCMPKLRLEFIFLRKELFMTRAKRAVRNQAEPLLVSSYKGHLKAINSIAFINL--PKIIFTGSHDYSCRLWTQGGRYLGTLGTVLPW 875          
BLAST of WD repeat-containing protein 49 vs. UniProt/SwissProt
Match: sp|Q9D565|WDR64_MOUSE (WD repeat-containing protein 64 OS=Mus musculus OX=10090 GN=Wdr64 PE=2 SV=2)

HSP 1 Score: 160.229 bits (404), Expect = 2.532e-38
Identity = 133/457 (29.10%), Postives = 209/457 (45.73%), Query Frame = 3
Query:  441 KDVIQRIVLVRNLNRYLTISKEGNVGLWGSDCKLQKVAKTHTESCRSRDLWVTDFAFLGNVNKVAVSFTSKEISFYDMNVKLEFNCQVKLENLFRIP------ICMDYWHHPDNNGEAIMAWGDTGGYINVILWSNISSSLFERVSSKASDKDENTXXXXXXXXXXXXXKTCTYFSHKAHQDWVRKVSYIPNLECFVSCATNWNTSMVICWMEKYNPSNSTSSEMAGIPESRGFSRTSCFTVHQGINSFAYNENLNLIATAGVNFQVCLWNPYVISKPNGLLRGHMASVTDVQFNKARGHLISFSKDKILRIWDVQ----LQVCIQRYAGVFPKGQEMYSKMFYHEEKLRLFITFNFGLTMLEMKP------DVKDKISSHEKPLIGCLYNSLYNQVVTACQGGIIYCWMVDTGQRVKTITEICGPQAELTCITQDSTQTRLYTGATDGNVKIWDFN 1763
            +DVI+ IV V  L+  +T S++G + ++ S    Q  +            W+T   +LG + ++ V+ T + I  +D   K + + Q   E+ F I       +C+     PD      +  GD GG++N      +SS  F    +K   K +               K       K H DWV K+ YIP L CF SC+ +   S+V+  +++    N    E               F + +G NSF Y    N+I T G +  + LW+P + +KP G L GHM S+T++  N+   H+IS S  K+ R+WD+Q    LQV      G  P   ++YS ++  +    + IT   G  +++M P      D K    +HE+ +   LYN  ++QV+T C   +I  W ++TG ++  I +  G   ELTC   D +     TGA +G VKIWDF 
Sbjct:  131 RDVIKCIVKVPQLDLLITASQKGLITVFNS----QDTS------------WITGCDYLGQLKRI-VATTERTIIVWDY--KAQGSSQ---EHYFVIKPMDHCLLCVCVVPLPDQLCRDDILLGDDGGFVNKF---TVSSDDFGLKQAKTKKKLQT---------QVLDSKNFKSVKRKLHNDWVMKIRYIPALNCFGSCSLDSVHSLVLESLKRLE-DNLPVRE---------------FAMPRGANSFCYCGKANVIVTGGDDKVLRLWHPNISTKPVGKLVGHMFSITEIVSNEKEQHVISLSSAKVFRVWDIQTLSVLQVFHDSQGG--PGDMQIYSMVY--DANHGMLIT---GSGVIDMYPLTRMIQDTKQVPHTHEREVNVTLYNKYFHQVLTVCSESVIKVWELETGLQIYQILDPHGLSIELTCAAIDESGYLFATGAYNGTVKIWDFG 530          
BLAST of WD repeat-containing protein 49 vs. UniProt/SwissProt
Match: sp|B7FF09|WDY_DROWI (WD repeat-containing protein on Y chromosome OS=Drosophila willistoni OX=7260 GN=WDY PE=4 SV=1)

HSP 1 Score: 160.229 bits (404), Expect = 2.657e-38
Identity = 140/608 (23.03%), Postives = 252/608 (41.45%), Query Frame = 3
Query: 1122 FSRTSCFTVHQGINSFAYNENLNLIATAGVNFQVCLWNPYVISKPNGLLRGHMASVTDVQFNKARGHLISFSKDKILRIWDVQLQVCIQRYAGVFPKGQEMYSKM-FYHEEKLRLFITFNFGLTMLEMKPDVKDKIS---SHEKPLIGCLYNSLYNQVVTACQGGIIYCWMVDTGQRVKTITEICGPQA--------ELTCITQDSTQTRLYTGATDGNVKIWDFNGHCYNTLIVANGN---PVDISQIVILKRCVLVFGFSKSITAFWTSSFKDHKVSPSPWKGVQTHKDDILSGASIPPHAVATGSYDGEIIIWNINSEQASRTMTQRSQDEMKEVKKLAEQTIVRIKMAANAELKRAASNSIQQ---ETDDKLDFIKAEIQNSIANRQXXXXXXXXXXXXXXXXXXXXDTVSDMQVQYKKMDVMFNISRLIYLESRKKIKHGGGANLISCGGNGIVRFWNSAEGWLIGEFVA-HENASNII-MNTDVSNQYLVTGDMDGYIRVWDILSYCQTESENQKIMSP---------------------------PTLISQWQSHSDEISGISFCFKFSRTLIITSSADQSAALWELNGVLIGRFGQEHRW 2804
            +   S F +  G+ +F   E+ N++ T G +  V +W+ Y+ ++P+ +L GH   +  V        + S    KI+++W++Q    +Q Y  +        + + +Y+   LR  I     L  ++  P V+  ++   +H  P+   LYN L+  +VT      I  W   TG+R K I + C  +         E+T    D  +  L TGA DG++KIW++N    N +++ N +     +++ ++ +   +L  G+ + +T F     +++   P  W   + H DDI  G       V T +Y GEII W + + Q  R  +        E+K   E+  ++      +    + S+ +          +D +       +A  Q                          +++   ++V  ++  +++L++R +  H G    IS     I  + +   G  + EF+A H+    ++ M TD  N++L TG   GYI+VW I++YC  E+E   +  P                           P L+S ++ H   I+ ISF       +IIT S D S  LW   G  +G  G    W
Sbjct:  322 YGDKSNFRIPLGVTTFFVAESHNIVVTGGPDTFVRIWDVYIPTEPSAILTGHNGGIVMVFVQPEENKVYSVDYQKIIKVWNLQEHTLLQTYGDLVRLIHHTETDLTYYYHSHLRELIVAGRKLISIKCCPRVRVDLTDGNTHAAPVSVVLYNRLFRNIVTCGLDSYIIVWDPWTGRR-KIIMKSCHTKMIYGETIDIEITAACFDPLEQFLLTGARDGSLKIWNYN----NAVVIRNMSIQPDQEVTAVIWVVERILAMGWDRQVTEFNDVEGREYG-DPKKWP--KFHTDDITCGDVKLGEGVVTATYSGEIIFWKLETGQPYRRYSVMEPKRFIELKLSDEEKQMKRSKRWASRAPHSGSHMMSHTGSHMGSNVDQMSGSRSRGLAILQ-----------------------GQEEIREYGVNVPISVQAVLFLQNRPQTLHHGSV-FISLDTGIIQVYSHHQRGGYMNEFLAVHKTGDCVLTMATDRKNRFLFTGTAFGYIKVWYIVNYCIPEAEKIHVCMPRLRLDFIFLRKETFLTRAKRVVRNQAEPLLVSSYKGHLKAINSISFINL--PKIIITGSHDYSCRLWTQGGRYLGTLGSVLPW 895          
BLAST of WD repeat-containing protein 49 vs. TrEMBL
Match: A0A1S3JWS0 (WD repeat-containing protein 49-like OS=Lingula unguis OX=7574 GN=LOC106176568 PE=4 SV=2)

HSP 1 Score: 1011.13 bits (2613), Expect = 0.000e+0
Identity = 516/1125 (45.87%), Postives = 722/1125 (64.18%), Query Frame = 3
Query:  117 LTENKLELKLNIKDLETLQEAFFMDG-SHNRSQHFNGEEFVEALSLVLCKGTREEYSDLFDKIDITREGYVDWEKFASHMLLEFYEKDDRTKSSSLPQWKELKTLSGPHKDVIQRIVLVRNLNRYLTISKEGNVGLWGSDCKLQKVAKTHTESCRSRDLWVTDFAFLGNVNKVAVSFTSKEISFYDMNV-KLEFNCQVKLENLFRIPICMDYWHHPDNNGEAIMAWGDTGGYINVILWSNISSSLFERVSSKASDKDENTX-------XXXXXXXXXXXXKTCTYFSHKAHQDWVRKVSYIPNLECFVSCATNWNTSMVICWMEKYNPSNSTSSEMAGIPESRGFSRTSCFTVHQGINSFAYNENLNLIATAGVNFQVCLWNPYVISKPNGLLRGHMASVTDVQFNKARGHLISFSKDKILRIWDVQLQVCIQRYAGVFPKGQEMYSKMFYHEEKLRLFITFNFGLTMLEMKPDVKDKISSHEKPLIGCLYNSLYNQVVTACQGGIIYCWMVDTGQRVKTITEICGPQAELTCITQDSTQTRLYTGATDGNVKIWDFNGHCYNTLIVANGNPVDISQIVILKRCVLVFGFSKSITAFWTSSFKDHKVSPSPWKGVQTHKDDILSGASIPPHAVATGSYDGEIIIWNINSEQASRTMTQRSQDEMKEVKKLAEQTIVRIKMAANAELKRAASNSIQQETDDKLDFIKAEIQNSIANRQXXXXXXXXXXXXXXXXXXXXDTVSDMQVQYKKMDVMFNISRLIYLESRKKIKHGGGANLISCGGNGIVRFWN--SAEGWLIGEFVAHENASNIIMNTDVSNQYLVTGDMDGYIRVWDILSYCQTESENQKIMSPPTLISQWQSHSDEISGISFCFKFSRTLIITSSADQSAALWELNGVLIGRFGQEHRWKLGSXXXXXXXXXXXXHEDEVVKQEED-KYKVDPNWYPDPEAIQNPSGYRINTWKDTNLGKDYQELRVRKRERIQPSSIPDLPYLYGEKIGRPTFGPFYSLNISSFEEIEDIEQPEFMEYPEKFFNETEEFLTKTARVPLLNETLKAVFDERSLL--PEYILEFEHKFRNRFQRHLSEAKVKLSLDDSNSFQEQLPRK---------AKTVRLKPIQE 3422
            + + K+E +LNI+DLE +Q+ F  DG  ++     N E+F EALS +L KG+R++Y++LFDKID+T+EG VDW+KFASHMLLEFYEKDDR KS+ +PQWK+LKTL  PHK+ IQ+I  ++N+NRY+ ISKEG V +W    KLQ+  KT TESCR RDLW++ F  L N+NK+A++FTSKEI+FYDM+  KLEFNCQ K++ L   P+C+DYW +P N  EA++ WGD GG +N +L+S  + +LFER ++ A +K E T+         +I++      K   Y  H  H +WVR+V Y PNL+ F+S +T+   ++VI W+EK               +S    +T+ F + QG+N   Y+E LNLIATAGVN QVCLWNPYV+SKPNG+LRGHMASV  VQFN  RG LISFSKDK+LRIWDVQLQVCIQR AG+FPKG E+YS ++  E + RLFITFN+ LT++EMK +VK++I SHEKP+   +YNSLYNQV+++CQ G +  WM+DTGQ+VK  T   G   E+T +  D ++TRLYTG+TDG VKIWDFNGHCY+TL  + G+P DI QI++LKR VLV G+++ IT F  ++ KD  V PS WKG Q H+DDIL+    PP+  AT SYDGEI+IWN+NSE AS+ + QR++   K   K    T++  +  A+ EL R  +      T +      A    +        +  +  S + T +  S   +S+ Q  Y+     + ++R+++LE+RK     G ANL+SCGGNG VRFWN  ++ G L+GEFV+H  A+++IM TD  NQYLVTGD+DG ++VW+I  YC  ++++     PP + + WQ H D I+ +  C +  R L++++S D S  LW++ G LIG FGQE  WK+   +    +      E+E     +  +   D +W P+  A   P  YR NTW  T LGK YQE R  KRER QP  +P+LPYL+ E+ G P  GPF +L ++  +E+  I++P+F+ +P K+F+E      ++ ++P L E+LK  FDE++L    +YIL++E + +   +  L     K  L         LP +         AK  +LKPIQ+
Sbjct:   34 MLDQKMENRLNIRDLEQVQDIFMADGDGYDNRLSLNREQFCEALSRLLTKGSRQDYAELFDKIDVTKEGQVDWDKFASHMLLEFYEKDDRVKSTQVPQWKDLKTLPSPHKETIQKIAYLKNINRYIAISKEGCVSMWDPSLKLQRTIKTGTESCRQRDLWMSHFVPLQNINKIALAFTSKEIAFYDMSSNKLEFNCQYKVQGLEHTPLCLDYWFNPKNTNEAVIVWGDVGGCVNALLFSTANIALFERPTAPAGEKQETTLNIQLKEISRTIDNREKAKYKNARYIRHHGHSEWVRQVKYAPNLDAFISVSTSNARAIVIGWIEKG--------------DSLRAMKTTAFHISQGVNGLDYHEGLNLIATAGVNHQVCLWNPYVVSKPNGVLRGHMASVIQVQFNTTRGQLISFSKDKVLRIWDVQLQVCIQRLAGMFPKGPEVYSVLYLDEIRNRLFITFNYQLTLMEMKAEVKNRILSHEKPICSVIYNSLYNQVISSCQAGTVVVWMIDTGQKVKQFTNTHGTN-EVTALALDQSETRLYTGSTDGTVKIWDFNGHCYHTLDCSEGHPADIGQIIVLKRNVLVVGWARHITIFRQNNLKDFHVLPSDWKGGQEHQDDILTACFSPPNRAATASYDGEIVIWNMNSEHASKHLNQRAK---KVTNKNRRSTLIPSR--ASRELTREGTFESVSPTRNPPTPRNATTPRNAPTPGTAPTPLSRASPQRTKSRMSVAAISEDQTGYE-----YAVTRVLFLEARKTHSASGTANLVSCGGNGWVRFWNTSTSAGTLMGEFVSHPQAASVIMATDQHNQYLVTGDVDGNMKVWNISEYCIRQADDVVTNQPP-MTASWQPHVDVITSLVMCERNERLLVVSASMDCSVQLWDIYGNLIGVFGQEDHWKIEPYVPKMEVDEETKEEEEEFADTDMIEPDADSHWEPEESATDQPESYRFNTWDKTCLGKTYQETRTHKRERRQPKVMPNLPYLHWERTGDPPAGPFAALEMNELQELNKIDKPDFIAHPHKYFSERSNNEEQSVKLPALAESLKTPFDEKTLFYKAKYILDYETRMKQYHKTVLEGGGKKQKLGGGKIAIPTLPNQSQAPPSRAPAKPQKLKPIQQ 1132          
BLAST of WD repeat-containing protein 49 vs. TrEMBL
Match: A0A1S3JX59 (WD repeat-containing protein 49 OS=Lingula unguis OX=7574 GN=LOC106176875 PE=4 SV=1)

HSP 1 Score: 1010.75 bits (2612), Expect = 0.000e+0
Identity = 516/1125 (45.87%), Postives = 722/1125 (64.18%), Query Frame = 3
Query:  117 LTENKLELKLNIKDLETLQEAFFMDG-SHNRSQHFNGEEFVEALSLVLCKGTREEYSDLFDKIDITREGYVDWEKFASHMLLEFYEKDDRTKSSSLPQWKELKTLSGPHKDVIQRIVLVRNLNRYLTISKEGNVGLWGSDCKLQKVAKTHTESCRSRDLWVTDFAFLGNVNKVAVSFTSKEISFYDMNV-KLEFNCQVKLENLFRIPICMDYWHHPDNNGEAIMAWGDTGGYINVILWSNISSSLFERVSSKASDKDENTX-------XXXXXXXXXXXXKTCTYFSHKAHQDWVRKVSYIPNLECFVSCATNWNTSMVICWMEKYNPSNSTSSEMAGIPESRGFSRTSCFTVHQGINSFAYNENLNLIATAGVNFQVCLWNPYVISKPNGLLRGHMASVTDVQFNKARGHLISFSKDKILRIWDVQLQVCIQRYAGVFPKGQEMYSKMFYHEEKLRLFITFNFGLTMLEMKPDVKDKISSHEKPLIGCLYNSLYNQVVTACQGGIIYCWMVDTGQRVKTITEICGPQAELTCITQDSTQTRLYTGATDGNVKIWDFNGHCYNTLIVANGNPVDISQIVILKRCVLVFGFSKSITAFWTSSFKDHKVSPSPWKGVQTHKDDILSGASIPPHAVATGSYDGEIIIWNINSEQASRTMTQRSQDEMKEVKKLAEQTIVRIKMAANAELKRAASNSIQQETDDKLDFIKAEIQNSIANRQXXXXXXXXXXXXXXXXXXXXDTVSDMQVQYKKMDVMFNISRLIYLESRKKIKHGGGANLISCGGNGIVRFWN--SAEGWLIGEFVAHENASNIIMNTDVSNQYLVTGDMDGYIRVWDILSYCQTESENQKIMSPPTLISQWQSHSDEISGISFCFKFSRTLIITSSADQSAALWELNGVLIGRFGQEHRWKLGSXXXXXXXXXXXXHEDEVVKQEED-KYKVDPNWYPDPEAIQNPSGYRINTWKDTNLGKDYQELRVRKRERIQPSSIPDLPYLYGEKIGRPTFGPFYSLNISSFEEIEDIEQPEFMEYPEKFFNETEEFLTKTARVPLLNETLKAVFDERSLL--PEYILEFEHKFRNRFQRHLSEAKVKLSLDDSNSFQEQLPRK---------AKTVRLKPIQE 3422
            + + K+E +LNI+DLE +Q+ F  DG  ++     N E+F EALS +L KG+R++Y++LFDKID+T+EG VDW+KFASHMLLEFYEKDDR KS+ +PQWK+LKTL  PHK+ IQ+I  ++N+NRY+ ISKEG V +W    KLQ+  KT TESCR RDLW++ F  L N+NK+A++FTSKEI+FYDM+  KLEFNCQ K++ L   P+C+DYW +P N  EA++ WGD GG +N +L+S  + +LFER ++ A +K E T+         +I++      K   Y  H  H +WVR+V Y PNL+ F+S +T+   ++VI W+EK               +S    +T+ F + QG+N   Y+E LNLIATAGVN QVCLWNPYV+SKPNG+LRGHMASV  VQFN  RG LISFSKDK+LRIWDVQLQVCIQR AG+FPKG E+YS ++  E + RLFITFN+ LT++EMK +VK++I SHEKP+   +YNSLYNQV+++CQ G +  WM+DTGQ+VK  T   G   E+T +  D ++TRLYTG+TDG VKIWDFNGHCY+TL  + G+P DI QI++LKR VLV G+++ IT F  ++ KD  V PS WKG Q H+DDIL+    PP+  AT SYDGEI+IWN+NSE AS+ + QR++   K   K    T++  +  A+ EL R  +      T +      A    +        +  +  S + T +  S   +S+ Q  Y+     + ++R+++LE+RK     G ANL+SCGGNG VRFWN  ++ G L+GEFV+H  A+++IM TD  NQYLVTGD+DG ++VW+I  YC  ++++     PP + + WQ H D I+ +  C +  R L++++S D S  LW++ G LIG FGQE  WK+   +    +      E+E     +  +   D +W P+  A   P  YR NTW  T LGK YQE R  KRER QP  +P+LPYL+ E+ G P  GPF +L ++  +E+  I++P+F+ +P K+F+E      ++ ++P L E+LK  FDE++L    +YIL++E + +   +  L     K  L         LP +         AK  +LKPIQ+
Sbjct:   34 MLDQKMENRLNIRDLEQVQDIFMADGDGYDNRLSLNREQFCEALSRLLTKGSRQDYAELFDKIDVTKEGQVDWDKFASHMLLEFYEKDDRVKSTQVPQWKDLKTLPSPHKETIQKIAYLKNINRYIAISKEGCVSMWDPSLKLQRTIKTGTESCRQRDLWMSHFVPLQNINKIALAFTSKEIAFYDMSSNKLEFNCQYKVQGLEHTPLCLDYWFNPKNTNEAVIVWGDVGGCVNALLFSTANIALFERPTAPAGEKQETTLNIQLKEISRTIDNREKAKYKNARYIRHHGHSEWVRQVKYAPNLDAFISVSTSNARAIVIGWIEKG--------------DSLRAMKTTAFHISQGVNGLDYHEGLNLIATAGVNHQVCLWNPYVVSKPNGVLRGHMASVIQVQFNTTRGQLISFSKDKVLRIWDVQLQVCIQRLAGMFPKGPEVYSVLYLDEIRNRLFITFNYQLTLMEMKAEVKNRILSHEKPICSVIYNSLYNQVISSCQAGTVVVWMIDTGQKVKQFTNTHGTN-EVTALALDQSETRLYTGSTDGTVKIWDFNGHCYHTLDCSEGHPADIGQIIVLKRNVLVVGWARHITIFRQNNLKDFHVLPSDWKGGQEHQDDILTACFSPPNRAATASYDGEIVIWNMNSEHASKHLNQRAK---KVTNKNRRSTLIPSR--ASRELTREGTFESVSPTRNPPTPRNATTPRNAPTPGTAPTPLSRASPQRTKSRMSVAAISEDQTGYE-----YAVTRVLFLEARKSHSASGTANLVSCGGNGWVRFWNTSTSAGTLMGEFVSHPQAASVIMATDQHNQYLVTGDVDGNMKVWNISEYCIRQADDVVTNQPP-MTASWQPHVDVITSLVMCERNERLLVVSASMDCSVQLWDIYGNLIGVFGQEDHWKIEPYVPKMEVDEETKEEEEEFADTDMIEPDADSHWEPEESATDQPETYRFNTWDKTCLGKTYQETRTHKRERRQPKVMPNLPYLHWERTGDPPAGPFAALEMNELQELNKIDKPDFIAHPHKYFSERSNNEEQSVKLPALAESLKTPFDEKTLFYKAKYILDYETRMKQYHKTVLEGGGKKQKLGGGKIAIPTLPNQSQAPPSRAPAKPQKLKPIQQ 1132          
BLAST of WD repeat-containing protein 49 vs. TrEMBL
Match: R7UEX8 (WD_REPEATS_REGION domain-containing protein OS=Capitella teleta OX=283909 GN=CAPTEDRAFT_229382 PE=4 SV=1)

HSP 1 Score: 996.497 bits (2575), Expect = 0.000e+0
Identity = 484/1025 (47.22%), Postives = 682/1025 (66.54%), Query Frame = 3
Query:  279 YSDLFDKIDITREGYVDWEKFASHMLLEFYEKDDRTKSSSLPQWKELKTLSGPHKDVIQRIVLVRNLNRYLTISKEGNVGLWGSDCKLQKVAKTHTESCRSRDLWVTDFAFLGNVNKVAVSFTSKEISFYDMNVKLEFNCQVKLENLFRIPICMDYWHHPDNNGEAIMAWGDTGGYINVILWSNISSSLFERVSSKASDKDENTXXXXXXXXXXXXXKTCTYFSHKAHQDWVRKVSYIPNLECFVSCATNWNTSMVICWMEKYNPSNSTSSE---MAGIPESRGFSRTSCFTVHQGINSFAYNENLNLIATAGVNFQVCLWNPYVISKPNGLLRGHMASVTDVQFNKARGHLISFSKDKILRIWDVQLQVCIQRYAGVFPKGQEMYSKMFYHEEKLRLFITFNFGLTMLEMKPDVKDKISSHEKPLIGCLYNSLYNQVVTACQGGIIYCWMVDTGQRVKTITEICGPQAELTCITQDSTQTRLYTGATDGNVKIWDFNGHCYNTLIV-ANGNPVDISQIVILKRCVLVFGFSKSITAFWTSSFKDHKVSPSPWKGVQTHKDDILSGASIPPHAVATGSYDGEIIIWNINSEQASRTMTQRSQDEMKEVKKLAEQTIVRIKMAANAELKRAASNSIQQETDDKLDFIKAEIQNSIANRQXXXXXXXXXXXXXXXXXXXXDTVSDMQVQYKKMDVMFNISRLIYLESRKKIKHGGGANLISCGGNGIVRFWNSAEGWLIGEFVAHENASNIIMNTDVSNQYLVTGDMDGYIRVWDILSYCQTESENQKIMSPPTLISQWQSHSDEISGISFCFKFSRTLIITSSADQSAALWELNGVLIGRFGQEHRWKLGSXXXXXXXXXXXXHEDEVVKQEEDKYKVDPNWYPDPEAIQNPSGYRINTWKDTNLGKDYQELRVRKRERIQPSSIPDLPYLYGEKIGRPTFGPFYSLNISSFEEIEDIEQPEFMEYPEKFFNETEEFLTKTARVPLLNETLKAVFDERSLLPEYILEFEHKFRNRFQRHLSEAKVK 3341
            ++DLFDK+D+T+EG VDW+KFASHMLLEFYE+D+R KS+ +PQWK+L+TL  PHK++IQR+  ++N NRY++ISKEG V +WG + KLQ+  KT T++CR+RDLW+TDF  L N+NK+A++FTSKEI+ YD++ KLEFNCQ K++ +   P+ ++YW +P N  EAI+ WGDT G +N + +++ + +LFER  + + +K E  + + + D+I    K+  +  H+ H +WVR+V Y  NLECF+SCAT WN S+VI WMEK+  + +  +E    + +P+     RT+ F + QG+N F Y+E LNLIATAGVN  VCLWNPYV+SKPNG+LRGHMASV  VQFNK R  LISFSKDK+LRIWDVQLQV IQR AG+FPKG E+ S +++ E   RLFITFN+ LT++EMK ++ D++ SHEKP++  LYN+ YNQVV+ACQGG I  WM DTGQ+VK  T+  G  +E+T + QD +QTR+YTG+TDG VKIWDFNGHCY+TL   ++G P DI QI+ LKR ++V G+++ IT F  ++F+D  + PS WKG Q H+DDIL+ A   P+ +A+GSYDGEI+ WN NSEQAS+ + QR +  M   K     + +R  M+++   +  ++ +++     +                                     T S +  + +  +  F I+ L +L  RK     GGANL+SCGGNG VRFWN+    L+ EF AH    +++M  D  + ++ TGD+DG I+VWDI  YC  +SE+  I +PP L SQ+  H D +S +    +  RTLI+++SAD S  LW++ G  IG FGQE  WK+    E   +   + H +E   + E +   +  W PD  A + P  YRINTW+ T+LGKDYQELRVRKRER QP  I DLPYL+ EK G+P  GPF +LN +   ++  + QP+FM +P ++F+E     ++  R+P L ETL A FDE+SL P+YI++FE+K ++   R L+EA+ +
Sbjct:    6 FADLFDKVDVTKEGTVDWDKFASHMLLEFYERDNRVKSTQVPQWKDLRTLPSPHKEIIQRLAYLKNSNRYISISKEGCVSMWGQNLKLQRNLKTGTDTCRARDLWMTDFIPLQNINKIALAFTSKEIAIYDLSAKLEFNCQFKVQGMEHTPLSLEYWSNPMNVNEAILTWGDTSGAVNALHFNSANIALFERPPAPSGEKQETCLNVHLKDVIKKKYKSARFTKHQGHSEWVRQVKYSANLECFISCATTWNNSLVIGWMEKHQSNQNMKTEDNNCSILPKE--VVRTTTFQLPQGVNGFDYHEQLNLIATAGVNHHVCLWNPYVVSKPNGVLRGHMASVIQVQFNKCRNQLISFSKDKVLRIWDVQLQVAIQRLAGMFPKGPEVSSILYFDERMNRLFITFNYQLTVMEMKVEITDRVMSHEKPVVAALYNATYNQVVSACQGGTIIMWMADTGQKVKQFTQAHG-NSEVTTLAQDHSQTRIYTGSTDGTVKIWDFNGHCYHTLHCGSDGQPADIGQILSLKRSLIVVGWARYITVFRDANFRDFHIEPSDWKGGQEHQDDILALAFSGPNTLASGSYDGEIVTWNNNSEQASKHLNQRGRKLMTRQKTF---STLR-DMSSDLGFESCSNTNMRGRPKSR-------------------------------------TASRLSTEEEANEYGFAITCLAFLTGRKGSSAKGGANLVSCGGNGWVRFWNTNNNKLLAEFTAHSQVGSLVMVVDEHSHWMATGDVDGLIKVWDISQYCMYDSEDSIITTPPPLKSQFIPHIDALSTLEIFVRNERTLILSASADCSVQLWDIYGNQIGVFGQEGHWKVEPYNEQDEVENEDRHNEEDEIRAEVEADHESEWEPDELATERPEDYRINTWEKTHLGKDYQELRVRKRERRQPEIIKDLPYLHWEKTGQPPAGPFAALNTTELSDVGTLNQPDFMHHPHRYFSERPSTASQNKRLPSLAETLNAAFDEKSLFPKYIMDFENKMKHHHTRTLAEAQKR 986          
BLAST of WD repeat-containing protein 49 vs. TrEMBL
Match: A0A2T7PSF0 (Uncharacterized protein OS=Pomacea canaliculata OX=400727 GN=C0Q70_03331 PE=4 SV=1)

HSP 1 Score: 969.533 bits (2505), Expect = 0.000e+0
Identity = 505/1041 (48.51%), Postives = 673/1041 (64.65%), Query Frame = 3
Query:   99 KESHTPL-TENKLELKLNIKDLETLQEAFFMDG-SHNRSQHFNGEEFVEALSLVLCKGTREEYSDLFDKIDITREGYVDWEKFASHMLLEFYEKDDRTKSSSLPQWKELKTLSGPHKDVIQRIVLVRNLNRYLTISKEGNVGLWGSDCKLQKVAKTHTESCRSRDLWVTDFAFLGNVNKVAVSFTSKEISFYDMNVKLEFNCQVKLENLFRIPICMDYWHHPDNNGEAIMAWGDTGGYINVILWSNISSSLFERVSSKASDKDENTXXXXXXXXXXXXXKTCTYFSHKAHQD-----WVRKVSYIPNLECFVSCATNWNTSMVICWMEKYNPSNSTSSEMAGIPESR--GFSRTSCFTVHQGINSFAYNENLNLIATAGVNFQVCLWNPYVISKPNGLLRGHMASVTDVQFNKARGHLISFSKDKILRIWDVQLQVCIQRYAGVFPKGQEMYSKMFYHEEKLR-------LFITFNFGLTMLEMKPDVKDKISSHEKPLIGCLYNSLYNQVVTACQGGIIYCWMVDTGQRVKTITEICGPQAELTCITQDSTQTRLYTGATDGNVKIWDFNGHCYNTLIVANGNPVDISQIVILKRCVLVFGFSKSITAFWTSSFKDHKVSPSPWKGVQTHKDDILSGASIPPHAVATGSYDGEIIIWNINSEQA---------------------SRTMTQRSQDEMKE--VKKLAEQTIVRIKMAANAELKRAASNSIQQETDDKLDFIKAEIQNSIANRQXXXXXXXXXXXXXXXXXXXXDTVSDMQVQYKKMDVMFNISRLIYLESRKKIKHGGGANLISCGGNGIVRFWNSAEGWLIGEFVAHENASNIIMNTDVSNQYLVTGDMDGYIRVWDILSYCQTESENQKIMSPPTLISQWQSHSDEISGISFCFKFSRTLIITSSADQSAALWELNGVLIGRFGQEHRWKLGSXXXXXXXXXXXXHEDE---VVKQEEDKYKVDPNWYPDPEAIQNPSGYRINTWKDTNLGKDYQELRVRKRERIQPSSIPDLPYLYGEKIGRPTFGPF 3095
            +E   PL  + KLE +L +KDLE L+ +F ++G  ++     N ++F EALSL+L KG+REEY +LFDKID+TREG VDW+KFASHMLLEFYE+DDR KS+ +PQWK+LK+L  PHK++IQR+  ++N +RY+ ISKEG V +WG D K+Q++ +T T+SCR+RDLWVT F  L N+NK+A+SFTSKEI+ YD++ KLEFNCQ K+ +L   P+C+DYW +PDN  EA++ WGD GG++N++ +++ + +LFER  + A +K E  + + ++DI+ G  K   Y S++AH++     WVR+V Y   LECF+SCAT    ++VI WMEK++  N + +   G   SR  G  R S F + QG+NSF Y++ LNLIATAG N  VCLWNPYV+SKPNG+LRGHMASV  VQF K RG LISFSKDK+LRIWDVQLQVCIQR AG+FPKG E+ S +F+ E K R       LFITFN+ +T+L+MK +VKD+I SHEKP+I  LYN++YNQ+V+ CQ G +  WM DTGQ+VK  ++I G  +E+TC++QD +Q+RL+TG+TDG VK+WDFNGHCY+ L  A G P D+ QI+ LK  +LV G++K IT F  SS ++  V P+ WKG Q H +DILS   I P  +A+GSYDGEIIIWN NSE A                     SR  TQ SQ    E  +   +E+ I  +    ++   RA S         K+     E QN                                          + + +LI+LE+R+    GGGANL+SCGGNG VRFWNS+   L+ EF+AH+ + +IIM TD  NQYLVT DMDG I+VWDIL Y  T   ++ I+  P L SQ+Q H D I+ ++   +  R LI ++S+D S ALW++ G  IG FGQE  W++   +    +      E E    VK        D  W PD  AI NP  YRINTW+ T LGKDYQELRV+KRER QPS+IPDLPYL+ E+ G P  GP+
Sbjct:   24 REERKPLGLDQKLENRLTMKDLERLKSSFMVEGEGYDNRLSLNRDQFCEALSLLLKKGSREEYGELFDKIDVTREGIVDWDKFASHMLLEFYERDDRVKSTQVPQWKDLKSLPSPHKEIIQRMTFLKNTSRYIAISKEGCVSMWGIDLKMQRMLRTGTDSCRARDLWVTHFIPLQNINKIALSFTSKEIAIYDLSSKLEFNCQYKIADLLYTPLCLDYWSNPDNANEAVLVWGDLGGFVNILFFNSANIALFERPPAPAGEKQEPCLNVHLHDIVIGKYKNAAYTSYEAHKENGKGEWVREVRYSHYLECFISCATTSPNAVVIGWMEKHSSVNQSVTLSKGGESSRKKGIQRKSEFQISQGVNSFDYHDGLNLIATAGANCHVCLWNPYVVSKPNGVLRGHMASVIQVQFVKNRGQLISFSKDKVLRIWDVQLQVCIQRLAGMFPKGPEVSSVLFFDEAKDRSGLDRNRLFITFNYQITVLDMKIEVKDRIMSHEKPIIAVLYNTVYNQLVSLCQAGTLVMWMPDTGQKVKQFSQIHG-NSEVTCMSQDQSQSRLFTGSTDGTVKVWDFNGHCYHLLECAGGQPADVCQILSLKHSILVVGWTKCITVFRNSSLREFHVQPADWKGGQEHVEDILSVDFIGPSTLASGSYDGEIIIWNTNSEHASRHMMQRSRRGLRSRSKSFALSREPTQVSQTTSYEERMNTFSEKEISSLSKVTSSRRSRAMS---------KVSLDSNEEQNEFG---------------------------------------WAVVKLIFLEARRGNSAGGGANLVSCGGNGWVRFWNSSHNSLLAEFLAHQQSGSIIMATDKMNQYLVTADMDGLIKVWDILEYA-TCHVDETIVELPPLKSQFQPHQDMINSLAVFERSDRYLIASASSDCSVALWDIYGNRIGIFGQEEHWRIEPYMPPLQLDENVDFEREREVTVKDLMMDSDEDSQWEPDEAAINNPETYRINTWEKTVLGKDYQELRVQKRERRQPSTIPDLPYLHWERTGAPPAGPY 1014          
BLAST of WD repeat-containing protein 49 vs. TrEMBL
Match: A0A210PY34 (WD repeat-containing protein 49 OS=Mizuhopecten yessoensis OX=6573 GN=KP79_PYT23138 PE=4 SV=1)

HSP 1 Score: 959.133 bits (2478), Expect = 0.000e+0
Identity = 503/1100 (45.73%), Postives = 701/1100 (63.73%), Query Frame = 3
Query:   99 KESHTPLTENKLELKLNIKDLETLQEAFFMDG-SHNRSQHFNGEEFVEALSLVLCKGTREEYSDLFDKIDITREGYVDWEKFASHMLLEFYEKDDRTKSSSLPQWKELKTLSGPHKDVIQRIVLVRNLNRYLTISKEGNVGLWGSDCKLQKVAKTHTESCRSRDLWVTDFAFLGNVNKVAVSFTSKEISFYDMNVKLEFNCQVKLENLFRIPICMDYWHHPDNNGEAIMAWGDTGGYINVILWSNISSSLFERVSSKASDKDENTXXXXXXXXXXXXX-KTCTYFSHKAH-QDWVRKVSYIPNLECFVSCATNWNTSMVICWMEKYNPSNSTSSEMAGIPESRGFSRTSCFTVHQGINSFAYNENLNLIATAGVNFQVCLWNPYVISKPNGLLRGHMASVTDVQFNKARGHLISFSKDKILRIWDVQLQVCIQRYAGVFPKGQEMYSKMFYHE-------EKLRLFITFNFGLTMLEMKPDVKDKISSHEKPLIGCLYNSLYNQVVTACQGGIIYCWMVDTGQRVKTITEICGPQAELTCITQDSTQTRLYTGATDGNVKIWDFNGHCYNTLIVANGNPVDISQIVILKRCVLVFGFSKSITAFWTSSFKD-----HKVSPSPWKGVQTHKDDILSGASIPPHAVATGSYDGEIIIWNINSEQASRTMTQRSQDEM-----KEVKKLAEQTIVRIKMAANAELKRAASNSIQQETDDKLDFIKAEIQNSIANRQXXXXXXXXXXXXXXXXXXXXDTVSDMQVQYKKMDVMFNISRLIYLESRKKIKHGGGANLISCGGNGIVRFWNSAEGWLIGEFVAHENASNIIMNTDVSNQYLVTGDMDGYIRVWDILSYCQTESENQKIMSPPTLISQWQSHSDEISGISFCFKFSRTLIITSSADQSAALWELNGVLIGRFGQEHRWKLGS---XXXXXXXXXXXXHEDEVVKQEEDKYKVDPNWYPDPEAIQNPSGYRINTWKDTNLGKDYQELRVRKRERIQPSSIPDLPYLYGEKIGRPTFGPFYSLNISSFEEIEDIEQPEFMEYPEKFFNETEEFLTKTARVPLLNETLKAVFDERSLLPEYILEFEHKFRNRFQRHLSE 3329
            K+   PL + KLE +L +KDL  LQ AF  +G  ++       ++F EALS++L KGTREEY +LFDK+D+ REG VDW+KFASHMLLEFYEKDDR KS+ +PQWK+LK+L  PHKDVIQ++V ++N N+Y+ +SKEG + +W  D K  +  KT T++C+ RDLW+T F  L N+NK+A++FTSKEIS YDM+ KL+FNCQ K++ L   P+ +DYW +P+N  EA++ WGD GG++NVI +++ + +LFER  + A +K E  + + + D+I     K   Y  H+AH ++WVR+V Y   LECF+SC+T    SMVI WMEK+  ++ T S+   I  S+   R S F + QGIN+F YN+ LNLIATAGVN  VCLWNPYV+SKPNG+LRGHMASV  V F K+R  LISFSKDK+LRIWDVQLQVCIQR AG+FPKG E+YS +++ E       EK RL ITFN+ LTM+EMK +++D+I SH+KP+I  +YN+ YNQVV+ CQ G +  WM+DTGQ+VK  +   G  AE+TC++QD T T+L+TG+TDG VK+WDFNGH  ++L  A G P D+ Q++ LKR ++V G+++ +T F  S+ +D      +V+PS WKG Q H +DIL  A   P+ + TGSYDGEI++WN NSEQASR ++QRS+ +M     K +     + + R+         R+  NS  + T                                          ++   + ++ +  F +SRLI+LESRK    GG ANL+SCGG+G+VRFWN++   L  EF AH N S IIM TD  NQ+LVTGD DG I+VW+I  YC     +  + S P +  Q+Q+H+D I+ I  C +  R+LIIT+S+D S A++++ G  IG FGQE  WK+ +     E          E E  ++EE + +V+  W PD  AI  P  +RINTW  T LGK+YQE RVRKRER QP +IP+LPYL  EK G+   GP+ +L      + +   +P+ +        +T        ++P L +TLK    E+ + P+YIL+FE K ++  +  L++
Sbjct:   32 KQEKKPLMD-KLENRLTMKDLNKLQRAFMTEGDGYDNKLALYRDQFCEALSILLEKGTREEYGELFDKVDVAREGSVDWDKFASHMLLEFYEKDDRVKSTQVPQWKDLKSLPSPHKDVIQKVVFLKNTNKYIAVSKEGTISIWPQDMKQSRSFKTGTDTCKGRDLWITHFCALQNINKLALAFTSKEISIYDMSTKLDFNCQYKIQGLPYTPLTLDYWSNPNNPNEALLVWGDVGGFVNVIFFNSANIALFERPPAPAGEKQEPCLSVQLQDVIGEQTYKNAKYTVHEAHKKEWVRQVRYSQYLECFISCSTTNINSMVIGWMEKH--TSVTPSKNQQI--SKEILRKSEFHIPQGINAFDYNQTLNLIATAGVNHHVCLWNPYVVSKPNGVLRGHMASVIQVHFMKSRAQLISFSKDKVLRIWDVQLQVCIQRLAGMFPKGPEVYSCLYFDEQRERSGLEKNRLLITFNYQLTMMEMKAEIRDRIMSHDKPVISAIYNTTYNQVVSVCQSGTLIIWMIDTGQKVKQFSSAHG-NAEVTCLSQDPTGTKLFTGSTDGTVKMWDFNGHNSHSLECAGGQPADVGQVLNLKRSIVVVGWARYVTIFRDSALRDTGALFAQVTPSEWKGGQEHPEDILCCAFTAPNTMVTGSYDGEIVVWNTNSEQASRHLSQRSRRKMLKSRTKSIVSTTNRDVARVSETDAESRPRSRPNSRPKST------------------------------------------TNGGTKEEQKEFGFAVSRLIFLESRKTNSGGGSANLMSCGGSGMVRFWNTSTSSLAAEFQAHTNGS-IIMATDKLNQWLVTGDADGLIKVWEITEYCMHSQTDVILKSSPPMKCQYQAHTDMINSIDMCERNERSLIITASSDCSVAVFDVRGNKIGVFGQEEHWKIETYDPAEELEDEEGNSEEEPEDEEEEELEVEVESVWEPDERAITEPGTHRINTWDSTCLGKNYQETRVRKRERKQPGTIPNLPYLTWEKTGQAPAGPYSALETQVLLDFDPPSKPDVVS-----MTQTASHPINIPKLPALVDTLKQPVPEKEIFPKYILDFEAKMKSYHKMQLNQ 1077          
BLAST of WD repeat-containing protein 49 vs. Ensembl Cavefish
Match: wdr95 (WD repeat-containing protein on Y chromosome-like [Source:NCBI gene;Acc:103021898])

HSP 1 Score: 262.692 bits (670), Expect = 1.057e-71
Identity = 201/682 (29.47%), Postives = 348/682 (51.03%), Query Frame = 3
Query:  117 LTENKLELKLNIKDLETLQEAFFMDGSHNRSQHFNGEEFVEALSLVLCKGTRE----EYSDLFDKIDITREGYVDWEKFASHMLLEFYEKDD---RTKSSSLPQWKELKTLSGPHKDVIQRIVLVRNLNRYLTISKEGNVGLWGSDCKLQKVAKT-HTESCRSRDLWVTDFAFLGNVNKVAVSFTSKEISFYDMNVKLEFNCQVKLENLFRIPICMDY-WHHPDNNGEAIMAWGDTGGYINVILWSNISSSLFERVSSKASDKDENTXXXXXXXXXXXXXKTCTYFSHKAHQDWVRKVSYIPNLECFVSCATNWNTSMVI-CWMEKYNPSNSTSSEMAGIPES--------RGFS------RTSC----FTVHQGINSFAYNENLNLIATAGVNFQVCLWNPYVISKPNGLLRGHMASVTDVQFNKARGHLISFSKDKILRIWDVQLQVCIQRYAGVFPKGQEMYSKM---FYHEEKLRLFITFNFGLTMLEMKPDVKDK---ISSHEKPLIGCLYNSLYNQVVTACQGGIIYCWMVDTGQRVKTITEICGPQAELTCITQDSTQTRLYTGATDGNVKIWDF-NGHCYNTLIVANGNP--VDISQIVILKRC-VLVFGFSKSITAFWTSSFKDHKVS-PSP-WKG--VQTHKDDILSGASIPPHAVATGSYDGEIIIWNINS 2036
            L++ K+E ++++++L  L+ AF  D     ++  +   F + +    C G R+    +  +LF KID + +G V+W++F ++M LE+ EK++   R+K  +      +K LS  H + I +I  + +    +T+ ++G V  W S  +L+K     H      +  W TD   +   NK+ +    +EI  Y+++  LE +CQ+   +L  +P+ +DY +  PD   E  + +GD  G +++IL +++  +L  R+  K   K EN   ISI+  +       TY   K H+DWV KV Y  ++   VS + +  +++VI C +    PS +   +M  I E+         GF       R +C    F++++G+ +F +    NL+ T G++  + +WNPYV   P G+L+GH A +  +      G + S S D   RIWD+Q Q C+       PK   +  ++    Y      L+I+ +  L +L +K   + +    +SH++ ++ C Y++ + QVV+  +G +I  W VDTG  +       G  A +TC+T D    RL TG  DG ++IW+F NGHC  TL   +G P   D   + + +   V+  G+++ I  +  S+     V  P P W+   ++ H++D+L  A  PP+ +ATGSYDGEII+WN+ S
Sbjct:  131 LSKLKIEQRVSLENLTKLKLAF-EDYEKAGTRSLDLPRFRQTIRR--CLGLRDITDAQIRELFMKIDYSGQGSVEWDEFCTYMQLEYTEKEELVVRSKQVAFALPATMKPLS--HGEPILKIHQISD-GMIVTLKEDGAVSYWSSTLQLRKSKSVFHERPIGRKAKWATDLVTMPQYNKLIIGTGDREIQLYELS-SLEPHCQIN--SLETVPLKLDYCYTGPD---ECAVVYGDAQGCVSIILMTSVGETL--RLWKKLP-KVENVPSISIDHAVQS--PNITYIRWKVHEDWVTKVKYFQSIPAVVSTSNHEASALVIGCIL----PSTNIEQQMREIKEACREGKGKKAGFGVSSPQQRVACDQTVFSIYKGVKTFDFCTTRNLLITGGMDRLIRMWNPYVPGSPTGILKGHSAPIFYLHIATEDGRVFSVSTDNSARIWDIQDQSCL---FAAHPKASFLRGELTACLYSPAVRGLYISTD-SLALLSLKTKAEPQGSYTTSHKEAVLCCGYSAGFRQVVSCSEGSVIKVWDVDTGNEMFEFGGAHGLSA-VTCMTFDPKGRRLVTGGRDGCLRIWNFNNGHCLKTLSREDGAPEICDCCYLQVHRNTFVMSVGWARRIDVYLDSAEDTRHVQRPKPAWEDDLMKGHREDVLCVAQCPPYLLATGSYDGEIIMWNLVS 786          

HSP 2 Score: 67.3958 bits (163), Expect = 1.027e-10
Identity = 43/131 (32.82%), Postives = 62/131 (47.33%), Query Frame = 3
Query: 2433 NGIVRFWNSAEGWLIGEFVAHENASNI-----IMNTDVSNQYLVTGDMDGYIRVWDILSYCQTESENQKIMSPPTLISQWQSHSDEISGISFCFKFSRTLIITSSADQSAALWELNGVLIGRFGQEHRWKL 2810
             G V FWN   G   G+FV   NAS +      +     ++ L  GD  GY+ V+DI  +C           PP  ++ W++H   I+G+      S  +++TSS D +  LW + G  IG FGQ  RW L
Sbjct:  838 QGQVHFWNVQNG---GKFVQSFNASRLQQQIRKLAVTADDRLLFAGDDVGYVCVYDI-QHCALALRQ----DPPPTVNFWRAHISSITGLHLIE--SEQVLLTSSTDCTVRLWSITGEFIGTFGQRERWSL 958          
BLAST of WD repeat-containing protein 49 vs. Ensembl Cavefish
Match: ENSAMXT00000043902.1 (pep primary_assembly:Astyanax_mexicanus-2.0:APWO02002257.1:21799:28727:-1 gene:ENSAMXG00000036864.1 transcript:ENSAMXT00000043902.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 204.142 bits (518), Expect = 4.379e-58
Identity = 110/293 (37.54%), Postives = 171/293 (58.36%), Query Frame = 3
Query:  129 KLELKLNIKDLETLQEAFFMDGSHNRSQHFNGEEFVEALSLVLCKGTREEYSDLFDKIDITREGYVDWEKFASHMLLEFYEKDDRTKSSSLPQWKELKTLSGPHKDVIQRIVLVRNLNRYLTISKEGNVGLWGS-DCKLQKVAKTHTESCRSRDLWVTDFAFLGNVNKVAVSFTSKEISFYDMNVKLEFNCQVKLENLFRIPICMDYWHHPDNNGEAIMAWGDTGGYINVILWSNISSSLFERVSSKASDKDENTXXXXXXXXXXXXXKTCTYFSHKAHQ-DWVRKVSYIPNL 1001
            +LE +L+ +DL  +Q  F    S +        EFVE    V+ +G++EEY  LFD +D++REG+V+WE+  S+ LL   EKD+  K++++ +W+  +TL  PH+D +  I  + N  RYLT+SK+G + +W   +  L +  +   ++ R +DLW T    L NV K+AVSFTSKEI FYD+  K +FN Q KL  L   PI + YW+HPD   +A++++GD GG ++ + + +  SSLFER+S        + I IS  ++  G  + C   +H AH   WVR     P++
Sbjct:    8 QLESRLSTEDLMKMQNLFLPSDSSDLPVSMQRAEFVEQAWSVIGRGSQEEYGHLFDSVDVSREGWVNWERLTSYFLLGLSEKDEHIKTTAVLRWRPARTLPVPHRDRLHSITHLPNAGRYLTLSKDGTLTVWEEKNLTLLRSHRLTNDTVRPKDLWATGLVLLPNVQKIAVSFTSKEICFYDLMSK-DFNLQYKLHGLHYTPISLHYWYHPDRPDQAVLSFGDAGGQVSGVCFRSALSSLFERLS--VGGMQGSAISISWAELQQGRHRCCYTLTHTAHMGQWVRTGQSHPSI 297          
BLAST of WD repeat-containing protein 49 vs. Ensembl Cavefish
Match: si:dkey-202c14.3 (si:dkey-202c14.3 [Source:ZFIN;Acc:ZDB-GENE-121214-357])

HSP 1 Score: 159.844 bits (403), Expect = 2.831e-39
Identity = 154/637 (24.18%), Postives = 272/637 (42.70%), Query Frame = 3
Query:  222 GEEFVEALSLVLCKGTREE-----YSDLFDKIDITREGYVDWEKFASHMLLEFYEKDDRT--KSSSLPQWKELKTLSGPHKDVIQRIVLVRNLN--RYLTISKEGNVGLWGSDCKLQKVAKTHTESC----------RSRDLWVTDFAFLGNVNKVAVSFTSKEISFYDMNVKLEFNCQVKLENLFRIPICMDYWHHPDNNGEAIMAWGDTGGYINVILWSNISSSLFERVSSKASDKDENTXXXXXXXXXXXXXKTCTYFSHKAHQDWVRKVSYIPNLECFVSCATNWNTSMVICWMEKYNPSNSTSSEMAGIPESRGFSRTSCFTVHQGINSFAYNENLNLIATAGVNFQVCLWNPYVISKPNGLLRGHMASVTDVQFNKARGHLISFSKDKILRIWDVQLQVCIQRYAGVFPKGQEM-------YSKMFYHEEKLRLFITFNFGLTMLEMKPDVKDKISSHEKPLIGC-LYNSLYNQVVTACQGGIIYCWMVDTGQRVKTITEICGPQAELTCITQDSTQTRLYTGATDGNVKIWDF-NGHCYNTLIVANGNPVDISQIVILKRCVLVFGFSKSITAFWTSSFKDHKVSPS-PWKGVQTHKDDILSGASIP-PHAVATGSYDGEIIIWNINSEQ 2042
            G   +E L   L     EE       +L +++D++ EG   WEK  +++L +    +D +  K S +     ++      ++ + RIV V      RY+TISK G + +W S   LQ +     E C          R    W+TD  ++ N++KVAV+  S++I   D++       +  L  L  +   + YW++ +          D  G  +++ +                                         S K H + + ++ Y P  E  ++ + + ++S+VI  M+    S                     + + +GI  F  + +L L+ TAG++  + +WN YV S+P  +L GH  +V DV  ++    + S+SKD +L++WD+  Q C++  +  FP  Q         +  +        L I+    L++L +    ++  S+       C LY     QVVTAC    +  W V+TG++   +    G Q E+T +T D +Q RL T A++G +K+W   NG   + L   +   V    I +    +L  G+S+ +  +      D  V     WK  + H +DIL+         +ATGSYDGEII+W +++++
Sbjct:   67 GSSDLEQLRTALTAEVGEESWNSSLEELVNELDLSCEGGDGWEKLCTYVLQKSAHNEDLSEPKQSIISSDPLIRHCRHVKREPVTRIVEVSQPPPLRYITISKGGTLTVWNSS-SLQAIRSL--ELCGGAGETGGSGRQFRGWITDAVYMPNIHKVAVASMSRDIHLIDVSSSACIQ-ESHLYGLGHVATALCYWYNVE----------DICGQNSLVSYQQ---------------------------------------SPKLHSEPINRIRYEPEAELIITSSESESSSLVIVDMKHRRES-------------------YIWKIEKGILCFDISWSLGLLVTAGLDPALRIWNRYVTSRPAAVLHGHRTTVVDVVIHQTLDKIFSYSKDAVLKMWDICSQQCVKTLSLRFPNIQPACFPEQGSFPLLLSLAAAPALLISCREYLSLLRL----QNPTSNCRPSTFSCTLYIPKLKQVVTACAKSSVVVWDVNTGRKCMELNNAHG-QEEITAMTADPSQRRLITAASNGTIKVWSLQNGRPLHKLEAVSDAEV-TGVICLHDDQLLAVGWSRLVARYSIGGSHDMYVKADVSWKSGRLHSEDILAADHCAGKRLLATGSYDGEIIVWTLDTQR 625          

HSP 2 Score: 62.3882 bits (150), Expect = 3.170e-9
Identity = 43/159 (27.04%), Postives = 72/159 (45.28%), Query Frame = 3
Query: 2355 ISRLIYLESRKKIKHGGGANLISCGGNGIVRFW-------NSAEGWLIGEFVAHENASNIIMNTDVSNQYLVTGDMDGYIRVWDILSYCQTESENQKIMSPPTLISQWQSHSDEISGISFCFKFSRTLIITSSADQSAALWELNGVLIGRFGQEHRWKL 2810
            I RL++L+ R + +      L+     G + +W       N A+ ++        NA    + T+  N  L+TGD  G I+VW+I  Y   + +      PP L+  W++H + +  +          +++ S D +A LW   GV +G FGQE  W L
Sbjct:  642 IDRLLFLQKRVEDQQWRNRALLLSSQAGYICWWSICGPTHNHAKFYVPQREDERVNA----LRTNHDNSLLITGDTTGSIQVWNISQYGLYDGDEVVSEQPP-LVHTWRAHEEAVVSMEVLEHGKDLFLVSVSVDLNACLWTSCGVCVGSFGQELLWDL 795          
BLAST of WD repeat-containing protein 49 vs. Ensembl Cavefish
Match: si:dkey-202c14.3 (si:dkey-202c14.3 [Source:ZFIN;Acc:ZDB-GENE-121214-357])

HSP 1 Score: 121.709 bits (304), Expect = 1.952e-28
Identity = 87/301 (28.90%), Postives = 142/301 (47.18%), Query Frame = 3
Query: 1155 GINSFAYNENLNLIATAGVNFQVCLWNPYVISKPNGLLRGHMASVTDVQFNKARGHLISFSKDKILRIWDVQLQVCIQRYAGVFPKGQEMYSKMFYHEEKLRLFITFNFGLTMLEMKPDVKDKISSHEKPLIGCLYNSLYNQVVTACQGGIIYCWMVDTGQRVKTITEICGPQAELTCITQDSTQTRLYTGATDGNVKIWDF-NGHCYNTLIVANGNPVDISQIVILKRCVLVFGFSKSITAF--WTSSFKDHKVSPS-PWKGVQTHKDDILSGASIP-PHAVATGSYDGEIIIWNINSEQ 2042
            GI  F  + +L L+ TAG++  + +WN YV S+P  +L GH  +V DV  ++    + S+SKD +L++WD+  Q C++  +  FP  Q      F  +    L ++       L   P                        VVTAC    +  W V+TG++   +    G Q E+T +T D +Q RL T A++G +K+W   NG   + L   +   V    I +    +L  G+S+ +  +    S  +D  V     WK  + H +DIL+         +ATGSYDGEII+W +++++
Sbjct:    9 GILCFDISWSLGLLVTAGLDPALRIWNRYVTSRPAAVLHGHRTTVVDVVIHQTLDKIFSYSKDAVLKMWDICSQQCVKTLSLRFPNIQP---ACFPEQGSFPLLLS-------LAAAP------------------------VVTACAKSSVVVWDVNTGRKCMELNNAHG-QEEITAMTADPSQRRLITAASNGTIKVWSLQNGRPLHKLEAVSDAEV-TGVICLHDDQLLAVGWSRLVARYSIGGSHVRDMYVKADVSWKSGRLHSEDILAADHCAGKRLLATGSYDGEIIVWTLDTQR 273          

HSP 2 Score: 62.3882 bits (150), Expect = 2.425e-9
Identity = 43/159 (27.04%), Postives = 72/159 (45.28%), Query Frame = 3
Query: 2355 ISRLIYLESRKKIKHGGGANLISCGGNGIVRFW-------NSAEGWLIGEFVAHENASNIIMNTDVSNQYLVTGDMDGYIRVWDILSYCQTESENQKIMSPPTLISQWQSHSDEISGISFCFKFSRTLIITSSADQSAALWELNGVLIGRFGQEHRWKL 2810
            I RL++L+ R + +      L+     G + +W       N A+ ++        NA    + T+  N  L+TGD  G I+VW+I  Y   + + Q     P L+  W++H + +  +          +++ S D +A LW   GV +G FGQE  W L
Sbjct:  290 IDRLLFLQKRVEDQQWRNRALLLSSQAGYICWWSICGPTHNHAKFYVPQREDERVNA----LRTNHDNSLLITGDTTGSIQVWNISQYGLYDGDEQ-----PPLVHTWRAHEEAVVSMEVLEHGKDLFLVSVSVDLNACLWTSCGVCVGSFGQELLWDL 439          
BLAST of WD repeat-containing protein 49 vs. Ensembl Cavefish
Match: wdr5 (WD repeat domain 5 [Source:NCBI gene;Acc:103033424])

HSP 1 Score: 58.151 bits (139), Expect = 2.951e-8
Identity = 44/212 (20.75%), Postives = 95/212 (44.81%), Query Frame = 3
Query: 1152 QGINSFAYNENLNLIATAGVNFQVCLWNPYVISKPNGLLRGHMASVTDVQFNKARGHLISFSKDKILRIWDVQLQVCIQRYAGVFPKGQEMYSKMFYHEEKLRLFITFNFGLTMLEMKPDVKDK-ISSHEKPLIGCLYNSLYNQVVTACQGGIIYCWMVDTGQRVKTITEICGPQAELTCITQDSTQTRLYTGATDGNVKIWDFN-GHCYNT 1781
            + ++S  ++ +   +A++  +  + +W  Y   K    + GH   ++DV ++     L+S S DK L+IWDV    C++   G       ++   F  +  L +  +F+  + + ++K     K + +H  P+    +N   + +V++   G+   W   +GQ +KT+ +   P       + +     +     D  +K+WD++ G C  T
Sbjct:   46 KAVSSVKFSPSGEWLASSSADKLIKIWGAY-DGKFEKTISGHKLGISDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKG---HSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNG--KYILAATLDNTLKLWDYSKGKCLKT 251          
BLAST of WD repeat-containing protein 49 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000005521.1 (pep scaffold:Pmarinus_7.0:GL477585:56150:70911:-1 gene:ENSPMAG00000005018.1 transcript:ENSPMAT00000005521.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 147.132 bits (370), Expect = 1.888e-37
Identity = 93/317 (29.34%), Postives = 155/317 (48.90%), Query Frame = 3
Query: 1188 NLIATAGVNFQVCLWNPYVISKPNGLLRGHMASVTDVQFNKARGHLISFSKDKILRIWDVQLQVCIQRYAGVFPKGQEMYSKMFYHEEKLRLFITFNFGLTMLEMKPDV---KDKISSHEKPLIGCLYNSLYNQVVTACQGGIIYCWMVDTGQRVKTITEICGPQAE--LTCITQDSTQTRLYTGATDGNVKIWDF-NGHCYNTLIVANGNP--VDISQIVILK-RCVLVFGFSKSITAFWTSSFKDHKVS-PSP-WKG--VQTHKDDILSGASIPPHAVATGSYDGEIIIWNINSEQASRTM----TQRSQDEMKE 2087
            +L+ T G++  V LWNPYV  +P G+LRGH + +  +   +    + S   D+ +++WD Q Q C+   +      +   S   Y      L +    G+ +L ++  +       +SH +P+  C Y++ + QVV+  +  ++  W +D+G       E CG   E  +TC+  DS+  RL TG  DG +K+W++ NG C  TL          D + +V+ K + ++  G+ K I  F  S      +  P P W     + H++D+L  A  PP  +AT SYDGE+I+WN+ S   S  +     QRS D  ++
Sbjct:   12 SLVVTGGMDRTVRLWNPYVPGRPTGVLRGHTSPICYLSICEETSRIFSVGSDRNVKVWDAQEQTCLCSVSPKMSGLRGEVSACHYLPAARALCVATEGGVALLSVRDGLHMDAGAATSHREPVRCCRYSAEFRQVVSCSEDSVVKLWDLDSGL---PTFEFCGAHGESAITCMAFDSSGRRLITGGRDGCLKVWNYNNGQCLRTLRKQRNAEEICDCTYVVVNKNKYIISVGWDKRINIFLDSQEDQQLIQFPQPHWADDLRKGHREDVLCVAQCPPSLLATSSYDGEVIVWNLVSGHVSCRLPPPPAQRSADPAED 325          

HSP 2 Score: 77.7962 bits (190), Expect = 7.354e-15
Identity = 44/156 (28.21%), Postives = 78/156 (50.00%), Query Frame = 3
Query: 2349 FNISRLIYLESRKKIKHGGGANLISCGGNGIVRFWNSAEGW-LIGEFVAHENASNII-MNTDVSNQYLVTGDMDGYIRVWDILSYCQTESENQKIMSPPTLISQWQSHSDEISGISFCFKFSRTLIITSSADQSAALWELNGVLIGRFGQEHRWKL 2810
             ++S++I+L+SR   K    A L++ G  G + FWN   G  L   F A      +  + + + +  L+  D  G++  WD+ SY     E +    PP L+S W++H   I+ +    +    L++T++ D S  LW ++G  +G FGQ+  W +
Sbjct:  328 LSVSKVIFLKSRVAHKDRA-ALLVASGPRGFIHFWNVYHGGRLFARFPAGRQGRPVCCLASALGDSVLLAADQTGHVYAWDVSSYAMQGPEEE----PPQLVSLWRAHVSAITSMDVIEEHK--LLLTAALDCSVRLWSVDGAFVGTFGQDTLWDI 476          
BLAST of WD repeat-containing protein 49 vs. Ensembl Sea Lamprey
Match: WDR86 (WD repeat domain 86 [Source:HGNC Symbol;Acc:HGNC:28020])

HSP 1 Score: 63.929 bits (154), Expect = 7.727e-11
Identity = 53/225 (23.56%), Postives = 88/225 (39.11%), Query Frame = 3
Query: 1155 GINSFAYNENLN-LIATAGVNFQVCLWNPYVISKPNG-----LLRGHMASVTDVQFNKARGHLISFSKDKILRIWDVQLQVCIQRYAG-------VFPKGQEMYSKMFYHEEK---------LRLFITFNFGLTMLEMKPDVKDKISSHEKPLIGCLYNSLYNQVVTACQGGIIYCWMVDTGQRVKTITEICGPQAELTCITQDSTQTRLYTGATDGNVKIWDFN 1763
            G+N  +  E+ + L+ T G +    LW+      P G      LRGH   +T            + S D+  R WDVQ   C+Q Y G       V P    ++S  +    +         LR+F      +  L +    K +  S    L     N+    +++    G +  W + +G   +T+    G Q  + C+  D++   LY+G  DG V+ WD +
Sbjct:   15 GVNCMSAGEDGSALLLTGGEDGSAALWDA---EAPQGQGRRATLRGHEGYITHCALAADGARAFTCSADRTARCWDVQSGHCLQVYRGHAGVVNRVVPHAGWLFSSSYDKTARCWDTRTGDALRVFAGHRSCVLPLALYCPPKGERRSSSAALAALEENTTL-LLMSGSVDGTVRLWRLSSGACARTLR---GHQGPVLCLAVDASNGALYSGGADGTVRKWDLS 232          
BLAST of WD repeat-containing protein 49 vs. Ensembl Sea Lamprey
Match: snrnp40 (small nuclear ribonucleoprotein 40 (U5) [Source:ZFIN;Acc:ZDB-GENE-040426-978])

HSP 1 Score: 51.6026 bits (122), Expect = 6.465e-7
Identity = 54/252 (21.43%), Postives = 103/252 (40.87%), Query Frame = 3
Query: 1140 FTVHQG-INSFAYNENLNLIATAGVNFQVCLWNPYVISKPNGLLRGHMASVTDVQFNKARGHLISFSKDKILRIWDVQLQVCIQRYAG-------VFP--KGQEMYSKMFYHEEKLRLFITFNFGLTMLEMKPDVKDKISSHE-KPLIGCL---YNSLYNQVVTACQGGIIYCWMVDTGQRVKTITEICGPQAELTCITQDSTQTRLYTGATDGNVKIWDFNGHCYNTLIVANGNPVDISQIVILKRCVLVF 1853
             T H+G +    ++ N N +A+AG +  + +WN Y        L+GH  ++ D+ ++     + + S DK + +WD +    I+R  G        FP  +G +M       +  ++L+              D + K S H  +    CL   +N   +Q+++     +I  W +   ++ K I  + G    +T ++     + L + A D +V+IW                  DI     ++RCV +F
Sbjct:   53 LTGHEGEVYCCKFHPNGNTLASAGFDRTILMWNVYGDCDNYAHLKGHTGAILDIHYSTDGSTIFTSSTDKTVGLWDSETGERIKRLKGHTSFVNACFPARRGPQMVCTA-SDDGTVKLW--------------DTRKKGSVHSFQNTYQCLSVTFNDTSDQILSGGIDNVIKVWDL---RQNKLIYTMKGHNDSVTGLSLSPDGSYLLSNAMDNSVRIW------------------DIRPFAPMERCVKIF 268          
BLAST of WD repeat-containing protein 49 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008862.1 (pep scaffold:Pmarinus_7.0:GL476579:86637:114999:1 gene:ENSPMAG00000008000.1 transcript:ENSPMAT00000008862.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 52.373 bits (124), Expect = 6.571e-7
Identity = 30/119 (25.21%), Postives = 59/119 (49.58%), Query Frame = 3
Query: 2406 GANLISCGGNGIVRFWNSAEGWLIGEFVAHENASNIIMNTDVSNQYLVTGDMDGYIRVWDILSYCQTESENQKIMSPPTLISQWQSHSDEISGISFCFKFSRTLIITSSADQSAALWEL 2762
            G +++S   +  +R W++  G  +   V H++ ++     ++ +  LV+G+ D  +++WDI    +T    Q +  P         H   ++    C +FSR L++TSS D +  LW+L
Sbjct:  404 GVHIVSGSLDTSIRVWDAETGTCLHTLVGHQSLTS---GMELRDNILVSGNADSTVKIWDI----KTGQCLQTLQGP-------NKHQSAVT----CLQFSRKLVVTSSDDGTVKLWDL 504          
BLAST of WD repeat-containing protein 49 vs. Ensembl Nematostella
Match: EDO44327 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RW01])

HSP 1 Score: 595.89 bits (1535), Expect = 0.000e+0
Identity = 299/647 (46.21%), Postives = 411/647 (63.52%), Query Frame = 3
Query:  129 KLELKLNIKDLETLQEAFFMDGS-HNRSQHFNGEEFVEALSLVLCKGTREEYSDLFDKIDITREGYVDWEKFASHMLLEFYEKDDRTKSSSLPQWKELKTLSGPHKDVIQRIVLVRNLNRYLTISKEGNVGLWGSDCKLQKVAKTHTES--CRSRDLWVTDFAFLGNVNKVAVSFTSKEISFYDMNVKLEFNCQVKLENLFRIPICMDYWHHPDNNGEAIMAWGDTGGYINVILWSNISSSLFERVSSKASDKDENTXXXXXXXXXXXXXKTCTYFSHKAHQDWVRKVSYIPNLECFVSCATNWNTSMVICWMEKYNPSNSTSSEMAGIPESRGFSRTSCFTVHQGINSFAYNENLNLIATAGVNFQVCLWNPYVISKPNGLLRGHMASVTDVQFNKARGHLISFSKDKILRIWDVQLQVCIQRYAGVFPKG-QEMYSKMFYHEEKLRLFITFNFGLTMLEMKPDVKDKISSHEKPLIGCLYNSLYNQVVTACQGGIIYCWMVDTGQRVKTITEICGPQAELTCITQDSTQTRLYTGATDGNVKIWDFNGHCYNTLIVANGNPVDISQIVILKRCVLVFGFSKSITAFWTSSFKDHKVSPSPWKGVQTHKDDILSGASIPPHAVATGSYDGEIIIWNINSEQASRTM 2057
            KL  +L + DL+ +Q+AF ++ S   R    + ++F E LS+VL KG REEY +LF+KID+ +EG+VDW+KF+SHMLLE+YEKDDR K++ +PQW+EL+ +S PHK+VI+RI  + N +RYL++SKEG + LW    K  +  +   +    + RDLWVTDF  + N+ K+A++ TSKEI+ YD++ K EFNCQ +++NL   P+C+DY + PD   EAI+A+GD  G +N +L+S ++ +LF+R +  A  K                                 +V Y  +L+CF+SC+T++  S+V+ W+EK      T S M          RT+ F + QG+N+F YNE  NL+ATAGVN  VCLWNPYVISKP G+LRGHM SV  V F ++RG LIS SKDK+LRIWD  LQVC+QR +G+FPKG  E+   MFY EE  +LF  FN  LT++ MKP+VKD++ SHE+P+   +YNS +NQVVTAC G +I  WM+DTGQ+VK      G  AE+T ITQD+T+TRL+T + DG VKIWDFNGHC++ L+  NG+P +IS                                       Q H+DDILS A  PP  +A+ SYDGEI+IWN+NSEQASR +
Sbjct:   40 KLVSRLTMHDLKAIQDAFTINQSGQQRELSLDVDQFCEILSIVLNKGVREEYEELFNKIDVAKEGFVDWDKFSSHMLLEYYEKDDRMKTTQVPQWRELRNISSPHKEVIRRISPLINPSRYLSVSKEGILCLWSLGMKQLRTVQVQPDQDEVKQRDLWVTDFIPMQNLYKLAIALTSKEIAIYDLSSKSEFNCQFRIKNLDDTPLCLDYCN-PDKPNEAILAFGDVSGQVNALLFSAVNIALFDRPAQPAGSK---------------------------------QVMYSAHLDCFISCSTSYKGSLVLGWIEK------TKSNM----------RTTAFKIPQGVNAFDYNEKANLVATAGVNHHVCLWNPYVISKPVGVLRGHMQSVVAVHFIESRGQLISLSKDKVLRIWDTHLQVCLQRLSGMFPKGPAEVSITMFYDEEHSKLFTAFNQQLTLMVMKPEVKDRVMSHEQPVTAAIYNSKFNQVVTACAGSVITMWMIDTGQKVKQFANAHG-NAEITTITQDATETRLFTASADGTVKIWDFNGHCHSILMAGNGDPAEIS---------------------------------------QEHQDDILSVAYSPPTTIASASYDGEIVIWNMNSEQASRHL 596          

HSP 2 Score: 245.358 bits (625), Expect = 7.703e-67
Identity = 136/327 (41.59%), Postives = 194/327 (59.33%), Query Frame = 3
Query: 2340 DVMFNISRLIYLESRKKIKHGGGANLISCGGNGIVRFWNSAEGWLIGEFVAHENASNIIMNTDVSNQYLVTGDMDGYIRVWDILSYCQTESENQKIMSPPTLISQWQSHSDEISGISFCFKFSRTLIITSSADQSAALWELNGVLIGRFGQEHRWKLGSXXXXXXXXXXXXHEDEVVKQEEDKYKVDPNWYPDPEAIQNPS---GYRINTWKDTNLGKDYQELRVRKRERIQPSSIPDLPYLYGEKIGRPTFGPFYSLNISSFEEIEDIEQPEFMEYPEKFFNETEEFLTKTARVPLL---NETLKAVFDERSLLPEYILEFEHKFR 3302
            D+   +++LI+L SR       GANL+SC G+GIVRFWNS +   + EF+AH++A ++ M  D +N YLVTGD DG I+VWDI  YC  E +N  I  PP L+ Q+Q H+D I+ I    +  R L++T+S+D SAALW++ G  IG FGQE  WK+  I E    A  +  E+E   +EE +   D       +   N      YR++TW  T LGK Y E R  KRER QP SIPDLPYL  EK G+   GP+ +L  +   ++  I +P+F+ +PEK+F+E +    ++  +P L    E L+  +D++SL P+ ILE E K +
Sbjct:  618 DIGSAVTKLIFLNSRPLPTSSPGANLVSCCGSGIVRFWNSQKHAFLAEFLAHQHAGSLTMAVDGTNSYLVTGDADGLIKVWDISEYCVEEPDN-TITQPPPLLKQFQPHTDIINHIGLLTRNERLLVLTASSDCSAALWDIEGRQIGVFGQEEHWKIEPISEEERKAEQQRLEEEEESEEELEQNQDAEETGQADYFNNEDFDPEYRMSTWDRTILGKAYMETRSEKRERRQPMSIPDLPYLNWEKTGQAPAGPYAALETAELADVGTISKPDFVSHPEKYFSERQSAGKRSKALPPLPSITERLQMRYDDKSLFPKSILEMEAKMK 943          
BLAST of WD repeat-containing protein 49 vs. Ensembl Nematostella
Match: EDO38627 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SCA8])

HSP 1 Score: 259.61 bits (662), Expect = 1.955e-73
Identity = 186/625 (29.76%), Postives = 311/625 (49.76%), Query Frame = 3
Query:  273 EEYSDLFDKIDITREGYVDWEKFASHMLLEFYEKDD---RTKSSSLPQWKELKTLSGPHKDVIQRIVLVRNLNRYLTISKEGNVGLWGSDCKLQKVAKTHTESCRSRDLWVTDFAFLGNVNKVAVSFTSKEISFYDMNVKLEFNCQVKLENLFRIPICMDYWHHPDNNGEAIMAWGDTGGYINVILWSNISSSL--------FERVSSKASDKDENTXXXXXXXXXXXXXKTCTYFSHKAHQDWVRKVSYIPNLECFVSCATNWNTSMVI------CWMEKYNPSNSTSS-----EMAGI-----PESRGFSRTSCFTVHQGINSFAYNENLNLIATAGVNFQVCLWNPYVISKPNGLLRGHMASVTDVQFNKARGHLISFSKDKILRIWDVQLQVCIQRYAGVFPKGQEM---YSKMFYHEEKLRLFITFN--FGLTMLEMKPDVKDKISSHEKPLIGCLYNSLYNQVVTACQGGIIYCWMVDTGQRVKTITEICGPQAELTCITQDSTQTRLYTGATDGNVKIWDF-NGHCYNTLIVAN--GNPVDISQIVILK-RCVLVFGFSKSITAFWTSSFKDHKVSPS--PWKG--VQTHKDDILSGASIPPHAVATGSYDGEIIIWN 2027
            ++ + LF KID + +G ++W++F + M LE+ EK++   R+K +S  Q   L   S   + VI+  V   + N +L +S++G V  W  + + +++   H ES   +  W+TD+  + + NK  +S   +EI F++++   E  CQ+    L   P+ +DY     +  E I+ +GD+ G +N+ +  +   +L         E ++S   D   N+             +   +   K H DWV ++ Y  +L   +SC+ +  T++VI        +E     N+TS       +A +     P  R  S  + F V++G+ +F + +  NLI T G++  V +WNPYV SKP G+LRGH A +  +        + S S DK +++WD+  Q C+     V PK  ++    S + Y+     L +  +    L  L+ KP  +D  ++H++ +    YN  +  VVTA +G +   W V+TG  V    ++ G  A +TC+  DST+ RL +G  DG ++IW++ NGHC  TL          D++ IV+ K R ++  G+ + I  F   +   H V      W    +  HK+DILS A  PP+ +AT SYDGEIIIWN
Sbjct:   33 DQMTALFMKIDSSSDGEINWDEFCTFMQLEYAEKEESYFRSKETSF-QLPALTENSSQREQVIR--VCHTSDNNFLVVSQDGLVSFWSQNLEFKRMK--HIESSSKKTKWITDYVLMPHFNKFIISTGDREIQFFELST-FEPYCQIS--GLETTPLRVDYC--SPSTDECIIIYGDSQGCVNIFIMHSTGETLRNWKKMPKVEGIASVNIDSVVNS-------------ENTKFIRWKVHNDWVAQLKYYDSLRAVISCSNHQETALVIGQTTGSTHIEAQLRENTTSQGERKKNVAAVVRDNQPRRRLDSDQTVFRVYKGVKTFDFCKEKNLIVTGGMDRLVRMWNPYVPSKPTGILRGHTAPIFHLFIVAEDDRIFSISTDKTVKVWDLHDQSCL---LTVRPKAHKIRGDVSAIHYNPSSRGLAVATSDQVALLPLKTKPSARDMTTTHKEAVTCLKYNKSFKHVVTASEGSVCRVWDVETGHAVFEFNQLHGDTA-ITCMAFDSTERRLISGGRDGRLRIWNYNNGHCIRTLEKEKDIDEVTDLTYIVMHKNRYIISVGWDRRINVFSDDTDDFHHVQRPYIDWSDDLLNGHKEDILSVAVCPPNLLATSSYDGEIIIWN 630          
BLAST of WD repeat-containing protein 49 vs. Ensembl Nematostella
Match: EDO36438 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SIN2])

HSP 1 Score: 187.578 bits (475), Expect = 2.956e-48
Identity = 162/626 (25.88%), Postives = 284/626 (45.37%), Query Frame = 3
Query:   99 KESHTPLTENKLELKLNIKDLETLQEAFFMDGSHNRSQH--------FNG-EEFVEAL-SLVLCKGTREEYSDLFDKIDITREGYVDWEKF-----ASHMLLEFYEKDDRTKSSSLPQWKELKTLSGPHK--DVIQRIVLVRNLNRYLTISKEGNVGLWGSDCKLQKVAKTHTESCRSRDLWVTDFAFLGNVNKVAVSFTSKEISFYDMNVKLEFNCQVKLENLFRIPICMDY--WHHPDNNGEAIMAWGDTGGYINVILWSNISSSLFERVSSKASDKDENTXXXXXXXXXXXXXKTCTYFSHKAHQDWVRKVSYIPNLECFVSCATNWNTSMVICWMEKYNPSNSTSSEMAGIPESRGFSRTSCFTVHQGINSFAYNENLNLIATAGVNFQVCLWNPYVISKPNGLLRGHMASVTDVQFNKARGHLISFSKDKILRIWDVQLQVCIQRYAGVFPK-GQEMYSKMFYHEEKLRLFITFNFGLTMLEMKP---DVKDKIS---SHEKPLIGCLYNSLYNQVVTACQGGIIYCWMVDTGQRVKTITEICGPQAELTCITQDSTQTRLYTGATDGNVKIWDF-NGHCYNTLIVANGNPVDISQIVIL-------KRCVLVFGFSKSIT 1874
            + S  P T      KL + D + ++E  ++D   N  +          NG E F EA+ +L     + ++   LF KI +  +  VDW +       +  + +    +D +   +  + K +    G  K  D++Q I+ V   + Y+T S++G +  W           ++ ES      WVT   FL ++ ++A + + + I+ +D   K + +   +++ +   P CM    W     N + I+ +GD  GY+N++    ISS      +S A  K ++ ++    + +   IK   +F      DWV K+ Y P LE F  C+                P +S S  + G+             V +G+N F Y    N+I TAG +  V +W+P + ++P G L GH+ ++ ++  N+    LIS S  ++ R+WD+Q   C+Q +     + G++  S M +  +  RL      G ++++  P    ++D +    +H++P+   LYN   NQV++ C  G++  W ++TGQ V  +T+  G   E+T +  D+T  RL TGA DG++K WDF +G  Y             + I  L       KRCVLV  + + IT
Sbjct:    5 QNSSRPYTSGSFRTKLELFD-KFIKEFTYVDEELNPEERRQILQDRLTNGYEPFCEAIRNLFGNDVSTQDLKALFRKIALNPDAKVDWSELFGIGGPTDEVPDLLLNEDTSSVLTTSKRKTVAEAGGDKKRRDIVQSILHVPKYDFYITASQKGIICQW-----------SNKESS-----WVTGCGFLPSLRRIAAT-SERAIALWDYRAKRKQSTIYQIKPMENSPQCMTCIPWKANSMNEDTIL-FGDDQGYVNIL---TISSKDLHMKNSSA--KGDSAVVTIEPNKLSSEIKRRKFF-----DDWVLKIKYFPQLEMFGCCS----------------PGSSCSFILGGVDRVLNNGPVRELGVPKGVNCFDYCTRANVIVTAGADKIVRIWHPLIFTRPTGKLLGHLFTIVEIAVNEKDQQLISLSTARVFRVWDLQTLTCLQVFTDNEERPGEKRISAMLFDAKHDRLIT----GCSVIDTWPLTRAIQDSLQVPHTHDRPISQLLYNPQMNQVISVCTEGVMKVWEMETGQMVYQVTDAHGTSNEVTAMNVDNTGYRLITGAYDGSIKAWDFGSGQLYKKYPDEPAKKRQENTITGLVYHTVDNKRCVLVSSWGQGIT 581          

HSP 2 Score: 52.7582 bits (125), Expect = 1.130e-6
Identity = 41/141 (29.08%), Postives = 64/141 (45.39%), Query Frame = 3
Query: 2415 LISCGGNGIVRFWNSAEGWLIGEF--VAHENASNII-MNTDVSNQYLVTGDMDGYIRVWDILSYCQTESENQKIMSPPTLISQ---WQSHSDEISGISFCFKFSRTLIITSSADQSAALWELN-GVLIGRFGQEHRWKLGS 2816
            L+S   +G +RFW +  G L+ E   V    AS +  + TD   +++++GD  GY+ VWD                   +I Q   W++H   + G+      S   ++T+S D S  +W  + G  IG FGQ   W L S
Sbjct:  787 LVSAHHDGYLRFW-TLSGRLLTEIRAVTRRQASAVTSLCTDADCRHVISGDAKGYVTVWD------------------NVIKQVVCWRAHLTRVVGVEHV--DSADAVVTASTDLSVRVWYRDTGHFIGFFGQPRLWHLPS 906          
BLAST of WD repeat-containing protein 49 vs. Ensembl Nematostella
Match: EDO38984 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SBD4])

HSP 1 Score: 115.931 bits (289), Expect = 4.500e-28
Identity = 79/259 (30.50%), Postives = 128/259 (49.42%), Query Frame = 3
Query:  129 KLELKLNIKDLETLQEAFFMDGSHNRSQHFNGEEFVEALSLVL-CKGTRE--EYSDLFDKIDITREGYVDWEKFASHMLLEFYEKDDRTKSSSLPQWKE-LKTLSGPHKDVIQRIVLV------------RNLNRYLTISKEGNVGLWGSDCKLQKV--AKTHTESCRSRDLWVTDFAFLGNVNKVAVSFTSKEISFYDMNVKLEFNCQVKLENLFRIPICMDYWHHPDNNGEAIMAWGDTGGYINVILWSNISSSLFE 851
            +LE ++N + LE LQ   F +   +     + EEF  A+   + CK   +  + +  F K+D   +G VDWE+F S+MLLE   KD  T      ++    + +   H+D I RI                N+ RY+T+S+EG +  W  D    +       +E   S+ +W+TD   L N  K+AVS   +EI+FYD +       Q  L  L    +CMDYW+ P +  ++I+ +GD+GG ++ I +S ++  LF+
Sbjct:   50 RLEDQMNNEHLEVLQR-IFEEADEDGGGGLDYEEFRRAMIKTMSCKEVPDDNQLAITFMKVDANCDGTVDWEEFCSYMLLENQLKDVMTSDEREMEFPHPAREIPSAHRDNIARITYFAKMSHGPDESGDNNVGRYVTVSREGVLHFWSMDLNPIRTITVSNASEGKASKSVWITDCVVLPNAKKIAVSSADREIAFYDCSAN-SVEKQFVLSGLENCALCMDYWYDPRHPNQSILLFGDSGGKVSCIKFSAVNLGLFD 306          
BLAST of WD repeat-containing protein 49 vs. Ensembl Nematostella
Match: EDO30964 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SZA2])

HSP 1 Score: 98.2117 bits (243), Expect = 5.055e-23
Identity = 63/215 (29.30%), Postives = 104/215 (48.37%), Query Frame = 3
Query:  960 HQDWVRKVSYIPNLECFVSCATNWNTSMVICWMEKYNPSNSTSSEMAGIPESRGFSRTSCFTVHQGINSFAYNENLNLIATAGVNFQVCLWNPYVISKPNGLLRGHMASVTDVQFNKARGHLISFSKDKILRIWDVQLQVCIQRYAGVFPKGQEMYSKMFYHEEKLR-----LFITFNFGLTMLEMK--PDVKDKISSHEKPLIGCLYNSLYNQV 1583
            H     +V YIP  E  +SC+ + + S+V+  ++                      +T  F V +G++ F Y+ +LN+I T GV+  V +WNPYV SKP  +++GH +S+ D+  +     + S+ K+ +L+ W+V+ QVCIQ  A   P G  +     +    +R     L IT N  L  +++      K   ++H KPL   +YN    QV
Sbjct:   15 HSYLFPRVQYIPVKEFVISCSCSSHDSLVVRDVDDKK------------------RKTYVFKVAKGVDCFDYSHSLNVIITGGVDHAVRVWNPYVTSKPVAIMKGHSSSIVDLVIHPGLEQVFSYDKEGVLKCWNVKEQVCIQTLAIRDPFGHRVPEHGPFPFRLIRSPVSSLLITSNDSLIEIKLVGLGSTKSLKTTHAKPLCAAIYNPEVKQV 211          
BLAST of WD repeat-containing protein 49 vs. Ensembl Medaka
Match: ENSORLT00000015414.2 (WD repeat-containing protein 64 [Source:NCBI gene;Acc:101165086])

HSP 1 Score: 310.457 bits (794), Expect = 2.715e-93
Identity = 175/474 (36.92%), Postives = 269/474 (56.75%), Query Frame = 3
Query:  111 TPLTENKLELKLNIKDLETLQEAFFMDGSHNRSQHFNGEEFVEALSLVLCKGTREEYSDLFDKIDIT--------------REGYVDWEKFASHMLLEFYEKDDRTKSSSLPQWKELKTLSGPHKDVIQRIVLVRNLNRYLTISKEGNVGLWGS-DCKLQKVAKTHTESCRSRDLWVTDFAFLGNVNKVAVSFTSKEISFYDMNVKLEFNCQVKLENLFRIPICMDYWHHPDNNGEAIMAWGDTGGYINVILWSNISSSLFERVSSKASDKDENTXXXXXXXXXXXXXKTCTYF-SHKAHQD-WVRKVSYIPNLECFVSCATNWNTSMVICWMEKYNPSNSTSSEMAGIPESRGFSRTSCFTVHQGINSFAYNENLNLIATAGVNFQVCLWNPYVISKPNGLLRGHMASVTDVQFNKARGHLISFSKDKILRIWDVQLQVCIQRYAGVFPKGQE-MYSKMFYHEEKLRLFITFN 1478
            T +   +LE ++N KD   LQ + F+D S  + +  +  EF+        +G+++EY  LFD + +T              +EG+VDW    S +L E + K ++TK  ++P WK  +TL+ PH+D +Q+++ +++ ++YLT+SK G V LW   D  +    +    +  SRDLWVTD   L NV K+AVSFT +E+ FYD+  K +F C+ KL+ L   P C+DYW  P +  +A++  GDTGG ++ + +++  +SLFE   S+    D ++  +   D +     +C    +HKAH   WVRKV Y+ +L  F SC+T   +SMVI W +                E  G  R + +   +G+    Y+   NLIATAG++ QV LWNPYV S+P   L GH+  VT V+F + +  L+SFSKDK+L +WDV  Q+C+QR AGVFPK QE  ++ +F  EE+  L ++FN
Sbjct:    3 TAVEVGQLESRMNAKDYMHLQ-SIFVDCS-GKPRSLSRTEFIHLAWRSADRGSKQEYGLLFDSVVVTQKSSSLLHSSDEVKKEGHVDWGALCSFLLEETWRKLNQTKDFNVPLWKPRRTLTCPHRDSVQKVLYLQSSDQYLTVSKGGKVVLWQEVDLSVLSTCRLQNSTVASRDLWVTDVVLLQNVQKIAVSFTCEEVCFYDLRSKQDFPCKYKLQGLRFAPWCLDYWMDPCDADQAVLTIGDTGGQVSALHFTSAQTSLFE---SRCLQLDSDSAKVVSWDQLVKGRHSCCRMETHKAHAPAWVRKVLYLSSLRAFASCSTRPQSSMVIGWRD----------------EGAGKMRITSYVTRKGVWDIDYHRQWNLIATAGLDDQVLLWNPYVTSEPVCALAGHLNEVTAVRFMQTKDQLLSFSKDKVLCLWDVSSQLCVQRVAGVFPKVQEDTHTLLFLREERQHLLLSFN 455          
BLAST of WD repeat-containing protein 49 vs. Ensembl Medaka
Match: ENSORLT00000043076.1 (WD repeat-containing protein 64 [Source:NCBI gene;Acc:101165086])

HSP 1 Score: 310.457 bits (794), Expect = 2.715e-93
Identity = 175/474 (36.92%), Postives = 269/474 (56.75%), Query Frame = 3
Query:  111 TPLTENKLELKLNIKDLETLQEAFFMDGSHNRSQHFNGEEFVEALSLVLCKGTREEYSDLFDKIDIT--------------REGYVDWEKFASHMLLEFYEKDDRTKSSSLPQWKELKTLSGPHKDVIQRIVLVRNLNRYLTISKEGNVGLWGS-DCKLQKVAKTHTESCRSRDLWVTDFAFLGNVNKVAVSFTSKEISFYDMNVKLEFNCQVKLENLFRIPICMDYWHHPDNNGEAIMAWGDTGGYINVILWSNISSSLFERVSSKASDKDENTXXXXXXXXXXXXXKTCTYF-SHKAHQD-WVRKVSYIPNLECFVSCATNWNTSMVICWMEKYNPSNSTSSEMAGIPESRGFSRTSCFTVHQGINSFAYNENLNLIATAGVNFQVCLWNPYVISKPNGLLRGHMASVTDVQFNKARGHLISFSKDKILRIWDVQLQVCIQRYAGVFPKGQE-MYSKMFYHEEKLRLFITFN 1478
            T +   +LE ++N KD   LQ + F+D S  + +  +  EF+        +G+++EY  LFD + +T              +EG+VDW    S +L E + K ++TK  ++P WK  +TL+ PH+D +Q+++ +++ ++YLT+SK G V LW   D  +    +    +  SRDLWVTD   L NV K+AVSFT +E+ FYD+  K +F C+ KL+ L   P C+DYW  P +  +A++  GDTGG ++ + +++  +SLFE   S+    D ++  +   D +     +C    +HKAH   WVRKV Y+ +L  F SC+T   +SMVI W +                E  G  R + +   +G+    Y+   NLIATAG++ QV LWNPYV S+P   L GH+  VT V+F + +  L+SFSKDK+L +WDV  Q+C+QR AGVFPK QE  ++ +F  EE+  L ++FN
Sbjct:    3 TAVEVGQLESRMNAKDYMHLQ-SIFVDCS-GKPRSLSRTEFIHLAWRSADRGSKQEYGLLFDSVVVTQKSSSLLHSSDEVKKEGHVDWGALCSFLLEETWRKLNQTKDFNVPLWKPRRTLTCPHRDSVQKVLYLQSSDQYLTVSKGGKVVLWQEVDLSVLSTCRLQNSTVASRDLWVTDVVLLQNVQKIAVSFTCEEVCFYDLRSKQDFPCKYKLQGLRFAPWCLDYWMDPCDADQAVLTIGDTGGQVSALHFTSAQTSLFE---SRCLQLDSDSAKVVSWDQLVKGRHSCCRMETHKAHAPAWVRKVLYLSSLRAFASCSTRPQSSMVIGWRD----------------EGAGKMRITSYVTRKGVWDIDYHRQWNLIATAGLDDQVLLWNPYVTSEPVCALAGHLNEVTAVRFMQTKDQLLSFSKDKVLCLWDVSSQLCVQRVAGVFPKVQEDTHTLLFLREERQHLLLSFN 455          
BLAST of WD repeat-containing protein 49 vs. Ensembl Medaka
Match: ENSORLT00000037247.1 (WD repeat-containing protein 64 [Source:NCBI gene;Acc:101165086])

HSP 1 Score: 310.457 bits (794), Expect = 2.715e-93
Identity = 175/474 (36.92%), Postives = 269/474 (56.75%), Query Frame = 3
Query:  111 TPLTENKLELKLNIKDLETLQEAFFMDGSHNRSQHFNGEEFVEALSLVLCKGTREEYSDLFDKIDIT--------------REGYVDWEKFASHMLLEFYEKDDRTKSSSLPQWKELKTLSGPHKDVIQRIVLVRNLNRYLTISKEGNVGLWGS-DCKLQKVAKTHTESCRSRDLWVTDFAFLGNVNKVAVSFTSKEISFYDMNVKLEFNCQVKLENLFRIPICMDYWHHPDNNGEAIMAWGDTGGYINVILWSNISSSLFERVSSKASDKDENTXXXXXXXXXXXXXKTCTYF-SHKAHQD-WVRKVSYIPNLECFVSCATNWNTSMVICWMEKYNPSNSTSSEMAGIPESRGFSRTSCFTVHQGINSFAYNENLNLIATAGVNFQVCLWNPYVISKPNGLLRGHMASVTDVQFNKARGHLISFSKDKILRIWDVQLQVCIQRYAGVFPKGQE-MYSKMFYHEEKLRLFITFN 1478
            T +   +LE ++N KD   LQ + F+D S  + +  +  EF+        +G+++EY  LFD + +T              +EG+VDW    S +L E + K ++TK  ++P WK  +TL+ PH+D +Q+++ +++ ++YLT+SK G V LW   D  +    +    +  SRDLWVTD   L NV K+AVSFT +E+ FYD+  K +F C+ KL+ L   P C+DYW  P +  +A++  GDTGG ++ + +++  +SLFE   S+    D ++  +   D +     +C    +HKAH   WVRKV Y+ +L  F SC+T   +SMVI W +                E  G  R + +   +G+    Y+   NLIATAG++ QV LWNPYV S+P   L GH+  VT V+F + +  L+SFSKDK+L +WDV  Q+C+QR AGVFPK QE  ++ +F  EE+  L ++FN
Sbjct:    3 TAVEVGQLESRMNAKDYMHLQ-SIFVDCS-GKPRSLSRTEFIHLAWRSADRGSKQEYGLLFDSVVVTQKSSSLLHSSDEVKKEGHVDWGALCSFLLEETWRKLNQTKDFNVPLWKPRRTLTCPHRDSVQKVLYLQSSDQYLTVSKGGKVVLWQEVDLSVLSTCRLQNSTVASRDLWVTDVVLLQNVQKIAVSFTCEEVCFYDLRSKQDFPCKYKLQGLRFAPWCLDYWMDPCDADQAVLTIGDTGGQVSALHFTSAQTSLFE---SRCLQLDSDSAKVVSWDQLVKGRHSCCRMETHKAHAPAWVRKVLYLSSLRAFASCSTRPQSSMVIGWRD----------------EGAGKMRITSYVTRKGVWDIDYHRQWNLIATAGLDDQVLLWNPYVTSEPVCALAGHLNEVTAVRFMQTKDQLLSFSKDKVLCLWDVSSQLCVQRVAGVFPKVQEDTHTLLFLREERQHLLLSFN 455          
BLAST of WD repeat-containing protein 49 vs. Ensembl Medaka
Match: ENSORLT00000004931.2 (pep primary_assembly:ASM223467v1:13:8822834:8840121:-1 gene:ENSORLG00000003946.2 transcript:ENSORLT00000004931.2 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 121.324 bits (303), Expect = 1.231e-28
Identity = 88/305 (28.85%), Postives = 143/305 (46.89%), Query Frame = 3
Query: 1137 CFTVHQGINSFAYNENLNLIATAGVNFQVCLWNPYVISKPNGLLRGHMASVTDVQFNKARGHLISFSKDKILRIWDVQLQVCIQRYAGVFPKGQEMY---SKMFYHEEKLRLFITFNFGLTMLEMKP----DVKDKISSHEKPLIGCLYNSLYNQVVTACQGGIIYCWMVDTGQRVKTITEICGPQAELTCITQDSTQTRLYTGATDGNVKIWDFN-GHCYNTLIVANGNPVDISQIVILKRCVLVFGFSKSITAFWTSSFKDHKVSPSPWKGVQTHKDDILSGASIPPHAVATGSYDGEIIIWN 2027
            C  +   + + +   N  ++ T G++  + LW+P+   KP G+L+GH A +  +  +     ++S S D       V+ + C+  + G   K   +Y   S   Y      L+I  +  + +L++KP      +    SH +P++ C Y+  + QVV+  +G ++  W +DTG R   ++E     A +TC+T D    RL TG  DG++KIW+FN G C  TL   + N     Q                 T    + +K +K +      +  HKDDIL  A  PP  +AT S DGEII+WN
Sbjct:    5 CLPLWSPVGTVSRVMNPKMLVTGGMDRLIRLWHPHFPGKPTGILKGHSAPIFFLWISSEDSQIVSVSVDCT-----VKDECCL--FTGE-SKASSIYGEISACHYSPAMKSLYIAAD-SIAVLKLKPRSFFPRRRLTESHNEPVLCCCYSEEFRQVVSCGEGSVLKVWDLDTG-RQGPVSERSSHGATITCMTMDDKGRRLITGRRDGSLKIWNFNSGQCLKTLKKGHANHCTTMQ-----------------TMNSNNLYKRYKATTFVSFQINGHKDDILCVAHCPPSLLATSSCDGEIIVWN 282          
BLAST of WD repeat-containing protein 49 vs. Ensembl Medaka
Match: ENSORLT00000040952.1 (pep primary_assembly:ASM223467v1:19:4064837:4070371:-1 gene:ENSORLG00000022716.1 transcript:ENSORLT00000040952.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 97.4413 bits (241), Expect = 1.048e-20
Identity = 99/406 (24.38%), Postives = 183/406 (45.07%), Query Frame = 3
Query:  192 GSHNRSQHFNGEEFVEALSLVLCKGTREEY-SDLFDKIDITREGYVDWEKFASHMLLEFYEKDDRTKSSS--LPQWKELKTLSGPHKDVIQRIVLVRNLN--RYLTISKEGNVGLWGSDCKLQK---VAKTHTESCRSRDLWVTDFAFLGNVNKVAVSFTSKEISFYDMNVKLEFNCQVKLENLFR---IPICMDY-WHHPDNNGEAIMAWGDTGGYINVILWSNISSSLFERVSSKA--------SDKDENTXXXXXXXXXXXXXKTCTYFSHKAHQDWVRKVSYIPNLECFVSCATNWNTSMVICWMEKYNPSNSTSSEMAGIPESRGFSRTSCFTVHQGINSFAYNENLNLIATAGVNFQVCLWNPYVISKPNGLLRGHMASVTDVQFNKARGHLISFSKDKI 1349
            G  ++      EEF ++LS V C  + E +  +LF +IDI+  G V W++  S++L E+ E+   +   +  L    +    S   ++   RI+ +      RY+T+SK G++ +W S  ++ +   V+     S R R  WVTD A++  +++VA+    ++  F  ++    F   V L   FR     +C  +    P+     ++  GD  G ++++ + N S  LF+R S           SD D++  ++           +C + ++  H+  + +V + P     ++ + +  TS+V   +            M   P    FS        QG   F Y+ +L L+ T G + ++ LW+ YV   P  +L+GH ASV DV   +    + S+S+D +
Sbjct:   65 GGPDKQPGIKLEEFKKSLSSVTC--SEESWIEELFCEIDISHAGEVTWQQLCSYLLQEYKERQRASTPPAALLDAQPQFTLCSQNKREPTVRILSISQQPPLRYITVSKGGHITVWSSSLRILQTFMVSGDPEHSSRLRG-WVTDAAYMRGLHRVAIVTDHRDAHFVKVSPTDIFE-DVHLFG-FRCVLTAVCFGFDSQRPEQ--PPLLLLGDEKGGVHLMWFLNTSKGLFKRASKTERGPQRILFSDLDDHDNMV-----------SCRHIAN-IHRAAINRVMFDPGANVIMTSSESETTSVVFMKVS-----------MKQEPYIWKFS--------QGALCFDYSSSLQLLVTGGKDRKIRLWSRYVTFSPLAVLQGHQASVMDVAIYQPVEQIFSYSRDSV 432          
BLAST of WD repeat-containing protein 49 vs. Planmine SMEST
Match: SMESG000041940.1 (SMESG000041940.1)

HSP 1 Score: 2223.36 bits (5760), Expect = 0.000e+0
Identity = 1123/1146 (97.99%), Postives = 1124/1146 (98.08%), Query Frame = 3
Query:   81 MNLNRSKESHTPLTENKLELKLNIKDLETLQEAFFMDGSHNRSQHFNGEEFVEALSLVLCKGTREEYSDLFDKIDITREGYVDWEKFASHMLLEFYEKDDRTKSSSLPQWKELKTLSGPHKDVIQRIVLVRNLNRYLTISKEGNVGLWGSDCKLQKVAKTHTESCRSRDLWVTDFAFLGNVNKVAVSFTSKEISFYDMNVKLEFNCQVKLENLFRIPICMDYWHHPDNNGEAIMAWGDTGGYINVILWSNISSSLFERVSSKASDKDENTXXXXXXXXXXXXXKTCTYFSHKAHQDWVRKVSYIPNLECFVSCATNWNTSMVICWMEKYNPSNSTSSEMAG--------IPESRGFSRTSCFTVHQGINSFAYNENLNLIATAGVNFQVCLWNPYVISKPNGLLRGHMASVTDVQFNKARGHLISFSKDKILRIWDVQLQVCIQRYAGVFPKGQE---------MYSKMFYHEEKLRLFITFNFGLTMLEMKPDVKDKISSHEKPLIGCLYNSLYNQVVTACQGGIIYCWMVDTGQRVKTITEICGPQAELTCITQDSTQTRLYTGATDGNVKIWDFNGHCYNTLIVANGNPVDISQIVILKRCVLVFGFSKSITAFWTSSFKDHKVSPSPWKGVQTHKDDILSGASIPPHAVATGSYDGEIIIWNINSEQASRTMTQRSQDEMKEVKKLAEQTIVRIKMAANAELKRAASNSIQQETDDKLDFIKAEIQNSIANRQXXXXXXXXXXXXXXXXXXXXDTVSDMQVQYKKMDVMFNISRLIYLESRKKIKHGGGANLISCGGNGIVRFWNSAEGWLIGEFVAHENASNIIMNTDVSNQYLVTGDMDGYIRVWDILSYCQTESENQKIMSPPTLISQWQSHSDEISGISFCFKFSRTLIITSSADQSAALWELNGVLIGRFGQEHRWKLGSXXXXXXXXXXXXHEDEVVKQEEDKYKVDPNWYPDPEAIQNPSGYRINTWKDTNLGKDYQELRVRKRERIQPSSIPDLPYLYGEKIGRPTFGPFYSLNISSFEEIEDIEQPEFMEYPEKFFNETEEFLTKTARVPLLNETLKAVFDERSLLPEYILEFEHKFRNRFQRHLSEAKVKLSLDDSNSFQEQLPRKAKTVRLKPIQEGSKYQKKLMHKLHIK 3467
            MNLNRSKESHTPLTENKLELKLNIKDLETLQEAFFMDGSHNRSQHFNGEEFVEALSLVLCKGTREEYSDLFDKIDITREGYVDWEKFASHMLLEFYEKDDRTKSSSLPQWKELKTLSGPHKDVIQRIVLVRNLNRYLTISKEGNVGLWGSDCKLQKVAKTHTESCRSRDLWVTDFAFLGNVNKVAVSFTSKEISFYDMNVKLEFNCQVKLENLFRIPICMDYWHHPDNNGEAIMAWGDTGGYINVILWSNISSSLFERVSSKASDKDENTIIISINDIIHGSIKTCTYFSHKAHQDWVRKVSYIPNLECFVSCATNWNTSMVICWMEKYNPSNSTSSEMAG        IPESRGFSRTSCFTVHQGINSFAYNENLNLIATAGVNFQVCLWNPYVISKPNGLLRGHMASVTDVQFNKARGHLISFSKDKILRIWDVQLQVCIQRYAGVFPKGQE         +YSKMFYHEEKLRLFITFNFGLTMLEMKPDVKDKISSHEKPLIGCLYNSLYNQVVTACQGGIIYCWMVDTGQRVKTITEICGPQAELTCITQDSTQTRLYTGATDGNVKIWDFNGHCYNTLIVANGNPVDISQIVILKRCVLVFGFSKSITAFWTSSFKDHKVSPSPWKGVQTHKDDILSGASIPPHAVATGSYDGEIIIWNINSEQASRTMTQRSQDEMKEVKKLAEQT     MAANAELKRAASNSIQQETDDKLDFIKAEIQNSIANRQIEESITTSTSSEETSTSSSTDTVSDMQVQYKKMDVMFNISRLIYLESRKKIKHGGGANLISCGGNGIVRFWNSAEGWLIGEFVAHENASNIIMNTDVSNQYLVTGDMDGYIRVWDILSYCQTESENQKIMSPPTLISQWQSHSDEISGISFCFKFSRTLIITSSADQSAALWELNGVLIGRFGQEHRWKLGSIIETPTIAAIETHEDEVVKQEEDKYKVDPNWYPDPEAIQNPSGYRINTWKDTNLGKDYQELRVRKRERIQPSSIPDLPYLYGEKIGRPTFGPFYSLNISSFEEIEDIEQPEFMEYPEKFFNETEEFLTKTARVPLLNETLKAVFDERSLLPEYILEFEHKFRNRFQRHLSEAKVKLSLDDSNSFQEQLPRKAKTVRLKPIQEGSKYQKKLMHKLHIK
Sbjct:    1 MNLNRSKESHTPLTENKLELKLNIKDLETLQEAFFMDGSHNRSQHFNGEEFVEALSLVLCKGTREEYSDLFDKIDITREGYVDWEKFASHMLLEFYEKDDRTKSSSLPQWKELKTLSGPHKDVIQRIVLVRNLNRYLTISKEGNVGLWGSDCKLQKVAKTHTESCRSRDLWVTDFAFLGNVNKVAVSFTSKEISFYDMNVKLEFNCQVKLENLFRIPICMDYWHHPDNNGEAIMAWGDTGGYINVILWSNISSSLFERVSSKASDKDENTIIISINDIIHGSIKTCTYFSHKAHQDWVRKVSYIPNLECFVSCATNWNTSMVICWMEKYNPSNSTSSEMAGSKDEFISDIPESRGFSRTSCFTVHQGINSFAYNENLNLIATAGVNFQVCLWNPYVISKPNGLLRGHMASVTDVQFNKARGHLISFSKDKILRIWDVQLQVCIQRYAGVFPKGQESALMNPRIILYSKMFYHEEKLRLFITFNFGLTMLEMKPDVKDKISSHEKPLIGCLYNSLYNQVVTACQGGIIYCWMVDTGQRVKTITEICGPQAELTCITQDSTQTRLYTGATDGNVKIWDFNGHCYNTLIVANGNPVDISQIVILKRCVLVFGFSKSITAFWTSSFKDHKVSPSPWKGVQTHKDDILSGASIPPHAVATGSYDGEIIIWNINSEQASRTMTQRSQDEMKEVKKLAEQT-----MAANAELKRAASNSIQQETDDKLDFIKAEIQNSIANRQIEESITTSTSSEETSTSSSTDTVSDMQVQYKKMDVMFNISRLIYLESRKKIKHGGGANLISCGGNGIVRFWNSAEGWLIGEFVAHENASNIIMNTDVSNQYLVTGDMDGYIRVWDILSYCQTESENQKIMSPPTLISQWQSHSDEISGISFCFKFSRTLIITSSADQSAALWELNGVLIGRFGQEHRWKLGSIIETPTIAAIETHEDEVVKQEEDKYKVDPNWYPDPEAIQNPSGYRINTWKDTNLGKDYQELRVRKRERIQPSSIPDLPYLYGEKIGRPTFGPFYSLNISSFEEIEDIEQPEFMEYPEKFFNETEEFLTKTARVPLLNETLKAVFDERSLLPEYILEFEHKFRNRFQRHLSEAKVKLSLDDSNSFQEQLPRKAKTVRLKPIQEGSKYQKKLMHKLHIK 1141          
BLAST of WD repeat-containing protein 49 vs. Planmine SMEST
Match: SMESG000041940.1 (SMESG000041940.1)

HSP 1 Score: 2217.19 bits (5744), Expect = 0.000e+0
Identity = 1124/1161 (96.81%), Postives = 1124/1161 (96.81%), Query Frame = 3
Query:   81 MNLNRSKESHTPLTENKLELKLNIKDLETLQEAFFMDGSHNRSQHFNGEEFVEALSLVLCKGTREEYSDLFDKIDITREGYVDWEKFASHMLLEFYEKDDRTKSSSLPQWKELKTLSGPHKDVIQRIVLVRNLNRYLTISKEGNVGLWGSDCKLQKVAKTHTESCRSRDLWVTDFAFLGNVNKVAVSFTSKEISFYDMNVKLEFNCQVKLENLFRIPICMDYWHHPDNNGEAIMAWGDTGGYINVILWSNISSSLFERVSSKASDKDENTXXXXXXXXXXXXXKTCTYFSHKAHQDWVRKVSYIPNLECFVSCATNWNTSMVICWMEKYNPSNSTSSEMAG--------IPESRGFSRTSCFTVHQGINSFAYNENLNLIATAGVNFQVCLWNPYVISKPNGLLRGHMASVTDVQFNKARGHLISFSKDKILRIWDVQLQVCIQRYAGVFPKGQEMYSKMFYHEEKLRLFITFNFGLTMLEMKPDVKDKISSHEKPLIGCLYNSLYNQVVTACQGGIIYCWMVDTGQRVKTITEICGPQAELTCITQDSTQTRLYTGATDGNVKIWDFNGHCYNTLIVANGNPVDISQIVILKRCVLVFGFSKSITAFWTSSFKDHKVSPSPWKGVQTHKDDILSGASIPPHAVATGSYDGEIIIWNINSEQASRTMTQRSQDEMKEVKKLAEQTIVRIKMAANAELKRAASNSIQQETDDKLDFIKAEIQNSIANRQXXXXXXXXXXXXXXXXXXXXDTVSDMQVQYKKMDVMFNISRLIYLESRKKIKHGGGANLISCGGNGIVRFWNSAEGWLIGEFVAHENASNIIMNTDVSNQYLVTGDMDGYIRVWDILSYCQTESENQKIMSPPTLISQWQSHSDEISGISFCFKFSRTLIITSSADQSAALWELNGVLIGRFGQEHRWKLGSXXXXXXXXXXXXHEDEVVKQEEDKYKVDPNWYPDPEAIQNPSGYRINTWKDTNLGKDYQELRVRKRERIQPSSIPDLPYLYGEKIGRPTFGPFYSLNISSFEEIEDIEQPEFMEYPEKFFNETEEFLTKTARVPLLN------------------------ETLKAVFDERSLLPEYILEFEHKFRNRFQRHLSEAKVKLSLDDSNSFQEQLPRKAKTVRLKPIQEGSKYQKKLMHKLHIK 3467
            MNLNRSKESHTPLTENKLELKLNIKDLETLQEAFFMDGSHNRSQHFNGEEFVEALSLVLCKGTREEYSDLFDKIDITREGYVDWEKFASHMLLEFYEKDDRTKSSSLPQWKELKTLSGPHKDVIQRIVLVRNLNRYLTISKEGNVGLWGSDCKLQKVAKTHTESCRSRDLWVTDFAFLGNVNKVAVSFTSKEISFYDMNVKLEFNCQVKLENLFRIPICMDYWHHPDNNGEAIMAWGDTGGYINVILWSNISSSLFERVSSKASDKDENTIIISINDIIHGSIKTCTYFSHKAHQDWVRKVSYIPNLECFVSCATNWNTSMVICWMEKYNPSNSTSSEMAG        IPESRGFSRTSCFTVHQGINSFAYNENLNLIATAGVNFQVCLWNPYVISKPNGLLRGHMASVTDVQFNKARGHLISFSKDKILRIWDVQLQVCIQRYAGVFPKGQEMYSKMFYHEEKLRLFITFNFGLTMLEMKPDVKDKISSHEKPLIGCLYNSLYNQVVTACQGGIIYCWMVDTGQRVKTITEICGPQAELTCITQDSTQTRLYTGATDGNVKIWDFNGHCYNTLIVANGNPVDISQIVILKRCVLVFGFSKSITAFWTSSFKDHKVSPSPWKGVQTHKDDILSGASIPPHAVATGSYDGEIIIWNINSEQASRTMTQRSQDEMKEVKKLAEQT     MAANAELKRAASNSIQQETDDKLDFIKAEIQNSIANRQIEESITTSTSSEETSTSSSTDTVSDMQVQYKKMDVMFNISRLIYLESRKKIKHGGGANLISCGGNGIVRFWNSAEGWLIGEFVAHENASNIIMNTDVSNQYLVTGDMDGYIRVWDILSYCQTESENQKIMSPPTLISQWQSHSDEISGISFCFKFSRTLIITSSADQSAALWELNGVLIGRFGQEHRWKLGSIIETPTIAAIETHEDEVVKQEEDKYKVDPNWYPDPEAIQNPSGYRINTWKDTNLGKDYQELRVRKRERIQPSSIPDLPYLYGEKIGRPTFGPFYSLNISSFEEIEDIEQPEFMEYPEKFFNETEEFLTKTARVPLLN                        ETLKAVFDERSLLPEYILEFEHKFRNRFQRHLSEAKVKLSLDDSNSFQEQLPRKAKTVRLKPIQEGSKYQKKLMHKLHIK
Sbjct:    1 MNLNRSKESHTPLTENKLELKLNIKDLETLQEAFFMDGSHNRSQHFNGEEFVEALSLVLCKGTREEYSDLFDKIDITREGYVDWEKFASHMLLEFYEKDDRTKSSSLPQWKELKTLSGPHKDVIQRIVLVRNLNRYLTISKEGNVGLWGSDCKLQKVAKTHTESCRSRDLWVTDFAFLGNVNKVAVSFTSKEISFYDMNVKLEFNCQVKLENLFRIPICMDYWHHPDNNGEAIMAWGDTGGYINVILWSNISSSLFERVSSKASDKDENTIIISINDIIHGSIKTCTYFSHKAHQDWVRKVSYIPNLECFVSCATNWNTSMVICWMEKYNPSNSTSSEMAGSKDEFISDIPESRGFSRTSCFTVHQGINSFAYNENLNLIATAGVNFQVCLWNPYVISKPNGLLRGHMASVTDVQFNKARGHLISFSKDKILRIWDVQLQVCIQRYAGVFPKGQEMYSKMFYHEEKLRLFITFNFGLTMLEMKPDVKDKISSHEKPLIGCLYNSLYNQVVTACQGGIIYCWMVDTGQRVKTITEICGPQAELTCITQDSTQTRLYTGATDGNVKIWDFNGHCYNTLIVANGNPVDISQIVILKRCVLVFGFSKSITAFWTSSFKDHKVSPSPWKGVQTHKDDILSGASIPPHAVATGSYDGEIIIWNINSEQASRTMTQRSQDEMKEVKKLAEQT-----MAANAELKRAASNSIQQETDDKLDFIKAEIQNSIANRQIEESITTSTSSEETSTSSSTDTVSDMQVQYKKMDVMFNISRLIYLESRKKIKHGGGANLISCGGNGIVRFWNSAEGWLIGEFVAHENASNIIMNTDVSNQYLVTGDMDGYIRVWDILSYCQTESENQKIMSPPTLISQWQSHSDEISGISFCFKFSRTLIITSSADQSAALWELNGVLIGRFGQEHRWKLGSIIETPTIAAIETHEDEVVKQEEDKYKVDPNWYPDPEAIQNPSGYRINTWKDTNLGKDYQELRVRKRERIQPSSIPDLPYLYGEKIGRPTFGPFYSLNISSFEEIEDIEQPEFMEYPEKFFNETEEFLTKTARVPLLNENNPKNVTHNLNTSNVNSNSGNSVETLKAVFDERSLLPEYILEFEHKFRNRFQRHLSEAKVKLSLDDSNSFQEQLPRKAKTVRLKPIQEGSKYQKKLMHKLHIK 1156          
BLAST of WD repeat-containing protein 49 vs. Planmine SMEST
Match: SMESG000041940.1 (SMESG000041940.1)

HSP 1 Score: 2191.77 bits (5678), Expect = 0.000e+0
Identity = 1117/1170 (95.47%), Postives = 1118/1170 (95.56%), Query Frame = 3
Query:   81 MNLNRSKESHTPLTENKLELKLNIKDLETLQEAFFMDGSHNRSQHFNGEEFVEALSLVLCKGTREEYSDLFDKIDITREGYVDWEKFASHMLLEFYEKDDRTKSSSLPQWKELKTLSGPHKDVIQRIVLVRNLNRYLTISKEGNVGLWGSDCKLQKVAKTHTESCRSRDLWVTDFAFLGNVNKVAVSFTSKEISFYDMNVKLEFNCQVKLENLFRIPICMDYWHHPDNNGEAIMAWGDTGGYINVILWSNISSSLFERVSSKASDKDENTXXXXXXXXXXXXXKTCTYFSHKAHQDWVRKVSYIPNLECFVSCATNWNTSMVICWMEKYNPSNSTSSEMAG--------IPESRGFSRTSCFTVHQGINSFAYNENLNLIATAGVNFQVCLWNPYVISKPNGLLRGHMASVTDVQFNKARGHLISFSKDKILRIWDVQLQVCIQRYAGVFPKGQE---------MYSKMFYHEEKLRLFITFNFGLTMLEMKPDVKDKISSHEKPLIGCLYNSLYNQVVTACQGGIIYCWMVDTGQRVKTITEICGPQAELTCITQDSTQTRLYTGATDGNVKIWDFNGHCYNTLIVANGNPVDISQIVILKRCVLVFGFSKSITAFWTSSFKDHKVSPSPWKGVQTHKDDILSGASIPPHAVATGSYDGEIIIWNINSEQASRTMTQRSQDEMKEVKKLAEQTIVRIKMAANAELKRAASNSIQQETDDKLDFIKAEIQNSIANRQXXXXXXXXXXXXXXXXXXXXDTVSDMQVQYKKMDVMFNISRLIYLESRKKIKHGGGANLISCGGNGIVRFWNSAEGWLIGEFVAHENASNIIMNTDVSNQYLVTGDMDGYIRVWDILSYCQTESENQKIMSPPTLISQWQSHSDEISGISFCFKFSRTLIITSSADQSAALWELNGVLIGRFGQEHRWKLGSXXXXXXXXXXXXHEDEVVKQEEDKYKVDPNWYPDPEAIQNPSGYRINTWKDTNLGKDYQELRVRKRERIQPSSIPDLPYLYGEKIGRPTFGPFYSLNISSFEEIEDIEQPEFMEYPEKFFNETEEFLTKTARVPLLN------------------------ETLKAVFDERSLLPEYILEFEHKFRNRFQRHLSEAKVKLSLDDSNSFQEQLPRKAKTVRLKPIQEGSKYQKKLMHKLHIK 3467
            MNLNRSKESHTPLTENKLELKLNIKDLETLQEAFFMDGSHNRSQHFNGEEFVEALSLVLCKGTREEYSDLFDKIDITREGYVDWEKFASHMLLEFYEKDDRTKSSSLPQWKELKTLSGPHKDVIQRIVLVRNLNRYLTISKEGNVGLWGSDCKLQKVAKTHTESCRSRDLWVTDFAFLGNVNKVAVSFTSKEISFYDMNVKLEFNCQVKLENLFRIPICMDYWHHPDNNGEAIMAWGDTGGYINVILWSNISSSLFERVSSKASDKDENTIIISINDIIHGSIKTCTYFSHKAHQDWVRKVSYIPNLECFVSCATNWNTSMVICWMEKYNPSNSTSSEMAG        IPESRGFSRTSCFTVHQGINSFAYNENLNLIATAGVNFQVCLWNPYVISKPNGLLRGHMASVTDVQFNKARGHLISFSKDKILRIWDVQLQVCIQRYAGVFPKGQE         +YSKMFYHEEKLRLFITFNFGLTMLEMKPDVKDKISSHEKPLIGCLYNSLYNQVVTACQGGIIYCWMVDTGQRVKTITEICGPQAELTCITQDSTQTRLYTGATDGNVKIWDFNGHCYNTLIVANGNPVDISQIVILKRCVLVFGFSKSITAFWTSSFKDHKVSPSPWKGVQTHKDDILSGASIPPHAVATGSYDGEIIIWNINSEQASRTMTQRSQDEMKEVKKLAEQT     MAANAELKRAASNSIQQETDDKLDFIKAEIQNSIANRQIEESITTSTSSEETSTSSSTDTVSDM      MDVMFNISRLIYLESRKKIKHGGGANLISCGGNGIVRFWNSAEGWLIGEFVAHENASNIIMNTDVSNQYLVTGDMDGYIRVWDILSYCQTESENQKIMSPPTLISQWQSHSDEISGISFCFKFSRTLIITSSADQSAALWELNGVLIGRFGQEHRWKLGSIIETPTIAAIETHEDEVVKQEEDKYKVDPNWYPDPEAIQNPSGYRINTWKDTNLGKDYQELRVRKRERIQPSSIPDLPYLYGEKIGRPTFGPFYSLNISSFEEIEDIEQPEFMEYPEKFFNETEEFLTKTARVPLLN                        ETLKAVFDERSLLPEYILEFEHKFRNRFQRHLSEAKVKLSLDDSNSFQEQLPRKAKTVRLKPIQEGSKYQKKLMHKLHIK
Sbjct:    1 MNLNRSKESHTPLTENKLELKLNIKDLETLQEAFFMDGSHNRSQHFNGEEFVEALSLVLCKGTREEYSDLFDKIDITREGYVDWEKFASHMLLEFYEKDDRTKSSSLPQWKELKTLSGPHKDVIQRIVLVRNLNRYLTISKEGNVGLWGSDCKLQKVAKTHTESCRSRDLWVTDFAFLGNVNKVAVSFTSKEISFYDMNVKLEFNCQVKLENLFRIPICMDYWHHPDNNGEAIMAWGDTGGYINVILWSNISSSLFERVSSKASDKDENTIIISINDIIHGSIKTCTYFSHKAHQDWVRKVSYIPNLECFVSCATNWNTSMVICWMEKYNPSNSTSSEMAGSKDEFISDIPESRGFSRTSCFTVHQGINSFAYNENLNLIATAGVNFQVCLWNPYVISKPNGLLRGHMASVTDVQFNKARGHLISFSKDKILRIWDVQLQVCIQRYAGVFPKGQESALMNPRIILYSKMFYHEEKLRLFITFNFGLTMLEMKPDVKDKISSHEKPLIGCLYNSLYNQVVTACQGGIIYCWMVDTGQRVKTITEICGPQAELTCITQDSTQTRLYTGATDGNVKIWDFNGHCYNTLIVANGNPVDISQIVILKRCVLVFGFSKSITAFWTSSFKDHKVSPSPWKGVQTHKDDILSGASIPPHAVATGSYDGEIIIWNINSEQASRTMTQRSQDEMKEVKKLAEQT-----MAANAELKRAASNSIQQETDDKLDFIKAEIQNSIANRQIEESITTSTSSEETSTSSSTDTVSDM------MDVMFNISRLIYLESRKKIKHGGGANLISCGGNGIVRFWNSAEGWLIGEFVAHENASNIIMNTDVSNQYLVTGDMDGYIRVWDILSYCQTESENQKIMSPPTLISQWQSHSDEISGISFCFKFSRTLIITSSADQSAALWELNGVLIGRFGQEHRWKLGSIIETPTIAAIETHEDEVVKQEEDKYKVDPNWYPDPEAIQNPSGYRINTWKDTNLGKDYQELRVRKRERIQPSSIPDLPYLYGEKIGRPTFGPFYSLNISSFEEIEDIEQPEFMEYPEKFFNETEEFLTKTARVPLLNENNPKNVTHNLNTSNVNSNSGNSVETLKAVFDERSLLPEYILEFEHKFRNRFQRHLSEAKVKLSLDDSNSFQEQLPRKAKTVRLKPIQEGSKYQKKLMHKLHIK 1159          
BLAST of WD repeat-containing protein 49 vs. Planmine SMEST
Match: SMESG000041940.1 (SMESG000041940.1)

HSP 1 Score: 1447.18 bits (3745), Expect = 0.000e+0
Identity = 740/763 (96.99%), Postives = 741/763 (97.12%), Query Frame = 3
Query:   81 MNLNRSKESHTPLTENKLELKLNIKDLETLQEAFFMDGSHNRSQHFNGEEFVEALSLVLCKGTREEYSDLFDKIDITREGYVDWEKFASHMLLEFYEKDDRTKSSSLPQWKELKTLSGPHKDVIQRIVLVRNLNRYLTISKEGNVGLWGSDCKLQKVAKTHTESCRSRDLWVTDFAFLGNVNKVAVSFTSKEISFYDMNVKLEFNCQVKLENLFRIPICMDYWHHPDNNGEAIMAWGDTGGYINVILWSNISSSLFERVSSKASDKDENTXXXXXXXXXXXXXKTCTYFSHKAHQDWVRKVSYIPNLECFVSCATNWNTSMVICWMEKYNPSNSTSSEMAG--------IPESRGFSRTSCFTVHQGINSFAYNENLNLIATAGVNFQVCLWNPYVISKPNGLLRGHMASVTDVQFNKARGHLISFSKDKILRIWDVQLQVCIQRYAGVFPKGQE---------MYSKMFYHEEKLRLFITFNFGLTMLEMKPDVKDKISSHEKPLIGCLYNSLYNQVVTACQGGIIYCWMVDTGQRVKTITEICGPQAELTCITQDSTQTRLYTGATDGNVKIWDFNGHCYNTLIVANGNPVDISQIVILKRCVLVFGFSKSITAFWTSSFKDHKVSPSPWKGVQTHKDDILSGASIPPHAVATGSYDGEIIIWNINSEQASRTMTQRSQDEMKEVKKLAEQTIVRIKMAANAELKRAASNSIQQETDDKLDFIKAEIQNSIANRQXXXXXXXXXXXXXXXXXXXXDTVSDM 2318
            MNLNRSKESHTPLTENKLELKLNIKDLETLQEAFFMDGSHNRSQHFNGEEFVEALSLVLCKGTREEYSDLFDKIDITREGYVDWEKFASHMLLEFYEKDDRTKSSSLPQWKELKTLSGPHKDVIQRIVLVRNLNRYLTISKEGNVGLWGSDCKLQKVAKTHTESCRSRDLWVTDFAFLGNVNKVAVSFTSKEISFYDMNVKLEFNCQVKLENLFRIPICMDYWHHPDNNGEAIMAWGDTGGYINVILWSNISSSLFERVSSKASDKDENTIIISINDIIHGSIKTCTYFSHKAHQDWVRKVSYIPNLECFVSCATNWNTSMVICWMEKYNPSNSTSSEMAG        IPESRGFSRTSCFTVHQGINSFAYNENLNLIATAGVNFQVCLWNPYVISKPNGLLRGHMASVTDVQFNKARGHLISFSKDKILRIWDVQLQVCIQRYAGVFPKGQE         +YSKMFYHEEKLRLFITFNFGLTMLEMKPDVKDKISSHEKPLIGCLYNSLYNQVVTACQGGIIYCWMVDTGQRVKTITEICGPQAELTCITQDSTQTRLYTGATDGNVKIWDFNGHCYNTLIVANGNPVDISQIVILKRCVLVFGFSKSITAFWTSSFKDHKVSPSPWKGVQTHKDDILSGASIPPHAVATGSYDGEIIIWNINSEQASRTMTQRSQDEMKEVKKLAEQT     MAANAELKRAASNSIQQETDDKLDFIKAEIQNSIANRQIEESITTSTSSEETSTSSSTDTVSDM
Sbjct:    1 MNLNRSKESHTPLTENKLELKLNIKDLETLQEAFFMDGSHNRSQHFNGEEFVEALSLVLCKGTREEYSDLFDKIDITREGYVDWEKFASHMLLEFYEKDDRTKSSSLPQWKELKTLSGPHKDVIQRIVLVRNLNRYLTISKEGNVGLWGSDCKLQKVAKTHTESCRSRDLWVTDFAFLGNVNKVAVSFTSKEISFYDMNVKLEFNCQVKLENLFRIPICMDYWHHPDNNGEAIMAWGDTGGYINVILWSNISSSLFERVSSKASDKDENTIIISINDIIHGSIKTCTYFSHKAHQDWVRKVSYIPNLECFVSCATNWNTSMVICWMEKYNPSNSTSSEMAGSKDEFISDIPESRGFSRTSCFTVHQGINSFAYNENLNLIATAGVNFQVCLWNPYVISKPNGLLRGHMASVTDVQFNKARGHLISFSKDKILRIWDVQLQVCIQRYAGVFPKGQESALMNPRIILYSKMFYHEEKLRLFITFNFGLTMLEMKPDVKDKISSHEKPLIGCLYNSLYNQVVTACQGGIIYCWMVDTGQRVKTITEICGPQAELTCITQDSTQTRLYTGATDGNVKIWDFNGHCYNTLIVANGNPVDISQIVILKRCVLVFGFSKSITAFWTSSFKDHKVSPSPWKGVQTHKDDILSGASIPPHAVATGSYDGEIIIWNINSEQASRTMTQRSQDEMKEVKKLAEQT-----MAANAELKRAASNSIQQETDDKLDFIKAEIQNSIANRQIEESITTSTSSEETSTSSSTDTVSDM 758          
BLAST of WD repeat-containing protein 49 vs. Planmine SMEST
Match: SMESG000033045.1 (SMESG000033045.1)

HSP 1 Score: 262.307 bits (669), Expect = 1.067e-71
Identity = 187/677 (27.62%), Postives = 332/677 (49.04%), Query Frame = 3
Query:  126 NKLELKLNIKDLETLQEAFFMDGSHNRSQHFNGEEFVEALSLVLCKGTREEYSD--LFDKIDITREGYVDWEKFASHMLLEFYEKDD-----RTKSSSLPQWKELKTLSGPHKDVIQRIVLVRNLNRYLTISKEGNVGLWGSDCKLQKVAKTHT--ESCRSRDLWVTDFAFLGNVNKVAVSFTSKEISFYDMNVKLEFNCQVKLENLFRIPICMDYWHHPDNNGEAIMAWGDTGGYINVILWSNISSSLFERVSSKASDKDENTXXXXXXXXXXXXXKTCTYFSHKAHQDWVRKVSYIPNLECFVSCATNWNTSMVICWME---------KYNPSNSTSSEMAGI-----PESRGFSRTSCFTVHQGINSFAYNENLNLIATAGVNFQVCLWNPYVISKPNGLLRGHMASVTDVQFNKARGHLISFSKDKILRIWDVQLQVCIQRYAGVFPKGQ----EMYSKMFYHEEKLRLFITFNFGLTMLEMKPDVKDKIS-SHEKPLIGCLYNSLYNQVVTACQGGIIYCWMVDTGQRVKTITEICGPQAELTCITQDSTQTRLYTGATDGNVKIWDF-NGHCYNTLIVANGNP--VDISQI----VILKRCVLVFGFSKSITAFWTSSFKDHKVSPSP---WKGVQT--HKDDILSGASIPPHAVATGSYDGEIIIWNINS 2036
            +K+E ++++  LE L+ AF  +  ++RS   +  EF   L   L   T E+     LF KID    G ++W++F ++M LE+ EK++     R  +  LP   E    + PH++ + RI    +   ++  S +G +  W +  +L+K     T  +S R +  W+ DF  +   NK+ V+   +EI F++++    F    ++ +L  +P+C+DY+   DN  + ++ WGD  G +N++        L    + K   + E    I + +++     +  ++  K H DWV K+ Y  +L   +SC+ +  T++VI  +E         K    + T S+         P+ R  +  + F +++GI +F + ++ N++ T G++  + LWNPYV SKP G+LRGH   +  V   +    + S   DK +++WD+    C+     V PKG     +M S  +    K  +  T    +  +++KP +   ++ +H+ P+  C YN  +NQVVT C+G  +  W + TG++V    E     + +TC+T DST  RL TG  DG V++W+F NGHC   L     +    +IS +    +   + ++  G+ ++I  +          S  P   W    +  HK+DIL+ A++  H +AT  Y G II+WN+ S
Sbjct:  119 DKIEERIDLTVLEELKAAF-ENAEYDRSGKLDLSEFKALLKEKLQLPTFEDIQTETLFKKIDWASSGAINWDEFCTYMQLEYAEKEETYLKAREMAFCLPARIE----NTPHRENVIRITSTSD-GSFIAGSTDGILSFWSNTLELKKCKSVVTIEQSQRVKSKWIIDFLIMNEFNKIIVATGDREIEFFELS---SFEPYCRIHSLENVPLCLDYYVDKDNLDDCLILWGDRKGCVNILHLHATGECL---RTWKKQPRSEGIAGIGMENVLSN--PSIKFYRWKVHNDWVLKLKYYDSLRQIISCSNDEATALVIGCVEGSTQLDQQMKLKSMHQTKSKDMTFGNMLQPKRRISTDQTVFNIYKGIQTFDFGKSKNVLVTGGLDRIIRLWNPYVNSKPTGMLRGHNKPLVYVHIAEQENRIFSICADKCVKVWDLHDHNCL---LTVRPKGHRIRGDMQSCHYSDFAKSLMIATDQVSMLNIKIKPVLHTDVAVTHKDPVTCCKYNEAFNQVVTCCEGSTVKLWNLSTGEKVFEFNE-AHEDSGVTCLTFDSTGRRLLTGGRDGMVRMWNFNNGHCLTELKKEESDLKYAEISAVEYVEISRNKFIVSVGWDRAINVYIDQCEPGMHKSYYPQSRWLDDMSNGHKEDILTLATLKGHLLATADYHGTIIVWNLMS 777          

HSP 2 Score: 87.0409 bits (214), Expect = 7.194e-17
Identity = 52/175 (29.71%), Postives = 88/175 (50.29%), Query Frame = 3
Query: 2307 VSDMQVQYKKMDVMFNISRLIYLESRKKIKHGGGANLISCGGNGIVRFWNSAEGWLI-GEFVAHENASNIIM------NTDVSNQYLVTGDMDGYIRVWDILSYCQTESENQKIMSPPTLISQWQSHSDEISGISFCFKFSRTLIITSSADQSAALWELNGVLIGRFGQEHRWKL 2810
            V+D+      +D   +I++L++L+SR K K    A+L++ G  G+V FWN  EG ++ G F     +   +       + D+ ++ L  GD  G+I VWDI +Y   + E       P L+ +W++H   I+ +    +    ++ITSS D +  +W   G  +G FGQ   W L
Sbjct:  788 VADLDEDTDYIDEDLSINKLLFLQSRAKNK--SSASLVASGPYGLVHFWNVKEGGILYGRFKGGTESGQSLTAMIACKDQDIDDKLLFIGDRFGFISVWDIENYANNKVET----DCPELLRRWRAHVSSITSLDLVLQ--SQVLITSSDDCTVRVWTFEGEYVGTFGQTEMWDL 954          
The following BLAST results are available for this feature:
BLAST of WD repeat-containing protein 49 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
WDR498.736e-17743.40WD repeat domain 49 [Source:HGNC Symbol;Acc:HGNC:2... [more]
WDR495.331e-12643.86WD repeat domain 49 [Source:HGNC Symbol;Acc:HGNC:2... [more]
WDR491.614e-12442.77WD repeat domain 49 [Source:HGNC Symbol;Acc:HGNC:2... [more]
WDR491.471e-9347.58WD repeat domain 49 [Source:HGNC Symbol;Acc:HGNC:2... [more]
EFCAB81.745e-7825.65EF-hand calcium binding domain 8 [Source:HGNC Symb... [more]
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BLAST of WD repeat-containing protein 49 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 3
Match NameE-valueIdentityDescription
snrp-40.29.180e-928.44Small Nuclear RibonucleoProtein homolog [Source:U... [more]
snrp-40.11.008e-628.92Small Nuclear RibonucleoProtein homolog [Source:U... [more]
F13H8.23.302e-627.42pep chromosome:WBcel235:II:6270370:6274005:1 gene:... [more]
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BLAST of WD repeat-containing protein 49 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 1
Match NameE-valueIdentityDescription
WDY2.367e-3923.39gene:FBgn0267449 transcript:FBtr0347028[more]
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BLAST of WD repeat-containing protein 49 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 4
Match NameE-valueIdentityDescription
wdr951.488e-6430.12WD40 repeat domain 95 [Source:ZFIN;Acc:ZDB-GENE-13... [more]
si:dkey-202c14.37.856e-4625.93si:dkey-202c14.3 [Source:ZFIN;Acc:ZDB-GENE-121214-... [more]
wdr53.186e-820.75WD repeat domain 5 [Source:ZFIN;Acc:ZDB-GENE-04042... [more]
taf52.752e-625.41TAF5 RNA polymerase II, TATA box binding protein (... [more]
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BLAST of WD repeat-containing protein 49 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
wdr490.000e+038.48WD repeat domain 49 [Source:NCBI gene;Acc:549615][more]
ENSXETT00000013976.18.604e-5925.57EF-hand calcium binding domain 8 [Source:NCBI gene... [more]
ENSXETT00000029824.11.079e-5825.57EF-hand calcium binding domain 8 [Source:NCBI gene... [more]
ENSXETT00000025824.15.218e-5226.84WD repeat-containing protein 64-like [Source:NCBI ... [more]
ENSXETT00000013991.13.634e-5026.31EF-hand calcium binding domain 8 [Source:NCBI gene... [more]
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BLAST of WD repeat-containing protein 49 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Wdr495.739e-14936.48WD repeat domain 49 [Source:MGI Symbol;Acc:MGI:364... [more]
Wdr495.692e-12542.17WD repeat domain 49 [Source:MGI Symbol;Acc:MGI:364... [more]
Wdr491.280e-12343.49WD repeat domain 49 [Source:MGI Symbol;Acc:MGI:364... [more]
Efcab83.255e-8125.05EF-hand calcium binding domain 8 [Source:MGI Symbo... [more]
Wdr951.036e-4428.71WD40 repeat domain 95 [Source:MGI Symbol;Acc:MGI:1... [more]
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BLAST of WD repeat-containing protein 49 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q8IV35|WDR49_HUMAN7.065e-9347.58WD repeat-containing protein 49 OS=Homo sapiens OX... [more]
sp|Q17I16|WDY_AEDAE1.504e-4422.68WD repeat-containing protein on Y chromosome OS=Ae... [more]
sp|B4F7L9|WDY_DROME2.373e-3823.39WD repeat-containing protein on Y chromosome OS=Dr... [more]
sp|Q9D565|WDR64_MOUSE2.532e-3829.10WD repeat-containing protein 64 OS=Mus musculus OX... [more]
sp|B7FF09|WDY_DROWI2.657e-3823.03WD repeat-containing protein on Y chromosome OS=Dr... [more]
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BLAST of WD repeat-containing protein 49 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A1S3JWS00.000e+045.87WD repeat-containing protein 49-like OS=Lingula un... [more]
A0A1S3JX590.000e+045.87WD repeat-containing protein 49 OS=Lingula unguis ... [more]
R7UEX80.000e+047.22WD_REPEATS_REGION domain-containing protein OS=Cap... [more]
A0A2T7PSF00.000e+048.51Uncharacterized protein OS=Pomacea canaliculata OX... [more]
A0A210PY340.000e+045.73WD repeat-containing protein 49 OS=Mizuhopecten ye... [more]
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BLAST of WD repeat-containing protein 49 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
wdr951.057e-7129.47WD repeat-containing protein on Y chromosome-like ... [more]
ENSAMXT00000043902.14.379e-5837.54pep primary_assembly:Astyanax_mexicanus-2.0:APWO02... [more]
si:dkey-202c14.32.831e-3924.18si:dkey-202c14.3 [Source:ZFIN;Acc:ZDB-GENE-121214-... [more]
si:dkey-202c14.31.952e-2828.90si:dkey-202c14.3 [Source:ZFIN;Acc:ZDB-GENE-121214-... [more]
wdr52.951e-820.75WD repeat domain 5 [Source:NCBI gene;Acc:103033424... [more]
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BLAST of WD repeat-containing protein 49 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 4
Match NameE-valueIdentityDescription
ENSPMAT00000005521.11.888e-3729.34pep scaffold:Pmarinus_7.0:GL477585:56150:70911:-1 ... [more]
WDR867.727e-1123.56WD repeat domain 86 [Source:HGNC Symbol;Acc:HGNC:2... [more]
snrnp406.465e-721.43small nuclear ribonucleoprotein 40 (U5) [Source:ZF... [more]
ENSPMAT00000008862.16.571e-725.21pep scaffold:Pmarinus_7.0:GL476579:86637:114999:1 ... [more]
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BLAST of WD repeat-containing protein 49 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of WD repeat-containing protein 49 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO443277.703e-6746.21Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO386271.955e-7329.76Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO364382.956e-4825.88Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO389844.500e-2830.50Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO309645.055e-2329.30Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of WD repeat-containing protein 49 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSORLT00000015414.22.715e-9336.92WD repeat-containing protein 64 [Source:NCBI gene;... [more]
ENSORLT00000043076.12.715e-9336.92WD repeat-containing protein 64 [Source:NCBI gene;... [more]
ENSORLT00000037247.12.715e-9336.92WD repeat-containing protein 64 [Source:NCBI gene;... [more]
ENSORLT00000004931.21.231e-2828.85pep primary_assembly:ASM223467v1:13:8822834:884012... [more]
ENSORLT00000040952.11.048e-2024.38pep primary_assembly:ASM223467v1:19:4064837:407037... [more]
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BLAST of WD repeat-containing protein 49 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000041940.10.000e+097.99SMESG000041940.1[more]
SMESG000041940.10.000e+096.81SMESG000041940.1[more]
SMESG000041940.10.000e+095.47SMESG000041940.1[more]
SMESG000041940.10.000e+096.99SMESG000041940.1[more]
SMESG000033045.11.067e-7127.62SMESG000033045.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30009463 ID=SMED30009463|Name=WD repeat-containing protein 49|organism=Schmidtea mediterranea sexual|type=transcript|length=3966bp
CTACTTTAAGGTTAACACAATTGCCTTGCCTCCCTTTGTAACTAATTTAA
AATATACGAATCTAAGAAATAATAAAAATAATGAATTTAAATCGATCTAA
AGAATCTCATACGCCATTAACTGAAAATAAGTTAGAACTAAAGTTAAATA
TAAAAGATTTAGAAACTTTACAAGAAGCATTTTTTATGGATGGTAGTCAT
AATCGTTCACAGCATTTCAATGGCGAAGAATTTGTTGAAGCATTAAGCCT
GGTTCTCTGTAAAGGAACTAGAGAAGAATATAGCGATTTATTCGATAAAA
TTGATATTACCAGAGAAGGATATGTTGACTGGGAAAAATTTGCTTCACAC
ATGCTTTTAGAATTTTATGAAAAGGATGATAGAACTAAATCATCATCTCT
GCCACAATGGAAAGAATTAAAAACGCTTTCTGGACCTCACAAAGATGTCA
TTCAAAGAATAGTGCTTGTTAGAAACCTTAACCGTTACCTCACAATCAGC
AAGGAAGGAAATGTTGGCTTGTGGGGTTCGGATTGTAAACTTCAGAAAGT
TGCCAAAACTCACACAGAAAGTTGTCGATCACGAGACTTATGGGTGACAG
ATTTTGCATTCTTAGGCAATGTTAATAAAGTTGCTGTTAGTTTCACAAGC
AAGGAAATCAGCTTTTACGATATGAATGTAAAACTTGAATTTAATTGCCA
GGTGAAATTGGAAAATTTGTTCAGAATTCCCATATGCATGGATTACTGGC
ATCATCCTGATAACAATGGGGAAGCGATAATGGCTTGGGGTGATACTGGA
GGTTATATAAATGTCATTTTATGGAGTAACATCAGTTCATCTCTGTTTGA
AAGAGTTTCCTCAAAGGCATCTGACAAAGATGAAAATACGATCATAATAT
CAATCAATGATATTATTCATGGTAGTATTAAAACATGCACTTATTTTTCT
CACAAAGCCCATCAAGATTGGGTTCGGAAAGTGTCATATATTCCAAATCT
CGAGTGTTTTGTAAGTTGCGCAACAAATTGGAACACTTCAATGGTTATAT
GCTGGATGGAAAAATACAATCCATCAAATTCAACTTCATCTGAAATGGCC
GGCATTCCAGAAAGTCGGGGATTCTCAAGAACATCATGTTTTACCGTCCA
CCAAGGCATCAATTCATTTGCTTACAATGAAAATCTCAACTTAATTGCTA
CGGCTGGAGTGAATTTTCAAGTTTGTCTGTGGAATCCTTATGTGATATCG
AAACCAAATGGGCTCTTGAGAGGACACATGGCTTCGGTAACAGATGTTCA
ATTTAACAAGGCTAGGGGTCATCTAATAAGTTTTTCAAAAGATAAAATAC
TTCGCATTTGGGATGTTCAATTGCAAGTCTGCATCCAGAGATATGCTGGC
GTATTTCCTAAAGGACAAGAAATGTACTCAAAAATGTTTTATCACGAAGA
AAAGTTGAGGCTGTTTATAACTTTCAATTTCGGACTGACAATGCTCGAAA
TGAAGCCCGATGTTAAAGACAAAATAAGTAGCCATGAAAAGCCTTTAATT
GGATGTCTTTATAATTCTCTGTACAACCAAGTTGTAACTGCTTGCCAGGG
AGGTATTATTTATTGTTGGATGGTTGATACTGGACAACGAGTAAAGACAA
TTACCGAAATTTGTGGTCCTCAAGCCGAATTGACTTGCATTACTCAAGAT
AGCACTCAAACTCGTTTGTACACAGGAGCCACCGATGGCAATGTTAAAAT
TTGGGATTTTAACGGCCACTGCTATAATACTTTAATTGTGGCTAATGGAA
ACCCCGTGGATATTAGTCAGATAGTGATTTTAAAGCGATGCGTTCTTGTT
TTTGGATTTTCCAAAAGCATAACAGCATTTTGGACAAGTAGCTTTAAAGA
TCATAAGGTTAGCCCGTCTCCTTGGAAGGGAGTTCAGACTCACAAAGATG
ACATTTTGTCCGGTGCATCCATTCCACCACACGCGGTTGCGACTGGCTCG
TACGATGGTGAAATAATAATTTGGAATATAAATTCTGAACAAGCTTCCCG
AACTATGACTCAAAGAAGTCAAGATGAGATGAAAGAAGTGAAAAAGCTAG
CAGAACAAACAATTGTGAGAATCAAAATGGCTGCAAACGCGGAGTTGAAA
AGGGCAGCCTCGAATTCGATTCAACAGGAAACTGATGATAAACTAGATTT
TATTAAAGCTGAAATTCAAAATTCAATTGCAAATCGTCAAATTGAGGAAT
CCATTACAACTTCGACAAGTAGTGAAGAAACTTCAACGTCTTCATCAACA
GATACTGTTTCTGATATGCAAGTGCAATATAAAAAAATGGACGTCATGTT
TAATATTTCGCGATTGATTTATCTGGAATCTCGCAAAAAAATTAAGCATG
GAGGAGGGGCAAATTTAATTTCATGTGGAGGCAATGGAATTGTGAGATTT
TGGAATTCGGCTGAAGGTTGGCTTATTGGGGAATTTGTTGCTCATGAAAA
TGCTAGTAATATTATTATGAATACTGATGTCTCGAACCAATATCTGGTAA
CCGGTGATATGGACGGATATATAAGGGTTTGGGATATACTCAGTTATTGC
CAAACAGAAAGTGAAAATCAAAAAATAATGAGTCCTCCAACATTAATCAG
CCAATGGCAAAGCCATTCTGATGAAATCAGTGGAATCTCATTTTGCTTCA
AATTCAGTCGGACATTGATTATAACTAGCTCGGCTGACCAATCGGCTGCT
TTGTGGGAATTGAATGGTGTTCTTATTGGCCGATTTGGACAAGAGCATCG
ATGGAAACTAGGATCTATTATTGAAACTCCAACAATTGCTGCTATTGAAA
CTCATGAAGATGAAGTTGTAAAGCAAGAAGAGGACAAGTATAAGGTTGAC
CCGAATTGGTATCCCGATCCAGAAGCTATTCAAAATCCCTCTGGATACAG
AATTAATACATGGAAGGATACAAATCTTGGAAAAGATTACCAGGAACTCC
GAGTTCGTAAAAGGGAACGCATTCAACCATCATCGATTCCAGATCTTCCT
TATTTATATGGTGAAAAAATTGGTAGACCAACATTTGGTCCATTTTATTC
ATTAAATATATCAAGTTTCGAAGAAATTGAAGACATAGAACAACCGGAAT
TTATGGAATATCCTGAAAAGTTTTTTAATGAAACTGAAGAATTTTTAACC
AAGACAGCAAGGGTTCCTCTTCTCAATGAAACTCTGAAAGCTGTATTCGA
CGAAAGATCTCTTTTACCAGAATATATTTTGGAATTTGAACATAAATTCC
GGAATAGATTCCAGCGACATTTATCAGAGGCCAAAGTCAAATTGTCATTA
GACGATTCCAATAGTTTCCAAGAACAATTACCTCGAAAAGCTAAAACAGT
TAGATTGAAGCCAATTCAGGAAGGTTCAAAATATCAGAAAAAATTAATGC
ATAAGCTTCATATTAAATAATATTTTTCATGTTTATGATTAATGTTAAGA
TTAAAAGTATGAGCGGAAATTTTCTTTCATTAATTTCTCTCTTTTTTTCA
ATTGTAATACATCATTTTCAAAATGAATCTGCTATTTGTGTGACAAATTT
TGTGTTTGTATAGAAAATACACCAAAATGCAAATAACTCAAAATTGTATA
CTCATTTATCCCATTTAATAAGTGTAAATAAAGCCAGATATATTTCACAT
TTGTATCATGGTTCTGACTGTATGTTACTAATTTAACAGATCTTATGCAA
CAATGTTGTCTATAATATAGGTAGATTTATAATAGAATAGATGACTCGTA
ATTGCTAACAAGTCATTTTTTTCAAAATATGAATTTACAAAATTGTTTAT
TATCTAGTAATGTGGTTAATAACAATTGTTATTATTAATAATTTATTATT
AATTATTAATAAAAAACAGAACAATTAAGAAATTACATAATGCAATATTG
CTTTCATTACTATCCT
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protein sequence of SMED30009463-orf-1

>SMED30009463-orf-1 ID=SMED30009463-orf-1|Name=SMED30009463-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=1130bp
MNLNRSKESHTPLTENKLELKLNIKDLETLQEAFFMDGSHNRSQHFNGEE
FVEALSLVLCKGTREEYSDLFDKIDITREGYVDWEKFASHMLLEFYEKDD
RTKSSSLPQWKELKTLSGPHKDVIQRIVLVRNLNRYLTISKEGNVGLWGS
DCKLQKVAKTHTESCRSRDLWVTDFAFLGNVNKVAVSFTSKEISFYDMNV
KLEFNCQVKLENLFRIPICMDYWHHPDNNGEAIMAWGDTGGYINVILWSN
ISSSLFERVSSKASDKDENTIIISINDIIHGSIKTCTYFSHKAHQDWVRK
VSYIPNLECFVSCATNWNTSMVICWMEKYNPSNSTSSEMAGIPESRGFSR
TSCFTVHQGINSFAYNENLNLIATAGVNFQVCLWNPYVISKPNGLLRGHM
ASVTDVQFNKARGHLISFSKDKILRIWDVQLQVCIQRYAGVFPKGQEMYS
KMFYHEEKLRLFITFNFGLTMLEMKPDVKDKISSHEKPLIGCLYNSLYNQ
VVTACQGGIIYCWMVDTGQRVKTITEICGPQAELTCITQDSTQTRLYTGA
TDGNVKIWDFNGHCYNTLIVANGNPVDISQIVILKRCVLVFGFSKSITAF
WTSSFKDHKVSPSPWKGVQTHKDDILSGASIPPHAVATGSYDGEIIIWNI
NSEQASRTMTQRSQDEMKEVKKLAEQTIVRIKMAANAELKRAASNSIQQE
TDDKLDFIKAEIQNSIANRQIEESITTSTSSEETSTSSSTDTVSDMQVQY
KKMDVMFNISRLIYLESRKKIKHGGGANLISCGGNGIVRFWNSAEGWLIG
EFVAHENASNIIMNTDVSNQYLVTGDMDGYIRVWDILSYCQTESENQKIM
SPPTLISQWQSHSDEISGISFCFKFSRTLIITSSADQSAALWELNGVLIG
RFGQEHRWKLGSIIETPTIAAIETHEDEVVKQEEDKYKVDPNWYPDPEAI
QNPSGYRINTWKDTNLGKDYQELRVRKRERIQPSSIPDLPYLYGEKIGRP
TFGPFYSLNISSFEEIEDIEQPEFMEYPEKFFNETEEFLTKTARVPLLNE
TLKAVFDERSLLPEYILEFEHKFRNRFQRHLSEAKVKLSLDDSNSFQEQL
PRKAKTVRLKPIQEGSKYQKKLMHKLHIK*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000016pharynx
PLANA:0000020protonephridia
PLANA:0000034epidermis
PLANA:0000099neuron
PLANA:0000418head
PLANA:0002032epidermal cell
Vocabulary: INTERPRO
TermDefinition
IPR036322WD40_repeat_dom_sf
IPR020472G-protein_beta_WD-40_rep
IPR001680WD40_repeat
IPR011992EF-hand-dom_pair
IPR015943WD40/YVTN_repeat-like_dom_sf
IPR019775WD40_repeat_CS
IPR017986WD40_repeat_dom
IPR011047Quinoprotein_ADH-like_supfam
Vocabulary: molecular function
TermDefinition
GO:0005515protein binding
GO:0005509calcium ion binding
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR020472G-protein beta WD-40 repeatPRINTSPR00320GPROTEINBRPTcoord: 822..836
score: 35.13
coord: 546..560
score: 34.24
coord: 415..429
score: 37.51
IPR001680WD40 repeatSMARTSM00320WD40_4coord: 347..385
e-value: 0.067
score: 22.3
coord: 517..559
e-value: 6.5E-4
score: 29.0
coord: 729..792
e-value: 260.0
score: 1.7
coord: 109..149
e-value: 42.0
score: 6.8
coord: 151..197
e-value: 35.0
score: 7.2
coord: 795..835
e-value: 0.16
score: 21.1
coord: 389..428
e-value: 0.0017
score: 27.7
coord: 611..649
e-value: 1.2
score: 16.6
coord: 284..326
e-value: 12.0
score: 10.1
coord: 475..514
e-value: 8.4
score: 11.2
coord: 852..893
e-value: 0.083
score: 22.0
IPR001680WD40 repeatPFAMPF00400WD40coord: 393..428
e-value: 0.0044
score: 17.8
coord: 797..835
e-value: 0.0026
score: 18.6
coord: 533..559
e-value: 0.16
score: 12.9
IPR001680WD40 repeatPROSITEPS50082WD_REPEATS_2coord: 618..658
score: 9.673
IPR001680WD40 repeatPROSITEPS50082WD_REPEATS_2coord: 527..561
score: 9.573
IPR001680WD40 repeatPROSITEPS50082WD_REPEATS_2coord: 396..430
score: 13.048
IPR001680WD40 repeatPROSITEPS50082WD_REPEATS_2coord: 818..836
score: 9.372
NoneNo IPR availableGENE3DG3DSA:1.10.238.10coord: 8..128
e-value: 3.8E-5
score: 25.3
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 721..744
NoneNo IPR availablePANTHERPTHR44324FAMILY NOT NAMEDcoord: 19..1087
NoneNo IPR availablePANTHERPTHR44324:SF1WD REPEAT-CONTAINING PROTEIN 49coord: 19..1087
IPR015943WD40/YVTN repeat-like-containing domain superfamilyGENE3DG3DSA:2.130.10.10coord: 473..703
e-value: 2.7E-18
score: 67.7
IPR015943WD40/YVTN repeat-like-containing domain superfamilyGENE3DG3DSA:2.130.10.10coord: 223..441
e-value: 9.8E-16
score: 59.5
IPR015943WD40/YVTN repeat-like-containing domain superfamilyGENE3DG3DSA:2.130.10.10coord: 735..935
e-value: 3.5E-17
score: 64.1
IPR019775WD40 repeat, conserved sitePROSITEPS00678WD_REPEATS_1coord: 546..560
IPR019775WD40 repeat, conserved sitePROSITEPS00678WD_REPEATS_1coord: 636..650
IPR019775WD40 repeat, conserved sitePROSITEPS00678WD_REPEATS_1coord: 822..836
IPR019775WD40 repeat, conserved sitePROSITEPS00678WD_REPEATS_1coord: 880..894
IPR019775WD40 repeat, conserved sitePROSITEPS00678WD_REPEATS_1coord: 779..793
IPR017986WD40-repeat-containing domainPROSITEPS50294WD_REPEATS_REGIONcoord: 353..658
score: 15.004
IPR017986WD40-repeat-containing domainPROSITEPS50294WD_REPEATS_REGIONcoord: 779..902
score: 12.183
IPR036322WD40-repeat-containing domain superfamilySUPERFAMILYSSF50978WD40 repeat-likecoord: 105..441
IPR036322WD40-repeat-containing domain superfamilySUPERFAMILYSSF50978WD40 repeat-likecoord: 357..893
IPR011992EF-hand domain pairSUPERFAMILYSSF47473EF-handcoord: 6..96