TIR domain-containing protein

BLAST of TIR domain-containing protein vs. TrEMBL
Match: A0A210PZ21 (Vacuolar protein 8 OS=Mizuhopecten yessoensis OX=6573 GN=KP79_PYT23907 PE=4 SV=1)

HSP 1 Score: 192.2 bits (487), Expect = 1.366e-47
Identity = 174/698 (24.93%), Postives = 332/698 (47.56%), Query Frame = 1

Query:  103 TIDEINLKICSEAEDIINKVKSL--QKFITDLQPQE-SSEFQQIVKAINSKYFSLNKFNVKLEDVKRLRLSNANVLIKLDIFNIYYTILVQILHNVFGKNYSEEIDNKFHSAIKNLIDIFFNYTDASSDFGKEFCKNDKLLHLYYKIISEFKENCLNKSLSKN--ITDLLRICIST----LYNTMLHDVNENYTIIKEMKFLDLIKDLMKCEEGKIKRAALLFVAYIADETESKMFKSDLHSISYLIELLKKSLNTRFSRSQGLSTEELSKGIGKLSKNDENKQLLVEMGILPVLKMQLEKDDKRNQELALGVLWSLTFDEKNK--ILIQKEFR--NKILELKTKLDKKCQAGLTHDTAGSQVPTLQTHSVESRAKSCNRIPKVIGNLESKKDMNSVSYDDFLCFETQFDENTEEISKNSFNYKNILDGLTWTLTNLEEVKSKKQETEEEEVATKDHIMLSYSWSNADIVMKIYDCLVNKGFKLWIDKYXXXXXXXXXXXXAQAIQNSYAVVIFISQNYKNSDNCRAEAQYAISKKKPVIPVMVQEKYRPDGWLGICIIGLQYCDFAGRYNFE-------------------DAXXXXXXXXXXXXAGNVQKKIDEIDHIDPVH--VKNQSKNNQD-ITKWANERCKNWFDE--IGIKRIVWPKHYTGNELDFLRTISQVPGEVFYQISKNELKITDL 2085
            T +EI  KI    ED ++  + L  Q  + D +  + S+ F++I       +F +  F++ ++D    +     +++  ++   +  ++V IL + + +     +D +    + N   +  N+TD   +       + + L      ++E  +  +N  L+ +    D +R+ IS+     +N  + D N N   ++ + F+DL+   +   + K + +A+  +A I DE +S++ ++D+  + ++   L +++  +  R  G S +EL++ + ++++ND NK+ LVE GILP L    E +D   Q  A+G +W+L+FD++N+  +++  E +  +  + LK   DK+ +                        K+CN      G L + +                  EN  +    S NYK+I +  T    +   V +++++    EV ++ HIM+SY W+N  I+ KI D L   GFK+W+D      E + +++MA+A++N+  V++  SQ YK+SDNCRAEA+YA  KKK VIP+ ++  Y PDGWLG       + DF G+Y+FE                   D +++         A   ++ + E  +  P H  V + +    + + KW ++    W  +  +  +++   K  TG E+ FL  +     + FY++  + LKIT+L
Sbjct:  144 TEEEIKEKINKTFEDALHTWEPLSDQSRLVDAETGKCSAAFRRISNNTFLYHFRMKAFSLSIQD--EFKSDYYRLMVTENVVPKFCDMVVYILKHGY-EAEDGTMDAEMFKPLSNTFGLLTNFTDNKIERADIVADHPEFLMC----LAENFKKWMNPYLAGDQIREDQIRVAISSPLSIFHNIAMQDRNINR--MRSLGFVDLLTPFVSSPKEKTRLSAVATLADIVDEKQSEIIRTDVGVMKFIKNSLARAMKEKSRRIFGWSPQELARTVRRIARNDANKRALVEQGILPPLVKLAESEDMEEQREAVGAMWTLSFDKENQKDMILDTECKPVDTFIRLKNSPDKEVR------------------------KTCN------GALWTMR------------------ENLAQ----SENYKDIRERYTSPQPSPAHVATERRQ----EVKSEGHIMISYQWANQAILKKIRDNLRANGFKVWMD--IDDMEGSTLDAMARAVENADVVLVCYSQKYKDSDNCRAEAEYAFQKKKKVIPLKMELNYIPDGWLGFICGAKLFFDFGGKYSFESRVEGLVKELWSKMSKDVVDGVVVPESATVVYSAPVAKENVAEPVYSAPPHGGVSHVTMTTVELVKKWKDQDVDKWMAKHSLSTQQV---KKMTGVEVAFLMLLKTESPDFFYKVLTDTLKITNL 771          

BLAST of TIR domain-containing protein vs. TrEMBL
Match: A0A1S3HGA3 (uncharacterized protein LOC106155047 OS=Lingula unguis OX=7574 GN=LOC106155047 PE=4 SV=1)

HSP 1 Score: 188.348 bits (477), Expect = 6.226e-47
Identity = 143/553 (25.86%), Postives = 258/553 (46.65%), Query Frame = 1

Query:  448 IFFNYTDASSDFGKEFCKNDKLLHLYYKIISEFKENCLNKSL---SKNITDLLRICISTLYNTMLHDVNENYTIIKEMKFLDLIKDLMKCEEGKIKRAALLFVAYIADETESKMFKSDLHSISYLIELLKKSLNTRFSRSQGLSTEELSKGIGKLSKNDENKQLLVEMGILPVLKMQLEKDDKRNQELALGVLWSLTFDEKNKILIQKEFRNKILELKTKLDKKCQAGLTHDTAGSQVPTLQTHSVESRAKSCNRIPKVIGNLESKKDMNSVSYDDFLCFETQFDENTEEISKNSFNYKNILDGLTWTLTNLEEVKSKKQETEEEEVATKDHIMLSYSWSNADIVMKIYDCLVNKGFKLWIDKYXXXXXXXXXXXXAQAIQNSYAVVIFISQNYKNSDNCRAEAQYAISKKKPVIPVMVQEKYRPDGWLGICIIGLQYCDFAGRYNFE-DAXXXXXXXXXXXXAGNVQKKIDEIDHIDPVHVKNQSKNNQDITKWANERCKNWFDEIGIKRIVWPKHYTGNELDFLRTISQVPGEVFYQISKNELKITDLKDL 2094
            IF+NY+DAS  F +    +  L ++   +     +  +  S+    +  +  L+  I  ++N     V+    I  EMK +D +K  +   E + K  A++  AYI ++ ++ +  ++     ++I+LLK++L +   R++G S  E++KG+G +++ND+NK L+ E G +P L   L  +D+   E AL  LW L FD+ NK  IQ+E               C           +V  L  H      K+ N +  ++         N +S +D L  + + D  +                          ++ K   T     A   H+M+SY+W +  +++K+ D L  +GF +W+D        + +++MA+A++N+  V+I +S  YK+S NCR EA+Y+    K ++P+M+Q  Y+PDGWLG+ +    + DF+G+YNFE     L  +   R K G +   + E   + P          ++ + W  E    W ++  + R+      TG ++ FL+ I     E F+    +++ I  L+DL
Sbjct:  153 IFWNYSDASLKFAESVGLSGYLEYMMNDL-DAIDKGVIAGSIDTEEEGTSLALKSAIGCVHNCA--KVDTLRPIFHEMKVVDRLKPYLHTAETENKAVAIMTEAYIINDEQNDILATEDGIFEFIIDLLKQALESDDHRAEGFSAWEMAKGLGAMARNDQNKTLIAEKGAIPFLAAMLASEDEEEVEEALSTLWKLGFDQNNKRKIQEE-------------PNCF---------ERVKGLTKHKNSRITKAANGVVWILSQ-------NQLSSEDVLQSQARTDSAS--------------------------LREKSASTAAGGKA--GHVMISYNWGDQKVLLKVKDELRRRGFNIWMD--VEQMGGSTLQAMAEAVENAAVVLICMSDRYKDSPNCRTEAEYSFKLNKDIVPLMMQRNYKPDGWLGMILGSKLFFDFSGKYNFECKVDELAKELGNRGKTGGIVPVMTETAALAPSF----GSGKKNPSHWNKEDVAQWLEKNNLNRMPKFTKLTGEQIAFLKEIHTNAPEFFFCYMTDKMGIVQLQDL 639          

BLAST of TIR domain-containing protein vs. TrEMBL
Match: C3YBW8 (Uncharacterized protein OS=Branchiostoma floridae OX=7739 GN=BRAFLDRAFT_130981 PE=3 SV=1)

HSP 1 Score: 179.874 bits (455), Expect = 7.587e-43
Identity = 148/570 (25.96%), Postives = 273/570 (47.89%), Query Frame = 1

Query:  385 GKNYSEEIDNKFHSAIKNLIDIFFNYTDASSDFGKEFCKNDKLLHLYYKIISEFKENCLNKSLSKNITD--LLRICISTLYNTMLHDVNENYTIIKEMKFLDLIKDLMKCEEGKIKRAALLFVAYIADETESKMFKSDLHSISYLIELLKKSLNTRFSRSQGLSTEELSKGIGKLSKNDENKQLLVEMGILPVLKMQLEKDDKRNQELALGVLWSLTFDEKNKILIQKEFRNKILELKTKLDKKCQAGLTHDTAGSQVPTLQTHSVESRAKSCNRIPKVIGNLESKKDMNSVSYDDFLCFETQFDENTEEISKNSFNYKNILDGLTWTLTNLEEVKSKKQETEEEEVATKDHIMLSYSWSNADIVMKIYDCLVNKGFKLWIDKYXXXXXXXXXXXXAQAIQNSYAVVIFISQNYKNSDNCRAEAQYAISKKKPVIPVMVQEKYRPDGWLGICIIGLQYCDFAGRYNFEDAXXX--XXXXXXXXXAGNVQK-KIDEIDHIDPVHVKNQSKNNQDITKWANERCKNWFDEIGIKRIVWPKHYTGNELDFLRTISQVPGEVFYQISKNELKIT 2079
            G  + +E   + + AI+N     ++++DAS +F K   K      L+  +I + K+    K+   N     L+R  +  L+N     V EN  I++ +  +D +   +   + ++K   ++ +AYI  E ++ +  +D   IS+++ + ++++++   RSQG S  E++ GI +L++ND+NK ++V+ G LP+L   +E  D+  QE     +W L F + NK  I+ E R  + +LK   D K Q   T   A   +  L   + E +AK             S++D+   S    +    Q+D     + + +                    KS++   E+ +  +  HIM+SY W +   ++K+ D L + G+++W+D        + +++MA+A++NS  V+I +SQ YK S NCR EA+Y    +K ++P+M++ KY+PDGWLG  +    Y DF+ ++ FED++         +   A  VQK +  E+       +         +  W      NW  E  +++    +  TG +L FL+++    GE+ +    N  K T
Sbjct:  145 GNMFDDETVWECYYAIRNCC---WSFSDASFNFAKRLGKAG----LFPMLIEDLKQ--YKKTFQTNQAHNWLVRCSLGILHNCA--KVMENRAILRPLGLIDQLLPWINTSDEELKTVTVMTLAYIVGEEDNDLIMADDSVISFIMTVFEEAVDSELMRSQGFSAMEMAMGISQLAQNDDNKVMIVKKGALPLLVQLMETGDEEEQEQGANAVWQLAFHDDNKDKIRAEPR-LMYQLKRLKDSKNQE--TAKAANGALWVLDKQAREEKAKEL----SEKSEESSREDLQEGSGPHIM-ISYQWDHQKTLVKEKAKELS---------------EKSEESSIEDLQEGSGPHIMISYQWDHQKTLVKVKDRLQSYGYRVWMD--LEQMGGSTLQAMAEAVENSVVVLICMSQKYKESPNCRTEAEYTFQLRKQIVPLMMEGKYKPDGWLGAILGAKLYFDFSAQHKFEDSIGKLIKELGQRGRSAQLVQKVQAVEVGAGGAGALPIMPPAKPRVLDWKQAEVDNWIAENQLEKNFL-RELTGPQLHFLQSLR---GEIGFYAPSNHSKST 674          

BLAST of TIR domain-containing protein vs. TrEMBL
Match: V4AY29 (TIR domain-containing protein OS=Lottia gigantea OX=225164 GN=LOTGIDRAFT_230877 PE=4 SV=1)

HSP 1 Score: 172.17 bits (435), Expect = 1.629e-42
Identity = 147/525 (28.00%), Postives = 253/525 (48.19%), Query Frame = 1

Query:  616 LYNTMLHDVNENYTIIKEMKFLDLIKDLMKCEEGKIKRAALLFVAYIADETESKMFKSDLHSISYLIELLKKSL--NTRFSR-SQGL--STEELSKGIGKLSKNDENKQLLVEMGILPVLKMQLEKDDKRNQELALGVLWSLTFDEKNKILIQKEFRNKILELKTK---LDKKCQAGLTHDTAGSQVPTLQTHSVESRAKSCNRIPKVIGNLESKKDMNSVSYDDFLCFETQFDENTEEISKNSFNYKNILDGLTW--TLTNLEEVKSKKQ-ETEEEEVATKDHIMLSYSWSNADIVMKIYDCLVNKGFKLWIDKYXXXXXXXXXXXXAQAIQNSYAVVIFISQNYKNSDNCRAEAQYAISKKKPVIPVMVQEKYRPDGWLGICIIGLQYCDFAGRYNFE---DAXXXXXXXXXXXXAGNV-----QKKIDEIDHID----PVH-------VKNQSKNNQDITKWANERCKNWFDEIGIK--RIVWPKHYTGNELDFLRTISQVPGEVFYQISKNELKITDLKDL 2094
            ++N  + D N    +++E+KF  ++K+ +      IK  A+L +A I  E ES   +++   I +L+   K++L  ++R ++   G+     EL+KGIG+L+ ND NK+LLVE G LP+L    + DD   Q+ AL  +W+L F+E+N        ++KI+EL      LD K + G +                                     D  S  Y       T+  ++++        +K I D L    T++  +    K + ET E++   K H+M+SY W + +I+ ++ D +     K+W+D      E + +++MA A++N+  V+I +S+ YK+S NCRAEA+YA   +K VIP++++  Y+PDGWLG+ +    + DF+G+Y FE   + L+  + Q   +  G V      K +D +D  D    PV         K       ++  W   + K+W  + G+   R+   +  TG E+ FL+ +     E +Y   K +L I  L D+
Sbjct:    3 IHNVAMTDAN--IPLLQELKFAPVLKNYLSFTNDTIKLTAILGLADIMTEEESHYVETNNEVIIFLLMTFKRALFASSRTAKDGNGMIWGVLELAKGIGRLASNDGNKKLLVEKGSLPLLLKLAKSDDLEEQKEALKSMWALAFNEEN--------QDKIIELPGLIEFLDDKNRTGFS-------------------------------------DTRSTCYGILWTMRTKLQQSSQ--------FKAIGDRLVVKKTMSPSKTFTEKGELETSEKDSKNKGHVMISYQWGDQEILKRVRDKIRGSKKKVWMD--IDDMEGSTLQAMADAVENADIVLICMSRKYKDSPNCRAEAEYAHQLRKTVIPLIMERSYKPDGWLGMILGAKLFYDFSGKYPFESKIEGLLREISQKLNLGDGAVAGPTGSKGVDVVDGPDQKIVPVQNDMVYAPYKAPPPKLGEVKSWNAAQVKDWLKKYGLSGTRV---EKLTGREIAFLQKLQASTPEYYYMTVKTDLGIKTLTDM 467          

BLAST of TIR domain-containing protein vs. TrEMBL
Match: W4XMC6 (TIR domain-containing protein OS=Strongylocentrotus purpuratus OX=7668 PE=4 SV=1)

HSP 1 Score: 164.081 bits (414), Expect = 1.395e-39
Identity = 125/435 (28.74%), Postives = 209/435 (48.05%), Query Frame = 1

Query:  484 GKEFCKNDKLLHLYYKIISEFKENCLNKSLSKNITDLLRICISTLYNTMLHDVNENYTIIKEMKFLDLIKDLMKCEEGKIKRAALLFVAYIADETESKMF-KSDLHSISYLIELLKKSLNTRFSRSQGLSTEELSKGIGKLSKNDENKQLLVEMGILPVLKMQLEKDDKRNQELALGVLWSLTFDEKNKILIQKEFRNKILELKTKLDKKCQAGLTHDTAGSQVPTLQTHSVESRAKSCNRIPKVIGNLESKKDMNSVSYDDFLCFETQFDENTEEISKNSFNYKNILDGLTWTLTNLEEVKSKKQETEEEEVATKDHIMLSYSWSNADIVMKIYDCLVNKGFKLWIDKYXXXXXXXXXXXXAQAIQNSYAVVIFISQNYKNSDNCRAEAQYAISKKKPVIPVMVQEKYRPDGWLGICIIGLQYCDFAGRYNFED 1785
            G  + K   ++ L Y I+ E +E  L +   K  T L     + L+N  L     N  + +E K ++ ++  ++ +   +K  +++ +AYI +E + ++  +   ++I YL+E+LK + N++  R QGLS EE++  +G+L+ +D NK  +VE G LP++   L  +    QE +   +W+L F +     + ++ R+         +  C   L           L T S    AK+ N    VI     KKD+   + DD                                 T L    S+KQ           HIMLSY W    +V+K+ D L   G+ +W+D        + +++MA+AI+N+ A+V+ +S+ YK S NCR EA+YA   +K +IPVM++E Y+PDGWLGI +    Y DF+GR + E+
Sbjct:    7 GDPYLKAVSMMTLAY-IVEEGQEEILAE---KGTTSL-----NILHN--LAKAPGNKHVYREEKVVESMEPFLEGDP-YLKAVSMMTLAYIVEEGQEEILAEKGTNTIEYLVEILKDAQNSKDKRCQGLSVEEVTAALGRLAVHDNNKYKIVEAGGLPLMISMLHDESVETQEASAHAVWNLAFSDD----VSEKLRS---------NTDCMMALQ---------DLSTSSSSEVAKAANGALWVINKEGEKKDLVKENEDD---------------------------------TGLGHSLSRKQ----------PHIMLSYQWGCQPLVLKMRDVLAKAGYNIWVD--VDCMYGSTLQAMAEAIENACAIVMCMSERYKESPNCRTEAEYAFQLRKRIIPVMMEEYYQPDGWLGIILGAKFYMDFSGRLDIEE 362          

BLAST of TIR domain-containing protein vs. Ensembl Nematostella
Match: EDO45030 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RU69])

HSP 1 Score: 108.612 bits (270), Expect = 2.255e-24
Identity = 73/260 (28.08%), Postives = 133/260 (51.15%), Query Frame = 1

Query: 1348 GLTWTLTNLEEVKSKKQETEEEEVAT---KDHIMLSYSWSNADIVMKIYDCLVNKGFKLWIDKYXXXXXXXXXXXXAQAIQNSYAVVIFISQNYKNSDNCRAEAQYAISKKKPVIPVMVQEKYRPDGWLGICIIGLQYCDFAGRYNF--EDAXXXXXXXXXXXXAGN---VQKKIDEIDHIDPVHVKNQSKNNQDITKWANERCKNWFDEIGIK---RIVWPKHYTGNELDFLRTISQVPGEVFYQISKNELKITDLKDL 2094
            G+ W      E++ K+  T +E  A    ++H+M+SY W     ++++   L   G+++W+D        + +++MA A++N+  V++ +SQ YK S NCR+EA+YA   +K ++P+M+++ YRPDGWLG+ +    + DF+ +     +D+   L K+I     G    V+ K+  + H D V V  +     DI+KW+ +   NW +  G++         H +G  L  L  +     E FY   K +     L+++
Sbjct:  572 GVLW------EIEGKESHTVKESTADEPLRNHVMISYQWDVQPTMIQVKSKLQAAGYRVWMD--LEQMGGSTLQAMANAVENAEVVLMCVSQKYKESPNCRSEAEYAFQLRKDIVPLMMEKSYRPDGWLGMIMGAKLWIDFSDKQTLRVDDSFEKLQKEIGMRGRGRGNVVESKLVAVQH-DVVDVFPKI----DISKWSKDDVMNWMNGFGLRLGNDSTIASHLSGKLLQRLAKLRSESPEFFYSSVKQDFGFAHLQEV 818          

HSP 2 Score: 70.4774 bits (171), Expect = 1.710e-12
Identity = 55/201 (27.36%), Postives = 103/201 (51.24%), Query Frame = 1

Query:  607 ISTLYNTMLHDVNENYTIIKEMKFLDLIKDLMKC---EEGKIKRAALLFVAYIADETESKMFKSDLHSISYLIELLKKSLNTRFSRSQGLSTEELSKGIGKLSKNDENKQLLVEMGILPVLKMQLEKDDKRNQELALG--VLWSLTFDEKNK--ILIQKEFRNKILELKTKLD---KKCQAGLTHDTAGSQVPTLQTHSVE 1179
            ++T   TM H+++      +  K  D +K L+     E  +    ALL +AY+ DE+ + +  +    I +LI +L KS ++  +R  G +  EL++G+ +++ ND NK+L+ + G +P+L + +  + K +++   G   LW L FD +NK  IL        + EL+   D   KK  AG+  +  G +  T++  + +
Sbjct:  393 LNTAMGTM-HNLSRRIPCRQYFKKADTVKVLLPMLNDEVSQFAAKALLILAYLTDESNNSLIMASEEPIQFLIHILSKSCSSNSNRYLGFTNSELAEGLSQIAVNDSNKKLIGQHGAIPIL-VDMLANAKNDEQRRCGAEALWVLAFDNENKEAILTTPNAVELLKELQHSEDDSVKKAAAGVLWEIEGKESHTVKESTAD 591          

BLAST of TIR domain-containing protein vs. Ensembl Nematostella
Match: EDO41008 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S5P1])

HSP 1 Score: 105.531 bits (262), Expect = 3.112e-23
Identity = 48/110 (43.64%), Postives = 76/110 (69.09%), Query Frame = 1

Query: 1432 HIMLSYSWSNADIVMKIYDCLVNKGFKLWIDKYXXXXXXXXXXXXAQAIQNSYAVVIFISQNYKNSDNCRAEAQYAISKKKPVIPVMVQEKYRPDGWLGICIIGLQYCDF 1761
            H+MLSY W   D+V+K+ D L   G+K+WID      E + +E+MA A++N+ AV++ +S+ YK S NCR+EA+Y+   +K +IP+M++ +Y+PDGWLGI +    + DF
Sbjct:  554 HVMLSYQWGYQDVVLKVRDELRAAGYKVWID--VEQMEGSTLEAMASAVENAAAVLMCVSRAYKESPNCRSEAEYSFQLRKDIIPLMMEPQYKPDGWLGIIVGAKLWMDF 661          

HSP 2 Score: 103.605 bits (257), Expect = 1.424e-22
Identity = 64/229 (27.95%), Postives = 119/229 (51.97%), Query Frame = 1

Query: 1423 TKDHIMLSYSWSNADIVMKIYDCLVNKGFKLWIDKYXXXXXXXXXXXXAQAIQNSYAVVIFISQNYKNSDNCRAEAQYAISKKKPVIPVMVQEKYRPDGWLGICIIGLQYCDFAGRYNFEDAXXXXXXXXXXXXAGNVQKKIDEI------------DHIDPVHVKNQSKNNQDITKWANERCKNWFDEIGIKRI-VWPKHYTGNELDFLRTISQVPGEVFYQISKNEL 2070
            ++ HIM+SY W N   ++ +   L   G K+W+D        + +E+MA+A++N+  ++I +SQ Y++S NCR+EA+YA  ++K ++P+M+++ YRPDGWLG+ +    + DF  R + +  ++ L+K+++  +   +Q+  D +            D  D         +  D++KW  E    W  +IG+       K   G+ L  L  + Q   E +Y   K ++
Sbjct: 1010 SQQHIMISYQWDNQKAMLAVNKRLKEAGHKVWMD--VEQMGGSTLEAMARAVENASVILIAMSQRYQDSPNCRSEAEYAFQRRKKIVPLMMEQDYRPDGWLGMILGAKLWMDF--RESVDTGIVHLMKELQYNQTAALQQPHDPVTVDTTTVISSPPDKEDGPPGPTDVVDRPDVSKWKKEDVAKWLSDIGLSSSNKVRKKLDGSMLILLYRLKQESPEFYYASVKKDM 1234          

HSP 3 Score: 58.151 bits (139), Expect = 1.151e-8
Identity = 37/125 (29.60%), Postives = 70/125 (56.00%), Query Frame = 1

Query:  697 LMKCEEGKIKRAALLFVAYIADETESKMFKSDLHSISYLIELLKKSLNTRFSRSQGLSTEELSKGIGKLSKNDENKQLLVEMGILPVLKMQLEKDDKRNQELALGV--LWSLTFDEKNKILIQKE 1065
             MKC        ALL +AY+ DE  + +  +D   I++L+ +L  +++    +  G +  E++ GIG+++ ND+NK+L+     + +L   L K+ K + E   G+  L+ L+FD +NK ++ K+
Sbjct:  846 FMKCGVTYFVMNALLCLAYLVDERNNDLIMADEEPITFLLRMLSSAISDSRRQHLGFAAWEIACGIGRVASNDKNKRLIGRHDGVSILST-LVKEAKNDAERVYGLQALYMLSFDGENKKILCKD 969          

BLAST of TIR domain-containing protein vs. Ensembl Nematostella
Match: EDO39316 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SAI7])

HSP 1 Score: 80.8777 bits (198), Expect = 1.464e-16
Identity = 43/123 (34.96%), Postives = 67/123 (54.47%), Query Frame = 1

Query: 1432 HIMLSYSWSNADIVMKIYDCLVNKGFKLWIDKYXXXXXXXXXXXXAQAIQNSYAVVIFISQNYKNSDNCRAEAQYAISKKKP----VIPVMVQEKYRPDGWLGICIIGLQYCDFAGRYNFEDA 1788
            H+MLSY W   D+V K+YD L   G ++W+D +      ++  SMA+ +  +  +  F+S  Y  S NC+ E  YA  K       ++PVM ++ ++  GWLGI   GL + DF    NFE++
Sbjct:    3 HVMLSYQWDIQDLVKKVYDGLRAYGIRVWMDIH-GGIRGDINGSMAKGVDGAAILCCFMSTKYSESKNCKKELSYADGKTGCEEVIIVPVMCEKGFKAKGWLGIITAGLLWIDFRDEANFENS 124          

BLAST of TIR domain-containing protein vs. Ensembl Nematostella
Match: EDO33720 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SRG5])

HSP 1 Score: 72.7886 bits (177), Expect = 4.703e-16
Identity = 30/66 (45.45%), Postives = 49/66 (74.24%), Query Frame = 1

Query: 1567 AQAIQNSYAVVIFISQNYKNSDNCRAEAQYAISKKKPVIPVMVQEKYRPDGWLGICIIGLQYCDFA 1764
            A A++NS  V++  S+ YK+S N R+EA+YA ++KKP++P+M++  Y+PDGWLG+ +    Y +FA
Sbjct:   10 ANAVENSAVVLMCASRKYKDSVNYRSEAEYAYTQKKPIVPLMMENGYKPDGWLGMIMGSKLYFNFA 75          

BLAST of TIR domain-containing protein vs. Ensembl Nematostella
Match: EDO33105 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7ST59])

HSP 1 Score: 56.225 bits (134), Expect = 4.358e-8
Identity = 29/83 (34.94%), Postives = 47/83 (56.63%), Query Frame = 1

Query: 1435 IMLSYSWSNADIVMKIYDCLVNKGFKLWIDKYXXXXXXXXXXXXAQAIQNSYAVVIFISQNYKNSDNCRAEAQYAISKKKPVI 1683
            IMLSY+W     V ++Y  L  + F+ W+D +   +        A A++NS  +V F+++ Y+ S NC  E +YA  K+KP+I
Sbjct:  413 IMLSYNWGIQSFVREVYMELSQQTFQTWMDIWGGMQGNINEAM-ATAVENSTMLVAFLTEKYQQSVNCNLELKYATMKEKPII 494          

BLAST of TIR domain-containing protein vs. Planmine SMEST
Match: SMESG000008937.1 (SMESG000008937.1)

HSP 1 Score: 1322.38 bits (3421), Expect = 0.000e+0
Identity = 676/691 (97.83%), Postives = 683/691 (98.84%), Query Frame = 1

Query:   25 MQATSKPQKRKVVGEEIVSKPITRKLTIDEINLKICSEAEDIINKVKSLQKFITDLQPQESSEFQQIVKAINSKYFSLNKFNVKLEDVKRLRLSNANVLIKLDIFNIYYTILVQILHNVFGKNYSEEIDNKFHSAIKNLIDIFFNYTDASSDFGKEFCKNDKLLHLYYKIISEFKENCLNKSLSKNITDLLRICISTLYNTMLHDVNENYTIIKEMKFLDLIKDLMKCEEGKIKRAALLFVAYIADETESKMFKSDLHSISYLIELLKKSLNTRFSRSQGLSTEELSKGIGKLSKNDENKQLLVEMGILPVLKMQLEKDDKRNQELALGVLWSLTFDEKNKILIQKEFRNKILELKTKLDKKCQAGLTHDTAGSQVPTLQTHSVESRAKSCNRIPKVIGNLESKKDMNSVSYDDFLCFETQFDENTEEISKNSFNYKNILDGLTWTLTNLEEVKSKKQETEEEEVATKDHIMLSYSWSNADIVMKIYDCLVNKGFKLWIDKYXXXXXXXXXXXXAQAIQNSYAVVIFISQNYKNSDNCRAEAQYAISKKKPVIPVMVQEKYRPDGWLGICIIGLQYCDFAGRYNFEDAXXXXXXXXXXXXAGNVQKKIDEIDHIDPVHVKNQSKNNQDITKWANERCKNWFDEIGIKRIVWPKHYTGNELDFLRTISQVPGEVFYQISKNELKITDLKDLR 2097
            MQATSKPQK+KVVGEEIVSKPITRKLTIDEINLKICS AEDIINKVKSLQKFITDLQPQESSEFQQIVKAINSKYFSLNKFNVKLEDVKRLRLSNANVLIKLDIFNIYYTILVQILHNVFGKNYSEEIDNKFHSAIKNLIDIFFNYTDA+SDFGKEFCKNDKLLHLYYKIISEFKENCLNKSLSKN+TDLLRICISTLYNTMLHDVNENYTIIKEMKFLDLIKDLMKCEEGKIKRAALLFVAYIA ETESKMFKSDLHSISYLIELLKKSLNTRFSRSQGLSTEELSKGIGKLSKNDENKQLLVEMGILPVLKMQLEKDDKRNQELALGVLWSLTFDEKNKILIQKEFRNKILELKTKLDKKCQAGLTHD  GSQVPTLQTHSVES A +CNRIP++IGNLESKKDMNSVSYDD LCFETQFDENTEEISKNSFNYKNILDGLTWTLTNLEEVKSKKQETEEEEVATKDHIMLSYSWSNADIVMKIYDCLVNKGFKLWIDKYNMSEEENLMESMAQAIQNSYAVVIFISQNYKNSDNCRAEAQYAISKKKPVIPVMVQEKYRPDGWLGICIIGLQYCDFAGRYNFEDALILLLKQIKRIKAGNVQKKIDEIDHIDPVHVKNQSKNNQDITKWANERCKNWFDEIGIK IVWPKHYTGNELDFLRTISQVPGEVFYQI+KNELKITDLKDLR
Sbjct:    1 MQATSKPQKQKVVGEEIVSKPITRKLTIDEINLKICSVAEDIINKVKSLQKFITDLQPQESSEFQQIVKAINSKYFSLNKFNVKLEDVKRLRLSNANVLIKLDIFNIYYTILVQILHNVFGKNYSEEIDNKFHSAIKNLIDIFFNYTDANSDFGKEFCKNDKLLHLYYKIISEFKENCLNKSLSKNLTDLLRICISTLYNTMLHDVNENYTIIKEMKFLDLIKDLMKCEEGKIKRAALLFVAYIAGETESKMFKSDLHSISYLIELLKKSLNTRFSRSQGLSTEELSKGIGKLSKNDENKQLLVEMGILPVLKMQLEKDDKRNQELALGVLWSLTFDEKNKILIQKEFRNKILELKTKLDKKCQAGLTHDITGSQVPTLQTHSVESPAINCNRIPEIIGNLESKKDMNSVSYDDVLCFETQFDENTEEISKNSFNYKNILDGLTWTLTNLEEVKSKKQETEEEEVATKDHIMLSYSWSNADIVMKIYDCLVNKGFKLWIDKYNMSEEENLMESMAQAIQNSYAVVIFISQNYKNSDNCRAEAQYAISKKKPVIPVMVQEKYRPDGWLGICIIGLQYCDFAGRYNFEDALILLLKQIKRIKAGNVQKKIDEIDHIDPVHVKNQSKNNQDITKWANERCKNWFDEIGIKSIVWPKHYTGNELDFLRTISQVPGEVFYQITKNELKITDLKDLR 691          

BLAST of TIR domain-containing protein vs. Planmine SMEST
Match: SMESG000008941.1 (SMESG000008941.1)

HSP 1 Score: 334.724 bits (857), Expect = 4.934e-104
Identity = 218/600 (36.33%), Postives = 350/600 (58.33%), Query Frame = 1

Query:  349 YTILVQILHNVFGKNYSEEIDNKFHSAIKNLIDIFFNYTDASSDFGKEFCKNDKLLHLYYKIISEFKENCLNKSLSKNITDLLRICISTLYNTMLHDVNENYTIIKEMKFLDLIKDLMKCEEGKIKRAALLFVAYIADETESKMFKSDLHSISYLIELLKKSLNT-RFSRSQGLSTEELSKGIGKLSKNDENKQLLVEMGILPVLKMQLEKDDKRNQELALGVLWSLTFDEKNKILIQKEFRNKILELKTKLDKKCQAGLTHDTAGSQVPTLQTHSVESRAKSCNRIPKVIGNLESKKDMNSVSYDDFLCFETQ---FDENTEEI---SKNSFNYKNILDGLTWTLTNL--EEVKSKKQE--TEEEEVATKDHIMLSYSWSNADIVMKIYDCLVNKGFKLWIDKYXXXXXXXXXXXXAQAIQNSYAVVIFISQNYKNSDNCRAEAQYAISKKKPVIPVMVQEKYRPDGWLGICIIGLQYCDFAGRYNFEDAXXXXXXXXXXXXAGNVQKKIDE------IDHIDPVHVKNQSKNNQDITKWANERCKNWFDEIGIKRIVWPKHYTGNELDFLRTISQVPGEVFYQISKNELKITDLKDLR 2097
            Y  L ++ + +   + S+E+ N    +   L+DIF   ++ + +FG E CK + L+  +  II E+K  C+N SLS+    +L + I  LY+T+++D   N   + ++K  + ++   KC    IK    L VAYI++E +S  F  D+ SI  +I++L  S+ T  +S  Q     EL K + +LSKND+NK+ +VEMGILP+LK  LE +  + + ++L +L++L++DE+NK  I ++F   + +L+          L       Q+P      + +  K  N + K   N   K ++ +  Y      E++      N  +I    ++S + K  L+GL   LTN   E + S   +  ++    + + H+M+SY   NAD  +K+YD L  + FKLWIDK++M   +NLME+MAQA++NS+AV+I IS  YKNS++CRAEAQYA   KKP+IP+++QEKYRPDGWLGICI G+QY +F+G+Y+ E+++ +L+KQ+++ K  N Q+K +        DH +         N   ++ W+N +  NWF +IGIK+  W  HYTG+EL+FL++IS   GE   +  ++EL+I DLKD+R
Sbjct:   82 YLSLTKLFNEIKENHTSKEVGNNLPRSFTVLLDIFARCSETNQEFGDEICKRENLIQFFVMIIKEYKLPCINGSLSETELKILELSIRNLYSTLIYDSEVNIHKLHKLKVWESLQYFEKCPNQDIKIRLALLVAYISEEKDSSGFVVDISSIPIIIKVLSDSVKTAEYSSKQEYPILELIKAVERLSKNDKNKRKMVEMGILPILKTLLETNFTKYRHISLSILFNLSYDERNKSEIAEKFLQILFDLQ---------HLKTLKPKEQLP------ISTMNKPDNHLDKNALNQNIKGEIGTTFYIQPPAKESERALSQSNNPQIYGSQQDSASQK--LNGLMSILTNYQKENIPSPPSDNNSQTNPSSNQKHVMISYCHENADFALKLYDELKARNFKLWIDKHDMRANQNLMEAMAQAVENSWAVIICISHCYKNSESCRAEAQYAKDNKKPLIPIIIQEKYRPDGWLGICITGIQYLNFSGKYSSEESMGMLVKQLEQFK--NEQQKSEPTKPQIITDHSNLEQSNENQSNGIKLSDWSNSKVINWFRQIGIKKFAWKSHYTGSELEFLKSIS---GEKLLEFCQSELEIYDLKDIR 659          

BLAST of TIR domain-containing protein vs. Planmine SMEST
Match: SMESG000008947.1 (SMESG000008947.1)

HSP 1 Score: 270.396 bits (690), Expect = 2.414e-79
Identity = 181/508 (35.63%), Postives = 289/508 (56.89%), Query Frame = 1

Query:  592 LLRICISTLYNTMLHDVNENYTIIKEMKFLDLIKDLMKCEEGKIKRAALLFVAYIADETESKM---FKSDLHSISYLIELLKKSLNTRFSRSQGLSTEELSKGIGKLSKNDENKQLLVEMGILPVLKMQLEKDDKRNQELALGVLWSLTFDEKNKILIQKEFRNKILELKTKLDKKCQAGLTHDTAGSQVPTLQTHSVESRAKSCNRIPKVIGNLESKKDMNSVSYDDFLCFETQFDENTEEISKNSFNYKNILDGLTWTLTNLEEVKSKKQETEEE-EVATKD-HIMLSYSWSNADIVMKIYDCLVNKGFKLWIDKYXXXXXXXXXXXXAQAIQNSYAVVIFISQNYKNSDNCRAEAQYAISKKKPVIPVMVQEKYRPDGWLGICIIGLQYCDFAGRYNFEDAXXXXXXXXXXXXAGNVQKKIDEIDHI-DPVHVKNQSKNNQDITKWANERCKNWFDEIGIKRIVWPKHYTGNELDFLRTISQVPGEVFYQISKNELKITDLKDLR 2097
            +L   I+  Y   ++   E   ++  MKF++LI+D +     +IK  +LL +A+++ E+  K+    +     +SYL +LL K +     +++  S  EL++GI KLSK DENK++LV+ GILPVL + ++    R ++++L +LW+L F++KN+ +I   F + I + +                                   +R P + G L +K D      D  L   T+    TE++ + +  Y N+LDGL W L +       +   E+  E++ ++ H M+SYS SNA IVM IY  L  +GFK+WIDKYN++++EN+ME+MAQA++NS AV+IF+S  YKNS+ CR+EAQYA    KP+IPV+V+++Y PDGWLG+CI GLQY DF  +  F+ ++ LL  QI  IK     K  ++ D   +P    N S NN     W +E  K W  +IG+++I W  +Y G ++ FL+++S+   E F  I + + K++DLK++R
Sbjct:  262 ILNDTITIPYTISINGNPEQIAVLHSMKFVELIQDFLLSPYERIKLNSLLLIAHLSSESHFKLEIIQEKRPEYLSYLTQLLNKYMTDYHGQTRAYSILELARGIEKLSKVDENKRILVKCGILPVLMLLIKNKSMRYKKISLSILWNLAFNKKNRQVINSMFSDIISDFRR----------------------------------DRFPLLYGTL-TKNDKRKTQNDLELRNVTENLNETEKMPRKT--YINVLDGLKWILQDHRNNSKTRDACEDSNEISERETHFMISYSHSNAKIVMDIYQILQKQGFKVWIDKYNINDDENMMEAMAQAVENSIAVIIFLSTKYKNSEYCRSEAQYAFKLNKPLIPVVVEKEYHPDGWLGLCISGLQYFDFTSKTPFKKSMALLTDQISTIKNRRFSKIFEKSDFPKEPSVPSNPSPNN-----WTHEEVKTWLKKIGVRKIKWKANYAGQDIMFLKSLSK---EKFLDICRIDFKMSDLKEMR 724          

BLAST of TIR domain-containing protein vs. Planmine SMEST
Match: SMESG000008947.1 (SMESG000008947.1)

HSP 1 Score: 270.396 bits (690), Expect = 3.777e-79
Identity = 181/508 (35.63%), Postives = 289/508 (56.89%), Query Frame = 1

Query:  592 LLRICISTLYNTMLHDVNENYTIIKEMKFLDLIKDLMKCEEGKIKRAALLFVAYIADETESKM---FKSDLHSISYLIELLKKSLNTRFSRSQGLSTEELSKGIGKLSKNDENKQLLVEMGILPVLKMQLEKDDKRNQELALGVLWSLTFDEKNKILIQKEFRNKILELKTKLDKKCQAGLTHDTAGSQVPTLQTHSVESRAKSCNRIPKVIGNLESKKDMNSVSYDDFLCFETQFDENTEEISKNSFNYKNILDGLTWTLTNLEEVKSKKQETEEE-EVATKD-HIMLSYSWSNADIVMKIYDCLVNKGFKLWIDKYXXXXXXXXXXXXAQAIQNSYAVVIFISQNYKNSDNCRAEAQYAISKKKPVIPVMVQEKYRPDGWLGICIIGLQYCDFAGRYNFEDAXXXXXXXXXXXXAGNVQKKIDEIDHI-DPVHVKNQSKNNQDITKWANERCKNWFDEIGIKRIVWPKHYTGNELDFLRTISQVPGEVFYQISKNELKITDLKDLR 2097
            +L   I+  Y   ++   E   ++  MKF++LI+D +     +IK  +LL +A+++ E+  K+    +     +SYL +LL K +     +++  S  EL++GI KLSK DENK++LV+ GILPVL + ++    R ++++L +LW+L F++KN+ +I   F + I + +                                   +R P + G L +K D      D  L   T+    TE++ + +  Y N+LDGL W L +       +   E+  E++ ++ H M+SYS SNA IVM IY  L  +GFK+WIDKYN++++EN+ME+MAQA++NS AV+IF+S  YKNS+ CR+EAQYA    KP+IPV+V+++Y PDGWLG+CI GLQY DF  +  F+ ++ LL  QI  IK     K  ++ D   +P    N S NN     W +E  K W  +IG+++I W  +Y G ++ FL+++S+   E F  I + + K++DLK++R
Sbjct:  282 ILNDTITIPYTISINGNPEQIAVLHSMKFVELIQDFLLSPYERIKLNSLLLIAHLSSESHFKLEIIQEKRPEYLSYLTQLLNKYMTDYHGQTRAYSILELARGIEKLSKVDENKRILVKCGILPVLMLLIKNKSMRYKKISLSILWNLAFNKKNRQVINSMFSDIISDFRR----------------------------------DRFPLLYGTL-TKNDKRKTQNDLELRNVTENLNETEKMPRKT--YINVLDGLKWILQDHRNNSKTRDACEDSNEISERETHFMISYSHSNAKIVMDIYQILQKQGFKVWIDKYNINDDENMMEAMAQAVENSIAVIIFLSTKYKNSEYCRSEAQYAFKLNKPLIPVVVEKEYHPDGWLGLCISGLQYFDFTSKTPFKKSMALLTDQISTIKNRRFSKIFEKSDFPKEPSVPSNPSPNN-----WTHEEVKTWLKKIGVRKIKWKANYAGQDIMFLKSLSK---EKFLDICRIDFKMSDLKEMR 744          

BLAST of TIR domain-containing protein vs. Planmine SMEST
Match: SMESG000035587.1 (SMESG000035587.1)

HSP 1 Score: 110.538 bits (275), Expect = 7.078e-25
Identity = 131/516 (25.39%), Postives = 220/516 (42.64%), Query Frame = 1

Query:  607 ISTLYNTMLHDVNENYTIIKEMK--FLDLIKDLMKCEE--GKIKRAALLFVAYIADETESKMFKSDLHSISYLIELLKKSLNTRFSRSQGLSTEELSKGIGKLSKNDENKQLL-VEMGILPVLKMQLEKDDKRNQELALGVLWSLTFDEKNKILIQKEFRNKILELKTKLDKKCQAGLTHDTAGSQVPTLQTHSVESRAKSCNRIPKVIGNLESKKDMNSVSYDDFLCFETQFDENTEEISKNSFNYKNILDGLTWTLTNLEEVKSKKQETEEEEVATKDHIMLSYSWSNADIVMKIYDCLVNKGFKLWIDKYXXXXXXXXXXXXAQAIQNSYAVVIFISQNYKNSDNCRAEAQYAISKKKPVIPVMVQEKYRPDGWLGICIIGLQYCDFAGRYNFEDAXXXXXXXXXXXXAGNVQKKIDEID-HID-PVHV----------KNQSKNNQDIT------KWANERCKNWFDEIGIKRIVWPKHYTGNELDFLRTISQV---PGEVFYQISKNELKI 2076
            I+ ++N   H +++    + E+K  FL+++   + C++  G I   +L+ ++Y+ DE E  +F    + +  LI+ +K  +N    RS+G + +EL  G+ +LS NDE K ++  E GI  ++ +    +++   E  L V+  L F+                ++K KL       + H   G  +     HS    AK C                                                 +G+ W L N  +++S  +   E+     D  M SYSW+N D V++I   L +    +WID+       + +E+MA  I+NS  VVI  S  YKNS NCR EA+YA   KKP+IP++++ KY+P  WLGI      Y +F+ R N  +                VQ+ I  I  H++ PV +          KN+S +   I        W+ E   +W D+ GI  +   + + G +   +  +  +    G+ F    KNE K+
Sbjct:  157 ITIIHNFASHKLDKINYRVDEIKKTFLNIVN--LNCDDYYGLI---SLVTLSYLIDENEINLFDGHENIVKELIKKIK-LINENKLRSEGFTIKELIHGLRRLSANDEIKTIIDTENGIQVLIDILNSTNNENVIEPTLDVIKQLCFNN---------------DIKIKL-------INHYKIGETLTKFSNHS---NAKICQH----------------------------------------------YNGILWILDN--KLESLPKGNTEKTAIVFDAFM-SYSWANKDKVLEICSILKSYNVNVWIDQ--EEMISSTLEAMATGIENSKVVVIAASTAYKNSSNCRLEAEYAQKIKKPIIPLVMEHKYKPSNWLGILFGTKVYIEFSDRRNANEQ---------------VQQLIKNIKFHLNRPVKLAEKIDLNAGEKNRSNSRTRIVLVDEVKNWSCENVGDWLDKFGIGYL--KEKFIGVDGSMIEVMLDIRINSGDYFNNCLKNEFKM 573