Dicer-like protein 1
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30009440 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 2
Homology
BLAST of Dicer-like protein 1 vs. Ensembl Human
Match: DDX58 (DExD/H-box helicase 58 [Source:HGNC Symbol;Acc:HGNC:19102]) HSP 1 Score: 99.3673 bits (246), Expect = 9.804e-21 Identity = 143/563 (25.40%), Postives = 243/563 (43.16%), Query Frame = 2
Query: 905 LEPRKYQLEIYEKA-NGKDCVIFLPTGTGKTFIAAMLM---LKMLEENPFHRVAFLVDKVLLVMQQSKSFKGQFEDICLERFESQEKTVTRKLKLISLANEIIDSDHKCSIRDHDVIIATADFFKNILNKQQI-YWTDFSLVVLDEAHHCVKEHPYNKLLFEYHLYPQRVLLNKNELLSVXXXXXXXXXXXXXXXXWKIRRCKIIGLTASPS-GEL-DFDKTYELLKALLHSLGDVGIVTVTENIDELNEFTS-----LTNMESRI---VSYGESE-------------KDLRKL-MTTNFVFLLKKFERRVNGIGNGLILSSDTSLTIEEINNLKSQLSGLLVDVREIQKS----ILNHILALVDIIEAIDNIGYTIAKKKFDEILENENETVWYDNNIFNFKTISKEFQLLHQEQENSSI--INEIVKECKSLQDENRTILVLVEERRDAREYKNSLE-KEKLNFEFQLIVXXXXXXXXXXXXXMSVGEQKKALD-FIREKKSQIIIATSVVDEGIDLPQCDLVITVNPPTSVQALVQIRGRARKKDSRLLMLCRDQKTID 2482
+PR YQLE+ A GK+ +I PTG GKTF++ ++ LK + +V F +++ + QQ F FE + R + E + + + ++D+II T N L K I + F+L++ DE H+ K+HPYN ++F Y Q++ + L V IGLTAS G+ + D+ + + L SL I TV N++EL + +ESRI Y ++ KDL L N F +K+E+ + + ++ + + + L + ++K I++ + D ++ + + + FDEI ++ T ++ + +++S++ EN + + I++E L E TIL V+ R KN +E KL+F I+ G+G +++ GM++ QK LD F I+IATSV DEGID+ QC+LVI +V ++Q RGR R + S+ +L + I+
Sbjct: 38 FKPRNYQLELALPAMKGKNTIICAPTGCGKTFVSLLICEHHLKKFPQGQKGKVVFFANQIPVYEQQKSVFSKYFE-----------RHGYRVTGISGATAENVPVEQ--IVENNDIIILTPQILVNNLKKGTIPSLSIFTLMIFDECHNTSKQHPYNMIMFNY--LDQKLGGSSGPLPQV------------------------IGLTASVGVGDAKNTDEALDYICKLCASLDASVIATVKHNLEELEQVVYKPQKFFRKVESRISDKFKYIIAQLMRDTESLAKRICKDLENLSQIQNREFGTQKYEQWIVTVQKACMV-----FQMPDKDEESRICKALFLYTSHLRKYNDALIISEHARMKDALDYLKDFFSNVRAAGFDEI--EQDLTQRFEEKLQELESVSRD-----PSNENPKLEDLCFILQEEYHLNPETITIL-FVKTRALVDALKNWIEGNPKLSFLKPGIL--TGRGKTNQNTGMTLPAQKCILDAFKASGDHNILIATSVADEGIDIAQCNLVILYEYVGNVIKMIQTRGRGRARGSKCFLLTSNAGVIE 546
BLAST of Dicer-like protein 1 vs. Ensembl Human
Match: DDX58 (DExD/H-box helicase 58 [Source:HGNC Symbol;Acc:HGNC:19102]) HSP 1 Score: 98.9821 bits (245), Expect = 1.723e-20 Identity = 143/563 (25.40%), Postives = 243/563 (43.16%), Query Frame = 2
Query: 905 LEPRKYQLEIYEKA-NGKDCVIFLPTGTGKTFIAAMLM---LKMLEENPFHRVAFLVDKVLLVMQQSKSFKGQFEDICLERFESQEKTVTRKLKLISLANEIIDSDHKCSIRDHDVIIATADFFKNILNKQQI-YWTDFSLVVLDEAHHCVKEHPYNKLLFEYHLYPQRVLLNKNELLSVXXXXXXXXXXXXXXXXWKIRRCKIIGLTASPS-GEL-DFDKTYELLKALLHSLGDVGIVTVTENIDELNEFTS-----LTNMESRI---VSYGESE-------------KDLRKL-MTTNFVFLLKKFERRVNGIGNGLILSSDTSLTIEEINNLKSQLSGLLVDVREIQKS----ILNHILALVDIIEAIDNIGYTIAKKKFDEILENENETVWYDNNIFNFKTISKEFQLLHQEQENSSI--INEIVKECKSLQDENRTILVLVEERRDAREYKNSLE-KEKLNFEFQLIVXXXXXXXXXXXXXMSVGEQKKALD-FIREKKSQIIIATSVVDEGIDLPQCDLVITVNPPTSVQALVQIRGRARKKDSRLLMLCRDQKTID 2482
+PR YQLE+ A GK+ +I PTG GKTF++ ++ LK + +V F +++ + QQ F FE + R + E + + + ++D+II T N L K I + F+L++ DE H+ K+HPYN ++F Y Q++ + L V IGLTAS G+ + D+ + + L SL I TV N++EL + +ESRI Y ++ KDL L N F +K+E+ + + ++ + + + L + ++K I++ + D ++ + + + FDEI ++ T ++ + +++S++ EN + + I++E L E TIL V+ R KN +E KL+F I+ G+G +++ GM++ QK LD F I+IATSV DEGID+ QC+LVI +V ++Q RGR R + S+ +L + I+
Sbjct: 241 FKPRNYQLELALPAMKGKNTIICAPTGCGKTFVSLLICEHHLKKFPQGQKGKVVFFANQIPVYEQQKSVFSKYFE-----------RHGYRVTGISGATAENVPVEQ--IVENNDIIILTPQILVNNLKKGTIPSLSIFTLMIFDECHNTSKQHPYNMIMFNY--LDQKLGGSSGPLPQV------------------------IGLTASVGVGDAKNTDEALDYICKLCASLDASVIATVKHNLEELEQVVYKPQKFFRKVESRISDKFKYIIAQLMRDTESLAKRICKDLENLSQIQNREFGTQKYEQWIVTVQKACMV-----FQMPDKDEESRICKALFLYTSHLRKYNDALIISEHARMKDALDYLKDFFSNVRAAGFDEI--EQDLTQRFEEKLQELESVSRD-----PSNENPKLEDLCFILQEEYHLNPETITIL-FVKTRALVDALKNWIEGNPKLSFLKPGIL--TGRGKTNQNTGMTLPAQKCILDAFKASGDHNILIATSVADEGIDIAQCNLVILYEYVGNVIKMIQTRGRGRARGSKCFLLTSNAGVIE 749
BLAST of Dicer-like protein 1 vs. Ensembl Human
Match: IFIH1 (interferon induced with helicase C domain 1 [Source:HGNC Symbol;Acc:HGNC:18873]) HSP 1 Score: 76.2554 bits (186), Expect = 1.975e-13 Identity = 89/305 (29.18%), Postives = 142/305 (46.56%), Query Frame = 2
Query: 764 HRNNQDSHDKGKMHRDNLFKSKTEDIISQTVRKTELSDGLKNLKLLKLEPRKYQLEIYEKA-NGKDCVIFLPTGTGKTFIAAMLMLKMLEE----NPFHRVAFLVDKVLLVMQQSKSFKGQFEDICLERFESQEKTVTRKLKLISLANEIIDSDHKCS----IRDHDVIIATADFFKN-ILNKQQ-----IYWTDFSLVVLDEAHHCVKEHPYNKLLFEYHLYPQRVLLNKNELLSVXXXXXXXXXXXXXXXXWKIRRCKIIGLTASP--SGELDFDKTYELLKALLHSLGDVGIVTVTENIDEL 1627
H +N S D G M D S E++ ++ + EL + R YQ+E+ + A GK+ +I LPTG+GKT +A + L++ + +V LV+KVLLV Q F+ +F+ + + ++I L+ D+ K S ++ D+II+TA +N +LN + + +DFSL+++DE HH KE YN ++ Y + Q++ KN L + I +I+GLTASP G K E + L +L I TV EN+D+L
Sbjct: 276 HNSNMGS-DSGTMGSD----SDEENVAARASPEPEL------------QLRPYQMEVAQPALEGKNIIICLPTGSGKTRVAVYIAKDHLDKKKKASEPGKVIVLVNKVLLVEQL---FRKEFQPF-----------LKKWYRVIGLSG---DTQLKISFPEVVKSCDIIISTAQILENSLLNLENGEDAGVQLSDFSLIIIDECHHTNKEAVYNNIMRHYLM--QKL---KNNRLKKENKPV-------------IPLPQILGLTASPGVGGATKQAKAEEHILKLCANLDAFTIKTVKENLDQL 528 HSP 2 Score: 55.0694 bits (131), Expect = 6.199e-7 Identity = 29/80 (36.25%), Postives = 48/80 (60.00%), Query Frame = 2
Query: 2255 MSVGEQKKALDFIREKKSQIIIATSVVDEGIDLPQCDLVITVNPPTSVQALVQIRGRARKKDSRLLMLCRDQKTIDILHE 2494
M+ EQK+ + R K ++IAT+V +EG+D+ +C++VI T+ A+VQ RGRAR +S +++ + I HE
Sbjct: 766 MTQNEQKEVISKFRTGKINLLIATTVAEEGLDIKECNIVIRYGLVTNEIAMVQARGRARADESTYVLVAHSGSGV-IEHE 844
BLAST of Dicer-like protein 1 vs. Ensembl Human
Match: DHX58 (DExH-box helicase 58 [Source:HGNC Symbol;Acc:HGNC:29517]) HSP 1 Score: 68.1662 bits (165), Expect = 1.106e-12 Identity = 53/164 (32.32%), Postives = 83/164 (50.61%), Query Frame = 2
Query: 905 LEPRKYQLEIYEKA-NGKDCVIFLPTGTGKTFIAAMLMLKMLEENPFHRVAFLVDKVLLVMQQSKSFKGQFEDICLERFESQEKTVTRKLKLISLANEI-IDSDHKCSIRDHDVIIATADFFKNILN----KQQIYWTDFSLVVLDEAHHCVKEHPYNKLLFEY 1378
+E R YQ E+ A GK+ +I+LPTG GKT AA + + LE +V LV++V LV Q + F+ R TVT +L+ ++ + R HD++I TA+ + L ++ + T FSL+V+DE HH K+ YN ++ +Y
Sbjct: 1 MELRSYQWEVIMPALEGKNIIIWLPTGAGKTRAAAYVAKRHLETVDGAKVVVLVNRVHLVTQHGEEFR---------RMLDGRWTVT------TLSGDMGPRAGFGHLARCHDLLICTAELLQMALTSPEEEEHVELTVFSLIVVDECHHTHKDTVYNVIMSQY 149
BLAST of Dicer-like protein 1 vs. Ensembl Human
Match: DHX58 (DExH-box helicase 58 [Source:HGNC Symbol;Acc:HGNC:29517]) HSP 1 Score: 70.4774 bits (171), Expect = 2.357e-12 Identity = 53/164 (32.32%), Postives = 83/164 (50.61%), Query Frame = 2
Query: 905 LEPRKYQLEIYEKA-NGKDCVIFLPTGTGKTFIAAMLMLKMLEENPFHRVAFLVDKVLLVMQQSKSFKGQFEDICLERFESQEKTVTRKLKLISLANEI-IDSDHKCSIRDHDVIIATADFFKNILN----KQQIYWTDFSLVVLDEAHHCVKEHPYNKLLFEY 1378
+E R YQ E+ A GK+ +I+LPTG GKT AA + + LE +V LV++V LV Q + F+ R TVT +L+ ++ + R HD++I TA+ + L ++ + T FSL+V+DE HH K+ YN ++ +Y
Sbjct: 1 MELRSYQWEVIMPALEGKNIIIWLPTGAGKTRAAAYVAKRHLETVDGAKVVVLVNRVHLVTQHGEEFR---------RMLDGRWTVT------TLSGDMGPRAGFGHLARCHDLLICTAELLQMALTSPEEEEHVELTVFSLIVVDECHHTHKDTVYNVIMSQY 149
BLAST of Dicer-like protein 1 vs. Ensembl Celegans
Match: drh-3 (Dicer Related Helicase [Source:UniProtKB/TrEMBL;Acc:Q93413]) HSP 1 Score: 119.783 bits (299), Expect = 2.960e-27 Identity = 148/568 (26.06%), Postives = 252/568 (44.37%), Query Frame = 2
Query: 914 RKYQLEIYEKA-NGKDCVIFLPTGTGKTFIAAMLMLKMLEENPFH----RVAFLVDKVLLVMQQSKSF----KGQFEDICLERFESQEKTVTRKLKLISLANEIIDSDHKCSIRDHDVIIATADFFKNILNKQQIYWTDFSLVVLDEAHHCVKEHPYNKLLFEYHLYPQRVLLNKNELLSVXXXXXXXXXXXXXXXXWKIRRCKIIGLTASPSGELDFDK--------TYELLKALLHSLGDVGIVTVTENIDELNEFTSLTNMESRIVSYGESEKDLRKLMTTNFVFLLKKFERRVNGIGNGLILSSDTSLTIEEINNLK-----------SQLSGLLVDVREIQ-------------KSILNHILALVDIIEAIDNIGYTIAKKKFDEILENENETVWYDNNIFNFKTISKEFQLLHQEQENSSIINEIVKECKS-------LQDENRTILVLVEERRDAREYKNSLEKEKLNFEF----QLIVXXXXXXXXXXXXXMSVGEQKKALDFIREKKSQIIIATSVVDEGIDLPQCDLVITVN-PPTSVQALVQIRGRARKKDSRLLML 2458
R YQ E+ + A GK+CVI PTG+GKT +A LK +EE RV LV K+ LV QQ F G +E + F E +V+ + +E+I + S+ ++I + +++ +++Y +DFS+++ DE H K HPY VL+N+ ++EWK + +IIGLTAS S ++D K Y +L AL+++ + +T +IDELNE + +S + E LR + KF + + + ++ IN K S L G++ ++ ++ + +VD++ A+ + + +K ++ E+ +ETV Y I + T+ + Q S+ EIV K+ + E+R +++ V +R A+ + L + K+ +F + +VG+ K + EQ+ LD + ++I+ATSVV+EG+D+ C+L+I N S LVQ RGRAR K+SR ++L
Sbjct: 372 RTYQEELVQPALEGKNCVIVAPTGSGKTEVAIYAALKHIEERTSQGKPSRVVLLVPKIPLVGQQKDRFLKYCNGMYE---VNGFHGSESSVSGTGR----RDEVIAT--HVSVMTPQILI---NMLQSVRQNERLYVSDFSMMIFDEVHKAAKNHPY-------------VLINQ------------------MVQEWKYEKPQIIGLTASLSVKVDGQKDENQMLNDIYNML-ALINA-PHLSTITRQSSIDELNEHVGKPD-DSVELCLPAKENILRDYIERYLNHAHGKFLEELASMSKS--TGRNNTIPPNMINTFKKNQPKNYEYYDSLLQGIIQELNKLNVPEKWNSQTWAKYMKVYLEARGIVDLMPAM--VAFKYMEKAIGKLNESHSETVEYSTFIKDHDTLKQTIQ---------SVEPEIVLRLKNTLTNQFHVAPESR-VIIFVTQRSTAQRVSDFLNESKVLDQFGNYGEQMVGYVLGTNKQGAVQQTSQEQQLTLDKFNNGRLKVIVATSVVEEGLDVTACNLIIKYNCSSGSAIQLVQQRGRARAKNSRSVLL 879
BLAST of Dicer-like protein 1 vs. Ensembl Celegans
Match: dcr-1 (Endoribonuclease dcr-1 Death-promoting deoxyribonuclease [Source:UniProtKB/Swiss-Prot;Acc:P34529]) HSP 1 Score: 68.1662 bits (165), Expect = 2.902e-11 Identity = 50/174 (28.74%), Postives = 83/174 (47.70%), Query Frame = 2
Query: 911 PRKYQLEIYEKANGKDCVIFLPTGTGKTFIAAMLM------LKMLEENPFHRVAFLVDKVLLVMQQS------KSFK-GQFEDICLERFESQEKTVTRKLKLISLANEIIDSDHKCS--IRDHDVIIATADFFKNILNKQQIYWTDFSLVVLDEAHHCV-KEHPYNKLLFEYHL 1384
PR YQ+E+ +KA K+ ++ L TG+GKTFIA +L+ L + R F+V+KV LV QQ+ SFK GQ ++ + DS +C ++ H V++ TA +++ + D +++ DE HH + +HPY ++ +Y L
Sbjct: 13 PRDYQVELLDKATKKNTIVQLGTGSGKTFIAVLLLKEYGVQLFAPLDQGGKRAFFVVEKVNLVEQQAIHIEVHTSFKVGQVHG--------------------QTSSGLWDSKEQCDQFMKRHHVVVITAQCLLDLIRHAYLKIEDMCVLIFDECHHALGSQHPYRSIMVDYKL 166 HSP 2 Score: 53.5286 bits (127), Expect = 8.175e-7 Identity = 23/54 (42.59%), Postives = 39/54 (72.22%), Query Frame = 2
Query: 2315 IIATSVVDEGIDLPQCDLVITVNPPTSVQALVQIRGRARKKDSRLLMLCRDQKT 2476
+IATSV++EG+D+ QC+LVI + P +++ VQ +GRAR+ SR ++ ++ T
Sbjct: 457 LIATSVLEEGVDVKQCNLVIKFDRPLDMRSYVQSKGRARRAGSRYVITVEEKDT 510
BLAST of Dicer-like protein 1 vs. Ensembl Celegans
Match: dcr-1 (Endoribonuclease dcr-1 Death-promoting deoxyribonuclease [Source:UniProtKB/Swiss-Prot;Acc:P34529]) HSP 1 Score: 68.1662 bits (165), Expect = 2.902e-11 Identity = 50/174 (28.74%), Postives = 83/174 (47.70%), Query Frame = 2
Query: 911 PRKYQLEIYEKANGKDCVIFLPTGTGKTFIAAMLM------LKMLEENPFHRVAFLVDKVLLVMQQS------KSFK-GQFEDICLERFESQEKTVTRKLKLISLANEIIDSDHKCS--IRDHDVIIATADFFKNILNKQQIYWTDFSLVVLDEAHHCV-KEHPYNKLLFEYHL 1384
PR YQ+E+ +KA K+ ++ L TG+GKTFIA +L+ L + R F+V+KV LV QQ+ SFK GQ ++ + DS +C ++ H V++ TA +++ + D +++ DE HH + +HPY ++ +Y L
Sbjct: 13 PRDYQVELLDKATKKNTIVQLGTGSGKTFIAVLLLKEYGVQLFAPLDQGGKRAFFVVEKVNLVEQQAIHIEVHTSFKVGQVHG--------------------QTSSGLWDSKEQCDQFMKRHHVVVITAQCLLDLIRHAYLKIEDMCVLIFDECHHALGSQHPYRSIMVDYKL 166 HSP 2 Score: 53.5286 bits (127), Expect = 8.175e-7 Identity = 23/54 (42.59%), Postives = 39/54 (72.22%), Query Frame = 2
Query: 2315 IIATSVVDEGIDLPQCDLVITVNPPTSVQALVQIRGRARKKDSRLLMLCRDQKT 2476
+IATSV++EG+D+ QC+LVI + P +++ VQ +GRAR+ SR ++ ++ T
Sbjct: 457 LIATSVLEEGVDVKQCNLVIKFDRPLDMRSYVQSKGRARRAGSRYVITVEEKDT 510
BLAST of Dicer-like protein 1 vs. Ensembl Celegans
Match: drh-1 (Dicer Related Helicase [Source:UniProtKB/TrEMBL;Acc:V6CIX1]) HSP 1 Score: 63.5438 bits (153), Expect = 5.019e-10 Identity = 43/173 (24.86%), Postives = 78/173 (45.09%), Query Frame = 2
Query: 914 RKYQLEIYEKA-NGKDCVIFLPTGTGKTFIAAMLMLKMLE----ENPFHRVAFLVDKVLLVMQQSKSFKGQFEDIC-LERFESQEKTVTRKLKLISLANEIIDSDHKCSIRDHDVIIATADFFKNILNKQ-----------QIYWTDFSLVVLDEAHHCVKEHPYNKLLFEYH 1381
R YQ E+ + A GK+ ++ PTG+GKT IAA ++ + E E + F+ +++ QQ+ S + + + + + TR + I+ D+I+AT N+ N+ Q + + F+++ DE H+ VK PY+ ++ EYH
Sbjct: 36 RNYQEELCQVALQGKNTIVTAPTGSGKTVIAANIIKEHFESRSSEGKRFKALFMTPNSMILNQQAASISSYLDHVYHTQIIQGSDNVPTRNV-----------------IQSKDLIVATPQMIVNLCNEHRNSLDDESRLDQFFLSTFTIIFFDECHNTVKNSPYSNIMREYH 191 HSP 2 Score: 50.447 bits (119), Expect = 6.083e-6 Identity = 27/75 (36.00%), Postives = 46/75 (61.33%), Query Frame = 2
Query: 2267 EQKKALDFIREKKSQIIIATSVVDEGIDLPQCDLVITVNPPTSVQALVQIRGRARKKDSRLLMLC-----RDQKT 2476
+Q + L + + +I+++TSV +EG+D+P+C LVI N T+ A VQ RGR R +S +++ RDQ++
Sbjct: 496 KQMEKLKMFADGEIRILVSTSVAEEGLDVPECSLVIKYNYATNEIAHVQRRGRGRALNSECVLITNSIALRDQES 570
BLAST of Dicer-like protein 1 vs. Ensembl Celegans
Match: drh-1 (Dicer Related Helicase [Source:UniProtKB/TrEMBL;Acc:V6CIX1]) HSP 1 Score: 62.3882 bits (150), Expect = 1.211e-9 Identity = 43/173 (24.86%), Postives = 78/173 (45.09%), Query Frame = 2
Query: 914 RKYQLEIYEKA-NGKDCVIFLPTGTGKTFIAAMLMLKMLE----ENPFHRVAFLVDKVLLVMQQSKSFKGQFEDIC-LERFESQEKTVTRKLKLISLANEIIDSDHKCSIRDHDVIIATADFFKNILNKQ-----------QIYWTDFSLVVLDEAHHCVKEHPYNKLLFEYH 1381
R YQ E+ + A GK+ ++ PTG+GKT IAA ++ + E E + F+ +++ QQ+ S + + + + + TR + I+ D+I+AT N+ N+ Q + + F+++ DE H+ VK PY+ ++ EYH
Sbjct: 294 RNYQEELCQVALQGKNTIVTAPTGSGKTVIAANIIKEHFESRSSEGKRFKALFMTPNSMILNQQAASISSYLDHVYHTQIIQGSDNVPTRNV-----------------IQSKDLIVATPQMIVNLCNEHRNSLDDESRLDQFFLSTFTIIFFDECHNTVKNSPYSNIMREYH 449 HSP 2 Score: 50.447 bits (119), Expect = 5.942e-6 Identity = 27/75 (36.00%), Postives = 46/75 (61.33%), Query Frame = 2
Query: 2267 EQKKALDFIREKKSQIIIATSVVDEGIDLPQCDLVITVNPPTSVQALVQIRGRARKKDSRLLMLC-----RDQKT 2476
+Q + L + + +I+++TSV +EG+D+P+C LVI N T+ A VQ RGR R +S +++ RDQ++
Sbjct: 754 KQMEKLKMFADGEIRILVSTSVAEEGLDVPECSLVIKYNYATNEIAHVQRRGRGRALNSECVLITNSIALRDQES 828
BLAST of Dicer-like protein 1 vs. Ensembl Fly
Match: Dcr-2 (gene:FBgn0034246 transcript:FBtr0086904) HSP 1 Score: 62.7734 bits (151), Expect = 1.523e-9 Identity = 42/169 (24.85%), Postives = 83/169 (49.11%), Query Frame = 2
Query: 899 LKLEPRKYQLEIYEKANGKDCVIFLPTGTGKTFIAAMLMLKMLE------ENPFHRVAFLVDKVLLVMQQSKSFKGQFEDICLE---RFESQEKTV---TRKLKLISLANEIIDSDHKCSIRDHDVIIATADFFKNILNKQQIYWTDFSLVVLDEAHHCVKEHPYNKLL 1369
++++PR YQL + + + +++LPTG+GKTF+A +++ + + E+ R F+ + V L QQ+ + + C F E+ V TR + SD I+ + V++ TA F +++ + + + S+V++DE HH HP+ + +
Sbjct: 4 VEIKPRGYQLRLVDHLTKSNGIVYLPTGSGKTFVAILVLKRFSQDFDKPIESGGKRALFMCNTVELARQQAMAVRR-----CTNFKVGFYVGEQGVDDWTRGMW----------SD---EIKKNQVLVGTAQVFLDMVTQTYVALSSLSVVIIDECHHGTGHHPFREFM 154 HSP 2 Score: 50.8322 bits (120), Expect = 6.887e-6 Identity = 24/78 (30.77%), Postives = 47/78 (60.26%), Query Frame = 2
Query: 2270 QKKALDFIREKKSQIIIATSVVDEGIDLPQCDLVITVNPPTSVQALVQIRGRARKKDSRLLMLCRD---QKTIDILHE 2494
QK A+ R+ + ++I +SV++EGID+ C+ V ++P + VQ +GRAR +++ ++ D +KTI +++
Sbjct: 443 QKSAIQQFRDGNANLMICSSVLEEGIDVQACNHVFILDPVKTFNMYVQSKGRARTTEAKFVLFTADKEREKTIQQIYQ 520
BLAST of Dicer-like protein 1 vs. Ensembl Fly
Match: Dcr-2 (gene:FBgn0034246 transcript:FBtr0340217) HSP 1 Score: 62.7734 bits (151), Expect = 1.576e-9 Identity = 42/169 (24.85%), Postives = 83/169 (49.11%), Query Frame = 2
Query: 899 LKLEPRKYQLEIYEKANGKDCVIFLPTGTGKTFIAAMLMLKMLE------ENPFHRVAFLVDKVLLVMQQSKSFKGQFEDICLE---RFESQEKTV---TRKLKLISLANEIIDSDHKCSIRDHDVIIATADFFKNILNKQQIYWTDFSLVVLDEAHHCVKEHPYNKLL 1369
++++PR YQL + + + +++LPTG+GKTF+A +++ + + E+ R F+ + V L QQ+ + + C F E+ V TR + SD I+ + V++ TA F +++ + + + S+V++DE HH HP+ + +
Sbjct: 4 VEIKPRGYQLRLVDHLTKSNGIVYLPTGSGKTFVAILVLKRFSQDFDKPIESGGKRALFMCNTVELARQQAMAVRR-----CTNFKVGFYVGEQGVDDWTRGMW----------SD---EIKKNQVLVGTAQVFLDMVTQTYVALSSLSVVIIDECHHGTGHHPFREFM 154 HSP 2 Score: 50.8322 bits (120), Expect = 6.886e-6 Identity = 24/78 (30.77%), Postives = 47/78 (60.26%), Query Frame = 2
Query: 2270 QKKALDFIREKKSQIIIATSVVDEGIDLPQCDLVITVNPPTSVQALVQIRGRARKKDSRLLMLCRD---QKTIDILHE 2494
QK A+ R+ + ++I +SV++EGID+ C+ V ++P + VQ +GRAR +++ ++ D +KTI +++
Sbjct: 443 QKSAIQQFRDGNANLMICSSVLEEGIDVQACNHVFILDPVKTFNMYVQSKGRARTTEAKFVLFTADKEREKTIQQIYQ 520
BLAST of Dicer-like protein 1 vs. Ensembl Fly
Match: Dcr-1 (gene:FBgn0039016 transcript:FBtr0084324) HSP 1 Score: 57.3806 bits (137), Expect = 7.220e-8 Identity = 24/54 (44.44%), Postives = 39/54 (72.22%), Query Frame = 2
Query: 2270 QKKALDFIREKKSQIIIATSVVDEGIDLPQCDLVITVNPPTSVQALVQIRGRAR 2431
Q++ L R ++I TSV++EGID+P+C+LV+ +PPT+ ++ VQ +GRAR
Sbjct: 551 QEEVLKRFRMHDCNVLIGTSVLEEGIDVPKCNLVVRWDPPTTYRSYVQCKGRAR 604
BLAST of Dicer-like protein 1 vs. Ensembl Zebrafish
Match: dhx58 (DEXH (Asp-Glu-X-His) box polypeptide 58 [Source:ZFIN;Acc:ZDB-GENE-120612-3]) HSP 1 Score: 107.071 bits (266), Expect = 1.265e-23 Identity = 140/536 (26.12%), Postives = 227/536 (42.35%), Query Frame = 2
Query: 899 LKLEPRKYQLEIYEKA-NGKDCVIFLPTGTGKTFIAAMLMLKMLEENPFHRVAFLVDKVLLVMQQSKSFKGQFEDICLERFESQEKTVTRKLKLISLANEIIDSDHKCS-IRDHDVIIATADFFKNILNK----QQIYWTDFSLVVLDEAHHCVKEHPYNKLLFEYHLYPQRVLLNKNELLSVXXXXXXXXXXXXXXXXWKIRRCKIIGLTASP--SGELDFDKTYELLKALLHSLGDVGIVTVTENIDELNEFTSLTNMESRIVSYGESEKD-----LRKLMTTNFVFLLKKFERRVNGIGNGLILSSDTSLTIE-EINNLKSQLSGLLVDVREIQKSILNHILALVDIIEAIDNIGYTIAKKKFDEILENENETVWYDNNIF---NFKTISKEFQLLHQEQ--ENSSIINEIVKECKSLQDENRTILVLVEERRDAREYKNSLEKEKLNFEFQL--IVXXXXXXXXXXXXXMSVGEQKKALDFIREKKSQIIIATSVVDEGIDLPQCDLVITVNPPTSVQALVQIRGRARKKDS 2443
++L R YQ E+ + A G++ +I+LPTG GKT A + K LE +VA LV+KV LV Q G + + K ++ +++ + + D +R D++I TA +N LN + + TDF+L+V+DE HH KE YNK+++ Y + + R +I+GLTASP G DK E + + +L D IV+ L F E IV +KD L+ +M F+ R + +G T E E + ++ + +G+ V+ R I + L H+ D + D I A + +E + + + +IF F S E + L + EN + + + QD N ++ + RR + + K N E Q I GA + M+ EQK + R+ ++I+TSV +EG+D+P+C+LV+ T+ A Q GRAR +S
Sbjct: 1 MELRLRPYQEEVVQAALRGENSIIWLPTGGGKTRAAVYVAEKHLETKANAKVAVLVNKVHLVDQHYMKEFGHY--------------LRHKYRIKAISGDSSEKDFFGRLVRVSDLVICTAQILENALNNMDEDKHVEITDFTLLVIDECHHTNKESVYNKIMWRY---------------------------VEKKVRKEGRLPQILGLTASPGTGGNKSLDKAVEHVLQICANL-DSKIVSTKNYTPMLQNFVPKPKKEYDIVE--RRDKDPFGDHLKSMMLMIHEFMPPTVSRGLRELG-----------TQEYEADVVELEKAGVKVNNRLIAQCAL-HLRKYNDALLINDTIRMVDAFRVLEEFYNSRSSKLLDGTDIFLQGLFDENSLELKHLASDARYENPKLAQLQSRLLEEFQDTNSRGIIFSKTRRGTHCLNDWV---KTNRELQRVNITAGILTGAGNGANNMTQTEQKSVISHFRQGYLNLLISTSVAEEGLDIPECNLVVRYGLLTNEIAQQQASGRARASNS 477
BLAST of Dicer-like protein 1 vs. Ensembl Zebrafish
Match: dhx58 (DEXH (Asp-Glu-X-His) box polypeptide 58 [Source:ZFIN;Acc:ZDB-GENE-120612-3]) HSP 1 Score: 107.071 bits (266), Expect = 2.023e-23 Identity = 136/533 (25.52%), Postives = 224/533 (42.03%), Query Frame = 2
Query: 899 LKLEPRKYQLEIYEKA-NGKDCVIFLPTGTGKTFIAAMLMLKMLEENPFHRVAFLVDKVLLVMQQSKSFKGQFEDICLERFESQEKTVTRKLKLISLANEIIDSDHKCS-IRDHDVIIATADFFKNILNK----QQIYWTDFSLVVLDEAHHCVKEHPYNKLLFEYHLYPQRVLLNKNELLSVXXXXXXXXXXXXXXXXWKIRRCKIIGLTASP--SGELDFDKTYELLKALLHSLGDVGIVTVTENIDELNEFTSLTNMESRIVSYGESEK---DLRKLMTTNFVFLLKKFERRVNGIGNGLILSSDTSLTIEEINNLKSQLSGLLVDVREIQKSILNHILALVDIIEAIDNIGYTIAKKKFDEILENENETVWYDNNIF---NFKTISKEFQLLHQEQ--ENSSIINEIVKECKSLQDENRTILVLVEERRDAREYKNSLEKEKLNFEFQL--IVXXXXXXXXXXXXXMSVGEQKKALDFIREKKSQIIIATSVVDEGIDLPQCDLVITVNPPTSVQALVQIRGRARKKDS 2443
++L R YQ E+ + A G++ +I+LPTG GKT A + K LE +VA LV+KV LV Q G + + K ++ +++ + + D +R D++I TA +N LN + + TDF+L+V+DE HH KE YNK+++ Y + + R +I+GLTASP G DK E + + +L D IV+ L F E IV + + L+ +M F+ R + +G E + ++ + +G+ V+ R I + L H+ D + D I A + +E + + + +IF F S E + L + EN + + + QD N ++ + RR + + K N E Q I GA + M+ EQK + R+ ++I+TSV +EG+D+P+C+LV+ T+ A Q GRAR +S
Sbjct: 1 MELRLRPYQEEVVQAALRGENSIIWLPTGGGKTRAAVYVAEKHLETKANAKVAVLVNKVHLVDQHYMKEFGHY--------------LRHKYRIKAISGDSSEKDFFGRLVRVSDLVICTAQILENALNNMDEDKHVEITDFTLLVIDECHHTNKESVYNKIMWRY---------------------------VEKKVRKEGRLPQILGLTASPGTGGNKSLDKAVEHVLQICANL-DSKIVSTKNYTPMLQNFVPKPKKEYDIVERRDKDPFGDHLKSMMLMIHEFMPPTVSRGLRELGTQEY----------EADVVELEKAGVKVNNRLIAQCAL-HLRKYNDALLINDTIRMVDAFRVLEEFYNSRSSKLLDGTDIFLQGLFDENSLELKHLASDARYENPKLAQLQSRLLEEFQDTNSRGIIFSKTRRGTHCLNDWV---KTNRELQRVNITAGILTGAGNGANNMTQTEQKSVISHFRQGYLNLLISTSVAEEGLDIPECNLVVRYGLLTNEIAQQQASGRARASNS 477
BLAST of Dicer-like protein 1 vs. Ensembl Zebrafish
Match: ifih1 (interferon induced with helicase C domain 1 [Source:ZFIN;Acc:ZDB-GENE-081104-438]) HSP 1 Score: 67.3958 bits (163), Expect = 5.670e-11 Identity = 67/215 (31.16%), Postives = 103/215 (47.91%), Query Frame = 2
Query: 914 RKYQLEIYEKA-NGKDCVIFLPTGTGKTFIAAMLMLKMLEE----NPFHRVAFLVDKVLLVMQQSKSFKGQFEDICLERFESQEKTVTRKLKLISLANEIIDSDHKCSIRDHDVIIATADFFKNILNKQQ------IYWTDFSLVVLDEAHHCVKEHPYNKLLFEYHLYPQRVLLNKNELLSVXXXXXXXXXXXXXXXXWKIRRCKIIGLTASPS 1525
R YQ+E+ A K+ ++ LPTG+GKT +A + + LE +V LV+KV LV Q +K +F RF + +V R +S A+++ S + I +D+II TA +N L K + I + F+L+V+DE HH K YN ++ Y Q+ N+N+LL D + +I+GLTASP
Sbjct: 298 RDYQMEVARPALEEKNIIVCLPTGSGKTRVAVFITKEHLERKQRMGQKGKVVVLVNKVPLVEQH---YKAEFG-----RFLKHQYSVER----VSGASQLKISFPQI-IEKNDIIICTAQILENSLAKAKNGDEDGIELSQFTLMVIDECHHTKKGGVYNHIMIRY--LKQK---NRNQLLKKQDKTL-------------VPIPQILGLTASPG 481
BLAST of Dicer-like protein 1 vs. Ensembl Zebrafish
Match: ifih1 (interferon induced with helicase C domain 1 [Source:ZFIN;Acc:ZDB-GENE-081104-438]) HSP 1 Score: 66.6254 bits (161), Expect = 1.211e-10 Identity = 67/215 (31.16%), Postives = 103/215 (47.91%), Query Frame = 2
Query: 914 RKYQLEIYEKA-NGKDCVIFLPTGTGKTFIAAMLMLKMLEE----NPFHRVAFLVDKVLLVMQQSKSFKGQFEDICLERFESQEKTVTRKLKLISLANEIIDSDHKCSIRDHDVIIATADFFKNILNKQQ------IYWTDFSLVVLDEAHHCVKEHPYNKLLFEYHLYPQRVLLNKNELLSVXXXXXXXXXXXXXXXXWKIRRCKIIGLTASPS 1525
R YQ+E+ A K+ ++ LPTG+GKT +A + + LE +V LV+KV LV Q +K +F RF + +V R +S A+++ S + I +D+II TA +N L K + I + F+L+V+DE HH K YN ++ Y Q+ N+N+LL D + +I+GLTASP
Sbjct: 298 RDYQMEVARPALEEKNIIVCLPTGSGKTRVAVFITKEHLERKQRMGQKGKVVVLVNKVPLVEQH---YKAEFG-----RFLKHQYSVER----VSGASQLKISFPQI-IEKNDIIICTAQILENSLAKAKNGDEDGIELSQFTLMVIDECHHTKKGGVYNHIMIRY--LKQK---NRNQLLKKQDKTL-------------VPIPQILGLTASPG 481 HSP 2 Score: 53.1434 bits (126), Expect = 1.691e-6 Identity = 25/69 (36.23%), Postives = 42/69 (60.87%), Query Frame = 2
Query: 2255 MSVGEQKKALDFIREKKSQIIIATSVVDEGIDLPQCDLVITVNPPTSVQALVQIRGRARKKDSRLLMLC 2461
M+ EQK L R + ++IAT+V +EG+D+ +C++VI T+ A++Q RGR R +DS ++
Sbjct: 729 MTAAEQKDVLKRFRTGEINLLIATTVAEEGLDIAECNVVIRYCLVTNEVAMIQARGRGRAEDSSYTLVA 797
BLAST of Dicer-like protein 1 vs. Ensembl Zebrafish
Match: ifih1 (interferon induced with helicase C domain 1 [Source:ZFIN;Acc:ZDB-GENE-081104-438]) HSP 1 Score: 65.855 bits (159), Expect = 1.534e-10 Identity = 68/215 (31.63%), Postives = 102/215 (47.44%), Query Frame = 2
Query: 914 RKYQLEIYEKA-NGKDCVIFLPTGTGKTFIAAMLMLKMLEE----NPFHRVAFLVDKVLLVMQQSKSFKGQFEDICLERFESQEKTVTRKLKLISLANEIIDSDHKCSIRDHDVIIATADFFKNILNKQQ------IYWTDFSLVVLDEAHHCVKEHPYNKLLFEYHLYPQRVLLNKNELLSVXXXXXXXXXXXXXXXXWKIRRCKIIGLTASPS 1525
R YQ+E+ A K+ ++ LPTG+GKT +A + + LE +V LV+KV LV Q K+ G RF + +V R +S A+++ S + I +D+II TA +N L K + I + F+L+V+DE HH K YN ++ Y Q+ N+N+LL D P +I+GLTASP
Sbjct: 5 RDYQMEVARPALEEKNIIVCLPTGSGKTRVAVFITKEHLERKQRMGQKGKVVVLVNKVPLVEQHYKAEFG--------RFLKHQYSVER----VSGASQLKISFPQI-IEKNDIIICTAQILENSLAKAKNGDEDGIELSQFTLMVIDECHHTKKGGVYNHIMIRY--LKQK---NRNQLLKKQDKTLVPIP-------------QILGLTASPG 188 HSP 2 Score: 53.1434 bits (126), Expect = 1.294e-6 Identity = 25/69 (36.23%), Postives = 42/69 (60.87%), Query Frame = 2
Query: 2255 MSVGEQKKALDFIREKKSQIIIATSVVDEGIDLPQCDLVITVNPPTSVQALVQIRGRARKKDSRLLMLC 2461
M+ EQK L R + ++IAT+V +EG+D+ +C++VI T+ A++Q RGR R +DS ++
Sbjct: 436 MTAAEQKDVLKRFRTGEINLLIATTVAEEGLDIAECNVVIRYCLVTNEVAMIQARGRGRAEDSSYTLVA 504
BLAST of Dicer-like protein 1 vs. Ensembl Xenopus
Match: gaa (glucosidase, alpha; acid [Source:Xenbase;Acc:XB-GENE-6054131]) HSP 1 Score: 117.087 bits (292), Expect = 2.150e-26 Identity = 148/572 (25.87%), Postives = 262/572 (45.80%), Query Frame = 2
Query: 905 LEPRKYQLEIYEKA-NGKDCVIFLPTGTGKTFIAAMLMLKMLEENPFHRVAFLVDKVLLVMQQ-SKSFKGQFEDICLERFESQEKTVTRKLKLISLANEIIDSDHKC----SIRDHDVIIATADFFKNILN----KQQIYWTDFSLVVLDEAHHCVKEHPYNKLLFEYHLYPQRVLLNKNELLSVXXXXXXXXXXXXXXXXWKIRRCKIIGLTASPSG--ELDFDKTYELLKALLHSLGDVGIVTVTENIDELNEFTSLTNMESRIVS------YGESEKDLRK-----LMTTNFV---FLLKKFERRVNGIGNGLILSSDTSLTIEEINNLKSQLSGLLVDVREIQKSILNHILALVDIIEAIDNIGYTIAKKKFDEILENENETVWYDNNIFNFKTISKEFQLLHQEQ-ENSSI--INEIVKECKSLQDENRTILVLVEERRDAREYKNSLEKEKLNFEFQLI----VXXXXXXXXXXXXXMSVGEQKKALDFIREKKSQIIIATSVVDEGIDLPQCDLVITVNPPTSVQALVQIRGRARKKDSRLLMLC-------RDQKTIDILHELM 2500
+E YQ E+ A GK+ +I+LPTG GKT A + ++ LE +VAF+V+KV LV Q S F+ +D K +++++ D++HKC +D+DVII TA +N L+ + + TDF+L+++DE HH K+ YNKL+ Y +R + K +L +I+GLTASP F K E + + +L I++ + ++L N + +V+ +G+ K+L K L T F F + +E++V + L + +I +K + + +R+ S+L H V + +A + + +KF I + + T + +F+ + + +L H + EN + + EI+K+ +R I + R+ N + + FQ + G G ++ K M+ EQ++ ++ R+ + ++++TSV +EG+D+PQC++V+ T+ A+VQ RGRAR +DS L R ++T +IL +LM
Sbjct: 1 MELHDYQWEVIAPALEGKNIIIWLPTGAGKTRAALYVAMRHLEMKRNAKVAFIVNKVHLVDQHFSNEFQPHLKD---------------KYTVVAISG---DTEHKCFFAQKTQDNDVIICTAQILQNALSSGSEEMHVELTDFTLLIIDECHHTHKDGVYNKLM---EGYLERKICRKGKL------------------------PQILGLTASPGTGRATSFHKAVEHILQICANLDTWRIMSAEVHREDLEAKAKQPNKQYDLVAQRTRDPFGDKLKELMKTIHGYLRTAEFSESEFGTQVYEQKVVELEK-----EAGQLAVLQIYWMKRTCA---LHLRKYNDSLLVH--DTVRMTDAYELLAEFYVTEKF--IRKQNDPTDTFLIQLFD-RNQATLLELAHDSRFENPKLTKLEEILKDQFQFSSVSRGI-IFTRTRQSTHSLHNWISGKDY---FQKMGIKTAPLTGAGYSNQSKHMTQNEQREVIEKFRKGQLNLLVSTSVAEEGLDIPQCNVVVRYGLMTNEIAMVQARGRARHEDSCYSFLAKSGGKEIRREQTNEILEDLM 510
BLAST of Dicer-like protein 1 vs. Ensembl Xenopus
Match: gaa (glucosidase, alpha; acid [Source:Xenbase;Acc:XB-GENE-6054131]) HSP 1 Score: 116.701 bits (291), Expect = 2.874e-26 Identity = 148/572 (25.87%), Postives = 264/572 (46.15%), Query Frame = 2
Query: 905 LEPRKYQLEIYEKA-NGKDCVIFLPTGTGKTFIAAMLMLKMLEENPFHRVAFLVDKVLLVMQQ-SKSFKGQFEDICLERFESQEKTVTRKLKLISLANEIIDSDHKC----SIRDHDVIIATADFFKNILN----KQQIYWTDFSLVVLDEAHHCVKEHPYNKLLFEYHLYPQRVLLNKNELLSVXXXXXXXXXXXXXXXXWKIRRCKIIGLTASPSG--ELDFDKTYELLKALLHSLGDVGIVTVTENIDELNEFTSLTNMESRIVS------YGESEKDLRK-----LMTTNFV---FLLKKFERRVNGIGNGLILSSDTSLTIEEINNLKSQLSGLLVDVREIQKSILNHILALVDIIEAIDNIGYTIAKKKFDEILENENETVWYDNNIFNFKTISKEFQLLHQEQ-ENSSI--INEIVKECKSLQDENRTILVLVEERRDAREYKNSLEKEKLNFEFQLI----VXXXXXXXXXXXXXMSVGEQKKALDFIREKKSQIIIATSVVDEGIDLPQCDLVITVNPPTSVQALVQIRGRARKKDSRLLMLC-------RDQKTIDILHELM 2500
+E YQ E+ A GK+ +I+LPTG GKT A + ++ LE +VAF+V+KV LV Q S F+ +D K +++++ D++HKC +D+DVII TA +N L+ + + TDF+L+++DE HH K+ YNKL+ Y +R + K +L +I+GLTASP F K E + + +L I++ + ++L N + +V+ +G+ K+L K L T F F + +E++V + L + ++ E + +K + + +R+ S+L H V + +A + + +KF I + + T + +F+ + + +L H + EN + + EI+K+ +R I + R+ N + + FQ + G G ++ K M+ EQ++ ++ R+ + ++++TSV +EG+D+PQC++V+ T+ A+VQ RGRAR +DS L R ++T +IL +LM
Sbjct: 1 MELHDYQWEVIAPALEGKNIIIWLPTGAGKTRAALYVAMRHLEMKRNAKVAFIVNKVHLVDQHFSNEFQPHLKD---------------KYTVVAISG---DTEHKCFFAQKTQDNDVIICTAQILQNALSSGSEEMHVELTDFTLLIIDECHHTHKDGVYNKLM---EGYLERKICRKGKLP------------------------QILGLTASPGTGRATSFHKAVEHILQICANLDTWRIMSAEVHREDLEAKAKQPNKQYDLVAQRTRDPFGDKLKELMKTIHGYLRTAEFSESEFGTQVYEQKV------VELEKEGAV---EADRMKRTCA---LHLRKYNDSLLVH--DTVRMTDAYELLAEFYVTEKF--IRKQNDPTDTFLIQLFD-RNQATLLELAHDSRFENPKLTKLEEILKDQFQFSSVSRGI-IFTRTRQSTHSLHNWISGKDY---FQKMGIKTAPLTGAGYSNQSKHMTQNEQREVIEKFRKGQLNLLVSTSVAEEGLDIPQCNVVVRYGLMTNEIAMVQARGRARHEDSCYSFLAKSGGKEIRREQTNEILEDLM 506
BLAST of Dicer-like protein 1 vs. Ensembl Xenopus
Match: gaa (glucosidase, alpha; acid [Source:Xenbase;Acc:XB-GENE-6054131]) HSP 1 Score: 116.316 bits (290), Expect = 3.363e-26 Identity = 148/572 (25.87%), Postives = 264/572 (46.15%), Query Frame = 2
Query: 905 LEPRKYQLEIYEKA-NGKDCVIFLPTGTGKTFIAAMLMLKMLEENPFHRVAFLVDKVLLVMQQ-SKSFKGQFEDICLERFESQEKTVTRKLKLISLANEIIDSDHKC----SIRDHDVIIATADFFKNILN----KQQIYWTDFSLVVLDEAHHCVKEHPYNKLLFEYHLYPQRVLLNKNELLSVXXXXXXXXXXXXXXXXWKIRRCKIIGLTASPSG--ELDFDKTYELLKALLHSLGDVGIVTVTENIDELNEFTSLTNMESRIVS------YGESEKDLRK-----LMTTNFV---FLLKKFERRVNGIGNGLILSSDTSLTIEEINNLKSQLSGLLVDVREIQKSILNHILALVDIIEAIDNIGYTIAKKKFDEILENENETVWYDNNIFNFKTISKEFQLLHQEQ-ENSSI--INEIVKECKSLQDENRTILVLVEERRDAREYKNSLEKEKLNFEFQLI----VXXXXXXXXXXXXXMSVGEQKKALDFIREKKSQIIIATSVVDEGIDLPQCDLVITVNPPTSVQALVQIRGRARKKDSRLLMLC-------RDQKTIDILHELM 2500
+E YQ E+ A GK+ +I+LPTG GKT A + ++ LE +VAF+V+KV LV Q S F+ +D K +++++ D++HKC +D+DVII TA +N L+ + + TDF+L+++DE HH K+ YNKL+ Y +R + K +L +I+GLTASP F K E + + +L I++ + ++L N + +V+ +G+ K+L K L T F F + +E++V + L + ++ E + +K + + +R+ S+L H V + +A + + +KF I + + T + +F+ + + +L H + EN + + EI+K+ +R I + R+ N + + FQ + G G ++ K M+ EQ++ ++ R+ + ++++TSV +EG+D+PQC++V+ T+ A+VQ RGRAR +DS L R ++T +IL +LM
Sbjct: 1 MELHDYQWEVIAPALEGKNIIIWLPTGAGKTRAALYVAMRHLEMKRNAKVAFIVNKVHLVDQHFSNEFQPHLKD---------------KYTVVAISG---DTEHKCFFAQKTQDNDVIICTAQILQNALSSGSEEMHVELTDFTLLIIDECHHTHKDGVYNKLM---EGYLERKICRKGKL------------------------PQILGLTASPGTGRATSFHKAVEHILQICANLDTWRIMSAEVHREDLEAKAKQPNKQYDLVAQRTRDPFGDKLKELMKTIHGYLRTAEFSESEFGTQVYEQKV------VELEKEGAV---EADRMKRTCA---LHLRKYNDSLLVH--DTVRMTDAYELLAEFYVTEKF--IRKQNDPTDTFLIQLFD-RNQATLLELAHDSRFENPKLTKLEEILKDQFQFSSVSRGI-IFTRTRQSTHSLHNWISGKDY---FQKMGIKTAPLTGAGYSNQSKHMTQNEQREVIEKFRKGQLNLLVSTSVAEEGLDIPQCNVVVRYGLMTNEIAMVQARGRARHEDSCYSFLAKSGGKEIRREQTNEILEDLM 506
BLAST of Dicer-like protein 1 vs. Ensembl Xenopus
Match: gaa (glucosidase, alpha; acid [Source:Xenbase;Acc:XB-GENE-6054131]) HSP 1 Score: 116.316 bits (290), Expect = 3.363e-26 Identity = 148/572 (25.87%), Postives = 264/572 (46.15%), Query Frame = 2
Query: 905 LEPRKYQLEIYEKA-NGKDCVIFLPTGTGKTFIAAMLMLKMLEENPFHRVAFLVDKVLLVMQQ-SKSFKGQFEDICLERFESQEKTVTRKLKLISLANEIIDSDHKC----SIRDHDVIIATADFFKNILN----KQQIYWTDFSLVVLDEAHHCVKEHPYNKLLFEYHLYPQRVLLNKNELLSVXXXXXXXXXXXXXXXXWKIRRCKIIGLTASP--SGELDFDKTYELLKALLHSLGDVGIVTVTENIDELNEFTSLTNMESRIVS------YGESEKDLRK-----LMTTNFV---FLLKKFERRVNGIGNGLILSSDTSLTIEEINNLKSQLSGLLVDVREIQKSILNHILALVDIIEAIDNIGYTIAKKKFDEILENENETVWYDNNIFNFKTISKEFQLLHQEQ-ENSSI--INEIVKECKSLQDENRTILVLVEERRDAREYKNSLEKEKLNFEFQLI----VXXXXXXXXXXXXXMSVGEQKKALDFIREKKSQIIIATSVVDEGIDLPQCDLVITVNPPTSVQALVQIRGRARKKDSRLLMLC-------RDQKTIDILHELM 2500
+E YQ E+ A GK+ +I+LPTG GKT A + ++ LE +VAF+V+KV LV Q S F+ +D K +++++ D++HKC +D+DVII TA +N L+ + + TDF+L+++DE HH K+ YNKL+ Y +R + K +L +I+GLTASP F K E + + +L I++ + ++L N + +V+ +G+ K+L K L T F F + +E++V + L + ++ E + +K + + +R+ S+L H V + +A + + +KF I + + T + +F+ + + +L H + EN + + EI+K+ +R I + R+ N + + FQ + G G ++ K M+ EQ++ ++ R+ + ++++TSV +EG+D+PQC++V+ T+ A+VQ RGRAR +DS L R ++T +IL +LM
Sbjct: 1 MELHDYQWEVIAPALEGKNIIIWLPTGAGKTRAALYVAMRHLEMKRNAKVAFIVNKVHLVDQHFSNEFQPHLKD---------------KYTVVAISG---DTEHKCFFAQKTQDNDVIICTAQILQNALSSGSEEMHVELTDFTLLIIDECHHTHKDGVYNKLM---EGYLERKICRKGKLP------------------------QILGLTASPGTGRATSFHKAVEHILQICANLDTWRIMSAEVHREDLEAKAKQPNKQYDLVAQRTRDPFGDKLKELMKTIHGYLRTAEFSESEFGTQVYEQKV------VELEKEGAV---EADRMKRTCA---LHLRKYNDSLLVH--DTVRMTDAYELLAEFYVTEKF--IRKQNDPTDTFLIQLFD-RNQATLLELAHDSRFENPKLTKLEEILKDQFQFSSVSRGI-IFTRTRQSTHSLHNWISGKDY---FQKMGIKTAPLTGAGYSNQSKHMTQNEQREVIEKFRKGQLNLLVSTSVAEEGLDIPQCNVVVRYGLMTNEIAMVQARGRARHEDSCYSFLAKSGGKEIRREQTNEILEDLM 506
BLAST of Dicer-like protein 1 vs. Ensembl Xenopus
Match: gaa (glucosidase, alpha; acid [Source:Xenbase;Acc:XB-GENE-6054131]) HSP 1 Score: 116.316 bits (290), Expect = 3.901e-26 Identity = 145/566 (25.62%), Postives = 255/566 (45.05%), Query Frame = 2
Query: 905 LEPRKYQLEIYEKA-NGKDCVIFLPTGTGKTFIAAMLMLKMLEENPFHRVAFLVDKVLLVMQQ-SKSFKGQFEDICLERFESQEKTVTRKLKLISLANEIIDSDHKC----SIRDHDVIIATADFFKNILN----KQQIYWTDFSLVVLDEAHHCVKEHPYNKLLFEYHLYPQRVLLNKNELLSVXXXXXXXXXXXXXXXXWKIRRCKIIGLTASPSG--ELDFDKTYELLKALLHSLGDVGIVTVTENIDELNEFTSLTNMESRIVS------YGESEKDLRKLMTTNFVFLLKKFERRVNGIGNGLILSSDTSLTIEEINNL--KSQLSGLLVDVREIQKSILNHILALVDIIEAIDNIGYTIAKKKFDEILENENETVWYDNNIFNFKTISKEFQLLHQEQ-ENSSI--INEIVKECKSLQDENRTILVLVEERRDAREYKNSLEKEKLNFEFQLI----VXXXXXXXXXXXXXMSVGEQKKALDFIREKKSQIIIATSVVDEGIDLPQCDLVITVNPPTSVQALVQIRGRARKKDSRLLMLC-------RDQKTIDILHELM 2500
+E YQ E+ A GK+ +I+LPTG GKT A + ++ LE +VAF+V+KV LV Q S F+ +D K +++++ D++HKC +D+DVII TA +N L+ + + TDF+L+++DE HH K+ YNKL+ Y +R + K +L +I+GLTASP F K E + + +L I++ + ++L N + +V+ +G+ K+L K + L+ E + G + L E + L + + +R+ S+L H V + +A + + +KF I + + T + +F+ + +L H + EN + + EI+K+ +R I + R+ N + + FQ + G G ++ K M+ EQ++ ++ R+ + ++++TSV +EG+D+PQC++V+ T+ A+VQ RGRAR +DS L R ++T +IL +LM
Sbjct: 1 MELHDYQWEVIAPALEGKNIIIWLPTGAGKTRAALYVAMRHLEMKRNAKVAFIVNKVHLVDQHFSNEFQPHLKD---------------KYTVVAISG---DTEHKCFFAQKTQDNDVIICTAQILQNALSSGSEEMHVELTDFTLLIIDECHHTHKDGVYNKLM---EGYLERKICRKGKL------------------------PQILGLTASPGTGRATSFHKAVEHILQICANLDTWRIMSAEVHREDLEAKAKQPNKQYDLVAQRTRDPFGDKLKELMKTIHG----YLRTAEFSESEFGTQVYEQKVVELEKEALPGLLGTTTFRTCALHLRKYNDSLLVH--DTVRMTDAYELLAEFYVTEKF--IRKQNDPTDTFLIQLFDPTLL----ELAHDSRFENPKLTKLEEILKDQFQFSSVSRGI-IFTRTRQSTHSLHNWISGKDY---FQKMGIKTAPLTGAGYSNQSKHMTQNEQREVIEKFRKGQLNLLVSTSVAEEGLDIPQCNVVVRYGLMTNEIAMVQARGRARHEDSCYSFLAKSGGKEIRREQTNEILEDLM 505
BLAST of Dicer-like protein 1 vs. Ensembl Mouse
Match: Ddx58 (DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 [Source:MGI Symbol;Acc:MGI:2442858]) HSP 1 Score: 77.0258 bits (188), Expect = 5.516e-14 Identity = 52/164 (31.71%), Postives = 83/164 (50.61%), Query Frame = 2
Query: 905 LEPRKYQLEIYEKAN-GKDCVIFLPTGTGKTFIAAMLMLKMLEENPFH---RVAFLVDKVLLVMQQSKSFKGQFEDICLERFESQEKTVTRKLKLISLANEIIDS-DHKCSIRDHDVIIATADFFKNILNKQQI-YWTDFSLVVLDEAHHCVKEHPYNKLLFEY 1378
L+PR YQLE+ A GK+ +I PTG GKTF++ ++ L++ P +V F +++ + QQ+ F FE + + S++ DS + I D+D+II T N LN I + F+L++ DE H+ K HPYN+++F Y
Sbjct: 197 LKPRNYQLELALPAKKGKNTIICAPTGCGKTFVSLLICEHHLKKFPCGQKGKVVFFANQIPVYEQQATVFSRYFERL--------------GYNIASISGATSDSVSVQHIIEDNDIIILTPQILVNNLNNGAIPSLSVFTLMIFDECHNTSKNHPYNQIMFRY 346 HSP 2 Score: 56.225 bits (134), Expect = 1.488e-7 Identity = 30/77 (38.96%), Postives = 45/77 (58.44%), Query Frame = 2
Query: 2255 MSVGEQKKALDFIREKK-SQIIIATSVVDEGIDLPQCDLVITVNPPTSVQALVQIRGRARKKDSRLLMLCRDQKTID 2482
M++ QK L+ R + I+IATSV DEGID+ +C+LVI +V ++Q RGR R +DS+ +L I+
Sbjct: 629 MTLPAQKCVLEAFRASGDNNILIATSVADEGIDIAECNLVILYEYVGNVIKMIQTRGRGRARDSKCFLLTSSADVIE 705
BLAST of Dicer-like protein 1 vs. Ensembl Mouse
Match: Ddx58 (DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 [Source:MGI Symbol;Acc:MGI:2442858]) HSP 1 Score: 76.2554 bits (186), Expect = 1.238e-13 Identity = 52/164 (31.71%), Postives = 83/164 (50.61%), Query Frame = 2
Query: 905 LEPRKYQLEIYEKAN-GKDCVIFLPTGTGKTFIAAMLMLKMLEENPFH---RVAFLVDKVLLVMQQSKSFKGQFEDICLERFESQEKTVTRKLKLISLANEIIDS-DHKCSIRDHDVIIATADFFKNILNKQQI-YWTDFSLVVLDEAHHCVKEHPYNKLLFEY 1378
L+PR YQLE+ A GK+ +I PTG GKTF++ ++ L++ P +V F +++ + QQ+ F FE + + S++ DS + I D+D+II T N LN I + F+L++ DE H+ K HPYN+++F Y
Sbjct: 242 LKPRNYQLELALPAKKGKNTIICAPTGCGKTFVSLLICEHHLKKFPCGQKGKVVFFANQIPVYEQQATVFSRYFERL--------------GYNIASISGATSDSVSVQHIIEDNDIIILTPQILVNNLNNGAIPSLSVFTLMIFDECHNTSKNHPYNQIMFRY 391 HSP 2 Score: 56.6102 bits (135), Expect = 1.463e-7 Identity = 30/77 (38.96%), Postives = 45/77 (58.44%), Query Frame = 2
Query: 2255 MSVGEQKKALDFIREKK-SQIIIATSVVDEGIDLPQCDLVITVNPPTSVQALVQIRGRARKKDSRLLMLCRDQKTID 2482
M++ QK L+ R + I+IATSV DEGID+ +C+LVI +V ++Q RGR R +DS+ +L I+
Sbjct: 674 MTLPAQKCVLEAFRASGDNNILIATSVADEGIDIAECNLVILYEYVGNVIKMIQTRGRGRARDSKCFLLTSSADVIE 750
BLAST of Dicer-like protein 1 vs. Ensembl Mouse
Match: Dhx58 (DEXH (Asp-Glu-X-His) box polypeptide 58 [Source:MGI Symbol;Acc:MGI:1931560]) HSP 1 Score: 74.7146 bits (182), Expect = 3.080e-13 Identity = 54/164 (32.93%), Postives = 84/164 (51.22%), Query Frame = 2
Query: 905 LEPRKYQLEIYEKA-NGKDCVIFLPTGTGKTFIAAMLMLKMLEENPFHRVAFLVDKVLLVMQQSKSFKGQFEDICLERFESQEKTVTRKLKLISLANEIID-SDHKCSIRDHDVIIATADFFKNILNK----QQIYWTDFSLVVLDEAHHCVKEHPYNKLLFEY 1378
+E R YQ E+ A GK+ +I+LPTG GKT AA + + LE +V LV++V LV Q ++ F+ R + TVT +L+ ++ + R HD++I TA+ + LN + + +FSL+V+DE HH K+ YN +L Y
Sbjct: 1 MELRPYQWEVILPALEGKNIIIWLPTGAGKTRAAAFVAKRHLETVDRGKVVVLVNRVHLVSQHAEEFR---------RMLDKHWTVT------TLSGDMGSRAGFGLMARSHDLLICTAELLQLALNSSEEDEHVELREFSLIVVDECHHTHKDTVYNTILSRY 149
BLAST of Dicer-like protein 1 vs. Ensembl Mouse
Match: Ifih1 (interferon induced with helicase C domain 1 [Source:MGI Symbol;Acc:MGI:1918836]) HSP 1 Score: 71.2478 bits (173), Expect = 4.042e-12 Identity = 76/260 (29.23%), Postives = 125/260 (48.08%), Query Frame = 2
Query: 902 KLEPRKYQLEIYEKA-NGKDCVIFLPTGTGKTFIAAMLMLKMLEE----NPFHRVAFLVDKVLLVMQQSKSFKGQFEDICLERFESQEKTVTRKLKLISLANEIIDSDHKCS----IRDHDVIIATADFFKNIL------NKQQIYWTDFSLVVLDEAHHCVKEHPYNKLLFEYHLYPQRVLLNKNELLSVXXXXXXXXXXXXXXXXWKIRRCKIIGLTASPSGELDFDKTYELLKALLH---SLGDVGIVTVTENIDEL 1627
+L+ R YQ+E+ + A +GK+ +I LPTG+GKT +A + L++ + +V LV+KV+L Q F+ +F + + ++I L+ D+ K S ++ +DVII+TA +N L + + +DFSL+++DE HH KE YN ++ Y + L N+L + + I +I+GLTASP G K E K +L+ +L I TV EN+ +L
Sbjct: 306 ELQLRPYQMEVAQPALDGKNIIICLPTGSGKTRVAVYITKDHLDKKKQASESGKVIVLVNKVMLAEQL---FRKEFNPY-----------LKKWYRIIGLSG---DTQLKISFPEVVKSYDVIISTAQILENSLLNLESGDDDGVQLSDFSLIIIDECHHTNKEAVYNNIMRRY----LKQKLRNNDL--------------KKQNKPAIPLPQILGLTASP-GVGAAKKQSEAEKHILNICANLDAFTIKTVKENLGQL 529 HSP 2 Score: 51.9878 bits (123), Expect = 3.691e-6 Identity = 25/68 (36.76%), Postives = 44/68 (64.71%), Query Frame = 2
Query: 2255 MSVGEQKKALDFIREKKSQIIIATSVVDEGIDLPQCDLVITVNPPTSVQALVQIRGRARKKDSRLLML 2458
M+ EQK+ + R + ++IAT+V +EG+D+ +C++VI T+ A+VQ RGRAR +S +++
Sbjct: 766 MTQTEQKEVISKFRTGEINLLIATTVAEEGLDIKECNIVIRYGLVTNEIAMVQARGRARADESTYVLV 833
BLAST of Dicer-like protein 1 vs. Ensembl Mouse
Match: Ifih1 (interferon induced with helicase C domain 1 [Source:MGI Symbol;Acc:MGI:1918836]) HSP 1 Score: 71.2478 bits (173), Expect = 4.099e-12 Identity = 76/260 (29.23%), Postives = 125/260 (48.08%), Query Frame = 2
Query: 902 KLEPRKYQLEIYEKA-NGKDCVIFLPTGTGKTFIAAMLMLKMLEE----NPFHRVAFLVDKVLLVMQQSKSFKGQFEDICLERFESQEKTVTRKLKLISLANEIIDSDHKCS----IRDHDVIIATADFFKNIL------NKQQIYWTDFSLVVLDEAHHCVKEHPYNKLLFEYHLYPQRVLLNKNELLSVXXXXXXXXXXXXXXXXWKIRRCKIIGLTASPSGELDFDKTYELLKALLH---SLGDVGIVTVTENIDEL 1627
+L+ R YQ+E+ + A +GK+ +I LPTG+GKT +A + L++ + +V LV+KV+L Q F+ +F + + ++I L+ D+ K S ++ +DVII+TA +N L + + +DFSL+++DE HH KE YN ++ Y + L N+L + + I +I+GLTASP G K E K +L+ +L I TV EN+ +L
Sbjct: 257 ELQLRPYQMEVAQPALDGKNIIICLPTGSGKTRVAVYITKDHLDKKKQASESGKVIVLVNKVMLAEQL---FRKEFNPY-----------LKKWYRIIGLSG---DTQLKISFPEVVKSYDVIISTAQILENSLLNLESGDDDGVQLSDFSLIIIDECHHTNKEAVYNNIMRRY----LKQKLRNNDL--------------KKQNKPAIPLPQILGLTASP-GVGAAKKQSEAEKHILNICANLDAFTIKTVKENLGQL 480 HSP 2 Score: 51.9878 bits (123), Expect = 3.378e-6 Identity = 25/68 (36.76%), Postives = 44/68 (64.71%), Query Frame = 2
Query: 2255 MSVGEQKKALDFIREKKSQIIIATSVVDEGIDLPQCDLVITVNPPTSVQALVQIRGRARKKDSRLLML 2458
M+ EQK+ + R + ++IAT+V +EG+D+ +C++VI T+ A+VQ RGRAR +S +++
Sbjct: 717 MTQTEQKEVISKFRTGEINLLIATTVAEEGLDIKECNIVIRYGLVTNEIAMVQARGRARADESTYVLV 784
BLAST of Dicer-like protein 1 vs. UniProt/SwissProt
Match: sp|O95786|DDX58_HUMAN (Antiviral innate immune response receptor RIG-I OS=Homo sapiens OX=9606 GN=DDX58 PE=1 SV=2) HSP 1 Score: 98.9821 bits (245), Expect = 8.274e-20 Identity = 143/563 (25.40%), Postives = 243/563 (43.16%), Query Frame = 2
Query: 905 LEPRKYQLEIYEKA-NGKDCVIFLPTGTGKTFIAAMLM---LKMLEENPFHRVAFLVDKVLLVMQQSKSFKGQFEDICLERFESQEKTVTRKLKLISLANEIIDSDHKCSIRDHDVIIATADFFKNILNKQQI-YWTDFSLVVLDEAHHCVKEHPYNKLLFEYHLYPQRVLLNKNELLSVXXXXXXXXXXXXXXXXWKIRRCKIIGLTASPS-GEL-DFDKTYELLKALLHSLGDVGIVTVTENIDELNEFTS-----LTNMESRI---VSYGESE-------------KDLRKL-MTTNFVFLLKKFERRVNGIGNGLILSSDTSLTIEEINNLKSQLSGLLVDVREIQKS----ILNHILALVDIIEAIDNIGYTIAKKKFDEILENENETVWYDNNIFNFKTISKEFQLLHQEQENSSI--INEIVKECKSLQDENRTILVLVEERRDAREYKNSLE-KEKLNFEFQLIVXXXXXXXXXXXXXMSVGEQKKALD-FIREKKSQIIIATSVVDEGIDLPQCDLVITVNPPTSVQALVQIRGRARKKDSRLLMLCRDQKTID 2482
+PR YQLE+ A GK+ +I PTG GKTF++ ++ LK + +V F +++ + QQ F FE + R + E + + + ++D+II T N L K I + F+L++ DE H+ K+HPYN ++F Y Q++ + L V IGLTAS G+ + D+ + + L SL I TV N++EL + +ESRI Y ++ KDL L N F +K+E+ + + ++ + + + L + ++K I++ + D ++ + + + FDEI ++ T ++ + +++S++ EN + + I++E L E TIL V+ R KN +E KL+F I+ G+G +++ GM++ QK LD F I+IATSV DEGID+ QC+LVI +V ++Q RGR R + S+ +L + I+
Sbjct: 241 FKPRNYQLELALPAMKGKNTIICAPTGCGKTFVSLLICEHHLKKFPQGQKGKVVFFANQIPVYEQQKSVFSKYFE-----------RHGYRVTGISGATAENVPVEQ--IVENNDIIILTPQILVNNLKKGTIPSLSIFTLMIFDECHNTSKQHPYNMIMFNY--LDQKLGGSSGPLPQV------------------------IGLTASVGVGDAKNTDEALDYICKLCASLDASVIATVKHNLEELEQVVYKPQKFFRKVESRISDKFKYIIAQLMRDTESLAKRICKDLENLSQIQNREFGTQKYEQWIVTVQKACMV-----FQMPDKDEESRICKALFLYTSHLRKYNDALIISEHARMKDALDYLKDFFSNVRAAGFDEI--EQDLTQRFEEKLQELESVSRD-----PSNENPKLEDLCFILQEEYHLNPETITIL-FVKTRALVDALKNWIEGNPKLSFLKPGIL--TGRGKTNQNTGMTLPAQKCILDAFKASGDHNILIATSVADEGIDIAQCNLVILYEYVGNVIKMIQTRGRGRARGSKCFLLTSNAGVIE 749
BLAST of Dicer-like protein 1 vs. UniProt/SwissProt
Match: sp|Q09884|DCR1_SCHPO (Protein Dicer OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=dcr1 PE=1 SV=1) HSP 1 Score: 98.9821 bits (245), Expect = 9.381e-20 Identity = 146/554 (26.35%), Postives = 232/554 (41.88%), Query Frame = 2
Query: 914 RKYQLEIYEKANGKDCVIFLPTGTGKTFIAAMLMLKMLEE-------NPFHR--VAFLVDKVLLVMQQSKSFKGQFEDICLERFESQEKTVTRKLKLISLANEIIDSDHKCSIRDHDVIIATADFFKNILNKQQIYWTDFSLVVLDEAHHCVKEHPYNKLLFEYHLYPQRVLLNKNELLSVXXXXXXXXXXXXXXXXWKIRRCKIIGLTASP----SGELDFDKTYELLKALLHSLGDVGIVTVTENIDELNEFTSLTNMESRIVSYGESEKDLRKLMTTNFVFLLKKFERRVNG-------IGNGLILSSDTSLTIEEINNLKSQLSGLLVDVRE---IQKSILNHILALVDIIEAIDNIGYTIAKKKFDEILENENETVWYDNNIFNFKTISKEFQLLHQEQENSSIINEIVKECKSLQDENRTILVLVEERRDAREYKNSLEKEKLNFE-FQLIVXXXXXXXXXXXXXMSVGEQKKALDFIREKKSQIIIATSVVDEGIDLPQCDLVITVNPPTSVQALVQIRGRARKKDSRLLMLCRDQKTI---DILHE 2494
RKYQ ++Y A+ ++ ++ + TG GKT +A L+ + LEE N H+ FLV+KV LV QQ++ + Q + ++ +L L N I+ ++VI+ TAD F L + + D +L++ DE HH + Y +++ +++ + VL K+ L +I G+TASP G L + + Y+ L D V+EN EL ++ L E V Y KL+ ++KK E + G + L + D L E Q+ LVD E ++K L L+ D AID + + K ++ +N +D+ K F+LL E++K D RT+ + VE R A + SL + LN + G + M+ QK L + K ++IAT+V +EGID+P C+LVI N +V VQ RGRAR S+ L+ ++ + ILHE
Sbjct: 13 RKYQQDVYNIASKQNTLLVMRTGAGKTLLAVKLIKQKLEEQILIQESNLEHKKISVFLVNKVPLVFQQAEYIRSQLPAKVGMFYGELSIEMSEQL----LTNIILK---------YNVIVITADLFYLFLARGFLSINDLNLIIFDECHHAIGNDAYARIMNDFYHRAKAVLSKKHFTLP-----------------------RIFGMTASPFTGKKGNL-YHRLYQ-----WEQLFDSKAHVVSEN--ELADYFCLP--EESYVMYSN------KLVVPPSDSIIKKCEETLQGCKLISRAVKTALAETIDMGLWFGE------QVWLYLVDFVETKRLKKKALGKQLS-DDEELAIDRLKIFVEDWKNNKYSDNGPRIPVFDST----DVTDKVFKLL-----------ELLKATYRKSDSVRTV-IFVE--RKATAFTLSLFMKTLNLPNIRAHSFIGHGPSDQGEFSMTFRRQKDTLHKFKTGKYNVLIATAVAEEGIDVPSCNLVIRFNICRTVTQYVQSRGRARAMASKFLIFLNTEELLIHERILHE 489
BLAST of Dicer-like protein 1 vs. UniProt/SwissProt
Match: sp|Q7S8J7|DCL1_NEUCR (Dicer-like protein 1 OS=Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987) OX=367110 GN=dcl-1 PE=2 SV=1) HSP 1 Score: 92.4337 bits (228), Expect = 1.301e-17 Identity = 73/236 (30.93%), Postives = 112/236 (47.46%), Query Frame = 2
Query: 911 PRKYQLEIYEKANGKDCVIFLPTGTGKTFIAAMLM-------LKMLEENPFHRVAF-LVDKVLLVMQQ----SKSFKGQFEDICLERFESQEKTVTRKLKLISLANEIIDSDHKCSIRDHDVIIATADFFKNILNKQQIYWTDFSLVVLDEAHHCVKEHPYNKLLFEYHLYPQRVLLNKNELLSVXXXXXXXXXXXXXXXXWKIRRCKIIGLTASP-SGELDFDKTYELLKALLHS 1579
PR+YQ+E++E+A ++ + L TG+GKT IAAML+ L+ E+ R+AF LVDKV LV QQ +K+ E +C E E E K L ++V++ TA+ L+ I +L++ DEAHH K+HPY +++ +++ +E L RR +I+GLTASP ++D + L+ALLHS
Sbjct: 122 PREYQVELFERAKQQNTIAVLDTGSGKTLIAAMLLRWVITGELEDREKGLPRRIAFFLVDKVALVFQQHSFLTKNLDFPMEKLCGEMVEGVESKAFWKEAL----------------EQNEVVVCTAEILSTALHHSWIRMDQINLLIFDEAHHTKKDHPYARIIKNFYI---------DEQLE--------------------RRPRILGLTASPVDAKVDPRRAAAELEALLHS 312
BLAST of Dicer-like protein 1 vs. UniProt/SwissProt
Match: sp|Q2VF19|DCL1_CRYPA (Dicer-like protein 1 OS=Cryphonectria parasitica OX=5116 GN=DCL-1 PE=3 SV=1) HSP 1 Score: 80.4925 bits (197), Expect = 5.605e-14 Identity = 68/233 (29.18%), Postives = 101/233 (43.35%), Query Frame = 2
Query: 911 PRKYQLEIYEKANGKDCVIFLPTGTGKTFIAAMLMLKMLEEN--------PFHRVAFLVDKVLLVMQQSKSFKGQFE-DICLERFESQEKTVTRKLKLISLANEIIDSDHKCSIRDHDVIIATADFFKNILNKQQIYWTDFSLVVLDEAHHCVKEHPYNKLLFEYHLYPQRVLLNKNELLSVXXXXXXXXXXXXXXXXWKIRRCKIIGLTASPSGEL-DFDKTYELLKALLHS 1579
PR YQ+E++E+A ++ + L TG+GKT IAA+L+ + + P FLV+KV L QQ + + + ES + T T+ LA DH+VI+ TA+ L I +L+V DEAHH K HPY +++ +Y+ K+ L R +I G+TASP L D + L+ LLHS
Sbjct: 99 PRDYQMELFERAKQQNTIAVLDTGSGKTLIAALLLDHTVNQELEDRAKGLPRRIAFFLVEKVALAFQQHAVLECNLAHSVAVFSGESIKNTWTKGFWETQLA-------------DHEVIVCTAEILNQCLQYAYIRIDQINLLVFDEAHHTKKNHPYARIIKDYYAS------GKDRGL---------------------RLPRIFGMTASPVDALIDVRQAAIELEGLLHS 291
BLAST of Dicer-like protein 1 vs. UniProt/SwissProt
Match: sp|A2R345|DCL21_ASPNC (Dicer-like protein 2-1 OS=Aspergillus niger (strain CBS 513.88 / FGSC A1513) OX=425011 GN=dcl2-1 PE=3 SV=2) HSP 1 Score: 80.1073 bits (196), Expect = 7.127e-14 Identity = 56/204 (27.45%), Postives = 100/204 (49.02%), Query Frame = 2
Query: 911 PRKYQLEIYEKANGKDCVIFLPTGTGKTFIAAMLMLKMLEENPFHRVAFLVDKVLLVMQQSKSFKGQFEDICLERFESQEKTVTRKLKLISLANEIIDSDHKCSIRDHDVIIATADFFKNILNKQQIYWTDFSLVVLDEAHHCVKEHPYNKLLFEYHLYPQRVLLNKNELLSVXXXXXXXXXXXXXXXXWKIRRCKIIGLTASP 1522
PR YQ+E++E + ++ ++ + TG+GKT IA + ++K LE NP + FL V L +QQ K + + +T+T L + L E D +++ V+++T + ++ + T L++ DEAHHC++ HP NK++ +++ +P L ++ +V KI+GLTASP
Sbjct: 19 PRSYQVEMFEASLKENIIVTMGTGSGKTHIALLRIIKELESNPHKLIWFLTPTVALCLQQFKFLSDNIPAV-------RARTLT-SLDKVELWTEQPVWD--AILKEMQVVVSTHAVLADAMSHGFVKITQLGLMIFDEAHHCMRRHPANKIMQDFY-HPA---LERHGAEAVP---------------------KILGLTASP 187
BLAST of Dicer-like protein 1 vs. TrEMBL
Match: A0A1S3HGS0 (uncharacterized protein LOC106154762 OS=Lingula unguis OX=7574 GN=LOC106154762 PE=4 SV=1) HSP 1 Score: 243.047 bits (619), Expect = 8.056e-64 Identity = 196/659 (29.74%), Postives = 328/659 (49.77%), Query Frame = 2
Query: 593 CLLCQTKMNTDEQYAMHCSGSKHTKKIRSFNLSDHFILKEESYNEEMIDCKICNIKIH-RNNQDSHDKGKMHRDNLFKSKTEDIISQTVRKTELSD-GLKNLKLLKLE-PRKYQLEIYEKANGKDCVIFLPTGTGKTFIAAMLMLKMLEENPFHRVAFLVDKVLLVMQQSKSFKGQFEDICLERFESQEKTVTRKLKLISLANEIIDSDHKCSIRDHDVIIATADFFKNILNKQQIYWTDFSLVVLDEAHHCVKEHPYNKLLFEYHLYPQRVLLNKNELLSVXXXXXXXXXXXXXXXXWKIRRCKIIGLTASPSGELDFDKTYELLKALLHSLGDVGIVTVTEN---IDELNEFTSLTNMESRIVSYGESEKDLRKLMTTNFVFLLKKFERRVNGIGNGLILSSDTSLTIEEINNLKSQL----SGLLVDVREIQ-------KSILNHILALVDIIEAIDNIGYTIAKKKFDEILENENETVWYDNNIFNF-----KTISKEFQLLHQEQENS------SIINEIVKEC---KSLQDENRTILVLVEERRDAREYKNSL-EKEKL-NFEFQLIVXXXXXXXXXXXXXMSVGEQKKALDFIREKKSQIIIATSVVDEGIDLPQCDLVITVNPPTSVQALVQIRGRARKKD-SRLLMLCRD 2467
C +C +++ + + H G H K++ S + + L ++ + C C + + H + + H+ L +S+ S + E+ D + L+ PR YQ+++YE A D V+FLPTGTGKT I+AM++ ML+ NP V FLVD+VLLVMQQSK K + D R + + R+LK+ +L E D+ + I D+++ TA ++ N+L KQ + W D L V DEAHHCVK HP+N+LL ++H R L K+ R KI+GLTASP+G + T ++LK LL ++GD + + EN EL+++ + T + ++ + +EK+L+ + ++FL GN D+ ++ +LK + L D + I+ +++ H L + + A+ + A + ++L + + N K++++ F L +E++ ++ EI++ Q + +LVLV+ R A++ +L E E+L + G G S GM++ +Q +AL+ IR + Q+++ATSV +EG+D P+C+LVI +NPP+SV ALVQ RGRARK+ SR + LCR+
Sbjct: 341 CFICNVGLDSRIKSSQHFRGKNHAKQL-SRAKNGYLQL---TFVPGLYSCSECQVNFSGPESHAQHLQSEKHKAKLAQSQCVPERSLPLHVKEVVDCDMDPYSLMTTTLPRSYQIDLYEAAMKGDVVVFLPTGTGKTVISAMVVSHMLQLNPARPVVFLVDRVLLVMQQSKVLKTELGDKMYTRIDDGVQH-DRQLKIGTLCGEKQDTGGEL-IWKQDIVVTTAAYYLNLLEKQVVCWQDLCLAVFDEAHHCVKSHPFNRLLEQFH----RKLQLKH-------------------------RPKILGLTASPAGRETVEDTEKMLKRLLENIGDGKLAAIMENDRSFKELSKYKTQTKLIAKELGLTVNEKELQDEL-QKYLFLCYNRLSVETDFGN-----FDSREEVKTCQDLKGDVLEAFQIFLQDAKPIEPDRNIYIEALKLHCSVLCEALSAVGDGSVEFAFRVLQDLLNRSHPGSFEKAAELNLAHQKVKSLTEHFALRTEEEKEDDKMAVKTVAREILQGIDWDSREQGKQPFVLVLVKTRVVAQQMTEALKEMEELKECGICPVCIVGHGGGSSDGGGMTIKKQSRALEGIRNYEYQVVVATSVAEEGVDFPECELVIHMNPPSSVTALVQTRGRARKQGVSRFIALCRE 958
BLAST of Dicer-like protein 1 vs. TrEMBL
Match: A0A210PZ85 (Endoribonuclease Dicer-like 3a OS=Mizuhopecten yessoensis OX=6573 GN=KP79_PYT18042 PE=4 SV=1) HSP 1 Score: 230.335 bits (586), Expect = 9.028e-59 Identity = 195/652 (29.91%), Postives = 317/652 (48.62%), Query Frame = 2
Query: 740 CKICNIKI--HRNNQDSHDKGKMHRDNLFKSKTEDIISQTV----RKTELSDGLKNLKLLKLEPRKYQLEIYEKANGKDCVIFLPTGTGKTFIAAMLMLKMLEENPFHRVAFLVDKVLLVMQQSKSFKGQFEDICLERFESQE--KTVTRKLKLISLANEIIDSDHKCSIRDHDVIIATADFFKNILNKQQIYWTDFSLVVLDEAHHCVKEHPYNKLLFEYHLYPQRVLLNKNELLSVXXXXXXXXXXXXXXXXWKIR---RCKIIGLTASPSGELDFDKTYELLKALLHSLGDVGIVTVTENIDELNEFTSLTNMESRIVSYGESEKDLRKLMTTNFVFLLKKFERRVNGI-----GNGLILSSDTSLTIEEINNLKSQLSGLLVDVREIQ-------------------KSILNHILALVDIIEAIDNIGYTIAKKKFDEILE-NENETVWYDNNI-FNFKTI--SKEFQLLHQE-----------QENSSIINEIVK--------ECKSLQDENRTI-LVLVEERRDAREYKNSLE------KEKLNFEFQLIVXXXXXXXXXXXXXMSVGEQKKALDFIREKKSQIIIATSVVDEGIDLPQCDLVITVNPPTSVQALVQIRGRARKKDSRLLMLCRDQKTIDILHELM 2500
C C + + + QD H KGK+HR KS E S+ + + + + PR YQ E++ K D + FLPTGTGKT I M + ML+ NP H+V FLV KVLLV+QQ K + Q + RF+ + KTV R+LK+ L S + HD+I+ATA + +N+L + + W D LV+ DEAHHC K H YN L+ +H +KI RCKI+GLTASP+G+ ++ T ++L+ L ++GD I V ++L + S + ++ +E+ ++ + V+LL+ + R N + + S++++++ ++G ++D E+Q ++++ HI + I +G A ++ E++ N N+ + I + I S E Q L Q+ QE SS + ++K + Q +++ + LVLV+ R A +L K KL+ E + G GA + KGMSV +Q+K L+ I++ K Q++IAT+V +EGIDLP+C+LV+++NPP+++ ALVQ+RGRARK +S +++C D K L +L+
Sbjct: 1035 CPTCKVPMDTEKALQD-HLKGKLHR---MKSAKEPACSRQLPPLTKTISAPFPQEQNNFTETIPRNYQWELFHKVMTGDRICFLPTGTGKTLIGCMAIGAMLDLNPSHQVLFLVTKVLLVLQQGKYIRNQLANRKYRRFDPNDPSKTVERELKIAELCGG-QQSTGGVPLWQHDIIVATAAYCENMLTNKVLRWQDQCLVIFDEAHHCSKNHSYNNLMATHH--------------------------------YKINESFRCKILGLTASPAGKNNYSMTVDMLRQLQINMGDSLIAIVEYEKEKLKAYMSNAKIHIAVMETTPAEEQFQRDLR---VYLLQCYMRLAAETNIFEHSNLGLTGTSKSVSVQDLQRHAQDITGDVLD--ELQALIAMAKPNTSSVDKRIEVQNLIGHIKCICMTISVAMEMGIPQALEEMQELMATNLNQDFDFARQIGLPCQDILHSIEAQQLFQKSNLKVLDESISQEMSSNVKCLIKQLIYENYIQWNGGQGQSQQLALVLVKRRATATALHETLMNHPEIVKRKLSVEKMV-----GHGAAAAEKGMSVAQQRKTLEEIKDHKYQVVIATAVAEEGIDLPECELVVSMNPPSTMTALVQMRGRARKLNSHFVIVCNDSKEEAKLSDLL 1639
BLAST of Dicer-like protein 1 vs. TrEMBL
Match: A0A2B4RFJ4 (Dicer-like protein 1 OS=Stylophora pistillata OX=50429 GN=dcl1 PE=4 SV=1) HSP 1 Score: 215.312 bits (547), Expect = 3.332e-54 Identity = 189/667 (28.34%), Postives = 307/667 (46.03%), Query Frame = 2
Query: 581 NWITCLLCQTKMNTDEQYAMHCSGSKHTKKIRSFNLSDHFILKEESYNEEMIDCKICNIKIHRNNQ-DSHDKGKMHRDNLFKSKTEDIISQTVRKTELSDGLKNLKLLKL------------EPRKYQLEIYEKANGKDCVIFLPTGTGKTFIAAMLMLKMLEENPFHRVAFLVDKVLLVMQQSKSFKGQFEDICL--ER--FESQEKTVTRKLKLISLANEIIDSDHKCSIRDHDVIIATADFFKNILNKQQIYWTDFSLVVLDEAHHCVKEHPYNKLLFEYHLYPQRVLLNKNELLSVXXXXXXXXXXXXXXXXWKIRRCKIIGLTASPSGELDFDKTYELLKALLHSLGDVGIVTVTENIDELNEFTSLTNMESRIVSYGESEKDLRKLMTTNFVFLLKKFERRVN-----GIGNGLILSSDTSLTIEEINNLKSQLSGLLVDVREIQK-SILNHILALVDIIEAIDNIGYTIAKKKFDEILEN--ENETVWYDNNIFNFKTISKEFQLLHQEQENSSIINEIVKECKSLQDE-------------NRTILVLVEERRDAREYKNSLEKEKLNFEFQLIVXXXXXXXXXXXXXMSVGEQKKALDFIREKKSQIIIATSVVDEGIDLPQCDLVITVNPPTSVQALVQIRGRARKKDSRLLMLCRD 2467
+W C LC+ ++ QY H +KH K+ F+ SY + C+ CN+ ++ +Q + H H QTV K++ + ++L L+K +P Y +E+Y KA + V FLPTGTGKT +AA ++ ML+ NP +V FLVD+VLLV+QQS + + I + ER FES TR +++ ++ E+ + I + DV+I TAD ++N LN + + D SL+VLDEAHHC K+HPYN ++ +++L + V L R KI+GLTASP+GE +KT + L+ LL +LGD ++ VT N EL E T+ + SY E+DL ++ ++ K F V + SS +I++I + + +L E + L H L + + + GY IA + E+ + + W ++ + + + L+ Q SII + L ++ N LVLV+ + AR L ++ + + +S KG++ + IRE K QI++ TS+ +EG+DLP+ V ++P + V AL +IRGRA +R + + R+
Sbjct: 423 SWTYCRLCKFSFASESQYEEHLRSTKHQNKVAKFS--------PISYKKY---CEYCNVHLNSESQANEHFNSARH-------------EQTVAKSQKAPPQQHLPLIKAPKEFVMEQFTRTQPFNYHIELYSKAMLTNGVCFLPTGTGKTLVAAQVIAHMLKLNPSRQVVFLVDRVLLVLQQSDCLRKELGHIRVADERGSFES-----TRPIRIGAVCGEMRKLEGNARIYEQDVLIITADCYRNHLNNGTLRFDDVSLIVLDEAHHCNKDHPYNVIIRDFYLQ-EDVHLG--------------------------HRPKILGLTASPAGETSLEKTTKRLQRLLGNLGDAELLVVTRNGQELEEKTNRATPDCISASYTTHERDLLDILVK---YVTKAFNLTVRLSDMKDYKDIFQPSSGGPFSIDDIYPVLGVIDNILQSQPEANALNALLHFQLLCEAVCTLQECGYQIALYQMTELAQEACPHGFHWAESMGLPCGEV-RAYLELYLRQGFPSIIERRNSGAERLMEQLVRVNWNGVIGRSNCLALVLVKRQHTARCLSKYLSNQR-ELTSRGVRTTFINAGRSADKGLAYPLEIDPFVQIREGKFQIVVTTSLAEEGLDLPEPQWVFQMDPSSPVLALREIRGRAPLNGARFVAISRN 1028
BLAST of Dicer-like protein 1 vs. TrEMBL
Match: A0A0L8GKZ1 (Uncharacterized protein OS=Octopus bimaculoides OX=37653 GN=OCBIM_22031992mg PE=4 SV=1) HSP 1 Score: 200.675 bits (509), Expect = 1.408e-50 Identity = 211/754 (27.98%), Postives = 338/754 (44.83%), Query Frame = 2
Query: 338 ESHNKGKLHLKK-SMKNDFIHFKCDETPIQNQFSNEANLVRSSENIDIVKPYEVLSMNENETNKPSDISPDILNLLKPHKEGNWITCLLCQTKMNTDEQYAMHCSGSKHTKKIRSFNLS-DHFILKEESYNEEMID--CKICNIKIH-RNNQDSHDKGKMHRDNLFKSKT------------EDIISQTVRKTELSDGLKNLKLLKLEPRKYQLEIYEKANGKDCVIFLPTGTGKTFIAAMLMLKMLEENPFHRVAFLVDKVLLVMQQSKSFKGQFEDICLERFESQ--EKTVTRKLKLISLANEIIDSDHKCSIRD----HDVIIATADFFKNILNKQQIYWTDFSLVVLDEAHHCVKEHPYNKLLFEYHLYPQRVLLNKNELLSVXXXXXXXXXXXXXXXXWKIRRC-KIIGLTASPSGELDFDKTYELLKALLHSLGDVGIVTVTENIDELNEFTSLTNMESRIVSYGESE----KDLRKLMTTNFVFLLKKFERRVNGIGNGLILSSDTSLTIEEINNLKSQLSGLLVDVREIQKS--ILNHILALVD-IIEAIDN-IGYTIAKKKFDEILEN--------ENETVWYDN--NIFNFKTISKEFQLLHQEQENSSIINEIVKECKSLQDENRTILVLVEERRDAREYKNSLEKEKLNFEFQLIVXXXXXXXXXXXXXMSVGEQKKALDFIREKKSQIIIATSVVDEGIDLPQCDLVITVNPPTSVQALVQIRGRARKKDSRLLMLCRDQK 2473
ESH KGK H KK S + F C PI+ Q + +N+ + + PY ++ E P + N ++ + Q C ++ +R +L + FI + ++E+I C +C+ K+ + SH + H N+ + + ED I + L+D + PR YQ+E++EK+ D +IFLPTGTGKT V F+VDKVLL +QQ + + +D RF++ E + R LK+I + H S ++ HDVII+TA + + + + W DFSLVV+DE HH KEHP+ KLL E H + C +++GLTASP+G+ KT +L+ L+ +L + I V E + EL ++ S ++ V + ++E + +K + L+ F+ + +I SS+ + +N ++ +L + + + E++K ++NH +V II+A+D I + + KF N + DN ++ N +S + Q I E + + + + + ILV+V+ RR A E ++ L E +L V GM V Q+K I+E K QIII TSV +EG+DLP+C LVIT+NPPTSV LVQ+RGRARK +S L++C + K
Sbjct: 25 ESHLKGKKHQKKFSERERF----CTSLPIR-QVESPSNVQPVHAALSNIPPYNTEAITE------------------PTRSQN----------VSINVQTTQTCKEDENIVSLRPTSLDRNEFIRIYKDEDDEIIGYKCTLCSKKLQCASAVTSHLQSSAHCKNVSEQPSKLYNLPPIVHHCEDPIDEAYC---LTDSI---------PRGYQVELFEKSYCYDSIIFLPTGTGKTXXXXR-----------RPVLFIVDKVLLALQQFNYIQNELKDQKFSRFDTTNIENIIERNLKIIC-----VYGGHPGSAKEPLSMHDVIISTAVYCDLRMKENVLRWKDFSLVVIDEVHHSDKEHPFRKLLKEEH------------------------------HTLEETDCPQLLGLTASPAGKETIPKTITMLQTLVTNLNNSKINIVKEEVKELMKYKSSAQLKICTVPFQDAELPYIAEFKKYLLECLKVLVDYFD-----LSQYIIPSSEDLIDKSFLNEIEERLRSVTI-IGEMEKGTILINHTKEIVSLIIDALDGGISCIVEELKFLSDPSNMKYSFTLASGTGLCCDNIRSVVNTIVVSYNIPISAQFNYLVKTIGEYITDDRDIL--SGLILVMVKRRRTAVELCKMMKTSPLVNE-KLSVVSITGHGGGGGDGMKVSSQRKVFQEIKEGKHQIIITTSVAEEGVDLPKCSLVITLNPPTSVITLVQMRGRARKNNSIFLVVCENTK 678
BLAST of Dicer-like protein 1 vs. TrEMBL
Match: A0A1I8H7V4 (Uncharacterized protein OS=Macrostomum lignano OX=282301 PE=4 SV=1) HSP 1 Score: 202.601 bits (514), Expect = 1.007e-49 Identity = 182/736 (24.73%), Postives = 306/736 (41.58%), Query Frame = 2
Query: 512 NETNKPSDISPD-----ILNLLKPHKEGN------------WITCLLCQTKMNTDEQYAMHCSGSKHTKKIRSFNLSDHFI----------LKEESYNE--EMID----CKICNIKIHRNNQDSHDKGKMHRDNL-FKSKTEDIISQTVRKTELSDGLKNLKL---LKLEPRKYQLEIYE---KANGKDCVIFLPTGTGKTFIAAMLMLKMLEENPFHRVAFLVDKVLLVMQQSKSFKGQFEDICLERF----------ESQEKTVTRKLKLISLANEIIDSDHKCSIRDHDVIIATADFFKNILNKQQIYWTDFSLVVLDEAHHCVKEHPYNKLLFEYHLYPQRVLLNKNELLSVXXXXXXXXXXXXXXXXWKIRRCKIIGLTASPSGELDFDKTYELLKALLHSLGDVGIV--TVTENIDELNEFTSLTNMESRIVSYGESEKDLRKLMTTNFVFLLKKFERRVNGIGNGLILSSDTSLTIEEI---NNLK-SQLSGLLVDVREI---QKSILNHILALVDIIEAIDNIGYTIAKKKFDEILENENETVWYDNNIF-------NFKTISKEFQLLHQEQENSSIINEIVKECKSLQDE------NRTILVLVEERRDAREYKNSLEKEKLNFEFQ-LIVXXXXXXXXXXXXXMSVGEQKKALDFIREKKSQIIIATSVVDEGIDLPQCDLVITVNPPTSVQALVQIRGRARKKDSRLLMLCRDQKTIDILHELM 2500
N PS +SP + PH+ + C +C + NT +Q H G H K++R ++ L+ SY ++ D C +C I++H NN +H G+ HR L + D R+ + + N + +L PR YQLE Y + CV LPTGTGKT +AA+ +L LE NP FLVDKVLLV+QQ+ + Q + + RF TVTR L + ++ ++ + D+++ TA F+ N L + L+ +DEAHHC HPY+ L ++LS+ +++ +++G TASP+G+ T E+L LL LG + + + +L EF+ + R+V E + + +L + G +SD +L + ++ L L+G+L +V E + + + L + E +G + + E ++ + + + + + QLL + Q ++ ++ ++L D+ R LV+V ER AR + L +F L + GMSV +Q++ L + ++ ++AT + EG+DLP+CDL++ +PP+ V ALVQ RGR R R L+ CR + L +L+
Sbjct: 1337 NAAASPSAVSPSAGSAALSGSAVPHQAAGQAQPLVESQANGMLRCTVCNVQCNTPDQMLNHKQGKNHLKRLRVSGITQPAAATDRAGPEPDLQAASYQPVVQLPDGYSLCNLCGIRLHGNNVAAHVAGRDHRRRLAVRCPAPD------RQAPACEFVANPRTDWPTQLRPRIYQLEAYRLCCRHGNALCV--LPTGTGKTMVAALAILAALEANPLRSAVFLVDKVLLVLQQAAFLRAQLAQVRMRRFFRPLPPPSSPALPTPTVTRSLAVAAVCGDLHSLPDDQPLAAADLVVTTAAFYANCLRTGALRLDQACLLAMDEAHHCDALHPYSLL--------------AGQVLSMP----------------ELKSPRLLGFTASPAGQASLPATQEMLVGLLDRLGGARLAWPSSPDAQAQLAEFSVRAGISGRLVPPLTEETAAVAALINHSALVLTALRKAAEASG-----ASDAALLVNQLLSNGGLDCPNLAGVLDEVAERTADSQPVRLLVEQLRRLSELRSALGLAVCGDSRQLVAELDDAALSSLLSRELLTEMRQSAEALVDALQLLREGQAATAGAGSVL---RALADDLRGTGGARLALVIVRERATARRLADLLASHSAFADFADLRPACLIGHGAAGDAGMSVAQQRRLLYSVARGEANALVATPIACEGLDLPRCDLLVLADPPSRVAALVQSRGRVRVDAGRCLVYCRSAEERQRLQDLL 2026
BLAST of Dicer-like protein 1 vs. Ensembl Cavefish
Match: ifih1 (interferon induced with helicase C domain 1 [Source:NCBI gene;Acc:103026821]) HSP 1 Score: 70.4774 bits (171), Expect = 5.907e-12 Identity = 60/203 (29.56%), Postives = 102/203 (50.25%), Query Frame = 2
Query: 812 NLFKSKTEDIIS---QTVRKTELSDGLKNLKLLKLEPRKYQLEIYEKA-NGKDCVIFLPTGTGKTFIAAMLMLKMLEE----NPFHRVAFLVDKVLLVMQQSKSFKGQFEDICLERFESQEKTVTRKLKLISLANEIIDSDHKCSIRDHDVIIATADFFKNILNKQQ------IYWTDFSLVVLDEAHHCVKEHPYNKLLFEY 1378
+L+K E++ + QT + S G K++ L R YQ+E+ A GK+ ++ LPTG+GKT +A + + LE +V LV+K+ LV Q ++ +F RF + +V R +S +++ S K + ++D+II TA +N L K + + + F+L+V+DE HH K YN ++ Y
Sbjct: 292 DLYKGSDEEMKTKEEQTAGSQDQSVGEKDIVL-----RDYQMEVARPALEGKNIIVCLPTGSGKTRVAVYITKRHLESRRRIGQPGKVVVLVNKIPLVEQH---YRAEFG-----RFLKHQYSVER----VSGDSQLKISFPKV-VENNDIIICTAQILENSLAKAKKGDEDGVKLSQFTLMVIDECHHTQKGEAYNHIMIRY 476 HSP 2 Score: 55.0694 bits (131), Expect = 3.016e-7 Identity = 25/63 (39.68%), Postives = 42/63 (66.67%), Query Frame = 2
Query: 2255 MSVGEQKKALDFIREKKSQIIIATSVVDEGIDLPQCDLVITVNPPTSVQALVQIRGRARKKDS 2443
M+ EQK L+ RE + ++IAT+V +EG+D+ +C++V+ T+ A++Q RGR R +DS
Sbjct: 754 MTSAEQKNVLNKFREGEINLLIATTVAEEGLDVAECNVVVRYCLVTNETAMIQARGRGRAEDS 816
BLAST of Dicer-like protein 1 vs. Ensembl Cavefish
Match: ifih1 (interferon induced with helicase C domain 1 [Source:NCBI gene;Acc:103026821]) HSP 1 Score: 70.4774 bits (171), Expect = 6.082e-12 Identity = 60/203 (29.56%), Postives = 102/203 (50.25%), Query Frame = 2
Query: 812 NLFKSKTEDIIS---QTVRKTELSDGLKNLKLLKLEPRKYQLEIYEKA-NGKDCVIFLPTGTGKTFIAAMLMLKMLEE----NPFHRVAFLVDKVLLVMQQSKSFKGQFEDICLERFESQEKTVTRKLKLISLANEIIDSDHKCSIRDHDVIIATADFFKNILNKQQ------IYWTDFSLVVLDEAHHCVKEHPYNKLLFEY 1378
+L+K E++ + QT + S G K++ L R YQ+E+ A GK+ ++ LPTG+GKT +A + + LE +V LV+K+ LV Q ++ +F RF + +V R +S +++ S K + ++D+II TA +N L K + + + F+L+V+DE HH K YN ++ Y
Sbjct: 292 DLYKGSDEEMKTKEEQTAGSQDQSVGEKDIVL-----RDYQMEVARPALEGKNIIVCLPTGSGKTRVAVYITKRHLESRRRIGQPGKVVVLVNKIPLVEQH---YRAEFG-----RFLKHQYSVER----VSGDSQLKISFPKV-VENNDIIICTAQILENSLAKAKKGDEDGVKLSQFTLMVIDECHHTQKGEAYNHIMIRY 476 HSP 2 Score: 55.4546 bits (132), Expect = 2.913e-7 Identity = 25/63 (39.68%), Postives = 42/63 (66.67%), Query Frame = 2
Query: 2255 MSVGEQKKALDFIREKKSQIIIATSVVDEGIDLPQCDLVITVNPPTSVQALVQIRGRARKKDS 2443
M+ EQK L+ RE + ++IAT+V +EG+D+ +C++V+ T+ A++Q RGR R +DS
Sbjct: 720 MTSAEQKNVLNKFREGEINLLIATTVAEEGLDVAECNVVVRYCLVTNETAMIQARGRGRAEDS 782
BLAST of Dicer-like protein 1 vs. Ensembl Cavefish
Match: dhx58 (DExH-box helicase 58 [Source:NCBI gene;Acc:103032392]) HSP 1 Score: 70.0922 bits (170), Expect = 6.241e-12 Identity = 50/162 (30.86%), Postives = 84/162 (51.85%), Query Frame = 2
Query: 914 RKYQLEIYEKA-NGKDCVIFLPTGTGKTFIAAMLMLKMLEENPFHRVAFLVDKVLLVMQQ-SKSFKGQFEDICLERFESQEKTVTRKLKLISLANEIIDSDHKCS-IRDHDVIIATADFFKNIL----NKQQIYWTDFSLVVLDEAHHCVKEHPYNKLLFEY 1378
R YQ E+ ++A G++ +I+LPTG GKT A + K LE +VA LV+KV LV Q K F+ + I +K++ ++ + + D +++ D++I TA +N L + + DF+L+++DE HH K+ YNK++ Y
Sbjct: 7 RLYQKEVVQRALQGENSIIWLPTGGGKTRAAVYVAKKHLETRRNAKVAVLVNKVHLVDQHYQKEFQPRLGHI---------------VKIMPISGDSREKDFFGRVVKESDLVICTAQILENALINTEEDKHVELKDFTLLIIDECHHTHKDAVYNKIMARY 153
BLAST of Dicer-like protein 1 vs. Ensembl Cavefish
Match: ENSAMXT00000016457.2 (DExD/H-box helicase 58 [Source:NCBI gene;Acc:103047126]) HSP 1 Score: 63.5438 bits (153), Expect = 7.642e-10 Identity = 67/267 (25.09%), Postives = 105/267 (39.33%), Query Frame = 2
Query: 914 RKYQLEIYEKA-NGKDCVIFLPTGTGKTFIAAMLMLKMLEENPFH-RVAFLVDKVLLVMQQSKSFKGQFEDICLERFESQEKTVTRKLKLISLANEIIDSDHKCSIRD----HDVIIATADFFKNILNKQQIYWTD-FSLVVLDEAHHCVKEHPYNKLLFEY---------HLYPQRVLLNKNELLSVXXXXXXXXXXXXXXXXWKIRRCKIIGLTASPSGELDFDKTYELLKALLHSLGDVG---IVTVTENIDELNEFTSLTNME 1657
R+YQ E+ E A +G++ +I PTG GKT +A + L++ P +V F+ KV + QQ K F F K + + D+D +R ++V++ T N L + + D F+L++LDE H+ +HPYN ++ Y H PQ ++G TAS G F E + H ++ I TVT+NIDEL + + E
Sbjct: 255 REYQKELAEAAFSGQNTIICAPTGCGKTIVALAICEHHLKKFPGKAKVVFMATKVEVYAQQYKLFIDHFS----------------KDPDVRVTGVCGDTDVGVCLRSVVDRNEVVVLTPQILVNALQNKDLPSLDVFTLLLLDECHNTTGKHPYNNIMSRYLDTKLTSSAHTLPQ-----------------------------------VVGFTAS-VGVGSFKNQQEAEMNICHLCANLDTRVIATVTKNIDELRSYVHIPEKE 469 HSP 2 Score: 60.8474 bits (146), Expect = 5.568e-9 Identity = 31/69 (44.93%), Postives = 43/69 (62.32%), Query Frame = 2
Query: 2255 MSVGEQKKALD-FIREKKSQIIIATSVVDEGIDLPQCDLVITVNPPTSVQALVQIRGRARKKDSRLLML 2458
M++ QK LD F +I+IATSV DEGID+PQC+LV+ +V +VQ+RGR R SR ++
Sbjct: 685 MTLTSQKGVLDSFKTSDHIKILIATSVADEGIDIPQCNLVLMYEYVGNVVKMVQVRGRGRAAGSRCFLI 753
BLAST of Dicer-like protein 1 vs. Ensembl Cavefish
Match: dicer1 (dicer 1, ribonuclease III [Source:NCBI gene;Acc:103033221]) HSP 1 Score: 63.1586 bits (152), Expect = 1.291e-9 Identity = 42/163 (25.77%), Postives = 75/163 (46.01%), Query Frame = 2
Query: 911 PRKYQLEIYEKANGKDCVIFLPTGTGKTFIAAMLMLKM---LEENPFHRVAFLVDKVLLVMQQSKSFK-------GQFEDICLERFESQEKTVTRKLKLISLANEIIDSDHKCSIRDHDVIIATADFFKNILNKQQIYWTDFSLVVLDEAHHCVKEHPYNKLL 1369
PRKYQ+E+ E A + ++ L TG+GKTFIA +L+ ++ + R FLV+ V+QQ+ + + G++ D C E + + I ++ V++ T F + L + + +L+V DE H + +HPY ++
Sbjct: 34 PRKYQVELLEAALEHNTIVCLNTGSGKTFIAVLLIKELSHQIRRGNGRRTVFLVNAASSVVQQASTVRTHSDLQVGEYTDSCTSWLEEKWRQ---------------------DIMENQVLVMTCHIFLHALRSGVLCLSTINLLVFDECHLAITDHPYRDIM 175 HSP 2 Score: 59.6918 bits (143), Expect = 1.656e-8 Identity = 27/70 (38.57%), Postives = 47/70 (67.14%), Query Frame = 2
Query: 2267 EQKKALDFIREKKSQIIIATSVVDEGIDLPQCDLVITVNPPTSVQALVQIRGRARKKDSRLLMLCRDQKT 2476
+Q++ L R ++ ++IATS+V+EG+D+P+C+LV+ + PT ++ VQ +GRAR S +ML + T
Sbjct: 485 KQEEVLRKFRAHETNLLIATSIVEEGVDIPKCNLVVRFDLPTEYRSYVQSKGRARAPVSNYIMLADSECT 554
BLAST of Dicer-like protein 1 vs. Ensembl Sea Lamprey
Match: dicer1 (dicer 1, ribonuclease type III [Source:NCBI gene;Acc:324724]) HSP 1 Score: 60.8474 bits (146), Expect = 1.127e-9 Identity = 28/77 (36.36%), Postives = 48/77 (62.34%), Query Frame = 2
Query: 2267 EQKKALDFIREKKSQIIIATSVVDEGIDLPQCDLVITVNPPTSVQALVQIRGRARKKDSRLLMLCRDQKTIDILHEL 2497
+Q++ L R ++ +++ATS V+EG+DLP+C+LV+ +PP ++ VQ +GRA+ S +ML Q+ EL
Sbjct: 42 KQEEVLRKFRAHETNLLVATSAVEEGVDLPKCNLVVRFDPPADYRSYVQSKGRAQAPVSNYVMLADAQRMPAFHREL 118
BLAST of Dicer-like protein 1 vs. Ensembl Sea Lamprey
Match: DDX58 (DExD/H-box helicase 58 [Source:HGNC Symbol;Acc:HGNC:19102]) HSP 1 Score: 55.0694 bits (131), Expect = 5.583e-8 Identity = 27/69 (39.13%), Postives = 48/69 (69.57%), Query Frame = 2
Query: 2255 MSVGEQKKALDFIREKK-SQIIIATSVVDEGIDLPQCDLVITVNPPTSVQALVQIRGRARKKDSRLLML 2458
M++ +Q A+D RE++ S ++IATSV DEG+D+ +C+LV+ + +V VQ RGR R ++S+ +++
Sbjct: 317 MTLNQQSGAVDEFREEQGSNLLIATSVADEGLDIQRCNLVLLYDYVGNVIKSVQTRGRGRAENSKCMLI 385
BLAST of Dicer-like protein 1 vs. Ensembl Nematostella
Match: EDO48835 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RIP7]) HSP 1 Score: 69.3218 bits (168), Expect = 1.112e-14 Identity = 28/52 (53.85%), Postives = 40/52 (76.92%), Query Frame = 2
Query: 1229 DHDVIIATADFFKNILNKQQIYWTDFSLVVLDEAHHCVKEHPYNKLLFEYHL 1384
DHDV++ TAD +KN +N + + D +L+VLDEAHHC KEHPYN ++ +Y+L
Sbjct: 12 DHDVLVVTADCYKNHINNGTLRFEDLALIVLDEAHHCNKEHPYNVIIRDYYL 63
BLAST of Dicer-like protein 1 vs. Ensembl Nematostella
Match: EDO39479 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SA09]) HSP 1 Score: 61.6178 bits (148), Expect = 6.024e-12 Identity = 29/71 (40.85%), Postives = 50/71 (70.42%), Query Frame = 2
Query: 2264 GEQKKALDFIREKKSQIIIATSVVDEGIDLPQCDLVITVNPPTSVQALVQIRGRA-RKKDSRLLMLCRDQK 2473
GEQ+ L R + +++I+TSV++EG+D+P C+LV+ + ++++LVQ RGRA R+ DS ++LC + K
Sbjct: 5 GEQEVILKSFRTGRIKLLISTSVLEEGLDVPVCNLVVRFDSTMNLKSLVQSRGRASRRSDSHFVVLCSNGK 75
BLAST of Dicer-like protein 1 vs. Ensembl Nematostella
Match: EDO32367 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SV86]) HSP 1 Score: 60.8474 bits (146), Expect = 1.779e-9 Identity = 42/154 (27.27%), Postives = 71/154 (46.10%), Query Frame = 2
Query: 914 RKYQLEIYEKANGKDCVIFLPTGTGKTFIAAMLMLKMLEENPFHRVAFLVDKVLLVMQQSKSFKGQFEDICLERFESQEKTVTRKLKLISLANEIIDSDHKCSIRDHDVIIATADFFKNILNKQQIYWTDFSLVVLDEAHHCVKEHPYNKLLFE 1375
R YQ I +KA ++ ++ LPTG GKTFIAA++M P +V F+ LV QQ + ++ + + + ++ E T + + + R V T +N L++ D L+V+DEAH + H Y +++ E
Sbjct: 86 RDYQFNIVQKALYQNIMVTLPTGLGKTFIAAVVMYNYYRWYPQGKVVFMAPTKPLVAQQ---IEACYKIMGIPQTDTAEMT-----------GNMAPTKRENLWRTKRVFFLTPQVLQNDLSRGSCAAADVVLLVVDEAHKALGNHSYCQVVRE 225
BLAST of Dicer-like protein 1 vs. Ensembl Nematostella
Match: EDO47177 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RMY2]) HSP 1 Score: 58.9214 bits (141), Expect = 7.742e-9 Identity = 53/163 (32.52%), Postives = 80/163 (49.08%), Query Frame = 2
Query: 905 LEPRKYQLEIYEKA-NGKDCVIFLPTGTGKTFIAAMLMLKMLEENPFHRVAFLVDKVLLVMQQSKSFKGQFEDICLERFESQEKTVTRKLKLISLANEIIDSDHKCSIRDHDVIIATAD----FFKNILNKQQIYWTDFSLVVLDEAHHCVKEHPYNKLLFEY 1378
L+ R YQ E+ EKA G + VI PT +GKT++A + L++ +V F+V V LV QQ++ FK +D + + S I L+ ++ S H V++ TA N L + + SL+V DE HH K+HPYNK++ Y
Sbjct: 1 LDLRGYQKELSEKALEGHNTVICAPTNSGKTYVALNIARNHLDKKKEGKVLFIVSTVNLVQQQTERFKLYLQDKYIVKDISGSNGCD-----IPLSG-LLGSSH--------VVVLTAQVMLCILVNALKDGSLQLSSVSLLVFDECHHTQKDHPYNKIMENY 149
BLAST of Dicer-like protein 1 vs. Ensembl Nematostella
Match: EDO44279 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RWA7]) HSP 1 Score: 57.7658 bits (138), Expect = 1.769e-8 Identity = 51/161 (31.68%), Postives = 76/161 (47.20%), Query Frame = 2
Query: 914 RKYQLEIYEKA-NGKDCVIFLPTGTGKTFIAAMLMLKMLEENPFH-RVAFLVDKVLLVMQQSKSFKGQFEDICLERFESQEKTVTRKLKLISLANEIIDSDHKCSIRDHDVIIATADFFKNIL-NKQQIYWTDFSLVV---LDEAHHCVKEHPYNKLLFEY 1378
RKYQ E+ E A G + VI PT +GKTF+A + + L+++ H +V F+V LV+QQ + F+ + + T LK + AN DV++ TA N L NK ++ S + DE HH K H YNK++ +Y
Sbjct: 4 RKYQEELAEPAIQGYNTVICAPTNSGKTFVAMEIAKQHLDKHSDHAKVIFIVSTQNLVLQQRQRFEAYLSNYAVCDISGVNSTEI-PLKFLLKAN--------------DVVVLTAQILLNALQNKNELSSISLSDLSLLIFDECHHTNKNHSYNKIMHQY 149
BLAST of Dicer-like protein 1 vs. Ensembl Medaka
Match: dhx58 (DExH-box helicase 58 [Source:NCBI gene;Acc:101162602]) HSP 1 Score: 68.9366 bits (167), Expect = 1.632e-11 Identity = 74/258 (28.68%), Postives = 112/258 (43.41%), Query Frame = 2
Query: 818 FKSKTEDIISQTVRKTELSDGLKNLK-------------LLKLEPRKYQLEIYEKA-NGKDCVIFLPTGTGKTFIAAMLMLKMLEENPFHRVAFLVDKVLLVMQQ-SKSFK---GQFEDICLERFESQEKTVTRKLKLISLANEIIDSDHKCSIRDHDVIIATADFFKNIL----NKQQIYWTDFSLVVLDEAHHCVKEHPYNKLLFEYHLYPQRVLLNKNELLSVXXXXXXXXXXXXXXXXWKIRRCKIIGLTASPS 1525
FK+ T D+ S+ R+ E + L LK + E KYQ E+ E+A G++ +I+LPTG GKT A + + LE +V LV+ V LV Q SK FK G ++ S+EK K+ ++ +DVII TA N L + + +D +L+++DE HH KE YNK++ Y ++ L + +L +I+GLTASP
Sbjct: 13 FKTPTADLSSRR-RRGEAAGVLLTLKAFSHVWHTLKESTMADFELYKYQEEVVERALKGENIIIWLPTGGGKTRAAVYVAKRHLETTANAKVVVLVNMVHLVDQHYSKEFKPHLGSLYNLIKVSGVSEEKDFFGKV-----------------VQRNDVIICTAQILYNALIDKEEAKHVELSDITLLIIDECHHTHKEAVYNKVM---RCYMEKKLKGERQL------------------------PQILGLTASPG 225
BLAST of Dicer-like protein 1 vs. Ensembl Medaka
Match: dicer1 (dicer 1, ribonuclease III [Source:NCBI gene;Acc:101164359]) HSP 1 Score: 68.1662 bits (165), Expect = 4.146e-11 Identity = 50/173 (28.90%), Postives = 82/173 (47.40%), Query Frame = 2
Query: 911 PRKYQLEIYEKANGKDCVIFLPTGTGKTFIAAMLMLKM-------LEENPFHRVAFLVDKVLLVMQQSKSFKGQFEDICLERFESQEKTVTRKLKLISLANEIIDSDHKCSIRDHDVIIATADFFKNILNKQQIYWTDFSLVVLDEAHHCVKEHPYNKL--LFEYHLYPQRVL 1402
PRKYQ+E+ E A + ++ L TG+GKTFIA +L ++ +EN R FL + +QQ+ + + + E + QE T + + I D+ V++ T F ++L + + +LVV D+ H + EHPY ++ LFE H R+L
Sbjct: 34 PRKYQVELLEAALEHNTIVCLNTGSGKTFIAVLLTKELSHQIRGSYQEN-ARRTVFLANATSSAVQQAAAVRTHSDLHVGEYSDPQEATTWSRQRWSR------------EIADNQVLVMTCHVFLHVLTNHILPLSKINLVVFDDCHLAITEHPYCEVMKLFEEHTCGSRIL 193 HSP 2 Score: 62.003 bits (149), Expect = 3.266e-9 Identity = 27/70 (38.57%), Postives = 48/70 (68.57%), Query Frame = 2
Query: 2267 EQKKALDFIREKKSQIIIATSVVDEGIDLPQCDLVITVNPPTSVQALVQIRGRARKKDSRLLMLCRDQKT 2476
+Q++ L R ++ ++IATS+V+EG+D+P+C+LV+ + PT ++ VQ +GRAR S +ML ++T
Sbjct: 490 KQEEVLRKFRAHETNLLIATSIVEEGVDIPKCNLVVRFDLPTEYRSYVQSKGRARAPVSNYIMLADSERT 559
BLAST of Dicer-like protein 1 vs. Ensembl Medaka
Match: ifih1 (interferon induced with helicase C domain 1 [Source:NCBI gene;Acc:101175445]) HSP 1 Score: 66.2402 bits (160), Expect = 1.082e-10 Identity = 49/164 (29.88%), Postives = 82/164 (50.00%), Query Frame = 2
Query: 920 YQLEIYEKA-NGKDCVIFLPTGTGKTFIAAMLMLKMLE----ENPFHRVAFLVDKVLLVMQQSKSFKGQFEDICLERFESQEKTVTRKLKLISLANEIIDSDHKCSIRDHDVIIATADFFKNILNK------QQIYWTDFSLVVLDEAHHCVKEHPYNKLLFEY 1378
YQ+E+ + A GK+ +I LPTG+GKT +A + + L+ E +V LV+KV LV Q + +F ++ + + +LK IS A ++ +D+II TA +N L + + + +D SL+++DE HH K YN ++ Y
Sbjct: 278 YQMEVAKPALEGKNIIICLPTGSGKTRVAVYITKEHLDLRRAEGKLGKVVVLVNKVPLVEQH---YTKEFTPYLKHSYKVERVSGDSQLK-ISFAK---------IVQRNDIIICTAQILENYLERATSGVDEGVKLSDLSLMIIDECHHTQKGEAYNHIMMRY 428 HSP 2 Score: 50.447 bits (119), Expect = 8.098e-6 Identity = 23/63 (36.51%), Postives = 38/63 (60.32%), Query Frame = 2
Query: 2255 MSVGEQKKALDFIREKKSQIIIATSVVDEGIDLPQCDLVITVNPPTSVQALVQIRGRARKKDS 2443
M+ EQK L + +++AT+V +EG+D+P C+ VI T+ A++Q +GR R +DS
Sbjct: 706 MTAAEQKDVLKKFSTGEVNLLVATTVAEEGLDIPACNFVIRYGHVTNEIAMIQSQGRGRAEDS 768
BLAST of Dicer-like protein 1 vs. Ensembl Medaka
Match: dhx58 (DExH-box helicase 58 [Source:NCBI gene;Acc:101162602]) HSP 1 Score: 65.855 bits (159), Expect = 1.379e-10 Identity = 64/216 (29.63%), Postives = 96/216 (44.44%), Query Frame = 2
Query: 905 LEPRKYQLEIYEKA-NGKDCVIFLPTGTGKTFIAAMLMLKMLEENPFHRVAFLVDKVLLVMQQ-SKSFK---GQFEDICLERFESQEKTVTRKLKLISLANEIIDSDHKCSIRDHDVIIATADFFKNIL----NKQQIYWTDFSLVVLDEAHHCVKEHPYNKLLFEYHLYPQRVLLNKNELLSVXXXXXXXXXXXXXXXXWKIRRCKIIGLTASPS 1525
E KYQ E+ E+A G++ +I+LPTG GKT A + + LE +V LV+ V LV Q SK FK G ++ S+EK K+ ++ +DVII TA N L + + +D +L+++DE HH KE YNK++ Y ++ L + +L +I+GLTASP
Sbjct: 4 FELYKYQEEVVERALKGENIIIWLPTGGGKTRAAVYVAKRHLETTANAKVVVLVNMVHLVDQHYSKEFKPHLGSLYNLIKVSGVSEEKDFFGKV-----------------VQRNDVIICTAQILYNALIDKEEAKHVELSDITLLIIDECHHTHKEAVYNKVM---RCYMEKKLKGERQL------------------------PQILGLTASPG 175
BLAST of Dicer-like protein 1 vs. Ensembl Medaka
Match: dicer1 (dicer 1, ribonuclease III [Source:NCBI gene;Acc:101164359]) HSP 1 Score: 64.6994 bits (156), Expect = 4.466e-10 Identity = 48/171 (28.07%), Postives = 81/171 (47.37%), Query Frame = 2
Query: 911 PRKYQLEIYEKANGKDCVIFLPTGTGKTFIAAMLMLKM-------LEENPFHRVAFLVDKVLLVMQQSKSFKGQFEDICLERFESQEKTVTRKLKLISLANEIIDSDHKCSIRDHDVIIATADFFKNILNKQQIYWTDFSLVVLDEAHHCVKEHPYNKLLFEYHLYPQRVL 1402
PRKYQ+E+ E A + ++ L TG+GKTFIA +L ++ +EN R FL + +QQ+ + + + E + QE T + + I D+ V++ T F ++L + + +LVV D+ H + EHPY +++ E H R+L
Sbjct: 34 PRKYQVELLEAALEHNTIVCLNTGSGKTFIAVLLTKELSHQIRGSYQEN-ARRTVFLANATSSAVQQAAAVRTHSDLHVGEYSDPQEATTWSRQRWSR------------EIADNQVLVMTCHVFLHVLTNHILPLSKINLVVFDDCHLAITEHPYCEVMKE-HTCGSRIL 190 HSP 2 Score: 62.003 bits (149), Expect = 2.584e-9 Identity = 27/70 (38.57%), Postives = 48/70 (68.57%), Query Frame = 2
Query: 2267 EQKKALDFIREKKSQIIIATSVVDEGIDLPQCDLVITVNPPTSVQALVQIRGRARKKDSRLLMLCRDQKT 2476
+Q++ L R ++ ++IATS+V+EG+D+P+C+LV+ + PT ++ VQ +GRAR S +ML ++T
Sbjct: 487 KQEEVLRKFRAHETNLLIATSIVEEGVDIPKCNLVVRFDLPTEYRSYVQSKGRARAPVSNYIMLADSERT 556
BLAST of Dicer-like protein 1 vs. Planmine SMEST
Match: SMESG000016950.1 (SMESG000016950.1) HSP 1 Score: 1542.32 bits (3992), Expect = 0.000e+0 Identity = 813/825 (98.55%), Postives = 819/825 (99.27%), Query Frame = 2
Query: 83 MDQCYSEKIFDDSAKKIVITCKLCNKKCDTDDQLNIHNKSKNHLKKLTAKQAEVNFVFSNGKSENISCPLHCKICGIDCNTLDQLESHNKGKLHLKKSMKNDFIHFKCDETPIQNQFSNEANLVRSSENIDIVKPYEVLSMNENETNKPSDISPDILNLLKPHKEGNWITCLLCQTKMNTDEQYAMHCSGSKHTKKIRSFNLSDHFILKEESYNEEMIDCKICNIKIHRNNQDSHDKGKMHRDNLFKSKTEDIISQTVRKTELSDGLKNLKLLKLEPRKYQLEIYEKANGKDCVIFLPTGTGKTFIAAMLMLKMLEENPFHRVAFLVDKVLLVMQQSKSFKGQFEDICLERFESQEKTVTRKLKLISLANEIIDSDHKCSIRDHDVIIATADFFKNILNKQQIYWTDFSLVVLDEAHHCVKEHPYNKLLFEYHLYPQRVLLNKNELLSVXXXXXXXXXXXXXXXXWKIRRCKIIGLTASPSGELDFDKTYELLKALLHSLGDVGIVTVTENIDELNEFTSLTNMESRIVSYGESEKDLRKLMTTNFVFLLKKFERRVNGIGNGLILSSDTSLTIEEINNLKSQLSGLLVDVREIQKSILNHILALVDIIEAIDNIGYTIAKKKFDEILENENETVWYDNNIFNFKTISKEFQLLHQEQENSSIINEIVKECKSLQDENRTILVLVEERRDAREYKNSLEKEKLNFEFQLIVXXXXXXXXXXXXXMSVGEQKKALDFIREKKSQIIIATSVVDEGIDLPQCDLVITVNPPTSVQALVQIRGRARKKDSRLLMLCRDQKTIDILHELMXXXXXXXXXXXXLISENNY 2557
MDQCYSEK+FDDSAKKIVITCKLCNKKCDTDDQLNIHNKSKNHLKK+TAKQAEVNFVFSNGKSENISCP HCKICGIDCNTLDQLESHNKGK HLKKS+KNDFI+FKCDETPIQNQFSNEANLVRSSENIDIVKPYEVLSMNENETNKPSDISPDILNLLKPHKEGNWI CLLCQTKMNTDEQYAMHCSGSKH KKIRSFNLSDHFILKEESYNEEMIDCKICNIKIHRNNQDSHDKGKMHRDNLFKSKTEDIISQTVRKTELSDGLKNLKLLKLEPRKYQLEIYEKANGKDCVIFLPTGTGKTFIAAMLMLKMLEENPFHRVAFLVDKVLLVMQQSKSFKGQFEDICLERFESQEKTVTRKLKLISLANE+IDSDHKCSIRDHDVIIATADFFKNILNKQQIYWTDFSLVVLDEAHHCVKEHPYNKLLFEYHLYPQ VLLNKNELLSVSDIQSPPEIISSELEEWKIRRCKIIGLTASPSGELDFDKTYELLKALLHSLGDVGIVTVTENIDELNEFTSLTNMESRIVSYGESEKDLRKLMTTNFVFLLKKFERRVNGIGNGLILSSDTSLTIEEINNLKSQLSGLLVDV+EIQKSILNHILALVDIIEAIDNIGYTIAKKKFDEILENENETVWYDNNIFNFKTISKEFQLLHQEQENSSIINEIVKECKSLQDENRTILVLVEERRDAREYKNSLEKEKLNFEFQLIVGHGGKGAKSKHKGMSVGEQKKALDFIREKKSQIIIATSVVDEGIDLPQCDLVITVNPP SVQALVQIRGRARKKDSRLLMLCRDQKTIDILHELMKKEENINKAIEKLISENNY
Sbjct: 1 MDQCYSEKVFDDSAKKIVITCKLCNKKCDTDDQLNIHNKSKNHLKKITAKQAEVNFVFSNGKSENISCPFHCKICGIDCNTLDQLESHNKGKSHLKKSIKNDFINFKCDETPIQNQFSNEANLVRSSENIDIVKPYEVLSMNENETNKPSDISPDILNLLKPHKEGNWIACLLCQTKMNTDEQYAMHCSGSKHKKKIRSFNLSDHFILKEESYNEEMIDCKICNIKIHRNNQDSHDKGKMHRDNLFKSKTEDIISQTVRKTELSDGLKNLKLLKLEPRKYQLEIYEKANGKDCVIFLPTGTGKTFIAAMLMLKMLEENPFHRVAFLVDKVLLVMQQSKSFKGQFEDICLERFESQEKTVTRKLKLISLANELIDSDHKCSIRDHDVIIATADFFKNILNKQQIYWTDFSLVVLDEAHHCVKEHPYNKLLFEYHLYPQHVLLNKNELLSVSDIQSPPEIISSELEEWKIRRCKIIGLTASPSGELDFDKTYELLKALLHSLGDVGIVTVTENIDELNEFTSLTNMESRIVSYGESEKDLRKLMTTNFVFLLKKFERRVNGIGNGLILSSDTSLTIEEINNLKSQLSGLLVDVQEIQKSILNHILALVDIIEAIDNIGYTIAKKKFDEILENENETVWYDNNIFNFKTISKEFQLLHQEQENSSIINEIVKECKSLQDENRTILVLVEERRDAREYKNSLEKEKLNFEFQLIVGHGGKGAKSKHKGMSVGEQKKALDFIREKKSQIIIATSVVDEGIDLPQCDLVITVNPPASVQALVQIRGRARKKDSRLLMLCRDQKTIDILHELMKKEENINKAIEKLISENNY 825
BLAST of Dicer-like protein 1 vs. Planmine SMEST
Match: SMESG000014858.1 (SMESG000014858.1) HSP 1 Score: 111.694 bits (278), Expect = 8.989e-25 Identity = 140/561 (24.96%), Postives = 246/561 (43.85%), Query Frame = 2
Query: 905 LEPRKYQLEIY-EKANGKDCVIFLPTGTGKTFIAAMLMLKMLEENPFHRVAFLVDKVLLVMQQSKSFKGQFEDICLERFESQEKTVTRKLKLISLANEIIDSDHKCSIRDHDVIIATADFFKNILNKQQ----IYWTDFSLVVLDEAHHCVKEHPYNKLLFEYHLYPQRVLLNKNELLSVXXXXXXXXXXXXXXXXWKIRRCK-----IIGLTASP----SGELDFDKTYELLKALLHSLGDVGIVTVTENIDELN-----------------------EFTSLTNMESRIVSYGESEKDLRKLMTTNFVFLLKKFERRVNGIGNGLILSSDTSL--TIEEINNLKSQLSGLLVDVREIQKSIL-NHILALVDIIEAIDNIGYTIAKKKFDEILENENETVWYDNNIFNFKTISKEFQLLHQEQENSS---IINEIVKECKSLQDENRTILVLVEERRDAREYKNSLEKEKLNFEFQLIVXXXXXXXXXXXXXMSVGEQKKALDFIREKKSQIIIATSVVDEGIDLPQCDLVITVNPPTSVQALVQIRGRARKKDSRLLML 2458
LE R YQ E+ E GK+ +I PTG+GKT +A ++ + L+ NP +VAFLV ++ LV QQ FK ++ D + R K+ + L H ++ D+ I T+D +N L + +FSL++ DE H+C K+HPYN+++ Y +K+++ K IIGLTAS +G + DK + L L +L + TV E +EL+ E L ++ R++ + K TT +F + E R++ G + +T L E N+ + + + + ++++ NH+ D ++ I ++ D LENEN I K + ++ EN S + +EI ++ K ++ I+V V ER + K+ +K + +++V G ++ G++ E ++ L R + ++++T+V +EG+D+ C+LVI T+ A+VQ RGRAR DS+ +++
Sbjct: 379 LEVRDYQSELAKEGIGGKNVLICSPTGSGKTIVAVKIVQEHLKINPNGKVAFLVHRIALVEQQYNQFK-KYIDCKITRLTGSSKSSSTPL-----------VGH---LKSFDLFILTSDILRNALEEDNETVLKSLNEFSLILFDECHNCDKKHPYNRIMNHY---------------------------------FKLKKAKEKVPQIIGLTASTGTNKAGTM--DKALKRLFTLCANLDTCIVSTVKEFKEELDSMQKKPVEEIKTPHLRQNDDFDTELQKLMHLCERMLHEMNNRDFFPKDPTTQAMFTIP--EDRLHHKYLGFVGKLNTELYNMTNEPNDGRKAIFAISSYLNAFVRALMVNHLFRAQDAVKLIKDL--------LD--LENENPLTCKVERILKSKLKAIYEYENREDSENPSLKCLQDEITEQLK--KNSQSRIIVFVRERNYTQILKSIFSSQKSLIKCEVVV---GNTISAEQGGLTQNELEEVLGRFRRGEINVLVSTTVAEEGLDIEHCNLVIRYGHVTNETAMVQSRGRARAADSKYVVI 872
BLAST of Dicer-like protein 1 vs. Planmine SMEST
Match: SMESG000014858.1 (SMESG000014858.1) HSP 1 Score: 111.694 bits (278), Expect = 9.040e-25 Identity = 143/561 (25.49%), Postives = 250/561 (44.56%), Query Frame = 2
Query: 905 LEPRKYQLEIY-EKANGKDCVIFLPTGTGKTFIAAMLMLKMLEENPFHRVAFLVDKVLLVMQQSKSFKGQFEDICLERFESQEKTVTRKLKLISLANEIIDSDHKCSIRDHDVIIATADFFKNILNKQQ----IYWTDFSLVVLDEAHHCVKEHPYNKLLFEYHLYPQRVLLNKNELLSVXXXXXXXXXXXXXXXXWKIRRCK-----IIGLTASP----SGELDFDKTYELLKALLHSLGDVGIVTVTENIDELN-----------------------EFTSLTNMESRIVSYGESEKDLRKLMTTNFVFLLKKFERRVNGIGNGLILSSDTSL--TIEEINNLKSQLSGLLVDVREIQKSIL-NHILALVDIIEAIDNIGYTIAKKKFDEILENENETVWYDNNIFNFKTISKEFQLLHQEQENSS---IINEIVKECKSLQDENRTILVLVEERRDAREYKNSLEKEKLNFEFQLIVXXXXXXXXXXXXXMSVGEQKKALDFIREKKSQIIIATSVVDEGIDLPQCDLVITVNPPTSVQALVQIRGRARKKDSRLLML 2458
LE R YQ E+ E GK+ +I PTG+GKT +A ++ + L+ NP +VAFLV ++ LV QQ FK ++ D + R K+ + L H ++ D+ I T+D +N L + +FSL++ DE H+C K+HPYN+++ Y +K+++ K IIGLTAS +G + DK + L L +L + TV E +EL+ E L ++ R++ + K TT +F + E R++ G + +T L E N+ + + + + ++++ NH+ D ++ I ++ D LENEN I KTI E++ ++ EN S + +EI ++ K ++ I+V V ER + K+ +K + +++V G ++ G++ E ++ L R + ++++T+V +EG+D+ C+LVI T+ A+VQ RGRAR DS+ +++
Sbjct: 562 LEVRDYQSELAKEGIGGKNVLICSPTGSGKTIVAVKIVQEHLKINPNGKVAFLVHRIALVEQQYNQFK-KYIDCKITRLTGSSKSSSTPL-----------VGH---LKSFDLFILTSDILRNALEEDNETVLKSLNEFSLILFDECHNCDKKHPYNRIMNHY---------------------------------FKLKKAKEKVPQIIGLTASTGTNKAGTM--DKALKRLFTLCANLDTCIVSTVKEFKEELDSMQKKPVEEIKTPHLRQNDDFDTELQKLMHLCERMLHEMNNRDFFPKDPTTQAMFTIP--EDRLHHKYLGFVGKLNTELYNMTNEPNDGRKAIFAISSYLNAFVRALMVNHLFRAQDAVKLIKDL--------LD--LENENPLTCKVERI--LKTIY-EYE-NREDSENPSLKCLQDEITEQLK--KNSQSRIIVFVRERNYTQILKSIFSSQKSLIKCEVVV---GNTISAEQGGLTQNELEEVLGRFRRGEINVLVSTTVAEEGLDIEHCNLVIRYGHVTNETAMVQSRGRARAADSKYVVI 1051
BLAST of Dicer-like protein 1 vs. Planmine SMEST
Match: SMESG000014858.1 (SMESG000014858.1) HSP 1 Score: 111.694 bits (278), Expect = 1.038e-24 Identity = 140/561 (24.96%), Postives = 246/561 (43.85%), Query Frame = 2
Query: 905 LEPRKYQLEIY-EKANGKDCVIFLPTGTGKTFIAAMLMLKMLEENPFHRVAFLVDKVLLVMQQSKSFKGQFEDICLERFESQEKTVTRKLKLISLANEIIDSDHKCSIRDHDVIIATADFFKNILNKQQ----IYWTDFSLVVLDEAHHCVKEHPYNKLLFEYHLYPQRVLLNKNELLSVXXXXXXXXXXXXXXXXWKIRRCK-----IIGLTASP----SGELDFDKTYELLKALLHSLGDVGIVTVTENIDELN-----------------------EFTSLTNMESRIVSYGESEKDLRKLMTTNFVFLLKKFERRVNGIGNGLILSSDTSL--TIEEINNLKSQLSGLLVDVREIQKSIL-NHILALVDIIEAIDNIGYTIAKKKFDEILENENETVWYDNNIFNFKTISKEFQLLHQEQENSS---IINEIVKECKSLQDENRTILVLVEERRDAREYKNSLEKEKLNFEFQLIVXXXXXXXXXXXXXMSVGEQKKALDFIREKKSQIIIATSVVDEGIDLPQCDLVITVNPPTSVQALVQIRGRARKKDSRLLML 2458
LE R YQ E+ E GK+ +I PTG+GKT +A ++ + L+ NP +VAFLV ++ LV QQ FK ++ D + R K+ + L H ++ D+ I T+D +N L + +FSL++ DE H+C K+HPYN+++ Y +K+++ K IIGLTAS +G + DK + L L +L + TV E +EL+ E L ++ R++ + K TT +F + E R++ G + +T L E N+ + + + + ++++ NH+ D ++ I ++ D LENEN I K + ++ EN S + +EI ++ K ++ I+V V ER + K+ +K + +++V G ++ G++ E ++ L R + ++++T+V +EG+D+ C+LVI T+ A+VQ RGRAR DS+ +++
Sbjct: 412 LEVRDYQSELAKEGIGGKNVLICSPTGSGKTIVAVKIVQEHLKINPNGKVAFLVHRIALVEQQYNQFK-KYIDCKITRLTGSSKSSSTPL-----------VGH---LKSFDLFILTSDILRNALEEDNETVLKSLNEFSLILFDECHNCDKKHPYNRIMNHY---------------------------------FKLKKAKEKVPQIIGLTASTGTNKAGTM--DKALKRLFTLCANLDTCIVSTVKEFKEELDSMQKKPVEEIKTPHLRQNDDFDTELQKLMHLCERMLHEMNNRDFFPKDPTTQAMFTIP--EDRLHHKYLGFVGKLNTELYNMTNEPNDGRKAIFAISSYLNAFVRALMVNHLFRAQDAVKLIKDL--------LD--LENENPLTCKVERILKSKLKAIYEYENREDSENPSLKCLQDEITEQLK--KNSQSRIIVFVRERNYTQILKSIFSSQKSLIKCEVVV---GNTISAEQGGLTQNELEEVLGRFRRGEINVLVSTTVAEEGLDIEHCNLVIRYGHVTNETAMVQSRGRARAADSKYVVI 905
BLAST of Dicer-like protein 1 vs. Planmine SMEST
Match: SMESG000014858.1 (SMESG000014858.1) HSP 1 Score: 111.694 bits (278), Expect = 1.103e-24 Identity = 140/561 (24.96%), Postives = 246/561 (43.85%), Query Frame = 2
Query: 905 LEPRKYQLEIY-EKANGKDCVIFLPTGTGKTFIAAMLMLKMLEENPFHRVAFLVDKVLLVMQQSKSFKGQFEDICLERFESQEKTVTRKLKLISLANEIIDSDHKCSIRDHDVIIATADFFKNILNKQQ----IYWTDFSLVVLDEAHHCVKEHPYNKLLFEYHLYPQRVLLNKNELLSVXXXXXXXXXXXXXXXXWKIRRCK-----IIGLTASP----SGELDFDKTYELLKALLHSLGDVGIVTVTENIDELN-----------------------EFTSLTNMESRIVSYGESEKDLRKLMTTNFVFLLKKFERRVNGIGNGLILSSDTSL--TIEEINNLKSQLSGLLVDVREIQKSIL-NHILALVDIIEAIDNIGYTIAKKKFDEILENENETVWYDNNIFNFKTISKEFQLLHQEQENSS---IINEIVKECKSLQDENRTILVLVEERRDAREYKNSLEKEKLNFEFQLIVXXXXXXXXXXXXXMSVGEQKKALDFIREKKSQIIIATSVVDEGIDLPQCDLVITVNPPTSVQALVQIRGRARKKDSRLLML 2458
LE R YQ E+ E GK+ +I PTG+GKT +A ++ + L+ NP +VAFLV ++ LV QQ FK ++ D + R K+ + L H ++ D+ I T+D +N L + +FSL++ DE H+C K+HPYN+++ Y +K+++ K IIGLTAS +G + DK + L L +L + TV E +EL+ E L ++ R++ + K TT +F + E R++ G + +T L E N+ + + + + ++++ NH+ D ++ I ++ D LENEN I K + ++ EN S + +EI ++ K ++ I+V V ER + K+ +K + +++V G ++ G++ E ++ L R + ++++T+V +EG+D+ C+LVI T+ A+VQ RGRAR DS+ +++
Sbjct: 562 LEVRDYQSELAKEGIGGKNVLICSPTGSGKTIVAVKIVQEHLKINPNGKVAFLVHRIALVEQQYNQFK-KYIDCKITRLTGSSKSSSTPL-----------VGH---LKSFDLFILTSDILRNALEEDNETVLKSLNEFSLILFDECHNCDKKHPYNRIMNHY---------------------------------FKLKKAKEKVPQIIGLTASTGTNKAGTM--DKALKRLFTLCANLDTCIVSTVKEFKEELDSMQKKPVEEIKTPHLRQNDDFDTELQKLMHLCERMLHEMNNRDFFPKDPTTQAMFTIP--EDRLHHKYLGFVGKLNTELYNMTNEPNDGRKAIFAISSYLNAFVRALMVNHLFRAQDAVKLIKDL--------LD--LENENPLTCKVERILKSKLKAIYEYENREDSENPSLKCLQDEITEQLK--KNSQSRIIVFVRERNYTQILKSIFSSQKSLIKCEVVV---GNTISAEQGGLTQNELEEVLGRFRRGEINVLVSTTVAEEGLDIEHCNLVIRYGHVTNETAMVQSRGRARAADSKYVVI 1055 The following BLAST results are available for this feature:
BLAST of Dicer-like protein 1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Dicer-like protein 1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Dicer-like protein 1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 3
BLAST of Dicer-like protein 1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Dicer-like protein 1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Dicer-like protein 1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Dicer-like protein 1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Dicer-like protein 1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Dicer-like protein 1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Dicer-like protein 1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 2
BLAST of Dicer-like protein 1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of Dicer-like protein 1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Dicer-like protein 1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Dicer-like protein 1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30009440 ID=SMED30009440|Name=Dicer-like protein 1|organism=Schmidtea mediterranea sexual|type=transcript|length=2586bpback to top protein sequence of SMED30009440-orf-1 >SMED30009440-orf-1 ID=SMED30009440-orf-1|Name=SMED30009440-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=826bp MDQCYSEKIFDDSAKKIVITCKLCNKKCDTDDQLNIHNKSKNHLKKLTAKback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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