SMED30009414

Overview
NameSMED30009414
Smed IDSMED30009414
Length (bp)2392
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of SMED30009414 (SMED30009414) t-SNE clustered cells

Violin plots show distribution of expression levels for SMED30009414 (SMED30009414) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of SMED30009414 (SMED30009414) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for SMED30009414 (SMED30009414) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020




SMED30009414

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 1

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
Category 4 cellSMED30009414h1SMcG0015703 dd_Smed_v4_17939_1_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017
whole organism asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
BLAST of SMED30009414 vs. Ensembl Human
Match: DIP2B (disco interacting protein 2 homolog B [Source:HGNC Symbol;Acc:HGNC:29284])

HSP 1 Score: 93.2041 bits (230), Expect = 1.157e-18
Identity = 51/108 (47.22%), Postives = 65/108 (60.19%), Query Frame = -1
Query: 1823 VSSRVSEKIQQLVQTLKRPKRRPLPEYFQEDENLAVLTTFEDPNAPKPKGTVIEPAIGESLNMLSGLPRSLESALQSYAQAHGKQSVMSCIDSNGRVNGISLTYTKLL 2146
            VSSRVS KIQQL+ TLKRPKR PL E+F +D    V     DPN PKP+G  + P  GE L ++   P +LESALQ +     K S ++ +D  G+    +LTY KL 
Sbjct:  269 VSSRVSTKIQQLLNTLKRPKRPPLKEFFVDDSEEIVEVPQPDPNQPKPEGRQMTPVKGEPLGVICNWPPALESALQRWGTTQAKCSCLTALDMTGK-PVYTLTYGKLW 375          
BLAST of SMED30009414 vs. Ensembl Human
Match: DIP2C (disco interacting protein 2 homolog C [Source:HGNC Symbol;Acc:HGNC:29150])

HSP 1 Score: 92.4337 bits (228), Expect = 2.292e-18
Identity = 66/176 (37.50%), Postives = 94/176 (53.41%), Query Frame = -1
Query: 1823 HGVPPDVTSHTPNALKDQNSVTTDSITSSIGDNIRRSRDDASCPSQTGSVNSLQTGGTNNGAVENGL-VSSRVSEKIQQLVQTLKRPKRRPLPEYFQEDENLAVLTTFEDPNAPKPKGTVIEPAIGESLNMLSGLPRSLESALQSYAQAHGKQSVMSCIDSNGRVNGISLTYTKLL 2347
            H  PPDVT++T      ++S+  +    S G          + P + G+   ++TG        +G+ VSSRVS KIQQLV TLKRPKR PL E+F +D    +     DPN PKP+G  +    GE L +++  P SLE+ALQ +     K   ++ +D+NG+   I LTY KL 
Sbjct:  185 HSAPPDVTTYT-----SEHSIQVERPQGSTGSR--------TAP-KYGNAELMETG--------DGVPVSSRVSAKIQQLVNTLKRPKRPPLREFFVDDFEELLEVQQPDPNQPKPEGAQMLAMRGEQLGVVTNWPPSLEAALQRWGTISPKAPCLTTMDTNGKPLYI-LTYGKLW 337          
BLAST of SMED30009414 vs. Ensembl Human
Match: DIP2C (disco interacting protein 2 homolog C [Source:HGNC Symbol;Acc:HGNC:29150])

HSP 1 Score: 92.4337 bits (228), Expect = 2.341e-18
Identity = 66/176 (37.50%), Postives = 94/176 (53.41%), Query Frame = -1
Query: 1823 HGVPPDVTSHTPNALKDQNSVTTDSITSSIGDNIRRSRDDASCPSQTGSVNSLQTGGTNNGAVENGL-VSSRVSEKIQQLVQTLKRPKRRPLPEYFQEDENLAVLTTFEDPNAPKPKGTVIEPAIGESLNMLSGLPRSLESALQSYAQAHGKQSVMSCIDSNGRVNGISLTYTKLL 2347
            H  PPDVT++T      ++S+  +    S G          + P + G+   ++TG        +G+ VSSRVS KIQQLV TLKRPKR PL E+F +D    +     DPN PKP+G  +    GE L +++  P SLE+ALQ +     K   ++ +D+NG+   I LTY KL 
Sbjct:  204 HSAPPDVTTYT-----SEHSIQVERPQGSTGSR--------TAP-KYGNAELMETG--------DGVPVSSRVSAKIQQLVNTLKRPKRPPLREFFVDDFEELLEVQQPDPNQPKPEGAQMLAMRGEQLGVVTNWPPSLEAALQRWGTISPKAPCLTTMDTNGKPLYI-LTYGKLW 356          
BLAST of SMED30009414 vs. Ensembl Human
Match: DIP2C (disco interacting protein 2 homolog C [Source:HGNC Symbol;Acc:HGNC:29150])

HSP 1 Score: 92.0485 bits (227), Expect = 2.539e-18
Identity = 66/176 (37.50%), Postives = 94/176 (53.41%), Query Frame = -1
Query: 1823 HGVPPDVTSHTPNALKDQNSVTTDSITSSIGDNIRRSRDDASCPSQTGSVNSLQTGGTNNGAVENGL-VSSRVSEKIQQLVQTLKRPKRRPLPEYFQEDENLAVLTTFEDPNAPKPKGTVIEPAIGESLNMLSGLPRSLESALQSYAQAHGKQSVMSCIDSNGRVNGISLTYTKLL 2347
            H  PPDVT++T      ++S+  +    S G          + P + G+   ++TG        +G+ VSSRVS KIQQLV TLKRPKR PL E+F +D    +     DPN PKP+G  +    GE L +++  P SLE+ALQ +     K   ++ +D+NG+   I LTY KL 
Sbjct:  260 HSAPPDVTTYT-----SEHSIQVERPQGSTGSR--------TAP-KYGNAELMETG--------DGVPVSSRVSAKIQQLVNTLKRPKRPPLREFFVDDFEELLEVQQPDPNQPKPEGAQMLAMRGEQLGVVTNWPPSLEAALQRWGTISPKAPCLTTMDTNGKPLYI-LTYGKLW 412          
BLAST of SMED30009414 vs. Ensembl Human
Match: DIP2A (disco interacting protein 2 homolog A [Source:HGNC Symbol;Acc:HGNC:17217])

HSP 1 Score: 78.5666 bits (192), Expect = 4.152e-14
Identity = 56/135 (41.48%), Postives = 75/135 (55.56%), Query Frame = -1
Query: 1823 QTGSVNSLQTG--GTNNGAVENGLVSSRVSEKIQQLVQTLKRPKRRPLPEYFQED-ENLAVLTTFEDPNAPKPKGTVIEPAIGESLNMLSGLPR--SLESALQSYAQAHGKQSVMSCIDSNGRVNGISLTYTKLL 2212
            Q  SV S+  G  G+     +   V+SRVS KIQQL+ TLKRPKR PL E+F +D E L      EDPN PKP+G+      GE L   +G+PR  SL + LQ +     K   ++ +D+ G+    +LTY KL 
Sbjct:  241 QVASVRSVPRGCSGSMLETADGVPVNSRVSSKIQQLLNTLKRPKRPPLKEFFVDDFEEL-----LEDPNQPKPEGSETSVLRGEPLT--AGVPRPPSLLATLQRWGTTQPKSPCLTALDTTGKAV-YTLTYGKLW 367          
BLAST of SMED30009414 vs. Ensembl Celegans
Match: dip-2 (Disco-Interacting Protein 2 homolog [Source:UniProtKB/TrEMBL;Acc:A0A061AE78])

HSP 1 Score: 73.559 bits (179), Expect = 5.004e-13
Identity = 39/111 (35.14%), Postives = 64/111 (57.66%), Query Frame = -1
Query: 1826 LVSSRVSEKIQQLVQTLKRPKRRPLPEYFQEDE-NLAVLTTFEDPNAPKPKGTVIEPAIGESL--NMLSGLPRSLESALQSYAQAHGKQSVMSCIDSNGRVNGISLTYTKL 2149
            L  ++VS KIQ +V  L+RP+ +PL +Y+ +D+  L  +    DP+AP+P+GT++ P  GE+   N  + +PRSL+SA   +     K      +D + + +   LTY KL
Sbjct:  335 LKQAKVSSKIQNVVNALQRPRSKPLQDYYNDDDAELEAMAKIRDPDAPRPEGTIMNPVRGEAAHSNTNNTMPRSLDSAFHRFGTTAAKNIAAMVLDQSAKPS-TQLTYGKL 444          
BLAST of SMED30009414 vs. Ensembl Celegans
Match: dip-2 (Disco-Interacting Protein 2 homolog [Source:UniProtKB/TrEMBL;Acc:A0A061AE78])

HSP 1 Score: 73.559 bits (179), Expect = 5.618e-13
Identity = 39/111 (35.14%), Postives = 64/111 (57.66%), Query Frame = -1
Query: 1826 LVSSRVSEKIQQLVQTLKRPKRRPLPEYFQEDE-NLAVLTTFEDPNAPKPKGTVIEPAIGESL--NMLSGLPRSLESALQSYAQAHGKQSVMSCIDSNGRVNGISLTYTKL 2149
            L  ++VS KIQ +V  L+RP+ +PL +Y+ +D+  L  +    DP+AP+P+GT++ P  GE+   N  + +PRSL+SA   +     K      +D + + +   LTY KL
Sbjct:  309 LKQAKVSSKIQNVVNALQRPRSKPLQDYYNDDDAELEAMAKIRDPDAPRPEGTIMNPVRGEAAHSNTNNTMPRSLDSAFHRFGTTAAKNIAAMVLDQSAKPS-TQLTYGKL 418          
BLAST of SMED30009414 vs. Ensembl Celegans
Match: dip-2 (Disco-Interacting Protein 2 homolog [Source:UniProtKB/TrEMBL;Acc:A0A061AE78])

HSP 1 Score: 68.5514 bits (166), Expect = 1.692e-11
Identity = 39/113 (34.51%), Postives = 64/113 (56.64%), Query Frame = -1
Query: 1826 LVSSRVSEKIQQLVQTLKRPKRRPLPEYFQEDE-NLAVLTTFEDPNAPKPKGTVIEPAIGESL--NMLSGLPRSLE--SALQSYAQAHGKQSVMSCIDSNGRVNGISLTYTKL 2149
            L  ++VS KIQ +V  L+RP+ +PL +Y+ +D+  L  +    DP+AP+P+GT++ P  GE+   N  + +PRSL+  SA   +     K      +D + + +   LTY KL
Sbjct:  335 LKQAKVSSKIQNVVNALQRPRSKPLQDYYNDDDAELEAMAKIRDPDAPRPEGTIMNPVRGEAAHSNTNNTMPRSLDSFSAFHRFGTTAAKNIAAMVLDQSAKPS-TQLTYGKL 446          
BLAST of SMED30009414 vs. Ensembl Celegans
Match: dip-2 (Disco-Interacting Protein 2 homolog [Source:UniProtKB/TrEMBL;Acc:A0A061AE78])

HSP 1 Score: 68.1662 bits (165), Expect = 2.016e-11
Identity = 39/113 (34.51%), Postives = 64/113 (56.64%), Query Frame = -1
Query: 1826 LVSSRVSEKIQQLVQTLKRPKRRPLPEYFQEDE-NLAVLTTFEDPNAPKPKGTVIEPAIGESL--NMLSGLPRSLE--SALQSYAQAHGKQSVMSCIDSNGRVNGISLTYTKL 2149
            L  ++VS KIQ +V  L+RP+ +PL +Y+ +D+  L  +    DP+AP+P+GT++ P  GE+   N  + +PRSL+  SA   +     K      +D + + +   LTY KL
Sbjct:  309 LKQAKVSSKIQNVVNALQRPRSKPLQDYYNDDDAELEAMAKIRDPDAPRPEGTIMNPVRGEAAHSNTNNTMPRSLDSFSAFHRFGTTAAKNIAAMVLDQSAKPS-TQLTYGKL 420          
BLAST of SMED30009414 vs. Ensembl Celegans
Match: dip-2 (Disco-Interacting Protein 2 homolog [Source:UniProtKB/TrEMBL;Acc:A0A061AE78])

HSP 1 Score: 60.8474 bits (146), Expect = 4.096e-9
Identity = 34/109 (31.19%), Postives = 59/109 (54.13%), Query Frame = -1
Query: 1826 KIQQLVQTLK------RPKRRPLPEYFQEDE-NLAVLTTFEDPNAPKPKGTVIEPAIGESL--NMLSGLPRSLESALQSYAQAHGKQSVMSCIDSNGRVNGISLTYTKL 2125
            K+ Q +Q ++      RP+ +PL +Y+ +D+  L  +    DP+AP+P+GT++ P  GE+   N  + +PRSL+SA   +     K      +D + + +   LTY KL
Sbjct:  197 KLNQTIQAIEENRQKLRPRSKPLQDYYNDDDAELEAMAKIRDPDAPRPEGTIMNPVRGEAAHSNTNNTMPRSLDSAFHRFGTTAAKNIAAMVLDQSAKPS-TQLTYGKL 304          
BLAST of SMED30009414 vs. Ensembl Fly
Match: DIP2 (gene:FBgn0024806 transcript:FBtr0332110)

HSP 1 Score: 107.071 bits (266), Expect = 2.754e-23
Identity = 54/106 (50.94%), Postives = 74/106 (69.81%), Query Frame = -1
Query: 1823 RVSEKIQQLVQTLKRPKRRPLPEYFQE-DENLAVLTTFEDPNAPKPKGTVIEPAIGESLNMLSGLPRSLESALQSYAQAHGKQSVMSCIDSNGRVNGISLTYTKLL 2137
            +VS KIQQL+ TLKRPKRRPLPE++++ D  L +    +DPNAPKP+G+ + P  GE L++ +GLPR+LE ALQ Y     K  + + +D NG+V   +LTY KLL
Sbjct:  381 KVSAKIQQLLNTLKRPKRRPLPEFYEDNDIELEIAANTKDPNAPKPEGSTMTPVQGEQLSIPAGLPRTLECALQRYGTNSFKSPMATVLDPNGKVT-TTLTYGKLL 485          
BLAST of SMED30009414 vs. Ensembl Fly
Match: DIP2 (gene:FBgn0024806 transcript:FBtr0332109)

HSP 1 Score: 107.071 bits (266), Expect = 3.135e-23
Identity = 54/106 (50.94%), Postives = 74/106 (69.81%), Query Frame = -1
Query: 1823 RVSEKIQQLVQTLKRPKRRPLPEYFQE-DENLAVLTTFEDPNAPKPKGTVIEPAIGESLNMLSGLPRSLESALQSYAQAHGKQSVMSCIDSNGRVNGISLTYTKLL 2137
            +VS KIQQL+ TLKRPKRRPLPE++++ D  L +    +DPNAPKP+G+ + P  GE L++ +GLPR+LE ALQ Y     K  + + +D NG+V   +LTY KLL
Sbjct:  380 KVSAKIQQLLNTLKRPKRRPLPEFYEDNDIELEIAANTKDPNAPKPEGSTMTPVQGEQLSIPAGLPRTLECALQRYGTNSFKSPMATVLDPNGKVT-TTLTYGKLL 484          
BLAST of SMED30009414 vs. Ensembl Fly
Match: DIP2 (gene:FBgn0024806 transcript:FBtr0332108)

HSP 1 Score: 107.071 bits (266), Expect = 3.234e-23
Identity = 54/106 (50.94%), Postives = 74/106 (69.81%), Query Frame = -1
Query: 1823 RVSEKIQQLVQTLKRPKRRPLPEYFQE-DENLAVLTTFEDPNAPKPKGTVIEPAIGESLNMLSGLPRSLESALQSYAQAHGKQSVMSCIDSNGRVNGISLTYTKLL 2137
            +VS KIQQL+ TLKRPKRRPLPE++++ D  L +    +DPNAPKP+G+ + P  GE L++ +GLPR+LE ALQ Y     K  + + +D NG+V   +LTY KLL
Sbjct:  381 KVSAKIQQLLNTLKRPKRRPLPEFYEDNDIELEIAANTKDPNAPKPEGSTMTPVQGEQLSIPAGLPRTLECALQRYGTNSFKSPMATVLDPNGKVT-TTLTYGKLL 485          
BLAST of SMED30009414 vs. Ensembl Fly
Match: DIP2 (gene:FBgn0024806 transcript:FBtr0072520)

HSP 1 Score: 107.071 bits (266), Expect = 3.245e-23
Identity = 54/106 (50.94%), Postives = 74/106 (69.81%), Query Frame = -1
Query: 1823 RVSEKIQQLVQTLKRPKRRPLPEYFQE-DENLAVLTTFEDPNAPKPKGTVIEPAIGESLNMLSGLPRSLESALQSYAQAHGKQSVMSCIDSNGRVNGISLTYTKLL 2137
            +VS KIQQL+ TLKRPKRRPLPE++++ D  L +    +DPNAPKP+G+ + P  GE L++ +GLPR+LE ALQ Y     K  + + +D NG+V   +LTY KLL
Sbjct:  381 KVSAKIQQLLNTLKRPKRRPLPEFYEDNDIELEIAANTKDPNAPKPEGSTMTPVQGEQLSIPAGLPRTLECALQRYGTNSFKSPMATVLDPNGKVT-TTLTYGKLL 485          
BLAST of SMED30009414 vs. Ensembl Fly
Match: DIP2 (gene:FBgn0024806 transcript:FBtr0305325)

HSP 1 Score: 107.071 bits (266), Expect = 3.404e-23
Identity = 54/106 (50.94%), Postives = 74/106 (69.81%), Query Frame = -1
Query: 1823 RVSEKIQQLVQTLKRPKRRPLPEYFQE-DENLAVLTTFEDPNAPKPKGTVIEPAIGESLNMLSGLPRSLESALQSYAQAHGKQSVMSCIDSNGRVNGISLTYTKLL 2137
            +VS KIQQL+ TLKRPKRRPLPE++++ D  L +    +DPNAPKP+G+ + P  GE L++ +GLPR+LE ALQ Y     K  + + +D NG+V   +LTY KLL
Sbjct:  380 KVSAKIQQLLNTLKRPKRRPLPEFYEDNDIELEIAANTKDPNAPKPEGSTMTPVQGEQLSIPAGLPRTLECALQRYGTNSFKSPMATVLDPNGKVT-TTLTYGKLL 484          
BLAST of SMED30009414 vs. Ensembl Zebrafish
Match: dip2ba (disco-interacting protein 2 homolog Bb [Source:NCBI gene;Acc:568954])

HSP 1 Score: 90.8929 bits (224), Expect = 4.347e-18
Identity = 48/108 (44.44%), Postives = 66/108 (61.11%), Query Frame = -1
Query: 1823 VSSRVSEKIQQLVQTLKRPKRRPLPEYFQEDENLAVLTTFEDPNAPKPKGTVIEPAIGESLNMLSGLPRSLESALQSYAQAHGKQSVMSCIDSNGRVNGISLTYTKLL 2146
            VSSRVS KIQQL+ TLKRPKR PL E+F +D+   V     DPN P+P+G  I P  GE L ++S  P +L++AL  +    GK   ++ +D  G+    +LT+ KL 
Sbjct:  239 VSSRVSTKIQQLLNTLKRPKRPPLSEFFMDDQEEIVEVPRADPNTPRPEGRQIIPVKGEPLGVVSNWPPALQAALARWGATQGKSPALTALDITGK-PLYTLTFGKLW 345          
BLAST of SMED30009414 vs. Ensembl Zebrafish
Match: dip2ba (disco-interacting protein 2 homolog Bb [Source:NCBI gene;Acc:568954])

HSP 1 Score: 90.8929 bits (224), Expect = 4.384e-18
Identity = 48/108 (44.44%), Postives = 66/108 (61.11%), Query Frame = -1
Query: 1823 VSSRVSEKIQQLVQTLKRPKRRPLPEYFQEDENLAVLTTFEDPNAPKPKGTVIEPAIGESLNMLSGLPRSLESALQSYAQAHGKQSVMSCIDSNGRVNGISLTYTKLL 2146
            VSSRVS KIQQL+ TLKRPKR PL E+F +D+   V     DPN P+P+G  I P  GE L ++S  P +L++AL  +    GK   ++ +D  G+    +LT+ KL 
Sbjct:  239 VSSRVSTKIQQLLNTLKRPKRPPLSEFFMDDQEEIVEVPRADPNTPRPEGRQIIPVKGEPLGVVSNWPPALQAALARWGATQGKSPALTALDITGK-PLYTLTFGKLW 345          
BLAST of SMED30009414 vs. Ensembl Zebrafish
Match: dip2bb (disco-interacting protein 2 homolog Bb [Source:ZFIN;Acc:ZDB-GENE-100729-4])

HSP 1 Score: 90.8929 bits (224), Expect = 4.384e-18
Identity = 48/108 (44.44%), Postives = 66/108 (61.11%), Query Frame = -1
Query: 1823 VSSRVSEKIQQLVQTLKRPKRRPLPEYFQEDENLAVLTTFEDPNAPKPKGTVIEPAIGESLNMLSGLPRSLESALQSYAQAHGKQSVMSCIDSNGRVNGISLTYTKLL 2146
            VSSRVS KIQQL+ TLKRPKR PL E+F +D+   V     DPN P+P+G  I P  GE L ++S  P +L++AL  +    GK   ++ +D  G+    +LT+ KL 
Sbjct:  239 VSSRVSTKIQQLLNTLKRPKRPPLSEFFMDDQEEIVEVPRADPNTPRPEGRQIIPVKGEPLGVVSNWPPALQAALARWGATQGKSPALTALDITGK-PLYTLTFGKLW 345          
BLAST of SMED30009414 vs. Ensembl Zebrafish
Match: dip2ca (disco-interacting protein 2 homolog Ca [Source:ZFIN;Acc:ZDB-GENE-031118-39])

HSP 1 Score: 90.1225 bits (222), Expect = 7.274e-18
Identity = 51/117 (43.59%), Postives = 71/117 (60.68%), Query Frame = -1
Query: 1823 NNGAVENGLVSSRVSEKIQQLVQTLKRPKRRPLPEYFQEDENLAVLTTFEDPNAPKPKGTVIEPAIGESLNMLSGLPRSLESALQSYAQAHGKQSVMSCIDSNGRVNGISLTYTKLL 2173
            N   +E G VSSRVS KIQQLV TLK+P+R PL E+F +D    +     DPN P+P+G  + P  GE L +++  P SLE+ALQ +     K   ++ +D+NG+   + LTY KL 
Sbjct:  248 NAELMETGDVSSRVSAKIQQLVNTLKQPRRPPLREFFVDDFEELLEVQQPDPNQPRPEGAQMVPIRGEPLGVVTNWPPSLEAALQRWGTISPKAPCLTTMDTNGKPLYV-LTYGKLW 363          
BLAST of SMED30009414 vs. Ensembl Zebrafish
Match: dip2ba (disco-interacting protein 2 homolog Bb [Source:NCBI gene;Acc:568954])

HSP 1 Score: 90.1225 bits (222), Expect = 7.547e-18
Identity = 48/108 (44.44%), Postives = 66/108 (61.11%), Query Frame = -1
Query: 1823 VSSRVSEKIQQLVQTLKRPKRRPLPEYFQEDENLAVLTTFEDPNAPKPKGTVIEPAIGESLNMLSGLPRSLESALQSYAQAHGKQSVMSCIDSNGRVNGISLTYTKLL 2146
            VSSRVS KIQQL+ TLKRPKR PL E+F +D+   V     DPN P+P+G  I P  GE L ++S  P +L++AL  +    GK   ++ +D  G+    +LT+ KL 
Sbjct:  289 VSSRVSTKIQQLLNTLKRPKRPPLSEFFMDDQEEIVEVPRADPNTPRPEGRQIIPVKGEPLGVVSNWPPALQAALARWGATQGKSPALTALDITGK-PLYTLTFGKLW 395          
BLAST of SMED30009414 vs. Ensembl Xenopus
Match: anxa5 (annexin A5 [Source:Xenbase;Acc:XB-GENE-1007295])

HSP 1 Score: 90.8929 bits (224), Expect = 6.236e-18
Identity = 49/108 (45.37%), Postives = 65/108 (60.19%), Query Frame = -1
Query: 1823 VSSRVSEKIQQLVQTLKRPKRRPLPEYFQEDENLAVLTTFEDPNAPKPKGTVIEPAIGESLNMLSGLPRSLESALQSYAQAHGKQSVMSCIDSNGRVNGISLTYTKLL 2146
            V+SRVS KIQQL+ TLKRPKR PL E+F +D    V     DPN PKP+G  + P  GE L ++   P S+E+ALQ +     K S ++ +D  G+    +LTY KL 
Sbjct:  258 VNSRVSTKIQQLLNTLKRPKRPPLKEFFVDDFEEIVEVPRPDPNQPKPEGRQVTPVKGEPLGVVCNWPPSVEAALQRWGTTQAKCSCLTALDVTGKPT-YTLTYGKLW 364          
BLAST of SMED30009414 vs. Ensembl Xenopus
Match: anxa5 (annexin A5 [Source:Xenbase;Acc:XB-GENE-1007295])

HSP 1 Score: 90.8929 bits (224), Expect = 6.412e-18
Identity = 49/108 (45.37%), Postives = 65/108 (60.19%), Query Frame = -1
Query: 1823 VSSRVSEKIQQLVQTLKRPKRRPLPEYFQEDENLAVLTTFEDPNAPKPKGTVIEPAIGESLNMLSGLPRSLESALQSYAQAHGKQSVMSCIDSNGRVNGISLTYTKLL 2146
            V+SRVS KIQQL+ TLKRPKR PL E+F +D    V     DPN PKP+G  + P  GE L ++   P S+E+ALQ +     K S ++ +D  G+    +LTY KL 
Sbjct:  272 VNSRVSTKIQQLLNTLKRPKRPPLKEFFVDDFEEIVEVPRPDPNQPKPEGRQVTPVKGEPLGVVCNWPPSVEAALQRWGTTQAKCSCLTALDVTGKPT-YTLTYGKLW 378          
BLAST of SMED30009414 vs. Ensembl Xenopus
Match: anxa5 (annexin A5 [Source:Xenbase;Acc:XB-GENE-1007295])

HSP 1 Score: 90.5077 bits (223), Expect = 6.500e-18
Identity = 49/108 (45.37%), Postives = 65/108 (60.19%), Query Frame = -1
Query: 1823 VSSRVSEKIQQLVQTLKRPKRRPLPEYFQEDENLAVLTTFEDPNAPKPKGTVIEPAIGESLNMLSGLPRSLESALQSYAQAHGKQSVMSCIDSNGRVNGISLTYTKLL 2146
            V+SRVS KIQQL+ TLKRPKR PL E+F +D    V     DPN PKP+G  + P  GE L ++   P S+E+ALQ +     K S ++ +D  G+    +LTY KL 
Sbjct:  253 VNSRVSTKIQQLLNTLKRPKRPPLKEFFVDDFEEIVEVPRPDPNQPKPEGRQVTPVKGEPLGVVCNWPPSVEAALQRWGTTQAKCSCLTALDVTGKPT-YTLTYGKLW 359          
BLAST of SMED30009414 vs. Ensembl Xenopus
Match: anxa5 (annexin A5 [Source:Xenbase;Acc:XB-GENE-1007295])

HSP 1 Score: 90.5077 bits (223), Expect = 6.778e-18
Identity = 49/108 (45.37%), Postives = 65/108 (60.19%), Query Frame = -1
Query: 1823 VSSRVSEKIQQLVQTLKRPKRRPLPEYFQEDENLAVLTTFEDPNAPKPKGTVIEPAIGESLNMLSGLPRSLESALQSYAQAHGKQSVMSCIDSNGRVNGISLTYTKLL 2146
            V+SRVS KIQQL+ TLKRPKR PL E+F +D    V     DPN PKP+G  + P  GE L ++   P S+E+ALQ +     K S ++ +D  G+    +LTY KL 
Sbjct:  292 VNSRVSTKIQQLLNTLKRPKRPPLKEFFVDDFEEIVEVPRPDPNQPKPEGRQVTPVKGEPLGVVCNWPPSVEAALQRWGTTQAKCSCLTALDVTGKPT-YTLTYGKLW 398          
BLAST of SMED30009414 vs. Ensembl Xenopus
Match: anxa5 (annexin A5 [Source:Xenbase;Acc:XB-GENE-1007295])

HSP 1 Score: 90.1225 bits (222), Expect = 8.513e-18
Identity = 49/108 (45.37%), Postives = 65/108 (60.19%), Query Frame = -1
Query: 1823 VSSRVSEKIQQLVQTLKRPKRRPLPEYFQEDENLAVLTTFEDPNAPKPKGTVIEPAIGESLNMLSGLPRSLESALQSYAQAHGKQSVMSCIDSNGRVNGISLTYTKLL 2146
            V+SRVS KIQQL+ TLKRPKR PL E+F +D    V     DPN PKP+G  + P  GE L ++   P S+E+ALQ +     K S ++ +D  G+    +LTY KL 
Sbjct:  281 VNSRVSTKIQQLLNTLKRPKRPPLKEFFVDDFEEIVEVPRPDPNQPKPEGRQVTPVKGEPLGVVCNWPPSVEAALQRWGTTQAKCSCLTALDVTGKPT-YTLTYGKLW 387          
BLAST of SMED30009414 vs. Ensembl Mouse
Match: Dip2c (disco interacting protein 2 homolog C [Source:MGI Symbol;Acc:MGI:1920179])

HSP 1 Score: 90.8929 bits (224), Expect = 3.807e-18
Identity = 67/180 (37.22%), Postives = 92/180 (51.11%), Query Frame = -1
Query: 1823 HGVPPDVTSHTPNALKDQNSVTTDSITSSIGDNIRRSRDDASCPSQT----GSVNSLQTGGTNNGAVENGL-VSSRVSEKIQQLVQTLKRPKRRPLPEYFQEDENLAVLTTFEDPNAPKPKGTVIEPAIGESLNMLSGLPRSLESALQSYAQAHGKQSVMSCIDSNGRVNGISLTYTKLL 2347
            H  PPDVT++T                     +I+  R   S  S+T    G+   ++TG        +G+ VSSRVS KIQQLV TLKRPKR PL E+F +D    +     DPN PKP+G  +    GE L +++  P SLE+ALQ +     K   ++ +D+NG+   I LTY KL 
Sbjct:  204 HSAPPDVTTYTSE------------------HSIQVERPQGSTTSRTAPKYGNAELMETG--------DGVPVSSRVSAKIQQLVNTLKRPKRPPLREFFVDDFEELLEVQQPDPNQPKPEGAQMLATRGEQLGVVTNWPPSLEAALQRWGTISPKAPCLTTMDTNGKPLYI-LTYGKLW 356          
BLAST of SMED30009414 vs. Ensembl Mouse
Match: Dip2c (disco interacting protein 2 homolog C [Source:MGI Symbol;Acc:MGI:1920179])

HSP 1 Score: 90.8929 bits (224), Expect = 4.301e-18
Identity = 67/180 (37.22%), Postives = 92/180 (51.11%), Query Frame = -1
Query: 1823 HGVPPDVTSHTPNALKDQNSVTTDSITSSIGDNIRRSRDDASCPSQT----GSVNSLQTGGTNNGAVENGL-VSSRVSEKIQQLVQTLKRPKRRPLPEYFQEDENLAVLTTFEDPNAPKPKGTVIEPAIGESLNMLSGLPRSLESALQSYAQAHGKQSVMSCIDSNGRVNGISLTYTKLL 2347
            H  PPDVT++T                     +I+  R   S  S+T    G+   ++TG        +G+ VSSRVS KIQQLV TLKRPKR PL E+F +D    +     DPN PKP+G  +    GE L +++  P SLE+ALQ +     K   ++ +D+NG+   I LTY KL 
Sbjct:  260 HSAPPDVTTYTSE------------------HSIQVERPQGSTTSRTAPKYGNAELMETG--------DGVPVSSRVSAKIQQLVNTLKRPKRPPLREFFVDDFEELLEVQQPDPNQPKPEGAQMLATRGEQLGVVTNWPPSLEAALQRWGTISPKAPCLTTMDTNGKPLYI-LTYGKLW 412          
BLAST of SMED30009414 vs. Ensembl Mouse
Match: Dip2c (disco interacting protein 2 homolog C [Source:MGI Symbol;Acc:MGI:1920179])

HSP 1 Score: 90.8929 bits (224), Expect = 4.328e-18
Identity = 67/180 (37.22%), Postives = 92/180 (51.11%), Query Frame = -1
Query: 1823 HGVPPDVTSHTPNALKDQNSVTTDSITSSIGDNIRRSRDDASCPSQT----GSVNSLQTGGTNNGAVENGL-VSSRVSEKIQQLVQTLKRPKRRPLPEYFQEDENLAVLTTFEDPNAPKPKGTVIEPAIGESLNMLSGLPRSLESALQSYAQAHGKQSVMSCIDSNGRVNGISLTYTKLL 2347
            H  PPDVT++T                     +I+  R   S  S+T    G+   ++TG        +G+ VSSRVS KIQQLV TLKRPKR PL E+F +D    +     DPN PKP+G  +    GE L +++  P SLE+ALQ +     K   ++ +D+NG+   I LTY KL 
Sbjct:  204 HSAPPDVTTYTSE------------------HSIQVERPQGSTTSRTAPKYGNAELMETG--------DGVPVSSRVSAKIQQLVNTLKRPKRPPLREFFVDDFEELLEVQQPDPNQPKPEGAQMLATRGEQLGVVTNWPPSLEAALQRWGTISPKAPCLTTMDTNGKPLYI-LTYGKLW 356          
BLAST of SMED30009414 vs. Ensembl Mouse
Match: Dip2b (disco interacting protein 2 homolog B [Source:MGI Symbol;Acc:MGI:2145977])

HSP 1 Score: 88.5817 bits (218), Expect = 1.895e-17
Identity = 49/108 (45.37%), Postives = 64/108 (59.26%), Query Frame = -1
Query: 1823 VSSRVSEKIQQLVQTLKRPKRRPLPEYFQEDENLAVLTTFEDPNAPKPKGTVIEPAIGESLNMLSGLPRSLESALQSYAQAHGKQSVMSCIDSNGRVNGISLTYTKLL 2146
            V+SRVS KIQQL+ TLKRPKR PL E+F +D    V     DPN PKP+G  + P  GE L ++   P +LESALQ +     K   ++ +D  G+    +LTY KL 
Sbjct:   33 VNSRVSTKIQQLLNTLKRPKRPPLKEFFVDDSEEIVEVPQPDPNQPKPEGRQMTPVKGEPLGVICNWPPALESALQRWGSTQAKCPCLTGLDVTGK-PVYTLTYGKLW 139          
BLAST of SMED30009414 vs. Ensembl Mouse
Match: Dip2b (disco interacting protein 2 homolog B [Source:MGI Symbol;Acc:MGI:2145977])

HSP 1 Score: 85.1149 bits (209), Expect = 2.840e-16
Identity = 49/109 (44.95%), Postives = 65/109 (59.63%), Query Frame = -1
Query: 1823 VSSRVSEKIQQLVQTLKRPKRRPLPEYFQED-ENLAVLTTFEDPNAPKPKGTVIEPAIGESLNMLSGLPRSLESALQSYAQAHGKQSVMSCIDSNGRVNGISLTYTKLL 2146
            V+SRVS KIQQL+ TLKRPKR PL E+F +D E +       DPN PKP+G  + P  GE L ++   P +LESALQ +     K   ++ +D  G+    +LTY KL 
Sbjct:  266 VNSRVSTKIQQLLNTLKRPKRPPLKEFFVDDSEEIVEGIPQPDPNQPKPEGRQMTPVKGEPLGVICNWPPALESALQRWGSTQAKCPCLTGLDVTGK-PVYTLTYGKLW 373          
BLAST of SMED30009414 vs. UniProt/SwissProt
Match: sp|Q9W0S9|DIP2_DROME (Disco-interacting protein 2 OS=Drosophila melanogaster OX=7227 GN=DIP2 PE=1 SV=2)

HSP 1 Score: 107.071 bits (266), Expect = 3.252e-22
Identity = 54/106 (50.94%), Postives = 74/106 (69.81%), Query Frame = -1
Query: 1823 RVSEKIQQLVQTLKRPKRRPLPEYFQE-DENLAVLTTFEDPNAPKPKGTVIEPAIGESLNMLSGLPRSLESALQSYAQAHGKQSVMSCIDSNGRVNGISLTYTKLL 2137
            +VS KIQQL+ TLKRPKRRPLPE++++ D  L +    +DPNAPKP+G+ + P  GE L++ +GLPR+LE ALQ Y     K  + + +D NG+V   +LTY KLL
Sbjct:  381 KVSAKIQQLLNTLKRPKRRPLPEFYEDNDIELEIAANTKDPNAPKPEGSTMTPVQGEQLSIPAGLPRTLECALQRYGTNSFKSPMATVLDPNGKVT-TTLTYGKLL 485          
BLAST of SMED30009414 vs. UniProt/SwissProt
Match: sp|Q9P265|DIP2B_HUMAN (Disco-interacting protein 2 homolog B OS=Homo sapiens OX=9606 GN=DIP2B PE=1 SV=3)

HSP 1 Score: 93.2041 bits (230), Expect = 5.556e-18
Identity = 51/108 (47.22%), Postives = 65/108 (60.19%), Query Frame = -1
Query: 1823 VSSRVSEKIQQLVQTLKRPKRRPLPEYFQEDENLAVLTTFEDPNAPKPKGTVIEPAIGESLNMLSGLPRSLESALQSYAQAHGKQSVMSCIDSNGRVNGISLTYTKLL 2146
            VSSRVS KIQQL+ TLKRPKR PL E+F +D    V     DPN PKP+G  + P  GE L ++   P +LESALQ +     K S ++ +D  G+    +LTY KL 
Sbjct:  269 VSSRVSTKIQQLLNTLKRPKRPPLKEFFVDDSEEIVEVPQPDPNQPKPEGRQMTPVKGEPLGVICNWPPALESALQRWGTTQAKCSCLTALDMTGK-PVYTLTYGKLW 375          
BLAST of SMED30009414 vs. UniProt/SwissProt
Match: sp|Q9Y2E4|DIP2C_HUMAN (Disco-interacting protein 2 homolog C OS=Homo sapiens OX=9606 GN=DIP2C PE=1 SV=2)

HSP 1 Score: 92.4337 bits (228), Expect = 1.124e-17
Identity = 66/176 (37.50%), Postives = 94/176 (53.41%), Query Frame = -1
Query: 1823 HGVPPDVTSHTPNALKDQNSVTTDSITSSIGDNIRRSRDDASCPSQTGSVNSLQTGGTNNGAVENGL-VSSRVSEKIQQLVQTLKRPKRRPLPEYFQEDENLAVLTTFEDPNAPKPKGTVIEPAIGESLNMLSGLPRSLESALQSYAQAHGKQSVMSCIDSNGRVNGISLTYTKLL 2347
            H  PPDVT++T      ++S+  +    S G          + P + G+   ++TG        +G+ VSSRVS KIQQLV TLKRPKR PL E+F +D    +     DPN PKP+G  +    GE L +++  P SLE+ALQ +     K   ++ +D+NG+   I LTY KL 
Sbjct:  204 HSAPPDVTTYT-----SEHSIQVERPQGSTGSR--------TAP-KYGNAELMETG--------DGVPVSSRVSAKIQQLVNTLKRPKRPPLREFFVDDFEELLEVQQPDPNQPKPEGAQMLAMRGEQLGVVTNWPPSLEAALQRWGTISPKAPCLTTMDTNGKPLYI-LTYGKLW 356          
BLAST of SMED30009414 vs. UniProt/SwissProt
Match: sp|Q6NVJ5|DI2BA_DANRE (Disco-interacting protein 2 homolog B-A OS=Danio rerio OX=7955 GN=dip2ba PE=2 SV=1)

HSP 1 Score: 87.8113 bits (216), Expect = 2.892e-16
Identity = 63/173 (36.42%), Postives = 85/173 (49.13%), Query Frame = -1
Query: 1823 VPPDVTSHTPNALKDQNSVTTDSITSSIGDNIRRSRDDASCPSQTGSVNSLQTGGTNNGAVENGLVSSRVSEKIQQLVQTLKRPKRRPLPEYFQEDENLAVLTTFEDPNAPKPKGTVIEPAIGESLNMLSGLPRSLESALQSYAQAHGKQSVMSCIDSNGRVNGISLTYTKLL 2341
            VPPDVTS  P   +D+NS   D   +     I R +  +S     G V +                 SRVS KIQQL+ TLKRPKR PL E+F +D    V     DPN P+P+G  I P  GE L ++S  P +L++AL  +     K   ++ +D  G+    +LTY KL 
Sbjct:  225 VPPDVTSTAP---QDRNS-RVDLPANIAVKGISRGQSRSSMMDTAGGVPA----------------HSRVSTKIQQLLNTLKRPKRPPLSEFFLDDSEEIVEVPQPDPNTPRPEGRQIIPVKGEPLGVVSNWPPALQAALARWGATQAKSPALTALDITGK-PLYTLTYGKLW 376          
BLAST of SMED30009414 vs. UniProt/SwissProt
Match: sp|Q3UH60|DIP2B_MOUSE (Disco-interacting protein 2 homolog B OS=Mus musculus OX=10090 GN=Dip2b PE=1 SV=1)

HSP 1 Score: 85.1149 bits (209), Expect = 1.986e-15
Identity = 49/109 (44.95%), Postives = 65/109 (59.63%), Query Frame = -1
Query: 1823 VSSRVSEKIQQLVQTLKRPKRRPLPEYFQED-ENLAVLTTFEDPNAPKPKGTVIEPAIGESLNMLSGLPRSLESALQSYAQAHGKQSVMSCIDSNGRVNGISLTYTKLL 2146
            V+SRVS KIQQL+ TLKRPKR PL E+F +D E +       DPN PKP+G  + P  GE L ++   P +LESALQ +     K   ++ +D  G+    +LTY KL 
Sbjct:  266 VNSRVSTKIQQLLNTLKRPKRPPLKEFFVDDSEEIVEGIPQPDPNQPKPEGRQMTPVKGEPLGVICNWPPALESALQRWGSTQAKCPCLTGLDVTGK-PVYTLTYGKLW 373          
BLAST of SMED30009414 vs. TrEMBL
Match: A0A0R3WQE3 (Uncharacterized protein OS=Hydatigena taeniaeformis OX=6205 GN=TTAC_LOCUS2968 PE=4 SV=1)

HSP 1 Score: 128.642 bits (322), Expect = 1.026e-28
Identity = 70/134 (52.24%), Postives = 91/134 (67.91%), Query Frame = -1
Query: 1820 PSQTGSVNSLQTGGTNNGAVENGLVS-SRVSEKIQQLVQTLKRPKRRPLPEYFQEDENLAVLTTFEDPNAPKPKGTVIEPAIGESLNMLSGLPRSLESALQSYAQAHGKQSVMSCIDSNGRVNGISLTYTKLLQ 2218
            PS T SV  ++         ++GLV  SRVSEKIQQLV TLKRPKRRPLPEYF ++++  ++    DPNAPKP G + EP IGE L + SGLPR++ESALQ YA   GK   ++C++ +GR   + L+Y KLLQ
Sbjct:   74 PSLTSSV--MEVLPNPQSMYQSGLVCPSRVSEKIQQLVNTLKRPKRRPLPEYFIDEDDQILVQPVVDPNAPKPLGAITEPLIGEKLIVSSGLPRNIESALQRYASVIGKTPALTCLEPSGRSTQV-LSYAKLLQ 204          
BLAST of SMED30009414 vs. TrEMBL
Match: A0A0R3SLG1 (Uncharacterized protein OS=Hymenolepis diminuta OX=6216 GN=HDID_LOCUS5774 PE=4 SV=1)

HSP 1 Score: 125.176 bits (313), Expect = 3.066e-28
Identity = 63/114 (55.26%), Postives = 84/114 (73.68%), Query Frame = -1
Query: 1820 ENGLVS-SRVSEKIQQLVQTLKRPKRRPLPEYFQEDENLAVLTTFEDPNAPKPKGTVIEPAIGESLNMLSGLPRSLESALQSYAQAHGKQSVMSCIDSNGRVNGISLTYTKLLQ 2158
            ++GLV  +RVSEKIQQLV TLKRPKRRPLPEYF ++++  ++    DPNAPKP G V EP IGE L + +GLPR++ESALQ YA   GK   ++C++ +GR   + ++Y KLLQ
Sbjct:   82 QSGLVCPARVSEKIQQLVNTLKRPKRRPLPEYFIDEDDQILVQPVIDPNAPKPLGAVTEPLIGEKLIVPTGLPRNIESALQRYASVIGKTPALTCLEPSGRSTQV-VSYAKLLQ 194          
BLAST of SMED30009414 vs. TrEMBL
Match: A0A2G8L712 (Putative disco-interacting protein 2-like C (Fragment) OS=Stichopus japonicus OX=307972 GN=BSL78_07072 PE=4 SV=1)

HSP 1 Score: 126.716 bits (317), Expect = 9.318e-28
Identity = 67/125 (53.60%), Postives = 92/125 (73.60%), Query Frame = -1
Query: 1823 SLQTGGTNNGAVENGLVSSRVSEKIQQLVQTLKRPKRRPLPEYFQEDENLAVLTTFE-DPNAPKPKGTVIEPAIGESLNMLSGLPRSLESALQSYAQAHGKQSVMSCIDSNGRVNGISLTYTKLL 2194
            + Q GGT    +E+  +S+RVS KIQQL+ TLKRPKR+PL ++F E+++   L TF+ DPNAP+P+G VI PAIG+ L++ +GLPR+LESALQ Y  A  K  V +C+D+NG+V+   LTY KLL
Sbjct:  144 AFQRGGT----IEDPHISARVSSKIQQLLNTLKRPKRKPLQDFFVEEDD--ELETFQMDPNAPRPEGNVITPAIGDQLHIPTGLPRNLESALQRYGTATPKNIVTTCLDANGKVSS-HLTYAKLL 261          
BLAST of SMED30009414 vs. TrEMBL
Match: A0A3P7LL64 (Uncharacterized protein OS=Dibothriocephalus latus OX=60516 GN=DILT_LOCUS9921 PE=4 SV=1)

HSP 1 Score: 125.176 bits (313), Expect = 1.310e-27
Identity = 66/129 (51.16%), Postives = 90/129 (69.77%), Query Frame = -1
Query: 1820 SVNSLQTGGTNNGAVENGLVS-SRVSEKIQQLVQTLKRPKRRPLPEYFQEDENLAVLTTFEDPNAPKPKGTVIEPAIGESLNMLSGLPRSLESALQSYAQAHGKQSVMSCIDSNGRVNGISLTYTKLLQ 2203
            +++S  TG  +      GLV  +RVSEKIQQLV TL+RPKRRPLPEYF ++++  ++   +DPNAP P+G   EP +GE L + SGLPR++ESALQ YA   GK   ++C+D +GR + + LTY KLLQ
Sbjct:   35 TMSSQPTGTVSRQLSTCGLVCPTRVSEKIQQLVNTLQRPKRRPLPEYFIDEDDQVLVQPVQDPNAPCPRGAPTEPLVGEKLVVPSGLPRNIESALQRYAGLIGKTPALTCMDISGR-SVLVLTYAKLLQ 162          
BLAST of SMED30009414 vs. TrEMBL
Match: A0A183B668 (Uncharacterized protein OS=Echinostoma caproni OX=27848 PE=4 SV=1)

HSP 1 Score: 122.865 bits (307), Expect = 1.036e-26
Identity = 65/119 (54.62%), Postives = 85/119 (71.43%), Query Frame = -1
Query: 1817 NGAVENGLVS-SRVSEKIQQLVQTLKRPKRRPLPEYFQEDENLAVLTTFEDPNAPKPKGTVIEPAIGESLNMLSGLPRSLESALQSYAQAHGKQSVMSCIDSNGRVNGISLTYTKLLQV 2170
            N  +++G+V  +RVSEKIQQLV TLKRPKRRPLPEYF ++E+  ++    DP+AP+P+G   +P  GE L + SGLPR+LESALQ YA    K  V++C+D  GR   + LTY KLLQV
Sbjct:  218 NDRMQSGVVCPNRVSEKIQQLVNTLKRPKRRPLPEYFLDEEDQILVRQVTDPSAPRPRGPQSQPLRGEELVVPSGLPRNLESALQRYAGLSCKAPVLTCLDVCGRPTQV-LTYAKLLQV 335          
BLAST of SMED30009414 vs. Ensembl Cavefish
Match: dip2bb (disco-interacting protein 2 homolog B-A-like [Source:NCBI gene;Acc:103044253])

HSP 1 Score: 92.8189 bits (229), Expect = 7.776e-19
Identity = 50/108 (46.30%), Postives = 66/108 (61.11%), Query Frame = -1
Query: 1823 VSSRVSEKIQQLVQTLKRPKRRPLPEYFQEDENLAVLTTFEDPNAPKPKGTVIEPAIGESLNMLSGLPRSLESALQSYAQAHGKQSVMSCIDSNGRVNGISLTYTKLL 2146
            VSSRVS KIQQL+ TLKRPKR PL E+F +D+   V     DPN PKP+G  I P  GE L ++S  P +L++AL  +    GK   ++ +D  G+    +LTY KL 
Sbjct:  296 VSSRVSTKIQQLLNTLKRPKRPPLSEFFMDDQEEIVEVPRPDPNTPKPEGRQIIPVKGEPLGVVSNWPPALQAALARWGATQGKSPALTALDITGK-PLYTLTYGKLW 402          
BLAST of SMED30009414 vs. Ensembl Cavefish
Match: dip2bb (disco-interacting protein 2 homolog B-A-like [Source:NCBI gene;Acc:103044253])

HSP 1 Score: 92.8189 bits (229), Expect = 7.843e-19
Identity = 50/108 (46.30%), Postives = 66/108 (61.11%), Query Frame = -1
Query: 1823 VSSRVSEKIQQLVQTLKRPKRRPLPEYFQEDENLAVLTTFEDPNAPKPKGTVIEPAIGESLNMLSGLPRSLESALQSYAQAHGKQSVMSCIDSNGRVNGISLTYTKLL 2146
            VSSRVS KIQQL+ TLKRPKR PL E+F +D+   V     DPN PKP+G  I P  GE L ++S  P +L++AL  +    GK   ++ +D  G+    +LTY KL 
Sbjct:  296 VSSRVSTKIQQLLNTLKRPKRPPLSEFFMDDQEEIVEVPRPDPNTPKPEGRQIIPVKGEPLGVVSNWPPALQAALARWGATQGKSPALTALDITGK-PLYTLTYGKLW 402          
BLAST of SMED30009414 vs. Ensembl Cavefish
Match: dip2bb (disco-interacting protein 2 homolog B-A-like [Source:NCBI gene;Acc:103044253])

HSP 1 Score: 92.8189 bits (229), Expect = 7.852e-19
Identity = 50/108 (46.30%), Postives = 66/108 (61.11%), Query Frame = -1
Query: 1823 VSSRVSEKIQQLVQTLKRPKRRPLPEYFQEDENLAVLTTFEDPNAPKPKGTVIEPAIGESLNMLSGLPRSLESALQSYAQAHGKQSVMSCIDSNGRVNGISLTYTKLL 2146
            VSSRVS KIQQL+ TLKRPKR PL E+F +D+   V     DPN PKP+G  I P  GE L ++S  P +L++AL  +    GK   ++ +D  G+    +LTY KL 
Sbjct:  302 VSSRVSTKIQQLLNTLKRPKRPPLSEFFMDDQEEIVEVPRPDPNTPKPEGRQIIPVKGEPLGVVSNWPPALQAALARWGATQGKSPALTALDITGK-PLYTLTYGKLW 408          
BLAST of SMED30009414 vs. Ensembl Cavefish
Match: dip2bb (disco-interacting protein 2 homolog B-A-like [Source:NCBI gene;Acc:103044253])

HSP 1 Score: 92.8189 bits (229), Expect = 7.975e-19
Identity = 50/108 (46.30%), Postives = 66/108 (61.11%), Query Frame = -1
Query: 1823 VSSRVSEKIQQLVQTLKRPKRRPLPEYFQEDENLAVLTTFEDPNAPKPKGTVIEPAIGESLNMLSGLPRSLESALQSYAQAHGKQSVMSCIDSNGRVNGISLTYTKLL 2146
            VSSRVS KIQQL+ TLKRPKR PL E+F +D+   V     DPN PKP+G  I P  GE L ++S  P +L++AL  +    GK   ++ +D  G+    +LTY KL 
Sbjct:  302 VSSRVSTKIQQLLNTLKRPKRPPLSEFFMDDQEEIVEVPRPDPNTPKPEGRQIIPVKGEPLGVVSNWPPALQAALARWGATQGKSPALTALDITGK-PLYTLTYGKLW 408          
BLAST of SMED30009414 vs. Ensembl Cavefish
Match: dip2a (disco-interacting protein 2 homolog A [Source:ZFIN;Acc:ZDB-GENE-091204-2])

HSP 1 Score: 87.8113 bits (216), Expect = 3.016e-17
Identity = 62/179 (34.64%), Postives = 93/179 (51.96%), Query Frame = -1
Query: 1799 NSVTTDSITSSIGDNIRRSRDDASCP----------SQTGSVNSLQTGGTNNGAV---ENGL-VSSRVSEKIQQLVQTLKRPKRRPLPEYFQEDENLAVLTTFEDPNAPKPKGTVIEPAIGESLNMLSGLPRSLESALQSYAQAHGKQSVMSCIDSNGRVNGISLTYTKLLQVCFIRSQ 2293
            ++ T  S  + + D +  ++ D  C           SQ  SV  L  G T+  +     +G+ V+SRVS KIQQL+ TLKRPKR PL E+F +D    +     DPN PKP+G  + P  GE + +++  P SL ++LQ +     K   ++ +D+ G+    SLTY KL    + RSQ
Sbjct:   63 HNATASSAATVLADLMAHTQLDNHCAPPDVTGLSERSQVASVRGLTRGYTHTSSTMETADGVPVNSRVSSKIQQLLNTLKRPKRPPLREFFLDDFEELLDVQQPDPNQPKPEGVQMSPLHGEPMGVVTNWPPSLLASLQRWGTTQPKSPCLTALDNAGK-PIYSLTYGKL----WTRSQ 236          
BLAST of SMED30009414 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002071.1 (pep scaffold:Pmarinus_7.0:GL479928:182456:220195:-1 gene:ENSPMAG00000001878.1 transcript:ENSPMAT00000002071.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 92.4337 bits (228), Expect = 1.864e-19
Identity = 54/126 (42.86%), Postives = 74/126 (58.73%), Query Frame = -1
Query: 1781 NGL-VSSRVSEKIQQLVQTLKRPKRRPLPEYFQEDENLAVLTTFEDPNAPKPKGTVIEPAIGESLNMLSGLPRSLESALQSYAQAHGKQSVMSCIDSNGRVNGISLTYTKLLQVCFIRSQFSH*LS 2155
            NG+ V+SRVS KIQQL+ TLKRPKR PL E+F +D +  +     DPN PKP+G    P  GE L +++  P SLE+ALQ +A    K   ++ +D+ GR    SLTY       F + +F   L+
Sbjct:  208 NGMPVNSRVSSKIQQLLNTLKRPKRPPLKEFFVDDFDELLEVPQPDPNQPKPEGAQTTPVKGEPLGVVTNWPPSLEAALQRWATQSAKALCLTALDTTGRPQ-CSLTYV------FFQERFKKILA 326          
BLAST of SMED30009414 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001386.1 (pep scaffold:Pmarinus_7.0:GL477282:11654:68835:-1 gene:ENSPMAG00000001211.1 transcript:ENSPMAT00000001386.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 90.5077 bits (223), Expect = 8.282e-19
Identity = 53/132 (40.15%), Postives = 77/132 (58.33%), Query Frame = -1
Query: 1823 VNSLQTGGTNNGAVENGLVSSRVSEKIQQLVQTLKRPKRRPLPEYFQEDENLAVLTTF------EDPNAPKPKGTVIEPAIGESLNMLSGLPRSLESALQSYAQAHGKQSVMSCIDSNGRVNGISLTYTKLL 2200
            + S +   + NGAV N    S VS KIQQL+ TLKRPKR P+ E + +DE++  L  F      +DPN P+P+G  + P  GE L ++S  P +LE+ALQ +     K   ++ +D+NG+V   +L Y KL 
Sbjct:   33 IQSEERTESGNGAVSN----SHVSSKIQQLLNTLKRPKRVPVKELYTDDEDM--LEAFDDPVPVQDPNRPRPEGAEMVPVQGEPLGVVSNWPSALEAALQRWGIQSAKAPCLTALDTNGKVLN-TLAYGKLF 157          
BLAST of SMED30009414 vs. Ensembl Medaka
Match: dip2ba (disco-interacting protein 2 homolog B-A [Source:NCBI gene;Acc:101163572])

HSP 1 Score: 90.1225 bits (222), Expect = 5.861e-18
Identity = 65/175 (37.14%), Postives = 86/175 (49.14%), Query Frame = -1
Query: 1823 VPPDVTSHTPNALKDQNSVTTDSITSSIGDNIRRSRDDASCPSQTGSVNSLQTG--GTNNGAVENGLVSSRVSEKIQQLVQTLKRPKRRPLPEYFQEDENLAVLTTFEDPNAPKPKGTVIEPAIGESLNMLSGLPRSLESALQSYAQAHGKQSVMSCIDSNGRVNGISLTYTKLL 2341
            VPPDVTS TP                      R +R D   P +  S    ++    T +G  +   VSSRVS KIQQL+ TLKRPKR PL E+F +D    V     DPN PKP+G  I P  GE L ++S  P +L++AL  +     K   ++ +D  G+    +LTY KL 
Sbjct:  227 VPPDVTSSTPQE--------------------RGTRVDIPPPVRGMSRGQSRSSMLDTADGKRKGVPVSSRVSTKIQQLLNTLKRPKRPPLSEFFLDDSEEIVEVPQLDPNTPKPEGRQIIPVKGEPLGVVSNWPPALQAALARWGATQAKSPALTALDITGK-PLYTLTYGKLW 380          
BLAST of SMED30009414 vs. Ensembl Medaka
Match: dip2ba (disco-interacting protein 2 homolog B-A [Source:NCBI gene;Acc:101163572])

HSP 1 Score: 90.1225 bits (222), Expect = 5.933e-18
Identity = 65/175 (37.14%), Postives = 86/175 (49.14%), Query Frame = -1
Query: 1823 VPPDVTSHTPNALKDQNSVTTDSITSSIGDNIRRSRDDASCPSQTGSVNSLQTG--GTNNGAVENGLVSSRVSEKIQQLVQTLKRPKRRPLPEYFQEDENLAVLTTFEDPNAPKPKGTVIEPAIGESLNMLSGLPRSLESALQSYAQAHGKQSVMSCIDSNGRVNGISLTYTKLL 2341
            VPPDVTS TP                      R +R D   P +  S    ++    T +G  +   VSSRVS KIQQL+ TLKRPKR PL E+F +D    V     DPN PKP+G  I P  GE L ++S  P +L++AL  +     K   ++ +D  G+    +LTY KL 
Sbjct:  203 VPPDVTSSTPQE--------------------RGTRVDIPPPVRGMSRGQSRSSMLDTADGKRKGVPVSSRVSTKIQQLLNTLKRPKRPPLSEFFLDDSEEIVEVPQLDPNTPKPEGRQIIPVKGEPLGVVSNWPPALQAALARWGATQAKSPALTALDITGK-PLYTLTYGKLW 356          
BLAST of SMED30009414 vs. Ensembl Medaka
Match: dip2ba (disco-interacting protein 2 homolog B-A [Source:NCBI gene;Acc:101163572])

HSP 1 Score: 90.1225 bits (222), Expect = 5.971e-18
Identity = 65/175 (37.14%), Postives = 86/175 (49.14%), Query Frame = -1
Query: 1823 VPPDVTSHTPNALKDQNSVTTDSITSSIGDNIRRSRDDASCPSQTGSVNSLQTG--GTNNGAVENGLVSSRVSEKIQQLVQTLKRPKRRPLPEYFQEDENLAVLTTFEDPNAPKPKGTVIEPAIGESLNMLSGLPRSLESALQSYAQAHGKQSVMSCIDSNGRVNGISLTYTKLL 2341
            VPPDVTS TP                      R +R D   P +  S    ++    T +G  +   VSSRVS KIQQL+ TLKRPKR PL E+F +D    V     DPN PKP+G  I P  GE L ++S  P +L++AL  +     K   ++ +D  G+    +LTY KL 
Sbjct:  227 VPPDVTSSTPQE--------------------RGTRVDIPPPVRGMSRGQSRSSMLDTADGKRKGVPVSSRVSTKIQQLLNTLKRPKRPPLSEFFLDDSEEIVEVPQLDPNTPKPEGRQIIPVKGEPLGVVSNWPPALQAALARWGATQAKSPALTALDITGK-PLYTLTYGKLW 380          
BLAST of SMED30009414 vs. Ensembl Medaka
Match: dip2ba (disco-interacting protein 2 homolog B-A [Source:NCBI gene;Acc:101163572])

HSP 1 Score: 89.7373 bits (221), Expect = 6.599e-18
Identity = 65/176 (36.93%), Postives = 88/176 (50.00%), Query Frame = -1
Query: 1823 VPPDVTSHTPNALKDQNSVTTDSITSSIGDNIRRSRDDASCPSQTGSVNSLQTGGTNNGAVE--NGL-VSSRVSEKIQQLVQTLKRPKRRPLPEYFQEDENLAVLTTFEDPNAPKPKGTVIEPAIGESLNMLSGLPRSLESALQSYAQAHGKQSVMSCIDSNGRVNGISLTYTKLL 2341
            VPPDVTS TP                      R +R D   P     V  +  G + +  ++  +G+ VSSRVS KIQQL+ TLKRPKR PL E+F +D    V     DPN PKP+G  I P  GE L ++S  P +L++AL  +     K   ++ +D  G+    +LTY KL 
Sbjct:  227 VPPDVTSSTPQE--------------------RGTRVDIPPP-----VRGMSRGQSRSSMLDTADGVPVSSRVSTKIQQLLNTLKRPKRPPLSEFFLDDSEEIVEVPQLDPNTPKPEGRQIIPVKGEPLGVVSNWPPALQAALARWGATQAKSPALTALDITGK-PLYTLTYGKLW 376          
BLAST of SMED30009414 vs. Ensembl Medaka
Match: dip2bb (disco-interacting protein 2 homolog B-A [Source:NCBI gene;Acc:101162194])

HSP 1 Score: 89.7373 bits (221), Expect = 6.941e-18
Identity = 49/108 (45.37%), Postives = 65/108 (60.19%), Query Frame = -1
Query: 1823 VSSRVSEKIQQLVQTLKRPKRRPLPEYFQEDENLAVLTTFEDPNAPKPKGTVIEPAIGESLNMLSGLPRSLESALQSYAQAHGKQSVMSCIDSNGRVNGISLTYTKLL 2146
            VSSRVS KIQQL+ TLKRPK+ PL E+F +D    V     DPN PKP+G  I P  GE L ++S  P +L++AL  +    GK   ++ +D  G+    +LTY KL 
Sbjct:   21 VSSRVSTKIQQLLNTLKRPKKPPLSEFFTDDSEEIVQVPQPDPNTPKPEGRQIIPVKGEPLGVVSNWPPALQAALARWGATQGKSPALTALDITGK-PLYTLTYGKLW 127          
BLAST of SMED30009414 vs. Planmine SMEST
Match: SMESG000042497.1 (SMESG000042497.1)

HSP 1 Score: 1003.05 bits (2592), Expect = 0.000e+0
Identity = 507/507 (100.00%), Postives = 507/507 (100.00%), Query Frame = 3
Query:   69 MNQSNQIYLNFSTTDISVKIIRSTCLGLCISGGXXXXXXXXXXXXKSKNFHRRSLFGLCINLSCIFFVDIILNQIITLVSSINEYWIFPDVVCIIQSTCITIVDTCLSLTLFMLGIDRLISIRANLNGKIKLARGLNADAIILSTLCLWLLSICVSIPLITKTINSTYVSYKFSCGPTMNDNLIYKISLFCLTIGGPGLCVLIMYVYIIKVWCKTKPEIFENVLQGKFQIEKEVNNSICTFVCHFFWLLTVGPYIVWLYIPSIPNSLTVVFVWLRNFYCWLPFFITVIFHKSFRKSFISLLKSDRICSVTTNIDPNPTTSGINSQQNTYSTNLAFTDSRVNNDDKRFSIYSSEYGNSSRSLSYCSSVISSHKTEHLPKVPVMFATVRGVHVINEYFPEISQSTNEENDFPATLCDVHEAGFTDTSDAASMTTNNSFKANKLPNQSEDVKLPAGIIDTFHPDGFKHKRLKRRPQSNSQIKSSLQLAFELPTITSTQNSTLEENTSKIG 1589
            MNQSNQIYLNFSTTDISVKIIRSTCLGLCISGGLFVNILFIVIIFKSKNFHRRSLFGLCINLSCIFFVDIILNQIITLVSSINEYWIFPDVVCIIQSTCITIVDTCLSLTLFMLGIDRLISIRANLNGKIKLARGLNADAIILSTLCLWLLSICVSIPLITKTINSTYVSYKFSCGPTMNDNLIYKISLFCLTIGGPGLCVLIMYVYIIKVWCKTKPEIFENVLQGKFQIEKEVNNSICTFVCHFFWLLTVGPYIVWLYIPSIPNSLTVVFVWLRNFYCWLPFFITVIFHKSFRKSFISLLKSDRICSVTTNIDPNPTTSGINSQQNTYSTNLAFTDSRVNNDDKRFSIYSSEYGNSSRSLSYCSSVISSHKTEHLPKVPVMFATVRGVHVINEYFPEISQSTNEENDFPATLCDVHEAGFTDTSDAASMTTNNSFKANKLPNQSEDVKLPAGIIDTFHPDGFKHKRLKRRPQSNSQIKSSLQLAFELPTITSTQNSTLEENTSKIG
Sbjct:    1 MNQSNQIYLNFSTTDISVKIIRSTCLGLCISGGLFVNILFIVIIFKSKNFHRRSLFGLCINLSCIFFVDIILNQIITLVSSINEYWIFPDVVCIIQSTCITIVDTCLSLTLFMLGIDRLISIRANLNGKIKLARGLNADAIILSTLCLWLLSICVSIPLITKTINSTYVSYKFSCGPTMNDNLIYKISLFCLTIGGPGLCVLIMYVYIIKVWCKTKPEIFENVLQGKFQIEKEVNNSICTFVCHFFWLLTVGPYIVWLYIPSIPNSLTVVFVWLRNFYCWLPFFITVIFHKSFRKSFISLLKSDRICSVTTNIDPNPTTSGINSQQNTYSTNLAFTDSRVNNDDKRFSIYSSEYGNSSRSLSYCSSVISSHKTEHLPKVPVMFATVRGVHVINEYFPEISQSTNEENDFPATLCDVHEAGFTDTSDAASMTTNNSFKANKLPNQSEDVKLPAGIIDTFHPDGFKHKRLKRRPQSNSQIKSSLQLAFELPTITSTQNSTLEENTSKIG 507          
BLAST of SMED30009414 vs. Planmine SMEST
Match: SMESG000017043.1 (SMESG000017043.1)

HSP 1 Score: 365.155 bits (936), Expect = 1.623e-108
Identity = 178/178 (100.00%), Postives = 178/178 (100.00%), Query Frame = -1
Query: 1820 GAHGVPPDVTSHTPNALKDQNSVTTDSITSSIGDNIRRSRDDASCPSQTGSVNSLQTGGTNNGAVENGLVSSRVSEKIQQLVQTLKRPKRRPLPEYFQEDENLAVLTTFEDPNAPKPKGTVIEPAIGESLNMLSGLPRSLESALQSYAQAHGKQSVMSCIDSNGRVNGISLTYTKLLQ 2353
            GAHGVPPDVTSHTPNALKDQNSVTTDSITSSIGDNIRRSRDDASCPSQTGSVNSLQTGGTNNGAVENGLVSSRVSEKIQQLVQTLKRPKRRPLPEYFQEDENLAVLTTFEDPNAPKPKGTVIEPAIGESLNMLSGLPRSLESALQSYAQAHGKQSVMSCIDSNGRVNGISLTYTKLLQ
Sbjct:  266 GAHGVPPDVTSHTPNALKDQNSVTTDSITSSIGDNIRRSRDDASCPSQTGSVNSLQTGGTNNGAVENGLVSSRVSEKIQQLVQTLKRPKRRPLPEYFQEDENLAVLTTFEDPNAPKPKGTVIEPAIGESLNMLSGLPRSLESALQSYAQAHGKQSVMSCIDSNGRVNGISLTYTKLLQ 443          
BLAST of SMED30009414 vs. Planmine SMEST
Match: SMESG000017043.1 (SMESG000017043.1)

HSP 1 Score: 364.77 bits (935), Expect = 1.780e-108
Identity = 178/178 (100.00%), Postives = 178/178 (100.00%), Query Frame = -1
Query: 1820 GAHGVPPDVTSHTPNALKDQNSVTTDSITSSIGDNIRRSRDDASCPSQTGSVNSLQTGGTNNGAVENGLVSSRVSEKIQQLVQTLKRPKRRPLPEYFQEDENLAVLTTFEDPNAPKPKGTVIEPAIGESLNMLSGLPRSLESALQSYAQAHGKQSVMSCIDSNGRVNGISLTYTKLLQ 2353
            GAHGVPPDVTSHTPNALKDQNSVTTDSITSSIGDNIRRSRDDASCPSQTGSVNSLQTGGTNNGAVENGLVSSRVSEKIQQLVQTLKRPKRRPLPEYFQEDENLAVLTTFEDPNAPKPKGTVIEPAIGESLNMLSGLPRSLESALQSYAQAHGKQSVMSCIDSNGRVNGISLTYTKLLQ
Sbjct:  251 GAHGVPPDVTSHTPNALKDQNSVTTDSITSSIGDNIRRSRDDASCPSQTGSVNSLQTGGTNNGAVENGLVSSRVSEKIQQLVQTLKRPKRRPLPEYFQEDENLAVLTTFEDPNAPKPKGTVIEPAIGESLNMLSGLPRSLESALQSYAQAHGKQSVMSCIDSNGRVNGISLTYTKLLQ 428          
The following BLAST results are available for this feature:
BLAST of SMED30009414 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
DIP2B1.157e-1847.22disco interacting protein 2 homolog B [Source:HGNC... [more]
DIP2C2.292e-1837.50disco interacting protein 2 homolog C [Source:HGNC... [more]
DIP2C2.341e-1837.50disco interacting protein 2 homolog C [Source:HGNC... [more]
DIP2C2.539e-1837.50disco interacting protein 2 homolog C [Source:HGNC... [more]
DIP2A4.152e-1441.48disco interacting protein 2 homolog A [Source:HGNC... [more]
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BLAST of SMED30009414 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
dip-25.004e-1335.14Disco-Interacting Protein 2 homolog [Source:UniPr... [more]
dip-25.618e-1335.14Disco-Interacting Protein 2 homolog [Source:UniPr... [more]
dip-21.692e-1134.51Disco-Interacting Protein 2 homolog [Source:UniPr... [more]
dip-22.016e-1134.51Disco-Interacting Protein 2 homolog [Source:UniPr... [more]
dip-24.096e-931.19Disco-Interacting Protein 2 homolog [Source:UniPr... [more]
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BLAST of SMED30009414 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
DIP22.754e-2350.94gene:FBgn0024806 transcript:FBtr0332110[more]
DIP23.135e-2350.94gene:FBgn0024806 transcript:FBtr0332109[more]
DIP23.234e-2350.94gene:FBgn0024806 transcript:FBtr0332108[more]
DIP23.245e-2350.94gene:FBgn0024806 transcript:FBtr0072520[more]
DIP23.404e-2350.94gene:FBgn0024806 transcript:FBtr0305325[more]
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BLAST of SMED30009414 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
dip2ba4.347e-1844.44disco-interacting protein 2 homolog Bb [Source:NCB... [more]
dip2ba4.384e-1844.44disco-interacting protein 2 homolog Bb [Source:NCB... [more]
dip2bb4.384e-1844.44disco-interacting protein 2 homolog Bb [Source:ZFI... [more]
dip2ca7.274e-1843.59disco-interacting protein 2 homolog Ca [Source:ZFI... [more]
dip2ba7.547e-1844.44disco-interacting protein 2 homolog Bb [Source:NCB... [more]
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BLAST of SMED30009414 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
anxa56.236e-1845.37annexin A5 [Source:Xenbase;Acc:XB-GENE-1007295][more]
anxa56.412e-1845.37annexin A5 [Source:Xenbase;Acc:XB-GENE-1007295][more]
anxa56.500e-1845.37annexin A5 [Source:Xenbase;Acc:XB-GENE-1007295][more]
anxa56.778e-1845.37annexin A5 [Source:Xenbase;Acc:XB-GENE-1007295][more]
anxa58.513e-1845.37annexin A5 [Source:Xenbase;Acc:XB-GENE-1007295][more]
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BLAST of SMED30009414 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Dip2c3.807e-1837.22disco interacting protein 2 homolog C [Source:MGI ... [more]
Dip2c4.301e-1837.22disco interacting protein 2 homolog C [Source:MGI ... [more]
Dip2c4.328e-1837.22disco interacting protein 2 homolog C [Source:MGI ... [more]
Dip2b1.895e-1745.37disco interacting protein 2 homolog B [Source:MGI ... [more]
Dip2b2.840e-1644.95disco interacting protein 2 homolog B [Source:MGI ... [more]
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BLAST of SMED30009414 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q9W0S9|DIP2_DROME3.252e-2250.94Disco-interacting protein 2 OS=Drosophila melanoga... [more]
sp|Q9P265|DIP2B_HUMAN5.556e-1847.22Disco-interacting protein 2 homolog B OS=Homo sapi... [more]
sp|Q9Y2E4|DIP2C_HUMAN1.124e-1737.50Disco-interacting protein 2 homolog C OS=Homo sapi... [more]
sp|Q6NVJ5|DI2BA_DANRE2.892e-1636.42Disco-interacting protein 2 homolog B-A OS=Danio r... [more]
sp|Q3UH60|DIP2B_MOUSE1.986e-1544.95Disco-interacting protein 2 homolog B OS=Mus muscu... [more]
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BLAST of SMED30009414 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A0R3WQE31.026e-2852.24Uncharacterized protein OS=Hydatigena taeniaeformi... [more]
A0A0R3SLG13.066e-2855.26Uncharacterized protein OS=Hymenolepis diminuta OX... [more]
A0A2G8L7129.318e-2853.60Putative disco-interacting protein 2-like C (Fragm... [more]
A0A3P7LL641.310e-2751.16Uncharacterized protein OS=Dibothriocephalus latus... [more]
A0A183B6681.036e-2654.62Uncharacterized protein OS=Echinostoma caproni OX=... [more]
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BLAST of SMED30009414 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
dip2bb7.776e-1946.30disco-interacting protein 2 homolog B-A-like [Sour... [more]
dip2bb7.843e-1946.30disco-interacting protein 2 homolog B-A-like [Sour... [more]
dip2bb7.852e-1946.30disco-interacting protein 2 homolog B-A-like [Sour... [more]
dip2bb7.975e-1946.30disco-interacting protein 2 homolog B-A-like [Sour... [more]
dip2a3.016e-1734.64disco-interacting protein 2 homolog A [Source:ZFIN... [more]
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BLAST of SMED30009414 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 2
Match NameE-valueIdentityDescription
ENSPMAT00000002071.11.864e-1942.86pep scaffold:Pmarinus_7.0:GL479928:182456:220195:-... [more]
ENSPMAT00000001386.18.282e-1940.15pep scaffold:Pmarinus_7.0:GL477282:11654:68835:-1 ... [more]
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BLAST of SMED30009414 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of SMED30009414 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of SMED30009414 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
dip2ba5.861e-1837.14disco-interacting protein 2 homolog B-A [Source:NC... [more]
dip2ba5.933e-1837.14disco-interacting protein 2 homolog B-A [Source:NC... [more]
dip2ba5.971e-1837.14disco-interacting protein 2 homolog B-A [Source:NC... [more]
dip2ba6.599e-1836.93disco-interacting protein 2 homolog B-A [Source:NC... [more]
dip2bb6.941e-1845.37disco-interacting protein 2 homolog B-A [Source:NC... [more]
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BLAST of SMED30009414 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 3
Match NameE-valueIdentityDescription
SMESG000042497.10.000e+0100.00SMESG000042497.1[more]
SMESG000017043.11.623e-108100.00SMESG000017043.1[more]
SMESG000017043.11.780e-108100.00SMESG000017043.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30009414 ID=SMED30009414|Name=SMED30009414|organism=Schmidtea mediterranea sexual|type=transcript|length=2392bp
ATTGTTTGTCGTTTCAAATAACGATATATGAATTTTATATGTATTTGATA
TTGGGTATAGATTACTAAATGAATCAATCAAATCAAATTTATTTAAATTT
TTCGACAACAGATATATCGGTTAAAATTATTCGATCAACATGTTTAGGGC
TATGCATCAGTGGTGGCTTATTCGTCAATATTTTATTCATAGTCATTATT
TTCAAGAGTAAAAATTTTCATCGTCGATCTCTTTTTGGTTTATGTATAAA
TCTGTCTTGTATTTTCTTTGTGGATATTATTTTGAATCAAATAATTACAT
TGGTTTCATCGATAAATGAATATTGGATATTCCCCGATGTCGTTTGCATT
ATCCAATCAACGTGCATTACAATTGTTGATACTTGTCTATCGTTGACTCT
GTTTATGCTTGGGATTGACAGATTGATTTCTATTCGCGCTAACCTCAATG
GTAAAATCAAACTTGCCAGAGGACTGAATGCTGATGCAATAATTTTATCC
ACTCTCTGTTTGTGGCTGTTGAGTATTTGTGTTTCTATTCCTCTGATAAC
AAAAACAATAAACAGCACATATGTTAGCTACAAATTCTCGTGTGGTCCAA
CAATGAATGACAATCTTATTTACAAAATCTCGTTGTTTTGCCTGACAATC
GGTGGACCCGGGTTGTGTGTACTGATTATGTACGTTTACATTATTAAAGT
CTGGTGCAAAACCAAACCGGAAATCTTTGAAAATGTTTTACAAGGAAAAT
TTCAAATAGAAAAAGAAGTCAACAATTCGATTTGTACCTTTGTTTGTCAT
TTTTTCTGGTTGCTCACTGTCGGACCGTATATCGTTTGGTTGTACATTCC
ATCGATTCCGAATTCGTTGACAGTTGTGTTTGTTTGGCTGAGGAATTTCT
ATTGTTGGTTGCCTTTTTTTATTACTGTTATTTTCCACAAGTCTTTCAGA
AAAAGTTTCATCAGTTTGCTCAAATCCGATAGAATCTGTTCCGTGACTAC
GAACATTGATCCGAACCCGACAACGTCAGGAATCAATTCACAGCAAAACA
CATATTCGACAAATCTTGCATTTACTGACTCTAGAGTTAACAATGATGAC
AAACGATTCTCGATTTACAGTAGCGAATATGGAAACTCATCTCGTTCTTT
ATCGTATTGTTCGTCAGTCATTTCCAGTCATAAAACCGAACATTTGCCAA
AGGTTCCAGTCATGTTTGCCACTGTTAGAGGAGTTCACGTAATAAATGAA
TACTTTCCGGAAATTTCTCAATCGACAAATGAAGAAAATGATTTCCCAGC
AACTCTATGTGATGTCCACGAAGCGGGATTTACCGATACGTCAGACGCGG
CATCTATGACAACCAATAATTCGTTCAAAGCAAATAAGTTACCAAATCAA
TCAGAAGATGTCAAGCTTCCTGCTGGCATAATTGACACCTTCCACCCTGA
TGGGTTTAAACACAAAAGACTAAAAAGACGACCTCAATCGAATTCTCAAA
TTAAATCATCTTTACAGCTAGCTTTTGAGTTGCCAACTATTACATCAACC
CAGAATTCAACATTAGAGGAGAATACTTCTAAAATAGGAAATACTCCGAA
AAAGCTCAGAAAAAAGAAACGCCCACCTCCTCCTATTCCAGTGAATCATA
ATAATAATGGTAATAATGGTAATAATAATGGCATTTTACTAACGATAAAA
TGGGAAATATTCAAGGCAACACAACTGTCAAAGTAGAGATATTGATAATT
ATTAATAATTAATCGGAATAATAAATGTTGTGATAATTAATGTGAGAATT
GCGAACGAATGAAACATACTTGTAATAATTTCGTGTATGTAAGCGAGATT
CCATTAACTCTGCCATTGCTATCAATGCATGACATGACTGATTGCTTGCC
GTGTGCCTGCGCATATGACTGGAGGGCGCTTTCGAGACTTCGAGGTAGAC
CTGATAGCATATTTAGTGATTCCCCTATTGCCGGCTCTATAACTGTTCCT
TTTGGTTTAGGAGCATTCGGATCTTCAAATGTAGTGAGGACTGCTAAATT
TTCGTCTTCTTGGAAATATTCTGGTAATGGACGTCGTTTCGGACGCTTGA
GAGTTTGCACGAGTTGTTGGATTTTTTCTGACACTCTGCTCGATACGAGT
CCATTTTCAACGGCACCGTTATTCGTGCCTCCAGTCTGTAGGCTGTTTAC
TGAGCCGGTTTGACTTGGACAACTGGCATCATCGCGACTGCGCCGAATAT
TATCTCCAATGGATGATGTAATACTGTCTGTGGTGACCGAGTTCTGATCC
TTTAGCGCATTAGGCGTGTGACTGGTGACATCTGGTGGTACACCGTGCGC
GCCTAATTAATTATAATTTTTACCGTTGTAAATAAGTAGTAG
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protein sequence of SMED30009414-orf-1

>SMED30009414-orf-1 ID=SMED30009414-orf-1|Name=SMED30009414-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=556bp
MNQSNQIYLNFSTTDISVKIIRSTCLGLCISGGLFVNILFIVIIFKSKNF
HRRSLFGLCINLSCIFFVDIILNQIITLVSSINEYWIFPDVVCIIQSTCI
TIVDTCLSLTLFMLGIDRLISIRANLNGKIKLARGLNADAIILSTLCLWL
LSICVSIPLITKTINSTYVSYKFSCGPTMNDNLIYKISLFCLTIGGPGLC
VLIMYVYIIKVWCKTKPEIFENVLQGKFQIEKEVNNSICTFVCHFFWLLT
VGPYIVWLYIPSIPNSLTVVFVWLRNFYCWLPFFITVIFHKSFRKSFISL
LKSDRICSVTTNIDPNPTTSGINSQQNTYSTNLAFTDSRVNNDDKRFSIY
SSEYGNSSRSLSYCSSVISSHKTEHLPKVPVMFATVRGVHVINEYFPEIS
QSTNEENDFPATLCDVHEAGFTDTSDAASMTTNNSFKANKLPNQSEDVKL
PAGIIDTFHPDGFKHKRLKRRPQSNSQIKSSLQLAFELPTITSTQNSTLE
ENTSKIGNTPKKLRKKKRPPPPIPVNHNNNGNNGNNNGILLTIKWEIFKA
TQLSK*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000018Category 4 cell
PLANA:0000026gut
PLANA:0000034epidermis
PLANA:0003116parenchymal cell
Vocabulary: INTERPRO
TermDefinition
IPR017452GPCR_Rhodpsn_7TM
IPR000276GPCR_Rhodpsn
Vocabulary: biological process
TermDefinition
GO:0007186G-protein coupled receptor signaling pathway
Vocabulary: cellular component
TermDefinition
GO:0016021integral component of membrane
Vocabulary: molecular function
TermDefinition
GO:0004930G-protein coupled receptor activity
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR000276G protein-coupled receptor, rhodopsin-likePRINTSPR00237GPCRRHODOPSNcoord: 265..289
score: 24.1
coord: 140..161
score: 20.71
coord: 100..122
score: 22.32
coord: 21..45
score: 20.22
coord: 186..209
score: 19.18
IPR000276G protein-coupled receptor, rhodopsin-likePFAMPF000017tm_1coord: 37..291
e-value: 2.5E-9
score: 36.9
NoneNo IPR availableGENE3DG3DSA:1.20.1070.10coord: 2..342
e-value: 2.1E-20
score: 74.4
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 495..528
NoneNo IPR availablePANTHERPTHR45695FAMILY NOT NAMEDcoord: 13..347
NoneNo IPR availableCDDcd006377tm_classA_rhodopsin-likecoord: 22..288
e-value: 1.28229E-17
score: 80.7846
NoneNo IPR availableSUPERFAMILYSSF81321Family A G protein-coupled receptor-likecoord: 8..321
NoneNo IPR availableTMHMMTMhelixcoord: 267..289
NoneNo IPR availableTMHMMTMhelixcoord: 187..209
NoneNo IPR availableTMHMMTMhelixcoord: 20..42
NoneNo IPR availableTMHMMTMhelixcoord: 135..157
NoneNo IPR availableTMHMMTMhelixcoord: 55..77
NoneNo IPR availableTMHMMTMhelixcoord: 92..114
NoneNo IPR availableTMHMMTMhelixcoord: 241..263
IPR017452GPCR, rhodopsin-like, 7TMPROSITEPS50262G_PROTEIN_RECEP_F1_2coord: 36..289
score: 13.972