EF-hand calcium binding domain 2

Overview


Name	EF-hand calcium binding domain 2
Smed ID	SMED30009282
Length (bp)	812

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of EF-hand calcium binding domain 2 (SMED30009282) t-SNE clustered cells

Violin plots show distribution of expression levels for EF-hand calcium binding domain 2 (SMED30009282) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of EF-hand calcium binding domain 2 (SMED30009282) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for EF-hand calcium binding domain 2 (SMED30009282) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30009282

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 3

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
pharynx	SMED30009282	SMESG000049879.1 SMESG000003119.1	dd_Smed_v4_11976_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
nervous system	SMED30009282	SMESG000049879.1 SMESG000003119.1	dd_Smed_v4_11976_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
head region	SMED30009282	SMESG000049879.1 SMESG000003119.1	dd_Smed_v6_11976_0_1	dd_Smed_v6	PMID:28171748 Stückemann et al., 2017

Note: Hover over icons to view figure legend

Homology

[Close]

BLAST of EF-hand calcium binding domain 2 vs. Ensembl Human
Match: EFCAB2 (EF-hand calcium binding domain 2 [Source:HGNC Symbol;Acc:HGNC:28166])

HSP 1 Score: 204.912 bits (520), Expect = 2.697e-66
Identity = 92/159 (57.86%), Postives = 131/159 (82.39%), Query Frame = 2

Query:   71 EKDSIDVLILEIHDKINAAFEIFDHENNKSVDVREVGTIIRSLGCCPSEAELHDILSEMEKPEPTGVVAYEDFLPLMSKILLEKRYKPRHEDELLKAFQALDVEDKGFLTEDQLKKYLMEEGEVFNQDEIEEMLSKAIEPETGKINYKSFVSELVIDDS 547
            EKD  ++++ E H KI  AFE+FDHE+N +VDVRE+GTIIRSLGCCP+E ELHD+++E+E+ EPTG + +E FLP+M++ILLE++Y+P  ED LL+AF+ LD   +GFLT+D+L KY+ EEGE F+Q+E+EEMLS AI+PE+  INYK +++ +VID++
Sbjct:    4 EKDREEIIVAEFHKKIKEAFEVFDHESNNTVDVREIGTIIRSLGCCPTEGELHDLIAEVEEEEPTGYIRFEKFLPVMTEILLERKYRPIPEDVLLRAFEVLDSAKRGFLTKDELIKYMTEEGEPFSQEEMEEMLSAAIDPESNSINYKDYITMMVIDEN 162

[Close]

BLAST of EF-hand calcium binding domain 2 vs. Ensembl Human
Match: EFCAB2 (EF-hand calcium binding domain 2 [Source:HGNC Symbol;Acc:HGNC:28166])

HSP 1 Score: 202.986 bits (515), Expect = 1.062e-64
Identity = 89/154 (57.79%), Postives = 128/154 (83.12%), Query Frame = 2

Query:   86 DVLILEIHDKINAAFEIFDHENNKSVDVREVGTIIRSLGCCPSEAELHDILSEMEKPEPTGVVAYEDFLPLMSKILLEKRYKPRHEDELLKAFQALDVEDKGFLTEDQLKKYLMEEGEVFNQDEIEEMLSKAIEPETGKINYKSFVSELVIDDS 547
            ++++ E H KI  AFE+FDHE+N +VDVRE+GTIIRSLGCCP+E ELHD+++E+E+ EPTG + +E FLP+M++ILLE++Y+P  ED LL+AF+ LD   +GFLT+D+L KY+ EEGE F+Q+E+EEMLS AI+PE+  INYK +++ +VID++
Sbjct:   68 EIIVAEFHKKIKEAFEVFDHESNNTVDVREIGTIIRSLGCCPTEGELHDLIAEVEEEEPTGYIRFEKFLPVMTEILLERKYRPIPEDVLLRAFEVLDSAKRGFLTKDELIKYMTEEGEPFSQEEMEEMLSAAIDPESNSINYKDYITMMVIDEN 221

[Close]

BLAST of EF-hand calcium binding domain 2 vs. Ensembl Human
Match: EFCAB2 (EF-hand calcium binding domain 2 [Source:HGNC Symbol;Acc:HGNC:28166])

HSP 1 Score: 159.844 bits (403), Expect = 5.175e-49
Identity = 71/121 (58.68%), Postives = 99/121 (81.82%), Query Frame = 2

Query:   71 EKDSIDVLILEIHDKINAAFEIFDHENNKSVDVREVGTIIRSLGCCPSEAELHDILSEMEKPEPTGVVAYEDFLPLMSKILLEKRYKPRHEDELLKAFQALDVEDKGFLTEDQLKKYLMEE 433
            EKD  ++++ E H KI  AFE+FDHE+N +VDVRE+GTIIRSLGCCP+E ELHD+++E+E+ EPTG + +E FLP+M++ILLE++Y+P  ED LL+AF+ LD   +GFLT+D+L KY+ EE
Sbjct:    4 EKDREEIIVAEFHKKIKEAFEVFDHESNNTVDVREIGTIIRSLGCCPTEGELHDLIAEVEEEEPTGYIRFEKFLPVMTEILLERKYRPIPEDVLLRAFEVLDSAKRGFLTKDELIKYMTEE 124

[Close]

BLAST of EF-hand calcium binding domain 2 vs. Ensembl Human
Match: EFCAB2 (EF-hand calcium binding domain 2 [Source:HGNC Symbol;Acc:HGNC:28166])

HSP 1 Score: 159.073 bits (401), Expect = 1.084e-48
Identity = 69/117 (58.97%), Postives = 97/117 (82.91%), Query Frame = 2

Query:   89 VLILEIHDKINAAFEIFDHENNKSVDVREVGTIIRSLGCCPSEAELHDILSEMEKPEPTGVVAYEDFLPLMSKILLEKRYKPRHEDELLKAFQALDVEDKGFLTEDQLKKYLMEEGE 439
            +++ E H KI  AFE+FDHE+N +VDVRE+GTIIRSLGCCP+E ELHD+++E+E+ EPTG + +E FLP+M++ILLE++Y+P  ED LL+AF+ LD   +GFLT+D+L KY+ EEG+
Sbjct:    2 IIVAEFHKKIKEAFEVFDHESNNTVDVREIGTIIRSLGCCPTEGELHDLIAEVEEEEPTGYIRFEKFLPVMTEILLERKYRPIPEDVLLRAFEVLDSAKRGFLTKDELIKYMTEEGK 118

[Close]

BLAST of EF-hand calcium binding domain 2 vs. Ensembl Human
Match: EFCAB2 (EF-hand calcium binding domain 2 [Source:HGNC Symbol;Acc:HGNC:28166])

HSP 1 Score: 156.762 bits (395), Expect = 7.754e-48
Identity = 68/115 (59.13%), Postives = 95/115 (82.61%), Query Frame = 2

Query:   89 VLILEIHDKINAAFEIFDHENNKSVDVREVGTIIRSLGCCPSEAELHDILSEMEKPEPTGVVAYEDFLPLMSKILLEKRYKPRHEDELLKAFQALDVEDKGFLTEDQLKKYLMEE 433
            +++ E H KI  AFE+FDHE+N +VDVRE+GTIIRSLGCCP+E ELHD+++E+E+ EPTG + +E FLP+M++ILLE++Y+P  ED LL+AF+ LD   +GFLT+D+L KY+ EE
Sbjct:    2 IIVAEFHKKIKEAFEVFDHESNNTVDVREIGTIIRSLGCCPTEGELHDLIAEVEEEEPTGYIRFEKFLPVMTEILLERKYRPIPEDVLLRAFEVLDSAKRGFLTKDELIKYMTEE 116

[Close]

BLAST of EF-hand calcium binding domain 2 vs. Ensembl Celegans
Match: cmd-1 (Calmodulin [Source:UniProtKB/Swiss-Prot;Acc:O16305])

HSP 1 Score: 85.8853 bits (211), Expect = 1.259e-20
Identity = 42/134 (31.34%), Postives = 83/134 (61.94%), Query Frame = 2

Query:  125 AFEIFDHENNKSVDVREVGTIIRSLGCCPSEAELHDILSEMEKPEPTGVVAYEDFLPLMSKILLEKRYKPRHEDELLKAFQALDVEDKGFLTEDQLKKYLMEEGEVFNQDEIEEMLSKAIEPETGKINYKSFVS 526
            AF +FD + + ++  +E+GT++RSLG  P+EAEL D+++E++  +  G + + +FL +M++    K      E+E+ +AF+  D +  GF++  +L+  +   GE    +E++EM+ +A     G++NY+ FV+
Sbjct:   16 AFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVD-ADGNGTIDFPEFLTMMAR----KMKDTDSEEEIREAFRVFDKDGNGFISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVT 144

[Close]

BLAST of EF-hand calcium binding domain 2 vs. Ensembl Celegans
Match: cal-2 (CALmodulin related genes; Calmodulin-like protein [Source:UniProtKB/TrEMBL;Acc:G5EEG0])

HSP 1 Score: 79.337 bits (194), Expect = 6.258e-18
Identity = 41/138 (29.71%), Postives = 82/138 (59.42%), Query Frame = 2

Query:  122 AAFEIFDHENNKSVDVREVGTIIRSLGCCPSEAELHDILSEMEKPEPTGVVAYEDFLPLMSKILLEKRYKPRHEDELLK-AFQALDVEDKGFLTEDQLKKYLMEEGEVFNQDEIEEMLSKAIEPETGKINYKSFVSEL 532
            AAF +FD + N S+  +E+G  +RSLG  P+E EL D+++E++  + +G + + +F  +M      KR    ++ E+++ AF+  D +  GF+T D+ + ++   G+ F+  E++E++++      G+I+Y+ F S  
Sbjct:   39 AAFRLFDKDGNGSISSKELGVAMRSLGQNPTEQELLDMVNEVD-IDGSGTIDFGEFCQMM------KRMNKENDSEMIREAFRVFDRDGNGFITADEFRYFMTHMGDQFSDQEVDEIIAEIDIDGDGQIDYEEFASTF 169

[Close]

BLAST of EF-hand calcium binding domain 2 vs. Ensembl Celegans
Match: cmd-1 (Calmodulin [Source:UniProtKB/Swiss-Prot;Acc:O16305])

HSP 1 Score: 66.6254 bits (161), Expect = 7.766e-14
Identity = 35/113 (30.97%), Postives = 68/113 (60.18%), Query Frame = 2

Query:  188 IRSLGCCPSEAELHDILSEMEKPEPTGVVAYEDFLPLMSKILLEKRYKPRHEDELLKAFQALDVEDKGFLTEDQLKKYLMEEGEVFNQDEIEEMLSKAIEPETGKINYKSFVS 526
            +RSLG  P+EAEL D+++E++  +  G + + +FL +M++    K      E+E+ +AF+  D +  GF++  +L+  +   GE    +E++EM+ +A     G++NY+ FV+
Sbjct:    1 MRSLGQNPTEAELQDMINEVD-ADGNGTIDFPEFLTMMAR----KMKDTDSEEEIREAFRVFDKDGNGFISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVT 108

[Close]

BLAST of EF-hand calcium binding domain 2 vs. Ensembl Celegans
Match: cal-1 (Calmodulin-like protein [Source:UniProtKB/Swiss-Prot;Acc:P04630])

HSP 1 Score: 67.0106 bits (162), Expect = 1.852e-13
Identity = 41/151 (27.15%), Postives = 85/151 (56.29%), Query Frame = 2

Query:   74 KDSIDVLILEIHDKINAAFEIFDHENNKSVDVREVGTIIRSLGCCPSEAELHDILSEMEKPEPTGVVAYEDFLPLMSKILLEKRYKPRHEDELLK-AFQALDVEDKGFLTEDQLKKYLMEEGEVFNQDEIEEMLSKAIEPETGKINYKSFV 523
            +D I  L  E  D+   AF +FD + N ++  +E+G  +RSLG  P+E E+ ++++E++  +  G + + +F  +M      KR     + E+++ AF+  D +  G +T  + + +++  G  F+++E++EM+ +      G+I+Y+ FV
Sbjct:   12 EDIIKQLTPEEIDEFREAFMMFDKDGNGTISTKELGIAMRSLGQNPTEQEILEMINEVD-IDGNGQIEFPEFCVMM------KRMMKETDSEMIREAFRVFDKDGNGVITAQEFRYFMVHMGMQFSEEEVDEMIKEVDVDGDGEIDYEEFV 155

[Close]

BLAST of EF-hand calcium binding domain 2 vs. Ensembl Celegans
Match: cal-1 (Calmodulin-like protein [Source:UniProtKB/Swiss-Prot;Acc:P04630])

HSP 1 Score: 66.6254 bits (161), Expect = 2.762e-13
Identity = 40/151 (26.49%), Postives = 87/151 (57.62%), Query Frame = 2

Query:   74 KDSIDVLILEIHDKINAAFEIFDHENNKSVDVREVGTIIRSLGCCPSEAELHDILSEMEKPEPTGVVAYEDFLPLMSKILLEKRYKPRHEDELLK-AFQALDVEDKGFLTEDQLKKYLMEEGEVFNQDEIEEMLSKAIEPETGKINYKSFV 523
            +D I  L  E  D+   AF +FD + N ++  +E+G  +RSLG  P+E E+ ++++E++  +  G + + +F  +M +++ E       + E+++ AF+  D +  G +T  + + +++  G  F+++E++EM+ +      G+I+Y+ FV
Sbjct:   31 EDIIKQLTPEEIDEFREAFMMFDKDGNGTISTKELGIAMRSLGQNPTEQEILEMINEVD-IDGNGQIEFPEFCVMMKRMMKET------DSEMIREAFRVFDKDGNGVITAQEFRYFMVHMGMQFSEEEVDEMIKEVDVDGDGEIDYEEFV 174

[Close]

BLAST of EF-hand calcium binding domain 2 vs. Ensembl Fly
Match: CG11041 (gene:FBgn0034481 transcript:FBtr0300692)

HSP 1 Score: 133.65 bits (335), Expect = 8.010e-39
Identity = 61/142 (42.96%), Postives = 104/142 (73.24%), Query Frame = 2

Query:  113 KINAAFEIFDHENNKSVDVREVGTIIRSLGCCPSEAELHDILSEMEKPEPTGVVAYEDFLPLMSKILLEKRYKPRHEDELLKAFQALDVEDKGFLTEDQLKKYLMEEGEVFNQDEIEEMLSKAIEPETGKINYKSFVSELVI 538
            +I+ AF +FDH  +K +DVREVGT++R LGC P+E E+++++S  E  E +G V    FLP +S++L+E++ +P   +++L+AF+ LD E+KG+LT++   K +MEEGE F Q+E++EM   AI+P +G I Y+ ++++L++
Sbjct:   12 RISDAFCVFDHHGDKFIDVREVGTVLRLLGCVPTEEEVNEVISATESEETSGEVHLTKFLPHVSQLLMERKMEPAPPEKILQAFKILDPENKGYLTKESFGKLMMEEGEPFTQEEMDEMWPVAIDPISGHIPYEFYLNQLMV 153

[Close]

BLAST of EF-hand calcium binding domain 2 vs. Ensembl Fly
Match: CG9406 (gene:FBgn0034592 transcript:FBtr0071570)

HSP 1 Score: 107.457 bits (267), Expect = 2.415e-28
Identity = 53/144 (36.81%), Postives = 92/144 (63.89%), Query Frame = 2

Query:  101 EIHDKINAAFEIFDHENNKSVDVREVGTIIRSLGCCPSEAELHDILSEMEKPEPTGVVAYEDFLPLMSKILLEKRYKPRHEDELLKAFQALDVEDKGFLTEDQLKKYLMEEGEVFNQDEIEEMLSKAIEPETGKINYKSFVSEL 532
            E+ +KI+ AF IFD   +K +D R VG ++R LGC P+E E+ D++   +  +  G      F+  +SK+L++++ +P   ++LL+AF+ LD E+K +LT++   K + EEGE F+ +E++ M   AI+P TG I Y  ++++L
Sbjct:   10 ELEEKISEAFCIFDTHGDKYIDSRNVGNVLRFLGCAPTEKEVEDVIKATDSVDYPGEAHLVKFMEHVSKLLMDRQMEPASSEKLLEAFETLDPENKKYLTKEYFGKLMAEEGEPFSAEELDAMWPVAIDPITGHIPYTFYINQL 153

[Close]

BLAST of EF-hand calcium binding domain 2 vs. Ensembl Fly
Match: Cam (gene:FBgn0000253 transcript:FBtr0304964)

HSP 1 Score: 85.8853 bits (211), Expect = 1.581e-20
Identity = 42/134 (31.34%), Postives = 83/134 (61.94%), Query Frame = 2

Query:  125 AFEIFDHENNKSVDVREVGTIIRSLGCCPSEAELHDILSEMEKPEPTGVVAYEDFLPLMSKILLEKRYKPRHEDELLKAFQALDVEDKGFLTEDQLKKYLMEEGEVFNQDEIEEMLSKAIEPETGKINYKSFVS 526
            AF +FD + + ++  +E+GT++RSLG  P+EAEL D+++E++  +  G + + +FL +M++    K      E+E+ +AF+  D +  GF++  +L+  +   GE    +E++EM+ +A     G++NY+ FV+
Sbjct:   16 AFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVD-ADGNGTIDFPEFLTMMAR----KMKDTDSEEEIREAFRVFDKDGNGFISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVT 144

[Close]

BLAST of EF-hand calcium binding domain 2 vs. Ensembl Fly
Match: Cam (gene:FBgn0000253 transcript:FBtr0088001)

HSP 1 Score: 85.8853 bits (211), Expect = 1.581e-20
Identity = 42/134 (31.34%), Postives = 83/134 (61.94%), Query Frame = 2

Query:  125 AFEIFDHENNKSVDVREVGTIIRSLGCCPSEAELHDILSEMEKPEPTGVVAYEDFLPLMSKILLEKRYKPRHEDELLKAFQALDVEDKGFLTEDQLKKYLMEEGEVFNQDEIEEMLSKAIEPETGKINYKSFVS 526
            AF +FD + + ++  +E+GT++RSLG  P+EAEL D+++E++  +  G + + +FL +M++    K      E+E+ +AF+  D +  GF++  +L+  +   GE    +E++EM+ +A     G++NY+ FV+
Sbjct:   16 AFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVD-ADGNGTIDFPEFLTMMAR----KMKDTDSEEEIREAFRVFDKDGNGFISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVT 144

[Close]

BLAST of EF-hand calcium binding domain 2 vs. Ensembl Fly
Match: Cam (gene:FBgn0000253 transcript:FBtr0304963)

HSP 1 Score: 85.8853 bits (211), Expect = 1.581e-20
Identity = 42/134 (31.34%), Postives = 83/134 (61.94%), Query Frame = 2

Query:  125 AFEIFDHENNKSVDVREVGTIIRSLGCCPSEAELHDILSEMEKPEPTGVVAYEDFLPLMSKILLEKRYKPRHEDELLKAFQALDVEDKGFLTEDQLKKYLMEEGEVFNQDEIEEMLSKAIEPETGKINYKSFVS 526
            AF +FD + + ++  +E+GT++RSLG  P+EAEL D+++E++  +  G + + +FL +M++    K      E+E+ +AF+  D +  GF++  +L+  +   GE    +E++EM+ +A     G++NY+ FV+
Sbjct:   16 AFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVD-ADGNGTIDFPEFLTMMAR----KMKDTDSEEEIREAFRVFDKDGNGFISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVT 144

[Close]

BLAST of EF-hand calcium binding domain 2 vs. Ensembl Zebrafish
Match: efcab2 (EF-hand calcium binding domain 2 [Source:ZFIN;Acc:ZDB-GENE-070521-5])

HSP 1 Score: 186.422 bits (472), Expect = 4.554e-59
Identity = 88/152 (57.89%), Postives = 118/152 (77.63%), Query Frame = 2

Query:   92 LILEIHDKINAAFEIFDHENNKSVDVREVGTIIRSLGCCPSEAELHDILSEMEKPEPTGVVAYEDFLPLMSKILLEKRYKPRHEDELLKAFQALDVEDKGFLTEDQLKKYLMEEGEVFNQDEIEEMLSKAIEPETGKINYKSFVSELVIDDS 547
            +I+E   +I  AF++FDHE+NK+VDVRE+GTIIRSLGC PSEAELHDI+SE+E+ EPTG V YE FLP M+KILLE++++P  ED L++AF+ LD + KG L   +L KYL +EGE F Q+E++EMLS A++P+   I YK FVS +  DD+
Sbjct:   16 IIIETQKRIGNAFDVFDHESNKTVDVREIGTIIRSLGCFPSEAELHDIISELEEEEPTGFVRYEKFLPTMTKILLERKFRPITEDLLIQAFEVLDQQKKGHLEPAELAKYLTQEGEPFTQEEMDEMLSAAVDPDKNVIFYKDFVSMMTYDDT 167

[Close]

BLAST of EF-hand calcium binding domain 2 vs. Ensembl Zebrafish
Match: calm3a (calmodulin 3a (phosphorylase kinase, delta) [Source:ZFIN;Acc:ZDB-GENE-030131-5590])

HSP 1 Score: 83.5741 bits (205), Expect = 1.476e-19
Identity = 41/133 (30.83%), Postives = 82/133 (61.65%), Query Frame = 2

Query:  125 AFEIFDHENNKSVDVREVGTIIRSLGCCPSEAELHDILSEMEKPEPTGVVAYEDFLPLMSKILLEKRYKPRHEDELLKAFQALDVEDKGFLTEDQLKKYLMEEGEVFNQDEIEEMLSKAIEPETGKINYKSFV 523
            AF +FD + + ++  +E+GT++RSLG  P+EAEL D+++E++  +  G + + +FL +M++    K      E+E+ +AF+  D +  G+++  +L+  +   GE    +E++EM+ +A     G++NY+ FV
Sbjct:   16 AFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVD-ADGNGTIDFPEFLTMMAR----KMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFV 143

[Close]

BLAST of EF-hand calcium binding domain 2 vs. Ensembl Zebrafish
Match: calm3b (calmodulin 3b (phosphorylase kinase, delta) [Source:ZFIN;Acc:ZDB-GENE-030131-527])

HSP 1 Score: 83.5741 bits (205), Expect = 1.476e-19
Identity = 41/133 (30.83%), Postives = 82/133 (61.65%), Query Frame = 2

Query:  125 AFEIFDHENNKSVDVREVGTIIRSLGCCPSEAELHDILSEMEKPEPTGVVAYEDFLPLMSKILLEKRYKPRHEDELLKAFQALDVEDKGFLTEDQLKKYLMEEGEVFNQDEIEEMLSKAIEPETGKINYKSFV 523
            AF +FD + + ++  +E+GT++RSLG  P+EAEL D+++E++  +  G + + +FL +M++    K      E+E+ +AF+  D +  G+++  +L+  +   GE    +E++EM+ +A     G++NY+ FV
Sbjct:   16 AFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVD-ADGNGTIDFPEFLTMMAR----KMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFV 143

[Close]

BLAST of EF-hand calcium binding domain 2 vs. Ensembl Zebrafish
Match: calm1b (calmodulin 1b [Source:ZFIN;Acc:ZDB-GENE-030804-2])

HSP 1 Score: 83.5741 bits (205), Expect = 1.476e-19
Identity = 41/133 (30.83%), Postives = 82/133 (61.65%), Query Frame = 2

Query:  125 AFEIFDHENNKSVDVREVGTIIRSLGCCPSEAELHDILSEMEKPEPTGVVAYEDFLPLMSKILLEKRYKPRHEDELLKAFQALDVEDKGFLTEDQLKKYLMEEGEVFNQDEIEEMLSKAIEPETGKINYKSFV 523
            AF +FD + + ++  +E+GT++RSLG  P+EAEL D+++E++  +  G + + +FL +M++    K      E+E+ +AF+  D +  G+++  +L+  +   GE    +E++EM+ +A     G++NY+ FV
Sbjct:   16 AFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVD-ADGNGTIDFPEFLTMMAR----KMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFV 143

[Close]

Query:  125 AFEIFDHENNKSVDVREVGTIIRSLGCCPSEAELHDILSEMEKPEPTGVVAYEDFLPLMSKILLEKRYKPRHEDELLKAFQALDVEDKGFLTEDQLKKYLMEEGEVFNQDEIEEMLSKAIEPETGKINYKSFV 523
            AF +FD + + ++  +E+GT++RSLG  P+EAEL D+++E++  +  G + + +FL +M++    K      E+E+ +AF+  D +  G+++  +L+  +   GE    +E++EM+ +A     G++NY+ FV
Sbjct:   16 AFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVD-ADGNGTIDFPEFLTMMAR----KMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFV 143

[Close]

BLAST of EF-hand calcium binding domain 2 vs. Ensembl Xenopus
Match: EFCAB2 (EF-hand calcium binding domain 2 [Source:NCBI gene;Acc:100489608])

HSP 1 Score: 188.734 bits (478), Expect = 5.458e-60
Identity = 84/158 (53.16%), Postives = 123/158 (77.85%), Query Frame = 2

Query:   71 EKDSIDVLILEIHDKINAAFEIFDHENNKSVDVREVGTIIRSLGCCPSEAELHDILSEMEKPEPTGVVAYEDFLPLMSKILLEKRYKPRHEDELLKAFQALDVEDKGFLTEDQLKKYLMEEGEVFNQDEIEEMLSKAIEPETGKINYKSFVSELVIDD 544
            EK++ + L+ ++  KI  AFE+FDHE NK+VDVRE+GTIIRSL CCP+E ELHD+++E+E+ EPTG + +E FLP+M+K L+E+RY+P  ED LL+AF+ LD + KG+LT ++L KY+ EEGE F Q+E+EEM+S A++PE   + Y+ + + + IDD
Sbjct:    4 EKEAAESLVTDLQKKITEAFEVFDHECNKTVDVREIGTIIRSLECCPTEGELHDMIAEVEEEEPTGYIRFEKFLPMMTKALMERRYRPIPEDILLRAFEVLDEKKKGYLTREELVKYMTEEGEPFTQEEMEEMVSAAVDPEKNVVPYREYAAMMTIDD 161

[Close]

BLAST of EF-hand calcium binding domain 2 vs. Ensembl Xenopus
Match: CALM2 (calmodulin 1 (phosphorylase kinase, delta) [Source:NCBI gene;Acc:100496298])

HSP 1 Score: 83.5741 bits (205), Expect = 1.541e-19
Identity = 41/133 (30.83%), Postives = 82/133 (61.65%), Query Frame = 2

Query:  125 AFEIFDHENNKSVDVREVGTIIRSLGCCPSEAELHDILSEMEKPEPTGVVAYEDFLPLMSKILLEKRYKPRHEDELLKAFQALDVEDKGFLTEDQLKKYLMEEGEVFNQDEIEEMLSKAIEPETGKINYKSFV 523
            AF +FD + + ++  +E+GT++RSLG  P+EAEL D+++E++  +  G + + +FL +M++    K      E+E+ +AF+  D +  G+++  +L+  +   GE    +E++EM+ +A     G++NY+ FV
Sbjct:    9 AFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVD-ADGNGTIDFPEFLTMMAR----KMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFV 136

[Close]

BLAST of EF-hand calcium binding domain 2 vs. Ensembl Xenopus
Match: CALM2 (calmodulin 1 (phosphorylase kinase, delta) [Source:NCBI gene;Acc:100496298])

HSP 1 Score: 83.5741 bits (205), Expect = 1.628e-19
Identity = 41/137 (29.93%), Postives = 83/137 (60.58%), Query Frame = 2

Query:  125 AFEIFDHENNKSVDVREVGTIIRSLGCCPSEAELHDILSEMEKPEPTGVVAYEDFLPLMSKILLEKRYKPRHEDELLKAFQALDVEDKGFLTEDQLKKYLMEEGEVFNQDEIEEMLSKAIEPETGKINYKSFVSELV 535
            AF +FD + + ++  +E+GT++RSLG  P+EAEL D+++E++  +  G + + +FL +M++    K      E+E+ +AF+  D +  G+++  +L+  +   GE    +E++EM+ +A     G++NY+ FV  + 
Sbjct:    5 AFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVD-ADGNGTIDFPEFLTMMAR----KMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMT 136

[Close]

BLAST of EF-hand calcium binding domain 2 vs. Ensembl Xenopus
Match: CALM2 (calmodulin 1 (phosphorylase kinase, delta) [Source:NCBI gene;Acc:100496298])

HSP 1 Score: 83.5741 bits (205), Expect = 2.103e-19
Identity = 41/133 (30.83%), Postives = 82/133 (61.65%), Query Frame = 2

Query:  125 AFEIFDHENNKSVDVREVGTIIRSLGCCPSEAELHDILSEMEKPEPTGVVAYEDFLPLMSKILLEKRYKPRHEDELLKAFQALDVEDKGFLTEDQLKKYLMEEGEVFNQDEIEEMLSKAIEPETGKINYKSFV 523
            AF +FD + + ++  +E+GT++RSLG  P+EAEL D+++E++  +  G + + +FL +M++    K      E+E+ +AF+  D +  G+++  +L+  +   GE    +E++EM+ +A     G++NY+ FV
Sbjct:   16 AFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVD-ADGNGTIDFPEFLTMMAR----KMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFV 143

[Close]

BLAST of EF-hand calcium binding domain 2 vs. Ensembl Xenopus
Match: CALM2 (calmodulin 1 (phosphorylase kinase, delta) [Source:NCBI gene;Acc:100496298])

HSP 1 Score: 83.5741 bits (205), Expect = 2.103e-19
Identity = 41/133 (30.83%), Postives = 82/133 (61.65%), Query Frame = 2

Query:  125 AFEIFDHENNKSVDVREVGTIIRSLGCCPSEAELHDILSEMEKPEPTGVVAYEDFLPLMSKILLEKRYKPRHEDELLKAFQALDVEDKGFLTEDQLKKYLMEEGEVFNQDEIEEMLSKAIEPETGKINYKSFV 523
            AF +FD + + ++  +E+GT++RSLG  P+EAEL D+++E++  +  G + + +FL +M++    K      E+E+ +AF+  D +  G+++  +L+  +   GE    +E++EM+ +A     G++NY+ FV
Sbjct:   16 AFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVD-ADGNGTIDFPEFLTMMAR----KMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFV 143

[Close]

BLAST of EF-hand calcium binding domain 2 vs. Ensembl Mouse
Match: Efcab2 (EF-hand calcium binding domain 2 [Source:MGI Symbol;Acc:MGI:1915476])

HSP 1 Score: 201.445 bits (511), Expect = 4.552e-65
Identity = 87/160 (54.37%), Postives = 129/160 (80.62%), Query Frame = 2

Query:   68 KEKDSIDVLILEIHDKINAAFEIFDHENNKSVDVREVGTIIRSLGCCPSEAELHDILSEMEKPEPTGVVAYEDFLPLMSKILLEKRYKPRHEDELLKAFQALDVEDKGFLTEDQLKKYLMEEGEVFNQDEIEEMLSKAIEPETGKINYKSFVSELVIDDS 547
            ++ +  + LI E+H KI  AFE+FDHE+N +VDVRE+GTIIRSLGCCP+E ELHD ++E+E+ EPTG + +E F+P+M++ L+E+RY+P  ED LL+AF+ LD   +GFLT+D+L KY+ EEGE F+Q+E+EEMLS AI+PE+  INY+ +++ +V+D++
Sbjct:    5 RDAEGTEALIAELHKKIKDAFEVFDHESNNTVDVREIGTIIRSLGCCPTEGELHDFIAEIEEEEPTGYIRFEKFIPVMTRALVERRYRPAAEDILLRAFEVLDPAKRGFLTKDELVKYMTEEGEPFSQEEMEEMLSAAIDPESNTINYRDYITMMVVDEN 164

[Close]

BLAST of EF-hand calcium binding domain 2 vs. Ensembl Mouse
Match: Calml3 (calmodulin-like 3 [Source:MGI Symbol;Acc:MGI:1917655])

HSP 1 Score: 89.3521 bits (220), Expect = 1.223e-21
Identity = 47/137 (34.31%), Postives = 85/137 (62.04%), Query Frame = 2

Query:  125 AFEIFDHENNKSVDVREVGTIIRSLGCCPSEAELHDILSEMEKPEPTGVVAYEDFLPLMSKILLEKRYKPRHEDELLKAFQALDVEDKGFLTEDQLKKYLMEEGEVFNQDEIEEMLSKAIEPETGKINYKSFVSELV 535
            AF +FD + + S+  +E+GT++RSLG  P+EAEL  +++E++K +  G V + +FL +MS+    K      E+E+ +AF+  D +  GF++  +L+  + + GE  + +E++EM+  A     G++NY+ FV  LV
Sbjct:   16 AFSLFDKDGDGSITTQELGTVMRSLGQNPTEAELQGMVNEIDK-DGNGTVDFPEFLTMMSR----KMKDTDSEEEIREAFRVFDKDGNGFVSAAELRHVMTKLGEKLSDEEVDEMIQAADTDGDGQVNYEEFVHMLV 147

[Close]

BLAST of EF-hand calcium binding domain 2 vs. Ensembl Mouse
Match: Calm3 (calmodulin 3 [Source:MGI Symbol;Acc:MGI:103249])

HSP 1 Score: 83.5741 bits (205), Expect = 1.592e-19
Identity = 41/133 (30.83%), Postives = 82/133 (61.65%), Query Frame = 2

Query:  125 AFEIFDHENNKSVDVREVGTIIRSLGCCPSEAELHDILSEMEKPEPTGVVAYEDFLPLMSKILLEKRYKPRHEDELLKAFQALDVEDKGFLTEDQLKKYLMEEGEVFNQDEIEEMLSKAIEPETGKINYKSFV 523
            AF +FD + + ++  +E+GT++RSLG  P+EAEL D+++E++  +  G + + +FL +M++    K      E+E+ +AF+  D +  G+++  +L+  +   GE    +E++EM+ +A     G++NY+ FV
Sbjct:   16 AFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVD-ADGNGTIDFPEFLTMMAR----KMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFV 143

[Close]

BLAST of EF-hand calcium binding domain 2 vs. Ensembl Mouse
Match: Calm1 (calmodulin 1 [Source:MGI Symbol;Acc:MGI:88251])

HSP 1 Score: 83.5741 bits (205), Expect = 1.592e-19
Identity = 41/133 (30.83%), Postives = 82/133 (61.65%), Query Frame = 2

Query:  125 AFEIFDHENNKSVDVREVGTIIRSLGCCPSEAELHDILSEMEKPEPTGVVAYEDFLPLMSKILLEKRYKPRHEDELLKAFQALDVEDKGFLTEDQLKKYLMEEGEVFNQDEIEEMLSKAIEPETGKINYKSFV 523
            AF +FD + + ++  +E+GT++RSLG  P+EAEL D+++E++  +  G + + +FL +M++    K      E+E+ +AF+  D +  G+++  +L+  +   GE    +E++EM+ +A     G++NY+ FV
Sbjct:   16 AFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVD-ADGNGTIDFPEFLTMMAR----KMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFV 143

[Close]

BLAST of EF-hand calcium binding domain 2 vs. Ensembl Mouse
Match: Calm2 (calmodulin 2 [Source:MGI Symbol;Acc:MGI:103250])

HSP 1 Score: 83.5741 bits (205), Expect = 1.592e-19
Identity = 41/133 (30.83%), Postives = 82/133 (61.65%), Query Frame = 2

Query:  125 AFEIFDHENNKSVDVREVGTIIRSLGCCPSEAELHDILSEMEKPEPTGVVAYEDFLPLMSKILLEKRYKPRHEDELLKAFQALDVEDKGFLTEDQLKKYLMEEGEVFNQDEIEEMLSKAIEPETGKINYKSFV 523
            AF +FD + + ++  +E+GT++RSLG  P+EAEL D+++E++  +  G + + +FL +M++    K      E+E+ +AF+  D +  G+++  +L+  +   GE    +E++EM+ +A     G++NY+ FV
Sbjct:   16 AFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVD-ADGNGTIDFPEFLTMMAR----KMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFV 143

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BLAST of EF-hand calcium binding domain 2 vs. UniProt/SwissProt
Match: sp|Q9CQ46|DRC8_MOUSE (Dynein regulatory complex protein 8 OS=Mus musculus OX=10090 GN=Efcab2 PE=1 SV=1)

HSP 1 Score: 201.445 bits (511), Expect = 3.184e-64
Identity = 87/160 (54.37%), Postives = 129/160 (80.62%), Query Frame = 2

Query:   68 KEKDSIDVLILEIHDKINAAFEIFDHENNKSVDVREVGTIIRSLGCCPSEAELHDILSEMEKPEPTGVVAYEDFLPLMSKILLEKRYKPRHEDELLKAFQALDVEDKGFLTEDQLKKYLMEEGEVFNQDEIEEMLSKAIEPETGKINYKSFVSELVIDDS 547
            ++ +  + LI E+H KI  AFE+FDHE+N +VDVRE+GTIIRSLGCCP+E ELHD ++E+E+ EPTG + +E F+P+M++ L+E+RY+P  ED LL+AF+ LD   +GFLT+D+L KY+ EEGE F+Q+E+EEMLS AI+PE+  INY+ +++ +V+D++
Sbjct:    5 RDAEGTEALIAELHKKIKDAFEVFDHESNNTVDVREIGTIIRSLGCCPTEGELHDFIAEIEEEEPTGYIRFEKFIPVMTRALVERRYRPAAEDILLRAFEVLDPAKRGFLTKDELVKYMTEEGEPFSQEEMEEMLSAAIDPESNTINYRDYITMMVVDEN 164

[Close]

BLAST of EF-hand calcium binding domain 2 vs. UniProt/SwissProt
Match: sp|Q5VUJ9|DRC8_HUMAN (Dynein regulatory complex protein 8 OS=Homo sapiens OX=9606 GN=EFCAB2 PE=1 SV=1)

HSP 1 Score: 159.073 bits (401), Expect = 3.184e-46
Identity = 68/116 (58.62%), Postives = 96/116 (82.76%), Query Frame = 2

Query:   86 DVLILEIHDKINAAFEIFDHENNKSVDVREVGTIIRSLGCCPSEAELHDILSEMEKPEPTGVVAYEDFLPLMSKILLEKRYKPRHEDELLKAFQALDVEDKGFLTEDQLKKYLMEE 433
            ++++ E H KI  AFE+FDHE+N +VDVRE+GTIIRSLGCCP+E ELHD+++E+E+ EPTG + +E FLP+M++ILLE++Y+P  ED LL+AF+ LD   +GFLT+D+L KY+ EE
Sbjct:  145 EIIVAEFHKKIKEAFEVFDHESNNTVDVREIGTIIRSLGCCPTEGELHDLIAEVEEEEPTGYIRFEKFLPVMTEILLERKYRPIPEDVLLRAFEVLDSAKRGFLTKDELIKYMTEE 260

[Close]

BLAST of EF-hand calcium binding domain 2 vs. UniProt/SwissProt
Match: sp|P04352|CALM_CHLRE (Calmodulin OS=Chlamydomonas reinhardtii OX=3055 PE=1 SV=2)

HSP 1 Score: 94.3597 bits (233), Expect = 1.554e-22
Identity = 47/133 (35.34%), Postives = 86/133 (64.66%), Query Frame = 2

Query:  125 AFEIFDHENNKSVDVREVGTIIRSLGCCPSEAELHDILSEMEKPEPTGVVAYEDFLPLMSKILLEKRYKPRHEDELLKAFQALDVEDKGFLTEDQLKKYLMEEGEVFNQDEIEEMLSKAIEPETGKINYKSFV 523
            AF +FD + + ++  +E+GT++RSLG  P+EAEL D++SE++  +  G + + +FL LM++    K  +  HEDEL +AF+  D +  GF++  +L+  +   GE  +++E++EM+ +A     G++NY+ FV
Sbjct:   19 AFALFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMISEVD-ADGNGTIDFPEFLMLMAR----KMKETDHEDELREAFKVFDKDGNGFISAAELRHVMTNLGEKLSEEEVDEMIREADVDGDGQVNYEEFV 146

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BLAST of EF-hand calcium binding domain 2 vs. UniProt/SwissProt
Match: sp|P27482|CALL3_HUMAN (Calmodulin-like protein 3 OS=Homo sapiens OX=9606 GN=CALML3 PE=1 SV=2)

HSP 1 Score: 91.6633 bits (226), Expect = 8.776e-22
Identity = 47/137 (34.31%), Postives = 85/137 (62.04%), Query Frame = 2

Query:  125 AFEIFDHENNKSVDVREVGTIIRSLGCCPSEAELHDILSEMEKPEPTGVVAYEDFLPLMSKILLEKRYKPRHEDELLKAFQALDVEDKGFLTEDQLKKYLMEEGEVFNQDEIEEMLSKAIEPETGKINYKSFVSELV 535
            AF +FD + +  +  RE+GT++RSLG  P+EAEL D++SE+++ +  G V + +FL +M++    K     +E+E+ +AF+  D +  GF++  +L+  +   GE  + +E++EM+  A     G++NY+ FV  LV
Sbjct:   16 AFSLFDKDGDGCITTRELGTVMRSLGQNPTEAELRDMMSEIDR-DGNGTVDFPEFLGMMAR----KMKDTDNEEEIREAFRVFDKDGNGFVSAAELRHVMTRLGEKLSDEEVDEMIRAADTDGDGQVNYEEFVRVLV 147

[Close]

BLAST of EF-hand calcium binding domain 2 vs. UniProt/SwissProt
Match: sp|Q8S1Y9|CML1_ORYSJ (Calmodulin-like protein 1 OS=Oryza sativa subsp. japonica OX=39947 GN=CML1 PE=2 SV=1)

HSP 1 Score: 92.0485 bits (227), Expect = 1.943e-21
Identity = 49/133 (36.84%), Postives = 85/133 (63.91%), Query Frame = 2

Query:  125 AFEIFDHENNKSVDVREVGTIIRSLGCCPSEAELHDILSEMEKPEPTGVVAYEDFLPLMSKILLEKRYKPRHEDELLKAFQALDVEDKGFLTEDQLKKYLMEEGEVFNQDEIEEMLSKAIEPETGKINYKSFV 523
            AF +FD + + S+  +E+GT++RSLG  P+EAEL D++SE++  +  G + +++FL LM++ L +K      E+EL +AF+  D +  GF++  +L+  +   GE    +E+ EM+S+A     G+INY+ FV
Sbjct:   16 AFSLFDKDGDGSITTKELGTVMRSLGQNPTEAELQDMISEVD-TDSNGNIEFKEFLGLMARKLRDK----DSEEELKEAFRVFDKDQNGFISATELRHVMANIGERLTDEEVGEMISEADVDGDGQINYEEFV 143

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BLAST of EF-hand calcium binding domain 2 vs. TrEMBL
Match: F7IRX9 (EF-hand calcium binding domain 2 OS=Callithrix jacchus OX=9483 GN=EFCAB2 PE=4 SV=2)

HSP 1 Score: 210.305 bits (534), Expect = 3.702e-65
Identity = 95/159 (59.75%), Postives = 131/159 (82.39%), Query Frame = 2

Query:   71 EKDSIDVLILEIHDKINAAFEIFDHENNKSVDVREVGTIIRSLGCCPSEAELHDILSEMEKPEPTGVVAYEDFLPLMSKILLEKRYKPRHEDELLKAFQALDVEDKGFLTEDQLKKYLMEEGEVFNQDEIEEMLSKAIEPETGKINYKSFVSELVIDDS 547
            EKD  + ++ E H KI  AFE+FDHE+N +VDVRE+GTIIRSLGCCPSE ELHD+++E+E+ EPTG + +E FLP+M++ILLE+RY+P  ED LL+AF+ LD  ++GFLT+D+L KY+ EEGE F+Q+E+EEMLS AI+PE+  INYK ++S +VID++
Sbjct:    4 EKDREETVVAEFHKKIKGAFEVFDHESNNTVDVREIGTIIRSLGCCPSEGELHDLIAEIEEEEPTGYIRFEKFLPVMTEILLERRYRPIPEDVLLRAFEVLDTANRGFLTKDKLIKYMTEEGEPFSQEEMEEMLSAAIDPESNSINYKDYISMMVIDEN 162

[Close]

BLAST of EF-hand calcium binding domain 2 vs. TrEMBL
Match: F7H3C2 (EF-hand calcium-binding domain-containing protein 2 isoform a OS=Callithrix jacchus OX=9483 GN=EFCAB2 PE=2 SV=1)

HSP 1 Score: 208.764 bits (530), Expect = 1.445e-64
Identity = 94/159 (59.12%), Postives = 130/159 (81.76%), Query Frame = 2

Query:   71 EKDSIDVLILEIHDKINAAFEIFDHENNKSVDVREVGTIIRSLGCCPSEAELHDILSEMEKPEPTGVVAYEDFLPLMSKILLEKRYKPRHEDELLKAFQALDVEDKGFLTEDQLKKYLMEEGEVFNQDEIEEMLSKAIEPETGKINYKSFVSELVIDDS 547
            E D  + ++ E H KI  AFE+FDHE+N +VDVRE+GTIIRSLGCCPSE ELHD+++E+E+ EPTG + +E FLP+M++ILLE+RY+P  ED LL+AF+ LD  ++GFLT+D+L KY+ EEGE F+Q+E+EEMLS AI+PE+  INYK ++S +VID++
Sbjct:    4 ETDREETVVAEFHKKIKGAFEVFDHESNNTVDVREIGTIIRSLGCCPSEGELHDLIAEIEEEEPTGYIRFEKFLPVMTEILLERRYRPIPEDVLLRAFEVLDTANRGFLTKDELIKYMTEEGEPFSQEEMEEMLSAAIDPESNSINYKDYISMMVIDEN 162

[Close]

BLAST of EF-hand calcium binding domain 2 vs. TrEMBL
Match: A0A5F4W778 (EF-hand calcium binding domain 2 OS=Callithrix jacchus OX=9483 GN=EFCAB2 PE=4 SV=1)

HSP 1 Score: 208.764 bits (530), Expect = 1.461e-64
Identity = 93/158 (58.86%), Postives = 130/158 (82.28%), Query Frame = 2

Query:   74 KDSIDVLILEIHDKINAAFEIFDHENNKSVDVREVGTIIRSLGCCPSEAELHDILSEMEKPEPTGVVAYEDFLPLMSKILLEKRYKPRHEDELLKAFQALDVEDKGFLTEDQLKKYLMEEGEVFNQDEIEEMLSKAIEPETGKINYKSFVSELVIDDS 547
            +D  + ++ E H KI  AFE+FDHE+N +VDVRE+GTIIRSLGCCPSE ELHD+++E+E+ EPTG + +E FLP+M++ILLE+RY+P  ED LL+AF+ LD  ++GFLT+D+L KY+ EEGE F+Q+E+EEMLS AI+PE+  INYK ++S +VID++
Sbjct:    5 QDRAETVVAEFHKKIKGAFEVFDHESNNTVDVREIGTIIRSLGCCPSEGELHDLIAEIEEEEPTGYIRFEKFLPVMTEILLERRYRPIPEDVLLRAFEVLDTANRGFLTKDKLIKYMTEEGEPFSQEEMEEMLSAAIDPESNSINYKDYISMMVIDEN 162

[Close]

BLAST of EF-hand calcium binding domain 2 vs. TrEMBL
Match: A0A3Q7PJ30 (dynein regulatory complex protein 8 isoform X3 OS=Callorhinus ursinus OX=34884 GN=EFCAB2 PE=4 SV=1)

HSP 1 Score: 208.379 bits (529), Expect = 2.117e-64
Identity = 91/161 (56.52%), Postives = 131/161 (81.37%), Query Frame = 2

Query:   65 NKEKDSIDVLILEIHDKINAAFEIFDHENNKSVDVREVGTIIRSLGCCPSEAELHDILSEMEKPEPTGVVAYEDFLPLMSKILLEKRYKPRHEDELLKAFQALDVEDKGFLTEDQLKKYLMEEGEVFNQDEIEEMLSKAIEPETGKINYKSFVSELVIDDS 547
            +KE++  ++ + E H KI  AFE+FDHE N +VDVRE+GTI+RSLGCCPSE +LHD+L+E+E+ EPTG + +E FLP+M+K+LLE+RY+P  ED LL+AF+ LD   +GFLT+++L KY+ EEGE F+Q+E+EEMLS AI+PE+  I+YK +++ +V+DDS
Sbjct:    4 DKEREGTEIAVAEYHKKIKEAFEVFDHEANNTVDVREIGTIVRSLGCCPSEGQLHDLLAEVEEEEPTGYIRFEKFLPVMTKVLLERRYRPSPEDTLLRAFEVLDPSKRGFLTKEELIKYMTEEGEPFSQEEMEEMLSAAIDPESNSIHYKDYIAMMVVDDS 164

[Close]

BLAST of EF-hand calcium binding domain 2 vs. TrEMBL
Match: A0A2K5RMR5 (Uncharacterized protein OS=Cebus capucinus imitator OX=1737458 PE=4 SV=1)

HSP 1 Score: 207.994 bits (528), Expect = 2.211e-64
Identity = 95/159 (59.75%), Postives = 129/159 (81.13%), Query Frame = 2

Query:   71 EKDSIDVLILEIHDKINAAFEIFDHENNKSVDVREVGTIIRSLGCCPSEAELHDILSEMEKPEPTGVVAYEDFLPLMSKILLEKRYKPRHEDELLKAFQALDVEDKGFLTEDQLKKYLMEEGEVFNQDEIEEMLSKAIEPETGKINYKSFVSELVIDDS 547
            EKD  +  + E H KI  AFE+FDHE+N +VDVRE+GTIIRSLGCCPSE ELHD+++E+E+ EPTG + +E FLP+M++ILLE+RY+P  ED LL+AF+ LD   +GFLT+D+L KY+ EEGE F+Q+E+EEMLS AI+PE+  INYK ++S +VID++
Sbjct:    4 EKDREETAVAEFHKKIKEAFEVFDHESNNTVDVREIGTIIRSLGCCPSEGELHDLIAELEEEEPTGYIRFEKFLPVMTEILLERRYRPIPEDVLLRAFEVLDTAKRGFLTKDELIKYMTEEGEPFSQEEMEEMLSAAIDPESNSINYKDYISMMVIDEN 162

[Close]

BLAST of EF-hand calcium binding domain 2 vs. Ensembl Cavefish
Match: efcab2 (EF-hand calcium binding domain 2 [Source:ZFIN;Acc:ZDB-GENE-070521-5])

HSP 1 Score: 161.384 bits (407), Expect = 1.547e-49
Identity = 77/147 (52.38%), Postives = 112/147 (76.19%), Query Frame = 2

Query:  104 IHDKINAAFEIFDHENNKSVDVREVGTIIRSLGCCPSEAELHDILSEMEKPEPTGVVAYEDFLPLMSKILLEKRYKPRHEDELLKAFQALDVEDKGFLTEDQLKKYLMEEGEVFNQDEIEEMLSKAIEPETGKINYKSFVSELVIDD 544
            +  KI +AF++FDHE N++VDVRE+GTIIRSLG  P+EAELHD+++E+E+ EP G + +E FLP MS+IL+E + +P  ED LL+AF+ LD + KG L  ++L +YL +EG+ F+Q+E+EEMLS A++PE   I Y+ FVS +  D+
Sbjct:    6 VQKKIRSAFDVFDHEQNQTVDVREIGTIIRSLGRFPTEAELHDVIAEIEEEEPAGFIRFEKFLPTMSRILMENKLRPVPEDLLLQAFEVLDQQKKGHLDPEELSRYLTQEGDPFSQEEMEEMLSAALDPEKNLIFYRDFVSMMTADE 152

[Close]

BLAST of EF-hand calcium binding domain 2 vs. Ensembl Cavefish
Match: calm3a (calmodulin [Source:NCBI gene;Acc:103037741])

HSP 1 Score: 83.5741 bits (205), Expect = 1.250e-19
Identity = 41/133 (30.83%), Postives = 82/133 (61.65%), Query Frame = 2

Query:  125 AFEIFDHENNKSVDVREVGTIIRSLGCCPSEAELHDILSEMEKPEPTGVVAYEDFLPLMSKILLEKRYKPRHEDELLKAFQALDVEDKGFLTEDQLKKYLMEEGEVFNQDEIEEMLSKAIEPETGKINYKSFV 523
            AF +FD + + ++  +E+GT++RSLG  P+EAEL D+++E++  +  G + + +FL +M++    K      E+E+ +AF+  D +  G+++  +L+  +   GE    +E++EM+ +A     G++NY+ FV
Sbjct:   16 AFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVD-ADGNGTIDFPEFLTMMAR----KMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFV 143

[Close]

BLAST of EF-hand calcium binding domain 2 vs. Ensembl Cavefish
Match: calm2a (calmodulin [Source:NCBI gene;Acc:103037741])

HSP 1 Score: 83.5741 bits (205), Expect = 1.250e-19
Identity = 41/133 (30.83%), Postives = 82/133 (61.65%), Query Frame = 2

Query:  125 AFEIFDHENNKSVDVREVGTIIRSLGCCPSEAELHDILSEMEKPEPTGVVAYEDFLPLMSKILLEKRYKPRHEDELLKAFQALDVEDKGFLTEDQLKKYLMEEGEVFNQDEIEEMLSKAIEPETGKINYKSFV 523
            AF +FD + + ++  +E+GT++RSLG  P+EAEL D+++E++  +  G + + +FL +M++    K      E+E+ +AF+  D +  G+++  +L+  +   GE    +E++EM+ +A     G++NY+ FV
Sbjct:   16 AFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVD-ADGNGTIDFPEFLTMMAR----KMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFV 143

[Close]

BLAST of EF-hand calcium binding domain 2 vs. Ensembl Cavefish
Match: calm1b (calmodulin [Source:NCBI gene;Acc:103037741])

HSP 1 Score: 83.5741 bits (205), Expect = 1.250e-19
Identity = 41/133 (30.83%), Postives = 82/133 (61.65%), Query Frame = 2

Query:  125 AFEIFDHENNKSVDVREVGTIIRSLGCCPSEAELHDILSEMEKPEPTGVVAYEDFLPLMSKILLEKRYKPRHEDELLKAFQALDVEDKGFLTEDQLKKYLMEEGEVFNQDEIEEMLSKAIEPETGKINYKSFV 523
            AF +FD + + ++  +E+GT++RSLG  P+EAEL D+++E++  +  G + + +FL +M++    K      E+E+ +AF+  D +  G+++  +L+  +   GE    +E++EM+ +A     G++NY+ FV
Sbjct:   16 AFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVD-ADGNGTIDFPEFLTMMAR----KMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFV 143

[Close]

Query:  125 AFEIFDHENNKSVDVREVGTIIRSLGCCPSEAELHDILSEMEKPEPTGVVAYEDFLPLMSKILLEKRYKPRHEDELLKAFQALDVEDKGFLTEDQLKKYLMEEGEVFNQDEIEEMLSKAIEPETGKINYKSFV 523
            AF +FD + + ++  +E+GT++RSLG  P+EAEL D+++E++  +  G + + +FL +M++    K      E+E+ +AF+  D +  G+++  +L+  +   GE    +E++EM+ +A     G++NY+ FV
Sbjct:   16 AFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVD-ADGNGTIDFPEFLTMMAR----KMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFV 143

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BLAST of EF-hand calcium binding domain 2 vs. Ensembl Sea Lamprey
Match: EFCAB2 (EF-hand calcium binding domain 2 [Source:HGNC Symbol;Acc:HGNC:28166])

HSP 1 Score: 98.9821 bits (245), Expect = 1.197e-26
Identity = 45/102 (44.12%), Postives = 74/102 (72.55%), Query Frame = 2

Query:  242 EMEKPEPTGVVAYEDFLPLMSKILLEKRYKPRHEDELLKAFQALDVEDKGFLTEDQLKKYLMEEGEVFNQDEIEEMLSKAIEPETGKINYKSFVSELVIDDS 547
            ++E+ EPTG +  E FLP+++K+L+E+R+    ED +L+AFQ LD E KG+L  ++L +Y+ EEGE F Q+E+EEMLS A++P+   + YK  VS + ++++
Sbjct:    1 QIEEEEPTGYIRLEKFLPMITKVLMERRFNLSGEDAILRAFQVLDSEAKGYLDPEELTRYMTEEGEPFTQEEMEEMLSAAVDPDKNLVFYKDHVSMMAVEEN 102

[Close]

BLAST of EF-hand calcium binding domain 2 vs. Ensembl Sea Lamprey
Match: EFCAB2 (EF-hand calcium binding domain 2 [Source:HGNC Symbol;Acc:HGNC:28166])

HSP 1 Score: 93.5893 bits (231), Expect = 1.121e-24
Identity = 45/102 (44.12%), Postives = 73/102 (71.57%), Query Frame = 2

Query:  242 EMEKPEPTGVVAYEDFLPLMSKILLEKRYKPRHEDELLKAFQALDVEDKGFLTEDQLKKYLMEEGEVFNQDEIEEMLSKAIEPETGKINYKSFVSELVIDDS 547
            ++E+ EPTG +  E FLP+++K+L+E+R     ED +L+AFQ LD E KG+L  ++L +Y+ EEGE F Q+E+EEMLS A++P+   + YK  VS + ++++
Sbjct:    1 QIEEEEPTGYIRLEKFLPMITKVLMERRIP---EDAILRAFQVLDSEAKGYLDPEELTRYMTEEGEPFTQEEMEEMLSAAVDPDKNLVFYKDHVSMMAVEEN 99

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BLAST of EF-hand calcium binding domain 2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006008.1 (pep scaffold:Pmarinus_7.0:GL476713:142259:146509:-1 gene:ENSPMAG00000005430.1 transcript:ENSPMAT00000006008.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 85.1149 bits (209), Expect = 7.112e-21
Identity = 42/133 (31.58%), Postives = 83/133 (62.41%), Query Frame = 2

Query:  125 AFEIFDHENNKSVDVREVGTIIRSLGCCPSEAELHDILSEMEKPEPTGVVAYEDFLPLMSKILLEKRYKPRHEDELLKAFQALDVEDKGFLTEDQLKKYLMEEGEVFNQDEIEEMLSKAIEPETGKINYKSFV 523
            AF +FD + + ++ V+E+GT++RSLG  P+EAEL D+++E++  +  G + + +FL +M++    K      E+E+ +AF+  D +  G+++  +L+  +   GE    +E++EM+ +A     G++NY+ FV
Sbjct:   16 AFSLFDKDGDGTITVKELGTVMRSLGQNPTEAELQDMINEVD-ADGNGTIDFPEFLTMMAR----KMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFV 143

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BLAST of EF-hand calcium binding domain 2 vs. Ensembl Sea Lamprey
Match: CALM3 (calmodulin 3 [Source:HGNC Symbol;Acc:HGNC:1449])

HSP 1 Score: 83.5741 bits (205), Expect = 2.537e-20
Identity = 41/133 (30.83%), Postives = 82/133 (61.65%), Query Frame = 2

Query:  125 AFEIFDHENNKSVDVREVGTIIRSLGCCPSEAELHDILSEMEKPEPTGVVAYEDFLPLMSKILLEKRYKPRHEDELLKAFQALDVEDKGFLTEDQLKKYLMEEGEVFNQDEIEEMLSKAIEPETGKINYKSFV 523
            AF +FD + + ++  +E+GT++RSLG  P+EAEL D+++E++  +  G + + +FL +M++    K      E+E+ +AF+  D +  G+++  +L+  +   GE    +E++EM+ +A     G++NY+ FV
Sbjct:   16 AFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVD-ADGNGTIDFPEFLTMMAR----KMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFV 143

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BLAST of EF-hand calcium binding domain 2 vs. Ensembl Sea Lamprey
Match: CALML3 (calmodulin like 3 [Source:HGNC Symbol;Acc:HGNC:1452])

HSP 1 Score: 83.5741 bits (205), Expect = 2.644e-20
Identity = 41/133 (30.83%), Postives = 82/133 (61.65%), Query Frame = 2

Query:  125 AFEIFDHENNKSVDVREVGTIIRSLGCCPSEAELHDILSEMEKPEPTGVVAYEDFLPLMSKILLEKRYKPRHEDELLKAFQALDVEDKGFLTEDQLKKYLMEEGEVFNQDEIEEMLSKAIEPETGKINYKSFV 523
            AF +FD + + ++  +E+GT++RSLG  P+EAEL D+++E++  +  G + + +FL +M++    K      E+E+ +AF+  D +  G+++  +L+  +   GE    +E++EM+ +A     G++NY+ FV
Sbjct:   16 AFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVD-ADGNGTIDFPEFLTMMAR----KMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFV 143

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BLAST of EF-hand calcium binding domain 2 vs. Ensembl Yeast
Match: CMD1 (Calmodulin; Ca2+ binding protein that regulates Ca2+ independent processes (mitosis, bud growth, actin organization, endocytosis, etc.) and Ca2+ dependent processes (stress-activated pathways), targets include Nuf1p, Myo2p and calcineurin; binds to the Hog1p MAPK in response to hyperosmotic stress; potentiates membrane tubulation and constriction mediated by the Rvs161p-Rvs167p complex; human CALM1 or CALM2 functionally complement repression induced inviability [Source:SGD;Acc:S000000313])

HSP 1 Score: 81.2629 bits (199), Expect = 9.927e-20
Identity = 47/136 (34.56%), Postives = 79/136 (58.09%), Query Frame = 2

Query:  125 AFEIFDHENNKSVDVREVGTIIRSLGCCPSEAELHDILSEMEKPEPTGVVAYEDFLPLMSKILLEKRYKPRHEDELLKAFQALDVEDKGFLTEDQLKKYLMEEGEVFNQDEIEEMLSKAIEPETGKINYKSFVSEL 532
            AF +FD +NN S+   E+ T++RSLG  PSEAE++D+++E++  +    + + +FL LMS+ L         E ELL+AF+  D    G ++  +LK  L   GE     E+++ML + +   +G+IN + F + L
Sbjct:   16 AFALFDKDNNGSISSSELATVMRSLGLSPSEAEVNDLMNEID-VDGNHQIEFSEFLALMSRQL----KSNDSEQELLEAFKVFDKNGDGLISAAELKHVLTSIGEKLTDAEVDDML-REVSDGSGEINIQQFAALL 145

[Close]

BLAST of EF-hand calcium binding domain 2 vs. Ensembl Yeast
Match: CDC31 (Calcium-binding component of the spindle pole body (SPB) half-bridge; required for SPB duplication in mitosis and meiosis II; homolog of mammalian centrin; binds multiubiquitinated proteins and is involved in proteasomal protein degradation [Source:SGD;Acc:S000005783])

HSP 1 Score: 50.0618 bits (118), Expect = 3.576e-8
Identity = 40/145 (27.59%), Postives = 72/145 (49.66%), Query Frame = 2

Query:   92 LILEIHDKINAAFEIFDHENNKSVDVREVGTIIRSLGCCPSEAELHDILSEMEKPEPTGVVAYEDFLPLMSKILLEKRYKPRHEDELLKAFQALDVEDKGFLTEDQLKKYLMEEGEVFNQDEIEEMLSKAIEPETGKINYKSFVS 526
            L+ E   +I  AF +FD  N+  +D  E+   +++LG    + E+ D++ E +  E   ++ Y+DF  +M     EK  K    DE+ +AFQ  D +  G ++   L++   E GE    +E+  M+ +      G+IN   F++
Sbjct:   17 LLEEQKQEIYEAFSLFDMNNDGFLDYHELKVAMKALGFELPKREILDLIDEYD-SEGRHLMKYDDFYIVMG----EKILKRDPLDEIKRAFQLFDDDHTGKISIKNLRRVAKELGETLTDEELRAMIEEFDLDGDGEINENEFIA 156

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BLAST of EF-hand calcium binding domain 2 vs. Ensembl Yeast
Match: MLC1 (Essential light chain for Myo1p; light chain for Myo2p; stabilizes Myo2p by binding to the neck region; interacts with Myo1p, Iqg1p, and Myo2p to coordinate formation and contraction of the actomyosin ring with targeted membrane deposition [Source:SGD;Acc:S000003074])

HSP 1 Score: 48.521 bits (114), Expect = 9.657e-8
Identity = 35/139 (25.18%), Postives = 70/139 (50.36%), Query Frame = 2

Query:  128 FEIFDHENNKSVDVREVGTIIRSLGCCPSEAELHDILSEMEKPEPTGVVAYEDFLPLM--SKILLEKRYKPRHEDELLKAFQALDVEDKGFLTEDQLKKYLMEEGEVFNQDEIEEMLSKAIEPET-GKINYKSFVSELV 535
            F +FD +   ++    +G  +R++G  P+   + DI++          +  +    L+  ++  L+   K + ED  +KAFQ  D E  G ++   L+  L   GE     E++E+L K +E ++ G+I+YK F+ +++
Sbjct:   11 FTLFDKKGQGAIAKDSLGDYLRAIGYNPTNQLVQDIINADSSLRDASSLTLDQITGLIEVNEKELDATTKAKTED-FVKAFQVFDKESTGKVSVGDLRYMLTGLGEKLTDAEVDELL-KGVEVDSNGEIDYKKFIEDVL 147

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BLAST of EF-hand calcium binding domain 2 vs. Ensembl Nematostella
Match: EDO30228 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T1D5])

HSP 1 Score: 197.208 bits (500), Expect = 1.242e-63
Identity = 92/156 (58.97%), Postives = 122/156 (78.21%), Query Frame = 2

Query:   77 DSIDVLILEIHDKINAAFEIFDHENNKSVDVREVGTIIRSLGCCPSEAELHDILSEMEKPEPTGVVAYEDFLPLMSKILLEKRYKPRHEDELLKAFQALDVEDKGFLTEDQLKKYLMEEGEVFNQDEIEEMLSKAIEPETGKINYKSFVSELVIDD 544
            +S D    E+  KI+ AF+IFDHE+NK+VDVREVGTI+RSL CCP+E ELHDIL++ E+ EPTG + +E F P+M KILLE+RYKP  ED+L KAF+ LD + KG+LT ++L KY+ EEGE F Q+E+EEMLS A++PE G I YK FV+ +V++D
Sbjct:   24 ESTDSTTAELQKKISDAFDIFDHESNKTVDVREVGTIVRSLLCCPTEGELHDILADTEEEEPTGYIRFEKFEPVMLKILLERRYKPAPEDQLSKAFEVLDQDKKGYLTTEELTKYMTEEGEAFTQEEVEEMLSAAVDPEKGVIFYKDFVAMMVVED 179

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BLAST of EF-hand calcium binding domain 2 vs. Ensembl Nematostella
Match: EDO33580 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SRU7])

HSP 1 Score: 87.4261 bits (215), Expect = 1.753e-21
Identity = 47/137 (34.31%), Postives = 84/137 (61.31%), Query Frame = 2

Query:  125 AFEIFDHENNKSVDVREVGTIIRSLGCCPSEAELHDILSEMEKPEPTGVVAYEDFLPLMSKILLEKRYKPRHEDELLKAFQALDVEDKGFLTEDQLKKYLMEEGEVFNQDEIEEMLSKAIEPETGKINYKSFVSELV 535
            AF +FD + + +V   E+GT++R+LG  P++ E+ +++ E+++ + +G + +E+FL LMSK    K     +EDEL+ AFQ  D +  G +T  +LK+ L   GE  ++DE+ EM+ +A     G +N + F+  +V
Sbjct:   16 AFSLFDKDGDGTVTTAELGTVMRNLGQNPTDEEIREMIKEVDE-DGSGSIGFEEFLQLMSK----KTKGKSYEDELMAAFQIFDKDGNGSITVTELKEVLDSLGEKLSEDEVGEMIKEADSDGDGTVNIEEFIKMMV 147

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BLAST of EF-hand calcium binding domain 2 vs. Ensembl Nematostella
Match: EDO46606 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RPN8])

HSP 1 Score: 85.1149 bits (209), Expect = 9.675e-21
Identity = 42/133 (31.58%), Postives = 81/133 (60.90%), Query Frame = 2

Query:  125 AFEIFDHENNKSVDVREVGTIIRSLGCCPSEAELHDILSEMEKPEPTGVVAYEDFLPLMSKILLEKRYKPRHEDELLKAFQALDVEDKGFLTEDQLKKYLMEEGEVFNQDEIEEMLSKAIEPETGKINYKSFV 523
            AF +FD + + ++  +E+GT++RSLG  P+EAEL D+++E++  +  G + + +FL +M++    K      E+E+ +AF+  D +  GF++  +L+  +   GE    +E++EM+ +A     G++NY  FV
Sbjct:    7 AFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVD-ADGNGTIDFPEFLTMMAR----KMKNTDSEEEIREAFRVFDKDGNGFISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYDEFV 134

[Close]

BLAST of EF-hand calcium binding domain 2 vs. Ensembl Nematostella
Match: EDO46518 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RPI8])

HSP 1 Score: 85.1149 bits (209), Expect = 1.392e-20
Identity = 42/133 (31.58%), Postives = 82/133 (61.65%), Query Frame = 2

Query:  125 AFEIFDHENNKSVDVREVGTIIRSLGCCPSEAELHDILSEMEKPEPTGVVAYEDFLPLMSKILLEKRYKPRHEDELLKAFQALDVEDKGFLTEDQLKKYLMEEGEVFNQDEIEEMLSKAIEPETGKINYKSFV 523
            AF +FD + + ++  +E+GT++RSLG  P+EAEL D+++E++  +  G + + +FL +M++    K      E+E+ +AF+  D +  GF++  +L+  +   GE    +E++EM+ +A     G++NY+ FV
Sbjct:   16 AFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVD-ADGNGTIDFPEFLTMMAR----KMKDTDSEEEIREAFRVFDKDGNGFISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFV 143

[Close]

BLAST of EF-hand calcium binding domain 2 vs. Ensembl Nematostella
Match: EDO48778 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RIA0])

HSP 1 Score: 79.7221 bits (195), Expect = 1.321e-18
Identity = 47/146 (32.19%), Postives = 83/146 (56.85%), Query Frame = 2

Query:   86 DVLILEIHDKINAAFEIFDHENNKSVDVREVGTIIRSLGCCPSEAELHDILSEMEKPEPTGVVAYEDFLPLMSKILLEKRYKPRHEDELLKAFQALDVEDKGFLTEDQLKKYLMEEGEVFNQDEIEEMLSKAIEPETGKINYKSFV 523
            D L  E  D+   AF+ FD + N  +  RE+G I+RSLG  P+E EL D+++E++  +  GVV + +F+ +M    + +      ++ELL+AF+  D +DKG++  ++++  L   GE   + +I ++L  A      KI ++ FV
Sbjct:    5 DKLTEEQIDEYRDAFKFFDKDGNGHITTRELGAIMRSLGQNPTENELQDMVNEVDY-DGNGVVDFHEFVNMM----INQNNNTLDQNELLEAFRTFDGDDKGYIFSNEIRYVLRHMGENIPEHDINDILKDASHGRKRKITFEEFV 145

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BLAST of EF-hand calcium binding domain 2 vs. Ensembl Medaka
Match: ENSORLT00000013873.2 (EF-hand calcium binding domain 2 [Source:NCBI gene;Acc:101160149])

HSP 1 Score: 130.183 bits (326), Expect = 7.876e-37
Identity = 66/155 (42.58%), Postives = 105/155 (67.74%), Query Frame = 2

Query:   80 SIDVLIL-EIHDKINAAFEIFDHENNKSVDVREVGTIIRSLGCCPSEAELHDILSEMEKPEPTGVVAYEDFLPLMSKILLEKRYKPRHEDELLKAFQALDVEDKGFLTEDQLKKYLMEEGEVFNQDEIEEMLSKAIEPETGKINYKSFVSELVID 541
            S+ VL L EI  KI AAF +FDH+ + +VDVREV TII SLGC P++A++H  + E+E+ +  G V  + FLP+M+K+++E ++ P  E+ L +AF+ LD + +G++   +L KY+  EGE F+Q+E  EML+  ++ +   I YK  +++L ID
Sbjct:   40 SLFVLWLSEIQRKIRAAFHVFDHKADNTVDVREVSTIIYSLGCFPTKADIHRFVDEVEE-DNMGYVHLDKFLPVMTKVIMENKFPPIPEEHLRQAFEVLDKDRRGYMEPQELAKYMKSEGEAFSQEETNEMLTALVDEKKNLICYKELINQLTID 193

[Close]

BLAST of EF-hand calcium binding domain 2 vs. Ensembl Medaka
Match: calm2a (calmodulin 2 [Source:NCBI gene;Acc:100049420])

HSP 1 Score: 83.5741 bits (205), Expect = 1.243e-19
Identity = 41/133 (30.83%), Postives = 82/133 (61.65%), Query Frame = 2

Query:  125 AFEIFDHENNKSVDVREVGTIIRSLGCCPSEAELHDILSEMEKPEPTGVVAYEDFLPLMSKILLEKRYKPRHEDELLKAFQALDVEDKGFLTEDQLKKYLMEEGEVFNQDEIEEMLSKAIEPETGKINYKSFV 523
            AF +FD + + ++  +E+GT++RSLG  P+EAEL D+++E++  +  G + + +FL +M++    K      E+E+ +AF+  D +  G+++  +L+  +   GE    +E++EM+ +A     G++NY+ FV
Sbjct:   16 AFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVD-ADGNGTIDFPEFLTMMAR----KMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFV 143

[Close]

BLAST of EF-hand calcium binding domain 2 vs. Ensembl Medaka
Match: ENSORLT00000008599.2 (calmodulin 3 [Source:NCBI gene;Acc:100049421])

HSP 1 Score: 83.5741 bits (205), Expect = 1.243e-19
Identity = 41/133 (30.83%), Postives = 82/133 (61.65%), Query Frame = 2

Query:  125 AFEIFDHENNKSVDVREVGTIIRSLGCCPSEAELHDILSEMEKPEPTGVVAYEDFLPLMSKILLEKRYKPRHEDELLKAFQALDVEDKGFLTEDQLKKYLMEEGEVFNQDEIEEMLSKAIEPETGKINYKSFV 523
            AF +FD + + ++  +E+GT++RSLG  P+EAEL D+++E++  +  G + + +FL +M++    K      E+E+ +AF+  D +  G+++  +L+  +   GE    +E++EM+ +A     G++NY+ FV
Sbjct:   16 AFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVD-ADGNGTIDFPEFLTMMAR----KMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFV 143

[Close]

BLAST of EF-hand calcium binding domain 2 vs. Ensembl Medaka
Match: calm1b (calmodulin [Source:NCBI gene;Acc:100049419])

HSP 1 Score: 83.5741 bits (205), Expect = 1.243e-19
Identity = 41/133 (30.83%), Postives = 82/133 (61.65%), Query Frame = 2

Query:  125 AFEIFDHENNKSVDVREVGTIIRSLGCCPSEAELHDILSEMEKPEPTGVVAYEDFLPLMSKILLEKRYKPRHEDELLKAFQALDVEDKGFLTEDQLKKYLMEEGEVFNQDEIEEMLSKAIEPETGKINYKSFV 523
            AF +FD + + ++  +E+GT++RSLG  P+EAEL D+++E++  +  G + + +FL +M++    K      E+E+ +AF+  D +  G+++  +L+  +   GE    +E++EM+ +A     G++NY+ FV
Sbjct:   16 AFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVD-ADGNGTIDFPEFLTMMAR----KMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFV 143

[Close]

BLAST of EF-hand calcium binding domain 2 vs. Ensembl Medaka
Match: ENSORLT00000022188.2 (calmodulin [Source:NCBI gene;Acc:100049422])

HSP 1 Score: 82.8037 bits (203), Expect = 3.883e-19
Identity = 41/133 (30.83%), Postives = 82/133 (61.65%), Query Frame = 2

Query:  125 AFEIFDHENNKSVDVREVGTIIRSLGCCPSEAELHDILSEMEKPEPTGVVAYEDFLPLMSKILLEKRYKPRHEDELLKAFQALDVEDKGFLTEDQLKKYLMEEGEVFNQDEIEEMLSKAIEPETGKINYKSFV 523
            AF +FD + + ++  +E+GT++RSLG  P+EAEL D+++E++  +  G + + +FL +M++    K      E+E+ +AF+  D +  G+++  +L+  +   GE    +E++EM+ +A     G++NY+ FV
Sbjct:   30 AFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVD-ADGNGTIDFPEFLTMMAR----KMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFV 157

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BLAST of EF-hand calcium binding domain 2 vs. Planmine SMEST
Match: SMESG000049879.1 (SMESG000049879.1)

HSP 1 Score: 341.273 bits (874), Expect = 2.887e-120
Identity = 170/170 (100.00%), Postives = 170/170 (100.00%), Query Frame = 2

Query:   38 MDNVDKTDGNKEKDSIDVLILEIHDKINAAFEIFDHENNKSVDVREVGTIIRSLGCCPSEAELHDILSEMEKPEPTGVVAYEDFLPLMSKILLEKRYKPRHEDELLKAFQALDVEDKGFLTEDQLKKYLMEEGEVFNQDEIEEMLSKAIEPETGKINYKSFVSELVIDDS 547
            MDNVDKTDGNKEKDSIDVLILEIHDKINAAFEIFDHENNKSVDVREVGTIIRSLGCCPSEAELHDILSEMEKPEPTGVVAYEDFLPLMSKILLEKRYKPRHEDELLKAFQALDVEDKGFLTEDQLKKYLMEEGEVFNQDEIEEMLSKAIEPETGKINYKSFVSELVIDDS
Sbjct:    1 MDNVDKTDGNKEKDSIDVLILEIHDKINAAFEIFDHENNKSVDVREVGTIIRSLGCCPSEAELHDILSEMEKPEPTGVVAYEDFLPLMSKILLEKRYKPRHEDELLKAFQALDVEDKGFLTEDQLKKYLMEEGEVFNQDEIEEMLSKAIEPETGKINYKSFVSELVIDDS 170

[Close]

BLAST of EF-hand calcium binding domain 2 vs. Planmine SMEST
Match: SMESG000034095.1 (SMESG000034095.1)

HSP 1 Score: 85.8853 bits (211), Expect = 1.320e-20
Identity = 42/134 (31.34%), Postives = 83/134 (61.94%), Query Frame = 2

Query:  125 AFEIFDHENNKSVDVREVGTIIRSLGCCPSEAELHDILSEMEKPEPTGVVAYEDFLPLMSKILLEKRYKPRHEDELLKAFQALDVEDKGFLTEDQLKKYLMEEGEVFNQDEIEEMLSKAIEPETGKINYKSFVS 526
            AF +FD + + ++  +E+GT++RSLG  P+EAEL D+++E++  +  G + + +FL +M++    K      E+E+ +AF+  D +  GF++  +L+  +   GE    +E++EM+ +A     G++NY+ FV+
Sbjct:   16 AFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVD-ADGNGTIDFPEFLTMMAR----KMKDTDSEEEIREAFRVFDKDGNGFISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVT 144

[Close]

BLAST of EF-hand calcium binding domain 2 vs. Planmine SMEST
Match: SMESG000010769.1 (SMESG000010769.1)

HSP 1 Score: 85.8853 bits (211), Expect = 1.320e-20
Identity = 42/134 (31.34%), Postives = 83/134 (61.94%), Query Frame = 2

Query:  125 AFEIFDHENNKSVDVREVGTIIRSLGCCPSEAELHDILSEMEKPEPTGVVAYEDFLPLMSKILLEKRYKPRHEDELLKAFQALDVEDKGFLTEDQLKKYLMEEGEVFNQDEIEEMLSKAIEPETGKINYKSFVS 526
            AF +FD + + ++  +E+GT++RSLG  P+EAEL D+++E++  +  G + + +FL +M++    K      E+E+ +AF+  D +  GF++  +L+  +   GE    +E++EM+ +A     G++NY+ FV+
Sbjct:   16 AFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVD-ADGNGTIDFPEFLTMMAR----KMKDTDSEEEIREAFRVFDKDGNGFISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVT 144

[Close]

BLAST of EF-hand calcium binding domain 2 vs. Planmine SMEST
Match: SMESG000042402.1 (SMESG000042402.1)

HSP 1 Score: 69.3218 bits (168), Expect = 1.881e-14
Identity = 40/137 (29.20%), Postives = 76/137 (55.47%), Query Frame = 2

Query:  116 INAAFEIFDHENNKSVDVREVGTIIRSLGCCPSEAELHDILSEMEKPEPTGVVAYEDFLPLMSKILLEKRYKPRHEDELLKAFQALDVEDKGFLTEDQLKKYLMEEGEVFNQDEIEEMLSKAIEPETGKINYKSFVS 526
            I  AF +FD  N   +   ++  +++ LG  P+E E+ D L E++ P  +G + ++ F  ++ +++ E    P  ++EL  AF+ LD E  GF+T  +++  L    +    +E++EM+ +A +   G INY+ FV+
Sbjct:   18 IRQAFLLFDKLNEGKISSSDLSMVLKCLGVDPNEIEMLDCLKELD-PTGSGFIEFDKFNSVIIRMMKE----PFSDEELRDAFRVLDKEGNGFITATEIRHVLTNLCDKLTDEEVDEMIKEADDDGDGMINYEIFVT 149

[Close]

BLAST of EF-hand calcium binding domain 2 vs. Planmine SMEST
Match: SMESG000078272.1 (SMESG000078272.1)

HSP 1 Score: 67.3958 bits (163), Expect = 1.464e-13
Identity = 47/159 (29.56%), Postives = 88/159 (55.35%), Query Frame = 2

Query:   74 KDSIDVLILEIHDKINAAFEIFDHENNKSVDVREVGTIIRSLGCCPSEAELHDILSEMEKPEPTGVVAYEDFLPLMSKILLEKRYKPRH-EDELLKAFQALDVEDKGFLTEDQLKKYLMEEGEVFNQDEIEEMLSKAIEPETGKINYKSFVSELVIDDS 547
            K S+D +  E   ++   F +FD +   ++  +E+G ++R+LG  P+EAEL D++SE++  +  G + +E+F      IL+ +R K    E +L   F+  D    G +T ++LK  +   GEV    EIEE+++       G I+++ F + L+I+++
Sbjct:    7 KTSLDDMTPEQIAEMQEIFSLFDKDGGGTITTQELGAVMRALGQNPTEAELQDMISEID-IDGNGQIDFEEFC-----ILMNRRIKDSDLETDLKDVFKVFDRNGDGKVTRNELKIVMCNIGEVLTDSEIEEIMNLVDINGDGIIDFEEF-NNLMINNA 158

The following BLAST results are available for this feature:

BLAST of EF-hand calcium binding domain 2 vs. Ensembl Human
BLAST of EF-hand calcium binding domain 2 vs. Ensembl Celegans
BLAST of EF-hand calcium binding domain 2 vs. Ensembl Fly
BLAST of EF-hand calcium binding domain 2 vs. Ensembl Zebrafish
BLAST of EF-hand calcium binding domain 2 vs. Ensembl Xenopus
BLAST of EF-hand calcium binding domain 2 vs. Ensembl Mouse
BLAST of EF-hand calcium binding domain 2 vs. UniProt/SwissProt
BLAST of EF-hand calcium binding domain 2 vs. TrEMBL
BLAST of EF-hand calcium binding domain 2 vs. Ensembl Cavefish
BLAST of EF-hand calcium binding domain 2 vs. Ensembl Sea Lamprey
BLAST of EF-hand calcium binding domain 2 vs. Ensembl Yeast
BLAST of EF-hand calcium binding domain 2 vs. Ensembl Nematostella
BLAST of EF-hand calcium binding domain 2 vs. Ensembl Medaka
BLAST of EF-hand calcium binding domain 2 vs. Planmine SMEST

BLAST of EF-hand calcium binding domain 2 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
EFCAB2	2.697e-66	57.86	EF-hand calcium binding domain 2 [Source:HGNC Symb...	[more]
EFCAB2	1.062e-64	57.79	EF-hand calcium binding domain 2 [Source:HGNC Symb...	[more]
EFCAB2	5.175e-49	58.68	EF-hand calcium binding domain 2 [Source:HGNC Symb...	[more]
EFCAB2	1.084e-48	58.97	EF-hand calcium binding domain 2 [Source:HGNC Symb...	[more]
EFCAB2	7.754e-48	59.13	EF-hand calcium binding domain 2 [Source:HGNC Symb...	[more]

BLAST of EF-hand calcium binding domain 2 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
cmd-1	1.259e-20	31.34	Calmodulin [Source:UniProtKB/Swiss-Prot;Acc:O1630...	[more]
cal-2	6.258e-18	29.71	CALmodulin related genes; Calmodulin-like protein ...	[more]
cmd-1	7.766e-14	30.97	Calmodulin [Source:UniProtKB/Swiss-Prot;Acc:O1630...	[more]
cal-1	1.852e-13	27.15	Calmodulin-like protein [Source:UniProtKB/Swiss-P...	[more]
cal-1	2.762e-13	26.49	Calmodulin-like protein [Source:UniProtKB/Swiss-P...	[more]

BLAST of EF-hand calcium binding domain 2 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
CG11041	8.010e-39	42.96	gene:FBgn0034481 transcript:FBtr0300692	[more]
CG9406	2.415e-28	36.81	gene:FBgn0034592 transcript:FBtr0071570	[more]
Cam	1.581e-20	31.34	gene:FBgn0000253 transcript:FBtr0304964	[more]
Cam	1.581e-20	31.34	gene:FBgn0000253 transcript:FBtr0088001	[more]
Cam	1.581e-20	31.34	gene:FBgn0000253 transcript:FBtr0304963	[more]

BLAST of EF-hand calcium binding domain 2 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
efcab2	4.554e-59	57.89	EF-hand calcium binding domain 2 [Source:ZFIN;Acc:...	[more]
calm3a	1.476e-19	30.83	calmodulin 3a (phosphorylase kinase, delta) [Sourc...	[more]
calm3b	1.476e-19	30.83	calmodulin 3b (phosphorylase kinase, delta) [Sourc...	[more]
calm1b	1.476e-19	30.83	calmodulin 1b [Source:ZFIN;Acc:ZDB-GENE-030804-2]	[more]
calm1b	1.476e-19	30.83	calmodulin 1b [Source:ZFIN;Acc:ZDB-GENE-030804-2]	[more]

BLAST of EF-hand calcium binding domain 2 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
EFCAB2	5.458e-60	53.16	EF-hand calcium binding domain 2 [Source:NCBI gene...	[more]
CALM2	1.541e-19	30.83	calmodulin 1 (phosphorylase kinase, delta) [Source...	[more]
CALM2	1.628e-19	29.93	calmodulin 1 (phosphorylase kinase, delta) [Source...	[more]
CALM2	2.103e-19	30.83	calmodulin 1 (phosphorylase kinase, delta) [Source...	[more]
CALM2	2.103e-19	30.83	calmodulin 1 (phosphorylase kinase, delta) [Source...	[more]

BLAST of EF-hand calcium binding domain 2 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Efcab2	4.552e-65	54.38	EF-hand calcium binding domain 2 [Source:MGI Symbo...	[more]
Calml3	1.223e-21	34.31	calmodulin-like 3 [Source:MGI Symbol;Acc:MGI:19176...	[more]
Calm3	1.592e-19	30.83	calmodulin 3 [Source:MGI Symbol;Acc:MGI:103249]	[more]
Calm1	1.592e-19	30.83	calmodulin 1 [Source:MGI Symbol;Acc:MGI:88251]	[more]
Calm2	1.592e-19	30.83	calmodulin 2 [Source:MGI Symbol;Acc:MGI:103250]	[more]

BLAST of EF-hand calcium binding domain 2 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q9CQ46\|DRC8_MOUSE	3.184e-64	54.38	Dynein regulatory complex protein 8 OS=Mus musculu...	[more]
sp\|Q5VUJ9\|DRC8_HUMAN	3.184e-46	58.62	Dynein regulatory complex protein 8 OS=Homo sapien...	[more]
sp\|P04352\|CALM_CHLRE	1.554e-22	35.34	Calmodulin OS=Chlamydomonas reinhardtii OX=3055 PE...	[more]
sp\|P27482\|CALL3_HUMAN	8.776e-22	34.31	Calmodulin-like protein 3 OS=Homo sapiens OX=9606 ...	[more]
sp\|Q8S1Y9\|CML1_ORYSJ	1.943e-21	36.84	Calmodulin-like protein 1 OS=Oryza sativa subsp. j...	[more]

BLAST of EF-hand calcium binding domain 2 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
F7IRX9	3.702e-65	59.75	EF-hand calcium binding domain 2 OS=Callithrix jac...	[more]
F7H3C2	1.445e-64	59.12	EF-hand calcium-binding domain-containing protein ...	[more]
A0A5F4W778	1.461e-64	58.86	EF-hand calcium binding domain 2 OS=Callithrix jac...	[more]
A0A3Q7PJ30	2.117e-64	56.52	dynein regulatory complex protein 8 isoform X3 OS=...	[more]
A0A2K5RMR5	2.211e-64	59.75	Uncharacterized protein OS=Cebus capucinus imitato...	[more]

BLAST of EF-hand calcium binding domain 2 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
efcab2	1.547e-49	52.38	EF-hand calcium binding domain 2 [Source:ZFIN;Acc:...	[more]
calm3a	1.250e-19	30.83	calmodulin [Source:NCBI gene;Acc:103037741]	[more]
calm2a	1.250e-19	30.83	calmodulin [Source:NCBI gene;Acc:103037741]	[more]
calm1b	1.250e-19	30.83	calmodulin [Source:NCBI gene;Acc:103037741]	[more]
calm3a	1.250e-19	30.83	calmodulin [Source:NCBI gene;Acc:103037741]	[more]

BLAST of EF-hand calcium binding domain 2 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5


Match Name	E-value	Identity	Description
EFCAB2	1.197e-26	44.12	EF-hand calcium binding domain 2 [Source:HGNC Symb...	[more]
EFCAB2	1.121e-24	44.12	EF-hand calcium binding domain 2 [Source:HGNC Symb...	[more]
ENSPMAT00000006008.1	7.112e-21	31.58	pep scaffold:Pmarinus_7.0:GL476713:142259:146509:-...	[more]
CALM3	2.537e-20	30.83	calmodulin 3 [Source:HGNC Symbol;Acc:HGNC:1449]	[more]
CALML3	2.644e-20	30.83	calmodulin like 3 [Source:HGNC Symbol;Acc:HGNC:145...	[more]

BLAST of EF-hand calcium binding domain 2 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 3


Match Name	E-value	Identity	Description
CMD1	9.927e-20	34.56	Calmodulin; Ca2+ binding protein that regulates Ca...	[more]
CDC31	3.576e-8	27.59	Calcium-binding component of the spindle pole body...	[more]
MLC1	9.657e-8	25.18	Essential light chain for Myo1p; light chain for M...	[more]

BLAST of EF-hand calcium binding domain 2 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5


Match Name	E-value	Identity	Description
EDO30228	1.242e-63	58.97	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO33580	1.753e-21	34.31	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO46606	9.675e-21	31.58	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO46518	1.392e-20	31.58	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO48778	1.321e-18	32.19	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of EF-hand calcium binding domain 2 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ENSORLT00000013873.2	7.876e-37	42.58	EF-hand calcium binding domain 2 [Source:NCBI gene...	[more]
calm2a	1.243e-19	30.83	calmodulin 2 [Source:NCBI gene;Acc:100049420]	[more]
ENSORLT00000008599.2	1.243e-19	30.83	calmodulin 3 [Source:NCBI gene;Acc:100049421]	[more]
calm1b	1.243e-19	30.83	calmodulin [Source:NCBI gene;Acc:100049419]	[more]
ENSORLT00000022188.2	3.883e-19	30.83	calmodulin [Source:NCBI gene;Acc:100049422]	[more]

BLAST of EF-hand calcium binding domain 2 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000049879.1	2.887e-120	100.00	SMESG000049879.1	[more]
SMESG000034095.1	1.320e-20	31.34	SMESG000034095.1	[more]
SMESG000010769.1	1.320e-20	31.34	SMESG000010769.1	[more]
SMESG000042402.1	1.881e-14	29.20	SMESG000042402.1	[more]
SMESG000078272.1	1.464e-13	29.56	SMESG000078272.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30009282 ID=SMED30009282|Name=EF-hand calcium binding domain 2|organism=Schmidtea mediterranea sexual|type=transcript|length=812bp
TCATTATCTTAGCAACATAATAATTTGAATAAATTCAATGGATAATGTTG
ATAAAACTGACGGTAACAAAGAAAAGGATTCCATTGATGTGCTAATATTA
GAAATTCACGATAAAATAAATGCAGCTTTCGAGATATTTGACCATGAAAA
TAACAAAAGTGTTGATGTAAGGGAAGTGGGTACAATCATTCGCTCATTGG
GATGCTGTCCCAGTGAGGCAGAATTACACGATATACTATCTGAAATGGAA
AAACCTGAACCGACGGGAGTTGTTGCATATGAAGATTTCCTTCCGCTTAT
GTCAAAAATATTATTAGAAAAAAGATATAAACCTCGACATGAAGATGAAC
TATTGAAAGCATTTCAAGCATTGGACGTCGAGGATAAAGGATTTCTCACC
GAAGACCAATTGAAAAAATATTTAATGGAAGAAGGAGAAGTTTTCAATCA
AGACGAAATTGAGGAAATGTTATCAAAAGCAATTGAACCAGAAACTGGCA
AAATTAATTATAAATCTTTTGTCTCTGAACTTGTGATTGACGATTCTTGA
TCCTTAGGTCCCATGATAAATTGAGATGTCTCCTTGATTAGCATTATGAT
TGAGTTTTTGGTTTTCATTTTGTTCCTTTTGATATATTTAGAATTATTAT
TTTCATCCCTTTCCAATGTTAGCTACGTCCATTTCTATTGAATTTCAATA
AGACTTTCCCATCAAAATTCTTTTTAATAAAATCTATAATGGGGGGTGAC
TGGTATACACAGCAGTTTTATGAGACCTTCTGAAAAATAATTTTTTAAAT
AAAAAATTTTCT

protein sequence of SMED30009282-orf-1

>SMED30009282-orf-1 ID=SMED30009282-orf-1|Name=SMED30009282-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=171bp
MDNVDKTDGNKEKDSIDVLILEIHDKINAAFEIFDHENNKSVDVREVGTI
IRSLGCCPSEAELHDILSEMEKPEPTGVVAYEDFLPLMSKILLEKRYKPR
HEDELLKAFQALDVEDKGFLTEDQLKKYLMEEGEVFNQDEIEEMLSKAIE
PETGKINYKSFVSELVIDDS*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000016	pharynx
PLANA:0000099	neuron
PLANA:0000418	head

Vocabulary: **INTERPRO**
Term	Definition
IPR011992	EF-hand-dom_pair
IPR014837	EF-hand_Ca_insen
IPR002048	EF_hand_dom

Vocabulary: **molecular function**
Term	Definition
GO:0005509	calcium ion binding

Vocabulary: **cellular component**
Term	Definition
GO:0005575	cellular_component

Vocabulary: **biological process**
Term	Definition
GO:0008150	biological_process

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR014837	EF-hand, Ca insensitive	PFAM	PF08726	EFhand_Ca_insen	coord: 102..165 e-value: 5.7E-5 score: 23.1
None	No IPR available	GENE3D	G3DSA:1.10.238.10		coord: 22..97 e-value: 3.9E-16 score: 61.1
None	No IPR available	GENE3D	G3DSA:1.10.238.10		coord: 100..163 e-value: 1.3E-12 score: 49.6
None	No IPR available	PANTHER	PTHR46763	FAMILY NOT NAMED	coord: 11..169
IPR002048	EF-hand domain	PROSITE	PS50222	EF_HAND_2	coord: 22..57 score: 8.209
IPR002048	EF-hand domain	PROSITE	PS50222	EF_HAND_2	coord: 100..135 score: 10.134
IPR011992	EF-hand domain pair	SUPERFAMILY	SSF47473	EF-hand	coord: 26..164