coiled-coil domain-containing protein 157 isoform X2

Overview
Namecoiled-coil domain-containing protein 157 isoform X2
Smed IDSMED30009257
Length (bp)2292
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of coiled-coil domain-containing protein 157 isoform X2 (SMED30009257) t-SNE clustered cells

Violin plots show distribution of expression levels for coiled-coil domain-containing protein 157 isoform X2 (SMED30009257) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of coiled-coil domain-containing protein 157 isoform X2 (SMED30009257) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for coiled-coil domain-containing protein 157 isoform X2 (SMED30009257) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30009257

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 4

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
head regionSMED30009257SMESG000042794.1 SmedASXL_012325SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016		whole organism asexual adult RNA-sequencing evidence
nervous systemSMED30009257SMESG000042794.1 dd_Smed_v4_10757_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
head regionSMED30009257SMESG000042794.1 dd_Smed_v6_10757_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017		whole organism asexual adult RNA-sequencing evidence
epidermisSMED30009257SMESG000042794.1 dd_Smed_v4_10757_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017		whole organism asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of coiled-coil domain-containing protein 157 isoform X2 vs. Ensembl Human
Match: CCDC157 (coiled-coil domain containing 157 [Source:HGNC Symbol;Acc:HGNC:33854])

HSP 1 Score: 132.494 bits (332), Expect = 9.889e-33
Identity = 138/596 (23.15%), Postives = 270/596 (45.30%), Query Frame = 1 
Query:   34 MSFLLGSEYCIQSLSNDVSDVQSCIKDIIFKVGRINSISWKFPDKFACDLNIDEYLTNYKYNPNDSESNQISHIILLELIIDRVCLLLQLHCETIEKIVSKDKLSNTNCKSDSKTKMMSPCL--GLTSKKHWNKLCQLSIYIDNIQQEIGQXXXXXXXXXXXXXXXXXXXMNENAAEEVGTNDNISKQAGDWLRTLENENKVNINKRKPVVG---------SIS-------KDMTFKS-----SQTVDTAFKPCESCHISQTCLRESSSILMKVLKQESQPSSLMKLQHEI---LNLDWLSDKKIMQIKDCFAKDLDKVCAIYQNIKQKEIKTVTELSDCRNMCKNFTEALEKEKCEMLASETKFSRQIHEFGVENEKLTNTISQLKLQTASLMEEIELKDKQINQDRAQLKQHILEKQNINEELDKLKVSISNFNVNATDPFEALAIIKRKISDLTDNISQL---NSTIQNQKSINENLTLTENVIKNKEEKLVKRLQSLTEQKHKLEEKIDILQDQVESNQESIRALENERNSMSMKLSNQTILIETITKAKDEFRVRITELQSQLEGMQQTILEINQGKDLLVNYPDLNGPLD 1734
            M+ LLGS+ C++SL  D++D+Q  I D+  + G +   SWKFPD+ ACDL++   L +Y + P D E  Q+SH +LLEL+IDR+ LLLQ     +E + S+  +           +   PC+  GLT ++ W+ L +L       QQ + Q                          E  T+   +K  G+  R+ E      I    PV+G         SI           TFK+     SQT++TA  PC++C   Q  L++   +++ + + ++ PSSL + Q  +   + L  L    + +      KDL ++    + ++ +  +   +    R       +AL++E+        +  + + E+  + ++L    S LK + A+L       ++++ Q R   +    + Q + EE ++   +            +  A ++  +  L     Q+   ++ +  +K+  +++   +  ++ K+  L+K+L SL +++ +L   +D  + Q    +E    L++ER     +L  Q  L++++ + K       T+L+  +  +++ + E+ + + LLV +PDL+ P +
Sbjct:    1 MAHLLGSQACMESLRTDLTDLQGAIVDVFSRAGPVRFPSWKFPDRMACDLDMVALLEHYDHVPGDPEFTQLSHAVLLELVIDRLLLLLQSCMSYLENLGSEQMM--------PPAQAAGPCMSVGLTVRRFWDSLLRLGTL---HQQPLPQKGANQ--------------------RETPTSKPTTK--GEPARSPEYLTTKLIKPSSPVLGLPQTCQEPESIPVRASLQFPATTFKNTRSVHSQTIETALVPCDACASVQGSLQKVGKVVISLCQSQNLPSSLGQFQQLVQDSMGLRPLPAATVGRWAAEQRKDLTRLSKHVEALRAQLEEAEGQKDGLRKQAGKLEQALKQEQGARRRQAEEDEQCLSEWEHDKQQLLTETSDLKTKMATL-------ERELKQQRESTQAVEAKAQQLQEEGERRAAAERQVQQLEEQVQQLEAQVQLLVGRLEGAGQQVCWASTELDKEKARVDSMVRHQESLQAKQRALLKQLDSLDQEREELRGSLDEAEAQRARVEEQ---LQSEREQGQCQLRAQQELLQSLQREKQGLEQATTDLRLTILELERELEELKERERLLVAFPDLHRPTE 553

HSP 2 Score: 29.261 bits (64), Expect = 9.889e-33
Identity = 14/39 (35.90%), Postives = 23/39 (58.97%), Query Frame = 3 
Query: 1812 SGNIEQDLINQIKSNAARISLLSEQNRDLEQALEKLNQT 1928
            SGN+   +  Q++SN  RI +L E+N  L+  L K+ + 
Sbjct:  574 SGNVTDHMERQVQSNDIRIRVLQEENGRLQSMLSKIREV 612
[Close]
BLAST of coiled-coil domain-containing protein 157 isoform X2 vs. Ensembl Human
Match: CCDC157 (coiled-coil domain containing 157 [Source:HGNC Symbol;Acc:HGNC:33854])

HSP 1 Score: 132.494 bits (332), Expect = 9.889e-33
Identity = 138/596 (23.15%), Postives = 270/596 (45.30%), Query Frame = 1 
Query:   34 MSFLLGSEYCIQSLSNDVSDVQSCIKDIIFKVGRINSISWKFPDKFACDLNIDEYLTNYKYNPNDSESNQISHIILLELIIDRVCLLLQLHCETIEKIVSKDKLSNTNCKSDSKTKMMSPCL--GLTSKKHWNKLCQLSIYIDNIQQEIGQXXXXXXXXXXXXXXXXXXXMNENAAEEVGTNDNISKQAGDWLRTLENENKVNINKRKPVVG---------SIS-------KDMTFKS-----SQTVDTAFKPCESCHISQTCLRESSSILMKVLKQESQPSSLMKLQHEI---LNLDWLSDKKIMQIKDCFAKDLDKVCAIYQNIKQKEIKTVTELSDCRNMCKNFTEALEKEKCEMLASETKFSRQIHEFGVENEKLTNTISQLKLQTASLMEEIELKDKQINQDRAQLKQHILEKQNINEELDKLKVSISNFNVNATDPFEALAIIKRKISDLTDNISQL---NSTIQNQKSINENLTLTENVIKNKEEKLVKRLQSLTEQKHKLEEKIDILQDQVESNQESIRALENERNSMSMKLSNQTILIETITKAKDEFRVRITELQSQLEGMQQTILEINQGKDLLVNYPDLNGPLD 1734
            M+ LLGS+ C++SL  D++D+Q  I D+  + G +   SWKFPD+ ACDL++   L +Y + P D E  Q+SH +LLEL+IDR+ LLLQ     +E + S+  +           +   PC+  GLT ++ W+ L +L       QQ + Q                          E  T+   +K  G+  R+ E      I    PV+G         SI           TFK+     SQT++TA  PC++C   Q  L++   +++ + + ++ PSSL + Q  +   + L  L    + +      KDL ++    + ++ +  +   +    R       +AL++E+        +  + + E+  + ++L    S LK + A+L       ++++ Q R   +    + Q + EE ++   +            +  A ++  +  L     Q+   ++ +  +K+  +++   +  ++ K+  L+K+L SL +++ +L   +D  + Q    +E    L++ER     +L  Q  L++++ + K       T+L+  +  +++ + E+ + + LLV +PDL+ P +
Sbjct:    1 MAHLLGSQACMESLRTDLTDLQGAIVDVFSRAGPVRFPSWKFPDRMACDLDMVALLEHYDHVPGDPEFTQLSHAVLLELVIDRLLLLLQSCMSYLENLGSEQMM--------PPAQAAGPCMSVGLTVRRFWDSLLRLGTL---HQQPLPQKGANQ--------------------RETPTSKPTTK--GEPARSPEYLTTKLIKPSSPVLGLPQTCQEPESIPVRASLQFPATTFKNTRSVHSQTIETALVPCDACASVQGSLQKVGKVVISLCQSQNLPSSLGQFQQLVQDSMGLRPLPAATVGRWAAEQRKDLTRLSKHVEALRAQLEEAEGQKDGLRKQAGKLEQALKQEQGARRRQAEEDEQCLSEWEHDKQQLLTETSDLKTKMATL-------ERELKQQRESTQAVEAKAQQLQEEGERRAAAERQVQQLEEQVQQLEAQVQLLVGRLEGAGQQVCWASTELDKEKARVDSMVRHQESLQAKQRALLKQLDSLDQEREELRGSLDEAEAQRARVEEQ---LQSEREQGQCQLRAQQELLQSLQREKQGLEQATTDLRLTILELERELEELKERERLLVAFPDLHRPTE 553

HSP 2 Score: 29.261 bits (64), Expect = 9.889e-33
Identity = 14/39 (35.90%), Postives = 23/39 (58.97%), Query Frame = 3 
Query: 1812 SGNIEQDLINQIKSNAARISLLSEQNRDLEQALEKLNQT 1928
            SGN+   +  Q++SN  RI +L E+N  L+  L K+ + 
Sbjct:  574 SGNVTDHMERQVQSNDIRIRVLQEENGRLQSMLSKIREV 612
[Close]
BLAST of coiled-coil domain-containing protein 157 isoform X2 vs. Ensembl Human
Match: CCDC157 (coiled-coil domain containing 157 [Source:HGNC Symbol;Acc:HGNC:33854])

HSP 1 Score: 106.301 bits (264), Expect = 1.421e-25
Identity = 53/139 (38.13%), Postives = 81/139 (58.27%), Query Frame = 1 
Query:   34 MSFLLGSEYCIQSLSNDVSDVQSCIKDIIFKVGRINSISWKFPDKFACDLNIDEYLTNYKYNPNDSESNQISHIILLELIIDRVCLLLQLHCETIEKIVSKDKLSNTNCKSDSKTKMMSPCL--GLTSKKHWNKLCQLS 444
            M+ LLGS+ C++SL  D++D+Q  I D+  + G +   SWKFPD+ ACDL++   L +Y + P D E  Q+SH +LLEL+IDR+ LLLQ     +E + S+  +               PC+  GLT ++ W+ L +L 
Sbjct:    1 MAHLLGSQACMESLRTDLTDLQGAIVDVFSRAGPVRFPSWKFPDRMACDLDMVALLEHYDHVPGDPEFTQLSHAVLLELVIDRLLLLLQSCMSYLENLGSEQMMPPAQAA--------GPCMSVGLTVRRFWDSLLRLG 131
[Close]
BLAST of coiled-coil domain-containing protein 157 isoform X2 vs. Ensembl Human
Match: CCDC157 (coiled-coil domain containing 157 [Source:HGNC Symbol;Acc:HGNC:33854])

HSP 1 Score: 106.301 bits (264), Expect = 1.619e-25
Identity = 53/139 (38.13%), Postives = 81/139 (58.27%), Query Frame = 1 
Query:   34 MSFLLGSEYCIQSLSNDVSDVQSCIKDIIFKVGRINSISWKFPDKFACDLNIDEYLTNYKYNPNDSESNQISHIILLELIIDRVCLLLQLHCETIEKIVSKDKLSNTNCKSDSKTKMMSPCL--GLTSKKHWNKLCQLS 444
            M+ LLGS+ C++SL  D++D+Q  I D+  + G +   SWKFPD+ ACDL++   L +Y + P D E  Q+SH +LLEL+IDR+ LLLQ     +E + S+  +               PC+  GLT ++ W+ L +L 
Sbjct:    1 MAHLLGSQACMESLRTDLTDLQGAIVDVFSRAGPVRFPSWKFPDRMACDLDMVALLEHYDHVPGDPEFTQLSHAVLLELVIDRLLLLLQSCMSYLENLGSEQMMPPAQAA--------GPCMSVGLTVRRFWDSLLRLG 131
[Close]
BLAST of coiled-coil domain-containing protein 157 isoform X2 vs. Ensembl Human
Match: CCDC157 (coiled-coil domain containing 157 [Source:HGNC Symbol;Acc:HGNC:33854])

HSP 1 Score: 91.2781 bits (225), Expect = 1.163e-21
Identity = 39/83 (46.99%), Postives = 57/83 (68.67%), Query Frame = 1 
Query:   34 MSFLLGSEYCIQSLSNDVSDVQSCIKDIIFKVGRINSISWKFPDKFACDLNIDEYLTNYKYNPNDSESNQISHIILLELIIDR 282
            M+ LLGS+ C++SL  D++D+Q  I D+  + G +   SWKFPD+ ACDL++   L +Y + P D E  Q+SH +LLEL+IDR
Sbjct:    1 MAHLLGSQACMESLRTDLTDLQGAIVDVFSRAGPVRFPSWKFPDRMACDLDMVALLEHYDHVPGDPEFTQLSHAVLLELVIDR 83
[Close]
BLAST of coiled-coil domain-containing protein 157 isoform X2 vs. Ensembl Zebrafish
Match: ccdc157 (coiled-coil domain containing 157 [Source:ZFIN;Acc:ZDB-GENE-030616-155])

HSP 1 Score: 99.7525 bits (247), Expect = 3.948e-21
Identity = 141/585 (24.10%), Postives = 266/585 (45.47%), Query Frame = 1 
Query:   34 MSFLLGSEYCIQSLSNDVSDVQSCIKDIIFKVGRINSISWKFPDKFACDLNIDEYLTNYKYNPNDSESNQISHIILLELIIDRVCLLLQLHCETIEKIVSKDKLSNTNCKSDSKTKMMSPCLGLTSKKHWNKLCQLSIYIDNIQQEIGQXXXXXXXXXXXXXXXXXXXMNENAAEEVGTNDNISKQAGDWLRTLENENK-----VNINKRKPVV----GSISKDMTFKSSQTVDTAFKPCESCHISQTCLRESSSILMKVLKQESQPSSL---MKLQHEILNLDWLSDKKIMQIKDCFAKDLDKVCA-------IYQNIKQKEIKTVTELSDCRNMCKNFTEALEKEKCEMLASETKFSRQIHEFGVENEKLTNTISQLKLQTASLMEEIELKDKQINQDRAQLKQHILEKQNINEELDKLKVSISNFNVNATDPFEALAIIKRKISDLTDNISQLNSTIQNQKSINENLTLTENVIKNKEEKLVKRLQSLTEQKHKLEEKIDILQDQVESNQESIRALENERNSMSMKLSNQTILIETITKAKDEFRVRITELQ---SQLEGMQQTILEINQGKDLLVNYPDLN 1722
            MS LLG + CI SL  D+ D+Q  + D+  K G +   SWKFPDK +C+L++   L  Y Y  +D E +Q SHI+L EL+IDR+ LLLQ      E ++ K +  + +    S +      +G   K++W  L QL     N QQ+                   +   N+  +++   + ++SK A +   TL+ ++         +   P      GS     +  S QTV++A  PCE+C   Q  L+E+S  ++ + +    P S+   ++   E   L  LS   I Q      +D+ +V           + +K+K  +T  E    R   K  +E + +EK E    + ++ R++ E  V++E   + + +LK +   L   + L + + ++   +LK     K ++  E + L+  +   +   T     L  ++    +L   +    + +  ++  N ++      ++ K+  L K L  L +Q  +L   ++  +D+       ++ +  E++++  +L++Q     ++    +  + +ITEL+   S+LEGM   + E  Q + LLV +P+L+
Sbjct:    1 MSHLLGRQDCIDSLRRDLIDLQGALLDVFSKTGPVRFPSWKFPDKLSCNLDLVRLLEEYDYVEDDEEFSQHSHIVLQELLIDRLMLLLQSFNVHAELLLEKQQTLSLDPNETSVS------IGPVVKRYWKNLLQL-----NSQQK----------------QESSCSGNQPPSQQ---SPSVSKTAPNTPTTLKTQSASMSSIHKTSSSSPAFTLQHGSCVSTHSV-SCQTVESALVPCEACACVQAVLKENSDAVVSLCQSLGLPCSMQGFLEAVEETQQLGRLSACDISQWASEQRRDMSRVGKHVLEVRETVEPLKRKVKETEMEREKLR---KQLSETVNREKEERRKMDEQWERKMQEVKVKSE---DAVRRLKQEQEELKRGLTLLEDRNSELTVELKLQTEAKHSLEFERNGLQEEVHRLHSFET----MLKEVEESRQNLEKELRSTQTLLDKERGRNHSVQHQHEALQVKQTALRKHLDVLVQQTEELHSSLEECEDEKADLGNKLKQIMREKDTLQEQLTHQQSQNSSLCTEIESQQTQITELEERVSRLEGM---LEEAVQRERLLVAFPELS 541
[Close]
BLAST of coiled-coil domain-containing protein 157 isoform X2 vs. Ensembl Zebrafish
Match: ccdc157 (coiled-coil domain containing 157 [Source:ZFIN;Acc:ZDB-GENE-030616-155])

HSP 1 Score: 83.9593 bits (206), Expect = 2.255e-16
Identity = 113/419 (26.97%), Postives = 188/419 (44.87%), Query Frame = 1 
Query:   34 MSFLLGSEYCIQSLSNDVSDVQSCIKDIIFKVGRINSISWKFPDKFACDLNIDEYLTNYKYNPNDSESNQISHIILLELIIDRVCLLLQLHCETIEKIVSKDKLSNTNCKSDSKTKMMSPCLGLTSKKHWNKLCQLSIYIDNIQQEIGQXXXXXXXXXXXXXXXXXXXMNENAAEEVGTNDNISKQAGDWLRTLENENK-----VNINKRKPVV----GSISKDMTFKSSQTVDTAFKPCESCHISQTCLRESSSILMKVLKQESQPSSL---MKLQHEILNLDWLSDKKIMQIKDCFAKDLDKVCA-------IYQNIKQKEIKTVTELSDCRNMCKNFTEALEKEKCEMLASETKFSRQIHE-FGVENEKLTNTISQLKLQTASLMEEIELKDKQINQDRAQLKQHILEKQNINEEL 1230
            MS LLG + CI SL  D+ D+Q  + D+  K G +   SWKFPDK +C+L++   L  Y Y  +D E +Q SHI+L EL+IDR+ LLLQ      E ++ K +  + +    S +      +G   K++W  L QL     N QQ+                   +   N+  +++   + ++SK A +   TL+ ++         +   P      GS     +  S QTV++A  PCE+C   Q  L+E+S  ++ + +    P S+   ++   E   L  LS   I Q      +D+ +V           + +K+K  +T  E    R   K  +E + +EK E    + ++ R++ E   V+   L   +  L  QT  L   +E  + +      +LKQ + EK  + E+L
Sbjct:    1 MSHLLGRQDCIDSLRRDLIDLQGALLDVFSKTGPVRFPSWKFPDKLSCNLDLVRLLEEYDYVEDDEEFSQHSHIVLQELLIDRLMLLLQSFNVHAELLLEKQQTLSLDPNETSVS------IGPVVKRYWKNLLQL-----NSQQK----------------QESSCSGNQPPSQQ---SPSVSKTAPNTPTTLKTQSASMSSIHKTSSSSPAFTLQHGSCVSTHSV-SCQTVESALVPCEACACVQAVLKENSDAVVSLCQSLGLPCSMQGFLEAVEETQQLGRLSACDISQWASEQRRDMSRVGKHVLEVRETVEPLKRKVKETEMEREKLR---KQLSETVNREKEERRKMDEQWERKMQEALQVKQTALRKHLDVLVQQTEELHSSLEECEDEKADLGNKLKQIMREKDTLQEQL 385
[Close]
BLAST of coiled-coil domain-containing protein 157 isoform X2 vs. Ensembl Xenopus
Match: tlx1 (T cell leukemia homeobox 1 [Source:Xenbase;Acc:XB-GENE-485834])

HSP 1 Score: 92.0485 bits (227), Expect = 1.605e-21
Identity = 39/83 (46.99%), Postives = 58/83 (69.88%), Query Frame = 1 
Query:   34 MSFLLGSEYCIQSLSNDVSDVQSCIKDIIFKVGRINSISWKFPDKFACDLNIDEYLTNYKYNPNDSESNQISHIILLELIIDR 282
            M+ LLG   C++SL  D++D+Q  + D+  +VG +   SWKFPDK +CDL++ + +  Y Y  +DSE  Q+SH++LLELIIDR
Sbjct:   39 MTNLLGDRTCMESLRKDITDLQGTLIDVFSRVGAVRYPSWKFPDKMSCDLDLVDLMERYDYVESDSEYTQLSHVVLLELIIDR 121
[Close]
BLAST of coiled-coil domain-containing protein 157 isoform X2 vs. Ensembl Xenopus
Match: ENSXETT00000018529.1 (coiled-coil domain containing 157 [Source:NCBI gene;Acc:100494973])

HSP 1 Score: 59.3066 bits (142), Expect = 9.709e-12
Identity = 89/373 (23.86%), Postives = 178/373 (47.72%), Query Frame = 1 
Query:  691 SSQTVDTAFKPCESCHISQTCLRESSSILMKVLKQESQPSSLMKLQHEILNLDWLSDKKIMQIKDCFAKDLDKVCAIYQNIKQK--EIKTVTELSDCRNM--------CKNFTEALEKEKCEMLASETKFSRQIHEFGVENEKLTNTI----SQLKLQTASLMEEI-----ELKDKQINQDRAQLKQHILEKQNINEELDKLKVSISNFNVNATDPFEALAIIKRKISDLTDNI-SQLNSTIQNQKSINENLTLTENVIKNKEEKLVKRLQSLTEQKHKLEEKIDILQDQVESNQE-------SIRALENERNSMSMKLSNQTILIETITKAKDEFRVRITELQSQLEGMQQTILEINQGKDLLVNYPDLNGP 1728
            SSQTV+++  PC+SC I+Q  L E S+ ++ V   ++ P SL K++  +     LS  ++       +KDL ++      +KQ+   +K   E     N         CKN    L+++K E      ++ R++ E   +N+++ + +     +LK  + +L E I     ELKD           QHI  +     +L++ +  + +      +  E ++++ +K+SDL  ++ S LN    +++++++    +E+ ++N +E L  + +SL +Q  +L ++ + LQ  V   +E        I  +E ER  +  +L  Q  +++ + + K       + L  QL  ++Q++ E  + + LL  YP+L  P
Sbjct:   94 SSQTVESSLVPCDSCAIAQRSLYEVSNAIINVCTGQNLPCSLSKIRDMLPLGRILSPTEMRYWASEESKDLARIGKYLSELKQEICPLKDQLEAGKADNEKLQKSIENCKN---QLQEQKEEQRRQAKQYERKLQEKRQQNQEVVDKLERDKQELKKGSLALEERISCLKEELKD-----------QHITIR-----DLERARKELVDEMCGMVNKAE-VSMLVQKMSDLKSDLKSTLNKLQDSEEAMSKERARSES-LQNHKESLHMKQRSLLQQLDRLAQENEDLQGTVGEAEEEKAKLVDQIADIERERKVLRSQLQEQQEIVKVLQQEKQILEESASSLDRQLVELKQSLQEQREREKLLALYPELQPP 445

HSP 2 Score: 31.5722 bits (70), Expect = 9.709e-12
Identity = 21/87 (24.14%), Postives = 47/87 (54.02%), Query Frame = 3 
Query: 1812 SGNIEQDLINQIKSNAARISLLSEQNRDLEQALEKLNQ-TYXXXXXXXXXXXVKATNNLSNTSGLPPNVASLELSRPHSKMSHVGQS 2069
            +G++ QD+  Q+++N  RI++L E+N  L   L KL + ++     ++  + + +  +++ ++GL P     + +RP   +    QS
Sbjct:  451 TGDVTQDMEKQLQANNLRITILEEENSRLRATLCKLREKSHQEPLRLVPQTQLWSIPHVTESAGLEPRHEVSKKARPQLNLRDTSQS 537
[Close]
BLAST of coiled-coil domain-containing protein 157 isoform X2 vs. Ensembl Mouse
Match: Ccdc157 (coiled-coil domain containing 157 [Source:MGI Symbol;Acc:MGI:3041210])

HSP 1 Score: 129.028 bits (323), Expect = 1.353e-33
Identity = 143/600 (23.83%), Postives = 268/600 (44.67%), Query Frame = 1 
Query:   34 MSFLLGSEYCIQSLSNDVSDVQSCIKDIIFKVGRINSISWKFPDKFACDLNIDEYLTNYKYNPNDSESNQISHIILLELIIDRVCLLLQLHCETIEKIVSKDKLSNTNCKSDSKTKMMSPCL--GLTSKKHWNKLCQLSIYIDNIQQEIGQXXXXXXXXXXXXXXXXXXXMNENAAEEVGTNDNISKQAGDWLRTLENENKVNINKRKPVVG---------SISKDMTFKS------------SQTVDTAFKPCESCHISQTCLRESSSILMKVLKQESQPSSLMKLQHEI---LNLDWLSDKKIMQIKDCFAKDLDKVCAIYQNIKQKEIKTVTELSDC-------RNMCKNFTEALEKEKCEMLASETKFSRQIHEFGVENEKLTNTISQLKLQTASLMEEIELKDKQIN--QDRAQLKQHILEKQNINEELDKLKVSISNFNVNATDPFEALAIIKRKISDLTDNISQLNSTIQNQKSINENLTLTENVIKNKEEKLVKRLQSLTEQKHKLEEKIDILQDQVESNQESIRALENERNSMSMKLSNQTILIETITKAKDEFRVRITELQSQLEGMQQTILEINQGKDLLVNYPDLNGP 1728
            M+ LLGS+ C+ SL  D++D+Q  I D+  + G +   SWKFPD+ ACDL++   L +Y + P D E  Q+SH +LLEL+IDR+ LLLQ     +E +  +  +           +   PC+  GLT ++ W+ L +L +     QQ + Q                  + N+    E+      +K  G+  R+ E      I    PV G         SI   ++ +S            SQTV+TA  PC++C   Q  L E   +++ + + ++ PSSL + Q  +   L L  L    +       +KDL ++      + Q       +L D        R       +AL++E+ +      +  R + +   +  +L      LK + A L  +++ + K I   + +AQ  +   E++   E   +             D   A   I+   ++L    ++++S +++Q+S           ++ K+  L+++L  L +++ +L   +D  + Q    +E +++L+++R     +L  Q  L++++ + K +     T+LQ  +  ++Q + E+ + + LLV +PDL+ P
Sbjct:    1 MAHLLGSQACMDSLRKDLTDLQGTIVDVFSRAGPVRFPSWKFPDRVACDLDMVALLEHYDHVPGDPEFTQLSHAVLLELVIDRLLLLLQSCASYLENLSVEQMM--------PPARAAGPCMSVGLTVRRFWSNLLRLGLL---YQQAVPQ-----------------KRANQG---EISITKPTAK--GEPARSPECMTAKFIKPPSPVPGLPLICQGLQSIPVRVSLRSPGGTSEKTKSVYSQTVETALVPCDACTSVQGSLWEVGKVVISLCQSQNLPSSLGQFQKLVKDSLGLKPLPAATVGHWAAEQSKDLTRLNKHVGALTQLVGPLRAQLEDAEGQKDGLRKQVSKLEQALQQEQGQRQRQTEEAERTLAKCEHDRHQLLTETCDLKTKVAVLEGDLKQQQKSIQAMEAKAQQLEEEGERRAAAERQVQQLEEQVQLLAGRLD--GASQQIRWASTELDKEKARVDSMVRHQES-----------LQAKQRTLLQQLDCLDQEREELRGSLDEAEAQRSELEEQLQSLQSDREQEQCQLQAQQELLQSLQQEKQDLEQVTTDLQLTISELRQQLEELKERERLLVAFPDLHQP 554

HSP 2 Score: 35.039 bits (79), Expect = 1.353e-33
Identity = 16/43 (37.21%), Postives = 28/43 (65.12%), Query Frame = 3 
Query: 1800 KI*KSGNIEQDLINQIKSNAARISLLSEQNRDLEQALEKLNQT 1928
            +I  S N+ QD+  Q+++NA RI +L E+N+ L+  L K+ + 
Sbjct:  558 QIQSSSNVTQDMERQVQANAIRIQVLQEENKRLQSMLTKIREV 600
[Close]
BLAST of coiled-coil domain-containing protein 157 isoform X2 vs. Ensembl Mouse
Match: Ccdc157 (coiled-coil domain containing 157 [Source:MGI Symbol;Acc:MGI:3041210])

HSP 1 Score: 45.4394 bits (106), Expect = 9.180e-9
Identity = 80/378 (21.16%), Postives = 169/378 (44.71%), Query Frame = 1 
Query:  631 VNINKRKPVVGSISKDMTFKSSQTVDTAFKPCESCHISQTCLRESSSILMKVLKQESQPSSLMKLQHEI---LNLDWLSDKKIMQIKDCFAKDLDKVCAIYQNIKQKEIKTVTELSDC-------RNMCKNFTEALEKEKCEMLASETKFSRQIHEFGVENEKLTNTISQLKLQTASLMEEIELKDKQIN--QDRAQLKQHILEKQNINEELDKLKVSISNFNVNATDPFEALAIIKRKISDLTDNISQLNSTIQNQKSINENLTLTENVIKNKEEKLVKRLQSLTEQKHKLEEKIDILQDQVESNQESIRALENERNSMSMKLSNQTILIETITKAKDEFRVRITELQSQLEGMQQTILEINQGKDLLVNYPDLNGP 1728
            V ++ R P  G  S+      SQTV+TA  PC++C   Q  L E   +++ + + ++ PSSL + Q  +   L L  L    +       +KDL ++      + Q       +L D        R       +AL++E+ +      +  R + +   +  +L      LK + A L  +++ + K I   + +AQ  +   E++   E   +             D   A   I+   ++L    ++++S +++Q+S+           + K+  L+++L  L +++ +L   +D  + Q    +E +++L+++R     +L  Q  L++++ + K +     T+LQ  +  ++Q + E+ + + LLV +PDL+ P
Sbjct:   90 VRVSLRSP--GGTSEKTKSVYSQTVETALVPCDACTSVQGSLWEVGKVVISLCQSQNLPSSLGQFQKLVKDSLGLKPLPAATVGHWAAEQSKDLTRLNKHVGALTQLVGPLRAQLEDAEGQKDGLRKQVSKLEQALQQEQGQRQRQTEEAERTLAKCEHDRHQLLTETCDLKTKVAVLEGDLKQQQKSIQAMEAKAQQLEEEGERRAAAERQVQQLEEQVQLLAGRLD--GASQQIRWASTELDKEKARVDSMVRHQESL-----------QAKQRTLLQQLDCLDQEREELRGSLDEAEAQRSELEEQLQSLQSDREQEQCQLQAQQELLQSLQQEKQDLEQVTTDLQLTISELRQQLEELKERERLLVAFPDLHQP 452

HSP 2 Score: 35.039 bits (79), Expect = 9.180e-9
Identity = 16/43 (37.21%), Postives = 28/43 (65.12%), Query Frame = 3 
Query: 1800 KI*KSGNIEQDLINQIKSNAARISLLSEQNRDLEQALEKLNQT 1928
            +I  S N+ QD+  Q+++NA RI +L E+N+ L+  L K+ + 
Sbjct:  456 QIQSSSNVTQDMERQVQANAIRIQVLQEENKRLQSMLTKIREV 498
[Close]
BLAST of coiled-coil domain-containing protein 157 isoform X2 vs. UniProt/SwissProt
Match: sp|A4IFI1|CC157_BOVIN (Coiled-coil domain-containing protein 157 OS=Bos taurus OX=9913 GN=CCDC157 PE=2 SV=2)

HSP 1 Score: 144.821 bits (364), Expect = 3.775e-36
Identity = 150/597 (25.13%), Postives = 275/597 (46.06%), Query Frame = 1 
Query:   34 MSFLLGSEYCIQSLSNDVSDVQSCIKDIIFKVGRINSISWKFPDKFACDLNIDEYLTNYKYNPNDSESNQISHIILLELIIDRVCLLLQ-----LHCETIEKIVSKDKLSNTNCKSDSKTKMMSPCL--GLTSKKHWNKLCQLSIYIDNIQQEIGQXXXXXXXXXXXXXXXXXXXMNENAA-EEVGTNDNI---SKQAGDWLRTLENEN-KVNINKRKPVVGSISKDMTFKSSQTVDTAFKPCESCHISQTCLRESSSILMKVLKQESQPSSLMKLQ--------HEILNLDWLSDKKIMQIKD--CFAKDLDKVCAIYQNIKQKEIKTVTELSDCRNMCKNFTEALEKEKCEMLASETKFSRQIHEFGVENEKLTNTISQLKLQTASLMEEIELKDK----QINQDRAQLKQ----HILEKQNINEELDKLKVSISNFNVNATDPFEALAIIKRKISDLTDNISQLNSTIQNQKSINENLTLTENVIKNKEEKLVKRLQSLTEQKHKLEEKIDILQDQVESNQESIRALENERNSMSMKLSNQTILIETITKAKDEFRVRITELQSQLEGMQQTILEINQGKDLLVNYPDLNGPLD 1734
            M+ LLGS  C+ SL  D++D+Q  I D+  + G +   SWKFPD+ ACDL++   L +Y + P D E  Q++H +LLEL+IDR+ LLLQ     L   T+E+IV                +   PC+  GLT ++ WN L +L +          QA    +         K     E A   E+GT   +   S   G      E ++  V+++ R+P  G  +++     SQT++TA  PC++C   Q+ LRE   +++ + + ++ PSSL + Q        H  L    +      Q KD  C  K +  + A  +  + ++ +   ++ +     +    A +++  E      ++ R       E ++L    S LK + A+L  E ELK +    Q  + +AQ  Q    H LE +   + L++ +V +    ++      A   I+   ++L    ++++S +++Q+S           ++ K+  L+++L SL +++ +L   +D  + Q    +E +++++ ER                  +A  + R+ I+EL+ +L       +E+ + + LLV +PDL+ P +
Sbjct:    1 MAHLLGSPACMDSLRKDLTDLQGAIVDVFSRAGPVRFPSWKFPDRAACDLDMVALLEHYDHVPGDPEFTQLAHAVLLELVIDRLLLLLQSCASYLENLTLEQIV-------------PPARAAGPCMSVGLTVRRFWNSLLRLGMLSQ-------QAALQKRANQGETLTSKPTAKGEPAGSRELGTAQLVKPPSPVPGLPQACPERDSLPVSVSLRRP--GGTAENTRSVHSQTIETALVPCDACTSVQSSLREVGKVVINLCQSQNLPSSLGRFQQLVRDSMGHRPLPAATVGLWAAEQSKDLACLGKLVGLLRAQLEEAEGQKDRLRMQVGELEQALQEEQAARQRQAQEAEQHRAQWER-------ERQQLLAETSDLKTKVATL--EGELKQQRESTQAVESKAQQLQAEAEHRLEAERQVQHLEQ-QVELLAGRLDG-----ASQQIRWASTELDKEKARVDSMVRHQES-----------LQAKQRALLQQLDSLDQEREELRGSLDEAEAQRAHVEEQLQSVQGERE-----------------QATTDLRLTISELEREL-------VELRERERLLVAFPDLHRPAE 525

HSP 2 Score: 30.8018 bits (68), Expect = 3.775e-36
Identity = 15/43 (34.88%), Postives = 25/43 (58.14%), Query Frame = 3 
Query: 1800 KI*KSGNIEQDLINQIKSNAARISLLSEQNRDLEQALEKLNQT 1928
            +I  SGN+  D+  Q+++N  RI +L E+N  L   L K+ + 
Sbjct:  527 QIQSSGNVTDDMERQVQANDIRIRVLQEENGRLRSMLSKIREV 569
[Close]
BLAST of coiled-coil domain-containing protein 157 isoform X2 vs. UniProt/SwissProt
Match: sp|Q5SPX1|CC157_MOUSE (Coiled-coil domain-containing protein 157 OS=Mus musculus OX=10090 GN=Ccdc157 PE=1 SV=1)

HSP 1 Score: 129.028 bits (323), Expect = 8.228e-33
Identity = 143/600 (23.83%), Postives = 268/600 (44.67%), Query Frame = 1 
Query:   34 MSFLLGSEYCIQSLSNDVSDVQSCIKDIIFKVGRINSISWKFPDKFACDLNIDEYLTNYKYNPNDSESNQISHIILLELIIDRVCLLLQLHCETIEKIVSKDKLSNTNCKSDSKTKMMSPCL--GLTSKKHWNKLCQLSIYIDNIQQEIGQXXXXXXXXXXXXXXXXXXXMNENAAEEVGTNDNISKQAGDWLRTLENENKVNINKRKPVVG---------SISKDMTFKS------------SQTVDTAFKPCESCHISQTCLRESSSILMKVLKQESQPSSLMKLQHEI---LNLDWLSDKKIMQIKDCFAKDLDKVCAIYQNIKQKEIKTVTELSDC-------RNMCKNFTEALEKEKCEMLASETKFSRQIHEFGVENEKLTNTISQLKLQTASLMEEIELKDKQIN--QDRAQLKQHILEKQNINEELDKLKVSISNFNVNATDPFEALAIIKRKISDLTDNISQLNSTIQNQKSINENLTLTENVIKNKEEKLVKRLQSLTEQKHKLEEKIDILQDQVESNQESIRALENERNSMSMKLSNQTILIETITKAKDEFRVRITELQSQLEGMQQTILEINQGKDLLVNYPDLNGP 1728
            M+ LLGS+ C+ SL  D++D+Q  I D+  + G +   SWKFPD+ ACDL++   L +Y + P D E  Q+SH +LLEL+IDR+ LLLQ     +E +  +  +           +   PC+  GLT ++ W+ L +L +     QQ + Q                  + N+    E+      +K  G+  R+ E      I    PV G         SI   ++ +S            SQTV+TA  PC++C   Q  L E   +++ + + ++ PSSL + Q  +   L L  L    +       +KDL ++      + Q       +L D        R       +AL++E+ +      +  R + +   +  +L      LK + A L  +++ + K I   + +AQ  +   E++   E   +             D   A   I+   ++L    ++++S +++Q+S           ++ K+  L+++L  L +++ +L   +D  + Q    +E +++L+++R     +L  Q  L++++ + K +     T+LQ  +  ++Q + E+ + + LLV +PDL+ P
Sbjct:    1 MAHLLGSQACMDSLRKDLTDLQGTIVDVFSRAGPVRFPSWKFPDRVACDLDMVALLEHYDHVPGDPEFTQLSHAVLLELVIDRLLLLLQSCASYLENLSVEQMM--------PPARAAGPCMSVGLTVRRFWSNLLRLGLL---YQQAVPQ-----------------KRANQG---EISITKPTAK--GEPARSPECMTAKFIKPPSPVPGLPLICQGLQSIPVRVSLRSPGGTSEKTKSVYSQTVETALVPCDACTSVQGSLWEVGKVVISLCQSQNLPSSLGQFQKLVKDSLGLKPLPAATVGHWAAEQSKDLTRLNKHVGALTQLVGPLRAQLEDAEGQKDGLRKQVSKLEQALQQEQGQRQRQTEEAERTLAKCEHDRHQLLTETCDLKTKVAVLEGDLKQQQKSIQAMEAKAQQLEEEGERRAAAERQVQQLEEQVQLLAGRLD--GASQQIRWASTELDKEKARVDSMVRHQES-----------LQAKQRTLLQQLDCLDQEREELRGSLDEAEAQRSELEEQLQSLQSDREQEQCQLQAQQELLQSLQQEKQDLEQVTTDLQLTISELRQQLEELKERERLLVAFPDLHQP 554

HSP 2 Score: 35.039 bits (79), Expect = 8.228e-33
Identity = 16/43 (37.21%), Postives = 28/43 (65.12%), Query Frame = 3 
Query: 1800 KI*KSGNIEQDLINQIKSNAARISLLSEQNRDLEQALEKLNQT 1928
            +I  S N+ QD+  Q+++NA RI +L E+N+ L+  L K+ + 
Sbjct:  558 QIQSSSNVTQDMERQVQANAIRIQVLQEENKRLQSMLTKIREV 600
[Close]
BLAST of coiled-coil domain-containing protein 157 isoform X2 vs. UniProt/SwissProt
Match: sp|Q569K6|CC157_HUMAN (Coiled-coil domain-containing protein 157 OS=Homo sapiens OX=9606 GN=CCDC157 PE=1 SV=3)

HSP 1 Score: 132.494 bits (332), Expect = 4.355e-32
Identity = 138/596 (23.15%), Postives = 270/596 (45.30%), Query Frame = 1 
Query:   34 MSFLLGSEYCIQSLSNDVSDVQSCIKDIIFKVGRINSISWKFPDKFACDLNIDEYLTNYKYNPNDSESNQISHIILLELIIDRVCLLLQLHCETIEKIVSKDKLSNTNCKSDSKTKMMSPCL--GLTSKKHWNKLCQLSIYIDNIQQEIGQXXXXXXXXXXXXXXXXXXXMNENAAEEVGTNDNISKQAGDWLRTLENENKVNINKRKPVVG---------SIS-------KDMTFKS-----SQTVDTAFKPCESCHISQTCLRESSSILMKVLKQESQPSSLMKLQHEI---LNLDWLSDKKIMQIKDCFAKDLDKVCAIYQNIKQKEIKTVTELSDCRNMCKNFTEALEKEKCEMLASETKFSRQIHEFGVENEKLTNTISQLKLQTASLMEEIELKDKQINQDRAQLKQHILEKQNINEELDKLKVSISNFNVNATDPFEALAIIKRKISDLTDNISQL---NSTIQNQKSINENLTLTENVIKNKEEKLVKRLQSLTEQKHKLEEKIDILQDQVESNQESIRALENERNSMSMKLSNQTILIETITKAKDEFRVRITELQSQLEGMQQTILEINQGKDLLVNYPDLNGPLD 1734
            M+ LLGS+ C++SL  D++D+Q  I D+  + G +   SWKFPD+ ACDL++   L +Y + P D E  Q+SH +LLEL+IDR+ LLLQ     +E + S+  +           +   PC+  GLT ++ W+ L +L       QQ + Q                          E  T+   +K  G+  R+ E      I    PV+G         SI           TFK+     SQT++TA  PC++C   Q  L++   +++ + + ++ PSSL + Q  +   + L  L    + +      KDL ++    + ++ +  +   +    R       +AL++E+        +  + + E+  + ++L    S LK + A+L       ++++ Q R   +    + Q + EE ++   +            +  A ++  +  L     Q+   ++ +  +K+  +++   +  ++ K+  L+K+L SL +++ +L   +D  + Q    +E    L++ER     +L  Q  L++++ + K       T+L+  +  +++ + E+ + + LLV +PDL+ P +
Sbjct:    1 MAHLLGSQACMESLRTDLTDLQGAIVDVFSRAGPVRFPSWKFPDRMACDLDMVALLEHYDHVPGDPEFTQLSHAVLLELVIDRLLLLLQSCMSYLENLGSEQMM--------PPAQAAGPCMSVGLTVRRFWDSLLRLGTL---HQQPLPQKGANQ--------------------RETPTSKPTTK--GEPARSPEYLTTKLIKPSSPVLGLPQTCQEPESIPVRASLQFPATTFKNTRSVHSQTIETALVPCDACASVQGSLQKVGKVVISLCQSQNLPSSLGQFQQLVQDSMGLRPLPAATVGRWAAEQRKDLTRLSKHVEALRAQLEEAEGQKDGLRKQAGKLEQALKQEQGARRRQAEEDEQCLSEWEHDKQQLLTETSDLKTKMATL-------ERELKQQRESTQAVEAKAQQLQEEGERRAAAERQVQQLEEQVQQLEAQVQLLVGRLEGAGQQVCWASTELDKEKARVDSMVRHQESLQAKQRALLKQLDSLDQEREELRGSLDEAEAQRARVEEQ---LQSEREQGQCQLRAQQELLQSLQREKQGLEQATTDLRLTILELERELEELKERERLLVAFPDLHRPTE 553

HSP 2 Score: 29.261 bits (64), Expect = 4.355e-32
Identity = 14/39 (35.90%), Postives = 23/39 (58.97%), Query Frame = 3 
Query: 1812 SGNIEQDLINQIKSNAARISLLSEQNRDLEQALEKLNQT 1928
            SGN+   +  Q++SN  RI +L E+N  L+  L K+ + 
Sbjct:  574 SGNVTDHMERQVQSNDIRIRVLQEENGRLQSMLSKIREV 612
[Close]
BLAST of coiled-coil domain-containing protein 157 isoform X2 vs. TrEMBL
Match: A0A1S3JCA9 (coiled-coil domain-containing protein 157 isoform X2 OS=Lingula unguis OX=7574 GN=LOC106172015 PE=4 SV=1)

HSP 1 Score: 212.616 bits (540), Expect = 5.560e-55
Identity = 152/581 (26.16%), Postives = 298/581 (51.29%), Query Frame = 1 
Query:   34 MSFLLGSEYCIQSLSNDVSDVQSCIKDIIFKVGRINSISWKFPDKFACDLNIDEYLTNYKYNPNDSESNQISHIILLELIIDRVCLLLQLHCETIEKIVSKDKLSNTNCKSDSKTKMMSPCLGLTSKKHWNKLCQLSIYIDNIQQEIGQXXXXXXXXXXXXXXXXXXXMNENAAEEVGTNDNISKQAGDWLRTLENENKVNINKRKPVVGSISKDMTFKSSQTVDTAFKPCESCHISQTCLRESSSILMKVLKQESQPSSLMKLQHEILNLDWLSDKKIMQIKDCFAKDLDKVCAIYQNIKQKEIKTVTELSDCRNMCKNFTEALEKEKCEMLASETKFSRQIHEFGVENEKLTNTISQLKLQTASLMEEIELKDKQINQDRAQLKQHILEK-------QNINEELDKLKVSI-SNFNVNATDPFE------ALAIIKRKISDLTDNISQLNSTIQNQKSINENLTLTENVIKNKEEKLVKRLQSLTEQKHKLEEKIDILQDQVESNQESIRALENERNSMSMKLSNQTILIETITKAKDEFRVRITELQSQLEGMQQTILEINQGKDLLVNYPDLNGPLD 1734
            M+ LLGS++CI+SL +DV+D+Q+ + D+  + G  NS SWKFPDK   +++I++ L  Y Y+  D E  Q+SHI LLEL+IDR+ LL+Q   +  ++      L++++  + +  +  S  +GLT +K+WNK+  L   +  +Q EI    +  + L    E+   +  N +   +     N    A   L    N++        P    ISKD + KSSQT++TAF PCE+C   Q CL+E    ++ V + +  PS+L K + +I  LDW++   + +      KDL K+     +++       ++L+  +  CK       + K +    E    RQ      + ++    I  ++ Q    + E++ ++ ++  D+ +L+ ++++        Q   E+L+  KV +  +   NA++  E       ++ +K +++D+ +        +  Q+ +N+ L+  +  ++ K+E L++R+ +L +    L+++++ ++D+ +S QE++  +  E+  +  ++S Q I +  + K K      + +L+  +  + Q + E  + + LLV YPDLNGP++
Sbjct:    1 MAHLLGSKFCIESLRSDVTDLQAAVSDVFSRTGPTNSTSWKFPDKIGSEIDIEDLLETYDYS-EDEEERQVSHISLLELVIDRLVLLIQGMSKYADQT-----LASSSRSTPANLQGSSVSIGLTVRKYWNKMVHLHANVQQLQSEIKSKNRKIQTLEDAAEHACNSPSNPHIHLKPSEGLNPKSPAQSGLIPPSNQDSF------PACKDISKDCSNKSSQTIETAFVPCEACEKVQHCLKEIGENVVNVCQTQGLPSALAKYKKQISGLDWMTANDVTRWSSEQNKDLVKINKHLSHLESTIEPLKSDLAVSQESCKKL-----QAKVDDFDKEMSLERQTQ--TAQRKQYEQKIKDIEQQNNEAVCEVQRQNDKLRSDKKELETNVVKAREELASTQKRIEDLEATKVQLLKDLQENASNSSEIQTLEGVVSDLKSQLNDVKEKFDTTTKELAKQQVVNKTLSRNKEALQGKQESLLQRIDALDQDNESLKQRVEEIEDERDSLQENLDKVTEEKEKLVEEMSVQQIHLTELNKEKSSLEQAMQQLEQNIAALTQDLQEAQERERLLVEYPDLNGPVN 562
[Close]
BLAST of coiled-coil domain-containing protein 157 isoform X2 vs. TrEMBL
Match: A0A1S3JDS8 (coiled-coil domain-containing protein 157 isoform X1 OS=Lingula unguis OX=7574 GN=LOC106172015 PE=4 SV=1)

HSP 1 Score: 212.231 bits (539), Expect = 1.452e-54
Identity = 152/581 (26.16%), Postives = 298/581 (51.29%), Query Frame = 1 
Query:   34 MSFLLGSEYCIQSLSNDVSDVQSCIKDIIFKVGRINSISWKFPDKFACDLNIDEYLTNYKYNPNDSESNQISHIILLELIIDRVCLLLQLHCETIEKIVSKDKLSNTNCKSDSKTKMMSPCLGLTSKKHWNKLCQLSIYIDNIQQEIGQXXXXXXXXXXXXXXXXXXXMNENAAEEVGTNDNISKQAGDWLRTLENENKVNINKRKPVVGSISKDMTFKSSQTVDTAFKPCESCHISQTCLRESSSILMKVLKQESQPSSLMKLQHEILNLDWLSDKKIMQIKDCFAKDLDKVCAIYQNIKQKEIKTVTELSDCRNMCKNFTEALEKEKCEMLASETKFSRQIHEFGVENEKLTNTISQLKLQTASLMEEIELKDKQINQDRAQLKQHILEK-------QNINEELDKLKVSI-SNFNVNATDPFE------ALAIIKRKISDLTDNISQLNSTIQNQKSINENLTLTENVIKNKEEKLVKRLQSLTEQKHKLEEKIDILQDQVESNQESIRALENERNSMSMKLSNQTILIETITKAKDEFRVRITELQSQLEGMQQTILEINQGKDLLVNYPDLNGPLD 1734
            M+ LLGS++CI+SL +DV+D+Q+ + D+  + G  NS SWKFPDK   +++I++ L  Y Y+  D E  Q+SHI LLEL+IDR+ LL+Q   +  ++      L++++  + +  +  S  +GLT +K+WNK+  L   +  +Q EI    +  + L    E+   +  N +   +     N    A   L    N++        P    ISKD + KSSQT++TAF PCE+C   Q CL+E    ++ V + +  PS+L K + +I  LDW++   + +      KDL K+     +++       ++L+  +  CK       + K +    E    RQ      + ++    I  ++ Q    + E++ ++ ++  D+ +L+ ++++        Q   E+L+  KV +  +   NA++  E       ++ +K +++D+ +        +  Q+ +N+ L+  +  ++ K+E L++R+ +L +    L+++++ ++D+ +S QE++  +  E+  +  ++S Q I +  + K K      + +L+  +  + Q + E  + + LLV YPDLNGP++
Sbjct:    1 MAHLLGSKFCIESLRSDVTDLQAAVSDVFSRTGPTNSTSWKFPDKIGSEIDIEDLLETYDYS-EDEEERQVSHISLLELVIDRLVLLIQGMSKYADQT-----LASSSRSTPANLQGSSVSIGLTVRKYWNKMVHLHANVQQLQSEIKSKNRKIQTLEDAAEHACNSPSNPHIHLKPSEGLNPKSPAQSGLIPPSNQDSF------PACKDISKDCSNKSSQTIETAFVPCEACEKVQHCLKEIGENVVNVCQTQGLPSALAKYKKQISGLDWMTANDVTRWSSEQNKDLVKINKHLSHLESTIEPLKSDLAVSQESCKKL-----QAKVDDFDKEMSLERQTQT--AQRKQYEQKIKDIEQQNNEAVCEVQRQNDKLRSDKKELETNVVKAREELASTQKRIEDLEATKVQLLKDLQENASNSSEIQTLEGVVSDLKSQLNDVKEKFDTTTKELAKQQVVNKTLSRNKEALQGKQESLLQRIDALDQDNESLKQRVEEIEDERDSLQENLDKVTEEKEKLVEEMSVQQIHLTELNKEKSSLEQAMQQLEQNIAALTQDLQEAQERERLLVEYPDLNGPVN 562
[Close]
BLAST of coiled-coil domain-containing protein 157 isoform X2 vs. TrEMBL
Match: A0A267GZ09 (C2H2-type domain-containing protein (Fragment) OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig010910g1 PE=4 SV=1)

HSP 1 Score: 208.379 bits (529), Expect = 3.380e-53
Identity = 165/598 (27.59%), Postives = 289/598 (48.33%), Query Frame = 1 
Query:   31 IMSFLLGSEYCIQSLSNDVSDVQSCIKDIIFKVGRINSISWKFPDKFACDLNIDEYLTNYKYNPNDSESNQISHIILLELIIDRVCLLLQLHCETIEKIVSKDKLSNTNCKSDSKTKMMSPCLGLTSKKHWNKLCQLSIYIDNIQQEIGQXXXXXXXXXXXXXXXXXXXMNENAAEEVGTNDNISKQAGDWLRTLENENKVNINKRKPVVGSISKDMTFKSSQTVDTAFKPCESCHISQTCLRESSSILMKVLKQESQPSSLMKLQHEI------LNLDWLSDKKIMQIKDCFAKDLDKVCAIYQNIKQKEIKTVTELSDCRNMCK----NFTEALEKEKC-------EMLASETKFSRQIHEFGVENEKLTNTISQLKLQTASLMEEIELKDKQINQDRAQLKQHILEKQNINEELDKLKVSISNF----NVNATDPFEALAIIKRKISDLTDNISQLNSTIQNQKSINENLTLTENVIKNKEEKLVKRLQSLTEQKHKLEEKIDILQDQVESNQESIRALENERNSMSMKLSNQTILIETITKAKDEFRVRITELQSQLEGMQQTILEINQGKDLLVNYPDLNGPLDKFVIVNVEG 1761
            IM+ LLGSEYC++SLS+D  D+ + ++++I K G +  +SWKFPDK ACDL+I   L  Y +  ++ E+NQ+SHI+LLEL+IDR  LLLQ+    + + +     +     S S+T      LGL +KK WN++ Q+S+ +  +  E                   +    +   EEV                 +N  K N   + P+  ++    + KS QTV+TAF PC+SC   Q      S+ L  + ++E  PSSL   + ++       + DWL+           A DL +     +    + +K   ++SD     K    + T ALE+ K        E  A   K ++   E   + +KL         Q +S  + +E    Q+ +D    K+ I +++ + + LD++K  +       +++  D   A+  +  +++DLTD + Q     Q   +  ENL      ++ K     +R+  L+ +  +L+E +D L++  ++++ S + LE E  +  M+     +LI+T+T+A+D   + +  L+SQ+  +Q ++ +    K LL+ YPDLNGP+++    +VEG
Sbjct:    1 IMAHLLGSEYCLKSLSSDARDLHNVLQELIAKAGPVPVMSWKFPDKKACDLDIPYLLQQYAFCMDEPEANQVSHIVLLELVIDRYNLLLQV----LSQFILTHLPAEAGQSSGSQTHAGGSSLGLAAKKFWNRMGQMSLLVRQLTDEA----------------RLSELRQQQQKEEVS----------------QNVVKSNKTDQSPIRSAVPN--STKSCQTVETAFVPCDSCSEVQHGFSRISAHLSALCEKERLPSSLRIYRAQLQQANGGFDGDWLA-----------ASDLVRWSVELEKEANRLVKHFNQVSDTSAQLKRQNADLTAALEQAKTREVKFDQERAADAEKAAKSRRELESKMDKLVKQYEATVDQVSSANKALEASKLQLMKDIEAAKKSIEQQEELIKLLDRVKNRVKQVSKRDDLSLEDLELAVGSVGERLTDLTDQLCQAREETQAAATQCENLARQNESLQAKHRMTAERVAELSAENEQLKEALDELEEFKDNHRSSGKDLEKELVAAKMQNKESEMLIKTLTEAQDNLTLSVQRLKSQVSDLQTSLQKSEDEKRLLIEYPDLNGPVNQ----DVEG 545
[Close]
BLAST of coiled-coil domain-containing protein 157 isoform X2 vs. TrEMBL
Match: A0A267GJS4 (C2H2-type domain-containing protein (Fragment) OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig010910g2 PE=4 SV=1)

HSP 1 Score: 207.994 bits (528), Expect = 4.922e-53
Identity = 165/598 (27.59%), Postives = 289/598 (48.33%), Query Frame = 1 
Query:   31 IMSFLLGSEYCIQSLSNDVSDVQSCIKDIIFKVGRINSISWKFPDKFACDLNIDEYLTNYKYNPNDSESNQISHIILLELIIDRVCLLLQLHCETIEKIVSKDKLSNTNCKSDSKTKMMSPCLGLTSKKHWNKLCQLSIYIDNIQQEIGQXXXXXXXXXXXXXXXXXXXMNENAAEEVGTNDNISKQAGDWLRTLENENKVNINKRKPVVGSISKDMTFKSSQTVDTAFKPCESCHISQTCLRESSSILMKVLKQESQPSSLMKLQHEI------LNLDWLSDKKIMQIKDCFAKDLDKVCAIYQNIKQKEIKTVTELSDCRNMCK----NFTEALEKEKC-------EMLASETKFSRQIHEFGVENEKLTNTISQLKLQTASLMEEIELKDKQINQDRAQLKQHILEKQNINEELDKLKVSISNF----NVNATDPFEALAIIKRKISDLTDNISQLNSTIQNQKSINENLTLTENVIKNKEEKLVKRLQSLTEQKHKLEEKIDILQDQVESNQESIRALENERNSMSMKLSNQTILIETITKAKDEFRVRITELQSQLEGMQQTILEINQGKDLLVNYPDLNGPLDKFVIVNVEG 1761
            IM+ LLGSEYC++SLS+D  D+ + ++++I K G +  +SWKFPDK ACDL+I   L  Y +  ++ E+NQ+SHI+LLEL+IDR  LLLQ+    + + +     +     S S+T      LGL +KK WN++ Q+S+ +  +  E                   +    +   EEV                 +N  K N   + P+  ++    + KS QTV+TAF PC+SC   Q      S+ L  + ++E  PSSL   + ++       + DWL+           A DL +     +    + +K   ++SD     K    + T ALE+ K        E  A   K ++   E   + +KL         Q +S  + +E    Q+ +D    K+ I +++ + + LD++K  +       +++  D   A+  +  +++DLTD + Q     Q   +  ENL      ++ K     +R+  L+ +  +L+E +D L++  ++++ S + LE E  +  M+     +LI+T+T+A+D   + +  L+SQ+  +Q ++ +    K LL+ YPDLNGP+++    +VEG
Sbjct:    1 IMAHLLGSEYCLKSLSSDARDLHNVLQELIAKAGPVPVMSWKFPDKKACDLDIPYLLQQYAFCMDEPEANQVSHIVLLELVIDRYNLLLQV----LSQFILTHLPAEAGQSSGSQTHAGGSSLGLAAKKFWNRMGQMSLLVRQLTDEA----------------RLSELRQQQQKEEVS----------------QNVVKSNKTDQSPIRSAVPN--STKSCQTVETAFVPCDSCSEVQHGFSRISAHLSALCEKERLPSSLRIYRAQLQQANGGFDGDWLA-----------ASDLVRWSVELEKEANRLVKHFNQVSDTSAQLKRQNADLTAALEQAKTREVKFDQERAADAEKAAKSRRELESKMDKLVKQYEATVDQVSSANKALEASKLQLMKDIEAAKKSIEQQEELIKLLDRVKNRVKQVSKRDDLSLEDLELAVGSVGERLTDLTDQLCQAREETQAAATQCENLARQNESLQAKHRMTAERVAELSAENEQLKEALDELEEFKDNHRSSGKDLEKELVAAKMQNKESEMLIKTLTEAQDNLTLSVQRLKSQVSDLQTSLQKSEDEKRLLIEYPDLNGPVNQ----DVEG 545
[Close]
BLAST of coiled-coil domain-containing protein 157 isoform X2 vs. TrEMBL
Match: A0A2T7PE22 (Uncharacterized protein OS=Pomacea canaliculata OX=400727 GN=C0Q70_07084 PE=4 SV=1)

HSP 1 Score: 172.94 bits (437), Expect = 4.666e-42
Identity = 150/592 (25.34%), Postives = 287/592 (48.48%), Query Frame = 1 
Query:   34 MSFLLGSEYCIQSLSNDVSDVQSCIKDIIFKVGRINSISWKFPDKFACDLNIDEYLTNYKYNPNDSESNQISHIILLELIIDRVCLLLQLHCETIEKIVSKDKLSNTNCKSDSKTKMMSPCLGLTSKKHWNKLCQLSIYIDNIQQEIGQXXXXXXXXXXXXXXXXXXXMNENAAEEVGTNDNISKQAGDWLRTLENENKVNINKRKPVVGSISKDMTFKSSQTVDTAFKPCESCHISQTCLRESSSILMKVLKQESQPSSLMKLQHEILNLDWLSDKKIMQIKDCFAKDLDKVCAIYQNIKQKEIKTVTE-LSDCRNMCKNFTEALEKEKCEMLASETKFSRQIHEFGVENEKLTNTISQLKLQTASLMEEIELKDKQINQDRAQLKQHILEKQNINEELDKLKVSISNFNV-----------------NATDPFEALAIIKRKISDLTDNISQLNS-------TIQNQKSINENLTLTENVIKNKEEKLVKRLQSLTEQKHKLEEKIDILQDQVESNQESIRALENERNSMSMKLSNQTILIETITKAKDEFRVRITELQSQLEGMQQTILEINQGKDLLVNYPDLNGPLD 1734
            M+ LLG+  C+++L +D+ DVQ  I D+  + G I   SWKFPDK + +L+ +E L  Y Y P+++E NQ++HI L EL+IDR+   +Q     + +I   DK S+      +        +GL  +  W++L        N Q  I Q    NK+    +  L+    N ++      + ++S ++      L+ E++     +   V +IS D   KS QTV+TAF PCESC + Q  +RES  ++++V +++  PS L K + ++ ++ WLS   + +      KD+ ++C        K I+ V+  +   +     F +  E +K E +A E + +  + +   E ++      ++KL+   +  E  L D +      Q K+ +L+  N+ + L+  K+  S   +                 N T+  E L  ++ ++  L   +S++ S       T+  ++  N++       +K K+  L +R+  L E+   L E++  L+++ +  +ES++    E   M  + +NQ ++I+ +   K E    I E ++Q++ ++  + +  + + +L+ YPDLNGP++
Sbjct:    1 MADLLGNRLCMENLQSDIQDVQWIINDVSSRTGPIKLSSWKFPDKLSWELDTEELLQTYGYAPDETEENQVAHIALYELLIDRLVSFIQGTAIYLNQIQHLDKASDNASAPPTS-------VGLAVRHFWDQLV-------NAQTVILQLYSQNKSNATKISELEKTIKNLSS-----QHAHLSSKSSFATHFLDQESQYY---KSSDVKTISHDEISKSCQTVETAFVPCESCDLVQKKMRESGDLIIQVCQKQGLPSCLRKYRSQLADVKWLSSNDVSRWMAEENKDVQRLC--------KHIECVSNVIEPLKAEVTAFQQ--ETQKAEKVAKECERALNLEK---ETQEAIKKQYEIKLKKTQIEHEFILADLE-----CQKKELLLKHTNLEKVLEDHKIKSSELQISLEQTEAKCLELKRDLQNKTEAVERLESVENEVESLRQELSEVTSKLEVATKTLTKEQGKNKSAAQHNQQVKTKQNMLSERISELNEENENLREQVGALEEESQHLEESLQEARREAQQMQKEKANQEVIIKNLNAEKAELERCIEETEAQIKELEVQVEQAKERERMLIEYPDLNGPVN 552

HSP 2 Score: 30.0314 bits (66), Expect = 4.666e-42
Identity = 13/36 (36.11%), Postives = 24/36 (66.67%), Query Frame = 3 
Query: 1812 SGNIEQDLINQIKSNAARISLLSEQNRDLEQALEKL 1919
            +G+I  D+ NQ+K+N  RI +L + N  L +++ K+
Sbjct:  558 TGDIATDMENQVKANIMRIQVLEDLNERLRRSITKV 593
[Close]
BLAST of coiled-coil domain-containing protein 157 isoform X2 vs. Ensembl Cavefish
Match: ENSAMXT00000035197.1 (pep primary_assembly:Astyanax_mexicanus-2.0:6:30138919:30139170:1 gene:ENSAMXG00000038773.1 transcript:ENSAMXT00000035197.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 84.3445 bits (207), Expect = 1.532e-19
Identity = 37/83 (44.58%), Postives = 56/83 (67.47%), Query Frame = 1 
Query:   34 MSFLLGSEYCIQSLSNDVSDVQSCIKDIIFKVGRINSISWKFPDKFACDLNIDEYLTNYKYNPNDSESNQISHIILLELIIDR 282
            M+ LLG + C++SL  DV D+Q+ + D+  + G +   SWKFPDK +C++++ + L  Y Y   + E NQ SHI+LLEL+IDR
Sbjct:    1 MTHLLGRQDCVESLRRDVIDLQAAVLDVFSRTGPVRVPSWKFPDKVSCNVDLVQLLQEYDYTEGEPEFNQHSHIVLLELVIDR 83
[Close]
BLAST of coiled-coil domain-containing protein 157 isoform X2 vs. Ensembl Nematostella
Match: EDO31484 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SXT8])

HSP 1 Score: 125.176 bits (313), Expect = 3.419e-30
Identity = 90/285 (31.58%), Postives = 145/285 (50.88%), Query Frame = 1 
Query:   34 MSFLLGSEYCIQSLSNDVSDVQSCIKDIIFKVGRINSISWKFPDKFACDLNIDEYLTNYKYNPNDSESNQISHIILLELIIDRVCLLLQLHCETIEKIVSKDKLSNTNCKSDSKTKMMSP-CLGLTSKKHWNKLCQLSIYIDNIQ--QEIGQXXXXXXXXXXXXXXXXXXXMNENAAEEVGTNDNIS------KQAGDWLRTLENENKVNINKRKPVVGSISKDMTF-------------KSSQTVDTAFKPCESCHISQTCLRESSSILMKVLKQESQPSSLMK 822
            M+ LLG+E C+ SLS DVSD+Q+ I D+I +VG +   SWK+PDK + +L+I + L  Y Y+  D +  ++SHIIL EL+IDR+ LLLQ     I++ +   K S    +  S   + S   +GL +KK+WNK  ++   +  IQ   E            +     +     +   ++ G + ++S       Q+    R + +  + ++N R P   S S DMT               ++QT DTAF PCE+C  +Q  L +  +++M + + +  PSSL K
Sbjct:    1 MAHLLGTESCLDSLSRDVSDIQAVITDVISRVGPVRFPSWKYPDKVSSELDIQDLLERYCYS-EDEDHCKMSHIILFELVIDRLVLLLQSMSHFIDQTL---KTSGKESRPLSGVLVGSAMSVGLVAKKYWNKAVKMQQSMQQIQLEDETKNKTLFKMEDTIGDLRDEIKMFKQVLDKKRGKHTSVSGKIKSHGQSASSARFILSPTE-SLNLRSP---SPSHDMTLLVEDVAFAKTLQESATQTYDTAFIPCEACSRTQQNLLDVGNMVMNLCESQGLPSSLAK 277
[Close]
BLAST of coiled-coil domain-containing protein 157 isoform X2 vs. Ensembl Medaka
Match: ccdc157 (coiled-coil domain containing 157 [Source:NCBI gene;Acc:101162608])

HSP 1 Score: 101.293 bits (251), Expect = 7.615e-22
Identity = 128/570 (22.46%), Postives = 263/570 (46.14%), Query Frame = 1 
Query:   34 MSFLLGSEYCIQSLSNDVSDVQSCIKDIIFKVGRINSISWKFPDKFACDLNIDEYLTNYKYNPNDSESNQISHIILLELIIDRVCLLLQLHCETIEKIVSKDKLSNTNCKSDSKTKMMSPCLGLTSKKHWNKLCQLSIYIDNIQQEIGQXXXXXXXXXXXXXXXXXXXMNENAAEEVGTNDNISKQAGDWLRTLENENKVNINKRKPVVGSISKDMTFKSSQTVDTAFKPCESCHISQTCLRESSSILMKVLKQESQPSSLMKLQH---EILNLDWLSDKKIMQIKDCFAKDLDKVCAIYQNIKQKEIKTVTELSDCRNMCKNFTEALEKEKCEMLASETKFSRQIHEFGVENEKLTNTISQLKLQTASLMEEIELKDKQINQDRAQLKQHILEKQNINEELDKLKVSISNFNVNATDP---FEALAIIKRKISDLTDNISQLNSTIQNQKSINENLTLTENVIKNKEEKLVKRLQSLTEQKHKLEEK-IDILQDQVESNQESIRALENERNSMSMKLSNQTILIETITKAKDEFRVRITELQSQLEGMQQTILEINQGKDLLVNYPDLN 1722
            MS LLG +  I++L  D+ D+Q  + D++ + G + + SWKFPDK +C L+I   L  Y +   + + NQ SHIILLEL+IDR+  LLQ        + ++ ++     +  +    MS  +GL  + +W  L Q +    N++  + ++  +    +    +  ++        +    +NI         T+ +  + + + +     + S +++ +++Q   T+  PC +CH  Q+ LR++   L+ + + E  PSSL  L     E + +  L+   + Q  +   +D+ ++    Q+++     TV  L D     +   EA+   + ++   +  F +Q+       EK    I QL+      ++E +   KQ  Q   Q ++H   K+ IN         I+  N N       F A    +++I  L + +S +   +  ++S            + K++ L+KR++ L E+  +L+++ +D  + Q++ + E ++ + +E+  + ++ + Q  L   + K K    +R  EL+ QL  +   +  +   + +LV +P+L+
Sbjct:    1 MSLLLGRQDSIKNLRKDLIDIQGAVLDVLSRTGPVCASSWKFPDKLSCHLDIVALLEEYDFVAGEDDFNQHSHIILLELMIDRLLFLLQ-----SVSVYAEQQMGVHRPEGAAHRGSMS--VGLVVRNYWGDLLQFADKKSNVESPLNRSSTSCSRHSSISWSSTSSF-------KFLPQNNI---------TISSPEQTSFHPK-----TASHNVSCQTAQ---TSLIPCGTCHQVQSLLRKTGESLIDLFQSEGLPSSLQPLSAVVDETVRVGHLTPGDVAQWANEQLRDMRRLAKHLQDVR----GTVLPLQDRVAAAETDREAI---RSQLKTVQKDFEQQL-------EKQQTNIEQLEFS----LQEAQRSAKQTEQ--KQQEEHKQLKKGINH--------INQHNKNKLGSCLNFFACCQQQQRIHQLEEQLSDIQLLLDKERS-----------TQVKQKSLLKRVEDLDEECEELKKQLVDSEEAQMKLDNE-LQQMSDEKKQLQVQTAQQQDLCGELQKKKQRLEMREEELKQQLHELMDRVRALRDRERILVAFPELH 499
[Close]
BLAST of coiled-coil domain-containing protein 157 isoform X2 vs. Ensembl Medaka
Match: ccdc157 (coiled-coil domain containing 157 [Source:NCBI gene;Acc:101162608])

HSP 1 Score: 92.4337 bits (228), Expect = 5.089e-19
Identity = 47/137 (34.31%), Postives = 76/137 (55.47%), Query Frame = 1 
Query:   34 MSFLLGSEYCIQSLSNDVSDVQSCIKDIIFKVGRINSISWKFPDKFACDLNIDEYLTNYKYNPNDSESNQISHIILLELIIDRVCLLLQLHCETIEKIVSKDKLSNTNCKSDSKTKMMSPCLGLTSKKHWNKLCQLS 444
            MS LLG +  I++L  D+ D+Q  + D++ + G + + SWKFPDK +C L+I   L  Y +   + + NQ SHIILLEL+IDR+  LLQ        + ++ ++     +  +    MS  +GL  + +W  L Q +
Sbjct:   40 MSLLLGRQDSIKNLRKDLIDIQGAVLDVLSRTGPVCASSWKFPDKLSCHLDIVALLEEYDFVAGEDDFNQHSHIILLELMIDRLLFLLQ-----SVSVYAEQQMGVHRPEGAAHRGSMS--VGLVVRNYWGDLLQFA 169
[Close]
BLAST of coiled-coil domain-containing protein 157 isoform X2 vs. Planmine SMEST
Match: SMESG000042794.1 (SMESG000042794.1)

HSP 1 Score: 1104.35 bits (2855), Expect = 0.000e+0
Identity = 571/575 (99.30%), Postives = 572/575 (99.48%), Query Frame = 1 
Query:   34 MSFLLGSEYCIQSLSNDVSDVQSCIKDIIFKVGRINSISWKFPDKFACDLNIDEYLTNYKYNPNDSESNQISHIILLELIIDRVCLLLQLHCETIEKIVSKDKLSNTNCKSDSKTKMMSPCLGLTSKKHWNKLCQLSIYIDNIQQEIGQXXXXXXXXXXXXXXXXXXXMNENAAEEVGTNDNISKQAGDWLRTLENENKVNINKRKPVVGSISKDMTFKSSQTVDTAFKPCESCHISQTCLRESSSILMKVLKQESQPSSLMKLQHEILNLDWLSDKKIMQIKDCFAKDLDKVCAIYQNIKQKEIKTVTELSDCRNMCKNFTEALEKEKCEMLASETKFSRQIHEFGVENEKLTNTISQLKLQTASLMEEIELKDKQINQDRAQLKQHILEKQNINEELDKLKVSISNFNVNATDPFEALAIIKRKISDLTDNISQLNSTIQNQKSINENLTLTENVIKNKEEKLVKRLQSLTEQKHKLEEKIDILQDQVESNQESIRALENERNSMSMKLSNQTILIETITKAKDEFRVRITELQSQLEGMQQTILEINQGKDLLVNYPDLNGPLDKFVIVNVE 1758
            MSFLLGSEYCIQSLSNDVSDVQSCIKDIIFKVGRINSISWKFPDKFACDLNIDEYLTNYKYNPNDSESNQISHIILLELIIDRVCLLLQLHCETIEKIVSKDKLSNTNCKSDSKTKMMSPCLGLTSKKHWNKLCQLSIYIDNIQQEIGQAKKTNKNLNLTLENLKANKMNENAAEEVGTNDNISKQAGDWLRTLENENKVNINKRKPVVGSISKDMTFKSSQTVDTAFKPCESCHISQTCLRESSSILMKVLKQESQPSSLMKLQHEILNLDWLSDKKIMQIKDCFAKDLDKVCAIYQNIKQKEIKTVTELSDCRNMCKNFTEALEKEKCEMLASETKFSRQIHEFGVENEKLTNTISQLKLQTASLMEEIELKDKQINQDRAQLKQHILEKQNINEELDKLKVSISNFNVNATDPFEALAIIKRKISDLTDNISQLNSTIQNQKSINENLTLTENVIKNKEEKLVKRLQSLTEQKHKLEEKIDILQDQVESNQESIRALENERNSMSMKLSNQTILIETITKAKDEFRVRITELQSQLEGMQQTILEINQGKDLLVNYPDLNGPLDKF   N+E
Sbjct:    1 MSFLLGSEYCIQSLSNDVSDVQSCIKDIIFKVGRINSISWKFPDKFACDLNIDEYLTNYKYNPNDSESNQISHIILLELIIDRVCLLLQLHCETIEKIVSKDKLSNTNCKSDSKTKMMSPCLGLTSKKHWNKLCQLSIYIDNIQQEIGQAKKTNKNLNLTLENLKANKMNENAAEEVGTNDNISKQAGDWLRTLENENKVNINKRKPVVGSISKDMTFKSSQTVDTAFKPCESCHISQTCLRESSSILMKVLKQESQPSSLMKLQHEILNLDWLSDKKIMQIKDCFAKDLDKVCAIYQNIKQKEIKTVTELSDCRNMCKNFTEALEKEKCEMLASETKFSRQIHEFGVENEKLTNTISQLKLQTASLMEEIELKDKQINQDRAQLKQHILEKQNINEELDKLKVSISNFNVNATDPFEALAIIKRKISDLTDNISQLNSTIQNQKSINENLTLTENVIKNKEEKLVKRLQSLTEQKHKLEEKIDILQDQVESNQESIRALENERNSMSMKLSNQTILIETITKAKDEFRVRITELQSQLEGMQQTILEINQGKDLLVNYPDLNGPLDKFESGNIE 575

HSP 2 Score: 309.301 bits (791), Expect = 5.016e-94
Identity = 160/161 (99.38%), Postives = 161/161 (100.00%), Query Frame = 3 
Query: 1809 KSGNIEQDLINQIKSNAARISLLSEQNRDLEQALEKLNQTYXXXXXXXXXXXVKATNNLSNTSGLPPNVASLELSRPHSKMSHVGQSMPKRQTHRQSTSSRPPSRDNIASQGSIIQWSVSNQKPSHANVIFVCETCGRSYQQKSDLDVHKEYCAGRRRRSE 2291
            +SGNIEQDLINQIKSNAARISLLSEQNRDLEQALEKLNQTYSSNKSIISNSNVKATNNLSNTSGLPPNVASLELSRPHSKMSHVGQSMPKRQTHRQSTSSRPPSRDNIASQGSIIQWSVSNQKPSHANVIFVCETCGRSYQQKSDLDVHKEYCAGRRRRSE
Sbjct:  570 ESGNIEQDLINQIKSNAARISLLSEQNRDLEQALEKLNQTYSSNKSIISNSNVKATNNLSNTSGLPPNVASLELSRPHSKMSHVGQSMPKRQTHRQSTSSRPPSRDNIASQGSIIQWSVSNQKPSHANVIFVCETCGRSYQQKSDLDVHKEYCAGRRRRSE 730
The following BLAST results are available for this feature:
BLAST of coiled-coil domain-containing protein 157 isoform X2 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
CCDC1579.889e-3323.15coiled-coil domain containing 157 [Source:HGNC Sym... [more]
CCDC1579.889e-3323.15coiled-coil domain containing 157 [Source:HGNC Sym... [more]
CCDC1571.421e-2538.13coiled-coil domain containing 157 [Source:HGNC Sym... [more]
CCDC1571.619e-2538.13coiled-coil domain containing 157 [Source:HGNC Sym... [more]
CCDC1571.163e-2146.99coiled-coil domain containing 157 [Source:HGNC Sym... [more]
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BLAST of coiled-coil domain-containing protein 157 isoform X2 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of coiled-coil domain-containing protein 157 isoform X2 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of coiled-coil domain-containing protein 157 isoform X2 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 2
Match NameE-valueIdentityDescription
ccdc1573.948e-2124.10coiled-coil domain containing 157 [Source:ZFIN;Acc... [more]
ccdc1572.255e-1626.97coiled-coil domain containing 157 [Source:ZFIN;Acc... [more]
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BLAST of coiled-coil domain-containing protein 157 isoform X2 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 2
Match NameE-valueIdentityDescription
tlx11.605e-2146.99T cell leukemia homeobox 1 [Source:Xenbase;Acc:XB-... [more]
ENSXETT00000018529.19.709e-1223.86coiled-coil domain containing 157 [Source:NCBI gen... [more]
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BLAST of coiled-coil domain-containing protein 157 isoform X2 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 2
Match NameE-valueIdentityDescription
Ccdc1571.353e-3323.83coiled-coil domain containing 157 [Source:MGI Symb... [more]
Ccdc1579.180e-921.16coiled-coil domain containing 157 [Source:MGI Symb... [more]
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BLAST of coiled-coil domain-containing protein 157 isoform X2 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 3
Match NameE-valueIdentityDescription
sp|A4IFI1|CC157_BOVIN3.775e-3625.13Coiled-coil domain-containing protein 157 OS=Bos t... [more]
sp|Q5SPX1|CC157_MOUSE8.228e-3323.83Coiled-coil domain-containing protein 157 OS=Mus m... [more]
sp|Q569K6|CC157_HUMAN4.355e-3223.15Coiled-coil domain-containing protein 157 OS=Homo ... [more]
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BLAST of coiled-coil domain-containing protein 157 isoform X2 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A1S3JCA95.560e-5526.16coiled-coil domain-containing protein 157 isoform ... [more]
A0A1S3JDS81.452e-5426.16coiled-coil domain-containing protein 157 isoform ... [more]
A0A267GZ093.380e-5327.59C2H2-type domain-containing protein (Fragment) OS=... [more]
A0A267GJS44.922e-5327.59C2H2-type domain-containing protein (Fragment) OS=... [more]
A0A2T7PE224.666e-4225.34Uncharacterized protein OS=Pomacea canaliculata OX... [more]
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BLAST of coiled-coil domain-containing protein 157 isoform X2 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 1
Match NameE-valueIdentityDescription
ENSAMXT00000035197.11.532e-1944.58pep primary_assembly:Astyanax_mexicanus-2.0:6:3013... [more]
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BLAST of coiled-coil domain-containing protein 157 isoform X2 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of coiled-coil domain-containing protein 157 isoform X2 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of coiled-coil domain-containing protein 157 isoform X2 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1
Match NameE-valueIdentityDescription
EDO314843.419e-3031.58Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of coiled-coil domain-containing protein 157 isoform X2 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 2
Match NameE-valueIdentityDescription
ccdc1577.615e-2222.46coiled-coil domain containing 157 [Source:NCBI gen... [more]
ccdc1575.089e-1934.31coiled-coil domain containing 157 [Source:NCBI gen... [more]
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BLAST of coiled-coil domain-containing protein 157 isoform X2 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 1
Match NameE-valueIdentityDescription
SMESG000042794.15.016e-9499.30SMESG000042794.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30009257 ID=SMED30009257|Name=coiled-coil domain-containing protein 157 isoform X2|organism=Schmidtea mediterranea sexual|type=transcript|length=2292bp
GTTCAATATTTTAAACGGTTTCTATAGTAAATAATGTCTTTTTTATTGGG
AAGCGAGTATTGTATTCAAAGTTTATCAAATGATGTAAGTGATGTCCAGT
CATGCATAAAAGATATAATTTTTAAAGTTGGTCGAATTAATTCTATTTCA
TGGAAATTTCCAGATAAATTTGCATGTGATTTGAATATAGATGAATATTT
AACAAATTATAAATATAATCCCAATGACAGCGAGAGCAATCAAATTTCTC
ACATAATACTTTTGGAACTAATAATCGATCGAGTTTGTTTGCTTCTTCAA
TTACATTGTGAAACAATTGAAAAAATTGTATCAAAAGATAAATTATCTAA
TACGAATTGCAAAAGTGATTCGAAGACAAAAATGATGTCGCCATGTTTAG
GACTGACATCGAAGAAACATTGGAATAAATTATGTCAACTTTCTATCTAC
ATTGACAATATCCAACAAGAAATTGGACAAGCTAAAAAGACTAATAAAAA
TTTAAATTTGACATTGGAAAATTTGAAGGCAAATAAAATGAATGAGAACG
CAGCCGAGGAAGTTGGCACAAATGACAACATATCAAAACAAGCCGGTGAT
TGGTTGAGAACACTGGAGAATGAAAATAAAGTCAACATAAACAAAAGAAA
GCCAGTTGTCGGAAGCATATCTAAAGACATGACATTCAAATCCAGTCAGA
CAGTTGATACGGCTTTCAAGCCATGTGAATCCTGTCATATCTCTCAAACT
TGTCTACGAGAATCTAGTTCTATACTTATGAAAGTCCTGAAACAAGAATC
ACAGCCATCATCACTAATGAAATTACAACATGAAATTCTGAATCTTGATT
GGTTAAGTGACAAAAAGATAATGCAAATAAAAGATTGTTTTGCTAAAGAT
TTAGACAAAGTCTGTGCAATTTATCAAAATATAAAACAGAAAGAAATAAA
AACGGTTACTGAATTATCAGATTGCCGGAATATGTGCAAGAATTTCACTG
AAGCTTTGGAGAAAGAAAAATGTGAAATGCTTGCTTCTGAAACCAAATTT
AGTCGACAAATACATGAATTCGGCGTTGAAAATGAAAAACTAACAAACAC
GATAAGCCAGTTGAAATTGCAAACTGCTTCATTGATGGAAGAAATTGAGT
TGAAGGATAAACAAATAAATCAAGACAGAGCGCAATTAAAACAACATATA
TTAGAAAAACAAAATATCAACGAAGAATTAGACAAACTCAAAGTGTCAAT
TTCCAATTTCAATGTCAACGCAACCGATCCATTCGAAGCTCTTGCCATTA
TCAAAAGGAAAATCTCCGACCTAACCGACAACATTTCCCAATTGAATTCT
ACCATCCAAAATCAAAAGTCCATCAACGAAAATTTGACATTGACAGAAAA
TGTAATCAAGAACAAGGAAGAAAAGTTAGTAAAGCGATTACAAAGTTTAA
CGGAACAGAAGCACAAGCTTGAAGAGAAAATAGACATTTTACAAGACCAA
GTAGAAAGTAATCAAGAAAGTATTCGTGCTCTAGAAAATGAAAGAAACTC
AATGTCTATGAAATTATCGAATCAAACTATTTTGATTGAGACAATTACTA
AAGCAAAAGATGAATTTAGGGTAAGAATTACTGAGCTTCAAAGTCAGTTG
GAAGGTATGCAACAGACGATTCTTGAAATAAATCAAGGAAAGGATTTATT
AGTTAATTATCCAGACCTTAATGGGCCCTTAGATAAATTTGTTATTGTTA
ATGTAGAAGGCTGATAAACGGTCGAAAAAGATATAGCGAGATGTTATACA
AAATATAGAAATCAGGAAATATTGAACAAGATCTCATAAATCAAATCAAA
TCAAACGCAGCTCGCATAAGTTTGCTGTCAGAGCAAAATCGGGATTTAGA
ACAAGCATTAGAAAAACTTAATCAAACTTATTCATCTAATAAAAGTATTA
TTTCAAATAGTAATGTAAAAGCAACCAACAATTTGTCCAATACAAGTGGT
TTACCCCCAAATGTTGCTAGTTTAGAGTTATCGAGACCTCATTCCAAAAT
GTCCCATGTGGGTCAGTCTATGCCCAAAAGACAAACTCATAGACAATCAA
CTTCCAGCAGACCTCCAAGCAGAGACAATATCGCATCACAAGGTTCAATT
ATTCAATGGTCAGTTTCTAACCAGAAACCATCTCATGCAAATGTAATATT
TGTTTGTGAAACATGCGGTCGTAGTTACCAACAAAAATCTGATTTGGATG
TTCATAAAGAATATTGCGCAGGTCGGCGACGAAGGAGTGAAC
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protein sequence of SMED30009257-orf-1

>SMED30009257-orf-1 ID=SMED30009257-orf-1|Name=SMED30009257-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=577bp
MSFLLGSEYCIQSLSNDVSDVQSCIKDIIFKVGRINSISWKFPDKFACDL
NIDEYLTNYKYNPNDSESNQISHIILLELIIDRVCLLLQLHCETIEKIVS
KDKLSNTNCKSDSKTKMMSPCLGLTSKKHWNKLCQLSIYIDNIQQEIGQA
KKTNKNLNLTLENLKANKMNENAAEEVGTNDNISKQAGDWLRTLENENKV
NINKRKPVVGSISKDMTFKSSQTVDTAFKPCESCHISQTCLRESSSILMK
VLKQESQPSSLMKLQHEILNLDWLSDKKIMQIKDCFAKDLDKVCAIYQNI
KQKEIKTVTELSDCRNMCKNFTEALEKEKCEMLASETKFSRQIHEFGVEN
EKLTNTISQLKLQTASLMEEIELKDKQINQDRAQLKQHILEKQNINEELD
KLKVSISNFNVNATDPFEALAIIKRKISDLTDNISQLNSTIQNQKSINEN
LTLTENVIKNKEEKLVKRLQSLTEQKHKLEEKIDILQDQVESNQESIRAL
ENERNSMSMKLSNQTILIETITKAKDEFRVRITELQSQLEGMQQTILEIN
QGKDLLVNYPDLNGPLDKFVIVNVEG*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000034epidermis
PLANA:0000099neuron
PLANA:0000418head
Vocabulary: INTERPRO
TermDefinition
IPR029681CCDC157
IPR013087Znf_C2H2_type
IPR007087Znf_C2H2
Vocabulary: molecular function
TermDefinition
GO:0003676nucleic acid binding
GO:0046872metal ion binding
GO:0003674molecular_function
Vocabulary: cellular component
TermDefinition
GO:0005575cellular_component
Vocabulary: biological process
TermDefinition
GO:0008150biological_process
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableCOILSCoilCoilcoord: 518..545
NoneNo IPR availableCOILSCoilCoilcoord: 350..412
NoneNo IPR availableCOILSCoilCoilcoord: 462..510
NoneNo IPR availableCOILSCoilCoilcoord: 420..447
NoneNo IPR availableCOILSCoilCoilcoord: 140..174
IPR029681Coiled-coil domain-containing protein 157PANTHERPTHR43696FAMILY NOT NAMEDcoord: 1..567