Protein kinase domain-containing protein
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30009210 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 10
Homology
BLAST of Protein kinase domain-containing protein vs. Ensembl Human
Match: ICK (intestinal cell kinase [Source:HGNC Symbol;Acc:HGNC:21219]) HSP 1 Score: 402.519 bits (1033), Expect = 8.755e-131 Identity = 186/327 (56.88%), Postives = 237/327 (72.48%), Query Frame = 3
Query: 87 MDKYNFVKQLGDGTYGSVILANVVGTSEKVAIKKMKKKFYSWDECLNLREVKSLRLLKHPNIIRLKEVIRERDCLYLIFEYMNQNLYELIKSRNKPFPEEAIRNIIWQVLEGLTYIHKEGYFHRDLKPENILCNSATQIKLADFGLARSTRSAPPFTDYVATRWCLISLFFTVV*PCFDKPCDFRIHILFNSFLFRYRAPEVLLRSVNYNSPIDIFAVGCIMAELYTFRPLFPGSSEIDMIYKICCVLGTPNKNDWPEGQKLAGTMNFKFPTVTSTNLSVLIPSASRDAIKIMLEMISWNPKNRPTSKDSLQYDYFKTNGQRSGQIT 1067
M++Y ++QLGDGTYGSV+L + + E +AIKKMK+KFYSW+EC+NLREVKSL+ L H N+++LKEVIRE D LY IFEYM +NLY+LIK RNK FPE AIRNI++Q+L+GL +IHK G+FHRDLKPEN+LC +K+ADFGLAR RS PP+TDYV+TRW YRAPEVLLRS NY+SPID++AVGCIMAE+YT RPLFPG+SEID I+KIC VLGTP K DWPEG +L+ MNF++P NL LIP+AS +A++++ +M+ W+PK RPT+ +L+Y YF+ G G T
Sbjct: 1 MNRYTTIRQLGDGTYGSVLLGRSIESGELIAIKKMKRKFYSWEECMNLREVKSLKKLNHANVVKLKEVIRENDHLYFIFEYMKENLYQLIKERNKLFPESAIRNIMYQILQGLAFIHKHGFFHRDLKPENLLCMGPELVKIADFGLAREIRSKPPYTDYVSTRW--------------------------------YRAPEVLLRSTNYSSPIDVWAVGCIMAEVYTLRPLFPGASEIDTIFKICQVLGTPKKTDWPEGYQLSSAMNFRWPQCVPNNLKTLIPNASSEAVQLLRDMLQWDPKKRPTASQALRYPYFQV-GHPLGSTT 294
BLAST of Protein kinase domain-containing protein vs. Ensembl Human
Match: ICK (intestinal cell kinase [Source:HGNC Symbol;Acc:HGNC:21219]) HSP 1 Score: 402.519 bits (1033), Expect = 8.755e-131 Identity = 186/327 (56.88%), Postives = 237/327 (72.48%), Query Frame = 3
Query: 87 MDKYNFVKQLGDGTYGSVILANVVGTSEKVAIKKMKKKFYSWDECLNLREVKSLRLLKHPNIIRLKEVIRERDCLYLIFEYMNQNLYELIKSRNKPFPEEAIRNIIWQVLEGLTYIHKEGYFHRDLKPENILCNSATQIKLADFGLARSTRSAPPFTDYVATRWCLISLFFTVV*PCFDKPCDFRIHILFNSFLFRYRAPEVLLRSVNYNSPIDIFAVGCIMAELYTFRPLFPGSSEIDMIYKICCVLGTPNKNDWPEGQKLAGTMNFKFPTVTSTNLSVLIPSASRDAIKIMLEMISWNPKNRPTSKDSLQYDYFKTNGQRSGQIT 1067
M++Y ++QLGDGTYGSV+L + + E +AIKKMK+KFYSW+EC+NLREVKSL+ L H N+++LKEVIRE D LY IFEYM +NLY+LIK RNK FPE AIRNI++Q+L+GL +IHK G+FHRDLKPEN+LC +K+ADFGLAR RS PP+TDYV+TRW YRAPEVLLRS NY+SPID++AVGCIMAE+YT RPLFPG+SEID I+KIC VLGTP K DWPEG +L+ MNF++P NL LIP+AS +A++++ +M+ W+PK RPT+ +L+Y YF+ G G T
Sbjct: 1 MNRYTTIRQLGDGTYGSVLLGRSIESGELIAIKKMKRKFYSWEECMNLREVKSLKKLNHANVVKLKEVIRENDHLYFIFEYMKENLYQLIKERNKLFPESAIRNIMYQILQGLAFIHKHGFFHRDLKPENLLCMGPELVKIADFGLAREIRSKPPYTDYVSTRW--------------------------------YRAPEVLLRSTNYSSPIDVWAVGCIMAEVYTLRPLFPGASEIDTIFKICQVLGTPKKTDWPEGYQLSSAMNFRWPQCVPNNLKTLIPNASSEAVQLLRDMLQWDPKKRPTASQALRYPYFQV-GHPLGSTT 294
BLAST of Protein kinase domain-containing protein vs. Ensembl Human
Match: MAK (male germ cell associated kinase [Source:HGNC Symbol;Acc:HGNC:6816]) HSP 1 Score: 396.356 bits (1017), Expect = 9.615e-131 Identity = 194/369 (52.57%), Postives = 258/369 (69.92%), Query Frame = 3
Query: 87 MDKYNFVKQLGDGTYGSVILANVVGTSEKVAIKKMKKKFYSWDECLNLREVKSLRLLKHPNIIRLKEVIRERDCLYLIFEYMNQNLYELIKSRNKPFPEEAIRNIIWQVLEGLTYIHKEGYFHRDLKPENILCNSATQIKLADFGLARSTRSAPPFTDYVATRWCLISLFFTVV*PCFDKPCDFRIHILFNSFLFRYRAPEVLLRSVNYNSPIDIFAVGCIMAELYTFRPLFPGSSEIDMIYKICCVLGTPNKNDWPEGQKLAGTMNFKFPTVTSTNLSVLIPSASRDAIKIMLEMISWNPKNRPTSKDSLQYDYFKTNGQRSGQITTKRPLTN-VQNTSNLNIDMPTINNIMTINQNKPKTDP-ILDK 1187
M++Y ++QLGDGTYGSV++ + E VAIK+MK+KFYSWDEC+NLREVKSL+ L H N+I+LKEVIRE D LY IFEYM +NLY+L+K RNK FPE IRNI++Q+L+GL +IHK G+FHRD+KPEN+LC +K+ADFGLAR RS PP+TDYV+TRW YRAPEVLLRS Y+SPID++AVG IMAELY RPLFPG+SE+D I+KIC VLGTP K+DWPEG +LA +MNF+FP NL LIP+AS +AI++M EM++W+PK RPT+ +L++ YF+ GQ G P +N +++ +LN + + + ++ + +PK P I+D+
Sbjct: 1 MNRYTTMRQLGDGTYGSVLMGKSNESGELVAIKRMKRKFYSWDECMNLREVKSLKKLNHANVIKLKEVIRENDHLYFIFEYMKENLYQLMKDRNKLFPESVIRNIMYQILQGLAFIHKHGFFHRDMKPENLLCMGPELVKIADFGLARELRSQPPYTDYVSTRW--------------------------------YRAPEVLLRSSVYSSPIDVWAVGSIMAELYMLRPLFPGTSEVDEIFKICQVLGTPKKSDWPEGYQLASSMNFRFPQCVPINLKTLIPNASNEAIQLMTEMLNWDPKKRPTASQALKHPYFQV-GQVLG------PSSNHLESKQSLNKQLQPLESKPSLVEVEPKPLPDIIDQ 330
BLAST of Protein kinase domain-containing protein vs. Ensembl Human
Match: MAK (male germ cell associated kinase [Source:HGNC Symbol;Acc:HGNC:6816]) HSP 1 Score: 395.201 bits (1014), Expect = 1.297e-128 Identity = 186/335 (55.52%), Postives = 239/335 (71.34%), Query Frame = 3
Query: 87 MDKYNFVKQLGDGTYGSVILANVVGTSEKVAIKKMKKKFYSWDECLNLREVKSLRLLKHPNIIRLKEVIRERDCLYLIFEYMNQNLYELIKSRNKPFPEEAIRNIIWQVLEGLTYIHKEGYFHRDLKPENILCNSATQIKLADFGLARSTRSAPPFTDYVATRWCLISLFFTVV*PCFDKPCDFRIHILFNSFLFRYRAPEVLLRSVNYNSPIDIFAVGCIMAELYTFRPLFPGSSEIDMIYKICCVLGTPNKNDWPEGQKLAGTMNFKFPTVTSTNLSVLIPSASRDAIKIMLEMISWNPKNRPTSKDSLQYDYFKTN---GQRSGQITTKRPL 1082
M++Y ++QLGDGTYGSV++ + E VAIK+MK+KFYSWDEC+NLREVKSL+ L H N+I+LKEVIRE D LY IFEYM +NLY+L+K RNK FPE IRNI++Q+L+GL +IHK G+FHRD+KPEN+LC +K+ADFGLAR RS PP+TDYV+TRW YRAPEVLLRS Y+SPID++AVG IMAELY RPLFPG+SE+D I+KIC VLGTP K+DWPEG +LA +MNF+FP NL LIP+AS +AI++M EM++W+PK RPT+ +L++ YF+ G S + +K+ L
Sbjct: 1 MNRYTTMRQLGDGTYGSVLMGKSNESGELVAIKRMKRKFYSWDECMNLREVKSLKKLNHANVIKLKEVIRENDHLYFIFEYMKENLYQLMKDRNKLFPESVIRNIMYQILQGLAFIHKHGFFHRDMKPENLLCMGPELVKIADFGLARELRSQPPYTDYVSTRW--------------------------------YRAPEVLLRSSVYSSPIDVWAVGSIMAELYMLRPLFPGTSEVDEIFKICQVLGTPKKSDWPEGYQLASSMNFRFPQCVPINLKTLIPNASNEAIQLMTEMLNWDPKKRPTASQALKHPYFQVGQVLGPSSNHLESKQSL 303
BLAST of Protein kinase domain-containing protein vs. Ensembl Human
Match: MAK (male germ cell associated kinase [Source:HGNC Symbol;Acc:HGNC:6816]) HSP 1 Score: 395.586 bits (1015), Expect = 3.196e-128 Identity = 186/335 (55.52%), Postives = 239/335 (71.34%), Query Frame = 3
Query: 87 MDKYNFVKQLGDGTYGSVILANVVGTSEKVAIKKMKKKFYSWDECLNLREVKSLRLLKHPNIIRLKEVIRERDCLYLIFEYMNQNLYELIKSRNKPFPEEAIRNIIWQVLEGLTYIHKEGYFHRDLKPENILCNSATQIKLADFGLARSTRSAPPFTDYVATRWCLISLFFTVV*PCFDKPCDFRIHILFNSFLFRYRAPEVLLRSVNYNSPIDIFAVGCIMAELYTFRPLFPGSSEIDMIYKICCVLGTPNKNDWPEGQKLAGTMNFKFPTVTSTNLSVLIPSASRDAIKIMLEMISWNPKNRPTSKDSLQYDYFKTN---GQRSGQITTKRPL 1082
M++Y ++QLGDGTYGSV++ + E VAIK+MK+KFYSWDEC+NLREVKSL+ L H N+I+LKEVIRE D LY IFEYM +NLY+L+K RNK FPE IRNI++Q+L+GL +IHK G+FHRD+KPEN+LC +K+ADFGLAR RS PP+TDYV+TRW YRAPEVLLRS Y+SPID++AVG IMAELY RPLFPG+SE+D I+KIC VLGTP K+DWPEG +LA +MNF+FP NL LIP+AS +AI++M EM++W+PK RPT+ +L++ YF+ G S + +K+ L
Sbjct: 1 MNRYTTMRQLGDGTYGSVLMGKSNESGELVAIKRMKRKFYSWDECMNLREVKSLKKLNHANVIKLKEVIRENDHLYFIFEYMKENLYQLMKDRNKLFPESVIRNIMYQILQGLAFIHKHGFFHRDMKPENLLCMGPELVKIADFGLARELRSQPPYTDYVSTRW--------------------------------YRAPEVLLRSSVYSSPIDVWAVGSIMAELYMLRPLFPGTSEVDEIFKICQVLGTPKKSDWPEGYQLASSMNFRFPQCVPINLKTLIPNASNEAIQLMTEMLNWDPKKRPTASQALKHPYFQVGQVLGPSSNHLESKQSL 303
BLAST of Protein kinase domain-containing protein vs. Ensembl Celegans
Match: dyf-5 (Serine/threonine-protein kinase dyf-5 [Source:UniProtKB/Swiss-Prot;Acc:B3WFY8]) HSP 1 Score: 388.652 bits (997), Expect = 5.393e-128 Identity = 173/348 (49.71%), Postives = 246/348 (70.69%), Query Frame = 3
Query: 72 NCITIMDKYNFVKQLGDGTYGSVILANVVGTSEKVAIKKMKKKFYSWDECLNLREVKSLRLLKHPNIIRLKEVIRERDCLYLIFEYMNQNLYELIKSRNKPFPEEAIRNIIWQVLEGLTYIHKEGYFHRDLKPENILCNSATQIKLADFGLARSTRSAPPFTDYVATRWCLISLFFTVV*PCFDKPCDFRIHILFNSFLFRYRAPEVLLRSVNYNSPIDIFAVGCIMAELYTFRPLFPGSSEIDMIYKICCVLGTPNKNDWPEGQKLAGTMNFKFPTVTSTNLSVLIPSASRDAIKIMLEMISWNPKNRPTSKDSLQYDYFKTNGQRSGQITTKRPLTNVQNTSNLNI 1115
+ + + D+Y K+LGDGT+G V+LA + T ++VAIK+MKKKFYSW+E ++LREVKSL+ L HPNII+L+EVIRE D LY +FE+M +NLYEL+K R++ FPE IRNII+QVL+GL ++HK G+FHRD+KPENI+CN +K+ADFGLAR RS PP+TDYV+TRW YRAPE+LLRS +YNSPID++A+GCIMAELY RPLFPG+SE+D ++KI +LGTPNK++WPEG +LA MNF+F V +T + ++ + S++ +K+M++M+ WNP+ RP + SL+Y YF+ + + ++ +++ TS ++
Sbjct: 3 SAVKLADRYLMTKRLGDGTFGEVMLAKKIDTGDRVAIKRMKKKFYSWEEAMSLREVKSLKKLNHPNIIKLREVIRENDILYFVFEFMQENLYELMKDRDRYFPESVIRNIIYQVLQGLAFMHKNGFFHRDMKPENIMCNGTELVKIADFGLAREIRSKPPYTDYVSTRW--------------------------------YRAPEILLRSTSYNSPIDMWALGCIMAELYILRPLFPGTSEMDQLFKIISILGTPNKDEWPEGYQLASAMNFRFQQVVATPMEQVVNTISKEGMKLMMDMMLWNPEKRPNANQSLRYKYFQVAEKLGAPVVSQPAPGSIRKTSAASV 318
BLAST of Protein kinase domain-containing protein vs. Ensembl Celegans
Match: dyf-5 (Serine/threonine-protein kinase dyf-5 [Source:UniProtKB/Swiss-Prot;Acc:B3WFY8]) HSP 1 Score: 389.037 bits (998), Expect = 8.434e-128 Identity = 173/348 (49.71%), Postives = 246/348 (70.69%), Query Frame = 3
Query: 72 NCITIMDKYNFVKQLGDGTYGSVILANVVGTSEKVAIKKMKKKFYSWDECLNLREVKSLRLLKHPNIIRLKEVIRERDCLYLIFEYMNQNLYELIKSRNKPFPEEAIRNIIWQVLEGLTYIHKEGYFHRDLKPENILCNSATQIKLADFGLARSTRSAPPFTDYVATRWCLISLFFTVV*PCFDKPCDFRIHILFNSFLFRYRAPEVLLRSVNYNSPIDIFAVGCIMAELYTFRPLFPGSSEIDMIYKICCVLGTPNKNDWPEGQKLAGTMNFKFPTVTSTNLSVLIPSASRDAIKIMLEMISWNPKNRPTSKDSLQYDYFKTNGQRSGQITTKRPLTNVQNTSNLNI 1115
+ + + D+Y K+LGDGT+G V+LA + T ++VAIK+MKKKFYSW+E ++LREVKSL+ L HPNII+L+EVIRE D LY +FE+M +NLYEL+K R++ FPE IRNII+QVL+GL ++HK G+FHRD+KPENI+CN +K+ADFGLAR RS PP+TDYV+TRW YRAPE+LLRS +YNSPID++A+GCIMAELY RPLFPG+SE+D ++KI +LGTPNK++WPEG +LA MNF+F V +T + ++ + S++ +K+M++M+ WNP+ RP + SL+Y YF+ + + ++ +++ TS ++
Sbjct: 3 SAVKLADRYLMTKRLGDGTFGEVMLAKKIDTGDRVAIKRMKKKFYSWEEAMSLREVKSLKKLNHPNIIKLREVIRENDILYFVFEFMQENLYELMKDRDRYFPESVIRNIIYQVLQGLAFMHKNGFFHRDMKPENIMCNGTELVKIADFGLAREIRSKPPYTDYVSTRW--------------------------------YRAPEILLRSTSYNSPIDMWALGCIMAELYILRPLFPGTSEMDQLFKIISILGTPNKDEWPEGYQLASAMNFRFQQVVATPMEQVVNTISKEGMKLMMDMMLWNPEKRPNANQSLRYKYFQVAEKLGAPVVSQPAPGSIRKTSAASV 318
BLAST of Protein kinase domain-containing protein vs. Ensembl Celegans
Match: cdk-7 (Cyclin-dependent kinase 7 [Source:UniProtKB/Swiss-Prot;Acc:G5EFV5]) HSP 1 Score: 182.185 bits (461), Expect = 2.125e-51 Identity = 113/324 (34.88%), Postives = 169/324 (52.16%), Query Frame = 3
Query: 93 KYNFVKQLGDGTYGSVILANVVGTSEKVAIKKMKKKFYSWDECLN------LREVKSLRLLKHPNIIRLKEVIRERDCLYLIFEYMNQNLYELIKSRNKPFPEEAIRNIIWQVLEGLTYIHKEGYFHRDLKPENILCNSATQIKLADFGLARSTRSAP-PFTDYVATRWCLISLFFTVV*PCFDKPCDFRIHILFNSFLFRYRAPEVLLRSVNYNSPIDIFAVGCIMAELYTFRPLFPGSSEIDMIYKICCVLGTPNKNDWPEGQKLAGTMNFKFPTVTSTNLSVLIPSASRDAIKIMLEMISWNPKNRPTSKDSLQYDYFKTN 1043
+Y+ +K LG+G + +V LA + + E VAIKK+K S +E + +RE+K L+ + H NII L++VI R + L+F++M+ +L +IK + I+NI Q+L GL ++H HRDLKP N+L N ++KL DFGLAR S +T V TRW YRAPE+L + +Y IDI++VGCI+AEL P+FPG S+ID + KI +LG P WP ++ + K P L+ +A +D + +M M +++P R T SLQ +YF+T
Sbjct: 4 RYDTIKHLGEGQFANVYLAQDLESGECVAIKKIK--LGSREEAKDGINRTAIREIKLLKEIHHDNIIGLRDVIGHRTSIQLVFDFMDTDLEHVIKDKEIILMPAHIKNITMQMLLGLEFLHVHWILHRDLKPNNLLMNKMGRVKLTDFGLARFFGSPNRNYTHQVVTRW--------------------------------YRAPELLFGARSYGVGIDIWSVGCIIAELLLRNPIFPGESDIDQLVKIFNILGCPTPETWPNMTEMNSYVIIK-PQTEYMALNYYFSAAPQDLLDLMAGMWTFDPIKRLTCTQSLQMEYFRTQ 292
BLAST of Protein kinase domain-containing protein vs. Ensembl Celegans
Match: cdk-7 (Cyclin-dependent kinase 7 [Source:UniProtKB/Swiss-Prot;Acc:G5EFV5]) HSP 1 Score: 182.185 bits (461), Expect = 2.125e-51 Identity = 113/324 (34.88%), Postives = 169/324 (52.16%), Query Frame = 3
Query: 93 KYNFVKQLGDGTYGSVILANVVGTSEKVAIKKMKKKFYSWDECLN------LREVKSLRLLKHPNIIRLKEVIRERDCLYLIFEYMNQNLYELIKSRNKPFPEEAIRNIIWQVLEGLTYIHKEGYFHRDLKPENILCNSATQIKLADFGLARSTRSAP-PFTDYVATRWCLISLFFTVV*PCFDKPCDFRIHILFNSFLFRYRAPEVLLRSVNYNSPIDIFAVGCIMAELYTFRPLFPGSSEIDMIYKICCVLGTPNKNDWPEGQKLAGTMNFKFPTVTSTNLSVLIPSASRDAIKIMLEMISWNPKNRPTSKDSLQYDYFKTN 1043
+Y+ +K LG+G + +V LA + + E VAIKK+K S +E + +RE+K L+ + H NII L++VI R + L+F++M+ +L +IK + I+NI Q+L GL ++H HRDLKP N+L N ++KL DFGLAR S +T V TRW YRAPE+L + +Y IDI++VGCI+AEL P+FPG S+ID + KI +LG P WP ++ + K P L+ +A +D + +M M +++P R T SLQ +YF+T
Sbjct: 4 RYDTIKHLGEGQFANVYLAQDLESGECVAIKKIK--LGSREEAKDGINRTAIREIKLLKEIHHDNIIGLRDVIGHRTSIQLVFDFMDTDLEHVIKDKEIILMPAHIKNITMQMLLGLEFLHVHWILHRDLKPNNLLMNKMGRVKLTDFGLARFFGSPNRNYTHQVVTRW--------------------------------YRAPELLFGARSYGVGIDIWSVGCIIAELLLRNPIFPGESDIDQLVKIFNILGCPTPETWPNMTEMNSYVIIK-PQTEYMALNYYFSAAPQDLLDLMAGMWTFDPIKRLTCTQSLQMEYFRTQ 292
BLAST of Protein kinase domain-containing protein vs. Ensembl Celegans
Match: cdk-7 (Cyclin-dependent kinase 7 [Source:UniProtKB/Swiss-Prot;Acc:G5EFV5]) HSP 1 Score: 182.185 bits (461), Expect = 2.125e-51 Identity = 113/324 (34.88%), Postives = 169/324 (52.16%), Query Frame = 3
Query: 93 KYNFVKQLGDGTYGSVILANVVGTSEKVAIKKMKKKFYSWDECLN------LREVKSLRLLKHPNIIRLKEVIRERDCLYLIFEYMNQNLYELIKSRNKPFPEEAIRNIIWQVLEGLTYIHKEGYFHRDLKPENILCNSATQIKLADFGLARSTRSAP-PFTDYVATRWCLISLFFTVV*PCFDKPCDFRIHILFNSFLFRYRAPEVLLRSVNYNSPIDIFAVGCIMAELYTFRPLFPGSSEIDMIYKICCVLGTPNKNDWPEGQKLAGTMNFKFPTVTSTNLSVLIPSASRDAIKIMLEMISWNPKNRPTSKDSLQYDYFKTN 1043
+Y+ +K LG+G + +V LA + + E VAIKK+K S +E + +RE+K L+ + H NII L++VI R + L+F++M+ +L +IK + I+NI Q+L GL ++H HRDLKP N+L N ++KL DFGLAR S +T V TRW YRAPE+L + +Y IDI++VGCI+AEL P+FPG S+ID + KI +LG P WP ++ + K P L+ +A +D + +M M +++P R T SLQ +YF+T
Sbjct: 4 RYDTIKHLGEGQFANVYLAQDLESGECVAIKKIK--LGSREEAKDGINRTAIREIKLLKEIHHDNIIGLRDVIGHRTSIQLVFDFMDTDLEHVIKDKEIILMPAHIKNITMQMLLGLEFLHVHWILHRDLKPNNLLMNKMGRVKLTDFGLARFFGSPNRNYTHQVVTRW--------------------------------YRAPELLFGARSYGVGIDIWSVGCIIAELLLRNPIFPGESDIDQLVKIFNILGCPTPETWPNMTEMNSYVIIK-PQTEYMALNYYFSAAPQDLLDLMAGMWTFDPIKRLTCTQSLQMEYFRTQ 292
BLAST of Protein kinase domain-containing protein vs. Ensembl Fly
Match: CG42366 (gene:FBgn0259712 transcript:FBtr0331633) HSP 1 Score: 368.622 bits (945), Expect = 3.742e-117 Identity = 166/316 (52.53%), Postives = 226/316 (71.52%), Query Frame = 3
Query: 87 MDKYNFVKQLGDGTYGSVILANVVGTSEKVAIKKMKKKFYSWDECLNLREVKSLRLLKHPNIIRLKEVIRERDCLYLIFEYMNQNLYELIKSRNKPFPEEAIRNIIWQVLEGLTYIHKEGYFHRDLKPENILCNSATQIKLADFGLARSTRSAPPFTDYVATRWCLISLFFTVV*PCFDKPCDFRIHILFNSFLFRYRAPEVLLRSVNYNSPIDIFAVGCIMAELYTFRPLFPGSSEIDMIYKICCVLGTPNKNDWPEGQKLAGTMNFKFPTVTSTNLSVLIPSASRDAIKIMLEMISWNPKNRPTSKDSLQYDYF 1034
M++Y + QLGDGTYG+V+L T EKVAIK+MK+K+YSW+E +NLREVKSL+ L HPNI++LKEVIRE D LY +FEYM +NLY++IK R+ PE +++I++QVL GL ++H+ G+FHRDLKPEN+LC+ IK+ADFGLAR RS PPFTDYV+TRW YRAPEVLL S NY S ID++A+GCIMAELYTFRPLFPGSSE+D ++KIC VLGTP+K+DWP+G +LA ++F++P LS ++ S++ + ++ +M++++P RPT++ SL+Y YF
Sbjct: 1 MNRYITLTQLGDGTYGTVVLGQRKDTGEKVAIKRMKRKYYSWEEAMNLREVKSLKKLSHPNIVKLKEVIRENDTLYFVFEYMKENLYQMIKDRDTHLPEPELKSILFQVLTGLAFMHRHGFFHRDLKPENLLCSGPDLIKIADFGLAREIRSRPPFTDYVSTRW--------------------------------YRAPEVLLHSTNYGSTIDLWAMGCIMAELYTFRPLFPGSSEVDQLFKICSVLGTPDKDDWPDGYRLASMIHFRYPDCIKVPLSSVVSRCSQNGLDLLEDMLAYDPDKRPTAQQSLKYPYF 284
BLAST of Protein kinase domain-containing protein vs. Ensembl Fly
Match: CG42366 (gene:FBgn0259712 transcript:FBtr0299965) HSP 1 Score: 368.237 bits (944), Expect = 5.454e-117 Identity = 166/316 (52.53%), Postives = 226/316 (71.52%), Query Frame = 3
Query: 87 MDKYNFVKQLGDGTYGSVILANVVGTSEKVAIKKMKKKFYSWDECLNLREVKSLRLLKHPNIIRLKEVIRERDCLYLIFEYMNQNLYELIKSRNKPFPEEAIRNIIWQVLEGLTYIHKEGYFHRDLKPENILCNSATQIKLADFGLARSTRSAPPFTDYVATRWCLISLFFTVV*PCFDKPCDFRIHILFNSFLFRYRAPEVLLRSVNYNSPIDIFAVGCIMAELYTFRPLFPGSSEIDMIYKICCVLGTPNKNDWPEGQKLAGTMNFKFPTVTSTNLSVLIPSASRDAIKIMLEMISWNPKNRPTSKDSLQYDYF 1034
M++Y + QLGDGTYG+V+L T EKVAIK+MK+K+YSW+E +NLREVKSL+ L HPNI++LKEVIRE D LY +FEYM +NLY++IK R+ PE +++I++QVL GL ++H+ G+FHRDLKPEN+LC+ IK+ADFGLAR RS PPFTDYV+TRW YRAPEVLL S NY S ID++A+GCIMAELYTFRPLFPGSSE+D ++KIC VLGTP+K+DWP+G +LA ++F++P LS ++ S++ + ++ +M++++P RPT++ SL+Y YF
Sbjct: 1 MNRYITLTQLGDGTYGTVVLGQRKDTGEKVAIKRMKRKYYSWEEAMNLREVKSLKKLSHPNIVKLKEVIRENDTLYFVFEYMKENLYQMIKDRDTHLPEPELKSILFQVLTGLAFMHRHGFFHRDLKPENLLCSGPDLIKIADFGLAREIRSRPPFTDYVSTRW--------------------------------YRAPEVLLHSTNYGSTIDLWAMGCIMAELYTFRPLFPGSSEVDQLFKICSVLGTPDKDDWPDGYRLASMIHFRYPDCIKVPLSSVVSRCSQNGLDLLEDMLAYDPDKRPTAQQSLKYPYF 284
BLAST of Protein kinase domain-containing protein vs. Ensembl Fly
Match: Cdk2 (gene:FBgn0004107 transcript:FBtr0083922) HSP 1 Score: 186.037 bits (471), Expect = 6.215e-53 Identity = 110/322 (34.16%), Postives = 183/322 (56.83%), Query Frame = 3
Query: 81 TIMDKYNFVKQLGDGTYGSVILANVVGTSEKVAIKKMKKKFYSWD-ECLNLREVKSLRLLKHPNIIRLKEVIRERDCLYLIFEYMNQNLYELIKSRNKPFPEEAIRNIIWQVLEGLTYIHKEGYFHRDLKPENILCNSATQIKLADFGLARSTRSAP--PFTDYVATRWCLISLFFTVV*PCFDKPCDFRIHILFNSFLFRYRAPEVLLRSVNYNSPIDIFAVGCIMAELYTFRPLFPGSSEIDMIYKICCVLGTPNKNDWPEGQKLAGTMNFKFPTVTSTNLSVLIPSASRDAIKIMLEMISWNPKNRPTSKDSLQYDYFK 1037
TI+D + +++G+GTYG V A T + VA+KK++ + + +RE+ L+ LKHPN+++L +V+ + LY+IFEY+N +L +L+ + F + I++ + Q+L+ + + H HRDLKP+N+L ++A +IKLADFGLAR+ + P +T V T W YRAPE+LL + Y++ +DI+++GCI +E+ R LFPG SEID +Y+I L TP++ +WP +L KFP TN+ P +A ++++ M+ ++P R ++KD+LQ+ YF+
Sbjct: 3 TILDNFQRAEKIGEGTYGIVYKARSNSTGQDVALKKIRLEGETEGVPSTAIREISLLKNLKHPNVVQLFDVVISGNNLYMIFEYLNMDLKKLMDKKKDVFTPQLIKSYMHQILDAVGFCHTNRILHRDLKPQNLLVDTAGKIKLADFGLARAF-NVPMRAYTHEVVTLW--------------------------------YRAPEILLGTKFYSTGVDIWSLGCIFSEMIMRRSLFPGDSEIDQLYRIFRTLSTPDETNWPGVTQLPD-FKTKFPRWEGTNMPQ--PITEHEAHELIMSMLCYDPNLRISAKDALQHAYFR 288
BLAST of Protein kinase domain-containing protein vs. Ensembl Fly
Match: Cdk2 (gene:FBgn0004107 transcript:FBtr0300447) HSP 1 Score: 186.037 bits (471), Expect = 6.215e-53 Identity = 110/322 (34.16%), Postives = 183/322 (56.83%), Query Frame = 3
Query: 81 TIMDKYNFVKQLGDGTYGSVILANVVGTSEKVAIKKMKKKFYSWD-ECLNLREVKSLRLLKHPNIIRLKEVIRERDCLYLIFEYMNQNLYELIKSRNKPFPEEAIRNIIWQVLEGLTYIHKEGYFHRDLKPENILCNSATQIKLADFGLARSTRSAP--PFTDYVATRWCLISLFFTVV*PCFDKPCDFRIHILFNSFLFRYRAPEVLLRSVNYNSPIDIFAVGCIMAELYTFRPLFPGSSEIDMIYKICCVLGTPNKNDWPEGQKLAGTMNFKFPTVTSTNLSVLIPSASRDAIKIMLEMISWNPKNRPTSKDSLQYDYFK 1037
TI+D + +++G+GTYG V A T + VA+KK++ + + +RE+ L+ LKHPN+++L +V+ + LY+IFEY+N +L +L+ + F + I++ + Q+L+ + + H HRDLKP+N+L ++A +IKLADFGLAR+ + P +T V T W YRAPE+LL + Y++ +DI+++GCI +E+ R LFPG SEID +Y+I L TP++ +WP +L KFP TN+ P +A ++++ M+ ++P R ++KD+LQ+ YF+
Sbjct: 3 TILDNFQRAEKIGEGTYGIVYKARSNSTGQDVALKKIRLEGETEGVPSTAIREISLLKNLKHPNVVQLFDVVISGNNLYMIFEYLNMDLKKLMDKKKDVFTPQLIKSYMHQILDAVGFCHTNRILHRDLKPQNLLVDTAGKIKLADFGLARAF-NVPMRAYTHEVVTLW--------------------------------YRAPEILLGTKFYSTGVDIWSLGCIFSEMIMRRSLFPGDSEIDQLYRIFRTLSTPDETNWPGVTQLPD-FKTKFPRWEGTNMPQ--PITEHEAHELIMSMLCYDPNLRISAKDALQHAYFR 288
BLAST of Protein kinase domain-containing protein vs. Ensembl Fly
Match: Cdk2 (gene:FBgn0004107 transcript:FBtr0083921) HSP 1 Score: 186.037 bits (471), Expect = 6.215e-53 Identity = 110/322 (34.16%), Postives = 183/322 (56.83%), Query Frame = 3
Query: 81 TIMDKYNFVKQLGDGTYGSVILANVVGTSEKVAIKKMKKKFYSWD-ECLNLREVKSLRLLKHPNIIRLKEVIRERDCLYLIFEYMNQNLYELIKSRNKPFPEEAIRNIIWQVLEGLTYIHKEGYFHRDLKPENILCNSATQIKLADFGLARSTRSAP--PFTDYVATRWCLISLFFTVV*PCFDKPCDFRIHILFNSFLFRYRAPEVLLRSVNYNSPIDIFAVGCIMAELYTFRPLFPGSSEIDMIYKICCVLGTPNKNDWPEGQKLAGTMNFKFPTVTSTNLSVLIPSASRDAIKIMLEMISWNPKNRPTSKDSLQYDYFK 1037
TI+D + +++G+GTYG V A T + VA+KK++ + + +RE+ L+ LKHPN+++L +V+ + LY+IFEY+N +L +L+ + F + I++ + Q+L+ + + H HRDLKP+N+L ++A +IKLADFGLAR+ + P +T V T W YRAPE+LL + Y++ +DI+++GCI +E+ R LFPG SEID +Y+I L TP++ +WP +L KFP TN+ P +A ++++ M+ ++P R ++KD+LQ+ YF+
Sbjct: 3 TILDNFQRAEKIGEGTYGIVYKARSNSTGQDVALKKIRLEGETEGVPSTAIREISLLKNLKHPNVVQLFDVVISGNNLYMIFEYLNMDLKKLMDKKKDVFTPQLIKSYMHQILDAVGFCHTNRILHRDLKPQNLLVDTAGKIKLADFGLARAF-NVPMRAYTHEVVTLW--------------------------------YRAPEILLGTKFYSTGVDIWSLGCIFSEMIMRRSLFPGDSEIDQLYRIFRTLSTPDETNWPGVTQLPD-FKTKFPRWEGTNMPQ--PITEHEAHELIMSMLCYDPNLRISAKDALQHAYFR 288
BLAST of Protein kinase domain-containing protein vs. Ensembl Zebrafish
Match: mak (male germ cell-associated kinase [Source:ZFIN;Acc:ZDB-GENE-030131-7279]) HSP 1 Score: 390.578 bits (1002), Expect = 2.922e-126 Identity = 183/333 (54.95%), Postives = 236/333 (70.87%), Query Frame = 3
Query: 87 MDKYNFVKQLGDGTYGSVILANVVGTSEKVAIKKMKKKFYSWDECLNLREVKSLRLLKHPNIIRLKEVIRERDCLYLIFEYMNQNLYELIKSRNKPFPEEAIRNIIWQVLEGLTYIHKEGYFHRDLKPENILCNSATQIKLADFGLARSTRSAPPFTDYVATRWCLISLFFTVV*PCFDKPCDFRIHILFNSFLFRYRAPEVLLRSVNYNSPIDIFAVGCIMAELYTFRPLFPGSSEIDMIYKICCVLGTPNKNDWPEGQKLAGTMNFKFPTVTSTNLSVLIPSASRDAIKIMLEMISWNPKNRPTSKDSLQYDYFKTNGQRSGQITTKRPLT 1085
M++Y +KQLGDGTYGSV++ + E VAIK+MK+KFYSW+EC+NLREVKSL+ L H N+++LKEVIRE D LY +FEYM +NLY+L+K R K FPE IRNI +Q+L+GL++IHK G+FHRD+KPEN+LC +K+ADFGLAR RS PP+TDYV+TRW YRAPEVLLRS Y+SPIDI+AVGCIMAELYT RPLFPG+SE+D I+KIC VLGT K+DWPEG +LA MNF+FP T L LIP+A+ +A+ IM +++ W+PK RP++ +L+Y YF+ GQ+ RP+T
Sbjct: 1 MNRYTTLKQLGDGTYGSVLMGKSNESGELVAIKRMKRKFYSWEECMNLREVKSLKKLNHANVVKLKEVIRENDHLYFVFEYMKENLYQLMKDRTKLFPESVIRNISFQILQGLSFIHKHGFFHRDMKPENLLCMGPELVKIADFGLAREIRSRPPYTDYVSTRW--------------------------------YRAPEVLLRSPVYSSPIDIWAVGCIMAELYTLRPLFPGNSEVDEIFKICQVLGTVKKSDWPEGHQLASAMNFRFPQCVPTPLKTLIPNATNEALDIMRDLLQWDPKKRPSAVKALRYPYFQV-----GQLLGPRPMT 296
BLAST of Protein kinase domain-containing protein vs. Ensembl Zebrafish
Match: mak (male germ cell-associated kinase [Source:ZFIN;Acc:ZDB-GENE-030131-7279]) HSP 1 Score: 384.415 bits (986), Expect = 5.952e-124 Identity = 183/334 (54.79%), Postives = 235/334 (70.36%), Query Frame = 3
Query: 87 MDKYNFVKQLGDGTYGSVILANVVGTSEKVAIKKMKKKFYSWDECLNLREVKSLRLLKHPNIIRLKEVIRERDCLYLIFEYMNQNLYELIKSR-NKPFPEEAIRNIIWQVLEGLTYIHKEGYFHRDLKPENILCNSATQIKLADFGLARSTRSAPPFTDYVATRWCLISLFFTVV*PCFDKPCDFRIHILFNSFLFRYRAPEVLLRSVNYNSPIDIFAVGCIMAELYTFRPLFPGSSEIDMIYKICCVLGTPNKNDWPEGQKLAGTMNFKFPTVTSTNLSVLIPSASRDAIKIMLEMISWNPKNRPTSKDSLQYDYFKTNGQRSGQITTKRPLT 1085
M++Y +KQLGDGTYGSV++ + E VAIK+MK+KFYSW+EC+NLREVKSL+ L H N+++LKEVIRE D LY +FEYM +NLY+L+K R NK F E IRNI++QVL GL ++HK G+FHRD+KPEN+LC +K+ADFGLAR RS PP+TDYV+TRW YRAPEVLLRS Y+SPIDI+AVGCIMAELYT RPLFPG+SE+D I+KIC VLGT K+DWPEG +LA MNF+FP T L LIP+A+ +A+ IM +++ W+PK RP++ +L+Y YF+ GQ+ RP+T
Sbjct: 1 MNRYTTLKQLGDGTYGSVLMGKSNESGELVAIKRMKRKFYSWEECMNLREVKSLKKLNHANVVKLKEVIRENDHLYFVFEYMKENLYQLMKDRENKMFTENEIRNIMFQVLSGLAFVHKHGFFHRDMKPENLLCMGPELVKIADFGLAREIRSRPPYTDYVSTRW--------------------------------YRAPEVLLRSPVYSSPIDIWAVGCIMAELYTLRPLFPGNSEVDEIFKICQVLGTVKKSDWPEGHQLASAMNFRFPQCVPTPLKTLIPNATNEALDIMRDLLQWDPKKRPSAVKALRYPYFQV-----GQLLGPRPMT 297
BLAST of Protein kinase domain-containing protein vs. Ensembl Zebrafish
Match: CABZ01067557.1 (cyclin-dependent kinase 16-like [Source:NCBI gene;Acc:100536316]) HSP 1 Score: 193.741 bits (491), Expect = 1.057e-53 Identity = 104/328 (31.71%), Postives = 177/328 (53.96%), Query Frame = 3
Query: 87 MDKYNFVKQLGDGTYGSVILANVVGTSEKVAIKKMKKKFYSWDECLNLREVKSLRLLKHPNIIRLKEVIRERDCLYLIFEYMNQNLYELIKSRNKPFPEEAIRNIIWQVLEGLTYIHKEGYFHRDLKPENILCNSATQIKLADFGLARSTRSAP--PFTDYVATRWCLISLFFTVV*PCFDKPCDFRIHILFNSFLFRYRAPEVLLRSVNYNSPIDIFAVGCIMAELYTFRPLFPGSSEIDMIYKICCVLGTPNKNDWPEGQKLAGTMNFKFPTVTSTNLSVLIPSASRDAIKIMLEMISWNPKNRPTSKDSLQYDYFKTNGQRSGQI 1064
++ Y + +LG+GTY +V T VA+K+++ ++ C +REV L+ LKH NI+ L ++I CL L+FEY++++L + + + ++ ++Q+L GL Y H + HRDLKP+N+L N ++KLADFGLAR+ +S P F++ V T W YR P+VLL S Y++PIDI+ VGCI E+ T RPLFPGS+ D ++ I +LG+P ++ WPE ++++FP L P + D ++ +++ ++ + R +++ +L++ YF+ G + Q+
Sbjct: 130 LETYIKLDKLGEGTYATVYKGRSKLTDNLVALKEIRLEYEEGAPCTAIREVSLLKNLKHANIVTLHDIIHTEKCLTLVFEYLDRDLKQYLDNCGSIMSIYNVKIFLFQLLRGLAYCHSQKVLHRDLKPQNLLINDKGELKLADFGLARA-KSVPTKTFSNEVVTLW--------------------------------YRPPDVLLGSTEYSTPIDIWGVGCIFYEMITGRPLFPGSTVEDELHLIFRILGSPTEDSWPEAYSNENFLSYRFPQYDGEPLVTHAPRITNDGHDLLCQLLQFDARRRVSAEAALRHVYFRDLGDKVHQL 424
BLAST of Protein kinase domain-containing protein vs. Ensembl Zebrafish
Match: cdk2 (cyclin-dependent kinase 2 [Source:ZFIN;Acc:ZDB-GENE-040426-2741]) HSP 1 Score: 187.578 bits (475), Expect = 1.712e-53 Identity = 107/320 (33.44%), Postives = 177/320 (55.31%), Query Frame = 3
Query: 87 MDKYNFVKQLGDGTYGSVILANVVGTSEKVAIKKMKKKFYSWD-ECLNLREVKSLRLLKHPNIIRLKEVIRERDCLYLIFEYMNQNLYELIKSRN-KPFPEEAIRNIIWQVLEGLTYIHKEGYFHRDLKPENILCNSATQIKLADFGLARS-TRSAPPFTDYVATRWCLISLFFTVV*PCFDKPCDFRIHILFNSFLFRYRAPEVLLRSVNYNSPIDIFAVGCIMAELYTFRPLFPGSSEIDMIYKICCVLGTPNKNDWPEGQKLAGTMNFKFPTVTSTNLSVLIPSASRDAIKIMLEMISWNPKNRPTSKDSLQYDYFK 1037
M+ + V+++G+GTYG V A T E VA+KK++ + +RE+ L+ L HPNI++L++VI + LYL+FE+++Q+L + S + +++ ++Q+L+GL + H HRDLKP+N+L N+ +IKLADFGLAR+ +T V T W YRAPE+LL Y++ +DI+++GCI AE+ T R LFPG SEID +++I LGTP+++ WP G FP +LS ++P D ++ +M++++P R ++K++L + +F+
Sbjct: 1 MESFQKVEKIGEGTYGVVYKAKNKVTGETVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLRDVIHTENKLYLVFEFLHQDLKRFMDSTSVSGISLPLVKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINAQGEIKLADFGLARAFGVPVRTYTHEVVTLW--------------------------------YRAPEILLGCKYYSTAVDIWSLGCIFAEMITRRALFPGDSEIDQLFRIFRTLGTPDESIWP-GVTSMPDYKPSFPKWARQDLSKVVPPLDEDGRDLLGQMLTYDPNKRISAKNALVHRFFR 287
BLAST of Protein kinase domain-containing protein vs. Ensembl Zebrafish
Match: cdk1 (cyclin-dependent kinase 1 [Source:ZFIN;Acc:ZDB-GENE-010320-1]) HSP 1 Score: 181.8 bits (460), Expect = 2.314e-51 Identity = 106/322 (32.92%), Postives = 180/322 (55.90%), Query Frame = 3
Query: 87 MDKYNFVKQLGDGTYGSVILANVVGTSEKVAIKKMKKKFYSWDECL---NLREVKSLRLLKHPNIIRLKEVIRERDCLYLIFEYMNQNLYELIKS--RNKPFPEEAIRNIIWQVLEGLTYIHKEGYFHRDLKPENILCNSATQIKLADFGLARS-TRSAPPFTDYVATRWCLISLFFTVV*PCFDKPCDFRIHILFNSFLFRYRAPEVLLRSVNYNSPIDIFAVGCIMAELYTFRPLFPGSSEIDMIYKICCVLGTPNKNDWPEGQKLAGTMNFKFPTVTSTNLSVLIPSASRDAIKIMLEMISWNPKNRPTSKDSLQYDYF 1034
MD Y ++++G+GTYG V T + VA+KK++ S +E + +RE+ L+ L+HPN++RL +V+ + LYL+FE+++ +L + + S + +++ ++Q+LEG+ + H HRDLKP+N+L ++ IKLADFGLAR+ +T V T W YRAPEVLL + Y++P+D++++G I AEL T +PLF G SEID +++I LGTPN WP+ + L N FP S NL+ + + ++ I ++++M+ ++P R +++ ++ + YF
Sbjct: 1 MDDYLKIEKIGEGTYGVVYKGRNKTTGQVVAMKKIR--LESEEEGVPSTAVREISLLKELQHPNVVRLLDVLMQESKLYLVFEFLSMDLKKYLDSIPSGEFMDPMLVKSYLYQILEGILFCHCRRVLHRDLKPQNLLIDNKGVIKLADFGLARAFGVPVRVYTHEVVTLW--------------------------------YRAPEVLLGASRYSTPVDLWSIGTIFAELATKKPLFHGDSEIDQLFRIFRTLGTPNNEVWPDVESLPDYKN-TFPKWKSGNLANTVKNLDKNGIDLLMKMLIYDPPKRISARQAMTHPYF 287
BLAST of Protein kinase domain-containing protein vs. Ensembl Xenopus
Match: dnajc3 (DnaJ heat shock protein family (Hsp40) member C3 [Source:Xenbase;Acc:XB-GENE-997043]) HSP 1 Score: 410.223 bits (1053), Expect = 7.204e-134 Identity = 227/535 (42.43%), Postives = 306/535 (57.20%), Query Frame = 3
Query: 87 MDKYNFVKQLGDGTYGSVILANVVGTSEKVAIKKMKKKFYSWDECLNLREVKSLRLLKHPNIIRLKEVIRERDCLYLIFEYMNQNLYELIKSRNKPFPEEAIRNIIWQVLEGLTYIHKEGYFHRDLKPENILCNSATQIKLADFGLARSTRSAPPFTDYVATRWCLISLFFTVV*PCFDKPCDFRIHILFNSFLFRYRAPEVLLRSVNYNSPIDIFAVGCIMAELYTFRPLFPGSSEIDMIYKICCVLGTPNKNDWPEGQKLAGTMNFKFPTVTSTNLSVLIPSASRDAIKIMLEMISWNPKNRPTSKDSLQYDYFKTNGQRSGQ----ITTKRPLTNVQNTSNLN----IDMPTINNIMTINQNKPKTDPILDKSDRRKWAPMEFSDDWDFDIGT--------SKNHFSKPVKNEPNPSEIK------------RQKAFDEFDFDMSFIAEMNSKSPQRRKSTKRESXXXXXXLESINNKSKITQKNDITSGKENMGPFVSGTQRRPSVNKGSASSFYKSNARYHVGMNPRNSG 1607
M++Y +KQLGDGTYGSV++ + E VAIK+MK+KFYSW+EC+NLREVKSL+ L H N+++LKEVIRE D L+ +FEYM +NLY+L+K RNK FPE IRNI++Q+L+GL +IHK G+FHRD+KPEN+LC +K+ADFGL R RS PP+TDYV+TRW YRAPEVLLRS +Y+SPIDI+AVG IMAELYT RPLFPG+SE+D I+KIC VLGTP KNDWPEG +LA +MNF+FP NL LIP+AS DA+ +M + + W+PK RPT+ +L++ YF+ GQ G + K+PL M + ++ + ++ P T P ++ ++ P + +DD T SK KPV N P S + + ++DE D D SK P + E+ S + I+ EN G + G +R + SA Y +RY GMNP+N+G
Sbjct: 1 MNRYTTMKQLGDGTYGSVLMGRSNESGELVAIKRMKRKFYSWEECMNLREVKSLKKLNHANVVKLKEVIRENDQLFFVFEYMKENLYQLMKDRNKLFPESVIRNIMYQILQGLAFIHKHGFFHRDMKPENLLCMGPELVKIADFGLVRELRSQPPYTDYVSTRW--------------------------------YRAPEVLLRSSSYSSPIDIWAVGSIMAELYTLRPLFPGTSEVDQIFKICQVLGTPKKNDWPEGYQLAASMNFRFPQCVPINLKTLIPNASEDALSLMRDTMQWDPKKRPTASQALRHPYFQV-GQALGPPVQYVEQKKPLNKAPKPQEPRPIYVTKMQSSSSSEILEKSSPDTPPATNRPLQQIQVP-QSTDDIQLPSKTQQVVLPSISKTISPKPVANGPQTSAVSIKHGRRRWGQSVVKDSWDEIDTDFGI---SYSKKP-----------TMALAKENKPEDSLFGLSDPISIVDENKGSSIVGMKRTDTSQTTSAKQHYLRQSRYLPGMNPKNAG 487
BLAST of Protein kinase domain-containing protein vs. Ensembl Xenopus
Match: ICK (intestinal cell (MAK-like) kinase [Source:NCBI gene;Acc:100498050]) HSP 1 Score: 401.749 bits (1031), Expect = 5.441e-133 Identity = 193/324 (59.57%), Postives = 235/324 (72.53%), Query Frame = 3
Query: 87 MDKYNFVKQLGDGTYGSVILANVVGTSEKVAIKKMKKKFYSWDECLNLREVKSLRLLKHPNIIRLKEVIRERDCLYLIFEYMNQNLYELIKSRNKPFPEEAIRNIIWQVLEGLTYIHKEGYFHRDLKPENILCNSATQIKLADFGLARSTRSAPPFTDYVATRWCLISLFFTVV*PCFDKPCDFRIHILFNSFLFRYRAPEVLLRSVNYNSPIDIFAVGCIMAELYTFRPLFPGSSEIDMIYKICCVLGTPNKNDWPEGQKLAGTMNFKFPTVTSTNLSVLIPSASRDAIKIMLEMISWNPKNRPTSKDSLQYDYFKTNGQRSG 1058
M++Y VKQLGDGTYGSVIL V + E VAIKKMK+KFYSWDEC+NLREVKSL+ L H N+I+LKEVIRE + LY +FEYM +NLY+L+K RNK FPE IRNI++Q+L+GL YIHK G+FHRDLKPEN+LC +K+ADFGLAR TRS PP+TDYV+TRW YRAPEVLLR+ NYNSPIDI+AVGCIMAE+YT RPLFPGSSE+D I+KIC VLGTP KNDW EG +LA MNF++ +NL LIP+A D I++M +M+ W+PK RPT+ +L+Y YF+ GQ G
Sbjct: 1 MNRYTTVKQLGDGTYGSVILGRSVESGELVAIKKMKRKFYSWDECMNLREVKSLKKLNHANVIKLKEVIRENNQLYFVFEYMKENLYQLMKDRNKLFPESIIRNIMYQILQGLAYIHKYGFFHRDLKPENLLCMGPELVKIADFGLARETRSRPPYTDYVSTRW--------------------------------YRAPEVLLRATNYNSPIDIWAVGCIMAEIYTLRPLFPGSSEVDTIFKICQVLGTPKKNDWFEGFQLASAMNFRWAHCVPSNLKTLIPNACADGIQVMRDMLQWDPKKRPTASQALRYSYFQV-GQTLG 291
BLAST of Protein kinase domain-containing protein vs. Ensembl Xenopus
Match: ICK (intestinal cell (MAK-like) kinase [Source:NCBI gene;Acc:100498050]) HSP 1 Score: 403.29 bits (1035), Expect = 2.790e-132 Identity = 193/324 (59.57%), Postives = 235/324 (72.53%), Query Frame = 3
Query: 87 MDKYNFVKQLGDGTYGSVILANVVGTSEKVAIKKMKKKFYSWDECLNLREVKSLRLLKHPNIIRLKEVIRERDCLYLIFEYMNQNLYELIKSRNKPFPEEAIRNIIWQVLEGLTYIHKEGYFHRDLKPENILCNSATQIKLADFGLARSTRSAPPFTDYVATRWCLISLFFTVV*PCFDKPCDFRIHILFNSFLFRYRAPEVLLRSVNYNSPIDIFAVGCIMAELYTFRPLFPGSSEIDMIYKICCVLGTPNKNDWPEGQKLAGTMNFKFPTVTSTNLSVLIPSASRDAIKIMLEMISWNPKNRPTSKDSLQYDYFKTNGQRSG 1058
M++Y VKQLGDGTYGSVIL V + E VAIKKMK+KFYSWDEC+NLREVKSL+ L H N+I+LKEVIRE + LY +FEYM +NLY+L+K RNK FPE IRNI++Q+L+GL YIHK G+FHRDLKPEN+LC +K+ADFGLAR TRS PP+TDYV+TRW YRAPEVLLR+ NYNSPIDI+AVGCIMAE+YT RPLFPGSSE+D I+KIC VLGTP KNDW EG +LA MNF++ +NL LIP+A D I++M +M+ W+PK RPT+ +L+Y YF+ GQ G
Sbjct: 1 MNRYTTVKQLGDGTYGSVILGRSVESGELVAIKKMKRKFYSWDECMNLREVKSLKKLNHANVIKLKEVIRENNQLYFVFEYMKENLYQLMKDRNKLFPESIIRNIMYQILQGLAYIHKYGFFHRDLKPENLLCMGPELVKIADFGLARETRSRPPYTDYVSTRW--------------------------------YRAPEVLLRATNYNSPIDIWAVGCIMAEIYTLRPLFPGSSEVDTIFKICQVLGTPKKNDWFEGFQLASAMNFRWAHCVPSNLKTLIPNACADGIQVMRDMLQWDPKKRPTASQALRYSYFQV-GQTLG 291
BLAST of Protein kinase domain-containing protein vs. Ensembl Xenopus
Match: ICK (intestinal cell (MAK-like) kinase [Source:NCBI gene;Acc:100498050]) HSP 1 Score: 403.675 bits (1036), Expect = 2.346e-131 Identity = 193/324 (59.57%), Postives = 235/324 (72.53%), Query Frame = 3
Query: 87 MDKYNFVKQLGDGTYGSVILANVVGTSEKVAIKKMKKKFYSWDECLNLREVKSLRLLKHPNIIRLKEVIRERDCLYLIFEYMNQNLYELIKSRNKPFPEEAIRNIIWQVLEGLTYIHKEGYFHRDLKPENILCNSATQIKLADFGLARSTRSAPPFTDYVATRWCLISLFFTVV*PCFDKPCDFRIHILFNSFLFRYRAPEVLLRSVNYNSPIDIFAVGCIMAELYTFRPLFPGSSEIDMIYKICCVLGTPNKNDWPEGQKLAGTMNFKFPTVTSTNLSVLIPSASRDAIKIMLEMISWNPKNRPTSKDSLQYDYFKTNGQRSG 1058
M++Y VKQLGDGTYGSVIL V + E VAIKKMK+KFYSWDEC+NLREVKSL+ L H N+I+LKEVIRE + LY +FEYM +NLY+L+K RNK FPE IRNI++Q+L+GL YIHK G+FHRDLKPEN+LC +K+ADFGLAR TRS PP+TDYV+TRW YRAPEVLLR+ NYNSPIDI+AVGCIMAE+YT RPLFPGSSE+D I+KIC VLGTP KNDW EG +LA MNF++ +NL LIP+A D I++M +M+ W+PK RPT+ +L+Y YF+ GQ G
Sbjct: 1 MNRYTTVKQLGDGTYGSVILGRSVESGELVAIKKMKRKFYSWDECMNLREVKSLKKLNHANVIKLKEVIRENNQLYFVFEYMKENLYQLMKDRNKLFPESIIRNIMYQILQGLAYIHKYGFFHRDLKPENLLCMGPELVKIADFGLARETRSRPPYTDYVSTRW--------------------------------YRAPEVLLRATNYNSPIDIWAVGCIMAEIYTLRPLFPGSSEVDTIFKICQVLGTPKKNDWFEGFQLASAMNFRWAHCVPSNLKTLIPNACADGIQVMRDMLQWDPKKRPTASQALRYSYFQV-GQTLG 291
BLAST of Protein kinase domain-containing protein vs. Ensembl Xenopus
Match: dnajc3 (DnaJ heat shock protein family (Hsp40) member C3 [Source:Xenbase;Acc:XB-GENE-997043]) HSP 1 Score: 399.823 bits (1026), Expect = 5.640e-130 Identity = 226/536 (42.16%), Postives = 304/536 (56.72%), Query Frame = 3
Query: 87 MDKYNFVKQLGDGTYGSVILANVVGTSEKVAIKKMKKKFYSWDECLNLREVKSLRLLKHPNIIRLKEVIRERDCLYLIFEYMNQNLYELIKSR-NKPFPEEAIRNIIWQVLEGLTYIHKEGYFHRDLKPENILCNSATQIKLADFGLARSTRSAPPFTDYVATRWCLISLFFTVV*PCFDKPCDFRIHILFNSFLFRYRAPEVLLRSVNYNSPIDIFAVGCIMAELYTFRPLFPGSSEIDMIYKICCVLGTPNKNDWPEGQKLAGTMNFKFPTVTSTNLSVLIPSASRDAIKIMLEMISWNPKNRPTSKDSLQYDYFKTNGQRSGQ----ITTKRPLTNVQNTSNLN----IDMPTINNIMTINQNKPKTDPILDKSDRRKWAPMEFSDDWDFDIGT--------SKNHFSKPVKNEPNPSEIK------------RQKAFDEFDFDMSFIAEMNSKSPQRRKSTKRESXXXXXXLESINNKSKITQKNDITSGKENMGPFVSGTQRRPSVNKGSASSFYKSNARYHVGMNPRNSG 1607
M++Y +KQLGDGTYGSV++ + E VAIK+MK+KFYSW+EC+NLREVKSL+ L H N+++LKEVIRE D L+ +FEYM +NLY+L+K R NK F E IRNI++QVL GL ++HK G+FHRD+KPEN+LC +K+ADFGL R RS PP+TDYV+TRW YRAPEVLLRS +Y+SPIDI+AVG IMAELYT RPLFPG+SE+D I+KIC VLGTP KNDWPEG +LA +MNF+FP NL LIP+AS DA+ +M + + W+PK RPT+ +L++ YF+ GQ G + K+PL M + ++ + ++ P T P ++ ++ P + +DD T SK KPV N P S + + ++DE D D SK P + E+ S + I+ EN G + G +R + SA Y +RY GMNP+N+G
Sbjct: 1 MNRYTTMKQLGDGTYGSVLMGRSNESGELVAIKRMKRKFYSWEECMNLREVKSLKKLNHANVVKLKEVIRENDQLFFVFEYMKENLYQLMKDRENKMFTENEIRNIMFQVLSGLAFVHKHGFFHRDMKPENLLCMGPELVKIADFGLVRELRSQPPYTDYVSTRW--------------------------------YRAPEVLLRSSSYSSPIDIWAVGSIMAELYTLRPLFPGTSEVDQIFKICQVLGTPKKNDWPEGYQLAASMNFRFPQCVPINLKTLIPNASEDALSLMRDTMQWDPKKRPTASQALRHPYFQV-GQALGPPVQYVEQKKPLNKAPKPQEPRPIYVTKMQSSSSSEILEKSSPDTPPATNRPLQQIQVP-QSTDDIQLPSKTQQVVLPSISKTISPKPVANGPQTSAVSIKHGRRRWGQSVVKDSWDEIDTDFGI---SYSKKP-----------TMALAKENKPEDSLFGLSDPISIVDENKGSSIVGMKRTDTSQTTSAKQHYLRQSRYLPGMNPKNAG 488
BLAST of Protein kinase domain-containing protein vs. Ensembl Mouse
Match: Ick (intestinal cell kinase [Source:MGI Symbol;Acc:MGI:1934157]) HSP 1 Score: 402.134 bits (1032), Expect = 6.180e-132 Identity = 192/342 (56.14%), Postives = 244/342 (71.35%), Query Frame = 3
Query: 87 MDKYNFVKQLGDGTYGSVILANVVGTSEKVAIKKMKKKFYSWDECLNLREVKSLRLLKHPNIIRLKEVIRERDCLYLIFEYMNQNLYELIKSRNKPFPEEAIRNIIWQVLEGLTYIHKEGYFHRDLKPENILCNSATQIKLADFGLARSTRSAPPFTDYVATRWCLISLFFTVV*PCFDKPCDFRIHILFNSFLFRYRAPEVLLRSVNYNSPIDIFAVGCIMAELYTFRPLFPGSSEIDMIYKICCVLGTPNKNDWPEGQKLAGTMNFKFPTVTSTNLSVLIPSASRDAIKIMLEMISWNPKNRPTSKDSLQYDYFKTNGQRSGQIT--TKRPLTNVQNTSN 1106
M++Y +KQLGDGTYGSV+L + + E +AIKKMK+KFYSW+EC+NLREVKSL+ L H NI++LKEVIRE D LY IFEYM +NLY+LIK RNK FPE AIRNI++Q+L+GL +IHK G+FHRDLKPEN+LC +K+ADFGLAR RS PP+TDYV+TRW YRAPEVLLRS NY+SPIDI+AVGCIMAE+YT RPLFPG+SEID I+KIC VLGTP K DWPEG +L+ MNF +P NL LIP+AS +AI+++ +++ W+PK RPT+ +L+Y YF+ G G I+ + +P VQ+ +
Sbjct: 1 MNRYTTIKQLGDGTYGSVLLGRSIESGELIAIKKMKRKFYSWEECMNLREVKSLKKLNHANIVKLKEVIRENDHLYFIFEYMKENLYQLIKERNKLFPESAIRNIMYQILQGLAFIHKHGFFHRDLKPENLLCMGPELVKIADFGLAREIRSRPPYTDYVSTRW--------------------------------YRAPEVLLRSTNYSSPIDIWAVGCIMAEVYTLRPLFPGASEIDTIFKICQVLGTPKKTDWPEGYQLSSAMNFLWPQCIPNNLKTLIPNASSEAIQLLRDLLQWDPKKRPTASQALRYPYFQI-GHPLGIISKDSGKPQREVQDKTG 309
BLAST of Protein kinase domain-containing protein vs. Ensembl Mouse
Match: Ick (intestinal cell kinase [Source:MGI Symbol;Acc:MGI:1934157]) HSP 1 Score: 401.749 bits (1031), Expect = 1.427e-130 Identity = 192/342 (56.14%), Postives = 244/342 (71.35%), Query Frame = 3
Query: 87 MDKYNFVKQLGDGTYGSVILANVVGTSEKVAIKKMKKKFYSWDECLNLREVKSLRLLKHPNIIRLKEVIRERDCLYLIFEYMNQNLYELIKSRNKPFPEEAIRNIIWQVLEGLTYIHKEGYFHRDLKPENILCNSATQIKLADFGLARSTRSAPPFTDYVATRWCLISLFFTVV*PCFDKPCDFRIHILFNSFLFRYRAPEVLLRSVNYNSPIDIFAVGCIMAELYTFRPLFPGSSEIDMIYKICCVLGTPNKNDWPEGQKLAGTMNFKFPTVTSTNLSVLIPSASRDAIKIMLEMISWNPKNRPTSKDSLQYDYFKTNGQRSGQIT--TKRPLTNVQNTSN 1106
M++Y +KQLGDGTYGSV+L + + E +AIKKMK+KFYSW+EC+NLREVKSL+ L H NI++LKEVIRE D LY IFEYM +NLY+LIK RNK FPE AIRNI++Q+L+GL +IHK G+FHRDLKPEN+LC +K+ADFGLAR RS PP+TDYV+TRW YRAPEVLLRS NY+SPIDI+AVGCIMAE+YT RPLFPG+SEID I+KIC VLGTP K DWPEG +L+ MNF +P NL LIP+AS +AI+++ +++ W+PK RPT+ +L+Y YF+ G G I+ + +P VQ+ +
Sbjct: 1 MNRYTTIKQLGDGTYGSVLLGRSIESGELIAIKKMKRKFYSWEECMNLREVKSLKKLNHANIVKLKEVIRENDHLYFIFEYMKENLYQLIKERNKLFPESAIRNIMYQILQGLAFIHKHGFFHRDLKPENLLCMGPELVKIADFGLAREIRSRPPYTDYVSTRW--------------------------------YRAPEVLLRSTNYSSPIDIWAVGCIMAEVYTLRPLFPGASEIDTIFKICQVLGTPKKTDWPEGYQLSSAMNFLWPQCIPNNLKTLIPNASSEAIQLLRDLLQWDPKKRPTASQALRYPYFQI-GHPLGIISKDSGKPQREVQDKTG 309
BLAST of Protein kinase domain-containing protein vs. Ensembl Mouse
Match: Ick (intestinal cell kinase [Source:MGI Symbol;Acc:MGI:1934157]) HSP 1 Score: 401.749 bits (1031), Expect = 1.427e-130 Identity = 192/342 (56.14%), Postives = 244/342 (71.35%), Query Frame = 3
Query: 87 MDKYNFVKQLGDGTYGSVILANVVGTSEKVAIKKMKKKFYSWDECLNLREVKSLRLLKHPNIIRLKEVIRERDCLYLIFEYMNQNLYELIKSRNKPFPEEAIRNIIWQVLEGLTYIHKEGYFHRDLKPENILCNSATQIKLADFGLARSTRSAPPFTDYVATRWCLISLFFTVV*PCFDKPCDFRIHILFNSFLFRYRAPEVLLRSVNYNSPIDIFAVGCIMAELYTFRPLFPGSSEIDMIYKICCVLGTPNKNDWPEGQKLAGTMNFKFPTVTSTNLSVLIPSASRDAIKIMLEMISWNPKNRPTSKDSLQYDYFKTNGQRSGQIT--TKRPLTNVQNTSN 1106
M++Y +KQLGDGTYGSV+L + + E +AIKKMK+KFYSW+EC+NLREVKSL+ L H NI++LKEVIRE D LY IFEYM +NLY+LIK RNK FPE AIRNI++Q+L+GL +IHK G+FHRDLKPEN+LC +K+ADFGLAR RS PP+TDYV+TRW YRAPEVLLRS NY+SPIDI+AVGCIMAE+YT RPLFPG+SEID I+KIC VLGTP K DWPEG +L+ MNF +P NL LIP+AS +AI+++ +++ W+PK RPT+ +L+Y YF+ G G I+ + +P VQ+ +
Sbjct: 1 MNRYTTIKQLGDGTYGSVLLGRSIESGELIAIKKMKRKFYSWEECMNLREVKSLKKLNHANIVKLKEVIRENDHLYFIFEYMKENLYQLIKERNKLFPESAIRNIMYQILQGLAFIHKHGFFHRDLKPENLLCMGPELVKIADFGLAREIRSRPPYTDYVSTRW--------------------------------YRAPEVLLRSTNYSSPIDIWAVGCIMAEVYTLRPLFPGASEIDTIFKICQVLGTPKKTDWPEGYQLSSAMNFLWPQCIPNNLKTLIPNASSEAIQLLRDLLQWDPKKRPTASQALRYPYFQI-GHPLGIISKDSGKPQREVQDKTG 309
BLAST of Protein kinase domain-containing protein vs. Ensembl Mouse
Match: Mak (male germ cell-associated kinase [Source:MGI Symbol;Acc:MGI:96913]) HSP 1 Score: 399.823 bits (1026), Expect = 5.721e-130 Identity = 188/335 (56.12%), Postives = 241/335 (71.94%), Query Frame = 3
Query: 87 MDKYNFVKQLGDGTYGSVILANVVGTSEKVAIKKMKKKFYSWDECLNLREVKSLRLLKHPNIIRLKEVIRERDCLYLIFEYMNQNLYELIKSRNKPFPEEAIRNIIWQVLEGLTYIHKEGYFHRDLKPENILCNSATQIKLADFGLARSTRSAPPFTDYVATRWCLISLFFTVV*PCFDKPCDFRIHILFNSFLFRYRAPEVLLRSVNYNSPIDIFAVGCIMAELYTFRPLFPGSSEIDMIYKICCVLGTPNKNDWPEGQKLAGTMNFKFPTVTSTNLSVLIPSASRDAIKIMLEMISWNPKNRPTSKDSLQYDYFKTN---GQRSGQITTKRPL 1082
M++Y +KQLGDGTYGSV++ + E VAIK+MK+KFYSWDEC+NLREVKSL+ L H N+I+LKEVIRE D LY +FEYM +NLY+L+K RNK FPE IRNI++Q+L+GL +IHK G+FHRD+KPEN+LC +K+ADFGLAR RS PP+TDYV+TRW YRAPEVLLRS Y+SPID++AVG IMAELYTFRPLFPG+SE+D I+KIC VLGTP K+DWPEG +LA +MNF+FP NL LIP+AS +AI++M EM++W+PK RPT+ +L++ YF+ G + + TK+ L
Sbjct: 1 MNRYTTMKQLGDGTYGSVLMGKSNESGELVAIKRMKRKFYSWDECMNLREVKSLKKLNHANVIKLKEVIRENDHLYFVFEYMKENLYQLMKDRNKLFPESVIRNIMYQILQGLAFIHKHGFFHRDMKPENLLCMGPELVKIADFGLARELRSQPPYTDYVSTRW--------------------------------YRAPEVLLRSSVYSSPIDVWAVGSIMAELYTFRPLFPGTSEVDEIFKICQVLGTPKKSDWPEGYQLASSMNFRFPQCIPINLKTLIPNASSEAIQLMTEMLNWDPKKRPTASQALKHPYFQVGQVLGSSAHHLDTKQTL 303
BLAST of Protein kinase domain-containing protein vs. Ensembl Mouse
Match: Mak (male germ cell-associated kinase [Source:MGI Symbol;Acc:MGI:96913]) HSP 1 Score: 399.438 bits (1025), Expect = 6.384e-130 Identity = 188/335 (56.12%), Postives = 241/335 (71.94%), Query Frame = 3
Query: 87 MDKYNFVKQLGDGTYGSVILANVVGTSEKVAIKKMKKKFYSWDECLNLREVKSLRLLKHPNIIRLKEVIRERDCLYLIFEYMNQNLYELIKSRNKPFPEEAIRNIIWQVLEGLTYIHKEGYFHRDLKPENILCNSATQIKLADFGLARSTRSAPPFTDYVATRWCLISLFFTVV*PCFDKPCDFRIHILFNSFLFRYRAPEVLLRSVNYNSPIDIFAVGCIMAELYTFRPLFPGSSEIDMIYKICCVLGTPNKNDWPEGQKLAGTMNFKFPTVTSTNLSVLIPSASRDAIKIMLEMISWNPKNRPTSKDSLQYDYFKTN---GQRSGQITTKRPL 1082
M++Y +KQLGDGTYGSV++ + E VAIK+MK+KFYSWDEC+NLREVKSL+ L H N+I+LKEVIRE D LY +FEYM +NLY+L+K RNK FPE IRNI++Q+L+GL +IHK G+FHRD+KPEN+LC +K+ADFGLAR RS PP+TDYV+TRW YRAPEVLLRS Y+SPID++AVG IMAELYTFRPLFPG+SE+D I+KIC VLGTP K+DWPEG +LA +MNF+FP NL LIP+AS +AI++M EM++W+PK RPT+ +L++ YF+ G + + TK+ L
Sbjct: 1 MNRYTTMKQLGDGTYGSVLMGKSNESGELVAIKRMKRKFYSWDECMNLREVKSLKKLNHANVIKLKEVIRENDHLYFVFEYMKENLYQLMKDRNKLFPESVIRNIMYQILQGLAFIHKHGFFHRDMKPENLLCMGPELVKIADFGLARELRSQPPYTDYVSTRW--------------------------------YRAPEVLLRSSVYSSPIDVWAVGSIMAELYTFRPLFPGTSEVDEIFKICQVLGTPKKSDWPEGYQLASSMNFRFPQCIPINLKTLIPNASSEAIQLMTEMLNWDPKKRPTASQALKHPYFQVGQVLGSSAHHLDTKQTL 303
BLAST of Protein kinase domain-containing protein vs. UniProt/SwissProt
Match: sp|Q9UPZ9|CILK1_HUMAN (Serine/threonine-protein kinase ICK OS=Homo sapiens OX=9606 GN=CILK1 PE=1 SV=1) HSP 1 Score: 402.519 bits (1033), Expect = 4.204e-130 Identity = 186/327 (56.88%), Postives = 237/327 (72.48%), Query Frame = 3
Query: 87 MDKYNFVKQLGDGTYGSVILANVVGTSEKVAIKKMKKKFYSWDECLNLREVKSLRLLKHPNIIRLKEVIRERDCLYLIFEYMNQNLYELIKSRNKPFPEEAIRNIIWQVLEGLTYIHKEGYFHRDLKPENILCNSATQIKLADFGLARSTRSAPPFTDYVATRWCLISLFFTVV*PCFDKPCDFRIHILFNSFLFRYRAPEVLLRSVNYNSPIDIFAVGCIMAELYTFRPLFPGSSEIDMIYKICCVLGTPNKNDWPEGQKLAGTMNFKFPTVTSTNLSVLIPSASRDAIKIMLEMISWNPKNRPTSKDSLQYDYFKTNGQRSGQIT 1067
M++Y ++QLGDGTYGSV+L + + E +AIKKMK+KFYSW+EC+NLREVKSL+ L H N+++LKEVIRE D LY IFEYM +NLY+LIK RNK FPE AIRNI++Q+L+GL +IHK G+FHRDLKPEN+LC +K+ADFGLAR RS PP+TDYV+TRW YRAPEVLLRS NY+SPID++AVGCIMAE+YT RPLFPG+SEID I+KIC VLGTP K DWPEG +L+ MNF++P NL LIP+AS +A++++ +M+ W+PK RPT+ +L+Y YF+ G G T
Sbjct: 1 MNRYTTIRQLGDGTYGSVLLGRSIESGELIAIKKMKRKFYSWEECMNLREVKSLKKLNHANVVKLKEVIRENDHLYFIFEYMKENLYQLIKERNKLFPESAIRNIMYQILQGLAFIHKHGFFHRDLKPENLLCMGPELVKIADFGLAREIRSKPPYTDYVSTRW--------------------------------YRAPEVLLRSTNYSSPIDVWAVGCIMAEVYTLRPLFPGASEIDTIFKICQVLGTPKKTDWPEGYQLSSAMNFRWPQCVPNNLKTLIPNASSEAVQLLRDMLQWDPKKRPTASQALRYPYFQV-GHPLGSTT 294
BLAST of Protein kinase domain-containing protein vs. UniProt/SwissProt
Match: sp|Q9JKV2|CILK1_MOUSE (Serine/threonine-protein kinase ICK OS=Mus musculus OX=10090 GN=Cilk1 PE=1 SV=2) HSP 1 Score: 401.749 bits (1031), Expect = 9.980e-130 Identity = 192/342 (56.14%), Postives = 244/342 (71.35%), Query Frame = 3
Query: 87 MDKYNFVKQLGDGTYGSVILANVVGTSEKVAIKKMKKKFYSWDECLNLREVKSLRLLKHPNIIRLKEVIRERDCLYLIFEYMNQNLYELIKSRNKPFPEEAIRNIIWQVLEGLTYIHKEGYFHRDLKPENILCNSATQIKLADFGLARSTRSAPPFTDYVATRWCLISLFFTVV*PCFDKPCDFRIHILFNSFLFRYRAPEVLLRSVNYNSPIDIFAVGCIMAELYTFRPLFPGSSEIDMIYKICCVLGTPNKNDWPEGQKLAGTMNFKFPTVTSTNLSVLIPSASRDAIKIMLEMISWNPKNRPTSKDSLQYDYFKTNGQRSGQIT--TKRPLTNVQNTSN 1106
M++Y +KQLGDGTYGSV+L + + E +AIKKMK+KFYSW+EC+NLREVKSL+ L H NI++LKEVIRE D LY IFEYM +NLY+LIK RNK FPE AIRNI++Q+L+GL +IHK G+FHRDLKPEN+LC +K+ADFGLAR RS PP+TDYV+TRW YRAPEVLLRS NY+SPIDI+AVGCIMAE+YT RPLFPG+SEID I+KIC VLGTP K DWPEG +L+ MNF +P NL LIP+AS +AI+++ +++ W+PK RPT+ +L+Y YF+ G G I+ + +P VQ+ +
Sbjct: 1 MNRYTTIKQLGDGTYGSVLLGRSIESGELIAIKKMKRKFYSWEECMNLREVKSLKKLNHANIVKLKEVIRENDHLYFIFEYMKENLYQLIKERNKLFPESAIRNIMYQILQGLAFIHKHGFFHRDLKPENLLCMGPELVKIADFGLAREIRSRPPYTDYVSTRW--------------------------------YRAPEVLLRSTNYSSPIDIWAVGCIMAEVYTLRPLFPGASEIDTIFKICQVLGTPKKTDWPEGYQLSSAMNFLWPQCIPNNLKTLIPNASSEAIQLLRDLLQWDPKKRPTASQALRYPYFQI-GHPLGIISKDSGKPQREVQDKTG 309
BLAST of Protein kinase domain-containing protein vs. UniProt/SwissProt
Match: sp|Q62726|CILK1_RAT (Serine/threonine-protein kinase ICK OS=Rattus norvegicus OX=10116 GN=Cilk1 PE=1 SV=1) HSP 1 Score: 400.979 bits (1029), Expect = 1.938e-129 Identity = 191/342 (55.85%), Postives = 244/342 (71.35%), Query Frame = 3
Query: 87 MDKYNFVKQLGDGTYGSVILANVVGTSEKVAIKKMKKKFYSWDECLNLREVKSLRLLKHPNIIRLKEVIRERDCLYLIFEYMNQNLYELIKSRNKPFPEEAIRNIIWQVLEGLTYIHKEGYFHRDLKPENILCNSATQIKLADFGLARSTRSAPPFTDYVATRWCLISLFFTVV*PCFDKPCDFRIHILFNSFLFRYRAPEVLLRSVNYNSPIDIFAVGCIMAELYTFRPLFPGSSEIDMIYKICCVLGTPNKNDWPEGQKLAGTMNFKFPTVTSTNLSVLIPSASRDAIKIMLEMISWNPKNRPTSKDSLQYDYFKTNGQRSGQIT--TKRPLTNVQNTSN 1106
M++Y +KQLGDGTYGSV+L + + E +AIKKMK+KFYSW+EC+NLREVKSL+ L H NI++LKEVIRE D LY IFEYM +NLY+LIK RNK FPE AIRNI++Q+L+GL +IHK G+FHRDLKPEN+LC +K+ADFGLAR RS PP+TDYV+TRW YRAPEVLLRS NY+SPID++AVGCIMAE+YT RPLFPG+SEID I+KIC VLGTP K DWPEG +L+ MNF +P NL LIP+AS +AI+++ +++ W+PK RPT+ +L+Y YF+ G G T + +P +VQ+ +
Sbjct: 1 MNRYTTIKQLGDGTYGSVLLGRSIESGELIAIKKMKRKFYSWEECMNLREVKSLKKLNHANIVKLKEVIRENDHLYFIFEYMKENLYQLIKERNKLFPESAIRNIMYQILQGLAFIHKHGFFHRDLKPENLLCMGPELVKIADFGLAREIRSRPPYTDYVSTRW--------------------------------YRAPEVLLRSTNYSSPIDVWAVGCIMAEVYTLRPLFPGASEIDTIFKICQVLGTPKKTDWPEGYQLSSAMNFIWPQCIPNNLKTLIPNASSEAIQLLRDLLQWDPKKRPTASQALRYPYFQI-GHPLGISTQDSGKPQKDVQDKTG 309
BLAST of Protein kinase domain-containing protein vs. UniProt/SwissProt
Match: sp|Q04859|MAK_MOUSE (Serine/threonine-protein kinase MAK OS=Mus musculus OX=10090 GN=Mak PE=1 SV=2) HSP 1 Score: 399.823 bits (1026), Expect = 4.002e-129 Identity = 188/335 (56.12%), Postives = 241/335 (71.94%), Query Frame = 3
Query: 87 MDKYNFVKQLGDGTYGSVILANVVGTSEKVAIKKMKKKFYSWDECLNLREVKSLRLLKHPNIIRLKEVIRERDCLYLIFEYMNQNLYELIKSRNKPFPEEAIRNIIWQVLEGLTYIHKEGYFHRDLKPENILCNSATQIKLADFGLARSTRSAPPFTDYVATRWCLISLFFTVV*PCFDKPCDFRIHILFNSFLFRYRAPEVLLRSVNYNSPIDIFAVGCIMAELYTFRPLFPGSSEIDMIYKICCVLGTPNKNDWPEGQKLAGTMNFKFPTVTSTNLSVLIPSASRDAIKIMLEMISWNPKNRPTSKDSLQYDYFKTN---GQRSGQITTKRPL 1082
M++Y +KQLGDGTYGSV++ + E VAIK+MK+KFYSWDEC+NLREVKSL+ L H N+I+LKEVIRE D LY +FEYM +NLY+L+K RNK FPE IRNI++Q+L+GL +IHK G+FHRD+KPEN+LC +K+ADFGLAR RS PP+TDYV+TRW YRAPEVLLRS Y+SPID++AVG IMAELYTFRPLFPG+SE+D I+KIC VLGTP K+DWPEG +LA +MNF+FP NL LIP+AS +AI++M EM++W+PK RPT+ +L++ YF+ G + + TK+ L
Sbjct: 1 MNRYTTMKQLGDGTYGSVLMGKSNESGELVAIKRMKRKFYSWDECMNLREVKSLKKLNHANVIKLKEVIRENDHLYFVFEYMKENLYQLMKDRNKLFPESVIRNIMYQILQGLAFIHKHGFFHRDMKPENLLCMGPELVKIADFGLARELRSQPPYTDYVSTRW--------------------------------YRAPEVLLRSSVYSSPIDVWAVGSIMAELYTFRPLFPGTSEVDEIFKICQVLGTPKKSDWPEGYQLASSMNFRFPQCIPINLKTLIPNASSEAIQLMTEMLNWDPKKRPTASQALKHPYFQVGQVLGSSAHHLDTKQTL 303
BLAST of Protein kinase domain-containing protein vs. UniProt/SwissProt
Match: sp|P20793|MAK_RAT (Serine/threonine-protein kinase MAK OS=Rattus norvegicus OX=10116 GN=Mak PE=1 SV=2) HSP 1 Score: 398.282 bits (1022), Expect = 1.734e-128 Identity = 184/317 (58.04%), Postives = 234/317 (73.82%), Query Frame = 3
Query: 87 MDKYNFVKQLGDGTYGSVILANVVGTSEKVAIKKMKKKFYSWDECLNLREVKSLRLLKHPNIIRLKEVIRERDCLYLIFEYMNQNLYELIKSRNKPFPEEAIRNIIWQVLEGLTYIHKEGYFHRDLKPENILCNSATQIKLADFGLARSTRSAPPFTDYVATRWCLISLFFTVV*PCFDKPCDFRIHILFNSFLFRYRAPEVLLRSVNYNSPIDIFAVGCIMAELYTFRPLFPGSSEIDMIYKICCVLGTPNKNDWPEGQKLAGTMNFKFPTVTSTNLSVLIPSASRDAIKIMLEMISWNPKNRPTSKDSLQYDYFK 1037
M++Y ++QLGDGTYGSV++ + E VAIK+MK+KFYSWDEC+NLREVKSL+ L H N+I+LKEVIRE D LY IFEYM +NLY+L+K RNK FPE IRNI++Q+L+GL +IHK G+FHRD+KPEN+LC +K+ADFGLAR RS PP+TDYV+TRW YRAPEVLLRS Y+SPID++AVG IMAELYTFRPLFPG+SE+D I+KIC VLGTP K+DWPEG +LA +MNF+FP NL LIP+AS +AI++M EM++W+PK RPT+ +L++ YF+
Sbjct: 1 MNRYTTMRQLGDGTYGSVLMGKSNESGELVAIKRMKRKFYSWDECMNLREVKSLKKLNHANVIKLKEVIRENDHLYFIFEYMKENLYQLMKDRNKLFPESVIRNIMYQILQGLAFIHKHGFFHRDMKPENLLCMGPELVKIADFGLARELRSQPPYTDYVSTRW--------------------------------YRAPEVLLRSSVYSSPIDVWAVGSIMAELYTFRPLFPGTSEVDEIFKICQVLGTPKKSDWPEGYQLASSMNFRFPQCIPINLKTLIPNASSEAIQLMTEMLNWDPKKRPTASQALKHPYFQ 285
BLAST of Protein kinase domain-containing protein vs. TrEMBL
Match: A0A267G460 (Protein kinase domain-containing protein (Fragment) OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig017647g1 PE=4 SV=1) HSP 1 Score: 439.884 bits (1130), Expect = 9.857e-142 Identity = 263/573 (45.90%), Postives = 330/573 (57.59%), Query Frame = 3
Query: 81 TIMDKYNFVKQLGDGTYGSVILANVVGTSEKVAIKKMKKKFYSWDECLNLREVKSLRLLKHPNIIRLKEVIRERDCLYLIFEYMNQNLYELIKSRNKPFPEEAIRNIIWQVLEGLTYIHKEGYFHRDLKPENILCNSATQIKLADFGLARSTRSAPPFTDYVATRWCLISLFFTVV*PCFDKPCDFRIHILFNSFLFRYRAPEVLLRSVNYNSPIDIFAVGCIMAELYTFRPLFPGSSEIDMIYKICCVLGTPNKNDWPEGQKLAGTMNFKFPTVTSTNLSVLIPSASRDAIKIMLEMISWNPKNRPTSKDSLQYDYFKTNGQRSGQITTKRPLTNVQNTSNLNIDMPTINNI-------MTINQNKPKTDPILD-KSDRRKWAPMEFSDDW---------DFDIGTSKN-----HFSKPVKNEPNPSE-----------IKRQKAFDEF-----DFDMSFIAEMNSKSPQRRKSTKRESXXXXXXLESINNKSKITQKN-----DI------------TSGKENMG-------PFVSGTQRRPSVNKGSASSFYKSNARYHVGMNPRNSGNN 1613
+ M++Y +KQLGDGTYGSV+L + TSEKVAIKKMKKKFY+WDECLNLREVKSLR L HPNI+RLKEV+RE D LYLIFEYM +NLYE++K R K FPEE +RNI+WQ +GL Y+H+ G+FHRDLKPENILCN IKLADFGLAR RS PP+TDYVATRW YRAPE+LLRS +YNSPID+FA+GCIMAELYTFRPLFPGSSEIDMI+KIC VLGTP +DWPEG +LA MNFKFP +T LS LIP+AS D I IML+M++WNPK+RP +KD+L++ YF + QR N SN + + ++ + + + + T P+ KS R +WA D DFD+ S +P+ P + RQ A D + DF SF+ Q++ + ++ + + S I N DI TSGK G P + G RR S K SA S YKS +RY G+NP+++G+N
Sbjct: 18 SSMNRYQTLKQLGDGTYGSVLLGTLTETSEKVAIKKMKKKFYNWDECLNLREVKSLRRLNHPNIVRLKEVVRENDYLYLIFEYMQENLYEVMKKRTKLFPEEVVRNIVWQCTDGLAYMHRMGFFHRDLKPENILCNPDHHIKLADFGLAREIRSKPPYTDYVATRW--------------------------------YRAPEILLRSTSYNSPIDVFAMGCIMAELYTFRPLFPGSSEIDMIFKICSVLGTPRNDDWPEGFQLAAAMNFKFPQCIATQLSSLIPNASTDGIAIMLDMLAWNPKHRPNAKDALKHAYFAASSQRLQPNAASARRQPFNNRSNGQVPIAEVSPLQQQQQQQLVQQRQESVTVPVPGAKSSRNRWAGGGQGPDAKDSFDQLMDDFDLSYSSKPKMARQHQQPLPGLSRPQQPAAKAFPAPPAANRQGATDSWMDADEDFS-SFLGRPAQPPQQQQPARGHQASYLGGGNRAYGGNSGIGGANRRESIDIDDILGSNLLGGPTSGKRMSGKPAGSDLPAMGG--RRDS-GKQSAGSLYKSRSRYLPGINPKSTGSN 554
BLAST of Protein kinase domain-containing protein vs. TrEMBL
Match: G4VTV4 (Serine/threonine kinase OS=Schistosoma mansoni OX=6183 GN=Smp_210970 PE=3 SV=1) HSP 1 Score: 429.098 bits (1102), Expect = 1.359e-140 Identity = 200/339 (59.00%), Postives = 251/339 (74.04%), Query Frame = 3
Query: 87 MDKYNFVKQLGDGTYGSVILANVVGTSEKVAIKKMKKKFYSWDECLNLREVKSLRLLKHPNIIRLKEVIRERDCLYLIFEYMNQNLYELIKSRNKPFPEEAIRNIIWQVLEGLTYIHKEGYFHRDLKPENILCNSATQIKLADFGLARSTRSAPPFTDYVATRWCLISLFFTVV*PCFDKPCDFRIHILFNSFLFRYRAPEVLLRSVNYNSPIDIFAVGCIMAELYTFRPLFPGSSEIDMIYKICCVLGTPNKNDWPEGQKLAGTMNFKFPTVTSTNLSVLIPSASRDAIKIMLEMISWNPKNRPTSKDSLQYDYFKTNGQRSGQITTKRPLTNVQNTS 1103
M++Y +KQLGDGTYGSV+LA V T EKVAIKKMK+KFYSW+ECLNLREVKSL L HPNI++L+E++RE + LYLIF+ + NLYELIK+R + F EE IRNIIWQVL+GL ++HK+G+FHRD+KPEN+LCN +KLADFGLAR RS PP+TDYV+TRW YRAPEVLLRS +YNSP+D+FAVGCIMAELYTFRPLFPGSSEIDM++KIC VLGTP+K+ WPEG +LA MNFKFP + L LIP+A+ + I+++L++ISWNPK+RPT++++L+ YFKT G I++ VQN S
Sbjct: 1 MNRYTLIKQLGDGTYGSVLLATVQETKEKVAIKKMKRKFYSWNECLNLREVKSLSKLSHPNIVKLREIVRENNYLYLIFDALENNLYELIKTRTRLFQEETIRNIIWQVLDGLNFMHKQGFFHRDMKPENLLCNGPETVKLADFGLAREIRSQPPYTDYVSTRW--------------------------------YRAPEVLLRSTSYNSPVDLFAVGCIMAELYTFRPLFPGSSEIDMVFKICSVLGTPSKSGWPEGYQLAAAMNFKFPQCSPVPLHTLIPNANHEGIQLILDLISWNPKHRPTAREALKRPYFKTIRALKGVISSANNGDKVQNIS 307
BLAST of Protein kinase domain-containing protein vs. TrEMBL
Match: A0A183QS61 (Protein kinase domain-containing protein OS=Schistosoma rodhaini OX=6188 PE=3 SV=1) HSP 1 Score: 426.402 bits (1095), Expect = 1.420e-140 Identity = 201/339 (59.29%), Postives = 250/339 (73.75%), Query Frame = 3
Query: 87 MDKYNFVKQLGDGTYGSVILANVVGTSEKVAIKKMKKKFYSWDECLNLREVKSLRLLKHPNIIRLKEVIRERDCLYLIFEYMNQNLYELIKSRNKPFPEEAIRNIIWQVLEGLTYIHKEGYFHRDLKPENILCNSATQIKLADFGLARSTRSAPPFTDYVATRWCLISLFFTVV*PCFDKPCDFRIHILFNSFLFRYRAPEVLLRSVNYNSPIDIFAVGCIMAELYTFRPLFPGSSEIDMIYKICCVLGTPNKNDWPEGQKLAGTMNFKFPTVTSTNLSVLIPSASRDAIKIMLEMISWNPKNRPTSKDSLQYDYFKTNGQRSGQITTKRPLTNVQNTS 1103
M++Y +KQLGDGTYGSV+LA V T EKVAIKKMK+KFYSW+ECLNLREVKSL L HPNI++L+E++RE + LYLIFE + NLYELIK+R + F EE IRNIIWQVL+GL ++HK+G+FHRD+KPEN+LCN +KLADFGLAR RS PP+TDYV+TRW YRAPEVLLRS +YNSP+D+FAVGCIMAELYTFRPLFPGSSEIDM++KIC VLGTP+K+ WPEG +LA MNFKFP + L LIP+A+ + I+++L++ISWNPK+RPT+++SL+ YFKT I++ VQN S
Sbjct: 1 MNRYTLIKQLGDGTYGSVLLATVQETKEKVAIKKMKRKFYSWNECLNLREVKSLSKLSHPNIVKLREIVRENNYLYLIFEALENNLYELIKARTRLFQEETIRNIIWQVLDGLNFMHKQGFFHRDMKPENLLCNGPETVKLADFGLAREIRSQPPYTDYVSTRW--------------------------------YRAPEVLLRSTSYNSPVDLFAVGCIMAELYTFRPLFPGSSEIDMVFKICSVLGTPSKSGWPEGYQLAAAMNFKFPQCSPVPLHTLIPNANHEGIQLILDLISWNPKHRPTARESLKRPYFKTIRALKEVISSANNGDKVQNIS 307
BLAST of Protein kinase domain-containing protein vs. TrEMBL
Match: A0A267ELL4 (Protein kinase domain-containing protein (Fragment) OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig002257g1 PE=4 SV=1) HSP 1 Score: 436.417 bits (1121), Expect = 1.744e-140 Identity = 265/575 (46.09%), Postives = 329/575 (57.22%), Query Frame = 3
Query: 81 TIMDKYNFVKQLGDGTYGSVILANVVGTSEKVAIKKMKKKFYSWDECLNLREVKSLRLLKHPNIIRLKEVIRERDCLYLIFEYMNQNLYELIKSRNKPFPEEAIRNIIWQVLEGLTYIHKEGYFHRDLKPENILCNSATQIKLADFGLARSTRSAPPFTDYVATRWCLISLFFTVV*PCFDKPCDFRIHILFNSFLFRYRAPEVLLRSVNYNSPIDIFAVGCIMAELYTFRPLFPGSSEIDMIYKICCVLGTPNKNDWPEGQKLAGTMNFKFPTVTSTNLSVLIPSASRDAIKIMLEMISWNPKNRPTSKDSLQYDYFKTNGQRSGQITTKRPLTNVQNTSNLNIDMPTINNIMTINQNKPK-------TDPILD-KSDRRKWAPMEFSDDW---------DFDIGTSKN-----HFSKPVKNEPNPSE-----------IKRQKAFDEF-DFDMSFIA----------------------------EMNSKSPQRRKSTKRESXXXXXXLES--INNKSKITQKNDITSGKENMGPFVSGTQRRPSVNKGSASSFYKSNARYHVGMNPRNSGNN 1613
+ M++Y +KQLGDGTYGSV+L + TSEKVAIKKMKKKFY+WDECLNLREVKSLR L HPNI+RLKEV+RE D LYLIFEYM +NLYE++K R K FPEE +RNI+WQ +GL Y+H+ G+FHRDLKPENILCN IKLADFGLAR RS PP+TDYVATRW YRAPE+LLRS +YNSPID+FA+GCIMAELYTFRPLFPGSSEIDMI+KIC VLGTP +DWPEG +LA MNFKFP +T LS LIP+AS D I IML+M++WNPK+RP +KD+L++ YF + QR N SN + + ++ + Q + T P+ KS R +WA D DFD+ S +P+ P + RQ A D + D D F + + +P + +RESIDIDDIL S + + + SGK + RR S K SA S YKS +RY G+NP++ G+N
Sbjct: 18 SSMNRYQTLKQLGDGTYGSVLLGTLTETSEKVAIKKMKKKFYNWDECLNLREVKSLRRLNHPNIVRLKEVVRENDYLYLIFEYMQENLYEVMKKRTKLFPEEVVRNIVWQCTDGLAYMHRMGFFHRDLKPENILCNPDHHIKLADFGLAREIRSKPPYTDYVATRW--------------------------------YRAPEILLRSTSYNSPIDVFAMGCIMAELYTFRPLFPGSSEIDMIFKICSVLGTPRNDDWPEGFQLAAAMNFKFPQCIATQLSSLIPNASTDGIAIMLDMLAWNPKHRPNAKDALKHAYFAASSQRLQPNAASARRQPFNNRSNGQVPIAEVSPLQQQQQQQLVQQRQESVTVPVPGAKSSRNRWAGGGQGPDAKDSFDQLMDDFDLSYSSKPKMARQHQQPLPGLSRPQQPAAKAFPAPPAANRQGATDSWMDADEDFSSFLGRPAQPPQQQQQPARGHQASYLGGGNRAHGGNPGIGGANRRESIDIDDILGSNLLGGPTSGKRVQPQMSGKPAGSDLPAMGGRRDS-GKQSAGSLYKSRSRYLPGINPKSIGSN 559
BLAST of Protein kinase domain-containing protein vs. TrEMBL
Match: A0A3Q0KVA8 (Serine/threonine kinase OS=Schistosoma mansoni OX=6183 PE=3 SV=1) HSP 1 Score: 427.943 bits (1099), Expect = 3.690e-140 Identity = 200/339 (59.00%), Postives = 251/339 (74.04%), Query Frame = 3
Query: 87 MDKYNFVKQLGDGTYGSVILANVVGTSEKVAIKKMKKKFYSWDECLNLREVKSLRLLKHPNIIRLKEVIRERDCLYLIFEYMNQNLYELIKSRNKPFPEEAIRNIIWQVLEGLTYIHKEGYFHRDLKPENILCNSATQIKLADFGLARSTRSAPPFTDYVATRWCLISLFFTVV*PCFDKPCDFRIHILFNSFLFRYRAPEVLLRSVNYNSPIDIFAVGCIMAELYTFRPLFPGSSEIDMIYKICCVLGTPNKNDWPEGQKLAGTMNFKFPTVTSTNLSVLIPSASRDAIKIMLEMISWNPKNRPTSKDSLQYDYFKTNGQRSGQITTKRPLTNVQNTS 1103
M++Y +KQLGDGTYGSV+LA V T EKVAIKKMK+KFYSW+ECLNLREVKSL L HPNI++L+E++RE + LYLIF+ + NLYELIK+R + F EE IRNIIWQVL+GL ++HK+G+FHRD+KPEN+LCN +KLADFGLAR RS PP+TDYV+TRW YRAPEVLLRS +YNSP+D+FAVGCIMAELYTFRPLFPGSSEIDM++KIC VLGTP+K+ WPEG +LA MNFKFP + L LIP+A+ + I+++L++ISWNPK+RPT++++L+ YFKT G I++ VQN S
Sbjct: 1 MNRYTLIKQLGDGTYGSVLLATVQETKEKVAIKKMKRKFYSWNECLNLREVKSLSKLSHPNIVKLREIVRENNYLYLIFDALENNLYELIKTRTRLFQEETIRNIIWQVLDGLNFMHKQGFFHRDMKPENLLCNGPETVKLADFGLAREIRSQPPYTDYVSTRW--------------------------------YRAPEVLLRSTSYNSPVDLFAVGCIMAELYTFRPLFPGSSEIDMVFKICSVLGTPSKSGWPEGYQLAAAMNFKFPQCSPVPLHTLIPNANHEGIQLILDLISWNPKHRPTAREALKRPYFKTIRALKGVISSANNGDKVQNIS 307
BLAST of Protein kinase domain-containing protein vs. Ensembl Cavefish
Match: ICK (serine/threonine-protein kinase ICK-like [Source:NCBI gene;Acc:103040253]) HSP 1 Score: 392.889 bits (1008), Expect = 1.039e-127 Identity = 184/324 (56.79%), Postives = 237/324 (73.15%), Query Frame = 3
Query: 87 MDKYNFVKQLGDGTYGSVILANVVGTSEKVAIKKMKKKFYSWDECLNLREVKSLRLLKHPNIIRLKEVIRERDCLYLIFEYMNQNLYELIKSRNKPFPEEAIRNIIWQVLEGLTYIHKEGYFHRDLKPENILCNSATQIKLADFGLARSTRSAPPFTDYVATRWCLISLFFTVV*PCFDKPCDFRIHILFNSFLFRYRAPEVLLRSVNYNSPIDIFAVGCIMAELYTFRPLFPGSSEIDMIYKICCVLGTPNKNDWPEGQKLAGTMNFKFPTVTSTNLSVLIPSASRDAIKIMLEMISWNPKNRPTSKDSLQYDYFKTNGQRSG 1058
M++Y+ ++QLGDGTYGSVIL+ + + E VAIKKMK+KFYSW+EC+NLREVKSL+ L H N+I+LKEVIRE D LY +FEYM +NLY+L+K R + FPE A+RNI++Q+L+GL +IHK G+FHRDLKPEN+LC +K+ADFGLAR RS PP+TDYV+TRW YRAPEVLLRS +Y+SPID +AVGCIMAELY+ RPLFPGSSE+D I+KIC VLGTP KNDW EG LA TM+F++P T+L LIP+AS +AI++M +++ W+PK RP + +L+Y YF+ GQ G
Sbjct: 1 MNRYSALRQLGDGTYGSVILSRCLESGELVAIKKMKRKFYSWEECMNLREVKSLKKLNHANVIKLKEVIREHDHLYFVFEYMKENLYQLMKDRTRLFPESAVRNIMFQILQGLAFIHKHGFFHRDLKPENLLCMGPELVKIADFGLAREIRSRPPYTDYVSTRW--------------------------------YRAPEVLLRSTSYSSPIDQWAVGCIMAELYSLRPLFPGSSEVDTIFKICQVLGTPKKNDWAEGYHLAATMSFRWPQCVPTSLRTLIPNASTEAIQLMRDLLQWDPKKRPAASQALRYPYFQV-GQVCG 291
BLAST of Protein kinase domain-containing protein vs. Ensembl Cavefish
Match: ICK (serine/threonine-protein kinase ICK-like [Source:NCBI gene;Acc:103040253]) HSP 1 Score: 392.889 bits (1008), Expect = 2.572e-127 Identity = 184/324 (56.79%), Postives = 237/324 (73.15%), Query Frame = 3
Query: 87 MDKYNFVKQLGDGTYGSVILANVVGTSEKVAIKKMKKKFYSWDECLNLREVKSLRLLKHPNIIRLKEVIRERDCLYLIFEYMNQNLYELIKSRNKPFPEEAIRNIIWQVLEGLTYIHKEGYFHRDLKPENILCNSATQIKLADFGLARSTRSAPPFTDYVATRWCLISLFFTVV*PCFDKPCDFRIHILFNSFLFRYRAPEVLLRSVNYNSPIDIFAVGCIMAELYTFRPLFPGSSEIDMIYKICCVLGTPNKNDWPEGQKLAGTMNFKFPTVTSTNLSVLIPSASRDAIKIMLEMISWNPKNRPTSKDSLQYDYFKTNGQRSG 1058
M++Y+ ++QLGDGTYGSVIL+ + + E VAIKKMK+KFYSW+EC+NLREVKSL+ L H N+I+LKEVIRE D LY +FEYM +NLY+L+K R + FPE A+RNI++Q+L+GL +IHK G+FHRDLKPEN+LC +K+ADFGLAR RS PP+TDYV+TRW YRAPEVLLRS +Y+SPID +AVGCIMAELY+ RPLFPGSSE+D I+KIC VLGTP KNDW EG LA TM+F++P T+L LIP+AS +AI++M +++ W+PK RP + +L+Y YF+ GQ G
Sbjct: 1 MNRYSALRQLGDGTYGSVILSRCLESGELVAIKKMKRKFYSWEECMNLREVKSLKKLNHANVIKLKEVIREHDHLYFVFEYMKENLYQLMKDRTRLFPESAVRNIMFQILQGLAFIHKHGFFHRDLKPENLLCMGPELVKIADFGLAREIRSRPPYTDYVSTRW--------------------------------YRAPEVLLRSTSYSSPIDQWAVGCIMAELYSLRPLFPGSSEVDTIFKICQVLGTPKKNDWAEGYHLAATMSFRWPQCVPTSLRTLIPNASTEAIQLMRDLLQWDPKKRPAASQALRYPYFQV-GQVCG 291
BLAST of Protein kinase domain-containing protein vs. Ensembl Cavefish
Match: mak (male germ cell associated kinase [Source:NCBI gene;Acc:103025131]) HSP 1 Score: 355.91 bits (912), Expect = 3.980e-113 Identity = 169/313 (53.99%), Postives = 214/313 (68.37%), Query Frame = 3
Query: 189 MKKKFYSWDECLNLREVKSLRLLKHPNIIRLKEVIRERDCLYLIFEYMNQNLYELIKSRNKPFPEEAIRNIIWQVLEGLTYIHKEGYFHRDLKPENILCNSATQIKLADFGLARSTRSAPPFTDYVATRWCLISLFFTVV*PCFDKPCDFRIHILFNSFLFRYRAPEVLLRSVNYNSPIDIFAVGCIMAELYTFRPLFPGSSEIDMIYKICCVLGTPNKNDWPEGQKLAGTMNFKFPTVTSTNLSVLIPSASRDAIKIMLEMISWNPKNRPTSKDSLQYDYFKTNGQRSGQITTKRPLTNVQNTSNLNIDMPT 1127
MK+KFYSW+EC+NLREVKSL+ L H N+++LKEVIRE D LY +FEYM +NLY+L+K RNK FPE AIRNI +Q+L+GL++IHK G+FHRD+KPEN+LC +K+ADFGLAR TRS PP+TDYV+TRW YRAPEVLLRS Y+SPID++AVGCIMAELYT RPLFPG+SE+D I+KIC VLGT K DWPEG +LA MNF+FP T L LIP+AS +A+ +M +++ W+PK RPT+ +L+Y YF+ GQ+ R T + PT
Sbjct: 1 MKRKFYSWEECMNLREVKSLKKLNHANVVKLKEVIRENDHLYFVFEYMKENLYQLMKDRNKLFPESAIRNITFQILQGLSFIHKHGFFHRDMKPENLLCMGPELVKIADFGLARETRSRPPYTDYVSTRW--------------------------------YRAPEVLLRSSMYSSPIDMWAVGCIMAELYTLRPLFPGNSEVDEIFKICQVLGTVKKTDWPEGYQLAAAMNFRFPQCVPTPLKTLIPNASNEALTLMKDLLQWDPKKRPTAVQALRYPYFQV-----GQVLGPRTQTPDLRKPQMKPAQPT 276
BLAST of Protein kinase domain-containing protein vs. Ensembl Cavefish
Match: mak (male germ cell associated kinase [Source:NCBI gene;Acc:103025131]) HSP 1 Score: 344.739 bits (883), Expect = 7.069e-109 Identity = 167/314 (53.18%), Postives = 211/314 (67.20%), Query Frame = 3
Query: 189 MKKKFYSWDECLNLREVKSLRLLKHPNIIRLKEVIRERDCLYLIFEYMNQNLYELIKSR-NKPFPEEAIRNIIWQVLEGLTYIHKEGYFHRDLKPENILCNSATQIKLADFGLARSTRSAPPFTDYVATRWCLISLFFTVV*PCFDKPCDFRIHILFNSFLFRYRAPEVLLRSVNYNSPIDIFAVGCIMAELYTFRPLFPGSSEIDMIYKICCVLGTPNKNDWPEGQKLAGTMNFKFPTVTSTNLSVLIPSASRDAIKIMLEMISWNPKNRPTSKDSLQYDYFKTNGQRSGQITTKRPLTNVQNTSNLNIDMPT 1127
MK+KFYSW+EC+NLREVKSL+ L H N+++LKEVIRE D LY +FEYM +NLY+L+K R NK F E IRNI++QVL GL ++HK G+FHRD+KPEN+LC +K+ADFGLAR TRS PP+TDYV+TRW YRAPEVLLRS Y+SPID++AVGCIMAELYT RPLFPG+SE+D I+KIC VLGT K DWPEG +LA MNF+FP T L LIP+AS +A+ +M +++ W+PK RPT+ +L+Y YF+ GQ+ R T + PT
Sbjct: 1 MKRKFYSWEECMNLREVKSLKKLNHANVVKLKEVIRENDHLYFVFEYMKENLYQLMKDRENKMFTENEIRNIMFQVLSGLAFVHKHGFFHRDMKPENLLCMGPELVKIADFGLARETRSRPPYTDYVSTRW--------------------------------YRAPEVLLRSSMYSSPIDMWAVGCIMAELYTLRPLFPGNSEVDEIFKICQVLGTVKKTDWPEGYQLAAAMNFRFPQCVPTPLKTLIPNASNEALTLMKDLLQWDPKKRPTAVQALRYPYFQV-----GQVLGPRTQTPDLRKPQMKPAQPT 277
BLAST of Protein kinase domain-containing protein vs. Ensembl Cavefish
Match: mak (male germ cell associated kinase [Source:NCBI gene;Acc:103025131]) HSP 1 Score: 343.969 bits (881), Expect = 7.072e-109 Identity = 167/314 (53.18%), Postives = 211/314 (67.20%), Query Frame = 3
Query: 189 MKKKFYSWDECLNLREVKSLRLLKHPNIIRLKEVIRERDCLYLIFEYMNQNLYELIKSR-NKPFPEEAIRNIIWQVLEGLTYIHKEGYFHRDLKPENILCNSATQIKLADFGLARSTRSAPPFTDYVATRWCLISLFFTVV*PCFDKPCDFRIHILFNSFLFRYRAPEVLLRSVNYNSPIDIFAVGCIMAELYTFRPLFPGSSEIDMIYKICCVLGTPNKNDWPEGQKLAGTMNFKFPTVTSTNLSVLIPSASRDAIKIMLEMISWNPKNRPTSKDSLQYDYFKTNGQRSGQITTKRPLTNVQNTSNLNIDMPT 1127
MK+KFYSW+EC+NLREVKSL+ L H N+++LKEVIRE D LY +FEYM +NLY+L+K R NK F E IRNI++QVL GL ++HK G+FHRD+KPEN+LC +K+ADFGLAR TRS PP+TDYV+TRW YRAPEVLLRS Y+SPID++AVGCIMAELYT RPLFPG+SE+D I+KIC VLGT K DWPEG +LA MNF+FP T L LIP+AS +A+ +M +++ W+PK RPT+ +L+Y YF+ GQ+ R T + PT
Sbjct: 1 MKRKFYSWEECMNLREVKSLKKLNHANVVKLKEVIRENDHLYFVFEYMKENLYQLMKDRENKMFTENEIRNIMFQVLSGLAFVHKHGFFHRDMKPENLLCMGPELVKIADFGLARETRSRPPYTDYVSTRW--------------------------------YRAPEVLLRSSMYSSPIDMWAVGCIMAELYTLRPLFPGNSEVDEIFKICQVLGTVKKTDWPEGYQLAAAMNFRFPQCVPTPLKTLIPNASNEALTLMKDLLQWDPKKRPTAVQALRYPYFQV-----GQVLGPRTQTPDLRKPQMKPAQPT 277
BLAST of Protein kinase domain-containing protein vs. Ensembl Sea Lamprey
Match: mak (male germ cell-associated kinase [Source:ZFIN;Acc:ZDB-GENE-030131-7279]) HSP 1 Score: 406.757 bits (1044), Expect = 2.751e-133 Identity = 195/347 (56.20%), Postives = 241/347 (69.45%), Query Frame = 3
Query: 87 MDKYNFVKQLGDGTYGSVILANVVGTSEKVAIKKMKKKFYSWDECLNLREVKSLRLLKHPNIIRLKEVIRERDCLYLIFEYMNQNLYELIKSRNKPFPEEAIRNIIWQVLEGLTYIHKEGYFHRDLKPENILCNSATQIKLADFGLARSTRSAPPFTDYVATRWCLISLFFTVV*PCFDKPCDFRIHILFNSFLFRYRAPEVLLRSVNYNSPIDIFAVGCIMAELYTFRPLFPGSSEIDMIYKICCVLGTPNKNDWPEGQKLAGTMNFKFPTVTSTNLSVLIPSASRDAIKIMLEMISWNPKNRPTSKDSLQYDYFKTNGQRSGQITTKRPLTNVQNTSNLNIDMPT 1127
M++Y +KQLGDGTYGSV++ T E VAIKKMK+KFYSWDEC+NLREVKSL+ L H N+I+LKEVIRE DCLY +FEYM +NLY+L+K RNK FPE IRNI++Q+L+GL +IHK G+FHRD+KPEN+LC +K+ADFGLAR RS PP+TDYV+TRW YR PEVLLRS +Y+SPIDI+A+GCIMAELYT RPLFPGSSE+D I+KIC VLGTP KNDWPEG +LA MNF++P TNL LIP+AS +AI +M +M+ W PK RP + SL+Y YF+ GQ G +PL + S + P
Sbjct: 1 MNRYTTIKQLGDGTYGSVLMGRSNETGELVAIKKMKRKFYSWDECMNLREVKSLKKLNHANVIKLKEVIRENDCLYFVFEYMKENLYQLMKDRNKLFPESMIRNIMYQILQGLAFIHKHGFFHRDMKPENLLCMGPELVKIADFGLAREIRSRPPYTDYVSTRW--------------------------------YRGPEVLLRSTSYSSPIDIWALGCIMAELYTLRPLFPGSSEVDQIFKICQVLGTPKKNDWPEGHQLAAAMNFRWPQCVPTNLKTLIPNASNEAIHLMRDMLHWEPKKRPNAVQSLRYPYFQV-GQALG---PPQPLQHQAQPSEQPLKPPA 311
BLAST of Protein kinase domain-containing protein vs. Ensembl Sea Lamprey
Match: cdk2 (cyclin-dependent kinase 2 [Source:ZFIN;Acc:ZDB-GENE-040426-2741]) HSP 1 Score: 183.341 bits (464), Expect = 1.025e-52 Identity = 108/330 (32.73%), Postives = 177/330 (53.64%), Query Frame = 3
Query: 87 MDKYNFVKQLGDGTYGSVILANVVGTSEKVAIKKMKKKFYSWD-ECLNLREVKSLRLLKHPNIIRLKEVIRERDCLYLIFEYMNQNLYELIKSRNKP-FPEEAIRNIIWQVLEGLTYIHKEGYFHRDLKPENILCNSATQIKLADFGLARSTRSAP--PFTDYVATRWCLISLFFTVV*PCFDKPCDFRIHILFNSFLFRYRAPEVLLRSVNYNSPIDIFAVGCIMAELYTFRPLFPGSSEIDMIYKICCVLGTPNKNDWPEGQKLAGTMNFKFPTVTSTNLSVLIPSASRDAIKIMLEMISWNPKNRPTSKDSLQYDYFKTNGQRSGQI 1064
MD + V+++G+GTYG V A T E VA+KK++ + +RE+ LR L HPNI+RL +I LYL+FE ++Q+L + + + P +++ ++Q+L+G+ + H HRDLKP+N+L N+ IKLADFGLAR+ P +T V T W YRAPE+LL +Y++ +D++++GCI AE+ T R LFPG SEID +++I LGTP++ WP +L + FP + L+ ++P+ + + ++ M+ ++P R T+ +L + +F+ Q Q+
Sbjct: 1 MDNFQKVEKIGEGTYGVVYKARNKLTGEAVALKKIRLDTETEGVPSTAIREISLLRELNHPNIVRLLTIIHSEKKLYLVFELLDQDLKKFMDNATPSGIPLPLVKSYLYQLLQGIAFCHSHRILHRDLKPQNLLINAEGAIKLADFGLARAF-GVPQRTYTHEVVTLW--------------------------------YRAPEILLGCKHYSTSVDVWSIGCIFAEMLTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVSQLPDYKS-TFPRWANQELTKVVPTLNFEGRDLLALMLQYDPNQRVTANMALSHCFFQNVKQIVPQL 296
BLAST of Protein kinase domain-containing protein vs. Ensembl Sea Lamprey
Match: cdk2 (cyclin-dependent kinase 2 [Source:ZFIN;Acc:ZDB-GENE-040426-2741]) HSP 1 Score: 178.333 bits (451), Expect = 5.785e-51 Identity = 107/324 (33.02%), Postives = 176/324 (54.32%), Query Frame = 3
Query: 87 MDKYNFVKQLGDGTYGSVILANVVGTSEKVAIKKMKKKFYSWD-ECLNLREVKSLRLLKHPNIIRLKEVIRERDCLYLIFEYMNQNLYELIKSRNKP---FPEEAIRNIIWQVLEGLTYIHKEGYFHRDLKPENILCNSATQIKLADFGLARSTRSAP--PFTDYVATRWCLISLFFTVV*PCFDKPCDFRIHILFNSFLFRYRAPEVLLRSVNYNSPIDIFAVGCIMAELYTFRPLFPGSSEIDMIYKICCVLGTPNKNDWPEGQKLAGTMNFK--FPTVTSTNLSVLIPSASRDAIKIMLEMISWNPKNRPTSKDSLQYDYF 1034
MD + V+++G+GTYG V A T + VA+KK++ + +RE+ LR L HPNI+RL +VI LYL+FE+++Q+L + + N P +++ + Q+L+G+ + H + HRDLKP+N+L N+ IKLADFGLAR+ P +T V T W YRAPE+LL Y++ +D++++GCI AE+ T R LFPG SEID +++I LGTP++ W Q + ++K FP + +L+ ++P ++++M+ ++P R ++K +L + +F
Sbjct: 1 MDLFQKVEKIGEGTYGVVYKARHKMTGDTVALKKIRLDTETEGVPSTAIREIALLRELNHPNIVRLLDVIHSETKLYLVFEFLDQDLKKYMD--NAPPLGISLPLVKSYMHQLLQGIAFCHAQRTLHRDLKPQNLLINADGAIKLADFGLARAF-GVPLRTYTHEVVTLW--------------------------------YRAPEILLGCKYYSTAVDVWSLGCIFAEMLTRRALFPGDSEIDQLFRIFRTLGTPDETVW---QGITQLPDYKPSFPRWCAQDLTKVVPLLDAAGHDLLMQMLQYDPTRRVSAKAALNHHFF 286
BLAST of Protein kinase domain-containing protein vs. Ensembl Sea Lamprey
Match: mapk12a (mitogen-activated protein kinase 12a [Source:NCBI gene;Acc:30681]) HSP 1 Score: 174.866 bits (442), Expect = 7.577e-49 Identity = 108/328 (32.93%), Postives = 172/328 (52.44%), Query Frame = 3
Query: 93 KYNFVKQLGDGTYGSVILANVVGTSEKVAIKKMKKKFYSWDECLNLREVKSLRLLKH---PNIIRLKEVIRERDCL------YLIFEYMNQNLYELIKSRNKPFPEEAIRNIIWQVLEGLTYIHKEGYFHRDLKPENILCNSATQIKLADFGLARSTRSAPPFTDYVATRWCLISLFFTVV*PCFDKPCDFRIHILFNSFLFRYRAPEVLLRSVNYNSPIDIFAVGCIMAELYTFRPLFPGSSEIDMIYKICCVLGTP-----NKNDWPEGQKLAGTMNFKFPTVTSTNLSVLIPSASRDAIKIMLEMISWNPKNRPTSKDSLQYDYF 1034
+Y+ + +G G YG+V + + T KVA+KK+ + F S R + LRLLKH N+I L +V D L YL+ +M +L +++K + ++ ++ +I+Q+L+GL YIH G HRDLKP N+ N ++K+ DFGLAR T YV TRW YRAPEV+L ++Y +DI++VGCIMAE+ T +PLFPG+ +D + I + GTP ++ D E K T+ P + +S + P+A+ AI ++ +M++ +P+ RPT+ ++LQ+ +F
Sbjct: 26 RYSQLFAVGSGAYGTVCSSMDLVTGSKVAVKKLYRPFQS--RVFAKRAYRELRLLKHMKHENVIGLVDVFTPNDTLDQFQDFYLVMPFMGTDLSKIMKHGKQS--DDKVQYLIYQILKGLKYIHSSGIIHRDLKPGNLAVNEDCELKILDFGLARHADQE--MTGYVVTRW--------------------------------YRAPEVILNWMHYTQTVDIWSVGCIMAEMITGKPLFPGNDHMDQLMLILKLTGTPPQYLVDRMDENEAAKYIKTL----PKMEKRRISTVFPNANPIAIDLLEKMLALDPEQRPTASEALQHPFF 311
BLAST of Protein kinase domain-containing protein vs. Ensembl Sea Lamprey
Match: cdk1 (cyclin-dependent kinase 1 [Source:ZFIN;Acc:ZDB-GENE-010320-1]) HSP 1 Score: 168.703 bits (426), Expect = 1.444e-47 Identity = 104/314 (33.12%), Postives = 166/314 (52.87%), Query Frame = 3
Query: 123 GTYGSVILANVVGTSEKVAIKKMKKKFYSWD-ECLNLREVKSLRLLKHPNIIRLKEVIRERDCLYLIFEYMNQNLYELIKSRNKPF----PEEAIRNIIWQVLEGLTYIHKEGYFHRDLKPENILCNSATQIKLADFGLARSTRSAPP--FTDYVATRWCLISLFFTVV*PCFDKPCDFRIHILFNSFLFRYRAPEVLLRSVNYNSPIDIFAVGCIMAELYTFRPLFPGSSEIDMIYKICCVLGTPNKNDWPEGQKLAGTMNFK--FPTVTSTNLSVLIPSASRDAIKIMLEMISWNPKNRPTSKDSLQYDYFK 1037
G+YG V GT + VA+KK++ + +RE+ LR L+HPNI+RL++V+ + LYLIFEY+ +L + + P ++ + Q+L+ + + H HRDLKP+N+L + IKLADFGLAR+ P +T V T W YRAPEVLL + Y++P+D+++VG I+AE+ RPLF G SEID +++I +LGTP WP+ L ++K FP + L +P ++D I ++ +M++++P R ++K +L + YF+
Sbjct: 1 GSYGVVYKGRNKGTGDLVALKKIRLEHEEEGVPATAIREIALLRELRHPNIVRLQDVLLQSARLYLIFEYLPMDLKRYLDAIPAGHCMEPPLIQGQSYLHQILQAVVFCHSRRVLHRDLKPQNLLIDRHGHIKLADFGLARAF-GVPVRVYTHEVVTLW--------------------------------YRAPEVLLGTPRYSTPVDMWSVGTILAEMVNKRPLFHGDSEIDQLFRIFRILGTPTTEVWPDVVTLP---DYKPSFPKWVPSGLVAHVPGLNQDGIDLLEKMLTYDPARRISAKRALTHPYFQ 278
BLAST of Protein kinase domain-containing protein vs. Ensembl Yeast
Match: IME2 (Serine/threonine protein kinase involved in activation of meiosis; associates with Ime1p and mediates its stability, activates Ndt80p; IME2 expression is positively regulated by Ime1p; human CDK2 can complement ime2 null mutant [Source:SGD;Acc:S000003642]) HSP 1 Score: 176.407 bits (446), Expect = 1.922e-47 Identity = 147/500 (29.40%), Postives = 230/500 (46.00%), Query Frame = 3
Query: 81 TIMDKYNFVKQLGDGTYGSVILA-------NVVG-----------------------TSEKVAIKKMKKKFYSWDECLNLREVK-SLRLLKHPNIIRLKEVI--RERDCLYLIFEYMNQNLYELIKSRNK-PFPEEAIRNIIWQVLEGLTYIHKEGYFHRDLKPENILCNSATQ-----------------IKLADFGLARSTRSAPPFTDYVATRWCLISLFFTVV*PCFDKPCDFRIHILFNSFLFRYRAPEVLLRSVNYNSPIDIFAVGCIMAELYTFRPLFPGSSEIDMIYKICCVLGTP-------NKND---------WPEGQKLAGTMNFKFPTVTS-TNLSVLIPSASRDAIKIMLEMISWNPKNRPTSKDSLQYDYFKTNGQRSGQITTKRPLTNVQNTSNLNIDMPTINNIMTINQNKPKTDPILDKSDRRKWAPMEFSDDWDFDIGTSKNH-FSKPVKNEPNPSEIKRQKAFDEFDFDMSFIAEMNSKS 1373
T+ D+Y +++LG G++G V LA N++G T VAIK M K ++ + +RE+K L + + ++I++ EV E L+++ E M QNLY+++K R + F ++++I+ Q+L GL +IH+ +FHRDLKPENIL +TQ IKLADFGLAR + P+T YV+TRW YR+PE+LLRS Y+ P+DI+A GC+ E+ FR LFPG++EID I+KI VLGTP N N W + L +N K P V + +L S D +++ + + W+P R T+++ + +F+ + Q+ + +TN + + IN + T T PI S + A E S+D D +H P N+ + ++ F E D D I ++ + S
Sbjct: 33 TLSDRYQLIEKLGAGSFGCVTLAKAQFPLSNILGKQHDIRGTLMDQPKNGHQNYITKTQGVVAIKTMMTKLHTLQDYTRVREIKFILAIPANDHLIQIFEVFIDSENYQLHIVMECMEQNLYQMMKHRRRRVFSIPSLKSILSQILAGLKHIHEHNFFHRDLKPENILITPSTQYFEKEYMNQIGYQDNYVIKLADFGLARHVENKNPYTAYVSTRW--------------------------------YRSPEILLRSGYYSKPLDIWAFGCVAVEVTVFRALFPGANEIDQIWKILEVLGTPIKRSDFVNTNHITAPPPGGFWDDASNLVHKLNLKLPYVEGSSLDHLLSSSQLSDLSEVVKKCLRWDPNERATAQELCEMPFFE--NTVASQVDARGNVTNTEQA----LIFAGINPVAT------NTKPIYFNSSTKLPAETE-SNDIDISNNDHDSHAMCSPTLNQEKLTLVEFLNEFVEEDNDDHSIPDVGTDS 487
BLAST of Protein kinase domain-containing protein vs. Ensembl Yeast
Match: CDC28 (Cyclin-dependent kinase (CDK) catalytic subunit; master regulator of mitotic and meiotic cell cycles; alternately associates with G1, S, G2/M phase cyclins, which provide substrate specificity; regulates metabolism, basal transcription, chromosome dynamics, growth and morphogenesis; transcript induction in osmostress involves antisense RNA; human homologs CDK1, CDK2, CDK3 can complement yeast conditional cdc28 mutants; human CDK1, CDK2 can complement yeast cdc28 null mutant [Source:SGD;Acc:S000000364]) HSP 1 Score: 163.31 bits (412), Expect = 1.134e-45 Identity = 105/329 (31.91%), Postives = 180/329 (54.71%), Query Frame = 3
Query: 96 YNFVKQLGDGTYGSVILANVV--GTSEKV-AIKKMKKKFYSWDECL---NLREVKSLRLLKHPNIIRLKEVIR-ERDCLYLIFEYMNQNLYELIKS--RNKPFPEEAIRNIIWQVLEGLTYIHKEGYFHRDLKPENILCNSATQIKLADFGLARSTRSAP--PFTDYVATRWCLISLFFTVV*PCFDKPCDFRIHILFNSFLFRYRAPEVLLRSVNYNSPIDIFAVGCIMAELYTFRPLFPGSSEIDMIYKICCVLGTPNKNDWPEGQKLAGTMNFK--FPTVTSTNLSVLIPSASRDAIKIMLEMISWNPKNRPTSKDSLQYDYFKTN 1043
Y ++++G+GTYG V A + G ++V A+KK++ + S DE + +RE+ L+ LK NI+RL +++ + LYL+FE+++ +L ++ +++P + ++ + Q+ +G+ Y H HRDLKP+N+L N +KL DFGLAR+ P +T + T W YRAPEVLL Y++ +D +++GCI AE+ +P+F G SEID I+KI VLGTPN+ WP+ L +FK FP +LS ++PS I ++ ++++++P NR +++ + + YF+ +
Sbjct: 8 YKRLEKVGEGTYGVVYKALDLRPGQGQRVVALKKIRLE--SEDEGVPSTAIREISLLKELKDDNIVRLYDIVHSDAHKLYLVFEFLDLDLKRYMEGIPKDQPLGADIVKKFMMQLCKGIAYCHSHRILHRDLKPQNLLINKDGNLKLGDFGLARAF-GVPLRAYTHEIVTLW--------------------------------YRAPEVLLGGKQYSTGVDTWSIGCIFAEMCNRKPIFSGDSEIDQIFKIFRVLGTPNEAIWPDIVYLP---DFKPSFPQWRRKDLSQVVPSLDPRGIDLLDKLLAYDPINRISARRAAIHPYFQES 298
BLAST of Protein kinase domain-containing protein vs. Ensembl Yeast
Match: KIN28 (Serine/threonine protein kinase, subunit of transcription factor TFIIH; involved in transcription initiation at RNA polymerase II promoters; phosphorylates Ser5 residue of the PolII C-terminal domain (CTD) at gene promoters; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000002266]) HSP 1 Score: 161.77 bits (408), Expect = 4.743e-45 Identity = 107/319 (33.54%), Postives = 158/319 (49.53%), Query Frame = 3
Query: 93 KYNFVKQLGDGTYGSVILANVVGTSEKVAIKKMK-KKFYSWDECLNLREVKSLRLLKHPNIIRLKEVIRERDCLYLIFEYMNQNLYELIKSRNKPFPEEAIRNIIWQVLEGLTYIHKEGYFHRDLKPENILCNSATQIKLADFGLARSTRSAPP--FTDYVATRWCLISLFFTVV*PCFDKPCDFRIHILFNSFLFRYRAPEVLLRSVNYNSPIDIFAVGCIMAELYTFRPLFPGSSEIDMIYKICCVLGTPNKNDWPEGQKLAGTMNFK-FPTVTSTNLSVLIPSASRDAIKIMLEMISWNPKNRPTSKDSLQYDYFK 1037
+Y K++G+GTY V L T K+AIK++K +F + +REVK L+ ++HPN+I L ++ D L L+ E++ +L +IK ++ F I+ + L G+ + H+ HRDLKP N+L + QIK+ADFGLAR+ AP T V TRW YRAPE+L + +Y S IDI++VG I AEL P PG +++D + LGTP DWPE + +P + L +AS A+ M M++ NP+ R T+ L+ DYFK
Sbjct: 6 EYTKEKKVGEGTYAVVYLGCQHSTGRKIAIKEIKTSEFKDGLDMSAIREVKYLQEMQHPNVIELIDIFMAYDNLNLVLEFLPTDLEVVIKDKSILFTPADIKAWMLMTLRGVYHCHRNFILHRDLKPNNLLFSPDGQIKVADFGLARAI-PAPHEILTSNVVTRW--------------------------------YRAPELLFGAKHYTSAIDIWSVGVIFAELMLRIPYLPGQNDVDQMEVTFRALGTPTDRDWPEVSSFMTYNKLQIYPPPSRDELRKRFIAASEYALDFMCGMLTMNPQKRWTAVQCLESDYFK 291
BLAST of Protein kinase domain-containing protein vs. Ensembl Yeast
Match: PHO85 (Cyclin-dependent kinase; has ten cyclin partners; involved in regulating the cellular response to nutrient levels and environmental conditions and progression through the cell cycle; human lissencephaly-associated homolog CDK5 functionally complements null mutation [Source:SGD;Acc:S000005952]) HSP 1 Score: 155.992 bits (393), Expect = 5.241e-43 Identity = 103/325 (31.69%), Postives = 166/325 (51.08%), Query Frame = 3
Query: 93 KYNFVKQLGDGTYGSVILANVVGTSEKVAIKKMKKKFYSWDECLNLREVKSLRLLKHPNIIRLKEVIRERDCLYLIFEYMNQNLYELIKSR---NKPFPEEA--IRNIIWQVLEGLTYIHKEGYFHRDLKPENILCNSATQIKLADFGLARSTR-SAPPFTDYVATRWCLISLFFTVV*PCFDKPCDFRIHILFNSFLFRYRAPEVLLRSVNYNSPIDIFAVGCIMAELYTFRPLFPGSSEIDMIYKICCVLGTPNKNDWPEGQKLAGTMNFKFPTVTSTNL-SVLIPSASR----DAIKIMLEMISWNPKNRPTSKDSLQYDYF 1034
++ +++LG+GTY +V T VA+K++K +RE+ ++ LKH NI+RL +VI + L L+FE+M+ +L + + SR N P E ++ WQ+L+GL + H+ HRDLKP+N+L N Q+KL DFGLAR+ F+ V T W YRAP+VL+ S Y++ IDI++ GCI+AE+ T +PLFPG+++ + + I ++GTPN++ WP KL N +L VL P + + + ++ NP R ++K +L + +F
Sbjct: 6 QFKQLEKLGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPSTAIREISLMKELKHENIVRLYDVIHTENKLTLVFEFMDNDLKKYMDSRTVGNTPRGLELNLVKYFQWQLLQGLAFCHENKILHRDLKPQNLLINKRGQLKLGDFGLARAFGIPVNTFSSEVVTLW--------------------------------YRAPDVLMGSRTYSTSIDIWSCGCILAEMITGKPLFPGTNDEEQLKLIFDIMGTPNESLWPSVTKLP-KYNPNIQQRPPRDLRQVLQPHTKEPLDGNLMDFLHGLLQLNPDMRLSAKQALHHPWF 297
BLAST of Protein kinase domain-containing protein vs. Ensembl Yeast
Match: HOG1 (Mitogen-activated protein kinase involved in osmoregulation; controls global reallocation of RNAPII during osmotic shock; mediates recruitment/activation of RNAPII at Hot1p-dependent promoters; binds calmodulin; stimulates antisense transcription to activate CDC28; defines novel S-phase checkpoint with Mrc1p that prevent replication/transcription conflicts; nuclear form represses pseudohyphal growth; autophosphorylates; protein abundance increases under DNA replication stress [Source:SGD;Acc:S000004103]) HSP 1 Score: 155.221 bits (391), Expect = 1.657e-41 Identity = 104/332 (31.33%), Postives = 166/332 (50.00%), Query Frame = 3
Query: 60 KYYRNCITIMDKYNFVKQLGDGTYGSVILANVVGTSEKVAIKKMKKKFYSWDEC-LNLREVKSLRLLKHPNIIRLKEV-IRERDCLYLIFEYMNQNLYELIKSRNKPFPEEAIRNIIWQVLEGLTYIHKEGYFHRDLKPENILCNSATQIKLADFGLARSTRSAPPFTDYVATRWCLISLFFTVV*PCFDKPCDFRIHILFNSFLFRYRAPEVLLRSVNYNSPIDIFAVGCIMAELYTFRPLFPGSSEIDMIYKICCVLGTPNKNDWPEGQKLAGTMNFKFPTVTSTNLSVLIPSASR------DAIKIMLEMISWNPKNRPTSKDSLQYDY 1031
+ + I ++YN + +G G +G V A TS+ VAIKK+ K F + RE+K L+ L+H N+I L+++ + + +Y + E +L+ L+++R P ++ ++ ++Q+L GL Y+H G HRDLKP NIL N +K+ DFGLAR P T YV+TR+ YRAPE++L Y+ +DI++ GCI AE+ +PLFPG + I +LG+P K+ + KF VTS IP + R DA+ ++ +M+ ++PK R T+ D+L + Y
Sbjct: 11 QIFGTVFEITNRYNDLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTAVLAKRTYRELKLLKHLRHENLICLQDIFLSPLEDIYFVTELQGTDLHRLLQTR--PLEKQFVQYFLYQILRGLKYVHSAGVIHRDLKPSNILINENCDLKICDFGLARI--QDPQMTGYVSTRY--------------------------------YRAPEIMLTWQKYDVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVI---NTICSENTLKF--VTSLPHRDPIPFSERFKTVEPDAVDLLEKMLVFDPKKRITAADALAHPY 301
BLAST of Protein kinase domain-containing protein vs. Ensembl Nematostella
Match: EDO41147 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S560]) HSP 1 Score: 409.838 bits (1052), Expect = 4.233e-139 Identity = 193/329 (58.66%), Postives = 236/329 (71.73%), Query Frame = 3
Query: 87 MDKYNFVKQLGDGTYGSVILANVVGTSEKVAIKKMKKKFYSWDECLNLREVKSLRLLKHPNIIRLKEVIRERDCLYLIFEYMNQNLYELIKSRNKPFPEEAIRNIIWQVLEGLTYIHKEGYFHRDLKPENILCNSATQIKLADFGLARSTRSAPPFTDYVATRWCLISLFFTVV*PCFDKPCDFRIHILFNSFLFRYRAPEVLLRSVNYNSPIDIFAVGCIMAELYTFRPLFPGSSEIDMIYKICCVLGTPNKNDWPEGQKLAGTMNFKFPTVTSTNLSVLIPSASRDAIKIMLEMISWNPKNRPTSKDSLQYDYFKTNGQRSGQITTK 1073
M +Y +KQLGDGTYGSV LA + T E VAIKKMKKK++SWDEC+NLREVKSLR L H NI++LKEVIRE D LY +FEYM +NLY+++K+R+K PE IRN+I+Q+L+GL +IHK GYFHRD+KPEN+LC +K+ADFGLAR TRS PP+TDYV+TRW YRAPEVLLRS NY+SPIDI+AVGCIMAELYT RPLFPGSSE+D I+K+C VLG P ++WPEG KLA MNFKFP +T+L LIP+AS +AI++M EM+ WNPK RPT+ +L + YFK TTK
Sbjct: 1 MKRYQSIKQLGDGTYGSVELAKNIQTGETVAIKKMKKKYFSWDECINLREVKSLRKLSHTNIVKLKEVIRENDHLYFVFEYMKENLYQMMKNRDKLLPESVIRNVIYQILQGLAFIHKHGYFHRDMKPENLLCTGHELVKIADFGLARETRSRPPYTDYVSTRW--------------------------------YRAPEVLLRSTNYSSPIDIWAVGCIMAELYTLRPLFPGSSEVDEIFKVCSVLGPPKPDEWPEGHKLASAMNFKFPQTKATSLHSLIPNASAEAIQLMQEMLFWNPKKRPTAAQALHFPYFKVGQNLPKPQTTK 297
BLAST of Protein kinase domain-containing protein vs. Ensembl Nematostella
Match: EDO27671 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T8L4]) HSP 1 Score: 232.261 bits (591), Expect = 3.357e-72 Identity = 118/223 (52.91%), Postives = 147/223 (65.92%), Query Frame = 3
Query: 87 MDKYNFVKQLGDGTYGSVILANVVGTSEKVAIKK-MKKKFYSWDECLNLREVKSLRLLKHPNIIRLKEVIRERDCLYLIFEYMNQNLYELIKSRNKPFPEEAIRNIIWQVLEGLTYIHKEGYFHRDLKPENILCNSATQIKLADFGLARSTRSAPPFTDYVATRWCLISLFFTVV*PCFDKPCDFRIHILFNSFLFRYRAPEVLLRSVNYNSPIDIFAVGCIM 752
M +Y +KQLGDGTYGSV LA + T E VAIK +K + + L+ SLR L H NI++LKEVIRE D LY +FEYM +NLY+++K+R+K PE IRN+I+Q+L+GL +IHK GYFHRD+KPEN+LC +K+ADFGLAR TRS PP+TDYV+TRW YRAPEVLLRS NY+SPIDI+AVGCIM
Sbjct: 1 MKRYQSIKQLGDGTYGSVELAKNIQTGETVAIKNFLKVGHFQQNNHALLK--GSLRKLSHTNIVKLKEVIRENDHLYFVFEYMKENLYQMMKNRDKLLPESVIRNVIYQILQGLAFIHKHGYFHRDMKPENLLCTGHELVKIADFGLARETRSRPPYTDYVSTRW--------------------------------YRAPEVLLRSTNYSSPIDIWAVGCIM 189
BLAST of Protein kinase domain-containing protein vs. Ensembl Nematostella
Match: EDO40290 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S7S4]) HSP 1 Score: 203.756 bits (517), Expect = 3.738e-60 Identity = 110/317 (34.70%), Postives = 179/317 (56.47%), Query Frame = 3
Query: 96 YNFVKQLGDGTYGSVILANVVGTSEKVAIKKMKKKFYSWDECLNLREVKSLR-LLKHPNIIRLKEVIRERDC--LYLIFEYMNQNLYELIKSRNKPFPEEAIRNIIWQVLEGLTYIHKEGYFHRDLKPENILCNSATQIKLADFGLARSTRSAPPFTDYVATRWCLISLFFTVV*PCFDKPCDFRIHILFNSFLFRYRAPEVLLRSVNYNSPIDIFAVGCIMAELYTFRPLFPGSSEIDMIYKICCVLGTPNKNDWPEGQKLAGTMNFKFPTVTSTNLSVLIPSASRDAIKIMLEMISWNPKNRPTSKDSLQYDYFK 1037
Y + + G+GT+ V+ + A KKMK+++ S ++ NLRE++++R L H +++ LKE+I +R L LI E M+ NLYELI+ + PE +++ ++Q+L+ + + H+ G FHRD+KPENIL IKLAD G RS S P+T+Y++TRW YRAPE LL Y +D+++VGC+ E+ + PLFPGS+E+D I KI VLGTP + + + + MN+ FP T ++ L+P AS I+++ + +++P R ++K +L+++YF+
Sbjct: 2 YRILGKKGEGTFSEVLKVQDIRNGNYFACKKMKQQYDSLEQVNNLREIQAMRRLTPHAHVVELKEIIYDRKSGKLALIMELMDMNLYELIRGKRHYLPEAKVKSYMFQLLKSIDHAHRNGIFHRDVKPENILLKDDI-IKLADLGSCRSVYSKQPYTEYISTRW--------------------------------YRAPECLLTDGFYTHKMDLWSVGCVFFEIMSLHPLFPGSNEVDQIAKIHDVLGTPVPSILQKFKNKSRHMNYNFPQKKGTGINKLLPHASNMCIELIELLCTYDPDERISAKQALRHEYFR 285
BLAST of Protein kinase domain-containing protein vs. Ensembl Nematostella
Match: EDO48117 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RK70]) HSP 1 Score: 185.652 bits (470), Expect = 5.365e-53 Identity = 106/324 (32.72%), Postives = 168/324 (51.85%), Query Frame = 3
Query: 87 MDKYNFVKQLGDGTYGSVILANVVGTSEKVAIKKMKKKFYSWDECLNLREVKSLRLLKHPNIIRLKEVIRERDCLYLIFEYMNQNLYELIKSRNKPFPEEAIRNIIWQVLEGLTYIHKEGYFHRDLKPENILCNSATQIKLADFGLARSTRSAP--PFTDYVATRWCLISLFFTVV*PCFDKPCDFRIHILFNSFLFRYRAPEVLLRSVNYNSPIDIFAVGCIMAELYTFRPLFPGSSEIDMIYKICCVLGTPNKNDWPEGQKLAGTMNFKFPTVTSTNLSVLIPSASRDAIKIMLEMISWNPKNRPTSKDSLQYDYFKTNGQR 1052
M+ Y + +LG+GTY +V T VA+K+++ + C +REV L+ LKH NI+ L + + + L L+FEY+ ++L + + +R ++Q+L GL Y HK HRDLKP+N+L N ++KLADFGLAR+ +S P +++ V T W YR P+VLL S Y++ ID++ VGCI E+ T RPLFPGS+ D + I VLGTP++ WP + KFP NL + P ++++ + + + K+R ++ D++++DYF + G R
Sbjct: 8 METYTKLDKLGEGTYATVFKGKSKLTDNIVALKEIRLEHEEGAPCTAIREVSLLKGLKHANIVTLHDTVHTQKSLTLVFEYLEKDLKQYMDDCGGIMSMNNVRIFLFQLLRGLDYCHKRKVLHRDLKPQNLLINDKGELKLADFGLARA-KSVPTKTYSNEVVTLW--------------------------------YRPPDVLLGSTAYSTQIDMWGVGCIFFEMATGRPLFPGSTVEDELLLIFKVLGTPSEEVWPGISANEAFIAGKFPDYPRENLIIHAPRLDNSGLELLEKFLEYTVKDRVSAHDAMRHDYFYSLGTR 298
BLAST of Protein kinase domain-containing protein vs. Ensembl Nematostella
Match: EDO41403 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S4F0]) HSP 1 Score: 182.185 bits (461), Expect = 4.839e-52 Identity = 107/323 (33.13%), Postives = 172/323 (53.25%), Query Frame = 3
Query: 87 MDKYNFVKQLGDGTYGSVILANVVGTSEKVAIKKMKKKFYSWD-ECLNLREVKSLRLLKHPNIIRLKEVIRERDCLYLIFEYMNQNLYELIKS-RNKPFPEEAIRNIIWQVLEGLTYIHKEGYFHRDLKPENILCNSATQIKLADFGLARS----TRSAPPFTDYVATRWCLISLFFTVV*PCFDKPCDFRIHILFNSFLFRYRAPEVLLRSVNYNSPIDIFAVGCIMAELYTFRPLFPGSSEIDMIYKICCVLGTPNKNDWPEGQKLAGTMNFKFPTVTSTNLSVLIPSASRDAIKIMLEMISWNPKNRPTSKDSLQYDYFK 1037
M+ + V+++G+GTYG V A T VA+KK++ S +RE+ L+ L HPN++ L +V+ + LYL+FE+++Q+L + + I++ ++Q+L G+ Y H HRDLKP+N+L + IKLADFGLAR+ RS +T V T W YRAPE+LL S Y +P+D++++GCI AE+ T R LFPG SEID +++I LGTP+ WP +L FP ++ ++P+ AI ++ +M+++ P R ++K +L +++FK
Sbjct: 1 MENFEKVEKIGEGTYGVVYKARDKTTGRMVALKKIRLDTESEGVPSTAIREISLLKELNHPNVVSLLDVVHNQKSLYLVFEFLSQDLKKYMDCLPPSGISTSLIKSYVYQLLSGVAYCHSHRVLHRDLKPQNLLIDKNGAIKLADFGLARAFGVPVRS---YTHEVVTLW--------------------------------YRAPEILLGSRYYATPVDVWSIGCIFAEMKTRRALFPGDSEIDQLFRIFRTLGTPDDKVWPGVSELPDYKT-SFPKWPVQSIRHVLPTLDNTAIDLLQKMLTYQPNARISAKAALSHEFFK 287
BLAST of Protein kinase domain-containing protein vs. Ensembl Medaka
Match: mak (male germ cell associated kinase [Source:NCBI gene;Acc:101162081]) HSP 1 Score: 394.045 bits (1011), Expect = 1.294e-128 Identity = 196/376 (52.13%), Postives = 249/376 (66.22%), Query Frame = 3
Query: 87 MDKYNFVKQLGDGTYGSVILANVVGTSEKVAIKKMKKKFYSWDECLNLREVKSLRLLKHPNIIRLKEVIRERDCLYLIFEYMNQNLYELIKSRNKPFPEEAIRNIIWQVLEGLTYIHKEGYFHRDLKPENILCNSATQIKLADFGLARSTRSAPPFTDYVATRWCLISLFFTVV*PCFDKPCDFRIHILFNSFLFRYRAPEVLLRSVNYNSPIDIFAVGCIMAELYTFRPLFPGSSEIDMIYKICCVLGTPNKNDWPEGQKLAGTMNFKFPTVTSTNLSVLIPSASRDAIKIMLEMISWNPKNRPTSKDSLQYDYFKTNGQRSGQITTKRP----LTNVQNTSNLNIDMPTINNIMTINQN-KPKTDPILDKSDRR 1199
M++Y +KQLGDGTYGSV++ + E VAIK+MKKKFYSWDEC+NLREVKSL+ L H N+++LKEVIRE D LY +FEYM +NLY+L+K R K FPE IRNI +Q+L+GL++IHK G+FHRD+KPEN+LC +K+ADFGLAR RS PP+TDYV+TRW YRAPEVLLRS Y SPID++AVGCIMAELYT RPLFPG+SE+D I+KIC VLGT K +WPEG +LA MNF+FP T+L LIP+AS +AI +M + + W+PK RPT+ +L+Y YF+ GQ+ RP L +QN S M QN + KTDP+ S+ +
Sbjct: 1 MNRYTTLKQLGDGTYGSVLMGRNNESGEYVAIKRMKKKFYSWDECMNLREVKSLKKLNHANVVKLKEVIRENDHLYFVFEYMKENLYQLMKDRIKKFPESVIRNISFQILQGLSFIHKHGFFHRDMKPENLLCMGPELVKIADFGLAREIRSKPPYTDYVSTRW--------------------------------YRAPEVLLRSSTYGSPIDLWAVGCIMAELYTLRPLFPGNSEMDEIFKICQVLGTVKKTEWPEGYQLASAMNFRFPQCVPTHLKTLIPNASNEAIALMKDFLQWDPKKRPTAAQALRYPYFQV-----GQVLGPRPQSQELKKMQNRS------------MVKKQNSESKTDPLQSSSESK 327
BLAST of Protein kinase domain-containing protein vs. Ensembl Medaka
Match: ICK (ciliogenesis associated kinase 1 [Source:NCBI gene;Acc:101174616]) HSP 1 Score: 395.586 bits (1015), Expect = 3.478e-128 Identity = 185/324 (57.10%), Postives = 232/324 (71.60%), Query Frame = 3
Query: 87 MDKYNFVKQLGDGTYGSVILANVVGTSEKVAIKKMKKKFYSWDECLNLREVKSLRLLKHPNIIRLKEVIRERDCLYLIFEYMNQNLYELIKSRNKPFPEEAIRNIIWQVLEGLTYIHKEGYFHRDLKPENILCNSATQIKLADFGLARSTRSAPPFTDYVATRWCLISLFFTVV*PCFDKPCDFRIHILFNSFLFRYRAPEVLLRSVNYNSPIDIFAVGCIMAELYTFRPLFPGSSEIDMIYKICCVLGTPNKNDWPEGQKLAGTMNFKFPTVTSTNLSVLIPSASRDAIKIMLEMISWNPKNRPTSKDSLQYDYFKTNGQRSG 1058
M++Y ++QLGDGTYGSVIL + + E VAIKKMK+KFYSW+EC+NLREVKSL+ L H N+I+LKEVIRE D LY IFEYM +NLY+L+K R + FPE A+RNI++Q+L+GL +IHK G+FHRD+KPEN+LC +K+ADFGLAR RS PP+TDYV+TRW YRAPEVLLRS +Y+SPID +AVGCIMAELYT RPLFPGSSE+D I+KIC VLGTP K DWPEG +LA MNF++P +NL LIP+AS +AI +M + + W+P+ RP S +L+Y YF GQ G
Sbjct: 1 MNRYTNIRQLGDGTYGSVILGRSLESGELVAIKKMKRKFYSWEECMNLREVKSLKKLNHANVIKLKEVIRENDHLYFIFEYMKENLYQLMKDRTRLFPESAVRNIMFQILQGLAFIHKHGFFHRDMKPENLLCMGPELVKIADFGLAREIRSRPPYTDYVSTRW--------------------------------YRAPEVLLRSTSYSSPIDQWAVGCIMAELYTLRPLFPGSSEVDTIFKICQVLGTPKKTDWPEGYQLASAMNFRWPQCVPSNLKTLIPNASAEAIHLMTDFLQWDPRKRPASAQALRYSYFHV-GQALG 291
BLAST of Protein kinase domain-containing protein vs. Ensembl Medaka
Match: mak (male germ cell associated kinase [Source:NCBI gene;Acc:101162081]) HSP 1 Score: 393.66 bits (1010), Expect = 2.554e-127 Identity = 196/377 (51.99%), Postives = 250/377 (66.31%), Query Frame = 3
Query: 84 IMDKYNFVKQLGDGTYGSVILANVVGTSEKVAIKKMKKKFYSWDECLNLREVKSLRLLKHPNIIRLKEVIRERDCLYLIFEYMNQNLYELIKSRNKPFPEEAIRNIIWQVLEGLTYIHKEGYFHRDLKPENILCNSATQIKLADFGLARSTRSAPPFTDYVATRWCLISLFFTVV*PCFDKPCDFRIHILFNSFLFRYRAPEVLLRSVNYNSPIDIFAVGCIMAELYTFRPLFPGSSEIDMIYKICCVLGTPNKNDWPEGQKLAGTMNFKFPTVTSTNLSVLIPSASRDAIKIMLEMISWNPKNRPTSKDSLQYDYFKTNGQRSGQITTKRP----LTNVQNTSNLNIDMPTINNIMTINQN-KPKTDPILDKSDRR 1199
+M++Y +KQLGDGTYGSV++ + E VAIK+MKKKFYSWDEC+NLREVKSL+ L H N+++LKEVIRE D LY +FEYM +NLY+L+K R K FPE IRNI +Q+L+GL++IHK G+FHRD+KPEN+LC +K+ADFGLAR RS PP+TDYV+TRW YRAPEVLLRS Y SPID++AVGCIMAELYT RPLFPG+SE+D I+KIC VLGT K +WPEG +LA MNF+FP T+L LIP+AS +AI +M + + W+PK RPT+ +L+Y YF+ GQ+ RP L +QN S M QN + KTDP+ S+ +
Sbjct: 1 MMNRYTTLKQLGDGTYGSVLMGRNNESGEYVAIKRMKKKFYSWDECMNLREVKSLKKLNHANVVKLKEVIRENDHLYFVFEYMKENLYQLMKDRIKKFPESVIRNISFQILQGLSFIHKHGFFHRDMKPENLLCMGPELVKIADFGLAREIRSKPPYTDYVSTRW--------------------------------YRAPEVLLRSSTYGSPIDLWAVGCIMAELYTLRPLFPGNSEMDEIFKICQVLGTVKKTEWPEGYQLASAMNFRFPQCVPTHLKTLIPNASNEAIALMKDFLQWDPKKRPTAAQALRYPYFQV-----GQVLGPRPQSQELKKMQNRS------------MVKKQNSESKTDPLQSSSESK 328
BLAST of Protein kinase domain-containing protein vs. Ensembl Medaka
Match: mak (male germ cell associated kinase [Source:NCBI gene;Acc:101162081]) HSP 1 Score: 394.43 bits (1012), Expect = 3.201e-127 Identity = 196/377 (51.99%), Postives = 250/377 (66.31%), Query Frame = 3
Query: 84 IMDKYNFVKQLGDGTYGSVILANVVGTSEKVAIKKMKKKFYSWDECLNLREVKSLRLLKHPNIIRLKEVIRERDCLYLIFEYMNQNLYELIKSRNKPFPEEAIRNIIWQVLEGLTYIHKEGYFHRDLKPENILCNSATQIKLADFGLARSTRSAPPFTDYVATRWCLISLFFTVV*PCFDKPCDFRIHILFNSFLFRYRAPEVLLRSVNYNSPIDIFAVGCIMAELYTFRPLFPGSSEIDMIYKICCVLGTPNKNDWPEGQKLAGTMNFKFPTVTSTNLSVLIPSASRDAIKIMLEMISWNPKNRPTSKDSLQYDYFKTNGQRSGQITTKRP----LTNVQNTSNLNIDMPTINNIMTINQN-KPKTDPILDKSDRR 1199
+M++Y +KQLGDGTYGSV++ + E VAIK+MKKKFYSWDEC+NLREVKSL+ L H N+++LKEVIRE D LY +FEYM +NLY+L+K R K FPE IRNI +Q+L+GL++IHK G+FHRD+KPEN+LC +K+ADFGLAR RS PP+TDYV+TRW YRAPEVLLRS Y SPID++AVGCIMAELYT RPLFPG+SE+D I+KIC VLGT K +WPEG +LA MNF+FP T+L LIP+AS +AI +M + + W+PK RPT+ +L+Y YF+ GQ+ RP L +QN S M QN + KTDP+ S+ +
Sbjct: 1 MMNRYTTLKQLGDGTYGSVLMGRNNESGEYVAIKRMKKKFYSWDECMNLREVKSLKKLNHANVVKLKEVIRENDHLYFVFEYMKENLYQLMKDRIKKFPESVIRNISFQILQGLSFIHKHGFFHRDMKPENLLCMGPELVKIADFGLAREIRSKPPYTDYVSTRW--------------------------------YRAPEVLLRSSTYGSPIDLWAVGCIMAELYTLRPLFPGNSEMDEIFKICQVLGTVKKTEWPEGYQLASAMNFRFPQCVPTHLKTLIPNASNEAIALMKDFLQWDPKKRPTAAQALRYPYFQV-----GQVLGPRPQSQELKKMQNRS------------MVKKQNSESKTDPLQSSSESK 328
BLAST of Protein kinase domain-containing protein vs. Ensembl Medaka
Match: mak (male germ cell associated kinase [Source:NCBI gene;Acc:101162081]) HSP 1 Score: 389.037 bits (998), Expect = 3.558e-125 Identity = 196/378 (51.85%), Postives = 249/378 (65.87%), Query Frame = 3
Query: 84 IMDKYNFVKQLGDGTYGSVILANVVGTSEKVAIKKMKKKFYSWDECLNLREVKSLRLLKHPNIIRLKEVIRERDCLYLIFEYMNQNLYELIKSR-NKPFPEEAIRNIIWQVLEGLTYIHKEGYFHRDLKPENILCNSATQIKLADFGLARSTRSAPPFTDYVATRWCLISLFFTVV*PCFDKPCDFRIHILFNSFLFRYRAPEVLLRSVNYNSPIDIFAVGCIMAELYTFRPLFPGSSEIDMIYKICCVLGTPNKNDWPEGQKLAGTMNFKFPTVTSTNLSVLIPSASRDAIKIMLEMISWNPKNRPTSKDSLQYDYFKTNGQRSGQITTKRP----LTNVQNTSNLNIDMPTINNIMTINQN-KPKTDPILDKSDRR 1199
+M++Y +KQLGDGTYGSV++ + E VAIK+MKKKFYSWDEC+NLREVKSL+ L H N+++LKEVIRE D LY +FEYM +NLY+L+K R NK F E IRNI++QVL GL ++HK G+FHRD+KPEN+LC +K+ADFGLAR RS PP+TDYV+TRW YRAPEVLLRS Y SPID++AVGCIMAELYT RPLFPG+SE+D I+KIC VLGT K +WPEG +LA MNF+FP T+L LIP+AS +AI +M + + W+PK RPT+ +L+Y YF+ GQ+ RP L +QN S M QN + KTDP+ S+ +
Sbjct: 1 MMNRYTTLKQLGDGTYGSVLMGRNNESGEYVAIKRMKKKFYSWDECMNLREVKSLKKLNHANVVKLKEVIRENDHLYFVFEYMKENLYQLMKDRENKMFSENEIRNILFQVLSGLAFVHKHGFFHRDMKPENLLCMGPELVKIADFGLAREIRSKPPYTDYVSTRW--------------------------------YRAPEVLLRSSTYGSPIDLWAVGCIMAELYTLRPLFPGNSEMDEIFKICQVLGTVKKTEWPEGYQLASAMNFRFPQCVPTHLKTLIPNASNEAIALMKDFLQWDPKKRPTAAQALRYPYFQV-----GQVLGPRPQSQELKKMQNRS------------MVKKQNSESKTDPLQSSSESK 329
BLAST of Protein kinase domain-containing protein vs. Planmine SMEST
Match: SMESG000039711.1 (SMESG000039711.1) HSP 1 Score: 1159.44 bits (2998), Expect = 0.000e+0 Identity = 613/648 (94.60%), Postives = 615/648 (94.91%), Query Frame = 3
Query: 87 MDKYNFVKQLGDGTYGSVILANVVGTSEKVAIKKMKKKFYSWDECLNLREVKSLRLLKHPNIIRLKEVIRERDCLYLIFEYMNQNLYELIKSRNKPFPEEAIRNIIWQVLEGLTYIHKEGYFHRDLKPENILCNSATQIKLADFGLARSTRSAPPFTDYVATRWCLISLFFTVV*PCFDKPCDFRIHILFNSFLFRYRAPEVLLRSVNYNSPIDIFAVGCIMAELYTFRPLFPGSSEIDMIYKICCVLGTPNKNDWPEGQKLAGTMNFKFPTVTSTNLSVLIPSASRDAIKIMLEMISWNPKNRPTSKDSLQYDYFKTNGQRSGQITTKRPLTNVQNTSNLNIDMPTINNIMTINQNKPKTDPILDKSDRRKWAPMEFSDDWDFDIGTSKNHFSKPVKNEPNPSEIKRQKAFDEFDFDMSFIAEMNSKSPQRRKSTKRESXXXXXXLESINNKSKITQKNDITSGKENMGPFVSGTQRRPSVNKGSASSFYKSNARYHVGMNPRNSGNNQFNGVLXXXXXXXXXXXXXXXXXYEQSVFNSKPNSSNFFDDHYPWKVGSATKSNFPIGQNHTVLPSIGQSNNAKTDNFQFXXXXXXXXXXTEDPLIPNFPGGNRKSSVKKPSDVNRYFPGQNNVNRSNRTDWAAKYLKS 2030
MDKYNFVKQLGDGTYGSVILANVVGTSEKVAIKKMKKKFYSWDECLNLREVKSLRLLKHPNIIRLKEVIRERDCLYLIFEYMNQNLYELIKSRNKPFPEEAIRNIIWQVLEGLTYIHKEGYFHRDLKPENILCNSATQIKLADFGLARSTRSAPPFTDYVATRW YRAPEVLLRSVNYNSPIDIFAVGCIMAELYTFRPLFPGSSEIDMIYKICCVLGTPNKNDWPEGQKLAGTMNFKFPTVTSTNLSVLIPSASRDAIKIMLEMISWNPKNRPTSKDSLQYDYFKTNGQRSGQITTKRPLTNVQNTSNLNIDMPTINNIMTINQNKPKTDPILDK DRRKWAPMEFSDDWDFDIGTSKNHFSKPVKNEPNPSEIKRQKAFDEFDF+MSFIAEMNSKSPQRRKSTKRESIDIDDILESINNKSKITQKNDITSGKEN+GPFVSGTQRRPSVNKGSASSFYKSNARYHVGMNPRNSGNNQFNGVLPKIPPISSEISKPSDSKYEQSVFNSKPNSSNFFDDHYPWKVGSATKSNFPIGQNHTVLPSIGQSNNAKTDNFQFSSKSSIKSIKTEDPLIPNFPGGNRKSSVKKPSDVNRYFPGQNNVNRSNRTDWAAKYLKS
Sbjct: 1 MDKYNFVKQLGDGTYGSVILANVVGTSEKVAIKKMKKKFYSWDECLNLREVKSLRLLKHPNIIRLKEVIRERDCLYLIFEYMNQNLYELIKSRNKPFPEEAIRNIIWQVLEGLTYIHKEGYFHRDLKPENILCNSATQIKLADFGLARSTRSAPPFTDYVATRW--------------------------------YRAPEVLLRSVNYNSPIDIFAVGCIMAELYTFRPLFPGSSEIDMIYKICCVLGTPNKNDWPEGQKLAGTMNFKFPTVTSTNLSVLIPSASRDAIKIMLEMISWNPKNRPTSKDSLQYDYFKTNGQRSGQITTKRPLTNVQNTSNLNIDMPTINNIMTINQNKPKTDPILDKPDRRKWAPMEFSDDWDFDIGTSKNHFSKPVKNEPNPSEIKRQKAFDEFDFEMSFIAEMNSKSPQRRKSTKRESIDIDDILESINNKSKITQKNDITSGKENIGPFVSGTQRRPSVNKGSASSFYKSNARYHVGMNPRNSGNNQFNGVLPKIPPISSEISKPSDSKYEQSVFNSKPNSSNFFDDHYPWKVGSATKSNFPIGQNHTVLPSIGQSNNAKTDNFQFSSKSSIKSIKTEDPLIPNFPGGNRKSSVKKPSDVNRYFPGQNNVNRSNRTDWAAKYLKS 616
BLAST of Protein kinase domain-containing protein vs. Planmine SMEST
Match: SMESG000039711.1 (SMESG000039711.1) HSP 1 Score: 1136.32 bits (2938), Expect = 0.000e+0 Identity = 598/648 (92.28%), Postives = 609/648 (93.98%), Query Frame = 3
Query: 87 MDKYNFVKQLGDGTYGSVILANVVGTSEKVAIKKMKKKFYSWDECLNLREVKSLRLLKHPNIIRLKEVIRERDCLYLIFEYMNQNLYELIKSRNKPFPEEAIRNIIWQVLEGLTYIHKEGYFHRDLKPENILCNSATQIKLADFGLARSTRSAPPFTDYVATRWCLISLFFTVV*PCFDKPCDFRIHILFNSFLFRYRAPEVLLRSVNYNSPIDIFAVGCIMAELYTFRPLFPGSSEIDMIYKICCVLGTPNKNDWPEGQKLAGTMNFKFPTVTSTNLSVLIPSASRDAIKIMLEMISWNPKNRPTSKDSLQYDYFKTNGQRSGQITTKRPLTNVQNTSNLNIDMPTINNIMTINQNKPKTDPILDKSDRRKWAPMEFSDDWDFDIGTSKNHFSKPVKNEPNPSEIKRQKAFDEFDFDMSFIAEMNSKSPQRRKSTKRESXXXXXXLESINNKSKITQKNDITSGKENMGPFVSGTQRRPSVNKGSASSFYKSNARYHVGMNPRNSGNNQFNGVLXXXXXXXXXXXXXXXXXYEQSVFNSKPNSSNFFDDHYPWKVGSATKSNFPIGQNHTVLPSIGQSNNAKTDNFQFXXXXXXXXXXTEDPLIPNFPGGNRKSSVKKPSDVNRYFPGQNNVNRSNRTDWAAKYLKS 2030
MDKYNFVKQLGDGTYGSVILANVVGTSEKVAIKKMKKKFYSWDECLNLREVKSLRLLKHPNIIRLKEVIRERDCLYLIFEYMNQNLYELIKSRNKPFPEEAIRNIIWQVLEGLTYIHKEG+FHRD+KPEN++CN + +K+ADFGLAR RS PP+TDYV+TRW YRAPEVLLRSVNYNSPIDIFAVGCIMAELYTFRPLFPGSSEIDMIYKICCVLGTPNKNDWPEGQKLAGTMNFKFPTVTSTNLSVLIPSASRDAIKIMLEMISWNPKNRPTSKDSLQYDYFKTNGQRSGQITTKRPLTNVQNTSNLNIDMPTINNIMTINQNKPKTDPILDK DRRKWAPMEFSDDWDFDIGTSKNHFSKPVKNEPNPSEIKRQKAFDEFDF+MSFIAEMNSKSPQRRKSTKRESIDIDDILESINNKSKITQKNDITSGKEN+GPFVSGTQRRPSVNKGSASSFYKSNARYHVGMNPRNSGNNQFNGVLPKIPPISSEISKPSDSKYEQSVFNSKPNSSNFFDDHYPWKVGSATKSNFPIGQNHTVLPSIGQSNNAKTDNFQFSSKSSIKSIKTEDPLIPNFPGGNRKSSVKKPSDVNRYFPGQNNVNRSNRTDWAAKYLKS
Sbjct: 1 MDKYNFVKQLGDGTYGSVILANVVGTSEKVAIKKMKKKFYSWDECLNLREVKSLRLLKHPNIIRLKEVIRERDCLYLIFEYMNQNLYELIKSRNKPFPEEAIRNIIWQVLEGLTYIHKEGFFHRDMKPENLMCNGSECVKIADFGLAREVRSQPPYTDYVSTRW--------------------------------YRAPEVLLRSVNYNSPIDIFAVGCIMAELYTFRPLFPGSSEIDMIYKICCVLGTPNKNDWPEGQKLAGTMNFKFPTVTSTNLSVLIPSASRDAIKIMLEMISWNPKNRPTSKDSLQYDYFKTNGQRSGQITTKRPLTNVQNTSNLNIDMPTINNIMTINQNKPKTDPILDKPDRRKWAPMEFSDDWDFDIGTSKNHFSKPVKNEPNPSEIKRQKAFDEFDFEMSFIAEMNSKSPQRRKSTKRESIDIDDILESINNKSKITQKNDITSGKENIGPFVSGTQRRPSVNKGSASSFYKSNARYHVGMNPRNSGNNQFNGVLPKIPPISSEISKPSDSKYEQSVFNSKPNSSNFFDDHYPWKVGSATKSNFPIGQNHTVLPSIGQSNNAKTDNFQFSSKSSIKSIKTEDPLIPNFPGGNRKSSVKKPSDVNRYFPGQNNVNRSNRTDWAAKYLKS 616
BLAST of Protein kinase domain-containing protein vs. Planmine SMEST
Match: SMESG000043386.1 (SMESG000043386.1) HSP 1 Score: 213.386 bits (542), Expect = 4.277e-61 Identity = 115/328 (35.06%), Postives = 189/328 (57.62%), Query Frame = 3
Query: 84 IMDKYNFVKQLGDGTYGSVILANVVGTSEKVAIKKMKKKFYSWDECLNLREVKSLRLLK-HPNIIRLKEVI--RERDCLYLIFEYMNQNLYELIKSRNKPFPEEAIRNIIWQVLEGLTYIHKEGYFHRDLKPENILCNSATQIKLADFGLARSTRSAPPFTDYVATRWCLISLFFTVV*PCFDKPCDFRIHILFNSFLFRYRAPEVLLRSVNYNSPIDIFAVGCIMAELYTFRPLFPGSSEIDMIYKICCVLGTPNKNDWPEGQKLAGTMNFKFPTVTSTNLSVLIPSASRDAIKIMLEMISWNPKNRPTSKDSLQYDYFKTNGQRSG 1058
++ + + + G+GT+ V+ V + A KKMK+ + +WD+ NLRE++++R L H NI+ L EV+ ++ L LI E M+ NLYELIK R PE ++ +WQ+++GL +IHK G FHRD+KPENIL + +K+ADFG ++ S P+T+Y++TRW YRAPE LL Y+ +D+++VGC+M E+ + RPLFPG++E+D I KI +LG+P+ + +K + +++F FP + + L+ S +A+ I+ ++I ++P R T++++L + YFK SG
Sbjct: 1 MIKDFRLISKKGEGTFSEVLKCQNVKNKDYFACKKMKQHYETWDQVNNLREIQAMRRLNPHENILLLHEVVFDKKSGTLCLILELMDMNLYELIKGRKNYLPEHDVKRYMWQLIQGLFHIHKNGIFHRDVKPENILIRDQS-LKIADFGSCKTIFSRYPYTEYISTRW--------------------------------YRAPECLLTDGYYSYQMDLWSVGCVMFEILSLRPLFPGANEVDQIGKIHDILGSPDASILKNFKK-SRSVSFNFPIRKGSGIERLLAHVSLEAVSIIKQLIEYDPSRRLTTQNALNHPYFKELRSNSG 294
BLAST of Protein kinase domain-containing protein vs. Planmine SMEST
Match: SMESG000052413.1 (SMESG000052413.1) HSP 1 Score: 181.03 bits (458), Expect = 5.926e-51 Identity = 109/321 (33.96%), Postives = 172/321 (53.58%), Query Frame = 3
Query: 87 MDKYNFVKQLGDGTYGSVILANVVGTSEKVAIKKMKKKFYSWDE----CLNLREVKSLRLLKHPNIIRLKEVIRERDCLYLIFEYMNQNLYELIKSRNKPFPEEAIRNIIWQVLEGLTYIHKEGYFHRDLKPENILCNSATQ-IKLADFGLARSTRSAPPFTDYVATRWCLISLFFTVV*PCFDKPCDFRIHILFNSFLFRYRAPEVLLRSVNYNSPIDIFAVGCIMAELYTFRPLFPGSSEIDMIYKICCVLGTPNKNDWPEGQKLAGTMNFKFPTVTSTNLSVLIPSASRDAIKIMLEMISWNPKNRPTSKDSLQYDYF 1034
+ + ++++G+GTYG V + T+E AIKK++ + DE LRE+ L+ L+HPNI+ L++ I E+ LYL+FEY+N +L + + P + ++ +Q+++GL Y H + HRDLKP+N+L ++ IKLADFGLAR C+ P H + + YRAPEV+L + Y+ ID+++V CIMAE+ T++PLF G SEID ++ I VLGTP+ WP+ K G N FP S L+ + ++ +M+ ++P R +D+L +DYF
Sbjct: 5 LSDFTRIEKIGEGTYGIVYKSINKITNEFAAIKKIRSEN---DEDGIAPTTLREISILKELRHPNIVYLQQTIAEKGKLYLVFEYLNMDLRRYLDNEENPMNDIILKKFSYQIMQGLLYCHTRRFMHRDLKPQNLLVDTNKHIIKLADFGLAR----------------------------CYGAPVKNLTHEVVTLW---YRAPEVILNAKRYSCAIDVWSVACIMAEMITYKPLFRGDSEIDQLFAIFKVLGTPDNKVWPDLDKFPG-WNPLFPVWRYDLRSRLVEVIDENLFDLLEKMLVYHPLERTNIRDALLHDYF 290
BLAST of Protein kinase domain-containing protein vs. Planmine SMEST
Match: SMESG000052421.1 (SMESG000052421.1) HSP 1 Score: 177.563 bits (449), Expect = 1.416e-49 Identity = 111/318 (34.91%), Postives = 168/318 (52.83%), Query Frame = 3
Query: 105 VKQLGDGTYGSVILANVVGTSEKVAIKKMKKKFYSWDE----CLNLREVKSLRLLKHPNIIRLKEVIRERDCLYLIFEYMNQNLYELIKSRNKPFPEEAIRNIIWQVLEGLTYIHKEGYFHRDLKPENILCNS-ATQIKLADFGLARSTRSAP--PFTDYVATRWCLISLFFTVV*PCFDKPCDFRIHILFNSFLFRYRAPEVLLRSVNYNSPIDIFAVGCIMAELYTFRPLFPGSSEIDMIYKICCVLGTPNKNDWPEGQKLAGTMNFKFPTVTSTNL-SVLIPSASRDAIKIMLEMISWNPKNRPTSKDSLQYDYF 1034
++++G+GTYG V T + A+KK++ + DE +RE+ L+ L HPNI+ LK+ + + L+L+FEY+N +L + + I+ ++Q+L+GL + H HRDLKP+N+L ++ T IKLADFGLAR T P T V T W YRAPE+L+ S Y+ +D+++V CI AE+ T +PLF G SEID I+KI +LGTP +N WP G + N P T++ L S S D + ++ EM+ +NP +R S+D+L + YF
Sbjct: 18 IEKIGEGTYGVVYKGKNKKTGDFAALKKIRLEN---DEDGVPSTAIREISLLKELIHPNIVTLKQSMMQDGKLFLVFEYLNMDLRRYLDNLQCSMDPMVIKCFVYQILQGLLFCHLRRVIHRDLKPQNLLVDATGTIIKLADFGLAR-TFGVPVKALTHEVVTLW--------------------------------YRAPEILMGSKRYSCAVDVWSVACIFAEMATTKPLFRGDSEIDQIFKIFHLLGTPTENHWP-GVSHLSSWNSMLPLWTTSRLCSHFKDFMSPDGLDLISEMLLYNPPDRINSRDALLHSYF 298 The following BLAST results are available for this feature:
BLAST of Protein kinase domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Protein kinase domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Protein kinase domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Protein kinase domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Protein kinase domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Protein kinase domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Protein kinase domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Protein kinase domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Protein kinase domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Protein kinase domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of Protein kinase domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 5
BLAST of Protein kinase domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Protein kinase domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Protein kinase domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30009210 ID=SMED30009210|Name=Protein kinase domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=2172bpback to top protein sequence of SMED30009210-orf-1 >SMED30009210-orf-1 ID=SMED30009210-orf-1|Name=SMED30009210-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=428bp MAELYTFRPLFPGSSEIDMIYKICCVLGTPNKNDWPEGQKLAGTMNFKFPback to top protein sequence of SMED30009210-orf-2 >SMED30009210-orf-2 ID=SMED30009210-orf-2|Name=SMED30009210-orf-2|organism=Schmidtea mediterranea sexual|type=polypeptide|length=175bp MDKYNFVKQLGDGTYGSVILANVVGTSEKVAIKKMKKKFYSWDECLNLREback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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