Transcription elongation factor spt6

Overview
NameTranscription elongation factor spt6
Smed IDSMED30009175
Length (bp)966
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Transcription elongation factor spt6 (SMED30009175) t-SNE clustered cells

Violin plots show distribution of expression levels for Transcription elongation factor spt6 (SMED30009175) in cells (dots) of each of the 12 neoblast clusters.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30009175

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 16

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
pharynxSMED30009175h1SMcG0007554 Contig5500uc_Smed_v2PMID:23079596
Forsthoefel et al., 2012		whole organism asexual adult colorimetric in situ hybridization evidence
pharynxSMED30009175h1SMcG0007554 Contig5500newmark_estsPMID:23079596
Forsthoefel et al., 2012		whole organism asexual adult colorimetric in situ hybridization evidence
gutSMED30009175h1SMcG0007554 Contig5500uc_Smed_v2PMID:23079596
Forsthoefel et al., 2012		whole organism asexual adult colorimetric in situ hybridization evidence
gutSMED30009175h1SMcG0007554 Contig5500newmark_estsPMID:23079596
Forsthoefel et al., 2012		whole organism asexual adult colorimetric in situ hybridization evidence
intestinal phagocyteSMED30009175h1SMcG0007554 Contig5500uc_Smed_v2PMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
intestinal phagocyteSMED30009175h1SMcG0007554 Contig5500newmark_estsPMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
central nervous systemSMED30009175h1SMcG0007554 Contig5500uc_Smed_v2PMID:23079596
Forsthoefel et al., 2012		whole organism asexual adult colorimetric in situ hybridization evidence
central nervous systemSMED30009175h1SMcG0007554 Contig5500newmark_estsPMID:23079596
Forsthoefel et al., 2012		whole organism asexual adult colorimetric in situ hybridization evidence
pharynxSMED30009175h1SMcG0013620 Contig5500uc_Smed_v2PMID:23079596
Forsthoefel et al., 2012		whole organism asexual adult colorimetric in situ hybridization evidence
pharynxSMED30009175h1SMcG0013620 Contig5500newmark_estsPMID:23079596
Forsthoefel et al., 2012		whole organism asexual adult colorimetric in situ hybridization evidence
gutSMED30009175h1SMcG0013620 Contig5500uc_Smed_v2PMID:23079596
Forsthoefel et al., 2012		whole organism asexual adult colorimetric in situ hybridization evidence
gutSMED30009175h1SMcG0013620 Contig5500newmark_estsPMID:23079596
Forsthoefel et al., 2012		whole organism asexual adult colorimetric in situ hybridization evidence
intestinal phagocyteSMED30009175h1SMcG0013620 Contig5500uc_Smed_v2PMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
intestinal phagocyteSMED30009175h1SMcG0013620 Contig5500newmark_estsPMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
central nervous systemSMED30009175h1SMcG0013620 Contig5500uc_Smed_v2PMID:23079596
Forsthoefel et al., 2012		whole organism asexual adult colorimetric in situ hybridization evidence
central nervous systemSMED30009175h1SMcG0013620 Contig5500newmark_estsPMID:23079596
Forsthoefel et al., 2012		whole organism asexual adult colorimetric in situ hybridization evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Transcription elongation factor spt6 vs. Ensembl Human
Match: SUPT6H (SPT6 homolog, histone chaperone and transcription elongation factor [Source:HGNC Symbol;Acc:HGNC:11470])

HSP 1 Score: 225.713 bits (574), Expect = 8.999e-66
Identity = 118/322 (36.65%), Postives = 187/322 (58.07%), Query Frame = 1 
Query:    1 QDHRPRFISLTEQERFYFLTNENEETLKIGTVAEFRVINVVNRRNQKD-FDNANPKGNKDTGMFSCPICQEDNFHQLSEIWVHFDN-QCPGKAVGVNLLFENQIMTFVSIRNIADKFVRNVYDFVKVDQLVVGVVTNISYSKMKLEASLKQSDIKKAFEREKGRRDPHYDEKAENDEKSRKTKHKPSKNNKPIATNTRVSFHPNFKNLNYEQFMKMSHTLRANDFIIRPSSKGPNRLSISWKLSSNLFRHIDVKEEEKKNEFTIGQVLFIDSERFEDLDDIIANYLQPMIGYVDEIFTHKYFKDIRAEDKVTLERMIFEDKR 960
            +D R  + S   +E F  LT E  ET  IG +    V  + +RR Q + +D A    N +TG++ CP CQ+DNF +LSE+W HFD+  CPG+A+GV    +N +  F+  + ++DK V+   + VKV   V   +  I   K   + + + SD+       K  +D +YD  AE  +  ++   K  +  +      RV  HP+F N+N++Q  KM  T+   D IIRPSSKG N L+++WK+S  +++H+DV+EE K+N F++G  L+I+SE FEDLD+I+A Y+QPM  +  ++  HKY++D    D+  LE ++ + K+
Sbjct: 1135 KDLRTAYRSPNTEEIFNMLTKETPETFYIGKLIICNVTGIAHRRPQGESYDQA--IRNDETGLWQCPFCQQDNFPELSEVWNHFDSGSCPGQAIGVKTRLDNGVTGFIPTKFLSDKVVKRPEERVKVGMTVHCRIMKIDIEKFSADLTCRTSDLMDRNNEWKLPKDTYYDFDAEAADHKQEEDMK--RKQQRTTYIKRVIAHPSFHNINFKQAEKMMETMDQGDVIIRPSSKGENHLTVTWKVSDGIYQHVDVREEGKENAFSLGATLWINSEEFEDLDEIVARYVQPMASFARDLLNHKYYQDCSGGDRKKLEELLIKTKK 1452
[Close]
BLAST of Transcription elongation factor spt6 vs. Ensembl Human
Match: SUPT6H (SPT6 homolog, histone chaperone and transcription elongation factor [Source:HGNC Symbol;Acc:HGNC:11470])

HSP 1 Score: 225.713 bits (574), Expect = 8.999e-66
Identity = 118/322 (36.65%), Postives = 187/322 (58.07%), Query Frame = 1 
Query:    1 QDHRPRFISLTEQERFYFLTNENEETLKIGTVAEFRVINVVNRRNQKD-FDNANPKGNKDTGMFSCPICQEDNFHQLSEIWVHFDN-QCPGKAVGVNLLFENQIMTFVSIRNIADKFVRNVYDFVKVDQLVVGVVTNISYSKMKLEASLKQSDIKKAFEREKGRRDPHYDEKAENDEKSRKTKHKPSKNNKPIATNTRVSFHPNFKNLNYEQFMKMSHTLRANDFIIRPSSKGPNRLSISWKLSSNLFRHIDVKEEEKKNEFTIGQVLFIDSERFEDLDDIIANYLQPMIGYVDEIFTHKYFKDIRAEDKVTLERMIFEDKR 960
            +D R  + S   +E F  LT E  ET  IG +    V  + +RR Q + +D A    N +TG++ CP CQ+DNF +LSE+W HFD+  CPG+A+GV    +N +  F+  + ++DK V+   + VKV   V   +  I   K   + + + SD+       K  +D +YD  AE  +  ++   K  +  +      RV  HP+F N+N++Q  KM  T+   D IIRPSSKG N L+++WK+S  +++H+DV+EE K+N F++G  L+I+SE FEDLD+I+A Y+QPM  +  ++  HKY++D    D+  LE ++ + K+
Sbjct: 1135 KDLRTAYRSPNTEEIFNMLTKETPETFYIGKLIICNVTGIAHRRPQGESYDQA--IRNDETGLWQCPFCQQDNFPELSEVWNHFDSGSCPGQAIGVKTRLDNGVTGFIPTKFLSDKVVKRPEERVKVGMTVHCRIMKIDIEKFSADLTCRTSDLMDRNNEWKLPKDTYYDFDAEAADHKQEEDMK--RKQQRTTYIKRVIAHPSFHNINFKQAEKMMETMDQGDVIIRPSSKGENHLTVTWKVSDGIYQHVDVREEGKENAFSLGATLWINSEEFEDLDEIVARYVQPMASFARDLLNHKYYQDCSGGDRKKLEELLIKTKK 1452
[Close]
BLAST of Transcription elongation factor spt6 vs. Ensembl Celegans
Match: emb-5 (Suppressor of Ty 6 homolog [Source:UniProtKB/Swiss-Prot;Acc:P34703])

HSP 1 Score: 142.895 bits (359), Expect = 1.319e-37
Identity = 101/317 (31.86%), Postives = 158/317 (49.84%), Query Frame = 1 
Query:   40 ERFYFLTNENEETLKIGTVAEFRVINVVNRRNQKDFDNANPKGNKDTGMFSCPICQEDNFHQLSEIWVHF-----DNQCPGKAVGVNLLFENQIMTFVSIRNIADKFVRNVYDFVKVDQLVVGVVTNISYSKMKLEASLKQSDIKKAFEREKGRRDPHYDE-KAENDEKSRKTKHKPSKNNKPIATNTRVS---FHPNFKNLNYEQFMKMSHTLRANDFIIRPSSKGPNRLSISWKLSSNLFRHIDVKEEEKKNEFTIGQVLFIDSERFEDLDDIIANYLQPMIGYVDEIFTHKY-FKDIRAEDKVTLERMIFEDKR 960
            E  Y L   + + ++ G      V +V  R+  KD  ++      + G+F+CP C+         I  H         CPG  VG+ + F+N +  F   +NI+   V N    VK++Q     V  +   +  L  S K SD+K   E +  +RD ++DE + + D +  K++ K     K    NTRV     HPNF N++YE   KM   +  ++ IIRPS+   + LS++WK+   ++ +  VKE  K   F+IG+ L +  E FEDLD++IA ++QPMI    EI THKY F +   E+   +E+ + E KR
Sbjct: 1113 ELLYDLLARSGKEIREGAKVLGTVQSVQYRKVDKDAADSMLPDVGEDGLFTCPCCKSFTSSAPGGIQEHMLGDSRQGGCPGTPVGIRVRFDNGMTGFCPNKNISSSHVDNPLTRVKINQPYYFKVLKLDKERFSLFLSCKSSDLK---EDDLSQRDQYWDEHQYQADLELMKSESK-----KKTEANTRVKRVIAHPNFHNVSYEAATKMLDEMDWSECIIRPSANKDSGLSVTWKICDRVYHNFFVKESAKDQVFSIGRQLSVGGEDFEDLDELIARFVQPMIQISHEITTHKYFFPNGTCEETEAVEQFVREKKR 1421
[Close]
BLAST of Transcription elongation factor spt6 vs. Ensembl Fly
Match: Spt6 (gene:FBgn0028982 transcript:FBtr0070896)

HSP 1 Score: 199.134 bits (505), Expect = 7.709e-57
Identity = 109/328 (33.23%), Postives = 184/328 (56.10%), Query Frame = 1 
Query:    1 QDHRPRFISLTEQERFYFLTNENEETLKIGTVAEFRVINVVNRRNQKD-FDNANPKGNKDTGMFSCPICQEDNFHQLSEIWVHFD-NQCPGKAVGVNLLFENQIMTFVSIRNIADKFVRNVYDFVKVDQLVVGVVTNISYSKMKLEASLKQSDIKKAFEREKGRRDPHYDEKAENDEKSRKTKHKPSKNNKPIATNTRVSFHPNFKNLNYEQFMKMSHTLRANDFIIRPSSKGPNRLSISWKLSSNLFRHIDVKEEEKKNEFTIGQVLFIDSERFEDLDDIIANYLQPMIGYVDEIFTHKYFKDIRAE----DKVTLERMIFEDKRNN 966
            +D+R  +   + +E F  LT E  ++  +G      V     RR Q D  D+ANP        + CP C +D+F +LSE+W HFD N CPG+  GV +  EN +  F+ I+N++D+ VRN  + V+V Q++   +  I   +  +E S + +D+K      + RRD +YD   E ++ +RK     ++  K      RV  HP+F N +Y + + M       +  +RPSSK  + L+ +WK++ ++F+HIDV+EE K+N+F++G+ L+I +E FEDLD+IIA ++ PM     E+  +KY+K         ++  +E+++ E+K N+
Sbjct: 1137 KDYRTPYTKPSAEELFDMLTKETPDSFYVGKCVTAMVTGFTYRRPQGDQLDSANPVRLDSNESWQCPFCHKDDFPELSEVWNHFDANACPGQPSGVRVRLENGLPGFIHIKNLSDRQVRNPEERVRVSQMIHVRIIKIDIDRFSVECSSRTADLKDVNNEWRPRRDNYYDYVTE-EQDNRKVSDAKARALKRKIYARRVIAHPSFFNKSYAEVVAMLAEADQGEVALRPSSKSKDHLTATWKVADDIFQHIDVREEGKENDFSLGRSLWIGTEEFEDLDEIIARHIMPMALAARELIQYKYYKPNMVTGDENERDVMEKLLREEKAND 1463
[Close]
BLAST of Transcription elongation factor spt6 vs. Ensembl Fly
Match: Spt6 (gene:FBgn0028982 transcript:FBtr0340027)

HSP 1 Score: 199.134 bits (505), Expect = 7.709e-57
Identity = 109/328 (33.23%), Postives = 184/328 (56.10%), Query Frame = 1 
Query:    1 QDHRPRFISLTEQERFYFLTNENEETLKIGTVAEFRVINVVNRRNQKD-FDNANPKGNKDTGMFSCPICQEDNFHQLSEIWVHFD-NQCPGKAVGVNLLFENQIMTFVSIRNIADKFVRNVYDFVKVDQLVVGVVTNISYSKMKLEASLKQSDIKKAFEREKGRRDPHYDEKAENDEKSRKTKHKPSKNNKPIATNTRVSFHPNFKNLNYEQFMKMSHTLRANDFIIRPSSKGPNRLSISWKLSSNLFRHIDVKEEEKKNEFTIGQVLFIDSERFEDLDDIIANYLQPMIGYVDEIFTHKYFKDIRAE----DKVTLERMIFEDKRNN 966
            +D+R  +   + +E F  LT E  ++  +G      V     RR Q D  D+ANP        + CP C +D+F +LSE+W HFD N CPG+  GV +  EN +  F+ I+N++D+ VRN  + V+V Q++   +  I   +  +E S + +D+K      + RRD +YD   E ++ +RK     ++  K      RV  HP+F N +Y + + M       +  +RPSSK  + L+ +WK++ ++F+HIDV+EE K+N+F++G+ L+I +E FEDLD+IIA ++ PM     E+  +KY+K         ++  +E+++ E+K N+
Sbjct: 1137 KDYRTPYTKPSAEELFDMLTKETPDSFYVGKCVTAMVTGFTYRRPQGDQLDSANPVRLDSNESWQCPFCHKDDFPELSEVWNHFDANACPGQPSGVRVRLENGLPGFIHIKNLSDRQVRNPEERVRVSQMIHVRIIKIDIDRFSVECSSRTADLKDVNNEWRPRRDNYYDYVTE-EQDNRKVSDAKARALKRKIYARRVIAHPSFFNKSYAEVVAMLAEADQGEVALRPSSKSKDHLTATWKVADDIFQHIDVREEGKENDFSLGRSLWIGTEEFEDLDEIIARHIMPMALAARELIQYKYYKPNMVTGDENERDVMEKLLREEKAND 1463
[Close]
BLAST of Transcription elongation factor spt6 vs. Ensembl Zebrafish
Match: supt6h (SPT6 homolog, histone chaperone and transcription elongation factor [Source:NCBI gene;Acc:337866])

HSP 1 Score: 219.935 bits (559), Expect = 6.620e-64
Identity = 114/322 (35.40%), Postives = 187/322 (58.07%), Query Frame = 1 
Query:    1 QDHRPRFISLTEQERFYFLTNENEETLKIGTVAEFRVINVVNRRNQKD-FDNANPKGNKDTGMFSCPICQEDNFHQLSEIWVHFDN-QCPGKAVGVNLLFENQIMTFVSIRNIADKFVRNVYDFVKVDQLVVGVVTNISYSKMKLEASLKQSDIKKAFEREKGRRDPHYDEKAENDEKSRKTKHKPSKNNKPIATNTRVSFHPNFKNLNYEQFMKMSHTLRANDFIIRPSSKGPNRLSISWKLSSNLFRHIDVKEEEKKNEFTIGQVLFIDSERFEDLDDIIANYLQPMIGYVDEIFTHKYFKDIRAEDKVTLERMIFEDKR 960
            +D R  +     +E F  LT E  ET  IG +    V N+ +RR Q + +D A    N +TG++ CP CQ+DNF +LSE+W HFD+  CPG+A+GV    +N +M F+  + ++DK V++  + VK    V   +  I   K  ++ + + SD+       K  +D +YD  AE D+  ++ + K  +         RV  HP+F N+N++Q  KM  ++   D +IRPSSKG N L+++WK++  +++H+DV+EE K+N F++G  L+I++E FEDLD+I A Y+QPM  +  ++  HKYF +    D+  +E ++   K+
Sbjct: 1126 KDLRAPYRPPNTEEVFNMLTKETPETFYIGKLITCVVTNIAHRRPQGESYDQA--IRNDETGLWQCPFCQQDNFPELSEVWNHFDSGSCPGQAIGVRTRLDNAVMGFIPTKFLSDKVVKHPEERVKPGMTVHCRIMKIDIEKFNVDLTCRTSDLSDKNNEWKLPKDTYYDFDAETDDVKQEEEQKKKQQR--TTYIKRVIAHPSFHNINFKQAEKMMESMDQGDVVIRPSSKGENHLTVTWKVADGIYQHVDVREEGKENAFSLGHTLWINTEEFEDLDEITARYVQPMAAFARDLLGHKYFHECNGGDRKKMEELLVRTKK 1443
[Close]
BLAST of Transcription elongation factor spt6 vs. Ensembl Xenopus
Match: SUPT6H (SPT6 homolog, histone chaperone [Source:NCBI gene;Acc:780122])

HSP 1 Score: 223.402 bits (568), Expect = 4.878e-65
Identity = 118/322 (36.65%), Postives = 189/322 (58.70%), Query Frame = 1 
Query:    1 QDHRPRFISLTEQERFYFLTNENEETLKIGTVAEFRVINVVNRRNQKD-FDNANPKGNKDTGMFSCPICQEDNFHQLSEIWVHFDN-QCPGKAVGVNLLFENQIMTFVSIRNIADKFVRNVYDFVKVDQLVVGVVTNISYSKMKLEASLKQSDIKKAFEREKGRRDPHYDEKAENDEKSRKTKHKPSKNNKPIATNTRVSFHPNFKNLNYEQFMKMSHTLRANDFIIRPSSKGPNRLSISWKLSSNLFRHIDVKEEEKKNEFTIGQVLFIDSERFEDLDDIIANYLQPMIGYVDEIFTHKYFKDIRAEDKVTLERMIFEDKR 960
            +D R  + S   +E F  LT E  ET  IG +    V  + +RR Q + +D A    N +TG++ CP CQ+DNF +LSE+W HFD+  CPG+A+GV    +N +  F+  + I+DK V+   + VKV   V   +  I+  K  ++ + + SD+       K  +D +YD   E+ +  ++ + K  K  +      RV  HP+F N+N++Q  KM  T+   D IIRPSSKG N L+++WK+   +++H+DV+EE K+N F++G  L+I++E FEDLD+IIA ++QPM  +  ++  HKYF+D    +K  LE ++ + K+
Sbjct:  947 KDLRTTYRSPNPEEVFNMLTRETPETFYIGKLITCNVTGIAHRRPQGETYDQA--IRNDETGLWQCPFCQQDNFPELSEVWNHFDSGSCPGQAIGVKTRLDNSVTGFIPTKFISDKAVKRPEERVKVGMTVHCRIMKINIEKFSVDLTCRTSDLMDKNNEWKLPKDTYYDFDTESADHKQEEEFK--KKQQRTTYIKRVIAHPSFHNINFKQAEKMMETMDQGDVIIRPSSKGENHLTVTWKVCEGIYQHVDVREEGKENAFSLGSTLWINNEEFEDLDEIIARFVQPMASFARDLINHKYFQDCNNGEKKKLEELLIKTKK 1264
[Close]
BLAST of Transcription elongation factor spt6 vs. Ensembl Xenopus
Match: SUPT6H (SPT6 homolog, histone chaperone [Source:NCBI gene;Acc:780122])

HSP 1 Score: 223.402 bits (568), Expect = 4.878e-65
Identity = 118/322 (36.65%), Postives = 189/322 (58.70%), Query Frame = 1 
Query:    1 QDHRPRFISLTEQERFYFLTNENEETLKIGTVAEFRVINVVNRRNQKD-FDNANPKGNKDTGMFSCPICQEDNFHQLSEIWVHFDN-QCPGKAVGVNLLFENQIMTFVSIRNIADKFVRNVYDFVKVDQLVVGVVTNISYSKMKLEASLKQSDIKKAFEREKGRRDPHYDEKAENDEKSRKTKHKPSKNNKPIATNTRVSFHPNFKNLNYEQFMKMSHTLRANDFIIRPSSKGPNRLSISWKLSSNLFRHIDVKEEEKKNEFTIGQVLFIDSERFEDLDDIIANYLQPMIGYVDEIFTHKYFKDIRAEDKVTLERMIFEDKR 960
            +D R  + S   +E F  LT E  ET  IG +    V  + +RR Q + +D A    N +TG++ CP CQ+DNF +LSE+W HFD+  CPG+A+GV    +N +  F+  + I+DK V+   + VKV   V   +  I+  K  ++ + + SD+       K  +D +YD   E+ +  ++ + K  K  +      RV  HP+F N+N++Q  KM  T+   D IIRPSSKG N L+++WK+   +++H+DV+EE K+N F++G  L+I++E FEDLD+IIA ++QPM  +  ++  HKYF+D    +K  LE ++ + K+
Sbjct: 1121 KDLRTTYRSPNPEEVFNMLTRETPETFYIGKLITCNVTGIAHRRPQGETYDQA--IRNDETGLWQCPFCQQDNFPELSEVWNHFDSGSCPGQAIGVKTRLDNSVTGFIPTKFISDKAVKRPEERVKVGMTVHCRIMKINIEKFSVDLTCRTSDLMDKNNEWKLPKDTYYDFDTESADHKQEEEFK--KKQQRTTYIKRVIAHPSFHNINFKQAEKMMETMDQGDVIIRPSSKGENHLTVTWKVCEGIYQHVDVREEGKENAFSLGSTLWINNEEFEDLDEIIARFVQPMASFARDLINHKYFQDCNNGEKKKLEELLIKTKK 1438
[Close]
BLAST of Transcription elongation factor spt6 vs. Ensembl Xenopus
Match: SUPT6H (SPT6 homolog, histone chaperone [Source:NCBI gene;Acc:780122])

HSP 1 Score: 223.402 bits (568), Expect = 5.478e-65
Identity = 118/322 (36.65%), Postives = 189/322 (58.70%), Query Frame = 1 
Query:    1 QDHRPRFISLTEQERFYFLTNENEETLKIGTVAEFRVINVVNRRNQKD-FDNANPKGNKDTGMFSCPICQEDNFHQLSEIWVHFDN-QCPGKAVGVNLLFENQIMTFVSIRNIADKFVRNVYDFVKVDQLVVGVVTNISYSKMKLEASLKQSDIKKAFEREKGRRDPHYDEKAENDEKSRKTKHKPSKNNKPIATNTRVSFHPNFKNLNYEQFMKMSHTLRANDFIIRPSSKGPNRLSISWKLSSNLFRHIDVKEEEKKNEFTIGQVLFIDSERFEDLDDIIANYLQPMIGYVDEIFTHKYFKDIRAEDKVTLERMIFEDKR 960
            +D R  + S   +E F  LT E  ET  IG +    V  + +RR Q + +D A    N +TG++ CP CQ+DNF +LSE+W HFD+  CPG+A+GV    +N +  F+  + I+DK V+   + VKV   V   +  I+  K  ++ + + SD+       K  +D +YD   E+ +  ++ + K  K  +      RV  HP+F N+N++Q  KM  T+   D IIRPSSKG N L+++WK+   +++H+DV+EE K+N F++G  L+I++E FEDLD+IIA ++QPM  +  ++  HKYF+D    +K  LE ++ + K+
Sbjct: 1128 KDLRTTYRSPNPEEVFNMLTRETPETFYIGKLITCNVTGIAHRRPQGETYDQA--IRNDETGLWQCPFCQQDNFPELSEVWNHFDSGSCPGQAIGVKTRLDNSVTGFIPTKFISDKAVKRPEERVKVGMTVHCRIMKINIEKFSVDLTCRTSDLMDKNNEWKLPKDTYYDFDTESADHKQEEEFK--KKQQRTTYIKRVIAHPSFHNINFKQAEKMMETMDQGDVIIRPSSKGENHLTVTWKVCEGIYQHVDVREEGKENAFSLGSTLWINNEEFEDLDEIIARFVQPMASFARDLINHKYFQDCNNGEKKKLEELLIKTKK 1445
[Close]
BLAST of Transcription elongation factor spt6 vs. Ensembl Xenopus
Match: SUPT6H (SPT6 homolog, histone chaperone [Source:NCBI gene;Acc:780122])

HSP 1 Score: 223.016 bits (567), Expect = 6.119e-65
Identity = 118/322 (36.65%), Postives = 189/322 (58.70%), Query Frame = 1 
Query:    1 QDHRPRFISLTEQERFYFLTNENEETLKIGTVAEFRVINVVNRRNQKD-FDNANPKGNKDTGMFSCPICQEDNFHQLSEIWVHFDN-QCPGKAVGVNLLFENQIMTFVSIRNIADKFVRNVYDFVKVDQLVVGVVTNISYSKMKLEASLKQSDIKKAFEREKGRRDPHYDEKAENDEKSRKTKHKPSKNNKPIATNTRVSFHPNFKNLNYEQFMKMSHTLRANDFIIRPSSKGPNRLSISWKLSSNLFRHIDVKEEEKKNEFTIGQVLFIDSERFEDLDDIIANYLQPMIGYVDEIFTHKYFKDIRAEDKVTLERMIFEDKR 960
            +D R  + S   +E F  LT E  ET  IG +    V  + +RR Q + +D A    N +TG++ CP CQ+DNF +LSE+W HFD+  CPG+A+GV    +N +  F+  + I+DK V+   + VKV   V   +  I+  K  ++ + + SD+       K  +D +YD   E+ +  ++ + K  K  +      RV  HP+F N+N++Q  KM  T+   D IIRPSSKG N L+++WK+   +++H+DV+EE K+N F++G  L+I++E FEDLD+IIA ++QPM  +  ++  HKYF+D    +K  LE ++ + K+
Sbjct: 1080 KDLRTTYRSPNPEEVFNMLTRETPETFYIGKLITCNVTGIAHRRPQGETYDQA--IRNDETGLWQCPFCQQDNFPELSEVWNHFDSGSCPGQAIGVKTRLDNSVTGFIPTKFISDKAVKRPEERVKVGMTVHCRIMKINIEKFSVDLTCRTSDLMDKNNEWKLPKDTYYDFDTESADHKQEEEFK--KKQQRTTYIKRVIAHPSFHNINFKQAEKMMETMDQGDVIIRPSSKGENHLTVTWKVCEGIYQHVDVREEGKENAFSLGSTLWINNEEFEDLDEIIARFVQPMASFARDLINHKYFQDCNNGEKKKLEELLIKTKK 1397
[Close]
BLAST of Transcription elongation factor spt6 vs. Ensembl Xenopus
Match: SUPT6H (SPT6 homolog, histone chaperone [Source:NCBI gene;Acc:780122])

HSP 1 Score: 223.016 bits (567), Expect = 6.747e-65
Identity = 118/322 (36.65%), Postives = 189/322 (58.70%), Query Frame = 1 
Query:    1 QDHRPRFISLTEQERFYFLTNENEETLKIGTVAEFRVINVVNRRNQKD-FDNANPKGNKDTGMFSCPICQEDNFHQLSEIWVHFDN-QCPGKAVGVNLLFENQIMTFVSIRNIADKFVRNVYDFVKVDQLVVGVVTNISYSKMKLEASLKQSDIKKAFEREKGRRDPHYDEKAENDEKSRKTKHKPSKNNKPIATNTRVSFHPNFKNLNYEQFMKMSHTLRANDFIIRPSSKGPNRLSISWKLSSNLFRHIDVKEEEKKNEFTIGQVLFIDSERFEDLDDIIANYLQPMIGYVDEIFTHKYFKDIRAEDKVTLERMIFEDKR 960
            +D R  + S   +E F  LT E  ET  IG +    V  + +RR Q + +D A    N +TG++ CP CQ+DNF +LSE+W HFD+  CPG+A+GV    +N +  F+  + I+DK V+   + VKV   V   +  I+  K  ++ + + SD+       K  +D +YD   E+ +  ++ + K  K  +      RV  HP+F N+N++Q  KM  T+   D IIRPSSKG N L+++WK+   +++H+DV+EE K+N F++G  L+I++E FEDLD+IIA ++QPM  +  ++  HKYF+D    +K  LE ++ + K+
Sbjct: 1095 KDLRTTYRSPNPEEVFNMLTRETPETFYIGKLITCNVTGIAHRRPQGETYDQA--IRNDETGLWQCPFCQQDNFPELSEVWNHFDSGSCPGQAIGVKTRLDNSVTGFIPTKFISDKAVKRPEERVKVGMTVHCRIMKINIEKFSVDLTCRTSDLMDKNNEWKLPKDTYYDFDTESADHKQEEEFK--KKQQRTTYIKRVIAHPSFHNINFKQAEKMMETMDQGDVIIRPSSKGENHLTVTWKVCEGIYQHVDVREEGKENAFSLGSTLWINNEEFEDLDEIIARFVQPMASFARDLINHKYFQDCNNGEKKKLEELLIKTKK 1412
[Close]
BLAST of Transcription elongation factor spt6 vs. Ensembl Mouse
Match: Supt6 (SPT6, histone chaperone and transcription elongation factor [Source:MGI Symbol;Acc:MGI:107726])

HSP 1 Score: 226.483 bits (576), Expect = 3.436e-66
Identity = 118/322 (36.65%), Postives = 188/322 (58.39%), Query Frame = 1 
Query:    1 QDHRPRFISLTEQERFYFLTNENEETLKIGTVAEFRVINVVNRRNQKD-FDNANPKGNKDTGMFSCPICQEDNFHQLSEIWVHFDN-QCPGKAVGVNLLFENQIMTFVSIRNIADKFVRNVYDFVKVDQLVVGVVTNISYSKMKLEASLKQSDIKKAFEREKGRRDPHYDEKAENDEKSRKTKHKPSKNNKPIATNTRVSFHPNFKNLNYEQFMKMSHTLRANDFIIRPSSKGPNRLSISWKLSSNLFRHIDVKEEEKKNEFTIGQVLFIDSERFEDLDDIIANYLQPMIGYVDEIFTHKYFKDIRAEDKVTLERMIFEDKR 960
            +D R  + S   +E F  LT E  ET  IG +    V  + +RR Q + +D A    N +TG++ CP CQ+DNF +LSE+W HFD+  CPG+A+GV    +N +  F+  + ++DK V+   + VKV   V   +  I   K   + + + SD+       K  +D +YD  AE  +  ++   K  +  +      RV  HP+F N+N++Q  KM  T+   D IIRPSSKG N L+++WK+S+ +++H+DV+EE K+N F++G  L+I+SE FEDLD+I+A Y+QPM  +  ++  HKY++D    D+  LE ++ + K+
Sbjct: 1135 KDLRTAYRSPNTEEIFNMLTKETPETFYIGKLIICNVTGIAHRRPQGESYDQA--IRNDETGLWQCPFCQQDNFPELSEVWNHFDSGSCPGQAIGVKTRLDNGVTGFIPTKFLSDKVVKRPEERVKVGMTVHCRIMKIDIEKFSADLTCRTSDLMDRNNEWKLPKDTYYDFDAEAADHKQEEDMK--RKQQRTTYIKRVIAHPSFHNINFKQAEKMMETMDQGDVIIRPSSKGENHLTVTWKVSAGIYQHVDVREEGKENAFSLGATLWINSEEFEDLDEIVARYVQPMASFARDLLNHKYYQDCSGGDRKKLEELLIKTKK 1452
[Close]
BLAST of Transcription elongation factor spt6 vs. UniProt/SwissProt
Match: sp|Q62383|SPT6H_MOUSE (Transcription elongation factor SPT6 OS=Mus musculus OX=10090 GN=Supt6h PE=1 SV=2)

HSP 1 Score: 226.483 bits (576), Expect = 2.403e-65
Identity = 118/322 (36.65%), Postives = 188/322 (58.39%), Query Frame = 1 
Query:    1 QDHRPRFISLTEQERFYFLTNENEETLKIGTVAEFRVINVVNRRNQKD-FDNANPKGNKDTGMFSCPICQEDNFHQLSEIWVHFDN-QCPGKAVGVNLLFENQIMTFVSIRNIADKFVRNVYDFVKVDQLVVGVVTNISYSKMKLEASLKQSDIKKAFEREKGRRDPHYDEKAENDEKSRKTKHKPSKNNKPIATNTRVSFHPNFKNLNYEQFMKMSHTLRANDFIIRPSSKGPNRLSISWKLSSNLFRHIDVKEEEKKNEFTIGQVLFIDSERFEDLDDIIANYLQPMIGYVDEIFTHKYFKDIRAEDKVTLERMIFEDKR 960
            +D R  + S   +E F  LT E  ET  IG +    V  + +RR Q + +D A    N +TG++ CP CQ+DNF +LSE+W HFD+  CPG+A+GV    +N +  F+  + ++DK V+   + VKV   V   +  I   K   + + + SD+       K  +D +YD  AE  +  ++   K  +  +      RV  HP+F N+N++Q  KM  T+   D IIRPSSKG N L+++WK+S+ +++H+DV+EE K+N F++G  L+I+SE FEDLD+I+A Y+QPM  +  ++  HKY++D    D+  LE ++ + K+
Sbjct: 1135 KDLRTAYRSPNTEEIFNMLTKETPETFYIGKLIICNVTGIAHRRPQGESYDQA--IRNDETGLWQCPFCQQDNFPELSEVWNHFDSGSCPGQAIGVKTRLDNGVTGFIPTKFLSDKVVKRPEERVKVGMTVHCRIMKIDIEKFSADLTCRTSDLMDRNNEWKLPKDTYYDFDAEAADHKQEEDMK--RKQQRTTYIKRVIAHPSFHNINFKQAEKMMETMDQGDVIIRPSSKGENHLTVTWKVSAGIYQHVDVREEGKENAFSLGATLWINSEEFEDLDEIVARYVQPMASFARDLLNHKYYQDCSGGDRKKLEELLIKTKK 1452
[Close]
BLAST of Transcription elongation factor spt6 vs. UniProt/SwissProt
Match: sp|Q7KZ85|SPT6H_HUMAN (Transcription elongation factor SPT6 OS=Homo sapiens OX=9606 GN=SUPT6H PE=1 SV=2)

HSP 1 Score: 225.713 bits (574), Expect = 4.322e-65
Identity = 118/322 (36.65%), Postives = 187/322 (58.07%), Query Frame = 1 
Query:    1 QDHRPRFISLTEQERFYFLTNENEETLKIGTVAEFRVINVVNRRNQKD-FDNANPKGNKDTGMFSCPICQEDNFHQLSEIWVHFDN-QCPGKAVGVNLLFENQIMTFVSIRNIADKFVRNVYDFVKVDQLVVGVVTNISYSKMKLEASLKQSDIKKAFEREKGRRDPHYDEKAENDEKSRKTKHKPSKNNKPIATNTRVSFHPNFKNLNYEQFMKMSHTLRANDFIIRPSSKGPNRLSISWKLSSNLFRHIDVKEEEKKNEFTIGQVLFIDSERFEDLDDIIANYLQPMIGYVDEIFTHKYFKDIRAEDKVTLERMIFEDKR 960
            +D R  + S   +E F  LT E  ET  IG +    V  + +RR Q + +D A    N +TG++ CP CQ+DNF +LSE+W HFD+  CPG+A+GV    +N +  F+  + ++DK V+   + VKV   V   +  I   K   + + + SD+       K  +D +YD  AE  +  ++   K  +  +      RV  HP+F N+N++Q  KM  T+   D IIRPSSKG N L+++WK+S  +++H+DV+EE K+N F++G  L+I+SE FEDLD+I+A Y+QPM  +  ++  HKY++D    D+  LE ++ + K+
Sbjct: 1135 KDLRTAYRSPNTEEIFNMLTKETPETFYIGKLIICNVTGIAHRRPQGESYDQA--IRNDETGLWQCPFCQQDNFPELSEVWNHFDSGSCPGQAIGVKTRLDNGVTGFIPTKFLSDKVVKRPEERVKVGMTVHCRIMKIDIEKFSADLTCRTSDLMDRNNEWKLPKDTYYDFDAEAADHKQEEDMK--RKQQRTTYIKRVIAHPSFHNINFKQAEKMMETMDQGDVIIRPSSKGENHLTVTWKVSDGIYQHVDVREEGKENAFSLGATLWINSEEFEDLDEIVARYVQPMASFARDLLNHKYYQDCSGGDRKKLEELLIKTKK 1452
[Close]
BLAST of Transcription elongation factor spt6 vs. UniProt/SwissProt
Match: sp|Q8UVK2|SPT6H_DANRE (Transcription elongation factor SPT6 OS=Danio rerio OX=7955 GN=supt6h PE=1 SV=1)

HSP 1 Score: 219.935 bits (559), Expect = 4.997e-63
Identity = 114/322 (35.40%), Postives = 187/322 (58.07%), Query Frame = 1 
Query:    1 QDHRPRFISLTEQERFYFLTNENEETLKIGTVAEFRVINVVNRRNQKD-FDNANPKGNKDTGMFSCPICQEDNFHQLSEIWVHFDN-QCPGKAVGVNLLFENQIMTFVSIRNIADKFVRNVYDFVKVDQLVVGVVTNISYSKMKLEASLKQSDIKKAFEREKGRRDPHYDEKAENDEKSRKTKHKPSKNNKPIATNTRVSFHPNFKNLNYEQFMKMSHTLRANDFIIRPSSKGPNRLSISWKLSSNLFRHIDVKEEEKKNEFTIGQVLFIDSERFEDLDDIIANYLQPMIGYVDEIFTHKYFKDIRAEDKVTLERMIFEDKR 960
            +D R  +     +E F  LT E  ET  IG +    V N+ +RR Q + +D A    N +TG++ CP CQ+DNF +LSE+W HFD+  CPG+A+GV    +N +M F+  + ++DK V++  + VK    V   +  I   K  ++ + + SD+       K  +D +YD  AE D+  ++ + K  +         RV  HP+F N+N++Q  KM  ++   D +IRPSSKG N L+++WK++  +++H+DV+EE K+N F++G  L+I++E FEDLD+I A Y+QPM  +  ++  HKYF +    D+  +E ++   K+
Sbjct: 1126 KDLRAPYRPPNTEEVFNMLTKETPETFYIGKLITCVVTNIAHRRPQGESYDQA--IRNDETGLWQCPFCQQDNFPELSEVWNHFDSGSCPGQAIGVRTRLDNAVMGFIPTKFLSDKVVKHPEERVKPGMTVHCRIMKIDIEKFNVDLTCRTSDLSDKNNEWKLPKDTYYDFDAETDDVKQEEEQKKKQQR--TTYIKRVIAHPSFHNINFKQAEKMMESMDQGDVVIRPSSKGENHLTVTWKVADGIYQHVDVREEGKENAFSLGHTLWINTEEFEDLDEITARYVQPMAAFARDLLGHKYFHECNGGDRKKMEELLVRTKK 1443
[Close]
BLAST of Transcription elongation factor spt6 vs. UniProt/SwissProt
Match: sp|Q9W420|SPT6H_DROME (Transcription elongation factor SPT6 OS=Drosophila melanogaster OX=7227 GN=Spt6 PE=1 SV=1)

HSP 1 Score: 199.134 bits (505), Expect = 7.728e-56
Identity = 109/328 (33.23%), Postives = 184/328 (56.10%), Query Frame = 1 
Query:    1 QDHRPRFISLTEQERFYFLTNENEETLKIGTVAEFRVINVVNRRNQKD-FDNANPKGNKDTGMFSCPICQEDNFHQLSEIWVHFD-NQCPGKAVGVNLLFENQIMTFVSIRNIADKFVRNVYDFVKVDQLVVGVVTNISYSKMKLEASLKQSDIKKAFEREKGRRDPHYDEKAENDEKSRKTKHKPSKNNKPIATNTRVSFHPNFKNLNYEQFMKMSHTLRANDFIIRPSSKGPNRLSISWKLSSNLFRHIDVKEEEKKNEFTIGQVLFIDSERFEDLDDIIANYLQPMIGYVDEIFTHKYFKDIRAE----DKVTLERMIFEDKRNN 966
            +D+R  +   + +E F  LT E  ++  +G      V     RR Q D  D+ANP        + CP C +D+F +LSE+W HFD N CPG+  GV +  EN +  F+ I+N++D+ VRN  + V+V Q++   +  I   +  +E S + +D+K      + RRD +YD   E ++ +RK     ++  K      RV  HP+F N +Y + + M       +  +RPSSK  + L+ +WK++ ++F+HIDV+EE K+N+F++G+ L+I +E FEDLD+IIA ++ PM     E+  +KY+K         ++  +E+++ E+K N+
Sbjct: 1137 KDYRTPYTKPSAEELFDMLTKETPDSFYVGKCVTAMVTGFTYRRPQGDQLDSANPVRLDSNESWQCPFCHKDDFPELSEVWNHFDANACPGQPSGVRVRLENGLPGFIHIKNLSDRQVRNPEERVRVSQMIHVRIIKIDIDRFSVECSSRTADLKDVNNEWRPRRDNYYDYVTE-EQDNRKVSDAKARALKRKIYARRVIAHPSFFNKSYAEVVAMLAEADQGEVALRPSSKSKDHLTATWKVADDIFQHIDVREEGKENDFSLGRSLWIGTEEFEDLDEIIARHIMPMALAARELIQYKYYKPNMVTGDENERDVMEKLLREEKAND 1463
[Close]
BLAST of Transcription elongation factor spt6 vs. UniProt/SwissProt
Match: sp|P34703|SPT6H_CAEEL (Suppressor of Ty 6 homolog OS=Caenorhabditis elegans OX=6239 GN=emb-5 PE=1 SV=1)

HSP 1 Score: 142.895 bits (359), Expect = 1.677e-36
Identity = 101/317 (31.86%), Postives = 158/317 (49.84%), Query Frame = 1 
Query:   40 ERFYFLTNENEETLKIGTVAEFRVINVVNRRNQKDFDNANPKGNKDTGMFSCPICQEDNFHQLSEIWVHF-----DNQCPGKAVGVNLLFENQIMTFVSIRNIADKFVRNVYDFVKVDQLVVGVVTNISYSKMKLEASLKQSDIKKAFEREKGRRDPHYDE-KAENDEKSRKTKHKPSKNNKPIATNTRVS---FHPNFKNLNYEQFMKMSHTLRANDFIIRPSSKGPNRLSISWKLSSNLFRHIDVKEEEKKNEFTIGQVLFIDSERFEDLDDIIANYLQPMIGYVDEIFTHKY-FKDIRAEDKVTLERMIFEDKR 960
            E  Y L   + + ++ G      V +V  R+  KD  ++      + G+F+CP C+         I  H         CPG  VG+ + F+N +  F   +NI+   V N    VK++Q     V  +   +  L  S K SD+K   E +  +RD ++DE + + D +  K++ K     K    NTRV     HPNF N++YE   KM   +  ++ IIRPS+   + LS++WK+   ++ +  VKE  K   F+IG+ L +  E FEDLD++IA ++QPMI    EI THKY F +   E+   +E+ + E KR
Sbjct: 1113 ELLYDLLARSGKEIREGAKVLGTVQSVQYRKVDKDAADSMLPDVGEDGLFTCPCCKSFTSSAPGGIQEHMLGDSRQGGCPGTPVGIRVRFDNGMTGFCPNKNISSSHVDNPLTRVKINQPYYFKVLKLDKERFSLFLSCKSSDLK---EDDLSQRDQYWDEHQYQADLELMKSESK-----KKTEANTRVKRVIAHPNFHNVSYEAATKMLDEMDWSECIIRPSANKDSGLSVTWKICDRVYHNFFVKESAKDQVFSIGRQLSVGGEDFEDLDELIARFVQPMIQISHEITTHKYFFPNGTCEETEAVEQFVREKKR 1421
[Close]
BLAST of Transcription elongation factor spt6 vs. TrEMBL
Match: T1DJP1 (Putative transcription elongation factor spt6 (Fragment) OS=Psorophora albipes OX=869069 PE=2 SV=1)

HSP 1 Score: 243.817 bits (621), Expect = 6.054e-69
Identity = 123/324 (37.96%), Postives = 197/324 (60.80%), Query Frame = 1 
Query:    1 QDHRPRFISLTEQERFYFLTNENEETLKIGTVAEFRVINVVNRRNQKD-FDNANPKGNKDTGMFSCPICQEDNFHQLSEIWVHFD-NQCPGKAVGVNLLFENQIMTFVSIRNIADKFVRNVYDFVKVDQLVVGVVTNISYSKMKLEASLKQSDIKKAFEREKGRRDPHYDEKAENDEKSRKTKHKPSKNNKPIATNTRVSFHPNFKNLNYEQFMKMSHTLRANDFIIRPSSKGPNRLSISWKLSSNLFRHIDVKEEEKKNEFTIGQVLFIDSERFEDLDDIIANYLQPMIGYVDEIFTHKYFKDIRAEDKVTLERMIFEDKRNN 966
            +D R  + S+T +E F +LT E  ETL +G +    V  + +R+ Q D  D ANP  N +TG++ CP C ++ F +LSE+W HFD  +CPG+A GV + F+N +  F+ I+NI+DK V+N  + V++ Q +   VT I   +  L+ S K SD+       + R+D  YD+ AE+ +  ++   K  K  +      RV  HP+F N++Y + +K+   L   D I+RPSSKG + L+ +WK++ ++++HID++EE K+N F++GQ L+I +E FEDLD+IIA Y+ PM  Y  ++  +KY+KD     K   E +I ++K+ N
Sbjct: 1137 KDLRTPYRSVTAEELFDYLTKETPETLYVGKMMLATVAGISHRKPQGDQLDQANPVRNDETGLWQCPFCMQNEFPELSEVWNHFDAGECPGQATGVRVRFDNGLSGFIHIKNISDKHVKNPEERVQIGQTIHVRVTKIDVERFSLDCSSKSSDLADKNNEWRPRKDQFYDQDAEDKDNKKEMDTKKQKQRQQYIK--RVIVHPSFHNISYAEALKLLDQLDQGDVIVRPSSKGADHLTATWKITKDIYQHIDIREEGKENVFSLGQSLWIGNEEFEDLDEIIARYINPMASYARDLLNYKYYKDTSGGMKDKAEEIIKDEKKKN 1458
[Close]
BLAST of Transcription elongation factor spt6 vs. TrEMBL
Match: T1E3R0 (Putative transcription elongation factor spt6 (Fragment) OS=Psorophora albipes OX=869069 PE=2 SV=1)

HSP 1 Score: 243.817 bits (621), Expect = 6.263e-69
Identity = 123/324 (37.96%), Postives = 197/324 (60.80%), Query Frame = 1 
Query:    1 QDHRPRFISLTEQERFYFLTNENEETLKIGTVAEFRVINVVNRRNQKD-FDNANPKGNKDTGMFSCPICQEDNFHQLSEIWVHFD-NQCPGKAVGVNLLFENQIMTFVSIRNIADKFVRNVYDFVKVDQLVVGVVTNISYSKMKLEASLKQSDIKKAFEREKGRRDPHYDEKAENDEKSRKTKHKPSKNNKPIATNTRVSFHPNFKNLNYEQFMKMSHTLRANDFIIRPSSKGPNRLSISWKLSSNLFRHIDVKEEEKKNEFTIGQVLFIDSERFEDLDDIIANYLQPMIGYVDEIFTHKYFKDIRAEDKVTLERMIFEDKRNN 966
            +D R  + S+T +E F +LT E  ETL +G +    V  + +R+ Q D  D ANP  N +TG++ CP C ++ F +LSE+W HFD  +CPG+A GV + F+N +  F+ I+NI+DK V+N  + V++ Q +   VT I   +  L+ S K SD+       + R+D  YD+ AE+ +  ++   K  K  +      RV  HP+F N++Y + +K+   L   D I+RPSSKG + L+ +WK++ ++++HID++EE K+N F++GQ L+I +E FEDLD+IIA Y+ PM  Y  ++  +KY+KD     K   E +I ++K+ N
Sbjct: 1089 KDLRTPYRSVTAEELFDYLTKETPETLYVGKMMLATVAGISHRKPQGDQLDQANPVRNDETGLWQCPFCMQNEFPELSEVWNHFDAGECPGQATGVRVRFDNGLSGFIHIKNISDKHVKNPEERVQIGQTIHVRVTKIDVERFSLDCSSKSSDLADKNNEWRPRKDQFYDQDAEDKDNKKEMDTKKQKQRQQYIK--RVIVHPSFHNISYAEALKLLDQLDQGDVIVRPSSKGADHLTATWKITKDIYQHIDIREEGKENVFSLGQSLWIGNEEFEDLDEIIARYINPMASYARDLLNYKYYKDTSGGMKDKAEEIIKDEKKKN 1410
[Close]
BLAST of Transcription elongation factor spt6 vs. TrEMBL
Match: A0A1S4FF27 (Transcription elongation factor spt6 OS=Aedes aegypti OX=7159 GN=5568538 PE=3 SV=1)

HSP 1 Score: 243.047 bits (619), Expect = 1.101e-68
Identity = 119/304 (39.14%), Postives = 191/304 (62.83%), Query Frame = 1 
Query:    1 QDHRPRFISLTEQERFYFLTNENEETLKIGTVAEFRVINVVNRRNQKD-FDNANPKGNKDTGMFSCPICQEDNFHQLSEIWVHFD-NQCPGKAVGVNLLFENQIMTFVSIRNIADKFVRNVYDFVKVDQLVVGVVTNISYSKMKLEASLKQSDIKKAFEREKGRRDPHYDEKAENDEKSRKTKHKPSKNNKPIATNTRVSFHPNFKNLNYEQFMKMSHTLRANDFIIRPSSKGPNRLSISWKLSSNLFRHIDVKEEEKKNEFTIGQVLFIDSERFEDLDDIIANYLQPMIGYVDEIFTHKYFKD 906
            +D R  + S T +E F +LT E  E+L +G +    V  + +R+ Q D  D ANP  N +TG++ CP C ++ F +LSE+W HFD  +CPG+A GV L F+N +  F+ I+NI+DK V+N  + V++ Q +   +T I   +  L+ S K SD+       + R+DP+YD++AE+ +  ++T  K  K  +      RV  HP+F N++Y + +K+   L   + I+RPSSKG + L+ +WK++ ++++HIDV+EE K+N F++GQ L+I +E FEDLD+IIA Y+ PM  Y  ++  +KY+KD
Sbjct: 1130 KDLRTPYRSCTAEELFDYLTKETPESLYVGKMMLATVAGISHRKPQGDQLDQANPVRNDETGLWQCPFCMQNEFPELSEVWNHFDAGECPGQATGVRLRFDNGLTGFIHIKNISDKHVKNPEERVQMGQTIHVRITKIDVERFTLDCSSKSSDLADKNNEWRPRKDPNYDQEAEDRDNKKETDTKKQKQRQQYIK--RVIVHPSFHNISYAEALKLLDQLDQGEVIVRPSSKGADHLTATWKVTKDIYQHIDVREEGKENVFSLGQSLWIGNEEFEDLDEIIARYINPMAAYARDLLNYKYYKD 1431
[Close]
BLAST of Transcription elongation factor spt6 vs. TrEMBL
Match: Q174B1 (Transcription elongation factor spt6 OS=Aedes aegypti OX=7159 GN=AAEL006956 PE=3 SV=1)

HSP 1 Score: 243.047 bits (619), Expect = 1.122e-68
Identity = 119/304 (39.14%), Postives = 191/304 (62.83%), Query Frame = 1 
Query:    1 QDHRPRFISLTEQERFYFLTNENEETLKIGTVAEFRVINVVNRRNQKD-FDNANPKGNKDTGMFSCPICQEDNFHQLSEIWVHFD-NQCPGKAVGVNLLFENQIMTFVSIRNIADKFVRNVYDFVKVDQLVVGVVTNISYSKMKLEASLKQSDIKKAFEREKGRRDPHYDEKAENDEKSRKTKHKPSKNNKPIATNTRVSFHPNFKNLNYEQFMKMSHTLRANDFIIRPSSKGPNRLSISWKLSSNLFRHIDVKEEEKKNEFTIGQVLFIDSERFEDLDDIIANYLQPMIGYVDEIFTHKYFKD 906
            +D R  + S T +E F +LT E  E+L +G +    V  + +R+ Q D  D ANP  N +TG++ CP C ++ F +LSE+W HFD  +CPG+A GV L F+N +  F+ I+NI+DK V+N  + V++ Q +   +T I   +  L+ S K SD+       + R+DP+YD++AE+ +  ++T  K  K  +      RV  HP+F N++Y + +K+   L   + I+RPSSKG + L+ +WK++ ++++HIDV+EE K+N F++GQ L+I +E FEDLD+IIA Y+ PM  Y  ++  +KY+KD
Sbjct: 1130 KDLRTPYRSCTAEELFDYLTKETPESLYVGKMMLATVAGISHRKPQGDQLDQANPVRNDETGLWQCPFCMQNEFPELSEVWNHFDAGECPGQATGVRLRFDNGLTGFIHIKNISDKHVKNPEERVQMGQTIHVRITKIDVERFTLDCSSKSSDLADKNNEWRPRKDPNYDQEAEDRDNKKETDTKKQKQRQQYIK--RVIVHPSFHNISYAEALKLLDQLDQGEVIVRPSSKGADHLTATWKVTKDIYQHIDVREEGKENVFSLGQSLWIGNEEFEDLDEIIARYINPMAAYARDLLNYKYYKD 1431
[Close]
BLAST of Transcription elongation factor spt6 vs. TrEMBL
Match: A0A419QG36 (Transcription elongation factor spt6 OS=Clonorchis sinensis OX=79923 GN=supt6h PE=3 SV=1)

HSP 1 Score: 239.965 bits (611), Expect = 1.495e-67
Identity = 121/326 (37.12%), Postives = 194/326 (59.51%), Query Frame = 1 
Query:    1 QDHRPRFISLTEQERFYFLTNENEETLKIGTVAEFRVINVVNRRNQKD-FDNANPKGNKDTGMFSCPICQEDNFHQLSEIWVHFDN-QCPGKAVGVNLLFENQIMTFVSIRNIADKFVRNVYDFVKVDQLVVGVVTNISYSKMKLEASLKQSDIKKAFEREKGRRDPHYDEKA-ENDEKSRKT-KHKPSKNNKPIATNTRVSFHPNFKNLNYEQFMKMSHTLRANDFIIRPSSKGPNRLSISWKLSSNLFRHIDVKEEEKKNEFTIGQVLFIDSERFEDLDDIIANYLQPMIGYVDEIFTHKYFKDIRAEDKVTLERMIFEDKRNN 966
            +D+R  + S   +  F  +T+E  ET  +G + E RV+ V  RR + +  DNANP  N+  G++ CP C++DNF  L+ +W HFDN +CPG+AVG+ +  +N I  F+ +R + D     +++  +   L+   V  I  +K  +E + KQSD++      + R DP YD +A E D  + +T K K  +N  P  +  RV FHP +KN++Y+Q + M   L     +IRPS +G + L++SWK+     +HIDV E+EK N F++G++L I  E FEDLD+I+A ++QPM   V +I T++Y++D R  D+  L  ++ ++K NN
Sbjct: 1114 RDYRAPYQSANPEMIFSMVTHETPETFHVGRLIECRVVAVATRRPRPEQLDNANPTKNETNGLWMCPFCRQDNFQFLNNVWSHFDNNECPGQAVGLRVQLDNGIAGFIPLR-LTDPPAEKLFERAQPGTLIRCRVMKIDITKFNVELTCKQSDLQDERHMWRPRPDPFYDYEADEQDVLAEETAKAKVKENATPYLS--RVIFHPYYKNISYDQLLAMEPELEPGSIVIRPSRRGADHLTVSWKVDDGTLQHIDVLEKEKTNSFSLGRLLIIGDEEFEDLDEIVARHVQPMASLVRDIMTYRYYRDSRGGDRAVLGALLLQEKSNN 1436
[Close]
BLAST of Transcription elongation factor spt6 vs. Ensembl Cavefish
Match: supt6h (SPT6 homolog, histone chaperone and transcription elongation factor [Source:NCBI gene;Acc:103045879])

HSP 1 Score: 227.639 bits (579), Expect = 1.053e-66
Identity = 116/322 (36.02%), Postives = 190/322 (59.01%), Query Frame = 1 
Query:    1 QDHRPRFISLTEQERFYFLTNENEETLKIGTVAEFRVINVVNRRNQKD-FDNANPKGNKDTGMFSCPICQEDNFHQLSEIWVHFDN-QCPGKAVGVNLLFENQIMTFVSIRNIADKFVRNVYDFVKVDQLVVGVVTNISYSKMKLEASLKQSDIKKAFEREKGRRDPHYDEKAENDEKSRKTKHKPSKNNKPIATNTRVSFHPNFKNLNYEQFMKMSHTLRANDFIIRPSSKGPNRLSISWKLSSNLFRHIDVKEEEKKNEFTIGQVLFIDSERFEDLDDIIANYLQPMIGYVDEIFTHKYFKDIRAEDKVTLERMIFEDKR 960
            +D R  +     +E F  LT E  ET  IG +    V  + +RR Q + +D A    N +TG++ CP CQ+DNF +LSE+W HFD+  CPG+A+GV    +N +M F+  + ++DK V++  + VKV   V   +  I   K  ++ + + SD+       K  +D +YD  AE D+  ++ + K  K  +      RV  HP+F N+N++Q  KM  T+   D +IRPSSKG N L+++WK++  +++H+DV+EE K+N F++G  L+I++E FEDLD+I A Y+QPM  +  ++ +HKYF++    D+  +E ++   K+
Sbjct: 1143 KDLRAPYRPPNTEEVFNLLTKETPETFYIGKLITSVVTGIAHRRPQGESYDQA--IRNDETGLWQCPFCQQDNFPELSEVWNHFDSGSCPGQAIGVRTRLDNAVMGFIPTKFLSDKVVKHPEERVKVGMTVHCRIMKIDIEKFNVDLTCRSSDLADKNNEWKLPKDTYYDFDAETDDVKQEEELK--KKQQRTTYIKRVIAHPSFHNINFKQAEKMMETMDQGDVVIRPSSKGENHLTVTWKVADGIYQHVDVREEGKENAFSLGHTLWINTEEFEDLDEITARYVQPMAAFARDLLSHKYFQECNGGDRKKMEELLVRCKK 1460
[Close]
BLAST of Transcription elongation factor spt6 vs. Ensembl Cavefish
Match: supt6h (SPT6 homolog, histone chaperone and transcription elongation factor [Source:NCBI gene;Acc:103045879])

HSP 1 Score: 227.254 bits (578), Expect = 1.220e-66
Identity = 116/322 (36.02%), Postives = 190/322 (59.01%), Query Frame = 1 
Query:    1 QDHRPRFISLTEQERFYFLTNENEETLKIGTVAEFRVINVVNRRNQKD-FDNANPKGNKDTGMFSCPICQEDNFHQLSEIWVHFDN-QCPGKAVGVNLLFENQIMTFVSIRNIADKFVRNVYDFVKVDQLVVGVVTNISYSKMKLEASLKQSDIKKAFEREKGRRDPHYDEKAENDEKSRKTKHKPSKNNKPIATNTRVSFHPNFKNLNYEQFMKMSHTLRANDFIIRPSSKGPNRLSISWKLSSNLFRHIDVKEEEKKNEFTIGQVLFIDSERFEDLDDIIANYLQPMIGYVDEIFTHKYFKDIRAEDKVTLERMIFEDKR 960
            +D R  +     +E F  LT E  ET  IG +    V  + +RR Q + +D A    N +TG++ CP CQ+DNF +LSE+W HFD+  CPG+A+GV    +N +M F+  + ++DK V++  + VKV   V   +  I   K  ++ + + SD+       K  +D +YD  AE D+  ++ + K  K  +      RV  HP+F N+N++Q  KM  T+   D +IRPSSKG N L+++WK++  +++H+DV+EE K+N F++G  L+I++E FEDLD+I A Y+QPM  +  ++ +HKYF++    D+  +E ++   K+
Sbjct: 1072 KDLRAPYRPPNTEEVFNLLTKETPETFYIGKLITSVVTGIAHRRPQGESYDQA--IRNDETGLWQCPFCQQDNFPELSEVWNHFDSGSCPGQAIGVRTRLDNAVMGFIPTKFLSDKVVKHPEERVKVGMTVHCRIMKIDIEKFNVDLTCRSSDLADKNNEWKLPKDTYYDFDAETDDVKQEEELK--KKQQRTTYIKRVIAHPSFHNINFKQAEKMMETMDQGDVVIRPSSKGENHLTVTWKVADGIYQHVDVREEGKENAFSLGHTLWINTEEFEDLDEITARYVQPMAAFARDLLSHKYFQECNGGDRKKMEELLVRCKK 1389
[Close]
BLAST of Transcription elongation factor spt6 vs. Ensembl Yeast
Match: SPT6 (Nucleosome remodeling protein; functions in various aspects of transcription, chromatin maintenance, and RNA processing; required for the maintenance of chromatin structure during transcription in order to inhibit transcription from promoters within the coding region; required for H3K36 trimethylation but not dimethylation by Set2p [Source:SGD;Acc:S000003348])

HSP 1 Score: 92.8189 bits (229), Expect = 2.664e-21
Identity = 60/204 (29.41%), Postives = 106/204 (51.96%), Query Frame = 1 
Query:  325 RNIADKFVRNVYDFVKVDQLVVGVVTNISYSKMKLEASLKQSDIKKAFEREKGRRDPH-YD--EKAENDEKSRKTKHKPSKNNKPIATNTRVSFHPNFKNLNYEQFMKMSHTLRANDFIIRPSSKGPNRLSISWKLSSNLFRHIDVKEEEKKNEFTIGQVLFIDSERFEDLDDIIANYLQPMIGYVDEIFTHKYFKDIRAEDKV 927
            R+   +  R   +  ++ +     V  I Y+ +  E SL   D+K+ +      +DP  +D  ++ E+ E+ RK     ++  +      RV  HP +   N  Q      +    +F+IR SS+G + L I+WKL  +LF+HID++E EK+N   +G+VL +D++++ DLD II  YLQ  +  ++E+ + + FK    +D V
Sbjct: 1166 RHAGAQLRRPANEIYEIGKTYPAKVIYIDYANITAEVSLLDHDVKQQYVPISYSKDPSIWDLKQELEDAEEERKLMMAEARAKR----THRVINHPYYFPFNGRQAEDYLRSKERGEFVIRQSSRGDDHLVITWKLDKDLFQHIDIQELEKENPLALGKVLIVDNQKYNDLDQIIVEYLQNKVRLLNEMTSSEKFKSGTKKDVV 1365
[Close]
BLAST of Transcription elongation factor spt6 vs. Ensembl Nematostella
Match: EDO33602 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SRR7])

HSP 1 Score: 216.853 bits (551), Expect = 1.985e-63
Identity = 114/322 (35.40%), Postives = 189/322 (58.70%), Query Frame = 1 
Query:    4 DHRPRFISLTEQERFYFLTNENEETLKIGTVAEFRVINVVNRRNQKDF-DNANPKGNKDTGMFSCPICQEDNFHQLSEIWVHFDN-QCPGKAVGVNLLFENQIMTFVSIRNIADKFVRNVYDFVKVDQLVVGVVTNISYSKMKLEASLKQSDIKKAFEREKGRRDPHYDEKAEN-DEKSRKTKHKPSKNNKPIATNTRVSFHPNFKNLNYEQFMKMSHTLRANDFIIRPSSKGPNRLSISWKLSSNLFRHIDVKEEEKKNEFTIGQVLFIDSERFEDLDDIIANYLQPMIGYVDEIFTHKYFKDIRAEDKVTLERMIFEDKR 960
            + R  F  L+ ++RF  LT E  ETL +G +    V     R+   D  D ANP+  +DTG++ CP C ++++ +LSE+W H DN  CPG A GV +  EN I  F+  + I+DK +++  + VK    +   VT ++  + +++ S + SD+    ++     D +YD+ AE  D+K  +T  K  K N+P     RV  HP F+N+++++  ++   L   + I+RPSSKG + L+++WK+   +++HID++EE K+N F++G  L+ID+E FEDLD+IIA ++QPM     EI  HKY++      K  LE ++  +K+
Sbjct:  982 ERRVPFRPLSVEDRFKVLTGETSETLYVGKMVMCTVTGFAFRKPSHDMVDQANPEKVEDTGLWQCPFCLKNDYPELSEVWTHLDNGSCPGNATGVRVRMENGISGFIPTKMISDKHIKSPQERVKPGMTLHCRVTRMNMERFQVDLSCRSSDLADKDKKFSLPFDLYYDKDAEEKDKKEDETAKK--KANRPKYIK-RVIVHPAFRNISFKEAERILSELDQGESIVRPSSKGSDHLTVTWKVDQGIYQHIDIREEGKENAFSLGHSLWIDTEEFEDLDEIIARHIQPMAALAREILNHKYYRAADGGSKAKLEELLVLEKK 1300
[Close]
BLAST of Transcription elongation factor spt6 vs. Ensembl Medaka
Match: supt6h (SPT6 homolog, histone chaperone and transcription elongation factor [Source:NCBI gene;Acc:101164914])

HSP 1 Score: 222.631 bits (566), Expect = 4.847e-65
Identity = 115/310 (37.10%), Postives = 180/310 (58.06%), Query Frame = 1 
Query:   37 QERFYFLTNENEETLKIGTVAEFRVINVVNRRNQKD-FDNANPKGNKDTGMFSCPICQEDNFHQLSEIWVHFDN-QCPGKAVGVNLLFENQIMTFVSIRNIADKFVRNVYDFVKVDQLVVGVVTNISYSKMKLEASLKQSDIKKAFEREKGRRDPHYDEKAENDEKSRKTKHKPSKNNKPIATNTRVSFHPNFKNLNYEQFMKMSHTLRANDFIIRPSSKGPNRLSISWKLSSNLFRHIDVKEEEKKNEFTIGQVLFIDSERFEDLDDIIANYLQPMIGYVDEIFTHKYFKDIRAEDKVTLERMIFEDKR 960
            +E F  LT E  ET  IG +    V  + +RR Q + +D A    N  TG++ CP CQ+DNF +LSE+W HFD+  CPG+A+GV    +N +  F+  + ++DK V++  + VKV   V   +  I   K  ++ + + SD+       K  +D +YD   E +++    + K  +   P     RV  HPNF N+++ Q  KM  TL   D IIRPSSKG N L+++WK++  +++H+DV+EE K+N F++G  L+I++E FEDLD+IIA Y+QPM  +  ++  HKYF+D     +  +E  + + KR
Sbjct: 1111 EEVFNMLTKETPETFYIGKLITSIVTGIAHRRPQGESYDQA--IRNDATGLWQCPFCQQDNFPELSEVWNHFDSGSCPGQAIGVRSRLDNGVQGFIPTKFLSDKVVKHPEERVKVGMTVHCRIMKIDIEKFSVDLTCRTSDLMDKNNEWKLPKDTYYDFDTEAEDQKHDEELKKKQQRTPYIK--RVIAHPNFHNISFNQAEKMMETLDQGDLIIRPSSKGENHLTVTWKVADGIYQHVDVREEGKENAFSLGHTLWINNEEFEDLDEIIARYIQPMASFARDLLGHKYFQDCNGGSREKMEEALIKTKR 1416
[Close]
BLAST of Transcription elongation factor spt6 vs. Ensembl Medaka
Match: supt6h (SPT6 homolog, histone chaperone and transcription elongation factor [Source:NCBI gene;Acc:101164914])

HSP 1 Score: 222.631 bits (566), Expect = 5.247e-65
Identity = 115/310 (37.10%), Postives = 180/310 (58.06%), Query Frame = 1 
Query:   37 QERFYFLTNENEETLKIGTVAEFRVINVVNRRNQKD-FDNANPKGNKDTGMFSCPICQEDNFHQLSEIWVHFDN-QCPGKAVGVNLLFENQIMTFVSIRNIADKFVRNVYDFVKVDQLVVGVVTNISYSKMKLEASLKQSDIKKAFEREKGRRDPHYDEKAENDEKSRKTKHKPSKNNKPIATNTRVSFHPNFKNLNYEQFMKMSHTLRANDFIIRPSSKGPNRLSISWKLSSNLFRHIDVKEEEKKNEFTIGQVLFIDSERFEDLDDIIANYLQPMIGYVDEIFTHKYFKDIRAEDKVTLERMIFEDKR 960
            +E F  LT E  ET  IG +    V  + +RR Q + +D A    N  TG++ CP CQ+DNF +LSE+W HFD+  CPG+A+GV    +N +  F+  + ++DK V++  + VKV   V   +  I   K  ++ + + SD+       K  +D +YD   E +++    + K  +   P     RV  HPNF N+++ Q  KM  TL   D IIRPSSKG N L+++WK++  +++H+DV+EE K+N F++G  L+I++E FEDLD+IIA Y+QPM  +  ++  HKYF+D     +  +E  + + KR
Sbjct: 1134 EEVFNMLTKETPETFYIGKLITSIVTGIAHRRPQGESYDQA--IRNDATGLWQCPFCQQDNFPELSEVWNHFDSGSCPGQAIGVRSRLDNGVQGFIPTKFLSDKVVKHPEERVKVGMTVHCRIMKIDIEKFSVDLTCRTSDLMDKNNEWKLPKDTYYDFDTEAEDQKHDEELKKKQQRTPYIK--RVIAHPNFHNISFNQAEKMMETLDQGDLIIRPSSKGENHLTVTWKVADGIYQHVDVREEGKENAFSLGHTLWINNEEFEDLDEIIARYIQPMASFARDLLGHKYFQDCNGGSREKMEEALIKTKR 1439
[Close]
BLAST of Transcription elongation factor spt6 vs. Ensembl Medaka
Match: supt6h (SPT6 homolog, histone chaperone and transcription elongation factor [Source:NCBI gene;Acc:101164914])

HSP 1 Score: 222.631 bits (566), Expect = 5.293e-65
Identity = 115/310 (37.10%), Postives = 180/310 (58.06%), Query Frame = 1 
Query:   37 QERFYFLTNENEETLKIGTVAEFRVINVVNRRNQKD-FDNANPKGNKDTGMFSCPICQEDNFHQLSEIWVHFDN-QCPGKAVGVNLLFENQIMTFVSIRNIADKFVRNVYDFVKVDQLVVGVVTNISYSKMKLEASLKQSDIKKAFEREKGRRDPHYDEKAENDEKSRKTKHKPSKNNKPIATNTRVSFHPNFKNLNYEQFMKMSHTLRANDFIIRPSSKGPNRLSISWKLSSNLFRHIDVKEEEKKNEFTIGQVLFIDSERFEDLDDIIANYLQPMIGYVDEIFTHKYFKDIRAEDKVTLERMIFEDKR 960
            +E F  LT E  ET  IG +    V  + +RR Q + +D A    N  TG++ CP CQ+DNF +LSE+W HFD+  CPG+A+GV    +N +  F+  + ++DK V++  + VKV   V   +  I   K  ++ + + SD+       K  +D +YD   E +++    + K  +   P     RV  HPNF N+++ Q  KM  TL   D IIRPSSKG N L+++WK++  +++H+DV+EE K+N F++G  L+I++E FEDLD+IIA Y+QPM  +  ++  HKYF+D     +  +E  + + KR
Sbjct: 1070 EEVFNMLTKETPETFYIGKLITSIVTGIAHRRPQGESYDQA--IRNDATGLWQCPFCQQDNFPELSEVWNHFDSGSCPGQAIGVRSRLDNGVQGFIPTKFLSDKVVKHPEERVKVGMTVHCRIMKIDIEKFSVDLTCRTSDLMDKNNEWKLPKDTYYDFDTEAEDQKHDEELKKKQQRTPYIK--RVIAHPNFHNISFNQAEKMMETLDQGDLIIRPSSKGENHLTVTWKVADGIYQHVDVREEGKENAFSLGHTLWINNEEFEDLDEIIARYIQPMASFARDLLGHKYFQDCNGGSREKMEEALIKTKR 1375
[Close]
BLAST of Transcription elongation factor spt6 vs. Planmine SMEST
Match: SMESG000059332.1 (SMESG000059332.1)

HSP 1 Score: 659.833 bits (1701), Expect = 0.000e+0
Identity = 314/322 (97.52%), Postives = 320/322 (99.38%), Query Frame = 1 
Query:    1 QDHRPRFISLTEQERFYFLTNENEETLKIGTVAEFRVINVVNRRNQKDFDNANPKGNKDTGMFSCPICQEDNFHQLSEIWVHFDNQCPGKAVGVNLLFENQIMTFVSIRNIADKFVRNVYDFVKVDQLVVGVVTNISYSKMKLEASLKQSDIKKAFEREKGRRDPHYDEKAENDEKSRKTKHKPSKNNKPIATNTRVSFHPNFKNLNYEQFMKMSHTLRANDFIIRPSSKGPNRLSISWKLSSNLFRHIDVKEEEKKNEFTIGQVLFIDSERFEDLDDIIANYLQPMIGYVDEIFTHKYFKDIRAEDKVTLERMIFEDKRNN 966
            QDHRPRFISLTEQERFYFLTNENEETL IGTVAEFRVINVVNRRNQKDFDNANPKGNKDTG+FSCPICQ+DNFHQLSEIWVHFDNQCPGKA+GVNLLFENQIMTFVSIRNIADKFVRNVYDFVKVDQLVVGVVTN+SYSKMKLEASLKQSDIKKAFEREKGRRDPHYDEKAENDEK+RKTKHKP KNNKPIATNTRVSFHPNFKNLNYEQFMKMSHTLRANDFIIRPSSKGPNRLSISWKLSSNLFRHIDVKEEEKKNEFTIGQVLFIDSERFEDLDDIIANYLQPMIGYVDEIFTHKYFKDIRAEDK+TLERMIFEDKRNN
Sbjct: 1055 QDHRPRFISLTEQERFYFLTNENEETLNIGTVAEFRVINVVNRRNQKDFDNANPKGNKDTGLFSCPICQKDNFHQLSEIWVHFDNQCPGKAIGVNLLFENQIMTFVSIRNIADKFVRNVYDFVKVDQLVVGVVTNVSYSKMKLEASLKQSDIKKAFEREKGRRDPHYDEKAENDEKNRKTKHKPRKNNKPIATNTRVSFHPNFKNLNYEQFMKMSHTLRANDFIIRPSSKGPNRLSISWKLSSNLFRHIDVKEEEKKNEFTIGQVLFIDSERFEDLDDIIANYLQPMIGYVDEIFTHKYFKDIRAEDKLTLERMIFEDKRNN 1376
[Close]
BLAST of Transcription elongation factor spt6 vs. Planmine SMEST
Match: SMESG000058110.1 (SMESG000058110.1)

HSP 1 Score: 280.026 bits (715), Expect = 3.838e-85
Identity = 140/324 (43.21%), Postives = 210/324 (64.81%), Query Frame = 1 
Query:    1 QDHRPRFISLTEQERFYFLTNENEETLKIGTVAEFRVINVVNRRNQKD-FDNANPKGNKDTGMFSCPICQEDNFHQLSEIWVHFDNQ-CPGKAVGVNLLFENQIMTFVSIRNIADKFVRNVYDFVKVDQLVVGVVTNISYSKMKLEASLKQSDIKKAFEREKGRRDPHYDEKAENDEKSRKTKHKPSKNNKPIATNTRVSFHPNFKNLNYEQFMKMSHTLRANDFIIRPSSKGPNRLSISWKLSSNLFRHIDVKEEEKKNEFTIGQVLFIDSERFEDLDDIIANYLQPMIGYVDEIFTHKYFKDIRAEDKVTLERMIFEDKRNN 966
            +D RP+F SL  +ERF  LT E  ETL +GT+ E RV+++ +++ Q+D  D+A+PK N++TG + CP C +D F +L+ +W HFD Q CPGK +GV     N+I  F++ +NI+D  V N+ D +++D +V   V  + Y +++LE S K +D++      + ++D +YDE AEN +K +  + K  K  K +    RV FHP FKN+ Y  F KM   L   +FIIRPSSKG N L++SWK+  N+ RHIDV EE+K N+F++G  L I+ E+FEDLD+IIA+Y+QPM  +  E+ ++KY+K I  ++K  L  MI  +K  N
Sbjct: 1057 EDSRPKFRSLDPKERFELLTKETSETLDVGTLVEARVVSLAHKKPQQDQLDHASPKRNENTGYWICPFCFQDTFPELNNVWQHFDTQECPGKVIGVYCELHNRIRAFLATKNISDNHVTNILDRLELDMMVQARVLKVDYERLQLEISTKSTDLQDLNRAWRKQKDMYYDEFAENQDK-QLIEEKLEKQKKILPYVNRVIFHPQFKNITYNDFEKMCPRLEIGEFIIRPSSKGANHLTVSWKVDENVVRHIDVIEEDKDNDFSLGNTLVIEGEKFEDLDEIIASYVQPMANFAREVQSYKYYKKIDGDNKNLLVDMIRAEKTTN 1379
The following BLAST results are available for this feature:
BLAST of Transcription elongation factor spt6 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 2
Match NameE-valueIdentityDescription
SUPT6H8.999e-6636.65SPT6 homolog, histone chaperone and transcription ... [more]
SUPT6H8.999e-6636.65SPT6 homolog, histone chaperone and transcription ... [more]
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BLAST of Transcription elongation factor spt6 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 1
Match NameE-valueIdentityDescription
emb-51.319e-3731.86Suppressor of Ty 6 homolog [Source:UniProtKB/Swis... [more]
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BLAST of Transcription elongation factor spt6 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 2
Match NameE-valueIdentityDescription
Spt67.709e-5733.23gene:FBgn0028982 transcript:FBtr0070896[more]
Spt67.709e-5733.23gene:FBgn0028982 transcript:FBtr0340027[more]
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BLAST of Transcription elongation factor spt6 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 1
Match NameE-valueIdentityDescription
supt6h6.620e-6435.40SPT6 homolog, histone chaperone and transcription ... [more]
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BLAST of Transcription elongation factor spt6 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
SUPT6H4.878e-6536.65SPT6 homolog, histone chaperone [Source:NCBI gene;... [more]
SUPT6H4.878e-6536.65SPT6 homolog, histone chaperone [Source:NCBI gene;... [more]
SUPT6H5.478e-6536.65SPT6 homolog, histone chaperone [Source:NCBI gene;... [more]
SUPT6H6.119e-6536.65SPT6 homolog, histone chaperone [Source:NCBI gene;... [more]
SUPT6H6.747e-6536.65SPT6 homolog, histone chaperone [Source:NCBI gene;... [more]
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BLAST of Transcription elongation factor spt6 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 1
Match NameE-valueIdentityDescription
Supt63.436e-6636.65SPT6, histone chaperone and transcription elongati... [more]
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BLAST of Transcription elongation factor spt6 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q62383|SPT6H_MOUSE2.403e-6536.65Transcription elongation factor SPT6 OS=Mus muscul... [more]
sp|Q7KZ85|SPT6H_HUMAN4.322e-6536.65Transcription elongation factor SPT6 OS=Homo sapie... [more]
sp|Q8UVK2|SPT6H_DANRE4.997e-6335.40Transcription elongation factor SPT6 OS=Danio reri... [more]
sp|Q9W420|SPT6H_DROME7.728e-5633.23Transcription elongation factor SPT6 OS=Drosophila... [more]
sp|P34703|SPT6H_CAEEL1.677e-3631.86Suppressor of Ty 6 homolog OS=Caenorhabditis elega... [more]
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BLAST of Transcription elongation factor spt6 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
T1DJP16.054e-6937.96Putative transcription elongation factor spt6 (Fra... [more]
T1E3R06.263e-6937.96Putative transcription elongation factor spt6 (Fra... [more]
A0A1S4FF271.101e-6839.14Transcription elongation factor spt6 OS=Aedes aegy... [more]
Q174B11.122e-6839.14Transcription elongation factor spt6 OS=Aedes aegy... [more]
A0A419QG361.495e-6737.12Transcription elongation factor spt6 OS=Clonorchis... [more]
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BLAST of Transcription elongation factor spt6 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 2
Match NameE-valueIdentityDescription
supt6h1.053e-6636.02SPT6 homolog, histone chaperone and transcription ... [more]
supt6h1.220e-6636.02SPT6 homolog, histone chaperone and transcription ... [more]
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BLAST of Transcription elongation factor spt6 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Transcription elongation factor spt6 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 1
Match NameE-valueIdentityDescription
SPT62.664e-2129.41Nucleosome remodeling protein; functions in variou... [more]
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BLAST of Transcription elongation factor spt6 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1
Match NameE-valueIdentityDescription
EDO336021.985e-6335.40Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Transcription elongation factor spt6 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 3
Match NameE-valueIdentityDescription
supt6h4.847e-6537.10SPT6 homolog, histone chaperone and transcription ... [more]
supt6h5.247e-6537.10SPT6 homolog, histone chaperone and transcription ... [more]
supt6h5.293e-6537.10SPT6 homolog, histone chaperone and transcription ... [more]
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BLAST of Transcription elongation factor spt6 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 2
Match NameE-valueIdentityDescription
SMESG000059332.10.000e+097.52SMESG000059332.1[more]
SMESG000058110.13.838e-8543.21SMESG000058110.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30009175 ID=SMED30009175|Name=Transcription elongation factor spt6|organism=Schmidtea mediterranea sexual|type=transcript|length=966bp
CAGGATCATAGGCCCAGATTTATTTCCCTAACTGAACAAGAAAGGTTTTA
CTTTTTGACAAATGAAAATGAAGAGACTCTTAAAATTGGCACTGTCGCTG
AATTTAGAGTCATCAATGTAGTTAACAGAAGAAACCAAAAGGATTTCGAC
AACGCTAATCCTAAAGGAAACAAAGATACAGGCATGTTTTCCTGCCCGAT
TTGTCAGGAAGACAATTTTCACCAGCTTAGTGAAATCTGGGTCCATTTTG
ATAATCAATGTCCAGGAAAGGCAGTCGGAGTAAATTTATTATTTGAAAAT
CAAATTATGACGTTTGTGTCAATAAGAAATATCGCCGATAAGTTCGTAAG
AAATGTTTACGATTTTGTAAAAGTTGATCAATTAGTCGTCGGAGTAGTGA
CAAATATTTCATATTCAAAAATGAAATTGGAAGCTTCTTTAAAGCAATCT
GATATTAAAAAGGCGTTTGAAAGAGAAAAAGGACGTCGAGATCCACATTA
TGATGAAAAGGCTGAAAATGATGAAAAAAGCAGAAAAACGAAACATAAAC
CGAGCAAAAATAATAAGCCCATAGCAACCAATACTCGAGTGTCATTCCAT
CCTAATTTTAAAAACCTTAATTATGAACAGTTCATGAAGATGTCACACAC
GTTACGAGCGAATGATTTTATTATAAGACCAAGCAGTAAAGGACCAAACC
GTTTAAGTATCAGTTGGAAGTTGTCATCAAACCTTTTTCGGCACATTGAT
GTAAAGGAAGAAGAAAAGAAAAATGAGTTCACAATCGGTCAAGTTCTTTT
TATCGATTCGGAAAGATTCGAAGATCTCGATGACATAATCGCCAATTATC
TTCAACCAATGATAGGTTACGTAGACGAGATTTTCACTCACAAATATTTT
AAAGATATTAGAGCTGAAGACAAGGTAACTCTAGAGAGAATGATTTTCGA
AGATAAAAGAAACAAT
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protein sequence of SMED30009175-orf-1

>SMED30009175-orf-1 ID=SMED30009175-orf-1|Name=SMED30009175-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=322bp
QDHRPRFISLTEQERFYFLTNENEETLKIGTVAEFRVINVVNRRNQKDFD
NANPKGNKDTGMFSCPICQEDNFHQLSEIWVHFDNQCPGKAVGVNLLFEN
QIMTFVSIRNIADKFVRNVYDFVKVDQLVVGVVTNISYSKMKLEASLKQS
DIKKAFEREKGRRDPHYDEKAENDEKSRKTKHKPSKNNKPIATNTRVSFH
PNFKNLNYEQFMKMSHTLRANDFIIRPSSKGPNRLSISWKLSSNLFRHID
VKEEEKKNEFTIGQVLFIDSERFEDLDDIIANYLQPMIGYVDEIFTHKYF
KDIRAEDKVTLERMIFEDKRNN
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: molecular function
TermDefinition
GO:0003677DNA binding
GO:0003676nucleic acid binding
GO:0003746translation elongation factor activity
Vocabulary: cellular component
TermDefinition
GO:0005634nucleus
Vocabulary: biological process
TermDefinition
GO:0032968positive regulation of transcription elongation from RNA polymerase II promoter
GO:0006139nucleobase-containing compound metabolic process
GO:0006357regulation of transcription from RNA polymerase II promoter
GO:0006414translational elongation
GO:0032784regulation of DNA-templated transcription, elongation
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000016pharynx
PLANA:0000026gut
PLANA:0000070intestinal phagocyte
PLANA:0000103central nervous system
Vocabulary: INTERPRO
TermDefinition
IPR036860SH2_dom_sf
IPR035420Spt6_SH2
IPR017072TF_Spt6
IPR035019Spt6_SH2_N
IPR000980SH2
IPR012340NA-bd_OB-fold
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR000980SH2 domainSMARTSM00252SH2_5coord: 200..289
e-value: 0.0069
score: 24.6
IPR000980SH2 domainPROSITEPS50001SH2coord: 198..303
score: 9.396
IPR036860SH2 domain superfamilyGENE3DG3DSA:3.30.505.10coord: 192..292
e-value: 2.8E-31
score: 109.4
IPR036860SH2 domain superfamilySUPERFAMILYSSF55550SH2 domaincoord: 205..290
IPR035420Spt6, SH2 domainPFAMPF14633SH2_2coord: 167..321
e-value: 8.5E-43
score: 146.3
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 156..191
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 156..179
NoneNo IPR availableCDDcd00164S1_likecoord: 105..146
e-value: 6.54233E-4
score: 35.4339
IPR017072Transcription elongation factor Spt6PANTHERPTHR10145TRANSCRIPTION ELONGATION FACTOR SPT6coord: 1..321
IPR035019Spt6, SH2 domain, N terminusCDDcd09918SH2_Nterm_SPT6_likecoord: 200..283
e-value: 2.56272E-30
score: 108.094