acid-sensing ion channel 5

Overview
Nameacid-sensing ion channel 5
Smed IDSMED30009148
Length (bp)1998
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of acid-sensing ion channel 5 (SMED30009148) t-SNE clustered cells

Violin plots show distribution of expression levels for acid-sensing ion channel 5 (SMED30009148) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of acid-sensing ion channel 5 (SMED30009148) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for acid-sensing ion channel 5 (SMED30009148) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30009148

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 4

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
nervous systemSMED30009148SMESG000028094.1 dd_Smed_v4_13943_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30009148SMESG000028094.1 dd_Smed_v4_13943_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
non-ciliated neuronSMED30009148SMESG000028094.1 dd_Smed_v4_13943_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
head regionSMED30009148SMESG000028094.1 OX_Smed_1.0.22254ox_Smed_v2PMID:24238224
Kao et al., 2013		whole organism asexual adult RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of acid-sensing ion channel 5 vs. Ensembl Human
Match: ASIC5 (acid sensing ion channel subunit family member 5 [Source:HGNC Symbol;Acc:HGNC:17537])

HSP 1 Score: 79.337 bits (194), Expect = 6.901e-15
Identity = 111/514 (21.60%), Postives = 204/514 (39.69%), Query Frame = 1 
Query:  262 FCRKSTIHGLNHVANSKSVCQRIFWLSICFSASVGLFINMYYLIEKFIERPVLTNI-LQDHAVFSYPDISFCFMNPIYFPPMNTSHFAFLMEKYQEYKHYVAVQE------------EFFKYHIKFGEFLFMKKNQTYTHPAWLAVISCNYLGLPCSHVNFIQRYLFPFGACYTFNSTSVEASDAQFRQHMTTNRELEIIIFKAVDIVPGTISDPFESVLMPSGMLFMIHDKETWPQVRESYVLDG---YSQIDLKIINKVHLNIG-NRCRP-IK-NKFSYYDVFMKTNTSVYGKYSDCVFQNVQQEVSRYCKCQWPKMQALSEFHNLPFCLDGH---LSLIEFGNCVSKAYTILDGGILDECYMD--------DCEHTTYETVISQSKFPAMIERKTQQKWLKILADLEKKEIEHFGKSDLYLRSLKSTNKYQVNLSEALNNKDWSLLDEEFVERNFMMIKVMPTSMFIDKVEETEEYPISRLLSDIGGCVGLWIGASLITIFEFLD-LFMDF 1710
            F   ++ HG++++  ++S  +R+ WL +   +   +   +Y  +  +   P  T+I +Q      +P ++FC +N   F     + F  +   +      + +QE            +F   H  F    F++    Y + + L  + C + G PCS  +F   +   +G C+TFN    E   A+ R+   + R L ++     ++     +D      + +G++F+IH  +  PQ     +L     ++++ ++ +  VH       C P IK   FS Y              S C+ +   Q + + C C             +PF L G+     L ++ +CVS     ++    D C +          CE   Y   IS S FP+       QK LK L+                 + L  + KY                    +  N + I++  + +     ++ +   +S LL+D+GG +GL+ GASLITI E ++ LF +F
Sbjct:   41 FAISTSFHGIHNIVQNRSKIRRVLWLVVVLGSVSLVTWQIYIRLLNYFTWPTTTSIEVQYVEKMEFPAVTFCNLN--RFQTDAVAKFGVIFFLWHIVSKVLHLQEITANSTGSREATDFAASHQNFSIVEFIRNKGFYLNNSTL--LDCEFFGKPCSPKDFAHVFT-EYGNCFTFNHG--ETLQAK-RKVSVSGRGLSLLF----NVNQEAFTDNPALGFVDAGIIFVIHSPKKVPQFDGLGLLSPVGMHARVTIRQVKTVHQEYPWGECNPNIKLQNFSSYST------------SGCLKECKAQHIKKQCGC-------------VPFLLPGYGIECDLQKYFSCVSPVLDHIE--FKDLCTVGTHNSSCPVSCEEIEYPATISYSSFPS-------QKALKYLS-----------------KKLNQSRKY--------------------IRENLVKIEINYSDLNYKITQQQKAVSVSELLADLGGQLGLFCGASLITIIEIIEYLFTNF 471
[Close]
BLAST of acid-sensing ion channel 5 vs. Ensembl Human
Match: SCNN1B (sodium channel epithelial 1 beta subunit [Source:HGNC Symbol;Acc:HGNC:10600])

HSP 1 Score: 59.3066 bits (142), Expect = 2.020e-8
Identity = 82/410 (20.00%), Postives = 162/410 (39.51%), Query Frame = 1 
Query:  547 YKHYVAVQEEFFKYHIKFGEFLFMKKNQT----YTHPAWLAVISCNYLGLPCSHVNFIQRYLFPFGACYTFNSTSVEASDAQFRQHMTTNRELEIII-FKAVDIVPGTISDPFESVLMPSGMLFMIHDKETWPQVRES--YVLDGYSQIDLKIINKVH--------LNIGNRCRPIKNKFSYYDVFMKTNTSVYGKYSDCVFQNVQQEVSRYCKCQWPKMQALSEFHNLPFCL-DGHLSLIEFGNCVSKAYTILDGGILDECYMDDCEHTTYETVISQSKFPAMIERKTQQKWLKILADLEKKEIEHFGKSDLYLRSLKSTNKYQVNLSEALNNKDWSLLDEEFVERNFMMIKVMPTSMFIDKVEETEEYPISRLLSDIGGCVGLWIGASLITIFEFLDLFMDFVETRMI 1728
            ++++ +  +   +++I     +F +  Q      ++P    +++C +   PC++ NF   +   +G CY FN    E   A    +  T   L++I+     D VP   S         +G+  M+H++ ++P +R+   Y + G       +++K+           +     P++N +S Y+        +   + D + +N       Y   +  K     +F +   C  D  +S+ +   C+         G+  E     C  T Y+  IS + +P+    +  + W+  +   E+ +               STN         L+ K    L+  F E N+  I            EE+    I  LLS++GG  G W+G S++ + EF ++ +DFV   +I
Sbjct:  205 FRNFTSATQALTEWYILQATNIFAQVPQQELVEMSYPGEQMILACLFGAEPCNYRNFTSIFYPHYGNCYIFNWGMTE--KALPSANPGTEFGLKLILDIGQEDYVPFLAST--------AGVRLMLHEQRSYPFIRDEGIYAMSGTETSIGVLVDKLQRMGEPYSPCTVNGSEVPVQNFYSDYNTTYSIQACLRSCFQDHMIRNCNCGHYLYPLPRGEKYCNNRDFPDWAHCYSDLQMSVAQRETCI---------GMCKE----SCNDTQYKMTISMADWPS----EASEDWIFHVLSQERDQ---------------STNI-------TLSRKGIVKLNIYFQEFNYRTI------------EESAANNIVWLLSNLGGQFGFWMGGSVLCLIEFGEIIIDFVWITII 553
[Close]
BLAST of acid-sensing ion channel 5 vs. Ensembl Human
Match: SCNN1B (sodium channel epithelial 1 beta subunit [Source:HGNC Symbol;Acc:HGNC:10600])

HSP 1 Score: 58.9214 bits (141), Expect = 2.446e-8
Identity = 82/410 (20.00%), Postives = 162/410 (39.51%), Query Frame = 1 
Query:  547 YKHYVAVQEEFFKYHIKFGEFLFMKKNQT----YTHPAWLAVISCNYLGLPCSHVNFIQRYLFPFGACYTFNSTSVEASDAQFRQHMTTNRELEIII-FKAVDIVPGTISDPFESVLMPSGMLFMIHDKETWPQVRES--YVLDGYSQIDLKIINKVH--------LNIGNRCRPIKNKFSYYDVFMKTNTSVYGKYSDCVFQNVQQEVSRYCKCQWPKMQALSEFHNLPFCL-DGHLSLIEFGNCVSKAYTILDGGILDECYMDDCEHTTYETVISQSKFPAMIERKTQQKWLKILADLEKKEIEHFGKSDLYLRSLKSTNKYQVNLSEALNNKDWSLLDEEFVERNFMMIKVMPTSMFIDKVEETEEYPISRLLSDIGGCVGLWIGASLITIFEFLDLFMDFVETRMI 1728
            ++++ +  +   +++I     +F +  Q      ++P    +++C +   PC++ NF   +   +G CY FN    E   A    +  T   L++I+     D VP   S         +G+  M+H++ ++P +R+   Y + G       +++K+           +     P++N +S Y+        +   + D + +N       Y   +  K     +F +   C  D  +S+ +   C+         G+  E     C  T Y+  IS + +P+    +  + W+  +   E+ +               STN         L+ K    L+  F E N+  I            EE+    I  LLS++GG  G W+G S++ + EF ++ +DFV   +I
Sbjct:  250 FRNFTSATQALTEWYILQATNIFAQVPQQELVEMSYPGEQMILACLFGAEPCNYRNFTSIFYPHYGNCYIFNWGMTE--KALPSANPGTEFGLKLILDIGQEDYVPFLAST--------AGVRLMLHEQRSYPFIRDEGIYAMSGTETSIGVLVDKLQRMGEPYSPCTVNGSEVPVQNFYSDYNTTYSIQACLRSCFQDHMIRNCNCGHYLYPLPRGEKYCNNRDFPDWAHCYSDLQMSVAQRETCI---------GMCKE----SCNDTQYKMTISMADWPS----EASEDWIFHVLSQERDQ---------------STNI-------TLSRKGIVKLNIYFQEFNYRTI------------EESAANNIVWLLSNLGGQFGFWMGGSVLCLIEFGEIIIDFVWITII 598
[Close]
BLAST of acid-sensing ion channel 5 vs. Ensembl Human
Match: SCNN1B (sodium channel epithelial 1 beta subunit [Source:HGNC Symbol;Acc:HGNC:10600])

HSP 1 Score: 58.151 bits (139), Expect = 3.604e-8
Identity = 79/376 (21.01%), Postives = 148/376 (39.36%), Query Frame = 1 
Query:  637 THPAWLAVISCNYLGLPCSHVNFIQRYLFPFGACYTFNSTSVEASDAQFRQHMTTNRELEIII-FKAVDIVPGTISDPFESVLMPSGMLFMIHDKETWPQVRES--YVLDGYSQIDLKIINKVH--------LNIGNRCRPIKNKFSYYDVFMKTNTSVYGKYSDCVFQNVQQEVSRYCKCQWPKMQALSEFHNLPFCL-DGHLSLIEFGNCVSKAYTILDGGILDECYMDDCEHTTYETVISQSKFPAMIERKTQQKWLKILADLEKKEIEHFGKSDLYLRSLKSTNKYQVNLSEALNNKDWSLLDEEFVERNFMMIKVMPTSMFIDKVEETEEYPISRLLSDIGGCVGLWIGASLITIFEFLDLFMDFVETRMI 1728
            ++P    +++C +   PC++ NF   +   +G CY FN    E   A    +  T   L++I+     D VP   S         +G+  M+H++ ++P +R+   Y + G       +++K+           +     P++N +S Y+        +   + D + +N       Y   +  K     +F +   C  D  +S+ +   C+         G+  E     C  T Y+  IS + +P+    +  + W+  +   E+ +               STN         L+ K    L+  F E N+  I            EE+    I  LLS++GG  G W+G S++ + EF ++ +DFV   +I
Sbjct:  212 SYPGEQMILACLFGAEPCNYRNFTSIFYPHYGNCYIFNWGMTE--KALPSANPGTEFGLKLILDIGQEDYVPFLAST--------AGVRLMLHEQRSYPFIRDEGIYAMSGTETSIGVLVDKLQRMGEPYSPCTVNGSEVPVQNFYSDYNTTYSIQACLRSCFQDHMIRNCNCGHYLYPLPRGEKYCNNRDFPDWAHCYSDLQMSVAQRETCI---------GMCKE----SCNDTQYKMTISMADWPS----EASEDWIFHVLSQERDQ---------------STNI-------TLSRKGIVKLNIYFQEFNYRTI------------EESAANNIVWLLSNLGGQFGFWMGGSVLCLIEFGEIIIDFVWITII 526
[Close]
BLAST of acid-sensing ion channel 5 vs. Ensembl Human
Match: AC093830.1 (acid sensing ion channel subunit family member 5 [Source:NCBI gene;Acc:51802])

HSP 1 Score: 57.3806 bits (137), Expect = 5.417e-8
Identity = 87/407 (21.38%), Postives = 161/407 (39.56%), Query Frame = 1 
Query:  262 FCRKSTIHGLNHVANSKSVCQRIFWLSICFSASVGLFINMYYLIEKFIERPVLTNI-LQDHAVFSYPDISFCFMNPIYFPPMNTSHFAFLMEKYQEYKHYVAVQE------------EFFKYHIKFGEFLFMKKNQTYTHPAWLAVISCNYLGLPCSHVNFIQRYLFPFGACYTFNSTSVEASDAQFRQHMTTNRELEIIIFKAVDIVPGTISDPFESVLMPSGMLFMIHDKETWPQVRESYVLDG---YSQIDLKIINKVHLNIG-NRCRP-IK-NKFSYYDVFMKTNTSVYGKYSDCVFQNVQQEVSRYCKCQWPKMQALSEFHNLPFCLDGH---LSLIEFGNCVSKAYTILDGGILDECYMD--------DCEHTTYETVISQSKFPAMIERKTQQKWLKILA 1392
            F   ++ HG++++  ++S  +R+ WL +   +   +   +Y  +  +   P  T+I +Q      +P ++FC +N   F     + F  +   +      + +QE            +F   H  F    F++    Y + + L  + C + G PCS  +F   +   +G C+TFN    E   A+ R+   + R L ++     ++     +D      + +G++F+IH  +  PQ     +L     ++++ ++ +  VH       C P IK   FS Y              S C+ +   Q + + C C             +PF L G+     L ++ +CVS     ++    D C +          CE   Y   IS S FP+       QK LK L+
Sbjct:   41 FAISTSFHGIHNIVQNRSKIRRVLWLVVVLGSVSLVTWQIYIRLLNYFTWPTTTSIEVQYVEKMEFPAVTFCNLN--RFQTDAVAKFGVIFFLWHIVSKVLHLQEITANSTGSREATDFAASHQNFSIVEFIRNKGFYLNNSTL--LDCEFFGKPCSPKDFAHVFT-EYGNCFTFNHG--ETLQAK-RKVSVSGRGLSLLF----NVNQEAFTDNPALGFVDAGIIFVIHSPKKVPQFDGLGLLSPVGMHARVTIRQVKTVHQEYPWGECNPNIKLQNFSSYST------------SGCLKECKAQHIKKQCGC-------------VPFLLPGYGIECDLQKYFSCVSPVLDHIE--FKDLCTVGTHNSSCPVSCEEIEYPATISYSSFPS-------QKALKYLS 401
[Close]
BLAST of acid-sensing ion channel 5 vs. Ensembl Celegans
Match: asic-2 (Degenerin-like protein asic-2 [Source:UniProtKB/Swiss-Prot;Acc:Q22851])

HSP 1 Score: 64.3142 bits (155), Expect = 1.715e-10
Identity = 55/187 (29.41%), Postives = 88/187 (47.06%), Query Frame = 1 
Query:  262 FCRKSTIHGLNHVANSKSVCQRIFWLSICFSASVGLFI-NMYYLIEKFIERP--VLTNILQDHAVFSYPDISFCFMNPIYFPPMNT----SHFAFLMEKYQEYK---------HYVAVQEEFFKYHIKFGEFLFMKKN---QTYTHPAWLA----VISCNYLGLPCSHVNFIQRYLFP-FGACYTFN 750
            F   ST+  + HVAN+ +   RIFW++I F   +G+F   +Y LI KF   P  V T IL +  +F  P ++ C MNP  +  + +    S    LM  Y +              A  +E +    +  + L ++ N    T   PA       +  C++ G+PCS  +F  +++ P +GACY+FN
Sbjct:   13 FSNWSTVAVVPHVANANNKISRIFWIAI-FLFVLGMFAYELYILIAKFFSYPATVNTEILFEKQIF--PVVTVCNMNPYKYSVVKSNSAFSSVNTLMTTYSDATVGTFSTDKWGLYADNDETYDLDSRAADALVLEANLISDTAKVPALYTYADLIQDCSFAGIPCSESDFT-KFIDPVYGACYSFN 195
[Close]
BLAST of acid-sensing ion channel 5 vs. Ensembl Celegans
Match: del-4 (DEgenerin Like [Source:UniProtKB/TrEMBL;Acc:P91835])

HSP 1 Score: 58.151 bits (139), Expect = 1.252e-8
Identity = 111/507 (21.89%), Postives = 196/507 (38.66%), Query Frame = 1 
Query:  265 CRKSTIHGLNHVANSKSVCQRIFWLSICFSASVGLFINMYY-LIEKFIERPVLTNILQDHAVFSYPDISFCFMNPIYFPPMNT--SHFAFLMEKYQEYKHYVAV----------QEEFFKYHIKFGEFLFMKKNQTYTHPAWLA------VISCNYLGLPCSHVNFIQRYLFPFGACYTFNSTSVEASDAQFRQHMTTNRELEIIIFKAVDIVPGTISDPFESVLMPSGMLFMIH--DKETWPQVRESYVLDG-YSQIDLKIINKVHLNIGNRCRPIKNKFSYYDVFMKTNTSVYGKYSDCVFQNVQQEVSRYCKCQWPKMQALSEFHNLPFCLDGHLSLIEFGNCV----SKAYTILDGGILDECYM-DDCEHTTYETVISQSKFPAMIERKTQQKWLKILADLEKKEIEHFGKSDLYLRSLKST-NKYQVNLSEALNNKDWSLLDEEFVER-NFMMIKVMPTSMFIDKVEETEEYPISRLLSDIGGCVGLWIGASLITIFEFLDL 1698
            C  ST HG+ H+  + +   R FW+ +    S+ LFI  +  L+  ++   V T      A  ++P ++ C +NP       +     + L++ Y                   Q++  K+ + + E L  K+   Y   A +A      V+SC Y    C+  +F   Y   +G C  FN+  + +S          +R   +   +   +V  T  D +      SG++  IH  D+  +P V   +   G  S + +  +    L+     +P  +  +   +     T  Y     C    +Q+++   C C +P     S       C +G  +L    NCV    S   T  D  +L +C     CE  +Y   +S +++P+     T              E    G S  +  S +S  + Y+ N          ++L E + ER NF ++   P   F++             +SD+GG VGL++G S+I+  E+L L
Sbjct:   17 CWTST-HGVPHIGMANARWLRAFWILVVV-VSIALFIWQFITLLTNYLSFSVNTETTLQFAERTFPTVTICHLNPWKLSETKSVDPDMSALIDAYNSDSSSAQFGLPASLTADRQQQASKWTLMYSERLNEKQ---YNDAADIAYSYDDMVVSCTYNAKTCNITDFNDFYNPSYGNCLQFNTDGMYSS----------SRAGPLYGLR---MVMRTDQDTYLPWTEASGVIIDIHMQDEIPYPDVFGYFAPPGTASSLGVSYVQTTRLS-----KPYGSCTTKTKLKTTHYTGTY-TVEACFRSCMQEKIIASCGCYYPAYSHASNTTQYVSCDNGVQTLSNL-NCVDLINSADSTEFD--VLTDCDCPQPCEIDSYGVTVSTAQWPSDSYVPT--------------ECNPGGPSGPWDASGESCLDWYKAN----------TILIEIYYERMNFQVLTESPAYTFVN------------FISDVGGQVGLFLGMSIISAIEYLVL 460
[Close]
BLAST of acid-sensing ion channel 5 vs. Ensembl Celegans
Match: delm-1 (DEgenerin Linked to Mechanosensation [Source:UniProtKB/TrEMBL;Acc:O45402])

HSP 1 Score: 50.447 bits (119), Expect = 4.039e-6
Identity = 46/173 (26.59%), Postives = 84/173 (48.55%), Query Frame = 1 
Query: 1429 SDLYLRSLKSTNKYQVNLSEALNNKD--WSLLDEEFVERNFMMIKVMPTSMFIDKVEETEEYPISRLLSDIGGCVGLWIGASLITIFEFLDLFMDFVETRMIPAKQTKPREHL----KNTLLSKKYLILNCNKLSKLDSIYENSATLNLANLKCTKVTLKESFSEKDI-FKIS 1926
            S +Y     + N++        N+K+  WS+   ++++ NF MI++    M   +  + ++  I+ LLS IGG +G+++G S+ITI E   LF+ F +   I   +T+ R +L     N    KK ++     + K+  I       +L++  C    LK S   K + F+I+
Sbjct:  436 SQVYRADNSNGNQFSAGAFNYFNSKNSSWSV---DYMKSNFQMIRIFYRDMSYTEYNQVQDASITDLLSAIGGNMGMFLGGSVITIVE---LFLFFSKVFWIGFSKTR-RNYLYSKRANEKAHKKEVV---ETVEKMKVIASQGNLTSLSDATCATPPLKLSSPNKKVEFRIN 598
[Close]
BLAST of acid-sensing ion channel 5 vs. Ensembl Celegans
Match: unc-8 (Degenerin unc-8 [Source:UniProtKB/Swiss-Prot;Acc:Q21974])

HSP 1 Score: 50.0618 bits (118), Expect = 5.711e-6
Identity = 23/61 (37.70%), Postives = 36/61 (59.02%), Query Frame = 1 
Query: 1525 EFVERNFMMIKVMPTSMFIDKVEETEEYPISRLLSDIGGCVGLWIGASLITIFEFLDLFMD 1707
            E+  +N   I++    +  + ++ET  Y +  L SD GG +GLWIG S+IT  EF +LF +
Sbjct:  618 EYYRQNTAYIEIYYEQLNFESLKETAGYTLVNLFSDFGGNIGLWIGFSVITFAEFAELFCE 678
[Close]
BLAST of acid-sensing ion channel 5 vs. Ensembl Celegans
Match: unc-8 (Degenerin unc-8 [Source:UniProtKB/Swiss-Prot;Acc:Q21974])

HSP 1 Score: 49.6766 bits (117), Expect = 6.439e-6
Identity = 23/61 (37.70%), Postives = 36/61 (59.02%), Query Frame = 1 
Query: 1525 EFVERNFMMIKVMPTSMFIDKVEETEEYPISRLLSDIGGCVGLWIGASLITIFEFLDLFMD 1707
            E+  +N   I++    +  + ++ET  Y +  L SD GG +GLWIG S+IT  EF +LF +
Sbjct:  657 EYYRQNTAYIEIYYEQLNFESLKETAGYTLVNLFSDFGGNIGLWIGFSVITFAEFAELFCE 717
[Close]
BLAST of acid-sensing ion channel 5 vs. Ensembl Zebrafish
Match: asic1c (acid-sensing (proton-gated) ion channel 1c [Source:NCBI gene;Acc:407670])

HSP 1 Score: 80.4925 bits (197), Expect = 2.091e-15
Identity = 113/522 (21.65%), Postives = 205/522 (39.27%), Query Frame = 1 
Query:  262 FCRKSTIHGLNHVANSKSVCQRIFWLSICFSASVGLFINMYYLIEK---FIERPVLTNILQDHAV-FSYPDISFCFMNPIYFPPMNTSHF-------AFLMEKYQEYKHYVAVQE--EFFKYHIKFGEFLFMKKNQT-----YTHPAWLAVISCNYLGLPCSHVNFIQRYLFPFGACYTFNSTSVEASDAQFRQHMTTNRELEIIIFKAVDIVPGTISDPFESVLMPSGMLFMIHDKETWPQVRE-SYVLDGYSQIDLKIINKVHLNIG---NRCRPIKNKFSYYDVFMKTNTSVYGKYSDCVFQNVQQEVSRYCKCQWPKMQALSEFHNLPFCLDGHLSLIEFGNCVSKAYTILDGGILDECYMDD-CEHTTYETVISQSKFPAMIERKTQQKWLKILADLEKKEIEHFGKSDLYLRSLKSTNKYQVNLSEALNNKDWSLLDEEFVERNFMMIKVMPTSMFIDKVEETEEYPISRLLSDIGGCVGLWIGASLITIFEFLDLFMDFVETRMIPAKQTKPREH 1758
            F   ST+HG++H+     +  R F  ++ F  S+GL   MY  +++   + E P +T + +  A   ++P ++FC +N   F  +  +         A L E YQ    ++A  E     K    F  F   + N T       H     ++ C++ G  C  +NF   Y   +G CYTFNS  ++ +         T   LEI++    D       D  E+    +G+   IH ++  P + +  + +    Q  +    ++ L +      CR       Y+  +  T   +     DC  + + +     C C+   M   S             +  ++ +C   A   L     D C  D  C  T Y   +S  K P+                                   K++ KY   L++  N        E+++  N +++ +   ++  +K+E+ + Y ++ LL DIGG +GL+IGAS++TI E  D   + ++ +++ +   K R H
Sbjct:   23 FANNSTLHGMSHIFAYGHMTFRRFLWTLSFMGSLGLL--MYVCMDRVYYYFEFPHVTKLDEVAAPNLTFPAVTFCNLNEFRFSKITKNDLYHVGELLALLNENYQIANPHLADPEVLTLLKEKASFNGFKPKQFNMTDFYNRTGHDINEMLLQCSFRGEECFPLNFTTIYT-RYGKCYTFNS-GLDGNPLLTTLKGGTGNGLEIMLDIQQDEYLPVWGDTDETS-YEAGIKVQIHSQDEPPFIDQLGFGVAPGFQTFVSCQQQLLLYLPPPWGDCRSAPMDSEYFSTYSITACRI-----DCETRYLLEN----CNCRMVHMPGTSTV----------CTPEQYKDCADPALDFLVEKDNDYCVCDTPCNMTRYGKELSMVKIPS-----------------------------------KASAKY---LAKKFNKT------EQYITDNILVLDIFFEALNYEKIEQKKAYEVAGLLGDIGGQMGLFIGASVLTILEIFDYLYEVLKDKILGSVLRKRRPH 476
[Close]
BLAST of acid-sensing ion channel 5 vs. Ensembl Zebrafish
Match: asic1c (acid-sensing (proton-gated) ion channel 1c [Source:NCBI gene;Acc:407670])

HSP 1 Score: 56.6102 bits (135), Expect = 2.128e-8
Identity = 24/79 (30.38%), Postives = 50/79 (63.29%), Query Frame = 1 
Query: 1522 EEFVERNFMMIKVMPTSMFIDKVEETEEYPISRLLSDIGGCVGLWIGASLITIFEFLDLFMDFVETRMIPAKQTKPREH 1758
            E+++  N +++ +   ++  +K+E+ + Y ++ LL DIGG +GL+IGAS++TI E  D   + ++ +++ +   K R H
Sbjct:  118 EQYITDNILVLDIFFEALNYEKIEQKKAYEVAGLLGDIGGQMGLFIGASVLTILEIFDYLYEVLKDKILGSVLRKRRPH 196
[Close]
BLAST of acid-sensing ion channel 5 vs. Ensembl Zebrafish
Match: asic4b (acid-sensing (proton-gated) ion channel family member 4b [Source:NCBI gene;Acc:407667])

HSP 1 Score: 58.151 bits (139), Expect = 2.481e-8
Identity = 28/83 (33.73%), Postives = 52/83 (62.65%), Query Frame = 1 
Query: 1522 EEFVERNFMMIKVMPTSMFIDKVEETEEYPISRLLSDIGGCVGLWIGASLITIFEFLDLFMDFVETRMIPAKQTKPREHLKNT 1770
            EE++  NF+++ +   ++  + +E+ + Y I+ LL DIGG +GL+IGAS++TI E LD   +  + ++   +  KP++  K T
Sbjct:  404 EEYIRDNFLILDIFFEALNYETIEQKKAYDIAGLLGDIGGQMGLFIGASILTILEILDYIYEVAKNKI--KQLLKPKKSQKQT 484
[Close]
BLAST of acid-sensing ion channel 5 vs. Ensembl Zebrafish
Match: asic4a (acid-sensing (proton-gated) ion channel family member 4a [Source:NCBI gene;Acc:407668])

HSP 1 Score: 57.3806 bits (137), Expect = 2.846e-8
Identity = 50/212 (23.58%), Postives = 86/212 (40.57%), Query Frame = 1 
Query: 1093 SDCVFQNVQQEVSRYCKCQWPKMQALSEFHNLPFCLDGHLSLIEFGNCVSKAYTILDGGILDECYMD-DCEHTTYETVISQSKFPAMIERKTQQKWLKILADLEKKEIEHFGKSDLYLRSLKSTNKYQVNLSEALNNKDWSLLDEEFVERNFMMIKVMPTSMFIDKVEETEEYPISRLLSDIGGCVGLWIGASLITIFEFLDLFMDFVETRM 1725
            S C  +    EV R CKC+   M             D ++       CV KA  +L     D C+ +  C  T Y   +S  K P+    K   ++L                          + KY  +              E+++  NF+++ +   ++  + +E+ + Y ++ LL DIGG +GL+IGAS++TI E LD   + ++ R+
Sbjct:  119 SACRLRCETLEVLRECKCRMVHMPG-----------DANICTPSDIKCVDKALALLQKSSGDTCFCETPCNLTRYGKELSMVKIPS----KGSARYL--------------------------SRKYDKS--------------EDYIRDNFLVLDIFFEALNYETIEQKKAYDVAGLLGDIGGQMGLFIGASVLTILEILDYVYEVIKHRL 275
[Close]
BLAST of acid-sensing ion channel 5 vs. Ensembl Zebrafish
Match: asic4a (acid-sensing (proton-gated) ion channel family member 4a [Source:NCBI gene;Acc:407668])

HSP 1 Score: 56.9954 bits (136), Expect = 4.840e-8
Identity = 50/212 (23.58%), Postives = 86/212 (40.57%), Query Frame = 1 
Query: 1093 SDCVFQNVQQEVSRYCKCQWPKMQALSEFHNLPFCLDGHLSLIEFGNCVSKAYTILDGGILDECYMD-DCEHTTYETVISQSKFPAMIERKTQQKWLKILADLEKKEIEHFGKSDLYLRSLKSTNKYQVNLSEALNNKDWSLLDEEFVERNFMMIKVMPTSMFIDKVEETEEYPISRLLSDIGGCVGLWIGASLITIFEFLDLFMDFVETRM 1725
            S C  +    EV R CKC+   M             D ++       CV KA  +L     D C+ +  C  T Y   +S  K P+    K   ++L                          + KY  +              E+++  NF+++ +   ++  + +E+ + Y ++ LL DIGG +GL+IGAS++TI E LD   + ++ R+
Sbjct:  311 SACRLRCETLEVLRECKCRMVHMPG-----------DANICTPSDIKCVDKALALLQKSSGDTCFCETPCNLTRYGKELSMVKIPS----KGSARYL--------------------------SRKYDKS--------------EDYIRDNFLVLDIFFEALNYETIEQKKAYDVAGLLGDIGGQMGLFIGASVLTILEILDYVYEVIKHRL 467
[Close]
BLAST of acid-sensing ion channel 5 vs. Ensembl Xenopus
Match: ASIC5 (acid sensing ion channel subunit family member 5 [Source:HGNC Symbol;Acc:HGNC:17537])

HSP 1 Score: 72.4034 bits (176), Expect = 9.460e-13
Identity = 118/516 (22.87%), Postives = 202/516 (39.15%), Query Frame = 1 
Query:  262 FCRKSTIHGLNHVANSKSVCQRIFWLSICFSASVGLFINMY-----YLIEKFIERPVLTNI-LQDHAVFSYPDISFCFMNPIYFPPMNTSHFAF-LMEKYQEYKHYVAV-------QE--EFFKYHIKFGEFLFMKKNQTYTHPAWLAVISCNYLGLPCSHVNFIQRYLFPFGACYTFNSTSVEASDAQFRQHMTTNRELEIIIFKAVDIVPGTISDPFESVLMPSGMLFMIHDKETWPQVRESYVLDGYSQIDLKIINKVHLNIGNR-------------CRPIKNKFSYYDVFMKTNTSVYGKYSDCVFQNVQQEVSRYCKCQWPKMQALSEFHNLPFCLDGH---LSLIEFGNCVSKA-YTILDG-----GILDECYMDDCEHTTYETVISQSKFPAMIERKTQQKWLKILADLEKKEIEHFGKSDLYLRSLKSTNKYQVNLSEALNNKDWSLLDEEFVERNFMMIKVMPTSMFIDKVEETEEYPISRLLSDIGGCVGLWIGASLITIFEFLD 1695
            F   ++ HG++++  +    +   + +  +++ V +FI M        +  +   P  T++ +Q      +P I+FC +N      +N    AF L        H+ ++       QE  +F K +  F    F K    Y + + L  + C++ G PC   +F +     +G CYTFN  +V  +    ++  T  R L ++     DI     +D      + +G+ F++H     P+       DG   + L     +H ++  R             C P   K  Y++++     S YG   +C    +Q E    C C             +PF L G+     L +  NCVS+A YTI        G  +      CE T +   IS S FP+        K  + L+           KS LY+R+                  +   +D ++ E N+ ++K            + +    S LLS+IGG +GL+ GAS+ITI E L+
Sbjct:   40 FATSTSFHGVHNLVENGGSGKNSKFRTAIWTSVVSVFIIMACWQVCTRVINYFSWPTTTSVNVQYVENIDFPAITFCNLNRFQTKAVNNLSIAFFLWNIVSAVLHFTSIASDPGEMQEVTDFLKLNKNFSIKEFTKNYGFYLNNSTL--LKCSFFGYPCYPEDF-EHIFTEYGNCYTFNYNTVSMN----KRITTAGRGLSVLF----DIKQTEFTDEPSLGFVDAGISFVLHSPLVPPR------FDG---LGLHSPAGMHAHVSMRRFKTVIQEHPWGECNP-SLKLKYHEIY-----STYGCLQECKSYYIQNE----CGC-------------IPFLLPGNGKECDLQQLYNCVSRALYTIEKSELCSMGTYNSTCPVPCEETDFPATISYSTFPS-------DKAAQFLS-------AKLSKSALYMRN------------------NLVYIDIKYHEMNYKIMK------------QQKALTASELLSNIGGQLGLFCGASMITIIEILE 468
[Close]
BLAST of acid-sensing ion channel 5 vs. Ensembl Xenopus
Match: ASIC4 (acid sensing ion channel subunit family member 4 [Source:NCBI gene;Acc:100486325])

HSP 1 Score: 54.299 bits (129), Expect = 4.294e-7
Identity = 28/92 (30.43%), Postives = 53/92 (57.61%), Query Frame = 1 
Query: 1519 DEEFVERNFMMIKVMPTSMFIDKVEETEEYPISRLLSDIGGCVGLWIGASLITIFEFLDLFMDFVE---TRMIPAKQT---KPREHLKNTLL 1776
            +E ++  NF+++ +   ++  + +E+ + Y +  LL DIGG +GL+IGAS +TI E LD   + +     R+   KQ+   KP E++   ++
Sbjct:  356 NETYIRENFLVLDIFFEALNYETIEQKKAYDLPSLLGDIGGQMGLFIGASFLTILEILDYMYEVIRDKVKRVAGRKQSPAKKPSENIATLVM 447
[Close]
BLAST of acid-sensing ion channel 5 vs. Ensembl Xenopus
Match: ASIC4 (acid sensing ion channel subunit family member 4 [Source:NCBI gene;Acc:100486325])

HSP 1 Score: 53.1434 bits (126), Expect = 1.172e-6
Identity = 22/66 (33.33%), Postives = 42/66 (63.64%), Query Frame = 1 
Query: 1519 DEEFVERNFMMIKVMPTSMFIDKVEETEEYPISRLLSDIGGCVGLWIGASLITIFEFLDLFMDFVE 1716
            +E ++  NF+++ +   ++  + +E+ + Y +  LL DIGG +GL+IGAS +TI E LD   + ++
Sbjct:  356 NETYIRENFLVLDIFFEALNYETIEQKKAYDLPSLLGDIGGQMGLFIGASFLTILEILDYMYEVIQ 421
[Close]
BLAST of acid-sensing ion channel 5 vs. Ensembl Xenopus
Match: ASIC4 (acid sensing ion channel subunit family member 4 [Source:NCBI gene;Acc:100486325])

HSP 1 Score: 51.6026 bits (122), Expect = 3.194e-6
Identity = 22/59 (37.29%), Postives = 39/59 (66.10%), Query Frame = 1 
Query: 1519 DEEFVERNFMMIKVMPTSMFIDKVEETEEYPISRLLSDIGGCVGLWIGASLITIFEFLD 1695
            +E ++  NF+++ +   ++  + +E+ + Y +  LL DIGG +GL+IGAS +TI E LD
Sbjct:  356 NETYIRENFLVLDIFFEALNYETIEQKKAYDLPSLLGDIGGQMGLFIGASFLTILEILD 414
[Close]
BLAST of acid-sensing ion channel 5 vs. Ensembl Xenopus
Match: ASIC1 (acid sensing ion channel subunit 1 [Source:NCBI gene;Acc:100489966])

HSP 1 Score: 51.2174 bits (121), Expect = 4.023e-6
Identity = 23/74 (31.08%), Postives = 45/74 (60.81%), Query Frame = 1 
Query: 1522 EEFVERNFMMIKVMPTSMFIDKVEETEEYPISRLLSDIGGCVGLWIGASLITIFEFLDLFMDFVETRMIPAKQT 1743
            E+++  N +++ +   ++  + +E+ + Y ++ LL DIGG +GL+IGAS++T+ E  D      E RM+   +T
Sbjct:  398 EQYIAENILVLDIFFEALNYETIEQKKAYEVAGLLGDIGGQMGLFIGASILTVLELFDYAY---EVRMLSCAET 468
[Close]
BLAST of acid-sensing ion channel 5 vs. Ensembl Mouse
Match: Asic5 (acid-sensing (proton-gated) ion channel family member 5 [Source:MGI Symbol;Acc:MGI:1929259])

HSP 1 Score: 91.2781 bits (225), Expect = 7.256e-19
Identity = 112/513 (21.83%), Postives = 210/513 (40.94%), Query Frame = 1 
Query:  262 FCRKSTIHGLNHVANSKSVCQRIFWLSICFSASVGLFINMYYLIEKFIERPVLTNI-LQDHAVFSYPDISFCFMNPIYFPPMNTSHFAFLMEKYQEYKHYVAVQE------------EFFKYHIKFGEFLFMKKNQTYTHPAWLAVISCNYLGLPCSHVNFIQRYLFP-FGACYTFNSTSVEASDAQFRQHMT-TNRELEIIIFKAVDIVPGTISDPFESVLMPSGMLFMIHDKETWPQ---VRESYVLDGYSQIDLKIINKVHLNIG-NRCRP---IKNKFSYYDVFMKTNTSVYGKYSDCVFQNVQQEVSRYCKCQWPKMQALSEFHNLPFCLDGH---LSLIEFGNCVSKAYTILDGGILDECYMD--------DCEHTTYETVISQSKFPAMIERKTQQKWLKILADLEKKEIEHFGKSDLYLRSLKSTNKYQVNLSEALNNKDWSLLDEEFVERNFMMIKVMPTSMFIDKVEETEEYPISRLLSDIGGCVGLWIGASLITIFEFLDLF 1701
            F   ++ HG++++A +++  +++ WL++   +   L   +Y  +  +   P  T+I +Q      +P ++ C +N   F     S F  +   +      + +QE            +F   H  F    F+K N  Y +   L  + C + G  CS  +F  +++F  +G C+TFN       + Q +  ++ + R L++++    D+     +D        +G++F+IH  +  PQ   +  S  +  ++++ ++ +  VH       C P   ++N  +Y         S YG   +C  +++Q    R C C             LPF L G+     L+E+ NCVS     ++   L  C M          CE T Y   +S S FP+       Q+  + LA                    K  N+ Q                 E++  N + I++  + +     ++ +   +  LL+D+GG +GL+ GASLITI E ++ F
Sbjct:   41 FAMSTSFHGIHNIAQNQNKVRKVIWLAVVLGSVSLLVWQIYSRLVNYFTWPTTTSIEVQYVEKIEFPAVTLCNLN--RFQTEAVSRFGIIFFLWDIVSKVLRLQEISANNTGSPETLDFVTNHQNFSITEFVKNNGFYLNNDTL--VHCEFFGKTCSPKDF--KHVFTEYGNCFTFNY----GENIQNKNKVSVSGRGLKLLL----DVHQEEFTDNPVPGFADAGVIFVIHSPKKEPQFDGLGLSSPVGMHARVTIRQLKTVHQEYPWGECNPNIKLRNFITY---------STYGCLKECKARHIQ----RLCGC-------------LPFLLPGNGVECDLLEYYNCVSPILDHIERKGL--CTMGTHNSSCPVSCEETEYPATVSYSTFPS-------QRATRFLA--------------------KKLNQSQ-----------------EYIRENLVNIEINYSDLNYKITQQQKAVSVPELLADVGGQLGLFCGASLITIIEIIEYF 467
[Close]
BLAST of acid-sensing ion channel 5 vs. Ensembl Mouse
Match: Asic5 (acid-sensing (proton-gated) ion channel family member 5 [Source:MGI Symbol;Acc:MGI:1929259])

HSP 1 Score: 88.9669 bits (219), Expect = 3.140e-18
Identity = 112/510 (21.96%), Postives = 209/510 (40.98%), Query Frame = 1 
Query:  274 STIHGLNHVANSKSVCQRIFWLSICFSASVGLFINMYYLIEKFIERPVLTNI-LQDHAVFSYPDISFCFMNPIYFPPMNTSHFAFLMEKYQEYKHYVAVQE------------EFFKYHIKFGEFLFMKKNQTYTHPAWLAVISCNYLGLPCSHVNFIQRYLFP-FGACYTFNSTSVEASDAQFRQHMT-TNRELEIIIFKAVDIVPGTISDPFESVLMPSGMLFMIHDKETWPQ---VRESYVLDGYSQIDLKIINKVHLNIG-NRCRP---IKNKFSYYDVFMKTNTSVYGKYSDCVFQNVQQEVSRYCKCQWPKMQALSEFHNLPFCLDGH---LSLIEFGNCVSKAYTILDG---------GILDECYMDDCEHTTYETVISQSKFPAMIERKTQQKWLKILADLEKKEIEHFGKSDLYLRSLKSTNKYQVNLSEALNNKDWSLLDEEFVERNFMMIKVMPTSMFIDKVEETEEYPISRLLSDIGGCVGLWIGASLITIFEFLDLF 1701
            ++ HG++++A +++  +++ WL++   +   L   +Y  +  +   P  T+I +Q      +P ++ C +N   F     S F  +   +      + +QE            +F   H  F    F+K N  Y +   L  + C + G  CS  +F  +++F  +G C+TFN       + Q +  ++ + R L++++    D+     +D        +G++F+IH  +  PQ   +  S  +  ++++ ++ +  VH       C P   ++N  +Y         S YG   +C  +++Q    R C C             LPF L G+     L+E+ NCVS    ILD          G  +      CE T Y   +S S FP+       Q+  + LA                    K  N+ Q                 E++  N + I++  + +     ++ +   +  LL+D+GG +GL+ GASLITI E ++ F
Sbjct:    3 TSFHGIHNIAQNQNKVRKVIWLAVVLGSVSLLVWQIYSRLVNYFTWPTTTSIEVQYVEKIEFPAVTLCNLN--RFQTEAVSRFGIIFFLWDIVSKVLRLQEISANNTGSPETLDFVTNHQNFSITEFVKNNGFYLNNDTL--VHCEFFGKTCSPKDF--KHVFTEYGNCFTFNY----GENIQNKNKVSVSGRGLKLLL----DVHQEEFTDNPVPGFADAGVIFVIHSPKKEPQFDGLGLSSPVGMHARVTIRQLKTVHQEYPWGECNPNIKLRNFITY---------STYGCLKECKARHIQ----RLCGC-------------LPFLLPGNGVECDLLEYYNCVSP---ILDHIERKGLCTMGTHNSSCPVSCEETEYPATVSYSTFPS-------QRATRFLA--------------------KKLNQSQ-----------------EYIRENLVNIEINYSDLNYKITQQQKAVSVPELLADVGGQLGLFCGASLITIIEIIEYF 425
[Close]
BLAST of acid-sensing ion channel 5 vs. Ensembl Mouse
Match: Scnn1b (sodium channel, nonvoltage-gated 1 beta [Source:MGI Symbol;Acc:MGI:104696])

HSP 1 Score: 57.3806 bits (137), Expect = 5.218e-8
Identity = 81/358 (22.63%), Postives = 136/358 (37.99%), Query Frame = 1 
Query:  658 VISCNYLGLPCSHVNFIQRYLFPFGACYTFNSTSVEASDAQFRQHMTTNRELEIIIFKAVDIVPGTISDPFESVLMPSGMLFMIHDKETWPQVRES--YVLDGYSQIDLKIINKVHLNIGNRCRPIKNKFSYYDVFMKTNTSVYG-KYS--DCVFQNVQQEVSRYCKCQ---WPKMQALS-----EFHNLPFC-LDGHLSLIEFGNCVSKAYTILDGGILDECYMDDCEHTTYETVISQSKFPAMIERKTQQKWLKILADLEKKEIEHFGKSDLYLRSLKSTNKYQVNLSEALNNKDWSLLDEEFVERNFMMIKVMPTSMFIDKVEETEEYPISRLLSDIGGCVGLWIGASLITIFEF 1689
            +++C +   PCSH NF   +   +G CY FN    E +            +L I+     D VP   S         +G   M+H++ T+P +RE   Y + G       +++K+    G    P     S  DV +K   SVY   YS   C+    Q  + R C C    +P  +        +F +  +C L+  +S+ +   C+S                + C  T Y+  IS + +P+    +  + W+  +   E+ +  +                        L+ K    L+  F E N+  I            EE+    I  LLS++GG  G W+G S++ + EF
Sbjct:  244 ILACLFGTEPCSHRNFTPIFYPDYGNCYIFNWGMTEETLPSANPGTEFGLKL-ILDIGQEDYVPFLAST--------AGARLMLHEQRTYPFIREEGIYAMAGTETSIGVLVDKLQRK-GEPYSPCTMNGS--DVAIKNLYSVYNTTYSIQACLHSCFQDHMIRNCSCGHYLYPLPEGEKYCNNRDFPDWAYCYLNLQMSVTQRETCLSMC-------------KESCNDTQYKMTISMADWPS----EASEDWILHVLSQERDQSSNI----------------------TLSRKGIVKLNIYFQEFNYRTI------------EESPANNIVWLLSNLGGQFGFWMGGSVLCLIEF 538
[Close]
BLAST of acid-sensing ion channel 5 vs. Ensembl Mouse
Match: Asic3 (acid-sensing (proton-gated) ion channel 3 [Source:MGI Symbol;Acc:MGI:2159339])

HSP 1 Score: 55.0694 bits (131), Expect = 2.171e-7
Identity = 25/69 (36.23%), Postives = 43/69 (62.32%), Query Frame = 1 
Query: 1522 EEFVERNFMMIKVMPTSMFIDKVEETEEYPISRLLSDIGGCVGLWIGASLITIFEFLDLFMDFVETRMI 1728
            E ++  N +++ +   ++  + VE+   Y +S LL DIGG +GL+IGASL+TI E LD   +  + R++
Sbjct:  400 ETYITENVLVLDIFFEALNYEAVEQKAAYEVSELLGDIGGQMGLFIGASLLTILEILDYLCEVFQDRVL 468
[Close]
BLAST of acid-sensing ion channel 5 vs. Ensembl Mouse
Match: Asic2 (acid-sensing (proton-gated) ion channel 2 [Source:MGI Symbol;Acc:MGI:1100867])

HSP 1 Score: 52.7582 bits (125), Expect = 1.250e-6
Identity = 20/69 (28.99%), Postives = 45/69 (65.22%), Query Frame = 1 
Query: 1522 EEFVERNFMMIKVMPTSMFIDKVEETEEYPISRLLSDIGGCVGLWIGASLITIFEFLDLFMDFVETRMI 1728
            E+++  N +++ +   ++  + +E+ + Y ++ LL DIGG +GL+IGAS++TI E  D   + ++ +++
Sbjct:  395 EKYISENILVLDIFFEALNYETIEQKKAYEVAALLGDIGGQMGLFIGASILTILELFDYIYELIKEKLL 463
[Close]
BLAST of acid-sensing ion channel 5 vs. UniProt/SwissProt
Match: sp|Q9R0Y1|ASIC5_MOUSE (Acid-sensing ion channel 5 OS=Mus musculus OX=10090 GN=Asic5 PE=2 SV=1)

HSP 1 Score: 91.2781 bits (225), Expect = 5.075e-18
Identity = 112/513 (21.83%), Postives = 210/513 (40.94%), Query Frame = 1 
Query:  262 FCRKSTIHGLNHVANSKSVCQRIFWLSICFSASVGLFINMYYLIEKFIERPVLTNI-LQDHAVFSYPDISFCFMNPIYFPPMNTSHFAFLMEKYQEYKHYVAVQE------------EFFKYHIKFGEFLFMKKNQTYTHPAWLAVISCNYLGLPCSHVNFIQRYLFP-FGACYTFNSTSVEASDAQFRQHMT-TNRELEIIIFKAVDIVPGTISDPFESVLMPSGMLFMIHDKETWPQ---VRESYVLDGYSQIDLKIINKVHLNIG-NRCRP---IKNKFSYYDVFMKTNTSVYGKYSDCVFQNVQQEVSRYCKCQWPKMQALSEFHNLPFCLDGH---LSLIEFGNCVSKAYTILDGGILDECYMD--------DCEHTTYETVISQSKFPAMIERKTQQKWLKILADLEKKEIEHFGKSDLYLRSLKSTNKYQVNLSEALNNKDWSLLDEEFVERNFMMIKVMPTSMFIDKVEETEEYPISRLLSDIGGCVGLWIGASLITIFEFLDLF 1701
            F   ++ HG++++A +++  +++ WL++   +   L   +Y  +  +   P  T+I +Q      +P ++ C +N   F     S F  +   +      + +QE            +F   H  F    F+K N  Y +   L  + C + G  CS  +F  +++F  +G C+TFN       + Q +  ++ + R L++++    D+     +D        +G++F+IH  +  PQ   +  S  +  ++++ ++ +  VH       C P   ++N  +Y         S YG   +C  +++Q    R C C             LPF L G+     L+E+ NCVS     ++   L  C M          CE T Y   +S S FP+       Q+  + LA                    K  N+ Q                 E++  N + I++  + +     ++ +   +  LL+D+GG +GL+ GASLITI E ++ F
Sbjct:   41 FAMSTSFHGIHNIAQNQNKVRKVIWLAVVLGSVSLLVWQIYSRLVNYFTWPTTTSIEVQYVEKIEFPAVTLCNLN--RFQTEAVSRFGIIFFLWDIVSKVLRLQEISANNTGSPETLDFVTNHQNFSITEFVKNNGFYLNNDTL--VHCEFFGKTCSPKDF--KHVFTEYGNCFTFNY----GENIQNKNKVSVSGRGLKLLL----DVHQEEFTDNPVPGFADAGVIFVIHSPKKEPQFDGLGLSSPVGMHARVTIRQLKTVHQEYPWGECNPNIKLRNFITY---------STYGCLKECKARHIQ----RLCGC-------------LPFLLPGNGVECDLLEYYNCVSPILDHIERKGL--CTMGTHNSSCPVSCEETEYPATVSYSTFPS-------QRATRFLA--------------------KKLNQSQ-----------------EYIRENLVNIEINYSDLNYKITQQQKAVSVPELLADVGGQLGLFCGASLITIIEIIEYF 467
[Close]
BLAST of acid-sensing ion channel 5 vs. UniProt/SwissProt
Match: sp|Q9R0W5|ASIC5_RAT (Acid-sensing ion channel 5 OS=Rattus norvegicus OX=10116 GN=Asic5 PE=1 SV=1)

HSP 1 Score: 90.1225 bits (222), Expect = 1.091e-17
Identity = 114/516 (22.09%), Postives = 212/516 (41.09%), Query Frame = 1 
Query:  262 FCRKSTIHGLNHVANSKSVCQRIFWLSICFSASVGLFINMYYLIEKFIERPVLTNI-LQDHAVFSYPDISFCFMNPIYFPPMNTSHFAFLMEKYQEYKHYVAVQE------------EFFKYHIKFGEFLFMKKNQTYTHPAWLAVISCNYLGLPCSHVNFIQRYLFP-FGACYTFNSTSVEASDAQFRQHMT-TNRELEIIIFKAVDIVPGTISDPFESVLMPSGMLFMIHDKETWPQ---VRESYVLDGYSQIDLKIINKVHLNIG-NRCRPIKNKFSYYDVFMK--TNTSVYGKYSDCVFQNVQQEVSRYCKCQWPKMQALSEFHNLPFCLDGH---LSLIEFGNCVSKAYTILDGGILDECYMDD--------CEHTTYETVISQSKFPAMIERKTQQKWLKILADLEKKEIEHFGKSDLYLRSLKSTNKYQVNLSEALNNKDWSLLDEEFVERNFMMIKVMPTSMFIDKVEETEEYPISRLLSDIGGCVGLWIGASLITIFEFLD-LFMDF 1710
            F   ++ HG++++A +++  +++ WLS+   +   L   +Y  +  +   P  T+I +Q      +P ++FC +N   F     S F  +   +      + +QE            +F   H  F    F+K N  Y +   L  + C + G  C   +F  +++F  +G C+TFN       + Q +  ++ + R L++++    D+     +D        +G++F+IH  +  PQ   +  S  +  ++++ ++ +  +H       C P        D+ ++  T  S YG   +C  +++Q    R C C             LPF L G+     L+++ NCVS     ++   L  C M          CE T Y   I+ S FP+       Q+  K LA                    K  N+ Q                 E++  N + I++  + +     ++ +   +  LL+D+GG +GL+ GASLITI E ++ LF  F
Sbjct:   41 FAISTSFHGIHNIAQNQNKVRKVIWLSVVLGSVSLLVWQIYSRLVNYFMWPTTTSIEVQYVEKIEFPAVTFCNLN--RFQTEAVSRFGIIFFLWDIVSKVLRLQEISGNNTGSPEALDFVASHRNFSITEFVKNNGFYLNHDTL--VHCEFFGKTCDPKDF--KHVFTEYGNCFTFNY----GENVQSKNKVSVSGRGLKLLL----DVHQEEFTDNPVPGFADAGVIFVIHSPKKEPQFDGLGLSSPVGMHARVTIRQLKTIHQEYPWGECNP--------DIKLRNFTTYSTYGCLKECKAKHIQ----RLCGC-------------LPFLLPGNGVECDLLKYYNCVSPILDHIERKGL--CTMGTHNSSCPVPCEETEYPATIAYSTFPS-------QRATKFLA--------------------KKLNQSQ-----------------EYIRENLVNIEINYSDLNYKITQQQKAVSVPELLADVGGQLGLFCGASLITIIEIIEYLFTSF 471
[Close]
BLAST of acid-sensing ion channel 5 vs. UniProt/SwissProt
Match: sp|Q708S6|ASI1C_DANRE (Acid-sensing ion channel 1C OS=Danio rerio OX=7955 GN=asic1c PE=1 SV=1)

HSP 1 Score: 80.4925 bits (197), Expect = 1.578e-14
Identity = 113/522 (21.65%), Postives = 205/522 (39.27%), Query Frame = 1 
Query:  262 FCRKSTIHGLNHVANSKSVCQRIFWLSICFSASVGLFINMYYLIEK---FIERPVLTNILQDHAV-FSYPDISFCFMNPIYFPPMNTSHF-------AFLMEKYQEYKHYVAVQE--EFFKYHIKFGEFLFMKKNQT-----YTHPAWLAVISCNYLGLPCSHVNFIQRYLFPFGACYTFNSTSVEASDAQFRQHMTTNRELEIIIFKAVDIVPGTISDPFESVLMPSGMLFMIHDKETWPQVRE-SYVLDGYSQIDLKIINKVHLNIG---NRCRPIKNKFSYYDVFMKTNTSVYGKYSDCVFQNVQQEVSRYCKCQWPKMQALSEFHNLPFCLDGHLSLIEFGNCVSKAYTILDGGILDECYMDD-CEHTTYETVISQSKFPAMIERKTQQKWLKILADLEKKEIEHFGKSDLYLRSLKSTNKYQVNLSEALNNKDWSLLDEEFVERNFMMIKVMPTSMFIDKVEETEEYPISRLLSDIGGCVGLWIGASLITIFEFLDLFMDFVETRMIPAKQTKPREH 1758
            F   ST+HG++H+     +  R F  ++ F  S+GL   MY  +++   + E P +T + +  A   ++P ++FC +N   F  +  +         A L E YQ    ++A  E     K    F  F   + N T       H     ++ C++ G  C  +NF   Y   +G CYTFNS  ++ +         T   LEI++    D       D  E+    +G+   IH ++  P + +  + +    Q  +    ++ L +      CR       Y+  +  T   +     DC  + + +     C C+   M   S             +  ++ +C   A   L     D C  D  C  T Y   +S  K P+                                   K++ KY   L++  N        E+++  N +++ +   ++  +K+E+ + Y ++ LL DIGG +GL+IGAS++TI E  D   + ++ +++ +   K R H
Sbjct:   23 FANNSTLHGMSHIFAYGHMTFRRFLWTLSFMGSLGLL--MYVCMDRVYYYFEFPHVTKLDEVAAPNLTFPAVTFCNLNEFRFSKITKNDLYHVGELLALLNENYQIANPHLADPEVLTLLKEKASFNGFKPKQFNMTDFYNRTGHDINEMLLQCSFRGEECFPLNFTTIYT-RYGKCYTFNS-GLDGNPLLTTLKGGTGNGLEIMLDIQQDEYLPVWGDTDETS-YEAGIKVQIHSQDEPPFIDQLGFGVAPGFQTFVSCQQQLLLYLPPPWGDCRSAPMDSEYFSTYSITACRI-----DCETRYLLEN----CNCRMVHMPGTSTV----------CTPEQYKDCADPALDFLVEKDNDYCVCDTPCNMTRYGKELSMVKIPS-----------------------------------KASAKY---LAKKFNKT------EQYITDNILVLDIFFEALNYEKIEQKKAYEVAGLLGDIGGQMGLFIGASVLTILEIFDYLYEVLKDKILGSVLRKRRPH 476
[Close]
BLAST of acid-sensing ion channel 5 vs. UniProt/SwissProt
Match: sp|Q9NY37|ASIC5_HUMAN (Acid-sensing ion channel 5 OS=Homo sapiens OX=9606 GN=ASIC5 PE=1 SV=1)

HSP 1 Score: 79.337 bits (194), Expect = 3.314e-14
Identity = 111/514 (21.60%), Postives = 204/514 (39.69%), Query Frame = 1 
Query:  262 FCRKSTIHGLNHVANSKSVCQRIFWLSICFSASVGLFINMYYLIEKFIERPVLTNI-LQDHAVFSYPDISFCFMNPIYFPPMNTSHFAFLMEKYQEYKHYVAVQE------------EFFKYHIKFGEFLFMKKNQTYTHPAWLAVISCNYLGLPCSHVNFIQRYLFPFGACYTFNSTSVEASDAQFRQHMTTNRELEIIIFKAVDIVPGTISDPFESVLMPSGMLFMIHDKETWPQVRESYVLDG---YSQIDLKIINKVHLNIG-NRCRP-IK-NKFSYYDVFMKTNTSVYGKYSDCVFQNVQQEVSRYCKCQWPKMQALSEFHNLPFCLDGH---LSLIEFGNCVSKAYTILDGGILDECYMD--------DCEHTTYETVISQSKFPAMIERKTQQKWLKILADLEKKEIEHFGKSDLYLRSLKSTNKYQVNLSEALNNKDWSLLDEEFVERNFMMIKVMPTSMFIDKVEETEEYPISRLLSDIGGCVGLWIGASLITIFEFLD-LFMDF 1710
            F   ++ HG++++  ++S  +R+ WL +   +   +   +Y  +  +   P  T+I +Q      +P ++FC +N   F     + F  +   +      + +QE            +F   H  F    F++    Y + + L  + C + G PCS  +F   +   +G C+TFN    E   A+ R+   + R L ++     ++     +D      + +G++F+IH  +  PQ     +L     ++++ ++ +  VH       C P IK   FS Y              S C+ +   Q + + C C             +PF L G+     L ++ +CVS     ++    D C +          CE   Y   IS S FP+       QK LK L+                 + L  + KY                    +  N + I++  + +     ++ +   +S LL+D+GG +GL+ GASLITI E ++ LF +F
Sbjct:   41 FAISTSFHGIHNIVQNRSKIRRVLWLVVVLGSVSLVTWQIYIRLLNYFTWPTTTSIEVQYVEKMEFPAVTFCNLN--RFQTDAVAKFGVIFFLWHIVSKVLHLQEITANSTGSREATDFAASHQNFSIVEFIRNKGFYLNNSTL--LDCEFFGKPCSPKDFAHVFT-EYGNCFTFNHG--ETLQAK-RKVSVSGRGLSLLF----NVNQEAFTDNPALGFVDAGIIFVIHSPKKVPQFDGLGLLSPVGMHARVTIRQVKTVHQEYPWGECNPNIKLQNFSSYST------------SGCLKECKAQHIKKQCGC-------------VPFLLPGYGIECDLQKYFSCVSPVLDHIE--FKDLCTVGTHNSSCPVSCEEIEYPATISYSSFPS-------QKALKYLS-----------------KKLNQSRKY--------------------IRENLVKIEINYSDLNYKITQQQKAVSVSELLADLGGQLGLFCGASLITIIEIIEYLFTNF 471
[Close]
BLAST of acid-sensing ion channel 5 vs. UniProt/SwissProt
Match: sp|Q22851|ASIC2_CAEEL (Degenerin-like protein asic-2 OS=Caenorhabditis elegans OX=6239 GN=asic-2 PE=3 SV=1)

HSP 1 Score: 64.3142 bits (155), Expect = 2.182e-9
Identity = 55/187 (29.41%), Postives = 88/187 (47.06%), Query Frame = 1 
Query:  262 FCRKSTIHGLNHVANSKSVCQRIFWLSICFSASVGLFI-NMYYLIEKFIERP--VLTNILQDHAVFSYPDISFCFMNPIYFPPMNT----SHFAFLMEKYQEYK---------HYVAVQEEFFKYHIKFGEFLFMKKN---QTYTHPAWLA----VISCNYLGLPCSHVNFIQRYLFP-FGACYTFN 750
            F   ST+  + HVAN+ +   RIFW++I F   +G+F   +Y LI KF   P  V T IL +  +F  P ++ C MNP  +  + +    S    LM  Y +              A  +E +    +  + L ++ N    T   PA       +  C++ G+PCS  +F  +++ P +GACY+FN
Sbjct:   13 FSNWSTVAVVPHVANANNKISRIFWIAI-FLFVLGMFAYELYILIAKFFSYPATVNTEILFEKQIF--PVVTVCNMNPYKYSVVKSNSAFSSVNTLMTTYSDATVGTFSTDKWGLYADNDETYDLDSRAADALVLEANLISDTAKVPALYTYADLIQDCSFAGIPCSESDFT-KFIDPVYGACYSFN 195
[Close]
BLAST of acid-sensing ion channel 5 vs. TrEMBL
Match: A0A0R3SIE1 (Uncharacterized protein OS=Hymenolepis diminuta OX=6216 GN=HDID_LOCUS4705 PE=3 SV=1)

HSP 1 Score: 414.461 bits (1064), Expect = 2.697e-132
Identity = 204/496 (41.13%), Postives = 311/496 (62.70%), Query Frame = 1 
Query:  256 LTFCRKSTIHGLNHVANSKSVCQRIFWLSICFSASVGLFINMYYLIEKFIERPVLTNILQDHAVFSYPDISFCFMNPIYFPPMNTSHFAFLMEKYQEYKHYVAVQEEFFKYHIKFGEFLFMKKNQTYTHPAWLAVISCNYLGLPCSHVNFIQRYLFPFGACYTFNSTSVEASDAQFRQHMTTNR------ELEIIIFKAVDIVPGTISDPFESVLMPSGMLFMIHDKETWPQVRESYVLDGYSQIDLKIINKVHLNIGNRCRPIKNKFSYYDVFMKTNTSVYGKYSDCVFQNVQQEVSRYCKCQWPKMQALSEFHNLPFCLDGHLSLIEFGNCVSKAYTILDGGILDECYMDDCEHTTYETVISQSKFPAMIERKTQQKWLKILADLEKKEIEHF-GKSDLYLRSLKSTNKYQVNLS--EALNNKDWSLLDEEFVERNFMMIKVMPTSMFIDKVEETEEYPISRLLSDIGGCVGLWIGASLITIFEFLDLFMDFVE 1716
            L F R+ST+HGLNH+A +++  +R+FWL I  +A VG F NM++LIEK+I+ PVLTN+L D   F YPD++FC +NPIYFPP  T+ F  ++   +++K +         + ++  ++LF+++N  Y HP WL ++ C Y+  PCS+ +F ++ L+P+GACYTFN+T +   +   R+ +T NR      + +II++KA+D+      DP  SV +PSG+L MIH+  T+P +  S ++D  +QI+L++    HL    +C P +   SY +     + +     SDC+   VQ  ++  C CQ   M  +  ++NLPFC    L+     +C S     +D      C+ D CEH T + V+  +KFPA+ ER T Q WL++LA LE++E   + GKSD+   +L +      NL+  +   + + SLL+ +FV RNFMM++++P S+F+D+VEETEEYP SRLLSDIGGCVGLWIGASLIT+FEF DL +DF++
Sbjct:   80 LRFSRRSTMHGLNHLAQARTAQRRLFWLCISIAALVGFFFNMFFLIEKYIQVPVLTNVLHDSDNFIYPDVTFCNINPIYFPPKETAEFKRMIAAIEKFKKFKKSTHPHV-HRLELADYLFVERNTFYVHPKWLTIVECQYMQTPCSYKHFDEKILWPYGACYTFNATKM--LNNMTREIITRNRFNRFRPDFKIIVYKALDMPEEYRMDPHGSVNVPSGILLMIHEPGTYPHIGHSSIVDECAQIELRMTYVKHLAKLGKCVPEREHISYVNTATNESQNFLSSQSDCLDAAVQTALAENCGCQMHTMPVMYRYNNLPFCFSDSLNFSFIESCFSNVSNAVDR---QHCFRDVCEHFTIDRVVVHAKFPAIAERHTYQNWLRLLARLEEREKAQYRGKSDIAKLALNADFTANPNLTIKDIFASGNTSLLNLDFVNRNFMMLRIVPASLFMDRVEETEEYPFSRLLSDIGGCVGLWIGASLITLFEFADLILDFMD 569
[Close]
BLAST of acid-sensing ion channel 5 vs. TrEMBL
Match: A0A564Z6I1 (Uncharacterized protein OS=Hymenolepis diminuta OX=6216 GN=WMSIL1_LOCUS12764 PE=3 SV=1)

HSP 1 Score: 414.461 bits (1064), Expect = 2.756e-132
Identity = 204/496 (41.13%), Postives = 311/496 (62.70%), Query Frame = 1 
Query:  256 LTFCRKSTIHGLNHVANSKSVCQRIFWLSICFSASVGLFINMYYLIEKFIERPVLTNILQDHAVFSYPDISFCFMNPIYFPPMNTSHFAFLMEKYQEYKHYVAVQEEFFKYHIKFGEFLFMKKNQTYTHPAWLAVISCNYLGLPCSHVNFIQRYLFPFGACYTFNSTSVEASDAQFRQHMTTNR------ELEIIIFKAVDIVPGTISDPFESVLMPSGMLFMIHDKETWPQVRESYVLDGYSQIDLKIINKVHLNIGNRCRPIKNKFSYYDVFMKTNTSVYGKYSDCVFQNVQQEVSRYCKCQWPKMQALSEFHNLPFCLDGHLSLIEFGNCVSKAYTILDGGILDECYMDDCEHTTYETVISQSKFPAMIERKTQQKWLKILADLEKKEIEHF-GKSDLYLRSLKSTNKYQVNLS--EALNNKDWSLLDEEFVERNFMMIKVMPTSMFIDKVEETEEYPISRLLSDIGGCVGLWIGASLITIFEFLDLFMDFVE 1716
            L F R+ST+HGLNH+A +++  +R+FWL I  +A VG F NM++LIEK+I+ PVLTN+L D   F YPD++FC +NPIYFPP  T+ F  ++   +++K +         + ++  ++LF+++N  Y HP WL ++ C Y+  PCS+ +F ++ L+P+GACYTFN+T +   +   R+ +T NR      + +II++KA+D+      DP  SV +PSG+L MIH+  T+P +  S ++D  +QI+L++    HL    +C P +   SY +     + +     SDC+   VQ  ++  C CQ   M  +  ++NLPFC    L+     +C S     +D      C+ D CEH T + V+  +KFPA+ ER T Q WL++LA LE++E   + GKSD+   +L +      NL+  +   + + SLL+ +FV RNFMM++++P S+F+D+VEETEEYP SRLLSDIGGCVGLWIGASLIT+FEF DL +DF++
Sbjct:   80 LRFSRRSTMHGLNHLAQARTAQRRLFWLCISIAALVGFFFNMFFLIEKYIQVPVLTNVLHDSDNFIYPDVTFCNINPIYFPPKETAEFKRMIAAIEKFKKFKKSTHPHV-HRLELADYLFVERNTFYVHPKWLTIVECQYMQTPCSYKHFDEKILWPYGACYTFNATKM--LNNMTREIITRNRFNRFRPDFKIIVYKALDMPEEYRMDPHGSVNVPSGILLMIHEPGTYPHIGHSSIVDECAQIELRMTYVKHLAKLGKCVPEREHISYVNTATNESQNFLSSQSDCLDAAVQTALAENCGCQMHTMPVMYRYNNLPFCFSDSLNFSFIESCFSNVSNAVDR---QHCFRDVCEHFTIDRVVVHAKFPAIAERHTYQNWLRLLARLEEREKAQYRGKSDIAKLALNADFTANPNLTIKDIFASGNTSLLNLDFVNRNFMMLRIVPASLFMDRVEETEEYPFSRLLSDIGGCVGLWIGASLITLFEFADLILDFMD 569
[Close]
BLAST of acid-sensing ion channel 5 vs. TrEMBL
Match: A0A183SCX1 (Uncharacterized protein OS=Schistocephalus solidus OX=70667 GN=SSLN_LOCUS2069 PE=3 SV=1)

HSP 1 Score: 409.068 bits (1050), Expect = 9.733e-132
Identity = 202/488 (41.39%), Postives = 313/488 (64.14%), Query Frame = 1 
Query:  256 LTFCRKSTIHGLNHVANSKSVCQRIFWLSICFSASVGLFINMYYLIEKFIERPVLTNILQDHAVFSYPDISFCFMNPIYFPPMNTSHFAFLMEKYQEYKHYVAVQEEFFKYHIKFGEFLFMKKNQTYTHPAWLAVISCNYLGLPCSHVNFIQRYLFPFGACYTFNSTSVEAS-DAQFRQHMTTNR---ELEIIIFKAVDIVPGTISDPFESVLMPSGMLFMIHDKETWPQVRESYVLDGYSQIDLKIINKVHLNIGNRCRPIKNKFSYYDVFMKTNTSVYGKYSDCVFQNVQQEVSRYCKCQWPKMQALSEFHNLPFCLDGHLSLIEFGNCVSKAYTILDGGILDECYMDDCEHTTYETVISQSKFPAMIERKTQQKWLKILADLEKKEIEHF-GKSDLYLRSLKSTNKYQVNLSEALNNKDWSLLDEEFVERNFMMIKVMPTSMFIDKVEETEEYPISRLLSDIGGCVGLWIGASLITIFEFLDLFM 1704
            L F R+ST+HGLNH+A +++  +R+FWL I  ++S G F N+++L+EK+I+ PVLTN+L D   F +PD++FC +NPIYFPP  T  F  + E    ++ +      F K  +   ++LF+K+N  Y HP WL ++ C+Y+  PCS  +F ++ ++P+GACYTFN+T +  +   +       NR   +L II++KA++   G   DP +S  +P G+L MIH+  T+P +  S ++D  +Q++LK+ +  HL    +C P++++ +Y +V    + +     SDC+   VQ  +++YC CQ   M  + E+H+ PFC  G L       C +KA   +D      C++D CEH T + VI+ +KFPA+ +R T+Q WL++LADLE +E++ + G+SDL   +LK      + L+EA   +   LL+ +FV RNFMM++V+P S+F+D+VEETEEYP SRLLSDIGGCVGLWIGASLIT+FE L++F+
Sbjct:   78 LRFSRRSTMHGLNHLAQARTAQRRLFWLCISLASSFGFFFNLFFLMEKYIQVPVLTNVLHDSDNFIFPDVTFCNVNPIYFPPNGTPEFERIKENIHAFEDFKRSSNPFAK-RLALADYLFIKRNTYYVHPKWLTIVECSYMQTPCSSEHFDEKIIWPYGACYTFNATRMPHNMSREISTRTRYNRFRPDLRIIVYKALEFPEGYRFDPHDSFQVPPGVLLMIHEPGTYPHIGHSGIVDECTQVELKMTSVTHLAKLGKCIPMRSRIAYVNVASNESQTFLSSQSDCLDAEVQSALAKYCGCQMHTMPIMYEYHHQPFCFSGALEPSFLETCFNKATASVDR---KHCFLDVCEHYTIDRVIAHTKFPAVEDRHTEQHWLQLLADLEDRELKQYSGRSDLAKMALKDVPGGNITLAEAAKKRQIDLLNIDFVNRNFMMLRVVPDSLFMDRVEETEEYPFSRLLSDIGGCVGLWIGASLITLFE-LEIFL 560
[Close]
BLAST of acid-sensing ion channel 5 vs. TrEMBL
Match: A0A3P7LUS4 (Uncharacterized protein OS=Dibothriocephalus latus OX=60516 GN=DILT_LOCUS5772 PE=3 SV=1)

HSP 1 Score: 405.601 bits (1041), Expect = 3.760e-129
Identity = 215/536 (40.11%), Postives = 335/536 (62.50%), Query Frame = 1 
Query:  202 GMTRNPKKIIS-YRTLSIG---LTFCRKSTIHGLNHVANSKSVCQRIFWLSICFSASVGLFINMYYLIEKFIERPVLTNILQDHAVFSYPDISFCFMNPIYFPPMNTSHFAFLMEKYQEYKHYVAVQEEFFKYHIKFGEFLFMKKNQTYTHPAWLAVISCNYLGLPCSHVNFIQRYLFPFGACYTFNSTSVEASDAQFRQHMTTNR------ELEIIIFKAVDIVPGTISDPFESVLMPSGMLFMIHDKETWPQVRESYVLDGYSQIDLKIINKVHLNIGNRCRPIKNKFSYYDVFMKTNTSVYGKYSDCVFQNVQQEVSRYCKCQWPKMQALSEFHNLPFCLDGHLSLIEFGNCVSKAYTILDGGILDECYMDDCEHTTYETVISQSKFPAMIERKTQQKWLKILADLEKKEIEHFG-KSDLYLRSLKSTNK---YQVNLSEALNNKDWSLLDEEFVERNFMMIKVMPTSMFIDKVEETEEYPISRLLSDIGGCVGLWIGASLITIFEFLDLFMDFVETRMIPAKQTKPREHLKN 1767
            G  R P K  + Y   ++G   L F R+ST+HGLNH+A +++  +R+FWL I  ++S G F N+++L+EK+++ PVLTN+L D   F +PD++FC +NPI+FPP  T  F  + E  +E++ +      F +  +   ++LF+K+N  Y HP WL ++ C+Y+  PCS  +F ++ ++P+GACYTFN+T +  +    R+  T  R      +L +I++KA++   G   DP +S  +P G+L MIH+  T+P +  S ++D  +Q++LK+ +  HL    +C PI+++ SY +V    + +     SDC+   VQ  +++YC CQ   M  + E+H  PFC  G L      NC + A   +D      C++D CEH T + VI+ +KFPA+ +R T+  WL++LA LE +E  H+G KSDL   +LK+ ++       L+EA+N +   LL+ +FV RNFMM++V+P S+F+D+VEETEEYP SRLLSDIGGCVGLWIGASLIT+FE +DL +DF++   I  + T  ++HL  
Sbjct:   52 GSFRRPSKPSAIYLVAALGASCLRFSRRSTMHGLNHLAQARTAQRRLFWLCISLASSFGFFFNLFFLMEKYLQMPVLTNVLHDSDNFIFPDVTFCNVNPIHFPPNGTPEFERIKENIREFEDFKRGPNPFAQ-RLALADYLFIKRNTYYVHPKWLTIVECSYMQTPCSSEHFDEKIIWPYGACYTFNATRMPHN--MTREISTRTRYNRFRPDLRVIVYKALEFPEGYRFDPHDSFQVPPGVLLMIHEPGTYPHIGHSGIVDECTQVELKMTSVTHLAKLGKCIPIRSRISYVNVAKNESQTFLSSQSDCLDAEVQSALAKYCGCQMHTMPIMYEYHYQPFCFSGALDPTFLENCFNNATASVD---RKHCFLDVCEHYTIDQVIAHTKFPAIEDRHTELHWLQLLARLEARERNHYGGKSDLAKLALKNASRDGGGNWTLAEAVNQRQIDLLNIDFVNRNFMMLRVVPASLFMDRVEETEEYPFSRLLSDIGGCVGLWIGASLITLFELVDLLLDFLDLGGIGGQNTNHQQHLSG 581
[Close]
BLAST of acid-sensing ion channel 5 vs. TrEMBL
Match: A0A0R3TJX9 (Uncharacterized protein OS=Rodentolepis nana OX=102285 GN=HNAJ_LOCUS7422 PE=3 SV=1)

HSP 1 Score: 391.734 bits (1005), Expect = 1.858e-123
Identity = 204/499 (40.88%), Postives = 310/499 (62.12%), Query Frame = 1 
Query:  256 LTFCRKSTIHGLNHVANSKSVCQRIFWLSICFSASVGLFINMYYLIEKFIERPVLTNILQDHAVFSYPDISFCFMNPIYFPPMNTSHFAFL---MEKYQEYKHYVAVQEEFFKYHIKFGEFLFMKKNQTYTHPAWLAVISCNYLGLPCSHVNFIQRYLFPFGACYTFNSTSVEASDAQFRQHMTTNR------ELEIIIFKAVDIVPGTISDPFESVLMPSGMLFMIHDKETWPQVRESYVLDGYSQIDLKIINKVHLNIGNRCRPIKNKFSYYDVFMKTNTSVYGKYSDCVFQNVQQEVSRYCKCQWPKMQALSEFHNLPFCLDGHLSLIEFGNCVSKAYTILDGGILDECYMDDCEHTTYETVISQSKFPAMIERKTQQKWLKILADLEKKEIEHF-GKSDLYLRSLKSTNKYQVNLS--EALNNKDWSLLDEEFVERNFMMIKVMPTSMFIDKVEETEEYPISRLLSDIGGCVGLWIGASLITIFEFLDLFMDFVE 1716
            L F R+ST+HGLNH++ +++  +R+FWL I  +A  G F NM++L+EK+++ PVLTN+L D   F YPD++FC +NPIYFPP  T+ F  +   +EK++E+K           + ++  ++LF+++N  Y HP WL ++ C Y+  PCS+ +F ++ L+P+GACYTFN+T +   +   R+ +T NR      + +II++KA+D+      DP  SV +PSG+L MIH+  T+P +  S ++D  +QI+L++    HL    +C P +   SY +     +        DC+   VQ  ++  C CQ   M  + ++H+LPFC    L+     NC S     +D      C+ D CEH T + V++ +KFPA+ ER T   WL +LA LE++E   + GKSD+   +L +      NL+  E L + + SLL+ +FV RNFMM++++P S+F+D+VEETEEYP SRLLSDIGGCVGLWIGASLIT+FEF DL +D V+
Sbjct:   82 LRFSRRSTMHGLNHLSQARTAQRRLFWLCISIAALFGFFFNMFFLVEKYVQVPVLTNVLHDSDNFIYPDVTFCTINPIYFPPEGTTEFERMSSAIEKFKEFKR----SNHPHVHRLELADYLFVERNTYYVHPKWLTIVECQYMQTPCSYKHFDEKILWPYGACYTFNATKM--LNNMTREIITRNRFNRFRPDFKIIVYKALDMPEKFRMDPHGSVNVPSGVLLMIHEPGTYPHIGHSSIVDECTQIELRMTYVKHLAKLGKCVPEREYISYVNTATNKSQIFLSSQPDCLDAAVQTALAENCGCQMHTMPVMYKYHHLPFCFSDALNFTFIENCFSNVANTVDR---KHCFRDVCEHFTIDRVVAHAKFPAIEERHTYYNWLHLLARLEEREEAQYKGKSDIAKLALNADFTVNPNLTIKEVLVSGNTSLLNLDFVNRNFMMLRIVPASLFMDRVEETEEYPFSRLLSDIGGCVGLWIGASLITLFEFADLILDCVD 571
[Close]
BLAST of acid-sensing ion channel 5 vs. Ensembl Cavefish
Match: asic4a (acid-sensing ion channel 4 [Source:NCBI gene;Acc:103040152])

HSP 1 Score: 57.3806 bits (137), Expect = 3.358e-8
Identity = 27/86 (31.40%), Postives = 51/86 (59.30%), Query Frame = 1 
Query: 1522 EEFVERNFMMIKVMPTSMFIDKVEETEEYPISRLLSDIGGCVGLWIGASLITIFEFLDLFMDFVETRMI----PAKQTKPREHLKN 1767
            E+++  NF+++ +   ++  + +E+ + Y ++ LL DIGG +GL+IGAS++T+ E LD   + V+ R+     P K   P    K+
Sbjct:  403 EDYIRDNFLVLDIFFEALNYETIEQKKAYDVAGLLGDIGGQMGLFIGASILTVLEILDYIYEVVKRRLQRALKPQKDQNPPSQQKS 488
[Close]
BLAST of acid-sensing ion channel 5 vs. Ensembl Cavefish
Match: asic4b (acid-sensing ion channel 4 [Source:NCBI gene;Acc:103044180])

HSP 1 Score: 57.3806 bits (137), Expect = 3.389e-8
Identity = 24/68 (35.29%), Postives = 46/68 (67.65%), Query Frame = 1 
Query: 1522 EEFVERNFMMIKVMPTSMFIDKVEETEEYPISRLLSDIGGCVGLWIGASLITIFEFLDLFMDFVETRM 1725
            E+++  NF+++ +   ++  + +E+ + Y I+ LL DIGG +GL+IGAS++TI E LD   + ++ R+
Sbjct:  407 EDYIRDNFLILDIYFEALNYETIEQKKAYDIAGLLGDIGGQMGLFIGASILTILEILDYIYEVIKHRI 474
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BLAST of acid-sensing ion channel 5 vs. Ensembl Cavefish
Match: asic1c (acid-sensing ion channel 1C-like [Source:NCBI gene;Acc:103034544])

HSP 1 Score: 54.6842 bits (130), Expect = 2.101e-7
Identity = 24/86 (27.91%), Postives = 52/86 (60.47%), Query Frame = 1 
Query: 1522 EEFVERNFMMIKVMPTSMFIDKVEETEEYPISRLLSDIGGCVGLWIGASLITIFEFLDLFMDFVETRMIP--AKQTKPREHLKNTL 1773
            E+++  N +++ +   ++  +K+E+ + Y ++ LL DIGG +GL+IGAS++TI E  D   +  + +++    ++ +PR    + L
Sbjct:  398 EQYIGDNILVLDIFFEALNYEKIEQKKAYEVAGLLGDIGGQMGLFIGASVLTILEIFDYLYEVFKDKVLGYFLRKGRPRRSASDNL 483
[Close]
BLAST of acid-sensing ion channel 5 vs. Ensembl Cavefish
Match: asic1c (acid-sensing ion channel 1C-like [Source:NCBI gene;Acc:103034544])

HSP 1 Score: 54.6842 bits (130), Expect = 2.218e-7
Identity = 24/86 (27.91%), Postives = 52/86 (60.47%), Query Frame = 1 
Query: 1522 EEFVERNFMMIKVMPTSMFIDKVEETEEYPISRLLSDIGGCVGLWIGASLITIFEFLDLFMDFVETRMIP--AKQTKPREHLKNTL 1773
            E+++  N +++ +   ++  +K+E+ + Y ++ LL DIGG +GL+IGAS++TI E  D   +  + +++    ++ +PR    + L
Sbjct:  398 EQYIGDNILVLDIFFEALNYEKIEQKKAYEVAGLLGDIGGQMGLFIGASVLTILEIFDYLYEVFKDKVLGYFLRKGRPRRSASDNL 483
[Close]
BLAST of acid-sensing ion channel 5 vs. Ensembl Cavefish
Match: asic1c (acid-sensing ion channel 1C-like [Source:NCBI gene;Acc:103034544])

HSP 1 Score: 53.9138 bits (128), Expect = 4.711e-7
Identity = 24/86 (27.91%), Postives = 52/86 (60.47%), Query Frame = 1 
Query: 1522 EEFVERNFMMIKVMPTSMFIDKVEETEEYPISRLLSDIGGCVGLWIGASLITIFEFLDLFMDFVETRMIP--AKQTKPREHLKNTL 1773
            E+++  N +++ +   ++  +K+E+ + Y ++ LL DIGG +GL+IGAS++TI E  D   +  + +++    ++ +PR    + L
Sbjct:  415 EQYIGDNILVLDIFFEALNYEKIEQKKAYEVAGLLGDIGGQMGLFIGASVLTILEIFDYLYEVFKDKVLGYFLRKGRPRRSASDNL 500
[Close]
BLAST of acid-sensing ion channel 5 vs. Ensembl Sea Lamprey
Match: ASIC5 (acid sensing ion channel subunit family member 5 [Source:HGNC Symbol;Acc:HGNC:17537])

HSP 1 Score: 50.447 bits (119), Expect = 8.425e-7
Identity = 60/281 (21.35%), Postives = 109/281 (38.79%), Query Frame = 1 
Query:  892 GMLFMIHDKETWPQVRESYVLDGYSQIDLKIINKVHLNIGNRCRPIKNKFSYYDVFMKTNTSVYGKYS--DCVFQNVQQEVSRYCKCQWPKMQALSEFHNLPFCLDGHL---SLIEFGNCVSKAYTIL-------DGGILDECYMDDCEHTTYETVISQSKFPAMIERKTQQKWLKILADLEKKEIEHFGKSDLYLRSLKSTNKYQVNLSEALNNKDWSLLDEEFVERNFMMIKVMPTSMFIDKVEETEEYPISRLLSDIGGCVGLWIGASLITIFEFLDL 1698
            G+  ++HD +  PQV           + + +  + ++++    + I  ++ + D            YS   C+ +     V R C C+             PF   G +   SL +  +C   A  I         G  L +C +  C H  + + +S + FP                                  SL++  +Y+ +L       ++SL+   ++  N + I V  T +    +++ +  P S LLSDIGG +GL++GAS+ITI E L+ 
Sbjct:  235 GIRLVVHDPDEPPQVEAL-------GLSIGVGTQAYVSV-QHTKSINQQYPWGDCDPSKKLQSPAPYSMARCLQECEADLVERICGCK-------------PFNFPGDIKECSLYQHYHCARDALVIFLAQGMCTGGSHLSQCPVP-CLHKNFPSSVSYATFP----------------------------------SLQAAQRYERSL-------NYSLV---YMRENLLSIDVAYTDLNYALIQQQKTLPESVLLSDIGGQLGLFVGASVITIIEVLEF 449
[Close]
BLAST of acid-sensing ion channel 5 vs. Ensembl Sea Lamprey
Match: asic1a (acid-sensing (proton-gated) ion channel 1a [Source:NCBI gene;Acc:791696])

HSP 1 Score: 48.1358 bits (113), Expect = 4.819e-6
Identity = 21/85 (24.71%), Postives = 51/85 (60.00%), Query Frame = 1 
Query: 1522 EEFVERNFMMIKVM-PTSMFIDKVEETEEYPISRLLSDIGGCVGLWIGASLITIFEFLDLFMDFVETRMIPAKQTKPREHLKNTL 1773
            E+++  N +++ +    ++  + +E+ + Y ++ LL DIGG +GL+IGAS++TI E  D   + ++ ++   ++   ++  +N +
Sbjct:  412 EDYIRENVLVLDIFFEAALNYETIEQKKAYEVAGLLGDIGGQMGLFIGASILTILEIFDYLYEVLKDKVCKCRKKHNKKRSENMV 496
[Close]
BLAST of acid-sensing ion channel 5 vs. Ensembl Sea Lamprey
Match: ASIC5 (acid sensing ion channel subunit family member 5 [Source:HGNC Symbol;Acc:HGNC:17537])

HSP 1 Score: 48.1358 bits (113), Expect = 5.079e-6
Identity = 29/84 (34.52%), Postives = 50/84 (59.52%), Query Frame = 1 
Query: 1447 SLKSTNKYQVNLSEALNNKDWSLLDEEFVERNFMMIKVMPTSMFIDKVEETEEYPISRLLSDIGGCVGLWIGASLITIFEFLDL 1698
            SL++  +Y+ +L       ++SL+   ++  N + I V  T +    +++ +  P S LLSDIGG +GL++GAS+ITI E L+ 
Sbjct:  366 SLQAAQRYERSL-------NYSLV---YMRENLLSIDVAYTDLNYALIQQQKTLPESVLLSDIGGQLGLFVGASVITIIEVLEF 439
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BLAST of acid-sensing ion channel 5 vs. Ensembl Nematostella
Match: EDO49452 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RGQ6])

HSP 1 Score: 83.5741 bits (205), Expect = 4.450e-17
Identity = 114/497 (22.94%), Postives = 197/497 (39.64%), Query Frame = 1 
Query:  262 FCRKSTIHGLNHVANSKSVCQRIFWLSICFSASVGLFINMYYLIEKFIERPVLTNI-LQDHAVFSYPDISFCFMNPIYFPPMNTSHFAFLMEKYQEYKHYVA--------VQEEFFKYHIKFGE----FLFMKKNQTYTHPAWLAVISCNYLGLPCSHVNFIQRYLFPFGACYTFNSTSVEASDAQFRQHMTTNRELEIIIFKAVDIVPGTISDPFESVLMPSGMLFMIHDKETWPQVRESYVLDGYSQIDLKIINKVHLNIGNRCRPIKNKFSYYDVFMK-TNTSVYGKY--SDCVFQNVQQEVSRYCKCQWPKMQALSEFHNLPFCLDGHLSLIEFGNCVSKAY-TILDGGILDECYMDDCEHTTYETVISQSKFPAMIERKTQQKWLKILADLEKKEIEHFGKSDLYLRSLKSTNKYQVNLSEALNNKDWSLLDEEFVERNFMMIKVMPTSMFIDKVEETEEYPISRLLSDIGGCVGLWIGASLITIFEFLDLF 1701
            F    T+HG   V       +++ WL+I   A   L +     I+K+ + P+ T++ ++      +P ++ C  N   +  +N +    + EK +   + +         + E FF +   FGE    F F +  +T+ H     +  C +   PC   NF    +  FG CYTFNS  ++       Q    +  L + +    D   G++ D        SG   M+HD+E  P + E         + + I    H   G R   + N  + +    +      + KY  S C+ +     V + CKC+   ++  +     P C        E  NCV  A  T +   +  +     CE T Y+T +S ++ PA       + + ++LA   +K I                            NKD   +   ++  NF+ + V    M +  +++ + Y    L  DIGG VGL++GAS++T+ EFLDL 
Sbjct:    5 FLHTLTLHGFRFVFERGPTIRKVLWLAILLFAVGMLMMQSKKSIQKYFDHPITTSVQVEFLEEIQFPAVTICNFNLFPYYLINGT----IGEKVKTAPNLLILFFFSRPLLSESFF-FEKDFGELDEKFDFAEFVRTHGHRIDHMIKKCRWKSQPCGPENFTA-VITEFGLCYTFNS-GMKGHPLLKVQRAGVDYALRLQLSVQQDQYYGSLRD-------SSGFKVMVHDQEEPPLINE---------LGIAIQPGTHTFCGLRKEEMHNLPAPFKTACRDMQLEGFKKYTKSACLLKCRADYVMKMCKCRSYDLKGPA-----PPC-----QPREVKNCVWPAMGTCMFKQMTVQVCPVPCEITKYQTQLSYAQTPA-------KHFSEVLA--RRKHI----------------------------NKD---VMRHYLRDNFLELDVYFEEMQVTLIQQRQAYDQESLFGDIGGQVGLFLGASILTVLEFLDLL 428
[Close]
BLAST of acid-sensing ion channel 5 vs. Ensembl Nematostella
Match: EDO39413 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SA77])

HSP 1 Score: 73.559 bits (179), Expect = 1.133e-13
Identity = 110/508 (21.65%), Postives = 195/508 (38.39%), Query Frame = 1 
Query:  220 KKIISYRTLSIGLTFCRKSTIHGLNHVANSKSVCQRIFWLSICFSASVGLFINMYYLIEKFIERPVLT-NILQDHAVFSYPDISFCFMNPIYFPPMNTSHFAFLMEKYQEYK-HYVAVQEEFFKYHIKFGEFLFMKKNQTYTHPAWLAVISCNYLGLPCSHVNFIQRYLFPFGACYTFNSTSVEASDAQFRQHMTTNRELEIIIFKAVDIVPGTISDPFESVLMPSGMLFMIHDKETWPQVRESY--VLDG-YSQIDLKIINK----------VHLNIGNRCRPIKNKFSYYDVFMKTNTSVYGKYSDCVFQNVQQEVSRYCKCQWPKMQALSEFHNLPFCLDGHLSLIEFGNCVSKAYTILDGGILDECYMDDCEHTTYETVISQSKFPAMIERKTQQKWLKILADLEKKEIEHFGKSDLYLRSLKSTNKYQVNLSEALNNKDWSLLDEEFVERNFMMIKVMPTSMFIDKVEETEEYPISRLLSDIGGCVGLWIGASLITIFEFLDL 1698
            K+  S +   IG  F   +T+HGL+ +       ++I W  +   A+VGL I +   + K     + T           +P I+ C  N +    +  S     +++  E +  ++          I     +     Q   H     V  C ++   C + +         G CYTFNS  V  +      H  +   L +     +D  P     P+      +G    +HD++  P + E    +  G Y++I +K   K              I ++   + + +S      K   S    Y +C+ +   Q +   C+C+   M  L E    P+C     +  E  +C+ + +        D C +  CE TT+ + IS + FP+      Q  W   L  L                    T  Y +NL+  L+  +  +  E FV + F M+K+   ++  +   +   Y +S L +D+GG +GL++G S++TI EF+DL
Sbjct:   39 KQADSAKNTLIG-NFASYTTLHGLHFLFQPIPRARKIIWGIMLVIATVGLSIQIGNGLVKVYSYNIFTAKTFVRPESLPFPAITICNQNMLRKTAILGSAGQRYLDQLDELRARFIGEDMNVTSERINMDAIV-----QKSGHQLEKMVYECRFVRDKCDNKSIKVFTSEKRGLCYTFNS-GVNGTPLLNVSHSGSEYSLSL----RLDAEPTEYYGPYS--YDGTGFKIAVHDQKVLPDIEEDAYDISPGFYTKITMKRAQKQTKQSCTDVVTAYVINSQTLFLPSPYSSGCGSRKLQFSQEYSYKNCIRECHTQLMIGRCRCRAIGM-TLQENDTTPYC-----TTREVQDCIMRVHERSSRQRCD-CPVP-CEMTTFTSRISLAYFPS------QHVWETFLPFL--------------------TTAYDLNLT-GLSPDELDMKAEHFVRKRFAMVKIFYETLRTEMYHQRPAYEMSDLFADVGGNMGLFLGCSMLTIAEFIDL 498
[Close]
BLAST of acid-sensing ion channel 5 vs. Ensembl Nematostella
Match: EDO39446 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SA83])

HSP 1 Score: 62.7734 bits (151), Expect = 2.372e-10
Identity = 114/512 (22.27%), Postives = 201/512 (39.26%), Query Frame = 1 
Query:  214 NPKKIISYRTLSIGLTFCRKSTIHGLNHVANSKSVCQRIFWLSICFSASVGLFINMYYLIEKFIERPVLTNI-LQDHAVFSYPDISFCFMNPIYFPPM---NTSHFAFLMEKYQEYKHYVAVQEEFFKYHIKFGEFLFMKKNQTYTHPAWLAVISCNYLG-LPCSHVNFIQRYLFPFGACYTFNSTSVEASDAQFRQHMTT-NRELEIIIFKAVDIVPGTISDPFESVLMPSGMLFMIHDKETWPQVRESYVLDGYSQIDLKIINKVHLNIGNRCRPIKNKFSYYDVFMKTNTSVYGKYSDCVFQNVQQEVSRYCKCQWPKMQALSEFHNLPFCLDGHLSLIEFGNCVSKAYTILDGGILDECYMD-DCEHTTYETVISQSKFPA--MIERKTQQKWLKILADLEKKEIEHFGKSDLYLRSLKSTNKYQVNLSEALNNKDWSLLDEEFVERNFMMIKVMPTSMFIDKVEETEEYPISRLLSDIGGCVGLWIGASLITIFEFLDLFMDFVETR 1722
            NP + +     S+   F   +T+HG +   +S +  ++I W+ +    SV L   + Y  ++ +E   +  +  ++    ++P IS C  N +    +   +   +  L+++ +E   + A+ + F        +F   K    Y     LA+ SC+Y   L C+  +F     F +G CYTFNS   E++   F  H T     L I +    D  P      + S    +G   ++HD+  +P V +     G+     +I      N+    + I +  S Y+     +T+ Y   S C+ Q     V + C C    M    E  + P+C     S  +   CV   YT       + C     C    ++  +S   +P     E  + ++ L I A+                     T K+Q                 E+  R  + + V    +  +  +E E Y IS L  D GG +GL++G S++TI EF+DL + ++  R
Sbjct:   11 NPSESVEVPRESLLEAFSSYTTLHGFHFALSSTNRVRQIIWILLLILTSVVLIYQLAYSTQRVLEYASMVQVETRNEDSITFPAISICSNNMMQKSKILGKDAQRYLDLLDQKKE-DQWDAISQSFSP------DFDIEKAVHQYGLNLSLAMKSCHYGRYLKCNPSHFTTFKEFRYGLCYTFNSGKRESA---FISHDTGPTSGLSITL----DAQPEEYYSLYSST--GTGFRVIVHDQSEFPWVEK----HGW-----EIPPGFSTNVRLARKEISSLESPYNSNCSRDTN-YASQSYCLVQCYSDMVVKRCGCHMLGM--TEETGHTPWC-----SPQQIKACV---YTTSRRFQPNMCSCPVRCSRVEFDVQLSSLYYPPDNFWETISNERSLTIYAN--------------------DTKKFQ-----------------EWYRRRVIQLNVFYKELTTEVRKEKEAYTISDLAGDFGGNMGLFLGCSILTIAEFIDLLVVYLVHR 449
[Close]
BLAST of acid-sensing ion channel 5 vs. Ensembl Nematostella
Match: EDO42137 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S2F2])

HSP 1 Score: 60.4622 bits (145), Expect = 1.380e-9
Identity = 100/475 (21.05%), Postives = 177/475 (37.26%), Query Frame = 1 
Query:  412 PVLTNILQDHAV-FSYPDISFCFMNPIY---FPP---------MNTSHFAFLMEKYQEYKHYVAVQEEFFKYHIKFGEFLFMKKNQTY------THPAWLAVISCNYLGLPCSHVN-------FIQRYLFPFGACYTFNSTSVEASDAQFRQHMTTNRELEIIIFKAVDIVPGTIS-----------DPFESVLMPSGMLFMIHDKET--WPQVRESYVLDGYSQ-IDLKIINKVHLN-IGNRCRPIKNKFSYYDVFMKTNTSVYGKYS--DCVFQNVQQEVSRYCKC---QWPKMQALSEFHNLPFCLDGHLSLIEFGNCVSKAYTILDGGILDECYMDDCEHTTYETVISQSKFPAMIERKTQQKWLKILADLEKKEIEHFGKSDLYLRSLKSTNKYQVNLSEALNNKDWSLLDEEFVERNFMMIKVMPTSMFIDKVEETEEYPISRLLSDIGGCVGLWIGASLITIFEFLDL 1698
            P+ T     HA    +P ++ C MN +     PP         +N ++             +V  Q+  F+   KF     +  +  Y       H     ++SCN+ G+ C +         + Q +   FG CY FNS             + T+   ++ ++ +   VPG  +           +  E +   +GM   I D+    +P  +   ++ G S  I +  +    ++   NR     N+ S  ++F   N +    YS   C +  +       C C     P+MQ      N+P C   + ++I+   C++KAY   + G  D      C   +++  +S +++PA                 E  +  +F +  +  +   S++KY VN                    N   + V    +    V+ET  Y    LLSDIGG +G+WIG S +T  E ++L
Sbjct:   68 PIKTRTQLKHAQKLDFPVVTICNMNVLRASRLPPKLRTKFDQIINNTNKTSPRNSSNSRNAFVDPQDLSFEETKKFEILHAVTAHDDYRELVSAAHQLEDILLSCNFNGVNCRNSKDPTIPTYWTQTWNDNFGNCYMFNS-------------VKTHNGEKVDLYSSS--VPGESNGLTLQLNLEQNEYLEGITEVAGMKVTISDQGVLPFPGQQGIRIMPGQSTGIQMTKLQTRRIDPFKNRSCESSNEMSDKNLFFGYNMT----YSIMACKYSCLNARKIERCGCTNYNTPEMQK----RNIPLCNRLNSTIID---CLNKAYDTFEDGSCDRECPPSCSEVSFDLTVSSARWPAR--------------SFEVTKYAYFLRVRVLNKIASSSSKYFVN------------------SENIAQVHVYYGELDYLLVQETLAYTFMSLLSDIGGQMGMWIGISALTCAELIEL 484
[Close]
BLAST of acid-sensing ion channel 5 vs. Ensembl Nematostella
Match: EDO34319 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SPS3])

HSP 1 Score: 55.8398 bits (133), Expect = 2.192e-8
Identity = 50/200 (25.00%), Postives = 80/200 (40.00%), Query Frame = 1 
Query:  262 FCRKSTIHGLNHVANSKSVCQRIFWLSICFSASVGLFINM-YYLIEKFIERPVLTNILQDHA-VFSYPDISFCFMNPIY------FPPMNTSHFAFLMEKYQEYKHYVAVQ-EEFFKYHIKFG-------EFLF------------MKKNQTYTHPAWLAVISCNYLGLPCSHVNFIQRYLFPFGACYTFNSTSVEASDA 777
            F  ++T HG+  +  S+S   R+FW+ + F A +G+ ++    L   F++RP  T I   +A    +P ++ C +N I       FP  +     F          ++    E F K H + G       E  F            +KK Q   H     V+ C +  + C+   F   + F +G CYTFN    E   A
Sbjct:   16 FVDRTTCHGIGQINGSQSPLWRVFWV-VTFVAGLGMVVHQGVTLFGTFLDRPTSTTIDMTYAPAMDFPAVTICNLNAIRKDHLSQFPDADVLLKGFSEASTPSVTVFLGKDVESFIKQHSEAGPNVTLDPELAFKDAMVEIFAQSELKKLQMAGHGFEELVLGCTWNNIKCNKGPF---WNFRYGNCYTFNQGMSEKGVA 211
[Close]
BLAST of acid-sensing ion channel 5 vs. Ensembl Medaka
Match: ENSORLT00000031729.1 (acid sensing ion channel subunit 2 [Source:NCBI gene;Acc:101175162])

HSP 1 Score: 73.559 bits (179), Expect = 2.879e-13
Identity = 116/550 (21.09%), Postives = 209/550 (38.00%), Query Frame = 1 
Query:  160 SCVRMSCHSQILNPGMTRNPKKIISYRTLSIGLTFCRKSTIHGLNHV-ANSKSVCQRIFWL-SICFSASVGLFINMYYLIEKFIERPVLTNILQDHAV-FSYPDISFCFMNPIYFPPMNTS------HFAFLMEKYQEYKHYVA--VQEEFFKYHIKFGEF-LFMKKN----------QTYTHPAWLAVISCNYLGLPCSHVNFIQRYLFPFGACYTFNSTSVEASDAQFRQHMTTNRELEIIIFKAVDIVPGTISDPFESVLMPSGMLFMIHDKETWPQVRES--YVLDGYSQIDLKIINKVHL--NIGNRCRPIKNKFSYYDVFMKTNTSVYGKYSDCVFQNVQQEVSRYCKCQWPKMQALSEFHNLPFCLDGHLSLIEFGNCVSKAYTILDGGILDECY-MDDCEHTTYETVISQSKFPAMIERKTQQKWLKILADLEKKEIEHFGKSDLYLRSLKSTNKYQVNLSEALNNKDWSLLDEEFVERNFMMIKVMPTSMFIDKVEETEEYPISRLLSDIGGCVGLWIGASLITIFEFLDLFMDFVETRMI 1728
             C+R +  + I      R  K  ++     +  T   ++ +HGL H+     SV +R FWL ++C S  + L  +   L+  ++  P  T +  + A   ++P ++ C  NPI    +  S      H+  L+   +  +  V   +QE+   +  K  +F LF+                +H     ++SC Y G PC   NF   +   +G CY FN+   E  D +      T   LEI++    D       D  E     +G+   IH +   P V E    V  G+         ++         C     +  ++ V+  T   +     DC  + + +     C C+   M       +  +C     +  ++ +C   A   L     + C     C  T Y   +S  K P+    KT  ++L+          + F KS+ Y                              +  N +++ +   ++  + +E+ + Y ++ LL DIGG +GL+IGAS++TI E  D   + V+ R++
Sbjct:   31 GCIRRASPAMIRKSRQKRRTKPSLA----QVTPTLLSRTRLHGLRHICVPGGSVGRRAFWLLALCTSLGLLLSWSSNRLLH-WLSFPTYTRVHTEWAKELAFPAVTICNNNPIRLYKLTKSDLYFAGHWLGLLLANRTMRPMVLDLLQEDRRAWFQKLSDFRLFLPPRNFEGTNLEFMDRLSHQLDDMLLSCKYRGEPCGAHNFSSVFTR-YGKCYMFNAAE-EGKDLRTTMKGGTGNGLEIMLDIQQDEYLPVWGDT-EDTAFEAGVRVQIHSQAEPPFVHELGFGVAPGFQTFVATQEQRLTYLPPPWGECESRALESGFFQVYSVTACRI-----DCETRYIVEN----CNCRMVHMPG-----DASYC-----TPEQYKDCAEPALAKLSTLESNSCVCRTPCNMTRYNKELSMVKIPS----KTSARYLQ----------KKFNKSEKY------------------------------ITDNILVLDIFFEALNYETIEQKKAYEVAGLLGDIGGQMGLFIGASILTILELFDYAYEVVKDRLL 509
[Close]
BLAST of acid-sensing ion channel 5 vs. Ensembl Medaka
Match: asic4a (acid sensing ion channel subunit family member 4 [Source:NCBI gene;Acc:101159336])

HSP 1 Score: 57.7658 bits (138), Expect = 2.446e-8
Identity = 59/241 (24.48%), Postives = 94/241 (39.00%), Query Frame = 1 
Query: 1009 GNRCRPI-KNKFSYYDVFMKTNTSVYGKYSDCVFQNVQQEVSRYCKCQWPKMQALSEFHNLPFCLDGHLSLIEFGNCVSKAYTILDGGILDECYMD-DCEHTTYETVISQSKFPAMIERKTQQKWLKILADLEKKEIEHFGKSDLYLRSLKSTNKYQVNLSEALNNKDWSLLDEEFVERNFMMIKVMPTSMFIDKVEETEEYPISRLLSDIGGCVGLWIGASLITIFEFLDLFMDFVETRM 1725
            GN CR   K KF  YD +           S C       EV R CKC+   M   ++      C    +S      CV KA   L     D C  +  C  T Y   +S  K P+    K   ++L                          + KY  +              E+++  NF+++ +   ++  + +E+ + Y ++ LL DIGG +GL+IGAS++T+ E LD   + +  R+
Sbjct:  292 GN-CRSTSKEKFPGYDTY---------SISACRLLCETNEVLRVCKCRMVHMPGTADI-----CPPSKIS------CVDKALAQLQKNSGDTCPCETPCNLTRYGKELSMVKIPS----KGSARYL--------------------------SRKYDKS--------------EDYIRDNFLVLDIFFEALNYETIEQKKAYDVAGLLGDIGGQMGLFIGASILTVLEILDYVFEVIRHRL 467
[Close]
BLAST of acid-sensing ion channel 5 vs. Ensembl Medaka
Match: asic1a (acid-sensing ion channel 1 [Source:NCBI gene;Acc:101159102])

HSP 1 Score: 53.1434 bits (126), Expect = 6.012e-7
Identity = 24/86 (27.91%), Postives = 51/86 (59.30%), Query Frame = 1 
Query: 1522 EEFVERNFMMIKVMPTSMFIDKVEETEEYPISRLLSDIGGCVGLWIGASLITIFEFLDLFMDFVETRMIPAKQTKPREHLKNTLLS 1779
            E++++ N +++ +   ++  + +E+ + Y ++ LL DIGG +GL+IGAS++TI E  D   + ++ ++      K     + T+LS
Sbjct:  396 EQYIKDNILVLDIFFEALNYETIEQKKAYEVAGLLGDIGGQMGLFIGASILTILEIFDYLYEVIKYKLCRCSDKKHNNTDQGTVLS 481
[Close]
BLAST of acid-sensing ion channel 5 vs. Ensembl Medaka
Match: ENSORLT00000003455.2 (acid sensing ion channel subunit 2 [Source:NCBI gene;Acc:101175162])

HSP 1 Score: 53.1434 bits (126), Expect = 7.248e-7
Identity = 22/69 (31.88%), Postives = 45/69 (65.22%), Query Frame = 1 
Query: 1522 EEFVERNFMMIKVMPTSMFIDKVEETEEYPISRLLSDIGGCVGLWIGASLITIFEFLDLFMDFVETRMI 1728
            E+++  N +++ +   ++  + +E+ + Y ++ LL DIGG +GL+IGAS++TI E  D   + V+ R++
Sbjct:  386 EKYITDNILVLDIFFEALNYETIEQKKAYEVAGLLGDIGGQMGLFIGASILTILELFDYAYEVVKDRLL 454

HSP 2 Score: 51.6026 bits (122), Expect = 2.084e-6
Identity = 63/254 (24.80%), Postives = 104/254 (40.94%), Query Frame = 1 
Query:  247 SIGLTFCRKSTIHGLNHV-ANSKSVCQRIFWL-SICFSASVGLFINMYYLIEKFIERPVLTNILQDHAV-FSYPDISFCFMNPIYFPPMNTS------HFAFLMEKYQEYKHYVA--VQEEFFKYHIKFGEF-LFMKKN----------QTYTHPAWLAVISCNYLGLPCSHVNFIQRYLFPFGACYTFNSTSVEASDAQFRQHMTTNRELEIIIFKAVDIVPGTISDPFESVLMPSGMLFMIHDKETWPQVRE 942
            S+  T   ++ +HGL H+     SV +R FWL ++C S  + L  +   L+  ++  P  T +  + A   ++P ++ C  NPI    +  S      H+  L+   +  +  V   +QE+   +  K  +F LF+                +H     ++SC Y G PC   NF   +   +G CY FN+   E  D +      T   LEI++    D       D  E     +G+   IH +   P V E
Sbjct:    5 SVTPTLLSRTRLHGLRHICVPGGSVGRRAFWLLALCTSLGLLLSWSSNRLLH-WLSFPTYTRVHTEWAKELAFPAVTICNNNPIRLYKLTKSDLYFAGHWLGLLLANRTMRPMVLDLLQEDRRAWFQKLSDFRLFLPPRNFEGTNLEFMDRLSHQLDDMLLSCKYRGEPCGAHNFSSVFT-RYGKCYMFNAAE-EGKDLRTTMKGGTGNGLEIMLDIQQDEYLPVWGDT-EDTAFEAGVRVQIHSQAEPPFVHE 254
[Close]
BLAST of acid-sensing ion channel 5 vs. Ensembl Medaka
Match: ENSORLT00000021925.2 (acid-sensing ion channel 1C [Source:NCBI gene;Acc:101174951])

HSP 1 Score: 51.9878 bits (123), Expect = 1.414e-6
Identity = 22/69 (31.88%), Postives = 45/69 (65.22%), Query Frame = 1 
Query: 1522 EEFVERNFMMIKVMPTSMFIDKVEETEEYPISRLLSDIGGCVGLWIGASLITIFEFLDLFMDFVETRMI 1728
            E+++  N +++ +   ++  +K+E+ + Y I+ LL DIGG +GL+IGAS++TI E  D   +  + +++
Sbjct:  395 EQYIGDNILVLDIFFEALNYEKIEQKKAYEIAGLLGDIGGQMGLFIGASVLTILEIFDYLYEVFKDKVL 463
[Close]
BLAST of acid-sensing ion channel 5 vs. Planmine SMEST
Match: SMESG000028094.1 (SMESG000028094.1)

HSP 1 Score: 1224.15 bits (3166), Expect = 0.000e+0
Identity = 587/587 (100.00%), Postives = 587/587 (100.00%), Query Frame = 1 
Query:  172 MSCHSQILNPGMTRNPKKIISYRTLSIGLTFCRKSTIHGLNHVANSKSVCQRIFWLSICFSASVGLFINMYYLIEKFIERPVLTNILQDHAVFSYPDISFCFMNPIYFPPMNTSHFAFLMEKYQEYKHYVAVQEEFFKYHIKFGEFLFMKKNQTYTHPAWLAVISCNYLGLPCSHVNFIQRYLFPFGACYTFNSTSVEASDAQFRQHMTTNRELEIIIFKAVDIVPGTISDPFESVLMPSGMLFMIHDKETWPQVRESYVLDGYSQIDLKIINKVHLNIGNRCRPIKNKFSYYDVFMKTNTSVYGKYSDCVFQNVQQEVSRYCKCQWPKMQALSEFHNLPFCLDGHLSLIEFGNCVSKAYTILDGGILDECYMDDCEHTTYETVISQSKFPAMIERKTQQKWLKILADLEKKEIEHFGKSDLYLRSLKSTNKYQVNLSEALNNKDWSLLDEEFVERNFMMIKVMPTSMFIDKVEETEEYPISRLLSDIGGCVGLWIGASLITIFEFLDLFMDFVETRMIPAKQTKPREHLKNTLLSKKYLILNCNKLSKLDSIYENSATLNLANLKCTKVTLKESFSEKDIFKISNV 1932
            MSCHSQILNPGMTRNPKKIISYRTLSIGLTFCRKSTIHGLNHVANSKSVCQRIFWLSICFSASVGLFINMYYLIEKFIERPVLTNILQDHAVFSYPDISFCFMNPIYFPPMNTSHFAFLMEKYQEYKHYVAVQEEFFKYHIKFGEFLFMKKNQTYTHPAWLAVISCNYLGLPCSHVNFIQRYLFPFGACYTFNSTSVEASDAQFRQHMTTNRELEIIIFKAVDIVPGTISDPFESVLMPSGMLFMIHDKETWPQVRESYVLDGYSQIDLKIINKVHLNIGNRCRPIKNKFSYYDVFMKTNTSVYGKYSDCVFQNVQQEVSRYCKCQWPKMQALSEFHNLPFCLDGHLSLIEFGNCVSKAYTILDGGILDECYMDDCEHTTYETVISQSKFPAMIERKTQQKWLKILADLEKKEIEHFGKSDLYLRSLKSTNKYQVNLSEALNNKDWSLLDEEFVERNFMMIKVMPTSMFIDKVEETEEYPISRLLSDIGGCVGLWIGASLITIFEFLDLFMDFVETRMIPAKQTKPREHLKNTLLSKKYLILNCNKLSKLDSIYENSATLNLANLKCTKVTLKESFSEKDIFKISNV
Sbjct:    1 MSCHSQILNPGMTRNPKKIISYRTLSIGLTFCRKSTIHGLNHVANSKSVCQRIFWLSICFSASVGLFINMYYLIEKFIERPVLTNILQDHAVFSYPDISFCFMNPIYFPPMNTSHFAFLMEKYQEYKHYVAVQEEFFKYHIKFGEFLFMKKNQTYTHPAWLAVISCNYLGLPCSHVNFIQRYLFPFGACYTFNSTSVEASDAQFRQHMTTNRELEIIIFKAVDIVPGTISDPFESVLMPSGMLFMIHDKETWPQVRESYVLDGYSQIDLKIINKVHLNIGNRCRPIKNKFSYYDVFMKTNTSVYGKYSDCVFQNVQQEVSRYCKCQWPKMQALSEFHNLPFCLDGHLSLIEFGNCVSKAYTILDGGILDECYMDDCEHTTYETVISQSKFPAMIERKTQQKWLKILADLEKKEIEHFGKSDLYLRSLKSTNKYQVNLSEALNNKDWSLLDEEFVERNFMMIKVMPTSMFIDKVEETEEYPISRLLSDIGGCVGLWIGASLITIFEFLDLFMDFVETRMIPAKQTKPREHLKNTLLSKKYLILNCNKLSKLDSIYENSATLNLANLKCTKVTLKESFSEKDIFKISNV 587
[Close]
BLAST of acid-sensing ion channel 5 vs. Planmine SMEST
Match: SMESG000072895.1 (SMESG000072895.1)

HSP 1 Score: 593.964 bits (1530), Expect = 0.000e+0
Identity = 278/504 (55.16%), Postives = 366/504 (72.62%), Query Frame = 1 
Query:  232 SYRT---LSIGLTFCRKSTIHGLNHVANSKSVCQRIFWLSICFSASVGLFINMYYLIEKFIERPVLTNILQDHAVFSYPDISFCFMNPIYFPPMNTSHFAFLMEKYQEYKHYVAVQEEFFKYHIKFGEFLFMKKNQTYTHPAWLAVISCNYLGLPCSHVNFIQRYLFPFGACYTFNSTSVEASDAQFRQHMTTNRELEIIIFKAVDIVPGTISDPFESVLMPSGMLFMIHDKETWPQVRESYVLDGYSQIDLKIINKVHLNIGNRCRPIKNKFSYYDVFMKTNTSVYGKYSDCVFQNVQQEVSRYCKCQWPKMQALSEFHNLPFCLDGHLSLIEFGNCVSKAYTILDGGILDECYMDDCEHTTYETVISQSKFPAMIERKTQQKWLKILADLEKKEIEHFGKSDLYLRSLK-----STNKYQVNLSEALNNKDWSLLDEEFVERNFMMIKVMPTSMFIDKVEETEEYPISRLLSDIGGCVGLWIGASLITIFEFLDLFMDFVET 1719
            S+RT   ++I L FC++STIHGLN +A  KSV QR FW+ IC SAS+G+ IN YYLI+KF+ERPVLTN+LQDH  F YPD+SFCF NPIYFPP  + + +F+M +Y++Y  +      F    IKF +FL+M +N TYTHP W  ++ C Y  L CS  + I R+LF +GACYTFN +  E+S     ++   N+EL+ II+KAVDI      DPF++++MPSG+L MIHD+ TWP+++ESY+LD YSQ++LKIINK HLNIG  CR +KNKF YYDVF+K N SVYGKYSDCV+QNVQ+ V+++C+CQW +MQ LS ++NLPFC+D  +      +C+  AY  L+ G LD CY+DDCEHTTYETVISQS FPA+++RKT  +W+K L ++E +E E +G SDL   +LK     + N    N+S A  +  + L+D EFVERNFMM+K++PTS F+D +EETE YP SRLL DIGG VGLW+GASLIT+FE  DL  D +ET
Sbjct:   20 SWRTQKYINITLNFCQRSTIHGLNQLAFPKSVQQRYFWIFICLSASIGMVINNYYLIDKFLERPVLTNVLQDHTAFVYPDVSFCFTNPIYFPPAKSPYRSFIMAQYKKYIQFKKYPSNFLTVKIKFADFLYMTRNNTYTHPLWSVLVECRYQDLQCSFHDLILRHLFAYGACYTFNYSRFESSAGN--KYRYGNKELDFIIYKAVDIPIANFGDPFDNIMMPSGILLMIHDRNTWPKLQESYILDEYSQVNLKIINKQHLNIGKTCRTVKNKFIYYDVFIKQNISVYGKYSDCVYQNVQEAVAKHCQCQWQEMQVLSHYYNLPFCIDHVVPPRLNFSCLDTAYGDLNNGSLDYCYLDDCEHTTYETVISQSHFPALVDRKTNIQWMKHLVEIETRETEFYGFSDLKFNALKWDKIQNANLTIANISVAFKSGRYDLMDLEFVERNFMMVKIVPTSFFMDMIEETEGYPFSRLLGDIGGSVGLWLGASLITVFEVFDLLSDLIET 521
[Close]
BLAST of acid-sensing ion channel 5 vs. Planmine SMEST
Match: SMESG000024270.1 (SMESG000024270.1)

HSP 1 Score: 497.278 bits (1279), Expect = 1.890e-169
Identity = 236/521 (45.30%), Postives = 344/521 (66.03%), Query Frame = 1 
Query:  208 TRNPKKIISYRTLSIGLTFCRKSTIHGLNHVANSKSVCQRIFWLSICFSASVGLFINMYYLIEKFIERPVLTNILQDHAVFSYPDISFCFMNPIYFPPMNTSHFAFLMEKYQEYKHYVAVQEEFFKYHIKFGEFLFMKKNQTYTHPAWLAVISCNYLGLPCSHVNFIQRYLFPFGACYTFNSTSVEASDAQ----FRQHMTTNRELEIIIFKAVDIVPGTISDPFESVLMPSGMLFMIHDKETWPQVRESYVLDGYSQIDLKIINKVHLNIGNRCRPIKNKFSYYDVFMKTNTSVYGKYSDCVFQNVQQEVSRYCKCQWPKMQALSEFHNLPFCLDGHLSLIEFGNCVSKAYTILDGGILDECYMDDCEHTTYETVISQSKFPAMIERKTQQKWLKILADLEKKEIEHFGKSDLYLRSLKSTN-KYQVNLSEALNNKDWSLLDEEFVERNFMMIKVMPTSMFIDKVEETEEYPISRLLSDIGGCVGLWIGASLITIFEFLDLFMDFVETRMIPAKQTKPRE 1755
            + N K +I  R L+I L FC +ST HGL+ +A ++ + QR+FW++IC  AS+G  IN+YYL++K++E P+LTN++Q++  F +PDIS CF NPIY+PP ++     LM+ YQ Y +Y    + FF   +   E+LFM K   Y H AW +++SC+Y+G  CS+ +F  R+++PFG C+TFNST +   D +    F    +     +I ++KAVD+      DPF+ V +P G+L MIHD+ T+P +  SY+LD YSQIDL+I +K HLN+ NRC+  +  ++Y D+F   +T+   K  DCV+  +Q  V + C+C W     +    +  +CLDG  S+    +C+ K +  +    L +CY D C+H  +E+VISQSKFPA+ ER T   WLKILADLE+ E+++FG+S+L  ++LK  N   ++ L++A   +   LLDEEFV+RNFMM++V+P S F+DKVEET EYPISRLLSD+GGCVGLW+GASLITIFEFLDL  DF +   +  K+ + RE
Sbjct:    4 SSNHKSVIWGRFLNIVLHFCHRSTFHGLSQIARARKIRQRVFWITICGGASLGFLINIYYLLDKYLETPILTNVIQNYQRFIFPDISICFTNPIYYPPKDSEAHKLLMDNYQNYLYYKKNMDPFFSNRVNLAEYLFMTKTDFYGHHAWGSIVSCSYMGHDCSYKHFETRHIYPFGVCHTFNSTKIMMKDIRKINSFSGMQSVKPFFQITVYKAVDMGENFNVDPFDDVTIPGGILVMIHDEHTFPFIGNSYILDAYSQIDLRITSKQHLNVNNRCKISQEFYTYMDLFENKSTAFSAKTEDCVYITIQINVMKNCQCIWQHFPTILVPPSTRYCLDGTFSVNHLKDCLRKTHAEITEEYLPKCYQDLCDHKVFESVISQSKFPAVTERGTHASWLKILADLERNEMKYFGQSELRTKALKMINASTRMTLNKAHKMQRIDLLDEEFVDRNFMMLRVVPNSFFMDKVEETMEYPISRLLSDVGGCVGLWVGASLITIFEFLDLIFDFFDV-TVQLKKLRMRE 523
[Close]
BLAST of acid-sensing ion channel 5 vs. Planmine SMEST
Match: SMESG000047581.1 (SMESG000047581.1)

HSP 1 Score: 428.328 bits (1100), Expect = 2.125e-141
Identity = 231/570 (40.53%), Postives = 342/570 (60.00%), Query Frame = 1 
Query:  238 RTLSIGLTFCRKSTIHGLNHVANSKSVCQRIFWLSICFSASVGLFINMYYLIEKFIERPVLTNILQDHAVFSYPDISFCFMNPIYFPPMNTSHFAFLMEKYQEYKHYVAVQEEFFK---------YHIKFGEFLFMKKNQTYTHPAWLAVISCNYLGLPCSHVNFIQRYLFPFGACYTFNSTSVEASDAQFRQHMTT----NRELEIIIFKAVDIVPGTISDPFESVLMPSGMLFMIHDKETWPQVRESYVLDGYSQIDLKIINKVHLNIGNRCRPIKNKFSYYDVFMKTNTS--VYGKYSDCVFQNVQQEVSRYCKCQWPKMQALSEFHNLPFCLDGHLSLIEFGNCVSKAYTILDGGILDE-CYMDDCEHTTYETVISQSKFPAMIERKTQQKWLKILADLEKKEIEHFGKSDLY-LRSLKSTNKYQVN---LSEALNNKDWSLLDEEFVERNFMMIKVMPTSMFIDKVEETEEYPISRLLSDIGGCVGLWIGASLITIFEFLDLFMDFVETRMIPAKQTKPREHLKNTLLSKKYLILNCNKLSKLDSIYENS----ATLNLANLKCT 1875
            R  ++ L F R+STIHGLNH+A ++S   R+FWL+I  SAS+G  +N++YLIEKF++ PVLTN+  D   F+YPD+S C +NPIYFPP NT +   L+   +EY  Y      F             I+  ++LFM     Y+HP+W A+I C YL   C++ +F  R+++P+G C+TFN T +     +  +  T       + +++I+KA++       DPF  +  PSG+L MIH+  T+P + ES+V+D ++Q+DLKI  K HL+   +C  I+N ++YYD   KTNTS    G+  DC+F  +Q  ++ YC CQ  KM  L +   LPFC D          C+  +   +D   L + CY D CEH ++ TV+S SK+PA+ ER+T   WL+ L DLE  EIEH+G+S+L  +  LKS +  + N   + E  +     LL+E+F+ +NFM ++ +P+S+F+D VEETEEYP+SRLLSDIGGCVGLW+GASLIT+FEF+DL +D  E   I   +++     K    ++K  ILN +K    ++   N+    +TLN  +  CT
Sbjct:   52 RLGTVLLHFSRRSTIHGLNHLAQARSAKHRLFWLTISCSASLGFCVNLFYLIEKFLQTPVLTNVFHDFNNFTYPDLSICIVNPIYFPPENTRYRNELISTIEEY--YRLTNSSFHDSKSSYNANLQKIELSDYLFMHSKLEYSHPSWSAIILCRYLKKKCNYTHFETRHIWPYGNCFTFNGTKMGLEGTRDVKKNTVLNGWRPDFKLVIYKALEYPVNLQIDPFNDINKPSGVLVMIHEPNTYPHIGESFVVDSFTQVDLKITTKSHLSSLKKCESIRNNYTYYD--FKTNTSNIFVGRQGDCLFSIIQTNIANYCGCQLHKMPILEKHKQLPFCYDKRFRNENLTYCLHASLDDVDREQLRQLCYKDLCEHPSFSTVVSHSKYPAVRERQTHMLWLEHLKDLELLEIEHYGQSELINMAILKSNSSLKHNYKSIREIYDKGRIDLLNEKFINKNFMHLRFVPSSLFMDHVEETEEYPLSRLLSDIGGCVGLWVGASLITVFEFIDLLLDLSE---IIRYRSQATVVYKQMCRNQKSFILNNSKSLVPNTYLSNNNIPDSTLNEPSYSCT 614
[Close]
BLAST of acid-sensing ion channel 5 vs. Planmine SMEST
Match: SMESG000009914.1 (SMESG000009914.1)

HSP 1 Score: 425.246 bits (1092), Expect = 2.326e-140
Identity = 214/537 (39.85%), Postives = 332/537 (61.82%), Query Frame = 1 
Query:  211 RNPKKIISYRTLSIGLTFCRKSTIHGLNHVANSKSVCQRIFWLSICFSASVGLFINMYYLIEKFIERPVLTNILQDHAVFSYPDISFCFMNPIYFPPMNTSHFAFLMEKYQEY---------KHYVAVQEEFFKYHIKFGEFLFMKKNQTYTHPAWLAVISCNYLGLPCSHVNFIQRYLFPFGACYTFNSTSVEAS---DAQFRQHMTTNR-ELEIIIFKAVDIVPGTISDPFESVLMPSGMLFMIHDKETWPQVRESYVLDGYSQIDLKIINKVHLNIGNRCRPIKNKFSYYDVFMKTNTSVYGKYSDCVFQNVQQEVSRYCKCQWPKMQALSEFHNLPFC----LDGHLSLIEFGNCVSKAYTILDG-GILDECYMDDCEHTTYETVISQSKFPAMIERKTQQKWLKILADLEKKEIEHFGKSDLYLRSLKSTN----------KYQVNLSEALNNKDW-------SLLDEEFVERNFMMIKVMPTSMFIDKVEETEEYPISRLLSDIGGCVGLWIGASLITIFEFLDLFMDFVE 1716
            ++P  II  R  +I L F R+STIHGLNH+A ++S  +R+FWL I   A+VG F+N++YL+EKFI+ P+LTN   D+  F YPDI+FC +NPI FPP  ++ + +L+     Y         K+  + + E F   ++  ++LF+K+N +Y+H  W A++ C YL  PCS  +F   +++P+G C+TFN+T ++ +   D Q    +   R +  III+K+++ +   + DPF  +  PSG+L MIH+ ET+P V +S+++D Y+Q+DLKI  K HL    +C P +  ++Y D   K   +  G+  DCVF+ +Q ++++ CKCQ   M  L +    PFC    L   L++     C+++    +D   I   CY D C H +Y TVIS SK+PA+ +R+T   WLK L  +EK+EIE++G S+L+ +++K  +          + Q+ + +  ++ D         L+DE F+++NFM ++ +P+S+F+D +EETEEYPISRLLSDIGGCVGLW+GASLITIFEF DL MD  +
Sbjct:   22 KSPTIIIFKRLGTIFLHFTRRSTIHGLNHLAQARSAKRRLFWLFISTCATVGFFVNLFYLVEKFIQTPILTNTFHDYTSFIYPDITFCLVNPINFPPKTSAQYKYLIGIINNYIRNEESLFHKYINSSKNEDFLPKLELMDYLFIKENISYSHSPWSAIVDCRYLHYPCSWEHFDVHFVWPYGNCFTFNATKMQKNLTRDVQRNMQLNGFRPDFRIIIYKSINRLSSVVHDPFNDITKPSGVLVMIHEIETYPHVSDSFIVDSYTQVDLKITTKSHLESLKKCNPNRQNYTYCDYRSKKCQTFQGRNIDCVFEIIQNKIAKNCKCQMHTMPVLMKNRFYPFCYSLMLSNPLNVSSIRKCLNQTIVGVDKQSIHSICYQDLCSHPSYSTVISHSKYPAIQDRQTHSLWLKKLIVIEKREIENYGISNLFQKAIKRNHSTLLRNPNFMENQIPIGKRFDSIDAVYRDMRDDLIDELFIDQNFMQLRFVPSSLFMDHIEETEEYPISRLLSDIGGCVGLWVGASLITIFEFFDLLMDLSD 558
The following BLAST results are available for this feature:
BLAST of acid-sensing ion channel 5 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ASIC56.901e-1521.60acid sensing ion channel subunit family member 5 [... [more]
SCNN1B2.020e-820.00sodium channel epithelial 1 beta subunit [Source:H... [more]
SCNN1B2.446e-820.00sodium channel epithelial 1 beta subunit [Source:H... [more]
SCNN1B3.604e-821.01sodium channel epithelial 1 beta subunit [Source:H... [more]
AC093830.15.417e-821.38acid sensing ion channel subunit family member 5 [... [more]
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BLAST of acid-sensing ion channel 5 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
asic-21.715e-1029.41Degenerin-like protein asic-2 [Source:UniProtKB/S... [more]
del-41.252e-821.89DEgenerin Like [Source:UniProtKB/TrEMBL;Acc:P9183... [more]
delm-14.039e-626.59DEgenerin Linked to Mechanosensation [Source:UniP... [more]
unc-85.711e-637.70Degenerin unc-8 [Source:UniProtKB/Swiss-Prot;Acc:... [more]
unc-86.439e-637.70Degenerin unc-8 [Source:UniProtKB/Swiss-Prot;Acc:... [more]
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BLAST of acid-sensing ion channel 5 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of acid-sensing ion channel 5 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
asic1c2.091e-1521.65acid-sensing (proton-gated) ion channel 1c [Source... [more]
asic1c2.128e-830.38acid-sensing (proton-gated) ion channel 1c [Source... [more]
asic4b2.481e-833.73acid-sensing (proton-gated) ion channel family mem... [more]
asic4a2.846e-823.58acid-sensing (proton-gated) ion channel family mem... [more]
asic4a4.840e-823.58acid-sensing (proton-gated) ion channel family mem... [more]
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BLAST of acid-sensing ion channel 5 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ASIC59.460e-1322.87acid sensing ion channel subunit family member 5 [... [more]
ASIC44.294e-730.43acid sensing ion channel subunit family member 4 [... [more]
ASIC41.172e-633.33acid sensing ion channel subunit family member 4 [... [more]
ASIC43.194e-637.29acid sensing ion channel subunit family member 4 [... [more]
ASIC14.023e-631.08acid sensing ion channel subunit 1 [Source:NCBI ge... [more]
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BLAST of acid-sensing ion channel 5 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Asic57.256e-1921.83acid-sensing (proton-gated) ion channel family mem... [more]
Asic53.140e-1821.96acid-sensing (proton-gated) ion channel family mem... [more]
Scnn1b5.218e-822.63sodium channel, nonvoltage-gated 1 beta [Source:MG... [more]
Asic32.171e-736.23acid-sensing (proton-gated) ion channel 3 [Source:... [more]
Asic21.250e-628.99acid-sensing (proton-gated) ion channel 2 [Source:... [more]
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BLAST of acid-sensing ion channel 5 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q9R0Y1|ASIC5_MOUSE5.075e-1821.83Acid-sensing ion channel 5 OS=Mus musculus OX=1009... [more]
sp|Q9R0W5|ASIC5_RAT1.091e-1722.09Acid-sensing ion channel 5 OS=Rattus norvegicus OX... [more]
sp|Q708S6|ASI1C_DANRE1.578e-1421.65Acid-sensing ion channel 1C OS=Danio rerio OX=7955... [more]
sp|Q9NY37|ASIC5_HUMAN3.314e-1421.60Acid-sensing ion channel 5 OS=Homo sapiens OX=9606... [more]
sp|Q22851|ASIC2_CAEEL2.182e-929.41Degenerin-like protein asic-2 OS=Caenorhabditis el... [more]
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BLAST of acid-sensing ion channel 5 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A0R3SIE12.697e-13241.13Uncharacterized protein OS=Hymenolepis diminuta OX... [more]
A0A564Z6I12.756e-13241.13Uncharacterized protein OS=Hymenolepis diminuta OX... [more]
A0A183SCX19.733e-13241.39Uncharacterized protein OS=Schistocephalus solidus... [more]
A0A3P7LUS43.760e-12940.11Uncharacterized protein OS=Dibothriocephalus latus... [more]
A0A0R3TJX91.858e-12340.88Uncharacterized protein OS=Rodentolepis nana OX=10... [more]
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BLAST of acid-sensing ion channel 5 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
asic4a3.358e-831.40acid-sensing ion channel 4 [Source:NCBI gene;Acc:1... [more]
asic4b3.389e-835.29acid-sensing ion channel 4 [Source:NCBI gene;Acc:1... [more]
asic1c2.101e-727.91acid-sensing ion channel 1C-like [Source:NCBI gene... [more]
asic1c2.218e-727.91acid-sensing ion channel 1C-like [Source:NCBI gene... [more]
asic1c4.711e-727.91acid-sensing ion channel 1C-like [Source:NCBI gene... [more]
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BLAST of acid-sensing ion channel 5 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 3
Match NameE-valueIdentityDescription
ASIC58.425e-721.35acid sensing ion channel subunit family member 5 [... [more]
asic1a4.819e-624.71acid-sensing (proton-gated) ion channel 1a [Source... [more]
ASIC55.079e-634.52acid sensing ion channel subunit family member 5 [... [more]
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BLAST of acid-sensing ion channel 5 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of acid-sensing ion channel 5 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO494524.450e-1722.94Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO394131.133e-1321.65Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO394462.372e-1022.27Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO421371.380e-921.05Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO343192.192e-825.00Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of acid-sensing ion channel 5 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSORLT00000031729.12.879e-1321.09acid sensing ion channel subunit 2 [Source:NCBI ge... [more]
asic4a2.446e-824.48acid sensing ion channel subunit family member 4 [... [more]
asic1a6.012e-727.91acid-sensing ion channel 1 [Source:NCBI gene;Acc:1... [more]
ENSORLT00000003455.27.248e-731.88acid sensing ion channel subunit 2 [Source:NCBI ge... [more]
ENSORLT00000021925.21.414e-631.88acid-sensing ion channel 1C [Source:NCBI gene;Acc:... [more]
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BLAST of acid-sensing ion channel 5 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000028094.10.000e+0100.00SMESG000028094.1[more]
SMESG000072895.10.000e+055.16SMESG000072895.1[more]
SMESG000024270.11.890e-16945.30SMESG000024270.1[more]
SMESG000047581.12.125e-14140.53SMESG000047581.1[more]
SMESG000009914.12.326e-14039.85SMESG000009914.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30009148 ID=SMED30009148|Name=acid-sensing ion channel 5|organism=Schmidtea mediterranea sexual|type=transcript|length=1998bp
ATTTTATAAAAAACATTCACCAGACGGAAAATTCATGTTTGAAAATTACA
ATATTTAAAGTGCCCAAGAGACTGAAAAGGAAAAATATATCTTATATAAT
TACTCCTTGAAATAACATCTCGATTTCTTAGATCTCGGCAAAATTATTAC
GCTTTGTATTCATGTGTCAGAATGAGTTGTCATTCACAGATCCTCAATCC
AGGAATGACTCGAAATCCGAAAAAGATTATCTCTTATCGAACGTTGAGTA
TCGGGTTGACATTTTGTAGGAAAAGCACAATTCATGGCTTGAATCACGTT
GCAAACTCCAAGAGTGTTTGCCAAAGGATATTTTGGCTCTCTATTTGTTT
TAGTGCATCAGTCGGGTTGTTTATAAATATGTATTATTTGATTGAAAAAT
TTATCGAAAGACCTGTTCTTACGAACATTCTACAAGATCATGCGGTGTTT
AGTTATCCAGATATCTCTTTTTGTTTCATGAATCCCATTTATTTTCCACC
AATGAATACCTCTCACTTCGCTTTCCTAATGGAAAAATATCAGGAATATA
AACATTATGTAGCGGTTCAAGAAGAATTCTTCAAGTATCATATAAAATTT
GGAGAATTTCTTTTCATGAAAAAAAACCAAACGTACACCCATCCAGCTTG
GTTGGCAGTTATTAGCTGTAACTACCTCGGTTTGCCTTGCTCTCACGTCA
ATTTTATCCAAAGATATCTCTTTCCTTTTGGAGCTTGTTATACATTCAAT
TCGACATCTGTCGAAGCGTCAGATGCTCAATTTCGTCAACATATGACAAC
TAATAGAGAATTGGAGATTATTATATTCAAAGCCGTGGACATTGTGCCTG
GAACCATTAGTGACCCATTTGAAAGTGTTCTAATGCCTTCCGGAATGCTC
TTTATGATTCACGACAAAGAAACCTGGCCACAAGTCAGAGAAAGTTATGT
TCTTGATGGTTATAGTCAGATTGATTTGAAAATCATCAACAAAGTTCACC
TTAACATAGGTAATAGATGCCGACCAATAAAGAATAAATTTTCGTATTAT
GATGTCTTCATGAAAACCAACACCTCAGTTTATGGGAAATATTCAGATTG
TGTTTTTCAGAATGTTCAACAAGAAGTATCACGATATTGCAAATGCCAGT
GGCCAAAAATGCAAGCACTTTCCGAATTTCACAATCTTCCTTTTTGTCTC
GATGGTCATTTGAGTCTCATTGAATTTGGTAATTGCGTATCTAAGGCTTA
TACGATTTTAGATGGCGGAATTCTTGACGAATGTTACATGGATGATTGTG
AACACACAACCTATGAGACCGTAATTTCCCAAAGTAAATTTCCAGCAATG
ATCGAACGAAAAACTCAACAAAAATGGTTGAAAATTCTCGCGGATTTAGA
GAAGAAAGAAATTGAGCATTTTGGAAAATCAGATCTTTATTTGAGGTCTT
TGAAATCAACAAATAAATATCAAGTTAATCTCAGTGAAGCTCTCAATAAT
AAAGATTGGTCTTTGTTGGACGAAGAATTTGTTGAAAGAAATTTTATGAT
GATAAAGGTGATGCCAACTTCTATGTTTATTGACAAAGTAGAAGAAACTG
AAGAATATCCAATTAGCCGGTTGCTCAGTGACATTGGAGGTTGCGTCGGT
CTCTGGATCGGAGCAAGTCTCATTACAATATTTGAATTTTTAGATTTATT
CATGGACTTTGTGGAAACTCGAATGATTCCTGCAAAACAAACCAAACCCA
GAGAACATTTAAAAAATACTTTGCTGTCGAAAAAATATTTGATTCTCAAT
TGTAATAAGTTGTCAAAACTTGATTCGATTTACGAAAACTCAGCAACCTT
GAACTTAGCCAATCTGAAATGTACAAAGGTCACTTTGAAAGAGTCGTTTT
CTGAAAAAGACATCTTTAAAATATCCAATGTTTAAAAGTTAGAAAAATGC
CAATATGTTTCAGTTGTTTATTTACATTTTCTGAGGAAAGATTGTTGT
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protein sequence of SMED30009148-orf-1

>SMED30009148-orf-1 ID=SMED30009148-orf-1|Name=SMED30009148-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=588bp
MSCHSQILNPGMTRNPKKIISYRTLSIGLTFCRKSTIHGLNHVANSKSVC
QRIFWLSICFSASVGLFINMYYLIEKFIERPVLTNILQDHAVFSYPDISF
CFMNPIYFPPMNTSHFAFLMEKYQEYKHYVAVQEEFFKYHIKFGEFLFMK
KNQTYTHPAWLAVISCNYLGLPCSHVNFIQRYLFPFGACYTFNSTSVEAS
DAQFRQHMTTNRELEIIIFKAVDIVPGTISDPFESVLMPSGMLFMIHDKE
TWPQVRESYVLDGYSQIDLKIINKVHLNIGNRCRPIKNKFSYYDVFMKTN
TSVYGKYSDCVFQNVQQEVSRYCKCQWPKMQALSEFHNLPFCLDGHLSLI
EFGNCVSKAYTILDGGILDECYMDDCEHTTYETVISQSKFPAMIERKTQQ
KWLKILADLEKKEIEHFGKSDLYLRSLKSTNKYQVNLSEALNNKDWSLLD
EEFVERNFMMIKVMPTSMFIDKVEETEEYPISRLLSDIGGCVGLWIGASL
ITIFEFLDLFMDFVETRMIPAKQTKPREHLKNTLLSKKYLILNCNKLSKL
DSIYENSATLNLANLKCTKVTLKESFSEKDIFKISNV*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000099neuron
PLANA:0000418head
Vocabulary: INTERPRO
TermDefinition
IPR001873ENaC
Vocabulary: biological process
TermDefinition
GO:0006814sodium ion transport
GO:0006810transport
GO:0006811ion transport
GO:0015992proton transport
GO:0034220ion transmembrane transport
GO:0035725sodium ion transmembrane transport
Vocabulary: cellular component
TermDefinition
GO:0016020membrane
GO:0005886plasma membrane
GO:0016021integral component of membrane
Vocabulary: molecular function
TermDefinition
GO:0005272sodium channel activity
GO:0015252hydrogen ion channel activity
GO:0015280ligand-gated sodium channel activity
GO:0044736acid-sensing ion channel activity
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR001873Epithelial sodium channelPRINTSPR01078AMINACHANNELcoord: 91..107
score: 25.88
coord: 177..193
score: 41.41
coord: 475..489
score: 40.27
coord: 489..505
score: 46.59
coord: 163..174
score: 31.33
IPR001873Epithelial sodium channelPFAMPF00858ASCcoord: 31..509
e-value: 4.1E-55
score: 187.5
IPR001873Epithelial sodium channelPANTHERPTHR11690AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATEDcoord: 32..526
NoneNo IPR availablePANTHERPTHR11690:SF222PICKPOCKET 6-RELATEDcoord: 32..526
NoneNo IPR availableTMHMMTMhelixcoord: 52..74