Cyclin-dependent kinase 9
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30009003 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 1
Homology
BLAST of Cyclin-dependent kinase 9 vs. Ensembl Human
Match: CDK9 (cyclin dependent kinase 9 [Source:HGNC Symbol;Acc:HGNC:1780]) HSP 1 Score: 266.159 bits (679), Expect = 4.027e-85 Identity = 125/216 (57.87%), Postives = 160/216 (74.07%), Query Frame = 1
Query: 115 HVDQYEKLQKIGQGTFGEVFKVRDIQTKKYYALKRIKLEQEKEGFPITALREIKILQSLNHPNIVCLREICCSSPTKEKLYKPEFYLLFDLCDHDLAGLLSDQNMKFSLPQRKSIMKQLFTGIFYLHRNNVIHRDLKAANILIEKHGTLKIADFGLARYTIKSPKPDHPPKYTSRVVTMWYRPPEILLNDRHYDKSVDMWGAGCIMAELWTKYPIM 762
V +YEKL KIGQGTFGEVFK R +T + ALK++ +E EKEGFPITALREIKILQ L H N+V L EIC + + K YL+FD C+HDLAGLLS+ +KF+L + K +M+ L G++Y+HRN ++HRD+KAAN+LI + G LK+ADFGLAR K P +YT+RVVT+WYRPPE+LL +R Y +D+WGAGCIMAE+WT+ PIM
Sbjct: 15 EVSKYEKLAKIGQGTFGEVFKARHRKTGQKVALKKVLMENEKEGFPITALREIKILQLLKHENVVNLIEICRTKASPYNRCKGSIYLVFDFCEHDLAGLLSNVLVKFTLSEIKRVMQMLLNGLYYIHRNKILHRDMKAANVLITRDGVLKLADFGLAR-AFSLAKNSQPNRYTNRVVTLWYRPPELLLGERDYGPPIDLWGAGCIMAEMWTRSPIM 229 HSP 2 Score: 60.8474 bits (146), Expect = 1.575e-9 Identity = 52/128 (40.62%), Postives = 73/128 (57.03%), Query Frame = 3
Query: 762 GESEIHQLKLIINLCGSINEESWPGVSKLEAFKRLERT-NHKRFVRQQLLKVIDCHSAVXXXXXXXXXXXXXXXTADIALMHEFFYEDPPAGDLSDF--SNAGSFYEFLS---------NQKKPNQSK 1109
G +E HQL LI LCGSI E WP V E +++LE KR V+ +L + A+DLIDKLL+LDP +R+ +D AL H+FF+ DP DL ++ S +E+L+ Q+ NQS+
Sbjct: 231 GNTEQHQLALISQLCGSITPEVWPNVDNYELYEKLELVKGQKRKVKDRLKAYVRDPYALDLIDKLLVLDPAQRIDSDDALNHDFFWSDPMPSDLKGMLSTHLTSMFEYLAPPRRKGSQITQQSTNQSR 358
BLAST of Cyclin-dependent kinase 9 vs. Ensembl Human
Match: CDK13 (cyclin dependent kinase 13 [Source:HGNC Symbol;Acc:HGNC:1733]) HSP 1 Score: 206.838 bits (525), Expect = 7.234e-64 Identity = 101/217 (46.54%), Postives = 147/217 (67.74%), Query Frame = 1
Query: 118 VDQYEKLQKIGQGTFGEVFKVRDIQTKKYYALKRIKLEQEKEGFPITALREIKILQSLNHPNIVCLREICC--SSPTKEKLYKPEFYLLFDLCDHDLAGLLSDQNMKFSLPQRKSIMKQLFTGIFYLHRNNVIHRDLKAANILIEKHGTLKIADFGLAR-YTIKSPKPDHPPKYTSRVVTMWYRPPEILLNDRHYDKSVDMWGAGCIMAELWTKYPI 759
VD+++ + IG+GT+G+V+K RD T + ALK+++L+ EKEGFPITA+REIKIL+ L H +I+ ++EI K K FYL+F+ DHDL GLL + F+ KS M+QL G+ Y H+ N +HRD+K +NIL+ G +K+ADFGLAR Y+ + +P YT++V+T+WYRPPE+LL + Y ++D+W GCI+ EL+TK PI
Sbjct: 12 VDKFDIIGIIGEGTYGQVYKARDKDTGEMVALKKVRLDNEKEGFPITAIREIKILRQLTHQSIINMKEIVTDKEDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFNENHIKSFMRQLMEGLDYCHKKNFLHRDIKCSNILLNNRGQIKLADFGLARLYSSEESRP-----YTNKVITLWYRPPELLLGEERYTPAIDVWSCGCILGELFTKKPI 223
BLAST of Cyclin-dependent kinase 9 vs. Ensembl Human
Match: CDK13 (cyclin dependent kinase 13 [Source:HGNC Symbol;Acc:HGNC:1733]) HSP 1 Score: 206.068 bits (523), Expect = 1.787e-62 Identity = 101/217 (46.54%), Postives = 147/217 (67.74%), Query Frame = 1
Query: 118 VDQYEKLQKIGQGTFGEVFKVRDIQTKKYYALKRIKLEQEKEGFPITALREIKILQSLNHPNIVCLREICCSSPTKE--KLYKPEFYLLFDLCDHDLAGLLSDQNMKFSLPQRKSIMKQLFTGIFYLHRNNVIHRDLKAANILIEKHGTLKIADFGLAR-YTIKSPKPDHPPKYTSRVVTMWYRPPEILLNDRHYDKSVDMWGAGCIMAELWTKYPI 759
VD+++ + IG+GT+G+V+K RD T + ALK+++L+ EKEGFPITA+REIKIL+ L H +I+ ++EI K K FYL+F+ DHDL GLL + F+ KS M+QL G+ Y H+ N +HRD+K +NIL+ G +K+ADFGLAR Y+ + +P YT++V+T+WYRPPE+LL + Y ++D+W GCI+ EL+TK PI
Sbjct: 88 VDKFDIIGIIGEGTYGQVYKARDKDTGEMVALKKVRLDNEKEGFPITAIREIKILRQLTHQSIINMKEIVTDKEDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFNENHIKSFMRQLMEGLDYCHKKNFLHRDIKCSNILLNNRGQIKLADFGLARLYSSEESRP-----YTNKVITLWYRPPELLLGEERYTPAIDVWSCGCILGELFTKKPI 299
BLAST of Cyclin-dependent kinase 9 vs. Ensembl Human
Match: CDK13 (cyclin dependent kinase 13 [Source:HGNC Symbol;Acc:HGNC:1733]) HSP 1 Score: 208.379 bits (529), Expect = 7.268e-62 Identity = 101/217 (46.54%), Postives = 147/217 (67.74%), Query Frame = 1
Query: 118 VDQYEKLQKIGQGTFGEVFKVRDIQTKKYYALKRIKLEQEKEGFPITALREIKILQSLNHPNIVCLREICCSSPTKE--KLYKPEFYLLFDLCDHDLAGLLSDQNMKFSLPQRKSIMKQLFTGIFYLHRNNVIHRDLKAANILIEKHGTLKIADFGLAR-YTIKSPKPDHPPKYTSRVVTMWYRPPEILLNDRHYDKSVDMWGAGCIMAELWTKYPI 759
VD+++ + IG+GT+G+V+K RD T + ALK+++L+ EKEGFPITA+REIKIL+ L H +I+ ++EI K K FYL+F+ DHDL GLL + F+ KS M+QL G+ Y H+ N +HRD+K +NIL+ G +K+ADFGLAR Y+ + +P YT++V+T+WYRPPE+LL + Y ++D+W GCI+ EL+TK PI
Sbjct: 220 VDKFDIIGIIGEGTYGQVYKARDKDTGEMVALKKVRLDNEKEGFPITAIREIKILRQLTHQSIINMKEIVTDKEDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFNENHIKSFMRQLMEGLDYCHKKNFLHRDIKCSNILLNNRGQIKLADFGLARLYSSEESRP-----YTNKVITLWYRPPELLLGEERYTPAIDVWSCGCILGELFTKKPI 431
BLAST of Cyclin-dependent kinase 9 vs. Ensembl Human
Match: CDK13 (cyclin dependent kinase 13 [Source:HGNC Symbol;Acc:HGNC:1733]) HSP 1 Score: 205.297 bits (521), Expect = 4.547e-61 Identity = 101/217 (46.54%), Postives = 147/217 (67.74%), Query Frame = 1
Query: 118 VDQYEKLQKIGQGTFGEVFKVRDIQTKKYYALKRIKLEQEKEGFPITALREIKILQSLNHPNIVCLREICCSSPTKE--KLYKPEFYLLFDLCDHDLAGLLSDQNMKFSLPQRKSIMKQLFTGIFYLHRNNVIHRDLKAANILIEKHGTLKIADFGLAR-YTIKSPKPDHPPKYTSRVVTMWYRPPEILLNDRHYDKSVDMWGAGCIMAELWTKYPI 759
VD+++ + IG+GT+G+V+K RD T + ALK+++L+ EKEGFPITA+REIKIL+ L H +I+ ++EI K K FYL+F+ DHDL GLL + F+ KS M+QL G+ Y H+ N +HRD+K +NIL+ G +K+ADFGLAR Y+ + +P YT++V+T+WYRPPE+LL + Y ++D+W GCI+ EL+TK PI
Sbjct: 88 VDKFDIIGIIGEGTYGQVYKARDKDTGEMVALKKVRLDNEKEGFPITAIREIKILRQLTHQSIINMKEIVTDKEDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFNENHIKSFMRQLMEGLDYCHKKNFLHRDIKCSNILLNNRGQIKLADFGLARLYSSEESRP-----YTNKVITLWYRPPELLLGEERYTPAIDVWSCGCILGELFTKKPI 299
BLAST of Cyclin-dependent kinase 9 vs. Ensembl Celegans
Match: cdk-9 (Probable cyclin-dependent kinase 9 [Source:UniProtKB/Swiss-Prot;Acc:Q9TVL3]) HSP 1 Score: 258.455 bits (659), Expect = 1.601e-81 Identity = 125/221 (56.56%), Postives = 159/221 (71.95%), Query Frame = 1
Query: 109 LKHVDQYEKLQKIGQGTFGEVFKVRDIQTKKYYALKRIKLEQEKEGFPITALREIKILQSLNHPNIVCLREICC--SSPTKEKLYKPEFYLLFDLCDHDLAGLLSDQNMKFSLPQRKSIMKQLFTGIFYLHRNNVIHRDLKAANILIEKHGTLKIADFGLARYTIKSPKPDHP-PKYTSRVVTMWYRPPEILLNDRHYDKSVDMWGAGCIMAELWTKYPIM 762
++ V YEKL KIGQGTFGEVFK R T + ALK+I +E EKEGFPITALRE+K+L+ L HPNI L E+C S+ T + FYL+ LC HDLAGLLS+ ++ SL K++MK L +G+ LHR+ ++HRD+KAAN+LI K G LK+ADFGLAR ++ P P YT+RVVT+WYRPPE+LL DR Y +D+WGAGCIMAE+WT+ PIM
Sbjct: 79 IRDVSTYEKLNKIGQGTFGEVFKARCKNTGRMVALKKILMENEKEGFPITALREVKMLEQLKHPNITDLIEVCSAKSTGTTGSKDRATFYLVMALCAHDLAGLLSNPKIRMSLVHIKTMMKHLMSGLNKLHRSKILHRDMKAANVLISKDGILKLADFGLARPFVQRENGAGPRPLYTNRVVTLWYRPPELLLGDRQYGTKIDVWGAGCIMAEMWTRQPIM 299
BLAST of Cyclin-dependent kinase 9 vs. Ensembl Celegans
Match: cdk-9 (Probable cyclin-dependent kinase 9 [Source:UniProtKB/Swiss-Prot;Acc:Q9TVL3]) HSP 1 Score: 258.455 bits (659), Expect = 3.240e-81 Identity = 125/221 (56.56%), Postives = 159/221 (71.95%), Query Frame = 1
Query: 109 LKHVDQYEKLQKIGQGTFGEVFKVRDIQTKKYYALKRIKLEQEKEGFPITALREIKILQSLNHPNIVCLREICC--SSPTKEKLYKPEFYLLFDLCDHDLAGLLSDQNMKFSLPQRKSIMKQLFTGIFYLHRNNVIHRDLKAANILIEKHGTLKIADFGLARYTIKSPKPDHP-PKYTSRVVTMWYRPPEILLNDRHYDKSVDMWGAGCIMAELWTKYPIM 762
++ V YEKL KIGQGTFGEVFK R T + ALK+I +E EKEGFPITALRE+K+L+ L HPNI L E+C S+ T + FYL+ LC HDLAGLLS+ ++ SL K++MK L +G+ LHR+ ++HRD+KAAN+LI K G LK+ADFGLAR ++ P P YT+RVVT+WYRPPE+LL DR Y +D+WGAGCIMAE+WT+ PIM
Sbjct: 79 IRDVSTYEKLNKIGQGTFGEVFKARCKNTGRMVALKKILMENEKEGFPITALREVKMLEQLKHPNITDLIEVCSAKSTGTTGSKDRATFYLVMALCAHDLAGLLSNPKIRMSLVHIKTMMKHLMSGLNKLHRSKILHRDMKAANVLISKDGILKLADFGLARPFVQRENGAGPRPLYTNRVVTLWYRPPELLLGDRQYGTKIDVWGAGCIMAEMWTRQPIM 299
BLAST of Cyclin-dependent kinase 9 vs. Ensembl Celegans
Match: cdk-12 (Cyclin-dependent kinase 12 [Source:UniProtKB/Swiss-Prot;Acc:P46551]) HSP 1 Score: 200.29 bits (508), Expect = 4.076e-57 Identity = 102/227 (44.93%), Postives = 147/227 (64.76%), Query Frame = 1
Query: 88 SDPNLSVLKHVDQYEKLQKIGQGTFGEVFKVRDIQTKKYYALKRIKLEQEKEGFPITALREIKILQSLNHPNIVCLREICCSSPTKEKL--YKPEFYLLFDLCDHDLAGLLSDQNM-KFSLPQRKSIMKQLFTGIFYLHRNNVIHRDLKAANILIEKHGTLKIADFGLARYTIKSPKPDHPPKYTSRVVTMWYRPPEILLNDRHYDKSVDMWGAGCIMAELWTKYPI 759
SD + ++ Y L +IG+GT+G+V+K + T + ALKR++LE EKEGFPITA+REIKIL+ L+H NIV L +I + ++L + FYL+F+ DHDL GLL + + F+ Q S+ KQL G+ Y+H +HRD+K +NIL+ G LKIAD GLAR K + YT+RV+T+WYRPPE+LL D Y ++D+W GC++ EL+T+ P+
Sbjct: 298 SDSDSWYKTNLTHYTMLDQIGEGTYGQVYKAVNNLTGEQVALKRVRLENEKEGFPITAIREIKILRQLHHKNIVRLMDIVIDDISMDELKRTRANFYLVFEYVDHDLIGLLESKELVDFNKDQICSLFKQLLEGLAYIHNTGFLHRDIKCSNILVNNKGELKIADLGLARLWEKESR-----LYTNRVITLWYRPPELLLGDERYGPAIDVWSTGCMLGELFTRKPL 519
BLAST of Cyclin-dependent kinase 9 vs. Ensembl Celegans
Match: cdk-12 (Cyclin-dependent kinase 12 [Source:UniProtKB/Swiss-Prot;Acc:P46551]) HSP 1 Score: 200.29 bits (508), Expect = 4.125e-57 Identity = 102/227 (44.93%), Postives = 147/227 (64.76%), Query Frame = 1
Query: 88 SDPNLSVLKHVDQYEKLQKIGQGTFGEVFKVRDIQTKKYYALKRIKLEQEKEGFPITALREIKILQSLNHPNIVCLREICCSSPTKEKL--YKPEFYLLFDLCDHDLAGLLSDQNM-KFSLPQRKSIMKQLFTGIFYLHRNNVIHRDLKAANILIEKHGTLKIADFGLARYTIKSPKPDHPPKYTSRVVTMWYRPPEILLNDRHYDKSVDMWGAGCIMAELWTKYPI 759
SD + ++ Y L +IG+GT+G+V+K + T + ALKR++LE EKEGFPITA+REIKIL+ L+H NIV L +I + ++L + FYL+F+ DHDL GLL + + F+ Q S+ KQL G+ Y+H +HRD+K +NIL+ G LKIAD GLAR K + YT+RV+T+WYRPPE+LL D Y ++D+W GC++ EL+T+ P+
Sbjct: 298 SDSDSWYKTNLTHYTMLDQIGEGTYGQVYKAVNNLTGEQVALKRVRLENEKEGFPITAIREIKILRQLHHKNIVRLMDIVIDDISMDELKRTRANFYLVFEYVDHDLIGLLESKELVDFNKDQICSLFKQLLEGLAYIHNTGFLHRDIKCSNILVNNKGELKIADLGLARLWEKESR-----LYTNRVITLWYRPPELLLGDERYGPAIDVWSTGCMLGELFTRKPL 519
BLAST of Cyclin-dependent kinase 9 vs. Ensembl Celegans
Match: cdk-12 (Cyclin-dependent kinase 12 [Source:UniProtKB/Swiss-Prot;Acc:P46551]) HSP 1 Score: 200.29 bits (508), Expect = 4.452e-57 Identity = 102/227 (44.93%), Postives = 147/227 (64.76%), Query Frame = 1
Query: 88 SDPNLSVLKHVDQYEKLQKIGQGTFGEVFKVRDIQTKKYYALKRIKLEQEKEGFPITALREIKILQSLNHPNIVCLREICCSSPTKEKL--YKPEFYLLFDLCDHDLAGLLSDQNM-KFSLPQRKSIMKQLFTGIFYLHRNNVIHRDLKAANILIEKHGTLKIADFGLARYTIKSPKPDHPPKYTSRVVTMWYRPPEILLNDRHYDKSVDMWGAGCIMAELWTKYPI 759
SD + ++ Y L +IG+GT+G+V+K + T + ALKR++LE EKEGFPITA+REIKIL+ L+H NIV L +I + ++L + FYL+F+ DHDL GLL + + F+ Q S+ KQL G+ Y+H +HRD+K +NIL+ G LKIAD GLAR K + YT+RV+T+WYRPPE+LL D Y ++D+W GC++ EL+T+ P+
Sbjct: 298 SDSDSWYKTNLTHYTMLDQIGEGTYGQVYKAVNNLTGEQVALKRVRLENEKEGFPITAIREIKILRQLHHKNIVRLMDIVIDDISMDELKRTRANFYLVFEYVDHDLIGLLESKELVDFNKDQICSLFKQLLEGLAYIHNTGFLHRDIKCSNILVNNKGELKIADLGLARLWEKESR-----LYTNRVITLWYRPPELLLGDERYGPAIDVWSTGCMLGELFTRKPL 519
BLAST of Cyclin-dependent kinase 9 vs. Ensembl Fly
Match: Cdk9 (gene:FBgn0019949 transcript:FBtr0071937) HSP 1 Score: 281.952 bits (720), Expect = 4.150e-91 Identity = 130/215 (60.47%), Postives = 168/215 (78.14%), Query Frame = 1
Query: 121 DQYEKLQKIGQGTFGEVFKVRDIQ-TKKYYALKRIKLEQEKEGFPITALREIKILQSLNHPNIVCLREICCSSPTKEKLYKPEFYLLFDLCDHDLAGLLSDQNMKFSLPQRKSIMKQLFTGIFYLHRNNVIHRDLKAANILIEKHGTLKIADFGLARYTIKSPKPDHPPKYTSRVVTMWYRPPEILLNDRHYDKSVDMWGAGCIMAELWTKYPIM 762
++YEK+ KIGQGTFGEVFK R+ + KK+ A+K++ ++ EKEGFPITALREI+ILQ L H N+V L EIC + T Y+ FYL+FD C+HDLAGLLS+ N+KFSL + K +M+QL G++Y+H N ++HRD+KAAN+LI KHG LK+ADFGLAR PK + +YT+RVVT+WYRPPE+LL DR+Y VDMWGAGCIMAE+WT+ PIM
Sbjct: 48 NKYEKVAKIGQGTFGEVFKAREKKGNKKFVAMKKVLMDNEKEGFPITALREIRILQLLKHENVVNLIEICRTKATATNGYRSTFYLVFDFCEHDLAGLLSNMNVKFSLGEIKKVMQQLLNGLYYIHSNKILHRDMKAANVLITKHGILKLADFGLAR-AFSIPKNESKNRYTNRVVTLWYRPPELLLGDRNYGPPVDMWGAGCIMAEMWTRSPIM 261 HSP 2 Score: 71.633 bits (174), Expect = 3.199e-13 Identity = 53/142 (37.32%), Postives = 82/142 (57.75%), Query Frame = 3
Query: 762 GESEIHQLKLIINLCGSINEESWPGVSKLEAFKRLE-RTNHKRFVRQQLLKVIDCHSAVXXXXXXXXXXXXXXXTADIALMHEFFYEDPPAGDLSDF--SNAGSFYEFLSNQKKPNQSKANYLNRDAMKET---SGILDRIY 1169
G +E QL I LCGS + WPGV +LE +K +E N KR V+++L + + DL+DKLL LDP+KR+ AD AL H+FF+ DP DLS + S +E+L+ ++ NQ + + M + + ++DR++
Sbjct: 263 GNTEQQQLTFISQLCGSFTPDVWPGVEELELYKSIELPKNQKRRVKERLRPYVKDQTGCDLLDKLLTLDPKKRIDADTALNHDFFWTDPMPSDLSKMLSQHLQSMFEYLAQPRRSNQMRNYHQQLTTMNQKPQDNSMIDRVW 404
BLAST of Cyclin-dependent kinase 9 vs. Ensembl Fly
Match: Cdk12 (gene:FBgn0037093 transcript:FBtr0078357) HSP 1 Score: 214.542 bits (545), Expect = 6.473e-61 Identity = 106/217 (48.85%), Postives = 143/217 (65.90%), Query Frame = 1
Query: 118 VDQYEKLQKIGQGTFGEVFKVRDIQTKKYYALKRIKLEQEKEGFPITALREIKILQSLNHPNIVCLREICCSSPTKEKLYKPE--FYLLFDLCDHDLAGLLSDQNMKFSLPQRKSIMKQLFTGIFYLHRNNVIHRDLKAANILIEKHGTLKIADFGLAR-YTIKSPKPDHPPKYTSRVVTMWYRPPEILLNDRHYDKSVDMWGAGCIMAELWTKYPI 759
VD +E + +IG+GT+G+V+K RD T ALK+++LE EKEGFPITA+REIKIL+ LNH NIV L EI + K + FYL+F+ DHDL GLL + F+ SIMKQL G+ Y H+ N +HRD+K +NIL+ G +K+ADFGLAR Y D YT++V+T+WYRPPE+LL + Y S+D+W GCI+ EL+ K P+
Sbjct: 801 VDVFEMIAQIGEGTYGQVYKARDHHTNDMVALKKVRLEHEKEGFPITAVREIKILRQLNHRNIVNLHEIVTDKQDAVEFRKDKGSFYLVFEYMDHDLMGLLESGMVDFNEENNASIMKQLLDGLNYCHKKNFLHRDIKCSNILMNNRGKVKLADFGLARLYNAD----DRERPYTNKVITLWYRPPELLLGEERYGPSIDVWSCGCILGELFVKRPL 1013
BLAST of Cyclin-dependent kinase 9 vs. Ensembl Fly
Match: Cdk12 (gene:FBgn0037093 transcript:FBtr0332716) HSP 1 Score: 214.542 bits (545), Expect = 6.473e-61 Identity = 106/217 (48.85%), Postives = 143/217 (65.90%), Query Frame = 1
Query: 118 VDQYEKLQKIGQGTFGEVFKVRDIQTKKYYALKRIKLEQEKEGFPITALREIKILQSLNHPNIVCLREICCSSPTKEKLYKPE--FYLLFDLCDHDLAGLLSDQNMKFSLPQRKSIMKQLFTGIFYLHRNNVIHRDLKAANILIEKHGTLKIADFGLAR-YTIKSPKPDHPPKYTSRVVTMWYRPPEILLNDRHYDKSVDMWGAGCIMAELWTKYPI 759
VD +E + +IG+GT+G+V+K RD T ALK+++LE EKEGFPITA+REIKIL+ LNH NIV L EI + K + FYL+F+ DHDL GLL + F+ SIMKQL G+ Y H+ N +HRD+K +NIL+ G +K+ADFGLAR Y D YT++V+T+WYRPPE+LL + Y S+D+W GCI+ EL+ K P+
Sbjct: 801 VDVFEMIAQIGEGTYGQVYKARDHHTNDMVALKKVRLEHEKEGFPITAVREIKILRQLNHRNIVNLHEIVTDKQDAVEFRKDKGSFYLVFEYMDHDLMGLLESGMVDFNEENNASIMKQLLDGLNYCHKKNFLHRDIKCSNILMNNRGKVKLADFGLARLYNAD----DRERPYTNKVITLWYRPPELLLGEERYGPSIDVWSCGCILGELFVKRPL 1013
BLAST of Cyclin-dependent kinase 9 vs. Ensembl Fly
Match: Cdk12 (gene:FBgn0037093 transcript:FBtr0078358) HSP 1 Score: 214.542 bits (545), Expect = 6.473e-61 Identity = 106/217 (48.85%), Postives = 143/217 (65.90%), Query Frame = 1
Query: 118 VDQYEKLQKIGQGTFGEVFKVRDIQTKKYYALKRIKLEQEKEGFPITALREIKILQSLNHPNIVCLREICCSSPTKEKLYKPE--FYLLFDLCDHDLAGLLSDQNMKFSLPQRKSIMKQLFTGIFYLHRNNVIHRDLKAANILIEKHGTLKIADFGLAR-YTIKSPKPDHPPKYTSRVVTMWYRPPEILLNDRHYDKSVDMWGAGCIMAELWTKYPI 759
VD +E + +IG+GT+G+V+K RD T ALK+++LE EKEGFPITA+REIKIL+ LNH NIV L EI + K + FYL+F+ DHDL GLL + F+ SIMKQL G+ Y H+ N +HRD+K +NIL+ G +K+ADFGLAR Y D YT++V+T+WYRPPE+LL + Y S+D+W GCI+ EL+ K P+
Sbjct: 801 VDVFEMIAQIGEGTYGQVYKARDHHTNDMVALKKVRLEHEKEGFPITAVREIKILRQLNHRNIVNLHEIVTDKQDAVEFRKDKGSFYLVFEYMDHDLMGLLESGMVDFNEENNASIMKQLLDGLNYCHKKNFLHRDIKCSNILMNNRGKVKLADFGLARLYNAD----DRERPYTNKVITLWYRPPELLLGEERYGPSIDVWSCGCILGELFVKRPL 1013
BLAST of Cyclin-dependent kinase 9 vs. Ensembl Fly
Match: Cdk5 (gene:FBgn0013762 transcript:FBtr0087350) HSP 1 Score: 176.022 bits (445), Expect = 1.405e-51 Identity = 93/208 (44.71%), Postives = 133/208 (63.94%), Query Frame = 1
Query: 124 QYEKLQKIGQGTFGEVFKVRDIQTKKYYALKRIKLEQEKEGFPITALREIKILQSLNHPNIVCLREICCSSPTKEKLYKPEFYLLFDLCDHDLAGLLSDQNMKFSLPQRKSIMKQLFTGIFYLHRNNVIHRDLKAANILIEKHGTLKIADFGLAR-YTIKSPKPDHPPK-YTSRVVTMWYRPPEILLNDRHYDKSVDMWGAGCIMAEL 741
+Y+K++KIG+GT+G VFK R+ T + ALKR++L+++ EG P +ALREI +L+ L H NIV L ++ S + L+F+ CD DL N + + +S M QL G+ + H +NV+HRDLK N+LI K+G LK+ADFGLAR + I P K Y++ VVT+WYRPP++L + Y S+DMW AGCI+AEL
Sbjct: 3 KYDKMEKIGEGTYGTVFKGRNRDTMEIVALKRVRLDEDDEGVPSSALREICLLKELKHKNIVRLIDVLHSD--------KKLTLVFEHCDQDLKKYFDSLNGEIDMAVCRSFMLQLLRGLAFCHSHNVLHRDLKPQNLLINKNGELKLADFGLARAFGI-------PVKCYSAEVVTLWYRPPDVLFGAKLYTTSIDMWSAGCILAEL 195
BLAST of Cyclin-dependent kinase 9 vs. Ensembl Zebrafish
Match: cdk9 (cyclin-dependent kinase 9 (CDC2-related kinase) [Source:ZFIN;Acc:ZDB-GENE-030131-321]) HSP 1 Score: 272.322 bits (695), Expect = 2.156e-87 Identity = 127/213 (59.62%), Postives = 161/213 (75.59%), Query Frame = 1
Query: 124 QYEKLQKIGQGTFGEVFKVRDIQTKKYYALKRIKLEQEKEGFPITALREIKILQSLNHPNIVCLREICCSSPTKEKLYKPEFYLLFDLCDHDLAGLLSDQNMKFSLPQRKSIMKQLFTGIFYLHRNNVIHRDLKAANILIEKHGTLKIADFGLARYTIKSPKPDHPPKYTSRVVTMWYRPPEILLNDRHYDKSVDMWGAGCIMAELWTKYPIM 762
+YEKL KIGQGTFGEVFK + QT K ALK++ +E EKEGFPITALREIKILQ L H N+V L EIC + T+ YK YL+FD C+HDLAGLLS+ N+KF+L + K +M+ L G++Y+HRN ++HRD+KAAN+LI + G LK+ADFGLAR K +YT+RVVT+WYRPPE+LL +R Y +D+WGAGCIMAE+WT+ PIM
Sbjct: 39 KYEKLAKIGQGTFGEVFKAKHRQTGKKVALKKVLMENEKEGFPITALREIKILQLLKHENVVNLIEICRTKATQFNRYKGSIYLVFDFCEHDLAGLLSNANVKFTLAEIKRVMQMLLNGLYYIHRNKILHRDMKAANVLITRDGVLKLADFGLAR-AFSLAKNSQGNRYTNRVVTLWYRPPELLLGERDYGPPIDLWGAGCIMAEMWTRSPIM 250 HSP 2 Score: 64.3142 bits (155), Expect = 9.245e-11 Identity = 56/143 (39.16%), Postives = 83/143 (58.04%), Query Frame = 3
Query: 762 GESEIHQLKLIINLCGSINEESWPGV-SKLEAFKRLE-RTNHKRFVRQQLLKVIDCHSAVXXXXXXXXXXXXXXXTADIALMHEFFYEDPPAGDLSDF--SNAGSFYEFLSNQKKPN---QSKANYLNRDAMKETSGILDRIY 1169
G +E HQL LI LCGSI E WPGV K E ++++E KR V+ +L + A+DLIDKLL+LDP +R+ +D AL H+FF+ DP DL + ++ S +E+L+ ++ Q AN NR+ + DR++
Sbjct: 252 GNTEQHQLTLISQLCGSITPEVWPGVDKKYELYQKMELPKGQKRKVKDRLKAYVKDPYALDLIDKLLVLDPAQRIDSDDALNHDFFWSDPMPSDLKNMLSTHNTSMFEYLAPPRRRGHMPQQPANQ-NRNPATTSQSEFDRVF 393
BLAST of Cyclin-dependent kinase 9 vs. Ensembl Zebrafish
Match: cdk9 (cyclin-dependent kinase 9 (CDC2-related kinase) [Source:ZFIN;Acc:ZDB-GENE-030131-321]) HSP 1 Score: 272.322 bits (695), Expect = 2.156e-87 Identity = 127/213 (59.62%), Postives = 161/213 (75.59%), Query Frame = 1
Query: 124 QYEKLQKIGQGTFGEVFKVRDIQTKKYYALKRIKLEQEKEGFPITALREIKILQSLNHPNIVCLREICCSSPTKEKLYKPEFYLLFDLCDHDLAGLLSDQNMKFSLPQRKSIMKQLFTGIFYLHRNNVIHRDLKAANILIEKHGTLKIADFGLARYTIKSPKPDHPPKYTSRVVTMWYRPPEILLNDRHYDKSVDMWGAGCIMAELWTKYPIM 762
+YEKL KIGQGTFGEVFK + QT K ALK++ +E EKEGFPITALREIKILQ L H N+V L EIC + T+ YK YL+FD C+HDLAGLLS+ N+KF+L + K +M+ L G++Y+HRN ++HRD+KAAN+LI + G LK+ADFGLAR K +YT+RVVT+WYRPPE+LL +R Y +D+WGAGCIMAE+WT+ PIM
Sbjct: 39 KYEKLAKIGQGTFGEVFKAKHRQTGKKVALKKVLMENEKEGFPITALREIKILQLLKHENVVNLIEICRTKATQFNRYKGSIYLVFDFCEHDLAGLLSNANVKFTLAEIKRVMQMLLNGLYYIHRNKILHRDMKAANVLITRDGVLKLADFGLAR-AFSLAKNSQGNRYTNRVVTLWYRPPELLLGERDYGPPIDLWGAGCIMAEMWTRSPIM 250 HSP 2 Score: 64.3142 bits (155), Expect = 9.245e-11 Identity = 56/143 (39.16%), Postives = 83/143 (58.04%), Query Frame = 3
Query: 762 GESEIHQLKLIINLCGSINEESWPGV-SKLEAFKRLE-RTNHKRFVRQQLLKVIDCHSAVXXXXXXXXXXXXXXXTADIALMHEFFYEDPPAGDLSDF--SNAGSFYEFLSNQKKPN---QSKANYLNRDAMKETSGILDRIY 1169
G +E HQL LI LCGSI E WPGV K E ++++E KR V+ +L + A+DLIDKLL+LDP +R+ +D AL H+FF+ DP DL + ++ S +E+L+ ++ Q AN NR+ + DR++
Sbjct: 252 GNTEQHQLTLISQLCGSITPEVWPGVDKKYELYQKMELPKGQKRKVKDRLKAYVKDPYALDLIDKLLVLDPAQRIDSDDALNHDFFWSDPMPSDLKNMLSTHNTSMFEYLAPPRRRGHMPQQPANQ-NRNPATTSQSEFDRVF 393
BLAST of Cyclin-dependent kinase 9 vs. Ensembl Zebrafish
Match: cdk9 (cyclin-dependent kinase 9 (CDC2-related kinase) [Source:ZFIN;Acc:ZDB-GENE-030131-321]) HSP 1 Score: 266.929 bits (681), Expect = 1.380e-85 Identity = 127/215 (59.07%), Postives = 161/215 (74.88%), Query Frame = 1
Query: 124 QYEKLQKIGQGTFGEVFKVRDIQTKKYYALKRIKLEQEKEGFPITALREIKILQSLNHPNIVCLREICCS--SPTKEKLYKPEFYLLFDLCDHDLAGLLSDQNMKFSLPQRKSIMKQLFTGIFYLHRNNVIHRDLKAANILIEKHGTLKIADFGLARYTIKSPKPDHPPKYTSRVVTMWYRPPEILLNDRHYDKSVDMWGAGCIMAELWTKYPIM 762
+YEKL KIGQGTFGEVFK + QT K ALK++ +E EKEGFPITALREIKILQ L H N+V L EIC + T+ YK YL+FD C+HDLAGLLS+ N+KF+L + K +M+ L G++Y+HRN ++HRD+KAAN+LI + G LK+ADFGLAR K +YT+RVVT+WYRPPE+LL +R Y +D+WGAGCIMAE+WT+ PIM
Sbjct: 18 KYEKLAKIGQGTFGEVFKAKHRQTGKKVALKKVLMENEKEGFPITALREIKILQLLKHENVVNLIEICRTKGEATQFNRYKGSIYLVFDFCEHDLAGLLSNANVKFTLAEIKRVMQMLLNGLYYIHRNKILHRDMKAANVLITRDGVLKLADFGLAR-AFSLAKNSQGNRYTNRVVTLWYRPPELLLGERDYGPPIDLWGAGCIMAEMWTRSPIM 231 HSP 2 Score: 63.929 bits (154), Expect = 1.044e-10 Identity = 56/143 (39.16%), Postives = 83/143 (58.04%), Query Frame = 3
Query: 762 GESEIHQLKLIINLCGSINEESWPGV-SKLEAFKRLE-RTNHKRFVRQQLLKVIDCHSAVXXXXXXXXXXXXXXXTADIALMHEFFYEDPPAGDLSDF--SNAGSFYEFLSNQKKPN---QSKANYLNRDAMKETSGILDRIY 1169
G +E HQL LI LCGSI E WPGV K E ++++E KR V+ +L + A+DLIDKLL+LDP +R+ +D AL H+FF+ DP DL + ++ S +E+L+ ++ Q AN NR+ + DR++
Sbjct: 233 GNTEQHQLTLISQLCGSITPEVWPGVDKKYELYQKMELPKGQKRKVKDRLKAYVKDPYALDLIDKLLVLDPAQRIDSDDALNHDFFWSDPMPSDLKNMLSTHNTSMFEYLAPPRRRGHMPQQPANQ-NRNPATTSQSEFDRVF 374
BLAST of Cyclin-dependent kinase 9 vs. Ensembl Zebrafish
Match: cdk12 (cyclin-dependent kinase 12 [Source:ZFIN;Acc:ZDB-GENE-081104-294]) HSP 1 Score: 207.608 bits (527), Expect = 2.364e-58 Identity = 100/217 (46.08%), Postives = 147/217 (67.74%), Query Frame = 1
Query: 118 VDQYEKLQKIGQGTFGEVFKVRDIQTKKYYALKRIKLEQEKEGFPITALREIKILQSLNHPNIVCLREICCSSPTKEKLYKPE--FYLLFDLCDHDLAGLLSDQNMKFSLPQRKSIMKQLFTGIFYLHRNNVIHRDLKAANILIEKHGTLKIADFGLAR-YTIKSPKPDHPPKYTSRVVTMWYRPPEILLNDRHYDKSVDMWGAGCIMAELWTKYPI 759
VD+++ + IG+GT+G+V+K +D T + ALK+++L+ EKEGFPITA+REIKIL+ LNH ++V ++EI K + FYL+F+ DHDL GLL + FS +S M+QL G+ Y H+ N +HRD+K +NIL+ G +K+ADFGLAR Y + +P YT++V+T+WYRPPE+LL + Y ++D+W GCI+ EL+TK PI
Sbjct: 672 VDKFDIIGIIGEGTYGQVYKAKDKDTGELVALKKVRLDNEKEGFPITAIREIKILRQLNHRSVVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVSFSHEHVQSFMRQLMEGLDYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSEESRP-----YTNKVITLWYRPPELLLGEERYSPAIDVWSCGCILGELFTKKPI 883
BLAST of Cyclin-dependent kinase 9 vs. Ensembl Zebrafish
Match: cdk13 (cyclin-dependent kinase 13 [Source:ZFIN;Acc:ZDB-GENE-030131-4975]) HSP 1 Score: 207.223 bits (526), Expect = 3.949e-58 Identity = 103/220 (46.82%), Postives = 148/220 (67.27%), Query Frame = 1
Query: 118 VDQYEKLQKIGQGTFGEVFKVRDIQTKKYYALKRIKLEQEKEGFPITALREIKILQSLNHPNIVCLREICCSSPTKE-----KLYKPEFYLLFDLCDHDLAGLLSDQNMKFSLPQRKSIMKQLFTGIFYLHRNNVIHRDLKAANILIEKHGTLKIADFGLAR-YTIKSPKPDHPPKYTSRVVTMWYRPPEILLNDRHYDKSVDMWGAGCIMAELWTKYPI 759
VD++E + G+GT+G+V+K +D T + ALK+++L+ EKEGFPITA+REIKIL+ LNH +I+ ++EI KE K K FYL+F+ DHDL GLL + F+ KS M+QL G+ Y H+ N +HRD+K +NIL+ G +K+ADFGLAR Y + +P YT++V+T+WYRPPE+LL + Y ++D+W GCI+ EL+TK PI
Sbjct: 591 VDKFEIIGITGEGTYGQVYKAKDKDTAELVALKKVRLDNEKEGFPITAIREIKILRQLNHKSIINMKEIVTD---KEDALDFKNDKGAFYLVFEYMDHDLMGLLESGLVHFNESHIKSFMRQLLEGLDYCHKKNFLHRDIKCSNILLNNKGQIKLADFGLARLYNSEESRP-----YTNKVITLWYRPPELLLGEERYTPAIDVWSCGCILGELFTKKPI 802
BLAST of Cyclin-dependent kinase 9 vs. Ensembl Xenopus
Match: slc4a3 (solute carrier family 4 (anion exchanger), member 3 [Source:Xenbase;Acc:XB-GENE-996901]) HSP 1 Score: 265.774 bits (678), Expect = 4.049e-84 Identity = 128/220 (58.18%), Postives = 164/220 (74.55%), Query Frame = 1
Query: 115 HVDQYEKLQKIGQGTFGEVFKVRDIQTKKYYALKRIKLEQEKEGFPITALREIKILQSLNHPNIVCLREICCS--SPTKEKLY--KPEFYLLFDLCDHDLAGLLSDQNMKFSLPQRKSIMKQLFTGIFYLHRNNVIHRDLKAANILIEKHGTLKIADFGLARYTIKSPKPDHPPKYTSRVVTMWYRPPEILLNDRHYDKSVDMWGAGCIMAELWTKYPIM 762
V +YE+L KIGQGTFGEVFK + QT K ALK++ +E EKEGFPITALREIKILQ L H N+V L EIC + SPT + K +L+FD C+HDLAGLLS+ ++KF+L + K +M+ L G++Y+HRN ++HRD+KAAN+LI + G LK+ADFGLAR K P KYT+RVVT+WYRPPE+LL +R Y +D+WGAGCIMAE+WT+ PIM
Sbjct: 74 EVSKYERLAKIGQGTFGEVFKAKHRQTGKKVALKKVLMENEKEGFPITALREIKILQLLKHENVVNLIEICRTKISPTANQYNRCKGTIFLVFDFCEHDLAGLLSNAHVKFTLSEIKKVMQMLLNGLYYIHRNKILHRDMKAANVLITRDGVLKLADFGLAR-AFSLAKNSQPNKYTNRVVTLWYRPPELLLGERDYGPPIDLWGAGCIMAEMWTRSPIM 292 HSP 2 Score: 64.6994 bits (156), Expect = 1.120e-10 Identity = 55/144 (38.19%), Postives = 82/144 (56.94%), Query Frame = 3
Query: 762 GESEIHQLKLIINLCGSINEESWPGVSKLEAFKRLE-RTNHKRFVRQQLLKVIDCHSAVXXXXXXXXXXXXXXXTADIALMHEFFYEDPPAGDLSDF--SNAGSFYEFLSNQKK-----PNQSKANYLNRDAMKETSGILDRIY 1169
G +E HQL LI LCGSI E WP V K E +++LE KR V+++L + A+DLIDKLL+LDP +R+ +D AL H+FF+ DP DL + ++ S +E+L+ ++ P Q N A ++ DR++
Sbjct: 294 GNTEQHQLTLISQLCGSITPEVWPNVDKYELYQKLELPKGQKRKVKERLKAYVKDLYALDLIDKLLVLDPAQRIDSDDALNHDFFWSDPMPSDLKNMLSTHNQSMFEYLAPPRRRGGHMPQQPANQARNPAATNQSE--FDRVF 435
BLAST of Cyclin-dependent kinase 9 vs. Ensembl Xenopus
Match: cdk12 (cyclin-dependent kinase 12 [Source:NCBI gene;Acc:100038049]) HSP 1 Score: 204.912 bits (520), Expect = 1.111e-60 Identity = 102/217 (47.00%), Postives = 148/217 (68.20%), Query Frame = 1
Query: 118 VDQYEKLQKIGQGTFGEVFKVRDIQTKKYYALKRIKLEQEKEGFPITALREIKILQSLNHPNIVCLREICCS--SPTKEKLYKPEFYLLFDLCDHDLAGLLSDQNMKFSLPQRKSIMKQLFTGIFYLHRNNVIHRDLKAANILIEKHGTLKIADFGLAR-YTIKSPKPDHPPKYTSRVVTMWYRPPEILLNDRHYDKSVDMWGAGCIMAELWTKYPI 759
VD+++ + IG+GT+G+V+K +D T + ALK+++L+ EKEGFPITA+REIKIL+ L H ++V ++EI K K FYL+F+ DHDL GLL ++FS KS MKQL G+ Y H+ N +HRD+K +NIL+ G +K+ADFGLAR Y+ + +P YT++V+T+WYRPPE+LL + Y ++D+W GCI+ EL+TK PI
Sbjct: 95 VDKFDIIGIIGEGTYGQVYKAKDKDTGELVALKKVRLDNEKEGFPITAIREIKILRQLIHKSVVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVQFSEDHIKSFMKQLMEGLEYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYSSEESRP-----YTNKVITLWYRPPELLLGEERYTPAIDVWSCGCILGELFTKKPI 306
BLAST of Cyclin-dependent kinase 9 vs. Ensembl Xenopus
Match: cdk12 (cyclin-dependent kinase 12 [Source:NCBI gene;Acc:100038049]) HSP 1 Score: 207.223 bits (526), Expect = 2.022e-58 Identity = 102/217 (47.00%), Postives = 148/217 (68.20%), Query Frame = 1
Query: 118 VDQYEKLQKIGQGTFGEVFKVRDIQTKKYYALKRIKLEQEKEGFPITALREIKILQSLNHPNIVCLREICCSSPTKE--KLYKPEFYLLFDLCDHDLAGLLSDQNMKFSLPQRKSIMKQLFTGIFYLHRNNVIHRDLKAANILIEKHGTLKIADFGLAR-YTIKSPKPDHPPKYTSRVVTMWYRPPEILLNDRHYDKSVDMWGAGCIMAELWTKYPI 759
VD+++ + IG+GT+G+V+K +D T + ALK+++L+ EKEGFPITA+REIKIL+ L H ++V ++EI K K FYL+F+ DHDL GLL ++FS KS MKQL G+ Y H+ N +HRD+K +NIL+ G +K+ADFGLAR Y+ + +P YT++V+T+WYRPPE+LL + Y ++D+W GCI+ EL+TK PI
Sbjct: 431 VDKFDIIGIIGEGTYGQVYKAKDKDTGELVALKKVRLDNEKEGFPITAIREIKILRQLIHKSVVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVQFSEDHIKSFMKQLMEGLEYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYSSEESRP-----YTNKVITLWYRPPELLLGEERYTPAIDVWSCGCILGELFTKKPI 642
BLAST of Cyclin-dependent kinase 9 vs. Ensembl Xenopus
Match: ankrd2 (ankyrin repeat domain 2 (stretch responsive muscle) [Source:Xenbase;Acc:XB-GENE-1016694]) HSP 1 Score: 207.994 bits (528), Expect = 2.343e-58 Identity = 103/220 (46.82%), Postives = 150/220 (68.18%), Query Frame = 1
Query: 118 VDQYEKLQKIGQGTFGEVFKVRDIQTKKYYALKRIKLEQEKEGFPITALREIKILQSLNHPNIVCLREICCSSPTKE-----KLYKPEFYLLFDLCDHDLAGLLSDQNMKFSLPQRKSIMKQLFTGIFYLHRNNVIHRDLKAANILIEKHGTLKIADFGLAR-YTIKSPKPDHPPKYTSRVVTMWYRPPEILLNDRHYDKSVDMWGAGCIMAELWTKYPI 759
VD+++ + IG+GT+G+V+K +D T + ALK+++L+ EKEGFPITA+REIKIL+ LNH +I+ ++EI KE K K FYL+F+ DHDL GLL + F+ KS M+QL G+ Y H+ N +HRD+K +NIL+ G +K+ADFGLAR Y+ + +P YT++V+T+WYRPPE+LL + Y ++D+W GCI+ EL+TK PI
Sbjct: 380 VDKFDIIGIIGEGTYGQVYKAKDKDTGEMVALKKVRLDNEKEGFPITAIREIKILRQLNHQSIINMKEIVTD---KEDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFNEHHIKSFMRQLMEGLDYCHKRNFLHRDIKCSNILLNNRGQIKLADFGLARLYSSEESRP-----YTNKVITLWYRPPELLLGEERYSPAIDVWSCGCILGELFTKKPI 591
BLAST of Cyclin-dependent kinase 9 vs. Ensembl Xenopus
Match: ankrd2 (ankyrin repeat domain 2 (stretch responsive muscle) [Source:Xenbase;Acc:XB-GENE-1016694]) HSP 1 Score: 207.994 bits (528), Expect = 2.358e-58 Identity = 103/220 (46.82%), Postives = 150/220 (68.18%), Query Frame = 1
Query: 118 VDQYEKLQKIGQGTFGEVFKVRDIQTKKYYALKRIKLEQEKEGFPITALREIKILQSLNHPNIVCLREICCSSPTKE-----KLYKPEFYLLFDLCDHDLAGLLSDQNMKFSLPQRKSIMKQLFTGIFYLHRNNVIHRDLKAANILIEKHGTLKIADFGLAR-YTIKSPKPDHPPKYTSRVVTMWYRPPEILLNDRHYDKSVDMWGAGCIMAELWTKYPI 759
VD+++ + IG+GT+G+V+K +D T + ALK+++L+ EKEGFPITA+REIKIL+ LNH +I+ ++EI KE K K FYL+F+ DHDL GLL + F+ KS M+QL G+ Y H+ N +HRD+K +NIL+ G +K+ADFGLAR Y+ + +P YT++V+T+WYRPPE+LL + Y ++D+W GCI+ EL+TK PI
Sbjct: 595 VDKFDIIGIIGEGTYGQVYKAKDKDTGEMVALKKVRLDNEKEGFPITAIREIKILRQLNHQSIINMKEIVTD---KEDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFNEHHIKSFMRQLMEGLDYCHKRNFLHRDIKCSNILLNNRGQIKLADFGLARLYSSEESRP-----YTNKVITLWYRPPELLLGEERYSPAIDVWSCGCILGELFTKKPI 806
BLAST of Cyclin-dependent kinase 9 vs. Ensembl Mouse
Match: Cdk9 (cyclin-dependent kinase 9 (CDC2-related kinase) [Source:MGI Symbol;Acc:MGI:1328368]) HSP 1 Score: 266.159 bits (679), Expect = 2.981e-85 Identity = 125/216 (57.87%), Postives = 160/216 (74.07%), Query Frame = 1
Query: 115 HVDQYEKLQKIGQGTFGEVFKVRDIQTKKYYALKRIKLEQEKEGFPITALREIKILQSLNHPNIVCLREICCSSPTKEKLYKPEFYLLFDLCDHDLAGLLSDQNMKFSLPQRKSIMKQLFTGIFYLHRNNVIHRDLKAANILIEKHGTLKIADFGLARYTIKSPKPDHPPKYTSRVVTMWYRPPEILLNDRHYDKSVDMWGAGCIMAELWTKYPIM 762
V +YEKL KIGQGTFGEVFK + QT + ALK++ +E EKEGFPITALREIKILQ L H N+V L EIC + + K YL+FD C+HDLAGLLS+ +KF+L + K +M+ L G++Y+HRN ++HRD+KAAN+LI + G LK+ADFGLAR K P +YT+RVVT+WYRPPE+LL +R Y +D+WGAGCIMAE+WT+ PIM
Sbjct: 15 EVTKYEKLAKIGQGTFGEVFKAKHRQTGQKVALKKVLMENEKEGFPITALREIKILQLLKHENVVNLIEICRTKASPYNRCKGSIYLVFDFCEHDLAGLLSNVLVKFTLSEIKRVMQMLLNGLYYIHRNKILHRDMKAANVLITRDGVLKLADFGLAR-AFSLAKNSQPNRYTNRVVTLWYRPPELLLGERDYGPPIDLWGAGCIMAEMWTRSPIM 229 HSP 2 Score: 63.929 bits (154), Expect = 1.118e-10 Identity = 54/128 (42.19%), Postives = 74/128 (57.81%), Query Frame = 3
Query: 762 GESEIHQLKLIINLCGSINEESWPGVSKLEAFKRLERT-NHKRFVRQQLLKVIDCHSAVXXXXXXXXXXXXXXXTADIALMHEFFYEDPPAGDLSDF--SNAGSFYEFLS---------NQKKPNQSK 1109
G +E HQL LI LCGSI E WP V K E F++LE KR V+ +L + A+DLIDKLL+LDP +R+ +D AL H+FF+ DP DL ++ S +E+L+ Q+ NQS+
Sbjct: 231 GNTEQHQLALISQLCGSITPEVWPNVDKYELFEKLELVKGQKRKVKDRLKAYVRDPYALDLIDKLLVLDPAQRIDSDDALNHDFFWSDPMPSDLKGMLSTHLTSMFEYLAPPRRKGSQITQQSTNQSR 358
BLAST of Cyclin-dependent kinase 9 vs. Ensembl Mouse
Match: Cdk9 (cyclin-dependent kinase 9 (CDC2-related kinase) [Source:MGI Symbol;Acc:MGI:1328368]) HSP 1 Score: 224.172 bits (570), Expect = 5.200e-71 Identity = 103/179 (57.54%), Postives = 133/179 (74.30%), Query Frame = 1
Query: 226 LEQEKEGFPITALREIKILQSLNHPNIVCLREICCSSPTKEKLYKPEFYLLFDLCDHDLAGLLSDQNMKFSLPQRKSIMKQLFTGIFYLHRNNVIHRDLKAANILIEKHGTLKIADFGLARYTIKSPKPDHPPKYTSRVVTMWYRPPEILLNDRHYDKSVDMWGAGCIMAELWTKYPIM 762
+E EKEGFPITALREIKILQ L H N+V L EIC + + K YL+FD C+HDLAGLLS+ +KF+L + K +M+ L G++Y+HRN ++HRD+KAAN+LI + G LK+ADFGLAR K P +YT+RVVT+WYRPPE+LL +R Y +D+WGAGCIMAE+WT+ PIM
Sbjct: 1 MENEKEGFPITALREIKILQLLKHENVVNLIEICRTKASPYNRCKGSIYLVFDFCEHDLAGLLSNVLVKFTLSEIKRVMQMLLNGLYYIHRNKILHRDMKAANVLITRDGVLKLADFGLAR-AFSLAKNSQPNRYTNRVVTLWYRPPELLLGERDYGPPIDLWGAGCIMAEMWTRSPIM 178 HSP 2 Score: 63.929 bits (154), Expect = 5.200e-71 Identity = 54/128 (42.19%), Postives = 74/128 (57.81%), Query Frame = 3
Query: 762 GESEIHQLKLIINLCGSINEESWPGVSKLEAFKRLERT-NHKRFVRQQLLKVIDCHSAVXXXXXXXXXXXXXXXTADIALMHEFFYEDPPAGDLSDF--SNAGSFYEFLS---------NQKKPNQSK 1109
G +E HQL LI LCGSI E WP V K E F++LE KR V+ +L + A+DLIDKLL+LDP +R+ +D AL H+FF+ DP DL ++ S +E+L+ Q+ NQS+
Sbjct: 180 GNTEQHQLALISQLCGSITPEVWPNVDKYELFEKLELVKGQKRKVKDRLKAYVRDPYALDLIDKLLVLDPAQRIDSDDALNHDFFWSDPMPSDLKGMLSTHLTSMFEYLAPPRRKGSQITQQSTNQSR 307
BLAST of Cyclin-dependent kinase 9 vs. Ensembl Mouse
Match: Cdk13 (cyclin-dependent kinase 13 [Source:MGI Symbol;Acc:MGI:1916812]) HSP 1 Score: 206.838 bits (525), Expect = 1.081e-58 Identity = 103/220 (46.82%), Postives = 149/220 (67.73%), Query Frame = 1
Query: 118 VDQYEKLQKIGQGTFGEVFKVRDIQTKKYYALKRIKLEQEKEGFPITALREIKILQSLNHPNIVCLREICCSSPTKE-----KLYKPEFYLLFDLCDHDLAGLLSDQNMKFSLPQRKSIMKQLFTGIFYLHRNNVIHRDLKAANILIEKHGTLKIADFGLAR-YTIKSPKPDHPPKYTSRVVTMWYRPPEILLNDRHYDKSVDMWGAGCIMAELWTKYPI 759
VD+++ + IG+GT+G+V+K RD T + ALK+++L+ EKEGFPITA+REIKIL+ L H +I+ ++EI KE K K FYL+F+ DHDL GLL + F+ KS M+QL G+ Y H+ N +HRD+K +NIL+ G +K+ADFGLAR Y+ + +P YT++V+T+WYRPPE+LL + Y ++D+W GCI+ EL+TK PI
Sbjct: 88 VDKFDIIGIIGEGTYGQVYKARDKDTGEMVALKKVRLDNEKEGFPITAIREIKILRQLTHQSIINMKEIVTD---KEDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFNENHIKSFMRQLMEGLDYCHKKNFLHRDIKCSNILLNNRGQIKLADFGLARLYSSEESRP-----YTNKVITLWYRPPELLLGEERYTPAIDVWSCGCILGELFTKKPI 299
BLAST of Cyclin-dependent kinase 9 vs. Ensembl Mouse
Match: Cdk13 (cyclin-dependent kinase 13 [Source:MGI Symbol;Acc:MGI:1916812]) HSP 1 Score: 207.994 bits (528), Expect = 1.853e-58 Identity = 103/220 (46.82%), Postives = 149/220 (67.73%), Query Frame = 1
Query: 118 VDQYEKLQKIGQGTFGEVFKVRDIQTKKYYALKRIKLEQEKEGFPITALREIKILQSLNHPNIVCLREICCSSPTKE-----KLYKPEFYLLFDLCDHDLAGLLSDQNMKFSLPQRKSIMKQLFTGIFYLHRNNVIHRDLKAANILIEKHGTLKIADFGLAR-YTIKSPKPDHPPKYTSRVVTMWYRPPEILLNDRHYDKSVDMWGAGCIMAELWTKYPI 759
VD+++ + IG+GT+G+V+K RD T + ALK+++L+ EKEGFPITA+REIKIL+ L H +I+ ++EI KE K K FYL+F+ DHDL GLL + F+ KS M+QL G+ Y H+ N +HRD+K +NIL+ G +K+ADFGLAR Y+ + +P YT++V+T+WYRPPE+LL + Y ++D+W GCI+ EL+TK PI
Sbjct: 702 VDKFDIIGIIGEGTYGQVYKARDKDTGEMVALKKVRLDNEKEGFPITAIREIKILRQLTHQSIINMKEIVTD---KEDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFNENHIKSFMRQLMEGLDYCHKKNFLHRDIKCSNILLNNRGQIKLADFGLARLYSSEESRP-----YTNKVITLWYRPPELLLGEERYTPAIDVWSCGCILGELFTKKPI 913
BLAST of Cyclin-dependent kinase 9 vs. Ensembl Mouse
Match: Cdk13 (cyclin-dependent kinase 13 [Source:MGI Symbol;Acc:MGI:1916812]) HSP 1 Score: 207.608 bits (527), Expect = 3.002e-58 Identity = 103/220 (46.82%), Postives = 149/220 (67.73%), Query Frame = 1
Query: 118 VDQYEKLQKIGQGTFGEVFKVRDIQTKKYYALKRIKLEQEKEGFPITALREIKILQSLNHPNIVCLREICCSSPTKE-----KLYKPEFYLLFDLCDHDLAGLLSDQNMKFSLPQRKSIMKQLFTGIFYLHRNNVIHRDLKAANILIEKHGTLKIADFGLAR-YTIKSPKPDHPPKYTSRVVTMWYRPPEILLNDRHYDKSVDMWGAGCIMAELWTKYPI 759
VD+++ + IG+GT+G+V+K RD T + ALK+++L+ EKEGFPITA+REIKIL+ L H +I+ ++EI KE K K FYL+F+ DHDL GLL + F+ KS M+QL G+ Y H+ N +HRD+K +NIL+ G +K+ADFGLAR Y+ + +P YT++V+T+WYRPPE+LL + Y ++D+W GCI+ EL+TK PI
Sbjct: 702 VDKFDIIGIIGEGTYGQVYKARDKDTGEMVALKKVRLDNEKEGFPITAIREIKILRQLTHQSIINMKEIVTD---KEDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFNENHIKSFMRQLMEGLDYCHKKNFLHRDIKCSNILLNNRGQIKLADFGLARLYSSEESRP-----YTNKVITLWYRPPELLLGEERYTPAIDVWSCGCILGELFTKKPI 913
BLAST of Cyclin-dependent kinase 9 vs. UniProt/SwissProt
Match: sp|Q5ZKN1|CDK9_CHICK (Cyclin-dependent kinase 9 OS=Gallus gallus OX=9031 GN=CDK9 PE=2 SV=1) HSP 1 Score: 267.314 bits (682), Expect = 8.711e-85 Identity = 125/215 (58.14%), Postives = 160/215 (74.42%), Query Frame = 1
Query: 118 VDQYEKLQKIGQGTFGEVFKVRDIQTKKYYALKRIKLEQEKEGFPITALREIKILQSLNHPNIVCLREICCSSPTKEKLYKPEFYLLFDLCDHDLAGLLSDQNMKFSLPQRKSIMKQLFTGIFYLHRNNVIHRDLKAANILIEKHGTLKIADFGLARYTIKSPKPDHPPKYTSRVVTMWYRPPEILLNDRHYDKSVDMWGAGCIMAELWTKYPIM 762
V +YEKL KIGQGTFGEVFK + QT K ALK++ +E EKEGFPITALREIKILQ L H N+V L EIC + + K YL+FD C+HDLAGLLS+ ++KF+L + K +M+ L G++Y+HRN ++HRD+KAAN+LI + G LK+ADFGLAR K P +YT+RVVT+WYRPPE+LL +R Y +D+WG GCIMAE+WT+ PIM
Sbjct: 16 VSKYEKLAKIGQGTFGEVFKAKHRQTGKKVALKKVLMENEKEGFPITALREIKILQLLKHENVVNLIEICRTKASPYNRCKGSIYLVFDFCEHDLAGLLSNTHVKFTLSEIKKVMQMLLNGLYYIHRNKILHRDMKAANVLITRDGVLKLADFGLAR-AFSLAKNSQPNRYTNRVVTLWYRPPELLLGERDYGPPIDLWGGGCIMAEMWTRSPIM 229 HSP 2 Score: 65.0846 bits (157), Expect = 3.511e-10 Identity = 56/144 (38.89%), Postives = 81/144 (56.25%), Query Frame = 3
Query: 762 GESEIHQLKLIINLCGSINEESWPGVSKLEAFKRLE-RTNHKRFVRQQLLKVIDCHSAVXXXXXXXXXXXXXXXTADIALMHEFFYEDPPAGDLSDF--SNAGSFYEFLSNQKK-----PNQSKANYLNRDAMKETSGILDRIY 1169
G +E HQL LI LCGSI E WP V K E +++LE KR V+ +L + A+DLIDKLL+LDP +R+ +D AL H+FF+ DP DL + ++ S +E+L+ ++ P Q N A +T DR++
Sbjct: 231 GNTEQHQLTLISQLCGSITPEVWPNVDKYELYQKLELPKGQKRKVKDRLKAYVKDPYALDLIDKLLVLDPAQRIDSDDALNHDFFWSDPMPSDLKNMLSTHNQSMFEYLAPPRRRGGHMPQQPANQGRNPAATNQTE--FDRVF 372
BLAST of Cyclin-dependent kinase 9 vs. UniProt/SwissProt
Match: sp|P50750|CDK9_HUMAN (Cyclin-dependent kinase 9 OS=Homo sapiens OX=9606 GN=CDK9 PE=1 SV=3) HSP 1 Score: 266.159 bits (679), Expect = 1.934e-84 Identity = 125/216 (57.87%), Postives = 160/216 (74.07%), Query Frame = 1
Query: 115 HVDQYEKLQKIGQGTFGEVFKVRDIQTKKYYALKRIKLEQEKEGFPITALREIKILQSLNHPNIVCLREICCSSPTKEKLYKPEFYLLFDLCDHDLAGLLSDQNMKFSLPQRKSIMKQLFTGIFYLHRNNVIHRDLKAANILIEKHGTLKIADFGLARYTIKSPKPDHPPKYTSRVVTMWYRPPEILLNDRHYDKSVDMWGAGCIMAELWTKYPIM 762
V +YEKL KIGQGTFGEVFK R +T + ALK++ +E EKEGFPITALREIKILQ L H N+V L EIC + + K YL+FD C+HDLAGLLS+ +KF+L + K +M+ L G++Y+HRN ++HRD+KAAN+LI + G LK+ADFGLAR K P +YT+RVVT+WYRPPE+LL +R Y +D+WGAGCIMAE+WT+ PIM
Sbjct: 15 EVSKYEKLAKIGQGTFGEVFKARHRKTGQKVALKKVLMENEKEGFPITALREIKILQLLKHENVVNLIEICRTKASPYNRCKGSIYLVFDFCEHDLAGLLSNVLVKFTLSEIKRVMQMLLNGLYYIHRNKILHRDMKAANVLITRDGVLKLADFGLAR-AFSLAKNSQPNRYTNRVVTLWYRPPELLLGERDYGPPIDLWGAGCIMAEMWTRSPIM 229 HSP 2 Score: 60.8474 bits (146), Expect = 7.563e-9 Identity = 52/128 (40.62%), Postives = 73/128 (57.03%), Query Frame = 3
Query: 762 GESEIHQLKLIINLCGSINEESWPGVSKLEAFKRLERT-NHKRFVRQQLLKVIDCHSAVXXXXXXXXXXXXXXXTADIALMHEFFYEDPPAGDLSDF--SNAGSFYEFLS---------NQKKPNQSK 1109
G +E HQL LI LCGSI E WP V E +++LE KR V+ +L + A+DLIDKLL+LDP +R+ +D AL H+FF+ DP DL ++ S +E+L+ Q+ NQS+
Sbjct: 231 GNTEQHQLALISQLCGSITPEVWPNVDNYELYEKLELVKGQKRKVKDRLKAYVRDPYALDLIDKLLVLDPAQRIDSDDALNHDFFWSDPMPSDLKGMLSTHLTSMFEYLAPPRRKGSQITQQSTNQSR 358
BLAST of Cyclin-dependent kinase 9 vs. UniProt/SwissProt
Match: sp|Q641Z4|CDK9_RAT (Cyclin-dependent kinase 9 OS=Rattus norvegicus OX=10116 GN=Cdk9 PE=2 SV=1) HSP 1 Score: 266.159 bits (679), Expect = 2.085e-84 Identity = 125/216 (57.87%), Postives = 160/216 (74.07%), Query Frame = 1
Query: 115 HVDQYEKLQKIGQGTFGEVFKVRDIQTKKYYALKRIKLEQEKEGFPITALREIKILQSLNHPNIVCLREICCSSPTKEKLYKPEFYLLFDLCDHDLAGLLSDQNMKFSLPQRKSIMKQLFTGIFYLHRNNVIHRDLKAANILIEKHGTLKIADFGLARYTIKSPKPDHPPKYTSRVVTMWYRPPEILLNDRHYDKSVDMWGAGCIMAELWTKYPIM 762
V +YEKL KIGQGTFGEVFK + QT + ALK++ +E EKEGFPITALREIKILQ L H N+V L EIC + + K YL+FD C+HDLAGLLS+ +KF+L + K +M+ L G++Y+HRN ++HRD+KAAN+LI + G LK+ADFGLAR K P +YT+RVVT+WYRPPE+LL +R Y +D+WGAGCIMAE+WT+ PIM
Sbjct: 15 EVTKYEKLAKIGQGTFGEVFKAKHRQTGQKVALKKVLMENEKEGFPITALREIKILQLLKHENVVNLIEICRTKASPYNRCKGSIYLVFDFCEHDLAGLLSNVLVKFTLSEIKRVMQMLLNGLYYIHRNKILHRDMKAANVLITRDGVLKLADFGLAR-AFSLAKNSQPNRYTNRVVTLWYRPPELLLGERDYGPPIDLWGAGCIMAEMWTRSPIM 229 HSP 2 Score: 63.929 bits (154), Expect = 7.817e-10 Identity = 54/128 (42.19%), Postives = 74/128 (57.81%), Query Frame = 3
Query: 762 GESEIHQLKLIINLCGSINEESWPGVSKLEAFKRLERT-NHKRFVRQQLLKVIDCHSAVXXXXXXXXXXXXXXXTADIALMHEFFYEDPPAGDLSDF--SNAGSFYEFLS---------NQKKPNQSK 1109
G +E HQL LI LCGSI E WP V K E F++LE KR V+ +L + A+DLIDKLL+LDP +R+ +D AL H+FF+ DP DL ++ S +E+L+ Q+ NQS+
Sbjct: 231 GNTEQHQLALISQLCGSITPEVWPNVDKYELFEKLELVKGQKRKVKDRLKAYVRDPYALDLIDKLLVLDPAQRIDSDDALNHDFFWSDPMPSDLKGMLSTHLTSMFEYLAPPRRKGSQITQQSTNQSR 358
BLAST of Cyclin-dependent kinase 9 vs. UniProt/SwissProt
Match: sp|Q99J95|CDK9_MOUSE (Cyclin-dependent kinase 9 OS=Mus musculus OX=10090 GN=Cdk9 PE=1 SV=1) HSP 1 Score: 266.159 bits (679), Expect = 2.085e-84 Identity = 125/216 (57.87%), Postives = 160/216 (74.07%), Query Frame = 1
Query: 115 HVDQYEKLQKIGQGTFGEVFKVRDIQTKKYYALKRIKLEQEKEGFPITALREIKILQSLNHPNIVCLREICCSSPTKEKLYKPEFYLLFDLCDHDLAGLLSDQNMKFSLPQRKSIMKQLFTGIFYLHRNNVIHRDLKAANILIEKHGTLKIADFGLARYTIKSPKPDHPPKYTSRVVTMWYRPPEILLNDRHYDKSVDMWGAGCIMAELWTKYPIM 762
V +YEKL KIGQGTFGEVFK + QT + ALK++ +E EKEGFPITALREIKILQ L H N+V L EIC + + K YL+FD C+HDLAGLLS+ +KF+L + K +M+ L G++Y+HRN ++HRD+KAAN+LI + G LK+ADFGLAR K P +YT+RVVT+WYRPPE+LL +R Y +D+WGAGCIMAE+WT+ PIM
Sbjct: 15 EVTKYEKLAKIGQGTFGEVFKAKHRQTGQKVALKKVLMENEKEGFPITALREIKILQLLKHENVVNLIEICRTKASPYNRCKGSIYLVFDFCEHDLAGLLSNVLVKFTLSEIKRVMQMLLNGLYYIHRNKILHRDMKAANVLITRDGVLKLADFGLAR-AFSLAKNSQPNRYTNRVVTLWYRPPELLLGERDYGPPIDLWGAGCIMAEMWTRSPIM 229 HSP 2 Score: 63.929 bits (154), Expect = 7.817e-10 Identity = 54/128 (42.19%), Postives = 74/128 (57.81%), Query Frame = 3
Query: 762 GESEIHQLKLIINLCGSINEESWPGVSKLEAFKRLERT-NHKRFVRQQLLKVIDCHSAVXXXXXXXXXXXXXXXTADIALMHEFFYEDPPAGDLSDF--SNAGSFYEFLS---------NQKKPNQSK 1109
G +E HQL LI LCGSI E WP V K E F++LE KR V+ +L + A+DLIDKLL+LDP +R+ +D AL H+FF+ DP DL ++ S +E+L+ Q+ NQS+
Sbjct: 231 GNTEQHQLALISQLCGSITPEVWPNVDKYELFEKLELVKGQKRKVKDRLKAYVRDPYALDLIDKLLVLDPAQRIDSDDALNHDFFWSDPMPSDLKGMLSTHLTSMFEYLAPPRRKGSQITQQSTNQSR 358
BLAST of Cyclin-dependent kinase 9 vs. UniProt/SwissProt
Match: sp|Q6GLD8|CDK9_XENTR (Cyclin-dependent kinase 9 OS=Xenopus tropicalis OX=8364 GN=cdk9 PE=2 SV=1) HSP 1 Score: 266.159 bits (679), Expect = 2.456e-84 Identity = 128/219 (58.45%), Postives = 164/219 (74.89%), Query Frame = 1
Query: 118 VDQYEKLQKIGQGTFGEVFKVRDIQTKKYYALKRIKLEQEKEGFPITALREIKILQSLNHPNIVCLREICCS--SPTKEKLY--KPEFYLLFDLCDHDLAGLLSDQNMKFSLPQRKSIMKQLFTGIFYLHRNNVIHRDLKAANILIEKHGTLKIADFGLARYTIKSPKPDHPPKYTSRVVTMWYRPPEILLNDRHYDKSVDMWGAGCIMAELWTKYPIM 762
V +YE+L KIGQGTFGEVFK + QT K ALK++ +E EKEGFPITALREIKILQ L H N+V L EIC + SPT + K +L+FD C+HDLAGLLS+ ++KF+L + K +M+ L G++Y+HRN ++HRD+KAAN+LI + G LK+ADFGLAR K P KYT+RVVT+WYRPPE+LL +R Y +D+WGAGCIMAE+WT+ PIM
Sbjct: 16 VSKYERLAKIGQGTFGEVFKAKHRQTGKKVALKKVLMENEKEGFPITALREIKILQLLKHENVVNLIEICRTKISPTANQYNRCKGTIFLVFDFCEHDLAGLLSNAHVKFTLSEIKKVMQMLLNGLYYIHRNKILHRDMKAANVLITRDGVLKLADFGLAR-AFSLAKNSQPNKYTNRVVTLWYRPPELLLGERDYGPPIDLWGAGCIMAEMWTRSPIM 233 HSP 2 Score: 64.3142 bits (155), Expect = 6.073e-10 Identity = 55/144 (38.19%), Postives = 82/144 (56.94%), Query Frame = 3
Query: 762 GESEIHQLKLIINLCGSINEESWPGVSKLEAFKRLE-RTNHKRFVRQQLLKVIDCHSAVXXXXXXXXXXXXXXXTADIALMHEFFYEDPPAGDLSDF--SNAGSFYEFLSNQKK-----PNQSKANYLNRDAMKETSGILDRIY 1169
G +E HQL LI LCGSI E WP V K E +++LE KR V+++L + A+DLIDKLL+LDP +R+ +D AL H+FF+ DP DL + ++ S +E+L+ ++ P Q N A ++ DR++
Sbjct: 235 GNTEQHQLTLISQLCGSITPEVWPNVDKYELYQKLELPKGQKRKVKERLKAYVKDLYALDLIDKLLVLDPAQRIDSDDALNHDFFWSDPMPSDLKNMLSTHNQSMFEYLAPPRRRGGHMPQQPANQARNPAATNQSE--FDRVF 376
BLAST of Cyclin-dependent kinase 9 vs. TrEMBL
Match: A0A5J4N659 (Cyclin-dependent kinase 9 OS=Paragonimus westermani OX=34504 GN=DEA37_0012232 PE=3 SV=1) HSP 1 Score: 349.747 bits (896), Expect = 5.171e-116 Identity = 164/245 (66.94%), Postives = 203/245 (82.86%), Query Frame = 1
Query: 31 SEVINDISFGLQDFFKRIQSDPN-LSVLKHVDQYEKLQKIGQGTFGEVFKVRDIQTKKYYALKRIKLEQEKEGFPITALREIKILQSLNHPNIVCLREICCSSPTKEKLYKPEFYLLFDLCDHDLAGLLSDQNMKFSLPQRKSIMKQLFTGIFYLHRNNVIHRDLKAANILIEKHGTLKIADFGLARYTIKSPKPDHPPKYTSRVVTMWYRPPEILLNDRHYDKSVDMWGAGCIMAELWTKYPIM 762
SE+++D+ +FF +++ + L+ K VDQY KLQKIGQGTFGEVFKVR TK+++ALKRI++EQEKEGFPITALREI+ILQSLNH NIVCL+EIC S+P ++P+F+L+F+ CDHDLAGL Q + F+ P +K+IMKQL TG++YLH NNV+HRDLKAANILI+K+G LKIADFGLAR T+ S +PD P +YT+RVVT+WYRPPEILLNDRHY K VD+WGAGCIMAELWTKYPIM
Sbjct: 9 SELLSDLQADCTNFFSTVETRIDALAQTKSVDQYVKLQKIGQGTFGEVFKVRHKSTKQHFALKRIRMEQEKEGFPITALREIRILQSLNHENIVCLKEICHSAPNARNGFRPQFFLVFEFCDHDLAGL--SQQVDFTDPVKKAIMKQLLTGLYYLHLNNVLHRDLKAANILIDKNGVLKIADFGLARTTVASIRPDRPTRYTTRVVTLWYRPPEILLNDRHYGKPVDLWGAGCIMAELWTKYPIM 251
BLAST of Cyclin-dependent kinase 9 vs. TrEMBL
Match: A0A183QY46 (Protein kinase domain-containing protein OS=Schistosoma rodhaini OX=6188 PE=3 SV=1) HSP 1 Score: 350.517 bits (898), Expect = 1.487e-114 Identity = 167/245 (68.16%), Postives = 199/245 (81.22%), Query Frame = 1
Query: 31 SEVINDISFGLQDFFKRIQSD-PNLSVLKHVDQYEKLQKIGQGTFGEVFKVRDIQTKKYYALKRIKLEQEKEGFPITALREIKILQSLNHPNIVCLREICCSSPTKEKLYKPEFYLLFDLCDHDLAGLLSDQNMKFSLPQRKSIMKQLFTGIFYLHRNNVIHRDLKAANILIEKHGTLKIADFGLARYTIKSPKPDHPPKYTSRVVTMWYRPPEILLNDRHYDKSVDMWGAGCIMAELWTKYPIM 762
+E+++D+ FF + + +S K VDQY +LQKIGQGTFGEVFKVR TK+++ALKRI++EQEKEGFPITALREI+ILQSLNH NIVCL+EIC S P +KP+FYL+F+ CDHDLAGL Q + F+ P +K+IMKQLFTG+FYLH NNV+HRDLKAANILI+K+G LKIADFGLAR T+ S +PD P +YT RVVT+WYRPPEILLNDRHY K VDMWGAGCIMAELWTKYPIM
Sbjct: 11 AELLSDLQADYTKFFSMAERELEGISKTKPVDQYVRLQKIGQGTFGEVFKVRHKSTKQHFALKRIRMEQEKEGFPITALREIRILQSLNHENIVCLKEICHSPPNAGNGFKPQFYLVFEFCDHDLAGL--SQQIDFTEPVKKAIMKQLFTGVFYLHLNNVLHRDLKAANILIDKNGILKIADFGLARTTVASIRPDRPTRYTGRVVTLWYRPPEILLNDRHYGKPVDMWGAGCIMAELWTKYPIM 253 HSP 2 Score: 78.5666 bits (192), Expect = 3.944e-12 Identity = 48/109 (44.04%), Postives = 61/109 (55.96%), Query Frame = 3
Query: 762 GESEIHQLKLIINLCGSINEESWPGVSKLEAFKRLERTNHKRFVRQQLLKVIDCHSAVXXXXXXXXXXXXXXXTADIALMHEFFYEDPPAGDLSDFSNAG-SFYEFLSN 1085
G++EI QL LIINLCGSI E WPGV +LE F+ + QLL V+D + A+ AL H++FYEDPP GDL FS +G S+ EFLS+
Sbjct: 255 GDNEISQLNLIINLCGSITPEIWPGVERLETFREAHLID-------QLL-VLDPSKRL---------------DAEQALSHDYFYEDPPVGDLRSFSKSGTSYLEFLSS 340
BLAST of Cyclin-dependent kinase 9 vs. TrEMBL
Match: A0A4S2M669 (Protein kinase domain-containing protein OS=Opisthorchis felineus OX=147828 GN=CRM22_003678 PE=3 SV=1) HSP 1 Score: 345.51 bits (885), Expect = 1.731e-114 Identity = 163/245 (66.53%), Postives = 202/245 (82.45%), Query Frame = 1
Query: 31 SEVINDISFGLQDFFKRIQSD-PNLSVLKHVDQYEKLQKIGQGTFGEVFKVRDIQTKKYYALKRIKLEQEKEGFPITALREIKILQSLNHPNIVCLREICCSSPTKEKLYKPEFYLLFDLCDHDLAGLLSDQNMKFSLPQRKSIMKQLFTGIFYLHRNNVIHRDLKAANILIEKHGTLKIADFGLARYTIKSPKPDHPPKYTSRVVTMWYRPPEILLNDRHYDKSVDMWGAGCIMAELWTKYPIM 762
SE++ D+ FF ++++ +L+ K VDQY KLQKIGQGTFGEVFKVR TK+++ALKRI++EQEKEGFPITALREI+ILQ+LNH NIVCL+EIC ++P YKP+F+L+F+ CDHDLAGL Q + F+ P +K+IMKQL TG++YLH NN++HRDLKAANILI+K+G LKIADFGLAR T+ S +PD P +YT+RVVT+WYRPPEILLNDRHY K VD+WGAGCIMAELWTKYPIM
Sbjct: 9 SELLADLQADNTKFFCLVENNIESLAKTKSVDQYVKLQKIGQGTFGEVFKVRHKSTKQHFALKRIRMEQEKEGFPITALREIRILQALNHENIVCLKEICHTAPNARNGYKPQFFLVFEFCDHDLAGL--SQQVDFTDPVKKAIMKQLLTGLYYLHLNNILHRDLKAANILIDKNGILKIADFGLARTTVASIRPDRPTRYTTRVVTLWYRPPEILLNDRHYGKPVDLWGAGCIMAELWTKYPIM 251 HSP 2 Score: 98.2117 bits (243), Expect = 1.731e-114 Identity = 68/133 (51.13%), Postives = 89/133 (66.92%), Query Frame = 3
Query: 762 GESEIHQLKLIINLCGSINEESWPGVSKLEAFK--RLERTNHKRFVRQQLLKVIDCHSAVXXXXXXXXXXXXXXXTADIALMHEFFYEDPPAGDLSDFSNAG-SFYEFLSNQKKPNQSKANYLNRDAMKETSG 1151
G++E++QL LIINLCGSI E WPGV +LE+F+ RL + + KR VR++L I +AVDLID+LL+LDP KRL A+ AL H++FYEDPP GDL FS +G S+ EFLS+ P +NR G
Sbjct: 253 GDNELNQLNLIINLCGSITPEVWPGVQRLESFREARLPQ-DIKRHVREKLTPKITSLAAVDLIDQLLVLDPSKRLDAEQALSHDYFYEDPPPGDLRSFSKSGTSYLEFLSSSNNPRGRAPPAMNRAGGPRGPG 384
BLAST of Cyclin-dependent kinase 9 vs. TrEMBL
Match: A0A3R7GNE5 (Cyclin-dependent kinase 9 OS=Clonorchis sinensis OX=79923 GN=cdk9 PE=3 SV=1) HSP 1 Score: 345.51 bits (885), Expect = 1.961e-114 Identity = 163/245 (66.53%), Postives = 202/245 (82.45%), Query Frame = 1
Query: 31 SEVINDISFGLQDFFKRIQSD-PNLSVLKHVDQYEKLQKIGQGTFGEVFKVRDIQTKKYYALKRIKLEQEKEGFPITALREIKILQSLNHPNIVCLREICCSSPTKEKLYKPEFYLLFDLCDHDLAGLLSDQNMKFSLPQRKSIMKQLFTGIFYLHRNNVIHRDLKAANILIEKHGTLKIADFGLARYTIKSPKPDHPPKYTSRVVTMWYRPPEILLNDRHYDKSVDMWGAGCIMAELWTKYPIM 762
SE++ D+ FF ++++ +L+ K VDQY KLQKIGQGTFGEVFKVR TK+++ALKRI++EQEKEGFPITALREI+ILQ+LNH NIVCL+EIC ++P YKP+F+L+F+ CDHDLAGL Q + F+ P +K+IMKQL TG++YLH NN++HRDLKAANILI+K+G LKIADFGLAR T+ S +PD P +YT+RVVT+WYRPPEILLNDRHY K VD+WGAGCIMAELWTKYPIM
Sbjct: 9 SELLADLQADNTKFFCLVENNIESLAKTKSVDQYVKLQKIGQGTFGEVFKVRHKSTKQHFALKRIRMEQEKEGFPITALREIRILQALNHENIVCLKEICHTAPNARNGYKPQFFLVFEFCDHDLAGL--SQQVDFTDPVKKAIMKQLLTGLYYLHLNNILHRDLKAANILIDKNGILKIADFGLARTTVASIRPDRPTRYTTRVVTLWYRPPEILLNDRHYGKPVDLWGAGCIMAELWTKYPIM 251 HSP 2 Score: 98.2117 bits (243), Expect = 1.961e-114 Identity = 68/133 (51.13%), Postives = 89/133 (66.92%), Query Frame = 3
Query: 762 GESEIHQLKLIINLCGSINEESWPGVSKLEAFK--RLERTNHKRFVRQQLLKVIDCHSAVXXXXXXXXXXXXXXXTADIALMHEFFYEDPPAGDLSDFSNAG-SFYEFLSNQKKPNQSKANYLNRDAMKETSG 1151
G++E++QL LIINLCGSI E WPGV +LE+F+ RL + + KR VR++L I +AVDLID+LL+LDP KRL A+ AL H++FYEDPP GDL FS +G S+ EFLS+ P +NR G
Sbjct: 253 GDNELNQLNLIINLCGSITPEVWPGVQRLESFREARLPQ-DIKRHVREKLTPKITSLAAVDLIDQLLVLDPSKRLDAEQALSHDYFYEDPPPGDLRSFSKSGTSYLEFLSSSNNPRGRAPPAMNRAGGPRGPG 384
BLAST of Cyclin-dependent kinase 9 vs. TrEMBL
Match: A0A504YXD6 (Cell division protein kinase 9-B OS=Fasciola gigantica OX=46835 GN=FGIG_10308 PE=3 SV=1) HSP 1 Score: 345.51 bits (885), Expect = 2.474e-114 Identity = 165/251 (65.74%), Postives = 200/251 (79.68%), Query Frame = 1
Query: 34 EVINDISFGLQDFFKRIQSD-PNLSVLKHVDQYEKLQKIGQGTFGEVFKVRDIQTKKYYALKRIKLEQEKEGFPITALREIKILQSLNHPNIVCLREICCSSPTKEKLYKPEFYLLFDLCDHDLAGLLSDQNMKFSLPQRKSIMKQLFTGIFYLHRNNVIHRDLKAANILIEKHGTLKIADFGLARYTIKSPKPDHPPKYTSRVVTMWYRPPEILLNDRHYDKSVDMWGAGCIMAELWTKYPIMGRVKYIN 783
E+ D+ FF I++ LS K V+QY +LQKIGQGTFGEVFKVR TK+++ALKRI++EQEKEGFPITALREI+ILQSLNH NIVCL+EIC S+P +KP+F+L+F+ CDHDLAGL Q + F+ P +K+IMKQL TG++YLH NNV+HRDLKAANILI+K+G LKIADFGLAR T+ S +PD P +YT RVVT+WYRPPEILLNDRHY K+VD+WGAGCIMAELWTK+PIM IN
Sbjct: 29 ELFGDLQADCTKFFTMIENRIDTLSQTKSVEQYARLQKIGQGTFGEVFKVRHKSTKQHFALKRIRMEQEKEGFPITALREIRILQSLNHENIVCLKEICHSAPNARNGFKPQFFLVFEFCDHDLAGL--SQQVDFTEPVKKAIMKQLLTGLYYLHLNNVLHRDLKAANILIDKNGVLKIADFGLARTTVASLRPDRPTRYTGRVVTLWYRPPEILLNDRHYGKAVDLWGAGCIMAELWTKFPIMQGDTEIN 277 HSP 2 Score: 97.8265 bits (242), Expect = 2.474e-114 Identity = 67/125 (53.60%), Postives = 88/125 (70.40%), Query Frame = 3
Query: 762 GESEIHQLKLIINLCGSINEESWPGVSKLEAFK--RLERTNHKRFVRQQLLKVIDCHSAVXXXXXXXXXXXXXXXTADIALMHEFFYEDPPAGDLSDFSNAG-SFYEFLSNQKKPNQSKANYLNR 1127
G++EI+QL LIINLCGSI E WPGV +LEA++ RL + + KR VR++L I +AV+LID+LL+LDP KRL A+ AL H++FYEDPP GDL FS +G S+ EFLS+ P +NR
Sbjct: 272 GDTEINQLNLIINLCGSITPEVWPGVQRLEAYREARLPQ-DIKRHVREKLTPKIPSLAAVELIDQLLVLDPSKRLDAEQALSHDYFYEDPPPGDLRTFSKSGTSYLEFLSSSNNPRGRIQPGINR 395
BLAST of Cyclin-dependent kinase 9 vs. Ensembl Cavefish
Match: cdk9 (cyclin-dependent kinase 9 (CDC2-related kinase) [Source:ZFIN;Acc:ZDB-GENE-030131-321]) HSP 1 Score: 271.166 bits (692), Expect = 3.280e-86 Identity = 126/213 (59.15%), Postives = 160/213 (75.12%), Query Frame = 1
Query: 124 QYEKLQKIGQGTFGEVFKVRDIQTKKYYALKRIKLEQEKEGFPITALREIKILQSLNHPNIVCLREICCSSPTKEKLYKPEFYLLFDLCDHDLAGLLSDQNMKFSLPQRKSIMKQLFTGIFYLHRNNVIHRDLKAANILIEKHGTLKIADFGLARYTIKSPKPDHPPKYTSRVVTMWYRPPEILLNDRHYDKSVDMWGAGCIMAELWTKYPIM 762
+YEKL KIGQGTFGEVFK + QT K ALK++ +E EKEGFPITALREIKILQ L H N+V L EIC + T+ YK YL+FD C+HDLAGLLS+ N+KF+L + K +M+ L G++Y+HRN ++HRD+KAAN+LI + G LK+ADFGLAR K +YT+RVVT+WYRPPE+LL +R Y +D+WG GCIMAE+WT+ PIM
Sbjct: 103 KYEKLAKIGQGTFGEVFKAKHRQTGKKVALKKVLMENEKEGFPITALREIKILQLLKHENVVNLIEICRTKATQFNRYKGSIYLVFDFCEHDLAGLLSNANVKFTLAEIKKVMQMLLNGLYYIHRNKILHRDMKAANVLITRDGILKLADFGLAR-AFSLAKNSQGNRYTNRVVTLWYRPPELLLGERDYGPPIDLWGGGCIMAEMWTRSPIM 314 HSP 2 Score: 63.929 bits (154), Expect = 1.298e-10 Identity = 56/143 (39.16%), Postives = 83/143 (58.04%), Query Frame = 3
Query: 762 GESEIHQLKLIINLCGSINEESWPGV-SKLEAFKRLE-RTNHKRFVRQQLLKVIDCHSAVXXXXXXXXXXXXXXXTADIALMHEFFYEDPPAGDLSDF--SNAGSFYEFLSNQKKPN---QSKANYLNRDAMKETSGILDRIY 1169
G +E HQL LI LCGSI E WPGV K E ++++E KR V+ +L + A+DLIDKLL+LDP +R+ +D AL H+FF+ DP DL + ++ S +E+L+ ++ Q AN NR+ + DR++
Sbjct: 316 GNTEQHQLTLISQLCGSITAEVWPGVDKKYELYQKMELPKGQKRKVKDRLKAYVKDPYALDLIDKLLVLDPAQRIDSDDALNHDFFWSDPMPSDLKNMLSTHNTSMFEYLAPPRRRGHMPQQPANQ-NRNPATTSQSEFDRVF 457
BLAST of Cyclin-dependent kinase 9 vs. Ensembl Cavefish
Match: cdk12 (cyclin dependent kinase 12 [Source:NCBI gene;Acc:103040863]) HSP 1 Score: 207.994 bits (528), Expect = 1.413e-58 Identity = 100/217 (46.08%), Postives = 147/217 (67.74%), Query Frame = 1
Query: 118 VDQYEKLQKIGQGTFGEVFKVRDIQTKKYYALKRIKLEQEKEGFPITALREIKILQSLNHPNIVCLREICCSSPTKEKLYKPE--FYLLFDLCDHDLAGLLSDQNMKFSLPQRKSIMKQLFTGIFYLHRNNVIHRDLKAANILIEKHGTLKIADFGLAR-YTIKSPKPDHPPKYTSRVVTMWYRPPEILLNDRHYDKSVDMWGAGCIMAELWTKYPI 759
VD+++ + IG+GT+G+V+K +D T + ALK+++L+ EKEGFPITA+REIKIL+ LNH ++V ++EI K + FYL+F+ DHDL GLL + FS +S M+QL G+ Y H+ N +HRD+K +NIL+ G +K+ADFGLAR Y + +P YT++V+T+WYRPPE+LL + Y ++D+W GCI+ EL+TK PI
Sbjct: 671 VDKFDIIGIIGEGTYGQVYKAKDKDTGELVALKKVRLDNEKEGFPITAIREIKILRQLNHRSVVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVSFSQEHIRSFMRQLMEGLDYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSEESRP-----YTNKVITLWYRPPELLLGEERYSPAIDVWSCGCILGELFTKKPI 882
BLAST of Cyclin-dependent kinase 9 vs. Ensembl Cavefish
Match: cdk12 (cyclin dependent kinase 12 [Source:NCBI gene;Acc:103040863]) HSP 1 Score: 207.994 bits (528), Expect = 1.517e-58 Identity = 100/217 (46.08%), Postives = 147/217 (67.74%), Query Frame = 1
Query: 118 VDQYEKLQKIGQGTFGEVFKVRDIQTKKYYALKRIKLEQEKEGFPITALREIKILQSLNHPNIVCLREICCSSPTKEKLYKPE--FYLLFDLCDHDLAGLLSDQNMKFSLPQRKSIMKQLFTGIFYLHRNNVIHRDLKAANILIEKHGTLKIADFGLAR-YTIKSPKPDHPPKYTSRVVTMWYRPPEILLNDRHYDKSVDMWGAGCIMAELWTKYPI 759
VD+++ + IG+GT+G+V+K +D T + ALK+++L+ EKEGFPITA+REIKIL+ LNH ++V ++EI K + FYL+F+ DHDL GLL + FS +S M+QL G+ Y H+ N +HRD+K +NIL+ G +K+ADFGLAR Y + +P YT++V+T+WYRPPE+LL + Y ++D+W GCI+ EL+TK PI
Sbjct: 682 VDKFDIIGIIGEGTYGQVYKAKDKDTGELVALKKVRLDNEKEGFPITAIREIKILRQLNHRSVVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVSFSQEHIRSFMRQLMEGLDYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSEESRP-----YTNKVITLWYRPPELLLGEERYSPAIDVWSCGCILGELFTKKPI 893
BLAST of Cyclin-dependent kinase 9 vs. Ensembl Cavefish
Match: cdk13 (cyclin dependent kinase 13 [Source:NCBI gene;Acc:103043281]) HSP 1 Score: 207.994 bits (528), Expect = 1.865e-58 Identity = 103/217 (47.47%), Postives = 146/217 (67.28%), Query Frame = 1
Query: 118 VDQYEKLQKIGQGTFGEVFKVRDIQTKKYYALKRIKLEQEKEGFPITALREIKILQSLNHPNIVCLREICCSSPTKE--KLYKPEFYLLFDLCDHDLAGLLSDQNMKFSLPQRKSIMKQLFTGIFYLHRNNVIHRDLKAANILIEKHGTLKIADFGLAR-YTIKSPKPDHPPKYTSRVVTMWYRPPEILLNDRHYDKSVDMWGAGCIMAELWTKYPI 759
VD++E L G+GT+G+V+K RD T + ALK+++L+ EKEGFPITA+REIKIL+ LNH +I+ ++EI K K FYL+F+ DHDL GLL + F+ KS M+QL G+ Y H+ N +HRD+K +NIL+ G +K+ADFGLAR Y + +P YT++V+T+WYRPPE+LL + Y ++D+W GCI+ EL+TK PI
Sbjct: 636 VDKFEILGITGEGTYGQVYKARDKDTAEMVALKKVRLDNEKEGFPITAIREIKILRQLNHKSIINMKEIVTDKEDALDFKNDKGAFYLVFEYMDHDLMGLLESGLVHFNESHIKSFMRQLLEGLDYCHKKNFLHRDIKCSNILLNNKGQIKLADFGLARLYNSEESRP-----YTNKVITLWYRPPELLLGEERYTPAIDVWSCGCILGELFTKKPI 847
BLAST of Cyclin-dependent kinase 9 vs. Ensembl Cavefish
Match: cdk10 (cyclin dependent kinase 10 [Source:NCBI gene;Acc:103043383]) HSP 1 Score: 193.356 bits (490), Expect = 2.134e-57 Identity = 95/219 (43.38%), Postives = 141/219 (64.38%), Query Frame = 1
Query: 112 KHVDQYEKLQKIGQGTFGEVFKVRDIQTKKYYALKRIKLEQEKEGFPITALREIKILQSLNHPNIVCLREICCSSPTKEKLYKPEFYLLFDLCDHDLAGLLSDQNMKFSLPQRKSIMKQLFTGIFYLHRNNVIHRDLKAANILIEKHGTLKIADFGLAR-YTIKSPKPDHPPKYTSRVVTMWYRPPEILLNDRHYDKSVDMWGAGCIMAELWTKYPIMG 765
++V ++EKL +IG+GT+G V++ RD +T + ALK++++++EK+G PI++LREI +L L HPNIV L+E+ S + +L+ C+ DLA LL + FS Q K I+ QL G+ YLH N ++HRDLK +N+L+ G +KIADFGLAR Y + P P T +VVT+WYR PE+LL + ++DMW GCI+AEL P++
Sbjct: 31 RNVKEFEKLNRIGEGTYGIVYRARDTRTNEIVALKKVRMDKEKDGIPISSLREITLLLRLRHPNIVELKEVVVGS------HLESLFLVMSYCEQDLASLLENMQSPFSEAQVKCIVLQLLKGLEYLHHNFILHRDLKVSNLLMTDKGCVKIADFGLARVYGV----PQQP--MTPKVVTLWYRAPELLLGTKTQTTALDMWAVGCILAELLAHKPLLS 237
BLAST of Cyclin-dependent kinase 9 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000850.1 (pep scaffold:Pmarinus_7.0:GL480767:12801:33146:-1 gene:ENSPMAG00000000768.1 transcript:ENSPMAT00000000850.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 211.846 bits (538), Expect = 1.383e-60 Identity = 106/220 (48.18%), Postives = 150/220 (68.18%), Query Frame = 1
Query: 118 VDQYEKLQKIGQGTFGEVFKVRDIQTKKYYALKRIKLEQEKEGFPITALREIKILQSLNHPNIVCLREICCSSPTKE-----KLYKPEFYLLFDLCDHDLAGLLSDQNMKFSLPQRKSIMKQLFTGIFYLHRNNVIHRDLKAANILIEKHGTLKIADFGLAR-YTIKSPKPDHPPKYTSRVVTMWYRPPEILLNDRHYDKSVDMWGAGCIMAELWTKYPI 759
VD+++ + IG+GT+G+V+K +D T + ALK+++L+ EKEGFPITA+REIKIL+ LNH +I+ ++EI KE K K FYL+FD DHDL GLL + FS KS MKQL G+ Y HR N +HRD+K +NIL+ G +K+ADFGLAR Y+ + +P YT++V+T+WYRPPE+LL + Y ++D+W GCI+ EL+T+ PI
Sbjct: 552 VDKFDIIGIIGEGTYGQVYKAKDKDTGELVALKKVRLDNEKEGFPITAIREIKILRQLNHRSIINMKEIVTD---KEDAIDFKKDKGAFYLVFDYMDHDLMGLLESGLVSFSEDHIKSFMKQLMEGLDYCHRKNFLHRDIKCSNILLNNRGHIKLADFGLARLYSSEESRP-----YTNKVITLWYRPPELLLGEERYGPAIDVWSCGCILGELFTRKPI 763
BLAST of Cyclin-dependent kinase 9 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000851.1 (pep scaffold:Pmarinus_7.0:GL480767:12807:33146:-1 gene:ENSPMAG00000000768.1 transcript:ENSPMAT00000000851.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 211.846 bits (538), Expect = 1.417e-60 Identity = 106/220 (48.18%), Postives = 150/220 (68.18%), Query Frame = 1
Query: 118 VDQYEKLQKIGQGTFGEVFKVRDIQTKKYYALKRIKLEQEKEGFPITALREIKILQSLNHPNIVCLREICCSSPTKE-----KLYKPEFYLLFDLCDHDLAGLLSDQNMKFSLPQRKSIMKQLFTGIFYLHRNNVIHRDLKAANILIEKHGTLKIADFGLAR-YTIKSPKPDHPPKYTSRVVTMWYRPPEILLNDRHYDKSVDMWGAGCIMAELWTKYPI 759
VD+++ + IG+GT+G+V+K +D T + ALK+++L+ EKEGFPITA+REIKIL+ LNH +I+ ++EI KE K K FYL+FD DHDL GLL + FS KS MKQL G+ Y HR N +HRD+K +NIL+ G +K+ADFGLAR Y+ + +P YT++V+T+WYRPPE+LL + Y ++D+W GCI+ EL+T+ PI
Sbjct: 553 VDKFDIIGIIGEGTYGQVYKAKDKDTGELVALKKVRLDNEKEGFPITAIREIKILRQLNHRSIINMKEIVTD---KEDAIDFKKDKGAFYLVFDYMDHDLMGLLESGLVSFSEDHIKSFMKQLMEGLDYCHRKNFLHRDIKCSNILLNNRGHIKLADFGLARLYSSEESRP-----YTNKVITLWYRPPELLLGEERYGPAIDVWSCGCILGELFTRKPI 764
BLAST of Cyclin-dependent kinase 9 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000855.1 (pep scaffold:Pmarinus_7.0:GL480767:13986:34488:-1 gene:ENSPMAG00000000768.1 transcript:ENSPMAT00000000855.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 211.46 bits (537), Expect = 1.503e-60 Identity = 106/220 (48.18%), Postives = 150/220 (68.18%), Query Frame = 1
Query: 118 VDQYEKLQKIGQGTFGEVFKVRDIQTKKYYALKRIKLEQEKEGFPITALREIKILQSLNHPNIVCLREICCSSPTKE-----KLYKPEFYLLFDLCDHDLAGLLSDQNMKFSLPQRKSIMKQLFTGIFYLHRNNVIHRDLKAANILIEKHGTLKIADFGLAR-YTIKSPKPDHPPKYTSRVVTMWYRPPEILLNDRHYDKSVDMWGAGCIMAELWTKYPI 759
VD+++ + IG+GT+G+V+K +D T + ALK+++L+ EKEGFPITA+REIKIL+ LNH +I+ ++EI KE K K FYL+FD DHDL GLL + FS KS MKQL G+ Y HR N +HRD+K +NIL+ G +K+ADFGLAR Y+ + +P YT++V+T+WYRPPE+LL + Y ++D+W GCI+ EL+T+ PI
Sbjct: 595 VDKFDIIGIIGEGTYGQVYKAKDKDTGELVALKKVRLDNEKEGFPITAIREIKILRQLNHRSIINMKEIVTD---KEDAIDFKKDKGAFYLVFDYMDHDLMGLLESGLVSFSEDHIKSFMKQLMEGLDYCHRKNFLHRDIKCSNILLNNRGHIKLADFGLARLYSSEESRP-----YTNKVITLWYRPPELLLGEERYGPAIDVWSCGCILGELFTRKPI 806
BLAST of Cyclin-dependent kinase 9 vs. Ensembl Sea Lamprey
Match: cdk2 (cyclin-dependent kinase 2 [Source:ZFIN;Acc:ZDB-GENE-040426-2741]) HSP 1 Score: 180.644 bits (457), Expect = 5.524e-54 Identity = 96/212 (45.28%), Postives = 132/212 (62.26%), Query Frame = 1
Query: 118 VDQYEKLQKIGQGTFGEVFKVRDIQTKKYYALKRIKLEQEKEGFPITALREIKILQSLNHPNIVCLREICCSSPTKEKLYKPEFYLLFDLCDHDLAGLLSDQN-MKFSLPQRKSIMKQLFTGIFYLHRNNVIHRDLKAANILIEKHGTLKIADFGLARYTIKSPKPDHPPKYTSRVVTMWYRPPEILLNDRHYDKSVDMWGAGCIMAELWTK 750
+D ++K++KIG+GT+G V+K R+ T + ALK+I+L+ E EG P TA+REI +L+ LNHPNIV L I S + + YL+F+L D DL + + LP KS + QL GI + H + ++HRDLK N+LI G +K+ADFGLAR P+ YT VVT+WYR PEILL +HY SVD+W GCI AE+ T+
Sbjct: 1 MDNFQKVEKIGEGTYGVVYKARNKLTGEAVALKKIRLDTETEGVPSTAIREISLLRELNHPNIVRLLTIIHS--------EKKLYLVFELLDQDLKKFMDNATPSGIPLPLVKSYLYQLLQGIAFCHSHRILHRDLKPQNLLINAEGAIKLADFGLAR-AFGVPQ----RTYTHEVVTLWYRAPEILLGCKHYSTSVDVWSIGCIFAEMLTR 199
BLAST of Cyclin-dependent kinase 9 vs. Ensembl Sea Lamprey
Match: cdk2 (cyclin-dependent kinase 2 [Source:ZFIN;Acc:ZDB-GENE-040426-2741]) HSP 1 Score: 174.866 bits (442), Expect = 9.265e-52 Identity = 94/212 (44.34%), Postives = 129/212 (60.85%), Query Frame = 1
Query: 118 VDQYEKLQKIGQGTFGEVFKVRDIQTKKYYALKRIKLEQEKEGFPITALREIKILQSLNHPNIVCLREICCSSPTKEKLYKPEFYLLFDLCDHDLAGLLSDQ-NMKFSLPQRKSIMKQLFTGIFYLHRNNVIHRDLKAANILIEKHGTLKIADFGLARYTIKSPKPDHPPKYTSRVVTMWYRPPEILLNDRHYDKSVDMWGAGCIMAELWTK 750
+D ++K++KIG+GT+G V+K R T ALK+I+L+ E EG P TA+REI +L+ LNHPNIV L ++ S + + YL+F+ D DL + + + SLP KS M QL GI + H +HRDLK N+LI G +K+ADFGLAR P YT VVT+WYR PEILL ++Y +VD+W GCI AE+ T+
Sbjct: 1 MDLFQKVEKIGEGTYGVVYKARHKMTGDTVALKKIRLDTETEGVPSTAIREIALLRELNHPNIVRLLDVIHS--------ETKLYLVFEFLDQDLKKYMDNAPPLGISLPLVKSYMHQLLQGIAFCHAQRTLHRDLKPQNLLINADGAIKLADFGLAR-AFGVPL----RTYTHEVVTLWYRAPEILLGCKYYSTAVDVWSLGCIFAEMLTR 199
BLAST of Cyclin-dependent kinase 9 vs. Ensembl Yeast
Match: CTK1 (Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I); phosphorylates both RNA pol II subunit Rpo21p to affect transcription and pre-mRNA 3' end processing, and ribosomal protein Rps2p to increase translational fidelity; required for H3K36 trimethylation but not dimethylation by Set2p; suggested stimulatory role in 80S formation during translation initiation; similar to the Drosophila dCDK12 and human CDK12 and probably CDK13 [Source:SGD;Acc:S000001622]) HSP 1 Score: 209.92 bits (533), Expect = 7.531e-63 Identity = 97/220 (44.09%), Postives = 148/220 (67.27%), Query Frame = 1
Query: 100 LSVLKHVDQYEKLQKIGQGTFGEVFKVRDIQTKKYYALKRIKLEQEKEGFPITALREIKILQSLNHPNIVCLREICCSSPTKEKLYKPEFYLLFDLCDHDLAGLLSDQNMKFSLPQRKSIMKQLFTGIFYLHRNNVIHRDLKAANILIEKHGTLKIADFGLARYTIKSPKPDHPPKYTSRVVTMWYRPPEILLNDRHYDKSVDMWGAGCIMAELWTKYPI 759
L+ + Y ++ ++G+GT+G+V+K ++ T+K ALK+++L+ E+EGFPIT++REIK+LQS +HPN+ ++EI S + Y++F+ D+DL+GLL ++ ++ S Q K + KQL G+ YLH N ++HRD+K +NILI+ G LKI DFGLAR K + YT+RV+T+WYRPPE+LL +Y VDMWG GC++ EL+ K I
Sbjct: 174 LTQQRSTSVYLRIMQVGEGTYGKVYKAKNTNTEKLVALKKLRLQGEREGFPITSIREIKLLQSFDHPNVSTIKEIMVES-------QKTVYMIFEYADNDLSGLLLNKEVQISHSQCKHLFKQLLLGMEYLHDNKILHRDVKGSNILIDNQGNLKITDFGLAR------KMNSRADYTNRVITLWYRPPELLLGTTNYGTEVDMWGCGCLLVELFNKTAI 380
BLAST of Cyclin-dependent kinase 9 vs. Ensembl Yeast
Match: SGV1 (Cyclin (Bur2p)-dependent protein kinase; part of the BUR kinase complex which functions in transcriptional regulation; phosphorylates the carboxy-terminal domain (CTD) of Rpo21p and the C-terminal repeat domain of Spt5p; recruits Spt6p to the CTD at the onset of transcription; regulated by Cak1p; similar to metazoan CDK9 proteins [Source:SGD;Acc:S000006365]) HSP 1 Score: 176.407 bits (446), Expect = 1.660e-49 Identity = 96/227 (42.29%), Postives = 141/227 (62.11%), Query Frame = 1
Query: 121 DQYEKLQKIGQGTFGEVFKVRDIQTKKYYALKRIKLEQEKEGFPITALREIKILQSLNHPNIVCLREIC------CSSPTKEKLYKPEFYLLFDLCDHDLAGLLSDQNMKFSLPQRKSIMKQLFTGIFYLHRNNVIHRDLKAANILIEKHGTLKIADFGLAR-YTIKSPKPDHP------PKYTSRVVTMWYRPPEILLNDRHYDKSVDMWGAGCIMAELWTKYPIM 762
+ Y + +K+GQGTFGEV+K ++T++ A+K+I + EK+ FPITA REI IL+ LNH NI+ L E+ ++ L+K FY++ DL+G+L + + + K++M Q+ G+ Y+H +HRD+K ANILI+ +G LK+ADFGLAR Y P +P KYTS VVT WYR PE++L D+ Y +VD+WG GC+ AE + K PI+
Sbjct: 58 NHYREDEKLGQGTFGEVYKGIHLETQRQVAMKKIIVSVEKDLFPITAQREITILKRLNHKNIIKLIEMVYDHSPDITNAASSNLHK-SFYMILPYMVADLSGVLHNPRINLEMCDIKNMMLQILEGLNYIHCAKFMHRDIKTANILIDHNGVLKLADFGLARLYYGCPPNLKYPGGAGSGAKYTSVVVTRWYRAPELVLGDKQYTTAVDIWGVGCVFAEFFEKKPIL 283
BLAST of Cyclin-dependent kinase 9 vs. Ensembl Yeast
Match: CDC28 (Cyclin-dependent kinase (CDK) catalytic subunit; master regulator of mitotic and meiotic cell cycles; alternately associates with G1, S, G2/M phase cyclins, which provide substrate specificity; regulates metabolism, basal transcription, chromosome dynamics, growth and morphogenesis; transcript induction in osmostress involves antisense RNA; human homologs CDK1, CDK2, CDK3 can complement yeast conditional cdc28 mutants; human CDK1, CDK2 can complement yeast cdc28 null mutant [Source:SGD;Acc:S000000364]) HSP 1 Score: 160.229 bits (404), Expect = 2.203e-46 Identity = 92/220 (41.82%), Postives = 125/220 (56.82%), Query Frame = 1
Query: 124 QYEKLQKIGQGTFGEVFKVRDI---QTKKYYALKRIKLEQEKEGFPITALREIKILQSLNHPNIVCLREICCSSPTKEKLYKPEFYLLFDLCDHDL----AGLLSDQNMKFSLPQRKSIMKQLFTGIFYLHRNNVIHRDLKAANILIEKHGTLKIADFGLARYTIKSPKPDHPPKYTSRVVTMWYRPPEILLNDRHYDKSVDMWGAGCIMAELWTKYPIM 762
Y++L+K+G+GT+G V+K D+ Q ++ ALK+I+LE E EG P TA+REI +L+ L NIV L +I S K YL+F+ D DL G+ DQ + + K M QL GI Y H + ++HRDLK N+LI K G LK+ DFGLAR + YT +VT+WYR PE+LL + Y VD W GCI AE+ + PI
Sbjct: 7 NYKRLEKVGEGTYGVVYKALDLRPGQGQRVVALKKIRLESEDEGVPSTAIREISLLKELKDDNIVRLYDIVHSDAHK-------LYLVFEFLDLDLKRYMEGIPKDQPLGADIV--KKFMMQLCKGIAYCHSHRILHRDLKPQNLLINKDGNLKLGDFGLARAFGVPLR-----AYTHEIVTLWYRAPEVLLGGKQYSTGVDTWSIGCIFAEMCNRKPIF 212
BLAST of Cyclin-dependent kinase 9 vs. Ensembl Yeast
Match: PHO85 (Cyclin-dependent kinase; has ten cyclin partners; involved in regulating the cellular response to nutrient levels and environmental conditions and progression through the cell cycle; human lissencephaly-associated homolog CDK5 functionally complements null mutation [Source:SGD;Acc:S000005952]) HSP 1 Score: 149.058 bits (375), Expect = 4.404e-42 Identity = 85/217 (39.17%), Postives = 125/217 (57.60%), Query Frame = 1
Query: 124 QYEKLQKIGQGTFGEVFKVRDIQTKKYYALKRIKLEQEKEGFPITALREIKILQSLNHPNIVCLREICCSSPTKEKLYKPEFYLLFDLCDHDLAGLLSDQNMK-----FSLPQRKSIMKQLFTGIFYLHRNNVIHRDLKAANILIEKHGTLKIADFGLARYTIKSPKPDHPPKYTSRVVTMWYRPPEILLNDRHYDKSVDMWGAGCIMAELWTKYPI 759
Q+++L+K+G GT+ V+K + T Y ALK +KL+ E EG P TA+REI +++ L H NIV L ++ T+ KL L+F+ D+DL + + + L K QL G+ + H N ++HRDLK N+LI K G LK+ DFGLAR P ++S VVT+WYR P++L+ R Y S+D+W GCI+AE+ T P+
Sbjct: 6 QFKQLEKLGNGTYATVYKGLNKTTGVYVALKEVKLDSE-EGTPSTAIREISLMKELKHENIVRLYDVIH---TENKLT-----LVFEFMDNDLKKYMDSRTVGNTPRGLELNLVKYFQWQLLQGLAFCHENKILHRDLKPQNLLINKRGQLKLGDFGLAR-AFGIPVN----TFSSEVVTLWYRAPDVLMGSRTYSTSIDIWSCGCILAEMITGKPL 208
BLAST of Cyclin-dependent kinase 9 vs. Ensembl Yeast
Match: KIN28 (Serine/threonine protein kinase, subunit of transcription factor TFIIH; involved in transcription initiation at RNA polymerase II promoters; phosphorylates Ser5 residue of the PolII C-terminal domain (CTD) at gene promoters; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000002266]) HSP 1 Score: 140.584 bits (353), Expect = 5.772e-39 Identity = 75/213 (35.21%), Postives = 118/213 (55.40%), Query Frame = 1
Query: 124 QYEKLQKIGQGTFGEVFKVRDIQTKKYYALKRIKLEQEKEGFPITALREIKILQSLNHPNIVCLREICCSSPTKEKLYKPEFYLLFDLCDHDLAGLLSDQNMKFSLPQRKSIMKQLFTGIFYLHRNNVIHRDLKAANILIEKHGTLKIADFGLARYTIKSPKPDHPPKYTSRVVTMWYRPPEILLNDRHYDKSVDMWGAGCIMAELWTKYPIM 762
+Y K +K+G+GT+ V+ T + A+K IK + K+G ++A+RE+K LQ + HPN++ L +I + L+ + DL ++ D+++ F+ K+ M G+++ HRN ++HRDLK N+L G +K+ADFGLAR P P TS VVT WYR PE+L +HY ++D+W G I AEL + P +
Sbjct: 6 EYTKEKKVGEGTYAVVYLGCQHSTGRKIAIKEIKTSEFKDGLDMSAIREVKYLQEMQHPNVIELIDIFMAYDN--------LNLVLEFLPTDLEVVIKDKSILFTPADIKAWMLMTLRGVYHCHRNFILHRDLKPNNLLFSPDGQIKVADFGLARAI---PAPHE--ILTSNVVTRWYRAPELLFGAKHYTSAIDIWSVGVIFAELMLRIPYL 205
BLAST of Cyclin-dependent kinase 9 vs. Ensembl Nematostella
Match: EDO34765 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SNE8]) HSP 1 Score: 251.521 bits (641), Expect = 6.977e-82 Identity = 122/216 (56.48%), Postives = 162/216 (75.00%), Query Frame = 1
Query: 118 VDQYEKLQKIGQGTFGEVFKVRDIQT-KKYYALKRIKLEQEKEGFPITALREIKILQSLNHPNIVCLREICCSSPTKEKLYKPEFYLLFDLCDHDLAGLLSDQNMKFSLPQRKSIMKQLFTGIFYLHRNNVIHRDLKAANILIEKHGTLKIADFGLARYTIKSPKPDHPPKYTSRVVTMWYRPPEILLNDRHYDKSVDMWGAGCIMAELWTKYPIM 762
V +YE+ KIGQGTFGEVFK ++ + K+ ALK++ ++ EKEGFPITALREIKILQ LNH N+V L EIC + K YL+F+ C+HDLAGLL++Q +KFS P+ K IM+ L ++++H N ++HRD+KAANILI K+G LK+A+FGLAR I K + +YT+RVVT+WYRPPE+LL +R+Y +D+WGAGCIMAELWT+ PIM
Sbjct: 14 VSKYERQAKIGQGTFGEVFKAKNRKNPKEIVALKKVLMDNEKEGFPITALREIKILQLLNHENVVKLLEICRTKAQPFNRNKASIYLVFEFCEHDLAGLLNNQAVKFSPPEMKKIMQMLLNALYFIHSNKILHRDMKAANILITKNGVLKLAEFGLAR-AIHINK-EQKQRYTNRVVTLWYRPPELLLGERNYGPPIDLWGAGCIMAELWTRTPIM 227 HSP 2 Score: 71.633 bits (174), Expect = 6.977e-82 Identity = 56/142 (39.44%), Postives = 83/142 (58.45%), Query Frame = 3
Query: 762 GESEIHQLKLIINLCGSINEESWPGVSKLEAF-KRLERTNHKRFVRQQLLKVIDCHSAVXXXXXXXXXXXXXXXTADIALMHEFFYEDPPAGDLSDF--SNAGSFYEFLSNQKKPNQSKANYLNRDAMKET---SGILDRIY 1169
G +E HQL LI +LCGSI E WPGV KLE F K + + KR V+++L + H+A+DLIDK+L LDP R+ AD AL H++F+ DP DL+ + S +E+L+ ++ Q + + + SG DR++
Sbjct: 229 GNTEQHQLTLISHLCGSITPEVWPGVDKLELFDKMVLPSGQKRRVKERLRMYVKDHNALDLIDKMLSLDPGPRIDADSALNHDYFWTDPMPTDLTRTLAMHNQSMFEYLAPPRRGGQRQPAPPRPGPTQPSIVQSGTYDRVF 370
BLAST of Cyclin-dependent kinase 9 vs. Ensembl Nematostella
Match: EDO46173 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RQW1]) HSP 1 Score: 204.527 bits (519), Expect = 8.356e-63 Identity = 99/215 (46.05%), Postives = 143/215 (66.51%), Query Frame = 1
Query: 127 YEKLQKIGQGTFGEVFKVRDIQTKKYYALKRIKLEQEKEGFPITALREIKILQSLNHPNIVCLREICCSSPTKEKLYKPE--FYLLFDLCDHDLAGLLSDQNMKFSLPQRKSIMKQLFTGIFYLHRNNVIHRDLKAANILIEKHGTLKIADFGLAR-YTIKSPKPDHPPKYTSRVVTMWYRPPEILLNDRHYDKSVDMWGAGCIMAELWTKYPIM 762
++ +++IG+GT+G+V+K +D T + LK+++ + EKEGFPITA+REIKIL LNHPNI+ L+EI P K + FYL+F+ DHDL GLL + + KS ++QL G+ Y H+ N +HRD+K +NIL+ G +K+ADFGLAR Y +P YT++V+T+WYRPPE+LL + Y +D+W GCI+AEL+TK PI
Sbjct: 2 FDIIEQIGEGTYGQVYKAKDKITGELVGLKKVRTDNEKEGFPITAVREIKILCQLNHPNIINLKEIVTDKPNALDFRKDKGAFYLVFEYMDHDLMGLLESGLVHLTEDHIKSFIRQLLDGLNYCHKKNFLHRDIKCSNILLNNKGEIKLADFGLARLYEADERRP-----YTNKVITLWYRPPELLLGEERYGPGIDIWSVGCILAELFTKKPIF 211
BLAST of Cyclin-dependent kinase 9 vs. Ensembl Nematostella
Match: EDO29995 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T226]) HSP 1 Score: 182.185 bits (461), Expect = 2.136e-53 Identity = 93/222 (41.89%), Postives = 134/222 (60.36%), Query Frame = 1
Query: 118 VDQYEKLQKIGQGTFGEVFKVRDIQTKKYYALKRIKLEQEKEGFPITALREIKILQSLNHPNIVCLREICCSSPTKEKLYKPEFYLLFDLCDHDLAGLLSDQNMKFSLPQRKSIMKQLFTGIFYLHRNNVIHRDLKAANILIEKHGTLKIADFGLARYTIKSPKPDHPPKYTSRVVTMWYRPPEILLNDRHYDKSVDMWGAGCIMAELWTKYPIMGRVKYIN 783
V ++EKL +IG+GT+G V++ +D ++ K ALK++++EQE++G PI+ LREI +L +L H NIV L E+ + +L + C+ D+A LL + + FS Q K +M QL G YLH + ++HRDLK +N+L+ G LKIADFGLAR KP T VVT+WYR PE+LL + + +VDMW GCI EL P++ IN
Sbjct: 33 VAEFEKLNRIGEGTYGIVYRAKDTKSGKIVALKKVRMEQERDGIPISGLREITLLLNLRHENIVQLLEVVVGK------HLDSLFLSMEYCEQDIASLLDNMSCPFSEAQIKCLMIQLLEGTKYLHEHFIVHRDLKVSNLLLTGKGVLKIADFGLARTFGYPYKP-----MTPVVVTLWYRSPELLLGAKVHTTAVDMWAVGCIFGELLGNKPLLAGKSEIN 243
BLAST of Cyclin-dependent kinase 9 vs. Ensembl Nematostella
Match: EDO41403 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S4F0]) HSP 1 Score: 175.252 bits (443), Expect = 1.030e-51 Identity = 94/217 (43.32%), Postives = 134/217 (61.75%), Query Frame = 1
Query: 118 VDQYEKLQKIGQGTFGEVFKVRDIQTKKYYALKRIKLEQEKEGFPITALREIKILQSLNHPNIVCLREICCSSPTKEKLYKPEFYLLFDLCDHDL---AGLLSDQNMKFSLPQRKSIMKQLFTGIFYLHRNNVIHRDLKAANILIEKHGTLKIADFGLAR---YTIKSPKPDHPPKYTSRVVTMWYRPPEILLNDRHYDKSVDMWGAGCIMAELWTK 750
++ +EK++KIG+GT+G V+K RD T + ALK+I+L+ E EG P TA+REI +L+ LNHPN+V L ++ + + YL+F+ DL L + SL KS + QL +G+ Y H + V+HRDLK N+LI+K+G +K+ADFGLAR ++S YT VVT+WYR PEILL R+Y VD+W GCI AE+ T+
Sbjct: 1 MENFEKVEKIGEGTYGVVYKARDKTTGRMVALKKIRLDTESEGVPSTAIREISLLKELNHPNVVSLLDVVHN--------QKSLYLVFEFLSQDLKKYMDCLPPSGISTSL--IKSYVYQLLSGVAYCHSHRVLHRDLKPQNLLIDKNGAIKLADFGLARAFGVPVRS--------YTHEVVTLWYRAPEILLGSRYYATPVDVWSIGCIFAEMKTR 199
BLAST of Cyclin-dependent kinase 9 vs. Ensembl Nematostella
Match: EDO49420 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RGF7]) HSP 1 Score: 172.17 bits (435), Expect = 1.764e-50 Identity = 90/208 (43.27%), Postives = 132/208 (63.46%), Query Frame = 1
Query: 124 QYEKLQKIGQGTFGEVFKVRDIQTKKYYALKRIKLEQEKEGFPITALREIKILQSLNHPNIVCLREICCSSPTKEKLYKPEFYLLFDLCDHDLAGLLSDQNMKFSLPQRKSIMKQLFTGIFYLHRNNVIHRDLKAANILIEKHGTLKIADFGLAR-YTIKSPKPDHPPK-YTSRVVTMWYRPPEILLNDRHYDKSVDMWGAGCIMAEL 741
+Y+KL+KIG+GT+G VFK ++ +T++ ALKR++L+ + EG P +ALREI +L+ L H NIV L ++ S + + L+F+ CD DL + KS M QL G+ + H +NV+HRDLK N+LI K G LK+ADFGLAR + I P + +++ VVT+WYRPP++L+ + Y S+DMW AGCI AE+
Sbjct: 3 KYDKLEKIGEGTYGTVFKGKNKETREILALKRVRLDDDDEGVPSSALREICLLKELKHNNIVRLYDVLHS--------EKKLTLVFEFCDQDLKKYFDSCQGEVDASVVKSFMFQLLRGLAFCHSHNVLHRDLKPQNLLINKDGELKLADFGLARAFGI-------PVRCFSAEVVTLWYRPPDVLMGAKLYSTSIDMWSAGCIFAEM 195
BLAST of Cyclin-dependent kinase 9 vs. Ensembl Medaka
Match: cdk9 (cyclin dependent kinase 9 [Source:NCBI gene;Acc:101158180]) HSP 1 Score: 270.396 bits (690), Expect = 9.539e-87 Identity = 125/213 (58.69%), Postives = 160/213 (75.12%), Query Frame = 1
Query: 124 QYEKLQKIGQGTFGEVFKVRDIQTKKYYALKRIKLEQEKEGFPITALREIKILQSLNHPNIVCLREICCSSPTKEKLYKPEFYLLFDLCDHDLAGLLSDQNMKFSLPQRKSIMKQLFTGIFYLHRNNVIHRDLKAANILIEKHGTLKIADFGLARYTIKSPKPDHPPKYTSRVVTMWYRPPEILLNDRHYDKSVDMWGAGCIMAELWTKYPIM 762
+YEK+ KIGQGTFGEVFK + T K ALK++ +E EKEGFPITALREIKILQ L H N+V L EIC + T+ YK YL+FD C+HDLAGLLS+ N+KF+L + K +M+ L G++Y+HRN ++HRD+KAAN+LI + G LK+ADFGLAR K +YT+RVVT+WYRPPE+LL +R Y +D+WGAGCIMAE+WT+ PIM
Sbjct: 39 KYEKMAKIGQGTFGEVFKAKHRTTGKKVALKKVLMENEKEGFPITALREIKILQLLKHENVVNLIEICRTKATQFNRYKGSIYLVFDFCEHDLAGLLSNANVKFTLAEIKKVMQMLLNGLYYIHRNKILHRDMKAANVLITRDGVLKLADFGLAR-AFSLAKNSQGNRYTNRVVTLWYRPPELLLGERDYGPPIDLWGAGCIMAEMWTRSPIM 250 HSP 2 Score: 65.0846 bits (157), Expect = 3.571e-11 Identity = 57/148 (38.51%), Postives = 84/148 (56.76%), Query Frame = 3
Query: 762 GESEIHQLKLIINLCGSINEESWPGV-SKLEAFKRLE-RTNHKRFVRQQLLKVIDCHSAVXXXXXXXXXXXXXXXTADIALMHEFFYEDPPAGDLSDF--SNAGSFYEFLS--------NQKKPNQSKANYLNRDAMKETSGILDRIY 1169
G +E HQL LI LCGSI E WPGV K E ++++E KR V+ +L + A+DLIDKLL+LDP +R+ +D AL H+FF+ DP DL + ++ S +E+L+ Q++PNQ NR+ + DR++
Sbjct: 252 GNTEQHQLTLISQLCGSITAEVWPGVDKKYELYQKMELPKGQKRKVKDRLKAYVKDAYALDLIDKLLVLDPAQRIDSDDALNHDFFWSDPMPSDLKNMLSTHNTSMFEYLAPPRRRGHIPQQQPNQ------NRNPATTSQTEFDRVF 393
BLAST of Cyclin-dependent kinase 9 vs. Ensembl Medaka
Match: cdk12 (cyclin-dependent kinase 12 [Source:NCBI gene;Acc:101169207]) HSP 1 Score: 207.608 bits (527), Expect = 2.401e-58 Identity = 100/217 (46.08%), Postives = 148/217 (68.20%), Query Frame = 1
Query: 118 VDQYEKLQKIGQGTFGEVFKVRDIQTKKYYALKRIKLEQEKEGFPITALREIKILQSLNHPNIVCLREICCSSPTKEKLYKPE--FYLLFDLCDHDLAGLLSDQNMKFSLPQRKSIMKQLFTGIFYLHRNNVIHRDLKAANILIEKHGTLKIADFGLAR-YTIKSPKPDHPPKYTSRVVTMWYRPPEILLNDRHYDKSVDMWGAGCIMAELWTKYPI 759
VD+++ + IG+GT+G+V+K +D T + ALK+++L+ EKEGFPITA+REIKIL+ L H ++V ++EI K + FYL+F+ DHDL GLL ++FS +S M+QL G+ Y H+NN +HRD+K +NIL+ G +K+ADFGLAR Y + +P YT++V+T+WYRPPE+LL + Y ++D+W GCI+ EL+TK PI
Sbjct: 700 VDKFDIIGIIGEGTYGQVYKAKDKDTGELVALKKVRLDNEKEGFPITAIREIKILRQLKHRSVVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVQFSHEHVRSFMRQLMEGLDYCHKNNFLHRDIKCSNILLNNRGQIKLADFGLARLYNSEESRP-----YTNKVITLWYRPPELLLGEERYSPAIDVWSCGCILGELFTKKPI 911
BLAST of Cyclin-dependent kinase 9 vs. Ensembl Medaka
Match: cdk13 (cyclin dependent kinase 13 [Source:NCBI gene;Acc:101169150]) HSP 1 Score: 204.142 bits (518), Expect = 3.133e-57 Identity = 100/217 (46.08%), Postives = 145/217 (66.82%), Query Frame = 1
Query: 118 VDQYEKLQKIGQGTFGEVFKVRDIQTKKYYALKRIKLEQEKEGFPITALREIKILQSLNHPNIVCLREICCSSPTKEKLY--KPEFYLLFDLCDHDLAGLLSDQNMKFSLPQRKSIMKQLFTGIFYLHRNNVIHRDLKAANILIEKHGTLKIADFGLAR-YTIKSPKPDHPPKYTSRVVTMWYRPPEILLNDRHYDKSVDMWGAGCIMAELWTKYPI 759
VD++E + G+GT+G+V+K +D T + ALK+++L+ EKEGFPITA+REIKIL+ LNH +I+ ++EI K FYL+F+ DHDL GLL + F+ KS M+QL G+ Y H+ N +HRD+K +NIL+ G +K+ADFGLAR Y + +P YT++V+T+WYRPPE+LL + Y ++D+W GCI+ EL+TK PI
Sbjct: 633 VDKFEIIGITGEGTYGQVYKAKDKDTGEMVALKKVRLDNEKEGFPITAIREIKILRQLNHKSIINMKEIVTDKEDALDFRNDKGAFYLVFEYMDHDLMGLLESGLVHFNESHIKSFMRQLLEGLDYCHKKNFLHRDIKCSNILLNNRGQIKLADFGLARLYNSEESRP-----YTNKVITLWYRPPELLLGEERYTPAIDVWSCGCILGELFTKKPI 844
BLAST of Cyclin-dependent kinase 9 vs. Ensembl Medaka
Match: cdk10 (cyclin dependent kinase 10 [Source:NCBI gene;Acc:101169200]) HSP 1 Score: 192.586 bits (488), Expect = 4.092e-57 Identity = 96/218 (44.04%), Postives = 139/218 (63.76%), Query Frame = 1
Query: 112 KHVDQYEKLQKIGQGTFGEVFKVRDIQTKKYYALKRIKLEQEKEGFPITALREIKILQSLNHPNIVCLREICCSSPTKEKLYKPEFYLLFDLCDHDLAGLLSDQNMKFSLPQRKSIMKQLFTGIFYLHRNNVIHRDLKAANILIEKHGTLKIADFGLAR-YTIKSPKPDHPPKYTSRVVTMWYRPPEILLNDRHYDKSVDMWGAGCIMAELWTKYPIM 762
+ V ++EKL +IG+GT+G V++ RD ++ + ALK++++++EK+G PI++LREI +L L HPNIV L+E+ S + +L+ C+ DLA LL + FS Q K I+ QL G+ YLH N +IHRDLK +N+L+ G +KIADFGLAR Y I P T RVVT+WYR PE+LL + ++DMW GCI+AEL P++
Sbjct: 35 RSVREFEKLNRIGEGTYGIVYRARDTRSNEIVALKKVRMDKEKDGIPISSLREITLLLRLRHPNIVELKEVVVGSQLE------SLFLVMSYCEQDLASLLENMQTPFSETQVKCIVLQLLKGLEYLHHNFIIHRDLKVSNLLMTDKGYVKIADFGLARMYGIPQ------PLMTPRVVTLWYRAPEVLLGTKIQTTALDMWAVGCILAELLAHKPLL 240
BLAST of Cyclin-dependent kinase 9 vs. Ensembl Medaka
Match: cdk11b (cyclin-dependent kinase 11B [Source:NCBI gene;Acc:101154777]) HSP 1 Score: 186.422 bits (472), Expect = 7.980e-52 Identity = 94/222 (42.34%), Postives = 136/222 (61.26%), Query Frame = 1
Query: 94 PNLSVLKHVDQYEKLQKIGQGTFGEVFKVRDIQTKKYYALKRIKLEQEKEGFPITALREIKILQSLNHPNIVCLREICCSSPTKEKLYKPEFYLLFDLCDHDLAGLLSDQNMKFSLPQRKSIMKQLFTGIFYLHRNNVIHRDLKAANILIEKHGTLKIADFGLARYTIKSPKPDHPPKYTSRVVTMWYRPPEILLNDRHYDKSVDMWGAGCIMAELWTKYPI 759
P + + V++++ L +I +GT+G V++ +D +T + ALKR+K+E+EKEGFPIT+LREI + HPNIV +REI S + Y++ + +HDL L+ F + K++M QL G+ +LH N ++HRDLK +N+L+ G LKI DFGLAR KP YT VVT+WYR PE+LL + Y +VDMW GCI EL T+ P+
Sbjct: 365 PAVQGCRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVREIVVGSNMD------KIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVRHLHDNWILHRDLKTSNLLLSHKGILKIGDFGLAREYGSPLKP-----YTPIVVTLWYRSPELLLGAKEYSTAVDMWSVGCIFGELLTQKPL 575
BLAST of Cyclin-dependent kinase 9 vs. Planmine SMEST
Match: SMESG000028783.1 (SMESG000028783.1) HSP 1 Score: 527.709 bits (1358), Expect = 0.000e+0 Identity = 252/252 (100.00%), Postives = 252/252 (100.00%), Query Frame = 1
Query: 7 MEDFNKLYSEVINDISFGLQDFFKRIQSDPNLSVLKHVDQYEKLQKIGQGTFGEVFKVRDIQTKKYYALKRIKLEQEKEGFPITALREIKILQSLNHPNIVCLREICCSSPTKEKLYKPEFYLLFDLCDHDLAGLLSDQNMKFSLPQRKSIMKQLFTGIFYLHRNNVIHRDLKAANILIEKHGTLKIADFGLARYTIKSPKPDHPPKYTSRVVTMWYRPPEILLNDRHYDKSVDMWGAGCIMAELWTKYPIM 762
MEDFNKLYSEVINDISFGLQDFFKRIQSDPNLSVLKHVDQYEKLQKIGQGTFGEVFKVRDIQTKKYYALKRIKLEQEKEGFPITALREIKILQSLNHPNIVCLREICCSSPTKEKLYKPEFYLLFDLCDHDLAGLLSDQNMKFSLPQRKSIMKQLFTGIFYLHRNNVIHRDLKAANILIEKHGTLKIADFGLARYTIKSPKPDHPPKYTSRVVTMWYRPPEILLNDRHYDKSVDMWGAGCIMAELWTKYPIM
Sbjct: 1 MEDFNKLYSEVINDISFGLQDFFKRIQSDPNLSVLKHVDQYEKLQKIGQGTFGEVFKVRDIQTKKYYALKRIKLEQEKEGFPITALREIKILQSLNHPNIVCLREICCSSPTKEKLYKPEFYLLFDLCDHDLAGLLSDQNMKFSLPQRKSIMKQLFTGIFYLHRNNVIHRDLKAANILIEKHGTLKIADFGLARYTIKSPKPDHPPKYTSRVVTMWYRPPEILLNDRHYDKSVDMWGAGCIMAELWTKYPIM 252 HSP 2 Score: 248.054 bits (632), Expect = 0.000e+0 Identity = 136/136 (100.00%), Postives = 136/136 (100.00%), Query Frame = 3
Query: 762 GESEIHQLKLIINLCGSINEESWPGVSKLEAFKRLERTNHKRFVRQQLLKVIDCHSAVXXXXXXXXXXXXXXXTADIALMHEFFYEDPPAGDLSDFSNAGSFYEFLSNQKKPNQSKANYLNRDAMKETSGILDRIY 1169
GESEIHQLKLIINLCGSINEESWPGVSKLEAFKRLERTNHKRFVRQQLLKVIDCHSAVDLIDKLLLLDPRKRLTADIALMHEFFYEDPPAGDLSDFSNAGSFYEFLSNQKKPNQSKANYLNRDAMKETSGILDRIY
Sbjct: 254 GESEIHQLKLIINLCGSINEESWPGVSKLEAFKRLERTNHKRFVRQQLLKVIDCHSAVDLIDKLLLLDPRKRLTADIALMHEFFYEDPPAGDLSDFSNAGSFYEFLSNQKKPNQSKANYLNRDAMKETSGILDRIY 389
BLAST of Cyclin-dependent kinase 9 vs. Planmine SMEST
Match: SMESG000013406.1 (SMESG000013406.1) HSP 1 Score: 279.641 bits (714), Expect = 2.162e-90 Identity = 135/257 (52.53%), Postives = 175/257 (68.09%), Query Frame = 1
Query: 7 MEDFNKLYSEVINDISFGLQDFFKRIQSDPNLSVLKHVDQYEKLQKIGQGTFGEVFKVRDIQTKKYYALKRIKLEQEKEGFPITALREIKILQSLNHPNIVCLREICCSSPTKEKLYKPEFYLLFDLCDHDLAGLLSDQNMKFSLPQRKSIMKQLFTGIFYLHRNNVIHRDLKAANILIEKHGTLKIADFGLARYTIKSPKPDHPPKYTSRVVTMWYRPPEILLNDRHYDKSVDMWGAGCIMAELWTKYPI-MGRVK 774
+ +F Y ++ +D+ G +I LK+V Y K KIGQGTFGEVFK++ I+T K YALKRIK E E EGFPIT+LRE+KILQ+L H NIV L E+C ++PT +PEF+L+FDLCDHDL+G+LSD +F+L QRK+I+ + G+ YLHR +IHRD+K +NILI+ G +KI DFGLAR K ++T RVVT+WYRPPEILLN YD SVDMW AGC+ AELW + + MGR +
Sbjct: 2 ITEFQNFYDDIYDDLKEGSDIILSKINYKTTKFSLKNVSAYIKEDKIGQGTFGEVFKMKHIETGKLYALKRIKYETELEGFPITSLREVKILQALKHDNIVKLHEVCWNNPTPSSKNRPEFFLVFDLCDHDLSGILSDTQFQFNLAQRKTIILHILKGLHYLHRKEIIHRDIKTSNILIDHQGIVKIGDFGLARLLTSQVKHMGKARFTGRVVTLWYRPPEILLNYNDYDCSVDMWSAGCVFAELWKREALMMGRTE 258 HSP 2 Score: 72.7886 bits (177), Expect = 2.162e-90 Identity = 52/105 (49.52%), Postives = 66/105 (62.86%), Query Frame = 3
Query: 762 GESEIHQLKLIINLCGSINEESWPGVSKLEAFKRLERTNHKRFVRQQLLKVIDCHSAVXXXXXXXXXXXXXXXTADIALMHEFFYEDPPAGDLSDFSNAGSFYEF 1076
G +E+ QL LI LCGSI E+ WPGVSK + K+L N R V + L ID + AVDLIDKLL+L+P+ R+TA+ AL HEFF +P DL G YE+
Sbjct: 255 GRTELAQLALITKLCGSITEKVWPGVSKYDELKKLTLKNEPRNVLKSLGAFIDNNLAVDLIDKLLILNPKDRITANEALGHEFFKTEPLCADLRQMKIKGHCYEY 359
BLAST of Cyclin-dependent kinase 9 vs. Planmine SMEST
Match: SMESG000078149.1 (SMESG000078149.1) HSP 1 Score: 203.371 bits (516), Expect = 1.006e-58 Identity = 98/213 (46.01%), Postives = 141/213 (66.20%), Query Frame = 1
Query: 112 KHVDQYEKLQKIGQGTFGEVFKVRDIQTKKYYALKRIKLEQEKEGFPITALREIKILQSLNHPNIVCLREICCSSPTKEKLYKPEFYLLFDLCDHDLAGLLSDQNMKFSLPQRKSIMKQLFTGIFYLHRNNVIHRDLKAANILIEKHGTLKIADFGLARYTIKSPKPDHPPKYTSRVVTMWYRPPEILLNDRHYDKSVDMWGAGCIMAELWTK 750
+ V ++ + ++G+GT+G VFK D QT ALK+I+LE E+EGFPIT +REIKIL LNHPNI+ L E+ +K FYL+F+ DHDL G+L D + + Q SIMKQ+ +GI Y H+ +HRD+K++NIL+ G +KIADFGLAR ++ P YT++V+T+WYR PE+LL + Y +++D+W GCIM EL+ +
Sbjct: 157 RSVKSFKIIAEVGEGTYGHVFKAIDRQTNAMKALKKIRLENEREGFPITTVREIKILHKLNHPNIIYLNEVVTDYDSKSNSKVKGFYLVFEYMDHDLYGIL-DSGITLNENQIASIMKQIISGICYCHKRKFLHRDIKSSNILVNNKGEVKIADFGLAR-KFEADNSKRP--YTNKVITLWYRAPELLLGEEIYGEAIDVWSIGCIMGELFVR 365
BLAST of Cyclin-dependent kinase 9 vs. Planmine SMEST
Match: SMESG000057162.1 (SMESG000057162.1) HSP 1 Score: 201.83 bits (512), Expect = 6.151e-57 Identity = 104/214 (48.60%), Postives = 139/214 (64.95%), Query Frame = 1
Query: 112 KHVDQYEKLQKIGQGTFGEVFKVRDIQTKKYYALKRIKLEQEKEGFPITALREIKILQSLNHPNIVCLREICC--SSPTKEKLYKPEFYLLFDLCDHDLAGLLSDQNMKFSLPQRKSIMKQLFTGIFYLHRNNVIHRDLKAANILIEKHGTLKIADFGLARYTIKSPKPDHPPKYTSRVVTMWYRPPEILLNDRHYDKSVDMWGAGCIMAELWT 747
+ V + + K+G+GT+G VFK DIQT + ALK+++LE EKEGFPITA+REIKIL L H NIV L EI + K K FYL+FD DHDL G+L +++ + Q SI KQL GI Y H N +HRD+K +NIL+ G +K+ADFGLAR I D YT++V+T+WYRPPE+LL + Y ++D+W GCI+ EL+T
Sbjct: 350 RSVSAFRFIDKVGEGTYGHVFKAEDIQTGELKALKKVRLENEKEGFPITAIREIKILMQLVHANIVNLCEIVTDIDNALDFKKDKGAFYLVFDYMDHDLFGILESKSV-ITDEQVASIFKQLLEGIQYCHSRNFLHRDIKCSNILVNNRGEIKLADFGLARLYIAD---DKKRPYTNKVITLWYRPPELLLGEECYSPAIDIWSLGCILGELFT 559
BLAST of Cyclin-dependent kinase 9 vs. Planmine SMEST
Match: SMESG000057162.1 (SMESG000057162.1) HSP 1 Score: 201.83 bits (512), Expect = 6.515e-57 Identity = 104/214 (48.60%), Postives = 139/214 (64.95%), Query Frame = 1
Query: 112 KHVDQYEKLQKIGQGTFGEVFKVRDIQTKKYYALKRIKLEQEKEGFPITALREIKILQSLNHPNIVCLREICC--SSPTKEKLYKPEFYLLFDLCDHDLAGLLSDQNMKFSLPQRKSIMKQLFTGIFYLHRNNVIHRDLKAANILIEKHGTLKIADFGLARYTIKSPKPDHPPKYTSRVVTMWYRPPEILLNDRHYDKSVDMWGAGCIMAELWT 747
+ V + + K+G+GT+G VFK DIQT + ALK+++LE EKEGFPITA+REIKIL L H NIV L EI + K K FYL+FD DHDL G+L +++ + Q SI KQL GI Y H N +HRD+K +NIL+ G +K+ADFGLAR I D YT++V+T+WYRPPE+LL + Y ++D+W GCI+ EL+T
Sbjct: 356 RSVSAFRFIDKVGEGTYGHVFKAEDIQTGELKALKKVRLENEKEGFPITAIREIKILMQLVHANIVNLCEIVTDIDNALDFKKDKGAFYLVFDYMDHDLFGILESKSV-ITDEQVASIFKQLLEGIQYCHSRNFLHRDIKCSNILVNNRGEIKLADFGLARLYIAD---DKKRPYTNKVITLWYRPPELLLGEECYSPAIDIWSLGCILGELFT 565 The following BLAST results are available for this feature:
BLAST of Cyclin-dependent kinase 9 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Cyclin-dependent kinase 9 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Cyclin-dependent kinase 9 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Cyclin-dependent kinase 9 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Cyclin-dependent kinase 9 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Cyclin-dependent kinase 9 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Cyclin-dependent kinase 9 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Cyclin-dependent kinase 9 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Cyclin-dependent kinase 9 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Cyclin-dependent kinase 9 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of Cyclin-dependent kinase 9 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 5
BLAST of Cyclin-dependent kinase 9 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Cyclin-dependent kinase 9 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Cyclin-dependent kinase 9 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30009003 ID=SMED30009003|Name=Cyclin-dependent kinase 9|organism=Schmidtea mediterranea sexual|type=transcript|length=1292bpback to top protein sequence of SMED30009003-orf-1 >SMED30009003-orf-1 ID=SMED30009003-orf-1|Name=SMED30009003-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=260bp MEDFNKLYSEVINDISFGLQDFFKRIQSDPNLSVLKHVDQYEKLQKIGQGback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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