Fascin

Overview
NameFascin
Smed IDSMED30008911
Length (bp)2164
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Fascin (SMED30008911) t-SNE clustered cells

Violin plots show distribution of expression levels for Fascin (SMED30008911) in cells (dots) of each of the 12 neoblast clusters.

 

back to top

 

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Fascin (SMED30008911) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Fascin (SMED30008911) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

back to top

 

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

back to top
Anatomical Expression

PAGE et. al., 2020



SMED30008911

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 17

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
Smed sexual biotypeSMED30008911h1SMcG0002267 Contig39801newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30008911h1SMcG0002267 Contig39801uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
pharynxSMED30008911h1SMcG0002267 dd_Smed_v4_996_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
protonephridiaSMED30008911h1SMcG0002267 dd_Smed_v4_996_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
nervous systemSMED30008911h1SMcG0002267 dd_Smed_v4_996_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
gutSMED30008911h1SMcG0002267 dd_Smed_v4_996_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30008911h1SMcG0002267 dd_Smed_v4_996_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30008911h1SMcG0002267 dd_Smed_v4_996_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
muscle cellSMED30008911h1SMcG0002267 dd_Smed_v4_996_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parapharyngeal regionSMED30008911h1SMcG0002267 dd_Smed_v4_996_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30008911h1SMcG0002267 dd_Smed_v4_996_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30008911h1SMcG0002267 dd_Smed_v4_996_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cilated neuronSMED30008911h1SMcG0002267 dd_Smed_v4_996_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
whole organismSMED30008911h1SMcG0002267 Contig39801newmark_estsPMID:27612384
Roberts-Galbraith et al., 2016		whole organism asexual adult colorimetric in situ hybridization evidence
whole organismSMED30008911h1SMcG0002267 Contig39801uc_Smed_v2PMID:27612384
Roberts-Galbraith et al., 2016		whole organism asexual adult colorimetric in situ hybridization evidence
progenitor cellSMED30008911h1SMcG0002267 dd_Smed_v6_996_0dd_Smed_v6PMID:29674432
Plass et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30008911h1SMcG0002267 dd_Smed_v6_996_0dd_Smed_v6PMID:29674432
Plass et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Fascin vs. Ensembl Human
Match: FSCN1 (fascin actin-bundling protein 1 [Source:HGNC Symbol;Acc:HGNC:11148])

HSP 1 Score: 350.132 bits (897), Expect = 2.467e-112
Identity = 205/509 (40.28%), Postives = 304/509 (59.72%), Query Frame = 2 
Query:  380 VNGSSESFNPILTWEMGIVNEAGKYLTAETFGFKINVSATSLKKRQLWTM--IPDKT-AEYFFIKSHLNRYLSSDKDGKVSCEVEENGVEEQFFIEYCPKGTGKWAFKSVAYGYYLTGNEDRISCFSKSPSW---WSARLAIHPQVHMQNMKRQRYVRLQG---DELHGDQVIPWGFDSLITLEHSTCGKVAVCSRDHRYLNKDGSLSDKITENSLYGLELRGGANPGFTFKDNEGKYLTLIGSTGTVKS-KNKVVSKDEIFTLEISYPQVGLRAHNGKFASIKQGVDLYANQADAEEKEIFQLEYQNSSKKWKIRTCDGKYWTVTSVNSGIKATSGDNNESSLFDIIHLTSGKVLIKASNNMYVSSKKLGLMSATGENAEDVESLFQAILLNRPMIIFKSDFGLVGIR--NNRVECNMSTYEAFQLETANDGNYMLKVCGNKDAYWRTGDDNGIKIDGSAPPQQFILQFDSGTHCAILASNGKYIRGEQNGLMKADSDEINKASLWEF 1870
             NG++E+    +  + G++N   KYLTAE FGFK+N SA+SLKK+Q+WT+   PD+  +    ++SHL RYL++DKDG V+CE E  G + +F I       G+W+ +S A+  Y  G EDR+SCF+++ S    WS  +A+HPQV++ ++ R+RY  L     DE+  D+ +PWG DSLITL      + +V + DHR+L  DG L  +    + Y LE R G      F+D EG+YL   G +GT+K+ K   V KDE+F LE S  QV L+A N +  S +QG+DL ANQ +  ++E FQLE    +KK   RT  GKYWT+T+   G+++T+   N S  FD I     ++ ++ASN  +V+SKK G ++A+ E A D E LF   L+NRP+I+F+ + G +G R     ++ N S+Y+ FQLE  NDG Y +K    K  YW  G D+ +   G   P  F  +F      AI    G+Y++G+  G++KA ++ ++ ASLWE+
Sbjct:    3 ANGTAEA----VQIQFGLINCGNKYLTAEAFGFKVNASASSLKKKQIWTLEQPPDEAGSAAVCLRSHLGRYLAADKDGNVTCEREVPGPDCRFLI--VAHDDGRWSLQSEAHRRYFGGTEDRLSCFAQTVSPAEKWSVHIAMHPQVNIYSVTRKRYAHLSARPADEIAVDRDVPWGVDSLITLAFQD-QRYSVQTADHRFLRHDGRLVARPEPATGYTLEFRSGK---VAFRDCEGRYLAPSGPSGTLKAGKATKVGKDELFALEQSCAQVVLQAANERNVSTRQGMDLSANQDEETDQETFQLEIDRDTKKCAFRTHTGKYWTLTATG-GVQSTASSKNASCYFD-IEWRDRRITLRASNGKFVTSKKNGQLAASVETAGDSE-LFLMKLINRPIIVFRGEHGFIGCRKVTGTLDANRSSYDVFQLEF-NDGAYNIKDSTGK--YWTVGSDSAVTSSGDT-PVDFFFEFCDYNKVAIKV-GGRYLKGDHAGVLKASAETVDPASLWEY 493
[Close]
BLAST of Fascin vs. Ensembl Human
Match: FSCN2 (fascin actin-bundling protein 2, retinal [Source:HGNC Symbol;Acc:HGNC:3960])

HSP 1 Score: 318.161 bits (814), Expect = 3.804e-100
Identity = 185/512 (36.13%), Postives = 292/512 (57.03%), Query Frame = 2 
Query:  365 MSSNGVNGSSESFNPILTWEMGIVNEAGKYLTAETFGFKINVSATSLKKRQLWTMIPD--KTAEYFFIKSHLNRYLSSDKDGKVSCEVEENGVEEQFFIEYCPKGTGKWAFKSVAYGYYLTGNEDRISCFSKSPS---WWSARLAIHPQVHMQNMKRQRYVRL--QGDELHGDQVIPWGFDSLITLEHSTCGKVAVCSRDHRYLNKDGSLSDKITENSLYGLELRGGANPGFTFKDNEGKYLTLIGSTGTVKS-KNKVVSKDEIFTLEISYPQVGLRAHNGKFASIKQGVDLYANQADAEEKEIFQLEYQNSSKKWKIRTCDGKYWTVTSVNSGIKATSGDNNESSLFDIIHLTSGKVLIKASNNMYVSSKKLGLMSATGENAEDVESLFQAILLNRPMIIFKSDFGLVGIR--NNRVECNMSTYEAFQLETANDGNYMLKVCGNKDAYWRTGDDNGIKIDGSAPPQQFILQFDSGTHCAILASNGKYIRGEQNGLMKADSDEINKASLWEF 1870
            M +NG++        +L  + G+VN+  +YLTAE+FGFK+N SA SLK++Q W + PD  +        SHL RYLS+++DG+V+CE E+ G + +F +   P+  G+W  +S  +G +  G ED++SCF+ + S    W+  LAIHPQ H+ ++ R+RYV L  + DE+  D   PWG D+L+TL   +  +  + S D RYL  DG L  +    + Y LE + G      FKD +G YL  +G  GT+K+ +N    KDE+F LE S+PQV L A N ++ S++QGV++ ANQ D  + E F ++    +KK    +  G YWT+ + + GI AT+   + +++F+ +     +V +KASN  YV  KK G ++A  +     E  F   L+NRP+++ +   G V     +N+++ N S Y+ F L + +DG Y ++  G    +W TG    +  DG    + F+ +F      AI A +GKY+RG  +GL++AD+D     +LWE+
Sbjct:    1 MPTNGLH-------QVLKIQFGLVNDTDRYLTAESFGFKVNASAPSLKRKQTWVLEPDPGQGTAVLLRSSHLGRYLSAEEDGRVACEAEQPGRDCRFLV--LPQPDGRWVLRSEPHGRFFGGTEDQLSCFATAVSPAELWTVHLAIHPQAHLLSVSRRRYVHLCPREDEMAADGDKPWGVDALLTLIFRS-RRYCLKSCDSRYLRSDGRLVWEPEPRACYTLEFKAGK---LAFKDCDGHYLAPVGPAGTLKAGRNTRPGKDELFDLEESHPQVVLVAANHRYVSVRQGVNVSANQDDELDHETFLMQIDQETKKCTFYSSTGGYWTLVT-HGGIHATATQVSANTMFE-MEWRGRRVALKASNGRYVCMKKNGQLAAISDFVGKDEE-FTLKLINRPILVLRGLDGFVCHHRGSNQLDTNRSVYDVFHL-SFSDGAYRIR--GRDGGFWYTGSHGSVCSDGER-AEDFVFEFRERGRLAIRARSGKYLRGGASGLLRADADAPAGTALWEY 492
[Close]
BLAST of Fascin vs. Ensembl Human
Match: FSCN2 (fascin actin-bundling protein 2, retinal [Source:HGNC Symbol;Acc:HGNC:3960])

HSP 1 Score: 310.457 bits (794), Expect = 6.725e-97
Identity = 188/535 (35.14%), Postives = 295/535 (55.14%), Query Frame = 2 
Query:  365 MSSNGVNGSSESFNPILTWEMGIVNEAGKYLTAETFGFKINVSATSLKKRQLWTMIPD--KTAEYFFIKSHLNRYLSSDKDGKVSCEVEENGVEEQFFIEYCPKGTGKWAFKSVAYGYYLTGNEDRISCFSK--SPS-WWSARLAIHPQVHMQNMKRQRYVRL--QGDELHGDQVIPWGFDSLITLEHSTCGKVAVCSRDHRYLNKDGSLSDKITENSLYGLELRGGANPGFTFKDNEGKYLTLIGSTGTVKS-KNKVVSKDEIFTLEISYPQVGLRAHNGKFASIKQGVDLYANQADAEEKEIFQLEYQNSSKKWKIRTCDGKYWTVTSVNSGIKATSGDNNESSLFDIIHLTSGKVLIKASNNMYVSSKKLGLMSA-----------------TGENAEDVESL------FQAILLNRPMIIFKSDFGLVGIR--NNRVECNMSTYEAFQLETANDGNYMLKVCGNKDAYWRTGDDNGIKIDGSAPPQQFILQFDSGTHCAILASNGKYIRGEQNGLMKADSDEINKASLWEF 1870
            M +NG++        +L  + G+VN+  +YLTAE+FGFK+N SA SLK++Q W + PD  +        SHL RYLS+++DG+V+CE E+ G + +F +   P+  G+W  +S  +G +  G ED++SCF+   SP+  W+  LAIHPQ H+ ++ R+RYV L  + DE+  D   PWG D+L+TL   +  +  + S D RYL  DG L  +    + Y LE + G      FKD +G YL  +G  GT+K+ +N    KDE+F LE S+PQV L A N ++ S++QGV++ ANQ D  + E F ++    +KK    +  G YWT+ + + GI AT+   + +++F+ +     +V +KASN  YV  KK G ++A                  G  A+   S       F   L+NRP+++ +   G V     +N+++ N S Y+ F L + +DG Y ++  G    +W TG    +  DG    + F+ +F      AI A +GKY+RG  +GL++AD+D     +LWE+
Sbjct:    1 MPTNGLH-------QVLKIQFGLVNDTDRYLTAESFGFKVNASAPSLKRKQTWVLEPDPGQGTAVLLRSSHLGRYLSAEEDGRVACEAEQPGRDCRFLV--LPQPDGRWVLRSEPHGRFFGGTEDQLSCFATAVSPAELWTVHLAIHPQAHLLSVSRRRYVHLCPREDEMAADGDKPWGVDALLTLIFRS-RRYCLKSCDSRYLRSDGRLVWEPEPRACYTLEFKAGK---LAFKDCDGHYLAPVGPAGTLKAGRNTRPGKDELFDLEESHPQVVLVAANHRYVSVRQGVNVSANQDDELDHETFLMQIDQETKKCTFYSSTGGYWTLVT-HGGIHATATQVSANTMFE-MEWRGRRVALKASNGRYVCMKKNGQLAAISDFVGPPPRPAWTGKVAGGAAQQTLSPPGKDEEFTLKLINRPILVLRGLDGFVCHHRGSNQLDTNRSVYDVFHL-SFSDGAYRIR--GRDGGFWYTGSHGSVCSDGER-AEDFVFEFRERGRLAIRARSGKYLRGGASGLLRADADAPAGTALWEY 516
[Close]
BLAST of Fascin vs. Ensembl Human
Match: FSCN3 (fascin actin-bundling protein 3 [Source:HGNC Symbol;Acc:HGNC:3961])

HSP 1 Score: 122.094 bits (305), Expect = 1.279e-28
Identity = 113/499 (22.65%), Postives = 201/499 (40.28%), Query Frame = 2 
Query:  422 EMGIVNEAGKYLTAETFGFKINVSATSLKKRQLWTMI---PDKTAEYFFIKSHLNRYLSSDKDGKVSCEVEENGVEEQFFIEYCPKGTGKWAFKSVAYGYYLTGNEDRISCFSKSPS---WWSARLAIHPQVHMQNMKRQRYVRLQGDELHG----DQVIPWGFDSLITLEHSTCGKVAVCSRDHRYLNKDGSLSDKITENSLYGLELRGGANPGFTFKDNEGKYLTLIGSTGTVKSKNKVVSKDEIFTLEISYPQVGLRAHNGKFASIKQGVDLYANQADAEEKEIFQLEYQNSSKKWKIRTCDGKYWTVTSVNSGIKATSGDNNESSLFDIIHLTSGKVLIKASNNMYVSSKKLGLMSA----TGENAEDVESLFQAILLNRPMIIFKSDFGLVGIR--NNRVECNMSTYEAFQLETANDGNYMLKVCGNKDAYWRTGDDNGIKIDGSAPPQQFILQFDSGTHCAILASNGKYIRGEQNGLMKADSDEINKASLWEF 1870
             +G+++ AG YLT E     +  +A SL +RQ W ++     +T     +KS    YL  + DG V            F + +      KW  + +  G YL  N   + C S   S    W+ R A+H  V + +   + Y R   D   G    D  +P   +    L H   G   + +  H +L+    L  + +  + + +++R G        D EG  L   G+   +      +  +E F L+     V LR+  G+F S+    ++ A         +FQ E  + S   ++R+ +G Y  ++          G   ES  F  +H   G++++++    ++      L+ A     G N E     F  +  NR  ++ +  +G VG    ++ ++CN    +   L     G Y  +  G   ++W        +  G      F ++        +LA NG Y+R +Q+G + ADS++I +  +WEF
Sbjct:   17 RVGLISWAGTYLTFEACKNTVTATAKSLGRRQTWEILVSNEHETQAVVRLKSVQGLYLLCECDGTVCYGRPRTSHHGCFLLRF--HRNSKWTLQCLISGRYLESNGKDVFCTSHVLSAYHMWTPRPALHVHVILYSPIHRCYAR--ADPTMGRIWVDAAVP-CLEECGFLLHFRDGCYHLETSTHHFLSHVDRLFSQPSSQTAFHMQVRPGGLVALC--DGEGGMLYPQGTHLLLGMGCNPMRGEEWFILQHCPTWVSLRSKTGRFISVIYDGEVRAASERLNRMSLFQFECDSESPTVQLRSANGYY--LSQRRHRAVMADGHPLESDTFFRMHWNCGRIILQSCRGRFLGIAPNSLLMANVILPGPNEE-----FGILFANRSFLVLRGRYGYVGSSSGHDLIQCNQDQPDRIHLLPCRPGIYHFQAQGG--SFWSITSFGTFRPWGKFA-LNFCIELQGSNLLTVLAPNGFYMRADQSGTLLADSEDITRECIWEF 498
[Close]
BLAST of Fascin vs. Ensembl Human
Match: FSCN1 (fascin actin-bundling protein 1 [Source:HGNC Symbol;Acc:HGNC:11148])

HSP 1 Score: 100.908 bits (250), Expect = 2.290e-24
Identity = 56/140 (40.00%), Postives = 86/140 (61.43%), Query Frame = 2 
Query: 1208 VDLYANQADAEEKEIFQLEYQNSSKKWKIRTCDGKYWTVTSVNSGIKATSGDNNESSLFDIIHLTSGKVLIKASNNMYVSSKKLGLMSATGENAEDVESLFQAILLNRPMIIFKSDFGLVGIR--NNRVECNMSTYEAFQ 1621
            +DL ANQ +  ++E FQLE    +KK   RT  GKYWT+T+   G+++T+   N S  FD I     ++ ++ASN  +V+SKK G ++A+ E A D E LF   L+NRP+I+F+ + G +G R     ++ N S+Y+ FQ
Sbjct:    1 MDLSANQDEETDQETFQLEIDRDTKKCAFRTHTGKYWTLTATG-GVQSTASSKNASCYFD-IEWRDRRITLRASNGKFVTSKKNGQLAASVETAGDSE-LFLMKLINRPIIVFRGEHGFIGCRKVTGTLDANRSSYDVFQ 137
[Close]
BLAST of Fascin vs. Ensembl Fly
Match: sn (gene:FBgn0003447 transcript:FBtr0301679)

HSP 1 Score: 347.821 bits (891), Expect = 1.739e-111
Identity = 191/496 (38.51%), Postives = 290/496 (58.47%), Query Frame = 2 
Query:  419 WEMGIVNEAGKYLTAETFGFKINVSATSLKKRQLWTMIPDKTAE-YFFIKSHLNRYLSSDKDGKVSCEVEENGVEEQFFIEYCPKGTGKWAFKSVAYGYYLTGNEDRISCFSKSP---SWWSARLAIHPQVHMQNMKRQRYVRL--QGDELHGDQVIPWGFDSLITLEHST--CGKVAVCSRDHRYLNKDGSLSDKITENSLYGLELRGGANPGFTFKDNEGKYLTLIGSTGTVKSKNKVVSKDEIFTLEISYPQVGLRAH-NGKFASIKQGVDLYANQADAEEKEIFQLEYQNSSKKWKIRTCDGKYWTVTSVNSGIKATSGDNNESSLFDIIHLTSGKVLIKASNNMYVSSKKLGLMSATGENAEDVESLFQAILLNRPMIIFKSDFGLVGIR---NNRVECNMSTYEAFQLETANDGNYMLKVCGNKDAYWRTGDDNGIKIDGSAPPQQFILQFDSGTHCAILASNGKYIRGEQNGLMKADSDEINKASLWEF 1870
            W +G++N   KY+TAETFGFK+N +  SLKK+QLWT+ P  T E   +++SHLN+YLS D+ G V CE +E     +F I     G+G+WA K+ + GY+L G  D++ C +K+P    +W+  LA  PQV+++++ R+R+  L    DE+H D  IPWG D+L TLE      G+ A+ + +++YLN +G L     E+ L+  E  GG       +D +G+YL+ IGS   +KS++  V++DE+F+LE S PQ    A  N ++ S+KQGVD+ ANQ +  E E FQLEY  S+ +W +RT   +YW + S   GI+AT       +LF++I    G +  +A+N  ++++K+ G + AT E+ E++ + F   L+NRP+++ K + G VG R   N ++ECN +TYE   +E A  G   LK    K  YWR  +   I +D  AP   F L+    T   I +  GKY+   +NG  K   D  + A+ WEF
Sbjct:   25 WTIGLINGQHKYMTAETFGFKLNANGASLKKKQLWTLEPSNTGESIIYLRSHLNKYLSVDQFGNVLCESDERDAGSRFQISISEDGSGRWALKNESRGYFLGGTPDKLVCTAKTPGASEFWTVHLAARPQVNLRSIGRKRFAHLSESQDEIHVDANIPWGEDTLFTLEFRAEEGGRYALHTCNNKYLNANGKLQVVCNEDCLFSAEYHGGH---LALRDRQGQYLSPIGSKAVLKSRSSSVTRDELFSLEDSLPQASFIAGLNLRYVSVKQGVDVTANQDEVGENETFQLEYDWSAHRWALRTTQDRYWCL-SAGGGIQATGNRRCADALFELIWHGDGSLSFRANNGKFLATKRSGHLFATSESIEEI-AKFYFYLINRPILVLKCEQGFVGYRTPGNLKLECNKATYETILVERAQKGLVHLKAHSGK--YWRI-EGESISVDADAPSDGFFLELREPTRICIRSQQGKYLGATKNGAFKLLDDGTDSATQWEF 512
[Close]
BLAST of Fascin vs. Ensembl Fly
Match: sn (gene:FBgn0003447 transcript:FBtr0301677)

HSP 1 Score: 347.821 bits (891), Expect = 1.739e-111
Identity = 191/496 (38.51%), Postives = 290/496 (58.47%), Query Frame = 2 
Query:  419 WEMGIVNEAGKYLTAETFGFKINVSATSLKKRQLWTMIPDKTAE-YFFIKSHLNRYLSSDKDGKVSCEVEENGVEEQFFIEYCPKGTGKWAFKSVAYGYYLTGNEDRISCFSKSP---SWWSARLAIHPQVHMQNMKRQRYVRL--QGDELHGDQVIPWGFDSLITLEHST--CGKVAVCSRDHRYLNKDGSLSDKITENSLYGLELRGGANPGFTFKDNEGKYLTLIGSTGTVKSKNKVVSKDEIFTLEISYPQVGLRAH-NGKFASIKQGVDLYANQADAEEKEIFQLEYQNSSKKWKIRTCDGKYWTVTSVNSGIKATSGDNNESSLFDIIHLTSGKVLIKASNNMYVSSKKLGLMSATGENAEDVESLFQAILLNRPMIIFKSDFGLVGIR---NNRVECNMSTYEAFQLETANDGNYMLKVCGNKDAYWRTGDDNGIKIDGSAPPQQFILQFDSGTHCAILASNGKYIRGEQNGLMKADSDEINKASLWEF 1870
            W +G++N   KY+TAETFGFK+N +  SLKK+QLWT+ P  T E   +++SHLN+YLS D+ G V CE +E     +F I     G+G+WA K+ + GY+L G  D++ C +K+P    +W+  LA  PQV+++++ R+R+  L    DE+H D  IPWG D+L TLE      G+ A+ + +++YLN +G L     E+ L+  E  GG       +D +G+YL+ IGS   +KS++  V++DE+F+LE S PQ    A  N ++ S+KQGVD+ ANQ +  E E FQLEY  S+ +W +RT   +YW + S   GI+AT       +LF++I    G +  +A+N  ++++K+ G + AT E+ E++ + F   L+NRP+++ K + G VG R   N ++ECN +TYE   +E A  G   LK    K  YWR  +   I +D  AP   F L+    T   I +  GKY+   +NG  K   D  + A+ WEF
Sbjct:   25 WTIGLINGQHKYMTAETFGFKLNANGASLKKKQLWTLEPSNTGESIIYLRSHLNKYLSVDQFGNVLCESDERDAGSRFQISISEDGSGRWALKNESRGYFLGGTPDKLVCTAKTPGASEFWTVHLAARPQVNLRSIGRKRFAHLSESQDEIHVDANIPWGEDTLFTLEFRAEEGGRYALHTCNNKYLNANGKLQVVCNEDCLFSAEYHGGH---LALRDRQGQYLSPIGSKAVLKSRSSSVTRDELFSLEDSLPQASFIAGLNLRYVSVKQGVDVTANQDEVGENETFQLEYDWSAHRWALRTTQDRYWCL-SAGGGIQATGNRRCADALFELIWHGDGSLSFRANNGKFLATKRSGHLFATSESIEEI-AKFYFYLINRPILVLKCEQGFVGYRTPGNLKLECNKATYETILVERAQKGLVHLKAHSGK--YWRI-EGESISVDADAPSDGFFLELREPTRICIRSQQGKYLGATKNGAFKLLDDGTDSATQWEF 512
[Close]
BLAST of Fascin vs. Ensembl Fly
Match: sn (gene:FBgn0003447 transcript:FBtr0071101)

HSP 1 Score: 347.821 bits (891), Expect = 1.739e-111
Identity = 191/496 (38.51%), Postives = 290/496 (58.47%), Query Frame = 2 
Query:  419 WEMGIVNEAGKYLTAETFGFKINVSATSLKKRQLWTMIPDKTAE-YFFIKSHLNRYLSSDKDGKVSCEVEENGVEEQFFIEYCPKGTGKWAFKSVAYGYYLTGNEDRISCFSKSP---SWWSARLAIHPQVHMQNMKRQRYVRL--QGDELHGDQVIPWGFDSLITLEHST--CGKVAVCSRDHRYLNKDGSLSDKITENSLYGLELRGGANPGFTFKDNEGKYLTLIGSTGTVKSKNKVVSKDEIFTLEISYPQVGLRAH-NGKFASIKQGVDLYANQADAEEKEIFQLEYQNSSKKWKIRTCDGKYWTVTSVNSGIKATSGDNNESSLFDIIHLTSGKVLIKASNNMYVSSKKLGLMSATGENAEDVESLFQAILLNRPMIIFKSDFGLVGIR---NNRVECNMSTYEAFQLETANDGNYMLKVCGNKDAYWRTGDDNGIKIDGSAPPQQFILQFDSGTHCAILASNGKYIRGEQNGLMKADSDEINKASLWEF 1870
            W +G++N   KY+TAETFGFK+N +  SLKK+QLWT+ P  T E   +++SHLN+YLS D+ G V CE +E     +F I     G+G+WA K+ + GY+L G  D++ C +K+P    +W+  LA  PQV+++++ R+R+  L    DE+H D  IPWG D+L TLE      G+ A+ + +++YLN +G L     E+ L+  E  GG       +D +G+YL+ IGS   +KS++  V++DE+F+LE S PQ    A  N ++ S+KQGVD+ ANQ +  E E FQLEY  S+ +W +RT   +YW + S   GI+AT       +LF++I    G +  +A+N  ++++K+ G + AT E+ E++ + F   L+NRP+++ K + G VG R   N ++ECN +TYE   +E A  G   LK    K  YWR  +   I +D  AP   F L+    T   I +  GKY+   +NG  K   D  + A+ WEF
Sbjct:   25 WTIGLINGQHKYMTAETFGFKLNANGASLKKKQLWTLEPSNTGESIIYLRSHLNKYLSVDQFGNVLCESDERDAGSRFQISISEDGSGRWALKNESRGYFLGGTPDKLVCTAKTPGASEFWTVHLAARPQVNLRSIGRKRFAHLSESQDEIHVDANIPWGEDTLFTLEFRAEEGGRYALHTCNNKYLNANGKLQVVCNEDCLFSAEYHGGH---LALRDRQGQYLSPIGSKAVLKSRSSSVTRDELFSLEDSLPQASFIAGLNLRYVSVKQGVDVTANQDEVGENETFQLEYDWSAHRWALRTTQDRYWCL-SAGGGIQATGNRRCADALFELIWHGDGSLSFRANNGKFLATKRSGHLFATSESIEEI-AKFYFYLINRPILVLKCEQGFVGYRTPGNLKLECNKATYETILVERAQKGLVHLKAHSGK--YWRI-EGESISVDADAPSDGFFLELREPTRICIRSQQGKYLGATKNGAFKLLDDGTDSATQWEF 512
[Close]
BLAST of Fascin vs. Ensembl Fly
Match: sn (gene:FBgn0003447 transcript:FBtr0071102)

HSP 1 Score: 347.821 bits (891), Expect = 1.739e-111
Identity = 191/496 (38.51%), Postives = 290/496 (58.47%), Query Frame = 2 
Query:  419 WEMGIVNEAGKYLTAETFGFKINVSATSLKKRQLWTMIPDKTAE-YFFIKSHLNRYLSSDKDGKVSCEVEENGVEEQFFIEYCPKGTGKWAFKSVAYGYYLTGNEDRISCFSKSP---SWWSARLAIHPQVHMQNMKRQRYVRL--QGDELHGDQVIPWGFDSLITLEHST--CGKVAVCSRDHRYLNKDGSLSDKITENSLYGLELRGGANPGFTFKDNEGKYLTLIGSTGTVKSKNKVVSKDEIFTLEISYPQVGLRAH-NGKFASIKQGVDLYANQADAEEKEIFQLEYQNSSKKWKIRTCDGKYWTVTSVNSGIKATSGDNNESSLFDIIHLTSGKVLIKASNNMYVSSKKLGLMSATGENAEDVESLFQAILLNRPMIIFKSDFGLVGIR---NNRVECNMSTYEAFQLETANDGNYMLKVCGNKDAYWRTGDDNGIKIDGSAPPQQFILQFDSGTHCAILASNGKYIRGEQNGLMKADSDEINKASLWEF 1870
            W +G++N   KY+TAETFGFK+N +  SLKK+QLWT+ P  T E   +++SHLN+YLS D+ G V CE +E     +F I     G+G+WA K+ + GY+L G  D++ C +K+P    +W+  LA  PQV+++++ R+R+  L    DE+H D  IPWG D+L TLE      G+ A+ + +++YLN +G L     E+ L+  E  GG       +D +G+YL+ IGS   +KS++  V++DE+F+LE S PQ    A  N ++ S+KQGVD+ ANQ +  E E FQLEY  S+ +W +RT   +YW + S   GI+AT       +LF++I    G +  +A+N  ++++K+ G + AT E+ E++ + F   L+NRP+++ K + G VG R   N ++ECN +TYE   +E A  G   LK    K  YWR  +   I +D  AP   F L+    T   I +  GKY+   +NG  K   D  + A+ WEF
Sbjct:   25 WTIGLINGQHKYMTAETFGFKLNANGASLKKKQLWTLEPSNTGESIIYLRSHLNKYLSVDQFGNVLCESDERDAGSRFQISISEDGSGRWALKNESRGYFLGGTPDKLVCTAKTPGASEFWTVHLAARPQVNLRSIGRKRFAHLSESQDEIHVDANIPWGEDTLFTLEFRAEEGGRYALHTCNNKYLNANGKLQVVCNEDCLFSAEYHGGH---LALRDRQGQYLSPIGSKAVLKSRSSSVTRDELFSLEDSLPQASFIAGLNLRYVSVKQGVDVTANQDEVGENETFQLEYDWSAHRWALRTTQDRYWCL-SAGGGIQATGNRRCADALFELIWHGDGSLSFRANNGKFLATKRSGHLFATSESIEEI-AKFYFYLINRPILVLKCEQGFVGYRTPGNLKLECNKATYETILVERAQKGLVHLKAHSGK--YWRI-EGESISVDADAPSDGFFLELREPTRICIRSQQGKYLGATKNGAFKLLDDGTDSATQWEF 512
[Close]
BLAST of Fascin vs. Ensembl Zebrafish
Match: fscn1a (fascin actin-bundling protein 1a [Source:ZFIN;Acc:ZDB-GENE-031009-1])

HSP 1 Score: 354.369 bits (908), Expect = 2.924e-114
Identity = 202/506 (39.92%), Postives = 312/506 (61.66%), Query Frame = 2 
Query:  380 VNGSSESFNPILTWEMGIVNEAGKYLTAETFGFKINVSATSLKKRQLWTMIPD-KTAEYFFIKSHLNRYLSSDKDGKVSCEVEENGVEEQFFIEYCPKGTGKWAFKSVAYGYYLTGNEDRISCFSKSPSW---WSARLAIHPQVHMQNMKRQRYVRL--QGDELHGDQVIPWGFDSLITLEHSTCGKVAVCSRDHRYLNKDGSLSDKITENSLYGLELRGGANPGFTFKDNEGKYLTLIGSTGTVKS-KNKVVSKDEIFTLEISYPQVGLRAHNGKFASIKQGVDLYANQADAEEKEIFQLEYQNSSKKWKIRTCDGKYWTVTSVNSGIKATSGDNNESSLFDIIHLTSGKVLIKASNNMYVSSKKLGLMSATGENAEDVESLFQAILLNRPMIIFKSDFGLVGIR--NNRVECNMSTYEAFQLETANDGNYMLKVCGNKDAYWRTGDDNGIKIDGSAPPQQFILQFDSGTHCAILASNGKYIRGEQNGLMKADSDEINKASLWEF 1870
             NG+S+    +L  + G++N   KYLTAETFGFKIN SATS+KK+Q+WT+  D   +  FF+KSHL RY+++DKDG V+ + E  G + +F I       G+W+ +S  +  YL G EDRI+CF+++ S    WS  +A+HPQV++ ++ R+RY  L  + +E+  D+ +PWG DSLITL      +  + + D+R+L  DGSLS    + + Y LE R G      F+D  GKYL   G +GT+KS K+  V KDE+F LE S+PQV L A N +  S +QG+DL ANQ +  ++E FQ+E    +KK   RTC GKYWT+T+ N G++ T+   + +  FD I     K+ ++A+N  YV++KK G ++AT ++A + E  F   L+NRP+I+ + + G +G R     ++ N S+Y+ F L+  NDG Y L+ C  K  YW  G ++ + +  S  P  F L+F      AI  + GKY++G+  G++KA++D+++ +++WE+
Sbjct:    3 ANGTSD----MLKIQFGLINCGNKYLTAETFGFKINASATSMKKKQIWTLEQDGDDSNMFFLKSHLGRYIAADKDGNVTGDSETPGEDCRFII--TAHDDGRWSLQSEPHKRYLGGTEDRITCFAQTISIAEKWSVHIAMHPQVNIFSVTRKRYAHLSSEQNEIAIDRDVPWGVDSLITLVFQD-QRYHLQTSDNRFLKNDGSLSQTADKTTGYTLEFRSGK---VAFRDCTGKYLAPSGPSGTMKSGKSMKVGKDELFVLEQSHPQVVLTAGNDRNVSTRQGMDLSANQDEEGDQETFQMEISKDTKKCAFRTCTGKYWTLTA-NGGLQCTASTKSANCYFD-IEWRGKKITLRATNGKYVAAKKNGQLAATIDSAGETEE-FLMKLINRPLIVLRGEHGFIGCRRVTGTLDSNRSSYDVFGLD-FNDGAYSLRDCTGK--YWMVGSESNV-LSSSDTPVDFFLEFCDYNKVAIKTTEGKYLKGDHAGVLKANADDLDSSTMWEY 491
[Close]
BLAST of Fascin vs. Ensembl Zebrafish
Match: fscn2b (fascin actin-bundling protein 2b, retinal [Source:ZFIN;Acc:ZDB-GENE-040426-1740])

HSP 1 Score: 337.035 bits (863), Expect = 1.559e-107
Identity = 195/495 (39.39%), Postives = 296/495 (59.80%), Query Frame = 2 
Query:  413 LTWEMGIVNEAGKYLTAETFGFKINVSATSLKKRQLWTM-IPDKTAEYFFIKSHLNRYLSSDKDGKVSCEVEENGVEEQFFIEYCPKGTGKWAFKSVAYGYYLTGNEDRISCFSKS---PSWWSARLAIHPQVHMQNMKRQRYVRLQGDE--LHGDQVIPWGFDSLITLEHSTCGKVAVCSRDHRYLNKDGSLSDKITENSLYGLELRGGANPGFTFKDNEGKYLTLIGSTGTVKS-KNKVVSKDEIFTLEISYPQVGLRAHNGKFASIKQGVDLYANQADAEEKEIFQLEYQNSSKKWKIRTCDGKYWTVTSVNSGIKATSGDNNESSLFDIIHLTSGKVLIKASNNMYVSSKKLGLMSATGENAEDVESLFQAILLNRPMIIFKSDFGLVGIR--NNRVECNMSTYEAFQLETANDGNYMLKVCGNKDAYWRTGDDNGIKIDGSAPPQQFILQFDSGTHCAILASNGKYIRGEQNGLMKADSDEINKASLWEF 1870
            L  + G++N   +YLTAE FGFK+N SA SLKK+Q+WT+   D+  +  +++SHL RYL+SDKDGKVSCE E    + +F I    +  G+WA +S  Y  +  G+ED +SCF+++      W+  LA+HPQ ++ ++ R+RY  L   E  +  D  IPWG D+L+TL +   GK  + + D R+L+ DG LS +    + Y LEL+ G      FKD EGKYLT +G TGT++S +     KDE+F LE S+PQV  +A N +F SI+QGV + ANQ D  + E FQ+E    ++K K RT +G YWT+ + + GI++T+ +   +++FDI+ L   +V ++ASN  YV +KK G +SA  ++  + E L    L+NRP++I + + G V     +N ++ + S Y+ F L+ + DG Y +K  G K  +W       +  DG   P+ F  +F      AI   NGKY+RG+Q G +K D +  + +SLWE+
Sbjct:    9 LKLQFGLINHENRYLTAEAFGFKVNASAPSLKKKQIWTLEQDDQDGQVVYLRSHLGRYLASDKDGKVSCEAETKENDCRFLI--VAQSDGRWALQSEPYLRFFGGSEDYLSCFAQTIGEAELWAMHLALHPQANLLSVARKRYAHLASPEGEIAVDCNIPWGVDALLTLVYMD-GKYCLKTSDSRFLSNDGKLSSENGRGTGYTLELKSGK---LAFKDCEGKYLTPMGPTGTLRSGRCSKPGKDELFDLEESHPQVVFQAANNRFVSIRQGVSVSANQDDETDMETFQMEIDKDTRKCKFRTNEGNYWTLVA-HGGIQSTATEAGANTMFDIVWLGR-RVALRASNGKYVCTKKNGQLSAVSDSVGEDEQLILK-LINRPILILRGENGYVCHHKNSNTLDASRSVYDIFTLQFS-DGAYHIKGAGGK--FWYVSSSGLVCSDGDT-PEDFSFEFLEHGRIAIRGKNGKYLRGDQGGNLKGDGETADSSSLWEY 490
[Close]
BLAST of Fascin vs. Ensembl Zebrafish
Match: fscn1b (fascin actin-bundling protein 1b [Source:ZFIN;Acc:ZDB-GENE-120507-1])

HSP 1 Score: 331.257 bits (848), Expect = 2.738e-105
Identity = 195/508 (38.39%), Postives = 302/508 (59.45%), Query Frame = 2 
Query:  389 SSESFNPILTWEMGIVNEAGKYLTAETFGFKINVSATSLKKRQLWTMIPDKTAEY-----FFIKSHLNRYLSSDKDGKVSCEVEENGVEEQFFIEYCPKGTGKWAFKSVAYGYYLTGNEDRISCFSKSPSW---WSARLAIHPQVHMQNMKRQRYVRLQGD--ELHGDQVIPWGFDSLITLEHSTCGKVAVCSRDHRYLNKDGSLSDKITENSLYGLELRGGANPGFTFKDNEGKYLTLIGSTGTVKS-KNKVVSKDEIFTLEISYPQVGLRAHNGKFASIKQGVDLYANQADAEEKEIFQLEYQNSSKKWKIRTCDGKYWTVTSVNSGIKATSGDNNESSLFDIIHLTSGKVLIKASNNMYVSSKKLGLMSATGENAEDVESLFQAILLNRPMIIFKSDFGLVGIRNN---RVECNMSTYEAFQLETANDGNYMLKVCGNKDAYWRTGDDNGIKIDGSAPPQQFILQFDSGTHCAILASNGKYIRGEQNGLMKADSDEINKASLWEF 1870
            SSE     L    G++N   KYLTAE FGFKIN SA+S+KK+Q+WT+  +++ ++      FIKSHL RYL+SDKDGKV+ + E+ G + +F +       G+W+ +S  +  YL G EDRI+CF++S S    W+  LA+HPQV++ ++ R+RY  L  D  EL  D+ +PWG DSL+TL +    +  + + D+R+L+  G+L+ K   ++ + LE R G      F+D  GKY+   G TGT+KS ++  V KDE+F LE S+ QV L A N +  S++QGVDL ANQ +  ++E+FQ+E    SK+   R+ +G+YW++TS +  I+ ++   + S  FD +     KV +KASN  Y+++KK G ++A  ++A + E  F   L+NRP+I+ + + G +G R      ++ N S+Y+ FQLE  N+   +    G    YW T + +G  I   A P  F  +F      AI    GKY++G+  G++KA +  I  A+LWE+
Sbjct:    2 SSEGIGETLVIRFGLINADNKYLTAEMFGFKINASASSMKKKQVWTL--EQSGDHGDSNAVFIKSHLGRYLASDKDGKVTADSEQPGPDCRFLV--IAHDDGRWSLQSEPHARYLGGTEDRIACFAQSISPAEKWNVHLAVHPQVNVYSIARKRYAHLCADRNELAVDRDVPWGVDSLLTLVYLD-HRYHLQTADNRFLSCGGTLTAKPDRDTGFTLEFRAGK---VAFRDATGKYIAPTGPTGTMKSGRSARVGKDELFVLEQSHGQVVLTASNDRNISMRQGVDLSANQDEESDQEVFQMEMDRESKRCAFRSFNGRYWSLTS-SGAIQCSALTKSPSCFFD-LEWKGSKVALKASNGKYLAAKKNGQLAAAVDSAGEQEE-FVLKLINRPLIVLRGEHGFIGCRKQGTGTLDSNRSSYDVFQLEYNNNAYSLRDSVGK---YW-TVESDGSVISSGAAPVYFHFEFCDFNKVAIKTKEGKYLKGDHAGVLKASAQGIADATLWEY 494
[Close]
BLAST of Fascin vs. Ensembl Zebrafish
Match: fscn1b (fascin actin-bundling protein 1b [Source:ZFIN;Acc:ZDB-GENE-120507-1])

HSP 1 Score: 331.257 bits (848), Expect = 2.738e-105
Identity = 195/508 (38.39%), Postives = 302/508 (59.45%), Query Frame = 2 
Query:  389 SSESFNPILTWEMGIVNEAGKYLTAETFGFKINVSATSLKKRQLWTMIPDKTAEY-----FFIKSHLNRYLSSDKDGKVSCEVEENGVEEQFFIEYCPKGTGKWAFKSVAYGYYLTGNEDRISCFSKSPSW---WSARLAIHPQVHMQNMKRQRYVRLQGD--ELHGDQVIPWGFDSLITLEHSTCGKVAVCSRDHRYLNKDGSLSDKITENSLYGLELRGGANPGFTFKDNEGKYLTLIGSTGTVKS-KNKVVSKDEIFTLEISYPQVGLRAHNGKFASIKQGVDLYANQADAEEKEIFQLEYQNSSKKWKIRTCDGKYWTVTSVNSGIKATSGDNNESSLFDIIHLTSGKVLIKASNNMYVSSKKLGLMSATGENAEDVESLFQAILLNRPMIIFKSDFGLVGIRNN---RVECNMSTYEAFQLETANDGNYMLKVCGNKDAYWRTGDDNGIKIDGSAPPQQFILQFDSGTHCAILASNGKYIRGEQNGLMKADSDEINKASLWEF 1870
            SSE     L    G++N   KYLTAE FGFKIN SA+S+KK+Q+WT+  +++ ++      FIKSHL RYL+SDKDGKV+ + E+ G + +F +       G+W+ +S  +  YL G EDRI+CF++S S    W+  LA+HPQV++ ++ R+RY  L  D  EL  D+ +PWG DSL+TL +    +  + + D+R+L+  G+L+ K   ++ + LE R G      F+D  GKY+   G TGT+KS ++  V KDE+F LE S+ QV L A N +  S++QGVDL ANQ +  ++E+FQ+E    SK+   R+ +G+YW++TS +  I+ ++   + S  FD +     KV +KASN  Y+++KK G ++A  ++A + E  F   L+NRP+I+ + + G +G R      ++ N S+Y+ FQLE  N+   +    G    YW T + +G  I   A P  F  +F      AI    GKY++G+  G++KA +  I  A+LWE+
Sbjct:    2 SSEGIGETLVIRFGLINADNKYLTAEMFGFKINASASSMKKKQVWTL--EQSGDHGDSNAVFIKSHLGRYLASDKDGKVTADSEQPGPDCRFLV--IAHDDGRWSLQSEPHARYLGGTEDRIACFAQSISPAEKWNVHLAVHPQVNVYSIARKRYAHLCADRNELAVDRDVPWGVDSLLTLVYLD-HRYHLQTADNRFLSCGGTLTAKPDRDTGFTLEFRAGK---VAFRDATGKYIAPTGPTGTMKSGRSARVGKDELFVLEQSHGQVVLTASNDRNISMRQGVDLSANQDEESDQEVFQMEMDRESKRCAFRSFNGRYWSLTS-SGAIQCSALTKSPSCFFD-LEWKGSKVALKASNGKYLAAKKNGQLAAAVDSAGEQEE-FVLKLINRPLIVLRGEHGFIGCRKQGTGTLDSNRSSYDVFQLEYNNNAYSLRDSVGK---YW-TVESDGSVISSGAAPVYFHFEFCDFNKVAIKTKEGKYLKGDHAGVLKASAQGIADATLWEY 494
[Close]
BLAST of Fascin vs. Ensembl Zebrafish
Match: fscn2a (fascin actin-bundling protein 2a, retinal [Source:ZFIN;Acc:ZDB-GENE-110901-1])

HSP 1 Score: 320.857 bits (821), Expect = 2.240e-101
Identity = 198/509 (38.90%), Postives = 295/509 (57.96%), Query Frame = 2 
Query:  365 MSSNGVNGSSESFNPILTWEMGIVNEAGKYLTAETFGFKINVSATSLKKRQLWTMIPDKTAEYFFIKSHLNRYLSSDKDGKVSCEVEENGVEEQFFIEYCPKGTGKWAFKSVAYGYYLTGNEDRISCFSKS---PSWWSARLAIHPQVHMQNMKRQRYVRL--QGDELHGDQVIPWGFDSLITLEHSTCGKVAVCSRDHRYLNKDGSLSDKITENSLYGLELRGGANPGFTFKDNEGKYLTLIGSTGTVKS-KNKVVSKDEIFTLEISYPQVGLRAHNGKFASIKQGVDLYANQADAEEKEIFQLEYQNSSKKWKIRTCDGKYWTVTSVNSGIKATSGDNNESSLFDIIHLTSGKVLIKASNNMYVSSKKLGLMSATGENAEDVESLFQAILLNRPMIIFKSDFGLVGIR--NNRVECNMSTYEAFQLETANDGNYMLKVCGNKDAYWRTGDDNGIKIDGSAPPQQFILQFDSGTHCAILASNGKYIRGEQNGLMKADSDEINKASLWE 1867
            MS+NG+          L  + G++N   +YLTAE FGFKIN S  S+KK+Q+WT+  D  ++  F++SHL RYLSSDKDGKV CE E    + +F I    +  G+WA +S  Y  Y  G+E+ +SCF+++      W+  LA+HPQ ++ ++ R+RY  L  Q DE+  D  IPWG DSLITL +   GK ++ + D+R+L  DG L  +   N+ + LEL+ G      FKD EGKYL+  G TGT+KS +     KDE+F LE S+PQV  +A N ++ SI+Q V + ANQ D  + E FQ+E    +KK   RT  G YWT+ + + GI +++ +  E+++FDI  L   ++ +KASN  YV +KK G ++A  ++  + E  F   L+NRP+++ + + G V     +N +  + S Y+ F L   +DG Y +K  GN+  +W       +  DG   P+ F  +F       I A NGKY+RG+Q G +  D   +N +SLWE
Sbjct:    1 MSTNGIXA--------LKLQFGLINHENRYLTAEAFGFKINASGNSMKKKQIWTLEQDPDSQVVFLRSHLGRYLSSDKDGKVRCEEEVPNTDCRFLI--VMQSDGRWALQSEPYLRYFGGSEEYLSCFAQTIGESELWALHLALHPQANLLSVARKRYAHLSTQEDEISMDSNIPWGVDSLITLVYLE-GKYSLKTCDNRFLRNDGKLVMEHGPNTSFTLELKSGK---LAFKDCEGKYLSPNGPTGTLKSGRCTRPGKDELFDLEESHPQVVFQAANKRYVSIRQ-VCISANQDDETDMETFQMEIDKETKKCMFRTNGGNYWTLVT-HGGILSSATEIEENTMFDIEWLGR-RIALKASNGKYVCTKKNGQLAAVSDSLGEDEQ-FVLKLINRPILVLRGENGFVCHHKNSNTLHGSRSFYDIFTL-LFSDGGYQIK-SGNQ-KFWYVSSSGLVCTDGDK-PEDFFFEFVEYGRVGIKAQNGKYLRGDQGGTLMGDGLSVNASSLWE 487
[Close]
BLAST of Fascin vs. Ensembl Xenopus
Match: fscn1 (fascin actin-bundling protein 1 [Source:NCBI gene;Acc:394733])

HSP 1 Score: 349.362 bits (895), Expect = 3.256e-112
Identity = 208/495 (42.02%), Postives = 301/495 (60.81%), Query Frame = 2 
Query:  422 EMGIVNEAGKYLTAETFGFKINVSATSLKKRQLWTMIP---DKTAEYFFIKSHLNRYLSSDKDGKVSCEVEENGVEEQFFIEYCPKGTGKWAFKSVAYGYYLTGNEDRISCFSKSPSW---WSARLAIHPQVHMQNMKRQRYVRLQ--GDELHGDQVIPWGFDSLITLEHSTCGKVAVCSRDHRYLNKDGSLSDKITENSLYGLELRGGANPGFTFKDNEGKYLTLIGSTGTVKS-KNKVVSKDEIFTLEISYPQVGLRAHNGKFASIKQGVDLYANQADAEEKEIFQLEYQNSSKKWKIRTCDGKYWTVTSVNSGIKATSGDNNESSLFDIIHLTSGKVLIKASNNMYVSSKKLGLMSATGENAEDVESLFQAILLNRPMIIFKSDFGLVGIR--NNRVECNMSTYEAFQLETANDGNYMLKVCGNKDAYWRTGDDNGIKIDGSAPPQ-QFILQFDSGTHCAILASNGKYIRGEQNGLMKADSDEINKASLWEF 1870
            ++G+VN   KYLTAE FGFKIN SA+SLKK+Q+W++ P   D +A    ++SHL R+LS+DKDGKVS E E  G E +F +    +G G+WA +S AYG Y  G+EDRISCFS S S    W   LA+HPQ  + ++ R+RY RL   GDEL  ++ +PWG DSLITL      + ++ + DHR L  DGSL D    ++ Y L++  G      F+ N+G+YLT  G +GT+K+ KN    +DE+F LE S PQV L A NG+  S +QG+DL ANQ +  ++E FQLE    +K    RT  GKYWT+++ N GI+A++   N S  FD I     ++ +K  N  +V++KK G +SA+ +   + E LF   L+NRP+I+ + + G +G R     ++ N S Y+ F+LE  NDG Y LK    K  YW  G D  + +  S+P +  F  +F      AI   NG Y++G+  G++KA+++ I+ ++LWE+
Sbjct:    7 QLGLVNCNNKYLTAEAFGFKINASASSLKKKQVWSLEPAGEDTSA--VLLRSHLGRFLSADKDGKVSGESETAGPECRFLVS--AQGDGRWALQSEAYGRYFGGSEDRISCFSPSVSPAEKWGVHLAMHPQFTLYSVTRKRYARLSANGDELSVERDVPWGVDSLITLIFQD-NRYSIQTPDHRLLASDGSLRDGPGPDTGYTLDISSGK---VAFRANDGRYLTSSGPSGTMKAGKNSKAGRDELFVLERSCPQVVLTAGNGRNVSTRQGIDLSANQDEESDQETFQLEINKETKMCAFRTHTGKYWTLSN-NGGIQASASTLNNSCYFD-IDWCDRRITLKGVNGKFVTAKKNGQLSASIDTPAETE-LFLMKLINRPLIVLRGEHGFIGCRKMTGTLDSNRSIYDVFELE-FNDGAYSLKDSTGK--YWTVGSD--MSVTSSSPTRVDFYFEFCDYNKVAIKV-NGLYLKGDHAGVLKANAETIDSSTLWEY 484
[Close]
BLAST of Fascin vs. Ensembl Xenopus
Match: tldc2 (TBC/LysM-associated domain containing 2 [Source:Xenbase;Acc:XB-GENE-996510])

HSP 1 Score: 317.005 bits (811), Expect = 1.207e-99
Identity = 196/513 (38.21%), Postives = 300/513 (58.48%), Query Frame = 2 
Query:  365 MSSNGVNGSSESFNPILTWEMGIVNEAGKYLTAETFGFKINVSATSLKKRQLWTMIPDKT-AEYFFIKSH-LNRYLSSDKDGKVSCEVEENGVEEQFFIEYCPKGTGKWAFKSVAYGYYLTGNEDRISCFSKSPS---WWSARLAIHPQVHMQNMKRQRYVRL--QGDELHGDQVIPWGFDSLITLEHSTCGKVAVCSRDHRYLNKDGSLSDKITENSLYGLELRGGANPGFTFKDNEGKYLTLIGSTGTVKS-KNKVVSKDEIFTLEISYPQVGLRAHNGKFASIKQGVDLYANQADAEEKEIFQLEYQNSSKKWKIRTCDGKYWTVTSVNSGIKATSGDNNESSLFDIIHLTSGKVLIKASNNMYVSSKKLGLMSATGENA-EDVESLFQAILLNRPMIIFKSDFGLVGIR--NNRVECNMSTYEAFQLETANDGNYMLKVCGNKDAYWRTGDDNGIKIDGSAPPQQFILQFDSGTHCAILASNGKYIRGEQNGLMKADSDEINKASLWEF 1870
            M +NG++        IL  + G++N   +YLT E FGFK+  +A SLKK+Q+WT+  D+  +   ++KSH L RYLS+DKDG VSCE E+   + +F I    +  G+WA +S  +  +  G+ D +SCF+++ +    W+  LAIHPQ ++ ++ R+RY  L  Q DE+  D  IPWG DSLITL +    K  + + D+RYL  DG L  +  E + Y LE + G      FKD  GKYLT +G TGT+KS ++    KDE+F LE S+PQV   A N ++ S +QGV++ ANQ +  + E FQ++    + K    T  GKYWT+ S + GI++T+ +   +++FD I     KV +KASN  Y+ +KK G ++A G+   ED E + +  L+NRP+++ + D G V     +N ++ N S+Y+ FQ+   N+G Y +K  G K  +W    +  I  DG    + F    +     AI   NG+Y+RG+Q G +KAD++ +N A+LWE+
Sbjct:    1 MPTNGIH-------QILKIQFGLINCDNRYLTGEAFGFKVYATAPSLKKKQIWTLEQDQVDSSVVYLKSHHLARYLSADKDGNVSCEAEKPEEDCRFTIS--AQSDGRWALQSDPHKRFFGGSVDMLSCFAQTITETELWAVHLAIHPQANLLSVSRRRYAHLTPQEDEVSTDSNIPWGVDSLITLVYQD-KKYCLKTCDNRYLRNDGKLVKEPDEGTGYTLEFKAGK---LAFKDCSGKYLTPMGPTGTLKSGRSSKPGKDELFDLEESHPQVVFMASNRRYISTRQGVNVSANQDEETDYETFQMQINKETNKCSFHTNAGKYWTLVS-HGGIQSTATEIAANTMFD-IEWRGRKVALKASNGKYICTKKNGQLAAVGDTVGEDEEFILK--LINRPILVLRGDLGFVCHHKTSNMLDANRSSYDVFQI-IFNNGAYQIKGQGGK--FWYISSNGTICSDGDMSEEFFFEFREH-NRVAIKGKNGRYLRGDQAGTLKADAESVNSATLWEY 492
[Close]
BLAST of Fascin vs. Ensembl Xenopus
Match: tldc2 (TBC/LysM-associated domain containing 2 [Source:Xenbase;Acc:XB-GENE-996510])

HSP 1 Score: 282.722 bits (722), Expect = 8.354e-87
Identity = 172/442 (38.91%), Postives = 263/442 (59.50%), Query Frame = 2 
Query:  365 MSSNGVNGSSESFNPILTWEMGIVNEAGKYLTAETFGFKINVSATSLKKRQLWTMIPDKT-AEYFFIKSH-LNRYLSSDKDGKVSCEVEENGVEEQFFIEYCPKGTGKWAFKSVAYGYYLTGNEDRISCFSKSPS---WWSARLAIHPQVHMQNMKRQRYVRL--QGDELHGDQVIPWGFDSLITLEHSTCGKVAVCSRDHRYLNKDGSLSDKITENSLYGLELRGGANPGFTFKDNEGKYLTLIGSTGTVKS-KNKVVSKDEIFTLEISYPQVGLRAHNGKFASIKQGVDLYANQADAEEKEIFQLEYQNSSKKWKIRTCDGKYWTVTSVNSGIKATSGDNNESSLFDIIHLTSGKVLIKASNNMYVSSKKLGLMSATGENA-EDVESLFQAILLNRPMIIFKSDFGLVGIR--NNRVECNMSTYEAFQLETANDGNYMLK 1657
            M +NG++        IL  + G++N   +YLT E FGFK+  +A SLKK+Q+WT+  D+  +   ++KSH L RYLS+DKDG VSCE E+   + +F I    +  G+WA +S  +  +  G+ D +SCF+++ +    W+  LAIHPQ ++ ++ R+RY  L  Q DE+  D  IPWG DSLITL +    K  + + D+RYL  DG L  +  E + Y LE + G      FKD  GKYLT +G TGT+KS ++    KDE+F LE S+PQV   A N ++ S +QGV++ ANQ +  + E FQ++    + K    T  GKYWT+ S + GI++T+ +   +++FD I     KV +KASN  Y+ +KK G ++A G+   ED E + +  L+NRP+++ + D G V     +N ++ N S+Y+ FQ+   N+G Y +K
Sbjct:    1 MPTNGIH-------QILKIQFGLINCDNRYLTGEAFGFKVYATAPSLKKKQIWTLEQDQVDSSVVYLKSHHLARYLSADKDGNVSCEAEKPEEDCRFTIS--AQSDGRWALQSDPHKRFFGGSVDMLSCFAQTITETELWAVHLAIHPQANLLSVSRRRYAHLTPQEDEVSTDSNIPWGVDSLITLVYQD-KKYCLKTCDNRYLRNDGKLVKEPDEGTGYTLEFKAGK---LAFKDCSGKYLTPMGPTGTLKSGRSSKPGKDELFDLEESHPQVVFMASNRRYISTRQGVNVSANQDEETDYETFQMQINKETNKCSFHTNAGKYWTLVS-HGGIQSTATEIAANTMFD-IEWRGRKVALKASNGKYICTKKNGQLAAVGDTVGEDEEFILK--LINRPILVLRGDLGFVCHHKTSNMLDANRSSYDVFQI-IFNNGAYQIK 424
[Close]
BLAST of Fascin vs. Ensembl Mouse
Match: Fscn1 (fascin actin-bundling protein 1 [Source:MGI Symbol;Acc:MGI:1352745])

HSP 1 Score: 333.569 bits (854), Expect = 3.753e-106
Identity = 201/509 (39.49%), Postives = 303/509 (59.53%), Query Frame = 2 
Query:  380 VNGSSESFNPILTWEMGIVNEAGKYLTAETFGFKINVSATSLKKRQLWTM--IPDKT-AEYFFIKSHLNRYLSSDKDGKVSCEVEENGVEEQFFIEYCPKGTGKWAFKSVAYGYYLTGNEDRISCFSKSPSW---WSARLAIHPQVHMQNMKRQRYVRLQG---DELHGDQVIPWGFDSLITLEHSTCGKVAVCSRDHRYLNKDGSLSDKITENSLYGLELRGGANPGFTFKDNEGKYLTLIGSTGTVKS-KNKVVSKDEIFTLEISYPQVGLRAHNGKFASIKQGVDLYANQADAEEKEIFQLEYQNSSKKWKIRTCDGKYWTVTSVNSGIKATSGDNNESSLFDIIHLTSGKVLIKASNNMYVSSKKLGLMSATGENAEDVESLFQAILLNRPMIIFKSDFGLVGIR--NNRVECNMSTYEAFQLETANDGNYMLKVCGNKDAYWRTGDDNGIKIDGSAPPQQFILQFDSGTHCAILASNGKYIRGEQNGLMKADSDEINKASLWEF 1870
             NG++E+    +  + G+++   KYLTAE FGFK+N SA+SLKK+Q+WT+   PD+  +    ++SHL RYL++DKDG V+CE E    + +F +       G+W+ +S A+  Y  G EDR+SCF++S S    WS  +A+HPQV++ ++ R+RY  L     DE+  D+ +PWG DSLITL      + +V + DHR+L  DG L  +    + + LE R G      F+D EG+YL   G +GT+K+ K   V KDE+F LE S  QV L+A N +  S +QG+DL ANQ +  ++E FQLE    ++K   RT  GKYWT+T+   G+++T+   N S  FD I     ++ ++ASN  +V++KK G ++A+ E A D E LF   L+NRP+I+F+ + G +G R     ++ N S+Y+ FQLE  NDG Y +K    K  YW  G D+ +      P   F L+F      A L   G+Y++G+  G++KA ++ I+ ASLWE+
Sbjct:    3 ANGTAEA----VQIQFGLISCGNKYLTAEAFGFKVNASASSLKKKQIWTLEQPPDEAGSAAVCLRSHLGRYLAADKDGNVTCEREVPDGDCRFLV--VAHDDGRWSLQSEAHRRYFGGTEDRLSCFAQSVSPAEKWSVHIAMHPQVNIYSVTRKRYAHLSARPADEIAVDRDVPWGVDSLITLAFQD-QRYSVQTSDHRFLRHDGRLVARPEPATGFTLEFRSGK---VAFRDCEGRYLAPSGPSGTLKAGKATKVGKDELFALEQSCAQVVLQAANERNVSTRQGMDLSANQDEETDQETFQLEIDRDTRKCAFRTHTGKYWTLTATG-GVQSTASTKNASCYFD-IEWCDRRITLRASNGKFVTAKKNGQLAASVETAGDSE-LFLMKLINRPIIVFRGEHGFIGCRKVTGTLDANRSSYDVFQLEF-NDGAYNIKDSTGK--YWTVGSDSSVTSSSDTPV-DFFLEFCDYNKVA-LKVGGRYLKGDHAGVLKACAETIDPASLWEY 493
[Close]
BLAST of Fascin vs. Ensembl Mouse
Match: Fscn2 (fascin actin-bundling protein 2 [Source:MGI Symbol;Acc:MGI:2443337])

HSP 1 Score: 330.872 bits (847), Expect = 4.542e-105
Identity = 191/512 (37.30%), Postives = 304/512 (59.38%), Query Frame = 2 
Query:  365 MSSNGVNGSSESFNPILTWEMGIVNEAGKYLTAETFGFKINVSATSLKKRQLWTMIPD--KTAEYFFIKSHLNRYLSSDKDGKVSCEVEENGVEEQFFIEYCPKGTGKWAFKSVAYGYYLTGNEDRISCFSK--SPS-WWSARLAIHPQVHMQNMKRQRYVR--LQGDELHGDQVIPWGFDSLITLEHSTCGKVAVCSRDHRYLNKDGSLSDKITENSLYGLELRGGANPGFTFKDNEGKYLTLIGSTGTVKS-KNKVVSKDEIFTLEISYPQVGLRAHNGKFASIKQGVDLYANQADAEEKEIFQLEYQNSSKKWKIRTCDGKYWTVTSVNSGIKATSGDNNESSLFDIIHLTSGKVLIKASNNMYVSSKKLGLMSATGENAEDVESLFQAILLNRPMIIFKSDFGLVGIR--NNRVECNMSTYEAFQLETANDGNYMLKVCGNKDAYWRTGDDNGIKIDGSAPPQQFILQFDSGTHCAILASNGKYIRGEQNGLMKADSDEINKASLWEF 1870
            M +NG++        +L  + G+VN+A +YLTAE+FGFK+N SA SLK++Q+W + PD  +     F  SHL RYLS+++DG+V+CE+++ G + +F +   P+  G+W  +S  +G +  G EDR+SCF+   SP+  W+  LAIHPQ H+ ++ R+RYV   LQ DE+  D  +PWG D+L+TL   +  +  + S D RYL  DG L  +   ++ Y LE + G      FKD +G+YL  +G  GT+K+ +N   SKDE+F LE S+PQV L A N ++ S++QG+++ ANQ +    E F ++    +KK    +  G YWT+ + + GI+AT+   + +++F+ I     +V +KASN  +V  KK G ++A  +   + E LF   L+NRP+++ +   G V  R  +N+++ N STY+ F L +  DG Y ++  G    +W TG    +  DG    + F+ +F      AI A +GKY+RG  +GL++AD+D     +LWE+
Sbjct:    1 MPTNGLH-------QVLKIQFGLVNDADRYLTAESFGFKVNASAASLKRKQIWVLEPDPGQGTAVLFRSSHLGRYLSAEEDGRVACEMDQPGRDCRFLV--LPQPDGRWVLQSEPHGRFFGGIEDRLSCFATAISPAELWTVHLAIHPQAHLLSVSRRRYVHLCLQEDEMAADGDMPWGVDALVTLIFQS-RRYCLKSYDSRYLRSDGRLVWEPEAHACYTLEFKAGK---LAFKDCDGRYLAPVGPAGTLKAGRNTRPSKDELFDLEQSHPQVVLVAANRRYISVRQGINVSANQDEELGHETFLMQIDQETKKCTFYSSTGGYWTLVT-HGGIQATATQVSANTMFE-IEWHGRRVALKASNGRFVCMKKNGQLAAISDFVGEDE-LFTLKLINRPLLVLRGLDGFVCHRRGSNQLDTNRSTYDVFHL-SFRDGAYQIR--GRGGGFWYTGSHGSVCSDGDL-AEDFLFEFRERGRLAIRALSGKYLRGGASGLLRADADLPVGEALWEY 492
[Close]
BLAST of Fascin vs. Ensembl Mouse
Match: Fscn1 (fascin actin-bundling protein 1 [Source:MGI Symbol;Acc:MGI:1352745])

HSP 1 Score: 172.17 bits (435), Expect = 1.898e-47
Identity = 108/279 (38.71%), Postives = 164/279 (58.78%), Query Frame = 2 
Query: 1043 FKDNEGKYLTLIGSTGTVKS-KNKVVSKDEIFTLEISYPQVGLRAHNGKFASIKQGVDLYANQADAEEKEIFQLEYQNSSKKWKIRTCDGKYWTVTSVNSGIKATSGDNNESSLFDIIHLTSGKVLIKASNNMYVSSKKLGLMSATGENAEDVESLFQAILLNRPMIIFKSDFGLVGIR--NNRVECNMSTYEAFQLETANDGNYMLKVCGNKDAYWRTGDDNGIKIDGSAPPQQFILQFDSGTHCAILASNGKYIRGEQNGLMKADSDEINKASLWEF 1870
             + + G+YL   G +GT+K+ K   V KDE+F LE S  QV L+A N +  S +QG+DL ANQ +  ++E FQLE    ++K   RT  GKYWT+T+   G+++T+   N S  FD I     ++ ++ASN  +V++KK G ++A+ E A D E LF   L+NRP+I+F+ + G +G R     ++ N S+Y+ FQLE  NDG Y +K    K  YW  G D+ +      P   F L+F      A L   G+Y++G+  G++KA ++ I+ ASLWE+
Sbjct:   62 LRSHLGRYLAPSGPSGTLKAGKATKVGKDELFALEQSCAQVVLQAANERNVSTRQGMDLSANQDEETDQETFQLEIDRDTRKCAFRTHTGKYWTLTATG-GVQSTASTKNASCYFD-IEWCDRRITLRASNGKFVTAKKNGQLAASVETAGDSE-LFLMKLINRPIIVFRGEHGFIGCRKVTGTLDANRSSYDVFQLEF-NDGAYNIKDSTGK--YWTVGSDSSVTSSSDTPV-DFFLEFCDYNKVA-LKVGGRYLKGDHAGVLKACAETIDPASLWEY 332

HSP 2 Score: 70.0922 bits (170), Expect = 2.378e-12
Identity = 79/321 (24.61%), Postives = 138/321 (42.99%), Query Frame = 2 
Query:  380 VNGSSESFNPILTWEMGIVNEAGKYLTAETFGFKINVSATSLKKRQLWTM--IPDKT-AEYFFIKSHLNRYLS-SDKDGKVSC-EVEENGVEEQFFIEYCPKGTGKWAFKSVAYGYYLTGNEDRISCFSKSPSWWSARLAIHPQVHMQNMKRQRYVRLQGDELHGDQVIPWGFDSLITLEHSTCGKVAVCSRDHRYLNKDGSLSDKITENSLYGLELRGGANPGFTFKDNEGKYLTLIGSTGTVKSKNKVVSKDEIFTLE-ISYPQVGLRAHNGKFASIKQGVDLYANQADAEEKEIFQLEYQNSSKKWKIRTCDGKYWTV 1324
             NG++E+    +  + G+++   KYLTAE FGFK+N SA+SLKK+Q+WT+   PD+  +    ++SHL RYL+ S   G +   +  + G +E F +E           +S A       NE  +S  ++     SA            ++  R  R      H  +   W   +   ++ +   K A C  D  + ++                          T + + GK++T     G + +  +     E+F ++ I+ P +  R  +G     K    L AN++     ++FQLE+ + +  + I+   GKYWTV
Sbjct:    3 ANGTAEA----VQIQFGLISCGNKYLTAEAFGFKVNASASSLKKKQIWTLEQPPDEAGSAAVCLRSHLGRYLAPSGPSGTLKAGKATKVGKDELFALE-----------QSCAQVVLQAANERNVS--TRQGMDLSANQDEETDQETFQLEIDRDTRKCAFRTHTGKY--WTLTATGGVQSTASTKNASCYFDIEWCDRR------------------------ITLRASNGKFVT-AKKNGQLAASVETAGDSELFLMKLINRPIIVFRGEHGFIGCRKVTGTLDANRS---SYDVFQLEFNDGA--YNIKDSTGKYWTV 274
[Close]
BLAST of Fascin vs. Ensembl Mouse
Match: Fscn1 (fascin actin-bundling protein 1 [Source:MGI Symbol;Acc:MGI:1352745])

HSP 1 Score: 151.754 bits (382), Expect = 3.375e-41
Identity = 93/242 (38.43%), Postives = 143/242 (59.09%), Query Frame = 2 
Query: 1151 YPQVGLRAHNGKFASIKQGVDLYANQADAEEKEIFQLEYQNSSKKWKIRTCDGKYWTVTSVNSGIKATSGDNNESSLFDIIHLTSGKVLIKASNNMYVSSKKLGLMSATGENAEDVESLFQAILLNRPMIIFKSDFGLVGIR--NNRVECNMSTYEAFQLETANDGNYMLKVCGNKDAYWRTGDDNGIKIDGSAPPQQFILQFDSGTHCAILASNGKYIRGEQNGLMKADSDEINKASLWEF 1870
            +PQV L+A N +  S +QG+DL ANQ +  ++E FQLE    ++K   RT  GKYWT+T+   G+++T+   N S  FD I     ++ ++ASN  +V++KK G ++A+ E A D E LF   L+NRP+I+F+ + G +G R     ++ N S+Y+ FQLE  NDG Y +K    K  YW  G D+ +      P   F L+F      A L   G+Y++G+  G++KA ++ I+ ASLWE+
Sbjct:    8 HPQVVLQAANERNVSTRQGMDLSANQDEETDQETFQLEIDRDTRKCAFRTHTGKYWTLTAT-GGVQSTASTKNASCYFD-IEWCDRRITLRASNGKFVTAKKNGQLAASVETAGDSE-LFLMKLINRPIIVFRGEHGFIGCRKVTGTLDANRSSYDVFQLE-FNDGAYNIKDSTGK--YWTVGSDSSVTSSSDTPV-DFFLEFCDYNKVA-LKVGGRYLKGDHAGVLKACAETIDPASLWEY 241
[Close]
BLAST of Fascin vs. Ensembl Mouse
Match: Fscn3 (fascin actin-bundling protein 3 [Source:MGI Symbol;Acc:MGI:1890386])

HSP 1 Score: 134.806 bits (338), Expect = 5.483e-33
Identity = 120/499 (24.05%), Postives = 210/499 (42.08%), Query Frame = 2 
Query:  422 EMGIVNEAGKYLTAETFGFKINVSATSLKKRQLWTMIPDKTAE---YFFIKSHLNRYLSSDKDGKVSCEVEENGVEEQFFIEYCPKGTGKWAFKSVAYGYYLTGNEDRISCFSKSPS---WWSARLAIHPQVHMQNMKRQRYVRLQGDELHG----DQVIPWGFDSLITLEHSTCGKVAVCSRDHRYLNKDGSLSDKITENSLYGLELRGGANPGFTFKDNEGKYLTLIGSTGTVKSKNKVVSKDEIFTLEISYPQVGLRAHNGKFASIKQGVDLYANQADAEEKEIFQLEYQNSSKKWKIRTCDGKYWTVTSVNSGIKATSGDNNESSLFDIIHLTSGKVLIKASNNMYVSSKKLGLMSA----TGENAEDVESLFQAILLNRPMIIFKSDFGLVGIRNNR--VECNMSTYEAFQLETANDGNYMLKVCGNKDAYWRTGDDNGIKIDGSAPPQQFILQFDSGTHCAILASNGKYIRGEQNGLMKADSDEINKASLWEF 1870
             +G+++ AG YLT E +   +  SA SL +RQ W ++     E      +KS    YL  + DG V            F + +     GKW  + +  G YL  + + + C S+  S    W+ R A+H  V + +     Y R   D   G    D  IP   +    L H   G   + +  H +L++   L  + +  + + +++R          D EG  L   GS   +   +  +  +E F L+     V L++ + +F S+    ++ A      +  +FQ E  + +   ++R+ +G Y+     +  I A  G   ES  F  +H   GK+ +++ N  ++     GL+ A     G N E           NRP ++ +  +G VG  ++   ++CNM   +  QL     G Y  +  G   ++W        +  G      F ++    +   +LA NG Y+R +++G + ADS+EI K  +WEF
Sbjct:   17 RVGLISWAGTYLTFEAYKSSVTASAKSLGRRQTWELLVSNEHESQAVIRLKSLQGLYLLCEADGTVCYGRPRTSHHGCFLLRF--HRNGKWTLQCIISGRYLESDGEDVFCNSRVLSAYHMWTPRPALHVHVILYSPIYHSYAR--ADHTVGRIWVDAAIP-CLEECGFLLHFQDGCYHLETSTHHFLSRVDRLVPQRSSQTAFHMQVRPRGLVALC--DGEGGTLYPQGSHLLLGMGSAPMKGEEWFVLQHFPTWVSLKSKSRRFLSVIYDAEVCAASERLTQMSLFQYECDSETPTLQLRSANG-YYLAQRRHRAIIA-DGHPMESDTFFRVHWNCGKITLQSPNGRFLGIASDGLLMANVTIPGPNEE-----LGIRFANRPFLVLRGRYGYVGSSSDHDLLKCNMDQPDCIQLLPCRQGIYHFQAQGG--SFWSITSFGTFRPWGKFA-LNFCIELQGSSLLTVLAPNGFYLRADRSGTLLADSEEITKECIWEF 498
[Close]
BLAST of Fascin vs. UniProt/SwissProt
Match: sp|Q16658|FSCN1_HUMAN (Fascin OS=Homo sapiens OX=9606 GN=FSCN1 PE=1 SV=3)

HSP 1 Score: 350.132 bits (897), Expect = 1.185e-111
Identity = 205/509 (40.28%), Postives = 304/509 (59.72%), Query Frame = 2 
Query:  380 VNGSSESFNPILTWEMGIVNEAGKYLTAETFGFKINVSATSLKKRQLWTM--IPDKT-AEYFFIKSHLNRYLSSDKDGKVSCEVEENGVEEQFFIEYCPKGTGKWAFKSVAYGYYLTGNEDRISCFSKSPSW---WSARLAIHPQVHMQNMKRQRYVRLQG---DELHGDQVIPWGFDSLITLEHSTCGKVAVCSRDHRYLNKDGSLSDKITENSLYGLELRGGANPGFTFKDNEGKYLTLIGSTGTVKS-KNKVVSKDEIFTLEISYPQVGLRAHNGKFASIKQGVDLYANQADAEEKEIFQLEYQNSSKKWKIRTCDGKYWTVTSVNSGIKATSGDNNESSLFDIIHLTSGKVLIKASNNMYVSSKKLGLMSATGENAEDVESLFQAILLNRPMIIFKSDFGLVGIR--NNRVECNMSTYEAFQLETANDGNYMLKVCGNKDAYWRTGDDNGIKIDGSAPPQQFILQFDSGTHCAILASNGKYIRGEQNGLMKADSDEINKASLWEF 1870
             NG++E+    +  + G++N   KYLTAE FGFK+N SA+SLKK+Q+WT+   PD+  +    ++SHL RYL++DKDG V+CE E  G + +F I       G+W+ +S A+  Y  G EDR+SCF+++ S    WS  +A+HPQV++ ++ R+RY  L     DE+  D+ +PWG DSLITL      + +V + DHR+L  DG L  +    + Y LE R G      F+D EG+YL   G +GT+K+ K   V KDE+F LE S  QV L+A N +  S +QG+DL ANQ +  ++E FQLE    +KK   RT  GKYWT+T+   G+++T+   N S  FD I     ++ ++ASN  +V+SKK G ++A+ E A D E LF   L+NRP+I+F+ + G +G R     ++ N S+Y+ FQLE  NDG Y +K    K  YW  G D+ +   G   P  F  +F      AI    G+Y++G+  G++KA ++ ++ ASLWE+
Sbjct:    3 ANGTAEA----VQIQFGLINCGNKYLTAEAFGFKVNASASSLKKKQIWTLEQPPDEAGSAAVCLRSHLGRYLAADKDGNVTCEREVPGPDCRFLI--VAHDDGRWSLQSEAHRRYFGGTEDRLSCFAQTVSPAEKWSVHIAMHPQVNIYSVTRKRYAHLSARPADEIAVDRDVPWGVDSLITLAFQD-QRYSVQTADHRFLRHDGRLVARPEPATGYTLEFRSGK---VAFRDCEGRYLAPSGPSGTLKAGKATKVGKDELFALEQSCAQVVLQAANERNVSTRQGMDLSANQDEETDQETFQLEIDRDTKKCAFRTHTGKYWTLTATG-GVQSTASSKNASCYFD-IEWRDRRITLRASNGKFVTSKKNGQLAASVETAGDSE-LFLMKLINRPIIVFRGEHGFIGCRKVTGTLDANRSSYDVFQLEF-NDGAYNIKDSTGK--YWTVGSDSAVTSSGDT-PVDFFFEFCDYNKVAIKV-GGRYLKGDHAGVLKASAETVDPASLWEY 493
[Close]
BLAST of Fascin vs. UniProt/SwissProt
Match: sp|Q24524|SING_DROME (Protein singed OS=Drosophila melanogaster OX=7227 GN=sn PE=1 SV=1)

HSP 1 Score: 347.821 bits (891), Expect = 1.744e-110
Identity = 191/496 (38.51%), Postives = 290/496 (58.47%), Query Frame = 2 
Query:  419 WEMGIVNEAGKYLTAETFGFKINVSATSLKKRQLWTMIPDKTAE-YFFIKSHLNRYLSSDKDGKVSCEVEENGVEEQFFIEYCPKGTGKWAFKSVAYGYYLTGNEDRISCFSKSP---SWWSARLAIHPQVHMQNMKRQRYVRL--QGDELHGDQVIPWGFDSLITLEHST--CGKVAVCSRDHRYLNKDGSLSDKITENSLYGLELRGGANPGFTFKDNEGKYLTLIGSTGTVKSKNKVVSKDEIFTLEISYPQVGLRAH-NGKFASIKQGVDLYANQADAEEKEIFQLEYQNSSKKWKIRTCDGKYWTVTSVNSGIKATSGDNNESSLFDIIHLTSGKVLIKASNNMYVSSKKLGLMSATGENAEDVESLFQAILLNRPMIIFKSDFGLVGIR---NNRVECNMSTYEAFQLETANDGNYMLKVCGNKDAYWRTGDDNGIKIDGSAPPQQFILQFDSGTHCAILASNGKYIRGEQNGLMKADSDEINKASLWEF 1870
            W +G++N   KY+TAETFGFK+N +  SLKK+QLWT+ P  T E   +++SHLN+YLS D+ G V CE +E     +F I     G+G+WA K+ + GY+L G  D++ C +K+P    +W+  LA  PQV+++++ R+R+  L    DE+H D  IPWG D+L TLE      G+ A+ + +++YLN +G L     E+ L+  E  GG       +D +G+YL+ IGS   +KS++  V++DE+F+LE S PQ    A  N ++ S+KQGVD+ ANQ +  E E FQLEY  S+ +W +RT   +YW + S   GI+AT       +LF++I    G +  +A+N  ++++K+ G + AT E+ E++ + F   L+NRP+++ K + G VG R   N ++ECN +TYE   +E A  G   LK    K  YWR  +   I +D  AP   F L+    T   I +  GKY+   +NG  K   D  + A+ WEF
Sbjct:   25 WTIGLINGQHKYMTAETFGFKLNANGASLKKKQLWTLEPSNTGESIIYLRSHLNKYLSVDQFGNVLCESDERDAGSRFQISISEDGSGRWALKNESRGYFLGGTPDKLVCTAKTPGASEFWTVHLAARPQVNLRSIGRKRFAHLSESQDEIHVDANIPWGEDTLFTLEFRAEEGGRYALHTCNNKYLNANGKLQVVCNEDCLFSAEYHGGH---LALRDRQGQYLSPIGSKAVLKSRSSSVTRDELFSLEDSLPQASFIAGLNLRYVSVKQGVDVTANQDEVGENETFQLEYDWSAHRWALRTTQDRYWCL-SAGGGIQATGNRRCADALFELIWHGDGSLSFRANNGKFLATKRSGHLFATSESIEEI-AKFYFYLINRPILVLKCEQGFVGYRTPGNLKLECNKATYETILVERAQKGLVHLKAHSGK--YWRI-EGESISVDADAPSDGFFLELREPTRICIRSQQGKYLGATKNGAFKLLDDGTDSATQWEF 512
[Close]
BLAST of Fascin vs. UniProt/SwissProt
Match: sp|Q61553|FSCN1_MOUSE (Fascin OS=Mus musculus OX=10090 GN=Fscn1 PE=1 SV=4)

HSP 1 Score: 333.569 bits (854), Expect = 2.626e-105
Identity = 201/509 (39.49%), Postives = 303/509 (59.53%), Query Frame = 2 
Query:  380 VNGSSESFNPILTWEMGIVNEAGKYLTAETFGFKINVSATSLKKRQLWTM--IPDKT-AEYFFIKSHLNRYLSSDKDGKVSCEVEENGVEEQFFIEYCPKGTGKWAFKSVAYGYYLTGNEDRISCFSKSPSW---WSARLAIHPQVHMQNMKRQRYVRLQG---DELHGDQVIPWGFDSLITLEHSTCGKVAVCSRDHRYLNKDGSLSDKITENSLYGLELRGGANPGFTFKDNEGKYLTLIGSTGTVKS-KNKVVSKDEIFTLEISYPQVGLRAHNGKFASIKQGVDLYANQADAEEKEIFQLEYQNSSKKWKIRTCDGKYWTVTSVNSGIKATSGDNNESSLFDIIHLTSGKVLIKASNNMYVSSKKLGLMSATGENAEDVESLFQAILLNRPMIIFKSDFGLVGIR--NNRVECNMSTYEAFQLETANDGNYMLKVCGNKDAYWRTGDDNGIKIDGSAPPQQFILQFDSGTHCAILASNGKYIRGEQNGLMKADSDEINKASLWEF 1870
             NG++E+    +  + G+++   KYLTAE FGFK+N SA+SLKK+Q+WT+   PD+  +    ++SHL RYL++DKDG V+CE E    + +F +       G+W+ +S A+  Y  G EDR+SCF++S S    WS  +A+HPQV++ ++ R+RY  L     DE+  D+ +PWG DSLITL      + +V + DHR+L  DG L  +    + + LE R G      F+D EG+YL   G +GT+K+ K   V KDE+F LE S  QV L+A N +  S +QG+DL ANQ +  ++E FQLE    ++K   RT  GKYWT+T+   G+++T+   N S  FD I     ++ ++ASN  +V++KK G ++A+ E A D E LF   L+NRP+I+F+ + G +G R     ++ N S+Y+ FQLE  NDG Y +K    K  YW  G D+ +      P   F L+F      A L   G+Y++G+  G++KA ++ I+ ASLWE+
Sbjct:    3 ANGTAEA----VQIQFGLISCGNKYLTAEAFGFKVNASASSLKKKQIWTLEQPPDEAGSAAVCLRSHLGRYLAADKDGNVTCEREVPDGDCRFLV--VAHDDGRWSLQSEAHRRYFGGTEDRLSCFAQSVSPAEKWSVHIAMHPQVNIYSVTRKRYAHLSARPADEIAVDRDVPWGVDSLITLAFQD-QRYSVQTSDHRFLRHDGRLVARPEPATGFTLEFRSGK---VAFRDCEGRYLAPSGPSGTLKAGKATKVGKDELFALEQSCAQVVLQAANERNVSTRQGMDLSANQDEETDQETFQLEIDRDTRKCAFRTHTGKYWTLTATG-GVQSTASTKNASCYFD-IEWCDRRITLRASNGKFVTAKKNGQLAASVETAGDSE-LFLMKLINRPIIVFRGEHGFIGCRKVTGTLDANRSSYDVFQLEF-NDGAYNIKDSTGK--YWTVGSDSSVTSSSDTPV-DFFLEFCDYNKVA-LKVGGRYLKGDHAGVLKACAETIDPASLWEY 493
[Close]
BLAST of Fascin vs. UniProt/SwissProt
Match: sp|P85845|FSCN1_RAT (Fascin OS=Rattus norvegicus OX=10116 GN=Fscn1 PE=1 SV=2)

HSP 1 Score: 331.257 bits (848), Expect = 2.255e-104
Identity = 200/509 (39.29%), Postives = 302/509 (59.33%), Query Frame = 2 
Query:  380 VNGSSESFNPILTWEMGIVNEAGKYLTAETFGFKINVSATSLKKRQLWTM--IPDKT-AEYFFIKSHLNRYLSSDKDGKVSCEVEENGVEEQFFIEYCPKGTGKWAFKSVAYGYYLTGNEDRISCFSKSPSW---WSARLAIHPQVHMQNMKRQRYVRLQG---DELHGDQVIPWGFDSLITLEHSTCGKVAVCSRDHRYLNKDGSLSDKITENSLYGLELRGGANPGFTFKDNEGKYLTLIGSTGTVKS-KNKVVSKDEIFTLEISYPQVGLRAHNGKFASIKQGVDLYANQADAEEKEIFQLEYQNSSKKWKIRTCDGKYWTVTSVNSGIKATSGDNNESSLFDIIHLTSGKVLIKASNNMYVSSKKLGLMSATGENAEDVESLFQAILLNRPMIIFKSDFGLVGIR--NNRVECNMSTYEAFQLETANDGNYMLKVCGNKDAYWRTGDDNGIKIDGSAPPQQFILQFDSGTHCAILASNGKYIRGEQNGLMKADSDEINKASLWEF 1870
             NG++E+    +  + G+++   KYLTAE FGFK+N SA+SLKK+Q+WT+   PD+  +    ++SHL  YL++DKDG V+CE E    + +F +       G+W+ +S A+  Y  G EDR+SCF++S S    WS  +A+HPQV++ ++ R+RY  L     DE+  D+ +PWG DSLITL      + +V + DHR+L  DG L  +    + + LE R G      F+D EG+YL   G +GT+K+ K   V KDE+F LE S  QV L+A N +  S +QG+DL ANQ +  ++E FQLE    ++K   RT  GKYWT+T+   G+++T+   N S  FD I     ++ ++ASN  +V++KK G ++AT E A D E LF   L+NRP+I+F+ + G +G R     ++ N S+Y+ FQLE  NDG Y +K    K  YW  G D+ +       P  F L+F      A L   G+Y++G+  G++KA ++ I+ A+LWE+
Sbjct:    3 ANGTAEA----VQIQFGLISCGNKYLTAEAFGFKVNASASSLKKKQIWTLEQPPDEAGSAAVCLRSHLGPYLAADKDGNVTCEREVPDGDCRFLV--VAHDDGRWSLQSEAHRRYFGGTEDRLSCFAQSVSPAEKWSVHIAMHPQVNIYSVTRKRYAHLSARPADEIAVDRDVPWGVDSLITLAFQD-QRYSVQTSDHRFLRHDGRLVARPEPATGFTLEFRSGK---VAFRDCEGRYLAPSGPSGTLKAGKATKVGKDELFALEQSCAQVVLQAANERNVSTRQGMDLSANQDEETDQETFQLEIDRDTRKCAFRTHTGKYWTLTATG-GVQSTASTKNASCYFD-IEWCERRITLRASNGKFVTAKKNGQLAATVETAGDSE-LFLMKLINRPIIVFRGEHGFIGCRKVTGTLDANRSSYDVFQLEF-NDGAYNIKDSTGK--YWTVGSDSSVTSSSDT-PVDFFLEFCDYNKVA-LKVGGRYLKGDHAGVLKACAETIDPATLWEY 493
[Close]
BLAST of Fascin vs. UniProt/SwissProt
Match: sp|Q32M02|FSCN2_MOUSE (Fascin-2 OS=Mus musculus OX=10090 GN=Fscn2 PE=2 SV=1)

HSP 1 Score: 330.872 bits (847), Expect = 3.177e-104
Identity = 191/512 (37.30%), Postives = 304/512 (59.38%), Query Frame = 2 
Query:  365 MSSNGVNGSSESFNPILTWEMGIVNEAGKYLTAETFGFKINVSATSLKKRQLWTMIPD--KTAEYFFIKSHLNRYLSSDKDGKVSCEVEENGVEEQFFIEYCPKGTGKWAFKSVAYGYYLTGNEDRISCFSK--SPS-WWSARLAIHPQVHMQNMKRQRYVR--LQGDELHGDQVIPWGFDSLITLEHSTCGKVAVCSRDHRYLNKDGSLSDKITENSLYGLELRGGANPGFTFKDNEGKYLTLIGSTGTVKS-KNKVVSKDEIFTLEISYPQVGLRAHNGKFASIKQGVDLYANQADAEEKEIFQLEYQNSSKKWKIRTCDGKYWTVTSVNSGIKATSGDNNESSLFDIIHLTSGKVLIKASNNMYVSSKKLGLMSATGENAEDVESLFQAILLNRPMIIFKSDFGLVGIR--NNRVECNMSTYEAFQLETANDGNYMLKVCGNKDAYWRTGDDNGIKIDGSAPPQQFILQFDSGTHCAILASNGKYIRGEQNGLMKADSDEINKASLWEF 1870
            M +NG++        +L  + G+VN+A +YLTAE+FGFK+N SA SLK++Q+W + PD  +     F  SHL RYLS+++DG+V+CE+++ G + +F +   P+  G+W  +S  +G +  G EDR+SCF+   SP+  W+  LAIHPQ H+ ++ R+RYV   LQ DE+  D  +PWG D+L+TL   +  +  + S D RYL  DG L  +   ++ Y LE + G      FKD +G+YL  +G  GT+K+ +N   SKDE+F LE S+PQV L A N ++ S++QG+++ ANQ +    E F ++    +KK    +  G YWT+ + + GI+AT+   + +++F+ I     +V +KASN  +V  KK G ++A  +   + E LF   L+NRP+++ +   G V  R  +N+++ N STY+ F L +  DG Y ++  G    +W TG    +  DG    + F+ +F      AI A +GKY+RG  +GL++AD+D     +LWE+
Sbjct:    1 MPTNGLH-------QVLKIQFGLVNDADRYLTAESFGFKVNASAASLKRKQIWVLEPDPGQGTAVLFRSSHLGRYLSAEEDGRVACEMDQPGRDCRFLV--LPQPDGRWVLQSEPHGRFFGGIEDRLSCFATAISPAELWTVHLAIHPQAHLLSVSRRRYVHLCLQEDEMAADGDMPWGVDALVTLIFQS-RRYCLKSYDSRYLRSDGRLVWEPEAHACYTLEFKAGK---LAFKDCDGRYLAPVGPAGTLKAGRNTRPSKDELFDLEQSHPQVVLVAANRRYISVRQGINVSANQDEELGHETFLMQIDQETKKCTFYSSTGGYWTLVT-HGGIQATATQVSANTMFE-IEWHGRRVALKASNGRFVCMKKNGQLAAISDFVGEDE-LFTLKLINRPLLVLRGLDGFVCHRRGSNQLDTNRSTYDVFHL-SFRDGAYQIR--GRGGGFWYTGSHGSVCSDGDL-AEDFLFEFRERGRLAIRALSGKYLRGGASGLLRADADLPVGEALWEY 492
[Close]
BLAST of Fascin vs. TrEMBL
Match: T1E1F2 (Fascin OS=Dendrocoelum lacteum OX=27895 PE=2 SV=1)

HSP 1 Score: 801.586 bits (2069), Expect = 0.000e+0
Identity = 363/502 (72.31%), Postives = 440/502 (87.65%), Query Frame = 2 
Query:  365 MSSNGVNGSSESFNPILTWEMGIVNEAGKYLTAETFGFKINVSATSLKKRQLWTMIPDKTAEYFFIKSHLNRYLSSDKDGKVSCEVEENGVEEQFFIEYCPKGTGKWAFKSVAYGYYLTGNEDRISCFSKSPSWWSARLAIHPQVHMQNMKRQRYVRLQGDELHGDQVIPWGFDSLITLEHSTCGKVAVCSRDHRYLNKDGSLSDKITENSLYGLELRGGANPGFTFKDNEGKYLTLIGSTGTVKSKNKVVSKDEIFTLEISYPQVGLRAHNGKFASIKQGVDLYANQADAEEKEIFQLEYQNSSKKWKIRTCDGKYWTVTSVNSGIKATSGDNNESSLFDIIHLTSGKVLIKASNNMYVSSKKLGLMSATGENAEDVESLFQAILLNRPMIIFKSDFGLVGIRNNRVECNMSTYEAFQLETANDGNYMLKVCGNKDAYWRTGDDNGIKIDGSAPPQQFILQFDSGTHCAILASNGKYIRGEQNGLMKADSDEINKASLWEF 1870
            M+SNGVNGS+    P L WEMGIVN AGK+LTAETFGFKINVSAT+LKK+Q+WT+IPD  +++FFIKSHLN+YLSSDKDGKVSCE+EE G EEQF IEYCPKGTGKW+FKS AYGYY TG+EDRI CFSK+PSWWS RLA+HPQ+HMQNMKRQRYVRLQ  EL GDQ IPWG+DSLITLEHS CG+VA+CSRDHRYL+++G ++++++E++++GLE+RGGA PG  FKD EGKYLTLIG+TGT+KSKNK + KDE+F +EIS+PQVGL+AHNGK+ASIKQG+DLYANQADA EKEIFQ EYQN   +WKIR+ DGKYWTV+SVN+GIKATS   + SS F++  L SGK+L+KASN+M+V+S+KLG+M+A+G+ A+D E+LFQ ILLNRP+IIFKS+FGLVG RN R+ECNMS+YE+F+L++ NDGNY LKV G+KD YW+  DD  IK+D S P QQF++ F SGTHCAILA NG+YIRGEQNGLMKADS+EINKASLWEF
Sbjct:    1 MNSNGVNGSA-MHTPALIWEMGIVNGAGKFLTAETFGFKINVSATTLKKKQIWTIIPDTVSDHFFIKSHLNKYLSSDKDGKVSCEIEECGKEEQFLIEYCPKGTGKWSFKSAAYGYYFTGSEDRIDCFSKTPSWWSVRLAVHPQMHMQNMKRQRYVRLQDSELRGDQTIPWGYDSLITLEHSPCGRVAICSRDHRYLHREGHVTEEMSEDTVFGLEVRGGATPGMAFKDKEGKYLTLIGNTGTLKSKNKAIGKDELFIMEISFPQVGLKAHNGKYASIKQGMDLYANQADAGEKEIFQFEYQNKPGQWKIRSSDGKYWTVSSVNNGIKATSDGRDASSAFNVESLASGKILLKASNDMFVTSRKLGVMTASGDKADDPENLFQLILLNRPLIIFKSEFGLVGTRNGRIECNMSSYESFELQSVNDGNYNLKVRGDKDVYWKVADDGSIKVDASIPAQQFVILFQSGTHCAILAPNGRYIRGEQNGLMKADSEEINKASLWEF 501
[Close]
BLAST of Fascin vs. TrEMBL
Match: A0A267H3R0 (Fascin OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig023083g2 PE=3 SV=1)

HSP 1 Score: 504.212 bits (1297), Expect = 3.626e-169
Identity = 240/486 (49.38%), Postives = 339/486 (69.75%), Query Frame = 2 
Query:  419 WEMGIVNEA-GKYLTAETFGFKINVSATSLKKRQLWTMIPDKTAEYFF-IKSHLNRYLSSDKDGKVSCEVEENGVEEQFFIEYCPKGTGKWAFKSVAYGYYLTGNEDRISCFSKSPSWWSARLAIHPQVHMQNMKRQRYVRLQGDELHGDQVIPWGFDSLITLEHSTCGKVAVCSRDHRYLNKDGSLSDKITENSLYGLELRGGANPGFTFKDNEGKYLTLIGSTGTVKSKNKVVSKDEIFTLEISYPQVGLRAHNGKFASIKQGVDLYANQADAEEKEIFQLEYQNSSKKWKIRTCDGKYWTVTSVNSGIKATSGDNNESSLFDIIHLTSGKVLIKASNNMYVSSKKLGLMSATGENAEDVESLFQAILLNRPMIIFKSDFGLVGIRNNRVECNMSTYEAFQLETANDGNYMLKVCGNKDAYWRTGDDNGIKIDGSAPPQQFILQFDSGTHCAILASNGKYIRGEQNGLMKADSDEINKASLWEF 1870
            W++G+ + A GK+LTAE FGFK+NVSA+SLKKRQ WT++PD   E F  ++SHLNRYLS+DKDG V+   E    EE+F +EY  +G  + A +SV +G+Y +G  D++ CF++SP WW  +LA+HPQVH++N+ R RY+RL   E+ GD+V PWG +SLITL  S  G+VA+ + D  YL++ G LS +++E  L   E   GA PG  FKD+ G+YLT  GS+GT K+KN+ V+KDE+F LE SYPQV ++A NG++AS+KQG DL  NQ++ E  E +QLE+ +S+ KW+ RT D K+W +++V +G+ A+    + ++ F++ HL  G V IK+SN  Y+S+KKLG ++A G      E  FQ +LLNRP+ +F+ DFG VG+RN R+ECN+S+Y+AFQLE AN G Y +K     + YW    D  I   G+A P++FI QF S +  AILA NG Y+RGEQNG ++AD+ EI +A LWE+
Sbjct:    6 WKVGLCSAATGKFLTAEPFGFKLNVSASSLKKRQTWTLVPDAHTESFVALRSHLNRYLSADKDGNVTACAESVDTEERFAVEYSSEGGARLALRSVLHGWYFSGEGDQVRCFARSPVWWKCQLALHPQVHLKNLNRGRYLRLGDGEISGDRVNPWGAESLITLMQSVDGRVAIRASDGSYLSRTGELSAEMSEEVLLSPEFHCGAAPGLAFKDSNGRYLTNTGSSGTTKTKNQNVTKDELFVLEASYPQVAVKAFNGRYASVKQGQDLNVNQSEIEATETYQLEFVSSTGKWRFRTKDDKFWRLSAVANGVNASGDAGDATTQFELEHLAKGFVAIKSSNGYYLSAKKLGAVNAVGAEVR-AEETFQLVLLNRPIAVFRCDFGFVGVRNGRLECNLSSYDAFQLEAANSGFYHIK---GPEGYWIIQGDFSISFKGAA-PEEFIFQFHSRSRVAILAHNGCYVRGEQNGTVRADATEITEACLWEY 486
[Close]
BLAST of Fascin vs. TrEMBL
Match: A0A1I8I4V4 (Fascin OS=Macrostomum lignano OX=282301 PE=3 SV=1)

HSP 1 Score: 501.13 bits (1289), Expect = 7.648e-168
Identity = 242/497 (48.69%), Postives = 341/497 (68.61%), Query Frame = 2 
Query:  419 WEMGIVNEA-GKYLTAETFGFKINVSATSLKKRQLWTMIPDKTAEYFF-IKSHLNRYLSSDKDGKVSCEVEENGVEEQFFIEYCPKGTGKWAFKSVAYGYYLTGNEDRISCFSKSPSWWSARLAIHPQVHMQNMKRQRYVRLQGDELHGDQVIPWGFDSLITLEHSTCGKVAVCSRDHRYLNKDGSLSDKITENSLYGLELRGGANPGFTFKDNEGKYLTLIGSTGTVKSKNKVVSKDEIFTLEISYPQVGLRAHNGKFASIKQGVDLYANQADAEEKEIFQLEYQNSSKKWKIRTCDGKYWTVTSVNSGIKATSGDNNESSLFDIIHLTSGKVLIKASNNMYVSSKKLGLMSATGENAEDVESLFQAILLNRPMIIFKSDFGLVGIRNNRVECNMSTYEAFQLETANDGNYMLK----VCGN-------KDAYWRTGDDNGIKIDGSAPPQQFILQFDSGTHCAILASNGKYIRGEQNGLMKADSDEINKASLWEF 1870
            W++G+ + A GK+LTAE FGFK+NVSA+SLKKRQ WT++PD   E F  ++SHLNRYLS+DKDG V+   E    EE+F +EY  +G  + A +SV +G+Y +G  D++ CF++SP WW  +LA+HPQVH++N+ R RY+RL   E+ GD+V PWG +SLITL  S  G+VA+ + D  YL++ G LS +++E  L   E   GA PG  FKD+ G+YLT  GS+GT K+KN+ V+KDE+F LE SYPQV ++A NG++AS+KQG DL  NQ++ E  E +QLE+ +S+ KW+ RT D K+W +++V +G+ A+    + ++ F++ HL  G V IK+SN  Y+S+KKLG ++A G      E  FQ +LLNRP+ +F+ DFG VG+RN R+ECN+S+Y+AFQLE AN G Y +K     CG         + YW    D  I   G+A P++FI QF S +  AILA NG Y+RGEQNG ++AD+ EI +A LWE+
Sbjct:    6 WKVGLCSAATGKFLTAEPFGFKLNVSASSLKKRQTWTLVPDAHTESFVALRSHLNRYLSADKDGNVTACAESVDTEERFAVEYSSEGGARLALRSVLHGWYFSGEGDQVRCFARSPVWWKCQLALHPQVHLKNLNRGRYLRLGDGEISGDRVNPWGAESLITLMQSVDGRVAIRASDGSYLSRTGELSAEMSEEVLLSPEFHCGAAPGLAFKDSNGRYLTNTGSSGTTKTKNQNVTKDELFVLEASYPQVAVKAFNGRYASVKQGQDLNVNQSEIEATETYQLEFVSSTGKWRFRTKDDKFWRLSAVANGVNASGDAGDATTQFELEHLAKGFVAIKSSNGYYLSAKKLGAVNAVGAEVR-AEETFQLVLLNRPIAVFRCDFGFVGVRNGRLECNLSSYDAFQLEAANSGFYHIKGEPPGCGTSGVGNSGPEGYWIIQGDFSISFKGAA-PEEFIFQFHSRSRVAILAHNGCYVRGEQNGTVRADATEITEACLWEY 500
[Close]
BLAST of Fascin vs. TrEMBL
Match: A0A1I8I1J3 (Fascin OS=Macrostomum lignano OX=282301 PE=3 SV=1)

HSP 1 Score: 499.59 bits (1285), Expect = 3.763e-167
Identity = 241/497 (48.49%), Postives = 341/497 (68.61%), Query Frame = 2 
Query:  419 WEMGIVNEA-GKYLTAETFGFKINVSATSLKKRQLWTMIPDKTAEYFF-IKSHLNRYLSSDKDGKVSCEVEENGVEEQFFIEYCPKGTGKWAFKSVAYGYYLTGNEDRISCFSKSPSWWSARLAIHPQVHMQNMKRQRYVRLQGDELHGDQVIPWGFDSLITLEHSTCGKVAVCSRDHRYLNKDGSLSDKITENSLYGLELRGGANPGFTFKDNEGKYLTLIGSTGTVKSKNKVVSKDEIFTLEISYPQVGLRAHNGKFASIKQGVDLYANQADAEEKEIFQLEYQNSSKKWKIRTCDGKYWTVTSVNSGIKATSGDNNESSLFDIIHLTSGKVLIKASNNMYVSSKKLGLMSATGENAEDVESLFQAILLNRPMIIFKSDFGLVGIRNNRVECNMSTYEAFQLETANDGNYMLK----VCGNK-------DAYWRTGDDNGIKIDGSAPPQQFILQFDSGTHCAILASNGKYIRGEQNGLMKADSDEINKASLWEF 1870
            W++G+ + A GK+LTAE FGFK+NVSA+SLKKRQ WT++PD   E F  ++SHLNRYLS+DKDG V+   E    EE+F +EY  +G  + A +SV +G+Y +G  D++ CF++SP WW  +LA+HPQVH++N+ R RY+RL   E+ GD+V PWG +SLITL  S  G+VA+ + D  YL++ G LS +++E  L   E   GA PG  FKD+ G+YLT  GS+GT K+KN+ V+KDE+F LE SYPQV ++A NG++AS+KQG DL  NQ++ E  E +QLE+ +S+ KW+ RT D K+W +++V +G+ A+    + ++ F++ HL  G V IK+SN  Y+S+KKLG ++A G      E  FQ +LLNRP+ +F+ DFG VG+RN R+ECN+S+Y+AFQLE A+ G Y +K     CG         + YW    D  I   G+A P++FI QF S +  AILA NG Y+RGEQNG ++AD+ EI +A LWE+
Sbjct:    6 WKVGLCSAATGKFLTAEPFGFKLNVSASSLKKRQTWTLVPDAHTESFVALRSHLNRYLSADKDGNVTACAESVDTEERFAVEYSSEGGARLALRSVLHGWYFSGEGDQVRCFARSPVWWKCQLALHPQVHLKNLNRGRYLRLGDGEISGDRVNPWGAESLITLMQSADGRVAIRASDGSYLSRTGELSAEMSEEVLLSPEFHCGAAPGLAFKDSNGRYLTNTGSSGTTKTKNQNVTKDELFVLEASYPQVAVKAFNGRYASVKQGQDLNVNQSEIEATETYQLEFVSSTGKWRFRTKDDKFWRLSAVANGVNASGDAGDATTQFELEHLAKGFVAIKSSNGYYLSAKKLGAVNAVGAEVR-AEETFQLVLLNRPIAVFRCDFGFVGVRNGRLECNLSSYDAFQLEAADSGFYHIKGEPPGCGTSGVGNSGPEGYWIIQGDFSISFKGAA-PEEFIFQFHSRSRVAILAHNGCYVRGEQNGTVRADATEITEACLWEY 500
[Close]
BLAST of Fascin vs. TrEMBL
Match: A0A1I8GT81 (Uncharacterized protein OS=Macrostomum lignano OX=282301 PE=4 SV=1)

HSP 1 Score: 499.975 bits (1286), Expect = 5.578e-167
Identity = 246/514 (47.86%), Postives = 344/514 (66.93%), Query Frame = 2 
Query:  374 NGVNGSSESFNPI-------------LTWEMGIVNEAGKYLTAETFGFKINVSATSLKKRQLWTMIPD-KTAEYFFIKSHLNRYLSSDKDGKVSCEVEENGVEEQFFIEYCPKGTGKWAFKSVAYGYYLTGNEDRISCFSKSPSWWSARLAIHPQVHMQNMKRQRYVRLQGDELHGDQVIPWGFDSLITLEHSTCGKVAVCSRDHRYLNKDGSLSDKITE-NSLYGLELRGGANPGFTFKDNEGKYLTLIGSTGTVKSKNKVVSKDEIFTLEISYPQVGLRAHNGKFASIKQGVDLYANQADAEEKEIFQLEYQNSSKKWKIRTCDGKYWTVTSVNSGIKATSGDNNESSLFDIIHLTSGKVLIKASNNMYVSSKKLGLMSATGENAEDVESLFQAILLNRPMIIFKSDFGLVGIRNNRVECNMSTYEAFQLETANDGNYMLKVCGNKDAYWRTGDDNGIKIDGSAPPQQFILQFDSGTHCAILASNGKYIRGEQNGLMKADSDEINKASLWEF 1870
            NGV GS+    P              L W +G+ N +GK+LTAE FGFK+N S  SLK RQ W ++PD +      +KSHLNR+LS+DKDG VSC  EE G E +F IEY   G  +WA KS  +G Y +G EDR+ CFSK+P WW+ +LA+HPQVH++N+ R RY+RL   E+  D+V PWG +SLITL     G+VA+ + D RYL + G L D++ E  SL+ +++  G  PG  FKD+ G++LT IG+TGT K+KN+ VSKDE+F LE SYPQ+ ++A NG++ASIKQG DL ANQ+D +  E +QLE+  +S KW+ RT D K+W +++V SGI AT    ++S+LF + +   G+V +K SN  Y+S+KKLG ++ATG   +  E  FQ +LLNRP+++F+ DFG VGI+N+R+ECN+ +Y+AF LE ++ G Y ++     + +W    D  I   G   P++F+L+F S +  AI ASNG Y+RGEQNG M+AD+DEI  A LWE+
Sbjct:   20 NGVAGSTNGHGPSKPQQPQAGDPDESLKWRVGLRNASGKFLTAEPFGFKLNASGASLKMRQTWVLVPDPEHPSTVCLKSHLNRFLSADKDGLVSCSSEEAGPETRFIIEYAGDGV-QWALKSAQHGLYFSGEEDRVKCFSKAPVWWTCQLALHPQVHVKNLNRGRYLRLGSGEISADRVNPWGAESLITLMKRD-GRVAIRASDGRYLARGGELLDRLDEAESLFSIQVHCGPCPGLAFKDSAGRFLTNIGATGTSKTKNQTVSKDELFVLEDSYPQIAVKAFNGRYASIKQGQDLNANQSDIDVTETYQLEFHAASGKWRFRTKDDKFWKLSTVGSGISATGDSRDQSTLFAMEYQPKGRVALKCSNGSYLSAKKLGAVNATGSEVKS-EEQFQLVLLNRPIVVFRCDFGFVGIKNSRLECNLVSYDAFNLEVSDSGFYHIR---GSEGFWCVQADGSISFKGER-PEEFLLEFRSRSCVAIQASNGCYVRGEQNGTMRADADEIRAACLWEY 526
[Close]
BLAST of Fascin vs. Ensembl Cavefish
Match: fscn1a (fascin [Source:NCBI gene;Acc:103025781])

HSP 1 Score: 343.969 bits (881), Expect = 2.757e-110
Identity = 202/506 (39.92%), Postives = 310/506 (61.26%), Query Frame = 2 
Query:  380 VNGSSESFNPILTWEMGIVNEAGKYLTAETFGFKINVSATSLKKRQLWTMIPD-KTAEYFFIKSHLNRYLSSDKDGKVSCEVEENGVEEQFFIEYCPKGTGKWAFKSVAYGYYLTGNEDRISCFSKSPSW---WSARLAIHPQVHMQNMKRQRYVRLQG--DELHGDQVIPWGFDSLITLEHSTCGKVAVCSRDHRYLNKDGSLSDKITENSLYGLELRGGANPGFTFKDNEGKYLTLIGSTGTVKS-KNKVVSKDEIFTLEISYPQVGLRAHNGKFASIKQGVDLYANQADAEEKEIFQLEYQNSSKKWKIRTCDGKYWTVTSVNSGIKATSGDNNESSLFDIIHLTSGKVLIKASNNMYVSSKKLGLMSATGENAEDVESLFQAILLNRPMIIFKSDFGLVGIR--NNRVECNMSTYEAFQLETANDGNYMLKVCGNKDAYWRTGDDNGIKIDGSAPPQQFILQFDSGTHCAILASNGKYIRGEQNGLMKADSDEINKASLWEF 1870
             NGSS + + +L  + G++N   KYLTAETFGFKIN SATS+KK+Q+WT+  +   +  FF+KSHL RY+++DKDG V+ + EE G + +F I       G+W+ +S  +  YL G EDRI+CF+++ S    WS  +A+HPQV++ +M R+RY  L    DE+  D+ +PWG DSLITL      +  + + D+R+L  DG+L+ K  + + Y LE R G      F+D  GKYL   G +GT+KS K+  V KDE+F LE S+PQV L A N +  S +QG+DL ANQ +  ++E FQ+E    +KK   RTC GKYWT+T+ N G++ T+   + +  FD I     K+ ++A+N  YV++KK G ++AT ++A + E  F   L+NRP+I+ + + G +G R     ++ N S+Y+ F L    DG Y L+    K  YW  G ++ +      P   F L+F      AI ++ GKY+RG+  G++KA++D+++ +++WE+
Sbjct:    3 TNGSSSNSSDMLKIQFGLINCGNKYLTAETFGFKINASATSMKKKQIWTLEQNGDDSNMFFLKSHLGRYIAADKDGNVTGDSEEPGEDCRFII--TAHDDGRWSLQSEPHKRYLGGTEDRITCFAQTISIAEKWSVHIAMHPQVNIFSMTRKRYAHLSSKEDEIAIDRDVPWGVDSLITLVFQD-QRYHLQTSDNRFLKNDGALAQKADKTTGYTLEFRSGK---VAFRDCAGKYLAPSGPSGTMKSGKSSKVGKDELFVLEQSHPQVVLTAANDRNVSTRQGMDLSANQDEEGDQETFQMEISKETKKCAFRTCSGKYWTLTA-NGGLQCTASTKSANCHFD-IEWRGKKITLRAANGKYVAAKKNGQLAATIDSAGESEE-FLMKLINRPLIVLRGEHGFIGCRKVTGTLDSNRSSYDVFGL-AFRDGAYSLQDSTGK--YWMVGSESSVVSSSDTPV-DFFLEFCDYNKVAIKSTEGKYLRGDHAGVLKANADDLDSSTMWEY 495
[Close]
BLAST of Fascin vs. Ensembl Cavefish
Match: fscn2b (fascin-2 [Source:NCBI gene;Acc:103025956])

HSP 1 Score: 333.954 bits (855), Expect = 1.978e-106
Identity = 193/498 (38.76%), Postives = 297/498 (59.64%), Query Frame = 2 
Query:  404 NPILTWEMGIVNEAGKYLTAETFGFKINVSATSLKKRQLWTMIPD-KTAEYFFIKSHLNRYLSSDKDGKVSCEVEENGVEEQFFIEYCPKGTGKWAFKSVAYGYYLTGNEDRISCFSKS---PSWWSARLAIHPQVHMQNMKRQRYVRLQGDE--LHGDQVIPWGFDSLITLEHSTCGKVAVCSRDHRYLNKDGSLSDKITENSLYGLELRGGANPGFTFKDNEGKYLTLIGSTGTVKS-KNKVVSKDEIFTLEISYPQVGLRAHNGKFASIKQGVDLYANQADAEEKEIFQLEYQNSSKKWKIRTCDGKYWTVTSVNSGIKATSGDNNESSLFDIIHLTSGKVLIKASNNMYVSSKKLGLMSATGENAEDVESLFQAILLNRPMIIFKSDFGLVGIR--NNRVECNMSTYEAFQLETANDGNYMLKVCGNKDAYWRTGDDNGIKIDGSAPPQQFILQFDSGTHCAILASNGKYIRGEQNGLMKADSDEINKASLWEF 1870
            N  L  + G++N   +YLTAE FGFK+N SA SLKK+Q+WT+  D K  +  +++SHL RYL+SDKDGKVSCE E    + +F I    +  G+WA +S  +  +  G++D +SCF+++      W+  LA+HPQ ++ ++ R+RY  L   E  +  D  IPWG D+L+TL +   GK  + + D R+L+ DG LS +    + Y LEL+ G      FKD EGKYL+ +G TGT++S +     KDE+F LE S+PQV  +A N +F SI+QGV + ANQ D  + E FQ+E    SKK K RT +G YWT+ + + GI++T+ +   +++FDI+ L   +V ++A+N  YV +KK G ++A  ++  + E +    L+NRP++I + + G V     +N ++ N S Y+ F L   +DG Y +K  G +  +W       +  DG   P+ F  +F      AI   NGKY+RG+Q G +K+D +  + +SLWE+
Sbjct:    6 NKALKLQFGLINFESRYLTAEAFGFKVNASAPSLKKKQIWTLEQDEKDGQVVYLRSHLGRYLASDKDGKVSCEAESQESDCRFLI--VAQSDGRWALQSEPHLRFFGGSKDYLSCFAQTIGEAELWAMHLALHPQANLLSVARKRYAHLSAPEGEIAVDSNIPWGVDALLTLVYVD-GKYCLKTCDSRFLSSDGKLSFENGRGTGYTLELKSGK---LAFKDCEGKYLSPMGPTGTLRSGRCSKPGKDELFDLEESHPQVVFQAANNRFVSIRQGVSVSANQEDETDMETFQMEIDKDSKKCKFRTNEGNYWTLVA-HGGIQSTAREAGANTMFDIVWLGR-RVALRANNGKYVCTKKNGQLAAVSDSVGEDEQMILK-LINRPILILRGENGYVCHHKNSNTLDANRSVYDIFTL-GFSDGAYHIKGAGGR--FWYVSSSGMVCSDGDT-PEDFCFEFLEHGRIAIRGKNGKYLRGDQGGTLKSDGENADGSSLWEY 490
[Close]
BLAST of Fascin vs. Ensembl Cavefish
Match: fscn2a (fascin-2-like [Source:NCBI gene;Acc:103030006])

HSP 1 Score: 329.331 bits (843), Expect = 1.128e-104
Identity = 197/506 (38.93%), Postives = 295/506 (58.30%), Query Frame = 2 
Query:  380 VNGSSESFNPILTWEMGIVNEAGKYLTAETFGFKINVSATSLKKRQLWTM-IPDKTAEYFFIKSHLNRYLSSDKDGKVSCEVEENGVEEQFFIEYCPKGTGKWAFKSVAYGYYLTGNEDRISCFSKS---PSWWSARLAIHPQVHMQNMKRQRYVRLQG--DELHGDQVIPWGFDSLITLEHSTCGKVAVCSRDHRYLNKDGSLSDKITENSLYGLELRGGANPGFTFKDNEGKYLTLIGSTGTVKS-KNKVVSKDEIFTLEISYPQVGLRAHNGKFASIKQGVDLYANQADAEEKEIFQLEYQNSSKKWKIRTCDGKYWTVTSVNSGIKATSGDNNESSLFDIIHLTSGKVLIKASNNMYVSSKKLGLMSATGENAEDVESLFQAILLNRPMIIFKSDFGLVGIR--NNRVECNMSTYEAFQLETANDGNYMLKVCGNKDAYWRTGDDNGIKIDGSAPPQQFILQFDSGTHCAILASNGKYIRGEQNGLMKADSDEINKASLWEF 1870
             NG+S++    L  + G++N   +YLTAETFGFK+N S +S+KK+Q+WT+   D+ ++  F++SHL RY+ +DKDGKVSC  E    E +F I    +  G+WA +S  Y  Y  G+ D +SCF+++      W+  +A+HPQ ++ ++ R+RY  L     E+  D  IPWG DSL+TL +   GK ++ + D+R+L+ DG L       + + LELR G      FKD+EGKYL  +G TGT+KS +     KDE+F LE S+PQV  +A N +F S++QGV + ANQ    + E FQ+E    +KK   RT  G YWT+ S + GI++T+ D   +++F I  L   +V +KASN  YV +KK G +SA  +   D E LF   L+NRP++I + + G V     +N ++ N S Y+ F L   +DG Y +K    K  +W     + +  D S  P+ F L+F       I   NGKY+RG+Q G +K D+  ++  SLWE+
Sbjct:    3 TNGTSKA----LKLQFGLINHENRYLTAETFGFKVNASGSSMKKKQIWTLEQDDQDSQVVFLRSHLGRYMGADKDGKVSCAAEVPDSECRFLI--VAQSDGRWALQSEPYQRYFGGSADYLSCFAQAIGEAELWAVHMALHPQANLLSVARKRYAHLSAPDSEISVDSNIPWGVDSLVTLVYMD-GKYSLKTCDNRFLSNDGKLVKDYRPQAGFTLELRSGK---LAFKDHEGKYLAPMGPTGTLKSGRCTKPGKDELFDLEESHPQVVFQAANKRFVSVRQGVSISANQDVETDMETFQMEIDKETKKCMFRTNAGNYWTLVS-HGGIQSTATDIEVNTMFQIEWLGR-RVALKASNGKYVCTKKNGQLSAVSDGVGDDE-LFLLKLINRPILILRGENGFVCHHKNSNTLDANRSVYDIFSL-LYSDGAYHIKSANGK--FWYMSGSSLVCSD-SDKPEDFFLEFPEHGRVGIKGINGKYLRGDQGGTLKCDAAGLDLPSLWEY 491
[Close]
BLAST of Fascin vs. Ensembl Cavefish
Match: fscn1b (fascin actin-bundling protein 1b [Source:ZFIN;Acc:ZDB-GENE-120507-1])

HSP 1 Score: 321.627 bits (823), Expect = 8.813e-102
Identity = 185/494 (37.45%), Postives = 283/494 (57.29%), Query Frame = 2 
Query:  413 LTWEMGIVNEAGKYLTAETFGFKINVSATSLKKRQLWTM--IPDKTAEYFFIKSHLNRYLSSDKDGKVSCEVEENGVEEQFFIEYCPKGTGKWAFKSVAYGYYLTGNEDRISCFSKSPSWWSARLAIHPQVHMQNMKRQRYVRLQGDELHGDQVIPWGFDSLITLEHSTCGKVAVCSRDHRYLNKDGSL--SDKITENSLYGLELRGGANPGFTFKDNEGKYLTLIGSTGTVKS-KNKVVSKDEIFTLEISYPQVGLRAHNGKFASIKQGVDLYANQADAEEKEIFQLEYQNSSKKWKIRTCDGKYWTVTSVNSGIKATSGDNNESSLFDIIHLTSGKVLIKASNNMYVSSKKLGLMSATGENAEDVESLFQAILLNRPMIIFKSDFGLVGIRNN---RVECNMSTYEAFQLETANDGNYMLKVCGNKDAYWRTGDDNGIKIDGSAPPQQFILQFDSGTHCAILASNGKYIRGEQNGLMKADSDEINKASLWEF 1870
            L   +G++N   KYLTAE+FGF IN SA S+KK+Q+WT+    D  +    ++SHL RYL+ DKDG V+ + E    + +F +       G+WA +S A+  YL G EDR++C +   + WS  LA+HPQV++ ++ R+RY  ++G +L  D+  PWG D+L+TL ++   +  + + D R+L   G L     +   + + LE R GA    TF+D+ G  L   G TG +K+ K+    KDE+F +E S  QV L A NG+  S++QGVDL ANQ +   +E+FQ+E +   K+   R   GKYW++T  +  I+ T+   + S  FD +     KV +KASN  Y+++KK G ++A+ ++A +   LF   L+NRP+I+   + G +G R      ++CN S+Y+ FQLE  ND  Y LK    K  YW T + +G  +  SA P  F  +F      AI    G Y++G+  G++KA +  I  ASLWE+
Sbjct:   11 LVVRLGLINAENKYLTAESFGFSINASAASMKKKQVWTLEHAGDADSSSVLLRSHLGRYLACDKDGVVTADRERPEADCRFAV--IANDDGRWALRSEAHSRYLGGAEDRVACVANPGTMWSVHLAVHPQVNIYSVARKRYAGVRGGQLAADRDAPWGVDALLTLVYAE-RRYHLQTHDGRFLGASGQLVAGPPVAAATGFTLEFRAGA---VTFRDSTGANLAPSGPTGALKAGKSARSGKDELFVMERSRAQVVLTASNGRNVSMRQGVDLSANQDEESNQEVFQMEMEKEKKRCSFRCYSGKYWSLTP-SGAIQCTASSKSASCFFD-LEWKDSKVTLKASNGKYLTAKKNGQLTASVDSAGE---LFVLKLINRPLIVLLGEHGFIGCRKQGTGTLDCNRSSYDVFQLEY-NDNTYSLKDSTGK--YW-TAEADGTIVSSSATPVYFHFEFCDYNKVAIKTQEGLYLKGDHAGVLKAKAQGIENASLWEY 489
[Close]
BLAST of Fascin vs. Ensembl Nematostella
Match: EDO44834 (Fascin [Source:UniProtKB/TrEMBL;Acc:A7RUD3])

HSP 1 Score: 295.434 bits (755), Expect = 3.715e-92
Identity = 179/498 (35.94%), Postives = 271/498 (54.42%), Query Frame = 2 
Query:  419 WEMGIVNE-AGKYLTAETFGFKINVSATSLKKRQLWTMIPDKTAEYFFIKSHLNRYLSSDKDGKVSCEVEENGVEEQFFIEYCPKGTGKWAFKSVAYGYYLTGNEDRISCFSK--SPSWWSARLAIHPQVHMQNMKRQRYVRL--QGDELHGDQVIPWGFDSLITLEHSTCGKVAVCSRDHRYLNKDGSLSDKITENSLYGLELRGGANPGFTFKDNEGKYLTLIGSTGTVKSKNKVVSKDEIFTLEISYPQVGLRAHNGKFASIKQGVDLYANQADAEEKEIFQLEYQNSSKKWKIRTCDGKYWTVTSVNSGIKATSGDNNESSLFDIIHLTSGKVLIKASNNMYVSSKKLG-LMSATGENAEDVESLFQAILLNRPMIIFKSDFGLVGIR--NNRVECNMSTYEAFQLETANDGNYM-----LKVCGNKDAYWRTGDDNGIKIDGSA-PPQQFILQFDSGTHCAILASNGKYIRGEQNGLMKADSDEINKASLWEF 1870
            W +G++N+ + KYLTAETFGFK+N    SL+K+Q W++      E  ++KSHL RYL++D  G + CE EE     +F +E      GKWA KSV +G Y   N D++ C +K      W+  LA+HPQ++++++ R+RY  L  + +++   ++IPWG D+ ITL+ S  G+  + + + +Y++  G L D+  ++  + +E          F+D++GKYLT +G TG ++SK +   KDE+F LE S+PQV    H  K  SIKQ  DL ANQ D  + EIFQLE+    K   +   +G YW     N  + AT       + F  +   + +V  KA   MY++S K G L+  T E  E     F   ++NRP++I K +FG +G +   NR+ECN + Y+ F LE     +        K+   K  YWR   D  I + G A     F +  +   +  I A NG Y+RG+QNG+  A+   I K SLWE+
Sbjct:    7 WNIGLMNDNSSKYLTAETFGFKLNSDGVSLRKKQTWSL-EQVDGEAIYLKSHLGRYLTADPKGNLCCEAEERESNAKFTVEI---KDGKWALKSV-HGAYFGANGDQLKCVAKIGKTELWTVHLAMHPQINLKSVLRKRYAHLDEEDNDVKVSELIPWGADATITLKFSG-GRYFLVTSNGKYVSASGDLQDEPNDDCSFSVEFH---QTSIAFRDHKGKYLTAVG-TGKLQSKKETAGKDELFQLEDSHPQVSFIGHTNKRVSIKQHTDLRANQMDMGDTEIFQLEFSEDGKTVSLLGNNGMYWV---ANGPVSATEKTITPKAQF-TMEYHNNQVAFKAHTGMYLTSNKQGQLLDGTPELEE--AGKFSMEIVNRPLLILKGEFGFIGCKTSTNRLECNRAAYDVFTLEVEEAESEEERGTWYKIGSEKGKYWRVEGDGSISVSGEANSADLFEIFLERRNYLCIKAKNGAYLRGQQNGVFNANGKSIAKDSLWEY 488
[Close]
BLAST of Fascin vs. Ensembl Medaka
Match: ENSORLT00000012063.2 (fascin [Source:NCBI gene;Acc:101170402])

HSP 1 Score: 351.288 bits (900), Expect = 4.849e-113
Identity = 210/513 (40.94%), Postives = 306/513 (59.65%), Query Frame = 2 
Query:  365 MSSNGVNGSSESFNPILTWEMGIVNEAGKYLTAETFGFKINVSATSLKKRQLWTMIPDKTAE---YFFIKSHLNRYLSSDKDGKVSCEVEENGVEEQFFIEYCPKGTGKWAFKSVAYGYYLTGNEDRISCFSKSPS---WWSARLAIHPQVHMQNMKRQRYVRLQGD-ELHGDQVIPWGFDSLITLEHSTCGKVAVCSRDHRYLNKDGSLSDKITENSLYGLELRGGANPGFTFKDNEGKYLTLIGSTGTVKS-KNKVVSKDEIFTLEISYPQVGLRAHNGKFASIKQGVDLYANQADAEEKEIFQLEYQNSSKKWKIRTCDGKYWTVTSVNSGIKATSGDNNESSLFDIIHLTSGKVLIKASNNMYVSSKKLGLMSATGENAEDVESLFQAILLNRPMIIFKSDFGLVGIRN---NRVECNMSTYEAFQLETANDGNYMLKVCGNKDAYWRTGDDNGIKIDGSAPPQQFILQFDSGTHCAILASNGKYIRGEQNGLMKADSDEINKASLWEF 1870
            MSSN   G       +L   +G++N AGKYLTAE FGFKIN SA+SLKK+Q WT+  ++T E     F+ SHL RYL++DKDG V+ + E  G + +F I       G+W+ +S  +G +L G+EDRI+CF++S S    WS  LA+HPQV++ +  R+RY  L    E+  D+  PWG DSL+TL +    +  + + D+R+L  DGSLS K  +++ Y LE R G      F+D  G+YL   G +GT+KS +     KDE+F LE S  QV L A N +  S +QG+DL ANQ +  ++E+FQLE     +K   +T  GKYWT+T V  G++ T+   + +S FD+     G+V I+A+N  YV++KK G ++AT +NA + E  F   L+NRP+I+ + + G +G R      ++ N ++Y+ FQLE  N G Y  K    K  YW  GDD  I +  S+ P QF+L+F      AI    GKY++G+  G +KA +D ++ ASLWE+
Sbjct:    1 MSSNSAEGD------MLQIPLGLINGAGKYLTAEMFGFKINASASSLKKKQTWTL--EQTGEDGSVVFLLSHLGRYLATDKDGNVTADSETRGRDCRFVI--TAHEDGRWSLQSEPHGRFLGGSEDRITCFAQSASPTERWSVHLAVHPQVNLYSFARKRYAHLSAPGEVAIDRDFPWGVDSLVTLVYRD-QRYHLETSDNRFLRNDGSLSTKTDKDTGYMLEFRSGK---VLFRDCNGRYLAPSGPSGTMKSGRGSRGGKDELFNLERSLAQVVLTAGNERNVSTRQGMDLSANQDEEGDQEVFQLEMSRDDRKCAFKTAAGKYWTLT-VTGGLQCTASTKSANSYFDLA-WRDGRVCIRAANGKYVTAKKNGQLAATVDNAGEAEQ-FLMKLINRPIIVLRGEHGFIGARKPGLPTLDSNRASYDVFQLEFHN-GAYSFKDSQGK--YWCIGDDTAI-VCNSSTPVQFLLEFCDPNKMAIRVVGGKYLKGDHAGALKASADSLDSASLWEY 492
[Close]
BLAST of Fascin vs. Ensembl Medaka
Match: fscn1a (fascin actin-bundling protein 1 [Source:NCBI gene;Acc:101171083])

HSP 1 Score: 340.117 bits (871), Expect = 9.006e-109
Identity = 201/515 (39.03%), Postives = 313/515 (60.78%), Query Frame = 2 
Query:  365 MSSNGV-NGSSESFNPILTWEMGIVNEAGKYLTAETFGFKINVSATSLKKRQLWTMIP---DKTAEYFFIKSHLNRYLSSDKDGKVSCEVEENGVEEQFFIEYCPKGTGKWAFKSVAYGYYLTGNEDRISCFSKSPSW---WSARLAIHPQVHMQNMKRQRYVRLQG--DELHGDQVIPWGFDSLITLEHSTCGKVAVCSRDHRYLNKDGSLSDKITENSLYGLELRGGANPGFTFKDNEGKYLTLIGSTGTVKS-KNKVVSKDEIFTLEISYPQVGLRAHNGKFASIKQGVDLYANQADAEEKEIFQLEYQNSSKKWKIRTCDGKYWTVTSVNSGIKATSGDNNESSLFDIIHLTSGKVLIKASNNMYVSSKKLGLMSATGENAEDVESLFQAILLNRPMIIFKSDFGLVGIR--NNRVECNMSTYEAFQLETANDGNYMLKVCGNKDAYWRTGDDNGIKIDGSAPPQQFILQFDSGTHCAIL-ASNGKYIRGEQNGLMKADSDEINKASLWEF 1870
            M++NG  NG+S+    +L  + G++N   KYLTAETFGFKIN SATS+KK+Q+WT+     + + + F +KSHL RY+++DKDG V+ + E  G E +F I       G+W+ +S A+G YL G EDRI CF+++ S    WS  +A+HPQV++ ++ R+RY  L    DE+  D+ +PWG DS+ITL      +  + + D+R+L  DG+L       + Y LE R G      F+D  G+YL   G +GT+KS K+  V KDE+F LE S+PQV L A N +  S +QG+DL ANQ +  ++E+FQ+E    ++K   RT  GKYWT+T+ N G++ T+   + +  FD I     ++ ++A+N  YV++KK G ++AT + A + E  F   L+NRP I+ + + G +G R     ++ N STY+ F L+ + DG Y L+    K  YW  G+++ + +  S  P  F  +F      A+  A++GKY+RG+  G++KA++D++  A+LWE+
Sbjct:    1 MTANGAANGTSD----MLQIQFGLINCGNKYLTAETFGFKINASATSMKKKQIWTLEQSGDESSGDVFLLKSHLGRYIAADKDGNVTGDSENPGPECRFVI--TAHDDGRWSLQSEAHGRYLGGTEDRILCFAQTVSVAEKWSVHIAMHPQVNLFSLTRKRYAHLSDKVDEIAIDRDVPWGVDSMITLVFWE-QRYHLQTSDNRFLRNDGALVATTDRATGYTLEFRSGK---VAFRDCSGRYLAPSGPSGTMKSGKSARVGKDELFVLEQSHPQVVLTAGNERNVSTRQGMDLSANQDEEGDQEVFQVEICRENRKCAFRTAAGKYWTLTA-NGGLQCTASTKSANCYFD-IEWRGKRLTLQAANGKYVAAKKNGQLAATNDTAGESEE-FIMKLINRPFIVLRGEHGFIGCRKVTGTLDSNRSTYDYFTLQFS-DGAYNLQDSTGK--YWMVGNEHSV-VSSSDTPVDFFFEFCDYNKLAVRHAADGKYLRGDHAGVLKANADDLESATLWEY 498
[Close]
BLAST of Fascin vs. Ensembl Medaka
Match: fscn2a (fascin-2-like [Source:NCBI gene;Acc:101170272])

HSP 1 Score: 332.798 bits (852), Expect = 5.339e-106
Identity = 198/511 (38.75%), Postives = 294/511 (57.53%), Query Frame = 2 
Query:  365 MSSNGVNGSSESFNPILTWEMGIVNEAGKYLTAETFGFKINVSATSLKKRQLWTMIPD-KTAEYFFIKSHLNRYLSSDKDGKVSCEVEENGVEEQFFIEYCPKGTGKWAFKSVAYGYYLTGNEDRISCFSK---SPSWWSARLAIHPQVHMQNMKRQRYVRLQGD--ELHGDQVIPWGFDSLITLEHSTCGKVAVCSRDHRYLNKDGSLSDKITENSLYGLELRGGANPGFTFKDNEGKYLTLIGSTGTVKS-KNKVVSKDEIFTLEISYPQVGLRAHNGKFASIKQGVDLYANQADAEEKEIFQLEYQNSSKKWKIRTCDGKYWTVTSVNSGIKATSGDNNESSLFDIIHLTSGKVLIKASNNMYVSSKKLGLMSATGENAEDVESLFQAILLNRPMIIFKSDFGLVGIR--NNRVECNMSTYEAFQLETANDGNYMLKVCGNKDAYWRTGDDNGIKIDGSAPPQQFILQFDSGTHCAILASNGKYIRGEQNGLMKADSDEINKASLWEF 1870
            M +NG+N +       L  + G++N   +YLTAE FGFK+N S TS+KK+Q+WT+  D +  +  F++SHL RYL++DKDGK++C  E+   E +F I   P+  G+WA +S  Y  Y  G+ D +SCF++       W+  LA+HPQ  + ++ R+RY  L     E+  D  IPWG DSL+TL +   GK ++ + D R+L+ DG L  + +  + + LEL+ G      FKD +GKYL  +G TGT++S +     KDE+F LE S+PQV  +A N +F S+KQGV + ANQ    + E FQ+E    SKK   RT  G YWT+ + +  I++T+ +   +++FD I     +V +KASN  YV +KK G +SA  E   D E LF   L+NRPM+I + + G V     +N ++ N S Y+ F L   NDG Y++K    K  +W     NG+        + F L+F      AI  SNGKY+RG+Q G +  D   ++ +SLWE+
Sbjct:    1 MPTNGINQA-------LKLQFGLINYENRYLTAEAFGFKVNASGTSMKKKQIWTLEQDEQDGQVVFLRSHLGRYLAADKDGKITCGAEKPDPECRFLI--VPQSDGRWALQSEPYLRYFGGSADYLSCFAQVIGEQELWAVHLALHPQASLLSVARKRYAHLSASDGEISVDSNIPWGVDSLVTLVYLD-GKYSLKTCDSRFLSNDGKLVKENSNTTCFTLELKSGK---LAFKDCDGKYLAPLGPTGTLRSGRCSKPGKDELFDLEESHPQVVFQAANKRFVSVKQGVSISANQDVETDMETFQMEIDKESKKALFRTNGGSYWTLVT-HGEIQSTAKEVEINTMFD-IEWRGQRVALKASNGKYVCTKKNGQLSAISETVGDDE-LFLMKLINRPMLILRGENGFVCHHKNSNTLDANRSVYDIFSL-IFNDGAYIIKSVNGK--FWYV-SSNGLVCSDGEKSENFFLEFLEHGRVAIKGSNGKYLRGDQGGTLMCDGASVDVSSLWEY 491
[Close]
BLAST of Fascin vs. Ensembl Medaka
Match: fscn2b (fascin actin-bundling protein 2, retinal [Source:NCBI gene;Acc:101155304])

HSP 1 Score: 313.923 bits (803), Expect = 8.766e-99
Identity = 183/498 (36.75%), Postives = 290/498 (58.23%), Query Frame = 2 
Query:  404 NPILTWEMGIVNEAGKYLTAETFGFKINVSATSLKKRQLWTMIPD-KTAEYFFIKSHLNRYLSSDKDGKVSCEVEENGVEEQFFIEYCPKGTGKWAFKSVAYGYYLTGNEDRISCFSKS---PSWWSARLAIHPQVHMQNMKRQRYVRL--QGDELHGDQVIPWGFDSLITLEHSTCGKVAVCSRDHRYLNKDGSLSDKITENSLYGLELRGGANPGFTFKDNEGKYLTLIGSTGTVKS-KNKVVSKDEIFTLEISYPQVGLRAHNGKFASIKQGVDLYANQADAEEKEIFQLEYQNSSKKWKIRTCDGKYWTVTSVNSGIKATSGDNNESSLFDIIHLTSGKVLIKASNNMYVSSKKLGLMSATGENAEDVESLFQAILLNRPMIIFKSDFGLVGIR--NNRVECNMSTYEAFQLETANDGNYMLKVCGNKDAYWRTGDDNGIKIDGSAPPQQFILQFDSGTHCAILASNGKYIRGEQNGLMKADSDEINKASLWEF 1870
            N  L  + G++N  G+YLTAE FGFK+N SA SLKK+Q+WT+  D +  +  +++SHL RYL+SDKDGKVSCE +    + +F I   P+  G+WA +S  Y  +  G+ D +SCF+++      W+  LA+HPQ ++ ++ R+RY RL  +  E+  D  IPWG  +L+T+ +   G+  + + D R+L+ DG L  +    + Y LEL+ G      FKD EGKYL+ +G TGT++S +     KDE+F L  S+PQV L A NG++ SI+QGV L ANQ D  + E FQ+E    +KK   R+  G YW + + +  I++ + + + +++F  +     KV +KASN  Y+ +KK G + A  ++  + E L    L+NRPM+I + + G +     +N ++ + S Y+ F L+ +N G+Y +K  G    +W       +  DG   P+ F L+       AI   NG+Y+RG+Q G +K D   ++ ++LWE+
Sbjct:    6 NHPLKLQFGLINHEGRYLTAEAFGFKLNASAPSLKKKQIWTLEQDLQDTQVVYLRSHLGRYLASDKDGKVSCEADGQNSDCRFLI--VPQSDGRWALQSEQYLRFFGGSRDYLSCFAQAITDAELWAMHLALHPQANLLSVARKRYARLSMEDGEIAVDLNIPWGVGALLTIVYVD-GRYCLKTSDSRFLSNDGKLLTQTERTTQYTLELKCGK---LAFKDCEGKYLSPMGPTGTLRSGRCSKPGKDELFDLVESHPQVVLIAANGRYVSIRQGVSLAANQEDETDMETFQMEIDKDTKKCTFRSSLGNYWALVA-HGDIQSNATEVSANTMFS-LEWFGHKVALKASNGKYICTKKNGQLLAVSDSIGEDEQL-TLKLINRPMLILRGENGFICHHKSSNTLDASRSVYDIFTLQFSN-GSYHIK--GVDGRFWYVNSAGLVCSDGEV-PEDFTLELLEHGRLAIRGRNGRYLRGDQGGTLKGDGLGVSSSALWEY 490
[Close]
BLAST of Fascin vs. Ensembl Medaka
Match: fscn2b (fascin actin-bundling protein 2, retinal [Source:NCBI gene;Acc:101155304])

HSP 1 Score: 313.923 bits (803), Expect = 8.766e-99
Identity = 183/498 (36.75%), Postives = 290/498 (58.23%), Query Frame = 2 
Query:  404 NPILTWEMGIVNEAGKYLTAETFGFKINVSATSLKKRQLWTMIPD-KTAEYFFIKSHLNRYLSSDKDGKVSCEVEENGVEEQFFIEYCPKGTGKWAFKSVAYGYYLTGNEDRISCFSKS---PSWWSARLAIHPQVHMQNMKRQRYVRL--QGDELHGDQVIPWGFDSLITLEHSTCGKVAVCSRDHRYLNKDGSLSDKITENSLYGLELRGGANPGFTFKDNEGKYLTLIGSTGTVKS-KNKVVSKDEIFTLEISYPQVGLRAHNGKFASIKQGVDLYANQADAEEKEIFQLEYQNSSKKWKIRTCDGKYWTVTSVNSGIKATSGDNNESSLFDIIHLTSGKVLIKASNNMYVSSKKLGLMSATGENAEDVESLFQAILLNRPMIIFKSDFGLVGIR--NNRVECNMSTYEAFQLETANDGNYMLKVCGNKDAYWRTGDDNGIKIDGSAPPQQFILQFDSGTHCAILASNGKYIRGEQNGLMKADSDEINKASLWEF 1870
            N  L  + G++N  G+YLTAE FGFK+N SA SLKK+Q+WT+  D +  +  +++SHL RYL+SDKDGKVSCE +    + +F I   P+  G+WA +S  Y  +  G+ D +SCF+++      W+  LA+HPQ ++ ++ R+RY RL  +  E+  D  IPWG  +L+T+ +   G+  + + D R+L+ DG L  +    + Y LEL+ G      FKD EGKYL+ +G TGT++S +     KDE+F L  S+PQV L A NG++ SI+QGV L ANQ D  + E FQ+E    +KK   R+  G YW + + +  I++ + + + +++F  +     KV +KASN  Y+ +KK G + A  ++  + E L    L+NRPM+I + + G +     +N ++ + S Y+ F L+ +N G+Y +K  G    +W       +  DG   P+ F L+       AI   NG+Y+RG+Q G +K D   ++ ++LWE+
Sbjct:    6 NHPLKLQFGLINHEGRYLTAEAFGFKLNASAPSLKKKQIWTLEQDLQDTQVVYLRSHLGRYLASDKDGKVSCEADGQNSDCRFLI--VPQSDGRWALQSEQYLRFFGGSRDYLSCFAQAITDAELWAMHLALHPQANLLSVARKRYARLSMEDGEIAVDLNIPWGVGALLTIVYVD-GRYCLKTSDSRFLSNDGKLLTQTERTTQYTLELKCGK---LAFKDCEGKYLSPMGPTGTLRSGRCSKPGKDELFDLVESHPQVVLIAANGRYVSIRQGVSLAANQEDETDMETFQMEIDKDTKKCTFRSSLGNYWALVA-HGDIQSNATEVSANTMFS-LEWFGHKVALKASNGKYICTKKNGQLLAVSDSIGEDEQL-TLKLINRPMLILRGENGFICHHKSSNTLDASRSVYDIFTLQFSN-GSYHIK--GVDGRFWYVNSAGLVCSDGEV-PEDFTLELLEHGRLAIRGRNGRYLRGDQGGTLKGDGLGVSSSALWEY 490
[Close]
BLAST of Fascin vs. Planmine SMEST
Match: SMESG000037971.1 (SMESG000037971.1)

HSP 1 Score: 1045.8 bits (2703), Expect = 0.000e+0
Identity = 502/502 (100.00%), Postives = 502/502 (100.00%), Query Frame = 2 
Query:  365 MSSNGVNGSSESFNPILTWEMGIVNEAGKYLTAETFGFKINVSATSLKKRQLWTMIPDKTAEYFFIKSHLNRYLSSDKDGKVSCEVEENGVEEQFFIEYCPKGTGKWAFKSVAYGYYLTGNEDRISCFSKSPSWWSARLAIHPQVHMQNMKRQRYVRLQGDELHGDQVIPWGFDSLITLEHSTCGKVAVCSRDHRYLNKDGSLSDKITENSLYGLELRGGANPGFTFKDNEGKYLTLIGSTGTVKSKNKVVSKDEIFTLEISYPQVGLRAHNGKFASIKQGVDLYANQADAEEKEIFQLEYQNSSKKWKIRTCDGKYWTVTSVNSGIKATSGDNNESSLFDIIHLTSGKVLIKASNNMYVSSKKLGLMSATGENAEDVESLFQAILLNRPMIIFKSDFGLVGIRNNRVECNMSTYEAFQLETANDGNYMLKVCGNKDAYWRTGDDNGIKIDGSAPPQQFILQFDSGTHCAILASNGKYIRGEQNGLMKADSDEINKASLWEF 1870
            MSSNGVNGSSESFNPILTWEMGIVNEAGKYLTAETFGFKINVSATSLKKRQLWTMIPDKTAEYFFIKSHLNRYLSSDKDGKVSCEVEENGVEEQFFIEYCPKGTGKWAFKSVAYGYYLTGNEDRISCFSKSPSWWSARLAIHPQVHMQNMKRQRYVRLQGDELHGDQVIPWGFDSLITLEHSTCGKVAVCSRDHRYLNKDGSLSDKITENSLYGLELRGGANPGFTFKDNEGKYLTLIGSTGTVKSKNKVVSKDEIFTLEISYPQVGLRAHNGKFASIKQGVDLYANQADAEEKEIFQLEYQNSSKKWKIRTCDGKYWTVTSVNSGIKATSGDNNESSLFDIIHLTSGKVLIKASNNMYVSSKKLGLMSATGENAEDVESLFQAILLNRPMIIFKSDFGLVGIRNNRVECNMSTYEAFQLETANDGNYMLKVCGNKDAYWRTGDDNGIKIDGSAPPQQFILQFDSGTHCAILASNGKYIRGEQNGLMKADSDEINKASLWEF
Sbjct:    1 MSSNGVNGSSESFNPILTWEMGIVNEAGKYLTAETFGFKINVSATSLKKRQLWTMIPDKTAEYFFIKSHLNRYLSSDKDGKVSCEVEENGVEEQFFIEYCPKGTGKWAFKSVAYGYYLTGNEDRISCFSKSPSWWSARLAIHPQVHMQNMKRQRYVRLQGDELHGDQVIPWGFDSLITLEHSTCGKVAVCSRDHRYLNKDGSLSDKITENSLYGLELRGGANPGFTFKDNEGKYLTLIGSTGTVKSKNKVVSKDEIFTLEISYPQVGLRAHNGKFASIKQGVDLYANQADAEEKEIFQLEYQNSSKKWKIRTCDGKYWTVTSVNSGIKATSGDNNESSLFDIIHLTSGKVLIKASNNMYVSSKKLGLMSATGENAEDVESLFQAILLNRPMIIFKSDFGLVGIRNNRVECNMSTYEAFQLETANDGNYMLKVCGNKDAYWRTGDDNGIKIDGSAPPQQFILQFDSGTHCAILASNGKYIRGEQNGLMKADSDEINKASLWEF 502
The following BLAST results are available for this feature:
BLAST of Fascin vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
FSCN12.467e-11240.28fascin actin-bundling protein 1 [Source:HGNC Symbo... [more]
FSCN23.804e-10036.13fascin actin-bundling protein 2, retinal [Source:H... [more]
FSCN26.725e-9735.14fascin actin-bundling protein 2, retinal [Source:H... [more]
FSCN31.279e-2822.65fascin actin-bundling protein 3 [Source:HGNC Symbo... [more]
FSCN12.290e-2440.00fascin actin-bundling protein 1 [Source:HGNC Symbo... [more]
back to top
BLAST of Fascin vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0
Match NameE-valueIdentityDescription
back to top
BLAST of Fascin vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 4
Match NameE-valueIdentityDescription
sn1.739e-11138.51gene:FBgn0003447 transcript:FBtr0301679[more]
sn1.739e-11138.51gene:FBgn0003447 transcript:FBtr0301677[more]
sn1.739e-11138.51gene:FBgn0003447 transcript:FBtr0071101[more]
sn1.739e-11138.51gene:FBgn0003447 transcript:FBtr0071102[more]
back to top
BLAST of Fascin vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
fscn1a2.924e-11439.92fascin actin-bundling protein 1a [Source:ZFIN;Acc:... [more]
fscn2b1.559e-10739.39fascin actin-bundling protein 2b, retinal [Source:... [more]
fscn1b2.738e-10538.39fascin actin-bundling protein 1b [Source:ZFIN;Acc:... [more]
fscn1b2.738e-10538.39fascin actin-bundling protein 1b [Source:ZFIN;Acc:... [more]
fscn2a2.240e-10138.90fascin actin-bundling protein 2a, retinal [Source:... [more]
back to top
BLAST of Fascin vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 3
Match NameE-valueIdentityDescription
fscn13.256e-11242.02fascin actin-bundling protein 1 [Source:NCBI gene;... [more]
tldc21.207e-9938.21TBC/LysM-associated domain containing 2 [Source:Xe... [more]
tldc28.354e-8738.91TBC/LysM-associated domain containing 2 [Source:Xe... [more]
back to top
BLAST of Fascin vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Fscn13.753e-10639.49fascin actin-bundling protein 1 [Source:MGI Symbol... [more]
Fscn24.542e-10537.30fascin actin-bundling protein 2 [Source:MGI Symbol... [more]
Fscn11.898e-4738.71fascin actin-bundling protein 1 [Source:MGI Symbol... [more]
Fscn13.375e-4138.43fascin actin-bundling protein 1 [Source:MGI Symbol... [more]
Fscn35.483e-3324.05fascin actin-bundling protein 3 [Source:MGI Symbol... [more]
back to top
BLAST of Fascin vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q16658|FSCN1_HUMAN1.185e-11140.28Fascin OS=Homo sapiens OX=9606 GN=FSCN1 PE=1 SV=3[more]
sp|Q24524|SING_DROME1.744e-11038.51Protein singed OS=Drosophila melanogaster OX=7227 ... [more]
sp|Q61553|FSCN1_MOUSE2.626e-10539.49Fascin OS=Mus musculus OX=10090 GN=Fscn1 PE=1 SV=4[more]
sp|P85845|FSCN1_RAT2.255e-10439.29Fascin OS=Rattus norvegicus OX=10116 GN=Fscn1 PE=1... [more]
sp|Q32M02|FSCN2_MOUSE3.177e-10437.30Fascin-2 OS=Mus musculus OX=10090 GN=Fscn2 PE=2 SV... [more]
back to top
BLAST of Fascin vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
T1E1F20.000e+072.31Fascin OS=Dendrocoelum lacteum OX=27895 PE=2 SV=1[more]
A0A267H3R03.626e-16949.38Fascin OS=Macrostomum lignano OX=282301 GN=BOX15_M... [more]
A0A1I8I4V47.648e-16848.69Fascin OS=Macrostomum lignano OX=282301 PE=3 SV=1[more]
A0A1I8I1J33.763e-16748.49Fascin OS=Macrostomum lignano OX=282301 PE=3 SV=1[more]
A0A1I8GT815.578e-16747.86Uncharacterized protein OS=Macrostomum lignano OX=... [more]
back to top
BLAST of Fascin vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 4
Match NameE-valueIdentityDescription
fscn1a2.757e-11039.92fascin [Source:NCBI gene;Acc:103025781][more]
fscn2b1.978e-10638.76fascin-2 [Source:NCBI gene;Acc:103025956][more]
fscn2a1.128e-10438.93fascin-2-like [Source:NCBI gene;Acc:103030006][more]
fscn1b8.813e-10237.45fascin actin-bundling protein 1b [Source:ZFIN;Acc:... [more]
back to top
BLAST of Fascin vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
back to top
BLAST of Fascin vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
back to top
BLAST of Fascin vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1
Match NameE-valueIdentityDescription
EDO448343.715e-9235.94Fascin [Source:UniProtKB/TrEMBL;Acc:A7RUD3][more]
back to top
BLAST of Fascin vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSORLT00000012063.24.849e-11340.94fascin [Source:NCBI gene;Acc:101170402][more]
fscn1a9.006e-10939.03fascin actin-bundling protein 1 [Source:NCBI gene;... [more]
fscn2a5.339e-10638.75fascin-2-like [Source:NCBI gene;Acc:101170272][more]
fscn2b8.766e-9936.75fascin actin-bundling protein 2, retinal [Source:N... [more]
fscn2b8.766e-9936.75fascin actin-bundling protein 2, retinal [Source:N... [more]
back to top
BLAST of Fascin vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 1
Match NameE-valueIdentityDescription
SMESG000037971.10.000e+0100.00SMESG000037971.1[more]
back to top
Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30008911 ID=SMED30008911|Name=Fascin|organism=Schmidtea mediterranea sexual|type=transcript|length=2164bp
TTATTATAAGGCAACCAAATCTTAAATAGGCGAATGTTTAGTTGGTTAAT
CATTTTGAGAAATGAATAAATCAAATGAGACAACATCGATTACAAAACCC
AGACACACACACGTTCAGACAAATGTAATGCCAATGAATAAGGAAGTCTG
ACTAATTGTGAATTATTACGTATGCGATTCGTTAAAGAAATTTACTTACA
CACCAAATGTAGGACAGGATTATGAAAGATTGCGATTAGTCATTTCAAAC
TGATTGGTTATTTGCTTGTAACGTGTTTGTACATATAATCGATTATTTAC
GATAAGTTAATCTTCATTTTTGCGAATTTTCTCAGTTGATTTTAAAATAT
CGTTTCCAAAAAGTATGAGTTCAAACGGTGTGAATGGATCTTCAGAATCG
TTTAATCCCATATTAACATGGGAAATGGGTATTGTGAATGAGGCAGGAAA
ATATTTAACAGCAGAAACGTTTGGATTTAAAATAAATGTTTCTGCTACAT
CTTTGAAAAAACGACAACTTTGGACAATGATTCCCGATAAGACGGCAGAA
TATTTTTTTATAAAATCACACCTTAACCGATATTTGAGTTCAGACAAAGA
TGGTAAAGTTTCATGTGAAGTTGAAGAAAATGGTGTTGAAGAACAGTTTT
TCATCGAATATTGTCCTAAAGGAACTGGAAAATGGGCTTTTAAGTCTGTT
GCCTATGGGTATTATTTGACGGGAAATGAAGACAGAATATCATGCTTTTC
TAAATCGCCATCATGGTGGAGTGCAAGATTAGCAATTCATCCACAGGTCC
ATATGCAAAATATGAAAAGACAACGATATGTTAGATTGCAGGGTGACGAG
TTACATGGCGATCAAGTTATTCCGTGGGGATTTGATTCTCTAATCACTTT
AGAGCATAGTACATGTGGAAAAGTTGCTGTATGTTCAAGAGATCACAGAT
ATTTAAATAAAGATGGAAGCTTGTCCGATAAAATTACGGAAAATAGTTTA
TATGGTCTTGAACTGCGTGGTGGTGCAAATCCCGGTTTCACTTTCAAAGA
CAATGAAGGAAAATACTTAACACTCATTGGTTCAACCGGAACTGTGAAAT
CCAAAAACAAAGTTGTTAGCAAAGATGAAATATTTACTTTAGAAATCAGT
TATCCTCAAGTTGGATTACGAGCACACAATGGAAAATTTGCTTCAATCAA
ACAAGGAGTTGATTTGTATGCAAACCAGGCAGATGCTGAAGAAAAGGAAA
TATTTCAATTAGAATATCAAAATTCTTCTAAAAAGTGGAAAATCAGAACT
TGTGATGGCAAATATTGGACCGTTACTTCAGTCAATAGTGGTATTAAAGC
AACAAGCGGAGATAATAACGAGTCGTCTTTATTCGATATAATTCACCTAA
CGAGTGGTAAAGTGTTGATAAAAGCAAGCAACAATATGTATGTATCGTCT
AAAAAATTGGGATTAATGTCTGCAACTGGTGAAAATGCTGAAGATGTGGA
AAGTCTTTTCCAAGCTATTTTGTTGAACCGTCCTATGATAATTTTCAAAT
CTGATTTTGGTCTGGTTGGAATTCGAAATAATAGAGTCGAATGCAATATG
TCGACTTATGAAGCTTTTCAATTGGAAACTGCTAATGATGGAAACTATAT
GCTTAAAGTATGTGGAAATAAAGATGCATATTGGAGAACTGGTGACGATA
ACGGTATCAAAATTGACGGGTCTGCTCCACCACAGCAATTTATTCTCCAG
TTTGACAGTGGAACTCATTGCGCAATTTTGGCTTCAAATGGTAAATATAT
CCGCGGTGAACAAAACGGATTGATGAAGGCCGATTCGGATGAAATCAACA
AAGCCTCACTGTGGGAATTTTAGATTTTGTAAATAAGAATTCATTCGACC
TTTTTGTTTTTCACTTTGATACATCAATCTGTTTAATTTCTGTTGATAAA
ATGTAAAATTTAGTTGTGGAATGATTCTGTAAATGTATTACATAAATTTA
TGTTGGAATAATTGATACATTTCCCGGGTAGACGTTGCAAGCTTCGTTTG
ATGTATTTTTTTATTTTGCAATAATTAATTGATTTGCATTATCAATGTAT
TGTTTTGATAAACAAATAGAATTGTTAATATGTGAACTTTTAAATAGTCA
TTATTTTGTTTACG
back to top

protein sequence of SMED30008911-orf-1

>SMED30008911-orf-1 ID=SMED30008911-orf-1|Name=SMED30008911-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=503bp
MSSNGVNGSSESFNPILTWEMGIVNEAGKYLTAETFGFKINVSATSLKKR
QLWTMIPDKTAEYFFIKSHLNRYLSSDKDGKVSCEVEENGVEEQFFIEYC
PKGTGKWAFKSVAYGYYLTGNEDRISCFSKSPSWWSARLAIHPQVHMQNM
KRQRYVRLQGDELHGDQVIPWGFDSLITLEHSTCGKVAVCSRDHRYLNKD
GSLSDKITENSLYGLELRGGANPGFTFKDNEGKYLTLIGSTGTVKSKNKV
VSKDEIFTLEISYPQVGLRAHNGKFASIKQGVDLYANQADAEEKEIFQLE
YQNSSKKWKIRTCDGKYWTVTSVNSGIKATSGDNNESSLFDIIHLTSGKV
LIKASNNMYVSSKKLGLMSATGENAEDVESLFQAILLNRPMIIFKSDFGL
VGIRNNRVECNMSTYEAFQLETANDGNYMLKVCGNKDAYWRTGDDNGIKI
DGSAPPQQFILQFDSGTHCAILASNGKYIRGEQNGLMKADSDEINKASLW
EF*
back to top
Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000020protonephridia
PLANA:0000099neuron
PLANA:0000101muscle cell
PLANA:0000120progenitor cell
PLANA:0000136whole organism
PLANA:0003116parenchymal cell
PLANA:0003117parapharyngeal cell
Vocabulary: INTERPRO
TermDefinition
IPR010431Fascin
IPR030146FSCN1
IPR022768Fascin-domain
IPR024703Fascin_metazoans
IPR008999Actin-crosslinking
Vocabulary: molecular function
TermDefinition
GO:0051015actin filament binding
GO:0030674protein binding, bridging
GO:0003779actin binding
Vocabulary: cellular component
TermDefinition
GO:0005737cytoplasm
GO:0005856cytoskeleton
Vocabulary: biological process
TermDefinition
GO:0007015actin filament organization
GO:0016477cell migration
GO:0030036actin cytoskeleton organization
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR024703Fascin, metazoansPIRSFPIRSF005682Fascincoord: 1..502
e-value: 1.5E-138
score: 460.1
NoneNo IPR availableGENE3DG3DSA:2.80.10.50coord: 142..263
e-value: 6.7E-29
score: 102.6
NoneNo IPR availableGENE3DG3DSA:2.80.10.50coord: 265..392
e-value: 7.0E-29
score: 102.5
NoneNo IPR availableGENE3DG3DSA:2.80.10.50coord: 7..141
e-value: 1.8E-39
score: 136.9
NoneNo IPR availableGENE3DG3DSA:2.80.10.50coord: 393..502
e-value: 1.2E-26
score: 95.2
IPR022768Fascin domainPFAMPF06268Fascincoord: 272..375
e-value: 5.1E-15
score: 55.7
coord: 28..133
e-value: 5.5E-21
score: 74.9
coord: 146..259
e-value: 6.0E-9
score: 36.1
coord: 407..501
e-value: 3.4E-9
score: 36.9
IPR022768Fascin domainCDDcd00257Fascincoord: 22..133
e-value: 1.97615E-24
score: 95.8048
IPR022768Fascin domainCDDcd00257Fascincoord: 264..373
e-value: 8.00983E-23
score: 91.5676
IPR010431FascinPANTHERPTHR10551FASCINcoord: 14..502
IPR030146Fascin-1PANTHERPTHR10551:SF23FASCINcoord: 14..502
IPR008999Actin-crosslinkingSUPERFAMILYSSF50405Actin-crosslinking proteinscoord: 142..258
IPR008999Actin-crosslinkingSUPERFAMILYSSF50405Actin-crosslinking proteinscoord: 225..322
IPR008999Actin-crosslinkingSUPERFAMILYSSF50405Actin-crosslinking proteinscoord: 20..136
IPR008999Actin-crosslinkingSUPERFAMILYSSF50405Actin-crosslinking proteinscoord: 385..502