Profilin

Overview
NameProfilin
Smed IDSMED30008903
Length (bp)2067
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Profilin (SMED30008903) t-SNE clustered cells

Violin plots show distribution of expression levels for Profilin (SMED30008903) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Profilin (SMED30008903) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Profilin (SMED30008903) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30008903

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 18

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
head regionSMED30008903h1SMcG0017955 SmedASXL_015569SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016		whole organism asexual adult RNA-sequencing evidence
Smed sexual biotypeSMED30008903h1SMcG0014372 Contig4969uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30008903h1SMcG0014372 Contig4969newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30008903h1SMcG0014371 Contig4969uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30008903h1SMcG0014371 Contig4969newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30008903h1SMcG0017955 Contig4969uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30008903h1SMcG0017955 Contig4969newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30008903h1SMcG0017955 Contig29023newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30008903h1SMcG0017955 Contig29023uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30008903h1SMcG0017955 Contig50022newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30008903h1SMcG0017955 Contig50022uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
neoblastSMED30008903h1SMcG0017955 dd_Smed_v4_11814_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymaSMED30008903h1SMcG0017955 dd_Smed_v4_11814_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
nervous systemSMED30008903h1SMcG0017955 dd_Smed_v4_11814_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30008903h1SMcG0017955 dd_Smed_v4_11814_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neuronSMED30008903h1SMcG0017955 dd_Smed_v4_11814_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		whole organism asexual adult colorimetric in situ hybridization evidence
non-ciliated neuronSMED30008903h1SMcG0017955 dd_Smed_v4_11814_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
head regionSMED30008903h1SMcG0017955 dd_Smed_v6_11814_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017		whole organism asexual adult RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Profilin vs. Ensembl Human
Match: PFN4 (profilin family member 4 [Source:HGNC Symbol;Acc:HGNC:31103])

HSP 1 Score: 78.9518 bits (193), Expect = 6.793e-17
Identity = 41/115 (35.65%), Postives = 70/115 (60.87%), Query Frame = 1 
Query: 1063 TGHVSNACLIDKNLDGKLLASTNGFTLSQDQV-VXXXXXXXXXXXXRENDFYFGGRKFECIRADKESIYAKNGNSGVILMQTNQLIVLATYNDHMFPAVAVESVEKLCQYFKEKG 1404
            T HV +A LI K  +  L  ++ GF ++   V   +     +P   R    YF G+ + C+RAD+ S+YAKN N+GV++++T+  +++ATY + M+P++ VE+ E L  Y ++KG
Sbjct:   15 TKHVDSAALI-KIQERSLCVASPGFNVTPSDVRTLVNGFAKNPLQARREGLYFKGKDYRCVRADEYSLYAKNENTGVVVVKTHLYLLVATYTEGMYPSICVEATESLGDYLRKKG 128
[Close]
BLAST of Profilin vs. Ensembl Fly
Match: chic (gene:FBgn0000308 transcript:FBtr0079236)

HSP 1 Score: 51.9878 bits (123), Expect = 8.336e-8
Identity = 33/120 (27.50%), Postives = 62/120 (51.67%), Query Frame = 1 
Query: 1033 QNLITDALLRTGHVSNACLIDKNLDGKLLASTNGFTLSQDQVVXXXXXXXXXXXXRENDFYFGGRKFECIRADKESIYAKNGNSGVILMQTNQLIVLATYNDHMFPAVAVESVEKLCQYF 1392
            Q+ + + LL +  V+ AC+     DG + A ++GF ++++++  +I+ F     +  N     G+++  +      + AK G SGV  M+T Q ++++ Y D + P  A   VEKL  Y 
Sbjct:    4 QDYVDNQLLASQCVTKACIAGH--DGNIWAQSSGFEVTKEELSKLISGFDQQDGLTSNGVTLAGQRYIYLSGTDRVVRAKLGRSGVHCMKTTQAVIVSIYEDPVQPQQAASVVEKLGDYL 121
[Close]
BLAST of Profilin vs. Ensembl Fly
Match: chic (gene:FBgn0000308 transcript:FBtr0309213)

HSP 1 Score: 51.9878 bits (123), Expect = 8.336e-8
Identity = 33/120 (27.50%), Postives = 62/120 (51.67%), Query Frame = 1 
Query: 1033 QNLITDALLRTGHVSNACLIDKNLDGKLLASTNGFTLSQDQVVXXXXXXXXXXXXRENDFYFGGRKFECIRADKESIYAKNGNSGVILMQTNQLIVLATYNDHMFPAVAVESVEKLCQYF 1392
            Q+ + + LL +  V+ AC+     DG + A ++GF ++++++  +I+ F     +  N     G+++  +      + AK G SGV  M+T Q ++++ Y D + P  A   VEKL  Y 
Sbjct:    4 QDYVDNQLLASQCVTKACIAGH--DGNIWAQSSGFEVTKEELSKLISGFDQQDGLTSNGVTLAGQRYIYLSGTDRVVRAKLGRSGVHCMKTTQAVIVSIYEDPVQPQQAASVVEKLGDYL 121
[Close]
BLAST of Profilin vs. Ensembl Fly
Match: chic (gene:FBgn0000308 transcript:FBtr0079235)

HSP 1 Score: 51.9878 bits (123), Expect = 8.336e-8
Identity = 33/120 (27.50%), Postives = 62/120 (51.67%), Query Frame = 1 
Query: 1033 QNLITDALLRTGHVSNACLIDKNLDGKLLASTNGFTLSQDQVVXXXXXXXXXXXXRENDFYFGGRKFECIRADKESIYAKNGNSGVILMQTNQLIVLATYNDHMFPAVAVESVEKLCQYF 1392
            Q+ + + LL +  V+ AC+     DG + A ++GF ++++++  +I+ F     +  N     G+++  +      + AK G SGV  M+T Q ++++ Y D + P  A   VEKL  Y 
Sbjct:    4 QDYVDNQLLASQCVTKACIAGH--DGNIWAQSSGFEVTKEELSKLISGFDQQDGLTSNGVTLAGQRYIYLSGTDRVVRAKLGRSGVHCMKTTQAVIVSIYEDPVQPQQAASVVEKLGDYL 121
[Close]
BLAST of Profilin vs. Ensembl Fly
Match: chic (gene:FBgn0000308 transcript:FBtr0309212)

HSP 1 Score: 51.9878 bits (123), Expect = 8.336e-8
Identity = 33/120 (27.50%), Postives = 62/120 (51.67%), Query Frame = 1 
Query: 1033 QNLITDALLRTGHVSNACLIDKNLDGKLLASTNGFTLSQDQVVXXXXXXXXXXXXRENDFYFGGRKFECIRADKESIYAKNGNSGVILMQTNQLIVLATYNDHMFPAVAVESVEKLCQYF 1392
            Q+ + + LL +  V+ AC+     DG + A ++GF ++++++  +I+ F     +  N     G+++  +      + AK G SGV  M+T Q ++++ Y D + P  A   VEKL  Y 
Sbjct:    4 QDYVDNQLLASQCVTKACIAGH--DGNIWAQSSGFEVTKEELSKLISGFDQQDGLTSNGVTLAGQRYIYLSGTDRVVRAKLGRSGVHCMKTTQAVIVSIYEDPVQPQQAASVVEKLGDYL 121
[Close]
BLAST of Profilin vs. Ensembl Fly
Match: chic (gene:FBgn0000308 transcript:FBtr0079234)

HSP 1 Score: 51.9878 bits (123), Expect = 8.336e-8
Identity = 33/120 (27.50%), Postives = 62/120 (51.67%), Query Frame = 1 
Query: 1033 QNLITDALLRTGHVSNACLIDKNLDGKLLASTNGFTLSQDQVVXXXXXXXXXXXXRENDFYFGGRKFECIRADKESIYAKNGNSGVILMQTNQLIVLATYNDHMFPAVAVESVEKLCQYF 1392
            Q+ + + LL +  V+ AC+     DG + A ++GF ++++++  +I+ F     +  N     G+++  +      + AK G SGV  M+T Q ++++ Y D + P  A   VEKL  Y 
Sbjct:    4 QDYVDNQLLASQCVTKACIAGH--DGNIWAQSSGFEVTKEELSKLISGFDQQDGLTSNGVTLAGQRYIYLSGTDRVVRAKLGRSGVHCMKTTQAVIVSIYEDPVQPQQAASVVEKLGDYL 121
[Close]
BLAST of Profilin vs. Ensembl Zebrafish
Match: si:ch211-175f11.5 (si:ch211-175f11.5 [Source:ZFIN;Acc:ZDB-GENE-131121-583])

HSP 1 Score: 90.5077 bits (223), Expect = 3.495e-21
Identity = 48/130 (36.92%), Postives = 77/130 (59.23%), Query Frame = 1 
Query: 1021 MNPLQNLITDALLRTGHVSNACL-IDKNLDGKLLASTNGFTLSQDQVVXXXXXXXXXXXXRENDFYFGGRKFECIRADKESIYAKNGNSGVILMQTNQLIVLATYNDHMFPAVAVESVEKLCQYFKEKGK 1407
            MNPL  L+ D L+ T HV  A + + K  D   + + + FT+  +++   + +F   +   +    F  + + C+RADK SIYAKN   G+IL++T   +++ATY+  M P++ VE+VEKL  Y +EKGK
Sbjct:    1 MNPLPKLLEDCLISTKHVERAAVFVAKTCD---ITAASNFTVCLEEIQIFLDAFKHLNETMKKGLIFRDKPYTCVRADKHSIYAKNEGRGLILVRTALYVIVATYSQTMHPSICVEAVEKLGDYLREKGK 127
[Close]
BLAST of Profilin vs. Ensembl Xenopus
Match: PFN4 (profilin family member 4 [Source:NCBI gene;Acc:100495970])

HSP 1 Score: 90.1225 bits (222), Expect = 8.647e-21
Identity = 51/127 (40.16%), Postives = 81/127 (63.78%), Query Frame = 1 
Query: 1021 MNPLQNLITDALLRTGHVSNACLIDKNLDGKLLASTNGFTLSQDQVVXXXXXXXXXXXXRENDFYFGGRKFECIRADKESIYAKNGNSGVILMQTNQLIVLATYNDHMFPAVAVESVEKLCQYFKEK 1401
            MN +QNL+ D+L++T HV  A LI +  +G +  S   F +    + +I+ +F +PS++R+       + + C+RADK SIYAK  + G++L++T   I+LATY D M+P+V VE+ E L  YF+EK
Sbjct:    1 MNQIQNLLYDSLIKTQHVEAAALI-RIKEGAVFPSPPRFQVQPQIMKTIVDAFKNPSALRKEGLQLWDKSYHCVRADKNSIYAKCDDGGLVLVKTKSNILLATYRDGMYPSVCVEAAETLGSYFREK 126
[Close]
BLAST of Profilin vs. Ensembl Mouse
Match: Pfn4 (profilin family, member 4 [Source:MGI Symbol;Acc:MGI:1920121])

HSP 1 Score: 81.6481 bits (200), Expect = 5.914e-18
Identity = 44/115 (38.26%), Postives = 70/115 (60.87%), Query Frame = 1 
Query: 1063 TGHVSNACLIDKNLDGKLLASTNGFT-LSQDQVVXXXXXXXXXXXXRENDFYFGGRKFECIRADKESIYAKNGNSGVILMQTNQLIVLATYNDHMFPAVAVESVEKLCQYFKEKG 1404
            T HV +A LI K  +  L  ++ GF+ +  D    +     +P   R    YF  + ++C+RAD  S+YAKN N+GV++++TN  +V+ATY   M+P+V VE+ EKL +Y ++KG
Sbjct:   15 TKHVDSAALI-KLQEKTLCVTSPGFSVMPSDVRTLLNGFAKNPLLTRREGLYFKEKDYKCVRADDYSLYAKNENTGVVVVKTNMYLVVATYTAGMYPSVCVEATEKLGEYLRKKG 128
[Close]
BLAST of Profilin vs. Ensembl Mouse
Match: Pfn4 (profilin family, member 4 [Source:MGI Symbol;Acc:MGI:1920121])

HSP 1 Score: 81.6481 bits (200), Expect = 5.914e-18
Identity = 44/115 (38.26%), Postives = 70/115 (60.87%), Query Frame = 1 
Query: 1063 TGHVSNACLIDKNLDGKLLASTNGFT-LSQDQVVXXXXXXXXXXXXRENDFYFGGRKFECIRADKESIYAKNGNSGVILMQTNQLIVLATYNDHMFPAVAVESVEKLCQYFKEKG 1404
            T HV +A LI K  +  L  ++ GF+ +  D    +     +P   R    YF  + ++C+RAD  S+YAKN N+GV++++TN  +V+ATY   M+P+V VE+ EKL +Y ++KG
Sbjct:   15 TKHVDSAALI-KLQEKTLCVTSPGFSVMPSDVRTLLNGFAKNPLLTRREGLYFKEKDYKCVRADDYSLYAKNENTGVVVVKTNMYLVVATYTAGMYPSVCVEATEKLGEYLRKKG 128
[Close]
BLAST of Profilin vs. Ensembl Mouse
Match: Pfn4 (profilin family, member 4 [Source:MGI Symbol;Acc:MGI:1920121])

HSP 1 Score: 73.559 bits (179), Expect = 3.987e-15
Identity = 41/110 (37.27%), Postives = 66/110 (60.00%), Query Frame = 1 
Query: 1063 TGHVSNACLIDKNLDGKLLASTNGFT-LSQDQVVXXXXXXXXXXXXRENDFYFGGRKFECIRADKESIYAKNGNSGVILMQTNQLIVLATYNDHMFPAVAVESVEKLCQY 1389
            T HV +A LI K  +  L  ++ GF+ +  D    +     +P   R    YF  + ++C+RAD  S+YAKN N+GV++++TN  +V+ATY   M+P+V VE+ EKL ++
Sbjct:   15 TKHVDSAALI-KLQEKTLCVTSPGFSVMPSDVRTLLNGFAKNPLLTRREGLYFKEKDYKCVRADDYSLYAKNENTGVVVVKTNMYLVVATYTAGMYPSVCVEATEKLGKF 123
[Close]
BLAST of Profilin vs. UniProt/SwissProt
Match: sp|Q9D6I3|PROF4_MOUSE (Profilin-4 OS=Mus musculus OX=10090 GN=Pfn4 PE=1 SV=1)

HSP 1 Score: 81.6481 bits (200), Expect = 4.137e-17
Identity = 44/115 (38.26%), Postives = 70/115 (60.87%), Query Frame = 1 
Query: 1063 TGHVSNACLIDKNLDGKLLASTNGFT-LSQDQVVXXXXXXXXXXXXRENDFYFGGRKFECIRADKESIYAKNGNSGVILMQTNQLIVLATYNDHMFPAVAVESVEKLCQYFKEKG 1404
            T HV +A LI K  +  L  ++ GF+ +  D    +     +P   R    YF  + ++C+RAD  S+YAKN N+GV++++TN  +V+ATY   M+P+V VE+ EKL +Y ++KG
Sbjct:   15 TKHVDSAALI-KLQEKTLCVTSPGFSVMPSDVRTLLNGFAKNPLLTRREGLYFKEKDYKCVRADDYSLYAKNENTGVVVVKTNMYLVVATYTAGMYPSVCVEATEKLGEYLRKKG 128
[Close]
BLAST of Profilin vs. UniProt/SwissProt
Match: sp|Q8NHR9|PROF4_HUMAN (Profilin-4 OS=Homo sapiens OX=9606 GN=PFN4 PE=1 SV=1)

HSP 1 Score: 78.9518 bits (193), Expect = 3.262e-16
Identity = 41/115 (35.65%), Postives = 70/115 (60.87%), Query Frame = 1 
Query: 1063 TGHVSNACLIDKNLDGKLLASTNGFTLSQDQV-VXXXXXXXXXXXXRENDFYFGGRKFECIRADKESIYAKNGNSGVILMQTNQLIVLATYNDHMFPAVAVESVEKLCQYFKEKG 1404
            T HV +A LI K  +  L  ++ GF ++   V   +     +P   R    YF G+ + C+RAD+ S+YAKN N+GV++++T+  +++ATY + M+P++ VE+ E L  Y ++KG
Sbjct:   15 TKHVDSAALI-KIQERSLCVASPGFNVTPSDVRTLVNGFAKNPLQARREGLYFKGKDYRCVRADEYSLYAKNENTGVVVVKTHLYLLVATYTEGMYPSICVEATESLGDYLRKKG 128
[Close]
BLAST of Profilin vs. UniProt/SwissProt
Match: sp|Q2NKT1|PROF4_BOVIN (Profilin-4 OS=Bos taurus OX=9913 GN=PFN4 PE=2 SV=1)

HSP 1 Score: 77.7962 bits (190), Expect = 9.385e-16
Identity = 43/115 (37.39%), Postives = 70/115 (60.87%), Query Frame = 1 
Query: 1063 TGHVSNACLIDKNLDGKLLASTNGFT-LSQDQVVXXXXXXXXXXXXRENDFYFGGRKFECIRADKESIYAKNGNSGVILMQTNQLIVLATYNDHMFPAVAVESVEKLCQYFKEKG 1404
            T HV +A LI K  +  L  ++ GF+ +  D    +     +P   R    YF  + ++C+RAD  S+YAKN N+GVI+++T+  +++ATY++ M+P+V VE+ EKL  Y + KG
Sbjct:   15 TKHVDSAALI-KLQERSLCVASPGFSVMPSDVRTLVNGFAKNPLKTRREGLYFKEKDYKCVRADDYSLYAKNENTGVIVVKTHLYLLVATYSEGMYPSVCVEATEKLGDYLRRKG 128
[Close]
BLAST of Profilin vs. UniProt/SwissProt
Match: sp|Q5IRJ7|PROF4_RAT (Profilin-4 OS=Rattus norvegicus OX=10116 GN=Pfn4 PE=1 SV=1)

HSP 1 Score: 72.7886 bits (177), Expect = 4.945e-14
Identity = 41/115 (35.65%), Postives = 68/115 (59.13%), Query Frame = 1 
Query: 1063 TGHVSNACLIDKNLDGKLLASTNGFT-LSQDQVVXXXXXXXXXXXXRENDFYFGGRKFECIRADKESIYAKNGNSGVILMQTNQLIVLATYNDHMFPAVAVESVEKLCQYFKEKG 1404
            T HV  A LI K  +  L  ++ GF+ +  D    +     +P   R    YF  + ++C+RAD  S+YAK  N+GV++++T+  +++ATY   M+P+V VE+ EKL +Y ++KG
Sbjct:   15 TKHVDGAALI-KLQEKTLCVTSPGFSVMPCDVRTLLNGFAKNPLLTRREGLYFREKDYKCVRADDCSLYAKKENTGVVVVKTHMYLLVATYTAGMYPSVCVEATEKLGEYLRKKG 128
[Close]
BLAST of Profilin vs. UniProt/SwissProt
Match: sp|P19984|PROF2_ACACA (Profilin-2 OS=Acanthamoeba castellanii OX=5755 PE=1 SV=3)

HSP 1 Score: 72.0182 bits (175), Expect = 9.743e-14
Identity = 42/124 (33.87%), Postives = 68/124 (54.84%), Query Frame = 1 
Query: 1033 QNLITDALLRTGHVSNACLIDKNLDGKLLASTNGFTLSQDQVVXXXXXXXXXXXXRENDFYFGGRKFECIRADKESIYAKNGNSGVILMQTNQLIVLATYNDHMFPAVAVESVEKLCQYFKEKG 1404
            Q  +   L+ TG V+ A +I    DG   A++ GF +S     ++  +F   ++IR N F   G ++  IRAD  S+Y K G++GVI ++T++ I++  YN+ + P  A   VEKL  Y   +G
Sbjct:    4 QTYVDTNLVGTGAVTQAAIIGH--DGNTWATSAGFAVSPANGAALANAFKDATAIRSNGFELAGTRYVTIRADDRSVYGKKGSAGVITVKTSKAILIGVYNEKIQPGTAANVVEKLADYLIGQG 125
[Close]
BLAST of Profilin vs. TrEMBL
Match: A0A2C9KMD0 (Profilin OS=Biomphalaria glabrata OX=6526 GN=106060976 PE=3 SV=1)

HSP 1 Score: 120.553 bits (301), Expect = 2.572e-28
Identity = 62/128 (48.44%), Postives = 89/128 (69.53%), Query Frame = 1 
Query: 1021 MNPLQNLITDALLRTGHVSNACLIDKNLDGKLLASTNGFTLSQDQVVXXXXXXXXXXXXRENDFYFGGRKFECIRADKESIYAKNGNSGVILMQTNQLIVLATYNDHMFPAVAVESVEKLCQYFKEKG 1404
            MN L NL+ DAL+ TGHV    +I +N D  + AS+ GF L  DQV  ++ +F +P   R++  YF   +++C+RADK SIYAK    G++L++T  L+++ATYN++MFP+V VE+VEKL  YFKEKG
Sbjct:    1 MNQLSNLLQDALISTGHVHQCAIIRRN-DANVRASSLGFNLYPDQVSLLLDAFKNPPQTRQDGIYFDEAQYKCVRADKNSIYAKCAKKGLVLVKTVTLMIIATYNENMFPSVCVEAVEKLADYFKEKG 127
[Close]
BLAST of Profilin vs. TrEMBL
Match: A0A2C9KM56 (Profilin OS=Biomphalaria glabrata OX=6526 GN=106060976 PE=3 SV=1)

HSP 1 Score: 120.939 bits (302), Expect = 2.605e-28
Identity = 62/128 (48.44%), Postives = 89/128 (69.53%), Query Frame = 1 
Query: 1021 MNPLQNLITDALLRTGHVSNACLIDKNLDGKLLASTNGFTLSQDQVVXXXXXXXXXXXXRENDFYFGGRKFECIRADKESIYAKNGNSGVILMQTNQLIVLATYNDHMFPAVAVESVEKLCQYFKEKG 1404
            MN L NL+ DAL+ TGHV    +I +N D  + AS+ GF L  DQV  ++ +F +P   R++  YF   +++C+RADK SIYAK    G++L++T  L+++ATYN++MFP+V VE+VEKL  YFKEKG
Sbjct:    8 MNQLSNLLQDALISTGHVHQCAIIRRN-DANVRASSLGFNLYPDQVSLLLDAFKNPPQTRQDGIYFDEAQYKCVRADKNSIYAKCAKKGLVLVKTVTLMIIATYNENMFPSVCVEAVEKLADYFKEKG 134
[Close]
BLAST of Profilin vs. TrEMBL
Match: A0A2C9KM57 (Profilin OS=Biomphalaria glabrata OX=6526 GN=106060976 PE=3 SV=1)

HSP 1 Score: 120.939 bits (302), Expect = 3.469e-28
Identity = 62/128 (48.44%), Postives = 89/128 (69.53%), Query Frame = 1 
Query: 1021 MNPLQNLITDALLRTGHVSNACLIDKNLDGKLLASTNGFTLSQDQVVXXXXXXXXXXXXRENDFYFGGRKFECIRADKESIYAKNGNSGVILMQTNQLIVLATYNDHMFPAVAVESVEKLCQYFKEKG 1404
            MN L NL+ DAL+ TGHV    +I +N D  + AS+ GF L  DQV  ++ +F +P   R++  YF   +++C+RADK SIYAK    G++L++T  L+++ATYN++MFP+V VE+VEKL  YFKEKG
Sbjct:   23 MNQLSNLLQDALISTGHVHQCAIIRRN-DANVRASSLGFNLYPDQVSLLLDAFKNPPQTRQDGIYFDEAQYKCVRADKNSIYAKCAKKGLVLVKTVTLMIIATYNENMFPSVCVEAVEKLADYFKEKG 149
[Close]
BLAST of Profilin vs. TrEMBL
Match: A0A1S3KHC1 (Profilin OS=Lingula unguis OX=7574 GN=LOC106181909 PE=3 SV=1)

HSP 1 Score: 121.324 bits (303), Expect = 3.563e-28
Identity = 63/142 (44.37%), Postives = 94/142 (66.20%), Query Frame = 1 
Query:  982 SIYLMTVVSVFKNMNPLQNLITDALLRTGHVSNACLIDKNLDGKLLASTNGFTLSQDQVVXXXXXXXXXXXXRENDFYFGGRKFECIRADKESIYAKNGNSGVILMQTNQLIVLATYNDHMFPAVAVESVEKLCQYFKEKGK 1407
            S+Y M  +     MN LQNL+ DAL+ T HV+  C I +  D  + A + GFTL  DQ+  ++ +F +P   RE   YF  ++++C+RADK SIYAK+   G++L++T  L+++ATY D+M+P+V VE+ EKL  YFK+KGK
Sbjct:   27 SLYFMDAL----KMNQLQNLLHDALISTAHVAQ-CAIVRRKDCSVSACSVGFTLYTDQIQMLLDAFKNPPQTREEGLYFEDKQYKCVRADKNSIYAKSARKGLVLVKTTTLLLVATYTDNMYPSVCVEATEKLADYFKDKGK 163
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BLAST of Profilin vs. TrEMBL
Match: A0A3S1B639 (Profilin OS=Elysia chlorotica OX=188477 GN=EGW08_015229 PE=3 SV=1)

HSP 1 Score: 122.094 bits (305), Expect = 5.482e-28
Identity = 64/129 (49.61%), Postives = 88/129 (68.22%), Query Frame = 1 
Query: 1021 MNPLQNLITDALLRTGHVSNACLIDKNLDGKLLASTNGFTLSQDQVVXXXXXXXXXXXXRENDFYFGGRKFECIRADKESIYAKNGNSGVILMQTNQLIVLATYNDHMFPAVAVESVEKLCQYFKEKGK 1407
            MN L NL+ DAL+ T HV   C I +  DG + AS+ GF L  DQV  ++ +F +P   RE   YF  ++++C+RADK SIYAK G  G++L++T  L+++ATY + MFP+V VE+VEKL  YFKEKGK
Sbjct:   70 MNQLSNLLQDALICTDHVQQ-CAIIRRKDGNVRASSVGFNLYPDQVTLLLDAFKNPPQTREEGIYFDDKQYKCVRADKTSIYAKCGKRGLVLVKTMTLLIIATYTESMFPSVCVEAVEKLADYFKEKGK 197
[Close]
BLAST of Profilin vs. Ensembl Yeast
Match: PFY1 (Profilin; binds actin, phosphatidylinositol 4,5-bisphosphate, and polyproline regions; involved in cytoskeleton organization; required for normal timing of actin polymerization in response to thermal stress; protein abundance increases in response to DNA replication stress; highly conserved protein; human PFN1 (profilin 1) complements temperature sensitive pfy1 mutants, PFN1 mutations are a rare cause of ALS [Source:SGD;Acc:S000005648])

HSP 1 Score: 55.4546 bits (132), Expect = 7.635e-10
Identity = 35/116 (30.17%), Postives = 64/116 (55.17%), Query Frame = 1 
Query: 1045 TDALLRTGHVSNACLIDKNLDGKLLASTNGFTLSQDQVVXXXXXXXXXXXXRENDFYFGGRKFECIRADKESIYAKNGNSGVILMQTNQLIVLATYNDHMFPAVAVESVEKLCQYF 1392
            TD L+ TG V  A +  +  D  + A++ G +L  +++  I+  F +P+ ++ N  +  G+KF  +RAD  SIY ++   GV+ ++T Q +++A Y   +    A + VE+L  Y 
Sbjct:    7 TDNLIGTGKVDKAVIYSRAGDA-VWATSGGLSLQPNEIGEIVQGFDNPAGLQSNGLHIQGQKFMLLRADDRSIYGRHDAEGVVCVRTKQTVIIAHYPPTVQAGEATKIVEQLADYL 121
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BLAST of Profilin vs. Ensembl Nematostella
Match: EDO38706 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SC66])

HSP 1 Score: 83.9593 bits (206), Expect = 1.904e-19
Identity = 47/120 (39.17%), Postives = 75/120 (62.50%), Query Frame = 1 
Query: 1021 MNPLQNLITDALLRTGHVSNACLIDKNLDGKLLASTNGFTLSQDQVVXXXXXXXXXXXXRENDFYFGGRKFECIRADKESIYAKNGNSGVILMQTNQLIVLATYNDHMFPAVAVESVEKL 1380
            MN LQ+L+ D+L+ TGHV + C I +  D  L AST GF  + D + S++ +F   +  R +   F    +EC+RADK S+Y K+  +G++ ++T  LI++A Y+  M P++ VE+ EKL
Sbjct:    1 MNQLQSLLHDSLIATGHVKH-CAIIRRKDTSLRASTVGFNPTFDNMSSLVGAFGDSARTRMDGLKFEDVLYECVRADKFSVYGKHDKTGIVAIKTATLILVALYSQEMSPSICVEASEKL 119
[Close]
BLAST of Profilin vs. Ensembl Nematostella
Match: EDO40921 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S5R6])

HSP 1 Score: 51.6026 bits (122), Expect = 4.386e-8
Identity = 37/132 (28.03%), Postives = 64/132 (48.48%), Query Frame = 1 
Query: 1033 QNLITDALLRTGHVSNACLIDKNLDGKLLASTNGFTL--SQDQVVXXXXXXXXXXXXRENDFYFGG-----RKFECIRADK-ESIYAKNGNSGVILMQTNQLIVLATYNDHMFPAVAVESVEKLCQYFKEKG 1404
            Q  + ++LL T  V+ A +    L+G+  AS++GF +  S+ QV+    +         +  Y+ G      K+  IR D   S+Y + GN G + + T+Q +++  Y++ M P       EKL  YF+  G
Sbjct:    4 QQFVDESLLGTSQVAKASI--HGLNGERYASSSGFVVLPSEAQVLIAAITKD------PSPTYYKGVCLNRTKYFVIRVDPGHSLYCRKGNEGAVAVLTSQCLLIGAYSEGMTPGCCSAVTEKLADYFRVNG 127
[Close]
BLAST of Profilin vs. Planmine SMEST
Match: SMESG000020082.1 (SMESG000020082.1)

HSP 1 Score: 259.61 bits (662), Expect = 2.378e-83
Identity = 138/138 (100.00%), Postives = 138/138 (100.00%), Query Frame = 1 
Query:  994 MTVVSVFKNMNPLQNLITDALLRTGHVSNACLIDKNLDGKLLASTNGFTLSQDQVVXXXXXXXXXXXXRENDFYFGGRKFECIRADKESIYAKNGNSGVILMQTNQLIVLATYNDHMFPAVAVESVEKLCQYFKEKGK 1407
            MTVVSVFKNMNPLQNLITDALLRTGHVSNACLIDKNLDGKLLASTNGFTLSQDQVVSIIASFISPSSIRENDFYFGGRKFECIRADKESIYAKNGNSGVILMQTNQLIVLATYNDHMFPAVAVESVEKLCQYFKEKGK
Sbjct:    1 MTVVSVFKNMNPLQNLITDALLRTGHVSNACLIDKNLDGKLLASTNGFTLSQDQVVSIIASFISPSSIRENDFYFGGRKFECIRADKESIYAKNGNSGVILMQTNQLIVLATYNDHMFPAVAVESVEKLCQYFKEKGK 138
[Close]
BLAST of Profilin vs. Planmine SMEST
Match: SMESG000020082.1 (SMESG000020082.1)

HSP 1 Score: 241.891 bits (616), Expect = 1.346e-76
Identity = 129/129 (100.00%), Postives = 129/129 (100.00%), Query Frame = 1 
Query: 1021 MNPLQNLITDALLRTGHVSNACLIDKNLDGKLLASTNGFTLSQDQVVXXXXXXXXXXXXRENDFYFGGRKFECIRADKESIYAKNGNSGVILMQTNQLIVLATYNDHMFPAVAVESVEKLCQYFKEKGK 1407
            MNPLQNLITDALLRTGHVSNACLIDKNLDGKLLASTNGFTLSQDQVVSIIASFISPSSIRENDFYFGGRKFECIRADKESIYAKNGNSGVILMQTNQLIVLATYNDHMFPAVAVESVEKLCQYFKEKGK
Sbjct:    1 MNPLQNLITDALLRTGHVSNACLIDKNLDGKLLASTNGFTLSQDQVVSIIASFISPSSIRENDFYFGGRKFECIRADKESIYAKNGNSGVILMQTNQLIVLATYNDHMFPAVAVESVEKLCQYFKEKGK 129
[Close]
BLAST of Profilin vs. Planmine SMEST
Match: SMESG000020082.1 (SMESG000020082.1)

HSP 1 Score: 223.016 bits (567), Expect = 1.756e-69
Identity = 124/138 (89.86%), Postives = 124/138 (89.86%), Query Frame = 1 
Query:  994 MTVVSVFKNMNPLQNLITDALLRTGHVSNACLIDKNLDGKLLASTNGFTLSQDQVVXXXXXXXXXXXXRENDFYFGGRKFECIRADKESIYAKNGNSGVILMQTNQLIVLATYNDHMFPAVAVESVEKLCQYFKEKGK 1407
            MTVVSVFKNMNPLQNLITDALLRTGHVSNACLIDKNLD              DQVVSIIASFISPSSIRENDFYFGGRKFECIRADKESIYAKNGNSGVILMQTNQLIVLATYNDHMFPAVAVESVEKLCQYFKEKGK
Sbjct:    1 MTVVSVFKNMNPLQNLITDALLRTGHVSNACLIDKNLD--------------DQVVSIIASFISPSSIRENDFYFGGRKFECIRADKESIYAKNGNSGVILMQTNQLIVLATYNDHMFPAVAVESVEKLCQYFKEKGK 124
[Close]
BLAST of Profilin vs. Planmine SMEST
Match: SMESG000020082.1 (SMESG000020082.1)

HSP 1 Score: 205.297 bits (521), Expect = 6.287e-63
Identity = 115/129 (89.15%), Postives = 115/129 (89.15%), Query Frame = 1 
Query: 1021 MNPLQNLITDALLRTGHVSNACLIDKNLDGKLLASTNGFTLSQDQVVXXXXXXXXXXXXRENDFYFGGRKFECIRADKESIYAKNGNSGVILMQTNQLIVLATYNDHMFPAVAVESVEKLCQYFKEKGK 1407
            MNPLQNLITDALLRTGHVSNACLIDKNLD              DQVVSIIASFISPSSIRENDFYFGGRKFECIRADKESIYAKNGNSGVILMQTNQLIVLATYNDHMFPAVAVESVEKLCQYFKEKGK
Sbjct:    1 MNPLQNLITDALLRTGHVSNACLIDKNLD--------------DQVVSIIASFISPSSIRENDFYFGGRKFECIRADKESIYAKNGNSGVILMQTNQLIVLATYNDHMFPAVAVESVEKLCQYFKEKGK 115
[Close]
BLAST of Profilin vs. Planmine SMEST
Match: SMESG000020071.1 (SMESG000020071.1)

HSP 1 Score: 86.6557 bits (213), Expect = 9.966e-31
Identity = 54/54 (100.00%), Postives = 54/54 (100.00%), Query Frame = -3 
Query: 1880 GSPVILPDEIDRSSYPPSKXXXXXXXXXXXXXPDYNHESTPNFVTMTTCSYRGP 2041
            GSPVILPDEIDRSSYPPSKPLILPHEKPPLPPPDYNHESTPNFVTMTTCSYRGP
Sbjct: 1279 GSPVILPDEIDRSSYPPSKPLILPHEKPPLPPPDYNHESTPNFVTMTTCSYRGP 1332

HSP 2 Score: 67.3958 bits (163), Expect = 9.966e-31
Identity = 28/28 (100.00%), Postives = 28/28 (100.00%), Query Frame = -2 
Query: 1800 TSSFGRQQTPSIRSSPHSHDRFPHGVFG 1883
            TSSFGRQQTPSIRSSPHSHDRFPHGVFG
Sbjct: 1347 TSSFGRQQTPSIRSSPHSHDRFPHGVFG 1374
The following BLAST results are available for this feature:
BLAST of Profilin vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 1
Match NameE-valueIdentityDescription
PFN46.793e-1735.65profilin family member 4 [Source:HGNC Symbol;Acc:H... [more]
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BLAST of Profilin vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Profilin vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
chic8.336e-827.50gene:FBgn0000308 transcript:FBtr0079236[more]
chic8.336e-827.50gene:FBgn0000308 transcript:FBtr0309213[more]
chic8.336e-827.50gene:FBgn0000308 transcript:FBtr0079235[more]
chic8.336e-827.50gene:FBgn0000308 transcript:FBtr0309212[more]
chic8.336e-827.50gene:FBgn0000308 transcript:FBtr0079234[more]
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BLAST of Profilin vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 1
Match NameE-valueIdentityDescription
si:ch211-175f11.53.495e-2136.92si:ch211-175f11.5 [Source:ZFIN;Acc:ZDB-GENE-131121... [more]
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BLAST of Profilin vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 1
Match NameE-valueIdentityDescription
PFN48.647e-2140.16profilin family member 4 [Source:NCBI gene;Acc:100... [more]
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BLAST of Profilin vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 3
Match NameE-valueIdentityDescription
Pfn45.914e-1838.26profilin family, member 4 [Source:MGI Symbol;Acc:M... [more]
Pfn45.914e-1838.26profilin family, member 4 [Source:MGI Symbol;Acc:M... [more]
Pfn43.987e-1537.27profilin family, member 4 [Source:MGI Symbol;Acc:M... [more]
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BLAST of Profilin vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q9D6I3|PROF4_MOUSE4.137e-1738.26Profilin-4 OS=Mus musculus OX=10090 GN=Pfn4 PE=1 S... [more]
sp|Q8NHR9|PROF4_HUMAN3.262e-1635.65Profilin-4 OS=Homo sapiens OX=9606 GN=PFN4 PE=1 SV... [more]
sp|Q2NKT1|PROF4_BOVIN9.385e-1637.39Profilin-4 OS=Bos taurus OX=9913 GN=PFN4 PE=2 SV=1[more]
sp|Q5IRJ7|PROF4_RAT4.945e-1435.65Profilin-4 OS=Rattus norvegicus OX=10116 GN=Pfn4 P... [more]
sp|P19984|PROF2_ACACA9.743e-1433.87Profilin-2 OS=Acanthamoeba castellanii OX=5755 PE=... [more]
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BLAST of Profilin vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A2C9KMD02.572e-2848.44Profilin OS=Biomphalaria glabrata OX=6526 GN=10606... [more]
A0A2C9KM562.605e-2848.44Profilin OS=Biomphalaria glabrata OX=6526 GN=10606... [more]
A0A2C9KM573.469e-2848.44Profilin OS=Biomphalaria glabrata OX=6526 GN=10606... [more]
A0A1S3KHC13.563e-2844.37Profilin OS=Lingula unguis OX=7574 GN=LOC106181909... [more]
A0A3S1B6395.482e-2849.61Profilin OS=Elysia chlorotica OX=188477 GN=EGW08_0... [more]
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BLAST of Profilin vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Profilin vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Profilin vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 1
Match NameE-valueIdentityDescription
PFY17.635e-1030.17Profilin; binds actin, phosphatidylinositol 4,5-bi... [more]
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BLAST of Profilin vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 2
Match NameE-valueIdentityDescription
EDO387061.904e-1939.17Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO409214.386e-828.03Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Profilin vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Profilin vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000020082.12.378e-83100.00SMESG000020082.1[more]
SMESG000020082.11.346e-76100.00SMESG000020082.1[more]
SMESG000020082.11.756e-6989.86SMESG000020082.1[more]
SMESG000020082.16.287e-6389.15SMESG000020082.1[more]
SMESG000020071.19.966e-31100.00SMESG000020071.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30008903 ID=SMED30008903|Name=Profilin|organism=Schmidtea mediterranea sexual|type=transcript|length=2067bp
GTTTTATTATTTTAAATAAGAAAAATTTCAATATATAATAATAATATTAA
ATGGCAGGCGCTAAAATGGTTGACAAAACTAATATGTCATTGGATGATAT
AATTAAGATGGATAGAAAAAATATAAAAACCAAACCTGGTTTTATAAAAA
ATAAAAATTCTTTGGCTAGAAATGCAGTTAGGAAAGCCAAAAATTCCTTT
ATAAACAAAAAGAATATAAACTTACCTCAAAGAAATATGAATATTTCTGA
TAAACGTCAAGATTGATTCCCAGAAATATACAGAAACCAACAAGAAATTG
TAAGTAATTTGCGGATGGAAAGACGGTTAATAAGATTTGTATTAAGCTTA
TGTCCCCAGACAAAATCAATTCTTAAATACTAACTATAAATCAAGAATAA
GTAATCGTATTAATACAAAGGTTATCAATTCAGCACCGGCATTTAGAATA
ACAACGAATAATGAACGTTATCAATCAAGCAGTATGGATAATTATTAACT
AACCATTAAGATTGATAATCTAATAGACAGAGGAAGACCAAACACGAGAC
CGACATATAAAAGATTTCCAAATGCTAATAATAGCGAAACTTCATTTTCA
AATAATAGTCGAGAACAAATTATTAACTTCTCTCGAAATGATCGGCGTCC
AACTGAGAGAATTGATCACTATCAATTTGCACGTCGAAATAACAGTGGAT
TCGTTAACAGAAATTCAGCTTTTGCAAGAGATAGAGAATATGAAGTTATG
GCTAGAGCTTTAATCGAAGCTCATAAGGAATCGCGATATTCTATATCTCA
AAGACGATATAGTGGACCTATGGAAAGTCGTGGATATCCGTACCGTCGTT
GATATTTAATGTTTTGTAGCAATATAATTTATGTTTGTTAAAATTAAATC
TTTTTCGAAAGTCAATTGATTTTATTGCGCCGTTTAATTAATTGAAACAA
AAATAGTATCCAATTATAACGACGTTGCTATAGTATTTATTTGATGACAG
TCGTGTCAGTTTTTAAAAATATGAATCCATTACAAAATTTGATAACAGAT
GCACTTCTTCGTACTGGTCATGTCAGCAATGCATGTCTCATTGATAAGAA
CTTAGATGGTAAATTATTAGCTTCAACAAATGGATTTACGTTATCTCAAG
ATCAAGTTGTTTCAATAATAGCATCATTTATATCACCAAGTTCAATTAGG
GAAAACGATTTCTATTTCGGTGGTCGTAAATTTGAATGTATTCGAGCAGA
TAAAGAATCGATTTATGCCAAAAATGGAAACAGTGGAGTTATTTTAATGC
AAACTAATCAATTGATAGTCCTGGCCACTTACAATGATCATATGTTTCCT
GCAGTAGCTGTCGAATCTGTTGAAAAATTATGCCAATATTTTAAAGAAAA
AGGAAAATAATTTAAATATAATTTATGGCTAATCATGCTTTTTTAAATTT
TTGTCATTTGCATACGAATCAATTAAATTAATGTTTATTATTAATAATAA
ATAAACAATAGTACAAATATTGTTATTGGAAAAAATCCATTTCAATTACC
AAACTATTTACAAATTCCAATAGAAAAAGAAGCTTAGTAGAAACAACTGA
ATTTTATAGAACTACAGTAAGTTGTAAATTGTTAATTAATTGTCTAGTTT
TTCGGCAGTCAACTGGTATGAGTTTGATGTAACCACTATTCAATAGGATT
AGTAATGTTTACCAGCAGTTGGCATTAGTCAGCATATGAAATGATCGACA
TGCTGATAGACATTTTTGTCAATTTAATAGAACTCGGCTACTTCTGTCAT
CCGAAAACACCATGAGGAAATCTGTCATGTGAATGCGGTGAACTCCGTAT
CGATGGAGTTTGTTGACGACCAAACGACGAGGTCCTCTGTAAGAACAAGT
AGTCATTGTTACAAAATTTGGTGTTGATTCATGATTGTAATCTGGTGGAG
GCAATGGAGGTTTCTCGTGGGGGAGAATCAGTGGCTTTGATGGTGGATAT
GATGATCGATCAATTTCATCTGGAAGAATGACTGGAGAACCTAATTTAAA
ATATAATTCAATCGCAA
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protein sequence of SMED30008903-orf-1

>SMED30008903-orf-1 ID=SMED30008903-orf-1|Name=SMED30008903-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=139bp
MTVVSVFKNMNPLQNLITDALLRTGHVSNACLIDKNLDGKLLASTNGFTL
SQDQVVSIIASFISPSSIRENDFYFGGRKFECIRADKESIYAKNGNSGVI
LMQTNQLIVLATYNDHMFPAVAVESVEKLCQYFKEKGK*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000099neuron
PLANA:0000418head
PLANA:0002109X1 cell
Vocabulary: INTERPRO
TermDefinition
IPR036140PFN_sf
IPR008465DAG1_C
IPR005455PFN
Vocabulary: cellular component
TermDefinition
GO:0016010dystrophin-associated glycoprotein complex
Vocabulary: biological process
TermDefinition
GO:0007016cytoskeletal anchoring at plasma membrane
Vocabulary: molecular function
TermDefinition
GO:0003779actin binding
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR005455ProfilinSMARTSM00392prof_2coord: 14..138
e-value: 1.9E-8
score: 44.1
IPR005455ProfilinPFAMPF00235Profilincoord: 14..137
e-value: 4.6E-29
score: 101.3
IPR005455ProfilinPANTHERPTHR11604PROFILINcoord: 10..137
IPR005455ProfilinCDDcd00148PROFcoord: 14..137
e-value: 2.06291E-27
score: 96.6256
NoneNo IPR availableGENE3DG3DSA:3.30.450.30coord: 13..137
e-value: 4.1E-30
score: 106.4
NoneNo IPR availablePANTHERPTHR11604:SF2PROFILIN-4coord: 10..137
IPR036140Profilin superfamilySUPERFAMILYSSF55770Profilin (actin-binding protein)coord: 14..137