Pre-mRNA-processing ATP-dependent RNA helicase PRP5

Overview
NamePre-mRNA-processing ATP-dependent RNA helicase PRP5
Smed IDSMED30008892
Length (bp)3155
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Pre-mRNA-processing ATP-dependent RNA helicase PRP5 (SMED30008892) t-SNE clustered cells

Violin plots show distribution of expression levels for Pre-mRNA-processing ATP-dependent RNA helicase PRP5 (SMED30008892) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Pre-mRNA-processing ATP-dependent RNA helicase PRP5 (SMED30008892) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Pre-mRNA-processing ATP-dependent RNA helicase PRP5 (SMED30008892) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30008892

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 5

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
X1 cellSMED30008892SMESG000075674.1 SmedASXL_011383SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015		FACS sorted cell population asexual adult RNA-sequencing evidence
X2 cellSMED30008892SMESG000075674.1 SmedASXL_011383SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015		FACS sorted cell population asexual adult RNA-sequencing evidence
nervous systemSMED30008892SMESG000075674.1 dd_Smed_v4_6143_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30008892SMESG000075674.1 dd_Smed_v4_6143_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30008892SMESG000075674.1 dd_Smed_v4_6143_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Pre-mRNA-processing ATP-dependent RNA helicase PRP5 vs. Ensembl Human
Match: DDX46 (DEAD-box helicase 46 [Source:HGNC Symbol;Acc:HGNC:18681])

HSP 1 Score: 550.436 bits (1417), Expect = 1.067e-178
Identity = 320/798 (40.10%), Postives = 471/798 (59.02%), Query Frame = 2 
Query:  656 DVDSIDAYMSTLIKTVKD----------------------------------PSIAKIGEFTDDHIEDTDEYHQTVEPETLESITQALFEEKKQKLPDVNHDKVYYRKYDFNLYKEVPEISKMTTKEVKELRRSM-AIVVKGKECPKPITKWSHAIVSMKILNALKYNKMNEPTPIQSQTIPAIMSGKDVIGIAKTGSGKTLSYLLPLIRHIHNQPNVTVGEGPIAIVLCPTRELSIQIHQEIEKI--TYALRDVNCGCIYGGADTAQQISRLKRGVEIVVGTPGRIIDIMATNGGRNLSLSRCTFIVLDEADRMFDMGFEPQVMAIISRIRPDRQTVMFSATFPRRIEAVAKKIMKEPIEVRVDGGNKVCTDVVQHVYLLDENDKFLKLVELLSEFKYRGKSLVFVETQETAQILSSNLTHQGFEVSMIHGGLTQEKREEGMFNFKSGTVPILIATSIAARGLDVNDLMMVVNYDCPNHYEDYVHRCGRTGRAGNKGYSYTFVTSDQEVMIGNLIKALKENGQEIPGELTEAYARYTERMVLEGKTIKAPSGFRGHGYKFDAAE-AMKEKGKKLQELFKYCPEEITEEDEAVLEEMQLTSQRTSHQL---NANPLVPQIPSYEAQNHAKA--AHQMAMKLNMKLD-----------STGSVVEPSGDIAPS-----------------------------------------SREEIPINNLPANIRYLLTTRDLRTNLSENFDVALTVKGVFMAPKDIKKLEQIGEKPLHLVLESDSPINIRSARNEICRVVKEAM 2764
            ++D +DAYM  + + VK                                    S  K GE  ++  +D  EY    E   L++       ++++ L  V+H K+ Y  +  N Y EVPE++KM+ +EV   R  M  I VKGK CPKPI  W    +SMKILN+LK +   +PTPIQ+Q IPAIMSG+D+IGIAKTGSGKT+++LLP+ RHI +Q ++  GEGPIA+++ PTREL++QI +E +K   T  LR V   C+YGG   ++QI+ LKRG EI+V TPGR+ID++A N GR  +L R T++VLDEADRMFDMGFEPQVM I+  +RPDRQTVMFSATFPR +EA+A++I+ +PIEV+V G + VC+DV Q V +++E  KFLKL+ELL  ++  G  ++FV+ QE A  L  +L    +    +HGG+ Q  R+  + +FK+GT  +L+ATS+AARGLDV  L++VVNY CPNHYEDYVHR GRTGRAGNKGY+YTF+T DQ    G++IKAL+ +G  +P +L + ++ + ++   EGK IK  SGF G G+KFD  E A+  + KKLQ+      ++  +ED AV  + Q+ S   S +     A P    +P+  A N  K   A ++A+++N + +           +T +++     +AP+                                           EE+ IN+ P   R+ +T+++    +SE  + A+T++G +  P    K  + GE+ ++L +ES + + ++ A+ EI R++KE +
Sbjct:  224 ELDPLDAYMEEVKEEVKKFNMRSVKGGGGNEKKSGPTVTKVVTVVTTKKAVVDSDKKKGELMEND-QDAMEYSSEEEEVDLQTALTGYQTKQRKLLEPVDHGKIEYEPFRKNFYVEVPELAKMSQEEVNVFRLEMEGITVKGKGCPKPIKSWVQCGISMKILNSLKKHGYEKPTPIQTQAIPAIMSGRDLIGIAKTGSGKTIAFLLPMFRHIMDQRSLEEGEGPIAVIMTPTRELALQITKECKKFSKTLGLRVV---CVYGGTGISEQIAELKRGAEIIVCTPGRMIDMLAANSGRVTNLRRVTYVVLDEADRMFDMGFEPQVMRIVDNVRPDRQTVMFSATFPRAMEALARRILSKPIEVQVGGRSVVCSDVEQQVIVIEEEKKFLKLLELLGHYQESGSVIIFVDKQEHADGLLKDLMRASYPCMSLHGGIDQYDRDSIINDFKNGTCKLLVATSVAARGLDVKHLILVVNYSCPNHYEDYVHRAGRTGRAGNKGYAYTFITEDQARYAGDIIKALELSGTAVPPDLEKLWSDFKDQQKAEGKIIKKSSGFSGKGFKFDETEQALANERKKLQKA-ALGLQDSDDEDAAVDIDEQIESMFNSKKRVKDMAAPGTSSVPAPTAGNAEKLEIAKRLALRINAQKNLGIESQDVMQQATNAILRGGTILAPTVSAKTIAEQLAEKINAKLNYVPLEKQEEERQDGGQNESFKRYEEELEINDFPQTARWKVTSKEALQRISEYSEAAITIRGTYFPP---GKEPKEGERKIYLAIESANELAVQKAKAEITRLIKEEL 1013
[Close]
BLAST of Pre-mRNA-processing ATP-dependent RNA helicase PRP5 vs. Ensembl Human
Match: DDX46 (DEAD-box helicase 46 [Source:HGNC Symbol;Acc:HGNC:18681])

HSP 1 Score: 550.051 bits (1416), Expect = 1.385e-178
Identity = 320/799 (40.05%), Postives = 471/799 (58.95%), Query Frame = 2 
Query:  656 DVDSIDAYMSTLIKTVKD----------------------------------PSIAKIGEFTDDHIEDTDEYHQTVEPETLESITQALFEEKKQKLPDVNHDKVYYRKYDFNLYKEVPEISKMTTKEVKELRRSM-AIVVKGKECPKPITKWSHAIVSMKILNALKYNKMNEPTPIQSQTIPAIMSGKDVIGIAKTGSGKTLSYLLPLIRHIHNQPNVTVGEGPIAIVLCPTRELSIQIHQEIEKI--TYALRDVNCGCIYGGADTAQQISRLKRGVEIVVGTPGRIIDIMATNGGRNLSLSRCTFIVLDEADRMFDMGFEPQVMAIISRIRPDRQTVMFSATFPRRIEAVAKKIMKEPIEVRVDGGNKVCTDVVQHVYLLDENDKFLKLVELLSEFKYRGKSLVFVETQETAQILSSNLTHQGFEVSMIHGGLTQEKREEGMFNFKSGTVPILIATSIAARGLDVNDLMMVVNYDCPNHYEDYVHRCGRTGRAGNKGYSYTFVTSDQEVMIGNLIKALKENGQEIPGELTEAYARYTERMVLEGKTIKAPSGFRGHGYKFDAAE-AMKEKGKKLQELFKYCPEEITEEDEAVLEEMQLTSQRTSHQL---NANPLVPQIPSYEAQNHAKA--AHQMAMKLNMKLD------------STGSVVEPSGDIAPS-----------------------------------------SREEIPINNLPANIRYLLTTRDLRTNLSENFDVALTVKGVFMAPKDIKKLEQIGEKPLHLVLESDSPINIRSARNEICRVVKEAM 2764
            ++D +DAYM  + + VK                                    S  K GE  ++  +D  EY    E   L++       ++++ L  V+H K+ Y  +  N Y EVPE++KM+ +EV   R  M  I VKGK CPKPI  W    +SMKILN+LK +   +PTPIQ+Q IPAIMSG+D+IGIAKTGSGKT+++LLP+ RHI +Q ++  GEGPIA+++ PTREL++QI +E +K   T  LR V   C+YGG   ++QI+ LKRG EI+V TPGR+ID++A N GR  +L R T++VLDEADRMFDMGFEPQVM I+  +RPDRQTVMFSATFPR +EA+A++I+ +PIEV+V G + VC+DV Q V +++E  KFLKL+ELL  ++  G  ++FV+ QE A  L  +L    +    +HGG+ Q  R+  + +FK+GT  +L+ATS+AARGLDV  L++VVNY CPNHYEDYVHR GRTGRAGNKGY+YTF+T DQ    G++IKAL+ +G  +P +L + ++ + ++   EGK IK  SGF G G+KFD  E A+  + KKLQ+      ++  +ED AV  + Q+ S   S +     A P    +P+  A N  K   A ++A+++N + +            +T +++     +AP+                                           EE+ IN+ P   R+ +T+++    +SE  + A+T++G +  P    K  + GE+ ++L +ES + + ++ A+ EI R++KE +
Sbjct:  224 ELDPLDAYMEEVKEEVKKFNMRSVKGGGGNEKKSGPTVTKVVTVVTTKKAVVDSDKKKGELMEND-QDAMEYSSEEEEVDLQTALTGYQTKQRKLLEPVDHGKIEYEPFRKNFYVEVPELAKMSQEEVNVFRLEMEGITVKGKGCPKPIKSWVQCGISMKILNSLKKHGYEKPTPIQTQAIPAIMSGRDLIGIAKTGSGKTIAFLLPMFRHIMDQRSLEEGEGPIAVIMTPTRELALQITKECKKFSKTLGLRVV---CVYGGTGISEQIAELKRGAEIIVCTPGRMIDMLAANSGRVTNLRRVTYVVLDEADRMFDMGFEPQVMRIVDNVRPDRQTVMFSATFPRAMEALARRILSKPIEVQVGGRSVVCSDVEQQVIVIEEEKKFLKLLELLGHYQESGSVIIFVDKQEHADGLLKDLMRASYPCMSLHGGIDQYDRDSIINDFKNGTCKLLVATSVAARGLDVKHLILVVNYSCPNHYEDYVHRAGRTGRAGNKGYAYTFITEDQARYAGDIIKALELSGTAVPPDLEKLWSDFKDQQKAEGKIIKKSSGFSGKGFKFDETEQALANERKKLQKA-ALGLQDSDDEDAAVDIDEQIESMFNSKKRVKDMAAPGTSSVPAPTAGNAEKLEIAKRLALRINAQKNLGIESQVDVMQQATNAILRGGTILAPTVSAKTIAEQLAEKINAKLNYVPLEKQEEERQDGGQNESFKRYEEELEINDFPQTARWKVTSKEALQRISEYSEAAITIRGTYFPP---GKEPKEGERKIYLAIESANELAVQKAKAEITRLIKEEL 1014
[Close]
BLAST of Pre-mRNA-processing ATP-dependent RNA helicase PRP5 vs. Ensembl Human
Match: DDX17 (DEAD-box helicase 17 [Source:HGNC Symbol;Acc:HGNC:2740])

HSP 1 Score: 367.466 bits (942), Expect = 1.042e-112
Identity = 189/422 (44.79%), Postives = 269/422 (63.74%), Query Frame = 2 
Query:  875 KYDFNLYKEVPEISKMTTKEVKELRRSMAIVVKGKE-CPKPITKWSHAIVSMKILNALKYNKMNEPTPIQSQTIPAIMSGKDVIGIAKTGSGKTLSYLLPLIRHIHNQPNVTVGEGPIAIVLCPTRELSIQIHQEIEKITYALRDVNCGCIYGGADTAQQISRLKRGVEIVVGTPGRIIDIMATNGGRNLSLSRCTFIVLDEADRMFDMGFEPQVMAIISRIRPDRQTVMFSATFPRRIEAVAKKIMKEPIEVRVDGGN---KVCTDVVQHVYLLDENDKFLKLVELLSEF--KYRGKSLVFVETQETAQILSSNLTHQGFEVSMIHGGLTQEKREEGMFNFKSGTVPILIATSIAARGLDVNDLMMVVNYDCPNHYEDYVHRCGRTGRAGNKGYSYTFVTSDQEVMIGNLIKALKENGQEI 2122
            K++ N Y E PE++++T  EV ELRR   I V+G + CPKP+  + HA     +++ L      EPTPIQ Q  P  +SG+D++GIA+TGSGKTL+YLLP I HI++QP +  G+GPI +VL PTREL+ Q+ Q  +      R +   CIYGGA    QI  L+RGVEI + TPGR+ID + +      +L RCT++VLDEADRM DMGFEPQ+  I+ +IRPDRQT+M+SAT+P+ +  +A+  +++  ++ V  GN       +++Q V +  E++K  KL++L+ E   +   K+++FVET+     L+  +   G+    IHG  +Q +R+  +  F+SG  PILIAT +A+RGLDV D+  V+NYD PN  EDYVHR GRT R+ NKG +YTF T         LIK L+E  Q I
Sbjct:  129 KFEKNFYVEHPEVARLTPYEVDELRRKKEITVRGGDVCPKPVFAFHHANFPQYVMDVLMDQHFTEPTPIQCQGFPLALSGRDMVGIAQTGSGKTLAYLLPAIVHINHQPYLERGDGPICLVLAPTRELAQQVQQVADDYGKCSR-LKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLESG---KTNLRRCTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAEDFLRDYTQINV--GNLELSANHNILQIVDVCMESEKDHKLIQLMEEIMAEKENKTIIFVETKRRCDDLTRRMRRDGWPAMCIHGDKSQPERDWVLNEFRSGKAPILIATDVASRGLDVEDVKFVINYDYPNSSEDYVHRIGRTARSTNKGTAYTFFTPGNLKQARELIKVLEEANQAI 544
[Close]
BLAST of Pre-mRNA-processing ATP-dependent RNA helicase PRP5 vs. Ensembl Human
Match: DDX17 (DEAD-box helicase 17 [Source:HGNC Symbol;Acc:HGNC:2740])

HSP 1 Score: 367.466 bits (942), Expect = 1.097e-112
Identity = 189/422 (44.79%), Postives = 269/422 (63.74%), Query Frame = 2 
Query:  875 KYDFNLYKEVPEISKMTTKEVKELRRSMAIVVKGKE-CPKPITKWSHAIVSMKILNALKYNKMNEPTPIQSQTIPAIMSGKDVIGIAKTGSGKTLSYLLPLIRHIHNQPNVTVGEGPIAIVLCPTRELSIQIHQEIEKITYALRDVNCGCIYGGADTAQQISRLKRGVEIVVGTPGRIIDIMATNGGRNLSLSRCTFIVLDEADRMFDMGFEPQVMAIISRIRPDRQTVMFSATFPRRIEAVAKKIMKEPIEVRVDGGN---KVCTDVVQHVYLLDENDKFLKLVELLSEF--KYRGKSLVFVETQETAQILSSNLTHQGFEVSMIHGGLTQEKREEGMFNFKSGTVPILIATSIAARGLDVNDLMMVVNYDCPNHYEDYVHRCGRTGRAGNKGYSYTFVTSDQEVMIGNLIKALKENGQEI 2122
            K++ N Y E PE++++T  EV ELRR   I V+G + CPKP+  + HA     +++ L      EPTPIQ Q  P  +SG+D++GIA+TGSGKTL+YLLP I HI++QP +  G+GPI +VL PTREL+ Q+ Q  +      R +   CIYGGA    QI  L+RGVEI + TPGR+ID + +      +L RCT++VLDEADRM DMGFEPQ+  I+ +IRPDRQT+M+SAT+P+ +  +A+  +++  ++ V  GN       +++Q V +  E++K  KL++L+ E   +   K+++FVET+     L+  +   G+    IHG  +Q +R+  +  F+SG  PILIAT +A+RGLDV D+  V+NYD PN  EDYVHR GRT R+ NKG +YTF T         LIK L+E  Q I
Sbjct:  129 KFEKNFYVEHPEVARLTPYEVDELRRKKEITVRGGDVCPKPVFAFHHANFPQYVMDVLMDQHFTEPTPIQCQGFPLALSGRDMVGIAQTGSGKTLAYLLPAIVHINHQPYLERGDGPICLVLAPTRELAQQVQQVADDYGKCSR-LKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLESG---KTNLRRCTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAEDFLRDYTQINV--GNLELSANHNILQIVDVCMESEKDHKLIQLMEEIMAEKENKTIIFVETKRRCDDLTRRMRRDGWPAMCIHGDKSQPERDWVLNEFRSGKAPILIATDVASRGLDVEDVKFVINYDYPNSSEDYVHRIGRTARSTNKGTAYTFFTPGNLKQARELIKVLEEANQAI 544
[Close]
BLAST of Pre-mRNA-processing ATP-dependent RNA helicase PRP5 vs. Ensembl Human
Match: DDX17 (DEAD-box helicase 17 [Source:HGNC Symbol;Acc:HGNC:2740])

HSP 1 Score: 367.466 bits (942), Expect = 1.097e-112
Identity = 189/422 (44.79%), Postives = 269/422 (63.74%), Query Frame = 2 
Query:  875 KYDFNLYKEVPEISKMTTKEVKELRRSMAIVVKGKE-CPKPITKWSHAIVSMKILNALKYNKMNEPTPIQSQTIPAIMSGKDVIGIAKTGSGKTLSYLLPLIRHIHNQPNVTVGEGPIAIVLCPTRELSIQIHQEIEKITYALRDVNCGCIYGGADTAQQISRLKRGVEIVVGTPGRIIDIMATNGGRNLSLSRCTFIVLDEADRMFDMGFEPQVMAIISRIRPDRQTVMFSATFPRRIEAVAKKIMKEPIEVRVDGGN---KVCTDVVQHVYLLDENDKFLKLVELLSEF--KYRGKSLVFVETQETAQILSSNLTHQGFEVSMIHGGLTQEKREEGMFNFKSGTVPILIATSIAARGLDVNDLMMVVNYDCPNHYEDYVHRCGRTGRAGNKGYSYTFVTSDQEVMIGNLIKALKENGQEI 2122
            K++ N Y E PE++++T  EV ELRR   I V+G + CPKP+  + HA     +++ L      EPTPIQ Q  P  +SG+D++GIA+TGSGKTL+YLLP I HI++QP +  G+GPI +VL PTREL+ Q+ Q  +      R +   CIYGGA    QI  L+RGVEI + TPGR+ID + +      +L RCT++VLDEADRM DMGFEPQ+  I+ +IRPDRQT+M+SAT+P+ +  +A+  +++  ++ V  GN       +++Q V +  E++K  KL++L+ E   +   K+++FVET+     L+  +   G+    IHG  +Q +R+  +  F+SG  PILIAT +A+RGLDV D+  V+NYD PN  EDYVHR GRT R+ NKG +YTF T         LIK L+E  Q I
Sbjct:  129 KFEKNFYVEHPEVARLTPYEVDELRRKKEITVRGGDVCPKPVFAFHHANFPQYVMDVLMDQHFTEPTPIQCQGFPLALSGRDMVGIAQTGSGKTLAYLLPAIVHINHQPYLERGDGPICLVLAPTRELAQQVQQVADDYGKCSR-LKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLESG---KTNLRRCTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAEDFLRDYTQINV--GNLELSANHNILQIVDVCMESEKDHKLIQLMEEIMAEKENKTIIFVETKRRCDDLTRRMRRDGWPAMCIHGDKSQPERDWVLNEFRSGKAPILIATDVASRGLDVEDVKFVINYDYPNSSEDYVHRIGRTARSTNKGTAYTFFTPGNLKQARELIKVLEEANQAI 544
[Close]
BLAST of Pre-mRNA-processing ATP-dependent RNA helicase PRP5 vs. Ensembl Celegans
Match: F53H1.1 (pep chromosome:WBcel235:IV:1297222:1309652:-1 gene:WBGene00018776.1 transcript:F53H1.1a.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:F53H1.1)

HSP 1 Score: 557.37 bits (1435), Expect = 0.000e+0
Identity = 300/739 (40.60%), Postives = 444/739 (60.08%), Query Frame = 2 
Query:  749 IEDTDEYHQTVEPETLESITQALFEEKKQKLPDVNHDKVYYRKYDFNLYKEVPEISKMTTKEVKELRRSM-AIVVKGKECPKPITKWSHAIVSMKILNALKYNKMNEPTPIQSQTIPAIMSGKDVIGIAKTGSGKTLSYLLPLIRHIHNQPNVTVGEGPIAIVLCPTRELSIQIHQEIEKITYALRDVNCGCIYGGADTAQQISRLKRGVEIVVGTPGRIIDIMATNGGRNLSLSRCTFIVLDEADRMFDMGFEPQVMAIISRIRPDRQTVMFSATFPRRIEAVAKKIMKEPIEVRVDGGNKVCTDVVQHVYLLDENDKFLKLVELLSEFKYRGKSLVFVETQETAQILSSNLTHQGF-EVSMIHGGLTQEKREEGMFNFKSGTVPILIATSIAARGLDVNDLMMVVNYDCPNHYEDYVHRCGRTGRAGNKGYSYTFVTSD-QEVMIGNLIKALKENGQEIPGELTEAYARYTERMVLEGKTIK-APSGFRGHGYKFDAAEAMKEKGKKLQELFKYCPEEITEEDEAVLEEMQLTSQRTSHQLNANPLV--PQIPSYEAQNH---AKAAHQMAMK---LNMKLDSTGSVVEP--------------------------------------------SGDIAPSSRE---------EIPINNLPANIRYLLTTRDLRTNLSENFDVALTVKGVFMAPKDIKKLEQIGEKPLHLVLESDSPINIRSARNEICRVVKEAMKK 2770
            +E+ D     ++   +E+   +L   K + L   +H KVYYRK+  N Y E  EI +MT  EVK  R  + +I VKG +CPKPI  W+   V++K++N LK  + ++PT IQ+Q IP+IMSG+DVIGIAKTGSGKTL++LLP+ RHI +QP +  G+GPIA++L PTREL++Q ++E  K    L  +   C YGG   ++QI+ LKRG EIVV TPGR+ID++A N G+  +L R T++VLDEADRMFD GFEPQ+M +++ IRPD+QTV+FSATFPR +EA+A+K++ +P+E+ V G + VC+D+ Q+  +  E+ KFLKL+ELL  +   G S+VFV+ QE A  +   L   G+  V+ +HGG+ Q  R+  + +FK+G + +L+ATS+AARGLDV +L++VVNYDCPNHYEDYVHR GRTGRAG KGY+YTFV  + QE M G + +A +  G + P +L   + R+   M  EGK +K    GF G GYK+D  EA  +  KK      +  E   ++D+ + E++    +     ++  P    P   S  A+N     K A Q  +K   L+ +L     VV+P                                             G+ AP+ ++         E  IN+ P  +RY + +R+   +++E  +V ++V+GV + P    K  + GE+ LHL+LE+ S  N+++A+ EI R++KEA ++
Sbjct:  221 LENEDNMDMVIDDFDIETAAASLCH-KGRMLAQTDHSKVYYRKFKKNFYIETEEIRRMTKAEVKAYREELDSITVKGIDCPKPIKTWAQCGVNLKMMNVLKKFEYSKPTSIQAQAIPSIMSGRDVIGIAKTGSGKTLAFLLPMFRHILDQPELEEGDGPIAVILAPTRELAMQTYKEANKFAKPL-GLKVACTYGGVGISEQIADLKRGAEIVVCTPGRMIDVLAANSGKVTNLRRVTYLVLDEADRMFDKGFEPQIMKVVNNIRPDKQTVLFSATFPRHMEALARKVLDKPVEILVGGKSVVCSDITQNAVICAEHQKFLKLLELLGMYYEEGSSIVFVDKQEKADDIVDQLMRTGYNSVAPLHGGIDQHDRDSSIADFKTGVIKVLVATSVAARGLDVKNLILVVNYDCPNHYEDYVHRVGRTGRAGRKGYAYTFVLPEHQEKMAGEICRAFETAGCKPPADLKAMFERFKSEMAAEGKEVKLGGKGFEGSGYKYDEGEAEADANKKRMTRLVHGMEAGGDDDDDLEEQLSSMIKTKRRVVHGKPQSEKPSSSSGNAKNDREAGKRADQAKLKAEELSTRLKGASQVVQPVEKTAAQLTAEAVLRGAEVAPAQMSAAMLAKEKANRLNEKLNYLGGEAAPTQQQEEAWEYFEEEWDINDFPQQVRYKICSRESVGHVAELAEVGISVRGVHVPP---GKEPKNGERRLHLLLEARSERNLKAAKEEIIRIMKEAFRQ 954
[Close]
BLAST of Pre-mRNA-processing ATP-dependent RNA helicase PRP5 vs. Ensembl Celegans
Match: F53H1.1 (pep chromosome:WBcel235:IV:1297400:1309644:-1 gene:WBGene00018776.1 transcript:F53H1.1b.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:F53H1.1)

HSP 1 Score: 521.931 bits (1343), Expect = 1.020e-171
Identity = 250/509 (49.12%), Postives = 350/509 (68.76%), Query Frame = 2 
Query:  749 IEDTDEYHQTVEPETLESITQALFEEKKQKLPDVNHDKVYYRKYDFNLYKEVPEISKMTTKEVKELRRSM-AIVVKGKECPKPITKWSHAIVSMKILNALKYNKMNEPTPIQSQTIPAIMSGKDVIGIAKTGSGKTLSYLLPLIRHIHNQPNVTVGEGPIAIVLCPTRELSIQIHQEIEKITYALRDVNCGCIYGGADTAQQISRLKRGVEIVVGTPGRIIDIMATNGGRNLSLSRCTFIVLDEADRMFDMGFEPQVMAIISRIRPDRQTVMFSATFPRRIEAVAKKIMKEPIEVRVDGGNKVCTDVVQHVYLLDENDKFLKLVELLSEFKYRGKSLVFVETQETAQILSSNLTHQGF-EVSMIHGGLTQEKREEGMFNFKSGTVPILIATSIAARGLDVNDLMMVVNYDCPNHYEDYVHRCGRTGRAGNKGYSYTFVTSD-QEVMIGNLIKALKENGQEIPGELTEAYARYTERMVLEGKTIK-APSGFRGHGYKFDAAEAMKEKGKK 2263
            +E+ D     ++   +E+   +L   K + L   +H KVYYRK+  N Y E  EI +MT  EVK  R  + +I VKG +CPKPI  W+   V++K++N LK  + ++PT IQ+Q IP+IMSG+DVIGIAKTGSGKTL++LLP+ RHI +QP +  G+GPIA++L PTREL++Q ++E  K    L  +   C YGG   ++QI+ LKRG EIVV TPGR+ID++A N G+  +L R T++VLDEADRMFD GFEPQ+M +++ IRPD+QTV+FSATFPR +EA+A+K++ +P+E+ V G + VC+D+ Q+  +  E+ KFLKL+ELL  +   G S+VFV+ QE A  +   L   G+  V+ +HGG+ Q  R+  + +FK+G + +L+ATS+AARGLDV +L++VVNYDCPNHYEDYVHR GRTGRAG KGY+YTFV  + QE M G + +A +  G + P +L   + R+   M  EGK +K    GF G GYK+D  EA  +  KK
Sbjct:  221 LENEDNMDMVIDDFDIETAAASLCH-KGRMLAQTDHSKVYYRKFKKNFYIETEEIRRMTKAEVKAYREELDSITVKGIDCPKPIKTWAQCGVNLKMMNVLKKFEYSKPTSIQAQAIPSIMSGRDVIGIAKTGSGKTLAFLLPMFRHILDQPELEEGDGPIAVILAPTRELAMQTYKEANKFAKPL-GLKVACTYGGVGISEQIADLKRGAEIVVCTPGRMIDVLAANSGKVTNLRRVTYLVLDEADRMFDKGFEPQIMKVVNNIRPDKQTVLFSATFPRHMEALARKVLDKPVEILVGGKSVVCSDITQNAVICAEHQKFLKLLELLGMYYEEGSSIVFVDKQEKADDIVDQLMRTGYNSVAPLHGGIDQHDRDSSIADFKTGVIKVLVATSVAARGLDVKNLILVVNYDCPNHYEDYVHRVGRTGRAGRKGYAYTFVLPEHQEKMAGEICRAFETAGCKPPADLKAMFERFKSEMAAEGKEVKLGGKGFEGSGYKYDEGEAEADANKK 727
[Close]
BLAST of Pre-mRNA-processing ATP-dependent RNA helicase PRP5 vs. Ensembl Celegans
Match: F53H1.1 (pep chromosome:WBcel235:IV:1297283:1309644:-1 gene:WBGene00018776.1 transcript:F53H1.1c.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:F53H1.1)

HSP 1 Score: 387.111 bits (993), Expect = 1.978e-119
Identity = 213/552 (38.59%), Postives = 320/552 (57.97%), Query Frame = 2 
Query: 1307 VNCGCIYGGADTAQQISRLKRGVEIVVGTPGRIIDIMATNGGRNLSLSRCTFIVLDEADRMFDMGFEPQVMAIISRIRPDRQTVMFSATFPRRIEAVAKKIMKEPIEVRVDGGNKVCTDVVQHVYLLDENDKFLKLVELLSEFKYRGKSLVFVETQETAQILSSNLTHQGF-EVSMIHGGLTQEKREEGMFNFKSGTVPILIATSIAARGLDVNDLMMVVNYDCPNHYEDYVHRCGRTGRAGNKGYSYTFVTSD-QEVMIGNLIKALKENGQEIPGELTEAYARYTERMVLEGKTIK-APSGFRGHGYKFDAAEAMKEKGKKLQELFKYCPEEITEEDEAVLEEMQLTSQRTSHQLNANPLV--PQIPSYEAQNH---AKAAHQMAMK---LNMKLDSTGSVVEP--------------------------------------------SGDIAPSSRE---------EIPINNLPANIRYLLTTRDLRTNLSENFDVALTVKGVFMAPKDIKKLEQIGEKPLHLVLESDSPINIRSARNEICRVVKEAMKK 2770
            +   C YGG   ++QI+ LKRG EIVV TPGR+ID++A N G+  +L R T++VLDEADRMFD GFEPQ+M +++ IRPD+QTV+FSATFPR +EA+A+K++ +P+E+ V G + VC+D+ Q+  +  E+ KFLKL+ELL  +   G S+VFV+ QE A  +   L   G+  V+ +HGG+ Q  R+  + +FK+G + +L+ATS+AARGLDV +L++VVNYDCPNHYEDYVHR GRTGRAG KGY+YTFV  + QE M G + +A +  G + P +L   + R+   M  EGK +K    GF G GYK+D  EA  +  KK      +  E   ++D+ + E++    +     ++  P    P   S  A+N     K A Q  +K   L+ +L     VV+P                                             G+ AP+ ++         E  IN+ P  +RY + +R+   +++E  +V ++V+GV + P    K  + GE+ LHL+LE+ S  N+++A+ EI R++KEA ++
Sbjct:  269 IEVACTYGGVGISEQIADLKRGAEIVVCTPGRMIDVLAANSGKVTNLRRVTYLVLDEADRMFDKGFEPQIMKVVNNIRPDKQTVLFSATFPRHMEALARKVLDKPVEILVGGKSVVCSDITQNAVICAEHQKFLKLLELLGMYYEEGSSIVFVDKQEKADDIVDQLMRTGYNSVAPLHGGIDQHDRDSSIADFKTGVIKVLVATSVAARGLDVKNLILVVNYDCPNHYEDYVHRVGRTGRAGRKGYAYTFVLPEHQEKMAGEICRAFETAGCKPPADLKAMFERFKSEMAAEGKEVKLGGKGFEGSGYKYDEGEAEADANKKRMTRLVHGMEAGGDDDDDLEEQLSSMIKTKRRVVHGKPQSEKPSSSSGNAKNDREAGKRADQAKLKAEELSTRLKGASQVVQPVEKTAAQLTAEAVLRGAEVAPAQMSAAMLAKEKANRLNEKLNYLGGEAAPTQQQEEAWEYFEEEWDINDFPQQVRYKICSRESVGHVAELAEVGISVRGVHVPP---GKEPKNGERRLHLLLEARSERNLKAAKEEIIRIMKEAFRQ 817
[Close]
BLAST of Pre-mRNA-processing ATP-dependent RNA helicase PRP5 vs. Ensembl Celegans
Match: F53H1.1 (pep chromosome:WBcel235:IV:1297400:1309644:-1 gene:WBGene00018776.1 transcript:F53H1.1d.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:F53H1.1)

HSP 1 Score: 352.058 bits (902), Expect = 7.529e-109
Identity = 163/322 (50.62%), Postives = 226/322 (70.19%), Query Frame = 2 
Query: 1307 VNCGCIYGGADTAQQISRLKRGVEIVVGTPGRIIDIMATNGGRNLSLSRCTFIVLDEADRMFDMGFEPQVMAIISRIRPDRQTVMFSATFPRRIEAVAKKIMKEPIEVRVDGGNKVCTDVVQHVYLLDENDKFLKLVELLSEFKYRGKSLVFVETQETAQILSSNLTHQGF-EVSMIHGGLTQEKREEGMFNFKSGTVPILIATSIAARGLDVNDLMMVVNYDCPNHYEDYVHRCGRTGRAGNKGYSYTFVTSD-QEVMIGNLIKALKENGQEIPGELTEAYARYTERMVLEGKTIK-APSGFRGHGYKFDAAEAMKEKGKK 2263
            +   C YGG   ++QI+ LKRG EIVV TPGR+ID++A N G+  +L R T++VLDEADRMFD GFEPQ+M +++ IRPD+QTV+FSATFPR +EA+A+K++ +P+E+ V G + VC+D+ Q+  +  E+ KFLKL+ELL  +   G S+VFV+ QE A  +   L   G+  V+ +HGG+ Q  R+  + +FK+G + +L+ATS+AARGLDV +L++VVNYDCPNHYEDYVHR GRTGRAG KGY+YTFV  + QE M G + +A +  G + P +L   + R+   M  EGK +K    GF G GYK+D  EA  +  KK
Sbjct:  269 IEVACTYGGVGISEQIADLKRGAEIVVCTPGRMIDVLAANSGKVTNLRRVTYLVLDEADRMFDKGFEPQIMKVVNNIRPDKQTVLFSATFPRHMEALARKVLDKPVEILVGGKSVVCSDITQNAVICAEHQKFLKLLELLGMYYEEGSSIVFVDKQEKADDIVDQLMRTGYNSVAPLHGGIDQHDRDSSIADFKTGVIKVLVATSVAARGLDVKNLILVVNYDCPNHYEDYVHRVGRTGRAGRKGYAYTFVLPEHQEKMAGEICRAFETAGCKPPADLKAMFERFKSEMAAEGKEVKLGGKGFEGSGYKYDEGEAEADANKK 590
[Close]
BLAST of Pre-mRNA-processing ATP-dependent RNA helicase PRP5 vs. Ensembl Celegans
Match: C46F11.4 (pep chromosome:WBcel235:III:3657716:3664494:-1 gene:WBGene00008119.1 transcript:C46F11.4.2 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:C46F11.4)

HSP 1 Score: 355.91 bits (912), Expect = 4.998e-108
Identity = 177/439 (40.32%), Postives = 282/439 (64.24%), Query Frame = 2 
Query:  839 LPDVNHDKVYYRKYDFNLYKEVPEISKMTTKEVKELRRSMAIVVKGKECPKPITKWSHAIVSMKILNALKYNKMNEPTPIQSQTIPAIMSGKDVIGIAKTGSGKTLSYLLPLIRHIHNQPNVTVGEGPIAIVLCPTRELSIQIHQEIEKITYALRDVNCGCIYGGADTAQQISRLKR-GVEIVVGTPGRIIDIM---ATNGGRNLSLSRCTFIVLDEADRMFDMGFEPQVMAIISRIRPDRQTVMFSATFPRRIEAVAKKIMKEPIEVRVDGGNKVCTDVVQHVYLLDEND-KFLKLVELLSEFKYRGKSLVFVETQETAQILSSNLTHQGFEVSMIHGGLTQEKREEGMFNFKSGTVPILIATSIAARGLDVNDLMMVVNYDCPNHYEDYVHRCGRTGRAGNKGYSYTFVTSDQEVMIGNLIKALKENGQEIPGELTE 2140
            LPD++H ++ Y+K++ N Y+E  +I ++   +V  L+ +M + V G + P+P+  ++H      ++ A++ ++  +PTPIQ+  IP+ +SG+DV+GIAKTGSGKT +YL P I HI +QP++  GEGP+A+++ PTREL+IQ+ QE +K    + ++N  C YGG    +Q + L+  G E+VV TPGRIID++   ATN        R TF+V DEADRMFDMGFE QV +I   +RPDRQ +MFSATF +++E +A+  + +P+ +      +   D+ Q V+++   D K   L+  L EF   GK L+FV  +  ++ ++  L  + F++ ++HG + Q +R E +  F+  +  IL+AT +AARGLD++++  V+N+D     + +VHR GRTGRAG+KG +YT VT     M+G+L+K L+   QE+P  L +
Sbjct:  212 LPDIDHSQIQYQKFNKNFYEEHEDIKRLHYMDVIRLQNTMNLRVGGLKPPRPVCSFAHFSFDKLLMEAIRKSEYEQPTPIQAMAIPSALSGRDVLGIAKTGSGKTAAYLWPAIVHIMDQPDLKAGEGPVAVIVVPTRELAIQVFQEAKKFC-KVYNINPICAYGGGSKWEQSNELQNEGAEMVVCTPGRIIDLVKMGATN------FLRTTFLVFDEADRMFDMGFEAQVKSISDHVRPDRQCLMFSATFKQKVERLARDALVDPVRIVQGEVGEANADIEQKVFVMQNQDVKLHWLIRNLVEFASLGKVLIFVTKKLDSEDVAKKLKMKDFDIVLLHGDMLQAERNENLLKFRKKS-QILVATDVAARGLDISEIRTVINFDMARDIDTHVHRIGRTGRAGHKGTAYTLVTEKDIEMVGHLVKNLESVSQEVPKPLMD 642
[Close]
BLAST of Pre-mRNA-processing ATP-dependent RNA helicase PRP5 vs. Ensembl Fly
Match: CG6227 (gene:FBgn0030631 transcript:FBtr0074011)

HSP 1 Score: 510.375 bits (1313), Expect = 9.397e-162
Identity = 248/488 (50.82%), Postives = 340/488 (69.67%), Query Frame = 2 
Query:  728 GEFTDDHIEDTDEYHQTVEPETLESITQALFEEKKQKLPDVNHDKVYYRKYDFNLYKEVPEISKMTTKEVKELRRSM-AIVVKGKECPKPITKWSHAIVSMKILNALKYNKMNEPTPIQSQTIPAIMSGKDVIGIAKTGSGKTLSYLLPLIRHIHNQPNVTVGEGPIAIVLCPTRELSIQIHQEIEKITYALRDVNCGCIYGGADTAQQISRLKRGVEIVVGTPGRIIDIMATNGGRNLSLSRCTFIVLDEADRMFDMGFEPQVMAIISRIRPDRQTVMFSATFPRRIEAVAKKIMKEPIEVRVDGGNKVCTDVVQHVYLLDENDKFLKLVELLSEFKYRGKSLVFVETQETAQILSSNLTHQGFEVSMIHGGLTQEKREEGMFNFKSGTVPILIATSIAARGLDVNDLMMVVNYDCPNHYEDYVHRCGRTGRAGNKGYSYTFVTSDQEVMIGNLIKALKENGQEIPGELTEAYARYTERMVLEGKTI 2188
            GE  + ++ D+ EY    E E +      L  + +++L  ++H  V Y  +  N Y EVPE+++MT  +V++ R  +  I VKGK CPKPI  W+   VS K +  L+     +PTPIQ Q IPAIMSG+D+IGIAKTGSGKTL+++LP+ RHI +QP++  G+G IAI++ PTREL +QI ++I K + +L  +   C+YGG   ++QI+ LKRG EI+V TPGR+ID++A N GR  +L R T++VLDEADRMFDMGFEPQVM II  +RPDRQTVMFSATFPR++EA+A++I+K+PIEV V G + VC +V QHV +L+++ KF KL+ELL  ++  G  +VFV+ QE A IL  +L    +    +HGG+ Q  R+  + +FKSG V +LIATS+AARGLDV DL++VVNYD PNHYEDYVHRCGRTGRAG KG +YTF+T +Q    G++I+A+  +G  IP EL   +  Y      EGKT+
Sbjct:  420 GEVIEQNM-DSLEYSSEDELEDIRDTAVNLAMKHRKELAKIDHSSVTYAPFRKNFYVEVPELTRMTAADVEKYRSDLEGIQVKGKGCPKPIKTWAQCGVSKKEMEVLRRLGFEKPTPIQCQAIPAIMSGRDLIGIAKTGSGKTLAFILPMFRHILDQPSMEDGDGAIAIIMAPTRELCMQIGKDIRKFSKSL-GLRPVCVYGGTGISEQIAELKRGAEIIVCTPGRMIDMLAANSGRVTNLRRVTYVVLDEADRMFDMGFEPQVMRIIDNVRPDRQTVMFSATFPRQMEALARRILKKPIEVIVGGRSVVCKEVEQHVVILNDDAKFFKLLELLGIYQEAGSIIVFVDKQENADILLRDLMKASYPCMSLHGGIDQFDRDSTIIDFKSGKVRLLIATSVAARGLDVKDLILVVNYDVPNHYEDYVHRCGRTGRAGKKGSAYTFITPEQSRYAGDIIRAMDLSGTLIPAELQALWTEYKALQEAEGKTV 905

HSP 2 Score: 59.3066 bits (142), Expect = 2.015e-8
Identity = 40/127 (31.50%), Postives = 66/127 (51.97%), Query Frame = 2 
Query: 2426 AHQMAMKLNMKLD--------STGSVVEPSGDIAPSSREEIPINNLPANIRYLLTTRDLRTNLSENFDVALTVKGVFMA----PKDIKKLEQIGEKPLHLVLESDSPINIRSARNEICRVVKEAMKK 2770
            A QMA KLN KL+          G +V  + +      EE+ IN+ P   R+ +T+++    +SE  +  LTV+G ++     P D       GE+ L+L +ES S + ++ A+ EI R++KE + K
Sbjct: 1089 AEQMAAKLNNKLNYQPKEDEEGLGPLVGGTTNPFTKYEEELEINDFPQQARWKVTSKEALAQISEYSEAGLTVRGTYVPQGKNPPD-------GERKLYLAIESCSELAVQKAKREITRLIKEELLK 1208
[Close]
BLAST of Pre-mRNA-processing ATP-dependent RNA helicase PRP5 vs. Ensembl Fly
Match: CG6418 (gene:FBgn0036104 transcript:FBtr0076274)

HSP 1 Score: 357.836 bits (917), Expect = 8.259e-109
Identity = 184/473 (38.90%), Postives = 285/473 (60.25%), Query Frame = 2 
Query:  839 LPDVNHDKVYYRKYDFNLYKEVPEISKMTTKEVKELRRSMAIVVKGKECPKPITKWSHAIVSMKILNALKYNKMNEPTPIQSQTIPAIMSGKDVIGIAKTGSGKTLSYLLPLIRHIHNQPNVTVGEGPIAIVLCPTRELSIQIHQEIEKITYALRDVNCGCIYGGADTAQQISRLKRGVEIVVGTPGRIIDIM---ATNGGRNLSLSRCTFIVLDEADRMFDMGFEPQVMAIISRIRPDRQTVMFSATFPRRIEAVAKKIMKEPIEVRVDGGNKVCTDVVQHVYLLDE-----NDKFLKLVELLSEFKYRGKSLVFVETQETAQILSSNLTHQGFEVSMIHGGLTQEKREEGMFNFKSGTVPILIATSIAARGLDVNDLMMVVNYDCPNHYEDYVHRCGRTGRAGNKGYSYTFVTSDQEVMIGNLIKALKENGQEIPGELTE---AYARYTERMVLEGKTIKAPSGFRGHGYK 2224
            LP + H ++ Y  ++ N Y +  +I+ +  ++V+ELRR++ + V G   PKP+T + H     +++ A++  +  +PTPIQ+Q +P  +SG+D+IGIAKTGSGKT +++ P++ H+ +Q  +  G+GPI ++L PTRELS+QI+ E +K    + ++N  C YGG    +Q   L++G EI+V TPGR+ID++   ATN      L R TF+VLDEADRMF MGFEPQV +I + +RPDRQ +MFSATF +RIE +A+ ++ +P+ +     N+   D+ Q VY+        N     LV+ LSE    G  L+FV  +  A+ +S+NL  + +   ++HG + Q  R + +  FK     IL+AT +AARGLD+  +  VVNYD     E + HR GRTGRAG KG +YT VT   +   G+L++ L+   Q +P +L E     + +      +GK  +  +   G GY+
Sbjct:  216 LPPIYHSEIEYEPFEKNFYTQHDDIAALDDEQVRELRRTLGVKVTGPSPPKPVTSFGHFGFDEQLIKAVRKAEYTQPTPIQAQAVPTALSGRDIIGIAKTGSGKTAAFIWPMLMHVMDQKQLKPGDGPIGLILAPTRELSLQIYNEAKKFG-KVYNLNVVCCYGGGSKWEQSKALEQGAEIIVATPGRMIDMVKMKATN------LRRVTFLVLDEADRMFHMGFEPQVRSICNHVRPDRQCLMFSATFKKRIERLARDVLSDPVRIVQGDLNEANQDITQSVYVFPNPLQKWNWLLCHLVKFLSE----GSVLIFVTKKVDAETVSNNLLIKEYNCLLLHGDMDQADRNKVITQFKRKECDILVATDVAARGLDIPHIRNVVNYDTARDIETHTHRIGRTGRAGEKGNAYTLVTDKDKEFAGHLVRNLEGADQLVPDDLMELAMKSSWFRSSRFKQGKGKRPTNTHTGLGYR 677
[Close]
BLAST of Pre-mRNA-processing ATP-dependent RNA helicase PRP5 vs. Ensembl Fly
Match: CG10077 (gene:FBgn0035720 transcript:FBtr0333083)

HSP 1 Score: 348.591 bits (893), Expect = 3.595e-105
Identity = 179/434 (41.24%), Postives = 270/434 (62.21%), Query Frame = 2 
Query:  839 LPDVNHDKVYYRKYDFNLYKEVPEISKMTTKEVKELRRSMAIVVKGKECPKPITKWSHAIVSMKILNALKYNKMNEPTPIQSQTIPAIMSGKDVIGIAKTGSGKTLSYLLPLIRHIHNQPNVTVGEGPIAIVLCPTRELSIQIHQ---EIEKITYALRDVNCGCIYGGADTAQQISRLKRGVEIVVGTPGRIIDIMATNGGRNLSLSRCTFIVLDEADRMFDMGFEPQVMAIISRIRPDRQTVMFSATFPRRIEAVAKKIMKEPIEVRVDGGNKVCT-DVVQHVYLLDENDKFLKLVELLSEFKYRG--KSLVFVETQETAQILSSNLTHQGFEVSMIHGGLTQEKREEGMFNFKSGTVPILIATSIAARGLDVNDLMMVVNYDCPNHYEDYVHRCGRTGRAGNKGYSYTFVTSDQEVMIGNLIKALKENGQEI 2122
            LP +   +V    +  N YK    +   T  E +    S  I +KG + P P  ++        ++N ++     +PT IQ+Q  P  MSG+D++G+A+TGSGKTL+Y+LP + HI+NQP +  G+GPIA+VL PTREL+ QI Q   E    T+    V   CI+GGA   QQ   L+RGVEIV+ TPGR+ID +        SL RCT++VLDEADRM DMGFEPQ+  I+ +IRPDRQ +M+SAT+P+ +  +A++ +   I+V +   +     +++Q V + DEN+K +KL++LL++       K+++FVET++    ++ N++ QG+    IHG  +Q++R+  + +F++G   IL+AT +AARGLDV+D+  V+NYD P++ EDYVHR GRTGR+ N G +YT  T        +LI+ L+E  Q I
Sbjct:  104 LPKIVWSEVNLTPFRKNFYKPCDSVLARTVGETETFLTSNEITIKGDQVPTPSIEFEEGGFPDYVMNEIRKQGFAKPTAIQAQGWPIAMSGRDLVGVAQTGSGKTLAYVLPAVVHINNQPRLERGDGPIALVLAPTRELAQQIQQVAIEFGSNTH----VRNTCIFGGAPKGQQARDLERGVEIVIATPGRLIDFLERG---TTSLKRCTYLVLDEADRMLDMGFEPQIRKIMQQIRPDRQVLMWSATWPKEVRQLAEEFLNNYIQVNIGSLSLSANHNILQIVDVCDENEKLMKLIKLLTDISAENETKTIIFVETKKRVDEITRNISRQGWRACAIHGDKSQQERDFVLSSFRNGRHSILVATDVAARGLDVDDVKFVINYDYPSNSEDYVHRIGRTGRSNNTGTAYTLFTHSNANKANDLIQVLREANQTI 530
[Close]
BLAST of Pre-mRNA-processing ATP-dependent RNA helicase PRP5 vs. Ensembl Fly
Match: CG10077 (gene:FBgn0035720 transcript:FBtr0076940)

HSP 1 Score: 348.591 bits (893), Expect = 3.595e-105
Identity = 179/434 (41.24%), Postives = 270/434 (62.21%), Query Frame = 2 
Query:  839 LPDVNHDKVYYRKYDFNLYKEVPEISKMTTKEVKELRRSMAIVVKGKECPKPITKWSHAIVSMKILNALKYNKMNEPTPIQSQTIPAIMSGKDVIGIAKTGSGKTLSYLLPLIRHIHNQPNVTVGEGPIAIVLCPTRELSIQIHQ---EIEKITYALRDVNCGCIYGGADTAQQISRLKRGVEIVVGTPGRIIDIMATNGGRNLSLSRCTFIVLDEADRMFDMGFEPQVMAIISRIRPDRQTVMFSATFPRRIEAVAKKIMKEPIEVRVDGGNKVCT-DVVQHVYLLDENDKFLKLVELLSEFKYRG--KSLVFVETQETAQILSSNLTHQGFEVSMIHGGLTQEKREEGMFNFKSGTVPILIATSIAARGLDVNDLMMVVNYDCPNHYEDYVHRCGRTGRAGNKGYSYTFVTSDQEVMIGNLIKALKENGQEI 2122
            LP +   +V    +  N YK    +   T  E +    S  I +KG + P P  ++        ++N ++     +PT IQ+Q  P  MSG+D++G+A+TGSGKTL+Y+LP + HI+NQP +  G+GPIA+VL PTREL+ QI Q   E    T+    V   CI+GGA   QQ   L+RGVEIV+ TPGR+ID +        SL RCT++VLDEADRM DMGFEPQ+  I+ +IRPDRQ +M+SAT+P+ +  +A++ +   I+V +   +     +++Q V + DEN+K +KL++LL++       K+++FVET++    ++ N++ QG+    IHG  +Q++R+  + +F++G   IL+AT +AARGLDV+D+  V+NYD P++ EDYVHR GRTGR+ N G +YT  T        +LI+ L+E  Q I
Sbjct:  104 LPKIVWSEVNLTPFRKNFYKPCDSVLARTVGETETFLTSNEITIKGDQVPTPSIEFEEGGFPDYVMNEIRKQGFAKPTAIQAQGWPIAMSGRDLVGVAQTGSGKTLAYVLPAVVHINNQPRLERGDGPIALVLAPTRELAQQIQQVAIEFGSNTH----VRNTCIFGGAPKGQQARDLERGVEIVIATPGRLIDFLERG---TTSLKRCTYLVLDEADRMLDMGFEPQIRKIMQQIRPDRQVLMWSATWPKEVRQLAEEFLNNYIQVNIGSLSLSANHNILQIVDVCDENEKLMKLIKLLTDISAENETKTIIFVETKKRVDEITRNISRQGWRACAIHGDKSQQERDFVLSSFRNGRHSILVATDVAARGLDVDDVKFVINYDYPSNSEDYVHRIGRTGRSNNTGTAYTLFTHSNANKANDLIQVLREANQTI 530
[Close]
BLAST of Pre-mRNA-processing ATP-dependent RNA helicase PRP5 vs. Ensembl Fly
Match: mahe (gene:FBgn0029979 transcript:FBtr0071132)

HSP 1 Score: 339.347 bits (869), Expect = 1.408e-100
Identity = 179/419 (42.72%), Postives = 257/419 (61.34%), Query Frame = 2 
Query:  887 NLYKEVPEISKMTTKEVKELRRSMAIVVKGKECPKPITKWSHAIVSMKILNALKYNKMNEPTPIQSQTIPAIMSGKDVIGIAKTGSGKTLSYLLPLIRHIHNQPNVTVGEGPIAIVLCPTRELSIQIHQEIEKITYALR-DVNCGCIYGGADTAQQISRLKRGVEIVVGTPGRIIDIMATNGGRNLSLSRCTFIVLDEADRMFDMGFEPQVMAIISRIRPDRQTVMFSATFPRRIEAVAKKIMKEPIEVRVDGGN-KVCTDVVQHVYLLDENDKFLKLVELLSE---FKYRG----KSLVFVETQETAQILSSNLTHQGFEVSMIHGGLTQEKREEGMFNFKSGTVPILIATSIAARGLDVNDLMMVVNYDCPNHYEDYVHRCGRTGRAGNKGYSYTFVTSDQEVMIGNLIKALKENGQ 2116
            + Y   P     + ++V E+RR + I V G E P P+  +  + +   ++  +K     +PT IQSQ  P  +SG+D++GIA+TGSGKTL+Y+LP I HI NQP +  GEGPIA+VL PTREL+ QI   +    +  + ++   CI+GG+    Q   L RGVE+++ TPGR+ID +     RN +L RCT++VLDEADRM DMGFEPQ+  II +IRPDRQ VM+SAT+P+ ++A+A   + + I++ +   N     ++ Q V +  E +K  +LV LL+E    K  G    K +VFVET+   + +   +  +G+  + IHG  TQ +R+  + +F++G   ILIAT +A+RGLDV DL  V+NYD PN  E+YVHR GRTGR    G +YTF T D       LI  L+E GQ
Sbjct:  200 DFYNIHPNTLAKSEQQVAEIRRELEITVSGNELPHPVVSFEESSLPAHVIEEMKRQGFTKPTAIQSQGWPIALSGRDLVGIAQTGSGKTLAYMLPAIVHIGNQPPIIRGEGPIALVLAPTRELAQQIQSVVRDYGHLCKPEIRHTCIFGGSSKVPQARDLDRGVEVIIATPGRLIDFLEN---RNTNLQRCTYLVLDEADRMLDMGFEPQIRKIIEQIRPDRQVVMWSATWPKEVQALAGDFLNDYIQINIGSMNLSANHNIRQIVEICTEIEKPQRLVCLLNEISPIKNSGNNGNKIIVFVETKIKVEDILQIIRAEGYNATSIHGDKTQNERDSVLKDFRNGKSNILIATDVASRGLDVEDLQYVINYDYPNSSENYVHRIGRTGRCQQLGTAYTFFTPDNAKQARELISVLEEAGQ 615
[Close]
BLAST of Pre-mRNA-processing ATP-dependent RNA helicase PRP5 vs. Ensembl Zebrafish
Match: ddx46 (DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Source:NCBI gene;Acc:321948])

HSP 1 Score: 543.888 bits (1400), Expect = 1.414e-176
Identity = 262/521 (50.29%), Postives = 366/521 (70.25%), Query Frame = 2 
Query:  722 KIGEFTDDHIEDTDEYHQTVEPETLESITQALFEEKKQKLPDVNHDKVYYRKYDFNLYKEVPEISKMTTKEVKELRRSM-AIVVKGKECPKPITKWSHAIVSMKILNALKYNKMNEPTPIQSQTIPAIMSGKDVIGIAKTGSGKTLSYLLPLIRHIHNQPNVTVGEGPIAIVLCPTRELSIQIHQEIEKIT--YALRDVNCGCIYGGADTAQQISRLKRGVEIVVGTPGRIIDIMATNGGRNLSLSRCTFIVLDEADRMFDMGFEPQVMAIISRIRPDRQTVMFSATFPRRIEAVAKKIMKEPIEVRVDGGNKVCTDVVQHVYLLDENDKFLKLVELLSEFKYRGKSLVFVETQETAQILSSNLTHQGFEVSMIHGGLTQEKREEGMFNFKSGTVPILIATSIAARGLDVNDLMMVVNYDCPNHYEDYVHRCGRTGRAGNKGYSYTFVTSDQEVMIGNLIKALKENGQEIPGELTEAYARYTERMVLEGKTIKAPSGFRGHGYKFDAAE-AMKEKGKKLQE 2272
            K GE  ++  +D  EY    E   L++       ++++ L  V+H K+ Y  +  N Y EVPE+++M+ +EV E R  +  I VKGK CPKPI  W    +SMK+LNALK +   +PTPIQ+Q IPAIMSG+D+IGIAKTGSGKT+++LLP+ RHI +Q  V   EGP+A+++ PTREL++QI +E +K +   ALR V   C+YGG   ++QI+ LKRG EI+V TPGR+ID++  N GR  +L R T++V+DEADRMFDMGFEPQVM I+  +RPDRQTVMFSATFPR +EA+A++I+ +P+EV+V G + VC+DV QHV +++E  KFLKL+E+L  ++ +G  ++FV+ QE A  L  +L    +    +HGG+ Q  R+  + +FK+G   +L+ATS+AARGLDV  L++VVNY CPNHYEDYVHR GRTGRAGNKGY+YTF+T  Q    G+++KAL+ +G  +P EL + +  + E+   EGK IK+ SGF G G+KFD  E A+  + KKLQ+
Sbjct:  248 KKGELMEND-QDAMEYSSEEEEVDLQTALTGFQTKQRKVLEPVDHQKIQYEPFRKNFYVEVPELARMSPEEVSEYRLELEGISVKGKGCPKPIKTWVQCGISMKVLNALKKHNYEKPTPIQAQAIPAIMSGRDLIGIAKTGSGKTIAFLLPMFRHILDQRPVGEAEGPLAVIMTPTRELALQITKECKKFSKSLALRVV---CVYGGTGISEQIAELKRGAEIIVCTPGRMIDMLGANNGRVTNLRRVTYVVIDEADRMFDMGFEPQVMRIVDNVRPDRQTVMFSATFPRTMEALARRILSKPVEVQVGGRSVVCSDVEQHVIVIEEEKKFLKLLEILGHYQEKGSVIIFVDKQEHADGLLKDLMKASYPCMSLHGGIDQYDRDSIINDFKNGACRLLVATSVAARGLDVKQLILVVNYSCPNHYEDYVHRAGRTGRAGNKGYAYTFITEGQARYSGDILKALELSGSSVPAELEQLWTNFKEQQKAEGKIIKSSSGFSGKGFKFDETEHALANERKKLQK 764

HSP 2 Score: 53.1434 bits (126), Expect = 2.212e-6
Identity = 32/120 (26.67%), Postives = 62/120 (51.67%), Query Frame = 2 
Query: 2426 AHQMAMKLNMKLDST-------GSVVEPSGDIAPSSREEIPINNLPANIRYLLTTRDLRTNLSENFDVALTVKGVFMAPKDIKKLEQIGEKPLHLVLESDSPINIRSARNEICRVVKEAM 2764
            A Q A K+N KL+ T             + +      EE+ IN+ P   R+ +T+++    + E  + A+T++G +  P    K  + GE+ ++L +ES + + ++ A+ EI R++KE +
Sbjct:  884 AEQQAEKINAKLNYTPVEKLEEERQAAEAAETVKRYEEELEINDFPQTARWKVTSKEALQRIGEYSEAAITIRGTYFPPG---KEPKEGERKIYLAIESANELAVQKAKAEITRLIKEEL 1000
[Close]
BLAST of Pre-mRNA-processing ATP-dependent RNA helicase PRP5 vs. Ensembl Zebrafish
Match: ddx5 (DEAD (Asp-Glu-Ala-Asp) box helicase 5 [Source:ZFIN;Acc:ZDB-GENE-030131-925])

HSP 1 Score: 366.311 bits (939), Expect = 2.326e-115
Identity = 185/426 (43.43%), Postives = 274/426 (64.32%), Query Frame = 2 
Query:  875 KYDFNLYKEVPEISKMTTKEVKELRRSMAIVVKGKECPKPITKWSHAIVSMKILNALKYNKMNEPTPIQSQTIPAIMSGKDVIGIAKTGSGKTLSYLLPLIRHIHNQPNVTVGEGPIAIVLCPTRELSIQIHQEIEKITYALRDVNCGCIYGGADTAQQISRLKRGVEIVVGTPGRIIDIMATNGGRNLSLSRCTFIVLDEADRMFDMGFEPQVMAIISRIRPDRQTVMFSATFPRRIEAVAKKIMKEPIEVRVDGGNKVCT--DVVQHVYLLDENDKFLKLVELLSEF--KYRGKSLVFVETQETAQILSSNLTHQGFEVSMIHGGLTQEKREEGMFNFKSGTVPILIATSIAARGLDVNDLMMVVNYDCPNHYEDYVHRCGRTGRAGNKGYSYTFVTSDQEVMIGNLIKALKENGQEIPGELTE 2140
            K++ N Y+E P++++ + +EV+  RRS  I VKG++ PKPI K+  A     +++ +      +PTPIQ+Q  P  +SGKD++GIA+TGSGKTLSYLLP I HI++QP +  G+GPI +VL PTREL+ Q+ Q   +   A R +   CIYGGA    QI  L+RGVEI + TPGR+ID +        +L RCT++VLDEADRM DMGFEPQ+  I+ +IRPDRQT+M+SAT+P+ +  +A+  +KE I++ V G  ++    +++Q V + ++ +K  KL+ LL E   +   K+++FVET+     L+  +   G+    IHG   Q++R+  +  FK G  PILIAT +A+RGLDV D+  V+N+D PN+ EDY+HR GRT R+   G +YTF T +      +L+  L+E  Q I  +L +
Sbjct:   55 KFEKNFYQENPDVARRSAQEVEHYRRSKEITVKGRDGPKPIVKFHEANFPKYVMDVITKQNWTDPTPIQAQGWPVALSGKDMVGIAQTGSGKTLSYLLPAIVHINHQPFLEHGDGPICLVLAPTRELAQQVQQVAAEYGKASR-IKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLEAG---KTNLRRCTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAEDFLKEYIQINV-GALQLSANHNILQIVDVCNDGEKEDKLIRLLEEIMSEKENKTIIFVETKRRCDDLTRRMRRDGWPAMGIHGDKNQQERDWVLNEFKYGKAPILIATDVASRGLDVEDVKFVINFDYPNNSEDYIHRIGRTARSQKTGTAYTFFTPNNMKQAHDLVSVLREANQAINPKLIQ 475
[Close]
BLAST of Pre-mRNA-processing ATP-dependent RNA helicase PRP5 vs. Ensembl Zebrafish
Match: ddx5 (DEAD (Asp-Glu-Ala-Asp) box helicase 5 [Source:ZFIN;Acc:ZDB-GENE-030131-925])

HSP 1 Score: 365.54 bits (937), Expect = 1.343e-113
Identity = 185/426 (43.43%), Postives = 274/426 (64.32%), Query Frame = 2 
Query:  875 KYDFNLYKEVPEISKMTTKEVKELRRSMAIVVKGKECPKPITKWSHAIVSMKILNALKYNKMNEPTPIQSQTIPAIMSGKDVIGIAKTGSGKTLSYLLPLIRHIHNQPNVTVGEGPIAIVLCPTRELSIQIHQEIEKITYALRDVNCGCIYGGADTAQQISRLKRGVEIVVGTPGRIIDIMATNGGRNLSLSRCTFIVLDEADRMFDMGFEPQVMAIISRIRPDRQTVMFSATFPRRIEAVAKKIMKEPIEVRVDGGNKVCT--DVVQHVYLLDENDKFLKLVELLSEF--KYRGKSLVFVETQETAQILSSNLTHQGFEVSMIHGGLTQEKREEGMFNFKSGTVPILIATSIAARGLDVNDLMMVVNYDCPNHYEDYVHRCGRTGRAGNKGYSYTFVTSDQEVMIGNLIKALKENGQEIPGELTE 2140
            K++ N Y+E P++++ + +EV+  RRS  I VKG++ PKPI K+  A     +++ +      +PTPIQ+Q  P  +SGKD++GIA+TGSGKTLSYLLP I HI++QP +  G+GPI +VL PTREL+ Q+ Q   +   A R +   CIYGGA    QI  L+RGVEI + TPGR+ID +        +L RCT++VLDEADRM DMGFEPQ+  I+ +IRPDRQT+M+SAT+P+ +  +A+  +KE I++ V G  ++    +++Q V + ++ +K  KL+ LL E   +   K+++FVET+     L+  +   G+    IHG   Q++R+  +  FK G  PILIAT +A+RGLDV D+  V+N+D PN+ EDY+HR GRT R+   G +YTF T +      +L+  L+E  Q I  +L +
Sbjct:   55 KFEKNFYQENPDVARRSAQEVEHYRRSKEITVKGRDGPKPIVKFHEANFPKYVMDVITKQNWTDPTPIQAQGWPVALSGKDMVGIAQTGSGKTLSYLLPAIVHINHQPFLEHGDGPICLVLAPTRELAQQVQQVAAEYGKASR-IKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLEAG---KTNLRRCTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAEDFLKEYIQINV-GALQLSANHNILQIVDVCNDGEKEDKLIRLLEEIMSEKENKTIIFVETKRRCDDLTRRMRRDGWPAMGIHGDKNQQERDWVLNEFKYGKAPILIATDVASRGLDVEDVKFVINFDYPNNSEDYIHRIGRTARSQKTGTAYTFFTPNNMKQAHDLVSVLREANQAINPKLIQ 475
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BLAST of Pre-mRNA-processing ATP-dependent RNA helicase PRP5 vs. Ensembl Zebrafish
Match: DDX17 (si:dkey-156n14.5 [Source:ZFIN;Acc:ZDB-GENE-030131-18])

HSP 1 Score: 362.844 bits (930), Expect = 7.442e-112
Identity = 182/420 (43.33%), Postives = 269/420 (64.05%), Query Frame = 2 
Query:  875 KYDFNLYKEVPEISKMTTKEVKELRRSMAIVVKGKECPKPITKWSHAIVSMKILNALKYNKMNEPTPIQSQTIPAIMSGKDVIGIAKTGSGKTLSYLLPLIRHIHNQPNVTVGEGPIAIVLCPTRELSIQIHQEIEKITYALRDVNCGCIYGGADTAQQISRLKRGVEIVVGTPGRIIDIMATNGGRNLSLSRCTFIVLDEADRMFDMGFEPQVMAIISRIRPDRQTVMFSATFPRRIEAVAKKIMKEPIEVRVDGGNKVCT--DVVQHVYLLDENDKFLKLVELLSEF--KYRGKSLVFVETQETAQILSSNLTHQGFEVSMIHGGLTQEKREEGMFNFKSGTVPILIATSIAARGLDVNDLMMVVNYDCPNHYEDYVHRCGRTGRAGNKGYSYTFVTSDQEVMIGNLIKALKENGQEI 2122
            K++ N Y E PE+  M+  +V+E RR   I V+G  CPKP+T +  A     +++ L      EPT IQ+Q  P  +SG+D++GIA+TGSGKTL+YLLP I HI++QP +  G+GPI +VL PTREL+ Q+ Q       + R +   C+YGGA    QI  L+RGVEI + TPGR+ID +        +L RCT++VLDEADRM DMGFEPQ+  I+ +IRPDRQT+M+SAT+P+ +  +A+  +++ +++ + G  ++    +++Q V +  EN+K  KL++L+ E   +   K+++FVET++    L+  +   G+    IHG  +Q +R+  +  F+SG  PILIAT +A+RGLDV D+  V+NYD PN  EDYVHR GRT R+ NKG +YTF T        +L++ L+E  Q I
Sbjct:   54 KFEKNFYNENPEVHHMSQYDVEEYRRKREITVRGSGCPKPVTNFHQAQFPQYVMDVLLQQNFKEPTAIQAQGFPLALSGRDMVGIAQTGSGKTLAYLLPAIVHINHQPYLERGDGPICLVLAPTRELAQQVQQVAFDYGKSSR-IKSTCVYGGAPKGPQIRDLERGVEICIATPGRLIDFLEVG---KTNLRRCTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAEDFLQDYVQINI-GALELSANHNILQIVDVCMENEKDNKLIQLMEEIMAEKENKTIIFVETKKRCDELTRRMRRDGWPAMCIHGDKSQPERDWVLTEFRSGKAPILIATDVASRGLDVEDVKFVINYDYPNSSEDYVHRIGRTARSTNKGTAYTFFTPGNLRQARDLVRVLEEARQAI 468
[Close]
BLAST of Pre-mRNA-processing ATP-dependent RNA helicase PRP5 vs. Ensembl Zebrafish
Match: ddx42 (DEAD (Asp-Glu-Ala-Asp) box helicase 42 [Source:ZFIN;Acc:ZDB-GENE-050706-53])

HSP 1 Score: 367.081 bits (941), Expect = 5.109e-111
Identity = 184/435 (42.30%), Postives = 271/435 (62.30%), Query Frame = 2 
Query:  839 LPDVNHDKVYYRKYDFNLYKEVPEISKMTTKEVKELRRSMAIVVKGKECPKPITKWSHAIVSMKILNALKYNKMNEPTPIQSQTIPAIMSGKDVIGIAKTGSGKTLSYLLPLIRHIHNQPNVTVGEGPIAIVLCPTRELSIQIHQEIEKI--TYALRDVNCGCIYGGADTAQQISRLKRGVEIVVGTPGRIIDIMATNGGRNLSLSRCTFIVLDEADRMFDMGFEPQVMAIISRIRPDRQTVMFSATFPRRIEAVAKKIMKEPIEVRVDGGNKVCTDVVQHVYLLDEN-DKFLKLVELLSEFKYRGKSLVFVETQETAQILSSNLTHQGFEVSMIHGGLTQEKREEGMFNFKSGTVPILIATSIAARGLDVNDLMMVVNYDCPNHYEDYVHRCGRTGRAGNKGYSYTFVTSDQEVMIGNLIKALKENGQEIPGEL 2134
            LP ++H ++ Y  ++ N Y E  EIS +T  EV ELRR + + V G   PKP T ++H     ++++ ++ ++  +PTPIQ Q +P  +SG+D IGIAKTGSGKT +++ P++ HI +Q  +  GEGPIA+++CPTREL  QIH E ++    Y LR V    +YGG    +Q   L+ G EIVV TPGR+ID +     +  SL R TF+V DEADRMFDMGFE QV +I S +RPDRQT++FSATF ++IE +A+ I+ +PI V      +   D+ Q V +L    DK+  L   L EF   G  LVFV  +   + L++NL  +G+ + ++HG + Q +R + + +FK   +P+L+AT +AARGLD+  +  VVNYD     + + HR GRTGRAG KG +YT +T+      G+L++ L+   Q +  +L
Sbjct:  202 LPPIDHSEIDYSPFEKNFYNEHEEISSLTGAEVVELRRKLNLKVSGAAPPKPATSFAHFGFDEQLMHQIRKSEYTQPTPIQCQGVPIALSGRDAIGIAKTGSGKTAAFIWPILVHIMDQKELEPGEGPIAVIVCPTRELCQQIHAECKRFGKAYGLRSV---AVYGGGSMWEQAKALQEGAEIVVCTPGRLIDHVKK---KATSLQRVTFLVFDEADRMFDMGFEYQVRSIASHVRPDRQTLLFSATFRKKIEKLARDILVDPIRVVQGDIGEANEDITQIVEVLQSGQDKWGWLTRRLVEFTSAGSVLVFVTKKANCEELATNLIQEGYSLGLLHGDMDQSERNKVIADFKKKNLPVLVATDVAARGLDIPSIRTVVNYDVARDIDTHTHRIGRTGRAGEKGVAYTLLTTKDTSFAGDLVRNLEGANQSVSKDL 630
[Close]
BLAST of Pre-mRNA-processing ATP-dependent RNA helicase PRP5 vs. Ensembl Xenopus
Match: DDX46 (DEAD-box helicase 46 [Source:NCBI gene;Acc:100145307])

HSP 1 Score: 533.872 bits (1374), Expect = 9.067e-174
Identity = 272/521 (52.21%), Postives = 367/521 (70.44%), Query Frame = 2 
Query:  722 KIGEFTDDHIEDTDEYHQTVEPETLESITQALFEEKKQKLPDVNHDKVYYRKYDFNLYKEVPEISKMTTKEVKELRRSM-AIVVKGKECPKPITKWSHAIVSMKILNALKYNKMNEPTPIQSQTIPAIMSGKDVIGIAKTGSGKTLSYLLPLIRHIHNQPNVTVGEGPIAIVLCPTRELSIQIHQEIEKI--TYALRDVNCGCIYGGADTAQQISRLKRGVEIVVGTPGRIIDIMATNGGRNLSLSRCTFIVLDEADRMFDMGFEPQVMAIISRIRPDRQTVMFSATFPRRIEAVAKKIMKEPIEVRVDGGNKVCTDVVQHVYLLDENDKFLKLVELLSEFKYRGKSLVFVETQETAQILSSNLTHQGFEVSMIHGGLTQEKREEGMFNFKSGTVPILIATSIAARGLDVNDLMMVVNYDCPNHYEDYVHRCGRTGRAGNKGYSYTFVTSDQEVMIGNLIKALKENGQEIPGELTEAYARYTERMVLEGKTIKAPSGFRGHGYKFDAAE-AMKEKGKKLQE 2272
            K GE  ++  +D  EY    E   L++       ++++ L  V+H K+ Y  Y  N Y EVPE++KMTT+EV   R  +  I VKGK CPKPI  W    +SMKILN+LK +   +PTPIQ+Q IPAIMSG+D+IGIAKTGSGKT+++LLP+ RHI +Q  +  GEGPIA+++ PTREL++QI +E +K   T  LR V   C+YGG   ++QI+ LKRG EI+V TPGR+ID++A N GR  +L R T++VLDEADRMFDMGFEPQVM II  IRPDRQTVMFSATFPR +EA+A++I+ +PIEV+V G + VC+DV QHV +++E  KFLKL+ELL  ++ +G  ++FV+ QE A  L  +L    +    +HGG+ Q  R+  + +FK+G   +L+ATS+AARGLDV  L++V+NY CPNHYEDYVHR GRTGRAGNKGY++TF+T DQ    G++IKAL+ +G  +P EL + +  + E+   EGK IK  SGF G G+KFD  E A+  + KKLQ+
Sbjct:  161 KKGELMEND-QDAMEYSSEEEEVDLQTALTGFQTKQRKLLEPVDHGKIEYESYRKNFYVEVPELAKMTTEEVNSYRLELEGITVKGKNCPKPIKSWVQCGISMKILNSLKKHAYEKPTPIQAQAIPAIMSGRDLIGIAKTGSGKTIAFLLPMFRHIMDQRPLEEGEGPIAVIMTPTRELALQITKECKKFSKTLGLRVV---CVYGGTGISEQIAELKRGAEIIVCTPGRMIDMLAANNGRVTNLRRVTYVVLDEADRMFDMGFEPQVMRIIDNIRPDRQTVMFSATFPRAMEALARRILSKPIEVQVGGRSVVCSDVEQHVIVIEEEKKFLKLLELLGHYQEKGAVIIFVDKQEHADGLLKDLMRASYPCLSLHGGIDQYDRDSIINDFKNGVCKLLVATSVAARGLDVKQLILVINYACPNHYEDYVHRAGRTGRAGNKGYAFTFITEDQARYAGDIIKALELSGTAVPAELEQLWNEFKEQQKAEGKIIKKTSGFSGKGFKFDETEQALANERKKLQK 677

HSP 2 Score: 58.5362 bits (140), Expect = 5.547e-8
Identity = 37/121 (30.58%), Postives = 67/121 (55.37%), Query Frame = 2 
Query: 2426 AHQMAMKLNMKLD--STGSVVEPSGDIAPSS-----REEIPINNLPANIRYLLTTRDLRTNLSENFDVALTVKGVFMAP-KDIKKLEQIGEKPLHLVLESDSPINIRSARNEICRVVKEAM 2764
            A Q+A K+N KL+      + E   D   +       EE+ IN+ P   R+ +T+++    +SE  + A+T++G +  P KD K+    GE+ ++L +ES S + ++ A+ EI R++KE +
Sbjct:  787 AEQLAEKINAKLNYVPVEKLEEEKQDAGANESFKRYEEELEINDFPQTARWKVTSKEALQRISEYSEAAITIRGTYFPPGKDPKE----GERKIYLAIESASELAVQKAKAEITRLIKEEL 903
[Close]
BLAST of Pre-mRNA-processing ATP-dependent RNA helicase PRP5 vs. Ensembl Xenopus
Match: DDX46 (DEAD-box helicase 46 [Source:NCBI gene;Acc:100145307])

HSP 1 Score: 534.258 bits (1375), Expect = 9.753e-174
Identity = 272/521 (52.21%), Postives = 367/521 (70.44%), Query Frame = 2 
Query:  722 KIGEFTDDHIEDTDEYHQTVEPETLESITQALFEEKKQKLPDVNHDKVYYRKYDFNLYKEVPEISKMTTKEVKELRRSM-AIVVKGKECPKPITKWSHAIVSMKILNALKYNKMNEPTPIQSQTIPAIMSGKDVIGIAKTGSGKTLSYLLPLIRHIHNQPNVTVGEGPIAIVLCPTRELSIQIHQEIEKI--TYALRDVNCGCIYGGADTAQQISRLKRGVEIVVGTPGRIIDIMATNGGRNLSLSRCTFIVLDEADRMFDMGFEPQVMAIISRIRPDRQTVMFSATFPRRIEAVAKKIMKEPIEVRVDGGNKVCTDVVQHVYLLDENDKFLKLVELLSEFKYRGKSLVFVETQETAQILSSNLTHQGFEVSMIHGGLTQEKREEGMFNFKSGTVPILIATSIAARGLDVNDLMMVVNYDCPNHYEDYVHRCGRTGRAGNKGYSYTFVTSDQEVMIGNLIKALKENGQEIPGELTEAYARYTERMVLEGKTIKAPSGFRGHGYKFDAAE-AMKEKGKKLQE 2272
            K GE  ++  +D  EY    E   L++       ++++ L  V+H K+ Y  Y  N Y EVPE++KMTT+EV   R  +  I VKGK CPKPI  W    +SMKILN+LK +   +PTPIQ+Q IPAIMSG+D+IGIAKTGSGKT+++LLP+ RHI +Q  +  GEGPIA+++ PTREL++QI +E +K   T  LR V   C+YGG   ++QI+ LKRG EI+V TPGR+ID++A N GR  +L R T++VLDEADRMFDMGFEPQVM II  IRPDRQTVMFSATFPR +EA+A++I+ +PIEV+V G + VC+DV QHV +++E  KFLKL+ELL  ++ +G  ++FV+ QE A  L  +L    +    +HGG+ Q  R+  + +FK+G   +L+ATS+AARGLDV  L++V+NY CPNHYEDYVHR GRTGRAGNKGY++TF+T DQ    G++IKAL+ +G  +P EL + +  + E+   EGK IK  SGF G G+KFD  E A+  + KKLQ+
Sbjct:  161 KKGELMEND-QDAMEYSSEEEEVDLQTALTGFQTKQRKLLEPVDHGKIEYESYRKNFYVEVPELAKMTTEEVNSYRLELEGITVKGKNCPKPIKSWVQCGISMKILNSLKKHAYEKPTPIQAQAIPAIMSGRDLIGIAKTGSGKTIAFLLPMFRHIMDQRPLEEGEGPIAVIMTPTRELALQITKECKKFSKTLGLRVV---CVYGGTGISEQIAELKRGAEIIVCTPGRMIDMLAANNGRVTNLRRVTYVVLDEADRMFDMGFEPQVMRIIDNIRPDRQTVMFSATFPRAMEALARRILSKPIEVQVGGRSVVCSDVEQHVIVIEEEKKFLKLLELLGHYQEKGAVIIFVDKQEHADGLLKDLMRASYPCLSLHGGIDQYDRDSIINDFKNGVCKLLVATSVAARGLDVKQLILVINYACPNHYEDYVHRAGRTGRAGNKGYAFTFITEDQARYAGDIIKALELSGTAVPAELEQLWNEFKEQQKAEGKIIKKTSGFSGKGFKFDETEQALANERKKLQK 677

HSP 2 Score: 58.9214 bits (141), Expect = 5.222e-8
Identity = 37/121 (30.58%), Postives = 67/121 (55.37%), Query Frame = 2 
Query: 2426 AHQMAMKLNMKLD--STGSVVEPSGDIAPSS-----REEIPINNLPANIRYLLTTRDLRTNLSENFDVALTVKGVFMAP-KDIKKLEQIGEKPLHLVLESDSPINIRSARNEICRVVKEAM 2764
            A Q+A K+N KL+      + E   D   +       EE+ IN+ P   R+ +T+++    +SE  + A+T++G +  P KD K+    GE+ ++L +ES S + ++ A+ EI R++KE +
Sbjct:  797 AEQLAEKINAKLNYVPVEKLEEEKQDAGANESFKRYEEELEINDFPQTARWKVTSKEALQRISEYSEAAITIRGTYFPPGKDPKE----GERKIYLAIESASELAVQKAKAEITRLIKEEL 913
[Close]
BLAST of Pre-mRNA-processing ATP-dependent RNA helicase PRP5 vs. Ensembl Xenopus
Match: DDX46 (DEAD-box helicase 46 [Source:NCBI gene;Acc:100145307])

HSP 1 Score: 502.286 bits (1292), Expect = 6.757e-162
Identity = 301/745 (40.40%), Postives = 436/745 (58.52%), Query Frame = 2 
Query:  722 KIGEFTDDHIEDTDEYHQTVEPETLESITQALFEEKKQKLPDVNHDKVYYRKYDFNLYKEVPEISKMTTKEVKELRRSM-AIVVKGKECPKPITKWSHAIVSMKILNALKYNKMNEPTPIQSQTIPAIMSGKDVIGIAKTGSGKTLSYLLPLIRHIHNQPNVTVGEGPIAIVLCPTRELSIQIHQEIEKI--TYALRDVNCGCIYGGADTAQQISRLKRGVEIVVGTPGRIIDIMATNGGRNLSLSRCTFIVLDEADRMFDMGFEPQVMAIISRIRPDRQTVMFSATFPRRIEAVAKKIMKEPIEVRVDGGNKVCTDVVQHVYLLDENDKFLKLVELLSEFKYRGKSLVFVETQETAQILSSNLTHQGFEVSMIHGGLTQEKREEGMFNFKSGTVPILIATSIAARGLDVNDLMMVVNYDCPNHYEDYVHRCGRTGRAGNKGYSYTFVTSDQEVMIGNLIKALKENGQEIPGELTEAYARYTERMVLEGKTIKAPSGFRGHGYKFDAAE-AMKEKGKKLQELFKYCPEEITEEDEAVLEEMQLTSQRTSHQL----------NANPLVPQIPSYEAQNHAKA------------------------------------------AHQMAMKLNMKLD--STGSVVEPSGDIAPSS-----REEIPINNLPANIRYLLTTRDLRTNLSENFDVALTVKGVFMAP-KDIKKLEQIGEKPLHLVLESDSPINIRSARNEICRVVKEAM 2764
            K GE  ++  +D  EY    E   L++       ++++ L  V+H K+ Y  Y  N Y EVPE++KMTT+EV   R  +  I VKGK CPKPI  W    +SMKILN+LK +   +PTPIQ+Q IPAIMSG+D+IGIAKTGSGKT+++LLP+ RHI +Q  +  GEGPIA+++ PTREL++QI +E +K   T  LR V   C+YGG   ++QI+ LKRG EI+V TPGR+ID++A N G+  +      I+         M        II  IRPDRQTVMFSATFPR +EA+A++I+ +PIEV+V G + VC+DV QHV +++E  KFLKL+ELL  ++ +G  ++FV+ QE A  L  +L    +    +HGG+ Q  R+  + +FK+G   +L+ATS+AARGLDV  L++V+NY CPNHYEDYVHR GRTGRAGNKGY++TF+T DQ    G++IKAL+ +G  +P EL + +  + E+   EGK IK  SGF G G+KFD  E A+  + KKLQ+      ++  +ED A+  + Q+ S   S +           +AN  +P   + E    AK                                           A Q+A K+N KL+      + E   D   +       EE+ IN+ P   R+ +T+++    +SE  + A+T++G +  P KD K+    GE+ ++L +ES S + ++ A+ EI R++KE +
Sbjct:  161 KKGELMEND-QDAMEYSSEEEEVDLQTALTGFQTKQRKLLEPVDHGKIEYESYRKNFYVEVPELAKMTTEEVNSYRLELEGITVKGKNCPKPIKSWVQCGISMKILNSLKKHAYEKPTPIQAQAIPAIMSGRDLIGIAKTGSGKTIAFLLPMFRHIMDQRPLEEGEGPIAVIMTPTRELALQITKECKKFSKTLGLRVV---CVYGGTGISEQIAELKRGAEIIVCTPGRMIDMLAANNGKQRAGFFLFQILELLLLPFTKM-------IIIDNIRPDRQTVMFSATFPRAMEALARRILSKPIEVQVGGRSVVCSDVEQHVIVIEEEKKFLKLLELLGHYQEKGAVIIFVDKQEHADGLLKDLMRASYPCLSLHGGIDQYDRDSIINDFKNGVCKLLVATSVAARGLDVKQLILVINYACPNHYEDYVHRAGRTGRAGNKGYAFTFITEDQARYAGDIIKALELSGTAVPAELEQLWNEFKEQQKAEGKIIKKTSGFSGKGFKFDETEQALANERKKLQKA-ALGLQDSDDEDTALDIDEQIESMFNSKKRVKDMAGPGGSSANATLPTAGNAEKLEIAKRLAKKLSVNKNLGAEAQDVMQQATNAILRGGTILAPTVSAKTIAEQLAEKINAKLNYVPVEKLEEEKQDAGANESFKRYEEELEINDFPQTARWKVTSKEALQRISEYSEAAITIRGTYFPPGKDPKE----GERKIYLAIESASELAVQKAKAEITRLIKEEL 889
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BLAST of Pre-mRNA-processing ATP-dependent RNA helicase PRP5 vs. Ensembl Xenopus
Match: ddx17 (DEAD-box helicase 17 [Source:NCBI gene;Acc:549535])

HSP 1 Score: 370.548 bits (950), Expect = 1.359e-116
Identity = 186/427 (43.56%), Postives = 274/427 (64.17%), Query Frame = 2 
Query:  875 KYDFNLYKEVPEISKMTTKEVKELRRSMAIVVKGKECPKPITKWSHAIVSMKILNALKYNKMNEPTPIQSQTIPAIMSGKDVIGIAKTGSGKTLSYLLPLIRHIHNQPNVTVGEGPIAIVLCPTRELSIQIHQEIEKITYALRDVNCGCIYGGADTAQQISRLKRGVEIVVGTPGRIIDIMATNGGRNLSLSRCTFIVLDEADRMFDMGFEPQVMAIISRIRPDRQTVMFSATFPRRIEAVAKKIMKEPIEVRVDGGN---KVCTDVVQHVYLLDENDKFLKLVELLSEF--KYRGKSLVFVETQETAQILSSNLTHQGFEVSMIHGGLTQEKREEGMFNFKSGTVPILIATSIAARGLDVNDLMMVVNYDCPNHYEDYVHRCGRTGRAGNKGYSYTFVTSDQEVMIGNLIKALKENGQEIPGELTE 2140
            K++ N Y E PE+++MT  +V+ELRR   I ++G  CPKPI  +  A     +L+ L   +  EPTPIQ Q  P  +SG+D++GIA+TGSGKTL+YLLP + HI++QP +  G+GPI +VL PTREL+ Q+ Q  +    + R +   CIYGGA    QI  L+RGVEI + TPGR+ID +        +L RCT++VLDEADRM DMGFEPQ+  I+ +IRPDRQT+M+SAT+P+ +  +A+  +++ +++ +  GN       +++Q V +  E++K  KL++L+ E   +   K+++FVET+     L+  +   G+    IHG  +Q++R+  +  F++G  PILIAT +A+RGLDV D+  V+NYD PN  EDYVHR GRT R+ NKG +YTF T         L+K L+E  Q I  +L +
Sbjct:   32 KFEKNFYTEHPEVARMTQHDVEELRRKKEITIRGVNCPKPIYGFHQANFPQYVLDVLIDQRFKEPTPIQCQGFPLALSGRDMVGIAQTGSGKTLAYLLPAMVHINHQPYLERGDGPICLVLAPTRELAQQVQQVADDYGKSSR-LKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLEAG---KTNLRRCTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAEDFLRDYVQINI--GNLELSANHNILQIVDVCQESEKDHKLIQLMEEIMAEKENKTIIFVETKRRCDDLTRRMRRDGWPAMCIHGDKSQQERDWVLCEFRTGKAPILIATDVASRGLDVEDIKFVINYDYPNSSEDYVHRIGRTARSTNKGTAYTFFTPGNLKQARELVKVLEEANQTINPKLMQ 452
[Close]
BLAST of Pre-mRNA-processing ATP-dependent RNA helicase PRP5 vs. Ensembl Xenopus
Match: ddx17 (DEAD-box helicase 17 [Source:NCBI gene;Acc:549535])

HSP 1 Score: 369.777 bits (948), Expect = 2.275e-116
Identity = 186/427 (43.56%), Postives = 274/427 (64.17%), Query Frame = 2 
Query:  875 KYDFNLYKEVPEISKMTTKEVKELRRSMAIVVKGKECPKPITKWSHAIVSMKILNALKYNKMNEPTPIQSQTIPAIMSGKDVIGIAKTGSGKTLSYLLPLIRHIHNQPNVTVGEGPIAIVLCPTRELSIQIHQEIEKITYALRDVNCGCIYGGADTAQQISRLKRGVEIVVGTPGRIIDIMATNGGRNLSLSRCTFIVLDEADRMFDMGFEPQVMAIISRIRPDRQTVMFSATFPRRIEAVAKKIMKEPIEVRVDGGN---KVCTDVVQHVYLLDENDKFLKLVELLSEF--KYRGKSLVFVETQETAQILSSNLTHQGFEVSMIHGGLTQEKREEGMFNFKSGTVPILIATSIAARGLDVNDLMMVVNYDCPNHYEDYVHRCGRTGRAGNKGYSYTFVTSDQEVMIGNLIKALKENGQEIPGELTE 2140
            K++ N Y E PE+++MT  +V+ELRR   I ++G  CPKPI  +  A     +L+ L   +  EPTPIQ Q  P  +SG+D++GIA+TGSGKTL+YLLP + HI++QP +  G+GPI +VL PTREL+ Q+ Q  +    + R +   CIYGGA    QI  L+RGVEI + TPGR+ID +        +L RCT++VLDEADRM DMGFEPQ+  I+ +IRPDRQT+M+SAT+P+ +  +A+  +++ +++ +  GN       +++Q V +  E++K  KL++L+ E   +   K+++FVET+     L+  +   G+    IHG  +Q++R+  +  F++G  PILIAT +A+RGLDV D+  V+NYD PN  EDYVHR GRT R+ NKG +YTF T         L+K L+E  Q I  +L +
Sbjct:   43 KFEKNFYTEHPEVARMTQHDVEELRRKKEITIRGVNCPKPIYGFHQANFPQYVLDVLIDQRFKEPTPIQCQGFPLALSGRDMVGIAQTGSGKTLAYLLPAMVHINHQPYLERGDGPICLVLAPTRELAQQVQQVADDYGKSSR-LKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLEAG---KTNLRRCTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAEDFLRDYVQINI--GNLELSANHNILQIVDVCQESEKDHKLIQLMEEIMAEKENKTIIFVETKRRCDDLTRRMRRDGWPAMCIHGDKSQQERDWVLCEFRTGKAPILIATDVASRGLDVEDIKFVINYDYPNSSEDYVHRIGRTARSTNKGTAYTFFTPGNLKQARELVKVLEEANQTINPKLMQ 463
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BLAST of Pre-mRNA-processing ATP-dependent RNA helicase PRP5 vs. Ensembl Mouse
Match: Ddx46 (DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Source:MGI Symbol;Acc:MGI:1920895])

HSP 1 Score: 551.592 bits (1420), Expect = 2.266e-179
Identity = 320/801 (39.95%), Postives = 473/801 (59.05%), Query Frame = 2 
Query:  650 DTDVDSIDAYMSTLIKTVKDPSI----------------------------------AKIGEFTDDHIEDTDEYHQTVEPETLESITQALFEEKKQKLPDVNHDKVYYRKYDFNLYKEVPEISKMTTKEVKELRRSM-AIVVKGKECPKPITKWSHAIVSMKILNALKYNKMNEPTPIQSQTIPAIMSGKDVIGIAKTGSGKTLSYLLPLIRHIHNQPNVTVGEGPIAIVLCPTRELSIQIHQEIEKI--TYALRDVNCGCIYGGADTAQQISRLKRGVEIVVGTPGRIIDIMATNGGRNLSLSRCTFIVLDEADRMFDMGFEPQVMAIISRIRPDRQTVMFSATFPRRIEAVAKKIMKEPIEVRVDGGNKVCTDVVQHVYLLDENDKFLKLVELLSEFKYRGKSLVFVETQETAQILSSNLTHQGFEVSMIHGGLTQEKREEGMFNFKSGTVPILIATSIAARGLDVNDLMMVVNYDCPNHYEDYVHRCGRTGRAGNKGYSYTFVTSDQEVMIGNLIKALKENGQEIPGELTEAYARYTERMVLEGKTIKAPSGFRGHGYKFDAAE-AMKEKGKKLQELFKYCPEEITEEDEAVLEEMQLTSQRTSHQL---NANPLVPQIPSYEAQNHAKA--AHQMAMKLNMKLD------------STGSVVEPSGDIAPS-----------------------------------------SREEIPINNLPANIRYLLTTRDLRTNLSENFDVALTVKGVFMAPKDIKKLEQIGEKPLHLVLESDSPINIRSARNEICRVVKEAM 2764
            D ++D +DAYM  + + VK  ++                                   K GE  ++  +D  EY    E   L++       ++++ L  V+H K+ Y  +  N Y EVPE++KM+ +EV   R  M  I VKGK CPKPI  W    +SMKILN+LK +   +PTPIQ+Q IPAIMSG+D+IGIAKTGSGKT+++LLP+ RHI +Q ++  GEGPIA+++ PTREL++QI +E +K   T  LR V   C+YGG   ++QI+ LKRG EI+V TPGR+ID++A N GR  +L R T++VLDEADRMFDMGFEPQVM I+  +RPDRQTVMFSATFPR +EA+A++I+ +PIEV+V G + VC+DV Q V +++E  KFLKL+ELL  ++  G  ++FV+ QE A  L  +L    +    +HGG+ Q  R+  + +FK+GT  +L+ATS+AARGLDV  L++VVNY CPNHYEDYVHR GRTGRAGNKGY+YTF+T DQ    G++IKAL+ +G  +P +L + ++ + ++   EGK IK  SGF G G+KFD  E A+  + KKLQ+      ++  +ED AV  + Q+ S   S +     A P    +P+  A N  K   A ++A+++N + +            +T +++     +AP+                                           EE+ IN+ P   R+ +T+++    +SE  + A+T++G +  P    K  + GE+ ++L +ES + + ++ A+ EI R++KE +
Sbjct:  222 DEELDPLDAYMEEVKEEVKKFNMRSVKGGAGNEKKSGPTVTKVVTVVTTKKAVVDADKKKGELMEND-QDAMEYSSEEEEVDLQTALTGYQTKQRKLLEPVDHGKIEYEPFRKNFYVEVPELAKMSQEEVNVFRLEMEGITVKGKGCPKPIKSWVQCGISMKILNSLKKHGYEKPTPIQTQAIPAIMSGRDLIGIAKTGSGKTIAFLLPMFRHIMDQRSLEEGEGPIAVIMTPTRELALQITKECKKFSKTLGLRVV---CVYGGTGISEQIAELKRGAEIIVCTPGRMIDMLAANSGRVTNLRRVTYVVLDEADRMFDMGFEPQVMRIVDNVRPDRQTVMFSATFPRAMEALARRILSKPIEVQVGGRSVVCSDVEQQVIVIEEEKKFLKLLELLGHYQESGSVIIFVDKQEHADGLLKDLMRASYPCMSLHGGIDQYDRDSIINDFKNGTCKLLVATSVAARGLDVKHLILVVNYSCPNHYEDYVHRAGRTGRAGNKGYAYTFITEDQARYAGDIIKALELSGTAVPPDLEKLWSDFKDQQKAEGKIIKKSSGFSGKGFKFDETEQALANERKKLQKA-ALGLQDSDDEDAAVDIDEQIESMFNSKKRVKDMAAPGTSSVPAPTAGNAEKLEIAKRLALRINAQKNLGIESQVDVMQQATNAILRGGTILAPTVSAKTIAEQLAEKINAKLNYVPLEKQEEERQEGGQSESFKRYEEELEINDFPQTARWKVTSKEALQRISEYSEAAITIRGTYFPP---GKEPKEGERKIYLAIESANELAVQKAKAEITRLIKEEL 1014
[Close]
BLAST of Pre-mRNA-processing ATP-dependent RNA helicase PRP5 vs. Ensembl Mouse
Match: Ddx46 (DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Source:MGI Symbol;Acc:MGI:1920895])

HSP 1 Score: 551.592 bits (1420), Expect = 2.266e-179
Identity = 320/801 (39.95%), Postives = 473/801 (59.05%), Query Frame = 2 
Query:  650 DTDVDSIDAYMSTLIKTVKDPSI----------------------------------AKIGEFTDDHIEDTDEYHQTVEPETLESITQALFEEKKQKLPDVNHDKVYYRKYDFNLYKEVPEISKMTTKEVKELRRSM-AIVVKGKECPKPITKWSHAIVSMKILNALKYNKMNEPTPIQSQTIPAIMSGKDVIGIAKTGSGKTLSYLLPLIRHIHNQPNVTVGEGPIAIVLCPTRELSIQIHQEIEKI--TYALRDVNCGCIYGGADTAQQISRLKRGVEIVVGTPGRIIDIMATNGGRNLSLSRCTFIVLDEADRMFDMGFEPQVMAIISRIRPDRQTVMFSATFPRRIEAVAKKIMKEPIEVRVDGGNKVCTDVVQHVYLLDENDKFLKLVELLSEFKYRGKSLVFVETQETAQILSSNLTHQGFEVSMIHGGLTQEKREEGMFNFKSGTVPILIATSIAARGLDVNDLMMVVNYDCPNHYEDYVHRCGRTGRAGNKGYSYTFVTSDQEVMIGNLIKALKENGQEIPGELTEAYARYTERMVLEGKTIKAPSGFRGHGYKFDAAE-AMKEKGKKLQELFKYCPEEITEEDEAVLEEMQLTSQRTSHQL---NANPLVPQIPSYEAQNHAKA--AHQMAMKLNMKLD------------STGSVVEPSGDIAPS-----------------------------------------SREEIPINNLPANIRYLLTTRDLRTNLSENFDVALTVKGVFMAPKDIKKLEQIGEKPLHLVLESDSPINIRSARNEICRVVKEAM 2764
            D ++D +DAYM  + + VK  ++                                   K GE  ++  +D  EY    E   L++       ++++ L  V+H K+ Y  +  N Y EVPE++KM+ +EV   R  M  I VKGK CPKPI  W    +SMKILN+LK +   +PTPIQ+Q IPAIMSG+D+IGIAKTGSGKT+++LLP+ RHI +Q ++  GEGPIA+++ PTREL++QI +E +K   T  LR V   C+YGG   ++QI+ LKRG EI+V TPGR+ID++A N GR  +L R T++VLDEADRMFDMGFEPQVM I+  +RPDRQTVMFSATFPR +EA+A++I+ +PIEV+V G + VC+DV Q V +++E  KFLKL+ELL  ++  G  ++FV+ QE A  L  +L    +    +HGG+ Q  R+  + +FK+GT  +L+ATS+AARGLDV  L++VVNY CPNHYEDYVHR GRTGRAGNKGY+YTF+T DQ    G++IKAL+ +G  +P +L + ++ + ++   EGK IK  SGF G G+KFD  E A+  + KKLQ+      ++  +ED AV  + Q+ S   S +     A P    +P+  A N  K   A ++A+++N + +            +T +++     +AP+                                           EE+ IN+ P   R+ +T+++    +SE  + A+T++G +  P    K  + GE+ ++L +ES + + ++ A+ EI R++KE +
Sbjct:  222 DEELDPLDAYMEEVKEEVKKFNMRSVKGGAGNEKKSGPTVTKVVTVVTTKKAVVDADKKKGELMEND-QDAMEYSSEEEEVDLQTALTGYQTKQRKLLEPVDHGKIEYEPFRKNFYVEVPELAKMSQEEVNVFRLEMEGITVKGKGCPKPIKSWVQCGISMKILNSLKKHGYEKPTPIQTQAIPAIMSGRDLIGIAKTGSGKTIAFLLPMFRHIMDQRSLEEGEGPIAVIMTPTRELALQITKECKKFSKTLGLRVV---CVYGGTGISEQIAELKRGAEIIVCTPGRMIDMLAANSGRVTNLRRVTYVVLDEADRMFDMGFEPQVMRIVDNVRPDRQTVMFSATFPRAMEALARRILSKPIEVQVGGRSVVCSDVEQQVIVIEEEKKFLKLLELLGHYQESGSVIIFVDKQEHADGLLKDLMRASYPCMSLHGGIDQYDRDSIINDFKNGTCKLLVATSVAARGLDVKHLILVVNYSCPNHYEDYVHRAGRTGRAGNKGYAYTFITEDQARYAGDIIKALELSGTAVPPDLEKLWSDFKDQQKAEGKIIKKSSGFSGKGFKFDETEQALANERKKLQKA-ALGLQDSDDEDAAVDIDEQIESMFNSKKRVKDMAAPGTSSVPAPTAGNAEKLEIAKRLALRINAQKNLGIESQVDVMQQATNAILRGGTILAPTVSAKTIAEQLAEKINAKLNYVPLEKQEEERQEGGQSESFKRYEEELEINDFPQTARWKVTSKEALQRISEYSEAAITIRGTYFPP---GKEPKEGERKIYLAIESANELAVQKAKAEITRLIKEEL 1014
[Close]
BLAST of Pre-mRNA-processing ATP-dependent RNA helicase PRP5 vs. Ensembl Mouse
Match: Ddx46 (DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Source:MGI Symbol;Acc:MGI:1920895])

HSP 1 Score: 503.442 bits (1295), Expect = 5.214e-161
Identity = 305/802 (38.03%), Postives = 459/802 (57.23%), Query Frame = 2 
Query:  650 DTDVDSIDAYMSTLIKTVKDPSIAKI----------------------------------GEFTDDHIEDTDEYHQTVEPETLESITQALFEEKKQKLPDVNHDKVYYRKYDFNLYKEVPEISKMTTKEVKELRRSM-AIVVKGKECPKPITKWSHAIVSMKILNALKYNKMNEPTPIQSQTIPAIMSGKDVIGIAKTGSGKTLSYLLPLIRHIHNQPNVTVGEGPIAIVLCPTRELSIQIHQEIEKI--TYALRDVNCGCIYGGADTAQQISRLKRGVEIVVGTPGRIIDIMATNGGRNLSLSRCTFIVLDEADRMFDMGF-EPQVMAIISRIRPDRQTVMFSATFPRRIEAVAKKIMKEPIEVRVDGGNKVCTDVVQHVYLLDENDKFLKLVELLSEFKYRGKSLVFVETQETAQILSSNLTHQGFEVSMIHGGLTQEKREEGMFNFKSGTVPILIATSIAARGLDVNDLMMVVNYDCPNHYEDYVHRCGRTGRAGNKGYSYTFVTSDQEVMIGNLIKALKENGQEIPGELTEAYARYTERMVLEGKTIKAPSGFRGHGYKFDAAE-AMKEKGKKLQELFKYCPEEITEEDEAVLEEMQLTSQRTSHQL---NANPLVPQIPSYEAQNHAKA--AHQMAMKLNMKLD------------STGSVVEPSGDIAPS-----------------------------------------SREEIPINNLPANIRYLLTTRDLRTNLSENFDVALTVKGVFMAPKDIKKLEQIGEKPLHLVLESDSPINIRSARNEICRVVKEAM 2764
            D ++D +DAYM  + + VK  ++  +                                  GE  ++  +D  EY    E   L++       ++++ L  V+H K+ Y  +  N Y EVPE++KM+ +EV   R  M  I VKGK CPKPI  W    +SMKILN+LK +   +PTPIQ+Q IPAIMSG+D+IGIAKTGSGKT+++LLP+ RHI +Q ++  GEGPIA+++ PTREL++QI +E +K   T  LR V   C+YGG   ++QI+ LKRG EI+V TPGR+ID++A N G++       F  L     + DM F E  VM I+  +RPDRQTVMFSATFPR +EA+A++I+ +PIEV+V G + VC+DV Q V +++E  KFLKL+ELL  ++  G  ++FV+ QE A  L  +L    +    +HGG+ Q  R+  + +FK+GT  +L+ATS+AARGLDV  L++VVNY CPNHYEDYVHR GRTGRAGNKGY+YTF+T DQ    G++IKAL+ +G  +P +L + ++ + ++   EGK IK  SGF G G+KFD  E A+  + KKLQ+      ++  +ED AV  + Q+ S   S +     A P    +P+  A N  K   A ++A+++N + +            +T +++     +AP+                                           EE+ IN+ P   R+ +T+++    +SE  + A+T++G +  P    K  + GE+ ++L +ES + + ++ A+ EI R++KE +
Sbjct:  222 DEELDPLDAYMEEVKEEVKKFNMRSVKGGAGNEKKSGPTVTKVVTVVTTKKAVVDADKKKGELMEND-QDAMEYSSEEEEVDLQTALTGYQTKQRKLLEPVDHGKIEYEPFRKNFYVEVPELAKMSQEEVNVFRLEMEGITVKGKGCPKPIKSWVQCGISMKILNSLKKHGYEKPTPIQTQAIPAIMSGRDLIGIAKTGSGKTIAFLLPMFRHIMDQRSLEEGEGPIAVIMTPTRELALQITKECKKFSKTLGLRVV---CVYGGTGISEQIAELKRGAEIIVCTPGRMIDMLAANSGKSR-----VFYYLFSLLFVLDMIFVEADVMRIVDNVRPDRQTVMFSATFPRAMEALARRILSKPIEVQVGGRSVVCSDVEQQVIVIEEEKKFLKLLELLGHYQESGSVIIFVDKQEHADGLLKDLMRASYPCMSLHGGIDQYDRDSIINDFKNGTCKLLVATSVAARGLDVKHLILVVNYSCPNHYEDYVHRAGRTGRAGNKGYAYTFITEDQARYAGDIIKALELSGTAVPPDLEKLWSDFKDQQKAEGKIIKKSSGFSGKGFKFDETEQALANERKKLQKA-ALGLQDSDDEDAAVDIDEQIESMFNSKKRVKDMAAPGTSSVPAPTAGNAEKLEIAKRLALRINAQKNLGIESQVDVMQQATNAILRGGTILAPTVSAKTIAEQLAEKINAKLNYVPLEKQEEERQEGGQSESFKRYEEELEINDFPQTARWKVTSKEALQRISEYSEAAITIRGTYFPP---GKEPKEGERKIYLAIESANELAVQKAKAEITRLIKEEL 1010
[Close]
BLAST of Pre-mRNA-processing ATP-dependent RNA helicase PRP5 vs. Ensembl Mouse
Match: Ddx17 (DEAD (Asp-Glu-Ala-Asp) box polypeptide 17 [Source:MGI Symbol;Acc:MGI:1914290])

HSP 1 Score: 367.466 bits (942), Expect = 8.683e-114
Identity = 190/428 (44.39%), Postives = 272/428 (63.55%), Query Frame = 2 
Query:  875 KYDFNLYKEVPEISKMTTKEVKELRRSMAIVVKGKE-CPKPITKWSHAIVSMKILNALKYNKMNEPTPIQSQTIPAIMSGKDVIGIAKTGSGKTLSYLLPLIRHIHNQPNVTVGEGPIAIVLCPTRELSIQIHQEIEKITYALRDVNCGCIYGGADTAQQISRLKRGVEIVVGTPGRIIDIMATNGGRNLSLSRCTFIVLDEADRMFDMGFEPQVMAIISRIRPDRQTVMFSATFPRRIEAVAKKIMKEPIEVRVDGGN---KVCTDVVQHVYLLDENDKFLKLVELLSEF--KYRGKSLVFVETQETAQILSSNLTHQGFEVSMIHGGLTQEKREEGMFNFKSGTVPILIATSIAARGLDVNDLMMVVNYDCPNHYEDYVHRCGRTGRAGNKGYSYTFVTSDQEVMIGNLIKALKENGQEIPGELTE 2140
            K++ N Y E PE++++T  EV ELRR   I V+G + CPKP+  + HA     +++ L      EPTPIQ Q  P  +SG+D++GIA+TGSGKTL+YLLP I HI++QP +  G+GPI +VL PTREL+ Q+ Q  +      R +   CIYGGA    QI  L+RGVEI + TPGR+ID + +      +L RCT++VLDEADRM DMGFEPQ+  I+ +IRPDRQT+M+SAT+P+ +  +A+  +++  ++ V  GN       +++Q V +  E++K  KL++L+ E   +   K+++FVET+     L+  +   G+    IHG  +Q +R+  +  F+SG  PILIAT +A+RGLDV D+  V+NYD PN  EDYVHR GRT R+ NKG +YTF T         LIK L+E  Q I  +L +
Sbjct:   50 KFEKNFYVEHPEVARLTPYEVDELRRKKEITVRGGDVCPKPVFAFHHANFPQYVMDVLMDQHFTEPTPIQCQGFPLALSGRDMVGIAQTGSGKTLAYLLPAIVHINHQPYLERGDGPICLVLAPTRELAQQVQQVADDYGKCSR-LKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLESG---KTNLRRCTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAEDFLRDYTQINV--GNLELSANHNILQIVDVCMESEKDHKLIQLMEEIMAEKENKTIIFVETKRRCDDLTRRMRRDGWPAMCIHGDKSQPERDWVLNEFRSGKAPILIATDVASRGLDVEDVKFVINYDYPNSSEDYVHRIGRTARSTNKGTAYTFFTPGNLKQARELIKVLEEANQAINPKLMQ 471
[Close]
BLAST of Pre-mRNA-processing ATP-dependent RNA helicase PRP5 vs. Ensembl Mouse
Match: Ddx17 (DEAD (Asp-Glu-Ala-Asp) box polypeptide 17 [Source:MGI Symbol;Acc:MGI:1914290])

HSP 1 Score: 367.466 bits (942), Expect = 9.177e-114
Identity = 190/428 (44.39%), Postives = 272/428 (63.55%), Query Frame = 2 
Query:  875 KYDFNLYKEVPEISKMTTKEVKELRRSMAIVVKGKE-CPKPITKWSHAIVSMKILNALKYNKMNEPTPIQSQTIPAIMSGKDVIGIAKTGSGKTLSYLLPLIRHIHNQPNVTVGEGPIAIVLCPTRELSIQIHQEIEKITYALRDVNCGCIYGGADTAQQISRLKRGVEIVVGTPGRIIDIMATNGGRNLSLSRCTFIVLDEADRMFDMGFEPQVMAIISRIRPDRQTVMFSATFPRRIEAVAKKIMKEPIEVRVDGGN---KVCTDVVQHVYLLDENDKFLKLVELLSEF--KYRGKSLVFVETQETAQILSSNLTHQGFEVSMIHGGLTQEKREEGMFNFKSGTVPILIATSIAARGLDVNDLMMVVNYDCPNHYEDYVHRCGRTGRAGNKGYSYTFVTSDQEVMIGNLIKALKENGQEIPGELTE 2140
            K++ N Y E PE++++T  EV ELRR   I V+G + CPKP+  + HA     +++ L      EPTPIQ Q  P  +SG+D++GIA+TGSGKTL+YLLP I HI++QP +  G+GPI +VL PTREL+ Q+ Q  +      R +   CIYGGA    QI  L+RGVEI + TPGR+ID + +      +L RCT++VLDEADRM DMGFEPQ+  I+ +IRPDRQT+M+SAT+P+ +  +A+  +++  ++ V  GN       +++Q V +  E++K  KL++L+ E   +   K+++FVET+     L+  +   G+    IHG  +Q +R+  +  F+SG  PILIAT +A+RGLDV D+  V+NYD PN  EDYVHR GRT R+ NKG +YTF T         LIK L+E  Q I  +L +
Sbjct:   50 KFEKNFYVEHPEVARLTPYEVDELRRKKEITVRGGDVCPKPVFAFHHANFPQYVMDVLMDQHFTEPTPIQCQGFPLALSGRDMVGIAQTGSGKTLAYLLPAIVHINHQPYLERGDGPICLVLAPTRELAQQVQQVADDYGKCSR-LKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLESG---KTNLRRCTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAEDFLRDYTQINV--GNLELSANHNILQIVDVCMESEKDHKLIQLMEEIMAEKENKTIIFVETKRRCDDLTRRMRRDGWPAMCIHGDKSQPERDWVLNEFRSGKAPILIATDVASRGLDVEDVKFVINYDYPNSSEDYVHRIGRTARSTNKGTAYTFFTPGNLKQARELIKVLEEANQAINPKLMQ 471
[Close]
BLAST of Pre-mRNA-processing ATP-dependent RNA helicase PRP5 vs. UniProt/SwissProt
Match: sp|Q62780|DDX46_RAT (Probable ATP-dependent RNA helicase DDX46 OS=Rattus norvegicus OX=10116 GN=Ddx46 PE=1 SV=1)

HSP 1 Score: 552.362 bits (1422), Expect = 1.004e-178
Identity = 312/743 (41.99%), Postives = 457/743 (61.51%), Query Frame = 2 
Query:  722 KIGEFTDDHIEDTDEYHQTVEPETLESITQALFEEKKQKLPDVNHDKVYYRKYDFNLYKEVPEISKMTTKEVKELRRSM-AIVVKGKECPKPITKWSHAIVSMKILNALKYNKMNEPTPIQSQTIPAIMSGKDVIGIAKTGSGKTLSYLLPLIRHIHNQPNVTVGEGPIAIVLCPTRELSIQIHQEIEKI--TYALRDVNCGCIYGGADTAQQISRLKRGVEIVVGTPGRIIDIMATNGGRNLSLSRCTFIVLDEADRMFDMGFEPQVMAIISRIRPDRQTVMFSATFPRRIEAVAKKIMKEPIEVRVDGGNKVCTDVVQHVYLLDENDKFLKLVELLSEFKYRGKSLVFVETQETAQILSSNLTHQGFEVSMIHGGLTQEKREEGMFNFKSGTVPILIATSIAARGLDVNDLMMVVNYDCPNHYEDYVHRCGRTGRAGNKGYSYTFVTSDQEVMIGNLIKALKENGQEIPGELTEAYARYTERMVLEGKTIKAPSGFRGHGYKFDAAE-AMKEKGKKLQELFKYCPEEITEEDEAVLEEMQLTSQRTSHQL---NANPLVPQIPSYEAQNHAKA--AHQMAMKLNMKLD------------STGSVVEPSGDIAPS-----------------------------------------SREEIPINNLPANIRYLLTTRDLRTNLSENFDVALTVKGVFMAPKDIKKLEQIGEKPLHLVLESDSPINIRSARNEICRVVKEAM 2764
            K GE  ++  +D  EY    E   L++       ++++ L  V+H K+ Y  +  N Y EVPE++KM+ +EV   R  M  I VKGK CPKPI  W    +SMKILN+LK +   +PTPIQ+Q IPAIMSG+D+IGIAKTGSGKT+++LLP+ RHI +Q ++  GEGPIA+++ PTREL++QI +E +K   T  LR V   C+YGG   ++QI+ LKRG EI+V TPGR+ID++A N GR  +L R T++VLDEADRMFDMGFEPQVM I+  +RPDRQTVMFSATFPR +EA+A++I+ +PIEV+V G + VC+DV Q V +++E  KFLKL+ELL  ++  G  ++FV+ QE A  L  +L    +    +HGG+ Q  R+  + +FK+GT  +L+ATS+AARGLDV  L++VVNY CPNHYEDYVHR GRTGRAGNKGY+YTF+T DQ    G++IKAL+ +G  +P +L + ++ + ++   EGK IK  SGF G G+KFD  E A+  + KKLQ+      ++  +ED AV  + Q+ S   S +     A P     P+  A N  K   A ++A+++N + +            +T +++     +AP+                                           EE+ IN+ P   R+ +T+++    +SE  + A+T++G +  P    K  + GE+ ++L +ES + + ++ A+ EI R++KE +
Sbjct:  280 KKGELMEND-QDAMEYSSEEEEVDLQTALTGYQTKQRKLLEPVDHGKIEYEPFRKNFYVEVPELAKMSQEEVNVFRLEMEGITVKGKGCPKPIKSWVQCGISMKILNSLKKHGYEKPTPIQTQAIPAIMSGRDLIGIAKTGSGKTIAFLLPMFRHIMDQRSLEEGEGPIAVIMTPTRELALQITKECKKFSKTLGLRVV---CVYGGTGISEQIAELKRGAEIIVCTPGRMIDMLAANSGRVTNLRRVTYVVLDEADRMFDMGFEPQVMRIVDNVRPDRQTVMFSATFPRAMEALARRILSKPIEVQVGGRSVVCSDVEQQVIVIEEEKKFLKLLELLGHYQESGSVIIFVDKQEHADGLLKDLMRASYPCMSLHGGIDQYDRDSIINDFKNGTCKLLVATSVAARGLDVKHLILVVNYSCPNHYEDYVHRAGRTGRAGNKGYAYTFITEDQARYAGDIIKALELSGTAVPPDLEKLWSDFKDQQKAEGKIIKKSSGFSGKGFKFDETEQALANERKKLQKA-ALGLQDSDDEDAAVDIDEQIESMFNSKKRVKDMAAPGTSSAPAPTAGNAEKLEIAKRLALRINAQKNLGIESQVDVMQQATNAILRGGPLLAPTVSAKTIAEQLAEKINAKLNYVPLEKQEEERQEGGQSESFKRYEEELEINDFPQTARWKVTSKEALQRISEYSEAAITIRGTYFPP---GKEPKEGERKIYLAIESANELAVQKAKAEITRLIKEEL 1014
[Close]
BLAST of Pre-mRNA-processing ATP-dependent RNA helicase PRP5 vs. UniProt/SwissProt
Match: sp|Q569Z5|DDX46_MOUSE (Probable ATP-dependent RNA helicase DDX46 OS=Mus musculus OX=10090 GN=Ddx46 PE=1 SV=2)

HSP 1 Score: 551.592 bits (1420), Expect = 1.585e-178
Identity = 320/801 (39.95%), Postives = 473/801 (59.05%), Query Frame = 2 
Query:  650 DTDVDSIDAYMSTLIKTVKDPSI----------------------------------AKIGEFTDDHIEDTDEYHQTVEPETLESITQALFEEKKQKLPDVNHDKVYYRKYDFNLYKEVPEISKMTTKEVKELRRSM-AIVVKGKECPKPITKWSHAIVSMKILNALKYNKMNEPTPIQSQTIPAIMSGKDVIGIAKTGSGKTLSYLLPLIRHIHNQPNVTVGEGPIAIVLCPTRELSIQIHQEIEKI--TYALRDVNCGCIYGGADTAQQISRLKRGVEIVVGTPGRIIDIMATNGGRNLSLSRCTFIVLDEADRMFDMGFEPQVMAIISRIRPDRQTVMFSATFPRRIEAVAKKIMKEPIEVRVDGGNKVCTDVVQHVYLLDENDKFLKLVELLSEFKYRGKSLVFVETQETAQILSSNLTHQGFEVSMIHGGLTQEKREEGMFNFKSGTVPILIATSIAARGLDVNDLMMVVNYDCPNHYEDYVHRCGRTGRAGNKGYSYTFVTSDQEVMIGNLIKALKENGQEIPGELTEAYARYTERMVLEGKTIKAPSGFRGHGYKFDAAE-AMKEKGKKLQELFKYCPEEITEEDEAVLEEMQLTSQRTSHQL---NANPLVPQIPSYEAQNHAKA--AHQMAMKLNMKLD------------STGSVVEPSGDIAPS-----------------------------------------SREEIPINNLPANIRYLLTTRDLRTNLSENFDVALTVKGVFMAPKDIKKLEQIGEKPLHLVLESDSPINIRSARNEICRVVKEAM 2764
            D ++D +DAYM  + + VK  ++                                   K GE  ++  +D  EY    E   L++       ++++ L  V+H K+ Y  +  N Y EVPE++KM+ +EV   R  M  I VKGK CPKPI  W    +SMKILN+LK +   +PTPIQ+Q IPAIMSG+D+IGIAKTGSGKT+++LLP+ RHI +Q ++  GEGPIA+++ PTREL++QI +E +K   T  LR V   C+YGG   ++QI+ LKRG EI+V TPGR+ID++A N GR  +L R T++VLDEADRMFDMGFEPQVM I+  +RPDRQTVMFSATFPR +EA+A++I+ +PIEV+V G + VC+DV Q V +++E  KFLKL+ELL  ++  G  ++FV+ QE A  L  +L    +    +HGG+ Q  R+  + +FK+GT  +L+ATS+AARGLDV  L++VVNY CPNHYEDYVHR GRTGRAGNKGY+YTF+T DQ    G++IKAL+ +G  +P +L + ++ + ++   EGK IK  SGF G G+KFD  E A+  + KKLQ+      ++  +ED AV  + Q+ S   S +     A P    +P+  A N  K   A ++A+++N + +            +T +++     +AP+                                           EE+ IN+ P   R+ +T+++    +SE  + A+T++G +  P    K  + GE+ ++L +ES + + ++ A+ EI R++KE +
Sbjct:  222 DEELDPLDAYMEEVKEEVKKFNMRSVKGGAGNEKKSGPTVTKVVTVVTTKKAVVDADKKKGELMEND-QDAMEYSSEEEEVDLQTALTGYQTKQRKLLEPVDHGKIEYEPFRKNFYVEVPELAKMSQEEVNVFRLEMEGITVKGKGCPKPIKSWVQCGISMKILNSLKKHGYEKPTPIQTQAIPAIMSGRDLIGIAKTGSGKTIAFLLPMFRHIMDQRSLEEGEGPIAVIMTPTRELALQITKECKKFSKTLGLRVV---CVYGGTGISEQIAELKRGAEIIVCTPGRMIDMLAANSGRVTNLRRVTYVVLDEADRMFDMGFEPQVMRIVDNVRPDRQTVMFSATFPRAMEALARRILSKPIEVQVGGRSVVCSDVEQQVIVIEEEKKFLKLLELLGHYQESGSVIIFVDKQEHADGLLKDLMRASYPCMSLHGGIDQYDRDSIINDFKNGTCKLLVATSVAARGLDVKHLILVVNYSCPNHYEDYVHRAGRTGRAGNKGYAYTFITEDQARYAGDIIKALELSGTAVPPDLEKLWSDFKDQQKAEGKIIKKSSGFSGKGFKFDETEQALANERKKLQKA-ALGLQDSDDEDAAVDIDEQIESMFNSKKRVKDMAAPGTSSVPAPTAGNAEKLEIAKRLALRINAQKNLGIESQVDVMQQATNAILRGGTILAPTVSAKTIAEQLAEKINAKLNYVPLEKQEEERQEGGQSESFKRYEEELEINDFPQTARWKVTSKEALQRISEYSEAAITIRGTYFPP---GKEPKEGERKIYLAIESANELAVQKAKAEITRLIKEEL 1014
[Close]
BLAST of Pre-mRNA-processing ATP-dependent RNA helicase PRP5 vs. UniProt/SwissProt
Match: sp|Q7L014|DDX46_HUMAN (Probable ATP-dependent RNA helicase DDX46 OS=Homo sapiens OX=9606 GN=DDX46 PE=1 SV=2)

HSP 1 Score: 550.436 bits (1417), Expect = 5.123e-178
Identity = 320/798 (40.10%), Postives = 471/798 (59.02%), Query Frame = 2 
Query:  656 DVDSIDAYMSTLIKTVKD----------------------------------PSIAKIGEFTDDHIEDTDEYHQTVEPETLESITQALFEEKKQKLPDVNHDKVYYRKYDFNLYKEVPEISKMTTKEVKELRRSM-AIVVKGKECPKPITKWSHAIVSMKILNALKYNKMNEPTPIQSQTIPAIMSGKDVIGIAKTGSGKTLSYLLPLIRHIHNQPNVTVGEGPIAIVLCPTRELSIQIHQEIEKI--TYALRDVNCGCIYGGADTAQQISRLKRGVEIVVGTPGRIIDIMATNGGRNLSLSRCTFIVLDEADRMFDMGFEPQVMAIISRIRPDRQTVMFSATFPRRIEAVAKKIMKEPIEVRVDGGNKVCTDVVQHVYLLDENDKFLKLVELLSEFKYRGKSLVFVETQETAQILSSNLTHQGFEVSMIHGGLTQEKREEGMFNFKSGTVPILIATSIAARGLDVNDLMMVVNYDCPNHYEDYVHRCGRTGRAGNKGYSYTFVTSDQEVMIGNLIKALKENGQEIPGELTEAYARYTERMVLEGKTIKAPSGFRGHGYKFDAAE-AMKEKGKKLQELFKYCPEEITEEDEAVLEEMQLTSQRTSHQL---NANPLVPQIPSYEAQNHAKA--AHQMAMKLNMKLD-----------STGSVVEPSGDIAPS-----------------------------------------SREEIPINNLPANIRYLLTTRDLRTNLSENFDVALTVKGVFMAPKDIKKLEQIGEKPLHLVLESDSPINIRSARNEICRVVKEAM 2764
            ++D +DAYM  + + VK                                    S  K GE  ++  +D  EY    E   L++       ++++ L  V+H K+ Y  +  N Y EVPE++KM+ +EV   R  M  I VKGK CPKPI  W    +SMKILN+LK +   +PTPIQ+Q IPAIMSG+D+IGIAKTGSGKT+++LLP+ RHI +Q ++  GEGPIA+++ PTREL++QI +E +K   T  LR V   C+YGG   ++QI+ LKRG EI+V TPGR+ID++A N GR  +L R T++VLDEADRMFDMGFEPQVM I+  +RPDRQTVMFSATFPR +EA+A++I+ +PIEV+V G + VC+DV Q V +++E  KFLKL+ELL  ++  G  ++FV+ QE A  L  +L    +    +HGG+ Q  R+  + +FK+GT  +L+ATS+AARGLDV  L++VVNY CPNHYEDYVHR GRTGRAGNKGY+YTF+T DQ    G++IKAL+ +G  +P +L + ++ + ++   EGK IK  SGF G G+KFD  E A+  + KKLQ+      ++  +ED AV  + Q+ S   S +     A P    +P+  A N  K   A ++A+++N + +           +T +++     +AP+                                           EE+ IN+ P   R+ +T+++    +SE  + A+T++G +  P    K  + GE+ ++L +ES + + ++ A+ EI R++KE +
Sbjct:  224 ELDPLDAYMEEVKEEVKKFNMRSVKGGGGNEKKSGPTVTKVVTVVTTKKAVVDSDKKKGELMEND-QDAMEYSSEEEEVDLQTALTGYQTKQRKLLEPVDHGKIEYEPFRKNFYVEVPELAKMSQEEVNVFRLEMEGITVKGKGCPKPIKSWVQCGISMKILNSLKKHGYEKPTPIQTQAIPAIMSGRDLIGIAKTGSGKTIAFLLPMFRHIMDQRSLEEGEGPIAVIMTPTRELALQITKECKKFSKTLGLRVV---CVYGGTGISEQIAELKRGAEIIVCTPGRMIDMLAANSGRVTNLRRVTYVVLDEADRMFDMGFEPQVMRIVDNVRPDRQTVMFSATFPRAMEALARRILSKPIEVQVGGRSVVCSDVEQQVIVIEEEKKFLKLLELLGHYQESGSVIIFVDKQEHADGLLKDLMRASYPCMSLHGGIDQYDRDSIINDFKNGTCKLLVATSVAARGLDVKHLILVVNYSCPNHYEDYVHRAGRTGRAGNKGYAYTFITEDQARYAGDIIKALELSGTAVPPDLEKLWSDFKDQQKAEGKIIKKSSGFSGKGFKFDETEQALANERKKLQKA-ALGLQDSDDEDAAVDIDEQIESMFNSKKRVKDMAAPGTSSVPAPTAGNAEKLEIAKRLALRINAQKNLGIESQDVMQQATNAILRGGTILAPTVSAKTIAEQLAEKINAKLNYVPLEKQEEERQDGGQNESFKRYEEELEINDFPQTARWKVTSKEALQRISEYSEAAITIRGTYFPP---GKEPKEGERKIYLAIESANELAVQKAKAEITRLIKEEL 1013
[Close]
BLAST of Pre-mRNA-processing ATP-dependent RNA helicase PRP5 vs. UniProt/SwissProt
Match: sp|Q5R6D8|DDX46_PONAB (Probable ATP-dependent RNA helicase DDX46 OS=Pongo abelii OX=9601 GN=DDX46 PE=2 SV=1)

HSP 1 Score: 546.584 bits (1407), Expect = 1.328e-176
Identity = 319/799 (39.92%), Postives = 469/799 (58.70%), Query Frame = 2 
Query:  656 DVDSIDAYMSTLIKTVKD----------------------------------PSIAKIGEFTDDHIEDTDEYHQTVEPETLESITQALFEEKKQKLPDVNHDKVYYRKYDFNLYKEVPEISKMTTKEVKELRRSM-AIVVKGKECPKPITKWSHAIVSMKILNALKYNKMNEPTPIQSQTIPAIMSGKDVIGIAKTGSGKTLSYLLPLIRHIHNQPNVTVGEGPIAIVLCPTRELSIQIHQEIEKI--TYALRDVNCGCIYGGADTAQQISRLKRGVEIVVGTPGRIIDIMATNGGRNLSLSRCTFIVLDEADRMFDMGFEPQVMAIISRIRPDRQTVMFSATFPRRIEAVAKKIMKEPIEVRVDGGNKVCTDVVQHVYLLDENDKFLKLVELLSEFKYRGKSLVFVETQETAQILSSNLTHQGFEVSMIHGGLTQEKREEGMFNFKSGTVPILIATSIAARGLDVNDLMMVVNYDCPNHYEDYVHRCGRTGRAGNKGYSYTFVTSDQEVMIGNLIKALKENGQEIPGELTEAYARYTERMVLEGKTIKAPSGFRGHGYKFDAAE-AMKEKGKKLQELFKYCPEEITEEDEAVLEEMQLTSQRTSHQL---NANPLVPQIPSYEAQNHAKA--AHQMAMKLNMKLD------------STGSVVEPSGDIAPS-----------------------------------------SREEIPINNLPANIRYLLTTRDLRTNLSENFDVALTVKGVFMAPKDIKKLEQIGEKPLHLVLESDSPINIRSARNEICRVVKEAM 2764
            ++D +DAYM  + + VK                                    S  K GE  ++  +D  EY    E   L++       ++++ L  V+H K+ Y  +  N Y EVPE++KM+ +EV   R  M  I VKGK CPKPI  W    +SMKILN+LK +   +PTPIQ+Q IPAIMSG+D+IGIAKTGSGKT+++LLP+ RHI +Q ++  GEGPIA+++ PTREL++QI +E +K   T  LR V   C+YGG   ++QI+ LKRG EI+V TPGR+ID++A N GR  +L R T++VLDEADRMFDMGFEPQVM I+  +RPDRQTVMFSATFPR +EA+ ++I+ +PIEV+V G + VC+DV Q V +++E  KFLKL+ELL  ++  G  ++FV+ QE A  L  +L    +    +HGG+ Q  R+  + +FK+GT  +L+ATS+AARGLDV  L++VVNY CPNHYEDYVHR GRTGRAGNKGY+YTF+T DQ    G++IKAL+ +G  +P +L + ++ + ++   EGK IK  SGF G G+KFD  E A+  + KKLQ+      ++  +ED AV  + Q+ S   S +     A P     P+  A N  K   A ++A+++N + +            +T +++     +AP+                                           EE+ IN+ P   R+ +T+++    +SE  + A+T++G +  P    K  + GE+ ++L +ES + + ++ A+ EI R++KE +
Sbjct:  224 ELDPLDAYMEEVKEEVKKFNMRSVKGGGGNEKKSGPTVTKVVTVVTTKKAVVDSDKKKGELMEND-QDAMEYSSEEEEVDLQTALTGYQTKQRKLLEPVDHGKIEYEPFRKNFYVEVPELAKMSQEEVNVFRLEMEGITVKGKGCPKPIKSWVQCGISMKILNSLKKHGYEKPTPIQTQAIPAIMSGRDLIGIAKTGSGKTIAFLLPMFRHIMDQRSLEEGEGPIAVIMTPTRELALQITKECKKFSKTLGLRVV---CVYGGTGISEQIAELKRGAEIIVCTPGRMIDMLAANSGRVTNLRRVTYVVLDEADRMFDMGFEPQVMRIVDNVRPDRQTVMFSATFPRAMEALVRRILSKPIEVQVGGRSVVCSDVEQQVIVIEEEKKFLKLLELLGHYQESGSVIIFVDKQEHADGLLKDLMRASYPCMSLHGGIDQYDRDSIINDFKNGTCKLLVATSVAARGLDVKHLILVVNYSCPNHYEDYVHRAGRTGRAGNKGYAYTFITEDQARYAGDIIKALELSGTAVPPDLEKLWSDFKDQQKAEGKIIKKSSGFSGKGFKFDETEQALANERKKLQKA-ALGLQDSDDEDAAVDIDEQIESMFNSKKRVKDMAAPGTSSAPAPTAGNAEKLEIAKRLALRINAQKNLGIESQVDVMQQATNAILRGGTILAPTVSAKTIAEQLAEKINAKLNYVPLEKQEEERQDGGQNESFKRYEEELEINDFPQTARWKVTSKEALQRISEYSEAAITIRGTYFPP---GKEPKEGERKIYLAIESANELAVQKAKAEITRLIKEEL 1014
[Close]
BLAST of Pre-mRNA-processing ATP-dependent RNA helicase PRP5 vs. UniProt/SwissProt
Match: sp|Q4TVV3|DDX46_DANRE (Probable ATP-dependent RNA helicase DDX46 OS=Danio rerio OX=7955 GN=ddx46 PE=2 SV=1)

HSP 1 Score: 544.273 bits (1401), Expect = 7.363e-176
Identity = 262/522 (50.19%), Postives = 366/522 (70.11%), Query Frame = 2 
Query:  722 KIGEFTDDHIEDTDEYHQTVEPETLESITQALFEEKKQKLPDVNHDKVYYRKYDFNLYKEVPEISKMTTKEVKELRRSM-AIVVKGKECPKPITKWSHAIVSMKILNALKYNKMNEPTPIQSQTIPAIMSGKDVIGIAKTGSGKTLSYLLPLIRHIHNQPNVTVGEGPIAIVLCPTRELSIQIHQEIEKIT--YALRDVNCGCIYGGADTAQQISRLKRGVEIVVGTPGRIIDIMATNGGRNLSLSRCTFIVLDEADRMFDMGFEPQVMAIISRIRPDRQTVMFSATFPRRIEAVAKKIMKEPIEVRVDGGNKVCTDVVQHVYLLDENDKFLKLVELLSEFKYRGKSLVFVETQETAQILSSNLTHQGFEVSMIHGGLTQEKREEGMFNFKSGTVPILIATSIAARGLDVNDLMMVVNYDCPNHYEDYVHRCGRTGRAGNKGYSYTFVTSDQEVMIGNLIKALKENGQEIPGELTEAYARYTERMVLEGKTIKAPSGFRGHGYKFDAAE-AMKEKGKKLQEL 2275
            K GE  ++  +D  EY    E   L++       ++++ L  V+H K+ Y  +  N Y EVPE+++M+ +EV E R  +  I VKGK CPKPI  W    +SMK+LNALK +   +PTPIQ+Q IPAIMSG+D+IGIAKTGSGKT+++LLP+ RHI +Q  V   EGP+A+++ PTREL++QI +E +K +   ALR V   C+YGG   ++QI+ LKRG EI+V TPGR+ID++  N GR  +L R T++V+DEADRMFDMGFEPQVM I+  +RPDRQTVMFSATFPR +EA+A++I+ +P+EV+V G + VC+DV QHV +++E  KFLKL+E+L  ++ +G  ++FV+ QE A  L  +L    +    +HGG+ Q  R+  + +FK+G   +L+ATS+AARGLDV  L++VVNY CPNHYEDYVHR GRTGRAGNKGY+YTF+T  Q    G+++KAL+ +G  +P EL + +  + E+   EGK IK+ SGF G G+KFD  E A+  + KKLQ+ 
Sbjct:  248 KKGELMEND-QDAMEYSSEEEEVDLQTALTGFQTKQRKVLEPVDHQKIQYEPFRKNFYVEVPELARMSPEEVSEYRLELEGISVKGKGCPKPIKTWVQCGISMKVLNALKKHNYEKPTPIQAQAIPAIMSGRDLIGIAKTGSGKTIAFLLPMFRHILDQRPVGEAEGPLAVIMTPTRELALQITKECKKFSKSLALRVV---CVYGGTGISEQIAELKRGAEIIVCTPGRMIDMLGANNGRVTNLRRVTYVVIDEADRMFDMGFEPQVMRIVDNVRPDRQTVMFSATFPRTMEALARRILSKPVEVQVGGRSVVCSDVEQHVIVIEEEKKFLKLLEILGHYQEKGSVIIFVDKQEHADGLLKDLMKASYPCMSLHGGIDQYDRDSIINDFKNGACRLLVATSVAARGLDVKQLILVVNYSCPNHYEDYVHRAGRTGRAGNKGYAYTFITEGQARYSGDILKALELSGSSVPAELEQLWTNFKEQQKAEGKIIKSSSGFSGKGFKFDETEHALANERKKLQKW 765
[Close]
BLAST of Pre-mRNA-processing ATP-dependent RNA helicase PRP5 vs. TrEMBL
Match: A0A564YRS8 (Uncharacterized protein OS=Hymenolepis diminuta OX=6216 GN=WMSIL1_LOCUS8536 PE=4 SV=1)

HSP 1 Score: 593.964 bits (1530), Expect = 0.000e+0
Identity = 332/784 (42.35%), Postives = 473/784 (60.33%), Query Frame = 2 
Query:  647 VDTDVDSIDAYMSTLIKTVKDPSIAKIGEFTDDHIEDTDEYHQTVEPETLESITQALFE-EKKQKLPDVNHDKVYYRKYDFNLYKEVPEISKMTTKEVKELRRSMAIV-VKGKECPKPITKWSHAIVSMKILNALKYNKMNEPTPIQSQTIPAIMSGKDVIGIAKTGSGKTLSYLLPLIRHIHNQPNVTVGEGPIAIVLCPTRELSIQIHQEIEKI--TYALRDVNCGCIYGGADTAQQISRLKRGVEIVVGTPGRIIDIMATNGGRNLSLSRCTFIVLDEADRMFDMGFEPQVMAIISRIRPDRQTVMFSATFPRRIEAVAKKIMKEPIEVRVDGGNKVCTDVVQHVYLL-DENDKFLKLVELLSEFKYRGKSLVFVETQETAQILSSNLTHQGFEVSMIHGGLTQEKREEGMFNFKSGTVPILIATSIAARGLDVNDLMMVVNYDCPNHYEDYVHRCGRTGRAGNKGYSYTFVTSDQEVMIGNLIKALKENGQEIPGELTEAYARYTERMVLEGKTI--KAPSGFRGHGYKFDAAEAMKEKGKKLQELFKYCPEEITEEDEAVLE---------EMQLTSQR---------------TSHQLNANPLVPQIPS------YEAQNHA---------------------KAAHQMAMKLNMKL--------------DSTGSVVEPSGDIAPSSREEIPINNLPANIRYLLTTRDLRTNLSENFDVALTVKGVFM----APKDIKKLEQIGEKPLHLVLESDSPINIRSARNEICRVVKEAMKK 2770
            V+  + S +A  ST  +  K       GE   D  E  ++     EPE   +I  AL + +K++KL  V+H K+ Y+ +  N Y EVPEI KMT ++VK+ RR +  V  KGK+CPKPI  W  A VS ++LN LK    ++PTPIQ Q +P IMSG+D+IGIAKTGSGKTL++L+P++RH+ +Q  +  G+GPIA++L PTREL++QI++E +++  T   R   C C+YGG   ++QI+ LKRG E++V TPGR+ID++A NGGR  +L R T++VLDEADRMFD+GFEPQVM I+   RPDRQTVMFSATFPR++E +A+K +  PIE++V G + VC+DV Q V +L +E +K +KL+ELL  ++  G  LVFVE QE+A  L   L + G+    +HGG+ Q  R+  + +FK G + +LIATS+AARGLDVNDLM+VVNYDCPNHYEDYVHRCGRTGRAG KG +YTF+T DQE    +L+KA   +GQ +P +L   +  Y ERM++EGK +     SGFRG G++FD  EA     KK         E+  +E +   E         E   +S+R                    +  PL P+I +      ++A   A                      AA   A +LN KL              +S G+   PSGD      EE+ IN+ P N+R+ +T R++ T+L+E  DV ++V+G+++    +   +   E   E+PL+L LE+++  +I+ A+ EI R++KE + K
Sbjct:  119 VNPQLGSGNALSSTNQELAKSQKKVGRGELILDEDEQDEDMSYYPEPEERITIADALAQLQKREKLGAVDHSKIDYQPFTKNFYVEVPEIGKMTKEQVKQYRRELENVHCKGKDCPKPIKTWVQAGVSSRLLNCLKRGGFDKPTPIQCQALPVIMSGRDMIGIAKTGSGKTLAFLVPMVRHLEHQAPLENGDGPIALLLTPTRELALQIYKEAKRLGQTCGFR---CVCVYGGTGISEQIADLKRGAEVIVCTPGRMIDMLAANGGRVTNLRRTTYVVLDEADRMFDLGFEPQVMRIVDNCRPDRQTVMFSATFPRQMEVLARKALTSPIEIQVGGRSVVCSDVTQKVAVLQNEEEKVMKLLELLGIYQEEGSVLVFVEKQESADELMRVLMNYGYPCLSLHGGIDQYDRDSVITDFKRGNIRLLIATSVAARGLDVNDLMLVVNYDCPNHYEDYVHRCGRTGRAGKKGTAYTFITPDQEKNSVDLVKAFNVSGQMVPEDLYLMFNSYKERMMMEGKKVYSGGNSGFRGKGFRFDEVEAQMANDKKRFARAALGLEDSDDEGDGAGETGVDWDSKIEDMFSSKRKVIDVAKSAIVGQSGGESGSSNEPLDPKIAAQLELARFKANQVALRGGLSAIAKPGAGSIPSASRTAAELAAERLNAKLGYSKSSSNNPDSDDESNGNSGAPSGDFVRRYEEELEINDFPQNVRWRITGREMLTHLNEYCDVGVSVRGIYIPSGKSGAAVAAAESADERPLYLCLEANNERSIQMAKTEIMRIIKEELIK 899
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BLAST of Pre-mRNA-processing ATP-dependent RNA helicase PRP5 vs. TrEMBL
Match: A0A1S3JX53 (probable ATP-dependent RNA helicase DDX46 isoform X4 OS=Lingula unguis OX=7574 GN=LOC106176873 PE=4 SV=1)

HSP 1 Score: 593.578 bits (1529), Expect = 0.000e+0
Identity = 313/709 (44.15%), Postives = 442/709 (62.34%), Query Frame = 2 
Query:  812 ALFEEKKQKLPDVNHDKVYYRKYDFNLYKEVPEISKMTTKEVKELRRSM-AIVVKGKECPKPITKWSHAIVSMKILNALKYNKMNEPTPIQSQTIPAIMSGKDVIGIAKTGSGKTLSYLLPLIRHIHNQPNVTVGEGPIAIVLCPTRELSIQIHQEIEKITYALRDVNCGCIYGGADTAQQISRLKRGVEIVVGTPGRIIDIMATNGGRNLSLSRCTFIVLDEADRMFDMGFEPQVMAIISRIRPDRQTVMFSATFPRRIEAVAKKIMKEPIEVRVDGGNKVCTDVVQHVYLLDENDKFLKLVELLSEFKYRGKSLVFVETQETAQILSSNLTHQGFEVSMIHGGLTQEKREEGMFNFKSGTVPILIATSIAARGLDVNDLMMVVNYDCPNHYEDYVHRCGRTGRAGNKGYSYTFVTSDQEVMIGNLIKALKENGQEIPGELTEAYARYTERMVLEGKTIKAPSGFRGHGYKFDAAEA-MKEKGKKLQELFKYCPEEITEEDEAV-----LEEMQLTSQRTSH--------------------------------------------QLNANPLVPQIPSYEAQNHAKA-AHQMAMKLNMKLDSTGSVVEPSGDIAPSSRE------EIPINNLPANIRYLLTTRDLRTNLSENFDVALTVKGVFMAPKDIKKLEQIGEKPLHLVLESDSPINIRSARNEICRVVKEAM 2764
            A  ++KK++   ++H K+YY  +  + Y EVPE++KM+ +EV +LR  +  I V+GK CPKPI  W+   VS KI+  LK     +PTPIQ+Q IPAIMSG+DVIGIAKTGSGKTL++LLP++RH+ +QP +  G+G IAI+L PTREL++QI +E +K T  L  +   C+YGG   ++QI+ LKRG EI+V TPGR+ID++A N GR  +  RCTF+VLDEADRMFDMGFEPQVM I+  IRPDRQTVMFSATFPR++EA+A+KI+ +PIEV+V G + VC DV QHV ++D++ KF KL+ELL  ++ +G  LVFV+ QE A  L  NL    +    +HGG+ Q  R+  + +FK G V +L+ATS+AARGLDV  L++VVNYDCPNHYEDYVHRCGRTGRAGNKG++YTF+T +QE    ++IKAL+++G  +P +L + +  Y  R   EGK IK+ SGFRG G+KFD  EA + ++ KKLQ+      ++  EED  +     +E+M  +  R +                                             Q  A  ++  +PS   Q  AK  A QMA K+N K+       E                 E+ IN+ P   R+ +T+++    + E  +  +TV+G +  P  + K E   E+ L+L +E+ S ++I+ A+ EI R++KE +
Sbjct:  290 AGMQKKKKEFLAIDHSKIYYGPFKKDFYVEVPELTKMSQEEVDQLRDELEGIKVRGKGCPKPIRNWAQCGVSKKIMECLKRYDYEKPTPIQAQAIPAIMSGRDVIGIAKTGSGKTLAFLLPMLRHVLDQPPLEEGDGSIAIILTPTRELAMQITKECKKFTKNL-GLQAVCVYGGTGISEQIAELKRGAEIIVCTPGRMIDMLAANNGRVTNCRRCTFVVLDEADRMFDMGFEPQVMRIVDNIRPDRQTVMFSATFPRQMEALARKILTKPIEVQVGGRSVVCKDVEQHVVVIDDDSKFFKLLELLGVYQEQGSVLVFVDKQEHADELMKNLMKHSYPCMSLHGGIDQYDRDSTITDFKQGNVKLLVATSVAARGLDVKHLILVVNYDCPNHYEDYVHRCGRTGRAGNKGFAYTFITPEQERYANDIIKALEQSGAVVPADLQKLWDDYKARAEAEGKKIKSSSGFRGKGFKFDETEAHLADERKKLQKA-ALGLQDSDEEDAGIDIDQQIEDMFASKTRVTDVHQPMINQQAQPTASNQQKLELAKRLASMINRQKNLGAEAQDITQQAAASILQGLPSQAPQVSAKTIAEQMAEKINAKIGYRPPAEEEKEGQEQQGETFKRYELELEINDFPQTARWKVTSKEALAQICEYSEAGITVRGTYFPPGKLPKEE---ERKLYLAIEATSELSIQKAKTEITRLIKEEL 993
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BLAST of Pre-mRNA-processing ATP-dependent RNA helicase PRP5 vs. TrEMBL
Match: A0A1S3JXV8 (probable ATP-dependent RNA helicase DDX46 isoform X1 OS=Lingula unguis OX=7574 GN=LOC106176873 PE=4 SV=1)

HSP 1 Score: 593.193 bits (1528), Expect = 0.000e+0
Identity = 313/709 (44.15%), Postives = 442/709 (62.34%), Query Frame = 2 
Query:  812 ALFEEKKQKLPDVNHDKVYYRKYDFNLYKEVPEISKMTTKEVKELRRSM-AIVVKGKECPKPITKWSHAIVSMKILNALKYNKMNEPTPIQSQTIPAIMSGKDVIGIAKTGSGKTLSYLLPLIRHIHNQPNVTVGEGPIAIVLCPTRELSIQIHQEIEKITYALRDVNCGCIYGGADTAQQISRLKRGVEIVVGTPGRIIDIMATNGGRNLSLSRCTFIVLDEADRMFDMGFEPQVMAIISRIRPDRQTVMFSATFPRRIEAVAKKIMKEPIEVRVDGGNKVCTDVVQHVYLLDENDKFLKLVELLSEFKYRGKSLVFVETQETAQILSSNLTHQGFEVSMIHGGLTQEKREEGMFNFKSGTVPILIATSIAARGLDVNDLMMVVNYDCPNHYEDYVHRCGRTGRAGNKGYSYTFVTSDQEVMIGNLIKALKENGQEIPGELTEAYARYTERMVLEGKTIKAPSGFRGHGYKFDAAEA-MKEKGKKLQELFKYCPEEITEEDEAV-----LEEMQLTSQRTSH--------------------------------------------QLNANPLVPQIPSYEAQNHAKA-AHQMAMKLNMKLDSTGSVVEPSGDIAPSSRE------EIPINNLPANIRYLLTTRDLRTNLSENFDVALTVKGVFMAPKDIKKLEQIGEKPLHLVLESDSPINIRSARNEICRVVKEAM 2764
            A  ++KK++   ++H K+YY  +  + Y EVPE++KM+ +EV +LR  +  I V+GK CPKPI  W+   VS KI+  LK     +PTPIQ+Q IPAIMSG+DVIGIAKTGSGKTL++LLP++RH+ +QP +  G+G IAI+L PTREL++QI +E +K T  L  +   C+YGG   ++QI+ LKRG EI+V TPGR+ID++A N GR  +  RCTF+VLDEADRMFDMGFEPQVM I+  IRPDRQTVMFSATFPR++EA+A+KI+ +PIEV+V G + VC DV QHV ++D++ KF KL+ELL  ++ +G  LVFV+ QE A  L  NL    +    +HGG+ Q  R+  + +FK G V +L+ATS+AARGLDV  L++VVNYDCPNHYEDYVHRCGRTGRAGNKG++YTF+T +QE    ++IKAL+++G  +P +L + +  Y  R   EGK IK+ SGFRG G+KFD  EA + ++ KKLQ+      ++  EED  +     +E+M  +  R +                                             Q  A  ++  +PS   Q  AK  A QMA K+N K+       E                 E+ IN+ P   R+ +T+++    + E  +  +TV+G +  P  + K E   E+ L+L +E+ S ++I+ A+ EI R++KE +
Sbjct:  301 AGMQKKKKEFLAIDHSKIYYGPFKKDFYVEVPELTKMSQEEVDQLRDELEGIKVRGKGCPKPIRNWAQCGVSKKIMECLKRYDYEKPTPIQAQAIPAIMSGRDVIGIAKTGSGKTLAFLLPMLRHVLDQPPLEEGDGSIAIILTPTRELAMQITKECKKFTKNL-GLQAVCVYGGTGISEQIAELKRGAEIIVCTPGRMIDMLAANNGRVTNCRRCTFVVLDEADRMFDMGFEPQVMRIVDNIRPDRQTVMFSATFPRQMEALARKILTKPIEVQVGGRSVVCKDVEQHVVVIDDDSKFFKLLELLGVYQEQGSVLVFVDKQEHADELMKNLMKHSYPCMSLHGGIDQYDRDSTITDFKQGNVKLLVATSVAARGLDVKHLILVVNYDCPNHYEDYVHRCGRTGRAGNKGFAYTFITPEQERYANDIIKALEQSGAVVPADLQKLWDDYKARAEAEGKKIKSSSGFRGKGFKFDETEAHLADERKKLQKA-ALGLQDSDEEDAGIDIDQQIEDMFASKTRVTDVHQPMINQQAQPTASNQQKLELAKRLASMINRQKNLGAEAQDITQQAAASILQGLPSQAPQVSAKTIAEQMAEKINAKIGYRPPAEEEKEGQEQQGETFKRYELELEINDFPQTARWKVTSKEALAQICEYSEAGITVRGTYFPPGKLPKEE---ERKLYLAIEATSELSIQKAKTEITRLIKEEL 1004
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BLAST of Pre-mRNA-processing ATP-dependent RNA helicase PRP5 vs. TrEMBL
Match: A0A3B5LBR6 (DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 OS=Xiphophorus couchianus OX=32473 PE=4 SV=1)

HSP 1 Score: 592.808 bits (1527), Expect = 0.000e+0
Identity = 312/714 (43.70%), Postives = 452/714 (63.31%), Query Frame = 2 
Query:  722 KIGEFTDDHIEDTDEYHQTVEPETLESITQALFEEKKQKLPDVNHDKVYYRKYDFNLYKEVPEISKMTTKEVKELRRSM-AIVVKGKECPKPITKWSHAIVSMKILNALKYNKMNEPTPIQSQTIPAIMSGKDVIGIAKTGSGKTLSYLLPLIRHIHNQPNVTVGEGPIAIVLCPTRELSIQIHQEIEKITYALRDVNCGCIYGGADTAQQISRLKRGVEIVVGTPGRIIDIMATNGGRNLSLSRCTFIVLDEADRMFDMGFEPQVMAIISRIRPDRQTVMFSATFPRRIEAVAKKIMKEPIEVRVDGGNKVCTDVVQHVYLLDENDKFLKLVELLSEFKYRGKSLVFVETQETAQILSSNLTHQGFEVSMIHGGLTQEKREEGMFNFKSGTVPILIATSIAARGLDVNDLMMVVNYDCPNHYEDYVHRCGRTGRAGNKGYSYTFVTSDQEVMIGNLIKALKENGQEIPGELTEAYARYTERMVLEGKTIKAPSGFRGHGYKFDAAE-AMKEKGKKLQELFKYCPEEITEEDEAVLEEMQLTS------------------------QRTSHQLNANPLVPQIPSYEAQNHAKAAHQMAMKLNMKLDST-------GSVVEPSGDIAPSSREEIPINNLPANIRYLLTTRDLRTNLSENFDVALTVKGVFMAPKDIKKLEQIGEKPLHLVLESDSPINIRSARNEICRVVKEAM 2764
            K GE  ++  +D  EY    E   L++       ++++ L  V+H K+ Y  Y  N Y EVPE++KMTT+EV   R  +  I VKGK CPKPI  W    VSMKILN+LK     +PTPIQ+Q IPAIMSG+D+IGIAKTGSGKT+++LLP+ RHI +Q  +  GEGPI++++ PTREL++QI +E +K +  L  +   C+YGG   ++QI+ LKRG EI+V TPGR+ID++  N GR  +L R T++VLDEADRMFDMGFEPQVM I+  +RPDRQTVMFSATFPR +EA+A++I+ +PIEV+V G + VC+DV QHV ++DE  KFLKL+E+L  ++ +G  ++FV+ QE A  L  +L    +    +HGG+ Q  R+  + +FK+G   +++ATS+AARGLDV  L++VVNY+CPNHYEDYVHR GRTGRAGNKGY+YTF+T DQ    G+++KAL+ +G  +P EL + +A + ++   EGK IK+ SGF G G+KFD  E A+  + KKLQ+      ++  +ED A+  E Q+ S                        Q T+  L  +P++   PS  A+     A Q+A K+N KL+ T               +      EE+ IN+ P   R+ +T+++    + E  + A+T++G +  P    K  + GE+ ++L +ES S + ++ A+ EI R++KE +
Sbjct:  222 KKGELMEND-QDAMEYSSEEEEVDLQTALTGFQTKQRKVLEPVDHTKIQYEPYRKNFYVEVPELAKMTTEEVNAYRLELEGITVKGKGCPKPIRTWVQCGVSMKILNSLKKQAYEKPTPIQAQAIPAIMSGRDLIGIAKTGSGKTIAFLLPMFRHIMDQRPLEEGEGPISVIMTPTRELALQITKECKKFSKPL-GLRVVCVYGGTGISEQIAELKRGAEIIVCTPGRMIDMLGANSGRVTNLRRVTYVVLDEADRMFDMGFEPQVMRIVDNVRPDRQTVMFSATFPRAMEALARRILAKPIEVQVGGRSVVCSDVEQHVLVIDEEKKFLKLLEILGHYQEKGSVIIFVDKQEHADGLLKDLMKASYPCLSLHGGIDQYDRDSIINDFKTGVCRLMVATSVAARGLDVKQLILVVNYNCPNHYEDYVHRAGRTGRAGNKGYAYTFITEDQARYAGDILKALELSGSAVPPELEQLWASFKDQQKAEGKVIKSSSGFSGKGFKFDETEHALANERKKLQKA-ALGLQDSDDEDGALDIEEQIESMFNSKKRLLPNWLCVLLYLQDVMQQATNAILRGDPIM--TPSVSAKT---IAEQLAEKINAKLNYTPVEKLEEERQAAEQAETVKRYEEELEINDFPQTARWKVTSKEALQRIGEYSEAAITIRGTYFPP---GKEPKEGERKIYLAIESASELAVQKAKTEITRLIKEEL 924
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BLAST of Pre-mRNA-processing ATP-dependent RNA helicase PRP5 vs. TrEMBL
Match: A0A0R3T2P0 (Uncharacterized protein OS=Rodentolepis nana OX=102285 PE=4 SV=1)

HSP 1 Score: 592.423 bits (1526), Expect = 0.000e+0
Identity = 327/767 (42.63%), Postives = 470/767 (61.28%), Query Frame = 2 
Query:  728 GEFTDDHIEDTDEYHQTVEPETLESITQALFE-EKKQKLPDVNHDKVYYRKYDFNLYKEVPEISKMTTKEVKELRRSMAIV-VKGKECPKPITKWSHAIVSMKILNALKYNKMNEPTPIQSQTIPAIMSGKDVIGIAKTGSGKTLSYLLPLIRHIHNQPNVTVGEGPIAIVLCPTRELSIQIHQEIEKI--TYALRDVNCGCIYGGADTAQQISRLKRGVEIVVGTPGRIIDIMATNGGRNLSLSRCTFIVLDEADRMFDMGFEPQVMAIISRIRPDRQTVMFSATFPRRIEAVAKKIMKEPIEVRVDGGNKVCTDVVQHVYLL-DENDKFLKLVELLSEFKYRGKSLVFVETQETAQILSSNLTHQGFEVSMIHGGLTQEKREEGMFNFKSGTVPILIATSIAARGLDVNDLMMVVNYDCPNHYEDYVHRCGRTGRAGNKGYSYTFVTSDQEVMIGNLIKALKENGQEIPGELTEAYARYTERMVLEGKTIKAP--SGFRGHGYKFDAAEAMKEKGKKLQELFKYCPEEITEEDEAVLE---------EMQLTSQR-------------TSHQLNAN-PLVPQIPS------YEAQNHA---------------------KAAHQMAMKLNMKL--------------DSTGSVVEPSGDIAPSSREEIPINNLPANIRYLLTTRDLRTNLSENFDVALTVKGVFMAPKDIKKL----EQIGEKPLHLVLESDSPINIRSARNEICRVVKEAMKK*INLSANKMFY 2803
            GE   D  E  ++     EPE   +I  AL + +K++KL  V+H K+ Y+ +  N Y EVPEI+KMT ++VK+ RR +  V   GK+CPKPI  W  A VS ++LN LK +   +PTPIQ Q +P IMSG+D+IGIAKTGSGKTL++L+P++RH+ +Q  +  G+GPIA++L PTREL++QI++E +++  T   R   C C+YGG   ++QI+ LKRG E++V TPGR+ID++A NGGR  +L R T++VLDEADRMFD+GFEPQVM I+   RPDRQTVMFSATFPR++E +A+K +  PIE++V G + VC+DV Q V +L +E +K +KL+ELL  ++  G  LVFVE QE+A  L   L + G+    +HGG+ Q  R+  + +FK G + +LIATS+AARGLDVNDL++VVNYDCPNHYEDYVHRCGRTGRAG KG +YTF+T DQE    +L+KA   +GQ +P +L   +  Y ERM++EGK + +   SGFRG G++FD  EA     KK         E+  +E +   E         E   +S+R             +    ++N PL P+I +      ++A   A                      AA   A +LN KL              +  G+   PSGD      EE+ IN+ P N+R+ +T R++ T+L+E  DV ++V+G+++ P          +   E+PL+L LE+++  +I+ A+ EI R++KE + K + L    +FY
Sbjct:  176 GELILDEDEQDEDMSYYPEPEERITIADALAQLQKREKLGAVDHSKIDYQPFTKNFYVEVPEIAKMTKEQVKQYRRELENVHCNGKDCPKPIKTWVQAGVSSRLLNCLKRSGFEKPTPIQCQALPVIMSGRDMIGIAKTGSGKTLAFLVPMVRHLEHQAPLENGDGPIALLLTPTRELALQIYKEAKRLGQTCGFR---CVCVYGGTGISEQIADLKRGAEVIVCTPGRMIDMLAANGGRVTNLRRTTYVVLDEADRMFDLGFEPQVMRIVDNCRPDRQTVMFSATFPRQMEVLARKALTSPIEIQVGGRSVVCSDVTQKVAVLQNEEEKVMKLLELLGVYQEEGSVLVFVEKQESADELMRVLMNYGYPCLSLHGGIDQYDRDSVITDFKKGNIRLLIATSVAARGLDVNDLVLVVNYDCPNHYEDYVHRCGRTGRAGKKGTAYTFITPDQEKNSLDLVKAFNVSGQMVPEDLYLMFNAYKERMMMEGKKVYSGGNSGFRGKGFRFDEVEAQMANDKKRFARAALGLEDSDDEGDGAGETGVDWDSKIENMFSSKRKVIDVAKSTIVGQSGDGGSSNEPLDPKIAAQLELARFKANQVALRGGLSAIAKSGVGSTPSASRTAAELAAERLNAKLGYSKSSSNNPDSDDEGNGNSGAPSGDFVRRYEEELDINDFPQNVRWRITGREMLTHLNEYCDVGVSVRGIYIPPGKSGPPPGTADSADERPLYLCLEANNERSIQMAKTEIMRIIKEELIKLVGLFKACLFY 939
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BLAST of Pre-mRNA-processing ATP-dependent RNA helicase PRP5 vs. Ensembl Cavefish
Match: ddx46 (DEAD-box helicase 46 [Source:NCBI gene;Acc:103041720])

HSP 1 Score: 548.895 bits (1413), Expect = 3.600e-178
Identity = 262/517 (50.68%), Postives = 367/517 (70.99%), Query Frame = 2 
Query:  728 GEFTDDHIEDTDEYHQTVEPETLESITQALFEEKKQKLPDVNHDKVYYRKYDFNLYKEVPEISKMTTKEVKELRRSM-AIVVKGKECPKPITKWSHAIVSMKILNALKYNKMNEPTPIQSQTIPAIMSGKDVIGIAKTGSGKTLSYLLPLIRHIHNQPNVTVGEGPIAIVLCPTRELSIQIHQEIEKITYALRDVNCGCIYGGADTAQQISRLKRGVEIVVGTPGRIIDIMATNGGRNLSLSRCTFIVLDEADRMFDMGFEPQVMAIISRIRPDRQTVMFSATFPRRIEAVAKKIMKEPIEVRVDGGNKVCTDVVQHVYLLDENDKFLKLVELLSEFKYRGKSLVFVETQETAQILSSNLTHQGFEVSMIHGGLTQEKREEGMFNFKSGTVPILIATSIAARGLDVNDLMMVVNYDCPNHYEDYVHRCGRTGRAGNKGYSYTFVTSDQEVMIGNLIKALKENGQEIPGELTEAYARYTERMVLEGKTIKAPSGFRGHGYKFDAAE-AMKEKGKKLQE 2272
            GE  ++  +D  EY    E   L++       ++++ L  V+H K+ Y  Y  N Y EVPE+++MT +EV E R  +  I VKGK CPKPI  W     SMK+LNALK +   +PTPIQSQ IPAIMSG+D+IGIAKTGSGKT+++LLP+ RHI +Q  +  GEGPIA+++ PTREL++QI +E +K +  L  +   C+YGG   ++QI+ LKRG EI+V TPGR+ID++  N GR  +L R T++V+DEADRMFDMGFEPQVM I+  +RPDRQTVMFSATFPR +EA+A++I+ +P+EV+V G + VC+DV QHV +++E+ KFLKL+E+L  ++ +G  ++FV+ QE A  L  +L    +    +HGG+ Q  R+  + +FK+G   +++ATS+AARGLDV  L++VVNY+CPNHYEDYVHR GRTGRAGNKG++YTF+T +Q    G++IKAL+ +G  +P EL + +A + E+   EGK IK+ SGF G G+KFD  E A+  + KKLQ+
Sbjct:  284 GELMEND-QDAMEYSSEEEEVDLQTALTGYQTKQRKILEPVDHQKIQYESYRKNFYVEVPELARMTPEEVNEYRLELEGITVKGKGCPKPIKTWVQCGTSMKVLNALKKHNYEKPTPIQSQAIPAIMSGRDLIGIAKTGSGKTIAFLLPMFRHILDQRPLEEGEGPIAVIMTPTRELALQITKECKKFSKPL-GLRVVCVYGGTGISEQIAELKRGAEIIVCTPGRMIDMLGANSGRVTNLRRVTYVVVDEADRMFDMGFEPQVMRIMDNVRPDRQTVMFSATFPRAMEALARRILNKPVEVQVGGRSVVCSDVEQHVIVIEEDKKFLKLLEILGHYQEKGSVIIFVDKQEHADGLLKDLMKASYPCMSLHGGIDQYDRDSIINDFKNGACRLMVATSVAARGLDVKQLILVVNYNCPNHYEDYVHRAGRTGRAGNKGFAYTFITDEQARYAGDIIKALELSGSAVPSELEQLWATFKEQQKAEGKIIKSSSGFSGKGFKFDETEHALANERKKLQK 798

HSP 2 Score: 55.0694 bits (131), Expect = 4.823e-7
Identity = 34/120 (28.33%), Postives = 65/120 (54.17%), Query Frame = 2 
Query: 2426 AHQMAMKLNMKLDSTG-SVVEPSGDIAPSSR------EEIPINNLPANIRYLLTTRDLRTNLSENFDVALTVKGVFMAPKDIKKLEQIGEKPLHLVLESDSPINIRSARNEICRVVKEAM 2764
            A Q+A K+N KL+ T    +E     A  +       EE+ IN+ P   R+ +T+++    + E  + A+T++G +  P    K  + GE+ ++L +ES + + ++ A+ EI R++KE +
Sbjct:  917 AEQLAEKINAKLNYTPVEKLEEERQAAEQAESIKRYEEELEINDFPQTARWKVTSKEALQRIGEYSEAAITIRGTYFPPG---KEPKEGERKIYLAIESANELAVQKAKAEITRLIKEEL 1033
[Close]
BLAST of Pre-mRNA-processing ATP-dependent RNA helicase PRP5 vs. Ensembl Cavefish
Match: ddx46 (DEAD-box helicase 46 [Source:NCBI gene;Acc:103041720])

HSP 1 Score: 507.294 bits (1305), Expect = 7.307e-163
Identity = 250/517 (48.36%), Postives = 353/517 (68.28%), Query Frame = 2 
Query:  728 GEFTDDHIEDTDEYHQTVEPETLESITQALFEEKKQKLPDVNHDKVYYRKYDFNLYKEVPEISKMTTKEVKELRRSM-AIVVKGKECPKPITKWSHAIVSMKILNALKYNKMNEPTPIQSQTIPAIMSGKDVIGIAKTGSGKTLSYLLPLIRHIHNQPNVTVGEGPIAIVLCPTRELSIQIHQEIEKITYALRDVNCGCIYGGADTAQQISRLKRGVEIVVGTPGRIIDIMATNGGRNLSLSRCTFIVLDEADRMFDMGFEPQVMAIISRIRPDRQTVMFSATFPRRIEAVAKKIMKEPIEVRVDGGNKVCTDVVQHVYLLDENDKFLKLVELLSEFKYRGKSLVFVETQETAQILSSNLTHQGFEVSMIHGGLTQEKREEGMFNFKSGTVPILIATSIAARGLDVNDLMMVVNYDCPNHYEDYVHRCGRTGRAGNKGYSYTFVTSDQEVMIGNLIKALKENGQEIPGELTEAYARYTERMVLEGKTIKAPSGFRGHGYKFDAAE-AMKEKGKKLQE 2272
            GE  ++  +D  EY    E   L++       ++++ L  V+H K+ Y  Y  N Y EVPE+++MT +EV E R  +  I VKGK CPKPI  W     SMK+LNALK +   +PTPIQSQ IPAIMSG+D+IGIAKTGSGKT+++LLP+ RHI +Q  +  GEGPIA+++ PTREL++QI +E +K +  L  +   C+YGG   ++Q   L   +  V+G  GR+ +           L R T++V+DEADRMFDMGFEPQVM I+  +RPDRQTVMFSATFPR +EA+A++I+ +P+EV+V G + VC+DV QHV +++E+ KFLKL+E+L  ++ +G  ++FV+ QE A  L  +L    +    +HGG+ Q  R+  + +FK+G   +++ATS+AARGLDV  L++VVNY+CPNHYEDYVHR GRTGRAGNKG++YTF+T +Q    G++IKAL+ +G  +P EL + +A + E+   EGK IK+ SGF G G+KFD  E A+  + KKLQ+
Sbjct:  243 GELMEND-QDAMEYSSEEEEVDLQTALTGYQTKQRKILEPVDHQKIQYESYRKNFYVEVPELARMTPEEVNEYRLELEGITVKGKGCPKPIKTWVQCGTSMKVLNALKKHNYEKPTPIQSQAIPAIMSGRDLIGIAKTGSGKTIAFLLPMFRHILDQRPLEEGEGPIAVIMTPTRELALQITKECKKFSKPL-GLRVVCVYGGTGISEQNVFLTLCLCFVLGCLGRVTN-----------LRRVTYVVVDEADRMFDMGFEPQVMRIMDNVRPDRQTVMFSATFPRAMEALARRILNKPVEVQVGGRSVVCSDVEQHVIVIEEDKKFLKLLEILGHYQEKGSVIIFVDKQEHADGLLKDLMKASYPCMSLHGGIDQYDRDSIINDFKNGACRLMVATSVAARGLDVKQLILVVNYNCPNHYEDYVHRAGRTGRAGNKGFAYTFITDEQARYAGDIIKALELSGSAVPSELEQLWATFKEQQKAEGKIIKSSSGFSGKGFKFDETEHALANERKKLQK 746

HSP 2 Score: 54.6842 bits (130), Expect = 5.784e-7
Identity = 34/121 (28.10%), Postives = 64/121 (52.89%), Query Frame = 2 
Query: 2426 AHQMAMKLNMKLDST--------GSVVEPSGDIAPSSREEIPINNLPANIRYLLTTRDLRTNLSENFDVALTVKGVFMAPKDIKKLEQIGEKPLHLVLESDSPINIRSARNEICRVVKEAM 2764
            A Q+A K+N KL+ T            E +  I     EE+ IN+ P   R+ +T+++    + E  + A+T++G +  P    K  + GE+ ++L +ES + + ++ A+ EI R++KE +
Sbjct:  865 AEQLAEKINAKLNYTPVEKLEEERQAAEQAESI-KRYEEELEINDFPQTARWKVTSKEALQRIGEYSEAAITIRGTYFPPG---KEPKEGERKIYLAIESANELAVQKAKAEITRLIKEEL 981
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BLAST of Pre-mRNA-processing ATP-dependent RNA helicase PRP5 vs. Ensembl Cavefish
Match: DDX5 (probable ATP-dependent RNA helicase DDX5 [Source:NCBI gene;Acc:103046784])

HSP 1 Score: 367.081 bits (941), Expect = 3.427e-114
Identity = 183/420 (43.57%), Postives = 273/420 (65.00%), Query Frame = 2 
Query:  875 KYDFNLYKEVPEISKMTTKEVKELRRSMAIVVKGKECPKPITKWSHAIVSMKILNALKYNKMNEPTPIQSQTIPAIMSGKDVIGIAKTGSGKTLSYLLPLIRHIHNQPNVTVGEGPIAIVLCPTRELSIQIHQEIEKITYALRDVNCGCIYGGADTAQQISRLKRGVEIVVGTPGRIIDIMATNGGRNLSLSRCTFIVLDEADRMFDMGFEPQVMAIISRIRPDRQTVMFSATFPRRIEAVAKKIMKEPIEVRVDGGNKVCT--DVVQHVYLLDENDKFLKLVELLSEF--KYRGKSLVFVETQETAQILSSNLTHQGFEVSMIHGGLTQEKREEGMFNFKSGTVPILIATSIAARGLDVNDLMMVVNYDCPNHYEDYVHRCGRTGRAGNKGYSYTFVTSDQEVMIGNLIKALKENGQEI 2122
            K++ N YKE P+I++ + +EV++ RR+  + VKG++CPKP+ K++ A     ++  +     +EPTPIQ+Q  P  +SGKD++GIA+TGSGKTL+YLLP I HI++QP +  G+GPI +VL PTREL+ Q+ Q   +   A R +   CIYGGA    QI  L+RGVEI + TPGR+ID +        +L RCT++VLDEADRM DMGFEPQ+  I+ +IRPDRQT+M+SAT+P+ +  +A+  +KE +++ + G  ++    +++Q V + ++ +K  KL+ LL E   +   K+++FVET+     L+  +   G+    IHG  +Q++R+  +  FK G   ILIAT +A+RGLDV D+  V+NYD PN  EDY+HR GRT R+   G +YTF T +      +LI  L+E  Q I
Sbjct:   53 KFEKNFYKEHPDITRRSMQEVEQYRRAKEVTVKGRDCPKPVMKFNEATFPNYVMEVINKQAWSEPTPIQAQGWPLALSGKDMVGIAQTGSGKTLAYLLPAIVHINHQPFLEHGDGPICLVLAPTRELAQQVQQVAAEYGRASR-LKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLEAG---KTNLRRCTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAEDFLKEYVQINI-GALQLSANHNILQIVDVCNDGEKDDKLIRLLEEIMSEKENKTIIFVETKRRCDELTRRMRRDGWPAMGIHGDKSQQERDWVLNEFKYGKACILIATDVASRGLDVEDVKFVINYDYPNSSEDYIHRIGRTARSQKTGTAYTFFTPNNMKQANDLISVLREANQAI 467
[Close]
BLAST of Pre-mRNA-processing ATP-dependent RNA helicase PRP5 vs. Ensembl Cavefish
Match: ddx5 (probable ATP-dependent RNA helicase DDX5 [Source:NCBI gene;Acc:103024726])

HSP 1 Score: 365.155 bits (936), Expect = 1.659e-113
Identity = 182/420 (43.33%), Postives = 273/420 (65.00%), Query Frame = 2 
Query:  875 KYDFNLYKEVPEISKMTTKEVKELRRSMAIVVKGKECPKPITKWSHAIVSMKILNALKYNKMNEPTPIQSQTIPAIMSGKDVIGIAKTGSGKTLSYLLPLIRHIHNQPNVTVGEGPIAIVLCPTRELSIQIHQEIEKITYALRDVNCGCIYGGADTAQQISRLKRGVEIVVGTPGRIIDIMATNGGRNLSLSRCTFIVLDEADRMFDMGFEPQVMAIISRIRPDRQTVMFSATFPRRIEAVAKKIMKEPIEVRVDGGNKVCT--DVVQHVYLLDENDKFLKLVELLSEF--KYRGKSLVFVETQETAQILSSNLTHQGFEVSMIHGGLTQEKREEGMFNFKSGTVPILIATSIAARGLDVNDLMMVVNYDCPNHYEDYVHRCGRTGRAGNKGYSYTFVTSDQEVMIGNLIKALKENGQEI 2122
            K++ N Y+E P++ + T +EV++ RRS  I VKG+ECPKP+ ++  +     +++ +      +PTPIQ+Q  P  +SG+D++GIA+TGSGKTLSYLLP I HI++QP +  G+GPI +VL PTREL+ Q+ Q   +   A R +   CIYGGA    QI  L+RGVEI + TPGR+ID +        +L RCT++VLDEADRM DMGFEPQ+  I+ +IRPDRQT+M+SAT+P+ +  +A+  +KE +++ V G  ++    +++Q V + ++ +K  KL+ LL E   +   K+++FVET+     L+  +   G+    IHG  +Q++R+  +  FK G  PILIAT +A+RGLDV D+  V+N+D PN+ EDY+HR GRT R+   G +YTF T +      +L+  L+E  Q I
Sbjct:   55 KFEKNFYQEHPDVGRRTPQEVEQYRRSKEITVKGRECPKPVMRFHESNFPSYVMDVISKQNWTDPTPIQAQGWPLALSGQDMVGIAQTGSGKTLSYLLPAIVHINHQPFLERGDGPICLVLAPTRELAQQVQQVAAEYGRASR-LKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLEAG---KTNLRRCTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAEDFLKEYVQINV-GALQLSANHNILQIVDVCNDGEKEDKLLRLLEEIMSEKENKTIIFVETKRRCDDLTRRMRRDGWPAMGIHGDKSQQERDWVLNEFKFGKAPILIATDVASRGLDVEDVKFVINFDYPNNSEDYIHRIGRTARSQKTGTAYTFFTPNNMKQAHDLVSVLREANQAI 469
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BLAST of Pre-mRNA-processing ATP-dependent RNA helicase PRP5 vs. Ensembl Cavefish
Match: ddx42 (DEAD-box helicase 42 [Source:NCBI gene;Acc:103044432])

HSP 1 Score: 360.533 bits (924), Expect = 2.737e-108
Identity = 186/468 (39.74%), Postives = 284/468 (60.68%), Query Frame = 2 
Query:  839 LPDVNHDKVYYRKYDFNLYKEVPEISKMTTKEVKELRRSMAIVVKGKECPKPITKWSHAIVSMKILNALKYNKMNEPTPIQSQTIPAIMSGKDVIGIAKTGSGKTLSYLLPLIRHIHNQPNVTVGEGPIAIVLCPTRELSIQIHQEIEKI--TYALRDVNCGCIYGGADTAQQISRLKRGVEIVVGTPGRIIDIMATNGGRNLSLSRCTFIVLDEADRMFDMGFEPQVMAIISRIRPDRQTVMFSATFPRRIEAVAKKIMKEPIEVRVDGGNKVCTDVVQHVYLL-DENDKFLKLVELLSEFKYRGKSLVFVETQETAQILSSNLTHQGFEVSMIHGGLTQEKREEGMFNFKSGTVPILIATSIAARGLDVNDLMMVVNYDCPNHYEDYVHRCGRTGRAGNKGYSYTFVTSDQEVMIGNLIKALKENGQEIPGELTE---AYARYTERMVLEGKTIKAPSGFRGHGYK 2224
            LP ++H ++ Y  ++ N Y E  E++ +T  +V ELR+ + + V G   PKP T ++H     +++N ++ ++  +PTPIQ Q +P  + G+D+IGIAKTGSGKT +++ P++ HI +Q  +  G+GPIA+++CPTREL  QIH E ++    Y LR V    +YGG    +Q   L+ G EIVV TPGR+ID +     +  SL R T++V DEADRMFDMGFE QV +I S IRPDRQT++FSATF ++IE +A+ I+ +PI V      +   DV Q V +L +  DK++ L   L EF   G  L+FV  +     L++NL  +G+ + ++HG + Q +R + + +FK  ++P+L+AT +AARGLD+  +  VVNYD     + + HR GRTGRAG KG +YT +T       G+L++ L+   Q +  +L +     + + +     GK  K   G  G GY+
Sbjct:  198 LPPIDHSEIDYPPFEKNFYIEHEELNSLTGTQVVELRQKLNLRVSGAAPPKPCTSFAHFNFDEQLMNQIRKSEYTKPTPIQCQGVPIALGGRDMIGIAKTGSGKTAAFIWPMLVHIMDQKELEQGDGPIAVIVCPTRELCQQIHTECKRFGKVYGLRSV---AVYGGGSMWEQAKALQEGAEIVVCTPGRLIDHVKK---KATSLQRVTYLVFDEADRMFDMGFEYQVRSIASHIRPDRQTLLFSATFRKKIEKLARDILIDPIRVVQGDIGEANEDVTQLVEVLPNGTDKWVWLTRRLVEFTSSGSVLIFVTKKANCDELATNLQQEGYSLGLLHGDMDQSERNKVISDFKKKSLPVLVATDVAARGLDIPSIRTVVNYDVARDIDTHTHRIGRTGRAGEKGVAYTLLTQKDTTFAGDLVRNLEGANQSVSKDLLDLAMQNSWFRKSRFKGGKGKKLNIGGGGLGYR 659
[Close]
BLAST of Pre-mRNA-processing ATP-dependent RNA helicase PRP5 vs. Ensembl Sea Lamprey
Match: ddx46 (DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Source:NCBI gene;Acc:321948])

HSP 1 Score: 563.918 bits (1452), Expect = 0.000e+0
Identity = 310/744 (41.67%), Postives = 452/744 (60.75%), Query Frame = 2 
Query:  728 GEFTDDHIEDTDEYHQTVEPETLESITQALFEEKKQKLPDV-NHDKVYYRKYDFNLYKEVPEISKMTTKEVKELRRSM-AIVVKGKECPKPITKWSHAIVSMKILNALKYNKMNEPTPIQSQTIPAIMSGKDVIGIAKTGSGKTLSYLLPLIRHIHNQPNVTVGEGPIAIVLCPTRELSIQIHQEIEKIT--YALRDVNCGCIYGGADTAQQISRLKRGVEIVVGTPGRIIDIMATNGGRNLSLSRCTFIVLDEADRMFDMGFEPQVMAIISRIRPDRQTVMFSATFPRRIEAVAKKIMKEPIEVRVDGGNKVCTDVVQHVYLLDENDKFLKLVELLSEFKYRGKSLVFVETQETAQILSSNLTHQGFEVSMIHGGLTQEKREEGMFNFKSGTVPILIATSIAARGLDVNDLMMVVNYDCPNHYEDYVHRCGRTGRAGNKGYSYTFVTSDQEVMIGNLIKALKENGQEIPGELTEAYARYTERMVLEGKTIKAPSGFRGHGYKFDAAE-AMKEKGKKLQELFKYCPEEITEEDEAVLE---EMQLTSQRTSHQLNANPLVP---QIPSYEAQNHAKAAHQMAMKLNMKLD-----------STGSVVE---------PSGDIAPSSREEI--PINNLPA--------------------------------NIRYLLTTRDLRTNLSENFDVALTVKGVFMAPKDIKKLEQIGEKPLHLVLESDSPINIRSARNEICRVVKEAM 2764
            GE  ++  +D  EY    E   L +      + K++K+ +V +H K+ Y  +  N Y EVPE++KMT +EV   R  M  ++VKGK CPKPI  W    +SMKILN LK     +PTPIQ+Q IPAIMSG+D+IGIAKTGSGKT+ +LLP+ RH+ +Q  +  GEGPI +++ PTREL++QI +E  K T   ALR V   C+YGG   ++QI+ LKRG EI+V TPGR+ID++A N GR  +  R T++VLDEADRMFDMGFEPQVM II   RPDRQTVMFSATFPR +EA+A++I+ +P+EV+V G + VC+DV QHV +++E+ KF KL+ELL  ++ +G  +VFV+ QE A  L  +L    +    +HGG+ Q  R+  + +FKSG   +++ATS+AARGLDV  L+MVVNYDCPNHYEDYVHR GRTGRAGNKGYSYTF+TS+QE   G++IKAL+ +G  +P +L   +  + E+   EGKT++  SGF G G+KFD  E ++  + KKLQ++     +   EE    ++   E    S++    +NA+        +PS       + A ++A K+N + +           +T S++           +  IA    E+I   +N +PA                                  R+ +T+++    +SE  + A+T++G + AP    K    GE+ ++L +ES S ++++ A+ E+ R++K+ +
Sbjct:  278 GELMEND-QDAMEYSSEEEDSDLATALTGYNQNKQRKMVEVVDHSKIAYEPFRRNFYVEVPELAKMTAEEVSAYRLEMEGVMVKGKGCPKPIKTWVQCGISMKILNTLKKQNYEKPTPIQAQAIPAIMSGRDLIGIAKTGSGKTIGFLLPMFRHVMDQRPLEEGEGPIGVIMTPTRELALQIAKECRKFTKQLALRVV---CVYGGTGISEQIAELKRGAEIIVCTPGRMIDMLAANSGRVTNFRRATYMVLDEADRMFDMGFEPQVMRIIETSRPDRQTVMFSATFPRAMEALARRILNKPVEVQVGGRSVVCSDVEQHVIVIEEDTKFYKLLELLGLYQEKGAVIVFVDKQEHADTLLKDLMKASYPCLSLHGGIDQYDRDSIINDFKSGVCRLMVATSVAARGLDVKHLIMVVNYDCPNHYEDYVHRVGRTGRAGNKGYSYTFITSEQERYSGDIIKALELSGTPLPPDLERLWTEFREKQKAEGKTMRKSSGFSGKGFKFDETEHSLVNERKKLQKVALGMHDSDEEEGSGDIDQQIENMFRSKKIVKDVNAHGASSTGIMMPSGSNAQKLEIAKRLASKINSQRNLGTEAMDVIQQATNSIMRGGTMNVPLVSAKSIAEQLAEKINAKLNYVPAEKLLEEERVEQEKQADKVRRYEEELEINDFPQTARWKVTSKEALAQISEYSEAAITIRGSYFAP---GKEPTDGERKIYLAIESTSELSVQKAKAEVTRLIKDEL 1014
[Close]
BLAST of Pre-mRNA-processing ATP-dependent RNA helicase PRP5 vs. Ensembl Sea Lamprey
Match: ddx42 (DEAD (Asp-Glu-Ala-Asp) box helicase 42 [Source:ZFIN;Acc:ZDB-GENE-050706-53])

HSP 1 Score: 338.576 bits (867), Expect = 1.090e-102
Identity = 203/569 (35.68%), Postives = 313/569 (55.01%), Query Frame = 2 
Query:  629 SDKENTVDTDVDSIDAYMSTL-------IKTVKDPSIAKIGE-FTDDHIEDTD---EYHQTVE--------------PETLESITQALFEEKKQ---KLPDVNHDKVYYRKYDFNLYKEVPEISKMTTKEVKELRRSMAIVVKGKECPKPITKWSHAIVSMKILNALKYNKMNEPTPIQSQTIPAIMSGKDVIGIAKTGSGKTLSYLLPLIRHIHNQPNVTVGEGPIAIVLCPTRELSIQIHQEIEKITYALRDVNCGCIYGGADTAQQISRLKRGVEIVVGTPGRIIDIM---ATNGGRNLSLSRCTFIVLDEADRMFDMGFEPQVMAIISRIRPDRQTVMFSATFPRRIEAVAKKIMKEPIEVRVDGGNKVCTDVVQHVYLLDEND-KFLKLVELLSEFKYRGKSLVFVETQETAQILSSNLTHQGFEVSMIHGGLTQEKREEGMFNFKSGTVPILIATSIAARGLDVNDLMMVVNYDCPNHYEDYVHRCGRTGRAGNKGYSYTFVTSDQEVMIGNLIKALKENGQEIPGELTE-----AYARYTERMVLEGKTIKAPSGFRGHGYK 2224
            S K+   D+D D +DA+M+ +       ++ +++  +AK  +    D IE+ D    Y + +E              P   +S    +  EK +    LP ++H ++ Y  +D N Y E  EIS +   E  EL+      V G   PKP + + H     ++LN ++ ++  +PTPIQ Q IP  +SG+D+IGIAKTGSGKT S++ P++ HI  Q  +  G+GPI ++  PTREL  QI+ E ++   A  +++   +YGG    +Q   L+ G EIVV TPGR+ID +   ATN      L R T++V DEADRMFDMGFE QV +I + +RPDRQT+++SATF  R+E +A+ I+ +PI V      +   DV Q V +      K+  L   L EF   G  L+FV  ++ ++ LS++L  +GF+V ++HG + Q +R + + +FK   +PI++AT +AARGLD+  +  VVNYD     + + HR GRTGRAG KG ++T +T       G+L++ L+   Q +  EL +      + R T      G+ +    G  G GY+
Sbjct:  102 SRKQLNSDSDDDPLDAFMAQVENQAARDMRALEEKEVAKKDDKGVRDDIEEEDGQEAYFRYMEENPTAGLLPVDEEDPMDYDSDGNPIPPEKNKVIDPLPSIDHSEIEYEPFDKNFYVEHEEISSLGASEAHELKAQ----VSGAAPPKPCSSFGHFGFDEQLLNLIRKSEFTQPTPIQCQGIPIALSGRDIIGIAKTGSGKTASFIWPMLVHIMAQKELKPGDGPIGLICVPTRELCQQINVECKRFGKAY-NLHSVAVYGGGSMWEQAKALQEGAEIVVCTPGRLIDHVKKKATN------LQRVTYLVFDEADRMFDMGFEYQVRSIANHVRPDRQTMLYSATFRMRVEKLARDILIDPIRVVQGDIGEANEDVTQRVEIFSNGAAKWNWLCSHLVEFTSSGSVLIFVTRKDNSEELSNDLEQEGFQVGLLHGDMDQSERNKVISDFKKKVIPIMVATDVAARGLDIPSIKTVVNYDVARDIDTHTHRVGRTGRAGEKGTAFTLMTHKDMNFAGDLVRNLEGANQHVHKELMDLAMQNPWFRKTRFKGGRGRKLNVGGG--GLGYR 657
[Close]
BLAST of Pre-mRNA-processing ATP-dependent RNA helicase PRP5 vs. Ensembl Sea Lamprey
Match: ddx23 (DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Source:ZFIN;Acc:ZDB-GENE-030131-6215])

HSP 1 Score: 298.516 bits (763), Expect = 4.085e-88
Identity = 163/428 (38.08%), Postives = 240/428 (56.07%), Query Frame = 2 
Query:  908 EISKMTTKEVKELRRSMAIVVKGKECPKPITKWSHAIVSMKILNALKYNKMNEPTPIQSQTIPAIMSGKDVIGIAKTGSGKTLSYLLPLIRHIHNQPNVT----VGEGPIAIVLCPTRELSIQIHQEIEKITYALRDVNCGCIYGGADTAQQISRLKRGVEIVVGTPGRIIDIMATNGGRNLSLSRCTFIVLDEADRMFDMGFEPQVMAI-----ISRIRPD---------------------RQTVMFSATFPRRIEAVAKKIMKEPIEVRVDGGNKVCTDVVQHVYLLDENDKFLKLVELLSEFKYRGKSLVFVETQETAQILSSNLTHQGFEVSMIHGGLTQEKREEGMFNFKSGTVPILIATSIAARGLDVNDLMMVVNYDCPNHYEDYVHRCGRTGRAGNKGYSYTFVTSDQEVMIGNLIKAL 2101
            ++ +M  ++ +  R    I  KG + P PI  W  +I+   I   ++     +PTPIQ Q IP  +  +D+IGIA+TGSGKT ++L+PL+  I   P +       +GP A++L PTREL+ QI +E  K    L  +    + GG     Q  RL+ G +IV+ TPGR+ID++     R L LSRCT++VLDEADRM DMGFEP V  I     +S  +PD                     RQTVMF+AT P  +E +A+  ++ P  V +    K    V Q V+++ E++K  KL+ELLS   +    ++FV  ++   +L+ +L   GF    +HGG  QE+RE  + N K+G   IL+AT +A RG+D++D+ MV+NYD   + EDY HR GRTGRAG  G S TF+T +   +  +L +A+
Sbjct:  290 KLEEMCERDWRIFREDYNITTKGGKIPNPIRLWKESILPSHIREVIEKCGYKDPTPIQRQAIPIGLQNRDIIGIAETGSGKTAAFLIPLLVWITTLPKIDRIEDTDQGPYAVILAPTRELAQQIEEETIKFGKPL-GIRTVAVIGGISREDQGFRLRMGCKIVIATPGRLIDVLEN---RYLVLSRCTYVVLDEADRMIDMGFEPDVQRILEHMPVSNQKPDTDDAEDPDKMTANFESGRHKYRQTVMFTATMPAAVERLARSYLRRPAVVYIGSVGKPIERVEQRVFIMGESEKRKKLLELLSR-GFEPPIIIFVNQKKGCDVLAKSLEKMGFNACTLHGGKGQEQREFALSNLKAGAKDILVATDVAGRGIDIHDVSMVLNYDMAKNIEDYTHRIGRTGRAGKSGVSVTFLTKEDAAVFYDLKQAM 712
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BLAST of Pre-mRNA-processing ATP-dependent RNA helicase PRP5 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000003898.1 (pep scaffold:Pmarinus_7.0:GL481305:13824:21767:-1 gene:ENSPMAG00000003524.1 transcript:ENSPMAT00000003898.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 291.967 bits (746), Expect = 6.512e-88
Identity = 161/437 (36.84%), Postives = 248/437 (56.75%), Query Frame = 2 
Query:  974 GKECPKPITKWSHAIVSMKILNALKYNKMNEPTPIQSQTIPAIMSGKDVIGIAKTGSGKTLSYLLPLIRHIHN-------------QPNVTVGEG---PIAIVLCPTRELSIQIHQEIEKITYALRDVNCGCIYGGADTAQQISRLKRGVEIVVGTPGRIIDIMATNGGRNLSLSRCTFIVLDEADRMFDMGFEPQVMAIISR----IRPDRQTVMFSATFPRRIEAVAKKIMKEPIEVRVDGGNKVCTDVVQHVYLLDENDKFLKLVELLSEFKYRGKSLVFVETQETAQILSSNLTHQGFEVSMIHGGLTQEKREEGMFNFKSGTVPILIATSIAARGLDVNDLMMVVNYDCPNHYEDYVHRCGRTGRAGNKGYSYTFVTSDQEVMIGNLIKALKENGQEIPGELTEAYARYTERMVLEGKTIKAPSGFRGHGYK 2224
            G +CP  I  +    +   I++++   +   PTP+Q   IP I + +D++  A+TGSGKT ++LLP++  I++             Q  V  G+    P+++VL PTREL++QI+ E  K  Y      C  +YGGAD   Q+  L++G  ++V TPGR++D+M       + L  C ++VLDEADRM DMGFEPQ+  I+ +     + DRQT+MFSATFP+ I+ +A+  +++ I + V        ++ Q V  ++E DK   L++LL+       +LVFVET++ A  L   L  +G+  + IHG  +Q  REE +  F++G  PIL+AT++AARGLD+ ++  V+N+D P+  E+YVHR GRTGR GN G + +F     E M   L+  L E  QE+P  L E  A+        G+  +   GF G  Y+
Sbjct:   51 GNDCPPHIESFHELELGEIIMSSVTLCRYERPTPVQKYAIPIIKAKRDLMACAQTGSGKTAAFLLPILSQIYSGGPGKVVEDTKNQQETVKYGQRKQYPMSLVLAPTRELALQIYDEARKFAYRSCVRPC-VVYGGADIGNQVRELQKGCHLLVATPGRLVDMMERG---KVGLDHCRYLVLDEADRMLDMGFEPQIRRIVEQDVMPTKGDRQTLMFSATFPKEIQILARDFLEDYIFLAVGRVGSASENITQKVVWVEEMDKRSFLLDLLNATGRDSLTLVFVETKKGADALQGFLCSEGYSCTSIHGDRSQRDREEALSLFRTGRRPILVATAVAARGLDIPNVKHVINFDLPSDIEEYVHRIGRTGRVGNLGQATSFYNEKNENMTRELLHLLVEAHQEVPSWL-ETMAQEHRSKPARGRPKRFAGGFGGRDYR 482
[Close]
BLAST of Pre-mRNA-processing ATP-dependent RNA helicase PRP5 vs. Ensembl Sea Lamprey
Match: ddx59 (DEAD (Asp-Glu-Ala-Asp) box polypeptide 59 [Source:ZFIN;Acc:ZDB-GENE-050208-665])

HSP 1 Score: 222.631 bits (566), Expect = 3.501e-63
Identity = 137/447 (30.65%), Postives = 255/447 (57.05%), Query Frame = 2 
Query:  821 EEKKQKLPDVNHDKVYYRKYDFNLYKEVPEISKMTTKEVKELRRSMAIVVKGKECPKPITKWSHAIVSMKILNALKYNKMNEPTPIQSQTIPAIMSGKDVIGIAKTGSGKTLSYLLPLIRHIHNQPNVTVGEGPIAIVLCPTRELSIQIHQEIEKITYALRDVNCGCIYGGADTAQQISRLKRGVEIVVGTPGRIIDIMATNGGRNLSLSRCTFIVLDEADRMFDMGFEPQVMAIISRIRPDRQTVMFSATFPRRIEAVAKKIMKEPIEVRVDG-GNKV------CTDVVQHVYLLDENDKFLKLVELLSEFK-YRGKSLVFVETQETAQILSSNL-THQGFEVSMIHGGLTQEKREEGMFNFKSGTVPILIATSIAARGLDVNDLMMVVNYDCPNHYEDYVHRCGRTGRAGNKGYSYTFVTSDQEVMIGNLIKALKENGQEIPGEL 2134
            E  K +  D +  K  YR      Y+E   IS +T ++V+ LRRS+ I V+G++ P+P+ ++SH  +   +   L     +EPTP+Q Q +P  + G+DVI  A+TGSGKT  +L+P++  +       V + P+A+V+ PTREL++QI ++ +++   L  +    + GG     Q+ RL++ V++V+GTPGR+++++  +    L L+     V+DE D M  +GF  QV+A+      +RQ+++ SAT P     +A+++ ++P+ + V G G++V       ++V Q V  ++E  K  KL E+L + K Y    +VFV+++  A +L+  + T  G + + +H    Q +R   +    +G   ++++T +  RGLD+ ++ +VVN+D P+  ++YVH+ GR+GR G +G + + + +    +  +L   ++  G ++P +L
Sbjct:   85 ENSKNQPRDKSSVKNLYR------YEEHSFISSLTAEQVRSLRRSLGISVEGRDPPRPVLEFSHCPMPEALAQNLAACGYHEPTPVQMQMLPPALGGRDVIVRAETGSGKTAGFLVPIVALLAGCGPSEVRD-PLAVVVTPTRELAMQIERQAKELMAGLPHMRTALLIGGLPLPPQLHRLRQRVQLVIGTPGRVLEVLRRDA---LRLNSVRIFVIDEVDTMLKLGFREQVLAVREETPEERQSLLVSATLPTATVELAERLTRDPVRIAVAGEGSEVGGQAAPASNVRQIVLWVEEPSKKKKLFEILKDEKLYHPPVVVFVDSKMGADLLADAVETVMGLKAAAMHADKPQTERTSVLQGLLAGEYEVVVSTGVLGRGLDLVNVRLVVNFDLPSTMDEYVHQVGRSGRLGRRGTAISLLNNRDRRLFLDLASRVEATGTQLPAQL 521
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BLAST of Pre-mRNA-processing ATP-dependent RNA helicase PRP5 vs. Ensembl Yeast
Match: DBP2 (ATP-dependent RNA helicase of the DEAD-box protein family; has strong preference for dsRNA; interacts with YRA1; required for assembly of Yra1p, Nab2p and Mex67p onto mRNA and formation of nuclear mRNP; involved in mRNA decay and rRNA processing; may be involved in suppression of transcription from cryptic initiation sites [Source:SGD;Acc:S000005056])

HSP 1 Score: 339.347 bits (869), Expect = 1.500e-105
Identity = 174/423 (41.13%), Postives = 256/423 (60.52%), Query Frame = 2 
Query:  878 YDFNLYKEVPEISKMTTKEVKELRRSMAIVVKGKECPKPITKWSHAIVSMKILNALKYNKMNEPTPIQSQTIPAIMSGKDVIGIAKTGSGKTLSYLLPLIRHIHNQPNVTVGEGPIAIVLCPTRELSIQIHQEIEKITYALRDVNCGCIYGGADTAQQISRLKRGVEIVVGTPGRIIDIMATNGGRNLSLSRCTFIVLDEADRMFDMGFEPQVMAIISRIRPDRQTVMFSATFPRRIEAVAKKIMKEPIEVRVD----GGNKVCTDVVQHVYLLDENDKFLKLVELLSEFKYRGKSLVFVETQETAQILSSNLTHQGFEVSMIHGGLTQEKREEGMFNFKSGTVPILIATSIAARGLDVNDLMMVVNYDCPNHYEDYVHRCGRTGRAGNKGYSYTFVTSDQEVMIGNLIKALKENGQEIPGEL 2134
            ++ N Y E   +   +  E+ + R+   + + G + PKPIT +  A     +LN +K    ++PT IQ Q  P  +SG+D++GIA TGSGKTLSY LP I HI+ QP +  G+GPI +VL PTREL++QI  E  K  ++ R  N  C+YGG   +QQI  L RG EIV+ TPGR+ID++        +L R T++VLDEADRM DMGFEPQ+  I+ +IRPDRQT+M+SAT+P+ ++ +A   + +PI+V+V       +   T +V+ V   ++ D+  K +E  S+     K+L+F  T+     ++  L   G+    IHG   Q +R+  +  F++G  PI++AT +AARG+DV  +  V+NYD P + EDYVHR GRTGRAG  G + +F T   + +   LI  ++E  Q IP EL
Sbjct:   73 FEKNFYVEHESVRDRSDSEIAQFRKENEMTISGHDIPKPITTFDEAGFPDYVLNEVKAEGFDKPTGIQCQGWPMALSGRDMVGIAATGSGKTLSYCLPGIVHINAQPLLAPGDGPIVLVLAPTRELAVQIQTECSKFGHSSRIRNT-CVYGGVPKSQQIRDLSRGSEIVIATPGRLIDMLEIG---KTNLKRVTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVKQLAADYLNDPIQVQVGSLELSASHNITQIVEVVSDFEKRDRLNKYLETASQ-DNEYKTLIFASTKRMCDDITKYLREDGWPALAIHGDKDQRERDWVLQEFRNGRSPIMVATDVAARGIDVKGINYVINYDMPGNIEDYVHRIGRTGRAGATGTAISFFTEQNKGLGAKLISIMREANQNIPPEL 490
[Close]
BLAST of Pre-mRNA-processing ATP-dependent RNA helicase PRP5 vs. Ensembl Yeast
Match: PRP5 (RNA helicase in the DEAD-box family; necessary for prespliceosome formation, bridges U1 and U2 snRNPs and enables stable U2 snRNP association with intron RNA [Source:SGD;Acc:S000000441])

HSP 1 Score: 330.872 bits (847), Expect = 4.478e-99
Identity = 227/689 (32.95%), Postives = 361/689 (52.39%), Query Frame = 2 
Query:  860 KVYY-----RKYDFNLYKEVPEISKMTTKEVKELRRSM-AIVVKGKECPKPITKWSHAIVSMK----ILNALKYNKMNEPTPIQSQTIPAIMSGKDVIGIAKTGSGKTLSYLLPLIRHIHNQPNVTVGE-GPIAIVLCPTRELSIQIHQEIEKITYALRDVNCGCIYGGADTAQQISRLKRGVEIVVGTPGRIIDIMATNGGRNLSLSRCTFIVLDEADRMFDMGFEPQVMAIISRIRPDRQTVMFSATFPRRIEAVAKKIMKEPIEVRVDGGNKVCTDVVQHVYLL-DENDKFLKLVELL---SEF----------------KYRGKSLVFVETQETAQILSSNLTHQGFEVSMIHGGLTQEKREEGMFNFKSGTVPILIATSIAARGLDVNDLMMVVNYDCPNHYEDYVHRCGRTGRAGNKGYSYTFVTSDQEVMIGNLIKALKENGQEIPG-------ELTEAYARYTERMVLEGKTIKAPSGFRGHGYKFDAAEAMKEKGKKLQELFKYCPEEITEEDEAVLE-EMQLTSQRTSHQ--LNANPLVPQIPSYEAQNHAKAAHQMAMKLNMKLDSTGSVVEPSGDIAPSSREEIPINNLPANIRYLLTTRDLRTNLSENFDVALTVKGVFMAPKDIKKLEQIGEKPLHLVLESDSPINIRSARNEICRVVKEAMKK*INLSANKMFY 2803
            ++YY       +  N Y E   +S M+  EV+ELR S+  I +KG  CPKP+TKWS   +S      I   L +  +   TPIQSQ +PAIMSG+DVIGI+KTGSGKT+SYLLPL+R +  Q  ++  E GP+ ++L PTREL++QIH+E+ K T A   +   C  GG++  +QI+ LKRG EIVV TPGR IDI+  N G+ LS  R TF+V+DEADR+FD+GFEPQ+  I+  +RPD+Q V+FSATFP ++ + A +++  PI + ++    V  +V Q   +   E++KF  LV+L+   SEF                +   K+++FV +Q     +S  L + G     IH G   ++R   +  FK     IL+ T + +RGL+V ++ +V+ Y+    +  YVH  GRT R    G + T +  D+      L KA+++  +EI         EL E  A++ E  + +GK  +   GF G G +   ++  + + K L         E+ + D+   + E ++++ R  H     ++ L+P++ +YE                 K  + GS++  +         ++ IN+LP  +R+  T       +      ++T KG F  P+  +   +  E  L+L++E     +I+ +   + + VKE + K  +LS     Y
Sbjct:  203 QIYYSPEELEPFQKNFYIESETVSSMSEMEVEELRLSLDNIKIKGTGCPKPVTKWSQLGLSTDTMVLITEKLHFGSL---TPIQSQALPAIMSGRDVIGISKTGSGKTISYLLPLLRQVKAQRPLSKHETGPMGLILAPTRELALQIHEEVTKFTEADTSIRSVCCTGGSEMKKQITDLKRGTEIVVATPGRFIDILTLNDGKLLSTKRITFVVMDEADRLFDLGFEPQITQIMKTVRPDKQCVLFSATFPNKLRSFAVRVLHSPISITINSKGMVNENVKQKFRICHSEDEKFDNLVQLIHERSEFFDEVQSENDGQSSDVEEVDAKAIIFVSSQNICDFISKKLLNAGIVTCAIHAGKPYQERLMNLEKFKREKNSILLCTEVLSRGLNVPEVSLVIIYNAVKTFAQYVHTTGRTARGSRSGTAITLLLHDELSGAYILSKAMRD--EEIKALDPLQAKELQEMSAKF-ESGMKKGK-FRLSKGFGGKGLENIKSKREEAQNKDL---------ELKKNDKRSDDLEKKISNPREGHDSVSESSALIPRL-NYEL---------------FKESTDGSIIFYA---------KVYINDLPQIVRWEATKNTTLLFIKHETGCSITNKGKFY-PEGKEPKNENDEPKLYLLIEGQDEKDIQLSIELLEQKVKEGVVKAASLSLKSTKY 849
[Close]
BLAST of Pre-mRNA-processing ATP-dependent RNA helicase PRP5 vs. Ensembl Yeast
Match: DBP1 (Putative ATP-dependent RNA helicase of the DEAD-box protein family; mutants show reduced stability of the 40S ribosomal subunit scanning through 5' untranslated regions of mRNAs; protein abundance increases in response to DNA replication stress; DBP1 has a paralog, DED1, that arose from the whole genome duplication [Source:SGD;Acc:S000006040])

HSP 1 Score: 285.419 bits (729), Expect = 7.987e-85
Identity = 154/410 (37.56%), Postives = 238/410 (58.05%), Query Frame = 2 
Query:  953 SMAIVVKGKECPKPITKWSHAIVSMKILNALKYNKMNEPTPIQSQTIPAIMSGKDVIGIAKTGSGKTLSYLLPLIRHIHNQPNVTVGEG----------PIAIVLCPTRELSIQIHQEIEKITYALRDVNCGCIYGGADTAQQISRLKRGVEIVVGTPGRIIDIMATNGGRNLSLSRCTFIVLDEADRMFDMGFEPQVMAIISRIR----PDRQTVMFSATFPRRIEAVAKKIMKEPIEVRVDGGNKVCTDVVQHVYLLDENDKFLKLVELLSEFKYRGKSLVFVETQETAQILSSNLTHQGFEVSMIHGGLTQEKREEGMFNFKSGTVPILIATSIAARGLDVNDLMMVVNYDCPNHYEDYVHRCGRTGRAGNKGYSYTFVTSDQEVMIGNLIKALKENGQEIPGELTE 2140
            ++ +   GK+ P+PI  +S   +   ++  +K     +PTP+Q  +IP +  G+D++  A+TGSGKT  +L PL   +       V E           P A+VL PTREL+ QI +E  K TY      C  +YGGA    Q+  + RG +++V TPGR+ D++       +SL+   ++VLDEADRM DMGFEPQ+  I+         +RQT+MFSATFP  I+ +A+  +   I + V        ++ Q +  +D+ DK   L++LLS  +++G +L+FVET+  A  L+  L  Q F+ + IHG  TQ +RE  +  FK+    IL+AT++AARGLD+ ++  V+NYD P+  +DYVHR GRTGRAGN G + +F  S+ + ++  L++ L E  QE+P  L++
Sbjct:  139 NIPVDASGKDVPEPILDFSSPPLDELLMENIKLASFTKPTPVQKYSIPIVTKGRDLMACAQTGSGKTGGFLFPLFTELFRSGPSPVPEKAQSFYSRKGYPSALVLAPTRELATQIFEEARKFTYRSWVRPC-VVYGGAPIGNQMREVDRGCDLLVATPGRLNDLLERG---KVSLANIKYLVLDEADRMLDMGFEPQIRHIVEECDMPSVENRQTLMFSATFPVDIQHLARDFLDNYIFLSVGRVGSTSENITQRILYVDDMDKKSALLDLLSA-EHKGLTLIFVETKRMADQLTDFLIMQNFKATAIHGDRTQAERERALSAFKANVADILVATAVAARGLDIPNVTHVINYDLPSDIDDYVHRIGRTGRAGNTGVATSFFNSNNQNIVKGLMEILNEANQEVPTFLSD 543
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BLAST of Pre-mRNA-processing ATP-dependent RNA helicase PRP5 vs. Ensembl Yeast
Match: DED1 (ATP-dependent DEAD (Asp-Glu-Ala-Asp)-box RNA helicase; required for translation initiation of all yeast mRNAs; binds to mRNA cap-associated factors, and binding stimulates Ded1p RNA-dependent ATPase activity; mutation in human homolog DBY is associated with male infertility; human homolog DDX3X complements ded1 null mutation; DED1 has a paralog, DBP1, that arose from the whole genome duplication [Source:SGD;Acc:S000005730])

HSP 1 Score: 282.722 bits (722), Expect = 4.975e-84
Identity = 153/409 (37.41%), Postives = 238/409 (58.19%), Query Frame = 2 
Query:  968 VKGKECPKPITKWSHAIVSMKILNALKYNKMNEPTPIQSQTIPAIMSGKDVIGIAKTGSGKTLSYLLPLIRHIHN-----QPNVTVGEG--------PIAIVLCPTRELSIQIHQEIEKITYALRDVNCGCIYGGADTAQQISRLKRGVEIVVGTPGRIIDIMATNGGRNLSLSRCTFIVLDEADRMFDMGFEPQVMAII--SRIRP--DRQTVMFSATFPRRIEAVAKKIMKEPIEVRVDGGNKVCTDVVQHVYLLDENDKFLKLVELLSEFKYRGKSLVFVETQETAQILSSNLTHQGFEVSMIHGGLTQEKREEGMFNFKSGTVPILIATSIAARGLDVNDLMMVVNYDCPNHYEDYVHRCGRTGRAGNKGYSYTFVTSDQEVMIGNLIKALKENGQEIPGELTEA 2143
              GK+ P+PIT+++   +   +L  +K  +  +PTP+Q  ++P + +G+D++  A+TGSGKT  +L P++          QP     +G        P A+++ PTREL+ QI  E +K TY      C  +YGG+    Q+  ++RG +++V TPGR+ D++       +SL+   ++VLDEADRM DMGFEPQ+  I+    + P  +RQT+MFSATFP  I+ +A+  + + I + V        ++ Q V  ++  DK   L++LLS     G +L+FVET+  A  L+  L  Q F  + IHG  TQ +RE  +  F+SG   +L+AT++AARGLD+ ++  V+NYD P+  +DYVHR GRTGRAGN G +  F  S+   ++  L + L E  QE+P  L +A
Sbjct:  132 ASGKDVPEPITEFTSPPLDGLLLENIKLARFTKPTPVQKYSVPIVANGRDLMACAQTGSGKTGGFLFPVLSESFKTGPSPQPE---SQGSFYQRKAYPTAVIMAPTRELATQIFDEAKKFTYRSWVKAC-VVYGGSPIGNQLREIERGCDLLVATPGRLNDLLERG---KISLANVKYLVLDEADRMLDMGFEPQIRHIVEDCDMTPVGERQTLMFSATFPADIQHLARDFLSDYIFLSVGRVGSTSENITQKVLYVENQDKKSALLDLLSA-STDGLTLIFVETKRMADQLTDFLIMQNFRATAIHGDRTQSERERALAAFRSGAATLLVATAVAARGLDIPNVTHVINYDLPSDVDDYVHRIGRTGRAGNTGLATAFFNSENSNIVKGLHEILTEANQEVPSFLKDA 532
[Close]
BLAST of Pre-mRNA-processing ATP-dependent RNA helicase PRP5 vs. Ensembl Yeast
Match: DBP3 (RNA-Dependent ATPase, member of DExD/H-box family; involved in cleavage of site A3 within the ITS1 spacer during rRNA processing; not essential for growth, but deletion causes severe slow-growth phenotype [Source:SGD;Acc:S000003046])

HSP 1 Score: 258.07 bits (658), Expect = 6.584e-76
Identity = 139/368 (37.77%), Postives = 221/368 (60.05%), Query Frame = 2 
Query: 1052 NKMNEPTPIQSQTIPAIMSGKDVIGIAKTGSGKTLSYLLPLIRHIHNQPNVTVGEGPIAIVLCPTRELSIQIHQEIEKITYALRDVNCGCIYGGADTAQQISRLKRGVEIVVGTPGRIIDIMATNGGRNLSLSRCTFIVLDEADRMFDMGFEPQVMAIISRIRPD-RQTVMFSATFPRRIEAVAKKIMKEPIEVRVDGGNKVCTD--VVQHVYLLDENDKFLKLVELLSEF----KYRGKSLVFVETQETAQILSSNLTHQGFEVSMIHGGLTQEKREEGMFNFKSGTVPILIATSIAARGLDVNDLMMVVNYDCPNHYEDYVHRCGRTGRAGNKGYSYTFVTSDQEVMIGNLIKALKENGQEIPGEL 2134
            +K  +PTPIQ+   P ++SGKDV+G+A+TGSGKT ++ +P I H+ N        G   +V+ PTREL+ QI+  +  +T  +  + C C+YGG    +Q  +LK+  ++VV TPGR++D++      ++ LS+  ++VLDEADRM + GFE  +  II       RQT+MF+AT+P+ +  +A   M  PI+V +   +++  +  + Q V ++D   K  KL+ELL ++    K   K L+F   ++ A  +  NL + G+ V+ IHG L+Q++R + +  FKSG   +L+AT +AARGLD+ ++  V+N   P   EDYVHR GRTGRAG  G ++T  T  ++ + G L+  L    Q +P +L
Sbjct:  130 SKFPKPTPIQAVAWPYLLSGKDVVGVAETGSGKTFAFGVPAISHLMNDQK---KRGIQVLVISPTRELASQIYDNLIVLTDKV-GMQCCCVYGGVPKDEQRIQLKKS-QVVVATPGRLLDLLQEG---SVDLSQVNYLVLDEADRMLEKGFEEDIKNIIRETDASKRQTLMFTATWPKEVRELASTFMNNPIKVSIGNTDQLTANKRITQIVEVVDPRGKERKLLELLKKYHSGPKKNEKVLIFALYKKEAARVERNLKYNGYNVAAIHGDLSQQQRTQALNEFKSGKSNLLLATDVAARGLDIPNVKTVINLTFPLTVEDYVHRIGRTGRAGQTGTAHTLFTEQEKHLAGGLVNVLNGANQPVPEDL 489
[Close]
BLAST of Pre-mRNA-processing ATP-dependent RNA helicase PRP5 vs. Ensembl Nematostella
Match: EDO42894 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S034])

HSP 1 Score: 539.265 bits (1388), Expect = 4.035e-178
Identity = 298/706 (42.21%), Postives = 434/706 (61.47%), Query Frame = 2 
Query:  824 EKKQKLPDVNHDKVYYRKYDFNLYKEVPEISKMTTKEVKELRRSMA-IVVKGKECPKPITKWSHAIVSMKILNALKYNKMNEPTPIQSQTIPAIMSGKDVIGIAKTGSGKTLSYLLPLIRHIHNQPNVTVGEGPIAIVLCPTRELSIQIHQEIEKITYALRDVNCGCIYGGADTAQQISRLKRGVEIVVGTPGRIIDIMATNGGRNLSLSRCTFIVLDEADRMFDMGFEPQVMAIISRIRPDRQTVMFSATFPRRIEAVAKKIMKEPIEVRVDGGNKVCTDVVQHVYLLDENDKFLKLVELLSEFKYRGKSLVFVETQETAQILSSNLTHQGFEVSMIHGGLTQEKREEGMFNFKSGTVPILIATSIAARGLDVNDLMMVVNYDCPNHYEDYVHRCGRTGRAGNKGYSYTFVTSDQEVMIGNLIKALKENGQEIPGELTEAYARYTERMVLEGKTIKAPSGFRGHGYKFDAAEAMK-EKGKKLQEL---FKYCPEEITEEDEAVLEEMQLTSQRTSHQLNANPLVPQI--PSYEAQNHAKA----AHQMAMKLNMKLDSTGSVVEPSGDIAPS------------------------------------------------SREEIPINNLPANIRYLLTTRDLRTNLSENFDVALTVKGVFMAPKDIKKLEQIGEKPLHLVLESDSPINIRSARNEICRVVKEAM 2764
            +KK++L  V+H  V Y+ +  + Y EVPE++KMT +E  E R S+  I V+GK  PKP+  W+   V +KIL+ LK N   +PTPIQ+Q IP IMSG+D+IGIAKTGSGKTL++L+P+ RHI +QP +   EGPIAIV+ PTREL+IQIH+E +K      ++ C C+YGG   ++QI+ LKRG EI+V TPGR+ID++  N GR  +  RCT++VLDEADRMFDMGFEPQVM II  IRPDRQTVMFSATFPR++EA+A+KI+ +PIE++V G + VC+DV Q+V +++E+DKFLKL+ELL  ++ +G  LVFVE Q++A  L  +L  + +    +HGG+ Q  R+  + +FK+G   ++IATS+AARGLDV  L +VVNYDCPNHYEDYVHR GRTGRAGNKG +YTF+T +Q     ++IKAL+     +P ++      Y E    EGK I   SGF G G+KF+  E  K  + KK+Q+     +   +E   E++A+ + +     +  H      +VPQ+  P+ + +   +A    A  +A K+N K+ +  + ++P+   A                                                    +E+ IN  P   R+ +T+++    ++E  + A+TV+G +  P    K  + GE+ ++L +E  S   I+ A++EI R+VKE +
Sbjct:   78 KKKKELQPVDHKTVVYQPFRKDFYVEVPELAKMTPEETDEFRLSLENIHVRGKNAPKPVKTWAQTGVQLKILDVLKKNSYEKPTPIQAQAIPVIMSGRDMIGIAKTGSGKTLAFLIPMFRHIKDQPPLEREEGPIAIVMTPTRELAIQIHRECKKFCKP-NNLRCVCVYGGTGISEQIAELKRGAEIIVCTPGRMIDMLTANNGRVTNCQRCTYLVLDEADRMFDMGFEPQVMRIIDCIRPDRQTVMFSATFPRQMEALARKILDKPIEIQVGGRSVVCSDVEQNVVVIEEDDKFLKLLELLGLYQEQGSVLVFVEKQDSADSLFKDLLKRSYPCLSLHGGMDQFDRDSTIADFKNGVTKLMIATSVAARGLDVKHLNLVVNYDCPNHYEDYVHRVGRTGRAGNKGTAYTFLTPEQGRFAIDVIKALEMAENPVPEDVRNLANTYIETRKAEGKNIVKNSGFSGKGFKFNDEEKAKVSEAKKIQKWALGLQDSDDEAEAEEKAIDKRLDAVFSKKPH---VKKVVPQVGEPAVKREGEQQAKFNLASSIAAKINQKISAGTNNLDPTQQAASQIIKGGTVTALTGLDLAKQLAQKVHTKLNYEGPQEEVKEKEEEKQEAERYEDEVEINEFPQTARWKITSKETIMTITEYSECAVTVRGTYFPP---GKEPKEGERKIYLYIEGPSERAIQLAKSEIKRIVKEEL 776
[Close]
BLAST of Pre-mRNA-processing ATP-dependent RNA helicase PRP5 vs. Ensembl Nematostella
Match: EDO38061 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SDX5])

HSP 1 Score: 344.739 bits (883), Expect = 1.617e-108
Identity = 175/423 (41.37%), Postives = 264/423 (62.41%), Query Frame = 2 
Query:  872 RKYDFNLYKEVPEISKMTTKEVKELRRSMAIVVKGKECPKPITKWSHAIVSMKILNALKYNKMNEPTPIQSQTIPAIMSGKDVIGIAKTGSGKTLSYLLPLIRHIHNQPNVTVGEGPIAIVLCPTRELSIQIHQEIEKITYALR---DVNCGCIYGGADTAQQISRLKRGVEIVVGTPGRIIDIMATNGGRNLSLSRCTFIVLDEADRMFDMGFEPQVMAIISRIRPDRQTVMFSATFPRRIEAVAKKIMKEPIEVRVDG-GNKVCTDVVQHVYLLDENDKFLKLVELLSEF--KYRGKSLVFVETQETAQILSSNLTHQGFEVSMIHGGLTQEKREEGMFNFKSGTVPILIATSIAARGLDVNDLMMVVNYDCPNHYEDYVHRCGRTGRAGNKGYSYTFVTSDQEVMIGNLIKALKENGQEI 2122
            +K++ N Y+E P +      EV   RRS  + V G+  PKP+T +  +     I +  K     EPT IQ+Q  P  ++G++++GIA+TGSGKTLS++LP I HI++QP +  G+GPI +VLCPTREL+    Q+++++ Y++     +   CIYGGA    QI  L+RGVEI + TPGR+ID++ +   R  +L RCT++VLDEADRM DMGFEPQ+  II +IRPDRQT+M+SAT+P+ ++ +A   + + + + V   G      ++Q V + ++++K  KL++LL E   +   K+L+F ET+  A  L+  L   G+    IHG   Q +R+  +  F+ G  PIL+AT +A+RGLD++D+  V+N+D PN  EDYVHR GRT R+   G SYTF T +       L+  L+E  Q +
Sbjct:   16 QKFEKNFYREHPVVQARGQHEVDAYRRSKDLTVNGRNVPKPVTTFEESAFPDYIQSYFKREGFTEPTMIQAQGWPVALTGRNLVGIAQTGSGKTLSFILPGIVHINHQPLLQPGDGPIVLVLCPTRELA----QQVQEVAYSVGKHCKLRSTCIYGGAPKGPQIRELERGVEICIATPGRLIDMLES---RKTNLRRCTYLVLDEADRMLDMGFEPQIRTIIDQIRPDRQTLMWSATWPKEVQGLAHDFLSDYVHITVGSLGLTANHKILQIVDVCEDHEKEHKLLKLLEEIMGEKENKTLIFTETKRRADELTRKLRSDGWPAMCIHGDKAQPERDWVLSEFRKGHAPILVATDVASRGLDISDIKFVINFDFPNCTEDYVHRIGRTARSDRTGTSYTFFTVNNAKQAKELVSVLQEAKQHV 431
[Close]
BLAST of Pre-mRNA-processing ATP-dependent RNA helicase PRP5 vs. Ensembl Nematostella
Match: EDO43557 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RY08])

HSP 1 Score: 345.125 bits (884), Expect = 1.267e-107
Identity = 170/433 (39.26%), Postives = 270/433 (62.36%), Query Frame = 2 
Query:  839 LPDVNHDKVYYRKYDFNLYKEVPEISKMTTKEVKELRRSMAIVVKGKECPKPITKWSHAIVSMKILNALKYNKMNEPTPIQSQTIPAIMSGKDVIGIAKTGSGKTLSYLLPLIRHIHNQPNVTVGEGPIAIVLCPTRELSIQIHQEIEKITYALRDVNCGCIYGGADTAQQISRLKRGVEIVVGTPGRIIDIMATNGGRNLSLSRCTFIVLDEADRMFDMGFEPQVMAIISRIRPDRQTVMFSATFPRRIEAVAKKIMKEPIEVRVDGGNKVCTDVVQHVYLLDEN-DKFLKLVELLSEFKYRGKSLVFVETQETAQILSSNLTHQGFEVSMIHGGLTQEKREEGMFNFKSGTVPILIATSIAARGLDVNDLMMVVNYDCPNHYEDYVHRCGRTGRAGNKGYSYTFVTSDQEVMIGNLIKALKENGQEIPGEL 2134
            LP V+H ++ Y+ ++ N Y+E PEI+K + +E+ +LR+ M I V G    +P   ++H     +++ +++  +  +PT IQ Q +P  +SG+D+IGIAKTGSGKT ++L P + HI +QP + VG+GPI ++  PTREL  QI+ E  +   A  +++   ++GG +  +Q   L+ G EIVV TPGR+ID +     +  +L R T++V DEADRMFDMGFEPQV +I + +RPDRQT++FSATF +++E + + I+ +P+ V +    +   DV Q V++ +    K+  L + L  F   G  L+FV  +  ++ L++NL    FEV+++HG + Q +R + +  FK   +PIL+AT +AARGLD+  +  V+NYD       + HR GRTGRAG KG +YT +T   +   G+L++ L+   Q +P  L
Sbjct:   53 LPRVDHSEIDYKPFNKNFYEEHPEITKQSKQEIDDLRKKMGIKVSGAMPARPCISFAHFGFDEQMMASIRKLEYTQPTQIQCQALPIALSGRDIIGIAKTGSGKTAAFLWPALVHIMDQPELQVGDGPIVLICAPTRELCQQIYTEARRFGKAY-NIHVVAVFGGGNKYEQSKALQEGAEIVVATPGRLIDHVK---AKATNLHRVTYLVFDEADRMFDMGFEPQVRSIANNVRPDRQTLLFSATFKKKVEHLCRDILVDPVRVVIGELGEANEDVTQIVHIFNSMPSKWEWLTQNLVSFASAGSVLIFVTKKLNSEELATNLRKNDFEVALLHGDMDQFERSKVLGQFKKREIPILVATDVAARGLDIPSIKTVINYDVARDITTHTHRIGRTGRAGEKGNAYTLLTQSDQNFAGDLVRNLEIANQVVPESL 481
[Close]
BLAST of Pre-mRNA-processing ATP-dependent RNA helicase PRP5 vs. Ensembl Nematostella
Match: EDO43602 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RYA5])

HSP 1 Score: 299.671 bits (766), Expect = 5.059e-88
Identity = 169/443 (38.15%), Postives = 248/443 (55.98%), Query Frame = 2 
Query:  818 FEEKKQKLPDVNHDKVYYRKYDFN-LYKEVPEISKMTTKEVKELRRSMAIVVKGKECPKPITKWSHAIVSMKILNALKYNKMNEPTPIQSQTIPAIMSGKDVIGIAKTGSGKTLSYLLPLIRHIHNQPNVT----VGEGPIAIVLCPTRELSIQIHQEIEKITYALRDVNCGCIYGGADTAQQISRLKRGVEIVVGTPGRIIDIMATNGGRNLSLSRCTFIVLDEADRMFDMGFEPQVMAI-----ISRIRPD-------------------RQTVMFSATFPRRIEAVAKKIMKEPIEVRVDGGNKVCTDVVQHVYLLDENDKFLKLVELLSEFKYRGKSLVFVETQETAQILSSNLTHQGFEVSMIHGGLTQEKREEGMFNFKSGTVPILIATSIAARGLDVNDLMMVVNYDCPNHYEDYVHRCGRTGRAGNKGYSYTFVT 2059
             EEK+Q+   +  +K   RK  F+  +     + +MT ++ +  R    I  KG   P PI KW  A +   IL  +      +PTPIQ Q IP  +  +D+IG+A+TGSGKT ++ +PL+  I   P +       +GP A++L PTREL+ QI +EI K    L  +    + GG     Q  +L+ GVEIV+ TPGR+ID++     R L L+RC++IV+DEADRM DMGFEP+V  I     +S ++PD                   RQTVMF+AT P ++E +AK  ++ P  V +    K    V Q VYL++E  K  KL+ELL++       ++FV  ++ A +L+ +L   GF  + +HGG  QE+RE  + + K G+  IL+AT +A RG+D+ D+  V+NYD     EDY HR GRTGRAG  G + +F+T
Sbjct:  289 IEEKEQEGNRLKKEKDKERKVAFDDRHWTKKNLEEMTERDWRIFREDFNISTKGGRIPFPIRKWKEAQIPDSILEIVDKLGYKDPTPIQRQAIPIGLQNRDIIGVAETGSGKTAAFAIPLLVWIMGLPKIERDNDADQGPYALILAPTRELAQQIEEEILKFGRPL-GIRTVSVIGGLSREDQGFQLRLGVEIVIATPGRLIDVLEN---RYLVLNRCSYIVMDEADRMIDMGFEPEVQKILEHLPVSNVKPDSEDSEDPEHLLTHMGKDKYRQTVMFTATMPPQVERLAKNYLRRPAVVYIGSVGKPVERVEQRVYLVNEQQKRKKLLELLNK-DLEPPIIIFVNQKKGADVLAKSLEKMGFRATTLHGGRNQEQREFALSSLKGGSKDILVATDVAGRGIDIKDVSHVINYDMAKTIEDYTHRIGRTGRAGKTGIAVSFLT 726
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BLAST of Pre-mRNA-processing ATP-dependent RNA helicase PRP5 vs. Ensembl Nematostella
Match: EDO39699 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S9G4])

HSP 1 Score: 268.855 bits (686), Expect = 1.483e-80
Identity = 165/418 (39.47%), Postives = 235/418 (56.22%), Query Frame = 2 
Query:  968 VKGKECPKPITKWSHAIVSM-KILNALKYNKMNEPTPIQSQTIPAIMSGKDVIGIAKTGSGKTLSYLLPLIRHIHNQPNVTVGEG-PIAIVLCPTRELSIQIHQEIEKITYALRDVNCGCIYGGADTAQQISRLKRGVEIVVGTPGRIIDIMATNGGRNLSLSRCTF-----------IVLDEADRMFDMGFEPQVMAIISRIRPDRQTVMFSATFPRRIEAVAKKIMKEPIEVRVDGGN-KVCTDVVQHVYLLDENDKFLKLVELLSEFKYRGKSLVFVETQETAQILSSNLTHQGFE-VSMIHGGLTQEKREEGMFNFKSGTVPILIATSIAARGLDVNDLMMVVNYDCPNHYEDYVHRCGRTGR-------AGNKGYSYTFVTSDQEVMIGNLIKALKENGQEIPGELTEAYARY 2155
            V+ +  P P+TK+  A     +IL  +K     +P+PIQ Q  P +MSG D+IGIA+TG+GKTL++LLP   HI  Q       G P  +VL PTREL++QI QE++K  Y  R +   CIYGG     QI  +++GVEIV+ TPGR+ D++  +    LS+   T+           IVLDEADRM DMGFEP++  I+  IRPDRQTVM SAT+P  ++ +A + M +P+ V V   +   C +V Q V  +D + K  +++E +       K L+FV  +  A  LSS+L   G + V  IHG   Q  RE+ + +FK+G   ILIAT +A+RGLD+ D+  V+NYD P H E+    C  T         +   G S TF++ +       LIK + +  QE+P  L +   RY
Sbjct:   13 VQERAIPNPVTKFEEAFEQYPEILEEIKKAGFVKPSPIQCQAWPVVMSGMDLIGIAQTGTGKTLAFLLPAFLHIDGQELAREKRGGPSVLVLSPTRELALQIEQEVKK--YHYRGIRSVCIYGGGSRKDQIGVVEKGVEIVIATPGRLNDLLMHD---ILSVRSVTYLVSMSGHNICSIVLDEADRMLDMGFEPEIKKILLDIRPDRQTVMTSATWPPGVQRMADQYMTDPVRVFVGCLDLNACENVTQLVEEVDGSLKKERVIEFIEGMAPGEKVLIFVGKKVLADDLSSDLMLHGIDGVQCIHGDREQYDREQALDDFKTGLARILIATDVASRGLDIKDITYVINYDFPRHIEEGGGGCYLTQTLSLSFCFSSRSGTSLTFISREDWRSAHKLIKIMVQANQEVPDFLHDMAKRY 425
[Close]
BLAST of Pre-mRNA-processing ATP-dependent RNA helicase PRP5 vs. Ensembl Medaka
Match: ddx46 (DEAD-box helicase 46 [Source:NCBI gene;Acc:101161571])

HSP 1 Score: 551.592 bits (1420), Expect = 2.243e-180
Identity = 278/582 (47.77%), Postives = 389/582 (66.84%), Query Frame = 2 
Query:  623 KESDKENTVDTD-VDSIDAYMSTLIKTVKDPSIA------------------------------KIGEFTDDHIEDTDEYHQTVEPETLESITQALFEEKKQKLPDVNHDKVYYRKYDFNLYKEVPEISKMTTKEVKELRRSM-AIVVKGKECPKPITKWSHAIVSMKILNALKYNKMNEPTPIQSQTIPAIMSGKDVIGIAKTGSGKTLSYLLPLIRHIHNQPNVTVGEGPIAIVLCPTRELSIQIHQEIEKITYALRDVNCGCIYGGADTAQQISRLKRGVEIVVGTPGRIIDIMATNGGRNLSLSRCTFIVLDEADRMFDMGFEPQVMAIISRIRPDRQTVMFSATFPRRIEAVAKKIMKEPIEVRVDGGNKVCTDVVQHVYLLDENDKFLKLVELLSEFKYRGKSLVFVETQETAQILSSNLTHQGFEVSMIHGGLTQEKREEGMFNFKSGTVPILIATSIAARGLDVNDLMMVVNYDCPNHYEDYVHRCGRTGRAGNKGYSYTFVTSDQEVMIGNLIKALKENGQEIPGELTEAYARYTERMVLEGKTIKAPSGFRGHGYKFDAAE-AMKEKGKKLQ 2269
            KE+  E   + D VD +DAYM  + + VK  +++                              K GE  ++  +D  EY    E   L++       ++++ L  V+H K+ Y  Y  N Y EVPE++KMTT+EV   R  +  I+VKGK CPKPI  W    VSMKIL+ALK    ++PTPIQ+Q IPAIMSG+D+IGIAKTGSGKT+++LLP+ RHI +Q  +   EGPI++++ PTREL++QI +E +K + AL  +   C+YGG   ++QI+ LKRG EI+V TPGR+ID++  N GR  +L R T++VLDEADRMFDMGFEPQVM I+  +RPDRQTVMFSATFPR +EA+A++I+ +PIEV+V G + VC+DV QHV +++E+ KFLKL+E+L  ++ +G  ++FV+ QE A  L  +L    +    +HGG+ Q  R+  + +FK+G   +++ATS+AARGLDV  L++VVNY+CPNHYEDYVHR GRTGRAGNKGY+YTF+T DQ    G++IK L+ +G  +P EL + +A + ++   EGKTIK+ SGF G G+KFD  E A+  + KKLQ
Sbjct:  121 KETPMEQQAEEDEVDPLDAYMEEVKQEVKKFNMSDMKGNDKKGAMMVTKVVTVVKTKKGAGTHKKKGELMEND-QDAMEYSSEEEEVDLQTALTGFQTKQRKILEPVDHAKIQYEPYRKNFYVEVPELAKMTTEEVNAYRLELEGIMVKGKGCPKPIKTWVQCGVSMKILSALKKQGYDKPTPIQAQAIPAIMSGRDLIGIAKTGSGKTIAFLLPMFRHIMDQRPLEESEGPISVIMTPTRELALQITKECKKFSKAL-GLRVVCVYGGTGISEQIAELKRGAEIIVCTPGRMIDMLGANSGRVTNLRRATYVVLDEADRMFDMGFEPQVMRIVDNVRPDRQTVMFSATFPRAMEALARRILSKPIEVQVGGRSVVCSDVEQHVLVIEEDQKFLKLLEILGHYQEKGSVIIFVDKQEHADGLLKDLMKASYPCLSLHGGIDQYDRDSIINDFKNGVCRLMVATSVAARGLDVKQLILVVNYNCPNHYEDYVHRAGRTGRAGNKGYAYTFITEDQVRYAGDIIKGLELSGAPVPPELEQLWASFKDQQKAEGKTIKSSSGFSGKGFKFDETEHALANERKKLQ 700

HSP 2 Score: 60.4622 bits (145), Expect = 9.211e-9
Identity = 46/156 (29.49%), Postives = 81/156 (51.92%), Query Frame = 2 
Query: 2324 EEMQLTSQRTSHQLNANPLVPQIPSYEAQNHAKAAHQMAMKLNMKLDSTGSVVEP------SGDIAPSSR---EEIPINNLPANIRYLLTTRDLRTNLSENFDVALTVKGVFMAPKDIKKLEQIGEKPLHLVLESDSPINIRSARNEICRVVKEAM 2764
            E   +  Q T+  L   P+V   PS  A+     A Q+A K+N KL+ T   VE       S + A + R   EE+ IN+ P   R+ +T+++    + E  + A+T++G +  P    K  + GE+ ++L +ES + + ++ A+ EI R++KE +
Sbjct:  790 EAQDVMQQATNAILRGGPIVS--PSVSAKT---IAEQLAEKINAKLNYT--PVEKLEEERQSAEQAETVRRYEEELEINDFPQTARWKVTSKEALQRIGEYSEAAITIRGTYFPPG---KEPKEGERKIYLAIESANELAVQKAKTEITRLIKEEL 935
[Close]
BLAST of Pre-mRNA-processing ATP-dependent RNA helicase PRP5 vs. Ensembl Medaka
Match: ddx46 (DEAD-box helicase 46 [Source:NCBI gene;Acc:101161571])

HSP 1 Score: 552.362 bits (1422), Expect = 2.721e-179
Identity = 278/582 (47.77%), Postives = 389/582 (66.84%), Query Frame = 2 
Query:  623 KESDKENTVDTD-VDSIDAYMSTLIKTVKDPSIA------------------------------KIGEFTDDHIEDTDEYHQTVEPETLESITQALFEEKKQKLPDVNHDKVYYRKYDFNLYKEVPEISKMTTKEVKELRRSM-AIVVKGKECPKPITKWSHAIVSMKILNALKYNKMNEPTPIQSQTIPAIMSGKDVIGIAKTGSGKTLSYLLPLIRHIHNQPNVTVGEGPIAIVLCPTRELSIQIHQEIEKITYALRDVNCGCIYGGADTAQQISRLKRGVEIVVGTPGRIIDIMATNGGRNLSLSRCTFIVLDEADRMFDMGFEPQVMAIISRIRPDRQTVMFSATFPRRIEAVAKKIMKEPIEVRVDGGNKVCTDVVQHVYLLDENDKFLKLVELLSEFKYRGKSLVFVETQETAQILSSNLTHQGFEVSMIHGGLTQEKREEGMFNFKSGTVPILIATSIAARGLDVNDLMMVVNYDCPNHYEDYVHRCGRTGRAGNKGYSYTFVTSDQEVMIGNLIKALKENGQEIPGELTEAYARYTERMVLEGKTIKAPSGFRGHGYKFDAAE-AMKEKGKKLQ 2269
            KE+  E   + D VD +DAYM  + + VK  +++                              K GE  ++  +D  EY    E   L++       ++++ L  V+H K+ Y  Y  N Y EVPE++KMTT+EV   R  +  I+VKGK CPKPI  W    VSMKIL+ALK    ++PTPIQ+Q IPAIMSG+D+IGIAKTGSGKT+++LLP+ RHI +Q  +   EGPI++++ PTREL++QI +E +K + AL  +   C+YGG   ++QI+ LKRG EI+V TPGR+ID++  N GR  +L R T++VLDEADRMFDMGFEPQVM I+  +RPDRQTVMFSATFPR +EA+A++I+ +PIEV+V G + VC+DV QHV +++E+ KFLKL+E+L  ++ +G  ++FV+ QE A  L  +L    +    +HGG+ Q  R+  + +FK+G   +++ATS+AARGLDV  L++VVNY+CPNHYEDYVHR GRTGRAGNKGY+YTF+T DQ    G++IK L+ +G  +P EL + +A + ++   EGKTIK+ SGF G G+KFD  E A+  + KKLQ
Sbjct:  231 KETPMEQQAEEDEVDPLDAYMEEVKQEVKKFNMSDMKGNDKKGAMMVTKVVTVVKTKKGAGTHKKKGELMEND-QDAMEYSSEEEEVDLQTALTGFQTKQRKILEPVDHAKIQYEPYRKNFYVEVPELAKMTTEEVNAYRLELEGIMVKGKGCPKPIKTWVQCGVSMKILSALKKQGYDKPTPIQAQAIPAIMSGRDLIGIAKTGSGKTIAFLLPMFRHIMDQRPLEESEGPISVIMTPTRELALQITKECKKFSKAL-GLRVVCVYGGTGISEQIAELKRGAEIIVCTPGRMIDMLGANSGRVTNLRRATYVVLDEADRMFDMGFEPQVMRIVDNVRPDRQTVMFSATFPRAMEALARRILSKPIEVQVGGRSVVCSDVEQHVLVIEEDQKFLKLLEILGHYQEKGSVIIFVDKQEHADGLLKDLMKASYPCLSLHGGIDQYDRDSIINDFKNGVCRLMVATSVAARGLDVKQLILVVNYNCPNHYEDYVHRAGRTGRAGNKGYAYTFITEDQVRYAGDIIKGLELSGAPVPPELEQLWASFKDQQKAEGKTIKSSSGFSGKGFKFDETEHALANERKKLQ 810

HSP 2 Score: 60.077 bits (144), Expect = 1.159e-8
Identity = 46/156 (29.49%), Postives = 81/156 (51.92%), Query Frame = 2 
Query: 2324 EEMQLTSQRTSHQLNANPLVPQIPSYEAQNHAKAAHQMAMKLNMKLDSTGSVVEP------SGDIAPSSR---EEIPINNLPANIRYLLTTRDLRTNLSENFDVALTVKGVFMAPKDIKKLEQIGEKPLHLVLESDSPINIRSARNEICRVVKEAM 2764
            E   +  Q T+  L   P+V   PS  A+     A Q+A K+N KL+ T   VE       S + A + R   EE+ IN+ P   R+ +T+++    + E  + A+T++G +  P    K  + GE+ ++L +ES + + ++ A+ EI R++KE +
Sbjct:  900 EAQDVMQQATNAILRGGPIVS--PSVSAKT---IAEQLAEKINAKLNYT--PVEKLEEERQSAEQAETVRRYEEELEINDFPQTARWKVTSKEALQRIGEYSEAAITIRGTYFPPG---KEPKEGERKIYLAIESANELAVQKAKTEITRLIKEEL 1045
[Close]
BLAST of Pre-mRNA-processing ATP-dependent RNA helicase PRP5 vs. Ensembl Medaka
Match: ddx5 (probable ATP-dependent RNA helicase DDX5 [Source:NCBI gene;Acc:101160075])

HSP 1 Score: 370.933 bits (951), Expect = 1.276e-115
Identity = 186/426 (43.66%), Postives = 275/426 (64.55%), Query Frame = 2 
Query:  875 KYDFNLYKEVPEISKMTTKEVKELRRSMAIVVKGKECPKPITKWSHAIVSMKILNALKYNKMNEPTPIQSQTIPAIMSGKDVIGIAKTGSGKTLSYLLPLIRHIHNQPNVTVGEGPIAIVLCPTRELSIQIHQEIEKITYALRDVNCGCIYGGADTAQQISRLKRGVEIVVGTPGRIIDIMATNGGRNLSLSRCTFIVLDEADRMFDMGFEPQVMAIISRIRPDRQTVMFSATFPRRIEAVAKKIMKEPIEVRVDGGNKVCT--DVVQHVYLLDENDKFLKLVELLSEF--KYRGKSLVFVETQETAQILSSNLTHQGFEVSMIHGGLTQEKREEGMFNFKSGTVPILIATSIAARGLDVNDLMMVVNYDCPNHYEDYVHRCGRTGRAGNKGYSYTFVTSDQEVMIGNLIKALKENGQEIPGELTE 2140
            K++ N Y++  ++++ + +EV++ RR+  I VKG+ECP PIT +  A     ++  +      EPTPIQ+Q  P  +SGKD++GIA+TGSGKTLSYLLP I HI++QP +  G+GPI +VL PTREL+ Q+ Q   +   A R +   CIYGGA    QI  L+RGVEI + TPGR+ID + +      +L RCT++VLDEADRM DMGFEPQ+  I+ +IRPDRQT+M+SAT+P+ +  +A+  +KE +++ V G  ++    +++Q V +  + +K  KLV LL E   +   K+++FVET+     L+  +   G+    IHG  +Q++R+  +  FK G  PILIAT +A+RGLDV D+  V+NYD PN+ EDY+HR GRT R+   G +YTF T++      +LI  L+E  Q I  +L +
Sbjct:   61 KFEKNFYQQHADVARRSPQEVEQYRRTKVITVKGRECPNPITHFHEASFPSYVMEVINKQNWTEPTPIQAQGWPLALSGKDMVGIAQTGSGKTLSYLLPAIVHINHQPFLERGDGPICLVLAPTRELAQQVQQVAAEYGRASR-LKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLESG---KTNLRRCTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAEDFLKEYVQINV-GALQLSANHNILQIVDVCTDGEKENKLVRLLEEIMSEKENKTIIFVETKRRCDDLTRRMRRDGWPAMGIHGDKSQQERDWVLNEFKFGKAPILIATDVASRGLDVEDVKFVINYDYPNNSEDYIHRIGRTARSSKTGTAYTFFTANNMRQASDLIAVLREANQAINPKLLQ 481
[Close]
BLAST of Pre-mRNA-processing ATP-dependent RNA helicase PRP5 vs. Ensembl Medaka
Match: DDX5 (probable ATP-dependent RNA helicase DDX5 [Source:NCBI gene;Acc:101167926])

HSP 1 Score: 367.081 bits (941), Expect = 4.759e-114
Identity = 183/426 (42.96%), Postives = 276/426 (64.79%), Query Frame = 2 
Query:  875 KYDFNLYKEVPEISKMTTKEVKELRRSMAIVVKGKECPKPITKWSHAIVSMKILNALKYNKMNEPTPIQSQTIPAIMSGKDVIGIAKTGSGKTLSYLLPLIRHIHNQPNVTVGEGPIAIVLCPTRELSIQIHQEIEKITYALRDVNCGCIYGGADTAQQISRLKRGVEIVVGTPGRIIDIMATNGGRNLSLSRCTFIVLDEADRMFDMGFEPQVMAIISRIRPDRQTVMFSATFPRRIEAVAKKIMKEPIEVRVDGGNKVCT--DVVQHVYLLDENDKFLKLVELLSEF--KYRGKSLVFVETQETAQILSSNLTHQGFEVSMIHGGLTQEKREEGMFNFKSGTVPILIATSIAARGLDVNDLMMVVNYDCPNHYEDYVHRCGRTGRAGNKGYSYTFVTSDQEVMIGNLIKALKENGQEIPGELTE 2140
            K+  N Y+E P+++  + +E+++ RRS  + VKG++CPKP+ K++ A     +++ +      +PTPIQSQ  P  +SGKD++GIA+TGSGKTL+YLLP I HI +QP +  G+GPI +VL PTREL+ Q+ Q   +   A R +   CIYGGA    QI  L+RGVEI + TPGR+ID +  N     +L RCT++VLDEADRM DMGFEPQ+  I+ +IRPDRQT+M+SAT+P+ +  +A+  +K+ +++ + G  ++    +++Q V + ++ +K  KL+ LL E   +   K+++FVET+     L+  +   G+    IHG  +Q++R+  +  F+ G  PILIAT +A+RGLDV D+  V+NYD PN  EDY+HR GRT R+   G +YTF T +     G+LI  L+E  Q I  +L +
Sbjct:   59 KFQKNFYQEHPDVTHRSPQEIEQYRRSKEVTVKGRDCPKPMIKFNEASFPSYVMDMIVKQNFTDPTPIQSQGWPVALSGKDMVGIAQTGSGKTLAYLLPAIVHIQHQPFLEHGDGPICLVLAPTRELAQQVQQVAAEYGRASR-LKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLECN---KTNLRRCTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAEDFLKDYVQINI-GALQLSANHNILQIVDVCNDMEKEDKLIRLLEEIMSEKENKTIIFVETKRRCDELTRRMRRDGWPAMGIHGDKSQQERDWVLNEFRYGKAPILIATDVASRGLDVEDVKFVINYDYPNSSEDYIHRIGRTARSQKTGTAYTFFTPNNMKQAGDLISVLREANQAINPKLIQ 479
[Close]
BLAST of Pre-mRNA-processing ATP-dependent RNA helicase PRP5 vs. Ensembl Medaka
Match: si:dkey-156n14.5 (probable ATP-dependent RNA helicase DDX17 [Source:NCBI gene;Acc:101158507])

HSP 1 Score: 363.614 bits (932), Expect = 1.549e-112
Identity = 185/426 (43.43%), Postives = 272/426 (63.85%), Query Frame = 2 
Query:  875 KYDFNLYKEVPEISKMTTKEVKELRRSMAIVVKGKECPKPITKWSHAIVSMKILNALKYNKMNEPTPIQSQTIPAIMSGKDVIGIAKTGSGKTLSYLLPLIRHIHNQPNVTVGEGPIAIVLCPTRELSIQIHQEIEKITYALRDVNCGCIYGGADTAQQISRLKRGVEIVVGTPGRIIDIMATNGGRNLSLSRCTFIVLDEADRMFDMGFEPQVMAIISRIRPDRQTVMFSATFPRRIEAVAKKIMKEPIEVRVDGGNKVCT--DVVQHVYLLDENDKFLKLVELLSEF--KYRGKSLVFVETQETAQILSSNLTHQGFEVSMIHGGLTQEKREEGMFNFKSGTVPILIATSIAARGLDVNDLMMVVNYDCPNHYEDYVHRCGRTGRAGNKGYSYTFVTSDQEVMIGNLIKALKENGQEIPGELTE 2140
            K++ N Y E PE+  ++  EV+E RR   I ++G  CPKP+T +  A     +++ L      EPT IQSQ  P  +SGKD++GIA+TGSGKTL+YLLP I HI++QP +  G+GPI +VL PTREL+ Q+ Q       + R +   C+YGGA    QI  L+RGVEI + TPGR+ID +        +L RCT++VLDEADRM DMGFEPQ+  I+ +IRPDRQT+M+SAT+P+ +  +A+  ++E I++ + G  ++    +++Q V +  EN+K  KL++L+ E   +   K+++FVET++    L+  +   G+    IHG  +Q +R+  +  F+SG  PILIAT +A+RGLDV D+  V+NYD P+  EDYVHR GRT R+ NKG +YTF T        +L++ L+E  Q I  +L +
Sbjct:   55 KFEKNFYIEHPEVQHVSQFEVEEFRRKKEITIRGSGCPKPVTAFHQAHFPQYVMDVLMQQNFKEPTAIQSQGFPVALSGKDMVGIAQTGSGKTLAYLLPAIVHINHQPYLERGDGPICLVLAPTRELAQQVQQVAYDYGKSSR-IKSTCVYGGAPKGPQIRDLERGVEICIATPGRLIDFLEAG---KTNLRRCTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAEDFLREYIQINI-GALELSANHNILQIVDVCMENEKDNKLLQLMEEIMAEKENKTIIFVETKKRCDDLTRKMRRDGWPAMCIHGDKSQPERDWVLTEFRSGKAPILIATDVASRGLDVEDVKFVINYDYPSSSEDYVHRIGRTARSTNKGTAYTFFTPGNLRQARDLVRVLEEARQAINPKLLQ 475
[Close]
BLAST of Pre-mRNA-processing ATP-dependent RNA helicase PRP5 vs. Planmine SMEST
Match: SMESG000075674.1 (SMESG000075674.1)

HSP 1 Score: 1571.6 bits (4068), Expect = 0.000e+0
Identity = 754/755 (99.87%), Postives = 754/755 (99.87%), Query Frame = 2 
Query:  506 DNKKELAEDVAAEDPPALDYDSDDFVEMLPKSTSVIPVVKESDKENTVDTDVDSIDAYMSTLIKTVKDPSIAKIGEFTDDHIEDTDEYHQTVEPETLESITQALFEEKKQKLPDVNHDKVYYRKYDFNLYKEVPEISKMTTKEVKELRRSMAIVVKGKECPKPITKWSHAIVSMKILNALKYNKMNEPTPIQSQTIPAIMSGKDVIGIAKTGSGKTLSYLLPLIRHIHNQPNVTVGEGPIAIVLCPTRELSIQIHQEIEKITYALRDVNCGCIYGGADTAQQISRLKRGVEIVVGTPGRIIDIMATNGGRNLSLSRCTFIVLDEADRMFDMGFEPQVMAIISRIRPDRQTVMFSATFPRRIEAVAKKIMKEPIEVRVDGGNKVCTDVVQHVYLLDENDKFLKLVELLSEFKYRGKSLVFVETQETAQILSSNLTHQGFEVSMIHGGLTQEKREEGMFNFKSGTVPILIATSIAARGLDVNDLMMVVNYDCPNHYEDYVHRCGRTGRAGNKGYSYTFVTSDQEVMIGNLIKALKENGQEIPGELTEAYARYTERMVLEGKTIKAPSGFRGHGYKFDAAEAMKEKGKKLQELFKYCPEEITEEDEAVLEEMQLTSQRTSHQLNANPLVPQIPSYEAQNHAKAAHQMAMKLNMKLDSTGSVVEPSGDIAPSSREEIPINNLPANIRYLLTTRDLRTNLSENFDVALTVKGVFMAPKDIKKLEQIGEKPLHLVLESDSPINIRSARNEICRVVKEAMKK 2770
            DNKKELAEDVAAEDPPALDYDSDDFVEMLPKSTSVIPVVKESDKENTVDTDVDSIDAYMSTLIKTVKDPSIAKIGEFTDDHIEDTDEYHQTVEPETLESITQALFEEKKQKLPDVNHDKVYYRKYDFNLYKEVPEISKMTTKEVKELRRSMAIVVKGKECPKPITKWSHAIVSMKILNALKYNKMNEPTPIQSQTIPAIMSGKDVIGIAKTGSGKTLSYLLPLIRHIHNQPNVTVGEGPIAIVLCPTRELSIQIHQEIEKITYALRDVNCGCIYGGADTAQQISRLKRGVEIVVGTPGRIIDIMATNGGRNLSLSRCTFIVLDEADRMFDMGFEPQVMAIISRIRPDRQTVMFSATFPRRIEAVAKKIMKEPIEVRVDGGNKVCTDVVQHVYLLDENDKFLKLVELLSEFKYRGKSLVFVETQETAQILSSNLTHQGFEVSMIHGGLTQEKREEGMFNFKSGTVPILIATSIAARGLDVNDLMMVVNYDCPNHYEDYVHRCGRTGRAGNKGYSYTFVTSDQEVMIGNLIKALKENGQEIPGELTEAYARYTERMV EGKTIKAPSGFRGHGYKFDAAEAMKEKGKKLQELFKYCPEEITEEDEAVLEEMQLTSQRTSHQLNANPLVPQIPSYEAQNHAKAAHQMAMKLNMKLDSTGSVVEPSGDIAPSSREEIPINNLPANIRYLLTTRDLRTNLSENFDVALTVKGVFMAPKDIKKLEQIGEKPLHLVLESDSPINIRSARNEICRVVKEAMKK
Sbjct:  117 DNKKELAEDVAAEDPPALDYDSDDFVEMLPKSTSVIPVVKESDKENTVDTDVDSIDAYMSTLIKTVKDPSIAKIGEFTDDHIEDTDEYHQTVEPETLESITQALFEEKKQKLPDVNHDKVYYRKYDFNLYKEVPEISKMTTKEVKELRRSMAIVVKGKECPKPITKWSHAIVSMKILNALKYNKMNEPTPIQSQTIPAIMSGKDVIGIAKTGSGKTLSYLLPLIRHIHNQPNVTVGEGPIAIVLCPTRELSIQIHQEIEKITYALRDVNCGCIYGGADTAQQISRLKRGVEIVVGTPGRIIDIMATNGGRNLSLSRCTFIVLDEADRMFDMGFEPQVMAIISRIRPDRQTVMFSATFPRRIEAVAKKIMKEPIEVRVDGGNKVCTDVVQHVYLLDENDKFLKLVELLSEFKYRGKSLVFVETQETAQILSSNLTHQGFEVSMIHGGLTQEKREEGMFNFKSGTVPILIATSIAARGLDVNDLMMVVNYDCPNHYEDYVHRCGRTGRAGNKGYSYTFVTSDQEVMIGNLIKALKENGQEIPGELTEAYARYTERMVSEGKTIKAPSGFRGHGYKFDAAEAMKEKGKKLQELFKYCPEEITEEDEAVLEEMQLTSQRTSHQLNANPLVPQIPSYEAQNHAKAAHQMAMKLNMKLDSTGSVVEPSGDIAPSSREEIPINNLPANIRYLLTTRDLRTNLSENFDVALTVKGVFMAPKDIKKLEQIGEKPLHLVLESDSPINIRSARNEICRVVKEAMKK 871
[Close]
BLAST of Pre-mRNA-processing ATP-dependent RNA helicase PRP5 vs. Planmine SMEST
Match: SMESG000079612.1 (SMESG000079612.1)

HSP 1 Score: 649.432 bits (1674), Expect = 0.000e+0
Identity = 363/789 (46.01%), Postives = 495/789 (62.74%), Query Frame = 2 
Query:  683 STLIKTVKDPSIAKIGEFTDDHIEDTDEYHQTVEPETLESITQALFEEKKQKLPDVNHDKVYYRKYDFNLYKEVPEISKMTTKEVKELRRSMA-IVVKGKECPKPITKWSHAIVSMKILNALKYNKMNEPTPIQSQTIPAIMSGKDVIGIAKTGSGKTLSYLLPLIRHIHNQPNVTVGEGPIAIVLCPTRELSIQIHQEIEKITYALRDVNCGCIYGGADTAQQISRLKRGVEIVVGTPGRIIDIMATNGGRNLSLSRCTFIVLDEADRMFDMGFEPQVMAIISRIRPDRQTVMFSATFPRRIEAVAKKIMKEPIEVRVDGGNKVCTDVVQHVYLLDENDKFLKLVELLSEFKYRGKSLVFVETQETAQILSSNLTHQGFEVSMIHGGLTQEKREEGMFNFKSGTVPILIATSIAARGLDVNDLMMVVNYDCPNHYEDYVHRCGRTGRAGNKGYSYTFVTSDQEVMIGNLIKALKENGQEIPGELTEAYARYTERMVLEGKTIKAPSGFRGHGYKFDAAEAMKEKGKKLQELFKYCPEEITEE---DEAVLEEMQLTSQRTSHQLNANPLVPQIPSYE--AQNHA--------KAAHQMAMKLNMKL-------DST---------GSVVEPSG------------DIAPSSREEI------------------------------PINNLPANIRYLLTTRDLRTNLSENFDVALTVKGVFMAPKDIK-KLEQIGEKPLHLVLESDSPINIRSARNEICRVVKEAMKK*INLSANKMFY*IIMMRFSV 2830
            S +IKTV   S  + GE  +D+I+  +   +  E         A    KK KLP V+H+K+YY+K   N Y EV E+ KMT  EV + R S+  I VKGK+CPKPI  W+H  VS KI+  LK +K   PTPIQ Q IPAIMSG+DVIG+AKTGSGKT++YL+PL+RH+  QP V  GEGPI+IV+ PTREL+ QI++EI K+T   +++ C CIYGG   ++QI++LK G EI+V TPGR+ID+MA NGGR  ++ RCTF+VLDEADRMFDMGFEPQV+ I+  IRPDRQTVMFSATFPR++EA+A+K++  PIE+ V G + VC DV Q+  +LDE +KF KL+ELL  ++  GK +VFVE QE A  L   L  +G+  + +HGG+ Q+ R+  + NFK+G  P+LIATS+AARGLDV DL +VVNYDCPNHYEDYVHRCGRTGRAGNKG +YTFVT DQE  IG++IKA K +G   P +L  AY ++ ERM  EGK + + SGF+G G++FD AE+     ++  E      E+  EE   D+ +++      +R    ++ N +V   PS    A + A        +AA Q AMK++++        D T         G V+  +G            D+A    EEI                               IN+  +N+RY LT+++  TNLSE +DV ++V+G++M P  IK K+EQ GE+PL+L LES S I I++A+ EI R++KE +     L   K+ + ++  R+ V
Sbjct:  188 SQIIKTVVKKSKTEKGEIMEDNIDAIEYSTEEEEETLESMSVIA----KKDKLPVVDHNKIYYQKVHTNFYIEVDELKKMTPNEVSKYRNSLGGIKVKGKDCPKPIKTWAHCGVSSKIMTILKMHKFLNPTPIQCQAIPAIMSGRDVIGVAKTGSGKTMAYLIPLMRHVKAQPPVQSGEGPISIVMSPTRELACQIYREILKLTNG-KEIRCVCIYGGTVISEQIAKLKYGAEILVCTPGRMIDMMAVNGGRVTNMRRCTFLVLDEADRMFDMGFEPQVLTILGHIRPDRQTVMFSATFPRKMEALARKVLNNPIEIEVGGKSIVCQDVSQNALILDETEKFNKLLELLGLYQEGGKVIVFVEKQENADRLIPLLIERGYICAAVHGGIDQDDRDSFISNFKTGRNPLLIATSVAARGLDVTDLNLVVNYDCPNHYEDYVHRCGRTGRAGNKGVAYTFVTPDQEKYIGDVIKAFKLSGATPPEDLVVAYDKFKERMKQEGKKVFSSSGFKGKGFQFDEAESQLAYERRKFERETLGLEDSDEEVNLDDKIID--MFAVKRNITNVDRNSIVKSAPSAATVASDQATHLLNKRLEAARQQAMKIDVQRKLGQVTKDQTQVTAQAVFSGGVIMQNGTRLVNSNPVSGKDLAAQKAEEIHNKLGYSKSDAGEDEMKDGLNMVRKYEEELEINDFASNVRYRLTSKETMTNLSEYYDVGVSVRGLYM-PTHIKHKMEQNGERPLYLSLESVSEIKIQAAKKEIIRIIKEEL-----LKLQKVGHTVVQGRYKV 963
[Close]
BLAST of Pre-mRNA-processing ATP-dependent RNA helicase PRP5 vs. Planmine SMEST
Match: SMESG000033916.1 (SMESG000033916.1)

HSP 1 Score: 345.51 bits (885), Expect = 5.635e-107
Identity = 174/432 (40.28%), Postives = 276/432 (63.89%), Query Frame = 2 
Query:  878 YDFNLYKEVPEISKMTTKEVKELRRSMAIVVKGKECPKPITKWSHAIVSMKILNALKYNKMNEPTPIQSQTIPAIMSGKDVIGIAKTGSGKTLSYLLPLIRHIHNQPNVTVGEGPIAIVLCPTRELSIQIHQEIEKITYALRDVNCGCIYGGADTAQQISRLKRGVEIVVGTPGRIIDIMATNGGRNLSLSRCTFIVLDEADRMFDMGFEPQVMAIISRIRPDRQTVMFSATFPRRIEAVAKKIMKEPIEVRVDGGNKVCT--DVVQHVYLLDENDKFLKLVELLSEFKYRGKSLVFVETQETAQILSSNLTHQGFEVSMIHGGLTQEKREEGMFNFKSGTVPILIATSIAARGLDVNDLMMVVNYDCPNHYEDYVHRCGRTGRAGNKGYSYTFVTSDQEVMIGNLIKALKENGQEIPGELTE-AYARYTER 2164
            ++ N Y+E P +S  ++ E++  RR   + VKG    KPI  ++   +S +I++ ++ NK NEPTPIQ+Q +P  +SG++++G+A+TGSGKT SYL+P I H+  QP +  G+GPI +++ PTREL+ Q+         ++  +   C+YGGA+   QI +L+ G EI+V TPGR+ID++ ++     +L R T++VLDEADRM DMGFEPQ+  I S++R DRQT+M+SAT+P+ ++ +A+  + + I+V + G  ++    ++ Q V +LDE  K  +L+E++S+   R K +VF ET++ A ++ S L  + F V  +HG  +Q  RE  +  F+   + IL+AT +A+RGLDV+D+ +V+NYD P  +EDY+HR GRTGR G  G SYTF           L+K ++E  Q +   L + AY   +ER
Sbjct:   93 FEKNFYRENPVVSNRSSSEIENYRRLKEMTVKGDNINKPIFSFNEIDLSREIMSVIRNNKWNEPTPIQAQGLPMALSGRNLVGVARTGSGKTASYLIPAIVHLKAQPPLRRGDGPICLIVVPTRELAQQVQTVANDFCESV-GIRSVCVYGGANKGDQIRQLRNGAEIIVATPGRLIDLLKSSI---TNLHRTTYVVLDEADRMLDMGFEPQIRKIFSQVRQDRQTLMWSATWPKEVQRLAQDFLGKYIQVNI-GSQELHANPNIEQIVEILDEYSKDKRLLEVVSKTP-RDKMIVFAETKKKADMICSFLRSKQFRVGAMHGDKSQSDREYILNGFRGENLNILVATDVASRGLDVDDIKVVINYDFPIQFEDYIHRIGRTGRRGKSGVSYTFFNRKNSKSARQLVKVMEEANQSVSDSLYDLAYIPRSER 518
[Close]
BLAST of Pre-mRNA-processing ATP-dependent RNA helicase PRP5 vs. Planmine SMEST
Match: SMESG000033908.1 (SMESG000033908.1)

HSP 1 Score: 345.51 bits (885), Expect = 9.316e-107
Identity = 176/434 (40.55%), Postives = 277/434 (63.82%), Query Frame = 2 
Query:  878 YDFNLYKEVPEISKMTTKEVKELRRSMAIVVKGKECPKPITKWSHAIVSMKILNALKYNKMNEPTPIQSQTIPAIMSGKDVIGIAKTGSGKTLSYLLPLIRHIHNQPNVTVGEGPIAIVLCPTRELSIQIHQEIEKI--TYALRDVNCGCIYGGADTAQQISRLKRGVEIVVGTPGRIIDIMATNGGRNLSLSRCTFIVLDEADRMFDMGFEPQVMAIISRIRPDRQTVMFSATFPRRIEAVAKKIMKEPIEVRVDGGNKVCT--DVVQHVYLLDENDKFLKLVELLSEFKYRGKSLVFVETQETAQILSSNLTHQGFEVSMIHGGLTQEKREEGMFNFKSGTVPILIATSIAARGLDVNDLMMVVNYDCPNHYEDYVHRCGRTGRAGNKGYSYTFVTSDQEVMIGNLIKALKENGQEIPGELTE-AYARYTER 2164
            ++ N Y+E P +S  ++ E++  RR   + VKG    KPI  ++   +S +I++ ++ NK NEPTPIQ+Q +P  +SG++++G+A+TGSGKT SYL+P I H+  QP +  G+GPI +++ PTREL+ Q+         +  +R V   C+YGGA+   QI +L+ G EI+V TPGR+ID++ ++     +L R T++VLDEADRM DMGFEPQ+  I S++R DRQT+M+SAT+P+ ++ +A+  + + I+V + G  ++    ++ Q V +LDE  K  +L+E++S+   R K +VF ET++ A ++ S L  + F V  +HG  +Q  RE  +  F+   + IL+AT +A+RGLDV+D+ +V+NYD P  +EDY+HR GRTGR G  G SYTF           L+K ++E  Q +   L + AY   +ER
Sbjct:   99 FEKNFYRENPVVSNRSSSEIENYRRLKEMTVKGDNINKPIFSFNEIDLSREIMSVIRNNKWNEPTPIQAQGLPMALSGRNLVGVARTGSGKTASYLIPAIVHLKAQPPLRRGDGPICLIVVPTRELAQQVQTVANDFCESVGIRSV---CVYGGANKGDQIRQLRSGAEIIVATPGRLIDLLKSSI---TNLHRTTYVVLDEADRMLDMGFEPQIRKIFSQVRQDRQTLMWSATWPKEVQRLAQDFLGKYIQVNI-GSQELHANPNIEQIVEILDEYSKDKRLLEVVSKTP-RDKMIVFAETKKKADMICSFLRSKQFRVGAMHGDKSQSDREYILNGFRGENLNILVATDVASRGLDVDDIKVVINYDFPIQFEDYIHRIGRTGRRGKSGVSYTFFNRKNSKSARQLVKVMEEANQSVSDSLYDLAYIPRSER 524
[Close]
BLAST of Pre-mRNA-processing ATP-dependent RNA helicase PRP5 vs. Planmine SMEST
Match: SMESG000012031.1 (SMESG000012031.1)

HSP 1 Score: 354.369 bits (908), Expect = 9.044e-104
Identity = 186/448 (41.52%), Postives = 273/448 (60.94%), Query Frame = 2 
Query:  824 EKKQKLPDVNHDKVYYRKYDFNLYKEVPEISKMTTKEVKELRRSMAIVVKGKECPKPITKWSHAIVSMKILNALKYNKMNEPTPIQSQTIPAIMSGKDVIGIAKTGSGKTLSYLLPLIRHIHNQPNVTVGEGPIAIVLCPTRELSIQIHQ-EIEKITYALRDVNCGCIYGGADTAQQISRLKRGVEIVVGTPGRIIDIMATNGGRNLSLSRCTFIVLDEADRMFDMGFEPQVMAIISRIRPDRQTVMFSATFPRRIEAVAKKIMKEPIEVRVDGGN---KVCTDVVQHVYLLDENDKFLKLVELLSEFKYRGKSLVFVETQETAQILSSNLTHQGFEVSMIHGGLTQEKREEGMFNFKSGTVPILIATSIAARGLDVNDLMMVVNYDCPNHYEDYVHRCGRTGRAGNKGYSYTFVT--SDQEVMIGNLIKALKENGQEIPGELTEAYA 2149
            E K K PD N   +   K++ N YKE+  +      EV++ R+   I + G+  P P+  +        I+NA+K N+  +PT IQSQ  P  +SG DV+GIA+TGSGKT S+LLP I HI  QP V  G+GPI ++L PTREL+ Q+ +  IE   YA   +   C YGGA    QI +L +  E+V+ TPGR+ID +     +  +L RCT++VLDEADRM DMGFEP +  I+S++RPDRQT+M+SAT+P  ++ +A   +K  +++ V  G+       D+ Q V +LDE +K  +L+E+L + K R +SLVF ET+     L   +  +G +   +HG   Q +RE+ + +F+ G   +LIAT +A+RGLD++D+  V+NYD P+  EDY+HR GRT R+G KG +YTF     D+     +LI  L+E  QE+P EL +  +
Sbjct:   21 ENKLKPPDWND--IQLMKFEKNFYKEISVVRNRNVSEVEKFRKENNITIIGENVPNPVLCFEEVQFPNFIMNAIKDNRWIKPTAIQSQGWPMALSGSDVVGIAQTGSGKTASFLLPAIVHIEAQPPVQSGDGPICLILVPTRELAQQVEKVAIEFSEYAK--IKIACCYGGASRNSQIHQLNKNPEVVIATPGRLIDFL---NDKITNLRRCTYLVLDEADRMLDMGFEPDIRKIVSQVRPDRQTLMWSATWPNEVQNLASDFLKNYVQINV--GSLYLHANPDIKQKVEILDEKEKEERLIEILCDNK-RKRSLVFSETKRKVDDLCRIIVRKGIDCMAMHGDKVQREREKVLQDFRDGRCYVLIATDVASRGLDIDDIEYVINYDYPSKLEDYIHRIGRTARSGKKGIAYTFFNPMKDKPRQAQDLIMILEEAKQEVPTELRDVAS 458
The following BLAST results are available for this feature:
BLAST of Pre-mRNA-processing ATP-dependent RNA helicase PRP5 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
DDX461.067e-17840.10DEAD-box helicase 46 [Source:HGNC Symbol;Acc:HGNC:... [more]
DDX461.385e-17840.05DEAD-box helicase 46 [Source:HGNC Symbol;Acc:HGNC:... [more]
DDX171.042e-11244.79DEAD-box helicase 17 [Source:HGNC Symbol;Acc:HGNC:... [more]
DDX171.097e-11244.79DEAD-box helicase 17 [Source:HGNC Symbol;Acc:HGNC:... [more]
DDX171.097e-11244.79DEAD-box helicase 17 [Source:HGNC Symbol;Acc:HGNC:... [more]
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BLAST of Pre-mRNA-processing ATP-dependent RNA helicase PRP5 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
F53H1.10.000e+040.60pep chromosome:WBcel235:IV:1297222:1309652:-1 gene... [more]
F53H1.11.020e-17149.12pep chromosome:WBcel235:IV:1297400:1309644:-1 gene... [more]
F53H1.11.978e-11938.59pep chromosome:WBcel235:IV:1297283:1309644:-1 gene... [more]
F53H1.17.529e-10950.62pep chromosome:WBcel235:IV:1297400:1309644:-1 gene... [more]
C46F11.44.998e-10840.32pep chromosome:WBcel235:III:3657716:3664494:-1 gen... [more]
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BLAST of Pre-mRNA-processing ATP-dependent RNA helicase PRP5 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
CG62279.397e-16250.82gene:FBgn0030631 transcript:FBtr0074011[more]
CG64188.259e-10938.90gene:FBgn0036104 transcript:FBtr0076274[more]
CG100773.595e-10541.24gene:FBgn0035720 transcript:FBtr0333083[more]
CG100773.595e-10541.24gene:FBgn0035720 transcript:FBtr0076940[more]
mahe1.408e-10042.72gene:FBgn0029979 transcript:FBtr0071132[more]
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BLAST of Pre-mRNA-processing ATP-dependent RNA helicase PRP5 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ddx461.414e-17650.29DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Source:... [more]
ddx52.326e-11543.43DEAD (Asp-Glu-Ala-Asp) box helicase 5 [Source:ZFIN... [more]
ddx51.343e-11343.43DEAD (Asp-Glu-Ala-Asp) box helicase 5 [Source:ZFIN... [more]
DDX177.442e-11243.33si:dkey-156n14.5 [Source:ZFIN;Acc:ZDB-GENE-030131-... [more]
ddx425.109e-11142.30DEAD (Asp-Glu-Ala-Asp) box helicase 42 [Source:ZFI... [more]
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BLAST of Pre-mRNA-processing ATP-dependent RNA helicase PRP5 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
DDX469.067e-17452.21DEAD-box helicase 46 [Source:NCBI gene;Acc:1001453... [more]
DDX469.753e-17452.21DEAD-box helicase 46 [Source:NCBI gene;Acc:1001453... [more]
DDX466.757e-16240.40DEAD-box helicase 46 [Source:NCBI gene;Acc:1001453... [more]
ddx171.359e-11643.56DEAD-box helicase 17 [Source:NCBI gene;Acc:549535][more]
ddx172.275e-11643.56DEAD-box helicase 17 [Source:NCBI gene;Acc:549535][more]
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BLAST of Pre-mRNA-processing ATP-dependent RNA helicase PRP5 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Ddx462.266e-17939.95DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Source:... [more]
Ddx462.266e-17939.95DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Source:... [more]
Ddx465.214e-16138.03DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Source:... [more]
Ddx178.683e-11444.39DEAD (Asp-Glu-Ala-Asp) box polypeptide 17 [Source:... [more]
Ddx179.177e-11444.39DEAD (Asp-Glu-Ala-Asp) box polypeptide 17 [Source:... [more]
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BLAST of Pre-mRNA-processing ATP-dependent RNA helicase PRP5 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q62780|DDX46_RAT1.004e-17841.99Probable ATP-dependent RNA helicase DDX46 OS=Rattu... [more]
sp|Q569Z5|DDX46_MOUSE1.585e-17839.95Probable ATP-dependent RNA helicase DDX46 OS=Mus m... [more]
sp|Q7L014|DDX46_HUMAN5.123e-17840.10Probable ATP-dependent RNA helicase DDX46 OS=Homo ... [more]
sp|Q5R6D8|DDX46_PONAB1.328e-17639.92Probable ATP-dependent RNA helicase DDX46 OS=Pongo... [more]
sp|Q4TVV3|DDX46_DANRE7.363e-17650.19Probable ATP-dependent RNA helicase DDX46 OS=Danio... [more]
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BLAST of Pre-mRNA-processing ATP-dependent RNA helicase PRP5 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A564YRS80.000e+042.35Uncharacterized protein OS=Hymenolepis diminuta OX... [more]
A0A1S3JX530.000e+044.15probable ATP-dependent RNA helicase DDX46 isoform ... [more]
A0A1S3JXV80.000e+044.15probable ATP-dependent RNA helicase DDX46 isoform ... [more]
A0A3B5LBR60.000e+043.70DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 OS=Xipho... [more]
A0A0R3T2P00.000e+042.63Uncharacterized protein OS=Rodentolepis nana OX=10... [more]
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BLAST of Pre-mRNA-processing ATP-dependent RNA helicase PRP5 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ddx463.600e-17850.68DEAD-box helicase 46 [Source:NCBI gene;Acc:1030417... [more]
ddx467.307e-16348.36DEAD-box helicase 46 [Source:NCBI gene;Acc:1030417... [more]
DDX53.427e-11443.57probable ATP-dependent RNA helicase DDX5 [Source:N... [more]
ddx51.659e-11343.33probable ATP-dependent RNA helicase DDX5 [Source:N... [more]
ddx422.737e-10839.74DEAD-box helicase 42 [Source:NCBI gene;Acc:1030444... [more]
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BLAST of Pre-mRNA-processing ATP-dependent RNA helicase PRP5 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ddx460.000e+041.67DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Source:... [more]
ddx421.090e-10235.68DEAD (Asp-Glu-Ala-Asp) box helicase 42 [Source:ZFI... [more]
ddx234.085e-8838.08DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Source:... [more]
ENSPMAT00000003898.16.512e-8836.84pep scaffold:Pmarinus_7.0:GL481305:13824:21767:-1 ... [more]
ddx593.501e-6330.65DEAD (Asp-Glu-Ala-Asp) box polypeptide 59 [Source:... [more]
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BLAST of Pre-mRNA-processing ATP-dependent RNA helicase PRP5 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 5
Match NameE-valueIdentityDescription
DBP21.500e-10541.13ATP-dependent RNA helicase of the DEAD-box protein... [more]
PRP54.478e-9932.95RNA helicase in the DEAD-box family; necessary for... [more]
DBP17.987e-8537.56Putative ATP-dependent RNA helicase of the DEAD-bo... [more]
DED14.975e-8437.41ATP-dependent DEAD (Asp-Glu-Ala-Asp)-box RNA helic... [more]
DBP36.584e-7637.77RNA-Dependent ATPase, member of DExD/H-box family;... [more]
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BLAST of Pre-mRNA-processing ATP-dependent RNA helicase PRP5 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO428944.035e-17842.21Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO380611.617e-10841.37Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO435571.267e-10739.26Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO436025.059e-8838.15Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO396991.483e-8039.47Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Pre-mRNA-processing ATP-dependent RNA helicase PRP5 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ddx462.243e-18047.77DEAD-box helicase 46 [Source:NCBI gene;Acc:1011615... [more]
ddx462.721e-17947.77DEAD-box helicase 46 [Source:NCBI gene;Acc:1011615... [more]
ddx51.276e-11543.66probable ATP-dependent RNA helicase DDX5 [Source:N... [more]
DDX54.759e-11442.96probable ATP-dependent RNA helicase DDX5 [Source:N... [more]
si:dkey-156n14.51.549e-11243.43probable ATP-dependent RNA helicase DDX17 [Source:... [more]
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BLAST of Pre-mRNA-processing ATP-dependent RNA helicase PRP5 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000075674.10.000e+099.87SMESG000075674.1[more]
SMESG000079612.10.000e+046.01SMESG000079612.1[more]
SMESG000033916.15.635e-10740.28SMESG000033916.1[more]
SMESG000033908.19.316e-10740.55SMESG000033908.1[more]
SMESG000012031.19.044e-10441.52SMESG000012031.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30008892 ID=SMED30008892|Name=Pre-mRNA-processing ATP-dependent RNA helicase PRP5|organism=Schmidtea mediterranea sexual|type=transcript|length=3155bp
TTTGTTTCAATATTCTTTAAGGTGTTTATTTCAATCATCACACTGTCCTT
GTTTTTCTGCCTACTTAAAGCTTAACAGTATTGATTGATTTTGTTTAAAC
GTTTTAACGAAAACTCAAACTTGTTATAATTGTAAGTCTTAAATTAGATA
TTTTATCATGTATTCCGATAAATTAATCCAAGACAATGATACTGAAGATG
ACAAACGACGAAAGATTCGAGAATCAAAAGATAAAAAAAAGCGATCTAAA
TCCAAAGAACGCCGACGAGAACGGTCTCGATCTCGCTCTAAAGATCGAAA
ACGACGAAGATCTCGATCAGTTGAAAGAAGTAAAGATAGAAGAAAGTCTA
GGTCAAAGGAACGGGAAAGAGTAAGACGTAAGTCGAAAGAAAGACGAGAA
AGATCGAAATCAAGAGAAGATAGAAGAGATCGCAAAGATGATAAATTTAA
AAAGTACAAAAAGGAAAAGTCACCCGAAAAATCAATGGAAAAGTCATTGA
AGAAAGATAATAAAAAAGAACTAGCAGAAGATGTTGCAGCTGAAGATCCT
CCAGCTTTAGACTATGATTCTGATGATTTTGTAGAAATGCTACCAAAGTC
GACATCAGTAATTCCAGTTGTCAAAGAATCAGACAAGGAAAATACTGTCG
ATACCGATGTTGATTCTATTGATGCATATATGTCAACGTTGATAAAAACC
GTAAAGGATCCAAGTATAGCGAAAATTGGTGAGTTCACCGATGATCACAT
TGAAGATACTGATGAATACCATCAAACTGTTGAACCCGAAACACTCGAAT
CTATAACTCAAGCTTTATTCGAGGAAAAGAAGCAGAAGTTGCCTGATGTT
AACCACGATAAAGTTTATTATCGAAAATATGACTTTAATTTATATAAAGA
AGTTCCAGAGATTTCTAAAATGACAACAAAAGAAGTTAAAGAATTAAGAA
GGTCAATGGCAATAGTTGTTAAAGGAAAGGAATGCCCAAAACCCATTACT
AAGTGGTCACATGCAATTGTGTCGATGAAGATTTTAAATGCATTAAAATA
CAATAAAATGAATGAACCAACACCAATCCAATCTCAAACAATTCCAGCAA
TAATGAGTGGAAAAGATGTGATAGGTATTGCAAAAACCGGAAGTGGAAAG
ACTCTGTCATATTTGCTGCCATTAATCCGACATATACACAATCAACCAAA
TGTTACTGTCGGAGAGGGTCCAATAGCCATTGTCTTGTGTCCCACAAGAG
AGTTGAGTATCCAGATACATCAAGAAATCGAAAAGATCACATATGCATTA
AGAGATGTAAACTGCGGTTGCATTTATGGTGGAGCTGATACTGCACAGCA
AATAAGTCGATTAAAACGAGGTGTTGAAATCGTAGTTGGAACTCCAGGCC
GAATCATTGACATAATGGCTACGAATGGAGGAAGGAATTTGAGTTTAAGT
CGATGCACATTTATCGTTCTCGATGAAGCTGATCGAATGTTTGACATGGG
ATTTGAACCTCAAGTCATGGCGATTATCAGCAGAATTAGACCGGACCGAC
AAACTGTTATGTTCAGTGCAACATTTCCAAGGAGAATTGAGGCAGTTGCC
AAGAAGATTATGAAAGAGCCAATTGAAGTGCGAGTTGACGGAGGAAACAA
AGTCTGTACCGATGTAGTTCAACACGTGTATCTATTAGACGAGAACGATA
AATTCTTGAAGTTGGTAGAATTGTTAAGCGAATTCAAATATCGAGGAAAG
AGTTTAGTTTTTGTCGAAACCCAGGAAACTGCTCAAATATTATCAAGCAA
TCTTACTCATCAGGGATTTGAAGTGTCGATGATTCACGGCGGCCTGACAC
AAGAAAAACGAGAAGAAGGAATGTTCAATTTTAAATCCGGAACCGTTCCT
ATATTAATCGCAACCTCGATTGCTGCAAGGGGATTGGACGTTAACGATTT
AATGATGGTCGTCAATTACGACTGTCCGAATCACTATGAGGACTATGTGC
ATCGATGCGGTCGAACCGGAAGAGCAGGAAACAAAGGATATTCATATACA
TTTGTTACATCGGACCAGGAAGTAATGATTGGCAATTTGATAAAGGCGTT
GAAGGAAAACGGACAAGAAATACCCGGTGAACTAACGGAAGCTTATGCAC
GTTACACGGAAAGAATGGTATTGGAAGGTAAAACTATCAAAGCTCCATCG
GGATTTCGTGGTCATGGTTACAAATTTGACGCTGCTGAAGCAATGAAAGA
AAAGGGTAAAAAGCTTCAGGAGCTGTTCAAATACTGCCCAGAAGAAATAA
CCGAAGAAGATGAAGCTGTACTGGAAGAAATGCAATTAACATCTCAACGC
ACATCTCACCAACTTAATGCTAACCCTCTCGTTCCTCAAATCCCTTCATA
TGAAGCTCAAAATCACGCTAAAGCCGCCCATCAAATGGCCATGAAACTGA
ACATGAAACTCGACAGTACAGGAAGTGTTGTCGAACCATCCGGAGACATT
GCACCGTCATCAAGAGAAGAAATACCGATTAACAATTTACCGGCTAATAT
TCGATATTTGCTAACAACTAGAGATCTTCGTACGAATCTCAGTGAAAATT
TCGATGTCGCTCTGACTGTAAAAGGAGTTTTTATGGCACCGAAAGACATC
AAAAAGCTTGAACAAATCGGAGAGAAACCTCTGCACTTGGTTCTCGAATC
AGATTCTCCAATCAACATTAGATCGGCCAGAAACGAAATCTGCAGGGTTG
TCAAAGAAGCTATGAAAAAATAGATTAATTTATCAGCTAATAAAATGTTT
TATTGAATTATCATGATGCGTTTTTCTGTTTGGAAAAAAAAGTTGTTTGC
AACTGAATTGTCCAAAAAAATACAATTTTCATCCAGTTGTTTAATTTGTA
CGCATTGGGGCATATTACAAATCTGATGGAAGATCTGTGAATGAATATAT
TTTCTTTGACCAAACTAGCTGCGTCTCAACTATTTGAAACGCGCTTGTAC
AGTATTGTTGGGTAGAATAAATGGAATTTTTCTAATTTCTTTTAATGCTA
TTGATATCGATTTTCTAGATAAATATTTGATTTCTCCACGGATAAATCCG
TTATGGTTAGGTAGGAGCGTAACTGAATTCTCGGATGCACTCAAGTCATT
TCAAC
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protein sequence of SMED30008892-orf-1

>SMED30008892-orf-1 ID=SMED30008892-orf-1|Name=SMED30008892-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=872bp
MYSDKLIQDNDTEDDKRRKIRESKDKKKRSKSKERRRERSRSRSKDRKRR
RSRSVERSKDRRKSRSKERERVRRKSKERRERSKSREDRRDRKDDKFKKY
KKEKSPEKSMEKSLKKDNKKELAEDVAAEDPPALDYDSDDFVEMLPKSTS
VIPVVKESDKENTVDTDVDSIDAYMSTLIKTVKDPSIAKIGEFTDDHIED
TDEYHQTVEPETLESITQALFEEKKQKLPDVNHDKVYYRKYDFNLYKEVP
EISKMTTKEVKELRRSMAIVVKGKECPKPITKWSHAIVSMKILNALKYNK
MNEPTPIQSQTIPAIMSGKDVIGIAKTGSGKTLSYLLPLIRHIHNQPNVT
VGEGPIAIVLCPTRELSIQIHQEIEKITYALRDVNCGCIYGGADTAQQIS
RLKRGVEIVVGTPGRIIDIMATNGGRNLSLSRCTFIVLDEADRMFDMGFE
PQVMAIISRIRPDRQTVMFSATFPRRIEAVAKKIMKEPIEVRVDGGNKVC
TDVVQHVYLLDENDKFLKLVELLSEFKYRGKSLVFVETQETAQILSSNLT
HQGFEVSMIHGGLTQEKREEGMFNFKSGTVPILIATSIAARGLDVNDLMM
VVNYDCPNHYEDYVHRCGRTGRAGNKGYSYTFVTSDQEVMIGNLIKALKE
NGQEIPGELTEAYARYTERMVLEGKTIKAPSGFRGHGYKFDAAEAMKEKG
KKLQELFKYCPEEITEEDEAVLEEMQLTSQRTSHQLNANPLVPQIPSYEA
QNHAKAAHQMAMKLNMKLDSTGSVVEPSGDIAPSSREEIPINNLPANIRY
LLTTRDLRTNLSENFDVALTVKGVFMAPKDIKKLEQIGEKPLHLVLESDS
PINIRSARNEICRVVKEAMKK*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: molecular function
TermDefinition
GO:0003724RNA helicase activity
GO:0005524ATP binding
GO:0003676nucleic acid binding
GO:0000166nucleotide binding
GO:0003723RNA binding
GO:0004004ATP-dependent RNA helicase activity
GO:0004386helicase activity
GO:0016787hydrolase activity
GO:0016887ATPase activity
GO:1990446U1 snRNP binding
GO:1990447U2 snRNP binding
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000429neoblast
PLANA:0002109X1 cell
PLANA:0002111X2 cell
Vocabulary: INTERPRO
TermDefinition
IPR001650Helicase_C
IPR014001Helicase_ATP-bd
IPR027417P-loop_NTPase
IPR011545DEAD/DEAH_box_helicase_dom
IPR000629RNA-helicase_DEAD-box_CS
IPR014014RNA_helicase_DEAD_Q_motif
Vocabulary: biological process
TermDefinition
GO:0000398mRNA splicing, via spliceosome
GO:0006397mRNA processing
GO:0008380RNA splicing
GO:0010468regulation of gene expression
GO:0010501RNA secondary structure unwinding
GO:1903241U2-type prespliceosome assembly
Vocabulary: cellular component
TermDefinition
GO:0005634nucleus
GO:0005829cytosol
GO:0044732mitotic spindle pole body
GO:0071004U2-type prespliceosome
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR001650Helicase, C-terminalSMARTSM00490helicmild6coord: 543..624
e-value: 2.9E-28
score: 109.9
IPR001650Helicase, C-terminalPFAMPF00271Helicase_Ccoord: 514..624
e-value: 4.8E-28
score: 97.7
IPR001650Helicase, C-terminalPROSITEPS51194HELICASE_CTERcoord: 518..663
score: 22.131
IPR014001Helicase superfamily 1/2, ATP-binding domainSMARTSM00487ultradead3coord: 300..506
e-value: 3.5E-64
score: 229.2
IPR014001Helicase superfamily 1/2, ATP-binding domainPROSITEPS51192HELICASE_ATP_BIND_1coord: 312..491
score: 30.912
IPR011545DEAD/DEAH box helicase domainPFAMPF00270DEADcoord: 305..478
e-value: 5.9E-48
score: 163.0
NoneNo IPR availableGENE3DG3DSA:3.40.50.300coord: 492..666
e-value: 9.4E-52
score: 176.9
NoneNo IPR availableGENE3DG3DSA:3.40.50.300coord: 235..491
e-value: 2.5E-84
score: 284.5
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 66..80
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 1..135
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 81..127
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 22..58
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 7..21
NoneNo IPR availablePANTHERPTHR24031:SF25ATP-DEPENDENT RNA HELICASE DDX46-RELATEDcoord: 66..870
NoneNo IPR availablePANTHERPTHR24031RNA HELICASEcoord: 66..870
NoneNo IPR availableCDDcd18787SF2_C_DEADcoord: 503..633
e-value: 1.52253E-53
score: 180.011
NoneNo IPR availableCDDcd17953DEADc_DDX46coord: 271..491
e-value: 1.46649E-121
score: 364.776
IPR000629ATP-dependent RNA helicase DEAD-box, conserved sitePROSITEPS00039DEAD_ATP_HELICASEcoord: 437..445
IPR014014RNA helicase, DEAD-box type, Q motifPROSITEPS51195Q_MOTIFcoord: 281..309
score: 9.01
IPR027417P-loop containing nucleoside triphosphate hydrolaseSUPERFAMILYSSF52540P-loop containing nucleoside triphosphate hydrolasescoord: 354..641