Copper-transporting ATPase 1

Overview


Name	Copper-transporting ATPase 1
Smed ID	SMED30008855
Length (bp)	3467

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of Copper-transporting ATPase 1 (SMED30008855) t-SNE clustered cells

Violin plots show distribution of expression levels for Copper-transporting ATPase 1 (SMED30008855) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Copper-transporting ATPase 1 (SMED30008855) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Copper-transporting ATPase 1 (SMED30008855) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30008855

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 8

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
nervous system	SMED30008855	SMESG000058134.1	dd_Smed_v4_8956_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
gut	SMED30008855	SMESG000058134.1	dd_Smed_v4_8956_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cephalic ganglia	SMED30008855	SMESG000058134.1	dd_Smed_v4_8956_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
non-ciliated neuron	SMED30008855	SMESG000058134.1	dd_Smed_v4_8956_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
tail region	SMED30008855	SMESG000058134.1	dd_Smed_v6_8956_0_1	dd_Smed_v6	PMID:28171748 Stückemann et al., 2017
gut	SMED30008855	SMESG000058134.1	SMED30008855	smed_20140614	PMID:26457503 Tu et al., 2015
cephalic ganglia	SMED30008855	SMESG000058134.1	SMED30008855	smed_20140614	PMID:26457503 Tu et al., 2015
parenchyma	SMED30008855	SMESG000058134.1	SMED30008855	smed_20140614	PMID:26457503 Tu et al., 2015

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Homology

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BLAST of Copper-transporting ATPase 1 vs. Ensembl Human
Match: ATP7B (ATPase copper transporting beta [Source:HGNC Symbol;Acc:HGNC:870])

HSP 1 Score: 821.231 bits (2120), Expect = 0.000e+0
Identity = 450/931 (48.34%), Postives = 611/931 (65.63%), Query Frame = 1

Query:  259 LINKNKETDNTKELFKCHMRIQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMGFDAEIFQFKEHTKDIIEVMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKLAPKKTNKYN-DHVGESIKKWKHSFLISLIFGVPTMIVMMVFMYGFSHRMQVIHLKNGINVTVMVSNAPIXXXXXXXXXXXXXXXXXPVQFYGARYFYVQAYKSIKHGSANMDVLVVMATSVSYIYSFIVILVSMILRQDSSPQTFFETTPMLIVFLSLGRWLEHIAKGKTSEALSKLLSLQAFEATIIV--NDN---QERKISXXXXXXXXXXXXXPGEKIPIDGRVVSGKSRCDESLITGESMSVEKIPGSDVIGGTLNISGMLIIRATLVGEDSALNQIVKLVEEAQTSKAPIQELADKVAGLFVPGVIICSMFTLLIWIAIG----------YTNPNLLPGHSSINTDNTELIWKYAFQLAITVLSVACPCSLGLATPTAVMVGTGVGAINGILIKGGVPLEKMHQLDVIVFDKTGTITTGKPSVTNFVMCVENVTSQIRNCILLMLGAAESSSEHPIGKAILQYVRETCDINEMPQVVHSKSVSGFGLECSLKLQSDMFVPDSEIDNVLVKINDFQENNLTENLKET-SVKWRKINEPVEVVLYLGNRNMMKENHISIPDKLDELMSRDEDNGRTVVLMAIDKVLLAMISIADQVKKEAALVVYTLEKMGVEVFLLTGDNHKTATAIAKEIGIRNVFAEVLPSHKVAKIQQIQNMSKYKRSWLFSCCSKPSKLTNVAMVGDGINDSPALAQADVGIAIGTGTDVAVEAADVVLIRNSLLDVIAAMKLSKDTVRRIRQNFVAATMYNLIGIPIAAGALMPIGVVFMPWMA 3000
            ++ K+ ++       KC ++I+GMTC+SCV  IE  + K  GV S L+ L++   E+ YDP++I   +IA  I D+GF+A + +    +   IE+ I GMTC+SCV+ IESKL +  GI    VAL T K   KFDP+II PRDI+  IEE+GF A LA +  N ++ DH  E IK+WK SFL SL+FG+P M +M+  +   +   Q + L + I   + + N                     VQ  G  YFYVQAYKS++H SANMDVL+V+ATS++Y+YS ++++V++  + + SP TFF+T PML VF++LGRWLEH+AK KTSEAL+KL+SLQA EAT++    DN   +E ++ ++LV++GD+VKV+PG K P+DG+V+ G +  DESLITGE+M V K PGS VI G++N  G ++I+AT VG D+ L QIVKLVEEAQ SKAPIQ+LAD+ +G FVP +II S  TL++WI IG          + NPN        +   TE+I ++AFQ +ITVL +ACPCSLGLATPTAVMVGTGV A NGILIKGG PLE  H++  ++FDKTGTIT G P V   ++  +  T  +R  +L ++G AE+SSEHP+G A+ +Y +E      +      ++V G G+ C +          S ++ +L   ++   +    +L E  S+   K   P    + +GNR  ++ N ++I   + + M+  E  G+T +L+AID VL  MI+IAD VK+EAAL V+TL+ MGV+V L+TGDN KTA AIA ++GI  VFAEVLPSHKVAK+Q++QN  K                  VAMVGDG+NDSPALAQAD+G+AIGTGTDVA+EAADVVLIRN LLDV+A++ LSK TVRRIR N V A +YNL+GIPIAAG  MPIG+V  PWM 
Sbjct:  474 ILAKSPQSTRAVAPQKCFLQIKGMTCASCVSNIERNLQKEAGVLSVLVALMAGKAEIKYDPEVIQPLEIAQFIQDLGFEAAVMEDYAGSDGNIELTITGMTCASCVHNIESKLTRTNGITYASVALATSKALVKFDPEIIGPRDIIKIIEEIGFHASLAQRNPNAHHLDHKME-IKQWKKSFLCSLVFGIPVMALMIYMLIPSNEPHQSMVLDHNIIPGLSILNLIFFILCTF------------VQLLGGWYFYVQAYKSLRHRSANMDVLIVLATSIAYVYSLVILVVAVAEKAERSPVTFFDTPPMLFVFIALGRWLEHLAKSKTSEALAKLMSLQATEATVVTLGEDNLIIREEQVPMELVQRGDIVKVVPGGKFPVDGKVLEGNTMADESLITGEAMPVTKKPGSTVIAGSINAHGSVLIKATHVGNDTTLAQIVKLVEEAQMSKAPIQQLADRFSGYFVPFIIIMSTLTLVVWIVIGFIDFGVVQRYFPNPNK-------HISQTEVIIRFAFQTSITVLCIACPCSLGLATPTAVMVGTGVAAQNGILIKGGKPLEMAHKIKTVMFDKTGTITHGVPRVMRVLLLGDVATLPLRK-VLAVVGTAEASSEHPLGVAVTKYCKEELGTETLGYCTDFQAVPGCGIGCKV----------SNVEGILAH-SERPLSAPASHLNEAGSLPAEKDAVPQTFSVLIGNREWLRRNGLTISSDVSDAMTDHEMKGQTAILVAIDGVLCGMIAIADAVKQEAALAVHTLQSMGVDVVLITGDNRKTARAIATQVGINKVFAEVLPSHKVAKVQELQNKGK-----------------KVAMVGDGVNDSPALAQADMGVAIGTGTDVAIEAADVVLIRNDLLDVVASIHLSKRTVRRIRINLVLALIYNLVGIPIAAGVFMPIGIVLQPWMG 1355

HSP 2 Score: 112.079 bits (279), Expect = 3.271e-24
Identity = 53/152 (34.87%), Postives = 91/152 (59.87%), Query Frame = 1

Query:  313 MRIQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMGFDAEIFQFKEHT---------KDIIEVMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKLAPK 741
            +RI GMTC SCV +IE+++  LKG+ S  ++L      V Y P ++    +   I DMGF+A I + K  +         + ++++ ++GMTC SCV +IE K+ ++QG++ VKV+L+ ++    + P +I P D+ D + +MGF+A +  K
Sbjct:   62 VRILGMTCQSCVKSIEDRISNLKGIISMKVSLEQGSATVKYVPSVVCLQQVCHQIGDMGFEASIAEGKAASWPSRSLPAQEAVVKLRVEGMTCQSCVSSIEGKVRKLQGVVRVKVSLSNQEAVITYQPYLIQPEDLRDHVNDMGFEAAIKSK 213

HSP 3 Score: 92.4337 bits (228), Expect = 3.607e-18
Identity = 57/192 (29.69%), Postives = 86/192 (44.79%), Query Frame = 1

Query:  313 MRIQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMGFDAEI----------------FQFKEHTKDI----------------------IEVMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEM---GFDAKLAPKKTNKYNDH 765
            +R++GMTC SCV +IE +V KL+GV    ++L +    +TY P LI   D+ D +NDMGF+A I                 Q     + +                      +++ I GM C SCV  IE  + Q+ G+ S++V+L  +  + K+DP   SP  +  AIE +    F   L         DH
Sbjct:  147 LRVEGMTCQSCVSSIEGKVRKLQGVVRVKVSLSNQEAVITYQPYLIQPEDLRDHVNDMGFEAAIKSKVAPLSLGPIDIERLQSTNPKRPLSSANQNFNNSETLGHQGSHVVTLQLRIDGMHCKSCVLNIEENIGQLLGVQSIQVSLENKTAQVKYDPSCTSPVALQRAIEALPPGNFKVSLPDGAEGSGTDH 338

HSP 4 Score: 83.1889 bits (204), Expect = 2.258e-15
Identity = 51/180 (28.33%), Postives = 82/180 (45.56%), Query Frame = 1

Query:  310 HMRIQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLI----------------MASDIADTINDMGFDAEIFQFK----------EHTKDIIEVMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKLAPK--KTNKYNDH 765
             +RI GM C SCV  IE  + +L GV+S  ++L +   +V YDP                       + D     G D                 + T     + I GMTC+SCV++IE  ++Q++G+  + V+L        ++P +ISP ++  AIE+MGF+A +  +   TN   +H
Sbjct:  260 QLRIDGMHCKSCVLNIEENIGQLLGVQSIQVSLENKTAQVKYDPSCTSPVALQRAIEALPPGNFKVSLPDGAEGSGTDHRSSSSHSPGSPPRNQVQGTCSTTLIAIAGMTCASCVHSIEGMISQLEGVQQISVSLAEGTATVLYNPSVISPEELRAAIEDMGFEASVVSESCSTNPLGNH 439

HSP 5 Score: 58.151 bits (139), Expect = 1.159e-7
Identity = 26/72 (36.11%), Postives = 44/72 (61.11%), Query Frame = 1

Query:  541 VMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKLAPKKTNKY 756
            V I GMTC SCV +IE +++ ++GI+S+KV+L       K+ P ++  + +   I +MGF+A +A  K   +
Sbjct:   62 VRILGMTCQSCVKSIEDRISNLKGIISMKVSLEQGSATVKYVPSVVCLQQVCHQIGDMGFEASIAEGKAASW 133

[Close]

BLAST of Copper-transporting ATPase 1 vs. Ensembl Human
Match: ATP7A (ATPase copper transporting alpha [Source:HGNC Symbol;Acc:HGNC:869])

HSP 1 Score: 820.461 bits (2118), Expect = 0.000e+0
Identity = 459/931 (49.30%), Postives = 627/931 (67.35%), Query Frame = 1

Query:  274 KETDNTKELFKCHMRIQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMGFDAEIFQFKEHTKDIIEVMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKLAPK-KTNKYNDHVGESIKKWKHSFLISLIFGVPTM---IVMMVFMYGFS--HRMQVIHLKNGINVTVMVSNAPIXXXXXXXXXXXXXXXXXPVQFYGARYFYVQAYKSIKHGSANMDVLVVMATSVSYIYSFIVILVSMILRQDSSPQTFFETTPMLIVFLSLGRWLEHIAKGKTSEALSKLLSLQAFEATIIVNDN-----QERKISXXXXXXXXXXXXXPGEKIPIDGRVVSGKSRCDESLITGESMSVEKIPGSDVIGGTLNISGMLIIRATLVGEDSALNQIVKLVEEAQTSKAPIQELADKVAGLFVPGVIICSMFTLLIWIAIGYTN----PNLLPGHSSINTDNTELIWKYAFQLAITVLSVACPCSLGLATPTAVMVGTGVGAINGILIKGGVPLEKMHQLDVIVFDKTGTITTGKPSVTNFVMCVENVTSQIRNCILLMLGAAESSSEHPIGKAILQYVRETCDINEMPQVVHSKSVSGFGLEC------SLKLQSDMFVPDSEIDNV-LVKINDFQENNLTENLKETSVKWRKINEPVEVVLYLGNRNMMKENHISIPDKLDELMSRDEDNGRTVVLMAIDKVLLAMISIADQVKKEAALVVYTLEKMGVEVFLLTGDNHKTATAIAKEIGIRNVFAEVLPSHKVAKIQQIQNMSKYKRSWLFSCCSKPSKLTNVAMVGDGINDSPALAQADVGIAIGTGTDVAVEAADVVLIRNSLLDVIAAMKLSKDTVRRIRQNFVAATMYNLIGIPIAAGALMPIGVVFMPWMA 3000
            ++ +  K   KC++++ GMTC+SCV  IE  + + +G+ S L+ L++   EV Y+P +I    IA+ I ++GF A + +  +    ++E++++GMTC+SCV+ IES L + +GIL   VAL T K   K+DP+II PRDI+  IE +GF+A L  K ++  + DH  E I++W+ SFL+SL F +P M   I MMV  + F+  H  Q +  +  IN+   +     + PGLS+ NLL FL   PVQF+G  YFY+QAYK++KH +ANMDVL+V+AT++++ YS I++LV+M  R   +P TFF+T PML VF++LGRWLEHIAKGKTSEAL+KL+SLQA EATI+  D+      E ++ V+LV++GD++KV+PG K P+DGRV+ G S  DESLITGE+M V K PGS VI G++N +G L+I AT VG D+ L+QIVKLVEEAQTSKAPIQ+ ADK++G FVP ++  S+ TLL+WI IG+ N        PG++  +   TE I ++AFQ +ITVL +ACPCSLGLATPTAVMVGTGVGA NGILIKGG PLE  H++ V+VFDKTGTIT G P V N V  +        + IL ++G AES+SEHP+G AI +Y ++  D   +   +  + V G G+ C       L  +++  + D+ I N  LV+I+   E + T +      +        +  + +GNR  M  N + I + +++ M+  E  GRT VL+A+D  L  +I+IAD VK EA L ++ L+ MG+EV L+TGDN KTA +IA ++GI  VFAEVLPSHKVAK++Q+Q   K                  VAMVGDGINDSPALA A+VGIAIGTGTDVA+EAADVVLIRN LLDV+A++ LS+ TV+RIR NFV A +YNL+GIPIAAG  MPIG+V  PWM 
Sbjct:  479 QDKEEGKNSSKCYIQVTGMTCASCVANIERNLRREEGIYSILVALMAGKAEVRYNPAVIQPPMIAEFIRELGFGATVIENADEGDGVLELVVRGMTCASCVHKIESSLTKHRGILYCSVALATNKAHIKYDPEIIGPRDIIHTIESLGFEASLVKKDRSASHLDHKRE-IRQWRRSFLVSLFFCIPVMGLMIYMMVMDHHFATLHHNQNMSKEEMINLHSSMFLERQILPGLSVMNLLSFLLCVPVQFFGGWYFYIQAYKALKHKTANMDVLIVLATTIAFAYSLIILLVAMYERAKVNPITFFDTPPMLFVFIALGRWLEHIAKGKTSEALAKLISLQATEATIVTLDSDNILLSEEQVDVELVQRGDIIKVVPGGKFPVDGRVIEGHSMVDESLITGEAMPVAKKPGSTVIAGSINQNGSLLICATHVGADTTLSQIVKLVEEAQTSKAPIQQFADKLSGYFVPFIVFVSIATLLVWIVIGFLNFEIVETYFPGYNR-SISRTETIIRFAFQASITVLCIACPCSLGLATPTAVMVGTGVGAQNGILIKGGEPLEMAHKVKVVVFDKTGTITHGTP-VVNQVKVLTESNRISHHKILAIVGTAESNSEHPLGTAITKYCKQELDTETLGTCIDFQVVPGCGISCKVTNIEGLLHKNNWNIEDNNIKNASLVQIDASNEQSSTSSSMIIDAQISNALNAQQYKVLIGNREWMIRNGLVINNDVNDFMTEHERKGRTAVLVAVDDELCGLIAIADTVKPEAELAIHILKSMGLEVVLMTGDNSKTARSIASQVGITKVFAEVLPSHKVAKVKQLQEEGK-----------------RVAMVGDGINDSPALAMANVGIAIGTGTDVAIEAADVVLIRNDLLDVVASIDLSRKTVKRIRINFVFALIYNLVGIPIAAGVFMPIGLVLQPWMG 1389

HSP 2 Score: 97.0561 bits (240), Expect = 1.678e-19
Identity = 61/173 (35.26%), Postives = 84/173 (48.55%), Query Frame = 1

Query:  313 MRIQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMGFDAEI---------------------------------FQFKEHTKDIIEVMIQ--GMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDA 726
            + I GMTC+SCV +IE  + K  GVKS  ++L ++ G V YDP L     +   I DMGFDA +                                  Q KE  K+  +  IQ  GMTC+SCV  IE  L + +GI S+ VAL   K + +++P +I P  I + I E+GF A
Sbjct:  381 INIDGMTCNSCVQSIEGVISKKPGVKSIRVSLANSNGTVEYDPLLTSPETLRGAIEDMGFDATLSDTNEPLVVIAQPSSEMPLLTSTNEFYTKGMTPVQDKEEGKNSSKCYIQVTGMTCASCVANIERNLRREEGIYSILVALMAGKAEVRYNPAVIQPPMIAEFIRELGFGA 553

HSP 3 Score: 73.1738 bits (178), Expect = 3.110e-12
Identity = 47/162 (29.01%), Postives = 76/162 (46.91%), Query Frame = 1

Query:  313 MRIQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMGFDAEIFQFKEHTK-DIIEV-----------------------------MIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIE 708
            M+++GMTC SC  TIE ++ KL+GV+   ++L +    + Y P LI   ++   I  MGF A + +  ++ K   I+V                             +I GM C SCV  IES L+ +Q + S+ V+L       K++   ++P  +  AIE
Sbjct:  175 MKVEGMTCHSCTSTIEGKIGKLQGVQRIKVSLDNQEATIVYQPHLISVEEMKKQIEAMGFPAFVKKQPKYLKLGAIDVERLKNTPVKSSEGSQQRSPSYTNDSTATFIIDGMHCKSCVSNIESTLSALQYVSSIVVSLENRSAIVKYNASSVTPESLRKAIE 336

HSP 4 Score: 71.633 bits (174), Expect = 8.733e-12
Identity = 49/170 (28.82%), Postives = 80/170 (47.06%), Query Frame = 1

Query:  313 MRIQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMGFDAEIFQFKEHTKDIIEVMIQG--MTCSSCVYT----IESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKLAPKKTNKYNDH----VGESIKKWK 792
            + ++GMTC+SCV TIE Q+ K+ GV    ++L      + YDP L     + + I+DMGFDA I     H  D + V+     +T ++ +      I+S L + +G+  +K+            P I++   I + + E+  D     KK+    DH     GE + K K
Sbjct:   12 ISVEGMTCNSCVWTIEQQIGKVNGVHHIKVSLEEKNATIIYDPKLQTPKTLQEAIDDMGFDAVI-----HNPDPLPVLTDTLFLTVTASLTLPWDHIQSTLLKTKGVTDIKIYPQKRTVAVTIIPSIVNANQIKELVPELSLDTGTLEKKSGACEDHSMAQAGEVVLKMK 176

HSP 5 Score: 70.4774 bits (171), Expect = 1.839e-11
Identity = 47/164 (28.66%), Postives = 78/164 (47.56%), Query Frame = 1

Query:  319 IQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMG---FDAEIFQFKEH----------------------TKDIIEVMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKLA 735
            I GM C SCV  IE+ +  L+ V S +++L +    V Y+   +    +   I  +    +   I    E                       T++ + + I GMTC+SCV +IE  +++  G+ S++V+L    G  ++DP + SP  +  AIE+MGFDA L+
Sbjct:  283 IDGMHCKSCVSNIESTLSALQYVSSIVVSLENRSAIVKYNASSVTPESLRKAIEAVSPGLYRVSITSEVESTSNSPSSSSLQKIPLNVVSQPLTQETV-INIDGMTCNSCVQSIEGVISKKPGVKSIRVSLANSNGTVEYDPLLTSPETLRGAIEDMGFDATLS 445

HSP 6 Score: 70.4774 bits (171), Expect = 1.918e-11
Identity = 55/190 (28.95%), Postives = 95/190 (50.00%), Query Frame = 1

Query:  226 TLCEAIENLGF---LINKNKETDNTKELFKCHMRIQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMGFDAEIFQFK-----EHT-----KDIIEVMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKLAPKKTNKY 756
            TL EAI+++GF   + N +     T  LF   + +         H I++ +LK KGV    I        VT  P ++ A+ I + + ++  D    + K     +H+     + ++++ ++GMTC SC  TIE K+ ++QG+  +KV+L  ++    + P +IS  ++   IE MGF A +  KK  KY
Sbjct:   61 TLQEAIDDMGFDAVIHNPDPLPVLTDTLF---LTVTASLTLPWDH-IQSTLLKTKGVTDIKIYPQKRTVAVTIIPSIVNANQIKELVPELSLDTGTLEKKSGACEDHSMAQAGEVVLKMKVEGMTCHSCTSTIEGKIGKLQGVQRIKVSLDNQEATIVYQPHLISVEEMKKQIEAMGFPAFV--KKQPKY 244

HSP 7 Score: 65.4698 bits (158), Expect = 6.101e-10
Identity = 24/64 (37.50%), Postives = 47/64 (73.44%), Query Frame = 1

Query:  535 IEVMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDA 726
            + + ++GMTC+SCV+TIE ++ ++ G+  +KV+L  +     +DP++ +P+ + +AI++MGFDA
Sbjct:   10 VTISVEGMTCNSCVWTIEQQIGKVNGVHHIKVSLEEKNATIIYDPKLQTPKTLQEAIDDMGFDA 73

[Close]

BLAST of Copper-transporting ATPase 1 vs. Ensembl Human
Match: ATP7B (ATPase copper transporting beta [Source:HGNC Symbol;Acc:HGNC:870])

HSP 1 Score: 819.691 bits (2116), Expect = 0.000e+0
Identity = 450/931 (48.34%), Postives = 611/931 (65.63%), Query Frame = 1

Query:  259 LINKNKETDNTKELFKCHMRIQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMGFDAEIFQFKEHTKDIIEVMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKLAPKKTNKYN-DHVGESIKKWKHSFLISLIFGVPTMIVMMVFMYGFSHRMQVIHLKNGINVTVMVSNAPIXXXXXXXXXXXXXXXXXPVQFYGARYFYVQAYKSIKHGSANMDVLVVMATSVSYIYSFIVILVSMILRQDSSPQTFFETTPMLIVFLSLGRWLEHIAKGKTSEALSKLLSLQAFEATIIV--NDN---QERKISXXXXXXXXXXXXXPGEKIPIDGRVVSGKSRCDESLITGESMSVEKIPGSDVIGGTLNISGMLIIRATLVGEDSALNQIVKLVEEAQTSKAPIQELADKVAGLFVPGVIICSMFTLLIWIAIG----------YTNPNLLPGHSSINTDNTELIWKYAFQLAITVLSVACPCSLGLATPTAVMVGTGVGAINGILIKGGVPLEKMHQLDVIVFDKTGTITTGKPSVTNFVMCVENVTSQIRNCILLMLGAAESSSEHPIGKAILQYVRETCDINEMPQVVHSKSVSGFGLECSLKLQSDMFVPDSEIDNVLVKINDFQENNLTENLKET-SVKWRKINEPVEVVLYLGNRNMMKENHISIPDKLDELMSRDEDNGRTVVLMAIDKVLLAMISIADQVKKEAALVVYTLEKMGVEVFLLTGDNHKTATAIAKEIGIRNVFAEVLPSHKVAKIQQIQNMSKYKRSWLFSCCSKPSKLTNVAMVGDGINDSPALAQADVGIAIGTGTDVAVEAADVVLIRNSLLDVIAAMKLSKDTVRRIRQNFVAATMYNLIGIPIAAGALMPIGVVFMPWMA 3000
            ++ K+ ++       KC ++I+GMTC+SCV  IE  + K  GV S L+ L++   E+ YDP++I   +IA  I D+GF+A + +    +   IE+ I GMTC+SCV+ IESKL +  GI    VAL T K   KFDP+II PRDI+  IEE+GF A LA +  N ++ DH  E IK+WK SFL SL+FG+P M +M+  +   +   Q + L + I   + + N                     VQ  G  YFYVQAYKS++H SANMDVL+V+ATS++Y+YS ++++V++  + + SP TFF+T PML VF++LGRWLEH+AK KTSEAL+KL+SLQA EAT++    DN   +E ++ ++LV++GD+VKV+PG K P+DG+V+ G +  DESLITGE+M V K PGS VI G++N  G ++I+AT VG D+ L QIVKLVEEAQ SKAPIQ+LAD+ +G FVP +II S  TL++WI IG          + NPN        +   TE+I ++AFQ +ITVL +ACPCSLGLATPTAVMVGTGV A NGILIKGG PLE  H++  ++FDKTGTIT G P V   ++  +  T  +R  +L ++G AE+SSEHP+G A+ +Y +E      +      ++V G G+ C +          S ++ +L   ++   +    +L E  S+   K   P    + +GNR  ++ N ++I   + + M+  E  G+T +L+AID VL  MI+IAD VK+EAAL V+TL+ MGV+V L+TGDN KTA AIA ++GI  VFAEVLPSHKVAK+Q++QN  K                  VAMVGDG+NDSPALAQAD+G+AIGTGTDVA+EAADVVLIRN LLDV+A++ LSK TVRRIR N V A +YNL+GIPIAAG  MPIG+V  PWM 
Sbjct:  363 ILAKSPQSTRAVAPQKCFLQIKGMTCASCVSNIERNLQKEAGVLSVLVALMAGKAEIKYDPEVIQPLEIAQFIQDLGFEAAVMEDYAGSDGNIELTITGMTCASCVHNIESKLTRTNGITYASVALATSKALVKFDPEIIGPRDIIKIIEEIGFHASLAQRNPNAHHLDHKME-IKQWKKSFLCSLVFGIPVMALMIYMLIPSNEPHQSMVLDHNIIPGLSILNLIFFILCTF------------VQLLGGWYFYVQAYKSLRHRSANMDVLIVLATSIAYVYSLVILVVAVAEKAERSPVTFFDTPPMLFVFIALGRWLEHLAKSKTSEALAKLMSLQATEATVVTLGEDNLIIREEQVPMELVQRGDIVKVVPGGKFPVDGKVLEGNTMADESLITGEAMPVTKKPGSTVIAGSINAHGSVLIKATHVGNDTTLAQIVKLVEEAQMSKAPIQQLADRFSGYFVPFIIIMSTLTLVVWIVIGFIDFGVVQRYFPNPNK-------HISQTEVIIRFAFQTSITVLCIACPCSLGLATPTAVMVGTGVAAQNGILIKGGKPLEMAHKIKTVMFDKTGTITHGVPRVMRVLLLGDVATLPLRK-VLAVVGTAEASSEHPLGVAVTKYCKEELGTETLGYCTDFQAVPGCGIGCKV----------SNVEGILAH-SERPLSAPASHLNEAGSLPAEKDAVPQTFSVLIGNREWLRRNGLTISSDVSDAMTDHEMKGQTAILVAIDGVLCGMIAIADAVKQEAALAVHTLQSMGVDVVLITGDNRKTARAIATQVGINKVFAEVLPSHKVAKVQELQNKGK-----------------KVAMVGDGVNDSPALAQADMGVAIGTGTDVAIEAADVVLIRNDLLDVVASIHLSKRTVRRIRINLVLALIYNLVGIPIAAGVFMPIGIVLQPWMG 1244

HSP 2 Score: 112.079 bits (279), Expect = 3.914e-24
Identity = 53/152 (34.87%), Postives = 91/152 (59.87%), Query Frame = 1

Query:  313 MRIQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMGFDAEIFQFKEHT---------KDIIEVMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKLAPK 741
            +RI GMTC SCV +IE+++  LKG+ S  ++L      V Y P ++    +   I DMGF+A I + K  +         + ++++ ++GMTC SCV +IE K+ ++QG++ VKV+L+ ++    + P +I P D+ D + +MGF+A +  K
Sbjct:   62 VRILGMTCQSCVKSIEDRISNLKGIISMKVSLEQGSATVKYVPSVVCLQQVCHQIGDMGFEASIAEGKAASWPSRSLPAQEAVVKLRVEGMTCQSCVSSIEGKVRKLQGVVRVKVSLSNQEAVITYQPYLIQPEDLRDHVNDMGFEAAIKSK 213

HSP 3 Score: 57.7658 bits (138), Expect = 1.329e-7
Identity = 26/72 (36.11%), Postives = 44/72 (61.11%), Query Frame = 1

Query:  541 VMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKLAPKKTNKY 756
            V I GMTC SCV +IE +++ ++GI+S+KV+L       K+ P ++  + +   I +MGF+A +A  K   +
Sbjct:   62 VRILGMTCQSCVKSIEDRISNLKGIISMKVSLEQGSATVKYVPSVVCLQQVCHQIGDMGFEASIAEGKAASW 133

[Close]

BLAST of Copper-transporting ATPase 1 vs. Ensembl Human
Match: ATP7B (ATPase copper transporting beta [Source:HGNC Symbol;Acc:HGNC:870])

HSP 1 Score: 749.584 bits (1934), Expect = 0.000e+0
Identity = 428/931 (45.97%), Postives = 580/931 (62.30%), Query Frame = 1

Query:  259 LINKNKETDNTKELFKCHMRIQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMGFDAEIFQFKEHTKDIIEVMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKLAPKKTNKYN-DHVGESIKKWKHSFLISLIFGVPTMIVMMVFMYGFSHRMQVIHLKNGINVTVMVSNAPIXXXXXXXXXXXXXXXXXPVQFYGARYFYVQAYKSIKHGSANMDVLVVMATSVSYIYSFIVILVSMILRQDSSPQTFFETTPMLIVFLSLGRWLEHIAKGKTSEALSKLLSLQAFEATIIV--NDN---QERKISXXXXXXXXXXXXXPGEKIPIDGRVVSGKSRCDESLITGESMSVEKIPGSDVIGGTLNISGMLIIRATLVGEDSALNQIVKLVEEAQTSKAPIQELADKVAGLFVPGVIICSMFTLLIWIAIGY----------TNPNLLPGHSSINTDNTELIWKYAFQLAITVLSVACPCSLGLATPTAVMVGTGVGAINGILIKGGVPLEKMHQLDVIVFDKTGTITTGKPSVTNFVMCVENVTSQIRNCILLMLGAAESSSEHPIGKAILQYVRETCDINEMPQVVHSKSVSGFGLECSLKLQSDMFVPDSEIDNVLVKINDFQENNLTENLKET-SVKWRKINEPVEVVLYLGNRNMMKENHISIPDKLDELMSRDEDNGRTVVLMAIDKVLLAMISIADQVKKEAALVVYTLEKMGVEVFLLTGDNHKTATAIAKEIGIRNVFAEVLPSHKVAKIQQIQNMSKYKRSWLFSCCSKPSKLTNVAMVGDGINDSPALAQADVGIAIGTGTDVAVEAADVVLIRNSLLDVIAAMKLSKDTVRRIRQNFVAATMYNLIGIPIAAGALMPIGVVFMPWMA 3000
            ++ K+ ++       KC ++I+GMTC+SCV  IE  + K  GV S L+ L++   E+ YDP++I   +IA  I D+GF+A + +    +   IE+ I GMTC+SCV+ IESKL +  GI    VAL T K   KFDP+II PRDI+  IEE+GF A LA +  N ++ DH  E IK+WK SFL SL+FG+P M  +M++M                   ++ SN P                                     H S  +D  ++   S   I + I  ++   ++ + SP TFF+T PML VF++LGRWLEH+AK KTSEAL+KL+SLQA EAT++    DN   +E ++ ++LV++GD+VKV+PG K P+DG+V+ G +  DESLITGE+M V K PGS VI G++N  G ++I+AT VG D+ L QIVKLVEEAQ SKAPIQ+LAD+ +G FVP +II S  TL++WI IG+           NPN        +   TE+I ++AFQ +ITVL +ACPCSLGLATPTAVMVGTGV A NGILIKGG PLE  H++  ++FDKTGTIT G P V   ++  +  T  +R  +L ++G AE+SSEHP+G A+ +Y +E      +      ++V G G+ C +          S ++ +L   ++   +    +L E  S+   K   P    + +GNR  ++ N ++I   + + M+  E  G+T +L+AID VL  MI+IAD VK+EAAL V+TL+ MGV+V L+TGDN KTA AIA ++GI  VFAEVLPSHKVAK+Q++QN  K                  VAMVGDG+NDSPALAQAD+G+AIGTGTDVA+EAADVVLIRN LLDV+A++ LSK TVRRIR N V A +YNL+GIPIAAG  MPIG+V  PWM 
Sbjct:  474 ILAKSPQSTRAVAPQKCFLQIKGMTCASCVSNIERNLQKEAGVLSVLVALMAGKAEIKYDPEVIQPLEIAQFIQDLGFEAAVMEDYAGSDGNIELTITGMTCASCVHNIESKLTRTNGITYASVALATSKALVKFDPEIIGPRDIIKIIEEIGFHASLAQRNPNAHHLDHKME-IKQWKKSFLCSLVFGIPVM-ALMIYM-------------------LIPSNEP-------------------------------------HQSMVLDHNIIPGLS---ILNLIFFILCTFVQAERSPVTFFDTPPMLFVFIALGRWLEHLAKSKTSEALAKLMSLQATEATVVTLGEDNLIIREEQVPMELVQRGDIVKVVPGGKFPVDGKVLEGNTMADESLITGEAMPVTKKPGSTVIAGSINAHGSVLIKATHVGNDTTLAQIVKLVEEAQMSKAPIQQLADRFSGYFVPFIIIMSTLTLVVWIVIGFIDFGVVQRYFPNPNK-------HISQTEVIIRFAFQTSITVLCIACPCSLGLATPTAVMVGTGVAAQNGILIKGGKPLEMAHKIKTVMFDKTGTITHGVPRVMRVLLLGDVATLPLRK-VLAVVGTAEASSEHPLGVAVTKYCKEELGTETLGYCTDFQAVPGCGIGCKV----------SNVEGILAH-SERPLSAPASHLNEAGSLPAEKDAVPQTFSVLIGNREWLRRNGLTISSDVSDAMTDHEMKGQTAILVAIDGVLCGMIAIADAVKQEAALAVHTLQSMGVDVVLITGDNRKTARAIATQVGINKVFAEVLPSHKVAKVQELQNKGK-----------------KVAMVGDGVNDSPALAQADMGVAIGTGTDVAIEAADVVLIRNDLLDVVASIHLSKRTVRRIRINLVLALIYNLVGIPIAAGVFMPIGIVLQPWMG 1307

HSP 2 Score: 112.079 bits (279), Expect = 3.716e-24
Identity = 53/152 (34.87%), Postives = 91/152 (59.87%), Query Frame = 1

Query:  313 MRIQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMGFDAEIFQFKEHT---------KDIIEVMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKLAPK 741
            +RI GMTC SCV +IE+++  LKG+ S  ++L      V Y P ++    +   I DMGF+A I + K  +         + ++++ ++GMTC SCV +IE K+ ++QG++ VKV+L+ ++    + P +I P D+ D + +MGF+A +  K
Sbjct:   62 VRILGMTCQSCVKSIEDRISNLKGIISMKVSLEQGSATVKYVPSVVCLQQVCHQIGDMGFEASIAEGKAASWPSRSLPAQEAVVKLRVEGMTCQSCVSSIEGKVRKLQGVVRVKVSLSNQEAVITYQPYLIQPEDLRDHVNDMGFEAAIKSK 213

HSP 3 Score: 92.4337 bits (228), Expect = 3.716e-18
Identity = 57/192 (29.69%), Postives = 86/192 (44.79%), Query Frame = 1

Query:  313 MRIQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMGFDAEI----------------FQFKEHTKDI----------------------IEVMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEM---GFDAKLAPKKTNKYNDH 765
            +R++GMTC SCV +IE +V KL+GV    ++L +    +TY P LI   D+ D +NDMGF+A I                 Q     + +                      +++ I GM C SCV  IE  + Q+ G+ S++V+L  +  + K+DP   SP  +  AIE +    F   L         DH
Sbjct:  147 LRVEGMTCQSCVSSIEGKVRKLQGVVRVKVSLSNQEAVITYQPYLIQPEDLRDHVNDMGFEAAIKSKVAPLSLGPIDIERLQSTNPKRPLSSANQNFNNSETLGHQGSHVVTLQLRIDGMHCKSCVLNIEENIGQLLGVQSIQVSLENKTAQVKYDPSCTSPVALQRAIEALPPGNFKVSLPDGAEGSGTDH 338

HSP 4 Score: 83.1889 bits (204), Expect = 2.370e-15
Identity = 51/180 (28.33%), Postives = 82/180 (45.56%), Query Frame = 1

Query:  310 HMRIQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLI----------------MASDIADTINDMGFDAEIFQFK----------EHTKDIIEVMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKLAPK--KTNKYNDH 765
             +RI GM C SCV  IE  + +L GV+S  ++L +   +V YDP                       + D     G D                 + T     + I GMTC+SCV++IE  ++Q++G+  + V+L        ++P +ISP ++  AIE+MGF+A +  +   TN   +H
Sbjct:  260 QLRIDGMHCKSCVLNIEENIGQLLGVQSIQVSLENKTAQVKYDPSCTSPVALQRAIEALPPGNFKVSLPDGAEGSGTDHRSSSSHSPGSPPRNQVQGTCSTTLIAIAGMTCASCVHSIEGMISQLEGVQQISVSLAEGTATVLYNPSVISPEELRAAIEDMGFEASVVSESCSTNPLGNH 439

HSP 5 Score: 58.151 bits (139), Expect = 1.285e-7
Identity = 26/72 (36.11%), Postives = 44/72 (61.11%), Query Frame = 1

Query:  541 VMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKLAPKKTNKY 756
            V I GMTC SCV +IE +++ ++GI+S+KV+L       K+ P ++  + +   I +MGF+A +A  K   +
Sbjct:   62 VRILGMTCQSCVKSIEDRISNLKGIISMKVSLEQGSATVKYVPSVVCLQQVCHQIGDMGFEASIAEGKAASW 133

[Close]

BLAST of Copper-transporting ATPase 1 vs. Ensembl Human
Match: ATP7B (ATPase copper transporting beta [Source:HGNC Symbol;Acc:HGNC:870])

HSP 1 Score: 729.169 bits (1881), Expect = 0.000e+0
Identity = 419/969 (43.24%), Postives = 582/969 (60.06%), Query Frame = 1

Query:  319 IQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMGFDAEIFQFK--------------------------------------EHTKDIIE---------------VMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKLAPKKTNKYNDHVGESIKKWKHSFLISLIFGVPTMIVMMVFMYGFSHRMQVIHLKNGINVTVMVSNAPIXXXXXXXXXXXXXXXXXP------VQFYGARYFYVQAYKSIKHGSANMDVLVVMATSVSYIYSFIVILVSMILRQDSSPQTFFETTPMLIVFLSLGRWLEHIAKGKTSEALSKLLSLQAFEATIIV--NDN---QERKISXXXXXXXXXXXXXPGEKIPIDGRVVSGKSRCDESLITGESMSVEKIPGSDVIGGTLNISGMLIIRATLVGEDSALNQIVKLVEEAQTSKAPIQELADKVAGLFVPGVIICSMFTLLIWIAIGY----------TNPNLLPGHSSINTDNTELIWKYAFQLAITVLSVACPCSLGLATPTAVMVGTGVGAINGILIKGGVPLEKMHQLDVIVFDKTGTITTGKPSVTNFVMCVENVTSQIRNCILLMLGAAESSSEHPIGKAILQYVRETCDINEMPQVVHSKSVSGFGLECSLKLQSDMFVPDSEIDNVLVKINDFQENNLTENLKET-SVKWRKINEPVEVVLYLGNRNMMKENHISIPDKLDELMSRDEDNGRTVVLMAIDKVLLAMISIADQVKKEAALVVYTLEKMGVEVFLLTGDNHKTATAIAKEIGIRNVFAEVLPSHKVAKIQQIQNMSKYKRSWLFSCCSKPSKLTNVAMVGDGINDSPALAQADVGIAIGTGTDVAVEAADVVLIRNSLLDVIAAMKLSKDTVRRIRQNFVAATMYNLIGIPIAAGALMPIGVVFMPWMA 3000
            I GMTC+SCVH+IE  + +L+GV+   ++L      V Y+P +I   ++   I DMGF+A +                                           H  DI+                + I+GMTC+SCV  IE  L +  G+LSV VAL   K + K+DP++I P +I   I+++GF+A +         D+ G                       + + + G +    V ++++ +  T  ++ A +                 P      ++  G  YFYVQAYKS++H SANMDVL+V+ATS++Y+YS ++++V++  + + SP TFF+T PML VF++LGRWLEH+AK KTSEAL+KL+SLQA EAT++    DN   +E ++ ++LV++GD+VKV+PG K P+DG+V+ G +  DESLITGE+M V K PGS VI G++N  G ++I+AT VG D+ L QIVKLVEEAQ SKAPIQ+LAD+ +G FVP +II S  TL++WI IG+           NPN        +   TE+I ++AFQ +ITVL +ACPCSLGLATPTAVMVGTGV A NGILIKGG PLE  H++  ++FDKTGTIT G P V   ++  +  T  +R  +L ++G AE+SSEHP+G A+ +Y +E      +      ++V G G+ C +          S ++ +L   ++   +    +L E  S+   K   P    + +GNR  ++ N ++I   + + M+  E  G+T +L+AID VL  MI+IAD VK+EAAL V+TL+ MGV+V L+TGDN KTA AIA ++GI  VFAEVLPSHKVAK+Q++QN  K                  VAMVGDG+NDSPALAQAD+G+AIGTGTDVA+EAADVVLIRN LLDV+A++ LSK TVRRIR N V A +YNL+GIPIAAG  MPIG+V  PWM 
Sbjct:  365 IAGMTCASCVHSIEGMISQLEGVQQISVSLAEGTATVLYNPSVISPEELRAAIEDMGFEASVVSESCSTNPLGNHSAGNSMVQTTDGTPTSVQEVAPHTGRLPANHAPDILAKSPQSTRAVAPQKCFLQIKGMTCASCVSNIERNLQKEAGVLSVLVALMAGKAEIKYDPEVIQPLEIAQFIQDLGFEAAV-------MEDYAGSDGN-------------------IELTITGMTCASCVHNIESKLTRTNGITYASVALATSKALVKFDPEIIGPRDIIKIIELLGGWYFYVQAYKSLRHRSANMDVLIVLATSIAYVYSLVILVVAVAEKAERSPVTFFDTPPMLFVFIALGRWLEHLAKSKTSEALAKLMSLQATEATVVTLGEDNLIIREEQVPMELVQRGDIVKVVPGGKFPVDGKVLEGNTMADESLITGEAMPVTKKPGSTVIAGSINAHGSVLIKATHVGNDTTLAQIVKLVEEAQMSKAPIQQLADRFSGYFVPFIIIMSTLTLVVWIVIGFIDFGVVQRYFPNPNK-------HISQTEVIIRFAFQTSITVLCIACPCSLGLATPTAVMVGTGVAAQNGILIKGGKPLEMAHKIKTVMFDKTGTITHGVPRVMRVLLLGDVATLPLRK-VLAVVGTAEASSEHPLGVAVTKYCKEELGTETLGYCTDFQAVPGCGIGCKV----------SNVEGILAH-SERPLSAPASHLNEAGSLPAEKDAVPQTFSVLIGNREWLRRNGLTISSDVSDAMTDHEMKGQTAILVAIDGVLCGMIAIADAVKQEAALAVHTLQSMGVDVVLITGDNRKTARAIATQVGINKVFAEVLPSHKVAKVQELQNKGK-----------------KVAMVGDGVNDSPALAQADMGVAIGTGTDVAIEAADVVLIRNDLLDVVASIHLSKRTVRRIRINLVLALIYNLVGIPIAAGVFMPIGIVLQPWMG 1271

HSP 2 Score: 134.035 bits (336), Expect = 6.841e-31
Identity = 66/153 (43.14%), Postives = 95/153 (62.09%), Query Frame = 1

Query:  259 LINKNKETDNTKELFKCHMRIQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMGFDAEIFQFKEHTKDIIEVMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMG 717
            ++ K+ ++       KC ++I+GMTC+SCV  IE  + K  GV S L+ L++   E+ YDP++I   +IA  I D+GF+A + +    +   IE+ I GMTC+SCV+ IESKL +  GI    VAL T K   KFDP+II PRDI+  IE +G
Sbjct:  474 ILAKSPQSTRAVAPQKCFLQIKGMTCASCVSNIERNLQKEAGVLSVLVALMAGKAEIKYDPEVIQPLEIAQFIQDLGFEAAVMEDYAGSDGNIELTITGMTCASCVHNIESKLTRTNGITYASVALATSKALVKFDPEIIGPRDIIKIIELLG 626

HSP 3 Score: 112.079 bits (279), Expect = 3.227e-24
Identity = 53/152 (34.87%), Postives = 91/152 (59.87%), Query Frame = 1

Query:  313 MRIQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMGFDAEIFQFKEHT---------KDIIEVMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKLAPK 741
            +RI GMTC SCV +IE+++  LKG+ S  ++L      V Y P ++    +   I DMGF+A I + K  +         + ++++ ++GMTC SCV +IE K+ ++QG++ VKV+L+ ++    + P +I P D+ D + +MGF+A +  K
Sbjct:   62 VRILGMTCQSCVKSIEDRISNLKGIISMKVSLEQGSATVKYVPSVVCLQQVCHQIGDMGFEASIAEGKAASWPSRSLPAQEAVVKLRVEGMTCQSCVSSIEGKVRKLQGVVRVKVSLSNQEAVITYQPYLIQPEDLRDHVNDMGFEAAIKSK 213

HSP 4 Score: 92.4337 bits (228), Expect = 3.438e-18
Identity = 57/192 (29.69%), Postives = 86/192 (44.79%), Query Frame = 1

Query:  313 MRIQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMGFDAEI----------------FQFKEHTKDI----------------------IEVMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEM---GFDAKLAPKKTNKYNDH 765
            +R++GMTC SCV +IE +V KL+GV    ++L +    +TY P LI   D+ D +NDMGF+A I                 Q     + +                      +++ I GM C SCV  IE  + Q+ G+ S++V+L  +  + K+DP   SP  +  AIE +    F   L         DH
Sbjct:  147 LRVEGMTCQSCVSSIEGKVRKLQGVVRVKVSLSNQEAVITYQPYLIQPEDLRDHVNDMGFEAAIKSKVAPLSLGPIDIERLQSTNPKRPLSSANQNFNNSETLGHQGSHVVTLQLRIDGMHCKSCVLNIEENIGQLLGVQSIQVSLENKTAQVKYDPSCTSPVALQRAIEALPPGNFKVSLPDGAEGSGTDH 338

HSP 5 Score: 83.5741 bits (205), Expect = 2.141e-15
Identity = 51/180 (28.33%), Postives = 82/180 (45.56%), Query Frame = 1

Query:  310 HMRIQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLI----------------MASDIADTINDMGFDAEIFQFK----------EHTKDIIEVMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKLAPK--KTNKYNDH 765
             +RI GM C SCV  IE  + +L GV+S  ++L +   +V YDP                       + D     G D                 + T     + I GMTC+SCV++IE  ++Q++G+  + V+L        ++P +ISP ++  AIE+MGF+A +  +   TN   +H
Sbjct:  260 QLRIDGMHCKSCVLNIEENIGQLLGVQSIQVSLENKTAQVKYDPSCTSPVALQRAIEALPPGNFKVSLPDGAEGSGTDHRSSSSHSPGSPPRNQVQGTCSTTLIAIAGMTCASCVHSIEGMISQLEGVQQISVSLAEGTATVLYNPSVISPEELRAAIEDMGFEASVVSESCSTNPLGNH 439

HSP 6 Score: 58.151 bits (139), Expect = 1.236e-7
Identity = 26/72 (36.11%), Postives = 44/72 (61.11%), Query Frame = 1

Query:  541 VMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKLAPKKTNKY 756
            V I GMTC SCV +IE +++ ++GI+S+KV+L       K+ P ++  + +   I +MGF+A +A  K   +
Sbjct:   62 VRILGMTCQSCVKSIEDRISNLKGIISMKVSLEQGSATVKYVPSVVCLQQVCHQIGDMGFEASIAEGKAASW 133

[Close]

BLAST of Copper-transporting ATPase 1 vs. Ensembl Celegans
Match: cua-1 (CU (Copper) ATPase [Source:UniProtKB/TrEMBL;Acc:G5ED40])

HSP 1 Score: 715.687 bits (1846), Expect = 0.000e+0
Identity = 454/983 (46.19%), Postives = 625/983 (63.58%), Query Frame = 1

Query:  268 KNKETDNTKELFKCHMRIQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTI-NDMGFDAEIFQFKEHTKDI--IEVMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKLAPKKTN-KYNDHVGESIKKWKHSFLISLIFGVPTMIVMMVFMYGFSHRMQVIHLKNGINVTVMVSNAPIXXXXXXXXXXXXXXXXXPVQFYGARYFYVQAYKSIKHGSANMDVLVVMATSVSYIYSFIVILVSMILRQDSSPQTFFETTPMLIVFLSLGRWLEHIAKGKTSEALSKLLSLQAFEATIIVNDNQ-----ERKISXXXXXXXXXXXXXPGEKIPIDGRVVSGKSRCDESLITGESMSVEKIPGSDVIGGTLNISGMLIIRATLVGEDSALNQIVKLVEEAQTSKAPIQELADKVAGLFVPGVIICSMFTLLIWIAIGYT---NPNLLPGHSSINTDNTELIWKYAFQLAITVLSVACPCSLGLATPTAVMVGTGVGAINGILIKGGVPLEKMHQLDVIVFDKTGTITTGKPSVTNFVMCVENVTSQIRNCILLMLGAAESSSEHPIGKAILQYVRETCDINEMPQVVHSKSVSGFGLECSLK--LQSDMFVPDSEIDNVLVKINDFQENNL--TE-NLKETSVKWRKINEPVEVVLYLGNRNMMKENHISIPDKLDELMSRDEDNGRTVVLMAIDKVLLAMISIADQVKKEAALVVYTLEKMGVEVFLLTGDNHKTATAIAKEIGIRNVFAEVLPSHKVAKIQQIQNMSKYKRSWLFSCCSKPSKLTNVAMVGDGINDSPALAQADVGIAIGTGTDVAVEAADVVLIRNSLLDVIAAMKLSKDTVRRIRQNFVAATMYNLIGIPIAAGALMPIGVVFMPWMASVAMAASSICVVCXXXXXXXXXXPNEDQLANQEFKNHLECLKYGDMEVGVNLGKD 3165
            K  +  ++  L KC   ++GMTC+SCV  IE  + K++GV S ++ L++   EV YD  +  +  I + +  ++G+ A +        +   I ++I  ++  S    IES +    GI S  V++ T     +F PQ+I PRDI++ +E +GF A LA +    K  DH  + +KKW+++F I+LIFGVP MI+M++F +     M                  PI  P LSL+N LL    +PVQ +G RYFYV ++K+IKHG+ANMDVL++++T+++Y YS +V+L+++I +  SSP TFF+  PMLIVF++LGR LEH AKGKTSEALSKL+SLQA EAT++  D++     E+ I+++LV++ DL+KV+PG K+P+DG VV GKS  DES ITGESM V K PGS VIGG++N  G+LI++AT VG DS L+QIV+LVEEAQT++APIQ+LADK+AG FVP VI+ S+FTL +WI I Y    N NL PG         E   K AF+ AITVL++ACPCSLGLATPTAVMVGTGVGA NGILIKGG PLE +H++  IVFDKTGTIT G+P V      V   T  ++  I  + GA E+ SEHPIG A+  + ++  +    P        +G G+ C +    QS   +  S     + ++ D Q   +  TE NL + S K      P    + +G   MM+ + I + + +   +S ++  G   V+ AI+  ++A+ISIADQVKKEA+L +YTL +MG+ V LLTGDN KTA + AK++GI  VFAEVLP+ K  KI+Q++    YK                VAMVGDG+NDSPALA+A+VGIAI  G+DVA+E+A +VL+RN L+DV+ A+KLSK T RRIR NF+ A +YN IGIPIAAG   P G +  PWMA+ AMA SS+ VV  SLLLK ++KP    L    FK H + L+ G  +V V+ G D
Sbjct:  117 KYSKEGSSDHLEKCTFAVEGMTCASCVQYIERNISKIEGVHSIVVALIAAKAEVIYDGRVTSSDAIREHMTGELGYKATLLDSMGANPNYSKIRLIIGNLSTESDANRIESHVLSKSGIDSCNVSIATSMALVEFSPQVIGPRDIINVVESLGFTADLATRDDQMKRLDH-SDDVKKWRNTFFIALIFGVPVMIIMIIFHWILRTPMHPDK------------QTPIFTPALSLDNFLLLCLCTPVQIFGGRYFYVASWKAIKHGNANMDVLIMLSTTIAYTYSIVVLLLAIIFKWPSSPMTFFDVPPMLIVFIALGRMLEHKAKGKTSEALSKLMSLQAKEATLVTMDSEGRLTSEKGINIELVQRNDLIKVVPGAKVPVDGVVVDGKSSVDESFITGESMPVVKKPGSTVIGGSVNQKGVLIVKATHVGNDSTLSQIVRLVEEAQTNRAPIQQLADKIAGYFVPFVIVLSLFTLGVWIYIEYNSARNANLPPGL------RFEEALKIAFEAAITVLAIACPCSLGLATPTAVMVGTGVGAANGILIKGGEPLESVHKVTTIVFDKTGTITEGRPRVVQIASFVNPSTMSLK-LITFLSGATEALSEHPIGNAVAAFAKQLLNEPTWPNTSRFHVSAGHGVTCRIDSIRQSFSSLALSGSTCEIPRLPDGQTITIPGTEVNLLQVSSKEVSQPNPDTANIVIGTERMMERHGIPVSEVVKMTLSEEQRKGHISVICAINAEVVAVISIADQVKKEASLAIYTLREMGLRVVLLTGDNSKTAESTAKQVGIDEVFAEVLPNQKQQKIKQLKG---YK--------------NKVAMVGDGVNDSPALAEANVGIAIAAGSDVAIESAGIVLVRNDLVDVVGAIKLSKMTTRRIRLNFLFAIIYNAIGIPIAAGVFRPFGFMLQPWMAAAAMALSSVSVVSSSLLLKNFRKPTIANLYTTSFKRHQKFLESGSFQVQVHRGLD 1062

HSP 2 Score: 68.9366 bits (167), Expect = 2.141e-11
Identity = 47/183 (25.68%), Postives = 84/183 (45.90%), Query Frame = 1

Query:  319 IQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMGFDAEIFQ-----------------------------------------FKEHTKDIIE---VMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIE-EMGFDAKL 732
            I+GMTC +CV+ I++ V    G+   +++L    G V Y+ +      +A++I+DMGFD ++                                            KE + D +E     ++GMTC+SCV  IE  +++++G+ S+ VAL   K +  +D ++ S   I + +  E+G+ A L
Sbjct:   14 IEGMTCHACVNNIQDTVGSKDGIVKIVVSLEQKQGTVDYNSEKWNGESVAESIDDMGFDCKLITDQEIAAVEPQKASTTKLSISPLKTVDLSDGKVELQLNGVKYSKEGSSDHLEKCTFAVEGMTCASCVQYIERNISKIEGVHSIVVALIAAKAEVIYDGRVTSSDAIREHMTGELGYKATL 196

[Close]

BLAST of Copper-transporting ATPase 1 vs. Ensembl Celegans
Match: cua-1 (CU (Copper) ATPase [Source:UniProtKB/TrEMBL;Acc:G5ED40])

HSP 1 Score: 714.531 bits (1843), Expect = 0.000e+0
Identity = 454/983 (46.19%), Postives = 625/983 (63.58%), Query Frame = 1

Query:  268 KNKETDNTKELFKCHMRIQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTI-NDMGFDAEIFQFKEHTKDI--IEVMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKLAPKKTN-KYNDHVGESIKKWKHSFLISLIFGVPTMIVMMVFMYGFSHRMQVIHLKNGINVTVMVSNAPIXXXXXXXXXXXXXXXXXPVQFYGARYFYVQAYKSIKHGSANMDVLVVMATSVSYIYSFIVILVSMILRQDSSPQTFFETTPMLIVFLSLGRWLEHIAKGKTSEALSKLLSLQAFEATIIVNDNQ-----ERKISXXXXXXXXXXXXXPGEKIPIDGRVVSGKSRCDESLITGESMSVEKIPGSDVIGGTLNISGMLIIRATLVGEDSALNQIVKLVEEAQTSKAPIQELADKVAGLFVPGVIICSMFTLLIWIAIGYT---NPNLLPGHSSINTDNTELIWKYAFQLAITVLSVACPCSLGLATPTAVMVGTGVGAINGILIKGGVPLEKMHQLDVIVFDKTGTITTGKPSVTNFVMCVENVTSQIRNCILLMLGAAESSSEHPIGKAILQYVRETCDINEMPQVVHSKSVSGFGLECSLK--LQSDMFVPDSEIDNVLVKINDFQENNL--TE-NLKETSVKWRKINEPVEVVLYLGNRNMMKENHISIPDKLDELMSRDEDNGRTVVLMAIDKVLLAMISIADQVKKEAALVVYTLEKMGVEVFLLTGDNHKTATAIAKEIGIRNVFAEVLPSHKVAKIQQIQNMSKYKRSWLFSCCSKPSKLTNVAMVGDGINDSPALAQADVGIAIGTGTDVAVEAADVVLIRNSLLDVIAAMKLSKDTVRRIRQNFVAATMYNLIGIPIAAGALMPIGVVFMPWMASVAMAASSICVVCXXXXXXXXXXPNEDQLANQEFKNHLECLKYGDMEVGVNLGKD 3165
            K  +  ++  L KC   ++GMTC+SCV  IE  + K++GV S ++ L++   EV YD  +  +  I + +  ++G+ A +        +   I ++I  ++  S    IES +    GI S  V++ T     +F PQ+I PRDI++ +E +GF A LA +    K  DH  + +KKW+++F I+LIFGVP MI+M++F +     M                  PI  P LSL+N LL    +PVQ +G RYFYV ++K+IKHG+ANMDVL++++T+++Y YS +V+L+++I +  SSP TFF+  PMLIVF++LGR LEH AKGKTSEALSKL+SLQA EAT++  D++     E+ I+++LV++ DL+KV+PG K+P+DG VV GKS  DES ITGESM V K PGS VIGG++N  G+LI++AT VG DS L+QIV+LVEEAQT++APIQ+LADK+AG FVP VI+ S+FTL +WI I Y    N NL PG         E   K AF+ AITVL++ACPCSLGLATPTAVMVGTGVGA NGILIKGG PLE +H++  IVFDKTGTIT G+P V      V   T  ++  I  + GA E+ SEHPIG A+  + ++  +    P        +G G+ C +    QS   +  S     + ++ D Q   +  TE NL + S K      P    + +G   MM+ + I + + +   +S ++  G   V+ AI+  ++A+ISIADQVKKEA+L +YTL +MG+ V LLTGDN KTA + AK++GI  VFAEVLP+ K  KI+Q++    YK                VAMVGDG+NDSPALA+A+VGIAI  G+DVA+E+A +VL+RN L+DV+ A+KLSK T RRIR NF+ A +YN IGIPIAAG   P G +  PWMA+ AMA SS+ VV  SLLLK ++KP    L    FK H + L+ G  +V V+ G D
Sbjct:  239 KYSKEGSSDHLEKCTFAVEGMTCASCVQYIERNISKIEGVHSIVVALIAAKAEVIYDGRVTSSDAIREHMTGELGYKATLLDSMGANPNYSKIRLIIGNLSTESDANRIESHVLSKSGIDSCNVSIATSMALVEFSPQVIGPRDIINVVESLGFTADLATRDDQMKRLDH-SDDVKKWRNTFFIALIFGVPVMIIMIIFHWILRTPMHPDK------------QTPIFTPALSLDNFLLLCLCTPVQIFGGRYFYVASWKAIKHGNANMDVLIMLSTTIAYTYSIVVLLLAIIFKWPSSPMTFFDVPPMLIVFIALGRMLEHKAKGKTSEALSKLMSLQAKEATLVTMDSEGRLTSEKGINIELVQRNDLIKVVPGAKVPVDGVVVDGKSSVDESFITGESMPVVKKPGSTVIGGSVNQKGVLIVKATHVGNDSTLSQIVRLVEEAQTNRAPIQQLADKIAGYFVPFVIVLSLFTLGVWIYIEYNSARNANLPPGL------RFEEALKIAFEAAITVLAIACPCSLGLATPTAVMVGTGVGAANGILIKGGEPLESVHKVTTIVFDKTGTITEGRPRVVQIASFVNPSTMSLK-LITFLSGATEALSEHPIGNAVAAFAKQLLNEPTWPNTSRFHVSAGHGVTCRIDSIRQSFSSLALSGSTCEIPRLPDGQTITIPGTEVNLLQVSSKEVSQPNPDTANIVIGTERMMERHGIPVSEVVKMTLSEEQRKGHISVICAINAEVVAVISIADQVKKEASLAIYTLREMGLRVVLLTGDNSKTAESTAKQVGIDEVFAEVLPNQKQQKIKQLKG---YK--------------NKVAMVGDGVNDSPALAEANVGIAIAAGSDVAIESAGIVLVRNDLVDVVGAIKLSKMTTRRIRLNFLFAIIYNAIGIPIAAGVFRPFGFMLQPWMAAAAMALSSVSVVSSSLLLKNFRKPTIANLYTTSFKRHQKFLESGSFQVQVHRGLD 1184

HSP 2 Score: 86.2705 bits (212), Expect = 1.171e-16
Identity = 45/148 (30.41%), Postives = 82/148 (55.41%), Query Frame = 1

Query:  313 MRIQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMGFDAEIFQFKEHTKDIIE--------VMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKL 732
            + I+GMTC+SCV  I++ +    G+ S  +NL     + ++D     A  +A+ ++DMGFD ++ + KE    + E        V I+GMTC +CV  I+  +    GI+ + V+L  ++G   ++ +  +   + ++I++MGFD KL
Sbjct:   51 LEIKGMTCNSCVKNIQDVIGAKPGIHSIQVNLKEENAKCSFDTTKWTAEKVAEAVDDMGFDCKVLK-KEPPTQMAEKPKIRRAIVSIEGMTCHACVNNIQDTVGSKDGIVKIVVSLEQKQGTVDYNSEKWNGESVAESIDDMGFDCKL 197

HSP 3 Score: 77.0258 bits (188), Expect = 7.961e-14
Identity = 60/257 (23.35%), Postives = 114/257 (44.36%), Query Frame = 1

Query:  112 LKIIEDFFQFNDNIKTVVIDYEKNLVRICCHNDNCTYLTLCEAIENLGFLINKNKETDNTKELFKCHMR-----IQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMGFDAEIFQ-----------------------------------------FKEHTKDIIE---VMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIE-EMGFDAKL 732
            +K I+D       I ++ ++ ++   +        T   + EA++++GF     K+   T+   K  +R     I+GMTC +CV+ I++ V    G+   +++L    G V Y+ +      +A++I+DMGFD ++                                            KE + D +E     ++GMTC+SCV  IE  +++++G+ S+ VAL   K +  +D ++ S   I + +  E+G+ A L
Sbjct:   62 VKNIQDVIGAKPGIHSIQVNLKEENAKCSFDTTKWTAEKVAEAVDDMGFDCKVLKKEPPTQMAEKPKIRRAIVSIEGMTCHACVNNIQDTVGSKDGIVKIVVSLEQKQGTVDYNSEKWNGESVAESIDDMGFDCKLITDQEIAAVEPQKASTTKLSISPLKTVDLSDGKVELQLNGVKYSKEGSSDHLEKCTFAVEGMTCASCVQYIERNISKIEGVHSIVVALIAAKAEVIYDGRVTSSDAIREHMTGELGYKATL 318

HSP 4 Score: 52.373 bits (124), Expect = 2.144e-6
Identity = 25/66 (37.88%), Postives = 39/66 (59.09%), Query Frame = 1

Query:  547 IQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKLAPKK 744
            I+GMTC+SCV  I+  +    GI S++V L  E  K  FD    +   + +A+++MGFD K+  K+
Sbjct:   53 IKGMTCNSCVKNIQDVIGAKPGIHSIQVNLKEENAKCSFDTTKWTAEKVAEAVDDMGFDCKVLKKE 118

[Close]

BLAST of Copper-transporting ATPase 1 vs. Ensembl Celegans
Match: catp-1 (Cation transporting ATPase [Source:UniProtKB/TrEMBL;Acc:G5EBE7])

HSP 1 Score: 78.5666 bits (192), Expect = 2.100e-14
Identity = 54/175 (30.86%), Postives = 93/175 (53.14%), Query Frame = 1

Query: 2437 DKVLLAMISIADQVKKEAALVVYTLEKMGVEVFLLTGDNHKTATAIAKEIGIRNVFAEVLPSHKVAKIQQIQN---------MSKYKRS-W---------LFSCCSKPSKL----------TNVAMVGDGINDSPALAQADVGIAIG-TGTDVAVEAADVVLIRNSLLDVIAAMK 2871
            D V L M +I D  + E A  +   +  GV+VF++TGD+  TATAIA++IG+      +  S  +  +++ QN         +  YK+S W         +F+  +   KL            VA+ G G++D+P LA A+VGIA+G +G+D+A + AD+VL+ ++   ++  ++
Sbjct:  694 DLVFLGMAAIMDPPRPETAAAIEQCKMAGVKVFMITGDHPTTATAIARQIGL------IGSSTNLNDVEKPQNSWAVVTGDQLKNYKKSDWNLLLKNHNIVFARTNTEQKLEIVQEVQRRGETVAVTGGGVDDTPVLAHANVGIAMGQSGSDIAKQTADIVLLDDNFASIVMGIE 862

[Close]

BLAST of Copper-transporting ATPase 1 vs. Ensembl Celegans
Match: catp-1 (Cation transporting ATPase [Source:UniProtKB/TrEMBL;Acc:G5EBE7])

HSP 1 Score: 78.1814 bits (191), Expect = 3.041e-14
Identity = 54/175 (30.86%), Postives = 93/175 (53.14%), Query Frame = 1

Query: 2437 DKVLLAMISIADQVKKEAALVVYTLEKMGVEVFLLTGDNHKTATAIAKEIGIRNVFAEVLPSHKVAKIQQIQN---------MSKYKRS-W---------LFSCCSKPSKL----------TNVAMVGDGINDSPALAQADVGIAIG-TGTDVAVEAADVVLIRNSLLDVIAAMK 2871
            D V L M +I D  + E A  +   +  GV+VF++TGD+  TATAIA++IG+      +  S  +  +++ QN         +  YK+S W         +F+  +   KL            VA+ G G++D+P LA A+VGIA+G +G+D+A + AD+VL+ ++   ++  ++
Sbjct:  694 DLVFLGMAAIMDPPRPETAAAIEQCKMAGVKVFMITGDHPTTATAIARQIGL------IGSSTNLNDVEKPQNSWAVVTGDQLKNYKKSDWNLLLKNHNIVFARTNTEQKLEIVQEVQRRGETVAVTGGGVDDTPVLAHANVGIAMGQSGSDIAKQTADIVLLDDNFASIVMGIE 862

[Close]

BLAST of Copper-transporting ATPase 1 vs. Ensembl Celegans
Match: sca-1 (Calcium-transporting ATPase [Source:UniProtKB/TrEMBL;Acc:Q9XU13])

HSP 1 Score: 78.1814 bits (191), Expect = 3.086e-14
Identity = 72/309 (23.30%), Postives = 144/309 (46.60%), Query Frame = 1

Query: 2137 KSVSGFGLECSLKLQSDMFVPDSEIDNVLVKINDFQENNLTENLKETSVKWRKINEPVEVVLYLGNRNMMKENHISIPDKLDELMSRDEDNGRTVVLMAIDKVLLAMISIADQVKKEAALVVYTLEKMGVEVFLLTGDNHKTATAIAKEIGI----RNVFAEVLPSHKVAKIQQIQNMSKYKRSWLFSCC--SKPSKLTNV--------AMVGDGINDSPALAQADVGIAIGTGTDVAVEAADVVLIRNSLLDVIAAMKLSKDTVRRIRQ-----------NFVAATMYNLIGIPIAAGALMPIGVVFM 2988
            KS+S +    S    + MFV  +  + VL +    + N   + +  TS   +KI +  + V Y   R+ ++   +   D    + + + ++    V    D   + ++ + D  + E +  +      G+ V ++TGDN  TA AI + IG+     +   +     +   +   Q     +R+ LF+    S  SK+ ++        AM GDG+ND+PAL +A++GI++G+GT VA  A+++VL  ++   +++A++  +     ++Q             V+  M   +GIP    AL+P+ ++++
Sbjct:  369 KSMSAYCFPASGGSGAKMFVKGAP-EGVLGRCTHVRVNG--QKVPLTSAMTQKIVD--QCVQYGTGRDTLRCLALGTIDTPVSVSNMNLEDSTQFVKYEQDITFVGVVGMLDPPRTEVSDSIKACNHAGIRVIMITGDNKNTAEAIGRRIGLFGENEDTTGKAYTGREFDDLPPEQQSEACRRAKLFARVEPSHKSKIVDILQSQGEITAMTGDGVNDAPALKKAEIGISMGSGTAVAKSASEMVLADDNFASIVSAVEEGRAIYNNMKQFIRYLISSNVGEVVSIFMVAALGIP---EALIPVQLLWV 669

[Close]

BLAST of Copper-transporting ATPase 1 vs. Ensembl Fly
Match: ATP7 (gene:FBgn0030343 transcript:FBtr0334454)

HSP 1 Score: 790.03 bits (2039), Expect = 0.000e+0
Identity = 451/991 (45.51%), Postives = 640/991 (64.58%), Query Frame = 1

Query:  298 LFKCHMRIQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMGFDAEIFQFKEHTKDIIEVMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKL---APKKTNKYNDHVGESIKKWKHSFLISLIFGVPTMIVMMVFMYGFSHRMQVIHLKNGINVTVMVSNAPIXXXXXXXXXXXXXXXXXPVQFYGARYFYVQAYKSIKHGSANMDVLVVMATSVSYIYSFIVILVSMILRQDSSPQTFFETTPMLIVFLSLGRWLEHIAKGKTSEALSKLLSLQAFEATII-----VNDNQERKISXXXXXXXXXXXXXPGEKIPIDGRVVSGKSRCDESLITGESMSVEKIPGSDVIGGTLNISGMLIIRATLVGEDSALNQIVKLVEEAQTSKAPIQELADKVAGLFVPGVIICSMFTLLIWIAIGYTNPNLLP--GHSSINTDNTELIWKYAFQLAITVLSVACPCSLGLATPTAVMVGTGVGAINGILIKGGVPLEKMHQLDVIVFDKTGTITTGKPSVTNFVMCV-ENVTSQIRNCILLMLGAAESSSEHPIGKAILQYVRETCDINEMPQV------VHSKSVSGFGLECSLKLQSDMFVPDSEIDNVLVKINDFQEN-----------NLTENLKETSVKW------------------------RKINEPVEVVLYLGNRNMMKENHISIPDKLDELMSRDEDNGRTVVLMAIDKVLLAMISIADQVKKEAALVVYTLEKMGVEVFLLTGDNHKTATAIAKEIGIRNVFAEVLPSHKVAKIQQIQNMSKYKRSWLFSCCSKPSKLTNVAMVGDGINDSPALAQADVGIAIGTGTDVAVEAADVVLIRNSLLDVIAAMKLSKDTVRRIRQNFVAATMYNLIGIPIAAGALMPIGVVFMPWMASVAMAASSICVVCXXXXXXXXXXPNEDQLANQEFKNHL 3114
            L KC + I+GMTC+SCV  IE    K+ G+ S L+ LL+   EV ++ +++ A +IA +I ++GF  E+    ++ +  +E+ I GMTC+SCV  IES + +++G+ +  V L T++GKF++  +   PR I +AIE +GF+AKL     K  + Y +H  E I+KW+++FL+SLIFG P M+ M+ FM   S        K   N+  +V    +    + L +        PVQF+G  +FYVQ+Y++IKHG+ NMDVL+ M T++SY+YS  V++ +++L Q+SSP TFF+T PML++F+SLGRWLEHIAKGKTSEALSKLLSL+A +A ++      +   E+ ISVD V++GD++KV+PG K+P+DG+V+ G S CDESLITGESM V K  GS VIGG++N +G+L++ AT  GE++ L QIV+LVEEAQTSKAPIQ+LAD++AG FVP V++ S  TL+ WI IG++NPNL+P      ++ D   +I  YAF+ A++VL++ACPC+LGLATPTAVMV TG GAING+L+KG   LE  H++  +VFDKTGTIT G P  +   + V   V S  R   L ++GAAE +SEHPI  AI+ + ++  ++   PQ        H ++V G G+  ++             D ++   N  + +           ++   L + SV+                         +KI +  E+++ +GNR  M+ N I +P ++ + M+ +E  G T VL A++  L+ M +++D VK EA L VYTL++MG++V LLTGDN  TA +IA+E+GIR V+AEVLPSHKVAKIQ+IQ                 +    VAMVGDG+NDSPALAQADVGI I  GTDVA EA+D+VL+RN LLDV+A + LS+ TVRRIR NF  A+MYNL+GIP+A+G   P G   +PWMASVAMAASS+ VVC SLLLK+++KP    L   E++  L
Sbjct:  207 LTKCFLHIRGMTCASCVAAIEKHCKKIYGLDSILVALLAAKAEVKFNANVVTAENIAKSITELGFPTELIDEPDNGEAEVELEIMGMTCASCVNKIESHVLKIRGVTTASVTLLTKRGKFRYITEETGPRSICEAIEALGFEAKLMTGRDKMAHNYLEH-KEEIRKWRNAFLVSLIFGGPCMVAMIYFMLEMSD-------KGHANMCCLVPGLSMENLVMFLLST-------PVQFFGGFHFYVQSYRAIKHGTTNMDVLISMVTTISYVYSVAVVIAAVLLEQNSSPLTFFDTPPMLLIFISLGRWLEHIAKGKTSEALSKLLSLKAADALLVEISPDFDIISEKVISVDYVQRGDILKVIPGAKVPVDGKVLYGHSSCDESLITGESMPVAKRKGSVVIGGSINQNGVLLVEATHTGENTTLAQIVRLVEEAQTSKAPIQQLADRIAGYFVPFVVVVSSITLIAWIIIGFSNPNLVPVAMEHKMHMDQNTIIVSYAFKCALSVLAIACPCALGLATPTAVMVATGTGAINGVLVKGATALENAHKVKTVVFDKTGTITHGTPMTSKVTLFVTAQVCSLAR--ALTIVGAAEQNSEHPIASAIVHFAKDMLNVGATPQAGSFGKSSHFQAVPGCGIRVTVSNYEQTLRQACNADRIINYENLHRTHPQGSVPVDNGASIEHLLPQRSVRKSMELNNQQLLSDLVLEPEEELLTDQKIIDSPEILVLIGNREWMERNAIEVPLEISDCMTHEERKGHTAVLCALNGQLVCMFAVSDMVKPEAHLAVYTLKRMGIDVVLLTGDNKNTAASIAREVGIRTVYAEVLPSHKVAKIQRIQ-----------------ANGIRVAMVGDGVNDSPALAQADVGITIAAGTDVAAEASDIVLMRNDLLDVVACLDLSRCTVRRIRYNFFFASMYNLLGIPLASGLFAPYGFTLLPWMASVAMAASSVSVVCSSLLLKMYRKPTAKTLRTAEYEAQL 1163

HSP 2 Score: 82.8037 bits (203), Expect = 1.355e-15
Identity = 47/149 (31.54%), Postives = 70/149 (46.98%), Query Frame = 1

Query:  310 HMRIQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMGFDAEIFQFKEHTKDIIE--------VMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKL 732
             + I GMTC SCV  I   + +  G+    + L    G   YDP     + IA  I+DMGF+     +     D  E        + + GMTC SCV  IE  +    GI S++V L  +  + ++DP    P  I + I++MGF+A +
Sbjct:   15 RLPIVGMTCQSCVRNITEHIGQKSGILGVRVILEENAGYFDYDPRQTDPARIASDIDDMGFEC---SYPGDAADPPETPASAWTNIRVVGMTCQSCVRNIEGNIGTKPGIHSIEVQLAAKNARVQYDPAQYDPAQIAELIDDMGFEASV 160

HSP 3 Score: 58.9214 bits (141), Expect = 3.154e-8
Identity = 28/69 (40.58%), Postives = 37/69 (53.62%), Query Frame = 1

Query:  517 EHTKDIIEVMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFD 723
            E T   + + I GMTC SCV  I   + Q  GIL V+V L    G F +DP+   P  I   I++MGF+
Sbjct:    8 EATMSTVRLPIVGMTCQSCVRNITEHIGQKSGILGVRVILEENAGYFDYDPRQTDPARIASDIDDMGFE 76

[Close]

BLAST of Copper-transporting ATPase 1 vs. Ensembl Fly
Match: ATP7 (gene:FBgn0030343 transcript:FBtr0273257)

HSP 1 Score: 790.03 bits (2039), Expect = 0.000e+0
Identity = 451/991 (45.51%), Postives = 640/991 (64.58%), Query Frame = 1

Query:  298 LFKCHMRIQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMGFDAEIFQFKEHTKDIIEVMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKL---APKKTNKYNDHVGESIKKWKHSFLISLIFGVPTMIVMMVFMYGFSHRMQVIHLKNGINVTVMVSNAPIXXXXXXXXXXXXXXXXXPVQFYGARYFYVQAYKSIKHGSANMDVLVVMATSVSYIYSFIVILVSMILRQDSSPQTFFETTPMLIVFLSLGRWLEHIAKGKTSEALSKLLSLQAFEATII-----VNDNQERKISXXXXXXXXXXXXXPGEKIPIDGRVVSGKSRCDESLITGESMSVEKIPGSDVIGGTLNISGMLIIRATLVGEDSALNQIVKLVEEAQTSKAPIQELADKVAGLFVPGVIICSMFTLLIWIAIGYTNPNLLP--GHSSINTDNTELIWKYAFQLAITVLSVACPCSLGLATPTAVMVGTGVGAINGILIKGGVPLEKMHQLDVIVFDKTGTITTGKPSVTNFVMCV-ENVTSQIRNCILLMLGAAESSSEHPIGKAILQYVRETCDINEMPQV------VHSKSVSGFGLECSLKLQSDMFVPDSEIDNVLVKINDFQEN-----------NLTENLKETSVKW------------------------RKINEPVEVVLYLGNRNMMKENHISIPDKLDELMSRDEDNGRTVVLMAIDKVLLAMISIADQVKKEAALVVYTLEKMGVEVFLLTGDNHKTATAIAKEIGIRNVFAEVLPSHKVAKIQQIQNMSKYKRSWLFSCCSKPSKLTNVAMVGDGINDSPALAQADVGIAIGTGTDVAVEAADVVLIRNSLLDVIAAMKLSKDTVRRIRQNFVAATMYNLIGIPIAAGALMPIGVVFMPWMASVAMAASSICVVCXXXXXXXXXXPNEDQLANQEFKNHL 3114
            L KC + I+GMTC+SCV  IE    K+ G+ S L+ LL+   EV ++ +++ A +IA +I ++GF  E+    ++ +  +E+ I GMTC+SCV  IES + +++G+ +  V L T++GKF++  +   PR I +AIE +GF+AKL     K  + Y +H  E I+KW+++FL+SLIFG P M+ M+ FM   S        K   N+  +V    +    + L +        PVQF+G  +FYVQ+Y++IKHG+ NMDVL+ M T++SY+YS  V++ +++L Q+SSP TFF+T PML++F+SLGRWLEHIAKGKTSEALSKLLSL+A +A ++      +   E+ ISVD V++GD++KV+PG K+P+DG+V+ G S CDESLITGESM V K  GS VIGG++N +G+L++ AT  GE++ L QIV+LVEEAQTSKAPIQ+LAD++AG FVP V++ S  TL+ WI IG++NPNL+P      ++ D   +I  YAF+ A++VL++ACPC+LGLATPTAVMV TG GAING+L+KG   LE  H++  +VFDKTGTIT G P  +   + V   V S  R   L ++GAAE +SEHPI  AI+ + ++  ++   PQ        H ++V G G+  ++             D ++   N  + +           ++   L + SV+                         +KI +  E+++ +GNR  M+ N I +P ++ + M+ +E  G T VL A++  L+ M +++D VK EA L VYTL++MG++V LLTGDN  TA +IA+E+GIR V+AEVLPSHKVAKIQ+IQ                 +    VAMVGDG+NDSPALAQADVGI I  GTDVA EA+D+VL+RN LLDV+A + LS+ TVRRIR NF  A+MYNL+GIP+A+G   P G   +PWMASVAMAASS+ VVC SLLLK+++KP    L   E++  L
Sbjct:  207 LTKCFLHIRGMTCASCVAAIEKHCKKIYGLDSILVALLAAKAEVKFNANVVTAENIAKSITELGFPTELIDEPDNGEAEVELEIMGMTCASCVNKIESHVLKIRGVTTASVTLLTKRGKFRYITEETGPRSICEAIEALGFEAKLMTGRDKMAHNYLEH-KEEIRKWRNAFLVSLIFGGPCMVAMIYFMLEMSD-------KGHANMCCLVPGLSMENLVMFLLST-------PVQFFGGFHFYVQSYRAIKHGTTNMDVLISMVTTISYVYSVAVVIAAVLLEQNSSPLTFFDTPPMLLIFISLGRWLEHIAKGKTSEALSKLLSLKAADALLVEISPDFDIISEKVISVDYVQRGDILKVIPGAKVPVDGKVLYGHSSCDESLITGESMPVAKRKGSVVIGGSINQNGVLLVEATHTGENTTLAQIVRLVEEAQTSKAPIQQLADRIAGYFVPFVVVVSSITLIAWIIIGFSNPNLVPVAMEHKMHMDQNTIIVSYAFKCALSVLAIACPCALGLATPTAVMVATGTGAINGVLVKGATALENAHKVKTVVFDKTGTITHGTPMTSKVTLFVTAQVCSLAR--ALTIVGAAEQNSEHPIASAIVHFAKDMLNVGATPQAGSFGKSSHFQAVPGCGIRVTVSNYEQTLRQACNADRIINYENLHRTHPQGSVPVDNGASIEHLLPQRSVRKSMELNNQQLLSDLVLEPEEELLTDQKIIDSPEILVLIGNREWMERNAIEVPLEISDCMTHEERKGHTAVLCALNGQLVCMFAVSDMVKPEAHLAVYTLKRMGIDVVLLTGDNKNTAASIAREVGIRTVYAEVLPSHKVAKIQRIQ-----------------ANGIRVAMVGDGVNDSPALAQADVGITIAAGTDVAAEASDIVLMRNDLLDVVACLDLSRCTVRRIRYNFFFASMYNLLGIPLASGLFAPYGFTLLPWMASVAMAASSVSVVCSSLLLKMYRKPTAKTLRTAEYEAQL 1163

HSP 2 Score: 82.8037 bits (203), Expect = 1.355e-15
Identity = 47/149 (31.54%), Postives = 70/149 (46.98%), Query Frame = 1

Query:  310 HMRIQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMGFDAEIFQFKEHTKDIIE--------VMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKL 732
             + I GMTC SCV  I   + +  G+    + L    G   YDP     + IA  I+DMGF+     +     D  E        + + GMTC SCV  IE  +    GI S++V L  +  + ++DP    P  I + I++MGF+A +
Sbjct:   15 RLPIVGMTCQSCVRNITEHIGQKSGILGVRVILEENAGYFDYDPRQTDPARIASDIDDMGFEC---SYPGDAADPPETPASAWTNIRVVGMTCQSCVRNIEGNIGTKPGIHSIEVQLAAKNARVQYDPAQYDPAQIAELIDDMGFEASV 160

HSP 3 Score: 58.9214 bits (141), Expect = 3.154e-8
Identity = 28/69 (40.58%), Postives = 37/69 (53.62%), Query Frame = 1

Query:  517 EHTKDIIEVMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFD 723
            E T   + + I GMTC SCV  I   + Q  GIL V+V L    G F +DP+   P  I   I++MGF+
Sbjct:    8 EATMSTVRLPIVGMTCQSCVRNITEHIGQKSGILGVRVILEENAGYFDYDPRQTDPARIASDIDDMGFE 76

[Close]

BLAST of Copper-transporting ATPase 1 vs. Ensembl Fly
Match: SPoCk (gene:FBgn0052451 transcript:FBtr0078531)

HSP 1 Score: 77.411 bits (189), Expect = 6.088e-14
Identity = 57/170 (33.53%), Postives = 85/170 (50.00%), Query Frame = 1

Query: 2437 DKVLLAMISIADQVKKEAALVVYTLEKMGVEVFLLTGDNHKTATAIAKEIGIRNVFAEVLPSHKVAKIQQIQNMSKYKRSWLFSCCSKPSKL----------TNVAMVGDGINDSPALAQADVGIAIG-TGTDVAVEAADVVLIRNSLLDVIAAMKLSKDTVRRIRQNFV 2913
            D +   ++ I D  +      +  L + GV V ++TGD  +TA AIA  IGI  +  + L   ++ ++ + Q         +F   S   KL            V M GDG+ND  AL +AD+GIA+G  GTDV  EAAD++L+ +    +IAA++  K     IR NFV
Sbjct:  518 DLIYCGLVGITDPPRPLVRESIEMLMQSGVRVKMVTGDAQETALAIANLIGIDTIHHQTLSGQEMDQMNEHQLDKVANNVSVFYRVSPRHKLEIVKSLQRSGNIVGMTGDGVNDGVALKKADIGIAMGKNGTDVCKEAADMILVNDDFHTIIAAIEEGKGIFYNIR-NFV 686

[Close]

BLAST of Copper-transporting ATPase 1 vs. Ensembl Fly
Match: SPoCk (gene:FBgn0052451 transcript:FBtr0306600)

HSP 1 Score: 77.411 bits (189), Expect = 6.470e-14
Identity = 57/170 (33.53%), Postives = 85/170 (50.00%), Query Frame = 1

Query: 2437 DKVLLAMISIADQVKKEAALVVYTLEKMGVEVFLLTGDNHKTATAIAKEIGIRNVFAEVLPSHKVAKIQQIQNMSKYKRSWLFSCCSKPSKL----------TNVAMVGDGINDSPALAQADVGIAIG-TGTDVAVEAADVVLIRNSLLDVIAAMKLSKDTVRRIRQNFV 2913
            D +   ++ I D  +      +  L + GV V ++TGD  +TA AIA  IGI  +  + L   ++ ++ + Q         +F   S   KL            V M GDG+ND  AL +AD+GIA+G  GTDV  EAAD++L+ +    +IAA++  K     IR NFV
Sbjct:  534 DLIYCGLVGITDPPRPLVRESIEMLMQSGVRVKMVTGDAQETALAIANLIGIDTIHHQTLSGQEMDQMNEHQLDKVANNVSVFYRVSPRHKLEIVKSLQRSGNIVGMTGDGVNDGVALKKADIGIAMGKNGTDVCKEAADMILVNDDFHTIIAAIEEGKGIFYNIR-NFV 702

[Close]

BLAST of Copper-transporting ATPase 1 vs. Ensembl Fly
Match: SPoCk (gene:FBgn0052451 transcript:FBtr0302134)

HSP 1 Score: 77.411 bits (189), Expect = 6.470e-14
Identity = 57/170 (33.53%), Postives = 85/170 (50.00%), Query Frame = 1

Query: 2437 DKVLLAMISIADQVKKEAALVVYTLEKMGVEVFLLTGDNHKTATAIAKEIGIRNVFAEVLPSHKVAKIQQIQNMSKYKRSWLFSCCSKPSKL----------TNVAMVGDGINDSPALAQADVGIAIG-TGTDVAVEAADVVLIRNSLLDVIAAMKLSKDTVRRIRQNFV 2913
            D +   ++ I D  +      +  L + GV V ++TGD  +TA AIA  IGI  +  + L   ++ ++ + Q         +F   S   KL            V M GDG+ND  AL +AD+GIA+G  GTDV  EAAD++L+ +    +IAA++  K     IR NFV
Sbjct:  534 DLIYCGLVGITDPPRPLVRESIEMLMQSGVRVKMVTGDAQETALAIANLIGIDTIHHQTLSGQEMDQMNEHQLDKVANNVSVFYRVSPRHKLEIVKSLQRSGNIVGMTGDGVNDGVALKKADIGIAMGKNGTDVCKEAADMILVNDDFHTIIAAIEEGKGIFYNIR-NFV 702

[Close]

BLAST of Copper-transporting ATPase 1 vs. Ensembl Zebrafish
Match: atp7a (ATPase copper transporting alpha [Source:ZFIN;Acc:ZDB-GENE-060825-45])

HSP 1 Score: 825.469 bits (2131), Expect = 0.000e+0
Identity = 455/932 (48.82%), Postives = 613/932 (65.77%), Query Frame = 1

Query:  286 NTKELFKCHMRIQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMGFDAEIFQFKEHTKDIIEVMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKLAPK-KTNKYNDHVGESIKKWKHSFLISLIFGVPTMIVMMVFMYGFSHRMQVIHLKNGINVTVMVSNAPIXXXXXXXXXXXXXXXX------XPVQFYGARYFYVQAYKSIKHGSANMDVLVVMATSVSYIYSFIVILVSMILRQDSSPQTFFETTPMLIVFLSLGRWLEHIAKGKTSEALSKLLSLQAFEATII-VNDN----QERKISXXXXXXXXXXXXXPGEKIPIDGRVVSGKSRCDESLITGESMSVEKIPGSDVIGGTLNISGMLIIRATLVGEDSALNQIVKLVEEAQTSKAPIQELADKVAGLFVPGVIICSMFTLLIWIAIGYTNPNLL----PGHSSINTDNTELIWKYAFQLAITVLSVACPCSLGLATPTAVMVGTGVGAINGILIKGGVPLEKMHQLDVIVFDKTGTITTGKPSVTNFVMCVENVTSQIRNCILLMLGAAESSSEHPIGKAILQYVRETCDINEMPQVVHSKSVSGFGLEC------SLKLQSDMFVPDSEIDNVLVKINDFQENNLTENLKETSVKWRKINEPVEVVLYLGNRNMMKENHISIPDKLDELMSRDEDNGRTVVLMAIDKVLLAMISIADQVKKEAALVVYTLEKMGVEVFLLTGDNHKTATAIAKEIGIRNVFAEVLPSHKVAKIQQIQNMSKYKRSWLFSCCSKPSKLTNVAMVGDGINDSPALAQADVGIAIGTGTDVAVEAADVVLIRNSLLDVIAAMKLSKDTVRRIRQNFVAATMYNLIGIPIAAGALMPIGVVFMPWMASVAMA 3015
            +T  + KC ++I GMTC+SCV  IE  +    G+ S L+ L+++  EV Y P +I    IA+ I ++GF A +    + +   +E++++GMTC+SCV+ IES L + +GIL   VAL+T K   K+DP++  PRDI+  IE MGF A L  K +   + DH  E I++WK SF ISL F VP M  MM++M    H +   H  +             +F    L   L  +         PVQF G RYFY QAYK++KH +ANMDVL+V+AT++++ YS +V+LV+M+ R   +P TFF+T PML VF+SLGRWLE IAK KTSEALSKL+SLQA EAT++ +N++     E ++ V+LV++GD+VKV+PG K P+DGRV+ G S  DESLITGE+M V K PGS VI G++N +G L+I+AT VG D+ L+QIVKLVEEAQTSKAPIQ+ ADK++  FVP +++ S+ TLL WI IG+ N +L+    PG+   +    E + ++AFQ +ITVL +ACPCSLGLATPTAVMVGTGVGA NGILIKGG PLE  H++  +VFDKTGTIT G P V    M  E      R+ +L ++G AE+SSEHP+G AI +Y ++      +      ++V G G+ C      +L  + D    +++ + VL++I+D + ++ TE+      +   + +     + +GNR  M+ N + +   +DE M+  E  G T VL+A+D  L AM++IAD VK EA L V+ L  MG+EV L+TGDN KTA AIA ++GIR VFAEVLPSHKVAK++Q+Q   K                  VAMVGDG+NDSPALA ADVGIAIGTGTDVA+EAADVVLIRN LLDV+ ++ LSK TV+RIR NFV A MYNL+GIPIAAG  MP+G+V  PWM S AMA
Sbjct:  468 STNTISKCFIQIGGMTCASCVANIERNLKNEYGIHSVLVALMASKAEVRYSPSVIDPLRIAELIRELGFTATVMDNYDGSDGSLELVVRGMTCASCVHKIESNLMKQKGILYASVALSTNKAHIKYDPEVTGPRDIIRLIENMGFTASLVKKDRPGSHLDHSRE-IRQWKRSFQISLFFCVPVM-GMMIYMIVVDHMIDKYHQHHNATAEDRAKYHSTMFLEKQLLPGLSIMNLISFLFCVPVQFIGGRYFYCQAYKAVKHRTANMDVLIVLATTIAFTYSVVVLLVAMVERAKVNPITFFDTPPMLFVFISLGRWLEQIAKSKTSEALSKLMSLQATEATVVTLNEDMSVLSEEQVDVELVQRGDVVKVVPGGKFPVDGRVIEGHSMADESLITGEAMPVTKKPGSTVIAGSINQNGSLLIKATHVGTDTTLSQIVKLVEEAQTSKAPIQQFADKISSYFVPFIVVISVLTLLAWIIIGFVNFSLVQTYFPGYDK-SISEAEAVIRFAFQASITVLCIACPCSLGLATPTAVMVGTGVGAQNGILIKGGEPLEMAHKIQSVVFDKTGTITYGAPKVVQVKMLAEG-NRLPRSKLLAIVGTAENSSEHPLGAAITKYCKQELGTESLGTCTDFQAVPGCGIRCLVSNTENLLKREDSDSEENQHNAVLIQISDARAHS-TEHPLIMDPQPLTVVQTASYTVLIGNREWMRRNALQVRADVDEAMTEHERRGCTAVLVAVDNELCAMVAIADTVKPEAELAVHVLSAMGLEVVLMTGDNSKTARAIAAQVGIRKVFAEVLPSHKVAKVEQLQQEGK-----------------RVAMVGDGVNDSPALAMADVGIAIGTGTDVAIEAADVVLIRNDLLDVVGSIDLSKKTVKRIRINFVFALMYNLVGIPIAAGVFMPVGLVLQPWMGSAAMA 1377

HSP 2 Score: 97.8265 bits (242), Expect = 4.911e-20
Identity = 52/148 (35.14%), Postives = 85/148 (57.43%), Query Frame = 1

Query:  313 MRIQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDM---GFDAEIFQ-----FKEHTKDIIEVMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKL 732
             ++ GM C+SCV  I++ + KL  V S +++L +    + ++P  + A ++   I  +    F A I       F +    + E+ I+GMTC SCV +IE  L+Q +G+ S +V+L   KG F++DP + SP ++  AIE+MGFDA L
Sbjct:  279 FQVTGMHCNSCVVNIQDNISKLPAVTSVVVSLENRQASIQHNPKQVSAVELQKAIEALPPGNFKAIIPASPEPGFLQPLVSVAEIHIEGMTCGSCVQSIEGTLSQKKGVRSAQVSLANHKGTFEYDPLLTSPEELRAAIEDMGFDAFL 426

HSP 3 Score: 94.7449 bits (234), Expect = 4.644e-19
Identity = 70/246 (28.46%), Postives = 105/246 (42.68%), Query Frame = 1

Query:  121 IEDFFQFNDNIKTVVIDYEKNLVRICCHNDNCTYLTLCEAIE-----NLGFLINKNKETDNTKELFK-CHMRIQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMGFDAEIFQFKEHTKDIIE--------------------------------------VMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDA 726
            I+D       + +VV+  E     I  +    + + L +AIE     N   +I  + E    + L     + I+GMTC SCV +IE  + + KGV+SA ++L +  G   YDP L    ++   I DMGFDA + +       +++                                      + I GMTC+SCV  IE  L    GI SV VAL   K + ++ P +I P  I + I E+GF A
Sbjct:  293 IQDNISKLPAVTSVVVSLENRQASIQHNPKQVSAVELQKAIEALPPGNFKAIIPASPEPGFLQPLVSVAEIHIEGMTCGSCVQSIEGTLSQKKGVRSAQVSLANHKGTFEYDPLLTSPEELRAAIEDMGFDAFLPETNSLVPSVVKSPSLSVRSSSLSPVRSAVKENEAESDAEPSTNTISKCFIQIGGMTCASCVANIERNLKNEYGIHSVLVALMASKAEVRYSPSVIDPLRIAELIRELGFTA 538

HSP 4 Score: 59.3066 bits (142), Expect = 3.309e-8
Identity = 40/153 (26.14%), Postives = 69/153 (45.10%), Query Frame = 1

Query:  298 LFKCHMRIQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMGFDAEIFQFKEHTKDIIEVMIQGMTCSS-CVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKLAPKKTNK 753
            L +  + ++GMTC SCV +IE ++  L GV    ++L      VTYD        IAD I DMGF++ +             +     CS+  V    S LAQ++G++  + +   +     F P ++S   + + ++ +  D    P  + K
Sbjct:    7 LCRVTLGVEGMTCGSCVQSIEGRIGGLPGVIHIQVSLEQNNATVTYDHTQHTPQSIADAIEDMGFESSLTNATSTPVQTETKVFSKAGCSADSVQQALSTLAQIKGVIETQESADNQGLAVTFVPSLVSEDQLGEVLKCLAPDTACRPPLSPK 159

HSP 5 Score: 55.0694 bits (131), Expect = 6.883e-7
Identity = 47/204 (23.04%), Postives = 96/204 (47.06%), Query Frame = 1

Query:  166 IDYEKNLVRICCHNDNCTYLTLCEAIENLGFLINKNKETDNTKELFKCHMRI-QGMTCSS-CVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMGFDAEI---FQFKEHTK-------DIIEVMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKLAPK 741
            +  E+N   +   +   T  ++ +AIE++GF   ++  T+ T    +   ++     CS+  V    + + ++KGV     +  +    VT+ P L+    + + +  +  D         KE +        + +++ I+GM C SC  TIE K+ +++G+  +KV+L +++    + P II+  +I+  IE  GF A +  K
Sbjct:   41 VSLEQNNATVTYDHTQHTPQSIADAIEDMGF---ESSLTNATSTPVQTETKVFSKAGCSADSVQQALSTLAQIKGVIETQESADNQGLAVTFVPSLVSEDQLGEVLKCLAPDTACRPPLSPKEGSTSRSFSGVEAVKMRIEGMVCLSCTTTIEGKIGKLKGVEKIKVSLESQEAAVVYLPYIITVDEIVKQIEVAGFKATVKSK 241

[Close]

BLAST of Copper-transporting ATPase 1 vs. Ensembl Zebrafish
Match: atp7b (ATPase copper transporting beta [Source:ZFIN;Acc:ZDB-GENE-061220-5])

HSP 1 Score: 817.379 bits (2110), Expect = 0.000e+0
Identity = 457/943 (48.46%), Postives = 626/943 (66.38%), Query Frame = 1

Query:  241 IENLGF-----------LINKNKETDNT--KELFKCHMRIQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMGFDAEIFQFKEHTKDIIEVMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKLAPKKT-NKYNDHVGESIKKWKHSFLISLIFGVPTMIVMMVFMYGFSHRMQVIHLKNGINVTVMVSNAPIXXXXXXXXXXXXXXXXXPVQFYGARYFYVQAYKSIKHGSANMDVLVVMATSVSYIYSFIVILVSMILRQDSSPQTFFETTPMLIVFLSLGRWLEHIAKGKTSEALSKLLSLQAFEATIIV--NDN---QERKISXXXXXXXXXXXXXPGEKIPIDGRVVSGKSRCDESLITGESMSVEKIPGSDVIGGTLNISGMLIIRATLVGEDSALNQIVKLVEEAQTSKAPIQELADKVAGLFVPGVIICSMFTLLIWIAIGYTNPNL----LPGHSSINTDNTELIWKYAFQLAITVLSVACPCSLGLATPTAVMVGTGVGAINGILIKGGVPLEKMHQLDVIVFDKTGTITTGKPSVTNFVMCVENVTSQIRNCILLMLGAAESSSEHPIGKAILQYVRETCDINEMPQVVHSKSVSGFGLECSLKLQSDMFVPDSEIDNVLVKINDFQENNLTENLKETSVKWRKINEPVEVVLYLGNRNMMKENHISIPDKLDELMSRDEDNGRTVVLMAIDKVLLAMISIADQVKKEAALVVYTLEKMGVEVFLLTGDNHKTATAIAKEIGIRNVFAEVLPSHKVAKIQQIQNMSKYKRSWLFSCCSKPSKLTNVAMVGDGINDSPALAQADVGIAIGTGTDVAVEAADVVLIRNSLLDVIAAMKLSKDTVRRIRQNFVAATMYNLIGIPIAAGALMPIGVVFMPWMA 3000
            IE++GF           + NK K  D T  +EL KC + + GMTC+SCV  IE  ++K +G+KS L+ L++   EV YDP L+  + I   I+ +GF A + +       ++++ + GMTC+SCV+ IESKL + +GI    VAL T K   KFD  ++  RDI+  IE +GF   L   +  N   DH  E I++WKHSFL SL+FG+P M +M+  M      M   H ++G ++    +  P    GLS+ NL  FL  +PVQF G RYFY+QAY+S++HG ANMDVL+V+AT+++Y+YSF V++V+MI     SP TFF+T PML VF++LGRWLEH+AK KTSEAL+KL+SLQA +ATI+    DN   +E ++SVDLV++GD+VKV PG K P+DG+V+ G S  DESLITGE M V K  GS VI G++N  G L++ AT VG ++ L+QIVKLVEEAQTSKAPIQ+LADK++G FVP +++ S+ T+  W+ IG+ + ++     PG++  N   TE+I ++AFQ +ITVLS+ACPCSLGLATPTAVMVGTGVGA NGILIKGG PLE  H++  ++FDKTGTIT G P VT  ++  +     +R  +L ++G AE+SSEHP+G A+ ++ +E      +      ++V G G+ C +          S ++++L       E++L  +    S      + P   VL +GNR  M  N + +   +D  MS  E  G+T +L+AID VL AMI++AD VK E+AL V+TL  MG+EV+++TGDN +TA AIA ++GIR VFAEVLPSHKVAK+Q++Q                  +   VAMVGDG+NDSPALA AD+GIAIGTGTDVA+EAAD+VLIRN LLDV+A+++LSK TV+RIR NFV A +YNL+GIP AAG  MP+G+V  PWM 
Sbjct:  236 IEDMGFEAWLNQGRYLLIHNKYKNADGTGERELRKCFVHVTGMTCASCVSNIERNLVKHEGIKSVLVALMAGKAEVKYDPGLLDPAQIVQLISHLGFGASVMEEHSVQDGVLDLSVTGMTCASCVHNIESKLLRTKGIQEASVALATNKAHVKFDSDLVGSRDIVRIIEGLGFGVSLIKNEGLNNTLDH-QEEIRQWKHSFLFSLVFGIPVMGLMIYMMV-----MDSQHKEHGGSMPADQNILP----GLSIINLAFFLLCTPVQFLGGRYFYIQAYRSLRHGVANMDVLIVLATTIAYVYSFTVLIVAMIEGAKQSPLTFFDTPPMLFVFIALGRWLEHVAKSKTSEALAKLMSLQATDATIVSLGPDNTIIREEQVSVDLVQRGDVVKVAPGGKFPVDGKVIEGTSMADESLITGEPMPVIKKAGSCVIAGSINAHGALLVEATHVGSETTLSQIVKLVEEAQTSKAPIQQLADKLSGYFVPFIVVISILTVTAWLIIGFLDFDVVSKNFPGYNQ-NISRTEVIVRFAFQASITVLSIACPCSLGLATPTAVMVGTGVGAQNGILIKGGEPLEMAHKVGAVMFDKTGTITNGVPQVTRVLVLWDRARLPLRT-VLAVVGTAEASSEHPLGMAVAKHCKEELGAETLGFCHDFQAVPGCGISCKV----------SSVEDLLQNRVTTDESSLVADTDSGS------DSPSYSVL-IGNRQWMLRNGLEVTADVDNAMSSHETKGQTAILVAIDGVLCAMIAVADTVKAESALAVHTLSSMGIEVYMITGDNRRTARAIATQVGIRKVFAEVLPSHKVAKVQELQE-----------------RGLKVAMVGDGVNDSPALAHADLGIAIGTGTDVAIEAADIVLIRNDLLDVVASIELSKKTVQRIRINFVFALIYNLLGIPFAAGVFMPLGLVLQPWMG 1132

HSP 2 Score: 84.3445 bits (207), Expect = 6.174e-16
Identity = 51/169 (30.18%), Postives = 83/169 (49.11%), Query Frame = 1

Query:  313 MRIQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMGFDAEI-FQFKEHTKDIIEVMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKLAPKKT----NKYNDHVGESIKKWKHSFL 804
            + ++GM C SCV  I   +  + GV S  ++L     ++ +DP L+    +       GF  EI           + + I+GMTC+SCV  IE  ++Q  G+ S+KV L  +KG   FD  +  P ++   IE+MGF+A L   +     NKY +  G   ++ +  F+
Sbjct:  111 LGVEGMHCGSCVKNITETLSGMLGVNSVFVSLEKGSVDLRFDPSLLTLETVK------GFLEEIPLNSASTPTQSVTIGIEGMTCNSCVQAIEGMMSQRAGVCSIKVYLQEKKGIVTFDSTVTCPEELRAEIEDMGFEAWLNQGRYLLIHNKYKNADGTGERELRKCFV 273

[Close]

BLAST of Copper-transporting ATPase 1 vs. Ensembl Zebrafish
Match: atp7a (ATPase copper transporting alpha [Source:ZFIN;Acc:ZDB-GENE-060825-45])

HSP 1 Score: 814.298 bits (2102), Expect = 0.000e+0
Identity = 455/950 (47.89%), Postives = 613/950 (64.53%), Query Frame = 1

Query:  286 NTKELFKCHMRIQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMGFDAEIFQFKEHTKDIIEVMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKLAPK-KTNKYNDHVGESIKKWKHSFLISLIFGVPTMIVMMVFMYGFSHRMQVIHLKNGINVTVMVSNAPIXXXXXXXXXXXXXXXX------XPVQFYGARYFYVQAYKSIKHGSANMDVLVVMATSVSYIYSFIVILVSMILRQDSSPQTFFETTPMLIVFLSLGRWLEHIAKGKTSEALSKLLSLQAFEATII-VNDN----QERKISXXXXXXXXXXXXXPGEKIPIDGRVVSGKSRCDESLITGESMSVEKIPGSDVIGGTLNISGMLIIRATLVGEDSALNQIVKLVEEAQTSKAPIQELADKVAGLFVPGVIICSMFTLLIWIAIGYTNPNLL----PGHSSINTDNTELIWKYAFQLAITVLSVACPCSLGLATPTAVMVGTGVGAINGILIKGGVPLEKMHQLDVIVFDKTGTITTGKPSVTNFVMCVENVTSQIRNCILLMLGAAESSSEHPIGKAILQYVRETCDINEMPQVVHSKSVSGFGLEC------SLKLQSDMFVPDSEIDNVLVKINDFQENNLTENLKETSVKWRKINEPVEVVLYLGNRNMMKENHISIPDKLDELMSRDEDNGRTVVLMAIDKVLLAMISIADQVKKEAALVVYTLEKMGVEVFLLTGDNHKTATAIAKEI------------------GIRNVFAEVLPSHKVAKIQQIQNMSKYKRSWLFSCCSKPSKLTNVAMVGDGINDSPALAQADVGIAIGTGTDVAVEAADVVLIRNSLLDVIAAMKLSKDTVRRIRQNFVAATMYNLIGIPIAAGALMPIGVVFMPWMASVAMA 3015
            +T  + KC ++I GMTC+SCV  IE  +    G+ S L+ L+++  EV Y P +I    IA+ I ++GF A +    + +   +E++++GMTC+SCV+ IES L + +GIL   VAL+T K   K+DP++  PRDI+  IE MGF A L  K +   + DH  E I++WK SF ISL F VP M  MM++M    H +   H  +             +F    L   L  +         PVQF G RYFY QAYK++KH +ANMDVL+V+AT++++ YS +V+LV+M+ R   +P TFF+T PML VF+SLGRWLE IAK KTSEALSKL+SLQA EAT++ +N++     E ++ V+LV++GD+VKV+PG K P+DGRV+ G S  DESLITGE+M V K PGS VI G++N +G L+I+AT VG D+ L+QIVKLVEEAQTSKAPIQ+ ADK++  FVP +++ S+ TLL WI IG+ N +L+    PG+   +    E + ++AFQ +ITVL +ACPCSLGLATPTAVMVGTGVGA NGILIKGG PLE  H++  +VFDKTGTIT G P V    M  E      R+ +L ++G AE+SSEHP+G AI +Y ++      +      ++V G G+ C      +L  + D    +++ + VL++I+D + ++ TE+      +   + +     + +GNR  M+ N + +   +DE M+  E  G T VL+A+D  L AM++IAD VK EA L V+ L  MG+EV L+TGDN KTA AIA ++                  GIR VFAEVLPSHKVAK++Q+Q   K                  VAMVGDG+NDSPALA ADVGIAIGTGTDVA+EAADVVLIRN LLDV+ ++ LSK TV+RIR NFV A MYNL+GIPIAAG  MP+G+V  PWM S AMA
Sbjct:  468 STNTISKCFIQIGGMTCASCVANIERNLKNEYGIHSVLVALMASKAEVRYSPSVIDPLRIAELIRELGFTATVMDNYDGSDGSLELVVRGMTCASCVHKIESNLMKQKGILYASVALSTNKAHIKYDPEVTGPRDIIRLIENMGFTASLVKKDRPGSHLDHSRE-IRQWKRSFQISLFFCVPVM-GMMIYMIVVDHMIDKYHQHHNATAEDRAKYHSTMFLEKQLLPGLSIMNLISFLFCVPVQFIGGRYFYCQAYKAVKHRTANMDVLIVLATTIAFTYSVVVLLVAMVERAKVNPITFFDTPPMLFVFISLGRWLEQIAKSKTSEALSKLMSLQATEATVVTLNEDMSVLSEEQVDVELVQRGDVVKVVPGGKFPVDGRVIEGHSMADESLITGEAMPVTKKPGSTVIAGSINQNGSLLIKATHVGTDTTLSQIVKLVEEAQTSKAPIQQFADKISSYFVPFIVVISVLTLLAWIIIGFVNFSLVQTYFPGYDK-SISEAEAVIRFAFQASITVLCIACPCSLGLATPTAVMVGTGVGAQNGILIKGGEPLEMAHKIQSVVFDKTGTITYGAPKVVQVKMLAEG-NRLPRSKLLAIVGTAENSSEHPLGAAITKYCKQELGTESLGTCTDFQAVPGCGIRCLVSNTENLLKREDSDSEENQHNAVLIQISDARAHS-TEHPLIMDPQPLTVVQTASYTVLIGNREWMRRNALQVRADVDEAMTEHERRGCTAVLVAVDNELCAMVAIADTVKPEAELAVHVLSAMGLEVVLMTGDNSKTARAIAAQVKNHLILPQNAPILLFRMVGIRKVFAEVLPSHKVAKVEQLQQEGK-----------------RVAMVGDGVNDSPALAMADVGIAIGTGTDVAIEAADVVLIRNDLLDVVGSIDLSKKTVKRIRINFVFALMYNLVGIPIAAGVFMPVGLVLQPWMGSAAMA 1395

HSP 2 Score: 98.2117 bits (243), Expect = 4.769e-20
Identity = 52/148 (35.14%), Postives = 85/148 (57.43%), Query Frame = 1

Query:  313 MRIQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDM---GFDAEIFQ-----FKEHTKDIIEVMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKL 732
             ++ GM C+SCV  I++ + KL  V S +++L +    + ++P  + A ++   I  +    F A I       F +    + E+ I+GMTC SCV +IE  L+Q +G+ S +V+L   KG F++DP + SP ++  AIE+MGFDA L
Sbjct:  279 FQVTGMHCNSCVVNIQDNISKLPAVTSVVVSLENRQASIQHNPKQVSAVELQKAIEALPPGNFKAIIPASPEPGFLQPLVSVAEIHIEGMTCGSCVQSIEGTLSQKKGVRSAQVSLANHKGTFEYDPLLTSPEELRAAIEDMGFDAFL 426

HSP 3 Score: 94.7449 bits (234), Expect = 4.825e-19
Identity = 70/246 (28.46%), Postives = 105/246 (42.68%), Query Frame = 1

Query:  121 IEDFFQFNDNIKTVVIDYEKNLVRICCHNDNCTYLTLCEAIE-----NLGFLINKNKETDNTKELFK-CHMRIQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMGFDAEIFQFKEHTKDIIE--------------------------------------VMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDA 726
            I+D       + +VV+  E     I  +    + + L +AIE     N   +I  + E    + L     + I+GMTC SCV +IE  + + KGV+SA ++L +  G   YDP L    ++   I DMGFDA + +       +++                                      + I GMTC+SCV  IE  L    GI SV VAL   K + ++ P +I P  I + I E+GF A
Sbjct:  293 IQDNISKLPAVTSVVVSLENRQASIQHNPKQVSAVELQKAIEALPPGNFKAIIPASPEPGFLQPLVSVAEIHIEGMTCGSCVQSIEGTLSQKKGVRSAQVSLANHKGTFEYDPLLTSPEELRAAIEDMGFDAFLPETNSLVPSVVKSPSLSVRSSSLSPVRSAVKENEAESDAEPSTNTISKCFIQIGGMTCASCVANIERNLKNEYGIHSVLVALMASKAEVRYSPSVIDPLRIAELIRELGFTA 538

HSP 4 Score: 59.3066 bits (142), Expect = 3.460e-8
Identity = 40/153 (26.14%), Postives = 69/153 (45.10%), Query Frame = 1

Query:  298 LFKCHMRIQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMGFDAEIFQFKEHTKDIIEVMIQGMTCSS-CVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKLAPKKTNK 753
            L +  + ++GMTC SCV +IE ++  L GV    ++L      VTYD        IAD I DMGF++ +             +     CS+  V    S LAQ++G++  + +   +     F P ++S   + + ++ +  D    P  + K
Sbjct:    7 LCRVTLGVEGMTCGSCVQSIEGRIGGLPGVIHIQVSLEQNNATVTYDHTQHTPQSIADAIEDMGFESSLTNATSTPVQTETKVFSKAGCSADSVQQALSTLAQIKGVIETQESADNQGLAVTFVPSLVSEDQLGEVLKCLAPDTACRPPLSPK 159

HSP 5 Score: 55.0694 bits (131), Expect = 6.446e-7
Identity = 47/204 (23.04%), Postives = 96/204 (47.06%), Query Frame = 1

Query:  166 IDYEKNLVRICCHNDNCTYLTLCEAIENLGFLINKNKETDNTKELFKCHMRI-QGMTCSS-CVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMGFDAEI---FQFKEHTK-------DIIEVMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKLAPK 741
            +  E+N   +   +   T  ++ +AIE++GF   ++  T+ T    +   ++     CS+  V    + + ++KGV     +  +    VT+ P L+    + + +  +  D         KE +        + +++ I+GM C SC  TIE K+ +++G+  +KV+L +++    + P II+  +I+  IE  GF A +  K
Sbjct:   41 VSLEQNNATVTYDHTQHTPQSIADAIEDMGF---ESSLTNATSTPVQTETKVFSKAGCSADSVQQALSTLAQIKGVIETQESADNQGLAVTFVPSLVSEDQLGEVLKCLAPDTACRPPLSPKEGSTSRSFSGVEAVKMRIEGMVCLSCTTTIEGKIGKLKGVEKIKVSLESQEAAVVYLPYIITVDEIVKQIEVAGFKATVKSK 241

[Close]

BLAST of Copper-transporting ATPase 1 vs. Ensembl Zebrafish
Match: atp7b (ATPase copper transporting beta [Source:ZFIN;Acc:ZDB-GENE-061220-5])

HSP 1 Score: 805.438 bits (2079), Expect = 0.000e+0
Identity = 447/932 (47.96%), Postives = 616/932 (66.09%), Query Frame = 1

Query:  259 LINKNKETDNTKELFKCHMRIQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMGFDAEIFQFKEHTKDIIEVMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKLAPKKT-NKYNDHVGESIKKWKHSFLISLIFGVPTMIVMMVFMYGFSHRMQVIHLKNGINVTVMVSNAPIXXXXXXXXXXXXXXXXXPVQFYGARYFYVQAYKSIKHGSANMDVLVVMATSVSYIYSFIVILVSMILRQDSSPQTFFETTPMLIVFLSLGRWLEHIAKGKTSEALSKLLSLQAFEATIIV--NDN---QERKISXXXXXXXXXXXXXPGEKIPIDGRVVSGKSRCDESLITGESMSVEKIPGSDVIGGTLNISGMLIIRATLVGEDSALNQIVKLVEEAQTSKAPIQELADKVAGLFVPGVIICSMFTLLIWIAIGYTNPNL----LPGHSSINTDNTELIWKYAFQLAITVLSVACPCSLGLATPTAVMVGTGVGAINGILIKGGVPLEKMHQLDVIVFDKTGTITTGKPSVTNFVMCVENVTSQIRNCILLMLGAAESSSEHPIGKAILQYVRETCDINEMPQVVHSKSVSGFGLECSLKLQSDMFVPDSEIDNVLVKINDFQENNLTENLKETSVKWRKI--------NEPVEVVLYLGNRNMMKENHISIPDKLDELMSRDEDNGRTVVLMAIDKVLLAMISIADQVKKEAALVVYTLEKMGVEVFLLTGDNHKTATAIAKEIGIRNVFAEVLPSHKVAKIQQIQNMSKYKRSWLFSCCSKPSKLTNVAMVGDGINDSPALAQADVGIAIGTGTDVAVEAADVVLIRNSLLDVIAAMKLSKDTVRRIRQNFVAATMYNLIGIPIAAGALMPIGVVFMPWMA 3000
            +  +N +    +EL KC + + GMTC+SCV  IE  ++K +G+KS L+ L++   EV YDP L+  + I   I+ +GF A + +       ++++ + GMTC+SCV+ IESKL + +GI    VAL T K   KFD  ++  RDI+  IE +GF   L   +  N   DH  E   +WKHSFL SL+FG+P M +M+  M      M   H ++G ++    +  P    GLS+ NL  FL  +PVQF G RYFY+QAY+S++HG ANMDVL+V+AT+++Y+YSF V++V+MI     SP TFF+T PML VF++LGRWLEH+AK KTSEAL+KL+SLQA +ATI+    DN   +E ++SVDLV++GD+VKV PG K P+DG+V+ G S  DESLITGE M V K  GS VI G++N  G L++ AT VG ++ L+QIVKLVEEAQTSKAPIQ+LADK++G FVP +++ S+ T+  W+ IG+ + ++     PG++  N   TE+I ++AFQ +ITVLS+ACPCSLGLATPTAVMVGTGVGA NGILIKGG PLE  H++  ++FDKTGTIT G P VT  ++  +     +R  +L ++G AE+SSEHP+G A+ ++ +E      +      ++V G G+ C +    D+     +      K +  ++  L   L+  +     +        + P   VL +GNR  M  N + +   +D  MS  E  G+T +L+AID VL AMI++AD VK E+AL V+TL  MG+EV+++TGDN +TA AIA ++GIR VFAEVLPSHKVAK+Q++Q                  +   VAMVGDG+NDSPALA AD+GIAIGTGTDVA+EAAD+VLIRN LLDV+A+++LSK TV+RIR NFV A +YNL+GIP AAG  MP+G+V  PWM 
Sbjct:  369 ITKENADGTGERELRKCFVHVTGMTCASCVSNIERNLVKHEGIKSVLVALMAGKAEVKYDPGLLDPAQIVQLISHLGFGASVMEEHSVQDGVLDLSVTGMTCASCVHNIESKLLRTKGIQEASVALATNKAHVKFDSDLVGSRDIVRIIEGLGFGVSLIKNEGLNNTLDHQEE--IRWKHSFLFSLVFGIPVMGLMIYMMV-----MDSQHKEHGGSMPADQNILP----GLSIINLAFFLLCTPVQFLGGRYFYIQAYRSLRHGVANMDVLIVLATTIAYVYSFTVLIVAMIEGAKQSPLTFFDTPPMLFVFIALGRWLEHVAKSKTSEALAKLMSLQATDATIVSLGPDNTIIREEQVSVDLVQRGDVVKVAPGGKFPVDGKVIEGTSMADESLITGEPMPVIKKAGSCVIAGSINAHGALLVEATHVGSETTLSQIVKLVEEAQTSKAPIQQLADKLSGYFVPFIVVISILTVTAWLIIGFLDFDVVSKNFPGYNQ-NISRTEVIVRFAFQASITVLSIACPCSLGLATPTAVMVGTGVGAQNGILIKGGEPLEMAHKVGAVMFDKTGTITNGVPQVTRVLVLWDRARLPLRT-VLAVVGTAEASSEHPLGMAVAKHCKEELGAETLGFCHDFQAVPGCGISCKVSSVEDLLQNSPKTQET--KASAVKQTPLLVTLQGVTTDESSLVADTDSGSDSPSYSVL-IGNRQWMLRNGLEVTADVDNAMSSHETKGQTAILVAIDGVLCAMIAVADTVKAESALAVHTLSSMGIEVYMITGDNRRTARAIATQVGIRKVFAEVLPSHKVAKVQELQE-----------------RGLKVAMVGDGVNDSPALAHADLGIAIGTGTDVAIEAADIVLIRNDLLDVVASIELSKKTVQRIRINFVFALIYNLLGIPFAAGVFMPLGLVLQPWMG 1267

HSP 2 Score: 82.4185 bits (202), Expect = 2.475e-15
Identity = 47/140 (33.57%), Postives = 76/140 (54.29%), Query Frame = 1

Query:  313 MRIQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMGFDAEIF----QFKEHTKDIIEVM--IQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEM 714
            ++++GMTC SCV +IE Q+ +L+GV    ++L      + ++P  +   D+   I DMGFDA I     Q +  + D  EV   ++GM C SCV  I   L+ M G+ SV V+L       +FDP +++   +   +EE+
Sbjct:  103 IQVEGMTCQSCVRSIEEQIGRLEGVIGVQVSLSDKEAILRFNPAKVTPEDMRKRIEDMGFDALILALQGQIQPLSTDWSEVTLGVEGMHCGSCVKNITETLSGMLGVNSVFVSLEKGSVDLRFDPSLLTLETVKGFLEEI 242

HSP 3 Score: 80.8777 bits (198), Expect = 7.321e-15
Identity = 56/179 (31.28%), Postives = 79/179 (44.13%), Query Frame = 1

Query:  319 IQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMGFDAEIFQ----------------------------------FKEHTKDIIE-------VMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKL 732
            I+GMTC+SCV  IE  + +  GV S  + L    G VT+D  +    ++   I DMGF+A + Q                                   KE+     E       V + GMTC+SCV  IE  L + +GI SV VAL   K + K+DP ++ P  I+  I  +GF A +
Sbjct:  272 IEGMTCNSCVQAIEGMMSQRAGVCSIKVYLQEKKGIVTFDSTVTCPEELRAEIEDMGFEAWLNQDSEICEVSSVSQMPSGLKHLPSQRHPSKPSPSPITKENADGTGERELRKCFVHVTGMTCASCVSNIERNLVKHEGIKSVLVALMAGKAEVKYDPGLLDPAQIVQLISHLGFGASV 450

HSP 4 Score: 80.1073 bits (196), Expect = 1.543e-14
Identity = 49/178 (27.53%), Postives = 89/178 (50.00%), Query Frame = 1

Query:  241 IENLGF----LINKNKETDNTKELFKCHMRIQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDM----------GFDAEIFQFKEHTKDIIEVMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKL 732
            IE++GF    L  + +    + +  +  + ++GM C SCV  I   +  + GV S  ++L     ++ +DP L+    +   + ++          G+ + +      T+ +  + I+GMTC+SCV  IE  ++Q  G+ S+KV L  +KG   FD  +  P ++   IE+MGF+A L
Sbjct:  157 IEDMGFDALILALQGQIQPLSTDWSEVTLGVEGMHCGSCVKNITETLSGMLGVNSVFVSLEKGSVDLRFDPSLLTLETVKGFLEEIPPGNFRVSIPGWSSRLNSASTPTQSVT-IGIEGMTCNSCVQAIEGMMSQRAGVCSIKVYLQEKKGIVTFDSTVTCPEELRAEIEDMGFEAWL 333

HSP 5 Score: 68.1662 bits (165), Expect = 5.799e-11
Identity = 24/67 (35.82%), Postives = 50/67 (74.63%), Query Frame = 1

Query:  526 KDIIEVMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDA 726
            + ++++ ++GMTC SCV +IE ++ +++G++ V+V+L+ ++   +F+P  ++P D+   IE+MGFDA
Sbjct:   98 EGMVKIQVEGMTCQSCVRSIEEQIGRLEGVIGVQVSLSDKEAILRFNPAKVTPEDMRKRIEDMGFDA 164

[Close]

BLAST of Copper-transporting ATPase 1 vs. Ensembl Zebrafish
Match: atp7a (ATPase copper transporting alpha [Source:ZFIN;Acc:ZDB-GENE-060825-45])

HSP 1 Score: 765.763 bits (1976), Expect = 0.000e+0
Identity = 435/928 (46.88%), Postives = 582/928 (62.72%), Query Frame = 1

Query:  286 NTKELFKCHMRIQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMGFDAEIFQFKEHTKDIIEVMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKLAPK-KTNKYNDHVGESIKKWKHSFLISLIFGVPTMIVMMVFMYGFSHRMQVIHLKNGINVTVMVSNAPIXXXXXXXXXXXXXXXX------XPVQFYGARYFYVQAYKSIKHGSANMDVLVVMATSVSYIYSFIVILVSMILRQDSSPQTFFETTPMLIVFLSLGRWLEHIAKGKTSEALSKLLSLQAFEATII-VNDN----QERKISXXXXXXXXXXXXXPGEKIPIDGRVVSGKSRCDESLITGESMSVEKIPGSDVIGGTLNISGMLIIRATLVGEDSALNQIVKLVEEAQTSKAPIQELADKVAGLFVPGVIICSMFTLLIWIAIGYTNPNLLPGHSSINTDNTELIWKYAFQLAITVLSVACPCSLGLATPTAVMVGTGVGAINGILIKGGVPLEKMHQLDVIVFDKTGTITTGKPSVTNFVMCVENVTSQIRNCILLMLGAAESSSEHPIGKAILQYVRETCDINEMPQVVHSKSVSGFGLEC------SLKLQSDMFVPDSEIDNVLVKINDFQENNLTENLKETSVKWRKINEPVEVVLYLGNRNMMKENHISIPDKLDELMSRDEDNGRTVVLMAIDKVLLAMISIADQVKKEAALVVYTLEKMGVEVFLLTGDNHKTATAIAKEIGIRNVFAEVLPSHKVAKIQQIQNMSKYKRSWLFSCCSKPSKLTNVAMVGDGINDSPALAQADVGIAIGTGTDVAVEAADVVLIRNSLLDVIAAMKLSKDTVRRIRQNFVAATMYNLIGIPIAAGALMPIGVVFMPWMASVAMA 3015
            +T  + KC ++I GMTC+SCV  IE  +    G+ S L+ L+++  EV Y P +I    IA+ I ++GF A +    + +   +E++++GMTC+SCV+ IES L + +GIL   VAL+T K   K+DP++  PRDI+  IE MGF A L  K +   + DH  E I++WK SF ISL F VP M  MM++M    H +   H  +             +F    L   L  +         PVQF G RYFY QAYK++KH +ANMDVL+V+AT++++ YS +V+LV+M+ R   +P TFF+T PML VF+SLGRWLE IAK KTSEALSKL+SLQA EAT++ +N++     E ++ V+LV++GD+VKV+PG K P+DGRV+ G S  DESLITGE+M V K PGS VI G++N +G L+I+AT VG D+ L+QIVKLVEEAQTSK                                GY            +    E + ++AFQ +ITVL +ACPCSLGLATPTAVMVGTGVGA NGILIKGG PLE  H++  +VFDKTGTIT G P V    M  E      R+ +L ++G AE+SSEHP+G AI +Y ++      +      ++V G G+ C      +L  + D    +++ + VL++I+D + ++ TE+      +   + +     + +GNR  M+ N + +   +DE M+  E  G T VL+A+D  L AM++IAD VK EA L V+ L  MG+EV L+TGDN KTA AIA ++GIR VFAEVLPSHKVAK++Q+Q   K                  VAMVGDG+NDSPALA ADVGIAIGTGTDVA+EAADVVLIRN LLDV+ ++ LSK TV+RIR NFV A MYNL+GIPIAAG  MP+G+V  PWM S AMA
Sbjct:  468 STNTISKCFIQIGGMTCASCVANIERNLKNEYGIHSVLVALMASKAEVRYSPSVIDPLRIAELIRELGFTATVMDNYDGSDGSLELVVRGMTCASCVHKIESNLMKQKGILYASVALSTNKAHIKYDPEVTGPRDIIRLIENMGFTASLVKKDRPGSHLDHSRE-IRQWKRSFQISLFFCVPVM-GMMIYMIVVDHMIDKYHQHHNATAEDRAKYHSTMFLEKQLLPGLSIMNLISFLFCVPVQFIGGRYFYCQAYKAVKHRTANMDVLIVLATTIAFTYSVVVLLVAMVERAKVNPITFFDTPPMLFVFISLGRWLEQIAKSKTSEALSKLMSLQATEATVVTLNEDMSVLSEEQVDVELVQRGDVVKVVPGGKFPVDGRVIEGHSMADESLITGEAMPVTKKPGSTVIAGSINQNGSLLIKATHVGTDTTLSQIVKLVEEAQTSK--------------------------------GYDK----------SISEAEAVIRFAFQASITVLCIACPCSLGLATPTAVMVGTGVGAQNGILIKGGEPLEMAHKIQSVVFDKTGTITYGAPKVVQVKMLAEG-NRLPRSKLLAIVGTAENSSEHPLGAAITKYCKQELGTESLGTCTDFQAVPGCGIRCLVSNTENLLKREDSDSEENQHNAVLIQISDARAHS-TEHPLIMDPQPLTVVQTASYTVLIGNREWMRRNALQVRADVDEAMTEHERRGCTAVLVAVDNELCAMVAIADTVKPEAELAVHVLSAMGLEVVLMTGDNSKTARAIAAQVGIRKVFAEVLPSHKVAKVEQLQQEGK-----------------RVAMVGDGVNDSPALAMADVGIAIGTGTDVAIEAADVVLIRNDLLDVVGSIDLSKKTVKRIRINFVFALMYNLVGIPIAAGVFMPVGLVLQPWMGSAAMA 1332

HSP 2 Score: 97.8265 bits (242), Expect = 5.324e-20
Identity = 52/147 (35.37%), Postives = 85/147 (57.82%), Query Frame = 1

Query:  316 RIQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDM---GFDAEIFQ-----FKEHTKDIIEVMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKL 732
            ++ GM C+SCV  I++ + KL  V S +++L +    + ++P  + A ++   I  +    F A I       F +    + E+ I+GMTC SCV +IE  L+Q +G+ S +V+L   KG F++DP + SP ++  AIE+MGFDA L
Sbjct:  280 QVTGMHCNSCVVNIQDNISKLPAVTSVVVSLENRQASIQHNPKQVSAVELQKAIEALPPGNFKAIIPASPEPGFLQPLVSVAEIHIEGMTCGSCVQSIEGTLSQKKGVRSAQVSLANHKGTFEYDPLLTSPEELRAAIEDMGFDAFL 426

HSP 3 Score: 94.7449 bits (234), Expect = 5.300e-19
Identity = 70/246 (28.46%), Postives = 105/246 (42.68%), Query Frame = 1

Query:  121 IEDFFQFNDNIKTVVIDYEKNLVRICCHNDNCTYLTLCEAIE-----NLGFLINKNKETDNTKELFK-CHMRIQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMGFDAEIFQFKEHTKDIIE--------------------------------------VMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDA 726
            I+D       + +VV+  E     I  +    + + L +AIE     N   +I  + E    + L     + I+GMTC SCV +IE  + + KGV+SA ++L +  G   YDP L    ++   I DMGFDA + +       +++                                      + I GMTC+SCV  IE  L    GI SV VAL   K + ++ P +I P  I + I E+GF A
Sbjct:  293 IQDNISKLPAVTSVVVSLENRQASIQHNPKQVSAVELQKAIEALPPGNFKAIIPASPEPGFLQPLVSVAEIHIEGMTCGSCVQSIEGTLSQKKGVRSAQVSLANHKGTFEYDPLLTSPEELRAAIEDMGFDAFLPETNSLVPSVVKSPSLSVRSSSLSPVRSAVKENEAESDAEPSTNTISKCFIQIGGMTCASCVANIERNLKNEYGIHSVLVALMASKAEVRYSPSVIDPLRIAELIRELGFTA 538

HSP 4 Score: 58.9214 bits (141), Expect = 3.734e-8
Identity = 40/153 (26.14%), Postives = 69/153 (45.10%), Query Frame = 1

Query:  298 LFKCHMRIQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMGFDAEIFQFKEHTKDIIEVMIQGMTCSS-CVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKLAPKKTNK 753
            L +  + ++GMTC SCV +IE ++  L GV    ++L      VTYD        IAD I DMGF++ +             +     CS+  V    S LAQ++G++  + +   +     F P ++S   + + ++ +  D    P  + K
Sbjct:    7 LCRVTLGVEGMTCGSCVQSIEGRIGGLPGVIHIQVSLEQNNATVTYDHTQHTPQSIADAIEDMGFESSLTNATSTPVQTETKVFSKAGCSADSVQQALSTLAQIKGVIETQESADNQGLAVTFVPSLVSEDQLGEVLKCLAPDTACRPPLSPK 159

HSP 5 Score: 54.6842 bits (130), Expect = 8.039e-7
Identity = 47/204 (23.04%), Postives = 96/204 (47.06%), Query Frame = 1

Query:  166 IDYEKNLVRICCHNDNCTYLTLCEAIENLGFLINKNKETDNTKELFKCHMRI-QGMTCSS-CVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMGFDAEI---FQFKEHTK-------DIIEVMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKLAPK 741
            +  E+N   +   +   T  ++ +AIE++GF   ++  T+ T    +   ++     CS+  V    + + ++KGV     +  +    VT+ P L+    + + +  +  D         KE +        + +++ I+GM C SC  TIE K+ +++G+  +KV+L +++    + P II+  +I+  IE  GF A +  K
Sbjct:   41 VSLEQNNATVTYDHTQHTPQSIADAIEDMGF---ESSLTNATSTPVQTETKVFSKAGCSADSVQQALSTLAQIKGVIETQESADNQGLAVTFVPSLVSEDQLGEVLKCLAPDTACRPPLSPKEGSTSRSFSGVEAVKMRIEGMVCLSCTTTIEGKIGKLKGVEKIKVSLESQEAAVVYLPYIITVDEIVKQIEVAGFKATVKSK 241

[Close]

BLAST of Copper-transporting ATPase 1 vs. Ensembl Xenopus
Match: dhx34 (DEAH-box helicase 34 [Source:Xenbase;Acc:XB-GENE-1009178])

HSP 1 Score: 841.647 bits (2173), Expect = 0.000e+0
Identity = 481/1006 (47.81%), Postives = 672/1006 (66.80%), Query Frame = 1

Query:  238 AIENLGF----LINKNKETD-----NTKELFKCHMRIQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMGFDAEIFQFKEHTKDIIEVMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKLAPK-KTNKYNDHVGESIKKWKHSFLISLIFGVPTMIVMMVFMYGFSHRMQVIHLKNGINVTVMVSNAPIXXXX------XXXXXXXXXXXXXPVQFYGARYFYVQAYKSIKHGSANMDVLVVMATSVSYIYSFIVILVSMILRQDSSPQTFFETTPMLIVFLSLGRWLEHIAKGKTSEALSKLLSLQAFEATIIVND-----NQERKISXXXXXXXXXXXXXPGEKIPIDGRVVSGKSRCDESLITGESMSVEKIPGSDVIGGTLNISGMLIIRATLVGEDSALNQIVKLVEEAQTSKAPIQELADKVAGLFVPGVIICSMFTLLIWIAIGYTN----PNLLPGHSSINTDNTELIWKYAFQLAITVLSVACPCSLGLATPTAVMVGTGVGAINGILIKGGVPLEKMHQLDVIVFDKTGTITTGKPSVTNFVMCVENVTSQIRNCILLMLGAAESSSEHPIGKAILQYVRETCDINEMPQVVHSKSVSGFGLECSLK----LQSDMFVPDSEIDNVLVKINDFQENNLTENLKETSVKWRKINEPVEVV-LYLGNRNMMKENHISIPDKLDELMSRDEDNGRTVVLMAIDKVLLAMISIADQVKKEAALVVYTLEKMGVEVFLLTGDNHKTATAIAKEIGIRNVFAEVLPSHKVAKIQQIQNMSKYKRSWLFSCCSKPSKLTNVAMVGDGINDSPALAQADVGIAIGTGTDVAVEAADVVLIRNSLLDVIAAMKLSKDTVRRIRQNFVAATMYNLIGIPIAAGALMPIGVVFMPWMASVAMAASSICVVCXXXXXXXXXXPNEDQLANQEFKNHLECLKYGDMEVGVNLGKD 3165
            AIE++GF    L   NKET        + + KC ++I GMTC+SCV  IE  + + +G+ S L+ L++   EV Y+P+++  S IA+ I ++GF+A + +  +    I+E++++GMTC+SCV+ IES+L + +G+L   VAL T K   KFDP++I PRDI+  I ++GF   L  K ++  + DH  E I++WK SFLISLIF +P M +M+  M+  +H +   H  + + +  + S  P +         LS+ NL+  L   PVQF G  YFY+QAYK++KH +ANMDVL+V+ATSV++IYS IV++V++  +   +P TFF+T PML VF++LGRWLEHIAK KTSEALS+L+SLQA EAT+++ D       E ++ V+LV++GD+V+V PG K P+DGRV+ G+S  DESLITGE+M V K PGS VI G++N +G L+I AT VG D+ L+QIVKLVE+AQTSKAPIQ+ ADK++G FVP ++  S+ TL +WI IGY N        PG++  +    E+I ++AFQ AITVL +ACPCSLGLATPTAVMVGTGVGA NGILIKGG PLE  H++  +VFDKTGTIT G P V    + VE+      N +L ++G AES+SEHP+G A+++Y +E  +   +      ++V G G+ C +     L      PD++ + VLV+I+   E+++   L   +V     + P +   + +GNR  M  N +++  + D LM+  E  GRT VL+A+D VL  +I+IAD VK EAAL +++L  MG+++ L+TGDN KTA  IA ++GI  VFAEVLPSHKVAK++Q+Q                    T VAMVGDGINDSPALA ADVGI IG+GTDVA+EAADVVLIRN LLDV+A++ LS+ TV+RIR NFV A +YNL+GIPIAAG  MP+G++  PWM S AMAASS+ VV  SLLLKL++KP+ ++L  Q  +  +      D+ V + L ++
Sbjct:  434 AIEDMGFDASLLERTNKETPVHSKPEKRTVNKCFIQITGMTCASCVANIERNLRREEGIYSVLVALMAGKAEVRYNPEVLQPSGIAELIQELGFEASVLENYDDGTGILELLVRGMTCASCVHKIESRLMKTKGVLYSSVALATNKAHIKFDPEVIGPRDIMKIINDLGFSTSLVKKDRSASHLDHRVE-IQRWKRSFLISLIFCIPVMGLMVHMMFMENHYLMPHH--HNMTMEDIASYHPTMVLEYQIIPGLSIMNLVSLLLCIPVQFLGGWYFYIQAYKALKHRTANMDVLIVLATSVAFIYSLIVLIVAIFEKSKVNPITFFDTPPMLFVFIALGRWLEHIAKSKTSEALSRLISLQATEATVVILDPDNTVKSEEQVDVELVQRGDIVRVTPGGKFPVDGRVIEGQSMVDESLITGEAMPVSKKPGSSVIAGSINQNGSLLIAATHVGSDTTLSQIVKLVEDAQTSKAPIQQFADKLSGYFVPFIVAVSVLTLFVWIIIGYHNFEIVEKYFPGYNK-SISKGEVIVRFAFQAAITVLCIACPCSLGLATPTAVMVGTGVGAQNGILIKGGEPLEMAHKVKTVVFDKTGTITKGTPVVMQVKVLVES-NRMPSNKLLAIVGTAESNSEHPLGSAVIKYCKEVLNAETLGTCYDFQAVPGCGISCKVNNIEPLLHAANGPDNKRNAVLVQIDGQHEDSI---LPSITVSQNPSSSPPQTYSVLIGNREWMNRNFLTLTAETDSLMTEHEKKGRTAVLVAVDGVLCGLIAIADTVKPEAALAIHSLRSMGLDIVLMTGDNSKTAKTIAAQVGITKVFAEVLPSHKVAKVKQLQEQG-----------------TRVAMVGDGINDSPALAMADVGITIGSGTDVAIEAADVVLIRNDLLDVVASIDLSRKTVKRIRINFVFALIYNLVGIPIAAGVFMPVGLILQPWMGSAAMAASSVSVVFSSLLLKLYRKPSREKL-EQRVQGQMRQKSLSDISVHIGLTEN 1413

HSP 2 Score: 84.3445 bits (207), Expect = 9.808e-16
Identity = 56/183 (30.60%), Postives = 89/183 (48.63%), Query Frame = 1

Query:  295 ELFKCHMRIQGMTCSSCVHTIENQVLKLKGVKS----------------------ALINLLSTIGEVTYDPDLIMASDIADTIN-----DMGFDAEIFQF---KEHTKDIIEVMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKLAPKKTNK 753
            +L +   +I+GM C SCV  IE+ +    GV S                      ALI  +  +   T+   L    ++A+T +     +     EIF     ++    +  + I+GMTC SCV +IE  +++  G+ S++V+L    G  ++DP + SP DI  AIE+MGFDA L  ++TNK
Sbjct:  269 DLIRAIFQIEGMHCKSCVVNIESNIGSQHGVSSIEVSLENKLAVIHFYSNITTSDALIQAIEALSPGTFKVSLCNHPELAETFSMQKNSEASCAKEIFSSPSNQDFCSKVTVINIEGMTCMSCVQSIEGLISKKPGVKSIQVSLVNNNGTVQYDPAVTSPEDIRAAIEDMGFDASLL-ERTNK 450

HSP 3 Score: 71.633 bits (174), Expect = 9.018e-12
Identity = 48/187 (25.67%), Postives = 86/187 (45.99%), Query Frame = 1

Query:  229 LCEAIENLGFLINKNKETDNTKELFKCHMRIQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMGFDAEIFQFKEHTKDIIE------------VMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKLAPKKTNK 753
            L EA+E++GF    +        +    +R   ++       I + + + KGV     +L   +  VT+ P ++    +   I  +  D+     K+ T   +E            + I+GMTC SC  TIE K+ +++G+  +KV+L +++ +  + P +I P DI   IEE GF A++  K   K
Sbjct:   58 LQEAVEDMGFESTLSYANPQPVPMDSTFLR---LSAEQSAEQIRSGLSQFKGVLDVKTSLEGKVACVTFIPSVVNPGLLIQKIPGLSLDS--MASKKTTSGSVESRSSVASDVLVKMKIEGMTCHSCTSTIEGKVGKLKGVQRIKVSLDSQEAQILYQPHLIKPEDIRTQIEEAGFIAQIKSKPPQK 239

HSP 4 Score: 68.9366 bits (167), Expect = 5.515e-11
Identity = 40/149 (26.85%), Postives = 74/149 (49.66%), Query Frame = 1

Query:  301 FKCHMRIQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMGFDAEIFQFKEHTKDIIEVMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKLAPKKT 747
            F   + ++GMTC+SCV TIE ++  + GV S  ++L      + YD  L     + + + DMGF++ +         +    ++ ++       I S L+Q +G+L VK +L  +     F P +++P  ++  I  +  D+ +A KKT
Sbjct:    4 FLAFIPVEGMTCNSCVQTIEQKIGSINGVHSIKVSLEGKNAAIIYDAKLQTPKALQEAVEDMGFESTLSYANPQPVPMDSTFLR-LSAEQSAEQIRSGLSQFKGVLDVKTSLEGKVACVTFIPSVVNPGLLIQKIPGLSLDS-MASKKT 150

[Close]

BLAST of Copper-transporting ATPase 1 vs. Ensembl Xenopus
Match: dhx34 (DEAH-box helicase 34 [Source:Xenbase;Acc:XB-GENE-1009178])

HSP 1 Score: 837.025 bits (2161), Expect = 0.000e+0
Identity = 451/935 (48.24%), Postives = 629/935 (67.27%), Query Frame = 1

Query:  271 NKETD-----NTKELFKCHMRIQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMGFDAEIFQFKEHTKDIIEVMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKLAPK-KTNKYNDHVGESIKKWKHSFLISLIFGVPTMIVMMVFMYGFSHRMQVIHLKNGINVTVMVSNAPIXXXX------XXXXXXXXXXXXXPVQFYGARYFYVQAYKSIKHGSANMDVLVVMATSVSYIYSFIVILVSMILRQDSSPQTFFETTPMLIVFLSLGRWLEHIAKGKTSEALSKLLSLQAFEATIIVND-----NQERKISXXXXXXXXXXXXXPGEKIPIDGRVVSGKSRCDESLITGESMSVEKIPGSDVIGGTLNISGMLIIRATLVGEDSALNQIVKLVEEAQTSKAPIQELADKVAGLFVPGVIICSMFTLLIWIAIGYTN----PNLLPGHSSINTDNTELIWKYAFQLAITVLSVACPCSLGLATPTAVMVGTGVGAINGILIKGGVPLEKMHQLDVIVFDKTGTITTGKPSVTNFVMCVENVTSQIRNCILLMLGAAESSSEHPIGKAILQYVRETCDINEMPQVVHSKSVSGFGLECSLK----LQSDMFVPDSEIDNVLVKINDFQENNLTENLKETSVKWRKINEPVEVVLYLGNRNMMKENHISIPDKLDELMSRDEDNGRTVVLMAIDKVLLAMISIADQVKKEAALVVYTLEKMGVEVFLLTGDNHKTATAIAKEIGIRNVFAEVLPSHKVAKIQQIQNMSKYKRSWLFSCCSKPSKLTNVAMVGDGINDSPALAQADVGIAIGTGTDVAVEAADVVLIRNSLLDVIAAMKLSKDTVRRIRQNFVAATMYNLIGIPIAAGALMPIGVVFMPWMA 3000
            NKET        + + KC ++I GMTC+SCV  IE  + + +G+ S L+ L++   EV Y+P+++  S IA+ I ++GF+A + +  +    I+E++++GMTC+SCV+ IES+L + +G+L   VAL T K   KFDP++I PRDI+  I ++GF   L  K ++  + DH  E I++WK SFLISLIF +P M +M+  M+  +H +   H  + + +  + S  P +         LS+ NL+  L   PVQF G  YFY+QAYK++KH +ANMDVL+V+ATSV++IYS IV++V++  +   +P TFF+T PML VF++LGRWLEHIAK KTSEALS+L+SLQA EAT+++ D       E ++ V+LV++GD+V+V PG K P+DGRV+ G+S  DESLITGE+M V K PGS VI G++N +G L+I AT VG D+ L+QIVKLVE+AQTSKAPIQ+ ADK++G FVP ++  S+ TL +WI IGY N        PG++  +    E+I ++AFQ AITVL +ACPCSLGLATPTAVMVGTGVGA NGILIKGG PLE  H++  +VFDKTGTIT G P V    + VE+      N +L ++G AES+SEHP+G A+++Y +E  +   +      ++V G G+ C +     L      PD++ + VLV+I+   E+++  ++  +       + P    + +GNR  M  N +++  + D LM+  E  GRT VL+A+D VL  +I+IAD VK EAAL +++L  MG+++ L+TGDN KTA  IA ++GI  VFAEVLPSHKVAK++Q+Q                    T VAMVGDGINDSPALA ADVGI IG+GTDVA+EAADVVLIRN LLDV+A++ LS+ TV+RIR NFV A +YNL+GIPIAAG  MP+G++  PWM 
Sbjct:  472 NKETPVHSKPEKRTVNKCFIQITGMTCASCVANIERNLRREEGIYSVLVALMAGKAEVRYNPEVLQPSGIAELIQELGFEASVLENYDDGTGILELLVRGMTCASCVHKIESRLMKTKGVLYSSVALATNKAHIKFDPEVIGPRDIMKIINDLGFSTSLVKKDRSASHLDHRVE-IQRWKRSFLISLIFCIPVMGLMVHMMFMENHYLMPHH--HNMTMEDIASYHPTMVLEYQIIPGLSIMNLVSLLLCIPVQFLGGWYFYIQAYKALKHRTANMDVLIVLATSVAFIYSLIVLIVAIFEKSKVNPITFFDTPPMLFVFIALGRWLEHIAKSKTSEALSRLISLQATEATVVILDPDNTVKSEEQVDVELVQRGDIVRVTPGGKFPVDGRVIEGQSMVDESLITGEAMPVSKKPGSSVIAGSINQNGSLLIAATHVGSDTTLSQIVKLVEDAQTSKAPIQQFADKLSGYFVPFIVAVSVLTLFVWIIIGYHNFEIVEKYFPGYNK-SISKGEVIVRFAFQAAITVLCIACPCSLGLATPTAVMVGTGVGAQNGILIKGGEPLEMAHKVKTVVFDKTGTITKGTPVVMQVKVLVES-NRMPSNKLLAIVGTAESNSEHPLGSAVIKYCKEVLNAETLGTCYDFQAVPGCGISCKVNNIEPLLHAANGPDNKRNAVLVQIDGQHEDSILPSITVSQNPSNGSSPPQTYSVLIGNREWMNRNFLTLTAETDSLMTEHEKKGRTAVLVAVDGVLCGLIAIADTVKPEAALAIHSLRSMGLDIVLMTGDNSKTAKTIAAQVGITKVFAEVLPSHKVAKVKQLQEQG-----------------TRVAMVGDGINDSPALAMADVGITIGSGTDVAIEAADVVLIRNDLLDVVASIDLSRKTVKRIRINFVFALIYNLVGIPIAAGVFMPVGLILQPWMG 1384

HSP 2 Score: 82.4185 bits (202), Expect = 4.303e-15
Identity = 53/176 (30.11%), Postives = 84/176 (47.73%), Query Frame = 1

Query:  295 ELFKCHMRIQGMTCSSCVHTIENQVLKLKGVKS----------------------ALINLLSTIGEVTYDPDLIMASDIADTIN-----DMGFDAEIFQF---KEHTKDIIEVMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKL 732
            +L +   +I+GM C SCV  IE+ +    GV S                      ALI  +  +   T+   L    ++A+T +     +     EIF     ++    +  + I+GMTC SCV +IE  +++  G+ S++V+L    G  ++DP + SP DI  AIE+MGFDA L
Sbjct:  273 DLIRAIFQIEGMHCKSCVVNIESNIGSQHGVSSIEVSLENKLAVIHFYSNITTSDALIQAIEALSPGTFKVSLCNHPELAETFSMQKNSEASCAKEIFSSPSNQDFCSKVTVINIEGMTCMSCVQSIEGLISKKPGVKSIQVSLVNNNGTVQYDPAVTSPEDIRAAIEDMGFDASL 448

HSP 3 Score: 71.2478 bits (173), Expect = 1.046e-11
Identity = 48/187 (25.67%), Postives = 86/187 (45.99%), Query Frame = 1

Query:  229 LCEAIENLGFLINKNKETDNTKELFKCHMRIQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMGFDAEIFQFKEHTKDIIE------------VMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKLAPKKTNK 753
            L EA+E++GF    +        +    +R   ++       I + + + KGV     +L   +  VT+ P ++    +   I  +  D+     K+ T   +E            + I+GMTC SC  TIE K+ +++G+  +KV+L +++ +  + P +I P DI   IEE GF A++  K   K
Sbjct:   62 LQEAVEDMGFESTLSYANPQPVPMDSTFLR---LSAEQSAEQIRSGLSQFKGVLDVKTSLEGKVACVTFIPSVVNPGLLIQKIPGLSLDS--MASKKTTSGSVESRSSVASDVLVKMKIEGMTCHSCTSTIEGKVGKLKGVQRIKVSLDSQEAQILYQPHLIKPEDIRTQIEEAGFIAQIKSKPPQK 243

HSP 4 Score: 68.9366 bits (167), Expect = 5.776e-11
Identity = 40/149 (26.85%), Postives = 74/149 (49.66%), Query Frame = 1

Query:  301 FKCHMRIQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMGFDAEIFQFKEHTKDIIEVMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKLAPKKT 747
            F   + ++GMTC+SCV TIE ++  + GV S  ++L      + YD  L     + + + DMGF++ +         +    ++ ++       I S L+Q +G+L VK +L  +     F P +++P  ++  I  +  D+ +A KKT
Sbjct:    8 FLAFIPVEGMTCNSCVQTIEQKIGSINGVHSIKVSLEGKNAAIIYDAKLQTPKALQEAVEDMGFESTLSYANPQPVPMDSTFLR-LSAEQSAEQIRSGLSQFKGVLDVKTSLEGKVACVTFIPSVVNPGLLIQKIPGLSLDS-MASKKT 154

[Close]

BLAST of Copper-transporting ATPase 1 vs. Ensembl Xenopus
Match: dhx34 (DEAH-box helicase 34 [Source:Xenbase;Acc:XB-GENE-1009178])

HSP 1 Score: 836.254 bits (2159), Expect = 0.000e+0
Identity = 451/935 (48.24%), Postives = 629/935 (67.27%), Query Frame = 1

Query:  271 NKETD-----NTKELFKCHMRIQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMGFDAEIFQFKEHTKDIIEVMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKLAPK-KTNKYNDHVGESIKKWKHSFLISLIFGVPTMIVMMVFMYGFSHRMQVIHLKNGINVTVMVSNAPIXXXX------XXXXXXXXXXXXXPVQFYGARYFYVQAYKSIKHGSANMDVLVVMATSVSYIYSFIVILVSMILRQDSSPQTFFETTPMLIVFLSLGRWLEHIAKGKTSEALSKLLSLQAFEATIIVND-----NQERKISXXXXXXXXXXXXXPGEKIPIDGRVVSGKSRCDESLITGESMSVEKIPGSDVIGGTLNISGMLIIRATLVGEDSALNQIVKLVEEAQTSKAPIQELADKVAGLFVPGVIICSMFTLLIWIAIGYTN----PNLLPGHSSINTDNTELIWKYAFQLAITVLSVACPCSLGLATPTAVMVGTGVGAINGILIKGGVPLEKMHQLDVIVFDKTGTITTGKPSVTNFVMCVENVTSQIRNCILLMLGAAESSSEHPIGKAILQYVRETCDINEMPQVVHSKSVSGFGLECSLK----LQSDMFVPDSEIDNVLVKINDFQENNLTENLKETSVKWRKINEPVEVVLYLGNRNMMKENHISIPDKLDELMSRDEDNGRTVVLMAIDKVLLAMISIADQVKKEAALVVYTLEKMGVEVFLLTGDNHKTATAIAKEIGIRNVFAEVLPSHKVAKIQQIQNMSKYKRSWLFSCCSKPSKLTNVAMVGDGINDSPALAQADVGIAIGTGTDVAVEAADVVLIRNSLLDVIAAMKLSKDTVRRIRQNFVAATMYNLIGIPIAAGALMPIGVVFMPWMA 3000
            NKET        + + KC ++I GMTC+SCV  IE  + + +G+ S L+ L++   EV Y+P+++  S IA+ I ++GF+A + +  +    I+E++++GMTC+SCV+ IES+L + +G+L   VAL T K   KFDP++I PRDI+  I ++GF   L  K ++  + DH  E I++WK SFLISLIF +P M +M+  M+  +H +   H  + + +  + S  P +         LS+ NL+  L   PVQF G  YFY+QAYK++KH +ANMDVL+V+ATSV++IYS IV++V++  +   +P TFF+T PML VF++LGRWLEHIAK KTSEALS+L+SLQA EAT+++ D       E ++ V+LV++GD+V+V PG K P+DGRV+ G+S  DESLITGE+M V K PGS VI G++N +G L+I AT VG D+ L+QIVKLVE+AQTSKAPIQ+ ADK++G FVP ++  S+ TL +WI IGY N        PG++  +    E+I ++AFQ AITVL +ACPCSLGLATPTAVMVGTGVGA NGILIKGG PLE  H++  +VFDKTGTIT G P V    + VE+      N +L ++G AES+SEHP+G A+++Y +E  +   +      ++V G G+ C +     L      PD++ + VLV+I+   E+++  ++  +       + P    + +GNR  M  N +++  + D LM+  E  GRT VL+A+D VL  +I+IAD VK EAAL +++L  MG+++ L+TGDN KTA  IA ++GI  VFAEVLPSHKVAK++Q+Q                    T VAMVGDGINDSPALA ADVGI IG+GTDVA+EAADVVLIRN LLDV+A++ LS+ TV+RIR NFV A +YNL+GIPIAAG  MP+G++  PWM 
Sbjct:  478 NKETPVHSKPEKRTVNKCFIQITGMTCASCVANIERNLRREEGIYSVLVALMAGKAEVRYNPEVLQPSGIAELIQELGFEASVLENYDDGTGILELLVRGMTCASCVHKIESRLMKTKGVLYSSVALATNKAHIKFDPEVIGPRDIMKIINDLGFSTSLVKKDRSASHLDHRVE-IQRWKRSFLISLIFCIPVMGLMVHMMFMENHYLMPHH--HNMTMEDIASYHPTMVLEYQIIPGLSIMNLVSLLLCIPVQFLGGWYFYIQAYKALKHRTANMDVLIVLATSVAFIYSLIVLIVAIFEKSKVNPITFFDTPPMLFVFIALGRWLEHIAKSKTSEALSRLISLQATEATVVILDPDNTVKSEEQVDVELVQRGDIVRVTPGGKFPVDGRVIEGQSMVDESLITGEAMPVSKKPGSSVIAGSINQNGSLLIAATHVGSDTTLSQIVKLVEDAQTSKAPIQQFADKLSGYFVPFIVAVSVLTLFVWIIIGYHNFEIVEKYFPGYNK-SISKGEVIVRFAFQAAITVLCIACPCSLGLATPTAVMVGTGVGAQNGILIKGGEPLEMAHKVKTVVFDKTGTITKGTPVVMQVKVLVES-NRMPSNKLLAIVGTAESNSEHPLGSAVIKYCKEVLNAETLGTCYDFQAVPGCGISCKVNNIEPLLHAANGPDNKRNAVLVQIDGQHEDSILPSITVSQNPSNGSSPPQTYSVLIGNREWMNRNFLTLTAETDSLMTEHEKKGRTAVLVAVDGVLCGLIAIADTVKPEAALAIHSLRSMGLDIVLMTGDNSKTAKTIAAQVGITKVFAEVLPSHKVAKVKQLQEQG-----------------TRVAMVGDGINDSPALAMADVGITIGSGTDVAIEAADVVLIRNDLLDVVASIDLSRKTVKRIRINFVFALIYNLVGIPIAAGVFMPVGLILQPWMG 1390

HSP 2 Score: 82.0333 bits (201), Expect = 4.729e-15
Identity = 53/176 (30.11%), Postives = 84/176 (47.73%), Query Frame = 1

Query:  295 ELFKCHMRIQGMTCSSCVHTIENQVLKLKGVKS----------------------ALINLLSTIGEVTYDPDLIMASDIADTIN-----DMGFDAEIFQF---KEHTKDIIEVMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKL 732
            +L +   +I+GM C SCV  IE+ +    GV S                      ALI  +  +   T+   L    ++A+T +     +     EIF     ++    +  + I+GMTC SCV +IE  +++  G+ S++V+L    G  ++DP + SP DI  AIE+MGFDA L
Sbjct:  273 DLIRAIFQIEGMHCKSCVVNIESNIGSQHGVSSIEVSLENKLAVIHFYSNITTSDALIQAIEALSPGTFKVSLCNHPELAETFSMQKNSEASCAKEIFSSPSNQDFCSKVTVINIEGMTCMSCVQSIEGLISKKPGVKSIQVSLVNNNGTVQYDPAVTSPEDIRAAIEDMGFDASL 448

HSP 3 Score: 71.2478 bits (173), Expect = 1.021e-11
Identity = 48/187 (25.67%), Postives = 86/187 (45.99%), Query Frame = 1

Query:  229 LCEAIENLGFLINKNKETDNTKELFKCHMRIQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMGFDAEIFQFKEHTKDIIE------------VMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKLAPKKTNK 753
            L EA+E++GF    +        +    +R   ++       I + + + KGV     +L   +  VT+ P ++    +   I  +  D+     K+ T   +E            + I+GMTC SC  TIE K+ +++G+  +KV+L +++ +  + P +I P DI   IEE GF A++  K   K
Sbjct:   62 LQEAVEDMGFESTLSYANPQPVPMDSTFLR---LSAEQSAEQIRSGLSQFKGVLDVKTSLEGKVACVTFIPSVVNPGLLIQKIPGLSLDS--MASKKTTSGSVESRSSVASDVLVKMKIEGMTCHSCTSTIEGKVGKLKGVQRIKVSLDSQEAQILYQPHLIKPEDIRTQIEEAGFIAQIKSKPPQK 243

HSP 4 Score: 69.707 bits (169), Expect = 2.793e-11
Identity = 43/157 (27.39%), Postives = 78/157 (49.68%), Query Frame = 1

Query:  277 ETDNTKELFKCHMRIQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMGFDAEIFQFKEHTKDIIEVMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKLAPKKT 747
            ETD+    F   + ++GMTC+SCV TIE ++  + GV S  ++L      + YD  L     + + + DMGF++ +         +    ++ ++       I S L+Q +G+L VK +L  +     F P +++P  ++  I  +  D+ +A KKT
Sbjct:    2 ETDS--RAFLAFIPVEGMTCNSCVQTIEQKIGSINGVHSIKVSLEGKNAAIIYDAKLQTPKALQEAVEDMGFESTLSYANPQPVPMDSTFLR-LSAEQSAEQIRSGLSQFKGVLDVKTSLEGKVACVTFIPSVVNPGLLIQKIPGLSLDS-MASKKT 154

[Close]

BLAST of Copper-transporting ATPase 1 vs. Ensembl Xenopus
Match: dhx34 (DEAH-box helicase 34 [Source:Xenbase;Acc:XB-GENE-1009178])

HSP 1 Score: 835.099 bits (2156), Expect = 0.000e+0
Identity = 474/991 (47.83%), Postives = 663/991 (66.90%), Query Frame = 1

Query:  271 NKETD-----NTKELFKCHMRIQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMGFDAEIFQFKEHTKDIIEVMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKLAPK-KTNKYNDHVGESIKKWKHSFLISLIFGVPTMIVMMVFMYGFSHRMQVIHLKNGINVTVMVSNAPIXXXXX------XXXXXXXXXXXXPVQFYGARYFYVQAYKSIKHGSANMDVLVVMATSVSYIYSFIVILVSMILRQDSSPQTFFETTPMLIVFLSLGRWLEHIAKGKTSEALSKLLSLQAFEATIIVND-----NQERKISXXXXXXXXXXXXXPGEKIPIDGRVVSGKSRCDESLITGESMSVEKIPGSDVIGGTLNISGMLIIRATLVGEDSALNQIVKLVEEAQTSKAPIQELADKVAGLFVPGVIICSMFTLLIWIAIGYTN----PNLLPGHSSINTDNTELIWKYAFQLAITVLSVACPCSLGLATPTAVMVGTGVGAINGILIKGGVPLEKMHQLDVIVFDKTGTITTGKPSVTNFVMCVENVTSQIRNCILLMLGAAESSSEHPIGKAILQYVRETCDINEMPQVVHSKSVSGFGLECSLK----LQSDMFVPDSEIDNVLVKINDFQENNLTENLKETSVKWRKINEPVEVV-LYLGNRNMMKENHISIPDKLDELMSRDEDNGRTVVLMAIDKVLLAMISIADQVKKEAALVVYTLEKMGVEVFLLTGDNHKTATAIAKEIGIRNVFAEVLPSHKVAKIQQIQNMSKYKRSWLFSCCSKPSKLTNVAMVGDGINDSPALAQADVGIAIGTGTDVAVEAADVVLIRNSLLDVIAAMKLSKDTVRRIRQNFVAATMYNLIGIPIAAGALMPIGVVFMPWMASVAMAASSICVVCXXXXXXXXXXPNEDQLANQEFKNHLECLKYGDMEVGVNLGKD 3165
            NKET        + + KC ++I GMTC+SCV  IE  + + +G+ S L+ L++   EV Y+P+++  S IA+ I ++GF+A + +  +    I+E++++GMTC+SCV+ IES+L + +G+L   VAL T K   KFDP++I PRDI+  I ++GF   L  K ++  + DH  E I++WK SFLISLIF +P M +M+  M+  +H +   H  + + +  + S  P +          S+ NL+  L   PVQF G  YFY+QAYK++KH +ANMDVL+V+ATSV++IYS IV++V++  +   +P TFF+T PML VF++LGRWLEHIAK KTSEALS+L+SLQA EAT+++ D       E ++ V+LV++GD+V+V PG K P+DGRV+ G+S  DESLITGE+M V K PGS VI G++N +G L+I AT VG D+ L+QIVKLVE+AQTSKAPIQ+ ADK++G FVP ++  S+ TL +WI IGY N        PG++  +    E+I ++AFQ AITVL +ACPCSLGLATPTAVMVGTGVGA NGILIKGG PLE  H++  +VFDKTGTIT G P V    + VE+      N +L ++G AES+SEHP+G A+++Y +E  +   +      ++V G G+ C +     L      PD++ + VLV+I+   E+++   L   +V     + P +   + +GNR  M  N +++  + D LM+  E  GRT VL+A+D VL  +I+IAD VK EAAL +++L  MG+++ L+TGDN KTA  IA ++GI  VFAEVLPSHKVAK++Q+Q                    T VAMVGDGINDSPALA ADVGI IG+GTDVA+EAADVVLIRN LLDV+A++ LS+ TV+RIR NFV A +YNL+GIPIAAG  MP+G++  PWM S AMAASS+ VV  SLLLKL++KP+ ++L  Q  +  +      D+ V + L ++
Sbjct:  435 NKETPVHSKPEKRTVNKCFIQITGMTCASCVANIERNLRREEGIYSVLVALMAGKAEVRYNPEVLQPSGIAELIQELGFEASVLENYDDGTGILELLVRGMTCASCVHKIESRLMKTKGVLYSSVALATNKAHIKFDPEVIGPRDIMKIINDLGFSTSLVKKDRSASHLDHRVE-IQRWKRSFLISLIFCIPVMGLMVHMMFMENHYLMPHH--HNMTMEDIASYHPTMVLEYQIIPGLSIMNLVSLLLCIPVQFLGGWYFYIQAYKALKHRTANMDVLIVLATSVAFIYSLIVLIVAIFEKSKVNPITFFDTPPMLFVFIALGRWLEHIAKSKTSEALSRLISLQATEATVVILDPDNTVKSEEQVDVELVQRGDIVRVTPGGKFPVDGRVIEGQSMVDESLITGEAMPVSKKPGSSVIAGSINQNGSLLIAATHVGSDTTLSQIVKLVEDAQTSKAPIQQFADKLSGYFVPFIVAVSVLTLFVWIIIGYHNFEIVEKYFPGYNK-SISKGEVIVRFAFQAAITVLCIACPCSLGLATPTAVMVGTGVGAQNGILIKGGEPLEMAHKVKTVVFDKTGTITKGTPVVMQVKVLVES-NRMPSNKLLAIVGTAESNSEHPLGSAVIKYCKEVLNAETLGTCYDFQAVPGCGISCKVNNIEPLLHAANGPDNKRNAVLVQIDGQHEDSI---LPSITVSQNPSSSPPQTYSVLIGNREWMNRNFLTLTAETDSLMTEHEKKGRTAVLVAVDGVLCGLIAIADTVKPEAALAIHSLRSMGLDIVLMTGDNSKTAKTIAAQVGITKVFAEVLPSHKVAKVKQLQEQG-----------------TRVAMVGDGINDSPALAMADVGITIGSGTDVAIEAADVVLIRNDLLDVVASIDLSRKTVKRIRINFVFALIYNLVGIPIAAGVFMPVGLILQPWMGSAAMAASSVSVVFSSLLLKLYRKPSREKL-EQRVQGQMRQKSLSDISVHIGLTEN 1399

HSP 2 Score: 93.9745 bits (232), Expect = 1.112e-18
Identity = 59/178 (33.15%), Postives = 89/178 (50.00%), Query Frame = 1

Query:  313 MRIQGMTCSSCVHTIENQVLKLKGVKS----------------------ALINLLSTIGEVTYDPDLIMASDIADTIN-----DMGFDAEIFQF---KEHTKDIIEVMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKLAPKKTNKY 756
            M+I+GMTC SC  TIE +V KLKGV+                       ALI  +  +   T+   L    ++A+T +     +     EIF     ++    +  + I+GMTC SCV +IE  +++  G+ S++V+L    G  ++DP + SP DI  AIE+MGFDA L  K +  Y
Sbjct:  173 MKIEGMTCHSCTSTIEGKVGKLKGVQRIKVSLENKLAVIHFYSNITTSDALIQAIEALSPGTFKVSLCNHPELAETFSMQKNSEASCAKEIFSSPSNQDFCSKVTVINIEGMTCMSCVQSIEGLISKKPGVKSIQVSLVNNNGTVQYDPAVTSPEDIRAAIEDMGFDASLLGKYSFFY 350

HSP 3 Score: 70.0922 bits (170), Expect = 2.321e-11
Identity = 43/157 (27.39%), Postives = 78/157 (49.68%), Query Frame = 1

Query:  277 ETDNTKELFKCHMRIQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMGFDAEIFQFKEHTKDIIEVMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKLAPKKT 747
            ETD+    F   + ++GMTC+SCV TIE ++  + GV S  ++L      + YD  L     + + + DMGF++ +         +    ++ ++       I S L+Q +G+L VK +L  +     F P +++P  ++  I  +  D+ +A KKT
Sbjct:    2 ETDS--RAFLAFIPVEGMTCNSCVQTIEQKIGSINGVHSIKVSLEGKNAAIIYDAKLQTPKALQEAVEDMGFESTLSYANPQPVPMDSTFLR-LSAEQSAEQIRSGLSQFKGVLDVKTSLEGKVACVTFIPSVVNPGLLIQKIPGLSLDS-MASKKT 154

[Close]

BLAST of Copper-transporting ATPase 1 vs. Ensembl Xenopus
Match: dhx34 (DEAH-box helicase 34 [Source:Xenbase;Acc:XB-GENE-1009178])

HSP 1 Score: 831.632 bits (2147), Expect = 0.000e+0
Identity = 455/955 (47.64%), Postives = 635/955 (66.49%), Query Frame = 1

Query:  238 AIENLGFLINKNKETDNTK---ELF-----------KCHMRIQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMGFDAEIFQFKEHTKDIIEVMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKLAPK-KTNKYNDHVGESIKKWKHSFLISLIFGVPTMIVMMVFMYGFSHRMQVIHLKNGINVTVMVSNAPIXXXX------XXXXXXXXXXXXXPVQFYGARYFYVQAYKSIKHGSANMDVLVVMATSVSYIYSFIVILVSMILRQDSSPQTFFETTPMLIVFLSLGRWLEHIAKGKTSEALSKLLSLQAFEATIIVND-----NQERKISXXXXXXXXXXXXXPGEKIPIDGRVVSGKSRCDESLITGESMSVEKIPGSDVIGGTLNISGMLIIRATLVGEDSALNQIVKLVEEAQTSKAPIQELADKVAGLFVPGVIICSMFTLLIWIAIGYTN----PNLLPGHSSINTDNTELIWKYAFQLAITVLSVACPCSLGLATPTAVMVGTGVGAINGILIKGGVPLEKMHQLDVIVFDKTGTITTGKPSVTNFVMCVENVTSQIRNCILLMLGAAESSSEHPIGKAILQYVRETCDINEMPQVVHSKSVSGFGLECSLK----LQSDMFVPDSEIDNVLVKINDFQENNLTENLKETSVKWRKINEPVEVVLYLGNRNMMKENHISIPDKLDELMSRDEDNGRTVVLMAIDKVLLAMISIADQVKKEAALVVYTLEKMGVEVFLLTGDNHKTATAIAKEIGIRNVFAEVLPSHKVAKIQQIQNMSKYKRSWLFSCCSKPSKLTNVAMVGDGINDSPALAQADVGIAIGTGTDVAVEAADVVLIRNSLLDVIAAMKLSKDTVRRIRQNFVAATMYNLIGIPIAAGALMPIGVVFMPWMA 3000
            AIE++GF  +  +E    K   EL+           KC ++I GMTC+SCV  IE  + + +G+ S L+ L++   EV Y+P+++  S IA+ I ++GF+A + +  +    I+E++++GMTC+SCV+ IES+L + +G+L   VAL T K   KFDP++I PRDI+  I ++GF   L  K ++  + DH  E I++WK SFLISLIF +P M +M+  M+  +H +   H  + + +  + S  P +         LS+ NL+  L   PVQF G  YFY+QAYK++KH +ANMDVL+V+ATSV++IYS IV++V++  +   +P TFF+T PML VF++LGRWLEHIAK KTSEALS+L+SLQA EAT+++ D       E ++ V+LV++GD+V+V PG K P+DGRV+ G+S  DESLITGE+M V K PGS VI G++N +G L+I AT VG D+ L+QIVKLVE+AQTSKAPIQ+ ADK++G FVP ++  S+ TL +WI IGY N        PG++  +    E+I ++AFQ AITVL +ACPCSLGLATPTAVMVGTGVGA NGILIKGG PLE  H++  +VFDKTGTIT G P V    + VE+      N +L ++G AES+SEHP+G A+++Y +E  +   +      ++V G G+ C +     L      PD++ + VLV+I+   E+++   +  +  ++            +GNR  M  N +++  + D LM+  E  GRT VL+A+D VL  +I+IAD VK EAAL +++L  MG+++ L+TGDN KTA  IA ++GI  VFAEVLPSHKVAK++Q+Q                    T VAMVGDGINDSPALA ADVGI IG+GTDVA+EAADVVLIRN LLDV+A++ LS+ TV+RIR NFV A +YNL+GIPIAAG  MP+G++  PWM 
Sbjct:  438 AIEDMGFDQHVAREPLVGKFDFELYCSCKPEKRTVNKCFIQITGMTCASCVANIERNLRREEGIYSVLVALMAGKAEVRYNPEVLQPSGIAELIQELGFEASVLENYDDGTGILELLVRGMTCASCVHKIESRLMKTKGVLYSSVALATNKAHIKFDPEVIGPRDIMKIINDLGFSTSLVKKDRSASHLDHRVE-IQRWKRSFLISLIFCIPVMGLMVHMMFMENHYLMPHH--HNMTMEDIASYHPTMVLEYQIIPGLSIMNLVSLLLCIPVQFLGGWYFYIQAYKALKHRTANMDVLIVLATSVAFIYSLIVLIVAIFEKSKVNPITFFDTPPMLFVFIALGRWLEHIAKSKTSEALSRLISLQATEATVVILDPDNTVKSEEQVDVELVQRGDIVRVTPGGKFPVDGRVIEGQSMVDESLITGEAMPVSKKPGSSVIAGSINQNGSLLIAATHVGSDTTLSQIVKLVEDAQTSKAPIQQFADKLSGYFVPFIVAVSVLTLFVWIIIGYHNFEIVEKYFPGYNK-SISKGEVIVRFAFQAAITVLCIACPCSLGLATPTAVMVGTGVGAQNGILIKGGEPLEMAHKVKTVVFDKTGTITKGTPVVMQVKVLVES-NRMPSNKLLAIVGTAESNSEHPLGSAVIKYCKEVLNAETLGTCYDFQAVPGCGISCKVNNIEPLLHAANGPDNKRNAVLVQIDGQHEDSILNVVNLSQFRF-----------LIGNREWMNRNFLTLTAETDSLMTEHEKKGRTAVLVAVDGVLCGLIAIADTVKPEAALAIHSLRSMGLDIVLMTGDNSKTAKTIAAQVGITKVFAEVLPSHKVAKVKQLQEQG-----------------TRVAMVGDGINDSPALAMADVGITIGSGTDVAIEAADVVLIRNDLLDVVASIDLSRKTVKRIRINFVFALIYNLVGIPIAAGVFMPVGLILQPWMG 1359

HSP 2 Score: 80.4925 bits (197), Expect = 1.591e-14
Identity = 52/177 (29.38%), Postives = 84/177 (47.46%), Query Frame = 1

Query:  295 ELFKCHMRIQGMTCSSCVHTIENQVLKLKGVKS----------------------ALINLLSTIGEVTYDPDLIMASDIADTIN-----DMGFDAEIFQF---KEHTKDIIEVMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKLA 735
            +L +   +I+GM C SCV  IE+ +    GV S                      ALI  +  +   T+   L    ++A+T +     +     EIF     ++    +  + I+GMTC SCV +IE  +++  G+ S++V+L    G  ++DP + SP DI  AIE+MGFD  +A
Sbjct:  273 DLIRAIFQIEGMHCKSCVVNIESNIGSQHGVSSIEVSLENKLAVIHFYSNITTSDALIQAIEALSPGTFKVSLCNHPELAETFSMQKNSEASCAKEIFSSPSNQDFCSKVTVINIEGMTCMSCVQSIEGLISKKPGVKSIQVSLVNNNGTVQYDPAVTSPEDIRAAIEDMGFDQHVA 449

HSP 3 Score: 70.8626 bits (172), Expect = 1.213e-11
Identity = 48/187 (25.67%), Postives = 86/187 (45.99%), Query Frame = 1

Query:  229 LCEAIENLGFLINKNKETDNTKELFKCHMRIQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMGFDAEIFQFKEHTKDIIE------------VMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKLAPKKTNK 753
            L EA+E++GF    +        +    +R   ++       I + + + KGV     +L   +  VT+ P ++    +   I  +  D+     K+ T   +E            + I+GMTC SC  TIE K+ +++G+  +KV+L +++ +  + P +I P DI   IEE GF A++  K   K
Sbjct:   62 LQEAVEDMGFESTLSYANPQPVPMDSTFLR---LSAEQSAEQIRSGLSQFKGVLDVKTSLEGKVACVTFIPSVVNPGLLIQKIPGLSLDS--MASKKTTSGSVESRSSVASDVLVKMKIEGMTCHSCTSTIEGKVGKLKGVQRIKVSLDSQEAQILYQPHLIKPEDIRTQIEEAGFIAQIKSKPPQK 243

HSP 4 Score: 69.707 bits (169), Expect = 3.024e-11
Identity = 43/157 (27.39%), Postives = 78/157 (49.68%), Query Frame = 1

Query:  277 ETDNTKELFKCHMRIQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMGFDAEIFQFKEHTKDIIEVMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKLAPKKT 747
            ETD+    F   + ++GMTC+SCV TIE ++  + GV S  ++L      + YD  L     + + + DMGF++ +         +    ++ ++       I S L+Q +G+L VK +L  +     F P +++P  ++  I  +  D+ +A KKT
Sbjct:    2 ETDS--RAFLAFIPVEGMTCNSCVQTIEQKIGSINGVHSIKVSLEGKNAAIIYDAKLQTPKALQEAVEDMGFESTLSYANPQPVPMDSTFLR-LSAEQSAEQIRSGLSQFKGVLDVKTSLEGKVACVTFIPSVVNPGLLIQKIPGLSLDS-MASKKT 154

[Close]

BLAST of Copper-transporting ATPase 1 vs. Ensembl Mouse
Match: Atp7b (ATPase, Cu++ transporting, beta polypeptide [Source:MGI Symbol;Acc:MGI:103297])

HSP 1 Score: 828.935 bits (2140), Expect = 0.000e+0
Identity = 445/908 (49.01%), Postives = 607/908 (66.85%), Query Frame = 1

Query:  304 KCHMRIQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMGFDAEIFQFKEHTKDIIEVMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKLAPKKTNKYN-DHVGESIKKWKHSFLISLIFGVPTMIVMMVFMYGFSHRMQVIHLKNGINVTVMVSNAPIXXXXXXXXXXXXXXXXXPVQFYGARYFYVQAYKSIKHGSANMDVLVVMATSVSYIYSFIVILVSMILRQDSSPQTFFETTPMLIVFLSLGRWLEHIAKGKTSEALSKLLSLQAFEATIIV--NDN---QERKISXXXXXXXXXXXXXPGEKIPIDGRVVSGKSRCDESLITGESMSVEKIPGSDVIGGTLNISGMLIIRATLVGEDSALNQIVKLVEEAQTSKAPIQELADKVAGLFVPGVIICSMFTLLIWIAIGYTNPNLLPGH---SSINTDNTELIWKYAFQLAITVLSVACPCSLGLATPTAVMVGTGVGAINGILIKGGVPLEKMHQLDVIVFDKTGTITTGKPSVTNFVMCVENVTSQIRNCILLMLGAAESSSEHPIGKAILQYVRETCDINEMPQVVHSKSVSGFGLECSLKLQSDMFVPDSEIDNVLVKINDFQENNLTENLKETSVKWRKINEPVEVVLYLGNRNMMKENHISIPDKLDELMSRDEDNGRTVVLMAIDKVLLAMISIADQVKKEAALVVYTLEKMGVEVFLLTGDNHKTATAIAKEIGIRNVFAEVLPSHKVAKIQQIQNMSKYKRSWLFSCCSKPSKLTNVAMVGDGINDSPALAQADVGIAIGTGTDVAVEAADVVLIRNSLLDVIAAMKLSKDTVRRIRQNFVAATMYNLIGIPIAAGALMPIGVVFMPWMA 3000
            KC ++I+GMTC+SCV  IE  + +  G+ S L+ L+S   EV YDP++I +  IA  I D+GF+A + +    ++  IE++I GMTC+SCV+ IESKL +  GI    VAL T K   KFDP+I+ PRDI+  IEE+GF A LA +  N ++ DH  E IK+WK SFL SL+FG+P M +M+  +   S   + + L + I   + V N                     VQF G  YFYVQAYKS++H SANMDVL+V+AT+++Y YS ++++V++  + + SP TFF+T PML VF++LGRWLEH+AK KTSEAL+KL+SLQA EAT++    DN   +E ++ ++LV++GD++KV+PG K P+DG+V+ G +  DESLITGE+M V K PGS VI G++N  G ++++AT VG D+ L QIVKLVEEAQ SKAPIQ+LAD+ +G FVP +II S  TL++WI IG+ +  ++  +    S +   TE+I ++AFQ +ITVL +ACPCSLGLATPTAVMVGTGV A NG+LIKGG PLE  H++  ++FDKTGTIT G P V  F++  +  T  +R  +L ++G AE+SSEHP+G A+ +Y +E      +      ++V G G+ C +          S ++ +L + +D   + +      T     +   P    + +GNR  M+ N ++I   + + M+  E  G+T +L+AID VL  MI+IAD VK EAAL +YTL+ MGV+V L+TGDN KTA AIA ++GI  VFAEVLPSHKVAK+Q++QN  K                  VAMVGDG+NDSPALAQADVGIAIGTGTDVA+EAADVVLIRN LLDV+A++ LSK TVRRIR N V A +YN++GIPIAAG  MPIG+V  PWM 
Sbjct:  376 KCFVQIKGMTCASCVSNIERSLQRHAGILSVLVALMSGKAEVKYDPEIIQSPRIAQLIQDLGFEASVMEDNTVSEGDIELIITGMTCASCVHNIESKLTRTNGITYASVALATSKAHVKFDPEIVGPRDIIKIIEEIGFHASLAQRNPNAHHLDHKTE-IKQWKKSFLCSLVFGIPVMGLMVYMLIPSSTPQETMVLDHNIIPGLSVLNLIFFILCTF------------VQFLGGWYFYVQAYKSLRHRSANMDVLIVLATTIAYAYSLVILVVAVAEKAEKSPVTFFDTPPMLFVFIALGRWLEHVAKSKTSEALAKLMSLQATEATVVTLGEDNLILREEQVPMELVQRGDVIKVVPGGKFPVDGKVLEGNTMADESLITGEAMPVTKKPGSIVIAGSINAHGSVLLKATHVGNDTTLAQIVKLVEEAQMSKAPIQQLADRFSGYFVPFIIIISTLTLVVWIVIGFVDFGVVQKYFPSPSKHISQTEVIIRFAFQTSITVLCIACPCSLGLATPTAVMVGTGVAAQNGVLIKGGKPLEMAHKIKTVMFDKTGTITHGVPRVMRFLLLADVATLPLRK-VLAVVGTAEASSEHPLGVAVTKYCKEELGTETLGYSTDFQAVPGCGISCKV----------SNVEGILAR-SDLTAHPVGVGNPPTG----EGAGPQTFSVLIGNREWMRRNGLTISSDISDAMTDHEMKGQTAILVAIDGVLCGMIAIADAVKPEAALAIYTLKSMGVDVALITGDNRKTARAIATQVGINKVFAEVLPSHKVAKVQELQNEGK-----------------KVAMVGDGVNDSPALAQADVGIAIGTGTDVAIEAADVVLIRNDLLDVVASIHLSKRTVRRIRVNLVLALIYNMVGIPIAAGVFMPIGIVLQPWMG 1237

HSP 2 Score: 102.449 bits (254), Expect = 2.437e-21
Identity = 54/163 (33.13%), Postives = 91/163 (55.83%), Query Frame = 1

Query:  319 IQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMGFDAEIFQFKEHT---------KDIIEVMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDA---------KLAPKKTNK 753
            I GMTC SCV +IE+++  LKG+ +  ++L      V Y P ++    I   I DMGF+A   + K  +         + ++++ ++GMTC SCV +IE K+ ++QG++ +KV+L+ ++    + P +I P D+ D I +MGF+A         +L P   NK
Sbjct:   62 ILGMTCHSCVKSIEDRISSLKGIVNIKVSLEQGSATVRYVPSVMNLQQICLQIEDMGFEASAAEGKAASWPSRSSPAQEAVVKLRVEGMTCQSCVSSIEGKIRKLQGVVRIKVSLSNQEAVITYQPYLIQPEDLRDHICDMGFEAAIKNRTAPLRLGPIDVNK 224

HSP 3 Score: 62.3882 bits (150), Expect = 4.153e-9
Identity = 31/94 (32.98%), Postives = 53/94 (56.38%), Query Frame = 1

Query:  229 LCEAIENLGFLINKNKETDNTKELFKCHMRIQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMGFDAEIFQ 510
            + + I++LGF    +   DNT       + I GMTC+SCVH IE+++ +  G+  A + L ++   V +DP+++   DI   I ++GF A + Q
Sbjct:  429 IAQLIQDLGF--EASVMEDNTVSEGDIELIITGMTCASCVHNIESKLTRTNGITYASVALATSKAHVKFDPEIVGPRDIIKIIEEIGFHASLAQ 520

HSP 4 Score: 56.225 bits (134), Expect = 2.760e-7
Identity = 26/72 (36.11%), Postives = 45/72 (62.50%), Query Frame = 1

Query:  541 VMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKLAPKKTNKY 756
            V I GMTC SCV +IE +++ ++GI+++KV+L       ++ P +++ + I   IE+MGF+A  A  K   +
Sbjct:   60 VNILGMTCHSCVKSIEDRISSLKGIVNIKVSLEQGSATVRYVPSVMNLQQICLQIEDMGFEASAAEGKAASW 131

[Close]

BLAST of Copper-transporting ATPase 1 vs. Ensembl Mouse
Match: Atp7a (ATPase, Cu++ transporting, alpha polypeptide [Source:MGI Symbol;Acc:MGI:99400])

HSP 1 Score: 828.165 bits (2138), Expect = 0.000e+0
Identity = 467/974 (47.95%), Postives = 637/974 (65.40%), Query Frame = 1

Query:  226 TLCEAIENLGF-----------------------LINKNKETDN--TKELFKCHMRIQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMGFDAEIFQFKEHTKDIIEVMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKLAPK-KTNKYNDHVGESIKKWKHSFLISLIFGVPTMIVMMVFMYGFSHRMQVIHLKNGINVTVMVSNAPIXXXXX------XXXXXXXXXXXXPVQFYGARYFYVQAYKSIKHGSANMDVLVVMATSVSYIYSFIVILVSMILRQDSSPQTFFETTPMLIVFLSLGRWLEHIAKGKTSEALSKLLSLQAFEATIIVNDNQ-----ERKISXXXXXXXXXXXXXPGEKIPIDGRVVSGKSRCDESLITGESMSVEKIPGSDVIGGTLNISGMLIIRATLVGEDSALNQIVKLVEEAQTSKAPIQELADKVAGLFVPGVIICSMFTLLIWIAIGYTN----PNLLPGHSSINTDNTELIWKYAFQLAITVLSVACPCSLGLATPTAVMVGTGVGAINGILIKGGVPLEKMHQLDVIVFDKTGTITTGKPSVTNFVMCVENVTSQI-RNCILLMLGAAESSSEHPIGKAILQYVRETCDINEMPQVVHSKSVSGFGLEC------SLKLQSDMFVPDSEIDNV-LVKINDFQENNLTENLKETSVKWRKINEPVEVVLYLGNRNMMKENHISIPDKLDELMSRDEDNGRTVVLMAIDKVLLAMISIADQVKKEAALVVYTLEKMGVEVFLLTGDNHKTATAIAKEIGIRNVFAEVLPSHKVAKIQQIQNMSKYKRSWLFSCCSKPSKLTNVAMVGDGINDSPALAQADVGIAIGTGTDVAVEAADVVLIRNSLLDVIAAMKLSKDTVRRIRQNFVAATMYNLIGIPIAAGALMPIGVVFMPWMA 3000
            TL EAIE++GF                       L+  + E +N  T    KC++++ GMTC+SCV  IE  + + +G+ S L+ L++   EV Y+P +I    IA+ I ++GF A + +       I+E++++GMTC+SCV+ IES L + +GI    VAL T K   K+DP+II PRDI+  I  +GF+A L  K ++  + DH  E IK+W+ SFL+SL F +P M  +MV+M    H +  +H    ++   M++    +F         S+ NLL  L   PVQF G  YFY+QAYK++KH +ANMDVL+V+AT++++ YS +++LV+M  R   +P TFF+T PML VF++LGRWLEHIAKGKTSEAL+KL+SLQA EATI+  +++     E ++ V+LV++GD++KV+PG K P+DGRV+ G S  DESLITGE+M V K PGS VI G++N +G L+IRAT VG D+ L+QIVKLVEEAQTSKAPIQ+ ADK++G FVP +++ S+ TLL+WI IG+ N        PG++  +   TE I ++AFQ +ITVL +ACPCSLGLATPTAVMVGTGVGA NGILIKGG PLE  H++ V+VFDKTGTIT G P V    + VE  +++I RN IL ++G AES+SEHP+G A+ +Y ++  D   +      + V G G+ C       L  +S++ + ++ I N  LV+I+   E + T +               +  + +GNR  M  N + I + +DE M   E  GRT VL+ ID  L  +I+IAD VK EA L V+ L+ MG+EV L+TGDN KTA +IA ++GI  VFAEVLPSHKVAK++Q+Q   K                  VAMVGDGINDSPALA A+VGIAIGTGTDVA+EAADVVLIRN LLDV+A++ LS+ TV+RIR NFV A +YNL+GIPIAAG  +PIG+V  PWM 
Sbjct:  430 TLREAIEDMGFDAALPADMKEPLVVIAQPSLETPLLPSSNELENVMTSVQNKCYIQVSGMTCASCVANIERNLRREEGIYSVLVALMAGKAEVRYNPAVIQPRVIAEFIRELGFGAMVMENAGEGNGILELVVRGMTCASCVHKIESTLTKHKGIFYCSVALATNKAHIKYDPEIIGPRDIIHTIGSLGFEASLVKKDRSANHLDHKRE-IKQWRGSFLVSLFFCIPVM-GLMVYMMVMDHHLATLHHNQNMSNEEMINMHSAMFLERQILPGLSIMNLLSLLLCLPVQFCGGWYFYIQAYKALKHKTANMDVLIVLATTIAFAYSLVILLVAMFERAKVNPITFFDTPPMLFVFIALGRWLEHIAKGKTSEALAKLISLQATEATIVTLNSENLLLSEEQVDVELVQRGDIIKVVPGGKFPVDGRVIEGHSMVDESLITGEAMPVAKKPGSTVIAGSINQNGSLLIRATHVGADTTLSQIVKLVEEAQTSKAPIQQFADKLSGYFVPFIVLVSIVTLLVWIIIGFQNFEIVETYFPGYNR-SISRTETIIRFAFQASITVLCIACPCSLGLATPTAVMVGTGVGAQNGILIKGGEPLEMAHKVKVVVFDKTGTITHGTPVVNQVKVLVE--SNKISRNKILAIVGTAESNSEHPLGAAVTKYCKKELDTETLGTCTDFQVVPGCGISCKVTNIEGLLHKSNLKIEENNIKNASLVQIDAINEQSSTSSSMIIDAHLSNAVNTQQYKVLIGNREWMIRNGLVISNDVDESMIEHERRGRTAVLVTIDDELCGLIAIADTVKPEAELAVHILKSMGLEVVLMTGDNSKTARSIASQVGITKVFAEVLPSHKVAKVKQLQEEGK-----------------RVAMVGDGINDSPALAMANVGIAIGTGTDVAIEAADVVLIRNDLLDVVASIDLSRKTVKRIRINFVFALIYNLVGIPIAAGVFLPIGLVLQPWMG 1381

HSP 2 Score: 100.138 bits (248), Expect = 1.289e-20
Identity = 56/165 (33.94%), Postives = 83/165 (50.30%), Query Frame = 1

Query:  313 MRIQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMGFDA---------------------------EIFQFKEHTKDIIEVMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDA 726
            + I GMTC+SCV +IE  + K  GVKS  ++L ++ G + +DP L     + + I DMGFDA                           E+       ++   + + GMTC+SCV  IE  L + +GI SV VAL   K + +++P +I PR I + I E+GF A
Sbjct:  381 ININGMTCNSCVQSIEGVISKKPGVKSIHVSLANSTGTIEFDPLLTSPETLREAIEDMGFDAALPADMKEPLVVIAQPSLETPLLPSSNELENVMTSVQNKCYIQVSGMTCASCVANIERNLRREEGIYSVLVALMAGKAEVRYNPAVIQPRVIAEFIRELGFGA 545

HSP 3 Score: 77.411 bits (189), Expect = 1.103e-13
Identity = 63/190 (33.16%), Postives = 94/190 (49.47%), Query Frame = 1

Query:  226 TLCEAIENLGF---LINKNKETDNTKELFKCHMRIQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMGFDAEIFQFK-----EH-TKDIIEVM----IQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKLAPKKTNKY 756
            TL EAI+++GF   L N N     T  +F   + +         H I++ +LK KGV    I+       VT  P ++ AS I + + D+  D    + K     EH T    EVM    ++GMTC SC  TIE K+ ++QG+  +KV+L  ++    F P +I+  +I   IE +GF A +  KK  KY
Sbjct:   61 TLQEAIDDMGFDALLHNANPLPVLTNTVF---LTVTAPLTLPWDH-IQSTLLKTKGVTGVKISPQQRSAVVTIIPSVVSASQIVELVPDLSLDMGTQEKKSGACEEHSTPQAGEVMLKMKVEGMTCHSCTSTIEGKVGKLQGVQRIKVSLDNQEATIVFQPHLITAEEIKKQIEAVGFPAFI--KKQPKY 244

HSP 4 Score: 76.2554 bits (186), Expect = 2.322e-13
Identity = 48/162 (29.63%), Postives = 77/162 (47.53%), Query Frame = 1

Query:  319 IQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMAS----------------DIADTINDMGFDAEIFQFKEHTKDIIE--------VMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKL 732
            I+GM C SCV  IE+ +  L+ V S +++L +    V Y+  L+                    IA  +            ++   +I+         + I GMTC+SCV +IE  +++  G+ S+ V+L    G  +FDP + SP  + +AIE+MGFDA L
Sbjct:  283 IEGMHCKSCVSNIESALSTLQYVSSIVVSLENRSAIVKYNASLVTPEMLRKAIEAISPGQYRVSIASEVESTASSPSSSSLQKMPLNIVSQPLTQEAVININGMTCNSCVQSIEGVISKKPGVKSIHVSLANSTGTIEFDPLLTSPETLREAIEDMGFDAAL 444

HSP 5 Score: 75.0998 bits (183), Expect = 5.942e-13
Identity = 49/162 (30.25%), Postives = 78/162 (48.15%), Query Frame = 1

Query:  313 MRIQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMGFDAEIFQFKEHTK-DIIEV-----------------------------MIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIE 708
            M+++GMTC SC  TIE +V KL+GV+   ++L +    + + P LI A +I   I  +GF A I +  ++ K   I+V                              I+GM C SCV  IES L+ +Q + S+ V+L       K++  +++P  +  AIE
Sbjct:  175 MKVEGMTCHSCTSTIEGKVGKLQGVQRIKVSLDNQEATIVFQPHLITAEEIKKQIEAVGFPAFIKKQPKYLKLGAIDVERLKNTPVKSSEGSQQKSPSYPSDSTTMFTIEGMHCKSCVSNIESALSTLQYVSSIVVSLENRSAIVKYNASLVTPEMLRKAIE 336

HSP 6 Score: 69.3218 bits (168), Expect = 3.450e-11
Identity = 46/168 (27.38%), Postives = 80/168 (47.62%), Query Frame = 1

Query:  319 IQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMGFDAEIFQFKEHTKDIIEVMIQG--MTCSSCVYT----IESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKLAPKKTNKYNDH----VGESIKKWK 792
            ++GMTC SCV TIE Q+ K+ GV    ++L      + YDP L     + + I+DMGFDA +     H  + + V+     +T ++ +      I+S L + +G+  VK++           P ++S   I++ + ++  D     KK+    +H     GE + K K
Sbjct:   14 VEGMTCISCVRTIEQQIGKVNGVHHIKVSLEEKSATIIYDPKLQTPKTLQEAIDDMGFDALL-----HNANPLPVLTNTVFLTVTAPLTLPWDHIQSTLLKTKGVTGVKISPQQRSAVVTIIPSVVSASQIVELVPDLSLDMGTQEKKSGACEEHSTPQAGEVMLKMK 176

HSP 7 Score: 64.3142 bits (155), Expect = 1.079e-9
Identity = 26/66 (39.39%), Postives = 46/66 (69.70%), Query Frame = 1

Query:  535 IEVMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKL 732
            I + ++GMTC SCV TIE ++ ++ G+  +KV+L  +     +DP++ +P+ + +AI++MGFDA L
Sbjct:   10 ITITVEGMTCISCVRTIEQQIGKVNGVHHIKVSLEEKSATIIYDPKLQTPKTLQEAIDDMGFDALL 75

[Close]

BLAST of Copper-transporting ATPase 1 vs. Ensembl Mouse
Match: Atp7a (ATPase, Cu++ transporting, alpha polypeptide [Source:MGI Symbol;Acc:MGI:99400])

HSP 1 Score: 827.78 bits (2137), Expect = 0.000e+0
Identity = 467/973 (48.00%), Postives = 637/973 (65.47%), Query Frame = 1

Query:  226 TLCEAIENLGF----------------------LINKNKETDN--TKELFKCHMRIQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMGFDAEIFQFKEHTKDIIEVMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKLAPK-KTNKYNDHVGESIKKWKHSFLISLIFGVPTMIVMMVFMYGFSHRMQVIHLKNGINVTVMVSNAPIXXXXX------XXXXXXXXXXXXPVQFYGARYFYVQAYKSIKHGSANMDVLVVMATSVSYIYSFIVILVSMILRQDSSPQTFFETTPMLIVFLSLGRWLEHIAKGKTSEALSKLLSLQAFEATIIVNDNQ-----ERKISXXXXXXXXXXXXXPGEKIPIDGRVVSGKSRCDESLITGESMSVEKIPGSDVIGGTLNISGMLIIRATLVGEDSALNQIVKLVEEAQTSKAPIQELADKVAGLFVPGVIICSMFTLLIWIAIGYTN----PNLLPGHSSINTDNTELIWKYAFQLAITVLSVACPCSLGLATPTAVMVGTGVGAINGILIKGGVPLEKMHQLDVIVFDKTGTITTGKPSVTNFVMCVENVTSQI-RNCILLMLGAAESSSEHPIGKAILQYVRETCDINEMPQVVHSKSVSGFGLEC------SLKLQSDMFVPDSEIDNV-LVKINDFQENNLTENLKETSVKWRKINEPVEVVLYLGNRNMMKENHISIPDKLDELMSRDEDNGRTVVLMAIDKVLLAMISIADQVKKEAALVVYTLEKMGVEVFLLTGDNHKTATAIAKEIGIRNVFAEVLPSHKVAKIQQIQNMSKYKRSWLFSCCSKPSKLTNVAMVGDGINDSPALAQADVGIAIGTGTDVAVEAADVVLIRNSLLDVIAAMKLSKDTVRRIRQNFVAATMYNLIGIPIAAGALMPIGVVFMPWMA 3000
            TL EAIE++GF                      L+  + E +N  T    KC++++ GMTC+SCV  IE  + + +G+ S L+ L++   EV Y+P +I    IA+ I ++GF A + +       I+E++++GMTC+SCV+ IES L + +GI    VAL T K   K+DP+II PRDI+  I  +GF+A L  K ++  + DH  E IK+W+ SFL+SL F +P M  +MV+M    H +  +H    ++   M++    +F         S+ NLL  L   PVQF G  YFY+QAYK++KH +ANMDVL+V+AT++++ YS +++LV+M  R   +P TFF+T PML VF++LGRWLEHIAKGKTSEAL+KL+SLQA EATI+  +++     E ++ V+LV++GD++KV+PG K P+DGRV+ G S  DESLITGE+M V K PGS VI G++N +G L+IRAT VG D+ L+QIVKLVEEAQTSKAPIQ+ ADK++G FVP +++ S+ TLL+WI IG+ N        PG++  +   TE I ++AFQ +ITVL +ACPCSLGLATPTAVMVGTGVGA NGILIKGG PLE  H++ V+VFDKTGTIT G P V    + VE  +++I RN IL ++G AES+SEHP+G A+ +Y ++  D   +      + V G G+ C       L  +S++ + ++ I N  LV+I+   E + T +               +  + +GNR  M  N + I + +DE M   E  GRT VL+ ID  L  +I+IAD VK EA L V+ L+ MG+EV L+TGDN KTA +IA ++GI  VFAEVLPSHKVAK++Q+Q   K                  VAMVGDGINDSPALA A+VGIAIGTGTDVA+EAADVVLIRN LLDV+A++ LS+ TV+RIR NFV A +YNL+GIPIAAG  +PIG+V  PWM 
Sbjct:  430 TLREAIEDMGFDAALPDMKEPLVVIAQPSLETPLLPSSNELENVMTSVQNKCYIQVSGMTCASCVANIERNLRREEGIYSVLVALMAGKAEVRYNPAVIQPRVIAEFIRELGFGAMVMENAGEGNGILELVVRGMTCASCVHKIESTLTKHKGIFYCSVALATNKAHIKYDPEIIGPRDIIHTIGSLGFEASLVKKDRSANHLDHKRE-IKQWRGSFLVSLFFCIPVM-GLMVYMMVMDHHLATLHHNQNMSNEEMINMHSAMFLERQILPGLSIMNLLSLLLCLPVQFCGGWYFYIQAYKALKHKTANMDVLIVLATTIAFAYSLVILLVAMFERAKVNPITFFDTPPMLFVFIALGRWLEHIAKGKTSEALAKLISLQATEATIVTLNSENLLLSEEQVDVELVQRGDIIKVVPGGKFPVDGRVIEGHSMVDESLITGEAMPVAKKPGSTVIAGSINQNGSLLIRATHVGADTTLSQIVKLVEEAQTSKAPIQQFADKLSGYFVPFIVLVSIVTLLVWIIIGFQNFEIVETYFPGYNR-SISRTETIIRFAFQASITVLCIACPCSLGLATPTAVMVGTGVGAQNGILIKGGEPLEMAHKVKVVVFDKTGTITHGTPVVNQVKVLVE--SNKISRNKILAIVGTAESNSEHPLGAAVTKYCKKELDTETLGTCTDFQVVPGCGISCKVTNIEGLLHKSNLKIEENNIKNASLVQIDAINEQSSTSSSMIIDAHLSNAVNTQQYKVLIGNREWMIRNGLVISNDVDESMIEHERRGRTAVLVTIDDELCGLIAIADTVKPEAELAVHILKSMGLEVVLMTGDNSKTARSIASQVGITKVFAEVLPSHKVAKVKQLQEEGK-----------------RVAMVGDGINDSPALAMANVGIAIGTGTDVAIEAADVVLIRNDLLDVVASIDLSRKTVKRIRINFVFALIYNLVGIPIAAGVFLPIGLVLQPWMG 1380

HSP 2 Score: 103.605 bits (257), Expect = 1.111e-21
Identity = 59/164 (35.98%), Postives = 86/164 (52.44%), Query Frame = 1

Query:  313 MRIQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMGFDAEIFQFKE----------------HTKDIIEVM----------IQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDA 726
            + I GMTC+SCV +IE  + K  GVKS  ++L ++ G + +DP L     + + I DMGFDA +   KE                 + ++  VM          + GMTC+SCV  IE  L + +GI SV VAL   K + +++P +I PR I + I E+GF A
Sbjct:  381 ININGMTCNSCVQSIEGVISKKPGVKSIHVSLANSTGTIEFDPLLTSPETLREAIEDMGFDAALPDMKEPLVVIAQPSLETPLLPSSNELENVMTSVQNKCYIQVSGMTCASCVANIERNLRREEGIYSVLVALMAGKAEVRYNPAVIQPRVIAEFIRELGFGA 544

HSP 3 Score: 77.411 bits (189), Expect = 1.160e-13
Identity = 63/190 (33.16%), Postives = 94/190 (49.47%), Query Frame = 1

Query:  226 TLCEAIENLGF---LINKNKETDNTKELFKCHMRIQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMGFDAEIFQFK-----EH-TKDIIEVM----IQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKLAPKKTNKY 756
            TL EAI+++GF   L N N     T  +F   + +         H I++ +LK KGV    I+       VT  P ++ AS I + + D+  D    + K     EH T    EVM    ++GMTC SC  TIE K+ ++QG+  +KV+L  ++    F P +I+  +I   IE +GF A +  KK  KY
Sbjct:   61 TLQEAIDDMGFDALLHNANPLPVLTNTVF---LTVTAPLTLPWDH-IQSTLLKTKGVTGVKISPQQRSAVVTIIPSVVSASQIVELVPDLSLDMGTQEKKSGACEEHSTPQAGEVMLKMKVEGMTCHSCTSTIEGKVGKLQGVQRIKVSLDNQEATIVFQPHLITAEEIKKQIEAVGFPAFI--KKQPKY 244

HSP 4 Score: 76.2554 bits (186), Expect = 2.264e-13
Identity = 49/166 (29.52%), Postives = 78/166 (46.99%), Query Frame = 1

Query:  319 IQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMAS----------------DIADTINDMGFDAEIFQFKEHTKDIIE--------VMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKLAPKK 744
            I+GM C SCV  IE+ +  L+ V S +++L +    V Y+  L+                    IA  +            ++   +I+         + I GMTC+SCV +IE  +++  G+ S+ V+L    G  +FDP + SP  + +AIE+MGFDA L   K
Sbjct:  283 IEGMHCKSCVSNIESALSTLQYVSSIVVSLENRSAIVKYNASLVTPEMLRKAIEAISPGQYRVSIASEVESTASSPSSSSLQKMPLNIVSQPLTQEAVININGMTCNSCVQSIEGVISKKPGVKSIHVSLANSTGTIEFDPLLTSPETLREAIEDMGFDAALPDMK 448

HSP 5 Score: 74.7146 bits (182), Expect = 6.094e-13
Identity = 49/162 (30.25%), Postives = 78/162 (48.15%), Query Frame = 1

Query:  313 MRIQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMGFDAEIFQFKEHTK-DIIEV-----------------------------MIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIE 708
            M+++GMTC SC  TIE +V KL+GV+   ++L +    + + P LI A +I   I  +GF A I +  ++ K   I+V                              I+GM C SCV  IES L+ +Q + S+ V+L       K++  +++P  +  AIE
Sbjct:  175 MKVEGMTCHSCTSTIEGKVGKLQGVQRIKVSLDNQEATIVFQPHLITAEEIKKQIEAVGFPAFIKKQPKYLKLGAIDVERLKNTPVKSSEGSQQKSPSYPSDSTTMFTIEGMHCKSCVSNIESALSTLQYVSSIVVSLENRSAIVKYNASLVTPEMLRKAIE 336

HSP 6 Score: 68.9366 bits (167), Expect = 3.508e-11
Identity = 46/168 (27.38%), Postives = 80/168 (47.62%), Query Frame = 1

Query:  319 IQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMGFDAEIFQFKEHTKDIIEVMIQG--MTCSSCVYT----IESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKLAPKKTNKYNDH----VGESIKKWK 792
            ++GMTC SCV TIE Q+ K+ GV    ++L      + YDP L     + + I+DMGFDA +     H  + + V+     +T ++ +      I+S L + +G+  VK++           P ++S   I++ + ++  D     KK+    +H     GE + K K
Sbjct:   14 VEGMTCISCVRTIEQQIGKVNGVHHIKVSLEEKSATIIYDPKLQTPKTLQEAIDDMGFDALL-----HNANPLPVLTNTVFLTVTAPLTLPWDHIQSTLLKTKGVTGVKISPQQRSAVVTIIPSVVSASQIVELVPDLSLDMGTQEKKSGACEEHSTPQAGEVMLKMK 176

HSP 7 Score: 64.3142 bits (155), Expect = 1.106e-9
Identity = 26/66 (39.39%), Postives = 46/66 (69.70%), Query Frame = 1

Query:  535 IEVMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKL 732
            I + ++GMTC SCV TIE ++ ++ G+  +KV+L  +     +DP++ +P+ + +AI++MGFDA L
Sbjct:   10 ITITVEGMTCISCVRTIEQQIGKVNGVHHIKVSLEEKSATIIYDPKLQTPKTLQEAIDDMGFDALL 75

[Close]

BLAST of Copper-transporting ATPase 1 vs. Ensembl Mouse
Match: Atp7b (ATPase, Cu++ transporting, beta polypeptide [Source:MGI Symbol;Acc:MGI:103297])

HSP 1 Score: 827.78 bits (2137), Expect = 0.000e+0
Identity = 445/908 (49.01%), Postives = 607/908 (66.85%), Query Frame = 1

Query:  304 KCHMRIQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMGFDAEIFQFKEHTKDIIEVMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKLAPKKTNKYN-DHVGESIKKWKHSFLISLIFGVPTMIVMMVFMYGFSHRMQVIHLKNGINVTVMVSNAPIXXXXXXXXXXXXXXXXXPVQFYGARYFYVQAYKSIKHGSANMDVLVVMATSVSYIYSFIVILVSMILRQDSSPQTFFETTPMLIVFLSLGRWLEHIAKGKTSEALSKLLSLQAFEATIIV--NDN---QERKISXXXXXXXXXXXXXPGEKIPIDGRVVSGKSRCDESLITGESMSVEKIPGSDVIGGTLNISGMLIIRATLVGEDSALNQIVKLVEEAQTSKAPIQELADKVAGLFVPGVIICSMFTLLIWIAIGYTNPNLLPGH---SSINTDNTELIWKYAFQLAITVLSVACPCSLGLATPTAVMVGTGVGAINGILIKGGVPLEKMHQLDVIVFDKTGTITTGKPSVTNFVMCVENVTSQIRNCILLMLGAAESSSEHPIGKAILQYVRETCDINEMPQVVHSKSVSGFGLECSLKLQSDMFVPDSEIDNVLVKINDFQENNLTENLKETSVKWRKINEPVEVVLYLGNRNMMKENHISIPDKLDELMSRDEDNGRTVVLMAIDKVLLAMISIADQVKKEAALVVYTLEKMGVEVFLLTGDNHKTATAIAKEIGIRNVFAEVLPSHKVAKIQQIQNMSKYKRSWLFSCCSKPSKLTNVAMVGDGINDSPALAQADVGIAIGTGTDVAVEAADVVLIRNSLLDVIAAMKLSKDTVRRIRQNFVAATMYNLIGIPIAAGALMPIGVVFMPWMA 3000
            KC ++I+GMTC+SCV  IE  + +  G+ S L+ L+S   EV YDP++I +  IA  I D+GF+A + +    ++  IE++I GMTC+SCV+ IESKL +  GI    VAL T K   KFDP+I+ PRDI+  IEE+GF A LA +  N ++ DH  E IK+WK SFL SL+FG+P M +M+  +   S   + + L + I   + V N                     VQF G  YFYVQAYKS++H SANMDVL+V+AT+++Y YS ++++V++  + + SP TFF+T PML VF++LGRWLEH+AK KTSEAL+KL+SLQA EAT++    DN   +E ++ ++LV++GD++KV+PG K P+DG+V+ G +  DESLITGE+M V K PGS VI G++N  G ++++AT VG D+ L QIVKLVEEAQ SKAPIQ+LAD+ +G FVP +II S  TL++WI IG+ +  ++  +    S +   TE+I ++AFQ +ITVL +ACPCSLGLATPTAVMVGTGV A NG+LIKGG PLE  H++  ++FDKTGTIT G P V  F++  +  T  +R  +L ++G AE+SSEHP+G A+ +Y +E      +      ++V G G+ C +          S ++ +L + +D   + +      T     +   P    + +GNR  M+ N ++I   + + M+  E  G+T +L+AID VL  MI+IAD VK EAAL +YTL+ MGV+V L+TGDN KTA AIA ++GI  VFAEVLPSHKVAK+Q++QN  K                  VAMVGDG+NDSPALAQADVGIAIGTGTDVA+EAADVVLIRN LLDV+A++ LSK TVRRIR N V A +YN++GIPIAAG  MPIG+V  PWM 
Sbjct:  491 KCFVQIKGMTCASCVSNIERSLQRHAGILSVLVALMSGKAEVKYDPEIIQSPRIAQLIQDLGFEASVMEDNTVSEGDIELIITGMTCASCVHNIESKLTRTNGITYASVALATSKAHVKFDPEIVGPRDIIKIIEEIGFHASLAQRNPNAHHLDHKTE-IKQWKKSFLCSLVFGIPVMGLMVYMLIPSSTPQETMVLDHNIIPGLSVLNLIFFILCTF------------VQFLGGWYFYVQAYKSLRHRSANMDVLIVLATTIAYAYSLVILVVAVAEKAEKSPVTFFDTPPMLFVFIALGRWLEHVAKSKTSEALAKLMSLQATEATVVTLGEDNLILREEQVPMELVQRGDVIKVVPGGKFPVDGKVLEGNTMADESLITGEAMPVTKKPGSIVIAGSINAHGSVLLKATHVGNDTTLAQIVKLVEEAQMSKAPIQQLADRFSGYFVPFIIIISTLTLVVWIVIGFVDFGVVQKYFPSPSKHISQTEVIIRFAFQTSITVLCIACPCSLGLATPTAVMVGTGVAAQNGVLIKGGKPLEMAHKIKTVMFDKTGTITHGVPRVMRFLLLADVATLPLRK-VLAVVGTAEASSEHPLGVAVTKYCKEELGTETLGYSTDFQAVPGCGISCKV----------SNVEGILAR-SDLTAHPVGVGNPPTG----EGAGPQTFSVLIGNREWMRRNGLTISSDISDAMTDHEMKGQTAILVAIDGVLCGMIAIADAVKPEAALAIYTLKSMGVDVALITGDNRKTARAIATQVGINKVFAEVLPSHKVAKVQELQNEGK-----------------KVAMVGDGVNDSPALAQADVGIAIGTGTDVAIEAADVVLIRNDLLDVVASIHLSKRTVRRIRVNLVLALIYNMVGIPIAAGVFMPIGIVLQPWMG 1352

HSP 2 Score: 102.064 bits (253), Expect = 2.898e-21
Identity = 54/163 (33.13%), Postives = 91/163 (55.83%), Query Frame = 1

Query:  319 IQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMGFDAEIFQFKEHT---------KDIIEVMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDA---------KLAPKKTNK 753
            I GMTC SCV +IE+++  LKG+ +  ++L      V Y P ++    I   I DMGF+A   + K  +         + ++++ ++GMTC SCV +IE K+ ++QG++ +KV+L+ ++    + P +I P D+ D I +MGF+A         +L P   NK
Sbjct:   74 ILGMTCHSCVKSIEDRISSLKGIVNIKVSLEQGSATVRYVPSVMNLQQICLQIEDMGFEASAAEGKAASWPSRSSPAQEAVVKLRVEGMTCQSCVSSIEGKIRKLQGVVRIKVSLSNQEAVITYQPYLIQPEDLRDHICDMGFEAAIKNRTAPLRLGPIDVNK 236

HSP 3 Score: 63.5438 bits (153), Expect = 1.861e-9
Identity = 57/203 (28.08%), Postives = 83/203 (40.89%), Query Frame = 1

Query:  313 MRIQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMGFD----AEIF------QFKE-----HTKDIIEVMIQGM------------------TCSSCVYTIESK--------------------LAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKLAPKKTNKYND 762
            + I G+TC+S V  IE+ + + KGV+   I+L    G V YDP ++   ++   + DMGF+    +E F       FK       T   I   +Q M                  T SS   T   K                    L +  GILSV VAL + K + K+DP+II    I   I+++GF+A +    T    D
Sbjct:  365 LTISGITCASSVQPIEDMLSQRKGVQQTSISLAEGTGAVLYDPSIVSLDELRTAVEDMGFEVSVNSETFTINPVRNFKSGNSVPQTMGDIAGSVQKMAPDTRGLPTHQGPGHSSETPSSPGATASQKCFVQIKGMTCASCVSNIERSLQRHAGILSVLVALMSGKAEVKYDPEIIQSPRIAQLIQDLGFEASVMEDNTVSEGD 567

HSP 4 Score: 62.003 bits (149), Expect = 4.923e-9
Identity = 31/94 (32.98%), Postives = 53/94 (56.38%), Query Frame = 1

Query:  229 LCEAIENLGFLINKNKETDNTKELFKCHMRIQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMGFDAEIFQ 510
            + + I++LGF    +   DNT       + I GMTC+SCVH IE+++ +  G+  A + L ++   V +DP+++   DI   I ++GF A + Q
Sbjct:  544 IAQLIQDLGF--EASVMEDNTVSEGDIELIITGMTCASCVHNIESKLTRTNGITYASVALATSKAHVKFDPEIVGPRDIIKIIEEIGFHASLAQ 635

HSP 5 Score: 56.225 bits (134), Expect = 3.129e-7
Identity = 26/72 (36.11%), Postives = 45/72 (62.50%), Query Frame = 1

Query:  541 VMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKLAPKKTNKY 756
            V I GMTC SCV +IE +++ ++GI+++KV+L       ++ P +++ + I   IE+MGF+A  A  K   +
Sbjct:   72 VNILGMTCHSCVKSIEDRISSLKGIVNIKVSLEQGSATVRYVPSVMNLQQICLQIEDMGFEASAAEGKAASW 143

[Close]

BLAST of Copper-transporting ATPase 1 vs. Ensembl Mouse
Match: Atp2a1 (ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 [Source:MGI Symbol;Acc:MGI:105058])

HSP 1 Score: 81.6481 bits (200), Expect = 4.156e-15
Identity = 53/193 (27.46%), Postives = 97/193 (50.26%), Query Frame = 1

Query: 2368 PDKLDELMSRDEDNGRTVVLMAIDKVLLAMISIADQVKKEAALVVYTLEKMGVEVFLLTGDNHKTATAIAKEIGIRNVFAEVLPSHKVAKIQQIQNMSKYKRSWLFSCC------SKPSKLTN--------VAMVGDGINDSPALAQADVGIAIGTGTDVAVEAADVVLIRNSLLDVIAAMKLSKDTVRRIRQ 2904
            P K +E++    D+    +   +D   + ++ + D  +KE    +      G+ V ++TGDN  TA AI + IGI +   EV       +      +++ + +   +CC      S  SK+           AM GDG+ND+PAL +A++GIA+G+GT VA  A+++VL  ++   ++AA++  +     ++Q
Sbjct:  570 PPKREEMVL---DDSAKFMEYEMDLTFVGVVGMLDPPRKEVTGSIQLCRDAGIRVIMITGDNKGTAIAICRRIGIFSENEEVTDRAYTGREFDDLPLAEQREACRRACCFARVEPSHKSKIVEYLQSYDEITAMTGDGVNDAPALKKAEIGIAMGSGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQ 759

[Close]

BLAST of Copper-transporting ATPase 1 vs. UniProt/SwissProt
Match: sp|Q64446|ATP7B_MOUSE (Copper-transporting ATPase 2 OS=Mus musculus OX=10090 GN=Atp7b PE=1 SV=2)

HSP 1 Score: 827.78 bits (2137), Expect = 0.000e+0
Identity = 445/908 (49.01%), Postives = 607/908 (66.85%), Query Frame = 1

Query:  304 KCHMRIQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMGFDAEIFQFKEHTKDIIEVMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKLAPKKTNKYN-DHVGESIKKWKHSFLISLIFGVPTMIVMMVFMYGFSHRMQVIHLKNGINVTVMVSNAPIXXXXXXXXXXXXXXXXXPVQFYGARYFYVQAYKSIKHGSANMDVLVVMATSVSYIYSFIVILVSMILRQDSSPQTFFETTPMLIVFLSLGRWLEHIAKGKTSEALSKLLSLQAFEATIIV--NDN---QERKISXXXXXXXXXXXXXPGEKIPIDGRVVSGKSRCDESLITGESMSVEKIPGSDVIGGTLNISGMLIIRATLVGEDSALNQIVKLVEEAQTSKAPIQELADKVAGLFVPGVIICSMFTLLIWIAIGYTNPNLLPGH---SSINTDNTELIWKYAFQLAITVLSVACPCSLGLATPTAVMVGTGVGAINGILIKGGVPLEKMHQLDVIVFDKTGTITTGKPSVTNFVMCVENVTSQIRNCILLMLGAAESSSEHPIGKAILQYVRETCDINEMPQVVHSKSVSGFGLECSLKLQSDMFVPDSEIDNVLVKINDFQENNLTENLKETSVKWRKINEPVEVVLYLGNRNMMKENHISIPDKLDELMSRDEDNGRTVVLMAIDKVLLAMISIADQVKKEAALVVYTLEKMGVEVFLLTGDNHKTATAIAKEIGIRNVFAEVLPSHKVAKIQQIQNMSKYKRSWLFSCCSKPSKLTNVAMVGDGINDSPALAQADVGIAIGTGTDVAVEAADVVLIRNSLLDVIAAMKLSKDTVRRIRQNFVAATMYNLIGIPIAAGALMPIGVVFMPWMA 3000
            KC ++I+GMTC+SCV  IE  + +  G+ S L+ L+S   EV YDP++I +  IA  I D+GF+A + +    ++  IE++I GMTC+SCV+ IESKL +  GI    VAL T K   KFDP+I+ PRDI+  IEE+GF A LA +  N ++ DH  E IK+WK SFL SL+FG+P M +M+  +   S   + + L + I   + V N                     VQF G  YFYVQAYKS++H SANMDVL+V+AT+++Y YS ++++V++  + + SP TFF+T PML VF++LGRWLEH+AK KTSEAL+KL+SLQA EAT++    DN   +E ++ ++LV++GD++KV+PG K P+DG+V+ G +  DESLITGE+M V K PGS VI G++N  G ++++AT VG D+ L QIVKLVEEAQ SKAPIQ+LAD+ +G FVP +II S  TL++WI IG+ +  ++  +    S +   TE+I ++AFQ +ITVL +ACPCSLGLATPTAVMVGTGV A NG+LIKGG PLE  H++  ++FDKTGTIT G P V  F++  +  T  +R  +L ++G AE+SSEHP+G A+ +Y +E      +      ++V G G+ C +          S ++ +L + +D   + +      T     +   P    + +GNR  M+ N ++I   + + M+  E  G+T +L+AID VL  MI+IAD VK EAAL +YTL+ MGV+V L+TGDN KTA AIA ++GI  VFAEVLPSHKVAK+Q++QN  K                  VAMVGDG+NDSPALAQADVGIAIGTGTDVA+EAADVVLIRN LLDV+A++ LSK TVRRIR N V A +YN++GIPIAAG  MPIG+V  PWM 
Sbjct:  491 KCFVQIKGMTCASCVSNIERSLQRHAGILSVLVALMSGKAEVKYDPEIIQSPRIAQLIQDLGFEASVMEDNTVSEGDIELIITGMTCASCVHNIESKLTRTNGITYASVALATSKAHVKFDPEIVGPRDIIKIIEEIGFHASLAQRNPNAHHLDHKTE-IKQWKKSFLCSLVFGIPVMGLMVYMLIPSSTPQETMVLDHNIIPGLSVLNLIFFILCTF------------VQFLGGWYFYVQAYKSLRHRSANMDVLIVLATTIAYAYSLVILVVAVAEKAEKSPVTFFDTPPMLFVFIALGRWLEHVAKSKTSEALAKLMSLQATEATVVTLGEDNLILREEQVPMELVQRGDVIKVVPGGKFPVDGKVLEGNTMADESLITGEAMPVTKKPGSIVIAGSINAHGSVLLKATHVGNDTTLAQIVKLVEEAQMSKAPIQQLADRFSGYFVPFIIIISTLTLVVWIVIGFVDFGVVQKYFPSPSKHISQTEVIIRFAFQTSITVLCIACPCSLGLATPTAVMVGTGVAAQNGVLIKGGKPLEMAHKIKTVMFDKTGTITHGVPRVMRFLLLADVATLPLRK-VLAVVGTAEASSEHPLGVAVTKYCKEELGTETLGYSTDFQAVPGCGISCKV----------SNVEGILAR-SDLTAHPVGVGNPPTG----EGAGPQTFSVLIGNREWMRRNGLTISSDISDAMTDHEMKGQTAILVAIDGVLCGMIAIADAVKPEAALAIYTLKSMGVDVALITGDNRKTARAIATQVGINKVFAEVLPSHKVAKVQELQNEGK-----------------KVAMVGDGVNDSPALAQADVGIAIGTGTDVAIEAADVVLIRNDLLDVVASIHLSKRTVRRIRVNLVLALIYNMVGIPIAAGVFMPIGIVLQPWMG 1352

HSP 2 Score: 102.064 bits (253), Expect = 2.027e-20
Identity = 54/163 (33.13%), Postives = 91/163 (55.83%), Query Frame = 1

Query:  319 IQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMGFDAEIFQFKEHT---------KDIIEVMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDA---------KLAPKKTNK 753
            I GMTC SCV +IE+++  LKG+ +  ++L      V Y P ++    I   I DMGF+A   + K  +         + ++++ ++GMTC SCV +IE K+ ++QG++ +KV+L+ ++    + P +I P D+ D I +MGF+A         +L P   NK
Sbjct:   74 ILGMTCHSCVKSIEDRISSLKGIVNIKVSLEQGSATVRYVPSVMNLQQICLQIEDMGFEASAAEGKAASWPSRSSPAQEAVVKLRVEGMTCQSCVSSIEGKIRKLQGVVRIKVSLSNQEAVITYQPYLIQPEDLRDHICDMGFEAAIKNRTAPLRLGPIDVNK 236

HSP 3 Score: 63.5438 bits (153), Expect = 1.302e-8
Identity = 57/203 (28.08%), Postives = 83/203 (40.89%), Query Frame = 1

Query:  313 MRIQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMGFD----AEIF------QFKE-----HTKDIIEVMIQGM------------------TCSSCVYTIESK--------------------LAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKLAPKKTNKYND 762
            + I G+TC+S V  IE+ + + KGV+   I+L    G V YDP ++   ++   + DMGF+    +E F       FK       T   I   +Q M                  T SS   T   K                    L +  GILSV VAL + K + K+DP+II    I   I+++GF+A +    T    D
Sbjct:  365 LTISGITCASSVQPIEDMLSQRKGVQQTSISLAEGTGAVLYDPSIVSLDELRTAVEDMGFEVSVNSETFTINPVRNFKSGNSVPQTMGDIAGSVQKMAPDTRGLPTHQGPGHSSETPSSPGATASQKCFVQIKGMTCASCVSNIERSLQRHAGILSVLVALMSGKAEVKYDPEIIQSPRIAQLIQDLGFEASVMEDNTVSEGD 567

HSP 4 Score: 62.003 bits (149), Expect = 3.444e-8
Identity = 31/94 (32.98%), Postives = 53/94 (56.38%), Query Frame = 1

Query:  229 LCEAIENLGFLINKNKETDNTKELFKCHMRIQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMGFDAEIFQ 510
            + + I++LGF    +   DNT       + I GMTC+SCVH IE+++ +  G+  A + L ++   V +DP+++   DI   I ++GF A + Q
Sbjct:  544 IAQLIQDLGF--EASVMEDNTVSEGDIELIITGMTCASCVHNIESKLTRTNGITYASVALATSKAHVKFDPEIVGPRDIIKIIEEIGFHASLAQ 635

HSP 5 Score: 56.225 bits (134), Expect = 2.188e-6
Identity = 26/72 (36.11%), Postives = 45/72 (62.50%), Query Frame = 1

Query:  541 VMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKLAPKKTNKY 756
            V I GMTC SCV +IE +++ ++GI+++KV+L       ++ P +++ + I   IE+MGF+A  A  K   +
Sbjct:   72 VNILGMTCHSCVKSIEDRISSLKGIVNIKVSLEQGSATVRYVPSVMNLQQICLQIEDMGFEASAAEGKAASW 143

[Close]

BLAST of Copper-transporting ATPase 1 vs. UniProt/SwissProt
Match: sp|Q64430|ATP7A_MOUSE (Copper-transporting ATPase 1 OS=Mus musculus OX=10090 GN=Atp7a PE=1 SV=3)

HSP 1 Score: 827.78 bits (2137), Expect = 0.000e+0
Identity = 467/973 (48.00%), Postives = 637/973 (65.47%), Query Frame = 1

Query:  226 TLCEAIENLGF----------------------LINKNKETDN--TKELFKCHMRIQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMGFDAEIFQFKEHTKDIIEVMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKLAPK-KTNKYNDHVGESIKKWKHSFLISLIFGVPTMIVMMVFMYGFSHRMQVIHLKNGINVTVMVSNAPIXXXXX------XXXXXXXXXXXXPVQFYGARYFYVQAYKSIKHGSANMDVLVVMATSVSYIYSFIVILVSMILRQDSSPQTFFETTPMLIVFLSLGRWLEHIAKGKTSEALSKLLSLQAFEATIIVNDNQ-----ERKISXXXXXXXXXXXXXPGEKIPIDGRVVSGKSRCDESLITGESMSVEKIPGSDVIGGTLNISGMLIIRATLVGEDSALNQIVKLVEEAQTSKAPIQELADKVAGLFVPGVIICSMFTLLIWIAIGYTN----PNLLPGHSSINTDNTELIWKYAFQLAITVLSVACPCSLGLATPTAVMVGTGVGAINGILIKGGVPLEKMHQLDVIVFDKTGTITTGKPSVTNFVMCVENVTSQI-RNCILLMLGAAESSSEHPIGKAILQYVRETCDINEMPQVVHSKSVSGFGLEC------SLKLQSDMFVPDSEIDNV-LVKINDFQENNLTENLKETSVKWRKINEPVEVVLYLGNRNMMKENHISIPDKLDELMSRDEDNGRTVVLMAIDKVLLAMISIADQVKKEAALVVYTLEKMGVEVFLLTGDNHKTATAIAKEIGIRNVFAEVLPSHKVAKIQQIQNMSKYKRSWLFSCCSKPSKLTNVAMVGDGINDSPALAQADVGIAIGTGTDVAVEAADVVLIRNSLLDVIAAMKLSKDTVRRIRQNFVAATMYNLIGIPIAAGALMPIGVVFMPWMA 3000
            TL EAIE++GF                      L+  + E +N  T    KC++++ GMTC+SCV  IE  + + +G+ S L+ L++   EV Y+P +I    IA+ I ++GF A + +       I+E++++GMTC+SCV+ IES L + +GI    VAL T K   K+DP+II PRDI+  I  +GF+A L  K ++  + DH  E IK+W+ SFL+SL F +P M  +MV+M    H +  +H    ++   M++    +F         S+ NLL  L   PVQF G  YFY+QAYK++KH +ANMDVL+V+AT++++ YS +++LV+M  R   +P TFF+T PML VF++LGRWLEHIAKGKTSEAL+KL+SLQA EATI+  +++     E ++ V+LV++GD++KV+PG K P+DGRV+ G S  DESLITGE+M V K PGS VI G++N +G L+IRAT VG D+ L+QIVKLVEEAQTSKAPIQ+ ADK++G FVP +++ S+ TLL+WI IG+ N        PG++  +   TE I ++AFQ +ITVL +ACPCSLGLATPTAVMVGTGVGA NGILIKGG PLE  H++ V+VFDKTGTIT G P V    + VE  +++I RN IL ++G AES+SEHP+G A+ +Y ++  D   +      + V G G+ C       L  +S++ + ++ I N  LV+I+   E + T +               +  + +GNR  M  N + I + +DE M   E  GRT VL+ ID  L  +I+IAD VK EA L V+ L+ MG+EV L+TGDN KTA +IA ++GI  VFAEVLPSHKVAK++Q+Q   K                  VAMVGDGINDSPALA A+VGIAIGTGTDVA+EAADVVLIRN LLDV+A++ LS+ TV+RIR NFV A +YNL+GIPIAAG  +PIG+V  PWM 
Sbjct:  430 TLREAIEDMGFDAALPDMKEPLVVIAQPSLETPLLPSSNELENVMTSVQNKCYIQVSGMTCASCVANIERNLRREEGIYSVLVALMAGKAEVRYNPAVIQPRVIAEFIRELGFGAMVMENAGEGNGILELVVRGMTCASCVHKIESTLTKHKGIFYCSVALATNKAHIKYDPEIIGPRDIIHTIGSLGFEASLVKKDRSANHLDHKRE-IKQWRGSFLVSLFFCIPVM-GLMVYMMVMDHHLATLHHNQNMSNEEMINMHSAMFLERQILPGLSIMNLLSLLLCLPVQFCGGWYFYIQAYKALKHKTANMDVLIVLATTIAFAYSLVILLVAMFERAKVNPITFFDTPPMLFVFIALGRWLEHIAKGKTSEALAKLISLQATEATIVTLNSENLLLSEEQVDVELVQRGDIIKVVPGGKFPVDGRVIEGHSMVDESLITGEAMPVAKKPGSTVIAGSINQNGSLLIRATHVGADTTLSQIVKLVEEAQTSKAPIQQFADKLSGYFVPFIVLVSIVTLLVWIIIGFQNFEIVETYFPGYNR-SISRTETIIRFAFQASITVLCIACPCSLGLATPTAVMVGTGVGAQNGILIKGGEPLEMAHKVKVVVFDKTGTITHGTPVVNQVKVLVE--SNKISRNKILAIVGTAESNSEHPLGAAVTKYCKKELDTETLGTCTDFQVVPGCGISCKVTNIEGLLHKSNLKIEENNIKNASLVQIDAINEQSSTSSSMIIDAHLSNAVNTQQYKVLIGNREWMIRNGLVISNDVDESMIEHERRGRTAVLVTIDDELCGLIAIADTVKPEAELAVHILKSMGLEVVLMTGDNSKTARSIASQVGITKVFAEVLPSHKVAKVKQLQEEGK-----------------RVAMVGDGINDSPALAMANVGIAIGTGTDVAIEAADVVLIRNDLLDVVASIDLSRKTVKRIRINFVFALIYNLVGIPIAAGVFLPIGLVLQPWMG 1380

HSP 2 Score: 103.605 bits (257), Expect = 7.772e-21
Identity = 59/164 (35.98%), Postives = 86/164 (52.44%), Query Frame = 1

Query:  313 MRIQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMGFDAEIFQFKE----------------HTKDIIEVM----------IQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDA 726
            + I GMTC+SCV +IE  + K  GVKS  ++L ++ G + +DP L     + + I DMGFDA +   KE                 + ++  VM          + GMTC+SCV  IE  L + +GI SV VAL   K + +++P +I PR I + I E+GF A
Sbjct:  381 ININGMTCNSCVQSIEGVISKKPGVKSIHVSLANSTGTIEFDPLLTSPETLREAIEDMGFDAALPDMKEPLVVIAQPSLETPLLPSSNELENVMTSVQNKCYIQVSGMTCASCVANIERNLRREEGIYSVLVALMAGKAEVRYNPAVIQPRVIAEFIRELGFGA 544

HSP 3 Score: 77.411 bits (189), Expect = 8.113e-13
Identity = 63/190 (33.16%), Postives = 94/190 (49.47%), Query Frame = 1

Query:  226 TLCEAIENLGF---LINKNKETDNTKELFKCHMRIQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMGFDAEIFQFK-----EH-TKDIIEVM----IQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKLAPKKTNKY 756
            TL EAI+++GF   L N N     T  +F   + +         H I++ +LK KGV    I+       VT  P ++ AS I + + D+  D    + K     EH T    EVM    ++GMTC SC  TIE K+ ++QG+  +KV+L  ++    F P +I+  +I   IE +GF A +  KK  KY
Sbjct:   61 TLQEAIDDMGFDALLHNANPLPVLTNTVF---LTVTAPLTLPWDH-IQSTLLKTKGVTGVKISPQQRSAVVTIIPSVVSASQIVELVPDLSLDMGTQEKKSGACEEHSTPQAGEVMLKMKVEGMTCHSCTSTIEGKVGKLQGVQRIKVSLDNQEATIVFQPHLITAEEIKKQIEAVGFPAFI--KKQPKY 244

HSP 4 Score: 76.2554 bits (186), Expect = 1.583e-12
Identity = 49/166 (29.52%), Postives = 78/166 (46.99%), Query Frame = 1

Query:  319 IQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMAS----------------DIADTINDMGFDAEIFQFKEHTKDIIE--------VMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKLAPKK 744
            I+GM C SCV  IE+ +  L+ V S +++L +    V Y+  L+                    IA  +            ++   +I+         + I GMTC+SCV +IE  +++  G+ S+ V+L    G  +FDP + SP  + +AIE+MGFDA L   K
Sbjct:  283 IEGMHCKSCVSNIESALSTLQYVSSIVVSLENRSAIVKYNASLVTPEMLRKAIEAISPGQYRVSIASEVESTASSPSSSSLQKMPLNIVSQPLTQEAVININGMTCNSCVQSIEGVISKKPGVKSIHVSLANSTGTIEFDPLLTSPETLREAIEDMGFDAALPDMK 448

HSP 5 Score: 74.7146 bits (182), Expect = 4.262e-12
Identity = 49/162 (30.25%), Postives = 78/162 (48.15%), Query Frame = 1

Query:  313 MRIQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMGFDAEIFQFKEHTK-DIIEV-----------------------------MIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIE 708
            M+++GMTC SC  TIE +V KL+GV+   ++L +    + + P LI A +I   I  +GF A I +  ++ K   I+V                              I+GM C SCV  IES L+ +Q + S+ V+L       K++  +++P  +  AIE
Sbjct:  175 MKVEGMTCHSCTSTIEGKVGKLQGVQRIKVSLDNQEATIVFQPHLITAEEIKKQIEAVGFPAFIKKQPKYLKLGAIDVERLKNTPVKSSEGSQQKSPSYPSDSTTMFTIEGMHCKSCVSNIESALSTLQYVSSIVVSLENRSAIVKYNASLVTPEMLRKAIE 336

HSP 6 Score: 68.9366 bits (167), Expect = 2.454e-10
Identity = 46/168 (27.38%), Postives = 80/168 (47.62%), Query Frame = 1

Query:  319 IQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMGFDAEIFQFKEHTKDIIEVMIQG--MTCSSCVYT----IESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKLAPKKTNKYNDH----VGESIKKWK 792
            ++GMTC SCV TIE Q+ K+ GV    ++L      + YDP L     + + I+DMGFDA +     H  + + V+     +T ++ +      I+S L + +G+  VK++           P ++S   I++ + ++  D     KK+    +H     GE + K K
Sbjct:   14 VEGMTCISCVRTIEQQIGKVNGVHHIKVSLEEKSATIIYDPKLQTPKTLQEAIDDMGFDALL-----HNANPLPVLTNTVFLTVTAPLTLPWDHIQSTLLKTKGVTGVKISPQQRSAVVTIIPSVVSASQIVELVPDLSLDMGTQEKKSGACEEHSTPQAGEVMLKMK 176

HSP 7 Score: 64.3142 bits (155), Expect = 7.739e-9
Identity = 26/66 (39.39%), Postives = 46/66 (69.70%), Query Frame = 1

Query:  535 IEVMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKL 732
            I + ++GMTC SCV TIE ++ ++ G+  +KV+L  +     +DP++ +P+ + +AI++MGFDA L
Sbjct:   10 ITITVEGMTCISCVRTIEQQIGKVNGVHHIKVSLEEKSATIIYDPKLQTPKTLQEAIDDMGFDALL 75

[Close]

BLAST of Copper-transporting ATPase 1 vs. UniProt/SwissProt
Match: sp|Q64535|ATP7B_RAT (Copper-transporting ATPase 2 OS=Rattus norvegicus OX=10116 GN=Atp7b PE=1 SV=1)

HSP 1 Score: 822.772 bits (2124), Expect = 0.000e+0
Identity = 448/911 (49.18%), Postives = 604/911 (66.30%), Query Frame = 1

Query:  304 KCHMRIQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMGFDAEIFQFKEHTKDIIEVMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKLAPKKTNKYN-DHVGESIKKWKHSFLISLIFGVPTMIVMMVFMYGFSHRMQVIHLKNGINVTVMVSNAPIXXXXXXXXXXXXXXXXXPVQFYGARYFYVQAYKSIKHGSANMDVLVVMATSVSYIYSFIVILVSMILRQDSSPQTFFETTPMLIVFLSLGRWLEHIAKGKTSEALSKLLSLQAFEATIIV--NDN---QERKISXXXXXXXXXXXXXPGEKIPIDGRVVSGKSRCDESLITGESMSVEKIPGSDVIGGTLNISGMLIIRATLVGEDSALNQIVKLVEEAQTSKAPIQELADKVAGLFVPGVIICSMFTLLIWIAIGYTNPNLLPGH---SSINTDNTELIWKYAFQLAITVLSVACPCSLGLATPTAVMVGTGVGAINGILIKGGVPLEKMHQLDVIVFDKTGTITTGKPSVTNFVMCVENVTSQIRNCILLMLGAAESSSEHPIGKAILQYVRETCDINEMPQVVHSKSVSGFGLECSLKLQSDMFVPDSEIDNVLVKINDFQENNLTENLKETSVKWRKINE---PVEVVLYLGNRNMMKENHISIPDKLDELMSRDEDNGRTVVLMAIDKVLLAMISIADQVKKEAALVVYTLEKMGVEVFLLTGDNHKTATAIAKEIGIRNVFAEVLPSHKVAKIQQIQNMSKYKRSWLFSCCSKPSKLTNVAMVGDGINDSPALAQADVGIAIGTGTDVAVEAADVVLIRNSLLDVIAAMKLSKDTVRRIRQNFVAATMYNLIGIPIAAGALMPIGVVFMPWMA 3000
            KC ++I+GMTC+SCV  IE  + +  G+ S L+ L+S   EV YDP++I +  IA  I D+GF+A I +    ++  IE++I GMTC+SCV+ IESKL +  GI    VAL T K   KFDP+II PRDI+  IEE+GF A LA +  N ++ DH  E IK+WK SFL SL+FG+P M +M+  +   S   + + L + I   + V N                     VQF G  YFYVQAYKS++H SANMDVL+V+AT+++Y YS ++++V++  + + SP TFF+T PML VF++LGRWLEH+AK KTSEAL+KL+SLQA EAT++    DN   +E ++ ++LV++GD++KV+PG K P+DG+V+ G +  DESLITGE+M V K PGS VI G++N  G ++I+AT VG D+ L QIVKLVEEAQ SKAPIQ+LAD+ +G FVP +II S  TL++WI IG+ +  ++  +    S +   TE+I ++AFQ +ITVL +ACPCSLGLATPTAVMVGTGV A NG+LIKGG PLE  H++  ++FDKTGTIT G P V  F++ V+  T  +R  +L ++G AE+SSEHP+G A+ +Y +E      +      ++V G G+ C +          S ++++L         +         V    I E   P    + +GNR  M+ N ++I   + + M+  E  G+T +L+AID VL  MI+IAD VK EAAL   TL+ MGV+V L+TGDN KTA AIA ++GI  VFAEVLPSHKVAK+Q++QN  K                  VAMVGDG+NDSPALAQADVGIAIGTGTDVA++AADVVLIRN LLDV+A++ LSK TVRRIR N V A +YN++GIPIAAG  MPIG+V  PWM 
Sbjct:  482 KCFVQIKGMTCASCVSNIERSLQRHAGILSVLVALMSGKAEVKYDPEVIQSPRIAQLIEDLGFEAAIMEDNTVSEGDIELIITGMTCASCVHNIESKLTRTNGITYASVALATSKAHVKFDPEIIGPRDIIKVIEEIGFHASLAHRNPNAHHLDHKTE-IKQWKKSFLCSLVFGIPVMGLMIYMLIPSSKPHETMVLDHNIIPGLSVLNLIFFILCTF------------VQFLGGWYFYVQAYKSLRHKSANMDVLIVLATTIAYAYSLVILVVAIAEKAEKSPVTFFDTPPMLFVFIALGRWLEHVAKSKTSEALAKLMSLQATEATVVTLGEDNLILREEQVPMELVQRGDIIKVVPGGKFPVDGKVLEGNTMADESLITGEAMPVTKKPGSIVIAGSINAHGSVLIKATHVGNDTTLAQIVKLVEEAQMSKAPIQQLADRFSGYFVPFIIIISTLTLVVWIIIGFVDFGIVQKYFPSPSKHISQTEVIIRFAFQTSITVLCIACPCSLGLATPTAVMVGTGVAAQNGVLIKGGKPLEMAHKIKTVMFDKTGTITHGVPRVMRFLLLVDVATLSLRK-VLAVVGTAEASSEHPLGVAVTKYCKEELGTETLGYSTDFQAVPGCGISCKV----------SNVESILA--------HRGPTAHPIGVGNPPIGEGTGPQTFSVLIGNREWMRRNGLTISSDISDAMTDHEMKGQTAILVAIDGVLCGMIAIADAVKPEAALASITLKSMGVDVALITGDNRKTARAIATQVGINKVFAEVLPSHKVAKVQELQNKGK-----------------KVAMVGDGVNDSPALAQADVGIAIGTGTDVAIDAADVVLIRNDLLDVVASIHLSKRTVRRIRVNLVLALIYNMVGIPIAAGVFMPIGIVLQPWMG 1343

HSP 2 Score: 103.99 bits (258), Expect = 4.816e-21
Identity = 56/163 (34.36%), Postives = 91/163 (55.83%), Query Frame = 1

Query:  319 IQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMGFDAEIFQFKEHT---------KDIIEVMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDA---------KLAPKKTNK 753
            I GMTC SCV +IE+++  LKG+ S  ++L      V Y P ++    I   I DMGF+A   + K  +         + ++++ ++GMTC SCV +IE K+ ++QG++ VKV+L+ ++    + P +I P D+ D I +MGF+A         +L P   NK
Sbjct:   63 ILGMTCHSCVKSIEDRISSLKGIVSIKVSLEQGSATVKYVPSVLNLQQICLQIEDMGFEASAAEGKAASWPSRSSPAQEAVVKLRVEGMTCQSCVSSIEGKIRKLQGVVRVKVSLSNQEAVITYQPYLIQPEDLRDHICDMGFEAAIKNRTAPLRLGPIDINK 225

HSP 3 Score: 83.9593 bits (206), Expect = 7.511e-15
Identity = 61/248 (24.60%), Postives = 107/248 (43.15%), Query Frame = 1

Query:  112 LKIIEDFFQFNDNIKTVVIDYEKNLVRICCHNDNCTYLTLCEAIENLGFLIN---------KNKETDNTKELFKCHMRIQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMGFDAEI-----------------------------------FQFKEHTKD---IIEVMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEM 714
            +K IED       I ++ +  E+    +           +C  IE++GF  +          ++ +   + + K  +R++GMTC SCV +IE ++ KL+GV    ++L +    +TY P LI   D+ D I DMGF+A I                                    +   H ++    + + I GM C SCV  IE  + Q+ G+ ++ V+L  +  + ++D   I+P  +  AIE +
Sbjct:   72 VKSIEDRISSLKGIVSIKVSLEQGSATVKYVPSVLNLQQICLQIEDMGFEASAAEGKAASWPSRSSPAQEAVVK--LRVEGMTCQSCVSSIEGKIRKLQGVVRVKVSLSNQEAVITYQPYLIQPEDLRDHICDMGFEAAIKNRTAPLRLGPIDINKLESTNLKRAAVPPIQNSNHLETPGHQQNHLATLPLRIDGMHCKSCVLNIEGNIGQLPGVQNIHVSLENKTAQVQYDSSCITPLFLQTAIEAL 317

HSP 4 Score: 63.929 bits (154), Expect = 1.061e-8
Identity = 43/181 (23.76%), Postives = 77/181 (42.54%), Query Frame = 1

Query:  313 MRIQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDM-----------GFDAEIFQFKEHTKDIIEVMIQGMTCSSCVYTI------------ESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKLAPKKTNKYNDHVGESIKK 786
            +RI GM C SCV  IE  + +L GV++  ++L +   +V YD   I    +   I  +           G + E       +    +   +   C + V TI            E  L+QM+G+  + ++L    G   +DP ++S  ++  A+E+MGF+  + P+         G S+ +
Sbjct:  260 LRIDGMHCKSCVLNIEGNIGQLPGVQNIHVSLENKTAQVQYDSSCITPLFLQTAIEALPPGYFKVSLPDGLEKESGSSSVPSLGSSQRQQEPGPCRTAVLTITGIPRDSSVQPMEDMLSQMKGVQQIDISLAEGTGAVLYDPSVVSSDELRTAVEDMGFEVSVNPENITTNRVSSGNSVPQ 440

HSP 5 Score: 61.6178 bits (148), Expect = 4.823e-8
Identity = 32/92 (34.78%), Postives = 51/92 (55.43%), Query Frame = 1

Query:  229 LCEAIENLGFLINKNKETDNTKELFKCHMRIQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMGFDAEI 504
            + + IE+LGF        DNT       + I GMTC+SCVH IE+++ +  G+  A + L ++   V +DP++I   DI   I ++GF A +
Sbjct:  535 IAQLIEDLGF--EAAIMEDNTVSEGDIELIITGMTCASCVHNIESKLTRTNGITYASVALATSKAHVKFDPEIIGPRDIIKVIEEIGFHASL 624

HSP 6 Score: 59.3066 bits (142), Expect = 2.707e-7
Identity = 28/72 (38.89%), Postives = 45/72 (62.50%), Query Frame = 1

Query:  541 VMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKLAPKKTNKY 756
            V I GMTC SCV +IE +++ ++GI+S+KV+L       K+ P +++ + I   IE+MGF+A  A  K   +
Sbjct:   61 VSILGMTCHSCVKSIEDRISSLKGIVSIKVSLEQGSATVKYVPSVLNLQQICLQIEDMGFEASAAEGKAASW 132

[Close]

BLAST of Copper-transporting ATPase 1 vs. UniProt/SwissProt
Match: sp|P35670|ATP7B_HUMAN (Copper-transporting ATPase 2 OS=Homo sapiens OX=9606 GN=ATP7B PE=1 SV=4)

HSP 1 Score: 821.231 bits (2120), Expect = 0.000e+0
Identity = 450/931 (48.34%), Postives = 611/931 (65.63%), Query Frame = 1

Query:  259 LINKNKETDNTKELFKCHMRIQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMGFDAEIFQFKEHTKDIIEVMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKLAPKKTNKYN-DHVGESIKKWKHSFLISLIFGVPTMIVMMVFMYGFSHRMQVIHLKNGINVTVMVSNAPIXXXXXXXXXXXXXXXXXPVQFYGARYFYVQAYKSIKHGSANMDVLVVMATSVSYIYSFIVILVSMILRQDSSPQTFFETTPMLIVFLSLGRWLEHIAKGKTSEALSKLLSLQAFEATIIV--NDN---QERKISXXXXXXXXXXXXXPGEKIPIDGRVVSGKSRCDESLITGESMSVEKIPGSDVIGGTLNISGMLIIRATLVGEDSALNQIVKLVEEAQTSKAPIQELADKVAGLFVPGVIICSMFTLLIWIAIG----------YTNPNLLPGHSSINTDNTELIWKYAFQLAITVLSVACPCSLGLATPTAVMVGTGVGAINGILIKGGVPLEKMHQLDVIVFDKTGTITTGKPSVTNFVMCVENVTSQIRNCILLMLGAAESSSEHPIGKAILQYVRETCDINEMPQVVHSKSVSGFGLECSLKLQSDMFVPDSEIDNVLVKINDFQENNLTENLKET-SVKWRKINEPVEVVLYLGNRNMMKENHISIPDKLDELMSRDEDNGRTVVLMAIDKVLLAMISIADQVKKEAALVVYTLEKMGVEVFLLTGDNHKTATAIAKEIGIRNVFAEVLPSHKVAKIQQIQNMSKYKRSWLFSCCSKPSKLTNVAMVGDGINDSPALAQADVGIAIGTGTDVAVEAADVVLIRNSLLDVIAAMKLSKDTVRRIRQNFVAATMYNLIGIPIAAGALMPIGVVFMPWMA 3000
            ++ K+ ++       KC ++I+GMTC+SCV  IE  + K  GV S L+ L++   E+ YDP++I   +IA  I D+GF+A + +    +   IE+ I GMTC+SCV+ IESKL +  GI    VAL T K   KFDP+II PRDI+  IEE+GF A LA +  N ++ DH  E IK+WK SFL SL+FG+P M +M+  +   +   Q + L + I   + + N                     VQ  G  YFYVQAYKS++H SANMDVL+V+ATS++Y+YS ++++V++  + + SP TFF+T PML VF++LGRWLEH+AK KTSEAL+KL+SLQA EAT++    DN   +E ++ ++LV++GD+VKV+PG K P+DG+V+ G +  DESLITGE+M V K PGS VI G++N  G ++I+AT VG D+ L QIVKLVEEAQ SKAPIQ+LAD+ +G FVP +II S  TL++WI IG          + NPN        +   TE+I ++AFQ +ITVL +ACPCSLGLATPTAVMVGTGV A NGILIKGG PLE  H++  ++FDKTGTIT G P V   ++  +  T  +R  +L ++G AE+SSEHP+G A+ +Y +E      +      ++V G G+ C +          S ++ +L   ++   +    +L E  S+   K   P    + +GNR  ++ N ++I   + + M+  E  G+T +L+AID VL  MI+IAD VK+EAAL V+TL+ MGV+V L+TGDN KTA AIA ++GI  VFAEVLPSHKVAK+Q++QN  K                  VAMVGDG+NDSPALAQAD+G+AIGTGTDVA+EAADVVLIRN LLDV+A++ LSK TVRRIR N V A +YNL+GIPIAAG  MPIG+V  PWM 
Sbjct:  474 ILAKSPQSTRAVAPQKCFLQIKGMTCASCVSNIERNLQKEAGVLSVLVALMAGKAEIKYDPEVIQPLEIAQFIQDLGFEAAVMEDYAGSDGNIELTITGMTCASCVHNIESKLTRTNGITYASVALATSKALVKFDPEIIGPRDIIKIIEEIGFHASLAQRNPNAHHLDHKME-IKQWKKSFLCSLVFGIPVMALMIYMLIPSNEPHQSMVLDHNIIPGLSILNLIFFILCTF------------VQLLGGWYFYVQAYKSLRHRSANMDVLIVLATSIAYVYSLVILVVAVAEKAERSPVTFFDTPPMLFVFIALGRWLEHLAKSKTSEALAKLMSLQATEATVVTLGEDNLIIREEQVPMELVQRGDIVKVVPGGKFPVDGKVLEGNTMADESLITGEAMPVTKKPGSTVIAGSINAHGSVLIKATHVGNDTTLAQIVKLVEEAQMSKAPIQQLADRFSGYFVPFIIIMSTLTLVVWIVIGFIDFGVVQRYFPNPNK-------HISQTEVIIRFAFQTSITVLCIACPCSLGLATPTAVMVGTGVAAQNGILIKGGKPLEMAHKIKTVMFDKTGTITHGVPRVMRVLLLGDVATLPLRK-VLAVVGTAEASSEHPLGVAVTKYCKEELGTETLGYCTDFQAVPGCGIGCKV----------SNVEGILAH-SERPLSAPASHLNEAGSLPAEKDAVPQTFSVLIGNREWLRRNGLTISSDVSDAMTDHEMKGQTAILVAIDGVLCGMIAIADAVKQEAALAVHTLQSMGVDVVLITGDNRKTARAIATQVGINKVFAEVLPSHKVAKVQELQNKGK-----------------KVAMVGDGVNDSPALAQADMGVAIGTGTDVAIEAADVVLIRNDLLDVVASIHLSKRTVRRIRINLVLALIYNLVGIPIAAGVFMPIGIVLQPWMG 1355

HSP 2 Score: 112.079 bits (279), Expect = 1.571e-23
Identity = 53/152 (34.87%), Postives = 91/152 (59.87%), Query Frame = 1

Query:  313 MRIQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMGFDAEIFQFKEHT---------KDIIEVMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKLAPK 741
            +RI GMTC SCV +IE+++  LKG+ S  ++L      V Y P ++    +   I DMGF+A I + K  +         + ++++ ++GMTC SCV +IE K+ ++QG++ VKV+L+ ++    + P +I P D+ D + +MGF+A +  K
Sbjct:   62 VRILGMTCQSCVKSIEDRISNLKGIISMKVSLEQGSATVKYVPSVVCLQQVCHQIGDMGFEASIAEGKAASWPSRSLPAQEAVVKLRVEGMTCQSCVSSIEGKVRKLQGVVRVKVSLSNQEAVITYQPYLIQPEDLRDHVNDMGFEAAIKSK 213

HSP 3 Score: 83.1889 bits (204), Expect = 1.084e-14
Identity = 51/180 (28.33%), Postives = 82/180 (45.56%), Query Frame = 1

Query:  310 HMRIQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLI----------------MASDIADTINDMGFDAEIFQFK----------EHTKDIIEVMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKLAPK--KTNKYNDH 765
             +RI GM C SCV  IE  + +L GV+S  ++L +   +V YDP                       + D     G D                 + T     + I GMTC+SCV++IE  ++Q++G+  + V+L        ++P +ISP ++  AIE+MGF+A +  +   TN   +H
Sbjct:  260 QLRIDGMHCKSCVLNIEENIGQLLGVQSIQVSLENKTAQVKYDPSCTSPVALQRAIEALPPGNFKVSLPDGAEGSGTDHRSSSSHSPGSPPRNQVQGTCSTTLIAIAGMTCASCVHSIEGMISQLEGVQQISVSLAEGTATVLYNPSVISPEELRAAIEDMGFEASVVSESCSTNPLGNH 439

HSP 4 Score: 58.151 bits (139), Expect = 5.565e-7
Identity = 26/72 (36.11%), Postives = 44/72 (61.11%), Query Frame = 1

Query:  541 VMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKLAPKKTNKY 756
            V I GMTC SCV +IE +++ ++GI+S+KV+L       K+ P ++  + +   I +MGF+A +A  K   +
Sbjct:   62 VRILGMTCQSCVKSIEDRISNLKGIISMKVSLEQGSATVKYVPSVVCLQQVCHQIGDMGFEASIAEGKAASW 133

[Close]

BLAST of Copper-transporting ATPase 1 vs. UniProt/SwissProt
Match: sp|P70705|ATP7A_RAT (Copper-transporting ATPase 1 OS=Rattus norvegicus OX=10116 GN=Atp7a PE=1 SV=1)

HSP 1 Score: 820.846 bits (2119), Expect = 0.000e+0
Identity = 487/1027 (47.42%), Postives = 665/1027 (64.75%), Query Frame = 1

Query:  229 LCEAIENLGF-----------------------LINKNKETDN--TKELFKCHMRIQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMGFDAEIFQFKEHTKDIIEVMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKLAPK-KTNKYNDHVGESIKKWKHSFLISLIFGVPTMIVMMVFMYGFSHRMQVIHLKNGINVTVMVSNAPIXXXXX-----XXXXXXXXXXXXPVQFYGARYFYVQAYKSIKHGSANMDVLVVMATSVSYIYSFIVILVSMILRQDSSPQTFFETTPMLIVFLSLGRWLEHIAKGKTSEALSKLLSLQAFEATIIVNDNQ-----ERKISXXXXXXXXXXXXXPGEKIPIDGRVVSGKSRCDESLITGESMSVEKIPGSDVIGGTLNISGMLIIRATLVGEDSALNQIVKLVEEAQTSKAPIQELADKVAGLFVPGVIICSMFTLLIWIAIGYTNPNLL----PGHSSINTDNTELIWKYAFQLAITVLSVACPCSLGLATPTAVMVGTGVGAINGILIKGGVPLEKMHQLDVIVFDKTGTITTGKPSVTNFVMCVENVTSQI-RNCILLMLGAAESSSEHPIGKAILQYVRETCDINEMPQVVHSKSVSGFGLEC------SLKLQSDMFVPDSEIDNV-LVKINDFQENNLTENLKETSVKWRKINEPVEVVLYLGNRNMMKENHISIPDKLDELMSRDEDNGRTVVLMAIDKVLLAMISIADQVKKEAALVVYTLEKMGVEVFLLTGDNHKTATAIAKEIGIRNVFAEVLPSHKVAKIQQIQNMSKYKRSWLFSCCSKPSKLTNVAMVGDGINDSPALAQADVGIAIGTGTDVAVEAADVVLIRNSLLDVIAAMKLSKDTVRRIRQNFVAATMYNLIGIPIAAGALMPIGVVFMPWMASVAMAASSICVVCXXXXXXXXXXPNEDQLANQEFKNHLECLKYGDMEVGVNLGKD 3165
            L EAIE++GF                       L+    E +N  T    KC++++ GMTC+SCV  IE  + + +G+ S L+ L++   EV Y+P +I    IA+ I ++GF A + +       I+E++++GMTC+SCV+ IES L + +GI    VAL T K   K+DP+II PRDI+  I  +GF+A L  K ++  + DH  E IK+W+ SFL+SL F +P M +M+  M    H   + H +N  N  ++  ++ +          S+ NLL  L   PVQF G  YFY+QAYK+++H +ANMDVL+V+AT++++ YS +++LV+M  R   +P TFF+T PML VF++LGRWLEHIAKGKTSEAL+KL+SLQA EATI+  +++     E ++ V+LV++GD++KV+PG K P+DGRV+ G S  DESLITGE+M V K PGS VI G++N +G L+IRAT VG D+ L+QIVKLVEEAQTSKAPIQ+ ADK++G FVP +++ S+ TLL+WI IG+ N  ++    PG++  +   TE I ++AFQ +ITVL +ACPCSLGLATPTAVMVGTGVGA NGILIKGG PLE  H++ V+VFDKTGTIT G P V    + VE  +++I RN IL ++G AES+SEHP+G A+ +Y ++  D   +      + V G G+ C       L  +S++ + ++ I N  LV+I+   E +   +               +  + +GNR  M  N + I + +DE M   E  GRT VL+ ID  L  +I+IAD VK EA L V+ L+ MG+EV L+TGDN KTA +IA ++GI  VFAEVLPSHKVAK++Q+Q   K                  VAMVGDGINDSPALA A VGIAIGTGTDVA+EAADVVLIRN LLDV+A++ LS+ TV+RIR NFV A +YNLIGIPIAAG  +PIG+V  PWM S AMAASS+ VV  SL LKL++KP  D   N E +      +    E+ V++G D
Sbjct:  431 LREAIEDMGFDAVLPADMKEPLVVIAQPSLETPLLPSTTEPENVMTPVQNKCYIQVSGMTCASCVANIERNLRREEGIYSVLVALMAGKAEVRYNPAVIQPRVIAELIRELGFGAVVMENAGEGNGILELVVRGMTCASCVHKIESTLTKHKGIFYCSVALATNKAHIKYDPEIIGPRDIIHTIGNLGFEASLVKKDRSANHLDHKRE-IKQWRGSFLVSLFFCIPVMGLMIYMMVMDHHLATLNHNQNMSNEEMINMHSSMFLERQILPGLSIMNLLSLLLCLPVQFCGGWYFYIQAYKALRHKTANMDVLIVLATTIAFAYSLVILLVAMYERAKVNPITFFDTPPMLFVFIALGRWLEHIAKGKTSEALAKLISLQATEATIVTLNSENLLLSEEQVDVELVQRGDIIKVVPGGKFPVDGRVIEGHSMVDESLITGEAMPVAKKPGSTVIAGSINQNGSLLIRATHVGADTTLSQIVKLVEEAQTSKAPIQQFADKLSGYFVPFIVLVSIVTLLVWIIIGFQNFEIVEAYFPGYNR-SISRTETIIRFAFQASITVLCIACPCSLGLATPTAVMVGTGVGAQNGILIKGGEPLEMAHKVKVVVFDKTGTITHGTPVVNQVKVLVE--SNKISRNKILAIVGTAESNSEHPLGAAVTKYCKQELDTETLGTCTDFQVVPGCGISCKVTNIEGLLHKSNLKIEENNIKNASLVQIDAINEQSSPSSSMIIDAHLSNAVNTQQYKVLIGNREWMIRNGLVISNDVDESMIEHERRGRTAVLVTIDDELCGLIAIADTVKPEAELAVHILKSMGLEVVLMTGDNSKTARSIASQVGITKVFAEVLPSHKVAKVKQLQEEGK-----------------RVAMVGDGINDSPALAMASVGIAIGTGTDVAIEAADVVLIRNDLLDVVASIDLSRKTVKRIRINFVFALIYNLIGIPIAAGVFLPIGLVLQPWMGSAAMAASSVSVVLSSLFLKLYRKPTYD---NYELRPRSHTGQRSPSEISVHVGID 1433

HSP 2 Score: 100.523 bits (249), Expect = 6.818e-20
Identity = 59/165 (35.76%), Postives = 84/165 (50.91%), Query Frame = 1

Query:  313 MRIQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMGFDAEI-FQFKEHTKDIIE--------------------------VMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDA 726
            + I GMTC+SCV +IE  + K  GVKS  ++L ++ G + YDP L     + + I DMGFDA +    KE    I +                          + + GMTC+SCV  IE  L + +GI SV VAL   K + +++P +I PR I + I E+GF A
Sbjct:  381 ININGMTCNSCVQSIEGVISKKPGVKSIHVSLTNSTGTIEYDPLLTSPEPLREAIEDMGFDAVLPADMKEPLVVIAQPSLETPLLPSTTEPENVMTPVQNKCYIQVSGMTCASCVANIERNLRREEGIYSVLVALMAGKAEVRYNPAVIQPRVIAELIRELGFGA 545

HSP 3 Score: 78.9518 bits (193), Expect = 2.260e-13
Identity = 50/162 (30.86%), Postives = 75/162 (46.30%), Query Frame = 1

Query:  313 MRIQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMGFDAEIFQFKEHTK------------------------------DIIEVMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIE 708
            MR++GMTC SC  TIE +V KL+GV+   ++L +    + Y P LI A +I   I  +GF A I +  ++ K                                I   I GM C SCV  IES L+ +Q + S+ V+L       K++  +++P  +  AIE
Sbjct:  175 MRVEGMTCHSCTSTIEGKVGKLQGVQRIKVSLDNQEATIVYQPHLITAEEIKKQIEAVGFPAFIKKQPKYLKLGAIDVERLKSTPVKSSEGSQQKSPAYPSDSAITFTIDGMHCKSCVSNIESALSTLQYVSSIVVSLENRSAIVKYNASLVTPEILRKAIE 336

HSP 4 Score: 75.8702 bits (185), Expect = 2.007e-12
Identity = 56/190 (29.47%), Postives = 94/190 (49.47%), Query Frame = 1

Query:  226 TLCEAIENLGF---LINKNKETDNTKELFKCHMRIQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMGFDAEIFQFKEHTKD----------IIEVMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKLAPKKTNKY 756
            TL EAI+++GF   L N N     T  +F   + +         H I++ +LK KGV    I+       VT  P ++ A+ I + + D+  D    + K  T +          ++++ ++GMTC SC  TIE K+ ++QG+  +KV+L  ++    + P +I+  +I   IE +GF A +  KK  KY
Sbjct:   61 TLQEAIDDMGFDALLHNANPLPVLTNTVF---LTVTAPLALPWDH-IQSTLLKTKGVTGVKISPQQRSAVVTIIPSVVSANQIVELVPDLSLDMGTQEKKSGTSEEHSTPQAGEVLLKMRVEGMTCHSCTSTIEGKVGKLQGVQRIKVSLDNQEATIVYQPHLITAEEIKKQIEAVGFPAFI--KKQPKY 244

HSP 5 Score: 74.7146 bits (182), Expect = 5.136e-12
Identity = 48/163 (29.45%), Postives = 81/163 (49.69%), Query Frame = 1

Query:  319 IQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTIN-------DMGFDAEI------------------FQFKEHTKDIIEVMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKL 732
            I GM C SCV  IE+ +  L+ V S +++L +    V Y+  L+    +   I         +   +E+                     +  T++++ + I GMTC+SCV +IE  +++  G+ S+ V+LT   G  ++DP + SP  + +AIE+MGFDA L
Sbjct:  283 IDGMHCKSCVSNIESALSTLQYVSSIVVSLENRSAIVKYNASLVTPEILRKAIEAVSPGQYRVSISSEVESPTSSPSSSSLQKMPLNLVSQPLTQEVV-ININGMTCNSCVQSIEGVISKKPGVKSIHVSLTNSTGTIEYDPLLTSPEPLREAIEDMGFDAVL 444

HSP 6 Score: 67.781 bits (164), Expect = 5.671e-10
Identity = 42/155 (27.10%), Postives = 75/155 (48.39%), Query Frame = 1

Query:  319 IQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMGFDAEIFQFKEHTKDIIEVMIQG--MTCSSCVYT----IESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKLAPKKTNKYNDH 765
            ++GMTC SCV TIE Q+ K+ GV    ++L      V Y+P L     + + I+DMGFDA +     H  + + V+     +T ++ +      I+S L + +G+  VK++           P ++S   I++ + ++  D     KK+    +H
Sbjct:   14 VEGMTCISCVRTIEQQIGKVNGVHHIKVSLEEKSATVIYNPKLQTPKTLQEAIDDMGFDALL-----HNANPLPVLTNTVFLTVTAPLALPWDHIQSTLLKTKGVTGVKISPQQRSAVVTIIPSVVSANQIVELVPDLSLDMGTQEKKSGTSEEH 163

HSP 7 Score: 62.003 bits (149), Expect = 3.458e-8
Identity = 25/66 (37.88%), Postives = 46/66 (69.70%), Query Frame = 1

Query:  535 IEVMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKL 732
            I + ++GMTC SCV TIE ++ ++ G+  +KV+L  +     ++P++ +P+ + +AI++MGFDA L
Sbjct:   10 ITITVEGMTCISCVRTIEQQIGKVNGVHHIKVSLEEKSATVIYNPKLQTPKTLQEAIDDMGFDALL 75

[Close]

BLAST of Copper-transporting ATPase 1 vs. TrEMBL
Match: A0A2C9KDW4 (Uncharacterized protein OS=Biomphalaria glabrata OX=6526 GN=106066430 PE=3 SV=1)

HSP 1 Score: 903.279 bits (2333), Expect = 0.000e+0
Identity = 522/986 (52.94%), Postives = 679/986 (68.86%), Query Frame = 1

Query:  265 NKNKETDNTKELFKCHMRIQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMGFDAEIFQFKEHTKDIIEVMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKLAPK---KTNKYNDHVGESIKKWKHSFLISLIFGVPTMIVMMVFMYGF----SHRMQVIHLKNGINVTV--------MVSNAP--IXXXXXXXXXXXXXXXXXPVQFYGARYFYVQAYKSIKHGSANMDVLVVMATSVSYIYSFIVILVSMILRQDSSPQTFFETTPMLIVFLSLGRWLEHIAKGKTSEALSKLLSLQAFEATIIVNDN-----QERKISXXXXXXXXXXXXXPGEKIPIDGRVVSGKSRCDESLITGESMSVEKIPGSDVIGGTLNISGMLIIRATLVGEDSALNQIVKLVEEAQTSKAPIQELADKVAGLFVPGVIICSMFTLLIWIAIGYTNPNLLPGH--SSINTDNTELIWKYAFQLAITVLSVACPCSLGLATPTAVMVGTGVGAINGILIKGGVPLEKMHQLDVIVFDKTGTITTGKPSVTNFVMCVENVTSQIRNCILLMLGAAESSSEHPIGKAILQYVRETCDINEMPQVVHSKSVSGFGLECSLKLQSDMF--VPDSEIDNVLVKINDFQENN-LTENL----KETSVKWRKI----NEPVEVVLYLGNRNMMKENHISIPDKLDELMSRDEDNGRTVVLMAIDKVLLAMISIADQVKKEAALVVYTLEKMGVEVFLLTGDNHKTATAIAKEIGIRNVFAEVLPSHKVAKIQQIQNMSKYKRSWLFSCCSKPSKLTNVAMVGDGINDSPALAQADVGIAIGTGTDVAVEAADVVLIRNSLLDVIAAMKLSKDTVRRIRQNFVAATMYNLIGIPIAAGALMPIGVVFMPWMASVAMAASSICVVCXXXXXXXXXXPNEDQLANQEFKNHLE 3117
            N  K  D+ ++  KC++ I GMTC+SCV TIE  V K++GV   L++L++   EVTYDP  ++ S +A+ + D+GF A + + +   +   E+ I GMTCSSCV  IES++ +  GILS  VAL TE GKF FD ++  PRDI++AI+ +GF+AKL      + ++Y DH  E IK+W+ SFL SLIFG P+MI+MMVFM+G     SH M         N T         M  + P  ++ PGL   NLL+FL ++PVQF+G RYFYVQAYK +KH S NMDVLVVMAT++SY+YS  V++ +M+ +++SSP TFFETTPML+VF+SLGRWLEHIAKGKTSEAL+KL+SLQ  +A ++  D       E+ IS+DLV++GD++KV PG KIP+D +V+ G+S CDESLITGESM VEK  GS VIGG++N +GML++ AT VG D+ L+QIVKLVEEAQTSKAPIQ LADK+AG+FVP V I S+ TL++W+ IGYT+  LL  +     N   +E+I++ AF  AITVLS+ACPC+LGLATPTAVMVGTGVGA NGILIKGG PLE  H+L VIVFDKTGTIT G P V+   M V++ T       L + G AE+SSEHPI  AIL+YV+ET     + +V    +V G G++C +     +   +  SE++N   + N F   N L +NL    +ET+     I        E  + +GNR  M+ N + + D +D++M+  E  G T VL AID V++ M+++AD VK EA L VY L++MG++V LLTGDN KTA AIAK++GI  VFAEVLPSHKV KI+Q+Q                 +K   VAMVGDG+NDSPALAQADVGIAIGTGTDVAVEAAD+VLI+N LLDV AA+KLSK TVRRI  NF++A +YNL+GIPIAAG L PIG+   PWMAS AMA SS+ VV  SLLLK ++KP ++ L  QE+    E
Sbjct:  348 NATKAFDD-EDYEKCYLNISGMTCASCVATIEKNVGKMEGVHKILVSLMAQRAEVTYDPAYVLPSQVANKVEDLGFSASVAEGEAVGRGTCELTILGMTCSSCVNRIESEMKKKNGILSASVALATETGKFTFDSELTGPRDIIEAIKSLGFEAKLRTDDDMRASRY-DH-REEIKRWRTSFLWSLIFGGPSMIIMMVFMFGIPSQDSHDMTYNASDPHSNHTAEKPWSHEKMDGHYPQKMIIPGLDWLNLLMFLLATPVQFFGGRYFYVQAYKVLKHRSTNMDVLVVMATTISYLYSLAVLIAAMVQKEESSPMTFFETTPMLMVFISLGRWLEHIAKGKTSEALAKLISLQPADAVLVQVDKNFQILSEKVISLDLVQRGDILKVTPGGKIPVDAKVIFGQSACDESLITGESMPVEKSIGSPVIGGSINQNGMLLVEATYVGADTTLSQIVKLVEEAQTSKAPIQNLADKIAGIFVPVVSILSLVTLIVWVIIGYTDIKLLEKNYDPRTNIPKSEIIFEKAFLYAITVLSIACPCALGLATPTAVMVGTGVGATNGILIKGGEPLELTHKLKVIVFDKTGTITHGVPRVSRVSMFVKDKTCSFVK-FLAIAGTAETSSEHPIASAILKYVKETLLTESLGKVSEFSAVPGCGIKCKVSHLESILSGINLSEVNN---RKNKFGSQNILIDNLLYGIQETANLILDIPLGAESSQEFEVLIGNREWMQRNGLVVIDTMDQVMTEHEMQGHTAVLCAIDGVIVGMLAVADTVKSEAHLAVYELKRMGLDVILLTGDNLKTAKAIAKQVGITRVFAEVLPSHKVKKIKQLQ-----------------AKGVKVAMVGDGVNDSPALAQADVGIAIGTGTDVAVEAADIVLIKNDLLDVYAAIKLSKLTVRRIHINFISACIYNLLGIPIAAGMLTPIGIELRPWMASAAMALSSVSVVAASLLLKTFRKPRKETLLTQEYYKSYE 1309

HSP 2 Score: 119.783 bits (299), Expect = 2.415e-23
Identity = 66/226 (29.20%), Postives = 116/226 (51.33%), Query Frame = 1

Query:   85 IKEVNDKNQLKIIEDFFQFNDNIKTVVIDYEKNLVRICCHNDNCTYLTLCEAIENLGF--LINKNKETDNTKELFKCHMRIQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMGFDAEIFQ-FKEHTKDIIEVMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKLAPKKTNK 753
            I  ++D + +  +++  Q    + +  + +E     +       +   L EA    G+  ++   +E     E  +  + ++GMTC SCV  IE  + K+ G+KS  ++L +    +   P +I     A+ I+DMGFDA +        K ++++ ++GMTC SCV  IES ++   GIL++KV+LT +     F+P +  P  I   IE+MGFDA ++P  T+K
Sbjct:   11 IARLHDYSSVTDLKNLLQQQTGVYSAEVSFETKRAAVQYSPLQTSPPVLAEAAAKNGYPAMVKAIEEAQPFMEEMEVMVSVEGMTCMSCVRNIEGNISKVPGIKSISVSLENKNARLVIVPSIITPEAAAEAIDDMGFDANVISPSSSGDKAVVDIHVEGMTCQSCVKNIESNMSSKSGILNIKVSLTNKSAHVTFNPCVTVPLKIAQQIEDMGFDASVSPSNTDK 236

HSP 3 Score: 99.7525 bits (247), Expect = 2.882e-17
Identity = 63/205 (30.73%), Postives = 107/205 (52.20%), Query Frame = 1

Query:  151 IKTVVIDYEKNLVRICCHNDNCTYLTLCEAIENLGFLINK-NKETDNTKELFKCHMRIQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMGFDAEI----------FQFKEHTKDI-IEVM-IQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDA 726
            IK++ +  E    R+       T     EAI+++GF  N  +  +   K +   H  ++GMTC SCV  IE+ +    G+ +  ++L +    VT++P + +   IA  I DMGFDA +                 KD+  +V+ I+GMTC SCV  IE  + +   ++S+KV+L ++ G  ++ P +ISP  + + I++MGF+A
Sbjct:  113 IKSISVSLENKNARLVIVPSIITPEAAAEAIDDMGFDANVISPSSSGDKAVVDIH--VEGMTCQSCVKNIESNMSSKSGILNIKVSLTNKSAHVTFNPCVTVPLKIAQQIEDMGFDASVSPSNTDKSVLVSSSGSVKDVRTKVLNIRGMTCQSCVNNIEGVIGKHPSVVSIKVSLASQTGTIQYYPSLISPEKLCELIDDMGFEA 315

[Close]

BLAST of Copper-transporting ATPase 1 vs. TrEMBL
Match: A0A2C9KE23 (Uncharacterized protein OS=Biomphalaria glabrata OX=6526 GN=106066430 PE=3 SV=1)

HSP 1 Score: 902.508 bits (2331), Expect = 0.000e+0
Identity = 523/992 (52.72%), Postives = 680/992 (68.55%), Query Frame = 1

Query:  265 NKNKETDNTKELFKCHMRIQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMGFDAEIFQFKEHTKDIIEVMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKLAPK---KTNKYNDHVGESIKKWKHSFLISLIFGVPTMIVMMVFMYGF----SHRMQVIHLKNGINVTV--------MVSNAP--IXXXXXXXXXXXXXXXXXPVQFYGARYFYVQAYKSIKHGSANMDVLVVMATSVSYIYSFIVILVSMILRQDSSPQTFFETTPMLIVFLSLGRWLEHIAKGKTSEALSKLLSLQAFEATIIVNDN-----QERKISXXXXXXXXXXXXXPGEKIPIDGRVVSGKSRCDESLITGESMSVEKIPGSDVIGGTLNISGMLIIRATLVGEDSALNQIVKLVEEAQTSKAPIQELADKVAGLFVPGVIICSMFTLLIWIAIGYTNPNLLPGHSSI--------NTDNTELIWKYAFQLAITVLSVACPCSLGLATPTAVMVGTGVGAINGILIKGGVPLEKMHQLDVIVFDKTGTITTGKPSVTNFVMCVENVTSQIRNCILLMLGAAESSSEHPIGKAILQYVRETCDINEMPQVVHSKSVSGFGLECSLKLQSDMF--VPDSEIDNVLVKINDFQENN-LTENL----KETSVKWRKI----NEPVEVVLYLGNRNMMKENHISIPDKLDELMSRDEDNGRTVVLMAIDKVLLAMISIADQVKKEAALVVYTLEKMGVEVFLLTGDNHKTATAIAKEIGIRNVFAEVLPSHKVAKIQQIQNMSKYKRSWLFSCCSKPSKLTNVAMVGDGINDSPALAQADVGIAIGTGTDVAVEAADVVLIRNSLLDVIAAMKLSKDTVRRIRQNFVAATMYNLIGIPIAAGALMPIGVVFMPWMASVAMAASSICVVCXXXXXXXXXXPNEDQLANQEFKNHLE 3117
            N  K  D+ ++  KC++ I GMTC+SCV TIE  V K++GV   L++L++   EVTYDP  ++ S +A+ + D+GF A + + +   +   E+ I GMTCSSCV  IES++ +  GILS  VAL TE GKF FD ++  PRDI++AI+ +GF+AKL      + ++Y DH  E IK+W+ SFL SLIFG P+MI+MMVFM+G     SH M         N T         M  + P  ++ PGL   NLL+FL ++PVQF+G RYFYVQAYK +KH S NMDVLVVMAT++SY+YS  V++ +M+ +++SSP TFFETTPML+VF+SLGRWLEHIAKGKTSEAL+KL+SLQ  +A ++  D       E+ IS+DLV++GD++KV PG KIP+D +V+ G+S CDESLITGESM VEK  GS VIGG++N +GML++ AT VG D+ L+QIVKLVEEAQTSKAPIQ LADK+AG+FVP V I S+ TL++W+ IGYT+  LL  +  I        N   +E+I++ AF  AITVLS+ACPC+LGLATPTAVMVGTGVGA NGILIKGG PLE  H+L VIVFDKTGTIT G P V+   M V++ T       L + G AE+SSEHPI  AIL+YV+ET     + +V    +V G G++C +     +   +  SE++N   + N F   N L +NL    +ET+     I        E  + +GNR  M+ N + + D +D++M+  E  G T VL AID V++ M+++AD VK EA L VY L++MG++V LLTGDN KTA AIAK++GI  VFAEVLPSHKV KI+Q+Q                 +K   VAMVGDG+NDSPALAQADVGIAIGTGTDVAVEAAD+VLI+N LLDV AA+KLSK TVRRI  NF++A +YNL+GIPIAAG L PIG+   PWMAS AMA SS+ VV  SLLLK ++KP ++ L  QE+    E
Sbjct:  348 NATKAFDD-EDYEKCYLNISGMTCASCVATIEKNVGKMEGVHKILVSLMAQRAEVTYDPAYVLPSQVANKVEDLGFSASVAEGEAVGRGTCELTILGMTCSSCVNRIESEMKKKNGILSASVALATETGKFTFDSELTGPRDIIEAIKSLGFEAKLRTDDDMRASRY-DH-REEIKRWRTSFLWSLIFGGPSMIIMMVFMFGIPSQDSHDMTYNASDPHSNHTAEKPWSHEKMDGHYPQKMIIPGLDWLNLLMFLLATPVQFFGGRYFYVQAYKVLKHRSTNMDVLVVMATTISYLYSLAVLIAAMVQKEESSPMTFFETTPMLMVFISLGRWLEHIAKGKTSEALAKLISLQPADAVLVQVDKNFQILSEKVISLDLVQRGDILKVTPGGKIPVDAKVIFGQSACDESLITGESMPVEKSIGSPVIGGSINQNGMLLVEATYVGADTTLSQIVKLVEEAQTSKAPIQNLADKIAGIFVPVVSILSLVTLIVWVIIGYTDIKLLEKNYDIQNSTSPRTNIPKSEIIFEKAFLYAITVLSIACPCALGLATPTAVMVGTGVGATNGILIKGGEPLELTHKLKVIVFDKTGTITHGVPRVSRVSMFVKDKTCSFVK-FLAIAGTAETSSEHPIASAILKYVKETLLTESLGKVSEFSAVPGCGIKCKVSHLESILSGINLSEVNN---RKNKFGSQNILIDNLLYGIQETANLILDIPLGAESSQEFEVLIGNREWMQRNGLVVIDTMDQVMTEHEMQGHTAVLCAIDGVIVGMLAVADTVKSEAHLAVYELKRMGLDVILLTGDNLKTAKAIAKQVGITRVFAEVLPSHKVKKIKQLQ-----------------AKGVKVAMVGDGVNDSPALAQADVGIAIGTGTDVAVEAADIVLIKNDLLDVYAAIKLSKLTVRRIHINFISACIYNLLGIPIAAGMLTPIGIELRPWMASAAMALSSVSVVAASLLLKTFRKPRKETLLTQEYYKSYE 1315

HSP 2 Score: 119.783 bits (299), Expect = 2.506e-23
Identity = 66/226 (29.20%), Postives = 116/226 (51.33%), Query Frame = 1

Query:   85 IKEVNDKNQLKIIEDFFQFNDNIKTVVIDYEKNLVRICCHNDNCTYLTLCEAIENLGF--LINKNKETDNTKELFKCHMRIQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMGFDAEIFQ-FKEHTKDIIEVMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKLAPKKTNK 753
            I  ++D + +  +++  Q    + +  + +E     +       +   L EA    G+  ++   +E     E  +  + ++GMTC SCV  IE  + K+ G+KS  ++L +    +   P +I     A+ I+DMGFDA +        K ++++ ++GMTC SCV  IES ++   GIL++KV+LT +     F+P +  P  I   IE+MGFDA ++P  T+K
Sbjct:   11 IARLHDYSSVTDLKNLLQQQTGVYSAEVSFETKRAAVQYSPLQTSPPVLAEAAAKNGYPAMVKAIEEAQPFMEEMEVMVSVEGMTCMSCVRNIEGNISKVPGIKSISVSLENKNARLVIVPSIITPEAAAEAIDDMGFDANVISPSSSGDKAVVDIHVEGMTCQSCVKNIESNMSSKSGILNIKVSLTNKSAHVTFNPCVTVPLKIAQQIEDMGFDASVSPSNTDK 236

HSP 3 Score: 99.7525 bits (247), Expect = 2.815e-17
Identity = 63/205 (30.73%), Postives = 107/205 (52.20%), Query Frame = 1

Query:  151 IKTVVIDYEKNLVRICCHNDNCTYLTLCEAIENLGFLINK-NKETDNTKELFKCHMRIQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMGFDAEI----------FQFKEHTKDI-IEVM-IQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDA 726
            IK++ +  E    R+       T     EAI+++GF  N  +  +   K +   H  ++GMTC SCV  IE+ +    G+ +  ++L +    VT++P + +   IA  I DMGFDA +                 KD+  +V+ I+GMTC SCV  IE  + +   ++S+KV+L ++ G  ++ P +ISP  + + I++MGF+A
Sbjct:  113 IKSISVSLENKNARLVIVPSIITPEAAAEAIDDMGFDANVISPSSSGDKAVVDIH--VEGMTCQSCVKNIESNMSSKSGILNIKVSLTNKSAHVTFNPCVTVPLKIAQQIEDMGFDASVSPSNTDKSVLVSSSGSVKDVRTKVLNIRGMTCQSCVNNIEGVIGKHPSVVSIKVSLASQTGTIQYYPSLISPEKLCELIDDMGFEA 315

[Close]

BLAST of Copper-transporting ATPase 1 vs. TrEMBL
Match: A0A2C9KDZ0 (Uncharacterized protein OS=Biomphalaria glabrata OX=6526 GN=106066430 PE=3 SV=1)

HSP 1 Score: 902.508 bits (2331), Expect = 0.000e+0
Identity = 523/992 (52.72%), Postives = 680/992 (68.55%), Query Frame = 1

Query:  265 NKNKETDNTKELFKCHMRIQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMGFDAEIFQFKEHTKDIIEVMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKLAPK---KTNKYNDHVGESIKKWKHSFLISLIFGVPTMIVMMVFMYGF----SHRMQVIHLKNGINVTV--------MVSNAP--IXXXXXXXXXXXXXXXXXPVQFYGARYFYVQAYKSIKHGSANMDVLVVMATSVSYIYSFIVILVSMILRQDSSPQTFFETTPMLIVFLSLGRWLEHIAKGKTSEALSKLLSLQAFEATIIVNDN-----QERKISXXXXXXXXXXXXXPGEKIPIDGRVVSGKSRCDESLITGESMSVEKIPGSDVIGGTLNISGMLIIRATLVGEDSALNQIVKLVEEAQTSKAPIQELADKVAGLFVPGVIICSMFTLLIWIAIGYTNPNLLPGHSSI--------NTDNTELIWKYAFQLAITVLSVACPCSLGLATPTAVMVGTGVGAINGILIKGGVPLEKMHQLDVIVFDKTGTITTGKPSVTNFVMCVENVTSQIRNCILLMLGAAESSSEHPIGKAILQYVRETCDINEMPQVVHSKSVSGFGLECSLKLQSDMF--VPDSEIDNVLVKINDFQENN-LTENL----KETSVKWRKI----NEPVEVVLYLGNRNMMKENHISIPDKLDELMSRDEDNGRTVVLMAIDKVLLAMISIADQVKKEAALVVYTLEKMGVEVFLLTGDNHKTATAIAKEIGIRNVFAEVLPSHKVAKIQQIQNMSKYKRSWLFSCCSKPSKLTNVAMVGDGINDSPALAQADVGIAIGTGTDVAVEAADVVLIRNSLLDVIAAMKLSKDTVRRIRQNFVAATMYNLIGIPIAAGALMPIGVVFMPWMASVAMAASSICVVCXXXXXXXXXXPNEDQLANQEFKNHLE 3117
            N  K  D+ ++  KC++ I GMTC+SCV TIE  V K++GV   L++L++   EVTYDP  ++ S +A+ + D+GF A + + +   +   E+ I GMTCSSCV  IES++ +  GILS  VAL TE GKF FD ++  PRDI++AI+ +GF+AKL      + ++Y DH  E IK+W+ SFL SLIFG P+MI+MMVFM+G     SH M         N T         M  + P  ++ PGL   NLL+FL ++PVQF+G RYFYVQAYK +KH S NMDVLVVMAT++SY+YS  V++ +M+ +++SSP TFFETTPML+VF+SLGRWLEHIAKGKTSEAL+KL+SLQ  +A ++  D       E+ IS+DLV++GD++KV PG KIP+D +V+ G+S CDESLITGESM VEK  GS VIGG++N +GML++ AT VG D+ L+QIVKLVEEAQTSKAPIQ LADK+AG+FVP V I S+ TL++W+ IGYT+  LL  +  I        N   +E+I++ AF  AITVLS+ACPC+LGLATPTAVMVGTGVGA NGILIKGG PLE  H+L VIVFDKTGTIT G P V+   M V++ T       L + G AE+SSEHPI  AIL+YV+ET     + +V    +V G G++C +     +   +  SE++N   + N F   N L +NL    +ET+     I        E  + +GNR  M+ N + + D +D++M+  E  G T VL AID V++ M+++AD VK EA L VY L++MG++V LLTGDN KTA AIAK++GI  VFAEVLPSHKV KI+Q+Q                 +K   VAMVGDG+NDSPALAQADVGIAIGTGTDVAVEAAD+VLI+N LLDV AA+KLSK TVRRI  NF++A +YNL+GIPIAAG L PIG+   PWMAS AMA SS+ VV  SLLLK ++KP ++ L  QE+    E
Sbjct:  323 NATKAFDD-EDYEKCYLNISGMTCASCVATIEKNVGKMEGVHKILVSLMAQRAEVTYDPAYVLPSQVANKVEDLGFSASVAEGEAVGRGTCELTILGMTCSSCVNRIESEMKKKNGILSASVALATETGKFTFDSELTGPRDIIEAIKSLGFEAKLRTDDDMRASRY-DH-REEIKRWRTSFLWSLIFGGPSMIIMMVFMFGIPSQDSHDMTYNASDPHSNHTAEKPWSHEKMDGHYPQKMIIPGLDWLNLLMFLLATPVQFFGGRYFYVQAYKVLKHRSTNMDVLVVMATTISYLYSLAVLIAAMVQKEESSPMTFFETTPMLMVFISLGRWLEHIAKGKTSEALAKLISLQPADAVLVQVDKNFQILSEKVISLDLVQRGDILKVTPGGKIPVDAKVIFGQSACDESLITGESMPVEKSIGSPVIGGSINQNGMLLVEATYVGADTTLSQIVKLVEEAQTSKAPIQNLADKIAGIFVPVVSILSLVTLIVWVIIGYTDIKLLEKNYDIQNSTSPRTNIPKSEIIFEKAFLYAITVLSIACPCALGLATPTAVMVGTGVGATNGILIKGGEPLELTHKLKVIVFDKTGTITHGVPRVSRVSMFVKDKTCSFVK-FLAIAGTAETSSEHPIASAILKYVKETLLTESLGKVSEFSAVPGCGIKCKVSHLESILSGINLSEVNN---RKNKFGSQNILIDNLLYGIQETANLILDIPLGAESSQEFEVLIGNREWMQRNGLVVIDTMDQVMTEHEMQGHTAVLCAIDGVIVGMLAVADTVKSEAHLAVYELKRMGLDVILLTGDNLKTAKAIAKQVGITRVFAEVLPSHKVKKIKQLQ-----------------AKGVKVAMVGDGVNDSPALAQADVGIAIGTGTDVAVEAADIVLIKNDLLDVYAAIKLSKLTVRRIHINFISACIYNLLGIPIAAGMLTPIGIELRPWMASAAMALSSVSVVAASLLLKTFRKPRKETLLTQEYYKSYE 1290

HSP 2 Score: 117.472 bits (293), Expect = 1.126e-22
Identity = 62/178 (34.83%), Postives = 99/178 (55.62%), Query Frame = 1

Query:  229 LCEAIENLGF--LINKNKETDNTKELFKCHMRIQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMGFDAEIFQ-FKEHTKDIIEVMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKLAPKKTNK 753
            L EA    G+  ++   +E     E  +  + ++GMTC SCV  IE  + K+ G+KS  ++L +    +   P +I     A+ I+DMGFDA +        K ++++ ++GMTC SCV  IES ++   GIL++KV+LT +     F+P +  P  I   IE+MGFDA ++P  T+K
Sbjct:   34 LAEAAAKNGYPAMVKAIEEAQPFMEEMEVMVSVEGMTCMSCVRNIEGNISKVPGIKSISVSLENKNARLVIVPSIITPEAAAEAIDDMGFDANVISPSSSGDKAVVDIHVEGMTCQSCVKNIESNMSSKSGILNIKVSLTNKSAHVTFNPCVTVPLKIAQQIEDMGFDASVSPSNTDK 211

HSP 3 Score: 100.138 bits (248), Expect = 2.653e-17
Identity = 63/205 (30.73%), Postives = 107/205 (52.20%), Query Frame = 1

Query:  151 IKTVVIDYEKNLVRICCHNDNCTYLTLCEAIENLGFLINK-NKETDNTKELFKCHMRIQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMGFDAEI----------FQFKEHTKDI-IEVM-IQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDA 726
            IK++ +  E    R+       T     EAI+++GF  N  +  +   K +   H  ++GMTC SCV  IE+ +    G+ +  ++L +    VT++P + +   IA  I DMGFDA +                 KD+  +V+ I+GMTC SCV  IE  + +   ++S+KV+L ++ G  ++ P +ISP  + + I++MGF+A
Sbjct:   88 IKSISVSLENKNARLVIVPSIITPEAAAEAIDDMGFDANVISPSSSGDKAVVDIH--VEGMTCQSCVKNIESNMSSKSGILNIKVSLTNKSAHVTFNPCVTVPLKIAQQIEDMGFDASVSPSNTDKSVLVSSSGSVKDVRTKVLNIRGMTCQSCVNNIEGVIGKHPSVVSIKVSLASQTGTIQYYPSLISPEKLCELIDDMGFEA 290

[Close]

BLAST of Copper-transporting ATPase 1 vs. TrEMBL
Match: A0A2C9KDX7 (Uncharacterized protein OS=Biomphalaria glabrata OX=6526 GN=106066430 PE=3 SV=1)

HSP 1 Score: 902.123 bits (2330), Expect = 0.000e+0
Identity = 523/992 (52.72%), Postives = 680/992 (68.55%), Query Frame = 1

Query:  265 NKNKETDNTKELFKCHMRIQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMGFDAEIFQFKEHTKDIIEVMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKLAPK---KTNKYNDHVGESIKKWKHSFLISLIFGVPTMIVMMVFMYGF----SHRMQVIHLKNGINVTV--------MVSNAP--IXXXXXXXXXXXXXXXXXPVQFYGARYFYVQAYKSIKHGSANMDVLVVMATSVSYIYSFIVILVSMILRQDSSPQTFFETTPMLIVFLSLGRWLEHIAKGKTSEALSKLLSLQAFEATIIVNDN-----QERKISXXXXXXXXXXXXXPGEKIPIDGRVVSGKSRCDESLITGESMSVEKIPGSDVIGGTLNISGMLIIRATLVGEDSALNQIVKLVEEAQTSKAPIQELADKVAGLFVPGVIICSMFTLLIWIAIGYTNPNLLPGHSSI--------NTDNTELIWKYAFQLAITVLSVACPCSLGLATPTAVMVGTGVGAINGILIKGGVPLEKMHQLDVIVFDKTGTITTGKPSVTNFVMCVENVTSQIRNCILLMLGAAESSSEHPIGKAILQYVRETCDINEMPQVVHSKSVSGFGLECSLKLQSDMF--VPDSEIDNVLVKINDFQENN-LTENL----KETSVKWRKI----NEPVEVVLYLGNRNMMKENHISIPDKLDELMSRDEDNGRTVVLMAIDKVLLAMISIADQVKKEAALVVYTLEKMGVEVFLLTGDNHKTATAIAKEIGIRNVFAEVLPSHKVAKIQQIQNMSKYKRSWLFSCCSKPSKLTNVAMVGDGINDSPALAQADVGIAIGTGTDVAVEAADVVLIRNSLLDVIAAMKLSKDTVRRIRQNFVAATMYNLIGIPIAAGALMPIGVVFMPWMASVAMAASSICVVCXXXXXXXXXXPNEDQLANQEFKNHLE 3117
            N  K  D+ ++  KC++ I GMTC+SCV TIE  V K++GV   L++L++   EVTYDP  ++ S +A+ + D+GF A + + +   +   E+ I GMTCSSCV  IES++ +  GILS  VAL TE GKF FD ++  PRDI++AI+ +GF+AKL      + ++Y DH  E IK+W+ SFL SLIFG P+MI+MMVFM+G     SH M         N T         M  + P  ++ PGL   NLL+FL ++PVQF+G RYFYVQAYK +KH S NMDVLVVMAT++SY+YS  V++ +M+ +++SSP TFFETTPML+VF+SLGRWLEHIAKGKTSEAL+KL+SLQ  +A ++  D       E+ IS+DLV++GD++KV PG KIP+D +V+ G+S CDESLITGESM VEK  GS VIGG++N +GML++ AT VG D+ L+QIVKLVEEAQTSKAPIQ LADK+AG+FVP V I S+ TL++W+ IGYT+  LL  +  I        N   +E+I++ AF  AITVLS+ACPC+LGLATPTAVMVGTGVGA NGILIKGG PLE  H+L VIVFDKTGTIT G P V+   M V++ T       L + G AE+SSEHPI  AIL+YV+ET     + +V    +V G G++C +     +   +  SE++N   + N F   N L +NL    +ET+     I        E  + +GNR  M+ N + + D +D++M+  E  G T VL AID V++ M+++AD VK EA L VY L++MG++V LLTGDN KTA AIAK++GI  VFAEVLPSHKV KI+Q+Q                 +K   VAMVGDG+NDSPALAQADVGIAIGTGTDVAVEAAD+VLI+N LLDV AA+KLSK TVRRI  NF++A +YNL+GIPIAAG L PIG+   PWMAS AMA SS+ VV  SLLLK ++KP ++ L  QE+    E
Sbjct:  278 NATKAFDD-EDYEKCYLNISGMTCASCVATIEKNVGKMEGVHKILVSLMAQRAEVTYDPAYVLPSQVANKVEDLGFSASVAEGEAVGRGTCELTILGMTCSSCVNRIESEMKKKNGILSASVALATETGKFTFDSELTGPRDIIEAIKSLGFEAKLRTDDDMRASRY-DH-REEIKRWRTSFLWSLIFGGPSMIIMMVFMFGIPSQDSHDMTYNASDPHSNHTAEKPWSHEKMDGHYPQKMIIPGLDWLNLLMFLLATPVQFFGGRYFYVQAYKVLKHRSTNMDVLVVMATTISYLYSLAVLIAAMVQKEESSPMTFFETTPMLMVFISLGRWLEHIAKGKTSEALAKLISLQPADAVLVQVDKNFQILSEKVISLDLVQRGDILKVTPGGKIPVDAKVIFGQSACDESLITGESMPVEKSIGSPVIGGSINQNGMLLVEATYVGADTTLSQIVKLVEEAQTSKAPIQNLADKIAGIFVPVVSILSLVTLIVWVIIGYTDIKLLEKNYDIQNSTSPRTNIPKSEIIFEKAFLYAITVLSIACPCALGLATPTAVMVGTGVGATNGILIKGGEPLELTHKLKVIVFDKTGTITHGVPRVSRVSMFVKDKTCSFVK-FLAIAGTAETSSEHPIASAILKYVKETLLTESLGKVSEFSAVPGCGIKCKVSHLESILSGINLSEVNN---RKNKFGSQNILIDNLLYGIQETANLILDIPLGAESSQEFEVLIGNREWMQRNGLVVIDTMDQVMTEHEMQGHTAVLCAIDGVIVGMLAVADTVKSEAHLAVYELKRMGLDVILLTGDNLKTAKAIAKQVGITRVFAEVLPSHKVKKIKQLQ-----------------AKGVKVAMVGDGVNDSPALAQADVGIAIGTGTDVAVEAADIVLIKNDLLDVYAAIKLSKLTVRRIHINFISACIYNLLGIPIAAGMLTPIGIELRPWMASAAMALSSVSVVAASLLLKTFRKPRKETLLTQEYYKSYE 1245

HSP 2 Score: 115.931 bits (289), Expect = 3.221e-22
Identity = 57/154 (37.01%), Postives = 90/154 (58.44%), Query Frame = 1

Query:  295 ELFKCHMRIQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMGFDAEIFQ-FKEHTKDIIEVMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKLAPKKTNK 753
            E  +  + ++GMTC SCV  IE  + K+ G+KS  ++L +    +   P +I     A+ I+DMGFDA +        K ++++ ++GMTC SCV  IES ++   GIL++KV+LT +     F+P +  P  I   IE+MGFDA ++P  T+K
Sbjct:   13 EEMEVMVSVEGMTCMSCVRNIEGNISKVPGIKSISVSLENKNARLVIVPSIITPEAAAEAIDDMGFDANVISPSSSGDKAVVDIHVEGMTCQSCVKNIESNMSSKSGILNIKVSLTNKSAHVTFNPCVTVPLKIAQQIEDMGFDASVSPSNTDK 166

HSP 3 Score: 99.7525 bits (247), Expect = 3.284e-17
Identity = 63/205 (30.73%), Postives = 107/205 (52.20%), Query Frame = 1

Query:  151 IKTVVIDYEKNLVRICCHNDNCTYLTLCEAIENLGFLINK-NKETDNTKELFKCHMRIQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMGFDAEI----------FQFKEHTKDI-IEVM-IQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDA 726
            IK++ +  E    R+       T     EAI+++GF  N  +  +   K +   H  ++GMTC SCV  IE+ +    G+ +  ++L +    VT++P + +   IA  I DMGFDA +                 KD+  +V+ I+GMTC SCV  IE  + +   ++S+KV+L ++ G  ++ P +ISP  + + I++MGF+A
Sbjct:   43 IKSISVSLENKNARLVIVPSIITPEAAAEAIDDMGFDANVISPSSSGDKAVVDIH--VEGMTCQSCVKNIESNMSSKSGILNIKVSLTNKSAHVTFNPCVTVPLKIAQQIEDMGFDASVSPSNTDKSVLVSSSGSVKDVRTKVLNIRGMTCQSCVNNIEGVIGKHPSVVSIKVSLASQTGTIQYYPSLISPEKLCELIDDMGFEA 245

[Close]

BLAST of Copper-transporting ATPase 1 vs. TrEMBL
Match: A0A0L8GFT7 (Uncharacterized protein OS=Octopus bimaculoides OX=37653 GN=OCBIM_22034798mg PE=3 SV=1)

HSP 1 Score: 880.167 bits (2273), Expect = 0.000e+0
Identity = 535/1074 (49.81%), Postives = 705/1074 (65.64%), Query Frame = 1

Query:  109 QLKIIEDFFQFNDNIKTVVIDYEKNLVRICCHNDNCTYLTLCEAIENLGFLINKNKETDNTK------------------------------ELFKCHMRIQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMGFDAEIFQFKEHTKDIIEVMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKLAPKKTNK--YNDHVGESIKKWKHSFLISLIFGVPTMIVMMVFMYGFSHRMQVIHLKNGINVT-------------VMVSNAPIXXXXXXXXXXXXXXXXXPVQFYGARYFYVQAYKSIKHGSANMDVLVVMATSVSYIYSFIVILVSMILRQDSSPQTFFETTPMLIVFLSLGRWLEHIAKGKTSEALSKLLSLQAFEATIIV----NDNQERKISXXXXXXXXXXXXXPGEKIPIDGRVVSGKSRCDESLITGESMSVEKIPGSDVIGGTLNISGMLIIRATLVGEDSALNQIVKLVEEAQTSKAPIQELADKVAGLFVPGVIICSMFTLLIWIAIGYTNPNLLPGHSSINTDNT----ELIWKYAFQLAITVLSVACPCSLGLATPTAVMVGTGVGAINGILIKGGVPLEKMHQLDVIVFDKTGTITTGKPSVTNFVMCVE-NVTSQIRNCILLMLGAAESSSEHPIGKAILQYVRETCDINEMPQVVHSKSVSGFGLECSL-KLQSDMFVPDSE---------------IDNVLVKINDFQENNLTENLKETSVKWRKINEPVEVVLYLGNRNMMKENHISIPDKLDELMSRDEDNGRTVVLMAIDKVLLAMISIADQVKKEAALVVYTLEKMGVEVFLLTGDNHKTATAIAKEIGIRNVFAEVLPSHKVAKIQQIQNMSKYKRSWLFSCCSKPSKLTNVAMVGDGINDSPALAQADVGIAIGTGTDVAVEAADVVLIRNSLLDVIAAMKLSKDTVRRIRQNFVAATMYNLIGIPIAAGALMPIGVVFMPWMASVAMAASSICVVCXXXXXXXXXXPNEDQLANQE-FKNHLE 3117
            Q+KI E     + ++K++V+  + N   I  + D  +   LC AI+++GF  +  +E +                                 E  KC   + GMTC+SCV  IEN + K++GVK+ L+ L+S   EV YDP  I++S I + I+ +GF A + + +   +  +E++I GMTCSSCV+ IES L + +GI+S  VAL T KG F+F+ +    RDI+ AIEE+GF A LA +  NK    DH  E I++W+ SF  SL+FG+P M++MM FM+       +    N  NVT             +MV N       LSLENLLLF+ ++ VQ  GARYFYVQAY+S+KH SANMDVLV +A S+SY+YS +V++V++ LR+ SSP TFFETTPML++F+SLGRWLEHIAKGKTSEA++KLLSLQA EA ++     N  +E  I+VDLV++GD++KVLPGEKIP+D +V+ G S CDESLITGESM V K PG+ +IGG+LN  GML+I AT VG D+ L+QIVKLVEEAQ SKAPIQ+LADK+AG FVP V+  S+ TL+IWI IGY +  L+    S   D      ELI++YAFQ AITVLS+ACPC+LGLATPTAVMVGTGVGA NGILIKGG PLE  H++  IVFDKTGTIT G P V      VE +V S ++  +L + G AE+SSEHPI  AI++Y ++T     + QV    +V G GL C + +++S +   D E               IDN+L      +++ + E+++       +  +     +++GNR  M+ N + I  K++  M   E+ G TVVL AID  L+AM+++AD VK +A L V TL+ MG+EV LLTGDN KTA AIAK++GI  VFAEVLPSHKV KI+Q+Q  +K                  VAMVGDG+NDSPALAQADVGIAIGTGTDVAVEAAD+VLI+NSL+DV+AA+KLSK TVRRIR NF AA++YNL+GIPIAAG  MP+G+   PWMAS AMA SS+ VV LSLLLKL++KP +++L   E F+ H E
Sbjct:  351 QMKISE-----HSSVKSIVVSLKDNNAVIEYYPDTTSPSELCNAIDDMGFEASVAEEKNRNSMVKSPETNVAIDVGSSVVHFSSNDDALENIEYEKCFFVVTGMTCASCVALIENNISKVEGVKNVLVALMSQKAEVKYDPAYILSSQIGNKISALGFGATLLESESLGQSAVEIIITGMTCSSCVHLIESSLLKKKGIVSANVALATSKGVFEFNNETTGARDIIQAIEELGFQATLATESDNKAARYDHRME-IRRWRSSFFWSLLFGLPAMVIMMYFMFSMPAHDNLPPAGNATNVTTVAPGTFKTHRKQLMVCNG------LSLENLLLFILATAVQLLGARYFYVQAYRSLKHKSANMDVLVCLAISISYMYSTVVVIVAIALREPSSPVTFFETTPMLVLFISLGRWLEHIAKGKTSEAIAKLLSLQASEALLVYMKDGNIIKEETINVDLVQRGDILKVLPGEKIPVDAKVIEGLSSCDESLITGESMPVSKKPGASLIGGSLNQHGMLLIEATHVGTDTTLSQIVKLVEEAQVSKAPIQQLADKIAGYFVPMVVCVSLLTLIIWIIIGYHDIKLI--DKSFKEDGPLTKHELIFQYAFQYAITVLSIACPCALGLATPTAVMVGTGVGATNGILIKGGEPLELTHKVKNIVFDKTGTITHGIPRVARICTFVESHVCSFVK--LLAIAGTAETSSEHPIAAAIVKYAKQTLKTEILGQVTDFLAVPGCGLRCKVSRVESLLSSIDIEGVHNRRNMAGSQRVKIDNIL----GLEDSPIIESMEAVGATASQTYD-----VFIGNREWMRRNGLEITHKINNSMEEHEEQGHTVVLCAIDDELMAMLAVADTVKSDAHLAVSTLKDMGLEVILLTGDNQKTARAIAKQVGITTVFAEVLPSHKVKKIKQLQKSNK-----------------KVAMVGDGVNDSPALAQADVGIAIGTGTDVAVEAADIVLIQNSLIDVVAAIKLSKMTVRRIRINFFAASIYNLLGIPIAAGVFMPVGLSLRPWMASAAMALSSVTVVSLSLLLKLFRKPTKNELLTPEYFRRHCE 1382

HSP 2 Score: 108.612 bits (270), Expect = 6.151e-20
Identity = 63/208 (30.29%), Postives = 108/208 (51.92%), Query Frame = 1

Query:  151 IKTVVIDYEKNLVRICCHNDNCTYLTLCEAIENLGFLINKNKETDNTKELFKCHMRIQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMGFDAEIFQFKEHTKDIIEVM-------------IQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKLA 735
            + +V    +K+L  + C N   + L + EA+E +G  +N  K       L +  ++I GMTC SCV TIE+++ K  GV    ++L      + YD  +     + + I+DMGF+A + +      D  E+              I+GM+C+SCV  IE+ +++  GI  + V+L       K++P+ +SP  I +AI +MGFDA+++
Sbjct:  114 VNSVEFSKDKDLT-VYCQNSKISGLQISEALEAIGIEVNMKKMNQTQSFLSETIIQIDGMTCQSCVRTIESELSKFPGVDFISVSLEEKRAIIRYDQQVTNPQALRNKIDDMGFEAALTESDSSDVDFDEIAKRNVPAENLCIINIKGMSCNSCVTIIENTISEKAGINKITVSLENNNALVKYNPEKLSPETIAEAISDMGFDAEVS 320

HSP 3 Score: 97.8265 bits (242), Expect = 1.276e-16
Identity = 50/150 (33.33%), Postives = 87/150 (58.00%), Query Frame = 1

Query:  307 CHMRIQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMGFDAEIFQFKEHTK----DIIEVMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKLAPKK 744
            C + I+GM+C+SCV  IEN + +  G+    ++L +    V Y+P+ +    IA+ I+DMGFDAE+ +            + + I+GMTC SC  TI+ K+++   + S+ V+L       ++ P   SP ++ +AI++MGF+A +A +K
Sbjct:  254 CIINIKGMSCNSCVTIIENTISEKAGINKITVSLENNNALVKYNPEKLSPETIAEAISDMGFDAEVSKGDNPAAFNLIATVVINIKGMTCKSCQSTIQMKISEHSSVKSIVVSLKDNNAVIEYYPDTTSPSELCNAIDDMGFEASVAEEK 403

HSP 4 Score: 92.0485 bits (227), Expect = 6.522e-15
Identity = 67/252 (26.59%), Postives = 119/252 (47.22%), Query Frame = 1

Query:   79 ILIKEVNDKNQLKIIEDFFQFNDNIKTVVIDYEKNLVRICCHNDNCTYLTLCEAIENLGF--LINKNKETDNTKELFKCHMRIQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMGFDAEIFQFKEHTK------------------------DIIE--------VMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKL 732
            I IK ++  + + IIE+       I  + +  E N   +  + +  +  T+ EAI ++GF   ++K         +    + I+GMTC SC  TI+ ++ +   VKS +++L      + Y PD    S++ + I+DMGF+A + + K                            D +E         ++ GMTC+SCV  IE+ +++++G+ +V VAL ++K + K+DP  I    I + I  +GF A L
Sbjct:  256 INIKGMSCNSCVTIIENTISEKAGINKITVSLENNNALVKYNPEKLSPETIAEAISDMGFDAEVSKGDNPAAFNLIATVVINIKGMTCKSCQSTIQMKISEHSSVKSIVVSLKDNNAVIEYYPDTTSPSELCNAIDDMGFEASVAEEKNRNSMVKSPETNVAIDVGSSVVHFSSNDDALENIEYEKCFFVVTGMTCASCVALIENNISKVEGVKNVLVALMSQKAEVKYDPAYILSSQIGNKISALGFGATL 507

[Close]

BLAST of Copper-transporting ATPase 1 vs. Ensembl Cavefish
Match: atp7a (ATPase copper transporting alpha [Source:NCBI gene;Acc:103038584])

HSP 1 Score: 826.624 bits (2134), Expect = 0.000e+0
Identity = 459/944 (48.62%), Postives = 621/944 (65.78%), Query Frame = 1

Query:  250 LGFLINKNKETDNTKEL-----FKCHMRIQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMGFDAEIFQFKEHTKDIIEVMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKLAPK-KTNKYNDHVGESIKKWKHSFLISLIFGVPTMIVMMVFMYGFSHRMQVIHLKNGINVTVMVSNAPIXXXXXXXXXXXXXXXXX-----PVQFYGARYFYVQAYKSIKHGSANMDVLVVMATSVSYIYSFIVILVSMILRQDSSPQTFFETTPMLIVFLSLGRWLEHIAKGKTSEALSKLLSLQAFEATIIVNDN------QERKISXXXXXXXXXXXXXPGEKIPIDGRVVSGKSRCDESLITGESMSVEKIPGSDVIGGTLNISGMLIIRATLVGEDSALNQIVKLVEEAQTSKAPIQELADKVAGLFVPGVIICSMFTLLIWIAIGYTNPNLL----PGHSSINTDNTELIWKYAFQLAITVLSVACPCSLGLATPTAVMVGTGVGAINGILIKGGVPLEKMHQLDVIVFDKTGTITTGKPSVTNFVMCVENVTSQIRNCILLMLGAAESSSEHPIGKAILQYVRETCDINEMPQVVHSKSVSGFGLEC------SLKLQSDMFVPDSEIDNVLVKINDFQENNLTENLKETSVKWRKINEPVEVVLYLGNRNMMKENHISIPDKLDELMSRDEDNGRTVVLMAIDKVLLAMISIADQVKKEAALVVYTLEKMGVEVFLLTGDNHKTATAIAKEIGIRNVFAEVLPSHKVAKIQQIQNMSKYKRSWLFSCCSKPSKLTNVAMVGDGINDSPALAQADVGIAIGTGTDVAVEAADVVLIRNSLLDVIAAMKLSKDTVRRIRQNFVAATMYNLIGIPIAAGALMPIGVVFMPWMA 3000
            L  +  K KE ++  E       KC ++I GMTC+SCV  IE  +    G+ S L+ L+++  EV Y+P ++    IA+ I ++GF A + +  + +   +E++I+GMTC+SCV+ IES L + +GI+   VAL T K   K+DP++  PRDI+  IE +GF+A L  K ++  + DH  E I++WK SFLISL+F VP M  MM++M    H + + H  N       + ++ +      L  L +    S     PVQF G R+FY QAYK++KH SANMDVL+V+ATS+++ YS ++++V+MI +   +P TFF+T PML VF+SLGRWLE IAK KTSEALSKL+SLQA EAT++  +        E ++ V+LV++GD+VKV+PG K P+DGRV+ G S  DESLITGE+M V K PGS VI G++N +G L+IRAT VG D+ L+QIVKLVEEAQTSKAPIQ+ AD+++G FVP ++  S+ TLL WIAIG+ N  L+    PG+   +    E I ++AFQ +ITVL +ACPCSLGLATPTAVMVGTGVGA NGILIKGG PLE  H++  +VFDKTGTIT G P V    + VE      R+ +L ++G AE++SEHP+G AI ++ ++      +      ++V G G+ C      +L  + D    +++ + +LV+I+D + ++    L         +      VL +GNR  M+ N + I   +DE M+  E  GRT VL+A+D  L AM++IAD VK EA L V+TL  MG+EV L+TGDN KTA AIA ++GIR VFAEVLPSHKVAK++Q+Q   K                  VAMVGDG+NDSPALA ADVGIAIGTGTDVA+EAADVVLIRN LLDV+A++ LSK TV+RIR NFV A +YNL+GIPIAAG  MPIG+V  PWM 
Sbjct:  466 LSTIKEKEKELESDTEAGLNTHSKCFIQIGGMTCASCVANIERNLKNEHGIHSVLVALMASKAEVRYNPAVMDPLKIAECIRELGFTASVMENYDGSDGALELVIRGMTCASCVHKIESSLMKQKGIVYASVALATNKAHVKYDPEVTGPRDIIRLIENLGFEALLVKKDRSGSHLDHSIE-IQQWKKSFLISLVFCVPVM-GMMIYMMVVDHMIVMSHHHNATREDRQMYHSHMFLERQLLPGLSIMNLLSFLFCVPVQFIGGRHFYAQAYKALKHWSANMDVLIVLATSIAFTYSLVILMVAMIEKAKVNPITFFDTPPMLFVFISLGRWLEQIAKSKTSEALSKLMSLQATEATVVTLNGDTMAVLSEEQVDVELVQRGDIVKVVPGGKFPVDGRVIEGHSMADESLITGEAMPVTKKPGSTVIAGSINQNGSLLIRATHVGTDTTLSQIVKLVEEAQTSKAPIQQFADRISGYFVPFIVAVSVLTLLAWIAIGFVNFRLVEMYFPGYDK-SVSQAEAIIRFAFQASITVLCIACPCSLGLATPTAVMVGTGVGAQNGILIKGGEPLEMAHRIQSVVFDKTGTITYGAPKVVQVKILVEG-NRMPRSKLLAIVGTAENNSEHPLGAAITRFCKQELGTEMLGTCTDFQAVPGCGIRCHVSNTENLVKREDSDGEENQRNAILVQISDPRASSNAHPLIMDPEPLTLVQSASYTVL-IGNREWMRRNALHIRPDVDEAMTEHERRGRTAVLVAVDGELCAMVAIADTVKPEAELAVHTLTSMGLEVVLMTGDNSKTARAIAAQVGIRKVFAEVLPSHKVAKVEQLQQAGK-----------------RVAMVGDGVNDSPALAMADVGIAIGTGTDVAIEAADVVLIRNDLLDVVASIDLSKKTVKRIRINFVFALIYNLVGIPIAAGVFMPIGLVLQPWMG 1387

HSP 2 Score: 90.8929 bits (224), Expect = 5.948e-18
Identity = 48/158 (30.38%), Postives = 86/158 (54.43%), Query Frame = 1

Query:  319 IQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDM----------GFDAEI----------FQFKEHTKDIIEVMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKL 732
            + GM C+SCV  I++ + K++GV S  ++L      + ++P ++  + +   I  +          G DA +             ++     +++ I+GMTC+SCV +IE  ++Q +G+ S +V+L   +G F+FDP + +P ++  AIEEMGFDA L
Sbjct:  285 VSGMHCNSCVVNIQDNIGKVRGVSSVQVSLEKRQAVIQHNPSIVTVAALQRAIEALPPGKFKTQLDGQDATLPSSLSELSLLQLSEQPLASTVQIHIEGMTCNSCVQSIEGTISQRKGVRSAQVSLANHQGTFEFDPLLTAPEELRAAIEEMGFDAFL 442

HSP 3 Score: 68.1662 bits (165), Expect = 5.114e-11
Identity = 39/133 (29.32%), Postives = 68/133 (51.13%), Query Frame = 1

Query:  313 MRIQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMGFDAEIFQFKEHTKDIIEVMIQGMT-CSS-CVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAI 705
            + ++GMTC SCV TIE Q+  L GV    ++L      V +DP       +AD I DMGF++++      T    E  +   T CS+       ++LAQ++G++  + ++  +     F P ++SP  + +A+
Sbjct:   13 LTVEGMTCGSCVQTIEQQIGGLSGVIHIEVSLEQKNATVIFDPASHSPESLADAIEDMGFESDVTNASPTTPVQTETRVYPTTGCSAEAQRQAHTQLAQLKGVVETQESIEGKGLAVTFIPTVVSPERVREAV 145

HSP 4 Score: 62.3882 bits (150), Expect = 3.253e-9
Identity = 25/64 (39.06%), Postives = 42/64 (65.62%), Query Frame = 1

Query:  535 IEVMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDA 726
            + + ++GMTC SCV TIE ++  + G++ ++V+L  +     FDP   SP  + DAIE+MGF++
Sbjct:   11 VTLTVEGMTCGSCVQTIEQQIGGLSGVIHIEVSLEQKNATVIFDPASHSPESLADAIEDMGFES 74

HSP 5 Score: 55.4546 bits (132), Expect = 3.670e-7
Identity = 42/179 (23.46%), Postives = 85/179 (47.49%), Query Frame = 1

Query:  226 TLCEAIENLGFLINKNKETDNTKELFKCHMRIQGMT-CSS-CVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMGFDAEIFQFKEHTK-----DIIEVMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKLAPK 741
            +L +AIE++GF  +    +  T    +   R+   T CS+        Q+ +LKGV     ++      VT+ P ++    + + ++ +         +   +     +++++ I GM C SC  TIE K+ +++G+  +KV L +++    + P +I+  DI++ I   GF A +  K
Sbjct:   62 SLADAIEDMGFESDVTNASPTTP--VQTETRVYPTTGCSAEAQRQAHTQLAQLKGVVETQESIEGKGLAVTFIPTVVSPERVREAVSCLVPQPASTSERSTGRGSGNVEVVKMRIDGMVCLSCTTTIEGKIGKLKGVEKIKVGLESQEATVLYLPYLITVEDIVNQIGVAGFKASVKSK 238

[Close]

BLAST of Copper-transporting ATPase 1 vs. Ensembl Cavefish
Match: atp7b (ATPase copper transporting beta [Source:ZFIN;Acc:ZDB-GENE-061220-5])

HSP 1 Score: 536.569 bits (1381), Expect = 1.060e-170
Identity = 305/597 (51.09%), Postives = 403/597 (67.50%), Query Frame = 1

Query: 1228 KGKTSEALSKLLSLQAFEATIIV--NDNQ---ERKISXXXXXXXXXXXXXPGEKIPIDGRVVSGKSRCDESLITGESMSVEKIPGSDVIGGTLNISGMLIIRATLVGEDSALNQIVKLVEEAQTSKAPIQELADKVAGLFVPGVIICSMFTLLIWIAIGYTNPNLLPGHSSINTDNTELIWKYAFQLAITVLSVACPCSLGLATPTAVMVGTGVGAINGILIKGGVPLEKMHQLDVIVFDKTGTITTGKPSVTNFVMCVENVTSQIRNCILLMLGAAESSSEHPIGKAILQYVRETCDINEMPQVVHS-KSVSGFGLECSLKLQSDMFVPDSEIDNVLVKINDFQENNLTENLKETSVKWRKINEPVEVVLYLGNRNMMKENHISIPDKLDELMSRDEDNGRTVVLMAIDKVLLAMISIADQVKKEAALVVYTLEKMGVEVFLLTGDNHKTATAIAKEIGIRNVFAEVLPSHKVAKIQQIQNMSKYKRSWLFSCCSKPSKLTNVAMVGDGINDSPALAQADVGIAIGTGTDVAVEAADVVLIRNSLLDVIAAMKLSKDTVRRIRQNFVAATMYNLIGIPIAAGALMPIGVVFMPWMA 3000
            + KTSEAL+KL+SLQA +ATI+   +DN    E ++SV LV++GD+VKV PG K P+DG+V+ G S  DESLITGE M V K PGS VI G++N  G L++ AT VG D+ L+QIV+LVEEAQTSKAPIQ+LADK++G FVP +++ S+ TL      GY            N   T++I ++AFQ +ITVLS+ACPCSLGLATPTAVMVGTGVGA NGILIKGG PLE  H++  ++FDKTGTIT G P VT  ++  +     +R  +L ++G AE+SSEHP+G    Q ++     +E+    H  ++V G G+ C                    K+++ +E  L +N  E          P    + +GNR  M+ N I +   +DE MS  E  G+T +L+AID VL AM++IAD VK+E+AL V+TL +MG++V ++TGDN +TA AIA ++GIR VFAEVLPSHKVAK+Q++Q                 +K   VAMVGDG+NDSPALA+AD+GIAIGTGTDVA+EAADVVLIRN LLDV+A+++LSK TV+RIR NF+ A +YNL+GIPIAAG  MP+G+V  PWM 
Sbjct:  647 QSKTSEALAKLMSLQAVDATIVTLGHDNSIISEEQVSVQLVQRGDVVKVAPGGKFPVDGKVIEGSSMADESLITGEPMPVRKKPGSCVIAGSINAHGALLVEATHVGADTTLSQIVRLVEEAQTSKAPIQQLADKLSGYFVPFIVVVSVATL------GYDT----------NIPRTDVIVRFAFQASITVLSIACPCSLGLATPTAVMVGTGVGAQNGILIKGGEPLEMAHKIKAVMFDKTGTITNGVPRVTRVLVLWDQARLPLRK-VLAVVGTAEASSEHPLGNGSCQTLQ-----SELLGHCHDFQAVPGCGISC--------------------KVSNIEE--LLQNSSEA-------EGPPTYSVLIGNRQWMQRNAIQVTADVDEAMSSHETKGQTAILVAIDGVLCAMLAIADTVKEESALAVHTLSRMGIDVLMITGDNRRTAKAIATQVGIRKVFAEVLPSHKVAKVQELQ-----------------AKGLKVAMVGDGVNDSPALARADLGIAIGTGTDVAIEAADVVLIRNDLLDVVASIELSKKTVQRIRINFMFALIYNLLGIPIAAGVFMPVGLVLQPWMG 1175

HSP 2 Score: 157.147 bits (396), Expect = 2.414e-38
Identity = 78/188 (41.49%), Postives = 117/188 (62.23%), Query Frame = 1

Query:  304 KCHMRIQGMTCSSCVHTIENQVLKLKGV--KSALINLLSTIGEVTYDPDLIMASDIADTINDMGFDAEIFQFKEHTKDIIEVMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKLAPKKTNKYNDHVG--ESIKKWKHSFLISLIFGVPTMIVMMVFM 855
            KC + + GMTC+SCV  IE  +LK KGV  KS L+ L++   E+ YDP+ +  + I   I+ +GF A + +       ++++ + GMTC+SCV+ IESKL + +GIL   V+L T K   KFDP ++  RDI+  +E +GF A L      + N+ +G  E I++WKHSFLISL+ G+P M +M+  M
Sbjct:  422 KCFVCVTGMTCASCVSNIERTLLKHKGVWIKSVLVALMAGKAEIKYDPEDLDPAQIVKLISGLGFGASLVEEGAINDGVLDLSVTGMTCASCVHNIESKLCRSKGILEATVSLATSKAHVKFDPDVVGVRDIIRIVEGLGFGASLIKSDDLRKNNDLGHQEEIRQWKHSFLISLVCGIPVMGLMIYMM 609

HSP 3 Score: 85.8853 bits (211), Expect = 1.792e-16
Identity = 59/199 (29.65%), Postives = 92/199 (46.23%), Query Frame = 1

Query:  274 KETDNTKELFKCHMRIQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMGFDAEIFQFK--EHT----------------------------------KDIIE--------VMIQGMTCSSCVYTIESKLAQMQGIL--SVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKL 732
            +  ++ + L K  + I+GMTC+SCV +IE  + +  GV S  + L    G +T+D  L  ++++ D I DMGF+A + Q +   HT                                  + I+         V + GMTC+SCV  IE  L + +G+   SV VAL   K + K+DP+ + P  I+  I  +GF A L
Sbjct:  292 RSQNSVESLQKVTIGIKGMTCNSCVQSIEGLISQKHGVHSITVYLKEEKGVITFDSSLTTSTELRDAIEDMGFEAFLKQGRVCSHTFFSYSIFCLLILSVYFKKEMDRLNSKVDSNLPWQRSILHLAPFQKCFVCVTGMTCASCVSNIERTLLKHKGVWIKSVLVALMAGKAEIKYDPEDLDPAQIVKLISGLGFGASL 490

HSP 4 Score: 83.9593 bits (206), Expect = 8.544e-16
Identity = 51/168 (30.36%), Postives = 83/168 (49.40%), Query Frame = 1

Query:  286 NTKELFKCHMRIQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDM---GFDAEIFQ----FKEHTKDIIE------------VMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKL 732
            +T +  +  + ++GM C SCV  I   +  + GV+S L+ L S   ++ YDP L+    +   +  +    F   + +     K  T   I             + I+GMTC+SCV +IE  ++Q  G+ S+ V L  EKG   FD  + +  ++ DAIE+MGF+A L
Sbjct:  201 HTPDWLEVRLGVEGMHCGSCVKNITENLSGMLGVQSVLVYLESKTLDLKYDPSLVTLDTVKGVLESLPPGNFKVTLPESGSFHKPRTNGSIRSQNSVESLQKVTIGIKGMTCNSCVQSIEGLISQKHGVHSITVYLKEEKGVITFDSSLTTSTELRDAIEDMGFEAFL 368

HSP 5 Score: 75.8702 bits (185), Expect = 2.032e-13
Identity = 44/173 (25.43%), Postives = 84/173 (48.55%), Query Frame = 1

Query:  286 NTKELFKCHMRIQGMTCSSCVHTIENQVLKLKGVKSALI-NLLSTIGEVTYDPDLIMASDIADTINDMGF------DAEIFQ--FKEHTKDIIEVMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDA----KLAPKKTNKYNDH 765
            N+    +  + I G T   CV  +++ +  L GV +  +    S +  + + P  +   +I   I  MG+      +A + Q       + ++ + ++GMTC SCV TIE ++  +QG+L ++V+L+ ++    F+ + + P ++   IEEMGF+A     L P    +   H
Sbjct:   29 NSGHPSRLSLLISGPTSPDCVQGLQSWLSALSGVTAVSVPQSGSGLAWIDFHPSTVTTREILQEIQGMGYGVNEVSNAGVSQPALPRLEESLVRISVEGMTCHSCVRTIEGRIGALQGVLGIQVSLSEKEAVIWFNNETVKPDELRKHIEEMGFEAFVKDPLVPHLATQAGPH 201

[Close]

BLAST of Copper-transporting ATPase 1 vs. Ensembl Cavefish
Match: atp2c1 (ATPase secretory pathway Ca2+ transporting 1 [Source:ZFIN;Acc:ZDB-GENE-060503-615])

HSP 1 Score: 80.8777 bits (198), Expect = 5.968e-15
Identity = 59/168 (35.12%), Postives = 90/168 (53.57%), Query Frame = 1

Query: 2446 LLAMISIADQVKKEAALVVYTLEKMGVEVFLLTGDNHKTATAIAKEIGIRNVFAEVLPSHKVAKIQQIQNMSK-YKRSWLFSCCSKPSKL----------TNVAMVGDGINDSPALAQADVGIAIG-TGTDVAVEAADVVLIRNSLLDVIAAMKLSKDTVRRIRQNFV 2913
             L ++ I D  +      V TL   GV V ++TGD+ +TA AIA  +G+    ++ L   +V  +  IQ +S+   R  +F   S   KL            VAM GDG+ND+ AL  AD+G+A+G TGTDV  EAAD++L+ +    +++A++  K     I+ NFV
Sbjct:  516 FLGLVGIIDPPRAGVKDAVSTLISSGVAVKMITGDSQETAVAIASRLGLYTKGSQCLSGEEV-DVMDIQQLSQIVSRIVVFYRASPRHKLKIVKSLQNIGAVVAMTGDGVNDAVALKAADIGVAMGQTGTDVCKEAADMILVDDDFQTILSAIEEGKGIYNNIK-NFV 681

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BLAST of Copper-transporting ATPase 1 vs. Ensembl Cavefish
Match: atp2a1l (sarcoplasmic/endoplasmic reticulum calcium ATPase 1 [Source:NCBI gene;Acc:103039228])

HSP 1 Score: 79.337 bits (194), Expect = 1.684e-14
Identity = 50/172 (29.07%), Postives = 90/172 (52.33%), Query Frame = 1

Query: 2437 DKVLLAMISIADQVKKEAALVVYTLEKMGVEVFLLTGDNHKTATAIAKEIGIRNVFAEVLPSHKVAKIQQIQNMSKYKRSWLFS--CC------SKPSKLTN--------VAMVGDGINDSPALAQADVGIAIGTGTDVAVEAADVVLIRNSLLDVIAAMKLSKDTVRRIRQ 2904
            D   +  + + D  +KE    +      G+ V ++TGDN  TA AI + IGI N   +V  + +    ++  ++ + ++S   +  CC      S  SK+           AM GDG+ND+PAL +A++GIA+G+GT VA  A+++VL  ++   ++AA++  +     ++Q
Sbjct:  587 DLTFVGCVGMLDPPRKEVTGSIELCRAAGIRVIMITGDNKGTAVAICRRIGIFNEDEDV--TGRAYTGREFDDLPRTEQSEAVTRACCFARVEPSHKSKIVEFLQGYDEITAMTGDGVNDAPALKKAEIGIAMGSGTAVAKSASEMVLADDNFSSIVAAVEEGRAIYNNMKQ 756

[Close]

BLAST of Copper-transporting ATPase 1 vs. Ensembl Cavefish
Match: atp2a1l (sarcoplasmic/endoplasmic reticulum calcium ATPase 1 [Source:NCBI gene;Acc:103039228])

HSP 1 Score: 79.337 bits (194), Expect = 1.694e-14
Identity = 50/172 (29.07%), Postives = 90/172 (52.33%), Query Frame = 1

Query: 2437 DKVLLAMISIADQVKKEAALVVYTLEKMGVEVFLLTGDNHKTATAIAKEIGIRNVFAEVLPSHKVAKIQQIQNMSKYKRSWLFS--CC------SKPSKLTN--------VAMVGDGINDSPALAQADVGIAIGTGTDVAVEAADVVLIRNSLLDVIAAMKLSKDTVRRIRQ 2904
            D   +  + + D  +KE    +      G+ V ++TGDN  TA AI + IGI N   +V  + +    ++  ++ + ++S   +  CC      S  SK+           AM GDG+ND+PAL +A++GIA+G+GT VA  A+++VL  ++   ++AA++  +     ++Q
Sbjct:  581 DLTFVGCVGMLDPPRKEVTGSIELCRAAGIRVIMITGDNKGTAVAICRRIGIFNEDEDV--TGRAYTGREFDDLPRTEQSEAVTRACCFARVEPSHKSKIVEFLQGYDEITAMTGDGVNDAPALKKAEIGIAMGSGTAVAKSASEMVLADDNFSSIVAAVEEGRAIYNNMKQ 750

[Close]

BLAST of Copper-transporting ATPase 1 vs. Ensembl Sea Lamprey
Match: atp7b (ATPase copper transporting beta [Source:ZFIN;Acc:ZDB-GENE-061220-5])

HSP 1 Score: 636.336 bits (1640), Expect = 0.000e+0
Identity = 350/782 (44.76%), Postives = 504/782 (64.45%), Query Frame = 1

Query:  706 EEMGFDAKLAPK--KTNKYNDHVGESIKKWKHSFLISLIFGVPTMIVMMVFMYGFSHRMQVIHLKN-----GINVTVMVSNAPIXXXXXXXXXXXXXXXXXPVQFYGARYFYVQAYKSIKHGSANMDVLVVMATSVSYIYSFIVILVSMILRQDSSPQTFFETTPMLIVFLSLGRWLEHIAKGKTSEALSKLLSLQAFEATIIV--NDN---QERKISXXXXXXXXXXXXXPGEKIPIDGRVVSGKSRCDESLITGESMSVEKIPGSDVIGGTLNISGMLIIRATLVGEDSALNQIVKLVEEAQTSKAPIQELADKVAGLFVPGVIICSMFTLLIWIAIGYTN--------PNLLPGHSSINTDNTELIWKYAFQLAITVLSVACPCSLGLATPTAVMVGTGVGAINGILIKGGVPLEKMHQLDVIVFDKTGTITTGKPSVTNFVMCVENVTSQIRNCILLMLGAAESSSEHPIGKAILQYVRETCDINEMPQVVHSKSVSGFGLECSLKLQSDMFVPDSEIDNVLVKINDFQENNLTENLKETSVKWRKI--------------NEPVEVVLYLGNRNMMKENHISIPDKLDELMSRDEDNGRTVVLMAIDKVLLAMISIADQVKKEAALVVYTLEKMGVEVFLLTGDNHKTATAIAKEIGIRNVFAEVLPSHKVAKIQQIQNMSKYKRSWLFSCCSKPSKLTNVAMVGDGINDSPALAQADVGIAIGTGTDVAVEAADVVLIRNSLLDVIAAMKLSKDTVRRIRQNFVAATMYNLIGIPI 2949
            + MG+ A L  +  +   + +H  E I++W+++FL++L+FG+P M  +MV+M     + +  +L N     G++   +V  A                  +PVQF G R+FY +AYKS+K+ +ANMDVL+V+ATS++Y+YS +++LV+M  R   SP TFF+T PML VF++LGRWLEH+AKGKTSEAL+KL+SLQA EAT++    DN    E ++ V+L+++GD ++V+PG + P+DGRV++G S  DES+ITGE M V K PGS VI G++N  G L++ AT VG D+ L QIV+LVEEAQTSKAPIQ+LAD+++G FVP V++ S  TL+ WI +G+ +        P+  P     +  + E++ ++AFQ AITVLS+ACPC+LGLATPTAVMVGTGVGA NGILIKGG PLE  H++  +VFDKTGT+T G P V  F +         R  +  ++G AE+SSEHP+G AI ++ ++      +      ++V GFG+ C +          S +D  L  +++ +EN   +N   ++   R                +E     + +GNR  M  + + +   +   M++ E+ G T VL+A+D  L  M++IAD VK+EAALVV TL  MG+ V LLTGDN +TA AIA ++G+R  +AEVLP+ KV +++++Q                      VAMVGDG+NDSPALAQADVGIAIG+GTDVA+ AAD+VLIR++LLDV+++++LSK TV RIR NF+ A +YNL+G+PI
Sbjct:    1 QRMGYTAALVKQECRGTSHLEHTDE-IRQWRNAFLLNLLFGIPVM-ALMVYMIVMDSQKKHNYLMNHMVLPGLSTINLVFFA----------------LCTPVQFVGGRHFYARAYKSVKYRAANMDVLIVLATSIAYVYSVVILLVAMAERAPRSPLTFFDTPPMLFVFITLGRWLEHLAKGKTSEALAKLMSLQAAEATLVTLGPDNSLVSEEQVEVELLQRGDALRVVPGARFPVDGRVIAGTSMADESIITGEVMPVSKGPGSLVIAGSINQMGSLLVEATHVGADTTLAQIVRLVEEAQTSKAPIQQLADRLSGYFVPTVVLLSTLTLVTWIVVGFADFAVVQKYFPDFDP-----SLPHGEVVLRFAFQAAITVLSIACPCALGLATPTAVMVGTGVGAQNGILIKGGEPLEMAHKIKAVVFDKTGTLTHGMPRVLRFALFGNRARVSPRR-LTAIVGTAEASSEHPLGVAITKHCKQELSTERLGSCQAFQAVPGFGISCEV----------SNVDAALNAVDEDEENE--KNASPSAPANRSAPHIIMDGDESTATRHELQRYAVLIGNREWMGRSGVEVAPAVHAAMAQHEEQGHTAVLVAVDGQLCGMLAIADAVKEEAALVVRTLTAMGLHVILLTGDNRRTARAIAAQVGVRTAYAEVLPADKVREVERLQRQG-----------------LRVAMVGDGVNDSPALAQADVGIAIGSGTDVAIAAADIVLIRSNLLDVVSSIELSKKTVLRIRINFIFALVYNLLGLPI 729

[Close]

BLAST of Copper-transporting ATPase 1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002230.1 (pep scaffold:Pmarinus_7.0:GL493059:69:4752:-1 gene:ENSPMAG00000002031.1 transcript:ENSPMAT00000002230.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 207.994 bits (528), Expect = 2.489e-62
Identity = 107/171 (62.57%), Postives = 130/171 (76.02%), Query Frame = 1

Query: 2446 LLAMISIADQVKKEAALVVYTLEKMGVEVFLLTGDNHKTATAIAKEIGIRNVFAEVLPSHKVAKIQQIQNMSKYKRSWLFSCCSKPSKLTNVAMVGDGINDSPALAQADVGIAIGTGTDVAVEAADVVLIRNSLLDVIAAMKLSKDTVRRIRQNFVAATMYNLIGIPIAAG 2958
            L  M++IAD VK EAAL V TL  MG++V L+TGDN KTA AIA ++GIR VFAEVLPSHKVAK++Q+Q   +                  VAMVGDG+NDSPALA++DVGIA+GTGTDVA+EAAD+VLIRN LLDV+A++ LSK TVRRI  NFV A +YN++GIPIAAG
Sbjct:    6 LCGMLAIADTVKPEAALAVRTLADMGLQVVLMTGDNRKTAQAIAAQVGIRRVFAEVLPSHKVAKVEQLQESGQ-----------------TVAMVGDGVNDSPALARSDVGIALGTGTDVAIEAADIVLIRNDLLDVVASIHLSKKTVRRIHINFVFALIYNVVGIPIAAG 159

[Close]

BLAST of Copper-transporting ATPase 1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000010051.1 (pep scaffold:Pmarinus_7.0:GL484878:2955:5956:-1 gene:ENSPMAG00000009092.1 transcript:ENSPMAT00000010051.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 72.7886 bits (177), Expect = 1.779e-13
Identity = 44/167 (26.35%), Postives = 74/167 (44.31%), Query Frame = 1

Query:  319 IQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMGFDAEIFQFKEHTKDI-----------------------------IEVMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKL 732
            ++GM C SCV  IE+ V +L  V S  ++L  +  ++ Y+P L+  +D+   I  +        F   + D+                             + + + GMTC+SCV  +E  LA+  G+ SV V+L        +D  + SP  +  A+E+MG+ A L
Sbjct:  240 VEGMHCKSCVDNIESHVGELAAVYSIEVSLSESKADIRYNPTLLGPADLKQAIESLPPGNLSVSFGLRSTDLPSPNVYQSLLSRCAKGAVEEPVPRADNPTVVLRVTGMTCASCVQNVEGGLAKRAGVRSVSVSLGDGTATVSYDRGVTSPEILQGAVEDMGYGATL 406

HSP 2 Score: 70.4774 bits (171), Expect = 9.758e-13
Identity = 45/185 (24.32%), Postives = 88/185 (47.57%), Query Frame = 1

Query:  229 LCEAIENLGF--LINKNKETDNTKELFKCHMRIQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMGFDAEIFQF---KEHTKDI------------------IEVMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEM 714
            +C+ IE+ G+   +   +       L    + ++GM   +C   +E+ + KL GV+    +L S    + Y   LI AS++   I  +GF A + +    +E ++ +                  I + ++GM C SCV  IES + ++  + S++V+L+  K   +++P ++ P D+  AIE +
Sbjct:  114 ICQKIEDFGYRATLQAGRRQPGLATLV---VTVEGMKRQTCARRVESALAKLPGVEHVEASLASREVRIGYKSHLINASELRRQIEALGFAALLPKSPLKREKSRALPADPQSSAPPSEAIESATITLGVEGMHCKSCVDNIESHVGELAAVYSIEVSLSESKADIRYNPTLLGPADLKQAIESL 295

HSP 3 Score: 56.225 bits (134), Expect = 3.437e-8
Identity = 36/135 (26.67%), Postives = 55/135 (40.74%), Query Frame = 1

Query:  313 MRIQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMGFDA-----------------------------------EIFQFKEHTKDIIEVMIQGMTCSSCVYTIESKLAQMQG 612
            +R+ GMTC+SCV  +E  + K  GV+S  ++L      V+YD  +     +   + DMG+ A                                   E    +E  K ++ V   GMTC+SCV  IE+ L +  G
Sbjct:  343 LRVTGMTCASCVQNVEGGLAKRAGVRSVSVSLGDGTATVSYDRGVTSPEILQGAVEDMGYGATLTGNIPLSLSPVTFPPSLTVNLDLYVELPPKPSGEREDAREPEKCLLRVT--GMTCASCVANIENNLKKKDG 475

HSP 4 Score: 51.6026 bits (122), Expect = 9.271e-7
Identity = 46/190 (24.21%), Postives = 89/190 (46.84%), Query Frame = 1

Query:  226 TLCEAIENLGFLINKNKETDNTK---ELFKCHMRIQGMTCSSCVH--TIENQVLKLKGVKSA-LINLLSTIGE-------VTYDPDLIMASDIADTINDMGFDAEIFQFKEHTK-DIIEVMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKLAPKKTNK 753
            +L EA+E  GF  + +   D ++   +     + + G T S+ +   ++ +    L+GV +  ++   S   E       VT+ P+L  A+ I   I D G+ A +   +       + V ++GM   +C   +ES LA++ G+  V+ +L + + +  +   +I+  ++   IE +GF A L PK   K
Sbjct:   22 SLLEAVERAGFEASLDLGGDGSRFPADTESVEILVTGATPSAELRGRSLADLAASLRGVTATDVVRSPSEEAEDARRKMNVTFLPELTGANVICQKIEDFGYRATLQAGRRQPGLATLVVTVEGMKRQTCARRVESALAKLPGVEHVEASLASREVRIGYKSHLINASELRRQIEALGF-AALLPKSPLK 210

[Close]

BLAST of Copper-transporting ATPase 1 vs. Ensembl Sea Lamprey
Match: atp2c1 (ATPase secretory pathway Ca2+ transporting 1 [Source:ZFIN;Acc:ZDB-GENE-060503-615])

HSP 1 Score: 68.1662 bits (165), Expect = 5.835e-12
Identity = 54/171 (31.58%), Postives = 89/171 (52.05%), Query Frame = 1

Query: 2446 LLAMISIADQ----VKKEAALVVYTLEKMGVEVFLLTGDNHKTATAIAKEIGIRNVFAEVLPSHKVAKIQQIQNMSKYKRSWLFSCCSKPSKLT----------NVAMVGDGINDSPALAQADVGIAIG-TGTDVAVEAADVVLIRNSLLDVIAAMKLSKDTVRRIRQNFV 2913
             L ++ I D     V+K  A++V +    GV V ++TGD+ +TA AIA  +G+ +       S +   ++  Q     ++  +F   S   KL            V M GDG+ND+ AL  AD+G+A+G +GTDV  EAAD++L+ +    +++A++  K     I+ NFV
Sbjct:   75 FLGLVGIIDPPRPGVRKSVAILVSS----GVSVKMVTGDSMETAVAIANRLGLSSNGGGAAISGEEDLMETTQLSQIIRKVSVFYRASPRHKLKIVKALQKNGEVVGMTGDGVNDAVALRAADIGVAMGRSGTDVCKEAADMILVDDDFYTIMSAIEEGKGIFYNIK-NFV 240

[Close]

BLAST of Copper-transporting ATPase 1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000010373.1 (pep scaffold:Pmarinus_7.0:GL481096:3909:20014:1 gene:ENSPMAG00000009373.1 transcript:ENSPMAT00000010373.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 68.5514 bits (166), Expect = 7.456e-12
Identity = 48/180 (26.67%), Postives = 80/180 (44.44%), Query Frame = 1

Query: 2458 ISIADQVKKEAALVVYTLEKMGVEVFLLTGDNHKTATAIAKEIGI-------------------------------RNVFAEVLPSHKVAKIQQIQNMSKYKRSWLFSCCSKPSKLTNVAMVGDGINDSPALAQADVGIAIGTGTDVAVEAADVVLIRNSLLDVIAAMKLSKDTVRRIRQ 2904
            + + D  +KE +  +    + G+ V    GDN  TA AI + IGI                                  FA V PSHK   ++ +Q+  +                   AM GDG+ND+PAL +A++GIA+G+GT VA  A+++VL  ++   ++AA++  +     ++Q
Sbjct:  447 VGMLDPPRKEVSSSIILCREAGIRVI---GDNKGTAVAICRRIGIFGEDEDVKDKAYTGREFDDLPLEEQRLACQRARCFARVEPSHKSKIVEFLQSCDEI-----------------TAMTGDGVNDAPALKKAEIGIAMGSGTAVAKSASEMVLADDNFSSIVAAVEEGRAIYNNMKQ 606

[Close]

BLAST of Copper-transporting ATPase 1 vs. Ensembl Yeast
Match: CCC2 (Cu(+2)-transporting P-type ATPase; required for export of copper from the cytosol into an extracytosolic compartment; similar to human proteins involved in Menkes and Wilsons diseases; protein abundance increases in response to DNA replication stress; affects TBSV model (+)RNA virus replication by regulating copper metabolism; human homologs ATP7A and ATP7B both complement yeast null mutant [Source:SGD;Acc:S000002678])

HSP 1 Score: 426.017 bits (1094), Expect = 5.598e-132
Identity = 318/981 (32.42%), Postives = 514/981 (52.40%), Query Frame = 1

Query:  202 HNDNCTYLTLCEAIENLGFLINKNKETD----NTKELFKCHMRIQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMGFDAEIFQFKEHTKDIIE-VMIQGMTC-----SSCVYTIESKLAQMQ---GILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKLAPKKTNKYNDHV---GESIKKWKHSFLISLIFGV-------------PTMIVMMVFMYGFSHRMQVIHLKNGINVTVMVSNAPIXXXXXXXXXXXXXXXXXPVQFYGARYFYVQAYKSIKHGSANMDVLVVMATSVSYIYSFIVILVSMILRQDSS--PQTFFETTPMLIVFLSLGRWLEHIAKGKTSEALSKLLSLQAFEATII--VNDNQERKISXXXXXXXXXXXXXPGEKIPIDGRVVSGKSRCDESLITGESMSVEKIPGSDVIGGTLNISGMLIIRATLVGEDSALNQIVKLVEEAQTSKAPIQELADKVAGLFVPGVIICSMFTLLIWIAIGYTNPNLLPGHSSINTDNTELIWKYAFQLAITVLSVACPCSLGLATPTAVMVGTGVGAINGILIKGGVPLEKMHQLDVIVFDKTGTITTGKPSVTNFVMCVENVTSQIRNCILLMLGAAESSSEHPIGKAILQYVRETCDINEMPQVVHSKSVSGFGLECSLKLQSDMFVPDSEIDNVLVK--INDFQENNLTENLKETSVKWRKINEPVEVVLYLGNRNMMKENHISIPDKLDELMSRDEDNGRTVVLMAIDKVLLAMISIADQVKKEAALVVYTLEKMGVEVFLLTGDNHKTATAIAKEIGI--RNVFAEVLPSHKVAKIQQIQNMSKYKRSWLFSCCSKPSKLTNVAMVGDGINDSPALAQADVGIAIGTGTDVAVEAADVVLI------RNSLLDVIAAMKLSKDTVRRIRQNFVAATMYNLIGIPIAAGALMPIGVVFMPWMASVAMA 3015
            +++  T  ++ E IE+ GF     ++++    +TKE     + +QGMTC SCV T+  QV  ++GV+S +++L++    V Y+P         + I D GFD+ I        D+ E  +I  +T      S  + +  S+  Q     G+ S++++        K+    +  RD+L  +E  G+   +     N     +    + I+ WK + + S +  +             PT++   +F Y  +  ++ +  ++ + V +                      +S +QF    YFY  A+ S+KHGS  MD LV ++T+ +Y +S   ++ +M     +   P+  F+T+ M+I ++S+G++LE +AK +TS ALSKL+ L     +II  V  N+ ++I ++L++  D+V++ PG KIP DG +  G+S  DESL+TGES+ V K  G  VI G++N  G    R T VGE++ L  I+K+++EAQ SKAPIQ  AD +A +FVPG++I ++ T  IW  I   + N  P   + NT           Q A +V+ VACPC+LGLATPTA+MVGTGVGA NG+LIKGG  LEK + +   VFDKTGT+TTG   V  F+     V +   + +L  + A ES S+HP+ KAI++Y    CD                GL C+  L + +     E + VL K  ++  Q N  T +                  + +GN  ++ E+ +    K    ++ + D G TV  ++++  +  +  I D+VK ++   V  L++ G E +++TGDN+  A  +A+E+GI   NV+++V P+ K   +++IQ+     +               VA+VGDGIND+PALA +D+GIAI TGT++A+EAAD+V++       NSL  +  A+ +S  T +RI+ N   A  YN+  IPIA G L+P G+   P +A +AMA
Sbjct:   46 YDNEVTADSIKEIIEDCGFDCEILRDSEITAISTKEGL---LSVQGMTCGSCVSTVTKQVEGIEGVESVVVSLVTEECHVIYEPSKTTLETAREMIEDCGFDSNIIMDGNGNADMTEKTVILKVTKAFEDESPLILSSVSERFQFLLDLGVKSIEISDDMHTLTIKYCCNELGIRDLLRHLERTGYKFTVFSNLDNTTQLRLLSKEDEIRFWKKNSIKSTLLAIICMLLYMIVPMMWPTIVQDRIFPYKETSFVRGLFYRDILGVIL----------------------ASYIQFSVGFYFYKAAWASLKHGSGTMDTLVCVSTTCAYTFSVFSLVHNMFHPSSTGKLPRIVFDTSIMIISYISIGKYLETLAKSQTSTALSKLIQLTPSVCSIISDVERNETKEIPIELLQVNDIVEIKPGMKIPADGIITRGESEIDESLMTGESILVPKKTGFPVIAGSVNGPGHFYFRTTTVGEETKLANIIKVMKEAQLSKAPIQGYADYLASIFVPGILILAVLTFFIWCFILNISANP-PVAFTANTKADNFF--ICLQTATSVVIVACPCALGLATPTAIMVGTGVGAQNGVLIKGGEVLEKFNSITTFVFDKTGTLTTGFMVVKKFLKDSNWVGNVDEDEVLACIKATESISDHPVSKAIIRY----CD----------------GLNCNKALNAVVL----ESEYVLGKGIVSKCQVNGNTYD------------------ICIGNEALILEDAL----KKSGFINSNVDQGNTVSYVSVNGHVFGLFEINDEVKHDSYATVQYLQRNGYETYMITGDNNSAAKRVAREVGISFENVYSDVSPTGKCDLVKKIQDKEGNNK---------------VAVVGDGINDAPALALSDLGIAISTGTEIAIEAADIVILCGNDLNTNSLRGLANAIDISLKTFKRIKLNLFWALCYNIFMIPIAMGVLIPWGITLPPMLAGLAMA 937

HSP 2 Score: 93.2041 bits (230), Expect = 1.254e-19
Identity = 53/144 (36.81%), Postives = 85/144 (59.03%), Query Frame = 1

Query:  313 MRIQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMGFDAEIFQFKE----HTKDIIEVMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKL 732
            + + GMTCS+C +TI  Q+  LKGV    I+L++   +VTYD + + A  I + I D GFD EI +  E     TK+ + + +QGMTC SCV T+  ++  ++G+ SV V+L TE+    ++P   +     + IE+ GFD+ +
Sbjct:    6 LAVHGMTCSACTNTINTQLRALKGVTKCDISLVTNECQVTYDNE-VTADSIKEIIEDCGFDCEILRDSEITAISTKEGL-LSVQGMTCGSCVSTVTKQVEGIEGVESVVVSLVTEECHVIYEPSKTTLETAREMIEDCGFDSNI 147

[Close]

BLAST of Copper-transporting ATPase 1 vs. Ensembl Yeast
Match: PCA1 (Cadmium transporting P-type ATPase; may also have a role in copper and iron homeostasis; stabilized by Cd binding, which prevents ubiquitination; S288C and other lab strains contain a G970R mutation which eliminates Cd transport function [Source:SGD;Acc:S000000499])

HSP 1 Score: 266.159 bits (679), Expect = 8.978e-74
Identity = 203/666 (30.48%), Postives = 338/666 (50.75%), Query Frame = 1

Query:  991 VQFYGARYFYVQAYKSIKHGSA-NMDVLVVMATSVSYIYSFIVILVSMILRQDSSPQTFFETTPMLIVFLSLGRWLEHIAKGKTSEALSKLLSLQAFEATIIVNDNQERKISXXXXXXXXXXXXXPGEKIPIDGRVVSGKSRCDESLITGESMSVEKIPGSDVIGGTLNISGMLIIRATLVGEDSALNQIVKLVEEAQTSKAPIQELADKVAGLFVPGVIICSMFTLLIWIAIGYTNPNLLPGHSSINTDNTELIWKYAFQLAITVLSVACPCSLGLATPTAVMVGTGVGAINGILIKGGVPLEKMHQLDVIVFDKTGTITTGKPSVTNFVMCVENVTSQIRNCILLMLGAAESSSEHPIGKAILQYVRETCDINEMPQVVHSKSVSGFGLE----CSLKLQSDMFVPDSEIDNVLVKINDFQENNLTENLKETSVKWRKINEPVEVVLYLGNRNMMKENHISIPDKLDELMSRDEDNGRTVVLMAIDKVLLAMISIADQVKKEAALVVYTLEKMGVEVFLLTGDNHKTATAIAKEIGIR--NVFAEVLPSHKVAKIQQIQNMSKYKRSWLFSCCSKPSKLTNVAMVGDGINDSPALAQADVGIAIGTGTDVAVEAADVVLIRNSLLDVIAAMKLSKDTVRRIRQNFVAATMYNLIGIPIAAGALM 2967
            +QF  A  FY+ A KS+       MD+L+V++TS +YI+S +     ++ R  S+ Q FFET+ +L+  + +GR++  +A+ +  +++S + SLQA  A ++    +E +I++ L++ GD+ KVLP  +IP DG V+SG S  DE+LITGESM V K   S V+ G++N +G L ++ + +  ++ ++ I  +V+EA+ +K  IQ +ADK+A  FVP +I  ++ T  +WIA+G          + I           A   AITVL V+CPC +GLA P   ++ +GV A  G++ K    +E  H    +VFDKTGT+T GK +V +     E V     N   L+LG  E   +HP+  AI  Y++E         V ++K+V+G  +E      LKLQ                                + +W            LG+ N         PD    L     + G +V   +++  + A+ ++ D ++ +A   +  L + G+ + +L+GD+     ++A  +GI   N+ +   P+ K   I+ I               S  SK   V   GDG ND+  L QA +G+ I  G++VA  AADVV+++  L +++  + +S+  + R++ NF+ +  YNL  I +AAGA +
Sbjct:  601 IQFVIAGPFYLNALKSLIFSRLIEMDLLIVLSTSAAYIFSIVSFGYFVVGRPLSTEQ-FFETSSLLVTLIMVGRFVSELARHRAVKSIS-VRSLQASSAILVDKTGKETEINIRLLQYGDIFKVLPDSRIPTDGTVISGSSEVDEALITGESMPVPKKCQSIVVAGSVNGTGTLFVKLSKLPGNNTISTIATMVDEAKLTKPKIQNIADKIASYFVPTIIGITVVTFCVWIAVGIRVEKQSRSDAVIQ----------AIIYAITVLIVSCPCVIGLAVPIVFVIASGVAAKRGVIFKSAESIEVAHNTSHVVFDKTGTLTEGKLTVVH-----ETVRGDRHNSQSLLLGLTE-GIKHPVSMAIASYLKE--KGVSAQNVSNTKAVTGKRVEGTSYSGLKLQGG------------------------------NCRW------------LGHNND--------PDVRKAL-----EQGYSVFCFSVNGSVTAVYALEDSLRADAVSTINLLRQRGISLHILSGDDDGAVRSMAARLGIESSNIRSHATPAEKSEYIKDIVEGRNCDS-------SSQSKRPVVVFCGDGTNDAIGLTQATIGVHINEGSEVAKLAADVVMLKPKLNNILTMITVSQKAMFRVKLNFLWSFTYNLFAILLAAGAFV 1184

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BLAST of Copper-transporting ATPase 1 vs. Ensembl Yeast
Match: PMA1 (Plasma membrane P2-type H+-ATPase; pumps protons out of cell; major regulator of cytoplasmic pH and plasma membrane potential; long-lived protein asymmetrically distributed at plasma membrane between mother cells and buds; accumulates at high levels in mother cells during aging, buds emerge with very low levels of Pma1p, newborn cells have low levels of Pma1p; Hsp30p plays a role in Pma1p regulation; interactions with Std1p appear to propagate [GAR+] [Source:SGD;Acc:S000002976])

HSP 1 Score: 103.605 bits (257), Expect = 6.743e-23
Identity = 144/600 (24.00%), Postives = 255/600 (42.50%), Query Frame = 1

Query: 1210 WLEHIAKGKTSEALSKLLSLQAFEATIIVNDNQERKISXXXXXXXXXXXXXPGEKIPIDGRVVSGKS--RCDESLITGESMSVEKIPGSDVIGGTLNISGMLIIRATLVGEDSALNQIVKLVEEAQTSKAPIQELADKVAGLFVPGVIICSMFTLLIWIAIGYTNPNLLPGHSSINTDNTELIWKYAFQLAITVLSVACPCSLGLATPTAVMVGTGVGAINGILIKGGVPLEKMHQLDVIVFDKTGTITTGKPSVTNFVMCVENVTSQIRNCILLMLGAAESSSEHPIGKAILQYVRETCDINEMPQVVHSKSVSGFGLECSLKLQSDMFVPDSEIDNVLVKINDFQENNLTENLKETSVKWRKINEPVEVVLYLGNRNMMKEN-HISIPDKLDELMSRDEDNGRTVVLMAIDK-----VLLAMISIADQVKKEAALVVYTLEKMGVEVFLLTGDNHKTATAIAKEIGI-----------------------------RNVFAEVLPSHKVAKIQQIQNMSKYKRSWLFSCCSKPSKLTNVAMVGDGINDSPALAQADVGIAIGTGTDVAVEAADVVLIRNSLLDVIAAMKLSKDTVRRI 2898
            +++    G   + L K L+  A    +++ D Q  +I  + V  GD++++  G  IP DGR+V+     + D+S ITGES++V+K  G      +    G   +  T  G+++ + +   LV +A   +    E+ + + G+ +  ++I ++  LL+W A  Y             T+    I +Y   L IT++ V  P  L     T + VG    A    +++    +E +  ++++  DKTGT+T  K S+      VE V+         +  + +      I KA L+ +++       P+   + +          K +   F P    D V  K+    E+   E +    VK      P+ V+  +   + + E+ H +  +K+ EL SR    G   + +A  +      +L ++   D  + + A  V     +G+ V +LTGD    A    +++G+                              + FAEV P HK   ++ +QN     R +L            VAM GDG+ND+P+L +AD GIA+   TD A  AAD+V +   L  +I A+K S+    R+
Sbjct:  159 FVQEFQAGSIVDELKKTLANTA----VVIRDGQLVEIPANEVVPGDILQLEDGTVIPTDGRIVTEDCFLQIDQSAITGESLAVDKHYGDQTFSSSTVKRGEGFMVVTATGDNTFVGRAAALVNKAAGGQGHFTEVLNGI-GIILLVLVIATL--LLVWTACFY------------RTNGIVRILRYT--LGITIIGV--PVGLPAVVTTTMAVGAAYLAKKQAIVQKLSAIESLAGVEILCSDKTGTLTKNKLSLHE-PYTVEGVSPDDLMLTACLAASRKKKGLDAIDKAFLKSLKQ------YPKAKDALT----------KYKVLEFHP---FDPVSKKVTAVVESPEGERI--VCVK----GAPLFVLKTVEEDHPIPEDVHENYENKVAELASR----GFRALGVARKRGEGHWEILGVMPCMDPPRDDTAQTVSEARHLGLRVKMLTGDAVGIAKETCRQLGLGTNIYNAERLGLGGGGDMPGSELADFVENADGFAEVFPQHKYRVVEILQN-----RGYL------------VAMTGDGVNDAPSLKKADTGIAVEGATDAARSAADIVFLAPGLSAIIDALKTSRQIFHRM 688

[Close]

BLAST of Copper-transporting ATPase 1 vs. Ensembl Yeast
Match: PMA2 (Plasma membrane H+-ATPase; isoform of Pma1p, involved in pumping protons out of the cell; regulator of cytoplasmic pH and plasma membrane potential [Source:SGD;Acc:S000005957])

HSP 1 Score: 101.293 bits (251), Expect = 4.352e-22
Identity = 144/610 (23.61%), Postives = 261/610 (42.79%), Query Frame = 1

Query: 1180 MLIVFLSLGRWLEHIAKGKTSEALSKLLSLQAFEATIIVNDNQERKISXXXXXXXXXXXXXPGEKIPIDGRVVSGKS--RCDESLITGESMSVEKIPGSDVIGGTLNISGMLIIRATLVGEDSALNQIVKLVEEAQTSKAPIQELADKVAGLFVPGVIICSMFTLLIWIAIGYTNPNLLPGHSSINTDNTELIWKYAFQLAITVLSVACPCSLGLATPTAVMVGTGVGAINGILIKGGVPLEKMHQLDVIVFDKTGTITTGKPSVTNFVMCVENVTSQIRNCILLMLGAAESSSEHPIGKAILQYVRETCDINEMPQVVHSKSVSGFGLECSLKLQSDMFVPDSEIDNVLVKINDFQENNLTENLKETSVKWRKINEPVEVVLYLGNRNMMKEN-HISIPDKLDELMSRDEDNGRTVVLMAIDK-----VLLAMISIADQVKKEAALVVYTLEKMGVEVFLLTGDNHKTATAIAKEIGI-----------------------------RNVFAEVLPSHKVAKIQQIQNMSKYKRSWLFSCCSKPSKLTNVAMVGDGINDSPALAQADVGIAIGTGTDVAVEAADVVLIRNSLLDVIAAMKLSKDTVRRI 2898
            +L++  S+G +++    G   + L K L+  A     ++ D Q  +I  + V  G+++++  G   P DGR+V+     + D+S ITGES++ EK  G +V   +   +G   +  T  G+++ + +   LV +A   +    E+ + + G+ +  ++I ++  LL+W A  Y    ++             I +Y   L IT++ V  P  L     T + VG    A    +++    +E +  ++++  DKTGT+T  K S+      VE V+         +  + +      I KA L+       + E P+   + +          K +   F P    D V  K+    E+   E +    VK      P+ V+  +   + + E+ H +  +K+ EL SR    G   + +A  +      +L ++   D  + + A  +     +G+ + +LTGD    A    +++G+                              + FAEV P HK   ++ +QN     R +L            VAM GDG+ND+P+L +AD GIA+   TD A  AAD+V +   L  +I A+K S+    R+
Sbjct:  179 LLLLNASVG-FIQEFQAGSIVDELKKTLANTA----TVIRDGQLIEIPANEVVPGEILQLESGTIAPADGRIVTEDCFLQIDQSAITGESLAAEKHYGDEVFSSSTVKTGEAFMVVTATGDNTFVGRAAALVGQASGVEGHFTEVLNGI-GIILLVLVIATL--LLVWTACFYRTVGIVS------------ILRYT--LGITIIGV--PVGLPAVVTTTMAVGAAYLAKKQAIVQKLSAIESLAGVEILCSDKTGTLTKNKLSLHE-PYTVEGVSPDDLMLTACLAASRKKKGLDAIDKAFLK------SLIEYPKAKDALT----------KYKVLEFHP---FDPVSKKVTAVVESPEGERI--VCVK----GAPLFVLKTVEEDHPIPEDVHENYENKVAELASR----GFRALGVARKRGEGHWEILGVMPCMDPPRDDTAQTINEARNLGLRIKMLTGDAVGIAKETCRQLGLGTNIYNAERLGLGGGGDMPGSELADFVENADGFAEVFPQHKYRVVEILQN-----RGYL------------VAMTGDGVNDAPSLKKADTGIAVEGATDAARSAADIVFLAPGLSAIIDALKTSRQIFHRM 717

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BLAST of Copper-transporting ATPase 1 vs. Ensembl Yeast
Match: ENA5 (Protein with similarity to P-type ATPase sodium pumps; member of the Na+ efflux ATPase family [Source:SGD;Acc:S000002445])

HSP 1 Score: 81.2629 bits (199), Expect = 6.994e-16
Identity = 65/204 (31.86%), Postives = 102/204 (50.00%), Query Frame = 1

Query: 2437 DKVLLAMISIADQVKKEAALVVYTLEKMGVEVFLLTGDNHKTATAIAKEIGIRNV----FAEVLPSHKVAKIQQIQNMSKYKRSWL------FSCCSKPSKLTNV----------AMVGDGINDSPALAQADVGIAIG-TGTDVAVEAADVVLIRNSLLDVIAAMKLSKDTVRRIRQNFVAATMYNLIGIPIAAGALMPIGVVF 2985
            D V L +I I D  + E A  V    + G+ V +LTGD   TA AIA+E+GI       +++ +    V    Q   +S+ +   L       + CS  +K+  +          AM GDG+NDSP+L  A+VGIA+G  G+DV+ EA+D+VL  ++   ++ A++  +     I Q FV      L+   +A    + IG+VF
Sbjct:  638 DLVFLGLIGIYDPPRNETAGAVKKFHQAGINVHMLTGDFVGTAKAIAQEVGILPTNLYHYSQEIVDSMVMTGSQFDGLSEEEVDDLPVLPLVIARCSPQTKVRMIEALHRRKKFCAMTGDGVNDSPSLKMANVGIAMGINGSDVSKEASDIVLSDDNFASILNAVEEGRRMTDNI-QKFV----LQLLAENVAQALYLIIGLVF 836

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BLAST of Copper-transporting ATPase 1 vs. Ensembl Nematostella
Match: EDO47080 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RN63])

HSP 1 Score: 790.415 bits (2040), Expect = 0.000e+0
Identity = 451/1004 (44.92%), Postives = 636/1004 (63.35%), Query Frame = 1

Query:  145 DNIKTVVIDYEKNLVRICCHNDNCTYLTLCEAIENLGF----LIN-----------------------KNKETDNTKELFKCHMRIQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMGFDAEIFQFKEHTKDIIEVMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKLAPKKTNKYN-DHVGESIKKWKHSFLISLIFGVPTMIVMM--VFMYGFSHRMQVIHLKNGINVTVMVSNAPIXXXXXXXXXXXXXXXXXPVQFYGARYFYVQAYKSIKHGSANMDVLVVMATSVSYIYSFIVILVSMILRQDSSPQTFFETTPMLIVFLSLGRWLEHIAKGKTSEALSKLLSLQAFEATIIV------NDNQERKISXXXXXXXXXXXXXPGEKIPIDGRVVSGKSRCDESLITGESMSVEKIPGSDVIGGTLNISGMLIIRATLVGEDSALNQIVKLVEEAQTSKAPIQELADKVAGLFVPGVIICSMFTLLIWIAIGYTNPNLLPGHSSINTDNT-ELIWKYAFQLAITVLSVACPCSLGLATPTAVMVGTGVGAINGILIKGGVPLEKMHQLDVIVFDKTGTITTGKPSVTNFVMCVENVTSQIRNCILLMLGAAESSSEHPIGKAILQYVRETCDINEMPQVVHSKSVSGFGLECSLKLQSDMFV----------PDSEIDNVLVKINDFQENNLTENLKETSVKWRKINEPVEVVLYLGNRNMMKENHISIPDKLDELMSRDEDNGRTVVLMAIDKVLLAMISIADQVKKEAALVVYTLEKMGVEVFLLTGDNHKTATAIAKEIGIRNVFAEVLPSHKVAKIQQIQNMSKYKRSWLFSCCSKPSKLTNVAMVGDGINDSPALAQADVGIAIGTGTDVAVEAADVVLIRNSLLDVIAAMKLSKDTVRRIRQNFVAATMYNLIGIPIAAGALMPIGVVFMPWMASVAMA 3015
            D +++V +  +    R+    +  T   + EAIE++GF    L N                       K+ E D  +++ K ++ I+GMTC+SCV +IE  + K +GVKS L+ LL+   EV Y+ + I   +I   +  MGF  E+       ++++++ I GMTCSSCV+ IES L +  GIL   VAL T  G+FK+D +I  PRDI++AI+ +GF A LA   ++K   DH   SIKKW+ SFL+SLIFG+P   + +  VF+     R  V+ +  G+++  ++                +FL  +PVQ  G R+FYV AYK++KH S NMDVL+++AT+++Y+YS +V +V+M  +   SP TFF+T PML+VF+SLGRW+EH+AKGKTSEAL+KLLSLQ   A ++          +E  ISVDLV++ D++KV+PG KIP+DGRV+ G S  DESLITGESM V K  G  VIGGT+N +G ++I AT VG+D+ L QIVKLVEEAQTSKAPIQ+ AD ++G FVP VI+ S+ T +IW+ IGY++  ++    +   DN  E I  +AFQ+ ITVL++ACPC+LGLATPTAVMVGTG+GA NGILIKGG PLE  H++  +VFDKTGT+T GKP V    + V      ++  +L + G AE+SSEHP+G AI  Y ++      +      K+  G+GL C++    D+ +           DS   N+++ ++     +  +   ++++   ++ +  +V+  +GNR+ M++N + + D+++E M   E  G T +L+ I   L+ M+++AD VK EA + V TL++MG+ V LLTGDN KTA AIA+++GI+ VFAEVLPSHKV KI+ +Q                 +K    AMVGDGINDSPALAQA VGIAIGTGTDVAVEAAD+VLI++ L+DV AA+ LS+ TVRRI  NF  A +YN+IGIP AAG   P+GVV  PWMAS AMA
Sbjct:  192 DGVQSVKVSLDDKCARLEFAPEKVTPEQMREAIEDMGFDALLLGNVDEFVAVAGQMTGDWGVRFSSRKKHVEQDPLEDVEKIYLHIEGMTCASCVASIERALSKKEGVKSVLVGLLAQKAEVKYNKNRITTDEIVYHVTAMGFGCELMDKTGQGENVVDIRISGMTCSSCVHLIESSLIKRPGILQTSVALATSSGRFKYDTEITGPRDIIEAIKGLGFGAALADSSSSKDKVDHT-LSIKKWRRSFLVSLIFGLPVFAIFISYVFLEEAGKRPHVMVIP-GLSLENLL----------------MFLLCTPVQILGGRHFYVTAYKALKHRSTNMDVLIMLATTIAYVYSIVVCVVAMSEQSSHSPMTFFDTPPMLLVFISLGRWMEHVAKGKTSEALAKLLSLQPATAMLVKLKPGSHQITEETVISVDLVQRADVLKVVPGAKIPVDGRVIEGTSMADESLITGESMPVPKKVGDSVIGGTMNQNGAILIEATHVGQDTTLAQIVKLVEEAQTSKAPIQKFADTLSGYFVPIVILISIATFMIWVIIGYSDITIIRMVYNPKEDNRDEFIIGFAFQIGITVLAIACPCALGLATPTAVMVGTGIGAQNGILIKGGEPLETAHKVTAVVFDKTGTLTHGKPEVVKTALFVSPDICDLQ-LLLAVAGTAENSSEHPLGVAITTYAKKELSTENLGICSGFKAQPGYGLTCTVSGVEDLLLEPNQRQSKTSKDSTQGNLILPVDGSIARDFVKADLDSTIYDCRLGKQYKVL--IGNRDWMQQNGLVVTDEMEEDMVAHETIGHTAILIGIRDSLVGMMAVADTVKNEAQVAVSTLKRMGLRVVLLTGDNKKTAMAIARQVGIQQVFAEVLPSHKVEKIRALQ-----------------AKGFVTAMVGDGINDSPALAQAHVGIAIGTGTDVAVEAADIVLIKSDLMDVAAAIDLSRVTVRRIHLNFAFALLYNMIGIPFAAGVFEPLGVVMKPWMASAAMA 1157

HSP 2 Score: 101.293 bits (251), Expect = 1.237e-21
Identity = 68/228 (29.82%), Postives = 111/228 (48.68%), Query Frame = 1

Query:  112 LKIIEDFFQFNDNIKTVVIDYEKNLVRICCHNDNCTYLTLCEAIENLGF---------LINKN----------KETDNTKELFKCHMRIQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMGFDAEIFQFKEHTKDIIEVMI--QGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKL 732
            +K IE        +K + +  E+    +          +L  AI+++GF         ++ K           K  D  +E  +    + GMTC SCV +IE  + K  GV +  ++L      + Y   L     +A+ I D GF  E+   +  + D+  VMI  QGMTC+SCV TIE  ++++ G+ SVKV+L  +  + +F P+ ++P  + +AIE+MGFDA L
Sbjct:   10 VKTIETSMSSTSGVKNIKVSLEEKEAEVTFDPKITNGTSLANAIDDMGFEACLKRVVDILTKQEVAQSKGTSIKNADEREE--EIEFTVHGMTCQSCVKSIEKALSKSTGVLNVKVSLPKESAVIKYRKLLTSPEKLAELIEDAGF--EVVLPRSGSTDVKSVMITVQGMTCNSCVNTIEKNISKLDGVQSVKVSLDDKCARLEFAPEKVTPEQMREAIEDMGFDALL 233

HSP 3 Score: 100.523 bits (249), Expect = 2.205e-21
Identity = 56/157 (35.67%), Postives = 87/157 (55.41%), Query Frame = 1

Query:  319 IQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMGFDA------------EIFQFK-------EHTKDIIEVMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKL 732
            ++GMTC+SCV TIE  +    GVK+  ++L     EVT+DP +   + +A+ I+DMGF+A            E+ Q K       +  ++ IE  + GMTC SCV +IE  L++  G+L+VKV+L  E    K+   + SP  + + IE+ GF+  L
Sbjct:    1 MEGMTCNSCVKTIETSMSSTSGVKNIKVSLEEKEAEVTFDPKITNGTSLANAIDDMGFEACLKRVVDILTKQEVAQSKGTSIKNADEREEEIEFTVHGMTCQSCVKSIEKALSKSTGVLNVKVSLPKESAVIKYRKLLTSPEKLAELIEDAGFEVVL 157

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BLAST of Copper-transporting ATPase 1 vs. Ensembl Nematostella
Match: EDO43417 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RYT4])

HSP 1 Score: 205.682 bits (522), Expect = 1.732e-55
Identity = 161/537 (29.98%), Postives = 261/537 (48.60%), Query Frame = 1

Query: 1363 PGEKIPIDGRVVSGKSRCDESLITGESMSVEKIPGSDVIGGTLNISGMLIIRATLVGEDSALNQIVKLVEEAQTSKAPIQELADKVAGLFVPGVIICSMFTLLIWIAIGYTNPNLLPGHSSINTDNTELI-WKYAFQLAITVLSVACPCSLGLATPTAVMVGTGVGAINGILIKGGVPLEKMHQLDVIVFDKTGTITTGKPSVTNFVMCVENVTSQIRNCILLMLGAAESSSEHPIGKAILQYVRETCDINEMPQVVHSKSVSGFGLECSLKLQSDMF-VPDSEIDNVLVKINDFQENNLTENLKETSVKWRKINEPVEVVLYLGNRNMMKENHISIPDKLDELMSRD--------EDNGRTVVLMAIDKVLLAMISIADQVKKEAALVVYTLEKMGVEVFLLTGDNHKTATAIAKEIGIRNVFAEVLPSHKVAKIQQIQNMSKYKRSWLFSCCSKPSKL--TNVAMVGDGINDSPALAQADVGIAIGT-GTDVAVEAADVVLIRNSLLDVIAAMKLSKDTVRRIRQNFVAATMYNL 2934
            PG+ IP+DG VV G++  DES ITGE + VEK   S V  GT++ +G L I+ T    +S ++++ ++V+EAQ+S    +++ +  A  + P V++ S   + I        P +L G + + T   +L  W +    A+ +L VACPC+L + +P AV+      A  G LIK G  LE + +L+V+ FDKTGT+T GK  VT+     E+V       +L +    ES S HPI  AI         +NE    V S             ++S++F +P+                          VK  K++E   +   +  + ++  NH  + D+  E +            +  +TVV ++++  +  M+++AD ++      +  L   G++  ++TGDN +TA A+ + +G+    AE+ PS K+                   CC +   +   +V MVGDG+ND PALA AD+GIA+G  GT +AVEAADV L+ N+L  +   + L K     I QN   + +  L
Sbjct:  206 PGDLIPLDGIVVKGRASVDESSITGECLPVEKKVDSKVFSGTVDQNGYLEIKTTTDSSNSTVSRVAEMVQEAQSSSTRTEQIINHFAKYYTPLVVVTSALVIAI--------PAIL-GVAGVGTYQQDLHEWGHK---ALVLLVVACPCALVMTSPIAVVCSITAAARRGSLIKKGEHLETLAKLEVLAFDKTGTLTEGKFQVTDM----ESVYGVNEREVLRLAAGIESKSSHPIAAAI---------VNEFSGCVGS------------MVKSNVFSIPE--------------------------VKKFKLHEGKGISGIVEGKKVLVGNHSLVTDQCGEKLGSSMTDKYIQWSNESKTVVFVSVNSKVQLMVALADSIRPNTIDALDWLRHHGIQTSMITGDNARTAAAVKESLGLDECTAEMKPSDKLDP---------------HFCCVRRRNVGRVSVGMVGDGVNDGPALAAADLGIAMGAGGTALAVEAADVTLMSNNLAKIPELVSLGKFCRTIITQNIALSVVLKL 664

[Close]

BLAST of Copper-transporting ATPase 1 vs. Ensembl Nematostella
Match: EDO28080 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T7H1])

HSP 1 Score: 92.4337 bits (228), Expect = 3.571e-20
Identity = 93/393 (23.66%), Postives = 164/393 (41.73%), Query Frame = 1

Query: 1870 ILIKGGVPLEKMHQLDVIVFDKTGTITTGKPSVTNFVMCVENVTSQIRNCILLMLGAAESSSEHPIGKAILQYVRETCDINEMPQVVHSKSVSGFGLECSLKLQSDMFVPDSEIDNVLVKINDFQENNLTENLKETSVKWRKINEPVEVVLYLGNRNMMKENHISIPDKLDELMSRDEDNGRTVVLMAIDKVLLAMISIADQVKKEAALVVYTLEKMGVEVFLLTGDNHKTATAIAKEIGIRN--VFAEVLPSHKVAKIQQIQNMSKYKRSWLFSCCSKPSKLTNVAMVGDGINDSPALAQADVGIAIGTGTDVAVEAADVVLIRNSLLDVIAAMKLSKDTVRRIRQNFVAATMYNLIGIPIA-AGALMPIGVVFMPWMASVAMAASSICVVC 3039
            + +K    +E++ ++D IVFDKTGTIT+ K S  +F         ++ N  L  + +    S HP+ + I  Y+ +     E  +V     ++G G+E  +                                              EV   +G+ ++     +S+P+        +E + +T V + I+          +Q +K    +   L K   E+ +L+GDN      + +E+   N  +  +  P  K+  I+Q+Q   K                 NV M+GDG+ND+ ALAQ++VGI+I    +V   A D ++  +    +   +  SK+ +R I  +F  + +YNL+G+  A  G L P+       +A++ M  SSI VV 
Sbjct:    1 MYLKNATVIEQLAKVDTIVFDKTGTITSNKKSSVDFY------GEELTNSELKQIKSVIRGSNHPLSRKIYDYLPDF----EKVEVSQFNEITGKGIEAKIG---------------------------------------------EVFFQIGSSSL-----VSVPN--------EESSKQTKVHVRINGNYKGYYFFDNQYRKGVEALFEKLSKH-YELKILSGDNDGEKETL-QELLPENTELIFDRKPEQKLEYIEQLQKQGK-----------------NVMMIGDGLNDAGALAQSNVGISISENVNVFSPACDGIMDASQFSKIGYYLNFSKNAMRTIYMSFGLSLLYNLVGLSFAITGNLSPL-------IAAIIMPLSSITVVS 299

[Close]

BLAST of Copper-transporting ATPase 1 vs. Ensembl Nematostella
Match: EDO35616 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SL15])

HSP 1 Score: 75.0998 bits (183), Expect = 1.287e-13
Identity = 57/183 (31.15%), Postives = 89/183 (48.63%), Query Frame = 1

Query: 2449 LAMISIADQVKKEAALVVYTLEKMGVEVFLLTGDNHKTATAIAKEIGIR---------------------------NVFAEVLPSHKVAKIQQIQNMSKYKRSWLFSCCSKPSKLTNVAMVGDGINDSPALAQADVGIAIG-TGTDVAVEAADVVLIRNSLLDVIAAMKLSKDTVRRIRQNFV 2913
            L ++ + D  +      V TL   GV+V ++TGD+ +TA  IA+ +GI                            +VF  V P HKVA ++ +Q                      VAM GDG+ND+ AL +AD+GIA+G +GTDV+ EAA+++L+ +    ++AA++  K     I+ NFV
Sbjct:  530 LGIMGLLDPPRNGVREAVRTLLDSGVQVKMITGDSRETAITIAELLGIHFKGRPTLSGEELEALDGLQLSTIIDQVSVFYRVSPRHKVAIVKALQQHGHV-----------------VAMTGDGVNDAVALKRADIGIAMGKSGTDVSKEAAEMILVDDDFNTIMAAIEEGKGIFYNIK-NFV 694

[Close]

BLAST of Copper-transporting ATPase 1 vs. Ensembl Nematostella
Match: EDO36455 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SII2])

HSP 1 Score: 72.0182 bits (175), Expect = 1.347e-12
Identity = 63/225 (28.00%), Postives = 104/225 (46.22%), Query Frame = 1

Query: 2446 LLAMISIADQVKKEAALVVYTLEKMGVEVFLLTGDNHKTATAIAKEIGIRNVFAEV---------LPSHKVAKIQ-----------------QIQNMSKYKRSWLFSCCSKPSKL----------TNVAMVGDGINDSPALAQADVGIAIG-TGTDVAVEAADVVLIRNSLLDVIAAMKLSKDTVRRIRQNFVAATMYNLIG-IP--------IAAGALMPIGVV 2982
             + ++S+ D  +      V      G++VF++TGD+  TA AIA+ +GI +   E          +P  +V K Q                  I ++ K  +  +F+  S   KL            VA+ GDG+NDSPAL +AD+GIA+G +G+DV+ +AAD++L+ ++   ++  ++      R I  N   +  Y L   IP        I AG   P+G +
Sbjct:  621 FVGLMSMIDPPRAAVPDAVAKCRSAGIKVFMVTGDHPITAKAIAQGVGIISEGTETVEDISLRLEIPVEEVDKSQADAIVVHGGELKDMTDKDIDDILKNHKEIVFARTSPQQKLIIVEGCQRNGAIVAVTGDGVNDSPALKKADIGIAMGISGSDVSKQAADMILLDDNFASIVTGVEEG----RLIFDNLKKSIAYTLTSNIPEITPFLMFIVAGIPQPLGTI 841

[Close]

BLAST of Copper-transporting ATPase 1 vs. Ensembl Medaka
Match: atp7b (copper-transporting ATPase 2 [Source:NCBI gene;Acc:101171807])

HSP 1 Score: 820.846 bits (2119), Expect = 0.000e+0
Identity = 456/917 (49.73%), Postives = 624/917 (68.05%), Query Frame = 1

Query:  295 ELFKCHMRIQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMGFDAEIFQ--FKEHTKDIIEVMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKLAPKKTNKYNDHVGESIKKWKHSFLISLIFGVPTMIVMMVFMYGFSHRMQVIHLKNGINVTVMVSNAPIXXXXXXXXXXXXXXXXXPVQFYGARYFYVQAYKSIKHGSANMDVLVVMATSVSYIYSFIVILVSMILRQDSSPQTFFETTPMLIVFLSLGRWLEHIAKGKTSEALSKLLSLQAFEATIIV--NDNQ---ERKISXXXXXXXXXXXXXPGEKIPIDGRVVSGKSRCDESLITGESMSVEKIPGSDVIGGTLNISGMLIIRATLVGEDSALNQIVKLVEEAQTSKAPIQELADKVAGLFVPGVIICSMFTLLIWIAIGYTNPNL----LPGHSSINTDNTELIWKYAFQLAITVLSVACPCSLGLATPTAVMVGTGVGAINGILIKGGVPLEKMHQLDVIVFDKTGTITTGKPSVTNFVMCVENVTSQIRNCILLMLGAAESSSEHPIGKAILQYVRETCDINEMPQVVHSKSVSGFGLECSLKLQSDMFVPDSEIDNVLVKINDFQENNLTENLKETSVKWRKINEP----VEVVLYLGNRNMMKENHISIPDKLDELMSRDEDNGRTVVLMAIDKVLLAMISIADQVKKEAALVVYTLEKMGVEVFLLTGDNHKTATAIAKEIGIRNVFAEVLPSHKVAKIQQIQNMSKYKRSWLFSCCSKPSKLTNVAMVGDGINDSPALAQADVGIAIGTGTDVAVEAADVVLIRNSLLDVIAAMKLSKDTVRRIRQNFVAATMYNLIGIPIAAGALMPIGVVFMPWMA 3000
            E+ KC + + GMTC+SCV  IE  +LK +G+ S L++L++   EV YD  ++ A  +A  I D+GF A++ +    EH K  +++ I GMTC+SCV+ IESKL   +GIL   VAL T K   +FD +I+ PRDI+  I+ +GF+A L  K      DH  E I++W++SFL SL+FG+P M +M+  M      M  +H ++G ++    + AP    GLSL NL+ FL  +PVQ +G RYFY+QAY+S+KH +ANMDVL+V+AT+++Y+YS +V++++M+ R   SP TFF+T PML VF+SLGRWLEH+AK KTSEAL+KL+SLQA +AT++    D+    E ++ V+LV++GD+VK++PG K PIDG+V+ G S  DESLITGE M V K  GS VI G++N  G L++ AT VG ++ L+QIVKLVEEAQTSKAPIQ+ AD+++G FVP ++  S+ TL+ W+ IG+ N  +     PG++  N    E+I ++AFQ +ITVLS+ACPCSLGLATPTAVMVGTGVGA NGILIKGG PLE  H+++V++FDKTGTIT G P VT  ++  E     +R  IL ++G AE+SSEHP+G A+ ++ ++    + M      ++V G G+ C +          S +D++L + +       T+   E+S+   +   P        + +GNR  M+ N + I   +D  MS  E  G+T VL+AID VL AMI+IAD VK E+AL V+TL  MGVEV ++TGDN  TA AIA ++GIR VFAEVLPSHKVAK+Q++Q                  +   VAMVGDGINDSPALA ADVGIAIGTGTDVA+EAAD+VLIRN+LLDV+A+++LSK TVRRIR NFV A +YNL+GIPIAAG  MP+G+V  PWM 
Sbjct:  354 EIKKCFVLVAGMTCTSCVANIEKNILKHRGIVSVLVSLMAGKAEVKYDAGVLSAPAVAQLIQDLGFGAKLIEDHAGEHGK--LDLTITGMTCASCVHKIESKLVATKGILVASVALATRKAHIQFDSEILGPRDIIRIIQSLGFEASLEKKGFKNNVDHT-EEIRQWRNSFLFSLVFGLPVMGLMVYMMV-----MDTLHQEHGGSMPEDQNVAP----GLSLLNLIFFLLCTPVQIFGGRYFYIQAYRSLKHHTANMDVLIVLATTIAYVYSCLVLVIAMVERASQSPVTFFDTPPMLFVFISLGRWLEHVAKRKTSEALAKLMSLQATDATVVTVGPDHSIISEEQVMVELVQRGDVVKIVPGGKFPIDGKVIEGSSMADESLITGEPMPVSKTVGSLVIAGSINAHGSLLVEATHVGAETTLSQIVKLVEEAQTSKAPIQQFADRISGYFVPFIVFVSLATLVAWLVIGFVNFTIVTENFPGYNQ-NISKAEVIIRFAFQASITVLSIACPCSLGLATPTAVMVGTGVGAQNGILIKGGEPLEMAHKINVVMFDKTGTITNGVPQVTRVLVLWETARMPLRQ-ILAVVGTAEASSEHPLGVAVTKHCKDELGSDAMGFCQDFQAVPGCGISCRV----------SNVDHLLQQQSFLLPGATTD---ESSLLAAQEAPPTVGGASYSVLIGNREWMRRNGLHIKADVDAAMSSHETKGQTAVLVAIDGVLCAMIAIADTVKPESALAVHTLNSMGVEVVMVTGDNRCTAKAIAAQVGIRKVFAEVLPSHKVAKVQELQE-----------------RGLRVAMVGDGINDSPALACADVGIAIGTGTDVAIEAADIVLIRNNLLDVVASIELSKKTVRRIRINFVFALIYNLLGIPIAAGVFMPVGLVLQPWMG 1226

HSP 2 Score: 111.694 bits (278), Expect = 2.816e-24
Identity = 57/175 (32.57%), Postives = 91/175 (52.00%), Query Frame = 1

Query:  310 HMRIQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMGFDAEIFQFKEHTKDII-------------EVMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKLAPKKTNKYNDHVGESIKKWKH 795
             M++ GM C SCV +IE ++ +L GV    ++L     EV + P +I   ++ D I DMGF A +   +  + D+               + I GM+CSSCV +IE +++Q +G+ S+ V+L  EK    FDP +  P  +  AIE+MGFDA L   + +  N     S+  ++ 
Sbjct:  157 QMKVDGMHCRSCVESIERRIRELPGVVQIRVSLEEAKAEVMFQPLVITQQELQDQIEDMGFSATLMLKETSSGDLTFVQRDLNMSIQNTTIWIAGMSCSSCVQSIEGRISQTRGVKSIVVSLKEEKATISFDPGLTEPEQLRAAIEDMGFDASLKEPERSIQNQEKSRSVDFYQQ 331

HSP 3 Score: 67.0106 bits (162), Expect = 1.026e-10
Identity = 37/138 (26.81%), Postives = 71/138 (51.45%), Query Frame = 1

Query:  337 SSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMGFDAEIFQFKEHTKDIIEVMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKLAPKKTN 750
            S+ +  +E  +  L GV +    +   + +V YD       +IA  +  +G   E           +++ + GM C SCV +IE ++ ++ G++ ++V+L   K +  F P +I+ +++ D IE+MGF A L  K+T+
Sbjct:   99 STALEAVETTLPALDGVLAVTWLVPDALVQVDYDSSATTTKEIAMQLQALGCTVEA---------AVQMKVDGMHCRSCVESIERRIRELPGVVQIRVSLEEAKAEVMFQPLVITQQELQDQIEDMGFSATLMLKETS 227

HSP 4 Score: 58.5362 bits (140), Expect = 4.009e-8
Identity = 34/107 (31.78%), Postives = 60/107 (56.07%), Query Frame = 1

Query:  229 LCEAIENLGFLINKNKETDNTKELFKCHMRIQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMGFDAEIFQ--FK---EHTKDI 534
            + + I++LGF        D+  E  K  + I GMTC+SCVH IE++++  KG+  A + L +    + +D +++   DI   I  +GF+A + +  FK   +HT++I
Sbjct:  410 VAQLIQDLGF--GAKLIEDHAGEHGKLDLTITGMTCASCVHKIESKLVATKGILVASVALATRKAHIQFDSEILGPRDIIRIIQSLGFEASLEKKGFKNNVDHTEEI 514

[Close]

BLAST of Copper-transporting ATPase 1 vs. Ensembl Medaka
Match: atp7a (copper-transporting ATPase 1 [Source:NCBI gene;Acc:101164902])

HSP 1 Score: 814.298 bits (2102), Expect = 0.000e+0
Identity = 465/930 (50.00%), Postives = 625/930 (67.20%), Query Frame = 1

Query:  304 KCHMRIQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMGFDAEIFQFKEHTKDIIEVMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKLAPK-KTNKYNDHVGESIKKWKHSFLISLIFGVPTMIVMMV------FMYGFSHRMQVIHLKNGINVTVMVSNAPIXXXXXXXXXXXXXXXXXPVQFYGARYFYVQAYKSIKHGSANMDVLVVMATSVSYIYSFIVILVSMILRQDSSPQTFFETTPMLIVFLSLGRWLEHIAKGKTSEALSKLLSLQAFEATIIV--NDN---QERKISXXXXXXXXXXXXXPGEKIPIDGRVVSGKSRCDESLITGESMSVEKIPGSDVIGGTLNISGMLIIRATLVGEDSALNQIVKLVEEAQTSKAPIQELADKVAGLFVPGVIICSMFTLLIWIAIGYTNPNLL----PGHSSINTDNTELIWKYAFQLAITVLSVACPCSLGLATPTAVMVGTGVGAINGILIKGGVPLEKMHQLDVIVFDKTGTITTGKPSVTNFVMCVENVTSQIRNCILLMLGAAESSSEHPIGKAILQYVRETCDINEMPQVVHSKSVSGFGLECSLK------LQSDMFVPDSEIDN----VLVKINDFQENNLTENLKETSVKWRKINEPVEVVLYLGNRNMMKENHISIPDKLDELMSRDEDNGRTVVLMAIDKVLLAMISIADQVKKEAALVVYTLEKMGVEVFLLTGDNHKTATAIAKEIGIRNVFAEVLPSHKVAKIQQIQNMSKYKRSWLFSCCSKPSKLTNVAMVGDGINDSPALAQADVGIAIGTGTDVAVEAADVVLIRNSLLDVIAAMKLSKDTVRRIRQNFVAATMYNLIGIPIAAGALMPIGVVFMPWMASVAMA 3015
            KC+++I GMTC+SCV  IE  +    G+   L+ L+++  EV Y+P++I    I + + ++GF A + +  E +   +E++I+GMTC+SCV+ IES L + +GI    VAL T K   KFD +++ PRDI+  IE +GF A L  + ++  + DH  E I++W+ SFLISLIF VP M +M+        M    H    +  +N  + T+ +     LFPGLS+ NLL F+F  PVQF G RYFY+QAYK++KH SANMDVL+V+ATSV++ YS +V++V+M+ R   +P TFF+T PML VF+SLGRWLE IAK KTSEALSKL+SLQA EAT++   +DN    E ++ V+LV++GD+VKV+PG K P+DGRV+ G S  DESLITGE+M V K PGS VI G++N +G L++ AT VG D+ L+QIVKLVEEAQTSKAPIQ+ ADK++G FVP ++  S+ TL++WI IG+ + +L+    PG++  +   +E + ++AFQ +ITVL +ACPCSLGLATPTAVMVGTGVGA NGILIKGG PLE  H++  +VFDKTGTIT G P V      VE     +   +L ++G AE++SEHP+G AI +Y ++      +      ++V G G+ C +        Q D    DSE +N    VLV+I+D + ++ +  L             + VVL +GNR  M+ N + I  ++DE M   E  GRT VL+A++ +L AMI+I+D VK EA L V TL  MG+EV L+TGDN KTA  IA ++GIR VFAEVLPSHKVAK++Q+Q   K                  VAMVGDG+NDSPALA ADVGIAIGTGTDVA+EAADVVLIRN LLDV+ ++ LSK TV+RIR NFV A +YNL+GIPIAAG  +PIG+V  PWM S AMA
Sbjct:  482 KCYIQIGGMTCASCVSNIERNLKNEPGIYFVLVALMASKAEVRYNPEVIDPPKIVECVKELGFTASVMENYEGSNGNLELVIRGMTCASCVHKIESNLMKEKGIEYASVALATNKAHVKFDSEVLGPRDIIKLIENLGFKASLVKRDRSASHLDHSKE-IRQWRKSFLISLIFCVPVMGMMIYMMVMDHHMNASHHHNATVEDRNHYHSTMFLERQ--LFPGLSIMNLLSFIFCVPVQFIGGRYFYIQAYKALKHKSANMDVLIVLATSVAFSYSLVVLIVAMVERAKVNPITFFDTPPMLFVFISLGRWLEQIAKSKTSEALSKLMSLQATEATVVTLGSDNVILSEEQVDVELVQRGDVVKVVPGGKFPVDGRVLEGHSMADESLITGEAMPVTKKPGSTVIAGSINQNGSLLVSATHVGMDTTLSQIVKLVEEAQTSKAPIQQYADKISGYFVPFIVAVSLLTLIVWIIIGFLDFSLVKKYFPGYNE-SISRSETVIRFAFQASITVLCIACPCSLGLATPTAVMVGTGVGAQNGILIKGGEPLEMAHKVQAVVFDKTGTITYGAPKVVQVKTVVEGNKMPLSR-LLAIVGTAENNSEHPLGAAITKYCKQELGTESLGTCTDFQAVPGCGVRCQVSNTETVVKQGD---SDSEDNNHRNSVLVQISDTRTSSSSHPLIMDPQPLSSGPTDLYVVL-IGNREWMRRNFLEITAEIDEAMMEHERRGRTAVLVAVNNMLCAMIAISDTVKPEAELAVQTLTNMGLEVVLMTGDNSKTARVIAAQVGIRKVFAEVLPSHKVAKVEQLQQAGKI-----------------VAMVGDGVNDSPALAMADVGIAIGTGTDVAIEAADVVLIRNDLLDVVGSIDLSKKTVKRIRINFVFALIYNLVGIPIAAGVFLPIGLVLQPWMGSAAMA 1385

HSP 2 Score: 97.4413 bits (241), Expect = 5.672e-20
Identity = 57/172 (33.14%), Postives = 86/172 (50.00%), Query Frame = 1

Query:  310 HMRIQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMGFDAEI------------------------FQFKEHTKDIIE-------VMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKL 732
            ++ I+GMTC+SCV +IE  + + KGV SA ++L    G   YDP L    ++ + + DMGFDA +                        F  KE  +   E       + I GMTC+SCV  IE  L    GI  V VAL   K + +++P++I P  I++ ++E+GF A +
Sbjct:  377 NIHIEGMTCNSCVQSIEGMISQRKGVVSAQVSLADHQGIFEYDPLLTSPQELREAVEDMGFDAFLPETNSLLEPNITTSASTAPDQGKEFDPKEAHRGSTEGTHSKCYIQIGGMTCASCVSNIERNLKNEPGIYFVLVALMASKAEVRYNPEVIDPPKIVECVKELGFTASV 548

HSP 3 Score: 87.8113 bits (216), Expect = 5.668e-17
Identity = 50/167 (29.94%), Postives = 85/167 (50.90%), Query Frame = 1

Query:  319 IQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDM---GFDAE-----------------IFQ---------FKEHTKDIIEVMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKL 732
            ++GM C SCV  I++ +  L GV S  ++L      + YDP  +  S +   I  +    F  E                 + Q         F +     + + I+GMTC+SCV +IE  ++Q +G++S +V+L   +G F++DP + SP+++ +A+E+MGFDA L
Sbjct:  275 VKGMHCRSCVVNIQDNISLLPGVSSVEVSLEKEQATICYDPHKVTVSALQQAIEALPPGNFKVEAPGSTNPVTSARAQPACVTQAKPAALQPCFTQPLVSTVNIHIEGMTCNSCVQSIEGMISQRKGVVSAQVSLADHQGIFEYDPLLTSPQELREAVEDMGFDAFL 441

HSP 4 Score: 62.3882 bits (150), Expect = 2.918e-9
Identity = 42/173 (24.28%), Postives = 83/173 (47.98%), Query Frame = 1

Query:  226 TLCEAIENLGFLINKNKETDNTKELFKCHMRIQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMGF-DAEIFQFKEHTKDIIEVMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKLAPK 741
            +L EAIE++GF  +    +  T    +  +        +       ++ + KGV     +       +T+ P LI   +++  +  +   D +  + K+    ++++ I+GMTC SCV TIE K+ ++ GI  +KV L +++    + P +I+ + I++ I   GF A +  K
Sbjct:   61 SLSEAIEDMGFESSFPDGSTATAVSTETQLIPTSALAPAAHQEAREKLSQTKGVLEVCESPSQKDLHITFAPSLISTLELSKVVESLTLADVQTSKMKDDGVALLKLRIEGMTCHSCVTTIEGKIGKLNGIQKIKVVLESKEATIIYLPYLITHQSIVEQIAFAGFKASVKSK 233

HSP 5 Score: 56.225 bits (134), Expect = 2.104e-7
Identity = 22/66 (33.33%), Postives = 41/66 (62.12%), Query Frame = 1

Query:  535 IEVMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKL 732
            + + ++GMTC SCV +IE ++  + G++ ++V+L  +     FD    SP  + +AIE+MGF++  
Sbjct:   10 VALKVEGMTCGSCVQSIEQRIGSLPGVIHIRVSLEQKTATLIFDQGQQSPESLSEAIEDMGFESSF 75

HSP 6 Score: 53.5286 bits (127), Expect = 1.421e-6
Identity = 38/152 (25.00%), Postives = 71/152 (46.71%), Query Frame = 1

Query:  313 MRIQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMGFDAEIFQFKEHTKDIIEVMIQGMTCSSCVYTIES--KLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKLAPKKTNKYND 762
            ++++GMTC SCV +IE ++  L GV    ++L      + +D        +++ I DMGF++        T    E  +   +  +     E+  KL+Q +G+L V  + + +     F P +IS  ++   +E +     LA  +T+K  D
Sbjct:   12 LKVEGMTCGSCVQSIEQRIGSLPGVIHIRVSLEQKTATLIFDQGQQSPESLSEAIEDMGFESSFPDGSTATAVSTETQLIPTSALAPAAHQEAREKLSQTKGVLEVCESPSQKDLHITFAPSLISTLELSKVVESL----TLADVQTSKMKD 159

[Close]

BLAST of Copper-transporting ATPase 1 vs. Ensembl Medaka
Match: atp7a (copper-transporting ATPase 1 [Source:NCBI gene;Acc:101173428])

HSP 1 Score: 782.711 bits (2020), Expect = 0.000e+0
Identity = 485/1072 (45.24%), Postives = 651/1072 (60.73%), Query Frame = 1

Query:  121 IEDFFQFNDNIKTVVIDYEKNLVRICCHNDNCTYLTLCEAIENL---GFLINKNKETD---------------NTKELFKC---------HMRIQGMTCSSCVHTIENQVLKLKGVKSA----------------------------------------------------LINLLSTIGEVTYDPDLIMASDIADTINDMGFDAEIFQFKEHTKDIIEVMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKLAPK-KTNKYNDHVGESIKKWKHSFLISLIFGVPTMIVMMV------FMYGFSHRMQVIHLKNGINVTVMVSNAPIXXXXXXXXXXXXXXXXXPVQFYGARYFYVQAYKSIKHGSANMDVLVVMATSVSYIYSFIVILVSMILRQDSSPQTFFETTPMLIVFLSLGRWLEHIAKGKTSEALSKLLSLQAFEATIIV--NDN---QERKISXXXXXXXXXXXXXPGEKIPIDGRVVSGKSRCDESLITGESMSVEKIPGSDVIGGTLNISGMLIIRATLVGEDSALNQIVKLVEEAQTSKAPIQELADKVAGLFVPGVIICSMFTLLIWIAIGYTNPNLL----PGH-SSINTDNTELIWKYAFQLAITVLSVACPCSLGLATPTAVMVGTGVGAINGILIKGGVPLEKMHQLDVIVFDKTGTITTGKPSVTNFVMCVENVTSQIRNCILLMLGAAESSSEHPIGKAILQYVRETCDINEMPQVVHSKSVSGFGLECSLK------LQSDMFVPDSEIDN----VLVKINDFQENNLTENLKETSVKWRKINEPVEVVLYLGNRNMMKENHISIPDKLDELMSRDEDNGRTVVLMAI-DKVLLAMISIADQVKKEAALVVYTLEKMGVEVFLLTGDNHKTATAIAKEIGIRNVFAEVLPSHKVAKIQQIQNMSKYKRSWLFSCCSKPSKLTNVAMVGDGINDSPALAQADVGIAIGTGTDVAVEAADVVLIRNSLLDVIAAMKLSKDTVRRIRQNFVAATMYNLIGIPIAAGALMPIGVVFMPWMASVAMA 3015
            I+D       + +V +  EK    IC      T   L +AIE L    F +     T+                   L  C         ++ I+GMTC+SCV +IE  + + KGV SA                                                    L+ L+++  EV Y+P++I    I + + ++GF A + +  E +   +E++++GMTC+SCV+ IES L + +GI    VAL T     KFD +++ PRDI+  IE +GF A L  + ++  + DH  E I++W+ SFLISLIF VP M +M+        M    H    +  +N  + T+ +     LFPGLS+ NLL F+F  PVQF G RYFY+QAYK++KH SANMDVL+V+ATSV++ YS +V++V+M+ R   +P TFF+T PML VF+SLGRWLE IAK KTSEALSKL+SLQA EAT++   +DN    E ++ V+LV++GD+VKV+PG K P+DGRV+ G S  DESLITGE+M V K PGS VI G++N +G L++ AT VG D+ L+QIVKLVEEAQTSKAPIQ+ ADK++G FVP ++  S+ TL++WI IG+ + +L+    PG+  SI+T  TE + ++AFQ +ITVL +ACPC LGLATPTAVMVGTGVGA NGILIKGG PLE  H++  IVFDKTGTIT G P V      VE     +   +L ++G AE++SEHP+G AI +Y ++      +      ++V G G+ C +        Q D    DSE +N    VLV+I+D + ++ +  L             + VVL +GNR  M+ N + I  ++DE M   E  GRT VL+++   +L AMI+I+D VK EA L V TL  MG+EV L+TGDN KTA  IA ++GIR VFAEVLPSHKVAK++Q+Q   K                  VAMVGDG+NDSPALA ADVGIAIGTGTDVA+EAADVVLIRN LLDV+ ++ LSK TV+RIR NFV A +YNL+GIPIAAG  +PIG+V  PWM S AMA
Sbjct:  287 IQDNISLLPGVSSVEVSLEKEQATICYDPHKVTVSALQQAIEALPPGNFKVEAPGSTNPVTSARAQPASVTQAKPAALQPCCTQPLVSTVNIHIEGMTCNSCVQSIEGMISQRKGVVSAQVSLADHQGIFEYDPLLTSPQELREAVEDMGFDAFLPGKSKKSGKGLWIYFVLVALMASKAEVRYNPEVIDPPRIVECVKELGFTASVMENYEGSDRNLELVVRGMTCASCVHKIESNLMKEKGIEYASVALATNIAHIKFDSEVLGPRDIIKLIENLGFKASLVKRDRSASHLDHSKE-IRQWRKSFLISLIFCVPVMGMMIYMMVMDHHMNASHHHNATVEDRNHYHSTMFLERQ--LFPGLSIMNLLSFIFCVPVQFIGGRYFYIQAYKALKHKSANMDVLIVLATSVAFSYSLVVLIVAMVERAKVNPITFFDTPPMLFVFISLGRWLEQIAKSKTSEALSKLMSLQATEATVVALGSDNVILSEEQVDVELVQRGDVVKVVPGGKFPVDGRVLEGHSMADESLITGEAMPVTKKPGSTVIAGSINQNGSLLVSATHVGMDTTLSQIVKLVEEAQTSKAPIQQYADKISGYFVPFIVAVSLLTLIVWIIIGFLDFSLVKKYFPGYDKSIST--TETVIRFAFQTSITVLCIACPCCLGLATPTAVMVGTGVGAQNGILIKGGEPLEMAHKVQAIVFDKTGTITYGAPKVVQVKTVVEGNKMPLSR-LLAIVGTAENNSEHPLGAAITKYCKQELGTESLGTCTDFQAVPGCGVRCQVSNTETVVKQGD---SDSEDNNHWNSVLVQISDTRTSSSSHPLIMDPQPLSSGPTDLYVVL-IGNREWMRRNFLEITAEIDEAMMEHERRGRTAVLVSLCADMLCAMIAISDTVKPEAELAVQTLTNMGLEVVLMTGDNSKTARVIAAQVGIRKVFAEVLPSHKVAKVEQLQQAGKI-----------------VAMVGDGVNDSPALAMADVGIAIGTGTDVAIEAADVVLIRNDLLDVVGSIDLSKKTVKRIRINFVFALIYNLVGIPIAAGVFLPIGLVLQPWMGSAAMA 1331

HSP 2 Score: 62.003 bits (149), Expect = 4.166e-9
Identity = 31/107 (28.97%), Postives = 60/107 (56.07%), Query Frame = 1

Query:  424 EVTYDPDLIMASDIADTINDMGF-DAEIFQFKEHTKDIIEVMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKLAPK 741
             +T+ P LI   +++  +  +   D +  + K+    ++++ ++GMTC SCV TIE K+ ++ GI  VKV L +++    + P +I+ + I++ I   GF A +  K
Sbjct:  127 HITFAPSLISTLELSKVVESLTLADVQTSKMKDDGVALLKLRVEGMTCHSCVTTIEGKIGKLNGIQKVKVVLESKEATIIYLPYLITHQSIVEQIAFAGFKASVKSK 233

HSP 3 Score: 56.225 bits (134), Expect = 2.217e-7
Identity = 23/71 (32.39%), Postives = 42/71 (59.15%), Query Frame = 1

Query:  535 IEVMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKLAPKKT 747
            + + ++GMTC SCV +IE ++  + G++ ++V+L  +     FD    SP  + +AIE+MGF++      T
Sbjct:   10 VALKVEGMTCGSCVQSIEQRIGSLPGVIHIRVSLEQKTATLIFDQGQQSPESLSEAIEDMGFESSFPDGST 80

HSP 4 Score: 53.5286 bits (127), Expect = 1.461e-6
Identity = 39/155 (25.16%), Postives = 73/155 (47.10%), Query Frame = 1

Query:  313 MRIQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMGFDAEIFQFKE-HTKDIIEVMIQGMTCSSCV----YTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKLAPKKTNKYND 762
            ++++GMTC SCV +IE ++  L GV    ++L      + +D        +++ I DMGF++    F +  T  ++    Q +  S+           KL+Q +G+L V  + + +     F P +IS  ++   +E +     LA  +T+K  D
Sbjct:   12 LKVEGMTCGSCVQSIEQRIGSLPGVIHIRVSLEQKTATLIFDQGQQSPESLSEAIEDMGFES---SFPDGSTATVVSTETQLIPTSALAPAAHQEAREKLSQTKGVLEVCESPSQKDLHITFAPSLISTLELSKVVESL----TLADVQTSKMKD 159

[Close]

BLAST of Copper-transporting ATPase 1 vs. Ensembl Medaka
Match: si:dkey-28b4.8 (sarcoplasmic/endoplasmic reticulum calcium ATPase 2-like [Source:NCBI gene;Acc:101159722])

HSP 1 Score: 80.4925 bits (197), Expect = 7.914e-15
Identity = 55/238 (23.11%), Postives = 115/238 (48.32%), Query Frame = 1

Query: 2323 YLGNRNMMKENHISIPDKLDELMSRDEDNGRTVVLMAIDKVLLAMISIADQVKKEAALVVYTLEKMGVEVFLLTGDNHKTATAIAKEIGI------------------RNVFAEVLPSHKVAKIQQIQNMSKYKRSWLFSCCSKPSKLTNV-AMVGDGINDSPALAQADVGIAIGTGTDVAVEAADVVLIRNSLLDVIAAMKLSKDTVRRIRQ---NFVAATMYNLIGIPIAAGALMP 2970
            +   R+ ++   ++  D   ++ S + +N  T V    D   +  + + D  +KE    V    + G+ V ++TGDN  TA +I + +GI                     F E+ P+ +    Q ++  ++ + +           L+++ AM GDG+ND+PAL +A++GIA+G+GT VA  A++++L  ++   ++AA++  +     ++Q     +++ +  ++ I + A   MP
Sbjct:  553 WTSGRDTLRCLAMATRDTPPDINSLNLENSATFVDYETDLTFVGCVGMLDPPRKEVLGAVRMCRQAGIRVIMITGDNKGTALSICRRVGIITEQEEEQGGAGIMGGLTGREFDELPPALQRQACQTVRCFARVEPAHKSRIVEYLQSLSDITAMTGDGVNDAPALKKAEIGIAMGSGTAVAKSASEMILADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNIGEVVCIFLTAALGMP 790

[Close]

BLAST of Copper-transporting ATPase 1 vs. Ensembl Medaka
Match: si:dkey-28b4.8 (sarcoplasmic/endoplasmic reticulum calcium ATPase 2-like [Source:NCBI gene;Acc:101159722])

HSP 1 Score: 80.4925 bits (197), Expect = 8.007e-15
Identity = 55/238 (23.11%), Postives = 115/238 (48.32%), Query Frame = 1

Query: 2323 YLGNRNMMKENHISIPDKLDELMSRDEDNGRTVVLMAIDKVLLAMISIADQVKKEAALVVYTLEKMGVEVFLLTGDNHKTATAIAKEIGI------------------RNVFAEVLPSHKVAKIQQIQNMSKYKRSWLFSCCSKPSKLTNV-AMVGDGINDSPALAQADVGIAIGTGTDVAVEAADVVLIRNSLLDVIAAMKLSKDTVRRIRQ---NFVAATMYNLIGIPIAAGALMP 2970
            +   R+ ++   ++  D   ++ S + +N  T V    D   +  + + D  +KE    V    + G+ V ++TGDN  TA +I + +GI                     F E+ P+ +    Q ++  ++ + +           L+++ AM GDG+ND+PAL +A++GIA+G+GT VA  A++++L  ++   ++AA++  +     ++Q     +++ +  ++ I + A   MP
Sbjct:  547 WTSGRDTLRCLAMATRDTPPDINSLNLENSATFVDYETDLTFVGCVGMLDPPRKEVLGAVRMCRQAGIRVIMITGDNKGTALSICRRVGIITEQEEEQGGAGIMGGLTGREFDELPPALQRQACQTVRCFARVEPAHKSRIVEYLQSLSDITAMTGDGVNDAPALKKAEIGIAMGSGTAVAKSASEMILADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNIGEVVCIFLTAALGMP 784

[Close]

BLAST of Copper-transporting ATPase 1 vs. Planmine SMEST
Match: SMESG000058134.1 (SMESG000058134.1)

HSP 1 Score: 2070.82 bits (5364), Expect = 0.000e+0
Identity = 1083/1083 (100.00%), Postives = 1083/1083 (100.00%), Query Frame = 1

Query:   52 MDEEIYHFEILIKEVNDKNQLKIIEDFFQFNDNIKTVVIDYEKNLVRICCHNDNCTYLTLCEAIENLGFLINKNKETDNTKELFKCHMRIQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMGFDAEIFQFKEHTKDIIEVMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKLAPKKTNKYNDHVGESIKKWKHSFLISLIFGVPTMIVMMVFMYGFSHRMQVIHLKNGINVTVMVSNAPIXXXXXXXXXXXXXXXXXPVQFYGARYFYVQAYKSIKHGSANMDVLVVMATSVSYIYSFIVILVSMILRQDSSPQTFFETTPMLIVFLSLGRWLEHIAKGKTSEALSKLLSLQAFEATIIVNDNQERKISXXXXXXXXXXXXXPGEKIPIDGRVVSGKSRCDESLITGESMSVEKIPGSDVIGGTLNISGMLIIRATLVGEDSALNQIVKLVEEAQTSKAPIQELADKVAGLFVPGVIICSMFTLLIWIAIGYTNPNLLPGHSSINTDNTELIWKYAFQLAITVLSVACPCSLGLATPTAVMVGTGVGAINGILIKGGVPLEKMHQLDVIVFDKTGTITTGKPSVTNFVMCVENVTSQIRNCILLMLGAAESSSEHPIGKAILQYVRETCDINEMPQVVHSKSVSGFGLECSLKLQSDMFVPDSEIDNVLVKINDFQENNLTENLKETSVKWRKINEPVEVVLYLGNRNMMKENHISIPDKLDELMSRDEDNGRTVVLMAIDKVLLAMISIADQVKKEAALVVYTLEKMGVEVFLLTGDNHKTATAIAKEIGIRNVFAEVLPSHKVAKIQQIQNMSKYKRSWLFSCCSKPSKLTNVAMVGDGINDSPALAQADVGIAIGTGTDVAVEAADVVLIRNSLLDVIAAMKLSKDTVRRIRQNFVAATMYNLIGIPIAAGALMPIGVVFMPWMASVAMAASSICVVCXXXXXXXXXXPNEDQLANQEFKNHLECLKYGDMEVGVNLGKDIILPXXXXXXXXXXXXXXXXXXXXXXXXKPNVSDRIALLENFKND 3300
            MDEEIYHFEILIKEVNDKNQLKIIEDFFQFNDNIKTVVIDYEKNLVRICCHNDNCTYLTLCEAIENLGFLINKNKETDNTKELFKCHMRIQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMGFDAEIFQFKEHTKDIIEVMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKLAPKKTNKYNDHVGESIKKWKHSFLISLIFGVPTMIVMMVFMYGFSHRMQVIHLKNGINVTVMVSNAPILFPGLSLENLLLFLFSSPVQFYGARYFYVQAYKSIKHGSANMDVLVVMATSVSYIYSFIVILVSMILRQDSSPQTFFETTPMLIVFLSLGRWLEHIAKGKTSEALSKLLSLQAFEATIIVNDNQERKISVDLVKKGDLVKVLPGEKIPIDGRVVSGKSRCDESLITGESMSVEKIPGSDVIGGTLNISGMLIIRATLVGEDSALNQIVKLVEEAQTSKAPIQELADKVAGLFVPGVIICSMFTLLIWIAIGYTNPNLLPGHSSINTDNTELIWKYAFQLAITVLSVACPCSLGLATPTAVMVGTGVGAINGILIKGGVPLEKMHQLDVIVFDKTGTITTGKPSVTNFVMCVENVTSQIRNCILLMLGAAESSSEHPIGKAILQYVRETCDINEMPQVVHSKSVSGFGLECSLKLQSDMFVPDSEIDNVLVKINDFQENNLTENLKETSVKWRKINEPVEVVLYLGNRNMMKENHISIPDKLDELMSRDEDNGRTVVLMAIDKVLLAMISIADQVKKEAALVVYTLEKMGVEVFLLTGDNHKTATAIAKEIGIRNVFAEVLPSHKVAKIQQIQNMSKYKRSWLFSCCSKPSKLTNVAMVGDGINDSPALAQADVGIAIGTGTDVAVEAADVVLIRNSLLDVIAAMKLSKDTVRRIRQNFVAATMYNLIGIPIAAGALMPIGVVFMPWMASVAMAASSICVVCLSLLLKLWKKPNEDQLANQEFKNHLECLKYGDMEVGVNLGKDIILPKRKPRRSFRSSISSLWSSMEISKKKPNVSDRIALLENFKND
Sbjct:    1 MDEEIYHFEILIKEVNDKNQLKIIEDFFQFNDNIKTVVIDYEKNLVRICCHNDNCTYLTLCEAIENLGFLINKNKETDNTKELFKCHMRIQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMGFDAEIFQFKEHTKDIIEVMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKLAPKKTNKYNDHVGESIKKWKHSFLISLIFGVPTMIVMMVFMYGFSHRMQVIHLKNGINVTVMVSNAPILFPGLSLENLLLFLFSSPVQFYGARYFYVQAYKSIKHGSANMDVLVVMATSVSYIYSFIVILVSMILRQDSSPQTFFETTPMLIVFLSLGRWLEHIAKGKTSEALSKLLSLQAFEATIIVNDNQERKISVDLVKKGDLVKVLPGEKIPIDGRVVSGKSRCDESLITGESMSVEKIPGSDVIGGTLNISGMLIIRATLVGEDSALNQIVKLVEEAQTSKAPIQELADKVAGLFVPGVIICSMFTLLIWIAIGYTNPNLLPGHSSINTDNTELIWKYAFQLAITVLSVACPCSLGLATPTAVMVGTGVGAINGILIKGGVPLEKMHQLDVIVFDKTGTITTGKPSVTNFVMCVENVTSQIRNCILLMLGAAESSSEHPIGKAILQYVRETCDINEMPQVVHSKSVSGFGLECSLKLQSDMFVPDSEIDNVLVKINDFQENNLTENLKETSVKWRKINEPVEVVLYLGNRNMMKENHISIPDKLDELMSRDEDNGRTVVLMAIDKVLLAMISIADQVKKEAALVVYTLEKMGVEVFLLTGDNHKTATAIAKEIGIRNVFAEVLPSHKVAKIQQIQNMSKYKRSWLFSCCSKPSKLTNVAMVGDGINDSPALAQADVGIAIGTGTDVAVEAADVVLIRNSLLDVIAAMKLSKDTVRRIRQNFVAATMYNLIGIPIAAGALMPIGVVFMPWMASVAMAASSICVVCLSLLLKLWKKPNEDQLANQEFKNHLECLKYGDMEVGVNLGKDIILPKRKPRRSFRSSISSLWSSMEISKKKPNVSDRIALLENFKND 1083

[Close]

BLAST of Copper-transporting ATPase 1 vs. Planmine SMEST
Match: SMESG000039812.1 (SMESG000039812.1)

HSP 1 Score: 1041.57 bits (2692), Expect = 0.000e+0
Identity = 571/1016 (56.20%), Postives = 754/1016 (74.21%), Query Frame = 1

Query:  235 EAIENLGFLI-------NKNKETD----NTKELFKCHMRIQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMGFDAEIFQFKEHTKDIIEVMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKLAP--KKTNKYNDHVGESIKKWKHSFLISLIFGVPTMIVMMVFMYGFSHRMQVIHLKNGINVTVMVSNAPIXXXXXXXXXXXXXXXXXPVQFYGARYFYVQAYKSIKHGSANMDVLVVMATSVSYIYSFIVILVSMILRQDSSPQTFFETTPMLIVFLSLGRWLEHIAKGKTSEALSKLLSLQAFEATIIVNDNQERKISXXXXXXXXXXXXXPGEKIPIDGRVVSGKSRCDESLITGESMSVEKIPGSDVIGGTLNISGMLIIRATLVGEDSALNQIVKLVEEAQTSKAPIQELADKVAGLFVPGVIICSMFTLLIWIAIGYTNPNLLPGHSSINTDNTELIWKYAFQLAITVLSVACPCSLGLATPTAVMVGTGVGAINGILIKGGVPLEKMHQLDVIVFDKTGTITTGKPSVTNFVMCVENVTSQIRNCILLMLGAAESSSEHPIGKAILQYVRETCDINEMPQVVHSKSVSGFGLECSLKLQSDMFVPDSEIDNV---LVKINDFQE--NNLTENLK-----ETSVKWRKINEPVE------------VVLYLGNRNMMKENHISIPDKLDELMSRDEDNGRTVVLMAIDKVLLAMISIADQVKKEAALVVYTLEKMGVEVFLLTGDNHKTATAIAKEIGIRNVFAEVLPSHKVAKIQQIQNMSKYKRSWLFSCCSKPSKLTNVAMVGDGINDSPALAQADVGIAIGTGTDVAVEAADVVLIRNSLLDVIAAMKLSKDTVRRIRQNFVAATMYNLIGIPIAAGALMPIGVVFMPWMASVAMAASSICVVCXXXXXXXXXXPNEDQLANQEFKNHLECLKYGDMEVGVNLGKDIILP 3177
            E IE+LG+L        N  +++     N +   KC++RI GMTCSSCV+ +E+ +LK++GVKS L+ LL+   E+ YD   +M   +++ + ++GF+AE+ +       ++ V+I+GMTCSSCV  IE+ +++++GI S+ V+L+T KGK ++      PRD++DAI +MGFDA L    +  +   DH+ + IK+W+ SF  SLI G+PTM VMM  M+ F      I  +NG N T+M S  P++  GLS +NL+LF+ ++PVQFYGARYFY+QAY S+KH + NMDVLVVMATS+SYIYS IVI++SM  R+++SP+TFFET+PMLIVFLSLGRWLEHIAKGKTSEAL+KL+SLQA EAT+   +N+ERKI ++LV++ DL+K+LPGEKIP+DG+VV+G S CDESLITGESM +EK  GSDVIGG++N SGMLI++AT VG DSAL QIVKLVEEAQTSKAPIQ+LAD++AG+FVP V+IC++ TL+IW+ +G++ P +LP + +     TE+ W++AFQLAITVLS+ACPCSLGLATPTAVMVGTGVGA+NGILIKGG PLE +H+L+VIVFDKTGTIT G PSVT F++ + N   +  + +L +L AAES+SEHPIGKAI+ + +       +P+V+ S +VSG GL C L L      P +E+      L+ I    E  N L +N+      +  + ++ +  PV             V + +GNRN M+ N I + D++DELMS DE+ GRTV+LMAID  L+AMIS+ADQVK+EAAL VYTL+KM +EV+L+TGDN KTATAIA+++GI  VFAEVLPSHKVAK+QQ+QN ++       S  SK  +   VAMVGDGINDSPALAQ+DVGIAIGTGTDVAVEAADVVLIRNSLLDVIAA++LSK TV+RIRQNF+AAT+YNL+GIPIAAG LMPIG+  MPWMAS AMAASS+ VV LSLLLKLWKKP+E++L   E+ N ++     + ++ V  G D++ P
Sbjct:  310 EEIESLGYLTELPKQNWNSTRQSSAVSLNEESRSKCYLRITGMTCSSCVNKVESHLLKVEGVKSVLVALLAMKCEIIYDSAYVMPFQLSNRVKELGFNAEVIENGNEGIGVVNVLIRGMTCSSCVNHIENHISKIKGIASINVSLSTSKGKVEYFISECGPRDVIDAINDMGFDASLCDHLESNHAAADHINQMIKQWRSSFFFSLICGIPTMFVMMFTMFNFKMVKHTIIHENGSNRTIMRSTVPMVCSGLSADNLILFVLATPVQFYGARYFYIQAYLSLKHKTTNMDVLVVMATSISYIYSVIVIVISMAFRRNTSPKTFFETSPMLIVFLSLGRWLEHIAKGKTSEALTKLMSLQAVEATLYTPENKERKIPINLVQRNDLIKILPGEKIPVDGKVVTGTSTCDESLITGESMPIEKTHGSDVIGGSINKSGMLIVKATHVGSDSALAQIVKLVEEAQTSKAPIQQLADRIAGMFVPSVLICAIITLIIWVIVGFSKPEILPKYVN-ELSVTEITWEHAFQLAITVLSIACPCSLGLATPTAVMVGTGVGAVNGILIKGGEPLENIHKLNVIVFDKTGTITNGSPSVTRFLVLIGNGVREHIDKLLKILAAAESASEHPIGKAIITFSKARISNENLPEVLESSAVSGCGLGCKLNLD-----PKTEVTKFVKNLINIESPSEETNILGQNMNININDDIRITYKDVIFPVRQHMAWTSDLCQTVTVIIGNRNWMQRNGILVDDEVDELMSEDENLGRTVILMAIDNELIAMISVADQVKREAALAVYTLKKMNIEVYLMTGDNSKTATAIARQVGIHYVFAEVLPSHKVAKVQQLQNTNR-------SLTSK--RKMKVAMVGDGINDSPALAQSDVGIAIGTGTDVAVEAADVVLIRNSLLDVIAAIQLSKATVKRIRQNFIAATLYNLLGIPIAAGVLMPIGIEMMPWMASAAMAASSVSVVTLSLLLKLWKKPSEEKLITPEYINFIQSSGLSESQIIVRRGIDLMTP 1310

HSP 2 Score: 75.0998 bits (183), Expect = 3.272e-13
Identity = 43/143 (30.07%), Postives = 71/143 (49.65%), Query Frame = 1

Query:  343 CVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMGFDAEI-------------FQFKEHTKDIIEVMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKL 732
            C+  IEN +  L GV    +NL+  IG + YD        I + I  +G+  E+                 E ++    + I GMTCSSCV  +ES L +++G+ SV VAL   K +  +D   + P  + + ++E+GF+A++
Sbjct:  268 CIFKIENHMRALPGVDKCSVNLIEEIGMIDYDSGKWNVQKIREEIESLGYLTELPKQNWNSTRQSSAVSLNEESRSKCYLRITGMTCSSCVNKVESHLLKVEGVKSVLVALLAMKCEIIYDSAYVMPFQLSNRVKELGFNAEV 410

HSP 3 Score: 60.077 bits (144), Expect = 1.015e-8
Identity = 45/185 (24.32%), Postives = 81/185 (43.78%), Query Frame = 1

Query:  313 MRIQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMGFDAEIF-----------------QFKEHTKDII------EVMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKLAPKKTNKYNDHVGESIKKWKHS 798
            +R+ GMTC SCV  IE+ V K +G+ S  + L  +      D  L    D+ + INDMGF++E+                  +++E   + I       ++I+ +    C++ IE+ +  + G+    V L  E G   +D    + + I + IE +G+  +L  +  N        S+ +   S
Sbjct:  160 VRVNGMTCQSCVDNIESTVGKKQGIISIKVFLEKSEAHALVDASL-AGPDVEEMINDMGFNSEMILEIFNDSCAGKPNNVSQKYEELKSNTIYPILSTTIVIKALKSIFCIFKIENHMRALPGVDKCSVNLIEEIGMIDYDSGKWNVQKIREEIESLGYLTELPKQNWNSTRQSSAVSLNEESRS 343

HSP 4 Score: 60.077 bits (144), Expect = 1.308e-8
Identity = 26/70 (37.14%), Postives = 41/70 (58.57%), Query Frame = 1

Query:  295 ELFKCHMRIQGMTCSSCVHTIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMGFDAEI 504
            +L    M++ GMTC SCV  IE  ++K  GV   +++LL     V +D D+    DI++ I++MGFD  +
Sbjct:    2 KLGSARMKVDGMTCMSCVRNIEENLMKFTGVCGIMVSLLQAEATVIFDADIATVEDISNKIDEMGFDVTV 71

HSP 5 Score: 54.299 bits (129), Expect = 5.985e-7
Identity = 28/82 (34.15%), Postives = 42/82 (51.22%), Query Frame = 1

Query:  547 IQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKGKFKFDPQIISPRDILDAIEEMGFDAKLAPKKTNKYNDHVGESIKKWK 792
            + GMTC SCV  IE  L +  G+  + V+L   +    FD  I +  DI + I+EMGFD  +   + +   D V  S  K++
Sbjct:   10 VDGMTCMSCVRNIEENLMKFTGVCGIMVSLLQAEATVIFDADIATVEDISNKIDEMGFDVTVKSSEVSNVKDKVVRSRIKFE 91

[Close]

BLAST of Copper-transporting ATPase 1 vs. Planmine SMEST
Match: SMESG000014734.1 (SMESG000014734.1)

HSP 1 Score: 79.7221 bits (195), Expect = 1.179e-14
Identity = 70/236 (29.66%), Postives = 110/236 (46.61%), Query Frame = 1

Query: 2437 DKVLLAMISIADQVKKEAALVVYTLEKMGVEVFLLTGDNHKTATAIAKEIGI----------------------------RNVFAEVLPSHKVAKIQQIQNMSKYKR-SWLFSCCSKPSKLTNVAMVGDGINDSPALAQADVGIAIG-TGTDVAVEAADVVLIRNSLLDVIAAMKLSKDTVRRIRQNFVAATMYNLIGIPIA-AGALM----PIGVVFMPW-------MASVAMAA 3018
            D   LA++ I D V+ E    +   +K G+ V ++TGDN  TA +IA + GI                            +++  +V PS +V      Q+  KY   S + +    P++   VA+ GDG ND PAL +ADVG A+G  GTDVA EA+D++L  ++   ++ A+   ++    I +        NL+ I +A  GA      P+  V M W       +AS+A+A 
Sbjct:  666 DLTCLAIVGIEDPVRPEVPNAIMKCQKAGITVRMVTGDNVNTARSIATKCGILKPGDDFLVLEGKEFNQRIRSPKTGEVRQDLIDKVWPSLRVLARSSPQD--KYTLVSGIIASHLNPTREV-VAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLTVNLVAIVVAFVGACFITDSPLKAVQMLWVNLIMDTLASLALAT 898

[Close]

BLAST of Copper-transporting ATPase 1 vs. Planmine SMEST
Match: SMESG000014734.1 (SMESG000014734.1)

HSP 1 Score: 79.337 bits (194), Expect = 1.334e-14
Identity = 70/236 (29.66%), Postives = 110/236 (46.61%), Query Frame = 1

Query: 2437 DKVLLAMISIADQVKKEAALVVYTLEKMGVEVFLLTGDNHKTATAIAKEIGI----------------------------RNVFAEVLPSHKVAKIQQIQNMSKYKR-SWLFSCCSKPSKLTNVAMVGDGINDSPALAQADVGIAIG-TGTDVAVEAADVVLIRNSLLDVIAAMKLSKDTVRRIRQNFVAATMYNLIGIPIA-AGALM----PIGVVFMPW-------MASVAMAA 3018
            D   LA++ I D V+ E    +   +K G+ V ++TGDN  TA +IA + GI                            +++  +V PS +V      Q+  KY   S + +    P++   VA+ GDG ND PAL +ADVG A+G  GTDVA EA+D++L  ++   ++ A+   ++    I +        NL+ I +A  GA      P+  V M W       +AS+A+A 
Sbjct:  666 DLTCLAIVGIEDPVRPEVPNAIMKCQKAGITVRMVTGDNVNTARSIATKCGILKPGDDFLVLEGKEFNQRIRSPKTGEVRQDLIDKVWPSLRVLARSSPQD--KYTLVSGIIASHLNPTREV-VAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLTVNLVAIVVAFVGACFITDSPLKAVQMLWVNLIMDTLASLALAT 898

[Close]

BLAST of Copper-transporting ATPase 1 vs. Planmine SMEST
Match: SMESG000014734.1 (SMESG000014734.1)

HSP 1 Score: 79.337 bits (194), Expect = 1.342e-14
Identity = 70/236 (29.66%), Postives = 110/236 (46.61%), Query Frame = 1

Query: 2437 DKVLLAMISIADQVKKEAALVVYTLEKMGVEVFLLTGDNHKTATAIAKEIGI----------------------------RNVFAEVLPSHKVAKIQQIQNMSKYKR-SWLFSCCSKPSKLTNVAMVGDGINDSPALAQADVGIAIG-TGTDVAVEAADVVLIRNSLLDVIAAMKLSKDTVRRIRQNFVAATMYNLIGIPIA-AGALM----PIGVVFMPW-------MASVAMAA 3018
            D   LA++ I D V+ E    +   +K G+ V ++TGDN  TA +IA + GI                            +++  +V PS +V      Q+  KY   S + +    P++   VA+ GDG ND PAL +ADVG A+G  GTDVA EA+D++L  ++   ++ A+   ++    I +        NL+ I +A  GA      P+  V M W       +AS+A+A 
Sbjct:  672 DLTCLAIVGIEDPVRPEVPNAIMKCQKAGITVRMVTGDNVNTARSIATKCGILKPGDDFLVLEGKEFNQRIRSPKTGEVRQDLIDKVWPSLRVLARSSPQD--KYTLVSGIIASHLNPTREV-VAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLTVNLVAIVVAFVGACFITDSPLKAVQMLWVNLIMDTLASLALAT 904

The following BLAST results are available for this feature:

BLAST of Copper-transporting ATPase 1 vs. Ensembl Human
BLAST of Copper-transporting ATPase 1 vs. Ensembl Celegans
BLAST of Copper-transporting ATPase 1 vs. Ensembl Fly
BLAST of Copper-transporting ATPase 1 vs. Ensembl Zebrafish
BLAST of Copper-transporting ATPase 1 vs. Ensembl Xenopus
BLAST of Copper-transporting ATPase 1 vs. Ensembl Mouse
BLAST of Copper-transporting ATPase 1 vs. UniProt/SwissProt
BLAST of Copper-transporting ATPase 1 vs. TrEMBL
BLAST of Copper-transporting ATPase 1 vs. Ensembl Cavefish
BLAST of Copper-transporting ATPase 1 vs. Ensembl Sea Lamprey
BLAST of Copper-transporting ATPase 1 vs. Ensembl Yeast
BLAST of Copper-transporting ATPase 1 vs. Ensembl Nematostella
BLAST of Copper-transporting ATPase 1 vs. Ensembl Medaka
BLAST of Copper-transporting ATPase 1 vs. Planmine SMEST

BLAST of Copper-transporting ATPase 1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ATP7B	3.271e-24	48.34	ATPase copper transporting beta [Source:HGNC Symbo...	[more]
ATP7A	1.678e-19	49.30	ATPase copper transporting alpha [Source:HGNC Symb...	[more]
ATP7B	3.914e-24	48.34	ATPase copper transporting beta [Source:HGNC Symbo...	[more]
ATP7B	3.716e-24	45.97	ATPase copper transporting beta [Source:HGNC Symbo...	[more]
ATP7B	6.841e-31	43.24	ATPase copper transporting beta [Source:HGNC Symbo...	[more]

BLAST of Copper-transporting ATPase 1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
cua-1	2.141e-11	46.19	CU (Copper) ATPase [Source:UniProtKB/TrEMBL;Acc:G...	[more]
cua-1	1.171e-16	46.19	CU (Copper) ATPase [Source:UniProtKB/TrEMBL;Acc:G...	[more]
catp-1	2.100e-14	30.86	Cation transporting ATPase [Source:UniProtKB/TrEM...	[more]
catp-1	3.041e-14	30.86	Cation transporting ATPase [Source:UniProtKB/TrEM...	[more]
sca-1	3.086e-14	23.30	Calcium-transporting ATPase [Source:UniProtKB/TrE...	[more]

BLAST of Copper-transporting ATPase 1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ATP7	1.355e-15	45.51	gene:FBgn0030343 transcript:FBtr0334454	[more]
ATP7	1.355e-15	45.51	gene:FBgn0030343 transcript:FBtr0273257	[more]
SPoCk	6.088e-14	33.53	gene:FBgn0052451 transcript:FBtr0078531	[more]
SPoCk	6.470e-14	33.53	gene:FBgn0052451 transcript:FBtr0306600	[more]
SPoCk	6.470e-14	33.53	gene:FBgn0052451 transcript:FBtr0302134	[more]

BLAST of Copper-transporting ATPase 1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
atp7a	4.911e-20	48.82	ATPase copper transporting alpha [Source:ZFIN;Acc:...	[more]
atp7b	6.174e-16	48.46	ATPase copper transporting beta [Source:ZFIN;Acc:Z...	[more]
atp7a	4.769e-20	47.89	ATPase copper transporting alpha [Source:ZFIN;Acc:...	[more]
atp7b	2.475e-15	47.96	ATPase copper transporting beta [Source:ZFIN;Acc:Z...	[more]
atp7a	5.324e-20	46.88	ATPase copper transporting alpha [Source:ZFIN;Acc:...	[more]

BLAST of Copper-transporting ATPase 1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
dhx34	9.808e-16	47.81	DEAH-box helicase 34 [Source:Xenbase;Acc:XB-GENE-1...	[more]
dhx34	4.303e-15	48.24	DEAH-box helicase 34 [Source:Xenbase;Acc:XB-GENE-1...	[more]
dhx34	4.729e-15	48.24	DEAH-box helicase 34 [Source:Xenbase;Acc:XB-GENE-1...	[more]
dhx34	1.112e-18	47.83	DEAH-box helicase 34 [Source:Xenbase;Acc:XB-GENE-1...	[more]
dhx34	1.591e-14	47.64	DEAH-box helicase 34 [Source:Xenbase;Acc:XB-GENE-1...	[more]

BLAST of Copper-transporting ATPase 1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Atp7b	2.437e-21	49.01	ATPase, Cu++ transporting, beta polypeptide [Sourc...	[more]
Atp7a	1.289e-20	47.95	ATPase, Cu++ transporting, alpha polypeptide [Sour...	[more]
Atp7a	1.111e-21	48.00	ATPase, Cu++ transporting, alpha polypeptide [Sour...	[more]
Atp7b	2.898e-21	49.01	ATPase, Cu++ transporting, beta polypeptide [Sourc...	[more]
Atp2a1	4.156e-15	27.46	ATPase, Ca++ transporting, cardiac muscle, fast tw...	[more]

BLAST of Copper-transporting ATPase 1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q64446\|ATP7B_MOUSE	2.027e-20	49.01	Copper-transporting ATPase 2 OS=Mus musculus OX=10...	[more]
sp\|Q64430\|ATP7A_MOUSE	7.772e-21	48.00	Copper-transporting ATPase 1 OS=Mus musculus OX=10...	[more]
sp\|Q64535\|ATP7B_RAT	4.816e-21	49.18	Copper-transporting ATPase 2 OS=Rattus norvegicus ...	[more]
sp\|P35670\|ATP7B_HUMAN	1.571e-23	48.34	Copper-transporting ATPase 2 OS=Homo sapiens OX=96...	[more]
sp\|P70705\|ATP7A_RAT	6.818e-20	47.42	Copper-transporting ATPase 1 OS=Rattus norvegicus ...	[more]

BLAST of Copper-transporting ATPase 1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A2C9KDW4	2.415e-23	52.94	Uncharacterized protein OS=Biomphalaria glabrata O...	[more]
A0A2C9KE23	2.506e-23	52.72	Uncharacterized protein OS=Biomphalaria glabrata O...	[more]
A0A2C9KDZ0	1.126e-22	52.72	Uncharacterized protein OS=Biomphalaria glabrata O...	[more]
A0A2C9KDX7	3.221e-22	52.72	Uncharacterized protein OS=Biomphalaria glabrata O...	[more]
A0A0L8GFT7	6.151e-20	49.81	Uncharacterized protein OS=Octopus bimaculoides OX...	[more]

BLAST of Copper-transporting ATPase 1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
atp7a	5.948e-18	48.62	ATPase copper transporting alpha [Source:NCBI gene...	[more]
atp7b	1.060e-170	51.09	ATPase copper transporting beta [Source:ZFIN;Acc:Z...	[more]
atp2c1	5.968e-15	35.12	ATPase secretory pathway Ca2+ transporting 1 [Sour...	[more]
atp2a1l	1.684e-14	29.07	sarcoplasmic/endoplasmic reticulum calcium ATPase ...	[more]
atp2a1l	1.694e-14	29.07	sarcoplasmic/endoplasmic reticulum calcium ATPase ...	[more]

BLAST of Copper-transporting ATPase 1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5


Match Name	E-value	Identity	Description
atp7b	0.000e+0	44.76	ATPase copper transporting beta [Source:ZFIN;Acc:Z...	[more]
ENSPMAT00000002230.1	2.489e-62	62.57	pep scaffold:Pmarinus_7.0:GL493059:69:4752:-1 gene...	[more]
ENSPMAT00000010051.1	1.779e-13	26.35	pep scaffold:Pmarinus_7.0:GL484878:2955:5956:-1 ge...	[more]
atp2c1	5.835e-12	31.58	ATPase secretory pathway Ca2+ transporting 1 [Sour...	[more]
ENSPMAT00000010373.1	7.456e-12	26.67	pep scaffold:Pmarinus_7.0:GL481096:3909:20014:1 ge...	[more]

BLAST of Copper-transporting ATPase 1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 5


Match Name	E-value	Identity	Description
CCC2	5.598e-132	32.42	Cu(+2)-transporting P-type ATPase; required for ex...	[more]
PCA1	8.978e-74	30.48	Cadmium transporting P-type ATPase; may also have ...	[more]
PMA1	6.743e-23	24.00	Plasma membrane P2-type H+-ATPase; pumps protons o...	[more]
PMA2	4.352e-22	23.61	Plasma membrane H+-ATPase; isoform of Pma1p, invol...	[more]
ENA5	6.994e-16	31.86	Protein with similarity to P-type ATPase sodium pu...	[more]

BLAST of Copper-transporting ATPase 1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5


Match Name	E-value	Identity	Description
EDO47080	1.237e-21	44.92	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO43417	1.732e-55	29.98	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO28080	3.571e-20	23.66	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO35616	1.287e-13	31.15	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO36455	1.347e-12	28.00	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of Copper-transporting ATPase 1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
atp7b	2.816e-24	49.73	copper-transporting ATPase 2 [Source:NCBI gene;Acc...	[more]
atp7a	5.672e-20	50.00	copper-transporting ATPase 1 [Source:NCBI gene;Acc...	[more]
atp7a	4.166e-9	45.24	copper-transporting ATPase 1 [Source:NCBI gene;Acc...	[more]
si:dkey-28b4.8	7.914e-15	23.11	sarcoplasmic/endoplasmic reticulum calcium ATPase ...	[more]
si:dkey-28b4.8	8.007e-15	23.11	sarcoplasmic/endoplasmic reticulum calcium ATPase ...	[more]

BLAST of Copper-transporting ATPase 1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000058134.1	0.000e+0	100.00	SMESG000058134.1	[more]
SMESG000039812.1	3.272e-13	56.20	SMESG000039812.1	[more]
SMESG000014734.1	1.179e-14	29.66	SMESG000014734.1	[more]
SMESG000014734.1	1.334e-14	29.66	SMESG000014734.1	[more]
SMESG000014734.1	1.342e-14	29.66	SMESG000014734.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30008855 ID=SMED30008855|Name=Copper-transporting ATPase 1|organism=Schmidtea mediterranea sexual|type=transcript|length=3467bp
CCAAAAGTTTAATTATTTTTCCATTATTGAACAATCTTGGAAGTATACTT
TATGGATGAAGAAATATATCATTTTGAAATTCTCATTAAAGAAGTTAATG
ATAAAAACCAATTAAAAATAATTGAGGATTTTTTTCAATTTAATGATAAT
ATTAAGACAGTTGTGATTGATTATGAAAAAAATTTAGTGAGAATTTGTTG
TCACAATGACAATTGTACATATTTGACACTGTGCGAAGCCATTGAAAATT
TGGGTTTTTTGATCAACAAAAATAAAGAAACTGATAATACGAAAGAGCTA
TTTAAATGTCATATGAGAATTCAAGGTATGACGTGCTCATCATGTGTCCA
TACAATCGAAAATCAAGTACTAAAATTGAAAGGAGTAAAGTCGGCTTTAA
TTAATTTGTTATCTACCATTGGTGAAGTTACCTATGATCCAGACCTGATA
ATGGCATCTGACATTGCCGATACAATCAATGATATGGGCTTTGATGCTGA
AATATTCCAATTCAAAGAGCATACAAAAGATATAATAGAAGTTATGATTC
AAGGTATGACATGTTCAAGTTGTGTCTACACAATAGAAAGCAAATTAGCT
CAAATGCAGGGAATACTATCCGTAAAGGTTGCTCTGACAACTGAAAAAGG
AAAATTTAAATTCGATCCCCAAATTATTAGCCCTAGAGATATACTTGATG
CGATTGAAGAAATGGGGTTTGATGCCAAATTAGCGCCGAAGAAAACCAAC
AAATACAACGACCATGTGGGAGAATCAATTAAAAAATGGAAACACTCTTT
TTTGATTTCTTTGATTTTTGGCGTCCCAACTATGATAGTGATGATGGTAT
TTATGTACGGTTTTAGTCACAGAATGCAAGTAATACATTTAAAAAACGGT
ATTAATGTCACTGTAATGGTATCTAATGCACCGATTCTTTTTCCTGGCTT
GTCTTTGGAAAATTTACTTTTATTCCTGTTTTCTTCACCTGTTCAATTTT
ATGGAGCCAGATATTTCTATGTTCAAGCTTATAAATCGATAAAACATGGT
TCTGCAAACATGGATGTGCTTGTAGTCATGGCAACCAGTGTGTCTTACAT
ATATTCCTTTATCGTTATTCTTGTCAGTATGATTTTGAGACAAGATTCAA
GTCCACAGACCTTCTTTGAAACAACTCCAATGTTGATTGTGTTTCTTTCT
CTTGGCAGATGGTTAGAACATATAGCTAAAGGTAAGACATCAGAAGCACT
AAGTAAACTTTTGTCCCTTCAAGCATTTGAAGCGACAATTATAGTGAACG
ATAATCAAGAAAGAAAAATCTCAGTTGATCTAGTAAAAAAGGGAGATCTT
GTCAAGGTGCTTCCCGGAGAAAAGATTCCTATTGATGGTAGAGTGGTATC
TGGTAAATCTCGATGTGATGAATCCCTCATCACAGGTGAATCAATGTCAG
TAGAAAAGATTCCCGGCTCTGATGTTATTGGAGGAACTTTAAATATATCT
GGTATGCTTATAATTAGAGCCACTCTTGTCGGCGAAGATTCTGCCCTCAA
TCAAATCGTAAAACTTGTTGAAGAAGCTCAAACGTCAAAAGCTCCTATTC
AAGAATTGGCGGATAAAGTTGCCGGTTTATTTGTTCCCGGTGTAATAATA
TGTTCTATGTTCACATTACTAATTTGGATTGCCATAGGATACACAAATCC
TAATTTGCTCCCAGGACACTCTTCAATTAATACAGATAATACGGAATTGA
TATGGAAATATGCATTCCAATTAGCTATTACAGTGTTAAGTGTAGCATGT
CCATGTTCTCTAGGCCTTGCTACACCGACTGCTGTAATGGTCGGAACCGG
CGTGGGTGCTATTAATGGCATACTAATTAAGGGAGGAGTTCCTTTGGAGA
AGATGCATCAATTAGATGTAATCGTCTTCGACAAAACTGGAACGATAACT
ACAGGAAAACCTTCAGTTACGAATTTTGTAATGTGTGTTGAAAATGTTAC
CAGTCAAATTCGGAATTGCATTCTTCTAATGCTTGGAGCTGCAGAATCCT
CATCAGAACATCCAATTGGCAAAGCTATATTGCAGTATGTTCGAGAGACA
TGCGATATTAATGAAATGCCTCAGGTGGTCCATTCAAAATCTGTTTCGGG
ATTCGGATTAGAATGTTCATTGAAGCTACAATCAGATATGTTCGTTCCAG
ATTCAGAGATTGACAATGTTTTAGTCAAAATAAATGACTTTCAAGAAAAT
AATTTGACAGAGAACTTGAAAGAGACTTCAGTCAAATGGAGAAAAATCAA
TGAACCAGTGGAAGTGGTTCTATACTTAGGAAATCGAAATATGATGAAAG
AGAACCATATTTCAATTCCAGATAAACTGGATGAGTTAATGTCTAGAGAT
GAAGATAATGGTCGTACAGTAGTATTGATGGCTATCGATAAGGTATTATT
GGCGATGATTTCAATTGCTGATCAAGTTAAAAAAGAAGCAGCTTTAGTTG
TATATACATTAGAGAAAATGGGAGTAGAGGTGTTCCTACTTACAGGAGAT
AATCACAAAACAGCTACTGCCATCGCAAAAGAGATTGGAATTCGGAATGT
ATTTGCTGAGGTACTTCCTTCGCATAAAGTTGCTAAAATTCAACAAATTC
AAAACATGTCGAAATATAAACGATCATGGTTGTTCAGTTGTTGTTCAAAG
CCCTCAAAGTTAACAAATGTAGCTATGGTTGGAGATGGAATCAATGACAG
TCCGGCACTTGCACAAGCTGATGTTGGGATAGCAATTGGAACTGGAACAG
ATGTGGCAGTTGAAGCGGCTGACGTAGTTTTGATTCGTAATTCTTTACTT
GATGTTATTGCTGCCATGAAACTAAGCAAAGACACCGTCAGAAGAATCAG
GCAGAATTTTGTTGCAGCTACTATGTACAATCTTATTGGTATTCCAATTG
CGGCAGGTGCCCTTATGCCGATTGGGGTGGTTTTTATGCCTTGGATGGCA
TCAGTAGCCATGGCTGCAAGCTCAATCTGCGTCGTGTGTTTAAGTCTCCT
TTTGAAGTTATGGAAAAAACCAAATGAAGATCAATTGGCTAATCAGGAAT
TCAAAAACCATTTGGAGTGTTTGAAATATGGAGATATGGAAGTTGGAGTA
AATTTAGGCAAAGACATTATTTTACCCAAACGAAAACCCAGACGATCTTT
CAGAAGCAGTATCAGCAGTTTGTGGTCAAGCATGGAAATATCAAAAAAGA
AACCAAATGTTTCAGATCGAATCGCGTTGCTTGAGAATTTTAAAAACGAT
TAGAATACTTCTAGAACACATCACAAGTTTTGGCATAACTTTTTAACTTT
CCCTTTTCCCCACTCACATATTTTAGCATTTTTAGCATTGTTTTAATGAA
TTTATTATCATTTTACTGCAAAATGGCCGATTTGTCAATGTGATCCATAA
TAATAGTTTTTGATCAG

protein sequence of SMED30008855-orf-1

>SMED30008855-orf-1 ID=SMED30008855-orf-1|Name=SMED30008855-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=1084bp
MDEEIYHFEILIKEVNDKNQLKIIEDFFQFNDNIKTVVIDYEKNLVRICC
HNDNCTYLTLCEAIENLGFLINKNKETDNTKELFKCHMRIQGMTCSSCVH
TIENQVLKLKGVKSALINLLSTIGEVTYDPDLIMASDIADTINDMGFDAE
IFQFKEHTKDIIEVMIQGMTCSSCVYTIESKLAQMQGILSVKVALTTEKG
KFKFDPQIISPRDILDAIEEMGFDAKLAPKKTNKYNDHVGESIKKWKHSF
LISLIFGVPTMIVMMVFMYGFSHRMQVIHLKNGINVTVMVSNAPILFPGL
SLENLLLFLFSSPVQFYGARYFYVQAYKSIKHGSANMDVLVVMATSVSYI
YSFIVILVSMILRQDSSPQTFFETTPMLIVFLSLGRWLEHIAKGKTSEAL
SKLLSLQAFEATIIVNDNQERKISVDLVKKGDLVKVLPGEKIPIDGRVVS
GKSRCDESLITGESMSVEKIPGSDVIGGTLNISGMLIIRATLVGEDSALN
QIVKLVEEAQTSKAPIQELADKVAGLFVPGVIICSMFTLLIWIAIGYTNP
NLLPGHSSINTDNTELIWKYAFQLAITVLSVACPCSLGLATPTAVMVGTG
VGAINGILIKGGVPLEKMHQLDVIVFDKTGTITTGKPSVTNFVMCVENVT
SQIRNCILLMLGAAESSSEHPIGKAILQYVRETCDINEMPQVVHSKSVSG
FGLECSLKLQSDMFVPDSEIDNVLVKINDFQENNLTENLKETSVKWRKIN
EPVEVVLYLGNRNMMKENHISIPDKLDELMSRDEDNGRTVVLMAIDKVLL
AMISIADQVKKEAALVVYTLEKMGVEVFLLTGDNHKTATAIAKEIGIRNV
FAEVLPSHKVAKIQQIQNMSKYKRSWLFSCCSKPSKLTNVAMVGDGINDS
PALAQADVGIAIGTGTDVAVEAADVVLIRNSLLDVIAAMKLSKDTVRRIR
QNFVAATMYNLIGIPIAAGALMPIGVVFMPWMASVAMAASSICVVCLSLL
LKLWKKPNEDQLANQEFKNHLECLKYGDMEVGVNLGKDIILPKRKPRRSF
RSSISSLWSSMEISKKKPNVSDRIALLENFKND*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **biological process**
Term	Definition
GO:0098655	cation transmembrane transport
GO:0030001	metal ion transport
GO:0006810	transport
GO:0006811	ion transport
GO:0006812	cation transport
GO:0006825	copper ion transport
GO:0006878	cellular copper ion homeostasis
GO:0006882	cellular zinc ion homeostasis
GO:0007595	lactation
GO:0015677	copper ion import
GO:0015680	intracellular copper ion transport
GO:0035434	copper ion transmembrane transport
GO:0046688	response to copper ion
GO:0051208	sequestering of calcium ion
GO:0060003	copper ion export
GO:0099132	ATP hydrolysis coupled cation transmembrane transport

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000026	gut
PLANA:0000044	cephalic ganglia
PLANA:0000099	neuron
PLANA:0000421	tail
PLANA:0002142	parenchyma

Vocabulary: **INTERPRO**
Term	Definition
IPR027256	P-typ_ATPase_IB
IPR006122	HMA_Cu_ion-bd
IPR001757	P_typ_ATPase
IPR036412	HAD-like_sf
IPR023298	ATPase_P-typ_TM_dom_sf
IPR036163	HMA_dom_sf
IPR008250	ATPase_P-typ_transduc_dom_A_sf
IPR006121	HMA_dom
IPR023214	HAD_sf
IPR023299	ATPase_P-typ_cyto_dom_N
IPR017969	Heavy-metal-associated_CS
IPR018303	ATPase_P-typ_P_site

Vocabulary: **molecular function**
Term	Definition
GO:0046872	metal ion binding
GO:0000166	nucleotide binding
GO:0004008	copper-exporting ATPase activity
GO:0005375	copper ion transmembrane transporter activity
GO:0005507	copper ion binding
GO:0005524	ATP binding
GO:0016787	hydrolase activity
GO:0019829	cation-transporting ATPase activity
GO:0043682	copper-transporting ATPase activity

Vocabulary: **cellular component**
Term	Definition
GO:0005768	endosome
GO:0005770	late endosome
GO:0005794	Golgi apparatus
GO:0005802	trans-Golgi network
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0016323	basolateral plasma membrane
GO:0031410	cytoplasmic vesicle
GO:0032588	trans-Golgi network membrane
GO:0048471	perinuclear region of cytoplasm

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
None	No IPR available	PRINTS	PR00119	CATATPASE	coord: 456..470 score: 52.14 coord: 625..639 score: 53.89 coord: 893..912 score: 64.82 coord: 823..833 score: 48.26 coord: 916..928 score: 54.2
None	No IPR available	PRINTS	PR00942	CUATPASEI	coord: 111..134 score: 39.58 coord: 140..160 score: 20.95 coord: 184..205 score: 43.64 coord: 300..320 score: 48.57 coord: 250..271 score: 40.91 coord: 320..345 score: 71.92 coord: 85..110 score: 44.62
None	No IPR available	PFAM	PF00122	E1-E2_ATPase	coord: 407..602 e-value: 7.9E-47 score: 159.1
None	No IPR available	PFAM	PF00702	Hydrolase	coord: 622..907 e-value: 4.6E-44 score: 151.2
None	No IPR available	GENE3D	G3DSA:2.70.150.20		coord: 393..510 e-value: 3.0E-41 score: 142.1
None	No IPR available	GENE3D	G3DSA:3.30.70.100		coord: 159..230 e-value: 2.7E-21 score: 77.7
None	No IPR available	GENE3D	G3DSA:3.30.70.100		coord: 80..151 e-value: 2.7E-21 score: 77.7
None	No IPR available	SFLD	SFLDS00003	Haloacid_Dehalogenase	coord: 607..943 e-value: 0.0 score: 176.4
None	No IPR available	SFLD	SFLDF00027	p-type_atpase	coord: 607..943 e-value: 0.0 score: 176.4
None	No IPR available	PANTHER	PTHR43520:SF9	COPPER-TRANSPORTING ATPASE 2	coord: 70..1024
None	No IPR available	PANTHER	PTHR43520	FAMILY NOT NAMED	coord: 70..1024
None	No IPR available	CDD	cd02094	P-type_ATPase_Cu-like	coord: 248..996 e-value: 0.0 score: 867.948
None	No IPR available	TMHMM	TMhelix		coord: 979..1001
None	No IPR available	TMHMM	TMhelix		coord: 587..609
None	No IPR available	TMHMM	TMhelix		coord: 953..975
None	No IPR available	TMHMM	TMhelix		coord: 371..388
None	No IPR available	TMHMM	TMhelix		coord: 523..545
None	No IPR available	TMHMM	TMhelix		coord: 296..318
None	No IPR available	TMHMM	TMhelix		coord: 339..361
None	No IPR available	TMHMM	TMhelix		coord: 249..271
IPR027256	P-type ATPase, subfamily IB	TIGRFAM	TIGR01525	TIGR01525	coord: 337..1001 e-value: 2.2E-188 score: 625.6
IPR006122	Heavy metal-associated domain, copper ion-binding	TIGRFAM	TIGR00003	TIGR00003	coord: 86..149 e-value: 3.2E-11 score: 41.3 coord: 163..225 e-value: 1.2E-11 score: 42.7
IPR001757	P-type ATPase	TIGRFAM	TIGR01494	TIGR01494	coord: 378..547 e-value: 1.1E-20 score: 71.5 coord: 778..972 e-value: 9.3E-34 score: 114.6
IPR006121	Heavy metal-associated domain, HMA	PFAM	PF00403	HMA	coord: 89..148 e-value: 4.4E-11 score: 43.1 coord: 164..224 e-value: 1.3E-12 score: 47.9
IPR006121	Heavy metal-associated domain, HMA	PROSITE	PS50846	HMA_2	coord: 161..227 score: 21.8
IPR006121	Heavy metal-associated domain, HMA	PROSITE	PS50846	HMA_2	coord: 85..151 score: 20.642
IPR006121	Heavy metal-associated domain, HMA	CDD	cd00371	HMA	coord: 163..226 e-value: 4.84722E-16 score: 71.4829
IPR006121	Heavy metal-associated domain, HMA	CDD	cd00371	HMA	coord: 88..150 e-value: 1.16666E-14 score: 67.2457
IPR018303	P-type ATPase, phosphorylation site	PROSITE	PS00154	ATPASE_E1_E2	coord: 627..633
IPR017969	Heavy-metal-associated, conserved site	PROSITE	PS01047	HMA_1	coord: 90..119
IPR017969	Heavy-metal-associated, conserved site	PROSITE	PS01047	HMA_1	coord: 166..195
IPR008250	P-type ATPase, A domain superfamily	SUPERFAMILY	SSF81653	Calcium ATPase, transduction domain A	coord: 413..506
IPR036412	HAD-like superfamily	SUPERFAMILY	SSF56784	HAD-like	coord: 623..996
IPR023298	P-type ATPase, transmembrane domain superfamily	SUPERFAMILY	SSF81665	Calcium ATPase, transmembrane domain M	coord: 378..610
IPR036163	Heavy metal-associated domain superfamily	SUPERFAMILY	SSF55008	HMA, heavy metal-associated domain	coord: 81..155
IPR036163	Heavy metal-associated domain superfamily	SUPERFAMILY	SSF55008	HMA, heavy metal-associated domain	coord: 162..228
IPR023299	P-type ATPase, cytoplasmic domain N	SUPERFAMILY	SSF81660	Metal cation-transporting ATPase, ATP-binding domain N	coord: 657..810