Slc15a-8

Overview
NameSlc15a-8
Smed IDSMED30008828
Length (bp)1713
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Slc15a-8 (SMED30008828) t-SNE clustered cells

Violin plots show distribution of expression levels for Slc15a-8 (SMED30008828) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Slc15a-8 (SMED30008828) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Slc15a-8 (SMED30008828) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30008828

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 6

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
intestinal phagocyteSMED30008828SMESG000009967.1 PL08006B2G09ncbi_smed_estsPMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
cephalic gangliaSMED30008828SMESG000009967.1 dd_Smed_v4_5075_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30008828SMESG000009967.1 dd_Smed_v4_5075_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30008828SMESG000009967.1 dd_Smed_v4_5075_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
reproductive organSMED30008828SMESG000009967.1 Contig39737newmark_estsPMID:28434803
Rouhana et al., 2017		whole organism adult hermaphrodite RNA-sequencing evidence
reproductive organSMED30008828SMESG000009967.1 Contig39737uc_Smed_v2PMID:28434803
Rouhana et al., 2017		whole organism adult hermaphrodite RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Slc15a-8 vs. Ensembl Xenopus
Match: slc9a3r1 (SLC9A3 regulator 1 [Source:Xenbase;Acc:XB-GENE-487362])

HSP 1 Score: 56.6102 bits (135), Expect = 7.685e-8
Identity = 58/199 (29.15%), Postives = 85/199 (42.71%), Query Frame = 2 
Query:  848 DLSKTIIVLFLLIPYSACDVQNKYGYVYQWLHMKWPNSTHYISDRISSIPKIINNLSTI------LF-AVFYIILTESNVTYLKAFFRNMKW------NIIVGILIMILATLISGVIETFRLEIFWNWNSQSLVPSPDAINQTSGTETYRAANLTAFVMVLPIVLNALSEVLVSVSCLDFLFRQSIKYLSISMYLGVIG 1405
             L K I V   LIPY     Q +  YV Q LH+K              IP I NN  T+      +F AV  +IL       +  F +           I VG+  ++ + L +G++E+ RLEI  N          D I Q  G  TY AANL  +  +   +L  +SE+  S++ L+F +  + K    SM   ++G
Sbjct:  322 SLVKIIPVFLALIPYWTVYFQMQTTYVLQSLHLK--------------IPPIFNNNHTLPAAWLTMFDAVLILILIPLKDKMVDPFLKKRGLLPSPLKRIAVGMFFVMCSVLAAGILESKRLEIVKN----------DKIQQQIGGVTYYAANLAVWWQLPQYILIGISEIFASIAGLEFAYSAAPK----SMQSAIMG 492
[Close]
BLAST of Slc15a-8 vs. UniProt/SwissProt
Match: sp|Q68F72|S15A4_XENLA (Solute carrier family 15 member 4 OS=Xenopus laevis OX=8355 GN=slc15a4 PE=2 SV=1)

HSP 1 Score: 56.225 bits (134), Expect = 6.494e-7
Identity = 54/189 (28.57%), Postives = 82/189 (43.39%), Query Frame = 2 
Query:  851 LSKTIIVLFLLIPYSACDVQNKYGYVYQWLHMKWPNSTHYISDRISSIPKIINNLSTI------LF-AVFYIILTESNVTYLKAFFRNMKW------NIIVGILIMILATLISGVIETFRLEIFWNWNSQSLVPSPDAINQTSGTETYRAANLTAFVMVLPIVLNALSEVLVSVSCLDFLFRQSIKYLS 1378
            L K I V   LIPY     Q +  YV Q LH++              IP+I NN  T+      +F AV  +IL       +  F +           I VG+  ++ + L +G++E+ RLEI             D I Q  G  TY AANLT +  +   +L  +SE+  S++ L+F +  + K + 
Sbjct:  322 LVKIIPVFLALIPYWTVYFQMQTTYVLQSLHLR--------------IPQIFNNNHTLPAAWLTMFDAVLILILIPLKDKLVDPFLKKRGLLPSPLKRIAVGMFFVMCSVLAAGILESERLEIV----------KRDKIQQQIGNVTYYAANLTVWWQLPQYILIGISEIFASIAGLEFAYSAAPKSMQ 486
[Close]
BLAST of Slc15a-8 vs. TrEMBL
Match: A0A0H3YJ38 (Slc15a-8 OS=Schmidtea mediterranea OX=79327 GN=slc15a-8 PE=2 SV=1)

HSP 1 Score: 219.164 bits (557), Expect = 6.506e-61
Identity = 164/498 (32.93%), Postives = 269/498 (54.02%), Query Frame = 2 
Query:  173 SSLYVIIIYFLMYMPYVYMQ-NISTFRIGEDIAAEFYILIIKI--FVVILSGILATFVIPSKILFAFSIAVLSISLLIFEIGEFNENLQKLKSIYRANL---LLNSVFFGIFRLICQILIYHQKSLNENLENSDVNSGNIKREICIWFVILNVTEVIVLAAMPLPSDNNPNLSIVCILSVTLGIILIITGKYFNFYKFDSEIGDIFQLIRNLKKPKGRFFS-VDL-QGKQFLIDLSKTIIVLFLLIPYSACDVQNKYGYVYQWLHMKWPN---STHYISDRISSIPKIINNLSTILFAVFYIILTESNVT-YLKAFFRNMKWNIIVGILIMILATLISGVIETFRLEIFWNWNSQSLVPSPDAINQTSGTETYRAANLTAFVMVLPIVLNALSEVLVSVSCLDFLFRQ---SIKYLSISMYLGVIGHGAFGELFSLIIYTTSKMFDSKHLNRRVPKSGTGGCCEKQSRLDCFYYVLGLLAFLCLLIDAFIMRKLWNRF 1621
            S ++++++YF +Y  ++++Q NI    +         +L++ I    V+L G+LATFV P   L   S++ L I +  F    F  N + ++   R NL   ++  +F+G FRL+   +I  Q+            S  IKR+I  W  ++N + ++V   +P P  + PNL +  +    +GIIL+  GK+   Y  DS I ++FQL++     +    S  D+   ++ LI +SK+II  FLLIPY  CD Q ++ Y YQ  HMK PN   S   ++ + +  P  +N L+ IL     I+L E N + +++  F ++K  II G ++MIL+T I G++E FRL I+W+++ ++ +PS  + NQT G  TY+AA+LT F MV  IVL+ +SEV+++ +C++F+++Q   SIKYL I+++L   G G F +LF   IYT         LN           C     LD  Y+ L  +AF   +I   ++ +  +RF
Sbjct:    8 SFVFLLVVYFFIYTAFLHVQVNIQAGSLVSSFPKYTNVLLVAIESSSVLLIGLLATFVFPVYFLLIISLSSLMIGISFFTAVAFLNNTKDIQ--LRLNLGGIIMFGIFYGTFRLLLLCMILDQE-----------QSHFIKRKIIGWLGVINFSFILVYM-IPSPIQH-PNLMLFPVSFSIIGIILLFFGKFRKIYAVDSNIVNVFQLMKRFNWSEELLISEADINDSERNLISISKSIIFFFLLIPYGICDSQTRFAYQYQSNHMKIPNWNGSLSSLTRKSNFWPITLNCLTVILAYFVLILLKEMNKSQFIQMLFSSIKLQIITGNILMILSTTIGGILELFRLNIYWSYDPKARIPSIYSFNQTIGNITYKAADLTVFAMVPQIVLDGISEVIITTTCIEFMYKQSKKSIKYLGIALFLAADGSGGFSDLF-FTIYTFYHESLENDLNN----------CH----LDYIYFGLAGVAFFSWIISIILINRFPHRF 475
[Close]
BLAST of Slc15a-8 vs. TrEMBL
Match: A0A0H3YK61 (Slc15a-7 (Fragment) OS=Schmidtea mediterranea OX=79327 GN=slc15a-7 PE=2 SV=1)

HSP 1 Score: 116.701 bits (291), Expect = 4.107e-24
Identity = 108/399 (27.07%), Postives = 194/399 (48.62%), Query Frame = 2 
Query:  305 VILSGILATFVIPSKILFAFSIA--VLSISLLIFEIGEFNENLQKLKSIYRANLLLNSVFFGIFRLICQILIYHQKSLNENLENSDVNSGNIKREICIWFVILNVTEVIVLAAMPLPSDNNP--NLSIVCILSVTLGIILIITGKYFNFYKFDSEIGDIFQLIRNLKKPKGRFFSVDLQG-----------KQFLIDLSKTIIVLFLLIPYSACDVQNKYGYVYQWLHMKWPN--STHYISDRISSIPKIINNLST--ILFAVFYIILTESNVTYLKAFFRNMKWNIIVGILIMILATLISGVIETFRLEIFWNWNSQSLVPSPDAINQTSGTETYRAANLTAFVMVLPIVLNALSEVLVSVSCLDFLF---RQSIKYLSISMYLGVIGHGAFGELFSL 1435
            +IL G+LATF+I ++ LF  SI   V+ + +L+F+   F +      ++Y    +L  + FG+F+ I  + +  Q            +   IK  +  +    ++  +IV    P         NL+   +     G IL++ G +   ++ D+E+ +++ +I+  ++   R F+ +L             ++ +I +SK++IV FLLIPY  CD Q  Y Y +Q   +   N    H+ S+   +       ++T  ILFAV +      N     A + N+K  II+G  +MI++TLI G +ET+RL + W  N+ +L  +P+  N      TY   +++ F MV   +L + SEVL+  +C++++     +S KYLSI +    +  G   +L S+
Sbjct:   61 LILGGMLATFLIRAQYLFYLSIGCFVIGVPILLFK-TPFTD-----PTLYWVTHVLIGLSFGLFKFIYLVALIDQN-----------DRRYIKFIVAFFLFTESICYLIVYTFTPNTDTVEKIWNLNYARLALAGFGAILVVIGCFLKLFEKDTEVIELYGIIQFFRQ---RRFAGNLDHSILNNTETVDFRKVIISISKSVIVFFLLIPYGICDSQEFYAYEFQSNSLNQSNLLFNHFKSNFWCNTISAFTVMATLLILFAVRF-----CNENKFDAIYSNIKTKIILGNSLMIISTLICGALETYRLSMLWTDNNSTL--TPNYKNVIIDNTTYHVVDISVFWMVPQNILLSFSEVLIVPTCIEYVIDKSEKSTKYLSIVLVFSAVNIGGISDLISM 432
[Close]
BLAST of Slc15a-8 vs. TrEMBL
Match: K1RF99 (Solute carrier family 15 member 4 OS=Crassostrea gigas OX=29159 GN=CGI_10015896 PE=4 SV=1)

HSP 1 Score: 68.9366 bits (167), Expect = 2.072e-8
Identity = 70/270 (25.93%), Postives = 120/270 (44.44%), Query Frame = 2 
Query:  848 DLSKTIIVLFLLIPYSACDVQNKYGYVYQWLHMKWP-------------NSTHYISDRISSIPKIINNLSTILFAVFYIILTE--SNVTYLKAFFRNMKWNII----VGILIMILATLISGVIETFRLEIFWNWNSQSLVPSPDAINQTSGTETYRAANLTAFVMVLPIVLNALSEVLVSVSCLDFLFR---QSIKYLSISMYLGVIGHGAFGELFSLIIYTTSKMF--DSKHLNRRVPKSGTGGCCEKQSRLDCFYYVLGLLAFLCLLI 1585
             L K + V   L+PY     Q +  +  Q LHMK               NS+ Y S   +    ++    ++   VF IIL      V Y     R+M   I+    VG++   +A L++G++E FRL   W + ++        INQT G   YRAA+++ F  +    L  +SEV  SV+ L+F ++   +S+K + +  +    G G+     ++  +  +  F  D  ++N R+    T G   K   LD +++ L +L F  + +
Sbjct:  332 QLLKILCVFLTLLPYWMVYFQMQTTFELQGLHMKLDISNVEKYKICHDMNSSSY-SPESTKKSTLVAAWFSLFDVVFLIILLPLFDRVIYPYLKKRDMHVGIVCRISVGMMFATIAVLVAGIVELFRLRAVWKFPNEECCSY--TINQTIGHTVYRAADMSVFWQIPQYALIGISEVFTSVAALEFAYQMAPKSMKGIIMGFFYLFTGIGSLLGTGTMFAFKDTWFFQEDFGNINCRM-GCNTTGTFTKACHLDYYFFFLAVLEFTGMFV 597
[Close]
BLAST of Slc15a-8 vs. TrEMBL
Match: A0A3M7SSZ3 (Solute carrier family 15 member 4 OS=Brachionus plicatilis OX=10195 GN=BpHYR1_023220 PE=3 SV=1)

HSP 1 Score: 63.1586 bits (152), Expect = 1.381e-6
Identity = 70/258 (27.13%), Postives = 118/258 (45.74%), Query Frame = 2 
Query:  749 DSEIGDIFQLIRNLKKPK----GRFFSVDLQGKQFLIDLSKTIIVLF-LLIPYSACDVQNKYGYVYQWLHMKWPNSTHYISDRISSIPKIINNLSTILFAVFYIILTESNV-TYLKAFFRNMK---WNIIVGILIMILATLISGVIETFRLEIFWNWNSQSLVPSPDAINQTSGTETYRAANLTAFVMVLPIVLNALSEVLVSVSCLDFLFRQSIKYLSISMYLGVI----GHGAFGE-----LFSLIIYTTSKMFDS 1468
            + + G  ++ I  L   K    GRF   D+   + L    K I++LF LLIPY     Q +  Y+ Q LHMK  + +  I      IP    +++  +  +F I L +S V  +++  F+N+      ++ G+ +  L+ + +G++E+ R  +       +  P  + + Q     +Y AANL     +    L  L EV  SV+CL + + ++ K +  SM +G+     G G+        LF  IIYT SK  D 
Sbjct:  342 EDDSGTSYKTISFLDNAKIRFGGRFADSDVDDVKSL----KRILLLFALLIPYWILYFQIETSYIIQGLHMKLFSRSETIGIPAFMIPAAWLSIADNVTVLFMIPLMDSLVYPFMRRRFKNLSIESTRLVFGMSLSALSVISAGILESVRHNLI------TEDPQANTVVQIIDNTSYVAANLNILWQIPQYTLTGLGEVFCSVTCLYYAYSEAPKSMQ-SMIMGLFYFFSGAGSLAGSAILVLFKKIIYTNSKNIDD 588
[Close]
BLAST of Slc15a-8 vs. TrEMBL
Match: E9G4U4 (Uncharacterized protein (Fragment) OS=Daphnia pulex OX=6669 GN=DAPPUDRAFT_30917 PE=3 SV=1)

HSP 1 Score: 60.8474 bits (146), Expect = 6.512e-6
Identity = 67/265 (25.28%), Postives = 118/265 (44.53%), Query Frame = 2 
Query:  848 DLSKTIIVLFLLIPYSACDVQNKYGYVYQWLHMKWP-NSTHYISDRISSIPKIINNLSTILFA------VFYIILTESNVTYLKAFFRNMKWNIIVGILIMILATLISGVIETFRLEIFWNWNSQSLVPSPDAINQTSGTETYRAANLTAFVMVLPIVLNALSEVLVSVSCLDFLFR---QSIKYLSISMYLGVIGHGAFGELFSLIIYTTSKM-----FDSKHLNRRVPKSGTGGCCEKQSRLDCFYYVLGLLAFLCLLIDAFI 1597
              SKT+I +F+L+PY     Q    +  Q LHM    N T+    +I +    + + + +LF       V Y IL ++N+T +          I+VG+LI +LA +++ V+E FRLEI   WN        ++INQ      Y A+ ++    +    L   +EV   V+ L++ +    +S + + + +Y  + G G+F  L  L++  T  +         H N              Q  LD F+Y+L ++    ++I   +
Sbjct:  295 SFSKTMIFIFVLLPYWLVYFQMSTSFQAQGLHMNLHLNGTYNPDFQIPAAWLTLCDEAFVLFLIPLLNFVIYPILDKNNITTVPLC------RIVVGMLISLLAVIVAAVVEHFRLEI---WNQG------NSINQIISNTNYNASAMSILYQIPQYCLIGTAEVFAGVAGLEYAYTTAPRSFQGIVLGLYSAIEGLGSF--LGVLLVQITRSLQLGWIRSEVHFN--------------QGHLDYFFYLLAIIQSAVVIISGLV 528
[Close]
BLAST of Slc15a-8 vs. Ensembl Cavefish
Match: slc15a4 (solute carrier family 15 member 4 [Source:NCBI gene;Acc:103028949])

HSP 1 Score: 54.299 bits (129), Expect = 2.653e-7
Identity = 49/183 (26.78%), Postives = 81/183 (44.26%), Query Frame = 2 
Query:  848 DLSKTIIVLFLLIPYSACDVQNKYGYVYQWLHMKWPNSTHYISDRISSIPKIINNLSTILFAVFYIILTESNVTYLKAFFRNMKW------NIIVGILIMILATLISGVIETFRLEIFWNWNSQSLVPSPDA-INQTSGTETYRAANLTAFVMVLPIVLNALSEVLVSVSCLDFLFRQSIKYL 1375
             L K + V   LIPY     Q +  Y  Q LH++ P S   ++D  +   K      T+  AV  ++L       +    R           I VG+  ++ + + +G++ET RLEI         V SP   I+Q  G  TY AA+L  +  +   VL  +SE+  S++ L+F +  + + +
Sbjct:  315 SLMKILPVFLALIPYWTVYFQMQTTYYLQSLHLRIPGSEANVTDSQTMRFKFPAAWLTMFDAVLILMLIPLKDKLVDPILRRRGLLPSSLKRIAVGMFFVMCSAVAAGILETKRLEI---------VNSPHGVISQVLGGVTYYAADLPIWWQIPQYVLIGISEIFASIAGLEFAYSAAPRSM 488
[Close]
BLAST of Slc15a-8 vs. Ensembl Cavefish
Match: slc15a4 (solute carrier family 15 member 4 [Source:NCBI gene;Acc:103028949])

HSP 1 Score: 53.9138 bits (128), Expect = 3.141e-7
Identity = 49/183 (26.78%), Postives = 81/183 (44.26%), Query Frame = 2 
Query:  848 DLSKTIIVLFLLIPYSACDVQNKYGYVYQWLHMKWPNSTHYISDRISSIPKIINNLSTILFAVFYIILTESNVTYLKAFFRNMKW------NIIVGILIMILATLISGVIETFRLEIFWNWNSQSLVPSPDA-INQTSGTETYRAANLTAFVMVLPIVLNALSEVLVSVSCLDFLFRQSIKYL 1375
             L K + V   LIPY     Q +  Y  Q LH++ P S   ++D  +   K      T+  AV  ++L       +    R           I VG+  ++ + + +G++ET RLEI         V SP   I+Q  G  TY AA+L  +  +   VL  +SE+  S++ L+F +  + + +
Sbjct:  315 SLMKILPVFLALIPYWTVYFQMQTTYYLQSLHLRIPGSEANVTDSQTMRFKFPAAWLTMFDAVLILMLIPLKDKLVDPILRRRGLLPSSLKRIAVGMFFVMCSAVAAGILETKRLEI---------VNSPHGVISQVLGGVTYYAADLPIWWQIPQYVLIGISEIFASIAGLEFAYSAAPRSM 488
[Close]
BLAST of Slc15a-8 vs. Ensembl Medaka
Match: slc15a4 (solute carrier family 15 member 4 [Source:NCBI gene;Acc:101165813])

HSP 1 Score: 59.6918 bits (143), Expect = 4.613e-9
Identity = 52/188 (27.66%), Postives = 85/188 (45.21%), Query Frame = 2 
Query:  851 LSKTIIVLFLLIPYSACDVQNKYGYVYQWLHMKWPNSTHYISDRISSIPKIINNLSTILFAVFYIILTESNVTYL---KAFFRNMKWNIIVGILIMILATLISGVIETFRLEIFWNWNSQSLVPSPDAINQTSGTETYRAANLTAFVMVLPIVLNALSEVLVSVSCLDFLFRQSIKYLSISMYLGVIG 1405
            L KT+ V F LIPY     Q +  YV Q LH++ P ++  I+      P     +   +  +  I L +  V  +   +    +    I VG+  ++ + + +G++ET RLEI         V S   INQ  G   Y  A+L  +  V   VL  +SE+  S++ L+F +  + K    SM   ++G
Sbjct:  307 LLKTLPVFFALIPYWTVYFQMQTTYVLQGLHLRIPGTSSNITTESHQFPAAWLTMFDAVLILMLIPLKDKVVDPVLKRRGLLPSSLKRIAVGMFFVMCSAVAAGILETKRLEI---------VKSNGTINQVLGNVIYYVADLPIWWQVPQYVLIGISEIFASIAGLEFAYSAAPK----SMQSAIMG 481
[Close]
BLAST of Slc15a-8 vs. Ensembl Medaka
Match: slc15a4 (solute carrier family 15 member 4 [Source:NCBI gene;Acc:101165813])

HSP 1 Score: 55.0694 bits (131), Expect = 1.339e-7
Identity = 53/192 (27.60%), Postives = 86/192 (44.79%), Query Frame = 2 
Query:  851 LSKTIIVLFLLIPYSACDVQNKYGYVYQWLHMKWPNSTHYISDRISSIP-KIINNLSTILFAVFYIILTE------SNVTYLKAFFRNMKWNIIVGILIMILATLISGVIETFRLEIFWNWNSQSLVPSPDAINQTSGTETYRAANLTAFVMVLPIVLNALSEVLVSVSCLDFLFRQSIKYLSISMYLGVIG 1405
            L KT+ V F LIPY     Q +  YV Q LH++ P ++  I+     +  +      T+  AV  ++L          V   +    +    I VG+  ++ + + +G++ET RLEI         V S   INQ  G   Y  A+L  +  V   VL  +SE+  S++ L+F +  + K    SM   ++G
Sbjct:  315 LLKTLPVFFALIPYWTVYFQMQTTYVLQGLHLRIPGTSSNITTESHQMTFQFPAAWLTMFDAVLILMLIPLKDKVVDPVLKRRGLLPSSLKRIAVGMFFVMCSAVAAGILETKRLEI---------VKSNGTINQVLGNVIYYVADLPIWWQVPQYVLIGISEIFASIAGLEFAYSAAPK----SMQSAIMG 493
[Close]
BLAST of Slc15a-8 vs. Ensembl Medaka
Match: slc15a4 (solute carrier family 15 member 4 [Source:NCBI gene;Acc:101165813])

HSP 1 Score: 55.0694 bits (131), Expect = 1.339e-7
Identity = 53/192 (27.60%), Postives = 86/192 (44.79%), Query Frame = 2 
Query:  851 LSKTIIVLFLLIPYSACDVQNKYGYVYQWLHMKWPNSTHYISDRISSIP-KIINNLSTILFAVFYIILTE------SNVTYLKAFFRNMKWNIIVGILIMILATLISGVIETFRLEIFWNWNSQSLVPSPDAINQTSGTETYRAANLTAFVMVLPIVLNALSEVLVSVSCLDFLFRQSIKYLSISMYLGVIG 1405
            L KT+ V F LIPY     Q +  YV Q LH++ P ++  I+     +  +      T+  AV  ++L          V   +    +    I VG+  ++ + + +G++ET RLEI         V S   INQ  G   Y  A+L  +  V   VL  +SE+  S++ L+F +  + K    SM   ++G
Sbjct:  315 LLKTLPVFFALIPYWTVYFQMQTTYVLQGLHLRIPGTSSNITTESHQMTFQFPAAWLTMFDAVLILMLIPLKDKVVDPVLKRRGLLPSSLKRIAVGMFFVMCSAVAAGILETKRLEI---------VKSNGTINQVLGNVIYYVADLPIWWQVPQYVLIGISEIFASIAGLEFAYSAAPK----SMQSAIMG 493
[Close]
BLAST of Slc15a-8 vs. Planmine SMEST
Match: SMESG000009967.1 (SMESG000009967.1)

HSP 1 Score: 978.393 bits (2528), Expect = 0.000e+0
Identity = 484/504 (96.03%), Postives = 496/504 (98.41%), Query Frame = 2 
Query:  158 MCQMKSSLYVIIIYFLMYMPYVYMQNISTFRIGEDIAAEFYILIIKIFVVILSGILATFVIPSKILFAFSIAVLSISLLIFEIGEFNENLQKLKSIYRANLLLNSVFFGIFRLICQILIYHQKSLNENLENSDVNSGNIKREICIWFVILNVTEVIVLAAMPLPSDNNPNLSIVCILSVTLGIILIITGKYFNFYKFDSEIGDIFQLIRNLKKPKGRFFSVDLQGKQFLIDLSKTIIVLFLLIPYSACDVQNKYGYVYQWLHMKWPNSTHYISDRISSIPKIINNLSTILFAVFYIILTESNVTYLKAFFRNMKWNIIVGILIMILATLISGVIETFRLEIFWNWNSQSLVPSPDAINQTSGTETYRAANLTAFVMVLPIVLNALSEVLVSVSCLDFLFRQSIKYLSISMYLGVIGHGAFGELFSLIIYTTSKMFDSKHLNRRVPKSGTGGCCEKQSRLDCFYYVLGLLAFLCLLIDAFIMRKLWNRFKNNNEVGNGENLPDVN 1669
            MCQMKSSLYVIIIYFLMYMPYVYMQNISTFRIG+DIAAEFYILIIKIFVVILSGILATFVIPSKILFAFSIAVLSISLLIFEIGEFNENLQKLKSI  ANL+LNS+FFGIFRLICQILIYHQK+LNENLENSDVNSGN+KREICIW VILNVTEVIVLAAMPLP+DNNPNLSIVCILSVTLGIILIITGKY+NFYKFDSEIGDIFQLIRNLKKPKGRFFSVDLQGKQFLIDLSKTIIVLFLLIPYSACDVQNKYGYVYQWLHMKWPNST YISDRISSIPKIIN LSTILFAVFYIILTE+NVTYLKAFFRNMKWNIIVGILIMILATLISGVIETFRLEIFWNWNS+SLVPSPDAINQTSGTETYRAANLTAFVMVLPIVLNALSEVLVSVSCLDFLFRQSIKYLSISMYLGVIGHGAFGELFSLIIY TS MFDSKHLN+RVPKS TGGCC++QSRLDCFYYVLGLLAFLCLLIDAFIMRKLWNRFKNNNEVGNGENLPDVN
Sbjct:    1 MCQMKSSLYVIIIYFLMYMPYVYMQNISTFRIGKDIAAEFYILIIKIFVVILSGILATFVIPSKILFAFSIAVLSISLLIFEIGEFNENLQKLKSISMANLVLNSIFFGIFRLICQILIYHQKTLNENLENSDVNSGNVKREICIWLVILNVTEVIVLAAMPLPTDNNPNLSIVCILSVTLGIILIITGKYYNFYKFDSEIGDIFQLIRNLKKPKGRFFSVDLQGKQFLIDLSKTIIVLFLLIPYSACDVQNKYGYVYQWLHMKWPNSTLYISDRISSIPKIINGLSTILFAVFYIILTENNVTYLKAFFRNMKWNIIVGILIMILATLISGVIETFRLEIFWNWNSKSLVPSPDAINQTSGTETYRAANLTAFVMVLPIVLNALSEVLVSVSCLDFLFRQSIKYLSISMYLGVIGHGAFGELFSLIIYNTSYMFDSKHLNKRVPKSATGGCCKEQSRLDCFYYVLGLLAFLCLLIDAFIMRKLWNRFKNNNEVGNGENLPDVN 504
[Close]
BLAST of Slc15a-8 vs. Planmine SMEST
Match: SMESG000009956.1 (SMESG000009956.1)

HSP 1 Score: 212.231 bits (539), Expect = 6.377e-62
Identity = 159/496 (32.06%), Postives = 266/496 (53.63%), Query Frame = 2 
Query:  173 SSLYVIIIYFLMYMPYVYMQ-NISTFRIGEDIAAEFYILIIKI--FVVILSGILATFVIPSKILFAFSIAVLSISLLIFEIGEFNENLQKLK-SIYRANLLLNSVFFGIFRLICQILIYHQKSLNENLENSDVNSGNIKREICIWFVILNVTEVIVLAAMPLPSDNNPNLSIVCILSVTLGIILIITGKYFNFYKFDSEIGDIFQLIRNLKKPKGRFFS-VDL-QGKQFLIDLSKTIIVLFLLIPYSACDVQNKYGYVYQWLHMKWPN---STHYISDRISSIPKIINNLSTILFAVFYIILTESNVT-YLKAFFRNMKWNIIVGILIMILATLISGVIETFRLEIFWNWNSQSLVPSPDAINQTSGTETYRAANLTAFVMVLPIVLNALSEVLVSVSCLDFLFRQ---SIKYLSISMYLGVIGHGAFGELFSLIIYTTSKMFDSKHLNRRVPKSGTGGCCEKQSRLDCFYYVLGLLAFLCLLIDAFIMRKLWNRF 1621
            S ++++++Y  +Y  ++Y+Q NI    +         +L++ I    V+L G+LATFV P   L   S++ L I +  F    F  N + ++ ++    +++  +F+G FRL+   +I  Q+            S  IKR+I  W  ++N + ++V   +P P  + PNL +  +    +GIIL++ GK+   Y  DS I ++FQL++     +       D+   ++ LI +SK+II  FLLIPY  CD Q ++ Y YQ  HMK PN   S   ++ + +  P  +N L+ IL    +I+L E N + +++  F ++K  II G ++MIL+T I G++E FRL I+W  + ++ + S  + NQT G  TY+AA+LT F MV  IVL+ +SEV+++ +C++F+++Q   SIKYL I+++L   G G F +LF   IYT         LN           C     LD  Y+ L  +AF   +I   ++ +  +RF
Sbjct:    8 SFVFLLVVYLFIYTAFLYVQVNIQADSMVSSFPKYTNVLLVAIESSSVLLIGLLATFVFPVFFLLIISLSSLMIGISFFTAVAFLNNKEDIQLTLNLCGIIMFGIFYGTFRLLLLCMILDQE-----------QSHFIKRKIIGWLGVINFSFILVYM-IPSPIQH-PNLMLFPVSFSIIGIILLVFGKFRKIYAVDSNIVNVFQLMKRFNWSEELLIDEADINDSERNLISISKSIIFFFLLIPYGICDSQTRFAYQYQSNHMKIPNWNGSLSSLTRKSNFWPITLNCLTVILAYFVFILLKEMNKSQFIQMLFSSIKLQIITGNILMILSTTIGGILELFRLNIYWRNDPKAGIQSIYSFNQTIGNITYKAADLTVFAMVPQIVLDGISEVIITTTCIEFMYKQSKKSIKYLGIALFLAADGSGGFSDLF-FTIYTFYHESLENDLNN----------CH----LDYIYFGLAGVAFFSWIISIILINRFPHRF 475
[Close]
BLAST of Slc15a-8 vs. Planmine SMEST
Match: SMESG000009956.1 (SMESG000009956.1)

HSP 1 Score: 207.223 bits (526), Expect = 2.165e-60
Identity = 149/449 (33.18%), Postives = 242/449 (53.90%), Query Frame = 2 
Query:  305 VILSGILATFVIPSKILFAFSIAVLSISLLIFEIGEFNENLQKLK-SIYRANLLLNSVFFGIFRLICQILIYHQKSLNENLENSDVNSGNIKREICIWFVILNVTEVIVLAAMPLPSDNNPNLSIVCILSVTLGIILIITGKYFNFYKFDSEIGDIFQLIRNLKKPKGRFFS-VDL-QGKQFLIDLSKTIIVLFLLIPYSACDVQNKYGYVYQWLHMKWPN---STHYISDRISSIPKIINNLSTILFAVFYIILTESNVT-YLKAFFRNMKWNIIVGILIMILATLISGVIETFRLEIFWNWNSQSLVPSPDAINQTSGTETYRAANLTAFVMVLPIVLNALSEVLVSVSCLDFLFRQ---SIKYLSISMYLGVIGHGAFGELFSLIIYTTSKMFDSKHLNRRVPKSGTGGCCEKQSRLDCFYYVLGLLAFLCLLIDAFIMRKLWNRF 1621
            V+L G+LATFV P   L   S++ L I +  F    F  N + ++ ++    +++  +F+G FRL+   +I  Q+            S  IKR+I  W  ++N + ++V   +P P  + PNL +  +    +GIIL++ GK+   Y  DS I ++FQL++     +       D+   ++ LI +SK+II  FLLIPY  CD Q ++ Y YQ  HMK PN   S   ++ + +  P  +N L+ IL    +I+L E N + +++  F ++K  II G ++MIL+T I G++E FRL I+W  + ++ + S  + NQT G  TY+AA+LT F MV  IVL+ +SEV+++ +C++F+++Q   SIKYL I+++L   G G F +LF   IYT         LN                 LD  Y+ L  +AF   +I   ++ +  +RF
Sbjct:   21 VLLIGLLATFVFPVFFLLIISLSSLMIGISFFTAVAFLNNKEDIQLTLNLCGIIMFGIFYGTFRLLLLCMILDQE-----------QSHFIKRKIIGWLGVINFSFILVYM-IPSPIQH-PNLMLFPVSFSIIGIILLVFGKFRKIYAVDSNIVNVFQLMKRFNWSEELLIDEADINDSERNLISISKSIIFFFLLIPYGICDSQTRFAYQYQSNHMKIPNWNGSLSSLTRKSNFWPITLNCLTVILAYFVFILLKEMNKSQFIQMLFSSIKLQIITGNILMILSTTIGGILELFRLNIYWRNDPKAGIQSIYSFNQTIGNITYKAADLTVFAMVPQIVLDGISEVIITTTCIEFMYKQSKKSIKYLGIALFLAADGSGGFSDLF-FTIYTFYHESLENDLN--------------NCHLDYIYFGLAGVAFFSWIISIILINRFPHRF 441
[Close]
BLAST of Slc15a-8 vs. Planmine SMEST
Match: SMESG000023324.1 (SMESG000023324.1)

HSP 1 Score: 122.094 bits (305), Expect = 1.800e-29
Identity = 119/473 (25.16%), Postives = 219/473 (46.30%), Query Frame = 2 
Query:  305 VILSGILATFVIPSKILFAFSIAVLSISLLIFE-IGEFNENLQKLKSIYRANLLLNSVFFGIFRLICQILIYHQKSLNENLENSDVNSGNIKREICIWFVILNVTEVIVLAAMPLPSDNNPNLSIVCILSVTLGIILIITGKYFNFYKFDSEIGDIFQLIRNLKKPKGRFFSV--------DLQGKQFLIDLSKTIIVLFLLIPYSACDVQNKYGYVYQWLHMKWPNSTHYISDRISSIPKIINNLSTILFAVFYIILTESNVTYLKAF---FRNMKWNIIVGILIMILATLISGVIETFRLEIFWNWNSQSLVPSPDAINQTSGTETYRAANLTAFVMVLPIVLNALSEVLVSVSCLDFLF---RQSIKYLSISMYLGVIGHGAFGELFSLIIY---TTSKMFDSKHLNRRVPKSGTGGCCEKQSRLDCFYYVLGLLAFLCLLIDAFIMRKLWNRFKNNNEVGNGENLPDVN 1669
            ++L GILATF+I +  LF  S     + + IFE    F +        Y    LL  +  G+F+ +  + +  Q     + +    N        C  ++I     V    +     +NN    +  +L+V LG IL++ G +   ++ +SE+ +++ +I+ +++ K  + S          +  K+ +I +SK++IV  LLIPY  CD Q  Y Y YQ   ++ P+   Y +    S     N +++++  +  +IL  +     KAF   +  MK  II+G + MI++TLI G +ETFRL   W  N+ S+  + +  N T   +TY   N++   M+   +L + SE+LV  +C++++     +S KY ++++ + V+  G   +  ++I+     T   FDS                +   RLD   Y++  ++ + L+I   +M     RFK    +     + +VN
Sbjct:   56 LLLGGILATFLIRAHYLFYLSFGCFLLGIAIFEWKAPFTDG-----GFYWTVELLIGISLGLFKFLYIVALIDQ----NDRKYIKFNVAFFLFSDCFCYLI-----VYTFTSNKASDENNTKTYVRRVLAV-LGTILVVIGIFVKRFERNSEVIELYGIIKFIRQRKSFYESEYEMINNVGAVHYKKVIISISKSVIVFLLLIPYGICDSQQLYAYAYQSNSLRPPHGNRYFTSDFWS-----NTITSMIVIMTLLILLSARFLNEKAFDKLYSKMKAKIILGNIFMIISTLICGALETFRLSTRWTANNSSV--TSNYKNMTIDKKTY--INMSVLCMIPQSILLSFSEILVIPTCIEYVILESEKSTKYFAVALIVSVVNIGGISDFLTVIMEFKNITPSDFDSNK--------------KATIRLDYLMYIISSVSVISLVISILLMV----RFKKYFTLDEFNKMEEVN 486
[Close]
BLAST of Slc15a-8 vs. Planmine SMEST
Match: SMESG000023325.1 (SMESG000023325.1)

HSP 1 Score: 118.242 bits (295), Expect = 2.787e-28
Identity = 109/401 (27.18%), Postives = 195/401 (48.63%), Query Frame = 2 
Query:  305 VILSGILATFVIPSKILFAFSIA--VLSISLLIFEIGEFNENLQKLKSIYRANLLLNSVFFGIFRLICQILIYHQKSLNENLENSDVNSGNIKREICIWFVILNVTEVIVLAAMPLPSDNNP--NLSIVCILSVTLGIILIITGKYFNFYKFDSEIGDIFQLIRNLKKPKGRFFSVDLQG-----------KQFLIDLSKTIIVLFLLIPYSACDVQNKYGYVYQWLHMKWPN------STHYISDRISSIPKIINNLSTILFAVFYIILTESNVTYLKAFFRNMKWNIIVGILIMILATLISGVIETFRLEIFWNWNSQSLVPSPDAINQTSGTETYRAANLTAFVMVLPIVLNALSEVLVSVSCLDFLF---RQSIKYLSISMYLGVIGHGAFGELFSL 1435
            +IL G+LATF+I ++ LF  SI   V+ + +L+F+   F +      ++Y    +L  + FG+F+ I  + +  Q            +   IK  +  +    ++  +IV    P         NL+   +     G IL++ G +   ++ D+E+ +I+ +I+  ++   R F+ +L             ++ +I +SK++IV FLLIPY  CD Q  Y Y +Q   +   N       +++  + IS+   +   L  ILFAV +      N     A + N+K  II+G  +MI++TLI G +ET+RL + W  N+ +L  +P+  N      TY   +++ F MV   +L + SEVL+  +C++++     +S KYLSI +    +  G   +L S+
Sbjct:   18 LILGGMLATFLIRAQYLFYLSIGCFVIGVPILLFK-TPFTD-----PTLYWVTHVLIGLSFGLFKFIYLVALIDQN-----------DRRYIKFIVAFFLFTESICYLIVYTFTPNTDTVEKIWNLNYARLALAGFGAILVVIGCFLKLFEKDTEVIEIYGIIQFFRQ---RRFAANLDHSILNNTETVDFRKVIISISKSVIVFFLLIPYGICDSQEFYAYEFQSNSLNQSNLLFNHFKSNFWCNTISAFTVMAALL--ILFAVRF-----CNENKFDAIYSNIKTKIILGNSLMIISTLICGALETYRLSMLWTDNNSTL--TPNYKNVIIDNTTYHVVDISVFWMVPQNILLSFSEVLIVPTCIEYVIDKSEKSTKYLSIVLVFSAVNIGGISDLISM 389
The following BLAST results are available for this feature:
BLAST of Slc15a-8 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Slc15a-8 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Slc15a-8 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Slc15a-8 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Slc15a-8 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 1
Match NameE-valueIdentityDescription
slc9a3r17.685e-829.15SLC9A3 regulator 1 [Source:Xenbase;Acc:XB-GENE-487... [more]
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BLAST of Slc15a-8 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Slc15a-8 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 1
Match NameE-valueIdentityDescription
sp|Q68F72|S15A4_XENLA6.494e-728.57Solute carrier family 15 member 4 OS=Xenopus laevi... [more]
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BLAST of Slc15a-8 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A0H3YJ386.506e-6132.93Slc15a-8 OS=Schmidtea mediterranea OX=79327 GN=slc... [more]
A0A0H3YK614.107e-2427.07Slc15a-7 (Fragment) OS=Schmidtea mediterranea OX=7... [more]
K1RF992.072e-825.93Solute carrier family 15 member 4 OS=Crassostrea g... [more]
A0A3M7SSZ31.381e-627.13Solute carrier family 15 member 4 OS=Brachionus pl... [more]
E9G4U46.512e-625.28Uncharacterized protein (Fragment) OS=Daphnia pule... [more]
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BLAST of Slc15a-8 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 2
Match NameE-valueIdentityDescription
slc15a42.653e-726.78solute carrier family 15 member 4 [Source:NCBI gen... [more]
slc15a43.141e-726.78solute carrier family 15 member 4 [Source:NCBI gen... [more]
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BLAST of Slc15a-8 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Slc15a-8 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Slc15a-8 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Slc15a-8 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 3
Match NameE-valueIdentityDescription
slc15a44.613e-927.66solute carrier family 15 member 4 [Source:NCBI gen... [more]
slc15a41.339e-727.60solute carrier family 15 member 4 [Source:NCBI gen... [more]
slc15a41.339e-727.60solute carrier family 15 member 4 [Source:NCBI gen... [more]
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BLAST of Slc15a-8 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000009967.10.000e+096.03SMESG000009967.1[more]
SMESG000009956.16.377e-6232.06SMESG000009956.1[more]
SMESG000009956.12.165e-6033.18SMESG000009956.1[more]
SMESG000023324.11.800e-2925.16SMESG000023324.1[more]
SMESG000023325.12.787e-2827.18SMESG000023325.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30008828 ID=SMED30008828|Name=Slc15a-8|organism=Schmidtea mediterranea sexual|type=transcript|length=1713bp
TGATCAAATATCATTGATTGAAAACTTTGAATTATTTTATTAAAAATTAA
TATATTTTGATTTATTTAGTATTTGAGTTAAAGTCAGATTATATTTTTTA
ATTTAGTAATAGTATAAATTAAATTTATTAATTGATAATTTGTAACTGCA
ATCTAAAATGTGTCAAATGAAATCATCTTTGTATGTAATTATTATTTATT
TCCTGATGTATATGCCATATGTGTATATGCAAAATATTTCAACTTTCCGC
ATTGGTGAAGACATTGCAGCCGAGTTTTATATTTTAATTATTAAAATTTT
CGTGGTTATTCTCTCAGGAATTTTAGCAACATTCGTAATCCCATCGAAGA
TTTTGTTTGCATTTTCCATTGCTGTGCTTTCCATCAGTCTTCTGATCTTT
GAGATTGGAGAGTTCAATGAGAATTTGCAAAAACTCAAATCGATTTACAG
GGCAAATTTGTTGTTGAATTCGGTTTTTTTCGGCATTTTCAGGCTGATTT
GTCAGATTTTGATTTACCACCAAAAAAGCCTCAACGAAAATTTAGAAAAT
TCTGATGTTAATTCAGGCAATATAAAACGTGAAATTTGCATCTGGTTCGT
CATATTGAATGTCACCGAGGTTATTGTACTTGCTGCGATGCCCCTCCCCA
GCGATAATAACCCCAATCTTTCAATTGTTTGTATTTTATCTGTTACACTT
GGAATCATTTTGATTATTACCGGAAAGTATTTTAATTTTTACAAATTCGA
TTCTGAGATTGGTGATATTTTTCAATTAATTCGAAATTTGAAAAAACCGA
AAGGAAGATTTTTTAGTGTGGATTTGCAAGGAAAACAATTTTTAATTGAT
TTATCTAAAACAATAATAGTTTTATTTCTTTTGATTCCATATAGTGCTTG
TGATGTGCAGAATAAATATGGCTACGTTTATCAATGGCTTCATATGAAAT
GGCCGAACAGCACGCATTATATTTCGGACAGAATTTCATCAATTCCGAAA
ATAATTAATAATTTATCAACAATTTTGTTTGCGGTTTTCTACATAATTCT
CACTGAAAGTAATGTAACTTATTTAAAAGCGTTCTTTCGGAATATGAAAT
GGAACATAATTGTTGGAATTCTTATAATGATATTAGCAACGTTGATCAGT
GGTGTTATCGAAACTTTTCGGTTAGAGATATTCTGGAATTGGAATTCGCA
GTCTCTGGTGCCCTCTCCAGATGCAATAAATCAAACCTCAGGTACAGAGA
CCTACAGGGCTGCCAACCTCACCGCTTTTGTCATGGTTCTTCCTATTGTT
TTGAATGCATTGAGTGAGGTTCTCGTATCTGTTTCATGTCTTGACTTTTT
ATTCCGACAATCTATCAAATATTTATCTATTTCCATGTATCTTGGGGTTA
TTGGCCATGGAGCTTTCGGAGAACTTTTTTCACTGATTATTTACACTACA
TCAAAAATGTTTGACTCGAAACATCTCAATAGGAGAGTACCAAAGTCGGG
TACTGGTGGTTGTTGTGAAAAGCAAAGCCGTTTGGATTGTTTCTATTATG
TTCTTGGACTTTTGGCATTTTTATGTTTGCTAATTGATGCTTTTATTATG
AGGAAGTTATGGAATCGGTTTAAGAATAATAATGAGGTCGGCAATGGTGA
AAATTTGCCTGATGTTAATTAATAAAATGACAAATAATATTAAATAAAGC
CTTTTATTATTAT
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protein sequence of SMED30008828-orf-1

>SMED30008828-orf-1 ID=SMED30008828-orf-1|Name=SMED30008828-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=505bp
MCQMKSSLYVIIIYFLMYMPYVYMQNISTFRIGEDIAAEFYILIIKIFVV
ILSGILATFVIPSKILFAFSIAVLSISLLIFEIGEFNENLQKLKSIYRAN
LLLNSVFFGIFRLICQILIYHQKSLNENLENSDVNSGNIKREICIWFVIL
NVTEVIVLAAMPLPSDNNPNLSIVCILSVTLGIILIITGKYFNFYKFDSE
IGDIFQLIRNLKKPKGRFFSVDLQGKQFLIDLSKTIIVLFLLIPYSACDV
QNKYGYVYQWLHMKWPNSTHYISDRISSIPKIINNLSTILFAVFYIILTE
SNVTYLKAFFRNMKWNIIVGILIMILATLISGVIETFRLEIFWNWNSQSL
VPSPDAINQTSGTETYRAANLTAFVMVLPIVLNALSEVLVSVSCLDFLFR
QSIKYLSISMYLGVIGHGAFGELFSLIIYTTSKMFDSKHLNRRVPKSGTG
GCCEKQSRLDCFYYVLGLLAFLCLLIDAFIMRKLWNRFKNNNEVGNGENL
PDVN*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: molecular function
TermDefinition
GO:0022857transmembrane transporter activity
GO:0005215transporter activity
Vocabulary: biological process
TermDefinition
GO:0055085transmembrane transport
GO:0006810transport
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000070intestinal phagocyte
PLANA:0000101muscle cell
PLANA:0002089reproductive organ
PLANA:0003001lateral region of the whole animal
PLANA:0003116parenchymal cell
Vocabulary: cellular component
TermDefinition
GO:0016020membrane
GO:0016021integral component of membrane
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableGENE3DG3DSA:1.20.1250.20coord: 174..499
e-value: 3.1E-15
score: 57.6
NoneNo IPR availableCDDcd17348MFS_SLC15A3_4coord: 219..404
e-value: 1.60274E-8
score: 54.4104
NoneNo IPR availableTMHMMTMhelixcoord: 407..429
NoneNo IPR availableTMHMMTMhelixcoord: 315..337
NoneNo IPR availableTMHMMTMhelixcoord: 98..120
NoneNo IPR availableTMHMMTMhelixcoord: 7..24
NoneNo IPR availableTMHMMTMhelixcoord: 143..165
NoneNo IPR availableTMHMMTMhelixcoord: 170..189
NoneNo IPR availableTMHMMTMhelixcoord: 39..61
NoneNo IPR availableTMHMMTMhelixcoord: 373..395
NoneNo IPR availableTMHMMTMhelixcoord: 66..83
NoneNo IPR availableTMHMMTMhelixcoord: 228..247
NoneNo IPR availableTMHMMTMhelixcoord: 462..481
NoneNo IPR availableTMHMMTMhelixcoord: 276..298