ADAM 17-like protease

Query:  110 LSDYDILPNLNIR--------ISRSTFDNKKISFSTKFRKFKLILKPSVDLLSNDLKSVNIDRFGRETPVPIDGSQFYQGFVSGAEKSSVSAFLGNDKMLSINIILDDDIFQVEPLSRYVQN--NSSFIVYRYSDLKGNFTR--GPK-CFAKNISSFETNTTNSRQKRNVDAIISLP--YINKDSTKKLCTIKLIADYRFHREHGRGEMGRTQHYLIELIDKINILFKSTDFVDSKNNKNSGYGFIINQILVHVEPTIGPSG--HYNQEVA---KQTDAWTVEGLLDSFG-DIDHKDS--CLAHLFTFQSFSEGTLGLAYMASSKTLSYGGICSERDFRHQNSKLVSVNTAWSTYRDAVGKRVISMSAYLVTAHELGHNWGADHDPD-TTDCAPNAARGGKYVMYTYSVVGYEPNNRLFSPCSRRSIGATIATRGEYCFLSPMNAFCGNSRVDDNEECDVG---KNNSADACCTSDCHFKPGAVCSPNNHECCTNDCQFKPYGFVCAAKDPMNP-CVNHSICSGKEKECLGPLSI-DGPNCTEHGRCSSGKCRPYCE-QLNMEACICDKIEESCLICCRDPPSKINSNTIQECRPAQNGIQSRLTLNQGRPCALGVCE-EGVCKRRVNKLVERIWKIIDEFNTNLFAAFLLENXXXXXXXXXXXXXXPAAILVSCNDAKHRRRF 2068
            LSDYDIL   NI+        +  ST     ++FS   R FKL L  S +  S + K V +D    E+   +    F+ G V G   S V A + +D ++ I I  D   + +EPL R+V +  +   +VY+  D+K N +R   PK C    + + E        +   + ++       + D  K  C + ++AD+RF+R  GRGE   T +YLIELID+++ ++++T +    N    GYG  I QI +   P     G  HYN   +   ++ DAW V+ LL+ F  DI  + S  CLAHLFT+Q F  GTLGLAY+ S +  S+GG+C +  +     K + +N+  ++ ++  GK +++  A LVT HELGHN+GA+HDPD   +CAPN  +GGKYVMY  +V G   NN++FS CS++SI  TI ++ + CF    N  CGNSRVD+ EECD G    NN  D CC SDC  K G  CS  N  CC N CQF+     C  ++ +N  C   S C+G   EC  P +  D   C + G+C  GKC P+CE +  +E+C C++ + SC +CCRD   +        C P  +  Q  L L +G+PC +G C+  G C++RV  ++ER W  ID+ + N F  FL +N+VG+V++ +LI WIP +ILV C D K  +++
Sbjct:   39 LSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDG-KNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVI-IRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIK-NVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSW---DNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKN-YGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNN--DTCCNSDCTLKEGVQCSDRNSPCCKN-CQFETAQKKC--QEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGR--------CVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQY 702          

Query:  176 KISFSTKFRKFKLILKPSVDLLSNDLKSVNIDRFGRETPVPIDGSQFYQGFVSGAEKSSVSAFLGNDKMLSINIILDDDIFQVEPLSRYVQNNS---SFIVYRYSDLKGNFTRGPKCFAKNISSFETNTTNSRQKRNVDAIISLP----------YINKDST----KKLCTIKLIADYRFHREHGRGEMGRTQHYLIELIDKINILFKSTDFVDSKNNKNSGYGFIINQILVHVE------------PTIGPSGHYNQEVAKQTDAWTVEGLLDSFGDIDHKDSCLAHLFTFQSFSEGTLGLAYMASSKTLSYGGICSERDFRHQNSKLVSVNTAWSTYRDAVGKRVISMSAYLVTAHELGHNWGADHDPDTTDCAPNAARG------GKYVMYTYSVVGYEPNNRLFSPCSRRSIGATIATRGEYCFLSPMNAFCGNSRVDDNEECDVGKNNS-ADACC-------TSDCHFKPGAVCSPNNHECCTNDCQFKPYGFVCAAKDPMNPCVNHSICSGKEKECLGPLSIDGPNCTEHGR----CSSGKCR-PYCEQLNMEACICDKIE-----ESCLICC---RDPPSKINSNTIQECRPAQNGIQSRLTLNQGRPC 1855
            ++ F    R F L +K    L S++ K    ++      +  D S  Y G + G E S     + + +     I      F VEP  RY+++ +     ++Y   D+      GP+    + S FE       Q   V+ +  +P           + K  T    K  C + +  D+ F + +G  E    Q  +   +  I+ ++++TDF   +N       F++ +I ++              P IG                 VE  L+   + +H D CLA++FT + F +G LGLA++ +  + S GGIC E+   + + K  S+NT   T ++  G  V    +++  AHE+GHN+G+ HD   T+C P  ++       G Y+MY  +  G + NN  FS CS R+I   +  +   CF+      CGN  V+  EECD G ++   D CC          C  KPG  CSP+   CCT  C FK     C  +D  + C    IC+G    C  P S   PN T+  R    C +G+C    CE+  +E C C   +     E C +CC    DP +  ++ ++Q  R         +TL  G PC
Sbjct:   61 RLDFHAHGRHFNLRMKRDTSLFSDEFKVETSNKV-----LDYDTSHIYTGHIYGEEGSFSHGSVIDGRFEGF-IQTRGGTFYVEPAERYIKDRTLPFHSVIYHEDDINYPHKYGPQGGCADHSVFER--MRKYQMTGVEEVTQIPQEEHAANGPELLRKKRTTSAEKNTCQLYIQTDHLFFKYYGTREAVIAQ--ISSHVKAIDTIYQTTDFSGIRN-----ISFMVKRIRINTTADEKDPTNPFRFPNIG-----------------VEKFLELNSEQNHDDYCLAYVFTDRDFDDGVLGLAWVGAP-SGSSGGIC-EKSKLYSDGKKKSLNTGIITVQN-YGSHVPPKVSHITFAHEVGHNFGSPHD-SGTECTPGESKNLGQKENGNYIMYARATSGDKLNNNKFSLCSIRNISQVLEKKRNNCFVESGQPICGNGMVEQGEECDCGYSDQCKDECCFDANQPEGRKCKLKPGKQCSPSQGPCCTAQCAFKSKSEKC--RDDSD-CAREGICNGFTALC--PASDPKPNFTDCNRHTQVCINGQCAGSICEKYGLEECTCASSDGKDDKELCHVCCMKKMDPSTCASTGSVQWSRHFSG---RTITLQPGSPC 632          

Query:  947 AHLFTFQSFSEGTLGLAYMASSKTLSYGGICSERDFRHQNSKLVSVNTAWSTYRDAVGKRVISMSAYLVTAHELGHNWGADHDPDTTDCA-PNAARGGKYVMYTYSVVGYEPNNRLFSPCSRRSIGATIATRGEYCF------LSPMNAFCGNSRVDDNEECDVG-KNNSADACCTS-DCHFKPGAVCSPNNHECCTNDCQFKPYGFVCAAKDPMNPCVNHSICSGKEKECLGPLSI-DGPNCT-EHGRCSSGKCRPYCEQ 1696
            A L T  SFS  T+G+A   S        ICS  DF         VN   ST    V   +         AHELGH+ G DHD     C  P  A     +M   +   + P    FS CSRR++   +      C       L PM AFCGN  V+  E+CD G  ++  D CC S  C  +PGA C+ ++  CC N CQ +P G+ C  +     C     C G   +C   +S+ DG  C      C  G+C  Y +Q
Sbjct:  285 AQLVTGTSFSGPTVGMAIQNS--------ICSP-DFSG------GVNMDHSTSILGVASSI---------AHELGHSLGLDHDLPGNSCPCPGPAPAKTCIMEAST--DFLPGLN-FSNCSRRALEKALLDGMGSCLFERLPSLPPMAAFCGNMFVEPGEQCDCGFLDDCVDPCCDSLTCQLRPGAQCA-SDGPCCQN-CQLRPSGWQC--RPTRGDCDLPEFCPGDSSQCPPDVSLGDGEPCAGGQAVCMHGRCASYAQQ 514          

Query:  947 AHLFTFQSFSEGTLGLAYMASSKTLSYGGICSERDFRHQNSKLVSVNTAWSTYRDAVGKRVISMSAYLVTAHELGHNWGADHDPDTTDCA-PNAARGGKYVMYTYSVVGYEPNNRLFSPCSRRSIGATIATRGEYCF------LSPMNAFCGNSRVDDNEECDVG-KNNSADACCTS-DCHFKPGAVCSPNNHECCTNDCQFKPYGFVCAAKDPMNPCVNHSICSGKEKECLGPLSI-DGPNCT-EHGRCSSGKCRPYCEQ 1696
            A L T  SFS  T+G+A   S        ICS  DF         VN   ST    V   +         AHELGH+ G DHD     C  P  A     +M   +   + P    FS CSRR++   +      C       L PM AFCGN  V+  E+CD G  ++  D CC S  C  +PGA C+ ++  CC N CQ +P G+ C  +     C     C G   +C   +S+ DG  C      C  G+C  Y +Q
Sbjct:  301 AQLVTGTSFSGPTVGMAIQNS--------ICSP-DFSG------GVNMDHSTSILGVASSI---------AHELGHSLGLDHDLPGNSCPCPGPAPAKTCIMEAST--DFLPGLN-FSNCSRRALEKALLDGMGSCLFERLPSLPPMAAFCGNMFVEPGEQCDCGFLDDCVDPCCDSLTCQLRPGAQCA-SDGPCCQN-CQLRPSGWQC--RPTRGDCDLPEFCPGDSSQCPPDVSLGDGEPCAGGQAVCMHGRCASYAQQ 530          

Query:  947 AHLFTFQSFSEGTLGLAYMASSKTLSYGGICSERDFRHQNSKLVSVNTAWSTYRDAVGKRVISMSAYLVTAHELGHNWGADHDPDTTDCA-PNAARGGKYVMYTYSVVGYEPNNRLFSPCSRRSIGATIATRGEYCF------LSPMNAFCGNSRVDDNEECDVG-KNNSADACCTS-DCHFKPGAVCSPNNHECCTNDCQFKPYGFVCAAKDPMNPCVNHSICSGKEKECLGPLSI-DGPNCT-EHGRCSSGKCRPYCEQ 1696
            A L T  SFS  T+G+A   S        ICS  DF         VN   ST    V   +         AHELGH+ G DHD     C  P  A     +M   +   + P    FS CSRR++   +      C       L PM AFCGN  V+  E+CD G  ++  D CC S  C  +PGA C+ ++  CC N CQ +P G+ C  +     C     C G   +C   +S+ DG  C      C  G+C  Y +Q
Sbjct:  301 AQLVTGTSFSGPTVGMAIQNS--------ICSP-DFSG------GVNMDHSTSILGVASSI---------AHELGHSLGLDHDLPGNSCPCPGPAPAKTCIMEAST--DFLPGLN-FSNCSRRALEKALLDGMGSCLFERLPSLPPMAAFCGNMFVEPGEQCDCGFLDDCVDPCCDSLTCQLRPGAQCA-SDGPCCQN-CQLRPSGWQC--RPTRGDCDLPEFCPGDSSQCPPDVSLGDGEPCAGGQAVCMHGRCASYAQQ 530          

Query:  632 CTIKLIADYRFHREHGRGEMGRTQHYLIELIDKINILFKSTDFVDSKNNKNSG------YGFIINQILVHVEPTIGPSGHYNQEVAKQTDAWTVEGLLDSFGDID-HKDSCLAHLFTFQSFSE-GTLGLAYMASSK-TLSYGGICSERDFRHQNSKLVSVNTAWSTY---RDAVGKRVISMSAYLVTAHELGHNWGADHDP-------DTTDCAPNAARGGKYVMYTYSVVGYEPNNRLFSPCSRRSIGATIATRGEYCFLSPMNAFCGNSRVDDNEECDVGKNNSADA-CCTSDCHFKPGAVCSPNNHECCTNDCQFKPYGFVCAAKDPMNPCVNHSICSGKEKEC-LGPLSIDGPNCTEHGRCSSGKCRPYCEQLNM--EACICDKIEESCLICCRDPPSKINSNTIQECRPAQNGIQSRLTLNQGRPCALGVCEEGVCKRRVNKLVERI 1918
            CT+KL+ADY F+   G+   G    +L+ +I ++N ++   ++   K +  SG       GF I +I V   P    S HYN      +  W VE LL  F   +  KD CL HL T ++F E  TLGLAY++  K   + GGICS+++    N ++  +N   ST     +     +I+    +V +HE GH WGA HDP       D  +C+PN   GGKY+M  Y+  GY+ NN LFSPCSR+ I   +  + E CF   M +FCGN  V+D EECD G +   +  CC   C    GA CSP NH CCT  CQF     VC   D +  C   ++C+G   EC   P   DG  C E G C +G C P+CE++++  ++CIC+ +E SC +CCRD            C P    +   + L  G  C+ G C +  C   VN++V+ +
Sbjct:  189 CTLKLVADYSFYSIFGKNNTGIVTKFLVNMIARVNEIYTPINWDVGKEDDISGRGRFQNMGFSIKEIKVLDRPNASDS-HYNS----YSRIWEVERLLREFAFAEGSKDFCLVHLVTARTFREVATLGLAYVSYKKWDETAGGICSKQE--TFNGRVAYINVLLSTSFANSEQSTYPLITKEIDIVVSHEYGHAWGATHDPTIDSDDPDVEECSPNDQNGGKYLMSQYAQKGYDANNVLFSPCSRKLIRDVLIGKWESCFQEEMTSFCGNGIVEDGEECDNGVDTDNEFNCCDKFCRLAVGAKCSPLNHICCTPTCQFHNSTHVCLPGDSL-LCKADAVCNGFSGECPSAPPVRDGQECLEGGECLNGVCLPFCEKMSIGKKSCICEDLELSCRLCCRDYNGT--------CAP----VPGHVYLRDGVRCSKGSCRDRKC---VNEVVDNV 617          

Query:  626 KLCTIKLIADYRFHREHGRGEMG-----RTQHYLIEL----IDKINILFKSTDFVDSKNNKNSGYGFIINQILVHVEPTIGPSGHYNQEVAKQ--TDAWTVEGLLDSFGDIDHKDSCLAHLFTFQSFSEGTLGLAYMASSKTLSYGGICSERDFRHQNSK---LVSVNTAWSTYRDAVGKRVISMSAYLVTAHELGHNWGADHDPDTTDCAPNAARGGKYVMYTYSVVGYEPNNRLFSPCSRRSIGATIA----------TRG--------EYCFLSPMNAFCGNSRVDDNEECDVGKNNS-----ADACCT----------SDCHFKPGAVCSPNNHECCTND-CQF--KPYGFVCAAKDPMNPCVNHSICSGKEKEC-LGPLSIDGPNCTEHGR-CSSGKCR-PYCEQLNMEACIC--DKIEESCLICC 1753
            + C++ + AD++ + EH R + G     RT+  ++ L    I  +N +++ T+F     N   G  F+I +  ++  P     G    +       +   V   L+     +H   CLA+  TF+ F  GTLGLA++AS +  + GGIC      ++ S+     S+NT   T  +  G RV +  + L  AHE+GHN+G+ HD    +C P     G ++M+  +  G +PNN  FSPCS ++I A +A          TR           CF    +AFCGN   +  EECD G + +      D CC             C  KPGA CSP+   CC  D C    K    +C  +   + C N   C G+  +C + P   DG  C +  + CSSG+C    C    +E C     K +E C + C
Sbjct:  242 RTCSLYMQADHKLY-EHIRMKEGNNDPIRTREEIVSLFYNHIKAVNEIYEGTNF-----NGIKGLHFVIQRTSIYT-PDSCDRGRAKTDSDNPFCEENVDVSNFLNLNSQRNHSAFCLAYALTFRDFVGGTLGLAWVASPQFNTAGGICQVHQRYNEGSRGWVYRSLNTGIVTLVN-YGNRVPARVSQLTLAHEIGHNFGSPHD-FPAECQPGLP-DGNFIMFASATSGDKPNNGKFSPCSVKNISAVLAVVLKSMPVDPTRNASPVGIGKRNCFQERTSAFCGNQIYEPGEECDCGFSQADCDQMGDKCCVPHEARGNGGPGPCKRKPGAQCSPSQGYCCNPDTCSLHGKNEEKICRQE---SECSNLQTCDGRNAQCPVSPPKHDGIPCQDSTKVCSSGQCNGSVCAMFGLEDCFLTEGKADELCFLAC 659          

Query:  188 STKFRKFKLILKPSVDLLSNDLKSVNIDRFGRETPVPIDGSQFYQGFVSGAEKSSVSAFLGNDKMLSINIILDDDIFQVEPLSRYVQNNSSFIVYRYSDLKGNFTRGPKCFAKNISSFETNTTNSRQKRNVDAIISLPYI---NKDSTK--KLCTIKLIADYRFHREHGRGEMGRTQHYLIELIDKINILFKSTDFVDSKNNKNSGYGFIINQILVHVEPTIGPSGHYNQEVAKQTDAW-----TVEGLLD-SFGDIDHKDSCLAHLFTFQSFSEGTLGLAYMASSKTLSYGGICSERDFRHQNSKLVSVNTAWSTYRDAVGKRVISMSAYLVTAHELGHNWGADHDPDTTDCAPNAARGGKYVMYTYSVVGYEPNNRLFSPCSRRSIGATIATRGEYCFLS-PMNAF----CGNSRVDDNEECDVG-KNNSADACCTS-DCHFKPGAVCSPNNHECCTNDCQFKPYGFVCAAKDPMNPCVNHSICSGKEKECL--GPLSIDGPNCTEHGRCSSGKC 1678
            S +  + KL+L+ +  +  N      +D  G         + +YQG V G E+SS  A    + +  +    +   F + PL    +N+       Y   K  +++  KC     SS        R K++V    S  +     +D +K  K   + LIADY F +  G           +  +D I+ + +S +  DS  +++      I    V+VE              ++ D W     T+ G++D + G I H     + LFT  SF+   +  A + S        IC+ R     ++ +V     ++T+ +             + A  +GH  G +HD     C P+     +         G  P +  FS CS   +          C L+ P        CGN  VD +EECD G + N  D CC    C  +P A C+  +H+CC + C+ +  G  C  +   +PC     C GK  +C   G L IDG  C   G+C  G C
Sbjct:   84 SNQLGRLKLVLERNNFIFLNQTAFHKLDADGERVIQNRVENCYYQGTV-GGEESSFVALSSCNGLRGVISFANGTTFGIWPLDGGDRNSRRHPHILY---KSEWSQEAKCG----SSMAHAVGQRRMKKHVHKHRSHHHEHNKKRDVSKRTKYVEVALIADYEFMKARG-----------LHDLDAISYMLESLNIADSMLSRD----LNIRLSAVYVELWTD---------VQRIDLWEDIERTLSGVVDYASGHIYHIQKDASILFTAGSFANQEVSNAAIRS--------ICTAR-----SAVIVKGVEQFATHWNGE-----------LLAQSIGHLLGLEHDTTACSCEPSPECVMRQQPGRVGGGGGSPFSWQFSKCSVARMHGIWQDGNIQCLLNKPFQVSELRECGNGVVDGSEECDCGSRENCQDPCCDPLTCTLRPHAQCAA-HHKCC-HRCELRKAGDTC--RSSKSPCDVAEQCDGKSGDCPPDGHL-IDGTVCGTDGQCWRGNC 539          

Query:  449 NNSSFIVYRYSDLKGNFTRGPKCFAKNISSFETNTTNSRQKRNVDAIISLPYINKDSTKKLCTIKLIADYRFHREHGRGEMGRTQHYLIELIDKINILFKSTDFVDSKNNKNSGYGFIINQILVHVEPTIGPSGHYNQEVAKQTDAWTVEGLLDSFGDIDHKDSCL--AHLFTFQSFSEGTLGLAYMASSKTLSY-GGICSERDFRHQNSKLVSVNTAWSTYRDAVGKRVISMSAYLVTAHELGHNWGADHDPDTTDCAPNAARGGKYVMYTYSVVGYEPNN-RLFSPCSRRSIGATIATRGEYCFLS-----PMNAFCGNSRVDDNEECDVGKNNSADACCT-SDCHFKPGAVCSPNNHECC-TNDCQFKPYGFVCAAKDPMNPCVNHSICSGKEKEC 1612
            NN SF++  Y  ++ N   G    + +    +    N+   RN   I      + D  K+   + L+ADY  + ++   E  +   Y+ + ++ +N L+               +   I   LVH E  I   G    +++   D+         +  I  KD      +L T   F EG +G AY  +  +  Y GGI  +    H N  + +V T                      AHELGH +G DHDP+  D          Y      ++  +  +  ++S CS +++ +      + C  +     P +A CGN  V+  EECD G     + CC  S C     A C+  + +CC    C+ KP   VC A   +  C     C+G+  +C
Sbjct:  124 NNGSFVLIPY--VENNCDLGSLVHSSSRKKRQIGKQNTVIDRNPSYIRE----HLDGRKRFVELALVADYSVYTKYDSDEK-KVNDYMQQTMNILNSLY---------------FPLNIRITLVHSE--IWKKG---DQISVIPDSKETLNNFMEYKKIMLKDHFFDTGYLMTTLKFDEGVVGKAYKGTMCSYDYSGGIYVD----HNNDTVETVATF---------------------AHELGHTFGMDHDPNDKDVC--------YCPMPRCIMNPQSGHMEVWSECSVKNLASGFNRGIDLCLFNEPGKKPSDAKCGNGIVEPGEECDCGPLKCDNHCCNGSTCKLIGEAECA--SGDCCDLKTCKPKPRATVCRAA--IGICDLDEYCNGETNDC 458          

Query:  449 NNSSFIVYRYSDLKGNFTRGPKCFAKNISSFETNTTNSRQKRNVDAIISLPYINKDSTKKLCTIKLIADYRFHREHGRGEMGRTQHYLIELIDKINILFKSTDFVDSKNNKNSGYGFIINQILVHVEPTIGPSGHYNQEVAKQTDAWTVEGLLDSFGDIDHKDSCL--AHLFTFQSFSEGTLGLAYMASSKTLSY-GGICSERDFRHQNSKLVSVNTAWSTYRDAVGKRVISMSAYLVTAHELGHNWGADHDPDTTDCAPNAARGGKYVMYTYSVVGYEPNN-RLFSPCSRRSIGATIATRGEYCFLS-----PMNAFCGNSRVDDNEECDVGKNNSADACCT-SDCHFKPGAVCSPNNHECC-TNDCQFKPYGFVCAAKDPMNPCVNHSICSGKEKEC 1612
            NN SF++  Y  ++ N   G    + +    +    N+   RN   I      + D  K+   + L+ADY  + ++   E  +   Y+ + ++ +N L+               +   I   LVH E  I   G    +++   D+         +  I  KD      +L T   F EG +G AY  +  +  Y GGI  +    H N  + +V T                      AHELGH +G DHDP+  D          Y      ++  +  +  ++S CS +++ +      + C  +     P +A CGN  V+  EECD G     + CC  S C     A C+  + +CC    C+ KP   VC A   +  C     C+G+  +C
Sbjct:  124 NNGSFVLIPY--VENNCDLGSLVHSSSRKKRQIGKQNTVIDRNPSYIRE----HLDGRKRFVELALVADYSVYTKYDSDEK-KVNDYMQQTMNILNSLY---------------FPLNIRITLVHSE--IWKKG---DQISVIPDSKETLNNFMEYKKIMLKDHFFDTGYLMTTLKFDEGVVGKAYKGTMCSYDYSGGIYVD----HNNDTVETVATF---------------------AHELGHTFGMDHDPNDKDVC--------YCPMPRCIMNPQSGHMEVWSECSVKNLASGFNRGIDLCLFNEPGKKPSDAKCGNGIVEPGEECDCGPLKCDNHCCNGSTCKLIGEAECA--SGDCCDLKTCKPKPRATVCRAA--IGICDLDEYCNGETNDC 458          

Query:  173 KKISFSTKFRKFKLILKPSVDLLSNDLKSVNIDRFGRETPVPIDGSQFYQGFVSGAEKSSVSAFLGNDKMLSINIILDDDIFQVEPLSRYV--QNNSSFIVYRYSDLK-------------GNFTRGPKCFAKNISSFETNTTNSRQKRNVDAIISLPYINKDSTKKLCTIKLIADYRFHREHGRGEMGRTQHYLIELIDKINILFKSTDFVDSKNNKN-SGYGFIINQILVHVEPTI--GPSGHYNQEVAKQTDAWTVEGLLDSFG-DIDHKDSCLAHLFTFQSFSEGTLGLAYMASSKTLSYGGICSERDFRHQNSKLVSVNTAWSTYRDAVGKRVISMSAYLVTAHELGHNWGADHDPDTTDCAPNAARGGKYVMYTYSVVGYEPNNRLFSPCSRRSIGATIATRGEYCFLSPMNAFCGNSRVDDNEECDVG--KNNSADACCTSDCHFK--PGAVCSPNNHECCTNDCQFKPYGFVCAAKDPMNPCVNHSICSGKEKEC-LGPLSIDGPNCTEHGRCSSGKCRPYCEQLNMEACICDKIEESCLICCRDPPSKINSNTIQECRPAQNGIQSRLTLNQGRPCALGVCEEGVCKRRVNKLVERIWKIIDEFNTNLFAAFLLENXXXXXXXXXXXXXXPAAILVSCNDAKHRRRFLQ 2074
            K++ F+T  + F+LIL P  D+L +  ++  +D  G ET V +D   FY G V G  +SSV A +  D  ++++I L ++ + +EP  R++      + + Y+ SD+K             G    G +   K       N  ++R+KR  D     P      TK  C + L+ADYRF +E G G    T +YLI LID+++ ++  T + D  + +   G GF+I +I+VH EPT   G   HYN    K    W V  LL+ F  +  HKD CLAHLFT   F  G LGLAY+ S +  S GGIC+   F+  N   + +N+  S+ R+  G+RVI+  A LVTAHE GHNWG++HDPD  +C+P+A++GG ++MYTYSV GY+ NN+ FSPCS RSI   +  +   CF  P  +FCGN RV+ +E+CD G       D+CC  +C  +   GA+CS  N  CC N CQF   G  C        C   + C+G   EC   P   DG  C E G+C +GKC PYCE   +++C+CD I ++C  CCR     IN    + C P    ++    L  G PC  G C +GVC++ +  +VER W II+E N      FL +N+V  V+++T + WIP + ++S  D K  R  ++
Sbjct:   64 KEVEFTTLGKNFRLILHPHRDVLHSKFRAYAVDADGNETVVHMDHDSFYSGRVFGELESSVRAHI-EDGTMTMSIHLPEETYHIEPSWRHLPEAKKDTMVAYKASDVKVHKNEAGATPKTCGYIKEGLELEDKEHGDTLDNELHTREKRQSDQYEYTP------TKTRCPLLLVADYRFFQEMGGGNTKTTINYLISLIDRVHKIYNDTVWQDRSDQEGFKGMGFVIKKIVVHSEPTRLRGGEAHYNMIREK----WDVRNLLEVFSREYSHKDFCLAHLFTDLKFEGGILGLAYVGSPRRNSVGGICTPEYFK--NGYTLYLNSGLSSSRNHYGQRVITREADLVTAHEFGHNWGSEHDPDIPECSPSASQGGSFLMYTYSVSGYDVNNKKFSPCSLRSIRKVLQAKSGRCFSEPEESFCGNLRVEGDEQCDAGLLGTEDNDSCCDKNCKLRRNQGAMCSDKNSPCCQN-CQFMASGMKCREAQ-YATCEQEARCTGAHAECPKSPAMADGTTCQERGQCRNGKCVPYCETQGLQSCMCDIIADACKRCCR---MSIN----ETCFP----VEPPDVLPDGTPCITGFCNKGVCEKTIQDVVERFWDIIEEINVAKTLRFLKDNIVMAVVLVTAVFWIPISCVISYFDRKKLRHEMK 695          

Query:  554 TNSRQKRNVDAIISLPYINKDSTKKLCTIKLIADYRFHREHGRGEMGRTQHYLIELIDKINILFKSTDFVDSKNNKNSGYGFIINQILVH-----VEPTIGPSGHYNQEVAKQTDAWTVEGLLDSFGDIDHKDSCLAHLFTFQSFSEGTLGLAYMASSKTLSYGGICSERDFRHQNSKLVSVNTAWSTYRDAVGKRVISMSAYLVTAHELGHNWGADHDPDTTDCAPNAARGGKYVMYTYSVVGYEPNNRLFSPCSRRSIGATIATRGEY---CFLSPMNAFCGNSRVDDNEECDVG-KNNSADACC----------TSDCHFKPGAVCSPNNHECCTNDCQFKPYGFVCAAKDPMNPCVNHSICSGKEKECLGPLSIDGPN---CTEHGRCSSGKCR-PYCEQLNMEACIC------DKIEESCLICCRDP 1762
            TN    R  + I S P +  D  K  C + L AD+ F ++ G  E   +   +   + + N ++++TDF  + + K     F+I +I VH      +P+    G+Y            VE  L+ F + D+   CLA++FT++ F  GTLGLA+    K  + GG+C +    H    L S+NT   T  +  GK V    +++  AHE+GHN+G+ HDP+   C P     G ++M+  +  G + NN  FS CS +SI   +  +      CF  P ++ CGN  V+  E+CD G + +  D+CC           + C   P A CSP+   CCT DC+ K +G  C      N C + S C G+  +C  P S++ PN   C +   C  G C    C    +E+C C      D+I +SC +CC+ P
Sbjct:  456 TNLLSGRGGEDIHSSPRLLYDR-KTTCMLYLQADHTFFQKMGSDEA--SIEAITRHVQRANTIYRNTDF--NNDGKPDNITFMIKRIKVHNMNAMKDPSYRFPGNYG-----------VEKFLELFSEEDYDAFCLAYMFTYRDFEMGTLGLAWTGDLK--NAGGVCEKNG--HYRGSLKSLNTGIVTLLN-YGKHVPPAVSHVTLAHEIGHNFGSPHDPE--QCTP-GGEDGNFIMFARATSGDKKNNNKFSTCSLKSIEPVLNAKARSMKGCFTEPQSSICGNGVVEPGEQCDCGWEEDCKDSCCFPMSRQPRLDETPCTLTPHARCSPSQGPCCTTDCKLK-FGDKCRDD---NGCRDPSFCDGRVPQC--PPSVNKPNKTICNKEFVCYMGDCTGSICLAYGLESCQCIPGPQDDRI-KSCELCCKLP 856          

Query:  554 TNSRQKRNVDAIISLPYINKDSTKKLCTIKLIADYRFHREHGRGEMGRTQHYLIELIDKINILFKSTDFVDSKNNKNSGYGFIINQILVH-----VEPTIGPSGHYNQEVAKQTDAWTVEGLLDSFGDIDHKDSCLAHLFTFQSFSEGTLGLAYMASSKTLSYGGICSERDFRHQNSKLVSVNTAWSTYRDAVGKRVISMSAYLVTAHELGHNWGADHDPDTTDCAPNAARGGKYVMYTYSVVGYEPNNRLFSPCSRRSIGATIATRGEY---CFLSPMNAFCGNSRVDDNEECDVG-KNNSADACC----------TSDCHFKPGAVCSPNNHECCTNDCQFKPYGFVCAAKDPMNPCVNHSICSGKEKECLGPLSIDGPN---CTEHGRCSSGKCR-PYCEQLNMEACIC------DKIEESCLICCRDP 1762
            TN    R  + I S P +  D  K  C + L AD+ F ++ G  E   +   +   + + N ++++TDF  + + K     F+I +I VH      +P+    G+Y            VE  L+ F + D+   CLA++FT++ F  GTLGLA+    K  + GG+C +    H    L S+NT   T  +  GK V    +++  AHE+GHN+G+ HDP+   C P     G ++M+  +  G + NN  FS CS +SI   +  +      CF  P ++ CGN  V+  E+CD G + +  D+CC           + C   P A CSP+   CCT DC+ K +G  C      N C + S C G+  +C  P S++ PN   C +   C  G C    C    +E+C C      D+I +SC +CC+ P
Sbjct:  456 TNLLSGRGGEDIHSSPRLLYDR-KTTCMLYLQADHTFFQKMGSDEA--SIEAITRHVQRANTIYRNTDF--NNDGKPDNITFMIKRIKVHNMNAMKDPSYRFPGNYG-----------VEKFLELFSEEDYDAFCLAYMFTYRDFEMGTLGLAWTGDLK--NAGGVCEKNG--HYRGSLKSLNTGIVTLLN-YGKHVPPAVSHVTLAHEIGHNFGSPHDPE--QCTP-GGEDGNFIMFARATSGDKKNNNKFSTCSLKSIEPVLNAKARSMKGCFTEPQSSICGNGVVEPGEQCDCGWEEDCKDSCCFPMSRQPRLDETPCTLTPHARCSPSQGPCCTTDCKLK-FGDKCRDD---NGCRDPSFCDGRVPQC--PPSVNKPNKTICNKEFVCYMGDCTGSICLAYGLESCQCIPGPQDDRI-KSCELCCKLP 856          

Query:  554 TNSRQKRNVDAIISLPYINKDSTKKLCTIKLIADYRFHREHGRGEMGRTQHYLIELIDKINILFKSTDFVDSKNNKNSGYGFIINQILVH-----VEPTIGPSGHYNQEVAKQTDAWTVEGLLDSFGDIDHKDSCLAHLFTFQSFSEGTLGLAYMASSKTLSYGGICSERDFRHQNSKLVSVNTAWSTYRDAVGKRVISMSAYLVTAHELGHNWGADHDPDTTDCAPNAARGGKYVMYTYSVVGYEPNNRLFSPCSRRSIGATIATRGEY---CFLSPMNAFCGNSRVDDNEECDVG-KNNSADACC----------TSDCHFKPGAVCSPNNHECCTNDCQFKPYGFVCAAKDPMNPCVNHSICSGKEKECLGPLSIDGPN---CTEHGRCSSGKCR-PYCEQLNMEACIC------DKIEESCLICCRDP 1762
            TN    R  + I S P +  D  K  C + L AD+ F ++ G  E   +   +   + + N ++++TDF  + + K     F+I +I VH      +P+    G+Y            VE  L+ F + D+   CLA++FT++ F  GTLGLA+    K  + GG+C +    H    L S+NT   T  +  GK V    +++  AHE+GHN+G+ HDP+   C P     G ++M+  +  G + NN  FS CS +SI   +  +      CF  P ++ CGN  V+  E+CD G + +  D+CC           + C   P A CSP+   CCT DC+ K +G  C      N C + S C G+  +C  P S++ PN   C +   C  G C    C    +E+C C      D+I +SC +CC+ P
Sbjct:  456 TNLLSGRGGEDIHSSPRLLYDR-KTTCMLYLQADHTFFQKMGSDEA--SIEAITRHVQRANTIYRNTDF--NNDGKPDNITFMIKRIKVHNMNAMKDPSYRFPGNYG-----------VEKFLELFSEEDYDAFCLAYMFTYRDFEMGTLGLAWTGDLK--NAGGVCEKNG--HYRGSLKSLNTGIVTLLN-YGKHVPPAVSHVTLAHEIGHNFGSPHDPE--QCTP-GGEDGNFIMFARATSGDKKNNNKFSTCSLKSIEPVLNAKARSMKGCFTEPQSSICGNGVVEPGEQCDCGWEEDCKDSCCFPMSRQPRLDETPCTLTPHARCSPSQGPCCTTDCKLK-FGDKCRDD---NGCRDPSFCDGRVPQC--PPSVNKPNKTICNKEFVCYMGDCTGSICLAYGLESCQCIPGPQDDRI-KSCELCCKLP 856          

Query:  647 IADYRFHREHGRGEMGRTQ--HYLIELIDKINILFKSTDFVDSKNNKNSGYGFIINQILVHVEPTIGPS--GHYNQEVAKQTDAWTVEGLLDSFGDIDHKDSCLAHLFTFQSFSEGTLGLAYMASSKTLSYGGICSERDF-------RHQNSKLVSVNTAWSTYRDAVGKRVISMSAYLVTAHELGHNWGADHDPDTTDCAPNAARGGKYVMYTYSVVGYEPNNRLFSPCSRRSIG----ATIATRGEYCFLSPMNAFCGNSRVDDNEECDVGKNNS--ADACC---------------TSDCHFKPGAVCSPNNHECC-TNDCQFKPYGFVCAAKDPMNPCVNHSICSGKEKECLGPLSIDGPNCTEHGR--CSSGKCRPY-CEQLNMEACICDKI-------EESCLICCRDPPSKINSNTIQECRPAQNGIQSRLTLNQGRPC 1855
            IAD+   R++   E  R +    +   +  +N ++++T F     ++N    F + +I +  +     S  G +N    +  D   V   L+     DH D CLA++FT++ F+ GTLGLA++AS+   S GGIC +          ++Q++K  S+NT   T+ +    RV    + L  AHE+GHN+G+ HD    +C P     G Y+M+  +  G  PNN  FSPCS R+I       +      CF +   AFCGN  V+  EECD G N     D CC                  C  +    CSP+   CC +N C F P  +    K+    C   S C+G   EC  P   D      +G   C  G+C    C   NM  C             + C + C+D        +  E     N  +  ++L  G PC
Sbjct:  430 IADHDRGRKYEVDEKTREEITSLIAHHVTAVNYIYRNTKFDGRTEHRN--IRFEVQRIKIDDDSACRNSYNGPHNAFCNEHMD---VSNFLNLHSLEDHSDFCLAYVFTYRDFTGGTLGLAWVASASGAS-GGICEKYKTYTETVGGQYQSTKR-SLNTGIITFVN-YNSRVPPKVSQLTLAHEIGHNFGSPHDY-PQECRPGGL-NGNYIMFASATSGDRPNNSKFSPCSIRNISNVLDVLVGNTKRDCFKASEGAFCGNKIVESGEECDCGFNEEECKDKCCYPRLISEYDQSLNSSAKGCTRRAKTQCSPSQGPCCLSNSCTFVPTSYHQKCKEETE-CSWSSTCNGTTAECPEPRHRDDKTMCNNGTALCIRGECSGSPCLLWNMTKCFLTSTTLPHVSKRKLCDLACQDGNDTSTCRSTSEFADKYNIQKGGISLQPGSPC 864          

Query:  110 LSDYDILPNLNIR--------ISRSTFDNKKISFSTKFRKFKLILKPSVDLLSNDLKSVNIDRFGRETPVPIDGSQFYQGFVSGAEKSSVSAFLGNDKMLSINIILDDDIFQVEPLSRYVQN--NSSFIVYRYSDLKGNFTRGPKC-----FAKNISSFETNTTNSRQKRNVDAIISLPYINKDSTKKLCTIKLIADYRFHREHGRGEMGRTQHYLIELIDKINILFKSTDFVDSKNNKNSGYGFIINQILVHVEPT-IGPSG-HYNQEVAKQTD--AWTVEGLLDSFGDIDHKDS----CLAHLFTFQSFSEGTLGLAYMASSKTLSYGGICSER-DFRHQNSKLVSVNTAWSTYRDAVGKRVISMSAYLVTAHELGHNWGADHDPDTTD-CAPNAARGGKYVMYTYSVVGYEPNNRLFSPCSRRSIGATIATRGEYCFLSPMNAFCGNSRVDDNEECDVG-KNNSADACCTSDCHFKPGAVCSPNNHECCTNDCQFKPYGFVCAAKDPMNP-CVNHSICSGKEKECLGPLSIDGPN---CTEHGRCSSGKCRPYCEQL-NMEACICDKIEESCLICCRDPPSKINSNTIQECRPAQNGIQSRLTLNQGRPCALGVCE-EGVCKRRVNKLVERIWKIIDEFNTNLFAAFLLENXXXXXXXXXXXXXXPAAILVSCNDAKHRRRF 2068
            LSD+D+L   +++        +   T   + + F+   R FKL L  + +L ++D K+V +   G +    +    F+ G V G E S V A +G D   + +I+ D+  + +EPL R+ +N  +S  +VYR  D++ N +R          + + S     +   R++R             D +K  C + L+ADYRF +  GR E   T +YLIELID+++ ++++T + D    +  GYG  I QI++++ PT + P G H+N +     D   W V+ LL+ F  ID  D+    CLAHLFT+Q F EGTLGLAY+A SK    GG+CSE+      +++ + +NT  ++ ++  GK +++  A LVT HELGHN+GA HDPD    CAP   +GGKYVMY  +V G   NN+LFS CS+ SI   +  +   CF    +  CGNSRV++ EECD G  + ++D CCT++C  KPG  CS  N  CC  DC+F+    VC  ++PM   C   S CSG   EC  P ++  PN   C ++GRC +G+C P+CE + N+++C C++   SC +CC+D       N +  C P      S L L +G+PC +G C+  G C ++V  ++ER+W  I++ + N F  FL +N+VG+V++ +L+ WIP +ILV C D K  +++
Sbjct:   30 LSDFDVLQLSSLQQHSVRKRDVQSQTHAERLLGFTALQRHFKLYLTTNTELFTHDFKAVVVGEDGAQEVYEVQRENFFTGHVIGEENSRVQAHIG-DNDFTAHILTDEAEYNIEPLWRFTENTHDSRLLVYRSEDIR-NVSRLAATKVCGYVSADASEVLPESVRVRERRQT----------VDHSKNTCPLLLVADYRFFKHMGRKEESTTLNYLIELIDRVDDIYRNTSWDD----EYKGYGVQIQQIIINMTPTQVEPGGAHFNMKGTPVKDKYVWDVKKLLEQFS-IDIADNASQVCLAHLFTYQDFDEGTLGLAYVAPSKPGFPGGLCSEKCPPSGNDNRAIYLNTGLTSTKN-YGKTILTKEADLVTTHELGHNFGAVHDPDDMSYCAPREDQGGKYVMYPIAVSGDHTNNKLFSNCSKMSIAKRLRAKASTCFKERNSNVCGNSRVEEGEECDPGLLHLNSDLCCTANCKLKPGVQCSDRNSPCC-KDCRFEKQNKVC--QEPMEATCKGRSNCSGYGSECPPPENL--PNKTICVDNGRCLNGECIPFCEAVKNLQSCACNETHNSCKVCCKD------KNGV--CAPYIGDKGSPLFLRKGKPCTVGFCDGAGKCMKQVQDVIERLWDFIEKLDINTFGKFLADNIVGSVVVFSLLFWIPLSILVHCVDKKLDQQY 683          

Query:   89 FGDWQNQLSDYDILPNLNIRI--------SRSTFDNKKISFSTKFRKFKLILKPSVDLLSNDLKSVNIDRFGRETPVPIDGSQFYQGFVSGAEKSSVSAFLGNDKMLSINIILDDDIFQVEPLSRYVQN--NSSFIVYRYSDLKGNFTR--GPK-CFAKNISSFETNTTNSRQKRNVDAIISLPY-----INKDSTKKLCTIKLIADYRFHREHGRGEMGRTQHYLIELIDKINILFKSTDFVDSKNNKNSGYGFIINQILVHVEPTIGPSG--HYNQE---VAKQTDAWTVEGLLDSFG-DI--DHKDSCLAHLFTFQSFSEGTLGLAYMASSKTLSYGGICSERDFRHQNSKLVSVNTAWSTYRDAVGKRVISMSAYLVTAHELGHNWGADHDPDT-TDCAPNAARGGKYVMYTYSVVGYEPNNRLFSPCSRRSIGATIATRGEYCFLSPMNAFCGNSRVDDNEECDVG-KNNSADACCTSDCHFKPGAVCSPNNHECCTNDCQFKPYGFVCAAKDPMNPCVNHSICSGKEKECLGPLSI-DGPNCTEHGRCSSGKCRPYCEQL-NMEACICDKIEESCLICCRDPPSKINSNTIQECRPAQNGIQSRLTLNQGRPCALGVCE-EGVCKRRVNKLVERIWKIIDEFNTNLFAAFLLENXXXXXXXXXXXXXXPAAILVSCNDAKHRRRFLQERKSRRPEVFENFS 2116
            F    + LSD+++LP   +++           +   + +SF+   R FKL L  +  L + +  +V +D  G+E    +    +++G V G E S V A +  D+  S +II ++  + VEPL R+ +   +   +VYR  D+K N +R   PK C   N  + E     +R    ++ +   P+        D  K  CT+ L+AD+RF++  GR E   T +YLIELID+++ ++++T + D       GYG  I QI+++ +PT    G  HYN +     ++   W V+ LL+ F  DI  +   +CLAHLFT+Q F +GTLGLAY+A SK    GG+C +  +  Q+ K  S      T     GK +++  A LVT HELGHN+GA+HDPD    CAP+  +GGKYVMY  +V G   NN+ FS CS+ S+  T+  +   CF+   +  CGNSRV+++E+CD G  + + D CCTS+C F+  A CS  N  CC N C F+    VC        C   S C+G   EC  P ++ D   C + GRC +G+CRP+CE + N+E+C C++ E SC +CCR           + C P  NG  S L L +G+PC +G C+  G C ++V  ++ER+W  ID+ N N F  FL +N+VG+V++ +L+ WIP +ILV C D +   ++ +  K   P   E  S
Sbjct:   38 FDALNSLLSDFEVLPASGLQLHSVRKRDADAHSHVERLVSFTALQRNFKLYLTTNTQLFTENFSAVFVDENGKEDQFDVQIQNYFKGHVVGEEHSRVQAHIDGDE-FSAHIITEETEYNVEPLWRFTETPPDGRLLVYRSEDIK-NISRLSSPKVCGYVNADAQELLPEEARAAEEMEEMKEEPHNRERRSTHDQKKNTCTLLLVADHRFYKHMGRAEESTTLNYLIELIDRVDDIYRNTSWDDDFK----GYGVQIQQIIINKDPTKVAPGEFHYNMDGSPTGRKDGVWDVKKLLEQFSYDIAANASRACLAHLFTYQDFDDGTLGLAYVAPSKP-GLGGLCPKPYYPSQSVKKPSYLNTGLTSTMNYGKTILTKEADLVTTHELGHNFGAEHDPDNIASCAPSDDQGGKYVMYPIAVSGDHVNNKHFSTCSKISVSKTLRIKVNQCFVERSSKLCGNSRVEEDEDCDPGLLHINDDPCCTSNCKFRKQAQCSDRNSPCCKN-CMFESADKVCQEVITAT-CKGTSQCTGNSSECPTPGNLEDNTECVDKGRCQNGQCRPFCEAVHNLESCACNETENSCKVCCRKD---------ELCTPFLNG-GSFLYLRKGKPCTVGFCDGAGKCMKQVQDVIERLWDFIDKLNINTFGKFLADNIVGSVVVFSLLFWIPISILVHCVDKRLDEQYEENTKMMYPSSGEILS 725          

Query:  110 LSDYDILPNLNIR--------ISRSTFDNKKISFSTKFRKFKLILKPSVDLLSNDLKSVNIDRFGRETPVPIDGSQFYQGFVSGAEKSSVSAFLGNDKMLSINIILDDDIFQVEPLSRYVQN--NSSFIVYRYSDLK--GNFTRGPKCFAKNISSFETNTTNSRQKRNVD-------AIISLPYINKDSTKKLCTIKLIADYRFHREHGRGEMGRTQHYLIELIDKINILFKSTDFVDSKNNKNSGYGFIINQILVHVEPT-IGPSG-HYNQEVAKQTD--AWTVEGLLDSFGDIDHKDS----CLAHLFTFQSFSEGTLGLAYMASSKTLSYGGICSER-DFRHQNSKLVSVNTAWSTYRDAVGKRVISMSAYLVTAHELGHNWGADHDPDTTD-CAPNAARGGKYVMYTYSVVGYEPNNRLFSPCSRRSIGATIATRGEYCFLSPMNAFCGNSRVDDNEECDVG-KNNSADACCTSDCHFKPGAVCSPNNHECCTNDCQFKPYGFVCAAKDPMNP-CVNHSICSGKEKECLGPLSIDGPN---CTEHGRCSSGKCRPYCEQL-NMEACICDKIEESCLICCRDPPSKINSNTIQECRPAQNGIQSRLTLNQGRPCALGVCE-EGVCKRRVNKLVERIWKIIDEFNTNLFAAFLLENXXXXXXXXXXXXXXPAAILVSCNDAKHRRRF 2068
            LSD+D+L   +++        +   T   + + F+   R FKL L  + +L ++D K+V +   G +    +    F+ G V G E S V A +G D   + +I+ D+  + +EPL R+ +N  +S  +VYR  D++          C   +  + E    + R  R +D         +       D +K  C + L+ADYRF +  GR E   T +YLIELID+++ ++++T + D    +  GYG  I QI++++ PT + P G H+N +     D   W V+ LL+ F  ID  D+    CLAHLFT+Q F EGTLGLAY+A SK    GG+CSE+      +++ + +NT  ++ ++  GK +++  A LVT HELGHN+GA HDPD    CAP   +GGKYVMY  +V G   NN+LFS CS+ SI   +  +   CF    +  CGNSRV++ EECD G  + ++D CCT++C  KPG  CS  N  CC  DC+F+    VC  ++PM   C   S CSG   EC  P ++  PN   C ++GRC +G+C P+CE + N+++C C++   SC +CC+D       N +  C P      S L L +G+PC +G C+  G C ++V  ++ER+W  I++ + N F  FL +N+VG+V++ +L+ WIP +ILV C D K  +++
Sbjct:   36 LSDFDVLQLSSLQQHSVRKRDVQSQTHAERLLGFTALQRHFKLYLTTNTELFTHDFKAVVVGEDGAQEVYEVQRENFFTGHVIGEENSRVQAHIG-DNDFTAHILTDEAEYNIEPLWRFTENTHDSRLLVYRSEDIRNVSRLAATKVCGYVSADASEVLPESVRVSRALDEDHQEEEGQVRERRQTVDHSKNTCPLLLVADYRFFKHMGRKEESTTLNYLIELIDRVDDIYRNTSWDD----EYKGYGVQIQQIIINMTPTQVEPGGAHFNMKGTPVKDKYVWDVKKLLEQFS-IDIADNASQVCLAHLFTYQDFDEGTLGLAYVAPSKPGFPGGLCSEKCPPSGNDNRAIYLNTGLTSTKN-YGKTILTKEADLVTTHELGHNFGAVHDPDDMSYCAPREDQGGKYVMYPIAVSGDHTNNKLFSNCSKMSIAKRLRAKASTCFKERNSNVCGNSRVEEGEECDPGLLHLNSDLCCTANCKLKPGVQCSDRNSPCC-KDCRFEKQNKVC--QEPMEATCKGRSNCSGYGSECPPPENL--PNKTICVDNGRCLNGECIPFCEAVKNLQSCACNETHNSCKVCCKD------KNGV--CAPYIGDKGSPLFLRKGKPCTVGFCDGAGKCMKQVQDVIERLWDFIEKLDINTFGKFLADNIVGSVVVFSLLFWIPLSILVHCVDKKLDQQY 704          

Query:   89 FGDWQNQLSDYDILPNLNIRI--------SRSTFDNKKISFSTKFRKFKLILKPSVDLLSNDLKSVNIDRFGRETPVPIDGSQFYQGFVSGAEKSSVSAFLGNDKMLSINIILDDDIFQVEPLSRYVQN--NSSFIVYRYSDLKGNFTR--GPK-CFAKNISSFETNTTNSRQKRNVDAIISLPY-----INKDSTKKLCTIKLIADYRFHREHGRGEMGRTQHYLIELIDKINILFKSTDFVDSKNNKNSGYGFIINQILVHVEPTIGPSG--HYNQE---VAKQTDAWTVEGLLDSFG-DI--DHKDSCLAHLFTFQSFSEGTLGLAYMASSKTLSYGGICSERDFRHQNSKLVSVNTAWSTYRDAVGKRVISMSAYLVTAHELGHNWGADHDPDT-TDCAPNAARGGKYVMYTYSVVGYEPNNRLFSPCSRRSIGATIATRGEYCFLSPMNAFCGNSRVDDNEECDVG-KNNSADACCTSDCHFKPGAVCSPNNHECCTNDCQFKPYGFVCAAKDPMNPCVNHSICSGKEKECLGPLSI-DGPNCTEHGRCSSGKCRPYCEQL-NMEACICDKIEESCLICCRDPPSKINSNTIQECRPAQNGIQSRLTLNQGRPCALGVCE-EGVCKRRVNKLVERIWKIIDEFNTNLFAAFLLENXXXXXXXXXXXXXXPAAILVSCNDAKHRRRFLQERKSRRP 2095
            F    + LSD+++LP   +++           +   + +SF+   R FKL L  +  L + +  +V +D  G+E    +    +++G V G E S V A +  D+  S +II ++  + VEPL R+ +   +   +VYR  D+K N +R   PK C   N  + E     +R    ++ +   P+        D  K  CT+ L+AD+RF++  GR E   T +YLIELID+++ ++++T + D       GYG  I QI+++ +PT    G  HYN +     ++   W V+ LL+ F  DI  +   +CLAHLFT+Q F +GTLGLAY+A SK    GG+C +  +  Q+ K  S      T     GK +++  A LVT HELGHN+GA+HDPD    CAP+  +GGKYVMY  +V G   NN+ FS CS+ S+  T+  +   CF+   +  CGNSRV+++E+CD G  + + D CCTS+C F+  A CS  N  CC N C F+    VC        C   S C+G   EC  P ++ D   C + GRC +G+CRP+CE + N+E+C C++ E SC +CCR           + C P  NG  S L L +G+PC +G C+  G C ++V  ++ER+W  ID+ N N F  FL +N+VG+V++ +L+ WIP +ILV C D +   ++ +  K   P
Sbjct:   38 FDALNSLLSDFEVLPASGLQLHSVRKRDADAHSHVERLVSFTALQRNFKLYLTTNTQLFTENFSAVFVDENGKEDQFDVQIQNYFKGHVVGEEHSRVQAHIDGDE-FSAHIITEETEYNVEPLWRFTETPPDGRLLVYRSEDIK-NISRLSSPKVCGYVNADAQELLPEEARAAEEMEEMKEEPHNRERRSTHDQKKNTCTLLLVADHRFYKHMGRAEESTTLNYLIELIDRVDDIYRNTSWDDD----FKGYGVQIQQIIINKDPTKVAPGEFHYNMDGSPTGRKDGVWDVKKLLEQFSYDIAANASRACLAHLFTYQDFDDGTLGLAYVAPSKP-GLGGLCPKPYYPSQSVKKPSYLNTGLTSTMNYGKTILTKEADLVTTHELGHNFGAEHDPDNIASCAPSDDQGGKYVMYPIAVSGDHVNNKHFSTCSKISVSKTLRIKVNQCFVERSSKLCGNSRVEEDEDCDPGLLHINDDPCCTSNCKFRKQAQCSDRNSPCCKN-CMFESADKVCQEVITAT-CKGTSQCTGNSSECPTPGNLEDNTECVDKGRCQNGQCRPFCEAVHNLESCACNETENSCKVCCRKD---------ELCTPFLNG-GSFLYLRKGKPCTVGFCDGAGKCMKQVQDVIERLWDFIDKLNINTFGKFLADNIVGSVVVFSLLFWIPISILVHCVDKRLDEQYEENTKMMYP 718          

Query:  116 DYDILPNLNIRISRSTFDNKK---ISFSTKFRKFKLILKPSVDLLSNDLKSVNIDRFGRETPVPIDGSQFYQGFVSGAEKSSVSAFLGNDKMLSINIILDDDIFQVEPLSRYVQN-NSSF--IVYRYSDLKGNFTRGPKCFAKNISSFETNTT-----NSRQKRNVDAIISLPYINKDSTKKLCTIKLIADYRFHREHGRGEMGRTQHYLIELIDKINILFKSTDFVDSKNNKNSGYGFIINQILVHVEPTIGPSGHYNQEVAKQTDAWTVEGLLDSFGDIDHKDSCLAHLFTFQSFSEGTLGLAYMASSKTLSYGGICSERDFRHQNSKLVSVNTAWSTYRDAVGKRVISMSAYLVTAHELGHNWGADHDPDTTDCAPNAARG------GKYVMYTYSVVGYEPNNRLFSPCSRRSIGATIATRGEYCFLSPMNAFCGNSRVDDNEECDVGKNNS-ADACC-------TSDCHFKPGAVCSPNNHECCTNDCQFKPYGFVCAAKDPMNPCVNHSICSGKEKECLGPLSIDGPNCTE-HGR---CSSGKCR-PYCEQLNMEACICDKIE-----ESCLICCRD 1759
            D ++L + + R  R+    ++   + F    R F L ++    L ++D K   ++  G+E  +  D S  Y G + G E+ +++     D      I+     F VEP+ RY+Q+ N  F  ++Y   D+    T  P+  +  +             +S   ++ D ++    + +   K  C + +  D+ F++ +   E    Q  +   +  I+ +++ TDF+  +N       F++ +I ++       S   ++    +     VE  L+   + +H D CLA++FT + F +G LGLA++ +    S GGIC E++  + + K  S+NT   T ++     V    +++  AHE+GHN+G+ HD   ++C P  ++       G Y+MY  +  G + NN  FS CS ++I   +  +   CF+      CGN  V+  E+CD G ++   D CC          C  KPG VCSP+   CCT +C +K +   C  +   + C +  +CSG   +C  P S    N T  HG    C +G C    CE+  +E C C  +E     E C +CC +
Sbjct:   46 DTEMLHSDHQRAKRAATHTERTLQLEFHAHGRHFNLRMRRDTGLFADDFK---LEVSGQE--MDYDTSHIYSGEIYG-EQGTLTHGSVQDGRFEGFILTHRGTFYVEPVERYLQDKNVPFHSVIYHEDDIV-THTAVPRSSSNAVPPAHLPPLDLLLQDSPPAQDEDVLLRKKRMTQ-VEKNTCQLFIQTDHLFYKYYKTREAVIAQ--ISSHVKAIDAIYQGTDFMGIRN-----ISFMVKRIRINT-----TSDERDRSNPFRFANIGVEKFLELNSEQNHDDYCLAYVFTDRDFDDGVLGLAWVGAPAGSS-GGIC-EKNKLYSDGKKKSLNTGIITVQN-YASHVPPKVSHITFAHEVGHNFGSPHD-SGSECTPGESKSPDKKERGNYIMYARATSGDKLNNNKFSVCSIKNISQVLEKKRGSCFVESGQPICGNGLVEPGEQCDCGYSDQCKDDCCYDANQPDNKKCKLKPGKVCSPSQGPCCTFECSYKGHNEKCREE---SECAHQGLCSGSSAQC--PTSEPKANFTACHGNTQVCLNGGCSGSICEKYGLEVCTCASVEGKDETELCHVCCME 599          

Query:  110 LSDYDILPNLNIR--------ISRSTFDNKKISFSTKFRKFKLILKPSVDLLSNDLKSVNIDRFGRETPVPIDGSQFYQGFVSGAEKSSVSAFLGNDKMLSINIILDDDIFQVEPLSRYVQNNS--SFIVYRYSDLKGNFTR----------GPKCFAKNISSFETNTTNSRQKRNVDAIISLPYINKDSTKKLCTIKLIADYRFHREHGRGEMGRTQHYLIELIDKINILFKSTDFVDSKNNKNSGYGFIINQILVHVEPTIGPSG--HYNQEVA---KQTDAWTVEGLLDSFG-DIDHKDS--CLAHLFTFQSFSEGTLGLAYMASSKTLSYGGICSERDFRHQNSKLVSVNTAWSTYRDAVGKRVISMSAYLVTAHELGHNWGADHDPDTTD-CAPNAARGGKYVMYTYSVVGYEPNNRLFSPCSRRSIGATIATRGEYCFLSPMNAFCGNSRVDDNEECDVG-KNNSADACCTSDCHFKPGAVCSPNNHECCTNDCQFKPYGFVCAAKDPMNP-CVNHSICSGKEKECLGPLSIDGPN-CTEHGRCSSGKCRPYCE-QLNMEACICDKIEESCLICCRDPPSKINSNTIQECRPAQNGIQSRLTLNQGRPCALGVCE-EGVCKRRVNKLVERIWKIIDEFNTNLFAAFLLENXXXXXXXXXXXXXXPAAILVSCNDAKHRRRFLQERKS 2086
            LS+YD+L   +I+        +   +   + +SF+   R FKL L  S +L+S +L+++ +D  G+E    +  S F+ G V G   S V A +G D   +  I  D + + +EPL R+V+N S  + +VYR  D+K +F+R           PK   +++   E +T  S +  +            DS +  C + ++AD+RF +  GRGE   T +YLIELID+++ ++++T +    NN+  GYG  I QI+VH EP     G  HYN   A      DAW V+ LL+ F  DI  K +  CLAHLFT+Q F  GTLGLAY+ S K  ++GGIC +      + K V +NT  ++ ++  GK +++  A LVT HELGHN+G++HDPD+ + CAP+   GGK+VMY  +V G   NN++FS CSR SI  T+  +   CF    N  CGNSRVD+ EECD G  +   D CCTSDC F+PG  CS  N  CC   CQF+     C  ++ +N  C   S C+G   EC  P + +    C + G+C +G+CRP+CE + N+++C C+  E SC +CCRD       N +  C P ++     L L +G+PC +G C+  G C+++V  ++ERIW  ID+ + N+F  FL +N+VG+V++ +L+ WIP +ILV C D K  +R+ +  KS
Sbjct:   11 LSEYDVLSLSSIQQHSLRKRDLQSQSQLERMLSFTALQRHFKLYLTSSTELVSENLEALVLDGNGKEKKYQVKWSDFFTGHVVGEHNSKVLAHIG-DGDFTARITTDGEEYNIEPLWRFVENTSGDNMLVYRSGDIK-DFSRLKSSKVCGYIKPK---EDLFKNEQDTAESAEGDDYLHREKRQRAGPDSLRNTCKMLVVADHRFFKYMGRGEESTTINYLIELIDRVDDIYRNTSW---DNNQWKGYGVQIEQIIVHKEPENVTQGQKHYNMARAFPNPDKDAWDVKQLLEQFSYDISEKAAQVCLAHLFTYQDFDMGTLGLAYVGSHKPNTHGGICPKAYENDLSKKAVYLNTGLTSTKN-YGKTILTKEADLVTTHELGHNFGSEHDPDSMEACAPSEDHGGKFVMYPIAVSGDHENNKMFSSCSRESILRTLMAKSPICFKERNNKVCGNSRVDEGEECDPGLLHQHNDPCCTSDCKFQPGVHCSDRNSPCCRG-CQFESAQKKC--QEAINATCKGESYCTGSSSECPTPGNAENDTVCVDLGKCVNGECRPFCEIERNLKSCACNDTENSCKVCCRD------ENGV--CSPQKDQHDHFLYLRKGKPCTVGFCDANGKCEKQVQDVIERIWDFIDKLSINMFGKFLADNIVGSVVVFSLLFWIPLSILVHCVDKKLDKRYEETTKS 683          

Query:  110 LSDYDILPNLNIR--------ISRSTFDNKKISFSTKFRKFKLILKPSVDLLSNDLKSVNIDRFGRETPVPIDGSQFYQGFVSGAEKSSVSAFLGNDKMLSINIILDDDIFQVEPLSRYVQNNS--SFIVYRYSDLKGNFTR--GPKCFAKNISSFETNTTNSRQKRNVDAIISLPYINKDSTKKLCTIKLIADYRFHREHGRGEMGRTQHYLIELIDKINILFKSTDFVDSKNNKNSGYGFIINQILVHVEPTIGPSG--HYNQEVA---KQTDAWTVEGLLDSFG-DIDHKDS--CLAHLFTFQSFSEGTLGLAYMASSKTLSYGGICSERDFRHQNSKLVSVNTAWSTYRDAVGKRVISMSAYLVTAHELGHNWGADHDPDTTD-CAPNAARGGKYVMYTYSVVGYEPNNRLFSPCSRRSIGATIATRGEYCFLSPMNAFCGNSRVDDNEECDVG-KNNSADACCTSDCHFKPGAVCSPNNHECCTNDCQFKPYGFVCAAKDPMNP-CVNHSICSGKEKECLGPLSIDGPN-CTEHGRCSSGKCRPYCE-QLNMEACICDKIEESCLICCRDPPSKINSNTIQECRPAQNGIQSRLTLNQGRPCALGVCE-EGVCKRRVNKLVERIWKIIDEFNTNLFAAFLLENXXXXXXXXXXXXXXPAAILVSCNDAKHRRRFLQERKS 2086
            LS+YD+L   +I+        +   +   + +SF+   R FKL L  S +L+S +L+++ +D  G+E    +  S F+ G V G   S V A +G D   +  I  D + + +EPL R+V+N S  + +VYR  D+K +F+R    K   K       +    R+KR             DS +  C + ++AD+RF +  GRGE   T +YLIELID+++ ++++T +    NN+  GYG  I QI+VH EP     G  HYN   A      DAW V+ LL+ F  DI  K +  CLAHLFT+Q F  GTLGLAY+ S K  ++GGIC +      + K V +NT  ++ ++  GK +++  A LVT HELGHN+G++HDPD+ + CAP+   GGK+VMY  +V G   NN++FS CSR SI  T+  +   CF    N  CGNSRVD+ EECD G  +   D CCTSDC F+PG  CS  N  CC   CQF+     C  ++ +N  C   S C+G   EC  P + +    C + G+C +G+CRP+CE + N+++C C+  E SC +CCRD       N +  C P ++     L L +G+PC +G C+  G C+++V  ++ERIW  ID+ + N+F  FL +N+VG+V++ +L+ WIP +ILV C D K  +R+ +  KS
Sbjct:   54 LSEYDVLSLSSIQQHSLRKRDLQSQSQLERMLSFTALQRHFKLYLTSSTELVSENLEALVLDGNGKEKKYQVKWSDFFTGHVVGEHNSKVLAHIG-DGDFTARITTDGEEYNIEPLWRFVENTSGDNMLVYRSGDIK-DFSRLKSSKVCGKITLWLGGDDYLHREKRQ--------RAGPDSLRNTCKMLVVADHRFFKYMGRGEESTTINYLIELIDRVDDIYRNTSW---DNNQWKGYGVQIEQIIVHKEPENVTQGQKHYNMARAFPNPDKDAWDVKQLLEQFSYDISEKAAQVCLAHLFTYQDFDMGTLGLAYVGSHKPNTHGGICPKAYENDLSKKAVYLNTGLTSTKN-YGKTILTKEADLVTTHELGHNFGSEHDPDSMEACAPSEDHGGKFVMYPIAVSGDHENNKMFSSCSRESILRTLMAKSPICFKERNNKVCGNSRVDEGEECDPGLLHQHNDPCCTSDCKFQPGVHCSDRNSPCCRG-CQFESAQKKC--QEAINATCKGESYCTGSSSECPTPGNAENDTVCVDLGKCVNGECRPFCEIERNLKSCACNDTENSCKVCCRD------ENGV--CSPQKDQHDHFLYLRKGKPCTVGFCDANGKCEKQVQDVIERIWDFIDKLSINMFGKFLADNIVGSVVVFSLLFWIPLSILVHCVDKKLDKRYEETTKS 713          

Query:  110 LSDYDILPNLNIR--------ISRSTFDNKKISFSTKFRKFKLILKPSVDLLSNDLKSVNIDRFGRETPVPIDGSQFYQGFVSGAEKSSVSAFLGNDKMLSINIILDDDIFQVEPLSRYVQNNS--SFIVYRYSDLKGNFTR----------GPKCFAKNISSFETNTTNSRQKRNVDAIISLPYINKDSTKKLCTIKLIADYRFHREHGRGEMGRTQHYLIELIDKINILFKSTDFVDSKNNKNSGYGFIINQILVHVEPTIGPSG--HYNQEVA---KQTDAWTVEGLLDSFG-DIDHKDS--CLAHLFTFQSFSEGTLGLAYMASSKTLSYGGICSERDFRHQNSKLVSVNTAWSTYRDAVGKRVISMSAYLVTAHELGHNWGADHDPDTTD-CAPNAARGGKYVMYTYSVVGYEPNNRLFSPCSRRSIGATIATRGEYCFLSPMNAFCGNSRVDDNEECDVG-KNNSADACCTSDCHFKPGAVCSPNNHECCTNDCQFKPYGFVCAAKDPMNP-CVNHSICSGKEKECLGPLSIDGPN-CTEHGRCSSGKCRPYCE-QLNMEACICDKIEESCLICCRDPPSKINSNTIQECRPAQNGIQSRLTLNQGRPCALGVCE-EGVCKRRVNKLVERIWKIIDEFNTNLFAAFLLENXXXXXXXXXXXXXXPAAILVSCNDAKHRRRFLQERKS 2086
            LS+YD+L   +I+        +   +   + +SF+   R FKL L  S +L+S +L+++ +D  G+E    +  S F+ G V G   S V A +G D   +  I  D + + +EPL R+V+N S  + +VYR  D+K +F+R           PK   +++   E +T  S +  +            DS +  C + ++AD+RF +  GRGE   T +YLIELID+++ ++++T +    NN+  GYG  I QI+VH EP     G  HYN   A      DAW V+ LL+ F  DI  K +  CLAHLFT+Q F  GTLGLAY+ S K  ++GGIC +      + K V +NT  ++ ++  GK +++  A LVT HELGHN+G++HDPD+ + CAP+   GGK+VMY  +V G   NN++FS CSR SI  T+  +   CF    N  CGNSRVD+ EECD G  +   D CCTSDC F+PG  CS  N  CC   CQF+     C  ++ +N  C   S C+G   EC  P + +    C + G+C +G+CRP+CE + N+++C C+  E SC +CCRD       N +  C P ++     L L +G+PC +G C+  G C+++V  ++ERIW  ID+ + N+F  FL +N+VG+V++ +L+ WIP +ILV C D K  +R+ +  KS
Sbjct:   21 LSEYDVLSLSSIQQHSLRKRDLQSQSQLERMLSFTALQRHFKLYLTSSTELVSENLEALVLDGNGKEKKYQVKWSDFFTGHVVGEHNSKVLAHIG-DGDFTARITTDGEEYNIEPLWRFVENTSGDNMLVYRSGDIK-DFSRLKSSKVCGYIKPK---EDLFKNEQDTAESAEGDDYLHREKRQRAGPDSLRNTCKMLVVADHRFFKYMGRGEESTTINYLIELIDRVDDIYRNTSW---DNNQWKGYGVQIEQIIVHKEPENVTQGQKHYNMARAFPNPDKDAWDVKQLLEQFSYDISEKAAQVCLAHLFTYQDFDMGTLGLAYVGSHKPNTHGGICPKAYENDLSKKAVYLNTGLTSTKN-YGKTILTKEADLVTTHELGHNFGSEHDPDSMEACAPSEDHGGKFVMYPIAVSGDHENNKMFSSCSRESILRTLMAKSPICFKERNNKVCGNSRVDEGEECDPGLLHQHNDPCCTSDCKFQPGVHCSDRNSPCCRG-CQFESAQKKC--QEAINATCKGESYCTGSSSECPTPGNAENDTVCVDLGKCVNGECRPFCEIERNLKSCACNDTENSCKVCCRD------ENGV--CSPQKDQHDHFLYLRKGKPCTVGFCDANGKCEKQVQDVIERIWDFIDKLSINMFGKFLADNIVGSVVVFSLLFWIPLSILVHCVDKKLDKRYEETTKS 693          

Query:  173 KKISFSTKFRKFKLILKPSVDLLSNDLKSVNIDRFGRETPVPIDGSQFYQGFVSGAEKSSVSAFLGNDKMLSINIILDDDIFQVEPLSRYVQNNS--SFIVYRYSDLKGNFTRGPKC-FAKNISSFETNTTNSRQKRNVDAIISLPYINKDSTKKLCTIKLIADYRFHREHGRGEMGRTQHYLIELIDKINILFKSTDFVDSKNNKNSGYGFIINQILVHVEPTIGPSG--HYNQEVA---KQTDAWTVEGLLDSFG-DIDHKDS--CLAHLFTFQSFSEGTLGLAYMASSKTLSYGGICSERDFRHQNSKLVSVNTAWSTYRDAVGKRVISMSAYLVTAHELGHNWGADHDPDTTD-CAPNAARGGKYVMYTYSVVGYEPNNRLFSPCSRRSIGATIATRGEYCFLSPMNAFCGNSRVDDNEECDVG-KNNSADACCTSDCHFKPGAVCSPNNHECCTNDCQFKPYGFVCAAKDPMNP-CVNHSICSGKEKECLGPLSIDGPN-CTEHGRCSSGKCRPYCE-QLNMEACICDKIEESCLICCRDPPSKINSNTIQECRPAQNGIQSRLTLNQGRPCALGVCE-EGVCKRRVNKLVERIWKIIDEFNTNLFAAFLLENXXXXXXXXXXXXXXPAAILVSCNDAKHRRRFLQERKS 2086
            + +SF+   R FKL L  S +L+S +L+++ +D  G+E    +  S F+ G V G   S V A +G D   +  I  D + + +EPL R+V+N S  + +VYR  D+K +F+R         I   E    N +        +       DS +  C + ++AD+RF +  GRGE   T +YLIELID+++ ++++T +    NN+  GYG  I QI+VH EP     G  HYN   A      DAW V+ LL+ F  DI  K +  CLAHLFT+Q F  GTLGLAY+ S K  ++GGIC +      + K V +NT  ++ ++  GK +++  A LVT HELGHN+G++HDPD+ + CAP+   GGK+VMY  +V G   NN++FS CSR SI  T+  +   CF    N  CGNSRVD+ EECD G  +   D CCTSDC F+PG  CS  N  CC   CQF+     C  ++ +N  C   S C+G   EC  P + +    C + G+C +G+CRP+CE + N+++C C+  E SC +CCRD       N +  C P ++     L L +G+PC +G C+  G C+++V  ++ERIW  ID+ + N+F  FL +N+VG+V++ +L+ WIP +ILV C D K  +R+ +  KS
Sbjct:   20 RMLSFTALQRHFKLYLTSSTELVSENLEALVLDGNGKEKKYQVKWSDFFTGHVVGEHNSKVLAHIG-DGDFTARITTDGEEYNIEPLWRFVENTSGDNMLVYRSGDIK-DFSRLKSSKVCGYIKPKEDLFKNEQDTAESAEAVQRQRAGPDSLRNTCKMLVVADHRFFKYMGRGEESTTINYLIELIDRVDDIYRNTSW---DNNQWKGYGVQIEQIIVHKEPENVTQGQKHYNMARAFPNPDKDAWDVKQLLEQFSYDISEKAAQVCLAHLFTYQDFDMGTLGLAYVGSHKPNTHGGICPKAYENDLSKKAVYLNTGLTSTKN-YGKTILTKEADLVTTHELGHNFGSEHDPDSMEACAPSEDHGGKFVMYPIAVSGDHENNKMFSSCSRESILRTLMAKSPICFKERNNKVCGNSRVDEGEECDPGLLHQHNDPCCTSDCKFQPGVHCSDRNSPCCRG-CQFESAQKKC--QEAINATCKGESYCTGSSSECPTPGNAENDTVCVDLGKCVNGECRPFCEIERNLKSCACNDTENSCKVCCRD------ENGV--CSPQKDQHDHFLYLRKGKPCTVGFCDANGKCEKQVQDVIERIWDFIDKLSINMFGKFLADNIVGSVVVFSLLFWIPLSILVHCVDKKLDKRYEETTKS 657          

Query:  110 LSDYDILPNLNIR--------ISRSTFDNKKISFSTKFRKFKLILKPSVDLLSNDLKSVNIDRFGRETPVPIDGSQFYQGFVSGAEKSSVSAFLGNDKMLSINIILDDDIFQVEPLSRYVQNNS--SFIVYRYSDLKGNFTRGP------KCFAKNISSFET--NTTNSRQKRNVDAIISLPYINKDSTKKLCTIKLIADYRFHREHGRGEMGRTQHYLIELIDKINILFKSTDFVDSKNNKNSGYGFIINQILVHVEPTIGPSG--HYNQEVA---KQTDAWTVEGLLDSFG-DIDHKDS--CLAHLFTFQSFSEGTLGLAYMASSKTLSYGGICSERDFRHQNSKLVSVNTAWSTYRDAVGKRVISMSAYLVTAHELGHNWGADHDPDTTD-CAPNAARGGKYVMYTYSVVGYEPNNRLFSPCSRRSIGATIATRGEYCFLSPMNAFCGNSRVDDNEECDVG-KNNSADACCTSDCHFKPGAVCSPNNHECCTNDCQFKPYGFVCAAKDPMNP-CVNHSICSGKEKECLGPLSIDGPN-CTEHGRCSSGKCRPYCE-QLNMEACICDKIEESCLICCRDPPSKINSNTIQECRPAQNGIQSRLTLNQGRPCALGVCE-EGVCKRRVNKLVERIWKIIDEFNTNLFAAFLLENXXXXXXXXXXXXXXPAAILVSCNDAKHRRRFLQERKS 2086
            LS+YD+L   +I+        +   +   + +SF+   R FKL L  S +L+S +L+++ +D  G+E    +  S F+ G V G   S V A +G D   +  I  D + + +EPL R+V+N S  + +VYR  D+K +F+R        K F   I+      +    R+KR             DS +  C + ++AD+RF +  GRGE   T +YLIELID+++ ++++T +    NN+  GYG  I QI+VH EP     G  HYN   A      DAW V+ LL+ F  DI  K +  CLAHLFT+Q F  GTLGLAY+ S K  ++GGIC +      + K V +NT  ++ ++  GK +++  A LVT HELGHN+G++HDPD+ + CAP+   GGK+VMY  +V G   NN++FS CSR SI  T+  +   CF    N  CGNSRVD+ EECD G  +   D CCTSDC F+PG  CS  N  CC   CQF+     C  ++ +N  C   S C+G   EC  P + +    C + G+C +G+CRP+CE + N+++C C+  E SC +CCRD       N +  C P ++     L L +G+PC +G C+  G C+++V  ++ERIW  ID+ + N+F  FL +N+VG+V++ +L+ WIP +ILV C D K  +R+ +  KS
Sbjct:   21 LSEYDVLSLSSIQQHSLRKRDLQSQSQLERMLSFTALQRHFKLYLTSSTELVSENLEALVLDGNGKEKKYQVKWSDFFTGHVVGEHNSKVLAHIG-DGDFTARITTDGEEYNIEPLWRFVENTSGDNMLVYRSGDIK-DFSRLKSSKVCGKLFNHEINPIGLFCDDYLHREKRQ--------RAGPDSLRNTCKMLVVADHRFFKYMGRGEESTTINYLIELIDRVDDIYRNTSW---DNNQWKGYGVQIEQIIVHKEPENVTQGQKHYNMARAFPNPDKDAWDVKQLLEQFSYDISEKAAQVCLAHLFTYQDFDMGTLGLAYVGSHKPNTHGGICPKAYENDLSKKAVYLNTGLTSTKN-YGKTILTKEADLVTTHELGHNFGSEHDPDSMEACAPSEDHGGKFVMYPIAVSGDHENNKMFSSCSRESILRTLMAKSPICFKERNNKVCGNSRVDEGEECDPGLLHQHNDPCCTSDCKFQPGVHCSDRNSPCCRG-CQFESAQKKC--QEAINATCKGESYCTGSSSECPTPGNAENDTVCVDLGKCVNGECRPFCEIERNLKSCACNDTENSCKVCCRD------ENGV--CSPQKDQHDHFLYLRKGKPCTVGFCDANGKCEKQVQDVIERIWDFIDKLSINMFGKFLADNIVGSVVVFSLLFWIPLSILVHCVDKKLDKRYEETTKS 686          

Query:  110 LSDYDILPNLNIR--------ISRSTFDNKKISFSTKFRKFKLILKPSVDLLSNDLKSVNIDRFGRETPVPIDGSQFYQGFVSGAEKSSVSAFLGNDKMLSINIILDDDIFQVEPLSRYVQN--NSSFIVYRYSDLKGNFTR--GPK-CFAKNISSFETNTTNSRQKRNVDAIISLPYINK-------DSTKKLCTIKLIADYRFHREHGRGEMGRTQHYLIELIDKINILFKSTDFVDSKNNKNSGYGFIINQILVHVEPTIGPSGHYNQEVAK-----QTDAWTVEGLLDSFG-DIDHKDS--CLAHLFTFQSFSEGTLGLAYMASSKTLSYGGICSERDFRHQNSKLVSVNTAWSTYRDAVGKRVISMSAYLVTAHELGHNWGADHDPD-TTDCAPNAARGGKYVMYTYSVVGYEPNNRLFSPCSRRSIGATIATRGEYCFLSPMNAFCGNSRVDDNEECDVG---KNNSADACCTSDCHFKPGAVCSPNNHECCTNDCQFKPYGFVCAAKDPMNP-CVNHSICSGKEKECLGPLSI-DGPNCTEHGRCSSGKCRPYCE-QLNMEACICDKIEESCLICCRDPPSKINSNTIQECRPAQNGIQSRLTLNQGRPCALGVCE-EGVCKRRVNKLVERIWKIIDEFNTNLFAAFLLENXXXXXXXXXXXXXXPAAILVSCNDAKHRRRF 2068
            LSDYDIL   NI+        +  +T     ++FS   R FKL L  S +  S +L+ V +D    E+   +    F+ G V G   S V A +G+D  +++ I  D   + VEPL R+V +  +   +VY+  D+K +F+R   PK C   N  S E        K  +D   S  ++ +       +  K  C + ++AD+RF++  GRGE   T +YLIELID+++ ++++T +    N    GYG  I QI +   P     G  +  +AK     + DAW V+ LL+ F  DI  + S  CLAHLFT+Q F  GTLGLAY+ S +  S+GG+C +  +     K + +N+  ++ ++  GK +++  A LVT HELGHN+GA+HDPD   +CAPN  +GGKYVMY  +V G   NN++FS CS++SI  TI ++ + CF    N  CGNSRVD+ EECD G    NN  D CC SDC  KPG  CS  N  CC N CQF+     C  ++ +N  C   S C+G   EC  P    D   C + G+C +GKC P+C+ +  +E+C C   + SC +CCR        N    C P  +  Q  L L +G+PC +G C+  G C++RV  ++ER W  ID+ + N F  FL +N+VG+V++ +LI WIP +ILV C D K  +++
Sbjct:   39 LSDYDILSLANIQQHSIRKRDLQSATHLETLLTFSALKRHFKLYLTSSTERFSQNLRVVVVDG-KEESEYSVKWQNFFSGHVVGEPDSRVLAHIGDDD-VTVRINTDGAEYNVEPLWRFVNDTKDKRMLVYKSEDIK-DFSRLQSPKVCGYLNADSEEL-----LPKGLIDREPSEEFVRRVKRRAEPNPLKNTCKLLVVADHRFYKYMGRGEESTTTNYLIELIDRVDDIYRNTSW---DNAGFKGYGVQIEQIRILKSPQEVKPGERHFNMAKSFPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYNPTVKKNIYLNSGLTSTKN-YGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNN--DTCCNSDCTLKPGVQCSDRNSPCCKN-CQFETAQKKC--QEAINATCKGVSYCTGNSSECPPPGDAEDDTVCLDLGKCKAGKCIPFCKREQELESCACVDTDNSCKVCCR--------NLSGPCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQY 702          

Query:  110 LSDYDILPNLNIR--------ISRSTFDNKKISFSTKFRKFKLILKPSVDLLSNDLKSVNIDRFGRETPVPIDGSQFYQGFVSGAEKSSVSAFLGNDKMLSINIILDDDIFQVEPLSRYVQN--NSSFIVYRYSDLKGNFTR--GPK-CFAKNISSFETNTTNSRQKRNVDAIISLPYINK-------DSTKKLCTIKLIADYRFHREHGRGEMGRTQHYL-------------------IELIDKINILFKSTDFVDSKNNKNSGYGFIINQILVHVEPTIGPSGHYNQEVAK-----QTDAWTVEGLLDSFG-DIDHKDS--CLAHLFTFQSFSEGTLGLAYMASSKTLSYGGICSERDFRHQNSKLVSVNTAWSTYRDAVGKRVISMSAYLVTAHELGHNWGADHDPD-TTDCAPNAARGGKYVMYTYSVVGYEPNNRLFSPCSRRSIGATIATRGEYCFLSPMNAFCGNSRVDDNEECDVG---KNNSADACCTSDCHFKPGAVCSPNNHECCTNDCQFKPYGFVCAAKDPMNP-CVNHSICSGKEKECLGPLSI-DGPNCTEHGRCSSGKCRPYCE-QLNMEACICDKIEESCLICCRDPPSKINSNTIQECRPAQNGIQSRLTLNQGRPCALGVCE-EGVCKRRVNKLVERIWKIIDEFNTNLFAAFLLENXXXXXXXXXXXXXXPAAILVSCNDAKHRRRF 2068
            LSDYDIL   NI+        +  +T     ++FS   R FKL L  S +  S +L+ V +D    E+   +    F+ G V G   S V A +G+D  +++ I  D   + VEPL R+V +  +   +VY+  D+K +F+R   PK C   N  S E        K  +D   S  ++ +       +  K  C + ++AD+RF++  GRGE   T +YL                   IELID+++ ++++T +    N    GYG  I QI +   P     G  +  +AK     + DAW V+ LL+ F  DI  + S  CLAHLFT+Q F  GTLGLAY+ S +  S+GG+C +  +     K + +N+  ++ ++  GK +++  A LVT HELGHN+GA+HDPD   +CAPN  +GGKYVMY  +V G   NN++FS CS++SI  TI ++ + CF    N  CGNSRVD+ EECD G    NN  D CC SDC  KPG  CS  N  CC N CQF+     C  ++ +N  C   S C+G   EC  P    D   C + G+C +GKC P+C+ +  +E+C C   + SC +CCR        N    C P  +  Q  L L +G+PC +G C+  G C++RV  ++ER W  ID+ + N F  FL +N+VG+V++ +LI WIP +ILV C D K  +++
Sbjct:   39 LSDYDILSLANIQQHSIRKRDLQSATHLETLLTFSALKRHFKLYLTSSTERFSQNLRVVVVDG-KEESEYSVKWQNFFSGHVVGEPDSRVLAHIGDDD-VTVRINTDGAEYNVEPLWRFVNDTKDKRMLVYKSEDIK-DFSRLQSPKVCGYLNADSEEL-----LPKGLIDREPSEEFVRRVKRRAEPNPLKNTCKLLVVADHRFYKYMGRGEESTTTNYLGYISGTRDRVTTDCFLEFLIELIDRVDDIYRNTSW---DNAGFKGYGVQIEQIRILKSPQEVKPGERHFNMAKSFPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYNPTVKKNIYLNSGLTSTKN-YGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNN--DTCCNSDCTLKPGVQCSDRNSPCCKN-CQFETAQKKC--QEAINATCKGVSYCTGNSSECPPPGDAEDDTVCLDLGKCKAGKCIPFCKREQELESCACVDTDNSCKVCCR--------NLSGPCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQY 721          

Query:  110 LSDYDILPNLNIR--------ISRSTFDNKKISFSTKFRKFKLILKPSVDLLSNDLKSVNIDRFGRETPVPIDGSQFYQGFVSGAEKSSVSAFLGNDKMLSINIILDDDIFQVEPLSRYVQN--NSSFIVYRYSDLKGNFTR--GPK-CFAKNISSFETNTTNSRQKRNVDAIISLPYINK-------DSTKKLCTIKLIADYRFHREHGRGEMGRTQHYLIELIDKINILFKSTDFVDSKNNKNSGYGFIINQILVHVEPTIGPSGHYNQEVAK-----QTDAWTVEGLLDSFG-DIDHKDS--CLAHLFTFQSFSEGTLGLAYMASSKTLSYGGICSERDFRHQNSKLVSVNTAWSTYRDAVGKRVISMSAYLVTAHELGHNWGADHDPD-TTDCAPNAARGGKYVMYTYSVVGYEPNNRLFSPCSRRSIGATIATRGEYCFLSPMNAFCGNSRVDDNEECDVG---KNNSADACCTSDCHFKPGAVCSPNNHECCTNDCQFKPYGFVCAAKDPMNP-CVNHSICSGKEKECLGPLSI-DGPNCTEHGRCSSGKCRPYCE-QLNMEACICDKIEESCLICCRDPPSKINSNTIQECRPAQNGIQSRLTLNQGRPCALGVCE 1873
            LSDYDIL   NI+        +  +T     ++FS   R FKL L  S +  S +L+ V +D    E+   +    F+ G V G   S V A +G+D  +++ I  D   + VEPL R+V +  +   +VY+  D+K +F+R   PK C   N  S E        K  +D   S  ++ +       +  K  C + ++AD+RF++  GRGE   T +YLIELID+++ ++++T +    N    GYG  I QI +   P     G  +  +AK     + DAW V+ LL+ F  DI  + S  CLAHLFT+Q F  GTLGLAY+ S +  S+GG+C +  +     K + +N+  ++ ++  GK +++  A LVT HELGHN+GA+HDPD   +CAPN  +GGKYVMY  +V G   NN++FS CS++SI  TI ++ + CF    N  CGNSRVD+ EECD G    NN  D CC SDC  KPG  CS  N  CC N CQF+     C  ++ +N  C   S C+G   EC  P    D   C + G+C +GKC P+C+ +  +E+C C   + SC +CCR        N    C P  +  Q  L L +G+PC +G C+
Sbjct:   39 LSDYDILSLANIQQHSIRKRDLQSATHLETLLTFSALKRHFKLYLTSSTERFSQNLRVVVVDG-KEESEYSVKWQNFFSGHVVGEPDSRVLAHIGDDD-VTVRINTDGAEYNVEPLWRFVNDTKDKRMLVYKSEDIK-DFSRLQSPKVCGYLNADSEEL-----LPKGLIDREPSEEFVRRVKRRAEPNPLKNTCKLLVVADHRFYKYMGRGEESTTTNYLIELIDRVDDIYRNTSW---DNAGFKGYGVQIEQIRILKSPQEVKPGERHFNMAKSFPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYNPTVKKNIYLNSGLTSTKN-YGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNN--DTCCNSDCTLKPGVQCSDRNSPCCKN-CQFETAQKKC--QEAINATCKGVSYCTGNSSECPPPGDAEDDTVCLDLGKCKAGKCIPFCKREQELESCACVDTDNSCKVCCR--------NLSGPCVPYVDAEQKNLFLRKGKPCTVGFCD 636          

Query:  179 ISFSTKFRKFKLILKPSVDLLSNDLKSVNIDRFGRETPVPIDGSQFYQGFVSGAEKSSVSAFLGNDKMLSINIILDDDIFQVEPLSRYVQNNS---SFIVYRYSDLKGNFTRGPKCFAKNISSFETN--------TTNSRQKRNVDAIISLPYINKDSTKKL-----CTIKLIADYRFHREHGRGEMGRTQHYLIELIDKINILFKSTDFVDSKNNKNSGYGFIINQILVHVEPTIGPSGHYNQEVAKQTDAWTVEGLLDSFGDIDHKDSCLAHLFTFQSFSEGTLGLAYMASSKTLSYGGICSERDFRHQNSKLVSVNTAWSTYRDAVGKRVISMSAYLVTAHELGHNWGADHDPDTTDCAPNAARG------GKYVMYTYSVVGYEPNNRLFSPCSRRSIGATIATRGEYCFLSPMNAFCGNSRVDDNEECDVGKNNS-ADACC-------TSDCHFKPGAVCSPNNHECCTNDCQFKPYGFVCAAKDPMNPCVNHSICSGKEKECLGPLSIDGPNCTEHGR----CSSGKCR-PYCEQLNMEACICDKIE-----ESCLICCRDPPSKINSNTIQECRPAQNGIQSRLTLNQGRPC 1855
            + F    R+F L +K    L S++ K    ++      +  D S  Y G + G E S     + + +     I      F +EP  RY+++       ++Y   D+      GP+    + S FE             +R      A  S P + +     L     C + +  D+ F + +G  E    Q  +   +  I+ ++++TDF   +N       F++ +I ++       S   +     +     VE  L+   + +H D CLA++FT + F +G LGLA++ +  + S GGIC E+   + + K  S+NT   T ++  G  V    +++  AHE+GHN+G+ HD   T+C P  ++       G Y+MY  +  G + NN  FS CS R+I   +  +   CF+      CGN  V+  EECD G ++   D CC          C  KPG  CSP+   CCT  C FK     C  +D  + C    IC+G    C  P S   PN T+  R    C +G+C    CE+ ++E C C   +     E C +CC    +     +    + ++      +TL  G PC
Sbjct:   62 LDFHAHGRQFNLRMKRDTSLFSDEFKVETSNKV-----LDYDTSHIYTGHIYGEEGSFSHGSVIDGRFEGF-IKTRGGTFYIEPAERYIKDRILPFHSVIYHEDDINYPHKYGPQGGCADHSVFERMRKYQMTGVEEGARAHPEKHAASSGPELLRKKRTTLAERNTCQLYIQTDHLFFKYYGTREAVIAQ--ISSHVKAIDTIYQTTDFSGIRN-----ISFMVKRIRINTT-----SDEKDPTNPFRFPNIGVEKFLELNSEQNHDDYCLAYVFTDRDFDDGVLGLAWVGAP-SGSSGGIC-EKSKLYSDGKKKSLNTGIITVQN-YGSHVPPKVSHITFAHEVGHNFGSPHD-SGTECTPGESKNLGQKENGNYIMYARATSGDKLNNNKFSLCSIRNISQVLEKKRNNCFVESGQPICGNGMVEQGEECDCGYSDQCKDDCCFDANQPEGKKCKLKPGKQCSPSQGPCCTAQCAFKSKSEKC--RDDSD-CAKEGICNGFTALC--PASDPKPNFTDCNRHTQVCINGQCAGSICEKYDLEECTCASSDGKDDKELCHVCCMKKMAPSTCASTGSLQWSKQFSGRTITLQPGSPC 633          

Query:  179 ISFSTKFRKFKLILKPSVDLLSNDLKSVNIDRFGRETPVPIDGSQFYQGFVSGAEKSSVSAFLGNDKMLSINIILDDDIFQVEPLSRYVQNNS---SFIVYRYSDLKGNFTRGPKCFAKNISSFETN--------TTNSRQKRNVDAIISLPYINKDSTKKL-----CTIKLIADYRFHREHGRGEMGRTQHYLIELIDKINILFKSTDFVDSKNNKNSGYGFIINQILVHVE------------PTIGPSGHYNQEVAKQTDAWTVEGLLDSFGDIDHKDSCLAHLFTFQSFSEGTLGLAYMASSKTLSYGGICSERDFRHQNSKLVSVNTAWSTYRDAVGKRVISMSAYLVTAHELGHNWGADHDPDTTDCAPNAARG------GKYVMYTYSVVGYEPNNRLFSPCSRRSIGATIATRGEYCFLSPMNAFCGNSRVDDNEECDVGKNNS-ADACC-------TSDCHFKPGAVCS 1486
            + F    R+F L +K    L S++ K    ++      +  D S  Y G + G E S     + + +     I      F +EP  RY+++       ++Y   D+      GP+    + S FE             +R      A  S P + +     L     C + +  D+ F + +G  E    Q  +   +  I+ ++++TDF   +N       F++ +I ++              P IG                 VE  L+   + +H D CLA++FT + F +G LGLA++ +  + S GGIC E+   + + K  S+NT   T ++  G  V    +++  AHE+GHN+G+ HD   T+C P  ++       G Y+MY  +  G + NN  FS CS R+I   +  +   CF+      CGN  V+  EECD G ++   D CC          C  KPG  CS
Sbjct:   62 LDFHAHGRQFNLRMKRDTSLFSDEFKVETSNKV-----LDYDTSHIYTGHIYGEEGSFSHGSVIDGRFEGF-IKTRGGTFYIEPAERYIKDRILPFHSVIYHEDDINYPHKYGPQGGCADHSVFERMRKYQMTGVEEGARAHPEKHAASSGPELLRKKRTTLAERNTCQLYIQTDHLFFKYYGTREAVIAQ--ISSHVKAIDTIYQTTDFSGIRN-----ISFMVKRIRINTTSDEKDPTNPFRFPNIG-----------------VEKFLELNSEQNHDDYCLAYVFTDRDFDDGVLGLAWVGAP-SGSSGGIC-EKSKLYSDGKKKSLNTGIITVQN-YGSHVPPKVSHITFAHEVGHNFGSPHD-SGTECTPGESKNLGQKENGNYIMYARATSGDKLNNNKFSLCSIRNISQVLEKKRNNCFVESGQPICGNGMVEQGEECDCGYSDQCKDDCCFDANQPEGKKCKLKPGKQCS 505          

Query:  173 KKISFSTKFRKFKLILKPSVDLLSNDLKSVNIDRFGRETPVPIDGSQFYQGFVSGAEKSSVSAFLGNDKMLSINIILDDDIFQVEPLSRYV--QNNSSFIVYRYSDLK-------------GNFTRGPKCFAKNISSFETNTTNSRQKRNVDAIISLPYINKDSTKKLCTIKLIADYRFHREHGRGEMGRTQHYLIELIDKINILFKSTDFVDSKNNKN-SGYGFIINQILVHVEPTI--GPSGHYNQEVAKQTDAWTVEGLLDSFG-DIDHKDSCLAHLFTFQSFSEGTLGLAYMASSKTLSYGGICSERDFRHQNSKLVSVNTAWSTYRDAVGKRVISMSAYLVTAHELGHNWGADHDPDTTDCAPNAARGGKYVMYTYSVVGYEPNNRLFSPCSRRSIGATIATRGEYCFLSPMNAFCGNSRVDDNEECDVG--KNNSADACCTSDCHFK--PGAVCSPNNHECCTNDCQFKPYGFVCAAKDPMNPCVNHSICSGKEKEC-LGPLSIDGPNCTEHGRCSSGKCRPYCEQLNMEACICDKIEESCLICCRDPPSKINSNTIQECRPAQNGIQSRLTLNQGRPCALGVCEEGVCKRRVNKLVERIWKIIDEFNTNLFAAFLLENXXXXXXXXXXXXXXPAAILVSCNDAKHRRRFLQ 2074
            K++ F+T  + F+LIL P  D+L +  ++  +D  G ET V +D   FY G V G  +SSV A +  D  ++++I L ++ + +EP  R++      + + Y+ SD+K             G    G +   K       N  ++R+KR  D     P      TK  C + L+ADYRF +E G G    T +YLI LID+++ ++  T + D  + +   G GF+I +I+VH EPT   G   HYN    K    W V  LL+ F  +  HKD CLAHLFT   F  G LGLAY+ S +  S GGIC+   F+  N   + +N+  S+ R+  G+RVI+  A LVTAHE GHNWG++HDPD  +C+P+A++GG ++MYTYSV GY+ NN+ FSPCS RSI   +  +   CF  P  +FCGN RV+ +E+CD G       D+CC  +C  +   GA+CS  N  CC N CQF   G  C        C   + C+G   EC   P   DG  C E G+C +GKC PYCE   +++C+CD I ++C  CCR     IN    + C P    ++    L  G PC  G C +GVC++ +  +VER W II+E N      FL +N+V  V+++T + WIP + ++S  D K  R  ++
Sbjct:   64 KEVEFTTLGKNFRLILHPHRDVLHSKFRAYAVDADGNETVVHMDHDSFYSGRVFGELESSVRAHI-EDGTMTMSIHLPEETYHIEPSWRHLPEAKKDTMVAYKASDVKVHKNEAGATPKTCGYIKEGLELEDKEHGDTLDNELHTREKRQSDQYEYTP------TKTRCPLLLVADYRFFQEMGGGNTKTTINYLISLIDRVHKIYNDTVWQDRSDQEGFKGMGFVIKKIVVHSEPTRLRGGEAHYNMIREK----WDVRNLLEVFSREYSHKDFCLAHLFTDLKFEGGILGLAYVGSPRRNSVGGICTPEYFK--NGYTLYLNSGLSSSRNHYGQRVITREADLVTAHEFGHNWGSEHDPDIPECSPSASQGGSFLMYTYSVSGYDVNNKKFSPCSLRSIRKVLQAKSGRCFSEPEESFCGNLRVEGDEQCDAGLLGTEDNDSCCDKNCKLRRNQGAMCSDKNSPCCQN-CQFMASGMKCREAQ-YATCEQEARCTGAHAECPKSPAMADGTTCQERGQCRNGKCVPYCETQGLQSCMCDIIADACKRCCR---MSIN----ETCFP----VEPPDVLPDGTPCITGFCNKGVCEKTIQDVVERFWDIIEEINVAKTLRFLKDNIVMAVVLVTAVFWIPISCVISYFDRKKLRHEMK 695          

Query:  110 LSDYDILPNLNIR--------ISRSTFDNKKISFSTKFRKFKLILKPSVDLLSNDLKSVNIDRFGRETPVPIDGSQFYQGFVSGAEKSSVSAFLGNDKMLSINIILDDDIFQVEPLSRYVQN--NSSFIVYRYSDLKGNFTR--GPK-CFAKNISSFETNTTNSRQKRNVDAIISLP--YINKDSTKKLCTIKLIADYRFHREHGRGEMGRTQHYLIELIDKINILFKSTDFVDSKNNKNSGYGFIINQILVHVEPTIGPSG--HYNQEVA---KQTDAWTVEGLLDSFG-DIDHKDS--CLAHLFTFQSFSEGTLGLAYMASSKTLSYGGICSERDFRHQNSKLVSVNTAWSTYRDAVGKRVISMSAYLVTAHELGHNWGADHDPD-TTDCAPNAARGGKYVMYTYSVVGYEPNNRLFSPCSRRSIGATIATRGEYCFLSPMNAFCGNSRVDDNEECDVG---KNNSADACCTSDCHFKPGAVCSPNNHECCTNDCQFKPYGFVCAAKDPMNP-CVNHSICSGKEKECLGPLSI-DGPNCTEHGRCSSGKCRPYCE-QLNMEACICDKIEESCLICCRDPPSKINSNTIQECRPAQNGIQSRLTLNQGRPCALGVCE-EGVCKRRVNKLVERIWKIIDEFNTNLFAAFLLENXXXXXXXXXXXXXXPAAILVSCNDAKHRRRF 2068
            LSDYDIL   NI+        +  ST     ++FS   R FKL L  S +  S + K V +D    E+   +    F+ G V G   S V A + +D ++ I I  D   + +EPL R+V +  +   +VY+  D+K N +R   PK C    + + E        +   + ++       + D  K  C + ++AD+RF+R  GRGE   T +YLIELID+++ ++++T +    N    GYG  I QI +   P     G  HYN   +   ++ DAW V+ LL+ F  DI  + S  CLAHLFT+Q F  GTLGLAY+ S +  S+GG+C +  +     K + +N+  ++ ++  GK +++  A LVT HELGHN+GA+HDPD   +CAPN  +GGKYVMY  +V G   NN++FS CS++SI  TI ++ + CF    N  CGNSRVD+ EECD G    NN  D CC SDC  K G  CS  N  CC N CQF+     C  ++ +N  C   S C+G   EC  P +  D   C + G+C  GKC P+CE +  +E+C C++ + SC +CCRD   +        C P  +  Q  L L +G+PC +G C+  G C++RV  ++ER W  ID+ + N F  FL +N+VG+V++ +LI WIP +ILV C D K  +++
Sbjct:   39 LSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDG-KNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVI-IRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIK-NVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSW---DNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKN-YGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNN--DTCCNSDCTLKEGVQCSDRNSPCCKN-CQFETAQKKC--QEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGR--------CVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQY 702          

Query:  110 LSDYDILPNLNIR--------ISRSTFDNKKISFSTKFRKFKLILKPSVDLLSNDLKSVNIDRFGRETPVPIDGSQFYQGFVSGAEKSSVSAFLGNDKMLSINIILDDDIFQVEPLSRYVQN--NSSFIVYRYSDLKGNFTR--GPK-CFAKNISSFETNTTNSRQKRNVDAIISLPYINK-------DSTKKLCTIKLIADYRFHREHGRGEMGRTQHYLIELIDKINILFKSTDFVDSKNNKNSGYGFIINQILVHVEPTIGPSGHYNQEVAK-----QTDAWTVEGLLDSFG-DIDHKDS--CLAHLFTFQSFSEGTLGLAYMASSKTLSYGGICSERDFRHQNSKLVSVNTAWSTYRDAVGKRVISMSAYLVTAHELGHNWGADHDPD-TTDCAPNAARGGKYVMYTYSVVGYEPNNRLFSPCSRRSIGATIATRGEYCFLSPMNAFCGNSRVDDNEECDVG---KNNSADACCTSDCHFKPGAVCSPNNHECCTNDCQFKPYGFVCAAKDPMNP-CVNHSICSGKEKECLGPLSI-DGPNCTEHGRCSSGKCRPYCE-QLNMEACICDKIEESCLICCRDPPSKINSNTIQECRPAQNGIQSRLTLNQGRPCALGVCE-EGVCKRRVNKLVERIWKIIDEFNTNLFAAFLLENXXXXXXXXXXXXXXPAAILVSCNDAKHRRRF 2068
            LSDYDIL   NI+        +  +T     ++FS   R FKL L  S +  S +L+ V +D    E+   +    F+ G V G   S V A +G+D  +++ I  D   + VEPL R+V +  +   +VY+  D+K +F+R   PK C   N  S E        K  +D   S  ++ +       +  K  C + ++AD+RF++  GRGE   T +YLIELID+++ ++++T +    N    GYG  I QI +   P     G  +  +AK     + DAW V+ LL+ F  DI  + S  CLAHLFT+Q F  GTLGLAY+ S +  S+GG+C +  +     K + +N+  ++ ++  GK +++  A LVT HELGHN+GA+HDPD   +CAPN  +GGKYVMY  +V G   NN++FS CS++SI  TI ++ + CF    N  CGNSRVD+ EECD G    NN  D CC SDC  KPG  CS  N  CC N CQF+     C  ++ +N  C   S C+G   EC  P    D   C + G+C +GKC P+C+ +  +E+C C   + SC +CCR        N    C P  +  Q  L L +G+PC +G C+  G C++RV  ++ER W  ID+ + N F  FL +N+VG+V++ +LI WIP +ILV C D K  +++
Sbjct:   39 LSDYDILSLANIQQHSIRKRDLQSATHLETLLTFSALKRHFKLYLTSSTERFSQNLRVVVVDG-KEESEYSVKWQNFFSGHVVGEPDSRVLAHIGDDD-VTVRINTDGAEYNVEPLWRFVNDTKDKRMLVYKSEDIK-DFSRLQSPKVCGYLNADSEEL-----LPKGLIDREPSEEFVRRVKRRAEPNPLKNTCKLLVVADHRFYKYMGRGEESTTTNYLIELIDRVDDIYRNTSW---DNAGFKGYGVQIEQIRILKSPQEVKPGERHFNMAKSFPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYNPTVKKNIYLNSGLTSTKN-YGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNN--DTCCNSDCTLKPGVQCSDRNSPCCKN-CQFETAQKKC--QEAINATCKGVSYCTGNSSECPPPGDAEDDTVCLDLGKCKAGKCIPFCKREQELESCACVDTDNSCKVCCR--------NLSGPCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQY 702          

Query:  110 LSDYDILPNLNIR--------ISRSTFDNKKISFSTKFRKFKLILKPSVDLLSNDLKSVNIDRFGRETPVPIDGSQFYQGFVSGAEKSSVSAFLGNDKMLSINIILDDDIFQVEPLSRYVQN--NSSFIVYRYSDLKGNFTR--GPK-CFAKNISSFETNTTNSRQKRNVDAIISLPYINK-------DSTKKLCTIKLIADYRFHREHGRGEMGRTQHYLIELIDKINILFKSTDFVDSKNNKNSGYGFIINQILVHVEPTIGPSGHYNQEVAK-----QTDAWTVEGLLDSFG-DIDHKDS--CLAHLFTFQSFSEGTLGLAYMASSKTLSYGGICSERDFRHQNSKLVSVNTAWSTYRDAVGKRVISMSAYLVTAHELGHNWGADHDPD-TTDCAPNAARGGKYVMYTYSVVGYEPNNRLFSPCSRRSIGATIATRGEYCFLSPMNAFCGNSRVDDNEECDVG---KNNSADACCTSDCHFKPGAVCSPNNHECCTNDCQFKPYGFVCAAKDPMNP-CVNHSICSGKEKECLGPLSI-DGPNCTEHGRCSSGKCRPYCE-QLNMEACICDKIEESCLICCRDPPSKINSNTIQECRPAQNGIQSRLTLNQGRPCALGVCE-EGVCKRRVNKLVERIWKIIDEFNTNLFAAFLLENXXXXXXXXXXXXXXPAAILVSCNDAKHRRRF 2068
            LSDYDIL   NI+        +  +T     ++FS   R FKL L  S +  S +L+ V +D    E+   +    F+ G V G   S V A +G+D  +++ I  D   + +EPL R+V +  +   +VY+  D+K +F+R   PK C   N  S E        K  +D   S  ++ +       +  K  C + ++AD+RF++  GRGE   T +YLIELID+++ ++++T +    N    GYG  I QI +   P     G  +  +AK     + DAW V+ LL+ F  DI  + S  CLAHLFT+Q F  GTLGLAY+ S +  S+GG+C +  +     K + +N+  ++ ++  GK +++  A LVT HELGHN+GA+HDPD   +CAPN  +GGKYVMY  +V G   NN++FS CS++SI  TI ++ + CF    N  CGNSRVD+ EECD G    NN  D CC SDC  KPG  CS  N  CC N CQF+     C  ++ +N  C   S C+G   EC  P    D   C + G+C +GKC P+C+ +  +E+C C   + SC +CCR        N    C P  +  Q  L L +G+PC +G C+  G C++RV  ++ER W  ID+ + N F  FL +N+VG+V++ +LI WIP +ILV C D K  +++
Sbjct:   39 LSDYDILSLSNIQQHSIRKRDLQSATHLETLLTFSALKRHFKLYLTSSTERFSQNLRVVVVDG-KEESEYSVKWQDFFSGHVVGEPDSRVLAHIGDDD-VTVRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIK-DFSRLQSPKVCGYLNADSEEL-----LPKGLIDREPSEEFVRRVKRRAEPNPLKNTCKLLVVADHRFYKYMGRGEESTTTNYLIELIDRVDDIYRNTSW---DNAGFKGYGVQIEQIRILKSPQEVKPGERHFNMAKSFPNEEKDAWDVKMLLEQFSLDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYNPGVKKNIYLNSGLTSTKN-YGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNN--DTCCNSDCTLKPGVQCSDRNSPCCKN-CQFETAQKKC--QEAINATCKGVSYCTGNSSECPPPGDAEDDTVCLDLGKCKAGKCIPFCKREQELESCACADTDNSCKVCCR--------NLSGPCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQY 702          

Query:  632 CTIKLIADYRFHREHGRGEMGRTQHYLIELIDKINILFKSTDFVDSKNNKNSG------YGFIINQILVHVEPTIGPSGHYNQEVAKQTDAWTVEGLLDSFGDID-HKDSCLAHLFTFQSFSE-GTLGLAYMASSK-TLSYGGICSERDFRHQNSKLVSVNTAWSTY---RDAVGKRVISMSAYLVTAHELGHNWGADHDP-------DTTDCAPNAARGGKYVMYTYSVVGYEPNNRLFSPCSRRSIGATIATRGEYCFLSPMNAFCGNSRVDDNEECDVGKNNSADA-CCTSDCHFKPGAVCSPNNHECCTNDCQFKPYGFVCAAKDPMNPCVNHSICSGKEKEC-LGPLSIDGPNCTEHGRCSSGKCRPYCEQLNM--EACICDKIEESCLICCRDPPSKINSNTIQECRPAQNGIQSRLTLNQGRPCALGVCEEGVCKRRVNKLVERI 1918
            CT+KL+ADY F+   G+   G    +L+ +I ++N ++   ++   K +  SG       GF I +I V   P    S HYN      +  W VE LL  F   +  KD CL HL T ++F E  TLGLAY++  K   + GGICS+++    N ++  +N   ST     +     +I+    +V +HE GH WGA HDP       D  +C+PN   GGKY+M  Y+  GY+ NN LFSPCSR+ I   +  + E CF   M +FCGN  V+D EECD G +   +  CC   C    GA CSP NH CCT  CQF     VC   D +  C   ++C+G   EC   P   DG  C E G C +G C P+CE++++  ++CIC+ +E SC +CCRD            C P    +   + L  G  C+ G C +  C   VN++V+ +
Sbjct:  189 CTLKLVADYSFYSIFGKNNTGIVTKFLVNMIARVNEIYTPINWDVGKEDDISGRGRFQNMGFSIKEIKVLDRPNASDS-HYNS----YSRIWEVERLLREFAFAEGSKDFCLVHLVTARTFREVATLGLAYVSYKKWDETAGGICSKQE--TFNGRVAYINVLLSTSFANSEQSTYPLITKEIDIVVSHEYGHAWGATHDPTIDSDDPDVEECSPNDQNGGKYLMSQYAQKGYDANNVLFSPCSRKLIRDVLIGKWESCFQEEMTSFCGNGIVEDGEECDNGVDTDNEFNCCDKFCRLAVGAKCSPLNHICCTPTCQFHNSTHVCLPGDSL-LCKADAVCNGFSGECPSAPPVRDGQECLEGGECLNGVCLPFCEKMSIGKKSCICEDLELSCRLCCRDYNGT--------CAP----VPGHVYLRDGVRCSKGSCRDRKC---VNEVVDNV 617          

Query:  170 NKKISFSTKFRKFKLILKPSVDLLSNDLKSVNIDRFGRETPVPIDGSQFYQGFVSGAEKSSVSAFLGNDKMLSINIILDDDIFQVEPLSRYVQ----------------NNSSFIVYRYSDLKGNFTRG-----PKCFAKNISSFETNTTNSRQ---KRNV-------DAIISLPYINKDSTKKLCTIKLIADYRFHREHGRGEMGRTQHYLIELIDKINILFKSTDFVDSKNNKN-SGYGFIINQILVHVEPTIGPSGHYNQEVAKQTDAWTVEGLLDSFGDID-HKDSCLAHLFTFQSFSEGTLGLAYMASSKTLSYGGICSERDFRHQNSKLVSVNTAWSTYRDAVGKRVISMSAYLVTAHELGHNWGADHDPDTTDCAPNAARGGKYVMYTYSVVGYEPNNRLFSPCSRRSIGATIATRGEYCFLSPMNAFCGNSRVDDNEECDVG---KNNSADACCTSDCHFKPGAVCSPNNHECCTNDCQFKPYGFVCAAKDPMNPCVNHSICSGKEKECLGPLSI---DGPNCTEHGRCSSGKCRPYCEQLNMEACICDKIEESCLICCRDPPSKINSNTIQECRPAQNGIQSRLTLNQGRPCALGVCEEGVCKRRVNKLVERIWKIIDEFNTNLFAAFLLENXXXXXXXXXXXXXXPAAILVSCNDAKHRRRFLQERKSRRP 2095
            +K+ISF    R F+LIL P+  LLS   K+  +DR G   PV +D SQF++G + G  +S+VSA L +D +L+ +I L  D++ VEP  R+ +                NN+S IVYR SD+  ++ R      P  F   I  +E  T N  +   KR +       D ++  P  + + T+  C++ L+AD++F+   G      T +++I LID++N +F  T++ D++  +   G GF+I ++LVH EPT   +G  +  +A +   W V  LL+ F   + H+  CLAHLFT Q F  G LGLAY+ S +  S GGICS    +  N   + +N+  ST R+  G RVI+  A LVTAHE GHNWG++HDPD  +C+P++ +GG Y+MYTYSV GY+ NN+ FSPCS RSI A +  +   CF  P  +FCGN  V++ EECD G    + ++D CCT+ C  K GA CS  N  CC  DCQ+   G +C    P N C   + CSG+  EC  P S    D   C + G+C +G C PYCE L   +C+CD   ++C  CCR       ++T Q   P +        L+ G PC  G CEEG CK+ V  +VER W II++ + N    FL +N+V  V+IL  +LWIP + L+   D K  R   +  KSR P
Sbjct:   71 SKEISFRALGRSFQLILSPTKGLLSAQFKAYTVDRTGARRPVWVDNSQFFEGKLLGEVESNVSAHL-DDGLLTASIRLPQDVYIVEPSWRHAEALQHPDFREGSHENLSNNTSMIVYRASDVIYSWERAESHADPSRFCGAI--YENGTANVGRMFGKRELVQEGPEGDPVVGEPLRSYEPTQTRCSLLLVADHKFYENMGGKSQKGTINFIISLIDRVNKIFLDTEWKDNERQQGFRGMGFVIQEVLVHTEPTPVVNGQEHYNMAGKN--WNVRELLEVFSRSENHRWFCLAHLFTDQKFEGGILGLAYVGSPRKNSVGGICSPGYVK--NGHTLYLNSGLSTSRNHYGHRVITREADLVTAHEFGHNWGSEHDPDLPECSPDSQKGGSYLMYTYSVSGYDVNNKRFSPCSVRSIRAVLLAKAGKCFSKPEESFCGNLLVEEGEECDAGLSASSETSDPCCTAQCKLKSGAKCSDRNSPCC-KDCQYMEVGILCREAMP-NACKKEAFCSGESAEC--PPSKPQDDDSACLDRGKCRTGDCLPYCETLGQTSCMCDNEADACKRCCR----PHQNSTCQPVEPVE-------VLHDGTPCIHGFCEEGSCKKTVQDIVERFWDIIEDIDINTVLKFLHDNIVSFVLILVTVLWIPVSCLIGYTDKKRFREMQEWAKSREP 729          

Query:  173 KKISFSTKFRKFKLILKPSVDLLSNDLKSVNIDRFGRETPVPIDGSQFYQGFVSGAEKSSVSAFLGNDKMLSINIILDDDIFQVEPLSRYV--QNNSSFIVYRYSDLK---------GNFTRGPKC-FAKNISSFETN-TTNSRQKRNVDAIISLPYINKDSTKKLCTIKLIADYRFHREHGRGEMGRTQHYLIELIDKINILFKSTDFVDSKN-NKNSGYGFIINQILVHVEP--TIGPSGHYNQEVAKQTDAWTVEGLLDSFG-DIDHKDSCLAHLFTFQSFSEGTLGLAYMASSKTLSYGGICSERDFRHQNSKLVSVNTAWSTYRDAVGKRVISMSAYLVTAHELGHNWGADHDPDTTDCAPNAARGGKYVMYTYSVVGYEPNNRLFSPCSRRSIGATIATRGEYCFLSPMNAFCGNSRVDDNEECDVG--KNNSADACCTSDCHFKPGAVCSPNNHECCTNDCQFKPYGFVCAAKDPMNPCVNHSICSGKEKEC-LGPLSIDGPNCTEHGRCSSGKCRPYCEQLNMEACICDKIEESCLICCRDPPSKINSNTIQECRPAQNGIQSRLTLNQGRPCALGVCEEGVCKRRVNKLVERIWKIIDEFNTNLFAAFLLENXXXXXXXXXXXXXXPAAILVSCNDAKHRRRFLQERKSRRPEVFENFS 2116
            ++I  +T  R F+LIL P   +L +  K+ +++  G+ET VPID   F +G V G   S V+  +  D +++ NI + DDI+ +EP  R++   +N + I Y+ SD+K          ++     C + K  S  E N T +  +KR +D      Y     TK  C + L+ADYRF +E G      T +YLI LID+++ ++  T + D +  +   G GF+I +I+VH EP  T     HYN       D W V  LL+ F  +  HKD CLAHLFT   F  G LGLAY+ S +  S GGIC+   F+  N   + +N+  S+ R+  G+RVI+  A LVTAHE GHNWG++HDPD  +C+P+A++GG Y+MYTYSV GY+ NN+ FSPCS RSI   +  + E CF  P  +FCGN RV+ +EECD G       DACC  DC  +  A+CS  N  CC N CQ+   G  C        C   S C+G   EC   P   DG +C E G+C  GKC P+CE   M++C+CD IE +C  CCR   S IN    + C P    + S   L  G PC  G C  G C++ V  +VER W II++ N N    FL +N+VGTV+++T +LWIPA+ ++S  D K R+  L+  + R+    E F+
Sbjct:   57 REIRLNTHGRDFRLILSPKRSILHSKFKAYSVNGDGQETHVPIDHGSFMEGRVFGETDSHVNMHV-EDGVMTGNIHMPDDIYHIEPSWRHIPGHDNRTMITYKQSDIKFSWDAENLPADYPTPRTCAYIKEGSEMEENETAHHIEKRQLDQ-----YDQYRFTKTRCPLLLVADYRFFQEMGASNTKTTINYLISLIDRVHKIYNDTIWQDRQEVDGFKGMGFVIKKIVVHSEPSKTKSQEAHYNM----IRDKWDVRNLLEVFSREFTHKDFCLAHLFTDLKFEGGILGLAYVGSPRRNSVGGICTPEYFK--NGYTLYLNSGLSSSRNHYGQRVITREADLVTAHEFGHNWGSEHDPDIPECSPSASQGGSYLMYTYSVSGYDVNNKRFSPCSLRSIRKVLQAKSEKCFSEPEESFCGNLRVEGDEECDAGLLGTEDNDACCDKDCKLRIKAMCSDKNSPCCQN-CQYMRSGVKCREAQ-YATCEKESTCTGHSSECPKSPPMSDGTDCQERGKCKGGKCIPFCETQGMQSCMCDIIENACKRCCR---SSIN----ETCSP----VDSADILADGTPCIQGFCNSGNCEKTVQDVVERFWDIIEDININKVMLFLRDNIVGTVVLITAVLWIPASCIISFVDKKRRKEELKRAEWRKCLTKEMFN 699          

Query:  173 KKISFSTKFRKFKLILKPSVDLLSNDLKSVNIDRFGRETPVPIDGSQFYQGFVSGAEKSSVSAFLGNDKMLSINIILDDDIFQVEPLSRYVQ--NNSSFIVYRYSDLKGNFTR--------GPKC--FAKNISSFETNTTNS----------RQKRNVDAIISLPYINKDSTKKLCTIKLIADYRFHREHGRGEMGRTQHYLIELIDKINILFKSTDFVDSKN-NKNSGYGFIINQILVHVEPTI--GPSGHYNQEVAKQTDAWTVEGLLDSFG-DIDHKDSCLAHLFTFQSFSEGTLGLAYMASSKTLSYGGICSERDFRHQNSKLVSVNTAWSTYRDAVGKRVISMSAYLVTAHELGHNWGADHDPDTTDCAPNAARGGKYVMYTYSVVGYEPNNRLFSPCSRRSIGATIATRGEYCFLSPMNAFCGNSRVDDNEECDVG--KNNSADACCTSDCHFK--PGAVCSPNNHECCTNDCQFKPYGFVCAAKDPMNPCVNHSICSGKEKEC-LGPLSIDGPNCTEHGRCSSGKCRPYCEQLNMEACICDKIEESCLICCRDPPSKINSNTIQECRPAQNGIQSRLTLNQGRPCALGVCEEGVCKRRVNKLVERIWKIIDEFNTNLFAAFLLENXXXXXXXXXXXXXXPAAILVSCNDAKHRRRFLQERKSR 2089
            K+++F    + F++IL P  D+L +  K+ ++D  G++T V  D + FY+G V G  KS  +  + ND +++  + L D+ + +EP  R++   NN + IVY+ SD+K ++ +        GPK   + K  S  E++  N           R+KR VD     P      TK  C + L+ADYRF +E G      T +YLI LID+++ ++  T + D +  +   G GF+I +I+VH EPT   G   HYN    K    W V  LL+ F  +  HKD CLAHLFT   F  G LGLAY+ S +  S GGIC+   F+  N   + +N+  S+ R+  G+RVI+  A LVTAHE GHNWG++HDPD  +C+P+A++GG Y+MYTYSV GY+ NN+ FSPCS RSI   +  + E CF  P  +FCGN RV+ +EECD G       D CC  DC  +   GAVCS  N  CC N CQ+   G  C  K     C   S C+G   EC   P   DG +C E G+C  GKC PYCE   +++C+CD IE +C  CCR       ++  + C P    I+    L  G PC  G C +G C++ +  +VER W II++ N N    FL +N+VG+V+I+T ++WIPA+ LV   D K R++  +ER  R
Sbjct:   56 KEVAFKALGKDFRIILTPKRDVLHSKFKAYSVDGDGKQTSVHFDHNNFYRGRVFGEMKSDANLHIDNDGVMTGALHLPDETYHIEPSWRHLSDGNNKTMIVYKGSDVKLSWDQSNYNDDVMGPKICGYIKEGSELESDAENEVENVWKSNTHREKRQVDHYEYTP------TKTRCPLLLVADYRFFQEMGASNTKTTINYLISLIDRVHKIYNDTIWHDRQELDGFKGMGFVIKKIVVHSEPTRVRGGEAHYNMVREK----WDVRNLLEVFSREYSHKDFCLAHLFTDLKFEGGILGLAYVGSPRRNSVGGICTPEYFK--NGYTLYLNSGLSSSRNHYGQRVITREADLVTAHEFGHNWGSEHDPDIPECSPSASQGGSYLMYTYSVSGYDVNNKRFSPCSLRSIRKVLQAKSERCFSQPEESFCGNLRVEGDEECDAGLLGTEDNDPCCDKDCKLRRIQGAVCSDKNSPCCQN-CQYMTKGVEC-RKAQYTTCERESNCTGMHAECPRSPPMPDGTDCQERGKCRGGKCTPYCETQGLQSCMCDIIENACRRCCR-------TSMNETCFP----IEPPDILPDGTPCIQGFCNKGSCEKTIQDVVERFWDIIEDININKVLLFLRDNIVGSVVIITALIWIPASCLVGYVDRKRRKQ--EERYWR 698          

Query:  173 KKISFSTKFRKFKLILKPSVDLLSNDLKSVNIDRFGRETPVPIDGSQFYQGFVSGAEKSSVSAFLGNDKMLSINIILDDDIFQVEPLSRYVQ--NNSSFIVYRYSDLKGNFTR--------GPKC--FAKNISSFETNTTNS----------RQKRNVDAIISLPYINKDSTKKLCTIKLIADYRFHREHGRGEMGRTQHYLIELIDKINILFKSTDFVDSKN-NKNSGYGFIINQILVHVEPTI--GPSGHYNQEVAKQTDAWTVEGLLDSFG-DIDHKDSCLAHLFTFQSFSEG---TLGLAYMASSKTLSYGGICSERDFRHQNSKLVSVNTAWSTYRDAVGKRVISMSAYLVTAHELGHNWGADHDPDTTDCAPNAARGGKYVMYTYSVVGYEPNNRLFSPCSRRSIGATIATRGEYCFLSPMNAFCGNSRVDDNEECDVG--KNNSADACCTSDCHFK--PGAVCSPNNHECCTNDCQFKPYGFVCAAKDPMNPCVNHSICSGKEKEC-LGPLSIDGPNCTEHGRCSSGKCRPYCEQLNMEACICDKIEESCLICCRDPPSKINSNTIQECRPAQNGIQSRLTLNQGRPCALGVCEEGVCKRRVNKLVERIWKIIDEFNTNLFAAFLLENXXXXXXXXXXXXXXPAAILVSCNDAKHRRRFLQERKSR 2089
            K+++F    + F++IL P  D+L +  K+ ++D  G++T V  D + FY+G V G  KS  +  + ND +++  + L D+ + +EP  R++   NN + IVY+ SD+K ++ +        GPK   + K  S  E++  N           R+KR VD     P      TK  C + L+ADYRF +E G      T +YLI LID+++ ++  T + D +  +   G GF+I +I+VH EPT   G   HYN    K    W V  LL+ F  + +++D CLAHLFT Q+FS      LGLAY+AS +   +GGIC++  F+  N   + +N+  S+ R+  G+RVI+  A LVTAHE GHNWG++HDPD  +C+P+A++GG Y+MYTYSV GY+ NN+ FSPCS RSI   +  + E CF  P  +FCGN RV+ +EECD G       D CC  DC  +   GAVCS  N  CC N CQ+   G  C  K     C   S C+G   EC   P   DG +C E G+C  GKC PYCE   +++C+CD IE +C  CCR       ++  + C P    I+    L  G PC  G C +G C++ +  +VER W II++ N N    FL +N+VG+V+I+T ++WIPA+ LV   D K R++  +ER  R
Sbjct:   56 KEVAFKALGKDFRIILTPKRDVLHSKFKAYSVDGDGKQTSVHFDHNNFYRGRVFGEMKSDANLHIDNDGVMTGALHLPDETYHIEPSWRHLSDGNNKTMIVYKGSDVKLSWDQSNYNDDVMGPKICGYIKEGSELESDAENEVENVWKSNTHREKRQVDHYEYTP------TKTRCPLLLVADYRFFQEMGASNTKTTINYLISLIDRVHKIYNDTIWHDRQELDGFKGMGFVIKKIVVHSEPTRVRGGEAHYNMVREK----WDVRNLLEVFSRNKEYEDFCLAHLFTHQTFSARDSVVLGLAYIASPQDRRHGGICTKEYFK--NGYTLYLNSGLSSSRNHYGQRVITREADLVTAHEFGHNWGSEHDPDIPECSPSASQGGSYLMYTYSVSGYDVNNKRFSPCSLRSIRKVLQAKSERCFSQPEESFCGNLRVEGDEECDAGLLGTEDNDPCCDKDCKLRRIQGAVCSDKNSPCCQN-CQYMTKGVEC-RKAQYTTCERESNCTGMHAECPRSPPMPDGTDCQERGKCRGGKCTPYCETQGLQSCMCDIIENACRRCCR-------TSMNETCFP----IEPPDILPDGTPCIQGFCNKGSCEKTIQDVVERFWDIIEDININKVLLFLRDNIVGSVVIITALIWIPASCLVGYVDRKRRKQ--EERYWR 701          

Query:  173 KKISFSTKFRKFKLILKPSVDLLSNDLKSVNIDRFGRETPVPIDGSQFYQGFVSGAEKSSVSAFLGNDKMLSINIILDDDIFQVEPLSRYV--QNNSSFIVYRYSDLKGNFTRG------PKCFAKNISSFET-----NTTNS--RQKRNVDAIISLPYINKDSTKKLCTIKLIADYRFHREHGRGEMGRTQHYLIELIDKINILFKSTDFVDSKNNKN-SGYGFIINQILVHVEPTIGPSG--HYNQEVAKQTDAWTVEGLLDSFG-DIDHKDSCLAHLFTFQSFSEGTLGLAYMASSKTLSYGGICSERDFRHQNSKLVSVNTAWSTYRDAVGKRVISMSAYLVTAHELGHNWGADHDPDTTDCAPNAARGGKYVMYTYSVVGYEPNNRLFSPCSRRSIGATIATRGEYCFLSPMNAFCGNSRVDDNEECDVG--KNNSADACCTSDCHFK--PGAVCSPNNHECCTNDCQFKPYGFVCAAKDPMNPCVNHSICSGKEKEC-LGPLSIDGPNCTEHGRCSSGKCRPYCEQLNMEACICDKIEESCLICCRDPPSKINSNTIQECRPAQNGIQSRLTLNQGRPCALGVCEEGVCKRRVNKLVERIWKIIDEFNTNLFAAFLLENXXXXXXXXXXXXXXPAAILVSCNDAKHRRRFLQERKSRRPEVFENFS*EA----ILFCWSPV-KSHRINSETV 2179
            K++SF+T  R F+LIL P   LL +  ++ +ID  G ETP+ +D   FY G V G + S  S  L    M +I I +  + + +EP  R++  ++N + + Y+ SD++ ++         P  + K  +  ET     + +NS  R KR+VD   S  Y+    T+  C + L+ADYRF RE G G+   T +YLI LID+++ ++  T +++ + +    G GF+I +I VH +PT   S   HYN    K    W V  LL+ F  +  HKD CLAHLFT   F  G LGLAY+ S +  S GGIC+   F+  N   + +N+  S+ R+  G+RVI+  A LVTAHE GHNWG++HDPD T+C+P A++GG ++MYTYSV GY+ NN+ FSPCS RSI   +  +   CF  P  +FCGN RV+ NEECD G       D+CC  +C  +   GA CS  N  CC N CQF   G  C  +     C   S C+G   EC   P   DG  C E G+C SGKC PYCE   +++C+CD I +SC  CCR       +N    C P    +     L  G PC  G C +GVC++ +  +VER W II+E N N    FL +N+VGTVI++T ++W+PA+ +++  D K  +   + RK    + F   S +A    +++   P+ ++  IN E +
Sbjct:   56 KEVSFTTLGRDFRLILTPKKGLLHHQFEATSIDAEGNETPIAVDHDHFYDGRVFGEKSSHASVHLDEGVMTAI-IDVPGETYHIEPSWRHMSDKDNKTMVSYKASDVRLSWEHSDLKQHKPCAYVKEDAEVETVDEDDDNSNSITRSKRDVD---SYDYMIT-PTRTRCPLLLVADYRFFREMGGGDTKTTINYLISLIDRVHKIYNDTLWLERQESDGFRGMGFVIKKITVHSDPTKVRSSEDHYNMVREK----WDVRSLLEVFSREYSHKDFCLAHLFTDLKFEGGILGLAYVGSPRRNSVGGICTPEYFK--NGYTLYLNSGLSSSRNHYGQRVITREADLVTAHEFGHNWGSEHDPDITECSPTASQGGSFLMYTYSVSGYDINNKRFSPCSLRSIRKVLQAKSARCFSEPEESFCGNLRVEGNEECDAGLLGTEDNDSCCDKNCKLRRAQGARCSDKNSPCCQN-CQFMASGVKC-REGQFATCEQESRCTGTGAECPKSPPMPDGTGCLERGKCRSGKCIPYCETQGLQSCMCDTILQSCKRCCR-------TNLNDTCYP----VDPPDVLPDGTPCIQGFCNKGVCEKTIQDVVERFWDIIEEININKMLRFLKDNIVGTVILITGLIWVPASCIINWLDHKRAKEARERRKWEDQDDFVQMSNDARPKKVIYIKVPINRNGSINDEQM 729          

Query:  149 ISRSTFDNKKISFSTKFRKFKLILKPSVDLLSNDLKSVNIDRFGRETPVPIDGSQFYQGFVSGAEKSSVSAFLGNDKMLSINIILDDDIFQVEPLSRYVQ--NNSSFIVYRYSDLKGNFTR--GPK-CFAKNISSFETNTTNSRQKRNVDAIISLPYINK---------DSTKKLCTIKLIADYRFHREHGRGEMGRTQHYLIELIDKINILFKSTDFVDSKNNKNSGYGFIINQILVHVEPTIGPSG--HYNQEVAKQTDAWTVEGLLDSFG-DIDHKDS--CLAHLFTFQSFSEGTLGLAYMASSKTLSYGGICSER-DFRHQNSKLVSVNTAWSTYRDAVGKRVISMSAYLVTAHELGHNWGADHDPDTTD-CAPNAARGGKYVMYTYSVVGYEPNNRLFSPCSRRSIGATIATRGEYCFLSPMNAFCGNSRVDDNEECDVG-KNNSADACCTSDCHFKPGAVCSPNNHECCTNDCQFKPYGFVCAAKDPMNP-CVNHSICSGKEKECLGPLS-IDGPNCTEHGRCSSGKCRPYCEQ-LNMEACICDKIEESCLICCRDPPSKINSNTIQECRPAQNGIQSRLTLNQGRPCALGVCE-EGVCKRRVNKLVERIWKIIDEFNTNLFAAFLLENXXXXXXXXXXXXXXPAAILVSCNDAKHRRRF 2068
            +   T   + +SF+   + F+L L  + +L ++D  ++ I   G      +    F+ G V G E S V A + N+   + +I+ D+  + +EP+ R+++   +   +VYR  D++ N +R   PK C   N  + +      R    ++       + K         D +K  C + L+ADYRF R  GR E   T +YLIELID+++ ++++T +    + +  GYG  I QI+V+ +PT    G  H+N + +   D W V+ LL+ F  DI    S  CLAHLFT+Q F EGTLGLAY+A +K  + GG+CS+       + + + +NT  ++ ++  GK +++  A LVT HELGHN+GA HDPD    CAP+  +GGKYVMY  +V G   NN+LFS CS+ SI   +  +G  CF    +  CGNSRV++ EECD G  + S D CCT+DC  +PG +CS  N  CC N C ++  G  C  ++ +N  C   S C+G   +C  P + +D   C + G+C +G C P+CE  L +++C C++ + SC +CCR        N    C P Q+     L L +G+PC +G C+  G C ++V  ++ER+W  ID+ N N F  FL +N+VG+V+  +L+ WIP +ILV C D K  +++
Sbjct:   60 VETHTHAERLLSFTALQKHFRLYLATNTELFTDDFNTLVIGEDGTHEVYEVQRENFFTGHVIGEENSRVQAHINNND-FTAHILTDEAEYNIEPMWRFIEGPQDDRLLVYRSEDIR-NVSRLAAPKVCGYINAEATQLLPDGVRAGTALEEEEEEEEVEKHLREKRQVVDHSKNTCPLLLVADYRFFRNMGRREESTTINYLIELIDRVDDIYRNTSW----DEEFKGYGVQIQQIIVNKDPTPVEPGKAHFNMKGSPTKDVWDVKKLLEQFSIDIAANASKVCLAHLFTYQDFDEGTLGLAYVAPAKDGAPGGLCSKECPQSSSDRQAIYLNTGLTSTKN-YGKTILTKEADLVTTHELGHNFGAVHDPDDVPYCAPSEDQGGKYVMYPIAVSGDHSNNKLFSNCSKISIVKRLRHKGPSCFKERNSKVCGNSRVEEGEECDPGLLHLSTDPCCTADCKLRPGKLCSDRNSACCKN-CVYEKKGKQC--QEQINATCKGESYCTGTSSKCPPPENLLDKTTCVDSGQCMNGVCIPFCEAFLKLQSCACNETDNSCKVCCR--------NRAGACSPYQDDRGKFLYLRKGKPCTVGFCDGGGKCMKQVQDVIERLWDFIDKLNINTFGKFLADNIVGSVVAFSLVFWIPLSILVHCMDKKLDQQY 707          

Query:  110 LSDYDILPNLNIR--------ISRSTFDNKKISFSTKFRKFKLILKPSVDLLSNDLKSVNIDRFGRETPVPIDGSQFYQGFVSGAEKSSVSAFLGNDKMLSINIILDDDIFQVEPLSRYVQN--NSSFIVYRYSDLKGNFTR--GPKC--FAKNISS--FETNTTNSRQKRNVDAIISLPYINKDSTKKLCTIKLIADYRFHREHGRGEMGRTQHYLIELIDKINILFKSTDFVDSKNNKNSGYGFIINQILVHVEPTIGPSG--HYNQEVA-----KQTDAWTVEGLLDSFG-DIDHKDS--CLAHLFTFQSFSEGTLGLAYMASSKTLSYGGICSERDFRHQNSKLVS-VNTAWSTYRDAVGKRVISMSAYLVTAHELGHNWGADHDPDTTD-CAPNAARGGKYVMYTYSVVGYEPNNRLFSPCSRRSIGATIATRGEYCFLSPMNAFCGNSRVDDNEECDVG-KNNSADACCTSDCHFKPGAVCSPNNHECCTNDCQFKPYGFVCAAKDPMNP-CVNHSICSGKEKECLGPLSI-DGPNCTEHGRCSSGKCRPYCE-QLNMEACICDKIEESCLICCRDPPSKINSNTIQECRPA-QNGIQSRLTLNQGRPCALGVCE-EGVCKRRVNKLVERIWKIIDEFNTNLFAAFLLENXXXXXXXXXXXXXXPAAILVSCNDAKHRRRFLQERK 2083
            L+D+++LP  +++        +   +   + +SF+   R FKL L  + +L + D K+V +D  G+E    +    +++G V G E S V A +  D+  S +I+ D+  + VEPL R  +   +   +VYR  D++ N +R   PK   +A  ++          +  +++ +    +     +  K  CT+ L+ADYRF R  GR E   T +YLIELID+++ ++++T + D    +  GYG  I+QI+++  PT   +G  HYN E +     K    W V+ LL+ F  DI    S  CLAHLFT+Q F EGTLGLAY+ASS+  + GG+CS+  +  Q+ K  S +NT  ++ ++  GK +++  A LVT HELGHN+GA+HDPD    CAP+  +GGK+VMY  +V G   NN+ FS CS+ S   +                CGNSRV++ EECD G  + + D CCT  C F+  A CS  N  CC+N C F+  G VC  ++ +N  C   S C+G   EC  P ++ +G  C + G C  G+C P+CE   N  +C C++ + SC +CC+D       N +  CRP  QNG    L L +G+PC +G C+  G C ++V  +VER+W  ID+ + N F  FL +N+VG+V++ +LI WIP +I V C    H   F+Q RK
Sbjct:    2 LADFEVLPASSLQKHSVRKREVDAQSHVERLVSFTALKRNFKLYLTSNTELFTEDFKAVFVDNQGKEENFEVPLQNYFKGHVVGEENSRVQAHMDGDE-FSAHILTDEAEYNVEPLWRVTETEPDGRMLVYRSEDIR-NISRLTSPKVCGYASPLAEDLLPAAGAAAGTQQDTEPGHRVRRQTNNPKKNTCTLLLVADYRFFRHMGRREESTTLNYLIELIDRVDDIYRNTSWDD----EYKGYGVQIHQIIINKFPTEVSAGQIHYNMEGSPRSQQKDEQVWDVKKLLEQFSLDIADNASSVCLAHLFTYQDFDEGTLGLAYVASSRDQALGGLCSKPYYPSQSVKKASYLNTGLTSTKN-YGKTILTKEADLVTTHELGHNFGAEHDPDNIPYCAPSDDQGGKFVMYPIAVSGDHVNNKRFSNCSKASPRTS--------------KLCGNSRVEEGEECDPGLLHLNDDPCCTGKCKFRKNAQCSDRNSPCCSN-CHFQQPGKVC--QESINATCKAMSRCTGSSSECPPPGNLPNGTECVDKGVCRRGECVPFCEANKNSRSCACNETDHSCKVCCKD------QNGL--CRPVFQNG--DFLYLRKGKPCTVGFCDGHGKCMKQVQDVVERLWDFIDKLDINTFGKFLADNIVGSVLVFSLIFWIPLSIFVHCVVRTHSALFIQPRK 659          

Query: 1085 NTAWSTYRDAVGKRVISMSAYLVTAHELGHNWGADHDPDTTD-CAPNAARGGKYVMYTYSVVGYEPNNRLFSPCSRRSIGATIATRGEYCFLSPMNAFCGNSRVDDNEECDVG-KNNSADACCTSDCHFKPGAVCSPNNHECCTNDCQFKPYGFVCAAKDPMNP-CVNHSICSGKEKECLGPLS-IDGPNCTEHGRCSSGKCRPYCEQ-LNMEACICDKIEESCLICCRDPPSKINSNTIQECRPAQNGIQSRLTLNQGRPCALGVCE-EGVCKRRVNKLVERIWKIIDEFNTNLFAAFLLENXXXXXXXXXXXXXXPAAILVSCNDAKHRRRF 2068
            N   S  +D    + +   A LVT HELGHN+GA HDPD    CAP+  +GGKYVMY  +V G   NN+LFS CS+ SI   +  +G  CF    +  CGNSRV++ EECD G  + S D CCT+DC  +PG +CS  N  CC N C ++  G  C  ++ +N  C   S C+G   +C  P + +D   C + G+C +G C P+CE  L +++C C++ + SC +CCR        N    C P Q+     L L +G+PC +G C+  G C ++V  ++ER+W  ID+ N N F  FL +N+VG+V+  +L+ WIP +ILV C D K  +++
Sbjct:  274 NMKGSPTKDVWDVKKLLEEADLVTTHELGHNFGAVHDPDDVPYCAPSEDQGGKYVMYPIAVSGDHSNNKLFSNCSKISIVKRLRHKGPSCFKERNSKVCGNSRVEEGEECDPGLLHLSTDPCCTADCKLRPGKLCSDRNSACCKN-CVYEKKGKQC--QEQINATCKGESYCTGTSSKCPPPENLLDKTTCVDSGQCMNGVCIPFCEAFLKLQSCACNETDNSCKVCCR--------NRAGACSPYQDDRGKFLYLRKGKPCTVGFCDGGGKCMKQVQDVIERLWDFIDKLNINTFGKFLADNIVGSVVAFSLVFWIPLSILVHCMDKKLDQQY 596          

Query:  149 ISRSTFDNKKISFSTKFRKFKLILKPSVDLLSNDLKSVNIDRFGRETPVPIDGSQFYQGFVSGAEKSSVSAFLGNDKMLSINIILDDDIFQVEPLSRYVQ--NNSSFIVYRYSDLKGNFTR--GPK-CFAKNISSFE-----TNTTNSRQKRNVDAIISLPYINKDSTKKLCTIKLIADYRFHREHGRGEMGRTQHYLIELIDKINILFKSTDFVDSKNNKNSGYGFIINQILVHVEPTIGPSG--HYNQEVAKQTDAWTVEGLLD 910
            +   T   + +SF+   + F+L L  + +L ++D  ++ I   G      +    F+ G V G E S V A + N+   + +I+ D+  + +EP+ R+++   +   +VYR  D++ N +R   PK C   N  + +         + R+KR V           D +K  C + L+ADYRF R  GR E   T +YLIELID+++ ++++T +    + +  GYG  I QI+V+ +PT    G  H+N + +   D W V+ LL+
Sbjct:   42 VETHTHAERLLSFTALQKHFRLYLATNTELFTDDFNTLVIGEDGTHEVYEVQRENFFTGHVIGEENSRVQAHINNND-FTAHILTDEAEYNIEPMWRFIEGPQDDRLLVYRSEDIR-NVSRLAAPKVCGYINAEATQLLPDGVRAEHLREKRQV----------VDHSKNTCPLLLVADYRFFRNMGRREESTTINYLIELIDRVDDIYRNTSW----DEEFKGYGVQIQQIIVNKDPTPVEPGKAHFNMKGSPTKDVWDVKKLLE 291          

Query:  179 ISFSTKFRKFKLILKPSVDLLSNDLKSVNIDRFGRETPVPIDGSQFYQGFVSGAEKSSVSAFLGNDKMLSINIILDDDIFQVEPLSRYVQNNS---SFIVYRYSDLKGNFTRGPKCFAKNISSFE-------------TNTTN--SRQKRNVDAIISLPYINKDSTKKLCTIKLIADYRFHREHGRGEMGRTQHYLIELIDKINILFKSTDFVDSKNNKNSGYGFIINQILVHVEPTIGPSGHYNQEVAKQTDAWTVEGLLDSFGDIDHKDSCLAHLFTFQSFSEGTLGLAYMASSKTLSYGGICSERDFRHQNSKLVSVNTAWSTYRDAVGKRVISMSAYLVTAHELGHNWGADHDPDTTDCAPNAARG------GKYVMYTYSVVGYEPNNRLFSPCSRRSIGATIATRGEYCFLSPMNAFCGNSRVDDNEECDVGKNNSA-DACC-------TSDCHFKPGAVCSPNNHECCTNDCQFKPYGFVCAAKDPMNPCVNHSICSGKEKECLGPLSIDGPNCTE-HGR---CSSGKCR-PYCEQLNMEACICDKIE-----ESCLICCRDPPSKINSNTIQECRPAQNGIQSRLTLNQGRPC 1855
            + F    R F L ++    L S D K   ++  G E  +  D S  Y G +   + S     + + K     I      F VEP  RY+++       ++Y   D+      GP+    + S FE                TN  S +K + D+++          K  C + +  D+ F + +   E    Q  +   +  I+ +++ TDF+  +N       F++ +I ++       +   ++    +     VE  L+   + +H D CLA++FT + F +G LGLA++ +  + S GGIC E+   + + K  S+NT   T ++     V    +++  AHE+GHN+G+ HD    +C P  ++       G Y+MY  +  G + NN  FS CS R+I   +  +   CF+      CGN  V+  EECD G ++   D CC          C  KP  VCSP+   CCT +C +K     C  +   + C +  +C+G   +C  P S    N T  HG    C +G C    CE+  +E C C  ++     E C +CC +  +    ++    R A+   +   TL  G PC
Sbjct:   66 LQFHAHGRHFNLRMRRDTRLFSEDFK---LEVSGEE--INYDTSHIYSGELFDEQGSITHGSIVDGKFEGF-IKTHRGTFYVEPSERYLEDKKVPFHSVIYHEDDINYPHKYGPEGGCADHSVFERMKKYQVSAVEEPAKETNVVSEKKSSDDSMLLRKKRMTQVEKNTCQLFIQTDHLFFKRYKTREAVIAQ--ISSHVKAIDAIYQGTDFLGIRN-----ISFMVKRIRINT-----TNDERDRSNPFRFANIGVEKFLELNSEQNHDDYCLAYVFTDRDFDDGVLGLAWVGAP-SGSSGGIC-EKSKLYSDGKRKSLNTGIITVQN-YASHVPPKVSHITFAHEVGHNFGSPHD-SGPECTPGESKSQDKKEKGNYIMYARATSGDKLNNNKFSVCSVRNISQVLEKKRGNCFVESGQPICGNGLVEPGEECDCGYSDQCRDLCCYDANQPDNKKCKLKPNKVCSPSQGPCCTPECTYKSRNEKCRDE---SECAHQGMCNGASAQC--PTSEPKANFTACHGETQVCLNGGCSGSICEKYGLEVCTCASVDGKDETELCHVCCMEKANPSTCSSTGSERLARFFNKKVTTLQAGSPC 639          

Query:  116 DYDILPNLNIRISRSTFDNKK---ISFSTKFRKFKLILKPSVDLLSNDLKSVNIDRFGRETPVPIDGSQFYQGFVSGAEKSSVSAFLGNDKMLSINIILDDDIFQVEPLSRYVQNNS---SFIVYRYSDLK--GNFTRGPKCFAKNI---------SSFETNTTNSRQKRNVDAIISLPYINKDSTKKLCTIKLIADYRFHREHGRGEMGRTQHYLIELIDKINILFKSTDFVDSKNNKNSGYGFIINQILVHVEPTIGPSGHYNQEVAKQTDAWTVEGLLDSFGDIDHKDSCLAHLFTFQSFSEGTLGLAYMASSKTLSYGGICSERDFRHQNSKLVSVNTAWSTYRDAVGKRVISMSAYLVTAHELGHNWGADHDPDTTDCAPNAARG------GKYVMYTYSVVGYEPNNRLFSPCSRRSIGATIATRGEYCFLSPMNAFCGNSRVDDNEECDVGKNNS-ADACC-------TSDCHFKPGAVCSPNNHECCTNDCQFKPYGFVCAAKDPMNPCVNHSICSGKEKECLGPLSIDGPNCT----EHGRCSSGKCR-PYCEQLNMEACICDKIE-----ESCLICCRDPPSKINSNTIQECRPAQNGIQSRL------TLNQGRPC 1855
            D D+L + + R  R+     K   + F    R F L +K    L ++DLK   ++  G ETP   D S  Y G + G EK +++     D      I      + VEP  RY++N       ++Y   D+     + R   C   ++         S+ ++      ++R    +I          +  C + +  D+ F + +G  E    Q  +   +  I+ +++STDF   +N       F++ +I ++   T+      N     +     VE  L+   + +H D CLA++FT + F +G LGLA++ +  + S GGIC E+   + + K  S+NT   T ++     V    +++  AHE+GHN+G+ HD    +C P  ++       G Y+MY  +  G + NN  FS CS R+I   +  +   CF+      CGN  V+  E+CD G ++   D CC        + C  K  A CSP+   CCT  C+FK     C     ++ C    +C+G   +C  P S    N T    E   C +G C    CE+ N+E C C   E     E C ICC +   K   NT   CR   +   S        TL  G PC
Sbjct:   50 DTDLLHSHHQRAKRALSHEDKYVHLDFHAHGRHFNLRMKRDTTLFASDLK---VEISGEETPY--DTSHIYTGVLFG-EKGTLTHGSIVDGKFEGFIQSHQGTYYVEPTERYLKNQDVPYHSVIYHEGDIDYPHKYGREGGCADHSVFDRMKKYQASAVDSPAQGEDEERADGPVILRKRRAAQVEQNTCQLFIQTDHLFFKYYGTREAVIAQ--ISSHVKAIDSIYQSTDFQGIRN-----ISFMVKRIRINT--TLDEKDKSN---PFRFANIGVEKFLELNSEQNHDDYCLAYVFTDRDFDDGVLGLAWVGAP-SGSSGGIC-EKSKLYSDGKRKSLNTGIITVQN-YASHVPPKVSHITFAHEVGHNFGSPHD-SGNECTPGESKTQDKKERGNYIMYARATSGDKFNNNKFSICSIRNISQVLDKKRGLCFVESGQPICGNGLVEPGEQCDCGYSDQCKDECCHHANKPEGTKCTLKEEAKCSPSQGPCCTTKCEFKSSDEKCRN---VSECAEEGMCNGVSAQC--PTSTPKQNFTACHSETQVCINGVCTGSICERFNLEMCTCAVEEGQDETELCHICCME---KGKPNT---CRSTGSAEWSDFFDKKVRTLQPGSPC 643          

Query:  110 LSDYDILP--NLNIRISRSTFD----NKKISFSTKFRKFKLILKPSVDLLSNDLKSVNIDRFGRETPVPIDGSQFYQGFVSGAEKSSVSAFLGNDKMLSINIILDDDIFQVEPLSRYVQN--NSSFIVYRYSDLKGNF-----TRGPKCFAKNISSFETNTTNSRQKRNVDAIISLPYINK--DSTKKLCTIKLIADYRFHREHGRGEMGRTQHYLIELIDKINILFKSTDFVDSKNNKNSGYGFIINQILVHVEPTI--GPSGHYNQE---------------VAKQTDAWTVEGLLDSFG-DIDHKDS--CLAHLFTFQSFSEGTLGLAYMASSKTLSYGGICSERDFRHQNSKLVSVNTAWSTYRDAVGKRVISMSAYLVTAHELGHNWGADHDPDTTDCAPNAARGGKYVMYTYSVVGYEPNNRLFSPCSRRSIGATIATRGEYCFLSPMNAFCGNSRVDDNEECD----VGKNNSADACCTSDCHFKPGAVCSPNNHECCTNDCQFKPYGFVCAAKDPMNPCVNHSICSGKEKECLGPLSI-DGPNCTEHGRCSSGKCRPYCEQLN--MEACICDKIEESCLICCRDPPSKINSNTIQECRPAQNGIQSRLTLNQGRPCALGVCE-EGVCKRRVNKLVERIWKIIDEFNTNLFAAFLLENXXXXXXXXXXXXXXPAAILVSCND 2047
            L  YD+L   ++  RISR        ++ +SF    RKF L L     LL++  + +  D +G   P+P++   FY G+V G   SSV A++G  +  S  I+   D + VEPL R   +  +   +VYR   L+G+      TR P+  AK     E         +   +  S   +    +  K  CT+ L+AD+RF +  GRG+ G T +YLIEL+D+++ +F+ T +      + +  G  I +IL+H E T+  G   HYN E               +   + AW V  LL  F  D+  + S  CLAHLFT+Q F +G LGLAY+AS    + GG+CS+R  + +N   VS NT  ++  +  GK +++    LV AHELGH++GA HD  T +C+      GKY+MY  +V G +PNN LFSPCS RS+G  ++ +   C     + +CGN RV+D E+CD    +G+N+S   CCT +C  +  A+CS  N  CC   C++K    +C  + P   C   + C+G    C  P ++ DG  C +HGRC SG C+P+C  L   +E C+C +  +SC +CCR P           C P      S L L +G+PC++G C+  G C ++V   +ER W  I++ N N  + FL +N+VG+V+I +++LW+P ++LV C D
Sbjct:   30 LRHYDLLSLSHMEHRISRRDVAEGPRDRTVSFQALGRKFVLHLSARRGLLTDSARVLMQDAWGEVKPLPLNTHGFYSGYVQGDSNSSVQAYIGEGE-FSARILTSGDEYHVEPLWRLAGDPEDERMVVYRGDALQGSHAPFCATRLPR-GAKKGGEQEGRRPGEHPGQQFGSTNSGGPVGAMGEPVKDTCTLLLVADFRFFQAMGRGQQGTTINYLIELVDRVDGIFRGTHW----GEQAASVGIQIQEILIHEESTVVVGGERHYNMEAPPSPITHGLPSPPSLGTTSHAWNVSELLRQFSMDVSERASQVCLAHLFTYQDFEDGILGLAYVASPTGKTDGGVCSKR-VQEKNGINVSYNTGLTSTMN-YGKTILTKEVELVVAHELGHSFGAGHD--TEECSAGHDADGKYIMYPIAVSGDQPNNGLFSPCSVRSVGQVLSHKAASCLTPQRHKYCGNFRVEDGEQCDEGPPLGRNHS---CCTHNCTLRENALCSDRNSPCCQG-CRYKDQ-VLCQGRLPAL-CREAAFCTGDSGVCPKPGNLSDGTECLDHGRCLSGVCQPFCTTLEQKLEPCVCAEKNDSCKVCCRRPGGG--------CAPYLAAGGSPLLLPRGKPCSVGFCDIHGQCIKQVQDFLERTWDFIEKLNANELSRFLADNVVGSVLIFSVLLWVPLSLLVHCVD 694          

Query: 1028 GGICSERDFRHQNSKLVSVNTAWSTYRDAVGKRVISMSAYLVTAHELGHNWGADHDPDTTDCAPNAAR------GGKYVMYTYSVVGYEPNNRLFSPCSRRSIGATIATRGEYCFLSPMNAFCGNSRVDDNEECDVG-KNNSADACC-------TSDCHFKPGAVCSPNNHECCTNDCQFKPYGFVCAAKDPMNPCVNHSICSGKEKECLGPLSIDGPNCTEHGR--CSSGKCR-PYCEQLNMEACIC--DKIEESCLICCRDP--PSKINSNTIQECRPAQNGIQSRLTLNQGRPC 1855
            GGIC ER+    +    S+NT   T  +  G  V    + +   HE+GHN+G+ HD +   C P  ++       G Y+MY Y+  G +PNN LFSPCS  SI   +  +   CF+      CGN  V+++EECD G + +  D CC          C  +P   CSP+   CC+++C+    G +C    P   C    +CSG    CL     D       G   C  G C    CE   +E C C  +  E  C ICC +P   S     + +  R   NG  SR+ L  G PC
Sbjct:    5 GGIC-ERNKLFSDRTRKSLNTGIVTVNN-YGSHVPLKVSIITITHEVGHNFGSPHDSEAR-CMPGESQERAQRTAGNYLMYPYAQSGDKPNNMLFSPCSVDSISKVLKAKRNLCFIESDTPVCGNGLVEEDEECDCGFEEDCVDLCCFPASAPAGQRCRLRPDVECSPSEGPCCSHECKLHAAGKLC---RPEAECSKAGVCSGDMVICLASEPKDNHTVCNRGSQICMQGLCSGSICELYGLEECHCPGESPEAQCHICCSNPGESSSCAGTSAERWRRYFNG--SRVALQPGSPC 293          

Query:  947 AHLFTFQSFSEGTLGLAYMASSKTLSYGGICSERDFRHQNSKLVSVNTAWSTYRDAVGKRVISMSAYLVTAHELGHNWGADHD-PDTT-DCAPNAARGGKYVMYTYSVVGYEPNNRLFSPCSRRSIGATIATRGEYCFLSPMNAF-------CGNSRVDDNEECDVGKNNSAD-ACCTS-DCHFKPGAVCSPNNHECCTNDCQFKPYGFVCAAKDPMNPCVNHSICSGKEKECLGPLS-IDGPNCTEHGR---CSSGKCRPYCEQ 1696
            A L T  SF   T+G+A + S        +CS      + S  V+++ A +          + ++A +  AHE+GHN+G +HD P+    C  N+ +GG  +  +       P    FS CS R + ++++  G  C  +  +         CGN  V+D E+CD G+    D  CC + +C  + GA C+   H  C  DCQ KP G  C  +DP N C     C+G    C   +  +DG  C  HG+   C +G C  + +Q
Sbjct:  165 AQLVTGISFQGTTIGMAPLMS--------MCSA-----EQSGGVNMDHAVNP---------VGLAATM--AHEMGHNFGMNHDTPERRCHCQANSEQGGCIMAPSTG----HPFPSKFSSCSIRDLDSSLSKGGGMCLYNMPDVRDLYGGKRCGNGYVEDGEQCDCGEIEECDNPCCNANNCTLRAGAECA---HGMCCQDCQLKPSGTRC--RDPTNTCDLPEYCNGGSPHCPPNVYLLDGYPC--HGKEAYCYNGMCLTHEQQ 394          

Query: 1157 AHELGHNWGADHD-PDTT-DCAPNAARGGKYVMYTYSVVGYEPNNRLFSPCSRRSIGATIATRGEYCFLSPMNAF-------CGNSRVDDNEECDVGKNNSAD-ACCTS-DCHFKPGAVCSPNNHECCTNDCQFKPYGFVCAAKDPMNPCVNHSICSGKEKECLGPLS-IDGPNCTEHGR---CSSGKCRPYCEQ 1696
            AHE+GHN+G +HD P+    C  N+ +GG   +   S  G    N  FS CS R + ++++  G  C  +  +         CGN  V+D E+CD G+    D  CC + +C  + GA C+   H  C  DCQ KP G  C  +DP N C     C+G    C   +  +DG  C  HG+   C +G C  + +Q
Sbjct:  213 AHEMGHNFGMNHDTPERRCHCQANSEQGG--CIMAPSTGG----NDKFSSCSIRDLDSSLSKGGGMCLYNMPDVRDLYGGKRCGNGYVEDGEQCDCGEIEECDNPCCNANNCTLRAGAECA---HGMCCQDCQLKPSGTRC--RDPTNTCDLPEYCNGGSPHCPPNVYLLDGYPC--HGKEAYCYNGMCLTHEQQ 394          

Query:  887 WTVEGLLDSFGDIDHKDSCLAHLFTFQSFSEGTLGLAYMASSKTLSYGGICSERDFRHQNSKLVSVNTAWSTYRDAVGKRVISMSAYLVTAHELGHNWGADHDPDTTDCAPNA-ARGGKYVMYTYSVVGYEPNNRLFSPCSRRSIGATIATRGEYCFLS---PMNAF----CGNSRVDDNEECDVGKNNSADACC--TSDCHFKPGAVCSPNNHECCTNDCQ 1522
            W +  LL       H D+  AHL T   FS+  +G+A +++  T    G  S     H  S L   +T                      AHE+GHN G +HD     C  +A A  G  +M      G+ P  ++FS CSR+ +  ++      C  +   P + +    CGN  V+  EECD G     +  C   S C  K GA C+      C  DCQ
Sbjct:  225 WRMTNLLPR----KHNDN--AHLLTGGVFSDSAIGMAPVSTMCTKDRSGGIS---IDHSTSALAVAST---------------------MAHEVGHNLGMNHDMPERGCVCSASANKGGCIM--EPATGFTP-GQVFSSCSRKDLQGSLQQGVGMCLFNVPGPGDLYGGPHCGNQYVEVGEECDCGTVQECNNVCCDASTCMLKKGAQCAEG---LCCKDCQ 410          

Query:  278 GRETPVPIDGSQFYQGFVSGAEKSSVSAFLGNDKMLSINIILDDDIFQVEPLSRYVQNNS-SFIVYRYSDL--KGNFTRGPKCFAKNISSFETNTTNSRQKRNVDAIISLPYINKDSTKKL--CTIKLIADYRFHREHGRGEMGRTQHYLIELIDKINILFKSTDFVDSKNNKNSGYG--FIINQILVHVEPTIGPSGHYNQEVAKQTDAWTVEGLLDSFGDIDHKDSCLAHLFTFQSFSEGTLGLAYMASSKTLSYGGICSERDFRHQNSKLVSVNTAWST---YRDAVGKRVISMSAYLVTAHELGHNWGADHDPDTTDCAPNAARGGKYVMYTYSVVGYEPNNRLFSPCSRRSIGATI-ATRGEY----CFLSPMNAFCGNSRVDDNEECDVGKNNSADA---CCT-----SDCHFKPGAVCSPNNHECCTNDCQFKPYGFVCAAKDPMNPCVNHSICSGKEKECLGPLSIDGPNCT--EHGR--CSSGKC-RPYCEQLNMEACICDKIEESCLICCRDPPSKINSNTIQECRPAQNGIQ-----SRLTLNQGRPCA--LGVCEE-GVCKRR-----VNKLVERIWKI--IDEFNTNLFAAFLL 1969
            G  TP+ ID +    G V G   S+V   + + K     I  + + F VEP  RY        ++YR  D+  KGN+            S +      R+KR  D+    P    +  KKL  CT+ L AD+ F +  G     R    L E I  + I++K+  F  +  +  S YG  F + +++++ E  + P  + +  +A       ++ +L+     DH D C A +FT + F  G LGLA++     L  GGICS   +     + +S NT   T   YR     +V    + +  AHELGH +G++HDP+  DC+P   + G YVMY+ +  G  PNN +FS CS ++I   I   RG+     CF+S     CGN  ++ NE+CD G  NS  A   CC        C     A CSP+   CC  DC++      C  K     C++ ++CSG   EC  P S+  P+ T  + GR  CS G+C +  C +  +E C C    + C +CC++P           C P ++  Q       L  + G PCA   G C+   VC+R      + +L E+ + +  + E     + A LL
Sbjct:   85 GDGTPLDIDMNSMVAGEVVGEPGSAVYGTMEDGKFQG-KIQSNTESFYVEPSERYFDKPEFHSVIYRSEDVENKGNYAD---------MSMKMPEILDREKR--DSGEDRPRRATEQEKKLDSCTLALYADHLFTKLCG--GKSRAVFKLTEHITAVQIIYKNA-FNTTNYDLYSPYGITFRVKKMVIYDEQDV-PDKYKDDNLA-------IDVMLNLLSSDDHSDVCEAFMFTDRDFDNGILGLAWIGKPNFL--GGICSR--YSKVGGQYISYNTGVVTLKLYRLFTPPKV----SEVTFAHELGHGFGSEHDPEDGDCSP-GGKDGNYVMYSKATSGDRPNNDVFSSCSLKAIRDNINDKRGDPKYSGCFISADTPICGNRIIEGNEQCDCGDENSCKAEGGCCNPPGHPQACRLTLPATCSPSQGPCCGRDCRYVGNDISCRNK---TDCLDKAMCSGSSVEC--PKSVYQPDNTVCDKGRRVCSVGECAKSICTKYALEECQCTADNDLCTVCCKEP------GRDDTCTPTRDKTQLPKQVHGLMKSAGSPCANMHGYCDAFAVCRRLDLDGPLKRLKEKFFTVKGLKELVKEKWWAILL 648          

Query:  179 ISFSTKFRKFKLILKPSVDLLSNDLKSVNIDRFGRETPVPIDGSQFYQGFVSGAEKSSVSAFLGNDKMLSINIILDDDIFQVEPLSRYVQNNSSF--IVYRYSDLKGNFTRGPKC-FAKNISSFETNTTNS-------------------RQKRNVDAIISLPYINKDSTKKLCTIKLIADYRFHREHGRGEMGRTQHYLIELIDKINILFKSTDFVDSKNNKNSGYGFIINQILVHVEPTIGPSGHYNQEVAKQTDAWTVEGLLD-SFGDIDHKDSCLAHLFTFQSFSEGTLGLAYMASSKTLSYGGICSERDFRHQNSKLVSVNTAWSTYRDAVGKRVISMSAYLVTAHELGHNWGADHDPDTTDCAPNAARGGKYVMYTYSVVGYEPNNRLFSPCSRRSIGATIATRG-----EYCFLSPMNAFCGNSRVDDNEECDVGKNN----SADACC-------TSDCHFKPGAVCSPNNHECCTNDCQFKPY----GFVCAAKDPMNPCVNHSICSGKEKECLGPLSIDGPNCT--EHGR--CSSGKCR-PYCEQLNMEACICDKIEESCLICCR--DPPSKINSNTIQECRPAQNGIQSRLTLNQGRPC 1855
            ++F    RKFKL L+    + ++DL   N + F        D S+   G V G +KS V  F+  D +    I + DD + VE  S+Y +    F  ++Y    ++  +  G  C  +  I  +      S                   R +R    I        D TKK C + + AD+ +     +    R    + + +  I  +++ TDF D   N +    F+I + LV+     G S   NQ+   +     V  LL+ +     ++  CL+++FT++ F +G LGLA++  + T S GGIC          K++  NT   T+ +  GK V    + +  AHE GHN+G+ HDP+ T         G Y+M+  +  G + NNR FS CSR  +   +  +G     + CF     A CGN  V++ E CD G  +    +AD CC        + C +K GA CSP+   CC  D    PY     F+C  +     C N S C+G    C  PL    P+ T  E GR  C +G C+   C +   + C C    + C +CC   D   K  S+  +          + +TL+ G PC
Sbjct:   41 LNFLAHERKFKLRLRRDTSIFADDLVVENYNDF--------DPSKVVAGEVLGHKKSLVHGFI-LDGVFEGKIHIGDDEYHVEHSSKYFKEKQPFHSVIYHTQAVEYPYPYGRGCGLSDKIQEWMQKVQRSAMPDADLEGDHSKFEPVLHRYRRAASGI--------DPTKKTCRLYMQADHLYTEHVAQNSKERAILQMTDHVRAIKAIYQGTDF-DGDGNADL-ITFVIQRFLVN-----GSSEASNQDNPFRNANIGVAKLLELNSQQKKNEGYCLSYIFTYRDFDDGVLGLAWVGDTTTGSSGGICENWKSFTDGHKIL--NTGVVTFIN-YGKDVPQKVSEITFAHEAGHNFGSPHDPEITSACSPGDSDGNYIMFPRATSGEKSNNRKFSTCSRDKMYLVLQAKGICDQEKCCFKDSQEAICGNRVVEEGESCDCGYQDDASCTADKCCLGSNVQAKTGCTYKNGATCSPSQGLCCNGD-TCSPYPGNSTFLCQNE---TECRNQSFCNGINATC--PLGEPKPHHTICEDGRKLCINGTCQGSICMKYGYKECQCTAEPKQCDLCCDVGDGECKSTSDIAE---------MTTMTLHAGSPC 607          

Query: 1085 NTAWSTYRDAVGKRVISMSAYLVTAHELGHNWGADHDPDTTDCAPNAARGGKYVMYTYSVVGYEPNNRLFSPCSRRSIGATIATRGEYCFLSP-MNAFCGNSRVDDNEECDVG---KNNSADACC--------TSDCHFKPGAVCSPNNHECCTNDCQFKPYGFVCAAKDPMNPCVNHSICSGKEKECLGPLSIDGPNCTEHG----RCSSGKC-RPYCEQLNMEACICDKIEESCLICCR 1756
            NTA  + ++  G RV+   + L TAHELGH++G++HDPD T C P     G ++MY  +V G +PNN LFS CS+  + + I  +G  CF++    AFCGNS V+  EECD G   + +  D CC          +C  KP   CSP    CC ++C    +            C   + CS      + P  I  P  T  G     C  G C  P C +  ++ C C   ++ CL+CCR
Sbjct:    3 NTAVVSLKN-FGARVLRKGSVLTTAHELGHSFGSEHDPDNTLCRPE-GEPGYFIMYDLAVDGKKPNNFLFSECSKAQMWSVIFNKGPKCFIAQNQGAFCGNSIVEGGEECDCGAPQRCSEVDVCCHPGNITSGIPECRVKPEYQCSPQKGLCCESNCTLSAH----------KTCRKETECSYAGATAVCPEPIPKPRNTTCGDDGNTCLDGACVGPVCARYFLDQCECQGQDQMCLVCCR 231          

Query:  710 LIELIDKINILFKSTDFVDSKNNKNSGYGFIINQILVHVEPTIGPSGHYNQEVAKQTDAWTVEGLLD-SFGDIDHKDSCLAHLFTFQSFSEGTLGLAYMASSKTLSYGGICSERDFRHQNSKLVSVNTAWSTYRDAVGKRVISMSAYLVTAHELGHNWGADHDPD-TTDCAPNAARGGKYVMYTYSVVGYEPNNRLFS 1297
            + + +  I  +++ TDF D   N +    F+I + LV+     G S   NQ+   +     V  LL+ +     ++  CL+++FT++ F +G LGLA++  + T S GGIC          K++  NT   T+ +  GK V    + +  AHE GHN+G+ HDP+ T+ C+P  +  G Y+M+  +  G + NNR FS
Sbjct:    9 MTDHVRAIKAIYQGTDF-DGDGNADL-ITFVIQRFLVN-----GSSEASNQDNPFRNANIGVAKLLELNSQQKKNEGYCLSYIFTYRDFDDGVLGLAWVGDTTTGSSGGICENWKSFTDGHKIL--NTGVVTFIN-YGKDVPQKVSEITFAHEAGHNFGSPHDPEITSACSPGDSD-GNYIMFPRATSGEKSNNRKFS 195          

Query:  110 LSDYDILPNLNIR--------ISRSTFDNKKISFSTKFRKFKLILKPSVDLLSNDLKSVNIDRFGRETPVPIDGSQFYQGFVSGAEKSSVSAFLGNDKMLSINIILDDDIFQVEPLSRYVQN--NSSFIVYRYSDLKGNFTR--GPKC-------------FAKNISSFETNTTNSRQKRNVDAIISLPYINKDSTKKLCTIKLIADYRFHREHGRGEMGRTQHYLIELIDKINILFKSTDFVDSKNNKNSGYGFIINQILVHVEPTIGPSG-------HYNQEVAKQ--TDAWTVEGLLDSFG-DIDHKDS--CLAHLFTFQSFSEGTLGLAYMASSKTLSYGGICSERDFRHQNSKLVS-VNTAWSTYRDAVGKRVISMSAYLVTAHELGHNWGADHDPDTTD-CAPNAARGGKYVMYTYSVVGYEPNNRLFSPCSRRSIGATIATRGEYCFLSPMNAFCGNSRVDDNEECDVG-KNNSADACCTSDCHFKPGAVCSPNNHECCTNDCQFKPYGFVCAAKDPMNP-CVNHSICSGKEKECLGPLSI-DGPNCTEHGRCSSGKCRPYCEQL-NMEACICDKIEESCLICCRDPPSKINSNTIQECRPAQNGIQSRLTLNQGRPCALGVCE-EGVCKRRVNKLVERIWKIIDEFNTNLFAAFLLENXXXXXXXXXXXXXXPAAILVSCNDAKHRRRFLQERK 2083
            LSDY++LP   ++        +   +   + +SF    R F+L L  + DL +   K+V +D+ G E    +    F+ G V G E S V A +  D+  S +I+ ++D + +EPL R+ ++  +   + YR  D+K N +R   PK               +   S  + +  + R+KR             D  K  C + L+ADYRFH++ GRG+   T +YLIELID+++ ++++T +    + +   YG  INQI+++ EPT  P G       HYN + +     + W V+ LL+ F  DI    S  CLAHLFT+Q F EGTLGLAY+A SK  + GG+CS   +   +SK  S +NT  ++ ++  GK +++  A LVT HELGHN+GA+HDPD    CAP+   GGK+VMY  +V G   NN+ FS CS+ S+G T+ ++   CF    +  CGNSRV++ E+CD G  N + D CCT DC FKP A CS  N  CC N CQFK  G  C  ++P+N  C   S C+G   EC  P +  D   C + G+C +G+C P+CE + N  +C C++ + SC +CC+D       N    C P      S L L +G+PC +G C+  G C ++V  ++ER+W  ID+ + N F  FL +N+VG+V++ +LI WIP +ILV C D +  +++ + ++
Sbjct:   36 LSDYEVLPFSGLQQHSVRKRDVQTHSHLERLVSFRALNRDFQLYLTTNTDLFTEKFKAVIVDKHGNEKNFDVPLQNFFTGHVVGEENSRVQAHIDADE-FSAHILTNEDEYNIEPLWRFTESPKDDRLLFYRSDDIK-NLSRIASPKVCGYVKAEDNDLLPHSSRRSWEDQDEHHHREKRQA----------HDHKKNTCPLLLVADYRFHQQMGRGQESVTINYLIELIDRVDDIYRNTTW----DEEYIDYGVQINQIIINKEPTKPPPGRASSRWVHYNMKDSPDGGREVWDVKKLLEQFSSDIADNASAVCLAHLFTYQDFDEGTLGLAYVAPSKPQALGGLCSRPYYPSASSKKASYLNTGLTSTKN-YGKTILTKEADLVTTHELGHNFGAEHDPDNIPYCAPSDNEGGKFVMYPIAVSGDHVNNKRFSNCSKISVGKTLRSKAPLCFKERNSKVCGNSRVEEGEQCDPGLLNLNKDPCCTPDCQFKPTAKCSDTNSLCCKN-CQFKARGERC--QEPINATCKGISSCTGNSSECPPPENAPDNTVCVDSGQCRNGECHPFCEAIQNSHSCACNETDNSCKVCCKD------KNGF--CSPVTQADGSFLYLRKGKPCTVGFCDGNGKCMKQVQDVIERLWDFIDKLDINTFGKFLADNIVGSVVVFSLIFWIPLSILVHCMDKRLDQQYEESKR 709          

Query:  110 LSDYDILPNLNIR--------ISRSTFDNKKISFSTKFRKFKLILKPSVDLLSNDLKSVNIDRFGRETPVPIDGSQFYQGFVSGAEKSSVSAFLGNDKMLSINIILDDDIFQVEPLSRYVQN--NSSFIVYRYSDLKGNFTR--GPKC-------------FAKNISSFETNTTNSRQKRNVDAIISLPYINKDSTKKLCTIKLIADYRFHREHGRGEMGRTQHYLIELIDKINILFKSTDFVDSKNNKNSGYGFIINQILVHVEPTIGPSG-------HYNQEVAKQ--TDAWTVEGLLDSFG-DIDHKDS--CLAHLFTFQSFSEGTLGLAYMASSKTLSYGGICSERDFRHQNSKLVS-VNTAWSTYRDAVGKRVISMSAYLVTAHELGHNWGADHDPDTTD-CAPNAARGGKYVMYTYSVVGYEPNNRLFSPCSRRSIGATIATRGEYCFLSPMNAFCGNSRVDDNEECDVG-KNNSADACCTSDCHFKPGAVCSPNNHECCTNDCQFKPYGFVCAAKDPMNP-CVNHSICSGKEKECLGPLSI-DGPNCTEHGRCSSGKCRPYCEQL-NMEACICDKIEESCLICCRDPPSKINSNTIQECRPAQNGIQSRLTLNQGRPCALGVCE-EGVCKRRVNKLVERIWKIIDEFNTNLFAAFLLENXXXXXXXXXXXXXXPAAILVSCNDAKHRRRFLQERK 2083
            LSDY++LP   ++        +   +   + +SF    R F+L L  + DL +   K+V +D+ G E    +    F+ G V G E S V A +  D+  S +I+ ++D + +EPL R+ ++  +   + YR  D+K N +R   PK               +   S  + +  + R+KR             D  K  C + L+ADYRFH++ GRG+   T +YLIELID+++ ++++T +    + +   YG  INQI+++ EPT  P G       HYN + +     + W V+ LL+ F  DI    S  CLAHLFT+Q F EGTLGLAY+A SK  + GG+CS   +   +SK  S +NT  ++ ++  GK +++  A LVT HELGHN+GA+HDPD    CAP+   GGK+VMY  +V G   NN+ FS CS+ S+G T+ ++   CF    +  CGNSRV++ E+CD G  N + D CCT DC FKP A CS  N  CC N CQFK  G  C  ++P+N  C   S C+G   EC  P +  D   C + G+C +G+C P+CE + N  +C C++ + SC +CC+D       N    C P      S L L +G+PC +G C+  G C ++V  ++ER+W  ID+ + N F  FL +N+VG+V++ +LI WIP +ILV C D +  +++ + ++
Sbjct:   36 LSDYEVLPFSGLQQHSVRKRDVQTHSHLERLVSFRALNRDFQLYLTTNTDLFTEKFKAVIVDKHGNEKNFDVPLQNFFTGHVVGEENSRVQAHIDADE-FSAHILTNEDEYNIEPLWRFTESPKDDRLLFYRSDDIK-NLSRIASPKVCGYVKAEDNDLLPHSSRRSWEDQDEHHHREKRQA----------HDHKKNTCPLLLVADYRFHQQMGRGQESVTINYLIELIDRVDDIYRNTTW----DEEYIDYGVQINQIIINKEPTKPPPGRASSRWVHYNMKDSPDGGREVWDVKKLLEQFSSDIADNASAVCLAHLFTYQDFDEGTLGLAYVAPSKPQALGGLCSRPYYPSASSKKASYLNTGLTSTKN-YGKTILTKEADLVTTHELGHNFGAEHDPDNIPYCAPSDNEGGKFVMYPIAVSGDHVNNKRFSNCSKISVGKTLRSKAPLCFKERNSKVCGNSRVEEGEQCDPGLLNLNKDPCCTPDCQFKPTAKCSDTNSLCCKN-CQFKARGERC--QEPINATCKGISSCTGNSSECPPPENAPDNTVCVDSGQCRNGECHPFCEAIQNSHSCACNETDNSCKVCCKD------KNGF--CSPVTQADGSFLYLRKGKPCTVGFCDGNGKCMKQVQDVIERLWDFIDKLDINTFGKFLADNIVGSVVVFSLIFWIPLSILVHCMDKRLDQQYEESKR 709          

Query:   89 FGDWQNQLSDYDILPNLNIR--------ISRSTFDNKKISFSTKFRKFKLILKPSVDLLSNDLKSVNIDRFGRETPVPIDGSQFYQGFVSGAEKSSVSAFLGNDKMLSINIILDDDIFQVEPLSRYVQN--NSSFIVYRYSDLKGNFTRGPKCFAKNISSFETNTTNSRQKRNVDAIISLPYINK---DSTKKLCTIKLIADYRFHREHGRGEMGRTQHYLIELIDKINILFKSTDFVDSKNNKNSGYGFIINQILVHVEPT-IGPS-GHYNQE--VAKQTDAWTVEGLLDSFG-DIDHK--DSCLAHLFTFQSFSEGTLGLAYMASSKTLSYGGICSERDFRHQNSK-LVSVNTAWSTYRDAVGKRVISMSAYLVTAHELGHNWGADHDPD-TTDCAPNAARGGKYVMYTYSVVGYEPNNRLFSPCSRRSIGATIATRGEYCFLSPMNAFCGNSRVDDNEECDVGK-NNSADACCTSDCHFKPGAVCSPNNHECCTNDCQFKPYGFVCAAKDPMNP-CVNHSICSGKEKECLGPLSI-DGPNCTEHGRCSSGKCRPYCEQ-LNMEACICDKIEESCLICCRDPPSKINSNTIQECRPAQNGIQSRLTLNQGRPCALGVCE-EGVCKRRVNKLVERIWKIIDEFNTNLFAAFLLENXXXXXXXXXXXXXXPAAILVSCNDAKHRRRFLQERKS 2086
            F   ++ L D+D+LP  +++        +   T   K +SFS   R F+L L+ + +L S D  +V +   GRE   P++   F+ G V G E S V A + N +  S +I+ D+  + +EPL R+     +   ++YR  D++ N +R  +       S           ++     S P   +   D  K  C + L+ADYRF    GRGE   T +YLIELID+++ ++++T    S + + SGYG  I QI++   PT + P   H+N      +  D W V+ LL+ F  DI  K  + CLAHLFT+Q F EGTLGLAY+A SK    GG+CS+      N    + +NT  ++ ++  GK +++  A LVT HELGHN+GA+HDPD   DCAP   +GGKYVMY  +V G + NN+LFS CS+RSI   + ++   CF       CGNSRV+  EECD G  N S D CCT DC  + GA CS  N  CC N C+F   G VC  ++P+N  C  HS C+G   EC  P +  D   C ++G C +G+C P+C+  LN++ C C++   SC +CCR      NS  +  C P ++   + + L +G+PC +G C+  G C ++V  +VER+W  ID+ + N F  FL +N+VG+V+  +L+ W+P +ILV   D K  +++ Q  KS
Sbjct:   37 FASLRSILEDFDVLPFSSLQSHSVRRREVQTQTHVEKVLSFSALHRNFQLYLRTNEELFSKDFSAVVVGEDGREHNHPVNRQTFFTGHVIGEENSRVQAHIDNQE-FSAHILTDEAEYNIEPLWRFTSTPPDGRVLIYRSEDIR-NISRLQQPAVCGYVSPALTDGRRAAVQDEQEEGSGPRSRRQLHDHRKNTCPLLLVADYRFFMHMGRGEESTTLNYLIELIDRVDDIYRNT----SWDEEFSGYGVQIQQIIIESGPTPVAPGKSHFNMRGSPVEGKDVWDVKKLLEQFSVDIADKAFNVCLAHLFTYQDFDEGTLGLAYVAPSKPDIPGGLCSKACPSSTNQHGAIYLNTGLTSTKN-YGKTILTKEADLVTTHELGHNFGAEHDPDDILDCAPREDQGGKYVMYPIAVSGDQVNNKLFSNCSKRSIVKRLRSKATSCFRERNINVCGNSRVEQGEECDPGLINISLDGCCTPDCRLREGAQCSDRNSACCKN-CRFASRGVVC--QEPINATCEGHSYCTGDSSECPAPENAPDKTVCLDNGECHNGECVPFCQAILNLQPCACNETNSSCKVCCR------NSGGV--CLPYKDKSDNFVFLRKGKPCTVGFCDGAGKCMKQVQDVVERLWYFIDKLDINTFGKFLADNIVGSVVAFSLLFWVPVSILVHFVDKKLDKQYEQTAKS 711          

Query:  125 ILPNLNIR---ISRSTFDNKKISFSTKFRKFKLILKPSVDLLSNDLKSVNIDRFGRETPVPIDGSQFYQGFVSGAEKSSVSAFLGNDKMLSINIILDDDIFQVEPLSRYVQN--NSSFIVYRYSDLKGNFTRGPKCFAKNISSFETNTTNSRQKRNVDAIISLPYINK---DSTKKLCTIKLIADYRFHREHGRGEMGRTQHYLIELIDKINILFKSTDFVDSKNNKNSGYGFIINQILVHVEPT-IGPS-GHYNQE--VAKQTDAWTVEGLLDSFG-DIDHK--DSCLAHLFTFQSFSEGTLGLAYMASSKTLSYGGICSERDFRHQNSK-LVSVNTAWSTYRDAVGKRVISMSAYLVTAHELGHNWGADHDPD-TTDCAPNAARGGKYVMYTYSVVGYEPNNRLFSPCSRRSIGATIATRGEYCFLSPMNAFCGNSRVDDNEECDVGK-NNSADACCTSDCHFKPGAVCSPNNHECCTNDCQFKPYGFVCAAKDPMNP-CVNHSICSGKEKECLGPLSI-DGPNCTEHGRCSSGKCRPYCEQ-LNMEACICDKIEESCLICCRDPPSKINSNTIQECRPAQNGIQSRLTLNQGRPCALGVCE-EGVCKRRVNKLVERIWKIIDEFNTNLFAAFLLENXXXXXXXXXXXXXXPAAILVSCNDAKHRRRFLQERKS 2086
            IL + ++R   +   T   K +SFS   R F+L L+ + +L S D  +V +   GRE   P++   F+ G V G E S V A + N +  S +I+ D+  + +EPL R+     +   ++YR  D++ N +R  +       S           ++     S P   +   D  K  C + L+ADYRF    GRGE   T +YLIELID+++ ++++T +    + + SGYG  I QI++   PT + P   H+N      +  D W V+ LL+ F  DI  K  + CLAHLFT+Q F EGTLGLAY+A SK    GG+CS+      N    + +NT  ++ ++  GK +++  A LVT HELGHN+GA+HDPD   DCAP   +GGKYVMY  +V G + NN+LFS CS+RSI   + ++   CF       CGNSRV+  EECD G  N S D CCT DC  + GA CS  N  CC N C+F   G VC  ++P+N  C  HS C+G   EC  P +  D   C ++G C +G+C P+C+  LN++ C C++   SC +CCR      NS  +  C P ++   + + L +G+PC +G C+  G C ++V  +VER+W  ID+ + N F  FL +N+VG+V+  +L+ W+P +ILV   D K  +++ Q  KS
Sbjct:   23 ILQSHSVRRREVQTQTHVEKVLSFSALHRNFQLYLRTNEELFSKDFSAVVVGEDGREHNHPVNRQTFFTGHVIGEENSRVQAHIDNQE-FSAHILTDEAEYNIEPLWRFTSTPPDGRVLIYRSEDIR-NISRLQQPAVCGYVSPALTDGRRAAVQDEQEEGSGPRSRRQLHDHRKNTCPLLLVADYRFFMHMGRGEESTTLNYLIELIDRVDDIYRNTSW----DEEFSGYGVQIQQIIIESGPTPVAPGKSHFNMRGSPVEGKDVWDVKKLLEQFSVDIADKAFNVCLAHLFTYQDFDEGTLGLAYVAPSKPDIPGGLCSKACPSSTNQHGAIYLNTGLTSTKN-YGKTILTKEADLVTTHELGHNFGAEHDPDDILDCAPREDQGGKYVMYPIAVSGDQVNNKLFSNCSKRSIVKRLRSKATSCFRERNINVCGNSRVEQGEECDPGLINISLDGCCTPDCRLREGAQCSDRNSACCKN-CRFASRGVVC--QEPINATCEGHSYCTGDSSECPAPENAPDKTVCLDNGECHNGECVPFCQAILNLQPCACNETNSSCKVCCR------NSGGV--CLPYKDKSDNFVFLRKGKPCTVGFCDGAGKCMKQVQDVVERLWYFIDKLDINTFGKFLADNIVGSVVAFSLLFWVPVSILVHFVDKKLDKQYEQTAKS 680          

Query:  179 ISFSTKFRKFKLILKPSVDLLSNDLKSVNIDRFGRETPVPIDGSQFYQGFVSGAEKSSVSAFLGNDKMLSINIILDDDIFQVEPLSRYVQNNSSFI---VYRYSDLKGNFTRGPKCFAKNISSFE------------TNTTNSRQKRNVDAIISLPYINK-----DSTKKLCTIKLIADYRFHREHGRGEMGRTQHYLIELIDKINILFKSTDFVDSKNNKNSGYGFIINQILVHVEPTIGPSGHYNQEVAKQTDAWTVEGLLDSFGDIDHKDSCLAHLFTFQSFSEGTLGLAYMASSKTLSYGGICSERDFRHQNSKLVSVNTAWSTYRDAVGKRVISMSAYLVTAHELGHNWGADHDPDTTDCAP------NAARGGKYVMYTYSVVGYEPNNRLFSPCSRRSIGATIATRGEYCFLSPMNAFCGNSRVDDNEECDVGKNNS-ADACCTS-------DCHFKPGAVCSPNNHECCTNDCQFKPYGFVCAAKDPMNPCVNHSICSGKEKEC-LGPLSIDGPNC-TEHGRCSSGKCR-PYCEQLNMEACICDKIE------ESCLICCRDPPSKINSNTIQECRPAQNGIQSRLTLNQGRPC 1855
            ++F    R F L +K    L + DL    I+  G + P  +D S  Y G + G   + +   + + +     I  D   + VEP  RY+QN ++ +   +Y   D+      GP+    + S FE            ++   + +K + +     P I +     ++ K +C + +  D+ F + +G  E    Q  +   +  IN ++ +TDF+  K     G  F++ +I ++     G     ++    +     VE  L+   + +H D CLA++FT + F +G LGLA++ S+   S GGIC ++  ++ + K  S+NT   T ++  G  +    +++  AHE+GHN+G+ HD +  +C P      N  + G Y+MY  +  G + NN  FS CS  SI + ++ +   CF+ P  A CGN  V++ EECD G +    D CC S        C  KPG  CSP+   CC+N+C+FK     C  +   + C     C+G    C       D   C +E   C +G C    C +  +E CIC   +      E C +CC++       ++    R A+   ++ LT+  G PC
Sbjct:    5 LNFHAHGRHFPLRMKRDTTLFTPDLV---IEDSGDQPP--LDTSHIYSGEIFGERNTRIHGSVVDGRFEGF-INTDLGTYYVEPAERYLQNKNTTVHSVIYHEDDIDYPHKYGPEGGCAHDSVFERMKKHQMSAVEESDKEMNFEKEDEEEDTYGPVILRKKRAAENEKTVCQLFIQTDHLFLKYYGSREAVLAQ--ISNHVSAINAIYMNTDFMGIK-----GISFMVKRIRIN-----GTKEANDESNPFRFSNIGVETFLNLNSEQNHDDFCLAYVFTDRDFDDGVLGLAWVGSTAG-SSGGIC-QKTKKYGDGKYQSLNTGIITVQN-YGSHIPPTVSHITFAHEVGHNFGSHHDSEM-ECKPGESNDRNTKKLGNYIMYARATSGSKLNNNKFSQCSLHSINSVLSRKRNICFVEPGQASCGNGLVENGEECDCGYSEECKDPCCYSASEEISKRCKIKPGTECSPSGGPCCSNECKFKNSSNTCRLE---SDCALKGFCNGSSALCPKSKAKEDFTTCNSETQICQNGVCTGSICHKYKLEDCICSSEDIMNMPAELCHVCCQESLDPTTCSSTSSERWAKYFNKTVLTMPPGSPC 581          

Query:   80 NFVFGDWQNQLSDYDILPNLNIRISRSTFDNKKISFSTKFRKFKLILKPSVDLLSNDLKSVNIDRFGRETPVPIDGSQFYQGFVSGAEKSSVSAFLGNDKMLSINIILDDDIFQVEPLSRYVQNNSSFIVYRYSDLKGNFTRGPKCFAKNISSFETNTTNSRQKRNVDAIISLPYINKDSTKKLCTIKLIADYRFHREHGRGEMGRTQHYLIELIDKINILFKSTDFVDSKNNKNSGYGFIINQILVHVEPTIGPSGHYNQEVAKQTDAWTVEGLLDSFGDIDHKDSCLAHLFTFQSFSEGTLGLAYMASSKTLSYGGICSERDFRHQNSKLVSVNTAWSTYRDAVGKRVISMSAYLVTAHELGHNWGADHDPDTTDCAPNAARGGKYVMYTYSVVGYEPNNRLFSPCSRRSIGATIATRGEYCFLSPMNAFCGNSRVDDNEECDVGKNNSADACCTSDCHFKPGAVCSPNNHECCTNDCQFKPYGFVCAAKDPMNPCVNHSICSGKEKECLGPLSIDGPNCTEHGRCSSGKCRPYCEQLNMEACICDKIEESCLICCRDPPSKINSNTIQECRPAQNGIQSRLTLNQGRPCALGVCEEGVCKRRVNKLVERIWKIIDEFNTNLFAAFLLENXXXXXXXXXXXXXXPAAILVSCNDAKHRRRFLQERKSRRPEVFENFS 2116
            NFVFGDWQNQLSDYDILPNLNIRISRSTFDNKKISFSTKFRKFKLILKPSVDLLSNDLKSVNIDRFGRETPVPIDGSQFYQGFVSGAEKSSVSAFLGNDKMLSINIILDDDIFQVEPLSRYVQNNSSFIVYRYSDLKGNFTRGPKCFAKNISSFETNTTNSRQKRNVDAIISLPYINKDSTKKLCTIKLIADYRFHREHGRGEMGRTQHYLIELIDKINILFKSTDFVDSKNNKNSGYGFIINQILVHVEPTIGPSGHYNQEVAKQTDAWTVEGLLDSFGDIDHKDSCLAHLFTFQSFSEGTLGLAYMASSKTLSYGGICSERDFRHQNSKLVSVNTAWSTYRDAVGKRVISMSAYLVTAHELGHNWGADHDPDTTDCAPNAARGGKYVMYTYSVVGYEPNNRLFSPCSRRSIGATIATRGEYCFLSPMNAFCGNSRVDDNEECDVGKNNSAD CCTSDCHFKPGAVCSPNNHECCTNDCQFKPYGFVCAAKDPMNPCVNHSICSGKEKECLGPLSIDGPNCTEHGRCSSGKCRPYCEQ NMEACICDKIEESCLICCRDPPSKINSNTIQECRPAQNGIQSRLTLNQGRPCALGVCEEGVCKRRVNKLVERIWKIIDEFNTNLFAAFLLENLVGTVIILTLILWIPAAILVSCNDAKHRRRFLQERKSRRPEVFENFS
Sbjct:   17 NFVFGDWQNQLSDYDILPNLNIRISRSTFDNKKISFSTKFRKFKLILKPSVDLLSNDLKSVNIDRFGRETPVPIDGSQFYQGFVSGAEKSSVSAFLGNDKMLSINIILDDDIFQVEPLSRYVQNNSSFIVYRYSDLKGNFTRGPKCFAKNISSFETNTTNSRQKRNVDAIISLPYINKDSTKKLCTIKLIADYRFHREHGRGEMGRTQHYLIELIDKINILFKSTDFVDSKNNKNSGYGFIINQILVHVEPTIGPSGHYNQEVAKQTDAWTVEGLLDSFGDIDHKDSCLAHLFTFQSFSEGTLGLAYMASSKTLSYGGICSERDFRHQNSKLVSVNTAWSTYRDAVGKRVISMSAYLVTAHELGHNWGADHDPDTTDCAPNAARGGKYVMYTYSVVGYEPNNRLFSPCSRRSIGATIATRGEYCFLSPMNAFCGNSRVDDNEECDVGKNNSADTCCTSDCHFKPGAVCSPNNHECCTNDCQFKPYGFVCAAKDPMNPCVNHSICSGKEKECLGPLSIDGPNCTEHGRCSSGKCRPYCEQFNMEACICDKIEESCLICCRDPPSKINSNTIQECRPAQNGIQSRLTLNQGRPCALGVCEEGVCKRRVNKLVERIWKIIDEFNTNLFAAFLLENLVGTVIILTLILWIPAAILVSCNDAKHRRRFLQERKSRRPEVFENFS 695          

Query:  215 ILKPSVDLLSNDLKSVNIDRFGRETPVPIDG-------SQFYQGFVSGAEKSSVSAFLGNDKMLSINIILDDDIFQVEPLSRYVQNNSSF--IVYR-----------YSDLKG----NFTRGPKCFAKNISSFETNTTN----------SRQKRNVDAIISLPYINKDSTKKLCTIKLIADYRFHREHGRGEMGRTQHYL-IELIDKI--------NILFKSTDFVD-SKNNKNSGYGFIINQILVHVEPTIGPSGHYNQEVAKQTDAWTVEGLLDSFGDIDHKDSCLAHLFTFQSFSEGTLGLAYMASSKTLSYGGICSERDFRHQNSKLV--SVNTAWSTYRDAVGKRVISMSAYLVTAHELGHNWGADHDPD---TTDCAPNAAR-GGKYVMYTYSVVGYEPNNRLFSPCSRRSIGATI--ATRGE-YCFLSPMNAFCGNSRVDDNEECDVGKNNS--ADACCT-----SDCHFKPGAV---------CSPNNHECCTNDCQFKPYGFVCAAKDPMNPCVNHSICSGKEKECLGPLSI-DGPNCTEHGR-CSSGKC 1678
            +   + ++L ND KS +++ F     +P+ G       SQ Y   V G  +     F+ +DK           I+ VE  S Y +N+  F  I+Y            YSDLK      +T        +++S + N              RQKR+V         +    + +C + L +D     +       + Q YL I+ I  I          ++++T+F   + ++K +G GF ++++ ++      P G         +    V   L+    + H D CLA++FT++ F+ GTLGLA++A       GG+C +     + S+ V  S+NT   T  +  G  V    + L  AHE+GHN+G+ HD D     DC P      G Y+M+  +  G + NN  FS CSR SI   +   T+G   CFL    +FCGN   +D E+CD G ++    D CC      S C   P  +         CSP+  ECCTNDCQF+P   +C  K     C   + C+G   +C     + D   C ++ R C +G+C
Sbjct:   76 VFYKNTEILVND-KSHHLNDF-----IPVKGHLHNDFSSQVYGTIVDGVFR----GFIQSDKKNQ-----SSGIYYVEHSSYYFENDPGFHSIIYHDSHLHDSHNLNYSDLKNPSFCGWTNSNISHVMHLASVQHNKNKINDFTERPQPKRQKRSV---------SNKGNQYVCNLFLQSDTFLWDKIMSLHHIKGQKYLAIKEISSIFTQHVQGAQAIYQNTNFQKFNGDDKYNGIGFRVDRVRINTTDDCDP-GQIRDSNPFCSANIDVTNFLNLNSYVKHDDFCLAYIFTYRDFNGGTLGLAWVAEPG--GSGGVCEKHRMMQEGSQNVKKSLNTGIVTLLN-YGSYVALKVSQLTFAHEMGHNFGSKHDDDHKENQDCLPLVEDPKGNYIMFASATSGDKENNNKFSVCSRDSIARLLNRVTKGSGNCFLHQEGSFCGNKLAEDGEQCDCGYSSKDCQDKCCNPKMSNSPCKLTPKILINKQWKPVYCSPSAGECCTNDCQFQPVQHLCRTK---GECHKAAYCNGTHTKCPKSKKVPDLTKCQDNTRVCKNGQC 603          

Query: 1148 LVTAHELGHNWGADHDPDTTDCAPNAARGGKYVMYTYSVVGYEPNNRLFSPCSRRSIGATIA-TRGEYCFLS-PMNAFCGNSRVDDNEECDVGKNNSADACCTSDCHFKPGAVCSPNNH--ECCT-NDCQFKPYGFVCAAKDPMNPCVNHSICSGKEKECLGPLSIDGPN-CTEHG-RCSSGKCR-PYCEQLNMEACICDKIEES-CLICCRDPPSKINSNTIQECRPAQ 1810
            ++T HE+GH + A HD +TT CA N +    ++M  +    Y+ N   FS CS   +   I+  R ++CF +  +N++CGN  +++ EECD G       C T+ C  +  A CSP      CC  ++C++K      + K     C     C  K   C    ++ G   C ++  RC +G C    C   NME     +I ++ C + C D  SKI S+     R  Q
Sbjct:  303 IITTHEIGHTFNARHDDETT-CASNGS--FYFIMNAF----YKRNLPKFSNCSISEMSRYISFYREQHCFGNRILNSYCGNGILEEVEECDCGLRLRCLCCKTNICRLEANAECSPFGAFGMCCNESNCRWKSRSLNISCKFE-TECSMKGFCH-KNVGCQSDFNVPGKVLCAKNSKRCVAGVCSDSICSFWNMEEVKSYQISKTNCSLFCFDNTSKIMSSVSALPRLGQ 523          

Query: 1133 SMSAYLVTAHELGHNWGADHDPDTTDCAPNAARGGKYVMYTYSVVG-YEPNNRLFSPCSRRSIGATIATRGE-YCFLSPMNA-FCGNSRVDDNEECDVGKNNSADACCTSD-CHFKPGAVCSP--NNHECC-TNDCQFKPYG--FVCAAKDPMNPCVNHSICS 1594
            S S  L+ AHE+GH   A+HD  TT C  N +       + Y + G        FS CS   +   +   G  YCF S M   FCGN  ++ NEECD G+      CCT   C F   + CSP   N  CC    C++KP     +C+       CV  S C+
Sbjct:  315 SYSISLILAHEIGHLLNANHDEATT-CKTNGS-------FNYIMQGDLSTTIPKFSNCSIDDMLTYVKASGRSYCFFSIMRTEFCGNGILEKNEECDCGERQHDCPCCTGPICLFTKKSQCSPFGRNSMCCDIKTCKWKPRSDNIICSLN---TDCVPRSFCT 466          

Query: 1082 VNTAWSTYRDAVGKRVISMSAY--LVTAHELGHNWGADHDPDTTDCAPNAARGGKYVMYTYSVVGYEPNNRLFSPCSRRSIGA-TIATRGEYCFLSPM-NAFCGNSRVDDNEECDVGKNNSADACCTSD-CHFKPGAVCSPNNHE--CC-TNDCQFKP 1531
            +N     + + + K ++  S Y  L+ AHE+GH   A  D  TT C  N +    Y+M++     Y      FS CS  ++    +     YCF + + +AFCGN  ++D E+CD GK+     CC  D C F   A CSP + +  CC    C++KP
Sbjct:  267 LNNLRHFFLNLLSKSLMKSSYYTSLILAHEIGHLLNARDDEATT-CKTNGSFN--YIMHS----SYNKTIPKFSNCSIWNMSVYAMVNHYRYCFYNGLRSAFCGNGIIEDAEQCDCGKDQFYCPCCRRDYCIFTANAQCSPFSRDSMCCDIKTCRWKP 417