AP complex subunit sigma

Overview
NameAP complex subunit sigma
Smed IDSMED30008812
Length (bp)1019
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of AP complex subunit sigma (SMED30008812) t-SNE clustered cells

Violin plots show distribution of expression levels for AP complex subunit sigma (SMED30008812) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of AP complex subunit sigma (SMED30008812) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for AP complex subunit sigma (SMED30008812) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30008812

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 4

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
pharynxSMED30008812h1SMcG0018114 Contig2145GPL15192PMID:23079596
Forsthoefel et al., 2012		whole organism asexual adult colorimetric in situ hybridization evidence
gutSMED30008812h1SMcG0018114 Contig2145GPL15192PMID:23079596
Forsthoefel et al., 2012		whole organism asexual adult colorimetric in situ hybridization evidence
intestinal phagocyteSMED30008812h1SMcG0018114 Contig2145GPL15192PMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
neoblastSMED30008812h1SMcG0018114 dd_Smed_v4_5324_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of AP complex subunit sigma vs. Ensembl Human
Match: AP2S1 (adaptor related protein complex 2 subunit sigma 1 [Source:HGNC Symbol;Acc:HGNC:565])

HSP 1 Score: 262.692 bits (670), Expect = 2.960e-88
Identity = 126/142 (88.73%), Postives = 134/142 (94.37%), Query Frame = 1 
Query:   85 MIRFILIQNRAGKTRLAKWYMTFDDEEKQKLIEEVHALVTVRDAKHTNFVEFRTFKIVYRRYAGLYFCICVDVMDNSLMYLEAIHNFVEVLNELFHNVCELDLVFNFYRVYSVVDEMFLAGEIRETSQTKVLKQMAQLNSLD 510
            MIRFILIQNRAGKTRLAKWYM FDD+EKQKLIEEVHA+VTVRDAKHTNFVEFR FKI+YRRYAGLYFCICVDV DN+L YLEAIHNFVEVLNE FHNVCELDLVFNFY+VY+VVDEMFLAGEIRETSQTKVLKQ+  L SL+
Sbjct:    1 MIRFILIQNRAGKTRLAKWYMQFDDDEKQKLIEEVHAVVTVRDAKHTNFVEFRNFKIIYRRYAGLYFCICVDVNDNNLAYLEAIHNFVEVLNEYFHNVCELDLVFNFYKVYTVVDEMFLAGEIRETSQTKVLKQLLMLQSLE 142
[Close]
BLAST of AP complex subunit sigma vs. Ensembl Human
Match: AP2S1 (adaptor related protein complex 2 subunit sigma 1 [Source:HGNC Symbol;Acc:HGNC:565])

HSP 1 Score: 260.381 bits (664), Expect = 2.744e-87
Identity = 125/141 (88.65%), Postives = 133/141 (94.33%), Query Frame = 1 
Query:   88 IRFILIQNRAGKTRLAKWYMTFDDEEKQKLIEEVHALVTVRDAKHTNFVEFRTFKIVYRRYAGLYFCICVDVMDNSLMYLEAIHNFVEVLNELFHNVCELDLVFNFYRVYSVVDEMFLAGEIRETSQTKVLKQMAQLNSLD 510
            IRFILIQNRAGKTRLAKWYM FDD+EKQKLIEEVHA+VTVRDAKHTNFVEFR FKI+YRRYAGLYFCICVDV DN+L YLEAIHNFVEVLNE FHNVCELDLVFNFY+VY+VVDEMFLAGEIRETSQTKVLKQ+  L SL+
Sbjct:    4 IRFILIQNRAGKTRLAKWYMQFDDDEKQKLIEEVHAVVTVRDAKHTNFVEFRNFKIIYRRYAGLYFCICVDVNDNNLAYLEAIHNFVEVLNEYFHNVCELDLVFNFYKVYTVVDEMFLAGEIRETSQTKVLKQLLMLQSLE 144
[Close]
BLAST of AP complex subunit sigma vs. Ensembl Human
Match: AP2S1 (adaptor related protein complex 2 subunit sigma 1 [Source:HGNC Symbol;Acc:HGNC:565])

HSP 1 Score: 259.996 bits (663), Expect = 5.482e-87
Identity = 125/141 (88.65%), Postives = 133/141 (94.33%), Query Frame = 1 
Query:   88 IRFILIQNRAGKTRLAKWYMTFDDEEKQKLIEEVHALVTVRDAKHTNFVEFRTFKIVYRRYAGLYFCICVDVMDNSLMYLEAIHNFVEVLNELFHNVCELDLVFNFYRVYSVVDEMFLAGEIRETSQTKVLKQMAQLNSLD 510
            IRFILIQNRAGKTRLAKWYM FDD+EKQKLIEEVHA+VTVRDAKHTNFVEFR FKI+YRRYAGLYFCICVDV DN+L YLEAIHNFVEVLNE FHNVCELDLVFNFY+VY+VVDEMFLAGEIRETSQTKVLKQ+  L SL+
Sbjct:   18 IRFILIQNRAGKTRLAKWYMQFDDDEKQKLIEEVHAVVTVRDAKHTNFVEFRNFKIIYRRYAGLYFCICVDVNDNNLAYLEAIHNFVEVLNEYFHNVCELDLVFNFYKVYTVVDEMFLAGEIRETSQTKVLKQLLMLQSLE 158
[Close]
BLAST of AP complex subunit sigma vs. Ensembl Human
Match: AP2S1 (adaptor related protein complex 2 subunit sigma 1 [Source:HGNC Symbol;Acc:HGNC:565])

HSP 1 Score: 254.218 bits (648), Expect = 9.278e-85
Identity = 126/156 (80.77%), Postives = 134/156 (85.90%), Query Frame = 1 
Query:   85 MIRFILIQNRAGKTRLAKWYMTFDDEEKQKLIEEVHALVTVRDAKHTNFVE--------------FRTFKIVYRRYAGLYFCICVDVMDNSLMYLEAIHNFVEVLNELFHNVCELDLVFNFYRVYSVVDEMFLAGEIRETSQTKVLKQMAQLNSLD 510
            MIRFILIQNRAGKTRLAKWYM FDD+EKQKLIEEVHA+VTVRDAKHTNFVE              FR FKI+YRRYAGLYFCICVDV DN+L YLEAIHNFVEVLNE FHNVCELDLVFNFY+VY+VVDEMFLAGEIRETSQTKVLKQ+  L SL+
Sbjct:    1 MIRFILIQNRAGKTRLAKWYMQFDDDEKQKLIEEVHAVVTVRDAKHTNFVEVLAISVADSLSVLQFRNFKIIYRRYAGLYFCICVDVNDNNLAYLEAIHNFVEVLNEYFHNVCELDLVFNFYKVYTVVDEMFLAGEIRETSQTKVLKQLLMLQSLE 156
[Close]
BLAST of AP complex subunit sigma vs. Ensembl Human
Match: AP2S1 (adaptor related protein complex 2 subunit sigma 1 [Source:HGNC Symbol;Acc:HGNC:565])

HSP 1 Score: 219.55 bits (558), Expect = 1.317e-71
Identity = 106/122 (86.89%), Postives = 114/122 (93.44%), Query Frame = 1 
Query:  145 MTFDDEEKQKLIEEVHALVTVRDAKHTNFVEFRTFKIVYRRYAGLYFCICVDVMDNSLMYLEAIHNFVEVLNELFHNVCELDLVFNFYRVYSVVDEMFLAGEIRETSQTKVLKQMAQLNSLD 510
            M FDD+EKQKLIEEVHA+VTVRDAKHTNFVEFR FKI+YRRYAGLYFCICVDV DN+L YLEAIHNFVEVLNE FHNVCELDLVFNFY+VY+VVDEMFLAGEIRETSQTKVLKQ+  L SL+
Sbjct:    1 MQFDDDEKQKLIEEVHAVVTVRDAKHTNFVEFRNFKIIYRRYAGLYFCICVDVNDNNLAYLEAIHNFVEVLNEYFHNVCELDLVFNFYKVYTVVDEMFLAGEIRETSQTKVLKQLLMLQSLE 122
[Close]
BLAST of AP complex subunit sigma vs. Ensembl Celegans
Match: aps-2 (AP complex subunit sigma [Source:UniProtKB/TrEMBL;Acc:Q19123])

HSP 1 Score: 261.151 bits (666), Expect = 4.136e-88
Identity = 126/142 (88.73%), Postives = 133/142 (93.66%), Query Frame = 1 
Query:   85 MIRFILIQNRAGKTRLAKWYMTFDDEEKQKLIEEVHALVTVRDAKHTNFVEFRTFKIVYRRYAGLYFCICVDVMDNSLMYLEAIHNFVEVLNELFHNVCELDLVFNFYRVYSVVDEMFLAGEIRETSQTKVLKQMAQLNSLD 510
            MIRFILIQNRAGKTRLAKWYM FDD+EKQKLIEEVHA VTVRDAKHTNFVEFR FKIVYRRYAGLYFCICVD+ DN+L YLEAIHNFVEVLNE FHNVCELDLVFNFY+VY+VVDEMFLAGEIRETSQTKVLKQ+  L SL+
Sbjct:    1 MIRFILIQNRAGKTRLAKWYMHFDDDEKQKLIEEVHACVTVRDAKHTNFVEFRNFKIVYRRYAGLYFCICVDITDNNLYYLEAIHNFVEVLNEYFHNVCELDLVFNFYKVYTVVDEMFLAGEIRETSQTKVLKQLLMLTSLE 142
[Close]
BLAST of AP complex subunit sigma vs. Ensembl Celegans
Match: aps-1 (AP complex subunit sigma [Source:UniProtKB/TrEMBL;Acc:O16369])

HSP 1 Score: 140.584 bits (353), Expect = 8.325e-41
Identity = 62/136 (45.59%), Postives = 97/136 (71.32%), Query Frame = 1 
Query:   85 MIRFILIQNRAGKTRLAKWYMTFDDEEKQKLIEEVHALVTVRDAKHTNFVEFRTFKIVYRRYAGLYFCICVDVMDNSLMYLEAIHNFVEVLNELFHNVCELDLVFNFYRVYSVVDEMFLAGEIRETSQTKVLKQMA 492
            M++++L+ +R GK RL KWY  + D++K+K+  E+   +  R  K   F+E++  K+VY+RYA LYFC  ++  DN L+ LE IH +VE+L++ F +VCELD++FNF + Y ++DE  LAGEI+ETS+ +VLK +A
Sbjct:    1 MMQYMLLFSRQGKLRLQKWYTAYPDKQKKKICRELITQILARKPKMCAFLEYKDLKVVYKRYASLYFCCAIEQNDNELITLEVIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLLAGEIQETSKKQVLKAIA 136
[Close]
BLAST of AP complex subunit sigma vs. Ensembl Celegans
Match: aps-3 (AdaPtin, Small chain (Clathrin associated complex) [Source:UniProtKB/TrEMBL;Acc:Q8T874])

HSP 1 Score: 109.383 bits (272), Expect = 1.904e-28
Identity = 55/147 (37.41%), Postives = 92/147 (62.59%), Query Frame = 1 
Query:   85 MIRFILIQNRAGKTRLAKWYMTFDDEEKQKLIEEVHALVTVRDAKHTNFVEFRT------FKIVYRRYAGLYFCICVDVMDNSLMYLEAIHNFVEVLNELFHNVCELDLVFNFYRVYSVVDEMFLAGEIRETSQTKVLKQMAQLNSL 507
            MI+ IL+ N  GK RL K+Y  + +E++Q+++ E   LV+ RD    NF+E  T      ++++YR YA LYF  CVD  ++ L  L+ I  FVE L+  F NVCELDL+F+  RV+ ++ E+ + G + ET+  ++L+++ + + +
Sbjct:    1 MIKAILVINNHGKPRLLKFYQHYPEEKQQQIVRETFQLVSKRDDNVCNFLEGGTLIDGNDYRLIYRHYATLYFIFCVDSSESELGILDLIQVFVETLDRCFENVCELDLIFHVDRVHHILGEIVMGGMVLETNMNEILQRIQEQDKI 147
[Close]
BLAST of AP complex subunit sigma vs. Ensembl Fly
Match: AP-2sigma (gene:FBgn0043012 transcript:FBtr0084103)

HSP 1 Score: 266.159 bits (679), Expect = 5.999e-90
Identity = 129/142 (90.85%), Postives = 135/142 (95.07%), Query Frame = 1 
Query:   85 MIRFILIQNRAGKTRLAKWYMTFDDEEKQKLIEEVHALVTVRDAKHTNFVEFRTFKIVYRRYAGLYFCICVDVMDNSLMYLEAIHNFVEVLNELFHNVCELDLVFNFYRVYSVVDEMFLAGEIRETSQTKVLKQMAQLNSLD 510
            MIRFILIQNRAGKTRLAKWYM FDD+EKQKLIEEVHA+VTVRDAKHTNFVEFR FKIVYRRYAGLYFCICVDV DN+L YLEAIHNFVEVLNE FHNVCELDLVFNFY+VYSVVDEMFLAGEIRETSQTKVLKQ+  LNSL+
Sbjct:    1 MIRFILIQNRAGKTRLAKWYMNFDDDEKQKLIEEVHAVVTVRDAKHTNFVEFRNFKIVYRRYAGLYFCICVDVNDNNLCYLEAIHNFVEVLNEYFHNVCELDLVFNFYKVYSVVDEMFLAGEIRETSQTKVLKQLLTLNSLE 142
[Close]
BLAST of AP complex subunit sigma vs. Ensembl Fly
Match: AP-1sigma (gene:FBgn0039132 transcript:FBtr0335244)

HSP 1 Score: 139.813 bits (351), Expect = 2.090e-40
Identity = 64/141 (45.39%), Postives = 98/141 (69.50%), Query Frame = 1 
Query:   85 MIRFILIQNRAGKTRLAKWYMTFDDEEKQKLIEEVHALVTVRDAKHTNFVEFRTFKIVYRRYAGLYFCICVDVMDNSLMYLEAIHNFVEVLNELFHNVCELDLVFNFYRVYSVVDEMFLAGEIRETSQTKVLKQMAQLNSL 507
            M+ F+L+ +R GK RL KWYM + D+ K+K+  E+   +  R  K  +F+E++  KIVY+RYA LYFC  ++  DN L+ LE IH +VE+L++ F +VCELD++FNF + Y ++DE+ + GEI+ETS+  VLK +A  + L
Sbjct:    1 MMLFMLLFSRQGKLRLQKWYMAYPDKVKKKITRELVTTILARKPKMCSFLEWKDCKIVYKRYASLYFCCAIEQNDNELLTLEIIHRYVELLDKYFGSVCELDIIFNFEKAYFILDELLIGGEIQETSKKNVLKAIASQDLL 141
[Close]
BLAST of AP complex subunit sigma vs. Ensembl Fly
Match: AP-1sigma (gene:FBgn0039132 transcript:FBtr0305039)

HSP 1 Score: 139.813 bits (351), Expect = 2.206e-40
Identity = 64/141 (45.39%), Postives = 98/141 (69.50%), Query Frame = 1 
Query:   85 MIRFILIQNRAGKTRLAKWYMTFDDEEKQKLIEEVHALVTVRDAKHTNFVEFRTFKIVYRRYAGLYFCICVDVMDNSLMYLEAIHNFVEVLNELFHNVCELDLVFNFYRVYSVVDEMFLAGEIRETSQTKVLKQMAQLNSL 507
            M+ F+L+ +R GK RL KWYM + D+ K+K+  E+   +  R  K  +F+E++  KIVY+RYA LYFC  ++  DN L+ LE IH +VE+L++ F +VCELD++FNF + Y ++DE+ + GEI+ETS+  VLK +A  + L
Sbjct:    1 MMLFMLLFSRQGKLRLQKWYMAYPDKVKKKITRELVTTILARKPKMCSFLEWKDCKIVYKRYASLYFCCAIEQNDNELLTLEIIHRYVELLDKYFGSVCELDIIFNFEKAYFILDELLIGGEIQETSKKNVLKAIASQDLL 141
[Close]
BLAST of AP complex subunit sigma vs. Ensembl Fly
Match: AP-1sigma (gene:FBgn0039132 transcript:FBtr0305040)

HSP 1 Score: 139.813 bits (351), Expect = 2.206e-40
Identity = 64/141 (45.39%), Postives = 98/141 (69.50%), Query Frame = 1 
Query:   85 MIRFILIQNRAGKTRLAKWYMTFDDEEKQKLIEEVHALVTVRDAKHTNFVEFRTFKIVYRRYAGLYFCICVDVMDNSLMYLEAIHNFVEVLNELFHNVCELDLVFNFYRVYSVVDEMFLAGEIRETSQTKVLKQMAQLNSL 507
            M+ F+L+ +R GK RL KWYM + D+ K+K+  E+   +  R  K  +F+E++  KIVY+RYA LYFC  ++  DN L+ LE IH +VE+L++ F +VCELD++FNF + Y ++DE+ + GEI+ETS+  VLK +A  + L
Sbjct:    1 MMLFMLLFSRQGKLRLQKWYMAYPDKVKKKITRELVTTILARKPKMCSFLEWKDCKIVYKRYASLYFCCAIEQNDNELLTLEIIHRYVELLDKYFGSVCELDIIFNFEKAYFILDELLIGGEIQETSKKNVLKAIASQDLL 141
[Close]
BLAST of AP complex subunit sigma vs. Ensembl Fly
Match: AP-1sigma (gene:FBgn0039132 transcript:FBtr0084496)

HSP 1 Score: 139.813 bits (351), Expect = 2.352e-40
Identity = 64/141 (45.39%), Postives = 98/141 (69.50%), Query Frame = 1 
Query:   85 MIRFILIQNRAGKTRLAKWYMTFDDEEKQKLIEEVHALVTVRDAKHTNFVEFRTFKIVYRRYAGLYFCICVDVMDNSLMYLEAIHNFVEVLNELFHNVCELDLVFNFYRVYSVVDEMFLAGEIRETSQTKVLKQMAQLNSL 507
            M+ F+L+ +R GK RL KWYM + D+ K+K+  E+   +  R  K  +F+E++  KIVY+RYA LYFC  ++  DN L+ LE IH +VE+L++ F +VCELD++FNF + Y ++DE+ + GEI+ETS+  VLK +A  + L
Sbjct:    1 MMLFMLLFSRQGKLRLQKWYMAYPDKVKKKITRELVTTILARKPKMCSFLEWKDCKIVYKRYASLYFCCAIEQNDNELLTLEIIHRYVELLDKYFGSVCELDIIFNFEKAYFILDELLIGGEIQETSKKNVLKAIASQDLL 141
[Close]
BLAST of AP complex subunit sigma vs. Ensembl Zebrafish
Match: ap2s1 (adaptor related protein complex 2 subunit sigma 1 [Source:ZFIN;Acc:ZDB-GENE-040426-2174])

HSP 1 Score: 263.462 bits (672), Expect = 1.045e-88
Identity = 126/142 (88.73%), Postives = 134/142 (94.37%), Query Frame = 1 
Query:   85 MIRFILIQNRAGKTRLAKWYMTFDDEEKQKLIEEVHALVTVRDAKHTNFVEFRTFKIVYRRYAGLYFCICVDVMDNSLMYLEAIHNFVEVLNELFHNVCELDLVFNFYRVYSVVDEMFLAGEIRETSQTKVLKQMAQLNSLD 510
            MIRFILIQNRAGKTRLAKWYM FDD+EKQKLIEEVHA+VTVRDAKHTNFVEFR FKI+YRRYAGLYFCICVDV DN+L YLEAIHNFVEVLNE FHNVCELDLVFNFY+VY+VVDEMFLAGEIRETSQTKVLKQ+  L SL+
Sbjct:    1 MIRFILIQNRAGKTRLAKWYMQFDDDEKQKLIEEVHAVVTVRDAKHTNFVEFRNFKIIYRRYAGLYFCICVDVTDNNLAYLEAIHNFVEVLNEYFHNVCELDLVFNFYKVYTVVDEMFLAGEIRETSQTKVLKQLLMLQSLE 142
[Close]
BLAST of AP complex subunit sigma vs. Ensembl Zebrafish
Match: ap1s1 (adaptor related protein complex 1 subunit sigma 1 [Source:ZFIN;Acc:ZDB-GENE-040426-1119])

HSP 1 Score: 143.665 bits (361), Expect = 8.617e-42
Identity = 66/141 (46.81%), Postives = 98/141 (69.50%), Query Frame = 1 
Query:   85 MIRFILIQNRAGKTRLAKWYMTFDDEEKQKLIEEVHALVTVRDAKHTNFVEFRTFKIVYRRYAGLYFCICVDVMDNSLMYLEAIHNFVEVLNELFHNVCELDLVFNFYRVYSVVDEMFLAGEIRETSQTKVLKQMAQLNSL 507
            M+RF+L+ +R GK RL KWY    + +K+K++ E+  +V  R  K  +F+E+R  KIVY+RYA LYFC  V+  DN L+ LE IH FVE+L++ F +VCELD++FNF + Y ++DE  + GEI++TS+  VLK + Q + L
Sbjct:    1 MMRFMLLFSRQGKLRLQKWYTATAERDKKKMVRELMQVVLARKPKMCSFLEWRDLKIVYKRYASLYFCCAVEEQDNELITLEVIHRFVELLDKYFGSVCELDIIFNFEKAYFILDEFLMGGEIQDTSKKSVLKAIEQADLL 141
[Close]
BLAST of AP complex subunit sigma vs. Ensembl Zebrafish
Match: ap1s1 (adaptor related protein complex 1 subunit sigma 1 [Source:ZFIN;Acc:ZDB-GENE-040426-1119])

HSP 1 Score: 142.124 bits (357), Expect = 4.523e-41
Identity = 65/140 (46.43%), Postives = 97/140 (69.29%), Query Frame = 1 
Query:   88 IRFILIQNRAGKTRLAKWYMTFDDEEKQKLIEEVHALVTVRDAKHTNFVEFRTFKIVYRRYAGLYFCICVDVMDNSLMYLEAIHNFVEVLNELFHNVCELDLVFNFYRVYSVVDEMFLAGEIRETSQTKVLKQMAQLNSL 507
            +RF+L+ +R GK RL KWY    + +K+K++ E+  +V  R  K  +F+E+R  KIVY+RYA LYFC  V+  DN L+ LE IH FVE+L++ F +VCELD++FNF + Y ++DE  + GEI++TS+  VLK + Q + L
Sbjct:    1 MRFMLLFSRQGKLRLQKWYTATAERDKKKMVRELMQVVLARKPKMCSFLEWRDLKIVYKRYASLYFCCAVEEQDNELITLEVIHRFVELLDKYFGSVCELDIIFNFEKAYFILDEFLMGGEIQDTSKKSVLKAIEQADLL 140
[Close]
BLAST of AP complex subunit sigma vs. Ensembl Zebrafish
Match: ap1s1 (adaptor related protein complex 1 subunit sigma 1 [Source:ZFIN;Acc:ZDB-GENE-040426-1119])

HSP 1 Score: 142.124 bits (357), Expect = 4.523e-41
Identity = 65/140 (46.43%), Postives = 97/140 (69.29%), Query Frame = 1 
Query:   88 IRFILIQNRAGKTRLAKWYMTFDDEEKQKLIEEVHALVTVRDAKHTNFVEFRTFKIVYRRYAGLYFCICVDVMDNSLMYLEAIHNFVEVLNELFHNVCELDLVFNFYRVYSVVDEMFLAGEIRETSQTKVLKQMAQLNSL 507
            +RF+L+ +R GK RL KWY    + +K+K++ E+  +V  R  K  +F+E+R  KIVY+RYA LYFC  V+  DN L+ LE IH FVE+L++ F +VCELD++FNF + Y ++DE  + GEI++TS+  VLK + Q + L
Sbjct:    1 MRFMLLFSRQGKLRLQKWYTATAERDKKKMVRELMQVVLARKPKMCSFLEWRDLKIVYKRYASLYFCCAVEEQDNELITLEVIHRFVELLDKYFGSVCELDIIFNFEKAYFILDEFLMGGEIQDTSKKSVLKAIEQADLL 140
[Close]
BLAST of AP complex subunit sigma vs. Ensembl Zebrafish
Match: ap1s3a (adaptor related protein complex 1 subunit sigma 3a [Source:ZFIN;Acc:ZDB-GENE-050417-222])

HSP 1 Score: 141.354 bits (355), Expect = 6.266e-41
Identity = 63/141 (44.68%), Postives = 96/141 (68.09%), Query Frame = 1 
Query:   85 MIRFILIQNRAGKTRLAKWYMTFDDEEKQKLIEEVHALVTVRDAKHTNFVEFRTFKIVYRRYAGLYFCICVDVMDNSLMYLEAIHNFVEVLNELFHNVCELDLVFNFYRVYSVVDEMFLAGEIRETSQTKVLKQMAQLNSL 507
            M+RF+L+ +R GK RL KW+    D +K+K+I ++  +V  R  K  NF+ +R  KIVYRRYA LYFC  ++  DN L+ L+ +H +VE+L++ F NVCELD++FNF + Y ++DE  + GE++ETS+  V K + +  SL
Sbjct:    1 MMRFLLLFSRQGKLRLQKWFTVLSDRDKRKIIRDLTQMVLSRPPKACNFLPWRDLKIVYRRYASLYFCCGLEQDDNELLTLDILHRYVELLDQYFGNVCELDIIFNFEKAYFILDEFVIGGEVQETSKASVAKSIEEAESL 141
[Close]
BLAST of AP complex subunit sigma vs. Ensembl Xenopus
Match: ap2s1 (adaptor related protein complex 2 subunit sigma 1 [Source:NCBI gene;Acc:549079])

HSP 1 Score: 263.462 bits (672), Expect = 1.489e-88
Identity = 126/142 (88.73%), Postives = 134/142 (94.37%), Query Frame = 1 
Query:   85 MIRFILIQNRAGKTRLAKWYMTFDDEEKQKLIEEVHALVTVRDAKHTNFVEFRTFKIVYRRYAGLYFCICVDVMDNSLMYLEAIHNFVEVLNELFHNVCELDLVFNFYRVYSVVDEMFLAGEIRETSQTKVLKQMAQLNSLD 510
            MIRFILIQNRAGKTRLAKWYM FDD+EKQKLIEEVHA+VTVRDAKHTNFVEFR FKI+YRRYAGLYFCICVDV DN+L YLEAIHNFVEVLNE FHNVCELDLVFNFY+VY+VVDEMFLAGEIRETSQTKVLKQ+  L SL+
Sbjct:    1 MIRFILIQNRAGKTRLAKWYMQFDDDEKQKLIEEVHAVVTVRDAKHTNFVEFRNFKIIYRRYAGLYFCICVDVTDNNLAYLEAIHNFVEVLNEYFHNVCELDLVFNFYKVYTVVDEMFLAGEIRETSQTKVLKQLLMLQSLE 142
[Close]
BLAST of AP complex subunit sigma vs. Ensembl Xenopus
Match: ap2s1 (adaptor related protein complex 2 subunit sigma 1 [Source:NCBI gene;Acc:549079])

HSP 1 Score: 261.151 bits (666), Expect = 1.881e-87
Identity = 125/141 (88.65%), Postives = 133/141 (94.33%), Query Frame = 1 
Query:   88 IRFILIQNRAGKTRLAKWYMTFDDEEKQKLIEEVHALVTVRDAKHTNFVEFRTFKIVYRRYAGLYFCICVDVMDNSLMYLEAIHNFVEVLNELFHNVCELDLVFNFYRVYSVVDEMFLAGEIRETSQTKVLKQMAQLNSLD 510
            IRFILIQNRAGKTRLAKWYM FDD+EKQKLIEEVHA+VTVRDAKHTNFVEFR FKI+YRRYAGLYFCICVDV DN+L YLEAIHNFVEVLNE FHNVCELDLVFNFY+VY+VVDEMFLAGEIRETSQTKVLKQ+  L SL+
Sbjct:   17 IRFILIQNRAGKTRLAKWYMQFDDDEKQKLIEEVHAVVTVRDAKHTNFVEFRNFKIIYRRYAGLYFCICVDVTDNNLAYLEAIHNFVEVLNEYFHNVCELDLVFNFYKVYTVVDEMFLAGEIRETSQTKVLKQLLMLQSLE 157
[Close]
BLAST of AP complex subunit sigma vs. Ensembl Xenopus
Match: ap1s3 (adaptor related protein complex 1 subunit sigma 3 [Source:NCBI gene;Acc:549333])

HSP 1 Score: 142.895 bits (359), Expect = 2.877e-41
Identity = 63/133 (47.37%), Postives = 97/133 (72.93%), Query Frame = 1 
Query:   85 MIRFILIQNRAGKTRLAKWYMTFDDEEKQKLIEEVHALVTVRDAKHTNFVEFRTFKIVYRRYAGLYFCICVDVMDNSLMYLEAIHNFVEVLNELFHNVCELDLVFNFYRVYSVVDEMFLAGEIRETSQTKVLK 483
            MIRF+L+ +R GK RL KWY+T  D+EK K+  E+  ++  R+ K ++FV+++  K+VY+RYA LYFC  ++  DN L+ LE +H FVE+L++ F NVCELD++FNF + Y ++DE  + GEI+ETS+  V++
Sbjct:    1 MIRFLLLFSRQGKLRLQKWYVTLPDKEKHKISRELVHIILSRNPKMSSFVDWKDLKLVYKRYASLYFCCAIEDQDNELLALELVHRFVELLDKYFGNVCELDIIFNFEKAYFLLDEFLMGGEIQETSKDSVVR 133
[Close]
BLAST of AP complex subunit sigma vs. Ensembl Xenopus
Match: tbkbp1 (TBK1 binding protein 1 [Source:Xenbase;Acc:XB-GENE-962068])

HSP 1 Score: 141.739 bits (356), Expect = 8.424e-41
Identity = 65/140 (46.43%), Postives = 97/140 (69.29%), Query Frame = 1 
Query:   88 IRFILIQNRAGKTRLAKWYMTFDDEEKQKLIEEVHALVTVRDAKHTNFVEFRTFKIVYRRYAGLYFCICVDVMDNSLMYLEAIHNFVEVLNELFHNVCELDLVFNFYRVYSVVDEMFLAGEIRETSQTKVLKQMAQLNSL 507
            ++F+L+ +R GK RL KWY+   D+EK+K+  E+   V  R  K  +F+E+R  KIVY+RYA LYFC  ++  DN L+ LE IH +VE+L++ F +VCELD++FNF + Y ++DE  L GE++ETS+  VLK + Q + L
Sbjct:    7 MQFMLLFSRQGKLRLQKWYVPLSDKEKKKITRELVQTVLARKPKMCSFLEWRDLKIVYKRYASLYFCCAIEDQDNELITLEIIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLLGGEVQETSKKNVLKAIEQADLL 146
[Close]
BLAST of AP complex subunit sigma vs. Ensembl Xenopus
Match: plekha3 (pleckstrin homology domain containing A3 [Source:Xenbase;Acc:XB-GENE-961095])

HSP 1 Score: 140.584 bits (353), Expect = 2.448e-40
Identity = 63/140 (45.00%), Postives = 98/140 (70.00%), Query Frame = 1 
Query:   88 IRFILIQNRAGKTRLAKWYMTFDDEEKQKLIEEVHALVTVRDAKHTNFVEFRTFKIVYRRYAGLYFCICVDVMDNSLMYLEAIHNFVEVLNELFHNVCELDLVFNFYRVYSVVDEMFLAGEIRETSQTKVLKQMAQLNSL 507
            +RF+L+ +R GK RL KWY+   + +K+KL+ ++   V  R  K  +F+E++ FK+VY+RYA LYFC  V+  DN L+ LE IH +VE+L++ F +VCELD++FNF + Y ++DE  + GEI++TS+  VLK + Q + L
Sbjct:    1 MRFMLLFSRQGKLRLQKWYVAISERDKKKLVRDLMQTVLSRKPKMCSFLEWKDFKVVYKRYASLYFCCAVEDQDNELLTLELIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLMGGEIQDTSKKSVLKAIEQSDML 140
[Close]
BLAST of AP complex subunit sigma vs. Ensembl Mouse
Match: Ap2s1 (adaptor-related protein complex 2, sigma 1 subunit [Source:MGI Symbol;Acc:MGI:2141861])

HSP 1 Score: 262.692 bits (670), Expect = 2.032e-88
Identity = 126/142 (88.73%), Postives = 134/142 (94.37%), Query Frame = 1 
Query:   85 MIRFILIQNRAGKTRLAKWYMTFDDEEKQKLIEEVHALVTVRDAKHTNFVEFRTFKIVYRRYAGLYFCICVDVMDNSLMYLEAIHNFVEVLNELFHNVCELDLVFNFYRVYSVVDEMFLAGEIRETSQTKVLKQMAQLNSLD 510
            MIRFILIQNRAGKTRLAKWYM FDD+EKQKLIEEVHA+VTVRDAKHTNFVEFR FKI+YRRYAGLYFCICVDV DN+L YLEAIHNFVEVLNE FHNVCELDLVFNFY+VY+VVDEMFLAGEIRETSQTKVLKQ+  L SL+
Sbjct:    1 MIRFILIQNRAGKTRLAKWYMQFDDDEKQKLIEEVHAVVTVRDAKHTNFVEFRNFKIIYRRYAGLYFCICVDVNDNNLAYLEAIHNFVEVLNEYFHNVCELDLVFNFYKVYTVVDEMFLAGEIRETSQTKVLKQLLMLQSLE 142
[Close]
BLAST of AP complex subunit sigma vs. Ensembl Mouse
Match: Ap2s1 (adaptor-related protein complex 2, sigma 1 subunit [Source:MGI Symbol;Acc:MGI:2141861])

HSP 1 Score: 163.31 bits (412), Expect = 3.953e-50
Identity = 78/91 (85.71%), Postives = 84/91 (92.31%), Query Frame = 1 
Query:  238 FRTFKIVYRRYAGLYFCICVDVMDNSLMYLEAIHNFVEVLNELFHNVCELDLVFNFYRVYSVVDEMFLAGEIRETSQTKVLKQMAQLNSLD 510
            FR FKI+YRRYAGLYFCICVDV DN+L YLEAIHNFVEVLNE FHNVCELDLVFNFY+VY+VVDEMFLAGEIRETSQTKVLKQ+  L SL+
Sbjct:    2 FRNFKIIYRRYAGLYFCICVDVNDNNLAYLEAIHNFVEVLNEYFHNVCELDLVFNFYKVYTVVDEMFLAGEIRETSQTKVLKQLLMLQSLE 92
[Close]
BLAST of AP complex subunit sigma vs. Ensembl Mouse
Match: Ap1s1 (adaptor protein complex AP-1, sigma 1 [Source:MGI Symbol;Acc:MGI:1098244])

HSP 1 Score: 143.28 bits (360), Expect = 1.272e-41
Identity = 62/141 (43.97%), Postives = 100/141 (70.92%), Query Frame = 1 
Query:   85 MIRFILIQNRAGKTRLAKWYMTFDDEEKQKLIEEVHALVTVRDAKHTNFVEFRTFKIVYRRYAGLYFCICVDVMDNSLMYLEAIHNFVEVLNELFHNVCELDLVFNFYRVYSVVDEMFLAGEIRETSQTKVLKQMAQLNSL 507
            M+RF+L+ +R GK RL KWY+   D+E++K++ E+  +V  R  K  +F+E+R  K+VY+RYA LYFC  ++  DN L+ LE IH +VE+L++ F +VCELD++FNF + Y ++DE  + G++++TS+  VLK + Q + L
Sbjct:    1 MMRFMLLFSRQGKLRLQKWYLATSDKERKKMVRELMQVVLARKPKMCSFLEWRDLKVVYKRYASLYFCCAIEGQDNELITLELIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLMGGDVQDTSKKSVLKAIEQADLL 141
[Close]
BLAST of AP complex subunit sigma vs. Ensembl Mouse
Match: Ap1s1 (adaptor protein complex AP-1, sigma 1 [Source:MGI Symbol;Acc:MGI:1098244])

HSP 1 Score: 143.28 bits (360), Expect = 1.309e-41
Identity = 62/141 (43.97%), Postives = 100/141 (70.92%), Query Frame = 1 
Query:   85 MIRFILIQNRAGKTRLAKWYMTFDDEEKQKLIEEVHALVTVRDAKHTNFVEFRTFKIVYRRYAGLYFCICVDVMDNSLMYLEAIHNFVEVLNELFHNVCELDLVFNFYRVYSVVDEMFLAGEIRETSQTKVLKQMAQLNSL 507
            M+RF+L+ +R GK RL KWY+   D+E++K++ E+  +V  R  K  +F+E+R  K+VY+RYA LYFC  ++  DN L+ LE IH +VE+L++ F +VCELD++FNF + Y ++DE  + G++++TS+  VLK + Q + L
Sbjct:    1 MMRFMLLFSRQGKLRLQKWYLATSDKERKKMVRELMQVVLARKPKMCSFLEWRDLKVVYKRYASLYFCCAIEGQDNELITLELIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLMGGDVQDTSKKSVLKAIEQADLL 141
[Close]
BLAST of AP complex subunit sigma vs. Ensembl Mouse
Match: Ap1s2 (adaptor-related protein complex 1, sigma 2 subunit [Source:MGI Symbol;Acc:MGI:1889383])

HSP 1 Score: 141.739 bits (356), Expect = 5.204e-41
Identity = 65/140 (46.43%), Postives = 97/140 (69.29%), Query Frame = 1 
Query:   88 IRFILIQNRAGKTRLAKWYMTFDDEEKQKLIEEVHALVTVRDAKHTNFVEFRTFKIVYRRYAGLYFCICVDVMDNSLMYLEAIHNFVEVLNELFHNVCELDLVFNFYRVYSVVDEMFLAGEIRETSQTKVLKQMAQLNSL 507
            ++F+L+ +R GK RL KWY+   D+EK+K+  E+   V  R  K  +F+E+R  KIVY+RYA LYFC  ++  DN L+ LE IH +VE+L++ F +VCELD++FNF + Y ++DE  L GE++ETS+  VLK + Q + L
Sbjct:    1 MQFMLLFSRQGKLRLQKWYVPLSDKEKKKITRELVQTVLARKPKMCSFLEWRDLKIVYKRYASLYFCCAIEDQDNELITLEIIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLLGGEVQETSKKNVLKAIEQADLL 140
[Close]
BLAST of AP complex subunit sigma vs. UniProt/SwissProt
Match: sp|P62744|AP2S1_RAT (AP-2 complex subunit sigma OS=Rattus norvegicus OX=10116 GN=Ap2s1 PE=1 SV=1)

HSP 1 Score: 262.692 bits (670), Expect = 1.422e-87
Identity = 126/142 (88.73%), Postives = 134/142 (94.37%), Query Frame = 1 
Query:   85 MIRFILIQNRAGKTRLAKWYMTFDDEEKQKLIEEVHALVTVRDAKHTNFVEFRTFKIVYRRYAGLYFCICVDVMDNSLMYLEAIHNFVEVLNELFHNVCELDLVFNFYRVYSVVDEMFLAGEIRETSQTKVLKQMAQLNSLD 510
            MIRFILIQNRAGKTRLAKWYM FDD+EKQKLIEEVHA+VTVRDAKHTNFVEFR FKI+YRRYAGLYFCICVDV DN+L YLEAIHNFVEVLNE FHNVCELDLVFNFY+VY+VVDEMFLAGEIRETSQTKVLKQ+  L SL+
Sbjct:    1 MIRFILIQNRAGKTRLAKWYMQFDDDEKQKLIEEVHAVVTVRDAKHTNFVEFRNFKIIYRRYAGLYFCICVDVNDNNLAYLEAIHNFVEVLNEYFHNVCELDLVFNFYKVYTVVDEMFLAGEIRETSQTKVLKQLLMLQSLE 142
[Close]
BLAST of AP complex subunit sigma vs. UniProt/SwissProt
Match: sp|Q5R940|AP2S1_PONAB (AP-2 complex subunit sigma OS=Pongo abelii OX=9601 GN=AP2S1 PE=2 SV=1)

HSP 1 Score: 262.692 bits (670), Expect = 1.422e-87
Identity = 126/142 (88.73%), Postives = 134/142 (94.37%), Query Frame = 1 
Query:   85 MIRFILIQNRAGKTRLAKWYMTFDDEEKQKLIEEVHALVTVRDAKHTNFVEFRTFKIVYRRYAGLYFCICVDVMDNSLMYLEAIHNFVEVLNELFHNVCELDLVFNFYRVYSVVDEMFLAGEIRETSQTKVLKQMAQLNSLD 510
            MIRFILIQNRAGKTRLAKWYM FDD+EKQKLIEEVHA+VTVRDAKHTNFVEFR FKI+YRRYAGLYFCICVDV DN+L YLEAIHNFVEVLNE FHNVCELDLVFNFY+VY+VVDEMFLAGEIRETSQTKVLKQ+  L SL+
Sbjct:    1 MIRFILIQNRAGKTRLAKWYMQFDDDEKQKLIEEVHAVVTVRDAKHTNFVEFRNFKIIYRRYAGLYFCICVDVNDNNLAYLEAIHNFVEVLNEYFHNVCELDLVFNFYKVYTVVDEMFLAGEIRETSQTKVLKQLLMLQSLE 142
[Close]
BLAST of AP complex subunit sigma vs. UniProt/SwissProt
Match: sp|P62743|AP2S1_MOUSE (AP-2 complex subunit sigma OS=Mus musculus OX=10090 GN=Ap2s1 PE=1 SV=1)

HSP 1 Score: 262.692 bits (670), Expect = 1.422e-87
Identity = 126/142 (88.73%), Postives = 134/142 (94.37%), Query Frame = 1 
Query:   85 MIRFILIQNRAGKTRLAKWYMTFDDEEKQKLIEEVHALVTVRDAKHTNFVEFRTFKIVYRRYAGLYFCICVDVMDNSLMYLEAIHNFVEVLNELFHNVCELDLVFNFYRVYSVVDEMFLAGEIRETSQTKVLKQMAQLNSLD 510
            MIRFILIQNRAGKTRLAKWYM FDD+EKQKLIEEVHA+VTVRDAKHTNFVEFR FKI+YRRYAGLYFCICVDV DN+L YLEAIHNFVEVLNE FHNVCELDLVFNFY+VY+VVDEMFLAGEIRETSQTKVLKQ+  L SL+
Sbjct:    1 MIRFILIQNRAGKTRLAKWYMQFDDDEKQKLIEEVHAVVTVRDAKHTNFVEFRNFKIIYRRYAGLYFCICVDVNDNNLAYLEAIHNFVEVLNEYFHNVCELDLVFNFYKVYTVVDEMFLAGEIRETSQTKVLKQLLMLQSLE 142
[Close]
BLAST of AP complex subunit sigma vs. UniProt/SwissProt
Match: sp|P53680|AP2S1_HUMAN (AP-2 complex subunit sigma OS=Homo sapiens OX=9606 GN=AP2S1 PE=1 SV=2)

HSP 1 Score: 262.692 bits (670), Expect = 1.422e-87
Identity = 126/142 (88.73%), Postives = 134/142 (94.37%), Query Frame = 1 
Query:   85 MIRFILIQNRAGKTRLAKWYMTFDDEEKQKLIEEVHALVTVRDAKHTNFVEFRTFKIVYRRYAGLYFCICVDVMDNSLMYLEAIHNFVEVLNELFHNVCELDLVFNFYRVYSVVDEMFLAGEIRETSQTKVLKQMAQLNSLD 510
            MIRFILIQNRAGKTRLAKWYM FDD+EKQKLIEEVHA+VTVRDAKHTNFVEFR FKI+YRRYAGLYFCICVDV DN+L YLEAIHNFVEVLNE FHNVCELDLVFNFY+VY+VVDEMFLAGEIRETSQTKVLKQ+  L SL+
Sbjct:    1 MIRFILIQNRAGKTRLAKWYMQFDDDEKQKLIEEVHAVVTVRDAKHTNFVEFRNFKIIYRRYAGLYFCICVDVNDNNLAYLEAIHNFVEVLNEYFHNVCELDLVFNFYKVYTVVDEMFLAGEIRETSQTKVLKQLLMLQSLE 142
[Close]
BLAST of AP complex subunit sigma vs. UniProt/SwissProt
Match: sp|Q17QC5|AP2S1_BOVIN (AP-2 complex subunit sigma OS=Bos taurus OX=9913 GN=AP2S1 PE=2 SV=1)

HSP 1 Score: 262.692 bits (670), Expect = 1.422e-87
Identity = 126/142 (88.73%), Postives = 134/142 (94.37%), Query Frame = 1 
Query:   85 MIRFILIQNRAGKTRLAKWYMTFDDEEKQKLIEEVHALVTVRDAKHTNFVEFRTFKIVYRRYAGLYFCICVDVMDNSLMYLEAIHNFVEVLNELFHNVCELDLVFNFYRVYSVVDEMFLAGEIRETSQTKVLKQMAQLNSLD 510
            MIRFILIQNRAGKTRLAKWYM FDD+EKQKLIEEVHA+VTVRDAKHTNFVEFR FKI+YRRYAGLYFCICVDV DN+L YLEAIHNFVEVLNE FHNVCELDLVFNFY+VY+VVDEMFLAGEIRETSQTKVLKQ+  L SL+
Sbjct:    1 MIRFILIQNRAGKTRLAKWYMQFDDDEKQKLIEEVHAVVTVRDAKHTNFVEFRNFKIIYRRYAGLYFCICVDVNDNNLAYLEAIHNFVEVLNEYFHNVCELDLVFNFYKVYTVVDEMFLAGEIRETSQTKVLKQLLMLQSLE 142
[Close]
BLAST of AP complex subunit sigma vs. TrEMBL
Match: A0A183BGN4 (AP complex subunit sigma OS=Echinostoma caproni OX=27848 GN=ECPE_LOCUS18369 PE=3 SV=1)

HSP 1 Score: 268.47 bits (685), Expect = 2.613e-87
Identity = 127/142 (89.44%), Postives = 137/142 (96.48%), Query Frame = 1 
Query:   85 MIRFILIQNRAGKTRLAKWYMTFDDEEKQKLIEEVHALVTVRDAKHTNFVEFRTFKIVYRRYAGLYFCICVDVMDNSLMYLEAIHNFVEVLNELFHNVCELDLVFNFYRVYSVVDEMFLAGEIRETSQTKVLKQMAQLNSLD 510
            MIRFILIQNRAGKTRLAKWYM F+DEEKQKLIEEVHALVTVRDAKHTNFVEFR +K+VYRRYAGLYFC+C+DVMDNSLMYLEAIHNFVEVLNELFHNVCELDLVFNFY+VYSVVDEMFLAGEIRETSQTKVLKQ+   ++L+
Sbjct:    1 MIRFILIQNRAGKTRLAKWYMHFEDEEKQKLIEEVHALVTVRDAKHTNFVEFRNYKVVYRRYAGLYFCVCIDVMDNSLMYLEAIHNFVEVLNELFHNVCELDLVFNFYKVYSVVDEMFLAGEIRETSQTKVLKQILMYSALE 142
[Close]
BLAST of AP complex subunit sigma vs. TrEMBL
Match: C3Z3J8 (AP complex subunit sigma OS=Branchiostoma floridae OX=7739 GN=BRAFLDRAFT_262959 PE=3 SV=1)

HSP 1 Score: 267.7 bits (683), Expect = 4.558e-87
Identity = 130/142 (91.55%), Postives = 135/142 (95.07%), Query Frame = 1 
Query:   85 MIRFILIQNRAGKTRLAKWYMTFDDEEKQKLIEEVHALVTVRDAKHTNFVEFRTFKIVYRRYAGLYFCICVDVMDNSLMYLEAIHNFVEVLNELFHNVCELDLVFNFYRVYSVVDEMFLAGEIRETSQTKVLKQMAQLNSLD 510
            MIRFILIQNRAGKTRLAKWYM FDD+EKQKLIEEVHA VTVRDAKHTNFVEFR FKIVYRRYAGLYFCICVDV DN+LMYLEAIHNFVEVLNE FHNVCELDLVFNFY+VYSVVDEMFLAGEIRETSQTKVLKQ+  LNSL+
Sbjct:    1 MIRFILIQNRAGKTRLAKWYMQFDDDEKQKLIEEVHACVTVRDAKHTNFVEFRNFKIVYRRYAGLYFCICVDVNDNNLMYLEAIHNFVEVLNEYFHNVCELDLVFNFYKVYSVVDEMFLAGEIRETSQTKVLKQLLMLNSLE 142
[Close]
BLAST of AP complex subunit sigma vs. TrEMBL
Match: A0A2P2I5L4 (AP complex subunit sigma OS=Hirondellea gigas OX=1518452 PE=2 SV=1)

HSP 1 Score: 267.7 bits (683), Expect = 4.866e-87
Identity = 128/142 (90.14%), Postives = 136/142 (95.77%), Query Frame = 1 
Query:   85 MIRFILIQNRAGKTRLAKWYMTFDDEEKQKLIEEVHALVTVRDAKHTNFVEFRTFKIVYRRYAGLYFCICVDVMDNSLMYLEAIHNFVEVLNELFHNVCELDLVFNFYRVYSVVDEMFLAGEIRETSQTKVLKQMAQLNSLD 510
            MIRFILIQNRAGKTRLAKWYM FDD+EKQKLIEEVHA+VTVRDAKHTNFVEFR FKIVYRRYAGLYFCICVD+ DN+L+YLEAIHNFVEVLNE FHNVCELDLVFNFY+VYSVVDEMFLAGEIRETSQTKVLKQ+  LNSL+
Sbjct:    1 MIRFILIQNRAGKTRLAKWYMNFDDDEKQKLIEEVHAVVTVRDAKHTNFVEFRNFKIVYRRYAGLYFCICVDISDNNLIYLEAIHNFVEVLNEYFHNVCELDLVFNFYKVYSVVDEMFLAGEIRETSQTKVLKQLLMLNSLE 142
[Close]
BLAST of AP complex subunit sigma vs. TrEMBL
Match: A0A2H1BSX7 (AP complex subunit sigma OS=Fasciola hepatica OX=6192 GN=D915_16058 PE=3 SV=1)

HSP 1 Score: 267.7 bits (683), Expect = 5.310e-87
Identity = 127/142 (89.44%), Postives = 137/142 (96.48%), Query Frame = 1 
Query:   85 MIRFILIQNRAGKTRLAKWYMTFDDEEKQKLIEEVHALVTVRDAKHTNFVEFRTFKIVYRRYAGLYFCICVDVMDNSLMYLEAIHNFVEVLNELFHNVCELDLVFNFYRVYSVVDEMFLAGEIRETSQTKVLKQMAQLNSLD 510
            MIRFILIQNRAGKTRLAKWYM F+DEEKQKLIEEVHALVTVRDAKHTNFVEFR +K+VYRRYAGLYFC+C+DVMDNSLMYLEAIHNFVEVLNELFHNVCELDLVFNFY+VYSVVDEMFLAGEIRETSQTKVLKQ+   ++L+
Sbjct:    1 MIRFILIQNRAGKTRLAKWYMHFEDEEKQKLIEEVHALVTVRDAKHTNFVEFRNYKVVYRRYAGLYFCVCIDVMDNSLMYLEAIHNFVEVLNELFHNVCELDLVFNFYKVYSVVDEMFLAGEIRETSQTKVLKQILVYSALE 142
[Close]
BLAST of AP complex subunit sigma vs. TrEMBL
Match: A0A4S2KEE6 (AP complex subunit sigma OS=Opisthorchis felineus OX=147828 GN=CRM22_011055 PE=3 SV=1)

HSP 1 Score: 267.314 bits (682), Expect = 7.446e-87
Identity = 127/142 (89.44%), Postives = 136/142 (95.77%), Query Frame = 1 
Query:   85 MIRFILIQNRAGKTRLAKWYMTFDDEEKQKLIEEVHALVTVRDAKHTNFVEFRTFKIVYRRYAGLYFCICVDVMDNSLMYLEAIHNFVEVLNELFHNVCELDLVFNFYRVYSVVDEMFLAGEIRETSQTKVLKQMAQLNSLD 510
            MIRFILIQNRAGKTRLAKWYM  DDEEKQKLIEEVHA+VTVRDAKHTNFVEFR +KIVYRRYAGLYFC+C+DVMDNSLMYLEAIHNFVEVLNELFHNVCELDLVFNFY+VYSVVDEMFLAGEIRETSQTKVLKQ+   ++L+
Sbjct:    1 MIRFILIQNRAGKTRLAKWYMHLDDEEKQKLIEEVHAVVTVRDAKHTNFVEFRNYKIVYRRYAGLYFCVCIDVMDNSLMYLEAIHNFVEVLNELFHNVCELDLVFNFYKVYSVVDEMFLAGEIRETSQTKVLKQILMYSALE 142
[Close]
BLAST of AP complex subunit sigma vs. Ensembl Cavefish
Match: ap2s1 (adaptor related protein complex 2 subunit sigma 1 [Source:NCBI gene;Acc:103022522])

HSP 1 Score: 261.922 bits (668), Expect = 3.538e-88
Identity = 125/142 (88.03%), Postives = 133/142 (93.66%), Query Frame = 1 
Query:   85 MIRFILIQNRAGKTRLAKWYMTFDDEEKQKLIEEVHALVTVRDAKHTNFVEFRTFKIVYRRYAGLYFCICVDVMDNSLMYLEAIHNFVEVLNELFHNVCELDLVFNFYRVYSVVDEMFLAGEIRETSQTKVLKQMAQLNSLD 510
            MIRFILIQNRAGKTRLAKWYM FDD+EKQKLIEEVHA+VTVRDAKHTNFVEFR FKI+YRRYAGLYFCICVDV DN+L YLE IHNFVEVLNE FHNVCELDLVFNFY+VY+VVDEMFLAGEIRETSQTKVLKQ+  L SL+
Sbjct:    1 MIRFILIQNRAGKTRLAKWYMQFDDDEKQKLIEEVHAVVTVRDAKHTNFVEFRNFKIIYRRYAGLYFCICVDVTDNNLAYLEGIHNFVEVLNEYFHNVCELDLVFNFYKVYTVVDEMFLAGEIRETSQTKVLKQLLMLQSLE 142
[Close]
BLAST of AP complex subunit sigma vs. Ensembl Cavefish
Match: ap2s1 (adaptor related protein complex 2 subunit sigma 1 [Source:NCBI gene;Acc:103022522])

HSP 1 Score: 261.922 bits (668), Expect = 3.538e-88
Identity = 125/142 (88.03%), Postives = 133/142 (93.66%), Query Frame = 1 
Query:   85 MIRFILIQNRAGKTRLAKWYMTFDDEEKQKLIEEVHALVTVRDAKHTNFVEFRTFKIVYRRYAGLYFCICVDVMDNSLMYLEAIHNFVEVLNELFHNVCELDLVFNFYRVYSVVDEMFLAGEIRETSQTKVLKQMAQLNSLD 510
            MIRFILIQNRAGKTRLAKWYM FDD+EKQKLIEEVHA+VTVRDAKHTNFVEFR FKI+YRRYAGLYFCICVDV DN+L YLE IHNFVEVLNE FHNVCELDLVFNFY+VY+VVDEMFLAGEIRETSQTKVLKQ+  L SL+
Sbjct:    1 MIRFILIQNRAGKTRLAKWYMQFDDDEKQKLIEEVHAVVTVRDAKHTNFVEFRNFKIIYRRYAGLYFCICVDVTDNNLAYLEGIHNFVEVLNEYFHNVCELDLVFNFYKVYTVVDEMFLAGEIRETSQTKVLKQLLMLQSLE 142
[Close]
BLAST of AP complex subunit sigma vs. Ensembl Cavefish
Match: ap2s1 (adaptor related protein complex 2 subunit sigma 1 [Source:NCBI gene;Acc:103022522])

HSP 1 Score: 259.61 bits (662), Expect = 2.821e-87
Identity = 124/141 (87.94%), Postives = 132/141 (93.62%), Query Frame = 1 
Query:   88 IRFILIQNRAGKTRLAKWYMTFDDEEKQKLIEEVHALVTVRDAKHTNFVEFRTFKIVYRRYAGLYFCICVDVMDNSLMYLEAIHNFVEVLNELFHNVCELDLVFNFYRVYSVVDEMFLAGEIRETSQTKVLKQMAQLNSLD 510
            IRFILIQNRAGKTRLAKWYM FDD+EKQKLIEEVHA+VTVRDAKHTNFVEFR FKI+YRRYAGLYFCICVDV DN+L YLE IHNFVEVLNE FHNVCELDLVFNFY+VY+VVDEMFLAGEIRETSQTKVLKQ+  L SL+
Sbjct:    6 IRFILIQNRAGKTRLAKWYMQFDDDEKQKLIEEVHAVVTVRDAKHTNFVEFRNFKIIYRRYAGLYFCICVDVTDNNLAYLEGIHNFVEVLNEYFHNVCELDLVFNFYKVYTVVDEMFLAGEIRETSQTKVLKQLLMLQSLE 146
[Close]
BLAST of AP complex subunit sigma vs. Ensembl Cavefish
Match: ap1s1 (AP-1 complex subunit sigma-1A [Source:NCBI gene;Acc:103041452])

HSP 1 Score: 142.124 bits (357), Expect = 3.833e-41
Identity = 65/140 (46.43%), Postives = 97/140 (69.29%), Query Frame = 1 
Query:   88 IRFILIQNRAGKTRLAKWYMTFDDEEKQKLIEEVHALVTVRDAKHTNFVEFRTFKIVYRRYAGLYFCICVDVMDNSLMYLEAIHNFVEVLNELFHNVCELDLVFNFYRVYSVVDEMFLAGEIRETSQTKVLKQMAQLNSL 507
            +RF+L+ +R GK RL KWY    + +K+K++ E+  +V  R  K  +F+E+R  KIVY+RYA LYFC  V+  DN L+ LE IH FVE+L++ F +VCELD++FNF + Y ++DE  + GEI++TS+  VLK + Q + L
Sbjct:    1 MRFMLLFSRQGKLRLQKWYTATAERDKKKMVRELMQVVLARKPKMCSFLEWRDLKIVYKRYASLYFCCAVEEQDNELITLEVIHRFVELLDKYFGSVCELDIIFNFEKAYFILDEFLMGGEIQDTSKKSVLKAIEQADLL 140
[Close]
BLAST of AP complex subunit sigma vs. Ensembl Cavefish
Match: AP1S2 (AP-1 complex subunit sigma-2 [Source:NCBI gene;Acc:103030203])

HSP 1 Score: 140.584 bits (353), Expect = 1.287e-40
Identity = 65/140 (46.43%), Postives = 96/140 (68.57%), Query Frame = 1 
Query:   88 IRFILIQNRAGKTRLAKWYMTFDDEEKQKLIEEVHALVTVRDAKHTNFVEFRTFKIVYRRYAGLYFCICVDVMDNSLMYLEAIHNFVEVLNELFHNVCELDLVFNFYRVYSVVDEMFLAGEIRETSQTKVLKQMAQLNSL 507
            ++F+L+ +R GK RL KWY+   D+EK+K+  E+   V  R  K  +F+E+R  KIVY+RYA LYFC  ++  DN L+ LE IH +VE+L++ F +VCELD++FNF + Y ++DE  L GE +ETS+  VLK + Q + L
Sbjct:    1 MQFMLLFSRQGKLRLQKWYVPLSDKEKKKITRELVQTVLARKPKMCSFLEWRDLKIVYKRYASLYFCCAIEDQDNELITLEIIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLLGGEAQETSKKNVLKAIEQADLL 140
[Close]
BLAST of AP complex subunit sigma vs. Ensembl Sea Lamprey
Match: ap2s1 (adaptor related protein complex 2 subunit sigma 1 [Source:ZFIN;Acc:ZDB-GENE-040426-2174])

HSP 1 Score: 263.077 bits (671), Expect = 1.982e-89
Identity = 127/142 (89.44%), Postives = 134/142 (94.37%), Query Frame = 1 
Query:   85 MIRFILIQNRAGKTRLAKWYMTFDDEEKQKLIEEVHALVTVRDAKHTNFVEFRTFKIVYRRYAGLYFCICVDVMDNSLMYLEAIHNFVEVLNELFHNVCELDLVFNFYRVYSVVDEMFLAGEIRETSQTKVLKQMAQLNSLD 510
            MIRFILIQNRAGKTRLAKWYM FDD+EKQKLIEEVHA+VTVRDAKHTNFVEFR FKIVYRRYAGLYFCICVDV DN+L YLEAIHNFVEVLNE FHNVCELDLVFNFY+VY+VVDEMFLAGEIRETSQTKVLKQ+  L SL+
Sbjct:    1 MIRFILIQNRAGKTRLAKWYMQFDDDEKQKLIEEVHAVVTVRDAKHTNFVEFRNFKIVYRRYAGLYFCICVDVNDNNLAYLEAIHNFVEVLNEYFHNVCELDLVFNFYKVYTVVDEMFLAGEIRETSQTKVLKQLLMLQSLE 142
[Close]
BLAST of AP complex subunit sigma vs. Ensembl Sea Lamprey
Match: ap3s2 (adaptor related protein complex 3 subunit sigma 2 [Source:ZFIN;Acc:ZDB-GENE-040718-274])

HSP 1 Score: 108.612 bits (270), Expect = 1.086e-28
Identity = 59/148 (39.86%), Postives = 93/148 (62.84%), Query Frame = 1 
Query:   85 MIRFILIQNRAGKTRLAKWYMTFDDEEKQKLIEEVHALVTVRDAKHTNFVEFRT------FKIVYRRYAGLYFCICVDVMDNSLMYLEAIHNFVEVLNELFHNVCELDLVFNFYRVYSVVDEMFLAGEIRETSQTKVLKQMAQLNSLD 510
            MI+ IL+ N  GK RL+K+Y  ++D ++Q +I E   LV+ RD    NF+E  T      +K++YR YA LYF  CVD  ++ L  L+ I  FVE L++ F NVCELDL+F+  +V+ +++EM + G + ET+  +++ Q+   N L+
Sbjct:    1 MIKAILVFNNHGKPRLSKFYKFYEDMQQQ-IIRETFHLVSKRDDNVCNFLEGGTLIGGSDYKLIYRHYATLYFVFCVDSCESELGILDLIQVFVETLDKCFENVCELDLIFHVDKVHYILNEMVMGGMVLETNMNEIVNQIEAQNKLE 147
[Close]
BLAST of AP complex subunit sigma vs. Ensembl Yeast
Match: APS2 (Small subunit of the clathrin-associated adaptor complex AP-2; AP-2 is involved in protein sorting at the plasma membrane; related to the sigma subunit of the mammalian plasma membrane clathrin-associated protein (AP-2) complex [Source:SGD;Acc:S000003819])

HSP 1 Score: 140.969 bits (354), Expect = 7.355e-42
Identity = 70/145 (48.28%), Postives = 105/145 (72.41%), Query Frame = 1 
Query:   88 IRFILIQNRAGKTRLAKWY--MTFDDEEKQKLIEEVHALVTVRDAKH-TNFVEFR-TFKIVYRRYAGLYFCICVDVMDNSLMYLEAIHNFVEVLNELFHNVCELDLVFNFYRVYSVVDEMFLAGEIRETSQTKVLKQMAQLNSLD 510
            ++FIL  N+ G  RL +W+   + D +  Q  I +++ L++ RD KH +NFVEF  + K++YRRYAGLYF + VD++D+  +YL  IH FVEVL+  F NVCELD+VFNFY+VY ++DEMF+ GEI+E S+  +L++++ L+ LD
Sbjct:    3 VQFILCFNKQGVVRLVRWFDVHSSDPQRSQDAIAQIYRLISSRDHKHQSNFVEFSDSTKLIYRRYAGLYFVMGVDLLDDEPIYLCHIHLFVEVLDAFFGNVCELDIVFNFYKVYMIMDEMFIGGEIQEISKDMLLERLSILDRLD 147
[Close]
BLAST of AP complex subunit sigma vs. Ensembl Yeast
Match: APS1 (Small subunit of the clathrin-associated adaptor complex AP-1; AP-1 is involved in protein sorting at the trans-Golgi network; homolog of the sigma subunit of the mammalian clathrin AP-1 complex [Source:SGD;Acc:S000004160])

HSP 1 Score: 120.168 bits (300), Expect = 1.132e-33
Identity = 55/143 (38.46%), Postives = 93/143 (65.03%), Query Frame = 1 
Query:   88 IRFILIQNRAGKTRLAKWYMTFDDEEKQKLIEEVHALVTVRDAKHTNFVEFRTFKIVYRRYAGLYFCICVDV-MDNSLMYLEAIHNFVEVLNELFHNVCELDLVFNFYRVYSVVDEMFLA-GEIRETSQTKVLKQMAQLNSLD 510
            ++++L+ +R GK RL KWY      EK K+++++   +  R  K  N +E+   K+VY+RYA LYF + +   +DN L+ LE IH FVE ++  F NVCELD++FNF +VY +++EM +  G I E+S+ +VL  +  +++++
Sbjct:    4 LKYLLLVSRQGKIRLKKWYTAMSAGEKAKIVKDLTPTILARKPKMCNIIEYNDHKVVYKRYASLYFIVGMTPDVDNELLTLEIIHRFVETMDTYFGNVCELDIIFNFSKVYDILNEMIMCDGSIAESSRKEVLHHVTVMDTME 146
[Close]
BLAST of AP complex subunit sigma vs. Ensembl Yeast
Match: APS3 (Small subunit of the clathrin-associated adaptor complex AP-3; involved in vacuolar protein sorting; related to the sigma subunit of the mammalian clathrin AP-3 complex; suppressor of loss of casein kinase 1 function; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000003561])

HSP 1 Score: 78.5666 bits (192), Expect = 9.770e-18
Identity = 48/157 (30.57%), Postives = 85/157 (54.14%), Query Frame = 1 
Query:   85 MIRFILIQNRAGKTRLAKWYMTFDDEEKQKLIEEVHALVTVRDAK-HTNFV-----------------EFRTFKIVYRRYAGLYFCICVDVMDNSLMYLEAIHNFVEVLNELFHNVCELDLVFNFYRVYSVVDEMFLAGEIRETSQTKVLKQMAQLN 501
            MI  +LI N+  + RL K+Y   D  +++ L+E+V+ L++ R++   ++F+                      +I+Y+ YA LYF   VD  ++ L  L+ I  FVE L+  F  V ELDL+FN+  + SV++E+   G + ET+  +++  + +LN
Sbjct:    1 MIHAVLIFNKKCQPRLVKFYTPVDLPKQKLLLEQVYELISQRNSDFQSSFLVTPPSLLLSNENNNDEVNNEDIQIIYKNYATLYFTFIVDDQESELAILDLIQTFVESLDRCFTEVNELDLIFNWQTLESVLEEIVQGGMVIETNVNRIVASVDELN 157
[Close]
BLAST of AP complex subunit sigma vs. Ensembl Nematostella
Match: EDO42183 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S269])

HSP 1 Score: 258.455 bits (659), Expect = 2.707e-87
Identity = 124/141 (87.94%), Postives = 131/141 (92.91%), Query Frame = 1 
Query:   88 IRFILIQNRAGKTRLAKWYMTFDDEEKQKLIEEVHALVTVRDAKHTNFVEFRTFKIVYRRYAGLYFCICVDVMDNSLMYLEAIHNFVEVLNELFHNVCELDLVFNFYRVYSVVDEMFLAGEIRETSQTKVLKQMAQLNSLD 510
            IRFILIQNRAGKTRLAKWYM FDD+EKQKLIEEVHALVTVRDAKHTNFVEFR FKIVYRRYAGLYFC CVDV DN+L YLEAIHNFVEVLNE FHNVCELDLVFNFY+VYSVVDEMFLAGE+RETSQ+KVLKQ+  L  L+
Sbjct:    2 IRFILIQNRAGKTRLAKWYMNFDDDEKQKLIEEVHALVTVRDAKHTNFVEFRNFKIVYRRYAGLYFCFCVDVSDNNLYYLEAIHNFVEVLNEFFHNVCELDLVFNFYKVYSVVDEMFLAGELRETSQSKVLKQLNMLQQLE 142
[Close]
BLAST of AP complex subunit sigma vs. Ensembl Nematostella
Match: EDO45252 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RTE2])

HSP 1 Score: 130.954 bits (328), Expect = 1.735e-37
Identity = 57/133 (42.86%), Postives = 92/133 (69.17%), Query Frame = 1 
Query:   94 FILIQNRAGKTRLAKWYMTFDDEEKQKLIEEVHALVTVRDAKHTNFVEFRTFKIVYRRYAGLYFCICVDVMDNSLMYLEAIHNFVEVLNELFHNVCELDLVFNFYRVYSVVDEMFLAGEIRETSQTKVLKQMA 492
            F+L+ +R GK RL KWY     +EK+K+  ++   V  R  K  +F+E++  K+ Y+RYA LYFC+ ++  DN L+ LE IH +VE+L++ F +VCELD++FNF + Y ++DE+ + GE++ETS+  VLK ++
Sbjct:    2 FMLLFSRQGKIRLQKWYTAISQKEKKKITRDLVTTVLSRKPKMCSFLEYKDMKVCYKRYASLYFCVGIENDDNELLTLEVIHRYVELLDKYFGSVCELDIIFNFEKAYFMLDELLIGGEVQETSKKNVLKAIS 134
[Close]
BLAST of AP complex subunit sigma vs. Ensembl Nematostella
Match: EDO38137 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SDU6])

HSP 1 Score: 120.553 bits (301), Expect = 1.646e-33
Identity = 60/141 (42.55%), Postives = 92/141 (65.25%), Query Frame = 1 
Query:   85 MIRFILIQNRAGKTRLAKWYMTFDDEEKQKLIEEVHALVTVRDAKHTNFVEFRTFKIVYRRYAGLYFCICVDVMDNSLMYLEAIHNFVEVLNELFHNVCELDLVFNFYRVYSVVDEMFLAGEIRETSQTKVLKQMAQLNSL 507
            M++FILI N+ G TRL+++Y     E++  L  E+      R     +F+E++ FK VYRRYA LYF I +D  +N L  +E IHNFVE+L+  F +VCELD++FN  +V+ ++DEM + G I ET++ +VL  + +L+ L
Sbjct:    1 MLKFILIVNKQGHTRLSQYYEYTKIEDRVSLEAEIIRKCLARSENQCSFIEYQNFKAVYRRYASLYFIIGIDSTENELGIMEFIHNFVEILDRYFDSVCELDIMFNIDKVHMLLDEMVMNGHIVETNKNRVLAPVTELDRL 141
[Close]
BLAST of AP complex subunit sigma vs. Ensembl Nematostella
Match: EDO42407 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S1Q2])

HSP 1 Score: 111.309 bits (277), Expect = 1.988e-29
Identity = 59/148 (39.86%), Postives = 92/148 (62.16%), Query Frame = 1 
Query:   85 MIRFILIQNRAGKTRLAKWYMTFDDEEKQKLIEEVHALVTVRDAKHTNFVEFRT------FKIVYRRYAGLYFCICVDVMDNSLMYLEAIHNFVEVLNELFHNVCELDLVFNFYRVYSVVDEMFLAGEIRETSQTKVLKQMAQLNSLD 510
            MI+ ILI N  GK RL K+Y  + ++ +Q++I+E   LV+ RD    NF+E  +      FK+VYR YA LYF  CVD  ++ L  L+ I  FVE L++ F NVCELDL+F+  +V+ ++ E+ + G + ET+ +++L  +   N L+
Sbjct:    1 MIKGILIFNNHGKPRLTKFYQHYSEDMQQQIIKETFHLVSRRDDNVCNFLEGGSLIGGADFKLVYRHYATLYFVFCVDSSESELGILDLIQVFVETLDKCFENVCELDLIFHMDKVHHILAEIVMGGMVLETNMSEILTHIEAQNKLE 148
[Close]
BLAST of AP complex subunit sigma vs. Ensembl Medaka
Match: ap2s1 (adaptor related protein complex 2 subunit sigma 1 [Source:NCBI gene;Acc:101160086])

HSP 1 Score: 261.922 bits (668), Expect = 3.516e-88
Identity = 125/142 (88.03%), Postives = 133/142 (93.66%), Query Frame = 1 
Query:   85 MIRFILIQNRAGKTRLAKWYMTFDDEEKQKLIEEVHALVTVRDAKHTNFVEFRTFKIVYRRYAGLYFCICVDVMDNSLMYLEAIHNFVEVLNELFHNVCELDLVFNFYRVYSVVDEMFLAGEIRETSQTKVLKQMAQLNSLD 510
            MIRFILIQNRAGKTRLAKWYM FDD+EKQKLIEEVHA+VTVRDAKHTNFVEFR FKI+YRRYAGLYFCICVDV DN+L YLE IHNFVEVLNE FHNVCELDLVFNFY+VY+VVDEMFLAGEIRETSQTKVLKQ+  L SL+
Sbjct:    1 MIRFILIQNRAGKTRLAKWYMQFDDDEKQKLIEEVHAVVTVRDAKHTNFVEFRNFKIIYRRYAGLYFCICVDVTDNNLAYLEGIHNFVEVLNEYFHNVCELDLVFNFYKVYTVVDEMFLAGEIRETSQTKVLKQLLMLQSLE 142
[Close]
BLAST of AP complex subunit sigma vs. Ensembl Medaka
Match: ap1s1 (adaptor related protein complex 1 subunit sigma 1 [Source:NCBI gene;Acc:101154904])

HSP 1 Score: 142.51 bits (358), Expect = 2.428e-41
Identity = 64/141 (45.39%), Postives = 98/141 (69.50%), Query Frame = 1 
Query:   85 MIRFILIQNRAGKTRLAKWYMTFDDEEKQKLIEEVHALVTVRDAKHTNFVEFRTFKIVYRRYAGLYFCICVDVMDNSLMYLEAIHNFVEVLNELFHNVCELDLVFNFYRVYSVVDEMFLAGEIRETSQTKVLKQMAQLNSL 507
            M+RF+L+ +R GK RL KWY    + +K+K++ E+  +V  R  K  +F+E++  KIVY+RYA LYFC  ++  DN L+ LE IH FVE+L++ F +VCELD++FNF + Y ++DE  + GEI++TS+  VLK + Q + L
Sbjct:    1 MMRFMLLFSRQGKLRLQKWYTATAERDKKKMVRELMQIVLARKPKMCSFLEWKDLKIVYKRYASLYFCCAIEEQDNELITLEVIHRFVELLDKYFGSVCELDIIFNFEKAYFILDEFLMGGEIQDTSKKSVLKAIEQADLL 141
[Close]
BLAST of AP complex subunit sigma vs. Ensembl Medaka
Match: zgc:162858 (AP-1 complex subunit sigma-2 [Source:NCBI gene;Acc:101174095])

HSP 1 Score: 140.584 bits (353), Expect = 2.006e-40
Identity = 65/140 (46.43%), Postives = 96/140 (68.57%), Query Frame = 1 
Query:   88 IRFILIQNRAGKTRLAKWYMTFDDEEKQKLIEEVHALVTVRDAKHTNFVEFRTFKIVYRRYAGLYFCICVDVMDNSLMYLEAIHNFVEVLNELFHNVCELDLVFNFYRVYSVVDEMFLAGEIRETSQTKVLKQMAQLNSL 507
            ++F+L+ +R GK RL KWY+   D+EK+K+  E+   V  R  K  +F+E+R  KIVY+RYA LYFC  ++  DN L+ LE IH +VE+L++ F +VCELD++FNF + Y ++DE  L GE +ETS+  VLK + Q + L
Sbjct:    1 MQFMLLFSRQGKLRLQKWYVPLSDKEKKKITRELVQTVLARKPKMCSFLEWRDLKIVYKRYASLYFCCAIEDQDNELITLEIIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLLGGEAQETSKKNVLKAIEQADLL 140
[Close]
BLAST of AP complex subunit sigma vs. Ensembl Medaka
Match: zgc:162858 (AP-1 complex subunit sigma-2 [Source:NCBI gene;Acc:101174095])

HSP 1 Score: 140.198 bits (352), Expect = 3.720e-40
Identity = 65/140 (46.43%), Postives = 96/140 (68.57%), Query Frame = 1 
Query:   88 IRFILIQNRAGKTRLAKWYMTFDDEEKQKLIEEVHALVTVRDAKHTNFVEFRTFKIVYRRYAGLYFCICVDVMDNSLMYLEAIHNFVEVLNELFHNVCELDLVFNFYRVYSVVDEMFLAGEIRETSQTKVLKQMAQLNSL 507
            ++F+L+ +R GK RL KWY+   D+EK+K+  E+   V  R  K  +F+E+R  KIVY+RYA LYFC  ++  DN L+ LE IH +VE+L++ F +VCELD++FNF + Y ++DE  L GE +ETS+  VLK + Q + L
Sbjct:   21 MQFMLLFSRQGKLRLQKWYVPLSDKEKKKITRELVQTVLARKPKMCSFLEWRDLKIVYKRYASLYFCCAIEDQDNELITLEIIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLLGGEAQETSKKNVLKAIEQADLL 160
[Close]
BLAST of AP complex subunit sigma vs. Ensembl Medaka
Match: zgc:162858 (AP-1 complex subunit sigma-2 [Source:NCBI gene;Acc:101174095])

HSP 1 Score: 140.969 bits (354), Expect = 7.707e-40
Identity = 65/140 (46.43%), Postives = 96/140 (68.57%), Query Frame = 1 
Query:   88 IRFILIQNRAGKTRLAKWYMTFDDEEKQKLIEEVHALVTVRDAKHTNFVEFRTFKIVYRRYAGLYFCICVDVMDNSLMYLEAIHNFVEVLNELFHNVCELDLVFNFYRVYSVVDEMFLAGEIRETSQTKVLKQMAQLNSL 507
            ++F+L+ +R GK RL KWY+   D+EK+K+  E+   V  R  K  +F+E+R  KIVY+RYA LYFC  ++  DN L+ LE IH +VE+L++ F +VCELD++FNF + Y ++DE  L GE +ETS+  VLK + Q + L
Sbjct:   21 MQFMLLFSRQGKLRLQKWYVPLSDKEKKKITRELVQTVLARKPKMCSFLEWRDLKIVYKRYASLYFCCAIEDQDNELITLEIIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLLGGEAQETSKKNVLKAIEQADLL 160
[Close]
BLAST of AP complex subunit sigma vs. Planmine SMEST
Match: SMESG000038889.1 (SMESG000038889.1)

HSP 1 Score: 292.352 bits (747), Expect = 2.369e-100
Identity = 142/142 (100.00%), Postives = 142/142 (100.00%), Query Frame = 1 
Query:   85 MIRFILIQNRAGKTRLAKWYMTFDDEEKQKLIEEVHALVTVRDAKHTNFVEFRTFKIVYRRYAGLYFCICVDVMDNSLMYLEAIHNFVEVLNELFHNVCELDLVFNFYRVYSVVDEMFLAGEIRETSQTKVLKQMAQLNSLD 510
            MIRFILIQNRAGKTRLAKWYMTFDDEEKQKLIEEVHALVTVRDAKHTNFVEFRTFKIVYRRYAGLYFCICVDVMDNSLMYLEAIHNFVEVLNELFHNVCELDLVFNFYRVYSVVDEMFLAGEIRETSQTKVLKQMAQLNSLD
Sbjct:    1 MIRFILIQNRAGKTRLAKWYMTFDDEEKQKLIEEVHALVTVRDAKHTNFVEFRTFKIVYRRYAGLYFCICVDVMDNSLMYLEAIHNFVEVLNELFHNVCELDLVFNFYRVYSVVDEMFLAGEIRETSQTKVLKQMAQLNSLD 142
[Close]
BLAST of AP complex subunit sigma vs. Planmine SMEST
Match: SMESG000038894.1 (SMESG000038894.1)

HSP 1 Score: 287.345 bits (734), Expect = 2.203e-98
Identity = 137/142 (96.48%), Postives = 141/142 (99.30%), Query Frame = 1 
Query:   85 MIRFILIQNRAGKTRLAKWYMTFDDEEKQKLIEEVHALVTVRDAKHTNFVEFRTFKIVYRRYAGLYFCICVDVMDNSLMYLEAIHNFVEVLNELFHNVCELDLVFNFYRVYSVVDEMFLAGEIRETSQTKVLKQMAQLNSLD 510
            M+RFILIQNRAGKTRLAKWYMTFDDEEKQKLIEEVHALVTVRDAKHTNFVEFRTFKIVYRRYAGLYFCICVDVMDNSLMYLEAIHNFVEVLNE+FHNVCELDLVFNFY+VYSVVDEMFLAGEIRETSQTK+LKQM QLNSLD
Sbjct:    1 MLRFILIQNRAGKTRLAKWYMTFDDEEKQKLIEEVHALVTVRDAKHTNFVEFRTFKIVYRRYAGLYFCICVDVMDNSLMYLEAIHNFVEVLNEMFHNVCELDLVFNFYKVYSVVDEMFLAGEIRETSQTKILKQMTQLNSLD 142
[Close]
BLAST of AP complex subunit sigma vs. Planmine SMEST
Match: SMESG000063235.1 (SMESG000063235.1)

HSP 1 Score: 140.969 bits (354), Expect = 7.472e-41
Identity = 65/133 (48.87%), Postives = 96/133 (72.18%), Query Frame = 1 
Query:   85 MIRFILIQNRAGKTRLAKWYMTFDDEEKQKLIEEVHALVTVRDAKHTNFVEFRTFKIVYRRYAGLYFCICVDVMDNSLMYLEAIHNFVEVLNELFHNVCELDLVFNFYRVYSVVDEMFLAGEIRETSQTKVLK 483
            M++F+L+ +R GK RL KWY+   D+ ++K++ E+ +LV  R  K   F+E++  KIVYRRYA LYFC  V+  DN L+ LE IH +VE+L++ F +VCELD++FNF + Y ++DE  LAGE++ETS+  VLK
Sbjct:    1 MMQFMLLFSRQGKVRLQKWYVAHSDKTRKKILRELTSLVLTRKPKMCAFIEWKDLKIVYRRYASLYFCCAVEREDNELVTLEIIHRYVELLDKYFGSVCELDIIFNFEKAYFMLDEFMLAGEVQETSKKNVLK 133
[Close]
BLAST of AP complex subunit sigma vs. Planmine SMEST
Match: SMESG000063235.1 (SMESG000063235.1)

HSP 1 Score: 140.969 bits (354), Expect = 7.761e-41
Identity = 65/133 (48.87%), Postives = 96/133 (72.18%), Query Frame = 1 
Query:   85 MIRFILIQNRAGKTRLAKWYMTFDDEEKQKLIEEVHALVTVRDAKHTNFVEFRTFKIVYRRYAGLYFCICVDVMDNSLMYLEAIHNFVEVLNELFHNVCELDLVFNFYRVYSVVDEMFLAGEIRETSQTKVLK 483
            M++F+L+ +R GK RL KWY+   D+ ++K++ E+ +LV  R  K   F+E++  KIVYRRYA LYFC  V+  DN L+ LE IH +VE+L++ F +VCELD++FNF + Y ++DE  LAGE++ETS+  VLK
Sbjct:    1 MMQFMLLFSRQGKVRLQKWYVAHSDKTRKKILRELTSLVLTRKPKMCAFIEWKDLKIVYRRYASLYFCCAVEREDNELVTLEIIHRYVELLDKYFGSVCELDIIFNFEKAYFMLDEFMLAGEVQETSKKNVLK 133
[Close]
BLAST of AP complex subunit sigma vs. Planmine SMEST
Match: SMESG000063235.1 (SMESG000063235.1)

HSP 1 Score: 138.658 bits (348), Expect = 4.844e-40
Identity = 64/132 (48.48%), Postives = 95/132 (71.97%), Query Frame = 1 
Query:   88 IRFILIQNRAGKTRLAKWYMTFDDEEKQKLIEEVHALVTVRDAKHTNFVEFRTFKIVYRRYAGLYFCICVDVMDNSLMYLEAIHNFVEVLNELFHNVCELDLVFNFYRVYSVVDEMFLAGEIRETSQTKVLK 483
            ++F+L+ +R GK RL KWY+   D+ ++K++ E+ +LV  R  K   F+E++  KIVYRRYA LYFC  V+  DN L+ LE IH +VE+L++ F +VCELD++FNF + Y ++DE  LAGE++ETS+  VLK
Sbjct:    1 MQFMLLFSRQGKVRLQKWYVAHSDKTRKKILRELTSLVLTRKPKMCAFIEWKDLKIVYRRYASLYFCCAVEREDNELVTLEIIHRYVELLDKYFGSVCELDIIFNFEKAYFMLDEFMLAGEVQETSKKNVLK 132
The following BLAST results are available for this feature:
BLAST of AP complex subunit sigma vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
AP2S12.960e-8888.73adaptor related protein complex 2 subunit sigma 1 ... [more]
AP2S12.744e-8788.65adaptor related protein complex 2 subunit sigma 1 ... [more]
AP2S15.482e-8788.65adaptor related protein complex 2 subunit sigma 1 ... [more]
AP2S19.278e-8580.77adaptor related protein complex 2 subunit sigma 1 ... [more]
AP2S11.317e-7186.89adaptor related protein complex 2 subunit sigma 1 ... [more]
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BLAST of AP complex subunit sigma vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 3
Match NameE-valueIdentityDescription
aps-24.136e-8888.73AP complex subunit sigma [Source:UniProtKB/TrEMBL... [more]
aps-18.325e-4145.59AP complex subunit sigma [Source:UniProtKB/TrEMBL... [more]
aps-31.904e-2837.41AdaPtin, Small chain (Clathrin associated complex)... [more]
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BLAST of AP complex subunit sigma vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
AP-2sigma5.999e-9090.85gene:FBgn0043012 transcript:FBtr0084103[more]
AP-1sigma2.090e-4045.39gene:FBgn0039132 transcript:FBtr0335244[more]
AP-1sigma2.206e-4045.39gene:FBgn0039132 transcript:FBtr0305039[more]
AP-1sigma2.206e-4045.39gene:FBgn0039132 transcript:FBtr0305040[more]
AP-1sigma2.352e-4045.39gene:FBgn0039132 transcript:FBtr0084496[more]
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BLAST of AP complex subunit sigma vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ap2s11.045e-8888.73adaptor related protein complex 2 subunit sigma 1 ... [more]
ap1s18.617e-4246.81adaptor related protein complex 1 subunit sigma 1 ... [more]
ap1s14.523e-4146.43adaptor related protein complex 1 subunit sigma 1 ... [more]
ap1s14.523e-4146.43adaptor related protein complex 1 subunit sigma 1 ... [more]
ap1s3a6.266e-4144.68adaptor related protein complex 1 subunit sigma 3a... [more]
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BLAST of AP complex subunit sigma vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ap2s11.489e-8888.73adaptor related protein complex 2 subunit sigma 1 ... [more]
ap2s11.881e-8788.65adaptor related protein complex 2 subunit sigma 1 ... [more]
ap1s32.877e-4147.37adaptor related protein complex 1 subunit sigma 3 ... [more]
tbkbp18.424e-4146.43TBK1 binding protein 1 [Source:Xenbase;Acc:XB-GENE... [more]
plekha32.448e-4045.00pleckstrin homology domain containing A3 [Source:X... [more]
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BLAST of AP complex subunit sigma vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Ap2s12.032e-8888.73adaptor-related protein complex 2, sigma 1 subunit... [more]
Ap2s13.953e-5085.71adaptor-related protein complex 2, sigma 1 subunit... [more]
Ap1s11.272e-4143.97adaptor protein complex AP-1, sigma 1 [Source:MGI ... [more]
Ap1s11.309e-4143.97adaptor protein complex AP-1, sigma 1 [Source:MGI ... [more]
Ap1s25.204e-4146.43adaptor-related protein complex 1, sigma 2 subunit... [more]
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BLAST of AP complex subunit sigma vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|P62744|AP2S1_RAT1.422e-8788.73AP-2 complex subunit sigma OS=Rattus norvegicus OX... [more]
sp|Q5R940|AP2S1_PONAB1.422e-8788.73AP-2 complex subunit sigma OS=Pongo abelii OX=9601... [more]
sp|P62743|AP2S1_MOUSE1.422e-8788.73AP-2 complex subunit sigma OS=Mus musculus OX=1009... [more]
sp|P53680|AP2S1_HUMAN1.422e-8788.73AP-2 complex subunit sigma OS=Homo sapiens OX=9606... [more]
sp|Q17QC5|AP2S1_BOVIN1.422e-8788.73AP-2 complex subunit sigma OS=Bos taurus OX=9913 G... [more]
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BLAST of AP complex subunit sigma vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A183BGN42.613e-8789.44AP complex subunit sigma OS=Echinostoma caproni OX... [more]
C3Z3J84.558e-8791.55AP complex subunit sigma OS=Branchiostoma floridae... [more]
A0A2P2I5L44.866e-8790.14AP complex subunit sigma OS=Hirondellea gigas OX=1... [more]
A0A2H1BSX75.310e-8789.44AP complex subunit sigma OS=Fasciola hepatica OX=6... [more]
A0A4S2KEE67.446e-8789.44AP complex subunit sigma OS=Opisthorchis felineus ... [more]
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BLAST of AP complex subunit sigma vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ap2s13.538e-8888.03adaptor related protein complex 2 subunit sigma 1 ... [more]
ap2s13.538e-8888.03adaptor related protein complex 2 subunit sigma 1 ... [more]
ap2s12.821e-8787.94adaptor related protein complex 2 subunit sigma 1 ... [more]
ap1s13.833e-4146.43AP-1 complex subunit sigma-1A [Source:NCBI gene;Ac... [more]
AP1S21.287e-4046.43AP-1 complex subunit sigma-2 [Source:NCBI gene;Acc... [more]
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BLAST of AP complex subunit sigma vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 2
Match NameE-valueIdentityDescription
ap2s11.982e-8989.44adaptor related protein complex 2 subunit sigma 1 ... [more]
ap3s21.086e-2839.86adaptor related protein complex 3 subunit sigma 2 ... [more]
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BLAST of AP complex subunit sigma vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 3
Match NameE-valueIdentityDescription
APS27.355e-4248.28Small subunit of the clathrin-associated adaptor c... [more]
APS11.132e-3338.46Small subunit of the clathrin-associated adaptor c... [more]
APS39.770e-1830.57Small subunit of the clathrin-associated adaptor c... [more]
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BLAST of AP complex subunit sigma vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 4
Match NameE-valueIdentityDescription
EDO421832.707e-8787.94Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO452521.735e-3742.86Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO381371.646e-3342.55Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO424071.988e-2939.86Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of AP complex subunit sigma vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ap2s13.516e-8888.03adaptor related protein complex 2 subunit sigma 1 ... [more]
ap1s12.428e-4145.39adaptor related protein complex 1 subunit sigma 1 ... [more]
zgc:1628582.006e-4046.43AP-1 complex subunit sigma-2 [Source:NCBI gene;Acc... [more]
zgc:1628583.720e-4046.43AP-1 complex subunit sigma-2 [Source:NCBI gene;Acc... [more]
zgc:1628587.707e-4046.43AP-1 complex subunit sigma-2 [Source:NCBI gene;Acc... [more]
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BLAST of AP complex subunit sigma vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000038889.12.369e-100100.00SMESG000038889.1[more]
SMESG000038894.12.203e-9896.48SMESG000038894.1[more]
SMESG000063235.17.472e-4148.87SMESG000063235.1[more]
SMESG000063235.17.761e-4148.87SMESG000063235.1[more]
SMESG000063235.14.844e-4048.48SMESG000063235.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30008812 ID=SMED30008812|Name=AP complex subunit sigma|organism=Schmidtea mediterranea sexual|type=transcript|length=1019bp
TTAGTATTTACTGTTCCTTTATTTTAATTTAATTATAGTGTTATTATTTC
ACTTGAATAAGAAAAACTTAAGAATTTATTACTGATGATACGATTTATTT
TGATTCAAAATCGAGCTGGTAAAACTCGCTTGGCTAAATGGTACATGACA
TTCGATGATGAAGAAAAACAAAAGTTGATTGAAGAAGTGCATGCCTTGGT
GACTGTTAGAGATGCAAAACATACAAATTTTGTTGAATTTAGAACATTTA
AAATAGTCTATAGACGTTATGCTGGGTTATATTTTTGTATTTGTGTTGAT
GTTATGGACAACAGCTTAATGTATTTAGAAGCTATTCATAATTTTGTAGA
GGTTTTAAATGAATTATTTCATAATGTTTGTGAATTGGATTTAGTTTTTA
ATTTTTATCGAGTTTATAGTGTTGTTGATGAAATGTTTCTTGCTGGTGAA
ATAAGGGAAACCAGCCAGACCAAAGTATTAAAACAGATGGCTCAGTTGAA
CTCGTTAGACTAAATAGTTTTTAAATAAACAAATGCTAAAGCCAAATTGT
TTTTGAGTATTTCCACAGGTTTTGTGAGGATAATATTTTTTGTCTAATTT
AGCTACTTTTTATCAGATTTTATGAAATATCTTAATTAATTGTTTGATTA
GTGAATAAATGTTGATAAAGCCTTTAAATATAATTAATTTTTGAGACTAT
TTTACTAATTATGTTATATTTTGGTGATTTCCAGGGTTCTGTGCACGAAA
AAGCTGAAAGTTTATGTAATATTACTAGATATTAATGTTAAGAATCCGCA
ATTTGTACACTATTAATAAAATATCACAAGGCTATCTTTCTGCTCACTTC
CAAAAATGAGAATTGTATCAAATTAAGTAATATCTGGTGCAAATTATTCG
CTATTTTGCAATTGTAACCTGGAAGCCTTCAACTCTGACTTTAGATTGTT
TTTAATAAATGTCCATATTTACGAACTTTTCTGATGTGGTTTACTAGAAA
CTTGTGTAAGAAGTTCTAA
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protein sequence of SMED30008812-orf-1

>SMED30008812-orf-1 ID=SMED30008812-orf-1|Name=SMED30008812-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=143bp
MIRFILIQNRAGKTRLAKWYMTFDDEEKQKLIEEVHALVTVRDAKHTNFV
EFRTFKIVYRRYAGLYFCICVDVMDNSLMYLEAIHNFVEVLNELFHNVCE
LDLVFNFYRVYSVVDEMFLAGEIRETSQTKVLKQMAQLNSLD*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: molecular function
TermDefinition
GO:0035615clathrin adaptor activity
GO:0008565protein transporter activity
Vocabulary: biological process
TermDefinition
GO:0072583clathrin-dependent endocytosis
GO:0015031protein transport
GO:0016192vesicle-mediated transport
GO:0006886intracellular protein transport
GO:0006810transport
GO:0006897endocytosis
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000016pharynx
PLANA:0000026gut
PLANA:0000070intestinal phagocyte
Vocabulary: INTERPRO
TermDefinition
IPR027156APS2
IPR011012Longin-like_dom_sf
IPR022775AP_mu_sigma_su
IPR016635AP_complex_ssu
IPR000804Clathrin_sm-chain_CS
Vocabulary: cellular component
TermDefinition
GO:0030117membrane coat
GO:0005794Golgi apparatus
GO:0005886plasma membrane
GO:0005905clathrin-coated pit
GO:0016020membrane
GO:0030121AP-1 adaptor complex
GO:0030122AP-2 adaptor complex
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR022775AP complex, mu/sigma subunitPFAMPF01217Clat_adaptor_scoord: 1..141
e-value: 1.3E-60
score: 203.4
IPR016635Adaptor protein complex, sigma subunitPIRSFPIRSF015588AP_complex_sigmacoord: 1..142
e-value: 7.2E-62
score: 205.4
IPR016635Adaptor protein complex, sigma subunitPANTHERPTHR11753CLATHRIN COAT ASSEMBLY PROTEINcoord: 1..141
NoneNo IPR availableGENE3DG3DSA:3.30.450.60coord: 1..142
e-value: 5.8E-55
score: 187.2
NoneNo IPR availableCDDcd14833AP2_sigmacoord: 1..141
e-value: 1.21399E-90
score: 257.501
IPR027156AP-2 complex subunit sigmaPANTHERPTHR11753:SF6AP-2 COMPLEX SUBUNIT SIGMAcoord: 1..141
IPR000804Clathrin adaptor complex, small chainPROSITEPS00989CLAT_ADAPTOR_Scoord: 57..67
IPR011012Longin-like domain superfamilySUPERFAMILYSSF64356SNARE-likecoord: 1..137