cAMP-dependent protein kinase type II regulatory subunit
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30008798 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 13Note: Hover over icons to view figure legend
Homology
BLAST of cAMP-dependent protein kinase type II regulatory subunit vs. Ensembl Human
Match: PRKAR2B (protein kinase cAMP-dependent type II regulatory subunit beta [Source:HGNC Symbol;Acc:HGNC:9392]) HSP 1 Score: 214.157 bits (544), Expect = 2.615e-64 Identity = 130/403 (32.26%), Postives = 211/403 (52.36%), Query Frame = 1
Query: 97 LTEVIEEFKKQVEIANPKDIIAYAATYFTKKVAQENESNDT-----------EFDKSLDYDSSSEDGDSLKEIMSNDKSKMKLVQTS-------NVP-------RQSITCESFDPSSIDDETFEKNRKIYPKTPKQMDKITDILETIFFFNCLDEIQFSKIIQSMFFIEVFKGDEIIKENDPGNNFYVIDYGTFTASNKSKSIYEV---YKGEGFFGELALLYNCPRSASVIADTDGGLWVIDRVTFRQLILKSAYQKRQRYLKFISSVPLLEDLTKYEQCNLADALKTKTINN-EKVISQGDAGDKMYF-------IXXXXXXXXXXXXXXXXXXSRLKAGDYFGEVALLANIPRIANVYALGYTKLAELDAKSYTRLLGPCIDNMRKNFTKYRSQLEKLLS 1197
LTE+++ F +V P D++ +A +FT+ + QENE T + + + S+ + +E M +D + + + N P R S+ E+++P +D+ ++R I+PKT Q +++ + + I F LD Q S+++ +MF V G+ +I + D G+NFYVID GTF K + Y G FGELAL+YN PR+A++ A + G LW +DRVTFR++I+K+ +KR+ Y FI S+P L+ L E+ + D + TK N+ E++I+QGD+ D + I + E +R G YFGE+AL+ N PR A+ +A+G K +D +++ RLLGPC++ M++N Y QL L
Sbjct: 9 LTELLQGFTVEVLRHQPADLLEFALQHFTR-LQQENERKGTARFGHEGRTWGDLGAAAGGGTPSKGVNFAEEPMQSDSEDGEEEEAAPADAGAFNAPVINRFTRRASVCAEAYNPDEEEDDA--ESRIIHPKTDDQRNRLQEACKDILLFKNLDPEQMSQVLDAMFEKLVKDGEHVIDQGDDGDNFYVIDRGTFDIYVKCDGVGRCVGNYDNRGSFGELALMYNTPRAATITATSPGALWGLDRVTFRRIIVKNNAKKRKMYESFIESLPFLKSLEFSERLKVVDVIGTKVYNDGEQIIAQGDSADSFFIVESGEVKITMKRKGKSEVEENGAVEIARCSRGQYFGELALVTNKPRAASAHAIGTVKCLAMDVQAFERLLGPCMEIMKRNIATYEEQLVALFG 408
BLAST of cAMP-dependent protein kinase type II regulatory subunit vs. Ensembl Human
Match: PRKAR2B (protein kinase cAMP-dependent type II regulatory subunit beta [Source:HGNC Symbol;Acc:HGNC:9392]) HSP 1 Score: 214.157 bits (544), Expect = 2.615e-64 Identity = 130/403 (32.26%), Postives = 211/403 (52.36%), Query Frame = 1
Query: 97 LTEVIEEFKKQVEIANPKDIIAYAATYFTKKVAQENESNDT-----------EFDKSLDYDSSSEDGDSLKEIMSNDKSKMKLVQTS-------NVP-------RQSITCESFDPSSIDDETFEKNRKIYPKTPKQMDKITDILETIFFFNCLDEIQFSKIIQSMFFIEVFKGDEIIKENDPGNNFYVIDYGTFTASNKSKSIYEV---YKGEGFFGELALLYNCPRSASVIADTDGGLWVIDRVTFRQLILKSAYQKRQRYLKFISSVPLLEDLTKYEQCNLADALKTKTINN-EKVISQGDAGDKMYF-------IXXXXXXXXXXXXXXXXXXSRLKAGDYFGEVALLANIPRIANVYALGYTKLAELDAKSYTRLLGPCIDNMRKNFTKYRSQLEKLLS 1197
LTE+++ F +V P D++ +A +FT+ + QENE T + + + S+ + +E M +D + + + N P R S+ E+++P +D+ ++R I+PKT Q +++ + + I F LD Q S+++ +MF V G+ +I + D G+NFYVID GTF K + Y G FGELAL+YN PR+A++ A + G LW +DRVTFR++I+K+ +KR+ Y FI S+P L+ L E+ + D + TK N+ E++I+QGD+ D + I + E +R G YFGE+AL+ N PR A+ +A+G K +D +++ RLLGPC++ M++N Y QL L
Sbjct: 9 LTELLQGFTVEVLRHQPADLLEFALQHFTR-LQQENERKGTARFGHEGRTWGDLGAAAGGGTPSKGVNFAEEPMQSDSEDGEEEEAAPADAGAFNAPVINRFTRRASVCAEAYNPDEEEDDA--ESRIIHPKTDDQRNRLQEACKDILLFKNLDPEQMSQVLDAMFEKLVKDGEHVIDQGDDGDNFYVIDRGTFDIYVKCDGVGRCVGNYDNRGSFGELALMYNTPRAATITATSPGALWGLDRVTFRRIIVKNNAKKRKMYESFIESLPFLKSLEFSERLKVVDVIGTKVYNDGEQIIAQGDSADSFFIVESGEVKITMKRKGKSEVEENGAVEIARCSRGQYFGELALVTNKPRAASAHAIGTVKCLAMDVQAFERLLGPCMEIMKRNIATYEEQLVALFG 408
BLAST of cAMP-dependent protein kinase type II regulatory subunit vs. Ensembl Human
Match: PRKAR2A (protein kinase cAMP-dependent type II regulatory subunit alpha [Source:HGNC Symbol;Acc:HGNC:9391]) HSP 1 Score: 213.386 bits (542), Expect = 3.195e-64 Identity = 134/389 (34.45%), Postives = 223/389 (57.33%), Query Frame = 1
Query: 97 LTEVIEEFKKQVEIANPKDIIAYAATYFTK-KVAQENES--NDTEFDKSLDYDSSSEDGDSLKEIMSNDKSKMKLVQTSNVP-----RQSITCESFDPSSIDDETFEKNRKIYPKTPKQMDKITDILETIFFFNCLDEIQFSKIIQSMFFIEVFKGDE-IIKENDPGNNFYVIDYGTF----TASNKSKSIYEVYKGEGFFGELALLYNCPRSASVIADTDGGLWVIDRVTFRQLILKSAYQKRQRYLKFISSVPLLEDLTKYEQCNLADALKTKTI-NNEKVISQGDAGDKMYFIXXXXXXXXXXXXXXX--------XXXSRLKAGDYFGEVALLANIPRIANVYALGYTKLAELDAKSYTRLLGPCIDNMRKNFTKYRSQLEKLLS 1197
LTE+++ + +V P D++ +A YFT+ + A+ S +SL + D + + + +S+ VP R S+ E+++P +++T R I+PKT +Q ++ + + I F LD+ Q S+++ +MF + K DE +I + D G+NFYVI+ GT+ T N+++S+ + Y G FGELAL+YN PR+A+++A ++G LW +DRVTFR++I+K+ +KR+ + FI SVPLL+ L E+ + D + K + E++I+QG+ D Y IE GEV + +R+ + E +R G YFGE+AL+ N PR A+ YA+G K +D +++ RLLGPC+D M++N + Y QL K+
Sbjct: 10 LTELLQGYTVEVLRQQPPDLVEFAVEYFTRLREARAPASVLPAATPRQSLGHPPPEPGPDRVADAKGDSESEEDEDLEVPVPSRFNRRVSVCAETYNPDEEEEDT--DPRVIHPKTDEQRCRLQEACKDILLFKNLDQEQLSQVLDAMFE-RIVKADEHVIDQGDDGDNFYVIERGTYDILVTKDNQTRSVGQ-YDNRGSFGELALMYNTPRAATIVATSEGSLWGLDRVTFRRIIVKNNAKKRKMFESFIESVPLLKSLEVSERMKIVDVIGEKIYKDGERIITQGEKADSFYIIESGEVSILIRSRTKSNKDGGNQEVEIARCHKGQYFGELALVTNKPRAASAYAVGDVKCLVMDVQAFERLLGPCMDIMKRNISHYEEQLVKMFG 394
BLAST of cAMP-dependent protein kinase type II regulatory subunit vs. Ensembl Human
Match: PRKAR2A (protein kinase cAMP-dependent type II regulatory subunit alpha [Source:HGNC Symbol;Acc:HGNC:9391]) HSP 1 Score: 213.386 bits (542), Expect = 3.195e-64 Identity = 134/389 (34.45%), Postives = 223/389 (57.33%), Query Frame = 1
Query: 97 LTEVIEEFKKQVEIANPKDIIAYAATYFTK-KVAQENES--NDTEFDKSLDYDSSSEDGDSLKEIMSNDKSKMKLVQTSNVP-----RQSITCESFDPSSIDDETFEKNRKIYPKTPKQMDKITDILETIFFFNCLDEIQFSKIIQSMFFIEVFKGDE-IIKENDPGNNFYVIDYGTF----TASNKSKSIYEVYKGEGFFGELALLYNCPRSASVIADTDGGLWVIDRVTFRQLILKSAYQKRQRYLKFISSVPLLEDLTKYEQCNLADALKTKTI-NNEKVISQGDAGDKMYFIXXXXXXXXXXXXXXX--------XXXSRLKAGDYFGEVALLANIPRIANVYALGYTKLAELDAKSYTRLLGPCIDNMRKNFTKYRSQLEKLLS 1197
LTE+++ + +V P D++ +A YFT+ + A+ S +SL + D + + + +S+ VP R S+ E+++P +++T R I+PKT +Q ++ + + I F LD+ Q S+++ +MF + K DE +I + D G+NFYVI+ GT+ T N+++S+ + Y G FGELAL+YN PR+A+++A ++G LW +DRVTFR++I+K+ +KR+ + FI SVPLL+ L E+ + D + K + E++I+QG+ D Y IE GEV + +R+ + E +R G YFGE+AL+ N PR A+ YA+G K +D +++ RLLGPC+D M++N + Y QL K+
Sbjct: 10 LTELLQGYTVEVLRQQPPDLVEFAVEYFTRLREARAPASVLPAATPRQSLGHPPPEPGPDRVADAKGDSESEEDEDLEVPVPSRFNRRVSVCAETYNPDEEEEDT--DPRVIHPKTDEQRCRLQEACKDILLFKNLDQEQLSQVLDAMFE-RIVKADEHVIDQGDDGDNFYVIERGTYDILVTKDNQTRSVGQ-YDNRGSFGELALMYNTPRAATIVATSEGSLWGLDRVTFRRIIVKNNAKKRKMFESFIESVPLLKSLEVSERMKIVDVIGEKIYKDGERIITQGEKADSFYIIESGEVSILIRSRTKSNKDGGNQEVEIARCHKGQYFGELALVTNKPRAASAYAVGDVKCLVMDVQAFERLLGPCMDIMKRNISHYEEQLVKMFG 394
BLAST of cAMP-dependent protein kinase type II regulatory subunit vs. Ensembl Human
Match: PRKAR2A (protein kinase cAMP-dependent type II regulatory subunit alpha [Source:HGNC Symbol;Acc:HGNC:9391]) HSP 1 Score: 206.068 bits (523), Expect = 1.281e-61 Identity = 127/385 (32.99%), Postives = 213/385 (55.32%), Query Frame = 1
Query: 97 LTEVIEEFKKQVEIANPKDIIAYAATYFTK-KVAQENES--NDTEFDKSLDYDSSSEDGDSLKEIMSNDKSKMKLVQTSNVP-----RQSITCESFDPSSIDDETFEKNRKIYPKTPKQMDKITDILETIFFFNCLDEIQFSKIIQSMFFIEVFKGDE-IIKENDPGNNFYVIDYGTF----TASNKSKSIYEVYKGEGFFGELALLYNCPRSASVIADTDGGLWVIDRVTFRQLILKSAYQKRQRYLKFISSVPLLEDLTKYEQCNLADALKTKTI-NNEKVISQG----DAGDKMYFIXXXXXXXXXXXXXXXXXXSRLKAGDYFGEVALLANIPRIANVYALGYTKLAELDAKSYTRLLGPCIDNMRKNFTKYRSQLEKLLS 1197
LTE+++ + +V P D++ +A YFT+ + A+ S +SL + D + + + +S+ VP R S+ E+++P +++T R I+PKT +Q ++ + + I F LD+ Q S+++ +MF + K DE +I + D G+NFYVI+ GT+ T N+++S+ + Y G FGELAL+YN PR+A+++A ++G LW +DRVTFR++I+K+ +KR+ + FI SVPLL+ L E+ + D + K + E++I+Q D G++ I +R G YFGE+AL+ N PR A+ YA+G K +D +++ RLLGPC+D M++N + Y QL K+
Sbjct: 10 LTELLQGYTVEVLRQQPPDLVEFAVEYFTRLREARAPASVLPAATPRQSLGHPPPEPGPDRVADAKGDSESEEDEDLEVPVPSRFNRRVSVCAETYNPDEEEEDT--DPRVIHPKTDEQRCRLQEACKDILLFKNLDQEQLSQVLDAMFE-RIVKADEHVIDQGDDGDNFYVIERGTYDILVTKDNQTRSVGQ-YDNRGSFGELALMYNTPRAATIVATSEGSLWGLDRVTFRRIIVKNNAKKRKMFESFIESVPLLKSLEVSERMKIVDVIGEKIYKDGERIITQTKSNKDGGNQEVEI------------------ARCHKGQYFGELALVTNKPRAASAYAVGDVKCLVMDVQAFERLLGPCMDIMKRNISHYEEQLVKMFG 372
BLAST of cAMP-dependent protein kinase type II regulatory subunit vs. Ensembl Celegans
Match: kin-2 (cAMP-dependent protein kinase regulatory subunit [Source:UniProtKB/Swiss-Prot;Acc:P30625]) HSP 1 Score: 159.458 bits (402), Expect = 6.943e-45 Identity = 98/280 (35.00%), Postives = 156/280 (55.71%), Query Frame = 1
Query: 346 TCESFDPSSIDDETFEKNRKIYPKTPKQMDKITDILETIFFFNCLDEIQFSKIIQSMFFIEVFKGDEIIKENDPGNNFYVIDYGTFTASNKSKSIYEVYKGEGFFGELALLYNCPRSASVIADTDGGLWVIDRVTFRQLILKSAYQKRQRYLKFISSVPLLEDLTKYEQCNLADALKTKTIN-NEKVISQGDAGDKMYFIXXXXXXXXXXXXXXXX--XXSRLKAGDYFGEVALLANIPRIANVYALGYTKLAELDAKSYTRLLGPCIDNMRKNFTKYRS 1176
T S +P DD ++K + PK + + F L+E + + +MF +E G+ II++ + G+NFYVID GT + + + +G G FGELAL+Y PR+A+VIA TD LW IDR+T+R++++ S +KR+ Y +F+S V +L DL ++E+ N+ADAL+ V+ QG GD+ + I EGE V + ++ L DYFGE+ALL + PR A V A + K +LD + R++GP + ++++ + Y S
Sbjct: 52 TGISAEPIKEDDTEYKK--VVIPKDDATRRSLESAMRKNLLFAHLEEDEQKTMYDAMFPVEKSAGETIIEQGEEGDNFYVIDKGTVDVYVNHEYVLTINEG-GSFGELALIYGTPRAATVIAKTDVKLWAIDRLTYRRILMGSVTKKRKMYDEFLSKVQILADLDQWERANVADALERCDFEPGTHVVEQGQPGDEFFIILEGEANVLQKRSDDAPFDVVGHLGMSDYFGEIALLLDRPRAATVVAKTHLKCIKLDRNRFERVMGPVREILKRDVSNYNS 328
BLAST of cAMP-dependent protein kinase type II regulatory subunit vs. Ensembl Celegans
Match: kin-2 (cAMP-dependent protein kinase regulatory subunit [Source:UniProtKB/Swiss-Prot;Acc:P30625]) HSP 1 Score: 159.844 bits (403), Expect = 1.120e-44 Identity = 97/277 (35.02%), Postives = 155/277 (55.96%), Query Frame = 1
Query: 355 SFDPSSIDDETFEKNRKIYPKTPKQMDKITDILETIFFFNCLDEIQFSKIIQSMFFIEVFKGDEIIKENDPGNNFYVIDYGTFTASNKSKSIYEVYKGEGFFGELALLYNCPRSASVIADTDGGLWVIDRVTFRQLILKSAYQKRQRYLKFISSVPLLEDLTKYEQCNLADALKTKTIN-NEKVISQGDAGDKMYFIXXXXXXXXXXXXXXXX--XXSRLKAGDYFGEVALLANIPRIANVYALGYTKLAELDAKSYTRLLGPCIDNMRKNFTKYRS 1176
S +P DD ++K + PK + + F L+E + + +MF +E G+ II++ + G+NFYVID GT + + + +G G FGELAL+Y PR+A+VIA TD LW IDR+T+R++++ S +KR+ Y +F+S V +L DL ++E+ N+ADAL+ V+ QG GD+ + I EGE V + ++ L DYFGE+ALL + PR A V A + K +LD + R++GP + ++++ + Y S
Sbjct: 87 SAEPIKEDDTEYKK--VVIPKDDATRRSLESAMRKNLLFAHLEEDEQKTMYDAMFPVEKSAGETIIEQGEEGDNFYVIDKGTVDVYVNHEYVLTINEG-GSFGELALIYGTPRAATVIAKTDVKLWAIDRLTYRRILMGSVTKKRKMYDEFLSKVQILADLDQWERANVADALERCDFEPGTHVVEQGQPGDEFFIILEGEANVLQKRSDDAPFDVVGHLGMSDYFGEIALLLDRPRAATVVAKTHLKCIKLDRNRFERVMGPVREILKRDVSNYNS 360
BLAST of cAMP-dependent protein kinase type II regulatory subunit vs. Ensembl Celegans
Match: kin-2 (cAMP-dependent protein kinase regulatory subunit [Source:UniProtKB/Swiss-Prot;Acc:P30625]) HSP 1 Score: 159.458 bits (402), Expect = 1.586e-44 Identity = 97/277 (35.02%), Postives = 155/277 (55.96%), Query Frame = 1
Query: 355 SFDPSSIDDETFEKNRKIYPKTPKQMDKITDILETIFFFNCLDEIQFSKIIQSMFFIEVFKGDEIIKENDPGNNFYVIDYGTFTASNKSKSIYEVYKGEGFFGELALLYNCPRSASVIADTDGGLWVIDRVTFRQLILKSAYQKRQRYLKFISSVPLLEDLTKYEQCNLADALKTKTIN-NEKVISQGDAGDKMYFIXXXXXXXXXXXXXXXX--XXSRLKAGDYFGEVALLANIPRIANVYALGYTKLAELDAKSYTRLLGPCIDNMRKNFTKYRS 1176
S +P DD ++K + PK + + F L+E + + +MF +E G+ II++ + G+NFYVID GT + + + +G G FGELAL+Y PR+A+VIA TD LW IDR+T+R++++ S +KR+ Y +F+S V +L DL ++E+ N+ADAL+ V+ QG GD+ + I EGE V + ++ L DYFGE+ALL + PR A V A + K +LD + R++GP + ++++ + Y S
Sbjct: 97 SAEPIKEDDTEYKK--VVIPKDDATRRSLESAMRKNLLFAHLEEDEQKTMYDAMFPVEKSAGETIIEQGEEGDNFYVIDKGTVDVYVNHEYVLTINEG-GSFGELALIYGTPRAATVIAKTDVKLWAIDRLTYRRILMGSVTKKRKMYDEFLSKVQILADLDQWERANVADALERCDFEPGTHVVEQGQPGDEFFIILEGEANVLQKRSDDAPFDVVGHLGMSDYFGEIALLLDRPRAATVVAKTHLKCIKLDRNRFERVMGPVREILKRDVSNYNS 370
BLAST of cAMP-dependent protein kinase type II regulatory subunit vs. Ensembl Celegans
Match: egl-4 (cGMP-dependent protein kinase egl-4 [Source:UniProtKB/Swiss-Prot;Acc:O76360]) HSP 1 Score: 109.768 bits (273), Expect = 1.914e-25 Identity = 80/297 (26.94%), Postives = 149/297 (50.17%), Query Frame = 1
Query: 283 MSNDKSKMKLVQTSNVPRQSITCESFDPSSIDDETFEKNRKIYPKTPKQMDKITDILETIFFFNCLDEIQFSKIIQSMFFIEVFKGDEIIKENDPGNNFYVIDYGTFTASNKSKSIYEVYKGEGFFGELALLYNCPRSASVIADTDGGLWVIDRVTFRQLILKSAYQKRQRYLKFISSVPLLEDLTKYEQCNLADALKTKTINNEK-VISQGDAGDKMYFIXXXXXXXXXXXXXXXXXXS--RLKAGDYFGEVALLANIPRIANVYALG-YTKLAELDAKSYTRLLGPCIDNMRKNF 1161
+ ND + ++ V R S +P++ +++ + Y KT I D ++ F L + Q +++ M+ + G +I+E +PG+ +V+ G S + + ++ G GELA+LYNC R+ASV A TD LWV+DR F+ + + ++ + + F++ V + ++L++ +AD + + +I QG+ GD + I G+V VT + E L GD+FGE ALL R AN+ A ++ LD +S+ +L+G +++++K++
Sbjct: 111 LGNDLQQKAVLPADGVQRAKKIAVSAEPTNFENKP--ATLQHYNKTVGAKQMIRDAVQKNDFLKQLAKEQIIELVNCMYEMRARAGQWVIQEGEPGDRLFVVAEGELQVSREGALLGKMRAGT-VMGELAILYNCTRTASVQALTDVQLWVLDRSVFQMITQRLGMERHSQLMNFLTKVSIFQNLSEDRISKMADVMDQDYYDGGHYIIRQGEKGDAFFVINSGQVKVTQQIEGETEPREIRVLNQGDFFGERALLGEEVRTANIIAQAPGVEVLTLDRESFGKLIGD-LESLKKDY 403
BLAST of cAMP-dependent protein kinase type II regulatory subunit vs. Ensembl Celegans
Match: egl-4 (cGMP-dependent protein kinase egl-4 [Source:UniProtKB/Swiss-Prot;Acc:O76360]) HSP 1 Score: 109.768 bits (273), Expect = 1.914e-25 Identity = 80/297 (26.94%), Postives = 149/297 (50.17%), Query Frame = 1
Query: 283 MSNDKSKMKLVQTSNVPRQSITCESFDPSSIDDETFEKNRKIYPKTPKQMDKITDILETIFFFNCLDEIQFSKIIQSMFFIEVFKGDEIIKENDPGNNFYVIDYGTFTASNKSKSIYEVYKGEGFFGELALLYNCPRSASVIADTDGGLWVIDRVTFRQLILKSAYQKRQRYLKFISSVPLLEDLTKYEQCNLADALKTKTINNEK-VISQGDAGDKMYFIXXXXXXXXXXXXXXXXXXS--RLKAGDYFGEVALLANIPRIANVYALG-YTKLAELDAKSYTRLLGPCIDNMRKNF 1161
+ ND + ++ V R S +P++ +++ + Y KT I D ++ F L + Q +++ M+ + G +I+E +PG+ +V+ G S + + ++ G GELA+LYNC R+ASV A TD LWV+DR F+ + + ++ + + F++ V + ++L++ +AD + + +I QG+ GD + I G+V VT + E L GD+FGE ALL R AN+ A ++ LD +S+ +L+G +++++K++
Sbjct: 111 LGNDLQQKAVLPADGVQRAKKIAVSAEPTNFENKP--ATLQHYNKTVGAKQMIRDAVQKNDFLKQLAKEQIIELVNCMYEMRARAGQWVIQEGEPGDRLFVVAEGELQVSREGALLGKMRAGT-VMGELAILYNCTRTASVQALTDVQLWVLDRSVFQMITQRLGMERHSQLMNFLTKVSIFQNLSEDRISKMADVMDQDYYDGGHYIIRQGEKGDAFFVINSGQVKVTQQIEGETEPREIRVLNQGDFFGERALLGEEVRTANIIAQAPGVEVLTLDRESFGKLIGD-LESLKKDY 403
BLAST of cAMP-dependent protein kinase type II regulatory subunit vs. Ensembl Fly
Match: Pka-R2 (gene:FBgn0022382 transcript:FBtr0088437) HSP 1 Score: 258.07 bits (658), Expect = 3.847e-82 Identity = 148/369 (40.11%), Postives = 226/369 (61.25%), Query Frame = 1
Query: 97 LTEVIEEFKKQVEIANPKDIIAYAATYFTKKVAQENESNDTEFDKSLDYDSSSEDGDSLKEIMSNDKSKMKLVQTSNVPRQSITCESFDPSSIDDETFEKNRKIYPKTPKQMDKITDILETIFFFNCLDEIQFSKIIQSMFFIEVFKGDEIIKENDPGNNFYVIDYGTFTASNKSKSIYEVYKGEGFFGELALLYNCPRSASVIADTDGGLWVIDRVTFRQLILKSAYQKRQRYLKFISSVPLLEDLTKYEQCNLADALKTKTINN-EKVISQGDAGDKMYFIXXXXXXXXXXXXXXXXXXSRLKAGDYFGEVALLANIPRIANVYAL-GYTKLAELDAKSYTRLLGPCIDNMRKNFTKYRSQLEKLLS 1197
L EV+ +F + P D+I YA YFTK ++ + T+ +S+D D+ +M++ + R+S+ E++DP + + + ++PKT +Q ++ + ++ + F L++ Q ++++ +MF +V GD II++ D G+NFYVI+ G + K I Y G FGELALLYN PR+A+V A+T G LW +DR TFR+++LKSA++KR+ Y + ++SVP+L+ L YE+ NLADAL +K+ +N E++I QGDA D MYFIEEG V V + + E E S+L G YFGE+AL+ + PR A+VYA G KLA LD K++ RLLGPC+D M++N Y SQL K+
Sbjct: 15 LKEVLLQFSISFLVEQPPDVIDYAVEYFTKLQSERPSVSHTDQSTDDQLSVNSQDADAEPPVMASSR------------RKSVFAEAYDPEAD--DDDDGATAVFPKTDEQRARLVESVKNVLLFRSLEKEQMNQVLDAMFERKVQPGDFIIRQGDDGDNFYVIESGVYKVYINDKHI-NTYNHTGLFGELALLYNMPRAATVQAETSGLLWAMDRQTFRRILLKSAFRKRKMYEELLNSVPMLKALQNYERMNLADALVSKSYDNGERIIKQGDAADGMYFIEEGTVSVRMDQDDAEVEISQLGKGQYFGELALVTHRPRAASVYATGGVVKLAFLDVKAFERLLGPCMDIMKRNIDDYESQLVKIFG 368
BLAST of cAMP-dependent protein kinase type II regulatory subunit vs. Ensembl Fly
Match: Pka-R2 (gene:FBgn0022382 transcript:FBtr0088438) HSP 1 Score: 258.07 bits (658), Expect = 3.847e-82 Identity = 148/369 (40.11%), Postives = 226/369 (61.25%), Query Frame = 1
Query: 97 LTEVIEEFKKQVEIANPKDIIAYAATYFTKKVAQENESNDTEFDKSLDYDSSSEDGDSLKEIMSNDKSKMKLVQTSNVPRQSITCESFDPSSIDDETFEKNRKIYPKTPKQMDKITDILETIFFFNCLDEIQFSKIIQSMFFIEVFKGDEIIKENDPGNNFYVIDYGTFTASNKSKSIYEVYKGEGFFGELALLYNCPRSASVIADTDGGLWVIDRVTFRQLILKSAYQKRQRYLKFISSVPLLEDLTKYEQCNLADALKTKTINN-EKVISQGDAGDKMYFIXXXXXXXXXXXXXXXXXXSRLKAGDYFGEVALLANIPRIANVYAL-GYTKLAELDAKSYTRLLGPCIDNMRKNFTKYRSQLEKLLS 1197
L EV+ +F + P D+I YA YFTK ++ + T+ +S+D D+ +M++ + R+S+ E++DP + + + ++PKT +Q ++ + ++ + F L++ Q ++++ +MF +V GD II++ D G+NFYVI+ G + K I Y G FGELALLYN PR+A+V A+T G LW +DR TFR+++LKSA++KR+ Y + ++SVP+L+ L YE+ NLADAL +K+ +N E++I QGDA D MYFIEEG V V + + E E S+L G YFGE+AL+ + PR A+VYA G KLA LD K++ RLLGPC+D M++N Y SQL K+
Sbjct: 15 LKEVLLQFSISFLVEQPPDVIDYAVEYFTKLQSERPSVSHTDQSTDDQLSVNSQDADAEPPVMASSR------------RKSVFAEAYDPEAD--DDDDGATAVFPKTDEQRARLVESVKNVLLFRSLEKEQMNQVLDAMFERKVQPGDFIIRQGDDGDNFYVIESGVYKVYINDKHI-NTYNHTGLFGELALLYNMPRAATVQAETSGLLWAMDRQTFRRILLKSAFRKRKMYEELLNSVPMLKALQNYERMNLADALVSKSYDNGERIIKQGDAADGMYFIEEGTVSVRMDQDDAEVEISQLGKGQYFGELALVTHRPRAASVYATGGVVKLAFLDVKAFERLLGPCMDIMKRNIDDYESQLVKIFG 368
BLAST of cAMP-dependent protein kinase type II regulatory subunit vs. Ensembl Fly
Match: Pka-R2 (gene:FBgn0022382 transcript:FBtr0112902) HSP 1 Score: 239.195 bits (609), Expect = 9.363e-75 Identity = 139/361 (38.50%), Postives = 218/361 (60.39%), Query Frame = 1
Query: 97 LTEVIEEFKKQVEIANPKDIIAYAATYFTKKVAQENESNDTEFDKSLDYDSSSEDGDSLKEIMSNDKSKMKLVQTSNVPRQSITCESFDPSSIDDETFEKNRKIYPKTPKQMDKITDILETIFFFNCLDEIQFSKIIQSMFFIEVFKGDEIIKENDPGNNFYVIDYGTFTASNKSKSIYEVYKGEGFFGELALLYNCPRSASVIADTDGGLWVIDRVTFRQLILKSAYQKRQRYLKFISSVPLLEDLTKYEQCNLADALKTKTINN-EKVISQGDAGDKMYFIXXXXXXXXXXXXXXXXXXSRLKAGDYFGEVALLANIPRIANVYAL-GYTKLAELDAKSYTRLLGPCIDNMRKNFTKYR 1173
L EV+ +F + P D+I YA YFTK ++ + T+ +S+D D+ +M++ + R+S+ E++DP + + + ++PKT +Q ++ + ++ + F L++ Q ++++ +MF +V GD II++ D G+NFYVI+ G + K I Y G FGELALLYN PR+A+V A+T G LW +DR TFR+++LKSA++KR+ Y + ++SVP+L+ L YE+ NLADAL +K+ +N E++I QGDA D MYFIEEG V V + + E E S+L G YFGE+AL+ + PR A+VYA G KLA LD + RL+G C ++++ + YR
Sbjct: 15 LKEVLLQFSISFLVEQPPDVIDYAVEYFTKLQSERPSVSHTDQSTDDQLSVNSQDADAEPPVMASSR------------RKSVFAEAYDPEAD--DDDDGATAVFPKTDEQRARLVESVKNVLLFRSLEKEQMNQVLDAMFERKVQPGDFIIRQGDDGDNFYVIESGVYKVYINDKHI-NTYNHTGLFGELALLYNMPRAATVQAETSGLLWAMDRQTFRRILLKSAFRKRKMYEELLNSVPMLKALQNYERMNLADALVSKSYDNGERIIKQGDAADGMYFIEEGTVSVRMDQDDAEVEISQLGKGQYFGELALVTHRPRAASVYATGGVVKLAFLDVICFERLMGKCSGGIQRSISGYR 360
BLAST of cAMP-dependent protein kinase type II regulatory subunit vs. Ensembl Fly
Match: Pka-R2 (gene:FBgn0022382 transcript:FBtr0112901) HSP 1 Score: 238.424 bits (607), Expect = 1.391e-74 Identity = 143/373 (38.34%), Postives = 223/373 (59.79%), Query Frame = 1
Query: 97 LTEVIEEFKKQVEIANPKDIIAYAATYFTKKVAQENESNDTEFDKSLDYDSS--SEDGDSLKEIMSNDKSKMKLVQTSNVPRQSITCESFDPSSIDDETFEKNRKIYPKTPKQMDKITDILETIFFFNCLDEIQFSKIIQSMFFIEVFKGDEIIKENDPGNNFYVIDYGTFTASNKSKSIYEVYKGEGFFGELALLYNCPRSASVIADTDGGLWVIDRVTFRQLILKSAYQKRQRYLKFISSVPLLEDLTKYEQCNLADALKTKTINN-EKVISQGDAGDKMYFIXXXXXXXXXXXXXXXXXXSRLKAGDYFGEVALLANIPRIANVYAL-GYTKLAELDAKSYTRLLGPCIDNMRKNFTKYRSQLEKLLSRH 1203
L EV+ +F + P D+I YA YFTK Q + + D+S D S S+D D+ +M++ + R+S+ E++DP + + + ++PKT +Q ++ + ++ + F L++ Q ++++ +MF +V GD II++ D G+NFYVI+ G + K I Y G FGELALLYN PR+A+V A+T G LW +DR TFR+++LKSA++KR+ Y + ++SVP+L+ L YE+ NLADAL +K+ +N E++I QGDA D MYFIEEG V V + + E E S+L G YFGE+AL+ + PR A+VYA G KLA LD +++ R++G D +++N Y + R+
Sbjct: 15 LKEVLLQFSISFLVEQPPDVIDYAVEYFTK--LQSERPSVSHTDQSTDDQLSVNSQDADAEPPVMASSR------------RKSVFAEAYDPEAD--DDDDGATAVFPKTDEQRARLVESVKNVLLFRSLEKEQMNQVLDAMFERKVQPGDFIIRQGDDGDNFYVIESGVYKVYINDKHI-NTYNHTGLFGELALLYNMPRAATVQAETSGLLWAMDRQTFRRILLKSAFRKRKMYEELLNSVPMLKALQNYERMNLADALVSKSYDNGERIIKQGDAADGMYFIEEGTVSVRMDQDDAEVEISQLGKGQYFGELALVTHRPRAASVYATGGVVKLAFLDTEAFERIMGFLTDVLKRNIVIYEQMFTDMARRN 370
BLAST of cAMP-dependent protein kinase type II regulatory subunit vs. Ensembl Fly
Match: Pka-R1 (gene:FBgn0259243 transcript:FBtr0300532) HSP 1 Score: 188.734 bits (478), Expect = 4.094e-56 Identity = 117/309 (37.86%), Postives = 182/309 (58.90%), Query Frame = 1
Query: 265 DSLKEIMSNDKSK--MKLVQTSNVPRQSITCESFDPSSIDDETFEKNRKIYPKTPKQMDKITDILETIFFFNCLDEIQFSKIIQSMFFIEVFKGDEIIKENDPGNNFYVIDYGTFTASNKSKSIYEVYKGEGFFGELALLYNCPRSASVIADTDGGLWVIDRVTFRQLILKSAYQKRQRYLKFISSVPLLEDLTKYEQCNLADALKTKTINN-EKVISQGDAGDKMYFIXXXXXXXXXXXXXXX--XXXSRLKAGDYFGEVALLANIPRIANVYALGYTKLAELDAKSYTRLLGPCIDNMRKNFTKYRS 1176
D+ ++++S D + + QT+ P + S +P + +D T +K+ PK K M+ ++ + F LDE + S I +MF + G+ II++ D G+NFYVID G S+ + + +G G FGELAL+Y PR+A+V A TD LW IDR ++R++++ S +KR+ Y +F+S V +LE L K+E+ +AD+L+T + ++ E ++ QG AGD Y I EG +V + E E E RL + DYFGE+ALL + PR A V A G K +LD + R+LGPC D +++N T+Y S
Sbjct: 7 DASRQVISPDDCEDLSPMPQTAAPPVRRRGGISAEPVTEEDAT-NYVKKVVPKDYKTMNALSKAIAKNVLFAHLDESERSDIFDAMFPVNHIAGENIIQQGDEGDNFYVIDVGEVDVFVNSELVTTISEG-GSFGELALIYGTPRAATVRAKTDVKLWGIDRDSYRRILMGSTIRKRKMYEEFLSRVSILESLDKWERLTVADSLETCSFDDGETIVKQGAAGDDFYIILEGCAVVLQQRSEGEDPAEVGRLGSSDYFGEIALLLDRPRAATVVARGPLKCVKLDRARFERVLGPCADILKRNITQYNS 313
BLAST of cAMP-dependent protein kinase type II regulatory subunit vs. Ensembl Zebrafish
Match: prkar2aa (protein kinase, cAMP-dependent, regulatory, type II, alpha A [Source:ZFIN;Acc:ZDB-GENE-030131-1007]) HSP 1 Score: 211.46 bits (537), Expect = 9.554e-64 Identity = 130/386 (33.68%), Postives = 201/386 (52.07%), Query Frame = 1
Query: 97 LTEVIEEFKKQVEIANPKDIIAYAATYFTKKVAQENESNDTEFDKSLDYDSSSEDGDSLKEIMSNDKSKMKLVQTSNVP--------RQSITCESFDPSSIDDETFEKNRKIYPKTPKQMDKITDILETIFFFNCLDEIQFSKIIQSMFFIEVFKGDEIIKENDPGNNFYVIDYGTF---TASNKSKSIYEVYKGEGFFGELALLYNCPRSASVIADTDGGLWVIDRVTFRQLILKSAYQKRQRYLKFISSVPLLEDLTKYEQCNLADALKTKTI-NNEKVISQGDAGDKMYF-------IXXXXXXXXXXXXXXXXXXSRLKAGDYFGEVALLANIPRIANVYALGYTKLAELDAKSYTRLLGPCIDNMRKNFTKYRSQLEKLLS 1197
LTE+++ + +V P D++ +A YFT+ ++ K+ DG+ + + SN + + P R S+ E+F+P DDE + R ++PKT +Q ++ + + I F LD+ QFS+++ +MF + V D +I + D G+NFYVI+ G + + Y +G FGELAL+YN PR+A++IA +G LW +DR TFR+LI+K+ +KR+ Y FI S+PLL+ L E+ + D L KT + E++I QGD D Y I R E E +R G YFGE+AL+ N PR A+ YA+G K +D +++ RLLGPC + M++N Y QL L
Sbjct: 9 LTELLQGYTVEVLRQRPPDLVEFAVQYFTRLRDTRSQDGSGAAAKT-GGKGVMFDGEPM-QTESNGDEDDEDDDSDFEPPPPSRFNRRVSVCAEAFNPD--DDEEDSEPRVVHPKTDEQRCRLQEACKDILLFKALDQEQFSEVLDAMFEVLVQPQDHVIDQGDDGDNFYVIERGVYDIVVQKDGVGCCVGQYNNKGSFGELALMYNTPRAATIIAKDEGALWGLDRATFRRLIVKNNAKKRRMYECFIESIPLLKSLELSERMKIVDVLGVKTFQDGERIIMQGDKADCFYIVESGEVKIMMKSKTKADRQDNAEVEIARCSRGQYFGELALVTNKPRAASAYAIGDVKCLVIDIQAFERLLGPCKEIMKRNIAHYEEQLVALFG 390
BLAST of cAMP-dependent protein kinase type II regulatory subunit vs. Ensembl Zebrafish
Match: PRKAR2B (si:ch211-272n13.7 [Source:ZFIN;Acc:ZDB-GENE-160113-22]) HSP 1 Score: 207.223 bits (526), Expect = 3.392e-62 Identity = 129/387 (33.33%), Postives = 206/387 (53.23%), Query Frame = 1
Query: 97 LTEVIEEFKKQVEIANPKDIIAYAATYFTKKVAQENESNDTEFD----------KSLDY-----DSSSEDGDSLKEIMSNDKSKMKLVQTSNVPRQSITCESFDPSSIDDETFEKNRKIYPKTPKQMDKITDILETIFFFNCLDEIQFSKIIQSMFFIEVFKGDEIIKENDPGNNFYVIDYGTF----TASNKSKSIYEVYKGEGFFGELALLYNCPRSASVIADTDGGLWVIDRVTFRQLILKSAYQKRQRYLKFISSVPLLEDLTKYEQCNLADALKTKTIN-NEKVISQGDAGDKMYFIXXXXXXXXXXXXXXXXXXSRLKAGDYFGEVALLANIPRIANVYALGYTKLAELDAKSYTRLLGPCIDNMRKNFTKYRSQLEKLLS 1197
LTE+++ F +V P D++ +A YFT+ +ENE+ F K++++ SE+G+ + + + + P+ C YPKT +Q ++ + + I F LD+ Q S+++ +MF V G+ II ++D G+NFYVI+ G F A ++++ Y G FGELAL+YN PR+A++IA + G LW +DR+TFR++I+K+ +KR+ Y FI ++PLL L E+ + D L TK N E++I+QGD D Y +E G V +T++ + E E + G YFGE+AL+ N PR A+ YA+ K +D +++ RLLGPC+D M++N Y QL L
Sbjct: 9 LTELLQSFTVEVLRNQPADLLEFALQYFTR--LKENETRGGAFGNERNPATRAGKAVNFIEEAMQIDSENGEEEDDDEEFVDAAFAQLLLAGFPQCFAVCAQV---------------TYPKTDEQRQRLQEACKDILLFKNLDQEQMSQVLDAMFEKVVVSGEHIIDQDDDGDNFYVIERGMFEILLKADGTTRTVGS-YDNRGSFGELALMYNTPRAATIIATSPGALWCLDRLTFRRIIVKNNAKKRKMYEAFIGTLPLLTSLEVSERMKVVDVLSTKVYNGGEQIIAQGDLADCFYIVESGHVRITMKRSKVEVEIATCSRGQYFGELALVTNKPRAASAYAMDSVKCLVMDVQAFERLLGPCMDIMKRNIANYEEQLITLFG 377
BLAST of cAMP-dependent protein kinase type II regulatory subunit vs. Ensembl Zebrafish
Match: PRKAR2B (si:ch211-272n13.7 [Source:ZFIN;Acc:ZDB-GENE-160113-22]) HSP 1 Score: 205.682 bits (522), Expect = 9.711e-62 Identity = 132/384 (34.38%), Postives = 212/384 (55.21%), Query Frame = 1
Query: 97 LTEVIEEFKKQVEIANPKDIIAYAATYFTKKVAQENESNDTEFDKSLDYDSSSEDGDSLKEIMSNDKSKMKLVQ-----TSNVPRQSITCESFDPSSIDDETFEKNRKIYPKTPKQMDKITDILETIFFFNCLDEIQFSKIIQSMFFIEVFKGDEIIKENDPGNNFYVIDYGTF----TASNKSKSIYEVYKGEGFFGELALLYNCPRSASVIADTDGGLWVIDRVTFRQLILKSAYQKRQRYLKFISSVPLLEDLTKYEQCNLADALKTKTIN-NEKVISQGDAGDKMYFIXXXXXXXXXXXXXXXXXXSRLKAGDYFGEVALLANIPRIANVYALGYTKLAELDAKSYTRLLGPCIDNMRKNFTKYRSQLEKLL-SRHQLEE 1215
LTE+++ F +V P D++ +A YFT+ +ENE+ F +E + ++E M D + N ++ E+++P ++E + R YPKT +Q ++ + + I F LD+ Q S+++ +MF V G+ II ++D G+NFYVI+ G F A ++++ Y G FGELAL+YN PR+A++IA + G LW +DR+TFR++I+K+ +KR+ Y FI ++PLL L E+ + D L TK N E++I+QGD D ++I E + +E E + G YFGE+AL+ N PR A+ YA+ K +D +++ RLLGPC+D M++N Y QL L S+ +EE
Sbjct: 9 LTELLQSFTVEVLRNQPADLLEFALQYFTR--LKENETRGGAF--------GNEPVNFIEEAMQIDSENGEEEDDDEEFVGNAFASALCAEAYNPDEDEEER--EPRVTYPKTDEQRQRLQEACKDILLFKNLDQEQMSQVLDAMFEKVVVSGEHIIDQDDDGDNFYVIERGMFEILLKADGTTRTVGS-YDNRGSFGELALMYNTPRAATIIATSPGALWCLDRLTFRRIIVKNNAKKRKMYEAFIGTLPLLTSLEVSERMKVVDVLSTKVYNGGEQIIAQGDLAD-CFYIVESGHVRITMKRSKEVEIATCSRGQYFGELALVTNKPRAASAYAMDSVKCLVMDVQAFERLLGPCMDIMKRNIANYEEQLITLFGSQIAIEE 378
BLAST of cAMP-dependent protein kinase type II regulatory subunit vs. Ensembl Zebrafish
Match: PRKAR2B (si:ch211-272n13.7 [Source:ZFIN;Acc:ZDB-GENE-160113-22]) HSP 1 Score: 202.986 bits (515), Expect = 1.962e-60 Identity = 132/387 (34.11%), Postives = 214/387 (55.30%), Query Frame = 1
Query: 97 LTEVIEEFKKQVEIANPKDIIAYAATYFTKKVAQENESNDTEFDKSLDYDSSSEDGDS---LKEIMSNDKSKMKLVQ-----TSNVPRQSITCESFDPSSIDDETFEKNRKIYPKTPKQMDKITDILETIFFFNCLDEIQFSKIIQSMFFIEVFKGDEIIKENDPGNNFYVIDYGTF----TASNKSKSIYEVYKGEGFFGELALLYNCPRSASVIADTDGGLWVIDRVTFRQLILKSAYQKRQRYLKFISSVPLLEDLTKYEQCNLADALKTKTIN-NEKVISQGDAGDKMYFIXXXXXXXXXXXXXX-------XXXXSRLKAGDYFGEVALLANIPRIANVYALGYTKLAELDAKSYTRLLGPCIDNMRKNFTKYRSQLEKLLS 1197
LTE+++ F +V P D++ +A YFT+ +ENE+ F + + ++ G + ++E M D + N ++ E+++P ++E + R YPKT +Q ++ + + I F LD+ Q S+++ +MF V G+ II ++D G+NFYVI+ G F A ++++ Y G FGELAL+YN PR+A++IA + G LW +DR+TFR++I+K+ +KR+ Y FI ++PLL L E+ + D L TK N E++I+QGD D Y +E G V +T++ + E E + G YFGE+AL+ N PR A+ YA+ K +D +++ RLLGPC+D M++N Y QL L
Sbjct: 9 LTELLQSFTVEVLRNQPADLLEFALQYFTR--LKENETRGGAFGN--ERNPATRAGKAVNFIEEAMQIDSENGEEEDDDEEFVGNAFASALCAEAYNPDEDEEER--EPRVTYPKTDEQRQRLQEACKDILLFKNLDQEQMSQVLDAMFEKVVVSGEHIIDQDDDGDNFYVIERGMFEILLKADGTTRTVGS-YDNRGSFGELALMYNTPRAATIIATSPGALWCLDRLTFRRIIVKNNAKKRKMYEAFIGTLPLLTSLEVSERMKVVDVLSTKVYNGGEQIIAQGDLADCFYIVESGHVRITMKRSKSKNDTEDEEVEIATCSRGQYFGELALVTNKPRAASAYAMDSVKCLVMDVQAFERLLGPCMDIMKRNIANYEEQLITLFG 388
BLAST of cAMP-dependent protein kinase type II regulatory subunit vs. Ensembl Zebrafish
Match: prkar2ab (protein kinase, cAMP-dependent, regulatory, type II, alpha, B [Source:ZFIN;Acc:ZDB-GENE-040426-2427]) HSP 1 Score: 181.415 bits (459), Expect = 4.288e-52 Identity = 106/296 (35.81%), Postives = 168/296 (56.76%), Query Frame = 1
Query: 334 RQSITCESFDPSSIDDETFEKNR--KIYPKTPKQMDKITDILETIFFFNCLDEIQFSKIIQSMFFIEVFKGDEIIKENDPGNNFYVIDYGTFTASNKSKSIYEV---YKGEGFFGELALLYNCPRSASVIADTDGGLWVIDRVTFRQLILKSAYQKRQRYLKFISSVPLLEDLTKYEQCNLADALKTKTINN-EKVISQGDAGDKMYF-------IXXXXXXXXXXXXXXXXXXSRLKAGDYFGEVALLANIPRIANVYALGYTKLAELDAKSYTRLLGPCIDNMRKNFTKYRSQL 1182
R S+ E ++P DD+ E ++ ++ KT +Q ++ D + I F L+E Q ++++ SMF + V G+ II + D G+NFYVI+ G + + + Y +G FGELAL+YN PR+A++ A +G LW +DR TF +LI+K+ +KR+ Y FI VPLL+ L E+ + D L ++ ++ E++I QGD+ D Y I + +EE E +R G YFGE+AL+ PR A+VYA+G T+ +D +++ RLLG C +++N T Y QL
Sbjct: 115 RVSVCAEPYNPDEDDDDGDEGSQLTVLHQKTDEQRQRLQDACKHILLFKTLEEDQLAEVLDSMFEVLVKPGECIINQGDDGDNFYVIERGVYEIVIQQDGLQHSVGRYDHKGSFGELALMYNTPRAATIRALQEGALWALDRATFHRLIVKNNAKKRRMYESFIECVPLLKSLQLSERMKIVDVLGMRSFSDGERIIQQGDSADCFYIVESGEVRIMIRSKTRACQLLQEEVEVARCSRGQYFGELALVTKRPRAASVYAVGDTRCLVIDVQAFERLLGSCKQILKRNITHYEQQL 410
BLAST of cAMP-dependent protein kinase type II regulatory subunit vs. Ensembl Xenopus
Match: ednrb2 (endothelin receptor B subtype 2 [Source:Xenbase;Acc:XB-GENE-1219159]) HSP 1 Score: 213.772 bits (543), Expect = 1.463e-64 Identity = 125/379 (32.98%), Postives = 204/379 (53.83%), Query Frame = 1
Query: 97 LTEVIEEFKKQVEIANPKDIIAYAATYFTKKVAQENESNDTEFDKSLDYDSSSEDGDSL-KEIMSNDKSKMKLVQTSNVPRQSITCESFDPSSIDDETFEKNRKIYPKTPKQMDKITDILETIFFFNCLDEIQFSKIIQSMFFIEVFKGDEIIKENDPGNNFYVIDYGTFTASNKSKSIYE---VYKGEGFFGELALLYNCPRSASVIADTDGGLWVIDRVTFRQLILKSAYQKRQRYLKFISSVPLLEDLTKYEQCNLADALKTKT-INNEKVISQGDAGDKMYF-------IXXXXXXXXXXXXXXXXXXSRLKAGDYFGEVALLANIPRIANVYALGYTKLAELDAKSYTRLLGPCIDNMRKNFTKYRSQLEKLLS 1197
LTE+++ F +V P+D++ +A YFT+ ++++S ++ G +E M D + + + + E+++P DD+T + + IYPKT Q +++ + + I F LD+ Q S+++ +MF V G+ +I + D G+NFYVID GT+ KS + Y G FGELAL+YN PR+A+++A + G +W +DR TFR++I+K+ +K++ Y FI S+P L+ L E+ + D + TKT + E++I+QGD D Y I E E +R G YFGE+AL+ N PR A+ YA+G K +D +++ RLLGPC++ M++N Y QL L
Sbjct: 9 LTELLQSFTVEVLRKQPEDLLEFALQYFTQ--LKQSKSQGGPLSHGMELPFRLTKGVIFAEEPMQTDSENGEEEEDDDEEDFVVCAEAYNPDEEDDDT--ETKVIYPKTDDQRNRLQEACKDILLFKSLDQEQMSQVLDAMFEKLVKCGEHVIDQGDDGDNFYVIDRGTYDIFVKSDGVVRCVGAYDNRGSFGELALMYNTPRAATIVATSVGSIWGLDRATFRRIIVKNNAKKKRMYENFIESLPFLKSLEFSERLKVVDVIGTKTYYDGEQIIAQGDGADSFYIVESGEVRINMKSKSKPDAETNEAVEIARYTRGQYFGELALVTNKPRAASAYAVGNVKCLVMDVQAFERLLGPCMEIMKRNIANYEEQLVALFG 383
BLAST of cAMP-dependent protein kinase type II regulatory subunit vs. Ensembl Xenopus
Match: ednrb2 (endothelin receptor B subtype 2 [Source:Xenbase;Acc:XB-GENE-1219159]) HSP 1 Score: 213.001 bits (541), Expect = 4.693e-64 Identity = 128/391 (32.74%), Postives = 208/391 (53.20%), Query Frame = 1
Query: 97 LTEVIEEFKKQVEIANPKDIIAYAATYFTKKVAQENESNDTEFDKSLDY-------------DSSSEDGDSLKEIMSNDKSKMKLVQTSNVPRQSITCESFDPSSIDDETFEKNRKIYPKTPKQMDKITDILETIFFFNCLDEIQFSKIIQSMFFIEVFKGDEIIKENDPGNNFYVIDYGTFTASNKSKSIYE---VYKGEGFFGELALLYNCPRSASVIADTDGGLWVIDRVTFRQLILKSAYQKRQRYLKFISSVPLLEDLTKYEQCNLADALKTKT-INNEKVISQGDAGDKMYF-------IXXXXXXXXXXXXXXXXXXSRLKAGDYFGEVALLANIPRIANVYALGYTKLAELDAKSYTRLLGPCIDNMRKNFTKYRSQLEKLLS 1197
LTE+++ F +V P+D++ +A YFT+ +++ L + + SE+G+ ++ D + + S R S+ E+++P DD+T + + IYPKT Q +++ + + I F LD+ Q S+++ +MF V G+ +I + D G+NFYVID GT+ KS + Y G FGELAL+YN PR+A+++A + G +W +DR TFR++I+K+ +K++ Y FI S+P L+ L E+ + D + TKT + E++I+QGD D Y I E E +R G YFGE+AL+ N PR A+ YA+G K +D +++ RLLGPC++ M++N Y QL L
Sbjct: 9 LTELLQSFTVEVLRKQPEDLLEFALQYFTQLKQSKSQGGPLSHGMELPFRLTKGVIFAEEPMQTDSENGEEEEDDDEEDFVAPVINRFSR--RASVCAEAYNPDEEDDDT--ETKVIYPKTDDQRNRLQEACKDILLFKSLDQEQMSQVLDAMFEKLVKCGEHVIDQGDDGDNFYVIDRGTYDIFVKSDGVVRCVGAYDNRGSFGELALMYNTPRAATIVATSVGSIWGLDRATFRRIIVKNNAKKKRMYENFIESLPFLKSLEFSERLKVVDVIGTKTYYDGEQIIAQGDGADSFYIVESGEVRINMKSKSKPDAETNEAVEIARYTRGQYFGELALVTNKPRAASAYAVGNVKCLVMDVQAFERLLGPCMEIMKRNIANYEEQLVALFG 395
BLAST of cAMP-dependent protein kinase type II regulatory subunit vs. Ensembl Xenopus
Match: fgf1 (fibroblast growth factor 1 [Source:Xenbase;Acc:XB-GENE-485966]) HSP 1 Score: 203.371 bits (516), Expect = 1.781e-60 Identity = 126/390 (32.31%), Postives = 215/390 (55.13%), Query Frame = 1
Query: 97 LTEVIEEFKKQVEIANPKDIIAYAATYFTKKVAQENESNDTEFDKSL-------DYDSSSEDGDSLKEIMSNDKSKMKLVQTSNV-----PRQSITCESFDPSSIDDETFEKNRKIYPKTPKQMDKITDILETIFFFNCLDEIQFSKIIQSMFFIEVFKGDEIIKENDPGNNFYVIDYGT---FTASNKSKSIYEVYKGEGFFGELALLYNCPRSASVIADTDGGLWVIDRVTFRQLILKSAYQKRQRYLKFISSVPLLEDLTKYEQCNLADALKTKTI-NNEKVISQGDAGDKMYFIXXXXXXXXXXXXXXXXXXS-------RLKAGDYFGEVALLANIPRIANVYALGYTKLAELDAKSYTRLLGPCIDNMRKNFTKYRSQLEKLLS 1197
LT++++ + +V P D++ +A YFT+ +E + D SL ++D +S + +++ V R S+ E+++P D++T + R + PKT +Q ++ + + I F LD+ Q S+++ +MF + V + +I + D G+NFYV++ G F + Y G FGELAL+YN PR+A+++A ++G LW +DRVTFR++ILK+ +KR+ Y FI SVP+L+ L E+ + D + + + +++I+QGD D + +E GEV + +++ + +ES R K+G YFGE+AL+ N PR A+ YA+G K +D +++ RLLGPC+D M++N T Y QL L
Sbjct: 9 LTDLLQGYTVEVLRQKPPDLVEFAIQYFTR--LKEKQLQDGAGAGSLRPHARVVNFDGEPMQTESNGDEEEDEEDDDDSDFEPPVINRYSRRVSVCAEAYNPDEEDEDT--EPRVVRPKTDEQRCRLQEACKDILLFKNLDQEQLSQVLDAMFEMRVKPQEHVIDQGDDGDNFYVVERGQYDIFVERDGQSRCVGRYDNHGSFGELALMYNTPRAATIVATSEGALWGLDRVTFRRIILKNNAKKRKTYEIFIESVPVLKFLELSERMKIVDVIAARVYKDGDRIIAQGDKADCFFIVESGEVKIMMKSKTKTGQESNQEVEIARCKSGQYFGELALVTNKPRAASAYAVGDVKCLIMDVQAFERLLGPCMDIMKRNITHYEEQLVALFG 394
BLAST of cAMP-dependent protein kinase type II regulatory subunit vs. Ensembl Xenopus
Match: fgf1 (fibroblast growth factor 1 [Source:Xenbase;Acc:XB-GENE-485966]) HSP 1 Score: 201.06 bits (510), Expect = 1.674e-59 Identity = 125/395 (31.65%), Postives = 214/395 (54.18%), Query Frame = 1
Query: 97 LTEVIEEFKKQVEIANPKDIIAYAATYFTKKVAQENESNDTEFDKSLDYDSS--SEDGDSLK---------------EIMSNDKSKMKLVQTSNVPRQSITCESFDPSSIDDETFEKNRKIYPKTPKQMDKITDILETIFFFNCLDEIQFSKIIQSMFFIEVFKGDEIIKENDPGNNFYVIDYGT---FTASNKSKSIYEVYKGEGFFGELALLYNCPRSASVIADTDGGLWVIDRVTFRQLILKSAYQKRQRYLKFISSVPLLEDLTKYEQCNLADALKTKTI-NNEKVISQGDAGDKMYFIXXXXXXXXXXXXXXXXXXS-------RLKAGDYFGEVALLANIPRIANVYALGYTKLAELDAKSYTRLLGPCIDNMRKNFTKYRSQLEKLLS 1197
LT++++ + +V P D++ +A YFT+ +E + D SL + + DG+ ++ + K L + + E+++P D++T + R + PKT +Q ++ + + I F LD+ Q S+++ +MF + V + +I + D G+NFYV++ G F + Y G FGELAL+YN PR+A+++A ++G LW +DRVTFR++ILK+ +KR+ Y FI SVP+L+ L E+ + D + + + +++I+QGD D + +E GEV + +++ + +ES R K+G YFGE+AL+ N PR A+ YA+G K +D +++ RLLGPC+D M++N T Y QL L
Sbjct: 9 LTDLLQGYTVEVLRQKPPDLVEFAIQYFTR--LKEKQLQDGAGAGSLRPHARVVNFDGEPMQTESNGDEEEDEEDDDDSDFERKRPHVLWAGLEFEKTGVCAEAYNPDEEDEDT--EPRVVRPKTDEQRCRLQEACKDILLFKNLDQEQLSQVLDAMFEMRVKPQEHVIDQGDDGDNFYVVERGQYDIFVERDGQSRCVGRYDNHGSFGELALMYNTPRAATIVATSEGALWGLDRVTFRRIILKNNAKKRKTYEIFIESVPVLKFLELSERMKIVDVIAARVYKDGDRIIAQGDKADCFFIVESGEVKIMMKSKTKTGQESNQEVEIARCKSGQYFGELALVTNKPRAASAYAVGDVKCLIMDVQAFERLLGPCMDIMKRNITHYEEQLVALFG 399
BLAST of cAMP-dependent protein kinase type II regulatory subunit vs. Ensembl Xenopus
Match: fgf1 (fibroblast growth factor 1 [Source:Xenbase;Acc:XB-GENE-485966]) HSP 1 Score: 190.66 bits (483), Expect = 1.099e-56 Identity = 103/275 (37.45%), Postives = 166/275 (60.36%), Query Frame = 1
Query: 406 IYPKTPKQMDKITDILETIFFFNCLDEIQFSKIIQSMFFIEVFKGDEIIKENDPGNNFYVIDYG---TFTASNKSKSIYEVYKGEGFFGELALLYNCPRSASVIADTDGGLWVIDRVTFRQLILKSAYQKRQRYLKFISSVPLLEDLTKYEQCNLADALKTKTI-NNEKVISQGDAGDKMYFIXXXXXXXXXXXXXXXXXXS-------RLKAGDYFGEVALLANIPRIANVYALGYTKLAELDAKSYTRLLGPCIDNMRKNFTKYRSQLEKLLS 1197
+ PKT +Q ++ + + I F LD+ Q S+++ +MF + V + +I + D G+NFYV++ G F + Y G FGELAL+YN PR+A+++A ++G LW +DRVTFR++ILK+ +KR+ Y FI SVP+L+ L E+ + D + + + +++I+QGD D + +E GEV + +++ + +ES R K+G YFGE+AL+ N PR A+ YA+G K +D +++ RLLGPC+D M++N T Y QL L
Sbjct: 19 VRPKTDEQRCRLQEACKDILLFKNLDQEQLSQVLDAMFEMRVKPQEHVIDQGDDGDNFYVVERGQYDIFVERDGQSRCVGRYDNHGSFGELALMYNTPRAATIVATSEGALWGLDRVTFRRIILKNNAKKRKTYEIFIESVPVLKFLELSERMKIVDVIAARVYKDGDRIIAQGDKADCFFIVESGEVKIMMKSKTKTGQESNQEVEIARCKSGQYFGELALVTNKPRAASAYAVGDVKCLIMDVQAFERLLGPCMDIMKRNITHYEEQLVALFG 293
BLAST of cAMP-dependent protein kinase type II regulatory subunit vs. Ensembl Mouse
Match: Prkar2a (protein kinase, cAMP dependent regulatory, type II alpha [Source:MGI Symbol;Acc:MGI:108025]) HSP 1 Score: 216.083 bits (549), Expect = 2.010e-65 Identity = 133/390 (34.10%), Postives = 214/390 (54.87%), Query Frame = 1
Query: 97 LTEVIEEFKKQVEIANPKDIIAYAATYFTKKVAQENESNDTEFDKSLDYDSSS--------EDGDSLKEIMSNDKSKMKLVQTSNVPRQSITCESFDPSSIDDETFEKN--RKIYPKTPKQMDKITDILETIFFFNCLDEIQFSKIIQSMFFIEVFKGDEIIKENDPGNNFYVIDYGTF----TASNKSKSIYEVYKGEGFFGELALLYNCPRSASVIADTDGGLWVIDRVTFRQLILKSAYQKRQRYLKFISSVPLLEDLTKYEQCNLADALKTKTI-NNEKVISQGDAGDKMYFIXX--------XXXXXXXXXXXXXXXXSRLKAGDYFGEVALLANIPRIANVYALGYTKLAELDAKSYTRLLGPCIDNMRKNFTKYRSQLEKLLS 1197
LTE+++ + +V P D++ +A YFT+ + +DT + + EDG+S + S D V + R S+ E+F+P DE E N R ++PKT +Q ++ + + I F LD+ Q S+++ +MF V + +I + D G+NFYVI+ GT+ T N+++S+ + Y G FGELAL+YN PR+A++IA ++G LW +DRVTFR++I+K+ +KR+ + FI SVPL + L E+ + D + K + E++I+QG+ D Y IE + G +E E + G YFGE+AL+ N PR A+ YA+G K +D +++ RLLGPC+D M++N + Y QL K+
Sbjct: 10 LTELLQGYTVEVLRQQPPDLVDFAVEYFTRLREARRQESDTFIVSPTTFHTQESSAVPVIEEDGESDSD--SEDADLEVPVPSKFTRRVSVCAETFNP----DEEEEDNDPRVVHPKTDEQRCRLQEACKDILLFKNLDQEQLSQVLDAMFEKIVKTDEHVIDQGDDGDNFYVIERGTYDILVTKDNQTRSVGQ-YDNRGSFGELALMYNTPRAATIIATSEGSLWGLDRVTFRRIIVKNNAKKRKMFESFIESVPLFKSLEMSERMKIVDVIGEKIYKDGERIIAQGEKADSFYIIESGEVSILIRSKTKSNKNGGNQEVEIAHCHKGQYFGELALVTNKPRAASAYAVGDVKCLVMDVQAFERLLGPCMDIMKRNISHYEEQLVKMFG 392
BLAST of cAMP-dependent protein kinase type II regulatory subunit vs. Ensembl Mouse
Match: Prkar2a (protein kinase, cAMP dependent regulatory, type II alpha [Source:MGI Symbol;Acc:MGI:108025]) HSP 1 Score: 206.453 bits (524), Expect = 5.285e-62 Identity = 127/386 (32.90%), Postives = 208/386 (53.89%), Query Frame = 1
Query: 97 LTEVIEEFKKQVEIANPKDIIAYAATYFTKKVAQENESNDTEFDKSLDYDSSS--------EDGDSLKEIMSNDKSKMKLVQTSNVPRQSITCESFDPSSIDDETFEKN--RKIYPKTPKQMDKITDILETIFFFNCLDEIQFSKIIQSMFFIEVFKGDEIIKENDPGNNFYVIDYGTF----TASNKSKSIYEVYKGEGFFGELALLYNCPRSASVIADTDGGLWVIDRVTFRQLILKSAYQKRQRYLKFISSVPLLEDLTKYEQCNLADALKTKTI-NNEKVISQG----DAGDKMYFIXXXXXXXXXXXXXXXXXXSRLKAGDYFGEVALLANIPRIANVYALGYTKLAELDAKSYTRLLGPCIDNMRKNFTKYRSQLEKLLS 1197
LTE+++ + +V P D++ +A YFT+ + +DT + + EDG+S + S D V + R S+ E+F+P DE E N R ++PKT +Q ++ + + I F LD+ Q S+++ +MF V + +I + D G+NFYVI+ GT+ T N+++S+ + Y G FGELAL+YN PR+A++IA ++G LW +DRVTFR++I+K+ +KR+ + FI SVPL + L E+ + D + K + E++I+Q + G++ I + G YFGE+AL+ N PR A+ YA+G K +D +++ RLLGPC+D M++N + Y QL K+
Sbjct: 10 LTELLQGYTVEVLRQQPPDLVDFAVEYFTRLREARRQESDTFIVSPTTFHTQESSAVPVIEEDGESDSD--SEDADLEVPVPSKFTRRVSVCAETFNP----DEEEEDNDPRVVHPKTDEQRCRLQEACKDILLFKNLDQEQLSQVLDAMFEKIVKTDEHVIDQGDDGDNFYVIERGTYDILVTKDNQTRSVGQ-YDNRGSFGELALMYNTPRAATIIATSEGSLWGLDRVTFRRIIVKNNAKKRKMFESFIESVPLFKSLEMSERMKIVDVIGEKIYKDGERIIAQTKSNKNGGNQEVEI------------------AHCHKGQYFGELALVTNKPRAASAYAVGDVKCLVMDVQAFERLLGPCMDIMKRNISHYEEQLVKMFG 370
BLAST of cAMP-dependent protein kinase type II regulatory subunit vs. Ensembl Mouse
Match: Prkar2b (protein kinase, cAMP dependent regulatory, type II beta [Source:MGI Symbol;Acc:MGI:97760]) HSP 1 Score: 206.453 bits (524), Expect = 1.396e-61 Identity = 128/401 (31.92%), Postives = 206/401 (51.37%), Query Frame = 1
Query: 97 LTEVIEEFKKQVEIANPKDIIAYAATYFTKKVAQENESNDT-----------EFDKSLDYDSSSEDGDSLKEIMSNDKSKMKL------------VQTSNVPRQSITCESFDPSSIDDETFEKNRKIYPKTPKQMDKITDILETIFFFNCLDEIQFSKIIQSMFFIEVFKGDEIIKENDPGNNFYVIDYGTFTASNKSKSIYEV---YKGEGFFGELALLYNCPRSASVIADTDGGLWVIDRVTFRQLILKSAYQKRQRYLKFISSVPLLEDLTKYEQCNLADALKTKTINN-EKVISQGDAGDKMYF-------IXXXXXXXXXXXXXXXXXXSRLKAGDYFGEVALLANIPRIANVYALGYTKLAELDAKSYTRLLGPCIDNMRKNFTKYRSQLEKLLS 1197
LTE+++ F +V P D++ +A +FT+ + QENE + + S+ + +E M +D + V R S+ E+++P +D+ ++R I+PKT Q +++ + + I F LD Q S+++ +MF V +G+ +I + D G+NFYVID GTF K + Y G FGELAL+YN PR+A++ A + G LW +DRVTFR++I+K+ +KR+ Y FI S+P L+ L E+ + D + TK N+ E++I+QGD D + I + E +R G YFGE+AL+ N PR A+ +A+G K +D +++ RLLGPC++ M++N Y QL L
Sbjct: 9 LTELLQGFTVEVLRHQPADLLEFALQHFTR-LQQENERKGAARFGHEGRTWGDAGAAAGGGIPSKGVNFAEEPMRSDSENGEEEEAAEAGAFNAPVINRFTRRASVCAEAYNPDEEEDDA--ESRIIHPKTDDQRNRLQEACKDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVIDRGTFDIYVKCDGVGRCVGNYDNRGSFGELALMYNTPRAATITATSPGALWGLDRVTFRRIIVKNNAKKRKMYESFIESLPFLKSLEVSERLKVVDVIGTKVYNDGEQIIAQGDLADSFFIVESGEVKITMKRKGKSEVEENGAVEIARCFRGQYFGELALVTNKPRAASAHAIGTVKCLAMDVQAFERLLGPCMEIMKRNIATYEEQLVALFG 406
BLAST of cAMP-dependent protein kinase type II regulatory subunit vs. Ensembl Mouse
Match: Prkar2b (protein kinase, cAMP dependent regulatory, type II beta [Source:MGI Symbol;Acc:MGI:97760]) HSP 1 Score: 206.453 bits (524), Expect = 1.396e-61 Identity = 128/401 (31.92%), Postives = 206/401 (51.37%), Query Frame = 1
Query: 97 LTEVIEEFKKQVEIANPKDIIAYAATYFTKKVAQENESNDT-----------EFDKSLDYDSSSEDGDSLKEIMSNDKSKMKL------------VQTSNVPRQSITCESFDPSSIDDETFEKNRKIYPKTPKQMDKITDILETIFFFNCLDEIQFSKIIQSMFFIEVFKGDEIIKENDPGNNFYVIDYGTFTASNKSKSIYEV---YKGEGFFGELALLYNCPRSASVIADTDGGLWVIDRVTFRQLILKSAYQKRQRYLKFISSVPLLEDLTKYEQCNLADALKTKTINN-EKVISQGDAGDKMYF-------IXXXXXXXXXXXXXXXXXXSRLKAGDYFGEVALLANIPRIANVYALGYTKLAELDAKSYTRLLGPCIDNMRKNFTKYRSQLEKLLS 1197
LTE+++ F +V P D++ +A +FT+ + QENE + + S+ + +E M +D + V R S+ E+++P +D+ ++R I+PKT Q +++ + + I F LD Q S+++ +MF V +G+ +I + D G+NFYVID GTF K + Y G FGELAL+YN PR+A++ A + G LW +DRVTFR++I+K+ +KR+ Y FI S+P L+ L E+ + D + TK N+ E++I+QGD D + I + E +R G YFGE+AL+ N PR A+ +A+G K +D +++ RLLGPC++ M++N Y QL L
Sbjct: 9 LTELLQGFTVEVLRHQPADLLEFALQHFTR-LQQENERKGAARFGHEGRTWGDAGAAAGGGIPSKGVNFAEEPMRSDSENGEEEEAAEAGAFNAPVINRFTRRASVCAEAYNPDEEEDDA--ESRIIHPKTDDQRNRLQEACKDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVIDRGTFDIYVKCDGVGRCVGNYDNRGSFGELALMYNTPRAATITATSPGALWGLDRVTFRRIIVKNNAKKRKMYESFIESLPFLKSLEVSERLKVVDVIGTKVYNDGEQIIAQGDLADSFFIVESGEVKITMKRKGKSEVEENGAVEIARCFRGQYFGELALVTNKPRAASAHAIGTVKCLAMDVQAFERLLGPCMEIMKRNIATYEEQLVALFG 406
BLAST of cAMP-dependent protein kinase type II regulatory subunit vs. Ensembl Mouse
Match: Prkar1b (protein kinase, cAMP dependent regulatory, type I beta [Source:MGI Symbol;Acc:MGI:97759]) HSP 1 Score: 180.259 bits (456), Expect = 4.659e-52 Identity = 123/376 (32.71%), Postives = 194/376 (51.60%), Query Frame = 1
Query: 58 NCNMNNQNYSKKILTEVIEEFKKQVEIANPKDIIAYAATYFTKKVAQENESNDTEFDKSLDYDSSSEDGDSLKEIMSNDKSKMKLVQTSNVPRQSITCESFDPSSIDDETFEKNRKIYPKTPKQMDKITDILETIFFFNCLDEIQFSKIIQSMFFIEVFKGDEIIKENDPGNNFYVIDYGTFTASNKSKSIYEVYKGEGFFGELALLYNCPRSASVIADTDGGLWVIDRVTFRQLILKSAYQKRQRYLKFISSVPLLEDLTKYEQCNLADALKTKTI-NNEKVISQGDAGDKMYFIXXXXXXXXXXXXXXX--XXXSRLKAGDYFGEVALLANIPRIANVYALGYTKLAELDAKSYTRLLGPCIDNMRKNFTKYRS 1176
C M Q + + +V++E + +A P + + +F K +EN + L S+ DS E +S + V + R ++ E + +++ RK+ PK K M + + F+ LD+ + S I +MF + G+ +I++ + G+NFYVID G + + + +G G FGELAL+Y PR+A+V A TD LW IDR ++R++++ S +KR+ Y +F+S V +LE L K+E+ +ADAL+ + EK++ QG+ GD Y I EG V R E E RL DYFGE+ALL N PR A V A G K +LD + R+LGPC + +++N +Y S
Sbjct: 17 GCEMYVQKHG---IQQVLKECIVHLCVAKPDRPLRFLREHFEKLEKEENR-------QILARQKSNSQCDSHDEEIS--PTPPNPVVKARRRRGGVSAEVY----TEEDAVSYVRKVIPKDYKTMTALAKAISKNVLFSHLDDNERSDIFDAMFPVTHIGGETVIQQGNEGDNFYVIDQGEVDVYVNGEWVTNISEG-GSFGELALIYGTPRAATVKAKTDLKLWGIDRDSYRRILMGSTLRKRKMYEEFLSKVSILESLEKWERLTVADALEPVQFEDGEKIVVQGEPGDDFYIITEGTASVLQRRSPNEEYVEVGRLGPSDYFGEIALLLNRPRAATVVARGPLKCVKLDRPRFERVLGPCSEILKRNIQRYNS 375
BLAST of cAMP-dependent protein kinase type II regulatory subunit vs. UniProt/SwissProt
Match: sp|P81900|KAPR2_DROME (cAMP-dependent protein kinase type II regulatory subunit OS=Drosophila melanogaster OX=7227 GN=Pka-R2 PE=1 SV=2) HSP 1 Score: 258.07 bits (658), Expect = 3.856e-81 Identity = 148/369 (40.11%), Postives = 226/369 (61.25%), Query Frame = 1
Query: 97 LTEVIEEFKKQVEIANPKDIIAYAATYFTKKVAQENESNDTEFDKSLDYDSSSEDGDSLKEIMSNDKSKMKLVQTSNVPRQSITCESFDPSSIDDETFEKNRKIYPKTPKQMDKITDILETIFFFNCLDEIQFSKIIQSMFFIEVFKGDEIIKENDPGNNFYVIDYGTFTASNKSKSIYEVYKGEGFFGELALLYNCPRSASVIADTDGGLWVIDRVTFRQLILKSAYQKRQRYLKFISSVPLLEDLTKYEQCNLADALKTKTINN-EKVISQGDAGDKMYFIXXXXXXXXXXXXXXXXXXSRLKAGDYFGEVALLANIPRIANVYAL-GYTKLAELDAKSYTRLLGPCIDNMRKNFTKYRSQLEKLLS 1197
L EV+ +F + P D+I YA YFTK ++ + T+ +S+D D+ +M++ + R+S+ E++DP + + + ++PKT +Q ++ + ++ + F L++ Q ++++ +MF +V GD II++ D G+NFYVI+ G + K I Y G FGELALLYN PR+A+V A+T G LW +DR TFR+++LKSA++KR+ Y + ++SVP+L+ L YE+ NLADAL +K+ +N E++I QGDA D MYFIEEG V V + + E E S+L G YFGE+AL+ + PR A+VYA G KLA LD K++ RLLGPC+D M++N Y SQL K+
Sbjct: 15 LKEVLLQFSISFLVEQPPDVIDYAVEYFTKLQSERPSVSHTDQSTDDQLSVNSQDADAEPPVMASSR------------RKSVFAEAYDPEAD--DDDDGATAVFPKTDEQRARLVESVKNVLLFRSLEKEQMNQVLDAMFERKVQPGDFIIRQGDDGDNFYVIESGVYKVYINDKHI-NTYNHTGLFGELALLYNMPRAATVQAETSGLLWAMDRQTFRRILLKSAFRKRKMYEELLNSVPMLKALQNYERMNLADALVSKSYDNGERIIKQGDAADGMYFIEEGTVSVRMDQDDAEVEISQLGKGQYFGELALVTHRPRAASVYATGGVVKLAFLDVKAFERLLGPCMDIMKRNIDDYESQLVKIFG 368
BLAST of cAMP-dependent protein kinase type II regulatory subunit vs. UniProt/SwissProt
Match: sp|Q26619|KAPR_STRPU (cAMP-dependent protein kinase type II regulatory subunit OS=Strongylocentrotus purpuratus OX=7668 PE=2 SV=1) HSP 1 Score: 221.09 bits (562), Expect = 6.834e-67 Identity = 137/377 (36.34%), Postives = 216/377 (57.29%), Query Frame = 1
Query: 97 LTEVIEEFKKQVEIANPKDIIAYAATYFTKKVAQENESNDTEFDKSLDYDSSSEDGDSLKEIMSNDKSKMKLVQTSNVPRQSITCESFDPSSIDDETFEKNRKIYPKTPKQMDKITDILETIFFFNCLDEIQFSKIIQSMFFIEVFKGDEIIKENDPGNNFYVID---YGTFTASNKSKSIYEVYKGEGFFGELALLYNCPRSASVIADTDGGLWVIDRVTFRQLILKSAYQKRQRYLKFISSVPLLEDLTKYEQCNLADALKTKTI-NNEKVISQGDAGDKMYFIXXXXXXXXXXXXXXXXXXSRLKA-----GDYFGEVALLANIPRIANVYALGYTKLAELDAKSYTRLLGPCIDNMRKNFTKYRSQLEKLLSR 1200
LT+++++F V P D++ +A++YF K QEN N + K ++ ED +S D +L + R+S+ E +DP + +D +K +YPK+ +Q ++T+ ++ I F LDE Q ++I +MF + GD +I + D G+NFYVID Y F NK + YK G FGELAL+YN PR+A++ A TDG LW +DRV+FR+++LK+A +KR+ Y + + V + + L YE+ NLADAL T+T + + +I+QGD D YFIE G+ + +++ + + + G YFGE+ALL N PR A+VYA+ LD ++ RLLGPC+D M++N Y + +L +
Sbjct: 9 LTDLLQDFTVAVLREKPSDLVEFASSYFAK--LQEN--NISLGGKRGVTFTAPEDAES-----DIDDEPPELPKNRYARRKSVCAEKYDPEADNDTDTQK--LVYPKSDEQRARLTEAVKNILLFRALDEKQMQEVIDAMFEKKTTPGDHVIDQGDDGDNFYVIDRGEYDIFVNDNKVGA----YKDSGSFGELALMYNTPRAATIAATTDGILWALDRVSFRRIVLKNAAKKRRIYEELLEKVSIFKSLEPYERMNLADALVTRTYEDGDCIIAQGDGADGCYFIEAGQCRIAMKSERSDNPDEEKEVAIYNQGQYFGELALLTNKPRAASVYAVEDVDCL-LDVNAFERLLGPCMDIMKRNIEHYEQETSRLFGK 369
BLAST of cAMP-dependent protein kinase type II regulatory subunit vs. UniProt/SwissProt
Match: sp|P00515|KAP2_BOVIN (cAMP-dependent protein kinase type II-alpha regulatory subunit OS=Bos taurus OX=9913 GN=PRKAR2A PE=1 SV=2) HSP 1 Score: 215.698 bits (548), Expect = 1.786e-64 Identity = 132/385 (34.29%), Postives = 221/385 (57.40%), Query Frame = 1
Query: 97 LTEVIEEFKKQVEIANPKDIIAYAATYFTK-KVAQENESNDTEFDKSLDYDSSSEDG---DSLKEIMSNDKSKMKLVQTSNVPRQ-SITCESFDPSSIDDETFEKNRKIYPKTPKQMDKITDILETIFFFNCLDEIQFSKIIQSMFFIEVFKGDEIIKENDPGNNFYVIDYGTF----TASNKSKSIYEVYKGEGFFGELALLYNCPRSASVIADTDGGLWVIDRVTFRQLILKSAYQKRQRYLKFISSVPLLEDLTKYEQCNLADALKTKTI-NNEKVISQGDAGDKMYFIXXXXXXXXXXXXX--------XXXXXSRLKAGDYFGEVALLANIPRIANVYALGYTKLAELDAKSYTRLLGPCIDNMRKNFTKYRSQLEKLLS 1197
LTE+++ + +V P D++ +A YFT+ + A+ S S D G D++ + S D+ + + R+ S+ E+++P +++T R I+PKT +Q ++ + + I F LD Q S+++ +MF V + +I + D G+NFYVI+ GT+ T N+++S+ + Y G FGELAL+YN PR+A+++A ++G LW +DRVTFR++I+K+ +KR+ + FI SVPLL+ L E+ + D + K + E++I+QG+ D Y IE GEV + +++ +E E +R G YFGE+AL+ N PR A+ YA+G K +D +++ RLLGPC+D M++N + Y QL K+
Sbjct: 10 LTELLQGYTVEVLRQRPPDLVDFAVDYFTRLREARSRASTPPAAPPSGSQDFDPGAGLVADAVADSESEDEEDLDVPIPGRFDRRVSVCAETYNPDEEEEDT--DPRVIHPKTDQQRCRLQEACKDILLFKNLDPEQLSQVLDAMFERTVKVDEHVIDQGDDGDNFYVIERGTYDILVTKDNQTRSVGQ-YDNHGSFGELALMYNTPRAATIVATSEGSLWGLDRVTFRRIIVKNNAKKRKMFESFIESVPLLKSLEVSERMKIVDVIGEKVYKDGERIITQGEKADSFYIIESGEVSILIKSKTKVNKDGENQEVEIARCHKGQYFGELALVTNKPRAASAYAVGDVKCLVMDVQAFERLLGPCMDIMKRNISHYEEQLVKMFG 391
BLAST of cAMP-dependent protein kinase type II regulatory subunit vs. UniProt/SwissProt
Match: sp|P31323|KAP3_HUMAN (cAMP-dependent protein kinase type II-beta regulatory subunit OS=Homo sapiens OX=9606 GN=PRKAR2B PE=1 SV=3) HSP 1 Score: 214.157 bits (544), Expect = 1.256e-63 Identity = 130/403 (32.26%), Postives = 211/403 (52.36%), Query Frame = 1
Query: 97 LTEVIEEFKKQVEIANPKDIIAYAATYFTKKVAQENESNDT-----------EFDKSLDYDSSSEDGDSLKEIMSNDKSKMKLVQTS-------NVP-------RQSITCESFDPSSIDDETFEKNRKIYPKTPKQMDKITDILETIFFFNCLDEIQFSKIIQSMFFIEVFKGDEIIKENDPGNNFYVIDYGTFTASNKSKSIYEV---YKGEGFFGELALLYNCPRSASVIADTDGGLWVIDRVTFRQLILKSAYQKRQRYLKFISSVPLLEDLTKYEQCNLADALKTKTINN-EKVISQGDAGDKMYF-------IXXXXXXXXXXXXXXXXXXSRLKAGDYFGEVALLANIPRIANVYALGYTKLAELDAKSYTRLLGPCIDNMRKNFTKYRSQLEKLLS 1197
LTE+++ F +V P D++ +A +FT+ + QENE T + + + S+ + +E M +D + + + N P R S+ E+++P +D+ ++R I+PKT Q +++ + + I F LD Q S+++ +MF V G+ +I + D G+NFYVID GTF K + Y G FGELAL+YN PR+A++ A + G LW +DRVTFR++I+K+ +KR+ Y FI S+P L+ L E+ + D + TK N+ E++I+QGD+ D + I + E +R G YFGE+AL+ N PR A+ +A+G K +D +++ RLLGPC++ M++N Y QL L
Sbjct: 9 LTELLQGFTVEVLRHQPADLLEFALQHFTR-LQQENERKGTARFGHEGRTWGDLGAAAGGGTPSKGVNFAEEPMQSDSEDGEEEEAAPADAGAFNAPVINRFTRRASVCAEAYNPDEEEDDA--ESRIIHPKTDDQRNRLQEACKDILLFKNLDPEQMSQVLDAMFEKLVKDGEHVIDQGDDGDNFYVIDRGTFDIYVKCDGVGRCVGNYDNRGSFGELALMYNTPRAATITATSPGALWGLDRVTFRRIIVKNNAKKRKMYESFIESLPFLKSLEFSERLKVVDVIGTKVYNDGEQIIAQGDSADSFFIVESGEVKITMKRKGKSEVEENGAVEIARCSRGQYFGELALVTNKPRAASAHAIGTVKCLAMDVQAFERLLGPCMEIMKRNIATYEEQLVALFG 408
BLAST of cAMP-dependent protein kinase type II regulatory subunit vs. UniProt/SwissProt
Match: sp|P13861|KAP2_HUMAN (cAMP-dependent protein kinase type II-alpha regulatory subunit OS=Homo sapiens OX=9606 GN=PRKAR2A PE=1 SV=2) HSP 1 Score: 213.386 bits (542), Expect = 1.534e-63 Identity = 134/389 (34.45%), Postives = 223/389 (57.33%), Query Frame = 1
Query: 97 LTEVIEEFKKQVEIANPKDIIAYAATYFTK-KVAQENES--NDTEFDKSLDYDSSSEDGDSLKEIMSNDKSKMKLVQTSNVP-----RQSITCESFDPSSIDDETFEKNRKIYPKTPKQMDKITDILETIFFFNCLDEIQFSKIIQSMFFIEVFKGDE-IIKENDPGNNFYVIDYGTF----TASNKSKSIYEVYKGEGFFGELALLYNCPRSASVIADTDGGLWVIDRVTFRQLILKSAYQKRQRYLKFISSVPLLEDLTKYEQCNLADALKTKTI-NNEKVISQGDAGDKMYFIXXXXXXXXXXXXXXX--------XXXSRLKAGDYFGEVALLANIPRIANVYALGYTKLAELDAKSYTRLLGPCIDNMRKNFTKYRSQLEKLLS 1197
LTE+++ + +V P D++ +A YFT+ + A+ S +SL + D + + + +S+ VP R S+ E+++P +++T R I+PKT +Q ++ + + I F LD+ Q S+++ +MF + K DE +I + D G+NFYVI+ GT+ T N+++S+ + Y G FGELAL+YN PR+A+++A ++G LW +DRVTFR++I+K+ +KR+ + FI SVPLL+ L E+ + D + K + E++I+QG+ D Y IE GEV + +R+ + E +R G YFGE+AL+ N PR A+ YA+G K +D +++ RLLGPC+D M++N + Y QL K+
Sbjct: 10 LTELLQGYTVEVLRQQPPDLVEFAVEYFTRLREARAPASVLPAATPRQSLGHPPPEPGPDRVADAKGDSESEEDEDLEVPVPSRFNRRVSVCAETYNPDEEEEDT--DPRVIHPKTDEQRCRLQEACKDILLFKNLDQEQLSQVLDAMFE-RIVKADEHVIDQGDDGDNFYVIERGTYDILVTKDNQTRSVGQ-YDNRGSFGELALMYNTPRAATIVATSEGSLWGLDRVTFRRIIVKNNAKKRKMFESFIESVPLLKSLEVSERMKIVDVIGEKIYKDGERIITQGEKADSFYIIESGEVSILIRSRTKSNKDGGNQEVEIARCHKGQYFGELALVTNKPRAASAYAVGDVKCLVMDVQAFERLLGPCMDIMKRNISHYEEQLVKMFG 394
BLAST of cAMP-dependent protein kinase type II regulatory subunit vs. TrEMBL
Match: A0A3Q0KLT7 (Putative camp-dependent protein kinase type II regulatory subunit OS=Schistosoma mansoni OX=6183 PE=4 SV=1) HSP 1 Score: 262.692 bits (670), Expect = 1.204e-80 Identity = 137/297 (46.13%), Postives = 201/297 (67.68%), Query Frame = 1
Query: 334 RQSITCESFDPSSIDDETFEKNRKIYPKTPKQMDKITDILETIFFFNCLDEIQFSKIIQSMFFIEVFKGDEIIKENDPGNNFYVIDYGTF------TASNKSKSIYEV--YKGEGFFGELALLYNCPRSASVIADTDGGLWVIDRVTFRQLILKSAYQKRQRYLKFISSVPLLEDLTKYEQCNLADALKTKTI-NNEKVISQGDAGDKMYFIXXXXXXXXXXXXXXXXXXSRLKAGDYFGEVALLANIPRIANVYALGYTKLAELDAKSYTRLLGPCIDNMRKNFTKYRSQLEKLLS 1197
RQS+ ESFDP D+ E+ R+IYPK+ Q ++T+ ++ I F CLDE Q SK+I +M ++V +GD +IK+ D G+NFYVI+ GT+ SN K +V Y G+G FGELAL+YN R+AS+IA T+G LW++DR TFR+++LK+A+ KRQ Y++ + +PLL++L+ YE+ N+ADAL+++ + +ISQG+ G +M+ IE G V ++V+ +E E SRL G YFGE+AL+ PR A+ YA+G TKLA LD S+ RL+GPC+ M++N Y QL +LL
Sbjct: 54 RQSVAAESFDPEKDSDDNNEEERRIYPKSDSQRSRLTNAVKEILLFRCLDEEQKSKVIDAMQEMKVKEGDVVIKQGDDGDNFYVIESGTYDIYVKQNQSNDEKLGEKVGSYNGQGSFGELALMYNTSRAASIIATTNGILWLMDRNTFRRIVLKAAFHKRQTYVELLEDIPLLKELSSYERTNVADALQSRIYQDGATIISQGETGKEMFIIESGTVRISVKENSKEVELSRLGKGAYFGELALITKRPRAASAYAVGETKLAVLDVASFERLMGPCLKVMQRNIDTYEKQLSELLG 350
BLAST of cAMP-dependent protein kinase type II regulatory subunit vs. TrEMBL
Match: A0A095C9J6 (cAMP-dependent protein kinase type II regulatory subunit (Fragment) OS=Schistosoma haematobium OX=6185 GN=MS3_07384 PE=4 SV=1) HSP 1 Score: 261.151 bits (666), Expect = 2.208e-80 Identity = 134/303 (44.22%), Postives = 200/303 (66.01%), Query Frame = 1
Query: 316 QTSNVPRQSITCESFDPSSIDDETFEKNRKIYPKTPKQMDKITDILETIFFFNCLDEIQFSKIIQSMFFIEVFKGDEIIKENDPGNNFYVIDYGTFTASNKSKSIYE--------VYKGEGFFGELALLYNCPRSASVIADTDGGLWVIDRVTFRQLILKSAYQKRQRYLKFISSVPLLEDLTKYEQCNLADALKTKTI-NNEKVISQGDAGDKMYFIXXXXXXXXXXXXXXXXXXSRLKAGDYFGEVALLANIPRIANVYALGYTKLAELDAKSYTRLLGPCIDNMRKNFTKYRSQLEKLLS 1197
+ S + RQS+ ESFDP D+ E+ R+IYPK+ Q ++T+ ++ I F CLDE Q S++I +M ++V +GD +IK+ D G+NFYVI+ GT+ K E Y G G FGELAL+YN R+AS+IA TDG LW++DR TFR+++LK+A+ KRQ Y++ + +PLL++L+ YE+ N+ADAL+++ + +ISQG+ G +M+ I+ G V ++V+ +E E SR+ G YFGE+AL+ PR A+ YA+G TKLA LD S+ RL+GPC+ M++N Y QL +LL
Sbjct: 34 RNSLLRRQSVAAESFDPEKDSDDNNEEERQIYPKSDSQRARLTNAVKEILLFRCLDEEQKSRVIDAMQEMKVKEGDVVIKQGDDGDNFYVIESGTYDIYVKQNQSTEEKIGEKVGSYNGHGSFGELALMYNTSRAASIIATTDGILWLMDRNTFRRIVLKAAFHKRQTYVELLEDIPLLKELSSYERTNVADALQSRVYQDGSTIISQGETGKEMFIIQSGTVRISVKENSKEVELSRVGKGAYFGELALITKRPRAASAYAVGETKLAVLDVASFERLMGPCLKVMQRNIDTYEKQLTELLG 336
BLAST of cAMP-dependent protein kinase type II regulatory subunit vs. TrEMBL
Match: A0A3B0IZR1 (Blast:cAMP-dependent protein kinase type II regulatory subunit OS=Drosophila guanche OX=7266 GN=DGUA_6G001143 PE=4 SV=1) HSP 1 Score: 259.61 bits (662), Expect = 3.510e-79 Identity = 150/369 (40.65%), Postives = 226/369 (61.25%), Query Frame = 1
Query: 97 LTEVIEEFKKQVEIANPKDIIAYAATYFTKKVAQENESNDTEFDKSLDYDSSSEDGDSLKEIMSNDKSKMKLVQTSNVPRQSITCESFDPSSIDDETFEKNRKIYPKTPKQMDKITDILETIFFFNCLDEIQFSKIIQSMFFIEVFKGDEIIKENDPGNNFYVIDYGTFTASNKSKSIYEVYKGEGFFGELALLYNCPRSASVIADTDGGLWVIDRVTFRQLILKSAYQKRQRYLKFISSVPLLEDLTKYEQCNLADALKTKTI-NNEKVISQGDAGDKMYFIXXXXXXXXXXXXXXXXXXSRLKAGDYFGEVALLANIPRIANVYAL-GYTKLAELDAKSYTRLLGPCIDNMRKNFTKYRSQLEKLLS 1197
L EV+ +F + P D+I YAA YF K A + + + +S+DG+ +M N + R+S+ E++DP + DD+ E I+PKT +Q ++ + ++ + F L++ Q ++++ +MF +V GD II++ D G+NFYVI+ G + K I Y G FGELALLYN PR+A+V A+T+G LW +DR TFR+++LKSA++KR+ Y + +++VP+L+ L YE+ NLADAL TK+ E++I QGDA D MYFIEEG V V + + E E S+L G YFGE+AL+ + PR A+VYA G+ +LA LD +++ RLLGPC+D M++N Y SQL K+
Sbjct: 15 LKEVLLQFSIAYLVEQPPDVIDYAADYFNKLQANRPAPANQDQSQDDQQSINSQDGEE-PPVMQNSR------------RKSVFAEAYDPEADDDD--EGATAIFPKTDEQRSRLVESVKNVLLFRSLEKEQMNQVLDAMFERKVQPGDYIIRQGDDGDNFYVIESGIYKVYINDKHI-NTYNHTGLFGELALLYNMPRAATVQAETNGLLWAMDRQTFRRILLKSAFKKRKMYEELLNNVPMLKALQNYERMNLADALITKSFEGGERIIKQGDAADGMYFIEEGTVSVRMDQDDAEVEISQLGKGQYFGELALVTHRPRAASVYATGGHVRLAFLDVRAFERLLGPCMDIMKRNIDDYESQLVKIFG 367
BLAST of cAMP-dependent protein kinase type II regulatory subunit vs. TrEMBL
Match: T1E240 (Putative camp-dependent protein kinase r2 OS=Psorophora albipes OX=869069 PE=2 SV=1) HSP 1 Score: 259.61 bits (662), Expect = 3.806e-79 Identity = 152/370 (41.08%), Postives = 228/370 (61.62%), Query Frame = 1
Query: 97 LTEVIEEFKKQVEIANPKDIIAYAATYFTKKVAQENESNDTEFDKSLDYDSSSEDGDSLKEIMSNDKSKMKLVQTSNVPRQSITCESFDPSSIDDETFEKNRKIYPKTPKQMDKITDILETIFFFNCLDEIQFSKIIQSMFFIEVFKGDEIIKENDPGNNFYVIDYGTFTA--SNKSKSIYEVYKGEGFFGELALLYNCPRSASVIADTDGGLWVIDRVTFRQLILKSAYQKRQRYLKFISSVPLLEDLTKYEQCNLADALKTKTIN-NEKVISQGDAGDKMYFIXXXXXXXXXXXXXXXXXXSRLKAGDYFGEVALLANIPRIANVYALGYTKLAELDAKSYTRLLGPCIDNMRKNFTKYRSQLEKLLS 1197
L +V+ EF + P D+I YA +F+K QEN N +++E + IMS+++ LV R+S+ E++DP + + + R I+PKT +Q ++ D ++ I F LD+ Q ++++ +MF +V GD IIK+ D G+NFYVI+ G + A K I+ Y G G FGELALLYN PR+A++ A+TDG LW +DR TFR+++LKSA++KR+ Y + +VP+L+ L YE+ NLADAL KT + +++I QGDA D MYFIE+G V + ++ E E SRL+ G YFGE+AL+ + PR A+ YA+G K+A LD ++ RLLGPC++ M++N Y SQL K+
Sbjct: 15 LRDVLLEFSIAYLLEQPGDVIDYAVEFFSK--LQENRKNTM--------ITAAEPTSPDESIMSHEEEP--LVNRYASRRKSVFAETYDPEAD--DDDDGARAIFPKTDEQRARLCDSVKNILLFRSLDKEQMNEVLDAMFEKKVKAGDYIIKQGDDGDNFYVIESGVYKAYVGEDLKHIH-TYNGSGSFGELALLYNMPRAATIQAETDGQLWAMDRQTFRRILLKSAFRKRKMYEALLDAVPMLKTLQNYERMNLADALIPKTYSVGDRIIKQGDAADGMYFIEDGTVSIRIQQDAGEVEISRLEKGQYFGELALVTHRPRAASAYAVGTVKVAFLDVDAFERLLGPCMEIMKRNIDDYESQLVKIFG 369
BLAST of cAMP-dependent protein kinase type II regulatory subunit vs. TrEMBL
Match: A0A4Z2CNG3 (cAMP-dependent protein kinase type II regulatory subunit isoform 2 OS=Schistosoma japonicum OX=6182 GN=EWB00_008963 PE=4 SV=1) HSP 1 Score: 258.07 bits (658), Expect = 7.360e-79 Identity = 133/301 (44.19%), Postives = 201/301 (66.78%), Query Frame = 1
Query: 334 RQSITCESFDPSSIDDETFEKNRKIYPKTPKQMDKITDILETIFFFNCLDEIQFSKIIQSMFFIEVFKGDEIIKENDPGNNFYVIDYGTF--------TASNKSKSIYEVYKGEGFFGELALLYNCPRSASVIADTDGGLWVIDRVTFRQLILKSAYQKRQRYLKFISSVPLLEDLTKYEQCNLADALKTKTI-NNEKVISQGDAGDKMYFIXXXXXXXXXXXXXXXXXXSRLKAGDYFGEVALLANIPRIANVYALGYTKLAELDAKSYTRLLGPCIDNMRKNFTKYRSQLEKLLS--RH 1203
RQS+ ESFDP D+ E+ R+IYPK+ Q ++T+ ++ I F CLDE Q SK+I +M ++V +GD +I + D G+NFYVI+ GT+ +++ K Y G+G FGELAL+YN R+AS++A TDG LW++DR TFR+++LK+A+ KRQ Y++ + +PLL++L+ YE+ N+ADAL+++ + +I+QG+ G +M+ IE G V ++V+ EE E SR+ G YFGE+AL+ PR A+ YA+G TK+A LD S+ RL+GPC+ M++N Y QL +LL RH
Sbjct: 54 RQSVAAESFDPEKDSDDNNEEERQIYPKSDSQRARLTNAVKEILLFRCLDEEQKSKVIDAMQEMKVKQGDVVITQGDDGDNFYVIESGTYDIYVRQNQSSNEKLGEKVGSYNGQGSFGELALMYNTSRAASIVAATDGILWLMDRNTFRRIVLKAAFHKRQAYIELLEDIPLLKELSSYERTNVADALQSRVYQDGATIITQGETGKEMFIIESGTVRISVKENSEEVELSRVGKGAYFGELALITKRPRAASAYAVGQTKVAVLDVASFERLMGPCLKVMQRNIDTYEKQLNELLGTDRH 354
BLAST of cAMP-dependent protein kinase type II regulatory subunit vs. Ensembl Cavefish
Match: si:ch211-272n13.7 (protein kinase cAMP-dependent type II regulatory subunit beta [Source:NCBI gene;Acc:103029925]) HSP 1 Score: 215.312 bits (547), Expect = 3.002e-65 Identity = 138/398 (34.67%), Postives = 218/398 (54.77%), Query Frame = 1
Query: 97 LTEVIEEFKKQVEIANPKDIIAYAATYFTKKVAQENESNDTEFDKSLDYDSSSEDGDS---LKEIMSNDKSK----------MKLVQTSNVPRQSITCESFDPSSIDDETFEKNRKIYPKTPKQMDKITDILETIFFFNCLDEIQFSKIIQSMFFIEVFKGDEIIKENDPGNNFYVIDYGTF---TASNKSKSIYEVYKGEGFFGELALLYNCPRSASVIADTDGGLWVIDRVTFRQLILKSAYQKRQRYLKFISSVPLLEDLTKYEQCNLADALKTKTIN-NEKVISQGDAGDKMYF-------IXXXXXXXXXXXXXXXXXXSRLKAGDYFGEVALLANIPRIANVYALGYTKLAELDAKSYTRLLGPCIDNMRKNFTKYRSQLEKLL-SRHQLEE 1215
LTE+++ F +V P+D++ +A YFT+ +ENES F + +S+ G + ++E M D + V + R S+ E+F+P DDE E R +PKT +Q ++ + + I F LD+ Q S+++ +MF V G+ II ++D G+NFYVI+ GTF S+ + Y G FGELAL+YN PR+A+++A + G LW +DR+TFR++I+K+ +KR+ Y FI ++PLL L E+ + D L +K + E++I+QGD D Y I + + EEE + + G YFGE+AL+ N PR A+ YA+ K +D +++ RLLGPC+D M++N Y QL L S+ ++EE
Sbjct: 9 LTELLQSFTVEVLRNQPRDLLEFALQYFTQ--LKENESRGGAFGN--EQNSAVRAGKAVNFIEEAMQIDSENEEDEDDDEEFVAPVINRFIRRASVCAEAFNPDE-DDEDKEP-RVTHPKTDEQRHRLQEACKDILLFKNLDQEQMSQVLDAMFDKAVTSGEHIIDQDDDGDNFYVIERGTFDILVKSDGTSRTVGSYDNRGSFGELALMYNTPRAATIVATSPGALWCLDRLTFRRIIVKNNAKKRKMYEAFIETLPLLTSLEVSERMKVVDVLSSKVYSKGEQIIAQGDLADSFYIVESGEVRITMKRNRLKTDSEEEEVDIATCTRGQYFGELALVTNKPRAASAYAVENVKCLVMDVQAFERLLGPCMDIMKRNIANYEEQLVTLFGSQTEIEE 400
BLAST of cAMP-dependent protein kinase type II regulatory subunit vs. Ensembl Cavefish
Match: prkar2aa (protein kinase, cAMP-dependent, regulatory, type II, alpha A [Source:ZFIN;Acc:ZDB-GENE-030131-1007]) HSP 1 Score: 195.667 bits (496), Expect = 4.320e-58 Identity = 125/388 (32.22%), Postives = 195/388 (50.26%), Query Frame = 1
Query: 97 LTEVIEEFKKQVEIANPKDIIAYAATYFTKKVAQENESNDTEFDKSLDYDSSSEDGDSLKEIMSNDKSKMKLVQTSNVPRQS----------------ITCESFDPSSIDDETFEKNRKIYPKTPKQMDKITDILETIFFFNCLDEIQFSKIIQSMFFIEVFKGDEIIKENDPGNNFYVIDYGTF---TASNKSKSIYEVYKGEGFFGELALLYNCPRSASVIADTDGGLWVIDRVTFRQLILKSAYQKRQRYLKFISSVPLLEDLTKYEQCNLADALKTKTINN-EKVISQGDAGDKMYF-------IXXXXXXXXXXXXXXXXXXSRLKAGDYFGEVALLANIPRIANVYALGYTKLAELDAKSYTRLLGPCIDNMRKNFTKYRSQ 1179
LTE+++ + +V P D++ +A YFT+ D+ S+DG S +K K V P Q+ + E +P D+++ + R ++PKT +Q ++ + + I F LD+ QFS+++ +MF + V + +I + D G+NFYVI+ G + + Y +G FGELAL+YN PR+A++IA +G LW +DR TFR+LI+K+ +KR+ Y FI SVPLL+ L E+ + D L K ++ E++I QGD D Y I R E E +R G YFGE+AL+ N PR + YA+G K +D +++ RLLGPC + M++N Y Q
Sbjct: 9 LTELLQGYTVEVLRQRPPDLVEFAVQYFTRL-----------------RDTRSQDG-------SGAAAKGKGVMFDGEPMQTESNGDEDDEDDDSDFELCAEPLNPDDDDEDS--EPRVVHPKTDEQRCRLQEACKDILLFKALDQEQFSEVLDAMFEVIVQPQEHVIDQGDDGDNFYVIERGVYDIVVQKDGVGCCVGQYDNKGSFGELALMYNTPRAATIIAKQEGALWGLDRATFRRLIVKNNAKKRRMYECFIESVPLLKSLEISERMKIVDVLGVKIFHDGERIIMQGDMADCFYIVESGEVKIMMKSKTKADRQDNAEVEITRCTRGQYFGELALVTNKPRAGSAYAVGDIKCLVIDVQAFERLLGPCKEIMKRNIAHYEEQ 370
BLAST of cAMP-dependent protein kinase type II regulatory subunit vs. Ensembl Cavefish
Match: prkar2ab (protein kinase, cAMP-dependent, regulatory, type II, alpha, B [Source:ZFIN;Acc:ZDB-GENE-040426-2427]) HSP 1 Score: 189.119 bits (479), Expect = 1.206e-55 Identity = 124/371 (33.42%), Postives = 200/371 (53.91%), Query Frame = 1
Query: 97 LTEVIEEFKKQVEIANPKDIIAYAATYFTKKVAQENESNDTEFDKSLDYDSSSEDGDSLKEIMSNDKSKMKLVQTSNVPRQSITCESFDPSSIDDETFEKNRKIYPKTPKQMDKITDILETIFFFNCLDEIQFSKIIQSMFFIEVFKGDEIIKENDPGNNFYVIDYGTF---TASNKSKSIYEVYKGEGFFGELALLYNCPRSASVIADTDGGLWVIDRVTFRQLILKSAYQKRQRYLKFISSVPLLEDLTKYEQCNLADALKTKTI-NNEKVISQGDAGDKMYFIXXXXXXXXXXXXXXXXXXSRLKAGDYFGEVALLANIPRIANVYALGYTKLAELDAKSYTRLLGPCIDNMRKNFTKYRSQLEKLLS 1197
LT++++ + +V P D++ +A YFT+ +E S D FDK SSE+ + ++ +++ K + + + E+++P DD+ E + I+PKT +Q ++ + + I F L+ +FS+++ +MF + V + II + D G+NFYVI+ G + + Y +G FGELAL+YN PR+A++IA G LW +DR TF +LI+++ +KR+ Y FI VPLL+ L E+ + D L K+ N E +I Q AG + E E +R G YFGE+AL+ N PR A+VYA+G TK +D +++ RLLGPC + M++N Y+ QL L
Sbjct: 9 LTDLLKGYTVEVLKQRPSDLLDFAVQYFTR--LKEQRSADVAFDKDTTPTESSEEDEEEEKEEEDEEEKEEDDDFPDDFTFKLCAEAYNPDDDDDDDSEP-KVIHPKTDQQRSRLQEACKDILLFKTLE--KFSEVLDAMFEVLVKPQEHIIDQGDDGDNFYVIERGVYDIVVGKDGVSRCVGKYDNKGSFGELALMYNTPRAATIIATQSGALWALDRATFHRLIVRNNAKKRRMYEAFIECVPLLKSLELSERMKIVDVLGAKSFKNGELIIKQTKAGQR---------------DNAEVEVARCSRGQYFGELALVTNKPRAASVYAVGETKCLVIDVQAFERLLGPCKEIMKRNIASYKEQLVALFG 359
BLAST of cAMP-dependent protein kinase type II regulatory subunit vs. Ensembl Cavefish
Match: prkar1ab (cAMP-dependent protein kinase type I-alpha regulatory subunit [Source:NCBI gene;Acc:103038385]) HSP 1 Score: 178.718 bits (452), Expect = 1.564e-51 Identity = 104/262 (39.69%), Postives = 156/262 (59.54%), Query Frame = 1
Query: 400 RKIYPKTPKQMDKITDILETIFFFNCLDEIQFSKIIQSMFFIEVFKGDEIIKENDPGNNFYVIDYGTFTASNKSKSIYEVYKGEGFFGELALLYNCPRSASVIADTDGGLWVIDRVTFRQLILKSAYQKRQRYLKFISSVPLLEDLTKYEQCNLADALKTKTI-NNEKVISQGDAGDKMYFIXXXXXXXXXXXXXXX--XXXSRLKAGDYFGEVALLANIPRIANVYALGYTKLAELDAKSYTRLLGPCIDNMRKNFTKYRS 1176
RK+ PK K M + +E F+ LD+ + S I +MF + G+ +I++ D G+NFYVID G ++ + +G G FGELAL+Y PR+A+V A T+ LW IDR ++R++++ S +KR+ Y +F+S V +LE L K+E+ +ADAL+ +++K++ QG+ GD+ + I EG V R E E E RL DYFGE+ALL N PR A V A G K +LD + R+LGPC D +++N +Y S
Sbjct: 113 RKVIPKDYKTMAALAKAIEKNVLFSHLDDNERSDIFDAMFPVTYIAGEIVIQQGDEGDNFYVIDQGEMDVYVNNEWATSIGEG-GSFGELALIYGTPRAATVRAKTNAKLWGIDRDSYRRILMGSTLRKRKMYEEFLSKVSILESLDKWERLTVADALEPVQFEDSQKIVVQGEPGDEFFIILEGCAAVLQRRSENEEFVEVGRLGPSDYFGEIALLMNRPRAATVVARGPLKCVKLDRPRFERVLGPCSDILKRNIQQYNS 373
BLAST of cAMP-dependent protein kinase type II regulatory subunit vs. Ensembl Cavefish
Match: prkar1b (protein kinase cAMP-dependent type I regulatory subunit beta [Source:NCBI gene;Acc:111191378]) HSP 1 Score: 176.792 bits (447), Expect = 1.052e-50 Identity = 104/262 (39.69%), Postives = 152/262 (58.02%), Query Frame = 1
Query: 400 RKIYPKTPKQMDKITDILETIFFFNCLDEIQFSKIIQSMFFIEVFKGDEIIKENDPGNNFYVIDYGTFTASNKSKSIYEVYKGEGFFGELALLYNCPRSASVIADTDGGLWVIDRVTFRQLILKSAYQKRQRYLKFISSVPLLEDLTKYEQCNLADALKTKTI-NNEKVISQGDAGDKMYFIXXXXXXXXXXXX--XXXXXXSRLKAGDYFGEVALLANIPRIANVYALGYTKLAELDAKSYTRLLGPCIDNMRKNFTKYRS 1176
RK+ PK K M + + F LD+ + S I +MF + G+ +I++ D G+NFYVID G + + + +G G FGELAL+Y PR+A+V A TD LW IDR ++R++++ S +KR+ Y +F+S V +LE L K+E+ +ADAL+ + EK++ QG+ GD + I EG V R EE E RL DYFGE+ALL N PR A V A G K +LD + R+LGPC + +++N +Y S
Sbjct: 116 RKVIPKDYKTMTALAKAISKNVLFAHLDDNERSDIFDAMFPVTHIAGETVIQQGDEGDNFYVIDQGEVDVYVNGEWVTGIGEG-GSFGELALIYGTPRAATVKAKTDLKLWGIDRDSYRRILMGSTLRKRKMYEEFLSKVSILESLEKWERLTVADALEPVQFEDGEKIVVQGEPGDDFFIITEGTASVLQRRSDNEEYVEVGRLGPSDYFGEIALLLNRPRAATVVARGPLKCVKLDRPRFERVLGPCSEILKRNIQRYNS 376
BLAST of cAMP-dependent protein kinase type II regulatory subunit vs. Ensembl Sea Lamprey
Match: prkar2aa (protein kinase, cAMP-dependent, regulatory, type II, alpha A [Source:ZFIN;Acc:ZDB-GENE-030131-1007]) HSP 1 Score: 158.688 bits (400), Expect = 2.350e-46 Identity = 83/196 (42.35%), Postives = 119/196 (60.71%), Query Frame = 1
Query: 640 YKGEGFFGELALLYNCPRSASVIADTDGGLWVIDRVTFRQLILKSAYQKRQRYLKFISSVPLLEDLTKYEQCNLADALKTKTI-NNEKVISQG---------DAGDKMYFIXXXXXXXXXXXXXXXXXXSRLKAGDYFGEVALLANIPRIANVYALGYTKLAELDAKSYTRLLGPCIDNMRKNFTKYRSQLEKLLS 1197
Y G FGELAL+YN PR+A+++A T+G LW +DR TFR++ILK+A QKR+ Y FI SVPLL+ L E+ + D + TK+ + E++I+QG +AG+ ++ T E E E +R G YFGE++L+ N PR A+ YA+G K A + + + RLLGPC+D M++N T Y QL L
Sbjct: 20 YDNRGSFGELALMYNTPRAATIVATTEGSLWAMDRATFRRIILKNAAQKRKMYEAFIESVPLLKSLDASERMKVVDTITTKSYEDGEQIIAQGAKADCFFIVEAGEVRIMMKSKTQPPAETTKEGEVEIARCTRGQYFGELSLVTNKPRAASAYAVGNVKCAVMGVQPFERLLGPCMDIMKRNITHYEEQLVALFG 215
BLAST of cAMP-dependent protein kinase type II regulatory subunit vs. Ensembl Sea Lamprey
Match: si:ch211-272n13.7 (protein kinase cAMP-dependent type II regulatory subunit beta [Source:HGNC Symbol;Acc:HGNC:9392]) HSP 1 Score: 149.443 bits (376), Expect = 8.188e-42 Identity = 91/307 (29.64%), Postives = 164/307 (53.42%), Query Frame = 1
Query: 97 LTEVIEEFKKQVEIANPKDIIAYAATYFTKKVAQENESNDTEFDKSLD-YDSSSEDGDSLKE--IMSNDKSKMKL------------------VQTSNVPRQSITCESFDPSSIDDETFEKNRKIYPKTPKQMDKITDILETIFFFNCLDEIQFSKIIQSMFFIEVFKGDEIIKENDPGNNFYVIDYGTF---TASNKSKSIYEVYKGEGFFGELALLYNCPRSASVIADTDGGLWVIDRVTFRQLILKSAYQKRQRYLKFISSVPLLEDLTKYEQCNLADALKTKTI-NNEKVISQGDAGDKMYFI 942
LTE+++ F +V + P D++ +AA YF + + E + D +D + G + E + + + V + R S+ E+++P +++T + R I+PKT +Q +++ + + I F LD+ Q S+++ +MF V G+ +I + G+NFYVI+ G + +N Y G FGELAL+YN R+A++IA ++G LW +DR+TFR++I+K+A +KR+ Y FI +VPLL+ L E+ + D + +K+ ++E++I+QG+ D Y +
Sbjct: 9 LTELLQAFTVEVLRSRPADLLDFAAAYFAEMRQRARERCGAPAQQLADGFDDAHGRGVNFSEENVAGHSSNSDNNGDDDRDDDDDDESDFEAPVISRFTRRASVCAEAYNPDEEEEDT--ETRVIHPKTDEQRNRLQEACKHILIFKNLDQEQMSQVLDAMFEKTVETGEHVIDQGADGDNFYVIERGMYDIYVTTNDVSRCVGAYNNRGSFGELALMYNTSRAATIIATSEGALWGLDRLTFRRIIVKNAAKKRKMYECFIETVPLLKSLDFSERLKVVDVIASKSFQDSERIIAQGEKADCFYLV 313
BLAST of cAMP-dependent protein kinase type II regulatory subunit vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001198.1 (pep scaffold:Pmarinus_7.0:GL480445:10050:25657:1 gene:ENSPMAG00000001068.1 transcript:ENSPMAT00000001198.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 91.2781 bits (225), Expect = 1.365e-20 Identity = 61/221 (27.60%), Postives = 108/221 (48.87%), Query Frame = 1
Query: 454 ETIFFFNCLDEIQFSKIIQSMFFIEVFKGDEIIKENDPGNNFYVIDYGTFTASNKSKSIYEVYKGEGFFGELALLYNCPRSASVIADTDGGLWVIDRVTFRQLILKSAYQKRQRYLKFISSVPLLEDLTKYEQCNLADALKTKTI-NNEKVISQGDAGDKMYFIXXXXXXXXXXXXXXXXXXSRLKAGDYFGEVALLANIPRIANVYALGYTKLAELDAKS 1113
+T+ +C+ E ++ G+ II E D V G S + +S+ + G FGELA+LY+C R+A+V A TD L + R FR ++++ + +R+ +KF+ + L++L + + D ++ + E ++++G+ G Y I G+V V+ R L+ GD+FGE+AL+ N+ R A A+G L +S
Sbjct: 20 QTVLLGDCMSETTRAR------------GETIIAEGDSSRRLKVDVEGLLDVSKQGESLCTLQPG-ALFGELAILYDCTRTATVKALTDVRLLYLSRHAFRSVLMRESQLRRKLIIKFLKTAKTLKNLPDEQLSKMFDCMEESAFADGEAIVNEGEVGHIFYVILRGQVRVSQEVEGSPRLIRVLEPGDHFGELALIRNMRRTATCTAVGAVTCLTLHTRS 227
BLAST of cAMP-dependent protein kinase type II regulatory subunit vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001825.1 (pep scaffold:Pmarinus_7.0:GL485714:520:7294:-1 gene:ENSPMAG00000001656.1 transcript:ENSPMAT00000001825.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 79.337 bits (194), Expect = 7.693e-17 Identity = 36/132 (27.27%), Postives = 71/132 (53.79%), Query Frame = 1
Query: 415 KTPKQMDKITDILETIFFFNCLDEIQFSKIIQSMFFIEVFKGDEIIKENDPGNNFYVIDYGTFTASNKSKSIYEVYKGEGFFGELALLYNCPRSASVIADTDGGLWVIDRVTFRQLILKSAYQKRQRYLKFI 810
K P I L F L++ + +++++ M+ +I+E + GN+ YV+ + + + ++ G FGELA+LYNC R+A+V A T +WV+DR+TF+ ++++ + Q +++F+
Sbjct: 163 KNPCSQRLIKAALAKNEFLRRLEDGRVARMVECMYERAYSPEQAVIREGEAGNHLYVLAAASLDCQQRGTCLGHMHPGT-VFGELAILYNCKRTATVKAVTAVRVWVLDRLTFQAIVIREEQARHQEHVRFL 293
BLAST of cAMP-dependent protein kinase type II regulatory subunit vs. Ensembl Sea Lamprey
Match: ENSPMAT00000005026.1 (pep scaffold:Pmarinus_7.0:GL484567:1893:8879:-1 gene:ENSPMAG00000004571.1 transcript:ENSPMAT00000005026.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 63.929 bits (154), Expect = 3.765e-13 Identity = 29/59 (49.15%), Postives = 43/59 (72.88%), Query Frame = 1
Query: 652 GFFGELALLYNCPRSASVIADTDGGLWVIDRVTFRQLILKSAYQKRQRYLKFISSVPLL 828
G FGELAL+Y PR+A+V A TD LW IDR ++R++++ S +KR+ Y +F+S V +L
Sbjct: 37 GSFGELALIYGTPRAATVKAKTDLKLWGIDRDSYRRILMGSTLRKRKMYEEFLSKVSIL 95
BLAST of cAMP-dependent protein kinase type II regulatory subunit vs. Ensembl Yeast
Match: BCY1 (Regulatory subunit of the cyclic AMP-dependent protein kinase (PKA); PKA is a component of a signaling pathway that controls a variety of cellular processes, including metabolism, cell cycle, stress response, stationary phase, and sporulation [Source:SGD;Acc:S000001295]) HSP 1 Score: 175.252 bits (443), Expect = 1.074e-50 Identity = 107/280 (38.21%), Postives = 162/280 (57.86%), Query Frame = 1
Query: 334 RQSITCESFDPSSIDDETFEKNRKIYPKTPKQMDKITDILETIFFFNCLDEIQFSKIIQSMFFIEVFKGDEIIKENDPGNNFYVIDYGT---FTASNKSKSIYEVYKGEGF-FGELALLYNCPRSASVIADTDGGLWVIDRVTFRQLILKSAYQKRQRYLKFISSVPLLEDLTKYEQCNLADALKTKTIN-NEKVISQGDAGDKMYFIXXXXXXXXXXXXXXXXXXSRLKAGDYFGEVALLANIPRIANVYALGYTKLAELDAKSYTRLLGPCIDNMRKN 1158
R S++ E+ P++ DD T + ++ K+ +Q+ ++ + F FN LD +I + V KG IIK+ D G+ FYV++ GT + NK S G G FGELAL+YN PR+A+V+A +D LW +DR+TFR+++L S+++KR Y + S+P+L+ LT Y++ LADAL TK E +I +GD G+ Y I E + + + ++LK DYFGEVALL ++PR A V A TK+A L + RLLGP +D ++ N
Sbjct: 143 RTSVSGETLQPNNFDDWTPDHYKE---KSEQQLQRLEKSIRNNFLFNKLDSDSKRLVINCLEEKSVPKGATIIKQGDQGDYFYVVEKGTVDFYVNDNKVNS-----SGPGSSFGELALMYNSPRAATVVATSDCLLWALDRLTFRKILLGSSFKKRLMYDDLLKSMPVLKSLTTYDRAKLADALDTKIYQPGETIIREGDQGENFYLI---EYGAVDVSKKGQGVINKLKDHDYFGEVALLNDLPRQATVTATKRTKVATLGKSGFQRLLGPAVDVLKLN 411
BLAST of cAMP-dependent protein kinase type II regulatory subunit vs. Ensembl Nematostella
Match: EDO38262 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SDH8]) HSP 1 Score: 226.868 bits (577), Expect = 3.247e-70 Identity = 131/378 (34.66%), Postives = 217/378 (57.41%), Query Frame = 1
Query: 97 LTEVIEEFKKQVEIANPKDIIAYAATYFTKKVAQENESNDTEFDKSLDYDSSSEDGDSLKEIMSNDKSKMKLVQTSN--VPRQSITCESFDPSSIDDETFEKNRKIYPKTPKQMDKITDILETIFFFNCLDEIQFSKIIQSMFFIEVFKGDEIIKENDPGNNFYVIDYGTF---TASNKSKSIYEVYKGEGFFGELALLYNCPRSASVIADTDGGLWVIDRVTFRQLILKSAYQKRQRYLKFISSVPLLEDLTKYEQCNLADALKTKTI-NNEKVISQGDAGDKMYFIXXXXXXXXXXXXXXXXXX---SRLKAGDYFGEVALLANIPRIANVYALGYTKLAELDAKSYTRLLGPCIDNMRKNFTKYRSQLEKLLSRH 1203
L++++++F V P+DI+ +AA YF K +E S + S G+ + + D+ N RQS+ E F P S D+ ++ +YPKT +Q ++ D ++ I F L + Q ++++ +MF + GD II + D G+NFYVID G + + + + Y +G FGELAL+YN PR+A++++ ++G +W +DR+TFR+++LK+A +KR+ + + +VPLL+++T+YE+ NLADAL ++ + E +I QGD D MYF+E G V + + + E ++ G YFGE+AL+ + R A+VY++G A LD ++ RLLGPC+D M++N Y QL+KL H
Sbjct: 9 LSDLLQDFTVHVLREKPEDIVDFAANYFMKLKLKEKRSQKGKKKNKEKGVSFGPPGNDEDDTYNEDEDDEMPEPPKNRYARRQSVCAEPFHPDSEDE--GDEQPIVYPKTDEQRQRLNDAIKNILLFKNLAKEQLNEVLDAMFERKTQAGDHIIDQGDDGDNFYVIDRGQYDIYVRIDGQEKMVGSYDNKGSFGELALMYNTPRAATIVSTSEGVIWGLDRMTFRRILLKAAAKKRKVHEALLETVPLLQEITEYERMNLADALVSRQFKDGECIIKQGDEADFMYFVESGTVSIRMHNKSDPTTEVEIAQCTKGGYFGELALITHNTRAASVYSVGDCVCASLDVHAFERLLGPCMDIMKRNIDGYEEQLQKLGVEH 384
BLAST of cAMP-dependent protein kinase type II regulatory subunit vs. Ensembl Nematostella
Match: EDO48439 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RJW7]) HSP 1 Score: 182.956 bits (463), Expect = 1.381e-53 Identity = 105/270 (38.89%), Postives = 159/270 (58.89%), Query Frame = 1
Query: 376 DDETFEKNRKIYPKTPKQMDKITDILETIFFFNCLDEIQFSKIIQSMFFIEVFKGDEIIKENDPGNNFYVIDYGTFTASNKSKSIYEVYKGEGFFGELALLYNCPRSASVIADTDGGLWVIDRVTFRQLILKSAYQKRQRYLKFISSVPLLEDLTKYEQCNLADALK-TKTINNEKVISQGDAGDKMYFIXXXXXXXXXXXXXXX--XXXSRLKAGDYFGEVALLANIPRIANVYALGYTKLAELDAKSYTRLLGPCIDNMRKNFTKYRS 1176
+DE +K+ PK K M ++ + F+ LDE + S I +M ++ G+ IIK+ D G+NFY++D G + + G FGELAL+Y PR+A++ A TD LW IDRVT+R++++ S +KR+ Y +F+ V +LE L K+E+ +ADAL+ T+ + + V+ QG+ GD+ + I EG +V R E E SRL DYFGE+AL+ N PR A V A G K +LD + + R+LGPCID +++N +Y S
Sbjct: 100 EDEATSYVKKVVPKDYKTMAALSKAITKNILFSHLDENERSDIFDAMSLVKHGAGEIIIKQGDEGDNFYIVDSGEVDVFVNNVGLVSTIGEGGSFGELALIYGTPRAATIKAKTDVKLWAIDRVTYRRILMGSQIRKRRMYEQFLEKVSILESLDKWERLTVADALEPTQFQDGDDVVVQGEHGDEFFIIVEGTAVVLQRRSANEDFIEVSRLGPSDYFGEIALVLNRPRAATVQARGTLKCVKLDRQRFERVLGPCIDILKRNIQQYNS 369
BLAST of cAMP-dependent protein kinase type II regulatory subunit vs. Ensembl Nematostella
Match: EDO49534 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RGJ3]) HSP 1 Score: 182.57 bits (462), Expect = 2.258e-53 Identity = 120/379 (31.66%), Postives = 200/379 (52.77%), Query Frame = 1
Query: 97 LTEVIEEFKKQVEIANPKDIIAYAATYFTK------KVAQENESNDTEFDKSLDYDSSSEDGDSLKEIMSNDKSKMKLVQTSNVPRQSITCESFDPSSIDDETFEKNRKIYPKTPKQMDKITDILETIFFFNCLDEIQFSKIIQSMFFIEVFKGDEIIKENDPGNNFYVIDYGTFTA---SNKSKSIYEVYKGEGFFGELALLYNCPRSASVIADTDGGLWVIDRVTFRQLILKSAYQKRQRYLKFISSVPLLEDLTKYEQCNLADALKTKTINNEK-VISQGDAGDKMYFIXXXXXXXX---XXXXXXXXXXSRLKAGDYFGEVALLANIPRIANVYAL-GYTKLAELDAKSYTRLLGPCIDNMRKNFTKYRSQLEKL 1191
L ++++ F V P D++ +AA+YF+K + + + E D +S S D K ++ L R S+ E ++P ++ R YPK+ ++ +++ IF F + Q + ++ +M+ V++ + II++ D G+NFY+ID G F +N ++ KG G FGELAL+YNCPRSA++ A T G LWV+DR +FR++++ + +KR+ Y + +P+L LT YE+ +LADAL T +E+ +I Q D D +YFIE G V ++ + + + S G+YFGE+AL+ R A+V+A G A L+ ++ RLLGPC M++N Y + + L
Sbjct: 10 LHKLLQSFILDVFTEQPDDLVDFAASYFSKLNTSRKPIHSSSTPSTQEEDDFYCSESLSLPSDRFKRPSYQQNHRLYLR------RDSVAGEVYEP--VNSNCVSAQR-FYPKSEDARKRLENVIGNIFIFKSCGKDQINMMLDAMYERVVYQEETIIRQGDAGDNFYIIDEGEFEVLFETNGAQEKLGRLKGPGSFGELALMYNCPRSATIRACTPGVLWVLDRKSFRRILVDTTERKRRHYETLLERIPVLSQLTAYERTSLADALTTSVYRDEECIIRQDDPADCLYFIESGIVEISIRDSKDRSKVKVISTAGPGEYFGELALVNKTKRGASVHAKGGQVTCAVLEVNAFERLLGPCKGLMQRNMKTYEEERKCL 379
BLAST of cAMP-dependent protein kinase type II regulatory subunit vs. Ensembl Nematostella
Match: EDO41163 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S513]) HSP 1 Score: 166.007 bits (419), Expect = 2.732e-47 Identity = 128/373 (34.32%), Postives = 210/373 (56.30%), Query Frame = 1
Query: 97 LTEVIEEFKKQVEIANPKDIIAYAATYFTK-KVAQENESNDTEFDKSLDYDSSSEDGDSLKEIMSNDKSKMKLVQTSNVPRQSITCESFDPSSIDDETFEKNRKIYPKTPKQMDKITDILETIFFFNCLDEIQFSKIIQSMFFIEVFKGDEIIKENDPGNNFYVIDYGTFTA----SNKSKSI-YEVYKGEGFFGELALLYNCPRSASVIADTDGGLWVIDRVTFRQLILKSAYQKRQRYLKFISSVPLLEDLTKYEQCNLADALKTKTI-NNEKVISQG-DAGDKMYFIXXXXXXXXXXXXXXXXXXSRLKAGDYFGEVALLANIPRIANVYALGYTKLAELDAKSYTRLLGPCIDNMRKNFTKYRSQLEKL 1191
L+ ++EEF + NP+DI+ +AA YF K +E ++ + +S SED D L ++ +++ + R +++ E ++P +E + K +PK+ +Q + + L ++ F I+ SMF +V + IIK D G+NFYVI+ G + +N SI + G G FGELAL++N R+A+++A T+G LW +DR TF Q+++ A ++R+R ++ + SV +L++L E ++DAL K + E VI +G ++ MYFIE+G+V VTV+ GE E+ K +YFGE+AL+ N PR A+VYA+G K A L + RL+GPC + M++N +Y Q +KL
Sbjct: 13 LSSLLEEFVVKCIQENPEDIVEFAADYFNMLKRFKEKKAASKQAAQS---KKESEDKDDLA------PAEQPIIKGRSR-RAAVSAEPYNP----NENADFKAKFHPKSEEQRNHLKKKLLELWLFEKFHREDLDVILDSMFEKKVSPEEIIIKVGDEGDNFYVINTGEYDVFALDTNTGASIKVHTFNGTGMFGELALMHNSLRNATIVAKTEGTLWALDRSTFVQVVVGGAQRRRERNIELLKSVSILKELKPDELDKVSDALYPKEFKDGEAVIREGNESAYCMYFIEKGKVRVTVKDGEVEKTVEFDK--NYFGELALVMNQPRSASVYAVGECKFASLKKDDFERLMGPCKEIMKRNAKEYEEQKKKL 369
BLAST of cAMP-dependent protein kinase type II regulatory subunit vs. Ensembl Nematostella
Match: EDO38399 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SCY8]) HSP 1 Score: 118.242 bits (295), Expect = 1.264e-28 Identity = 87/261 (33.33%), Postives = 136/261 (52.11%), Query Frame = 1
Query: 301 KMKLVQTSNVPRQSITCESFDPSSIDDETFEKNRKIYPKTPKQMDKITDILETIFFFNCLDEIQFSKIIQSMFFIEVFKGDEIIKENDPGNNFYVIDYGTFTASNKSKSIYEVYKGEGFFGELALLYNCPRSASVIADTDGGLWVIDRVTFRQLILKSAYQKRQRYLKFISSVPLLEDLTKYEQCNLADALKTKTIN-NEKVISQGDAGDKMYFIXXXXXXXXXXXXXXX--XXXSRLKAGDYFGEVALLANIPRIANVYA 1074
K KL + RQ+++ ES + + T K + +PK + I D + F L+ Q +I+ M+ + D II+E D GN Y I G + ++K + E+ G FGELA+LYNC R+A+V A LW IDR F+ +++++ ++ ++ F+ SVPLL++L E LAD L+ + + +I + + GD Y I +G VT R + +E +L+ GDYFGE ALL+ R ANV A
Sbjct: 11 KKKLRPSKKEKRQAVSGESSTKAQEESRT-GKELERFPKDFRSKQLIKDAIFENDFLKNLEAAQVREIVDCMYSNTFQRNDVIIQEGDAGNALYAIADGRLQVTRENKVLGEMVAGM-VFGELAILYNCRRTATVTAMEPTKLWKIDRRVFQIIMMRTGMIRQAEHMAFLKSVPLLKELPNAELSKLADVLEVDFYHAGDYIIRENERGDTFYIITKGSARVTQRIEGQTGPKEIRKLQKGDYFGEKALLSEDRRTANVIA 269 HSP 2 Score: 50.8322 bits (120), Expect = 6.905e-7 Identity = 36/112 (32.14%), Postives = 59/112 (52.68%), Query Frame = 1
Query: 451 LETIFFFNCLDEIQFSKIIQSMFFIEVFKGDEIIKENDPGNNFYVIDYGTFTASNK------SKSIYEVYKGEGFFGELALLYNCPRSASVIADTDG-GLWVIDRVTFRQLI 765
L+++ L + SK+ + GD II+EN+ G+ FY+I G+ + + K I ++ KG+ +FGE ALL R+A+VIA+ +G V+DR F +I
Sbjct: 178 LKSVPLLKELPNAELSKLADVLEVDFYHAGDYIIRENERGDTFYIITKGSARVTQRIEGQTGPKEIRKLQKGD-YFGEKALLSEDRRTANVIAEENGVECLVVDRTVFMTVI 288
BLAST of cAMP-dependent protein kinase type II regulatory subunit vs. Ensembl Medaka
Match: si:ch211-272n13.7 (protein kinase cAMP-dependent type II regulatory subunit beta [Source:NCBI gene;Acc:101166375]) HSP 1 Score: 218.779 bits (556), Expect = 1.585e-66 Identity = 135/397 (34.01%), Postives = 218/397 (54.91%), Query Frame = 1
Query: 97 LTEVIEEFKKQVEIANPKDIIAYAATYFTKKVAQENESNDTEFDKSLDYDSSSEDGDSLK---EIMSNDKSK---------------MKLVQTSNVPRQSITCESFDPSSIDDETFEKNRKIYPKTPKQMDKITDILETIFFFNCLDEIQFSKIIQSMFFIEVFKGDEIIKENDPGNNFYVIDYGTFTASNKSKSIYEV---YKGEGFFGELALLYNCPRSASVIADTDGGLWVIDRVTFRQLILKSAYQKRQRYLKFISSVPLLEDLTKYEQCNLADALKTKTINN-EKVISQGDAGDKMYFIXXXXXXXXXXXXXXX--------XXXSRLKAGDYFGEVALLANIPRIANVYALGYTKLAELDAKSYTRLLGPCIDNMRKNFTKYRSQLEKLLS 1197
LTE+++ F +V P+D++ +A YFT+ ++NE+ + F D +S+ G ++ E M D + V + R S+ E+F+P +DE ++ R YPKT +Q ++ + I F LD + S+++ +MF +G+ II ++D G+NFYVI+ GTF K I ++ Y G FGELAL+YN PR+A++IA + G LW +DR+TFR++I+K+ +KR+ Y FI ++PLL L E+ + D L T+ N+ +++I+QGD D Y +E G+V +T++ E + G YFGE+AL+ N PR A+ YA+G K +D +++ RLLGPC+D M++N Y QL+ L
Sbjct: 9 LTELLQSFTVEVLRNQPRDLLEFALQYFTQ--LKDNETKEAAFGN--DQNSAPRSGKAVNFIDEAMQIDSENGEEEEDDDDDDDEEFIAPVINRFIRRASVCAEAFNPD--EDEEDKEPRVTYPKTDEQRQRLQEACRDILLFKNLDPEEISQVLDAMFEKFCTEGEHIIDQDDDGDNFYVIESGTFNIFVKVDGIEKLVGCYDNRGSFGELALMYNTPRAATIIATSPGALWCLDRLTFRRIIVKNNAKKRRLYEAFIETLPLLTSLETSERMKVVDVLSTRVYNDSQQIIAQGDLADCFYIVESGQVRITMKRSRMTKKDQEEEEVEIATCTRGQYFGELALVTNKPRAASAYAVGSVKCLVMDVQAFERLLGPCMDIMKRNIANYEEQLQSLFG 399
BLAST of cAMP-dependent protein kinase type II regulatory subunit vs. Ensembl Medaka
Match: prkar2aa (cAMP-dependent protein kinase type II-alpha regulatory subunit [Source:NCBI gene;Acc:101159349]) HSP 1 Score: 206.453 bits (524), Expect = 5.278e-62 Identity = 125/379 (32.98%), Postives = 205/379 (54.09%), Query Frame = 1
Query: 97 LTEVIEEFKKQVEIANPKDIIAYAATYFTK---KVAQENESNDTEFDKSLDYDSSSEDGDSLKEIMSNDKSKMKLVQTSNVPRQ-SITCESFDPSSIDDETFEKNRKIYPKTPKQMDKITDILETIFFFNCLDEIQFSKIIQSMFFIEVFKGDEIIKENDPGNNFYVIDYGTFTASNKSKSIYEVYKGEGFFGELALLYNCPRSASVIADTDGGLWVIDRVTFRQLILKSAYQKRQRYLKFISSVPLLEDLTKYEQCNLADALKTKT-INNEKVISQGDAGDKMYF-------IXXXXXXXXXXXXXXXXXXSRLKAGDYFGEVALLANIPRIANVYALGYTKLAELDAKSYTRLLGPCIDNMRKNFTKYRSQLEKLLS 1197
LTE+++ + +V P D++ +A YFT+ Q+ + K + +D +S + +D S + S R+ S+ E+F+P D++T + R ++PKT +Q ++ + I F LD+ QFS+++ +MF ++V + +I + G+NFYVI+ G + K + + Y +G FGELAL+YN PR+A++IA +G LW +DR TFR+LI+K+ +KR+ Y FI SVPLL+ L E+ + D L K ++ E++I+QG+ + Y I E E +R G YFGE+AL+ N PR A+ YA+G K +D +++ RLLG C + M++N + Y QL L
Sbjct: 9 LTELLQGYTVEVLRQRPSDLVEFAVQYFTRLRDSRGQDGAGTGAKQGKGVMFDGEPMQTESNGDDEEDDDSDFEPPPPSRFNRRVSVCAEAFNPDDDDEDT--EPRVVHPKTDEQRCRLQEACRDILLFKTLDQEQFSQVLDAMFELKVQPQEHVIDQGHDGDNFYVIERGIYDIVVSGKCVGQ-YNNKGSFGELALMYNTPRAATIIATQEGALWGLDRATFRRLIVKNNAKKRRMYETFIESVPLLKTLEPNERMKIVDVLGMKQFLDGERIIAQGEKAECFYIVESGEVKIMMKSKTKADHADNAEVEITRCSRGQYFGELALVTNKPRAASAYAVGDVKCLVIDVQAFERLLGSCKEIMKRNISHYEEQLVALFG 384
BLAST of cAMP-dependent protein kinase type II regulatory subunit vs. Ensembl Medaka
Match: prkar2aa (cAMP-dependent protein kinase type II-alpha regulatory subunit [Source:NCBI gene;Acc:101159349]) HSP 1 Score: 199.904 bits (507), Expect = 1.032e-59 Identity = 123/372 (33.06%), Postives = 201/372 (54.03%), Query Frame = 1
Query: 97 LTEVIEEFKKQVEIANPKDIIAYAATYFTK---KVAQENESNDTEFDKSLDYDSSSEDGDSLKEIMSNDKSKMKLVQTSNVPRQ-SITCESFDPSSIDDETFEKNRKIYPKTPKQMDKITDILETIFFFNCLDEIQFSKIIQSMFFIEVFKGDEIIKENDPGNNFYVIDYGTFTASNKSKSIYEVYKGEGFFGELALLYNCPRSASVIADTDGGLWVIDRVTFRQLILKSAYQKRQRYLKFISSVPLLEDLTKYEQCNLADALKTKT-INNEKVISQGDAGDKMYFIXXXXXXXXXXXXXXXXXXSRLKAGDYFGEVALLANIPRIANVYALGYTKLAELDAKSYTRLLGPCIDNMRKNFTKYRSQLEKLLS 1197
LTE+++ + +V P D++ +A YFT+ Q+ + K + +D +S + +D S + S R+ S+ E+F+P D++T + R ++PKT +Q ++ + I F LD+ QFS+++ +MF ++V + +I + G+NFYVI+ G + K + + Y +G FGELAL+YN PR+A++IA +G LW +DR TFR+LI+K+ +KR+ Y FI SVPLL+ L E+ + D L K ++ E++I+Q A E E +R G YFGE+AL+ N PR A+ YA+G K +D +++ RLLG C + M++N + Y QL L
Sbjct: 9 LTELLQGYTVEVLRQRPSDLVEFAVQYFTRLRDSRGQDGAGTGAKQGKGVMFDGEPMQTESNGDDEEDDDSDFEPPPPSRFNRRVSVCAEAFNPDDDDEDT--EPRVVHPKTDEQRCRLQEACRDILLFKTLDQEQFSQVLDAMFELKVQPQEHVIDQGHDGDNFYVIERGIYDIVVSGKCVGQ-YNNKGSFGELALMYNTPRAATIIATQEGALWGLDRATFRRLIVKNNAKKRRMYETFIESVPLLKTLEPNERMKIVDVLGMKQFLDGERIIAQTKA---------------DHADNAEVEITRCSRGQYFGELALVTNKPRAASAYAVGDVKCLVIDVQAFERLLGSCKEIMKRNISHYEEQLVALFG 362
BLAST of cAMP-dependent protein kinase type II regulatory subunit vs. Ensembl Medaka
Match: si:ch211-272n13.7 (protein kinase cAMP-dependent type II regulatory subunit beta [Source:NCBI gene;Acc:101166375]) HSP 1 Score: 200.675 bits (509), Expect = 1.364e-59 Identity = 134/397 (33.75%), Postives = 216/397 (54.41%), Query Frame = 1
Query: 97 LTEVIEEFKKQVEIANPKDIIAYAATYFTKKVAQENESNDTEFDKSLDYDSSSEDGDSLK---EIMSNDKSK---------------MKLVQTSNVPRQSITCESFDPSSIDDETFEKNRKIYPKTPKQMDKITDILETIFFFNCLDEIQFSKIIQSMFFIEVFKGDEIIKENDPGNNFYVIDYGTFTASNKSKSIYEV---YKGEGFFGELALLYNCPRSASVIADTDGGLWVIDRVTFRQLILKSAYQKRQRYLKFISSVPLLEDLTKYEQCNLADALKTKTINN-EKVISQGDAGDKMYFIXXXXXXXXXXXXXXX--------XXXSRLKAGDYFGEVALLANIPRIANVYALGYTKLAELDAKSYTRLLGPCIDNMRKNFTKYRSQLEKLLS 1197
LTE+++ F +V P+D++ +A YFT+ ++NE+ + F D +S+ G ++ E M D + V + R S+ E+F+P +DE ++ R+ + K+ DIL F F +EI S+++ +MF +G+ II ++D G+NFYVI+ GTF K I ++ Y G FGELAL+YN PR+A++IA + G LW +DR+TFR++I+K+ +KR+ Y FI ++PLL L E+ + D L T+ N+ +++I+QGD D Y +E G+V +T++ E + G YFGE+AL+ N PR A+ YA+G K +D +++ RLLGPC+D M++N Y QL+ L
Sbjct: 9 LTELLQSFTVEVLRNQPRDLLEFALQYFTQ--LKDNETKEAAFGN--DQNSAPRSGKAVNFIDEAMQIDSENGEEEEDDDDDDDEEFIAPVINRFIRRASVCAEAFNPD--EDEEDKEPRRGFKFVSSPQPKMFDIL---FIFQ--EEI--SQVLDAMFEKFCTEGEHIIDQDDDGDNFYVIESGTFNIFVKVDGIEKLVGCYDNRGSFGELALMYNTPRAATIIATSPGALWCLDRLTFRRIIVKNNAKKRRLYEAFIETLPLLTSLETSERMKVVDVLSTRVYNDSQQIIAQGDLADCFYIVESGQVRITMKRSRMTKKDQEEEEVEIATCTRGQYFGELALVTNKPRAASAYAVGSVKCLVMDVQAFERLLGPCMDIMKRNIANYEEQLQSLFG 392
BLAST of cAMP-dependent protein kinase type II regulatory subunit vs. Ensembl Medaka
Match: prkar1b (protein kinase cAMP-dependent type I regulatory subunit beta [Source:NCBI gene;Acc:101155602]) HSP 1 Score: 176.792 bits (447), Expect = 8.519e-51 Identity = 103/262 (39.31%), Postives = 152/262 (58.02%), Query Frame = 1
Query: 400 RKIYPKTPKQMDKITDILETIFFFNCLDEIQFSKIIQSMFFIEVFKGDEIIKENDPGNNFYVIDYGTFTASNKSKSIYEVYKGEGFFGELALLYNCPRSASVIADTDGGLWVIDRVTFRQLILKSAYQKRQRYLKFISSVPLLEDLTKYEQCNLADALKTKTI-NNEKVISQGDAGDKMYFIXXXXXXXXXXXXXXX--XXXSRLKAGDYFGEVALLANIPRIANVYALGYTKLAELDAKSYTRLLGPCIDNMRKNFTKYRS 1176
RK+ PK K M + + F LD+ + S I +MF + G+ +I++ D G+NFYVID G + + + +G G FGELAL+Y PR+A+V A TD LW IDR ++R++++ S +KR+ Y +F+S V +LE L K+E+ +ADAL+ + EK++ QG+ GD + I EG V R + E E RL DYFGE+ALL N PR A V A G K +LD + R+LGPC + +++N +Y S
Sbjct: 114 RKVIPKDYKTMTALAKAISKNVLFAHLDDNERSDIFDAMFPVTHIAGETVIQQGDEGDNFYVIDQGEVDVYVNGELVTNIGEG-GSFGELALIYGTPRAATVKAKTDLKLWGIDRDSYRRILMGSTLRKRKMYEEFLSKVSILESLDKWERLTVADALEPVQFEDGEKIVVQGEPGDDFFIITEGIASVLQRRSDNEEYVEVGRLGPSDYFGEIALLLNRPRAATVVARGPLKCVKLDRPRFERVLGPCSEILKRNIQRYNS 374
BLAST of cAMP-dependent protein kinase type II regulatory subunit vs. Planmine SMEST
Match: SMESG000051354.1 (SMESG000051354.1) HSP 1 Score: 753.051 bits (1943), Expect = 0.000e+0 Identity = 389/390 (99.74%), Postives = 389/390 (99.74%), Query Frame = 1
Query: 67 MNNQNYSKKILTEVIEEFKKQVEIANPKDIIAYAATYFTKKVAQENESNDTEFDKSLDYDSSSEDGDSLKEIMSNDKSKMKLVQTSNVPRQSITCESFDPSSIDDETFEKNRKIYPKTPKQMDKITDILETIFFFNCLDEIQFSKIIQSMFFIEVFKGDEIIKENDPGNNFYVIDYGTFTASNKSKSIYEVYKGEGFFGELALLYNCPRSASVIADTDGGLWVIDRVTFRQLILKSAYQKRQRYLKFISSVPLLEDLTKYEQCNLADALKTKTINNEKVISQGDAGDKMYFIXXXXXXXXXXXXXXXXXXSRLKAGDYFGEVALLANIPRIANVYALGYTKLAELDAKSYTRLLGPCIDNMRKNFTKYRSQLEKLLSRHQLEELFPELIN 1236
MNNQNYS KILTEVIEEFKKQVEIANPKDIIAYAATYFTKKVAQENESNDTEFDKSLDYDSSSEDGDSLKEIMSNDKSKMKLVQTSNVPRQSITCESFDPSSIDDETFEKNRKIYPKTPKQMDKITDILETIFFFNCLDEIQFSKIIQSMFFIEVFKGDEIIKENDPGNNFYVIDYGTFTASNKSKSIYEVYKGEGFFGELALLYNCPRSASVIADTDGGLWVIDRVTFRQLILKSAYQKRQRYLKFISSVPLLEDLTKYEQCNLADALKTKTINNEKVISQGDAGDKMYFIEEGEVLVTVRTGEEEREESRLKAGDYFGEVALLANIPRIANVYALGYTKLAELDAKSYTRLLGPCIDNMRKNFTKYRSQLEKLLSRHQLEELFPELIN
Sbjct: 1 MNNQNYSNKILTEVIEEFKKQVEIANPKDIIAYAATYFTKKVAQENESNDTEFDKSLDYDSSSEDGDSLKEIMSNDKSKMKLVQTSNVPRQSITCESFDPSSIDDETFEKNRKIYPKTPKQMDKITDILETIFFFNCLDEIQFSKIIQSMFFIEVFKGDEIIKENDPGNNFYVIDYGTFTASNKSKSIYEVYKGEGFFGELALLYNCPRSASVIADTDGGLWVIDRVTFRQLILKSAYQKRQRYLKFISSVPLLEDLTKYEQCNLADALKTKTINNEKVISQGDAGDKMYFIEEGEVLVTVRTGEEEREESRLKAGDYFGEVALLANIPRIANVYALGYTKLAELDAKSYTRLLGPCIDNMRKNFTKYRSQLEKLLSRHQLEELFPELIN 390
BLAST of cAMP-dependent protein kinase type II regulatory subunit vs. Planmine SMEST
Match: SMESG000017499.1 (SMESG000017499.1) HSP 1 Score: 256.914 bits (655), Expect = 7.819e-82 Identity = 159/383 (41.51%), Postives = 231/383 (60.31%), Query Frame = 1
Query: 97 LTEVIEEFKKQVEIANPKDIIAYAATYFTKKVAQENESNDTEFDKSLDYDSSSEDGDSLKEIMSNDKSKMKLVQTSNVPRQSITCESFDPSSIDDETFEKNRKIYPKTPKQMDKITDILETIFFFNCLDEIQFSKIIQSMFFIEVFKGDEIIKENDPGNNFYVIDYGTFTASNKSKSIYEVYKGEGFFGELALLYNCPRSASVIADTDGGLWVIDRVTFRQLILKSAYQKRQRYLKFISSVPLLEDLTKYEQCNLADALKTKTI-NNEKVISQGDAGDKMYFIXXXXXXXXXXXXXXX--XXXSRLKAGDYFGEVALLANIPRIANVYALGYTKLAELDAKSYTRLLGPCIDNMRKNFTKYRSQLEKLLSRHQLEELFPELIN 1236
LTE+++ F V P +++ YA YF ++ E N++ + SED D ND + K VQ RQS+ ESFDP DDE IY KT Q ++ + ++ IF F LD+ Q K+I SM + V ++I + D G++FYVI+ G F I Y G FGELAL+YN PR+A++I+ T+G LW +DR TFR ++LK+A++KRQ Y + SV LL++L+ Y++ N+ADAL ++T ++E ++ QG G +M+FIE GEV V T + +E +RL GDYFGEVALL PR+A+VYA+G T +A LD KS+ RLLGPCI+ M+KN KYR+QL ++L +++E+ PEL +
Sbjct: 12 LTELLQNFAISVLRHKPHNLVHYAFEYFKDLSSKHEEINNS------GNHTHSEDSD-------NDDNIKKQVQRGR--RQSVAAESFDPEKEDDEDLPV---IYSKTDAQRSRLVEAIKPIFLFRSLDDEQRGKVIDSMREVVVESDQKVIVQGDGGDDFYVIEKGMFDIFVNGSKIGN-YSDTGSFGELALMYNTPRAATIISVTNGILWAMDRKTFRHIVLKNAFKKRQMYEGLLQSVDLLDELSSYDRTNVADALVSRTYEDSEMILEQGKPGMEMFFIENGEVRVIRDTNDGSPPKEVNRLHKGDYFGEVALLIKEPRLASVYAVGKTTVAVLDIKSFERLLGPCINLMKKNLPKYRNQLREILGS-KVDEMVPELAH 374
BLAST of cAMP-dependent protein kinase type II regulatory subunit vs. Planmine SMEST
Match: SMESG000019065.1 (SMESG000019065.1) HSP 1 Score: 249.595 bits (636), Expect = 5.830e-79 Identity = 147/379 (38.79%), Postives = 222/379 (58.58%), Query Frame = 1
Query: 103 EVIEEFKKQVEIANPKDIIAYAATYFTKKVAQENESNDTEFDKSLDYDSSSEDGDSLKEIMSNDKSKMKLVQTSNVPRQSITCESFDPSSIDDETFEKNRKIYPKTPKQMDKITDILETIFFFNCLDEIQFSKIIQSMFFIEVFKGDEIIKENDPGNNFYVIDYGTF---TASNKSKSIYEVYKGEGFFGELALLYNCPRSASVIADTDGGLWVIDRVTFRQLILKSAYQKRQRYLKFISSVPLLEDLTKYEQCNLADALKTKTIN-NEKVISQGDAGDKMYFIXX--XXXXXXXXXXXXXXXXSRLKAGDYFGEVALLANIPRIANVYALGYTKLAELDAKSYTRLLGPCIDNMRKNFTKYRSQLEKLL-SRHQLEEL 1218
E++++F V NP+DII + YF K +++ +S DS SE+ D ++E+ + + + R+ + ESFDP DD E R +YPKTP+Q ++ ++ I F CLDE Q +I +MF V +G+++I + + G+NFYVI+ GT+ N + Y G G FGELAL+YN PR+A++ DG +W + R TFR ++LK A+QKR +Y + +VPLL++L+ YE+ N+ADAL T+ N +I QG+ G +MYF+EE V V + E E +R+ G YFGE+ALL PR A+VY + TKLA LD S+ RLLGPC+D M+++ + Y QL+ + S H++ EL
Sbjct: 14 ELLQDFTVCVLRDNPEDIIQFGIDYFKTKKSEQLQSAH--------LDSESENDDQMEELPPMPRPQGR--------RRGVAAESFDPEKEDDPNQE--RIVYPKTPEQRARLNMAVQNILLFRCLDEEQMVDVIDAMFERRVVQGEKVIIQGEDGDNFYVIESGTYDIIVKINGVDTKVGKYDGSGSFGELALMYNTPRAATIQTVNDGVVWAMTRETFRSIVLKKAFQKRLKYEALLENVPLLKELSPYERMNIADALLTRIYEPNTTIIKQGEPGLEMYFLEEGCVRVTVREAGSDTEAEVTRIGPGGYFGELALLTKHPRAASVYCVEKTKLAILDVGSFERLLGPCLDIMQRSISNYEEQLKGIFGSLHKMPEL 374
BLAST of cAMP-dependent protein kinase type II regulatory subunit vs. Planmine SMEST
Match: SMESG000023850.1 (SMESG000023850.1) HSP 1 Score: 223.016 bits (567), Expect = 1.595e-68 Identity = 137/358 (38.27%), Postives = 208/358 (58.10%), Query Frame = 1
Query: 145 PKDIIAYAATYFTKKVAQENESNDTEFDKSLDYDSSSEDGDSLKEIM-SNDKSKMKLVQTSNVPRQSITCESFDPSSIDDETFEKNRKIYPKTPKQMDKITDILETIFFFNCLDEIQFSKIIQSMFFIEVFKGDEIIKENDPGNNFYVIDYGTFTA----SNKSKSIYEVYKGEGFFGELALLYNCPRSASVIADTDGGLWVIDRVTFRQLILKSAYQKRQRYLKFISSVPLLEDLTKYEQCNLADALKTKTINN-EKVISQGDAGDKMYFIXXXXXXXXXXXXXXXXXXSRLKAGDYFGEVALLANIPRIANVYALGYTKLAELDAKSYTRLLGPCIDNMRKNFTKYRSQLEKLLSR 1200
P D + Y + YF K +E + KS D S +SL + + S D +++ +N R+S+ E D + + + PKT +Q ++ ++ + I F LD+ Q + +I +MF +E G+ II + D G+NFYVID G F +K K I+ VY+ EGFFGELAL+YN RSA+V A+T G LW +DR TFR L++ + ++Q Y F+ P+ +++T E+ N+ADAL K ++ E +I QG G +M+FIE GEVL+T +E E +RL G YFGE+ALL+N R A+ A+G T+ A LD K++ RL+GPC++ M++N Y +QLE L +
Sbjct: 28 PDDFVEYVSNYFLKIY---DEQGHNKVYKSPHNDQSDSFVNSLLDSLDSIDSEDIEVKPKANYRRKSVAAER--IDMDDIDDDDDIYAVIPKTDEQRQRLKEVCKQILLFQALDDDQLNHVINAMFLVEPKPGENIIVQGDDGDNFYVIDSGIFNCYIKDGDKDKLIH-VYENEGFFGELALMYNAVRSATVTAETAGTLWAMDRKTFRSLVVVQTHNRKQIYDTFLKQFPIFQEMTASERMNIADALVPKKYDDKEVIIKQGRPGQEMFFIENGEVLITKVHQGKEIEITRLHVGQYFGELALLSNQARQASAQAVGETRCAMLDVKTFERLMGPCLEIMKRNIEDYNTQLENLFGK 379
BLAST of cAMP-dependent protein kinase type II regulatory subunit vs. Planmine SMEST
Match: SMESG000057377.1 (SMESG000057377.1) HSP 1 Score: 222.246 bits (565), Expect = 2.216e-68 Identity = 139/369 (37.67%), Postives = 208/369 (56.37%), Query Frame = 1
Query: 106 VIEEFKKQVEIANPKDIIAYAATYFTKKVAQENESNDTEFDKSLDYDSSSEDGDSLKEIMSNDK-SKMKLVQTSNVPRQSITCESFDPSSIDDETFEKNRKIYPKTPKQMDKITDILETIFFFNCLDEIQFSKIIQSMFFIEVFKGDEIIKENDPGNNFYVID---YGTFTASNKSKSIYEVYKGEGFFGELALLYNCPRSASVIADTDGGLWVIDRVTFRQLILKSAYQKRQRYLKFISSVPLLEDLTKYEQCNLADALKTK-TINNEKVISQGDAGDKMYFIXXXXXXXXXXXXXXXXXXSRLKAGDYFGEVALLANIPRIANVYALGYTKLAELDAKSYTRLLGPCIDNMRKNFTKYRSQLEKLLS 1197
++ +F V P + I +A+ YFT+ Q N+S LD +SS SL E ND + Q +N R+S+ E F+P ++ + + +++ K+ +Q ++ + E + F L + II +M+ I+V G EII E D G+NFY+I+ Y F N K + Y EG FGELAL+YN R+AS+IA T G +W + R FR ++L A+++R+ Y K + VP+L L+ +E+ N+ADAL K I+ E +I +GD G MYFI G+V + T EE+ + L G YFGE+ALL+N PR ANV AL T LA LD KS+ RL+GPCI+ M++N Y+ + L +
Sbjct: 14 ILHQFTYAVMERKPTNYIHFASKYFTR--LQNNQS--------LDRITSSFGSVSLSEASDNDSVDTLDSKQYAN-RRKSVAAERFNPEDLN--SLDIQMEVHEKSEEQRSRLRKVCEKVSIFKSLSNADVTSIIDAMYEIKVKPGQEIIVEGDSGDNFYIIESGIYDAFITVNGEKKKIKTYDNEGNFGELALMYNALRAASIIASTSGIIWAVTRQVFRSVVLVKAHRQREMYNKLLEQVPMLAPLSDFERANIADALTPKECISKELIIVEGDPGYHMYFIISGKVEIYRTTVEEKVVINELGPGKYFGELALLSNQPRAANVKALEDTVLAVLDVKSFERLMGPCIEVMKRNMDDYKKNVVDLFN 369 The following BLAST results are available for this feature:
BLAST of cAMP-dependent protein kinase type II regulatory subunit vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of cAMP-dependent protein kinase type II regulatory subunit vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of cAMP-dependent protein kinase type II regulatory subunit vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of cAMP-dependent protein kinase type II regulatory subunit vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of cAMP-dependent protein kinase type II regulatory subunit vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of cAMP-dependent protein kinase type II regulatory subunit vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of cAMP-dependent protein kinase type II regulatory subunit vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of cAMP-dependent protein kinase type II regulatory subunit vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of cAMP-dependent protein kinase type II regulatory subunit vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of cAMP-dependent protein kinase type II regulatory subunit vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of cAMP-dependent protein kinase type II regulatory subunit vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 1
BLAST of cAMP-dependent protein kinase type II regulatory subunit vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of cAMP-dependent protein kinase type II regulatory subunit vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of cAMP-dependent protein kinase type II regulatory subunit vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30008798 ID=SMED30008798|Name=cAMP-dependent protein kinase type II regulatory subunit|organism=Schmidtea mediterranea sexual|type=transcript|length=1311bpback to top protein sequence of SMED30008798-orf-1 >SMED30008798-orf-1 ID=SMED30008798-orf-1|Name=SMED30008798-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=391bp MNNQNYSKKILTEVIEEFKKQVEIANPKDIIAYAATYFTKKVAQENESNDback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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