innexin-1
Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30008787 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 12
Homology
BLAST of innexin-1 vs. Ensembl Human
Match: PANX2 (pannexin 2 [Source:HGNC Symbol;Acc:HGNC:8600]) HSP 1 Score: 58.5362 bits (140), Expect = 2.489e-8 Identity = 45/158 (28.48%), Postives = 67/158 (42.41%), Query Frame = 2 Query: 488 FDRCVYILTFTLLLVCSATVTIKSYVLEPMTCYAPSTISGSNVLPYINNYCW--IVGTIPKAVHEHNTDDEEYWKWLESRKINYYQWVPFVLGLQAALLYIPYVFWECLIYNRLGTNLQFLIDLARKASLDFGESRQRKISQMAGSIFILLTTRKKKS 955 FDR V I T + ++ V K++ EP+ CY P + L Y YCW + +P D W L K ++P+ L AA++Y+P + WE L RL + L FL+ E R KI + S +T R+K+ Sbjct: 50 FDRVVTIGTVLVPILLVTLVFTKNFAEEPIYCYTPHNFTRDQAL-YARGYCWTELRDALPGV-------DASLWPSLFEHK-----FLPYALLAFAAIMYVPALGWEFLASTRLTSELNFLLQEIDNCYHRAAEGRAPKIEKQIQSKGPGITEREKRE 194
BLAST of innexin-1 vs. Ensembl Human
Match: PANX2 (pannexin 2 [Source:HGNC Symbol;Acc:HGNC:8600]) HSP 1 Score: 58.5362 bits (140), Expect = 2.535e-8 Identity = 45/158 (28.48%), Postives = 67/158 (42.41%), Query Frame = 2 Query: 488 FDRCVYILTFTLLLVCSATVTIKSYVLEPMTCYAPSTISGSNVLPYINNYCW--IVGTIPKAVHEHNTDDEEYWKWLESRKINYYQWVPFVLGLQAALLYIPYVFWECLIYNRLGTNLQFLIDLARKASLDFGESRQRKISQMAGSIFILLTTRKKKS 955 FDR V I T + ++ V K++ EP+ CY P + L Y YCW + +P D W L K ++P+ L AA++Y+P + WE L RL + L FL+ E R KI + S +T R+K+ Sbjct: 50 FDRVVTIGTVLVPILLVTLVFTKNFAEEPIYCYTPHNFTRDQAL-YARGYCWTELRDALPGV-------DASLWPSLFEHK-----FLPYALLAFAAIMYVPALGWEFLASTRLTSELNFLLQEIDNCYHRAAEGRAPKIEKQIQSKGPGITEREKRE 194
BLAST of innexin-1 vs. Ensembl Celegans
Match: unc-9 (Innexin unc-9 [Source:UniProtKB/Swiss-Prot;Acc:O01393]) HSP 1 Score: 186.037 bits (471), Expect = 1.042e-52 Identity = 116/376 (30.85%), Postives = 190/376 (50.53%), Query Frame = 2 Query: 482 DIFDRCVYILTFTLLLVCSATVTIKSYVLEPMTCYAPSTISGSNVLPYINNYCWIVGTIPKAVHE---HNTDDEEYWKWLESRKINYYQWVPFVLGLQAALLYIPYVFWECLIYNRLGTNLQFLIDLARKASLDFGESRQRKISQMAGSIFILLTTRKKKSE----KAIGLLSKFPIYKMEIVFHYLLLKVISIVMICSQFVIMEKLLNMNGKHKLFGITVLQDLLNGRYWDVTNLFPRMAFCRVPFKMQNTNVVNITTQCSLSINLINEKIFIFLWWWFSLIASLQIISLFIWIARCLSSDRRVRFINHSAQISRSFPSHNEHLIKQFERNLISIDGIFLIHMTRINCGDLICNELIHKLYEIHATSLANRGDDL 1588 DI D+ Y T ++ V + V+ K YV P+ C+ P+T + + Y NYCW+ T +H+ HN + E +R+I YYQWVPFVL L+A L Y+P + W L + G ++Q L+ +A + L ESR R + +A ++ L + + K + L+ + F Y+ +K++ V I Q ++ L + K +G+ VL DL+NGR W+ + FPR+ C K+ NV T QC L IN+ NEKIF+FLW+W+ L+A + SLF WI + R++ F+ + + +++F + + DG+FL+ M + G+L C EL L+ + + + D+ Sbjct: 22 DIIDKLNYYYTTAIITVFAILVSAKQYVGFPIQCWVPATFT-EPMEQYTENYCWVQNTYFLPLHDYIPHNYAERE------NRQIGYYQWVPFVLALEALLFYVPTIVWRLLSWQS-GIHVQSLVQMACDSRLLDLESRNRALQTIATNVEEALHVKHQVMSGNRLKLLNLIICTRSSGAAVTFLYISVKILYTVNIVGQIFLLNTFLG--NRSKWYGLQVLNDLMNGREWEESGHFPRVTLCDFEVKVLG-NVHRHTVQCVLMINMFNEKIFLFLWFWYFLLAGATLCSLFYWIYISVVPSRQLNFVGKYLTGIEGYKMVDSQSLRRFVFHFLRQDGVFLLRMVATHAGELPCYELAKTLWNNYCDNKEGKMHDV 386
BLAST of innexin-1 vs. Ensembl Celegans
Match: inx-13 (Innexin [Source:UniProtKB/TrEMBL;Acc:O44887]) HSP 1 Score: 174.481 bits (441), Expect = 1.874e-48 Identity = 108/375 (28.80%), Postives = 187/375 (49.87%), Query Frame = 2 Query: 461 IHACGVYDIFDRCVYILTFTLLLVCSATVTIKSYVLEPMTCYAPSTISGSNVLPYINNYCWIVGTIPKAVHEHNTDDEEYWKWLESRKINYYQWVPFVLGLQAALLYIPYVFWECLIYNRLGTNLQFLIDLARKASLDFGESRQRKISQMAGSIFILLTTRKKKSEKAIGLLSKFPIYKMEIVFHYLLLKVISIVMICSQFVIMEKLLNMNGKHKLFGITVLQDLLNGRYWDVTNLFPRMAFCRVPFKMQNTNVVNITTQCSLSINLINEKIFIFLWWWFSLIASLQIISLFIWIARCLSSDRRVRFINHSAQISRSFP---SHNEHLIKQFERNLISIDGIFLIHMTRINCGDLICNELIHKLYEIHATSLANR 1576 +H G D DR Y T LL++ + T++ K YV +P+ C+ P+ +G+ Y NYC++ T + ++ D E E +I YYQWVPF+LGLQA L Y+P +FW + +N G L+ ++ A+KA ++R ++ LT + + ++ S F + + YL +K + +V I QF+I+ L + + +G+ +L D+LNGR W+ + FPR+ C ++ N T QC L IN+ NEK+++FLW+W ++ ++L W + + R I QI +F S N ++ +F + DG+F+ H+ N G + +++I +++ NR Sbjct: 11 LHKQGDDDSIDRLNYYWTPMLLVIFALTLSAKQYVGQPIQCWIPAQFTGA-WEQYSENYCFVQNTYFISPDKYIPDSEID---REGAEIGYYQWVPFILGLQAILFYLPSLFWRLMNFNS-GVALKKMLFGAKKADRVDEKARNEAAKSTGAHLYESLTLQSRFAKYT----SAFTYGGSYLTYLYLFVKFLYLVQIVFQFIILNNFLGTS--YTFWGLGILSDILNGREWEESGHFPRVTMCDFEVRVLG-NKHRHTVQCVLMINMFNEKVYVFLWFWLVIVGVATFLNLVNWTRKLMFRSARKAHIKSYLQIEDNFSDDNSRNGQILDKFVDYKLKSDGVFITHLIDNNGGSVFSHDVIVDMWDRFLQDEDNR 373
BLAST of innexin-1 vs. Ensembl Celegans
Match: inx-1 (Innexin [Source:UniProtKB/TrEMBL;Acc:Q17394]) HSP 1 Score: 167.933 bits (424), Expect = 4.080e-46 Identity = 105/361 (29.09%), Postives = 182/361 (50.42%), Query Frame = 2 Query: 482 DIFDRCVYILTFTLLLVCSATVTIKSYVLEPMTCYAPSTISGSNVLPYINNYCWIVGT----IPKAVHEHNTDDEEYWKWLESRKINYYQWVPFVLGLQAALLYIPYVFWECLIYNRLGTNLQFLIDLARKASLDFGESRQRKISQMAGSIFILLTTRKKKSEKAIGLLSKFPIYKMEIVFHYLLLKVISIVMICSQFVIMEKLLNMNGKHKLF-GITVLQDLLNGRYWDVTNLFPRMAFCRVPFKMQNTNVVNITTQCSLSINLINEKIFIFLWWWFSLIASLQIISLFIWIARCLSSDRRVRFINHSAQISRSFPSHNEHLIKQFERNLISIDGIFLIHMTRINCGDLICNELIHKLYE 1549 D D+ Y T ++ + V+ K YV P+ C+ P+ + + Y NYCW+ T + A D +R+I+YYQWVPFVL L+A YIP + W L++ G N+Q L +A A + ++R + +AG + L +++ ++ + + K + + Y+ +K++ + + Q ++ L G LF G +L+DLLNGR W+V+ FPR+ C ++ NV + T QC L IN+ NEKIF+FLW+W+ ++A + +S+F WI + ++FI + + + + +K+F + DG+F + M + GD++ ELI L+ Sbjct: 20 DFVDKLNYHYTSAIIFAFAIIVSAKQYVGYPIQCWVPAQFTDA-WEQYTENYCWVENTYYLPLTSAFPLEYGDRR-------ARQISYYQWVPFVLALEALCFYIPCIMWRGLLHWHSGINVQSLTQMACDARMMDADARAATVQTIAGHMEDALEIQREVTDVSGMCVQK--RWANYVTLLYVFIKMLYLGNVVLQVFMLNSFL---GTDNLFYGFHILRDLLNGREWEVSGNFPRVTMCDFEVRVLG-NVHHHTVQCVLMINMFNEKIFLFLWFWYFMVAFVSAVSMFHWIIISFLPGQHMKFIRKYLRATDL--ATDRQSVKKFVHKFLGYDGVFCMRMISAHAGDILATELIVALWH 364
BLAST of innexin-1 vs. Ensembl Celegans
Match: inx-1 (Innexin [Source:UniProtKB/TrEMBL;Acc:Q17394]) HSP 1 Score: 167.933 bits (424), Expect = 4.080e-46 Identity = 105/361 (29.09%), Postives = 182/361 (50.42%), Query Frame = 2 Query: 482 DIFDRCVYILTFTLLLVCSATVTIKSYVLEPMTCYAPSTISGSNVLPYINNYCWIVGT----IPKAVHEHNTDDEEYWKWLESRKINYYQWVPFVLGLQAALLYIPYVFWECLIYNRLGTNLQFLIDLARKASLDFGESRQRKISQMAGSIFILLTTRKKKSEKAIGLLSKFPIYKMEIVFHYLLLKVISIVMICSQFVIMEKLLNMNGKHKLF-GITVLQDLLNGRYWDVTNLFPRMAFCRVPFKMQNTNVVNITTQCSLSINLINEKIFIFLWWWFSLIASLQIISLFIWIARCLSSDRRVRFINHSAQISRSFPSHNEHLIKQFERNLISIDGIFLIHMTRINCGDLICNELIHKLYE 1549 D D+ Y T ++ + V+ K YV P+ C+ P+ + + Y NYCW+ T + A D +R+I+YYQWVPFVL L+A YIP + W L++ G N+Q L +A A + ++R + +AG + L +++ ++ + + K + + Y+ +K++ + + Q ++ L G LF G +L+DLLNGR W+V+ FPR+ C ++ NV + T QC L IN+ NEKIF+FLW+W+ ++A + +S+F WI + ++FI + + + + +K+F + DG+F + M + GD++ ELI L+ Sbjct: 20 DFVDKLNYHYTSAIIFAFAIIVSAKQYVGYPIQCWVPAQFTDA-WEQYTENYCWVENTYYLPLTSAFPLEYGDRR-------ARQISYYQWVPFVLALEALCFYIPCIMWRGLLHWHSGINVQSLTQMACDARMMDADARAATVQTIAGHMEDALEIQREVTDVSGMCVQK--RWANYVTLLYVFIKMLYLGNVVLQVFMLNSFL---GTDNLFYGFHILRDLLNGREWEVSGNFPRVTMCDFEVRVLG-NVHHHTVQCVLMINMFNEKIFLFLWFWYFMVAFVSAVSMFHWIIISFLPGQHMKFIRKYLRATDL--ATDRQSVKKFVHKFLGYDGVFCMRMISAHAGDILATELIVALWH 364
BLAST of innexin-1 vs. Ensembl Celegans
Match: unc-9 (Innexin unc-9 [Source:UniProtKB/Swiss-Prot;Acc:O01393]) HSP 1 Score: 165.236 bits (417), Expect = 9.685e-46 Identity = 102/329 (31.00%), Postives = 166/329 (50.46%), Query Frame = 2 Query: 623 YINNYCWIVGTIPKAVHE---HNTDDEEYWKWLESRKINYYQWVPFVLGLQAALLYIPYVFWECLIYNRLGTNLQFLIDLARKASLDFGESRQRKISQMAGSIFILLTTRKK----KSEKAIGLLSKFPIYKMEIVFHYLLLKVISIVMICSQFVIMEKLLNMNGKHKLFGITVLQDLLNGRYWDVTNLFPRMAFCRVPFKMQNTNVVNITTQCSLSINLINEKIFIFLWWWFSLIASLQIISLFIWIARCLSSDRRVRFINHSAQISRSFPSHNEHLIKQFERNLISIDGIFLIHMTRINCGDLICNELIHKLYEIHATSLANRGDDL 1588 Y NYCW+ T +H+ HN + E +R+I YYQWVPFVL L+A L Y+P + W L + G ++Q L+ +A + L ESR R + +A ++ L + + K + L+ + F Y+ +K++ V I Q ++ L + K +G+ VL DL+NGR W+ + FPR+ C K+ NV T QC L IN+ NEKIF+FLW+W+ L+A + SLF WI + R++ F+ + + +++F + + DG+FL+ M + G+L C EL L+ + + + D+ Sbjct: 4 YTENYCWVQNTYFLPLHDYIPHNYAERE------NRQIGYYQWVPFVLALEALLFYVPTIVWRLLSWQS-GIHVQSLVQMACDSRLLDLESRNRALQTIATNVEEALHVKHQVMSGNRLKLLNLIICTRSSGAAVTFLYISVKILYTVNIVGQIFLLNTFLG--NRSKWYGLQVLNDLMNGREWEESGHFPRVTLCDFEVKVLG-NVHRHTVQCVLMINMFNEKIFLFLWFWYFLLAGATLCSLFYWIYISVVPSRQLNFVGKYLTGIEGYKMVDSQSLRRFVFHFLRQDGVFLLRMVATHAGELPCYELAKTLWNNYCDNKEGKMHDV 322
BLAST of innexin-1 vs. Ensembl Fly
Match: Inx3 (gene:FBgn0265274 transcript:FBtr0085350) HSP 1 Score: 87.4261 bits (215), Expect = 4.050e-18 Identity = 84/369 (22.76%), Postives = 148/369 (40.11%), Query Frame = 2 Query: 494 RCVYILTFTLLLVCSATVTIKSYVLEPMTCYAPSTISGSNVLPYINNYCWIVGT--IPKAVHEHNTDD-------EEYWKWLESRKINYYQWVPFVLGLQAALLYIPYVFWECLIYNRLGTNLQFLIDLARKASLDFGESRQRKISQMAGSIFILLTTRKKKSEKAIGLLSKFPIYKMEI----VFHYLLLKVISIVMICSQFVIMEKLLNMNGKHKLFGITVL------QDLLNGRYWDVTNLFPRMAFCRVPFKMQNTNVVNITTQCSLSINLINEKIFIFLWWWFSLIASLQIISLFIWIARCLSSDRRVRFINHSAQISRSFPSHNEHLIKQFERNLISIDGIFLIHMTRINCGDLICNELIHKL 1543 RC Y +T +L C VT + + +P++C I + IN +CWI T IP H D EY + E R +YYQWVPFVL Q + Y+P+ W+ + KI + + +++ + K+ + + F Y ++++ + + +++K L G +G VL QD R+ + +FPR+ C + +V T C L++N++NEKI+IFLW+WF ++A++ +++ + + R I RS+ S I R L I ++H N ++++ +L Sbjct: 31 RCHYRITTAILFTCCIIVTANNLIGDPISCINDGAIP----MHVINTFCWITYTYTIPGQQHRQIGTDVAGPGLGNEYGQ--EKRYHSYYQWVPFVLFFQGLMFYVPHWVWKNM--------------------------EDGKIRMITDGLRGMVSVPDDYRRDRQDRILKYFVNSLNTHNGYSFAYFFCELLNFINVIVNIFMVDKFL--GGAFMSYGTDVLKFSNMDQD---KRFDPMIEIFPRLTKCTFHKFGPSGSVQKHDTLCVLALNILNEKIYIFLWFWFIILATISGVAVLYSLVVIMMPTTR------ETIIKRSYRSAQRKEIAGLVRRL-EIGDFLILHFLSQNLSTRSYSDMLQQL 355
BLAST of innexin-1 vs. Ensembl Fly
Match: Inx3 (gene:FBgn0265274 transcript:FBtr0330306) HSP 1 Score: 87.4261 bits (215), Expect = 4.050e-18 Identity = 84/369 (22.76%), Postives = 148/369 (40.11%), Query Frame = 2 Query: 494 RCVYILTFTLLLVCSATVTIKSYVLEPMTCYAPSTISGSNVLPYINNYCWIVGT--IPKAVHEHNTDD-------EEYWKWLESRKINYYQWVPFVLGLQAALLYIPYVFWECLIYNRLGTNLQFLIDLARKASLDFGESRQRKISQMAGSIFILLTTRKKKSEKAIGLLSKFPIYKMEI----VFHYLLLKVISIVMICSQFVIMEKLLNMNGKHKLFGITVL------QDLLNGRYWDVTNLFPRMAFCRVPFKMQNTNVVNITTQCSLSINLINEKIFIFLWWWFSLIASLQIISLFIWIARCLSSDRRVRFINHSAQISRSFPSHNEHLIKQFERNLISIDGIFLIHMTRINCGDLICNELIHKL 1543 RC Y +T +L C VT + + +P++C I + IN +CWI T IP H D EY + E R +YYQWVPFVL Q + Y+P+ W+ + KI + + +++ + K+ + + F Y ++++ + + +++K L G +G VL QD R+ + +FPR+ C + +V T C L++N++NEKI+IFLW+WF ++A++ +++ + + R I RS+ S I R L I ++H N ++++ +L Sbjct: 31 RCHYRITTAILFTCCIIVTANNLIGDPISCINDGAIP----MHVINTFCWITYTYTIPGQQHRQIGTDVAGPGLGNEYGQ--EKRYHSYYQWVPFVLFFQGLMFYVPHWVWKNM--------------------------EDGKIRMITDGLRGMVSVPDDYRRDRQDRILKYFVNSLNTHNGYSFAYFFCELLNFINVIVNIFMVDKFL--GGAFMSYGTDVLKFSNMDQD---KRFDPMIEIFPRLTKCTFHKFGPSGSVQKHDTLCVLALNILNEKIYIFLWFWFIILATISGVAVLYSLVVIMMPTTR------ETIIKRSYRSAQRKEIAGLVRRL-EIGDFLILHFLSQNLSTRSYSDMLQQL 355
BLAST of innexin-1 vs. Ensembl Fly
Match: Inx3 (gene:FBgn0265274 transcript:FBtr0345207) HSP 1 Score: 87.4261 bits (215), Expect = 4.050e-18 Identity = 84/369 (22.76%), Postives = 148/369 (40.11%), Query Frame = 2 Query: 494 RCVYILTFTLLLVCSATVTIKSYVLEPMTCYAPSTISGSNVLPYINNYCWIVGT--IPKAVHEHNTDD-------EEYWKWLESRKINYYQWVPFVLGLQAALLYIPYVFWECLIYNRLGTNLQFLIDLARKASLDFGESRQRKISQMAGSIFILLTTRKKKSEKAIGLLSKFPIYKMEI----VFHYLLLKVISIVMICSQFVIMEKLLNMNGKHKLFGITVL------QDLLNGRYWDVTNLFPRMAFCRVPFKMQNTNVVNITTQCSLSINLINEKIFIFLWWWFSLIASLQIISLFIWIARCLSSDRRVRFINHSAQISRSFPSHNEHLIKQFERNLISIDGIFLIHMTRINCGDLICNELIHKL 1543 RC Y +T +L C VT + + +P++C I + IN +CWI T IP H D EY + E R +YYQWVPFVL Q + Y+P+ W+ + KI + + +++ + K+ + + F Y ++++ + + +++K L G +G VL QD R+ + +FPR+ C + +V T C L++N++NEKI+IFLW+WF ++A++ +++ + + R I RS+ S I R L I ++H N ++++ +L Sbjct: 31 RCHYRITTAILFTCCIIVTANNLIGDPISCINDGAIP----MHVINTFCWITYTYTIPGQQHRQIGTDVAGPGLGNEYGQ--EKRYHSYYQWVPFVLFFQGLMFYVPHWVWKNM--------------------------EDGKIRMITDGLRGMVSVPDDYRRDRQDRILKYFVNSLNTHNGYSFAYFFCELLNFINVIVNIFMVDKFL--GGAFMSYGTDVLKFSNMDQD---KRFDPMIEIFPRLTKCTFHKFGPSGSVQKHDTLCVLALNILNEKIYIFLWFWFIILATISGVAVLYSLVVIMMPTTR------ETIIKRSYRSAQRKEIAGLVRRL-EIGDFLILHFLSQNLSTRSYSDMLQQL 355
BLAST of innexin-1 vs. Ensembl Fly
Match: Inx2 (gene:FBgn0027108 transcript:FBtr0301860) HSP 1 Score: 80.8777 bits (198), Expect = 5.012e-16 Identity = 92/370 (24.86%), Postives = 153/370 (41.35%), Query Frame = 2 Query: 494 RCVYILTFTLLLVCSATVTIKSYVLEPMTCYAPSTISGSNVLPYINNYCWIVGT--IPK---------------AVHEHNTDDEEYWKWLESRKINYYQWVPFVLGLQAALLYIPYVFWECLIYNRLGTNLQFLIDLARKASLDFGESRQRKISQMAGSIFILLTTRKKKSEKAIGLLSKFPIYKMEIVFHYLLLKVISIVMICSQFVIMEKLLNMNGKHKLFGITVLQDL---LNGRYWDVTNLFPRMAFCRVPFKMQNTNVVNITTQCSLSINLINEKIFIFLWWWFSLIASLQIISLFIWIARCLSSDRRVRFINHSAQISRSFPSHNEHLIKQFERNLISIDGIFLIHMTRINCGDLICNELIHKL 1543 R Y T +L+ S VT + Y+ +P+ C I L ++ YCWI T +P+ H D+ +Y K YYQWV FVL QA L Y+P W+ RL ++DL D ++ ++KI + IG L++ Y F + + + ++ V + Q ++ L+ G+ +G VL+ + R + +FP++ C + +V C L +N++NEKI++FLW+WF +++ + ISL IA R H +RS + +E + + N +I FL++ N LI E+I L Sbjct: 25 RMHYKATVIILIAFSLLVTSRQYIGDPIDC-----IVDEIPLGVMDTYCWIYSTFTVPERLTGITGRDVVQPGVGSHVEGEDEVKYHK--------YYQWVCFVLFFQAILFYVPRYLWKSWEGGRLK---MLVMDLNSPIVNDECKNDRKKIL----------------VDYFIGNLNRHNFY----AFRFFVCEALNFVNVIGQIYFVDFFLD--GEFSTYGSDVLKFTELEPDERIDPMARVFPKVTKCTFHKYGPSGSVQTHDGLCVLPLNIVNEKIYVFLWFWFIILSIMSGISLIYRIAVVAGPKLR-----HLLLRARSRLAESEEV--ELVANKCNIGDWFLLYQLGKNIDPLIYKEVISDL 349
BLAST of innexin-1 vs. Ensembl Fly
Match: Inx2 (gene:FBgn0027108 transcript:FBtr0071005) HSP 1 Score: 80.8777 bits (198), Expect = 5.012e-16 Identity = 92/370 (24.86%), Postives = 153/370 (41.35%), Query Frame = 2 Query: 494 RCVYILTFTLLLVCSATVTIKSYVLEPMTCYAPSTISGSNVLPYINNYCWIVGT--IPK---------------AVHEHNTDDEEYWKWLESRKINYYQWVPFVLGLQAALLYIPYVFWECLIYNRLGTNLQFLIDLARKASLDFGESRQRKISQMAGSIFILLTTRKKKSEKAIGLLSKFPIYKMEIVFHYLLLKVISIVMICSQFVIMEKLLNMNGKHKLFGITVLQDL---LNGRYWDVTNLFPRMAFCRVPFKMQNTNVVNITTQCSLSINLINEKIFIFLWWWFSLIASLQIISLFIWIARCLSSDRRVRFINHSAQISRSFPSHNEHLIKQFERNLISIDGIFLIHMTRINCGDLICNELIHKL 1543 R Y T +L+ S VT + Y+ +P+ C I L ++ YCWI T +P+ H D+ +Y K YYQWV FVL QA L Y+P W+ RL ++DL D ++ ++KI + IG L++ Y F + + + ++ V + Q ++ L+ G+ +G VL+ + R + +FP++ C + +V C L +N++NEKI++FLW+WF +++ + ISL IA R H +RS + +E + + N +I FL++ N LI E+I L Sbjct: 25 RMHYKATVIILIAFSLLVTSRQYIGDPIDC-----IVDEIPLGVMDTYCWIYSTFTVPERLTGITGRDVVQPGVGSHVEGEDEVKYHK--------YYQWVCFVLFFQAILFYVPRYLWKSWEGGRLK---MLVMDLNSPIVNDECKNDRKKIL----------------VDYFIGNLNRHNFY----AFRFFVCEALNFVNVIGQIYFVDFFLD--GEFSTYGSDVLKFTELEPDERIDPMARVFPKVTKCTFHKYGPSGSVQTHDGLCVLPLNIVNEKIYVFLWFWFIILSIMSGISLIYRIAVVAGPKLR-----HLLLRARSRLAESEEV--ELVANKCNIGDWFLLYQLGKNIDPLIYKEVISDL 349
BLAST of innexin-1 vs. Ensembl Zebrafish
Match: panx2 (pannexin 2 [Source:ZFIN;Acc:ZDB-GENE-050419-55]) HSP 1 Score: 51.9878 bits (123), Expect = 1.763e-6 Identity = 40/158 (25.32%), Postives = 66/158 (41.77%), Query Frame = 2 Query: 488 FDRCVYILTFTLLLVCSATVTIKSYVLEPMTCYAPSTISGSNVLPYINNYCW--IVGTIPKAVHEHNTDDEEYWKWLESRKINYYQWVPFVLGLQAALLYIPYVFWECLIYNRLGTNLQFLIDLARKASLDFGESRQRKISQMAGSIFILLTTRKKKS 955 FDR V I T + ++ V +++ E + CY P + L Y YCW + +P D E E ++++P+ L A ++YIP + WE + RL + L FL+ E R KI + S +T R+++ Sbjct: 41 FDRVVTIGTVIIPILLVTLVFTRNFAEESIYCYTPHNFTRDQAL-YARGYCWTELRDAVP------GVDPELRPSLFE------HKFLPYALLAFAGIMYIPALGWEFMASTRLTSELNFLLQEIDNCYHRAAEGRAPKIEKQIQSKGPGITERERRE 185
BLAST of innexin-1 vs. Ensembl Zebrafish
Match: panx2 (pannexin 2 [Source:ZFIN;Acc:ZDB-GENE-050419-55]) HSP 1 Score: 51.6026 bits (122), Expect = 2.158e-6 Identity = 40/158 (25.32%), Postives = 66/158 (41.77%), Query Frame = 2 Query: 488 FDRCVYILTFTLLLVCSATVTIKSYVLEPMTCYAPSTISGSNVLPYINNYCW--IVGTIPKAVHEHNTDDEEYWKWLESRKINYYQWVPFVLGLQAALLYIPYVFWECLIYNRLGTNLQFLIDLARKASLDFGESRQRKISQMAGSIFILLTTRKKKS 955 FDR V I T + ++ V +++ E + CY P + L Y YCW + +P D E E ++++P+ L A ++YIP + WE + RL + L FL+ E R KI + S +T R+++ Sbjct: 51 FDRVVTIGTVIIPILLVTLVFTRNFAEESIYCYTPHNFTRDQAL-YARGYCWTELRDAVP------GVDPELRPSLFE------HKFLPYALLAFAGIMYIPALGWEFMASTRLTSELNFLLQEIDNCYHRAAEGRAPKIEKQIQSKGPGITERERRE 195
BLAST of innexin-1 vs. Ensembl Zebrafish
Match: panx2 (pannexin 2 [Source:ZFIN;Acc:ZDB-GENE-050419-55]) HSP 1 Score: 50.8322 bits (120), Expect = 4.342e-6 Identity = 40/157 (25.48%), Postives = 66/157 (42.04%), Query Frame = 2 Query: 488 FDRCVYILTFTLLLVCSATVTIKSYVLEPMTCYAPSTISGSNVLPYINNYCW--IVGTIPKAVHEHNTDDEEYWKWLESRKINYYQWVPFVLGLQAALLYIPYVFWECLIYNRLGTNLQFLIDLARKASLDFGESRQRKISQMAGSIFILLTTRKKK 952 FDR V I T + ++ V +++ E + CY P + L Y YCW + +P D E E ++++P+ L A ++YIP + WE + RL + L FL+ E R KI + S +T R+++ Sbjct: 51 FDRVVTIGTVIIPILLVTLVFTRNFAEESIYCYTPHNFTRDQAL-YARGYCWTELRDAVP------GVDPELRPSLFE------HKFLPYALLAFAGIMYIPALGWEFMASTRLTSELNFLLQEIDNCYHRAAEGRAPKIEKQIQSKGPGITERERR 194
BLAST of innexin-1 vs. Ensembl Xenopus
Match: alkbh1 (alkB homolog 1, histone H2A dioxygenase [Source:Xenbase;Acc:XB-GENE-6453434]) HSP 1 Score: 58.5362 bits (140), Expect = 2.375e-8 Identity = 45/157 (28.66%), Postives = 66/157 (42.04%), Query Frame = 2 Query: 488 FDRCVYILTFTLLLVCSATVTIKSYVLEPMTCYAPSTISGSNVLPYINNYCW--IVGTIPKAVHEHNTDDEEYWKWLESRKINYYQWVPFVLGLQAALLYIPYVFWECLIYNRLGTNLQFLIDLARKASLDFGESRQRKISQMAGSIFILLTTRKKK 952 FDR V I T + ++ V K++ EP+ CY P + L Y YCW + +P D W L K ++P+ L A ++YIP + WE L RL + L FL+ E R KI + S +T R+K+ Sbjct: 50 FDRVVTIGTVLIPILLVTLVFTKNFAEEPIYCYTPQNFTRDQAL-YARGYCWTELKDALPGV-------DISQWPSLFEHK-----FLPYALLAFAGIMYIPALGWEFLASTRLTSELNFLLQEIDNCYHRAAEGRAPKIEKQIQSKGPSITEREKR 193
BLAST of innexin-1 vs. Ensembl Mouse
Match: Panx2 (pannexin 2 [Source:MGI Symbol;Acc:MGI:1890615]) HSP 1 Score: 58.5362 bits (140), Expect = 2.215e-8 Identity = 45/158 (28.48%), Postives = 67/158 (42.41%), Query Frame = 2 Query: 488 FDRCVYILTFTLLLVCSATVTIKSYVLEPMTCYAPSTISGSNVLPYINNYCW--IVGTIPKAVHEHNTDDEEYWKWLESRKINYYQWVPFVLGLQAALLYIPYVFWECLIYNRLGTNLQFLIDLARKASLDFGESRQRKISQMAGSIFILLTTRKKKS 955 FDR V I T + ++ V K++ EP+ CY P + L Y YCW + +P D W L K ++P+ L AA++Y+P + WE L RL + L FL+ E R KI + S +T R+K+ Sbjct: 50 FDRVVTIGTVLVPILLVTLVFTKNFAEEPIYCYTPHNFTRDQAL-YARGYCWTELRDALPGV-------DASLWPSLFEHK-----FLPYALLAFAAIMYVPALGWEFLASTRLTSELNFLLQEIDNCYHRAAEGRAPKIEKQIQSKGPGITEREKRE 194
BLAST of innexin-1 vs. Ensembl Mouse
Match: Panx2 (pannexin 2 [Source:MGI Symbol;Acc:MGI:1890615]) HSP 1 Score: 51.6026 bits (122), Expect = 2.566e-6 Identity = 45/165 (27.27%), Postives = 67/165 (40.61%), Query Frame = 2 Query: 488 FDRCVYILTFTLLLVCSATVTIKSYVL--------EPMTCYAPSTISGSNVLPYINNYCW--IVGTIPKAVHEHNTDDEEYWKWLESRKINYYQWVPFVLGLQAALLYIPYVFWECLIYNRLGTNLQFLIDLARKASLDFGESRQRKISQMAGSIFILLTTRKKK 952 FDR V I T + ++ V K++ EP+ CY P + L Y YCW + +P D W L K ++P+ L AA++Y+P + WE L RL + L FL+ E R KI + S +T R+K+ Sbjct: 50 FDRVVTIGTVLVPILLVTLVFTKNFAARVSSLPSEEPIYCYTPHNFTRDQAL-YARGYCWTELRDALPGV-------DASLWPSLFEHK-----FLPYALLAFAAIMYVPALGWEFLASTRLTSELNFLLQEIDNCYHRAAEGRAPKIEKQIQSKGPGITEREKR 201
BLAST of innexin-1 vs. UniProt/SwissProt
Match: sp|O01393|UNC9_CAEEL (Innexin unc-9 OS=Caenorhabditis elegans OX=6239 GN=unc-9 PE=1 SV=1) HSP 1 Score: 186.037 bits (471), Expect = 1.326e-51 Identity = 116/376 (30.85%), Postives = 190/376 (50.53%), Query Frame = 2 Query: 482 DIFDRCVYILTFTLLLVCSATVTIKSYVLEPMTCYAPSTISGSNVLPYINNYCWIVGTIPKAVHE---HNTDDEEYWKWLESRKINYYQWVPFVLGLQAALLYIPYVFWECLIYNRLGTNLQFLIDLARKASLDFGESRQRKISQMAGSIFILLTTRKKKSE----KAIGLLSKFPIYKMEIVFHYLLLKVISIVMICSQFVIMEKLLNMNGKHKLFGITVLQDLLNGRYWDVTNLFPRMAFCRVPFKMQNTNVVNITTQCSLSINLINEKIFIFLWWWFSLIASLQIISLFIWIARCLSSDRRVRFINHSAQISRSFPSHNEHLIKQFERNLISIDGIFLIHMTRINCGDLICNELIHKLYEIHATSLANRGDDL 1588 DI D+ Y T ++ V + V+ K YV P+ C+ P+T + + Y NYCW+ T +H+ HN + E +R+I YYQWVPFVL L+A L Y+P + W L + G ++Q L+ +A + L ESR R + +A ++ L + + K + L+ + F Y+ +K++ V I Q ++ L + K +G+ VL DL+NGR W+ + FPR+ C K+ NV T QC L IN+ NEKIF+FLW+W+ L+A + SLF WI + R++ F+ + + +++F + + DG+FL+ M + G+L C EL L+ + + + D+ Sbjct: 22 DIIDKLNYYYTTAIITVFAILVSAKQYVGFPIQCWVPATFT-EPMEQYTENYCWVQNTYFLPLHDYIPHNYAERE------NRQIGYYQWVPFVLALEALLFYVPTIVWRLLSWQS-GIHVQSLVQMACDSRLLDLESRNRALQTIATNVEEALHVKHQVMSGNRLKLLNLIICTRSSGAAVTFLYISVKILYTVNIVGQIFLLNTFLG--NRSKWYGLQVLNDLMNGREWEESGHFPRVTLCDFEVKVLG-NVHRHTVQCVLMINMFNEKIFLFLWFWYFLLAGATLCSLFYWIYISVVPSRQLNFVGKYLTGIEGYKMVDSQSLRRFVFHFLRQDGVFLLRMVATHAGELPCYELAKTLWNNYCDNKEGKMHDV 386
BLAST of innexin-1 vs. UniProt/SwissProt
Match: sp|Q03412|UNC7_CAEEL (Innexin unc-7 OS=Caenorhabditis elegans OX=6239 GN=unc-7 PE=1 SV=1) HSP 1 Score: 161.77 bits (408), Expect = 1.063e-41 Identity = 106/367 (28.88%), Postives = 181/367 (49.32%), Query Frame = 2 Query: 482 DIFDRCVYILTFTLLLVCSATVTIKSYVLEPMTCYAPSTISGSNVLPYINNYCWIVGTIPKAVHEHNTDDEEYWKWLESRKINYYQWVPFVLGLQAALLYIPYVFWECLIYNRLGTNLQFLIDLARKASLDFGESRQRKISQMA----GSIFILLTTRKKKSEKAIGLLSKFPIYKME----IVFHYLLLKVISIVMICSQFVIMEKLLNMNGKHKLFGITVLQDLLNGRYWDVTNLFPRMAFCRVPFKMQNTNVVNITTQCSLSINLINEKIFIFLWWWFSLIASLQIISLFIWIARCLSSDRRVRFINHSAQISRSFPSH---NEHLIKQFERNLISIDGIFLIHMTRINCGDLICNELIHKLYE 1549 D D+ Y T T+L + V+ K YV P+ C+ P+T + + + Y NYCW+ T + E + E Y + +R+I YYQWVPF+L ++A L Y+P + W L+Y G NLQ L+ +A A L E + R + MA + + R+ S L + Y+ +KV+ + QF ++ LL N +G ++L+DL++ W+ T +FPR+ C ++ N+ T QC L IN+ NEKIF+FLW+WF + + + WI + + F+ ++ P+ ++ +++F N + DG+F++ M + G+L+ +ELI L++ Sbjct: 140 DFVDKLNYYYTTTILASFALLVSAKQYVGFPIQCWVPATFTDA-MEQYTENYCWVQNTYWVPMQE-DIPREIYSR--RNRQIGYYQWVPFILAIEALLFYVPCILWRGLLYWHSGINLQGLVQMACDARLMDSEIKTRTVYTMARHMQDEVQLTNIDRQGHSRSCFSNLQLGANCGRHCGCYVTMLYIGIKVLYSANVLLQFFLLNHLLGSND--LAYGFSLLKDLMHAIEWEQTGMFPRVTLCDFEVRVLG-NIHRHTVQCVLMINMFNEKIFLFLWFWFLTCGIVTVCNTMYWILIMFIPSQGMSFVRKYLRVLPDHPAKPIADDVTLRKFTNNFLRKDGVFMLRMISTHAGELMSSELILALWQ 499
BLAST of innexin-1 vs. UniProt/SwissProt
Match: sp|O61787|INX16_CAEEL (Innexin-16 OS=Caenorhabditis elegans OX=6239 GN=inx-16 PE=3 SV=2) HSP 1 Score: 154.836 bits (390), Expect = 1.959e-40 Identity = 106/363 (29.20%), Postives = 180/363 (49.59%), Query Frame = 2 Query: 491 DRCVYILTFTLLLVCSATVTIKSYVLEPMTCYAPSTISGSNVLPYINNYCWIVGTIPKAVHEHNTDDEEYWKWLESRKINYYQWVPFVLGLQAALLYIPYVFWECLIYNRL-GTNLQFLIDLARKASLDFGESRQRKISQMAGSIFILLTTRKKKSEKAIGLLSKFPIYKMEIVFHYLLLKVISIVMICSQFVIMEKLLNMNGKHKLFGITVLQDLLNGRYWDVTNLFPRMAFCRVPFKMQNTNVVNITTQCSLSINLINEKIFIFLWWWFSLIASLQIISLFIWIARCLSSDRRVRFINHSAQISRSFPSHNEHLIKQFERNLISIDGIFLIHMTRINCGDLICNELIHKLYEI---HATSL 1567 DR Y++T ++L+ S + K+YV EPM C+ P+ +G + +YC+I T + + N E E R++ YYQWVPF+L +QA +P FW +IY G + +I AR+ E + Q+A I T ++K + I YL++K++ ++ I QF ++ LN + +G + D++NGR+W + FPR++FC + + + N+ + + QC L +N+ NEKIFIFLW+WF+ + IW+ R S+ ++ FI +++ H+ + +N++ DG+ + + N G L EL+ K+Y I HAT L Sbjct: 26 DRLNYVVTTSILIAFSLLLFAKNYVGEPMQCWTPNQFAGG-WESFAESYCFIENTYFVPMQDSNLPAAET---REGREMIYYQWVPFLLVIQALFFCVPRAFW--IIYPSYSGLTIADMITAARQNGKQL-EGADEALEQVA---MINWRTEQQKGHGS------------RIFNCYLVMKLLILLNIVLQFFLLNSFLNT--AYTFWGWGIFWDMVNGRHWQESGHFPRVSFCDINVR-ELGNIHHWSLQCVLMVNMFNEKIFIFLWFWFAFLLVATAGDFVIWVWRRFDSNSKLGFI--LDLLNQEGIDHSPQKASELYKNVLRDDGVLFLRLLDSNSGRLNSEELMKKIYNISVGHATDL 361
BLAST of innexin-1 vs. UniProt/SwissProt
Match: sp|A8WVX4|INX19_CAEBR (Innexin-19 OS=Caenorhabditis briggsae OX=6238 GN=inx-19 PE=3 SV=3) HSP 1 Score: 152.525 bits (384), Expect = 5.051e-39 Identity = 110/386 (28.50%), Postives = 179/386 (46.37%), Query Frame = 2 Query: 473 GVYDIFDRCVYILTFTLLLVCSATVTIKSYVLEPMTCYAPSTISGSNVLPYINNYCWIVGTIPKAVHEHNTDDEEYWKWLESRKINYYQWVPFVLGLQAALLYIPYVFWECLIYNRLGTNLQFLIDLA--RKASLDFGESRQRKISQMAGSIFILLTTRKKKSE-KAIGLLSKFPIYKME----IVFHYLLLKVISIVMICSQFVIMEKLLNMNGKHKLFGITVLQDLLNGRYWDVTNLFPRMAFCRVPFKMQNTNVVNITTQCSLSINLINEKIFIFLWWWFSLIASLQIISLFIWIARCLSSDRRVRFINHSAQISRSFP--------------------SHNEHLIKQFERNLISIDGIFLIHMTRINCGDLICNELIHKLYE 1549 G D DR Y T +L VC ++ K Y P+ C+ + S ++ YI +YCWI T ++E+ DD E ++I YYQWVPF+L +A + +P +FW + G N+Q LI+ A +A LD+ + RQ+ + + + L + +A G +++ + I Y K++ V + +QF I+ L + + FG VL D+ GR W T FPR+ C + N+ T QC+L IN+INEK+F FLW W+ ++A + S WIA +V ++ QI+ S + HL+ F + + DGI ++ M + GD+I +L+ L++ Sbjct: 19 GDDDAVDRLNYYYTPLILAVCCLVISAKQYGGTPIECWV-NPHSRESMEEYIESYCWIQNTYWIPMYENVPDDHTA---REEKQIGYYQWVPFILIAEALMFSLPCIFWRLCSFQS-GLNIQTLINAACDAQALLDYSD-RQKAVEAITCNFVDNLDLQSPNGRIRARGWIARIKFSRFLSGQCISIVYSFTKLLYSVNVVAQFFILNACLK-SSEFVFFGFQVLSDIWAGRPWTETGHFPRVTLCDFEVRYL-ANLNRYTVQCALLINIINEKVFAFLWCWYMILAIITTCSFIYWIANSFIHSEKVDYVMKFIQIAESSEYKKLQKFEKDATVERLYTVIAFAPHLLDSFVSDFLKSDGILMLRMISNHAGDMIVVQLVRNLWQ 396
BLAST of innexin-1 vs. UniProt/SwissProt
Match: sp|O01634|INX12_CAEEL (Innexin-12 OS=Caenorhabditis elegans OX=6239 GN=inx-12 PE=1 SV=1) HSP 1 Score: 150.984 bits (380), Expect = 1.141e-38 Identity = 106/377 (28.12%), Postives = 176/377 (46.68%), Query Frame = 2 Query: 482 DIFDRCVYILTFTLLLVCSATVTIKSYVLEPMTCYAPSTISGSNVLPYINNYCWIVGTIPKAVHEHNTDDEEYWKWL-----------ESRKINYYQWVPFVLGLQAALLYIPYVFWECLIYNRLGTNLQFLIDLARKASLDFGESRQRKISQMAGSIFILLTTRKKKSEKAIGLLSKFP--IYKMEIVFHYLLLKVISIVMICSQFVIMEKLLNMNGKHKLFGITVLQDLLNGRYWDVTNLFPRMAFCRVPFKMQN-TNVVNITTQCSLSINLINEKIFIFLWWWFSLIASLQIISLFIWIARCLSSDRRVRFINHSAQISRSFPSHNEHLIKQFERNLISIDGIFLIHMTRINCGDLICNELIHKLYEIHATSLA 1570 D D+ Y T L++ SA +T S+V P+ C+ P+ G Y +YC++ T E + W+ L ++ +I YYQWVPF+L LQA L Y P V W L Y G N+ L + A+ ESR+ I+ +AG I ++K+ + LS F ++ YL +K + ++ + QFV+++++L ++ +G V DL +G W T FPR+ C ++++N N+ + QC L IN+ NEKIF+ LWWW + + I + W R + FI + +N ++QF +S D +F++ + +N G ELI ++ T++ Sbjct: 18 DFVDKLNYCATTIGLVLASAFITGWSFVGSPIDCWFPAYYKGW-WAEYALDYCYVQNTFFVPFSEDKAERSYNWEQLVADKQNTTSLKQTNQIGYYQWVPFILALQAMLFYFPVVIWR-LFYGMAGQNVTSLCNTC-TATEGNEESRKGTITTIAGYI-----SQKRHRNLIVKQLSGFQNRANGSAVITSYLFMKALFLINVLFQFVLLKRMLGVD--SYFWGAEVTSDLWSGNEWPETGNFPRVTMCE--YEVRNLDNIHKHSVQCVLMINMFNEKIFVALWWWLCFLTVVTITNTIYWFWRASGTSVSKNFIRPYVEDIDPKVKNNRGKLQQFVSEFLSPDTVFILRLIELNNGKTPVVELIRDMWRRFNTAVP 382
BLAST of innexin-1 vs. TrEMBL
Match: I1ZIL2 (Innexin OS=Schmidtea mediterranea OX=79327 GN=inx PE=2 SV=1) HSP 1 Score: 843.958 bits (2179), Expect = 0.000e+0 Identity = 407/412 (98.79%), Postives = 412/412 (100.00%), Query Frame = 2 Query: 416 MVFKEFLDYLNKFNFIHACGVYDIFDRCVYILTFTLLLVCSATVTIKSYVLEPMTCYAPSTISGSNVLPYINNYCWIVGTIPKAVHEHNTDDEEYWKWLESRKINYYQWVPFVLGLQAALLYIPYVFWECLIYNRLGTNLQFLIDLARKASLDFGESRQRKISQMAGSIFILLTTRKKKSEKAIGLLSKFPIYKMEIVFHYLLLKVISIVMICSQFVIMEKLLNMNGKHKLFGITVLQDLLNGRYWDVTNLFPRMAFCRVPFKMQNTNVVNITTQCSLSINLINEKIFIFLWWWFSLIASLQIISLFIWIARCLSSDRRVRFINHSAQISRSFPSHNEHLIKQFERNLISIDGIFLIHMTRINCGDLICNELIHKLYEIHATSLANRGDDLSDSISHSSVYKAKDIETTMFI 1651 MVFKEFLDYLNKFNFIHACGVYDIFDRCVYILTFTLLLVCSATVTIKSYVLEPMTCYAPSTISGSNVLPYINNYCWIVGTIPKAVHEHN+DDEEYWKWLESRKINYYQWVPFVLGLQAALLYIPYVFWECLIYNRLGTNLQFLIDLARKASLDFGESRQRKISQMAGSIFILLTTRKKKSEKAIGLLSKFPIYKMEIVFHYLLLKVISIVMICSQFVIMEKLLNMNGKHKLFGITVLQDLLNGRYWDVTNLFPRMAFCRVPFKMQNTNVVNITTQCSLSINLINEKIF+FLWWWFSLIASLQIISLFIW+ARCLSSDRRVRFINHSAQISRSFPSH+EHLIKQF+RNLISIDGIFLIHMTRINCGDLICNELIHKLYEIHATSLANRGDDLSDSISHSSVYKAKDIETTMFI Sbjct: 1 MVFKEFLDYLNKFNFIHACGVYDIFDRCVYILTFTLLLVCSATVTIKSYVLEPMTCYAPSTISGSNVLPYINNYCWIVGTIPKAVHEHNSDDEEYWKWLESRKINYYQWVPFVLGLQAALLYIPYVFWECLIYNRLGTNLQFLIDLARKASLDFGESRQRKISQMAGSIFILLTTRKKKSEKAIGLLSKFPIYKMEIVFHYLLLKVISIVMICSQFVIMEKLLNMNGKHKLFGITVLQDLLNGRYWDVTNLFPRMAFCRVPFKMQNTNVVNITTQCSLSINLINEKIFLFLWWWFSLIASLQIISLFIWVARCLSSDRRVRFINHSAQISRSFPSHSEHLIKQFDRNLISIDGIFLIHMTRINCGDLICNELIHKLYEIHATSLANRGDDLSDSISHSSVYKAKDIETTMFI 412
BLAST of innexin-1 vs. TrEMBL
Match: A0A068W6W1 (Innexin OS=Echinococcus granulosus OX=6210 GN=inx PE=3 SV=1) HSP 1 Score: 346.665 bits (888), Expect = 8.207e-110 Identity = 168/405 (41.48%), Postives = 253/405 (62.47%), Query Frame = 2 Query: 416 MVFKEFLDYLNKFNFIHACGVYDIFDRCVYILTFTLLLVCSATVTIKSYVLEPMTCYAPSTISGSNVLPYINNYCWIVGTIPKAVHEHNTDDEEYWKWLESRKINYYQWVPFVLGLQAALLYIPYVFWECLIYNRLGTNLQFLIDLARKASLDFGESRQRKISQMAGSIFILLTTRKKKSEKA-----IGLLSKF----PIYKM--EIVFHYLLLKVISIVMICSQFVIMEKLLNMNGKHKLFGITVLQDLLNGRYWDVTNLFPRMAFCRVPFKMQNTNVVNITTQCSLSINLINEKIFIFLWWWFSLIASLQIISLFIWIARCLSSDRRVRFINHSAQISRSFPSHNEHLIKQFERNLISIDGIFLIHMTRINCGDLICNELIHKLYEIHATSLANRGDDLSDS 1597 MV +EFL L+K +F+ + ++D DRC Y+L+F +LL+C VT+KSYV EP +CY +T SGSN++ YIN++CW+ GT+P V+ + DD YW +LES+K+NYYQWV VL QA L Y P + WE L +NR+GTN+ F ++ A+ A+ + G +R+ +I +A ++ LL R+ S + G+ F P +M I +YL++K++ Q VIME+ L M HKLFG+ +L DL +GRYW T +FPR+ +CRVP K+ NV + QC++ +N++NEKI+IFLW+WF +A+LQ IS+ W R RRV+ + H +I+ ++ +K+FE + DG FL+HM R+N GD+I NELI L+E + R + L+D+ Sbjct: 1 MVAQEFLSQLDKLHFVDSANLHDFADRCAYLLSFIILLMCFTIVTLKSYVFEPFSCYTATTFSGSNMISYINSFCWVNGTVPADVNTNRLDDPVYWDYLESKKLNYYQWVSLVLAFQAILCYFPSLLWEGLTFNRIGTNINFYVEFAQGAAKETGINRKNRIQFLASALDTLLFARRPLSHRPHSSLCYGIAEFFGELLPRKRMGRAICAYYLVIKLLYFANAVLQLVIMERFLGMPDSHKLFGVQILLDLWHGRYWQATLIFPRVGYCRVPIKLVGRNVPTLIAQCTMPVNMLNEKIYIFLWFWFVAVATLQAISIITWTLRLSMRKRRVKALIHYLKIAEAYDQGMRETLKRFEATCLRPDGTFLLHMLRLNAGDIITNELIQALFERYI-----RHEKLADA 400
BLAST of innexin-1 vs. TrEMBL
Match: W6UDL6 (Innexin OS=Echinococcus granulosus OX=6210 GN=inx PE=3 SV=1) HSP 1 Score: 346.665 bits (888), Expect = 2.059e-109 Identity = 165/389 (42.42%), Postives = 246/389 (63.24%), Query Frame = 2 Query: 416 MVFKEFLDYLNKFNFIHACGVYDIFDRCVYILTFTLLLVCSATVTIKSYVLEPMTCYAPSTISGSNVLPYINNYCWIVGTIPKAVHEHNTDDEEYWKWLESRKINYYQWVPFVLGLQAALLYIPYVFWECLIYNRLGTNLQFLIDLARKASLDFGESRQRKISQMAGSIFILLTTRKKKSEKA-----IGLLSKF----PIYKM--EIVFHYLLLKVISIVMICSQFVIMEKLLNMNGKHKLFGITVLQDLLNGRYWDVTNLFPRMAFCRVPFKMQNTNVVNITTQCSLSINLINEKIFIFLWWWFSLIASLQIISLFIWIARCLSSDRRVRFINHSAQISRSFPSHNEHLIKQFERNLISIDGIFLIHMTRINCGDLICNELIHKLYE 1549 MV +EFL L+K +F+ + ++D DRC Y+L+F +LL+C VT+KSYV EP +CY +T SGSN++ YIN++CW+ GT+P V+ + DD YW +LES+K+NYYQWV VL QA L Y P + WE L +NR+GTN+ F ++ A+ A+ + G +R+ +I +A ++ LL R+ S + G+ F P +M I +YL++K++ Q VIME+ L M HKLFG+ +L DL +GRYW T +FPR+ +CRVP K+ NV + QC++ +N++NEKI+IFLW+WF +A+LQ IS+ W R RRV+ + H +I+ ++ +K+FE + DG FL+HM R+N GD+I NELI L+E Sbjct: 1 MVAQEFLSQLDKLHFVDSANLHDFADRCAYLLSFIILLMCFTIVTLKSYVFEPFSCYTATTFSGSNMISYINSFCWVNGTVPADVNTNRLDDPVYWDYLESKKLNYYQWVSLVLAFQAILCYFPSLLWEGLTFNRIGTNINFYVEFAQGAAKETGINRKNRIQFLASALDTLLFARRPLSHRPHSSLCYGIAEFFGELLPRKRMGRAICAYYLVIKLLYFANAVLQLVIMERFLGMPDSHKLFGVQILLDLWHGRYWQATLIFPRVGYCRVPIKLVGRNVPTLIAQCTMPVNMLNEKIYIFLWFWFVAVATLQAISIITWTLRLSMRKRRVKALIHYLKIAEAYDQGMRETLKRFEATCLRPDGTFLLHMLRLNAGDIITNELIQALFE 389
BLAST of innexin-1 vs. TrEMBL
Match: A0A068Y5E6 (Innexin OS=Echinococcus multilocularis OX=6211 GN=inx PE=3 SV=1) HSP 1 Score: 345.51 bits (885), Expect = 2.593e-109 Identity = 172/429 (40.09%), Postives = 258/429 (60.14%), Query Frame = 2 Query: 416 MVFKEFLDYLNKFNFIHACGVYDIFDRCVYILTFTLLLVCSATVTIKSYVLEPMTCYAPSTISGSNVLPYINNYCWIVGTIPKAVHEHNTDDEEYWKWLESRKINYYQWVPFVLGLQAALLYIPYVFWECLIYNRLGTNLQFLIDLARKASLDFGESRQRKISQMAGSIFILLTTRKKKSEKA-----------IGLLSKFPIYKMEIVFHYLLLKVISIVMICSQFVIMEKLLNMNGKHKLFGITVLQDLLNGRYWDVTNLFPRMAFCRVPFKMQNTNVVNITTQCSLSINLINEKIFIFLWWWFSLIASLQIISLFIWIARCLSSDRRVRFINHSAQISRSFPSHNEHLIKQFERNLISIDGIFLIHMTRINCGDLICNELIHKLYEIH--------ATSLANRGDDLSDSISHSSVYKAKDIETTM 1645 MV +EFL L+K +F+ + ++D DRC Y+L+F +LL+C VT+KSYV EP +CY +T SGSN++ YIN++CW+ GT+P V+ + DD YW +LES+K+NYYQWV VL QA L Y P + WE L +NR+GTN+ F ++ A+ A+ + G +R+ +I +A ++ LL R+ S + G L I +YL++K++ Q VIME+ L M HKLFG+ +L DL +GRYW T +FPR+ +CRVP K+ NV + QC++ +N++NEKI+IFLW+WF +A+LQ IS+ W R RRV+ + H +I+ ++ +K+FE + DG FL+HM R+N GD+I NELI L+E + A+S+ G S + S+ AKD E ++ Sbjct: 1 MVAQEFLSQLDKLHFVDSANLHDFADRCAYLLSFIILLMCFTIVTLKSYVFEPFSCYTATTFSGSNMISYINSFCWVNGTVPADVNTNRLDDPVYWDYLESKKLNYYQWVSLVLAFQAILCYFPSLLWEGLTFNRIGTNINFYVEFAQGAAKETGINRKNRIQFLASALDTLLFARRPLSHRPHNSLCYGIAEFFGELLPRKRLGRAICAYYLVIKLLYFANAVLQLVIMERFLGMPDSHKLFGVQILLDLWHGRYWQSTLIFPRVGYCRVPIKLVGRNVPTLIAQCTMPVNMLNEKIYIFLWFWFVAVATLQAISIITWTLRLSMRKRRVKALIHYLKIAEAYDQGMRETLKRFEATCLRPDGTFLLHMLRLNAGDIITNELIQALFERYIRHEKLAGASSIREVGSASVSSPNPSA--DAKDDEGSV 427
BLAST of innexin-1 vs. TrEMBL
Match: A0A4E0QYX2 (Innexin OS=Fasciola hepatica OX=6192 GN=inx PE=3 SV=1) HSP 1 Score: 343.199 bits (879), Expect = 3.196e-108 Identity = 163/425 (38.35%), Postives = 258/425 (60.71%), Query Frame = 2 Query: 416 MVFKEFLDYLNKFNFIHACGVYDIFDRCVYILTFTLLLVCSATVTIKSYVLEPMTCYAPSTISGSNVLPYINNYCWIVGTIPKAVHEHNTDDEEYWKWLESRKINYYQWVPFVLGLQAALLYIPYVFWECLIYNRLGTNLQFLIDLARKASLDFGESRQRKISQMAGSIFILLTTR---KKKSEKAIGLLSKFPIY-------------KMEIVFHYLLLKVISIVMICSQFVIMEKLLNMNGKHKLFGITVLQDLLNGRYWDVTNLFPRMAFCRVPFKMQNTNVVNITTQCSLSINLINEKIFIFLWWWFSLIASLQIISLFIWIARCLSSDRRVRFINHSAQISRSFPSHNEHLIKQFERNLISIDGIFLIHMTRINCGDLICNELIHKLY----EIHATSLANRGDDLSDSISHSSVYKAKD 1630 MV EF+ L+K F+ + G+ D DRC Y+L+F LL++C VT+KSYV EPM+CY P+T SGSN+ PYIN +CWI GT P + DD+EYW LE +KINYYQWV VL LQA L Y+P + W+ + YNR+GTNL FLI+ A+ AS + G+ R ++ +A + LL R +K+S + + IY +V +Y+L+K + ++ Q +M++ L + G+++LFG+++L DLL GR+W+ T++FPR+ FCRVP K+ +T + +T QC+L +N++NEK+++FLW+WF +ASL++ S+ +W+ R + R+R + +I+ ++ + L+ +FE + +DG F++ M R+N G L+ E++ + E S+A + HS KA D Sbjct: 1 MVALEFISQLDKLRFVDSVGLDDFADRCSYMLSFALLVICFTIVTLKSYVFEPMSCYVPTTFSGSNLGPYINAFCWINGTTPMSADTDRLDDQEYWNSLEDKKINYYQWVSLVLALQAILCYVPRLIWDTITYNRVGTNLGFLIESAQAASKETGKERSNRVQFVASVMDTLLFARRDLRKRSTDCPEMHNPLIIYMRVVRDLFPRKRLGTALVSYYMLVKGLYLLNAVGQLFLMQRFLGVRGEYQLFGLSILNDLLMGRHWNETSVFPRIGFCRVPIKLTSTPIPMVTVQCTLPVNMLNEKVYVFLWFWFVFVASLEVASVTVWVYRLAARQSRLRTLVRYLKIADAYDEGMDPLLTRFEMTFLRLDGSFILQMMRLNAGSLVTQEILQAMLKRYTEQEEYSIAQQKRKERQQHEHSLSQKAPD 425
BLAST of innexin-1 vs. Ensembl Cavefish
Match: panx2 (pannexin 2 [Source:NCBI gene;Acc:103040952]) HSP 1 Score: 50.0618 bits (118), Expect = 6.451e-6 Identity = 38/158 (24.05%), Postives = 67/158 (42.41%), Query Frame = 2 Query: 488 FDRCVYILTFTLLLVCSATVTIKSYVLEPMTCYAPSTISGSNVLPYINNYCW--IVGTIPKAVHEHNTDDEEYWKWLESRKINYYQWVPFVLGLQAALLYIPYVFWECLIYNRLGTNLQFLIDLARKASLDFGESRQRKISQMAGSIFILLTTRKKKS 955 FDR V I T + ++ V +++ E + CY P + L Y YCW + +P + ++ E ++++P+ L A ++YIP + WE L RL + L FL+ E R KI + S ++ R+++ Sbjct: 51 FDRVVTIGTVIIPILLVTLVFTRNFAEESIYCYTPHNFTRDQAL-YARGYCWTELRDAVP------GVEPQQRPSLFE------HKFLPYALLAFAGIMYIPALGWEFLASTRLTSELNFLLQEIDNCYHRAAEGRAPKIEKQIQSKGPGISERERRE 195
BLAST of innexin-1 vs. Ensembl Medaka
Match: panx2 (pannexin 2 [Source:NCBI gene;Acc:101160161]) HSP 1 Score: 52.7582 bits (125), Expect = 1.048e-6 Identity = 44/157 (28.03%), Postives = 66/157 (42.04%), Query Frame = 2 Query: 488 FDRCVYILTFTLLLVCSATVTIKSYVLEPMTCYAPSTISGSNVLPYINNYCW--IVGTIPKAVHEHNTDDEEYWKWLESRKINYYQWVPFVLGLQAALLYIPYVFWECLIYNRLGTNLQFLIDLARKASLDFGESRQRKISQMAGSIFILLTTRKKK 952 FDR V I T + ++ V +++ E + CY P + L Y YCW + IP V H W L K ++P+ L A ++YIP + WE L RL + L FL+ E R KI + S +T R+++ Sbjct: 51 FDRVVTIGTVIIPILLVTLVFTRNFAEESIYCYTPHNFTRDQAL-YARGYCWTELRDAIP-GVEPH------LWPSLFEHK-----FLPYALLAFAGIMYIPALGWEFLASTRLTSELNFLLQEIDNCYHRAAEGRAPKIEKQIQSKGPGITERERR 194
BLAST of innexin-1 vs. Ensembl Medaka
Match: panx3 (pannexin 3 [Source:NCBI gene;Acc:101163377]) HSP 1 Score: 51.6026 bits (122), Expect = 1.800e-6 Identity = 36/130 (27.69%), Postives = 64/130 (49.23%), Query Frame = 2 Query: 521 LLLVCSATVTIKSYVLEP-MTCYAPSTISGSNVLPYINNYCWIVGTIPKAVHEHNTDDEEYWKWLESRKINYYQWVPFVLGLQAALLYIPYVFWECLIYNRLGTNLQFLIDLARKASLDFGESRQRKISQ 907 L+LVC A V + L P ++C+ PS + Y++ YCW ++ H D + + E + + ++ P+ L A L+Y+P + W L+ LG++L F+ID LD +R +++Q Sbjct: 49 LMLVCMAFV--REISLGPQISCFTPSNFTAKQA-SYVDTYCW------DSLMHHEFDSDGNF---EEQSLWVHKMFPYSLMAMAILMYLPALIWRQLVMPTLGSDLLFIID-----ELDKSYNRSIRLAQ 161
BLAST of innexin-1 vs. Planmine SMEST
Match: SMESG000043134.1 (SMESG000043134.1) HSP 1 Score: 835.484 bits (2157), Expect = 0.000e+0 Identity = 403/412 (97.82%), Postives = 410/412 (99.51%), Query Frame = 2 Query: 416 MVFKEFLDYLNKFNFIHACGVYDIFDRCVYILTFTLLLVCSATVTIKSYVLEPMTCYAPSTISGSNVLPYINNYCWIVGTIPKAVHEHNTDDEEYWKWLESRKINYYQWVPFVLGLQAALLYIPYVFWECLIYNRLGTNLQFLIDLARKASLDFGESRQRKISQMAGSIFILLTTRKKKSEKAIGLLSKFPIYKMEIVFHYLLLKVISIVMICSQFVIMEKLLNMNGKHKLFGITVLQDLLNGRYWDVTNLFPRMAFCRVPFKMQNTNVVNITTQCSLSINLINEKIFIFLWWWFSLIASLQIISLFIWIARCLSSDRRVRFINHSAQISRSFPSHNEHLIKQFERNLISIDGIFLIHMTRINCGDLICNELIHKLYEIHATSLANRGDDLSDSISHSSVYKAKDIETTMFI 1651 MVFKEFLDYLNKFNFIHACGVYDIFDRCVYILTFTLLLVCSATVTIKSYVL+PMTCYAPSTISGSNVL YINNYCWIVGTIPKAVHEHN+DDEEYWKWLESRKINYYQWVPFVLGLQAALLYIPYVFWECLIYNRLGTNLQFLIDLARKASLDFGESRQRKISQMAGSIFILLTTRKKKSEKAIGLLSKFPIYKMEIVFHYLLLKVIS+VMICSQFVIMEKLLNMNGKHKLFGITVLQDLLNGRYWDVTNLFPRMAFCRVPFKMQNTNVVNITTQCSLSINLINEKIFIFLWWWFSLIASLQIISLFIW+ARCLSSDRRVRFINHSAQISRSFP H+EHLIKQF+RNLISIDGIFLIH+TRINCGDLICNELIHKLYEIHATSLANRGDDLSDSISHSSVYKAKDIETTMFI Sbjct: 1 MVFKEFLDYLNKFNFIHACGVYDIFDRCVYILTFTLLLVCSATVTIKSYVLKPMTCYAPSTISGSNVLQYINNYCWIVGTIPKAVHEHNSDDEEYWKWLESRKINYYQWVPFVLGLQAALLYIPYVFWECLIYNRLGTNLQFLIDLARKASLDFGESRQRKISQMAGSIFILLTTRKKKSEKAIGLLSKFPIYKMEIVFHYLLLKVISVVMICSQFVIMEKLLNMNGKHKLFGITVLQDLLNGRYWDVTNLFPRMAFCRVPFKMQNTNVVNITTQCSLSINLINEKIFIFLWWWFSLIASLQIISLFIWVARCLSSDRRVRFINHSAQISRSFPPHSEHLIKQFDRNLISIDGIFLIHVTRINCGDLICNELIHKLYEIHATSLANRGDDLSDSISHSSVYKAKDIETTMFI 412
BLAST of innexin-1 vs. Planmine SMEST
Match: SMESG000065083.1 (SMESG000065083.1) HSP 1 Score: 256.144 bits (653), Expect = 1.826e-78 Identity = 149/420 (35.48%), Postives = 232/420 (55.24%), Query Frame = 2 Query: 416 MVFKEFLDYLNKFNFIHACGVYDIFDRCVYILTFTLLLVCSATVTIKSYVLEPMTCYAPSTISGSNVLPYINNYCWIVGTIPKAVHEHNTDDEEYWKWLESRKINYYQWVPFVLGLQAALLYIPYVFWECLIYNRLGTNLQFLIDLARKASLDFGESRQRKISQMAGSIFILLTTR-----------KKKSEKAIGLLSKFPIYKMEIVFHYLLLKVISIVMICSQFVIMEKLLNMNGKHKL-FGITVLQDLLNGRYWDVTNLFPRMAFCRVPFKMQNTNVVN-ITTQCSLSINLINEKIFIFLWWWFSLIASLQIISLFIWIARCLSSDRRVRFINHSAQISRSFPSHNE--HLIKQFERNLISIDGIFLIHMTRINCGDLICNELIHKLYEIHATSLANR-----GDDLSDSISHSSV 1615 MV EFLDYL+K G+ D+ DR + + +L+VC VT+K YV +P++CY P+ I GSN+L Y+ N CW+ GTI + +E WK LE K+ YYQWVPF+LGLQ + Y+P + W+ + YNR GT++Q L+ A +A E+R + +S ++ ++ LL ++K ++G L +V YLLLK+ + Q +IM+K L + + L FGI V ++ +G W T +FPR+++C V K+ + V+N + QC L +N++NE+I+ FLW W ++ SL I+S+ IWI R L R FI IS + +L+ +FE + DGIFL+ M +N GD+I +E++ +L+ I+ T+ NR G D D S + + Sbjct: 1 MVASEFLDYLSKLQVSTNVGLEDLPDRLNFTFSVIVLMVCILIVTVKQYVFKPISCYLPNNIGGSNLLSYVENLCWVQGTIALSNQAKFPSTDEEWKNLEKHKMLYYQWVPFMLGLQCIMFYVPKLVWQIICYNRTGTDIQHLVVSANQAVHSSDEARSKMVSYLSKTLEQLLYQHRDHRSGKLAKFRRKIHNSVGFLMCSKRIGTWLVSSYLLLKLSYVANGFIQLIIMQKFLGFSDFNLLTFGIEVGNNIWSGTDWKTTLIFPRVSYCFV--KVTHLGVINSMVAQCVLPVNMLNERIYFFLWCWILIVLSLTILSIPIWILRILCIKYRRHFIRQFLIISEEITKDQKENYLLAKFESQFLRHDGIFLLKMISLNAGDIITSEIVCQLWNIYKTNYVNRNFLNDGSDEDDDKSRTMI 418
BLAST of innexin-1 vs. Planmine SMEST
Match: SMESG000081749.1 (SMESG000081749.1) HSP 1 Score: 242.662 bits (618), Expect = 1.173e-73 Identity = 137/394 (34.77%), Postives = 221/394 (56.09%), Query Frame = 2 Query: 425 KEFLDYLNKFNFIHACGVYDIFDRCVYILTFTLLLVCSATVTIKSYVLEPMTCYAPSTISGSNVLPYINNYCWIVGTIPKAVHEHNTDDEEYWKWLE-SRKINYYQWVPFVLGLQAALLYIPYVFWECLIYNRLGTNLQFLIDLARKASLDFGESRQRKISQMAGSIFILLTTRKKKSEKAIGLLSKFPIYKMEI----------VFH---YLLLKVISIVMICSQFVIMEKLLNMNGKHKL---FGITVLQDLLNGRYWDVTNLFPRMAFCRVPFKMQNTNVVNITTQCSLSINLINEKIFIFLWWWFSLIASLQIISLFIWIARCLSSDRRVRFINHSAQISRSFPSHNEHLIKQFERNLISIDGIFLIHMTRINCGDLICNELIHKLYEIH 1555 + FL F G+ D D+ ++ + +L+VCS V+ K Y+ ++CY P +SG ++ Y+ NYCW+ GTIP +E ++ W + SRKINYYQWVPFVLGLQ L Y+P + W+ +IYN G +L+ L+ A+KAS GE R+ I Q+A + L R+ +KFP+ + ++ VF Y+++K++ + Q ++M+ L G KL FG T+L+D+L+G+ W+ LFPR++FC + T+ + QC+L IN++NEKI+IFLW+W + L IIS+ +W+ R +R FI +I ++ ++LI QF + DGIF++H+ +N GDLI +++ +L+EI+ Sbjct: 2 ETFLSQFTAFQAGKYVGIEDAADKASFLFSVIILVVCSVIVSTKQYITADISCYIPVVLSGVDLDKYVKNYCWVHGTIPFYANETLPQTKDEWIIADASRKINYYQWVPFVLGLQGVLFYLPRLIWKTIIYNLSGNDLEGLVVSAKKASNQVGEIRKETILQVAKCLEDLFLQRRVLGH------TKFPVLRQKMSLICCGRRTGVFFISLYIVIKLLYLTNAICQIILMQNFLKY-GVSKLNAAFGWTILKDILSGKQWNDNLLFPRVSFCFISDISTVTHKNHHIAQCALPINMLNEKIYIFLWFWTVGVLFLTIISIPLWLYRMTFFRKRKDFIKRFLKIKSAYTKDKKNLISQFVEQFLRHDGIFILHIISLNAGDLIATDIVSELWEIY 388
BLAST of innexin-1 vs. Planmine SMEST
Match: SMESG000080788.1 (SMESG000080788.1) HSP 1 Score: 242.662 bits (618), Expect = 2.160e-73 Identity = 128/393 (32.57%), Postives = 221/393 (56.23%), Query Frame = 2 Query: 416 MVFKEFLDYLNKFNFIHACGVYDIFDRCVYILTFTLLLVCSATVTIKSYVLEPMTCYAPSTISGSNVLPYINNYCWIVGTIPKAVHEH-NTDDEEYWKWLESRKINYYQWVPFVLGLQAALLYIPYVFWECLIYNRLGTNLQFLIDLARKASLDFGESRQRKISQMAGSIFILLTTRKKKSEKAIGLLSK-------FPIYKME----IVFHYLLLKVISIVMICSQFVIMEKLLNMNGKHKLFGITVLQDLLNGRYWDVTNLFPRMAFCRVPFKMQNTNVVN-ITTQCSLSINLINEKIFIFLWWWFSLIASLQIISLFIWIARCLSSDRRVRFINHSAQISRSFPSHNEHLIKQFERNLISIDGIFLIHMTRINCGDLICNELIHKLYEIH 1555 MV +EFL+ + +F G+ D D+ ++ + TLL++ VTIKSY+ +P+ CY + GSN Y+ NYCW+ GTI E +D ++ + ++R+INYYQWVPF+LGLQ + YIP + W+ + YN+ GTNL+ +++ A A+ R+ KI ++A +I +L + + L + F ++ ++ Y+L+K + + + Q IM+K L N FG TVL ++++G+ W T +FPR+ +C V +++ V N QC+L +N++NEKI++FLW+W L+ + IS+ +W R RR +FI + +++ ++ +I F + DG+FL+ M IN GD+I +++++L EI+ Sbjct: 1 MVAEEFLNLIGQFKISTYVGIEDFADKLSFLFSVTLLILSMMVVTIKSYLFKPLACYTATAPGGSNFENYLENYCWVHGTITFLPGEDIPQNDVDWARADDTRRINYYQWVPFILGLQCFMFYIPKIIWQIICYNKSGTNLESIVNDANAANNTPPVERKDKIERIARTIEDMLFQHRDYRQGNFAKLRRKIYNTCNFCVFSKHMGTWLILSYILIKFLYGLNVIGQLFIMKKFLGFNNSTSSFGYTVLSNMISGKEWHQTGIFPRVTYCYVR-NIKHVGVANKYVAQCALPVNMLNEKIYVFLWFWMVLVGIVTAISIPLWFYRMAFLSRRSKFIKRFLMMHQNYERSDKPMINNFIEEFLRHDGVFLVRMLFINAGDIITADIVNRLLEIY 392
BLAST of innexin-1 vs. Planmine SMEST
Match: SMESG000081749.1 (SMESG000081749.1) HSP 1 Score: 234.187 bits (596), Expect = 2.098e-70 Identity = 134/390 (34.36%), Postives = 217/390 (55.64%), Query Frame = 2 Query: 443 LNKFNFIHACGVYDIFDRCVYILTFTLLLVCSATVTIKSYVLEPMTCYAPSTISGSNVLPYINNYCWIVGTIPKAVHEHNTDDEEYWKWLES---RKINYYQWVPFVLGLQAALLYIPYVFWECLIYNRLGTNLQFLIDLARKASLDFGESRQRKISQMAGSIFILLTTRKKKSEKAIGLLSKFPIYKMEI----------VFH---YLLLKVISIVMICSQFVIMEKLLNMNGKHKL---FGITVLQDLLNGRYWDVTNLFPRMAFCRVPFKMQNTNVVNITTQCSLSINLINEKIFIFLWWWFSLIASLQIISLFIWIARCLSSDRRVRFINHSAQISRSFPSHNEHLIKQFERNLISIDGIFLIHMTRINCGDLICNELIHKLYEIH 1555 + FN GV D D+ ++ + +L+VC+ V+ K Y+ + CY P +G + YI NYCW GTIP E+ T + W+++ R++NYYQWVPFVLGLQ L Y+P + W+ +IYN G +L+ L+ A+KAS GE R+ I Q+A + L R+ +KFP+ + ++ VF Y+++K++ + Q ++M+ L G KL FG T+L+D+L+G+ W+ LFPR++FC + T+ + QC+L IN++NEKI+IFLW+W + L IIS+ +W+ R +R FI +I ++ ++LI QF + DGIF++H+ +N GDLI +++ +L+EI+ Sbjct: 8 FSNFNVEKYVGVEDGADKASFLFSVVILVVCTVIVSTKQYIFGEIACYIPILNTGEKLEDYIQNYCWAHGTIP--FRENETLPQNRKDWMQADFDRRLNYYQWVPFVLGLQGVLFYLPRLIWKTIIYNLSGNDLEGLVVSAKKASNQVGEIRKETILQVAKCLEDLFLQRRVLGH------TKFPVLRQKMSLICCGRRTGVFFISLYIVIKLLYLTNAICQIILMQNFLKY-GVSKLNAAFGWTILKDILSGKQWNDNLLFPRVSFCFISDISTVTHKNHHIAQCALPINMLNEKIYIFLWFWTVGVLFLTIISIPLWLYRMTFFRKRKDFIKRFLKIKSAYTKDKKNLISQFVEQFLRHDGIFILHIISLNAGDLIATDIVSELWEIY 388 The following BLAST results are available for this feature:
BLAST of innexin-1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 2
BLAST of innexin-1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of innexin-1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of innexin-1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 3
BLAST of innexin-1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 1
BLAST of innexin-1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 2
BLAST of innexin-1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of innexin-1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of innexin-1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 1
BLAST of innexin-1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 0
BLAST of innexin-1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of innexin-1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 0
BLAST of innexin-1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 2
BLAST of innexin-1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Cross References
External references for this transcript
Sequences
The following sequences are available for this feature:
transcript sequence >SMED30008787 ID=SMED30008787|Name=innexin-1|organism=Schmidtea mediterranea sexual|type=transcript|length=1879bpback to top protein sequence of SMED30008787-orf-1 >SMED30008787-orf-1 ID=SMED30008787-orf-1|Name=SMED30008787-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=413bp MVFKEFLDYLNKFNFIHACGVYDIFDRCVYILTFTLLLVCSATVTIKSYVback to top Aliases
The feature 'innexin-1' has the following synonyms
Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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