acetylcholine receptor subunit alpha-like

Query:  159 IVQGTKDARRLYDDLMRRRGYDPSVRPVKSYTSTVLLYMNLSLVQILDVDEKNQIIVLNMWVNQEWNDPNFVWDPNDYGNVTELNIPSREIWTPDLVLYNNAGGDWDLASSSNTKVIVNHDGSVLWKPPIIFKSQCGINVEFFPFDKQLCDLKIGTWTHNGFLIDLRHTAQKNQSQASFDNCNAKIDYAIDLSQYVNNVEWDLLEVSAKRNIEFYPCCTEPYLDISFNVSLRRRTLFYGINLICPCLAISFLTILVFYLPADSGEKXXXXXXXXXXXXXXXXXXXDISPPTSIVVPLILKYLLFTMILVTLSVMATVLVLNIHWRSPDTHKMAPWVRSVFTSTLPKLLFMKKPDQD--------------------YRDNETDDIPETF-----------HEDETDSNIQDKWSTRRAAVSGDNVVN------EIELALEGVRRIVHHIKKENSYSAMRDDWKYVAVVLDRLFLWLFSIAAIIGMLGIFMQAPTLTDNA 1544
            + + ++   RL++ L     Y+  +RPV + +  V+++  +S+ Q++ VDE NQI+  N+W+ Q WND    W+P+DYG    + +P+++IW PD+VLYNNA GD+ +     TK ++ + G V W PP IFKS C I+V +FPFD Q C +K G+W+++   IDL                   I  +++L  Y  + EW +++    ++   Y CC E Y DI++++ +RR  LFY INLI PCL ISFLT+LVFYLP+D GEKV+L IS+LLSLTVF L+I +  P TS+V+PLI +YLLFTMI VTLS++ TV VLN+H+R+P TH M  WV++VF + LP+++FM +P  +                    +   E+    E +           H     SN     +   ++ S D V++      EI+ A++ V+ I  ++K +N    ++DDWKYVA+V+DR+FLW+F++  I+G  G+F+Q     ++A
Sbjct:   28 VARASEAEHRLFERLFE--DYNEIIRPVANVSDPVIIHFEVSMSQLVKVDEVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQV--DDKTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDL-----------------VLIGSSMNLKDYWESGEWAIIKAPGYKHDIKYNCCEEIYPDITYSLYIRRLPLFYTINLIIPCLLISFLTVLVFYLPSDCGEKVTLCISVLLSLTVFLLVITETIPSTSLVIPLIGEYLLFTMIFVTLSIVITVFVLNVHYRTPTTHTMPSWVKTVFLNLLPRVMFMTRPTSNEGNAQKPRPLYGAELSNLNCFSRAESKGCKEGYPCQDGMCGYCHHRRIKISNFSANLTRSSSSESVDAVLSLSALSPEIKEAIQSVKYIAENMKAQNEAKEIQDDWKYVAMVIDRIFLWVFTLVCILGTAGLFLQPLMAREDA 505          

Query:  159 IVQGTKDARRLYDDLMRRRGYDPSVRPVKSYTSTVLLYMNLSLVQILDVDEKNQIIVLNMWVNQEWNDPNFVWDPNDYGNVTELNIPSREIWTPDLVLYNNAGGDWDLASSSNTKVIVNHDGSVLWKPPIIFKSQCGINVEFFPFDKQLCDLKIGTWTHNGFLIDLRHTAQKNQSQASFDNCNAKIDYAIDLSQYVNNVEWDLLEVSAKRNIEFYPCCTEPYLDISFNVSLRRRTLFYGINLICPCLAISFLTILVFYLPADSGEKXXXXXXXXXXXXXXXXXXXDISPPTSIVVPLILKYLLFTMILVTLSVMATVLVLNIHWRSPDTHKMAPWVRSVFTSTLPKLLFMKKPDQD--------------------YRDNETDDIPETF-----------HEDETDSNIQDKWSTRRAAVSGDNVVN------EIELALEGVRRIVHHIKKENSYSAMRDDWKYVAVVLDRLFLWLFSIAAIIGMLGIFMQAPTLTDNA 1544
            + + ++   RL++ L     Y+  +RPV + +  V+++  +S+ Q++ VDE NQI+  N+W+ Q WND    W+P+DYG    + +P+++IW PD+VLYNNA GD+ +     TK ++ + G V W PP IFKS C I+V +FPFD Q C +K G+W+++   IDL                   I  +++L  Y  + EW +++    ++   Y CC E Y DI++++ +RR  LFY INLI PCL ISFLT+LVFYLP+D GEKV+L IS+LLSLTVF L+I +  P TS+V+PLI +YLLFTMI VTLS++ TV VLN+H+R+P TH M  WV++VF + LP+++FM +P  +                    +   E+    E +           H     SN     +   ++ S D V++      EI+ A++ V+ I  ++K +N    ++DDWKYVA+V+DR+FLW+F++  I+G  G+F+Q     ++A
Sbjct:   28 VARASEAEHRLFERLFE--DYNEIIRPVANVSDPVIIHFEVSMSQLVKVDEVNQIMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQV--DDKTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDL-----------------VLIGSSMNLKDYWESGEWAIIKAPGYKHDIKYNCCEEIYPDITYSLYIRRLPLFYTINLIIPCLLISFLTVLVFYLPSDCGEKVTLCISVLLSLTVFLLVITETIPSTSLVIPLIGEYLLFTMIFVTLSIVITVFVLNVHYRTPTTHTMPSWVKTVFLNLLPRVMFMTRPTSNEGNAQKPRPLYGAELSNLNCFSRAESKGCKEGYPCQDGMCGYCHHRRIKISNFSANLTRSSSSESVDAVLSLSALSPEIKEAIQSVKYIAENMKAQNEAKEIQDDWKYVAMVIDRIFLWVFTLVCILGTAGLFLQPLMAREDA 505          

Query:  171 TKDARRLYDDLMRRRGYDPSVRPVKSYTSTVLLYMNLSLVQILDVDEKNQIIVLNMWVNQEWNDPNFVWDPNDYGNVTELNIPSREIWTPDLVLYNNAGGDWDLASSSNTKVIVNHDGSVLWKPPIIFKSQCGINVEFFPFDKQLCDLKIGTWTHNGFLIDLRHTAQKNQSQASFDNCNAKIDYAIDLSQYVNNVEWDLLEVSAKRNIEFYPCCTEPYLDISFNVSLRRRTLFYGINLICPCLAISFLTILVFYLPADSGEKXXXXXXXXXXXXXXXXXXXDISPPTSIVVPLILKYLLFTMILVTLSVMATVLVLNIHWRSPDTHKMAPWVRSVFTSTLPKLLFMKKPDQ--DYRDNETDDIPETFHEDETD---------SNIQDKWSTR----------------RAAVSG---DNVVNEIEL--------ALEGVRRIVHHIKKENSYSAMRDDWKYVAVVLDRLFLWLFSIAAIIGMLGIFM 1517
            T+   RL+  L R  GY+   RPV + +  V++   LS+ Q++DVDEKNQ++  N+W+ QEW+D    W+P D+GN+T L +PS  IW PD+VLYNNA G  + A +  TK  +   G+V W PP I+KS C I+V FFPFD+Q C +K G+WT++   IDL    Q                  +DL  Y  + EW ++  +   N + Y CC E Y D+++   +RR  LFY INLI PCL IS LT+LVFYLP+D GEK++L IS+LLSLTVF LLI +I P TS+V+PLI +YLLFTMI VTLS++ TV VLN+H RSP TH M  WVR      +P+ L M +P    +        +  ++H  E++            +D+W+                   +  SG   + ++ E EL        ALEGV  I  H++ E++ S++++DWKYVA+V+DR+FLWLF I   +G +G+F+
Sbjct:   34 TETEDRLFKHLFR--GYNRWARPVPNTSDVVIVRFGLSIAQLIDVDEKNQMMTTNVWLKQEWSDYKLRWNPTDFGNITSLRVPSEMIWIPDIVLYNNADG--EFAVTHMTKAHLFSTGTVHWVPPAIYKSSCSIDVTFFPFDQQNCKMKFGSWTYDKAKIDLEQMEQ-----------------TVDLKDYWESGEWAIVNATGTYNSKKYDCCAEIYPDVTYAFVIRRLPLFYTINLIIPCLLISCLTVLVFYLPSDCGEKITLCISVLLSLTVFLLLITEIIPSTSLVIPLIGEYLLFTMIFVTLSIVITVFVLNVHHRSPSTHTMPHWVRGALLGCVPRWLLMNRPPPPVELCHPLRLKLSPSYHWLESNVDAEEREVVVEEEDRWACAGHVAPSVGTLCSHGHLHSGASGPKAEALLQEGELLLSPHMQKALEGVHYIADHLRSEDADSSVKEDWKYVAMVIDRIFLWLFIIVCFLGTIGLFL 499          

Query:  171 TKDARRLYDDLMRRRGYDPSVRPVKSYTSTVLLYMNLSLVQILDVDEKNQIIVLNMWVNQEWNDPNFVWDPNDYGNVTELNIPSREIWTPDLVLYNNAGGDWDLASSSNTKVIVNHDGSVLWKPPIIFKSQCGINVEFFPFDKQLCDLKIGTWTHNGFLIDLRHTAQKNQSQASFDNCNAKIDYAIDLSQYVNNVEWDLLEVSAKRNIEFYPCCTEPYLDISFNVSLRRRTLFYGINLICPCLAISFLTILVFYLPADSGEKXXXXXXXXXXXXXXXXXXXDISPPTSIVVPLILKYLLFTMILVTLSVMATVLVLNIHWRSPDTHKMAPWVRSVFTSTLPKLLFMKKPDQ--DYRDNETDDIPETFHEDETD---------SNIQDKWSTR----------------RAAVSG---DNVVNEIEL--------ALEGVRRIVHHIKKENSYSAMRDDWKYVAVVLDRLFLWLFSIAAIIGMLGIFM 1517
            T+   RL+  L R  GY+   RPV + +  V++   LS+ Q++DVDEKNQ++  N+W+ QEW+D    W+P D+GN+T L +PS  IW PD+VLYNNA G  + A +  TK  +   G+V W PP I+KS C I+V FFPFD+Q C +K G+WT++   IDL    Q                  +DL  Y  + EW ++  +   N + Y CC E Y D+++   +RR  LFY INLI PCL IS LT+LVFYLP+D GEK++L IS+LLSLTVF LLI +I P TS+V+PLI +YLLFTMI VTLS++ TV VLN+H RSP TH M  WVR      +P+ L M +P    +        +  ++H  E++            +D+W+                   +  SG   + ++ E EL        ALEGV  I  H++ E++ S++++DWKYVA+V+DR+FLWLF I   +G +G+F+
Sbjct:   56 TETEDRLFKHLFR--GYNRWARPVPNTSDVVIVRFGLSIAQLIDVDEKNQMMTTNVWLKQEWSDYKLRWNPTDFGNITSLRVPSEMIWIPDIVLYNNADG--EFAVTHMTKAHLFSTGTVHWVPPAIYKSSCSIDVTFFPFDQQNCKMKFGSWTYDKAKIDLEQMEQ-----------------TVDLKDYWESGEWAIVNATGTYNSKKYDCCAEIYPDVTYAFVIRRLPLFYTINLIIPCLLISCLTVLVFYLPSDCGEKITLCISVLLSLTVFLLLITEIIPSTSLVIPLIGEYLLFTMIFVTLSIVITVFVLNVHHRSPSTHTMPHWVRGALLGCVPRWLLMNRPPPPVELCHPLRLKLSPSYHWLESNVDAEEREVVVEEEDRWACAGHVAPSVGTLCSHGHLHSGASGPKAEALLQEGELLLSPHMQKALEGVHYIADHLRSEDADSSVKEDWKYVAMVIDRIFLWLFIIVCFLGTIGLFL 521          

Query:  168 GTKDARRLYDDLMRRRGYDPSVRPVKSYTSTVLLYMNLSLVQILDVDEKNQIIVLNMWVNQEWNDPNFVWDPNDYGNVTELNIPSREIWTPDLVLYNNAGGDWDLASSSNTKVIVNHDGSVLWKPPIIFKSQCGINVEFFPFDKQLCDLKIGTWTHNGFLIDLRHTAQKNQSQASFDNCNAKIDYAIDLSQYVNNVEWDLLEVSAKRNIEFYPCCTEPYLDISFNVSLRRRTLFYGINLICPCLAISFLTILVFYLPADSGEKXXXXXXXXXXXXXXXXXXXDISPPTSIVVPLILKYLLFTMILVTLSVMATVLVLNIHWRSPDTHKMAPWVRSVFTSTLPKLLFMKKPDQDYRDNETDDIP----------------------ETFHEDETDSNIQDKWSTRRAA-------VSGDNVVNEIELALEGVRRIVHHIKKENSYSAMRDDWKYVAVVLDRLFLWLFSIAAIIGMLGIFMQ 1520
            G     RL+  L     Y+  +RPV++ +  V ++  +++ Q+ +VDE NQI+  N+W+   WND    WDP +Y  +  L +P+ +IW PD+VLYNNA GD+ +     TK ++ ++G + W PP IFKS C +++ FFPFD Q C LK G+WT++   IDL     K                 +D++ +  N EW++++ S  ++   Y CC E Y DI+++  +RR  +FY INLI PCL ISFLT+LVFYLP+D GEKV+L IS+LLSLTVF L+I +  P TS+VVPL+ +YLLFTMI VTLS++ TV VLNIH+R+P TH M  WV++VF   LP++L M+ P    R   +D +P                      E FH  +++     K   RR +       V       E+E  +  V+ I  ++K  N    + DDWKYVA+V+DR+FLW+F I  + G  G+F+Q
Sbjct:   30 GCATEERLFHKLFSH--YNQFIRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLRHIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYNNAVGDFQV--EGKTKALLKYNGMITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAEIDLLIIGSK-----------------VDMNDFWENSEWEIIDASGYKHDIKYNCCEEIYTDITYSFYIRRLPMFYTINLIIPCLFISFLTVLVFYLPSDCGEKVTLCISVLLSLTVFLLVITETIPSTSLVVPLVGEYLLFTMIFVTLSIVVTVFVLNIHYRTPTTHTMPRWVKTVFLKLLPQVLLMRWPLDKTRGTGSDAVPRGLARRPAKGKLASHGEPRHLKECFHCHKSNELATSK---RRLSHQPLQWVVENSEHSPEVEDVINSVQFIAENMKSHNETKEVEDDWKYVAMVVDRVFLWVFIIVCVFGTAGLFLQ 485          

Query:  129 CLGFLFGLIFIVQGTKDARRLYDDLMRRRGYDPSVRPVKSYTSTVLLYMNLSLVQILDVDEKNQIIVLNMWVNQEWNDPNFVWDPNDYGNVTELNIPSREIWTPDLVLYNNAGGDWDLASSSNTKVIVNHDGSVLWKPPIIFKSQCGINVEFFPFDKQLCDLKIGTWTHNGFLID-------LRHTAQKNQSQASFDNCNAKIDYAIDLSQYVNNVEWDLLEVSAKRNIEFYP-CCTE-PYLDISFNVSLRRRTLFYGINLICPCLAISFLTILVFYLPADSGEKXXXXXXXXXXXXXXXXXXXDISPPTSIVVPLILKYLLFTMILVTLSVMATVLVLNIHWRSPDTHKMAPWVRSVFTSTLPKLLFMKKPDQDYRD-------NETDDIPETFHEDETDSNIQDKWSTRRAAVSGDNVVNEIEL------ALEGVRRIVHHIKKENSYSAMRDDWKYVAVVLDRLFLWLFSIAAIIGMLGIFMQAPTLTDNAIPMTADNCPSVSSIN 1589
            C+ F    I + +G +DA+RLYDDLM    Y+   RP  S    + + + L L QI+DV E +QI+  ++W+ Q W D    WDP +YG V  L +P   IW PD+VLYNNA  ++++  S  TK  +++ G V W+PP IFKS C I+V +FPFD+Q C LK G+WT +  L+        LR+  + ++ +   DN     D  IDLS Y  +VEWD++   AKR  + YP CC +  Y+D+++ + LRR+ LFY +NL+ PC+ ISFLTILVFYLP+DSGEKV+L ISIL++LT+FFLL+ +I P TSI +PLI KYLLFTM++VTLSV+ TV+ LN+H+R+P TH M  WV+ VF   LPKLLFM++P  DY +        +   I  + H     SN+ +  + R A +  D+ + ++        A E +  I   +KK++    + +DWKYVA+VLDRLFL +FSIA  +G + I ++APTL D   P+     P+  S N
Sbjct:   14 CISF----IKLTEGNEDAKRLYDDLMV--NYNRHRRPSTSPNKPLTIKLKLRLSQIIDVHEIDQIMTCSVWLKQTWIDRKLSWDPVNYGGVNVLYVPYEMIWVPDIVLYNNADSNYNITIS--TKATLHYTGEVTWEPPAIFKSMCQIDVRWFPFDEQQCHLKFGSWTFSENLLSVELNEPSLRYEEEIDE-KGIIDNVTVAED-GIDLSDYYPSVEWDIMSRVAKRRAKNYPSCCPQSAYIDVTYYLQLRRKPLFYTVNLVFPCVGISFLTILVFYLPSDSGEKVTLCISILVALTIFFLLLTEIIPATSITLPLIGKYLLFTMVMVTLSVVVTVISLNLHFRTPTTHLMPNWVKKVFLKWLPKLLFMRRPIDDYEEKFDDKKKPKDGKIALSVHAHRV-SNVGN--NIRNATI--DDTIQKMYYSPPVVKAFENICFIAELLKKKDRDDKIDEDWKYVAMVLDRLFLLIFSIACFVGTVIILLRAPTLYDTRQPIDLQYRPANLSAN 507          

Query:  135 GFLFGLIFIV-----QGTKDARRLYDDLMRRRGYDPSVRPVKSYTSTVLLYMNLSLVQILDVDEKNQIIVLNMWVNQEWNDPNFVWDPNDYGNVTELNIPSREIWTPDLVLYNNAGGDWDLASSSNTKVIVNHDGSVLWKPPIIFKSQCGINVEFFPFDKQLCDLKIGTWTHNGFLIDLRHTAQKNQSQASFDNCNAK---------IDYAIDLSQYVNNVEWDLLEVSAKRNIEFYPCCTEPYLDISFNVSLRRRTLFYGINLICPCLAISFLTILVFYLPADSGEKXXXXXXXXXXXXXXXXXXXDISPPTSIVVPLILKYLLFTMILVTLSVMATVLVLNIHWRSPDTHKMAPWVRSVFTSTLPKLLFMKKPD----QDYRDNETDDIPETF----------HEDETDSNIQDKWSTRRAAVSGDNVVNEIELALEGVRRIVHHIKKENSYSAMRDDWKYVAVVLDRLFLWLFSIAAIIGMLGIFMQAPTLTDNA 1544
            GF + LIF++        +DA RL++DL+    Y+  VRPV     T+++   L L Q+LDV EKNQI+  N+W+   W D    WDP +YG V  L +PS  IW PD+VLYNNA G++ +  +  TK  + ++G+V W PP I+KS C I+VEFFPFD+Q C++K G+WT+ G  +DL+H  +  + +   D              +D  IDLS Y  +VEWD+L V  KR+ + YPCC  P++DI++ + LRR+TLFY +NLI P + ISFLT LVFYLP+D GEK+SL ISIL+SLTVFFLL+ +I P TS+V+PLI KYLLFTM+LVTLSV+ TV+ LN+H+RSP TH M  W++ +F   LPK L M +P         + + D    TF          + +     +          +  DN  + +  A+E V  I  H+K E     + +DWKY++VV+DR+FL  F+ A   G + I  +AP++ DN 
Sbjct:    7 GFAYILIFLLLSPPTHANRDANRLFEDLIA--DYNKLVRPVSENGETLVVTFKLKLSQLLDVHEKNQIMTTNVWLQHSWMDYKLRWDPVEYGGVEVLYVPSDTIWLPDVVLYNNADGNYQV--TIMTKAKLTYNGTVEWAPPAIYKSMCQIDVEFFPFDRQQCEMKFGSWTYGGLEVDLQHRDKHLEKEIEEDVEGVDGPTKEIVWVVDRGIDLSDYYPSVEWDILNVPGKRHSKRYPCCESPFIDITYEIHLRRKTLFYTVNLIFPSVGISFLTALVFYLPSDGGEKISLCISILISLTVFFLLLVEIIPSTSLVIPLIGKYLLFTMVLVTLSVVVTVVTLNVHYRSPTTHTMPKWMKRLFVDFLPKYLLMTRPQPPGHHSKPNRKFDSRASTFSIGVNHVLGQNSELLSPGLNSNREESSFTLPRDN--SPVRSAVESVAYIADHLKNEEDDKQVIEDWKYISVVMDRIFLITFTFACAFGTVVIIARAPSIYDNT 498          

Query:  168 GTKDARRLYDDLMRRRGYDPSVRPVKSYTSTVLLYMNLSLVQILDVDEKNQIIVLNMWVNQEWNDPNFVWDPNDYGNVTELNIPSREIWTPDLVLYNNAGGDWDLASSSNTKVIVNHDGSVLWKPPIIFKSQCGINVEFFPFDKQLCDLKIGTWTHNGFLIDLRHTAQKNQSQASFDNCNAKIDYAIDLSQYVNNVEWDLLEVSAKRNIEFYPCCTEPYLDISFNVSLRRRTLFYGINLICPCLAISFLTILVFYLPADSGEKXXXXXXXXXXXXXXXXXXXDISPPTSIVVPLILKYLLFTMILVTLSVMATVLVLNIHWRSPDTHKMAPWVRSVFTSTLPKLLFMKKPDQDYRDNETDDIPETF------HEDETDSNIQD-KWSTRRA-------------------------------AVSGDNVVNEI--ELALEGVRRIVHHIK-------KENSYSAMRDDWKYVAVVLDRLFLWLFSIAAIIGMLGIFMQAPTL 1532
            G+   RRLY+DLMR   Y+   RPV +++  V +++ ++L QI+DVDEKNQ++ +N W++  WND N VWD  +YGN+T++  P+ +IW PD++LYN+   ++D  S+  T +IV   G V W PP IFK  C I++++FPFD+Q C  K G+WT++G+ +DL+                       D+S+Y++N EW L   + +RN +FY CC EPY D+ F + +RRRTL+YG NLI PC+  + +T+L F LP D+GEK++L I++LLS+  F  ++ ++SPPTS  VPL+  +    MI+VT S + TV VLN+H+R+P+TH M PW R++    +P +L MK+P  +        +P  F      H +    NI+D + S  RA                                +S +    ++  +  L  + RI H +K       + +      ++WK+ A+V+DRL L++F+I  I+  +GIF  AP L
Sbjct:   19 GSLQERRLYEDLMR--NYNNLERPVANHSEPVTVHLKVALQQIIDVDEKNQVVYVNAWLDYTWNDYNLVWDKAEYGNITDVRFPAGKIWKPDVLLYNSVDTNFD--STYQTNMIVYSTGLVHWVPPGIFKISCKIDIQWFPFDEQKCFFKFGSWTYDGYKLDLQPATG-----------------GFDISEYISNGEWALPLTTVERNEKFYDCCPEPYPDVHFYLHMRRRTLYYGFNLIMPCILTTLMTLLGFTLPPDAGEKITLQITVLLSICFFLSIVSEMSPPTSEAVPLLGIFFTCCMIVVTASTVFTVYVLNLHYRTPETHDMGPWTRNLLLYWIPWILRMKRPGHNL---TYASLPSLFSTKPNRHSESLIRNIKDNEHSLSRANSFDADCRLNQYIMTQSVSNGLTSLGSIPSTMISSNGTTTDVSQQATLLILHRIYHELKIVTKRMIEGDKEEQACNNWKFAAMVVDRLCLYVFTIFIIVSTIGIFWSAPYL 496          

Query:  159 IVQGTKDARRLYDDLMRRRGYDPSVRPVKSYTSTVLLYMNLSLVQILDVDEKNQIIVLNMWVNQEWNDPNFVWDPNDYGNVTELNIP--SREIWTPDLVLYNNAGGDWDLASSSNTKVIVNHDGSVLWKPPIIFKSQCGINVEFFPFDKQLCDLKIGTWTHNGFLIDLRHTAQKNQSQASFDNCNAKIDYAIDLSQYVNNVEWDLLEVSAKRNIEFYPCCTEPYLDISFNVSLRRRTLFYGINLICPCLAISFLTILVFYLPADSGEKXXXXXXXXXXXXXXXXXXXDISPPTSIVVPLILKYLLFTMILVTLSVMATVLVLNIHWRSPDTHKMAPWVRSVFTSTLPKLLFMKKPDQDYRD----NETDDIPETFHEDETDSNIQDKWSTRRAAVSGDNVVNEIELALEGVRRIVHHIKKENSYSAMRDDWKYVAVVLDRLFLWLFSIAAIIGMLGIFMQAP 1526
            +  G+    +L+ DL++  GY+P  RPV++ +  + + + L L QILDVDEKNQI+ +N W++  W D    W+P  YG + ++  P  S  IW PD++LYN+A  D+D    SN  ++  H G+V+W PP + K  C ++V +FPFD Q+C++K G+WT +G+ IDL+     N +Q+            +DLS Y+ N EW ++  +AKR + +Y CC EPY  +++ + +RRRTL+YG NLI P L IS + IL F  P D+GEK++L ++ILL++  F  ++ +++PPTS  VPLI  +    M++V+ SV+ T++VLN+H+RS D+H+M P VR V    LP LLFM +P   +      + TD +P+   ++  D N+    +   A +   + V+        +RR+V    KE     ++ DW++ A+V+DR  L LF++  +I +L I M AP
Sbjct:   19 LCDGSVAETKLFTDLLK--GYNPLERPVQNSSQPLEVKIKLFLQQILDVDEKNQIVSVNAWLSYTWFDHKLQWEPKKYGGIQDIRFPGSSDHIWKPDVLLYNSAAEDFDSTFKSN--LLTYHTGTVVWIPPGVLKFVCQLDVTWFPFDDQVCEMKFGSWTFHGYAIDLQIDDDTNGTQS------------MDLSTYLVNGEWQVISTNAKRVVSYYKCCPEPYPTVNYYLHIRRRTLYYGFNLIIPSLLISLMAILGFMFPPDAGEKITLEVTILLAIVFFLSMVSEMTPPTSEAVPLIGVFFSCCMLVVSASVVFTIVVLNLHFRSADSHEMNPLVRRVLLEFLPWLLFMSRPGYKFVKANVIDSTDKMPKK-PKNPLDCNLPSNHAGYEAQILLLHSVH------TELRRVVAFYNKEEHDERIQTDWRFAAMVVDRACLLLFTVFIVISILAIMMSAP 457          

Query:  147 GLIFIVQGTKDARRLYDDLMRRRGYDPSVRPVKSYTSTVLLYMNLSLVQILDVDEKNQIIVLNMWVNQEWNDPNFVWDPNDYGNVTELNIPSREIWTPDLVLYNNAGGDWDLASSSNTKVIVNHDGSVLWKPPIIFKSQCGINVEFFPFDKQLCDLKIGTWTHNGFLIDLRHTAQKNQSQASFDNCNAKIDYAIDLSQYVNNVEWDLLEVSAKRNIEFYP-CCTEP-YLDISFNVSLRRRTLFYGINLICPCLAISFLTILVFYLPADSGEKXXXXXXXXXXXXXXXXXXXDISPPTSIVVPLILKYLLFTMILVTLSVMATVLVLNIHWRSPDTHKMAPWVRSVFTSTLPKLLFMKKPDQD---YRDNETDDI--------PETFHEDETDSNIQDKWST-RRAAVSGDNVVNEIELALEGVRRIVHHIKKENSYSAMRDDWKYVAVVLDRLFLWLFSIAAIIGMLGIFMQAPTLTDNAIPM 1553
            GL F V   + A ++Y+DL+    Y+ +VRP+K+ + +V +    SL++I+DVDE NQ++  N+W+  +W D   +WDP  +G + +L++P  +IW PD++LYNNA G+  +   S+   IV ++G V+WKPP I+KS C I++E+FP+D Q C +K G WT+NGFL+D+R    +  +            +A  +S +  ++EWDL+E+++ R+ + Y  CC +  Y+DI+F + +RR+TLFY INL+ PC   + LT +VFY+P     K++ SISIL++LTVF+L++ D+ PPTS+V+PLI KYLLFTM LV++S+M +V+ LN + R   +  M  W++ VF  TLP+ + +K  ++D    R +   DI        P  F     +  +  + S  ++  +  D + N I+  +E +    + +KKE+  S   +DW YVA V+DR+FL +FSI  ++G   I + +P L DN  P+
Sbjct:   14 GLFFYVNPNRYADQMYEDLLYY--YNKNVRPIKNASESVKVKFGSSLIRIIDVDEVNQVLTTNLWLEMQWFDYRLMWDPGRWGKIRKLHVPVDQIWIPDILLYNNADGEPHITIMSDA--IVYYNGLVVWKPPSIYKSFCSIDIEYFPYDTQTCWMKFGGWTYNGFLLDVRQLPVEEWTLVVTTRKLQVCAHASSISFFFRSLEWDLMELNSARHEKIYAGCCGQDFYIDITFKIEIRRKTLFYTINLMIPCTMFAILTSIVFYVPPIE-HKMTFSISILVTLTVFYLILIDLVPPTSLVIPLIGKYLLFTMFLVSISIMLSVISLNFYRRDGSSFPMPHWMKVVFIHTLPRYICIKTAEEDDGSDRGSSISDIGPFMDSRRPSPFFITVNERQLNGRLSELKKKGMHPDLIRNMIQ-NVEFIAEYFNSLKKEDKVS---EDWSYVANVIDRIFLIIFSIMNVVGTWVILLNSPALFDNRTPL 487          

Query:  162 VQGTKDARRLYDDLMRRRGYDPSVRPVKSYTSTVLLYMNLSLVQILDVDEKNQIIVLNMWVNQEWNDPNFVWDPNDYGNVTELNIPSREIWTPDLVLYNNAGGDWDLASSSNTKVIVNHDGSVLWKPPIIFKSQCGINVEFFPFDKQLCDLKIGTWTHNGFLIDLRHTAQKNQSQASFDNCNAKIDYAIDLSQYVNNVEWDLLEVSAKRNIEFYPCCTEPYLDISFNVSLRRRTLFYGINLICPCLAISFLTILVFYLPADSGEKXXXXXXXXXXXXXXXXXXXDISPPTSIVVPLILKYLLFTMILVTLSVMATVLVLNIHWRSPDTHKMAPWVRSVFTSTLPKLLFMKKPDQDYRDNETDD------------IPETFH--EDET----DSNI----QDKWSTRRAAVSGDNVVNEIELALEGVRRIVHHIKKENSYSAMRDDWKYVAVVLDRLFLWLFSIAAIIGMLGIFMQAPTLTDNAIPM 1553
            V G  DA+RLYDDL+    Y+  VRPV + T  + + + L L Q++DV+ KNQI+  N+WV Q W D    W+P +YG V  L++PS  IW PD+VLYNNA G++++  +  TK  +  +G V WKPP I+KS C I+VE+FPFD+Q C LK G+WT++GF +DLRH  ++  S          +   +DLS++  +VEWD+LEV A RN +FY CC EPYLDI+FN+++RR+TLFY +N+I PC+ ISFLT+L FYLP+DSGEKV+LSISIL+SL VFFLL+ +I PPTS+VVPL+ KYL+F MILV++S+  TV+VLN+H+RSP THKMAPWV+ VF   LP  LF+K+P  ++  + T +            +P   H   DE     D +I             A S    + +I  +   VR I  H K +   + +++DWKYVA+VLDRLFLW+F++A ++G  GI +QAPTL D+ IP+
Sbjct:    6 VAGNPDAKRLYDDLLS--NYNKLVRPVVNTTDVLKVCIKLKLSQLIDVNLKNQIMTTNLWVEQSWYDYKLRWEPKEYGGVHMLHVPSDHIWRPDIVLYNNADGNFEVTLA--TKATIYSEGLVEWKPPAIYKSSCEIDVEYFPFDEQTCVLKFGSWTYDGFKVDLRHMDEQQGSNV--------VAVGVDLSEFYMSVEWDILEVPAVRNEKFYTCCDEPYLDITFNITMRRKTLFYTVNIIIPCMGISFLTVLTFYLPSDSGEKVTLSISILISLHVFFLLVVEIIPPTSLVVPLLGKYLIFAMILVSISICVTVVVLNVHFRSPQTHKMAPWVKRVFIDFLPAFLFIKRPTYNFETSITANGPFGGSCQVHGPVPPLTHCSSDEIAAVPDMDIGPLGMKSPILNNPAFSHSKCLPKIHKSCFCVRFIAEHTKMQEDSTKVKEDWKYVAMVLDRLFLWIFTLAVVVGTAGIILQAPTLYDDRIPI 479          

Query:  165 QGTKDARRLYDDLMRRRGYDPSVRPVKSYTSTVLLYMNLSLVQILDVDEKNQIIVLNMWVNQEWNDPNFVWDPNDYGNVTELNIPSREIWTPDLVLYNNAGGDWDLASSSNTKVIVNHDGSVLWKPPIIFKSQCGINVEFFPFDKQLCDLKIGTWTHNGFLIDLRHTAQKNQSQASFDNCNAKIDYAIDLSQYVNNVEWDLLEVSAKRNIEFYPCCTEPYLDISFNVSLRRRTLFYGINLICPCLAISFLTILVFYLPADSGEKXXXXXXXXXXXXXXXXXXXDISPPTSIVVPLILKYLLFTMILVTLSVMATVLVLNIHWRSPDTHKMAPWVRSVFTSTLPKLLFMKKPD---QDYRD--------NETD------DIPETFHEDE---TDSNIQDKWSTRRAAVSGDNVVNEIELALEGVRRIVHHIKKENSYSAMRDDWKYVAVVLDRLFLWLFSIAAIIGMLGIFMQAPTLTDNAIPM 1553
            +   D +RLYDDL+    Y+  +RPV + T T+ +++ L L Q+++V+ KNQ++  N+WV Q W D    WDP +YG V +L +PS  IW PD+VLYNN  G++++  +  TK  + + G V W+PP I+KS C +NVE+FP+D+Q+C +K G+WT+NG  +DL+H  Q   S          +   IDL+++  +VEWD+LEV A +N E+YP   EP+ DI+F +++RR+TLFY +NLI PC+A++FLT+LVFYLP+DSGEKV+L ISIL+SLTVFFLL+ +I PPTS+ VPL+ KYLLFTMILV+LSV  TV VLNIH+RSP TH M+P VR +F   +PKL+ M++      DY D        NE D      D P  F + +    D+ +Q+  S     V   N+  E+  AL  VR I  HIK  +  + + +DWK+V++VLDR FLWLF+++ + G L I  Q+P+L D   P+
Sbjct:   25 EANPDTKRLYDDLLS--NYNRLIRPVVNNTETLTVWLGLKLSQLIEVNLKNQVMTTNLWVKQRWFDYKLRWDPEEYGGVEQLYVPSEHIWVPDIVLYNNWDGNYEV--TLMTKATLKYTGEVFWEPPAIYKSSCEMNVEYFPYDEQICFMKFGSWTYNGAQVDLKHLDQIPGSNL--------VQVGIDLTEFYLSVEWDILEVPATKNEEYYPDTLEPFSDITFKLTMRRKTLFYTVNLIVPCVALTFLTVLVFYLPSDSGEKVTLCISILVSLTVFFLLLAEIIPPTSLAVPLLGKYLLFTMILVSLSVWTTVCVLNIHFRSPSTHNMSPLVRKLFLHFMPKLMMMRRTQYTLPDYDDSTPSNGYTNEIDVRDSISDFPSEFKDSQDGAYDNGMQN--SVDSDNVIPRNLTPEVLQALRAVRFIAQHIKDADKDNEIVEDWKFVSMVLDRFFLWLFTLSCVFGTLAIICQSPSLYDTRSPI 493          

Query:  162 VQGTKDARRLYDDLMRRRGYDPSVRPVKSYTSTVLLYMNLSLVQILDVDEKNQIIVLNMWVNQEWNDPNFVWDPNDYGNVTELNIPSREIWTPDLVLYNNAGGDWDLASSSNTKVIVNHDGSVLWKPPIIFKSQCGINVEFFPFDKQLCDLKIGTWTHNGFLIDLRHTAQKNQSQASFDNCNAKIDYAIDLSQYVNNVEWDLLEVSAKRNIEFYPCCTEPYLDISFNVSLRRRTLFYGINLICPCLAISFLTILVFYLPADSGEKXXXXXXXXXXXXXXXXXXXDISPPTSIVVPLILKYLLFTMILVTLSVMATVLVLNIHWRSPDTHKMAPWVRSVFTSTLPKLLFMKKPDQDYRDNETDDI 1253
            VQ   DA+RLYDDL+    Y+  +RPV + T TVL+ + L L Q++D++ K+QI+  N+W+  EW D  F WDP++YG VTEL +PS  IW PD+VLYNNA G++    ++ TK I+++ G V+W PP IFKS C I+V +FPFD+Q C +K G+WT++G  IDL+H +QKN      DN   K++  IDL +Y  +VEWD+L V A+R+ ++YPCC EPY DI FN++LRR+TLFY +NLI PC+ IS+L++LVFYLPADSGEK++L ISILLS T+FFLLI +I P TS+ +PL+ KYLLFTM+LV LSV+ T+++LNIH+R P THKM PW+RS F   LPKLL M+ P    RD   + I
Sbjct:   39 VQANPDAKRLYDDLLS--NYNRLIRPVSNNTDTVLVKLGLRLSQLIDLNLKDQILTTNVWLEHEWQDHKFKWDPSEYGGVTELYVPSEHIWLPDIVLYNNADGEY--VVTTMTKAILHYTGKVVWTPPAIFKSSCEIDVRYFPFDQQTCFMKFGSWTYDGDQIDLKHISQKNDK----DN---KVEIGIDLREYYPSVEWDILGVPAERHEKYYPCCAEPYPDIFFNITLRRKTLFYTVNLIIPCVGISYLSVLVFYLPADSGEKIALCISILLSQTMFFLLISEIIPSTSLALPLLGKYLLFTMLLVGLSVVITIIILNIHYRKPSTHKMRPWIRSFFIKRLPKLLLMRVPKDLLRDLAANKI 391          

Query: 1347 EIELALEGVRRIVHHIKKENSYSAMRDDWKYVAVVLDRLFLWLFSIAAIIGMLGIFMQAPTLTDNA 1544
            E+E A+  V  I HH+++++ ++A   DW +VA+V+DRLFLWLF IA+++G   I  +AP+L D+ 
Sbjct:  489 ELEKAIHNVMFIQHHMQRQDEFNAEDQDWGFVAMVMDRLFLWLFMIASLVGTFVILGEAPSLYDDT 554          

Query:  162 VQGTKDARRLYDDLMRRRGYDPSVRPVKSYTSTVLLYMNLSLVQILDVDEKNQIIVLNMWVNQEWNDPNFVWDPNDYGNVTELNIPSREIWTPDLVLYNNAGGDWDLASSSNTKVIVNHDGSVLWKPPIIFKSQCGINVEFFPFDKQLCDLKIGTWTHNGFLIDLRHTAQKNQSQASFDNCNAKIDYAIDLSQYVNNVEWDLLEVSAKRNIEFYPCCTEPYLDISFNVSLRRRTLFYGINLICPCLAISFLTILVFYLPADSGEKXXXXXXXXXXXXXXXXXXXDISPPTSIVVPLILKYLLFTMILVTLSVMATVLVLNIHWRSPDTHKMAPWVRSVFTSTLPKLLFMKKPDQDYRDNETDDI 1253
            VQ   DA+RLYDDL+    Y+  +RPV + T TVL+ + L L Q++D++ K+QI+  N+W+  EW D  F WDP++YG VTEL +PS  IW PD+VLYNNA G++    ++ TK I+++ G V+W PP IFKS C I+V +FPFD+Q C +K G+WT++G  IDL+H +QKN      DN   K++  IDL +Y  +VEWD+L V A+R+ ++YPCC EPY DI FN++LRR+TLFY +NLI PC+ IS+L++LVFYLPADSGEK++L ISILLS T+FFLLI +I P TS+ +PL+ KYLLFTM+LV LSV+ T+++LNIH+R P THKM PW+RS F   LPKLL M+ P    RD   + I
Sbjct:   39 VQANPDAKRLYDDLLS--NYNRLIRPVSNNTDTVLVKLGLRLSQLIDLNLKDQILTTNVWLEHEWQDHKFKWDPSEYGGVTELYVPSEHIWLPDIVLYNNADGEY--VVTTMTKAILHYTGKVVWTPPAIFKSSCEIDVRYFPFDQQTCFMKFGSWTYDGDQIDLKHISQKNDK----DN---KVEIGIDLREYYPSVEWDILGVPAERHEKYYPCCAEPYPDIFFNITLRRKTLFYTVNLIIPCVGISYLSVLVFYLPADSGEKIALCISILLSQTMFFLLISEIIPSTSLALPLLGKYLLFTMLLVGLSVVITIIILNIHYRKPSTHKMRPWIRSFFIKRLPKLLLMRVPKDLLRDLAANKI 391          

Query: 1347 EIELALEGVRRIVHHIKKENSYSAMRDDWKYVAVVLDRLFLWLFSIAAIIGMLGIFMQAPTLTDNA 1544
            E+E A+  V  I HH+++++ ++A   DW +VA+V+DRLFLWLF IA+++G   I  +AP+L D+ 
Sbjct:  489 ELEKAIHNVMFIQHHMQRQDEFNAEDQDWGFVAMVMDRLFLWLFMIASLVGTFVILGEAPSLYDDT 554          

Query:  162 VQGTKDARRLYDDLMRRRGYDPSVRPVKSYTSTVLLYMNLSLVQILDVDEKNQIIVLNMWVNQEWNDPNFVWDPNDYGNVTELNIPSREIWTPDLVLYNNAGGDWDLASSSNTKVIVNHDGSVLWKPPIIFKSQCGINVEFFPFDKQLCDLKIGTWTHNGFLIDLRHTAQKNQSQASFDNCNAKIDYAIDLSQYVNNVEWDLLEVSAKRNIEFYPCCTEPYLDISFNVSLRRRTLFYGINLICPCLAISFLTILVFYLPADSGEKXXXXXXXXXXXXXXXXXXXDISPPTSIVVPLILKYLLFTMILVTLSVMATVLVLNIHWRSPDTHKMAPWVRSVFTSTLPKLLFMKKPDQDYRDNE--TDDIPETFHEDETDSNI 1292
            V G  DA+RLYDDL+    Y+  VRPV + T  + + + L L Q++DV+ KNQI+  N+WV Q W D    W+P +YG V  L++PS  IW PD+VLYNNA G +++  +  TK IV ++G V+W+PP ++KS C I+VE+FP+D Q C LK+G+WT++GF +DLRH  ++  S          +   +DLS++  +VEWD+LEV A RN +FY CC EPYLDI+FN+++RR+TLFY +N+I PC+ ISFLT+L FYLP+DSGEKV+LSISIL+SL VFFLL+ +I PPTS+VVPL+ KYL+F MILV++S+  TV+VLN+H+RSP THKMAPWV+ VF   LP  LF+K+P  ++  ++    D    F+   + +NI
Sbjct:    6 VAGNPDAKRLYDDLLS--NYNKLVRPVVNTTDVLKVCIKLKLSQLIDVNLKNQIMTTNLWVEQSWYDYKLRWEPKEYGGVHMLHVPSDHIWRPDIVLYNNADGHYEV--TLMTKAIVYNNGLVIWQPPAVYKSSCSIDVEYFPYDVQTCILKLGSWTYDGFKVDLRHMDEQQGSNV--------VAVGVDLSEFYMSVEWDILEVPAVRNEKFYTCCDEPYLDITFNITMRRKTLFYTVNIIIPCMGISFLTVLTFYLPSDSGEKVTLSISILISLHVFFLLVVEIIPPTSLVVPLLGKYLIFAMILVSISICVTVVVLNVHFRSPQTHKMAPWVKRVFIDFLPAFLFIKRPTYNFETSKLLLKDTHACFYPYYSATNI 372          

Query: 1320 AVSGDNVVNEIELALEGVRRIVHHIKKENSYSAMRDDWKYVAVVLDRLFLWLFSIAAIIGMLGIFMQAPTLTDNAIPM 1553
            A S    + +I  +   VR I  H K +   + +++DWKYVA+VLDRLFLW+F++A ++G  GI +QAPTL D+ IP+
Sbjct:  442 AFSHSKCLPKIHKSCFCVRFIAEHTKMQEDSTKVKEDWKYVAMVLDRLFLWIFTLAVVVGTAGIILQAPTLYDDRIPI 519          

Query:  216 GYDPSVRPVKSYTSTVLLYMNLSLVQILDVDEKNQIIVLNMWVNQEWNDPNFVWDPNDYGNVTELNIPSREIWTPDLVLYNNAGGDWDLASSSNTKVIVNHDGSVLWKPPIIFKSQCGINVEFFPFDKQLCDLKIGTWTHNGFLIDLRHTAQKNQSQASFDNCNAKIDYAIDLSQYVNNVEWDLLEVSAKRNIEFYPCCTEPYLDISFNVSLRRRTLFYGINLICPCLAISFLTILVFYLPADSGEKXXXXXXXXXXXXXXXXXXXDISPPTSIVVPLILKYLLFTMILVTLSVMATVLVLNIHWRSPDTHKMAPWVRSVFTSTLPKLLFMKKPDQDYRDNETDDI--PETFHEDET--------DSNIQDKWSTRRAAVSG---------------------------------DNVVNEIEL--------ALEGVRRIVHHIKKENSYSAMRDDWKYVAVVLDRLFLWLFSIAAIIGMLGIFM 1517
            GY+   RPV++ +  V++   LS+ Q++DVDEKNQ++  N+W+ QEWND    W+P+++ NVT + +PS  IW PD+VLYNNA G  + A +  TK  + H G V W PP I+KS C I+V FFPFD+Q C +K G+WT++   IDL                  +I+  +DL  Y  + EW ++      N + Y CC E Y DI++   +RR  LFY INLI PCL IS LT+LVFYLP+D GEK++L IS+LLSLTVF LLI +I P TS+V+PLI +YLLFTMI VTLS++ TV VLN+H RSP TH M  WV SVF   +P+ LFM++P+ + +  +T ++   +++ + ET        D       ST  ++ S                                   N+V+E  L        ALEGVR I  H++ E+   ++++DWKYVA+V+DR+FLW+F I  ++G +G+F+
Sbjct:   47 GYNKWSRPVRNISDVVIVKFGLSIAQLIDVDEKNQMMTTNVWLKQEWNDYKLRWNPSEFDNVTSIRVPSEMIWVPDIVLYNNADG--EFAVTHMTKAHLFHTGKVSWVPPAIYKSSCSIDVTFFPFDQQNCKMKFGSWTYDKAKIDLE-----------------QIEGTVDLKDYWESGEWAIINAVGTYNTKKYDCCHEIYPDITYFFIIRRLPLFYTINLIIPCLLISCLTVLVFYLPSDCGEKITLCISVLLSLTVFLLLITEIIPSTSLVIPLIGEYLLFTMIFVTLSIVITVFVLNVHHRSPSTHSMPRWVHSVFLDHIPRWLFMRRPEPEKKPKKTANLSTSKSWFQQETGVDGLVCQDMEFGIGLSTSISSPSATSLHLSDSEPLLQKYELQHLGHVVNLCQHPAKLGNLVSEPGLLFSPCVLRALEGVRYIADHLRAEDEDFSVKEDWKYVAMVIDRIFLWMFIIVCLLGTIGLFL 512          

Query:  147 GLIFIVQGTKDA---RRLYDDLMRRRGYDPSVRPVKSYTSTVLLYMNLSLVQILDVDEKNQIIVLNMWVNQEWNDPNFVWDPNDYGNVTELNIPSREIWTPDLVLYNNAGGDWDLASSSNTKVIVNHDGSVLWKPPIIFKSQCGINVEFFPFDKQLCDLKIGTWTHNGFLIDLRHTAQKNQSQASFDNCNAKIDYAIDLSQYVNNVEWDLLEVSAKRNIEFYPCCTEP-YLDISFNVSLRRRTLFYGINLICPCLAISFLTILVFYLPADSGEKXXXXXXXXXXXXXXXXXXXDISPPTSIVVPLILKYLLFTMILVTLSVMATVLVLNIHWRSPDTHKMAPWVRSVFTSTLPKLLFMKKPDQD----------YRDNETDDIP------ETFHEDETDSNIQDKWST----------RRAAVSGDNVVNEIELALEGVRRIVHHIKKENSYSAMRDDWKYVAVVLDRLFLWLFSIAAIIGMLGIFMQAPTLT 1535
            GL   V G+  A    RL D L+    Y+  +RP  + +  V + + +SL Q++ V+E+ QI+  N+W+ QEWND   VWDPN+Y  + +L IPSR IW PD+VLYNNA G ++++   N   +V++ G + W PP I+KS C I V  FPFD+Q C LK  +WT++   +DL  T+                D+A     Y  + EWD++ +  +RN +     ++P YLD++++  ++R+ LFY INLI PC+ I+ L ILVFYLP+D GEK++L IS+LL+LTVF LLI  I PPTS+ VPLI KYL+FTM+LVT S++ +V VLN+H RSP TH+M  WV+ VF   LP  L M++P +            R + + D        +++   +    +   W            +R  V  D  V+E   A+EGVR I  H+K E+    + +DWKYVA+V+DRLFLW+F +  ++G LG+F+Q   L+
Sbjct:    2 GLRLEVIGSLAADAEERLVDFLLGPERYNKLIRPAVNKSQQVTIGIKVSLAQLISVNEREQIMTTNVWLTQEWNDYRLVWDPNEYEGIKKLRIPSRHIWLPDIVLYNNADGVYEVSFYCNA--VVSNTGDIFWLPPAIYKSACAIEVRNFPFDQQNCTLKFRSWTYDRTELDLYLTS----------------DFA-SRDDYTPSGEWDIVSLPGRRNEDL----SDPTYLDVTYDFVIKRKPLFYTINLIIPCVLITSLAILVFYLPSDCGEKMTLCISVLLALTVFLLLISKIVPPTSLAVPLIGKYLMFTMVLVTFSIVTSVCVLNVHHRSPSTHRMPEWVKRVFLHKLPFFLLMRRPGRSNVRERFRRKHQRKSFSSDTKGLRLDGDSYFLSDDPGRVCGAWRVGDLPEGSEFRQRVKVRHDPDVDE---AIEGVRFIAEHMKIEDDDEGIIEDWKYVAMVIDRLFLWIFILVCVVGTLGLFVQPHALS 468          

Query:  150 LIFIVQG---TKDARRLYDDLMRRRGYDPSVRPVKSYTSTVLLYMNLSLVQILDVDEKNQIIVLNMWVNQEWNDPNFVWDPNDYGNVTELNIPSREIWTPDLVLYNNAGGDWDLASSSNTKVIVNHDGSVLWKPPIIFKSQCGINVEFFPFDKQLCDLKIGTWTHNGFLIDLRHTAQKNQSQASFDNCNAKIDYAIDLSQYVNNVEWDLLEVSAKRNIEFYPCCTEPYLDISFNVSLRRRTLFYGINLICPCLAISFLTILVFYLPADSGEKXXXXXXXXXXXXXXXXXXXDISPPTSIVVPLILKYLLFTMILVTLSVMATVLVLNIHWRSPDTHKMAPWVRSVFTSTLPKLLFMKKPDQDY---------------------RDNETDDIPETFHE-------------------DETDSNIQDKWSTRRAAVSGDN------VVNEIELALEGVRRIVHHIKKENSYSAMRDDWKYVAVVLDRLFLWLFSIAAIIGMLGIFMQAPTLTDN 1541
            L F++ G   ++   RL+  +     Y+  +RPV++ +  V++   +S+ Q++ VDE NQI+  N+W+   WND    WDP D+G V  + +PS +IW PD+VLYNNA GD+ +     TK ++  +G V W PP IFKS C I+V +FPFD Q C +K G+WT++   IDL                   I   I+L  +  + EW +++    ++   Y CC E Y DI++++ +RR  LFY IN+I PCL ISFLT+LVFYLP+D GEKV+L IS+LLSLTVF L+I +  P TS+V+PLI +YLLFTMI VTLS++ TV VLN+H+R+P TH M  WVR VF S LP+++FM +P++D                      R  +    P   +E                   + T    +D  S   ++ S D       V  ++  A+E V+ I  +++ +N    ++DDWKYVA+V+DR+FLW+F +  I+G  G+F+Q   L ++
Sbjct:   51 LCFLLSGVCCSEAEHRLFSVIFS--SYNQYIRPVENVSDPVVVQFEVSMSQLVKVDEVNQIMETNLWLRHIWNDYKLRWDPKDFGGVEFIRVPSNKIWKPDIVLYNNAVGDFQV--DDKTKALLRFNGDVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWTYDKAKIDL-----------------VLIGSTINLKDFWESGEWTIIDAPGYKHDIKYNCCEEIYTDITYSLYIRRLPLFYTINMIIPCLLISFLTVLVFYLPSDCGEKVTLCISVLLSLTVFLLVITETIPSTSLVIPLIGEYLLFTMIFVTLSIVITVFVLNVHYRTPKTHTMPCWVRRVFLSLLPRVMFMTRPEKDQEVPAKQCSVHPPVSSKQTSVCRGPQLLLCPTELNEASRTAFLCREHHCWKKHISNMTSEGAEDGGSPCSSSESLDGFLCMSAVSPQVREAIESVKYIAENMRLQNEAKEVQDDWKYVAMVIDRIFLWVFVLVCILGTAGLFLQPLLLGED 542          

Query:  126 ICLGFLFGLIFIVQGTKDAR-RLYDDLMRRRGYDPSVRPVKSYTSTVLLYMNLSLVQILDVDEKNQIIVLNMWVNQEWNDPNFVWDPNDYGNVTELNIPSREIWTPDLVLYNNAGGDWDLASSSNTKVIVNHDGSVLWKPPIIFKSQCGINVEFFPFDKQLCDLKIGTWTHNGFLIDLRHTAQKNQSQASFDNCNAKIDYAIDLSQYVNNVEWDLLEVSAKRNIEFYPCCTEP-YLDISFNVSLRRRTLFYGINLICPCLAISFLTILVFYLPADSGEKXXXXXXXXXXXXXXXXXXXDISPPTSIVVPLILKYLLFTMILVTLSVMATVLVLNIHWRSPDTHKMAPWVRSVFTSTLPKLLFMKKPDQD----------YRDNETDDIP------ETFHEDETDSNIQDKWST----------RRAAVSGDNVVNEIELALEGVRRIVHHIKKENSYSAMRDDWKYVAVVLDRLFLWLFSIAAIIGMLGIFMQ 1520
            +C+     +  +     DA  RL D L+    Y+  +RP  + +  V + + +SL Q++ V+E+ QI+  N+W+ QEWND   VWDPN+Y  + +L IPSR IW PD+VLYNNA G ++++   N   +V++ G + W PP I+KS C I V  FPFD+Q C LK  +WT++   +DL  T+                D+A     Y  + EWD++ +  +RN +     ++P YLD++++  ++R+ LFY INLI PC+ I+ L ILVFYLP+D GEK++L IS+LL+LTVF LLI  I PPTS+ VPLI KYL+FTM+LVT S++ +V VLN+H RSP TH+M  WV+ VF   LP  L M++P +            R + + D        +++   +    +   W            +R  V  D  V+E   A+EGVR I  H+K E+    + +DWKYVA+V+DRLFLW+F +  ++G LG+F+Q
Sbjct:   11 VCICVCMYVCVLGSLAADAEERLVDFLLGPERYNKLIRPAVNKSQQVTIGIKVSLAQLISVNEREQIMTTNVWLTQEWNDYRLVWDPNEYEGIKKLRIPSRHIWLPDIVLYNNADGVYEVSFYCNA--VVSNTGDIFWLPPAIYKSACAIEVRNFPFDQQNCTLKFRSWTYDRTELDLYLTS----------------DFA-SRDDYTPSGEWDIVSLPGRRNEDL----SDPTYLDVTYDFVIKRKPLFYTINLIIPCVLITSLAILVFYLPSDCGEKMTLCISVLLALTVFLLLISKIVPPTSLAVPLIGKYLMFTMVLVTFSIVTSVCVLNVHHRSPSTHRMPEWVKRVFLHKLPFFLLMRRPGRSNVRERFRRKHQRKSFSSDTKGLRLDGDSYFLSDDPGRVCGAWRVGDLPEGSEFRQRVKVRHDPDVDE---AIEGVRFIAEHMKIEDDDEGIIEDWKYVAMVIDRLFLWIFILVCVVGTLGLFVQ 477          

Query:  141 LFGLIFIVQGTKDA---RRLYDDLMRRRGYDPSVRPVKSYTSTVLLYMNLSLVQILDVDEKNQIIVLNMWVNQEWNDPNFVWDPNDYGNVTELNIPSREIWTPDLVLYNNAGGDWDLASSSNTKVIVNHDGSVLWKPPIIFKSQCGINVEFFPFDKQLCDLKIGTWTHNGFLIDLRHTAQKNQSQASFDNCNAKIDYAIDLSQYVNNVEWDLLEVSAKRNIEFYPCCTEP-YLDISFNVSLRRRTLFYGINLICPCLAISFLTILVFYLPADSGEKXXXXXXXXXXXXXXXXXXXDISPPTSIVVPLILKYLLFTMILVTLSVMATVLVLNIHWRSPDTHKMAPWVRSVFTSTLPKLLFMKKPDQD----------YRDNETDDIP------ETFHEDETDSNIQDKWST----------RRAAVSGDNVVNEIELALEGVRRIVHHIKKENSYSAMRDDWKYVAVVLDRLFLWLFSIAAIIGMLGIFMQ 1520
            L  L FI + +  A    RL D L+    Y+  +RP  + +  V + + +SL Q++ V+E+ QI+  N+W+ QEWND   VWDPN+Y  + +L IPSR IW PD+VLYNNA G ++++   N   +V++ G + W PP I+KS C I V  FPFD+Q C LK  +WT++   +DL  T+                D+A     Y  + EWD++ +  +RN +     ++P YLD++++  ++R+ LFY INLI PC+ I+ L ILVFYLP+D GEK++L IS+LL+LTVF LLI  I PPTS+ VPLI KYL+FTM+LVT S++ +V VLN+H RSP TH+M  WV+ VF   LP  L M++P +            R + + D        +++   +    +   W            +R  V  D  V+E   A+EGVR I  H+K E+    + +DWKYVA+V+DRLFLW+F +  ++G LG+F+Q
Sbjct:    5 LIKLCFIARWSLAADAEERLVDFLLGPERYNKLIRPAVNKSQQVTIGIKVSLAQLISVNEREQIMTTNVWLTQEWNDYRLVWDPNEYEGIKKLRIPSRHIWLPDIVLYNNADGVYEVSFYCNA--VVSNTGDIFWLPPAIYKSACAIEVRNFPFDQQNCTLKFRSWTYDRTELDLYLTS----------------DFA-SRDDYTPSGEWDIVSLPGRRNEDL----SDPTYLDVTYDFVIKRKPLFYTINLIIPCVLITSLAILVFYLPSDCGEKMTLCISVLLALTVFLLLISKIVPPTSLAVPLIGKYLMFTMVLVTFSIVTSVCVLNVHHRSPSTHRMPEWVKRVFLHKLPFFLLMRRPGRSNVRERFRRKHQRKSFSSDTKGLRLDGDSYFLSDDPGRVCGAWRVGDLPEGSEFRQRVKVRHDPDVDE---AIEGVRFIAEHMKIEDDDEGIIEDWKYVAMVIDRLFLWIFILVCVVGTLGLFVQ 468          

Query:  117 FTMICLGFLFGLIFIVQGTKD--ARRLYDDLMRRRGYDPSVRPVKSYTSTVLLYMNLSLVQILDVDEKNQIIVLNMWVNQEWNDPNFVWDPNDYGNVTELNIPSREIWTPDLVLYNNAGGDWDLASSSNTKVIVNHDGSVLWKPPIIFKSQCGINVEFFPFDKQLCDLKIGTWTHNGFLIDLRHTAQKNQSQASFDNCNAKIDYAIDLSQYVNNVEWDLLEVSAKRNIEFYPCCTEPYLDISFNVSLRRRTLFYGINLICPCLAISFLTILVFYLPADSGEKXXXXXXXXXXXXXXXXXXXDISPPTSIVVPLILKYLLFTMILVTLSVMATVLVLNIHWRSPDTHKMAPWVRSVFTSTLPKLLFMKKPDQDYRDNETD-DIPE---TFHEDETDSNIQDKWSTRRAAVSGDNVVN------------------------------------------EIELALEGVRRIVHHIKKENSYSAMRDDWKYVAVVLDRLFLWLFSIAAIIGMLGIFM 1517
             +++C    F  +  ++ T+     RL+  L    GY+   RPV + +  V++   LS+ Q++DVDEKNQ++  N+W+ QEWND    W+P DY NVT + +PS  IW PD+VLYNNA G  + A +  TK  + H+G V W PP I+KS C I+V FFPFD+Q C +K G+WT++   +DL  + ++N                +DL  Y  + EW ++    K N + Y CCTE Y DI++   +RR  LFY INLI PCL IS LT+LVFYLP+D GEK++L IS+LLSLTVF LLI +I P TS+V+PLI +YLLFTMI VTLS++ TV VLN+H RSP THKM  WVRSVF   +P+ LFMK+P     +  +  D PE   +  +   ++++ DKW+   A +   +V +                                           +  ALEGV  I +H++ E++  ++++DWKYVA+V+DR+FLW+F I  ++G +G+F+
Sbjct:    9 LSILCWIITFTTVSCMERTRTHAEERLFKRLFT--GYNRWSRPVPNTSDVVIVKFGLSIAQLIDVDEKNQMMTTNVWLKQEWNDYKLRWNPADYDNVTSIRVPSEMIWIPDIVLYNNADG--EFAITHMTKAHLFHNGKVKWVPPAIYKSSCSIDVTFFPFDQQSCKMKFGSWTYDKAWLDLE-SMERN----------------VDLKDYWESGEWAIVNAVGKYNSKKYDCCTEIYPDITYYFIIRRLPLFYTINLIIPCLLISCLTVLVFYLPSDCGEKITLCISVLLSLTVFLLLITEIIPSTSLVIPLIGEYLLFTMIFVTLSIVITVFVLNVHHRSPSTHKMPLWVRSVFLDHIPRWLFMKRPPAPVEEVVSQYDAPELKLSTSKYWMETDVDDKWAEPEAELQTCHVRHMTTHNQSLQYRYDYNHHVSGGQSQTPRHSSTETAESSFLLSPSVLKALEGVHYIANHLRAEDADFSVKEDWKYVAMVIDRIFLWMFIIVCLLGTVGLFL 502          

Query:  183 RRLYDDLMRRRGYDPSVRPVKSYTSTVLLYMNLSLVQILDVDEKNQIIVLNMWVNQEWNDPNFVWDPNDYGNVTELNIPSREIWTPDLVLYNNAGGDWDLASSSNTKVIVNHDGSVLWKPPIIFKSQCGINVEFFPFDKQLCDLKIGTWTHNGFLIDLRHTAQKNQSQASFDNCNAKIDYAIDLSQYVNNVEWDLLEVSAKRNIEFYPCCTEPYLDISFNVSLRRRTLFYGINLICPCLAISFLTILVFYLPADSGEKXXXXXXXXXXXXXXXXXXXDISPPTSIVVPLILKYLLFTMILVTLSVMATVLVLNIHWRSPDTHKMAPWVRSVFTSTLPKLLFMKKPD--------QDYRDNETDDIP----ETFHEDETDSNIQDKW---------STRRAAV---------SGDNVVNEIELALEGVRRIVHHIKKENSYSAMRDDWKYVAVVLDRLFLWLFSIAAIIGMLGIFMQAPTLTD 1538
             RLY+DL++   Y+P +RPV + +  V+L+  +S+ Q++ VDE NQI+  N+W+   WND    W+P+DYG +  L IP+ +IW PD+VLYNNA G + +      K +V + G V W PP IFKS C I+V FFPFD Q C LK G+WT++   I+L     K                 I+L ++  + EW ++     ++   Y CC E Y DI++++ +RR  LFY I +I PCL IS LTILVFYLP+D GEKV+L +S+LLSLTVF L+I +I P TS+V+PLI +YLLFTMI VTLS++ TV VLN+H+R+P TH M  WV+  F   LPK++FM +P+        Q Y D  + +I     + F++D + +  Q K           TR +++         SG  +  EI  A+E V  I  ++K ++    ++DDWKYVA+V+DR+FLW+F +  I+G  G+F+Q    +D
Sbjct:   26 HRLYEDLLK--SYNPYIRPVMNVSDPVILHFEVSMSQLVKVDEVNQIMETNLWLRHLWNDYKLKWNPSDYGGIEFLRIPASQIWRPDIVLYNNAVGAFHV--DDKAKAVVRYSGDVTWIPPAIFKSSCKIDVTFFPFDYQNCSLKFGSWTYDKAKINLVMIGSK-----------------INLKEFWESGEWVIINAPGYKHEIKYNCCVEIYQDITYSLYIRRLPLFYTIYIIIPCLLISCLTILVFYLPSDCGEKVTLCMSVLLSLTVFLLVITEIIPSTSLVIPLIGEYLLFTMIFVTLSIVITVFVLNVHYRTPKTHTMPHWVKRFFLHLLPKVMFMTRPEKQPYALKPQAYLDISSSEIRSCQDQLFYQDSSCACGQLKRLYTSDTACNVTRGSSLESMYNLGLHSGSGLSPEIREAIEDVHFIAENMKAQDEAKEVQDDWKYVAMVIDRIFLWVFVLVCILGTAGLFLQPLLFSD 486          

Query:  183 RRLYDDLMRRRGYDPSVRPVKSYTSTVLLYMNLSLVQILDVDEKNQIIVLNMWVNQEWNDPNFVWDPNDYGNVTELNIPSREIWTPDLVLYNNAGGDWDLASSSNTKVIVNHDGSVLWKPPIIFKSQCGINVEFFPFDKQLCDLKIGTWTHNGFLIDLRHTAQKNQSQASFDNCNAKIDYAIDLSQYVNNVEWDLLEVSAKRNIEFYPCCTEPYLDISFNVSLRRRTLFYGINLICPCLAISFLTILVFYLPADSGEKXXXXXXXXXXXXXXXXXXXDISPPTSIVVPLILKYLLFTMILVTLSVMATVLVLNIHWRSPDTHKMAPWVRSVFTSTLPKLLFMKKPD--------QDYRDNETDDIP----ETFHEDETDSNIQDKW---------STRRAAV---------SGDNVVNEIELALEGVRRIVHHIKKENSYSAMRDDWKYVAVVLDRLFLWLFSIAAIIGMLGIFMQAPTLTD 1538
             RLY+DL++   Y+P +RPV + +  V+L+  +S+ Q++ VDE NQI+  N+W+   WND    W+P+DYG +  L IP+ +IW PD+VLYNNA G + +      K +V + G V W PP IFKS C I+V FFPFD Q C LK G+WT++   I+L     K                 I+L ++  + EW ++     ++   Y CC E Y DI++++ +RR  LFY I +I PCL IS LTILVFYLP+D GEKV+L +S+LLSLTVF L+I +I P TS+V+PLI +YLLFTMI VTLS++ TV VLN+H+R+P TH M  WV+  F   LPK++FM +P+        Q Y D  + +I     + F++D + +  Q K           TR +++         SG  +  EI  A+E V  I  ++K ++    ++DDWKYVA+V+DR+FLW+F +  I+G  G+F+Q    +D
Sbjct:   21 HRLYEDLLK--SYNPYIRPVMNVSDPVILHFEVSMSQLVKVDEVNQIMETNLWLRHLWNDYKLKWNPSDYGGIEFLRIPASQIWRPDIVLYNNAVGAFHV--DDKAKAVVRYSGDVTWIPPAIFKSSCKIDVTFFPFDYQNCSLKFGSWTYDKAKINLVMIGSK-----------------INLKEFWESGEWVIINAPGYKHEIKYNCCVEIYQDITYSLYIRRLPLFYTIYIIIPCLLISCLTILVFYLPSDCGEKVTLCMSVLLSLTVFLLVITEIIPSTSLVIPLIGEYLLFTMIFVTLSIVITVFVLNVHYRTPKTHTMPHWVKRFFLHLLPKVMFMTRPEKQPYALKPQAYLDISSSEIRSCQDQLFYQDSSCACGQLKRLYTSDTACNVTRGSSLESMYNLGLHSGSGLSPEIREAIEDVHFIAENMKAQDEAKEVQDDWKYVAMVIDRIFLWVFVLVCILGTAGLFLQPLLFSD 481          

Query:  183 RRLYDDLMRRRGYDPSVRPVKSYTSTVLLYMNLSLVQILDVDEKNQIIVLNMWVNQEWNDPNFVWDPNDYGNVTELNIPSREIWTPDLVLYNNAGGDWDLASSSNTKVIVNHDGSVLWKPPIIFKSQCGINVEFFPFDKQLCDLKIGTWTHNGFLIDLRHTAQKNQSQASFDNCNAKIDYAIDLSQYVNNVEWDLLEVSAKRNIEFYPCCTEPYLDISFNVSLRRRTLFYGINLICPCLAISFLTILVFYLPADSGEKXXXXXXXXXXXXXXXXXXXDISPPTSIVVPLILKYLLFTMILVTLSVMATVLVLNIHWRSPDTHKMAPWVRSVFTSTLPKLLFMKKPD--------QDYRDNETDDIP----ETFHEDETDSNIQDKW---------STRRAAV---------SGDNVVNEIELALEGVRRIVHHIKKENSYSAMRDDWKYVAVVLDRLFLWLFSIAAIIGMLGIFMQAPTLTD 1538
             RLY+DL++   Y+P +RPV + +  V+L+  +S+ Q++ VDE NQI+  N+W+   WND    W+P+DYG +  L IP+ +IW PD+VLYNNA G + +      K +V + G V W PP IFKS C I+V FFPFD Q C LK G+WT++   I+L     K                 I+L ++  + EW ++     ++   Y CC E Y DI++++ +RR  LFY I +I PCL IS LTILVFYLP+D GEKV+L +S+LLSLTVF L+I +I P TS+V+PLI +YLLFTMI VTLS++ TV VLN+H+R+P TH M  WV+  F   LPK++FM +P+        Q Y D  + +I     + F++D + +  Q K           TR +++         SG  +  EI  A+E V  I  ++K ++    ++DDWKYVA+V+DR+FLW+F +  I+G  G+F+Q    +D
Sbjct:   29 HRLYEDLLK--SYNPYIRPVMNVSDPVILHFEVSMSQLVKVDEVNQIMETNLWLRHLWNDYKLKWNPSDYGGIEFLRIPASQIWRPDIVLYNNAVGAFHV--DDKAKAVVRYSGDVTWIPPAIFKSSCKIDVTFFPFDYQNCSLKFGSWTYDKAKINLVMIGSK-----------------INLKEFWESGEWVIINAPGYKHEIKYNCCVEIYQDITYSLYIRRLPLFYTIYIIIPCLLISCLTILVFYLPSDCGEKVTLCMSVLLSLTVFLLVITEIIPSTSLVIPLIGEYLLFTMIFVTLSIVITVFVLNVHYRTPKTHTMPHWVKRFFLHLLPKVMFMTRPEKQPYALKPQAYLDISSSEIRSCQDQLFYQDSSCACGQLKRLYTSDTACNVTRGSSLESMYNLGLHSGSGLSPEIREAIEDVHFIAENMKAQDEAKEVQDDWKYVAMVIDRIFLWVFVLVCILGTAGLFLQPLLFSD 489          

Query:  183 RRLYDDLMRRRGYDPSVRPVKSYTSTVLLYMNLSLVQILDVDEKNQIIVLNMWVNQEWNDPNFVWDPNDYGNVTELNIPSREIWTPDLVLYNNAGGDWDLASSSNTKVIVNHDGSVLWKPPIIFKSQCGINVEFFPFDKQLCDLKIGTWTHNGFLIDLRHTAQKNQSQASFDNCNAKIDYAIDLSQYVNNVEWDLLEVSAKRNIEFYPCCTEPYLDISFNVSLRRRTLFYGINLICPCLAISFLTILVFYLPADSGEKXXXXXXXXXXXXXXXXXXXDISPPTSIVVPLILKYLLFTMILVTLSVMATVLVLNIHWRSPDTHKMAPWVRSVFTSTLPKLLFMKKPD--------QDYRDNETDDIP----ETFHEDETDSNIQDKW---------STRRAAV---------SGDNVVNEIELALEGVRRIVHHIKKENSYSAMRDDWKYVAVVLDRLFLWLFSIAAIIGMLGIFMQ 1520
             RLY+DL++   Y+P +RPV + +  V+L+  +S+ Q++ VDE NQI+  N+W+   WND    W+P+DYG +  L IP+ +IW PD+VLYNNA G + +      K +V + G V W PP IFKS C I+V FFPFD Q C LK G+WT++   I+L     K                 I+L ++  + EW ++     ++   Y CC E Y DI++++ +RR  LFY I +I PCL IS LTILVFYLP+D GEKV+L +S+LLSLTVF L+I +I P TS+V+PLI +YLLFTMI VTLS++ TV VLN+H+R+P TH M  WV+  F   LPK++FM +P+        Q Y D  + +I     + F++D + +  Q K           TR +++         SG  +  EI  A+E V  I  ++K ++    ++DDWKYVA+V+DR+FLW+F +  I+G  G+F+Q
Sbjct:   32 HRLYEDLLK--SYNPYIRPVMNVSDPVILHFEVSMSQLVKVDEVNQIMETNLWLRHLWNDYKLKWNPSDYGGIEFLRIPASQIWRPDIVLYNNAVGAFHV--DDKAKAVVRYSGDVTWIPPAIFKSSCKIDVTFFPFDYQNCSLKFGSWTYDKAKINLVMIGSK-----------------INLKEFWESGEWVIINAPGYKHEIKYNCCVEIYQDITYSLYIRRLPLFYTIYIIIPCLLISCLTILVFYLPSDCGEKVTLCMSVLLSLTVFLLVITEIIPSTSLVIPLIGEYLLFTMIFVTLSIVITVFVLNVHYRTPKTHTMPHWVKRFFLHLLPKVMFMTRPEKQPYALKPQAYLDISSSEIRSCQDQLFYQDSSCACGQLKRLYTSDTACNVTRGSSLESMYNLGLHSGSGLSPEIREAIEDVHFIAENMKAQDEAKEVQDDWKYVAMVIDRIFLWVFVLVCILGTAGLFLQ 486          

Query:  102 QFELIFTMICLGFLFGLIFIVQG--TKDARRLYDDLMRRRGYDPSVRPVKSYTSTVLLYMNLSLVQILDVDEKNQIIVLNMWVNQEWNDPNFVWDPNDYGNVTELNIPSREIWTPDLVLYNNAGGDWDLASSSNTKVIVNHDGSVLWKPPIIFKSQCGINVEFFPFDKQLCDLKIGTWTHNGFLIDLRHTAQKNQSQASFDNCNAKIDYAIDLSQYVNNVEWDLLEVSAKRNIEFYPCCTEPYLDISFNVSLRRRTLFYGINLICPCLAISFLTILVFYLPADSGEKXXXXXXXXXXXXXXXXXXXDISPPTSIVVPLILKYLLFTMILVTLSVMATVLVLNIHWRSPDTHKMAPWVRSVFTSTLPKLLFMKK--PDQDYRDNETDDIPETFHEDETDSNIQDKWS---------------------TRRAAVSGDNVVN---------------------EIELALEGVRRIVHHIKKENSYSAMRDDWKYVAVVLDRLFLWLFSIAAIIGMLGIFM 1517
            QF +   + CL  L   +   QG  T    RL+  L    GY+   RPV + +  V++   LS+ Q++DVDEKNQ++  N+W+ QEWND    WDP ++GN+T L +PS  IW PD+VLYNNA G  + A +  TK  +   G+V W PP I+KS C I+V FFPFD+Q C +K G+WT++   IDL                  +++  +DL  Y  + EW ++  +   N + Y CC E Y D+++   +RR  LFY INLI PCL IS LT+LVFYLP++ GEK++L IS+LLSLTVF LLI +I P TS+V+PLI +YLLFTMI VTLS++ TV VLN+H RSP TH M  WVR      +P+ L M +  P  +   +    +  T+H  ET+ + +++                       +    + G   ++                     +I+ ALEGV  I  H++ E++ S++++DWKYVA+V+DR+FLWLF I   +G +G+F+
Sbjct:    9 QFWIHLYLWCL-LLMPAVLAQQGSHTHAEDRLFKHLFG--GYNRWARPVPNTSDVVIVRFGLSIAQLIDVDEKNQMMTTNVWLKQEWNDYKLRWDPAEFGNITSLRVPSEMIWIPDIVLYNNADG--EFAVTHMTKAHLFFTGTVHWVPPAIYKSSCSIDVTFFPFDQQNCKMKFGSWTYDKAKIDLE-----------------QMERTVDLKDYWESGEWAIINATGTYNSKKYDCCAEIYPDVTYYFVIRRLPLFYTINLIIPCLLISCLTVLVFYLPSECGEKITLCISVLLSLTVFLLLITEIIPSTSLVIPLIGEYLLFTMIFVTLSIVITVFVLNVHHRSPSTHNMPNWVRVALLGRVPRWLMMNRPLPPMELHGSPGLKLSPTYHWLETNMDAEEREETEEEEEEEEDENICMCAGLPDSSMGVLYGHGSLHLRAMGPEAKTPSQASEILLSPQIQKALEGVHYIADHLRSEDADSSVKEDWKYVAMVVDRIFLWLFIIVCFLGTIGLFL 504          

Query:  102 QFELIFTMICLGFLFGLIFIVQG--TKDARRLYDDLMRRRGYDPSVRPVKSYTSTVLLYMNLSLVQILDVDEKNQIIVLNMWVNQEWNDPNFVWDPNDYGNVTELNIPSREIWTPDLVLYNNAGGDWDLASSSNTKVIVNHDGSVLWKPPIIFKSQCGINVEFFPFDKQLCDLKIGTWTHNGFLIDLRHTAQKNQSQASFDNCNAKIDYAIDLSQYVNNVEWDLLEVSAKRNIEFYPCCTEPYLDISFNVSLRRRTLFYGINLICPCLAISFLTILVFYLPADSGEKXXXXXXXXXXXXXXXXXXXDISPPTSIVVPLILKYLLFTMILVTLSVMATVLVLNIHWRSPDTHKMAPWVRSVFTSTLPKLLFMKK--PDQDYRDNETDDIPETFHEDETDSNIQDKWS---------------------TRRAAVSGDNVVN---------------------EIELALEGVRRIVHHIKKENSYSAMRDDWKYVAVVLDRLFLWLFSIAAIIGMLGIFM 1517
            QF +   + CL  L   +   QG  T    RL+  L    GY+   RPV + +  V++   LS+ Q++DVDEKNQ++  N+W+ QEWND    WDP ++GN+T L +PS  IW PD+VLYNNA G  + A +  TK  +   G+V W PP I+KS C I+V FFPFD+Q C +K G+WT++   IDL                  +++  +DL  Y  + EW ++  +   N + Y CC E Y D+++   +RR  LFY INLI PCL IS LT+LVFYLP++ GEK++L IS+LLSLTVF LLI +I P TS+V+PLI +YLLFTMI VTLS++ TV VLN+H RSP TH M  WVR      +P+ L M +  P  +   +    +  T+H  ET+ + +++                       +    + G   ++                     +I+ ALEGV  I  H++ E++ S++++DWKYVA+V+DR+FLWLF I   +G +G+F+
Sbjct:    9 QFWIHLYLWCL-LLMPAVLAQQGSHTHAEDRLFKHLFG--GYNRWARPVPNTSDVVIVRFGLSIAQLIDVDEKNQMMTTNVWLKQEWNDYKLRWDPAEFGNITSLRVPSEMIWIPDIVLYNNADG--EFAVTHMTKAHLFFTGTVHWVPPAIYKSSCSIDVTFFPFDQQNCKMKFGSWTYDKAKIDLE-----------------QMERTVDLKDYWESGEWAIINATGTYNSKKYDCCAEIYPDVTYYFVIRRLPLFYTINLIIPCLLISCLTVLVFYLPSECGEKITLCISVLLSLTVFLLLITEIIPSTSLVIPLIGEYLLFTMIFVTLSIVITVFVLNVHHRSPSTHNMPNWVRVALLGRVPRWLMMNRPLPPMELHGSPGLKLSPTYHWLETNMDAEEREETEEEEEEEEDENICMCAGLPDSSMGVLYGHGSLHLRAMGPEAKTPSQASEILLSPQIQKALEGVHYIADHLRSEDADSSVKEDWKYVAMVVDRIFLWLFIIVCFLGTIGLFL 504          

Query:  126 ICL---GFLFGLIFIVQGTKDARRLYDDLMRRRGYDPSVRPVKSYTSTVLLYMNLSLVQILDVDEKNQIIVLNMWVNQEWNDPNFVWDPNDYGNVTELNIPSREIWTPDLVLYNNAGGDWDLASSSNTKVIVNHDGSVLWKPPIIFKSQCGINVEFFPFDKQLCDLKIGTWTHNGFLIDLRHTAQKNQSQASFDNCNAKIDYAIDLSQYVNNVEWDLLEVSAKRNIEFYPCCTEPYLDISFNVSLRRRTLFYGINLICPCLAISFLTILVFYLPADSGEKXXXXXXXXXXXXXXXXXXXDISPPTSIVVPLILKYLLFTMILVTLSVMATVLVLNIHWRSPDTHKMAPWVRSVFTSTLPKLLFMKKPDQDYRD----------------------NETDDIPETFH-EDETDSNIQDKWSTRRAA---VSGDNVVNEIELALEGVRRIVHHIKKENSYSAMRDDWKYVAVVLDRLFLWLFSIAAIIGMLGIFMQ 1520
            +CL   GFL  L     G +   +L+  L     Y+  +RPV++ +  V ++  L++ Q+ +VDE NQI+  N+W+   W D    WDP +Y  +  L +P+  IW PD+VLYNNA GD+ +     TK ++ +DG + W PP IFKS C +++ FFPFD Q C LK G+WT++   IDL     K                 +D++ +  N EW++++ S  ++   Y CC E Y DI+++  +RR  +FY INLI PCL ISFLT+LVFYLP+D GEKV+L IS+LLSLTVF L+I +  P TS+V+PL+ +YLLFTMI VTLS++ TV VLNIH+R+P TH M  WV+++F    P +L M+KP    ++                       E+  + E  H +  +D     + S+++ A          +++E  +E V+ I  ++K  N  + + DDWKY+A+V+DR+FLW+F I  + G +G+F+Q
Sbjct:   14 LCLWLCGFL-ALFKGSTGCESEEQLFHRLFAH--YNRFIRPVENVSDPVTVHFELAITQLANVDEVNQIMETNLWLRHIWKDYRLRWDPTEYDGIETLRVPADNIWKPDIVLYNNAVGDFQV--EGKTKALLKYDGVITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAEIDLLIIGSK-----------------VDMNDFWENSEWEIVDASGYKHDIKYNCCEEIYTDITYSFYIRRLPMFYTINLIIPCLFISFLTVLVFYLPSDCGEKVTLCISVLLSLTVFLLVITETIPSTSLVIPLVGEYLLFTMIFVTLSIVVTVFVLNIHYRTPATHTMPKWVKTIFLQAFPSILMMRKPLDKTKEAGGVKDPKSHTKRPAKVKFTHRGESKLLKECHHCQKSSDIAPGKRRSSQQPARWVAENSEHSSDVEDVIESVQFIAENMKSHNETNEVEDDWKYMAMVVDRVFLWVFIIVCVFGTVGLFLQ 485          

Query:  159 IVQGTKDARRLYDDLMRRRGYDPSVRPVKSYTSTVLLYMNLSLVQILDVDEKNQIIVLNMWVNQEWNDPNFVWDPNDYGNVTELNIPSREIWTPDLVLYNNAGGDWDLASSSNTKVIVNHDGSVLWKPPIIFKSQCGINVEFFPFDKQLCDLKIGTWTHNGFLIDLRHTAQKNQSQASFDNCNAKIDYAIDLSQYVNNVEWDLLEVSAKRNIEFYPCCTEPYLDISFNVSLRRRTLFYGINLICPCLAISFLTILVFYLPADSGEKXXXXXXXXXXXXXXXXXXXDISPPTSIVVPLILKYLLFTMILVTLSVMATVLVLNIHWRSPDTHKMAPWVRSVFTSTLPKLLFMKKPDQDYRD--------------------NETDDIPETF-----------HEDETDSNIQDKWSTRRAAVSGDNVVN------EIELALEGVRRIVHHIKKENSYSAMRDDWKYVAVVLDRLFLWLFSIAAIIGMLGIFMQ 1520
            +   ++   RL+  L     Y+  +RPV + +  V++   +S+ Q++ VDE NQI+  N+W+ Q WND    W P+DY  V  + +P+ +IW PD+VLYNNA GD+ +     TK ++ + G V W PP IFKS C I+V +FPFD Q C +K G+W+++   IDL                   I  +++L  Y  + EW +++    ++   Y CC E Y DI++++ +RR  LFY INLI PCL ISFLT+LVFYLP+D GEKV+L IS+LLSLTVF L+I +  P TS+V+PLI +YLLFTMI VTLS++ TV VLN+H+R+P TH M  WV++VF + LP+++FM +P     D                     ++    E +           H     SN     +   ++ S D V++      EI+ A++ V+ I  ++K +N    ++DDWKYVA+V+DR+FLW+F +  I+G  G+F+Q
Sbjct:   22 VASASEAEHRLFQYLFE--DYNEIIRPVANVSHPVIIQFEVSMSQLVKVDEVNQIMETNLWLKQIWNDYKLKWKPSDYQGVEFMRVPAEKIWKPDIVLYNNADGDFQV--DDKTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDL-----------------VLIGSSMNLKDYWESGEWAIIKAPGYKHEIKYNCCEEIYQDITYSLYIRRLPLFYTINLIIPCLLISFLTVLVFYLPSDCGEKVTLCISVLLSLTVFLLVITETIPSTSLVIPLIGEYLLFTMIFVTLSIVITVFVLNVHYRTPTTHTMPTWVKAVFLNLLPRVMFMTRPTSTEEDAPKTRNFYGAELSNLNCFSRADSKSCKEGYPCQDGTCGYCHHRRVKISNFSANLTRSSSSESVDAVLSLSALSPEIKEAIQSVKYIAENMKAQNVAKEIQDDWKYVAMVIDRIFLWVFILVCILGTAGLFLQ 491          

Query:  159 IVQGTKDARRLYDDLMRRRGYDPSVRPVKSYTSTVLLYMNLSLVQILDVDEKNQIIVLNMWVNQEWNDPNFVWDPNDYGNVTELNIPSREIWTPDLVLYNNAGGDWDLASSSNTKVIVNHDGSVLWKPPIIFKSQCGINVEFFPFDKQLCDLKIGTWTHNGFLIDLRHTAQKNQSQASFDNCNAKIDYAIDLSQYVNNVEWDLLEVSAKRNIEFYPCCTEPYLDISFNVSLRRRTLFYGINLICPCLAISFLTILVFYLPADSGEKXXXXXXXXXXXXXXXXXXXDISPPTSIVVPLILKYLLFTMILVTLSVMATVLVLNIHWRSPDTHKMAPWVRSVFTSTLPKLLFMKKPDQDYRD--------------------NETDDIPETF-----------HEDETDSNIQDKWSTRRAAVSGDNVVN------EIELALEGVRRIVHHIKKENSYSAMRDDWKYVAVVLDRLFLWLFSIAAIIGMLGIFMQ 1520
            +   ++   RL+  L     Y+  +RPV + +  V++   +S+ Q++ VDE NQI+  N+W+ Q WND    W P+DY  V  + +P+ +IW PD+VLYNNA GD+ +     TK ++ + G V W PP IFKS C I+V +FPFD Q C +K G+W+++   IDL                   I  +++L  Y  + EW +++    ++   Y CC E Y DI++++ +RR  LFY INLI PCL ISFLT+LVFYLP+D GEKV+L IS+LLSLTVF L+I +  P TS+V+PLI +YLLFTMI VTLS++ TV VLN+H+R+P TH M  WV++VF + LP+++FM +P     D                     ++    E +           H     SN     +   ++ S D V++      EI+ A++ V+ I  ++K +N    ++DDWKYVA+V+DR+FLW+F +  I+G  G+F+Q
Sbjct:   27 VASASEAEHRLFQYLFE--DYNEIIRPVANVSHPVIIQFEVSMSQLVKVDEVNQIMETNLWLKQIWNDYKLKWKPSDYQGVEFMRVPAEKIWKPDIVLYNNADGDFQV--DDKTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDL-----------------VLIGSSMNLKDYWESGEWAIIKAPGYKHEIKYNCCEEIYQDITYSLYIRRLPLFYTINLIIPCLLISFLTVLVFYLPSDCGEKVTLCISVLLSLTVFLLVITETIPSTSLVIPLIGEYLLFTMIFVTLSIVITVFVLNVHYRTPTTHTMPTWVKAVFLNLLPRVMFMTRPTSTEEDAPKTRNFYGAELSNLNCFSRADSKSCKEGYPCQDGTCGYCHHRRVKISNFSANLTRSSSSESVDAVLSLSALSPEIKEAIQSVKYIAENMKAQNVAKEIQDDWKYVAMVIDRIFLWVFILVCILGTAGLFLQ 496          

Query:  138 FLFGLIFIVQGTK---DARRLYDDLMRRRGYDPSVRPVKSYTSTVLLYMNLSLVQILDVDEKNQIIVLNMWVNQEWNDPNFVWDPNDYGNVTELNIPSREIWTPDLVLYNNAGGDWDLASSSNTKVIVNHDGSVLWKPPIIFKSQCGINVEFFPFDKQLCDLKIGTWTHNGFLIDLRHTAQKNQSQASFDNCNAKIDYAIDLSQYVNNVEWDLLEVSAKRNIEFYPCCTEPYLDISFNVSLRRRTLFYGINLICPCLAISFLTILVFYLPADSGEKXXXXXXXXXXXXXXXXXXXDISPPTSIVVPLILKYLLFTMILVTLSVMATVLVLNIHWRSPDTHKMAPWVRSVFTSTLPKLLFMKKPDQDYRDNET------DDIPETFHEDETDSNIQDKWSTRRA--------------------AVSGDNVVNEIELALEGVRRIVHHIKKENSYSAMRDDWKYVAVVLDRLFLWLFSIAAIIGMLGIFMQAPTLTDNAIPM 1553
            +L G++    G     DA+RLYDDL+    Y+  VRPV + +  + + + L L Q++DV+ KNQI+  N+WV Q W D    W+P +YG V  L++PS  IW PD+VLYNNA G++++  +  TK  +N+ G V W+PP I+KS C I+VE+FPFD+Q C +K G+WT++GF +DLRH  +   +          ++  +DLS++  +VEWD+LEV A RN +FY CC EPYLDI+FN+++RR+TLFY +NLI PC+ ISFLT+LVFYLP+DSGEKVSLSISILLSLTVFFLL+ +I PPTS+VVPL+ K++LFTMIL T S+  TV+VLN+H+RSP TH M+PWVR VF   LP+LL M++P      + +          ET   DE    +                             A+   +   E+  A++G+  I    +KE   + +++DWKYVA+VLDR FLW+F++A ++G  GI +QAPTL D   P+
Sbjct:    8 YLHGVVLFATGCAGNPDAKRLYDDLLS--NYNKLVRPVLNVSDALTVRIKLKLSQLIDVNLKNQIMTTNLWVEQSWYDYKLSWEPREYGGVEMLHVPSDHIWRPDIVLYNNADGNFEVTLA--TKATLNYTGRVEWRPPAIYKSSCEIDVEYFPFDQQTCVMKFGSWTYDGFQVDLRHIDEVRGTNV--------VELGVDLSEFYTSVEWDILEVPAVRNEKFYTCCDEPYLDITFNITMRRKTLFYTVNLIIPCMGISFLTVLVFYLPSDSGEKVSLSISILLSLTVFFLLLAEIIPPTSLVVPLLGKFVLFTMILDTFSICVTVVVLNVHFRSPQTHTMSPWVRRVFIHVLPRLLVMRRPHYRLDPHRSRFAGLVTGAGETTLWDEGSPGVPAPPRPPPCAPPLAPCAACAPAEAPALCDALRRWHRCPELHKAIDGINYIADQTRKEEESTRVKEDWKYVAMVLDRPFLWIFTLAVVVGSAGIILQAPTLYDERAPI 496          

Query:  165 QGTKDARRLYDDLMRRRGYDPSVRPVKSYTSTVLLYMNLSLVQILDVDEKNQIIVLNMWVNQEWNDPNFVWDPNDYGNVTELNIPSREIWTPDLVLYNNAGGDWDLASSSNTKVIVNHDGSVLWKPPIIFKSQCGINVEFFPFDKQLCDLKIGTWTHNGFLIDLRHTAQKNQSQASFDNCNAKIDYAIDLSQYVNNVEWDLLEVSAKRNIEFYPCCTEPYLDISFNVSLRRRTLFYGINLICPCLAISFLTILVFYLPADSGEKXXXXXXXXXXXXXXXXXXXDISPPTSIVVPLILKYLLFTMILVTLSVMATVLVLNIHWRSPDTHKMAPWVRSVFTSTLPKLLFMKKPD---QDYRD--------NETD------DIPETFHEDE---TDSNIQDKWSTRRAAVSGDNVVNEIELALEGVRRIVHHIKKENSYSAMRDDWKYVAVVLDRLFLWLFSIAAIIGMLGIFMQAPTLTDNAIPM 1553
            +   D +RLYDDL+    Y+  +RPV + T T+ +++ L L Q+++V+ KNQ++  N+WV Q W D    WDP +YG V +L +PS  IW PD+VLYNN  G++++  +  TK  + + G V W+PP I+KS C +NVE+FP+D+Q+C +K G+WT+NG  +DL+H  Q   S          +   IDL+++  +VEWD+LEV A +N E+YP   EP+ DI+F +++RR+TLFY +NLI PC+A++FLT+LVFYLP+DSGEKV+L ISIL+SLTVFFLL+ +I PPTS+ VPL+ KYLLFTMILV+LSV  TV VLNIH+RSP TH M+P VR +F   +PKL+ M++      DY D        NE D      D P  F + +    D+ +Q+  S     V   N+  E+  AL  VR I  HIK  +  + + +DWK+V++VLDR FLWLF+++ + G L I  Q+P+L D   P+
Sbjct:   25 EANPDTKRLYDDLLS--NYNRLIRPVVNNTETLTVWLGLKLSQLIEVNLKNQVMTTNLWVKQRWFDYKLRWDPEEYGGVEQLYVPSEHIWVPDIVLYNNWDGNYEV--TLMTKATLKYTGEVFWEPPAIYKSSCEMNVEYFPYDEQICFMKFGSWTYNGAQVDLKHLDQIPGSNL--------VQVGIDLTEFYLSVEWDILEVPATKNEEYYPDTLEPFSDITFKLTMRRKTLFYTVNLIVPCVALTFLTVLVFYLPSDSGEKVTLCISILVSLTVFFLLLAEIIPPTSLAVPLLGKYLLFTMILVSLSVWTTVCVLNIHFRSPSTHNMSPLVRKLFLHFMPKLMMMRRTQYTLPDYDDSTPSNGYTNEIDVRDSISDFPSEFKDSQDGAYDNGMQN--SVDSDNVIPRNLTPEVLQALRAVRFIAQHIKDADKDNEIVEDWKFVSMVLDRFFLWLFTLSCVFGTLAIICQSPSLYDTRSPI 493          

Query:  162 VQGTKDARRLYDDLMRRRGYDPSVRPVKSYTSTVLLYMNLSLVQILDVDEKNQIIVLNMWVNQEWNDPNFVWDPNDYGNVTELNIPSREIWTPDLVLYNNAGGDWDLASSSNTKVIVNHDGSVLWKPPIIFKSQCGINVEFFPFDKQLCDLKIGTWTHNGFLIDLRHTAQKNQSQASFDNCNAKIDYAIDLSQYVNNVEWDLLEVSAKRNIEFYPCCTEPYLDISFNVSLRRRTLFYGINLICPCLAISFLTILVFYLPADSGEKXXXXXXXXXXXXXXXXXXXDISPPTSIVVPLILKYLLFTMILVTLSVMATVLVLNIHWRSPDTHKMAPWVRSVFTSTLPKLLFMKKPDQDYRDNETDDI 1253
            VQ   DA+RLYDDL+    Y+  +RPV + T TVL+ + L L Q++D++ K+QI+  N+W+  EW D  F WDP++YG VTEL +PS  IW PD+VLYNNA G++    ++ TK I+++ G V+W PP IFKS C I+V +FPFD+Q C +K G+WT++G  IDL+H +QKN      DN   K++  IDL +Y  +VEWD+L V A+R+ ++YPCC EPY DI FN++LRR+TLFY +NLI PC+ IS+L++LVFYLPADSGEK++L ISILLS T+FFLLI +I P TS+ +PL+ KYLLFTM+LV LSV+ T+++LNIH+R P THKM PW+RS F   LPKLL M+ P    RD   + I
Sbjct:   39 VQANPDAKRLYDDLLS--NYNRLIRPVSNNTDTVLVKLGLRLSQLIDLNLKDQILTTNVWLEHEWQDHKFKWDPSEYGGVTELYVPSEHIWLPDIVLYNNADGEY--VVTTMTKAILHYTGKVVWTPPAIFKSSCEIDVRYFPFDQQTCFMKFGSWTYDGDQIDLKHISQKNDK----DN---KVEIGIDLREYYPSVEWDILGVPAERHEKYYPCCAEPYPDIFFNITLRRKTLFYTVNLIIPCVGISYLSVLVFYLPADSGEKIALCISILLSQTMFFLLISEIIPSTSLALPLLGKYLLFTMLLVGLSVVITIIILNIHYRKPSTHKMRPWIRSFFIKRLPKLLLMRVPKDLLRDLAANKI 391          

Query: 1347 EIELALEGVRRIVHHIKKENSYSAMRDDWKYVAVVLDRLFLWLFSIAAIIGMLGIFMQAPTLTDNA 1544
            E+E A+  V  I HH+++++ ++A   DW +VA+V+DRLFLWLF IA+++G   I  +AP+L D+ 
Sbjct:  489 ELEKAIHNVMFIQHHMQRQDEFNAEDQDWGFVAMVMDRLFLWLFMIASLVGTFVILGEAPSLYDDT 554          

Query:  177 DARRLYDDLMRRRGYDPSVRPVKSYTSTVLLYMNLSLVQILDVDEKNQIIVLNMWVNQEWNDPNFVWDPNDYGNVTELNIPSREIWTPDLVLYNNAGGDWDLASSSNTKVIVNHDGSVLWKPPIIFKSQCGINVEFFPFDKQLCDLKIGTWTHNGFLIDLRHTAQKNQSQASFDNCNAKIDYAIDLSQYVNNVEWDLLEVSAKRNIEFYPCCTEPYLDISFNVSLRRRTLFYGINLICPCLAISFLTILVFYLPADSGEKXXXXXXXXXXXXXXXXXXXDISPPTSIVVPLILKYLLFTMILVTLSVMATVLVLNIHWRSPDTHKMAPWVRSVFTSTLPKLLFMKKPDQ 1223
            DA+RLYDDL+    Y+  +RPV + T TVL+ + L L Q++D++ K+QI+  N+W+  EW D  F WDP +YG VTEL +PS  IW PD+VLYNNA G++    ++ TK +++H G V+W PP IFKS C I+V +FPFD+Q C +K G+WT++G  IDL+H  QK      +D+   K+   IDL +Y  +VEWD+L V A+R+ ++YPCC EPY DI FN++LRR+TLFY +NLI PC+ IS+L++LVFYLPADSGEK++L ISILLS T+FFLLI +I P TS+ +PL+ KYLLFTM+LV LSV+ T++VLN+H+R P THKMAPWVR VF   LPKLL M+ P+Q
Sbjct:   26 DAKRLYDDLLS--NYNRLIRPVSNNTDTVLVKLGLRLSQLIDLNLKDQILTTNVWLEHEWQDHKFRWDPAEYGGVTELYVPSEHIWLPDIVLYNNADGEY--VVTTMTKAVLHHTGKVVWTPPAIFKSSCEIDVRYFPFDQQTCFMKFGSWTYDGDQIDLKHINQK------YDDNKVKV--GIDLREYYPSVEWDILGVPAERHEKYYPCCAEPYPDIFFNITLRRKTLFYTVNLIVPCVGISYLSVLVFYLPADSGEKIALCISILLSQTMFFLLISEIIPSTSLALPLLGKYLLFTMVLVGLSVVITIMVLNVHYRKPSTHKMAPWVRKVFIRRLPKLLLMRVPEQ 362          

Query: 1347 EIELALEGVRRIVHHIKKENSYSAMRDDWKYVAVVLDRLFLWLFSIAAIIGMLGIFMQAPTLTDNAIPM 1553
            E+E A+  V  I +H+++++ + A   DW +VA+VLDRLFLW+F+IA+I+G   I  +AP L D+  P+
Sbjct:  471 ELEKAIHNVLFIQNHMQRQDEFDAEDQDWGFVAMVLDRLFLWIFTIASIVGTFAILCEAPALYDDTKPI 539          

Query:  141 LFGLIFIVQ-------GTKDARRLYDDLMRRRGYDPSVRPVKSYTSTVLLYMNLSLVQILDVDEKNQIIVLNMWVNQEWNDPNFVWDPNDYGNVTELNIPSREIWTPDLVLYNNAGGDWDLASSSNTKVIVNHDGSVLWKPPIIFKSQCGINVEFFPFDKQLCDLKIGTWTHNGFLIDLRHTAQKNQSQASFDNCNAKIDYAIDLSQYVNNVEWDLLEVSAKRNIEFYPCCTEPYLDISFNVSLRRRTLFYGINLICPCLAISFLTILVFYLPADSGEKXXXXXXXXXXXXXXXXXXXDISPPTSIVVPLILKYLLFTMILVTLSVMATVLVLNIHWRSPDTHKMAPWVRSVFTSTLPKLL 1202
            LF  +FI            DA+RLYDDL+    Y+  +RPV + +  + + M L L Q++DV+ KNQI+  N+WV QEWND    W+P+DYG V  L++PS  IW PD+VLYNNA G++++  +  TK I++H G V+WKPP I+KS C I+VE+FPFD+Q C +K G+WT++G+++DLRH  Q   S    DN    I+  IDL  Y  +VEWD++ V A RN +FY CC EPYLDI FN++LRR+TLFY +NLI PC+ ISFL++LVFYLP+DSGEK+SL ISILLSLTVFFLL+ +I PPTS+ VPL+ KYLLFTM+LVTLSV+ T+ VLN+++RSP TH+MAPWV+ +F   LPKLL
Sbjct:    5 LFAAVFIALHFATGGLANPDAKRLYDDLLSN--YNRLIRPVGNNSDRLTVKMGLRLSQLIDVNLKNQIMTTNVWVEQEWNDYKLKWNPDDYGGVDTLHVPSEHIWLPDIVLYNNADGNYEV--TIMTKAILHHTGKVVWKPPAIYKSFCEIDVEYFPFDEQTCFMKFGSWTYDGYMVDLRHLKQTADS----DN----IEVGIDLQDYYISVEWDIMRVPAVRNEKFYSCCEEPYLDIVFNLTLRRKTLFYTVNLIIPCVGISFLSVLVFYLPSDSGEKISLCISILLSLTVFFLLLAEIIPPTSLTVPLLGKYLLFTMMLVTLSVVVTIAVLNVNFRSPVTHRMAPWVQRLFIQILPKLL 353          

Query: 1347 EIELALEGVRRIVHHIKKENSYSAMRDDWKYVAVVLDRLFLWLFSIAAIIGMLGIFMQAPTLTDNAIPM 1553
            E+E  +EG R I  H+K ++ + ++ +DWKYVA+VLDR+FLW+F+IA ++G   I +QAP+L D + P+
Sbjct:  476 EMEKTIEGSRFIAQHVKNKDKFESVEEDWKYVAMVLDRMFLWIFAIACVVGTALIILQAPSLYDQSQPI 544          

Query:  204 MRRRGYDPSVRPVKSYTSTVLLYMNLSLVQILDVDEKNQIIVLNMWVNQEWNDPNFVWDPNDYGNVTELNIPSREIWTPDLVLYNNAGGDWDLASSSNTKVIVNHDGSVLWKPPIIFKSQCGINVEFFPFDKQLCDLKIGTWTHNGFLIDLRHTAQKNQSQ----ASFDNCNAKIDYAIDLSQYVNNVEWDLLEVSAKRNIEFYPCCTEPYLDISFNVSLRRRTLFYGINLICPCLAISFLTILVFYLPADSGEKXXXXXXXXXXXXXXXXXXXDISPPTSIVVPLILKYLLFTMILVTLSVMATVLVLNIHWRSPDTHKMAPWVRSVFTSTLPKLLFMKKPDQDYRDNETDDIPE----------TFHEDETDSN--IQDKWSTRRAAVSGDNVVNEIELALEGVRRIVHHIKKENSYSAMRDDWKYVAVVLDRLFLWLFSIAAIIGMLGIFMQAPTLTD 1538
            M R  Y  SVRPV +Y+  VLLYMNLSL QILDVDEKNQI+ LNMWV+Q+W+DPNFVW+P  YGN+TEL+IPS +IWTPDLVLYNNAGGDWDL SS+N KV V  DG++LW+PPIIFKSQC INVEFFPFD Q C LK+GTWTHNG+LIDLRH AQK ++      +FDNC A IDYAIDLSQ+V+NVEWD+LEV+AKRNIE Y CC EPYLD++F++++RR+TLFYG+NLICPCLAISFLTILVFYLP +SGEK+SLSI+ILLSLTVFFLLIFDI PPTS+VVPLILKYLLFTMILVTLSVMATV+VLN+HWRSPDT+ MAPWVR VF  TLPKLL MKKP+ + R  E   IP            F  DE D    ++++  +RR A++   ++NEIELALEGVR I  H+KKE+  + +RDDWKYVAVVLDRLF+WLFS AAIIG LGIFMQAP+L D
Sbjct:    1 MNRTNYRSSVRPVTNYSQPVLLYMNLSLTQILDVDEKNQIVTLNMWVSQQWHDPNFVWNPAHYGNITELHIPSEDIWTPDLVLYNNAGGDWDLGSSAN-KVNVLSDGTILWRPPIIFKSQCEINVEFFPFDTQNCTLKLGTWTHNGYLIDLRHVAQKEEADRNGWRNFDNCKAYIDYAIDLSQFVDNVEWDILEVAAKRNIEKYKCCPEPYLDLTFSLNIRRKTLFYGVNLICPCLAISFLTILVFYLPGESGEKMSLSINILLSLTVFFLLIFDICPPTSLVVPLILKYLLFTMILVTLSVMATVIVLNVHWRSPDTYVMAPWVRQVFMRTLPKLLLMKKPETERRKEEV--IPNIGGTDTEALCAFLADEFDDGEVMRERLRSRRTAMTSSGIINEIELALEGVRNIATHMKKEDERNTIRDDWKYVAVVLDRLFMWLFSCAAIIGALGIFMQAPSLRD 458          

Query:  204 MRRRGYDPSVRPVKSYTSTVLLYMNLSLVQILDVDEKNQIIVLNMWVNQEWNDPNFVWDPNDYGNVTELNIPSREIWTPDLVLYNNAGGDWDLASSSNTKVIVNHDGSVLWKPPIIFKSQCGINVEFFPFDKQLCDLKIGTWTHNGFLIDLRHTAQKNQSQAS----FDNCNAKIDYAIDLSQYVNNVEWDLLEVSAKRNIEFYPCCTEPYLDISFNVSLRRRTLFYGINLICPCLAISFLTILVFYLPADSGEKXXXXXXXXXXXXXXXXXXXDISPPTSIVVPLILKYLLFTMILVTLSVMATVLVLNIHWRSPDTHKMAPWVRSVFTSTLPKLLFMKKPDQDYRDNETDDIPE----------TFHEDETDSN--IQDKWSTRRAAVSGDNVVNEIELALEGVRRIVHHIKKENSYSAMRDDWKYVAVVLDRLFLWLFSIAAII 1496
            M R  Y  SVRPV +Y+  VLLYMNLSL QILDVDEKNQI+ LNMWV+Q+W+DPNFVW+P  YGN+TEL+IPS +IWTPDLVL   AGGDWDL SS+N KV V  DG++LW+PPIIFKSQC INVEFFPFD Q C LK+GTWTHNG+LIDLRH AQK ++  +    FDNC A IDYAIDLSQ+V+NVEWD+LEV+AKRNIE Y CC EPYLD++F++++RR+TLFYG+NLICPCLAISFLTILVFYLP +SGEK+SLSI+ILLSLTVFFLLIFDI PPTS+VVPLILKYLLFTMILVTLSVMATV+VLN+HWRSPDT+ MAPWVR VF  TLPKLL MKKP+ + R  E   IP            F  DE D    ++++  +RR A++   ++NEIELALEGVR I  H+KKE+  + +RDDWKYVAVVLDRLF+WLFS AAII
Sbjct:    1 MNRTNYRSSVRPVTNYSQPVLLYMNLSLTQILDVDEKNQIVTLNMWVSQQWHDPNFVWNPAHYGNITELHIPSEDIWTPDLVLLQYAGGDWDLGSSAN-KVNVLSDGTILWRPPIIFKSQCEINVEFFPFDTQNCTLKLGTWTHNGYLIDLRHVAQKEEADRNGWRNFDNCKAYIDYAIDLSQFVDNVEWDILEVAAKRNIEKYKCCPEPYLDLTFSLNIRRKTLFYGVNLICPCLAISFLTILVFYLPGESGEKMSLSINILLSLTVFFLLIFDICPPTSLVVPLILKYLLFTMILVTLSVMATVIVLNVHWRSPDTYVMAPWVRQVFMRTLPKLLLMKKPETERRKEEV--IPNIGGTDTEALCAFLADEFDDGEVMRERLRSRRTAMTSSGIINEIELALEGVRNIATHMKKEDERNTIRDDWKYVAVVLDRLFMWLFSCAAII 444          

Query:   90 FVLIQFELIFTMICLGFLFGLIFIVQGTKDARRLYDDLMRRRGYDPSVRPVKSYTSTVLLYMNLSLVQILDVDEKNQIIVLNMWVNQEWNDPNFVWDPNDYGNVTELNIPSREIWTPDLVLYNNAGGDWDLASSSNTKVIVNHDGSVLWKPPIIFKSQCGINVEFFPFDKQLCDLKIGTWTHNGFLIDLRHTAQKNQSQASFDNCNAKIDYAIDLSQYVNNVEWDLLEVSAKRNIEFYPCCTEPYLDISFNVSLRRRTLFYGINLICPCLAISFLTILVFYLPADSGEKXXXXXXXXXXXXXXXXXXXDISPPTSIVVPLILKYLLFTMILVTLSVMATVLVLNIHWRSPDTHKMAPWVRSVFTSTLPKLLFMKKPDQ--DYRDNETDDIPETFHEDETDSNIQDKWSTRRAAVSGDNVVNEIELALEGVRRIVHHIKKENSYSAMRDDWKYVAVVLDRLFLWLFSIAAIIGMLGIFMQAPTLTDNAIPMTADNCPSVSSINVTKLTCETK 1616
             VLI + L F + C+  +   +     +    +LY  L  ++ Y P VRPV  + S VLL+MNLSL+QILDVDEK QII +N WVN +W D NF+WDP D+GNVT L +PS++IWTPDL LYNNAGGDWDLASSS+TKVIV++DG+V+W+PPIIFKSQCGINVE+FPFD Q C +KIG WTH+G LIDLRHT+QK  SQ +FDNC ++ID+AIDLS +  +V+WDL+ VSA+RNIEFYPCC+EPYLDI+F + LRR+ LF+G+NLICPC++IS LTILVFYLPADS EK+SLSIS L++LTVFFLL+F+ISPPTS+VVPLI+K+LLFTM+L+  S +ATV+VLNIH R+PDTHK++PW R +F   LPK+L +K+ +     +       P + +   +D  + D        +S    +++IE +L+ VR  V H +++   + +R +W+YVA V+DRL LW+F+ A + G++ IFMQAPTL      +TA   PSV +INVT+L+CETK
Sbjct:   12 LVLIFYALFFNVSCIKIVNSELL---PSGSDWKLYKYLTTKKNYSPFVRPVTRHESAVLLFMNLSLIQILDVDEKRQIIKMNAWVNLDWKDHNFMWDPKDHGNVTSLILPSQDIWTPDLALYNNAGGDWDLASSSSTKVIVHYDGTVIWRPPIIFKSQCGINVEYFPFDMQNCSMKIGCWTHHGLLIDLRHTSQKANSQPTFDNCRSQIDHAIDLSMFTTDVQWDLIGVSARRNIEFYPCCSEPYLDITFYIILRRKPLFFGVNLICPCISISILTILVFYLPADSREKISLSISTLIALTVFFLLVFEISPPTSLVVPLIVKFLLFTMVLIIFSTIATVIVLNIHTRTPDTHKISPWTRHIFIEVLPKVLRIKRYEHPGSKQIGRLSRSPPSLYVQNSDCVLTDFNQHMMEGLS----IDQIEASLDKVRHTVLHFRQQEKRNKIRSEWRYVAFVIDRLLLWMFAGATMAGIVSIFMQAPTLHTKERALTALTAPSVDAINVTRLSCETK 515          

Query:  186 RLYDDLMRRRGYDPSVRPVKSYTSTVLLYMNLSLVQILDVDEKNQIIVLNMWVNQEWNDPNFVWDPNDYGNVTELNIPSREIWTPDLVLYNNAGGDWDLASSSNTKVIVNHDGSVLWKPPIIFKSQCGINVEFFPFDKQLCDLKIGTWTHNGFLIDLRHTAQKNQSQASFDNCNAKIDYAIDLSQYVNNVEWDLLEVSAKRNIEFYPCCTEPYLDISFNVSLRRRTLFYGINLICPCLAISFLTILVFYLPADSGEKXXXXXXXXXXXXXXXXXXXDISPPTSIVVPLILKYLLFTMILVTLSVMATVLVLNIHWRSPDTHKMAPWVRSVFTSTLPKLLFMKKPDQ--DYRDNETDDIPETFHEDETDSNIQDKWSTRRAAVSGDNVVNEIELALEGVRRIVHHIKKENSYSAMRDDWKYVAVVLDRLFLWLFSIAAIIGMLGIFMQAPTLTDNAIPMTADNCPSVSSINVTKLTCETK 1616
            +LY  L  ++ Y P VRPV  + S VLL+MNLSL+QILDVDEK QII +N WVN +W D NF+WDP D+GNVT L +PS++IWTPDL LYNNAGGDWDLASSS+TKVIV++DG+V+W+PPIIFKSQCGINVE+FPFD Q C +KIG WTH+G LIDLRHT+QK  SQ +FDNC ++ID+AIDLS +  +V+WDL+ VSA+RNIEFYPCC+EPYLDI+F + LRR+ LF+G+NLICPC++IS LTILVFYLPADS EK+SLSIS L++LTVFFLL+F+ISPPTS+VVPLI+K+LLFTM+L+  S +ATV+VLNIH R+PDTHK++PW R +F   LPK+L +K+ +     +       P + +   +D  + D        +S    +++IE +L+ VR  V H +++   + +R +W+YVA V+DRL LW+F+ A + G++ IFMQAPTL      +TA   PSV +INVT+L+CETK
Sbjct:   26 KLYKYLTTKKNYSPFVRPVTRHESAVLLFMNLSLIQILDVDEKRQIIKMNAWVNLDWKDHNFMWDPKDHGNVTSLILPSQDIWTPDLALYNNAGGDWDLASSSSTKVIVHYDGTVIWRPPIIFKSQCGINVEYFPFDMQNCSMKIGCWTHHGLLIDLRHTSQKANSQPTFDNCRSQIDHAIDLSMFTTDVQWDLIGVSARRNIEFYPCCSEPYLDITFYIILRRKPLFFGVNLICPCISISILTILVFYLPADSREKISLSISTLIALTVFFLLVFEISPPTSLVVPLIVKFLLFTMVLIIFSTIATVIVLNIHTRTPDTHKISPWTRHIFIEVLPKVLRIKRYEHPGSKQIGRLSRSPPSLYVQNSDCVLTDFNQHMMEGLS----IDQIEASLDKVRHTVLHFRQQEKRNKIRSEWRYVAFVIDRLLLWMFAGATMAGIVSIFMQAPTLHTKERALTALTAPSVDAINVTRLSCETK 500          

Query:  123 MICLGFLFGLIFIVQGTKDARRLYDDLMRRRGYDPSVRPVKSYTSTVLLYMNLSLVQILDVDEKNQIIVLNMWVNQEWNDPNFVWDPNDYGNVTELNIPSREIWTPDLVLYNNAGGDWDLASSSNTKVIVNHDGSVLWKPPIIFKSQCGINVEFFPFDKQLCDLKIGTWTHNGFLIDLRHTAQKNQS----QASFDNCNAKIDYAIDLSQYVNNVEWDLLEVSAKRNIEFYPCCTEPYLDISFNVSLRRRTLFYGINLICPCLAISFLTILVFYLPADSGEKXXXXXXXXXXXXXXXXXXXDISPPTSIVVPLILKYLLFTMILVTLSVMATVLVLNIHWRSPDTHKMAPWVRSVFTSTLPKLLFMKKPDQDYRDNET------DDIPETFH--------------EDETDSN--IQDKWSTRRAAVSGDN-VVNEIELALEGV------RRIVHHIKKENSYSAMRDD 1430
            ++CL     L   V G + A++L+ DLM R  Y  SVRPV +Y+  VLLYMNLSL QILDVDEKNQI+ LNMWV+Q+W DPNFVW+ ++YGN++EL+IPS +IWTPDLVLYNNAGGDWDL SS+N KV V  DG++LW+PPIIFKSQC INVEFFPFD Q C LK+GTWTHNG+LIDLRH AQK ++    + SFD+C A IDYAIDLSQ+V+NVEWD+LEV+AKRNIE Y CC EPYLD++F + +RR+TLFYGINLICPCLAISFLTILVFYLP +SGEK+SLSI+ILLSLTVFFLLIFDI PPTS+VVPLILKYLLFTMILVTLSVMATV+VLN+HWRSPDT+ M+PWVR VF  TLPKLL MKKP+ + R  E       DD    F+              EDE      ++ +  +RR A++G + V+NEIELALEG       +  + H+  +N    ++ D
Sbjct:   14 LLCLLVAIHLPVEVSGIEGAKKLFKDLMNRTNYRASVRPVTNYSQPVLLYMNLSLTQILDVDEKNQIVTLNMWVSQQWFDPNFVWNESNYGNISELHIPSEDIWTPDLVLYNNAGGDWDLGSSAN-KVNVLSDGTILWRPPIIFKSQCEINVEFFPFDTQNCTLKLGTWTHNGYLIDLRHVAQKEEADRNGRQSFDDCRAVIDYAIDLSQFVDNVEWDILEVTAKRNIETYKCCPEPYLDLTFYLIIRRKTLFYGINLICPCLAISFLTILVFYLPGESGEKMSLSINILLSLTVFFLLIFDICPPTSLVVPLILKYLLFTMILVTLSVMATVVVLNVHWRSPDTYVMSPWVRQVFMRTLPKLLLMKKPETERRKEEVIPNFGGDDSERLFNFAAPGEAGISSADAEDEEAGQEVMRQRLRSRRTAMTGSSGVINEIELALEGAPSLRDNKERMTHLNTQNKMPTIKRD 481          

Query:  195 DDLMRR--RGYDPSVRPVKSYTSTVLLYMNLSLVQILDVDEKNQIIVLNMWVNQEWNDPNFVWDPNDYGNVTELNIPSREIWTPDLVLYNNAGGDWDLASSSNTKVIVNHDGSVLWKPPIIFKSQCGINVEFFPFDKQLCDLKIGTWTHNGFLIDLRHTAQKNQSQASFDNCNAKIDYAIDLSQYVNNVEWDLLEVSAKRNIEFYPCCTEPYLDISFNVSLRRRTLFYGINLICPCLAISFLTILVFYLPADSGEKXXXXXXXXXXXXXXXXXXXDISPPTSIVVPLILKYLLFTMILVTLSVMATVLVLNIHWRSPDTHKMAPWVRSVFTSTLPKLLFMKK--PDQDYR---------------------------DNETD---------------DIPETF--------HEDETDSNIQDKWSTRRAA---------VSGDNVVNEIEL--------ALEGVRRIVHHIKKENSYSAMRDDWKYVAVVLDRLFLWLFSIAAIIGMLGIFM 1517
            D L ++   GY+   RPV++ T  V++   LS+ Q++DVDEKNQ++  N+W+ QEWND    W P+DY NVT + +PS  IW PD+VLYNNA G  + A +  TK  + H G VLW PP I+KS C I+V FFPFD+Q C +K G+WT++   IDL                  +I+  +DL  Y  + EW ++      N + Y CC E Y DI++   +RR  LFY INLI PCL IS LT+LVFYLP+D GEK++L IS+LLSLTVF LLI +I P TS+V+PLI +YLLFTMI VTLS++ TV VLN+H RSP THKM  WV+S+F   +P+ LFMK+  PDQ  R                             ETD                IP +F        H  E++  +Q  +  ++           V+  N+  E  L        ALEGV+ I  H++ E++  ++++DWKYVA+V+DR+FLW+F I  ++G +G+F+
Sbjct:   24 DQLFKKLFSGYNKWSRPVRNITDVVIVKFGLSIAQLIDVDEKNQMMTTNVWLKQEWNDYKLRWKPSDYDNVTSIRVPSELIWVPDIVLYNNADG--EFAVTHMTKAHLFHTGKVLWVPPAIYKSSCSIDVTFFPFDQQNCKMKFGSWTYDKAKIDLE-----------------RIENTVDLKDYWESGEWAIVNAVGTYNTKKYDCCHEIYPDITYFFIIRRLPLFYTINLIIPCLLISCLTVLVFYLPSDCGEKITLCISVLLSLTVFLLLITEIIPSTSLVIPLIGEYLLFTMIFVTLSIVITVFVLNVHHRSPSTHKMPGWVQSIFLGFIPRWLFMKRPAPDQTRRRLLLNAQEKKQVPNQTSNLSTSRSSWLQQETDVDIGRYQDSNGRAGMGIPASFSFPTATSLHLSESEPLLQSLYDLQQLGHRINLNSRPVNLSNLEPEPRLPFSHSVMQALEGVQYIADHLRAEDADFSVKEDWKYVAMVIDRIFLWMFIIVCLLGTVGLFL 516          

Query:  171 TKDARRL------YDDLMRRR--GYDPSVRPVKSYTSTVLLYMNLSLVQILDVDEKNQIIVLNMWVNQEWNDPNFVWDPNDYGNVTELNIPSREIWTPDLVLYNNAGGDWDLASSSNTKVIVNHDGSVLWKPPIIFKSQCGINVEFFPFDKQLCDLKIGTWTHNGFLIDLRHTAQKNQSQASFDNCNAKIDYAIDLSQYVNNVEWDLLEVSAKRNIEFYPCCTEPYLDISFNVSLRRRTLFYGINLICPCLAISFLTILVFYLPADSGEKXXXXXXXXXXXXXXXXXXXDISPPTSIVVPLILKYLLFTMILVTLSVMATVLVLNIHWRSPDTHKMAPWVRSVFTSTLPKLLFMKKPDQDYRDNETDD--------IPETFHE----DETDSNIQDKWSTRRAAVSGDNVVNEIELALEGVRRIVHHIKKENSYSAMRDDWKYVAVVLDRLFLWLFSIAAIIGMLGIFM 1517
            TK AR L       D+L ++   GY+   RPV + +  V++   LS+ Q++DVDEKNQ++  N+W+ QEWND    W P+DY NVT + +PS  IW PD+VLYNNA G  + A +  TK  + + G V W PP I+KS C I+V FFPFD+Q C +K G+WT++   IDL                  +++  +DL  Y  + EW ++      N + Y CC E Y DI++   +RR  LFY INLI PCL IS LT+LVFYLP+D GEK++L IS+LLSLTVF LLI +I P TS+V+PLI +YLLFTMI VTLS++ TV VLN+H RSP TH+M  WV +VF   +P+ LFM++P  D R  +           +P + H     + T+   ++    +R+ +S       I  ALEGV  I  H++ E++  ++++DWKYVA+V+DR+FLW+F I  ++G +G+F+
Sbjct:   40 TKVARNLGTHSHAEDELFKKLFIGYNKWSRPVPNTSDVVIVKFGLSIAQLIDVDEKNQMMTTNVWLKQEWNDYKLRWKPSDYDNVTSIRVPSELIWVPDIVLYNNADG--EFAVTHMTKAHLFYTGKVRWVPPAIYKSSCSIDVTFFPFDQQNCKMKFGSWTYDKAKIDLE-----------------RLETMVDLKDYWESGEWAIINAVGTYNTKKYDCCHEIYPDITYFFIIRRLPLFYTINLIIPCLLISCLTVLVFYLPSDCGEKITLCISVLLSLTVFLLLITEIIPSTSLVIPLIGEYLLFTMIFVTLSIIITVFVLNVHHRSPGTHEMPHWVHAVFLDLIPRWLFMRRPAPDSRRRQRLLLLQQGMACLPNSRHSGARINHTNRPTEED---QRSPLSP-----SIMQALEGVHYIADHLRAEDADFSVKEDWKYVAMVIDRIFLWMFIIVCLLGTIGLFL 481          

Query:  168 GTKDARRLYDDLMRRRGYDPSVRPVKSYTSTVLLYMNLSLVQILDVDEKNQIIVLNMWVNQEWNDPNFVWDPNDYGNVTELNIPSREIWTPDLVLYNNAGGDWDLASSSNTKVIVNHDGSVLWKPPIIFKSQCGINVEFFPFDKQLCDLKIGTWTHNGFLIDLRHTAQKNQSQASFDNCNAKIDYAIDLSQYVNNVEWDLLEVSAKRNIEFYPCCTEPYLDISFNVSLRRRTLFYGINLICPCLAISFLTILVFYLPADSGEKXXXXXXXXXXXXXXXXXXXDISPPTSIVVPLILKYLLFTMILVTLSVMATVLVLNIHWRSPDTHKMAPWVRSVFTSTLPKLLFMKKPDQDYRDNETDDIPE---TFHEDETDSNIQDKWSTRRAAVSGDNVVNEIELALEGVRRIVHHIKKENSYSAMRDDWKYVAVVLDRLFLWLFSIAAIIGMLGIFMQAPTLTDN 1541
             ++   RL+  +     Y+  +RPV++ +  V++   +S+ Q++ VDE NQI+  N+W+   WND    WDP D+G V  + +PS  IW PD+VLYNNA GD+ +     TK ++ ++G V W PP IFKS C I+V +FPFD Q C +K G+WT++   IDL                   I   I+L  +  + EW +++    ++   Y CC E Y DI++++ +RR  LFY IN+I PCL ISFLT+LVFYLP+D GEKV+L IS+LLSLTVF L+I +  P TS+V+PLI +YLLFTMI VTLS++ TV VLN+H+R+P TH M  WVR VF   LP+++FM +PD+D    +         T H   +      K       ++   +  E+  A+E V+ I  +++ +N    ++DDWKYVA+V+DR+FLW+F +  I+G  G+F+Q   L ++
Sbjct:   21 ASEAEHRLFSVIFS--SYNQYIRPVENVSDPVIVQFEVSMSQLVKVDEVNQIMETNLWLRHIWNDYKLRWDPKDFGGVEFIRVPSNRIWKPDIVLYNNAVGDFQV--DDKTKALLRYNGDVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWTYDKAKIDL-----------------VLIGSTINLKDFWESGEWMIIDAPGYKHDIKYNCCEEIYTDITYSLYIRRLPLFYTINMIIPCLLISFLTVLVFYLPSDCGEKVTLCISVLLSLTVFLLVITETIPSTSLVIPLIGEYLLFTMIFVTLSIVITVFVLNVHYRTPKTHTMPCWVRRVFLGLLPRVMFMTRPDRDPERPQVSGSSARSCTLHNSSSFPQHLTKPLGPVRLLAFSALSPEVREAIESVKYIAENMRLQNEAKEVQDDWKYVAMVIDRIFLWVFILVCILGTAGLFLQPLLLVED 460          

Query:  219 YDPSVRPVKSYTSTVLLYMNLSLVQILDVDEKNQIIVLNMWVNQEWNDPNFVWDPNDYGNVTELNIPSREIWTPDLVLYNNAGGDWDLASSSNTKVIVNHDGSVLWKPPIIFKSQCGINVEFFPFDKQLCDLKIGTWTHNGFLIDLRHTAQKNQSQASFDNCNAKIDYAIDLSQYVNNVEWDLLEVSAKRNIEFYPCCTEPYLDISFNVSLRRRTLFYGINLICPCLAISFLTILVFYLPADSGEKXXXXXXXXXXXXXXXXXXXDISPPTSIVVPLILKYLLFTMILVTLSVMATVLVLNIHWRSPDTHKMAPWVRSVFTSTLPKLLFMKKP-DQDYRDNETDDIPETFHEDETDSNIQDKWSTRRAAVSGDNVVNEIELALEGVRRIVHHIKKENSYSAMRDDWKYVAVVLDRLFLWLFSIAAIIGMLGIFMQ 1520
            Y+  +RPV++ +  V +   +S+ Q++ VDE NQI+  N+W+   WND    W P ++  +  + +PS +IW PD+VLYNNA GD+ +     TK ++  DG++ W PP IFKS C +++ +FPFD Q C +K G+WT++   IDL     K                 ++L  +  + EW++++    ++   Y CC E Y DI+++  +RR  LFY INLI PCL ISFLT+LVFYLP+D GEKV+L IS+LLSLTVF L+I +  P TS+V+PLI +YLLFTMI VTLS++ TV VLN+H+R+P TH M  WVR+VF   LP+++ M++P DQ     +  + PE    D    + Q         V+   V  EI+ A+E V+ I  +++  N    + DDWKYVA+V+DR+FLW+F +  ++G +G+F Q
Sbjct:   28 YNQFIRPVENVSDPVTVEFEVSISQLVKVDEVNQIMETNLWLRHIWNDYKLKWIPAEFDGIEYIRVPSNKIWRPDIVLYNNAVGDFLV--EDKTKALLKFDGTITWVPPAIFKSSCPMDITYFPFDYQNCSMKFGSWTYDKAKIDLVLIGSK-----------------VNLKDFWESGEWEIIDAPGYKHDIKYNCCEEIYPDITYSFYIRRLPLFYTINLIIPCLLISFLTVLVFYLPSDCGEKVTLCISVLLSLTVFLLVITETIPSTSLVIPLIGEYLLFTMIFVTLSIVITVFVLNVHYRTPTTHTMPGWVRTVFLRALPRIMLMRRPIDQSESSTKAKEGPEV---DCGKVSRQLSPQAINTVVAFSVVSPEIKQAIESVKYIAENMRSRNKAKEVEDDWKYVAMVIDRIFLWVFVLVCVLGTVGLFFQ 440          

Query:  123 MICLGFLFGLIFIVQGTKDARRLYDDLMRR--RGYDPSVRPVKSYTSTVLLYMNLSLVQILDVDEKNQIIVLNMWVNQEWNDPNFVWDPNDYGNVTELNIPSREIWTPDLVLYNNAGGDWDLASSSNTKVIVNHDGSVLWKPPIIFKSQCGINVEFFPFDKQLCDLKIGTWTHNGFLIDLRHTAQKNQSQASFDNCNAKIDYAIDLSQYVNNVEWDLLEVSAKRNIEFYPCCTEPYLDISFNVSLRRRTLFYGINLICPCLAISFLTILVFYLPADSGEKXXXXXXXXXXXXXXXXXXXDISPPTSIVVPLILKYLLFTMILVTLSVMATVLVLNIHWRSPDT-HKMAPWVRSVFTSTLPKLLFMKKPDQDYRDNETDDIPETFHEDETDSNIQDKWSTRRAAVSGDNVVNE-----IELALEGVRRIVHHIKKENSYSAMRDDWKYVAVVLDRLFLWLFSIAAIIGMLGIFMQAPTLTDNAIP 1550
            ++C  F+F L    +       L D L+R   RGY   VRPV     T+ +   L + Q++DVDEKNQ++  N+W+ QEW D    WDP DYG +T + +PS  IW PD+VLY NA G ++   S  TK IV +DG++ W PP  +KS C ++V FFPFD+Q C +K G+WT++G ++DL                 A +D  +D   + +N EW++L+ + +R        + P++  SF   L+R  LFY + LI PCL +SFLT+LVFYLP+D GEK+SLS S+L+SLTVF L+I +I P +S V+PLI +YLLF MI VT S++ TV V+N+H RS  T H MAPWV+S+F   LP+LL M      YR  + +      H  E    ++         V      N+     +E A   VR I  HIKKE+    +  DWK+VA VLDR+FLW F   +++G + IF  A  +  +  P
Sbjct:   10 LLCF-FMFSLSPAPEEYVSLAELEDTLLRNVFRGYQKWVRPVFHANDTIAVRFGLKISQLVDVDEKNQLMTTNVWLWQEWTDYKLRWDPEDYGGITSIRVPSENIWLPDIVLYENADGRFE--GSLMTKAIVKYDGTITWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGTMVDL-----------------ALVDQHVDRKDFFDNGEWEILDATGRRGSRRDGIYSYPFVTYSF--ILKRLPLFYTLFLIIPCLGLSFLTVLVFYLPSDEGEKLSLSTSVLVSLTVFLLVIEEIIPSSSKVIPLIGEYLLFIMIFVTFSIIVTVFVINVHHRSSATYHPMAPWVKSLFLQRLPRLLCMHGHTDRYRYPDME-----LHSPELKRGMKRGQQRSACGVGVKEEENQAWMSMLEKATSSVRYISRHIKKEHFIREVVQDWKFVAQVLDRIFLWAFLTVSVLGTILIFTPALKMYLSTAP 466          

Query:  165 QGTKDARRLYDDLMRRRGYDPSVRPVKSYTSTVLLYMNLSLVQILDVDEKNQIIVLNMWVNQEWNDPNFVWDPNDYGNVTELNIPSREIWTPDLVLYNNAGGDWDLASSSNTKVIVNHDGSVLWKPPIIFKSQCGINVEFFPFDKQLCDLKIGTWTHNGFLIDLRHTAQKNQSQASFDNCNAKIDYAIDLSQYVNNVEWDLLEVSAKRNIEFYPCCTEPYLDISFNVSLRRRTLFYGINLICPCLAISFLTILVFYLPADSGEKXXXXXXXXXXXXXXXXXXXDISPPTSIVVPLILKYLLFTMILVTLSVMATVLVLNIHWRSPDTHKMAPWVRSVFTSTLPKLLFMKKP--------DQDYRDNETDDIPETFHEDE------------TDSNIQDKWSTRRAAVSGDNVVN-------------------------------EIELALEGVRRIVHHIKKENSYSAMRDDWKYVAVVLDRLFLWLFSIAAIIGMLGIFMQ 1520
            + ++ A RLY  L     Y+P +RPV + +  V++   +S+ Q++ +DE NQI+  N+W+   WND  F W+P  +  +  + +PS +IW PD+VLYNNA GD+ +     TK ++ +DG+V+W PP IFKS C I+V +FPFD Q C +K G+WT++   IDL     K                 I+L  +  + EW +++V   ++   Y CC + Y DI+++V +RR  LFY INLI PCL ISFLT+LVFYLP+D GEKV+LSIS+LLSLTVF L+I +  P TS+V+PLI +YLLFTMI VTLS++ T+ VLN+H+R+P+ H M  WVR VF  TLPK++ ++ P          D   +E D  P      E                I    S+  A VS   +                                 EI   ++ V+ I  +++ ++    + DDWKYVA+V+DR+FLW+F +  I+G  G+F+Q
Sbjct:    3 RASEAASRLYKTLFT--SYNPYIRPVFNVSDPVIVRFEVSMSQLVKLDEVNQIMATNLWLKHTWNDYKFQWNPGQFEGMEYIRVPSDKIWKPDIVLYNNADGDFQV--EGKTKALLKYDGTVMWMPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWTYDKAKIDLVLVGTK-----------------INLKDFWESGEWVIIDVPGYKHDIKYNCCEQIYPDITYSVYVRRLPLFYTINLIIPCLLISFLTVLVFYLPSDCGEKVTLSISVLLSLTVFLLVITETIPSTSLVIPLIGEYLLFTMIFVTLSIVITIFVLNVHYRTPEAHTMPNWVRRVFLDTLPKIMLLQPPKGSVGTAASPDAVVSEADQQPACLCAGELSAAAASSSSSCQSGGISRASSSMEAHVSSVRLPRLRAADVMSDELSSSSSTESLDALLALCLLSPEIRQVIDSVKYIAENLRTQDEAKEVCDDWKYVAMVVDRIFLWVFVLVCILGTAGLFLQ 484          

Query:  186 RLYDDLMRR--RGYDPSVRPVKSYTSTVLLYMNLSLVQILDVDEKNQIIVLNMWVNQEWNDPNFVWDPNDYGNVTELNIPSREIWTPDLVLYNNAGGDWDLASSSNTKVIVNHDGSVLWKPPIIFKSQCGINVEFFPFDKQLCDLKIGTWTHNGFLIDLRHTAQKNQSQASFDNCNAKIDYAIDLSQYVNNVEWDLLEVSAKRNIEFYPCCTEPYLDISFNVSLRRRTLFYGINLICPCLAISFLTILVFYLPADSGEKXXXXXXXXXXXXXXXXXXXDISPPTSIVVPLILKYLLFTMILVTLSVMATVLVLNIHWRSPDTHK-MAPWVRSVFTSTLPKLLFMKK-------PDQDYRDNETDDIPETFHEDETDSNIQDKWSTRRAAVSGDNVVNEIELALEGVRRIVHHIKKENSYSAMRDDWKYVAVVLDRLFLWLFSIAAIIGMLGIFMQAPTL 1532
             L D L++R  + Y   VRPV   + TV +   L + Q++DVDEKNQ++  N+W+ QEW D N  W+P+DYG +  + +P+  IW PD+VLY+NA G ++   S  TK +V HDG + W PP I+KS C I+V FFPFD+Q C +K G+WT++G L+DL                   ++  +D  +Y +N EW+ L  +  + +        PY+  SF +  RR  LFY + LI PCL +SFLT+ VFYLP+D GEK+SL  S+L+SLTVF L+I +I P +S V+PLI +YLLF MI VTLS++ TV V+N+H RS  TH  MAPWVR +F   LPK+L M+        PD+  RD+         H  E+  +  ++                I  A++ VR I  HIKKEN    + +DWK+VA V+DR+ LW F   ++ G + IF+  PT+
Sbjct:   33 ELEDRLLKRMLKDYQKWVRPVDKLSDTVEVKFGLGIAQLVDVDEKNQLMTTNVWLKQEWVDINLRWNPDDYGGINSIRVPASSIWLPDIVLYDNADGRFE--GSIVTKAVVKHDGRIKWTPPAIYKSSCTIDVTFFPFDQQNCSMKFGSWTYDGTLVDL-----------------IMVNSDVDRGEYFDNGEWEFLNATGNKGVRLDGHRFYPYITYSFVI--RRLPLFYTLFLIVPCLGLSFLTVFVFYLPSDEGEKISLCTSVLVSLTVFLLVIEEIIPSSSKVIPLIGEYLLFIMIFVTLSIIITVFVINVHHRSSSTHHPMAPWVRQLFLHKLPKILCMRSHVDRYTAPDEADRDHP-GRAGCACHGGESPPSASERL---------------ILTAIDSVRYITRHIKKENEVREVVEDWKFVAQVVDRILLWTFLSVSVFGSILIFL--PTI 452          

Query:  291 QILDVDEKNQIIVLNMWVNQEWNDPNFVWDPNDYGNVTELNIPSREIWTPDLVLYNNAGGDWDLASSSNTKVIVNHDGSVLWKPPIIFKSQCGINVEFFPFDKQLCDLKIGTWTHNGFLIDLRHTAQKNQSQASFDNCNAKIDYAIDLSQYVNNVEWDLLEVSAKRNIEFYPCCTEPYLDISFNVSLRRRTLFYGINLICPCLAISFLTILVFYLPADSGEKXXXXXXXXXXXXXXXXXXXDISPPTSIVVPLILKYLLFTMILVTLSVMATVLVLNIHWRSPDTHKMAPWVRSVFTSTLPKLLFMKKPDQDYRDNE 1241
             + D DEKNQ++  N+W+ QEW+D    WDP +Y NVT + +PS  IW PD+VLYNNA GD   A +  TK  + H G V WKPP I+KS C I+V FFPFD+Q C +K G+WT++   IDL   A+                  +DL  Y  + EW ++      N + Y CC + Y DI+++  +RR  LFY INLI PCL IS LT+LVFYLP+D GEK++L IS+LLSLTVF LLI +I P TS+V+PLI +YLLFTMI VTLS++ TV VLN+H RSP TH M  WVR VF   +P+ L M++P    R +E
Sbjct:    9 HLCDCDEKNQMMTTNVWLKQEWDDYKLQWDPAEYENVTSIRVPSELIWVPDIVLYNNADGD--FAVTHMTKAHLFHTGRVRWKPPAIYKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDLVSMARD-----------------VDLKDYWESGEWAIVHAVGTYNTKKYDCCPQVYPDITYSFIIRRLPLFYTINLIIPCLLISCLTVLVFYLPSDCGEKITLCISVLLSLTVFLLLITEIIPSTSLVIPLIGEYLLFTMIFVTLSIVITVFVLNVHHRSPATHAMPRWVRRVFLDRVPRWLVMRRPPPQQRRSE 306          

Query: 1362 LEGVRRIVHHIKKENSYSAMRDDWKYVAVVLDRLFLWLFSIAAIIGMLGIFM 1517
            ++GV+ I +H++ E+++ ++++DWKYVA+V+DR+FLW+F +  ++G +G+F+
Sbjct:  507 VQGVQYIANHLRAEDAHLSVKEDWKYVAMVIDRIFLWVFIVVCLLGTVGLFL 558          

Query:  162 VQGTKDARRLYDDLMRRRGYDPSVRPVKSYTSTVLLYMNLSLVQILDVDEKNQIIVLNMWVNQEWNDPNFVWDPNDYGNVTELNIPSREIWTPDLVLYNNAGGDWDLASSSNTKVIVNHDGSVLWKPPIIFKSQCGINVEFFPFDKQLCDLKIGTWTHNGFLIDLRHTAQKNQSQASFDNCNAKIDYAIDLSQYVNNVEWDLLEVSAKRNIEFYPCCTEP----YLDISFNVSLRRRTLFYGINLICPCLAISFLTILVFYLPADSGEKXXXXXXXXXXXXXXXXXXXDISPPTSIVVPLILKYLLFTMILVTLSVMATVLVLNIHWRSPDTHKMAPWVRSVFTSTLPKLLFMKKPDQDYRDNETDDIPETFHEDE--------------------TDSNIQDKWSTRRAAVSGDNVV--NEIELALEGVRRIVHHIKKENSYSAMRDDWKYVAVVLDRLFLWLFSIAAIIGMLGIFMQA 1523
            V+G +    L  DL   + Y   VRP ++ T  V + + ++L Q++ +      + L+  ++  W DP   WDP +Y N+  + +  + +W PD+ L NN  G++D        V+V++ G+V W PP I++S CG+ V++FPFD Q C +   ++T++   I+L +   +++ +             ID S +  + EW +    +++N       T P    Y DI+F + + R+ LFY IN++ PC+ I+   +  FYLP D+GEK+ L IS+LL+LTVF LL+ D  P TS+ VP+I+ YL+FTM++VT  V+ TV+VLN+H+RSP TH M  WVR +F  +LPK L++++P ++    +   +  T H+                      + S     +S+  A     +VV   E++ A++ V  I  H+  +  +  +++DW+YVA+V+DR+F   F +   +G  GIF  A
Sbjct:   18 VRGLEAEENLLKDLFVVQQYKTLVRPARTATGRVTVRLGMTLSQLISLPACQPDMTLSRLISLSWEDPRLSWDPRNYDNLRSIRLSPKRVWLPDIALSNNNDGNFDFGLY--VHVLVDYTGAVRWVPPSIYRSSCGMQVKYFPFDWQNCSMVFQSFTYDTSEINLEYALDEHRQEIR--------HIIIDESTFPVSGEWQIKHKPSRKN-------TNPRDPLYQDITFYLIMERKPLFYIINIVVPCILITICAVFTFYLPPDAGEKMGLCISVLLALTVFLLLLADKVPETSLGVPVIVNYLMFTMVIVTACVILTVIVLNLHFRSPATHIMPYWVRRIFIHSLPKYLWIERPKKEELAPKLPVL--TQHQQHCHDEYFIRTPPSQALLLLPTSPSFGMTPFSSELAGPDKLHVVLPPELQSAVDAVHYISEHMLSQKEFDELKEDWQYVAMVVDRIFFITFFLITSLGTFGIFFNA 478          

Query:  387 DYGNVTELNIPSREIWTPDLVLYNNAGGDWDLASSSNTKVIVNHDGSVLWKPPIIFKSQCGINVEFFPFDKQLCDLKIGTWTHNGFLIDLRHTAQKNQSQASFDNCNAKIDYAIDLSQYVNNVEWDLLEVSAKRNIEFYPCCTEPYLDISFNVSLRRRTLFYGINLICPCLAISFLTILVFYLPADSGEKXXXXXXXXXXXXXXXXXXXDISPPTSIVVPLILKYLLFTMILVTLSVMATVLVLNIHWRSPDTHKMAPWVRSVFTSTLPKLLFMKKPDQDYRD 1235
            ++  V  L     +IWTPD++LYN+A   +D  ++ +T V+VN+ G+    PP + KS C I+V +FPFD Q CDLK G+WTH+G+LIDL+                       D S Y+ N EWDL+E+  KRN  +Y CC EPY D+++ +++RRRTL+YG+NL+ PC+ IS L++LVF LPADSGEK+SL I++LLSLTVF LL+ +I P TS  VPLI +Y   TMI+V  SV+ TV+VL  H  +PD  KM  WVR +        L MK+P ++  +
Sbjct:    2 EHPGVKNLRFQPHQIWTPDILLYNSADERFD--ATFHTNVLVNYTGNCQHLPPGMLKSTCYIDVRWFPFDVQKCDLKFGSWTHDGWLIDLQMLEA-------------------DTSGYIANGEWDLVEIPGKRNELYYDCCQEPYPDVTYTLTIRRRTLYYGLNLLVPCVLISALSLLVFLLPADSGEKISLGITVLLSLTVFMLLVAEIMPATSDSVPLIGQYFASTMIIVAFSVVVTVIVLQYHHHNPDGKKMPQWVRVILLDWCAWFLRMKQPGRERHE 263          

Query:  177 DARRLYDDLMRRRGYDPSVRPVKSYTSTVLLYMNLSLVQILDVDEKNQIIVLNMWVNQEWNDPNFVWDPNDYGNVTELNIPSREIWTPDLVLYNNAGGDWDLA-SSSNTKVIVNHDGSVLWKPPIIFKSQCGINVEFFPFDKQLCDLKIGTWTHNGFLIDLRHTAQKNQSQASFDNCNAKIDYAIDLSQYVNNVEWDLLEVSAKRNIEFYPCCTEPYLDISFNVSLRRRTLFYGINLICPCLAISFLTILVFYLPADSGEKXXXXXXXXXXXXXXXXXXXDISPPTSIVVPLILKYLLFTMILVTLSVMATVLVLNIHWRSPDTHKMAPWVRSVFTSTLPKLLFMKKPDQDYRDNETDDIP----------------------------------------------ETFHEDETDSNIQDKWSTRR------AAVSGDN-----VVNEIELALEGVRRIVHHIKKENSYSAMRDDWKYVAVVLDRLFLWLFSIAAIIGMLGIFMQ 1520
            D  RL  DL    GY+P +RPV      V + + +S+ QI+DV EK+QII  + WV Q W +P   W+   YG + E+N+   ++WTPDLVLYNNA    D +  +  T++IV+ DG  +W  P+IF S C I +++FPFD Q C LK G+WT +GF +DL+  A     QAS             LS+++ N EWDL+   A RN+  Y CC  PY D++F + LRRR LF+  NLI PC  I  LT L FYLP DSGE++S+ I+ LL++TVF L++ DI PPTS  V +I  +   ++I V ++++ T +VL  H+ S   HKM PWVR +    L K+   ++   D  D+++D I                                                   +DE        +S+ R      AA +  N     +++  E  ++ +  + H  + ++     +++WK  A +LD  F WLF ++  I  + ++++
Sbjct:   49 DEGRLTRDLFA--GYNPKLRPVFHKRENVTVVLGMSVHQIIDVYEKDQIIKTSFWVRQIWYNPFLRWNETFYGGIKEINVSPLQVWTPDLVLYNNADASTDGSLENFKTRIIVSSDGKNMWLAPVIFSSSCTIKIKYFPFDDQYCSLKFGSWTFDGFHLDLKPEA----PQAS-------------LSKFIPNGEWDLIGAPAIRNVLRYDCCPAPYPDVTFTLHLRRRVLFFLFNLIIPCFVIVVLTSLSFYLPPDSGERISVVITNLLAMTVFMLMVADILPPTSDEVSIISIFYSCSIIEVGIALLGTCIVLKYHFCSTSIHKMPPWVRFLVIECLGKVFCRQEHTNDQEDSKSDTIKLDNCKHKLENGLKDPLIKQCNFFGKFGVRERVRSSGMKTTDGGSNLSMTQDDEGRGRGGTPYSSHRNMDDIIAAEASSNSTVFALLSRQESMVKNLEILAHAQRCQDEEDREKNEWKLAASILDNFFCWLFLMSIFISSIVLYVR 535          

Query:  183 RRLYDDLMRRRGYDPSVRPVKSYTSTVLLYMNLSLVQILDVDEKNQIIVLNMWVNQEWNDPNFVWDPNDYGNVTELNIPSREIWTPDLVLYNNAGGDWDLA-SSSNTKVIVNHDGSVLWKPPIIFKSQCGINVEFFPFDKQLCDLKIGTWTHNGFLIDLRHTAQKNQSQASFDNCNAKIDYAIDLSQYVNNVEWDLLEVSAKRNIEFYPCCTEPYLDISFNVSLRRRTLFYGINLICPCLAISFLTILVFYLPADSGEKXXXXXXXXXXXXXXXXXXXDISPPTSIVVPLILKYLLFTMILVTLSVMATVLVLNIHWRSPDTHKMAPWVRSVFTSTLPKLLFMKKPDQDYRDNETDD-IPETFHEDETDSNIQDKWSTRRAAVSGDNVVNEIELALEGVRRIVHHIKKENSYSAMRDDWKYVAVVLDRLFLWLFSIAAIIGMLGIFMQAPTL 1532
            +RL  DL R   YD  VRPV + +  V +  +LSL+QI+ V+ K+Q++ +++W+ Q+W +P   W+ + YG +  +N+   ++W PD++LYNNA   +        T VI + DG+  W  P  F S C INV +FPFD Q C LK G+WT+ G  + +  T+                  + DLS+YVNN EW LL + AK N  FY CC  P+ D++  + ++R+ L+Y  NLI PC  I+ LT++ F+LP +SGEKV L I++LL++TVF LL+ +  P TS  +PL+ +Y + TM +  +S++AT L+LN   R+P T  M  WV+ +       L +M +  ++ R    D  IP +      +         RR +     +    E  L+ +  +   ++       +R++W+  A+VLDR+F W+  + +++    IF + P +
Sbjct:   39 KRLLADLFR--NYDSEVRPVFNDSDKVNVEFSLSLIQIIAVNSKSQLVTVSVWIRQKWTNPMLAWNTSKYGGIESVNLNPAKVWIPDIILYNNADETYAGGLEKYKTSVIASSDGTQEWNSPASFTSTCNINVRYFPFDSQNCSLKFGSWTYVGNRLTMTSTSD-----------------SADLSKYVNNGEWHLLAMPAKLNRVFYNCCKYPFYDVTLYLEIQRKPLYYVFNLIIPCALIATLTLIKFFLPPESGEKVGLGITVLLAMTVFLLLVAETLPSTSDHIPLLGQYFVATMFVTAISLVATCLILNFFHRNPSTSPMPHWVKVII------LDYMARSPRNARLMRDDSVIPPSGRSTPCER--------RRMSTVSSQLNPFTERLLDDINVLAEDVRARQEDERLREEWRCAALVLDRMFFWIMLVTSLMTSFMIFYRDPVM 457          

Query:  186 RLYDDLMRRRGYDPSVRPVKSYTSTVLLYMNLSLVQILDVDEKNQIIVLNMWVNQEWNDPNFVWDPNDYGNVTELNIPSREIWTPDLVLYNNAGGDWDLA-SSSNTKVIVNHDGSVLWKPPIIFKSQCGINVEFFPFDKQLCDLKIGTWTHNGFLIDLRHTAQKNQSQASFDNCNAKIDYAIDLSQYVNNVEWDLLEVSAKRNIEFYPCCTEPYLDISFNVSLRRRTLFYGINLICPCLAISFLTILVFYLPADSGEKXXXXXXXXXXXXXXXXXXXDISPPTSIVVPLILKYLLFTMILVTL 1091
            +L  DL     Y+PSVRPV   TS+V + + +SL QI+D+DE+NQI++ N+WV Q+WN+P   WDP  +GN+T +N+    +W PDL+LYNNA  D D A     TKV +  DGS LW  PIIFKS C  +V +FPFD+Q C LK G+WT++G  +++     +N +    D             ++V+N EW+L  VSA RN+ FY CC EPY D++F + +RR TLFY +N++ PC  I+ LT+L + LP +SGE+++L ++ LL+  V+ LL+ +I PP + VVPLI  Y    M +VT+
Sbjct:    4 KLLKDLFS--NYNPSVRPVLKATSSVTVQLGVSLHQIIDLDERNQILISNLWVRQKWNNPLLTWDPTHFGNLTSINVDPLRVWRPDLILYNNADRDTDGALDRFYTKVQLKFDGSSLWLAPIIFKSTCKFDVAYFPFDEQSCILKFGSWTYDGLRLNI---VPENGTDIGID-------------KFVSNGEWELTGVSANRNVMFYDCCVEPYPDVTFTLKIRRLTLFYYMNMLIPCFLITGLTLLSYILPPESGERITLVVTSLLAQAVYLLLVSEIMPPVAEVVPLISIYYTTAMFMVTV 288          

Query:  177 DARRLYDDLMRRRGYDPSVRPVKSYTSTVLLYMNLSLVQILDVDEKNQIIVLNMWVNQEWNDPNFVWDPNDYGNVTELNIPSREIWTPDLVLYNNAGGDWDLASSSNT-KVIVNHDGSVLWKPPIIFKSQCGINVEFFPFDKQLCDLKIGTWTHNGFLIDLRHTAQKNQSQASFDNCNAKIDYAIDLSQYVNNVEWDLLEVSAKRNIEFYPCCTE-PYLDISFNVSLRRRTLFYGINLICPCLAISFLTILVFYLPADSGEKXXXXXXXXXXXXXXXXXXXDISPPTSIVVPLILKYLLFTMILVTLSVMATVLVLNIHWRSPDTHKMAPWVRSVFTSTLPKLL---FMKKPDQDYRDNETDDIPETFHEDETDSNIQDKWS-----TRR--AAVSGD-----------------------NVVNEIELALEGVRRIVHHIKKENSYSAMRDDWKYVAVVLDRLFLWLFSIAAIIGMLGIFMQAPT 1529
            D RRL  D+     YD  +RPV S T  V + + L+L QI+DV EK +++ ++++V Q+W +P   W+ ++YG + ++N+    +W PD+ LYNNA   +D +    T K+ VN+ G+  W  P IF + C INV++FPFD+Q C LK G+WT++   +D+       + QAS             +  Y  N EWD +    KR+I +YPCC + P+ D++  + +RR+TL+Y +NLI PC+ I+ L++L F +  DSGE+V L I+ LL+LTVF L++ DI PPTS VVP+I  Y++ + I V L+++AT +V+  +  +PD + M  WV+      L  LL    +K   ++ +  E DD   T H   T + I D         RR  A V G                        N + +++  +EG+ +++ ++++++  ++ RDDW   A V+DR FL LF++  ++  +  F   P+
Sbjct:   68 DERRLLADVFG--SYDNKLRPVLSKTHNVTVKLGLTLNQIMDVIEKFELLSVSLYVRQKWENPLVAWNKSEYGGIVQVNLDPSTLWKPDIYLYNNADSGYDGSLYGFTAKIKVNYSGTNTWLAPKIFTTSCKINVKYFPFDQQECRLKFGSWTYDANSVDIF----PEEDQAS-------------IKGYQKNGEWDFIGFPCKRSILYYPCCPDSPFTDVTCTLIIRRKTLYYWVNLIIPCMLITVLSLLSFIVSTDSGERVGLVITDLLALTVFMLIVADILPPTSEVVPVISIYIICSTIEVGLALVATTIVVQCYHTNPDINVMPFWVKYFICQKLGGLLGITHVKDKKEEEQAKELDDETVTNHMGFTLNQIMDVEGIYDDDERRLLADVFGSYDNKLRPVLSKTHNVTVKLGLTLNQIMDVDHLVEGITKLIDNMEEQDEGNSKRDDWILAATVIDRFFLILFALVILLSTILTFATIPS 534          

Query:  189 LYDDLMRRRGYDPSVRPVKSYTST-VLLYMNLSLVQILDVDEKNQIIVLNMWVNQEWNDPNFVWDPNDYGNVTELNIPSREIWTPDLVLYNNAGGDWDLA-SSSNTKVIVNHDGSVLWKPPIIFKSQCGINVEFFPFDKQLCDLKIGTWTHNGFLIDLRHTAQKNQSQASFDNCNAKIDYAIDLSQYVNNVEWDLLEVSAKRNIEFYPCCTEPYLDISFNVSLRRRTLFYGINLICPCLAISFLTILVFYLPADSGEKXXXXXXXXXXXXXXXXXXXDISPPTSIVVPLILKYLLFTMILVTLSVMATVLVLNIHWRSPDTH--KMAPWVRSVFTSTLPKLLFMKKP-DQDYRDNETD-----------DIPETFHEDETDSNIQDKWSTRR----AAVSGDNVVNEIEL---------------------------------ALEGVRRIVHHIKKENSYSAMRDDWKYVAVVLDRLFLWLFSIAAIIGMLGIFMQAPTLT 1535
            L  DL++  GY+    PV     T  ++   L LVQ+++VD+KNQII  N+WV Q W +    WDP+ YG +T + I + +IW PD+VLYN+A  ++        T+VI+NHDG   W  P  F+S C I+V FFPFD+Q C +K G+WT    ++DL   A K+   +S               QY+ + EWDL+  S KRN+E+Y CCT P+ D++     RR+ LFY  NLI PCL I+ + +L F LP +SGE+++LSI++LL++ VF  L  +  P  S  VP++  + +  M+ V LS++AT  VL+IH ++       +  WV+      L K+L +KKP  +D  D  +            D+     + +    + +   + R     AVS D +++  +                                  A +G+  +  H+K +      + +W+Y+A+VLDRLF WLF +  I+    + +++P+++
Sbjct:   15 LLGDLLK--GYNKDAHPVPILNKTQYMVTFGLELVQLVNVDDKNQIITTNVWVRQRWTNLLLKWDPDKYGGITRVRIDASKIWIPDIVLYNSADSEFSGGLEKYKTRVILNHDGVNAWYSPASFRSTCQIDVTFFPFDQQTCFMKFGSWTFE--VVDLDIFADKSPLHSS---------------QYMKSAEWDLIAASKKRNVEYYACCTYPFSDVTVTWVFRRKPLFYVFNLIVPCLIITGMVLLGFMLPPESGERITLSITVLLAMAVFLQLAAENLPRNSDNVPVLGIFYITVMVEVALSLIATCYVLHIHHKNSGIAVVPVPHWVQVYMLGYLGKILGVKKPITEDTYDASSKLDFKRLSMMKRDMERAVGDGKRRFGLSNGGKSGRRLGSRAVSDDLLMDSFDQEDDTNSNSTNQNTTNNTGNNQRTFSVQSSMNTKATQGIIVLADHVKHKRLVEINQGEWRYLAMVLDRLFFWLFVLMIILSA-SVILRSPSIS 496          

Query:  168 GTKDARRLYDDLMRRRGYDPSVRPVKSYTSTVLLYMNLSLVQILDVDEKNQIIVLNMWVNQEWNDPNFVWDPNDYGNVTELNIPSREIWTPDLVLYNNAGGDWDLASSSNTKVIVNHDGSVLWKPPIIFKSQCGINVEFFPFDKQLCDLKIGTWTHNGFLIDLRHTAQKNQSQASFDNCNAKIDYAIDLSQYVNNVEWDLLEVSAKRNIEFYPCCTEPYLDISFNVSLRRRTLFYGINLICPCLAISFLTILVFYLPADSGEKXXXXXXXXXXXXXXXXXXXDISPPTSIVVPLILKYLLFTMILVTLSVMATVLVLNIHWRSPDTHKMAPWVRSVFTSTLPKLLFMKKP-DQD------------YRDNETDDIPETFHED------------ETDSNIQDKWSTRRAA----VSGDNVVNEIELALEGVRRIVHHIKKENSYSAMRDDWKYVAVVLDRLFLWLFSIAAIIGMLGIFMQ 1520
             +K   RL+  L RR  Y+  +RPV++ +  V +   +S+ Q++ VDE NQI+  N+W+   WND    W P ++  +  + +PS +IW PD+VLYNNA GD+ +     TK ++  DG++ W PP IFKS C +++ +FPFD Q C +K G+WT++   IDL     K                 ++L  +  + EW++++    ++   Y CC E Y DI+++  +RR  LFY INLI PCL ISFLT+LVFYLP+D GEKV+L IS+LLSLTVF L+I +  P TS+V+PLI +YLLFTMI VTLS++ TV VLN+H+R+P TH M  WV  VF   LP+++ M++P D+D            Y D +   +     +             ET ++++ K    + +    V+   V  E++ A+E V+ I  +++  N    + DDWKYVA+V+DR+FLW+F    ++G +G+F+Q
Sbjct:   25 SSKAEDRLFRKLFRR--YNQFIRPVENVSDPVTVEFEVSISQLVKVDEVNQIMETNLWLRHIWNDYKLRWTPAEFDGIEFIRVPSNKIWRPDIVLYNNAVGDFLV--EDKTKALLKFDGTITWVPPAIFKSSCPMDITYFPFDYQNCSMKFGSWTYDKAKIDLVLIGSK-----------------VNLKDFWESGEWEIIDAPGYKHDIKYNCCEEIYPDITYSFYIRRLPLFYTINLIIPCLLISFLTVLVFYLPSDCGEKVTLCISVLLSLTVFLLVITETIPSTSLVIPLIGEYLLFTMIFVTLSIVITVFVLNVHYRTPMTHTMPGWVHLVFLKVLPRIMLMRRPTDEDGKVGGGSLNCLEYGDCKLSSMDGCGAKKCPCPCQHGRETPETAASVRMKHQLSQQSINTVVAFSVVSPEVKQAIESVKYIAENMRSRNKAKEVEDDWKYVAMVIDRIFLWVFVTVCLLGTMGLFLQ 483          

Query:  156 FIVQGTKDARRLYDDLMRRRGYDPSVRPVKSYTSTVLLYMNLSLVQILDVDEKNQIIVLNMWVNQEWNDPNFVWDPNDYGNVTELNIPSREIWTPDLVLYNNAGGDWDLASSSNTKVIVNHDGSVLWKPPIIFKSQCGINVEFFPFDKQLCDLKIGTWTHNGFLIDLRHTAQKNQSQASFDNCNAKIDYAIDLSQYVNNVEWDLLEVSAKRNIEFYPCCTEPYLDISFNVSLRRRTLFYGINLICPCLAISFLTILVFYLPADSGEKXXXXXXXXXXXXXXXXXXXDISPPTSIVVPLILKYLLFTMILVTLSVMATVLVLNIHWRSPDTHKMAPWVRSVFTSTLPKLLFMKKPDQDYRDNETDDIPETFHEDETDSNIQDKWSTRRAAVSGDNVVNEIELALEGVRRIVHHIKKENSYSAMRDDWKYVAVVLDRLFLWLFSIAAIIGMLGIFMQ 1520
            F   G     RL + L+    Y+  +RP  + +  V + + +SL Q++ V E+ Q++  N+W+ QEW D    W P ++  + ++ +PS+ IW PD+VLYNNA G ++++  SN   +V++DGS+ W PP I+KS C I V+ FPFD+Q C L+  +WT++   IDL   A      AS D+             +  + EWD++ +  +RN          Y+DI+++  +RR+ LFY INLI PC+ I+ L ILVFYLP+D GEK++L IS+LL+LTVF LLI  I PPTS+ VPL+ KYL+FTM+LVT S++ +V VLN+H RSP TH M PWV+ VF + LP LLFM++P                 + E      D       ++ G N       A+EGVR I +H+K E+   ++ +DWKYVA+V+DRLFLW+F    + G LG+F+Q
Sbjct:   33 FCSLGADTEERLVEHLLNPAHYNKLIRPATNGSELVTVQLMVSLAQLISVHEREQVMTTNVWLTQEWQDYRLTWVPEEFDGMLKVRLPSKHIWLPDVVLYNNADGVYEVSFYSNA--VVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTLRFRSWTYDRTEIDLVLRAD----VASMDD-------------FTPSGEWDIIALPGRRNEN---PADPAYVDITYDFIIRRKPLFYTINLIIPCVLITSLAILVFYLPSDCGEKMTLCISVLLALTVFLLLISKIVPPTSLDVPLVGKYLMFTMVLVTFSIVTSVCVLNVHHRSPTTHTMPPWVKLVFLNKLPALLFMRQPRNSCERQRLRQRRRAQEQREVKQFGGDLGGAGGGSMDGLN-----REAVEGVRFIANHMKSEDDDQSVSEDWKYVAMVIDRLFLWIFVFVCVFGTLGMFLQ 460          

Query:  186 RLYDDLMRR--RGYDPSVRPVKSYTSTVLLYMNLSLVQILDVDEKNQIIVLNMWVNQEWNDPNFVWDPNDYGNVTELNIPSREIWTPDLVLYNNAGGDWDLASSSNTKVIVNHDGSVLWKPPIIFKSQCGINVEFFPFDKQLCDLKIGTWTHNGFLIDLRHTAQKNQSQASFDNCNAKIDYAIDLSQYVNNVEWDLLEVSAKRNIEFYPCCTEPYLDISFNVSLRRRTLFYGINLICPCLAISFLTILVFYLPADSGEKXXXXXXXXXXXXXXXXXXXDISPPTSIVVPLILKYLLFTMILVTLSVMATVLVLNIHWRSPDT-HKMAPWVRSVFTSTLPKLLFMKKPDQDYRDNETDDIPETFHEDETDSNIQDKWSTRRAAVSG-----DNVVNEIELALEGVRRIVHHIKKENSYSAMRDDWKYVAVVLDRLFLWLFSIAAIIGMLGIFMQA 1523
             L D L+R   +GY   VRPV+    T+ +   L + Q++DVDEKNQ++  N+W+ QEW D    W+P+DYG +T + +PS  IW PD+VLY NA G ++   S  TK IV  DG++ W PP  +KS C ++V FFPFD+Q C +K G+WT++G ++DL                   +D+ +D   + +N EW++L  + +R          P+L  SF   L+R  LFY + LI PCL +SFLT+LVFYLP+D GEK+SLS S+L+SLTVF L+I +I P +S V+PLI +YLLF MI VT S++ TV V+N+H RS  T H MAPWV+S+F   LP+LL M+     Y   + +                     ++ A+ G        +  +E A   V  I  HI+KE+    +  DWK+VA VLDR+FLW F   +I+G + IF  A
Sbjct:   32 ELEDSLLRNLFKGYQKWVRPVQHANDTITVRFGLKISQLVDVDEKNQLMTTNVWLWQEWIDVKLKWNPDDYGGITSIRVPSETIWLPDIVLYENADGRFE--GSLMTKAIVRWDGTITWTPPASYKSSCTMDVTFFPFDRQNCSMKFGSWTYDGNMVDL-----------------VLVDHYVDRKDFFDNGEWEILNATGQRGSRRDEMYWYPFLTYSF--ILKRLPLFYTLFLIIPCLGLSFLTVLVFYLPSDEGEKLSLSTSVLVSLTVFLLVIEEIIPSSSKVIPLIGEYLLFIMIFVTFSIIVTVFVINVHHRSSATYHPMAPWVKSLFLQKLPRLLCMRGHTDRYHFPDIEMRSPELKTRRGAGRRAVPGGQQKGALGGMEDDSQAWLAMLEKATNSVHYISRHIRKEHFIREVVQDWKFVAQVLDRIFLWAFLTVSILGTVLIFTPA 464          

Query:  195 DDLMRR--RGYDPSVRPVKSYTSTVLLYMNLSLVQILDVDEKNQIIVLNMWVNQEWNDPNFVWDPNDYGNVTELNIPSREIWTPDLVLYNNAGGDWDLASSSNTKVIVNHDGSVLWKPPIIFKSQCGINVEFFPFDKQLCDLKIGTWTHNGFLIDLRHTAQKNQSQASFDNCNAKIDYAIDLSQYVNNVEWDLLEVSA-----KRNIEFYPCCTEPYLDISFNVSLRRRTLFYGINLICPCLAISFLTILVFYLPADSGEKXXXXXXXXXXXXXXXXXXXDISPPTSIVVPLILKYLLFTMILVTLSVMATVLVLNIHWRSPDT-HKMAPWVRSVFTSTLPKLLFMKKPDQDYRDNE-TDDIPETFHEDETDSNIQDKWSTRRAAVSGDNVVNE-----IELALEGVRRIVHHIKKENSYSAMRDDWKYVAVVLDRLFLWLFSIAAIIGMLGIFMQA 1523
            DDL++   +GY   VRP++    TV +   L + Q++DVDEKNQ++  N+W+ QEW D    W+P+ YG +T + +PS  IW PD+VLY NA G ++   S  TK IV  +G+V W PP  +KS C ++V FFPFD+Q C +K G+WT++G ++DL                   +D  +D   + +N EW++L  +      K  + FYP  T  ++       L+R  LFY + LI PCL +SFLT+LVFYLP+D GEK+SLS S+L+SLTVF L+I +I P +S V+PLI +YLLF MI VTLS++ TV V+N+H RS  T H M+PWVRS+F   LP+LL M+     Y   E   + P           IQ + S+     + D    E     +E A+  VR I  HI+K++    +  DWK+VA VLDR+FLW+F   +++G + IF  A
Sbjct:   35 DDLLKNLFQGYQRWVRPIQRPNDTVRVRFGLKISQLVDVDEKNQLMTTNVWLRQEWIDYKLRWNPDKYGGITSIRVPSENIWLPDIVLYENADGKFE--GSLMTKAIVKFNGAVTWMPPASYKSACTMDVTFFPFDRQNCSMKFGSWTYDGNMVDL-----------------VLMDSQVDRKDFFDNGEWEILSATGAKGNRKDGLYFYPFITCSFI-------LKRLPLFYTLFLIIPCLGLSFLTVLVFYLPSDEGEKLSLSTSVLVSLTVFLLVIEEIIPSSSKVIPLIGEYLLFIMIFVTLSIIVTVFVINVHHRSSATYHPMSPWVRSLFLQKLPRLLCMRGHADRYHYPELAPESPALKSRSGGRRGIQ-RMSSGGQQSTYDGKEEEAYSTMLEKAIYSVRYISRHIRKDHFIREVVQDWKFVAQVLDRIFLWIFLSVSVLGTILIFTPA 464          

Query:  177 DARRLYDDLMRRRGYDPSVRPVKSYTSTVLLYMNLSLVQILDVDEKNQIIVLNMWVNQEWNDPNFVWDPNDYGNVTELNIPSREIWTPDLVLYNNAGGDWDLASSSNTKVIVNHDGSVLWKPPIIFKSQCGINVEFFPFDKQLCDLKIGTWTHNGFLIDLRHTAQKNQSQASFDNCNAKIDYAIDLSQYVNNVEWDLLEVSAKRNIEFYPCCTEPYLDISFNVSLRRRTLFYGINLICPCLAISFLTILVFYLPADSGEKXXXXXXXXXXXXXXXXXXXDISPPTSIVVPLILKYLLFTMILVTLSVMATVLVLNIHWRSPDTHKMAPWVRSVFTSTLPKLLFMKKPDQDYRDNETDDIPETFHEDETDSNIQDKWSTRRA---------------------AVSGDNVV--------------------------NEIELA--LEGVRRIVHHIKKENSYSAMRDDWKYVAVVLDRLFLWLFSIAAIIGMLGIFMQAPTLTD 1538
            + RRLY DLM    Y+P  RPV + + ++ ++  LSL+QI+DVDEKNQ++  N+W+   WND    W+ +DY  VT +  P   IW PD++LYN+A   +D  ++ +T ++VN  G+  + PP IFKS C I+V +FPFD Q C+LK G+WT+ G+ +DL+                       D+S Y+ N EWDL+EV  +RN  FY CC EPYLDI+F V +RRRTL+YG+NL+ PC+ IS L +LVF LPADSGEK+SL I++LLSLTVF LL+ +I P TS  VPLI +Y   TM++V LSV+ATVLVL  H   PD  KM  W R +  +     L MK+P +D   +  D+  +T     T  ++    ST  +                     A S D+ V                           E+ELA  L+ VR I    + ++   ++ ++WK+ A V+DRL L  FS+  I+  +GI M AP   +
Sbjct:   49 NQRRLYSDLMST--YNPLERPVYNDSQSLTVHFGLSLLQIMDVDEKNQVLTTNIWLRLYWNDHYLQWNSSDYPGVTNVRFPDHLIWKPDILLYNSADERFD--ATFHTNILVNSSGTCSYLPPGIFKSTCYIDVRWFPFDVQRCELKFGSWTYGGWSLDLKMLEA-------------------DVSGYIANGEWDLVEVPGQRNERFYECCDEPYLDITFTVVMRRRTLYYGLNLLLPCVLISTLALLVFLLPADSGEKISLGITVLLSLTVFMLLVAEIMPATSDSVPLIAEYFATTMVIVGLSVIATVLVLQYHHHDPDGGKMPKWTRVILLNWCAWFLRMKRPGEDRVRSACDN--KTRRSSLTSMDLNAPTSTSLSTNGNLLYVGVRGLESLQYSPGATSPDSGVVCGRLITRAGEDEMLLPSSHASSLGNMEMELAKILDEVRYIAKRFRDQDEDESVCNEWKFAASVVDRLCLMAFSLFTILCTIGILMSAPNFVE 526          

Query:  123 MICLGFLFGLIFIVQGTKDARRLYDDLMRRRGYDPSVRPVKSYTSTVLLYMNLSLVQILDVDEKNQIIVLNMWVNQEWNDPNFVWDPNDYGNVTELNIPSREIWTPDLVLYNNAGGDWDLASSSNTKVIVNHDGSVLWKPPIIFKSQCGINVEFFPFDKQLCDLKIGTWTHNGFLIDLRHTAQKNQSQASFDNCNAKIDYAIDLSQYVNNVEWDLLEVSAKRNIEFYPCCTEPYLDISFNVSLRRRTLFYGINLICPCLAISFLTILVFYLPADSGEKXXXXXXXXXXXXXXXXXXXDISPPTSIVVPLILKYLLFTMILVTLSVMATVLVLNIHWRSPDTHKMAPWVRSVFTSTLPKLLFMKKPDQDYRDNETDDIPETFHEDETDSNIQDKWSTRRAAVSGDNVVNEIELALEGVRRIVHHIKKENSYSAMRDDWKYVAVVLDRLFLWLFSIAAIIGMLG 1508
            MICLGFLFGLIFIVQGTKDARRLYDDLMRRRGYDPSVRPVKSYTSTVLLYMNLSLVQILDVDEKNQIIVLNMWVNQEWNDPNFVWDPNDYGNVTELNIPSREIWTPDLVLYNNAGGDWDLASSSNTKVIVNHDGSVLWKPPIIFKSQCGINVEFFPFDKQLCDLKIGTWTHNGFLIDLRHTAQKNQSQASFDNCNAKIDYAIDLSQYVNNVEWDLLEVSAKRNIEFYPCCTEPYLDISFNVSLRRRTLFYGINLICPCLAISFLTILVFYLPADSGEKVSLSISILLSLTVFFLLIFDISPPTSIVVPLILKYLLFTMILVTLSVMATVLVLNIHWRSPDTHKMAPWVRSVFTSTLPKLLFMKKPDQDYRDNETDDIPETFHEDETDSNIQDKWSTRRAAVSGDNVVNEIELALEGVRRIVHHIKKENSYSAMRDDWKYVAVVLDRLFLWLFSIAAIIGMLG
Sbjct:    1 MICLGFLFGLIFIVQGTKDARRLYDDLMRRRGYDPSVRPVKSYTSTVLLYMNLSLVQILDVDEKNQIIVLNMWVNQEWNDPNFVWDPNDYGNVTELNIPSREIWTPDLVLYNNAGGDWDLASSSNTKVIVNHDGSVLWKPPIIFKSQCGINVEFFPFDKQLCDLKIGTWTHNGFLIDLRHTAQKNQSQASFDNCNAKIDYAIDLSQYVNNVEWDLLEVSAKRNIEFYPCCTEPYLDISFNVSLRRRTLFYGINLICPCLAISFLTILVFYLPADSGEKVSLSISILLSLTVFFLLIFDISPPTSIVVPLILKYLLFTMILVTLSVMATVLVLNIHWRSPDTHKMAPWVRSVFTSTLPKLLFMKKPDQDYRDNETDDIPETFHEDETDSNIQDKWSTRRAAVSGDNVVNEIELALEGVRRIVHHIKKENSYSAMRDDWKYVAVVLDRLFLWLFSIAAIIGMLG 462          

Query:  132 LGFLFGLIFIVQGTKDARRLYDDLMRRRGYDPSVRPVKSYTSTVLLYMNLSLVQILDVDEKNQIIVLNMWVNQEWNDPNFVWDPNDYGNVTELNIPSREIWTPDLVLYNNAGGDWDLASSSNTKVIVNHDGSVLWKPPIIFKSQCGINVEFFPFDKQLCDLKIGTWTHNGFLIDLRHTAQK----NQSQASFDNCNAKIDYAIDLSQYVNNVEWDLLEVSAKRNIEFYPCCTEPYLDISFNVSLRRRTLFYGINLICPCLAISFLTILVFYLPADSGEKXXXXXXXXXXXXXXXXXXXDISPPTSIVVPLILKYLLFTMILVTLSVMATVLVLNIHWRSPDTHKMAPWVRSVFTSTLPKLLFMKKPDQDYRDNETDDIPETFHEDET----DSNIQD----KWS-------TRRAAVSGDNVVNEIELALEGVRRIVHHIKKENSYSAMRDDWKYVAVVLDRLFLWLFSIAAIIGMLGIFMQAPTLTDNAIPM-TADNCPSVSSINVTKL 1601
            L F+   I +      AR LYDDL  +    P + PV +  + V++YMNLSL QIL+V+ K+QIIVLN+WV QEWND  F WDP+DYG +TE+ IPS  IW PDLVLYNNAGGDWDL+  S +KV V HDG+++WKPP+I KSQC ++V +FPFD Q C LK+GTWTH+G LIDLRH AQK    +  +  +DNC +KIDYAIDL+ Y+ + EWDLL V+A RNI+ YPCC EPYLD++F++ +RR TLFYG+NLI PCL+ISFLTI+VFYLP  S +K++L IS+ L+L +F L++FD++P TS  VPLI+KYLLFTM +VT S++A++ VLN  +R P+T K++  ++ +F  TLP  L M+    ++++N   +IP +F   ++    D ++ D    KW+         ++  + +    +  LALE +R I +++  +   + +R++W Y+ +V+DRLFL +F++   +G L IF+  P L    + + + D    +++ N T+L
Sbjct:   10 LSFVAIKICVTTAYSAARNLYDDLFNKAHNYPKLLPVVNLETPVIVYMNLSLSQILEVNVKDQIIVLNVWVYQEWNDNRFSWDPSDYGGLTEIQIPSSMIWLPDLVLYNNAGGDWDLSGMSGSKVKVKHDGTIIWKPPVILKSQCEMDVTYFPFDIQTCPLKMGTWTHHGLLIDLRHWAQKVSDLSNERIKYDNCESKIDYAIDLTDYLQSYEWDLLSVTANRNIKKYPCCPEPYLDVTFHIKIRRMTLFYGLNLIFPCLSISFLTIMVFYLPTYSTQKITLCISVFLALNIFILVVFDLTPSTSRSVPLIVKYLLFTMFMVTFSIVASIAVLNFSFRQPETDKLSDNMKKIFLKTLPTYLKMR--SVEFKENS--EIPTSFGSTKSTNYADYSMYDLTWLKWNKGYTEMMNSKSGTAQNFSSAKRNLALESLRSIKYNLLLKTRRNEVRNEWMYMGIVIDRLFLIVFTVIVTLGSLIIFLMPPQLWSQQLVLNSKDAAQMLANSNYTRL 515          

Query:  132 LGFLFGLIFIVQGTKDARRLYDDLMRRRGYDPSVRPVKSYTSTVLLYMNLSLVQILDVDEKNQIIVLNMWVNQEWNDPNFVWDPNDYGNVTELNIPSREIWTPDLVLYNNAGGDWDLASSSNTKVIVNHDGSVLWKPPIIFKSQCGINVEFFPFDKQLCDLKIGTWTHNGFLIDLRHTAQKNQSQASFDNCNAKIDYAIDLSQYVNNVEWDLLEVSAKRNIEFYPCCTEPYLDISFNVSLRRRTLFYGINLICPCLAISFLTILVFYLPADSGEKXXXXXXXXXXXXXXXXXXXDISPPTSIVVPLILKYLLFTMILVTLSVMATVLVLNIHWRSPDTHKMAPWVRSVFTSTLPKLLFMKKPDQDYRDN--------ETDDIPETFHEDETDSNIQDKWSTRRAAVSGDNVV--------------------------------------NE----IELALEGVRRIVHHIKKENSYSAMRDDWKYVAVVLDRLFLWLFSIAAIIGMLGIFMQAPTLTDNAIPMTADNCPSVSSI 1586
            +   + LI I    KDA RLY  LM    Y   +RPV      + +Y+ L L Q+ +V+ + + +  N+W+ Q+W D N  W+PN YG VT+L IPS +IW PD+VL+NN  G +++  S  TK  V HDG+V W PP I+KS C INVEFFP+D Q C L   +WT+ G  ++L+H AQKN            ID+A+DL+ +  +VE+D+LE+SA+R++  Y    +P   ++F + +RR+TLFY +NL+ PCLAI FL++L FYLP++SGEKV LSI+IL SLT+FFLL+ +  P TS+V+PLI KYLLFTMIL++LS++ TV +LN+H+RS  +H M  WV+ +F  TLP+LL + +P +  R           T  +    ++  T +N    +  R       N                                        NE    I+ A++ V+ + + ++ ++  + +++DWK+VA+V+DRLFLW FS A ++  LGI +Q+P L D   P+ ++N P+ +++
Sbjct:    8 IAVFYVLIPINHAYKDAIRLYKVLMDGSNYSNYIRPVNYNNDVLTVYLGLRLSQLSEVNMRKETVTTNVWLEQQWIDVNLRWNPNQYGGVTKLYIPSDKIWLPDIVLFNNIDGKYEI--SIKTKATVFHDGTVKWIPPAIYKSSCQINVEFFPYDIQECFLTFASWTYEGSKVNLKHMAQKNVIDIPNATGMVNIDFAVDLTNFYESVEFDILELSAERSLVTY---LQPSPKVTFKILMRRKTLFYTVNLMMPCLAICFLSVLAFYLPSESGEKVYLSITILFSLTLFFLLLVETIPSTSLVIPLIGKYLLFTMILISLSIILTVYILNVHFRSSLSHDMPDWVKQIFLITLPRLLLIDRPKKTIRPKPCKHNSKCSTKFVATENNQPCTSNNTSYSYQYRYMPADASNYTFTSHLTQDSTAQWSVEPKRKVYRSSKQSSKSQLKPDSENELDWKIDRAIDEVQFVANQLRADDESNDIKEDWKFVAMVMDRLFLWTFSSACLMSTLGIILQSPALYDTRKPIHSNNVPNCTNL 537          

Query:  132 LGFLFGLIFIVQGTKDARRLYDDLMRRRGYDPSVRPVKSYTSTVLLYMNLSLVQILDVDEKNQIIVLNMWVNQEWNDPNFVWDPNDYGNVTELNIPSREIWTPDLVLYNNAGGDWDLASSSNTKVIVNHDGSVLWKPPIIFKSQCGINVEFFPFDKQLCDLKIGTWTHNGFLIDLRHTAQKNQSQASFDNCNAKIDYAIDLSQYVNNVEWDLLEVSAKRNIEFYPCCTEPYLDISFNVSLRRRTLFYGINLICPCLAISFLTILVFYLPADSGEKXXXXXXXXXXXXXXXXXXXDISPPTSIVVPLILKYLLFTMILVTLSVMATVLVLNIHWRSPDTHKMAPWVRSVFTSTLPKLLFMKKPDQDYRDN--------ETDDIPETFHEDETDSNIQDKWSTRRAAVSGDNVV--------------------------------------NE----IELALEGVRRIVHHIKKENSYSAMRDDWKYVAVVLDRLFLWLFSIAAIIGMLGIFMQAPTLTDNAIPMTADNCPSVSSI 1586
            +   + LI I    KDA RLY  LM    Y   +RPV      + +Y+ L L Q+ +V+ + + +  N+W+ Q+W D N  W+PN YG VT+L IPS +IW PD+VL+NN  G +++  S  TK  V HDG+V W PP I+KS C INVEFFP+D Q C L   +WT+ G  ++L+H AQKN            ID+A+DL+ +  +VE+D+LE+SA+R++  Y    +P   ++F + +RR+TLFY +NL+ PCLAI FL++L FYLP++SGEKV LSI+IL SLT+FFLL+ +  P TS+V+PLI KYLLFTMIL++LS++ TV +LN+H+RS  +H M  WV+ +F  TLP+LL + +P +  R           T  +    ++  T +N    +  R       N                                        NE    I+ A++ V+ + + ++ ++  + +++DWK+VA+V+DRLFLW FS A ++  LGI +Q+P L D   P+ ++N P+ +++
Sbjct:   56 IAVFYVLIPINHAYKDAIRLYKVLMDGSNYSNYIRPVNYNNDVLTVYLGLRLSQLSEVNMRKETVTTNVWLEQQWIDVNLRWNPNQYGGVTKLYIPSDKIWLPDIVLFNNIDGKYEI--SIKTKATVFHDGTVKWIPPAIYKSSCQINVEFFPYDIQECFLTFASWTYEGSKVNLKHMAQKNVIDIPNATGMVNIDFAVDLTNFYESVEFDILELSAERSLVTY---LQPSPKVTFKILMRRKTLFYTVNLMMPCLAICFLSVLAFYLPSESGEKVYLSITILFSLTLFFLLLVETIPSTSLVIPLIGKYLLFTMILISLSIILTVYILNVHFRSSLSHDMPDWVKQIFLITLPRLLLIDRPKKTIRPKPCKHNSKCSTKFVATENNQPCTSNNTSYSYQYRYMPADASNYTFTSHLTQDSTAQWSVEPKRKVYRSSKQSSKSQLKPDSENELDWKIDRAIDEVQFVANQLRADDESNDIKEDWKFVAMVMDRLFLWTFSSACLMSTLGIILQSPALYDTRKPIHSNNVPNCTNL 585          

Query:  168 GTKDARRLYDDLMRRRGYDPSVRPVKSYTSTVLLYMNLSLVQILDVDEKNQIIVLNMWVNQEWNDPNFVWDPNDYGNVTELNIPSREIWTPDLVLYNNAGGDWDLASSSNTKVIVNHDGSVLWKPPIIFKSQCGINVEFFPFDKQLCDLKIGTWTHNGFLIDLRHTAQKNQSQASFDNCNAKIDYAIDLSQYVNNVEWDLLEVSAKRNIEFYPCCTEPYLDISFNVSLRRRTLFYGINLICPCLAISFLTILVFYLPADSGEKXXXXXXXXXXXXXXXXXXXDISPPTSIVVPLILKYLLFTMILVTLSVMATVLVLNIHWRSPDTHKMAPWVRSVFTSTLPKLLFMKKPDQDYRD---------NETDDIPETFHEDETDSNIQDKW---STRRAAVSGDNVVNEIELALEGVRRIVHHIKKENSYSAMRDDWKYVAVVLDRLFLWLFSIAAIIGMLGIFMQAPTLTDNAIPMTADNCPSVSSINVTKLTCET 1613
            G K A +LY  L+    Y+  +RPV+     V  Y  L L Q++D++ ++Q +  N+WV QEW D N  W+P DY  V  L+IPS +IW PD+VLYN A G +++   +  KV   HDG+V W PP +++S C INVEFFP+D Q C +   +WT+N   + L+H  QK    +S  +    I++A+DL  +  +VE+D+LE+SA+R+I  +   +E + +++FN+ +RR+TLFY +NLI PCLA+SFL++LVFYLP  SGEK               + + +  P TS+V+PLI KYLLFT+IL++LS++ TV+VLN+++RS  TH M+PW+R +F   LP +LF+  P    ++         N+T      F E      I + +   S R  ++   ++  +I   +  ++ +V ++K ++  + ++++W++VAVV+DR+FL LF  A +I    I +++P L D   P+  ++ P     N T LT  T
Sbjct:   24 GFKSAVQLYQKLLDENNYNKLIRPVERNEDAVTTYFGLKLTQLIDLNMRDQKLTTNVWVQQEWQDVNLRWNPEDYEGVQLLHIPSNKIWLPDIVLYNTADGKYEVKLMTKAKVF--HDGTVKWTPPAVYRSSCHINVEFFPYDIQNCQMTFASWTYNDHKMVLKHYTQKGIPDSSNTSGTVVINHAVDLRNFYTSVEFDILELSARRHIRQFQGESEKFPEVTFNIIMRRKTLFYTVNLIMPCLAVSFLSVLVFYLPTQSGEK---------------ISLIETIPSTSLVIPLIGKYLLFTIILISLSIIITVIVLNVNFRSTMTHSMSPWIRYIFLKFLPPILFLHSPISKEKEMSERCFMYCNKT-----MFKEASVSKLIYETFMRRSKRSYSLKDASIEEKINRTIADLKYVVDNLKDDDYKNKVQEEWRFVAVVMDRVFLLLFLSACVISTGSIILRSPALYDRRTPLDGNHLP-----NQTLLTYST 490