ERO1-like protein beta

Overview
NameERO1-like protein beta
Smed IDSMED30008709
Length (bp)1954
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of ERO1-like protein beta (SMED30008709) t-SNE clustered cells

Violin plots show distribution of expression levels for ERO1-like protein beta (SMED30008709) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of ERO1-like protein beta (SMED30008709) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for ERO1-like protein beta (SMED30008709) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30008709

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 8

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
intestinal phagocyteSMED30008709h1SMcG0007500 Contig637newmark_estsPMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
intestinal phagocyteSMED30008709h1SMcG0007500 Contig637uc_Smed_v2PMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
intestinal phagocyteSMED30008709h1SMcG0021436 Contig637newmark_estsPMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
intestinal phagocyteSMED30008709h1SMcG0021436 Contig637uc_Smed_v2PMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
gutSMED30008709h1SMcG0021436 dd_Smed_v4_6558_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parapharyngeal regionSMED30008709h1SMcG0021436 dd_Smed_v4_6558_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymaSMED30008709h1SMcG0021436 dd_Smed_v4_6558_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30008709h1SMcG0021436 dd_Smed_v4_6558_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of ERO1-like protein beta vs. Ensembl Human
Match: ERO1B (endoplasmic reticulum oxidoreductase 1 beta [Source:HGNC Symbol;Acc:HGNC:14355])

HSP 1 Score: 397.127 bits (1019), Expect = 9.672e-132
Identity = 207/447 (46.31%), Postives = 281/447 (62.86%), Query Frame = 1 
Query:  175 VDDCSCPVTDLEDYNT-KIYPILQSLLVKDYFRYFKINLNRECPFWVDDSRCALRDCHVKGCGPKEIPKGLQEDDPVYIEHQKSKYFGTPNIVHHPE-CLDENHGGLGNLDISISQTQKEVMHNWTIYDDQQDNFCEIDDENANGATYVDLTKNPERFTGYMGKSAHRIWNSIYKENCFNEHR-----NKYGINLHDAEYLGFLNVIDREQCLEKRIFYRIISGLHTSISIHLCREYLLKDKTGFGSPQWGPNVTEFAKRFDPKFEK-DGPQRLKNLFFTYLVELRAIAKVADYLSED--QFYTGDEVDDKETRLAVKHFLTQVKNFTNHFDEQKLFKGDPKEAKKLKHEFVQHFRNITRIINCVGCDKCKLWGTLQVKGMGTALKILFTNPAT---PEKTSADKDSFTKISSKFQLTRTEIVALFNAFGRLSTSVHSLSLFKDLMK 1476
            +DDC C +  ++++NT KI+P ++ L  +DYFRY+K+NL R CPFW +D  C+++DCHV+ C   +IP G++           +KY    N     E C  E    LG ++ ++S   KE   +W  YDD +D+FCE+DDE +  A YVDL  NPER+TGY G SA R+WNSIY+ENCF         N    +  + +   F   ++   CLEKR+FY++ISGLH SI++HLC  YLL++   +G P WGPN+ EF  RFDP   K +GP+RLKNL+F YL+ELRA++KVA Y        YTG+  +D +T+  + +     K+F  HFDE+ +F GD K AK LK EF  HF+NI+RI++CVGCDKC+LWG LQ +G+GTALKILF+       PE +          S  FQLTR EIVAL NAFGRLSTS+  L  FK L++
Sbjct:   39 LDDCLCDIDSIDNFNTYKIFPKIKKLQERDYFRYYKVNLKRPCPFWAEDGHCSIKDCHVEPCPESKIPVGIKAG-------HSNKYLKMANNTKELEDC--EQANKLGAINSTLSNQSKEAFIDWARYDDSRDHFCELDDERSPAAQYVDLLLNPERYTGYKGTSAWRVWNSIYEENCFKPRSVYRPLNPLAPSRGEDDGESFYTWLE-GLCLEKRVFYKLISGLHASINLHLCANYLLEET--WGKPSWGPNIKEFKHRFDPVETKGEGPRRLKNLYFLYLIELRALSKVAPYFERSIVDLYTGNAEEDADTKTLLLNIFQDTKSFPMHFDEKSMFAGDKKGAKSLKEEFRLHFKNISRIMDCVGCDKCRLWGKLQTQGLGTALKILFSEKEIQKLPENSP---------SKGFQLTRQEIVALLNAFGRLSTSIRDLQNFKVLLQ 464
[Close]
BLAST of ERO1-like protein beta vs. Ensembl Human
Match: ERO1A (endoplasmic reticulum oxidoreductase 1 alpha [Source:HGNC Symbol;Acc:HGNC:13280])

HSP 1 Score: 388.652 bits (997), Expect = 1.962e-128
Identity = 209/456 (45.83%), Postives = 290/456 (63.60%), Query Frame = 1 
Query:  139 AVDRCFCKLNESVDDCSCPVTDLEDYNT-KIYPILQSLLVKDYFRYFKINLNRECPFWVDDSRCALRDCHVKGCGPKEIPKGLQEDDPVYIEHQKSKYFGTPNIVHHPECLDENHGGLGNLDISISQTQKEVMHNWTIYDDQQDNFCEIDDENANGATYVDLTKNPERFTGYMGKSAHRIWNSIYKENCFNEHRNKYGIN-----LHDAEYLGFLNVIDREQCLEKRIFYRIISGLHTSISIHLCREYLLKDKTGFGSPQWGPNVTEFAKRFDPKF-EKDGPQRLKNLFFTYLVELRAIAKVADYLSED--QFYTGDEVDDKETRLAVKHFLTQVKNFTNHFDEQKLFKGDPKEAKKLKHEFVQHFRNITRIINCVGCDKCKLWGTLQVKGMGTALKILFTNPATPEKTSADKDSFTKISSKFQLTRTEIVALFNAFGRLSTSVHSLSLFKDLMKD 1479
            A  RCFC+++  +DDC+C V  ++ +N  +++P LQ LL  DYFRY+K+NL R CPFW D S+C  RDC VK C   E+P G++     Y E          N++   EC  E    LG +D S+S+  ++ +  WT +DD  DNFCE DD  +  A YVDL  NPER+TGY G  A +IWN IY+ENCF     K  +N        +E   F + ++   C+EKR FYR+ISGLH SI++HL   YLL++   +   +WG N+TEF +RFD    E +GP+RLKNL+F YL+ELRA++KV  +      Q +TG+++ D+E ++ +   L ++K+F  HFDE   F GD KEA KLK +F  HFRNI+RI++CVGC KC+LWG LQ +G+GTALKILF+     EK  A+    +  S +F LTR EIV+LFNAFGR+STSV  L  F++L+++
Sbjct:   31 AAQRCFCQVSGYLDDCTCDVETIDRFNNYRLFPRLQKLLESDYFRYYKVNLKRPCPFWNDISQCGRRDCAVKPCQSDEVPDGIKSASYKYSEEAN-------NLIE--EC--EQAERLGAVDESLSEETQKAVLQWTKHDDSSDNFCEADDIQSPEAEYVDLLLNPERYTGYKGPDAWKIWNVIYEENCFKPQTIKRPLNPLASGQGTSEENTFYSWLEG-LCVEKRAFYRLISGLHASINVHLSARYLLQET--WLEKKWGHNITEFQQRFDGILTEGEGPRRLKNLYFLYLIELRALSKVLPFFERPDFQLFTGNKIQDEENKMLLLEILHEIKSFPLHFDENSFFAGDKKEAHKLKEDFRLHFRNISRIMDCVGCFKCRLWGKLQTQGLGTALKILFS-----EKLIANMPE-SGPSYEFHLTRQEIVSLFNAFGRISTSVKELENFRNLLQN 466
[Close]
BLAST of ERO1-like protein beta vs. Ensembl Human
Match: ERO1B (endoplasmic reticulum oxidoreductase 1 beta [Source:HGNC Symbol;Acc:HGNC:14355])

HSP 1 Score: 184.496 bits (467), Expect = 3.046e-54
Identity = 95/182 (52.20%), Postives = 120/182 (65.93%), Query Frame = 1 
Query:  901 WGPNVTEFAKRFDPKFEK-DGPQRLKNLFFTYLVELRAIAKVADYLSED--QFYTGDEVDDKETRLAVKHFLTQVKNFTNHFDEQKLFKGDPKEAKKLKHEFVQHFRNITRIINCVGCDKCKLWGTLQVKGMGTALKILFTNPAT---PEKTSADKDSFTKISSKFQLTRTEIVALFNAFGR 1428
            WGPN+ EF  RFDP   K +GP+RLKNL+F YL+ELRA++KVA Y        YTG+  +D +T+  + +     K+F  HFDE+ +F GD K AK LK EF  HF+NI+RI++CVGCDKC+LWG LQ +G+GTALKILF+       PE +          S  FQLTR EIVAL NAFGR
Sbjct:    1 WGPNIKEFKHRFDPVETKGEGPRRLKNLYFLYLIELRALSKVAPYFERSIVDLYTGNAEEDADTKTLLLNIFQDTKSFPMHFDEKSMFAGDKKGAKSLKEEFRLHFKNISRIMDCVGCDKCRLWGKLQTQGLGTALKILFSEKEIQKLPENSP---------SKGFQLTRQEIVALLNAFGR 173
[Close]
BLAST of ERO1-like protein beta vs. Ensembl Human
Match: ERO1A (endoplasmic reticulum oxidoreductase 1 alpha [Source:HGNC Symbol;Acc:HGNC:13280])

HSP 1 Score: 170.629 bits (431), Expect = 6.032e-48
Identity = 88/201 (43.78%), Postives = 119/201 (59.20%), Query Frame = 1 
Query:  136 NAVDRCFCKLNESVDDCSCPVTDLEDYNT-KIYPILQSLLVKDYFRYFKINLNRECPFWVDDSRCALRDCHVKGCGPKEIPKGLQEDDPVYIEHQKSKYFGTPNIVHHPECLDENHGGLGNLDISISQTQKEVMHNWTIYDDQQDNFCEIDDENANGATYVDLTKNPERFTGYMGKSAHRIWNSIYKENCFNEHRNKYGIN 735
             A  RCFC+++  +DDC+C V  ++ +N  +++P LQ LL  DYFRY+K+NL R CPFW D S+C  RDC VK C   E+P G++     Y E          N++   EC  E    LG +D S+S+  ++ +  WT +DD  DNFCE DD  +  A YVDL  NPER+TGY G  A +IWN IY+ENCF     K  +N
Sbjct:   30 TAAQRCFCQVSGYLDDCTCDVETIDRFNNYRLFPRLQKLLESDYFRYYKVNLKRPCPFWNDISQCGRRDCAVKPCQSDEVPDGIKSASYKYSEEAN-------NLIE--EC--EQAERLGAVDESLSEETQKAVLQWTKHDDSSDNFCEADDIQSPEAEYVDLLLNPERYTGYKGPDAWKIWNVIYEENCFKPQTIKRPLN 219
[Close]
BLAST of ERO1-like protein beta vs. Ensembl Human
Match: ERO1A (endoplasmic reticulum oxidoreductase 1 alpha [Source:HGNC Symbol;Acc:HGNC:13280])

HSP 1 Score: 170.629 bits (431), Expect = 6.032e-48
Identity = 88/201 (43.78%), Postives = 119/201 (59.20%), Query Frame = 1 
Query:  136 NAVDRCFCKLNESVDDCSCPVTDLEDYNT-KIYPILQSLLVKDYFRYFKINLNRECPFWVDDSRCALRDCHVKGCGPKEIPKGLQEDDPVYIEHQKSKYFGTPNIVHHPECLDENHGGLGNLDISISQTQKEVMHNWTIYDDQQDNFCEIDDENANGATYVDLTKNPERFTGYMGKSAHRIWNSIYKENCFNEHRNKYGIN 735
             A  RCFC+++  +DDC+C V  ++ +N  +++P LQ LL  DYFRY+K+NL R CPFW D S+C  RDC VK C   E+P G++     Y E          N++   EC  E    LG +D S+S+  ++ +  WT +DD  DNFCE DD  +  A YVDL  NPER+TGY G  A +IWN IY+ENCF     K  +N
Sbjct:   30 TAAQRCFCQVSGYLDDCTCDVETIDRFNNYRLFPRLQKLLESDYFRYYKVNLKRPCPFWNDISQCGRRDCAVKPCQSDEVPDGIKSASYKYSEEAN-------NLIE--EC--EQAERLGAVDESLSEETQKAVLQWTKHDDSSDNFCEADDIQSPEAEYVDLLLNPERYTGYKGPDAWKIWNVIYEENCFKPQTIKRPLN 219
[Close]
BLAST of ERO1-like protein beta vs. Ensembl Celegans
Match: ero-1 (Endoplasmic reticulum oxidoreductin-1 [Source:UniProtKB/Swiss-Prot;Acc:Q7YTU4])

HSP 1 Score: 345.125 bits (884), Expect = 6.791e-112
Identity = 190/450 (42.22%), Postives = 271/450 (60.22%), Query Frame = 1 
Query:  151 CFCKLNESVDDCSC--PVTDLEDYNTKIYPILQSLLVKDYFRYFKINLNRECPFWVDDSRCALRDCHVKGCGPKEIPKGLQEDDPVYIEHQKSKYFGTPNIVHHPECLDENHGGLGNLDISISQTQKEVMHNWTIYDDQ-QDNFCEIDDENANGATYVDLTKNPERFTGYMGKSAHRIWNSIYKENCFNEHRNKYGINLHDAEYLGFLNVIDREQCLEKRIFYRIISGLHTSISIHLCREYLLKDKTG----FGSPQ--WGPNVTEFAKRFDPKFEKDGPQRLKNLFFTYLVELRAIAKVADYLSEDQFYTGDEVDDKETRLAVKHFLTQVKNFTNHFDEQKLFKGDPKEAKKLKHEFVQHFRNITRIINCVGCDKCKLWGTLQVKGMGTALKILFTNPATPEKTSADKDSFTKISSKFQLTRTEIVALFNAFGRLSTSVHSLSLFKDLM 1473
            CFCK  E+V+ C C  P T  +  N +IY  +Q LL KD+FR++K+N+++ CPFW DD +C    C +  C   E+P GL+  + V +E    K     +     +C D  +  +  +D ++   +K  +     +DD  +D FCEI+D+ ++G  YVDL+KNPER+TGY GKS  R+W SIY+ENCF     K+  N          N  +   CLEKR+FYR+ISGLH++I+I +   Y  K        FGS    W  N   FA RF  K+  +GPQRL+N++F YL+ELRA+ K A YL  + FYTG++V+D ETR AV+  L +++ + NHFDE ++F G    A+ L+ EF  HF NI+RI++CV CDKC+LWG +Q  GMGTALKILF++             + + SSKFQLTR E+VAL  +FGR S+S+  +  F++ M
Sbjct:   28 CFCKGFEAVEPCDCSKPQTIDKLNNHRIYEKVQKLLKKDFFRFYKVNMDKTCPFWADDRQCGTNQCGIAFCD-DEVPAGLRRRNAVNMEAAAVKEEEDDDA---EKCADAGNN-IDPMDRTLHDDEKRQLDAMDHHDDGLEDKFCEIEDDESDGMHYVDLSKNPERYTGYAGKSPQRVWKSIYEENCFKPD-PKFDKNF-------LTNPSNFGMCLEKRVFYRLISGLHSAITISIA-AYNYKPPPPSLGQFGSQMGTWFRNTEMFAGRFGTKWSWEGPQRLRNVYFIYLLELRALLKAAPYLQNELFYTGNDVEDAETRKAVEDLLEEIRAYPNHFDESEMFTGVESHARALREEFRSHFVNISRIMDCVECDKCRLWGKVQTHGMGTALKILFSD--------LPHSHYKQDSSKFQLTRNEVVALLQSFGRYSSSILEVDNFREDM 455
[Close]
BLAST of ERO1-like protein beta vs. Ensembl Celegans
Match: ero-1 (Endoplasmic reticulum oxidoreductin-1 [Source:UniProtKB/Swiss-Prot;Acc:Q7YTU4])

HSP 1 Score: 345.125 bits (884), Expect = 6.791e-112
Identity = 190/450 (42.22%), Postives = 271/450 (60.22%), Query Frame = 1 
Query:  151 CFCKLNESVDDCSC--PVTDLEDYNTKIYPILQSLLVKDYFRYFKINLNRECPFWVDDSRCALRDCHVKGCGPKEIPKGLQEDDPVYIEHQKSKYFGTPNIVHHPECLDENHGGLGNLDISISQTQKEVMHNWTIYDDQ-QDNFCEIDDENANGATYVDLTKNPERFTGYMGKSAHRIWNSIYKENCFNEHRNKYGINLHDAEYLGFLNVIDREQCLEKRIFYRIISGLHTSISIHLCREYLLKDKTG----FGSPQ--WGPNVTEFAKRFDPKFEKDGPQRLKNLFFTYLVELRAIAKVADYLSEDQFYTGDEVDDKETRLAVKHFLTQVKNFTNHFDEQKLFKGDPKEAKKLKHEFVQHFRNITRIINCVGCDKCKLWGTLQVKGMGTALKILFTNPATPEKTSADKDSFTKISSKFQLTRTEIVALFNAFGRLSTSVHSLSLFKDLM 1473
            CFCK  E+V+ C C  P T  +  N +IY  +Q LL KD+FR++K+N+++ CPFW DD +C    C +  C   E+P GL+  + V +E    K     +     +C D  +  +  +D ++   +K  +     +DD  +D FCEI+D+ ++G  YVDL+KNPER+TGY GKS  R+W SIY+ENCF     K+  N          N  +   CLEKR+FYR+ISGLH++I+I +   Y  K        FGS    W  N   FA RF  K+  +GPQRL+N++F YL+ELRA+ K A YL  + FYTG++V+D ETR AV+  L +++ + NHFDE ++F G    A+ L+ EF  HF NI+RI++CV CDKC+LWG +Q  GMGTALKILF++             + + SSKFQLTR E+VAL  +FGR S+S+  +  F++ M
Sbjct:   28 CFCKGFEAVEPCDCSKPQTIDKLNNHRIYEKVQKLLKKDFFRFYKVNMDKTCPFWADDRQCGTNQCGIAFCD-DEVPAGLRRRNAVNMEAAAVKEEEDDDA---EKCADAGNN-IDPMDRTLHDDEKRQLDAMDHHDDGLEDKFCEIEDDESDGMHYVDLSKNPERYTGYAGKSPQRVWKSIYEENCFKPD-PKFDKNF-------LTNPSNFGMCLEKRVFYRLISGLHSAITISIA-AYNYKPPPPSLGQFGSQMGTWFRNTEMFAGRFGTKWSWEGPQRLRNVYFIYLLELRALLKAAPYLQNELFYTGNDVEDAETRKAVEDLLEEIRAYPNHFDESEMFTGVESHARALREEFRSHFVNISRIMDCVECDKCRLWGKVQTHGMGTALKILFSD--------LPHSHYKQDSSKFQLTRNEVVALLQSFGRYSSSILEVDNFREDM 455
[Close]
BLAST of ERO1-like protein beta vs. Ensembl Celegans
Match: ero-1 (Endoplasmic reticulum oxidoreductin-1 [Source:UniProtKB/Swiss-Prot;Acc:Q7YTU4])

HSP 1 Score: 345.125 bits (884), Expect = 6.791e-112
Identity = 190/450 (42.22%), Postives = 271/450 (60.22%), Query Frame = 1 
Query:  151 CFCKLNESVDDCSC--PVTDLEDYNTKIYPILQSLLVKDYFRYFKINLNRECPFWVDDSRCALRDCHVKGCGPKEIPKGLQEDDPVYIEHQKSKYFGTPNIVHHPECLDENHGGLGNLDISISQTQKEVMHNWTIYDDQ-QDNFCEIDDENANGATYVDLTKNPERFTGYMGKSAHRIWNSIYKENCFNEHRNKYGINLHDAEYLGFLNVIDREQCLEKRIFYRIISGLHTSISIHLCREYLLKDKTG----FGSPQ--WGPNVTEFAKRFDPKFEKDGPQRLKNLFFTYLVELRAIAKVADYLSEDQFYTGDEVDDKETRLAVKHFLTQVKNFTNHFDEQKLFKGDPKEAKKLKHEFVQHFRNITRIINCVGCDKCKLWGTLQVKGMGTALKILFTNPATPEKTSADKDSFTKISSKFQLTRTEIVALFNAFGRLSTSVHSLSLFKDLM 1473
            CFCK  E+V+ C C  P T  +  N +IY  +Q LL KD+FR++K+N+++ CPFW DD +C    C +  C   E+P GL+  + V +E    K     +     +C D  +  +  +D ++   +K  +     +DD  +D FCEI+D+ ++G  YVDL+KNPER+TGY GKS  R+W SIY+ENCF     K+  N          N  +   CLEKR+FYR+ISGLH++I+I +   Y  K        FGS    W  N   FA RF  K+  +GPQRL+N++F YL+ELRA+ K A YL  + FYTG++V+D ETR AV+  L +++ + NHFDE ++F G    A+ L+ EF  HF NI+RI++CV CDKC+LWG +Q  GMGTALKILF++             + + SSKFQLTR E+VAL  +FGR S+S+  +  F++ M
Sbjct:   28 CFCKGFEAVEPCDCSKPQTIDKLNNHRIYEKVQKLLKKDFFRFYKVNMDKTCPFWADDRQCGTNQCGIAFCD-DEVPAGLRRRNAVNMEAAAVKEEEDDDA---EKCADAGNN-IDPMDRTLHDDEKRQLDAMDHHDDGLEDKFCEIEDDESDGMHYVDLSKNPERYTGYAGKSPQRVWKSIYEENCFKPD-PKFDKNF-------LTNPSNFGMCLEKRVFYRLISGLHSAITISIA-AYNYKPPPPSLGQFGSQMGTWFRNTEMFAGRFGTKWSWEGPQRLRNVYFIYLLELRALLKAAPYLQNELFYTGNDVEDAETRKAVEDLLEEIRAYPNHFDESEMFTGVESHARALREEFRSHFVNISRIMDCVECDKCRLWGKVQTHGMGTALKILFSD--------LPHSHYKQDSSKFQLTRNEVVALLQSFGRYSSSILEVDNFREDM 455
[Close]
BLAST of ERO1-like protein beta vs. Ensembl Celegans
Match: ero-1 (Endoplasmic reticulum oxidoreductin-1 [Source:UniProtKB/Swiss-Prot;Acc:Q7YTU4])

HSP 1 Score: 343.969 bits (881), Expect = 1.779e-111
Identity = 190/452 (42.04%), Postives = 273/452 (60.40%), Query Frame = 1 
Query:  151 CFCKLNESVDDCSC--PVTDLEDYNTKIYPILQSLLVKDYFRYFKINLNRECPFWVDDSRCALRDCHVKGCGPKEIPKGLQEDDPVYIEHQKSKYFGTPNIVHHPECLDENHGGLGNLDISISQTQKEVMHNWTIYDDQ-QDNFCEIDDENANGATYVDLTKNPERFTGYMGKSAHRIWNSIYKENCFNEHRNKYGINL--HDAEYLGFLNVIDREQCLEKRIFYRIISGLHTSISIHLCREYLLKDKTG----FGSPQ--WGPNVTEFAKRFDPKFEKDGPQRLKNLFFTYLVELRAIAKVADYLSEDQFYTGDEVDDKETRLAVKHFLTQVKNFTNHFDEQKLFKGDPKEAKKLKHEFVQHFRNITRIINCVGCDKCKLWGTLQVKGMGTALKILFTNPATPEKTSADKDSFTKISSKFQLTRTEIVALFNAFGRLSTSVHSLSLFKDLM 1473
            CFCK  E+V+ C C  P T  +  N +IY  +Q LL KD+FR++K+N+++ CPFW DD +C    C +  C   E+P GL+  + V +E    K     +     +C D  +  +  +D ++   +K  +     +DD  +D FCEI+D+ ++G  YVDL+KNPER+TGY GKS  R+W SIY+ENCF     K+  N   + + + G         CLEKR+FYR+ISGLH++I+I +   Y  K        FGS    W  N   FA RF  K+  +GPQRL+N++F YL+ELRA+ K A YL  + FYTG++V+D ETR AV+  L +++ + NHFDE ++F G    A+ L+ EF  HF NI+RI++CV CDKC+LWG +Q  GMGTALKILF++             + + SSKFQLTR E+VAL  +FGR S+S+  +  F++ M
Sbjct:   28 CFCKGFEAVEPCDCSKPQTIDKLNNHRIYEKVQKLLKKDFFRFYKVNMDKTCPFWADDRQCGTNQCGIAFCD-DEVPAGLRRRNAVNMEAAAVKEEEDDDA---EKCADAGNN-IDPMDRTLHDDEKRQLDAMDHHDDGLEDKFCEIEDDESDGMHYVDLSKNPERYTGYAGKSPQRVWKSIYEENCFKPD-PKFDKNFLTNPSNFAGM--------CLEKRVFYRLISGLHSAITISIA-AYNYKPPPPSLGQFGSQMGTWFRNTEMFAGRFGTKWSWEGPQRLRNVYFIYLLELRALLKAAPYLQNELFYTGNDVEDAETRKAVEDLLEEIRAYPNHFDESEMFTGVESHARALREEFRSHFVNISRIMDCVECDKCRLWGKVQTHGMGTALKILFSD--------LPHSHYKQDSSKFQLTRNEVVALLQSFGRYSSSILEVDNFREDM 456
[Close]
BLAST of ERO1-like protein beta vs. Ensembl Celegans
Match: ero-1 (Endoplasmic reticulum oxidoreductin-1 [Source:UniProtKB/Swiss-Prot;Acc:Q7YTU4])

HSP 1 Score: 334.339 bits (856), Expect = 2.534e-107
Identity = 192/481 (39.92%), Postives = 275/481 (57.17%), Query Frame = 1 
Query:  151 CFCKLNESVDDCSC--PVTDLEDYNTKIYPILQSLLVKDYFRYFKINLNRECPFWVDDSRCALRDCHVKGCGPKEIPKGLQEDDPVYI-----------------EHQKSKYFGTPNI---VHHPECLDENH-------GGLGN----LDISISQTQKEVMHNWTIYDDQ-QDNFCEIDDENANGATYVDLTKNPERFTGYMGKSAHRIWNSIYKENCFNEHRNKYGINLHDAEYLGFLNVIDREQCLEKRIFYRIISGLHTSISIHLCREYLLKDKTG----FGSPQ--WGPNVTEFAKRFDPKFEKDGPQRLKNLFFTYLVELRAIAKVADYLSEDQFYTGDEVDDKETRLAVKHFLTQVKNFTNHFDEQKLFKGDPKEAKKLKHEFVQHFRNITRIINCVGCDKCKLWGTLQVKGMGTALKILFTNPATPEKTSADKDSFTKISSKFQLTRTEIVALFNAFGRLSTSVHSLSLFKDLM 1473
            CFCK  E+V+ C C  P T  +  N +IY  +Q LL KD+FR++K+N+++ CPFW DD +C    C +  C   E+P GL+  + V +                  +++ ++  T  I   V     + E            GN    +D ++   +K  +     +DD  +D FCEI+D+ ++G  YVDL+KNPER+TGY GKS  R+W SIY+ENCF     K+  N          N  +   CLEKR+FYR+ISGLH++I+I +   Y  K        FGS    W  N   FA RF  K+  +GPQRL+N++F YL+ELRA+ K A YL  + FYTG++V+D ETR AV+  L +++ + NHFDE ++F G    A+ L+ EF  HF NI+RI++CV CDKC+LWG +Q  GMGTALKILF++             + + SSKFQLTR E+VAL  +FGR S+S+  +  F++ M
Sbjct:   28 CFCKGFEAVEPCDCSKPQTIDKLNNHRIYEKVQKLLKKDFFRFYKVNMDKTCPFWADDRQCGTNQCGIAFCD-DEVPAGLRRRNAVNMVRRSSHESSHEISENHNNNRQQRWNETTKIGVIVQEAAAVKEEEDDDAEKCADAGNNIDPMDRTLHDDEKRQLDAMDHHDDGLEDKFCEIEDDESDGMHYVDLSKNPERYTGYAGKSPQRVWKSIYEENCFKPD-PKFDKNF-------LTNPSNFGMCLEKRVFYRLISGLHSAITISIA-AYNYKPPPPSLGQFGSQMGTWFRNTEMFAGRFGTKWSWEGPQRLRNVYFIYLLELRALLKAAPYLQNELFYTGNDVEDAETRKAVEDLLEEIRAYPNHFDESEMFTGVESHARALREEFRSHFVNISRIMDCVECDKCRLWGKVQTHGMGTALKILFSD--------LPHSHYKQDSSKFQLTRNEVVALLQSFGRYSSSILEVDNFREDM 490
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BLAST of ERO1-like protein beta vs. Ensembl Fly
Match: Ero1L (gene:FBgn0261274 transcript:FBtr0073217)

HSP 1 Score: 405.986 bits (1042), Expect = 2.824e-135
Identity = 217/452 (48.01%), Postives = 295/452 (65.27%), Query Frame = 1 
Query:  151 CFCKLNESVDDCSCPVTDLEDYNT-KIYPILQSLLVKDYFRYFKINLNRECPFWVDDSRCALRDCHVKGCGPKEIPKGLQEDDPVYIEHQKSKYFGTPNIVHHPECLD--ENHGGLGNLDISISQTQKEVMHNWTIYDDQQDNFCEIDDENANGATYVDLTKNPERFTGYMGKSAHRIWNSIYKENCF---NEHRNKYGINLHDAEYLGFLNVIDREQCLEKRIFYRIISGLHTSISIHLCREYLLKDKTGFGSPQ--WGPNVTEFAKRFDPKFEK-DGPQRLKNLFFTYLVELRAIAKVADYLSEDQFYTGDEVDDKETRLAVKHFLTQVKNFTNHFDEQKLFKGDPKEAKKLKHEFVQHFRNITRIINCVGCDKCKLWGTLQVKGMGTALKILFTNPATPEKTSADKDS-FTKISSKFQLTRTEIVALFNAFGRLSTSVHSLSLFKDLMK 1476
            CFC+L  S++DCSC V  ++ +N  KIYP LQSLLVK++FR++K+NL +ECPFW DDSRCA+R C V+ C  + IP+G++ D   + E    KY      V    C D  +    LG LD SIS         W  +D+ +++FC +DD +  G+ YVDL  NPER+TGY G+SAHRIW SIY ENCF   NE  NK+      + Y+  L++  R  CLE+R FYRIISGLH+SI+IHLC +YLL +   F  PQ  WGPNV EF +RF P+    +GP  L+NL+F YL+ELRA+AK A YL  + +YTG   +D E +LA+   L+ ++NF +HFDE  LF  +   + K KH++ + FRNI+RI++CVGCDKCKLWG LQ +G+GTALKIL++        S   D    +    F+L+RTEIVALFNAFGRLS S++ +  F+ +++
Sbjct:   44 CFCELEGSINDCSCDVDTVDHFNNMKIYPRLQSLLVKNFFRFYKVNLRQECPFWPDDSRCAMRFCQVENCEEQAIPQGIK-DKGEHKEKAAFKYTREAQ-VGGSACSDGEDFDSSLGFLDTSISDQAHREFELWAKHDEAEEDFCIVDD-HEEGSQYVDLLLNPERYTGYKGESAHRIWKSIYLENCFGGNNETANKF------SNYVPHLDL--RNVCLEQRAFYRIISGLHSSINIHLCSKYLLSESKDFLDPQGIWGPNVKEFKRRFSPETTSGEGPHWLRNLYFIYLIELRALAKAAPYLRREDYYTGIAEEDDEVKLAINDMLSVIENFQSHFDENALF-SNGIASIKFKHDYKEKFRNISRIMSCVGCDKCKLWGKLQTQGLGTALKILYSEKLNLATESGLWDKPHIEADPIFRLSRTEIVALFNAFGRLSNSIYEMENFRCVLR 483
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BLAST of ERO1-like protein beta vs. Ensembl Zebrafish
Match: ero1b (endoplasmic reticulum oxidoreductase beta [Source:ZFIN;Acc:ZDB-GENE-060929-744])

HSP 1 Score: 390.193 bits (1001), Expect = 2.199e-129
Identity = 207/452 (45.80%), Postives = 281/452 (62.17%), Query Frame = 1 
Query:  160 KLNESVDDCSCPVTDLEDYNT-KIYPILQSLLVKDYFRYFKINLNRECPFWVDDSRCALRDCHVKGCGPKEIPKGLQEDDPVYIEHQKSKYFGTPNIVHHPECLDENHGGLGNLDISISQTQKEVMHNWTIYDDQQDNFCEIDDENANGATYVDLTKNPERFTGYMGKSAHRIWNSIYKENCFNEHR-----NKYGINLHDAEYLGFLNVIDREQCLEKRIFYRIISGLHTSISIHLCREYLLKDKTGFGSPQWGPNVTEFAKRFDPKFEK-DGPQRLKNLFFTYLVELRAIAKVADYLSED--QFYTGDEVDDKETRLAVKHFLTQVKNFTNHFDEQKLFKGDPKEAKKLKHEFVQHFRNITRIINCVGCDKCKLWGTLQVKGMGTALKILFTNPAT---PEKTSADKDSFTKISSKFQLTRTEIVALFNAFGRLSTSVHSLSLFKDLMKD 1479
            +L   +DDC C +  ++ +N  KIYP ++ L  +D+FRY+K+NL R CPFW DDS C+++DCHV+ C   ++P G++  +        +KY    N V      ++ H  LG ++ ++S   KE   +W  +DD QD+FC +DDE +  + YVDL  NPER+TGY G SA R+WNSIY+ENCF         N       D +  GF N ++   CLEKR+FYR+ISGLH+SI+IHLC +YLL +  G+G P WGPNV EF +RFDP   K +G +RLKNL+F YL+ELRA++KVA Y        YTG+  +D  T+  +   L + K F  HFDE  +F G   E+K LK EF  HF+NI+RI++CVGC KC+LWG LQ +G+GTAL+ILF+       PE +          S  FQLTR EIVAL N F RLSTS+  L  F+ L+KD
Sbjct:   26 QLTGVLDDCFCDIESIDVFNNFKIYPHIRKLTERDFFRYYKVNLKRPCPFWPDDSHCSIKDCHVEPCPESKVPVGIKSGN-------YNKYSHAANTVSEMRECEQAHE-LGAINSTLSNQSKEAFADWAHHDDAQDHFCGLDDEMSPESEYVDLLLNPERYTGYKGPSAWRVWNSIYEENCFKPRSVYRPLNPLAPVRGDDDGEGFYNWLE-GLCLEKRVFYRLISGLHSSINIHLCAKYLLDE--GWGKPVWGPNVHEFRQRFDPAETKGEGTRRLKNLYFLYLIELRALSKVAPYFERSFINLYTGNTEEDTSTKQLLLEILNETKAFPMHFDESSMFAGHKIESKTLKEEFRLHFKNISRIMDCVGCSKCRLWGKLQTQGLGTALRILFSEKEIKKLPENSP---------SKGFQLTRQEIVALLNGFSRLSTSIKELHNFRTLLKD 457
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BLAST of ERO1-like protein beta vs. Ensembl Zebrafish
Match: ero1a (endoplasmic reticulum oxidoreductase alpha [Source:NCBI gene;Acc:393321])

HSP 1 Score: 385.571 bits (989), Expect = 1.397e-127
Identity = 208/455 (45.71%), Postives = 281/455 (61.76%), Query Frame = 1 
Query:  136 NAVDRCFCKLNESVDDCSCPVTDLEDYNTK-IYPILQSLLVKDYFRYFKINLNRECPFWVDDSRCALRDCHVKGCGPKEIPKGLQEDDPVYIEHQKSKYFGTPNIVHHPECLDENHGGLGNLDISISQTQKEVMHNWTIYDDQQDNFCEIDDENANGATYVDLTKNPERFTGYMGKSAHRIWNSIYKENCF-----NEHRNKYGINLHDAEYLGFLNVIDREQCLEKRIFYRIISGLHTSISIHLCREYLLKDKTGFGSPQWGPNVTEFAKRFDPKFEK-DGPQRLKNLFFTYLVELRAIAKVADYLSED--QFYTGDEVDDKETRLAVKHFLTQVKNFTNHFDEQKLFKGDPKEAKKLKHEFVQHFRNITRIINCVGCDKCKLWGTLQVKGMGTALKILFTNPATPEKTSADKDSFTKISSKFQLTRTEIVALFNAFGRLSTSVHSLSLFKDLM 1473
            +A  RCFC++  ++DDC+C V  ++ +N K I+P LQ LL  DYFR++K+NLN  CPFW D S+C L+ C VK C P E+P+GL+     Y E                EC  E    LG ++ S+S   ++ +  W  YDD+ D FC +DDE++  + YVDL  NPERFTGY+G  A RIWNSIY+ENCF     N   N    N  D +  GF   ++   C+EKR F+R+ISGLH SI+IHL   YLL D+  F   +WG NV+EF +RFD    K +GP+RL+NL+F YL+ELRA+AK+  Y      Q YTG +  D + +  +   L   K+F  HFDE  LF G+ KEA KLK +F   F+NI+RI++CV C KC+LWG LQ +G+GTALKILF+     E+      + +  +  FQL+R EIV+LFNAFGR+STSV  L  F+ L+
Sbjct:   22 SAAHRCFCQVTGTLDDCACDVETIDKFNNKDIFPKLQKLLSSDYFRFYKVNLNNGCPFWTDHSQCGLKYCAVKPCSPDEVPEGLKSSSYKYSEKASH---------DTEEC--EKAEKLGAVNGSLSDETRQALQEWKKYDDESDRFCMLDDEDSPESQYVDLLLNPERFTGYIGAEAWRIWNSIYEENCFKPYSVNRPLNPLASNSGD-DGQGFYRWLEG-LCVEKRAFFRLISGLHASINIHLSARYLL-DENWF-EMKWGHNVSEFQQRFDEDLTKGEGPKRLRNLYFLYLIELRALAKILPYFERSTFQLYTGQDTQDDQNKKLLLELLHVAKSFPLHFDETALFAGNNKEAMKLKEDFKLTFKNISRIMDCVECFKCRLWGKLQTQGLGTALKILFS-----ERQIEAMPNTSNTNPSFQLSRQEIVSLFNAFGRISTSVRELKNFRSLL 456
[Close]
BLAST of ERO1-like protein beta vs. Ensembl Zebrafish
Match: ero1a (endoplasmic reticulum oxidoreductase alpha [Source:NCBI gene;Acc:393321])

HSP 1 Score: 384.8 bits (987), Expect = 2.971e-127
Identity = 206/454 (45.37%), Postives = 282/454 (62.11%), Query Frame = 1 
Query:  136 NAVDRCFCKLNESVDDCSCPVTDLEDYNTK-IYPILQSLLVKDYFRYFKINLNRECPFWVDDSRCALRDCHVKGCGPKEIPKGLQEDDPVYIEHQKSKYFGTPNIVHHPECLDENHGGLGNLDISISQTQKEVMHNWTIYDDQQDNFCEIDDENANGATYVDLTKNPERFTGYMGKSAHRIWNSIYKENCFNEHRNKYGIN---LHDAEY-LGFLNVIDREQCLEKRIFYRIISGLHTSISIHLCREYLLKDKTGFGSPQWGPNVTEFAKRFDPKFEK-DGPQRLKNLFFTYLVELRAIAKVADYLSED--QFYTGDEVDDKETRLAVKHFLTQVKNFTNHFDEQKLFKGDPKEAKKLKHEFVQHFRNITRIINCVGCDKCKLWGTLQVKGMGTALKILFTNPATPEKTSADKDSFTKISSKFQLTRTEIVALFNAFGRLSTSVHSLSLFKDLM 1473
            +A  RCFC++  ++DDC+C V  ++ +N K I+P LQ LL  DYFR++K+NLN  CPFW D S+C L+ C VK C P E+P+GL+     Y E                EC  E    LG ++ S+S   ++ +  W  YDD+ D FC +DDE++  + YVDL  NPERFTGY+G  A RIWNSIY+ENCF  +     +N    +  E+  GF   ++   C+EKR F+R+ISGLH SI+IHL   YLL D+  F   +WG NV+EF +RFD    K +GP+RL+NL+F YL+ELRA+AK+  Y      Q YTG +  D + +  +   L   K+F  HFDE  LF G+ KEA KLK +F   F+NI+RI++CV C KC+LWG LQ +G+GTALKILF+     E+      + +  +  FQL+R EIV+LFNAFGR+STSV  L  F+ L+
Sbjct:   22 SAAHRCFCQVTGTLDDCACDVETIDKFNNKDIFPKLQKLLSSDYFRFYKVNLNNGCPFWTDHSQCGLKYCAVKPCSPDEVPEGLKSSSYKYSEKASHD---------TEEC--EKAEKLGAVNGSLSDETRQALQEWKKYDDESDRFCMLDDEDSPESQYVDLLLNPERFTGYIGAEAWRIWNSIYEENCFKPYSVNRPLNPLASNSGEHGQGFYRWLEG-LCVEKRAFFRLISGLHASINIHLSARYLL-DENWF-EMKWGHNVSEFQQRFDEDLTKGEGPKRLRNLYFLYLIELRALAKILPYFERSTFQLYTGQDTQDDQNKKLLLELLHVAKSFPLHFDETALFAGNNKEAMKLKEDFKLTFKNISRIMDCVECFKCRLWGKLQTQGLGTALKILFS-----ERQIEAMPNTSNTNPSFQLSRQEIVSLFNAFGRISTSVRELKNFRSLL 456
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BLAST of ERO1-like protein beta vs. Ensembl Zebrafish
Match: ero1a (endoplasmic reticulum oxidoreductase alpha [Source:NCBI gene;Acc:393321])

HSP 1 Score: 383.259 bits (983), Expect = 9.418e-127
Identity = 209/455 (45.93%), Postives = 284/455 (62.42%), Query Frame = 1 
Query:  136 NAVDRCFCKLNESVDDCSCPVTDLEDYNTK-IYPILQSLLVKDYFRYFKINLNRECPFWVDDSRCALRDCHVKGCGPKEIPKGLQEDDPVYIEHQKSKYFGTPNIVHHPECLDENHGGLGNLDISISQTQKEVMHNWTIYDDQQDNFCEIDDENANGATYVDLTKNPERFTGYMGKSAHRIWNSIYKENCF-----NEHRNKYGINLHDAEYLGFLNVIDREQCLEKRIFYRIISGLHTSISIHLCREYLLKDKTGFGSPQWGPNVTEFAKRFDPKFEK-DGPQRLKNLFFTYLVELRAIAKVADYL--SEDQFYTGDEVDDKETRLAVKHFLTQVKNFTNHFDEQKLFKGDPKEAKKLKHEFVQHFRNITRIINCVGCDKCKLWGTLQVKGMGTALKILFTNPATPEKTSADKDSFTKISSKFQLTRTEIVALFNAFGRLSTSVHSLSLFKDLM 1473
            +A  RCFC++  ++DDC+C V  ++ +N K I+P LQ LL  DYFR++K+NLN  CPFW D S+C L+ C VK C P E+P+GL+           S Y  + +     EC  E    LG ++ S+S   ++ +  W  YDD+ D FC +DDE++  + YVDL  NPERFTGY+G  A RIWNSIY+ENCF     N   N    N  D +  GF   ++   C+EKR F+R+ISGLH SI+IHL   YLL D+  F   +WG NV+EF +RFD    K +GP+RL+NL+F YL+ELRA+AK+  Y   S  Q YTG +  D + +  +   L   K+F  HFDE  LF G+ KEA KLK +F   F+NI+RI++CV C KC+LWG LQ +G+GTALKILF+     E+      + +  +  FQL+R EIV+LFNAFGR+STSV  L  F+ L+
Sbjct:   22 SAAHRCFCQVTGTLDDCACDVETIDKFNNKDIFPKLQKLLSSDYFRFYKVNLNNGCPFWTDHSQCGLKYCAVKPCSPDEVPEGLK----------SSSYKASHDT---EEC--EKAEKLGAVNGSLSDETRQALQEWKKYDDESDRFCMLDDEDSPESQYVDLLLNPERFTGYIGAEAWRIWNSIYEENCFKPYSVNRPLNPLASNSGD-DGQGFYRWLEG-LCVEKRAFFRLISGLHASINIHLSARYLL-DENWF-EMKWGHNVSEFQQRFDEDLTKGEGPKRLRNLYFLYLIELRALAKILPYFERSTFQLYTGQDTQDDQNKKLLLELLHVAKSFPLHFDETALFAGNNKEAMKLKEDFKLTFKNISRIMDCVECFKCRLWGKLQTQGLGTALKILFS-----ERQIEAMPNTSNTNPSFQLSRQEIVSLFNAFGRISTSVRELKNFRSLL 452
[Close]
BLAST of ERO1-like protein beta vs. Ensembl Zebrafish
Match: ero1a (endoplasmic reticulum oxidoreductase alpha [Source:NCBI gene;Acc:393321])

HSP 1 Score: 349.747 bits (896), Expect = 2.726e-113
Identity = 189/412 (45.87%), Postives = 252/412 (61.17%), Query Frame = 1 
Query:  136 NAVDRCFCKLNESVDDCSCPVTDLEDYNTK-IYPILQSLLVKDYFRYFKINLNRECPFWVDDSRCALRDCHVKGCGPKEIPKGLQEDDPVYIEHQKSKYFGTPNIVHHPECLDENHGGLGNLDISISQTQKEVMHNWTIYDDQQDNFCEIDDENANGATYVDLTKNPERFTGYMGKSAHRIWNSIYKENCF-----NEHRNKYGINLHDAEYLGFLNVIDREQCLEKRIFYRIISGLHTSISIHLCREYLLKDKTGFGSPQWGPNVTEFAKRFDPKFEK-DGPQRLKNLFFTYLVELRAIAKVADYLSED--QFYTGDEVDDKETRLAVKHFLTQVKNFTNHFDEQKLFKGDPKEAKKLKHEFVQHFRNITRIINCVGCDKCKLWGTLQVKGMGTALKILFTN---PATPEK 1335
            +A  RCFC++  ++DDC+C V  ++ +N K I+P LQ LL  DYFR++K+NLN  CPFW D S+C L+ C VK C P E+P+GL+     Y E                EC  E    LG ++ S+S   ++ +  W  YDD+ D FC +DDE++  + YVDL  NPERFTGY+G  A RIWNSIY+ENCF     N   N    N  D    GF   ++   C+EKR F+R+ISGLH SI+IHL   YLL D+  F   +WG NV+EF +RFD    K +GP+RL+NL+F YL+ELRA+AK+  Y      Q YTG +  D + +  +   L   K+F  HFDE  LF G+ KEA KLK +F   F+NI+RI++CV C KC+LWG LQ +G+GTALKILF+     A P K
Sbjct:   22 SAAHRCFCQVTGTLDDCACDVETIDKFNNKDIFPKLQKLLSSDYFRFYKVNLNNGCPFWTDHSQCGLKYCAVKPCSPDEVPEGLKSSSYKYSEKASHD---------TEEC--EKAEKLGAVNGSLSDETRQALQEWKKYDDESDRFCMLDDEDSPESQYVDLLLNPERFTGYIGAEAWRIWNSIYEENCFKPYSVNRPLNPLASNSGDKGQ-GFYRWLEG-LCVEKRAFFRLISGLHASINIHLSARYLL-DENWF-EMKWGHNVSEFQQRFDEDLTKGEGPKRLRNLYFLYLIELRALAKILPYFERSTFQLYTGQDTQDDQNKKLLLELLHVAKSFPLHFDETALFAGNNKEAMKLKEDFKLTFKNISRIMDCVECFKCRLWGKLQTQGLGTALKILFSERQIEAMPNK 418
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BLAST of ERO1-like protein beta vs. Ensembl Xenopus
Match: ero1b (endoplasmic reticulum oxidoreductase beta [Source:NCBI gene;Acc:100038254])

HSP 1 Score: 398.667 bits (1023), Expect = 2.735e-132
Identity = 211/448 (47.10%), Postives = 285/448 (63.62%), Query Frame = 1 
Query:  151 CFCKLNESVDDCSCPVTDLEDYNT-KIYPILQSLLVKDYFRYFKINLNRECPFWVDDSRCALRDCHVKGCGPKEIPKGLQEDDPVYIEHQKSKYFGTPNIVHHPECLDENHGGLGNLDISISQTQKEVMHNWTIYDDQQDNFCEIDDENANGATYVDLTKNPERFTGYMGKSAHRIWNSIYKENCFNEHRNKYGIN-LHDAEYLGFLNVIDREQCLEKRIFYRIISGLHTSISIHLCREYLLKDKTGFGSPQWGPNVTEFAKRFDPKFEK-DGPQRLKNLFFTYLVELRAIAKVADYLSED--QFYTGDEVDDKETRLAVKHFLTQVKNFTNHFDEQKLFKGDPKEAKKLKHEFVQHFRNITRIINCVGCDKCKLWGTLQVKGMGTALKILFTNPATPEKTSADKDSFTKISSKFQLTRTEIVALFNAFGRLSTSVHSLSLFKDLMKD 1479
            C C L   +DDC C V  ++ +N  KI+P L+ L  +DYFRY+K+NL R CPFW +D  C+++DCHV+ C   ++P G++  +        +KY    N     +   E    LG ++ ++S   KE   +W  YDD QD+FCE+DDE +    YVDL  NPER+TGY G SA R+WNSIY+ENCF        +N L  +    F   ++   CLEKR+FYR+ISGLH SI++HL  +YLL+D   +G+P+WGPN  EF  RF P + K +GP+RLKNL+F YL+ELRA++KVA Y        YTG+  +D ET+  +       K+F  HFDE+ +F G+ KEA+ LK EF  HF+NI+RI++CVGCDKC+LWG LQ +G+GTALKILF+     E  S  ++S +K    FQLTR EIVAL NAFGRLSTS+  L  FK L+ D
Sbjct:   44 CGCHLTGVLDDCFCDVESIDAFNNYKIFPKLKKLQERDYFRYYKVNLKRPCPFWAEDGHCSIKDCHVEPCPESKVPLGIKAGN-------YNKYSLEANSEKDIDAC-EQANKLGAINSTLSNQSKEAFIDWARYDDAQDHFCELDDERSPDVQYVDLLLNPERYTGYKGPSAWRVWNSIYEENCFKPRSVYRPLNPLAPSIRESFYEWLE-GLCLEKRVFYRLISGLHASINLHLSAKYLLED--NWGNPRWGPNTKEFTHRFHPAYTKGEGPRRLKNLYFLYLIELRALSKVASYFERSVVDLYTGNLEEDVETKNLLLSIFIDAKSFPMHFDEKSMFAGNKKEARSLKEEFRLHFKNISRIMDCVGCDKCRLWGKLQTQGLGTALKILFSE---KEIQSLPENSPSK---GFQLTRQEIVALINAFGRLSTSIKELQSFKYLLHD 474
[Close]
BLAST of ERO1-like protein beta vs. Ensembl Xenopus
Match: ero1b (endoplasmic reticulum oxidoreductase beta [Source:NCBI gene;Acc:100038254])

HSP 1 Score: 397.512 bits (1020), Expect = 7.955e-132
Identity = 211/452 (46.68%), Postives = 284/452 (62.83%), Query Frame = 1 
Query:  151 CFCKLNESVDDCSCPVTDLEDYNT-KIYPILQSLLVKDYFRYFKINLNRECPFWVDDSRCALRDCHVKGCGPKEIPKGLQEDDPVYIEHQKSKYFGTPNIVHHPECLDENHGGLGNLDISISQTQKEVMHNWTIYDDQQDNFCEIDDENANGATYVDLTKNPERFTGYMGKSAHRIWNSIYKENCFNEHRNKYGINLHDAEYLG-----FLNVIDREQCLEKRIFYRIISGLHTSISIHLCREYLLKDKTGFGSPQWGPNVTEFAKRFDPKFEK-DGPQRLKNLFFTYLVELRAIAKVADYLSED--QFYTGDEVDDKETRLAVKHFLTQVKNFTNHFDEQKLFKGDPKEAKKLKHEFVQHFRNITRIINCVGCDKCKLWGTLQVKGMGTALKILFTNPATPEKTSADKDSFTKISSKFQLTRTEIVALFNAFGRLSTSVHSLSLFKDLMKD 1479
            C C L   +DDC C V  ++ +N  KI+P L+ L  +DYFRY+K+NL R CPFW +D  C+++DCHV+ C   ++P G++  +        +KY    N     +   E    LG ++ ++S   KE   +W  YDD QD+FCE+DDE +    YVDL  NPER+TGY G SA R+WNSIY+ENCF        +N       G     F   ++   CLEKR+FYR+ISGLH SI++HL  +YLL+D   +G+P+WGPN  EF  RF P + K +GP+RLKNL+F YL+ELRA++KVA Y        YTG+  +D ET+  +       K+F  HFDE+ +F G+ KEA+ LK EF  HF+NI+RI++CVGCDKC+LWG LQ +G+GTALKILF+     E  S  ++S +K    FQLTR EIVAL NAFGRLSTS+  L  FK L+ D
Sbjct:   44 CGCHLTGVLDDCFCDVESIDAFNNYKIFPKLKKLQERDYFRYYKVNLKRPCPFWAEDGHCSIKDCHVEPCPESKVPLGIKAGN-------YNKYSLEANSEKDIDAC-EQANKLGAINSTLSNQSKEAFIDWARYDDAQDHFCELDDERSPDVQYVDLLLNPERYTGYKGPSAWRVWNSIYEENCFKPRSVYRPLNPLAPSISGDTGESFYEWLEG-LCLEKRVFYRLISGLHASINLHLSAKYLLED--NWGNPRWGPNTKEFTHRFHPAYTKGEGPRRLKNLYFLYLIELRALSKVASYFERSVVDLYTGNLEEDVETKNLLLSIFIDAKSFPMHFDEKSMFAGNKKEARSLKEEFRLHFKNISRIMDCVGCDKCRLWGKLQTQGLGTALKILFSE---KEIQSLPENSPSK---GFQLTRQEIVALINAFGRLSTSIKELQSFKYLLHD 478
[Close]
BLAST of ERO1-like protein beta vs. Ensembl Xenopus
Match: ero1a (endoplasmic reticulum oxidoreductase alpha [Source:NCBI gene;Acc:548812])

HSP 1 Score: 394.43 bits (1012), Expect = 1.246e-130
Identity = 216/458 (47.16%), Postives = 280/458 (61.14%), Query Frame = 1 
Query:  133 SNAVDRCFCKLNESVDDCSCPVTDLEDYNT-KIYPILQSLLVKDYFRYFKINLNRECPFWVDDSRCALRDCHVKGCGPKEIPKGLQEDDPVYIEHQKSKYFGTPNIVHHPECLD-ENHGGLGNLDISISQTQKEVMHNWTIYDDQQDNFCEIDDENANGATYVDLTKNPERFTGYMGKSAHRIWNSIYKENCFNEHRNKYGIN-----LHDAEYLGFLNVIDREQCLEKRIFYRIISGLHTSISIHLCREYLLKDKTGFGSPQWGPNVTEFAKRFDPKF-EKDGPQRLKNLFFTYLVELRAIAKVADYLSEDQF--YTGDEVDDKETRLAVKHFLTQVKNFTNHFDEQKLFKGDPKEAKKLKHEFVQHFRNITRIINCVGCDKCKLWGTLQVKGMGTALKILFTNPATPEKTSADKDSFTKISSKFQLTRTEIVALFNAFGRLSTSVHSLSLFKDLMK 1476
            S+A  RCFC++   +DDC+C V  ++ +N   ++P LQ L+  DYFRY+K NL + CPFW D+S C ++DC VK C   E+P GL+     Y E              H E  D E    L  +D S+S   +E M  W  +DD  DNFCE+DDE +  A YVDL KNPER+TGY G    RIWNSIY+ENCF     +  +N       + E   F N +D   C+EKR FYR+ISGLH SI+IHLC  YLLKD   +    WG N  EF KRFD    + +GP+RLKNL+F YL+ELRAI+KV  +     F  YTG+E  D ET+  +   L   ++F  HFDE  LF GD KEA KLK +F QHFRNI++I++CVGC KC+LWG LQ +G+GTALKILF+       + +++       S+F LTR EIVALFNAF R+STSV  L  F+ L++
Sbjct:   35 SSAAQRCFCQVTGYLDDCTCDVETIDHFNNYGLFPKLQQLVASDYFRYYKANLKKPCPFWEDNSHCGVKDCAVKPCPTDEVP-GLKPPGFKYTEEANRA---------HEEIDDCEKEKRLSAVDESLSVEAQEAMLKWNRHDDSADNFCELDDEESPDAEYVDLLKNPERYTGYKGADTWRIWNSIYEENCFKPKAVQRPLNPLTSTRGENEGKVFYNWLDG-LCVEKRAFYRLISGLHASINIHLCANYLLKDT--WMDKIWGHNTAEFQKRFDATLTQGEGPKRLKNLYFIYLIELRAISKVLPFFERSSFLLYTGNETKDTETKKLLLDVLLDARDFPLHFDENSLFSGDKKEAAKLKEDFRQHFRNISKIMDCVGCFKCRLWGKLQTQGLGTALKILFSERQIENLSESNQ------PSEFHLTRQEIVALFNAFARISTSVKELENFRTLLE 473
[Close]
BLAST of ERO1-like protein beta vs. Ensembl Xenopus
Match: ero1a (endoplasmic reticulum oxidoreductase alpha [Source:NCBI gene;Acc:548812])

HSP 1 Score: 393.66 bits (1010), Expect = 1.464e-130
Identity = 213/453 (47.02%), Postives = 276/453 (60.93%), Query Frame = 1 
Query:  133 SNAVDRCFCKLNESVDDCSCPVTDLEDYNT-KIYPILQSLLVKDYFRYFKINLNRECPFWVDDSRCALRDCHVKGCGPKEIPKGLQEDDPVYIEHQKSKYFGTPNIVHHPECLD-ENHGGLGNLDISISQTQKEVMHNWTIYDDQQDNFCEIDDENANGATYVDLTKNPERFTGYMGKSAHRIWNSIYKENCFNEHRNKYGINLHDAEYLGFLNVIDREQCLEKRIFYRIISGLHTSISIHLCREYLLKDKTGFGSPQWGPNVTEFAKRFDPKF-EKDGPQRLKNLFFTYLVELRAIAKVADYLSEDQF--YTGDEVDDKETRLAVKHFLTQVKNFTNHFDEQKLFKGDPKEAKKLKHEFVQHFRNITRIINCVGCDKCKLWGTLQVKGMGTALKILFTNPATPEKTSADKDSFTKISSKFQLTRTEIVALFNAFGRLSTSVHSLSLFKDLMK 1476
            S+A  RCFC++   +DDC+C V  ++ +N   ++P LQ L+  DYFRY+K NL + CPFW D+S C ++DC VK C   E+P GL+     Y E              H E  D E    L  +D S+S   +E M  W  +DD  DNFCE+DDE +  A YVDL KNPER+TGY G    RIWNSIY+ENCF     +  +N   +          R  C+EKR FYR+ISGLH SI+IHLC  YLLKD   +    WG N  EF KRFD    + +GP+RLKNL+F YL+ELRAI+KV  +     F  YTG+E  D ET+  +   L   ++F  HFDE  LF GD KEA KLK +F QHFRNI++I++CVGC KC+LWG LQ +G+GTALKILF+       + +++       S+F LTR EIVALFNAF R+STSV  L  F+ L++
Sbjct:   34 SSAAQRCFCQVTGYLDDCTCDVETIDHFNNYGLFPKLQQLVASDYFRYYKANLKKPCPFWEDNSHCGVKDCAVKPCPTDEVP-GLKPPGFKYTEEANRA---------HEEIDDCEKEKRLSAVDESLSVEAQEAMLKWNRHDDSADNFCELDDEESPDAEYVDLLKNPERYTGYKGADTWRIWNSIYEENCFKPKAVQRPLNPLTS---------TRGLCVEKRAFYRLISGLHASINIHLCANYLLKDT--WMDKIWGHNTAEFQKRFDATLTQGEGPKRLKNLYFIYLIELRAISKVLPFFERSSFLLYTGNETKDTETKKLLLDVLLDARDFPLHFDENSLFSGDKKEAAKLKEDFRQHFRNISKIMDCVGCFKCRLWGKLQTQGLGTALKILFSERQIENLSESNQ------PSEFHLTRQEIVALFNAFARISTSVKELENFRTLLE 459
[Close]
BLAST of ERO1-like protein beta vs. Ensembl Xenopus
Match: ero1a (endoplasmic reticulum oxidoreductase alpha [Source:NCBI gene;Acc:548812])

HSP 1 Score: 388.267 bits (996), Expect = 1.779e-128
Identity = 209/452 (46.24%), Postives = 275/452 (60.84%), Query Frame = 1 
Query:  133 SNAVDRCFCKLNESVDDCSCPVTDLEDYNT-KIYPILQSLLVKDYFRYFKINLNRECPFWVDDSRCALRDCHVKGCGPKEIPKGLQEDDPVYIEHQKSKYFGTPNIVHHPECLDENHGGLGNLDISISQTQKEVMHNWTIYDDQQDNFCEIDDENANGATYVDLTKNPERFTGYMGKSAHRIWNSIYKENCFNEHRNKYGINLHDAEYLGFLNVIDREQCLEKRIFYRIISGLHTSISIHLCREYLLKDKTGFGSPQWGPNVTEFAKRFDPKF-EKDGPQRLKNLFFTYLVELRAIAKVADYLSEDQF--YTGDEVDDKETRLAVKHFLTQVKNFTNHFDEQKLFKGDPKEAKKLKHEFVQHFRNITRIINCVGCDKCKLWGTLQVKGMGTALKILFTNPATPEKTSADKDSFTKISSKFQLTRTEIVALFNAFGRLSTSVHSLSLFKDLMK 1476
            S+A  RCFC++   +DDC+C V  ++ +N   ++P LQ L+  DYFRY+K NL + CPFW D+S C ++DC VK C     P G++     +++     Y    N  H      E    L  +D S+S   +E M  W  +DD  DNFCE+DDE +  A YVDL KNPER+TGY G    RIWNSIY+ENCF     +  +N   +          R  C+EKR FYR+ISGLH SI+IHLC  YLLKD   +    WG N  EF KRFD    + +GP+RLKNL+F YL+ELRAI+KV  +     F  YTG+E  D ET+  +   L   ++F  HFDE  LF GD KEA KLK +F QHFRNI++I++CVGC KC+LWG LQ +G+GTALKILF+       + +++       S+F LTR EIVALFNAF R+STSV  L  F+ L++
Sbjct:   35 SSAAQRCFCQVTGYLDDCTCDVETIDHFNNYGLFPKLQQLVASDYFRYYKANLKKPCPFWEDNSHCGVKDCAVKPC-----PTGVKAYYFYFLQ-----YTEEANRAHEEIDDCEKEKRLSAVDESLSVEAQEAMLKWNRHDDSADNFCELDDEESPDAEYVDLLKNPERYTGYKGADTWRIWNSIYEENCFKPKAVQRPLNPLTS---------TRGLCVEKRAFYRLISGLHASINIHLCANYLLKDT--WMDKIWGHNTAEFQKRFDATLTQGEGPKRLKNLYFIYLIELRAISKVLPFFERSSFLLYTGNETKDTETKKLLLDVLLDARDFPLHFDENSLFSGDKKEAAKLKEDFRQHFRNISKIMDCVGCFKCRLWGKLQTQGLGTALKILFSERQIENLSESNQ------PSEFHLTRQEIVALFNAFARISTSVKELENFRTLLE 459
[Close]
BLAST of ERO1-like protein beta vs. Ensembl Mouse
Match: Ero1lb (ERO1-like beta (S. cerevisiae) [Source:MGI Symbol;Acc:MGI:1914725])

HSP 1 Score: 400.593 bits (1028), Expect = 2.523e-133
Identity = 209/448 (46.65%), Postives = 281/448 (62.72%), Query Frame = 1 
Query:  175 VDDCSCPVTDLEDYNT-KIYPILQSLLVKDYFRYFKINLNRECPFWVDDSRCALRDCHVKGCGPKEIPKGLQEDDPVYIEHQKSKYFGTPNIVHHPECLD--ENHGGLGNLDISISQTQKEVMHNWTIYDDQQDNFCEIDDENANGATYVDLTKNPERFTGYMGKSAHRIWNSIYKENCFNEHR-----NKYGINLHDAEYLGFLNVIDREQCLEKRIFYRIISGLHTSISIHLCREYLLKDKTGFGSPQWGPNVTEFAKRFDPKFEK-DGPQRLKNLFFTYLVELRAIAKVADYLSED--QFYTGDEVDDKETRLAVKHFLTQVKNFTNHFDEQKLFKGDPKEAKKLKHEFVQHFRNITRIINCVGCDKCKLWGTLQVKGMGTALKILFTNPAT---PEKTSADKDSFTKISSKFQLTRTEIVALFNAFGRLSTSVHSLSLFKDLMK 1476
            +DDC C +  ++ +NT KI+P ++ L  +DYFRY+K+NL R CPFW +D  C+++DCHV+ C   +IP G++         + +KY    N       LD  E    LG ++ ++S   KE   +W  YDD QD+FCE+DDE +  A YVDL  NPER+TGY G SA R+WNSIY+ENCF         N    +  + +   F   ++   CLEKR+FY++ISGLH SI++HLC  YLL++   +G P WGPN+ EF +RFDP   K +GP+RLKNL+F YL+ELRA++KVA Y        YTG+  DD +T+  +       K+F  HFDE+ +F GD K AK LK EF  HF+NI+RI++CVGCDKC+LWG LQ +G+GTALKILF+       PE +          S  FQLTR EIVAL NAFGRLSTS+  L  FK L++
Sbjct:   39 LDDCLCDIDSIDKFNTYKIFPKIKKLQERDYFRYYKVNLKRPCPFWAEDGHCSIKDCHVEPCPESKIPVGIKAG-------RSNKYSQAANSTKE---LDDCEQANKLGAINSTLSNESKEAFIDWARYDDSQDHFCELDDERSPAAQYVDLLLNPERYTGYKGSSAWRVWNSIYEENCFKPRSVYRPLNPLAPSRGEDDGESFYTWLE-GLCLEKRVFYKLISGLHASINLHLCANYLLEET--WGKPSWGPNIKEFRRRFDPVETKGEGPRRLKNLYFLYLIELRALSKVAPYFERSIVDLYTGNVEDDADTKTLLLSIFQDTKSFPMHFDEKSMFAGDKKGAKSLKEEFRLHFKNISRIMDCVGCDKCRLWGKLQTQGLGTALKILFSEKEIQNLPENSP---------SKGFQLTRQEIVALLNAFGRLSTSIRELQNFKALLQ 464
[Close]
BLAST of ERO1-like protein beta vs. Ensembl Mouse
Match: Ero1lb (ERO1-like beta (S. cerevisiae) [Source:MGI Symbol;Acc:MGI:1914725])

HSP 1 Score: 387.111 bits (993), Expect = 7.683e-128
Identity = 202/434 (46.54%), Postives = 271/434 (62.44%), Query Frame = 1 
Query:  175 VDDCSCPVTDLEDYNT-KIYPILQSLLVKDYFRYFKINLNRECPFWVDDSRCALRDCHVKGCGPKEIPKGLQEDDPVYIEHQKSKYFGTPNIVHHPECLD--ENHGGLGNLDISISQTQKEVMHNWTIYDDQQDNFCEIDDENANGATYVDLTKNPERFTGYMGKSAHRIWNSIYKENCFNEHR-----NKYGINLHDAEYLGFLNVIDREQCLEKRIFYRIISGLHTSISIHLCREYLLKDKTGFGSPQWGPNVTEFAKRFDPKFEK-DGPQRLKNLFFTYLVELRAIAKVADYLSED--QFYTGDEVDDKETRLAVKHFLTQVKNFTNHFDEQKLFKGDPKEAKKLKHEFVQHFRNITRIINCVGCDKCKLWGTLQVKGMGTALKILFTNPAT---PEKTSADKDSFTKISSKFQLTRTEIVALFNAFGRLS 1434
            +DDC C +  ++ +NT KI+P ++ L  +DYFRY+K+NL R CPFW +D  C+++DCHV+ C   +IP G++         + +KY    N       LD  E    LG ++ ++S   KE   +W  YDD QD+FCE+DDE +  A YVDL  NPER+TGY G SA R+WNSIY+ENCF         N    +  + +   F   ++   CLEKR+FY++ISGLH SI++HLC  YLL++   +G P WGPN+ EF +RFDP   K +GP+RLKNL+F YL+ELRA++KVA Y        YTG+  DD +T+  +       K+F  HFDE+ +F GD K AK LK EF  HF+NI+RI++CVGCDKC+LWG LQ +G+GTALKILF+       PE +          S  FQLTR EIVAL NAFGR S
Sbjct:   39 LDDCLCDIDSIDKFNTYKIFPKIKKLQERDYFRYYKVNLKRPCPFWAEDGHCSIKDCHVEPCPESKIPVGIKAG-------RSNKYSQAANSTKE---LDDCEQANKLGAINSTLSNESKEAFIDWARYDDSQDHFCELDDERSPAAQYVDLLLNPERYTGYKGSSAWRVWNSIYEENCFKPRSVYRPLNPLAPSRGEDDGESFYTWLE-GLCLEKRVFYKLISGLHASINLHLCANYLLEET--WGKPSWGPNIKEFRRRFDPVETKGEGPRRLKNLYFLYLIELRALSKVAPYFERSIVDLYTGNVEDDADTKTLLLSIFQDTKSFPMHFDEKSMFAGDKKGAKSLKEEFRLHFKNISRIMDCVGCDKCRLWGKLQTQGLGTALKILFSEKEIQNLPENSP---------SKGFQLTRQEIVALLNAFGRAS 450
[Close]
BLAST of ERO1-like protein beta vs. Ensembl Mouse
Match: Ero1lb (ERO1-like beta (S. cerevisiae) [Source:MGI Symbol;Acc:MGI:1914725])

HSP 1 Score: 386.726 bits (992), Expect = 1.735e-127
Identity = 202/440 (45.91%), Postives = 273/440 (62.05%), Query Frame = 1 
Query:  175 VDDCSCPVTDLEDYNT-KIYPILQSLLVKDYFRYFKINLNRECPFWVDDSRCALRDCHVKGCGPKEIPKGLQEDDPVYIEHQKSKYFGTPNIVHHPECLD--ENHGGLGNLDISISQTQKEVMHNWTIYDDQQDNFCEIDDENANGATYVDLTKNPERFTGYMGKSAHRIWNSIYKENCFNEHR-----NKYGINLHDAEYLGFLNVIDREQCLEKRIFYRIISGLHTSISIHLCREYLLKDKTGFGSPQWGPNVTEFAKRFDPKFEK-DGPQRLKNLFFTYLVELRAIAKVADYLSED--QFYTGDEVDDKETRLAVKHFLTQVKNFTNHFDEQKLFKGDPKEAKKLKHEFVQHFRNITRIINCVGCDKCKLWGTLQVKGMGTALKILFTNPAT---PEKTSADKDSFTKISSKFQLTRTEIVALFNAFGRLSTSVHSL 1452
            +DDC C +  ++ +NT KI+P ++ L  +DYFRY+K+NL R CPFW +D  C+++DCHV+ C   +IP G++         + +KY    N       LD  E    LG ++ ++S   KE   +W  YDD QD+FCE+DDE +  A YVDL  NPER+TGY G SA R+WNSIY+ENCF         N    +  + +   F   ++   CLEKR+FY++ISGLH SI++HLC  YLL++   +G P WGPN+ EF +RFDP   K +GP+RLKNL+F YL+ELRA++KVA Y        YTG+  DD +T+  +       K+F  HFDE+ +F GD K AK LK EF  HF+NI+RI++CVGCDKC+LWG LQ +G+GTALKILF+       PE +          S  FQLTR EIVAL NAFG LS  +  +
Sbjct:   39 LDDCLCDIDSIDKFNTYKIFPKIKKLQERDYFRYYKVNLKRPCPFWAEDGHCSIKDCHVEPCPESKIPVGIKAG-------RSNKYSQAANSTKE---LDDCEQANKLGAINSTLSNESKEAFIDWARYDDSQDHFCELDDERSPAAQYVDLLLNPERYTGYKGSSAWRVWNSIYEENCFKPRSVYRPLNPLAPSRGEDDGESFYTWLE-GLCLEKRVFYKLISGLHASINLHLCANYLLEET--WGKPSWGPNIKEFRRRFDPVETKGEGPRRLKNLYFLYLIELRALSKVAPYFERSIVDLYTGNVEDDADTKTLLLSIFQDTKSFPMHFDEKSMFAGDKKGAKSLKEEFRLHFKNISRIMDCVGCDKCRLWGKLQTQGLGTALKILFSEKEIQNLPENSP---------SKGFQLTRQEIVALLNAFGSLSLCLEPI 456
[Close]
BLAST of ERO1-like protein beta vs. Ensembl Mouse
Match: Ero1l (ERO1-like (S. cerevisiae) [Source:MGI Symbol;Acc:MGI:1354385])

HSP 1 Score: 383.259 bits (983), Expect = 1.168e-126
Identity = 208/453 (45.92%), Postives = 285/453 (62.91%), Query Frame = 1 
Query:  139 AVDRCFCKLNESVDDCSCPVTDLEDYNT-KIYPILQSLLVKDYFRYFKINLNRECPFWVDDSRCALRDCHVKGCGPKEIPKGLQEDDPVYIEHQKSKYFGTPNIVHHPECLDENHGGLGNLDISISQTQKEVMHNWTIYDDQQDNFCEIDDENANGATYVDLTKNPERFTGYMGKSAHRIWNSIYKENCFNEH--RNKYGINLHDAEYLGFLNVIDREQCLEKRIFYRIISGLHTSISIHLCREYLLKDKTGFGSPQWGPNVTEFAKRFDPKF-EKDGPQRLKNLFFTYLVELRAIAKVADYLSED--QFYTGDEVDDKETRLAVKHFLTQVKNFTNHFDEQKLFKGDPKEAKKLKHEFVQHFRNITRIINCVGCDKCKLWGTLQVKGMGTALKILFTNPATPEKTSADKDSFTKISSKFQLTRTEIVALFNAFGRLSTSVHSLSLFKDLMKD 1479
            A  RCFC+++  +DDC+C V  ++ +N  +++P LQ LL  DYFRY+K+NL + CPFW D ++C  RDC VK C   E+P G        I+    KY    N +   EC  E    LG +D S+S+  ++ +  WT +DD  D+FCEIDD  +  A YVDL  NPER+TGY G  A RIW+ IY+ENCF     +         ++   F N ++   C+EKR FYR+ISGLH SI++HL   YLL+D   +   +WG NVTEF +RFD    E +GP+RL+NL+F YL+ELRA++KV  +      Q +TG++V D E +  +   L ++K+F  HFDE   F GD  EA KLK +F  HFRNI+RI++CVGC KC+LWG LQ +G+GTALKILF+     EK  A+    +  S +FQLTR EIV+LFNAFGR+STSV  L  F+ L+++
Sbjct:   31 AAQRCFCQVSGYLDDCTCDVETIDKFNNYRLFPRLQKLLESDYFRYYKVNLKKPCPFWNDINQCGRRDCAVKPCHSDEVPDG--------IKSASYKYSEEANRIE--EC--EQAERLGAVDESLSEETQKAVLQWTKHDDSSDSFCEIDDIQSPDAEYVDLLLNPERYTGYKGPDAWRIWSVIYEENCFKPQTIQRPLASGRGKSKENTFYNWLE-GLCVEKRAFYRLISGLHASINVHLSARYLLQDT--WLEKKWGHNVTEFQQRFDGILTEGEGPRRLRNLYFLYLIELRALSKVLPFFERPDFQLFTGNKVQDAENKALLLEILHEIKSFPLHFDENSFFAGDKNEAHKLKEDFRLHFRNISRIMDCVGCFKCRLWGKLQTQGLGTALKILFS-----EKLIANMPE-SGPSYEFQLTRQEIVSLFNAFGRISTSVRELENFRHLLQN 462
[Close]
BLAST of ERO1-like protein beta vs. Ensembl Mouse
Match: Ero1l (ERO1-like (S. cerevisiae) [Source:MGI Symbol;Acc:MGI:1354385])

HSP 1 Score: 213.772 bits (543), Expect = 1.406e-64
Identity = 112/215 (52.09%), Postives = 148/215 (68.84%), Query Frame = 1 
Query:  787 CLEKRIFYRIISGLHTSISIHLCREYLLKDKTGFGSPQWGPNVTEFAKRFDPKF-EKDGPQRLKNLFFTYLVELRAIAKVADYLSED--QFYTGDEVDDKETRLAVKHFLTQVKNFTNHFDEQKLFKGDPKEAKKLKHEFVQHFRNITRIINCVGCDKCKLWGTLQVKGMGTALKILFTNPATPEKTSADKDSFTKISSKFQLTRTEIVALFNAF 1422
            C+EKR FYR+ISGLH SI++HL   YLL+D   +   +WG NVTEF +RFD    E +GP+RL+NL+F YL+ELRA++KV  +      Q +TG++V D E +  +   L ++K+F  HFDE   F GD  EA KLK +F  HFRNI+RI++CVGC KC+LWG LQ +G+GTALKILF+     EK  A+    +  S +FQLTR EIV+LFNAF
Sbjct:   23 CVEKRAFYRLISGLHASINVHLSARYLLQDT--WLEKKWGHNVTEFQQRFDGILTEGEGPRRLRNLYFLYLIELRALSKVLPFFERPDFQLFTGNKVQDAENKALLLEILHEIKSFPLHFDENSFFAGDKNEAHKLKEDFRLHFRNISRIMDCVGCFKCRLWGKLQTQGLGTALKILFS-----EKLIANMPE-SGPSYEFQLTRQEIVSLFNAF 229
[Close]
BLAST of ERO1-like protein beta vs. UniProt/SwissProt
Match: sp|Q6DD71|ERO1A_XENLA (ERO1-like protein alpha OS=Xenopus laevis OX=8355 GN=ero1a PE=2 SV=1)

HSP 1 Score: 409.453 bits (1051), Expect = 5.970e-136
Identity = 221/478 (46.23%), Postives = 292/478 (61.09%), Query Frame = 1 
Query:   70 YMNLKYIFLLYILSLTLKDCISNAVDRCFCKLNESVDDCSCPVTDLEDYNTK-IYPILQSLLVKDYFRYFKINLNRECPFWVDDSRCALRDCHVKGCGPKEIPKGLQEDDPVYIEHQKSKYFGTPNIVHHPECLDENHGGLGNLDISISQTQKEVMHNWTIYDDQQDNFCEIDDENANGATYVDLTKNPERFTGYMGKSAHRIWNSIYKENCFNEHRNKYGIN-----LHDAEYLGFLNVIDREQCLEKRIFYRIISGLHTSISIHLCREYLLKDKTGFGSPQWGPNVTEFAKRFDPKF-EKDGPQRLKNLFFTYLVELRAIAKVADYLSEDQF--YTGDEVDDKETRLAVKHFLTQVKNFTNHFDEQKLFKGDPKEAKKLKHEFVQHFRNITRIINCVGCDKCKLWGTLQVKGMGTALKILFTNPATPEKTSADKDSFTKISSKFQLTRTEIVALFNAFGRLSTSVHSLSLFKDLMK 1476
            Y ++ ++F L +     ++  ++A  RCFC++   +DDC+C V  ++ +N   ++P LQ L+  DYFRY+K+NL + CPFW D+S C +RDC V  C   E+P G +   P +      KY    N VH      E    L  +D S+S   +E M  W  +DD  DNFCE+DDE +  A YVDL KNPERFTGY G    RIWNSIY+ENCF     +  +N       + E   F N +D   C+EKR FYR+ISGLH SI+IHLC  YLLKD   +    WG NV EF KRFD      +GP+RL+NL+F YL+ELRAI+KV  +     F  YTG+E  DKET+  +   L   ++F  HFDE  LF GD KEA KLK +F QHFRNI++I++CVGC KC+LWG LQ +G+GTALKILF+       + +++       S F LTR EIVALFNAFGR+STSV  L  F+ L++
Sbjct:    4 YGSVLFLFSLLVWGTIAQEAPASAAQRCFCQVTGYLDDCTCDVETIDRFNNHGLFPKLQQLVASDYFRYYKVNLKKSCPFWEDNSHCGVRDCAVNPCSSDEVP-GFKP--PGF------KYTEEANHVHEDVDDCEKEKRLSAVDESLSVETQEAMLKWNRHDDSSDNFCEVDDEESPDAEYVDLLKNPERFTGYKGADTWRIWNSIYEENCFKPKAVQRPLNPLTSSRGENEGNMFYNWLDG-LCVEKRAFYRLISGLHASINIHLCATYLLKDT--WMDKIWGHNVAEFQKRFDATLTHGEGPKRLRNLYFIYLIELRAISKVLPFFERSNFLLYTGNETKDKETKKILLDVLQDARDFPLHFDENSLFSGDKKEAAKLKEDFRQHFRNISKIMDCVGCFKCRLWGKLQTQGLGTALKILFSEKQIENLSESNQ------PSAFHLTRQEIVALFNAFGRISTSVQELENFRKLLE 463
[Close]
BLAST of ERO1-like protein beta vs. UniProt/SwissProt
Match: sp|Q9V3A6|ERO1L_DROME (Ero1-like protein OS=Drosophila melanogaster OX=7227 GN=Ero1L PE=2 SV=2)

HSP 1 Score: 405.986 bits (1042), Expect = 2.831e-134
Identity = 217/452 (48.01%), Postives = 295/452 (65.27%), Query Frame = 1 
Query:  151 CFCKLNESVDDCSCPVTDLEDYNT-KIYPILQSLLVKDYFRYFKINLNRECPFWVDDSRCALRDCHVKGCGPKEIPKGLQEDDPVYIEHQKSKYFGTPNIVHHPECLD--ENHGGLGNLDISISQTQKEVMHNWTIYDDQQDNFCEIDDENANGATYVDLTKNPERFTGYMGKSAHRIWNSIYKENCF---NEHRNKYGINLHDAEYLGFLNVIDREQCLEKRIFYRIISGLHTSISIHLCREYLLKDKTGFGSPQ--WGPNVTEFAKRFDPKFEK-DGPQRLKNLFFTYLVELRAIAKVADYLSEDQFYTGDEVDDKETRLAVKHFLTQVKNFTNHFDEQKLFKGDPKEAKKLKHEFVQHFRNITRIINCVGCDKCKLWGTLQVKGMGTALKILFTNPATPEKTSADKDS-FTKISSKFQLTRTEIVALFNAFGRLSTSVHSLSLFKDLMK 1476
            CFC+L  S++DCSC V  ++ +N  KIYP LQSLLVK++FR++K+NL +ECPFW DDSRCA+R C V+ C  + IP+G++ D   + E    KY      V    C D  +    LG LD SIS         W  +D+ +++FC +DD +  G+ YVDL  NPER+TGY G+SAHRIW SIY ENCF   NE  NK+      + Y+  L++  R  CLE+R FYRIISGLH+SI+IHLC +YLL +   F  PQ  WGPNV EF +RF P+    +GP  L+NL+F YL+ELRA+AK A YL  + +YTG   +D E +LA+   L+ ++NF +HFDE  LF  +   + K KH++ + FRNI+RI++CVGCDKCKLWG LQ +G+GTALKIL++        S   D    +    F+L+RTEIVALFNAFGRLS S++ +  F+ +++
Sbjct:   44 CFCELEGSINDCSCDVDTVDHFNNMKIYPRLQSLLVKNFFRFYKVNLRQECPFWPDDSRCAMRFCQVENCEEQAIPQGIK-DKGEHKEKAAFKYTREAQ-VGGSACSDGEDFDSSLGFLDTSISDQAHREFELWAKHDEAEEDFCIVDD-HEEGSQYVDLLLNPERYTGYKGESAHRIWKSIYLENCFGGNNETANKF------SNYVPHLDL--RNVCLEQRAFYRIISGLHSSINIHLCSKYLLSESKDFLDPQGIWGPNVKEFKRRFSPETTSGEGPHWLRNLYFIYLIELRALAKAAPYLRREDYYTGIAEEDDEVKLAINDMLSVIENFQSHFDENALF-SNGIASIKFKHDYKEKFRNISRIMSCVGCDKCKLWGKLQTQGLGTALKILYSEKLNLATESGLWDKPHIEADPIFRLSRTEIVALFNAFGRLSNSIYEMENFRCVLR 483
[Close]
BLAST of ERO1-like protein beta vs. UniProt/SwissProt
Match: sp|Q8R2E9|ERO1B_MOUSE (ERO1-like protein beta OS=Mus musculus OX=10090 GN=Ero1b PE=1 SV=1)

HSP 1 Score: 400.593 bits (1028), Expect = 1.765e-132
Identity = 209/448 (46.65%), Postives = 281/448 (62.72%), Query Frame = 1 
Query:  175 VDDCSCPVTDLEDYNT-KIYPILQSLLVKDYFRYFKINLNRECPFWVDDSRCALRDCHVKGCGPKEIPKGLQEDDPVYIEHQKSKYFGTPNIVHHPECLD--ENHGGLGNLDISISQTQKEVMHNWTIYDDQQDNFCEIDDENANGATYVDLTKNPERFTGYMGKSAHRIWNSIYKENCFNEHR-----NKYGINLHDAEYLGFLNVIDREQCLEKRIFYRIISGLHTSISIHLCREYLLKDKTGFGSPQWGPNVTEFAKRFDPKFEK-DGPQRLKNLFFTYLVELRAIAKVADYLSED--QFYTGDEVDDKETRLAVKHFLTQVKNFTNHFDEQKLFKGDPKEAKKLKHEFVQHFRNITRIINCVGCDKCKLWGTLQVKGMGTALKILFTNPAT---PEKTSADKDSFTKISSKFQLTRTEIVALFNAFGRLSTSVHSLSLFKDLMK 1476
            +DDC C +  ++ +NT KI+P ++ L  +DYFRY+K+NL R CPFW +D  C+++DCHV+ C   +IP G++         + +KY    N       LD  E    LG ++ ++S   KE   +W  YDD QD+FCE+DDE +  A YVDL  NPER+TGY G SA R+WNSIY+ENCF         N    +  + +   F   ++   CLEKR+FY++ISGLH SI++HLC  YLL++   +G P WGPN+ EF +RFDP   K +GP+RLKNL+F YL+ELRA++KVA Y        YTG+  DD +T+  +       K+F  HFDE+ +F GD K AK LK EF  HF+NI+RI++CVGCDKC+LWG LQ +G+GTALKILF+       PE +          S  FQLTR EIVAL NAFGRLSTS+  L  FK L++
Sbjct:   39 LDDCLCDIDSIDKFNTYKIFPKIKKLQERDYFRYYKVNLKRPCPFWAEDGHCSIKDCHVEPCPESKIPVGIKAG-------RSNKYSQAANSTKE---LDDCEQANKLGAINSTLSNESKEAFIDWARYDDSQDHFCELDDERSPAAQYVDLLLNPERYTGYKGSSAWRVWNSIYEENCFKPRSVYRPLNPLAPSRGEDDGESFYTWLE-GLCLEKRVFYKLISGLHASINLHLCANYLLEET--WGKPSWGPNIKEFRRRFDPVETKGEGPRRLKNLYFLYLIELRALSKVAPYFERSIVDLYTGNVEDDADTKTLLLSIFQDTKSFPMHFDEKSMFAGDKKGAKSLKEEFRLHFKNISRIMDCVGCDKCRLWGKLQTQGLGTALKILFSEKEIQNLPENSP---------SKGFQLTRQEIVALLNAFGRLSTSIRELQNFKALLQ 464
[Close]
BLAST of ERO1-like protein beta vs. UniProt/SwissProt
Match: sp|Q86YB8|ERO1B_HUMAN (ERO1-like protein beta OS=Homo sapiens OX=9606 GN=ERO1B PE=1 SV=2)

HSP 1 Score: 397.127 bits (1019), Expect = 4.645e-131
Identity = 207/447 (46.31%), Postives = 281/447 (62.86%), Query Frame = 1 
Query:  175 VDDCSCPVTDLEDYNT-KIYPILQSLLVKDYFRYFKINLNRECPFWVDDSRCALRDCHVKGCGPKEIPKGLQEDDPVYIEHQKSKYFGTPNIVHHPE-CLDENHGGLGNLDISISQTQKEVMHNWTIYDDQQDNFCEIDDENANGATYVDLTKNPERFTGYMGKSAHRIWNSIYKENCFNEHR-----NKYGINLHDAEYLGFLNVIDREQCLEKRIFYRIISGLHTSISIHLCREYLLKDKTGFGSPQWGPNVTEFAKRFDPKFEK-DGPQRLKNLFFTYLVELRAIAKVADYLSED--QFYTGDEVDDKETRLAVKHFLTQVKNFTNHFDEQKLFKGDPKEAKKLKHEFVQHFRNITRIINCVGCDKCKLWGTLQVKGMGTALKILFTNPAT---PEKTSADKDSFTKISSKFQLTRTEIVALFNAFGRLSTSVHSLSLFKDLMK 1476
            +DDC C +  ++++NT KI+P ++ L  +DYFRY+K+NL R CPFW +D  C+++DCHV+ C   +IP G++           +KY    N     E C  E    LG ++ ++S   KE   +W  YDD +D+FCE+DDE +  A YVDL  NPER+TGY G SA R+WNSIY+ENCF         N    +  + +   F   ++   CLEKR+FY++ISGLH SI++HLC  YLL++   +G P WGPN+ EF  RFDP   K +GP+RLKNL+F YL+ELRA++KVA Y        YTG+  +D +T+  + +     K+F  HFDE+ +F GD K AK LK EF  HF+NI+RI++CVGCDKC+LWG LQ +G+GTALKILF+       PE +          S  FQLTR EIVAL NAFGRLSTS+  L  FK L++
Sbjct:   39 LDDCLCDIDSIDNFNTYKIFPKIKKLQERDYFRYYKVNLKRPCPFWAEDGHCSIKDCHVEPCPESKIPVGIKAG-------HSNKYLKMANNTKELEDC--EQANKLGAINSTLSNQSKEAFIDWARYDDSRDHFCELDDERSPAAQYVDLLLNPERYTGYKGTSAWRVWNSIYEENCFKPRSVYRPLNPLAPSRGEDDGESFYTWLE-GLCLEKRVFYKLISGLHASINLHLCANYLLEET--WGKPSWGPNIKEFKHRFDPVETKGEGPRRLKNLYFLYLIELRALSKVAPYFERSIVDLYTGNAEEDADTKTLLLNIFQDTKSFPMHFDEKSMFAGDKKGAKSLKEEFRLHFKNISRIMDCVGCDKCRLWGKLQTQGLGTALKILFSEKEIQKLPENSP---------SKGFQLTRQEIVALLNAFGRLSTSIRDLQNFKVLLQ 464
[Close]
BLAST of ERO1-like protein beta vs. UniProt/SwissProt
Match: sp|B1H1F9|ERO1A_XENTR (ERO1-like protein alpha OS=Xenopus tropicalis OX=8364 GN=ero1a PE=2 SV=1)

HSP 1 Score: 394.43 bits (1012), Expect = 6.600e-130
Identity = 216/458 (47.16%), Postives = 280/458 (61.14%), Query Frame = 1 
Query:  133 SNAVDRCFCKLNESVDDCSCPVTDLEDYNT-KIYPILQSLLVKDYFRYFKINLNRECPFWVDDSRCALRDCHVKGCGPKEIPKGLQEDDPVYIEHQKSKYFGTPNIVHHPECLD-ENHGGLGNLDISISQTQKEVMHNWTIYDDQQDNFCEIDDENANGATYVDLTKNPERFTGYMGKSAHRIWNSIYKENCFNEHRNKYGIN-----LHDAEYLGFLNVIDREQCLEKRIFYRIISGLHTSISIHLCREYLLKDKTGFGSPQWGPNVTEFAKRFDPKF-EKDGPQRLKNLFFTYLVELRAIAKVADYLSEDQF--YTGDEVDDKETRLAVKHFLTQVKNFTNHFDEQKLFKGDPKEAKKLKHEFVQHFRNITRIINCVGCDKCKLWGTLQVKGMGTALKILFTNPATPEKTSADKDSFTKISSKFQLTRTEIVALFNAFGRLSTSVHSLSLFKDLMK 1476
            S+A  RCFC++   +DDC+C V  ++ +N   ++P LQ L+  DYFRY+K NL + CPFW D+S C ++DC VK C   E+P GL+     Y E              H E  D E    L  +D S+S   +E M  W  +DD  DNFCE+DDE +  A YVDL KNPER+TGY G    RIWNSIY+ENCF     +  +N       + E   F N +D   C+EKR FYR+ISGLH SI+IHLC  YLLKD   +    WG N  EF KRFD    + +GP+RLKNL+F YL+ELRAI+KV  +     F  YTG+E  D ET+  +   L   ++F  HFDE  LF GD KEA KLK +F QHFRNI++I++CVGC KC+LWG LQ +G+GTALKILF+       + +++       S+F LTR EIVALFNAF R+STSV  L  F+ L++
Sbjct:   34 SSAAQRCFCQVTGYLDDCTCDVETIDHFNNYGLFPKLQQLVASDYFRYYKANLKKPCPFWEDNSHCGVKDCAVKPCPTDEVP-GLKPPGFKYTEEANRA---------HEEIDDCEKEKRLSAVDESLSVEAQEAMLKWNRHDDSADNFCELDDEESPDAEYVDLLKNPERYTGYKGADTWRIWNSIYEENCFKPKAVQRPLNPLTSTRGENEGKVFYNWLDG-LCVEKRAFYRLISGLHASINIHLCANYLLKDT--WMDKIWGHNTAEFQKRFDATLTQGEGPKRLKNLYFIYLIELRAISKVLPFFERSSFLLYTGNETKDTETKKLLLDVLLDARDFPLHFDENSLFSGDKKEAAKLKEDFRQHFRNISKIMDCVGCFKCRLWGKLQTQGLGTALKILFSERQIENLSESNQ------PSEFHLTRQEIVALFNAFARISTSVKELENFRTLLE 472
[Close]
BLAST of ERO1-like protein beta vs. TrEMBL
Match: A0A2C9KB75 (Uncharacterized protein OS=Biomphalaria glabrata OX=6526 GN=106055939 PE=4 SV=1)

HSP 1 Score: 474.552 bits (1220), Expect = 8.102e-159
Identity = 247/474 (52.11%), Postives = 311/474 (65.61%), Query Frame = 1 
Query:   79 LKYIFLLYILSLTLKDCIS---NAVDRCFCKLNESVDDCSCPVTDLEDYNT-KIYPILQSLLVKDYFRYFKINLNRECPFWVDDSRCALRDCHVKGCGPKEIPKGLQEDDPVYIEHQKSKYFGTPNIVHH---PECLDENHGGLGNLDISISQTQKEVMHNWTIYDDQQDNFCEIDDENANGATYVDLTKNPERFTGYMGKSAHRIWNSIYKENCFNEHRN-KYGINLHDAEYLGFLNVIDREQCLEKRIFYRIISGLHTSISIHLCREYLLKDKTGFGSPQWGPNVTEFAKRFDPKFEKD-GPQRLKNLFFTYLVELRAIAKVADYLSEDQFYTGDEVDDKETRLAVKHFLTQVKNFTNHFDEQKLFKGDPKEAKKLKHEFVQHFRNITRIINCVGCDKCKLWGTLQVKGMGTALKILFTNPATPEKTSADKDSFTKISSK-FQLTRTEIVALFNAFGRLSTSVHSLSLFKDL 1470
            ++  F+L  ++    D +S   +A DRCFCKL   VDDCSC V  L+  N  KIYPIL SLL ++YFRYFK+NL + CPFW DDSRCALRDCHV  C   E+P  + + D    +H+++KY    N         C +E    LG LD +IS+ +K     W  YD+    FC+IDDE++N   YVDL  NPER+TGY G S  RIW SIY+ENCF   +N  YG +      +  +  I R  CLEKR+F+R+ISGLHTSI+IHLC +YL   K GFG   W  N+ EF +RFDP    D GPQRLKNL+FTYL+ELRA+AK A YL +  FYTGD  +D++ +  V   L  ++ F +HFDE +LFKG+ KE ++LK EFV HFRNI+RI++CVGCDKCKLWG LQV GMGTALKILF+        S   DS  K   K FQLTRTEIVALFNAFGRLS+S+H++  F+ L
Sbjct:    7 IRLCFVLLFVTSVFSDKLSWSGDAADRCFCKLQGEVDDCSCKVESLDSLNNNKIYPILTSLLSRNYFRYFKVNLKKSCPFWSDDSRCALRDCHVNVCQKDEVPIKIPDVDTHSEKHERNKYLKELNEGKQGFEERCAEERE--LGALDATISEEKKAEFQTWKEYDETLPLFCDIDDEHSNDMEYVDLLLNPERYTGYKGPSPRRIWRSIYEENCFKPEKNYGYGPDYGKDASIESMFFIARGMCLEKRVFFRLISGLHTSINIHLCDKYLFPAKNGFGQSYWDHNLQEFQQRFDPALTHDQGPQRLKNLYFTYLIELRALAKAAPYLKQKGFYTGDNQEDEDVQKGVNDLLDIIRKFPDHFDESQLFKGNTKEMQQLKSEFVLHFRNISRIMDCVGCDKCKLWGKLQVLGMGTALKILFSG------DSMGPDSIVKSQDKDFQLTRTEIVALFNAFGRLSSSIHAIETFRKL 472
[Close]
BLAST of ERO1-like protein beta vs. TrEMBL
Match: K1QN22 (ERO1-like protein beta OS=Crassostrea gigas OX=29159 GN=CGI_10009433 PE=4 SV=1)

HSP 1 Score: 472.241 bits (1214), Expect = 4.212e-158
Identity = 241/464 (51.94%), Postives = 309/464 (66.59%), Query Frame = 1 
Query:   85 YIFLLYILSLTLKDCISNAVDRCFCKLNESVDDCSCPVTDLEDYNT-KIYPILQSLLVKDYFRYFKINLNRECPFWVDDSRCALRDCHVKGCGPKEIPKGLQEDDPVYIEHQKSKYFGTPNIVHHPECLDENHGGLGNLDISISQTQKEVMHNWTIYDDQQDNFCEIDDENANGATYVDLTKNPERFTGYMGKSAHRIWNSIYKENCFNEHRNKYGINLHDAEYLGFLNVIDREQCLEKRIFYRIISGLHTSISIHLCREYLLKDKTGFGSPQWGPNVTEFAKRFDPKFEK-DGPQRLKNLFFTYLVELRAIAKVADYLSEDQFYTGDEVDDKETRLAVKHFLTQVKNFTNHFDEQKLFKGDPKEAKKLKHEFVQHFRNITRIINCVGCDKCKLWGTLQVKGMGTALKILFTNPATPEKTSADKDSFTKISSKFQLTRTEIVALFNAFGRLSTSVHSLSLFKDL 1470
            ++ L   L L  K+   +    CFCKL   VDDCSC V +L+  N  K+YP+L+SLL +DYFRYFK+NL + CPFW DDSRCAL+DCHV+ C   ++P+GL+ +     E + +KY         P C +E    LG LD +IS    E   NWT +DD+Q+ FCEIDDE      YVDL  NPER+TGY G S HRIW SIY+ENCF   +  YG      + L  L       CLE+R FYR++SGLHTSI++HLC EYL   K    +P++GPN  EF +RFDPK  K  GPQRLKNL+FTYLVELRA+ K A YL E+ F+TG+  +DK+ +  VK FL  +K+F +HFDE KLFKGDPK A+KLK EF +HFRNI+RI++CVGCDKCKLWG LQV+GMGTALKILF+     ++   +         +FQL R+EIV+LFNAFGRLS+S+ ++  F+ L
Sbjct:    9 FVLLAISLLLDAKNGSKSQPSACFCKLQGEVDDCSCKVENLDSLNNRKVYPVLKSLLQRDYFRYFKVNLMKPCPFWSDDSRCALKDCHVQSCTEDQVPEGLKGNKN---EREPNKYSKEAQ-KEEPNCNEERE--LGALDRTISAESMEAFKNWTQHDDKQETFCEIDDEYTPDCQYVDLLLNPERYTGYKGASPHRIWKSIYEENCFKPEKLVYG----SKKSLAGL-------CLEQRAFYRLVSGLHTSINLHLCNEYLFPAKNLLSAPEFGPNTEEFIRRFDPKPTKGQGPQRLKNLYFTYLVELRALVKAAPYLEEEDFFTGNPEEDKDVKEGVKDFLEIIKSFPDHFDESKLFKGDPKVAEKLKTEFREHFRNISRIMDCVGCDKCKLWGKLQVQGMGTALKILFSG----DRIGLESTVNAHHKQRFQLRRSEIVSLFNAFGRLSSSIQTIEKFRKL 451
[Close]
BLAST of ERO1-like protein beta vs. TrEMBL
Match: A0A2C9KB90 (Uncharacterized protein OS=Biomphalaria glabrata OX=6526 GN=106055939 PE=4 SV=1)

HSP 1 Score: 471.855 bits (1213), Expect = 1.308e-157
Identity = 248/477 (51.99%), Postives = 312/477 (65.41%), Query Frame = 1 
Query:   79 LKYIFLLYILSLTLKDCIS---NAVDRCFCKLNESVDDCSCPVTDLEDYNT-KIYPILQSLLVKDYFRYFKINLNRECPFWVDDSRCALRDCHVKGCGPKEIPKGLQEDDPVYIEHQKSKYFGTPNIVHH---PECLDENHGGLGNLDISISQTQKEVMHNWTIYDDQQDNFCEIDDENANGATYVDLTKNPERFTGYMGKSAHRIWNSIYKENCFNEHRN-KYGINLHDAEYLGFLNVIDRE---QCLEKRIFYRIISGLHTSISIHLCREYLLKDKTGFGSPQWGPNVTEFAKRFDPKFEKD-GPQRLKNLFFTYLVELRAIAKVADYLSEDQFYTGDEVDDKETRLAVKHFLTQVKNFTNHFDEQKLFKGDPKEAKKLKHEFVQHFRNITRIINCVGCDKCKLWGTLQVKGMGTALKILFTNPATPEKTSADKDSFTKISSK-FQLTRTEIVALFNAFGRLSTSVHSLSLFKDL 1470
            ++  F+L  ++    D +S   +A DRCFCKL   VDDCSC V  L+  N  KIYPIL SLL ++YFRYFK+NL + CPFW DDSRCALRDCHV  C   E+P  + + D    +H+++KY    N         C +E    LG LD +IS+ +K     W  YD+    FC+IDDE++N   YVDL  NPER+TGY G S  RIW SIY+ENCF   +N  YG +      +  +  I RE    CLEKR+F+R+ISGLHTSI+IHLC +YL   K GFG   W  N+ EF +RFDP    D GPQRLKNL+FTYL+ELRA+AK A YL +  FYTGD  +D++ +  V   L  ++ F +HFDE +LFKG+ KE ++LK EFV HFRNI+RI++CVGCDKCKLWG LQV GMGTALKILF+        S   DS  K   K FQLTRTEIVALFNAFGRLS+S+H++  F+ L
Sbjct:    7 IRLCFVLLFVTSVFSDKLSWSGDAADRCFCKLQGEVDDCSCKVESLDSLNNNKIYPILTSLLSRNYFRYFKVNLKKSCPFWSDDSRCALRDCHVNVCQKDEVPIKIPDVDTHSEKHERNKYLKELNEGKQGFEERCAEERE--LGALDATISEEKKAEFQTWKEYDETLPLFCDIDDEHSNDMEYVDLLLNPERYTGYKGPSPRRIWRSIYEENCFKPEKNYGYGPDYGKDASIESMFFIAREIWSMCLEKRVFFRLISGLHTSINIHLCDKYLFPAKNGFGQSYWDHNLQEFQQRFDPALTHDQGPQRLKNLYFTYLIELRALAKAAPYLKQKGFYTGDNQEDEDVQKGVNDLLDIIRKFPDHFDESQLFKGNTKEMQQLKSEFVLHFRNISRIMDCVGCDKCKLWGKLQVLGMGTALKILFSG------DSMGPDSIVKSQDKDFQLTRTEIVALFNAFGRLSSSIHAIETFRKL 475
[Close]
BLAST of ERO1-like protein beta vs. TrEMBL
Match: A0A2C9KB92 (Uncharacterized protein OS=Biomphalaria glabrata OX=6526 GN=106055939 PE=4 SV=1)

HSP 1 Score: 471.085 bits (1211), Expect = 1.888e-157
Identity = 248/473 (52.43%), Postives = 312/473 (65.96%), Query Frame = 1 
Query:   79 LKYIFLLYILSLTLKDCIS---NAVDRCFCKLNESVDDCSCPVTDLEDYNT-KIYPILQSLLVKDYFRYFKINLNRECPFWVDDSRCALRDCHVKGCGPKEIPKGLQEDDPVYIEHQKSKYFGTPNIVHH---PECLDENHGGLGNLDISISQTQKEVMHNWTIYDDQQDNFCEIDDENANGATYVDLTKNPERFTGYMGKSAHRIWNSIYKENCFNEHRNKYGINLHDAEYLGFLNVIDREQCLEKRIFYRIISGLHTSISIHLCREYLLKDKTGFGSPQWGPNVTEFAKRFDPKFEKD-GPQRLKNLFFTYLVELRAIAKVADYLSEDQFYTGDEVDDKETRLAVKHFLTQVKNFTNHFDEQKLFKGDPKEAKKLKHEFVQHFRNITRIINCVGCDKCKLWGTLQVKGMGTALKILFTNPATPEKTSADKDSFTKISSK-FQLTRTEIVALFNAFGRLSTSVHSLSLFKDL 1470
            ++  F+L  ++    D +S   +A DRCFCKL   VDDCSC V  L+  N  KIYPIL SLL ++YFRYFK+NL + CPFW DDSRCALRDCHV  C   E+P  + + D    +H+++KY    N         C +E    LG LD +IS+ +K     W  YD+    FC+IDDE++N   YVDL  NPER+TGY G S  RIW SIY+ENCF   +N YG   +  +Y G    I+   CLEKR+F+R+ISGLHTSI+IHLC +YL   K GFG   W  N+ EF +RFDP    D GPQRLKNL+FTYL+ELRA+AK A YL +  FYTGD  +D++ +  V   L  ++ F +HFDE +LFKG+ KE ++LK EFV HFRNI+RI++CVGCDKCKLWG LQV GMGTALKILF+        S   DS  K   K FQLTRTEIVALFNAFGRLS+S+H++  F+ L
Sbjct:    7 IRLCFVLLFVTSVFSDKLSWSGDAADRCFCKLQGEVDDCSCKVESLDSLNNNKIYPILTSLLSRNYFRYFKVNLKKSCPFWSDDSRCALRDCHVNVCQKDEVPIKIPDVDTHSEKHERNKYLKELNEGKQGFEERCAEERE--LGALDATISEEKKAEFQTWKEYDETLPLFCDIDDEHSNDMEYVDLLLNPERYTGYKGPSPRRIWRSIYEENCFKPEKN-YG---YGPDY-GKDASIESSMCLEKRVFFRLISGLHTSINIHLCDKYLFPAKNGFGQSYWDHNLQEFQQRFDPALTHDQGPQRLKNLYFTYLIELRALAKAAPYLKQKGFYTGDNQEDEDVQKGVNDLLDIIRKFPDHFDESQLFKGNTKEMQQLKSEFVLHFRNISRIMDCVGCDKCKLWGKLQVLGMGTALKILFSG------DSMGPDSIVKSQDKDFQLTRTEIVALFNAFGRLSSSIHAIETFRKL 466
[Close]
BLAST of ERO1-like protein beta vs. TrEMBL
Match: A0A3G4RIH8 (Endoplasmic reticulum oxidoreductin isoform X2 (Fragment) OS=Conus geographus OX=6491 GN=Ero1 PE=2 SV=1)

HSP 1 Score: 470.315 bits (1209), Expect = 2.558e-157
Identity = 243/452 (53.76%), Postives = 304/452 (67.26%), Query Frame = 1 
Query:  136 NAVDRCFCKLNESVDDCSCPVTDLEDYNT-KIYPILQSLLVKDYFRYFKINLNRECPFWVDDSRCALRDCHVKGCGPKEIPKGLQEDDPVYIEHQKSKYFGTPNIVHHPECLDENHGGLGNLDISISQTQKEVMHNWTIYDDQQDNFCEIDDENANGATYVDLTKNPERFTGYMGKSAHRIWNSIYKENCFNEHRN-KYGINLHDAEYLGFLNVIDREQCLEKRIFYRIISGLHTSISIHLCREYLLKDKTGFGSPQWGPNVTEFAKRFDP-KFEKDGPQRLKNLFFTYLVELRAIAKVADYLSEDQFYTGDEVDDKETRLAVKHFLTQVKNFTNHFDEQKLFKGDPKEAKKLKHEFVQHFRNITRIINCVGCDKCKLWGTLQVKGMGTALKILFTNPAT-PEKT-SADKDSFTKISSKFQLTRTEIVALFNAFGRLSTSVHSLSLFKDLMK 1476
            N    CFCKL   VDDCSC V  L+  N  KIYP L SL+ K+YFRYFK+NL ++CPFW DDSRCAL+DCHVK C    +P     D+ +  +  ++KY        H  C +E    L  LD ++S   K+   +W+ YDD  D FCEIDDE++    YVDL KNPER+TGY G S HRIW S+Y+ENCF       YG      + L       +  CLEKR FYR+ISGLHTSI+IHLC +YL    T F SP+WGPNV EF KRFDP   E  GPQRLKNL+FTYLVELRA+AK A Y+ +++FYTG+  +D E R AVK F++ V++F +HFDE+KLF+G+  E +KLK EF  HFRNI+RI++CVGCDKCKLWG LQV GMGTALKILF+  +  PE T SAD        + FQL+RTEIVA FNAF RLS+S+H++  F+ L++
Sbjct:   25 NVSQGCFCKLKGEVDDCSCKVESLDSLNNDKIYPRLSSLMRKNYFRYFKVNLQKQCPFWTDDSRCALKDCHVKICEQDTVPIV---DEKLNKQDTENKYSKEAQQADH-SCEEERQ--LSALDTTLSDENKQAFQDWSDYDDSLDMFCEIDDEHSAELQYVDLLKNPERYTGYKGASPHRIWRSVYEENCFKPSEPVTYGPK---EDNLSITEDWLQGMCLEKRAFYRMISGLHTSINIHLCDQYLQPAPTAFASPKWGPNVKEFRKRFDPDTTEGQGPQRLKNLYFTYLVELRAMAKAAPYILQEEFYTGNAEEDAEVRTAVKDFISVVRDFPDHFDERKLFQGNSAETQKLKREFRDHFRNISRIMDCVGCDKCKLWGKLQVLGMGTALKILFSGSSMGPESTVSAD------FKADFQLSRTEIVAFFNAFSRLSSSIHAVETFRALLR 461
[Close]
BLAST of ERO1-like protein beta vs. Ensembl Cavefish
Match: ero1b (endoplasmic reticulum oxidoreductase 1 beta [Source:NCBI gene;Acc:103042263])

HSP 1 Score: 404.06 bits (1037), Expect = 1.927e-134
Identity = 212/456 (46.49%), Postives = 287/456 (62.94%), Query Frame = 1 
Query:  151 CFCKLNESVDDCSCPVTDLEDYNT-KIYPILQSLLVKDYFRYFKINLNRECPFWVDDSRCALRDCHVKGCGPKEIPKGLQEDDPVYIEHQKSKYFGTPNIVH-HPECLDENHGGLGNLDISISQTQKEVMHNWTIYDDQQDNFCEIDDENANGATYVDLTKNPERFTGYMGKSAHRIWNSIYKENCFNEHR-----NKYGINLHDAEYLGFLNVIDREQCLEKRIFYRIISGLHTSISIHLCREYLLKDKTGFGSPQWGPNVTEFAKRFD-PKFEKDGPQRLKNLFFTYLVELRAIAKVADYLSED--QFYTGDEVDDKETRLAVKHFLTQVKNFTNHFDEQKLFKGDPKEAKKLKHEFVQHFRNITRIINCVGCDKCKLWGTLQVKGMGTALKILFTNPAT---PEKTSADKDSFTKISSKFQLTRTEIVALFNAFGRLSTSVHSLSLFKDLMKD 1479
            C C L   +DDC C +  ++ +N  KI+P++Q L+ +D+FRY+++NL R CPFW DDS CA++DCHV+ C   +IP G++  +        +KY    N +    EC   N   LG ++ ++S   KE   +W  +DD QD+FC +DDE +  A YVDL  NPER+TGY G SA R+WNSIY+ENCF         N       D +  GF N ++   CLEKR+FY++ISGLH+SI+IHLC EYLL ++  +G P WGPNV EF +RFD  + +++G +RLKNL+F YL+ELRA++KVA Y        YTG+  +D  T+  +   L + K F  HFDE  +F G   EAK+LK EF  HF+NI+RI++CVGC KC+LWG LQ +G+GTAL ILF+       PE +          S  FQLTR EIVAL NAFGRLSTS+  L  F+ L+KD
Sbjct:   54 CLCHLTGVLDDCFCDIESIDVFNNFKIFPLIQKLIERDFFRYYRVNLMRPCPFWPDDSHCAIKDCHVEPCPESKIPVGIKSGN-------YNKYSHAANTIRDMKECEQANE--LGAINSTLSNQSKEAFMDWAHHDDAQDHFCGLDDETSPDAEYVDLRLNPERYTGYKGPSAWRVWNSIYEENCFKPRSVYRPLNPLAPTRGDDDGEGFYNWLE-GLCLEKRVFYKLISGLHSSINIHLCAEYLLDER--WGKPTWGPNVHEFRRRFDSAETKEEGTRRLKNLYFLYLIELRALSKVAPYFERAFINLYTGNSQEDSVTKELLLQILNETKAFPMHFDESSMFAGHKMEAKRLKEEFRLHFKNISRIMDCVGCSKCRLWGKLQTQGLGTALMILFSEKEIKNLPENSP---------SKGFQLTRQEIVALLNAFGRLSTSIKELHNFRTLLKD 488
[Close]
BLAST of ERO1-like protein beta vs. Ensembl Cavefish
Match: ero1b (endoplasmic reticulum oxidoreductase 1 beta [Source:NCBI gene;Acc:103042263])

HSP 1 Score: 397.127 bits (1019), Expect = 4.530e-132
Identity = 210/452 (46.46%), Postives = 285/452 (63.05%), Query Frame = 1 
Query:  163 LNESVDDCSCPVTDLEDYNT-KIYPILQSLLVKDYFRYFKINLNRECPFWVDDSRCALRDCHVKGCGPKEIPKGLQEDDPVYIEHQKSKYFGTPNIVH-HPECLDENHGGLGNLDISISQTQKEVMHNWTIYDDQQDNFCEIDDENANGATYVDLTKNPERFTGYMGKSAHRIWNSIYKENCFNEHR-----NKYGINLHDAEYLGFLNVIDREQCLEKRIFYRIISGLHTSISIHLCREYLLKDKTGFGSPQWGPNVTEFAKRFD-PKFEKDGPQRLKNLFFTYLVELRAIAKVADYLSED--QFYTGDEVDDKETRLAVKHFLTQVKNFTNHFDEQKLFKGDPKEAKKLKHEFVQHFRNITRIINCVGCDKCKLWGTLQVKGMGTALKILFTNPAT---PEKTSADKDSFTKISSKFQLTRTEIVALFNAFGRLSTSVHSLSLFKDLMKD 1479
            L   +DDC C +  ++ +N  KI+P++Q L+ +D+FRY+++NL R CPFW DDS CA++DCHV+ C   +IP G++  +        +KY    N +    EC   N   LG ++ ++S   KE   +W  +DD QD+FC +DDE +  A YVDL  NPER+TGY G SA R+WNSIY+ENCF         N       D +  GF N ++   CLEKR+FY++ISGLH+SI+IHLC EYLL ++  +G P WGPNV EF +RFD  + +++G +RLKNL+F YL+ELRA++KVA Y        YTG+  +D  T+  +   L + K F  HFDE  +F G   EAK+LK EF  HF+NI+RI++CVGC KC+LWG LQ +G+GTAL ILF+       PE +          S  FQLTR EIVAL NAFGRLSTS+  L  F+ L+KD
Sbjct:   31 LTGVLDDCFCDIESIDVFNNFKIFPLIQKLIERDFFRYYRVNLMRPCPFWPDDSHCAIKDCHVEPCPESKIPVGIKSGN-------YNKYSHAANTIRDMKECEQANE--LGAINSTLSNQSKEAFMDWAHHDDAQDHFCGLDDETSPDAEYVDLRLNPERYTGYKGPSAWRVWNSIYEENCFKPRSVYRPLNPLAPTRGDDDGEGFYNWLE-GLCLEKRVFYKLISGLHSSINIHLCAEYLLDER--WGKPTWGPNVHEFRRRFDSAETKEEGTRRLKNLYFLYLIELRALSKVAPYFERAFINLYTGNSQEDSVTKELLLQILNETKAFPMHFDESSMFAGHKMEAKRLKEEFRLHFKNISRIMDCVGCSKCRLWGKLQTQGLGTALMILFSEKEIKNLPENSP---------SKGFQLTRQEIVALLNAFGRLSTSIKELHNFRTLLKD 461
[Close]
BLAST of ERO1-like protein beta vs. Ensembl Cavefish
Match: ero1a (endoplasmic reticulum oxidoreductase 1 alpha [Source:NCBI gene;Acc:103038336])

HSP 1 Score: 383.259 bits (983), Expect = 9.691e-127
Identity = 206/471 (43.74%), Postives = 288/471 (61.15%), Query Frame = 1 
Query:  100 YILSLTLKDCISNAVDRCFCKLNESVDDCSCPVTDLEDYNT-KIYPILQSLLVKDYFRYFKINLNRECPFWVDDSRCALRDCHVKGCGPKEIPKGLQEDDPVYIEHQKSKYFGTPNIVHHPECLDENHGGLGNLDISISQTQKEVMHNWTIYDDQQDNFCEIDDENANGATYVDLTKNPERFTGYMGKSAHRIWNSIYKENCFNEHRNKYGIN-----LHDAEYLGFLNVIDREQCLEKRIFYRIISGLHTSISIHLCREYLLKDKTGFGSPQWGPNVTEFAKRFDPKFEK-DGPQRLKNLFFTYLVELRAIAKVADYLSEDQF--YTGDEVDDKETRLAVKHFLTQVKNFTNHFDEQKLFKGDPKEAKKLKHEFVQHFRNITRIINCVGCDKCKLWGTLQVKGMGTALKILFTNPA--TPEKTSADKDSFTKISSKFQLTRTEIVALFNAFGRLSTSVHSLSLFKDLMKD 1479
            + L   L   I  ++  CFC +  S+DDC+C V  ++ +N  K++  LQ+LL  DYFR++K+NLN  CPFW D   C LRDC VK C   E+P+GL+      +E  +          H  EC  E    LG ++ S+S   ++ +  W  +DD+ D FC  DDE++  A YVDL  NPER+TGY G  A +IWNSIY+ENCF  +  K  +N       D E  GF + ++ + C+EKR F+R++SGLH SI++HL   YLL D   +   +WG NV+EF  RFD    K +GP+RL+NL+F YL+ELRA+AKV  +  +  F  YTG    D+  +  +   L   ++F  HFDE  LF GD KEA +LK++F Q FRNI+RI++CVGC KC+LWG LQ +G+GTALKILF+     T  ++S+ + S       FQL+R EIV+LFNAFGR+STS+  L  F+ L+ +
Sbjct:    4 FALLSVLFTLIPGSLAACFCTVTGSLDDCACDVETIDTFNNQKLFSKLQNLLSSDYFRFYKVNLNNPCPFWTDSGHCGLRDCAVKPCTASEVPEGLKSSYKYSLEASE----------HTEEC--EMAEKLGAVNGSLSDETRQALLEWNRHDDEADRFCMHDDEDSPQAQYVDLLLNPERYTGYKGPEAWQIWNSIYEENCFKPYTVKRPLNPLVSSAGDGEGRGFYSWLE-DLCVEKRAFFRLVSGLHASINVHLSARYLLDD--NWFERKWGHNVSEFKLRFDDDLTKGEGPKRLRNLYFLYLIELRALAKVQPFFQQPSFSLYTGQPEQDRANKHLLLELLHLARSFPLHFDETTLFAGDKKEAAQLKNDFRQTFRNISRIMDCVGCFKCRLWGKLQTQGLGTALKILFSEKQIETLPQSSSSRPS-------FQLSRQEIVSLFNAFGRVSTSIRELENFRKLLSE 452
[Close]
BLAST of ERO1-like protein beta vs. Ensembl Cavefish
Match: ero1b (endoplasmic reticulum oxidoreductase 1 beta [Source:NCBI gene;Acc:103042263])

HSP 1 Score: 378.637 bits (971), Expect = 1.041e-124
Identity = 206/455 (45.27%), Postives = 278/455 (61.10%), Query Frame = 1 
Query:  151 CFCKLNESVDDCSCPVTDLEDYNT-KIYPILQSLLVKDYFRYFKINLNRECPFWVDDSRCALRDCHVKGCGPKEIPKGLQEDDPVYIEHQKSKYFGTPNIVHHPECLDENHGGLGNLDISISQTQKEVMHNWTIYDDQQDNFCEIDDENANGATYVDLTKNPERFTGYMGKSAHRIWNSIYKENCFNEHR-----NKYGINLHDAEYLGFLNVIDREQCLEKRIFYRIISGLHTSISIHLCREYLLKDKTGFGSPQWGPNVTEFAKRFD-PKFEKDGPQRLKNLFFTYLVELRAIAKVADYLSED--QFYTGDEVDDKETRLAVKHFLTQVKNFTNHFDEQKLFKGDPKEAKKLKHEFVQHFRNITRIINCVGCDKCKLWGTLQVKGMGTALKILFTNPAT---PEKTSADKDSFTKISSKFQLTRTEIVALFNAFGRLSTSVHSLSLFKDLMKD 1479
            C C L   +DDC C +  ++ +N  KI+P++Q L+ +D+FRY+++NL R CPFW DDS CA++DCHV+ C P+     L      YI+          NI      ++ + G L   + S     KE   +W  +DD QD+FC +DDE +  A YVDL  NPER+TGY G SA R+WNSIY+ENCF         N       +  +  F+  +    CLEKR+FY++ISGLH+SI+IHLC EYLL ++  +G P WGPNV EF +RFD  + +++G +RLKNL+F YL+ELRA++KVA Y        YTG+  +D  T+  +   L + K F  HFDE  +F G   EAK+LK EF  HF+NI+RI++CVGC KC+LWG LQ +G+GTAL ILF+       PE +          S  FQLTR EIVAL NAFGRLSTS+  L  F+ L+KD
Sbjct:   54 CLCHLTGVLDDCFCDIESIDVFNNFKIFPLIQKLIERDFFRYYRVNLMRPCPFWPDDSHCAIKDCHVEPC-PEVSAHHLLSLISTYIQ----------NIPFSFSYVNRSGGCLLYYNQS-----KEAFMDWAHHDDAQDHFCGLDDETSPDAEYVDLRLNPERYTGYKGPSAWRVWNSIYEENCFKPRSVYRPLNPLAPTRGEFNFFFFMFYVHIWLCLEKRVFYKLISGLHSSINIHLCAEYLLDER--WGKPTWGPNVHEFRRRFDSAETKEEGTRRLKNLYFLYLIELRALSKVAPYFERAFINLYTGNSQEDSVTKELLLQILNETKAFPMHFDESSMFAGHKMEAKRLKEEFRLHFKNISRIMDCVGCSKCRLWGKLQTQGLGTALMILFSEKEIKNLPENSP---------SKGFQLTRQEIVALLNAFGRLSTSIKELHNFRTLLKD 481
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BLAST of ERO1-like protein beta vs. Ensembl Sea Lamprey
Match: ero1b (endoplasmic reticulum oxidoreductase beta [Source:ZFIN;Acc:ZDB-GENE-060929-744])

HSP 1 Score: 170.244 bits (430), Expect = 8.748e-50
Identity = 88/183 (48.09%), Postives = 116/183 (63.39%), Query Frame = 1 
Query:  163 LNESVDDCSCPVTDLEDYNT-KIYPILQSLLVKDYFRYFKINLNRECPFWVDDSRCALRDCHVKGCGPKEIPKGLQ--EDDPVYIEHQKSKYFGTPNIVHHPECLDENHGGLGNLDISISQTQKEVMHNWTIYDDQQDNFCEIDDENANGATYVDLTKNPERFTGYMGKSAHRIWNSIYKENC 702
            L+  +DDCSC V  ++++N  K++P L +LL KDYFRY+++NL R CPFW DDS C+++DCHVK C P E+P G++  E +    E Q  +Y    N+    +   E    LG +D +IS   K    +W  YDD  DNFCEIDDE +    YVDL  NPER+TGY G SA RIWN IY+ENC
Sbjct:    1 LSGVLDDCSCDVESIDEFNNYKLFPKLWNLLEKDYFRYYRVNLKRPCPFWHDDSHCSIQDCHVKSCKPSEVPSGIKGGEHNKFSFE-QVFQYLEDINVWAKEQQECEEARKLGAIDNTISDQSKVAFIDWARYDDSLDNFCEIDDETSPDMEYVDLRLNPERYTGYKGPSAWRIWNCIYEENC 182
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BLAST of ERO1-like protein beta vs. Ensembl Yeast
Match: ERO1 (Thiol oxidase required for oxidative protein folding in the ER; essential for maintaining ER redox balance; feedback regulated via reduction and oxidation of regulatory bonds; reduced Pdi1p activates Ero1p by direct reduction of Ero1p regulatory bonds; depletion of thiol substrates and accumulation of oxidized Pdi1p results in inactivation of Ero1p by both Pdi1p-mediated oxidation and autonomous oxidation of Ero1p regulatory bonds; ero1-1 mutation complemented by human ERO1L [Source:SGD;Acc:S000004599])

HSP 1 Score: 219.55 bits (558), Expect = 6.618e-64
Identity = 151/446 (33.86%), Postives = 228/446 (51.12%), Query Frame = 1 
Query:  145 DRCFCKL--NESVD-DCSCPVTDLEDYNTKIYPILQSLLVKDYFRYFKINLNRECPFW-VDDSRCALRDCHVKGCGPKEIPKGLQEDDPVYIEHQKSKYFGTPNIVHHPECLDENHGGLGNLDISISQTQKEVMHNWTIYDDQQDNFCEIDDENANGATYVDLTKNPERFTGYMGKSAHRIWNSIYKENCFNEHRNKYGINLHDAEYLGFLNVIDREQCLEKRIFYRIISGLHTSISIHLCREYLLKDKTGFGSPQWGPNVTEFAKRFDPKFEKDGPQRLKNLFFTYLVELRAIAKVADYLSEDQFYTGDEVDDKETRLAVKHFLTQVKNFTNHFDEQKLFKGDPKEAKKLKHEFVQHFRNITRIINCVGCDKCKLWGTLQVKGMGTALKILFTNPATPEKTSADKDSFTKISSKFQLTRTEIVALFNAFGRLSTSVHSLSLFKDL 1470
            D  FCK+  N+ V   C+    +L   N  I   L +LL  D+F+YF+++L ++C FW  +D  C  R C V           + ED     E+ + +  G+ N     E  D++      LD     ++K V    TI      N+C+++D N   A  +DLT NPERFTGY GK A +IW++IY++NCF                     + +  + L K  FYR++SG H SI  HL +EY L  KTG    +W PN+  F  R       + P R+ N++F Y V  +A+ K+  YL E  F    ++ +KE +  + + ++Q+   T  F+E  +F  D   +  LK EF   F+N+T+I++CV CD+C+LWG +Q  G  TALKILF           D D FTK     +LT+ E++AL   FGRLS S+ S+++F+ +
Sbjct:   36 DTHFCKVDRNDHVSPSCNVTFNELNAINENIRDDLSALLKSDFFKYFRLDLYKQCSFWDANDGLCLNRACSV----------DVVEDWDTLPEYWQPEILGSFNNDTMKEA-DDSDDECKFLDQLCQTSKKPVDIEDTI------NYCDVNDFNGKNAVLIDLTANPERFTGYGGKQAGQIWSTIYQDNCF--------------------TIGETGESLAKDAFYRLVSGFHASIGTHLSKEY-LNTKTG----KWEPNLDLFMARIG-----NFPDRVTNMYFNYAVVAKALWKIQPYLPEFSFC---DLVNKEIKNKMDNVISQLD--TKIFNEDLVFANDL--SLTLKDEFRSRFKNVTKIMDCVQCDRCRLWGKIQTTGYATALKILF--------EINDADEFTKQHIVGKLTKYELIALLQTFGRLSESIESVNMFEKM 419
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BLAST of ERO1-like protein beta vs. Ensembl Nematostella
Match: EDO48522 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RJ61])

HSP 1 Score: 349.362 bits (895), Expect = 1.127e-114
Identity = 188/428 (43.93%), Postives = 256/428 (59.81%), Query Frame = 1 
Query:  160 KLNESVDDCSCPVTDLEDYNTKIYPILQSLLVKDYFRYFKINLNRECPFWVDDSRCALRDCHVKGCGPKEIPKGLQEDDPVYIEHQKSKYFGTPNIVHHPECLDENHGGLGNLDISISQTQKEVMHNWTIYDDQQDNFCEIDDENANGATYVDLTKNPERFTGYMGKSAHRIWNSIYKENCFNEH-RNKYGINLHDAEYLGFLNVIDREQCLEKRIFYRIISGLHTSISIHLCREYLLKDKTGFGSPQWGPNVTEFAKRFDP-KFEKDGPQRLKNLFFTYLVELRAIAKVADYLSEDQFYTGDEVDDKETRLAVKHFLTQVKNFTNHFDEQKLFKGDPKEAKKLKHEFVQHFRNITRIINCVGCDKCKLWGTLQVKGMGTALKILFTNPATPEKTSADKDSFTKISSKFQLTRTEIVALFNAFGRLST 1437
            +L   V+ C C V  ++  N KI+PIL  L+ ++YF++F++ L+R CPFW ++  CA+R C V  C  +E+P G++ +   YI  + +  F      +   C + ++  LGNLD +IS   K     W  +D+ ++NFC +DDE+  G  Y+DL +NPE++TGY G SAHRIWNSIY+ENCF        G N   ++ +G L       CLEKR+FYR ISGLH SI+IHL   YL  + T F  P+WG N+ EF  RFD       GP+ LKNL+FTY + LRAI K A Y    +FYTG+  +D+  R  V   L + K   + FDE  LFK DP  A  LK EF  HF N++RI++CVGC+KCK+WG LQV+G+GTALKILF+           K         F LTR+EIV+LFN F R +T
Sbjct:    1 QLKGKVEQCCCDVETVDKINNKIHPILDELVKRNYFKFFRVKLDRPCPFWTNNDVCAIRHCSVLPCKEEEVPVGIKAETSNYIMIEITFTFKGK---YGETCQESSNTTLGNLDDTISAKDKLAFDTWRQHDNVEENFCALDDESTTGLQYIDLLRNPEQYTGYKGFSAHRIWNSIYQENCFKPKIPYSKGYNYLLSKNIGDL-------CLEKRVFYRAISGLHASINIHLSARYLFSE-TAFQKPKWGMNLKEFRSRFDSDATAGQGPEWLKNLYFTYTLVLRAITKAAPYWETMEFYTGEYEEDEYVRKLVFDLLAESKACPSTFDETVLFK-DPATATVLKEEFRSHFHNVSRIMDCVGCEKCKVWGKLQVQGLGTALKILFSGHEFENMNFGGK--------AFYLTRSEIVSLFNGFTRYTT 408
[Close]
BLAST of ERO1-like protein beta vs. Ensembl Medaka
Match: ero1b (endoplasmic reticulum oxidoreductase 1 beta [Source:NCBI gene;Acc:101172050])

HSP 1 Score: 397.897 bits (1021), Expect = 5.119e-132
Identity = 212/456 (46.49%), Postives = 286/456 (62.72%), Query Frame = 1 
Query:  151 CFCKLNESVDDCSCPVTDLEDYNT-KIYPILQSLLVKDYFRYFKINLNRECPFWVDDSRCALRDCHVKGCGPKEIPKGLQEDDPVYIEHQKSKYFGTPN-IVHHPECLDENHGGLGNLDISISQTQKEVMHNWTIYDDQQDNFCEIDDENANGATYVDLTKNPERFTGYMGKSAHRIWNSIYKENCFNEHR-----NKYGINLHDAEYLGFLNVIDREQCLEKRIFYRIISGLHTSISIHLCREYLLKDKTGFGSPQWGPNVTEFAKRFDPKFEK-DGPQRLKNLFFTYLVELRAIAKVADYLSED--QFYTGDEVDDKETRLAVKHFLTQVKNFTNHFDEQKLFKGDPKEAKKLKHEFVQHFRNITRIINCVGCDKCKLWGTLQVKGMGTALKILFTNPAT---PEKTSADKDSFTKISSKFQLTRTEIVALFNAFGRLSTSVHSLSLFKDLMKD 1479
            C C L   +DDC C V  ++ +N  KIYP ++ L  +DYFRY+++NL R CPFW DD  C+++DC V+ C   ++P G++  +        +KY   P+ +V   EC  E    LG ++ ++S   KE   +WT +DD QD+FCE+DDE +  A YVDL  NPER+TGY G SA R+WNSIY+ENCF         N    +  D +  GF + ++   CLEKR+FYR+ISGLH+SI+IHLC EYLL +  G+G   WGPN+ EF  RFD    K +G +RLKNL+F YL+ELRA+ KVA Y        YTG+  +D ET+  +     ++K F  HFDE+ +F G+  EAK LK EF  HF+NI+RI++CVGC KC+LWG LQ +G+GTALKILF+       PE +          S  FQLTR EIVAL NAF RLSTS+H L  F+ ++K+
Sbjct:   51 CLCHLTGVLDDCFCDVESIDVFNNFKIYPQIKKLTERDYFRYYRVNLKRPCPFWPDDGHCSIKDCQVEPCPESKVPDGIKSGN-------YNKYSQAPSTMVDMQEC--EQAKELGAINSTLSNQSKEAFADWTRHDDAQDHFCELDDETSPDAEYVDLLLNPERYTGYKGPSAWRVWNSIYEENCFKPRSVYRPLNPLAPSRGDDDGEGFYDWLE-GLCLEKRVFYRLISGLHSSINIHLCAEYLLDE--GWGRAVWGPNIQEFRLRFDTAETKGEGTRRLKNLYFLYLIELRALYKVAPYFERAIVNLYTGNAEEDGETKELLLSIFNKIKTFPMHFDEKSMFAGNKIEAKTLKEEFRLHFKNISRIMDCVGCSKCRLWGKLQTQGLGTALKILFSEKEIQNLPEHSP---------SKGFQLTRHEIVALINAFARLSTSIHQLHNFRLMLKE 485
[Close]
BLAST of ERO1-like protein beta vs. Ensembl Medaka
Match: ero1b (endoplasmic reticulum oxidoreductase 1 beta [Source:NCBI gene;Acc:101172050])

HSP 1 Score: 382.489 bits (981), Expect = 1.515e-126
Identity = 208/460 (45.22%), Postives = 276/460 (60.00%), Query Frame = 1 
Query:  151 CFCKLNESVDDCSCPVTDLEDYNT-KIYPILQSLLVKDYFRYFKINLNRECPFWVDDSRCALRDCHVKGCGPKEIPKGLQEDDPVYIEHQKSKYFGTPNIVHH--PECLD-------ENHGGLGNLDISISQTQKEVMHNWTIYDDQQDNFCEIDDENANGATYVDLTKNPERFTGYMGKSAHRIWNSIYKENCFNEHRNKYGIN-LHDAEYLGFLNVIDREQCLEKRIFYRIISGLHTSISIHLCREYLLKDKTGFGSPQWGPNVTEFAKRFDPKFEK-DGPQRLKNLFFTYLVELRAIAKVADYLSED--QFYTGDEVDDKETRLAVKHFLTQVKNFTNHFDEQKLFKGDPKEAKKLKHEFVQHFRNITRIINCVGCDKCKLWGTLQVKGMGTALKILFTNPAT---PEKTSADKDSFTKISSKFQLTRTEIVALFNAFGRLSTSVHSLSLFKDLMKD 1479
            C  +L   +DDC C V  ++ +N  KIYP ++ L  +DYFRY+++NL R CPFW DD  C+++DC V+ C                           P +  H  P CL        E    LG ++ ++S   KE   +WT +DD QD+FCE+DDE +  A YVDL  NPER+TGY G SA R+WNSIY+ENCF        +N L  +   GF + ++   CLEKR+FYR+ISGLH+SI+IHLC EYLL +  G+G   WGPN+ EF  RFD    K +G +RLKNL+F YL+ELRA+ KVA Y        YTG+  +D ET+  +     ++K F  HFDE+ +F G+  EAK LK EF  HF+NI+RI++CVGC KC+LWG LQ +G+GTALKILF+       PE +          S  FQLTR EIVAL NAF RLSTS+H L  F+ ++K+
Sbjct:   29 CLLQLTGVLDDCFCDVESIDVFNNFKIYPQIKKLTERDYFRYYRVNLKRPCPFWPDDGHCSIKDCQVEPC---------------------------PEVRGHSLPHCLSFSSTSECEQAKELGAINSTLSNQSKEAFADWTRHDDAQDHFCELDDETSPDAEYVDLLLNPERYTGYKGPSAWRVWNSIYEENCFKPRSVYRPLNPLAPSRGEGFYDWLE-GLCLEKRVFYRLISGLHSSINIHLCAEYLLDE--GWGRAVWGPNIQEFRLRFDTAETKGEGTRRLKNLYFLYLIELRALYKVAPYFERAIVNLYTGNAEEDGETKELLLSIFNKIKTFPMHFDEKSMFAGNKIEAKTLKEEFRLHFKNISRIMDCVGCSKCRLWGKLQTQGLGTALKILFSEKEIQNLPEHSP---------SKGFQLTRHEIVALINAFARLSTSIHQLHNFRLMLKE 449
[Close]
BLAST of ERO1-like protein beta vs. Ensembl Medaka
Match: ero1a (ERO1-like protein alpha [Source:NCBI gene;Acc:101167922])

HSP 1 Score: 376.711 bits (966), Expect = 2.225e-124
Identity = 202/461 (43.82%), Postives = 280/461 (60.74%), Query Frame = 1 
Query:  148 RCFCKLNESVDDCSCPVTDLEDYNT-KIYPILQSLLVKDYFRYFKINLNRECPFWVDDSRCALRDCHVKGCGPKEIPKGLQEDDPVYIEHQKSKYFGTPNIVHHPECLDENHGGLGNLDISISQTQKEVMHNWTIYDDQQDNFCEIDDENANGATYVDLTKNPERFTGYMGKSAHRIWNSIYKENCFNEHRNKYGINLHDAEYLGFLNVIDRE----------QCLEKRIFYRIISGLHTSISIHLCREYLLKDKTGFGSPQWGPNVTEFAKRFDPKFEK-DGPQRLKNLFFTYLVELRAIAKVADYLSED--QFYTGDEVDDKETRLAVKHFLTQVKNFTNHFDEQKLFKGDPKEAKKLKHEFVQHFRNITRIINCVGCDKCKLWGTLQVKGMGTALKILFTN---PATPEKTSADKDSFTKISSKFQLTRTEIVALFNAFGRLSTSVHSLSLFKDLMKD 1479
            RCFC++   +DDC+C V  ++D+N  +++P LQ+LL  DYFR++K+NL + CPFW   S C LRDC VK C P ++P+G++           +KY   PN     EC    H  LG +D+S+S+  +E + +W+ +DD+ + FC +DDE      +VDL  NPERFTGY G  A +IWNSIY+ENCF     K  + L D+    FL+    E          QC+EKR FYR+ISGLH SI+IHL   YLL D   +   +WG N +EF +RFD +    +GP+RL NL+F YL+ELRA+AK   +  +   Q YTG   +D++ +  +   L   ++F  HFDE  LF GD KEA KLK +    F NI+RI++CVGC KC+LWG LQ +G+GTALKILF+     A P+             S+FQL+R E+V+L NAFGR+STSV  L  F+ L+ +
Sbjct:   19 RCFCQVTGHLDDCACDVETIDDFNNNQLFPKLQTLLESDYFRFYKVNLQKPCPFWTSTSHCGLRDCAVKPCSPSDVPEGIRSSP-------HNKYLKEPN-QQLDECERAEH--LGAVDVSLSEKTREALQDWSRHDDEAERFCVVDDEEPPDWQHVDLLLNPERFTGYSGPDAWQIWNSIYEENCFKPLTIKRPL-LPDS----FLSSSGNEARTFHRWLKGQCVEKRAFYRLISGLHASINIHLSARYLLDD--SWYQKKWGHNASEFRRRFDSELTAGEGPRRLLNLYFLYLIELRALAKALPFFQQPSFQLYTGRAEEDQKHKELLLQILQAARSFPLHFDETTLFAGDEKEAAKLKEDIRLAFVNISRIMDCVGCFKCRLWGKLQTQGLGTALKILFSGRQIEALPK-------------SRFQLSRQEVVSLLNAFGRISTSVRELQNFRSLLSE 449
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BLAST of ERO1-like protein beta vs. Ensembl Medaka
Match: ero1b (endoplasmic reticulum oxidoreductase 1 beta [Source:NCBI gene;Acc:101172050])

HSP 1 Score: 358.607 bits (919), Expect = 2.466e-117
Identity = 193/412 (46.84%), Postives = 258/412 (62.62%), Query Frame = 1 
Query:  280 INLNRECPFWVDDSRCALRDCHVKGCGPKEIPKGLQEDDPVYIEHQKSKYFGTPN-IVHHPECLDENHGGLGNLDISISQTQKEVMHNWTIYDDQQDNFCEIDDENANGATYVDLTKNPERFTGYMGKSAHRIWNSIYKENCFNEHR-----NKYGINLHDAEYLGFLNVIDREQCLEKRIFYRIISGLHTSISIHLCREYLLKDKTGFGSPQWGPNVTEFAKRFDPKFEK-DGPQRLKNLFFTYLVELRAIAKVADYLSED--QFYTGDEVDDKETRLAVKHFLTQVKNFTNHFDEQKLFKGDPKEAKKLKHEFVQHFRNITRIINCVGCDKCKLWGTLQVKGMGTALKILFTNPAT---PEKTSADKDSFTKISSKFQLTRTEIVALFNAFGRLSTSVHSLSLFKDLMKD 1479
            +NL R CPFW DD  C+++DC V+ C   ++P G++  +        +KY   P+ +V   EC  E    LG ++ ++S   KE   +WT +DD QD+FCE+DDE +  A YVDL  NPER+TGY G SA R+WNSIY+ENCF         N    +  D +  GF + ++   CLEKR+FYR+ISGLH+SI+IHLC EYLL +  G+G   WGPN+ EF  RFD    K +G +RLKNL+F YL+ELRA+ KVA Y        YTG+  +D ET+  +     ++K F  HFDE+ +F G+  EAK LK EF  HF+NI+RI++CVGC KC+LWG LQ +G+GTALKILF+       PE +          S  FQLTR EIVAL NAF RLSTS+H L  F+ ++K+
Sbjct:   55 VNLKRPCPFWPDDGHCSIKDCQVEPCPESKVPDGIKSGN-------YNKYSQAPSTMVDMQEC--EQAKELGAINSTLSNQSKEAFADWTRHDDAQDHFCELDDETSPDAEYVDLLLNPERYTGYKGPSAWRVWNSIYEENCFKPRSVYRPLNPLAPSRGDDDGEGFYDWLE-GLCLEKRVFYRLISGLHSSINIHLCAEYLLDE--GWGRAVWGPNIQEFRLRFDTAETKGEGTRRLKNLYFLYLIELRALYKVAPYFERAIVNLYTGNAEEDGETKELLLSIFNKIKTFPMHFDEKSMFAGNKIEAKTLKEEFRLHFKNISRIMDCVGCSKCRLWGKLQTQGLGTALKILFSEKEIQNLPEHSP---------SKGFQLTRHEIVALINAFARLSTSIHQLHNFRLMLKE 445
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BLAST of ERO1-like protein beta vs. Planmine SMEST
Match: SMESG000020490.1 (SMESG000020490.1)

HSP 1 Score: 978.778 bits (2529), Expect = 0.000e+0
Identity = 469/471 (99.58%), Postives = 470/471 (99.79%), Query Frame = 1 
Query:   73 MNLKYIFLLYILSLTLKDCISNAVDRCFCKLNESVDDCSCPVTDLEDYNTKIYPILQSLLVKDYFRYFKINLNRECPFWVDDSRCALRDCHVKGCGPKEIPKGLQEDDPVYIEHQKSKYFGTPNIVHHPECLDENHGGLGNLDISISQTQKEVMHNWTIYDDQQDNFCEIDDENANGATYVDLTKNPERFTGYMGKSAHRIWNSIYKENCFNEHRNKYGINLHDAEYLGFLNVIDREQCLEKRIFYRIISGLHTSISIHLCREYLLKDKTGFGSPQWGPNVTEFAKRFDPKFEKDGPQRLKNLFFTYLVELRAIAKVADYLSEDQFYTGDEVDDKETRLAVKHFLTQVKNFTNHFDEQKLFKGDPKEAKKLKHEFVQHFRNITRIINCVGCDKCKLWGTLQVKGMGTALKILFTNPATPEKTSADKDSFTKISSKFQLTRTEIVALFNAFGRLSTSVHSLSLFKDLMKDWL 1485
            MNLKYIFLLYILSLTLKDCISNAVDRCFCKLNESVDDCSCPVTDLEDYNTKIYPILQSLLVKDYFRYFKINLNRECPFWVDDSRCALRDCHVKGCGPKEIPKGLQEDDPVYIEHQKSKYFGTPNIVHHPECLDENHGGLGNLDISISQTQKEVMHNWTIYDDQQDNFCEIDDENANGATYVDLTKNPERFTGYMGKSAHRIWNSIYKENCFNEHRNKYGINLHDAEYLGFLNVIDREQCLEKRIFYRIISGLHTSISIHLCREYLLKDKTGFGSPQWGPNVTEFAKRFDPKFEKDGPQRLKNLFFTYLVELRAIAKVADYLSEDQFYTGDEVDD+ETRLAVKHFLTQVKNFTNHFDEQKLFKGDPKEAKKLKHEFVQHFRNITRIINCVGCDKCKLWGTLQVKGMGTALKILFTNPATPEK SADKDSFTKISSKFQLTRTEIVALFNAFGRLSTSVHSLSLFKDLMKDWL
Sbjct:    1 MNLKYIFLLYILSLTLKDCISNAVDRCFCKLNESVDDCSCPVTDLEDYNTKIYPILQSLLVKDYFRYFKINLNRECPFWVDDSRCALRDCHVKGCGPKEIPKGLQEDDPVYIEHQKSKYFGTPNIVHHPECLDENHGGLGNLDISISQTQKEVMHNWTIYDDQQDNFCEIDDENANGATYVDLTKNPERFTGYMGKSAHRIWNSIYKENCFNEHRNKYGINLHDAEYLGFLNVIDREQCLEKRIFYRIISGLHTSISIHLCREYLLKDKTGFGSPQWGPNVTEFAKRFDPKFEKDGPQRLKNLFFTYLVELRAIAKVADYLSEDQFYTGDEVDDRETRLAVKHFLTQVKNFTNHFDEQKLFKGDPKEAKKLKHEFVQHFRNITRIINCVGCDKCKLWGTLQVKGMGTALKILFTNPATPEKASADKDSFTKISSKFQLTRTEIVALFNAFGRLSTSVHSLSLFKDLMKDWL 471
[Close]
BLAST of ERO1-like protein beta vs. Planmine SMEST
Match: SMESG000020490.1 (SMESG000020490.1)

HSP 1 Score: 953.355 bits (2463), Expect = 0.000e+0
Identity = 460/471 (97.66%), Postives = 461/471 (97.88%), Query Frame = 1 
Query:   73 MNLKYIFLLYILSLTLKDCISNAVDRCFCKLNESVDDCSCPVTDLEDYNTKIYPILQSLLVKDYFRYFKINLNRECPFWVDDSRCALRDCHVKGCGPKEIPKGLQEDDPVYIEHQKSKYFGTPNIVHHPECLDENHGGLGNLDISISQTQKEVMHNWTIYDDQQDNFCEIDDENANGATYVDLTKNPERFTGYMGKSAHRIWNSIYKENCFNEHRNKYGINLHDAEYLGFLNVIDREQCLEKRIFYRIISGLHTSISIHLCREYLLKDKTGFGSPQWGPNVTEFAKRFDPKFEKDGPQRLKNLFFTYLVELRAIAKVADYLSEDQFYTGDEVDDKETRLAVKHFLTQVKNFTNHFDEQKLFKGDPKEAKKLKHEFVQHFRNITRIINCVGCDKCKLWGTLQVKGMGTALKILFTNPATPEKTSADKDSFTKISSKFQLTRTEIVALFNAFGRLSTSVHSLSLFKDLMKDWL 1485
            MNLKYIFLLYILSLTLKDCISNAVDRCFCKLNESVDDCSCPVTDLEDYNTKIYPILQSLLVKDYFRYFKINLNRECPFWVDDSRCALRDCHVKGCGPKEIPKGLQEDDPVYIEHQKSKYFGTPNIVHHPECLDENHGGLGNLDISISQTQKEVMHNWTIYDDQQDNFCEIDDENANGATYVDLTKNPERFTGYMGKSAHRIWNSIYKENCFNEHRNKYGINLHDA         DREQCLEKRIFYRIISGLHTSISIHLCREYLLKDKTGFGSPQWGPNVTEFAKRFDPKFEKDGPQRLKNLFFTYLVELRAIAKVADYLSEDQFYTGDEVDD+ETRLAVKHFLTQVKNFTNHFDEQKLFKGDPKEAKKLKHEFVQHFRNITRIINCVGCDKCKLWGTLQVKGMGTALKILFTNPATPEK SADKDSFTKISSKFQLTRTEIVALFNAFGRLSTSVHSLSLFKDLMKDWL
Sbjct:    1 MNLKYIFLLYILSLTLKDCISNAVDRCFCKLNESVDDCSCPVTDLEDYNTKIYPILQSLLVKDYFRYFKINLNRECPFWVDDSRCALRDCHVKGCGPKEIPKGLQEDDPVYIEHQKSKYFGTPNIVHHPECLDENHGGLGNLDISISQTQKEVMHNWTIYDDQQDNFCEIDDENANGATYVDLTKNPERFTGYMGKSAHRIWNSIYKENCFNEHRNKYGINLHDA---------DREQCLEKRIFYRIISGLHTSISIHLCREYLLKDKTGFGSPQWGPNVTEFAKRFDPKFEKDGPQRLKNLFFTYLVELRAIAKVADYLSEDQFYTGDEVDDRETRLAVKHFLTQVKNFTNHFDEQKLFKGDPKEAKKLKHEFVQHFRNITRIINCVGCDKCKLWGTLQVKGMGTALKILFTNPATPEKASADKDSFTKISSKFQLTRTEIVALFNAFGRLSTSVHSLSLFKDLMKDWL 462
The following BLAST results are available for this feature:
BLAST of ERO1-like protein beta vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ERO1B9.672e-13246.31endoplasmic reticulum oxidoreductase 1 beta [Sourc... [more]
ERO1A1.962e-12845.83endoplasmic reticulum oxidoreductase 1 alpha [Sour... [more]
ERO1B3.046e-5452.20endoplasmic reticulum oxidoreductase 1 beta [Sourc... [more]
ERO1A6.032e-4843.78endoplasmic reticulum oxidoreductase 1 alpha [Sour... [more]
ERO1A6.032e-4843.78endoplasmic reticulum oxidoreductase 1 alpha [Sour... [more]
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BLAST of ERO1-like protein beta vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ero-16.791e-11242.22Endoplasmic reticulum oxidoreductin-1 [Source:Uni... [more]
ero-16.791e-11242.22Endoplasmic reticulum oxidoreductin-1 [Source:Uni... [more]
ero-16.791e-11242.22Endoplasmic reticulum oxidoreductin-1 [Source:Uni... [more]
ero-11.779e-11142.04Endoplasmic reticulum oxidoreductin-1 [Source:Uni... [more]
ero-12.534e-10739.92Endoplasmic reticulum oxidoreductin-1 [Source:Uni... [more]
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BLAST of ERO1-like protein beta vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 1
Match NameE-valueIdentityDescription
Ero1L2.824e-13548.01gene:FBgn0261274 transcript:FBtr0073217[more]
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BLAST of ERO1-like protein beta vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ero1b2.199e-12945.80endoplasmic reticulum oxidoreductase beta [Source:... [more]
ero1a1.397e-12745.71endoplasmic reticulum oxidoreductase alpha [Source... [more]
ero1a2.971e-12745.37endoplasmic reticulum oxidoreductase alpha [Source... [more]
ero1a9.418e-12745.93endoplasmic reticulum oxidoreductase alpha [Source... [more]
ero1a2.726e-11345.87endoplasmic reticulum oxidoreductase alpha [Source... [more]
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BLAST of ERO1-like protein beta vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ero1b2.735e-13247.10endoplasmic reticulum oxidoreductase beta [Source:... [more]
ero1b7.955e-13246.68endoplasmic reticulum oxidoreductase beta [Source:... [more]
ero1a1.246e-13047.16endoplasmic reticulum oxidoreductase alpha [Source... [more]
ero1a1.464e-13047.02endoplasmic reticulum oxidoreductase alpha [Source... [more]
ero1a1.779e-12846.24endoplasmic reticulum oxidoreductase alpha [Source... [more]
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BLAST of ERO1-like protein beta vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Ero1lb2.523e-13346.65ERO1-like beta (S. cerevisiae) [Source:MGI Symbol;... [more]
Ero1lb7.683e-12846.54ERO1-like beta (S. cerevisiae) [Source:MGI Symbol;... [more]
Ero1lb1.735e-12745.91ERO1-like beta (S. cerevisiae) [Source:MGI Symbol;... [more]
Ero1l1.168e-12645.92ERO1-like (S. cerevisiae) [Source:MGI Symbol;Acc:M... [more]
Ero1l1.406e-6452.09ERO1-like (S. cerevisiae) [Source:MGI Symbol;Acc:M... [more]
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BLAST of ERO1-like protein beta vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q6DD71|ERO1A_XENLA5.970e-13646.23ERO1-like protein alpha OS=Xenopus laevis OX=8355 ... [more]
sp|Q9V3A6|ERO1L_DROME2.831e-13448.01Ero1-like protein OS=Drosophila melanogaster OX=72... [more]
sp|Q8R2E9|ERO1B_MOUSE1.765e-13246.65ERO1-like protein beta OS=Mus musculus OX=10090 GN... [more]
sp|Q86YB8|ERO1B_HUMAN4.645e-13146.31ERO1-like protein beta OS=Homo sapiens OX=9606 GN=... [more]
sp|B1H1F9|ERO1A_XENTR6.600e-13047.16ERO1-like protein alpha OS=Xenopus tropicalis OX=8... [more]
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BLAST of ERO1-like protein beta vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A2C9KB758.102e-15952.11Uncharacterized protein OS=Biomphalaria glabrata O... [more]
K1QN224.212e-15851.94ERO1-like protein beta OS=Crassostrea gigas OX=291... [more]
A0A2C9KB901.308e-15751.99Uncharacterized protein OS=Biomphalaria glabrata O... [more]
A0A2C9KB921.888e-15752.43Uncharacterized protein OS=Biomphalaria glabrata O... [more]
A0A3G4RIH82.558e-15753.76Endoplasmic reticulum oxidoreductin isoform X2 (Fr... [more]
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BLAST of ERO1-like protein beta vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 4
Match NameE-valueIdentityDescription
ero1b1.927e-13446.49endoplasmic reticulum oxidoreductase 1 beta [Sourc... [more]
ero1b4.530e-13246.46endoplasmic reticulum oxidoreductase 1 beta [Sourc... [more]
ero1a9.691e-12743.74endoplasmic reticulum oxidoreductase 1 alpha [Sour... [more]
ero1b1.041e-12445.27endoplasmic reticulum oxidoreductase 1 beta [Sourc... [more]
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BLAST of ERO1-like protein beta vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1
Match NameE-valueIdentityDescription
ero1b8.748e-5048.09endoplasmic reticulum oxidoreductase beta [Source:... [more]
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BLAST of ERO1-like protein beta vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 1
Match NameE-valueIdentityDescription
ERO16.618e-6433.86Thiol oxidase required for oxidative protein foldi... [more]
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BLAST of ERO1-like protein beta vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1
Match NameE-valueIdentityDescription
EDO485221.127e-11443.93Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of ERO1-like protein beta vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 4
Match NameE-valueIdentityDescription
ero1b5.119e-13246.49endoplasmic reticulum oxidoreductase 1 beta [Sourc... [more]
ero1b1.515e-12645.22endoplasmic reticulum oxidoreductase 1 beta [Sourc... [more]
ero1a2.225e-12443.82ERO1-like protein alpha [Source:NCBI gene;Acc:1011... [more]
ero1b2.466e-11746.84endoplasmic reticulum oxidoreductase 1 beta [Sourc... [more]
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BLAST of ERO1-like protein beta vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 2
Match NameE-valueIdentityDescription
SMESG000020490.10.000e+099.58SMESG000020490.1[more]
SMESG000020490.10.000e+097.66SMESG000020490.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30008709 ID=SMED30008709|Name=ERO1-like protein beta|organism=Schmidtea mediterranea sexual|type=transcript|length=1954bp
GTAAACTACTTAAACTTTGTTTATATTTATTAATTAATTGACGTAAATCT
AACATTTATACAAATTATTTATATGAATTTAAAATATATTTTCTTGCTAT
ACATTTTGTCATTGACACTAAAGGACTGCATATCAAATGCAGTTGACAGA
TGTTTTTGCAAATTAAATGAATCTGTAGATGATTGTAGCTGCCCCGTTAC
CGACCTGGAAGATTATAACACTAAAATATATCCTATTTTACAAAGTCTTC
TTGTTAAAGATTACTTTCGCTATTTTAAAATTAACTTAAATCGTGAATGT
CCATTCTGGGTTGATGATAGTCGATGTGCTCTAAGAGATTGTCACGTTAA
AGGTTGTGGTCCAAAAGAAATTCCTAAGGGTTTACAAGAAGACGACCCTG
TATATATAGAACACCAAAAATCAAAGTACTTTGGAACTCCGAATATAGTT
CATCACCCAGAATGTCTTGACGAAAATCATGGCGGTTTAGGCAATCTTGA
CATATCAATAAGTCAAACGCAAAAGGAGGTAATGCATAATTGGACAATTT
ATGATGACCAGCAAGATAATTTTTGCGAAATCGACGATGAAAATGCCAAC
GGAGCTACGTATGTAGATTTGACGAAAAATCCAGAAAGATTCACTGGATA
TATGGGCAAATCAGCCCACAGGATTTGGAACTCAATTTATAAAGAAAATT
GTTTCAATGAACATCGAAACAAGTATGGTATTAATTTGCACGATGCAGAG
TACCTTGGGTTTCTTAATGTAATTGACAGAGAACAATGCTTAGAGAAACG
TATTTTTTATCGAATAATCTCTGGTTTACATACTAGCATAAGTATTCATT
TGTGTCGAGAATATTTGCTAAAAGACAAGACTGGATTTGGTTCTCCTCAA
TGGGGTCCTAATGTTACTGAATTTGCCAAAAGATTTGATCCGAAATTCGA
AAAGGATGGTCCACAGAGACTTAAAAATTTGTTTTTTACATATTTAGTTG
AATTACGAGCAATAGCAAAAGTTGCTGATTATCTCAGTGAAGATCAATTT
TATACCGGTGATGAAGTTGATGACAAGGAAACCCGATTGGCTGTCAAACA
TTTTTTGACACAAGTCAAGAACTTCACAAATCATTTCGATGAGCAGAAAT
TGTTCAAAGGTGATCCAAAAGAGGCGAAGAAGCTGAAACATGAATTCGTT
CAACATTTCCGGAATATAACACGAATAATCAATTGTGTTGGTTGTGATAA
ATGTAAATTATGGGGCACTCTTCAAGTTAAAGGCATGGGTACAGCATTAA
AGATTTTATTTACAAATCCTGCAACACCAGAGAAAACATCCGCTGATAAA
GATTCATTTACTAAGATTAGTTCAAAGTTTCAGCTCACGCGTACTGAAAT
AGTTGCTTTATTCAATGCTTTCGGCCGCCTTTCTACAAGTGTTCATTCCC
TTTCACTATTCAAGGATTTGATGAAAGATTGGCTTTAAATGTCTCGAAAA
TTCCCCGCAATATTTTATAATATTATCCCATGGAGTACTTGAAACCAAAA
TTGACACCGATCAATAGTTTTATGAAATATGAATATTTTGTCACTGTTTT
GTTTACATAATTACGAATTTTATTATTATTATTTTTGTAGTTATATCAAA
TATTGAAAAGTTAAAAAAATTTTGACACGGATTTATTTTTTTCGTGTTGA
TTTGAGTGACAGTTTTAGCTCTGCTGTTCTATTTTGATTTGATTTCTGCC
ATTGTGGGCTGTGTTAACTGAGAATTTTTTCAATATTAATGTGATAAATT
GATTCGAGTCTATTATTGGAGCTTTGTCTGTGTAAAAATGTGGGAACAAA
TCACTGGAAATGTATTTATTATTATTCTGTGGTGTCTCTTGAAATTTGAA
TTCCCTGTGGATTTTTTCTGTAACAAAAATTTAAAACATTCAAATTAAAA
CAAA
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protein sequence of SMED30008709-orf-1

>SMED30008709-orf-1 ID=SMED30008709-orf-1|Name=SMED30008709-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=472bp
MNLKYIFLLYILSLTLKDCISNAVDRCFCKLNESVDDCSCPVTDLEDYNT
KIYPILQSLLVKDYFRYFKINLNRECPFWVDDSRCALRDCHVKGCGPKEI
PKGLQEDDPVYIEHQKSKYFGTPNIVHHPECLDENHGGLGNLDISISQTQ
KEVMHNWTIYDDQQDNFCEIDDENANGATYVDLTKNPERFTGYMGKSAHR
IWNSIYKENCFNEHRNKYGINLHDAEYLGFLNVIDREQCLEKRIFYRIIS
GLHTSISIHLCREYLLKDKTGFGSPQWGPNVTEFAKRFDPKFEKDGPQRL
KNLFFTYLVELRAIAKVADYLSEDQFYTGDEVDDKETRLAVKHFLTQVKN
FTNHFDEQKLFKGDPKEAKKLKHEFVQHFRNITRIINCVGCDKCKLWGTL
QVKGMGTALKILFTNPATPEKTSADKDSFTKISSKFQLTRTEIVALFNAF
GRLSTSVHSLSLFKDLMKDWL*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000070intestinal phagocyte
PLANA:0003116parenchymal cell
PLANA:0003117parapharyngeal cell
Vocabulary: INTERPRO
TermDefinition
IPR037192ERO1-like_sf
IPR007266Ero1
Vocabulary: molecular function
TermDefinition
GO:0003756protein disulfide isomerase activity
GO:0016671oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor
Vocabulary: cellular component
TermDefinition
GO:0005783endoplasmic reticulum
Vocabulary: biological process
TermDefinition
GO:0055114oxidation-reduction process
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR007266Endoplasmic reticulum oxidoreductin 1PIRSFPIRSF017205EROcoord: 1..470
e-value: 1.4E-135
score: 450.5
IPR007266Endoplasmic reticulum oxidoreductin 1PFAMPF04137ERO1coord: 51..459
e-value: 2.3E-123
score: 411.9
IPR007266Endoplasmic reticulum oxidoreductin 1PANTHERPTHR12613ERO1-RELATEDcoord: 21..466
NoneNo IPR availableSIGNALP_EUKSignalP-noTMSignalP-noTMcoord: 1..21
score: 0.642
IPR037192ERO1-like superfamilySUPERFAMILYSSF110019ERO1-likecoord: 40..470