Transcription elongation factor spt6

Overview
NameTranscription elongation factor spt6
Smed IDSMED30008708
Length (bp)583
Neoblast Clusters

Zeng et. al., 2018



 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30008708

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 16

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
pharynxSMED30008708h1SMcG0007554 Contig5500newmark_estsPMID:23079596
Forsthoefel et al., 2012		whole organism asexual adult colorimetric in situ hybridization evidence
pharynxSMED30008708h1SMcG0007554 Contig5500uc_Smed_v2PMID:23079596
Forsthoefel et al., 2012		whole organism asexual adult colorimetric in situ hybridization evidence
gutSMED30008708h1SMcG0007554 Contig5500newmark_estsPMID:23079596
Forsthoefel et al., 2012		whole organism asexual adult colorimetric in situ hybridization evidence
gutSMED30008708h1SMcG0007554 Contig5500uc_Smed_v2PMID:23079596
Forsthoefel et al., 2012		whole organism asexual adult colorimetric in situ hybridization evidence
intestinal phagocyteSMED30008708h1SMcG0007554 Contig5500newmark_estsPMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
intestinal phagocyteSMED30008708h1SMcG0007554 Contig5500uc_Smed_v2PMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
central nervous systemSMED30008708h1SMcG0007554 Contig5500newmark_estsPMID:23079596
Forsthoefel et al., 2012		whole organism asexual adult colorimetric in situ hybridization evidence
central nervous systemSMED30008708h1SMcG0007554 Contig5500uc_Smed_v2PMID:23079596
Forsthoefel et al., 2012		whole organism asexual adult colorimetric in situ hybridization evidence
pharynxSMED30008708h1SMcG0013620 Contig5500newmark_estsPMID:23079596
Forsthoefel et al., 2012		whole organism asexual adult colorimetric in situ hybridization evidence
pharynxSMED30008708h1SMcG0013620 Contig5500uc_Smed_v2PMID:23079596
Forsthoefel et al., 2012		whole organism asexual adult colorimetric in situ hybridization evidence
gutSMED30008708h1SMcG0013620 Contig5500newmark_estsPMID:23079596
Forsthoefel et al., 2012		whole organism asexual adult colorimetric in situ hybridization evidence
gutSMED30008708h1SMcG0013620 Contig5500uc_Smed_v2PMID:23079596
Forsthoefel et al., 2012		whole organism asexual adult colorimetric in situ hybridization evidence
intestinal phagocyteSMED30008708h1SMcG0013620 Contig5500newmark_estsPMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
intestinal phagocyteSMED30008708h1SMcG0013620 Contig5500uc_Smed_v2PMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
central nervous systemSMED30008708h1SMcG0013620 Contig5500newmark_estsPMID:23079596
Forsthoefel et al., 2012		whole organism asexual adult colorimetric in situ hybridization evidence
central nervous systemSMED30008708h1SMcG0013620 Contig5500uc_Smed_v2PMID:23079596
Forsthoefel et al., 2012		whole organism asexual adult colorimetric in situ hybridization evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Transcription elongation factor spt6 vs. Ensembl Human
Match: SUPT6H (SPT6 homolog, histone chaperone and transcription elongation factor [Source:HGNC Symbol;Acc:HGNC:11470])

HSP 1 Score: 93.2041 bits (230), Expect = 1.223e-21
Identity = 53/195 (27.18%), Postives = 100/195 (51.28%), Query Frame = 1 
Query:    7 PEEEAKKYISRNFPVVEKILQKARTILAYQMSREISIYNFVDSFFRKNGKIKIRPTPNGYDIIDNKHDLYKYKYITDKPLSDFEKNYDYLMINESEKDKTITFSLYLN-------DDDKTELLEKLNGLFHNDEFNTIAKAWNHQSSLVTSELVNEFLLPEIIKSSHRRLLQTGQRFLVKEIGNKLYKNINVACY 570
            P E AK Y+   FP  E +L+ AR ++A Q++RE  +   +   F++  K+ I PT  G   +D  H  Y +KY+ +KP+ +  ++  +L I  +E +  +T  + ++        +D+T   E++   ++ DEF+   + WN Q ++     + +FL  ++ K    +LL   + +++K    KLY  + VA Y
Sbjct:  566 PLELAKDYVCSQFPTPEAVLEGARYMVALQIAREPLVRQVLRQTFQERAKLNITPTKKGRKDVDEAHYAYSFKYLKNKPVKEL-RDDQFLKICLAEDEGLLTTDISIDLKGVEGYGNDQT-YFEEIKQFYYRDEFSHQVQEWNRQRTMAIERALQQFLYVQMAKELKNKLLAEAKEYVIKACSRKLYNWLRVAPY 758
[Close]
BLAST of Transcription elongation factor spt6 vs. Ensembl Human
Match: SUPT6H (SPT6 homolog, histone chaperone and transcription elongation factor [Source:HGNC Symbol;Acc:HGNC:11470])

HSP 1 Score: 93.2041 bits (230), Expect = 1.223e-21
Identity = 53/195 (27.18%), Postives = 100/195 (51.28%), Query Frame = 1 
Query:    7 PEEEAKKYISRNFPVVEKILQKARTILAYQMSREISIYNFVDSFFRKNGKIKIRPTPNGYDIIDNKHDLYKYKYITDKPLSDFEKNYDYLMINESEKDKTITFSLYLN-------DDDKTELLEKLNGLFHNDEFNTIAKAWNHQSSLVTSELVNEFLLPEIIKSSHRRLLQTGQRFLVKEIGNKLYKNINVACY 570
            P E AK Y+   FP  E +L+ AR ++A Q++RE  +   +   F++  K+ I PT  G   +D  H  Y +KY+ +KP+ +  ++  +L I  +E +  +T  + ++        +D+T   E++   ++ DEF+   + WN Q ++     + +FL  ++ K    +LL   + +++K    KLY  + VA Y
Sbjct:  566 PLELAKDYVCSQFPTPEAVLEGARYMVALQIAREPLVRQVLRQTFQERAKLNITPTKKGRKDVDEAHYAYSFKYLKNKPVKEL-RDDQFLKICLAEDEGLLTTDISIDLKGVEGYGNDQT-YFEEIKQFYYRDEFSHQVQEWNRQRTMAIERALQQFLYVQMAKELKNKLLAEAKEYVIKACSRKLYNWLRVAPY 758
[Close]
BLAST of Transcription elongation factor spt6 vs. Ensembl Celegans
Match: emb-5 (Suppressor of Ty 6 homolog [Source:UniProtKB/Swiss-Prot;Acc:P34703])

HSP 1 Score: 70.0922 bits (170), Expect = 5.298e-14
Identity = 47/195 (24.10%), Postives = 95/195 (48.72%), Query Frame = 1 
Query:    4 LPEEEAKKYISRNFPVVEKILQKARTILAYQMSREISIYNFVDSFFRKNGKIKIRPTPNGYDIIDNKHDLYKYKYITDKPLSDFEKNYDYLMINESEKDKTI-TFSLYLNDDDKTE---LLEKL--NGLFHNDEFNTIAKAWNHQSSLVTSELVNEFLLPEIIKSSHRRLLQTGQRFLVKEIGNKLYKNINVACY 570
            LP E A++Y+   F   + +L  A+ +LA ++SR+  + + V   FR++    I+PT  G D ID  H LY  +YI  KP+       ++L  +++++D  +    +Y +++D+     L+ K   + +F  DE+    + WN       +  + E L+P +    +  +L+  +  + K+   +    I+ + Y
Sbjct:  535 LPLEAAEEYVCPAFSDSDMVLNGAKFMLAKEISRQPQVRHSVRQEFRQSAHFWIKPTKKGRDTIDQTHPLYDKRYIKSKPVRSLTAE-EFLFYHKAKEDGLVDVLIMYESEEDQDSNNYLVNKYLSDSIFQKDEYTENVEQWNSVRDECVNMAITEMLVPYMRDELYNTILEEAKTAVAKKCRKEFASRISRSGY 728
[Close]
BLAST of Transcription elongation factor spt6 vs. Ensembl Fly
Match: Spt6 (gene:FBgn0028982 transcript:FBtr0070896)

HSP 1 Score: 92.4337 bits (228), Expect = 1.110e-21
Identity = 56/197 (28.43%), Postives = 99/197 (50.25%), Query Frame = 1 
Query:    7 PEEEAKKYISRNFPVVEKILQKARTILAYQMSREISIYNFVDSFFRKNGKIKIRPTPNGYDIIDNKHDLYKYKYITDKPLSD-FEKNYDYLMINESEKDKTITF-----SLYLNDDDKTELLEKLNGLFHNDEFNTIAKAWNHQSSLVTSELVNEFLLPEIIKSSHRRLLQTGQRFLVKEIGNKLYKNINVACYDNQ 579
            P E AK+Y+S  F   ++++  A+ ++A Q+++E  +   +   +    +I IRPT NG  +ID    +Y  KY+  KP+SD F   +  LM+ E EK   ITF          +    + +E+   L+  D+F    + WN   +      + ++++P++IK     L +  Q+F+++    KLYK + VA Y  Q
Sbjct:  571 PTELAKQYLSPRFMTTDEVIHAAKYVVARQLAQEPLLRKTMREVYFDRARINIRPTKNGMVLIDENSPVYSMKYVAKKPVSDLFGDQFIKLMMAEEEKLLEITFLEEFEGNACANGTPGDYVEESKALYQLDQFAKHVQEWNKLRAECVQLALQKWVIPDLIKELRSTLHEEAQQFVLRSCTGKLYKWLKVAPYKPQ 767
[Close]
BLAST of Transcription elongation factor spt6 vs. Ensembl Fly
Match: Spt6 (gene:FBgn0028982 transcript:FBtr0340027)

HSP 1 Score: 92.4337 bits (228), Expect = 1.110e-21
Identity = 56/197 (28.43%), Postives = 99/197 (50.25%), Query Frame = 1 
Query:    7 PEEEAKKYISRNFPVVEKILQKARTILAYQMSREISIYNFVDSFFRKNGKIKIRPTPNGYDIIDNKHDLYKYKYITDKPLSD-FEKNYDYLMINESEKDKTITF-----SLYLNDDDKTELLEKLNGLFHNDEFNTIAKAWNHQSSLVTSELVNEFLLPEIIKSSHRRLLQTGQRFLVKEIGNKLYKNINVACYDNQ 579
            P E AK+Y+S  F   ++++  A+ ++A Q+++E  +   +   +    +I IRPT NG  +ID    +Y  KY+  KP+SD F   +  LM+ E EK   ITF          +    + +E+   L+  D+F    + WN   +      + ++++P++IK     L +  Q+F+++    KLYK + VA Y  Q
Sbjct:  571 PTELAKQYLSPRFMTTDEVIHAAKYVVARQLAQEPLLRKTMREVYFDRARINIRPTKNGMVLIDENSPVYSMKYVAKKPVSDLFGDQFIKLMMAEEEKLLEITFLEEFEGNACANGTPGDYVEESKALYQLDQFAKHVQEWNKLRAECVQLALQKWVIPDLIKELRSTLHEEAQQFVLRSCTGKLYKWLKVAPYKPQ 767
[Close]
BLAST of Transcription elongation factor spt6 vs. Ensembl Zebrafish
Match: supt6h (SPT6 homolog, histone chaperone and transcription elongation factor [Source:NCBI gene;Acc:337866])

HSP 1 Score: 86.6557 bits (213), Expect = 1.363e-19
Identity = 52/194 (26.80%), Postives = 99/194 (51.03%), Query Frame = 1 
Query:    7 PEEEAKKYISRNFPVVEKILQKARTILAYQMSREISIYNFVDSFFRKNGKIKIRPTPNGYDIIDNKHDLYKYKYITDKPLSDFEKNYDYLMINESEKDKTITFSLYLND------DDKTELLEKLNGLFHNDEFNTIAKAWNHQSSLVTSELVNEFLLPEIIKSSHRRLLQTGQRFLVKEIGNKLYKNINVACY 570
            P E AK Y+   F   E +L+ AR ++A Q++RE  + + +   F++  KI I+PT  G   +D  H  Y +KY+ +KP+ +   +  +L +  +E++  +   + ++        D+T   +++   ++ DEF+   + WN Q +L     + +FL P++ K    +L+   +  +VK    KLY  + VA Y
Sbjct:  558 PLELAKDYVCSQFNTPEAVLEGARYMVAMQIAREPLVRHVLRQTFQERAKINIKPTKKGKKDVDEAHFAYSFKYLKNKPVKELSGD-QFLKMCLAEEEGLLAIDICIDLVGVKGYGDQT-YFDEIKQFYYRDEFSHQVQEWNKQRTLAIERSLQQFLYPQMAKELKNKLIAEAKDNIVKSCCKKLYNWLKVAPY 749
[Close]
BLAST of Transcription elongation factor spt6 vs. Ensembl Xenopus
Match: SUPT6H (SPT6 homolog, histone chaperone [Source:NCBI gene;Acc:780122])

HSP 1 Score: 94.7449 bits (234), Expect = 3.780e-22
Identity = 57/193 (29.53%), Postives = 97/193 (50.26%), Query Frame = 1 
Query:    7 PEEEAKKYISRNFPVVEKILQKARTILAYQMSREISIYNFVDSFFRKNGKIKIRPTPNGYDIIDNKHDLYKYKYITDKPLSDFEKN-YDYLMINESEKDKTITFSLYLND----DDKTELLEKLNGLFHNDEFNTIAKAWNHQSSLVTSELVNEFLLPEIIKSSHRRLLQTGQRFLVKEIGNKLYKNINVACY 570
            P E AK Y    F   E +L+ AR ++A Q++RE  +   +   F++  K+ I PT  G   ID  H  Y +KY+ +KP+ +   + +  + I E E+  TI   + + D     D+T   E++   ++ DEF+   + WN Q +L     + +FL P++ K    +L+   + F++K    KLY  + VA Y
Sbjct:  379 PLELAKDYTCSQFTTPEAVLEGARYMVALQIAREPLVRQVLRQTFQERAKVNIIPTKKGKKEIDEAHFAYAFKYLKNKPVKELRDDLFLKMCIAEEEQLLTIEICIDMKDVEGYGDQT-YFEEIKQFYYRDEFSHQVQEWNRQRTLAIERALKQFLYPQMAKELKNKLVLEAKDFVIKSCSRKLYNWLKVASY 570
[Close]
BLAST of Transcription elongation factor spt6 vs. Ensembl Xenopus
Match: SUPT6H (SPT6 homolog, histone chaperone [Source:NCBI gene;Acc:780122])

HSP 1 Score: 94.7449 bits (234), Expect = 3.816e-22
Identity = 57/193 (29.53%), Postives = 97/193 (50.26%), Query Frame = 1 
Query:    7 PEEEAKKYISRNFPVVEKILQKARTILAYQMSREISIYNFVDSFFRKNGKIKIRPTPNGYDIIDNKHDLYKYKYITDKPLSDFEKN-YDYLMINESEKDKTITFSLYLND----DDKTELLEKLNGLFHNDEFNTIAKAWNHQSSLVTSELVNEFLLPEIIKSSHRRLLQTGQRFLVKEIGNKLYKNINVACY 570
            P E AK Y    F   E +L+ AR ++A Q++RE  +   +   F++  K+ I PT  G   ID  H  Y +KY+ +KP+ +   + +  + I E E+  TI   + + D     D+T   E++   ++ DEF+   + WN Q +L     + +FL P++ K    +L+   + F++K    KLY  + VA Y
Sbjct:  560 PLELAKDYTCSQFTTPEAVLEGARYMVALQIAREPLVRQVLRQTFQERAKVNIIPTKKGKKEIDEAHFAYAFKYLKNKPVKELRDDLFLKMCIAEEEQLLTIEICIDMKDVEGYGDQT-YFEEIKQFYYRDEFSHQVQEWNRQRTLAIERALKQFLYPQMAKELKNKLVLEAKDFVIKSCSRKLYNWLKVASY 751
[Close]
BLAST of Transcription elongation factor spt6 vs. Ensembl Xenopus
Match: SUPT6H (SPT6 homolog, histone chaperone [Source:NCBI gene;Acc:780122])

HSP 1 Score: 94.7449 bits (234), Expect = 3.881e-22
Identity = 57/193 (29.53%), Postives = 97/193 (50.26%), Query Frame = 1 
Query:    7 PEEEAKKYISRNFPVVEKILQKARTILAYQMSREISIYNFVDSFFRKNGKIKIRPTPNGYDIIDNKHDLYKYKYITDKPLSDFEKN-YDYLMINESEKDKTITFSLYLND----DDKTELLEKLNGLFHNDEFNTIAKAWNHQSSLVTSELVNEFLLPEIIKSSHRRLLQTGQRFLVKEIGNKLYKNINVACY 570
            P E AK Y    F   E +L+ AR ++A Q++RE  +   +   F++  K+ I PT  G   ID  H  Y +KY+ +KP+ +   + +  + I E E+  TI   + + D     D+T   E++   ++ DEF+   + WN Q +L     + +FL P++ K    +L+   + F++K    KLY  + VA Y
Sbjct:  577 PLELAKDYTCSQFTTPEAVLEGARYMVALQIAREPLVRQVLRQTFQERAKVNIIPTKKGKKEIDEAHFAYAFKYLKNKPVKELRDDLFLKMCIAEEEQLLTIEICIDMKDVEGYGDQT-YFEEIKQFYYRDEFSHQVQEWNRQRTLAIERALKQFLYPQMAKELKNKLVLEAKDFVIKSCSRKLYNWLKVASY 768
[Close]
BLAST of Transcription elongation factor spt6 vs. Ensembl Xenopus
Match: SUPT6H (SPT6 homolog, histone chaperone [Source:NCBI gene;Acc:780122])

HSP 1 Score: 91.6633 bits (226), Expect = 3.755e-21
Identity = 55/189 (29.10%), Postives = 94/189 (49.74%), Query Frame = 1 
Query:    7 PEEEAKKYISRNFPVVEKILQKARTILAYQMSREISIYNFVDSFFRKNGKIKIRPTPNGYDIIDNKHDLYKYKYITDKPLSDFEKN-YDYLMINESEKDKTITFSLYLNDDDKTELLEKLNGLFHNDEFNTIAKAWNHQSSLVTSELVNEFLLPEIIKSSHRRLLQTGQRFLVKEIGNKLYKNINVACY 570
            P E AK Y    F   E +L+ AR ++A Q++RE  +   +   F++  K+ I PT  G   ID  H  Y +KY+ +KP+ +   + +  + I E E+  TI  S  + +       E++   ++ DEF+   + WN Q +L     + +FL P++ K    +L+   + F++K    KLY  + VA Y
Sbjct:  560 PLELAKDYTCSQFTTPEAVLEGARYMVALQIAREPLVRQVLRQTFQERAKVNIIPTKKGKKEIDEAHFAYAFKYLKNKPVKELRDDLFLKMCIAEEEQLLTIEISSIILET----YFEEIKQFYYRDEFSHQVQEWNRQRTLAIERALKQFLYPQMAKELKNKLVLEAKDFVIKSCSRKLYNWLKVASY 744
[Close]
BLAST of Transcription elongation factor spt6 vs. Ensembl Xenopus
Match: SUPT6H (SPT6 homolog, histone chaperone [Source:NCBI gene;Acc:780122])

HSP 1 Score: 81.6481 bits (200), Expect = 1.267e-17
Identity = 49/164 (29.88%), Postives = 83/164 (50.61%), Query Frame = 1 
Query:    7 PEEEAKKYISRNFPVVEKILQKARTILAYQMSREISIYNFVDSFFRKNGKIKIRPTPNGYDIIDNKHDLYKYKYITDKPLSDFEKN-YDYLMINESEKDKTITFSLYLND----DDKTELLEKLNGLFHNDEFNTIAKAWNHQSSLVTSELVNEFLLPEIIKSS 483
            P E AK Y    F   E +L+ AR ++A Q++RE  +   +   F++  K+ I PT  G   ID  H  Y +KY+ +KP+ +   + +  + I E E+  TI   + + D     D+T   E++   ++ DEF+   + WN Q +L     + +FL P++ K S
Sbjct:  561 PLELAKDYTCSQFTTPEAVLEGARYMVALQIAREPLVRQVLRQTFQERAKVNIIPTKKGKKEIDEAHFAYAFKYLKNKPVKELRDDLFLKMCIAEEEQLLTIEICIDMKDVEGYGDQT-YFEEIKQFYYRDEFSHQVQEWNRQRTLAIERALKQFLYPQMAKDS 723
[Close]
BLAST of Transcription elongation factor spt6 vs. Ensembl Mouse
Match: Supt6 (SPT6, histone chaperone and transcription elongation factor [Source:MGI Symbol;Acc:MGI:107726])

HSP 1 Score: 93.5893 bits (231), Expect = 6.057e-22
Identity = 54/195 (27.69%), Postives = 99/195 (50.77%), Query Frame = 1 
Query:    7 PEEEAKKYISRNFPVVEKILQKARTILAYQMSREISIYNFVDSFFRKNGKIKIRPTPNGYDIIDNKHDLYKYKYITDKPLSDFEKNYDYLMINESEKDKTITFSLYLN-------DDDKTELLEKLNGLFHNDEFNTIAKAWNHQSSLVTSELVNEFLLPEIIKSSHRRLLQTGQRFLVKEIGNKLYKNINVACY 570
            P E AK Y+   FP  E +L+ AR ++A Q++RE  +   +   F++  K+ I PT  G   +D  H  Y +KY+ +KP+ +  ++  +L I  +E +  +T  + ++        +D+T   E++   ++ DEF+   + WN Q ++     + +FL  ++ K    +LL   +  +VK    KLY  + VA Y
Sbjct:  566 PLELAKDYVCSQFPTPEAVLEGARYMVALQIAREPLVRQVLRQTFQERAKLNITPTKKGRKDVDEAHYAYSFKYLKNKPVKEL-RDDQFLKIGLAEDEGLLTIDISIDMKGVEGYGNDQT-YFEEIKQFYYRDEFSHQVQEWNRQRTMAIERALQQFLYVQMAKELKNKLLAEARESVVKACSRKLYNWLRVAPY 758
[Close]
BLAST of Transcription elongation factor spt6 vs. UniProt/SwissProt
Match: sp|Q62383|SPT6H_MOUSE (Transcription elongation factor SPT6 OS=Mus musculus OX=10090 GN=Supt6h PE=1 SV=2)

HSP 1 Score: 93.5893 bits (231), Expect = 4.237e-21
Identity = 54/195 (27.69%), Postives = 99/195 (50.77%), Query Frame = 1 
Query:    7 PEEEAKKYISRNFPVVEKILQKARTILAYQMSREISIYNFVDSFFRKNGKIKIRPTPNGYDIIDNKHDLYKYKYITDKPLSDFEKNYDYLMINESEKDKTITFSLYLN-------DDDKTELLEKLNGLFHNDEFNTIAKAWNHQSSLVTSELVNEFLLPEIIKSSHRRLLQTGQRFLVKEIGNKLYKNINVACY 570
            P E AK Y+   FP  E +L+ AR ++A Q++RE  +   +   F++  K+ I PT  G   +D  H  Y +KY+ +KP+ +  ++  +L I  +E +  +T  + ++        +D+T   E++   ++ DEF+   + WN Q ++     + +FL  ++ K    +LL   +  +VK    KLY  + VA Y
Sbjct:  566 PLELAKDYVCSQFPTPEAVLEGARYMVALQIAREPLVRQVLRQTFQERAKLNITPTKKGRKDVDEAHYAYSFKYLKNKPVKEL-RDDQFLKIGLAEDEGLLTIDISIDMKGVEGYGNDQT-YFEEIKQFYYRDEFSHQVQEWNRQRTMAIERALQQFLYVQMAKELKNKLLAEARESVVKACSRKLYNWLRVAPY 758
[Close]
BLAST of Transcription elongation factor spt6 vs. UniProt/SwissProt
Match: sp|Q7KZ85|SPT6H_HUMAN (Transcription elongation factor SPT6 OS=Homo sapiens OX=9606 GN=SUPT6H PE=1 SV=2)

HSP 1 Score: 93.2041 bits (230), Expect = 5.874e-21
Identity = 53/195 (27.18%), Postives = 100/195 (51.28%), Query Frame = 1 
Query:    7 PEEEAKKYISRNFPVVEKILQKARTILAYQMSREISIYNFVDSFFRKNGKIKIRPTPNGYDIIDNKHDLYKYKYITDKPLSDFEKNYDYLMINESEKDKTITFSLYLN-------DDDKTELLEKLNGLFHNDEFNTIAKAWNHQSSLVTSELVNEFLLPEIIKSSHRRLLQTGQRFLVKEIGNKLYKNINVACY 570
            P E AK Y+   FP  E +L+ AR ++A Q++RE  +   +   F++  K+ I PT  G   +D  H  Y +KY+ +KP+ +  ++  +L I  +E +  +T  + ++        +D+T   E++   ++ DEF+   + WN Q ++     + +FL  ++ K    +LL   + +++K    KLY  + VA Y
Sbjct:  566 PLELAKDYVCSQFPTPEAVLEGARYMVALQIAREPLVRQVLRQTFQERAKLNITPTKKGRKDVDEAHYAYSFKYLKNKPVKEL-RDDQFLKICLAEDEGLLTTDISIDLKGVEGYGNDQT-YFEEIKQFYYRDEFSHQVQEWNRQRTMAIERALQQFLYVQMAKELKNKLLAEAKEYVIKACSRKLYNWLRVAPY 758
[Close]
BLAST of Transcription elongation factor spt6 vs. UniProt/SwissProt
Match: sp|Q9W420|SPT6H_DROME (Transcription elongation factor SPT6 OS=Drosophila melanogaster OX=7227 GN=Spt6 PE=1 SV=1)

HSP 1 Score: 92.4337 bits (228), Expect = 1.113e-20
Identity = 56/197 (28.43%), Postives = 99/197 (50.25%), Query Frame = 1 
Query:    7 PEEEAKKYISRNFPVVEKILQKARTILAYQMSREISIYNFVDSFFRKNGKIKIRPTPNGYDIIDNKHDLYKYKYITDKPLSD-FEKNYDYLMINESEKDKTITF-----SLYLNDDDKTELLEKLNGLFHNDEFNTIAKAWNHQSSLVTSELVNEFLLPEIIKSSHRRLLQTGQRFLVKEIGNKLYKNINVACYDNQ 579
            P E AK+Y+S  F   ++++  A+ ++A Q+++E  +   +   +    +I IRPT NG  +ID    +Y  KY+  KP+SD F   +  LM+ E EK   ITF          +    + +E+   L+  D+F    + WN   +      + ++++P++IK     L +  Q+F+++    KLYK + VA Y  Q
Sbjct:  571 PTELAKQYLSPRFMTTDEVIHAAKYVVARQLAQEPLLRKTMREVYFDRARINIRPTKNGMVLIDENSPVYSMKYVAKKPVSDLFGDQFIKLMMAEEEKLLEITFLEEFEGNACANGTPGDYVEESKALYQLDQFAKHVQEWNKLRAECVQLALQKWVIPDLIKELRSTLHEEAQQFVLRSCTGKLYKWLKVAPYKPQ 767
[Close]
BLAST of Transcription elongation factor spt6 vs. UniProt/SwissProt
Match: sp|A8MS85|SPT61_ARATH (Transcription elongation factor SPT6 homolog OS=Arabidopsis thaliana OX=3702 GN=SPT6 PE=1 SV=1)

HSP 1 Score: 90.5077 bits (223), Expect = 4.984e-20
Identity = 51/190 (26.84%), Postives = 95/190 (50.00%), Query Frame = 1 
Query:    1 QLPEEEAKKYISRNFPVVEKILQKARTILAYQMSREISIYNFVDSFFRKNGKIKIRPTPNGYDIIDNKHDLYKYKYITDKPLSDFEKNYDYLMINESEKDKTITFSLYLNDDDKTELLEKLNGLFHNDEFNTIAKAWNHQSSLVTSELVNEFLLPEIIKSSHRRLLQTGQRFLVKEIGNKLYKNINVACY 570
            + PEE AK ++   F     +L+ AR + A ++S E S+  +V   + +N  +   PT +G  +ID+ H     K++ +KPLS FE    +L+I + E++K +  +  L ++    L+   N  + +   +  A+ WN Q  L+  + ++ FLLP + K +   L    +  L+ E G  L+  ++   Y
Sbjct:  513 ETPEEMAKNFVCAMFENSLAVLKGARHMAAVEISCEPSVKKYVRGIYMENAVVSTSPTADGNTVIDSFHQFSGIKWLREKPLSKFE-GAQWLLIQKGEEEKLLQVTFKLPENYMNRLISDCNEHYLSVGVSKYAQLWNEQRKLILEDALHAFLLPSMEKEARSLLTSRAKSRLLSEYGQALWNKVSAGPY 701
[Close]
BLAST of Transcription elongation factor spt6 vs. UniProt/SwissProt
Match: sp|Q9CAM1|SPT62_ARATH (Transcription elongation factor SPT6-like OS=Arabidopsis thaliana OX=3702 GN=At1g63210 PE=1 SV=2)

HSP 1 Score: 89.7373 bits (221), Expect = 1.125e-19
Identity = 51/192 (26.56%), Postives = 97/192 (50.52%), Query Frame = 1 
Query:    7 PEEEAKKYISRNFPVVEKILQKARTILAYQMSREISIYNFVDSFFRKNGKIKIRPTPNGYDIIDNKHDLYKYKYITDKPLSDFEKNYDYLMINESEKDKTITFSLYLNDDDKTELLEKLNGLFHNDEFNTIAKAWNHQSSLVTSELVNEFLLPEIIKSSHRRLLQTGQRFLVKEIGNKLYKNINVACYDNQN 582
            PEE A  Y    F   + +L+ AR + A ++S E SI  +V   F +N  +   PTP+G  +ID+ H     K++++KPL  F+    +L+I ++E++K +  +  L ++    ++ + +  + +   +  A+ WN Q  L+  + V+ F+LP + K +   L    +  L+ E G  L+  ++   Y   N
Sbjct:  432 PEEMALNYECAMFGDSQAVLKGARHMAAVEISCEPSIRKYVRGIFMENAVVSTSPTPDGNVVIDSFHRFSAVKWLSEKPLRKFD-GVQWLLIQKAEEEKLLQVTFKLPENQMNRIISECSEHYLSVGVSKYAQLWNEQRKLILEDAVHGFVLPSMEKEARSLLTSRAKTQLLSEYGQVLWNKVSSGPYRRNN 622
[Close]
BLAST of Transcription elongation factor spt6 vs. TrEMBL
Match: A0A183SRI6 (Transcription elongation factor spt6 OS=Schistocephalus solidus OX=70667 GN=SSLN_LOCUS6834 PE=3 SV=1)

HSP 1 Score: 130.183 bits (326), Expect = 2.911e-31
Identity = 66/191 (34.55%), Postives = 103/191 (53.93%), Query Frame = 1 
Query:    4 LPEEEAKKYISRNFPVVEKILQKARTILAYQMSREISIYNFVDSFFRKNGKIKIRPTPNGYDIIDNKHDLYKYKYITDKPLSDFEKNYDYLMINESEKDKTITFSLYLNDDD--KTELLEKLNGLFHNDEFNTIAKAWNHQSSLVTSELVNEFLLPEIIKSSHRRLLQTGQRFLVKEIGNKLYKNINVACY 570
            LP + A  ++   FP     L  AR +LA+Q+SRE  +             I + PTP G+ +ID  H L+  KY+ +KP+ D   +  YL I+   +D+ I F L++ ++      LL+ L   FH DEF+++ +AWN Q SL+  E V +FL P I K    +LL++ Q+ ++K    KL+K + VA Y
Sbjct:  605 LPVDAATDFVCPQFPTPASALCAARYMLAFQISREPVVRQLARRMLYTQALISLSPTPKGFKLIDEGHPLFSVKYLKNKPVLDLMGDVLYLHIHNGARDRLIKFHLHMPENQLRGLCLLDDLRHFFHQDEFSSLVEAWNEQRSLLLKEAVEQFLQPHIFKELQEKLLESSQQAVMKLCAQKLFKCLKVAPY 795
[Close]
BLAST of Transcription elongation factor spt6 vs. TrEMBL
Match: A0A0R3TN10 (Transcription elongation factor spt6 OS=Rodentolepis nana OX=102285 GN=HNAJ_LOCUS8741 PE=3 SV=2)

HSP 1 Score: 126.716 bits (317), Expect = 3.913e-30
Identity = 63/191 (32.98%), Postives = 106/191 (55.50%), Query Frame = 1 
Query:    4 LPEEEAKKYISRNFPVVEKILQKARTILAYQMSREISIYNFVDSFFRKNGKIKIRPTPNGYDIIDNKHDLYKYKYITDKPLSDFEKNYDYLMINESEKDKTITFSLYLND--DDKTELLEKLNGLFHNDEFNTIAKAWNHQSSLVTSELVNEFLLPEIIKSSHRRLLQTGQRFLVKEIGNKLYKNINVACY 570
            +P + A+ YI   FP  E +L+ AR ILAYQ++ E  +  +          I ++PTP G  IID  H L   K++ +KP+ +   N  ++ I+ + ++  IT++L+  +       LL+ L   FH DEF+ +A+AWN Q SL+  E +  F+ P IIK   R+LL++ Q+ ++    N L++ + +A Y
Sbjct:  599 MPHDAAQDYICPQFPNSESVLKAARYILAYQIAAEPIVRRWARQSLESQIVIDVKPTPKGMRIIDENHPLVSIKFLKNKPVQELMSNAIFIQIHSANREGLITYNLHALEYQQKGISLLDNLIPFFHQDEFSALAQAWNEQRSLILKEAIEAFIQPAIIKEIQRKLLESSQKTVISICSNTLFERLRIAPY 789
[Close]
BLAST of Transcription elongation factor spt6 vs. TrEMBL
Match: A0A3P7L8Y0 (S1 motif domain-containing protein (Fragment) OS=Dibothriocephalus latus OX=60516 GN=DILT_LOCUS5761 PE=4 SV=1)

HSP 1 Score: 125.946 bits (315), Expect = 7.952e-30
Identity = 66/191 (34.55%), Postives = 103/191 (53.93%), Query Frame = 1 
Query:    4 LPEEEAKKYISRNFPVVEKILQKARTILAYQMSREISIYNFVDSFFRKNGKIKIRPTPNGYDIIDNKHDLYKYKYITDKPLSDFEKNYDYLMINESEKDKTITFSLYLNDDDKTE--LLEKLNGLFHNDEFNTIAKAWNHQSSLVTSELVNEFLLPEIIKSSHRRLLQTGQRFLVKEIGNKLYKNINVACY 570
            LP + A  ++   FP     L  AR +LA+Q+SRE  +             I + PTP G+ +ID  H L+  KY+ +KP+ D   +  YL I+   +D+ I F L++ ++      LL+ L   FH DEF+++ +AWN Q SL+  E V +FL P I K    +LL++ Q+ ++K    KL+K + VA Y
Sbjct:  440 LPVDAAADFVCPQFPTAASALCAARYMLAFQISREPVVRQLARRMLYTQALISLSPTPKGFKLIDEGHPLFSVKYLKNKPVLDLMGDVLYLHIHNGARDRLIQFHLHMPENQLRGLCLLDDLRHFFHQDEFSSLVEAWNEQRSLLLKEAVEQFLQPHIFKELQEKLLESSQQAVIKLCAQKLFKCLKVAPY 630
[Close]
BLAST of Transcription elongation factor spt6 vs. TrEMBL
Match: A0A0X3P032 (Uncharacterized protein (Fragment) OS=Schistocephalus solidus OX=70667 GN=TR118607 PE=4 SV=1)

HSP 1 Score: 124.405 bits (311), Expect = 2.943e-29
Identity = 66/191 (34.55%), Postives = 103/191 (53.93%), Query Frame = 1 
Query:    4 LPEEEAKKYISRNFPVVEKILQKARTILAYQMSREISIYNFVDSFFRKNGKIKIRPTPNGYDIIDNKHDLYKYKYITDKPLSDFEKNYDYLMINESEKDKTITFSLYLNDDDKTE--LLEKLNGLFHNDEFNTIAKAWNHQSSLVTSELVNEFLLPEIIKSSHRRLLQTGQRFLVKEIGNKLYKNINVACY 570
            LP + A  ++   FP     L  AR +LA+Q+SRE  +             I + PTP G+ +ID  H L+  KY+ +KP+ D   +  YL I+   +D+ I F L++ ++      LL+ L   FH DEF+++ +AWN Q SL+  E V +FL P I K    +LL++ Q+ ++K    KL+K + VA Y
Sbjct:  635 LPVDAATDFVCPQFPTPASALCAARYMLAFQISREPVVRQLARRMLYTQALISLSPTPKGFKLIDEGHPLFSVKYLKNKPVLDLMGDVLYLHIHNGARDRLIKFHLHMPENQLRGLCLLDDLRHFFHQDEFSSLVEAWNEQRSLLLKEAVEQFLQPHIFKELQEKLLESSQQAVMKLCAQKLFKCLKVAPY 825
[Close]
BLAST of Transcription elongation factor spt6 vs. TrEMBL
Match: A0A564YV08 (Uncharacterized protein (Fragment) OS=Hymenolepis diminuta OX=6216 GN=WMSIL1_LOCUS9845 PE=4 SV=1)

HSP 1 Score: 124.02 bits (310), Expect = 3.703e-29
Identity = 61/191 (31.94%), Postives = 103/191 (53.93%), Query Frame = 1 
Query:    4 LPEEEAKKYISRNFPVVEKILQKARTILAYQMSREISIYNFVDSFFRKNGKIKIRPTPNGYDIIDNKHDLYKYKYITDKPLSDFEKNYDYLMINESEKDKTITFSLYLND--DDKTELLEKLNGLFHNDEFNTIAKAWNHQSSLVTSELVNEFLLPEIIKSSHRRLLQTGQRFLVKEIGNKLYKNINVACY 570
            +P E A+ YI   FP  E +L+ AR ILAYQ++ E  +  +          + ++PT  G  +ID  H L   K++ +KP  +   N  ++ I+ + ++  ITF+++  +       LL+ L   FH DEF+ + +AWN Q SL+  E +  FL P IIK   R+LL++ Q+ ++    N L++ + +A Y
Sbjct:  245 MPHEAAQDYICPQFPKSESVLKAARYILAYQIAAEPIVRRWARQNLESQVVVDVKPTVKGMRVIDENHPLASVKFLKNKPAQELMSNAIFIQIHSANREGLITFNIHALEYQQKGISLLDNLVSFFHQDEFSALVQAWNDQRSLILKEAIETFLQPAIIKEIQRKLLESSQKTVISICSNTLFERLRIAPY 435
[Close]
BLAST of Transcription elongation factor spt6 vs. Ensembl Cavefish
Match: supt6h (SPT6 homolog, histone chaperone and transcription elongation factor [Source:NCBI gene;Acc:103045879])

HSP 1 Score: 87.8113 bits (216), Expect = 5.556e-20
Identity = 53/195 (27.18%), Postives = 97/195 (49.74%), Query Frame = 1 
Query:    7 PEEEAKKYISRNFPVVEKILQKARTILAYQMSREISIYNFVDSFFRKNGKIKIRPTPNGYDIIDNKHDLYKYKYITDKPLSDFEKNYDYLMINESEKDKTITFSLYLN-------DDDKTELLEKLNGLFHNDEFNTIAKAWNHQSSLVTSELVNEFLLPEIIKSSHRRLLQTGQRFLVKEIGNKLYKNINVACY 570
            P E AK Y+   F   E +L+  R ++A Q++RE  + + +   F++  KI I+PT  G   ID  H  Y +KY+ +KP+ +   +  +L I  +E +  ++  + ++         D+T   +++   ++ DEF+   + WN Q  L     + +FL P++ K    +L+   +  +VK    KLY  + VA Y
Sbjct:  503 PLELAKDYVCSQFSTPEAVLEGTRYMVAMQIAREPLVRHVLRQTFQERAKINIKPTKKGKKDIDEAHYAYSFKYLKNKPVKELNGD-QFLKICMAEDEGLLSIDICIDLVGVKGYGGDQT-YFDEIKQFYYRDEFSHQVQEWNKQRMLAIERALQQFLYPQMAKELKNKLVAEAKDNIVKSCCRKLYNWLKVAPY 695
[Close]
BLAST of Transcription elongation factor spt6 vs. Ensembl Cavefish
Match: supt6h (SPT6 homolog, histone chaperone and transcription elongation factor [Source:NCBI gene;Acc:103045879])

HSP 1 Score: 87.8113 bits (216), Expect = 5.905e-20
Identity = 53/195 (27.18%), Postives = 97/195 (49.74%), Query Frame = 1 
Query:    7 PEEEAKKYISRNFPVVEKILQKARTILAYQMSREISIYNFVDSFFRKNGKIKIRPTPNGYDIIDNKHDLYKYKYITDKPLSDFEKNYDYLMINESEKDKTITFSLYLN-------DDDKTELLEKLNGLFHNDEFNTIAKAWNHQSSLVTSELVNEFLLPEIIKSSHRRLLQTGQRFLVKEIGNKLYKNINVACY 570
            P E AK Y+   F   E +L+  R ++A Q++RE  + + +   F++  KI I+PT  G   ID  H  Y +KY+ +KP+ +   +  +L I  +E +  ++  + ++         D+T   +++   ++ DEF+   + WN Q  L     + +FL P++ K    +L+   +  +VK    KLY  + VA Y
Sbjct:  574 PLELAKDYVCSQFSTPEAVLEGTRYMVAMQIAREPLVRHVLRQTFQERAKINIKPTKKGKKDIDEAHYAYSFKYLKNKPVKELNGD-QFLKICMAEDEGLLSIDICIDLVGVKGYGGDQT-YFDEIKQFYYRDEFSHQVQEWNKQRMLAIERALQQFLYPQMAKELKNKLVAEAKDNIVKSCCRKLYNWLKVAPY 766
[Close]
BLAST of Transcription elongation factor spt6 vs. Ensembl Nematostella
Match: EDO33602 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SRR7])

HSP 1 Score: 83.5741 bits (205), Expect = 4.850e-19
Identity = 49/193 (25.39%), Postives = 94/193 (48.70%), Query Frame = 1 
Query:   13 EEAKKYISRNFPVVEKILQKARTILAYQMSREISIYNFVDSFFRKNGKIKIRPTPNGYDIIDNKHDLYKYKYITDKPLSDFEKNYDYLMINESEKDKTITFSLYLNDDDKTELL-------EKLNGLFHNDEFNTIAKAWNHQSSLVTSELVNEFLLPEIIKSSHRRLLQTGQRFLVKEIGNKLYKNINVACY 570
            E A+++ +  F   +++L+  R ++A Q++R+  +   V   + K   + + PT  G   ID  H  Y +KY+  KP+ D   +  YL ++ +E +  +  S+ ++  + T  +       +++  L++ DEF+ + + WN Q     S    + L P + K    +LL   + F++K   NKL   I VA Y
Sbjct:  416 EAAEQFQTSMFATTDQVLEGTRHMVAMQIARDPLVRQCVRETYYKRATLSVSPTKKGKKEIDESHPCYTFKYLKQKPVRDLRGD-QYLKLSMAEAEGLLNISISIDIANSTGWVVNLMTYFDEVKQLYYRDEFSLLVQEWNGQRMQALSRAFYQMLYPALEKELKTKLLTESKNFVIKSCRNKLKSAIEVAPY 607
[Close]
BLAST of Transcription elongation factor spt6 vs. Ensembl Medaka
Match: supt6h (SPT6 homolog, histone chaperone and transcription elongation factor [Source:NCBI gene;Acc:101164914])

HSP 1 Score: 88.5817 bits (218), Expect = 3.145e-20
Identity = 51/195 (26.15%), Postives = 99/195 (50.77%), Query Frame = 1 
Query:    7 PEEEAKKYISRNFPVVEKILQKARTILAYQMSREISIYNFVDSFFRKNGKIKIRPTPNGYDIIDNKHDLYKYKYITDKPLSDFEKNYDYLMINESEKDKTITFSLYLN-------DDDKTELLEKLNGLFHNDEFNTIAKAWNHQSSLVTSELVNEFLLPEIIKSSHRRLLQTGQRFLVKEIGNKLYKNINVACY 570
            P E AK Y+   F   E +L   R ++A Q++RE  + + +   F++  KI I+PT  G   +D  H  Y +KY+ +KP+ +   +  +L +  +E++  +T  + ++         D+T   +++   ++ DEF+   + WN Q +L     +N+FL P++ K    +L+   +  +V+    +LY  + VA Y
Sbjct:  553 PLELAKDYVCSQFSTPENVLVGTRYMVAMQIAREPLVRHVLRQTFQERAKINIKPTKKGKKEVDEAHFAYSFKYLKNKPVKELNGD-QFLKMCLAEEEGLLTIDICIDLIGVKGYAGDQT-YFDEIKQFYYRDEFSHQVQEWNRQRTLAIERALNQFLYPQMAKELKSKLIAEAKENIVRSCCRRLYNWLKVAPY 745
[Close]
BLAST of Transcription elongation factor spt6 vs. Ensembl Medaka
Match: supt6h (SPT6 homolog, histone chaperone and transcription elongation factor [Source:NCBI gene;Acc:101164914])

HSP 1 Score: 80.8777 bits (198), Expect = 1.253e-17
Identity = 50/195 (25.64%), Postives = 97/195 (49.74%), Query Frame = 1 
Query:    7 PEEEAKKYISRNFPVVEKILQKARTILAYQMSREISIYNFVDSFFRKNGKIKIRPTPNGYDIIDNKHDLYKYKYITDKPLSDFEKNYDYLMINESEKDKTITFSLYLN-------DDDKTELLEKLNGLFHNDEFNTIAKAWNHQSSLVTSELVNEFLLPEIIKSSHRRLLQTGQRFLVKEIGNKLYKNINVACY 570
            P E AK Y+   F   E +L   R ++A Q++RE  + + +   F++  KI I+PT  G   +D  H  Y +KY+ +KP+ +   +  +L +  +E++  +T  + ++         D+T   +++   ++ DEF+   + WN Q +L     +N+FL P++ K    +L+   +  +      +LY  + VA Y
Sbjct:  491 PLELAKDYVCSQFSTPENVLVGTRYMVAMQIAREPLVRHVLRQTFQERAKINIKPTKKGKKEVDEAHFAYSFKYLKNKPVKELNGD-QFLKMCLAEEEGLLTIDICIDLIGVKGYAGDQT-YFDEIKQFYYRDEFSHQVQEWNRQRTLAIERALNQFLYPQMAKELKSKLIAEAKENI--SCCRRLYNWLKVAPY 681
[Close]
BLAST of Transcription elongation factor spt6 vs. Ensembl Medaka
Match: supt6h (SPT6 homolog, histone chaperone and transcription elongation factor [Source:NCBI gene;Acc:101164914])

HSP 1 Score: 67.3958 bits (163), Expect = 6.003e-13
Identity = 46/195 (23.59%), Postives = 87/195 (44.62%), Query Frame = 1 
Query:    7 PEEEAKKYISRNFPVVEKILQKARTILAYQMSREISIYNFVDSFFRKNGKIKIRPTPNGYDIIDNKHDLYKYKYITDKPLSDFEKNYDYLMINESEKDKTITFSLYLN-------DDDKTELLEKLNGLFHNDEFNTIAKAWNHQSSLVTSELVNEFLLPEIIKSSHRRLLQTGQRFLVKEIGNKLYKNINVACY 570
            P E AK Y+   F   E +L                        F++  KI I+PT  G   +D  H  Y +KY+ +KP+ +   +  +L +  +E++  +T  + ++         D+T   +++   ++ DEF+   + WN Q +L     +N+FL P++ K    +L+   +  +V+    +LY  + VA Y
Sbjct:  553 PLELAKDYVCSQFSTPENVLT-----------------------FQERAKINIKPTKKGKKEVDEAHFAYSFKYLKNKPVKELNGD-QFLKMCLAEEEGLLTIDICIDLIGVKGYAGDQT-YFDEIKQFYYRDEFSHQVQEWNRQRTLAIERALNQFLYPQMAKELKSKLIAEAKENIVRSCCRRLYNWLKVAPY 722
[Close]
BLAST of Transcription elongation factor spt6 vs. Planmine SMEST
Match: SMESG000059332.1 (SMESG000059332.1)

HSP 1 Score: 396.356 bits (1017), Expect = 1.937e-129
Identity = 193/194 (99.48%), Postives = 193/194 (99.48%), Query Frame = 1 
Query:    1 QLPEEEAKKYISRNFPVVEKILQKARTILAYQMSREISIYNFVDSFFRKNGKIKIRPTPNGYDIIDNKHDLYKYKYITDKPLSDFEKNYDYLMINESEKDKTITFSLYLNDDDKTELLEKLNGLFHNDEFNTIAKAWNHQSSLVTSELVNEFLLPEIIKSSHRRLLQTGQRFLVKEIGNKLYKNINVACYDNQN 582
            QLPEEEAKKYISRNFPVVEKILQKARTILAYQMSREISIYNFVDSFFRKNGKIKIRPTPNGYDIIDNKHDLYKYKYITDKPLSDFEKNYDYLMINESEKDKTITFSLYLNDDDKTELLEKLNGLFHNDEFNTIAKAWNHQSSLVTSELVNEFLLPEIIKSSHRRLLQ GQRFLVKEIGNKLYKNINVACYDNQN
Sbjct:  493 QLPEEEAKKYISRNFPVVEKILQKARTILAYQMSREISIYNFVDSFFRKNGKIKIRPTPNGYDIIDNKHDLYKYKYITDKPLSDFEKNYDYLMINESEKDKTITFSLYLNDDDKTELLEKLNGLFHNDEFNTIAKAWNHQSSLVTSELVNEFLLPEIIKSSHRRLLQNGQRFLVKEIGNKLYKNINVACYDNQN 686
[Close]
BLAST of Transcription elongation factor spt6 vs. Planmine SMEST
Match: SMESG000058110.1 (SMESG000058110.1)

HSP 1 Score: 137.117 bits (344), Expect = 2.733e-37
Identity = 66/188 (35.11%), Postives = 112/188 (59.57%), Query Frame = 1 
Query:    7 PEEEAKKYISRNFPVVEKILQKARTILAYQMSREISIYNFVDSFFRKNGKIKIRPTPNGYDIIDNKHDLYKYKYITDKPLSDFEKNYDYLMINESEKDKTITFSLYLNDDDKTELLEKLNGLFHNDEFNTIAKAWNHQSSLVTSELVNEFLLPEIIKSSHRRLLQTGQRFLVKEIGNKLYKNINVACY 570
            P + A+++I  +F   + +L+  R +LAYQ+S E  +   + + F  +G I + PT  G D ID +H LY  KY+ DKP++ F  +Y +L+I    +D  IT+ +YL +   + +L+K    FH DE+N IA+ WN Q +LV  + +++FL+P + K    RLL+  Q  L  +I +K++++INV  +
Sbjct:  497 PADAAEEFICSHFATRDLVLKGVRAMLAYQISCEPEVRKNLRNRFWHDGSITLTPTKKGKDEIDEQHPLYLMKYLLDKPINSFTDDYSFLLIENGSQDHLITYKIYLPERAYSNILDKYKSFFHRDEYNIIAQQWNEQRALVIKQALDDFLIPLVTKEMRHRLLKDAQESLTNQICDKIFQSINVQPF 684
The following BLAST results are available for this feature:
BLAST of Transcription elongation factor spt6 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 2
Match NameE-valueIdentityDescription
SUPT6H1.223e-2127.18SPT6 homolog, histone chaperone and transcription ... [more]
SUPT6H1.223e-2127.18SPT6 homolog, histone chaperone and transcription ... [more]
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BLAST of Transcription elongation factor spt6 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 1
Match NameE-valueIdentityDescription
emb-55.298e-1424.10Suppressor of Ty 6 homolog [Source:UniProtKB/Swis... [more]
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BLAST of Transcription elongation factor spt6 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 2
Match NameE-valueIdentityDescription
Spt61.110e-2128.43gene:FBgn0028982 transcript:FBtr0070896[more]
Spt61.110e-2128.43gene:FBgn0028982 transcript:FBtr0340027[more]
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BLAST of Transcription elongation factor spt6 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 1
Match NameE-valueIdentityDescription
supt6h1.363e-1926.80SPT6 homolog, histone chaperone and transcription ... [more]
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BLAST of Transcription elongation factor spt6 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
SUPT6H3.780e-2229.53SPT6 homolog, histone chaperone [Source:NCBI gene;... [more]
SUPT6H3.816e-2229.53SPT6 homolog, histone chaperone [Source:NCBI gene;... [more]
SUPT6H3.881e-2229.53SPT6 homolog, histone chaperone [Source:NCBI gene;... [more]
SUPT6H3.755e-2129.10SPT6 homolog, histone chaperone [Source:NCBI gene;... [more]
SUPT6H1.267e-1729.88SPT6 homolog, histone chaperone [Source:NCBI gene;... [more]
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BLAST of Transcription elongation factor spt6 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 1
Match NameE-valueIdentityDescription
Supt66.057e-2227.69SPT6, histone chaperone and transcription elongati... [more]
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BLAST of Transcription elongation factor spt6 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q62383|SPT6H_MOUSE4.237e-2127.69Transcription elongation factor SPT6 OS=Mus muscul... [more]
sp|Q7KZ85|SPT6H_HUMAN5.874e-2127.18Transcription elongation factor SPT6 OS=Homo sapie... [more]
sp|Q9W420|SPT6H_DROME1.113e-2028.43Transcription elongation factor SPT6 OS=Drosophila... [more]
sp|A8MS85|SPT61_ARATH4.984e-2026.84Transcription elongation factor SPT6 homolog OS=Ar... [more]
sp|Q9CAM1|SPT62_ARATH1.125e-1926.56Transcription elongation factor SPT6-like OS=Arabi... [more]
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BLAST of Transcription elongation factor spt6 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A183SRI62.911e-3134.55Transcription elongation factor spt6 OS=Schistocep... [more]
A0A0R3TN103.913e-3032.98Transcription elongation factor spt6 OS=Rodentolep... [more]
A0A3P7L8Y07.952e-3034.55S1 motif domain-containing protein (Fragment) OS=D... [more]
A0A0X3P0322.943e-2934.55Uncharacterized protein (Fragment) OS=Schistocepha... [more]
A0A564YV083.703e-2931.94Uncharacterized protein (Fragment) OS=Hymenolepis ... [more]
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BLAST of Transcription elongation factor spt6 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 2
Match NameE-valueIdentityDescription
supt6h5.556e-2027.18SPT6 homolog, histone chaperone and transcription ... [more]
supt6h5.905e-2027.18SPT6 homolog, histone chaperone and transcription ... [more]
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BLAST of Transcription elongation factor spt6 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Transcription elongation factor spt6 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Transcription elongation factor spt6 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1
Match NameE-valueIdentityDescription
EDO336024.850e-1925.39Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Transcription elongation factor spt6 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 3
Match NameE-valueIdentityDescription
supt6h3.145e-2026.15SPT6 homolog, histone chaperone and transcription ... [more]
supt6h1.253e-1725.64SPT6 homolog, histone chaperone and transcription ... [more]
supt6h6.003e-1323.59SPT6 homolog, histone chaperone and transcription ... [more]
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BLAST of Transcription elongation factor spt6 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 2
Match NameE-valueIdentityDescription
SMESG000059332.11.937e-12999.48SMESG000059332.1[more]
SMESG000058110.12.733e-3735.11SMESG000058110.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30008708 ID=SMED30008708|Name=Transcription elongation factor spt6|organism=Schmidtea mediterranea sexual|type=transcript|length=583bp
CAATTACCAGAAGAAGAAGCGAAAAAGTATATCTCCAGAAACTTTCCAGT
CGTGGAAAAGATATTGCAGAAAGCTAGAACAATTCTTGCTTATCAAATGT
CTAGGGAGATTTCTATATACAATTTTGTAGATTCCTTTTTCAGAAAGAAT
GGAAAAATCAAAATACGCCCCACTCCAAATGGCTACGATATCATTGATAA
TAAGCACGATCTGTATAAGTACAAGTATATAACTGACAAACCTCTGTCAG
ATTTCGAGAAAAATTATGATTACTTAATGATAAATGAATCAGAAAAAGAT
AAAACAATAACCTTTTCTCTCTACTTGAATGACGATGACAAAACAGAGTT
ACTTGAAAAGTTAAACGGATTATTTCACAACGATGAATTCAATACGATTG
CCAAGGCTTGGAATCATCAGAGTTCTTTAGTAACTTCAGAACTTGTGAAT
GAATTCTTATTGCCCGAGATAATTAAAAGCTCTCATCGGAGACTTTTACA
AACCGGACAACGGTTCTTGGTTAAAGAGATTGGGAATAAATTATACAAAA
ATATCAACGTAGCCTGCTATGATAATCAGAATG
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protein sequence of SMED30008708-orf-1

>SMED30008708-orf-1 ID=SMED30008708-orf-1|Name=SMED30008708-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=194bp
QLPEEEAKKYISRNFPVVEKILQKARTILAYQMSREISIYNFVDSFFRKN
GKIKIRPTPNGYDIIDNKHDLYKYKYITDKPLSDFEKNYDYLMINESEKD
KTITFSLYLNDDDKTELLEKLNGLFHNDEFNTIAKAWNHQSSLVTSELVN
EFLLPEIIKSSHRRLLQTGQRFLVKEIGNKLYKNINVACYDNQN
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: cellular component
TermDefinition
GO:0005634nucleus
Vocabulary: biological process
TermDefinition
GO:0032968positive regulation of transcription elongation from RNA polymerase II promoter
GO:0006357regulation of transcription from RNA polymerase II promoter
GO:0006414translational elongation
GO:0032784regulation of DNA-templated transcription, elongation
GO:0006139nucleobase-containing compound metabolic process
Vocabulary: INTERPRO
TermDefinition
IPR017072TF_Spt6
IPR023323Tex-like_dom_sf
Vocabulary: molecular function
TermDefinition
GO:0003676nucleic acid binding
GO:0003677DNA binding
GO:0003746translation elongation factor activity
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR023323Tex-like domain superfamilyGENE3DG3DSA:1.10.3500.10coord: 1..194
e-value: 6.9E-36
score: 126.1
IPR017072Transcription elongation factor Spt6PANTHERPTHR10145TRANSCRIPTION ELONGATION FACTOR SPT6coord: 2..192
NoneNo IPR availableSUPERFAMILYSSF158832Tex N-terminal region-likecoord: 2..185