Leucine rich repeat containing 34

Overview


Name	Leucine rich repeat containing 34
Smed ID	SMED30008679
Length (bp)	1436

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of Leucine rich repeat containing 34 (SMED30008679) t-SNE clustered cells

Violin plots show distribution of expression levels for Leucine rich repeat containing 34 (SMED30008679) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Leucine rich repeat containing 34 (SMED30008679) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Leucine rich repeat containing 34 (SMED30008679) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30008679

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 9

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
head region	SMED30008679	SMESG000053819.1	SmedASXL_012647	SmedAsxl_ww_GCZZ01	PMID:27034770 Currie et al., 2016
pharynx	SMED30008679	SMESG000053819.1	dd_Smed_v4_9926_1_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
nervous system	SMED30008679	SMESG000053819.1	dd_Smed_v4_9926_1_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
epidermis	SMED30008679	SMESG000053819.1	dd_Smed_v4_9926_1_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cephalic ganglia	SMED30008679	SMESG000053819.1	dd_Smed_v4_9926_1_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
head region	SMED30008679	SMESG000053819.1	dd_Smed_v6_9926_1_1	dd_Smed_v6	PMID:28171748 Stückemann et al., 2017
reproductive organ	SMED30008679	SMESG000053819.1	Contig42150	newmark_ests	PMID:28434803 Rouhana et al., 2017
reproductive organ	SMED30008679	SMESG000053819.1	Contig42150	uc_Smed_v2	PMID:28434803 Rouhana et al., 2017
epidermis	SMED30008679	SMESG000053819.1	dd_Smed_v4_9926_1_1	dd_Smed_v4	PMID:28292427 Wurtzel et al., 2017

Note: Hover over icons to view figure legend

Homology

[Close]

BLAST of Leucine rich repeat containing 34 vs. Ensembl Human
Match: LRRC34 (leucine rich repeat containing 34 [Source:HGNC Symbol;Acc:HGNC:28408])

HSP 1 Score: 285.419 bits (729), Expect = 1.143e-90
Identity = 155/396 (39.14%), Postives = 242/396 (61.11%), Query Frame = 2

Query:  146 ERYVQFCNEKNYEVSDFIRKVFNKEKIRLINKISDENFIYLKLCGNNKVLTKMRLTDEHIKGLCGILEEDESVKSLDLRFNRITDKGAEYIANLIKRNHSILEYNLMGNDIEEAGAKFLADAIVKSSTIKTLKMTGNKIGDFGGMQFAQAIQINESLEELDLGECDLKISSVISFATVLLCNTTLKSLNLDRPLLWTQQEETTVHMENMLYINKSLVELHLAKYEMRDFGMERLCDALIINRTLTVLDLSCNRITRDGAKILAKVLKCNTPLKVLDLGYNRIHNQGIKAIANSLSYCNTNLKCLVITFNEIHDEGLMEITAALELNTTLDKIYIWGNEFTSDAIKYFGALMDRFRLMESKVDVRPYSVDGIHQFALLPHNVDFRRYRYTAPIYGDD 1333
            + Y   C EK+ +++ FI  +  +    +   ++    I L + GNN+++   R+T E    L  IL+    +  LD+ +N + D GA Y A L+++  +++  NLM NDI   G + +A  + K+ T+K L+MTGNKI + GGM FA  +QIN SLE+LDLG+CDL + SVI+FATVL  N  +K++NL+RP+L+++QEE+TVH+  ML  N  LV LH+ K+++++ G+++LCDAL +N +L  LD+SCN+IT DG   LA VLK NT L+V+DL +NRI N G   ++ +L+  N +LK L +  N I  EGL+ ++ +++ N T   IYIWGN+F       +  L+    L     DV P+ VDG    A + + +  +++ Y    YG+ 
Sbjct:   55 KHYSNLCMEKSQKINPFILHILQEVDEEIKKGLAAG--ITLNIAGNNRLVPVERVTGEDFWILSKILKNCLYINGLDVGYNLLCDVGAYYAAKLLQKQLNLIYLNLMFNDIGPEGGELIAKVLHKNRTLKYLRMTGNKIENKGGMFFAAMLQINSSLEKLDLGDCDLGMQSVIAFATVLTQNQAIKAINLNRPILYSEQEESTVHVGRMLKENHCLVALHMCKHDIKNSGIQQLCDALYLNSSLRYLDVSCNKITHDGMVYLADVLKSNTTLEVIDLSFNRIENAGANYLSETLTSHNRSLKALSVVSNNIEGEGLVALSQSMKTNLTFSHIYIWGNKFDEATCIAYSDLIQMGCLKPDNTDVEPFVVDGRVYLAEVSNGL--KKHYYWTSTYGES 446

[Close]

BLAST of Leucine rich repeat containing 34 vs. Ensembl Human
Match: LRRC34 (leucine rich repeat containing 34 [Source:HGNC Symbol;Acc:HGNC:28408])

HSP 1 Score: 280.411 bits (716), Expect = 1.451e-89
Identity = 149/357 (41.74%), Postives = 226/357 (63.31%), Query Frame = 2

Query:  260 IYLKLCGNNKVLTKMRLTDEHIKGLCGILEEDESVKSLDLRFNRITDKGAEYIANLIKRNHSILEYNLMGNDIEEAGAKFLADAIVKSSTIKTLKMTGNKIGDFGGMQFAQAIQINESLEELDLGECDLKISSVISFATVLLCNTTLKSLNLDRPLLWTQQEETTVHMENMLYINKSLVELHLAKYEMRDFGMERLCDALIINRTLTVLDLSCNRITRDGAKILAKVLKCNTPLKVLDLGYNRIHNQGIKAIANSLSYCNTNLKCLVITFNEIHDEGLMEITAALELNTTLDKIYIWGNEFTSDAIKYFGALMDRFRLMESKVDVRPYSVDGIHQFALLPHNVDFRRYRYTAPIYGD 1330
            I L + GNN+++   R+T E    L  IL+    +  LD+ +N + D GA Y A L+++  +++  NLM NDI   G + +A  + K+ T+K L+MTGNKI + GGM FA  +QIN SLE+LDLG+CDL + SVI+FATVL  N  +K++NL+RP+L+++QEE+TVH+  ML  N  LV LH+ K+++++ G+++LCDAL +N +L  LD+SCN+IT DG   LA VLK NT L+V+DL +NRI N G   ++ +L+  N +LK L +  N I  EGL+ ++ +++ N T   IYIWGN+F       +  L+    L     DV P+ VDG    A + + +  +++ Y    YG+
Sbjct:   30 ITLNIAGNNRLVPVERVTGEDFWILSKILKNCLYINGLDVGYNLLCDVGAYYAAKLLQKQLNLIYLNLMFNDIGPEGGELIAKVLHKNRTLKYLRMTGNKIENKGGMFFAAMLQINSSLEKLDLGDCDLGMQSVIAFATVLTQNQAIKAINLNRPILYSEQEESTVHVGRMLKENHCLVALHMCKHDIKNSGIQQLCDALYLNSSLRYLDVSCNKITHDGMVYLADVLKSNTTLEVIDLSFNRIENAGANYLSETLTSHNRSLKALSVVSNNIEGEGLVALSQSMKTNLTFSHIYIWGNKFDEATCIAYSDLIQMGCLKPDNTDVEPFVVDGRVYLAEVSNGL--KKHYYWTSTYGE 384

[Close]

BLAST of Leucine rich repeat containing 34 vs. Ensembl Human
Match: LRRC34 (leucine rich repeat containing 34 [Source:HGNC Symbol;Acc:HGNC:28408])

HSP 1 Score: 233.802 bits (595), Expect = 3.777e-71
Identity = 139/395 (35.19%), Postives = 216/395 (54.68%), Query Frame = 2

Query:  146 ERYVQFCNEKNYEVSDFIRKVFNKEKIRLINKISDENFIYLKLCGNNKVLTKMRLTDEHIKGLCGILEEDESVKSLDLRFNRITDKGAEYIANLIKRNHSILEYNLMGNDIEEAGAKFLADAIVKSSTIKTLKMTGNKIGDFGGMQFAQAIQINESLEELDLGECDLKISSVISFATVLLCNTTLKSLNLDRPLLWTQQEETTVHMENMLYINKSLVELHLAKYEMRDFGMERLCDALIINRTLTVLDLSCNRITRDGAKILAKVLKCNTPLKVLDLGYNRIHNQGIKAIANSLSYCNTNLKCLVITFNEIHDEGLMEITAALELNTTLDKIYIWGNEFTSDAIKYFGALMDRFRLMESKVDVRPYSVDGIHQFALLPHNVDFRRYRYTAPIYGD 1330
            + Y   C EK+ +++ FI  +  +    +   ++    I L + GNN+++   R+T E    L  IL+    +  LD+ +N + D GA Y A L+++  +++  NLM NDI   G + +A  + K+ T+K L+MTGNKI + GGM FA  +QIN SLE+LDLG+CDL                                EE+TVH+  ML  N  LV LH+ K+++++ G+++LCDAL +N +L  LD+SCN+IT DG   LA VLK NT L+V+DL +NRI N G   ++ +L+  N +LK L +  N I  EGL+ ++ +++ N T   IYIWGN+F       +  L+    L     DV P+ VDG    A + + +  +++ Y    YG+
Sbjct:   55 KHYSNLCMEKSQKINPFILHILQEVDEEIKKGLAAG--ITLNIAGNNRLVPVERVTGEDFWILSKILKNCLYINGLDVGYNLLCDVGAYYAAKLLQKQLNLIYLNLMFNDIGPEGGELIAKVLHKNRTLKYLRMTGNKIENKGGMFFAAMLQINSSLEKLDLGDCDL--------------------------------EESTVHVGRMLKENHCLVALHMCKHDIKNSGIQQLCDALYLNSSLRYLDVSCNKITHDGMVYLADVLKSNTTLEVIDLSFNRIENAGANYLSETLTSHNRSLKALSVVSNNIEGEGLVALSQSMKTNLTFSHIYIWGNKFDEATCIAYSDLIQMGCLKPDNTDVEPFVVDGRVYLAEVSNGL--KKHYYWTSTYGE 413

[Close]

BLAST of Leucine rich repeat containing 34 vs. Ensembl Human
Match: NLRC3 (NLR family CARD domain containing 3 [Source:HGNC Symbol;Acc:HGNC:29889])

HSP 1 Score: 113.62 bits (283), Expect = 5.225e-26
Identity = 90/336 (26.79%), Postives = 151/336 (44.94%), Query Frame = 2

Query:  293 LTKMRLTDEHIKGLCGILEEDESVKSLDLRFNRITDKGAEYIANLIKRNHSILEYNLMGNDIEEAGAKFLADAIVKSSTIKTLKMTGNKIGDFGGMQFAQAIQINESLEELDLGECDLKISSVISFATVLLCNTTLKSLNLDRPLLWTQQEETTVHMENMLYINKSLVELHLAKYEMRDFGMERLCDALIINRTLTVLDLSCNRITRDGAKILAKVLKCNTPLKVLDLGYNRIHNQGIKAIANSL---------------------------SYCNTNLKCLVITFNEIHDEGLMEITAALELNTTLDKIYIWGNEFTSDAIKYFGALMDRFRLME 1219
            L + +++++  K L   L  + S+ SLDLR N I  +GA+ +A+ +K N ++   +L GN + + GA+ +A+A+  + T+  L +  N IG  G  + A A++ N SL+EL              F++  + +   K+L                     L +N+ L  L L    + D G+  L  AL  N+TL  L L  N I+ +GA+ +A  L  N+ LK LDL  N +H+QG +AIA ++                              N +L  L +  N I D+G   +  AL++NT L  +Y+      +   +  G  +   R +E
Sbjct:  720 LAENQISNKGAKALARSLLVNRSLTSLDLRGNSIGPQGAKALADALKINRTLTSLSLQGNTVRDDGARSMAEALASNRTLSMLHLQKNSIGPMGAQRMADALKQNRSLKEL-------------MFSSNSIGDGGAKAL------------------AEALKVNQGLESLDLQSNSISDAGVAALMGALCTNQTLLSLSLRENSISPEGAQAIAHALCANSTLKNLDLTANLLHDQGARAIAVAVRENRTLTSLHLQWNFIQAGAAQALGQALQLNRSLTSLDLQENAIGDDGACAVARALKVNTALTALYLQVASIGASGAQVLGEALAVNRTLE 1024

HSP 2 Score: 110.538 bits (275), Expect = 6.507e-25
Identity = 85/273 (31.14%), Postives = 137/273 (50.18%), Query Frame = 2

Query:  308 LTDEHIKGLCGILEEDESVKSLDLRFNRITDKGAEYIANLIKRNHSILEYNLMGNDIEEAGAKFLADAIVKSSTIKTLKMTGNKIGDFGGMQFAQAIQINESLEELDLGECDLKISSVISFATVLLCNTTLKSLNLDRPLLWTQQEETTVHMENMLYINKSLVELHLAKYEMRDFGMERLCDALIINRTLTVLDLSCNRITRDGAKILAKVLKCNTPLKVLDLGYNRIHNQGIKAIANSLSYCNTNLKCLVITFNEIHDEGLMEITAALELNT 1126
            + D   K L   L+ ++ ++SLDL+ N I+D G   +   +  N ++L  +L  N I   GA+ +A A+  +ST+K L +T N + D G    A A++ N +L  L L    ++  +  +    L  N +L SL+L    +    ++    +   L +N +L  L+L    +   G + L +AL +NRTL +LDL  N I   GAK LA  LK N+ L+ L+L  N +   G   IA +LS  N  L+ + +  N I D G   I+ A++ N 
Sbjct:  837 IGDGGAKALAEALKVNQGLESLDLQSNSISDAGVAALMGALCTNQTLLSLSLRENSISPEGAQAIAHALCANSTLKNLDLTANLLHDQGARAIAVAVRENRTLTSLHLQWNFIQAGAAQALGQALQLNRSLTSLDLQENAI---GDDGACAVARALKVNTALTALYLQVASIGASGAQVLGEALAVNRTLEILDLRGNAIGVAGAKALANALKVNSSLRRLNLQENSLGMDGAICIATALSG-NHRLQHINLQGNHIGDSGARMISEAIKTNA 1105

HSP 3 Score: 74.3294 bits (181), Expect = 2.639e-13
Identity = 68/247 (27.53%), Postives = 118/247 (47.77%), Query Frame = 2

Query:  236 NKISDENFIYL--KLCGNNKVLT-KMR---LTDEHIKGLCGILEEDESVKSLDLRFNRITDKGAEYIANLIKRNHSILEYNLMGNDIEEAGAKFLADAIVKSSTIKTLKMTGNKIGDFGGMQFAQAIQINESLEELDLGECDLKISSVISFATVLLCNTTLKSLNLDRPLLWTQQEETTVHMENMLYINKSLVELHLAKYEMRDFGMERLCDALIINRTLTVLDLSCNRITRDGAKILAKVLKCNTP 958
            N ISD     L   LC N  +L+  +R   ++ E  + +   L  + ++K+LDL  N + D+GA  IA  ++ N ++   +L  N I+   A+ L  A+  + ++ +L +  N IGD G    A+A+++N +L  L L    +  S        L  N TL+ L+L    +     +    + N L +N SL  L+L +  +   G   +  AL  N  L  ++L  N I   GA+++++ +K N P
Sbjct:  863 NSISDAGVAALMGALCTNQTLLSLSLRENSISPEGAQAIAHALCANSTLKNLDLTANLLHDQGARAIAVAVRENRTLTSLHLQWNFIQAGAAQALGQALQLNRSLTSLDLQENAIGDDGACAVARALKVNTALTALYLQVASIGASGAQVLGEALAVNRTLEILDLRGNAIGVAGAKA---LANALKVNSSLRRLNLQENSLGMDGAICIATALSGNHRLQHINLQGNHIGDSGARMISEAIKTNAP 1106

[Close]

BLAST of Leucine rich repeat containing 34 vs. Ensembl Human
Match: NLRC3 (NLR family CARD domain containing 3 [Source:HGNC Symbol;Acc:HGNC:29889])

HSP 1 Score: 113.235 bits (282), Expect = 6.306e-26
Identity = 90/336 (26.79%), Postives = 151/336 (44.94%), Query Frame = 2

Query:  293 LTKMRLTDEHIKGLCGILEEDESVKSLDLRFNRITDKGAEYIANLIKRNHSILEYNLMGNDIEEAGAKFLADAIVKSSTIKTLKMTGNKIGDFGGMQFAQAIQINESLEELDLGECDLKISSVISFATVLLCNTTLKSLNLDRPLLWTQQEETTVHMENMLYINKSLVELHLAKYEMRDFGMERLCDALIINRTLTVLDLSCNRITRDGAKILAKVLKCNTPLKVLDLGYNRIHNQGIKAIANSL---------------------------SYCNTNLKCLVITFNEIHDEGLMEITAALELNTTLDKIYIWGNEFTSDAIKYFGALMDRFRLME 1219
            L + +++++  K L   L  + S+ SLDLR N I  +GA+ +A+ +K N ++   +L GN + + GA+ +A+A+  + T+  L +  N IG  G  + A A++ N SL+EL              F++  + +   K+L                     L +N+ L  L L    + D G+  L  AL  N+TL  L L  N I+ +GA+ +A  L  N+ LK LDL  N +H+QG +AIA ++                              N +L  L +  N I D+G   +  AL++NT L  +Y+      +   +  G  +   R +E
Sbjct:  673 LAENQISNKGAKALARSLLVNRSLTSLDLRGNSIGPQGAKALADALKINRTLTSLSLQGNTVRDDGARSMAEALASNRTLSMLHLQKNSIGPMGAQRMADALKQNRSLKEL-------------MFSSNSIGDGGAKAL------------------AEALKVNQGLESLDLQSNSISDAGVAALMGALCTNQTLLSLSLRENSISPEGAQAIAHALCANSTLKNLDLTANLLHDQGARAIAVAVRENRTLTSLHLQWNFIQAGAAQALGQALQLNRSLTSLDLQENAIGDDGACAVARALKVNTALTALYLQVASIGASGAQVLGEALAVNRTLE 977

HSP 2 Score: 110.538 bits (275), Expect = 5.770e-25
Identity = 85/273 (31.14%), Postives = 137/273 (50.18%), Query Frame = 2

Query:  308 LTDEHIKGLCGILEEDESVKSLDLRFNRITDKGAEYIANLIKRNHSILEYNLMGNDIEEAGAKFLADAIVKSSTIKTLKMTGNKIGDFGGMQFAQAIQINESLEELDLGECDLKISSVISFATVLLCNTTLKSLNLDRPLLWTQQEETTVHMENMLYINKSLVELHLAKYEMRDFGMERLCDALIINRTLTVLDLSCNRITRDGAKILAKVLKCNTPLKVLDLGYNRIHNQGIKAIANSLSYCNTNLKCLVITFNEIHDEGLMEITAALELNT 1126
            + D   K L   L+ ++ ++SLDL+ N I+D G   +   +  N ++L  +L  N I   GA+ +A A+  +ST+K L +T N + D G    A A++ N +L  L L    ++  +  +    L  N +L SL+L    +    ++    +   L +N +L  L+L    +   G + L +AL +NRTL +LDL  N I   GAK LA  LK N+ L+ L+L  N +   G   IA +LS  N  L+ + +  N I D G   I+ A++ N 
Sbjct:  790 IGDGGAKALAEALKVNQGLESLDLQSNSISDAGVAALMGALCTNQTLLSLSLRENSISPEGAQAIAHALCANSTLKNLDLTANLLHDQGARAIAVAVRENRTLTSLHLQWNFIQAGAAQALGQALQLNRSLTSLDLQENAI---GDDGACAVARALKVNTALTALYLQVASIGASGAQVLGEALAVNRTLEILDLRGNAIGVAGAKALANALKVNSSLRRLNLQENSLGMDGAICIATALSG-NHRLQHINLQGNHIGDSGARMISEAIKTNA 1058

HSP 3 Score: 74.3294 bits (181), Expect = 2.404e-13
Identity = 68/247 (27.53%), Postives = 118/247 (47.77%), Query Frame = 2

Query:  236 NKISDENFIYL--KLCGNNKVLT-KMR---LTDEHIKGLCGILEEDESVKSLDLRFNRITDKGAEYIANLIKRNHSILEYNLMGNDIEEAGAKFLADAIVKSSTIKTLKMTGNKIGDFGGMQFAQAIQINESLEELDLGECDLKISSVISFATVLLCNTTLKSLNLDRPLLWTQQEETTVHMENMLYINKSLVELHLAKYEMRDFGMERLCDALIINRTLTVLDLSCNRITRDGAKILAKVLKCNTP 958
            N ISD     L   LC N  +L+  +R   ++ E  + +   L  + ++K+LDL  N + D+GA  IA  ++ N ++   +L  N I+   A+ L  A+  + ++ +L +  N IGD G    A+A+++N +L  L L    +  S        L  N TL+ L+L    +     +    + N L +N SL  L+L +  +   G   +  AL  N  L  ++L  N I   GA+++++ +K N P
Sbjct:  816 NSISDAGVAALMGALCTNQTLLSLSLRENSISPEGAQAIAHALCANSTLKNLDLTANLLHDQGARAIAVAVRENRTLTSLHLQWNFIQAGAAQALGQALQLNRSLTSLDLQENAIGDDGACAVARALKVNTALTALYLQVASIGASGAQVLGEALAVNRTLEILDLRGNAIGVAGAKA---LANALKVNSSLRRLNLQENSLGMDGAICIATALSGNHRLQHINLQGNHIGDSGARMISEAIKTNAP 1059

[Close]

BLAST of Leucine rich repeat containing 34 vs. Ensembl Fly
Match: CG8197 (gene:FBgn0033369 transcript:FBtr0339286)

HSP 1 Score: 58.5362 bits (140), Expect = 5.859e-9
Identity = 66/306 (21.57%), Postives = 129/306 (42.16%), Query Frame = 2

Query:  362 VKSLDLRFNRITDKGAEYIANLIKRNHSILEYNLMGNDIEEAGAKFLADAIVKSSTIKTLKMTGNKIGDFGGMQFAQAIQINESLEELDLGECDLKISSVISFATVLLCNTTLKSLNLDRPLLWTQQEETTVHMENMLYINKSLVELHLAKYEMRDFGMERLCDALIINRTLTVLDLSCNRITRDGAKILAKVLKCNTPLKVLDLGYNRIHNQGIKAIANSLSYCNTNLKCLVITFNEIHDEGLMEITAALELNTTLDKIYIWGNEFTSDAIKYFGALMDRFRLMESKVDVRPYSVDGIHQFALLP 1279
            V  L L    +TD+    +   +  + ++   N+    + +     +AD + KS  ++  +++ N++    GM  +   +               KISSV+S    LL   TL +L+L         E   +  ++M+ I +     HLA+                 N     L ++CN+I  DGA  L + +     L++LDL Y  I   G + +A  L+ C   L+ L + +N++    +  I  A++    L+K+ ++GN F S        L+D   ++ S++D+     + +  + ++P
Sbjct:  134 VSQLSLEGTPLTDEDVRILREFLLVSKTLRRLNVSSCSLTQFNFALIADGVYKSPGVR--RLSANRLL---GMSLSLDTE---------------KISSVLS---SLLMQNTLWALSL---------EHCELTAQDMIPIAE-----HLAR----------------TNSKFRRLRIACNKIGPDGAFFLLRGMSMGGNLELLDLSYCSIGTHGGEWVAKYLASCR-RLQVLHLNYNDMGPTAVNLILLAMKKQCKLEKLTLYGNHFDSRTAMIVRRLLDAEVVLHSELDISYTYDEALQDYRVVP 385

[Close]

BLAST of Leucine rich repeat containing 34 vs. Ensembl Fly
Match: CG8197 (gene:FBgn0033369 transcript:FBtr0088661)

HSP 1 Score: 58.5362 bits (140), Expect = 5.859e-9
Identity = 66/306 (21.57%), Postives = 129/306 (42.16%), Query Frame = 2

Query:  362 VKSLDLRFNRITDKGAEYIANLIKRNHSILEYNLMGNDIEEAGAKFLADAIVKSSTIKTLKMTGNKIGDFGGMQFAQAIQINESLEELDLGECDLKISSVISFATVLLCNTTLKSLNLDRPLLWTQQEETTVHMENMLYINKSLVELHLAKYEMRDFGMERLCDALIINRTLTVLDLSCNRITRDGAKILAKVLKCNTPLKVLDLGYNRIHNQGIKAIANSLSYCNTNLKCLVITFNEIHDEGLMEITAALELNTTLDKIYIWGNEFTSDAIKYFGALMDRFRLMESKVDVRPYSVDGIHQFALLP 1279
            V  L L    +TD+    +   +  + ++   N+    + +     +AD + KS  ++  +++ N++    GM  +   +               KISSV+S    LL   TL +L+L         E   +  ++M+ I +     HLA+                 N     L ++CN+I  DGA  L + +     L++LDL Y  I   G + +A  L+ C   L+ L + +N++    +  I  A++    L+K+ ++GN F S        L+D   ++ S++D+     + +  + ++P
Sbjct:  134 VSQLSLEGTPLTDEDVRILREFLLVSKTLRRLNVSSCSLTQFNFALIADGVYKSPGVR--RLSANRLL---GMSLSLDTE---------------KISSVLS---SLLMQNTLWALSL---------EHCELTAQDMIPIAE-----HLAR----------------TNSKFRRLRIACNKIGPDGAFFLLRGMSMGGNLELLDLSYCSIGTHGGEWVAKYLASCR-RLQVLHLNYNDMGPTAVNLILLAMKKQCKLEKLTLYGNHFDSRTAMIVRRLLDAEVVLHSELDISYTYDEALQDYRVVP 385

[Close]

BLAST of Leucine rich repeat containing 34 vs. Ensembl Fly
Match: RanGAP (gene:FBgn0003346 transcript:FBtr0334175)

HSP 1 Score: 49.6766 bits (117), Expect = 4.872e-6
Identity = 75/314 (23.89%), Postives = 134/314 (42.68%), Query Frame = 2

Query:  284 NKVLTKMRLTDEHIKGLCGILEEDESVKSLDLRFNRITDKGAEYIANLIKRNHSILEYNLMGN--------DIEEAGAKFLADAIVKSSTIKTLKMTGNKIGDFG--GMQFAQAIQINESLEELDLGECDL--KISSVISFATV-LLCNTTLKSLNLD-RPLLWTQ---QEETTVHMENMLYINKSLVELHLAKYEMRDFGMERLCDALIINRTLTVLDLSCNRITRDGAKILAKVLKCNTPLKVLDLGYNRIHNQGIKAIANSLSYCNTNLKCLVITFNEIHDEGLMEITAALELNTTLDKIYIWGNEFTSDA 1174
            NKVL+     D  ++ +   L +  +V  L+L  N +  + A+ I   +KR H      L  N        +I EA     A  IV  + +  L ++ N +G  G  G++      +  SL+EL L  C L  +  S++S A + L  N       L  R  + ++   ++     M       K+  E+ L +  +   G+E L ++   N  L VL+++ N +  +GA+ +A+ L     L+ +  G   I   G      +L   N  L+ + + FNEI+ +G + +  A+     L  + + GN F  + 
Sbjct:   15 NKVLSWNTAAD--VQDVVDALNKQTTVHYLNLDGNTLGVEAAKAIGEGLKR-HPEFRKALWKNMFTGRLISEIPEALKHLGAALIVAGAKLTVLDLSDNALGPNGMRGLEELLRSPVCYSLQELLLCNCGLGPEGGSMLSRALIDLHANANKAGFPLQLRVFIGSRNRLEDAGATEMATAFQTLKTFEEIVLEQNSIYIEGVEALAESFKHNPHLRVLNMNDNTLKSEGAEKIAEALPFLPLLREMSFGDCLIKTNGAYHFGEALERGNERLEVIDLGFNEINSDGGLVLVNAMGNKPKLRILNLDGNSFGEEG 325

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BLAST of Leucine rich repeat containing 34 vs. Ensembl Fly
Match: RanGAP (gene:FBgn0003346 transcript:FBtr0081234)

HSP 1 Score: 49.6766 bits (117), Expect = 5.631e-6
Identity = 75/314 (23.89%), Postives = 134/314 (42.68%), Query Frame = 2

Query:  284 NKVLTKMRLTDEHIKGLCGILEEDESVKSLDLRFNRITDKGAEYIANLIKRNHSILEYNLMGN--------DIEEAGAKFLADAIVKSSTIKTLKMTGNKIGDFG--GMQFAQAIQINESLEELDLGECDL--KISSVISFATV-LLCNTTLKSLNLD-RPLLWTQ---QEETTVHMENMLYINKSLVELHLAKYEMRDFGMERLCDALIINRTLTVLDLSCNRITRDGAKILAKVLKCNTPLKVLDLGYNRIHNQGIKAIANSLSYCNTNLKCLVITFNEIHDEGLMEITAALELNTTLDKIYIWGNEFTSDA 1174
            NKVL+     D  ++ +   L +  +V  L+L  N +  + A+ I   +KR H      L  N        +I EA     A  IV  + +  L ++ N +G  G  G++      +  SL+EL L  C L  +  S++S A + L  N       L  R  + ++   ++     M       K+  E+ L +  +   G+E L ++   N  L VL+++ N +  +GA+ +A+ L     L+ +  G   I   G      +L   N  L+ + + FNEI+ +G + +  A+     L  + + GN F  + 
Sbjct:   23 NKVLSWNTAAD--VQDVVDALNKQTTVHYLNLDGNTLGVEAAKAIGEGLKR-HPEFRKALWKNMFTGRLISEIPEALKHLGAALIVAGAKLTVLDLSDNALGPNGMRGLEELLRSPVCYSLQELLLCNCGLGPEGGSMLSRALIDLHANANKAGFPLQLRVFIGSRNRLEDAGATEMATAFQTLKTFEEIVLEQNSIYIEGVEALAESFKHNPHLRVLNMNDNTLKSEGAEKIAEALPFLPLLREMSFGDCLIKTNGAYHFGEALERGNERLEVIDLGFNEINSDGGLVLVNAMGNKPKLRILNLDGNSFGEEG 333

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BLAST of Leucine rich repeat containing 34 vs. Ensembl Fly
Match: RanGAP (gene:FBgn0003346 transcript:FBtr0334174)

HSP 1 Score: 49.6766 bits (117), Expect = 5.631e-6
Identity = 75/314 (23.89%), Postives = 134/314 (42.68%), Query Frame = 2

Query:  284 NKVLTKMRLTDEHIKGLCGILEEDESVKSLDLRFNRITDKGAEYIANLIKRNHSILEYNLMGN--------DIEEAGAKFLADAIVKSSTIKTLKMTGNKIGDFG--GMQFAQAIQINESLEELDLGECDL--KISSVISFATV-LLCNTTLKSLNLD-RPLLWTQ---QEETTVHMENMLYINKSLVELHLAKYEMRDFGMERLCDALIINRTLTVLDLSCNRITRDGAKILAKVLKCNTPLKVLDLGYNRIHNQGIKAIANSLSYCNTNLKCLVITFNEIHDEGLMEITAALELNTTLDKIYIWGNEFTSDA 1174
            NKVL+     D  ++ +   L +  +V  L+L  N +  + A+ I   +KR H      L  N        +I EA     A  IV  + +  L ++ N +G  G  G++      +  SL+EL L  C L  +  S++S A + L  N       L  R  + ++   ++     M       K+  E+ L +  +   G+E L ++   N  L VL+++ N +  +GA+ +A+ L     L+ +  G   I   G      +L   N  L+ + + FNEI+ +G + +  A+     L  + + GN F  + 
Sbjct:   23 NKVLSWNTAAD--VQDVVDALNKQTTVHYLNLDGNTLGVEAAKAIGEGLKR-HPEFRKALWKNMFTGRLISEIPEALKHLGAALIVAGAKLTVLDLSDNALGPNGMRGLEELLRSPVCYSLQELLLCNCGLGPEGGSMLSRALIDLHANANKAGFPLQLRVFIGSRNRLEDAGATEMATAFQTLKTFEEIVLEQNSIYIEGVEALAESFKHNPHLRVLNMNDNTLKSEGAEKIAEALPFLPLLREMSFGDCLIKTNGAYHFGEALERGNERLEVIDLGFNEINSDGGLVLVNAMGNKPKLRILNLDGNSFGEEG 333

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BLAST of Leucine rich repeat containing 34 vs. Ensembl Zebrafish
Match: lrrc34 (leucine rich repeat containing 34 [Source:ZFIN;Acc:ZDB-GENE-091118-73])

HSP 1 Score: 317.39 bits (812), Expect = 4.456e-104
Identity = 177/396 (44.70%), Postives = 250/396 (63.13%), Query Frame = 2

Query:  146 ERYVQFCNEKNYEVSDFIRKVFNKEKIRLINKISDENFIYLKLCGNNKVLTKMRLTDEHIKGLCGILEEDESVKSLDLRFNRITDKGAEYIANLIKRNHSILEYNLMGNDIEEAGAKFLADAIVKSSTIKTLKMTGNKIGDFGGMQFAQAIQINESLEELDLGECDLKISSVISFATVLLCNTTLKSLNLDRPLLWTQQEETTVHMENMLYINKSLVELHLAKYEMRDFGMERLCDALIINRTLTVLDLSCNRITRDGAKILAKVLKCNTPLKVLDLGYNRIHNQGIKAIANSLSYCNTNLKCLVITFNEIHDEGLMEITAALELNTTLDKIYIWGNEFTSDAIKYFGALMDRFRLMESKVDVRPYSVDGIHQFALLPHNVDFRRYRYTAPIYGDD 1333
            ERY+  C E        + +V         NK SD     LKL GN++     RLTD+ +  L   LE + ++K LDLR+N ITDKGA +IA+LI+ + S+   +LM NDIE  GA+ +A ++ K+ T+KTL+MTGNKIG+ G MQ A  +QIN +LEE+D+ +CDL   SVI+FA VL+ N  + ++N+ RPLL++ QEETTVHM  ML +N +L ELH+ K++M D G+E LC+AL  N +L  LDL CNRITRDGAK L++VLK N  L++LDL +N I + G   ++ ++   ++ LK L +T N+I   GL+ ++AA+ +N++L  IYIWGN+      + F  LM   RL++   DV PY VDG H F L   +   RR+ Y    YG D
Sbjct:    6 ERYLSVCAELQQPTHASVLEVLGN------NKSSD---CCLKLAGNDQ--PGARLTDDDMLVLTKTLEGNSAIKGLDLRYNCITDKGAVHIAHLIQDSKSLQSLDLMCNDIEADGAEVIAKSLHKNITLKTLRMTGNKIGNQGAMQLATMLQINATLEEVDVSDCDLATQSVIAFAIVLMNNKRICAINVSRPLLFSLQEETTVHMAQMLVVNNTLKELHMGKHDMTDTGVETLCEALKRNISLRYLDLCCNRITRDGAKHLSEVLKQNCSLEILDLSFNCIEDVGAIHLSEAIKLPHSKLKALSVTSNKIRKGGLLSLSAAMRVNSSLTHIYIWGNKHEEPVCEAFSGLMSSGRLLKEHTDVSPYEVDG-HVF-LAEASHGLRRHYYWTSRYGQD 388

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BLAST of Leucine rich repeat containing 34 vs. Ensembl Zebrafish
Match: lrrc34 (leucine rich repeat containing 34 [Source:ZFIN;Acc:ZDB-GENE-091118-73])

HSP 1 Score: 308.531 bits (789), Expect = 5.097e-101
Identity = 168/356 (47.19%), Postives = 237/356 (66.57%), Query Frame = 2

Query:  266 LKLCGNNKVLTKMRLTDEHIKGLCGILEEDESVKSLDLRFNRITDKGAEYIANLIKRNHSILEYNLMGNDIEEAGAKFLADAIVKSSTIKTLKMTGNKIGDFGGMQFAQAIQINESLEELDLGECDLKISSVISFATVLLCNTTLKSLNLDRPLLWTQQEETTVHMENMLYINKSLVELHLAKYEMRDFGMERLCDALIINRTLTVLDLSCNRITRDGAKILAKVLKCNTPLKVLDLGYNRIHNQGIKAIANSLSYCNTNLKCLVITFNEIHDEGLMEITAALELNTTLDKIYIWGNEFTSDAIKYFGALMDRFRLMESKVDVRPYSVDGIHQFALLPHNVDFRRYRYTAPIYGDD 1333
            LKL GN++     RLTD+ +  L   LE + ++K LDLR+N ITDKGA +IA+LI+ + S+   +LM NDIE  GA+ +A ++ K+ T+KTL+MTGNKIG+ G MQ A  +QIN +LEE+D+ +CDL   SVI+FA VL+ N  + ++N+ RPLL++ QEETTVHM  ML +N +L ELH+ K++M D G+E LC+AL  N +L  LDL CNRITRDGAK L++VLK N  L++LDL +N I + G   ++ ++   ++ LK L +T N+I   GL+ ++AA+ +N++L  IYIWGN+    A   F  LM   RL++   DV PY VDG H F L   +   RR+ Y    YG D
Sbjct:    7 LKLAGNDQ--PGARLTDDDMLVLTKTLEGNSAIKGLDLRYNCITDKGAVHIAHLIQDSKSLQSLDLMCNDIEADGAEVIAKSLHKNITLKTLRMTGNKIGNQGAMQLATMLQINATLEEVDVSDCDLATQSVIAFAIVLMNNKRICAINVSRPLLFSLQEETTVHMAQMLVVNNTLKELHMGKHDMTDTGVETLCEALKRNISLRYLDLCCNRITRDGAKHLSEVLKQNCSLEILDLSFNCIEDVGAIHLSEAIKLPHSKLKALSVTSNKIRKGGLLSLSAAMRVNSSLTHIYIWGNKHEEPA---FSGLMSSGRLLKEHTDVSPYEVDG-HVF-LAEASHGLRRHYYWTSRYGQD 355

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BLAST of Leucine rich repeat containing 34 vs. Ensembl Zebrafish
Match: nlrc3 (NLR family, CARD domain containing 3 [Source:ZFIN;Acc:ZDB-GENE-071119-1])

HSP 1 Score: 114.775 bits (286), Expect = 1.177e-26
Identity = 85/318 (26.73%), Postives = 156/318 (49.06%), Query Frame = 2

Query:  284 NKVLTKMRLTDEHI-----KGLCGILEEDESVKSLDLRFNRITDKGAEYIANLIKRNHSILEYNLMGNDIEEAGAKFLADAIVKSSTIKTLKMTGNKIGDFGGMQFAQAIQINESLEELDLGECDLKISSVISFATVLLCNTTLKSLNLDRPLLWTQQEETTVHMENMLYINKSLVELHLAKYEMRDFGMERLCDALIINRTLTVLDLSCNRITRDGAKILAKVLKCNTPLKVLDLGYNRIHNQGIKAIANSLSYCNTNLKCLVITFNEIHDEGLMEITAALELNTTLDKIYIWGNEFTSDAIKYFGALMDRFRLMES 1222
            N+ LT + L   +I     K LC  L+ ++ + S++L+ N I D+GA  ++ +++ N  +   N+  N I   G K +A+ ++K+ T++   ++ N +GD G +  AQA+ +N  L  L L    +    + + +  L  N  L  LNL    +     +    +   L +N  L EL L    + D G+  + +A+ +NR+++ L L  N +    AK LA+ L  NT +++LDL  N + + G+ A+A +L   N++L  L +        G + +  A+ +N TL  + + GN    +  K F + +   R + S
Sbjct:  369 NRTLTTLDLRGNNIGAKGAKTLCEALKLNQFLVSVNLQNNHIEDEGARSLSEVLQSNRKLTTLNVQKNGIGPEGMKKIAEGLIKNQTLQDFNVSSNHLGDLGTVALAQALMVNHVLHTLSLQSNSVSDRGIKALSHALQSNRGLCCLNLRENSIGVAGAK---DIAKALKVNTCLRELDLTANLLHDEGVTAIAEAMRVNRSISSLHLQWNFMKAGAAKALAESLSSNTCIQLLDLQENALGDNGVIALAAAL-MSNSSLTVLYLQGVSAGKSGAVALADAMVVNKTLHTLDLRGNSIGMEGAKAFSSALKNNRSLRS 682

HSP 2 Score: 100.138 bits (248), Expect = 7.276e-22
Identity = 85/292 (29.11%), Postives = 139/292 (47.60%), Query Frame = 2

Query:  362 VKSLDLRFNRITDKGAEYIANLIKRNHSILEYNLMGNDIEEAGAKFLADAIVKSSTIKTLKMTGNKIGDFGGMQFAQAIQINESLEELDLGECDLKISSVISFATVLLCNTTLKSLNLDRPLLWTQQEETTVHMENMLYINKSLVELHLAKYEMRDFGMERLCDALIINRTLTVLDLSCNRITRDGAKILAKVLKCNTPLKVLDLGYNRIHNQGI----------------------------KAIANSLSYCNTNLKCLVITFNEIHDEGLMEITAALELNTTLDKIYIWG 1153
            ++ L L  N I+ KG + ++  +  N ++   +L GN+I   GAK L +A+  +  + ++ +  N I D G    ++ +Q N  L  L++ +  +    +   A  L+ N TL+  N+    L    +  TV +   L +N  L  L L    + D G++ L  AL  NR L  L+L  N I   GAK +AK LK NT L+ LDL  N +H++G+                            KA+A SLS  NT ++ L +  N + D G++ + AAL  N++L  +Y+ G
Sbjct:  344 IQMLSLADNSISSKGVKPLSRALLVNRTLTTLDLRGNNIGAKGAKTLCEALKLNQFLVSVNLQNNHIEDEGARSLSEVLQSNRKLTTLNVQKNGIGPEGMKKIAEGLIKNQTLQDFNVSSNHL---GDLGTVALAQALMVNHVLHTLSLQSNSVSDRGIKALSHALQSNRGLCCLNLRENSIGVAGAKDIAKALKVNTCLRELDLTANLLHDEGVTAIAEAMRVNRSISSLHLQWNFMKAGAAKALAESLS-SNTCIQLLDLQENALGDNGVIALAAALMSNSSLTVLYLQG 631

HSP 3 Score: 95.5153 bits (236), Expect = 1.927e-20
Identity = 78/283 (27.56%), Postives = 136/283 (48.06%), Query Frame = 2

Query:  284 NKVLTKMRLTDEHIK-----GLCGILEEDESVKSLDLRFNRITDKGAEYIANLIKRNHSILEYNLMGNDIEEAGAKFLADAIVKSSTIKTLKMTGNKIGDFGGMQFAQAIQINESLEELDLGECDLKISSVISFATVLLCNTTLKSLNLDRPLLWTQQEETTVHMENMLYINKSLVELHLAKYEMRDFGMERLCDALIINRTLTVLDLSCNRITRDGAKILAKVLKCNTPLKVLDLGYNRIHNQGIKAIANSLSYCNTNLKCLVITFNEIHDEGLMEITAALE 1117
            N+ L    ++  H+       L   L  +  + +L L+ N ++D+G + +++ ++ N  +   NL  N I  AGAK +A A+  ++ ++ L +T N + D G    A+A+++N S+  L L    +K  +  + A  L  NT ++ L+L    L    +   + +   L  N SL  L+L        G   L DA+++N+TL  LDL  N I  +GAK  +  LK N  L+ L+L  N +   G   IA +L   N  L  + +  N I + G   ++ A++
Sbjct:  453 NQTLQDFNVSSNHLGDLGTVALAQALMVNHVLHTLSLQSNSVSDRGIKALSHALQSNRGLCCLNLRENSIGVAGAKDIAKALKVNTCLRELDLTANLLHDEGVTAIAEAMRVNRSISSLHLQWNFMKAGAAKALAESLSSNTCIQLLDLQENAL---GDNGVIALAAALMSNSSLTVLYLQGVSAGKSGAVALADAMVVNKTLHTLDLRGNSIGMEGAKAFSSALKNNRSLRSLNLQENSLGMDGAIFIATAL-RGNHQLTYINLQGNGIGESGAKVVSDAIK 731

HSP 4 Score: 72.7886 bits (177), Expect = 3.557e-13
Identity = 58/228 (25.44%), Postives = 104/228 (45.61%), Query Frame = 2

Query:  293 LTKMRLTDEHIKGLCGILEEDESVKSLDLRFNRITDKGAEYIANLIKRNHSILEYNLMGNDIEEAGAKFLADAIVKSSTIKTLKMTGNKIGDFGGMQFAQAIQINESLEELDLGECDLKISSVISFATVLLCNTTLKSLNLDRPLLWTQQEETTVHMENMLYINKSLVELHLAKYEMRDFGMERLCDALIINRTLTVLDLSCNRITRDGAKILAKVLKCNTPLKVLDL 976
            LT   L DE +  +   +  + S+ SL L++N +    A+ +A  +  N  I   +L  N + + G   LA A++ +S++  L + G   G  G +  A A+ +N++L  LDL    + +    +F++ L  N +L+SLNL         +E ++ M+  ++I                        AL  N  LT ++L  N I   GAK+++  +K   P  V+D+
Sbjct:  545 LTANLLHDEGVTAIAEAMRVNRSISSLHLQWNFMKAGAAKALAESLSSNTCIQLLDLQENALGDNGVIALAAALMSNSSLTVLYLQGVSAGKSGAVALADAMVVNKTLHTLDLRGNSIGMEGAKAFSSALKNNRSLRSLNL---------QENSLGMDGAIFI----------------------ATALRGNHQLTYINLQGNGIGESGAKVVSDAIKAGAPDCVVDI 741

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BLAST of Leucine rich repeat containing 34 vs. Ensembl Zebrafish
Match: lrrc74a (leucine rich repeat containing 74A [Source:ZFIN;Acc:ZDB-GENE-131127-263])

HSP 1 Score: 100.908 bits (250), Expect = 9.954e-23
Identity = 75/232 (32.33%), Postives = 110/232 (47.41%), Query Frame = 2

Query:  341 ILEEDESVKSLDLRFNRITDKGAEYIANLIKRNHSILEYNLMGNDIEEAGAKFLADAIVKSSTIKTLKMTGNKIGDFGGMQFAQAIQINESLEELDLGECDLKISSVISFATVLLCNTTLKSLNLDRPLLWTQQEETTVHMENMLYINKSLVELHLAKYEMRDFGME---RLCDALIINRTLTVLDLSCNRITRDGAKILAKVLKCNTPLKVLDLGYNRIHNQGIKAIANSL 1027
            +L  + ++ +LDL  N++   GAE +A ++  N SI    L GN   E  AK+ ADA+  +  +K L ++ N+    GG    Q I  N+ LE LDL    L++   ++F   L  NTTLK L+L     W                                FG E    L +AL  N TL  LDL+ NRIT +GA +L+K L+ N  L+VL L YN +  +G   + N++
Sbjct:   77 MLRANFTIHNLDLSDNQLQSAGAESVAKMLLENISIKSLKLSGNKFTEDDAKWFADALSSNYRVKELDLSHNEFSGRGGEHLGQMIANNDGLEVLDLSWNHLRMKGAVAFCAGLKVNTTLKHLDLS----WN------------------------------GFGNEGALALGEALKFNNTLQHLDLNNNRITDEGAGMLSKGLEANDTLRVLQLAYNSLTVEGALTLINTI 274

HSP 2 Score: 91.6633 bits (226), Expect = 1.557e-19
Identity = 78/247 (31.58%), Postives = 113/247 (45.75%), Query Frame = 2

Query:  434 RNHSILEYNLMGNDIEEAGAKFLADAIVKSSTIKTLKMTGNKIGDFGGMQFAQAIQINESLEELDLGECDLKISSVISFATVLLCNTTLKSLNLDRPLLWTQQEETTVHMENMLYINKSLVELHLAKYEMRDFGMERLCDALIINRTLTVLDLSCNRITRDGAKILAKVLKCNTPLKVLDLGYNRIHNQGIKAIANSLSYCNTNLKCLVITFNEIHDEGLMEITAALELNTTLDKIYIWGNEFTSDA 1174
            RN      NL  + +   G K LA A+V      TL++  N +   G     + ++ N ++  LDL +  L+ +   S A +LL N ++KSL L         E+      + L  N  + EL L+  E    G E L   +  N  L VLDLS N +   GA      LK NT LK LDL +N   N+G  A+  +L + NT L+ L +  N I DEG   ++  LE N TL  + +  N  T + 
Sbjct:   24 RNLGCATINLNHHGLGPLGGKALAIALVTDMHTTTLELADNCLRAEGATHLMEMLRANFTIHNLDLSDNQLQSAGAESVAKMLLENISIKSLKLSGNKF---TEDDAKWFADALSSNYRVKELDLSHNEFSGRGGEHLGQMIANNDGLEVLDLSWNHLRMKGAVAFCAGLKVNTTLKHLDLSWNGFGNEGALALGEALKFNNT-LQHLDLNNNRITDEGAGMLSKGLEANDTLRVLQLAYNSLTVEG 266

HSP 3 Score: 59.3066 bits (142), Expect = 4.368e-9
Identity = 40/150 (26.67%), Postives = 68/150 (45.33%), Query Frame = 2

Query:  266 LKLCGNNKVLTKMRLTDEHIKGLCGILEEDESVKSLDLRFNRITDKGAEYIANLIKRNHSILEYNLMGNDIEEAGAKFLADAIVKSSTIKTLKMTGNKIGDFGGMQFAQAIQINESLEELDLGECDLKISSVISFATVLLCNTTLKSLNL 715
            LKL GN       + T++  K     L  +  VK LDL  N  + +G E++  +I  N  +   +L  N +   GA      +  ++T+K L ++ N  G+ G +   +A++ N +L+ LDL    +        +  L  N TL+ L L
Sbjct:  115 LKLSGN-------KFTEDDAKWFADALSSNYRVKELDLSHNEFSGRGGEHLGQMIANNDGLEVLDLSWNHLRMKGAVAFCAGLKVNTTLKHLDLSWNGFGNEGALALGEALKFNNTLQHLDLNNNRITDEGAGMLSKGLEANDTLRVLQL 257

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BLAST of Leucine rich repeat containing 34 vs. Ensembl Zebrafish
Match: si:dkey-23k10.2 (si:dkey-23k10.2 [Source:ZFIN;Acc:ZDB-GENE-131122-52])

HSP 1 Score: 85.8853 bits (211), Expect = 2.844e-17
Identity = 94/354 (26.55%), Postives = 166/354 (46.89%), Query Frame = 2

Query:  293 LTKMRLTDEHIKGLCGILEEDE-SVKSLDLRFNRITDKGAEYIANLIKRNHSILE-YNLMGNDIEEAGAKFL-------------------------ADAIVK-----SSTIKTLKMTGNKIGDFGGMQFAQAIQ-INESLEELDLGECDLKISSVISFATVLLCNTT-LKSLNL-----------------DRP-----LLWTQQ----EETTVHMENMLYINK-SLVELHLAKYEMRDFGMERLCDALI-INRTLTVLDLSCNRITRDGAKILAKVLKCNTP-LKVLDLGYNRIHNQGIKAIANSLSYCNTNLKCLVITFNEIHDEGLMEITAALELNTT-LDKIYIWGNEF 1162
            LT+  + D  +K LC  LE  +  +++L L F  ++DKG +++A+ ++ N S L+  +L GN +   G K L                          DA+        S +  L ++GNK+GD G    A  +Q  +  L+ L LG+C +      + A+ L  N + L+ L+L                 + P     +L  +     EE    +   L  N  +L EL L   ++ + G++RLC +L   N TL VL L+   I+ +G   LA VL+ N   L+ LDL +N + + G++ ++++L   +  L+ L + + +I D+G   + +AL+ N + L ++Y++ N F
Sbjct:  689 LTRSAVNDSGLKLLCSGLENPQCKLETLRLEFCGVSDKGCDFLASALRSNPSHLKALDLSGNTLNFTGLKNLLAEFQKPHCKLQRLCLRLCGLTDVGCDALASVLRSDPSHLTELNLSGNKLGDLGMKLLAGGLQNPHCKLQILRLGDCSITHEGCAALASALRSNPSHLRELDLSGNKLNNAGVQILSGELENPDCNLEILRLENCDVGEEGCAALAEALKSNPLTLKELDLCWNKLGNSGVQRLCTSLENPNCTLGVLRLTGCNISENGCAALASVLRSNPSYLRDLDLSHNDLRSSGVRLLSSALEKPDCKLEILRLEYCKITDDGCAVLASALKSNPSHLRELYLYMNSF 1042

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BLAST of Leucine rich repeat containing 34 vs. Ensembl Xenopus
Match: lrrc34 (leucine rich repeat containing 34 [Source:NCBI gene;Acc:100127617])

HSP 1 Score: 343.199 bits (879), Expect = 6.464e-114
Identity = 177/397 (44.58%), Postives = 260/397 (65.49%), Query Frame = 2

Query:  146 ERYVQFCNEKNYEVSDFIRKVFNKEKIRLINKISDENFIY---LKLCGNNKVLTKMRLTDEHIKGLCGILEEDESVKSLDLRFNRITDKGAEYIANLIKRNHSILEYNLMGNDIEEAGAKFLADAIVKSSTIKTLKMTGNKIGDFGGMQFAQAIQINESLEELDLGECDLKISSVISFATVLLCNTTLKSLNLDRPLLWTQQEETTVHMENMLYINKSLVELHLAKYEMRDFGMERLCDALIINRTLTVLDLSCNRITRDGAKILAKVLKCNTPLKVLDLGYNRIHNQGIKAIANSLSYCNTNLKCLVITFNEIHDEGLMEITAALELNTTLDKIYIWGNEFTSDAIKYFGALMDRFRLMESKVDVRPYSVDGIHQFALLPHNVDFRRYRYTAPIYG 1327
            + Y + C+E+N  ++ FI ++ ++         ++E  +Y   LKLCGNN+++   R++DE    L  +L ++  + +LDLR+NR+TD GA +IA  ++ N S+L  N+MGN+I   G++ +  A+ +++T+ +L+MTGNKIG+ GGM FA  +QIN +LEELDLG+CDL I S+I+ ATVLL N TLKSLNL+RP+ +  QE+TTVH+  ML +N +L ELHL+K+E+ DFG++RLCDAL  N TL  L+LSCN+ITRDG K LA+VLK N  L++LDL  NR+ + G   +A ++   N +LK L +  N I  +GL  + AA++ N  L  IYIWGN+   +A   F  L+   RL  S  DV+PY VDG    A + H    +++ Y  P YG
Sbjct:    7 QLYTEVCSEQNQPINPFIAEILSQ---------TEEQELYASTLKLCGNNRLVQVQRVSDEDFLVLAQVLSKNSFITNLDLRYNRVTDNGAAHIATFLQNNSSVLCLNIMGNEIGTDGSEHITKALHRNTTLLSLRMTGNKIGNKGGMLFASMLQINSTLEELDLGDCDLGIQSLIALATVLLQNKTLKSLNLNRPIFYVMQEDTTVHLSEMLRVNSTLQELHLSKHEITDFGVQRLCDALHENHTLKYLNLSCNKITRDGVKYLAEVLKINKTLEILDLASNRMEDDGALYLAEAIYLYNRSLKALSVVSNNISGKGLQALAAAIKANNCLLYIYIWGNKINQEASMAFSQLLQSGRLSSSSTDVQPYVVDGRVCLAEIFHG--LKKHYYWTPSYG 392

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BLAST of Leucine rich repeat containing 34 vs. Ensembl Xenopus
Match: ENSXETT00000010017.1 (pep primary_assembly:Xenopus_tropicalis_v9.1:1:141910231:141918723:1 gene:ENSXETG00000001685.1 transcript:ENSXETT00000010017.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 85.8853 bits (211), Expect = 2.057e-17
Identity = 75/279 (26.88%), Postives = 119/279 (42.65%), Query Frame = 2

Query:  290 VLTKMRLTDEHIKGLCGILEEDESVKSLDLRFNRITDKGAEYIANLIKRNHSILEYNLMGNDIEEAGAKFLADAIVKSSTIKTLKMTGNKIGDFGGMQFAQAIQINESLEELDLGECDLKISSVISFATVLLCNTTLKSLNLDRPLLWTQQEETTVHMENMLYINKSLVELHLAKYEMRDFGMERLCDALIINRTLTVLDLSCNRITRDGAKILAKVLKCNTPLKVLDLGYNRIHNQGIKAIANSLSYCNTNLKCLVITFNEIHDEGLMEITAALELNT 1126
            V+    L  +  K L   L  +  + +LDL  N +  +GA  IA ++K N  I E +L  N +   GAK L+  +V+++T++ L ++GN+  D      ++A   N+ +E  DL        S  +  T +  NT                                ++EL+L+    R  G   +   L  N  L  +DLS N    DGA  L + LK N  L+ +++  NRI  QG    A  L   N  L+ L I+ N +  EG   I  A++ N+
Sbjct:  108 VMRHHGLGPQATKALAVTLVTNTRIVTLDLSDNWLGGEGAAAIAEMLKENCYISEIHLADNKLGVKGAKALSHMLVENTTLQKLNLSGNEFSDEAAQYISEAFMSNQKVECTDLSHNMFGEGSGETLGTAIAENT-------------------------------GMLELNLSWNNFRGKGAAAIARGLGANIFLKAIDLSYNGFGNDGAAALGEALKVNNVLEDINISNNRISVQGAVRFAMCLK-ANKTLRILKISRNPMQSEGCFAILKAIQANS 354

HSP 2 Score: 68.9366 bits (167), Expect = 6.693e-12
Identity = 62/284 (21.83%), Postives = 130/284 (45.77%), Query Frame = 2

Query:  185 VSDFIRKVFNKEKIRLINKISDE--NFIYLKLCGNNKVLTKMRLTDEHIKG-----LCGILEEDESVKSLDLRFNRITDKGAEYIANLIKRNHSILEYNLMGNDIEEAGAKFLADAIVKSSTIKTLKMTGNKIGDFGGMQFAQAIQINESLEELDLGECDLKISSVISFATVLLCNTTLKSLNLDRPLLWTQQEETTVHMENMLYINKSLVELHLAKYEMRDFGMERLCDALIINRTLTVLDLSCNRITRDGAKILAKVLKCNTPLKVLDLGYNRIHNQGIKAI 1015
            VS F+R + + E +   + +  +    + + L  N +++T + L+D  + G     +  +L+E+  +  + L  N++  KGA+ +++++  N ++ + NL GN+  +  A+++++A + +  ++   ++ N  G+  G     AI  N  + EL+L   + +     + A  L  N  LK+++                               L+     + G   L +AL +N  L  +++S NRI+  GA   A  LK N  L++L +  N + ++G  AI
Sbjct:   95 VSYFLRHLQDPELVMRHHGLGPQATKALAVTLVTNTRIVT-LDLSDNWLGGEGAAAIAEMLKENCYISEIHLADNKLGVKGAKALSHMLVENTTLQKLNLSGNEFSDEAAQYISEAFMSNQKVECTDLSHNMFGEGSGETLGTAIAENTGMLELNLSWNNFRGKGAAAIARGLGANIFLKAID-------------------------------LSYNGFGNDGAAALGEALKVNNVLEDINISNNRISVQGAVRFAMCLKANKTLRILKISRNPMQSEGCFAI 346

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BLAST of Leucine rich repeat containing 34 vs. Ensembl Xenopus
Match: NLRC3 (NLR family, CARD domain containing 3 [Source:NCBI gene;Acc:100158644])

HSP 1 Score: 82.0333 bits (201), Expect = 7.888e-16
Identity = 64/222 (28.83%), Postives = 108/222 (48.65%), Query Frame = 2

Query:  293 LTKMRLTDEHIKGLCGILEEDESVKSLDLRFNRITDKGAEYIANLIKRNHSILEYNLMGNDIEEAGAKFLADAIVKSSTIKTLKMTGNKIGDFGGMQFAQAIQINESLEELDLGECDLKISSVISFATVLLCNTTLKSLNLDRPLLWTQQEETTVHMENMLYINKSLVELHLAKYEMRDFGMERLCDALIINRTLTVLDLSCNRITRDGAKILAKVLKCNTP 958
            L + RL++  +K L   L  + ++  LDL  N I   GA  +A +++ N  +L  NL  N I   GA+ LA+++ ++ST+  L +T N + D G    A+A++ N+SLE L L   ++ +    + A  L  N TL+SLNL                EN + ++ ++                 L +A+  N +LT L L  N I + GAK+++  +K + P
Sbjct:  619 LAENRLSNRGVKALGRALMVNRTLAVLDLHSNNIGPSGAMALAEVLRSNQVLLSLNLRENSIGIEGAQALAESLRRNSTLLHLDLTANLLHDEGMEALARALRENQSLESLHLRGNNIGLRGAKALAGALKINNTLQSLNLQ---------------ENSIVLDGAIC----------------LANAVSGNSSLTSLSLQGNHIGQSGAKVISDTIKNSAP 809

HSP 2 Score: 75.0998 bits (183), Expect = 1.120e-13
Identity = 52/133 (39.10%), Postives = 76/133 (57.14%), Query Frame = 2

Query:  800 LHLAKYEMRDFGMERLCDALIINRTLTVLDLSCNRITRDGAKILAKVLKCNTPLKVLDLGYNRIHNQGIKAIANSLSYCNTNLKCLVITFNEIHDEGLMEITAALELNTTLDKIYIWGNEFTSDAIKYF-GAL 1195
            + LA+  + + G++ L  AL++NRTL VLDL  N I   GA  LA+VL+ N  L  L+L  N I  +G +A+A SL   N+ L  L +T N +HDEG+  +  AL  N +L+ +++ GN       K   GAL
Sbjct:  617 ISLAENRLSNRGVKALGRALMVNRTLAVLDLHSNNIGPSGAMALAEVLRSNQVLLSLNLRENSIGIEGAQALAESLRR-NSTLLHLDLTANLLHDEGMEALARALRENQSLESLHLRGNNIGLRGAKALAGAL 748

HSP 3 Score: 75.0998 bits (183), Expect = 1.160e-13
Identity = 70/233 (30.04%), Postives = 110/233 (47.21%), Query Frame = 2

Query:  422 NLIKRNHSILEY----NLMGNDIEEAGAKFLADAI-VKSSTIKTLKMTGNKIGDFGGMQFAQAIQINESLEELDLGECDLKISSVISFATVLLCNTTLKSLNLDRPLLWTQQEETTVHMENMLYINKSLVELHLAKYEMRDFGMERLCDALIINRTLTVLDLSCNRITRDGAKILAKVLKCNTPLKVLDLGYNRIHNQGIKAIANSLSYCNTNLKCLVITFNEIHDEGLMEIT 1105
            NL++R    L+Y     +  N  ++   + LA  +  K   I+ + +  N++ + G     +A+ +N +L  LDL   ++  S  ++ A VL  N  L SLNL    +  +  +    +   L  N +L+ L L    + D GME L  AL  N++L  L L  N I   GAK LA  LK N  L+ L+L  N I   G   +AN++S  N++L  L +  N I   G   I+
Sbjct:  573 NLVQRLLPQLQYCTNLRMENNGFQDVVMELLASILRAKDCAIQRISLAENRLSNRGVKALGRALMVNRTLAVLDLHSNNIGPSGAMALAEVLRSNQVLLSLNLRENSIGIEGAQA---LAESLRRNSTLLHLDLTANLLHDEGMEALARALRENQSLESLHLRGNNIGLRGAKALAGALKINNTLQSLNLQENSIVLDGAICLANAVSG-NSSLTSLSLQGNHIGQSGAKVIS 801

[Close]

BLAST of Leucine rich repeat containing 34 vs. Ensembl Xenopus
Match: NLRC3 (NLR family, CARD domain containing 3 [Source:NCBI gene;Acc:100158644])

HSP 1 Score: 81.2629 bits (199), Expect = 1.266e-15
Identity = 74/258 (28.68%), Postives = 121/258 (46.90%), Query Frame = 2

Query:  341 ILEEDESVKSLDLRFNRITDKGAEYIANLIK-RNHSILEYNLMGNDIEEAGAKFLADAIVKSSTIKTLKMTGNKIGDFGGMQFAQAIQINESLEELDLGECDLKISSVISFATVLLCNTTLKSLNLDRPLLWTQQEETTVHMENMLYINKSLVELHLAKYEMRDFGMERLCDAL-------IINRTLTVLDLSCNRITRDGAKILAKVLKCNTPLKVLDLGYNRIHNQGIKAIANSLSYCNTNLKCLVITFNEIHDEG 1090
            +L + +   +L +  N   D   E +A++++ ++ +I   +L  N +   G K L  A++ + T+  L +  N IG  G M  A+ ++ N+ L  L+L    +K       A  LL N  L++LNL    +  +  +    +   L  N +L+ L L    + D GME L  AL        + R++T+  L  N I   GAK LA  LK N  L+ L+L  N I   G   +AN++S  N++L  L +  N I   G
Sbjct:  638 LLPQLQYCTNLRMENNGFQDVVMELLASILRAKDCAIQRISLAENRLSNRGVKALGRALMVNRTLAVLDLHSNNIGPSGAMALAEVLRSNQVLLSLNLQNNQIKSEGAQFLAQSLLANRKLRALNLRENSIGIEGAQA---LAESLRRNSTLLHLDLTANLLHDEGMEALARALRENQSLESLQRSMTIYSLRGNNIGLRGAKALAGALKINNTLQSLNLQENSIVLDGAICLANAVSG-NSSLTSLSLQGNHIGQSG 891

HSP 2 Score: 68.1662 bits (165), Expect = 1.797e-11
Identity = 46/158 (29.11%), Postives = 86/158 (54.43%), Query Frame = 2

Query:  281 NNKVLTKMRLTDEHIKG-----LCGILEEDESVKSLDLRFNRITDKGAEYIANLIKRNHSILEYNLMGNDIEEAGAKFLADAIVKSSTIKTLK-------MTGNKIGDFGGMQFAQAIQINESLEELDLGECDLKISSVISFATVLLCNTTLKSLNLD 718
            +N+VL  + L +  IK      L   L  +  +++L+LR N I  +GA+ +A  ++RN ++L  +L  N + + G + LA A+ ++ ++++L+       + GN IG  G    A A++IN +L+ L+L E  + +   I  A  +  N++L SL+L 
Sbjct:  726 SNQVLLSLNLQNNQIKSEGAQFLAQSLLANRKLRALNLRENSIGIEGAQALAESLRRNSTLLHLDLTANLLHDEGMEALARALRENQSLESLQRSMTIYSLRGNNIGLRGAKALAGALKINNTLQSLNLQENSIVLDGAICLANAVSGNSSLTSLSLQ 883

HSP 3 Score: 64.6994 bits (156), Expect = 2.283e-10
Identity = 49/153 (32.03%), Postives = 81/153 (52.94%), Query Frame = 2

Query:  800 LHLAKYEMRDFGMERLCDALIINRTLTVLDLSCNRITRDGAKILAKVLKCNTPLKVLDLGYNRIHNQGIKAIANSLSYCNTNLKCLVITFNEIHDEGLMEITAALELNTTLDKIYIWGNEFTSDAIKYFGALMDRFRLMES-KVDVRPYSVDG 1255
            + LA+  + + G++ L  AL++NRTL VLDL  N I   GA  LA+VL+ N  L  L+L  N+I ++G + +A SL   N  L+ L +  N I  EG   +  +L  N+TL  + +  N    + ++     +   + +ES +  +  YS+ G
Sbjct:  677 ISLAENRLSNRGVKALGRALMVNRTLAVLDLHSNNIGPSGAMALAEVLRSNQVLLSLNLQNNQIKSEGAQFLAQSL-LANRKLRALNLRENSIGIEGAQALAESLRRNSTLLHLDLTANLLHDEGMEALARALRENQSLESLQRSMTIYSLRG 828

HSP 4 Score: 60.8474 bits (146), Expect = 3.228e-9
Identity = 43/123 (34.96%), Postives = 67/123 (54.47%), Query Frame = 2

Query:  773 LYINKSLVELHLAKYEMRDFGMERLCDALIINRTLTVLDLSCNRITRDGAKILAKVLKCNTPLKVLDLGYNRIHNQGIKAIANSLSYCNTNLKCLVITFNEIHDEGLMEITAALELNTTLDKI 1141
            L +N++L  L L    +   G   L + L  N+ L  L+L  N+I  +GA+ LA+ L  N  L+ L+L  N I  +G +A+A SL   N+ L  L +T N +HDEG+  +  AL  N +L+ +
Sbjct:  696 LMVNRTLAVLDLHSNNIGPSGAMALAEVLRSNQVLLSLNLQNNQIKSEGAQFLAQSLLANRKLRALNLRENSIGIEGAQALAESLRR-NSTLLHLDLTANLLHDEGMEALARALRENQSLESL 817

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BLAST of Leucine rich repeat containing 34 vs. Ensembl Xenopus
Match: hcn4 (hyperpolarization activated cyclic nucleotide gated potassium channel 4 [Source:Xenbase;Acc:XB-GENE-940130])

HSP 1 Score: 70.8626 bits (172), Expect = 1.626e-12
Identity = 64/255 (25.10%), Postives = 108/255 (42.35%), Query Frame = 2

Query:  230 LINKISDENFIY-LKLCGNNKVLTKMRLTDEHIKGLCGILEEDESVKSLDLRFNRITDKGAEYIANLIKRNHSILEYNLMGNDIEEAGAKFLADAIVKSSTIKTLKMTGNKIGDFGGMQFAQAIQINESLEELDLGECDLKISSVISFATVLLCNTTLKSLNLDRPLLWTQQEETTVHMENMLYINKSLVELHLAKYEMRDFGMERLCDALIINRTLTVLDLSCNRITRDGAKILAKVLKCNTPLKVLDLGYNRI 991
            L+  + + + +Y ++ CG N      R TD     L   L    ++K   L  +++ D  A  +   +  + +++  +L  N + + GA+ +A  ++K S ++ L ++ N +G  G    A A+  N +L  L L     +++ V +     LCN  L                           N++L ELHL   E+ +     L  AL  N +L  L L+CNRI  DG K L + +  N  L  LDL    I
Sbjct:  207 LLPGLEELHLVYGVRNCGMNFEWNLFRFTDRDCNSLAQALRVFRNLKVFRLHKSKVDDDKACVLVRSLLNHPALVHLDLSHNQVSDRGARAIAK-LLKESALRVLDLSNNNVGAHGAQALAHALTNNWTLRNLSL-----RLNHVGNEGGQALCNALLP--------------------------NQTLQELHLGSNELSEPTASALSQALTHNGSLRRLSLACNRIGPDGGKQLLEGMSDNETLLELDLRLTEI 429

[Close]

BLAST of Leucine rich repeat containing 34 vs. Ensembl Mouse
Match: Lrrc34 (leucine rich repeat containing 34 [Source:MGI Symbol;Acc:MGI:1919077])

HSP 1 Score: 304.679 bits (779), Expect = 4.954e-99
Identity = 165/394 (41.88%), Postives = 241/394 (61.17%), Query Frame = 2

Query:  149 RYVQFCNEKNYEVSDFIRKVFNKEKIRLINKISDENFIYLKLCGNNKVLTKMRLTDEHIKGLCGILEEDESVKSLDLRFNRITDKGAEYIANLIKRNHSILEYNLMGNDIEEAGAKFLADAIVKSSTIKTLKMTGNKIGDFGGMQFAQAIQINESLEELDLGECDLKISSVISFATVLLCNTTLKSLNLDRPLLWTQQEETTVHMENMLYINKSLVELHLAKYEMRDFGMERLCDALIINRTLTVLDLSCNRITRDGAKILAKVLKCNTPLKVLDLGYNRIHNQGIKAIANSLSYCNTNLKCLVITFNEIHDEGLMEITAALELNTTLDKIYIWGNEFTSDAIKYFGALMDRFRLMESKVDVRPYSVDGIHQFALLPHNVDFRRYRYTAPIYGD 1330
            +Y   C+E   + + FI  +  K     I K   E F  + + GNN++ +  R+T E    L   L     +  +D+R+N I D GA Y A L+++  SI   NLM NDI   G + +A A+ K+ T+K L+MTGNKI + GGM FA  +Q+N SLE+LDLG+CDL +  VI+F+TVL  N  +K +NL+RP+L+ +QEE+TVH+ +ML  N  LVELH+ K+ M+++G+++LC+AL +N +L  LD+SCN+ITRDG   LA VLK NT L+VLDL +NRI   G K ++ +L+  N +LK L +  N+I  EGL+ ++ +++ N  L  IYIWGN+F  D    +  L+   RL     DV PY VD      L   +   +R+ Y AP YG+
Sbjct:    7 QYCYLCSENIRKTNPFILNILQKLD-EEIEKRPKEKFT-VNIAGNNRLDSGQRITGEDFWLLSKTLRNQPCISGVDVRYNLIGDVGAFYAAKLLQKQPSITYLNLMFNDIGPEGGELIAKALHKNKTLKYLRMTGNKIENTGGMLFAAMLQMNSSLEKLDLGDCDLGLQCVIAFSTVLTQNQAIKGINLNRPILYGEQEESTVHIGHMLKENHVLVELHMCKHGMKNYGLQQLCNALYLNSSLRYLDVSCNKITRDGMVFLADVLKSNTTLEVLDLSFNRIETAGAKYLSETLTSHNRSLKALSVVSNKIEGEGLVALSQSMKTNLVLSNIYIWGNKFDEDTCVAYSDLIKSGRLKPDNTDVEPYMVD--EHIYLSEVSNGLKRHYYWAPTYGE 396

[Close]

BLAST of Leucine rich repeat containing 34 vs. Ensembl Mouse
Match: Nlrc3 (NLR family, CARD domain containing 3 [Source:MGI Symbol;Acc:MGI:2444070])

HSP 1 Score: 113.62 bits (283), Expect = 3.444e-26
Identity = 87/278 (31.29%), Postives = 134/278 (48.20%), Query Frame = 2

Query:  326 KGLCGILEEDESVKSLDLRFNRITDKGAEYIANLIKRNHSILEYNLMGNDIEEAGAKFLADAIVKSSTIKTLKMTGNKIGDFGGMQFAQAIQINESLEELDLGECDLKISSVISFATVLLCNTTLKSLNLDRPLLWTQQEETTVHMENMLYINKSLVELHLAKYEMRDFGMERLCDALIINRTLTVLDLSCNRITRDGAKILAKVLKCNTPLKVLDLGYNRIHNQGIKAIANSLSYCNTNLKCLVITFNEIHDEGLMEITAALELNTTLDKIYIWGNE 1159
            K L   L+ + ++ SL L+ N I D G   +A  +  N +I    L  N I   GA+ +ADA+ ++ ++K L  + N IGD G +  A+A+++N+ LE LDL    +    V      L  N TL SLNL    +     E    +   L  N +L  L L    + D G + +  A+  N +LT L L  N I    A+ L + L+ N  L  LDL  N I ++G  ++A +L   NT L  L +    I  +G   +  AL +N TL+ + + GN+
Sbjct:  749 KALADALKINRTLTSLSLQSNVIKDDGVMCVAEALVSNQTISMLQLQKNLIGLIGAQQMADALKQNRSLKALMFSSNTIGDRGAIALAEALKVNQILENLDLQSNSISDMGVTVLMRALCSNQTLSSLNLRENSI---SPEGAQALTQALCRNNTLKHLDLTANLLHDRGAQAIAVAVGENHSLTHLHLQWNFIQAGAARALGQALQLNRTLTTLDLQENAIGDEGASSVAGALKV-NTTLIALYLQVASIGSQGAQALGEALTVNRTLEILDLRGND 1022

HSP 2 Score: 110.923 bits (276), Expect = 3.041e-25
Identity = 93/317 (29.34%), Postives = 150/317 (47.32%), Query Frame = 2

Query:  350 EDESVKSLDLRFNRITDKGAEYIANLIKRNHSILEYNLMGNDIEEAGAKFLADAIVKSSTIKTLKMTGNKIGDFGGMQFAQAIQINESLEELDLGECDLKISSVISFATVLLCNTTLKSLNLDRPLLWTQQEETTVHMENMLYINKSLVELHLAKYEMRDFGMERLCDALIINRTLTVLDLSCNRITRDGAKILAKVLKCNTPLKVLDLGYNRIHNQGIKAIA------NSLSY---------------------CNTNLKCLVITFNEIHDEGLMEITAALELNTTLDKIYIWGNEFTSDAIKYFGALMDRFRLME 1219
            +D  ++ + L  N+I +KGA+ +A  +  N S++  +L  N I   GAK LADA+  + T+ +L +  N I D G M  A+A+  N+++  L L +  + +      A  L  N +LK+L        T  +   + +   L +N+ L  L L    + D G+  L  AL  N+TL+ L+L  N I+ +GA+ L + L  N  LK LDL  N +H++G +AIA      +SL++                      N  L  L +  N I DEG   +  AL++NTTL  +Y+      S   +  G  +   R +E
Sbjct:  701 KDCRIRKISLAENQIGNKGAKALARSLLVNRSLITLDLRSNSIGPPGAKALADALKINRTLTSLSLQSNVIKDDGVMCVAEALVSNQTISMLQLQKNLIGLIGAQQMADALKQNRSLKALMFSSN---TIGDRGAIALAEALKVNQILENLDLQSNSISDMGVTVLMRALCSNQTLSSLNLRENSISPEGAQALTQALCRNNTLKHLDLTANLLHDRGAQAIAVAVGENHSLTHLHLQWNFIQAGAARALGQALQLNRTLTTLDLQENAIGDEGASSVAGALKVNTTLIALYLQVASIGSQGAQALGEALTVNRTLE 1014

HSP 3 Score: 77.7962 bits (190), Expect = 1.228e-14
Identity = 74/268 (27.61%), Postives = 125/268 (46.64%), Query Frame = 2

Query:  323 IKGLCGILEEDESVKSLDLRFNRITDKGAEYIANLIKRNHSILEYNLMGNDIEEAGAKFLADAIVKSSTIKTLKMTGNKIGDFGGMQFAQAIQINESLEELDLGECDLKISSVISFATVLLCNTTLKSLNLDRPLLWTQQEETTVHMENMLYINKSLVELHLAKYEMRDFGMERLCDALIINRTLTVLDLSCNRITRDGAKILAKVLKCNTPLKVLDLGYNRIHNQGIKAIANSLSYCNTNLKCLVITFNEIHDEGLMEITAALELNT 1126
            ++ LC     ++++ SL+LR N I+ +GA+ +   + RN+++   +L  N + + GA+ +A A+ ++ ++  L +  N I         QA+Q+N +L  LDL E  +      S A  L  NTT                               L+ L+L    +   G + L +AL +NRTL +LDL  N +   GAK LA  LK N+ L+ L+L  N +   G   +A++LS  N  L  + +  N I +     I+ A++ N 
Sbjct:  864 MRALC----SNQTLSSLNLRENSISPEGAQALTQALCRNNTLKHLDLTANLLHDRGAQAIAVAVGENHSLTHLHLQWNFIQAGAARALGQALQLNRTLTTLDLQENAIGDEGASSVAGALKVNTT-------------------------------LIALYLQVASIGSQGAQALGEALTVNRTLEILDLRGNDVGAAGAKALANALKLNSSLRRLNLQENSLGMDGAIFVASALSE-NHGLHHINLQGNPIGESAARMISEAIKTNA 1095

HSP 4 Score: 77.411 bits (189), Expect = 1.669e-14
Identity = 68/247 (27.53%), Postives = 112/247 (45.34%), Query Frame = 2

Query:  236 NKISDENFIYL--KLCGNNKV----LTKMRLTDEHIKGLCGILEEDESVKSLDLRFNRITDKGAEYIANLIKRNHSILEYNLMGNDIEEAGAKFLADAIVKSSTIKTLKMTGNKIGDFGGMQFAQAIQINESLEELDLGECDLKISSVISFATVLLCNTTLKSLNLDRPLLWTQQEETTVHMENMLYINKSLVELHLAKYEMRDFGMERLCDALIINRTLTVLDLSCNRITRDGAKILAKVLKCNTP 958
            N ISD     L   LC N  +    L +  ++ E  + L   L  + ++K LDL  N + D+GA+ IA  +  NHS+   +L  N I+   A+ L  A+  + T+ TL +  N IGD G    A A+++N +L  L L    +      +    L  N TL+ L+L    +     +   +   +   N SL  L+L +  +   G   +  AL  N  L  ++L  N I    A+++++ +K N P
Sbjct:  853 NSISDMGVTVLMRALCSNQTLSSLNLRENSISPEGAQALTQALCRNNTLKHLDLTANLLHDRGAQAIAVAVGENHSLTHLHLQWNFIQAGAARALGQALQLNRTLTTLDLQENAIGDEGASSVAGALKVNTTLIALYLQVASIGSQGAQALGEALTVNRTLEILDLRGNDVGAAGAKALANALKL---NSSLRRLNLQENSLGMDGAIFVASALSENHGLHHINLQGNPIGESAARMISEAIKTNAP 1096

[Close]

BLAST of Leucine rich repeat containing 34 vs. Ensembl Mouse
Match: Nlrc3 (NLR family, CARD domain containing 3 [Source:MGI Symbol;Acc:MGI:2444070])

HSP 1 Score: 110.538 bits (275), Expect = 5.349e-26
Identity = 87/279 (31.18%), Postives = 134/279 (48.03%), Query Frame = 2

Query:  326 KGLCGILEEDESVKSLDLRFNRITDKGAEYIANLIKRNHSILEYNLMGNDIEEAGAKFLADAIVKSSTIKTLKMTGNKIGDFGGMQFAQAIQINESLEELDLGECDLKISSVISFATVLLCNTTLKSLNLDRPLLWTQQEETTVHMENMLYINKSLVELHLAKYEMRDFGMERLCDALIINRTLTVLDLSCNRITRDGAKILAKVLKCNTPLKVLDLGYNRIHNQGIKAIANSLSYCNTNLKCLVITFNEIHDEGLMEITAALELNTTLDKIYIWGNEF 1162
            K L   L+ + ++ SL L+ N I D G   +A  +  N +I    L  N I   GA+ +ADA+ ++ ++K L  + N IGD G +  A+A+++N+ LE LDL    +    V      L  N TL SLNL    +     E    +   L  N +L  L L    + D G + +  A+  N +LT L L  N I    A+ L + L+ N  L  LDL  N I ++G  ++A +L   NT L  L +    I  +G   +  AL +N TL+ + + GN+ 
Sbjct:   44 KALADALKINRTLTSLSLQSNVIKDDGVMCVAEALVSNQTISMLQLQKNLIGLIGAQQMADALKQNRSLKALMFSSNTIGDRGAIALAEALKVNQILENLDLQSNSISDMGVTVLMRALCSNQTLSSLNLRENSI---SPEGAQALTQALCRNNTLKHLDLTANLLHDRGAQAIAVAVGENHSLTHLHLQWNFIQAGAARALGQALQLNRTLTTLDLQENAIGDEGASSVAGAL-KVNTTLIALYLQVASIGSQGAQALGEALTVNRTLEILDLRGNDV 318

HSP 2 Score: 106.301 bits (264), Expect = 1.323e-24
Identity = 92/309 (29.77%), Postives = 145/309 (46.93%), Query Frame = 2

Query:  374 DLRFNRITDKGAEYIANLIKRNHSILEYNLMGNDIEEAGAKFLADAIVKSSTIKTLKMTGNKIGDFGGMQFAQAIQINESLEELDLGECDLKISSVISFATVLLCNTTLKSLNLDRPLLWTQQEETTVHMENMLYINKSLVELHLAKYEMRDFGMERLCDALIINRTLTVLDLSCNRITRDGAKILAKVLKCNTPLKVLDLGYNRIHNQGIKAIA------NSLSY---------------------CNTNLKCLVITFNEIHDEGLMEITAALELNTTLDKIYIWGNEFTSDAIKYFGALMDRFRLME 1219
             L  N+I +KGA+ +A  +  N S++  +L  N I   GAK LADA+  + T+ +L +  N I D G M  A+A+  N+++  L L +  + +      A  L  N +LK+L        T  +   + +   L +N+ L  L L    + D G+  L  AL  N+TL+ L+L  N I+ +GA+ L + L  N  LK LDL  N +H++G +AIA      +SL++                      N  L  L +  N I DEG   +  AL++NTTL  +Y+      S   +  G  +   R +E
Sbjct:    4 SLAENQIGNKGAKALARSLLVNRSLITLDLRSNSIGPPGAKALADALKINRTLTSLSLQSNVIKDDGVMCVAEALVSNQTISMLQLQKNLIGLIGAQQMADALKQNRSLKALMFSSN---TIGDRGAIALAEALKVNQILENLDLQSNSISDMGVTVLMRALCSNQTLSSLNLRENSISPEGAQALTQALCRNNTLKHLDLTANLLHDRGAQAIAVAVGENHSLTHLHLQWNFIQAGAARALGQALQLNRTLTTLDLQENAIGDEGASSVAGALKVNTTLIALYLQVASIGSQGAQALGEALTVNRTLE 309

HSP 3 Score: 74.7146 bits (182), Expect = 4.688e-14
Identity = 69/248 (27.82%), Postives = 114/248 (45.97%), Query Frame = 2

Query:  236 NKISDENFIYL--KLCGNNKVLTKMRL-----TDEHIKGLCGILEEDESVKSLDLRFNRITDKGAEYIANLIKRNHSILEYNLMGNDIEEAGAKFLADAIVKSSTIKTLKMTGNKIGDFGGMQFAQAIQINESLEELDLGECDLKISSVISFATVLLCNTTLKSLNLDRPLLWTQQEETTVHMENMLYINKSLVELHLAKYEMRDFGMERLCDALIINRTLTVLDLSCNRITRDGAKILAKVLKCNTP 958
            N ISD     L   LC +N+ L+ + L     + E  + L   L  + ++K LDL  N + D+GA+ IA  +  NHS+   +L  N I+   A+ L  A+  + T+ TL +  N IGD G    A A+++N +L  L L    +      +    L  N TL+ L+L    +     +   +      +N SL  L+L +  +   G   +  AL  N  L  ++L  N I    A+++++ +K N P
Sbjct:  148 NSISDMGVTVLMRALC-SNQTLSSLNLRENSISPEGAQALTQALCRNNTLKHLDLTANLLHDRGAQAIAVAVGENHSLTHLHLQWNFIQAGAARALGQALQLNRTLTTLDLQENAIGDEGASSVAGALKVNTTLIALYLQVASIGSQGAQALGEALTVNRTLEILDLRGNDVGAAGAKALANAL---KLNSSLRRLNLQENSLGMDGAIFVASALSENHGLHHINLQGNPIGESAARMISEAIKTNAP 391

HSP 4 Score: 74.3294 bits (181), Expect = 6.313e-14
Identity = 74/268 (27.61%), Postives = 125/268 (46.64%), Query Frame = 2

Query:  323 IKGLCGILEEDESVKSLDLRFNRITDKGAEYIANLIKRNHSILEYNLMGNDIEEAGAKFLADAIVKSSTIKTLKMTGNKIGDFGGMQFAQAIQINESLEELDLGECDLKISSVISFATVLLCNTTLKSLNLDRPLLWTQQEETTVHMENMLYINKSLVELHLAKYEMRDFGMERLCDALIINRTLTVLDLSCNRITRDGAKILAKVLKCNTPLKVLDLGYNRIHNQGIKAIANSLSYCNTNLKCLVITFNEIHDEGLMEITAALELNT 1126
            ++ LC     ++++ SL+LR N I+ +GA+ +   + RN+++   +L  N + + GA+ +A A+ ++ ++  L +  N I         QA+Q+N +L  LDL E  +      S A  L  NTT                               L+ L+L    +   G + L +AL +NRTL +LDL  N +   GAK LA  LK N+ L+ L+L  N +   G   +A++LS  N  L  + +  N I +     I+ A++ N 
Sbjct:  159 MRALC----SNQTLSSLNLRENSISPEGAQALTQALCRNNTLKHLDLTANLLHDRGAQAIAVAVGENHSLTHLHLQWNFIQAGAARALGQALQLNRTLTTLDLQENAIGDEGASSVAGALKVNTT-------------------------------LIALYLQVASIGSQGAQALGEALTVNRTLEILDLRGNDVGAAGAKALANALKLNSSLRRLNLQENSLGMDGAIFVASALSE-NHGLHHINLQGNPIGESAARMISEAIKTNA 390

[Close]

BLAST of Leucine rich repeat containing 34 vs. Ensembl Mouse
Match: Nlrc3 (NLR family, CARD domain containing 3 [Source:MGI Symbol;Acc:MGI:2444070])

HSP 1 Score: 98.5969 bits (244), Expect = 2.902e-21
Identity = 82/266 (30.83%), Postives = 127/266 (47.74%), Query Frame = 2

Query:  365 KSLDLRFNRITDKGAEYIANLIK-RNHSILEYNLMGNDIEEAGAKFLADAIVKSSTIKTLKMTGNKIGDFGGMQFAQAIQINESLEELDLGECDLKISSVISFATVLLCNTTLKSLNLDRPLLWTQQEETTVHMENMLYINKSLVELHLAKYEMRDFGMERLCDALIINRTLTVLDLSCNRITRDGAKILAKVLKCNTPLKVLDLGYNRIHNQGIKAIANSLSYCNTNLKCLVITFNEIHDEGLMEITAALELNTTLDKIYIWGNE 1159
            +SL L  N+  D   E + +++  ++  I + +L  N I   GAK LA +++ + ++ TL +  N IG  G    A A++IN +L  L L    +K   V+  A  L+ N T+                      +ML + K+L+ L          G +++ DAL  NR+L  L  S N I   GA  LA+ LK N  L+ LDL  N I + G+  +  +L   N  L  L +  N I DEG   +  AL++NTTL  +Y+ GN+
Sbjct:  661 QSLRLDNNQFQDPVMELLGSVLSGKDCRIRKISLAENQIGNKGAKALARSLLVNRSLITLDLRSNSIGPPGAKALADALKINRTLTSLSLQSNVIKDDGVMCVAEALVSNQTI----------------------SMLQLQKNLIGL---------IGAQQMADALKQNRSLKALMFSSNTIGDRGAIALAEALKVNQILENLDLQSNSISDMGVTVLMRALCS-NQTLSSLNLQENAIGDEGASSVAGALKVNTTLIALYLRGND 894

HSP 2 Score: 85.8853 bits (211), Expect = 3.343e-17
Identity = 80/284 (28.17%), Postives = 133/284 (46.83%), Query Frame = 2

Query:  350 EDESVKSLDLRFNRITDKGAEYIANLIKRNHSILEYNLMGNDIEEAGAKFLADAIVKSSTIKTLKMTGNKIGDFGGMQFAQAIQINESLEELDLGECDLKISSVISFATVLLCNTTLKSLNLDRPLLWTQQEETTVHMENMLYINKSLVELHLAKYEMRDFGMERLCDALIINRTLTVLDLSCNRITRDGAKILAKVLKCNTPLKVLDLGYNRIHNQGIKAIANSLSYCNTNLKCLVITFNEIHDEGLMEITAALELNTTLDKIYIWGNEFTSDAIKYFGALMD 1201
            +D  ++ + L  N+I +KGA+ +A  +  N S++  +L  N I   GAK LADA+  + T+ +L +  N I D G M  A+A+  N+++  L L +                        NL   L+  QQ      M + L  N+SL  L  +   + D G   L +AL +N+ L  LDL  N I+  G  +L + L  N  L  L+L  N I ++G  ++A +L   NT L  L +  N++   G   +  AL+LN++L ++ +  N    D   +  + + 
Sbjct:  685 KDCRIRKISLAENQIGNKGAKALARSLLVNRSLITLDLRSNSIGPPGAKALADALKINRTLTSLSLQSNVIKDDGVMCVAEALVSNQTISMLQLQK------------------------NLIG-LIGAQQ------MADALKQNRSLKALMFSSNTIGDRGAIALAEALKVNQILENLDLQSNSISDMGVTVLMRALCSNQTLSSLNLQENAIGDEGASSVAGALKV-NTTLIALYLRGNDVGAAGAKALANALKLNSSLRRLNLQENSLGMDGAIFVASALS 936

HSP 3 Score: 80.1073 bits (196), Expect = 2.741e-15
Identity = 66/209 (31.58%), Postives = 105/209 (50.24%), Query Frame = 2

Query:  326 KGLCGILEEDESVKSLDLRFNRITDKGAEYIANLIKRNHSILEYNLMGNDIEEAGAKFLADAIVKSSTIKTLKMTGNKIGDFGGMQFAQAIQINESLEELDLGECDLKISSVISFATVLLCNTTLKSLNLDRPLLWTQQEETTVHMENMLYINKSLVELHLAKYEMRDFGMERLCDALIINRTLTVLDLSCNRITRDGAKILAKVLKCN 952
            K L   L+ + ++ SL L+ N I D G   +A  +  N +I    L  N I   GA+ +ADA+ ++ ++K L  + N IGD G +  A+A+++N+ LE LDL    +    V      L  N TL SLNL    +    +E    +   L +N +L+ L+L   ++   G + L +AL +N +L  L+L  N +  DGA  +A  L  N
Sbjct:  733 KALADALKINRTLTSLSLQSNVIKDDGVMCVAEALVSNQTISMLQLQKNLIGLIGAQQMADALKQNRSLKALMFSSNTIGDRGAIALAEALKVNQILENLDLQSNSISDMGVTVLMRALCSNQTLSSLNLQENAIG---DEGASSVAGALKVNTTLIALYLRGNDVGAAGAKALANALKLNSSLRRLNLQENSLGMDGAIFVASALSEN 938

[Close]

BLAST of Leucine rich repeat containing 34 vs. Ensembl Mouse
Match: Nod1 (nucleotide-binding oligomerization domain containing 1 [Source:MGI Symbol;Acc:MGI:1341839])

HSP 1 Score: 84.3445 bits (207), Expect = 1.050e-16
Identity = 74/239 (30.96%), Postives = 106/239 (44.35%), Query Frame = 2

Query:  305 RLTDEHIKGLCGILEEDESVKSLDLRFNRITDKGAEYIANLIKRNHSILEYNLMGNDIEEAGAKFLADAIVKSSTIKTLKMTGNKIGDFGGMQFAQAIQINESLEELDLGECDLKISSVISFATVLLCNTTLKSLNLDRPLLWTQQEETTVHMENMLYINKSLVELHLAKYEMRDFGMERLCDALIINRTLTVLDLSCNRITRDGAKILAKVLKCNTPLKVLDLGYNRIHNQGIKAIAN 1021
            ++TD  +K LC  L + + V  L L  N+ITD GA Y+A ++     +    L  N I   G K +A A+  S++I  + M GN+IGD G   FA+A++ + SL  L L    +      S A  L  NTTL        ++W                        L K E+ D   E   + L +N+TL  L L  NRIT  G   LA+ L+ NT +  + L  N I  +  K   N
Sbjct:  739 QITDTGVKVLCEELTKYKIVTFLGLYNNQITDIGARYVAQILDECRGLKHLKLGKNRITSEGGKCVALAVKNSTSIVDVGMWGNQIGDEGAKAFAEALKDHPSLTTLSLAFNGISPEGGKSLAQALKQNTTLT-------VIW------------------------LTKNELNDESAECFAEMLRVNQTLRHLWLIQNRITAKGTAQLARALQKNTAITEICLNGNLIKPEEAKVFEN 946

HSP 2 Score: 58.5362 bits (140), Expect = 1.466e-8
Identity = 62/239 (25.94%), Postives = 103/239 (43.10%), Query Frame = 2

Query:  377 LRFNRITDKGAEYIANLIKRNHSILEYNLMGNDIEEAGAKFLADAIVKSSTIKTLKMTGNKIGDFGGMQFAQAIQINESLEELDLGECDLKISSVISFATVLLCNTTLKSLNLDRPLLWTQQ--EETTVHMENMLYINKSLVELHLAKYEMRDFGMERLCDALIINRTLTVLDLSCNRITRDGAKILAKVLKCNTPLKVLDLGYNRIHNQGIKAIANSLSYCNTNLKCLVITFNEIHDE 1087
            L  N+ITD G + +   + +   +    L  N I + GA+++A  + +   +K LK+  N+I   GG   A A++ + S+  +D+G                               +W  Q  +E        L  + SL  L LA   +   G + L  AL  N TLTV+ L+ N +  + A+  A++L+ N  L+ L L  NRI  +G   +A +L   NT +  + +  N I  E
Sbjct:  735 LSVNQITDTGVKVLCEELTKYKIVTFLGLYNNQITDIGARYVAQILDECRGLKHLKLGKNRITSEGGKCVALAVKNSTSI--VDVG-------------------------------MWGNQIGDEGAKAFAEALKDHPSLTTLSLAFNGISPEGGKSLAQALKQNTTLTVIWLTKNELNDESAECFAEMLRVNQTLRHLWLIQNRITAKGTAQLARALQK-NTAITEICLNGNLIKPE 939

HSP 3 Score: 58.151 bits (139), Expect = 1.820e-8
Identity = 48/163 (29.45%), Postives = 77/163 (47.24%), Query Frame = 2

Query:  791 LVELHLAKYEMRDFGMERLCDALIINRTLTVLDLSCNRITRDGAKILAKVLKCNTPLKVLDLGYNRIHNQGIKAIA----NSLSYCNT-----------------------NLKCLVITFNEIHDEGLMEITAALELNTTLDKIYIWGNEFTSDAIKYFGALM 1198
            L  + L+  ++ D G++ LC+ L   + +T L L  N+IT  GA+ +A++L     LK L LG NRI ++G K +A    NS S  +                        +L  L + FN I  EG   +  AL+ NTTL  I++  NE   ++ + F  ++
Sbjct:  730 LTVIRLSVNQITDTGVKVLCEELTKYKIVTFLGLYNNQITDIGARYVAQILDECRGLKHLKLGKNRITSEGGKCVALAVKNSTSIVDVGMWGNQIGDEGAKAFAEALKDHPSLTTLSLAFNGISPEGGKSLAQALKQNTTLTVIWLTKNELNDESAECFAEML 892

HSP 4 Score: 55.8398 bits (133), Expect = 1.129e-7
Identity = 35/111 (31.53%), Postives = 59/111 (53.15%), Query Frame = 2

Query:  848 CDALIINRTLTVLDLSC--NRITRDGAKILAKVLKCNTPLKVLDLGYNRIHNQGIKAIANSLSYCNTNLKCLVITFNEIHDEGLMEITAALELNTTLDKIYIWGNEFTSDA 1174
            C AL +  + +++D+    N+I  +GAK  A+ LK +  L  L L +N I  +G K++A +L   NT L  + +T NE++DE        L +N TL  +++  N  T+  
Sbjct:  803 CVALAVKNSTSIVDVGMWGNQIGDEGAKAFAEALKDHPSLTTLSLAFNGISPEGGKSLAQALKQ-NTTLTVIWLTKNELNDESAECFAEMLRVNQTLRHLWLIQNRITAKG 912

[Close]

BLAST of Leucine rich repeat containing 34 vs. UniProt/SwissProt
Match: sp|Q9DAM1|LRC34_MOUSE (Leucine-rich repeat-containing protein 34 OS=Mus musculus OX=10090 GN=Lrrc34 PE=1 SV=1)

HSP 1 Score: 304.679 bits (779), Expect = 3.465e-98
Identity = 165/394 (41.88%), Postives = 241/394 (61.17%), Query Frame = 2

Query:  149 RYVQFCNEKNYEVSDFIRKVFNKEKIRLINKISDENFIYLKLCGNNKVLTKMRLTDEHIKGLCGILEEDESVKSLDLRFNRITDKGAEYIANLIKRNHSILEYNLMGNDIEEAGAKFLADAIVKSSTIKTLKMTGNKIGDFGGMQFAQAIQINESLEELDLGECDLKISSVISFATVLLCNTTLKSLNLDRPLLWTQQEETTVHMENMLYINKSLVELHLAKYEMRDFGMERLCDALIINRTLTVLDLSCNRITRDGAKILAKVLKCNTPLKVLDLGYNRIHNQGIKAIANSLSYCNTNLKCLVITFNEIHDEGLMEITAALELNTTLDKIYIWGNEFTSDAIKYFGALMDRFRLMESKVDVRPYSVDGIHQFALLPHNVDFRRYRYTAPIYGD 1330
            +Y   C+E   + + FI  +  K     I K   E F  + + GNN++ +  R+T E    L   L     +  +D+R+N I D GA Y A L+++  SI   NLM NDI   G + +A A+ K+ T+K L+MTGNKI + GGM FA  +Q+N SLE+LDLG+CDL +  VI+F+TVL  N  +K +NL+RP+L+ +QEE+TVH+ +ML  N  LVELH+ K+ M+++G+++LC+AL +N +L  LD+SCN+ITRDG   LA VLK NT L+VLDL +NRI   G K ++ +L+  N +LK L +  N+I  EGL+ ++ +++ N  L  IYIWGN+F  D    +  L+   RL     DV PY VD      L   +   +R+ Y AP YG+
Sbjct:    7 QYCYLCSENIRKTNPFILNILQKLD-EEIEKRPKEKFT-VNIAGNNRLDSGQRITGEDFWLLSKTLRNQPCISGVDVRYNLIGDVGAFYAAKLLQKQPSITYLNLMFNDIGPEGGELIAKALHKNKTLKYLRMTGNKIENTGGMLFAAMLQMNSSLEKLDLGDCDLGLQCVIAFSTVLTQNQAIKGINLNRPILYGEQEESTVHIGHMLKENHVLVELHMCKHGMKNYGLQQLCNALYLNSSLRYLDVSCNKITRDGMVFLADVLKSNTTLEVLDLSFNRIETAGAKYLSETLTSHNRSLKALSVVSNKIEGEGLVALSQSMKTNLVLSNIYIWGNKFDEDTCVAYSDLIKSGRLKPDNTDVEPYMVD--EHIYLSEVSNGLKRHYYWAPTYGE 396

[Close]

BLAST of Leucine rich repeat containing 34 vs. UniProt/SwissProt
Match: sp|Q4V8D9|LRC34_RAT (Leucine-rich repeat-containing protein 34 OS=Rattus norvegicus OX=10116 GN=Lrrc34 PE=2 SV=1)

HSP 1 Score: 296.59 bits (758), Expect = 5.226e-95
Identity = 159/395 (40.25%), Postives = 241/395 (61.01%), Query Frame = 2

Query:  146 ERYVQFCNEKNYEVSDFIRKVFNKEKIRLINKISDENFIYLKLCGNNKVLTKMRLTDEHIKGLCGILEEDESVKSLDLRFNRITDKGAEYIANLIKRNHSILEYNLMGNDIEEAGAKFLADAIVKSSTIKTLKMTGNKIGDFGGMQFAQAIQINESLEELDLGECDLKISSVISFATVLLCNTTLKSLNLDRPLLWTQQEETTVHMENMLYINKSLVELHLAKYEMRDFGMERLCDALIINRTLTVLDLSCNRITRDGAKILAKVLKCNTPLKVLDLGYNRIHNQGIKAIANSLSYCNTNLKCLVITFNEIHDEGLMEITAALELNTTLDKIYIWGNEFTSDAIKYFGALMDRFRLMESKVDVRPYSVDGIHQFALLPHNVDFRRYRYTAPIYGD 1330
            ++Y   C+E   + +  I  +  K    +  +  ++  I + + GN+++ +  R+T E    L   L     +  +D+R+N I D GA Y A L+++  +I   NLM NDI   G + +A A+ K+ T+K L+MTGNKI + GGM FA  +Q+N SLE+LDLG+CDL + SVI+F+TVL  N  +K +NL+RP+L+ +QEE+TVH+ +M   N  LVELH+ K+ M+++G+++LC+AL  N TL  LD+SCN+ITRDG   LA VLK N+ L+VLDL +NRI N G K ++ +L+  N +LK L +  N+I  EGL+ ++ ++  N  L  IYIWGN+F  D    +  L++  RL     DV PY VD      L   +   +R+ Y  P YG+
Sbjct:    6 DQYSFLCSENIRKTNPLILNILQKLDEEIEKRPKEK--ITVNIAGNSRLDSGQRITSEDFWLLSKALRNHPCIGGVDVRYNLIGDVGAYYAAKLLQKQPNITYLNLMFNDIGPEGGELIAKALQKNKTLKYLRMTGNKIENTGGMLFAAMLQMNSSLEKLDLGDCDLGLQSVIAFSTVLTQNKAIKGINLNRPILYGEQEESTVHIGHMSKQNHVLVELHMCKHGMKNYGIQQLCNALHSNSTLRYLDVSCNKITRDGMVFLADVLKSNSTLEVLDLSFNRIENAGAKYLSETLTSHNRSLKALSVVSNKIEGEGLVALSQSMNTNLVLSNIYIWGNKFDEDTCVAYSNLIESGRLKPENTDVEPYVVD--EHIYLSEVSNGLKRHYYWTPTYGE 396

[Close]

BLAST of Leucine rich repeat containing 34 vs. UniProt/SwissProt
Match: sp|Q8IZ02|LRC34_HUMAN (Leucine-rich repeat-containing protein 34 OS=Homo sapiens OX=9606 GN=LRRC34 PE=2 SV=3)

HSP 1 Score: 285.419 bits (729), Expect = 5.488e-90
Identity = 155/396 (39.14%), Postives = 242/396 (61.11%), Query Frame = 2

Query:  146 ERYVQFCNEKNYEVSDFIRKVFNKEKIRLINKISDENFIYLKLCGNNKVLTKMRLTDEHIKGLCGILEEDESVKSLDLRFNRITDKGAEYIANLIKRNHSILEYNLMGNDIEEAGAKFLADAIVKSSTIKTLKMTGNKIGDFGGMQFAQAIQINESLEELDLGECDLKISSVISFATVLLCNTTLKSLNLDRPLLWTQQEETTVHMENMLYINKSLVELHLAKYEMRDFGMERLCDALIINRTLTVLDLSCNRITRDGAKILAKVLKCNTPLKVLDLGYNRIHNQGIKAIANSLSYCNTNLKCLVITFNEIHDEGLMEITAALELNTTLDKIYIWGNEFTSDAIKYFGALMDRFRLMESKVDVRPYSVDGIHQFALLPHNVDFRRYRYTAPIYGDD 1333
            + Y   C EK+ +++ FI  +  +    +   ++    I L + GNN+++   R+T E    L  IL+    +  LD+ +N + D GA Y A L+++  +++  NLM NDI   G + +A  + K+ T+K L+MTGNKI + GGM FA  +QIN SLE+LDLG+CDL + SVI+FATVL  N  +K++NL+RP+L+++QEE+TVH+  ML  N  LV LH+ K+++++ G+++LCDAL +N +L  LD+SCN+IT DG   LA VLK NT L+V+DL +NRI N G   ++ +L+  N +LK L +  N I  EGL+ ++ +++ N T   IYIWGN+F       +  L+    L     DV P+ VDG    A + + +  +++ Y    YG+ 
Sbjct:   55 KHYSNLCMEKSQKINPFILHILQEVDEEIKKGLAAG--ITLNIAGNNRLVPVERVTGEDFWILSKILKNCLYINGLDVGYNLLCDVGAYYAAKLLQKQLNLIYLNLMFNDIGPEGGELIAKVLHKNRTLKYLRMTGNKIENKGGMFFAAMLQINSSLEKLDLGDCDLGMQSVIAFATVLTQNQAIKAINLNRPILYSEQEESTVHVGRMLKENHCLVALHMCKHDIKNSGIQQLCDALYLNSSLRYLDVSCNKITHDGMVYLADVLKSNTTLEVIDLSFNRIENAGANYLSETLTSHNRSLKALSVVSNNIEGEGLVALSQSMKTNLTFSHIYIWGNKFDEATCIAYSDLIQMGCLKPDNTDVEPFVVDGRVYLAEVSNGL--KKHYYWTSTYGES 446

[Close]

BLAST of Leucine rich repeat containing 34 vs. UniProt/SwissProt
Match: sp|Q5DU56|NLRC3_MOUSE (Protein NLRC3 OS=Mus musculus OX=10090 GN=Nlrc3 PE=1 SV=2)

HSP 1 Score: 113.62 bits (283), Expect = 2.641e-25
Identity = 87/278 (31.29%), Postives = 134/278 (48.20%), Query Frame = 2

Query:  326 KGLCGILEEDESVKSLDLRFNRITDKGAEYIANLIKRNHSILEYNLMGNDIEEAGAKFLADAIVKSSTIKTLKMTGNKIGDFGGMQFAQAIQINESLEELDLGECDLKISSVISFATVLLCNTTLKSLNLDRPLLWTQQEETTVHMENMLYINKSLVELHLAKYEMRDFGMERLCDALIINRTLTVLDLSCNRITRDGAKILAKVLKCNTPLKVLDLGYNRIHNQGIKAIANSLSYCNTNLKCLVITFNEIHDEGLMEITAALELNTTLDKIYIWGNE 1159
            K L   L+ + ++ SL L+ N I D G   +A  +  N +I    L  N I   GA+ +ADA+ ++ ++K L  + N IGD G +  A+A+++N+ LE LDL    +    V      L  N TL SLNL    +     E    +   L  N +L  L L    + D G + +  A+  N +LT L L  N I    A+ L + L+ N  L  LDL  N I ++G  ++A +L   NT L  L +    I  +G   +  AL +N TL+ + + GN+
Sbjct:  711 KALADALKINRTLTSLSLQSNVIKDDGVMCVAEALVSNQTISMLQLQKNLIGLIGAQQMADALKQNRSLKALMFSSNTIGDRGAIALAEALKVNQILENLDLQSNSISDMGVTVLMRALCSNQTLSSLNLRENSI---SPEGAQALTQALCRNNTLKHLDLTANLLHDRGAQAIAVAVGENHSLTHLHLQWNFIQAGAARALGQALQLNRTLTTLDLQENAIGDEGASSVAGALKV-NTTLIALYLQVASIGSQGAQALGEALTVNRTLEILDLRGND 984

HSP 2 Score: 110.538 bits (275), Expect = 2.310e-24
Identity = 93/317 (29.34%), Postives = 150/317 (47.32%), Query Frame = 2

Query:  350 EDESVKSLDLRFNRITDKGAEYIANLIKRNHSILEYNLMGNDIEEAGAKFLADAIVKSSTIKTLKMTGNKIGDFGGMQFAQAIQINESLEELDLGECDLKISSVISFATVLLCNTTLKSLNLDRPLLWTQQEETTVHMENMLYINKSLVELHLAKYEMRDFGMERLCDALIINRTLTVLDLSCNRITRDGAKILAKVLKCNTPLKVLDLGYNRIHNQGIKAIA------NSLSY---------------------CNTNLKCLVITFNEIHDEGLMEITAALELNTTLDKIYIWGNEFTSDAIKYFGALMDRFRLME 1219
            +D  ++ + L  N+I +KGA+ +A  +  N S++  +L  N I   GAK LADA+  + T+ +L +  N I D G M  A+A+  N+++  L L +  + +      A  L  N +LK+L        T  +   + +   L +N+ L  L L    + D G+  L  AL  N+TL+ L+L  N I+ +GA+ L + L  N  LK LDL  N +H++G +AIA      +SL++                      N  L  L +  N I DEG   +  AL++NTTL  +Y+      S   +  G  +   R +E
Sbjct:  663 KDCRIRKISLAENQIGNKGAKALARSLLVNRSLITLDLRSNSIGPPGAKALADALKINRTLTSLSLQSNVIKDDGVMCVAEALVSNQTISMLQLQKNLIGLIGAQQMADALKQNRSLKALMFSSN---TIGDRGAIALAEALKVNQILENLDLQSNSISDMGVTVLMRALCSNQTLSSLNLRENSISPEGAQALTQALCRNNTLKHLDLTANLLHDRGAQAIAVAVGENHSLTHLHLQWNFIQAGAARALGQALQLNRTLTTLDLQENAIGDEGASSVAGALKVNTTLIALYLQVASIGSQGAQALGEALTVNRTLE 976

HSP 3 Score: 77.7962 bits (190), Expect = 8.554e-14
Identity = 75/268 (27.99%), Postives = 126/268 (47.01%), Query Frame = 2

Query:  323 IKGLCGILEEDESVKSLDLRFNRITDKGAEYIANLIKRNHSILEYNLMGNDIEEAGAKFLADAIVKSSTIKTLKMTGNKIGDFGGMQFAQAIQINESLEELDLGECDLKISSVISFATVLLCNTTLKSLNLDRPLLWTQQEETTVHMENMLYINKSLVELHLAKYEMRDFGMERLCDALIINRTLTVLDLSCNRITRDGAKILAKVLKCNTPLKVLDLGYNRIHNQGIKAIANSLSYCNTNLKCLVITFNEIHDEGLMEITAALELNT 1126
            ++ LC     ++++ SL+LR N I+ +GA+ +   + RN+++   +L  N + + GA+ +A A+ ++ ++  L +  N I         QA+Q+N +L  LDL E  +      S A  L  NTTL +L L    + +Q                               G + L +AL +NRTL +LDL  N +   GAK LA  LK N+ L+ L+L  N +   G   +A++LS  N  L  + +  N I +     I+ A++ N 
Sbjct:  826 MRALC----SNQTLSSLNLRENSISPEGAQALTQALCRNNTLKHLDLTANLLHDRGAQAIAVAVGENHSLTHLHLQWNFIQAGAARALGQALQLNRTLTTLDLQENAIGDEGASSVAGALKVNTTLIALYLQVASIGSQ-------------------------------GAQALGEALTVNRTLEILDLRGNDVGAAGAKALANALKLNSSLRRLNLQENSLGMDGAIFVASALSE-NHGLHHINLQGNPIGESAARMISEAIKTNA 1057

HSP 4 Score: 77.411 bits (189), Expect = 1.204e-13
Identity = 68/247 (27.53%), Postives = 112/247 (45.34%), Query Frame = 2

Query:  236 NKISDENFIYL--KLCGNNKV----LTKMRLTDEHIKGLCGILEEDESVKSLDLRFNRITDKGAEYIANLIKRNHSILEYNLMGNDIEEAGAKFLADAIVKSSTIKTLKMTGNKIGDFGGMQFAQAIQINESLEELDLGECDLKISSVISFATVLLCNTTLKSLNLDRPLLWTQQEETTVHMENMLYINKSLVELHLAKYEMRDFGMERLCDALIINRTLTVLDLSCNRITRDGAKILAKVLKCNTP 958
            N ISD     L   LC N  +    L +  ++ E  + L   L  + ++K LDL  N + D+GA+ IA  +  NHS+   +L  N I+   A+ L  A+  + T+ TL +  N IGD G    A A+++N +L  L L    +      +    L  N TL+ L+L    +     +   +   +   N SL  L+L +  +   G   +  AL  N  L  ++L  N I    A+++++ +K N P
Sbjct:  815 NSISDMGVTVLMRALCSNQTLSSLNLRENSISPEGAQALTQALCRNNTLKHLDLTANLLHDRGAQAIAVAVGENHSLTHLHLQWNFIQAGAARALGQALQLNRTLTTLDLQENAIGDEGASSVAGALKVNTTLIALYLQVASIGSQGAQALGEALTVNRTLEILDLRGNDVGAAGAKALANALKL---NSSLRRLNLQENSLGMDGAIFVASALSENHGLHHINLQGNPIGESAARMISEAIKTNAP 1058

[Close]

BLAST of Leucine rich repeat containing 34 vs. UniProt/SwissProt
Match: sp|Q7RTR2|NLRC3_HUMAN (NLR family CARD domain-containing protein 3 OS=Homo sapiens OX=9606 GN=NLRC3 PE=1 SV=2)

HSP 1 Score: 113.235 bits (282), Expect = 3.028e-25
Identity = 90/336 (26.79%), Postives = 151/336 (44.94%), Query Frame = 2

Query:  293 LTKMRLTDEHIKGLCGILEEDESVKSLDLRFNRITDKGAEYIANLIKRNHSILEYNLMGNDIEEAGAKFLADAIVKSSTIKTLKMTGNKIGDFGGMQFAQAIQINESLEELDLGECDLKISSVISFATVLLCNTTLKSLNLDRPLLWTQQEETTVHMENMLYINKSLVELHLAKYEMRDFGMERLCDALIINRTLTVLDLSCNRITRDGAKILAKVLKCNTPLKVLDLGYNRIHNQGIKAIANSL---------------------------SYCNTNLKCLVITFNEIHDEGLMEITAALELNTTLDKIYIWGNEFTSDAIKYFGALMDRFRLME 1219
            L + +++++  K L   L  + S+ SLDLR N I  +GA+ +A+ +K N ++   +L GN + + GA+ +A+A+  + T+  L +  N IG  G  + A A++ N SL+EL              F++  + +   K+L                     L +N+ L  L L    + D G+  L  AL  N+TL  L L  N I+ +GA+ +A  L  N+ LK LDL  N +H+QG +AIA ++                              N +L  L +  N I D+G   +  AL++NT L  +Y+      +   +  G  +   R +E
Sbjct:  673 LAENQISNKGAKALARSLLVNRSLTSLDLRGNSIGPQGAKALADALKINRTLTSLSLQGNTVRDDGARSMAEALASNRTLSMLHLQKNSIGPMGAQRMADALKQNRSLKEL-------------MFSSNSIGDGGAKAL------------------AEALKVNQGLESLDLQSNSISDAGVAALMGALCTNQTLLSLSLRENSISPEGAQAIAHALCANSTLKNLDLTANLLHDQGARAIAVAVRENRTLTSLHLQWNFIQAGAAQALGQALQLNRSLTSLDLQENAIGDDGACAVARALKVNTALTALYLQVASIGASGAQVLGEALAVNRTLE 977

HSP 2 Score: 110.538 bits (275), Expect = 2.771e-24
Identity = 85/273 (31.14%), Postives = 137/273 (50.18%), Query Frame = 2

Query:  308 LTDEHIKGLCGILEEDESVKSLDLRFNRITDKGAEYIANLIKRNHSILEYNLMGNDIEEAGAKFLADAIVKSSTIKTLKMTGNKIGDFGGMQFAQAIQINESLEELDLGECDLKISSVISFATVLLCNTTLKSLNLDRPLLWTQQEETTVHMENMLYINKSLVELHLAKYEMRDFGMERLCDALIINRTLTVLDLSCNRITRDGAKILAKVLKCNTPLKVLDLGYNRIHNQGIKAIANSLSYCNTNLKCLVITFNEIHDEGLMEITAALELNT 1126
            + D   K L   L+ ++ ++SLDL+ N I+D G   +   +  N ++L  +L  N I   GA+ +A A+  +ST+K L +T N + D G    A A++ N +L  L L    ++  +  +    L  N +L SL+L    +    ++    +   L +N +L  L+L    +   G + L +AL +NRTL +LDL  N I   GAK LA  LK N+ L+ L+L  N +   G   IA +LS  N  L+ + +  N I D G   I+ A++ N 
Sbjct:  790 IGDGGAKALAEALKVNQGLESLDLQSNSISDAGVAALMGALCTNQTLLSLSLRENSISPEGAQAIAHALCANSTLKNLDLTANLLHDQGARAIAVAVRENRTLTSLHLQWNFIQAGAAQALGQALQLNRSLTSLDLQENAI---GDDGACAVARALKVNTALTALYLQVASIGASGAQVLGEALAVNRTLEILDLRGNAIGVAGAKALANALKVNSSLRRLNLQENSLGMDGAICIATALSG-NHRLQHINLQGNHIGDSGARMISEAIKTNA 1058

HSP 3 Score: 74.3294 bits (181), Expect = 1.155e-12
Identity = 68/247 (27.53%), Postives = 118/247 (47.77%), Query Frame = 2

Query:  236 NKISDENFIYL--KLCGNNKVLT-KMR---LTDEHIKGLCGILEEDESVKSLDLRFNRITDKGAEYIANLIKRNHSILEYNLMGNDIEEAGAKFLADAIVKSSTIKTLKMTGNKIGDFGGMQFAQAIQINESLEELDLGECDLKISSVISFATVLLCNTTLKSLNLDRPLLWTQQEETTVHMENMLYINKSLVELHLAKYEMRDFGMERLCDALIINRTLTVLDLSCNRITRDGAKILAKVLKCNTP 958
            N ISD     L   LC N  +L+  +R   ++ E  + +   L  + ++K+LDL  N + D+GA  IA  ++ N ++   +L  N I+   A+ L  A+  + ++ +L +  N IGD G    A+A+++N +L  L L    +  S        L  N TL+ L+L    +     +    + N L +N SL  L+L +  +   G   +  AL  N  L  ++L  N I   GA+++++ +K N P
Sbjct:  816 NSISDAGVAALMGALCTNQTLLSLSLRENSISPEGAQAIAHALCANSTLKNLDLTANLLHDQGARAIAVAVRENRTLTSLHLQWNFIQAGAAQALGQALQLNRSLTSLDLQENAIGDDGACAVARALKVNTALTALYLQVASIGASGAQVLGEALAVNRTLEILDLRGNAIGVAGAKA---LANALKVNSSLRRLNLQENSLGMDGAICIATALSGNHRLQHINLQGNHIGDSGARMISEAIKTNAP 1059

[Close]

BLAST of Leucine rich repeat containing 34 vs. TrEMBL
Match: A0A267GWA9 (Uncharacterized protein (Fragment) OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig006139g1 PE=4 SV=1)

HSP 1 Score: 382.874 bits (982), Expect = 3.303e-126
Identity = 201/407 (49.39%), Postives = 268/407 (65.85%), Query Frame = 2

Query:  140 TCERYVQFCNEKNYEVSDFIRKVFNKEKIRLINKISDENFIYLKLCGNNKV--LTKMRLTDEHIKGLCGILEEDESVKSLDLRFNRITDKGAEYIANLIKRNHSILEYNLMGNDIEEAGAKFLADAIVKSSTIKTLKMTGNKIGDFGGMQFAQAIQINESLEELDLGECDLKISSVISFATVLLCNTTLKSLNLDRPLLWTQQEETTVHMENMLYINKSLVELHLAKYEMRDFGMERLCDALIINRTLTVLDLSCNRITRDGAKILAKVLKCNTPLKVLDLGYNRIHNQGIKAIANSLSYCNTNLKCLVITFNEIHDEGLMEITAALELNTTLDKIYIWGNEFT--SDAIKYFGALMDRFRLMESKVDVRPYSVDGIHQFALLPHNVDFRRYRYTAPIYGDDIPENR 1348
            T   Y++ C       + F+  V  + K       + E F  LKLC NNK+     +RL D     LC  L        +DLR+N I D GAE IA+++  N +I   NLM N++ EAGAK +A ++  + T+  L + GNKI D GGM FA+A+Q+N +LE LDLG+CDLKI++VI+ +TVL  N +L+ +N++RPLLWTQQEETTVHM  ML  N+SL ELHLAKYEMRDFG  R+ D L+ NR LTVLDLSCNRITRDGAK+LA VL  +TPL++LDL YNR+   G K IA++L   NTNL+CLVI FNEI  +GL+ +  +L+ NT+L++++IWGN+ T  S A  Y   L    RL E   DVR YSVD     + +  +VD+R YR+TAP+YGD +P++R
Sbjct:   11 TVVSYIENCKASQLSANAFVLDVLQRLKDESAFDDNVETF-DLKLCANNKLSNTRNIRLVDADAAVLCRTLRSSTIFVCVDLRYNSIGDSGAEAIADMLSSNKTITMLNLMCNNVGEAGAKAIAKSLHTNQTLLELNLAGNKINDAGGMLFAEALQVNATLEFLDLGDCDLKINAVIALSTVLKYNDSLRGINVNRPLLWTQQEETTVHMGEMLAQNRSLRELHLAKYEMRDFGANRIADGLVANRALTVLDLSCNRITRDGAKVLANVLCRDTPLQLLDLSYNRLECDGAKCIASALIGANTNLRCLVIKFNEIKSDGLVAVADSLKYNTSLERLFIWGNDLTDASCAAAYAELLGSSGRLREDDTDVRAYSVDDRWCLSQVNRDVDYRLYRFTAPVYGDQVPQDR 416

[Close]

BLAST of Leucine rich repeat containing 34 vs. TrEMBL
Match: A0A267H3H2 (Uncharacterized protein (Fragment) OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig007357g1 PE=4 SV=1)

HSP 1 Score: 382.874 bits (982), Expect = 3.642e-126
Identity = 201/407 (49.39%), Postives = 267/407 (65.60%), Query Frame = 2

Query:  140 TCERYVQFCNEKNYEVSDFIRKVFNKEKIRLINKISDENFIYLKLCGNNKV--LTKMRLTDEHIKGLCGILEEDESVKSLDLRFNRITDKGAEYIANLIKRNHSILEYNLMGNDIEEAGAKFLADAIVKSSTIKTLKMTGNKIGDFGGMQFAQAIQINESLEELDLGECDLKISSVISFATVLLCNTTLKSLNLDRPLLWTQQEETTVHMENMLYINKSLVELHLAKYEMRDFGMERLCDALIINRTLTVLDLSCNRITRDGAKILAKVLKCNTPLKVLDLGYNRIHNQGIKAIANSLSYCNTNLKCLVITFNEIHDEGLMEITAALELNTTLDKIYIWGNEFT--SDAIKYFGALMDRFRLMESKVDVRPYSVDGIHQFALLPHNVDFRRYRYTAPIYGDDIPENR 1348
            T   Y++ C       + F+  V  + K         E F  LKLC NNK+     +RL D     LC  L        +DLR+N I D GAE IA+++  N +I   NLM N++ EAGAK +A ++  + T+  L + GNKI D GGM FA+A+Q+N +LE LDLG+CDLKI++VI+ +TVL  N +L+ +N++RPLLWTQQEETTVHM  ML  N+SL ELHLAKYEMRDFG  R+ D L+ NR LTVLDLSCNRITRDGAK+LA VL  +TPL++LDL YNR+   G K IA++L   NTNL+CLVI FNEI  +GL+ +  +L+ NT+L++++IWGN+ T  S A  Y   L    RL E   DVR YSVD     + +  +VD+R YR+TAP+YGD +P++R
Sbjct:   11 TVVSYIENCKASQLSANAFVLDVLQRLKDESAFDDDVETF-DLKLCANNKLSNTRNIRLVDADAAVLCRTLRSSTIFVCVDLRYNSIGDSGAEAIADMLSSNKTITMLNLMCNNVGEAGAKAIAKSLHTNQTLLELNLAGNKINDAGGMLFAEALQVNATLEFLDLGDCDLKINAVIALSTVLKYNDSLRGINVNRPLLWTQQEETTVHMGEMLAQNRSLRELHLAKYEMRDFGANRIADGLVANRALTVLDLSCNRITRDGAKVLANVLCRDTPLQLLDLSYNRLECDGAKCIASALIGANTNLRCLVIKFNEIKSDGLVAVADSLKYNTSLERLFIWGNDLTDASCAAAYAELLGSSGRLREDDTDVRAYSVDDRWCLSQVNRDVDYRLYRFTAPVYGDQVPQDR 416

[Close]

BLAST of Leucine rich repeat containing 34 vs. TrEMBL
Match: A0A267F161 (Uncharacterized protein (Fragment) OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig008765g1 PE=4 SV=1)

HSP 1 Score: 382.489 bits (981), Expect = 5.937e-126
Identity = 201/407 (49.39%), Postives = 267/407 (65.60%), Query Frame = 2

Query:  140 TCERYVQFCNEKNYEVSDFIRKVFNKEKIRLINKISDENFIYLKLCGNNKV--LTKMRLTDEHIKGLCGILEEDESVKSLDLRFNRITDKGAEYIANLIKRNHSILEYNLMGNDIEEAGAKFLADAIVKSSTIKTLKMTGNKIGDFGGMQFAQAIQINESLEELDLGECDLKISSVISFATVLLCNTTLKSLNLDRPLLWTQQEETTVHMENMLYINKSLVELHLAKYEMRDFGMERLCDALIINRTLTVLDLSCNRITRDGAKILAKVLKCNTPLKVLDLGYNRIHNQGIKAIANSLSYCNTNLKCLVITFNEIHDEGLMEITAALELNTTLDKIYIWGNEFT--SDAIKYFGALMDRFRLMESKVDVRPYSVDGIHQFALLPHNVDFRRYRYTAPIYGDDIPENR 1348
            T   Y++ C       + F+  V  + K         E F  LKLC NNK+     +RL D     LC  L        +DLR+N I D GAE IA+++  N +I   NLM N++ EAGAK +A ++  + T+  L + GNKI D GGM FA+A+Q+N +LE LDLG+CDLKI++VI+ +TVL  N +L+ +N++RPLLWTQQEETTVHM  ML  N+SL ELHLAKYEMRDFG  R+ D L+ NR LTVLDLSCNRITRDGAK+LA VL  +TPL++LDL YNR+   G K IA++L   NTNL+CLVI FNEI  +GL+ +  +L+ NT+L++++IWGN+ T  S A  Y   L    RL E   DVR YSVD     + +  +VD+R YR+TAP+YGD +P++R
Sbjct:   11 TVVSYIENCKASQLSANAFVLDVLQRLKDESAFDDDVETF-DLKLCANNKLSNTRDIRLVDADAAVLCRTLRSSTIFVCVDLRYNSIGDSGAEAIADMLSSNKTITMLNLMCNNVGEAGAKAIAKSLHTNQTLLELNLAGNKINDAGGMLFAEALQVNATLEFLDLGDCDLKINAVIALSTVLKYNDSLRGINVNRPLLWTQQEETTVHMGEMLAQNRSLRELHLAKYEMRDFGANRIADGLVANRALTVLDLSCNRITRDGAKVLANVLCRDTPLQLLDLSYNRLECDGAKCIASALIGANTNLRCLVIKFNEIKSDGLVAVADSLKYNTSLERLFIWGNDLTDASCAAAYAELLGSSGRLREDDTDVRAYSVDDRWCLSQVNRDVDYRLYRFTAPVYGDQVPQDR 416

[Close]

BLAST of Leucine rich repeat containing 34 vs. TrEMBL
Match: A0A1I8I0P8 (Uncharacterized protein OS=Macrostomum lignano OX=282301 PE=4 SV=1)

HSP 1 Score: 382.104 bits (980), Expect = 6.468e-126
Identity = 201/407 (49.39%), Postives = 267/407 (65.60%), Query Frame = 2

Query:  140 TCERYVQFCNEKNYEVSDFIRKVFNKEKIRLINKISDENFIYLKLCGNNKV--LTKMRLTDEHIKGLCGILEEDESVKSLDLRFNRITDKGAEYIANLIKRNHSILEYNLMGNDIEEAGAKFLADAIVKSSTIKTLKMTGNKIGDFGGMQFAQAIQINESLEELDLGECDLKISSVISFATVLLCNTTLKSLNLDRPLLWTQQEETTVHMENMLYINKSLVELHLAKYEMRDFGMERLCDALIINRTLTVLDLSCNRITRDGAKILAKVLKCNTPLKVLDLGYNRIHNQGIKAIANSLSYCNTNLKCLVITFNEIHDEGLMEITAALELNTTLDKIYIWGNEFT--SDAIKYFGALMDRFRLMESKVDVRPYSVDGIHQFALLPHNVDFRRYRYTAPIYGDDIPENR 1348
            T   Y++ C       + F+  V  + K         E F  LKLC NNK+     +RL D     LC  L        +DLR+N I D GAE IA+++  N +I   NLM N++ EAGAK +A ++  + T+  L + GNKI D GGM FA+A+Q+N +LE LDLG+CDLKI++VI+ +TVL  N +L+ +N++RPLLWTQQEETTVHM  ML  N+SL ELHLAKYEMRDFG  R+ D L+ NR LTVLDLSCNRITRDGAK+LA VL  +TPL++LDL YNR+   G K IA++L   NTNL+CLVI FNEI  +GL+ +  +L+ NT+L++++IWGN+ T  S A  Y   L    RL E   DVR YSVD     + +  +VD+R YR+TAP+YGD +P++R
Sbjct:    8 TVVSYIENCKASQLSANAFVLDVLQRLKDESAFDDDVETF-DLKLCANNKLSNTRNIRLVDADAAVLCRTLRSSTIFVCVDLRYNSIGDSGAEAIADMLSSNKTITMLNLMCNNVGEAGAKAIAKSLHTNQTLLELNLAGNKINDAGGMLFAEALQVNATLEFLDLGDCDLKINAVIALSTVLKYNDSLRGINVNRPLLWTQQEETTVHMGEMLAQNRSLRELHLAKYEMRDFGANRIADGLVANRALTVLDLSCNRITRDGAKVLANVLCRDTPLQLLDLSYNRLECDGAKCIASALIGANTNLRCLVIKFNEIKSDGLVAVADSLKYNTSLERLFIWGNDLTDASCAAAYAELLGSSGRLREDDTDVRAYSVDDRWCLSQVNRDVDYRLYRFTAPVYGDQVPQDR 413

[Close]

BLAST of Leucine rich repeat containing 34 vs. TrEMBL
Match: W5MJT0 (Leucine rich repeat containing 34 OS=Lepisosteus oculatus OX=7918 PE=4 SV=1)

HSP 1 Score: 364.385 bits (934), Expect = 8.937e-119
Identity = 193/396 (48.74%), Postives = 257/396 (64.90%), Query Frame = 2

Query:  146 ERYVQFCNEKNYEVSDFIRKVFNKEKIRLINKISDENFIYLKLCGNNKVLTKMRLTDEHIKGLCGILEEDESVKSLDLRFNRITDKGAEYIANLIKRNHSILEYNLMGNDIEEAGAKFLADAIVKSSTIKTLKMTGNKIGDFGGMQFAQAIQINESLEELDLGECDLKISSVISFATVLLCNTTLKSLNLDRPLLWTQQEETTVHMENMLYINKSLVELHLAKYEMRDFGMERLCDALIINRTLTVLDLSCNRITRDGAKILAKVLKCNTPLKVLDLGYNRIHNQGIKAIANSLSYCNTNLKCLVITFNEIHDEGLMEITAALELNTTLDKIYIWGNEFTSDAIKYFGALMDRFRLMESKVDVRPYSVDGIHQFALLPHNVDFRRYRYTAPIYGDD 1333
            + Y   C+E     + +I  V +    R ++++S E  + +KL GNN++L   RL+D  +  L   L ++ SV+ LDLR+N ITD+GA ++  L++ N S+   NLMGNDIE +GA+F+A A+ ++ T+KTL+MTGNKIGD GGM FA  +QIN SLEELDLG+CDL   S+I+FA VL  N     +NL RPLL++QQEETTVHM  ML +N+ L ELHL K+EM+DFG+ERLCDAL  N TL  LDL CN ITRDGAK LA++LK NT L++LDL  NRI + G   ++ +L+  N  LK L I  N I   GL+ +  AL++NTTL  IYIWGN   + A   F  L++  RL E   DV PY V+G    + L H    RR+ Y  P YG D
Sbjct:   22 DSYSAVCSESELPTNPYILHVLHDTDER-VSRLSPEEGVEIKLTGNNRLLPVQRLSDTDVLALSKALADNVSVRGLDLRYNSITDEGAAHLGVLLQENVSLRCLNLMGNDIEVSGAEFIAKALHRNETLKTLQMTGNKIGDKGGMHFAAMLQINSSLEELDLGDCDLDTQSLIAFAIVLNHNKNAHVINLSRPLLFSQQEETTVHMARMLKVNRHLRELHLGKHEMKDFGVERLCDALSFNSTLRYLDLRCNSITRDGAKCLAELLKQNTGLEILDLASNRIEDDGAVYLSEALAMYNNTLKALSIPSNNIGARGLVSLAKALKVNTTLSHIYIWGNILEAPACLAFSKLIESGRLSEEDTDVSPYEVEGRVCLSELFHG--LRRHYYWTPSYGQD 414

[Close]

BLAST of Leucine rich repeat containing 34 vs. Ensembl Cavefish
Match: lrrc34 (leucine rich repeat containing 34 [Source:NCBI gene;Acc:103033083])

HSP 1 Score: 289.271 bits (739), Expect = 7.147e-93
Identity = 169/394 (42.89%), Postives = 243/394 (61.68%), Query Frame = 2

Query:  152 YVQFCNEKNYEVSDFIRKVFNKEKIRLINKISDENFIYLKLCGNNKVLTKMRLTDEHIKGLCGILEEDESVKSLDLRFNRITDKGAEYIANLIKRNHSILEYNLMGNDIEEAGAKFLADAIVKSSTIKTLKMTGNKIGDFGGMQFAQAIQINESLEELDLGECDLKISSVISFATVLLCNTTLKSLNLDRPLLWTQQEETTVHMENMLYINKSLVELHLAKYEMRDFGMERLCDALIINRTLTVLDLSCNRITRDGAKILAKVLKCNTPLKVLDLGYNRIHNQGIKAIANSLSYCNTNLKCLVITFNEIHDEGLMEITAALELNTTLDKIYIWGNEFTSDAIKYFGALMDRFRLMESKVDVRPYSVDGIHQFALLPHNVDFRRYRYTAPIYGDD 1333
            Y+  C++   + +  + +V  +         S  + I L+L GN +     RL+D  +  L   L  + SVK++DLR+NRI D+GA ++A+L++ N ++   +LM NDIE  GA+ LA ++ +++T+K L+MTGNKIG+ G M FA  +QIN SLE+LD+ +CDL   S+I+FA VL  N  ++S+N+ RPLL++ QEETT+HM  ML +N++L ELH+ K+ M D G+ERLC+AL+IN TL  LDL CNRI+RDGAK LA VLK N  L++LDL  NRI + G   ++ ++   +  L+ L IT N I   GL+ +T A+  N  L  IYIWGN         F  L+   RL++   DV PY VDG    A + H    RR+ Y  P YG D
Sbjct:   28 YLSVCDDLQLDPNPCVSRVLTEAH-------SCSSGISLRLRGNERRSGVNRLSDTDLLLLSKTLRNEGSVKAVDLRYNRIADEGAGHLADLLQENEALESLDLMCNDIEVQGAERLAKSLHQNATLKRLRMTGNKIGNKGAMHFASMLQINTSLEDLDVSDCDLGTQSLIAFAIVLNNNRNIRSINISRPLLFSLQEETTIHMARMLAVNQTLRELHMGKHGMTDSGVERLCEALMINCTLRYLDLRCNRISRDGAKCLAGVLKKNNTLEILDLSSNRIEDDGAVYLSKAIMQPHCKLRALSITSNNIATTGLVSLTKAMVSNPQLTHIYIWGNRLEEPLCVAFSQLIASGRLLKEHTDVFPYEVDGHFYLAEVFHG--LRRHYYWTPSYGQD 412

[Close]

BLAST of Leucine rich repeat containing 34 vs. Ensembl Cavefish
Match: nlrc3 (NLR family CARD domain containing 3 [Source:NCBI gene;Acc:103024894])

HSP 1 Score: 114.39 bits (285), Expect = 1.465e-26
Identity = 84/268 (31.34%), Postives = 142/268 (52.99%), Query Frame = 2

Query:  350 EDESVKSLDLRFNRITDKGAEYIANLIKRNHSILEYNLMGNDIEEAGAKFLADAIVKSSTIKTLKMTGNKIGDFGGMQFAQAIQINESLEELDLGECDLKISSVISFATVLLCNTTLKSLNLDRPLLWTQQEETTVHMENMLYINKSLVELHLAKYEMRDFGMERLCDALIINRTLTVLDLSCNRITRDGAKILAKVLKCNTPLKVLDLGYNRIHNQGIKAIANSLSYCNTNLKCLVITFNEIHDEGLMEITAALELNTTLDKIYIWG 1153
            +D  ++ L L  + I+ KG + ++  +  N ++   +L GN+I   GAK LA+A+  +  I ++ +  N I D G    A+ +Q N  L  L++ +  +    V   A  L  N  L+ LN+    L    +  TV +   L +N +L  L L    + D GM+ L  AL  NR LT L+L  N I  +GAK +A+ L+ N+ L+ LDL +N +     KA+A SL + N++++ L +  N + DEG++ +  AL+ N++L  +Y+ G
Sbjct:  481 KDCHIQFLSLADSSISSKGIKPLSRALLVNRTLTILDLHGNNIGTKGAKTLAEALRMNQIIVSINLQSNSIEDEGARALAEVLQSNRKLTSLNVQKNGIGPDGVKRIAESLKKNQILQDLNVSSNHL---GDLGTVALAQALVVNHTLCTLSLQSNSVSDKGMKALTLALRSNRGLTTLNLRENSIGVEGAKAIARALQENSTLRELDLQWNFMKIGAAKALAQSL-HSNSSIQLLDLQENTLGDEGVVALAGALKANSSLAVLYLQG 744

HSP 2 Score: 93.5893 bits (231), Expect = 7.545e-20
Identity = 88/299 (29.43%), Postives = 146/299 (48.83%), Query Frame = 2

Query:  236 NKISDENFIYL-KLCGNNKVLTKMR-----LTDEHIKGLCGILEEDESVKSLDLRFNRITDKGAEYIANLIKRNHSILEYNLMGNDIEEAGAKFLADAIVKSSTIKTLKMTGNKIGDFGGMQFAQAIQINESLEELDLGECDLKISSVISFATVLLCNTTLKSLNLDRPLLWTQQEETTVHMENMLYINKSLVELHLAKYEMRDFGMERLCDALIINRTLTVLDLSCNRITRDGAKILAKVLKCNTPLKVLDLGYNRIHNQGIKAIANSLSYCNTNLKCLVITFNEIHDEGLMEITAAL 1114
            N I DE    L ++  +N+ LT +      +  + +K +   L++++ ++ L++  N + D G   +A  +  NH++   +L  N + + G K L  A+  +  + TL +  N IG  G    A+A+Q N +L ELDL    +KI +  + A  L  N++++ L+L    L    +E  V +   L  N SL  L+L        G E L +AL++N+TL  LDL  N I   GAK L+  LK N  L+ L+L  N +   G   IA +L   N  L  + +  N I + G   ++ A+
Sbjct:  549 NSIEDEGARALAEVLQSNRKLTSLNVQKNGIGPDGVKRIAESLKKNQILQDLNVSSNHLGDLGTVALAQALVVNHTLCTLSLQSNSVSDKGMKALTLALRSNRGLTTLNLRENSIGVEGAKAIARALQENSTLRELDLQWNFMKIGAAKALAQSLHSNSSIQLLDLQENTL---GDEGVVALAGALKANSSLAVLYLQGVSAGKAGAEALAEALMVNQTLCTLDLRGNSIGMGGAKALSSALKTNRSLRSLNLQENSLGMDGAIFIATAL-RGNHQLTYINLQGNGIGESGAKVVSDAI 843

HSP 3 Score: 65.0846 bits (157), Expect = 1.030e-10
Identity = 63/253 (24.90%), Postives = 117/253 (46.25%), Query Frame = 2

Query:  236 NKISDENFIYLKLC-GNNKVLTKMRLTDEHI-----KGLCGILEEDESVKSLDLRFNRITDKGAEYIANLIKRNHSILEYNLMGNDIEEAGAKFLADAIVKSSTIKTLKMTGNKIGDFGGMQFAQAIQINESLEELDLGECDLKISSVISFATVLLCNTTLKSLNLDRPLLWTQQEETTVHMENMLYINKSLVELHLAKYEMRDFGMERLCDALIINRTLTVLDLSCNRITRDGAKILAKVLKCNTPLKVLDL 976
            N +SD+    L L   +N+ LT + L +  I     K +   L+E+ +++ LDL++N +    A+ +A  +  N SI   +L  N + + G   LA A+  +S++  L + G   G  G    A+A+ +N++L  LDL    + +    + ++ L  N +L+SLNL         +E ++ M+  ++I                        AL  N  LT ++L  N I   GAK+++  ++ +    V+D+
Sbjct:  633 NSVSDKGMKALTLALRSNRGLTTLNLRENSIGVEGAKAIARALQENSTLRELDLQWNFMKIGAAKALAQSLHSNSSIQLLDLQENTLGDEGVVALAGALKANSSLAVLYLQGVSAGKAGAEALAEALMVNQTLCTLDLRGNSIGMGGAKALSSALKTNRSLRSLNL---------QENSLGMDGAIFI----------------------ATALRGNHQLTYINLQGNGIGESGAKVVSDAIRTDAAECVVDI 854

HSP 4 Score: 64.6994 bits (156), Expect = 1.205e-10
Identity = 42/121 (34.71%), Postives = 64/121 (52.89%), Query Frame = 2

Query:  800 LHLAKYEMRDFGMERLCDALIINRTLTVLDLSCNRITRDGAKILAKVLKCNTPLKVLDLGYNRIHNQGIKAIANSLSYCNTNLKCLVITFNEIHDEGLMEITAALELNTTLDKIYIWGNEF 1162
            L LA   +   G++ L  AL++NRTLT+LDL  N I   GAK LA+ L+ N  +  ++L  N I ++G +A+A  L   N  L  L +  N I  +G+  I  +L+ N  L  + +  N  
Sbjct:  488 LSLADSSISSKGIKPLSRALLVNRTLTILDLHGNNIGTKGAKTLAEALRMNQIIVSINLQSNSIEDEGARALAEVL-QSNRKLTSLNVQKNGIGPDGVKRIAESLKKNQILQDLNVSSNHL 607

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BLAST of Leucine rich repeat containing 34 vs. Ensembl Cavefish
Match: nlrc3 (NLR family CARD domain containing 3 [Source:NCBI gene;Acc:103024894])

HSP 1 Score: 110.153 bits (274), Expect = 3.228e-25
Identity = 82/287 (28.57%), Postives = 150/287 (52.26%), Query Frame = 2

Query:  293 LTKMRLTDEHIKGLCGILEEDESVKSLDLRFNRITDKGAEYIANLIKRNHSILEYNLMGNDIEEAGAKFLADAIVKSSTIKTLKMTGNKIGDFGGMQFAQAIQINESLEELDLGECDLKISSVISFATVLLCNTTLKSLNLDRPLLWTQQEETTVHMENMLYINKSLVELHLAKYEMRDFGMERLCDALIINRTLTVLDLSCNRITRDGAKILAKVLKCNTPLKVLDLGYNRIHNQGIKAIANSLSYCNTNLKCLVITFNEIHDEGLMEITAALELNTTLDKIYIWG 1153
            L    ++ + IK L   L  + ++  LDL  N I  KGA+ +A  ++ N  I+  NL  N IE+ GA+ LA+ +  +  + +L +  N IG  G  + A++++ N+ L++L++    L     ++ A  L+ N TL +L+L      +  ++    +   L  N+ L  L+L +  +   G + +  AL  N TL  LDL+ N +  +G   +A  +K N  L+ L L +N +     KA+A SL + N++++ L +  N + DEG++ +  AL+ N++L  +Y+ G
Sbjct:  490 LADSSISSKGIKPLSRALLVNRTLTILDLHGNNIGTKGAKTLAEALRMNQIIVSINLQSNSIEDEGARALAEVLQSNRKLTSLNVQKNGIGPDGVKRIAESLKKNQILQDLNVSSNHLGDLGTVALAQALVVNHTLCTLSLQSN---SVSDKGMKALTLALRSNRGLTTLNLRENSIGVEGAKAIARALQENSTLRELDLTANLLHDEGVTAIAGSVKVNRALRSLHLQWNFMKIGAAKALAQSL-HSNSSIQLLDLQENTLGDEGVVALAGALKANSSLAVLYLQG 772

HSP 2 Score: 99.7525 bits (247), Expect = 7.715e-22
Identity = 76/274 (27.74%), Postives = 133/274 (48.54%), Query Frame = 2

Query:  371 LDLRFNRITDKGAEYIANLIKRNHSILEY-NLMGNDIEEAGAKFLADAIVKSSTIKTLKMTGNKIGDFGGMQFAQAIQINESLEELDLGECDLKISSVISFATVLLCNTTLKSLNLDRPLLWTQQEETTVHMENMLYINKSLVELHLAKYEMRDFGMERLCDALIINRTLTVLDLSCNRITRDGAKILAKVLKCNTPLKVLDLGYNRIHNQGIKAIANSLSYCNTNLKCLVITFNEIHDEGLMEITAALELNTTLDKIYIWGNEFTSDAIKYFG 1189
            L +  N   D   E + +L+      +++ +L  + I   G K L+ A++ + T+  L + GN IG  G    A+A+++N+ +  ++L    ++     + A VL  N  L SLN+ +  +     +    +   L  N+ L +L+++   + D G   L  AL++N TL  L L  N ++  G K L   L+ N  L  L+L  N I  +G KAIA +L   N+ L+ L +T N +HDEG+  I  ++++N  L  +++  N     A K   
Sbjct:  459 LRMENNGFKDDAMELLGSLLSAKDCHIQFLSLADSSISSKGIKPLSRALLVNRTLTILDLHGNNIGTKGAKTLAEALRMNQIIVSINLQSNSIEDEGARALAEVLQSNRKLTSLNVQKNGI---GPDGVKRIAESLKKNQILQDLNVSSNHLGDLGTVALAQALVVNHTLCTLSLQSNSVSDKGMKALTLALRSNRGLTTLNLRENSIGVEGAKAIARALQE-NSTLRELDLTANLLHDEGVTAIAGSVKVNRALRSLHLQWNFMKIGAAKALA 728

HSP 3 Score: 95.5153 bits (236), Expect = 2.125e-20
Identity = 83/282 (29.43%), Postives = 140/282 (49.65%), Query Frame = 2

Query:  284 NKVLTKMRLTDEHIK-----GLCGILEEDESVKSLDLRFNRITDKGAEYIANLIKRNHSILEYNLMGNDIEEAGAKFLADAIVKSSTIKTLKMTGNKIGDFGGMQFAQAIQINESLEELDLGECDLKISSVISFATVLLCNTTLKSLNLDRPLLWTQQEETTVHMENMLYINKSLVELHLAKYEMRDFGMERLCDALIINRTLTVLDLSCNRITRDGAKILAKVLKCNTPLKVLDLGYNRIHNQGIKAIANSLSYCNTNLKCLVITFNEIHDEGLMEITAAL 1114
            N++L  + ++  H+       L   L  + ++ +L L+ N ++DKG + +   ++ N  +   NL  N I   GAK +A A+ ++ST++ L +T N + D G    A ++++N +L  L L    +KI +  + A  L  N++++ L+L    L    +E  V +   L  N SL  L+L        G E L +AL++N+TL  LDL  N I   GAK L+  LK N  L+ L+L  N +   G   IA +L   N  L  + +  N I + G   ++ A+
Sbjct:  594 NQILQDLNVSSNHLGDLGTVALAQALVVNHTLCTLSLQSNSVSDKGMKALTLALRSNRGLTTLNLRENSIGVEGAKAIARALQENSTLRELDLTANLLHDEGVTAIAGSVKVNRALRSLHLQWNFMKIGAAKALAQSLHSNSSIQLLDLQENTL---GDEGVVALAGALKANSSLAVLYLQGVSAGKAGAEALAEALMVNQTLCTLDLRGNSIGMGGAKALSSALKTNRSLRSLNLQENSLGMDGAIFIATAL-RGNHQLTYINLQGNGIGESGAKVVSDAI 871

HSP 4 Score: 75.8702 bits (185), Expect = 3.984e-14
Identity = 70/253 (27.67%), Postives = 124/253 (49.01%), Query Frame = 2

Query:  236 NKISDENFIYLKLC-GNNKVLTKMRLTDEHI-----KGLCGILEEDESVKSLDLRFNRITDKGAEYIANLIKRNHSILEYNLMGNDIEEAGAKFLADAIVKSSTIKTLKMTGNKIGDFGGMQFAQAIQINESLEELDLGECDLKISSVISFATVLLCNTTLKSLNLDRPLLWTQQEETTVHMENMLYINKSLVELHLAKYEMRDFGMERLCDALIINRTLTVLDLSCNRITRDGAKILAKVLKCNTPLKVLDL 976
            N +SD+    L L   +N+ LT + L +  I     K +   L+E+ +++ LDL  N + D+G   IA  +K N ++   +L  N ++   AK LA ++  +S+I+ L +  N +GD G +  A A++ N SL  L L       +   + A  L+ N TL +L+L    +     +    + + L  N+SL  L+L +  +   G   +  AL  N  LT ++L  N I   GAK+++  ++ +    V+D+
Sbjct:  633 NSVSDKGMKALTLALRSNRGLTTLNLRENSIGVEGAKAIARALQENSTLRELDLTANLLHDEGVTAIAGSVKVNRALRSLHLQWNFMKIGAAKALAQSLHSNSSIQLLDLQENTLGDEGVVALAGALKANSSLAVLYLQGVSAGKAGAEALAEALMVNQTLCTLDLRGNSIGMGGAKA---LSSALKTNRSLRSLNLQENSLGMDGAIFIATALRGNHQLTYINLQGNGIGESGAKVVSDAIRTDAAECVVDI 882

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BLAST of Leucine rich repeat containing 34 vs. Ensembl Cavefish
Match: lrrc74a (leucine rich repeat containing 74A [Source:NCBI gene;Acc:103039030])

HSP 1 Score: 96.6709 bits (239), Expect = 6.228e-21
Identity = 73/227 (32.16%), Postives = 113/227 (49.78%), Query Frame = 2

Query:  296 TKMRLTDEHIKG-----LCGILEEDESVKSLDLRFNRITDKGAEYIANLIKRNHSILEYNLMGNDIEEAGAKFLADAIVKSSTIKTLKMTGNKIGDFGGMQFAQAIQINESLEELDLGECDLKISSVISFATVLLCNTTLKSLNLDRPLLWTQ-QEETTVHMENMLYINKSLVELHLAKYEMRDFGMERLCDALIINRTLTVLDLSCNRITRDGAKILAKVLKCNTP 958
            T++ L D  + G     L  +L  + ++++LDL  N +   GAE +A ++  N SI    L GN   E  AK+ A+A   +  +K L ++ N+    GG    Q +  NE +E LDL    L++   ++F   L  N TLK L+L     W     E  + +   L  N +LV+L L+   + + G+  LC  L  N TL  L L+ N +T +GA  L +V+K NTP
Sbjct:  102 TRLELADNFLLGEGARYLVEMLRANFTIQNLDLSNNHLQSAGAECVAKMLLDNISIKSIKLSGNGFIEDDAKWFAEAFSSNYRVKELDLSHNQFSGKGGEYLGQMLANNEGIELLDLSWNHLRMKGAVAFCAGLKVNVTLKQLDLS----WNGFGNEGALALGEALKFNNTLVDLDLSNNRITNEGVGMLCRGLEANDTLRTLKLAYNSLTVEGALALIRVVK-NTP 323

HSP 2 Score: 85.1149 bits (209), Expect = 3.145e-17
Identity = 68/231 (29.44%), Postives = 113/231 (48.92%), Query Frame = 2

Query:  326 KGLCGILEEDESVKSLDLRFNRITDKGAEYIANLIKRNHSILEYNLMGNDIEEAGAKFLADAIVKSSTIKTLKMTGNKIGDFGGMQFAQAIQINESLEELDLGECDLKISSVISFATVLLCNTTLKSLNLDRPLLWTQ-QEETTVHMENMLYINKSLVELHLAKYEMRDFGMERLCDALIINRTLTVLDLSCNRITRDGAKILAKVLKCNTPLKVLDLGYNRIHNQGIKAI 1015
            K L   L  D     L+L  N +  +GA Y+  +++ N +I   +L  N ++ AGA+ +A  ++ + +IK++K++GN   +     FA+A   N  ++ELDL               +L  N  ++ L+L     W   + +  V     L +N +L +L L+     + G   L +AL  N TL  LDLS NRIT +G  +L + L+ N  L+ L L YN +  +G  A+
Sbjct:   89 KALAIALVTDMHTTRLELADNFLLGEGARYLVEMLRANFTIQNLDLSNNHLQSAGAECVAKMLLDNISIKSIKLSGNGFIEDDAKWFAEAFSSNYRVKELDLSHNQFSGKGGEYLGQMLANNEGIELLDLS----WNHLRMKGAVAFCAGLKVNVTLKQLDLSWNGFGNEGALALGEALKFNNTLVDLDLSNNRITNEGVGMLCRGLEANDTLRTLKLAYNSLTVEGALAL 315

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BLAST of Leucine rich repeat containing 34 vs. Ensembl Cavefish
Match: ENSAMXT00000035222.1 (ribonuclease inhibitor-like [Source:NCBI gene;Acc:103031476])

HSP 1 Score: 89.7373 bits (221), Expect = 1.220e-18
Identity = 91/334 (27.25%), Postives = 154/334 (46.11%), Query Frame = 2

Query:  290 VLTKMRLTDEHIKGLCGILEEDES-VKSLDLRFNRITDKGAEYIANLIKRNHSILE-YNLMGNDIEEAGAKFLADAIVKS-STIKTLKMTGNKIGDFGGMQFAQAIQ-INESLEELDLGECDLKISSV-ISFATVLLCNTTLKSLNLDRPLLWTQQEETTVHMENMLYINKS-LVELHLAKYEMRDFGMERLCDALI-INRTLTVLDLSCNRITRDGAKIL-----------------------------AKVLKCNTP-LKVLDLGYNRIHNQGIKAIANSLSYCNTNLKCLVITFNEIHDEGLMEITAALELNTTLDKIYIWGNEFTSDAIK 1180
            +L    LTDE  + L  IL+   S ++ LD+ +N + D G + +   +   H  L+  NL  N++E  G K L D+++   S ++TL ++G    +    Q A  +Q +N  L+ELDLG   +K S V +  A ++  +  L+ L LDR  L  +  ET   ++ +L   KS L EL L+  ++ D GM+ LCD L   N  L  ++LS N +   G ++L                             A VL+   P L  +DL  N I ++G+K + + L   N  L+ L + +  + D    ++ + L     L ++ +  N+     +K
Sbjct:   30 ILAGASLTDESCETLASILQSSNSHLRELDMSYNSLGDLGVQLLCAGLSDPHCKLQKLNLSHNNLEHIGVKLLCDSLISPHSELQTLGLSGVNFSEQSCKQMASVLQSVNTHLKELDLGCNSMKDSGVKLLSAGLMSVHCKLEKLGLDRCELENESCET---LKAVLQKPKSCLRELDLSYNKLGDLGMKHLCDGLTHPNCKLDKVNLSYNNLGHSGVEVLCGGLMNPGCNLKSIRLANVCILEGACEPLASVLESANPHLIEMDLSNNYIGDKGVKLLCSGLRSPNCKLQKLSLDWCSLTDSCCSDLASVLSSQFCLRELELGDNDLLDSGVK 360

HSP 2 Score: 54.6842 bits (130), Expect = 1.635e-7
Identity = 83/343 (24.20%), Postives = 147/343 (42.86%), Query Frame = 2

Query:  293 LTKMRLTDEHIKGLCGILEE-DESVKSLDLRFNRITDKGAEYIANLIKRNHSILE-YNLMGNDIEEAGAKFLADAIVKS-STIKTLKMTGNKIGDFGGMQFAQAI-QINESLEELDLGECDLKISSVISFATVLL---CNTTLKSLNLDRPLLWTQQEETTVHMENMLYINKSLVELHLAKYEMRDFGMERLCDAL-IINRTLTVLDLSCNRITRDGAKILAKVLKCNTPLKVLDLGYNRIHNQGIKAIANSLSYCNTNLKCLVITFNEIHDEGLMEITAALELN-TTLDKIYIWGNEFTSDAIKYFGALMD--RFRLME------SKVDVRPYSVDGIHQFA 1270
            L+ +  +++  K +  +L+  +  +K LDL  N + D G + ++  +   H  LE   L   ++E    + L   + K  S ++ L ++ NK+GD G       +   N  L++++L   +L  S V      L+   CN  LKS+ L    +     E    +  +   N  L+E+ L+   + D G++ LC  L   N  L  L L    +T      LA VL     L+ L+LG N + + G+K +   L      LK L ++   +  EG   +  AL  N + L  + I  N      +K    ++D    +LM+       K  ++P    G+ ++A
Sbjct:  118 LSGVNFSEQSCKQMASVLQSVNTHLKELDLGCNSMKDSGVKLLSAGLMSVHCKLEKLGLDRCELENESCETLKAVLQKPKSCLRELDLSYNKLGDLGMKHLCDGLTHPNCKLDKVNLSYNNLGHSGVEVLCGGLMNPGCN--LKSIRLANVCILEGACEPLASV--LESANPHLIEMDLSNNYIGDKGVKLLCSGLRSPNCKLQKLSLDWCSLTDSCCSDLASVLSSQFCLRELELGDNDLLDSGVKLLCVGLQDPKCKLKRLGLSGCCVTKEGCSSLGLALSSNHSQLKDLDISYNHPEEHGLKELSTILDNPHCKLMKLSTEYGGKCRIKP----GLQKYA 452

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BLAST of Leucine rich repeat containing 34 vs. Ensembl Sea Lamprey
Match: lrrc34 (leucine rich repeat containing 34 [Source:ZFIN;Acc:ZDB-GENE-091118-73])

HSP 1 Score: 240.736 bits (613), Expect = 2.431e-76
Identity = 131/299 (43.81%), Postives = 183/299 (61.20%), Query Frame = 2

Query:  371 LDLRFNRITDKGAEYIANLIKRNHS---ILEYNLMGNDIEEAGAKFLADAIVKSSTIKTLKMTGNKIGDFGGMQFAQAIQINESLEELDLGECDLKISSVISFATVLLCNTTLKSLNLDRPLLWTQQEETTVHMENMLYINKSLVELHLAKYEMRDFGMERLCDALIINRTLTVLDLSCNRITRDGAKILAKVLKCNTPLKVLDLGYNRIHNQGIKAIANSL-SYCNTNLKCLVITFNEIHDEGLMEITAALELNTTLDKIYIWGNEFTSDAIKYFGALMDRFRLMESKVDVRPYSVDG 1255
            L+LR N I D GAE IA+L++       +   +L  NDI   GA+ L   +  + ++ +L + GNK+G+ GG+  A A+Q N  L  LDL  CDL   S+I+F+T L  N++++ LNL RPLL++ QEETTVH+  ML  N++L  L LAK+ +RDFG  RL +AL  N +LT LDLSCN + RDGA  LA +LK  + L+VLDLG+NRI + G+ A+A ++ S   + L  LV+  N    EGL E+  A+  N TL  ++IWGN+    A + F  L+   RL E   DV  Y VDG
Sbjct:    3 LNLRCNLIADDGAEAIASLLQAQEESCWLTSLDLSLNDIGPRGARALGQVLQTNRSLMSLNLAGNKVGEEGGVSLATALQTNVGLRSLDLHHCDLGTDSIIAFSTALSYNSSVEELNLSRPLLFSLQEETTVHVARMLRANRALRTLRLAKHGVRDFGARRLSEALASNSSLTHLDLSCNLMARDGAASLALLLKQGSSLRVLDLGFNRIGDAGVTALARAVGSSGRSPLHTLVLVSNGATGEGLRELAVAMTTNRTLRSVHIWGNKLDRVACQVFAELLKSGRLKERHADVSAYEVDG 301

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BLAST of Leucine rich repeat containing 34 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002444.1 (pep scaffold:Pmarinus_7.0:GL480979:320698:340261:-1 gene:ENSPMAG00000002230.1 transcript:ENSPMAT00000002444.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 96.2857 bits (238), Expect = 3.854e-22
Identity = 75/253 (29.64%), Postives = 125/253 (49.41%), Query Frame = 2

Query:  284 NKVLTKMRLTD-----EHIKGLCGILEEDESVKSLDLRFNRITDKGAEYIANLIKRNHSILEYNLMGNDIEEAGAKFLADAIVKSSTIKTLKMTGNKIGDFGGMQFAQAIQINESLEELDLGECDLKISSVISFATVLLCNTTLKSLNLDRPLLWTQQEETTVHMENMLYINKSLVELHLAKYEMRDFGMERLCDALIINRTLTVLDLSCNRITRDGAKILAKVLKCNTPLKVLDLGYNRIHNQGIKAIANSL 1027
            N V+TK+ L+D     E  + L  +L+E+  ++ L++  NR+   GA  + + ++ N +I   NL GN++ +  A+ L +A+  + ++K L M+ N+IGD G M  A  I  +E+LE LDL     + +  ++ A  +  N +++ L+L     WT      V +E  L                       L +AL  NRTL  LDLS  R+   GA+ LA  L+ N  L+ L L  N I  +G  A+ +++
Sbjct:    1 NTVVTKLDLSDNWLQEEGCRHLSRMLKENCYIEELNVSSNRMGVGGAMALCSALRENSTITSLNLSGNNLTDEAARHLHNAMSVNRSLKELDMSHNRIGDAGAMHVAHMIANSETLETLDLAWSLWRWNGSVAIAAAISVNRSVRWLSLA----WT-----GVGIEGALA----------------------LREALQRNRTLHHLDLSSCRVDERGARALAAGLQTNVALRSLKLALNPIMAEGALALLSAI 222

HSP 2 Score: 64.6994 bits (156), Expect = 1.323e-11
Identity = 62/209 (29.67%), Postives = 98/209 (46.89%), Query Frame = 2

Query:  689 NTTLKSLNLDRPLLWTQQEETTVHMENMLYINKSLVELHLAKYEMRDFGMERLCDALIINRTLTVLDLSCNRITRDGAKILAKVLKCNTPLKVLDLGYNRIHNQGIKAIANSLSYCNTNLKCLVITFNEIHDEGLMEITAALELNTTLDKIYIWGNEFTSDAIKYFGALMDRFRLMESKVDVRPYSVDGIHQFALLPHNVDFRRYRYTA 1315
            NT +  L+L    L   QEE   H+  ML  N  + EL+++   M   G   LC AL  N T+T L+LS N +T + A+ L   +  N  LK LD+ +NRI + G   +A+ ++   T L+ L + ++     G + I AA+ +N ++  + +    +T   I+  GAL  R  L  ++          +H   L    VD R  R  A
Sbjct:    1 NTVVTKLDLSDNWL---QEEGCRHLSRMLKENCYIEELNVSSNRMGVGGAMALCSALRENSTITSLNLSGNNLTDEAARHLHNAMSVNRSLKELDMSHNRIGDAGAMHVAHMIANSET-LETLDLAWSLWRWNGSVAIAAAISVNRSVRWLSL---AWTGVGIE--GALALREALQRNRT---------LHHLDLSSCRVDERGARALA 191

[Close]

BLAST of Leucine rich repeat containing 34 vs. Ensembl Sea Lamprey
Match: lrrc74a (leucine rich repeat containing 74A [Source:ZFIN;Acc:ZDB-GENE-131127-263])

HSP 1 Score: 69.707 bits (169), Expect = 1.543e-13
Identity = 52/161 (32.30%), Postives = 80/161 (49.69%), Query Frame = 2

Query:  527 TIKTLKMTGNKIGDFGGMQFAQAIQINESLEELDLGECDLKISSVISFATVLLCNTTLKSLNLDRPLLWTQQEETTVHMENMLYINKSLVELHLAKYEMRDFGMERLCDALIINRTLTVLDLSCNRITRDGAKILAKVLKCN--TPLKVLDLGYNRIHNQG 1003
            ++K L ++ N+  + GG    Q +  NE+LEEL+L    L++   ++    L  N  L  L+L    L     E  + M   L  N +L+ L L    + + GME L   L+ N +L VL L  N  T +GA +L K +K N  + L+ LD+   R+ NQG
Sbjct:   15 SVKELDLSHNEFSEMGGEHLGQLLAHNETLEELELSWNHLRLKGAVALCAGLRVNYALTHLHLSVNGLGN---EGALAMAEALKFNGALLHLDLRNNRIGNTGMEALARGLLTNDSLRVLQLCFNIFTVEGALVLIKAVKVNEHSALERLDMSTVRV-NQG 171

HSP 2 Score: 67.781 bits (164), Expect = 7.045e-13
Identity = 46/122 (37.70%), Postives = 68/122 (55.74%), Query Frame = 2

Query:  758 HMENMLYINKSLVELHLAKYEMRDFGMERLCDALIINRTLTVLDLSCNRITRDGAKILAKVLKCNTPLKVLDLGYNRIHNQGIKAIANSLSYCNTNLKCLVITFNEIHDEGLMEITAALELN 1123
            H+  +L  N++L EL L+   +R  G   LC  L +N  LT L LS N +  +GA  +A+ LK N  L  LDL  NRI N G++A+A  L   N +L+ L + FN    EG + +  A+++N
Sbjct:   33 HLGQLLAHNETLEELELSWNHLRLKGAVALCAGLRVNYALTHLHLSVNGLGNEGALAMAEALKFNGALLHLDLRNNRIGNTGMEALARGL-LTNDSLRVLQLCFNIFTVEGALVLIKAVKVN 153

HSP 3 Score: 58.9214 bits (141), Expect = 4.968e-10
Identity = 36/125 (28.80%), Postives = 65/125 (52.00%), Query Frame = 2

Query:  341 ILEEDESVKSLDLRFNRITDKGAEYIANLIKRNHSILEYNLMGNDIEEAGAKFLADAIVKSSTIKTLKMTGNKIGDFGGMQFAQAIQINESLEELDLGECDLKISSVISFATVLLCNTTLKSLNL 715
            +L+ + SVK LDL  N  ++ G E++  L+  N ++ E  L  N +   GA  L   +  +  +  L ++ N +G+ G +  A+A++ N +L  LDL    +  + + + A  LL N +L+ L L
Sbjct:    9 LLQSNYSVKELDLSHNEFSEMGGEHLGQLLAHNETLEELELSWNHLRLKGAVALCAGLRVNYALTHLHLSVNGLGNEGALAMAEALKFNGALLHLDLRNNRIGNTGMEALARGLLTNDSLRVLQL 133

[Close]

BLAST of Leucine rich repeat containing 34 vs. Ensembl Sea Lamprey
Match: lrrc74a (leucine rich repeat containing 74A [Source:ZFIN;Acc:ZDB-GENE-131127-263])

HSP 1 Score: 69.707 bits (169), Expect = 1.633e-13
Identity = 52/162 (32.10%), Postives = 80/162 (49.38%), Query Frame = 2

Query:  527 TIKTLKMTGNKIGDFGGMQFAQAIQINESLEELDLGECDLKISSVISFATVLLCNTTLKSLNLDRPLLWTQQEETTVHMENMLYINKSLVELHLAKYEMRDFGMERLCDALIINRTLTVLDLSCNRITRDGAKILAKVLKCN--TPLKVLDLGYNRIHNQGI 1006
            ++K L ++ N+  + GG    Q +  NE+LEEL+L    L++   ++    L  N  L  L+L    L     E  + M   L  N +L+ L L    + + GME L   L+ N +L VL L  N  T +GA +L K +K N  + L+ LD+   R+ NQG 
Sbjct:   15 SVKELDLSHNEFSEMGGEHLGQLLAHNETLEELELSWNHLRLKGAVALCAGLRVNYALTHLHLSVNGLGN---EGALAMAEALKFNGALLHLDLRNNRIGNTGMEALARGLLTNDSLRVLQLCFNIFTVEGALVLIKAVKVNEHSALERLDMSTVRV-NQGF 172

HSP 2 Score: 67.781 bits (164), Expect = 7.574e-13
Identity = 46/122 (37.70%), Postives = 68/122 (55.74%), Query Frame = 2

Query:  758 HMENMLYINKSLVELHLAKYEMRDFGMERLCDALIINRTLTVLDLSCNRITRDGAKILAKVLKCNTPLKVLDLGYNRIHNQGIKAIANSLSYCNTNLKCLVITFNEIHDEGLMEITAALELN 1123
            H+  +L  N++L EL L+   +R  G   LC  L +N  LT L LS N +  +GA  +A+ LK N  L  LDL  NRI N G++A+A  L   N +L+ L + FN    EG + +  A+++N
Sbjct:   33 HLGQLLAHNETLEELELSWNHLRLKGAVALCAGLRVNYALTHLHLSVNGLGNEGALAMAEALKFNGALLHLDLRNNRIGNTGMEALARGL-LTNDSLRVLQLCFNIFTVEGALVLIKAVKVN 153

HSP 3 Score: 59.3066 bits (142), Expect = 4.003e-10
Identity = 36/125 (28.80%), Postives = 65/125 (52.00%), Query Frame = 2

Query:  341 ILEEDESVKSLDLRFNRITDKGAEYIANLIKRNHSILEYNLMGNDIEEAGAKFLADAIVKSSTIKTLKMTGNKIGDFGGMQFAQAIQINESLEELDLGECDLKISSVISFATVLLCNTTLKSLNL 715
            +L+ + SVK LDL  N  ++ G E++  L+  N ++ E  L  N +   GA  L   +  +  +  L ++ N +G+ G +  A+A++ N +L  LDL    +  + + + A  LL N +L+ L L
Sbjct:    9 LLQSNYSVKELDLSHNEFSEMGGEHLGQLLAHNETLEELELSWNHLRLKGAVALCAGLRVNYALTHLHLSVNGLGNEGALAMAEALKFNGALLHLDLRNNRIGNTGMEALARGLLTNDSLRVLQL 133

[Close]

BLAST of Leucine rich repeat containing 34 vs. Ensembl Sea Lamprey
Match: ppp1r37 (protein phosphatase 1, regulatory subunit 37 [Source:NCBI gene;Acc:562516])

HSP 1 Score: 62.7734 bits (151), Expect = 6.185e-11
Identity = 70/276 (25.36%), Postives = 129/276 (46.74%), Query Frame = 2

Query:  308 LTDEHIKGLCGILEEDESVKSLDLRFNR-ITDKGAEYIANLIKRNHSILE-YNLMGNDIEEAGAKFLADAIVKSSTIKTLKMTGNKIGDFGGMQFAQAIQINESLEELDL-------GECDLKISSVISFATVL----LCNTTLKSLNLDRP--------------LLWTQQ--EETTVHMENMLYINKSLVELHLAKYEMRDFGMERLCDALIINRTLTVLDLSCNRITRDGAKILAKVLKCNTPLKVLDLGYNRIHNQGIKAIANSLSYCNTNL 1048
            L ++    L  ++E  ES   L++ FN+ I  +G +  ANL+K+    L+  +   + + +    F+A A+   S++  L M    +     +    A+++N +L EL L       G+  L++ +++ F + L    L N +L    L                 ++W  Q       ++ +ML   +SL  L+L    + + G+ RL D LI NR++  L L+C RIT +GA  +A+ +  +  +  +DL  N +   G+ A+A +L   NT+L
Sbjct:   79 LDEDGASALFDMIEYYESAVHLNISFNKHIGVRGWQAAANLMKKKTGSLQILDARNSPVADQALPFVARALRMHSSLAVLHMENASMSGRPLLLLVSALKMNLALRELYLADNKLNSGQDALQLGNLVKFNSTLQLLDLRNNSLMDSGLQHVCEGLKEQKKGLVTLVVWNNQLSHVGMQYVASMLPCTQSLETLNLGHNSVGNEGVLRLKDGLIANRSVLRLGLACTRITCEGAVAVAEFIAESPRIVRIDLRENDVKTGGLMALALALKV-NTSL 353

HSP 2 Score: 55.0694 bits (131), Expect = 1.799e-8
Identity = 35/139 (25.18%), Postives = 73/139 (52.52%), Query Frame = 2

Query:  308 LTDEHIKGLC-GILEEDESVKSLDLRFNRITDKGAEYIANLIKRNHSILEYNLMGNDIEEAGAKFLADAIVKSSTIKTLKMTGNKIGDFGGMQFAQAIQINESLEELDLGECDLKISSVISFATVLLCNTTLKSLNLDR 721
            L D  ++ +C G+ E+ + + +L +  N+++  G +Y+A+++    S+   NL  N +   G   L D ++ + ++  L +   +I   G +  A+ I  +  +  +DL E D+K   +++ A  L  NT+L  L+LD+
Sbjct:  222 LMDSGLQHVCEGLKEQKKGLVTLVVWNNQLSHVGMQYVASMLPCTQSLETLNLGHNSVGNEGVLRLKDGLIANRSVLRLGLACTRITCEGAVAVAEFIAESPRIVRIDLRENDVKTGGLMALALALKVNTSLARLDLDK 360

[Close]

BLAST of Leucine rich repeat containing 34 vs. Ensembl Nematostella
Match: EDO33412 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SSA6])

HSP 1 Score: 259.61 bits (662), Expect = 3.125e-82
Identity = 165/384 (42.97%), Postives = 225/384 (58.59%), Query Frame = 2

Query:  140 TCERYVQFCNEKNYEVSDFIRKVFNKEKIRLINKISDENFI------YLKLCGNNK----VLTKMRLTDEHIKGLCGILEEDESVKSLDLRFNRITDKGAEYIANLIKRNHSILEYNLMGNDIEEAGAKFLADAIVKSSTIKTLKMTGNKIGDFGGMQFAQAIQINESLEELDLGECDLKISSVISFATVLLCNTTLKSLNLDRPLLWTQQEETTVHMENMLYINKSLVELHLAKYEMRDFGMERLCDALIINRTLTVLDLSCNRITRDGAKILAKVLKCNTPLKVLDLGYNRIHNQGIKAIANSLSYCNTNLKCLVITFNEIHDEGLMEITAALELNTTLDKIYIWGNEFTSDAIKYFGALMD--RFRLMESKVDVRPYSVDG 1255
            T E Y++ C EK+ E         N E + ++N   D+ F+       L+L GN +     + + RL DE    L   L+ +  V SLDL +N I D GA+ I  L++    +    L  NDI   G + +A  +  + T++ LK+ GNKIG+ GGM  A  +Q+N  LEELD+ E DLK  SVI+ ATVL  N TLK L ++RPLL++ QEETTVHM  ML +N  L ELHL  Y++RDFG ER+ + L+ N TLT L+L+ N ITRDGAK LA +LK NTPL++L+L YNRI + G  AIA +L+  NTNL  LV+  N I  +GL  +  +++ N  L  IYIWGN     A + F  L+     R+     DV+PY VDG
Sbjct:    7 TKEDYLKACGEKDREP--------NGEILAILNAAIDDQFLDPNDEFELRLHGNKRNERNEMYRRRLDDEDADILYKTLKANTFVVSLDLGYNNIGDDGAKIIGVLLQETLVLQTLILSYNDIGPEGGEIIAKGLQVNETLRVLKLNGNKIGNKGGMAIAGTLQVNTVLEELDISEVDLKTESVIAMATVLNYNNTLKVLYINRPLLFSHQEETTVHMAKMLKVNIRLRELHLTHYDIRDFGAERIMEHLVDNLTLTHLNLASNNITRDGAKQLAILLKRNTPLEMLNLAYNRIEDDGAVAIAEALAAYNTNLIKLVLCNNNIASQGLCALAKSMKSNVGLTSIYIWGNHLEEPACRAFQDLLSGGAPRIEAKDTDVQPYVVDG 382

[Close]

BLAST of Leucine rich repeat containing 34 vs. Ensembl Nematostella
Match: EDO43196 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RZ93])

HSP 1 Score: 159.073 bits (401), Expect = 4.278e-44
Identity = 126/378 (33.33%), Postives = 195/378 (51.59%), Query Frame = 2

Query:  236 NKISDENFIYL-KLCGNNKVLTKM-----RLTDEHIKGLCGILEEDESVKSLDLRFNRITDKGAEYIANLIKRNHSILEYNLMGNDI--EEAGAKFLADAIVKSSTIKTLKMTGNKIGDFGGMQFAQAIQINESLEELDLGECDLKISSVISFATVLLCNTTLKSLNLDRPLLWTQQEETTVHMENMLYINKSLVELHLAKYEMRDFGMERLCDALIINRTLTVLDLSCNRITRDGAKILAKVLKCNTPLKVLDLGYNRIHNQGIKAIANSLSYCNTNLKCLVITFNEIHDEGLMEITAALELNTTLDKIYIWGNEFTSD-AIKYFGALMDRFRLMESKVDVRPYSVDGIHQFAL---LPHNVDFRRYRYTAPIYGDD 1333
            NKI DE  I + K    N  L K+     ++ DE    +   L  + +++ LDL  N+I D GA  IA  +  N ++ + +L GN I  E+ GA  +A A++ +ST++ L + GNKIGD G +  A+A+  N +LE+LDL    +     I+ A  L+ N+TL+ L+L+   +    +E  + +   L  N +L +L L   ++ D G   +  AL+ N TL  LDL  N+I  +GA  +AK L  N+ LK LDL  N+I ++G  AIA +L   N+ LK L +  N+I DEG + I  AL  N+TL K+ + GN+   + AI    ALM    L   K+D+    +      A+   L  N   ++        GD+
Sbjct:   14 NKIGDEGAIAIAKALMTNSTLEKLDLEGNKIGDEGAIAIAKALMTNSTLEKLDLEGNKIGDDGAIAIAKALMTNSTLEKLDLEGNKIGDEDEGAIAIAKALMTNSTLEKLDLEGNKIGDEGAIAIAKALMTNSTLEKLDLEGNKIGDEGAIAIAKALMTNSTLEKLDLEGNKIG---DEGAIAIAKALMTNSTLKKLDLEGNKIGDEGAIAIAKALMTNSTLKKLDLEGNKIGDEGAIAIAKALMTNSTLKKLDLEGNKIGDEGAIAIAKAL-MTNSTLKKLDLEGNKIGDEGAIAIAKALMTNSTLKKLDLEGNKIGDEGAIAIAKALMTNSTL--KKLDLEGNKIGDEGAIAIAKALMTNSTLKKLDLEGNKIGDE 385

HSP 2 Score: 157.532 bits (397), Expect = 1.816e-43
Identity = 117/330 (35.45%), Postives = 179/330 (54.24%), Query Frame = 2

Query:  236 NKISDENFIYL-KLCGNNKVLTKMRLT-------DEHIKGLCGILEEDESVKSLDLRFNRITDKGAEYIANLIKRNHSILEYNLMGNDIEEAGAKFLADAIVKSSTIKTLKMTGNKIGDFGGMQFAQAIQINESLEELDLGECDLKISSVISFATVLLCNTTLKSLNLDRPLLWTQQEETTVHMENMLYINKSLVELHLAKYEMRDFGMERLCDALIINRTLTVLDLSCNRITRDGAKILAKVLKCNTPLKVLDLGYNRIHNQGIKAIANSLSYCNTNLKCLVITFNEIHDEGLMEITAALELNTTLDKIYIWGNEFTSD-AIKYFGALM 1198
            NKI D+  I + K    N  L K+ L        DE    +   L  + +++ LDL  N+I D+GA  IA  +  N ++ + +L GN I + GA  +A A++ +ST++ L + GNKIGD G +  A+A+  N +L++LDL    +     I+ A  L+ N+TLK L+L+   +    +E  + +   L  N +L +L L   ++ D G   +  AL+ N TL  LDL  N+I  +GA  +AK L  N+ LK LDL  N+I ++G  AIA +L   N+ LK L +  N+I DEG + I  AL  N+TL K+ + GN+   + AI    ALM
Sbjct:   70 NKIGDDGAIAIAKALMTNSTLEKLDLEGNKIGDEDEGAIAIAKALMTNSTLEKLDLEGNKIGDEGAIAIAKALMTNSTLEKLDLEGNKIGDEGAIAIAKALMTNSTLEKLDLEGNKIGDEGAIAIAKALMTNSTLKKLDLEGNKIGDEGAIAIAKALMTNSTLKKLDLEGNKIG---DEGAIAIAKALMTNSTLKKLDLEGNKIGDEGAIAIAKALMTNSTLKKLDLEGNKIGDEGAIAIAKALMTNSTLKKLDLEGNKIGDEGAIAIAKAL-MTNSTLKKLDLEGNKIGDEGAIAIAKALMTNSTLKKLDLEGNKIGDEGAIAIAKALM 395

HSP 3 Score: 152.91 bits (385), Expect = 1.031e-41
Identity = 114/334 (34.13%), Postives = 178/334 (53.29%), Query Frame = 2

Query:  359 SVKSLDLRFNRITDKGAEYIANLIKRNHSILEYNLMGNDIEEAGAKFLADAIVKSSTIKTLKMTGNKIGDFGGMQFAQAIQINESLEELDL-----GECDLKISSVISFATVLLCNTTLKSLNLDRPLLWTQQEETTVHMENMLYINKSLVELHLAKYEMRDFGMERLCDALIINRTLTVLDLSCNRITRDGAKILAKVLKCNTPLKVLDLGYNRIHNQGIKAIANSLSYCNTNLKCLVITFNEIHDEGLMEITAALELNTTLDKIYIWGNEFTSD-AIKYFGALMDRFRLMESKVDVRPYSVDGIHQFAL---LPHNVDFRRYRYTAPIYGDD 1333
            +++ LDL  N+I D+GA  IA  +  N ++ + +L GN I + GA  +A A++ +ST++ L + GNKIGD G +  A+A+  N +LE+LDL     G+ D      I+ A  L+ N+TL+ L+L+   +    +E  + +   L  N +L +L L   ++ D G   +  AL+ N TL  LDL  N+I  +GA  +AK L  N+ LK LDL  N+I ++G  AIA +L   N+ LK L +  N+I DEG + I  AL  N+TL K+ + GN+   + AI    ALM    L   K+D+    +      A+   L  N   ++        GD+
Sbjct:    5 TLEKLDLEGNKIGDEGAIAIAKALMTNSTLEKLDLEGNKIGDEGAIAIAKALMTNSTLEKLDLEGNKIGDDGAIAIAKALMTNSTLEKLDLEGNKIGDED---EGAIAIAKALMTNSTLEKLDLEGNKIG---DEGAIAIAKALMTNSTLEKLDLEGNKIGDEGAIAIAKALMTNSTLEKLDLEGNKIGDEGAIAIAKALMTNSTLKKLDLEGNKIGDEGAIAIAKAL-MTNSTLKKLDLEGNKIGDEGAIAIAKALMTNSTLKKLDLEGNKIGDEGAIAIAKALMTNSTL--KKLDLEGNKIGDEGAIAIAKALMTNSTLKKLDLEGNKIGDE 329

HSP 4 Score: 147.902 bits (372), Expect = 6.101e-40
Identity = 107/305 (35.08%), Postives = 165/305 (54.10%), Query Frame = 2

Query:  236 NKISDEN---FIYLKLCGNNKVLTKM-----RLTDEHIKGLCGILEEDESVKSLDLRFNRITDKGAEYIANLIKRNHSILEYNLMGNDIEEAGAKFLADAIVKSSTIKTLKMTGNKIGDFGGMQFAQAIQINESLEELDLGECDLKISSVISFATVLLCNTTLKSLNLDRPLLWTQQEETTVHMENMLYINKSLVELHLAKYEMRDFGMERLCDALIINRTLTVLDLSCNRITRDGAKILAKVLKCNTPLKVLDLGYNRIHNQGIKAIANSLSYCNTNLKCLVITFNEIHDEGLMEITAALELNT 1126
            NKI DE+       K    N  L K+     ++ DE    +   L  + +++ LDL  N+I D+GA  IA  +  N ++ + +L GN I + GA  +A A++ +ST+K L + GNKIGD G +  A+A+  N +L++LDL    +     I+ A  L+ N+TLK L+L+   +    +E  + +   L  N +L +L L   ++ D G   +  AL+ N TL  LDL  N+I  +GA  +AK L  N+ LK LDL  N+I ++G  AIA +L   N+ LK L +  N+I DEG + I  AL  N+
Sbjct:   98 NKIGDEDEGAIAIAKALMTNSTLEKLDLEGNKIGDEGAIAIAKALMTNSTLEKLDLEGNKIGDEGAIAIAKALMTNSTLEKLDLEGNKIGDEGAIAIAKALMTNSTLKKLDLEGNKIGDEGAIAIAKALMTNSTLKKLDLEGNKIGDEGAIAIAKALMTNSTLKKLDLEGNKIG---DEGAIAIAKALMTNSTLKKLDLEGNKIGDEGAIAIAKALMTNSTLKKLDLEGNKIGDEGAIAIAKALMTNSTLKKLDLEGNKIGDEGAIAIAKAL-MTNSTLKKLDLEGNKIGDEGAIAIAKALMTNS 398

[Close]

BLAST of Leucine rich repeat containing 34 vs. Ensembl Nematostella
Match: EDO35561 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SL68])

HSP 1 Score: 119.398 bits (298), Expect = 1.917e-30
Identity = 90/269 (33.46%), Postives = 141/269 (52.42%), Query Frame = 2

Query:  353 DESVKSLDLRFNRITDKGAEYIANLIKRNHSILEYNLMGNDIEEAGAKFLADAIVKSSTIKTLKMTGNKIGDFGGMQFAQAIQINESLEELDLGECDLKISSVISFATVLLCNTTLKSLNLD----RPLLWTQQEETTVHMENMLYINKSLVELHLAKYEMRDFGMERLCDALIINRTLTVLDLSCNRITRDGAKILAKVLKCNTPLKVLDLGYNRIHNQGIKAIANSLSYCNTNLKCLVITFNEIHDEGLMEITAALELNTTLDKIYI 1147
            + S+  LDL  N+I+ KGA  IA ++ +N  +  + L  N I + GA  +A+A+  +ST+K L +T N IG+ G    A+A+  N +L+E DL + ++     I+ A  L+ N+TLK L L     R +       T +H         SL+ L L+  ++   G   + + L  N+ L    L   +I  +GA  +A  L  N+ LK LDL  N I ++G KAIA +L   N+ LK L +  + I DEG + I  AL  N+TL K+++
Sbjct:    9 EPSLIDLDLSLNKISSKGAIAIAEMLSKNQLLETFRLSFNQIGDEGAIAIANALKTNSTLKILDLTKNNIGNEGAKAIAEALMTNSTLKEFDLCDTNIGDEGAIAIANALMTNSTLKKLYLHDYGIRAVGIAALARTQLH-------KPSLIGLDLSSNQISSKGAIAIAEMLSKNQLLETFRLCLYQIGDEGAIAIANALMTNSTLKKLDLEGNYIGDEGAKAIAEAL-MTNSTLKELHLYESNIGDEGAIAIANALMTNSTLKKLHL 269

HSP 2 Score: 109.383 bits (272), Expect = 6.541e-27
Identity = 82/257 (31.91%), Postives = 138/257 (53.70%), Query Frame = 2

Query:  341 ILEEDESVKSLDLRFNRITDKGAEYIANLIKRNHSILEYNLMGNDIEEAGAKFLADAIVKSSTIKTLKMTGNKIGDFGGMQFAQAIQINESLEELDLGECDLKISSVISFATVLLCNTTLKSLNLDRPLLWTQQEETTVHMENMLYINKSLVELHLAKYEMRDFGMERLCDALIINRTLTVLDLSCNRITRDGAKILAKVLKCNTPLKVLDLGYNRIHNQGIKAIANSLSYCNTNLKCLVITFNEIHDEGLMEITAA 1111
            +L +++ +++  L FN+I D+GA  IAN +K N ++   +L  N+I   GAK +A+A++ +ST+K   +    IGD G +  A A+  N +L++L L +  ++   + + A   L   +L  L+L    + ++     + +  ML  N+ L    L  Y++ D G   + +AL+ N TL  LDL  N I  +GAK +A+ L  N+ LK L L  + I ++G  AIAN+L   N+ LK L      +H  G+  + AA
Sbjct:   33 MLSKNQLLETFRLSFNQIGDEGAIAIANALKTNSTLKILDLTKNNIGNEGAKAIAEALMTNSTLKEFDLCDTNIGDEGAIAIANALMTNSTLKKLYLHDYGIRAVGIAALARTQLHKPSLIGLDLSSNQISSKG---AIAIAEMLSKNQLLETFRLCLYQIGDEGAIAIANALMTNSTLKKLDLEGNYIGDEGAKAIAEALMTNSTLKELHLYESNIGDEGAIAIANAL-MTNSTLKKL-----HLHTYGIRAVGAA 280

[Close]

BLAST of Leucine rich repeat containing 34 vs. Ensembl Nematostella
Match: EDO31478 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SXT1])

HSP 1 Score: 100.138 bits (248), Expect = 5.665e-23
Identity = 90/306 (29.41%), Postives = 138/306 (45.10%), Query Frame = 2

Query:  152 YVQFCNEKNY-EVSDFIRKVFNKE-------------KIRLINKISDENFIYLKLCGNNKVLTKMRLTDEHIKGLCGILEEDESVKSLDLRFNRITDKGAEYIANLIKRNHSILEYNLMGNDIEEAGAKFLADAIVKSSTIKTLKMTGNKIGDFGGMQFAQAIQINESLEELDLGECDLKISSVISFATVLLCNTTLKSLNLDRPLLWTQQEETTVHMENMLYINKSLVELHLAKYEMRDFGMERLCDALIINRTLTVLDLSCNRITRDGAKILAKVLKCNTPLKVLDLGYNRIHNQGIKAIANSL 1027
            Y+Q C E     VS F+R +   E             K   I  +S+ + + L L  N           E ++  C I +    V S D+  N++ D G+E IA+++  N +I      GN  +E  AK LA+AI  ++ +K L ++ NK G+  G++ A A+  NE++ EL+L    L+     + A  L  N TLK LN    L W                               + G   + +AL +N +L  LDL+ NRIT +GA +L K L  NT L+VL +G N + + G  AI N++
Sbjct:   11 YIQACREAGVIPVSYFLRNMLEAEVDIKHHGLGAMGSKAIAIALVSNTSVVKLNLSDNWMGPEGASYVAEMLRENCYITDLLCEVLSDDMSENKLGDHGSESIADVLLHNPNIHRLTANGNGFDEKAAKILAEAIKLNNRLKYLCLSHNKFGEKAGLELAPALAANETISELNLSWNHLRNRGACAIALSLKENITLKILN----LAWNG---------------------------FGNDGALAMGEALKVNASLLELDLTNNRITAEGAVLLGKGLTINTTLQVLKIGKNPMQSAGAYAILNAM 285

HSP 2 Score: 73.1738 bits (178), Expect = 4.923e-14
Identity = 69/258 (26.74%), Postives = 118/258 (45.74%), Query Frame = 2

Query:  371 LDLRFNRITDKGAEYIANLIKRNHSILEYNLMGNDIEEAGAKFLADAIVKSSTIKTL-------KMTGNKIGDFGGMQFAQAIQINESLEELDLGECDLKISSVISFATVLLCNTTLKSLNLDRPLLWTQQEETTVHMENMLYINKSLVELHLAKYEMRDFGMERLCDALIINRTLTVLDLSCNRITRDGAKILAKVLKCNTPLKVLDLGYNRIHNQGIKAIANSLSYCNTNLKCLVITFNEIHDEGLMEITAALELN 1123
            +D++ + +   G++ IA  +  N S+++ NL  N +   GA ++A+ + ++  I  L        M+ NK+GD G    A  +  N ++  L          +    A  +  N  LK L L         E+  + +   L  N+++ EL+L+   +R+ G   +  +L  N TL +L+L+ N    DGA  + + LK N  L  LDL  NRI  +G   +   L+  NT L+ L I  N +   G   I  A++ N
Sbjct:   35 VDIKHHGLGAMGSKAIAIALVSNTSVVKLNLSDNWMGPEGASYVAEMLRENCYITDLLCEVLSDDMSENKLGDHGSESIADVLLHNPNIHRLTANGNGFDEKAAKILAEAIKLNNRLKYLCLSHNKF---GEKAGLELAPALAANETISELNLSWNHLRNRGACAIALSLKENITLKILNLAWNGFGNDGALAMGEALKVNASLLELDLTNNRITAEGAVLLGKGLT-INTTLQVLKIGKNPMQSAGAYAILNAMKNN 288

[Close]

BLAST of Leucine rich repeat containing 34 vs. Ensembl Nematostella
Match: EDO36360 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SIU1])

HSP 1 Score: 96.6709 bits (239), Expect = 9.988e-22
Identity = 77/265 (29.06%), Postives = 119/265 (44.91%), Query Frame = 2

Query:  332 LCGILEEDESVKSLDLRFNRITDKGAEYIANLIKRNHSILEYNLMGNDIEEAGAKFLADAIVKSSTIKTLKMTGNKIGDFGGMQFAQAIQINESLEELDLGECDLKISSVISFATVLLCNTTLKSLNLDRPLLWTQQEETTVHMENMLYINKSLVELHLAKYEMRDFGMERLCDALIINRTLTVLDLSCNRITRDGAKILAKVLKCNTPLKVLDLGYNRIHNQGIKAIANSLSYCNTNLKCLVITFNEIHDEGLMEITAALELNT 1126
            L   L +  +V+ LDL  NR+ ++GAE  A ++K N  I E NL GN +   GAK + + I  S+ I+ L ++ N   D  G   ++ +    +L+EL L       S     A  +  N +++ L+L     W                             +R  G   +C A+  N ++ VLDLS N    DGA  +   L+ N+ LK LDL +NRI  +G  A++  L+  N  L+ L I FN    +G M +  A+  N 
Sbjct:   56 LARALAKSTTVEKLDLEENRLQEEGAESFAKMLKDNCYITELNLAGNAMSSRGAKAMGEIIGYSNYIRKLDLSFNNFIDKDGEALSKGLAATLTLKELRLSHNSFSESGGELLAPGIAANYSVEYLDLS----WNH---------------------------LRMKGAIAICKAMGENASIRVLDLSWNGFADDGAAAMGNALRHNSTLKELDLSHNRITKKGAFALSKGLA-VNDALRVLKIGFNPFESDGTMALLKAMRNNA 288

HSP 2 Score: 73.559 bits (179), Expect = 3.894e-14
Identity = 64/244 (26.23%), Postives = 116/244 (47.54%), Query Frame = 2

Query:  533 KTLKMTGNKIGDFGGMQFAQAIQINESLEELDLGECDLKISSVISFATVLLCNTTLKSLNLDRPLLWTQQEETTVHMENMLYINKSLVELHLAKYEMRDFGMERLCDALIINRTLTVLDLSCNRITRDGAKILAKVLKCNTPLKVLDLGYNRIHNQGIKAIANSLSYCNTNLKCLVITFNEIHDEGLMEITAALELNTTLDKIYIWGNEFTSD---AIKYFGALMDRFRLMESKVDVRPYSVDG 1255
            K + +  + +G  G M  A+A+  + ++E+LDL E  L+     SFA +L  N  +  LNL    + ++  +    M  ++  +  + +L L+     D   E L   L    TL  L LS N  +  G ++LA  +  N  ++ LDL +N +  +G  AI  ++   N +++ L +++N   D+G   +  AL  N+TL ++ +  N  T     A+    A+ D  R++  K+   P+  DG
Sbjct:   39 KEISLAHHGLGPRGAMALARALAKSTTVEKLDLEENRLQEEGAESFAKMLKDNCYITELNLAGNAMSSRGAKA---MGEIIGYSNYIRKLDLSFNNFIDKDGEALSKGLAATLTLKELRLSHNSFSESGGELLAPGIAANYSVEYLDLSWNHLRMKGAIAICKAMGE-NASIRVLDLSWNGFADDGAAAMGNALRHNSTLKELDLSHNRITKKGAFALSKGLAVNDALRVL--KIGFNPFESDG 276

[Close]

BLAST of Leucine rich repeat containing 34 vs. Ensembl Medaka
Match: lrrc34 (leucine rich repeat containing 34 [Source:NCBI gene;Acc:101175273])

HSP 1 Score: 234.958 bits (598), Expect = 7.768e-72
Identity = 137/373 (36.73%), Postives = 220/373 (58.98%), Query Frame = 2

Query:  152 YVQFCNEK----NYEVSDFIRKVFNKEKIRLINKISDENFIYLKLCGNNKVLTKMRLTDEHIKGLCGILEEDESVKSLDLRFNRITDKGAEYIANLIKRNHSILEY-NLMGNDIEEAGAKFLADAIVKSSTIKTLKMTGNKIGDFGGMQFAQAIQINESLEELDLGECDLKISSVISFATVLLCNTTLKSLNLDRPLLWTQQEETTVHMENMLYINKSLVELHLAKYEMRDFGMERLCDALIINRTLTVLDLSCNRITRDGAKILAKVLKCNTPLKVLDLGYNRIHNQGIKAIANSLSYCNTNLKCLVITFNEIHDEGLMEITAALELNTTLDKIYIWGNEFTSDAIKYFGALMDRFRLMESKVDVRPYSVDG 1255
            Y +FC +     N +V + + K F    + L    +      L L GN     + RL DE +  L   L+ D  V  LD+ +N I+D GA+++A+ ++ + S L++ +L  N+I+  GA+FLA+++  +S++ +L ++GN+ GD GG+  ++ +Q+N +L+ L L +C+L   SV +    L  NT L++L++ RPLL+++QEE  VH   ML +N SL+ELHL +  + D GME L + L  NR+L  LDL CNR+TRDGA  LA+VLK +  L+++DL  NRI ++G   ++ +++    +LK L +  N I  EGL+ +  A++ N +L  IY+WGN       + F  L+   RL+    DV PY VDG
Sbjct:   54 YQEFCVQLKININKDVLEILDKTFKSGSVCLSRTFT------LDLPGNGGRRAQ-RLEDEDVLVLSKCLQNDGRVTGLDVSYNNISDGGAKHLADALQLSSSALKFLDLKFNNIQADGAEFLANSLKSNSSLLSLSLSGNRFGDRGGVSMSRMLQVNSTLQMLQLSDCNLADRSVAALGAALNRNTALQALDISRPLLFSRQEEWAVHFSQMLTVNCSLLELHLGRMGLTDSGMETLAEGLTRNRSLRYLDLRCNRVTRDGAHHLAEVLKQSKTLEIIDLSSNRIEDEGAVHLSEAMATHGCSLKELSVCRNCIRTEGLLSLAQAVKHNQSLTHIYVWGNRLDEPVCQVFSELISSGRLLPEHTDVSPYQVDG 419

[Close]

BLAST of Leucine rich repeat containing 34 vs. Ensembl Medaka
Match: nlrc3 (NLR family CARD domain containing 3 [Source:NCBI gene;Acc:101165263])

HSP 1 Score: 117.087 bits (292), Expect = 1.972e-27
Identity = 98/325 (30.15%), Postives = 161/325 (49.54%), Query Frame = 2

Query:  293 LTKMRLTDEHI-----KGLCGILEEDESVKSLDLRFNRITDKGAEYIANLIKRNHSILEYNLMGNDIEEAGAKFLADAIVKSSTIKTLKMTGNKIGDFGGMQFAQAIQINESLEELDLGECDLKISSVISFATVLLCNTTLKSLNLDRPLLWTQQEETTVHMENMLYINKSLVELHLAKYEMRDFGMERLCDALIINRTLTVLDLSCNRITRDGAKILAKVLKCNTPLKVLDLGYNRIHNQGIKAIANSLSYCNTNLKCLVITFNEIHDEGLMEITAALELNTTLDKIYIWG-NEFTSDAIKYFGALMDRFRLMESKVDVRPYSV 1249
            + K+ L D  I     K L   L  + ++  L+LR N I  KGA+++A  +K N  +   N   N IEE GA+ LA+ +  +  + +L +  NKIG  G  + A A+++N++L +L L    L     ++ A  L  N TL SL L    +          +   L  N  LV L+L +  +   G + +  AL  N +L  LDL+ N +  +G + ++  +K N  L  L L +N I +   K +AN+L   N  +K L +  N I +EG++ +  AL++NT+L  + + G +  TS A+    ALM+   L    +D+R  S+
Sbjct:  736 IQKLSLADNAISNKGAKALSRALLVNRTLTYLNLRNNNIGSKGAKFLAEALKMNQVLTSINFQNNSIEEEGAQALAEVLQCNRKLVSLNVRKNKIGADGAKRIADALKMNQTLTKLILCSNQLGDKGTVALAEALKLNQTLLSLQLQSNSI---SNRGMTALTKALRFNHGLVTLNLRENSIGIEGAKNMAQALKENNSLQNLDLTANLLHDEGVQAISAAIKFNQGLTSLHLQWNFIKSTATKVLANAL-MSNATIKLLDLQENAIGNEGVIFLAEALKVNTSLQTLCLQGVSAGTSGAVALAEALMENQSLQ--TLDLRGNSI 1054

HSP 2 Score: 108.997 bits (271), Expect = 1.075e-24
Identity = 87/304 (28.62%), Postives = 150/304 (49.34%), Query Frame = 2

Query:  284 NKVLTKMRLTDEHI-----KGLCGILEEDESVKSLDLRFNRITDKGAEYIANLIKRNHSILEYNLMGNDIEEAGAKFLADAIVKSSTIKTLKMTGNKIGDFGGMQFAQAIQINESLEELDLGECDLKISSVISFATVLLCNTTLKSLNLDRPLLWTQQEETTVHMENMLYINKSLVELHLAKYEMRDFGMERLCDALIINRTLTVLDLSCNRITRDGAKILAKVLKCNTPLKVLDLGYNRIHNQGIKAIANSLSYCNTNLKCLVITFNEIHDEGLMEITAALELNTTLDKIYIWGNEFTSDAIK 1180
            N+ LT + L + +I     K L   L+ ++ + S++ + N I ++GA+ +A +++ N  ++  N+  N I   GAK +ADA+  + T+  L +  N++GD G +  A+A+++N++L  L L    +    + +    L  N  L +LNL    +     E   +M   L  N SL  L L    + D G++ +  A+  N+ LT L L  N I     K+LA  L  N  +K+LDL  N I N+G+  +A +L   NT+L+ L +        G + +  AL  N +L  + + GN    +  K
Sbjct:  761 NRTLTYLNLRNNNIGSKGAKFLAEALKMNQVLTSINFQNNSIEEEGAQALAEVLQCNRKLVSLNVRKNKIGADGAKRIADALKMNQTLTKLILCSNQLGDKGTVALAEALKLNQTLLSLQLQSNSISNRGMTALTKALRFNHGLVTLNLRENSIGI---EGAKNMAQALKENNSLQNLDLTANLLHDEGVQAISAAIKFNQGLTSLHLQWNFIKSTATKVLANALMSNATIKLLDLQENAIGNEGVIFLAEALK-VNTSLQTLCLQGVSAGTSGAVALAEALMENQSLQTLDLRGNSIGMEGAK 1060

HSP 3 Score: 108.227 bits (269), Expect = 1.971e-24
Identity = 80/253 (31.62%), Postives = 129/253 (50.99%), Query Frame = 2

Query:  284 NKVLTKM-----RLTDEHIKGLCGILEEDESVKSLDLRFNRITDKGAEYIANLIKRNHSILEYNLMGNDIEEAGAKFLADAIVKSSTIKTLKMTGNKIGDFGGMQFAQAIQINESLEELDLGECDLKISSVISFATVLLCNTTLKSLNLDRPLLWTQQEETTVHMENMLYINKSLVELHLAKYEMRDFGMERLCDALIINRTLTVLDLSCNRITRDGAKILAKVLKCNTPLKVLDLGYNRIHNQGIKAIANSL 1027
            N+ LTK+     +L D+    L   L+ ++++ SL L+ N I+++G   +   ++ NH ++  NL  N I   GAK +A A+ ++++++ L +T N + D G    + AI+ N+ L  L L    +K ++    A  L+ N T+K L+L    +     E  + +   L +N SL  L L        G   L +AL+ N++L  LDL  N I  +GAK LA  LKCN  LK L+L  N +   G   IA +L
Sbjct:  845 NQTLTKLILCSNQLGDKGTVALAEALKLNQTLLSLQLQSNSISNRGMTALTKALRFNHGLVTLNLRENSIGIEGAKNMAQALKENNSLQNLDLTANLLHDEGVQAISAAIKFNQGLTSLHLQWNFIKSTATKVLANALMSNATIKLLDLQENAI---GNEGVIFLAEALKVNTSLQTLCLQGVSAGTSGAVALAEALMENQSLQTLDLRGNSIGMEGAKALANALKCNRSLKSLNLQENSLGMDGAIFIATAL 1094

HSP 4 Score: 85.1149 bits (209), Expect = 4.941e-17
Identity = 64/215 (29.77%), Postives = 105/215 (48.84%), Query Frame = 2

Query:  317 EHIKGLCGILEEDESVKSLDLRFNRITDKGAEYIANLIKRNHSILEYNLMGNDIEEAGAKFLADAIVKSSTIKTLKMTGNKIGDFGGMQFAQAIQINESLEELDLGECDLKISSVISFATVLLCNTTLKSLNLDRPLLWTQQEETTVHMENMLYINKSLVELHLAKYEMRDFGMERLCDALIINRTLTVLDLSCNRITRDGAKILAKVLKCNTPL 961
            E  K +   L+E+ S+++LDL  N + D+G + I+  IK N  +   +L  N I+    K LA+A++ ++TIK L +  N IG+ G +  A+A+++N SL+ L L       S  ++ A  L+ N +L++L+L            ++ ME                      G + L +AL  NR+L  L+L  N +  DGA  +A  LK N  L
Sbjct:  917 EGAKNMAQALKENNSLQNLDLTANLLHDEGVQAISAAIKFNQGLTSLHLQWNFIKSTATKVLANALMSNATIKLLDLQENAIGNEGVIFLAEALKVNTSLQTLCLQGVSAGTSGAVALAEALMENQSLQTLDL---------RGNSIGME----------------------GAKALANALKCNRSLKSLNLQENSLGMDGAIFIATALKGNHQL 1100

HSP 5 Score: 79.337 bits (194), Expect = 3.024e-15
Identity = 53/180 (29.44%), Postives = 92/180 (51.11%), Query Frame = 2

Query:  293 LTKMRLTDEHIKGLCGILEEDESVKSLDLRFNRITDKGAEYIANLIKRNHSILEYNLMGNDIEEAGAKFLADAIVKSSTIKTLKMTGNKIGDFGGMQFAQAIQINESLEELDLGECDLKISSVISFATVLLCNTTLKSLNLDRPLLWTQQEETTVHMENMLYINKSLVELHLAKYEMRDF 832
            LT   L DE ++ +   ++ ++ + SL L++N I     + +AN +  N +I   +L  N I   G  FLA+A+  +++++TL + G   G  G +  A+A+  N+SL+ LDL    + +    + A  L CN +LKSLNL         +E ++ M+  ++I  +L   H   Y   DF
Sbjct:  937 LTANLLHDEGVQAISAAIKFNQGLTSLHLQWNFIKSTATKVLANALMSNATIKLLDLQENAIGNEGVIFLAEALKVNTSLQTLCLQGVSAGTSGAVALAEALMENQSLQTLDLRGNSIGMEGAKALANALKCNRSLKSLNL---------QENSLGMDGAIFIATALKGNHQLAYIKYDF 1107

[Close]

Query:  293 LTKMRLTDEHI-----KGLCGILEEDESVKSLDLRFNRITDKGAEYIANLIKRNHSILEYNLMGNDIEEAGAKFLADAIVKSSTIKTLKMTGNKIGDFGGMQFAQAIQINESLEELDLGECDLKISSVISFATVLLCNTTLKSLNLDRPLLWTQQEETTVHMENMLYINKSLVELHLAKYEMRDFGMERLCDALIINRTLTVLDLSCNRITRDGAKILAKVLKCNTPLKVLDLGYNRIHNQGIKAIANSLSYCNTNLKCLVITFNEIHDEGLMEITAALELNTTLDKIYIWG-NEFTSDAIKYFGALMDRFRLMESKVDVRPYSV 1249
            + K+ L D  I     K L   L  + ++  L+LR N I  KGA+++A  +K N  +   N   N IEE GA+ LA+ +  +  + +L +  NKIG  G  + A A+++N++L +L L    L     ++ A  L  N TL SL L    +          +   L  N  LV L+L +  +   G + +  AL  N +L  LDL+ N +  +G + ++  +K N  L  L L +N I +   K +AN+L   N  +K L +  N I +EG++ +  AL++NT+L  + + G +  TS A+    ALM+   L    +D+R  S+
Sbjct:  736 IQKLSLADNAISNKGAKALSRALLVNRTLTYLNLRNNNIGSKGAKFLAEALKMNQVLTSINFQNNSIEEEGAQALAEVLQCNRKLVSLNVRKNKIGADGAKRIADALKMNQTLTKLILCSNQLGDKGTVALAEALKLNQTLLSLQLQSNSI---SNRGMTALTKALRFNHGLVTLNLRENSIGIEGAKNMAQALKENNSLQNLDLTANLLHDEGVQAISAAIKFNQGLTSLHLQWNFIKSTATKVLANAL-MSNATIKLLDLQENAIGNEGVIFLAEALKVNTSLQTLCLQGVSAGTSGAVALAEALMENQSLQ--TLDLRGNSI 1054

HSP 2 Score: 108.997 bits (271), Expect = 1.075e-24
Identity = 87/304 (28.62%), Postives = 150/304 (49.34%), Query Frame = 2

Query:  284 NKVLTKMRLTDEHI-----KGLCGILEEDESVKSLDLRFNRITDKGAEYIANLIKRNHSILEYNLMGNDIEEAGAKFLADAIVKSSTIKTLKMTGNKIGDFGGMQFAQAIQINESLEELDLGECDLKISSVISFATVLLCNTTLKSLNLDRPLLWTQQEETTVHMENMLYINKSLVELHLAKYEMRDFGMERLCDALIINRTLTVLDLSCNRITRDGAKILAKVLKCNTPLKVLDLGYNRIHNQGIKAIANSLSYCNTNLKCLVITFNEIHDEGLMEITAALELNTTLDKIYIWGNEFTSDAIK 1180
            N+ LT + L + +I     K L   L+ ++ + S++ + N I ++GA+ +A +++ N  ++  N+  N I   GAK +ADA+  + T+  L +  N++GD G +  A+A+++N++L  L L    +    + +    L  N  L +LNL    +     E   +M   L  N SL  L L    + D G++ +  A+  N+ LT L L  N I     K+LA  L  N  +K+LDL  N I N+G+  +A +L   NT+L+ L +        G + +  AL  N +L  + + GN    +  K
Sbjct:  761 NRTLTYLNLRNNNIGSKGAKFLAEALKMNQVLTSINFQNNSIEEEGAQALAEVLQCNRKLVSLNVRKNKIGADGAKRIADALKMNQTLTKLILCSNQLGDKGTVALAEALKLNQTLLSLQLQSNSISNRGMTALTKALRFNHGLVTLNLRENSIGI---EGAKNMAQALKENNSLQNLDLTANLLHDEGVQAISAAIKFNQGLTSLHLQWNFIKSTATKVLANALMSNATIKLLDLQENAIGNEGVIFLAEALK-VNTSLQTLCLQGVSAGTSGAVALAEALMENQSLQTLDLRGNSIGMEGAK 1060

HSP 3 Score: 108.227 bits (269), Expect = 1.971e-24
Identity = 80/253 (31.62%), Postives = 129/253 (50.99%), Query Frame = 2

Query:  284 NKVLTKM-----RLTDEHIKGLCGILEEDESVKSLDLRFNRITDKGAEYIANLIKRNHSILEYNLMGNDIEEAGAKFLADAIVKSSTIKTLKMTGNKIGDFGGMQFAQAIQINESLEELDLGECDLKISSVISFATVLLCNTTLKSLNLDRPLLWTQQEETTVHMENMLYINKSLVELHLAKYEMRDFGMERLCDALIINRTLTVLDLSCNRITRDGAKILAKVLKCNTPLKVLDLGYNRIHNQGIKAIANSL 1027
            N+ LTK+     +L D+    L   L+ ++++ SL L+ N I+++G   +   ++ NH ++  NL  N I   GAK +A A+ ++++++ L +T N + D G    + AI+ N+ L  L L    +K ++    A  L+ N T+K L+L    +     E  + +   L +N SL  L L        G   L +AL+ N++L  LDL  N I  +GAK LA  LKCN  LK L+L  N +   G   IA +L
Sbjct:  845 NQTLTKLILCSNQLGDKGTVALAEALKLNQTLLSLQLQSNSISNRGMTALTKALRFNHGLVTLNLRENSIGIEGAKNMAQALKENNSLQNLDLTANLLHDEGVQAISAAIKFNQGLTSLHLQWNFIKSTATKVLANALMSNATIKLLDLQENAI---GNEGVIFLAEALKVNTSLQTLCLQGVSAGTSGAVALAEALMENQSLQTLDLRGNSIGMEGAKALANALKCNRSLKSLNLQENSLGMDGAIFIATAL 1094

HSP 4 Score: 85.1149 bits (209), Expect = 4.941e-17
Identity = 64/215 (29.77%), Postives = 105/215 (48.84%), Query Frame = 2

Query:  317 EHIKGLCGILEEDESVKSLDLRFNRITDKGAEYIANLIKRNHSILEYNLMGNDIEEAGAKFLADAIVKSSTIKTLKMTGNKIGDFGGMQFAQAIQINESLEELDLGECDLKISSVISFATVLLCNTTLKSLNLDRPLLWTQQEETTVHMENMLYINKSLVELHLAKYEMRDFGMERLCDALIINRTLTVLDLSCNRITRDGAKILAKVLKCNTPL 961
            E  K +   L+E+ S+++LDL  N + D+G + I+  IK N  +   +L  N I+    K LA+A++ ++TIK L +  N IG+ G +  A+A+++N SL+ L L       S  ++ A  L+ N +L++L+L            ++ ME                      G + L +AL  NR+L  L+L  N +  DGA  +A  LK N  L
Sbjct:  917 EGAKNMAQALKENNSLQNLDLTANLLHDEGVQAISAAIKFNQGLTSLHLQWNFIKSTATKVLANALMSNATIKLLDLQENAIGNEGVIFLAEALKVNTSLQTLCLQGVSAGTSGAVALAEALMENQSLQTLDL---------RGNSIGME----------------------GAKALANALKCNRSLKSLNLQENSLGMDGAIFIATALKGNHQL 1100

HSP 5 Score: 79.337 bits (194), Expect = 3.024e-15
Identity = 53/180 (29.44%), Postives = 92/180 (51.11%), Query Frame = 2

Query:  293 LTKMRLTDEHIKGLCGILEEDESVKSLDLRFNRITDKGAEYIANLIKRNHSILEYNLMGNDIEEAGAKFLADAIVKSSTIKTLKMTGNKIGDFGGMQFAQAIQINESLEELDLGECDLKISSVISFATVLLCNTTLKSLNLDRPLLWTQQEETTVHMENMLYINKSLVELHLAKYEMRDF 832
            LT   L DE ++ +   ++ ++ + SL L++N I     + +AN +  N +I   +L  N I   G  FLA+A+  +++++TL + G   G  G +  A+A+  N+SL+ LDL    + +    + A  L CN +LKSLNL         +E ++ M+  ++I  +L   H   Y   DF
Sbjct:  937 LTANLLHDEGVQAISAAIKFNQGLTSLHLQWNFIKSTATKVLANALMSNATIKLLDLQENAIGNEGVIFLAEALKVNTSLQTLCLQGVSAGTSGAVALAEALMENQSLQTLDLRGNSIGMEGAKALANALKCNRSLKSLNL---------QENSLGMDGAIFIATALKGNHQLAYIKYDF 1107

[Close]

BLAST of Leucine rich repeat containing 34 vs. Ensembl Medaka
Match: lrrc74a (leucine rich repeat containing 74A [Source:ZFIN;Acc:ZDB-GENE-131127-263])

HSP 1 Score: 77.411 bits (189), Expect = 5.528e-15
Identity = 71/219 (32.42%), Postives = 101/219 (46.12%), Query Frame = 2

Query:  488 GAKFLADAIVKSSTIKTLKMTGNKIGDFGGMQFAQAIQINESLEELDLGECDLKISSVISFATVLLCNTTLKSLNLDRPLLWTQQEETTVHMENMLYINKSLVELHLAKYEMRDFGMERLCDALIINRTLTVLDLSCNRITRDGAKILAKVLKCNTPLKVLDLGYNRIHNQGIKAIANSLSYCNTNLKCLVITFNEIHDEGLMEITAALELNTTLDKIY 1144
            G K +  A+   + I+ L + GN I   G     Q ++ N ++E LDL    LK       A +L  N +LKS+ L    +    ++   H+ + L +N  L EL L+  E    G E L   L+ N  L VLDLS N +   GA   +  LK NT LK LDL +N   N G  AI  +L + NT +   +      + EG+  +   LE N TL   Y
Sbjct:   38 GCKAIVTAL-GDTQIRILDLAGNYIQAEGSRYLMQLLRFNSTIEHLDLSNNHLKSDGAEWVAKILSDNISLKSIKLSSRFI----DDDAKHLADALSMNSRLKELDLSHNEFCGKGGEYL-GQLLNNEGLEVLDLSWNHLRMKGAVAFSAGLKVNTMLKHLDLSWNGFGNDGALAIGEALKFNNTLVHLNLNNNRLTN-EGVSMLCRGLEYNDTLQLAY 249

HSP 2 Score: 75.8702 bits (185), Expect = 1.407e-14
Identity = 85/290 (29.31%), Postives = 133/290 (45.86%), Query Frame = 2

Query:  146 ERYVQFCN-EKNYEVSDFIRKVFNKEKI------------RLINKISDENFIYLKLCGNNKVLTKMRLTDEHIKGLCGILEEDESVKSLDLRFNRITDKGAEYIANLIKRNHSILEYNLMGNDIEEAGAKFLADAIVKSSTIKTLKMTGNKIGDFGGMQFAQAIQINESLEELDLGECDLKISSVISFATVLLCNTTLKSLNLDRPLLWTQ-QEETTVHMENMLYINKSLVELHLAKYEMRDFGMERLCDALIINRTLTVLDLSCNRITRDGAKILAKVLKCNTPLKVLD 973
            E Y+Q C  E+   VS F+R V                   ++  + D     L L GN        +  E  + L  +L  + +++ LDL  N +   GAE++A ++  N S+    L    I++  AK LADA+  +S +K L ++ N+    GG    Q +  NE LE LDL    L++   ++F+  L  NT LK L+L     W     +  + +   L  N +LV L+L    + + G+  LC  L  N T   L L+ N +T +GA +L  ++K NTP   LD
Sbjct:    1 EVYMQACRLERVIPVSHFVRNVGTATMTLNHCGLGPLGCKAIVTALGDTQIRILDLAGN-------YIQAEGSRYLMQLLRFNSTIEHLDLSNNHLKSDGAEWVAKILSDNISLKSIKLSSRFIDDD-AKHLADALSMNSRLKELDLSHNEFCGKGGEYLGQLLN-NEGLEVLDLSWNHLRMKGAVAFSAGLKVNTMLKHLDLS----WNGFGNDGALAIGEALKFNNTLVHLNLNNNRLTNEGVSMLCRGLEYNDT---LQLAYNSLTVEGALVLVNIVK-NTPKTALD 273

HSP 3 Score: 50.447 bits (119), Expect = 2.662e-6
Identity = 34/121 (28.10%), Postives = 67/121 (55.37%), Query Frame = 2

Query:  848 CDALII---NRTLTVLDLSCNRITRDGAKILAKVLKCNTPLKVLDLGYNRIHNQGIKAIANSLSYCNTNLKCLVITFNEIHDEGLMEITAALELNTTLDKIYIWGNEFTSDAIKYFGALMD 1201
            C A++    +  + +LDL+ N I  +G++ L ++L+ N+ ++ LDL  N + + G + +A  LS  N +LK + ++   I D+    +  AL +N+ L ++ +  NEF     +Y G L++
Sbjct:   39 CKAIVTALGDTQIRILDLAGNYIQAEGSRYLMQLLRFNSTIEHLDLSNNHLKSDGAEWVAKILSD-NISLKSIKLSSRFIDDDA-KHLADALSMNSRLKELDLSHNEFCGKGGEYLGQLLN 157

[Close]

BLAST of Leucine rich repeat containing 34 vs. Ensembl Medaka
Match: ppp1r37 (protein phosphatase 1 regulatory subunit 37 [Source:NCBI gene;Acc:101163101])

HSP 1 Score: 70.4774 bits (171), Expect = 2.353e-12
Identity = 83/303 (27.39%), Postives = 135/303 (44.55%), Query Frame = 2

Query:  365 KSLDLRFNRITDKGAEYIANLIKRNHSILEYNLMGND-IEEAGAKFLADAIVKSSTIKTLKMTGNKIGDFGGMQFAQAIQINESLEELDLGECDLKISSVISFATVLLCNTTLKSLNLDRPLLWTQQEETTVHMENMLYINKSLVELHLAKYEMRDFGMERLCDALIINRT-LTVLDLSCNRITRDGAKILAKVLKCNTPLKVLDLGYNRIHNQGIKA-----IANS----LSYCNTNLKC------------------LVITFNEIHDEGLMEITAALELNTTLDKIYIWGNEFTSDAIKYF 1186
            K++DL    + + GA  + ++I+   S    N+  N  I   G +  A  + K+S+++ L      + D      A+A++I+ SL  L L    L    ++  AT L  N  L+ L L    L   Q+  +  + N+L  N ++  L L    + D G+  LC+ L   R  L  L L  N++T  G   LA  L C   L+ L+LG+N + N+G+       IAN     L   +T L C                  L +  NEI   GLM ++ AL++NT+L ++ +   E   + +K F
Sbjct:  258 KTVDLEQTNLDEDGASALFDMIEYYESATHLNISFNKHIGTRGWQAAAHMMRKTSSLQYLDARNTPLLDHSAPFVARALRISGSLAVLHLENAGLSGRPLMLLATALKMNMNLRELYLADNKLNGLQD--SAQLGNLLKFNYNIQILDLRNNHILDSGLAYLCEGLKEQRKGLVTLVLWNNQLTHSGMGYLAAALPCTQSLETLNLGHNSVSNEGVHKLKDGLIANRSVLRLGLASTKLSCEGAVAVAEFIAESPRLLRLDLRENEIKTGGLMALSLALKVNTSLLRLDL-DREPKKETVKSF 557

HSP 2 Score: 49.6766 bits (117), Expect = 7.398e-6
Identity = 41/148 (27.70%), Postives = 72/148 (48.65%), Query Frame = 2

Query:  281 NNKVLTKMRLTDEHIKGLC-GILEEDESVKSLDLRFNRITDKGAEYIANLIKRNHSILEYNLMGNDIEEAGAKFLADAIVKSSTIKTLKMTGNKIGDFGGMQFAQAIQINESLEELDLGECDLKISSVISFATVLLCNTTLKSLNLDR 721
            NN +L      D  +  LC G+ E+ + + +L L  N++T  G  Y+A  +    S+   NL  N +   G   L D ++ + ++  L +   K+   G +  A+ I  +  L  LDL E ++K   +++ +  L  NT+L  L+LDR
Sbjct:  406 NNHIL------DSGLAYLCEGLKEQRKGLVTLVLWNNQLTHSGMGYLAAALPCTQSLETLNLGHNSVSNEGVHKLKDGLIANRSVLRLGLASTKLSCEGAVAVAEFIAESPRLLRLDLRENEIKTGGLMALSLALKVNTSLLRLDLDR 547

[Close]

BLAST of Leucine rich repeat containing 34 vs. Planmine SMEST
Match: SMESG000053819.1 (SMESG000053819.1)

HSP 1 Score: 714.531 bits (1843), Expect = 0.000e+0
Identity = 347/349 (99.43%), Postives = 348/349 (99.71%), Query Frame = 2

Query:  302 MRLTDEHIKGLCGILEEDESVKSLDLRFNRITDKGAEYIANLIKRNHSILEYNLMGNDIEEAGAKFLADAIVKSSTIKTLKMTGNKIGDFGGMQFAQAIQINESLEELDLGECDLKISSVISFATVLLCNTTLKSLNLDRPLLWTQQEETTVHMENMLYINKSLVELHLAKYEMRDFGMERLCDALIINRTLTVLDLSCNRITRDGAKILAKVLKCNTPLKVLDLGYNRIHNQGIKAIANSLSYCNTNLKCLVITFNEIHDEGLMEITAALELNTTLDKIYIWGNEFTSDAIKYFGALMDRFRLMESKVDVRPYSVDGIHQFALLPHNVDFRRYRYTAPIYGDDIPENR 1348
            MRLTDEHIKGLCGILEEDESVKSLDLRFNRITDKGAEYIANLIKRNHSILEYNLMGNDIEEAGAKFLADAIVKSSTIKTLKMTGNKIGDFGGMQFAQAIQINESLEELDLGECDLKISSVISFATVLLCNTTLKSLNLDRPLLWTQQEETTVHMENMLYINKSLVELHLAKYEMRDFGMERLCDALIINRTLTVLDLSCNRITRDGAKILAKVLKCNTPLKVLDLGYNRIH+QGIKAIANSL YCNTNLKCLVITFNEIHDEGLMEITAALELNTTLDKIYIWGNEFTSDAIKYFGALMDRFRLMESKVDVRPYSVDGIHQFALLPHNVDFRRYRYTAPIYGDDIPENR
Sbjct:    1 MRLTDEHIKGLCGILEEDESVKSLDLRFNRITDKGAEYIANLIKRNHSILEYNLMGNDIEEAGAKFLADAIVKSSTIKTLKMTGNKIGDFGGMQFAQAIQINESLEELDLGECDLKISSVISFATVLLCNTTLKSLNLDRPLLWTQQEETTVHMENMLYINKSLVELHLAKYEMRDFGMERLCDALIINRTLTVLDLSCNRITRDGAKILAKVLKCNTPLKVLDLGYNRIHDQGIKAIANSLCYCNTNLKCLVITFNEIHDEGLMEITAALELNTTLDKIYIWGNEFTSDAIKYFGALMDRFRLMESKVDVRPYSVDGIHQFALLPHNVDFRRYRYTAPIYGDDIPENR 349

HSP 2 Score: 54.6842 bits (130), Expect = 6.966e-8
Identity = 39/126 (30.95%), Postives = 70/126 (55.56%), Query Frame = 2

Query:  251 ENFIYLKLCGNNKVLTKMRLTDEHIKGLCGILEEDESVKSLDLRFNRITDKGAEYIANLIKRNHSILEYNLMGNDIEEAGAKFLADAIVKSST-IKTLKMTGNKIGDFGGMQFAQAIQINESLEEL 625
            EN +Y+        L K  + D  ++ LC  L  + ++  LDL  NRIT  GA+ +A ++K N  +   +L  N I + G K +A+++   +T +K L +T N+I D G M+   A+++N +L+++
Sbjct:  155 ENMLYINKSLVELHLAKYEMRDFGMERLCDALIINRTLTVLDLSCNRITRDGAKILAKVLKCNTPLKVLDLGYNRIHDQGIKAIANSLCYCNTNLKCLVITFNEIHDEGLMEITAALELNTTLDKI 280

[Close]

BLAST of Leucine rich repeat containing 34 vs. Planmine SMEST
Match: SMESG000053815.1 (SMESG000053815.1)

HSP 1 Score: 530.406 bits (1365), Expect = 0.000e+0
Identity = 262/406 (64.53%), Postives = 324/406 (79.80%), Query Frame = 2

Query:  131 FELTCERYVQFCNEKNYEVSDFIRKVFNKEKIRLINKISDENFIYLKLCGNNKVLTKMRLTDEHIKGLCGILEEDESVKSLDLRFNRITDKGAEYIANLIKRNHSILEYNLMGNDIEEAGAKFLADAIVKSSTIKTLKMTGNKIGDFGGMQFAQAIQINESLEELDLGECDLKISSVISFATVLLCNTTLKSLNLDRPLLWTQQEETTVHMENMLYINKSLVELHLAKYEMRDFGMERLCDALIINRTLTVLDLSCNRITRDGAKILAKVLKCNTPLKVLDLGYNRIHNQGIKAIANSLSYCNTNLKCLVITFNEIHDEGLMEITAALELNTTLDKIYIWGNEFTSDAIKYFGALMDRFRLMESKVDVRPYSVDGIHQFALLPHNVDFRRYRYTAPIYGDDIPENR 1348
            FELT +RY  FC E+NYE+SD IR+ F KE  R+ N  S  +FIYLK CG+N+   K +LTDE +KGLC +LEED SVKSLDLR+N I+D+GA Y+ +L+ RN +I+E NLMGNDI E GA+ ++DA+  +ST+K LK+TGNK GD+G M FA A+QIN+ LEE+DLGECDL+I SVI++ T+L CN TLKS+NLDRPLL TQQEE + H+E MLY+NK+L E+H+AKYEMRD G   +CDAL+INR+LTVLDLSCNRIT DGA  LAKVLK NTPL++LDLGYNRIH+QGI+AIA SL YCNT LKCLVI +NEI DEGL  I  AL  N+TL+KIYIWGN+FTS  I+ F +L++ FR+ E+K DVRPY VDG + FALL HN D+RRYRYTAP  G +IP+NR
Sbjct:    5 FELTSQRYEYFCYERNYEMSDCIRRYFQKEINRIKNGKSSVDFIYLKFCGDNEDFRKNKLTDEQVKGLCIVLEEDVSVKSLDLRYNLISDEGAIYLRSLLLRNRTIVELNLMGNDIGEMGAERISDALAGNSTLKILKLTGNKFGDYGAMLFASALQINDCLEEIDLGECDLEIQSVIAYTTMLECNKTLKSINLDRPLLKTQQEEFSGHIEQMLYLNKTLKEIHIAKYEMRDIGTRHICDALLINRSLTVLDLSCNRITSDGALHLAKVLKFNTPLEILDLGYNRIHDQGIQAIAGSLRYCNTRLKCLVIKYNEIEDEGLKAILTALHENSTLEKIYIWGNKFTSKFIELFVSLVN-FRISENKTDVRPYYVDGKYYFALLNHNNDYRRYRYTAPANGPEIPKNR 409

[Close]

BLAST of Leucine rich repeat containing 34 vs. Planmine SMEST
Match: SMESG000053815.1 (SMESG000053815.1)

HSP 1 Score: 504.982 bits (1299), Expect = 3.487e-178
Identity = 250/388 (64.43%), Postives = 310/388 (79.90%), Query Frame = 2

Query:  185 VSDFIRKVFNKEKIRLINKISDENFIYLKLCGNNKVLTKMRLTDEHIKGLCGILEEDESVKSLDLRFNRITDKGAEYIANLIKRNHSILEYNLMGNDIEEAGAKFLADAIVKSSTIKTLKMTGNKIGDFGGMQFAQAIQINESLEELDLGECDLKISSVISFATVLLCNTTLKSLNLDRPLLWTQQEETTVHMENMLYINKSLVELHLAKYEMRDFGMERLCDALIINRTLTVLDLSCNRITRDGAKILAKVLKCNTPLKVLDLGYNRIHNQGIKAIANSLSYCNTNLKCLVITFNEIHDEGLMEITAALELNTTLDKIYIWGNEFTSDAIKYFGALMDRFRLMESKVDVRPYSVDGIHQFALLPHNVDFRRYRYTAPIYGDDIPENR 1348
            +SD IR+ F KE  R+ N  S  +FIYLK CG+N+   K +LTDE +KGLC +LEED SVKSLDLR+N I+D+GA Y+ +L+ RN +I+E NLMGNDI E GA+ ++DA+  +ST+K LK+TGNK GD+G M FA A+QIN+ LEE+DLGECDL+I SVI++ T+L CN TLKS+NLDRPLL TQQEE + H+E MLY+NK+L E+H+AKYEMRD G   +CDAL+INR+LTVLDLSCNRIT DGA  LAKVLK NTPL++LDLGYNRIH+QGI+AIA SL YCNT LKCLVI +NEI DEGL  I  AL  N+TL+KIYIWGN+FTS  I+ F +L++ FR+ E+K DVRPY VDG + FALL HN D+RRYRYTAP  G +IP+NR
Sbjct:    1 MSDCIRRYFQKEINRIKNGKSSVDFIYLKFCGDNEDFRKNKLTDEQVKGLCIVLEEDVSVKSLDLRYNLISDEGAIYLRSLLLRNRTIVELNLMGNDIGEMGAERISDALAGNSTLKILKLTGNKFGDYGAMLFASALQINDCLEEIDLGECDLEIQSVIAYTTMLECNKTLKSINLDRPLLKTQQEEFSGHIEQMLYLNKTLKEIHIAKYEMRDIGTRHICDALLINRSLTVLDLSCNRITSDGALHLAKVLKFNTPLEILDLGYNRIHDQGIQAIAGSLRYCNTRLKCLVIKYNEIEDEGLKAILTALHENSTLEKIYIWGNKFTSKFIELFVSLVN-FRISENKTDVRPYYVDGKYYFALLNHNNDYRRYRYTAPANGPEIPKNR 387

[Close]

BLAST of Leucine rich repeat containing 34 vs. Planmine SMEST
Match: SMESG000073508.1 (SMESG000073508.1)

HSP 1 Score: 76.6406 bits (187), Expect = 6.616e-15
Identity = 74/258 (28.68%), Postives = 117/258 (45.35%), Query Frame = 2

Query:  404 GAEYIANLIKRNHSILEYNLMGNDIEEAGAKFLADAIVKSSTIKTLKMTGNKIGDFGGMQFAQAIQINESLEELDLGECDLKISSVISFATVLLCNTTLKSLNLDRPLLWTQQEETTVHMENMLYINKSLVELHLAKYEMRDFGMERLCDALIINRTLTVLDLSCNRITRDGAKILAKVLKCNTPLKVLDLGYNRIHNQGIKAIANSLSYCNTNLKCLVITFNEIHDEGLMEITAALELNTTLDKIYIWGNEFTSDAI 1177
            G + +A  ++ N S+   +L GN I   G+  +   + +++ I  L +  N IGD G + F +A+++N  L+ LD+       + +     + LC   +KS                          K L EL L++  +   G + L  A+  N  L  LDLS N+I R+GA  +AK LK N  +K  +L YN     G  A+A++L   N+ L  L I  N I  E    I  AL+ N TL ++ I  N   ++ I
Sbjct:   17 GTKALAKSLESNFSVDTLDLSGNWIYPIGSIAIGKMLEENNFISKLVLCDNMIGDQGLVGFHRALEVNRGLKHLDISG-----NQITDHGCIELCKLIVKS--------------------------KYLTELVLSRNNIDSKGAQLLATAISSNDILEYLDLSWNQIRREGAVDIAKGLKDNIRIKNCNLSYNGFAKDGGFALADTLK-DNSALIVLNIESNRIDGETAALIGKALKSNETLKELRIGNNTIDTNGI 242

HSP 2 Score: 55.4546 bits (132), Expect = 4.721e-8
Identity = 53/202 (26.24%), Postives = 95/202 (47.03%), Query Frame = 2

Query:  269 KLCGNNKVLTKMRLTDEHI--KGLCGI---LEEDESVKSLDLRFNRITDKGAEYIANLIKRNHSILEYNLMGNDIEEAGAKFLADAIVKSSTIKTLKMTGNKIGDFGGMQFAQAIQINESLEELDLGECDLKISSVISFATVLLCNTTLKSLNLDRPLLWTQQEETTVHMENMLYINKSLVELHLAKYEMRDFGMERLCDAL 859
            K+   N  ++K+ L D  I  +GL G    LE +  +K LD+  N+ITD G   +  LI ++  + E  L  N+I+  GA+ LA AI  +  ++ L ++ N+I   G +  A+ ++ N  ++  +L           + A  L  N+ L  LN++   +     ET   +   L  N++L EL +    +   G+  L  ++
Sbjct:   51 KMLEENNFISKLVLCDNMIGDQGLVGFHRALEVNRGLKHLDISGNQITDHGCIELCKLIVKSKYLTELVLSRNNIDSKGAQLLATAISSNDILEYLDLSWNQIRREGAVDIAKGLKDNIRIKNCNLSYNGFAKDGGFALADTLKDNSALIVLNIESNRI---DGETAALIGKALKSNETLKELRIGNNTIDTNGILSLMSSI 249

[Close]

BLAST of Leucine rich repeat containing 34 vs. Planmine SMEST
Match: SMESG000008282.1 (SMESG000008282.1)

HSP 1 Score: 75.485 bits (184), Expect = 2.665e-14
Identity = 84/297 (28.28%), Postives = 137/297 (46.13%), Query Frame = 2

Query:  107 KMTNIFKLFELTCERYVQFCNEKNYEVSDFIRKVFNKEKIRLINKISDENFIYLKLCGNNKVLTKMRLTDEHIKGLCGILEED-ESVKSLDLRFNRITDKGAEYIANLIKRNHSILEYNLMGNDIEEAGAKFLADAIVKSSTIKTLKMTGNKIGDFGGMQFAQAIQINESLEELDLGECDLKISSVISFATVLLCNTTLKSLNLDRPLLWTQ-QEETTVHMENMLYINKSLVELHLAKYEMRDFGMERLCDALIINRTLTVLDLSCNRITRDGAKILAKVLKCNTPLKVLDLGYNRI 991
            +++N+ +L+E  CER               +    +K  I+++ +IS  + I       N  +    LTD+   GL  I+  D     SL+L+ N I+++   Y+ + +  N  I E NL  +++ + G K L+  I+ S  IK L +  N   D  G    + +  N SL+ LDL E +       S   ++  N +L+ L+L     W Q + E  V +   L  N  L  L L      D G + L  +L+ N  L  L+++CNRIT  G   + K L+ N  LK+L +G+N I
Sbjct:   99 QLSNMCELYEGICER---------------LECPSSKRFIKILKRISAGSTI------TNIEMAHYGLTDQ---GLRAIISSDITQFSSLNLKDNIISERSLAYLISTLWTNQ-ITELNLSDSNLTKFGPKILSPWILSSKVIKNLYLRNNNFDDNDGCVLFEGVSGNRSLQLLDLAENNFSTFCGNSLKKMIEDNDSLEVLDLS----WNQLRLEGAVSLSKGLRKNNGLKRLILNWNGFEDSGTKELSQSLLENEDLEELEIACNRITDVGFANILKSLEKNVTLKILKIGWNSI 366

HSP 2 Score: 53.5286 bits (127), Expect = 2.424e-7
Identity = 50/139 (35.97%), Postives = 69/139 (49.64%), Query Frame = 2

Query:  782 NKSLVELHLAKYEMRDFGMERLCDALIINRTLTVLDLSCNRITRDGAKILAKVLKCNTPLKVLDLGYNRIHNQGIKAIANSLSYCNTNLKCLVITFNEIHDEGLMEITAALELNTTLDKIYIWGNEFTS----DAIKYF 1186
            N+SL  L LA+     F    L   +  N +L VLDLS N++  +GA  L+K L+ N  LK L L +N   + G K ++ SL     +L+ L I  N I D G   I  +LE N TL  + I  N  +     DA+K F
Sbjct:  241 NRSLQLLDLAENNFSTFCGNSLKKMIEDNDSLEVLDLSWNQLRLEGAVSLSKGLRKNNGLKRLILNWNGFEDSGTKELSQSLLEN-EDLEELEIACNRITDVGFANILKSLEKNVTLKILKIGWNSISQSAAEDALKSF 378

The following BLAST results are available for this feature:

BLAST of Leucine rich repeat containing 34 vs. Ensembl Human
BLAST of Leucine rich repeat containing 34 vs. Ensembl Celegans
BLAST of Leucine rich repeat containing 34 vs. Ensembl Fly
BLAST of Leucine rich repeat containing 34 vs. Ensembl Zebrafish
BLAST of Leucine rich repeat containing 34 vs. Ensembl Xenopus
BLAST of Leucine rich repeat containing 34 vs. Ensembl Mouse
BLAST of Leucine rich repeat containing 34 vs. UniProt/SwissProt
BLAST of Leucine rich repeat containing 34 vs. TrEMBL
BLAST of Leucine rich repeat containing 34 vs. Ensembl Cavefish
BLAST of Leucine rich repeat containing 34 vs. Ensembl Sea Lamprey
BLAST of Leucine rich repeat containing 34 vs. Ensembl Yeast
BLAST of Leucine rich repeat containing 34 vs. Ensembl Nematostella
BLAST of Leucine rich repeat containing 34 vs. Ensembl Medaka
BLAST of Leucine rich repeat containing 34 vs. Planmine SMEST

BLAST of Leucine rich repeat containing 34 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
LRRC34	1.143e-90	39.14	leucine rich repeat containing 34 [Source:HGNC Sym...	[more]
LRRC34	1.451e-89	41.74	leucine rich repeat containing 34 [Source:HGNC Sym...	[more]
LRRC34	3.777e-71	35.19	leucine rich repeat containing 34 [Source:HGNC Sym...	[more]
NLRC3	5.225e-26	26.79	NLR family CARD domain containing 3 [Source:HGNC S...	[more]
NLRC3	6.306e-26	26.79	NLR family CARD domain containing 3 [Source:HGNC S...	[more]

BLAST of Leucine rich repeat containing 34 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of Leucine rich repeat containing 34 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
CG8197	5.859e-9	21.57	gene:FBgn0033369 transcript:FBtr0339286	[more]
CG8197	5.859e-9	21.57	gene:FBgn0033369 transcript:FBtr0088661	[more]
RanGAP	4.872e-6	23.89	gene:FBgn0003346 transcript:FBtr0334175	[more]
RanGAP	5.631e-6	23.89	gene:FBgn0003346 transcript:FBtr0081234	[more]
RanGAP	5.631e-6	23.89	gene:FBgn0003346 transcript:FBtr0334174	[more]

BLAST of Leucine rich repeat containing 34 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
lrrc34	4.456e-104	44.70	leucine rich repeat containing 34 [Source:ZFIN;Acc...	[more]
lrrc34	5.097e-101	47.19	leucine rich repeat containing 34 [Source:ZFIN;Acc...	[more]
nlrc3	1.177e-26	26.73	NLR family, CARD domain containing 3 [Source:ZFIN;...	[more]
lrrc74a	9.954e-23	32.33	leucine rich repeat containing 74A [Source:ZFIN;Ac...	[more]
si:dkey-23k10.2	2.844e-17	26.55	si:dkey-23k10.2 [Source:ZFIN;Acc:ZDB-GENE-131122-5...	[more]

BLAST of Leucine rich repeat containing 34 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
lrrc34	6.464e-114	44.58	leucine rich repeat containing 34 [Source:NCBI gen...	[more]
ENSXETT00000010017.1	2.057e-17	26.88	pep primary_assembly:Xenopus_tropicalis_v9.1:1:141...	[more]
NLRC3	7.888e-16	28.83	NLR family, CARD domain containing 3 [Source:NCBI ...	[more]
NLRC3	1.266e-15	28.68	NLR family, CARD domain containing 3 [Source:NCBI ...	[more]
hcn4	1.626e-12	25.10	hyperpolarization activated cyclic nucleotide gate...	[more]

BLAST of Leucine rich repeat containing 34 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Lrrc34	4.954e-99	41.88	leucine rich repeat containing 34 [Source:MGI Symb...	[more]
Nlrc3	3.444e-26	31.29	NLR family, CARD domain containing 3 [Source:MGI S...	[more]
Nlrc3	5.349e-26	31.18	NLR family, CARD domain containing 3 [Source:MGI S...	[more]
Nlrc3	2.902e-21	30.83	NLR family, CARD domain containing 3 [Source:MGI S...	[more]
Nod1	1.050e-16	30.96	nucleotide-binding oligomerization domain containi...	[more]

BLAST of Leucine rich repeat containing 34 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q9DAM1\|LRC34_MOUSE	3.465e-98	41.88	Leucine-rich repeat-containing protein 34 OS=Mus m...	[more]
sp\|Q4V8D9\|LRC34_RAT	5.226e-95	40.25	Leucine-rich repeat-containing protein 34 OS=Rattu...	[more]
sp\|Q8IZ02\|LRC34_HUMAN	5.488e-90	39.14	Leucine-rich repeat-containing protein 34 OS=Homo ...	[more]
sp\|Q5DU56\|NLRC3_MOUSE	2.641e-25	31.29	Protein NLRC3 OS=Mus musculus OX=10090 GN=Nlrc3 PE...	[more]
sp\|Q7RTR2\|NLRC3_HUMAN	3.028e-25	26.79	NLR family CARD domain-containing protein 3 OS=Hom...	[more]

BLAST of Leucine rich repeat containing 34 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A267GWA9	3.303e-126	49.39	Uncharacterized protein (Fragment) OS=Macrostomum ...	[more]
A0A267H3H2	3.642e-126	49.39	Uncharacterized protein (Fragment) OS=Macrostomum ...	[more]
A0A267F161	5.937e-126	49.39	Uncharacterized protein (Fragment) OS=Macrostomum ...	[more]
A0A1I8I0P8	6.468e-126	49.39	Uncharacterized protein OS=Macrostomum lignano OX=...	[more]
W5MJT0	8.937e-119	48.74	Leucine rich repeat containing 34 OS=Lepisosteus o...	[more]

BLAST of Leucine rich repeat containing 34 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
lrrc34	7.147e-93	42.89	leucine rich repeat containing 34 [Source:NCBI gen...	[more]
nlrc3	1.465e-26	31.34	NLR family CARD domain containing 3 [Source:NCBI g...	[more]
nlrc3	3.228e-25	28.57	NLR family CARD domain containing 3 [Source:NCBI g...	[more]
lrrc74a	6.228e-21	32.16	leucine rich repeat containing 74A [Source:NCBI ge...	[more]
ENSAMXT00000035222.1	1.220e-18	27.25	ribonuclease inhibitor-like [Source:NCBI gene;Acc:...	[more]

BLAST of Leucine rich repeat containing 34 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5


Match Name	E-value	Identity	Description
lrrc34	2.431e-76	43.81	leucine rich repeat containing 34 [Source:ZFIN;Acc...	[more]
ENSPMAT00000002444.1	3.854e-22	29.64	pep scaffold:Pmarinus_7.0:GL480979:320698:340261:-...	[more]
lrrc74a	1.543e-13	32.30	leucine rich repeat containing 74A [Source:ZFIN;Ac...	[more]
lrrc74a	1.633e-13	32.10	leucine rich repeat containing 74A [Source:ZFIN;Ac...	[more]
ppp1r37	6.185e-11	25.36	protein phosphatase 1, regulatory subunit 37 [Sour...	[more]

BLAST of Leucine rich repeat containing 34 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of Leucine rich repeat containing 34 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5


Match Name	E-value	Identity	Description
EDO33412	3.125e-82	42.97	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO43196	4.278e-44	33.33	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO35561	1.917e-30	33.46	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO31478	5.665e-23	29.41	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO36360	9.988e-22	29.06	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of Leucine rich repeat containing 34 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
lrrc34	7.768e-72	36.73	leucine rich repeat containing 34 [Source:NCBI gen...	[more]
nlrc3	1.972e-27	30.15	NLR family CARD domain containing 3 [Source:NCBI g...	[more]
nlrc3	1.972e-27	30.15	NLR family CARD domain containing 3 [Source:NCBI g...	[more]
lrrc74a	5.528e-15	32.42	leucine rich repeat containing 74A [Source:ZFIN;Ac...	[more]
ppp1r37	2.353e-12	27.39	protein phosphatase 1 regulatory subunit 37 [Sourc...	[more]

BLAST of Leucine rich repeat containing 34 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000053819.1	6.966e-8	99.43	SMESG000053819.1	[more]
SMESG000053815.1	0.000e+0	64.53	SMESG000053815.1	[more]
SMESG000053815.1	3.487e-178	64.43	SMESG000053815.1	[more]
SMESG000073508.1	6.616e-15	28.68	SMESG000073508.1	[more]
SMESG000008282.1	2.665e-14	28.28	SMESG000008282.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30008679 ID=SMED30008679|Name=Leucine rich repeat containing 34|organism=Schmidtea mediterranea sexual|type=transcript|length=1436bp
GCACTTTATTGTTTATATAATTCGTTGCATAGTAATATTAATAGTAACTT
TTAAACTAGAATAAAATCGTAATTCGAAAATTTTTAAGTTCAAATAATTA
TTGGTAAAAATGACAAATATATTCAAGTTATTCGAACTCACATGTGAAAG
ATATGTTCAATTTTGTAATGAAAAAAACTACGAAGTATCTGACTTTATTC
GAAAAGTATTTAATAAAGAAAAAATTCGTCTTATAAATAAAATATCTGAT
GAAAACTTTATTTATTTGAAGCTTTGCGGAAACAATAAAGTGTTAACAAA
AATGAGACTAACTGATGAGCACATTAAAGGACTTTGTGGAATATTGGAAG
AAGACGAGTCTGTAAAATCACTAGACTTACGATTTAATCGAATTACGGAC
AAAGGCGCTGAGTACATTGCAAATTTAATAAAAAGAAATCATTCAATATT
AGAATATAATCTGATGGGAAACGATATCGAAGAAGCCGGCGCCAAATTTC
TGGCAGATGCGATTGTAAAAAGCTCAACGATTAAAACACTGAAAATGACC
GGTAACAAAATCGGTGATTTTGGAGGAATGCAATTCGCTCAAGCTATTCA
AATCAATGAATCTTTGGAAGAATTGGATCTTGGAGAATGTGATTTGAAAA
TAAGTAGCGTCATTTCCTTTGCTACAGTACTTCTTTGCAATACAACTCTT
AAATCTCTAAATCTCGATCGTCCTTTACTTTGGACTCAACAAGAAGAGAC
AACAGTGCACATGGAAAATATGCTTTATATAAACAAAAGTTTAGTAGAAC
TTCATTTGGCAAAGTATGAGATGCGAGATTTCGGAATGGAGCGTCTGTGT
GATGCGTTAATTATAAACCGAACTCTTACAGTTCTTGATCTTAGCTGCAA
CAGAATAACAAGAGACGGAGCGAAAATATTGGCCAAAGTGCTGAAATGCA
ACACCCCATTAAAGGTTCTTGATTTGGGATACAATAGAATCCATAACCAA
GGAATTAAGGCTATTGCTAACTCACTTAGTTATTGCAACACGAATTTGAA
ATGTTTGGTGATTACATTTAATGAAATTCATGATGAAGGTTTAATGGAAA
TTACTGCAGCGTTAGAACTGAATACTACTTTGGATAAAATATACATCTGG
GGAAATGAATTCACCTCGGATGCTATAAAGTATTTTGGGGCTTTGATGGA
TCGTTTTAGGTTAATGGAATCCAAAGTCGATGTTCGGCCTTACTCAGTTG
ATGGCATACATCAATTTGCACTACTTCCTCACAATGTAGACTTTCGCCGT
TACAGGTACACTGCCCCCATATATGGCGATGACATACCAGAGAATCGGTC
ATATGCCATCAGTTGATCATCACTGTTACTAAGGTAATCTGATCAGAAAA
GTTCAATTACTGCTTTTGAACGACCTAAGGAGATCG

protein sequence of SMED30008679-orf-1

>SMED30008679-orf-1 ID=SMED30008679-orf-1|Name=SMED30008679-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=419bp
MTNIFKLFELTCERYVQFCNEKNYEVSDFIRKVFNKEKIRLINKISDENF
IYLKLCGNNKVLTKMRLTDEHIKGLCGILEEDESVKSLDLRFNRITDKGA
EYIANLIKRNHSILEYNLMGNDIEEAGAKFLADAIVKSSTIKTLKMTGNK
IGDFGGMQFAQAIQINESLEELDLGECDLKISSVISFATVLLCNTTLKSL
NLDRPLLWTQQEETTVHMENMLYINKSLVELHLAKYEMRDFGMERLCDAL
IINRTLTVLDLSCNRITRDGAKILAKVLKCNTPLKVLDLGYNRIHNQGIK
AIANSLSYCNTNLKCLVITFNEIHDEGLMEITAALELNTTLDKIYIWGNE
FTSDAIKYFGALMDRFRLMESKVDVRPYSVDGIHQFALLPHNVDFRRYRY
TAPIYGDDIPENRSYAIS*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000016	pharynx
PLANA:0000034	epidermis
PLANA:0000418	head
PLANA:0002089	reproductive organ

Vocabulary: **INTERPRO**
Term	Definition
IPR001611	Leu-rich_rpt
IPR032675	LRR_dom_sf

Vocabulary: **molecular function**
Term	Definition
GO:0005515	protein binding
GO:0003674	molecular_function

Vocabulary: **cellular component**
Term	Definition
GO:0005575	cellular_component

Vocabulary: **biological process**
Term	Definition
GO:0008150	biological_process

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
None	No IPR available	SMART	SM00368	LRR_RI_2	coord: 110..137 e-value: 14.0 score: 9.0 coord: 225..252 e-value: 21.0 score: 7.8 coord: 166..193 e-value: 0.7 score: 18.2 coord: 138..165 e-value: 1.5 score: 15.9 coord: 338..365 e-value: 130.0 score: 2.3 coord: 82..109 e-value: 0.82 score: 17.7 coord: 281..308 e-value: 0.02 score: 24.1 coord: 253..280 e-value: 4.0E-4 score: 29.7 coord: 310..337 e-value: 50.0 score: 5.1
None	No IPR available	PANTHER	PTHR24111	FAMILY NOT NAMED	coord: 49..365
None	No IPR available	SUPERFAMILY	SSF52047	RNI-like	coord: 43..386
IPR032675	Leucine-rich repeat domain superfamily	GENE3D	G3DSA:3.80.10.10		coord: 213..375 e-value: 1.6E-34 score: 120.9
IPR032675	Leucine-rich repeat domain superfamily	GENE3D	G3DSA:3.80.10.10		coord: 37..212 e-value: 1.1E-30 score: 108.2
IPR001611	Leucine-rich repeat	PFAM	PF13516	LRR_6	coord: 281..303 e-value: 2.0E-4 score: 21.2 coord: 138..160 e-value: 0.035 score: 14.1 coord: 84..104 e-value: 2.0E-4 score: 21.1 coord: 310..331 e-value: 0.0015 score: 18.4 coord: 253..272 e-value: 4.5E-4 score: 20.1

Main menu

Leucine rich repeat containing 34

Zeng et. al., 2018

▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Davies et. al., 2017

PAGE et. al., 2020

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 9

Owlery

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