Dynein regulatory complex protein 10

Overview
NameDynein regulatory complex protein 10
Smed IDSMED30008677
Length (bp)1621
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Dynein regulatory complex protein 10 (SMED30008677) t-SNE clustered cells

Violin plots show distribution of expression levels for Dynein regulatory complex protein 10 (SMED30008677) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Dynein regulatory complex protein 10 (SMED30008677) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Dynein regulatory complex protein 10 (SMED30008677) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30008677

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 2

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
reproductive organSMED30008677SMESG000036536.1 Contig13081newmark_estsPMID:28434803
Rouhana et al., 2017		whole organism adult hermaphrodite RNA-sequencing evidence
reproductive organSMED30008677SMESG000036536.1 Contig13081uc_Smed_v2PMID:28434803
Rouhana et al., 2017		whole organism adult hermaphrodite RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Dynein regulatory complex protein 10 vs. Ensembl Human
Match: IQCD (IQ motif containing D [Source:HGNC Symbol;Acc:HGNC:25168])

HSP 1 Score: 79.7221 bits (195), Expect = 2.939e-15
Identity = 78/276 (28.26%), Postives = 147/276 (53.26%), Query Frame = 3 
Query:  657 MTPIIQFYVRSIVIAFR---NNPHAVNCVMKHKEIWQIKYNVSLIRLIELMTQLRGLLFQRLLTTPQERDEKARYLAAVCKKEKAHQIVINDLKSTLENMKIDKEKMITQMNFNIIDLQKEIYK-LEIAGXXXXXXXXXXXXXXLDEIRLAHEETKAMLTGQLNDLKVKYXXXXXXXXXXXXXXXXXKWKLETETENWINKYDSEMAEYQTQFDKLQTDYDNEKKSLQELLKIFEPLEKEYLQVLXXXXXXXXXXXXXXXXXXXLVYWATVIQSFW 1472
            ++P++Q    S     R   +NP A   +    +      +      I+ + +LRG LF++LLT+P E  +KA++L  + ++   +Q +I+ L+  L     ++   + + NF I +L+  +++ L+ +  + +   ++  +++  + R A +   A +  ++  L+ ++  LV  NR  E  +R++K+K+ETE ENWI KYD+EM E Q + + L   +  EK SL+EL +  + L  E+ Q+ EE+ I  +KR     E   +V  AT+IQ+ W
Sbjct:  141 LSPLMQQIKDSTKNVLRLLLSNPQAARLLQMQTQ----GRSAEAQNFIDSLIELRGFLFEKLLTSPMEARDKAQFLQDISRQNSNNQQIIDTLEKELAERMKNRNAEVEKENFVIQELKNHLHQVLKFSENSLVRTKQEAEKQQKADFR-ASQARVAKIQQEILQLQSQFYNLVMENREAEQALRKKKYKVETEIENWIQKYDTEMGEKQEELEDLDAVHREEKISLEELRRRHKVLVGEFAQIREEREINSKKRMEAEQEMVRMVRAATLIQALW 411
[Close]
BLAST of Dynein regulatory complex protein 10 vs. Ensembl Zebrafish
Match: iqcd (IQ motif containing D [Source:ZFIN;Acc:ZDB-GENE-060526-200])

HSP 1 Score: 75.485 bits (184), Expect = 3.206e-14
Identity = 74/273 (27.11%), Postives = 148/273 (54.21%), Query Frame = 3 
Query:  654 KMTPIIQFYVRSIVIAFRNNPHAVNCVMKHKEIWQIKYNVSLIRLIELMTQLRGLLFQRLLTTPQERDEKARYLAAVCKKEKAHQIVINDLKSTLENMKIDKEKMITQMNFNIIDLQKEIYKLEIAGXXXXXXXXXXXXXXLDEIRLAHEETKAMLTGQLNDLKVKYXXXXXXXXXXXXXXXXXKWKLETETENWINKYDSEMAEYQTQFDKLQTDYDNEKKSLQELLKIFEPLEKEYLQVLXXXXXXXXXXXXXXXXXXXLVYWATVIQSFW 1472
            K   ++Q   R I+   R  P     V+K  E       +   ++   + +LR ++ +RLLTTP E  E  + +  V ++  A+Q +I  L+  +     +K+  I+ +N  ++ L++ ++++    +  + + ++ +E++    R   +  +A L  + + L+ + N  ++ +R  E ++R+ K+K ETE EN I KYD+E+ E QT+ +++   ++ ++  L EL K F+ L+ EY Q++EE++ A+E RE +  E +     ATVIQ++W
Sbjct:  105 KSAKLVQDSFRKIIRLLRATP-TTKVVLKRIE-PNTTGEMGSQKIRNGLCELREVVLERLLTTPAEEKESRKMMLEVSQRHSANQKLIEALEKEVAEANKNKDAEISTLNNKVLQLRRTLHQMGKGLEEFVMRTQQDAEKQSHSDRKTSDGKRARLQQEASQLRTQLNNAIKASRGREQDLRKEKYKEETEIENLIQKYDAEIGEKQTELEEMTRMHEEDQMELTELEKRFDTLDLEYSQIMEERQEAQELREQQERERQIQSQAATVIQAYW 375
[Close]
BLAST of Dynein regulatory complex protein 10 vs. Ensembl Xenopus
Match: iqcd (IQ motif containing D [Source:NCBI gene;Acc:100216273])

HSP 1 Score: 86.6557 bits (213), Expect = 1.393e-17
Identity = 83/269 (30.86%), Postives = 154/269 (57.25%), Query Frame = 3 
Query:  669 IQFYVRSIVIAFRNNPHAVNCVMKHKEIWQIKYNVSLIRLIELMTQLRGLLFQRLLTTPQERDEKARYLAAVCKKEKAHQIVINDLKSTLENMKIDKEKMITQMNFNIIDLQKEIYKLE-IAGXXXXXXXXXXXXXXLDEIRLAHEETKAMLTGQLNDLKVKYXXXXXXXXXXXXXXXXXKWKLETETENWINKYDSEMAEYQTQFDKLQTDYDNEKKSLQELLKIFEPLEKEYLQVLXXXXXXXXXXXXXXXXXXXLVYWATVIQSFW 1472
            IQ  +R+ +  F +NP A   +     +    Y      LI+ M+++RG LF+ LLT+P E+ EK RYL  +  + K ++ ++  L+  L+ + +D++  I++ N  I  L+  +++LE ++       +++   ++  + R + E   + +  +L  L+ + +  +  NR  EL +R++K+K+ETE ENWI KYD++M E Q + ++L+ +Y+ EK  L E+ +    +E+EY+Q++EE+R+AK + E E  E       ATVIQ+ W
Sbjct:  144 IQSSIRNTLRLFVSNPPASKALRAEGHLRDPAYQ----ELIQTMSEMRGFLFEFLLTSPLEQTEKMRYLHDITIRNKKNRELLLTLEEELKTVVLDRDTEISKKNEIIRHLKVNLHQLEKLSESQVKRIMQEAETQQKSDCRTS-EGKCSKIHHELQQLRSQLSSTISENREIELTMRKKKYKIETEIENWIQKYDTDMGEKQDELEELEAEYNLEKAQLAEVQEKLAVMEEEYIQIMEERRLAKLRMEEEERELANKNRAATVIQAHW 407
[Close]
BLAST of Dynein regulatory complex protein 10 vs. Ensembl Mouse
Match: Iqcd (IQ motif containing D [Source:MGI Symbol;Acc:MGI:1922982])

HSP 1 Score: 88.1965 bits (217), Expect = 3.724e-18
Identity = 74/235 (31.49%), Postives = 135/235 (57.45%), Query Frame = 3 
Query:  786 LIELMTQLRGLLFQRLLTTPQERDEKARYLAAVCKKEKAHQIVINDLKSTLENMKIDKEKMITQMNFNIIDLQKEIYKL------EIAGXXXXXXXXXXXXXXLDEIRLAHEETKAMLTGQLNDLKVKYXXXXXXXXXXXXXXXXXKWKLETETENWINKYDSEMAEYQTQFDKLQTDYDNEKKSLQELLKIFEPLEKEYLQVLXXXXXXXXXXXXXXXXXXXLVYWATVIQSFW 1472
            L++ + +LRG LF++LLT+P E  EK +++  + ++ + +Q VI+DL++ L N+  +KE  + + NF I +L+  ++++       +    +  + ++K +    ++RLA  +   +       L+ +Y+ LV  NR  E  +R++K+K+ETE ENWI KYD EM E Q +++ L++ +  EK  L+EL +    L +E+ Q+  E  I  +KR     E   +V  AT+IQ+ W
Sbjct:  180 LLDGLVELRGFLFEKLLTSPMEVREKNQFIQDISRRSERNQEVIDDLQAELANVLKNKESEVEKENFVIQELKNHLHQVFKFSENSLLRTKQEAEKQQKVDFRASQVRLAKTQQDILA------LRAQYHNLVMENREAEQALRKKKYKVETEIENWIQKYDMEMGEKQDEYEDLESIHKEEKLQLEELRERHAVLVEEFSQIRAESEINSKKRVEAEREMVRMVRAATLIQAVW 408
[Close]
BLAST of Dynein regulatory complex protein 10 vs. Ensembl Mouse
Match: Iqcd (IQ motif containing D [Source:MGI Symbol;Acc:MGI:1922982])

HSP 1 Score: 81.2629 bits (199), Expect = 5.618e-16
Identity = 66/229 (28.82%), Postives = 116/229 (50.66%), Query Frame = 3 
Query:  786 LIELMTQLRGLLFQRLLTTPQERDEKARYLAAVCKKEKAHQIVINDLKSTLENMKIDKEKMITQMNFNIIDLQKEIYKLEIAGXXXXXXXXXXXXXXLDEIRLAHEETKAMLTGQLNDLKVKYXXXXXXXXXXXXXXXXXKWKLETETENWINKYDSEMAEYQTQFDKLQTDYDNEKKSLQELLKIFEPLEKEYLQVLXXXXXXXXXXXXXXXXXXXLVYWATVIQSFW 1472
            L++ + +LRG LF++LLT+P E  EK +++  + ++ + +Q VI+DL++ L N+  +KE  + + NF I +L+  ++++                           E   + T Q  + + K +    +           K+K+ETE ENWI KYD EM E Q +++ L++ +  EK  L+EL +    L +E+ Q+  E  I  +KR     E   +V  AT+IQ+ W
Sbjct:  180 LLDGLVELRGFLFEKLLTSPMEVREKNQFIQDISRRSERNQEVIDDLQAELANVLKNKESEVEKENFVIQELKNHLHQV-----------------------FKFSENSLLRTKQEAEKQQKVDFRASQK----------KYKVETEIENWIQKYDMEMGEKQDEYEDLESIHKEEKLQLEELRERHAVLVEEFSQIRAESEINSKKRVEAEREMVRMVRAATLIQAVW 375
[Close]
BLAST of Dynein regulatory complex protein 10 vs. UniProt/SwissProt
Match: sp|Q9D3V1|DRC10_MOUSE (Dynein regulatory complex protein 10 OS=Mus musculus OX=10090 GN=Iqcd PE=2 SV=1)

HSP 1 Score: 88.1965 bits (217), Expect = 2.605e-17
Identity = 74/235 (31.49%), Postives = 135/235 (57.45%), Query Frame = 3 
Query:  786 LIELMTQLRGLLFQRLLTTPQERDEKARYLAAVCKKEKAHQIVINDLKSTLENMKIDKEKMITQMNFNIIDLQKEIYKL------EIAGXXXXXXXXXXXXXXLDEIRLAHEETKAMLTGQLNDLKVKYXXXXXXXXXXXXXXXXXKWKLETETENWINKYDSEMAEYQTQFDKLQTDYDNEKKSLQELLKIFEPLEKEYLQVLXXXXXXXXXXXXXXXXXXXLVYWATVIQSFW 1472
            L++ + +LRG LF++LLT+P E  EK +++  + ++ + +Q VI+DL++ L N+  +KE  + + NF I +L+  ++++       +    +  + ++K +    ++RLA  +   +       L+ +Y+ LV  NR  E  +R++K+K+ETE ENWI KYD EM E Q +++ L++ +  EK  L+EL +    L +E+ Q+  E  I  +KR     E   +V  AT+IQ+ W
Sbjct:  180 LLDGLVELRGFLFEKLLTSPMEVREKNQFIQDISRRSERNQEVIDDLQAELANVLKNKESEVEKENFVIQELKNHLHQVFKFSENSLLRTKQEAEKQQKVDFRASQVRLAKTQQDILA------LRAQYHNLVMENREAEQALRKKKYKVETEIENWIQKYDMEMGEKQDEYEDLESIHKEEKLQLEELRERHAVLVEEFSQIRAESEINSKKRVEAEREMVRMVRAATLIQAVW 408
[Close]
BLAST of Dynein regulatory complex protein 10 vs. UniProt/SwissProt
Match: sp|Q5XIR6|DRC10_RAT (Dynein regulatory complex protein 10 OS=Rattus norvegicus OX=10116 GN=Iqcd PE=2 SV=2)

HSP 1 Score: 80.1073 bits (196), Expect = 9.613e-15
Identity = 73/229 (31.88%), Postives = 134/229 (58.52%), Query Frame = 3 
Query:  786 LIELMTQLRGLLFQRLLTTPQERDEKARYLAAVCKKEKAHQIVINDLKSTLENMKIDKEKMITQMNFNIIDLQKEIYKLEIAGXXXXXXXXXXXXXXLDEIRLAHEETKAMLTGQLNDLKVKYXXXXXXXXXXXXXXXXXKWKLETETENWINKYDSEMAEYQTQFDKLQTDYDNEKKSLQELLKIFEPLEKEYLQVLXXXXXXXXXXXXXXXXXXXLVYWATVIQSFW 1472
            L+  + +LRG LF++LLT+P E  EK +++  + ++ K +Q +I+ L++ L  +  +KE  + + NF I +L+  ++++    +N + + ++++E++      A +  +A     +  L+ +Y+ LV  NR  E  +R++K+K+ETE ENWI KYD EM E Q +++ L+T +  EK  L+EL +    L +E+ Q+  E  I  +KR     E   +V  AT+IQ+ W
Sbjct:  180 LLTSLVELRGFLFEKLLTSPMEVREKNQFIQDISRRSKRNQEIIDALQAELAEVLKNKEAEVEKENFVIQELKNHLHQVFKFSENSLLRTKQEAEKQQKVDYRASQARQAKTQQDILALRAQYHNLVMENREAEQALRKKKYKVETEIENWIQKYDMEMNEKQEEYEDLETIHKEEKLQLEELKERHAVLVEEFSQIRAESEINSKKRVEAEREMVRMVRAATLIQAMW 408
[Close]
BLAST of Dynein regulatory complex protein 10 vs. UniProt/SwissProt
Match: sp|Q96DY2|DRC10_HUMAN (Dynein regulatory complex protein 10 OS=Homo sapiens OX=9606 GN=IQCD PE=1 SV=2)

HSP 1 Score: 79.7221 bits (195), Expect = 1.411e-14
Identity = 78/276 (28.26%), Postives = 147/276 (53.26%), Query Frame = 3 
Query:  657 MTPIIQFYVRSIVIAFR---NNPHAVNCVMKHKEIWQIKYNVSLIRLIELMTQLRGLLFQRLLTTPQERDEKARYLAAVCKKEKAHQIVINDLKSTLENMKIDKEKMITQMNFNIIDLQKEIYK-LEIAGXXXXXXXXXXXXXXLDEIRLAHEETKAMLTGQLNDLKVKYXXXXXXXXXXXXXXXXXKWKLETETENWINKYDSEMAEYQTQFDKLQTDYDNEKKSLQELLKIFEPLEKEYLQVLXXXXXXXXXXXXXXXXXXXLVYWATVIQSFW 1472
            ++P++Q    S     R   +NP A   +    +      +      I+ + +LRG LF++LLT+P E  +KA++L  + ++   +Q +I+ L+  L     ++   + + NF I +L+  +++ L+ +  + +   ++  +++  + R A +   A +  ++  L+ ++  LV  NR  E  +R++K+K+ETE ENWI KYD+EM E Q + + L   +  EK SL+EL +  + L  E+ Q+ EE+ I  +KR     E   +V  AT+IQ+ W
Sbjct:  141 LSPLMQQIKDSTKNVLRLLLSNPQAARLLQMQTQ----GRSAEAQNFIDSLIELRGFLFEKLLTSPMEARDKAQFLQDISRQNSNNQQIIDTLEKELAERMKNRNAEVEKENFVIQELKNHLHQVLKFSENSLVRTKQEAEKQQKADFR-ASQARVAKIQQEILQLQSQFYNLVMENREAEQALRKKKYKVETEIENWIQKYDTEMGEKQEELEDLDAVHREEKISLEELRRRHKVLVGEFAQIREEREINSKKRMEAEQEMVRMVRAATLIQALW 411
[Close]
BLAST of Dynein regulatory complex protein 10 vs. UniProt/SwissProt
Match: sp|Q4R8Y5|DRC10_MACFA (Dynein regulatory complex protein 10 OS=Macaca fascicularis OX=9541 GN=IQCD PE=2 SV=1)

HSP 1 Score: 78.5666 bits (192), Expect = 2.675e-14
Identity = 69/229 (30.13%), Postives = 136/229 (59.39%), Query Frame = 3 
Query:  789 IELMTQLRGLLFQRLLTTPQERDEKARYLAAVCKKEKAHQIVINDLKSTLENMKIDKEKMITQMNFNIIDLQKEIYK-LEIAGXXXXXXXXXXXXXXLDEIRLAHEETKAMLTGQLNDLKVKYXXXXXXXXXXXXXXXXXKWKLETETENWINKYDSEMAEYQTQFDKLQTDYDNEKKSLQELLKIFEPLEKEYLQVLXXXXXXXXXXXXXXXXXXXLVYWATVIQSFW 1472
            I+ + +LRG LF++L+T+P E  +KA+++  + ++   +Q +I+ L++ L      +   + + NF I +L+  +++ L+ +  + +   ++  +++  + R A +   A +  ++  L+ ++  LV  NR  E  +R++K+K+ETE ENWI KYD+EM E Q + + L+  +  EK +L+EL +  + L +E++Q+ EE+ I  +KR     E   +V  AT+IQ+FW
Sbjct:  161 IDSLIELRGFLFEKLVTSPMEARDKAQFIQDINRQNSNNQQIIDTLENELAERMKKRNAEVEKENFVIQELKNHLHQVLKFSENSLLRTKQEAEKQQKADFR-ASQARVAKIQQEILQLQSQFYNLVMENREAEQALRKKKYKVETEIENWIQKYDTEMGEKQEELEDLEAVHKEEKIALEELKRRHKVLVEEFVQIREEREINSKKRMEAEQEMVRMVRAATLIQAFW 388
[Close]
BLAST of Dynein regulatory complex protein 10 vs. UniProt/SwissProt
Match: sp|Q17QH9|DRC10_BOVIN (Dynein regulatory complex protein 10 OS=Bos taurus OX=9913 GN=IQCD PE=2 SV=1)

HSP 1 Score: 78.5666 bits (192), Expect = 3.685e-14
Identity = 69/230 (30.00%), Postives = 136/230 (59.13%), Query Frame = 3 
Query:  786 LIELMTQLRGLLFQRLLTTPQERDEKARYLAAVCKKEKAHQIVINDLKSTLENMKIDKEKMITQMNFNIIDLQKEIYK-LEIAGXXXXXXXXXXXXXXLDEIRLAHEETKAMLTGQLNDLKVKYXXXXXXXXXXXXXXXXXKWKLETETENWINKYDSEMAEYQTQFDKLQTDYDNEKKSLQELLKIFEPLEKEYLQVLXXXXXXXXXXXXXXXXXXXLVYWATVIQSFW 1472
             I+ + +LRG LF++LLT+P E  +K +++  + ++ + HQ +I+ L++ L     ++   + + NF I +L+  +++ L  +  + +   ++  +++  + R A +   A +  ++  L+ ++  LV  NR+ E  +R++K+K+ETE ENWI KYDSEM+E Q ++++L   +  E+  L+EL K  + L +E+ Q+  E+ I  +KR  +  E   +V  AT+IQ+ W
Sbjct:  183 FIDSLVELRGFLFEKLLTSPMEARDKIQFIQDITRRNRRHQEIIDTLENELAACVRNRNAEVEKENFVIQELKNHLHQVLRFSENSLLRTKQEAEKQQKADFR-ASQARVATVQQEILVLQSQFYNLVMENRDTEQALRKKKYKVETEIENWIQKYDSEMSEKQDEYEELDIIHKEEQLQLEELKKRHDVLVEEFSQIQAEREILTKKRLEDEQEMVRMVRAATLIQALW 411
[Close]
BLAST of Dynein regulatory complex protein 10 vs. TrEMBL
Match: A0A1I8HTE4 (Uncharacterized protein OS=Macrostomum lignano OX=282301 PE=4 SV=1)

HSP 1 Score: 115.931 bits (289), Expect = 4.984e-24
Identity = 95/270 (35.19%), Postives = 157/270 (58.15%), Query Frame = 3 
Query:  663 PIIQFYVRSIVIAFRNNPHAVNCVMKHKEIWQIKYNVSLIRLIELMTQLRGLLFQRLLTTPQERDEKARYLAAVCKKEKAHQIVINDLKSTLENMKIDKEKMITQMNFNIIDLQKEIYKLEIAGXXXXXXXXXXXXXXLDEIRLAHEETKAMLTGQLNDLKVKYXXXXXXXXXXXXXXXXXKWKLETETENWINKYDSEMAEYQTQFDKLQTDYDNEKKSLQELLKIFEPLEKEYLQVLXXXXXXXXXXXXXXXXXXXLVYWATVIQSFW 1472
            P +QF  R ++ AFR+NP AV  V++     ++K       +++ M  LR ++  RL+TTP E+ +K  YL  + ++E+    VI  L++ L     DKE  + + N  I  +Q +I+ +E   +  I  I  ++E++        E     LT + N L+ + + L+  +R++E ++R +K+KLETE EN I+KYDSEM   Q +++ +   Y  EKK L EL + F+ LE+EYLQ++EE+R+A+E+R A   E + ++  AT IQSFW
Sbjct:  170 PRLQFSARVLLRAFRSNPPAVTAVLQS---AKLKPQTETKEMLDRMEHLRDIMVVRLMTTPVEKQDKLTYLHEMSERERQQAEVIKKLEAELSAATADKEAEVKKKNDVIRKIQSDIHHVEKYAEESIKNIRSEAEKQQQTDSKNSEGKVHKLTQERNQLRTQLDNLIAEHRDSEQQLRSKKFKLETEIENIISKYDSEMGTRQEEYEDVDAAYTEEKKQLSELEERFKTLEEEYLQIMEERRVAEERRRAAEHEMQMMISAATTIQSFW 436
[Close]
BLAST of Dynein regulatory complex protein 10 vs. TrEMBL
Match: A0A267EP97 (Uncharacterized protein (Fragment) OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig027354g1 PE=4 SV=1)

HSP 1 Score: 115.931 bits (289), Expect = 5.269e-24
Identity = 95/270 (35.19%), Postives = 157/270 (58.15%), Query Frame = 3 
Query:  663 PIIQFYVRSIVIAFRNNPHAVNCVMKHKEIWQIKYNVSLIRLIELMTQLRGLLFQRLLTTPQERDEKARYLAAVCKKEKAHQIVINDLKSTLENMKIDKEKMITQMNFNIIDLQKEIYKLEIAGXXXXXXXXXXXXXXLDEIRLAHEETKAMLTGQLNDLKVKYXXXXXXXXXXXXXXXXXKWKLETETENWINKYDSEMAEYQTQFDKLQTDYDNEKKSLQELLKIFEPLEKEYLQVLXXXXXXXXXXXXXXXXXXXLVYWATVIQSFW 1472
            P +QF  R ++ AFR+NP AV  V++     ++K       +++ M  LR ++  RL+TTP E+ +K  YL  + ++E+    VI  L++ L     DKE  + + N  I  +Q +I+ +E   +  I  I  ++E++        E     LT + N L+ + + L+  +R++E ++R +K+KLETE EN I+KYDSEM   Q +++ +   Y  EKK L EL + F+ LE+EYLQ++EE+R+A+E+R A   E + ++  AT IQSFW
Sbjct:  181 PRLQFSARVLLRAFRSNPPAVTAVLQS---AKLKPQTETKEMLDRMEHLRDIMVVRLMTTPVEKQDKLTYLHEMSERERQQAEVIKKLEAELSAATADKEAEVKKKNDVIRKIQSDIHHVEKYAEESIKNIRSEAEKQQQTDSKNSEGKVHKLTQERNQLRTQLDNLIAEHRDSEQQLRSKKFKLETEIENIISKYDSEMGTRQEEYEDVDAAYTEEKKQLSELEERFKTLEEEYLQIMEERRVAEERRRAAEHEMQMMISAATTIQSFW 447
[Close]
BLAST of Dynein regulatory complex protein 10 vs. TrEMBL
Match: A0A1I8IRL0 (Uncharacterized protein OS=Macrostomum lignano OX=282301 PE=4 SV=1)

HSP 1 Score: 115.931 bits (289), Expect = 5.698e-24
Identity = 95/270 (35.19%), Postives = 157/270 (58.15%), Query Frame = 3 
Query:  663 PIIQFYVRSIVIAFRNNPHAVNCVMKHKEIWQIKYNVSLIRLIELMTQLRGLLFQRLLTTPQERDEKARYLAAVCKKEKAHQIVINDLKSTLENMKIDKEKMITQMNFNIIDLQKEIYKLEIAGXXXXXXXXXXXXXXLDEIRLAHEETKAMLTGQLNDLKVKYXXXXXXXXXXXXXXXXXKWKLETETENWINKYDSEMAEYQTQFDKLQTDYDNEKKSLQELLKIFEPLEKEYLQVLXXXXXXXXXXXXXXXXXXXLVYWATVIQSFW 1472
            P +QF  R ++ AFR+NP AV  V++     ++K       +++ M  LR ++  RL+TTP E+ +K  YL  + ++E+    VI  L++ L     DKE  + + N  I  +Q +I+ +E   +  I  I  ++E++        E     LT + N L+ + + L+  +R++E ++R +K+KLETE EN I+KYDSEM   Q +++ +   Y  EKK L EL + F+ LE+EYLQ++EE+R+A+E+R A   E + ++  AT IQSFW
Sbjct:  170 PRLQFSARVLLRAFRSNPPAVTAVLQS---AKLKPQTETKEMLDRMEHLRDIMVVRLMTTPVEKQDKLTYLHEMSERERQQAEVIKKLEAELSAATADKEAEVKKKNDVIRKIQSDIHHVEKYAEESIKNIRSEAEKQQQTDSKNSEGKVHKLTQERNQLRTQLDNLIAEHRDSEQQLRSKKFKLETEIENIISKYDSEMGTRQEEYEDVDAAYTEEKKQLSELEERFKTLEEEYLQIMEERRVAEERRRAAEHEMQMMISAATTIQSFW 436
[Close]
BLAST of Dynein regulatory complex protein 10 vs. TrEMBL
Match: A0A2B4SS11 (IQ domain-containing protein D OS=Stylophora pistillata OX=50429 GN=Iqcd PE=4 SV=1)

HSP 1 Score: 114.775 bits (286), Expect = 1.699e-23
Identity = 97/269 (36.06%), Postives = 153/269 (56.88%), Query Frame = 3 
Query:  669 IQFYVRSIVIAFRNNPHAVNCVMKHKEIWQIKYNVSLIRLIELMTQLRGLLFQRLLTTPQERDEKARYLAAVCKKEKAHQIVINDLKSTLENMKIDKEKMITQMNFNIIDLQKEIYKLEIAGXXXXXXXXXXXXXXLDEIRLAHEETK-AMLTGQLNDLKVKYXXXXXXXXXXXXXXXXXKWKLETETENWINKYDSEMAEYQTQFDKLQTDYDNEKKSLQELLKIFEPLEKEYLQVLXXXXXXXXXXXXXXXXXXXLVYWATVIQSFW 1472
            +++ V++I+  F +NP AVN +   +    ++ N    ++I+ MT LR +LF+RLLTTP E  E+ +YL  +  +E         L+  L+    DKE  I++ N  I+ L+ +IY +E     E  +       + D   + + ++K + L  +  +LK K       +R +EL +R+RK+K+ETE ENWI KYD++M E Q +FD L T Y  EK+ L EL + F+ LEKEY++++E +RIAKEK EA   E    +  A +IQS W
Sbjct:  203 MKYSVKTILRLFASNPAAVNALKDLRNERSVEGN----KIIDEMTTLRAVLFERLLTTPSEEKERRQYLKQIVAREMKSSETGRKLQDELKRAIDDKENEISKRNDIILRLKNDIYNVE-KNAEEQNRRVITEAAKQDASEMKNSDSKKSKLQQESIELKKKLESDTLTHRESELALRKRKYKIETEVENWIQKYDTDMGERQDEFDALDTIYTEEKRQLNELEERFKTLEKEYVEIVEARRIAKEKAEAAERELNLKIRAARLIQSLW 466
[Close]
BLAST of Dynein regulatory complex protein 10 vs. TrEMBL
Match: A0A3M6V012 (Uncharacterized protein OS=Pocillopora damicornis OX=46731 GN=pdam_00005702 PE=4 SV=1)

HSP 1 Score: 114.39 bits (285), Expect = 2.730e-23
Identity = 98/269 (36.43%), Postives = 151/269 (56.13%), Query Frame = 3 
Query:  669 IQFYVRSIVIAFRNNPHAVNCVMKHKEIWQIKYNVSLIRLIELMTQLRGLLFQRLLTTPQERDEKARYLAAVCKKEKAHQIVINDLKSTLENMKIDKEKMITQMNFNIIDLQKEIYKLEIAGXXXXXXXXXXXXXXLDEIRLAHEETK-AMLTGQLNDLKVKYXXXXXXXXXXXXXXXXXKWKLETETENWINKYDSEMAEYQTQFDKLQTDYDNEKKSLQELLKIFEPLEKEYLQVLXXXXXXXXXXXXXXXXXXXLVYWATVIQSFW 1472
            +++ V++I+  F +NP AVN +   +    ++ N     +I+ MT LR +LF+RLLTTP E  E+ +YL  +  +E         L+  L+    DKE  I++ N  I  L+ +IY +E     E  +       + D   + + ++K + L  +  +LK K       +R +EL +R+RK+K+ETE ENWI KYD++M E Q +FD L T Y  EK+ L EL + F+ LEKEYL+++E +RIAKEK EA   E    +  A +IQS W
Sbjct:  203 MKYSVKTILRLFASNPAAVNALKDLRNERSVEGNT----MIDEMTTLRAILFERLLTTPSEEKERKQYLKQIIAREMKSSETGRKLQDELKRAIDDKENEISKRNDIIRRLKNDIYNVE-KNAEEQNRRVITEAAKQDASEMKNSDSKKSKLQQESIELKKKLESDTLTHRESELALRKRKYKIETEVENWIQKYDTDMGERQDEFDALDTIYTEEKRQLNELEERFKTLEKEYLEIVEARRIAKEKAEAAERELNLKIRAARLIQSLW 466
[Close]
BLAST of Dynein regulatory complex protein 10 vs. Ensembl Cavefish
Match: iqcd (IQ motif containing D [Source:NCBI gene;Acc:103032804])

HSP 1 Score: 56.9954 bits (136), Expect = 2.306e-8
Identity = 68/221 (30.77%), Postives = 123/221 (55.66%), Query Frame = 3 
Query:  810 RGLLFQRLLTTPQERDEKARYLAAVCKKEKAHQIVINDLKSTLENMKIDKEKMITQMNFNIIDLQKEIYKLEIAGXXXXXXXXXXXXXXLDEIRLAHEETKAMLTGQLNDLKVKYXXXXXXXXXXXXXXXXXKWKLETETENWINKYDSEMAEYQTQFDKLQTDYDNEKKSLQELLKIFEPLEKEYLQVLXXXXXXXXXXXXXXXXXXXLVYWATVIQSFW 1472
            R +L +RL  TP E   + + +     +  ++Q V+  L+        D++K I+ MN  I  L+  I K E    + + + +K++E   + ++   E  +  L  ++N LKV+   L+ ++R+ EL +R++ +K+ETE +NWI KYD+EM E QT+ +++   ++ E   L EL + +   E E+ +++EE RI +E+R+ E  E E     A +IQ+FW
Sbjct:  160 RVVLLKRLFMTPMEERVRIQRMQEDTLRHNSNQKVLATLEKEAAAAVKDRDKEISWMNKVIQWLRSSILKTEKCSDDFVVRKQKEAERHDESVQKTSELKQTRLQEEVNQLKVQLKNLIIQHRDAELALRKKSYKVETEVQNWIEKYDAEMGEKQTKLEEITQIHEEEMAELSELQEYYAVRELEFSKIMEEHRIEQERRDEEEREREVQSRAAIIIQAFW 380
[Close]
BLAST of Dynein regulatory complex protein 10 vs. Ensembl Cavefish
Match: iqcd (IQ motif containing D [Source:NCBI gene;Acc:103032804])

HSP 1 Score: 56.9954 bits (136), Expect = 2.306e-8
Identity = 68/221 (30.77%), Postives = 123/221 (55.66%), Query Frame = 3 
Query:  810 RGLLFQRLLTTPQERDEKARYLAAVCKKEKAHQIVINDLKSTLENMKIDKEKMITQMNFNIIDLQKEIYKLEIAGXXXXXXXXXXXXXXLDEIRLAHEETKAMLTGQLNDLKVKYXXXXXXXXXXXXXXXXXKWKLETETENWINKYDSEMAEYQTQFDKLQTDYDNEKKSLQELLKIFEPLEKEYLQVLXXXXXXXXXXXXXXXXXXXLVYWATVIQSFW 1472
            R +L +RL  TP E   + + +     +  ++Q V+  L+        D++K I+ MN  I  L+  I K E    + + + +K++E   + ++   E  +  L  ++N LKV+   L+ ++R+ EL +R++ +K+ETE +NWI KYD+EM E QT+ +++   ++ E   L EL + +   E E+ +++EE RI +E+R+ E  E E     A +IQ+FW
Sbjct:  160 RVVLLKRLFMTPMEERVRIQRMQEDTLRHNSNQKVLATLEKEAAAAVKDRDKEISWMNKVIQWLRSSILKTEKCSDDFVVRKQKEAERHDESVQKTSELKQTRLQEEVNQLKVQLKNLIIQHRDAELALRKKSYKVETEVQNWIEKYDAEMGEKQTKLEEITQIHEEEMAELSELQEYYAVRELEFSKIMEEHRIEQERRDEEEREREVQSRAAIIIQAFW 380
[Close]
BLAST of Dynein regulatory complex protein 10 vs. Ensembl Nematostella
Match: EDO44929 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RUM4])

HSP 1 Score: 106.686 bits (265), Expect = 4.106e-25
Identity = 92/273 (33.70%), Postives = 154/273 (56.41%), Query Frame = 3 
Query:  657 MTPIIQFYVRSIVIAFRNNPHAVNCVMKHKEIWQIKYNVSLIRLIELMTQLRGLLFQRLLTTPQERDEKARYLAAVCKKEKAHQIVINDLKSTLENMKIDKEKMITQMNFNIIDLQKEIYKLEIAGXXXXXXXXXXXXXXLDEIRLAHEETK-AMLTGQLNDLKVKYXXXXXXXXXXXXXXXXXKWKLETETENWINKYDSEMAEYQTQFDKLQTDYDNEKKSLQELLKIFEPLEKEYLQVLXXXXXXXXXXXXXXXXXXXLVYWATVIQSFW 1472
            ++ ++Q  +R+++  F  NP A+  +   +     + N     +I+ ++ +R +LF+RLLTTP E  ++ +YL AV +++K    + + L+  L+N   D++  I + N  I  L+ +I+ ++     E  K       + D   + + + K A L  +L + K K       +R +EL +R+RK+K+ETE ENWI K+D++M E Q +FD L   Y  EKK LQEL + F+ LE EY+Q++EE+RIAKEK EA   E    +  A +IQ+ W
Sbjct:   98 LSMMLQQSLRTLLRQFSRNPTAMTAIRTERHERSFESNS----MIDELSAIRAVLFERLLTTPSELKDRDKYLMAVAERQKRSSQMADKLQDELQNAIDDRDNEIAKRNEIIRRLKNDIFNVD-KNAEEQNKRIVTEASKQDAAEMKNSDGKKAKLQQELIETKKKLEAQTAAHRESELALRKRKYKIETEVENWIQKFDNDMGERQDEFDALDVVYTEEKKQLQELEERFKTLEAEYVQIVEERRIAKEKAEAAERELNLKIRAARLIQAMW 365
[Close]
BLAST of Dynein regulatory complex protein 10 vs. Ensembl Nematostella
Match: EDO49121 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RGV7])

HSP 1 Score: 61.2326 bits (147), Expect = 3.710e-10
Identity = 74/270 (27.41%), Postives = 133/270 (49.26%), Query Frame = 3 
Query:  669 IQFYVRSIVIAFRNNPHAVNCVMKHKEIWQIKYNVSLIRLIELMTQLRGLLFQRLLTTPQERDEKARYLAAVCKKEKAHQIVINDLKSTLENMKIDKEKMITQMNFNIIDLQKEIYKL-EIAGXXXXXXXXXXXXXXLDEIRLAHEETKAMLTGQLNDLKVKYXXXXXXXXXXXXXXXXXK-WKLETETENWINKYDSEMAEYQTQFDKLQTDYDNEKKSLQELLKIFEPLEKEYLQVLXXXXXXXXXXXXXXXXXXXLVYWATVIQSFW 1472
            ++F +  I+  F+ NP AV  ++  K     K +     L++ MTQL  ++ +RLLTTP E  ++  Y+  +  +E+        L++       DKE  +++ N  I  L+ E+  +  +  + +   +   +++   EI+ +  E K M   +    K K+     R    E  + R++ +K+ TE  NWI KYD++M   Q    KL   Y+ EK+ L+E+ + F+ +E +Y  +LEE+R+A E  +  + E     Y A  IQ+ W
Sbjct:  100 LKFSLMDILRHFKKNPKAVEVILGSKH----KTDPVHQELLQFMTQLSMVMKERLLTTPTEEFDRKGYIVDILTRERKTNAAKGRLQARCREAVRDKEHEVSKRNTIIAQLKSELSMINNVTHEAQRKTLSDAAKQCSTEIKTS--ENKKMTIREDMITKRKHVRDRRREHREEETVLRKRAFKIGTEVYNWIQKYDADMGAKQA-IAKL---YEEEKQDLREMEQEFQNMEAKYNAILEERRLAAEAEKKRQQELVQRNYAAVRIQAVW 359
[Close]
BLAST of Dynein regulatory complex protein 10 vs. Planmine SMEST
Match: SMESG000036536.1 (SMESG000036536.1)

HSP 1 Score: 331.643 bits (849), Expect = 0.000e+0
Identity = 222/227 (97.80%), Postives = 225/227 (99.12%), Query Frame = 3 
Query:  792 ELMTQLRGLLFQRLLTTPQERDEKARYLAAVCKKEKAHQIVINDLKSTLENMKIDKEKMITQMNFNIIDLQKEIYKLEIAGXXXXXXXXXXXXXXLDEIRLAHEETKAMLTGQLNDLKVKYXXXXXXXXXXXXXXXXXKWKLETETENWINKYDSEMAEYQTQFDKLQTDYDNEKKSLQELLKIFEPLEKEYLQVLXXXXXXXXXXXXXXXXXXXLVYWATVIQSFW 1472
            ++  +LRGLLFQRLLTTPQERDEKARYLAAVCKKEKAHQIVINDLKSTLENMKIDKEKMITQMNFNIIDLQKEIYKLEIAGKNEIYKIEKKSEEELDEIRLAHEETKAMLTGQLNDLKVKYNELVERNRNNELEIRRRKWKLETETENWINKYDSEMAEYQTQFDKLQTDYDNEKKSLQELLKIFEPLEKEYLQVLEEQRIAKEKREAERAENEALVYWATVIQSFW
Sbjct:  239 DMANKLRGLLFQRLLTTPQERDEKARYLAAVCKKEKAHQIVINDLKSTLENMKIDKEKMITQMNFNIIDLQKEIYKLEIAGKNEIYKIEKKSEEELDEIRLAHEETKAMLTGQLNDLKVKYNELVERNRNNELEIRRRKWKLETETENWINKYDSEMAEYQTQFDKLQTDYDNEKKSLQELLKIFEPLEKEYLQVLEEQRIAKEKREAERAENEALVYWATVIQSFW 465

HSP 2 Score: 321.627 bits (823), Expect = 0.000e+0
Identity = 155/155 (100.00%), Postives = 155/155 (100.00%), Query Frame = 1 
Query:    1 VKFQEKFPNTSSKKKPRSIKPQENLILKPKSRHLETIESERILLILDDAIKNFNLIGSFESIMEDLEDYAFLLGKQLYRLFVNFKPFYMDYMKITIQILECKGQFQKSCLDVETENQKDVYNLPEDFWTIPINKLMKHELKQSAPSADDVQKVNV 465
            VKFQEKFPNTSSKKKPRSIKPQENLILKPKSRHLETIESERILLILDDAIKNFNLIGSFESIMEDLEDYAFLLGKQLYRLFVNFKPFYMDYMKITIQILECKGQFQKSCLDVETENQKDVYNLPEDFWTIPINKLMKHELKQSAPSADDVQKVNV
Sbjct:    3 VKFQEKFPNTSSKKKPRSIKPQENLILKPKSRHLETIESERILLILDDAIKNFNLIGSFESIMEDLEDYAFLLGKQLYRLFVNFKPFYMDYMKITIQILECKGQFQKSCLDVETENQKDVYNLPEDFWTIPINKLMKHELKQSAPSADDVQKVNV 157

HSP 3 Score: 150.214 bits (378), Expect = 0.000e+0
Identity = 68/69 (98.55%), Postives = 69/69 (100.00%), Query Frame = 2 
Query:  560 QKQLEKPNAENLCYTGNFSIYDCNGKFNLSVKDDPNNSILRSKYSYCIQKQSPCRKLCHETQRDMANKV 766
            QKQLEKPNAENLCYTGNFSIYDCNGKFNLSVKDDPNNSILRSKYSYCIQKQSPCRKLCHETQRDMANK+
Sbjct:  176 QKQLEKPNAENLCYTGNFSIYDCNGKFNLSVKDDPNNSILRSKYSYCIQKQSPCRKLCHETQRDMANKL 244
[Close]
BLAST of Dynein regulatory complex protein 10 vs. Planmine SMEST
Match: SMESG000036536.1 (SMESG000036536.1)

HSP 1 Score: 438.343 bits (1126), Expect = 6.556e-150
Identity = 273/273 (100.00%), Postives = 273/273 (100.00%), Query Frame = 3 
Query:  654 KMTPIIQFYVRSIVIAFRNNPHAVNCVMKHKEIWQIKYNVSLIRLIELMTQLRGLLFQRLLTTPQERDEKARYLAAVCKKEKAHQIVINDLKSTLENMKIDKEKMITQMNFNIIDLQKEIYKLEIAGXXXXXXXXXXXXXXLDEIRLAHEETKAMLTGQLNDLKVKYXXXXXXXXXXXXXXXXXKWKLETETENWINKYDSEMAEYQTQFDKLQTDYDNEKKSLQELLKIFEPLEKEYLQVLXXXXXXXXXXXXXXXXXXXLVYWATVIQSFW 1472
            KMTPIIQFYVRSIVIAFRNNPHAVNCVMKHKEIWQIKYNVSLIRLIELMTQLRGLLFQRLLTTPQERDEKARYLAAVCKKEKAHQIVINDLKSTLENMKIDKEKMITQMNFNIIDLQKEIYKLEIAGKNEIYKIEKKSEEELDEIRLAHEETKAMLTGQLNDLKVKYNELVERNRNNELEIRRRKWKLETETENWINKYDSEMAEYQTQFDKLQTDYDNEKKSLQELLKIFEPLEKEYLQVLEEQRIAKEKREAERAENEALVYWATVIQSFW
Sbjct:  173 KMTPIIQFYVRSIVIAFRNNPHAVNCVMKHKEIWQIKYNVSLIRLIELMTQLRGLLFQRLLTTPQERDEKARYLAAVCKKEKAHQIVINDLKSTLENMKIDKEKMITQMNFNIIDLQKEIYKLEIAGKNEIYKIEKKSEEELDEIRLAHEETKAMLTGQLNDLKVKYNELVERNRNNELEIRRRKWKLETETENWINKYDSEMAEYQTQFDKLQTDYDNEKKSLQELLKIFEPLEKEYLQVLEEQRIAKEKREAERAENEALVYWATVIQSFW 445

HSP 2 Score: 323.168 bits (827), Expect = 6.132e-105
Identity = 155/155 (100.00%), Postives = 155/155 (100.00%), Query Frame = 1 
Query:    1 VKFQEKFPNTSSKKKPRSIKPQENLILKPKSRHLETIESERILLILDDAIKNFNLIGSFESIMEDLEDYAFLLGKQLYRLFVNFKPFYMDYMKITIQILECKGQFQKSCLDVETENQKDVYNLPEDFWTIPINKLMKHELKQSAPSADDVQKVNV 465
            VKFQEKFPNTSSKKKPRSIKPQENLILKPKSRHLETIESERILLILDDAIKNFNLIGSFESIMEDLEDYAFLLGKQLYRLFVNFKPFYMDYMKITIQILECKGQFQKSCLDVETENQKDVYNLPEDFWTIPINKLMKHELKQSAPSADDVQKVNV
Sbjct:    3 VKFQEKFPNTSSKKKPRSIKPQENLILKPKSRHLETIESERILLILDDAIKNFNLIGSFESIMEDLEDYAFLLGKQLYRLFVNFKPFYMDYMKITIQILECKGQFQKSCLDVETENQKDVYNLPEDFWTIPINKLMKHELKQSAPSADDVQKVNV 157
[Close]
BLAST of Dynein regulatory complex protein 10 vs. Planmine SMEST
Match: SMESG000017912.1 (SMESG000017912.1)

HSP 1 Score: 86.6557 bits (213), Expect = 9.227e-18
Identity = 87/268 (32.46%), Postives = 148/268 (55.22%), Query Frame = 3 
Query:  669 IQFYVRSIVIAFRNNPHAVNCVMKHKEIWQIKYNVSLIRLIELMTQLRGLLFQRLLTTPQERDEKARYLAAVCKKEKAHQIVINDLKSTLENMKIDKEKMITQMNFNIIDLQKEIYKLEIAGXXXXXXXXXXXXXXLDEIRLAHEETKAMLTGQLNDLKVKYXXXXXXXXXXXXXXXXXKWKLETETENWINKYDSEMAEYQTQFDKLQTDYDNEKKSLQELLKIFEPLEKEYLQVLXXXXXXXXXXXXXXXXXXXLVYWATVIQSFW 1472
            ++F  R + I F+ NP A+  +   ++ W+IK +      I  + QL+ +L  RL+TTP E++E   YL  + +K KA+Q++INDL+  L+  +  K++ I++ N  I   Q EI+++E      I K + + E + +      E     L  ++   K +YN ++   R+ E E+R  K K E+  E  +  YD+ M + QT+++ +   Y  EK  L E+ + F+ +E+EYL+++EE+RIA+EKR A   E E L      IQ+FW
Sbjct:  196 LKFATRCLFIGFKANPAALTALTTGEKDWKIKRSPGDSMFISKLLQLKDILTLRLMTTPTEQNENHSYLRQMNEKFKANQMIINDLEIELKAAQEHKKEQISEKNDTIKKFQAEIHQVEKLSDENIKKTKLEMERQKEIDEKNSESVCQKLQQEIFQKKTEYNNILSEGRSGEKEMRANKIKKESALETNLQNYDTLMRQIQTEYEMVDEQYTEEKTQLYEMEERFKTIEEEYLKIMEEKRIAEEKRAAAAREEEILTKAVITIQAFW 463

HSP 2 Score: 53.9138 bits (128), Expect = 2.084e-7
Identity = 35/118 (29.66%), Postives = 63/118 (53.39%), Query Frame = 1 
Query:   34 SKKKPRSIKPQENLILKPKSRHLETIESERILLILDDAIKNFNLIGSFESIMEDLEDYAFLLGKQLYRLFVNFKPFYMDYMKITIQILECKGQFQKSCLDVETENQKDVYNLPEDFWT 387
            S K   +IK      L+P  + L T+E++RI+ +LD+ IK   +I +  S++ ++ED + +L +QL  L  N+K   +    +  ++   +G  Q    ++E E Q++     EDFWT
Sbjct:   31 SYKNASNIKIDCTKALEPTRKKLTTLETQRIMGVLDNCIKQSEIITAIPSVLNNIEDMSIVLTRQLIFLLDNYKMIKLKLDVVISKLDAIRGIRQNRKQEIE-EYQREQSLASEDFWT 147
The following BLAST results are available for this feature:
BLAST of Dynein regulatory complex protein 10 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 1
Match NameE-valueIdentityDescription
IQCD2.939e-1528.26IQ motif containing D [Source:HGNC Symbol;Acc:HGNC... [more]
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BLAST of Dynein regulatory complex protein 10 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Dynein regulatory complex protein 10 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Dynein regulatory complex protein 10 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 1
Match NameE-valueIdentityDescription
iqcd3.206e-1427.11IQ motif containing D [Source:ZFIN;Acc:ZDB-GENE-06... [more]
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BLAST of Dynein regulatory complex protein 10 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 1
Match NameE-valueIdentityDescription
iqcd1.393e-1730.86IQ motif containing D [Source:NCBI gene;Acc:100216... [more]
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BLAST of Dynein regulatory complex protein 10 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 2
Match NameE-valueIdentityDescription
Iqcd3.724e-1831.49IQ motif containing D [Source:MGI Symbol;Acc:MGI:1... [more]
Iqcd5.618e-1628.82IQ motif containing D [Source:MGI Symbol;Acc:MGI:1... [more]
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BLAST of Dynein regulatory complex protein 10 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q9D3V1|DRC10_MOUSE2.605e-1731.49Dynein regulatory complex protein 10 OS=Mus muscul... [more]
sp|Q5XIR6|DRC10_RAT9.613e-1531.88Dynein regulatory complex protein 10 OS=Rattus nor... [more]
sp|Q96DY2|DRC10_HUMAN1.411e-1428.26Dynein regulatory complex protein 10 OS=Homo sapie... [more]
sp|Q4R8Y5|DRC10_MACFA2.675e-1430.13Dynein regulatory complex protein 10 OS=Macaca fas... [more]
sp|Q17QH9|DRC10_BOVIN3.685e-1430.00Dynein regulatory complex protein 10 OS=Bos taurus... [more]
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BLAST of Dynein regulatory complex protein 10 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A1I8HTE44.984e-2435.19Uncharacterized protein OS=Macrostomum lignano OX=... [more]
A0A267EP975.269e-2435.19Uncharacterized protein (Fragment) OS=Macrostomum ... [more]
A0A1I8IRL05.698e-2435.19Uncharacterized protein OS=Macrostomum lignano OX=... [more]
A0A2B4SS111.699e-2336.06IQ domain-containing protein D OS=Stylophora pisti... [more]
A0A3M6V0122.730e-2336.43Uncharacterized protein OS=Pocillopora damicornis ... [more]
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BLAST of Dynein regulatory complex protein 10 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 2
Match NameE-valueIdentityDescription
iqcd2.306e-830.77IQ motif containing D [Source:NCBI gene;Acc:103032... [more]
iqcd2.306e-830.77IQ motif containing D [Source:NCBI gene;Acc:103032... [more]
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BLAST of Dynein regulatory complex protein 10 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Dynein regulatory complex protein 10 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Dynein regulatory complex protein 10 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 2
Match NameE-valueIdentityDescription
EDO449294.106e-2533.70Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO491213.710e-1027.41Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Dynein regulatory complex protein 10 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Dynein regulatory complex protein 10 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 3
Match NameE-valueIdentityDescription
SMESG000036536.10.000e+097.80SMESG000036536.1[more]
SMESG000036536.16.556e-150100.00SMESG000036536.1[more]
SMESG000017912.19.227e-1832.46SMESG000017912.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30008677 ID=SMED30008677|Name=Dynein regulatory complex protein 10|organism=Schmidtea mediterranea sexual|type=transcript|length=1621bp
GTAAAATTTCAAGAAAAATTTCCTAACACTTCGAGCAAAAAGAAACCCCG
ATCTATTAAGCCTCAAGAAAATCTGATTCTGAAACCAAAAAGTCGACATC
TCGAAACTATCGAATCTGAAAGGATCTTATTAATACTTGATGACGCCATT
AAAAATTTTAATTTGATTGGCTCTTTTGAAAGCATAATGGAAGATTTGGA
AGATTATGCTTTTCTGCTTGGGAAACAACTGTACCGATTGTTTGTCAATT
TCAAGCCGTTTTACATGGACTATATGAAAATTACAATTCAAATTTTGGAA
TGTAAAGGTCAGTTTCAGAAGAGCTGTCTAGATGTTGAAACAGAGAATCA
AAAGGATGTTTACAATTTGCCGGAGGATTTTTGGACGATACCAATAAACA
AATTAATGAAACATGAATTAAAACAATCAGCTCCATCCGCAGATGACGTT
CAAAAAGTAAATGTTGAGGAAATAAGAGAAAAACTTCCGGAATTGGAAGA
GAAGAAAAAAAAAGTTAAGTTTAAATTCCATGCATTTAAAATATTACAAC
ATTTACAGTCAAAAGCAATTGGAAAAACCAAATGCAGAAAATTTGTGTTA
CACGGGGAATTTTTCGATCTATGATTGTAATGGAAAATTTAACCTGAGTG
TAAAAGATGACCCCAATAATTCAATTTTACGTTCGAAGTATAGTTATTGC
ATTCAGAAACAATCCCCATGCCGTAAATTGTGTCATGAAACACAAAGAGA
TATGGCAAATAAAGTATAATGTGTCTTTGATCCGGTTGATCGAACTAATG
ACTCAGTTACGGGGATTATTGTTTCAACGGCTTTTGACAACTCCGCAAGA
AAGAGACGAAAAGGCTCGATATCTGGCAGCAGTGTGCAAAAAAGAAAAGG
CGCACCAAATCGTGATAAATGATTTGAAATCCACACTAGAAAATATGAAA
ATAGATAAAGAAAAAATGATTACTCAAATGAATTTTAATATAATTGATTT
ACAAAAAGAAATTTATAAATTGGAAATTGCTGGAAAAAATGAAATCTATA
AAATAGAAAAAAAATCTGAAGAAGAATTGGATGAAATTAGATTAGCACAT
GAAGAAACCAAGGCAATGTTAACGGGTCAATTGAATGATCTCAAGGTTAA
ATATAATGAACTTGTTGAAAGAAATAGAAACAATGAATTGGAAATCAGGC
GTCGAAAATGGAAATTAGAAACGGAAACTGAAAATTGGATTAATAAATAT
GACAGTGAAATGGCAGAATATCAAACGCAATTTGACAAACTCCAAACGGA
TTATGATAATGAGAAAAAATCACTTCAAGAATTGCTGAAAATATTCGAAC
CGTTAGAAAAGGAATATTTACAAGTATTAGAAGAACAGAGAATAGCGAAA
GAAAAACGTGAAGCTGAGCGTGCGGAAAATGAGGCGTTAGTGTATTGGGC
CACTGTTATCCAATCATTTTGGAGGGCCTGGAAAGCTAGAAAAGCAATGC
GGAAAAATCGTCGTCGTTAAATTATATATTACTGATATGAAAATGTTAAT
AAATGGACTTTGATTTGTCAGGAATTAAGGAAATTATGTGATTTTTATTG
TTGTACTTACTTTGCAACGCT
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protein sequence of SMED30008677-orf-1

>SMED30008677-orf-1 ID=SMED30008677-orf-1|Name=SMED30008677-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=208bp
VKFQEKFPNTSSKKKPRSIKPQENLILKPKSRHLETIESERILLILDDAI
KNFNLIGSFESIMEDLEDYAFLLGKQLYRLFVNFKPFYMDYMKITIQILE
CKGQFQKSCLDVETENQKDVYNLPEDFWTIPINKLMKHELKQSAPSADDV
QKVNVEEIREKLPELEEKKKKVKFKFHAFKILQHLQSKAIGKTKCRKFVL
HGEFFDL*
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protein sequence of SMED30008677-orf-2

>SMED30008677-orf-2 ID=SMED30008677-orf-2|Name=SMED30008677-orf-2|organism=Schmidtea mediterranea sexual|type=polypeptide|length=288bp
MTPIIQFYVRSIVIAFRNNPHAVNCVMKHKEIWQIKYNVSLIRLIELMTQ
LRGLLFQRLLTTPQERDEKARYLAAVCKKEKAHQIVINDLKSTLENMKID
KEKMITQMNFNIIDLQKEIYKLEIAGKNEIYKIEKKSEEELDEIRLAHEE
TKAMLTGQLNDLKVKYNELVERNRNNELEIRRRKWKLETETENWINKYDS
EMAEYQTQFDKLQTDYDNEKKSLQELLKIFEPLEKEYLQVLEEQRIAKEK
REAERAENEALVYWATVIQSFWRAWKARKAMRKNRRR*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: cellular component
TermDefinition
GO:0005737cytoplasm
GO:0005856cytoskeleton
GO:0005929cilium
GO:0031514motile cilium
GO:0042995cell projection
GO:0005575cellular_component
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0002089reproductive organ
Vocabulary: INTERPRO
TermDefinition
IPR042815DRC10
IPR000048IQ_motif_EF-hand-BS
Vocabulary: molecular function
TermDefinition
GO:0005515protein binding
GO:0003674molecular_function
Vocabulary: biological process
TermDefinition
GO:0008150biological_process
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableCOILSCoilCoilcoord: 195..229
NoneNo IPR availableCOILSCoilCoilcoord: 152..179
NoneNo IPR availableCOILSCoilCoilcoord: 239..259
NoneNo IPR availableCOILSCoilCoilcoord: 87..107
IPR000048IQ motif, EF-hand binding sitePFAMPF00612IQcoord: 265..282
e-value: 1.3E-4
score: 21.4
IPR000048IQ motif, EF-hand binding sitePROSITEPS50096IQcoord: 265..287
score: 7.876
IPR042815Dynein regulatory complex protein 10PANTHERPTHR31598FAMILY NOT NAMEDcoord: 9..287