Transmembrane emp24 domain-containing protein

Overview
NameTransmembrane emp24 domain-containing protein
Smed IDSMED30008676
Length (bp)927
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Transmembrane emp24 domain-containing protein (SMED30008676) t-SNE clustered cells

Violin plots show distribution of expression levels for Transmembrane emp24 domain-containing protein (SMED30008676) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Transmembrane emp24 domain-containing protein (SMED30008676) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Transmembrane emp24 domain-containing protein (SMED30008676) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30008676

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 4

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
nervous systemSMED30008676h1SMcG0018648 dd_Smed_v4_2833_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30008676h1SMcG0018648 dd_Smed_v4_2833_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
muscle cellSMED30008676h1SMcG0018648 dd_Smed_v4_2833_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30008676h1SMcG0018648 dd_Smed_v4_2833_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Transmembrane emp24 domain-containing protein vs. Ensembl Human
Match: TMED2 (transmembrane p24 trafficking protein 2 [Source:HGNC Symbol;Acc:HGNC:16996])

HSP 1 Score: 215.698 bits (548), Expect = 2.018e-69
Identity = 100/182 (54.95%), Postives = 136/182 (74.73%), Query Frame = 3 
Query:   93 SFFISVSPNVEECFFDRIKPDTDMLLLYEVAEGGSLDIDAKVLDPSGSILYSAVKKSDDKFTFRTKVDGIYKYCFSNTMSSVTNKILMFSLDTI-SPAKKD-SPDSH-SKLEEMVSELDKALTTVKHEQEYMETREKIHRKINENTNSRVLLWAIFEACVLIIMSAGQVYYLKRFFEVRRVV 629
             +F+S+  + EECFF+R+   T M L++EVAEGG LDID ++  P    +Y   ++S  K+TF   +DG YK+CFSN MS++T KI+MF++D   +P  +D   ++H +KLEEM++EL  A+T VKHEQEYME RE+IHR IN+NTNSRV+LW+ FEA VL+ M+ GQ+YYLKRFFEVRRVV
Sbjct:   20 GYFVSIDAHAEECFFERVTSGTKMGLIFEVAEGGFLDIDVEITGPDNKGIYKGDRESSGKYTFAAHMDGTYKFCFSNRMSTMTPKIVMFTIDIGEAPKGQDMETEAHQNKLEEMINELAVAMTAVKHEQEYMEVRERIHRAINDNTNSRVVLWSFFEALVLVAMTLGQIYYLKRFFEVRRVV 201
[Close]
BLAST of Transmembrane emp24 domain-containing protein vs. Ensembl Human
Match: TMED2 (transmembrane p24 trafficking protein 2 [Source:HGNC Symbol;Acc:HGNC:16996])

HSP 1 Score: 153.68 bits (387), Expect = 2.526e-46
Identity = 73/116 (62.93%), Postives = 95/116 (81.90%), Query Frame = 3 
Query:  291 VDGIYKYCFSNTMSSVTNKILMFSLDTI-SPAKKD-SPDSH-SKLEEMVSELDKALTTVKHEQEYMETREKIHRKINENTNSRVLLWAIFEACVLIIMSAGQVYYLKRFFEVRRVV 629
            +DG YK+CFSN MS++T KI+MF++D   +P  +D   ++H +KLEEM++EL  A+T VKHEQEYME RE+IHR IN+NTNSRV+LW+ FEA VL+ M+ GQ+YYLKRFFEVRRVV
Sbjct:    1 MDGTYKFCFSNRMSTMTPKIVMFTIDIGEAPKGQDMETEAHQNKLEEMINELAVAMTAVKHEQEYMEVRERIHRAINDNTNSRVVLWSFFEALVLVAMTLGQIYYLKRFFEVRRVV 116
[Close]
BLAST of Transmembrane emp24 domain-containing protein vs. Ensembl Human
Match: TMED2 (transmembrane p24 trafficking protein 2 [Source:HGNC Symbol;Acc:HGNC:16996])

HSP 1 Score: 147.132 bits (370), Expect = 4.082e-43
Identity = 72/148 (48.65%), Postives = 100/148 (67.57%), Query Frame = 3 
Query:   93 SFFISVSPNVEECFFDRIKPDTDMLLLYEVAEGGSLDIDAKVLDPSGSILYSAVKKSDDKFTFRTKVDGIYKYCFSNTMSSVTNKILMFSLDTISPAKK----------DSPDSH-SKLEEMVSELDKALTTVKHEQEYMETREKIHR 503
             +F+S+  + EECFF+R+   T M L++EVAEGG LDID ++  P    +Y   ++S  K+TF   +DG YK+CFSN MS++T KI+MF++D I  A K          D+ D+H +KLEEM++EL  A+T VKHEQEYME RE+IHR
Sbjct:   20 GYFVSIDAHAEECFFERVTSGTKMGLIFEVAEGGFLDIDVEITGPDNKGIYKGDRESSGKYTFAAHMDGTYKFCFSNRMSTMTPKIVMFTID-IGEAPKGQDMETEGGGDTWDAHQNKLEEMINELAVAMTAVKHEQEYMEVRERIHR 166
[Close]
BLAST of Transmembrane emp24 domain-containing protein vs. Ensembl Human
Match: TMED7 (transmembrane p24 trafficking protein 7 [Source:HGNC Symbol;Acc:HGNC:24253])

HSP 1 Score: 115.161 bits (287), Expect = 3.422e-30
Identity = 63/175 (36.00%), Postives = 95/175 (54.29%), Query Frame = 3 
Query:  117 NVEECFFDRIKPDTDMLLLYEVAEGGSLDIDAKVLDPSGSILYSAVKKSDDKFTFRTKVDGIYKYCFSNTMSSVTNKILMFSLDTIS-PAKKDSPDSHSKLEEMVS---ELDKALTTVKHEQEYMETREKIHRKINENTNSRVLLWAIFEACVLIIMSAGQVYYLKRFFEVRRVV 629
            N ++CF++ I   T   L ++V  GG  D+D ++ DP G +LY  +KK  D FTF    +G YK+CFSN  S+ T+K + F       P    S +  S L +M S    + +AL +V   Q +   RE   R   E+ N+RV  W++ EA +L+++S GQV+ LK FF  +R  
Sbjct:   44 NAKQCFYEDIAQGTKCTLEFQVITGGHYDVDCRLEDPDGKVLYKEMKKQYDSFTFTASKNGTYKFCFSNEFSTFTHKTVYFDFQVGEDPPLFPSENRVSALTQMESACVSIHEALKSVIDYQTHFRLREAQGRSRAEDLNTRVAYWSVGEALILLVVSIGQVFLLKSFFSDKRTT 218
[Close]
BLAST of Transmembrane emp24 domain-containing protein vs. Ensembl Human
Match: TMED3 (transmembrane p24 trafficking protein 3 [Source:HGNC Symbol;Acc:HGNC:28889])

HSP 1 Score: 108.612 bits (270), Expect = 9.894e-28
Identity = 58/176 (32.95%), Postives = 91/176 (51.70%), Query Frame = 3 
Query:  117 NVEECFFDRIKPDTDMLLLYEVAEGGSLDIDAKVLDPSGSILYSAVKKSDDKFTFRTKVDGIYKYCFSNTMSSVTNKILMFSLDT-----ISPAKKDSPDSHSKLEEMVSELDKALTTVKHEQEYMETREKIHRKINENTNSRVLLWAIFEACVLIIMSAGQVYYLKRFFEVRRVV 629
            N ++CF + ++      L Y+V  GG  D+D  V DP G+ +Y   KK  D FT+R +V G+Y++CFSN  S+ ++K + F         I P   +   + +++E     + +AL TV   Q +   RE   R   E+ NSRV  W++ E   L ++S  QV  LK FF  +R +
Sbjct:   36 NAKQCFHEEVEQGVKFSLDYQVITGGHYDVDCYVEDPQGNTIYRETKKQYDSFTYRAEVKGVYQFCFSNEFSTFSHKTVYFDFQVGDEPPILPDMGNRVTALTQMESACVTIHEALKTVIDSQTHYRLREAQDRARAEDLNSRVSYWSVGETIALFVVSFSQVLLLKSFFTEKRPI 211
[Close]
BLAST of Transmembrane emp24 domain-containing protein vs. Ensembl Celegans
Match: sel-9 (Suppressor/enhancer of lin-12 protein 9 [Source:UniProtKB/Swiss-Prot;Acc:O17528])

HSP 1 Score: 213.772 bits (543), Expect = 4.573e-69
Identity = 104/200 (52.00%), Postives = 137/200 (68.50%), Query Frame = 3 
Query:   54 IFCVLFILLHSAFSFFISVSPNVEECFFDRIKPDTDMLLLYEVAEGGSLDIDAKVLDPSGSILYSAVKKSDDKFTFRTKVDGIYKYCFSNTMSSVTNKILMFSLDTISPAKKDSPDSHS--------KLEEMVSELDKALTTVKHEQEYMETREKIHRKINENTNSRVLLWAIFEACVLIIMSAGQVYYLKRFFEVRRVV 629
            I  VLF+    A S+FI V  N E+CFFDR+   T M L++EVAEGG LDID K+  P    +Y   ++S  KFTF   +DG+Y YCF N MS++T K +MF+++   P ++ +P + +        KLEEMV EL  AL +VKHEQEYME RE++HR INENTNSRV++WA FEA VL+ M+ GQ++YLKRFFEVR +V
Sbjct:    7 ILAVLFVT--PAASYFIHVDANEEQCFFDRLTSGTKMGLMFEVAEGGFLDIDVKITGPDNKEIYKGERESSGKFTFAAHMDGVYTYCFGNKMSTMTPKAVMFTVEITEPHQQ-APGAAANQDAADNAKLEEMVRELSSALMSVKHEQEYMEVRERVHRNINENTNSRVVMWAAFEAFVLVGMTVGQIFYLKRFFEVRTMV 203
[Close]
BLAST of Transmembrane emp24 domain-containing protein vs. Ensembl Celegans
Match: F57B10.5 (pep chromosome:WBcel235:I:6562699:6563660:1 gene:WBGene00019003.1 transcript:F57B10.5.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:F57B10.5)

HSP 1 Score: 114.775 bits (286), Expect = 1.430e-30
Identity = 55/174 (31.61%), Postives = 92/174 (52.87%), Query Frame = 3 
Query:  117 NVEECFFDRIKPDTDMLLLYEVAEGGSLDIDAKVLDPSGSILYSAVKKSDDKFTFRTKVDGIYKYCFSNTMSSVTNKILMFSL-----DTISPAKKDSPDSHSKLEEMVSELDKALTTVKHEQEYMETREKIHRKINENTNSRVLLWAIFEACVLIIMSAGQVYYLKRFFEVRR 623
            N  +CF++ +K D D +  ++V  GG  D+D  + DP+G +LY   KK  D   F+ +V+G YK CFSN  S+ ++KI+         + +  A      + ++LE     +   L T+   Q +   RE   RK  E  N RV++W++ ++ V++ +  GQV+ LK FF  +R
Sbjct:   27 NANQCFYEDLKKDVDTVFEFQVVTGGHYDVDLIIEDPNGKVLYKDTKKQYDSINFKAEVEGTYKACFSNEFSTFSHKIVYMDWQFGDQNALHAAVTQGAHAMTQLENYAVAIGDKLRTIDDYQTHHRLREATGRKRAEELNERVMIWSLGQSAVVVFIGIGQVFLLKSFFNDKR 200
[Close]
BLAST of Transmembrane emp24 domain-containing protein vs. Ensembl Celegans
Match: Y60A3A.9 (pep chromosome:WBcel235:V:19946691:19949093:-1 gene:WBGene00013360.1 transcript:Y60A3A.9.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:Y60A3A.9)

HSP 1 Score: 77.7962 bits (190), Expect = 9.307e-17
Identity = 55/211 (26.07%), Postives = 101/211 (47.87%), Query Frame = 3 
Query:   51 KIFCVLFILLHSAFSFFISVSPNVEECFFDRIKPDTDMLL------LYEVAEGG-----SLDIDAKVLDPSGSILYSAVKKSDDKFTFRTKVDGIYKYC-FSNTMSSVTNKILMFSLDTISP------AKKDSPDSHSKLEEMVSELDKALTTVKHEQEYMETREKIHRKINENTNSRVLLWAIFEACVLIIMSAGQVYYLKRFFEVRRVV 629
            ++   L  L   A S +  ++   ++CF + I PD  M+       LY+    G     ++ +  +V DP   ++ S +  ++ +FTF +   G +  C +SN+ +      L   LD  +       A+    D  ++L+  + +L   +  +  EQ Y   RE+  R+ +E+TNSRV  W+I +  VL I  A Q+ +L+ FFE +++V
Sbjct:    2 RLLIALLSLATYADSLYFHIAETEKKCFIEEI-PDETMVTGNYKVQLYDPNTKGYGDYPNIGMHVEVKDPEDKVILSKLYTAEGRFTFTSNTPGEHVICIYSNSTAWFNGAQLRVHLDIQAGDHAQDYAQIAQKDKLNELQLRIRQLLDQVDQITKEQNYQRYREERFRQTSESTNSRVFYWSIAQVVVLAITGAWQMRHLRGFFEAKKLV 211
[Close]
BLAST of Transmembrane emp24 domain-containing protein vs. Ensembl Celegans
Match: F47G9.1 (pep chromosome:WBcel235:V:11323965:11326964:-1 gene:WBGene00009829.1 transcript:F47G9.1.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:F47G9.1)

HSP 1 Score: 58.9214 bits (141), Expect = 4.214e-10
Identity = 52/206 (25.24%), Postives = 91/206 (44.17%), Query Frame = 3 
Query:   54 IFCVLFILLHSAFSFFISVSPNVEECFFDRIKPDTDMLLLYEVAEGGSLDIDAKVLDPSGSILYSAVKKSD--DKFTFRTKVDGIYKYCFSNTMSS------------VTNKILMFSLDTISPAKKDSPDSHSKLEEMVSELDKALTTVKHEQEYMETREKIHRKINENTNSRVLLWAIFEACVLIIMSAGQVYYLKRFFEVRRVV 629
            IF    +L HS   F+  V P  ++C  + I  +  +   YE ++G        V D  G  LY     +D   KF F      I++ C  N   +            + + +   + D I+ A+K  P     LE  +  L+    ++  +  +M  RE+  R  NE+TNSRVL  +IF    L+ ++  QV +L+ +F+ ++++
Sbjct:    6 IFLSAIVLAHS-LRFY--VPPKEKKCLKEEIHKNVVVTGEYEFSQGIQYTGSIHVTDTRGHTLYKRENFADLKGKFAFTADEYDIFEICIENHPPAGHPGEKREVSLILKHGVEAKNYDDIAKAEKLKP-----LEVELRRLEDMADSITKDFAFMRQREEEMRNTNESTNSRVLYLSIFSMLCLLGLAIWQVLFLRNYFKSKKLI 203
[Close]
BLAST of Transmembrane emp24 domain-containing protein vs. Ensembl Celegans
Match: K08E4.6 (pep chromosome:WBcel235:IV:12077107:12078162:-1 gene:WBGene00010670.1 transcript:K08E4.6.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:K08E4.6)

HSP 1 Score: 55.8398 bits (133), Expect = 5.715e-9
Identity = 49/205 (23.90%), Postives = 88/205 (42.93%), Query Frame = 3 
Query:   75 LLHSAFSFFISVSPNVEECFF---DRIKPDTDMLLLYEVAEGGSLDIDAKVLDPSGSILYSAVKKSDDKFTFRTKVDGIYKYCFSNTMSSVTNKILMFSL------------DTISPAKKDSPDSHSKLEEMVSELDK----------ALTTVKHEQEYMETREKIHRKINENTNSRVLLWAIFEACVLIIMSAGQVYYLKRFFE 614
            +L   + F + V     +CFF   D  K  T + + Y+V +GG L+I+  +L  + +IL     K D          G Y+ CF N+ S  + K++ F +            D  + A+ DS D  +K+ E+   +D+           L  V++ Q  +   E   R +      RV  W++    V++ ++  QV+ ++  FE
Sbjct:   18 ILCGEYDFTVEVPAGKFQCFFQPVDLAKHKT-LEVDYQVIDGGDLNINFMILHGA-NILKQDQLKVDGSHRIELNQPGDYQVCFDNSFSYQSRKVVFFEIFLFDAHGNLDEADLSAMARTDS-DLSAKMNELGVTIDEFHRRANGIKNNLNKVEYHQALLRAHEARDRAVMSANFDRVTFWSVVHTLVMVGVAGVQVFMIRSLFE 219
[Close]
BLAST of Transmembrane emp24 domain-containing protein vs. Ensembl Fly
Match: CHOp24 (gene:FBgn0029709 transcript:FBtr0343566)

HSP 1 Score: 195.282 bits (495), Expect = 1.150e-61
Identity = 91/189 (48.15%), Postives = 131/189 (69.31%), Query Frame = 3 
Query:   84 SAFSFFISVSPNVEECFFDRIKPDTDMLLLYEVAEGGSLDIDAKVLDPSGSILYSAVKKSDDKFTFRTKVDGIYKYCFSNTMSSVTNKILMFSLDTISPAKKDSPDS-------HSKLEEMVSELDKALTTVKHEQEYMETREKIHRKINENTNSRVLLWAIFEACVLIIMSAGQVYYLKRFFEVRRVV 629
            ++ +F +SV  + EECFF+ ++  T   + +EV +GG LD+D K+  P   +++ + K+S  K+TF     G Y  CF+N  SS+T K++MFS+D +  A + +P +       H+KLE+M+ EL   LT+VKHEQEYM  R+KIHR +NENTNSRV+LW+ FEA VL++M+ GQVYYLKRFFEV+RVV
Sbjct:   21 TSHAFIVSVDAHNEECFFENVEGGTKFGVTFEVIDGGFLDVDIKISGPDNHVMHESEKESSGKYTFVAPAKGTYTVCFNNERSSMTPKLVMFSID-VGDAPQRAPGAPGEEEVGHTKLEDMIRELSGTLTSVKHEQEYMHVRDKIHRSVNENTNSRVVLWSTFEALVLVLMTVGQVYYLKRFFEVKRVV 208
[Close]
BLAST of Transmembrane emp24 domain-containing protein vs. Ensembl Fly
Match: CHOp24 (gene:FBgn0029709 transcript:FBtr0070675)

HSP 1 Score: 195.282 bits (495), Expect = 1.150e-61
Identity = 91/189 (48.15%), Postives = 131/189 (69.31%), Query Frame = 3 
Query:   84 SAFSFFISVSPNVEECFFDRIKPDTDMLLLYEVAEGGSLDIDAKVLDPSGSILYSAVKKSDDKFTFRTKVDGIYKYCFSNTMSSVTNKILMFSLDTISPAKKDSPDS-------HSKLEEMVSELDKALTTVKHEQEYMETREKIHRKINENTNSRVLLWAIFEACVLIIMSAGQVYYLKRFFEVRRVV 629
            ++ +F +SV  + EECFF+ ++  T   + +EV +GG LD+D K+  P   +++ + K+S  K+TF     G Y  CF+N  SS+T K++MFS+D +  A + +P +       H+KLE+M+ EL   LT+VKHEQEYM  R+KIHR +NENTNSRV+LW+ FEA VL++M+ GQVYYLKRFFEV+RVV
Sbjct:   21 TSHAFIVSVDAHNEECFFENVEGGTKFGVTFEVIDGGFLDVDIKISGPDNHVMHESEKESSGKYTFVAPAKGTYTVCFNNERSSMTPKLVMFSID-VGDAPQRAPGAPGEEEVGHTKLEDMIRELSGTLTSVKHEQEYMHVRDKIHRSVNENTNSRVVLWSTFEALVLVLMTVGQVYYLKRFFEVKRVV 208
[Close]
BLAST of Transmembrane emp24 domain-containing protein vs. Ensembl Fly
Match: CG9308 (gene:FBgn0034681 transcript:FBtr0071749)

HSP 1 Score: 122.094 bits (305), Expect = 2.268e-33
Identity = 66/203 (32.51%), Postives = 106/203 (52.22%), Query Frame = 3 
Query:   45 MYKIFCVLFILLHSAFSFFISVSPNVEECFFDRIKPDTDMLLLYEVAEGGSLDIDAKVLDPSGSILYSAVKKSDDKFTFRTKVDGIYKYCFSNTMSSVTNKILMFSLDTI--------SPAKKDSPDSHSKLEEMVSELDKALTTVKHEQEYMETREKIHRKINENTNSRVLLWAIFEACVLIIMSAGQVYYLKRFFEVRRVV 629
            M     ++ +L  +A  F +++  +   CF+D       + + +EV EGG  D+  ++  P    L+ + + +   FTF    +G Y+ CF N MS++T KILMF             S  + D     + ++ M+++L   L  VK EQEYM  R + H ++++    RVL W+IF   +LII +  +VYYLK FFEV+RVV
Sbjct:    1 MLSAIVLVLVLFQAACGFIVTLDAHETMCFYDHANVSDKVTVSFEVMEGGFKDVGVEIAGPDDDRLHHSKQDTMGSFTFTAMKEGRYQLCFDNKMSTMTPKILMFQFHVARAIEFYMDSSKRVDDVIEQATVQSMINQLSAKLGAVKMEQEYMHFRYRGHLEVSDMVELRVLAWSIFGPMMLIITAVLEVYYLKHFFEVKRVV 203
[Close]
BLAST of Transmembrane emp24 domain-containing protein vs. Ensembl Fly
Match: p24-1 (gene:FBgn0030341 transcript:FBtr0073604)

HSP 1 Score: 102.449 bits (254), Expect = 8.721e-26
Identity = 55/196 (28.06%), Postives = 96/196 (48.98%), Query Frame = 3 
Query:   54 IFCVLFILLH--SAFSFFISVSPNVEECFFDRIKPDTDMLLLYEVAEGGSLDIDAKVLDPSGSILYSAVKKSDDKFTFRTKVDGIYKYCFSNTMSSVTNKILMFSLDTISPAKKDSPDSHS----KLEEMVSELDKALTTVKHEQEYMETREKIHRKINENTNSRVLLWAIFEACVLIIMSAGQVYYLKRFFEVRR 623
            +F V  +++H  SA  F   ++ N  +CF++ IK ++     ++V+ GG LD+D  + DP G ++YS  K + D   F  +  G+Y  CF N  S+ ++KI+               D H+    ++E     + K L  +   Q +   RE   RK  E+ N RV++W+  E   +I++   Q+  L+ FF  R+
Sbjct:    7 VFAVA-LMMHCISAVEFTFDLADNAVDCFYEEIKKNSSAYFEFQVSAGGQLDVDVTLKDPQGKVIYSLEKATFDSHQFVAETTGVYTACFGNQFSAFSHKIVYVDFQVGEEPALPGVDEHATVLTQMETSSQAIHKGLNDILDAQTHHRLREAQGRKRAEDLNQRVMVWSSLETAAVIVIGLVQIMVLRNFFTDRK 201
[Close]
BLAST of Transmembrane emp24 domain-containing protein vs. Ensembl Fly
Match: p24-1 (gene:FBgn0030341 transcript:FBtr0334455)

HSP 1 Score: 102.449 bits (254), Expect = 8.721e-26
Identity = 55/196 (28.06%), Postives = 96/196 (48.98%), Query Frame = 3 
Query:   54 IFCVLFILLH--SAFSFFISVSPNVEECFFDRIKPDTDMLLLYEVAEGGSLDIDAKVLDPSGSILYSAVKKSDDKFTFRTKVDGIYKYCFSNTMSSVTNKILMFSLDTISPAKKDSPDSHS----KLEEMVSELDKALTTVKHEQEYMETREKIHRKINENTNSRVLLWAIFEACVLIIMSAGQVYYLKRFFEVRR 623
            +F V  +++H  SA  F   ++ N  +CF++ IK ++     ++V+ GG LD+D  + DP G ++YS  K + D   F  +  G+Y  CF N  S+ ++KI+               D H+    ++E     + K L  +   Q +   RE   RK  E+ N RV++W+  E   +I++   Q+  L+ FF  R+
Sbjct:    7 VFAVA-LMMHCISAVEFTFDLADNAVDCFYEEIKKNSSAYFEFQVSAGGQLDVDVTLKDPQGKVIYSLEKATFDSHQFVAETTGVYTACFGNQFSAFSHKIVYVDFQVGEEPALPGVDEHATVLTQMETSSQAIHKGLNDILDAQTHHRLREAQGRKRAEDLNQRVMVWSSLETAAVIVIGLVQIMVLRNFFTDRK 201
[Close]
BLAST of Transmembrane emp24 domain-containing protein vs. Ensembl Zebrafish
Match: tmed2 (transmembrane p24 trafficking protein 2 [Source:ZFIN;Acc:ZDB-GENE-030131-269])

HSP 1 Score: 220.32 bits (560), Expect = 2.650e-71
Identity = 106/204 (51.96%), Postives = 145/204 (71.08%), Query Frame = 3 
Query:   51 KIFCVLFILLHSAFSFFISVSPNVEECFFDRIKPDTDMLLLYEVAEGGSLDIDAKVLDPSGSILYSAVKKSDDKFTFRTKVDGIYKYCFSNTMSSVTNKILMFSLDTISPAKK----------DSPDSH-SKLEEMVSELDKALTTVKHEQEYMETREKIHRKINENTNSRVLLWAIFEACVLIIMSAGQVYYLKRFFEVRRVV 629
            ++  +L  L ++A  +F+S+  + EECF++R+   T M L++EVAEGG LDID K+  P G  +Y   ++S  K++    +DG YK+CFSN MS++T KI+MF++D I  A K          DS D+H +KLEEM++EL  A+T VKHEQEYME RE+IHR IN+NTNSRV+LW+ FEA VL+ M+ GQ+YYLKRFFEVRRVV
Sbjct:    6 ELIVLLCALSYTASGYFVSIDAHAEECFYERVNSGTKMSLMFEVAEGGFLDIDVKITGPDGKQIYKGDRESSGKYSVAAHMDGTYKFCFSNEMSTMTPKIVMFTID-IGEAPKGQDMETEGGGDSWDAHQNKLEEMINELAVAMTAVKHEQEYMEVRERIHRAINDNTNSRVVLWSFFEALVLVAMTLGQIYYLKRFFEVRRVV 208
[Close]
BLAST of Transmembrane emp24 domain-containing protein vs. Ensembl Zebrafish
Match: tmed2 (transmembrane p24 trafficking protein 2 [Source:ZFIN;Acc:ZDB-GENE-030131-269])

HSP 1 Score: 218.779 bits (556), Expect = 9.561e-71
Identity = 102/196 (52.04%), Postives = 144/196 (73.47%), Query Frame = 3 
Query:   51 KIFCVLFILLHSAFSFFISVSPNVEECFFDRIKPDTDMLLLYEVAEGGSLDIDAKVLDPSGSILYSAVKKSDDKFTFRTKVDGIYKYCFSNTMSSVTNKILMFSLDTI-SPAKKD-SPDSH-SKLEEMVSELDKALTTVKHEQEYMETREKIHRKINENTNSRVLLWAIFEACVLIIMSAGQVYYLKRFFEVRRVV 629
            ++  +L  L ++A  +F+S+  + EECF++R+   T M L++EVAEGG LDID K+  P G  +Y   ++S  K++    +DG YK+CFSN MS++T KI+MF++D   +P  +D   ++H +KLEEM++EL  A+T VKHEQEYME RE+IHR IN+NTNSRV+LW+ FEA VL+ M+ GQ+YYLKRFFEVRRVV
Sbjct:    6 ELIVLLCALSYTASGYFVSIDAHAEECFYERVNSGTKMSLMFEVAEGGFLDIDVKITGPDGKQIYKGDRESSGKYSVAAHMDGTYKFCFSNEMSTMTPKIVMFTIDIGEAPKGQDMETEAHQNKLEEMINELAVAMTAVKHEQEYMEVRERIHRAINDNTNSRVVLWSFFEALVLVAMTLGQIYYLKRFFEVRRVV 201
[Close]
BLAST of Transmembrane emp24 domain-containing protein vs. Ensembl Zebrafish
Match: tmed7 (transmembrane p24 trafficking protein 7 [Source:ZFIN;Acc:ZDB-GENE-040426-2570])

HSP 1 Score: 113.235 bits (282), Expect = 1.110e-29
Identity = 61/190 (32.11%), Postives = 99/190 (52.11%), Query Frame = 3 
Query:   72 ILLHSAFSFFISVSPNVEECFFDRIKPDTDMLLLYEVAEGGSLDIDAKVLDPSGSILYSAVKKSDDKFTFRTKVDGIYKYCFSNTMSSVTNKILMFSL----DTISPAKKDSPDSHSKLEEMVSELDKALTTVKHEQEYMETREKIHRKINENTNSRVLLWAIFEACVLIIMSAGQVYYLKRFFEVRRVV 629
            + L SA      +  N ++CF++ I   T   L ++V  GG  D+D ++ DP G++LY  +KK  D FTF    +G YK+CFSN  S+ T+K + F      D      ++   + +++E     + +AL +V   Q +   RE   R   E+ NSRV  W++ EA +L+++S  QV  L+ FF  R+  
Sbjct:   21 VGLSSASELTFELPDNAKQCFYEDITIGTKCTLEFQVVTGGHYDVDCRLEDPEGTVLYKEMKKQYDSFTFSAARNGTYKFCFSNEFSTFTHKTVYFDFQVGDDPPLFPNENRVTALTQMESACVSIHEALKSVMDYQTHFRLREAQGRSRAEDLNSRVAFWSVGEALILLVVSVSQVLLLRSFFSDRKTT 210
[Close]
BLAST of Transmembrane emp24 domain-containing protein vs. Ensembl Zebrafish
Match: tmed7 (transmembrane p24 trafficking protein 7 [Source:ZFIN;Acc:ZDB-GENE-040426-2570])

HSP 1 Score: 113.235 bits (282), Expect = 1.110e-29
Identity = 61/190 (32.11%), Postives = 99/190 (52.11%), Query Frame = 3 
Query:   72 ILLHSAFSFFISVSPNVEECFFDRIKPDTDMLLLYEVAEGGSLDIDAKVLDPSGSILYSAVKKSDDKFTFRTKVDGIYKYCFSNTMSSVTNKILMFSL----DTISPAKKDSPDSHSKLEEMVSELDKALTTVKHEQEYMETREKIHRKINENTNSRVLLWAIFEACVLIIMSAGQVYYLKRFFEVRRVV 629
            + L SA      +  N ++CF++ I   T   L ++V  GG  D+D ++ DP G++LY  +KK  D FTF    +G YK+CFSN  S+ T+K + F      D      ++   + +++E     + +AL +V   Q +   RE   R   E+ NSRV  W++ EA +L+++S  QV  L+ FF  R+  
Sbjct:   21 VGLSSASELTFELPDNAKQCFYEDITIGTKCTLEFQVVTGGHYDVDCRLEDPEGTVLYKEMKKQYDSFTFSAARNGTYKFCFSNEFSTFTHKTVYFDFQVGDDPPLFPNENRVTALTQMESACVSIHEALKSVMDYQTHFRLREAQGRSRAEDLNSRVAFWSVGEALILLVVSVSQVLLLRSFFSDRKTT 210
[Close]
BLAST of Transmembrane emp24 domain-containing protein vs. Ensembl Zebrafish
Match: tmed7 (transmembrane p24 trafficking protein 7 [Source:ZFIN;Acc:ZDB-GENE-040426-2570])

HSP 1 Score: 113.235 bits (282), Expect = 1.110e-29
Identity = 61/190 (32.11%), Postives = 99/190 (52.11%), Query Frame = 3 
Query:   72 ILLHSAFSFFISVSPNVEECFFDRIKPDTDMLLLYEVAEGGSLDIDAKVLDPSGSILYSAVKKSDDKFTFRTKVDGIYKYCFSNTMSSVTNKILMFSL----DTISPAKKDSPDSHSKLEEMVSELDKALTTVKHEQEYMETREKIHRKINENTNSRVLLWAIFEACVLIIMSAGQVYYLKRFFEVRRVV 629
            + L SA      +  N ++CF++ I   T   L ++V  GG  D+D ++ DP G++LY  +KK  D FTF    +G YK+CFSN  S+ T+K + F      D      ++   + +++E     + +AL +V   Q +   RE   R   E+ NSRV  W++ EA +L+++S  QV  L+ FF  R+  
Sbjct:   21 VGLSSASELTFELPDNAKQCFYEDITIGTKCTLEFQVVTGGHYDVDCRLEDPEGTVLYKEMKKQYDSFTFSAARNGTYKFCFSNEFSTFTHKTVYFDFQVGDDPPLFPNENRVTALTQMESACVSIHEALKSVMDYQTHFRLREAQGRSRAEDLNSRVAFWSVGEALILLVVSVSQVLLLRSFFSDRKTT 210
[Close]
BLAST of Transmembrane emp24 domain-containing protein vs. Ensembl Xenopus
Match: tmed2 (transmembrane p24 trafficking protein 2 [Source:NCBI gene;Acc:734103])

HSP 1 Score: 213.386 bits (542), Expect = 1.696e-68
Identity = 99/185 (53.51%), Postives = 138/185 (74.59%), Query Frame = 3 
Query:   84 SAFSFFISVSPNVEECFFDRIKPDTDMLLLYEVAEGGSLDIDAKVLDPSGSILYSAVKKSDDKFTFRTKVDGIYKYCFSNTMSSVTNKILMFSLDTI-SPAKKD-SPDSH-SKLEEMVSELDKALTTVKHEQEYMETREKIHRKINENTNSRVLLWAIFEACVLIIMSAGQVYYLKRFFEVRRVV 629
            +A  +F+S+  + EECFF+++   T M L++EVAEGG LDID ++  P    ++   ++S  K+TF   +DG YK+CFSN MS++T KI+MF++D   +P  +D   ++H +KLEEM++EL  A+T VKHEQEYME RE+IHR IN+NTNSRV+LW+ FEA VL+ M+ GQ+YYLKRFFEVRRVV
Sbjct:   17 TASGYFVSIDAHAEECFFEQVTSGTKMGLIFEVAEGGFLDIDVEITGPDNKGIHKGDRESSGKYTFAAHMDGTYKFCFSNRMSTMTPKIVMFTIDIGEAPKGQDMETEAHQNKLEEMINELAVAMTAVKHEQEYMEVRERIHRAINDNTNSRVVLWSFFEALVLVAMTLGQIYYLKRFFEVRRVV 201
[Close]
BLAST of Transmembrane emp24 domain-containing protein vs. Ensembl Xenopus
Match: tmed2 (transmembrane p24 trafficking protein 2 [Source:NCBI gene;Acc:734103])

HSP 1 Score: 213.001 bits (541), Expect = 2.503e-68
Identity = 101/192 (52.60%), Postives = 139/192 (72.40%), Query Frame = 3 
Query:   84 SAFSFFISVSPNVEECFFDRIKPDTDMLLLYEVAEGGSLDIDAKVLDPSGSILYSAVKKSDDKFTFRTKVDGIYKYCFSNTMSSVTNKILMFSLDTI-SPAKKD--------SPDSH-SKLEEMVSELDKALTTVKHEQEYMETREKIHRKINENTNSRVLLWAIFEACVLIIMSAGQVYYLKRFFEVRRVV 629
            +A  +F+S+  + EECFF+++   T M L++EVAEGG LDID ++  P    ++   ++S  K+TF   +DG YK+CFSN MS++T KI+MF++D   +P  +D        S D+H +KLEEM++EL  A+T VKHEQEYME RE+IHR IN+NTNSRV+LW+ FEA VL+ M+ GQ+YYLKRFFEVRRVV
Sbjct:   17 TASGYFVSIDAHAEECFFEQVTSGTKMGLIFEVAEGGFLDIDVEITGPDNKGIHKGDRESSGKYTFAAHMDGTYKFCFSNRMSTMTPKIVMFTIDIGEAPKGQDMETEGIGESWDAHQNKLEEMINELAVAMTAVKHEQEYMEVRERIHRAINDNTNSRVVLWSFFEALVLVAMTLGQIYYLKRFFEVRRVV 208
[Close]
BLAST of Transmembrane emp24 domain-containing protein vs. Ensembl Xenopus
Match: serinc2 (serine incorporator 2 [Source:Xenbase;Acc:XB-GENE-968901])

HSP 1 Score: 115.931 bits (289), Expect = 1.743e-30
Identity = 65/190 (34.21%), Postives = 100/190 (52.63%), Query Frame = 3 
Query:  117 NVEECFFDRIKPDTDMLLLYEVAEGGSLDIDAKVLDPSGSILYSAVKKSDDKFTFRTKVDGIYKYCFSNTMSSVTNKILMFSL----DTISPAKKDSPDSHSKLEEMVSELDKALTTVKHEQEYMETREKIHRKINENTNSRVLLWAIFEACVLIIMSAGQVYYLKRFFEVRRVV*SNSIEITVATIIGS 674
            N ++CF++ I   T   L ++V  GG  D+D ++ DP G +LY  +KK  D FTF    +G YK+CFSN  S+ T+K + F      D      ++   + +++E     + +AL +V   Q +   RE   R   E+ NSRV  W+I EA +L+++S GQV+ LK FF  +R         T  T +GS
Sbjct:   39 NAKQCFYEDITQGTKCTLEFQVITGGHYDVDCRLEDPDGIVLYKEMKKQYDSFTFTATRNGTYKFCFSNEFSTFTHKTVYFDFQVGDDPPLFPNENRATALTQMESSCVSIHEALKSVIDYQTHFRLREAQGRSRAEDLNSRVAYWSIGEAIILLVVSIGQVFLLKSFFSDKR---------TTTTRVGS 219
[Close]
BLAST of Transmembrane emp24 domain-containing protein vs. Ensembl Xenopus
Match: serinc2 (serine incorporator 2 [Source:Xenbase;Acc:XB-GENE-968901])

HSP 1 Score: 115.931 bits (289), Expect = 1.920e-30
Identity = 61/175 (34.86%), Postives = 95/175 (54.29%), Query Frame = 3 
Query:  117 NVEECFFDRIKPDTDMLLLYEVAEGGSLDIDAKVLDPSGSILYSAVKKSDDKFTFRTKVDGIYKYCFSNTMSSVTNKILMFSL----DTISPAKKDSPDSHSKLEEMVSELDKALTTVKHEQEYMETREKIHRKINENTNSRVLLWAIFEACVLIIMSAGQVYYLKRFFEVRRVV 629
            N ++CF++ I   T   L ++V  GG  D+D ++ DP G +LY  +KK  D FTF    +G YK+CFSN  S+ T+K + F      D      ++   + +++E     + +AL +V   Q +   RE   R   E+ NSRV  W+I EA +L+++S GQV+ LK FF  +R  
Sbjct:   45 NAKQCFYEDITQGTKCTLEFQVITGGHYDVDCRLEDPDGIVLYKEMKKQYDSFTFTATRNGTYKFCFSNEFSTFTHKTVYFDFQVGDDPPLFPNENRATALTQMESSCVSIHEALKSVIDYQTHFRLREAQGRSRAEDLNSRVAYWSIGEAIILLVVSIGQVFLLKSFFSDKRTT 219
[Close]
BLAST of Transmembrane emp24 domain-containing protein vs. Ensembl Xenopus
Match: tmed5 (transmembrane p24 trafficking protein 5 [Source:NCBI gene;Acc:549314])

HSP 1 Score: 93.2041 bits (230), Expect = 5.243e-22
Identity = 56/188 (29.79%), Postives = 97/188 (51.60%), Query Frame = 3 
Query:  105 SVSPNVEECFFDRIKPDTDMLLLYEVAEGGSLDIDAKVLDPSGSILYSAVKKSDDKFTFRTKVDGIYKYCFSNTMSSVTNKILMFS--LDTISPAKKDSPDSHS----------KLE---EMVSELDKALTTVKHEQEYMETREKIHRKINENTNSRVLLWAIFEACVLIIMSAGQVYYLKRFFEVRR 623
            ++    +ECFF  +K D  + + Y+V +G  LD+D  +  P+G +L S  ++SD   +  T +DG Y++CF N+ S ++ K++ F   LD ++    +  D  S          KLE   E ++ +   LT     Q  ++  E   R + E+   RV  W++F   V++++SA QVY L+  FE +R
Sbjct:   33 TLPAGQKECFFQPMKRDATLEIEYQVLDGAGLDVDFSLTSPNGELLLSEERQSDGVHSVET-IDGDYQFCFDNSFSRMSEKVIFFELILDHLNDEGNELEDWKSYITGTDLLDMKLEDILETINSVKGRLTKSAQIQTLLKAFEARDRNLQESNFERVTFWSVFNLTVMVVVSALQVYMLRSLFEDKR 219
[Close]
BLAST of Transmembrane emp24 domain-containing protein vs. Ensembl Mouse
Match: Tmed2 (transmembrane p24 trafficking protein 2 [Source:MGI Symbol;Acc:MGI:1929269])

HSP 1 Score: 215.698 bits (548), Expect = 1.463e-69
Identity = 100/182 (54.95%), Postives = 136/182 (74.73%), Query Frame = 3 
Query:   93 SFFISVSPNVEECFFDRIKPDTDMLLLYEVAEGGSLDIDAKVLDPSGSILYSAVKKSDDKFTFRTKVDGIYKYCFSNTMSSVTNKILMFSLDTI-SPAKKD-SPDSH-SKLEEMVSELDKALTTVKHEQEYMETREKIHRKINENTNSRVLLWAIFEACVLIIMSAGQVYYLKRFFEVRRVV 629
             +F+S+  + EECFF+R+   T M L++EVAEGG LDID ++  P    +Y   ++S  K+TF   +DG YK+CFSN MS++T KI+MF++D   +P  +D   ++H +KLEEM++EL  A+T VKHEQEYME RE+IHR IN+NTNSRV+LW+ FEA VL+ M+ GQ+YYLKRFFEVRRVV
Sbjct:   20 GYFVSIDAHAEECFFERVTSGTKMGLIFEVAEGGFLDIDVEITGPDNKGIYKGDRESSGKYTFAAHMDGTYKFCFSNRMSTMTPKIVMFTIDIGEAPKGQDMETEAHQNKLEEMINELAVAMTAVKHEQEYMEVRERIHRAINDNTNSRVVLWSFFEALVLVAMTLGQIYYLKRFFEVRRVV 201
[Close]
BLAST of Transmembrane emp24 domain-containing protein vs. Ensembl Mouse
Match: Tmed2 (transmembrane p24 trafficking protein 2 [Source:MGI Symbol;Acc:MGI:1929269])

HSP 1 Score: 167.548 bits (423), Expect = 4.201e-51
Identity = 79/142 (55.63%), Postives = 107/142 (75.35%), Query Frame = 3 
Query:  213 KVLDPSGSILYSAVKKSDDKFTFRTKVDGIYKYCFSNTMSSVTNKILMFSLDTI-SPAKKD-SPDSH-SKLEEMVSELDKALTTVKHEQEYMETREKIHRKINENTNSRVLLWAIFEACVLIIMSAGQVYYLKRFFEVRRVV 629
            ++  P    +Y   ++S  K+TF   +DG YK+CFSN MS++T KI+MF++D   +P  +D   ++H +KLEEM++EL  A+T VKHEQEYME RE+IHR IN+NTNSRV+LW+ FEA VL+ M+ GQ+YYLKRFFEVRRVV
Sbjct:   35 RITGPDNKGIYKGDRESSGKYTFAAHMDGTYKFCFSNRMSTMTPKIVMFTIDIGEAPKGQDMETEAHQNKLEEMINELAVAMTAVKHEQEYMEVRERIHRAINDNTNSRVVLWSFFEALVLVAMTLGQIYYLKRFFEVRRVV 176
[Close]
BLAST of Transmembrane emp24 domain-containing protein vs. Ensembl Mouse
Match: Tmed2 (transmembrane p24 trafficking protein 2 [Source:MGI Symbol;Acc:MGI:1929269])

HSP 1 Score: 135.191 bits (339), Expect = 1.978e-39
Identity = 69/112 (61.61%), Postives = 86/112 (76.79%), Query Frame = 3 
Query:  327 MSSVTNKILMFSLDTISPAKK----------DSPDSH-SKLEEMVSELDKALTTVKHEQEYMETREKIHRKINENTNSRVLLWAIFEACVLIIMSAGQVYYLKRFFEVRRVV 629
            MS++T KI+MF++D I  A K          DS D+H +KLEEM++EL  A+T VKHEQEYME RE+IHR IN+NTNSRV+LW+ FEA VL+ M+ GQ+YYLKRFFEVRRVV
Sbjct:    2 MSTMTPKIVMFTID-IGEAPKGQDMETEGGGDSWDAHQNKLEEMINELAVAMTAVKHEQEYMEVRERIHRAINDNTNSRVVLWSFFEALVLVAMTLGQIYYLKRFFEVRRVV 112
[Close]
BLAST of Transmembrane emp24 domain-containing protein vs. Ensembl Mouse
Match: Tmed7 (transmembrane p24 trafficking protein 7 [Source:MGI Symbol;Acc:MGI:1913926])

HSP 1 Score: 115.931 bits (289), Expect = 1.559e-30
Identity = 63/175 (36.00%), Postives = 95/175 (54.29%), Query Frame = 3 
Query:  117 NVEECFFDRIKPDTDMLLLYEVAEGGSLDIDAKVLDPSGSILYSAVKKSDDKFTFRTKVDGIYKYCFSNTMSSVTNKILMFSLDTIS-PAKKDSPDSHSKLEEMVS---ELDKALTTVKHEQEYMETREKIHRKINENTNSRVLLWAIFEACVLIIMSAGQVYYLKRFFEVRRVV 629
            N ++CF++ I   T   L ++V  GG  D+D ++ DP G +LY  +KK  D FTF    +G YK+CFSN  S+ T+K + F       P    S +  S L +M S    + +AL +V   Q +   RE   R   E+ N+RV  W++ EA +L+++S GQV+ LK FF  +R  
Sbjct:   44 NAKQCFYEDITQGTKCTLEFQVITGGHYDVDCRLEDPDGKVLYKEMKKQYDSFTFTASRNGTYKFCFSNEFSTFTHKTVYFDFQVGEDPPLFPSENRVSALTQMESACVSIHEALKSVIDYQTHFRLREAQGRSRAEDLNTRVAYWSVGEALILLVVSVGQVFLLKSFFSDKRTT 218
[Close]
BLAST of Transmembrane emp24 domain-containing protein vs. Ensembl Mouse
Match: Tmed3 (transmembrane p24 trafficking protein 3 [Source:MGI Symbol;Acc:MGI:1913361])

HSP 1 Score: 109.383 bits (272), Expect = 4.078e-28
Identity = 58/176 (32.95%), Postives = 92/176 (52.27%), Query Frame = 3 
Query:  117 NVEECFFDRIKPDTDMLLLYEVAEGGSLDIDAKVLDPSGSILYSAVKKSDDKFTFRTKVDGIYKYCFSNTMSSVTNKILMFSLDT-----ISPAKKDSPDSHSKLEEMVSELDKALTTVKHEQEYMETREKIHRKINENTNSRVLLWAIFEACVLIIMSAGQVYYLKRFFEVRRVV 629
            N ++CF + ++      L Y+V  GG  D+D  V DP G+++Y   KK  D FT++T+  G+Y++CFSN  S+ ++K + F         I P   +   + +++E     + +AL TV   Q +   RE   R   E+ NSRV  W++ E   L ++S  QV  LK FF  +R V
Sbjct:   40 NAKQCFHEEVEQGVKFSLDYQVITGGHYDVDCYVEDPRGNVIYRETKKQYDSFTYKTEAKGVYRFCFSNEFSTFSHKTVYFDFQVGDEPPILPDMGNRVTALTQMESACVTIHEALKTVIDSQTHYRLREAQDRARAEDLNSRVSYWSVGETIALFVVSFSQVLLLKSFFTEKRPV 215
[Close]
BLAST of Transmembrane emp24 domain-containing protein vs. UniProt/SwissProt
Match: sp|A7SXK3|TMED_NEMVE (Transmembrane emp24 domain-containing protein OS=Nematostella vectensis OX=45351 GN=v1g194562 PE=3 SV=1)

HSP 1 Score: 221.861 bits (564), Expect = 4.093e-71
Identity = 105/193 (54.40%), Postives = 138/193 (71.50%), Query Frame = 3 
Query:   63 VLFILLHSAFSFFISVSPNVEECFFDRIKPDTDMLLLYEVAEGGSLDIDAKVLDPSGSILYSAVKKSDDKFTFRTKVDGIYKYCFSNTMSSVTNKILMFSLDTISPAKKDSPD----SHSKLEEMVSELDKALTTVKHEQEYMETREKIHRKINENTNSRVLLWAIFEACVLIIMSAGQVYYLKRFFEVRRVV 629
            VL  L  S+  +FI++  + EECF D++   T M L++EVAEGG LDID K++ P   ++YS  +++  K+TF   +DG Y YCFSN MS++T K+L FS+D I  A KD+       H KL EMVS+L +A+T VKHEQEYME RE+IHR IN+NTNSRV+ W+ FE+ VL+ M+ GQVYYLKRFFEVRRVV
Sbjct:   12 VLMFLARSSLCYFITIDAHGEECFHDKVTSGTKMGLIFEVAEGGFLDIDVKIIGPDQKVIYSGERETSGKYTFAAHMDGTYNYCFSNKMSTMTPKVLKFSMD-IGEAPKDTSKEDNAGHDKLSEMVSQLSEAMTGVKHEQEYMEVRERIHRSINDNTNSRVVWWSFFESLVLVAMTLGQVYYLKRFFEVRRVV 203
[Close]
BLAST of Transmembrane emp24 domain-containing protein vs. UniProt/SwissProt
Match: sp|P49020|TMED2_CRIGR (Transmembrane emp24 domain-containing protein 2 (Fragment) OS=Cricetulus griseus OX=10029 GN=TMED2 PE=1 SV=1)

HSP 1 Score: 216.468 bits (550), Expect = 3.977e-69
Identity = 101/185 (54.59%), Postives = 138/185 (74.59%), Query Frame = 3 
Query:   84 SAFSFFISVSPNVEECFFDRIKPDTDMLLLYEVAEGGSLDIDAKVLDPSGSILYSAVKKSDDKFTFRTKVDGIYKYCFSNTMSSVTNKILMFSLDTI-SPAKKD-SPDSH-SKLEEMVSELDKALTTVKHEQEYMETREKIHRKINENTNSRVLLWAIFEACVLIIMSAGQVYYLKRFFEVRRVV 629
            +A  +F+S+  + EECFF+R+   T M L++EVAEGG LDID ++  P    +Y   ++S  K+TF   +DG YK+CFSN MS++T KI+MF++D   +P  +D   ++H +KLEEM++EL  A+T VKHEQEYME RE+IHR IN+NTNSRV+LW+ FEA VL+ M+ GQ+YYLKRFFEVRRVV
Sbjct:   12 TASGYFVSIDAHAEECFFERVTSGTKMGLIFEVAEGGFLDIDVEITGPDNKGIYKGDRESSGKYTFAAHMDGTYKFCFSNRMSTMTPKIVMFTIDIGEAPKGQDMETEAHQNKLEEMINELAVAMTAVKHEQEYMEVRERIHRAINDNTNSRVVLWSFFEALVLVAMTLGQIYYLKRFFEVRRVV 196
[Close]
BLAST of Transmembrane emp24 domain-containing protein vs. UniProt/SwissProt
Match: sp|Q63524|TMED2_RAT (Transmembrane emp24 domain-containing protein 2 OS=Rattus norvegicus OX=10116 GN=Tmed2 PE=1 SV=1)

HSP 1 Score: 215.698 bits (548), Expect = 9.691e-69
Identity = 100/182 (54.95%), Postives = 136/182 (74.73%), Query Frame = 3 
Query:   93 SFFISVSPNVEECFFDRIKPDTDMLLLYEVAEGGSLDIDAKVLDPSGSILYSAVKKSDDKFTFRTKVDGIYKYCFSNTMSSVTNKILMFSLDTI-SPAKKD-SPDSH-SKLEEMVSELDKALTTVKHEQEYMETREKIHRKINENTNSRVLLWAIFEACVLIIMSAGQVYYLKRFFEVRRVV 629
             +F+S+  + EECFF+R+   T M L++EVAEGG LDID ++  P    +Y   ++S  K+TF   +DG YK+CFSN MS++T KI+MF++D   +P  +D   ++H +KLEEM++EL  A+T VKHEQEYME RE+IHR IN+NTNSRV+LW+ FEA VL+ M+ GQ+YYLKRFFEVRRVV
Sbjct:   20 GYFVSIDAHAEECFFERVTSGTKMGLIFEVAEGGFLDIDVEITGPDNKGIYKGDRESSGKYTFAAHMDGTYKFCFSNRMSTMTPKIVMFTIDIGEAPKGQDMETEAHQNKLEEMINELAVAMTAVKHEQEYMEVRERIHRAINDNTNSRVVLWSFFEALVLVAMTLGQIYYLKRFFEVRRVV 201
[Close]
BLAST of Transmembrane emp24 domain-containing protein vs. UniProt/SwissProt
Match: sp|Q15363|TMED2_HUMAN (Transmembrane emp24 domain-containing protein 2 OS=Homo sapiens OX=9606 GN=TMED2 PE=1 SV=1)

HSP 1 Score: 215.698 bits (548), Expect = 9.691e-69
Identity = 100/182 (54.95%), Postives = 136/182 (74.73%), Query Frame = 3 
Query:   93 SFFISVSPNVEECFFDRIKPDTDMLLLYEVAEGGSLDIDAKVLDPSGSILYSAVKKSDDKFTFRTKVDGIYKYCFSNTMSSVTNKILMFSLDTI-SPAKKD-SPDSH-SKLEEMVSELDKALTTVKHEQEYMETREKIHRKINENTNSRVLLWAIFEACVLIIMSAGQVYYLKRFFEVRRVV 629
             +F+S+  + EECFF+R+   T M L++EVAEGG LDID ++  P    +Y   ++S  K+TF   +DG YK+CFSN MS++T KI+MF++D   +P  +D   ++H +KLEEM++EL  A+T VKHEQEYME RE+IHR IN+NTNSRV+LW+ FEA VL+ M+ GQ+YYLKRFFEVRRVV
Sbjct:   20 GYFVSIDAHAEECFFERVTSGTKMGLIFEVAEGGFLDIDVEITGPDNKGIYKGDRESSGKYTFAAHMDGTYKFCFSNRMSTMTPKIVMFTIDIGEAPKGQDMETEAHQNKLEEMINELAVAMTAVKHEQEYMEVRERIHRAINDNTNSRVVLWSFFEALVLVAMTLGQIYYLKRFFEVRRVV 201
[Close]
BLAST of Transmembrane emp24 domain-containing protein vs. UniProt/SwissProt
Match: sp|Q9R0Q3|TMED2_MOUSE (Transmembrane emp24 domain-containing protein 2 OS=Mus musculus OX=10090 GN=Tmed2 PE=1 SV=1)

HSP 1 Score: 215.698 bits (548), Expect = 1.023e-68
Identity = 100/182 (54.95%), Postives = 136/182 (74.73%), Query Frame = 3 
Query:   93 SFFISVSPNVEECFFDRIKPDTDMLLLYEVAEGGSLDIDAKVLDPSGSILYSAVKKSDDKFTFRTKVDGIYKYCFSNTMSSVTNKILMFSLDTI-SPAKKD-SPDSH-SKLEEMVSELDKALTTVKHEQEYMETREKIHRKINENTNSRVLLWAIFEACVLIIMSAGQVYYLKRFFEVRRVV 629
             +F+S+  + EECFF+R+   T M L++EVAEGG LDID ++  P    +Y   ++S  K+TF   +DG YK+CFSN MS++T KI+MF++D   +P  +D   ++H +KLEEM++EL  A+T VKHEQEYME RE+IHR IN+NTNSRV+LW+ FEA VL+ M+ GQ+YYLKRFFEVRRVV
Sbjct:   20 GYFVSIDAHAEECFFERVTSGTKMGLIFEVAEGGFLDIDVEITGPDNKGIYKGDRESSGKYTFAAHMDGTYKFCFSNRMSTMTPKIVMFTIDIGEAPKGQDMETEAHQNKLEEMINELAVAMTAVKHEQEYMEVRERIHRAINDNTNSRVVLWSFFEALVLVAMTLGQIYYLKRFFEVRRVV 201
[Close]
BLAST of Transmembrane emp24 domain-containing protein vs. TrEMBL
Match: A0A2I9LNU4 (Cargo transport protein OS=Centruroides hentzi OX=88313 PE=3 SV=1)

HSP 1 Score: 234.572 bits (597), Expect = 1.600e-73
Identity = 108/196 (55.10%), Postives = 148/196 (75.51%), Query Frame = 3 
Query:   60 CVLFILLHSAFS--FFISVSPNVEECFFDRIKPDTDMLLLYEVAEGGSLDIDAKVLDPSGSILYSAVKKSDDKFTFRTKVDGIYKYCFSNTMSSVTNKILMFSLDTISPAK----KDSPDSHSKLEEMVSELDKALTTVKHEQEYMETREKIHRKINENTNSRVLLWAIFEACVLIIMSAGQVYYLKRFFEVRRVV 629
            C+L + L   FS  +F++V  + EECFF+R+K DT M L++EVAEGG LDID K+  P   ++Y   ++S+ K+TF   +DG+Y YCFSN MS++T K++MFS++   P K    K+S  +H+KLEEM+ EL  +LT+VKHEQEYM  R++IHR+INE+TNSRV+LWA+FEA VL+ ++ GQVYYLKRFFEVRRVV
Sbjct:   11 CLLMVTLFLNFSECYFVTVGAHTEECFFERVKADTKMGLIFEVAEGGFLDIDVKITGPDEKVIYKGERESNGKYTFSAHMDGVYSYCFSNAMSTMTPKVIMFSMEIGDPPKAAQDKESEATHNKLEEMIKELSTSLTSVKHEQEYMAVRDRIHREINESTNSRVVLWALFEAGVLVCLTLGQVYYLKRFFEVRRVV 206
[Close]
BLAST of Transmembrane emp24 domain-containing protein vs. TrEMBL
Match: A0A1W7RAL9 (Transmembrane emp24 domain-containing protein 2 OS=Hadrurus spadix OX=141984 PE=3 SV=1)

HSP 1 Score: 234.187 bits (596), Expect = 1.652e-73
Identity = 107/196 (54.59%), Postives = 147/196 (75.00%), Query Frame = 3 
Query:   54 IFCVLFILLHSAFSFFISVSPNVEECFFDRIKPDTDMLLLYEVAEGGSLDIDAKVLDPSGSILYSAVKKSDDKFTFRTKVDGIYKYCFSNTMSSVTNKILMFSLDTISPAK----KDSPDSHSKLEEMVSELDKALTTVKHEQEYMETREKIHRKINENTNSRVLLWAIFEACVLIIMSAGQVYYLKRFFEVRRVV 629
            IF +L      ++ +F++V  + EECFF+R+K DT M L++EVAEGG LDID K++ P   ++Y   ++S+ K+TF   +DG+Y YCFSN MS++T K++MFS++   P K    K++  SH+KLEEM+ EL  +LT+VKHEQEYM  R++IHR+INE+TNSRV+LWA FEA VL+ M+ GQVYYLKRFFEVRRVV
Sbjct:    9 IFILLLTCSKVSYCYFVTVGAHTEECFFERVKADTKMGLIFEVAEGGFLDIDVKIVGPDEKVVYKGERESNGKYTFSAHMDGVYTYCFSNAMSTMTPKVIMFSIEIGDPPKANQDKENEASHNKLEEMIKELSTSLTSVKHEQEYMAVRDRIHREINESTNSRVVLWAFFEATVLVAMTLGQVYYLKRFFEVRRVV 204
[Close]
BLAST of Transmembrane emp24 domain-containing protein vs. TrEMBL
Match: A0A0N4VI97 (GOLD domain-containing protein OS=Enterobius vermicularis OX=51028 GN=EVEC_LOCUS9893 PE=3 SV=1)

HSP 1 Score: 233.417 bits (594), Expect = 3.903e-73
Identity = 109/200 (54.50%), Postives = 142/200 (71.00%), Query Frame = 3 
Query:   57 FCVLFILLHSAFS-FFISVSPNVEECFFDRIKPDTDMLLLYEVAEGGSLDIDAKVLDPSGSILYSAVKKSDDKFTFRTKVDGIYKYCFSNTMSSVTNKILMFSLDTISP--------AKKDSPDSHSKLEEMVSELDKALTTVKHEQEYMETREKIHRKINENTNSRVLLWAIFEACVLIIMSAGQVYYLKRFFEVRRVV 629
            FC+    L S+ S +FI +  N E+CFFDR+   T M L++EVAEGG LDID K+  P  +++Y   ++S  K+TF   +DG+Y YCF N MS++T K++MFS++ I P        A  +  +S +KLEEM+ EL  ALT VKHEQEYME RE++HR INENTNSRV+LWA+FEA VL+ M+ GQVYYLKRFFEVRRVV
Sbjct:    5 FCLAVAALFSSTSAYFIHIDANEEQCFFDRVVSGTKMGLMFEVAEGGFLDIDVKITGPDNNVIYKGERESSGKYTFGAHMDGVYTYCFGNQMSTMTPKVVMFSMEVIPPGAPAGTGDASPNPSESGAKLEEMIRELSTALTAVKHEQEYMEVRERVHRSINENTNSRVVLWAVFEALVLVSMAVGQVYYLKRFFEVRRVV 204
[Close]
BLAST of Transmembrane emp24 domain-containing protein vs. TrEMBL
Match: C3XVK2 (GOLD domain-containing protein OS=Branchiostoma floridae OX=7739 GN=BRAFLDRAFT_127851 PE=3 SV=1)

HSP 1 Score: 231.876 bits (590), Expect = 1.554e-72
Identity = 110/195 (56.41%), Postives = 147/195 (75.38%), Query Frame = 3 
Query:   54 IFCVLFILLHSAFSFFISVSPNVEECFFDRIKPDTDMLLLYEVAEGGSLDIDAKVLDPSGSILYSAVKKSDDKFTFRTKVDGIYKYCFSNTMSSVTNKILMFSLDTI-SPAKKD-SPDSH-SKLEEMVSELDKALTTVKHEQEYMETREKIHRKINENTNSRVLLWAIFEACVLIIMSAGQVYYLKRFFEVRRVV 629
            +  VL   L S  ++F+SV  + EECFFD++   T M L++EVAEGG LDID K+  P  +++YS  ++S+ K+TF   +DG+YKYCFSN MS++T KI+MFS+D   +P  +D   ++H +KLEEM++EL  ALT VKHEQEYME RE+IHR IN+NTNSRV+LW+ FEA VL+ M+ GQ+YYLKRFFEVRRVV
Sbjct:    9 LLAVLAACLDSISAYFVSVDAHAEECFFDKVTSGTKMGLMFEVAEGGFLDIDVKITGPDSTVIYSGERESNGKYTFAAHMDGVYKYCFSNKMSTMTPKIVMFSMDIGEAPKGQDMETEAHQNKLEEMINELAVALTGVKHEQEYMEVRERIHRAINDNTNSRVVLWSFFEALVLVAMTLGQIYYLKRFFEVRRVV 203
[Close]
BLAST of Transmembrane emp24 domain-containing protein vs. TrEMBL
Match: A0A0N5AML7 (GOLD domain-containing protein OS=Syphacia muris OX=451379 PE=3 SV=1)

HSP 1 Score: 231.876 bits (590), Expect = 1.752e-72
Identity = 107/194 (55.15%), Postives = 139/194 (71.65%), Query Frame = 3 
Query:   72 ILLHSAFSFFISVSPNVEECFFDRIKPDTDMLLLYEVAEGGSLDIDAKVLDPSGSILYSAVKKSDDKFTFRTKVDGIYKYCFSNTMSSVTNKILMFSLDTISPAKKDS-----PD---SHSKLEEMVSELDKALTTVKHEQEYMETREKIHRKINENTNSRVLLWAIFEACVLIIMSAGQVYYLKRFFEVRRVV 629
            +LL SA +FFI +  N E+CFFDR+   T M L++EV EGG LDID K+  P   ++Y+  ++S  K+TF   +DG+Y YCF N MS++T K++MF+++ + P  + S     PD   S +KLEEMV EL  AL+ VK EQEYME RE++HR INENTNSRV+LW IFEA VL+ M+ GQVYYLKRFFEVRRVV
Sbjct:   11 VLLSSASAFFIHIDANEEQCFFDRVVSGTKMGLMFEVVEGGFLDIDVKISGPDNKVIYNGERESSGKYTFAAHMDGVYTYCFGNQMSTMTPKVVMFTMEVVPPGTQGSENEASPDPSESSAKLEEMVRELSTALSAVKQEQEYMEVRERVHRAINENTNSRVVLWVIFEAIVLVTMTVGQVYYLKRFFEVRRVV 204
[Close]
BLAST of Transmembrane emp24 domain-containing protein vs. Ensembl Cavefish
Match: TMED2 (transmembrane emp24 domain-containing protein 2 [Source:NCBI gene;Acc:103022411])

HSP 1 Score: 217.624 bits (553), Expect = 2.590e-70
Identity = 102/203 (50.25%), Postives = 142/203 (69.95%), Query Frame = 3 
Query:   51 KIFCVLFILLHSAFSFFISVSPNVEECFFDRIKPDTDMLLLYEVAEGGSLDIDAKVLDPSGSILYSAVKKSDDKFTFRTKVDGIYKYCFSNTMSSVTNKILMFSLDTISPAKKD---------SPDSH-SKLEEMVSELDKALTTVKHEQEYMETREKIHRKINENTNSRVLLWAIFEACVLIIMSAGQVYYLKRFFEVRRVV 629
            ++  ++  L  +A  +F+SV  + EECF++R+   T M L++EVAEGG LDID ++  P G  +Y   ++S  K++    +DG YK+CFSN MS++T KI+MF++D     K D         + D+H +KLEEM++EL  A+T VKHEQEYME RE+IHR IN+NTNSRV+LW+ FEA VL+ M+ GQ+YYLKRFFEVRRVV
Sbjct:    6 ELMVLMAALSATASGYFVSVDAHAEECFYERVNSGTKMGLMFEVAEGGFLDIDVEITGPDGKQIYKGDRESSGKYSVAAHMDGTYKFCFSNKMSTMTPKIVMFTIDIGEAPKGDGMETEVGGGTWDAHQNKLEEMINELAVAMTAVKHEQEYMEVRERIHRAINDNTNSRVVLWSFFEALVLVAMTLGQIYYLKRFFEVRRVV 208
[Close]
BLAST of Transmembrane emp24 domain-containing protein vs. Ensembl Cavefish
Match: TMED2 (transmembrane emp24 domain-containing protein 2 [Source:NCBI gene;Acc:103022411])

HSP 1 Score: 217.624 bits (553), Expect = 2.590e-70
Identity = 102/203 (50.25%), Postives = 142/203 (69.95%), Query Frame = 3 
Query:   51 KIFCVLFILLHSAFSFFISVSPNVEECFFDRIKPDTDMLLLYEVAEGGSLDIDAKVLDPSGSILYSAVKKSDDKFTFRTKVDGIYKYCFSNTMSSVTNKILMFSLDTISPAKKD---------SPDSH-SKLEEMVSELDKALTTVKHEQEYMETREKIHRKINENTNSRVLLWAIFEACVLIIMSAGQVYYLKRFFEVRRVV 629
            ++  ++  L  +A  +F+SV  + EECF++R+   T M L++EVAEGG LDID ++  P G  +Y   ++S  K++    +DG YK+CFSN MS++T KI+MF++D     K D         + D+H +KLEEM++EL  A+T VKHEQEYME RE+IHR IN+NTNSRV+LW+ FEA VL+ M+ GQ+YYLKRFFEVRRVV
Sbjct:    6 ELMVLMAALSATASGYFVSVDAHAEECFYERVNSGTKMGLMFEVAEGGFLDIDVEITGPDGKQIYKGDRESSGKYSVAAHMDGTYKFCFSNKMSTMTPKIVMFTIDIGEAPKGDGMETEVGGGTWDAHQNKLEEMINELAVAMTAVKHEQEYMEVRERIHRAINDNTNSRVVLWSFFEALVLVAMTLGQIYYLKRFFEVRRVV 208
[Close]
BLAST of Transmembrane emp24 domain-containing protein vs. Ensembl Cavefish
Match: TMED2 (transmembrane emp24 domain-containing protein 2 [Source:NCBI gene;Acc:103022411])

HSP 1 Score: 215.698 bits (548), Expect = 1.409e-69
Identity = 100/205 (48.78%), Postives = 140/205 (68.29%), Query Frame = 3 
Query:   51 KIFCVLFILLHSAFSFFISVSPNVEECFFDRIKPDTDMLLLYEVAEGGSLDIDAKVLDPSGSILYSAVKKSDDKFTFRTKVDGIYKYCFSNTMSSVTNKILMFSLDTISPAKKDSPDS------------HSKLEEMVSELDKALTTVKHEQEYMETREKIHRKINENTNSRVLLWAIFEACVLIIMSAGQVYYLKRFFEVRRVV 629
            ++  ++  L  +A  +F+SV  + EECF++R+   T M L++EVAEGG LDID ++  P G  +Y   ++S  K++    +DG YK+CFSN MS++T KI+MF++D     K D  ++             +KLEEM++EL  A+T VKHEQEYME RE+IHR IN+NTNSRV+LW+ FEA VL+ M+ GQ+YYLKRFFEVRRVV
Sbjct:    6 ELMVLMAALSATASGYFVSVDAHAEECFYERVNSGTKMGLMFEVAEGGFLDIDVEITGPDGKQIYKGDRESSGKYSVAAHMDGTYKFCFSNKMSTMTPKIVMFTIDIGEAPKGDGMETEGMIGDCSVTAHQNKLEEMINELAVAMTAVKHEQEYMEVRERIHRAINDNTNSRVVLWSFFEALVLVAMTLGQIYYLKRFFEVRRVV 210
[Close]
BLAST of Transmembrane emp24 domain-containing protein vs. Ensembl Cavefish
Match: tmed2 (transmembrane emp24 domain-containing protein 2 [Source:NCBI gene;Acc:111194998])

HSP 1 Score: 214.157 bits (544), Expect = 5.372e-69
Identity = 99/182 (54.40%), Postives = 136/182 (74.73%), Query Frame = 3 
Query:   93 SFFISVSPNVEECFFDRIKPDTDMLLLYEVAEGGSLDIDAKVLDPSGSILYSAVKKSDDKFTFRTKVDGIYKYCFSNTMSSVTNKILMFSLDTI-SPAKKD-SPDSH-SKLEEMVSELDKALTTVKHEQEYMETREKIHRKINENTNSRVLLWAIFEACVLIIMSAGQVYYLKRFFEVRRVV 629
             +F+SV  + EECF++R+   T M L++EVAEGG LDID ++  P G  +Y   ++S  K++    +DG YK+CFSN MS++T KI+MF++D   +P  +D   ++H +KLEEM++EL  A+T VKHEQEYME RE+IHR IN+NTNSRV+LW+ FEA VL+ M+ GQ+YYLKRFFEVRRVV
Sbjct:   21 GYFVSVDAHAEECFYERVNSGTKMGLMFEVAEGGFLDIDVEITGPDGKQIYKGDRESSGKYSVAAHMDGTYKFCFSNKMSTMTPKIVMFTIDIGEAPKGQDMETEAHQNKLEEMINELAVAMTAVKHEQEYMEVRERIHRAINDNTNSRVVLWSFFEALVLVAMTLGQIYYLKRFFEVRRVV 202
[Close]
BLAST of Transmembrane emp24 domain-containing protein vs. Ensembl Cavefish
Match: tmed7 (transmembrane p24 trafficking protein 7 [Source:ZFIN;Acc:ZDB-GENE-040426-2570])

HSP 1 Score: 108.612 bits (270), Expect = 5.110e-28
Identity = 58/179 (32.40%), Postives = 94/179 (52.51%), Query Frame = 3 
Query:  117 NVEECFFDRIKPDTDMLLLYEVAEGGSLDIDAKVLDPSGSILYSAVKKSDDKFTFRTKVDGIYKYCFSNTMSSVTNKILMFSLDTISPAKKDSP--------DSHSKLEEMVSELDKALTTVKHEQEYMETREKIHRKINENTNSRVLLWAIFEACVLIIMSAGQVYYLKRFFEVRRVV 629
            N ++CF++ I   T   L ++V  GG  D+D ++ DP G++LY  +KK  D FTF    +G YK+CFSN  S+ T+K + F         +D P         + +++E     + +AL +V   Q +   RE   R   E+ N+RV  W+I EA +L+++S  QV  L+ FF  ++  
Sbjct:   40 NAKQCFYEDITIGTKCTLEFQVVTGGHYDVDCRLEDPDGTVLYKEMKKQYDSFTFTAAKNGTYKFCFSNEFSTFTHKTVYFDFQ----VGEDPPLFPNENRVTALTQMESACVSIHEALKSVIDYQTHFRLREAQGRSRAEDLNTRVAFWSIGEAFILLVVSISQVVLLRSFFSDKKTT 214
[Close]
BLAST of Transmembrane emp24 domain-containing protein vs. Ensembl Sea Lamprey
Match: tmed2 (transmembrane p24 trafficking protein 2 [Source:ZFIN;Acc:ZDB-GENE-030131-269])

HSP 1 Score: 171.785 bits (434), Expect = 6.555e-54
Identity = 78/142 (54.93%), Postives = 109/142 (76.76%), Query Frame = 3 
Query:  213 KVLDPSGSILYSAVKKSDDKFTFRTKVDGIYKYCFSNTMSSVTNKILMFSLDTI-SPAKKD-SPDSH-SKLEEMVSELDKALTTVKHEQEYMETREKIHRKINENTNSRVLLWAIFEACVLIIMSAGQVYYLKRFFEVRRVV 629
            ++  P G  +Y   ++S+ K+TF   +DG+YK+CF N MS++T K++MF++D   +P  +D   ++H +KLEEM++EL  A+T VKHEQEYME RE+IHR +N+NTNSRV+LWA FEA VL+ M+ GQ+YYLKRFFEVRRVV
Sbjct:    2 QITGPDGREIYRGDRESNGKYTFAAHMDGVYKFCFGNKMSTMTPKMVMFTIDMGETPKGQDMETEAHQNKLEEMINELATAMTAVKHEQEYMEVRERIHRSVNDNTNSRVVLWAFFEALVLVAMTLGQIYYLKRFFEVRRVV 143
[Close]
BLAST of Transmembrane emp24 domain-containing protein vs. Ensembl Sea Lamprey
Match: tmed3 (transmembrane p24 trafficking protein 3 [Source:ZFIN;Acc:ZDB-GENE-030131-8335])

HSP 1 Score: 95.9005 bits (237), Expect = 9.124e-24
Identity = 55/170 (32.35%), Postives = 89/170 (52.35%), Query Frame = 3 
Query:  117 NVEECFFDRIKPDTDMLLLYEVAEGGSLDIDAKVLDPSGSILYSAVKKSDDKFTFRTKVDGIYKYCFSNTMSSVTNKILMFSLDTI--SPAKKDSPDSHSKLEEMVSE---LDKALTTVKHEQEYMETREKIHRKINENTNSRVLLWAIFEACVLIIMSAGQVYYLKRFF 611
            N ++CF++ I     + L ++V  GG+ D+D +V  P  S+LY+  +K  D + + T+  G Y+ CFSN  S+ T+K + F L     +P  +D       L +M S    + + L +V + Q     +E   R   E  NSRV +W+I E  +L+++  GQV  LK FF
Sbjct:   52 NAKQCFYEDIDQGVKVTLDFQVITGGNYDVDCRVKGPHDSVLYNENRKQYDSYAWTTEQRGTYEICFSNEFSTFTHKTVYFDLQVGEEAPLFRDEGTRVVALTQMESACVTIHEGLKSVDNYQTQHRLQETQDRHQAEVLNSRVNMWSIGETIILVVVGVGQVMLLKSFF 221
[Close]
BLAST of Transmembrane emp24 domain-containing protein vs. Ensembl Sea Lamprey
Match: tmed5 (transmembrane p24 trafficking protein 5 [Source:ZFIN;Acc:ZDB-GENE-040426-1302])

HSP 1 Score: 94.7449 bits (234), Expect = 2.653e-23
Identity = 61/190 (32.11%), Postives = 103/190 (54.21%), Query Frame = 3 
Query:  105 SVSPNVEECFFDRIKPDTDMLLLYEVAEGGSLDIDAKVLDPSGSILYSAVKKSDDKFTFRTKVDGIYKYCFSNTMSSVTNKILMFS--LDTISPAKKDSP---DSHS-------KLEEMVSELD--KALTTVKHE-QEYMETREKIHRKINENTNSRVLLWAIFEACVLIIMSAGQVYYLKRFFEVRRVV 629
            S++P   ECF+  +KP T + + Y+V +GG LD+D  V  PSG++L +  ++ D   +   K +G Y+ CF N+ S ++ K++ F   LD + P +++ P   D+ S       KLE++   L+  KA  +  H+ Q  +   E   R + E+  +RV LW+      L+ +SA QVY ++  FE +R V
Sbjct:   42 SLAPGHRECFYQPVKPGTVVEIEYQVIDGGELDVDFTVTAPSGTVLLAEHRQGDGVHSVDVKEEGDYEICFDNSFSHISEKLIFFEILLDHMQP-EEERPEWMDAISADHLIGMKLEDLQESLNSVKARLSRSHQIQTVLRAFEARDRNLQESNLARVNLWSAASVLALMGVSALQVYLVRSLFEDKRRV 230
[Close]
BLAST of Transmembrane emp24 domain-containing protein vs. Ensembl Sea Lamprey
Match: tmed7 (transmembrane p24 trafficking protein 7 [Source:ZFIN;Acc:ZDB-GENE-040426-2570])

HSP 1 Score: 91.2781 bits (225), Expect = 3.252e-22
Identity = 58/197 (29.44%), Postives = 93/197 (47.21%), Query Frame = 3 
Query:   51 KIFCVLFILLHSAF-----SFFISVSPNVEECFFDRIKPDTDMLLLYEVAEGGSLDIDAKVLDPSGSILYSAVKKSDDKFTFRTKVDGIYKYCFSNTMSSVTNKILMFSLDT-----ISPAKKDSPDSHSKLEEMVSELDKALTTVKHEQEYMETREKIHRKINENTNSRVLLWAIFEACVLIIMSAGQVYYLKRFF 611
            +++  LF +L S F     +  + +      C F  IK        ++V  GG+ D+D +V  PSG ILY  ++K  D   +  +  GIY  CFSN  S+ ++K + F         +  A  +   S +++E     + +AL +V   Q +    E   R   E+ NSRV LW++ E  +L+ +  GQV  LK FF
Sbjct:   10 RLWYFLFTVLRSCFCVKSCTAHLGLPAQQCRCLFMPIKVGRTCSKEWQVITGGNYDVDCRVEGPSGEILYKEMRKQYDSHVWTAEKKGIYAICFSNEFSTFSHKTVYFDWQIGDEKPVGKASTNGAVSLTQMESACVTIHEALKSVISYQTHHRLEEAQDRYQAEHLNSRVTLWSVGETLMLLSVVVGQVMLLKSFF 206
[Close]
BLAST of Transmembrane emp24 domain-containing protein vs. Ensembl Sea Lamprey
Match: tmed5 (transmembrane p24 trafficking protein 5 [Source:ZFIN;Acc:ZDB-GENE-040426-1302])

HSP 1 Score: 86.6557 bits (213), Expect = 1.808e-20
Identity = 54/193 (27.98%), Postives = 89/193 (46.11%), Query Frame = 3 
Query:   96 FFISVSPNVEECFFDRIKPDTDMLLLYEVAEGGSLDIDAKVLDPSGSILYSAVKKSDDKFTFRTKVDGIYKYCFSNTMSSVTNKILMFS--LDTISPAKKDSPDSHS----------KLEEMVSELDKALTTVKHE---QEYMETREKIHRKINENTNSRVLLWAIFEACVLIIMSAGQVYYLKRFFEVRRVV 629
            F  S+     ECF+  +     M + Y+V +G  +D+D  +  P+G +L++  +KS+   +   K DG Y +CF N+ S V+ K++ F   LD +   K D P              KLE++   +D   T +      Q  +   E   RK+ E     V LW+     VL++++  QVY L+  F  +R V
Sbjct:   30 FTFSLPAGRTECFYQALTAGASMEVEYQVIDGAGMDVDFSISSPTGQVLFAEYRKSEGLQSVEAKQDGDYMFCFDNSFSHVSEKVVFFEVILDNMEVEKDDKPAWKDFVEVDEIIDMKLEDLQETMDNIKTRLGKSIQMQSVLRVYEARDRKLQETNFEMVNLWSGISMVVLVMVAGLQVYTLRSLFNDQRRV 222
[Close]
BLAST of Transmembrane emp24 domain-containing protein vs. Ensembl Yeast
Match: EMP24 (Component of the p24 complex; role in misfolded protein quality control; binds to GPI anchor proteins and mediates their efficient transport from the ER to the Golgi; integral membrane protein that associates with endoplasmic reticulum-derived COPII-coated vesicles [Source:SGD;Acc:S000003168])

HSP 1 Score: 89.3521 bits (220), Expect = 6.790e-22
Identity = 59/203 (29.06%), Postives = 99/203 (48.77%), Query Frame = 3 
Query:   57 FCVLFILLHSAFSFFISVSPNV------EECFFDRIKPDTDMLLLYEVAE-----GGSLDIDAKVLDPS-GSILYSAVKKSDDKFTFRTKVDGIYKYCFSNTMSSVTNKILMFSLDTISPAKKDSPDSHSKLEEMVSELDKALTTVKHEQEYMETREKIHRKINENTNSRVLLWAIFEACVLIIMSAGQVYYLKRFFEVRRVV 629
            F   F++  + F FF + + NV        CFF+ +    ++ + ++  +        L  D  +  P    +L +    S  + T      G ++YCF N  + +  K + F++  +     D P++++ L+  V +L K    VK EQ Y+  RE+ HR   E+TN RV  W+IF+  V+I  S  Q+YYL+RFFEV  +V
Sbjct:    4 FATKFVI--ACFLFFSASAHNVLLPAYGRRCFFEDLSKGDELSISFQFGDRNPQSSSQLTGDFIIYGPERHEVLKTVRDTSHGEITLSAPYKGHFQYCFLNENTGIETKDVTFNIHGVVYVDLDDPNTNT-LDSAVRKLSKLTREVKDEQSYIVIRERTHRNTAESTNDRVKWWSIFQLGVVIANSLFQIYYLRRFFEVTSLV 203
[Close]
BLAST of Transmembrane emp24 domain-containing protein vs. Ensembl Yeast
Match: ERP4 (Member of the p24 family involved in ER to Golgi transport; similar to Emp24p and Erv25p; ERP4 has a paralog, ERP2, that arose from the whole genome duplication [Source:SGD;Acc:S000005542])

HSP 1 Score: 65.4698 bits (158), Expect = 3.752e-13
Identity = 50/207 (24.15%), Postives = 98/207 (47.34%), Query Frame = 3 
Query:   42 KMYKIFCVLFI--LLHSAFS-----FFISVSPNVEECFFDRIKPDTDMLLL-YEVAEGGSLDIDAKVLDPSGSILYSAVKKSDDKFTFRTKVDGIYKYCFSNTMSSVTNKILMFSLDTISPAKKDSPDSHSKLEEMVS-----ELDKALTTVKHEQEYMETREKIHRKINENTNSRVLLWAIFEACVLIIMSAGQVYYLKRFFEVRR 623
            +++ +  +LF   LL  AFS       IS+    +EC +  +  D D+L++ Y+V  GG+ +ID  +  P GS++ +  +K    F  ++   G Y +C SN   +   K+     +     +K+   SH   E++++     E+D+ L  +    +Y+  RE  +     +T SR+   ++    V++ +S  Q   ++ FF  R+
Sbjct:    2 RVFTLIAILFSSSLLTHAFSSNYAPVGISLPAFTKECLYYDLSSDKDVLVVSYQVLTGGNFEIDFDITAPDGSVIVTERQKKHSDFLLKSFGIGKYTFCLSNNYGTSPKKV-----EITLEKEKEIVSSHESKEDIIANNAIEEIDRNLNKITKTMDYLRAREWRNMYTVSSTESRLTWLSLLIMGVMVGISIVQALIIQFFFTSRQ 203
[Close]
BLAST of Transmembrane emp24 domain-containing protein vs. Ensembl Yeast
Match: ERP5 (Protein with similarity to Emp24p and Erv25p; member of the p24 family involved in ER to Golgi transport [Source:SGD;Acc:S000001152])

HSP 1 Score: 60.077 bits (144), Expect = 2.798e-11
Identity = 48/207 (23.19%), Postives = 98/207 (47.34%), Query Frame = 3 
Query:   60 CVLFILLHSAFSFFISVSPNVEECFFDRIK------PDTDMLL----LYEVAEGGSLDIDA-KVLDPSGSILYSAVKKSDDKFTFRTKVDGIYKYCFSNTMSSVTNKILMF------SLDTISPAKKDSPDSHSKLEEMVSELDKALTTVKHEQEYMETREKIHRKINENTNSRVLLWAIFEACVLIIMSAGQVYYLKRFFEVRRVV 629
            C+LF +  +  +          +CF++ +        D D+ +    L+E     SL I   +  D    +L      + D  TF     G +++CF+   S  +  + +F      +++ +   KK+  +S   L+  V +L + L++++ EQ+ +  +E   R  +E+ NS+++ W++F+  +L+   A Q+ YLK FF  ++VV
Sbjct:   10 CLLFAITQAVGAVHFYAKSGETKCFYEHLSRGNLLIGDLDLYVEKDGLFEEDPESSLTITVDETFDNDHRVLNQKNSHTGD-VTFTALDTGEHRFCFTPFYSKKSATLRVFIELEIGNVEALDSKKKEDMNS---LKGRVGQLTQRLSSIRKEQDAIREKEAEFRNQSESANSKIMTWSVFQLLILLGTCAFQLRYLKNFFVKQKVV 212
[Close]
BLAST of Transmembrane emp24 domain-containing protein vs. Ensembl Yeast
Match: ERP6 (Member of the p24 family involved in ER to Golgi transport; similar to Emp24p and Erv25p; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; ERP6 has a paralog, ERP1, that arose from the whole genome duplication [Source:SGD;Acc:S000002970])

HSP 1 Score: 54.6842 bits (130), Expect = 2.247e-9
Identity = 49/213 (23.00%), Postives = 91/213 (42.72%), Query Frame = 3 
Query:   54 IFCVLFILLHSAFSFFISVSPNVEECFFDRIKPDT------------DMLLLYEVAE----GGSLDIDAKVLDPSGSILYSAVKKSDDKFTFRTKVDGIYKYCFSNTMSSVTNKI-----LMFSLDTISPAKKDSPDSHSKLEEMVSELDKALTTVKHEQEYMETREKIHRKINENTNSRVLLWAIFEACVLIIMSAGQVYYLKRFFEVRRVV 629
            IF    +L     +F+        +CF   +  DT            D L  Y +      G  +D++ +V D +  +++     S D F+F     G YK C  + +++   K      + F +   +       ++   L   VS L+  +  ++ EQ+ M  RE+  R I+E+ NSR + W + +  +LII+   Q+  L+ FF  ++V+
Sbjct:    6 IFLAFVLLPFRVSAFYFYGYGGDRKCFLKELSKDTLLKGSYNLEVYDDKLADYALPSYNDYGIVIDVE-EVFDNNHRVVHQQGSPSGD-FSFLALESGEYKICLQSRVNNWVGKTKTKLEIEFEVGFEAMLDMQRKETLESLHGKVSILNSKIVDIRREQQLMREREESFRDISESVNSRAMWWTVTQVTLLIIICVWQMKSLRSFFVKQKVL 216
[Close]
BLAST of Transmembrane emp24 domain-containing protein vs. Ensembl Yeast
Match: ERP2 (Member of the p24 family involved in ER to Golgi transport; similar to Emp24p and Erv25p; role in misfolded protein quality control; forms a heterotrimeric complex with Erp1p, Emp24p, and Erv25p; localized to COPII-coated vesicles; ERP2 has a paralog, ERP4, that arose from the whole genome duplication [Source:SGD;Acc:S000000005])

HSP 1 Score: 53.9138 bits (128), Expect = 4.431e-9
Identity = 40/156 (25.64%), Postives = 67/156 (42.95%), Query Frame = 3 
Query:  102 ISVSPNVEEC-FFDRIKPDTDMLLLYEVAEGGSLDIDAKVLDPSGSILYSAVKKSDDKFTFRTKVDGIYKYCFSNTMSSVTNKILMFSLDTISPAKKDSPDSHSK--------LEEMVSELDKALTTVKHEQEYMETREKIHRKINENTNSRVLLW 542
            IS+    +EC ++D +  D  + + Y+V  GG+ +ID  +  P GS++ S  +K    F  ++   G Y +CFSN   +   K+     +     +K   D H              V E+D+ L  +     Y+  RE  +     +T SR L W
Sbjct:   34 ISLPAFSKECLYYDMVTEDDSLAVGYQVLTGGNFEIDFDITAPDGSVITSEKQKKYSDFLLKSFGVGKYTFCFSNNYGTALKKV-----EITLEKEKTLTDEHEADVNNDDIIANNAVEEIDRNLNKITKTLNYLRAREWRNMSTVNSTESR-LTW 183
[Close]
BLAST of Transmembrane emp24 domain-containing protein vs. Ensembl Nematostella
Match: EDO31547 (Transmembrane emp24 domain-containing protein [Source:UniProtKB/Swiss-Prot;Acc:A7SXK3])

HSP 1 Score: 221.861 bits (564), Expect = 1.678e-72
Identity = 105/193 (54.40%), Postives = 138/193 (71.50%), Query Frame = 3 
Query:   63 VLFILLHSAFSFFISVSPNVEECFFDRIKPDTDMLLLYEVAEGGSLDIDAKVLDPSGSILYSAVKKSDDKFTFRTKVDGIYKYCFSNTMSSVTNKILMFSLDTISPAKKDSPD----SHSKLEEMVSELDKALTTVKHEQEYMETREKIHRKINENTNSRVLLWAIFEACVLIIMSAGQVYYLKRFFEVRRVV 629
            VL  L  S+  +FI++  + EECF D++   T M L++EVAEGG LDID K++ P   ++YS  +++  K+TF   +DG Y YCFSN MS++T K+L FS+D I  A KD+       H KL EMVS+L +A+T VKHEQEYME RE+IHR IN+NTNSRV+ W+ FE+ VL+ M+ GQVYYLKRFFEVRRVV
Sbjct:   12 VLMFLARSSLCYFITIDAHGEECFHDKVTSGTKMGLIFEVAEGGFLDIDVKIIGPDQKVIYSGERETSGKYTFAAHMDGTYNYCFSNKMSTMTPKVLKFSMD-IGEAPKDTSKEDNAGHDKLSEMVSQLSEAMTGVKHEQEYMEVRERIHRSINDNTNSRVVWWSFFESLVLVAMTLGQVYYLKRFFEVRRVV 203
[Close]
BLAST of Transmembrane emp24 domain-containing protein vs. Ensembl Nematostella
Match: EDO42051 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S2I7])

HSP 1 Score: 98.5969 bits (244), Expect = 8.662e-25
Identity = 60/196 (30.61%), Postives = 98/196 (50.00%), Query Frame = 3 
Query:   66 LFILLHSAFSFFISVSPNVEECFFDRIKPDTDMLLLYEVAEGGSLDIDAKVLDPSGSILYSAVKKSDDKFTFRTKVDGIYKYCFSNTMSSVTNKILMFSLDTISPAK--KDSPDSHSKLEEMVSELDKALTTVKHE--------QEYMETREKIHRKINENTNSRVLLWAIFEACVLIIMSAGQVYYLKRFFEVRR 623
            L  +L S       +  N  +CF++ +K D    L ++V  GG+ D+D  + D +   LYS  KK  D  TF  +  GIYK+CFSN  S++++K + F   +    +  K   + H+ L +M    + A  T+ HE        Q +   RE   R + E  N RV  W++ E+ +++I+   QV+ L++FF  RR
Sbjct:   16 LSCILVSCTELTFELEDNARQCFYEELKKDAKATLEFQVITGGNYDVDVILYDINEKELYSVQKKQYDSHTFTVEQPGIYKFCFSNEFSTISHKTVYFDFQSGEETQLTKTMGNHHTALTQM----ETACVTI-HENLKIAIDYQTHHRLRESQGRDMAEYLNERVQWWSVGESVLIVIVGICQVFILRQFFAERR 206
[Close]
BLAST of Transmembrane emp24 domain-containing protein vs. Ensembl Nematostella
Match: EDO35763 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SKI6])

HSP 1 Score: 84.7297 bits (208), Expect = 1.717e-19
Identity = 60/210 (28.57%), Postives = 101/210 (48.10%), Query Frame = 3 
Query:   48 YKIFCVLFILLHSAF--------SFFISVSPNVEECFFDRIKPDTDMLLLYEVAEGGSLDIDAKVLDPSGSILYSAVKKSDDKFTFRTKVDGIYKYCFSNTMSSVTNKILMFSL-----DTISP--AKKD---SPDSHSK----LEEMVSELDKALTTVKHEQEYMETREKIHRKINENTNSRVLLWAIFEACVLIIMSAGQVYYLKRFF 611
            +   CV F +L   +         F   V P   +CF++ IK +  + + Y+V EGG LDI   +  PSG I      ++D+  +  T+ +G Y++CF NT S+V +K +   L     D I      KD     D H +    LE +  +LDKA    +H Q ++ +      ++ ++ +SRV  W++ ++  LI ++  QV  +K FF
Sbjct:   11 WLTLCVGFFVLQQTWRPSSALKSGFTFRVDPGKRDCFYETIKRNVTLDVEYQVIEGGDLDIGFTLQAPSGKIAIEDGHRTDEAHSLVTEEEGEYEFCFDNTFSTVASKAIFADLGVDFEDDIQKMIGIKDENLEEDLHDRFVRTLENVRVDLDKA----EHIQNFISSAAARDFRLAKSKDSRVFWWSLIQSVALIGVAIVQVNVVKHFF 216
[Close]
BLAST of Transmembrane emp24 domain-containing protein vs. Ensembl Nematostella
Match: EDO49537 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RGJ6])

HSP 1 Score: 75.485 bits (184), Expect = 2.333e-16
Identity = 50/185 (27.03%), Postives = 88/185 (47.57%), Query Frame = 3 
Query:   54 IFCVLFI-LLHSAFSFFISVSPNVEECFFDRIKPDTDMLLLYEVAEGGSLDIDAKVLDPSGSILYSAVKKSDDKFTFRTKVDGIYKYCFSNTMSSVTNKILMF---------SLDTISPAKKDSPDSHS--KLEEMVSELDKALTTVKHEQEYMETREKIHRKINENTNSRVLLWAIFEACVLII 572
            IF V F  L++ +F+  +    +  ECF+  I   T+  L +    G    +D  + DPSG+++Y   KK  D   F T ++G Y+ CFSN       + L++            TI  A +  P S +  +LE  +S + + +  ++  Q Y   RE   R   E+ NS+V  W+I ++ ++++
Sbjct:    9 IFLVAFSSLIYCSFARHLQFHLSGYECFYQDILEKTECSLEFAPITGNDPKVDVTLEDPSGNVIYRVDKKDYDLHKFTTTMNGTYQVCFSNVYDFTIGENLVYFDFIAGVEDEFGTIGTAGETGPASKALTQLETSLSTIHENMNLIERYQNYYRLREANGRIAAESLNSKVQWWSIGQSIIVVL 193
[Close]
BLAST of Transmembrane emp24 domain-containing protein vs. Ensembl Nematostella
Match: EDO35953 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SK51])

HSP 1 Score: 69.707 bits (169), Expect = 3.579e-14
Identity = 52/206 (25.24%), Postives = 94/206 (45.63%), Query Frame = 3 
Query:   75 LLHSAFSFFISVSPNVEECFFDRIKPDTDMLL------LYE------VAEGGSLDIDAKVLDPSGSILYSAVKKSDDKFTFRTKVDGIYKYCF---SNTMSSVTNKILMFSLD-TISPAKKD-----SPDSHSKLEEMVSELDKALTTVKHEQEYMETREKIHRKINENTNSRVLLWAIFEACVLIIMSAGQVYYLKRFFEVRRVV 629
            +L +  + +  +    ++CF + I PD  M++      LY+      +     + +  +V DP+G I+ S    S+ +FTF +   G +  C    S   S      L   LD  +     D     + D  ++L+  + +L   +  +  EQ Y   RE+  R  +E+TN RVL WA+ +  +L+     Q+ +LK FFE +++V
Sbjct:   13 MLGNVQALYFHMGETEKKCFIEEI-PDETMVIGKYKTQLYDENIKDFLPSSPGIGMHVEVKDPNGKIIMSKYYSSEGRFTFTSHTPGEHVICLHSNSTRWSLWAGGRLRIHLDIQVGEHANDYAQIAAKDKLTELQLRIRQLLDQVEQISKEQNYQRFREERFRMTSESTNQRVLWWALAQTVILLATGFWQMRHLKGFFEAKKLV 217
[Close]
BLAST of Transmembrane emp24 domain-containing protein vs. Ensembl Medaka
Match: tmed2 (transmembrane emp24 domain-containing protein 2 [Source:NCBI gene;Acc:101161906])

HSP 1 Score: 221.09 bits (562), Expect = 1.241e-71
Identity = 104/203 (51.23%), Postives = 146/203 (71.92%), Query Frame = 3 
Query:   51 KIFCVLFILLHSAFSFFISVSPNVEECFFDRIKPDTDMLLLYEVAEGGSLDIDAKVLDPSGSILYSAVKKSDDKFTFRTKVDGIYKYCFSNTMSSVTNKILMFSLDTISPAKK---------DSPDSH-SKLEEMVSELDKALTTVKHEQEYMETREKIHRKINENTNSRVLLWAIFEACVLIIMSAGQVYYLKRFFEVRRVV 629
            ++  +L +L  +A  +F+S+  + EECF++R+   T M L++EVAEGG LDID +++ P G  +Y   ++S  K++    +DG YK+CFSN MS++T KI+MF++D I  A K         +S D+H +KLEEM++EL  A+T VKHEQEYME RE+IHR IN+NTNSRV+LW+ FEA VL+ M+ GQ+YYLKRFFEVRRVV
Sbjct:    6 ELVVLLAVLTATASGYFVSIDAHAEECFYERVNSGTKMGLMFEVAEGGFLDIDVEIMGPDGKQIYKGDRESSGKYSVAAHMDGTYKFCFSNKMSTMTPKIVMFTID-IGEAPKGQNMETEGANSWDAHQNKLEEMINELAVAMTAVKHEQEYMEVRERIHRAINDNTNSRVVLWSFFEALVLVAMTLGQIYYLKRFFEVRRVV 207
[Close]
BLAST of Transmembrane emp24 domain-containing protein vs. Ensembl Medaka
Match: tmed2 (transmembrane emp24 domain-containing protein 2 [Source:NCBI gene;Acc:101161906])

HSP 1 Score: 220.705 bits (561), Expect = 1.477e-71
Identity = 99/196 (50.51%), Postives = 142/196 (72.45%), Query Frame = 3 
Query:   51 KIFCVLFILLHSAFSFFISVSPNVEECFFDRIKPDTDMLLLYEVAEGGSLDIDAKVLDPSGSILYSAVKKSDDKFTFRTKVDGIYKYCFSNTMSSVTNKILMFSLDTISPAKKDSPDS---HSKLEEMVSELDKALTTVKHEQEYMETREKIHRKINENTNSRVLLWAIFEACVLIIMSAGQVYYLKRFFEVRRVV 629
            ++  +L +L  +A  +F+S+  + EECF++R+   T M L++EVAEGG LDID +++ P G  +Y   ++S  K++    +DG YK+CFSN MS++T KI+MF++D     K  + ++    +KLEEM++EL  A+T VKHEQEYME RE+IHR IN+NTNSRV+LW+ FEA VL+ M+ GQ+YYLKRFFEVRRVV
Sbjct:    6 ELVVLLAVLTATASGYFVSIDAHAEECFYERVNSGTKMGLMFEVAEGGFLDIDVEIMGPDGKQIYKGDRESSGKYSVAAHMDGTYKFCFSNKMSTMTPKIVMFTIDIGEAPKGQNMETEAHQNKLEEMINELAVAMTAVKHEQEYMEVRERIHRAINDNTNSRVVLWSFFEALVLVAMTLGQIYYLKRFFEVRRVV 201
[Close]
BLAST of Transmembrane emp24 domain-containing protein vs. Ensembl Medaka
Match: tmed2 (transmembrane emp24 domain-containing protein 2 [Source:NCBI gene;Acc:101161906])

HSP 1 Score: 153.295 bits (386), Expect = 1.888e-45
Identity = 74/181 (40.88%), Postives = 114/181 (62.98%), Query Frame = 3 
Query:   51 KIFCVLFILLHSAFSFFISVSPNVEECFFDRIKPDTDMLLLYEVAEGGSLDIDAKVLDPSGSILYSAVKKSDDKFTFRTKVDGIYKYCFSNTMSSVTNKILMFSLDTISPAKKDSPDS---HSKLEEMVSELDKALTTVKHEQEYMETREKIHRKIN--ENTNSRVLLWAIFEACVLIIMS 578
            ++  +L +L  +A  +F+S+  + EECF++R+   T M L++EVAEGG LDID +++ P G  +Y   ++S  K++    +DG YK+CFSN MS++T KI+MF++D     K  + ++    +KLEEM++EL  A+T VKHEQEYME RE+IHR     E   S     +    CVL ++S
Sbjct:    6 ELVVLLAVLTATASGYFVSIDAHAEECFYERVNSGTKMGLMFEVAEGGFLDIDVEIMGPDGKQIYKGDRESSGKYSVAAHMDGTYKFCFSNKMSTMTPKIVMFTIDIGEAPKGQNMETEAHQNKLEEMINELAVAMTAVKHEQEYMEVRERIHRASTCPERRASNAGSASEMNRCVLFLLS 186
[Close]
BLAST of Transmembrane emp24 domain-containing protein vs. Ensembl Medaka
Match: tmed2 (transmembrane emp24 domain-containing protein 2 [Source:NCBI gene;Acc:101161906])

HSP 1 Score: 153.295 bits (386), Expect = 1.888e-45
Identity = 74/181 (40.88%), Postives = 114/181 (62.98%), Query Frame = 3 
Query:   51 KIFCVLFILLHSAFSFFISVSPNVEECFFDRIKPDTDMLLLYEVAEGGSLDIDAKVLDPSGSILYSAVKKSDDKFTFRTKVDGIYKYCFSNTMSSVTNKILMFSLDTISPAKKDSPDS---HSKLEEMVSELDKALTTVKHEQEYMETREKIHRKIN--ENTNSRVLLWAIFEACVLIIMS 578
            ++  +L +L  +A  +F+S+  + EECF++R+   T M L++EVAEGG LDID +++ P G  +Y   ++S  K++    +DG YK+CFSN MS++T KI+MF++D     K  + ++    +KLEEM++EL  A+T VKHEQEYME RE+IHR     E   S     +    CVL ++S
Sbjct:    6 ELVVLLAVLTATASGYFVSIDAHAEECFYERVNSGTKMGLMFEVAEGGFLDIDVEIMGPDGKQIYKGDRESSGKYSVAAHMDGTYKFCFSNKMSTMTPKIVMFTIDIGEAPKGQNMETEAHQNKLEEMINELAVAMTAVKHEQEYMEVRERIHRASTCPERRASNAGSASEMNRCVLFLLS 186
[Close]
BLAST of Transmembrane emp24 domain-containing protein vs. Ensembl Medaka
Match: tmed2 (transmembrane emp24 domain-containing protein 2 [Source:NCBI gene;Acc:101161906])

HSP 1 Score: 153.295 bits (386), Expect = 1.888e-45
Identity = 74/181 (40.88%), Postives = 114/181 (62.98%), Query Frame = 3 
Query:   51 KIFCVLFILLHSAFSFFISVSPNVEECFFDRIKPDTDMLLLYEVAEGGSLDIDAKVLDPSGSILYSAVKKSDDKFTFRTKVDGIYKYCFSNTMSSVTNKILMFSLDTISPAKKDSPDS---HSKLEEMVSELDKALTTVKHEQEYMETREKIHRKIN--ENTNSRVLLWAIFEACVLIIMS 578
            ++  +L +L  +A  +F+S+  + EECF++R+   T M L++EVAEGG LDID +++ P G  +Y   ++S  K++    +DG YK+CFSN MS++T KI+MF++D     K  + ++    +KLEEM++EL  A+T VKHEQEYME RE+IHR     E   S     +    CVL ++S
Sbjct:    6 ELVVLLAVLTATASGYFVSIDAHAEECFYERVNSGTKMGLMFEVAEGGFLDIDVEIMGPDGKQIYKGDRESSGKYSVAAHMDGTYKFCFSNKMSTMTPKIVMFTIDIGEAPKGQNMETEAHQNKLEEMINELAVAMTAVKHEQEYMEVRERIHRASTCPERRASNAGSASEMNRCVLFLLS 186
[Close]
BLAST of Transmembrane emp24 domain-containing protein vs. Planmine SMEST
Match: SMESG000026239.1 (SMESG000026239.1)

HSP 1 Score: 399.823 bits (1026), Expect = 2.130e-142
Identity = 194/195 (99.49%), Postives = 194/195 (99.49%), Query Frame = 3 
Query:   45 MYKIFCVLFILLHSAFSFFISVSPNVEECFFDRIKPDTDMLLLYEVAEGGSLDIDAKVLDPSGSILYSAVKKSDDKFTFRTKVDGIYKYCFSNTMSSVTNKILMFSLDTISPAKKDSPDSHSKLEEMVSELDKALTTVKHEQEYMETREKIHRKINENTNSRVLLWAIFEACVLIIMSAGQVYYLKRFFEVRRVV 629
            MYKIFCVLFILLHSA SFFISVSPNVEECFFDRIKPDTDMLLLYEVAEGGSLDIDAKVLDPSGSILYSAVKKSDDKFTFRTKVDGIYKYCFSNTMSSVTNKILMFSLDTISPAKKDSPDSHSKLEEMVSELDKALTTVKHEQEYMETREKIHRKINENTNSRVLLWAIFEACVLIIMSAGQVYYLKRFFEVRRVV
Sbjct:    1 MYKIFCVLFILLHSALSFFISVSPNVEECFFDRIKPDTDMLLLYEVAEGGSLDIDAKVLDPSGSILYSAVKKSDDKFTFRTKVDGIYKYCFSNTMSSVTNKILMFSLDTISPAKKDSPDSHSKLEEMVSELDKALTTVKHEQEYMETREKIHRKINENTNSRVLLWAIFEACVLIIMSAGQVYYLKRFFEVRRVV 195
[Close]
BLAST of Transmembrane emp24 domain-containing protein vs. Planmine SMEST
Match: SMESG000069470.1 (SMESG000069470.1)

HSP 1 Score: 221.476 bits (563), Expect = 4.675e-72
Identity = 104/196 (53.06%), Postives = 142/196 (72.45%), Query Frame = 3 
Query:   54 IFCVLFILLHSAFSFFISVSPNVEECFFDRIKPDTDMLLLYEVAEGGSLDIDAKVLDPSGSILYSAVKKSDDKFTFRTKVDGIYKYCFSNTMSSVTNKILMFSLDTISPAKKD---SPDSH-SKLEEMVSELDKALTTVKHEQEYMETREKIHRKINENTNSRVLLWAIFEACVLIIMSAGQVYYLKRFFEVRRVV 629
            IF +L  L+     ++I+V  N +ECFFDR+     M+L++EV EGG LDID KV  P G  +Y+  ++S+ K+ F   VDGIYKYCFSN MS++T KI+MFS+D     +++   + D+H +KLE+MV EL  +L  VKH+QEY+E RE++HR INENTNSRV+LW+ FEA +L+ M+ GQVYYL+RFFEVRRVV
Sbjct:    6 IFLILCHLIFKIKGYYITVDANSDECFFDRLVSGAKMMLMFEVVEGGFLDIDVKVFGPDGKAIYTGDRESNGKYAFSAHVDGIYKYCFSNKMSTMTPKIIMFSMDVSQKPRENKEMNTDAHQNKLEDMVYELSNSLLNVKHQQEYLEVRERVHRSINENTNSRVVLWSAFEAVLLLSMTIGQVYYLRRFFEVRRVV 201
[Close]
BLAST of Transmembrane emp24 domain-containing protein vs. Planmine SMEST
Match: SMESG000069470.1 (SMESG000069470.1)

HSP 1 Score: 191.815 bits (486), Expect = 4.653e-61
Identity = 89/157 (56.69%), Postives = 119/157 (75.80%), Query Frame = 3 
Query:  171 LYEVAEGGSLDIDAKVLDPSGSILYSAVKKSDDKFTFRTKVDGIYKYCFSNTMSSVTNKILMFSLDTISPAKKD---SPDSH-SKLEEMVSELDKALTTVKHEQEYMETREKIHRKINENTNSRVLLWAIFEACVLIIMSAGQVYYLKRFFEVRRVV 629
            ++EV EGG LDID KV  P G  +Y+  ++S+ K+ F   VDGIYKYCFSN MS++T KI+MFS+D     +++   + D+H +KLE+MV EL  +L  VKH+QEY+E RE++HR INENTNSRV+LW+ FEA +L+ M+ GQVYYL+RFFEVRRVV
Sbjct:    1 MFEVVEGGFLDIDVKVFGPDGKAIYTGDRESNGKYAFSAHVDGIYKYCFSNKMSTMTPKIIMFSMDVSQKPRENKEMNTDAHQNKLEDMVYELSNSLLNVKHQQEYLEVRERVHRSINENTNSRVVLWSAFEAVLLLSMTIGQVYYLRRFFEVRRVV 157
[Close]
BLAST of Transmembrane emp24 domain-containing protein vs. Planmine SMEST
Match: SMESG000025949.1 (SMESG000025949.1)

HSP 1 Score: 162.155 bits (409), Expect = 6.318e-49
Identity = 73/180 (40.56%), Postives = 116/180 (64.44%), Query Frame = 3 
Query:   84 SAFSFFISVSPNVEECFFDRIKPDTDMLLLYEVAEGGSLDIDAKVLDPSGSILYSAVKKSDDKFTFRTKVDGIYKYCFSNTMSSVTNKILMFSLDTISPAKKDSPDSHSKLEEMVSELDKALTTVKHEQEYMETREKIHRKINENTNSRVLLWAIFEACVLIIMSAGQVYYLKRFFEVRR 623
            SAFS +I + P   ECFFD+   +  ++L++EV EGG +DI+ ++  P   ++Y   ++S+ K+TF T   G Y+YCFSN+M+    KI++F++D I+P K D  +    +  ++SE+   +  VKHE ++++ R ++H +INE TN  +LLW I E   LI +S GQV YL+R+FE RR
Sbjct:   17 SAFSHYIIIEPKETECFFDKANTNDRIVLMFEVIEGGYMDINIQLFGPDKKVIYQGDRESNGKYTFATNQPGKYRYCFSNSMNDKDRKIVLFNMDIITP-KVDQKEPQDSMINLISEMSVRIFDVKHEVQFLKARHQVHYEINEKTNKYILLWVIIEISCLICLSLGQVLYLRRYFEARR 195
[Close]
BLAST of Transmembrane emp24 domain-containing protein vs. Planmine SMEST
Match: SMESG000078201.1 (SMESG000078201.1)

HSP 1 Score: 117.857 bits (294), Expect = 7.269e-32
Identity = 70/202 (34.65%), Postives = 106/202 (52.48%), Query Frame = 3 
Query:   39 SKMYKIFCVLFILLHSAFSFFISVSPNVEECFFDRIKPDTDMLLLYEVAEGGSLDIDAKVLDPSGSILYSAVKKSDDKFTFRTKVDGIYKYCFSNTMSSVTNKILMFSLDTISPAKKDS-----PDSHSKLEEMVSELDKALTTVKHEQEYMETREKIHRKINENTNSRVLLWAIFEACVLIIMSAGQVYYLKRFFEVRRVV 629
            +K++    V  I++++  SF I+++PN EEC FD       +   YEV  GG LDI++K+L P         K S   +    +  G+Y +C  N   S   K + F+L +    + +         +S LEE+V +L   + +VK E EY  TRE+IH + N + N   LLW +FE  +++ MS GQ+ YLK  FEVRR V
Sbjct:    2 NKLHFALFVHIIIINNLSSFEINLNPNSEECLFDYFNKSDKVEFSYEVINGGFLDIESKLLSPMKVEFMRRDKGSYGVYDLVIEQSGLYYFCLINKEGSQVEKTVRFNLFSEPHYRWERNITSRESKNSDLEEIVHDLSFLMHSVKAESEYSLTREQIHDQANRSANRHFLLWGLFEMVLMVAMSIGQIAYLKHLFEVRRFV 203
The following BLAST results are available for this feature:
BLAST of Transmembrane emp24 domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
TMED22.018e-6954.95transmembrane p24 trafficking protein 2 [Source:HG... [more]
TMED22.526e-4662.93transmembrane p24 trafficking protein 2 [Source:HG... [more]
TMED24.082e-4348.65transmembrane p24 trafficking protein 2 [Source:HG... [more]
TMED73.422e-3036.00transmembrane p24 trafficking protein 7 [Source:HG... [more]
TMED39.894e-2832.95transmembrane p24 trafficking protein 3 [Source:HG... [more]
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BLAST of Transmembrane emp24 domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
sel-94.573e-6952.00Suppressor/enhancer of lin-12 protein 9 [Source:U... [more]
F57B10.51.430e-3031.61pep chromosome:WBcel235:I:6562699:6563660:1 gene:W... [more]
Y60A3A.99.307e-1726.07pep chromosome:WBcel235:V:19946691:19949093:-1 gen... [more]
F47G9.14.214e-1025.24pep chromosome:WBcel235:V:11323965:11326964:-1 gen... [more]
K08E4.65.715e-923.90pep chromosome:WBcel235:IV:12077107:12078162:-1 ge... [more]
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BLAST of Transmembrane emp24 domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
CHOp241.150e-6148.15gene:FBgn0029709 transcript:FBtr0343566[more]
CHOp241.150e-6148.15gene:FBgn0029709 transcript:FBtr0070675[more]
CG93082.268e-3332.51gene:FBgn0034681 transcript:FBtr0071749[more]
p24-18.721e-2628.06gene:FBgn0030341 transcript:FBtr0073604[more]
p24-18.721e-2628.06gene:FBgn0030341 transcript:FBtr0334455[more]
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BLAST of Transmembrane emp24 domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
tmed22.650e-7151.96transmembrane p24 trafficking protein 2 [Source:ZF... [more]
tmed29.561e-7152.04transmembrane p24 trafficking protein 2 [Source:ZF... [more]
tmed71.110e-2932.11transmembrane p24 trafficking protein 7 [Source:ZF... [more]
tmed71.110e-2932.11transmembrane p24 trafficking protein 7 [Source:ZF... [more]
tmed71.110e-2932.11transmembrane p24 trafficking protein 7 [Source:ZF... [more]
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BLAST of Transmembrane emp24 domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
tmed21.696e-6853.51transmembrane p24 trafficking protein 2 [Source:NC... [more]
tmed22.503e-6852.60transmembrane p24 trafficking protein 2 [Source:NC... [more]
serinc21.743e-3034.21serine incorporator 2 [Source:Xenbase;Acc:XB-GENE-... [more]
serinc21.920e-3034.86serine incorporator 2 [Source:Xenbase;Acc:XB-GENE-... [more]
tmed55.243e-2229.79transmembrane p24 trafficking protein 5 [Source:NC... [more]
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BLAST of Transmembrane emp24 domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Tmed21.463e-6954.95transmembrane p24 trafficking protein 2 [Source:MG... [more]
Tmed24.201e-5155.63transmembrane p24 trafficking protein 2 [Source:MG... [more]
Tmed21.978e-3961.61transmembrane p24 trafficking protein 2 [Source:MG... [more]
Tmed71.559e-3036.00transmembrane p24 trafficking protein 7 [Source:MG... [more]
Tmed34.078e-2832.95transmembrane p24 trafficking protein 3 [Source:MG... [more]
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BLAST of Transmembrane emp24 domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|A7SXK3|TMED_NEMVE4.093e-7154.40Transmembrane emp24 domain-containing protein OS=N... [more]
sp|P49020|TMED2_CRIGR3.977e-6954.59Transmembrane emp24 domain-containing protein 2 (F... [more]
sp|Q63524|TMED2_RAT9.691e-6954.95Transmembrane emp24 domain-containing protein 2 OS... [more]
sp|Q15363|TMED2_HUMAN9.691e-6954.95Transmembrane emp24 domain-containing protein 2 OS... [more]
sp|Q9R0Q3|TMED2_MOUSE1.023e-6854.95Transmembrane emp24 domain-containing protein 2 OS... [more]
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BLAST of Transmembrane emp24 domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A2I9LNU41.600e-7355.10Cargo transport protein OS=Centruroides hentzi OX=... [more]
A0A1W7RAL91.652e-7354.59Transmembrane emp24 domain-containing protein 2 OS... [more]
A0A0N4VI973.903e-7354.50GOLD domain-containing protein OS=Enterobius vermi... [more]
C3XVK21.554e-7256.41GOLD domain-containing protein OS=Branchiostoma fl... [more]
A0A0N5AML71.752e-7255.15GOLD domain-containing protein OS=Syphacia muris O... [more]
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BLAST of Transmembrane emp24 domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
TMED22.590e-7050.25transmembrane emp24 domain-containing protein 2 [S... [more]
TMED22.590e-7050.25transmembrane emp24 domain-containing protein 2 [S... [more]
TMED21.409e-6948.78transmembrane emp24 domain-containing protein 2 [S... [more]
tmed25.372e-6954.40transmembrane emp24 domain-containing protein 2 [S... [more]
tmed75.110e-2832.40transmembrane p24 trafficking protein 7 [Source:ZF... [more]
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BLAST of Transmembrane emp24 domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
tmed26.555e-5454.93transmembrane p24 trafficking protein 2 [Source:ZF... [more]
tmed39.124e-2432.35transmembrane p24 trafficking protein 3 [Source:ZF... [more]
tmed52.653e-2332.11transmembrane p24 trafficking protein 5 [Source:ZF... [more]
tmed73.252e-2229.44transmembrane p24 trafficking protein 7 [Source:ZF... [more]
tmed51.808e-2027.98transmembrane p24 trafficking protein 5 [Source:ZF... [more]
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BLAST of Transmembrane emp24 domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 5
Match NameE-valueIdentityDescription
EMP246.790e-2229.06Component of the p24 complex; role in misfolded pr... [more]
ERP43.752e-1324.15Member of the p24 family involved in ER to Golgi t... [more]
ERP52.798e-1123.19Protein with similarity to Emp24p and Erv25p; memb... [more]
ERP62.247e-923.00Member of the p24 family involved in ER to Golgi t... [more]
ERP24.431e-925.64Member of the p24 family involved in ER to Golgi t... [more]
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BLAST of Transmembrane emp24 domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO315471.678e-7254.40Transmembrane emp24 domain-containing protein [So... [more]
EDO420518.662e-2530.61Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO357631.717e-1928.57Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO495372.333e-1627.03Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO359533.579e-1425.24Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Transmembrane emp24 domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
tmed21.241e-7151.23transmembrane emp24 domain-containing protein 2 [S... [more]
tmed21.477e-7150.51transmembrane emp24 domain-containing protein 2 [S... [more]
tmed21.888e-4540.88transmembrane emp24 domain-containing protein 2 [S... [more]
tmed21.888e-4540.88transmembrane emp24 domain-containing protein 2 [S... [more]
tmed21.888e-4540.88transmembrane emp24 domain-containing protein 2 [S... [more]
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BLAST of Transmembrane emp24 domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000026239.12.130e-14299.49SMESG000026239.1[more]
SMESG000069470.14.675e-7253.06SMESG000069470.1[more]
SMESG000069470.14.653e-6156.69SMESG000069470.1[more]
SMESG000025949.16.318e-4940.56SMESG000025949.1[more]
SMESG000078201.17.269e-3234.65SMESG000078201.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30008676 ID=SMED30008676|Name=Transmembrane emp24 domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=927bp
TAAATGTACAGCGGCTTTTTGAAGATTTAAAACGTCAGTCAAAAATGTAC
AAGATATTTTGTGTTTTATTTATTCTACTTCACTCAGCTTTTTCCTTTTT
TATAAGTGTATCTCCGAATGTTGAAGAATGTTTTTTCGACAGAATTAAAC
CTGACACTGATATGCTGCTTTTATATGAAGTTGCAGAAGGTGGATCTTTA
GATATAGATGCTAAAGTTTTGGATCCATCAGGGAGTATCCTGTATTCTGC
AGTTAAAAAATCAGATGACAAATTTACATTTCGAACAAAAGTTGATGGAA
TATATAAGTATTGCTTTAGTAATACAATGAGCTCAGTCACTAATAAAATA
TTAATGTTTTCCTTGGATACTATTTCACCAGCTAAAAAAGATTCACCAGA
TTCTCATTCAAAATTAGAAGAAATGGTAAGCGAATTAGATAAAGCTTTAA
CAACTGTTAAACACGAGCAAGAATATATGGAGACCAGGGAAAAAATTCAC
AGAAAAATAAATGAAAATACCAATAGCAGAGTGCTTTTGTGGGCGATTTT
CGAAGCCTGCGTCTTAATAATAATGAGTGCGGGTCAAGTTTATTATCTCA
AGCGGTTTTTTGAGGTTCGTCGCGTGGTATAGAGCAATAGCATTGAAATT
ACGGTTGCTACAATAATCGGCTCGATTTCTATTCAACTAATAGTAGTAAA
TGTATTCAATTTTTTTTGTCAAAATTTGTTTTTATCTACTTCATGTTATT
TATCTCGTTTTTTTAATTGAATTTGATGAAATTTCTTGCTAGAATTAATA
AATTGAAAAATCACGTTGTCAATCGATTAATATTTGGTAACCGGTAATTA
TCAATTATATCTAACAATTTCGGATCACAATCGATTATCGGTGGCCTCGT
TGAGTTTTAGTATCGATTTAATAGATA
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protein sequence of SMED30008676-orf-1

>SMED30008676-orf-1 ID=SMED30008676-orf-1|Name=SMED30008676-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=210bp
NVQRLFEDLKRQSKMYKIFCVLFILLHSAFSFFISVSPNVEECFFDRIKP
DTDMLLLYEVAEGGSLDIDAKVLDPSGSILYSAVKKSDDKFTFRTKVDGI
YKYCFSNTMSSVTNKILMFSLDTISPAKKDSPDSHSKLEEMVSELDKALT
TVKHEQEYMETREKIHRKINENTNSRVLLWAIFEACVLIIMSAGQVYYLK
RFFEVRRVV*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0002032epidermal cell
Vocabulary: INTERPRO
TermDefinition
IPR015720TMP21-related
IPR036598GOLD_dom_sf
IPR009038GOLD_dom
IPR001367Fe_dep_repressor
Vocabulary: biological process
TermDefinition
GO:0006810transport
GO:0015031protein transport
Vocabulary: cellular component
TermDefinition
GO:0016021integral component of membrane
GO:0016020membrane
GO:0030659cytoplasmic vesicle membrane
GO:0031410cytoplasmic vesicle
Vocabulary: molecular function
TermDefinition
GO:0046914transition metal ion binding
GO:0046983protein dimerization activity
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR009038GOLD domainSMARTSM01190EMP24_GP25L_2coord: 31..204
e-value: 1.3E-62
score: 224.0
IPR009038GOLD domainPFAMPF01105EMP24_GP25Lcoord: 32..204
e-value: 5.6E-45
score: 153.5
IPR009038GOLD domainPROSITEPS50866GOLDcoord: 41..123
score: 18.759
NoneNo IPR availablePANTHERPTHR22811:SF31TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN 2coord: 19..204
NoneNo IPR availableTMHMMTMhelixcoord: 15..37
NoneNo IPR availableTMHMMTMhelixcoord: 177..199
IPR015720TMP21-relatedPANTHERPTHR22811TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEINcoord: 19..204
IPR036598GOLD domain superfamilySUPERFAMILYSSF101576Supernatant protein factor (SPF), C-terminal domaincoord: 40..130