Serine/threonine-protein phosphatase 2A regulatory subunit A
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30008675 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 3
Homology
BLAST of Serine/threonine-protein phosphatase 2A regulatory subunit A vs. Ensembl Human
Match: PPP2R1A (protein phosphatase 2 scaffold subunit Aalpha [Source:HGNC Symbol;Acc:HGNC:9302]) HSP 1 Score: 155.221 bits (391), Expect = 2.804e-39 Identity = 151/590 (25.59%), Postives = 277/590 (46.95%), Query Frame = 1
Query: 160 VNIDE-DNIDTAEKLRAFHLLPTVALTLKSENTRTMLIPILETLITTAVDNGDDEALMVIAQKLGDFVPLVGGGNYAGCLLQLLARXXXXXXXXXXXQAACDSLIKIIPTLDSNVVDTNCLQLVRNVFAEDLYCAARKAGVRLIPVCYKIASSESQTELKNRLLHLCMAEDEIPLVRAGAVEQLTDLS-IVAGSVLKPEMIRTLTSLVSDNQRVVRAACVKPLLELGKNVDTNEFDTILFPLLDKLSEDSNRDTRRGVASLISEFQK-IAQKFDKS-LHNLLIKLMEDNEIDARKIVASQLKEFC----AACSHQVLIDFVLPKIREHLNLEREDRVKAELVKSVVTMIPSFKREDSLP-LVQHVLSFLNDSNLQTKQYVFEHFQGLIGLISPSELQLTILPSLFKLFADKNWRIRSGVVASLMLIIPIVDEACCRDTLLPTTLSWLKDPVWNIRQGTCELIGSITGRFPSLLTEKLVKAPIFKELFEDVNYHLRQCWCFLIEAICKSQPKESKSDLLTSFLTNHVNELLLAMISKDQVFNVQISAIRSIKLLSSYLDKNFLHKQXXXXXXXXXXXXXDIDVRDFSDAAL 1902
V IDE N D +L + L T+AL L E TR+ L+P L I +DE L+ +A++LG F LVGG Y CLL L + E +V +A +SL I + ++ + + LV+ + D + +R + L VCY SS + EL+ +LC D+ P+VR A +L + + ++ +K E+I ++L SD Q VR V+ + + + + + + ++ P L + +ED + R VA +E QK + + K+ L LM+D E + R + ++KEFC A C V++ +LP I+E ++ + VK+ L ++ + P +++++ L+ L+ L D + + + + + +I +L ++LP++ +L D WR+R ++ + L+ + + L ++WL D V+ IR+ + + +F + P + D NY R F I + + ++ T H+ +L M + D V NV+ + +S++ + LD + L + V + + + D+DV+ F+ AL
Sbjct: 15 VLIDELRNEDVQLRLNSIKKLSTIALALGVERTRSELLPFLTDTIY-----DEDEVLLALAEQLGTFTTLVGGPEYVHCLLPPLESLATVEETVVRDKAV-ESLRAISHEHSPSDLEAHFVPLVKRLAGGDWF-TSRTSACGLFSVCYPRVSSAVKAELRQYFRNLC--SDDTPMVRRAAASKLGEFAKVLELDNVKSEIIPMFSNLASDEQDSVRLLAVEACVNIAQLLPQEDLEALVMPTLRQAAEDKSWRVRYMVADKFTELQKAVGPEITKTDLVPAFQNLMKDCEAEVRAAASHKVKEFCENLSADCRENVIMSQILPCIKELVS-DANQHVKSALASVIMGLSPILGKDNTIEHLLPLFLAQLKDECPEVRLNIISNLDCVNEVIGIRQLSQSLLPAIVELAEDAKWRVRLAIIEYMPLLAGQLGVEFFDEKLNSLCMAWLVDHVYAIREAATSNLKKLVEKFGKEWAHATI-IPKVLAMSGDPNYLHRMTTLFCINVLSEVCGQD--------ITTKHMLPTVLRM-AGDPVANVRFNVAKSLQKIGPILDNSTLQSE-VKPILEKLTQDQDVDVKYFAQEAL 583
BLAST of Serine/threonine-protein phosphatase 2A regulatory subunit A vs. Ensembl Human
Match: PPP2R1B (protein phosphatase 2 scaffold subunit Abeta [Source:HGNC Symbol;Acc:HGNC:9303]) HSP 1 Score: 153.295 bits (386), Expect = 1.284e-38 Identity = 151/591 (25.55%), Postives = 284/591 (48.05%), Query Frame = 1
Query: 160 VNIDE-DNIDTAEKLRAFHLLPTVALTLKSENTRTMLIPILETLITTAVDNGDDEALMVIAQKLGDFVPLVGGGNYAGCLLQLLARXXXXXXXXXXXQAACDSLIKIIPTLDSNVVDTNCLQLVRNVFAEDLYCAARKAGVRLIPVCYKIASSESQTELKNRLLHLCMAEDEIPLVRAGAVEQLTDLS-IVAGSVLKPEMIRTLTSLVSDNQRVVRAACVKPLLELGKNVDTNEFDTILFPLLDKLSEDSNRDTRRGVASLISEFQKIAQKFDKSLHNLLI---KLMEDNEIDARKIVASQLKEFCAACS----HQVLIDFVLPKIREHLNLEREDRVKAELVKSVVTMIPSFKREDSLP-LVQHVLSFLNDSNLQTKQYVFEHFQGLIGLISPSELQLTILPSLFKLFADKNWRIRSGVVASLMLIIPIVDEACCRDTLLPTTLSWLKDPVWNIRQGTCELIGSITGRFPSLLTEKLVKAPIFKELFEDVNYHLRQCWCFLIEAICKSQPKESKSDLLTSFLTNHVNELLLAMISKDQVFNVQISAIRSIKLLSSYLDKNFLHKQXXXXXXXXXXXXXDIDVRDFSDAAL 1902
V IDE N D +L + L T+AL L E TR+ L+P L I +DE L+ +A++LG+F LVGG ++A CLL L + E +V + A +SL +I ++ + LV+ + + D + +R + L VCY AS+ + E++ + LC D+ P+VR A +L + + ++ +K E++ TSL SD Q VR V+ + + + + ++ +T++ P L + +ED + R VA SE QK A +L++L+ L++D E + R A ++KE ++++ +LP I+E ++ + VK+ L ++ + +E+++ L+ L+ L D + + + + +I +L ++LP++ +L D WR+R ++ + L+ + + L ++WL D V+ IR+ + + +F + + + P + D NY R F I A+ ++ +E T + ++L M + DQV NV+ + +S++ + LD N L + V + + D+DV+ F+ A+
Sbjct: 27 VLIDELRNEDVQLRLNSIKKLSTIALALGVERTRSELLPFLTDTIY-----DEDEVLLALAEQLGNFTGLVGGPDFAHCLLPPLENLATVEETVVRDK-AVESLRQISQEHTPVALEAYFVPLVKRLASGDWF-TSRTSACGLFSVCYPRASNAVKAEIRQQFRSLC--SDDTPMVRRAAASKLGEFAKVLELDSVKSEIVPLFTSLASDEQDSVRLLAVEACVSIAQLLSQDDLETLVMPTLRQAAEDKSWRVRYMVADRFSELQK-AMGPKITLNDLIPAFQNLLKDCEAEVRAAAAHKVKELGENLPIEDRETIIMNQILPYIKELVS-DTNQHVKSALASVIMGLSTILGKENTIEHLLPLFLAQLKDECPDVRLNIISNLDCVNEVIGIRQLSQSLLPAIVELAEDAKWRVRLAIIEYMPLLAGQLGVEFFDEKLNSLCMAWLVDHVYAIREAATNNLMKLVQKFGTEWAQNTI-VPKVLVMANDPNYLHRMTTLFCINALSEACGQE--------ITTKQMLPIVLKM-AGDQVANVRFNVAKSLQKIGPILDTNALQGE-VKPVLQKLGQDEDMDVKYFAQEAI 595
BLAST of Serine/threonine-protein phosphatase 2A regulatory subunit A vs. Ensembl Human
Match: PPP2R1B (protein phosphatase 2 scaffold subunit Abeta [Source:HGNC Symbol;Acc:HGNC:9303]) HSP 1 Score: 153.295 bits (386), Expect = 2.419e-38 Identity = 150/589 (25.47%), Postives = 283/589 (48.05%), Query Frame = 1
Query: 166 IDE-DNIDTAEKLRAFHLLPTVALTLKSENTRTMLIPILETLITTAVDNGDDEALMVIAQKLGDFVPLVGGGNYAGCLLQLLARXXXXXXXXXXXQAACDSLIKIIPTLDSNVVDTNCLQLVRNVFAEDLYCAARKAGVRLIPVCYKIASSESQTELKNRLLHLCMAEDEIPLVRAGAVEQLTDLS-IVAGSVLKPEMIRTLTSLVSDNQRVVRAACVKPLLELGKNVDTNEFDTILFPLLDKLSEDSNRDTRRGVASLISEFQKIAQKFDKSLHNLLI---KLMEDNEIDARKIVASQLKEFCAACS----HQVLIDFVLPKIREHLNLEREDRVKAELVKSVVTMIPSFKREDSLP-LVQHVLSFLNDSNLQTKQYVFEHFQGLIGLISPSELQLTILPSLFKLFADKNWRIRSGVVASLMLIIPIVDEACCRDTLLPTTLSWLKDPVWNIRQGTCELIGSITGRFPSLLTEKLVKAPIFKELFEDVNYHLRQCWCFLIEAICKSQPKESKSDLLTSFLTNHVNELLLAMISKDQVFNVQISAIRSIKLLSSYLDKNFLHKQXXXXXXXXXXXXXDIDVRDFSDAAL 1902
IDE N D +L + L T+AL L E TR+ L+P L I +DE L+ +A++LG+F LVGG ++A CLL L + E +V + A +SL +I ++ + LV+ + + D + +R + L VCY AS+ + E++ + LC D+ P+VR A +L + + ++ +K E++ TSL SD Q VR V+ + + + + ++ +T++ P L + +ED + R VA SE QK A +L++L+ L++D E + R A ++KE ++++ +LP I+E ++ + VK+ L ++ + +E+++ L+ L+ L D + + + + +I +L ++LP++ +L D WR+R ++ + L+ + + L ++WL D V+ IR+ + + +F + + + P + D NY R F I A+ ++ +E T + ++L M + DQV NV+ + +S++ + LD N L + V + + D+DV+ F+ A+
Sbjct: 29 IDELRNEDVQLRLNSIKKLSTIALALGVERTRSELLPFLTDTIY-----DEDEVLLALAEQLGNFTGLVGGPDFAHCLLPPLENLATVEETVVRDK-AVESLRQISQEHTPVALEAYFVPLVKRLASGDWF-TSRTSACGLFSVCYPRASNAVKAEIRQQFRSLC--SDDTPMVRRAAASKLGEFAKVLELDSVKSEIVPLFTSLASDEQDSVRLLAVEACVSIAQLLSQDDLETLVMPTLRQAAEDKSWRVRYMVADRFSELQK-AMGPKITLNDLIPAFQNLLKDCEAEVRAAAAHKVKELGENLPIEDRETIIMNQILPYIKELVS-DTNQHVKSALASVIMGLSTILGKENTIEHLLPLFLAQLKDECPDVRLNIISNLDCVNEVIGIRQLSQSLLPAIVELAEDAKWRVRLAIIEYMPLLAGQLGVEFFDEKLNSLCMAWLVDHVYAIREAATNNLMKLVQKFGTEWAQNTI-VPKVLVMANDPNYLHRMTTLFCINALSEACGQE--------ITTKQMLPIVLKM-AGDQVANVRFNVAKSLQKIGPILDTNALQGE-VKPVLQKLGQDEDMDVKYFAQEAI 595
BLAST of Serine/threonine-protein phosphatase 2A regulatory subunit A vs. Ensembl Human
Match: PPP2R1B (protein phosphatase 2 scaffold subunit Abeta [Source:HGNC Symbol;Acc:HGNC:9303]) HSP 1 Score: 135.961 bits (341), Expect = 4.867e-33 Identity = 151/588 (25.68%), Postives = 273/588 (46.43%), Query Frame = 1
Query: 160 VNIDE-DNIDTAEKLRAFHLLPTVALTLKSENTRTMLIPILETLITTAVDNGDDEALMVIAQKLGDFVPLVGGGNYAGCLLQLLARXXXXXXXXXXXQAACDSLIKIIPTLDSNVVDTNCLQLVRNVFAEDLYCAARKAGVRLIPVCYKIASSESQTELKNRLLHLCMAEDEIPLVRAGAVEQLTDLS-IVAGSVLKPEMIRTLTSLVSDNQRVVRAACVKPLLELGKNVDTNEFDTILFPLLDKLSEDSNRDTRRGVASLISEFQKIAQKFDKSLHNLLI---KLMEDNEIDARKIVASQLKEFCAACSHQVLIDFVLPKIREHLNLEREDRVKAELVKSVVT--MIPSFKREDSLPLVQHVLSFLNDSNLQTKQYVFEHFQGLIGLISPSELQLTILPSLFKLFADKNWRIRSGVVASLMLIIPIVDEACCRDTLLPTTLSWLKDPVWNIRQGTCELIGSITGRFPSLLTEKLVKAPIFKELFEDVNYHLRQCWCFLIEAICKSQPKESKSDLLTSFLTNHVNELLLAMISKDQVFNVQISAIRSIKLLSSYLDKNFLHKQXXXXXXXXXXXXXDIDVRDFSDAAL 1902
V IDE N D +L + L T+AL L E TR+ L+P L I +DE L+ +A++LG+F LVGG ++A CLL L + E +V + A +SL +I ++ + LV+ + + D + +R + L VCY AS+ + E++ + LC D+ P+VR A +L + + ++ +K E++ TSL SD Q VR V+ + + + + ++ +T++ P L + +ED + R VA SE QK A +L++L+ L++D E + R A ++KE NL EDR ++++ ++P K D + +++S L+ N +IG+ +L ++LP++ +L D WR+R ++ + L+ + + L ++WL D V+ IR+ + + +F + + + P + D NY R F I A+ ++ +E T + ++L M + DQV NV+ + +S++ + LD N L + V + + D+DV+ F+ A+
Sbjct: 27 VLIDELRNEDVQLRLNSIKKLSTIALALGVERTRSELLPFLTDTIY-----DEDEVLLALAEQLGNFTGLVGGPDFAHCLLPPLENLATVEETVVRDK-AVESLRQISQEHTPVALEAYFVPLVKRLASGDWF-TSRTSACGLFSVCYPRASNAVKAEIRQQFRSLC--SDDTPMVRRAAASKLGEFAKVLELDSVKSEIVPLFTSLASDEQDSVRLLAVEACVSIAQLLSQDDLETLVMPTLRQAAEDKSWRVRYMVADRFSELQK-AMGPKITLNDLIPAFQNLLKDCEAEVRAAAAHKVKELGE-------------------NLPIEDR------ETIIMNQILPYIKCPD---VRLNIISNLDCVN------------EVIGI---RQLSQSLLPAIVELAEDAKWRVRLAIIEYMPLLAGQLGVEFFDEKLNSLCMAWLVDHVYAIREAATNNLMKLVQKFGTEWAQNTI-VPKVLVMANDPNYLHRMTTLFCINALSEACGQE--------ITTKQMLPIVLKM-AGDQVANVRFNVAKSLQKIGPILDTNALQGE-VKPVLQKLGQDEDMDVKYFAQEAI 550
BLAST of Serine/threonine-protein phosphatase 2A regulatory subunit A vs. Ensembl Human
Match: PPP2R1A (protein phosphatase 2 scaffold subunit Aalpha [Source:HGNC Symbol;Acc:HGNC:9302]) HSP 1 Score: 115.931 bits (289), Expect = 3.293e-27 Identity = 97/337 (28.78%), Postives = 167/337 (49.55%), Query Frame = 1
Query: 196 KLRAFHLLPTVALTLKSENTRTMLIPILETLITTAVDNGDDEALMVIAQKLGDFVPLVGGGNYAGCLLQLLARXXXXXXXXXXXQAACDSLIKIIPTLDSNVVDTNCLQLVRNVFAEDLYCAARKAGVRLIPVCYKIASSESQTELKNRLLHLCMAEDEIPLVRAGAVEQLTDLS-IVAGSVLKPEMIRTLTSLVSDNQRVVRAACVKPLLELGKNVDTNEFDTILFPLLDKLSEDSNRDTRRGVASLISEFQK-IAQKFDKS-LHNLLIKLMEDNEIDARKIVASQLKEFC----AACSHQVLIDFVLPKIREHLNLEREDRVKAELVKSVVTMIP 1185
+L + L T+AL L E TR+ L+P L I +DE L+ +A++LG F LVGG Y CLL L + E +V +A +SL I + ++ + + LV+ + D + +R + L VCY SS + EL+ +LC D+ P+VR A +L + + ++ +K E+I ++L SD Q VR V+ + + + + + + ++ P L + +ED + R VA +E QK + + K+ L LM+D E + R + ++KEFC A C V++ +LP I+E ++ + VK+ L ++ + P
Sbjct: 68 RLNSIKKLSTIALALGVERTRSELLPFLTDTIYD-----EDEVLLALAEQLGTFTTLVGGPEYVHCLLPPLESLATVEETVVRDKAV-ESLRAISHEHSPSDLEAHFVPLVKRLAGGDWF-TSRTSACGLFSVCYPRVSSAVKAELRQYFRNLC--SDDTPMVRRAAASKLGEFAKVLELDNVKSEIIPMFSNLASDEQDSVRLLAVEACVNIAQLLPQEDLEALVMPTLRQAAEDKSWRVRYMVADKFTELQKAVGPEITKTDLVPAFQNLMKDCEAEVRAAASHKVKEFCENLSADCRENVIMSQILPCIKELVS-DANQHVKSALASVIMGLSP 394 HSP 2 Score: 51.6026 bits (122), Expect = 3.799e-6 Identity = 74/361 (20.50%), Postives = 134/361 (37.12%), Query Frame = 1
Query: 580 RLIPVCYKIASSESQTELKNRLLHLCMAEDEIPLVRAGAVEQLTDLSIVAGSVLKPEMIR----TLTSLVSDNQRVVRAACVKPLLELGKNVDTNEFDTILFPLLDKLSEDSNRDTRRGVASLISE-FQKIAQKFDKSLHNLLIKLMEDNEIDARKIVASQLKEFCAACSHQVLIDFVLPKIREHLNLEREDRVKAELVKSVVTMIPSFKREDSLPLVQHVLSFLNDSNLQTKQYVFEHFQGLIGLISPSELQLTILPSLFKLFADKNWRIRSGVVASLMLIIPIVDEACCRDTLLPTTLSWLKDPVWNIRQGTCELIGSITGRFPSLLTEKLVKA---PIFKELFEDVNYHLRQCWCFLI 1638
+L + + +++EL L EDE+ L A EQL + + G PE + L SL + + VVR V+ L + ++ + PL+ +L+ +R L S + +++ L L D+ R+ AS+L EF K+ E D VK+E++ P+ ++ S DS + E + L+ +L+ ++P+L + DK+WR+R V + V + L+P + +KD +R + + E ++ + P KEL D N H++ +I
Sbjct: 74 KLSTIALALGVERTRSELLPFLTDTIYDEDEVLLALA---EQLGTFTTLVGG---PEYVHCLLPPLESLATVEETVVRDKAVESLRAISHEHSPSDLEAHFVPLVKRLAGGDWFTSRTSACGLFSVCYPRVSSAVKAELRQYFRNLCSDDTPMVRRAAASKLGEFA--------------KVLEL------DNVKSEII----------------PMFSNLASDEQDS---VRLLAVEACVNIAQLLPQEDLEALVMPTLRQAAEDKSWRVRYMVADKFTELQKAVGPEITKTDLVPAFQNLMKDCEAEVRAAASHKVKEFCENLSADCRENVIMSQILPCIKELVSDANQHVKSALASVI 389
BLAST of Serine/threonine-protein phosphatase 2A regulatory subunit A vs. Ensembl Celegans
Match: paa-1 (Probable serine/threonine-protein phosphatase PP2A regulatory subunit [Source:UniProtKB/Swiss-Prot;Acc:Q09543]) HSP 1 Score: 154.451 bits (389), Expect = 1.746e-39 Identity = 156/586 (26.62%), Postives = 272/586 (46.42%), Query Frame = 1
Query: 166 IDE-DNIDTAEKLRAFHLLPTVALTLKSENTRTMLIPILETLITTAVDNGDDEALMVIAQKLGDFVPLVGGGNYAGCLLQLLARXXXXXXXXXXXQAACDSLIKIIPTLDSNVVDTNCLQLVRNVFAEDLYCAARKAGVRLIPVCYKIASSESQTELKNRLLHLCMAEDEIPLVRAGAVEQLTDLSIVAGSVLKPEMIRT-LTSLVSDNQRVVRAACVKPLLELGKNVDTNEFDTILFPLLDKLSEDSNRDTRRGVASLISEFQKI-AQKFDKS-LHNLLIKLMEDNEIDARKIVASQLKEFCAAC---SHQVLIDFVLPKIREHLNLEREDRVKAELVKSVVTMIPSFKREDSLP-LVQHVLSFLNDSNLQTKQYVFEHFQGLIGLISPSELQLTILPSLFKLFADKNWRIRSGVVASLMLIIPIVDEACCRDTLLPTTLSWLKDPVWNIRQGTCELIGSITGRFPSLLTEKLVKAPIFKELFEDVNYHLRQCWCFLIEAICKSQPKESKSDLLTSFLTNHVNELLLAMISKDQVFNVQISAIRSIKLLSSYLDKNFLHKQXXXXXXXXXXXXXDIDVRDFSDAA 1899
IDE N D +L + L T+AL L E TR LI L I +DE L+V+A++LG+F PLVGG ++ CLL L + E +V +A +SL KI S ++ + + ++R + D + + R + L V Y S ++ELK+ LC D+ P+VR A +L + + V E + + LT L D Q VR V+ + G +D ++ P+L +L +D + R VA + E Q + + D + L N+ L++D E + R +L+EF Q +I L + + L + VK+EL ++ + P +E ++ L+ + LND + + + + +I ++L ++LP++ L D WR+R +V + L+ + + + LLP L+WL D V++IR+ + ++ +T +F + P ++L +D NY R F + + ++ +E + + + V +D V NV+ +A +S+K + L + L + V L + D DVR FS+ A
Sbjct: 19 IDELRNEDVTLRLNSIRKLSTIALALGVERTRNELIQFLTDTIY-----DEDEVLLVLAEQLGNFTPLVGGPDHVHCLLLPLENLATVEETVVRDKA-VESLRKIADKHSSASLEEHFVPMLRRLATGDWFTS-RTSACGLFSVVYPRVSPAIKSELKSMFRTLC--RDDTPMVRRAAAAKLGEFAKVFEKTAVIEGLHSSLTDLHVDEQDSVRLLTVESAIAFGTLLDKANKKKLIEPILIELFDDKSWRVRYMVAEKLIEIQNVLGEDMDTTHLVNMYTNLLKDPEGEVRCAATQRLQEFALNLPEDKRQNIICNSLLNVAKELVTDGNQLVKSELAGVIMGLAPLIGKEQTVSELLPIYMQLLNDQTPEVRLNIISSLDKVNEVIGAAQLSTSLLPAIVGLAEDGKWRVRLAIVQFMPLLASQLGQEFFDEKLLPLCLNWLTDHVFSIREASTLIMKELTQKFGGQWASTNI-VPKMQKLQKDTNYLQRMTCLFCLNTLSEAMTQEQILKEIMPIVKDLV---------EDDVPNVRFNAAKSLKRIGKNLTPSTLTSE-VKPLLEKLGKDSDFDVRYFSEEA 584
BLAST of Serine/threonine-protein phosphatase 2A regulatory subunit A vs. Ensembl Celegans
Match: paa-1 (Probable serine/threonine-protein phosphatase PP2A regulatory subunit [Source:UniProtKB/Swiss-Prot;Acc:Q09543]) HSP 1 Score: 154.451 bits (389), Expect = 1.746e-39 Identity = 156/586 (26.62%), Postives = 272/586 (46.42%), Query Frame = 1
Query: 166 IDE-DNIDTAEKLRAFHLLPTVALTLKSENTRTMLIPILETLITTAVDNGDDEALMVIAQKLGDFVPLVGGGNYAGCLLQLLARXXXXXXXXXXXQAACDSLIKIIPTLDSNVVDTNCLQLVRNVFAEDLYCAARKAGVRLIPVCYKIASSESQTELKNRLLHLCMAEDEIPLVRAGAVEQLTDLSIVAGSVLKPEMIRT-LTSLVSDNQRVVRAACVKPLLELGKNVDTNEFDTILFPLLDKLSEDSNRDTRRGVASLISEFQKI-AQKFDKS-LHNLLIKLMEDNEIDARKIVASQLKEFCAAC---SHQVLIDFVLPKIREHLNLEREDRVKAELVKSVVTMIPSFKREDSLP-LVQHVLSFLNDSNLQTKQYVFEHFQGLIGLISPSELQLTILPSLFKLFADKNWRIRSGVVASLMLIIPIVDEACCRDTLLPTTLSWLKDPVWNIRQGTCELIGSITGRFPSLLTEKLVKAPIFKELFEDVNYHLRQCWCFLIEAICKSQPKESKSDLLTSFLTNHVNELLLAMISKDQVFNVQISAIRSIKLLSSYLDKNFLHKQXXXXXXXXXXXXXDIDVRDFSDAA 1899
IDE N D +L + L T+AL L E TR LI L I +DE L+V+A++LG+F PLVGG ++ CLL L + E +V +A +SL KI S ++ + + ++R + D + + R + L V Y S ++ELK+ LC D+ P+VR A +L + + V E + + LT L D Q VR V+ + G +D ++ P+L +L +D + R VA + E Q + + D + L N+ L++D E + R +L+EF Q +I L + + L + VK+EL ++ + P +E ++ L+ + LND + + + + +I ++L ++LP++ L D WR+R +V + L+ + + + LLP L+WL D V++IR+ + ++ +T +F + P ++L +D NY R F + + ++ +E + + + V +D V NV+ +A +S+K + L + L + V L + D DVR FS+ A
Sbjct: 19 IDELRNEDVTLRLNSIRKLSTIALALGVERTRNELIQFLTDTIY-----DEDEVLLVLAEQLGNFTPLVGGPDHVHCLLLPLENLATVEETVVRDKA-VESLRKIADKHSSASLEEHFVPMLRRLATGDWFTS-RTSACGLFSVVYPRVSPAIKSELKSMFRTLC--RDDTPMVRRAAAAKLGEFAKVFEKTAVIEGLHSSLTDLHVDEQDSVRLLTVESAIAFGTLLDKANKKKLIEPILIELFDDKSWRVRYMVAEKLIEIQNVLGEDMDTTHLVNMYTNLLKDPEGEVRCAATQRLQEFALNLPEDKRQNIICNSLLNVAKELVTDGNQLVKSELAGVIMGLAPLIGKEQTVSELLPIYMQLLNDQTPEVRLNIISSLDKVNEVIGAAQLSTSLLPAIVGLAEDGKWRVRLAIVQFMPLLASQLGQEFFDEKLLPLCLNWLTDHVFSIREASTLIMKELTQKFGGQWASTNI-VPKMQKLQKDTNYLQRMTCLFCLNTLSEAMTQEQILKEIMPIVKDLV---------EDDVPNVRFNAAKSLKRIGKNLTPSTLTSE-VKPLLEKLGKDSDFDVRYFSEEA 584
BLAST of Serine/threonine-protein phosphatase 2A regulatory subunit A vs. Ensembl Fly
Match: Pp2A-29B (gene:FBgn0260439 transcript:FBtr0100533) HSP 1 Score: 102.064 bits (253), Expect = 3.646e-22 Identity = 112/464 (24.14%), Postives = 209/464 (45.04%), Query Frame = 1
Query: 160 VNIDE-DNIDTAEKLRAFHLLPTVALTLKSENTRTMLIPILETLITTAVDNGDDEALMVIAQKLGDFVPLVGGGNYAGCLLQLLARXXXXXXXXXXXQAACDSLIKIIPTLDSNVVDTNCLQLVRNVFAEDLYCAARKAGVRLIPVCYKIASSESQTELKNRLLHLCMAEDEIPLVRAGAVEQLTDLS-IVAGSVLKPEMIRTLTSLVSDNQRVVRAACVKPLLELGKNVDTNEFDTILFPLLDKLSEDSNRDTRRGVASLISEFQK-IAQKFDK-SLHNLLIKLMEDNEIDARKIVASQLKEFCAACSHQVLIDFVLPKIREHLNLEREDRVKAELVKSVVTMIPSFKREDSLPLVQHVLSFLNDSNLQTKQYVFEHFQGLIGLISPSELQLTILPSLFKLFADKNWRIRSGVVASLMLIIPIVDEACCRDTLLPTTLSWLKDPVWNIRQGTCELIGSITGRF 1539
V IDE N D +L + L T+AL L E TR+ LIP L I +DE L+ +A +LG+F LVGG +A L+ L + E +V +A +SL + + ++ + + ++ + + D + +R + L VCY + + EL+ LC +DE P+VR A +L + + +V LK ++I L D+Q VR V+ + + + + ++ + ++ P L + + DS+ R VA + QK + + + L L++D E + R VA+++K+FCA NL++ ++V+ ++ S+ LP V+ ++S D N K + GL ++ + +LP D+ +R ++++L + ++ +LLP + +D W +R E + ++ G+
Sbjct: 17 VLIDELKNEDVQLRLNSIKKLSTIALALGEERTRSELIPFLTETIY-----DEDEVLLALADQLGNFTSLVGGPEFAMYLIPPLESLATVEETVVRDKAV-ESLRTVAAEHSAQDLEIHVVPTLQRLVSGDWF-TSRTSACGLFSVCYPRVTQPVKAELRANFRKLC--QDETPMVRRAAANKLGEFAKVVETEYLKSDLIPNFVQLAQDDQDSVRLLAVEACVSIAQLLPQDDVEHLVLPTLRQCASDSSWRVRYMVAEKFVDLQKAVGPEITRVDLVPAFQYLLKDAEAEVRAAVATKVKDFCA-------------------NLDKVNQVQI-ILSSI------------LPYVRDLVS---DPNPHVKSALASVIMGLSPMLGAYQTVEQLLPLFLIQLKDECPEVRLNIISNLDCVNDVIGIQQLSQSLLPAIVELAEDSKWRVRLAIIEYMPALAGQL 436
BLAST of Serine/threonine-protein phosphatase 2A regulatory subunit A vs. Ensembl Fly
Match: Pp2A-29B (gene:FBgn0260439 transcript:FBtr0100535) HSP 1 Score: 102.064 bits (253), Expect = 3.646e-22 Identity = 112/464 (24.14%), Postives = 209/464 (45.04%), Query Frame = 1
Query: 160 VNIDE-DNIDTAEKLRAFHLLPTVALTLKSENTRTMLIPILETLITTAVDNGDDEALMVIAQKLGDFVPLVGGGNYAGCLLQLLARXXXXXXXXXXXQAACDSLIKIIPTLDSNVVDTNCLQLVRNVFAEDLYCAARKAGVRLIPVCYKIASSESQTELKNRLLHLCMAEDEIPLVRAGAVEQLTDLS-IVAGSVLKPEMIRTLTSLVSDNQRVVRAACVKPLLELGKNVDTNEFDTILFPLLDKLSEDSNRDTRRGVASLISEFQK-IAQKFDK-SLHNLLIKLMEDNEIDARKIVASQLKEFCAACSHQVLIDFVLPKIREHLNLEREDRVKAELVKSVVTMIPSFKREDSLPLVQHVLSFLNDSNLQTKQYVFEHFQGLIGLISPSELQLTILPSLFKLFADKNWRIRSGVVASLMLIIPIVDEACCRDTLLPTTLSWLKDPVWNIRQGTCELIGSITGRF 1539
V IDE N D +L + L T+AL L E TR+ LIP L I +DE L+ +A +LG+F LVGG +A L+ L + E +V +A +SL + + ++ + + ++ + + D + +R + L VCY + + EL+ LC +DE P+VR A +L + + +V LK ++I L D+Q VR V+ + + + + ++ + ++ P L + + DS+ R VA + QK + + + L L++D E + R VA+++K+FCA NL++ ++V+ ++ S+ LP V+ ++S D N K + GL ++ + +LP D+ +R ++++L + ++ +LLP + +D W +R E + ++ G+
Sbjct: 17 VLIDELKNEDVQLRLNSIKKLSTIALALGEERTRSELIPFLTETIY-----DEDEVLLALADQLGNFTSLVGGPEFAMYLIPPLESLATVEETVVRDKAV-ESLRTVAAEHSAQDLEIHVVPTLQRLVSGDWF-TSRTSACGLFSVCYPRVTQPVKAELRANFRKLC--QDETPMVRRAAANKLGEFAKVVETEYLKSDLIPNFVQLAQDDQDSVRLLAVEACVSIAQLLPQDDVEHLVLPTLRQCASDSSWRVRYMVAEKFVDLQKAVGPEITRVDLVPAFQYLLKDAEAEVRAAVATKVKDFCA-------------------NLDKVNQVQI-ILSSI------------LPYVRDLVS---DPNPHVKSALASVIMGLSPMLGAYQTVEQLLPLFLIQLKDECPEVRLNIISNLDCVNDVIGIQQLSQSLLPAIVELAEDSKWRVRLAIIEYMPALAGQL 436
BLAST of Serine/threonine-protein phosphatase 2A regulatory subunit A vs. Ensembl Fly
Match: Pp2A-29B (gene:FBgn0260439 transcript:FBtr0005088) HSP 1 Score: 102.064 bits (253), Expect = 3.646e-22 Identity = 112/464 (24.14%), Postives = 209/464 (45.04%), Query Frame = 1
Query: 160 VNIDE-DNIDTAEKLRAFHLLPTVALTLKSENTRTMLIPILETLITTAVDNGDDEALMVIAQKLGDFVPLVGGGNYAGCLLQLLARXXXXXXXXXXXQAACDSLIKIIPTLDSNVVDTNCLQLVRNVFAEDLYCAARKAGVRLIPVCYKIASSESQTELKNRLLHLCMAEDEIPLVRAGAVEQLTDLS-IVAGSVLKPEMIRTLTSLVSDNQRVVRAACVKPLLELGKNVDTNEFDTILFPLLDKLSEDSNRDTRRGVASLISEFQK-IAQKFDK-SLHNLLIKLMEDNEIDARKIVASQLKEFCAACSHQVLIDFVLPKIREHLNLEREDRVKAELVKSVVTMIPSFKREDSLPLVQHVLSFLNDSNLQTKQYVFEHFQGLIGLISPSELQLTILPSLFKLFADKNWRIRSGVVASLMLIIPIVDEACCRDTLLPTTLSWLKDPVWNIRQGTCELIGSITGRF 1539
V IDE N D +L + L T+AL L E TR+ LIP L I +DE L+ +A +LG+F LVGG +A L+ L + E +V +A +SL + + ++ + + ++ + + D + +R + L VCY + + EL+ LC +DE P+VR A +L + + +V LK ++I L D+Q VR V+ + + + + ++ + ++ P L + + DS+ R VA + QK + + + L L++D E + R VA+++K+FCA NL++ ++V+ ++ S+ LP V+ ++S D N K + GL ++ + +LP D+ +R ++++L + ++ +LLP + +D W +R E + ++ G+
Sbjct: 17 VLIDELKNEDVQLRLNSIKKLSTIALALGEERTRSELIPFLTETIY-----DEDEVLLALADQLGNFTSLVGGPEFAMYLIPPLESLATVEETVVRDKAV-ESLRTVAAEHSAQDLEIHVVPTLQRLVSGDWF-TSRTSACGLFSVCYPRVTQPVKAELRANFRKLC--QDETPMVRRAAANKLGEFAKVVETEYLKSDLIPNFVQLAQDDQDSVRLLAVEACVSIAQLLPQDDVEHLVLPTLRQCASDSSWRVRYMVAEKFVDLQKAVGPEITRVDLVPAFQYLLKDAEAEVRAAVATKVKDFCA-------------------NLDKVNQVQI-ILSSI------------LPYVRDLVS---DPNPHVKSALASVIMGLSPMLGAYQTVEQLLPLFLIQLKDECPEVRLNIISNLDCVNDVIGIQQLSQSLLPAIVELAEDSKWRVRLAIIEYMPALAGQL 436
BLAST of Serine/threonine-protein phosphatase 2A regulatory subunit A vs. Ensembl Fly
Match: Pp2A-29B (gene:FBgn0260439 transcript:FBtr0339789) HSP 1 Score: 102.064 bits (253), Expect = 4.408e-22 Identity = 112/464 (24.14%), Postives = 209/464 (45.04%), Query Frame = 1
Query: 160 VNIDE-DNIDTAEKLRAFHLLPTVALTLKSENTRTMLIPILETLITTAVDNGDDEALMVIAQKLGDFVPLVGGGNYAGCLLQLLARXXXXXXXXXXXQAACDSLIKIIPTLDSNVVDTNCLQLVRNVFAEDLYCAARKAGVRLIPVCYKIASSESQTELKNRLLHLCMAEDEIPLVRAGAVEQLTDLS-IVAGSVLKPEMIRTLTSLVSDNQRVVRAACVKPLLELGKNVDTNEFDTILFPLLDKLSEDSNRDTRRGVASLISEFQK-IAQKFDK-SLHNLLIKLMEDNEIDARKIVASQLKEFCAACSHQVLIDFVLPKIREHLNLEREDRVKAELVKSVVTMIPSFKREDSLPLVQHVLSFLNDSNLQTKQYVFEHFQGLIGLISPSELQLTILPSLFKLFADKNWRIRSGVVASLMLIIPIVDEACCRDTLLPTTLSWLKDPVWNIRQGTCELIGSITGRF 1539
V IDE N D +L + L T+AL L E TR+ LIP L I +DE L+ +A +LG+F LVGG +A L+ L + E +V +A +SL + + ++ + + ++ + + D + +R + L VCY + + EL+ LC +DE P+VR A +L + + +V LK ++I L D+Q VR V+ + + + + ++ + ++ P L + + DS+ R VA + QK + + + L L++D E + R VA+++K+FCA NL++ ++V+ ++ S+ LP V+ ++S D N K + GL ++ + +LP D+ +R ++++L + ++ +LLP + +D W +R E + ++ G+
Sbjct: 17 VLIDELKNEDVQLRLNSIKKLSTIALALGEERTRSELIPFLTETIY-----DEDEVLLALADQLGNFTSLVGGPEFAMYLIPPLESLATVEETVVRDKAV-ESLRTVAAEHSAQDLEIHVVPTLQRLVSGDWF-TSRTSACGLFSVCYPRVTQPVKAELRANFRKLC--QDETPMVRRAAANKLGEFAKVVETEYLKSDLIPNFVQLAQDDQDSVRLLAVEACVSIAQLLPQDDVEHLVLPTLRQCASDSSWRVRYMVAEKFVDLQKAVGPEITRVDLVPAFQYLLKDAEAEVRAAVATKVKDFCA-------------------NLDKVNQVQI-ILSSI------------LPYVRDLVS---DPNPHVKSALASVIMGLSPMLGAYQTVEQLLPLFLIQLKDECPEVRLNIISNLDCVNDVIGIQQLSQSLLPAIVELAEDSKWRVRLAIIEYMPALAGQL 436
BLAST of Serine/threonine-protein phosphatase 2A regulatory subunit A vs. Ensembl Fly
Match: Pp2A-29B (gene:FBgn0260439 transcript:FBtr0306102) HSP 1 Score: 101.679 bits (252), Expect = 5.537e-22 Identity = 112/464 (24.14%), Postives = 209/464 (45.04%), Query Frame = 1
Query: 160 VNIDE-DNIDTAEKLRAFHLLPTVALTLKSENTRTMLIPILETLITTAVDNGDDEALMVIAQKLGDFVPLVGGGNYAGCLLQLLARXXXXXXXXXXXQAACDSLIKIIPTLDSNVVDTNCLQLVRNVFAEDLYCAARKAGVRLIPVCYKIASSESQTELKNRLLHLCMAEDEIPLVRAGAVEQLTDLS-IVAGSVLKPEMIRTLTSLVSDNQRVVRAACVKPLLELGKNVDTNEFDTILFPLLDKLSEDSNRDTRRGVASLISEFQK-IAQKFDK-SLHNLLIKLMEDNEIDARKIVASQLKEFCAACSHQVLIDFVLPKIREHLNLEREDRVKAELVKSVVTMIPSFKREDSLPLVQHVLSFLNDSNLQTKQYVFEHFQGLIGLISPSELQLTILPSLFKLFADKNWRIRSGVVASLMLIIPIVDEACCRDTLLPTTLSWLKDPVWNIRQGTCELIGSITGRF 1539
V IDE N D +L + L T+AL L E TR+ LIP L I +DE L+ +A +LG+F LVGG +A L+ L + E +V +A +SL + + ++ + + ++ + + D + +R + L VCY + + EL+ LC +DE P+VR A +L + + +V LK ++I L D+Q VR V+ + + + + ++ + ++ P L + + DS+ R VA + QK + + + L L++D E + R VA+++K+FCA NL++ ++V+ ++ S+ LP V+ ++S D N K + GL ++ + +LP D+ +R ++++L + ++ +LLP + +D W +R E + ++ G+
Sbjct: 17 VLIDELKNEDVQLRLNSIKKLSTIALALGEERTRSELIPFLTETIY-----DEDEVLLALADQLGNFTSLVGGPEFAMYLIPPLESLATVEETVVRDKAV-ESLRTVAAEHSAQDLEIHVVPTLQRLVSGDWF-TSRTSACGLFSVCYPRVTQPVKAELRANFRKLC--QDETPMVRRAAANKLGEFAKVVETEYLKSDLIPNFVQLAQDDQDSVRLLAVEACVSIAQLLPQDDVEHLVLPTLRQCASDSSWRVRYMVAEKFVDLQKAVGPEITRVDLVPAFQYLLKDAEAEVRAAVATKVKDFCA-------------------NLDKVNQVQI-ILSSI------------LPYVRDLVS---DPNPHVKSALASVIMGLSPMLGAYQTVEQLLPLFLIQLKDECPEVRLNIISNLDCVNDVIGIQQLSQSLLPAIVELAEDSKWRVRLAIIEYMPALAGQL 436
BLAST of Serine/threonine-protein phosphatase 2A regulatory subunit A vs. Ensembl Zebrafish
Match: ppp2r1ba (protein phosphatase 2, regulatory subunit A, beta a [Source:ZFIN;Acc:ZDB-GENE-040426-2700]) HSP 1 Score: 152.14 bits (383), Expect = 1.563e-38 Identity = 154/591 (26.06%), Postives = 283/591 (47.88%), Query Frame = 1
Query: 160 VNIDE-DNIDTAEKLRAFHLLPTVALTLKSENTRTMLIPILETLITTAVDNGDDEALMVIAQKLGDFVPLVGGGNYAGCLLQLLARXXXXXXXXXXXQAACDSLIKIIPTLDSNVVDTNCLQLVRNVFAEDLYCAARKAGVRLIPVCYKIASSESQTELKNRLLHLCMAEDEIPLVRAGAVEQLTDLS-IVAGSVLKPEMIRTLTSLVSDNQRVVRAACVKPLLELGKNVDTNEFDTILFPLLDKLSEDSNRDTRRGVASLISEFQK-IAQKFDKS-LHNLLIKLMEDNEIDARKIVASQLKEFCAA----CSHQVLIDFVLPKIREHLNLEREDRVKAELVKSVVTMIPSFKREDSLP-LVQHVLSFLNDSNLQTKQYVFEHFQGLIGLISPSELQLTILPSLFKLFADKNWRIRSGVVASLMLIIPIVDEACCRDTLLPTTLSWLKDPVWNIRQ-GTCELIGSITGRFPSLLTEKLVKAPIFKELFEDVNYHLRQCWCFLIEAICKSQPKESKSDLLTSFLTNHVNELLLAMISKDQVFNVQISAIRSIKLLSSYLDKNFLHKQXXXXXXXXXXXXXDIDVRDFSDAAL 1902
V IDE N D +L + L T+AL L E TRT L+P L I +DE L+ +A++LG+F LVGG Y CLL L + E +V +A +SL KI ++ + LV+ + + D + +R + L VCY SS + E++ LC D+ P+VR A +L + + ++ +K ++I T+L SD Q VR V+ + + + + + ++ P L + +ED + R VA S+ QK + + K+ L L++D E + R A+++KEFC +++ +LP ++E ++ + VK+ L ++ + +++++ L+ L+ L D + + + + + +I +L ++LP++ +L D WR+R ++ + L+ + + L ++WL D V+ IR+ TC L+ + +F + + + P + D NY R F I A+ + +E T H+ ++L M S DQV NV+ + +S++ + LD + L + V + + +S D+DV+ F+ A+
Sbjct: 15 VLIDELRNEDVQLRLNSIKKLSTIALALGVERTRTELLPFLTDTIY-----DEDEVLLALAEQLGNFTMLVGGPEYVHCLLPPLESLATVEETVVRDKAV-ESLRKISHEHSPVDLEVHFEPLVKRLASGDWF-TSRTSACGLFSVCYPRVSSTVKAEIRQHFRTLC--SDDTPMVRRAAASKLGEFAKVLELEYVKSDIISLFTALASDEQDSVRLLAVEAGVSIATLLPQEDLEALVMPTLRQAAEDKSWRVRYMVADKFSDLQKAVGPEITKNDLVPAFQNLLKDCEAEVRAAAANKVKEFCENLPEDSRETIIMTHILPCVKELVS-DTNQHVKSALASVIMGLSTILGKDNTIEHLLPLFLAQLKDECPEVRLNIISNLDCVNEVIGIRQLSQSLLPAIVELAEDAKWRVRLAIIEYMPLLAGQLGVEFFDEKLNSLCMAWLVDHVYAIREAATCNLM-KLVEKFGAEWAQNTI-VPKVLGMANDPNYLHRMTTLFCINALSEVCGQE--------ITTKHMLPVVLKM-SNDQVANVRFNVAKSLQKIGPVLDSSCLQTE-VKPVLEKLASDQDMDVKYFAQEAI 583
BLAST of Serine/threonine-protein phosphatase 2A regulatory subunit A vs. Ensembl Zebrafish
Match: ppp2r1bb (protein phosphatase 2, regulatory subunit A, beta b [Source:ZFIN;Acc:ZDB-GENE-040927-20]) HSP 1 Score: 149.828 bits (377), Expect = 1.247e-37 Identity = 153/590 (25.93%), Postives = 281/590 (47.63%), Query Frame = 1
Query: 160 VNIDE-DNIDTAEKLRAFHLLPTVALTLKSENTRTMLIPILETLITTAVDNGDDEALMVIAQKLGDFVPLVGGGNYAGCLLQLLARXXXXXXXXXXXQAACDSLIKIIPTLDSNVVDTNCLQLVRNVFAEDLYCAARKAGVRLIPVCYKIASSESQTELKNRLLHLCMAEDEIPLVRAGAVEQLTDLS-IVAGSVLKPEMIRTLTSLVSDNQRVVRAACVKPLLELGKNVDTNEFDTILFPLLDKLSEDSNRDTRRGVASLISEFQK-IAQKFDKS-LHNLLIKLMEDNEIDARKIVASQLKEFCAA----CSHQVLIDFVLPKIREHLNLEREDRVKAELVKSVVTMIPSFKREDSLPLVQHVLSF----LNDSNLQTKQYVFEHFQGLIGLISPSELQLTILPSLFKLFADKNWRIRSGVVASLMLIIPIVDEACCRDTLLPTTLSWLKDPVWNIRQ-GTCELIGSITGRFPSLLTEKLVKAPIFKELFEDVNYHLRQCWCFLIEAICKSQPKESKSDLLTSFLTNHVNELLLAMISKDQVFNVQISAIRSIKLLSSYLDKNFLHKQXXXXXXXXXXXXXDIDVRDFS 1890
V IDE N D +L + L T+AL L E TRT L+P L I +DE L+ +A++LG F LVGG + CLL L + E +V +A DSL KI ++ + + LV+ + + D + +R + L VCY SS + E++ LC D+ P+VR A +L + + ++ +K ++I T+L SD Q VR V+ + + + + + ++ P L + +ED + R VA SE QK + + K+ L L++D E + R A+++K FC +++ +LP ++E ++ + VK+ L ++ + ++++ V+H+L L D + + + + + +I +L ++LP++ +L D WR+R ++ + L+ + + L ++WL D V+ IR+ TC L+ + +F + + + P + D NY R F I A+ ++ +E T H+ ++L M S DQV NV+ + +S++ + L+ + L + V + + S+ D+DV+ F+
Sbjct: 15 VLIDELRNEDVQLRLNSIKKLSTIALALGVERTRTELLPFLTDTIY-----DEDEVLLALAEQLGSFTVLVGGPEFVHCLLPPLESLATVEETVVRDKAV-DSLRKISQEHSPVDLEVHFVPLVKRLASGDWF-TSRTSACGLFSVCYPRVSSTVKAEIRQHFRTLC--SDDTPMVRRAAASKLGEFAKVLELDYVKSDIIPLFTALASDEQDSVRLLAVEAGVSIATLLPQEDLEALVMPTLRQAAEDKSWRVRYMVADKFSELQKAVGPEITKNDLVPAFQNLLKDCEAEVRAAAANKVKVFCENLPEDSRETIIMTHILPCVKELVS-DTNQHVKSALASVIMGLSTILGKDNT---VEHLLPLFLAQLKDECPEVRLNIISNLDCVNEVIGIRQLSQSLLPAIVELAEDAKWRVRLAIIEYMPLLAGQLGVEFFDEKLNSLCMAWLIDHVYAIREAATCNLM-KLVEKFGAEWAQNTI-VPKVLGMANDSNYLHRMTTLFCINALSEACGQE--------ITTKHMLPVVLKM-STDQVANVRFNVAKSLQKIGPVLESSALQAE-VKPVLEKLSTDQDMDVKYFA 579
BLAST of Serine/threonine-protein phosphatase 2A regulatory subunit A vs. Ensembl Xenopus
Match: ppp2r1b (platelet-derived growth factor beta polypeptide [Source:NCBI gene;Acc:448463]) HSP 1 Score: 161.77 bits (408), Expect = 2.856e-41 Identity = 150/593 (25.30%), Postives = 279/593 (47.05%), Query Frame = 1
Query: 160 VNIDE-DNIDTAEKLRAFHLLPTVALTLKSENTRTMLIPILETLITTAVDNGDDEALMVIAQKLGDFVPLVGGGNYAGCLLQLLARXXXXXXXXXXXQAACDSLIKIIPTLDSNVVDTNCLQLVRNVFAEDLYCAARKAGVRLIPVCYKIASSESQTELKNRLLHLCMAEDEIPLVRAGAVEQLTDLS-IVAGSVLKPEMIRTLTSLVSDNQRVVRAACVKPLLELGKNVDTNEFDTILFPLLDKLSEDSNRDTRRGVASLISEFQK-IAQKFDKS-LHNLLIKLMEDNEIDARKIVASQLKEFC----AACSHQVLIDFVLPKIREHLNLEREDRVKAELVKSVVTMIPSFKREDSLP-LVQHVLSFLNDSNLQTKQYVFEHFQGLIGLISPSELQLTILPSLFKLFADKNWRIRSGVVASLMLIIPIVDEACCRDTLLPTTLSWLKDPVWNIRQGTCELIGSITGRFPSLLTEKLVKAPIFKELFEDVNYHLRQCWCFLIEAICKSQPKESKSDLLTSFLTNHVNELLLAMISKDQVFNVQISAIRSIKLLSSYLDKNFLHKQXXXXXXXXXXXXXDIDVRDFSDAALKGK 1911
V IDE N D +L + L T+AL L E TRT L+P L I +DE L+ +A++LG F LVGG + CLL L + E +V +A +SL KI ++ + + LV+ + + D + +R + L VCY SS + E++ +LC D+ P+VR A +L + + ++ +K ++I T+L SD Q VR V+ + + + + + + ++ P L + +ED + R VA SE QK + + K+ L L++D E + R A ++KEFC A ++++ +LP ++E ++ + VK+ L ++ + +++++ L+ L+ L D + + + + + +I +L ++LP++ +L D WR+R ++ + L+ + + L ++WL D V+ IR+ + + +F + + + P + D NY R F + A+ ++ KE + L+ + ++ DQV NV+ + RS++ + LD L V + D+DV+ F+ A+ GK
Sbjct: 80 VLIDELRNEDVQLRLNSIKKLSTIALALGVERTRTELLPFLTDTIYD-----EDEVLLALAEQLGSFTSLVGGSEFVHCLLPPLESLATVEETVVRDKAV-ESLRKISNEHSPVDLEAHFVPLVKRLASGDWF-TSRTSACGLFSVCYPRVSSTVKAEIRQHFRNLC--SDDTPMVRRAAASKLGEFAKVLELEYVKNDLIPLFTNLASDEQDSVRLLAVEACVSIAQLLPEEDLEALVMPTLRQATEDKSWRVRYMVADKFSELQKAVGPEITKNDLVPAFQNLLKDCEAEVRAAAAHKVKEFCENLPADGRETIIMNHILPYVKELVS-DTNQHVKSALASVIMGLSTILGKDNTIEHLLPLFLAQLKDECPEVRLNIISNLDCVNEVIGIRQLSQSLLPAIVELAEDTKWRVRLAIIEYMPLLAGQLGVEFFDEKLNSLCMAWLVDHVYAIREAATNNLMKLVEKFGAEWAQNTI-VPKVLAMANDPNYLHRMTTLFCVNALSEACGKEITTKLMLPIVLK---------MAADQVANVRFNVARSLQRIGPVLDGTTLQSD-VKPILLKLGQDEDMDVKYFAQEAMTGK 651
BLAST of Serine/threonine-protein phosphatase 2A regulatory subunit A vs. Ensembl Xenopus
Match: ppp2r1b (platelet-derived growth factor beta polypeptide [Source:NCBI gene;Acc:448463]) HSP 1 Score: 159.458 bits (402), Expect = 1.587e-40 Identity = 149/592 (25.17%), Postives = 278/592 (46.96%), Query Frame = 1
Query: 160 VNIDE-DNIDTAEKLRAFHLLPTVALTLKSENTRTMLIPILETLITTAVDNGDDEALMVIAQKLGDFVPLVGGGNYAGCLLQLLARXXXXXXXXXXXQAACDSLIKIIPTLDSNVVDTNCLQLVRNVFAEDLYCAARKAGVRLIPVCYKIASSESQTELKNRLLHLCMAEDEIPLVRAGAVEQLTDLS-IVAGSVLKPEMIRTLTSLVSDNQRVVRAACVKPLLELGKNVDTNEFDTILFPLLDKLSEDSNRDTRRGVASLISEFQK-IAQKFDKS-LHNLLIKLMEDNEIDARKIVASQLKEFC----AACSHQVLIDFVLPKIREHLNLEREDRVKAELVKSVVTMIPSFKREDSLP-LVQHVLSFLNDSNLQTKQYVFEHFQGLIGLISPSELQLTILPSLFKLFADKNWRIRSGVVASLMLIIPIVDEACCRDTLLPTTLSWLKDPVWNIRQGTCELIGSITGRFPSLLTEKLVKAPIFKELFEDVNYHLRQCWCFLIEAICKSQPKESKSDLLTSFLTNHVNELLLAMISKDQVFNVQISAIRSIKLLSSYLDKNFLHKQXXXXXXXXXXXXXDIDVRDFSDAALKG 1908
V IDE N D +L + L T+AL L E TRT L+P L I +DE L+ +A++LG F LVGG + CLL L + E +V +A +SL KI ++ + + LV+ + + D + +R + L VCY SS + E++ +LC D+ P+VR A +L + + ++ +K ++I T+L SD Q VR V+ + + + + + + ++ P L + +ED + R VA SE QK + + K+ L L++D E + R A ++KEFC A ++++ +LP ++E ++ + VK+ L ++ + +++++ L+ L+ L D + + + + + +I +L ++LP++ +L D WR+R ++ + L+ + + L ++WL D V+ IR+ + + +F + + + P + D NY R F + A+ ++ KE + L+ + ++ DQV NV+ + RS++ + LD L V + D+DV+ F+ A+ G
Sbjct: 15 VLIDELRNEDVQLRLNSIKKLSTIALALGVERTRTELLPFLTDTIY-----DEDEVLLALAEQLGSFTSLVGGSEFVHCLLPPLESLATVEETVVRDKAV-ESLRKISNEHSPVDLEAHFVPLVKRLASGDWF-TSRTSACGLFSVCYPRVSSTVKAEIRQHFRNLC--SDDTPMVRRAAASKLGEFAKVLELEYVKNDLIPLFTNLASDEQDSVRLLAVEACVSIAQLLPEEDLEALVMPTLRQATEDKSWRVRYMVADKFSELQKAVGPEITKNDLVPAFQNLLKDCEAEVRAAAAHKVKEFCENLPADGRETIIMNHILPYVKELVS-DTNQHVKSALASVIMGLSTILGKDNTIEHLLPLFLAQLKDECPEVRLNIISNLDCVNEVIGIRQLSQSLLPAIVELAEDTKWRVRLAIIEYMPLLAGQLGVEFFDEKLNSLCMAWLVDHVYAIREAATNNLMKLVEKFGAEWAQNTI-VPKVLAMANDPNYLHRMTTLFCVNALSEACGKEITTKLMLPIVLK---------MAADQVANVRFNVARSLQRIGPVLDGTTLQSD-VKPILLKLGQDEDMDVKYFAQEAMTG 585
BLAST of Serine/threonine-protein phosphatase 2A regulatory subunit A vs. Ensembl Xenopus
Match: ppp2r1b (platelet-derived growth factor beta polypeptide [Source:NCBI gene;Acc:448463]) HSP 1 Score: 156.762 bits (395), Expect = 7.053e-40 Identity = 148/590 (25.08%), Postives = 277/590 (46.95%), Query Frame = 1
Query: 160 VNIDE-DNIDTAEKLRAFHLLPTVALTLKSENTRTMLIPILETLITTAVDNGDDEALMVIAQKLGDFVPLVGGGNYAGCLLQLLARXXXXXXXXXXXQAACDSLIKIIPTLDSNVVDTNCLQLVRNVFAEDLYCAARKAGVRLIPVCYKIASSESQTELKNRLLHLCMAEDEIPLVRAGAVEQLTDLS-IVAGSVLKPEMIRTLTSLVSDNQRVVRAACVKPLLELGKNVDTNEFDTILFPLLDKLSEDSNRDTRRGVASLISEFQK-IAQKFDKS-LHNLLIKLMEDNEIDARKIVASQLKEFC----AACSHQVLIDFVLPKIREHLNLEREDRVKAELVKSVVTMIPSFKREDSLP-LVQHVLSFLNDSNLQTKQYVFEHFQGLIGLISPSELQLTILPSLFKLFADKNWRIRSGVVASLMLIIPIVDEACCRDTLLPTTLSWLKDPVWNIRQGTCELIGSITGRFPSLLTEKLVKAPIFKELFEDVNYHLRQCWCFLIEAICKSQPKESKSDLLTSFLTNHVNELLLAMISKDQVFNVQISAIRSIKLLSSYLDKNFLHKQXXXXXXXXXXXXXDIDVRDFSDAAL 1902
V IDE N D +L + L T+AL L E TRT L+P L I +DE L+ +A++LG F LVGG + CLL L + E +V +A +SL KI ++ + + LV+ + + D + +R + L VCY SS + E++ +LC D+ P+VR A +L + + ++ +K ++I T+L SD Q VR V+ + + + + + + ++ P L + +ED + R VA SE QK + + K+ L L++D E + R A ++KEFC A ++++ +LP ++E ++ + VK+ L ++ + +++++ L+ L+ L D + + + + + +I +L ++LP++ +L D WR+R ++ + L+ + + L ++WL D V+ IR+ + + +F + + + P + D NY R F + A+ ++ KE + L+ + ++ DQV NV+ + RS++ + LD L V + D+DV+ F+ A+
Sbjct: 15 VLIDELRNEDVQLRLNSIKKLSTIALALGVERTRTELLPFLTDTIY-----DEDEVLLALAEQLGSFTSLVGGSEFVHCLLPPLESLATVEETVVRDKAV-ESLRKISNEHSPVDLEAHFVPLVKRLASGDWF-TSRTSACGLFSVCYPRVSSTVKAEIRQHFRNLC--SDDTPMVRRAAASKLGEFAKVLELEYVKNDLIPLFTNLASDEQDSVRLLAVEACVSIAQLLPEEDLEALVMPTLRQATEDKSWRVRYMVADKFSELQKAVGPEITKNDLVPAFQNLLKDCEAEVRAAAAHKVKEFCENLPADGRETIIMNHILPYVKELVS-DTNQHVKSALASVIMGLSTILGKDNTIEHLLPLFLAQLKDECPEVRLNIISNLDCVNEVIGIRQLSQSLLPAIVELAEDTKWRVRLAIIEYMPLLAGQLGVEFFDEKLNSLCMAWLVDHVYAIREAATNNLMKLVEKFGAEWAQNTI-VPKVLAMANDPNYLHRMTTLFCVNALSEACGKEITTKLMLPIVLK---------MAADQVANVRFNVARSLQRIGPVLDGTTLQSD-VKPILLKLGQDEDMDVKYFAQEAM 583
BLAST of Serine/threonine-protein phosphatase 2A regulatory subunit A vs. Ensembl Xenopus
Match: ppp2r1b (platelet-derived growth factor beta polypeptide [Source:NCBI gene;Acc:448463]) HSP 1 Score: 156.377 bits (394), Expect = 1.015e-39 Identity = 147/590 (24.92%), Postives = 276/590 (46.78%), Query Frame = 1
Query: 166 IDE-DNIDTAEKLRAFHLLPTVALTLKSENTRTMLIPILETLITTAVDNGDDEALMVIAQKLGDFVPLVGGGNYAGCLLQLLARXXXXXXXXXXXQAACDSLIKIIPTLDSNVVDTNCLQLVRNVFAEDLYCAARKAGVRLIPVCYKIASSESQTELKNRLLHLCMAEDEIPLVRAGAVEQLTDLS-IVAGSVLKPEMIRTLTSLVSDNQRVVRAACVKPLLELGKNVDTNEFDTILFPLLDKLSEDSNRDTRRGVASLISEFQK-IAQKFDKS-LHNLLIKLMEDNEIDARKIVASQLKEFC----AACSHQVLIDFVLPKIREHLNLEREDRVKAELVKSVVTMIPSFKREDSLP-LVQHVLSFLNDSNLQTKQYVFEHFQGLIGLISPSELQLTILPSLFKLFADKNWRIRSGVVASLMLIIPIVDEACCRDTLLPTTLSWLKDPVWNIRQGTCELIGSITGRFPSLLTEKLVKAPIFKELFEDVNYHLRQCWCFLIEAICKSQPKESKSDLLTSFLTNHVNELLLAMISKDQVFNVQISAIRSIKLLSSYLDKNFLHKQXXXXXXXXXXXXXDIDVRDFSDAALKG 1908
IDE N D +L + L T+AL L E TRT L+P L I +DE L+ +A++LG F LVGG + CLL L + E +V +A +SL KI ++ + + LV+ + + D + +R + L VCY SS + E++ +LC D+ P+VR A +L + + ++ +K ++I T+L SD Q VR V+ + + + + + + ++ P L + +ED + R VA SE QK + + K+ L L++D E + R A ++KEFC A ++++ +LP ++E ++ + VK+ L ++ + +++++ L+ L+ L D + + + + + +I +L ++LP++ +L D WR+R ++ + L+ + + L ++WL D V+ IR+ + + +F + + + P + D NY R F + A+ ++ KE + L+ + ++ DQV NV+ + RS++ + LD L V + D+DV+ F+ A+
Sbjct: 24 IDELRNEDVQLRLNSIKKLSTIALALGVERTRTELLPFLTDTIY-----DEDEVLLALAEQLGSFTSLVGGSEFVHCLLPPLESLATVEETVVRDKAV-ESLRKISNEHSPVDLEAHFVPLVKRLASGDWF-TSRTSACGLFSVCYPRVSSTVKAEIRQHFRNLC--SDDTPMVRRAAASKLGEFAKVLELEYVKNDLIPLFTNLASDEQDSVRLLAVEACVSIAQLLPEEDLEALVMPTLRQATEDKSWRVRYMVADKFSELQKAVGPEITKNDLVPAFQNLLKDCEAEVRAAAAHKVKEFCENLPADGRETIIMNHILPYVKELVS-DTNQHVKSALASVIMGLSTILGKDNTIEHLLPLFLAQLKDECPEVRLNIISNLDCVNEVIGIRQLSQSLLPAIVELAEDTKWRVRLAIIEYMPLLAGQLGVEFFDEKLNSLCMAWLVDHVYAIREAATNNLMKLVEKFGAEWAQNTI-VPKVLAMANDPNYLHRMTTLFCVNALSEACGKEITTKLMLPIVLK---------MAADQVANVRFNVARSLQRIGPVLDGTTLQSD-VKPILLKLGQDEDMDVKYFAQEAMTA 592
BLAST of Serine/threonine-protein phosphatase 2A regulatory subunit A vs. Ensembl Xenopus
Match: ppp2r1b (platelet-derived growth factor beta polypeptide [Source:NCBI gene;Acc:448463]) HSP 1 Score: 156.762 bits (395), Expect = 1.218e-39 Identity = 147/588 (25.00%), Postives = 276/588 (46.94%), Query Frame = 1
Query: 166 IDE-DNIDTAEKLRAFHLLPTVALTLKSENTRTMLIPILETLITTAVDNGDDEALMVIAQKLGDFVPLVGGGNYAGCLLQLLARXXXXXXXXXXXQAACDSLIKIIPTLDSNVVDTNCLQLVRNVFAEDLYCAARKAGVRLIPVCYKIASSESQTELKNRLLHLCMAEDEIPLVRAGAVEQLTDLS-IVAGSVLKPEMIRTLTSLVSDNQRVVRAACVKPLLELGKNVDTNEFDTILFPLLDKLSEDSNRDTRRGVASLISEFQK-IAQKFDKS-LHNLLIKLMEDNEIDARKIVASQLKEFC----AACSHQVLIDFVLPKIREHLNLEREDRVKAELVKSVVTMIPSFKREDSLP-LVQHVLSFLNDSNLQTKQYVFEHFQGLIGLISPSELQLTILPSLFKLFADKNWRIRSGVVASLMLIIPIVDEACCRDTLLPTTLSWLKDPVWNIRQGTCELIGSITGRFPSLLTEKLVKAPIFKELFEDVNYHLRQCWCFLIEAICKSQPKESKSDLLTSFLTNHVNELLLAMISKDQVFNVQISAIRSIKLLSSYLDKNFLHKQXXXXXXXXXXXXXDIDVRDFSDAAL 1902
IDE N D +L + L T+AL L E TRT L+P L I +DE L+ +A++LG F LVGG + CLL L + E +V +A +SL KI ++ + + LV+ + + D + +R + L VCY SS + E++ +LC D+ P+VR A +L + + ++ +K ++I T+L SD Q VR V+ + + + + + + ++ P L + +ED + R VA SE QK + + K+ L L++D E + R A ++KEFC A ++++ +LP ++E ++ + VK+ L ++ + +++++ L+ L+ L D + + + + + +I +L ++LP++ +L D WR+R ++ + L+ + + L ++WL D V+ IR+ + + +F + + + P + D NY R F + A+ ++ KE + L+ + ++ DQV NV+ + RS++ + LD L V + D+DV+ F+ A+
Sbjct: 22 IDELRNEDVQLRLNSIKKLSTIALALGVERTRTELLPFLTDTIY-----DEDEVLLALAEQLGSFTSLVGGSEFVHCLLPPLESLATVEETVVRDKAV-ESLRKISNEHSPVDLEAHFVPLVKRLASGDWF-TSRTSACGLFSVCYPRVSSTVKAEIRQHFRNLC--SDDTPMVRRAAASKLGEFAKVLELEYVKNDLIPLFTNLASDEQDSVRLLAVEACVSIAQLLPEEDLEALVMPTLRQATEDKSWRVRYMVADKFSELQKAVGPEITKNDLVPAFQNLLKDCEAEVRAAAAHKVKEFCENLPADGRETIIMNHILPYVKELVS-DTNQHVKSALASVIMGLSTILGKDNTIEHLLPLFLAQLKDECPEVRLNIISNLDCVNEVIGIRQLSQSLLPAIVELAEDTKWRVRLAIIEYMPLLAGQLGVEFFDEKLNSLCMAWLVDHVYAIREAATNNLMKLVEKFGAEWAQNTI-VPKVLAMANDPNYLHRMTTLFCVNALSEACGKEITTKLMLPIVLK---------MAADQVANVRFNVARSLQRIGPVLDGTTLQSD-VKPILLKLGQDEDMDVKYFAQEAM 588
BLAST of Serine/threonine-protein phosphatase 2A regulatory subunit A vs. Ensembl Mouse
Match: Ppp2r1b (protein phosphatase 2, regulatory subunit A, beta [Source:MGI Symbol;Acc:MGI:1920949]) HSP 1 Score: 158.688 bits (400), Expect = 1.292e-40 Identity = 153/590 (25.93%), Postives = 281/590 (47.63%), Query Frame = 1
Query: 160 VNIDE-DNIDTAEKLRAFHLLPTVALTLKSENTRTMLIPILETLITTAVDNGDDEALMVIAQKLGDFVPLVGGGNYAGCLLQLLARXXXXXXXXXXXQAACDSLIKIIPTLDSNVVDTNCLQLVRNVFAEDLYCAARKAGVRLIPVCYKIASSESQTELKNRLLHLCMAEDEIPLVRAGAVEQLTDLS-IVAGSVLKPEMIRTLTSLVSDNQRVVRAACVKPLLELGKNVDTNEFDTILFPLLDKLSEDSNRDTRRGVASLISEFQK-IAQKFDKS-LHNLLIKLMEDNEIDARKIVASQLKEFC----AACSHQVLIDFVLPKIREHLNLEREDRVKAELVKSVVTMIPSFKREDSLP-LVQHVLSFLNDSNLQTKQYVFEHFQGLIGLISPSELQLTILPSLFKLFADKNWRIRSGVVASLMLIIPIVDEACCRDTLLPTTLSWLKDPVWNIRQGTCELIGSITGRFPSLLTEKLVKAPIFKELFEDVNYHLRQCWCFLIEAICKSQPKESKSDLLTSFLTNHVNELLLAMISKDQVFNVQISAIRSIKLLSSYLDKNFLHKQXXXXXXXXXXXXXDIDVRDFSDAAL 1902
V IDE N D +L + L T+AL L E TRT L+P L I +DE L+ +A++LG+F LVGG ++A CLL L + E +V +A +SL +I ++ + + LV+ + + D + +R + L VCY AS+ + E++ LC D+ P+VR A +L + + ++ +K E++ T+L SD Q VR V+ + + + + + + ++ P L + +ED + R VA SE QK + K S L L+ D E + R A +++E C A V+++ +LP I+E ++ + VK+ L ++ + +E+++ L+ L+ L D + + + + + +I +L ++LP++ +L D WR+R ++ + L+ + + L ++WL D V+ IR+ + + +F + + + P + D NY R F I A+ ++ KE T + ++L M + DQV NV+ + +S++ + LD N L + V + + D+DV+ F+ A+
Sbjct: 27 VLIDELRNEDVQLRLNSIKKLSTIALALGVERTRTELLPFLTDTIY-----DEDEVLLALAEQLGNFTGLVGGPDFAHCLLPPLESLATVEETVVRDKAV-ESLRQISQEHTPVALEAHFVPLVKRLASGDWF-TSRTSACGLFSVCYPRASNAVKAEIRQHFRSLC--SDDTPMVRRAAASKLGEFAKVLELDSVKTEIVPLFTNLASDEQDSVRLLAVEACVSIAQLLSQEDLEALVMPTLRQAAEDKSWRVRYMVADKFSELQKAVGPKIALSDLIPAFQSLLRDCEAEVRAAAAHKVRELCENLPAEGRETVIMNQILPYIKELVS-DTNQHVKSALASVIMGLSTVLGKENTIEHLLPLFLAQLKDECPEVRLNIISNLDCVNEVIGIRQLSQSLLPAIVELAEDAKWRVRLAIIEYMPLLAGQLGVEFFDEKLNSLCMAWLVDHVYAIREAATNNLMKLVQKFGTEWAQNTI-VPKVLVMANDPNYLHRMTTLFCINALSEACGKE--------ITTKQMLPIVLKM-AGDQVANVRFNVAKSLQKIGPILDTNALQGE-VKPVLQKLGQDEDMDVKYFAQEAI 595
BLAST of Serine/threonine-protein phosphatase 2A regulatory subunit A vs. Ensembl Mouse
Match: Ppp2r1b (protein phosphatase 2, regulatory subunit A, beta [Source:MGI Symbol;Acc:MGI:1920949]) HSP 1 Score: 158.303 bits (399), Expect = 3.451e-40 Identity = 153/593 (25.80%), Postives = 281/593 (47.39%), Query Frame = 1
Query: 160 VNIDE-DNIDTAEKLRAFHLLPTVALTLKSENTRTMLIPILETLITTAVDNGDDEALMVIAQKLGDFVPLVGGGNYAGCLLQLLARXXXXXXXXXXXQAACDSLIKIIPTLDSNVVDTNCLQLVRNVFAEDLYCAARKAGVRLIPVCYKIASSESQTELKNRLLHLCMAEDEIPLVRAGAVEQLTDLS-IVAGSVLKPEMIRTLTSLVSDNQRVVRAACVKPLLELGKNVDTNEFDTILFPLLDKLSEDSNRDTRRGVASLISEFQK-IAQKFDKS-LHNLLIKLMEDNEIDARKIVASQLKEFC----AACSHQVLIDFVLPKIREHLNLEREDRVKAELVKSVVTMIPSFKREDSLPLVQHVLSF----LNDSNLQTKQYVFEHFQGLIGLISPSELQLTILPSLFKLFADKNWRIRSGVVASLMLIIPIVDEACCRDTLLPTTLSWLKDPVWNIRQGTCELIGSITGRFPSLLTEKLVKAPIFKELFEDVNYHLRQCWCFLIEAICKSQPKESKSDLLTSFLTNHVNELLLAMISKDQVFNVQISAIRSIKLLSSYLDKNFLHKQXXXXXXXXXXXXXDIDVRDFSDAAL 1902
V IDE N D +L + L T+AL L E TRT L+P L I +DE L+ +A++LG+F LVGG ++A CLL L + E +V + A +SL +I ++ + + LV+ + + D + +R + L VCY AS+ + E++ LC D+ P+VR A +L + + ++ +K E++ T+L SD Q VR V+ + + + + + + ++ P L + +ED + R VA SE QK + K S L L+ D E + R A +++E C A V+++ +LP I+E ++ + VK+ L ++ + +E++ ++H+L L D + + + + + +I +L ++LP++ +L D WR+R ++ + L+ + + L ++WL D V+ IR+ + + +F + + + P + D NY R F I A+ ++ KE T + ++L M + DQV NV+ + +S++ + LD N L + V + + D+DV+ F+ A+
Sbjct: 27 VLIDELRNEDVQLRLNSIKKLSTIALALGVERTRTELLPFLTDTIY-----DEDEVLLALAEQLGNFTGLVGGPDFAHCLLPPLESLATVEETVVRDK-AVESLRQISQEHTPVALEAHFVPLVKRLASGDWF-TSRTSACGLFSVCYPRASNAVKAEIRQHFRSLC--SDDTPMVRRAAASKLGEFAKVLELDSVKTEIVPLFTNLASDEQDSVRLLAVEACVSIAQLLSQEDLEALVMPTLRQAAEDKSWRVRYMVADKFSELQKAVGPKIALSDLIPAFQSLLRDCEAEVRAAAAHKVRELCENLPAEGRETVIMNQILPYIKELVS-DTNQHVKSALASVIMGLSTVLGKENT---IEHLLPLFLAQLKDECPEVRLNIISNLDCVNEVIGIRQLSQSLLPAIVELAEDAKWRVRLAIIEYMPLLAGQLGVEFFDEKLNSLCMAWLVDHVYAIREAATNNLMKLVQKFGTEWAQNTI-VPKVLVMANDPNYLHRMTTLFCINALSEACGKE--------ITTKQMLPIVLKM-AGDQVANVRFNVAKSLQKIGPILDTNALQGE-VKPVLQKLGQDEDMDVKYFAQEAI 595
BLAST of Serine/threonine-protein phosphatase 2A regulatory subunit A vs. Ensembl Mouse
Match: Ppp2r1b (protein phosphatase 2, regulatory subunit A, beta [Source:MGI Symbol;Acc:MGI:1920949]) HSP 1 Score: 157.918 bits (398), Expect = 4.374e-40 Identity = 153/590 (25.93%), Postives = 281/590 (47.63%), Query Frame = 1
Query: 160 VNIDE-DNIDTAEKLRAFHLLPTVALTLKSENTRTMLIPILETLITTAVDNGDDEALMVIAQKLGDFVPLVGGGNYAGCLLQLLARXXXXXXXXXXXQAACDSLIKIIPTLDSNVVDTNCLQLVRNVFAEDLYCAARKAGVRLIPVCYKIASSESQTELKNRLLHLCMAEDEIPLVRAGAVEQLTDLS-IVAGSVLKPEMIRTLTSLVSDNQRVVRAACVKPLLELGKNVDTNEFDTILFPLLDKLSEDSNRDTRRGVASLISEFQK-IAQKFDKS-LHNLLIKLMEDNEIDARKIVASQLKEFC----AACSHQVLIDFVLPKIREHLNLEREDRVKAELVKSVVTMIPSFKREDSLP-LVQHVLSFLNDSNLQTKQYVFEHFQGLIGLISPSELQLTILPSLFKLFADKNWRIRSGVVASLMLIIPIVDEACCRDTLLPTTLSWLKDPVWNIRQGTCELIGSITGRFPSLLTEKLVKAPIFKELFEDVNYHLRQCWCFLIEAICKSQPKESKSDLLTSFLTNHVNELLLAMISKDQVFNVQISAIRSIKLLSSYLDKNFLHKQXXXXXXXXXXXXXDIDVRDFSDAAL 1902
V IDE N D +L + L T+AL L E TRT L+P L I +DE L+ +A++LG+F LVGG ++A CLL L + E +V + A +SL +I ++ + + LV+ + + D + +R + L VCY AS+ + E++ LC D+ P+VR A +L + + ++ +K E++ T+L SD Q VR V+ + + + + + + ++ P L + +ED + R VA SE QK + K S L L+ D E + R A +++E C A V+++ +LP I+E ++ + VK+ L ++ + +E+++ L+ L+ L D + + + + + +I +L ++LP++ +L D WR+R ++ + L+ + + L ++WL D V+ IR+ + + +F + + + P + D NY R F I A+ ++ KE T + ++L M + DQV NV+ + +S++ + LD N L + V + + D+DV+ F+ A+
Sbjct: 27 VLIDELRNEDVQLRLNSIKKLSTIALALGVERTRTELLPFLTDTIY-----DEDEVLLALAEQLGNFTGLVGGPDFAHCLLPPLESLATVEETVVRDK-AVESLRQISQEHTPVALEAHFVPLVKRLASGDWF-TSRTSACGLFSVCYPRASNAVKAEIRQHFRSLC--SDDTPMVRRAAASKLGEFAKVLELDSVKTEIVPLFTNLASDEQDSVRLLAVEACVSIAQLLSQEDLEALVMPTLRQAAEDKSWRVRYMVADKFSELQKAVGPKIALSDLIPAFQSLLRDCEAEVRAAAAHKVRELCENLPAEGRETVIMNQILPYIKELVS-DTNQHVKSALASVIMGLSTVLGKENTIEHLLPLFLAQLKDECPEVRLNIISNLDCVNEVIGIRQLSQSLLPAIVELAEDAKWRVRLAIIEYMPLLAGQLGVEFFDEKLNSLCMAWLVDHVYAIREAATNNLMKLVQKFGTEWAQNTI-VPKVLVMANDPNYLHRMTTLFCINALSEACGKE--------ITTKQMLPIVLKM-AGDQVANVRFNVAKSLQKIGPILDTNALQGE-VKPVLQKLGQDEDMDVKYFAQEAI 595
BLAST of Serine/threonine-protein phosphatase 2A regulatory subunit A vs. Ensembl Mouse
Match: Ppp2r1b (protein phosphatase 2, regulatory subunit A, beta [Source:MGI Symbol;Acc:MGI:1920949]) HSP 1 Score: 158.303 bits (399), Expect = 4.951e-40 Identity = 152/588 (25.85%), Postives = 280/588 (47.62%), Query Frame = 1
Query: 166 IDE-DNIDTAEKLRAFHLLPTVALTLKSENTRTMLIPILETLITTAVDNGDDEALMVIAQKLGDFVPLVGGGNYAGCLLQLLARXXXXXXXXXXXQAACDSLIKIIPTLDSNVVDTNCLQLVRNVFAEDLYCAARKAGVRLIPVCYKIASSESQTELKNRLLHLCMAEDEIPLVRAGAVEQLTDLS-IVAGSVLKPEMIRTLTSLVSDNQRVVRAACVKPLLELGKNVDTNEFDTILFPLLDKLSEDSNRDTRRGVASLISEFQK-IAQKFDKS-LHNLLIKLMEDNEIDARKIVASQLKEFC----AACSHQVLIDFVLPKIREHLNLEREDRVKAELVKSVVTMIPSFKREDSLP-LVQHVLSFLNDSNLQTKQYVFEHFQGLIGLISPSELQLTILPSLFKLFADKNWRIRSGVVASLMLIIPIVDEACCRDTLLPTTLSWLKDPVWNIRQGTCELIGSITGRFPSLLTEKLVKAPIFKELFEDVNYHLRQCWCFLIEAICKSQPKESKSDLLTSFLTNHVNELLLAMISKDQVFNVQISAIRSIKLLSSYLDKNFLHKQXXXXXXXXXXXXXDIDVRDFSDAAL 1902
IDE N D +L + L T+AL L E TRT L+P L I +DE L+ +A++LG+F LVGG ++A CLL L + E +V + A +SL +I ++ + + LV+ + + D + +R + L VCY AS+ + E++ LC D+ P+VR A +L + + ++ +K E++ T+L SD Q VR V+ + + + + + + ++ P L + +ED + R VA SE QK + K S L L+ D E + R A +++E C A V+++ +LP I+E ++ + VK+ L ++ + +E+++ L+ L+ L D + + + + + +I +L ++LP++ +L D WR+R ++ + L+ + + L ++WL D V+ IR+ + + +F + + + P + D NY R F I A+ ++ KE T + ++L M + DQV NV+ + +S++ + LD N L + V + + D+DV+ F+ A+
Sbjct: 29 IDELRNEDVQLRLNSIKKLSTIALALGVERTRTELLPFLTDTIY-----DEDEVLLALAEQLGNFTGLVGGPDFAHCLLPPLESLATVEETVVRDK-AVESLRQISQEHTPVALEAHFVPLVKRLASGDWF-TSRTSACGLFSVCYPRASNAVKAEIRQHFRSLC--SDDTPMVRRAAASKLGEFAKVLELDSVKTEIVPLFTNLASDEQDSVRLLAVEACVSIAQLLSQEDLEALVMPTLRQAAEDKSWRVRYMVADKFSELQKAVGPKIALSDLIPAFQSLLRDCEAEVRAAAAHKVRELCENLPAEGRETVIMNQILPYIKELVS-DTNQHVKSALASVIMGLSTVLGKENTIEHLLPLFLAQLKDECPEVRLNIISNLDCVNEVIGIRQLSQSLLPAIVELAEDAKWRVRLAIIEYMPLLAGQLGVEFFDEKLNSLCMAWLVDHVYAIREAATNNLMKLVQKFGTEWAQNTI-VPKVLVMANDPNYLHRMTTLFCINALSEACGKE--------ITTKQMLPIVLKM-AGDQVANVRFNVAKSLQKIGPILDTNALQGE-VKPVLQKLGQDEDMDVKYFAQEAI 595
BLAST of Serine/threonine-protein phosphatase 2A regulatory subunit A vs. Ensembl Mouse
Match: Ppp2r1a (protein phosphatase 2, regulatory subunit A, alpha [Source:MGI Symbol;Acc:MGI:1926334]) HSP 1 Score: 154.836 bits (390), Expect = 2.529e-39 Identity = 151/590 (25.59%), Postives = 277/590 (46.95%), Query Frame = 1
Query: 160 VNIDE-DNIDTAEKLRAFHLLPTVALTLKSENTRTMLIPILETLITTAVDNGDDEALMVIAQKLGDFVPLVGGGNYAGCLLQLLARXXXXXXXXXXXQAACDSLIKIIPTLDSNVVDTNCLQLVRNVFAEDLYCAARKAGVRLIPVCYKIASSESQTELKNRLLHLCMAEDEIPLVRAGAVEQLTDLS-IVAGSVLKPEMIRTLTSLVSDNQRVVRAACVKPLLELGKNVDTNEFDTILFPLLDKLSEDSNRDTRRGVASLISEFQK-IAQKFDKS-LHNLLIKLMEDNEIDARKIVASQLKEFC----AACSHQVLIDFVLPKIREHLNLEREDRVKAELVKSVVTMIPSFKREDSLP-LVQHVLSFLNDSNLQTKQYVFEHFQGLIGLISPSELQLTILPSLFKLFADKNWRIRSGVVASLMLIIPIVDEACCRDTLLPTTLSWLKDPVWNIRQGTCELIGSITGRFPSLLTEKLVKAPIFKELFEDVNYHLRQCWCFLIEAICKSQPKESKSDLLTSFLTNHVNELLLAMISKDQVFNVQISAIRSIKLLSSYLDKNFLHKQXXXXXXXXXXXXXDIDVRDFSDAAL 1902
V IDE N D +L + L T+AL L E TR+ L+P L I +DE L+ +A++LG F LVGG Y CLL L + E +V +A +SL I + ++ + + LV+ + D + +R + L VCY SS + EL+ +LC D+ P+VR A +L + + ++ +K E+I ++L SD Q VR V+ + + + + + + ++ P L + +ED + R VA +E QK + + K+ L LM+D E + R + ++KEFC A C V++ +LP I+E ++ + VK+ L ++ + P +++++ L+ L+ L D + + + + + +I +L ++LP++ +L D WR+R ++ + L+ + + L ++WL D V+ IR+ + + +F + P + D NY R F I + + ++ T H+ +L M + D V NV+ + +S++ + LD + L + V + + + D+DV+ F+ AL
Sbjct: 15 VLIDELRNEDVQLRLNSIKKLSTIALALGVERTRSELLPFLTDTIY-----DEDEVLLALAEQLGTFTTLVGGPEYVHCLLPPLESLATVEETVVRDKAV-ESLRAISHEHSPSDLEAHFVPLVKRLAGGDWF-TSRTSACGLFSVCYPRVSSAVKAELRQYFRNLC--SDDTPMVRRAAASKLGEFAKVLELDNVKSEIIPMFSNLASDEQDSVRLLAVEACVNIAQLLPQEDLEALVMPTLRQAAEDKSWRVRYMVADKFTELQKAVGPEITKTDLVPAFQNLMKDCEAEVRAAASHKVKEFCENLSADCRENVIMTQILPCIKELVS-DANQHVKSALASVIMGLSPILGKDNTIEHLLPLFLAQLKDECPEVRLNIISNLDCVNEVIGIRQLSQSLLPAIVELAEDAKWRVRLAIIEYMPLLAGQLGVEFFDEKLNSLCMAWLVDHVYAIREAATSNLKKLVEKFGKEWAHATI-IPKVLAMSGDPNYLHRMTTLFCINVLSEVCGQD--------ITTKHMLPTVLRM-AGDPVANVRFNVAKSLQKIGPILDNSTLQSE-VKPILEKLTQDQDVDVKYFAQEAL 583
BLAST of Serine/threonine-protein phosphatase 2A regulatory subunit A vs. UniProt/SwissProt
Match: sp|Q7TNP2|2AAB_MOUSE (Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform OS=Mus musculus OX=10090 GN=Ppp2r1b PE=1 SV=2) HSP 1 Score: 158.688 bits (400), Expect = 9.039e-40 Identity = 153/590 (25.93%), Postives = 281/590 (47.63%), Query Frame = 1
Query: 160 VNIDE-DNIDTAEKLRAFHLLPTVALTLKSENTRTMLIPILETLITTAVDNGDDEALMVIAQKLGDFVPLVGGGNYAGCLLQLLARXXXXXXXXXXXQAACDSLIKIIPTLDSNVVDTNCLQLVRNVFAEDLYCAARKAGVRLIPVCYKIASSESQTELKNRLLHLCMAEDEIPLVRAGAVEQLTDLS-IVAGSVLKPEMIRTLTSLVSDNQRVVRAACVKPLLELGKNVDTNEFDTILFPLLDKLSEDSNRDTRRGVASLISEFQK-IAQKFDKS-LHNLLIKLMEDNEIDARKIVASQLKEFC----AACSHQVLIDFVLPKIREHLNLEREDRVKAELVKSVVTMIPSFKREDSLP-LVQHVLSFLNDSNLQTKQYVFEHFQGLIGLISPSELQLTILPSLFKLFADKNWRIRSGVVASLMLIIPIVDEACCRDTLLPTTLSWLKDPVWNIRQGTCELIGSITGRFPSLLTEKLVKAPIFKELFEDVNYHLRQCWCFLIEAICKSQPKESKSDLLTSFLTNHVNELLLAMISKDQVFNVQISAIRSIKLLSSYLDKNFLHKQXXXXXXXXXXXXXDIDVRDFSDAAL 1902
V IDE N D +L + L T+AL L E TRT L+P L I +DE L+ +A++LG+F LVGG ++A CLL L + E +V +A +SL +I ++ + + LV+ + + D + +R + L VCY AS+ + E++ LC D+ P+VR A +L + + ++ +K E++ T+L SD Q VR V+ + + + + + + ++ P L + +ED + R VA SE QK + K S L L+ D E + R A +++E C A V+++ +LP I+E ++ + VK+ L ++ + +E+++ L+ L+ L D + + + + + +I +L ++LP++ +L D WR+R ++ + L+ + + L ++WL D V+ IR+ + + +F + + + P + D NY R F I A+ ++ KE T + ++L M + DQV NV+ + +S++ + LD N L + V + + D+DV+ F+ A+
Sbjct: 27 VLIDELRNEDVQLRLNSIKKLSTIALALGVERTRTELLPFLTDTIY-----DEDEVLLALAEQLGNFTGLVGGPDFAHCLLPPLESLATVEETVVRDKAV-ESLRQISQEHTPVALEAHFVPLVKRLASGDWF-TSRTSACGLFSVCYPRASNAVKAEIRQHFRSLC--SDDTPMVRRAAASKLGEFAKVLELDSVKTEIVPLFTNLASDEQDSVRLLAVEACVSIAQLLSQEDLEALVMPTLRQAAEDKSWRVRYMVADKFSELQKAVGPKIALSDLIPAFQSLLRDCEAEVRAAAAHKVRELCENLPAEGRETVIMNQILPYIKELVS-DTNQHVKSALASVIMGLSTVLGKENTIEHLLPLFLAQLKDECPEVRLNIISNLDCVNEVIGIRQLSQSLLPAIVELAEDAKWRVRLAIIEYMPLLAGQLGVEFFDEKLNSLCMAWLVDHVYAIREAATNNLMKLVQKFGTEWAQNTI-VPKVLVMANDPNYLHRMTTLFCINALSEACGKE--------ITTKQMLPIVLKM-AGDQVANVRFNVAKSLQKIGPILDTNALQGE-VKPVLQKLGQDEDMDVKYFAQEAI 595
BLAST of Serine/threonine-protein phosphatase 2A regulatory subunit A vs. UniProt/SwissProt
Match: sp|Q4QQT4|2AAB_RAT (Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform OS=Rattus norvegicus OX=10116 GN=Ppp2r1b PE=2 SV=1) HSP 1 Score: 157.918 bits (398), Expect = 1.750e-39 Identity = 152/590 (25.76%), Postives = 281/590 (47.63%), Query Frame = 1
Query: 160 VNIDE-DNIDTAEKLRAFHLLPTVALTLKSENTRTMLIPILETLITTAVDNGDDEALMVIAQKLGDFVPLVGGGNYAGCLLQLLARXXXXXXXXXXXQAACDSLIKIIPTLDSNVVDTNCLQLVRNVFAEDLYCAARKAGVRLIPVCYKIASSESQTELKNRLLHLCMAEDEIPLVRAGAVEQLTDLS-IVAGSVLKPEMIRTLTSLVSDNQRVVRAACVKPLLELGKNVDTNEFDTILFPLLDKLSEDSNRDTRRGVASLISEFQK-IAQKFDKS-LHNLLIKLMEDNEIDARKIVASQLKEFC----AACSHQVLIDFVLPKIREHLNLEREDRVKAELVKSVVTMIPSFKREDSLP-LVQHVLSFLNDSNLQTKQYVFEHFQGLIGLISPSELQLTILPSLFKLFADKNWRIRSGVVASLMLIIPIVDEACCRDTLLPTTLSWLKDPVWNIRQGTCELIGSITGRFPSLLTEKLVKAPIFKELFEDVNYHLRQCWCFLIEAICKSQPKESKSDLLTSFLTNHVNELLLAMISKDQVFNVQISAIRSIKLLSSYLDKNFLHKQXXXXXXXXXXXXXDIDVRDFSDAAL 1902
V IDE N D +L + L T+AL L E TRT L+P L I +DE L+ +A++LG+F LVGG ++A CLL L + E +V + A +SL +I ++ + + LV+ + + D + +R + L VCY AS+ + E++ LC D+ P+VR A +L + + ++ +K E++ T+L SD Q VR V+ + + + + ++ + ++ P L + +ED + R VA SE QK + K S L L+ D E + R A +++E C V+++ +LP I+E ++ + VK+ L ++ + +E+++ L+ L+ L D + + + + + +I +L ++LP++ +L D WR+R ++ + L+ + + L ++WL D V+ IR+ + + +F + + + P + D NY R F I A+ ++ KE T + ++L M + DQV NV+ + +S++ + LD N L + V + + D+DV+ F+ A+
Sbjct: 27 VLIDELRNEDVQLRLNSIKKLSTIALALGVERTRTELLPFLTDTIYD-----EDEVLLALAEQLGNFTGLVGGPDFAHCLLPPLESLATVEETVVRDK-AVESLRQISQEHTPVALEAHFVPLVKRLASGDWF-TSRTSACGLFSVCYPRASNAVKAEIRQHFRSLC--SDDTPMVRRAAASKLGEFAKVLELDSVKTEIVPLFTNLASDEQDSVRLLAVEACVSIAQLLSQDDLEALVMPTLRQAAEDKSWRVRYMVADKFSELQKAVGPKIALSDLIPAFQSLLRDCEAEVRAAAAHKVRELCENLPTEGRETVIMNQILPYIKELVS-DTNQHVKSALASVIMGLSTVLGKENTIEHLLPLFLAQLKDECPEVRLNIISNLDCVNEVIGIRQLSQSLLPAIVELAEDAKWRVRLAIIEYMPLLAGQLGVEFFDEKLNSLCMAWLVDHVYAIREAATNNLMKLVQKFGTEWAQNTI-VPKVLVMANDPNYLHRMTTLFCINALSEACGKE--------ITTKQMLPIVLKM-AGDQVANVRFNVAKSLQKIGPILDTNALQGE-VKPVLQKLGQDEDMDVKYFAQEAI 595
BLAST of Serine/threonine-protein phosphatase 2A regulatory subunit A vs. UniProt/SwissProt
Match: sp|P30153|2AAA_HUMAN (Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform OS=Homo sapiens OX=9606 GN=PPP2R1A PE=1 SV=4) HSP 1 Score: 155.221 bits (391), Expect = 1.346e-38 Identity = 151/590 (25.59%), Postives = 277/590 (46.95%), Query Frame = 1
Query: 160 VNIDE-DNIDTAEKLRAFHLLPTVALTLKSENTRTMLIPILETLITTAVDNGDDEALMVIAQKLGDFVPLVGGGNYAGCLLQLLARXXXXXXXXXXXQAACDSLIKIIPTLDSNVVDTNCLQLVRNVFAEDLYCAARKAGVRLIPVCYKIASSESQTELKNRLLHLCMAEDEIPLVRAGAVEQLTDLS-IVAGSVLKPEMIRTLTSLVSDNQRVVRAACVKPLLELGKNVDTNEFDTILFPLLDKLSEDSNRDTRRGVASLISEFQK-IAQKFDKS-LHNLLIKLMEDNEIDARKIVASQLKEFC----AACSHQVLIDFVLPKIREHLNLEREDRVKAELVKSVVTMIPSFKREDSLP-LVQHVLSFLNDSNLQTKQYVFEHFQGLIGLISPSELQLTILPSLFKLFADKNWRIRSGVVASLMLIIPIVDEACCRDTLLPTTLSWLKDPVWNIRQGTCELIGSITGRFPSLLTEKLVKAPIFKELFEDVNYHLRQCWCFLIEAICKSQPKESKSDLLTSFLTNHVNELLLAMISKDQVFNVQISAIRSIKLLSSYLDKNFLHKQXXXXXXXXXXXXXDIDVRDFSDAAL 1902
V IDE N D +L + L T+AL L E TR+ L+P L I +DE L+ +A++LG F LVGG Y CLL L + E +V +A +SL I + ++ + + LV+ + D + +R + L VCY SS + EL+ +LC D+ P+VR A +L + + ++ +K E+I ++L SD Q VR V+ + + + + + + ++ P L + +ED + R VA +E QK + + K+ L LM+D E + R + ++KEFC A C V++ +LP I+E ++ + VK+ L ++ + P +++++ L+ L+ L D + + + + + +I +L ++LP++ +L D WR+R ++ + L+ + + L ++WL D V+ IR+ + + +F + P + D NY R F I + + ++ T H+ +L M + D V NV+ + +S++ + LD + L + V + + + D+DV+ F+ AL
Sbjct: 15 VLIDELRNEDVQLRLNSIKKLSTIALALGVERTRSELLPFLTDTIY-----DEDEVLLALAEQLGTFTTLVGGPEYVHCLLPPLESLATVEETVVRDKAV-ESLRAISHEHSPSDLEAHFVPLVKRLAGGDWF-TSRTSACGLFSVCYPRVSSAVKAELRQYFRNLC--SDDTPMVRRAAASKLGEFAKVLELDNVKSEIIPMFSNLASDEQDSVRLLAVEACVNIAQLLPQEDLEALVMPTLRQAAEDKSWRVRYMVADKFTELQKAVGPEITKTDLVPAFQNLMKDCEAEVRAAASHKVKEFCENLSADCRENVIMSQILPCIKELVS-DANQHVKSALASVIMGLSPILGKDNTIEHLLPLFLAQLKDECPEVRLNIISNLDCVNEVIGIRQLSQSLLPAIVELAEDAKWRVRLAIIEYMPLLAGQLGVEFFDEKLNSLCMAWLVDHVYAIREAATSNLKKLVEKFGKEWAHATI-IPKVLAMSGDPNYLHRMTTLFCINVLSEVCGQD--------ITTKHMLPTVLRM-AGDPVANVRFNVAKSLQKIGPILDNSTLQSE-VKPILEKLTQDQDVDVKYFAQEAL 583
BLAST of Serine/threonine-protein phosphatase 2A regulatory subunit A vs. UniProt/SwissProt
Match: sp|P54612|2AAA_PIG (Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform OS=Sus scrofa OX=9823 GN=PPP2R1A PE=2 SV=2) HSP 1 Score: 154.836 bits (390), Expect = 1.769e-38 Identity = 151/590 (25.59%), Postives = 277/590 (46.95%), Query Frame = 1
Query: 160 VNIDE-DNIDTAEKLRAFHLLPTVALTLKSENTRTMLIPILETLITTAVDNGDDEALMVIAQKLGDFVPLVGGGNYAGCLLQLLARXXXXXXXXXXXQAACDSLIKIIPTLDSNVVDTNCLQLVRNVFAEDLYCAARKAGVRLIPVCYKIASSESQTELKNRLLHLCMAEDEIPLVRAGAVEQLTDLS-IVAGSVLKPEMIRTLTSLVSDNQRVVRAACVKPLLELGKNVDTNEFDTILFPLLDKLSEDSNRDTRRGVASLISEFQK-IAQKFDKS-LHNLLIKLMEDNEIDARKIVASQLKEFC----AACSHQVLIDFVLPKIREHLNLEREDRVKAELVKSVVTMIPSFKREDSLP-LVQHVLSFLNDSNLQTKQYVFEHFQGLIGLISPSELQLTILPSLFKLFADKNWRIRSGVVASLMLIIPIVDEACCRDTLLPTTLSWLKDPVWNIRQGTCELIGSITGRFPSLLTEKLVKAPIFKELFEDVNYHLRQCWCFLIEAICKSQPKESKSDLLTSFLTNHVNELLLAMISKDQVFNVQISAIRSIKLLSSYLDKNFLHKQXXXXXXXXXXXXXDIDVRDFSDAAL 1902
V IDE N D +L + L T+AL L E TR+ L+P L I +DE L+ +A++LG F LVGG Y CLL L + E +V +A +SL I + ++ + + LV+ + D + +R + L VCY SS + EL+ +LC D+ P+VR A +L + + ++ +K E+I ++L SD Q VR V+ + + + + + + ++ P L + +ED + R VA +E QK + + K+ L LM+D E + R + ++KEFC A C V++ +LP I+E ++ + VK+ L ++ + P +++++ L+ L+ L D + + + + + +I +L ++LP++ +L D WR+R ++ + L+ + + L ++WL D V+ IR+ + + +F + P + D NY R F I + + ++ T H+ +L M + D V NV+ + +S++ + LD + L + V + + + D+DV+ F+ AL
Sbjct: 15 VLIDELRNEDVQLRLNSIKKLSTIALALGVERTRSELLPFLTDTIY-----DEDEVLLALAEQLGTFTTLVGGPEYVHCLLPPLESLATVEETVVRDKAV-ESLRAISHEHSPSDLEAHFVPLVKRLAGGDWF-TSRTSACGLFSVCYPRVSSAVKAELRQYFRNLC--SDDTPMVRRAAASKLGEFAKVLELDNVKSEIIPMFSNLASDEQDSVRLLAVEACVNIAQLLPQEDLEALVMPTLRQAAEDKSWRVRYMVADKFTELQKAVGPEITKTDLVPAFQNLMKDCEAEVRAAASHKVKEFCENLSADCRENVIMTQILPCIKELVS-DANQHVKSALASVIMGLSPILGKDNTIEHLLPLFLAQLKDECPEVRLNIISNLDCVNEVIGIRQLSQSLLPAIVELAEDAKWRVRLAIIEYMPLLAGQLGVEFFDEKLNSLCMAWLVDHVYAIREAATSNLKKLVEKFGKEWAHATI-IPKVLAMSGDPNYLHRMTTLFCINVLSEVCGQD--------ITTKHMLPTVLRM-AGDPVANVRFNVAKSLQKIGPILDNSTLQSE-VKPILEKLTQDQDVDVKYFAQEAL 583
BLAST of Serine/threonine-protein phosphatase 2A regulatory subunit A vs. UniProt/SwissProt
Match: sp|Q76MZ3|2AAA_MOUSE (Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform OS=Mus musculus OX=10090 GN=Ppp2r1a PE=1 SV=3) HSP 1 Score: 154.836 bits (390), Expect = 1.769e-38 Identity = 151/590 (25.59%), Postives = 277/590 (46.95%), Query Frame = 1
Query: 160 VNIDE-DNIDTAEKLRAFHLLPTVALTLKSENTRTMLIPILETLITTAVDNGDDEALMVIAQKLGDFVPLVGGGNYAGCLLQLLARXXXXXXXXXXXQAACDSLIKIIPTLDSNVVDTNCLQLVRNVFAEDLYCAARKAGVRLIPVCYKIASSESQTELKNRLLHLCMAEDEIPLVRAGAVEQLTDLS-IVAGSVLKPEMIRTLTSLVSDNQRVVRAACVKPLLELGKNVDTNEFDTILFPLLDKLSEDSNRDTRRGVASLISEFQK-IAQKFDKS-LHNLLIKLMEDNEIDARKIVASQLKEFC----AACSHQVLIDFVLPKIREHLNLEREDRVKAELVKSVVTMIPSFKREDSLP-LVQHVLSFLNDSNLQTKQYVFEHFQGLIGLISPSELQLTILPSLFKLFADKNWRIRSGVVASLMLIIPIVDEACCRDTLLPTTLSWLKDPVWNIRQGTCELIGSITGRFPSLLTEKLVKAPIFKELFEDVNYHLRQCWCFLIEAICKSQPKESKSDLLTSFLTNHVNELLLAMISKDQVFNVQISAIRSIKLLSSYLDKNFLHKQXXXXXXXXXXXXXDIDVRDFSDAAL 1902
V IDE N D +L + L T+AL L E TR+ L+P L I +DE L+ +A++LG F LVGG Y CLL L + E +V +A +SL I + ++ + + LV+ + D + +R + L VCY SS + EL+ +LC D+ P+VR A +L + + ++ +K E+I ++L SD Q VR V+ + + + + + + ++ P L + +ED + R VA +E QK + + K+ L LM+D E + R + ++KEFC A C V++ +LP I+E ++ + VK+ L ++ + P +++++ L+ L+ L D + + + + + +I +L ++LP++ +L D WR+R ++ + L+ + + L ++WL D V+ IR+ + + +F + P + D NY R F I + + ++ T H+ +L M + D V NV+ + +S++ + LD + L + V + + + D+DV+ F+ AL
Sbjct: 15 VLIDELRNEDVQLRLNSIKKLSTIALALGVERTRSELLPFLTDTIY-----DEDEVLLALAEQLGTFTTLVGGPEYVHCLLPPLESLATVEETVVRDKAV-ESLRAISHEHSPSDLEAHFVPLVKRLAGGDWF-TSRTSACGLFSVCYPRVSSAVKAELRQYFRNLC--SDDTPMVRRAAASKLGEFAKVLELDNVKSEIIPMFSNLASDEQDSVRLLAVEACVNIAQLLPQEDLEALVMPTLRQAAEDKSWRVRYMVADKFTELQKAVGPEITKTDLVPAFQNLMKDCEAEVRAAASHKVKEFCENLSADCRENVIMTQILPCIKELVS-DANQHVKSALASVIMGLSPILGKDNTIEHLLPLFLAQLKDECPEVRLNIISNLDCVNEVIGIRQLSQSLLPAIVELAEDAKWRVRLAIIEYMPLLAGQLGVEFFDEKLNSLCMAWLVDHVYAIREAATSNLKKLVEKFGKEWAHATI-IPKVLAMSGDPNYLHRMTTLFCINVLSEVCGQD--------ITTKHMLPTVLRM-AGDPVANVRFNVAKSLQKIGPILDNSTLQSE-VKPILEKLTQDQDVDVKYFAQEAL 583
BLAST of Serine/threonine-protein phosphatase 2A regulatory subunit A vs. TrEMBL
Match: A0A4V3SGI6 (Uncharacterized protein (Fragment) OS=Opisthorchis felineus OX=147828 GN=CRM22_002052 PE=4 SV=1) HSP 1 Score: 479.174 bits (1232), Expect = 3.046e-156 Identity = 238/461 (51.63%), Postives = 332/461 (72.02%), Query Frame = 1
Query: 193 EKLRAFHLLPTVALTLKSENTRTMLIPILETLITTAVDNGDDEALMVIAQKLGDFVPLVGGGNYAGCLLQLLARXXXXXXXXXXXQAACDSLIKIIPTLDSNVVDTNCLQLVRNVFAEDLYCAARKAGVRLIPVCYKIASSESQTELKNRLLHLCMAEDEIPLVRAGAVEQLTDLSIVAGSVLKPEMIRTLTSLVSDNQRVVRAACVKPLLELGKNV-DTNEFDTILFPLLDKLSEDSNRDTRRGVASLISEFQKIAQKFD---KSLHNLLIKLMEDNEIDARKIVASQLKEFCAACSHQVLIDFVLPKIREHLNLEREDRVKAELVKSVVTMIPSFKREDSLPLVQHVLSFLNDSNLQTKQYVFEHFQGLIGLISPSELQLTILPSLFKLFADKNWRIRSGVVASLMLIIPIVDEACCRDTLLPTTLSWLKDPVWNIRQGTCELIGSITGRFPSLLTEKL 1563
EKL+ F+ LPT+A +L TR L+P + L+T A++ GDDE L+VIAQ LG F LVGG ++A CLL +L +II CVEE+VV QAACD+L++IIP L V+ C+ ++R + EDLYCA+RK +LI CY + S++ QT+LK R+ HL ++DE+PLVRA AV+QL DLS + GS LK E+ LTSLVSDNQRVVRAACV PL+ELG+ V D NEFD+ + P +DKL+ D+ RDTRR +A I+ Q++A F +SLH +++ L+EDNE++ R++ +QLK+FC A +L+ +LP++REHL +ERE+ V+AELV+ V+++PS REDS+PLVQH+L+FLND++ Q+KQYVFEHF LI LI +++QLT+LPSL +L+ D+NWR+R GVV S+ + + EAC RDT+LP L+WL+DP W +R+ C + + FP L E L
Sbjct: 1 EKLKVFYSLPTIAASLGPNETREKLVPTIAELVTNAINAGDDEVLLVIAQTLGGFTELVGGKDHASCLLPILEKIISCVEEVVVAQAACDALVEIIPKLPMEVIQEKCVGMIRRILEEDLYCASRKVTCKLITTCYPLVSAKFQTDLKYRIFHLADSDDEVPLVRAAAVQQLVDLSKLIGSELKTELCLLLTSLVSDNQRVVRAACVGPLVELGRMVTDPNEFDSAVRPCIDKLASDTTRDTRRAMAESITPLQQVACGFGGSTRSLHQIMLSLLEDNEMETRRVATTQLKDFCLASPPDILVGVLLPQLREHLVVEREEPVRAELVRCAVSLLPSISREDSIPLVQHILAFLNDTSSQSKQYVFEHFSDLITLIPATDVQLTLLPSLVRLWQDRNWRVRLGVVQSVPCLYQSLPEACVRDTVLPANLAWLRDPSWYVRECACRSLARLLRVFPGLCKEVL 461
BLAST of Serine/threonine-protein phosphatase 2A regulatory subunit A vs. TrEMBL
Match: G7YB72 (Probable serine/threonine-protein phosphatase PP2A regulatory subunit (Fragment) OS=Clonorchis sinensis OX=79923 GN=CLF_104231 PE=4 SV=1) HSP 1 Score: 476.478 bits (1225), Expect = 1.236e-152 Identity = 238/461 (51.63%), Postives = 331/461 (71.80%), Query Frame = 1
Query: 193 EKLRAFHLLPTVALTLKSENTRTMLIPILETLITTAVDNGDDEALMVIAQKLGDFVPLVGGGNYAGCLLQLLARXXXXXXXXXXXQAACDSLIKIIPTLDSNVVDTNCLQLVRNVFAEDLYCAARKAGVRLIPVCYKIASSESQTELKNRLLHLCMAEDEIPLVRAGAVEQLTDLSIVAGSVLKPEMIRTLTSLVSDNQRVVRAACVKPLLELGKNV-DTNEFDTILFPLLDKLSEDSNRDTRRGVASLISEFQKIAQKFD---KSLHNLLIKLMEDNEIDARKIVASQLKEFCAACSHQVLIDFVLPKIREHLNLEREDRVKAELVKSVVTMIPSFKREDSLPLVQHVLSFLNDSNLQTKQYVFEHFQGLIGLISPSELQLTILPSLFKLFADKNWRIRSGVVASLMLIIPIVDEACCRDTLLPTTLSWLKDPVWNIRQGTCELIGSITGRFPSLLTEKL 1563
EKL+ F LPT+A +L TR L+P + L+T A++ GDDE L+VIAQ LG F LVGG ++A CLL +L +II CVEE+VV QAACD+L++IIP L V+ C+ ++R + EDLYCA+RK +LI CY + S++ QT+LK R+ HL ++DE+PLVRA AV+QL DLS + GS LK E+ LTSLVSDNQRVVRAACV PL+ELG+ V D NEFD+ + P +DKL+ D+ RDTRR +A I+ Q++A F +SLH +++ L+EDNE++ R++ +QLK+FC A +L+ +LP++REHL +ERE+ V+AELV+ V+++PS REDS+PLVQH+L+FLND++ Q+KQYVFEHF LI LI +++QLT+LPSL +L+ D+NWR+R GVV S+ + + EAC RDT+LP L+WL+DP W +R+ C + + FP L E L
Sbjct: 1 EKLKVFCSLPTIAASLGPNETREKLVPTIAELVTNAINAGDDEVLLVIAQTLGGFTELVGGKDHASCLLPILEKIISCVEEVVVAQAACDALVEIIPKLPMEVIQEKCVGMIRRILEEDLYCASRKVTCKLITTCYPLVSAKFQTDLKYRIFHLADSDDEVPLVRAAAVQQLVDLSKLIGSELKTELCLLLTSLVSDNQRVVRAACVGPLVELGRMVTDPNEFDSAVRPCIDKLASDTTRDTRRAMAESITPLQQVACGFGGSTRSLHQIMLSLLEDNEVETRRVATTQLKDFCLASPPDILVGVLLPQLREHLVVEREEPVRAELVRCAVSLLPSISREDSIPLVQHILAFLNDTSSQSKQYVFEHFSDLITLIPATDVQLTLLPSLVRLWQDRNWRVRLGVVQSVPCLYQSLPEACVRDTVLPANLAWLRDPSWYVRECACRSLARLLRVFPGLCKEVL 461
BLAST of Serine/threonine-protein phosphatase 2A regulatory subunit A vs. TrEMBL
Match: A0A074Z353 (Uncharacterized protein (Fragment) OS=Opisthorchis viverrini OX=6198 GN=T265_15075 PE=4 SV=1) HSP 1 Score: 451.055 bits (1159), Expect = 1.947e-144 Identity = 225/430 (52.33%), Postives = 313/430 (72.79%), Query Frame = 1
Query: 286 LITTAVDNGDDEALMVIAQKLGDFVPLVGGGNYAGCLLQLLARXXXXXXXXXXXQAACDSLIKIIPTLDSNVVDTNCLQLVRNVFAEDLYCAARKAGVRLIPVCYKIASSESQTELKNRLLHLCMAEDEIPLVRAGAVEQLTDLSIVAGSVLKPEMIRTLTSLVSDNQRVVRAACVKPLLELGKNV-DTNEFDTILFPLLDKLSEDSNRDTRRGVASLISEFQKIAQKFD---KSLHNLLIKLMEDNEIDARKIVASQLKEFCAACSHQVLIDFVLPKIREHLNLEREDRVKAELVKSVVTMIPSFKREDSLPLVQHVLSFLNDSNLQTKQYVFEHFQGLIGLISPSELQLTILPSLFKLFADKNWRIRSGVVASLMLIIPIVDEACCRDTLLPTTLSWLKDPVWNIRQGTCELIGSITGRFPSLLTEKL 1563
L+T A++ GDDE L+VIAQ LG F LVGG ++A CLL +L +II CVEE+VV QAACD+L++IIP L V+ C+ ++R + EDLYCA+RK +LI CY + S++ QT+LK R+ HL ++DE+PLVRA AV+QL DLS + GS LK E+ LTSLVSDNQRVVRAACV PL+ELG+ V D NEFD+ + P +DKL+ D+ RDTRR +A I+ Q++A F +SLH +++ L+EDNE++ R++ +QLK+FC A +L+ +LP++REHL +ERE+ V+AELV+ V+++PS REDS+PLVQH+L+FLND++ Q+KQYVFEHF LI LI +++QLT+LPSL +L+ D+NWR+R GVV S+ + + EAC RDT+LP L+WL+DP W +R+ C + + FP L E L
Sbjct: 3 LVTNAINAGDDEVLLVIAQTLGGFSELVGGKDHASCLLPILEKIISCVEEVVVAQAACDALVEIIPKLPMEVIQEKCVGMIRRILEEDLYCASRKVTCKLITTCYPLVSAKFQTDLKYRIFHLADSDDEVPLVRAAAVQQLVDLSKLIGSELKTELCLLLTSLVSDNQRVVRAACVGPLVELGRMVTDPNEFDSAVRPCIDKLASDTTRDTRRAMAESITLLQQVACGFGGSTRSLHQIMLSLLEDNEVETRRVATTQLKDFCLASPPDILVGVLLPQLREHLVVEREEPVRAELVRCAVSLLPSISREDSIPLVQHILAFLNDTSSQSKQYVFEHFSDLITLIPATDVQLTLLPSLVRLWQDRNWRVRLGVVQSVPCLYQSLPEACVRDTVLPANLAWLRDPSWYVRECACRSLARLLRVFPGLCKEVL 432
BLAST of Serine/threonine-protein phosphatase 2A regulatory subunit A vs. TrEMBL
Match: A0A5K4F325 (Uncharacterized protein OS=Schistosoma mansoni OX=6183 PE=4 SV=1) HSP 1 Score: 435.261 bits (1118), Expect = 5.543e-139 Identity = 229/483 (47.41%), Postives = 337/483 (69.77%), Query Frame = 1
Query: 73 VENIIQTLKGFCVSYNNNSAIDGVEQKKIVNIDEDNIDTAEKLRAFHLLPTVALTLKSENTRTMLIPILETLITTAVDNGDDEALMVIAQKLGDFVPLVGGGNYAGCLLQLLARXXXXXXXXXXXQAACDSLIKIIPTLDSNVVDTNCLQLVRNVFAEDLYCAARKAGVRLIPVCYKIASSESQTELKNRLLHLCMAEDEIPLVRAGAVEQLTDLSIVAGSVLKPEMIRTLTSLVSDNQRVVRAACVKPLLELGKNV-DTNEFDTILFPLLDKLSEDSNRDTRRGVASLISEFQKIA---QKFDKSLHNLLIKLMEDNEIDARKIVASQLKEFCAACSHQVLIDFVLPKIREHLNLEREDRVKAELVKSVVTMIPSFKREDSLPLVQHVLSFLNDSNLQTKQYVFEHFQGLIGLISPSELQLTILPSLFKLFADKNWRIRSGVVASLMLIIPIVDEACCRDTLLPTTLSWLKDPVWNIRQGTC 1509
+E ++QTLK + ++N++A + + +N++ +EKLR FH LPT+A +L +TR LIP + +++ A+D GDDE LMVIAQKLG F LVGG + ++ +LA II +EE+VV +AAC+SLI ++P L ++VVD+ ++R++ EDLYCA+RK +LI CY + S+ +Q + K RL HL +EDE+PLVRA AV+QL L+ + G LK E+ L SLVSDNQRVVRAAC+ PL+ELG+ + D EFD+ + P +DKL+ D +RD RR +AS+I+ Q + +SLH ++ L+EDNE++ R+I A QLK+FC A +L+ +LP++REHL++ERE+RV++ELV+ V ++PS +RED LPLVQH+L FLND++ Q+KQYVFEHF L+ L+ +E+QLT+LPSL +L+ DKNWR+R GVV S+ + + E C ++T+LP L+WL+DP W +R+ C
Sbjct: 4 LEAVLQTLK--TLRFDNSTA-----SSNTSDAEYENLEASEKLRVFHTLPTLASSLGPVDTREKLIPTISDVVSNAIDAGDDEILMVIAQKLGSFGDLVGGAEHIPLIVPILANIIYSIEEVVVAEAACNSLIALLPKLPNDVVDSTFAPIIRHIIEEDLYCASRKVVTKLIIACYPMVSARNQVDFKYRLFHLADSEDEVPLVRAAAVQQLVPLAKLFGPELKSELGLLLASLVSDNQRVVRAACLPPLVELGRMITDAAEFDSTVRPCIDKLAGDPSRDVRRAMASVITNLQTLVCNHGGASRSLHQTMLNLLEDNEVETRRISAGQLKDFCLASPKDILVTVLLPRLREHLSMEREERVRSELVRCAVGLLPSIRREDCLPLVQHILGFLNDTSSQSKQYVFEHFSELVALMPANEIQLTLLPSLLRLWQDKNWRVRLGVVQSVPCLYDKLPENCLQETVLPANLAWLRDPAWCVRECAC 479
BLAST of Serine/threonine-protein phosphatase 2A regulatory subunit A vs. TrEMBL
Match: A0A4Z2DVR9 (Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform OS=Schistosoma japonicum OX=6182 GN=EWB00_003743 PE=4 SV=1) HSP 1 Score: 427.172 bits (1097), Expect = 8.538e-136 Identity = 225/483 (46.58%), Postives = 332/483 (68.74%), Query Frame = 1
Query: 73 VENIIQTLKGFCVSYNNNSAIDGVEQKKIVNIDEDNIDTAEKLRAFHLLPTVALTLKSENTRTMLIPILETLITTAVDNGDDEALMVIAQKLGDFVPLVGGGNYAGCLLQLLARXXXXXXXXXXXQAACDSLIKIIPTLDSNVVDTNCLQLVRNVFAEDLYCAARKAGVRLIPVCYKIASSESQTELKNRLLHLCMAEDEIPLVRAGAVEQLTDLSIVAGSVLKPEMIRTLTSLVSDNQRVVRAACVKPLLELGKNV-DTNEFDTILFPLLDKLSEDSNRDTRRGVASLISEFQKIA---QKFDKSLHNLLIKLMEDNEIDARKIVASQLKEFCAACSHQVLIDFVLPKIREHLNLEREDRVKAELVKSVVTMIPSFKREDSLPLVQHVLSFLNDSNLQTKQYVFEHFQGLIGLISPSELQLTILPSLFKLFADKNWRIRSGVVASLMLIIPIVDEACCRDTLLPTTLSWLKDPVWNIRQGTC 1509
VE ++QTLK ++ +A + + +N++ +E+LR FH LPT+A L NTR LIP + +++ A+D DDE LMVIAQKLG F LVGG ++ ++ +LA II +EE+VV +AACDSL+ ++P L ++VVD+ ++R++ EDLYCA+RK +LI CY + S+ +Q + K RL HL +EDE+PLVRA AV+QL L+ AGS LK E+ + SLVSDNQRVVRAAC+ PL+ELG+ + D EF++ + P +DKL+ D +RD RRG+A++I+ Q + +SLH +++ L+EDNE + R+I A Q K+FC A +L+ +LP++RE L++ERE+RV++ELV+ V ++PS RED LPLVQH+L+FLND+ Q+KQYVFEHF L+ L+ +E+QLT+LPSL +L+ DKNWR+R GVV S+ + + + C ++T+LP L+WL+DP W +R+ C
Sbjct: 4 VEAVLQTLKTL--RFDTPTA-----PSNTTDSEYENLEISERLRVFHTLPTLASNLGPVNTREKLIPTISDVVSNAIDADDDEVLMVIAQKLGSFGDLVGGADHVSLIVPILANIIYSIEEVVVSEAACDSLVALLPKLPNDVVDSTFAPIIRHIIEEDLYCASRKVVTKLIIACYPLVSTRNQVDFKYRLFHLADSEDEVPLVRAAAVQQLVPLARFAGSDLKSELGLLIASLVSDNQRVVRAACLPPLVELGRMITDAAEFESTVRPCIDKLAGDPSRDVRRGMATVITNLQTLVCNHGGASRSLHQIMLNLLEDNETETRRISAGQFKDFCLASPKDILVTILLPRLRERLSMEREERVRSELVRCAVGLLPSINREDCLPLVQHILAFLNDTCSQSKQYVFEHFSELVALMPANEIQLTLLPSLLRLWQDKNWRVRLGVVQSVPCLYDKLPDNCLQETVLPANLAWLRDPAWCVRECAC 479
BLAST of Serine/threonine-protein phosphatase 2A regulatory subunit A vs. Ensembl Cavefish
Match: ppp2r1ba (serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform [Source:NCBI gene;Acc:103032850]) HSP 1 Score: 160.614 bits (405), Expect = 1.744e-41 Identity = 156/589 (26.49%), Postives = 284/589 (48.22%), Query Frame = 1
Query: 166 IDE-DNIDTAEKLRAFHLLPTVALTLKSENTRTMLIPILETLITTAVDNGDDEALMVIAQKLGDFVPLVGGGNYAGCLLQLLARXXXXXXXXXXXQAACDSLIKIIPTLDSNVVDTNCLQLVRNVFAEDLYCAARKAGVRLIPVCYKIASSESQTELKNRLLHLCMAEDEIPLVRAGAVEQLTDLS-IVAGSVLKPEMIRTLTSLVSDNQRVVRAACVKPLLELGKNVDTNEFDTILFPLLDKLSEDSNRDTRRGVASLISEFQK-IAQKFDKS-LHNLLIKLMEDNEIDARKIVASQLKEFCAA----CSHQVLIDFVLPKIREHLNLEREDRVKAELVKSVVTMIPSFKREDSLP-LVQHVLSFLNDSNLQTKQYVFEHFQGLIGLISPSELQLTILPSLFKLFADKNWRIRSGVVASLMLIIPIVDEACCRDTLLPTTLSWLKDPVWNIRQ-GTCELIGSITGRFPSLLTEKLVKAPIFKELFEDVNYHLRQCWCFLIEAICKSQPKESKSDLLTSFLTNHVNELLLAMISKDQVFNVQISAIRSIKLLSSYLDKNFLHKQXXXXXXXXXXXXXDIDVRDFSDAAL 1902
IDE N D +L + L T+AL L E TRT L+P L I +DE L+ +A++LG+F LVGG Y CLL L + E +V +A +SL KI ++ + LV+ + + D + +R + L VCY SS + E++ +LC D+ P+VR A +L + + ++ +K ++I T+L SD Q VR V+ + + + + +T++ P L + +ED + R VA SE QK + + K+ L L++D E + R A+++KEFC +++ +LP ++E ++ + VK+ L ++ + +++++ L+ L+ L D + + + + + +I +L ++LP++ +L D WR+R ++ + L+ + + L ++WL D V+ IR+ TC L + +F + + + P + D NY R F I A+ ++ +E T H+ ++L M S DQV NV+ + +S++ + LD N L + V + + ++ DIDV+ F+ A+
Sbjct: 17 IDELRNEDVQLRLNSIKKLSTIALALGVERTRTELLPFLTDTIY-----DEDEVLLALAEQLGNFTMLVGGPEYVHCLLPPLESLATVEETVVRDKAV-ESLRKISHEHSPVDLEVHFEPLVKRLASGDWF-TSRTSACGLFSVCYPRVSSTVKAEIRQHFRNLC--SDDTPMVRRAAASKLGEFAKVLELEYVKSDIISLFTALASDEQDSVRLLAVEACVSIATLLPQEDLETLVMPTLRQAAEDKSWRVRYMVADKFSELQKAVGPEITKNDLVPAFQNLLKDCEAEVRAAAANKVKEFCENLPEDSRETIIMTHILPCVKELVS-DTNQHVKSALASVIMGLSTILGKDNTIEHLLPLFLAQLKDECPEVRLNIISNLDCVNEVIGIRQLSQSLLPAIVELAEDAKWRVRLAIIEYMPLLAGQLGVEFFDEKLNSLCMAWLVDHVYAIREAATCNLT-KLVEKFGAEWAQNTI-VPKVLGMANDPNYLHRMTTLFCINALSEACGQE--------ITTKHMLPVVLKM-SNDQVANVRFNVAKSLQKIGPVLDSNCLQAE-VKPVLEKLAADQDIDVKYFAQEAV 583
BLAST of Serine/threonine-protein phosphatase 2A regulatory subunit A vs. Ensembl Cavefish
Match: ppp2r1bb (protein phosphatase 2, regulatory subunit A, beta b [Source:ZFIN;Acc:ZDB-GENE-040927-20]) HSP 1 Score: 150.214 bits (378), Expect = 5.848e-38 Identity = 153/593 (25.80%), Postives = 278/593 (46.88%), Query Frame = 1
Query: 166 IDE-DNIDTAEKLRAFHLLPTVALTLKSENTRTMLIPILETLITTAVDNGDDEALMVIAQKLGDFVPLVGGGNYAGCLLQLLARXXXXXXXXXXXQAACDSLIKIIPTLDSNVVDTNCLQLVRNVFAEDLYCAARKAGVRLIPVCYKIASSESQTELKNRLLHLCMAEDEIPLVRAGAVEQLTDLSIVAGSVLKPEMIRTLTSLVSDNQRVVRAACVKPLLELGKNVDTNEFDTILFPLLDKLSEDSNRDTRRGVASLISEFQK-IAQKFDKS-LHNLLIKLMEDNEIDARKIVASQLKEFCAA----CSHQVLIDFVLPKIREHLNLEREDRVKAELVKSVVTMIPSFKREDSLPLVQHVLSF----LNDSNLQTKQYVFEHFQGLIGLISPSELQLTILPSLFKLFADKNWRIRSGVVASLMLIIPIVDEACCRDTLLPTTLSWLKDPVWNIRQ-GTCELIGSITGRFPSLLTEKLVKAPIFKELFEDVNYHLRQCWCFLIEAICKSQPKESKSDLLTSFLTNHVNELLLAMISKDQVFNVQISAIRSIKLLSSYLDKNFLHKQXXXXXXXXXXXXXDIDVRDFSDAALKG 1908
IDE N D +L + L T+AL L E TRT L+P L I +DE L+ +A++LG+F LVGG Y CLL L + E +V +A +SL KI ++ + LV+ + + D + +R + L VCY SS + E++ LC D+ P+ ++ +K ++I T+L SD Q VR V+ + + + + +T++ P L + +ED + R VA SE QK + + K+ L L++D E + R A+++KEFC +++ VLP ++E ++ + VK+ L ++ + ++++ V+H+L L D + + + + + +I +L ++LP++ +L D WR+R ++ + L+ + + L ++WL D V+ IR+ TC L+ + +F + + + P + D NY R F I A+ ++ +E T H+ ++L M S DQV NV+ + +S++ + +D N L + V + + ++ D+DV+ F+ A+ G
Sbjct: 17 IDELRNEDVQLRLNSIKKLSTIALALGVERTRTELLPFLTDTIY-----DEDEVLLALAEQLGNFTMLVGGPEYVHCLLPPLESLATVEETVVRDKAV-ESLRKISQEHSPVDLEVHFEPLVKRLASGDWF-TSRTSACGLFSVCYPRVSSTVKAEIRQHFRTLC--SDDTPMFA----------KVLELDYVKSDIIPLFTALASDEQDSVRLLAVEACVSIATLLPQEDLETLVMPTLRQAAEDKSWRVRYMVADKFSELQKAVGPEITKNDLVPAFQNLLKDCEAEVRAAAANKVKEFCENLPEDSRENIIMTHVLPCVKELVS-DTNQHVKSALASVIMGLSTILGKDNT---VEHLLPLFLAQLKDECPEVRLNIISNLDCVNEVIGIRQLSQSLLPAIVELAEDAKWRVRLAIIEYMPLLAGQLGVEFFDEKLNSLCMAWLVDHVYAIREAATCNLM-KLVEKFGAEWAQNTI-VPKVLGMANDPNYLHRMTTLFCINALSEACGQE--------ITTKHMLPVVLKM-SNDQVANVRFNVAKSLQKIGPVIDSNALQTE-VKPVLEKLATDQDMDVKYFAQEAISG 574
BLAST of Serine/threonine-protein phosphatase 2A regulatory subunit A vs. Ensembl Sea Lamprey
Match: PPP2R1A (protein phosphatase 2 scaffold subunit Aalpha [Source:HGNC Symbol;Acc:HGNC:9302]) HSP 1 Score: 149.828 bits (377), Expect = 1.770e-38 Identity = 144/588 (24.49%), Postives = 274/588 (46.60%), Query Frame = 1
Query: 166 IDE-DNIDTAEKLRAFHLLPTVALTLKSENTRTMLIPILETLITTAVDNGDDEALMVIAQKLGDFVPLVGGGNYAGCLLQLLARXXXXXXXXXXXQAACDSLIKIIPTLDSNVVDTNCLQLVRNVFAEDLYCAARKAGVRLIPVCYKIASSESQTELKNRLLHLCMAEDEIPLVRAGAVEQLTDLS-IVAGSVLKPEMIRTLTSLVSDNQRVVRAACVKPLLELGKNVDTNEFDTILFPLLDKLSEDSNRDTRRGVASLISEFQK-IAQKFDKS-LHNLLIKLMEDNEIDARKIVASQLKEFC----AACSHQVLIDFVLPKIREHLNLEREDRVKAELVKSVVTMIPSFKREDSLP-LVQHVLSFLNDSNLQTKQYVFEHFQGLIGLISPSELQLTILPSLFKLFADKNWRIRSGVVASLMLIIPIVDEACCRDTLLPTTLSWLKDPVWNIRQGTCELIGSITGRFPSLLTEKLVKAPIFKELFEDVNYHLRQCWCFLIEAICKSQPKESKSDLLTSFLTNHVNELLLAMISKDQVFNVQISAIRSIKLLSSYLDKNFLHKQXXXXXXXXXXXXXDIDVRDFSDAAL 1902
IDE N D +L + L T+AL L E TR+ LIP L I +DE L+ +A++LG F LVGG Y CLL L + E +V +A +SL I ++ + + LV+ + + D + +R + L V Y S+ + EL+ +LC D+ P+VR A +L + + ++ +K ++I +L SD Q VR V+ + + + + + ++ P L + +ED + R VA +E QK + + K+ L L++D E + R A ++KEFC + C V++ +LP ++E ++ + VK+ L ++ + P +++++ L+ L+ L D + + + + + +I +L ++LP++ +L D WR+R ++ + L+ + + L ++WL D V+ IR+ + + +F + + P + D NY R F + + + ++ + L+ + +++DQV NV+ + +S++ + L+ N L + V + + DIDV+ F+ AL
Sbjct: 21 IDELRNEDVQLRLNSIKKLSTIALALGVERTRSELIPFLTDTIY-----DEDEVLLALAEQLGSFTTLVGGPEYVHCLLPPLESLATVEETVVRDKAV-ESLRAISAEHSPADLEAHFVPLVKRLASGDWF-TSRTSACGLFSVAYPRVSNAVKAELRQHFRNLC--GDDTPMVRRAAASKLGEFAKVLEIDYIKNDVIPMFNNLASDEQDSVRLLAVEACVNIASLLPAEDLEAMVMPTLRQAAEDKSWRVRYMVADKFNEIQKAVGSEITKTDLVPAFQNLLKDCEAEVRAAAAHKVKEFCENLPSDCQESVIMSNILPCVKELVS-DANQHVKSALASVIMGLSPILGKDNTIEHLLPLFLAQLKDECPEVRLNIISNLDCVNEVIGIRQLSQSLLPAIVELAEDTKWRVRLAIIEYMPLLAGQLGVEFFDEKLNSLCMAWLVDHVYAIREAATNNLKKLVEKFGKEWAQSTI-IPKVLAMSNDHNYLHRMTTLFCVNVLAEVCGQDITAKLMLPTVLR---------MAQDQVANVRFNVAKSLQKIGPILETNTLQSE-VKPVLEKLGGDQDIDVKYFAQEAL 587
BLAST of Serine/threonine-protein phosphatase 2A regulatory subunit A vs. Ensembl Yeast
Match: TPD3 (Regulatory subunit A of the heterotrimeric PP2A complex; the heterotrimeric protein phosphatase 2A (PP2A) complex also contains regulatory subunit Cdc55p and either catalytic subunit Pph21p or Pph22p; required for cell morphogenesis and transcription by RNA polymerase III [Source:SGD;Acc:S000000014]) HSP 1 Score: 105.145 bits (261), Expect = 6.100e-24 Identity = 121/474 (25.53%), Postives = 216/474 (45.57%), Query Frame = 1
Query: 184 DTAEKLRAFHLLPTVALTLKSENTRTMLIPILETLITTAVDNGDDEALMVIAQKLGDFVPLVGGGNYAGCLLQLLARXXXXXXXXXXXQAACDSLIKIIPTLDSNVVDTNCLQLVRNVFAEDLYCAARKAGVRLIPVCYKIASSESQTELKNRL-LHLCMAEDEIPLVRAGAVEQ---LTDLSIVAGSVLKPE----MIRTLTSLVSDNQRVVRAACVKPLLELGKNVDTNEFDTILFPLLD---KLSEDSNRDTRRGVA----SLISEFQKIAQKFDKSLHNLLIKLMEDNEIDARKIVASQLKEFCAACSH-QVLIDFVLPKIREHLNLEREDRVKAELVKSVVTMIPSFKRE----DSLPLVQHVLSFLNDSNLQTKQYVFEHFQGLIGLISPSELQLTILPSLFKLFADKNWRIRSGVVASLMLIIPIVDEACCRDTLLPTTLSWLKDPVWNIRQGTCELIGSITGRFPS 1545
D A ++ A L T+AL L E TR LIP L T + +DE V+A++LG FVP +GG YA LL +L I+ EE +V + A DSL + L + ++ + L+ ++ D + + A V +I + KN L L+L +A+D+ P+V+ + L DL + E + +++DNQ V+ V L+ + K + ++ LL+ KL D R A L S+F Q + L + L EDNE D R+ VA Q+ F + ++++ +LP + ++L+++ + V++ L + ++ ++ + LP+ +L+ L D + + + + +I L ++LP++ +L D NWR+R ++ + ++ + L LSWL D V++IR+ + +T F S
Sbjct: 50 DIANRVEAMKKLDTIALALGPERTRNELIPFL----TEVAQDDEDEVFAVLAEQLGKFVPYIGGPQYATILLPVL-EILASAEETLVREKAVDSLNNVAQELSQEQLFSDFVPLIEHLATADWFSSKVSACGLFKSVIVRIKDDSLR---KNILALYLQLAQDDTPMVKRAVGKNLPILIDLLTQNLGLSTDEDWDYISNIFQKIINDNQDSVKFLAVDCLISILKFFNAKGDESHTQDLLNSAVKLIGDEAWRVRYMAADRFSDLASQFSS-NQAYIDELVQPFLNLCEDNEGDVREAVAKQVSGFAKFLNDPSIILNKILPAV-QNLSMDESETVRSALASKITNIVLLLNKDQVINNFLPI---LLNMLRDEFPDVRLNIIASLKVVNDVIGIELLSDSLLPAITELAKDVNWRVRMAIIEYIPILAEQLGMQFFDQQLSDLCLSWLWDTVYSIREAAVNNLKRLTEIFGS 510
BLAST of Serine/threonine-protein phosphatase 2A regulatory subunit A vs. Ensembl Yeast
Match: GCN1 (Positive regulator of the Gcn2p kinase activity; forms a complex with Gcn20p; proposed to stimulate Gcn2p activation by an uncharged tRNA [Source:SGD;Acc:S000003163]) HSP 1 Score: 47.7506 bits (112), Expect = 7.351e-6 Identity = 75/330 (22.73%), Postives = 135/330 (40.91%), Query Frame = 1
Query: 184 DTAEKLRAFHLLPTVALTLKSENTRTMLIPILETLITTAVDNGDDEALMVIAQKLGDFVPLVGGGNYAGCLLQLLARXXXXXXXXXXXQAACDSLIKIIPTLDSNVVD---TNCLQLVRNVFAEDLYCAARKAGVRLIPVCYKIASSESQTELKNRLLHLCMAEDEIPLVRAGAVEQLTDLSIVAGSVLKPEMIRTLTSLVSDNQRVVRAACVKPLLELGKNVDTNEFDTILFPLLDKLSEDSNRDTRRGVASLISEFQKIAQKFDKSLHNLL---IKLMEDNEIDARKIVASQLKEFCAACSHQVLIDF--VLPKIREH--LNLEREDR 1143
DT+ +RA + AL + ++P L +I T + + + + AQ LGD V V GGN LL L + Q C +L ++I + + + + + ++R D R+A V + + E+ LLH+ + D G E ++ S V+ P +I TL + D RA+ + L E+ + I+ L+D + S ++ +G L + ++ D+ LH LL + L++ + I+ R V +L F + ++DF +P H L+L+ ED+
Sbjct: 1840 DTSGIVRATTVDIWKALVPNTPRAVKEILPTLTGMIVTHLASSSNVLRNIAAQTLGDLVRRV-GGNALSQLLPSLEESLIETSNSDSRQGVCIALYELIESASTETISQFQSTIVNIIRTALI-DESATVREAAALSFDVFQDVVGKTAVDEVLPYLLHMLESSDNSDFALLGLQEIMSKKS----DVIFPILIPTLLAPPID---AFRASALGSLAEVAGSALYKRLSIIINALVDAIIGTSEDESTKGALELALDRVFLSVNDDEGLHPLLQQIMSLLKSDNIEKRIAVLERLPNFF----DKTVLDFDVYIPNFVSHAILSLDDEDQ 2156
BLAST of Serine/threonine-protein phosphatase 2A regulatory subunit A vs. Ensembl Nematostella
Match: EDO33664 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SRI7]) HSP 1 Score: 144.436 bits (363), Expect = 1.900e-36 Identity = 148/591 (25.04%), Postives = 278/591 (47.04%), Query Frame = 1
Query: 166 IDE-DNIDTAEKLRAFHLLPTVALTLKSENTRTMLIPILETLITTAVDNGDDEALMVIAQKLGDFVPLVGGGNYAGCLLQLLARXXXXXXXXXXXQAACDSLIKIIPTLDSNVVDTNCLQLVRNVFAEDLYCAARKAGVRLIPVCYKIASSESQTELKNRLLHLCMAEDEIPLVRAGAVEQLTDLS-IVAGSVLKPEMIRTLTSLVSDNQRVVRAACVKPLLELGKNVDTNEFDTILFPLLDKLSEDSNRDTRRGVASLISEFQK-IAQKFDKS-LHNLLIKLMEDNEIDARKIVASQLKEFCAACS----HQVLIDFVLPKIREHLNLEREDRVKAELVKSVVTMIPSFKREDSLP-LVQHVLSFLNDSNLQTKQYVFEHFQGLIGLISPSELQLTILPSLFKLFADKNWRIRSGVVASLMLIIPIVDEACCRDTLLPTTLSWLKDPVWNIRQGTCELIGSITGRF-PSLLTEKLVKAPIFKELFEDVNYHLRQCWCFLIEAICKSQPKESKSDLLTSFLTNHVNELLLAMISKDQVFNVQISAIRSIKLLSSYLDKNFLHKQXXXXXXXXXXXXXDIDVRDFSDAALKG 1908
IDE N D +L + L T+AL L E T+T LIP L I +DE L+ +A +LG F PLVGG +A CLL L + E +V +A +SL I L + ++ + + L++ + D + R + L VCY ++ + EL+ + +LC D+ P+VR A +L + + ++ +K E++ T+L SD Q VR V+ ++ + + + D+IL P + + D + R VA I+E QK + + K+ L L++D E + R A ++KEF + S VL+ +LP ++E L ++ VK+ L ++ + P +++++ L+ L+ L D + + + + + +I +L ++LP++ +L D WR+R ++ + L+ + + L +SWL D V +IR+ + + +F P ++++ P + + NY R + + E+ S L+ + N ++ D V NV+ + ++++ + LD + + Q + ++ D+DV+ F+ AL
Sbjct: 17 IDELRNEDVQLRLNSIKKLSTIALALGVERTKTELIPFLTDTIY-----DEDEVLLALASQLGTFTPLVGGPEHAHCLLPPLENLATVEETVVRDKAV-ESLRLISADLSTQDLENHFVPLLKRLSQGDWF-TLRTSACGLFSVCYPRINANMKAELRVQFRNLC--NDDTPMVRRAAAGKLGEFAKVMELEFVKSELVPLFTNLSSDEQDSVRLLAVENCPQIAQVLPHEDKDSILMPTVKSAAYDKSWRVRYMVADKITELQKAVGPEITKTELVPAFQVLLKDCEAEVRAAAAGKVKEFSESLSSDIRESVLMTNILPCVKE-LVIDPNQHVKSALASVIMGLSPLLGKDNTIEHLLPLFLTMLKDEFPEVRLNIISNLDCVNQVIGVHQLSQSLLPAIVELAEDTKWRVRLAIIEYMPLLAGQLGVDFFDEKLNTLCMSWLVDHVCSIREAAAINLKKLVEKFGPEWAQQQVI--PKVLAMAREPNYLHRLTTLNSVSVLADVCGPENISKLMLPVVLN---------LATDNVANVRFNVAKTLQKIGPLLDASTIQAQ-IKPCLDKLNADADVDVKYFAQEALTA 585
BLAST of Serine/threonine-protein phosphatase 2A regulatory subunit A vs. Ensembl Medaka
Match: ENSORLT00000009340.2 (serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform [Source:NCBI gene;Acc:101167061]) HSP 1 Score: 160.614 bits (405), Expect = 2.282e-41 Identity = 158/595 (26.55%), Postives = 286/595 (48.07%), Query Frame = 1
Query: 160 VNIDE-DNIDTAEKLRAFHLLPTVALTLKSENTRTMLIPILETLITTAVDNGDDEALMVIAQKLGDFVPLVGGGNYAGCLLQLLARXXXXXXXXXXXQAACDSLIKIIPTLDSNVVDTNCLQLVRNVFAEDLYCAARKAGVRLIPVCYKIASSESQTELKNRLLHLCMAEDEIPLVRAGAVEQLTDLSIVAGSVLKPEMIRT-----LTSLVSDNQRVVRAACVKPLLELGKNVDTNEFDTILFPLLDKLSEDSNRDTRRGVASLISEFQK-IAQKFDKS-LHNLLIKLMEDNEIDARKIVASQLKEFCAACS----HQVLIDFVLPKIREHLNLEREDRVKAELVKSVVTMIPSFKREDSLP-LVQHVLSFLNDSNLQTKQYVFEHFQGLIGLISPSELQLTILPSLFKLFADKNWRIRSGVVASLMLIIPIVDEACCRDTLLPTTLSWLKDPVWNIRQ-GTCELIGSITGRFPSLLTEKLVKAPIFKELFEDVNYHLRQCWCFLIEAICKSQPKESKSDLLTSFLTNHVNELLLAMISKDQVFNVQISAIRSIKLLSSYLDKNFLHKQXXXXXXXXXXXXXDIDVRDFSDAAL 1902
V IDE N D +L + L T+AL L E TRT L+P L I +DE L+ +A++LG+F LVGG Y CLL L + E +V +A +SL KI ++ + LV+ + + D + +R + L VCY SS + E++ LC D+ P+VR A +L + + VL+PE +++ T+L SD Q VR V+ + + + + +T++ P L + +ED + R VA SE QK + + K+ L L++D E + R A+++KEFC Q+++ +LP ++E ++ + VK+ L ++ + +++++ L+ L+ L D + + + + + +I +L ++LP++ +L D WR+R ++ + L+ + + L ++WL D V+ IR+ TC L+ + +F + + + P + D NY R F I A+ ++ +E T + ++L M S DQV NV+ + +S++ + LD N L + V + + ++ D+DV+ F+ A+
Sbjct: 15 VLIDELRNEDVQLRLNSIKKLSTIALALGVERTRTELLPFLTDTIY-----DEDEVLLALAEQLGNFTMLVGGPEYVHCLLPPLESLATVEETVVRDKAV-ESLRKISQEHSPVDLEVHFEPLVKRLASGDWF-TSRTSACGLFSVCYPRVSSTVKAEIRQHFRTLC--SDDTPMVRRAAASKLGEFA----KVLEPEYVKSDIISLFTALASDEQDSVRLLAVEACVSIATLLPQEDLETLVMPTLRQAAEDKSWRVRYMVADKFSELQKAVGSEITKNDLVPAFQNLLKDCEAEVRAAAANKVKEFCENLPEDNREQIIMTHILPCVKELVS-DTNQHVKSALASVIMGLSTILGKDNTIEHLLPLFLAQLKDECPEVRLNIISNLDCVNEVIGIRQLSQSLLPAIVELAEDAKWRVRLAIIEYMPLLAGQLGVEFFDEKLNTLCMAWLIDHVYAIREAATCNLM-KLVEKFGAEWAQNTI-VPKVLGMANDPNYLHRMTTLFCINALSEACGQE--------ITTKQMLPVVLKM-SNDQVANVRFNVAKSLQKIGPVLDSNALQTE-VKPVLEKLATDSDMDVKYFAQEAI 583
BLAST of Serine/threonine-protein phosphatase 2A regulatory subunit A vs. Planmine SMEST
Match: SMESG000014991.1 (SMESG000014991.1) HSP 1 Score: 1196.42 bits (3094), Expect = 0.000e+0 Identity = 617/617 (100.00%), Postives = 617/617 (100.00%), Query Frame = 1
Query: 55 MASNEFVENIIQTLKGFCVSYNNNSAIDGVEQKKIVNIDEDNIDTAEKLRAFHLLPTVALTLKSENTRTMLIPILETLITTAVDNGDDEALMVIAQKLGDFVPLVGGGNYAGCLLQLLARXXXXXXXXXXXQAACDSLIKIIPTLDSNVVDTNCLQLVRNVFAEDLYCAARKAGVRLIPVCYKIASSESQTELKNRLLHLCMAEDEIPLVRAGAVEQLTDLSIVAGSVLKPEMIRTLTSLVSDNQRVVRAACVKPLLELGKNVDTNEFDTILFPLLDKLSEDSNRDTRRGVASLISEFQKIAQKFDKSLHNLLIKLMEDNEIDARKIVASQLKEFCAACSHQVLIDFVLPKIREHLNLEREDRVKAELVKSVVTMIPSFKREDSLPLVQHVLSFLNDSNLQTKQYVFEHFQGLIGLISPSELQLTILPSLFKLFADKNWRIRSGVVASLMLIIPIVDEACCRDTLLPTTLSWLKDPVWNIRQGTCELIGSITGRFPSLLTEKLVKAPIFKELFEDVNYHLRQCWCFLIEAICKSQPKESKSDLLTSFLTNHVNELLLAMISKDQVFNVQISAIRSIKLLSSYLDKNFLHKQXXXXXXXXXXXXXDIDVRDFSDAALK 1905
MASNEFVENIIQTLKGFCVSYNNNSAIDGVEQKKIVNIDEDNIDTAEKLRAFHLLPTVALTLKSENTRTMLIPILETLITTAVDNGDDEALMVIAQKLGDFVPLVGGGNYAGCLLQLLARIICCVEEIVVVQAACDSLIKIIPTLDSNVVDTNCLQLVRNVFAEDLYCAARKAGVRLIPVCYKIASSESQTELKNRLLHLCMAEDEIPLVRAGAVEQLTDLSIVAGSVLKPEMIRTLTSLVSDNQRVVRAACVKPLLELGKNVDTNEFDTILFPLLDKLSEDSNRDTRRGVASLISEFQKIAQKFDKSLHNLLIKLMEDNEIDARKIVASQLKEFCAACSHQVLIDFVLPKIREHLNLEREDRVKAELVKSVVTMIPSFKREDSLPLVQHVLSFLNDSNLQTKQYVFEHFQGLIGLISPSELQLTILPSLFKLFADKNWRIRSGVVASLMLIIPIVDEACCRDTLLPTTLSWLKDPVWNIRQGTCELIGSITGRFPSLLTEKLVKAPIFKELFEDVNYHLRQCWCFLIEAICKSQPKESKSDLLTSFLTNHVNELLLAMISKDQVFNVQISAIRSIKLLSSYLDKNFLHKQLVPVLKKLSSSSLDIDVRDFSDAALK
Sbjct: 1 MASNEFVENIIQTLKGFCVSYNNNSAIDGVEQKKIVNIDEDNIDTAEKLRAFHLLPTVALTLKSENTRTMLIPILETLITTAVDNGDDEALMVIAQKLGDFVPLVGGGNYAGCLLQLLARIICCVEEIVVVQAACDSLIKIIPTLDSNVVDTNCLQLVRNVFAEDLYCAARKAGVRLIPVCYKIASSESQTELKNRLLHLCMAEDEIPLVRAGAVEQLTDLSIVAGSVLKPEMIRTLTSLVSDNQRVVRAACVKPLLELGKNVDTNEFDTILFPLLDKLSEDSNRDTRRGVASLISEFQKIAQKFDKSLHNLLIKLMEDNEIDARKIVASQLKEFCAACSHQVLIDFVLPKIREHLNLEREDRVKAELVKSVVTMIPSFKREDSLPLVQHVLSFLNDSNLQTKQYVFEHFQGLIGLISPSELQLTILPSLFKLFADKNWRIRSGVVASLMLIIPIVDEACCRDTLLPTTLSWLKDPVWNIRQGTCELIGSITGRFPSLLTEKLVKAPIFKELFEDVNYHLRQCWCFLIEAICKSQPKESKSDLLTSFLTNHVNELLLAMISKDQVFNVQISAIRSIKLLSSYLDKNFLHKQLVPVLKKLSSSSLDIDVRDFSDAALK 617
BLAST of Serine/threonine-protein phosphatase 2A regulatory subunit A vs. Planmine SMEST
Match: SMESG000034505.1 (SMESG000034505.1) HSP 1 Score: 144.05 bits (362), Expect = 5.594e-36 Identity = 159/596 (26.68%), Postives = 271/596 (45.47%), Query Frame = 1
Query: 160 VNIDE-DNIDTAEKLRAFHLLPTVALTLKSENTRTMLIPILETLITTAVDNGDDEALMVIAQKLGDFVPLVGGGNYAGCLLQLLARXXXXXXXXXXXQAACDSLIKIIPTLDSNVVDTNCLQLVRNVFAEDLYCAARKAGVRLIPVCYKIASSESQTELKNRLLHLCMAEDEIPLVRAGAVEQLTD-LSIVAGSVLKPEMIRTLTSLVSDNQRVVRAACVKPLLELGKNVDTNEFDTILFPLLDKLSEDSNRDTRRGVASLISEFQK--IAQKFDKSLHNLLIKLMEDNEIDARKIVASQLKEFCAA----CSHQVLIDFVLPKIREHLNLEREDRVKAELVKSVVTMIPSFKR----EDSLPLVQHVLSFLNDSNLQTKQYVFEHFQGLIGLISPSELQLTILPSLFKLFADKNWRIRSGVVASLMLIIPIVD-EACCRDTLLPTTLSWLKDPVWNIRQGTCELIGSITGRFPSLLTEKLVKAPIFKELFEDVNYHLRQCWCFLIEAICKSQPKESKSDLLTSFLTNHVNELLLAMISKDQVFNVQISAIRSIKLLSSYLDKNFLHKQXXXXXXXXXXXXXDIDVRDFSDAALKG 1908
V IDE N D +L + LPTVAL L E TR LIP L + +DE L+ +A++LG FVPLVGG +A CLL L + VEE VV A DSL + + ++ + + L+R + + + + +R + L CY S+ +TEL R L +A D+ P+VR A +L + ++++ +K +++ L +V D Q VR + + K + ++ + + L+ +ED + R VA I E +K IA L ++ L++D+E + + +LK+FC V + LP ++E +N + +VK L ++ + P + E LP+ L+ L D N + + + L +I + ++P++ +L D WR+R ++ + L+ ++ + D L LSWL DPV+ +R+ + ++ +F S ++ V I ++ NY R IC + L + + H +L ++S D V NV+ ++ L LD N + V + D DV FS A+KG
Sbjct: 16 VLIDELRNDDVQTRLISIKKLPTVALALGMERTRNELIPFLTDTVY-----DEDEVLLALAEQLGSFVPLVGGLEFAYCLL-LPLETLATVEETVVRDKAVDSLRIVAASHSPQDLEKHFVPLIRRLSSGEWF-TSRTSACGLFSCCYARLSTNLKTEL--RRLFRQLATDDTPMVRRAAASRLGEFVTVMDLEDVKSDLLLLLPVVVQDEQDSVRLLGIGACVSFCKILPKDDIKSSIISLIRGGAEDKSWRVRHAVAENILEIEKLSIADVTQSGLVDIYTVLLKDSEAEVKSAAVGKLKDFCETLLKDSKESVTVKSFLPIVKEMIN-DPNIQVKISLAGVLMGLSPIIGKVNTTEHLLPI---FLTQLKDENAEVRLNLISKLDCLSEVIGAKQASQNLIPTIIELADDAKWRVRLALMQHIPLLAGLLGPQVFSEDKLTTLCLSWLADPVYAVREAAANNLKTLVDKFGSNWCQQYVLTKIV-DMSRSHNYLHRM--------ICLHSIQNLSEVLASDMIQKHFLPILNTLVS-DPVPNVRFKTAQTYAKLCKKLDSN--SQVTVKKALDKMKADSDNDVVYFSQQAIKG 586
BLAST of Serine/threonine-protein phosphatase 2A regulatory subunit A vs. Planmine SMEST
Match: SMESG000072818.1 (SMESG000072818.1) HSP 1 Score: 139.043 bits (349), Expect = 2.958e-34 Identity = 158/600 (26.33%), Postives = 277/600 (46.17%), Query Frame = 1
Query: 166 IDE-DNIDTAEKLRAFHLLPTVALTLKSENTRTMLIPILETLITTAVDNGDDEALMVIAQKLGDFVPLVGGGNYAGCLLQLLARXXXXXXXXXXXQA--ACDSLIKIIPTLDSNVVDTNCLQLVRNVFAEDLYCAARKAGVRLIPVCYKIASSESQTELKNRLLHLCMAEDEIPLVRAGAVEQLTDL-SIVAGSVLKPEMIRTLTSLVSDNQRVVRAACVKPLLELGKNVDTNEFDTILFPLLDKLSEDSNRDTRRGVASLISEFQK-IAQKFD-KSLHNLLIKLMEDNEIDARKIVASQLKEFCAACS----HQVLIDFVLPKIREHLNLEREDRVKAELVKSVVTMIPSFKREDSLP-LVQHVLSFLNDSNLQTKQYVFEHFQGLIGLISPSELQLTILPSLFKLFADKNWRIRSGVVASLMLI-----IPIVDEACCRDTLLPTTLSWLKDPVWNIRQGTCELIGSITGRFPSLLTEKLVKAPIFKELFEDVNYHLRQCWCFL----IEAICKSQPKESKSDLLTSFLTNHVNELLLAMISKDQVFNVQISAIRSIKLLSSYLDKNFLHKQXXXXXXXXXXXXXDIDVRDFSDAALK 1905
IDE N D ++ + L T+AL L +E TR+ LIP L + +DE L+ +A++L DF PLVGG Y CLL L + E IV +A L K T D ++ + +V+ + + + + +R + L V Y S E +TEL LC+ D+ P+VR A ++L DL S++ ++ EM+ L + D Q VR + + + + T + P + SED + R +A I + Q+ I K + L N+ KL+ D+E + + S++KEFC A V+++ + P ++ L E VK L V+ + P +++ + L+ L L D N + V + + + I +L + +LP++ +L DK WR+R ++ + L+ +PI ++ D + ++ L D V+ +R+ I ++ +F +K V P EL D NY L + C L I +C ++ + +H+ +L+ M S D+V NV+ + + L S +D + + + ++ LD+DV F+ A++
Sbjct: 16 IDELRNDDIQIRINSIKKLATIALVLGAERTRSELIPFLTDTVY-----DEDEVLLALAEQLKDFTPLVGGNEYVYCLLPPLETLATVEETIVRDKAVETLQHLEKFHSTQD---LEKYYVPMVKRLSSGEWF-TSRTSASGLYSVVYPRVSIEIKTELSQVYRQLCI--DDTPMVRRAAAQRLGDLVSVMNVENVRNEMLPILNVVSQDEQDSVRLLSMGCGVSFSSVLPAEDIFTHIIPTIKAASEDKSWRVRCMLAENIVKLQQNIGAKMTMEHLVNVYEKLLNDSEAEVKSNAVSKMKEFCTALPADKRESVIMNQIFPAVKA-LVQEANMHVKTTLAGQVMGLAPLLGKQNVIDHLIPIFLVQLRDENPDVRLNVICNLECVNNAIGVQQLSVNLLPAIVELSEDKKWRVRLAIIEYVPLLAGQLGLPIFND----DEITSLCMNRLLDNVYTVREAAVNSIKALVAKFGIDWAKKNV-LPKMIELSTDTNY-LHRMICLLSILRIGEVCDAE-----------VIRSHLLSILVQM-SNDKVPNVRFKTAQILAKLGSKMDNDTI-QSIINGTLNRLKDDLDVDVAHFALQAMR 584
BLAST of Serine/threonine-protein phosphatase 2A regulatory subunit A vs. Planmine SMEST
Match: SMESG000019633.1 (SMESG000019633.1) HSP 1 Score: 139.043 bits (349), Expect = 3.078e-34 Identity = 135/519 (26.01%), Postives = 241/519 (46.44%), Query Frame = 1
Query: 178 NIDTAEKLRAFHLLPTVALTLKSENTRTMLIPILETLITTAVDNGDDEALMVIAQKLGDFVPLVGGGNYAGCLLQLLARXXXXXXXXXXXQAACDSLIKIIPTLDSNVVDTNCLQLVRNVFAEDLYCAARKAGVRLIPVCYKIASSESQTELKNRLLHLCMAEDEIPLVRAGAVEQLTDLSIVAGSVLKPEMIRT-----LTSLVSD-NQRVVRAACVKPLLELGKNVDTN---------------EFDTILFPLLDKLSEDSNRDTRRGVASLISEFQ----KIAQKFDKSLHNLLIKLMEDNEIDARKIVASQLKEFCAACS----HQVLIDFVLPKIREHLNLEREDRVKAELVKSVVTMIPSFKREDSLPLVQHVLSF----LNDSNLQTKQYVFEHFQGLIGLISPSELQLTILPSLFKLFADKNWRIRSGVVASLMLIIPIVDEACCRDTLLPTTLSWLKDPVWNIRQGTCELIGSITGRFPSLLTEKLVKAPIFKELFEDVNYHLR----QC 1623
N D +L + L T++L L +E TR+ LIP L I +DE L+ +A++LG+F+ VGG Y LL L + E IV +A +SL KI P S ++ + L+ N A+ + +R + L+ Y S+ ++N LC +D+ P+VR A +L ++ SV++P ++RT ++ D + VR V+ ++L + + E + + P L K + D + R VA I E Q I + K L + I L++D++ + R + AS++K F + S Q++ + ++P ++E L ++ VK+ L SV+ + P ++D+ + H+L L D N + + + + + + ++ +L + +LP++ +L AD WR+R ++ + L+ + D L LSWL D V+ IR+ + +T F E ++ P +L +D NY R QC
Sbjct: 22 NDDVQLRLNSIKRLTTISLALGAERTRSELIPFLTETIY-----DEDEVLLALAEQLGNFISYVGGPEYVYTLLPPLENLAIVEESIVRDKAV-ESLRKIAPDHSSLHLEEFFIPLI-NKLAKGEWFTSRTSACGLLSSVYARIGDLSKANMRNLYKTLC--KDDTPMVRRAAAARLGEM----ASVMEPNLVRTDLVPLFAQMIQDEDHDSVRLLAVEATVQLCGAIKMSCSMLEMDNRSLSYEEELERFIVPQLLKAATDKSWRVRYMVADKIVEIQCSFGIILSR--KHLLTVFINLLKDSQAEVRSVSASKIKSFTSELSVENRDQIIKEQIIPVVKE-LTVDTNCHVKSSLATSVMGLAPFIGKQDT---ITHLLPIFIQQLKDENSEVRVNIISNIEQVHNVLGYEQLSMNLLPTIVELSADNKWRVRLAIIENFPLLASQLGRKFFDDQLKTVCLSWLVDHVYAIREAAVNNLTRLTEIFGVEWAESMI-VPRMVQLSKDTNYLHRMICLQC 520 The following BLAST results are available for this feature:
BLAST of Serine/threonine-protein phosphatase 2A regulatory subunit A vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Serine/threonine-protein phosphatase 2A regulatory subunit A vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 2
BLAST of Serine/threonine-protein phosphatase 2A regulatory subunit A vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Serine/threonine-protein phosphatase 2A regulatory subunit A vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 2
BLAST of Serine/threonine-protein phosphatase 2A regulatory subunit A vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Serine/threonine-protein phosphatase 2A regulatory subunit A vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Serine/threonine-protein phosphatase 2A regulatory subunit A vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Serine/threonine-protein phosphatase 2A regulatory subunit A vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Serine/threonine-protein phosphatase 2A regulatory subunit A vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 2
BLAST of Serine/threonine-protein phosphatase 2A regulatory subunit A vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 1
BLAST of Serine/threonine-protein phosphatase 2A regulatory subunit A vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 2
BLAST of Serine/threonine-protein phosphatase 2A regulatory subunit A vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 1
BLAST of Serine/threonine-protein phosphatase 2A regulatory subunit A vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 1
BLAST of Serine/threonine-protein phosphatase 2A regulatory subunit A vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 4
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30008675 ID=SMED30008675|Name=Serine/threonine-protein phosphatase 2A regulatory subunit A|organism=Schmidtea mediterranea sexual|type=transcript|length=2135bpback to top protein sequence of SMED30008675-orf-1 >SMED30008675-orf-1 ID=SMED30008675-orf-1|Name=SMED30008675-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=634bp MASNEFVENIIQTLKGFCVSYNNNSAIDGVEQKKIVNIDEDNIDTAEKLRback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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