Phosphodiesterase
|
Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30008671 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 14
Homology
BLAST of Phosphodiesterase vs. Ensembl Human
Match: PDE2A (phosphodiesterase 2A [Source:HGNC Symbol;Acc:HGNC:8777]) HSP 1 Score: 721.465 bits (1861), Expect = 0.000e+0 Identity = 369/722 (51.11%), Postives = 502/722 (69.53%), Query Frame = 1
Query: 595 SNQINQILELCGSLFDQDAGKLQKKVLSYLIQNTSAETGFLLLVCMDTVELLCQVIGQVIQEDPINFDAEENGIFDKVLKSKTGINLGCLTEAQLREISEIMNASKQETKIQNALCVPVRHQGTNDVIAIVCLINKSGPAQFTNYDEQVINECFKYTTSVLFTTIAYQNERRLKLQTEKMLVVAKNIFSRMDNLNELLLMIMQEARNLTQAERCSVFLVDEDSNELVAKVFDGLPTSSDKNERLRLQDGTEIQQPVEIRFPKAQGIAGHVATTGEMLNIKKAYDHPLFYRGVDDETGFKTKNILCFPIQDDCGKTVGVAQLCNKIKGHFFTKMDEEIAKAFSIYCCISITHSLMYKKVEDAQHRSRLANELMMYHMQIPEDDIAWLSTFSIPPVSIFLSDFESFNSIPRNVKDRDTLMACISMFDGIGLISRWRINRRTLTKFIFMVKRNYRDPPYHNWMHAFSVAHFIFICIKNLPLDKQLTELELFALFVASLCHDIDHRGTNNSFQVQSNSILAALYSSEGSVLERHHFSQTVCILNTEGCNVFESLPQKEYXXXXXXXXXXXXXXXXXHHLQIFSKIEKMAQQGYDNLDSENHNLLLCLLMTSADLSDQTKNWRNTRSVAELIYKEFFRQGDLEKAIGNQPAEQMDRERAVVPNLQIAFLDGIVSPLYRVLSLLHPQTDCINHTIERTRENWSKISQKVASHEIKGNSEEIFRNKLVE 2760
+++ +IL+LCG L+D DA LQ KVL YL Q T A LLLV D ++L C+VIG + + ++F G +V++ K I L LT ++++ ++ ++Q LCVPV + T+ V+A+ C NK FT+ DE VI CF YT++VL +T+A+Q E++LK + + +L VAKN+F+ +D+++ LL I+ EARNL+ AE CSVFL+D+ NELVAKVFDG G + EIR P QGIAGHVATTG++LNI AY HPLFYRGVDD TGF+T+NILCFPI+++ + +GVA+L NKI G +F+K DE++A AFSIYC ISI HSL+YKKV +AQ+RS LANE+MMYHM++ +D+ L I PV+ S+F SF PR++ + DT MA +SM + I+ ++I+ TL +F MVK+ YRDPPYHNWMHAFSV+HF ++ KNL L L ++E+FALF++ +CHD+DHRGTNNSFQV S S+LAALYSSEGSV+ERHHF+Q + ILNT GCN+F+ +K+Y R LDL+RDIILATDLAHHL+IF ++KMA+ GYD + ++H LLLCLLMTS DLSDQTK W+ TR +AELIYKEFF QGDLEKA+GN+P E MDRE+A +P LQI+F++ I P+Y++L L P+ + + RE+W+K+S K + N+ F ++ E
Sbjct: 203 TDRDRKILQLCGELYDLDASSLQLKVLQYLQQETRASRCCLLLVSEDNLQLSCKVIGDKVLGEEVSFPL--TGCLGQVVEDKKSIQLKDLTSEDVQQLQSMLGC-----ELQAMLCVPVISRATDQVVALACAFNKLEGDLFTDEDEHVIQHCFHYTSTVLTSTLAFQKEQKLKCECQALLQVAKNLFTHLDDVSVLLQEIITEARNLSNAEICSVFLLDQ--NELVAKVFDG---------------GVVDDESYEIRIPADQGIAGHVATTGQILNIPDAYAHPLFYRGVDDSTGFRTRNILCFPIKNENQEVIGVAELVNKINGPWFSKFDEDLATAFSIYCGISIAHSLLYKKVNEAQYRSHLANEMMMYHMKVSDDEYTKLLHDGIQPVAAIDSNFASFTYTPRSLPEDDTSMAILSMLQDMNFINNYKIDCPTLARFCLMVKKGYRDPPYHNWMHAFSVSHFCYLLYKNLELTNYLEDIEIFALFISCMCHDLDHRGTNNSFQVASKSVLAALYSSEGSVMERHHFAQAIAILNTHGCNIFDHFSRKDYQRMLDLMRDIILATDLAHHLRIFKDLQKMAEVGYDRNNKQHHRLLLCLLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEKAMGNRPMEMMDREKAYIPELQISFMEHIAMPIYKLLQDLFPKAAELYERVASNREHWTKVSHKFTIRGLPSNNSLDFLDEEYE 900
BLAST of Phosphodiesterase vs. Ensembl Human
Match: PDE2A (phosphodiesterase 2A [Source:HGNC Symbol;Acc:HGNC:8777]) HSP 1 Score: 721.079 bits (1860), Expect = 0.000e+0 Identity = 367/712 (51.54%), Postives = 498/712 (69.94%), Query Frame = 1
Query: 595 SNQINQILELCGSLFDQDAGKLQKKVLSYLIQNTSAETGFLLLVCMDTVELLCQVIGQVIQEDPINFDAEENGIFDKVLKSKTGINLGCLTEAQLREISEIMNASKQETKIQNALCVPVRHQGTNDVIAIVCLINKSGPAQFTNYDEQVINECFKYTTSVLFTTIAYQNERRLKLQTEKMLVVAKNIFSRMDNLNELLLMIMQEARNLTQAERCSVFLVDEDSNELVAKVFDGLPTSSDKNERLRLQDGTEIQQPVEIRFPKAQGIAGHVATTGEMLNIKKAYDHPLFYRGVDDETGFKTKNILCFPIQDDCGKTVGVAQLCNKIKGHFFTKMDEEIAKAFSIYCCISITHSLMYKKVEDAQHRSRLANELMMYHMQIPEDDIAWLSTFSIPPVSIFLSDFESFNSIPRNVKDRDTLMACISMFDGIGLISRWRINRRTLTKFIFMVKRNYRDPPYHNWMHAFSVAHFIFICIKNLPLDKQLTELELFALFVASLCHDIDHRGTNNSFQVQSNSILAALYSSEGSVLERHHFSQTVCILNTEGCNVFESLPQKEYXXXXXXXXXXXXXXXXXHHLQIFSKIEKMAQQGYDNLDSENHNLLLCLLMTSADLSDQTKNWRNTRSVAELIYKEFFRQGDLEKAIGNQPAEQMDRERAVVPNLQIAFLDGIVSPLYRVLSLLHPQTDCINHTIERTRENWSKISQKVASHEIKGNS 2730
+++ +IL+LCG L+D DA LQ KVL YL Q T A LLLV D ++L C+VIG + + ++F G +V++ K I L LT ++++ ++ ++Q LCVPV + T+ V+A+ C NK FT+ DE VI CF YT++VL +T+A+Q E++LK + + +L VAKN+F+ +D+++ LL I+ EARNL+ AE CSVFL+D+ NELVAKVFDG G + EIR P QGIAGHVATTG++LNI AY HPLFYRGVDD TGF+T+NILCFPI+++ + +GVA+L NKI G +F+K DE++A AFSIYC ISI HSL+YKKV +AQ+RS LANE+MMYHM++ +D+ L I PV+ S+F SF PR++ + DT MA +SM + I+ ++I+ TL +F MVK+ YRDPPYHNWMHAFSV+HF ++ KNL L L ++E+FALF++ +CHD+DHRGTNNSFQV S S+LAALYSSEGSV+ERHHF+Q + ILNT GCN+F+ +K+Y R LDL+RDIILATDLAHHL+IF ++KMA+ GYD + ++H LLLCLLMTS DLSDQTK W+ TR +AELIYKEFF QGDLEKA+GN+P E MDRE+A +P LQI+F++ I P+Y++L L P+ + + RE+W+K+S K + N+
Sbjct: 215 TDRDRKILQLCGELYDLDASSLQLKVLQYLQQETRASRCCLLLVSEDNLQLSCKVIGDKVLGEEVSFPL--TGCLGQVVEDKKSIQLKDLTSEDVQQLQSMLGC-----ELQAMLCVPVISRATDQVVALACAFNKLEGDLFTDEDEHVIQHCFHYTSTVLTSTLAFQKEQKLKCECQALLQVAKNLFTHLDDVSVLLQEIITEARNLSNAEICSVFLLDQ--NELVAKVFDG---------------GVVDDESYEIRIPADQGIAGHVATTGQILNIPDAYAHPLFYRGVDDSTGFRTRNILCFPIKNENQEVIGVAELVNKINGPWFSKFDEDLATAFSIYCGISIAHSLLYKKVNEAQYRSHLANEMMMYHMKVSDDEYTKLLHDGIQPVAAIDSNFASFTYTPRSLPEDDTSMAILSMLQDMNFINNYKIDCPTLARFCLMVKKGYRDPPYHNWMHAFSVSHFCYLLYKNLELTNYLEDIEIFALFISCMCHDLDHRGTNNSFQVASKSVLAALYSSEGSVMERHHFAQAIAILNTHGCNIFDHFSRKDYQRMLDLMRDIILATDLAHHLRIFKDLQKMAEVGYDRNNKQHHRLLLCLLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEKAMGNRPMEMMDREKAYIPELQISFMEHIAMPIYKLLQDLFPKAAELYERVASNREHWTKVSHKFTIRGLPSNN 902
BLAST of Phosphodiesterase vs. Ensembl Human
Match: PDE2A (phosphodiesterase 2A [Source:HGNC Symbol;Acc:HGNC:8777]) HSP 1 Score: 721.079 bits (1860), Expect = 0.000e+0 Identity = 367/712 (51.54%), Postives = 498/712 (69.94%), Query Frame = 1
Query: 595 SNQINQILELCGSLFDQDAGKLQKKVLSYLIQNTSAETGFLLLVCMDTVELLCQVIGQVIQEDPINFDAEENGIFDKVLKSKTGINLGCLTEAQLREISEIMNASKQETKIQNALCVPVRHQGTNDVIAIVCLINKSGPAQFTNYDEQVINECFKYTTSVLFTTIAYQNERRLKLQTEKMLVVAKNIFSRMDNLNELLLMIMQEARNLTQAERCSVFLVDEDSNELVAKVFDGLPTSSDKNERLRLQDGTEIQQPVEIRFPKAQGIAGHVATTGEMLNIKKAYDHPLFYRGVDDETGFKTKNILCFPIQDDCGKTVGVAQLCNKIKGHFFTKMDEEIAKAFSIYCCISITHSLMYKKVEDAQHRSRLANELMMYHMQIPEDDIAWLSTFSIPPVSIFLSDFESFNSIPRNVKDRDTLMACISMFDGIGLISRWRINRRTLTKFIFMVKRNYRDPPYHNWMHAFSVAHFIFICIKNLPLDKQLTELELFALFVASLCHDIDHRGTNNSFQVQSNSILAALYSSEGSVLERHHFSQTVCILNTEGCNVFESLPQKEYXXXXXXXXXXXXXXXXXHHLQIFSKIEKMAQQGYDNLDSENHNLLLCLLMTSADLSDQTKNWRNTRSVAELIYKEFFRQGDLEKAIGNQPAEQMDRERAVVPNLQIAFLDGIVSPLYRVLSLLHPQTDCINHTIERTRENWSKISQKVASHEIKGNS 2730
+++ +IL+LCG L+D DA LQ KVL YL Q T A LLLV D ++L C+VIG + + ++F G +V++ K I L LT ++++ ++ ++Q LCVPV + T+ V+A+ C NK FT+ DE VI CF YT++VL +T+A+Q E++LK + + +L VAKN+F+ +D+++ LL I+ EARNL+ AE CSVFL+D+ NELVAKVFDG G + EIR P QGIAGHVATTG++LNI AY HPLFYRGVDD TGF+T+NILCFPI+++ + +GVA+L NKI G +F+K DE++A AFSIYC ISI HSL+YKKV +AQ+RS LANE+MMYHM++ +D+ L I PV+ S+F SF PR++ + DT MA +SM + I+ ++I+ TL +F MVK+ YRDPPYHNWMHAFSV+HF ++ KNL L L ++E+FALF++ +CHD+DHRGTNNSFQV S S+LAALYSSEGSV+ERHHF+Q + ILNT GCN+F+ +K+Y R LDL+RDIILATDLAHHL+IF ++KMA+ GYD + ++H LLLCLLMTS DLSDQTK W+ TR +AELIYKEFF QGDLEKA+GN+P E MDRE+A +P LQI+F++ I P+Y++L L P+ + + RE+W+K+S K + N+
Sbjct: 217 TDRDRKILQLCGELYDLDASSLQLKVLQYLQQETRASRCCLLLVSEDNLQLSCKVIGDKVLGEEVSFPL--TGCLGQVVEDKKSIQLKDLTSEDVQQLQSMLGC-----ELQAMLCVPVISRATDQVVALACAFNKLEGDLFTDEDEHVIQHCFHYTSTVLTSTLAFQKEQKLKCECQALLQVAKNLFTHLDDVSVLLQEIITEARNLSNAEICSVFLLDQ--NELVAKVFDG---------------GVVDDESYEIRIPADQGIAGHVATTGQILNIPDAYAHPLFYRGVDDSTGFRTRNILCFPIKNENQEVIGVAELVNKINGPWFSKFDEDLATAFSIYCGISIAHSLLYKKVNEAQYRSHLANEMMMYHMKVSDDEYTKLLHDGIQPVAAIDSNFASFTYTPRSLPEDDTSMAILSMLQDMNFINNYKIDCPTLARFCLMVKKGYRDPPYHNWMHAFSVSHFCYLLYKNLELTNYLEDIEIFALFISCMCHDLDHRGTNNSFQVASKSVLAALYSSEGSVMERHHFAQAIAILNTHGCNIFDHFSRKDYQRMLDLMRDIILATDLAHHLRIFKDLQKMAEVGYDRNNKQHHRLLLCLLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEKAMGNRPMEMMDREKAYIPELQISFMEHIAMPIYKLLQDLFPKAAELYERVASNREHWTKVSHKFTIRGLPSNN 904
BLAST of Phosphodiesterase vs. Ensembl Human
Match: PDE2A (phosphodiesterase 2A [Source:HGNC Symbol;Acc:HGNC:8777]) HSP 1 Score: 720.309 bits (1858), Expect = 0.000e+0 Identity = 369/722 (51.11%), Postives = 502/722 (69.53%), Query Frame = 1
Query: 595 SNQINQILELCGSLFDQDAGKLQKKVLSYLIQNTSAETGFLLLVCMDTVELLCQVIGQVIQEDPINFDAEENGIFDKVLKSKTGINLGCLTEAQLREISEIMNASKQETKIQNALCVPVRHQGTNDVIAIVCLINKSGPAQFTNYDEQVINECFKYTTSVLFTTIAYQNERRLKLQTEKMLVVAKNIFSRMDNLNELLLMIMQEARNLTQAERCSVFLVDEDSNELVAKVFDGLPTSSDKNERLRLQDGTEIQQPVEIRFPKAQGIAGHVATTGEMLNIKKAYDHPLFYRGVDDETGFKTKNILCFPIQDDCGKTVGVAQLCNKIKGHFFTKMDEEIAKAFSIYCCISITHSLMYKKVEDAQHRSRLANELMMYHMQIPEDDIAWLSTFSIPPVSIFLSDFESFNSIPRNVKDRDTLMACISMFDGIGLISRWRINRRTLTKFIFMVKRNYRDPPYHNWMHAFSVAHFIFICIKNLPLDKQLTELELFALFVASLCHDIDHRGTNNSFQVQSNSILAALYSSEGSVLERHHFSQTVCILNTEGCNVFESLPQKEYXXXXXXXXXXXXXXXXXHHLQIFSKIEKMAQQGYDNLDSENHNLLLCLLMTSADLSDQTKNWRNTRSVAELIYKEFFRQGDLEKAIGNQPAEQMDRERAVVPNLQIAFLDGIVSPLYRVLSLLHPQTDCINHTIERTRENWSKISQKVASHEIKGNSEEIFRNKLVE 2760
+++ +IL+LCG L+D DA LQ KVL YL Q T A LLLV D ++L C+VIG + + ++F G +V++ K I L LT ++++ ++ ++Q LCVPV + T+ V+A+ C NK FT+ DE VI CF YT++VL +T+A+Q E++LK + + +L VAKN+F+ +D+++ LL I+ EARNL+ AE CSVFL+D+ NELVAKVFDG G + EIR P QGIAGHVATTG++LNI AY HPLFYRGVDD TGF+T+NILCFPI+++ + +GVA+L NKI G +F+K DE++A AFSIYC ISI HSL+YKKV +AQ+RS LANE+MMYHM++ +D+ L I PV+ S+F SF PR++ + DT MA +SM + I+ ++I+ TL +F MVK+ YRDPPYHNWMHAFSV+HF ++ KNL L L ++E+FALF++ +CHD+DHRGTNNSFQV S S+LAALYSSEGSV+ERHHF+Q + ILNT GCN+F+ +K+Y R LDL+RDIILATDLAHHL+IF ++KMA+ GYD + ++H LLLCLLMTS DLSDQTK W+ TR +AELIYKEFF QGDLEKA+GN+P E MDRE+A +P LQI+F++ I P+Y++L L P+ + + RE+W+K+S K + N+ F ++ E
Sbjct: 224 TDRDRKILQLCGELYDLDASSLQLKVLQYLQQETRASRCCLLLVSEDNLQLSCKVIGDKVLGEEVSFPL--TGCLGQVVEDKKSIQLKDLTSEDVQQLQSMLGC-----ELQAMLCVPVISRATDQVVALACAFNKLEGDLFTDEDEHVIQHCFHYTSTVLTSTLAFQKEQKLKCECQALLQVAKNLFTHLDDVSVLLQEIITEARNLSNAEICSVFLLDQ--NELVAKVFDG---------------GVVDDESYEIRIPADQGIAGHVATTGQILNIPDAYAHPLFYRGVDDSTGFRTRNILCFPIKNENQEVIGVAELVNKINGPWFSKFDEDLATAFSIYCGISIAHSLLYKKVNEAQYRSHLANEMMMYHMKVSDDEYTKLLHDGIQPVAAIDSNFASFTYTPRSLPEDDTSMAILSMLQDMNFINNYKIDCPTLARFCLMVKKGYRDPPYHNWMHAFSVSHFCYLLYKNLELTNYLEDIEIFALFISCMCHDLDHRGTNNSFQVASKSVLAALYSSEGSVMERHHFAQAIAILNTHGCNIFDHFSRKDYQRMLDLMRDIILATDLAHHLRIFKDLQKMAEVGYDRNNKQHHRLLLCLLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEKAMGNRPMEMMDREKAYIPELQISFMEHIAMPIYKLLQDLFPKAAELYERVASNREHWTKVSHKFTIRGLPSNNSLDFLDEEYE 921
BLAST of Phosphodiesterase vs. Ensembl Human
Match: PDE2A (phosphodiesterase 2A [Source:HGNC Symbol;Acc:HGNC:8777]) HSP 1 Score: 719.153 bits (1855), Expect = 0.000e+0 Identity = 369/722 (51.11%), Postives = 502/722 (69.53%), Query Frame = 1
Query: 595 SNQINQILELCGSLFDQDAGKLQKKVLSYLIQNTSAETGFLLLVCMDTVELLCQVIGQVIQEDPINFDAEENGIFDKVLKSKTGINLGCLTEAQLREISEIMNASKQETKIQNALCVPVRHQGTNDVIAIVCLINKSGPAQFTNYDEQVINECFKYTTSVLFTTIAYQNERRLKLQTEKMLVVAKNIFSRMDNLNELLLMIMQEARNLTQAERCSVFLVDEDSNELVAKVFDGLPTSSDKNERLRLQDGTEIQQPVEIRFPKAQGIAGHVATTGEMLNIKKAYDHPLFYRGVDDETGFKTKNILCFPIQDDCGKTVGVAQLCNKIKGHFFTKMDEEIAKAFSIYCCISITHSLMYKKVEDAQHRSRLANELMMYHMQIPEDDIAWLSTFSIPPVSIFLSDFESFNSIPRNVKDRDTLMACISMFDGIGLISRWRINRRTLTKFIFMVKRNYRDPPYHNWMHAFSVAHFIFICIKNLPLDKQLTELELFALFVASLCHDIDHRGTNNSFQVQSNSILAALYSSEGSVLERHHFSQTVCILNTEGCNVFESLPQKEYXXXXXXXXXXXXXXXXXHHLQIFSKIEKMAQQGYDNLDSENHNLLLCLLMTSADLSDQTKNWRNTRSVAELIYKEFFRQGDLEKAIGNQPAEQMDRERAVVPNLQIAFLDGIVSPLYRVLSLLHPQTDCINHTIERTRENWSKISQKVASHEIKGNSEEIFRNKLVE 2760
+++ +IL+LCG L+D DA LQ KVL YL Q T A LLLV D ++L C+VIG + + ++F G +V++ K I L LT ++++ ++ ++Q LCVPV + T+ V+A+ C NK FT+ DE VI CF YT++VL +T+A+Q E++LK + + +L VAKN+F+ +D+++ LL I+ EARNL+ AE CSVFL+D+ NELVAKVFDG G + EIR P QGIAGHVATTG++LNI AY HPLFYRGVDD TGF+T+NILCFPI+++ + +GVA+L NKI G +F+K DE++A AFSIYC ISI HSL+YKKV +AQ+RS LANE+MMYHM++ +D+ L I PV+ S+F SF PR++ + DT MA +SM + I+ ++I+ TL +F MVK+ YRDPPYHNWMHAFSV+HF ++ KNL L L ++E+FALF++ +CHD+DHRGTNNSFQV S S+LAALYSSEGSV+ERHHF+Q + ILNT GCN+F+ +K+Y R LDL+RDIILATDLAHHL+IF ++KMA+ GYD + ++H LLLCLLMTS DLSDQTK W+ TR +AELIYKEFF QGDLEKA+GN+P E MDRE+A +P LQI+F++ I P+Y++L L P+ + + RE+W+K+S K + N+ F ++ E
Sbjct: 109 TDRDRKILQLCGELYDLDASSLQLKVLQYLQQETRASRCCLLLVSEDNLQLSCKVIGDKVLGEEVSFPL--TGCLGQVVEDKKSIQLKDLTSEDVQQLQSMLGC-----ELQAMLCVPVISRATDQVVALACAFNKLEGDLFTDEDEHVIQHCFHYTSTVLTSTLAFQKEQKLKCECQALLQVAKNLFTHLDDVSVLLQEIITEARNLSNAEICSVFLLDQ--NELVAKVFDG---------------GVVDDESYEIRIPADQGIAGHVATTGQILNIPDAYAHPLFYRGVDDSTGFRTRNILCFPIKNENQEVIGVAELVNKINGPWFSKFDEDLATAFSIYCGISIAHSLLYKKVNEAQYRSHLANEMMMYHMKVSDDEYTKLLHDGIQPVAAIDSNFASFTYTPRSLPEDDTSMAILSMLQDMNFINNYKIDCPTLARFCLMVKKGYRDPPYHNWMHAFSVSHFCYLLYKNLELTNYLEDIEIFALFISCMCHDLDHRGTNNSFQVASKSVLAALYSSEGSVMERHHFAQAIAILNTHGCNIFDHFSRKDYQRMLDLMRDIILATDLAHHLRIFKDLQKMAEVGYDRNNKQHHRLLLCLLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEKAMGNRPMEMMDREKAYIPELQISFMEHIAMPIYKLLQDLFPKAAELYERVASNREHWTKVSHKFTIRGLPSNNSLDFLDEEYE 806
BLAST of Phosphodiesterase vs. Ensembl Celegans
Match: pde-2 (Probable 3',5'-cyclic phosphodiesterase pde-2 [Source:UniProtKB/Swiss-Prot;Acc:P30645]) HSP 1 Score: 325.479 bits (833), Expect = 8.954e-97 Identity = 193/535 (36.07%), Postives = 311/535 (58.13%), Query Frame = 1
Query: 1168 DNLNELLLMIMQEARNLTQAERCSVFLVDEDSNELVAKVFDGLPTSSDKNERLRLQDGTEIQQPVEIRFPKAQGIAGHVATTGEMLNIKKAYDHPLFYRGVDDETGFKTKNILCFPIQDDCGKTVGVAQLCNKIKGHFFTKMDEEIAKAFSIYCCISITHSLMYKKVEDAQHRSRLANELMMYHMQ--IPEDDIAWLSTFSIPPVSIFLSDFESFNSIPRNVKDRDTLMACISMFDGIGLISRWRINRRTLTKFIFMVKRNYRDPPYHNWMHAFSVAHFIFICIKNLPLDKQLTELELFALFVASLCHDIDHRGTNNSFQVQS--NSILAALYSSEGSVLERHHFSQTVCILNTEGCNVFESLPQKEYXXXXXXXXXXXXXXXXXHHLQIFSKIEKMAQQGYDNLDSENHNLLLCLLMTSADLSDQTKNWRNTRSVAELIYKEFFRQGDLEKAIGNQPAEQMDRERAVVPNLQIAFLDGIVSPLYRVLSLLHPQTDCINHTIERTRENWSKISQKVASHEIKGNSEEIFRNKLVE 2760
+NL+ L+ I+ EA+ T+AE +VFL DED+ ++V +F+ NE + L G +F GI G VA+T +NI+ P F +D++ K +N++ FP+ D +GV L NK G F++ DE+ K FS + SI H+++ K++E+ + R + E + I E DI L + F +F F+ PR+V + A + F+ +G +++N+R L+ + V YR PYHNW HAF+V HF ++ ++ + + L+++E +L +A LCHDIDHRGT NSFQ+QS + L+ LYS+EGSVLERHHF+QT+ +L E C++ E+LP ++ ++ IR++ILATD++ HL+ +I+ M +GY+ + ++ LL+CL+MT++DLSDQ KN+ N + +AE IY EFF QGDLE +G +P E MDR A VP +QI FL I P++++L+ + P+ + I+ W + ++V ++ N+ E R++ +E
Sbjct: 173 NNLSALISCIIAEAKKNTEAEDYAVFLHDEDNKQMV--LFN--------NETM-LMTGK--------KFDMGYGIVGKVASTMRTMNIRDVSRCPFFNEEIDEQFSIKARNLIAFPLIDSSCSLIGVIVLYNKENG--FSRHDEKYIKRFSYFVANSIAHAILAKQIEEVRTRIHMVEEFKIQGEDAVIEEVDIMRLVNDPLRDWRYFSQNFADFSFPPRSVGENHFHRASMMFFEDLGFSMLYKLNKRKLSYLVLRVSAGYRPVPYHNWSHAFAVTHFCWLTLRTDAIRRALSDMERLSLLIACLCHDIDHRGTTNSFQMQSLQKTPLSVLYSTEGSVLERHHFAQTIKLLQQEECSILENLPAADFRTIVNTIREVILATDISAHLRKQERIKTMISEGYNPMSFDHRYLLMCLVMTASDLSDQAKNFHNAKRIAENIYLEFFAQGDLELQLGVKPLEMMDRTNAYVPTVQIDFLFKIGVPVFQLLASVVPEGRTTSEAIDANHLCWVALDEEVRNNPSATNTLEYLRDENLE 686
BLAST of Phosphodiesterase vs. Ensembl Celegans
Match: pde-2 (Probable 3',5'-cyclic phosphodiesterase pde-2 [Source:UniProtKB/Swiss-Prot;Acc:P30645]) HSP 1 Score: 325.479 bits (833), Expect = 9.160e-97 Identity = 193/535 (36.07%), Postives = 311/535 (58.13%), Query Frame = 1
Query: 1168 DNLNELLLMIMQEARNLTQAERCSVFLVDEDSNELVAKVFDGLPTSSDKNERLRLQDGTEIQQPVEIRFPKAQGIAGHVATTGEMLNIKKAYDHPLFYRGVDDETGFKTKNILCFPIQDDCGKTVGVAQLCNKIKGHFFTKMDEEIAKAFSIYCCISITHSLMYKKVEDAQHRSRLANELMMYHMQ--IPEDDIAWLSTFSIPPVSIFLSDFESFNSIPRNVKDRDTLMACISMFDGIGLISRWRINRRTLTKFIFMVKRNYRDPPYHNWMHAFSVAHFIFICIKNLPLDKQLTELELFALFVASLCHDIDHRGTNNSFQVQS--NSILAALYSSEGSVLERHHFSQTVCILNTEGCNVFESLPQKEYXXXXXXXXXXXXXXXXXHHLQIFSKIEKMAQQGYDNLDSENHNLLLCLLMTSADLSDQTKNWRNTRSVAELIYKEFFRQGDLEKAIGNQPAEQMDRERAVVPNLQIAFLDGIVSPLYRVLSLLHPQTDCINHTIERTRENWSKISQKVASHEIKGNSEEIFRNKLVE 2760
+NL+ L+ I+ EA+ T+AE +VFL DED+ ++V +F+ NE + L G +F GI G VA+T +NI+ P F +D++ K +N++ FP+ D +GV L NK G F++ DE+ K FS + SI H+++ K++E+ + R + E + I E DI L + F +F F+ PR+V + A + F+ +G +++N+R L+ + V YR PYHNW HAF+V HF ++ ++ + + L+++E +L +A LCHDIDHRGT NSFQ+QS + L+ LYS+EGSVLERHHF+QT+ +L E C++ E+LP ++ ++ IR++ILATD++ HL+ +I+ M +GY+ + ++ LL+CL+MT++DLSDQ KN+ N + +AE IY EFF QGDLE +G +P E MDR A VP +QI FL I P++++L+ + P+ + I+ W + ++V ++ N+ E R++ +E
Sbjct: 176 NNLSALISCIIAEAKKNTEAEDYAVFLHDEDNKQMV--LFN--------NETM-LMTGK--------KFDMGYGIVGKVASTMRTMNIRDVSRCPFFNEEIDEQFSIKARNLIAFPLIDSSCSLIGVIVLYNKENG--FSRHDEKYIKRFSYFVANSIAHAILAKQIEEVRTRIHMVEEFKIQGEDAVIEEVDIMRLVNDPLRDWRYFSQNFADFSFPPRSVGENHFHRASMMFFEDLGFSMLYKLNKRKLSYLVLRVSAGYRPVPYHNWSHAFAVTHFCWLTLRTDAIRRALSDMERLSLLIACLCHDIDHRGTTNSFQMQSLQKTPLSVLYSTEGSVLERHHFAQTIKLLQQEECSILENLPAADFRTIVNTIREVILATDISAHLRKQERIKTMISEGYNPMSFDHRYLLMCLVMTASDLSDQAKNFHNAKRIAENIYLEFFAQGDLELQLGVKPLEMMDRTNAYVPTVQIDFLFKIGVPVFQLLASVVPEGRTTSEAIDANHLCWVALDEEVRNNPSATNTLEYLRDENLE 689
BLAST of Phosphodiesterase vs. Ensembl Celegans
Match: pde-5 (Probable 3',5'-cyclic phosphodiesterase pde-5 [Source:UniProtKB/Swiss-Prot;Acc:P91119]) HSP 1 Score: 305.449 bits (781), Expect = 2.305e-90 Identity = 182/525 (34.67%), Postives = 307/525 (58.48%), Query Frame = 1
Query: 1132 MLVVAKNIFSRMDNLNELLLMIMQEARNLTQAERCSVFLVDEDSNELVAKVFDGLPTSSDKNERLRLQDGTEIQQPVEIRFPKAQGIAGHVATTGEMLNIKKAYDHPLFYRGVDDETGFKTKNILCFPIQDDCGKTVGVAQLCNKIKGHFFTKMDEEIAKAFSIYCCISITHSLMYKKVEDAQHRSRLANELMMYHMQIPEDDIAWLSTFSIPPVSIFLSDFESFNSIPRNVKDRDTLMACISMFDGIGLISRWRINRRTLTKFIFMVKRNYRDPPYHNWMHAFSVAHFIFICIKNLPLDKQLTELELFALFVASLCHDIDHRGTNNSFQVQSNSILAALYSSEGSVLERHHFSQTVCILNTEGCNVFESLPQKEYXXXXXXXXXXXXXXXXXHHLQIFSKIEKMAQQGYDNLDSENHNLLL-CLLMTSADLSDQTKNWRNTRSVAELIYKEFFRQGDLEKAIGNQPAEQMDRERA-VVPNLQIAFLDGIVSPLYRVLSLLHPQTDCINHTIERTRENWSKISQK 2700
+L VA++IF + +++ +++ +M A+ L A+R S+FLVD + ++ A++FD + E +R+ +E Q+ EIRF ++GIAG+VA+TGE LNI+ AY+ F VD +TG+ TK ILC PI G +GV Q+ NK G FT+ DE+ + F++YC +++ H+ +Y K+ ++ + R+A E++ YH D++ L I + L + FN + + + + + + MF + R + L +F+ V++NYR YHNW H +SVAH +F + N P T+LE AL+V+ LCHD+DHRG NN++ ++ LA++YS+ SV+ERHHF+QTV IL +G N+ +SL ++Y + L LI+ ILATDLA +K+ + +++ + H LL ++MT DL K W ++I++EF+ QGD E+ G +P MDR++A ++P +Q+ F+ GI P Y +++ + P+ D + E + W +++++
Sbjct: 201 LLDVARSIFHDIVSMDAVIIKVMNFAQKLVDADRASLFLVDSKNAQIYARIFD---VGTGDEEHVRV--NSEGQK--EIRFDMSKGIAGYVASTGEGLNIENAYEDERFNADVDSKTGYTTKTILCMPILIR-GIVIGVVQMVNKHDG-VFTRQDEDAFEIFAVYCGLALHHAKLYDKIRRSEQKYRVALEVLAYHSVCNADEVNKLKKIEINNRIVELETID-FNGM--RLSELEKPLYAVYMFKTL-FADTLRFDTEDLIRFVLTVRKNYRRVAYHNWAHGWSVAHAMFATLMNSP--DAFTKLEALALYVSCLCHDLDHRGKNNAYMKTMSTPLASIYST--SVMERHHFNQTVTILQQDGHNILKSLSSEDYKKTLSLIKHCILATDLALFFSNKAKLNVILDNNTFDINRQEHRLLTQAVMMTGCDLVASAKPWNIQTETVKVIFEEFYDQGDAERLSGKEPIPMMDRQQAHMLPQMQVGFMRGICMPCYDLIARIFPKNDKMRERCEYNAKKWEELAEE 708
BLAST of Phosphodiesterase vs. Ensembl Celegans
Match: pde-4 (Probable 3',5'-cyclic phosphodiesterase pde-4 [Source:UniProtKB/Swiss-Prot;Acc:Q22000]) HSP 1 Score: 121.709 bits (304), Expect = 1.838e-28 Identity = 87/291 (29.90%), Postives = 156/291 (53.61%), Query Frame = 1
Query: 1828 KDRDTLMACISMFDGIGLISRWRINRRTLTKFIFMVKRNYRDPPYHNWMHAFSVAHFIFICIKNLPLDKQLTELELFALFVASLCHDIDHRGTNNSFQVQSNSILAALYSSEGSVLERHHFSQTVCILNTEGCNVFESLPQKEYXXXXXXXXXXXXXXXXXHHLQIFSKIEKM--AQQGYDN----LDSENHNL-LLCLLMTSADLSDQTKNWRNTRSVAELIYKEFFRQGDLEKAIGNQPAEQMDRERAVVPNLQIAFLDGIVSPLYRVLS-LLHPQTDCINHTIERTRE 2676
K+ + S+ L + I++ TL ++ ++ +YR+ YHN++HA VA + + + + L + T+LE+ A A HD+DH G N + + SN+ LA +Y+ E SVLE+HH + +L C+ +L +K+ ++ ++ D++LATD++ H+ + + ++ M A++ N LD N + +L ++ ADLS+ TK + + I +E++RQGD EK +G + + DR + Q+ F+D IV PLY + L++P I +E RE
Sbjct: 237 KNHSLTVVTFSLLRQRNLFKTFEIHQSTLVTYLLNLEHHYRNNHYHNFIHAADVAQSMHVLLMSPVLTEVFTDLEVLAAIFAGAVHDVDHPGFTNQYLINSNNELAIMYNDE-SVLEQHHLAVAFKLLQDSNCDFLANLSRKQRLQFRKIVIDMVLATDMSKHMSLLADLKTMVEAKKVAGNNVIVLDKYNDKIQVLQSMIHLADLSNPTKPIELYQQWNQRIMEEYWRQGDKEKELGLEISPMCDRGNVTIEKSQVGFIDYIVHPLYETWADLVYPDAQNILDQLEENRE 526
BLAST of Phosphodiesterase vs. Ensembl Celegans
Match: pde-4 (Probable 3',5'-cyclic phosphodiesterase pde-4 [Source:UniProtKB/Swiss-Prot;Acc:Q22000]) HSP 1 Score: 121.709 bits (304), Expect = 3.096e-28 Identity = 87/291 (29.90%), Postives = 156/291 (53.61%), Query Frame = 1
Query: 1828 KDRDTLMACISMFDGIGLISRWRINRRTLTKFIFMVKRNYRDPPYHNWMHAFSVAHFIFICIKNLPLDKQLTELELFALFVASLCHDIDHRGTNNSFQVQSNSILAALYSSEGSVLERHHFSQTVCILNTEGCNVFESLPQKEYXXXXXXXXXXXXXXXXXHHLQIFSKIEKM--AQQGYDN----LDSENHNL-LLCLLMTSADLSDQTKNWRNTRSVAELIYKEFFRQGDLEKAIGNQPAEQMDRERAVVPNLQIAFLDGIVSPLYRVLS-LLHPQTDCINHTIERTRE 2676
K+ + S+ L + I++ TL ++ ++ +YR+ YHN++HA VA + + + + L + T+LE+ A A HD+DH G N + + SN+ LA +Y+ E SVLE+HH + +L C+ +L +K+ ++ ++ D++LATD++ H+ + + ++ M A++ N LD N + +L ++ ADLS+ TK + + I +E++RQGD EK +G + + DR + Q+ F+D IV PLY + L++P I +E RE
Sbjct: 287 KNHSLTVVTFSLLRQRNLFKTFEIHQSTLVTYLLNLEHHYRNNHYHNFIHAADVAQSMHVLLMSPVLTEVFTDLEVLAAIFAGAVHDVDHPGFTNQYLINSNNELAIMYNDE-SVLEQHHLAVAFKLLQDSNCDFLANLSRKQRLQFRKIVIDMVLATDMSKHMSLLADLKTMVEAKKVAGNNVIVLDKYNDKIQVLQSMIHLADLSNPTKPIELYQQWNQRIMEEYWRQGDKEKELGLEISPMCDRGNVTIEKSQVGFIDYIVHPLYETWADLVYPDAQNILDQLEENRE 576
BLAST of Phosphodiesterase vs. Ensembl Fly
Match: Pde11 (gene:FBgn0085370 transcript:FBtr0303163) HSP 1 Score: 316.62 bits (810), Expect = 2.259e-91 Identity = 203/599 (33.89%), Postives = 323/599 (53.92%), Query Frame = 1
Query: 937 LCVPVRHQGTNDVIAIVCLINKSGPAQFTNYDEQVINECFKYTTSVLFTTIAYQNERRLKLQTEKMLVVAKNIFSRMDNLNELLLMIMQEARNLTQAERCSVFLVDEDSNELVAKVFDGLPTSSDKNERLRLQDGTEIQQPVEIRFPKAQGIAGHVATTGEMLNIKKAYDHPLFYRGVDDETGFKTKNILCFPIQDDCGKTVGVAQLCNKIKGHFFTKMDEEIAKAFSIYCCISITHSLMYKKVEDAQHRSRLANELMMYHMQIPEDDIAWLSTFSIPPVSIF-LSDFESFNSIPRNVKDRDTLMACISMFDGIGLISRWRINRRTLTKFIFMVKRNYRDPPYHNWMHAFSVAHFIFICIKNLPLDKQLTELELFALFVASLCHDIDHRGTNNSFQVQSNSILAALYSSEGSVLERHHFSQTVCILNTEGCNVFESLPQKEYXXXXXXXXXXXXXXXXXHHLQIFSK-----IEKMAQQGYDNLDSENHNLLLCLLMTSADLSDQTKNWRNTRSVAELIYKEFFRQGDLEKAIGN-QPAEQMDRERA-VVPNLQIAFLDGIVSPLYRVLSLLHPQTDCINHTIERTRENWSKISQKVAS 2709
LC+P++ + DVI + +INK F+ DE+V + ++ L Y+ + + + +L +A+ IF + ++ I+ ++L Q +R + LV E ++VFD ++D +E ++ T P E RFP GI GHVATTGE +N+ AY+ F VD+ + FK ++ILC I++ G+ +GV QL NK FTK DE +AF+I+C + I ++ MY+K A + + E++ YH D+ L +P F L DF+ F+ I + +D DTL AC+ MF + + R+ I+ L +++ VK+NYR+ YHNW HAF+VA +F + K E+E AL + LCHD+DHRGTNNSFQ++++S LA LYS+ S +E HHF Q + ILN+ G + +L +Y R + ++ D IL+TD L ++ K +E ++Q + E LL + MT DLS TK W + VA+L+ EFF QGD+EK N P + M+RE+ +P +Q+ F+D I P+Y + L + + + + R +W ++ V +
Sbjct: 483 LCMPIK-DSSGDVIGVAQVINKMNGECFSEIDEKVFSSYLQFCGIGLRNAQLYEKSQLEIKRNQVLLDLARMIFEEQSTIEHMVFRILTHMQSLIQCQRVQILLVHEADKGSFSRVFDF--EANDLSE----EEATSRTSPYESRFPINIGITGHVATTGETVNVPNAYEDDRFDASVDENSCFKHRSILCMAIKNSLGQIIGVIQLINKFNELDFTKNDENFVEAFAIFCGMGIHNTHMYEKAIVAMAKQSVTLEVLSYHASATMDEAHRLRRLRVPSAVHFRLHDFK-FDDI--HFEDDDTLKACLRMFLDLDFVERFHIDYEVLCRWLLSVKKNYRNVTYHNWRHAFNVAQMMFAILTTTQWWKIFGEIECLALIIGCLCHDLDHRGTNNSFQIKASSPLAQLYST--STMEHHHFDQCLMILNSPGNQILANLSSDDYCRVIRVLEDAILSTD----LAVYFKKRGPFLESVSQPTSYWVAEEPRALLRAMSMTVCDLSAITKPWEIEKRVADLVSSEFFEQGDMEKQELNITPIDIMNREKEDELPMMQVNFIDSICLPIYEAFATLSDKLEPLVEGVRDNRGHWIDLADVVKT 1065
BLAST of Phosphodiesterase vs. Ensembl Fly
Match: Pde11 (gene:FBgn0085370 transcript:FBtr0303162) HSP 1 Score: 317.005 bits (811), Expect = 2.910e-91 Identity = 203/599 (33.89%), Postives = 322/599 (53.76%), Query Frame = 1
Query: 937 LCVPVRHQGTNDVIAIVCLINKSGPAQFTNYDEQVINECFKYTTSVLFTTIAYQNERRLKLQTEKMLVVAKNIFSRMDNLNELLLMIMQEARNLTQAERCSVFLVDEDSNELVAKVFDGLPTSSDKNERLRLQDGTEIQQPVEIRFPKAQGIAGHVATTGEMLNIKKAYDHPLFYRGVDDETGFKTKNILCFPIQDDCGKTVGVAQLCNKIKGHFFTKMDEEIAKAFSIYCCISITHSLMYKKVEDAQHRSRLANELMMYHMQIPEDDIAWLSTFSIPPVSIF-LSDFESFNSIPRNVKDRDTLMACISMFDGIGLISRWRINRRTLTKFIFMVKRNYRDPPYHNWMHAFSVAHFIFICIKNLPLDKQLTELELFALFVASLCHDIDHRGTNNSFQVQSNSILAALYSSEGSVLERHHFSQTVCILNTEGCNVFESLPQKEYXXXXXXXXXXXXXXXXXHHLQIFSK-----IEKMAQQGYDNLDSENHNLLLCLLMTSADLSDQTKNWRNTRSVAELIYKEFFRQGDLEKAIGN-QPAEQMDRERA-VVPNLQIAFLDGIVSPLYRVLSLLHPQTDCINHTIERTRENWSKISQKVAS 2709
LC+P++ + DVI + +INK F+ DE+V + ++ L Y+ + + + +L +A+ IF + ++ I+ ++L Q +R + LV E ++VFD + N+ L ++ T P E RFP GI GHVATTGE +N+ AY+ F VD+ + FK ++ILC I++ G+ +GV QL NK FTK DE +AF+I+C + I ++ MY+K A + + E++ YH D+ L +P F L DF+ F+ I + +D DTL AC+ MF + + R+ I+ L +++ VK+NYR+ YHNW HAF+VA +F + K E+E AL + LCHD+DHRGTNNSFQ++++S LA LYS+ S +E HHF Q + ILN+ G + +L +Y R + ++ D IL+TD L ++ K +E ++Q + E LL + MT DLS TK W + VA+L+ EFF QGD+EK N P + M+RE+ +P +Q+ F+D I P+Y + L + + + + R +W ++ V +
Sbjct: 527 LCMPIK-DSSGDVIGVAQVINKMNGECFSEIDEKVFSSYLQFCGIGLRNAQLYEKSQLEIKRNQVLLDLARMIFEEQSTIEHMVFRILTHMQSLIQCQRVQILLVHEADKGSFSRVFD-----FEAND-LSEEEATSRTSPYESRFPINIGITGHVATTGETVNVPNAYEDDRFDASVDENSCFKHRSILCMAIKNSLGQIIGVIQLINKFNELDFTKNDENFVEAFAIFCGMGIHNTHMYEKAIVAMAKQSVTLEVLSYHASATMDEAHRLRRLRVPSAVHFRLHDFK-FDDI--HFEDDDTLKACLRMFLDLDFVERFHIDYEVLCRWLLSVKKNYRNVTYHNWRHAFNVAQMMFAILTTTQWWKIFGEIECLALIIGCLCHDLDHRGTNNSFQIKASSPLAQLYST--STMEHHHFDQCLMILNSPGNQILANLSSDDYCRVIRVLEDAILSTD----LAVYFKKRGPFLESVSQPTSYWVAEEPRALLRAMSMTVCDLSAITKPWEIEKRVADLVSSEFFEQGDMEKQELNITPIDIMNREKEDELPMMQVNFIDSICLPIYEAFATLSDKLEPLVEGVRDNRGHWIDLADVVKT 1109
BLAST of Phosphodiesterase vs. Ensembl Fly
Match: Pde11 (gene:FBgn0085370 transcript:FBtr0343831) HSP 1 Score: 315.464 bits (807), Expect = 8.685e-90 Identity = 203/599 (33.89%), Postives = 322/599 (53.76%), Query Frame = 1
Query: 937 LCVPVRHQGTNDVIAIVCLINKSGPAQFTNYDEQVINECFKYTTSVLFTTIAYQNERRLKLQTEKMLVVAKNIFSRMDNLNELLLMIMQEARNLTQAERCSVFLVDEDSNELVAKVFDGLPTSSDKNERLRLQDGTEIQQPVEIRFPKAQGIAGHVATTGEMLNIKKAYDHPLFYRGVDDETGFKTKNILCFPIQDDCGKTVGVAQLCNKIKGHFFTKMDEEIAKAFSIYCCISITHSLMYKKVEDAQHRSRLANELMMYHMQIPEDDIAWLSTFSIPPVSIF-LSDFESFNSIPRNVKDRDTLMACISMFDGIGLISRWRINRRTLTKFIFMVKRNYRDPPYHNWMHAFSVAHFIFICIKNLPLDKQLTELELFALFVASLCHDIDHRGTNNSFQVQSNSILAALYSSEGSVLERHHFSQTVCILNTEGCNVFESLPQKEYXXXXXXXXXXXXXXXXXHHLQIFSK-----IEKMAQQGYDNLDSENHNLLLCLLMTSADLSDQTKNWRNTRSVAELIYKEFFRQGDLEKAIGN-QPAEQMDRERA-VVPNLQIAFLDGIVSPLYRVLSLLHPQTDCINHTIERTRENWSKISQKVAS 2709
LC+P++ + DVI + +INK F+ DE+V + ++ L Y+ + + + +L +A+ IF + ++ I+ ++L Q +R + LV E ++VFD + N+ L ++ T P E RFP GI GHVATTGE +N+ AY+ F VD+ + FK ++ILC I++ G+ +GV QL NK FTK DE +AF+I+C + I ++ MY+K A + + E++ YH D+ L +P F L DF+ F+ I + +D DTL AC+ MF + + R+ I+ L +++ VK+NYR+ YHNW HAF+VA +F + K E+E AL + LCHD+DHRGTNNSFQ++++S LA LYS+ S +E HHF Q + ILN+ G + +L +Y R + ++ D IL+TD L ++ K +E ++Q + E LL + MT DLS TK W + VA+L+ EFF QGD+EK N P + M+RE+ +P +Q+ F+D I P+Y + L + + + + R +W ++ V +
Sbjct: 483 LCMPIK-DSSGDVIGVAQVINKMNGECFSEIDEKVFSSYLQFCGIGLRNAQLYEKSQLEIKRNQVLLDLARMIFEEQSTIEHMVFRILTHMQSLIQCQRVQILLVHEADKGSFSRVFD-----FEAND-LSEEEATSRTSPYESRFPINIGITGHVATTGETVNVPNAYEDDRFDASVDENSCFKHRSILCMAIKNSLGQIIGVIQLINKFNELDFTKNDENFVEAFAIFCGMGIHNTHMYEKAIVAMAKQSVTLEVLSYHASATMDEAHRLRRLRVPSAVHFRLHDFK-FDDI--HFEDDDTLKACLRMFLDLDFVERFHIDYEVLCRWLLSVKKNYRNVTYHNWRHAFNVAQMMFAILTTTQWWKIFGEIECLALIIGCLCHDLDHRGTNNSFQIKASSPLAQLYST--STMEHHHFDQCLMILNSPGNQILANLSSDDYCRVIRVLEDAILSTD----LAVYFKKRGPFLESVSQPTSYWVAEEPRALLRAMSMTVCDLSAITKPWEIEKRVADLVSSEFFEQGDMEKQELNITPIDIMNREKEDELPMMQVNFIDSICLPIYEAFATLSDKLEPLVEGVRDNRGHWIDLADVVKT 1065
BLAST of Phosphodiesterase vs. Ensembl Fly
Match: Pde11 (gene:FBgn0085370 transcript:FBtr0112545) HSP 1 Score: 315.464 bits (807), Expect = 8.685e-90 Identity = 203/599 (33.89%), Postives = 322/599 (53.76%), Query Frame = 1
Query: 937 LCVPVRHQGTNDVIAIVCLINKSGPAQFTNYDEQVINECFKYTTSVLFTTIAYQNERRLKLQTEKMLVVAKNIFSRMDNLNELLLMIMQEARNLTQAERCSVFLVDEDSNELVAKVFDGLPTSSDKNERLRLQDGTEIQQPVEIRFPKAQGIAGHVATTGEMLNIKKAYDHPLFYRGVDDETGFKTKNILCFPIQDDCGKTVGVAQLCNKIKGHFFTKMDEEIAKAFSIYCCISITHSLMYKKVEDAQHRSRLANELMMYHMQIPEDDIAWLSTFSIPPVSIF-LSDFESFNSIPRNVKDRDTLMACISMFDGIGLISRWRINRRTLTKFIFMVKRNYRDPPYHNWMHAFSVAHFIFICIKNLPLDKQLTELELFALFVASLCHDIDHRGTNNSFQVQSNSILAALYSSEGSVLERHHFSQTVCILNTEGCNVFESLPQKEYXXXXXXXXXXXXXXXXXHHLQIFSK-----IEKMAQQGYDNLDSENHNLLLCLLMTSADLSDQTKNWRNTRSVAELIYKEFFRQGDLEKAIGN-QPAEQMDRERA-VVPNLQIAFLDGIVSPLYRVLSLLHPQTDCINHTIERTRENWSKISQKVAS 2709
LC+P++ + DVI + +INK F+ DE+V + ++ L Y+ + + + +L +A+ IF + ++ I+ ++L Q +R + LV E ++VFD + N+ L ++ T P E RFP GI GHVATTGE +N+ AY+ F VD+ + FK ++ILC I++ G+ +GV QL NK FTK DE +AF+I+C + I ++ MY+K A + + E++ YH D+ L +P F L DF+ F+ I + +D DTL AC+ MF + + R+ I+ L +++ VK+NYR+ YHNW HAF+VA +F + K E+E AL + LCHD+DHRGTNNSFQ++++S LA LYS+ S +E HHF Q + ILN+ G + +L +Y R + ++ D IL+TD L ++ K +E ++Q + E LL + MT DLS TK W + VA+L+ EFF QGD+EK N P + M+RE+ +P +Q+ F+D I P+Y + L + + + + R +W ++ V +
Sbjct: 483 LCMPIK-DSSGDVIGVAQVINKMNGECFSEIDEKVFSSYLQFCGIGLRNAQLYEKSQLEIKRNQVLLDLARMIFEEQSTIEHMVFRILTHMQSLIQCQRVQILLVHEADKGSFSRVFD-----FEAND-LSEEEATSRTSPYESRFPINIGITGHVATTGETVNVPNAYEDDRFDASVDENSCFKHRSILCMAIKNSLGQIIGVIQLINKFNELDFTKNDENFVEAFAIFCGMGIHNTHMYEKAIVAMAKQSVTLEVLSYHASATMDEAHRLRRLRVPSAVHFRLHDFK-FDDI--HFEDDDTLKACLRMFLDLDFVERFHIDYEVLCRWLLSVKKNYRNVTYHNWRHAFNVAQMMFAILTTTQWWKIFGEIECLALIIGCLCHDLDHRGTNNSFQIKASSPLAQLYST--STMEHHHFDQCLMILNSPGNQILANLSSDDYCRVIRVLEDAILSTD----LAVYFKKRGPFLESVSQPTSYWVAEEPRALLRAMSMTVCDLSAITKPWEIEKRVADLVSSEFFEQGDMEKQELNITPIDIMNREKEDELPMMQVNFIDSICLPIYEAFATLSDKLEPLVEGVRDNRGHWIDLADVVKT 1065
BLAST of Phosphodiesterase vs. Ensembl Fly
Match: Pde11 (gene:FBgn0085370 transcript:FBtr0112544) HSP 1 Score: 315.849 bits (808), Expect = 9.129e-90 Identity = 203/599 (33.89%), Postives = 322/599 (53.76%), Query Frame = 1
Query: 937 LCVPVRHQGTNDVIAIVCLINKSGPAQFTNYDEQVINECFKYTTSVLFTTIAYQNERRLKLQTEKMLVVAKNIFSRMDNLNELLLMIMQEARNLTQAERCSVFLVDEDSNELVAKVFDGLPTSSDKNERLRLQDGTEIQQPVEIRFPKAQGIAGHVATTGEMLNIKKAYDHPLFYRGVDDETGFKTKNILCFPIQDDCGKTVGVAQLCNKIKGHFFTKMDEEIAKAFSIYCCISITHSLMYKKVEDAQHRSRLANELMMYHMQIPEDDIAWLSTFSIPPVSIF-LSDFESFNSIPRNVKDRDTLMACISMFDGIGLISRWRINRRTLTKFIFMVKRNYRDPPYHNWMHAFSVAHFIFICIKNLPLDKQLTELELFALFVASLCHDIDHRGTNNSFQVQSNSILAALYSSEGSVLERHHFSQTVCILNTEGCNVFESLPQKEYXXXXXXXXXXXXXXXXXHHLQIFSK-----IEKMAQQGYDNLDSENHNLLLCLLMTSADLSDQTKNWRNTRSVAELIYKEFFRQGDLEKAIGN-QPAEQMDRERA-VVPNLQIAFLDGIVSPLYRVLSLLHPQTDCINHTIERTRENWSKISQKVAS 2709
LC+P++ + DVI + +INK F+ DE+V + ++ L Y+ + + + +L +A+ IF + ++ I+ ++L Q +R + LV E ++VFD + N+ L ++ T P E RFP GI GHVATTGE +N+ AY+ F VD+ + FK ++ILC I++ G+ +GV QL NK FTK DE +AF+I+C + I ++ MY+K A + + E++ YH D+ L +P F L DF+ F+ I + +D DTL AC+ MF + + R+ I+ L +++ VK+NYR+ YHNW HAF+VA +F + K E+E AL + LCHD+DHRGTNNSFQ++++S LA LYS+ S +E HHF Q + ILN+ G + +L +Y R + ++ D IL+TD L ++ K +E ++Q + E LL + MT DLS TK W + VA+L+ EFF QGD+EK N P + M+RE+ +P +Q+ F+D I P+Y + L + + + + R +W ++ V +
Sbjct: 527 LCMPIK-DSSGDVIGVAQVINKMNGECFSEIDEKVFSSYLQFCGIGLRNAQLYEKSQLEIKRNQVLLDLARMIFEEQSTIEHMVFRILTHMQSLIQCQRVQILLVHEADKGSFSRVFD-----FEAND-LSEEEATSRTSPYESRFPINIGITGHVATTGETVNVPNAYEDDRFDASVDENSCFKHRSILCMAIKNSLGQIIGVIQLINKFNELDFTKNDENFVEAFAIFCGMGIHNTHMYEKAIVAMAKQSVTLEVLSYHASATMDEAHRLRRLRVPSAVHFRLHDFK-FDDI--HFEDDDTLKACLRMFLDLDFVERFHIDYEVLCRWLLSVKKNYRNVTYHNWRHAFNVAQMMFAILTTTQWWKIFGEIECLALIIGCLCHDLDHRGTNNSFQIKASSPLAQLYST--STMEHHHFDQCLMILNSPGNQILANLSSDDYCRVIRVLEDAILSTD----LAVYFKKRGPFLESVSQPTSYWVAEEPRALLRAMSMTVCDLSAITKPWEIEKRVADLVSSEFFEQGDMEKQELNITPIDIMNREKEDELPMMQVNFIDSICLPIYEAFATLSDKLEPLVEGVRDNRGHWIDLADVVKT 1109
BLAST of Phosphodiesterase vs. Ensembl Zebrafish
Match: pde11a (phosphodiesterase 11a [Source:ZFIN;Acc:ZDB-GENE-070912-207]) HSP 1 Score: 299.286 bits (765), Expect = 1.504e-86 Identity = 189/599 (31.55%), Postives = 319/599 (53.26%), Query Frame = 1
Query: 922 KIQNALCVPVRHQGTNDVIAIVCLINKS-GPAQFTNYDEQVINECFKYTTSVLFTTIAYQNERRLKLQTEKMLVVAKNIFSRMDNLNELLLMIMQEARNLTQAERCSVFLVDEDSNELV--AKVFDGLPTSSDKNERLRLQDGTEIQQPVEIRFPKAQGIAGHVATTGEMLNIKKAYDHPLFYRGVDDETGFKTKNILCFPIQDDCGKTVGVAQLCNKIKGHFFTKMDEEIAKAFSIYCCISITHSLMYKKVEDAQHRSRLANELMMYHMQIPEDDIAWLSTFSIPPVSIFLSDFESFNSIPRNVKDRDTLMACISMFDGIGLISRWRINRRTLTKFIFMVKRNYRDPPYHNWMHAFSVAHFIFICIKNLPLDKQLTELELFALFVASLCHDIDHRGTNNSFQVQSNSILAALYSSEGSVLERHHFSQTVCILNTEGCNVFESLPQKEYXXXXXXXXXXXXXXXXXHHLQIFSKIEKMAQQGYDNLDSENHN-LLLCLLMTSADLSDQTKNWRNTRSVAELIYKEFFRQGDLEKA-IGNQPAEQMDRERA-VVPNLQIAFLDGIVSPLYRVLSLLHPQTDCINHTIERTRENWSKISQK 2700
K ++ LC+P+ H +VI + INKS A FT DE+V+ + + + R+ ++ +L V ++F +L +++ IM A+ L + ERCSV L+++ + +V K F+ L + +D + + + IA VA+TG +NI AY P F D +GF +++LC PI + + +GVAQ+ N++ G F D+ + +AF I+C + I +++MY +V+ + + +A +++ YH + ++ +IP V D SF+ +V T A + MF +G++ +++I+ TL +++ V++NYR YHNW HAF+V +F + + LTE+E AL V +CHD+DHRGTNN+FQ ++ S L+ LY + + LE HHF+ V IL +EG N+F +L EY + L++ ILATDL + Q + ++ +G N + + H + +LMT+ DL TK W + VAEL+ EFF QGD E++ + P+ DR R +P LQ+ ++DGI +PLY + L+P+ + I+ R W ++ +
Sbjct: 269 KTKSLLCMPI-HNSDGEVIGVAQAINKSPNGALFTQDDEKVLQMYLPFCGIAISNAQLFAASRKEYDRSRALLEVVNDLFEEQTDLEKIVRKIMHRAQTLLKCERCSVQLLEDIESPVVKFTKSFELLSPKCSADMENSFKDSMDKSSYSDWLINNS--IAELVASTGLPVNISDAYQDPRFDAEADQFSGFHIRSVLCVPIWNSNHQIIGVAQVLNRLDGKPFDDADQRLFEAFVIFCGLGINNTIMYDQVKKSWAKQSVALDVLSYHATCSKTEVDKFKAANIPLVCELGIDKLSFDDFSLDVDAMVT--AALRMFMELGMVQKFKIDYETLCRWLLTVRKNYRMVLYHNWRHAFNVCQCMFSMLTTAGFQETLTEMETLALIVGCICHDLDHRGTNNAFQAKTGSALSLLYGTSAT-LEHHHFNHAVMILQSEGHNIFSNLSSHEYGELMQLLKQSILATDLTLYFQNRNSFFELVNKGEYNWNVKEHREMCRSMLMTACDLGAVTKPWEISHKVAELVTSEFFEQGDRERSELKLTPSAIFDRNRKDELPGLQLEWIDGICAPLYETFAKLNPKLQPMMDLIKANRAKWEELHHR 861 HSP 2 Score: 98.9821 bits (245), Expect = 1.692e-20 Identity = 67/211 (31.75%), Postives = 110/211 (52.13%), Query Frame = 1
Query: 1081 TTIAYQNERRLKLQTEKMLVVAKNIFSRMDNLNELLLMIMQEARNLTQAERCSVFLVDEDSNE--LVAKVFDGLPTSSDKNERLRLQDGTEIQQPV----EIRFPKAQGIAGHVATTGEMLNIKKAYDHPLFYRGVDDETGFKTKNILCFPIQDDCGKTVGVAQLCNK-IKGHFFTKMDEEIAKAFSIYCCISITHSLMYKKVEDAQHRSR 1692
T + Y+ + + E L + K+I + +D L L I+ + A+RCS+FLV+ +N+ LV+K FD + GT + + E++ P +GI G+VA GE +NI AY F +D TG+KTK++LC PI + G+ +GVAQ NK G FT+ DE++ + + +C I+I+++ ++ RSR
Sbjct: 141 TAVDYKYYLKEHNEREFFLELVKDISNDLD-LTSLSYKILVFVCIMVDADRCSLFLVEGPTNKKTLVSKFFD-------------VHAGTTVLPSLSNSDEVQVPWGKGIIGYVAEHGETVNIPDAYQDHRFSDEIDKLTGYKTKSLLCMPIHNSDGEVIGVAQAINKSPNGALFTQDDEKVLQMYLPFCGIAISNAQLFAASRKEYDRSR 337
BLAST of Phosphodiesterase vs. Ensembl Zebrafish
Match: pde10a (phosphodiesterase 10A [Source:ZFIN;Acc:ZDB-GENE-040426-1115]) HSP 1 Score: 294.664 bits (753), Expect = 6.163e-86 Identity = 204/579 (35.23%), Postives = 311/579 (53.71%), Query Frame = 1
Query: 922 KIQNALCVPVRHQGTNDVIAIVCLINKSGPAQFTNYDEQVINECFKYTTSVLFTTIAYQNERRLKLQTEK---MLVVAKNIFSRMDNLNELLLMIMQEARNLTQAERCSVFLVDEDSNELVAKVFDGLPTSSDKNERLRLQDGTEI-QQPVEIRFPKAQGIAGHVATTGEMLNIKKAYDHPLFYRGVDDETGFKTKNILCFPIQDDCGKTVGVAQLCNKIKGHFFTKMDEEIAKAFSIYCCISITHSLMYKKVEDAQHRSRLANELMMYHMQIPEDDIAWLSTFSIPPVSIFLSDFESFNSIPRNVKDRDTLMACISMFDGIGLISRWRINRRTLTKFIFMVKRNYRDPPYHNWMHAFSVAHFIFICIKNLPLDKQLTELELFALFVASLCHDIDHRGTNNSFQVQSNSILAALYSSEGSVLERHHFSQTVCILNTEGCNVFESLPQKEYXXXXXXXXXXXXXXXXXHHLQIFSKIEKMAQQGYDNLDSENH-NLLLCLLMTSADLSDQTKNWRNTRSVAELIYKEFFRQGDLEKAIGNQPAEQMDRERA-VVPNLQIAFLDGIVSPLYRVLSLLHPQT 2640
++ + LC+P+ D+IAI+ L G F ++V + + + Q R L QTE +L V+K F + ++ LL IM A+NL A+RC++F VD ++ EL + +FD ++NE G + ++ EIRF +GIAG VA TGE+LNI AY P F R VD TG+ T+NILC PI G +GV Q+ NK+ G FTK DE K F+++C +++ + MY ++ ++ R+ E + YH ++ L+ ++P S + E F+ ++ + L I ++ + L +F V++NYR PYHNW HA +VAH ++ ++ TELE L +A LCHD+DHRG +NS+ + + LAALYS+ S +E+HHFSQTV IL EG N+F +L EY + L++IR I+ATDLA + ++ ++ G +L++ H + ++ L+MT+ DL TK W TR A IY EF+ +GD K IG QP MDR++ VP Q+ F + + P Y LS L P +
Sbjct: 194 RVHSVLCLPIL-TAIGDLIAILELHRHLGREPFNLSHQEVATANLAWASVAIHQV---QVCRGLAKQTELNDFLLDVSKTYFDNIVAIDSLLEHIMIYAKNLVNADRCALFQVDHNNKELYSDLFD----IGEENE------GKPVFRKTKEIRFSIEKGIAGQVARTGEVLNIPDAYADPRFNREVDLYTGYTTRNILCMPIVSR-GTVIGVVQMVNKLGGSAFTKTDENNFKMFAVFCALALHCANMYHRIRHSECIYRVTMEKLSYHSICTSEEWKTLTQLTLP--SAIYKEIELFHF---DIAPFEELWPAIFVYMVHNSCGKTSFELEKLCRFTMSVRKNYRRVPYHNWKHAVTVAHCMYAILQK--TTGIFTELERKGLLIACLCHDLDHRGYSNSYLQKFDHPLAALYST--STMEQHHFSQTVSILQLEGHNIFSNLTSGEYEQVLEIIRKAIIATDLALYFGNRKQLAELLSTGALDLNNRAHRDRVIGLMMTACDLCSVTKLWPVTRLTANDIYAEFWAEGDEMKKIGMQPISMMDRDKKDEVPQGQVGFYNAVAIPCYTTLSELFPPS 748
BLAST of Phosphodiesterase vs. Ensembl Zebrafish
Match: pde10a (phosphodiesterase 10A [Source:ZFIN;Acc:ZDB-GENE-040426-1115]) HSP 1 Score: 293.893 bits (751), Expect = 2.344e-85 Identity = 210/600 (35.00%), Postives = 320/600 (53.33%), Query Frame = 1
Query: 922 KIQNALCVPVRHQGTNDVIAIVCLINKSGPAQFTNYDEQVINECFKYTTSVLFTTIAYQNERRLKLQTEK---MLVVAKNIFSRMDNLNELLLMIMQEARNLTQAERCSVFLVDEDSNELVAKVFDGLPTSSDKNERLRLQDGTEIQQPVEIRFPKAQGIAGHVATTGEMLNIKKAYDHPLFYRGVDDETGFKTKNILCFPIQDDCGKTVGVAQLCNKIKGHFFTKMDEEIAKAFSIYCCISITHSLMYKKVEDAQHRSRLANELMMYHMQIPEDDIAWLSTFSIPPVSIFLSDFESFNSIPRNVKDRDTLMACISMFDGIGLISRWRINRRTLTKFIFMVKRNYRDPPYHNWMHAFSVAHFIFICIKNLPLDKQLTELELFALFVASLCHDIDHRGTNNSFQVQSNSILAALYSSEGSVLERHHFSQTVCILNTEGCNVFESLPQKEYXXXXXXXXXXXXXXXXXHHLQIFSKIEKMAQQGYDNLDSENH-NLLLCLLMTSADLSDQTKNWRNTRSVAELIYKEFFRQGDLEKAIGNQPAEQMDRERA-VVPNLQIAFLDGIVSPLYRVLSLLHPQTDCINHTIERTREN---WSKISQ 2697
++ + LC+P+ D+IAI+ L G F ++V + + + Q R L QTE +L V+K F + ++ LL IM A+NL A+RC++F VD ++ EL + +FD ++NE + ++ EIRF +GIAG VA TGE+LNI AY P F R VD TG+ T+NILC PI G +GV Q+ NK+ G FTK DE K F+++C +++ + MY ++ ++ R+ E + YH ++ L+ ++P S + E F+ ++ + L I ++ + L +F V++NYR PYHNW HA +VAH ++ ++ TELE L +A LCHD+DHRG +NS+ + + LAALYS+ S +E+HHFSQTV IL EG N+F +L EY + L++IR I+ATDLA + ++ ++ G +L++ H + ++ L+MT+ DL TK W TR A IY EF+ +GD K IG QP MDR++ VP Q+ F + + P Y LS L P + + +E REN W +I Q
Sbjct: 194 RVHSVLCLPIL-TAIGDLIAILELHRHLGREPFNLSHQEVATANLAWASVAIHQV---QVCRGLAKQTELNDFLLDVSKTYFDNIVAIDSLLEHIMIYAKNLVNADRCALFQVDHNNKELYSDLFD----IGEENEGKPV-----FRKTKEIRFSIEKGIAGQVARTGEVLNIPDAYADPRFNREVDLYTGYTTRNILCMPIVSR-GTVIGVVQMVNKLGGSAFTKTDENNFKMFAVFCALALHCANMYHRIRHSECIYRVTMEKLSYHSICTSEEWKTLTQLTLP--SAIYKEIELFHF---DIAPFEELWPAIFVYMVHNSCGKTSFELEKLCRFTMSVRKNYRRVPYHNWKHAVTVAHCMYAILQK--TTGIFTELERKGLLIACLCHDLDHRGYSNSYLQKFDHPLAALYST--STMEQHHFSQTVSILQ-EGHNIFSNLTSGEYEQVLEIIRKAIIATDLALYFGNRKQLAELLSTGALDLNNRAHRDRVIGLMMTACDLCSVTKLWPVTRLTANDIYAEFWAEGDEMKKIGMQPISMMDRDKKDEVPQGQVGFYNAVAIPCYTTLSELFPPSVPL---LEACRENLSQWERIVQ 766
BLAST of Phosphodiesterase vs. Ensembl Zebrafish
Match: pde10a (phosphodiesterase 10A [Source:ZFIN;Acc:ZDB-GENE-040426-1115]) HSP 1 Score: 293.508 bits (750), Expect = 9.167e-85 Identity = 210/600 (35.00%), Postives = 320/600 (53.33%), Query Frame = 1
Query: 922 KIQNALCVPVRHQGTNDVIAIVCLINKSGPAQFTNYDEQVINECFKYTTSVLFTTIAYQNERRLKLQTEK---MLVVAKNIFSRMDNLNELLLMIMQEARNLTQAERCSVFLVDEDSNELVAKVFDGLPTSSDKNERLRLQDGTEIQQPVEIRFPKAQGIAGHVATTGEMLNIKKAYDHPLFYRGVDDETGFKTKNILCFPIQDDCGKTVGVAQLCNKIKGHFFTKMDEEIAKAFSIYCCISITHSLMYKKVEDAQHRSRLANELMMYHMQIPEDDIAWLSTFSIPPVSIFLSDFESFNSIPRNVKDRDTLMACISMFDGIGLISRWRINRRTLTKFIFMVKRNYRDPPYHNWMHAFSVAHFIFICIKNLPLDKQLTELELFALFVASLCHDIDHRGTNNSFQVQSNSILAALYSSEGSVLERHHFSQTVCILNTEGCNVFESLPQKEYXXXXXXXXXXXXXXXXXHHLQIFSKIEKMAQQGYDNLDSENH-NLLLCLLMTSADLSDQTKNWRNTRSVAELIYKEFFRQGDLEKAIGNQPAEQMDRERA-VVPNLQIAFLDGIVSPLYRVLSLLHPQTDCINHTIERTREN---WSKISQ 2697
++ + LC+P+ D+IAI+ L G F ++V + + + Q R L QTE +L V+K F + ++ LL IM A+NL A+RC++F VD ++ EL + +FD ++NE + ++ EIRF +GIAG VA TGE+LNI AY P F R VD TG+ T+NILC PI G +GV Q+ NK+ G FTK DE K F+++C +++ + MY ++ ++ R+ E + YH ++ L+ ++P S + E F+ ++ + L I ++ + L +F V++NYR PYHNW HA +VAH ++ ++ TELE L +A LCHD+DHRG +NS+ + + LAALYS+ S +E+HHFSQTV IL EG N+F +L EY + L++IR I+ATDLA + ++ ++ G +L++ H + ++ L+MT+ DL TK W TR A IY EF+ +GD K IG QP MDR++ VP Q+ F + + P Y LS L P + + +E REN W +I Q
Sbjct: 194 RVHSVLCLPIL-TAIGDLIAILELHRHLGREPFNLSHQEVATANLAWASVAIHQV---QVCRGLAKQTELNDFLLDVSKTYFDNIVAIDSLLEHIMIYAKNLVNADRCALFQVDHNNKELYSDLFD----IGEENEGKPV-----FRKTKEIRFSIEKGIAGQVARTGEVLNIPDAYADPRFNREVDLYTGYTTRNILCMPIVSR-GTVIGVVQMVNKLGGSAFTKTDENNFKMFAVFCALALHCANMYHRIRHSECIYRVTMEKLSYHSICTSEEWKTLTQLTLP--SAIYKEIELFHF---DIAPFEELWPAIFVYMVHNSCGKTSFELEKLCRFTMSVRKNYRRVPYHNWKHAVTVAHCMYAILQK--TTGIFTELERKGLLIACLCHDLDHRGYSNSYLQKFDHPLAALYST--STMEQHHFSQTVSILQ-EGHNIFSNLTSGEYEQVLEIIRKAIIATDLALYFGNRKQLAELLSTGALDLNNRAHRDRVIGLMMTACDLCSVTKLWPVTRLTANDIYAEFWAEGDEMKKIGMQPISMMDRDKKDEVPQGQVGFYNAVAIPCYTTLSELFPPSVPL---LEACRENLSQWERIVQ 766
BLAST of Phosphodiesterase vs. Ensembl Zebrafish
Match: pde11al (phosphodiesterase 11a, like [Source:ZFIN;Acc:ZDB-GENE-031118-106]) HSP 1 Score: 288.115 bits (736), Expect = 2.646e-82 Identity = 191/602 (31.73%), Postives = 316/602 (52.49%), Query Frame = 1
Query: 922 KIQNALCVPVRHQGTNDVIAIVCLINKSGPAQ-FTNYDEQVINECFKYTTSVLFTTIAYQNERRLKLQTEKMLVVAKNIFSRMDNLNELLLMIMQEARNLTQAERCSVFLVDEDSNELV--AKVFDGLPT--SSDKN---ERLRLQDGTEIQQPVEIRFPKAQGIAGHVATTGEMLNIKKAYDHPLFYRGVDDETGFKTKNILCFPIQDDCGKTVGVAQLCNKIKGHFFTKMDEEIAKAFSIYCCISITHSLMYKKVEDAQHRSRLANELMMYHMQIPEDDIAWLSTFSIPPVSIFLSDFESFNSIPRNVKDRDTLM-ACISMFDGIGLISRWRINRRTLTKFIFMVKRNYRDPPYHNWMHAFSVAHFIFICIKNLPLDKQLTELELFALFVASLCHDIDHRGTNNSFQVQSNSILAALYSSEGSVLERHHFSQTVCILNTEGCNVFESLPQKEYXXXXXXXXXXXXXXXXXHHLQIFSKIEKMAQQG-YDNLDSENHNLLLCLLMTSADLSDQTKNWRNTRSVAELIYKEFFRQGDLEKA-IGNQPAEQMDRERA-VVPNLQIAFLDGIVSPLYRVLSLLHPQTDCINHTIERTRENWSKI 2691
K Q+ LC+ +R+ +VI +V INK+ FT DE+V+ + + + R+ ++ +L V ++F +L +++ IMQ A L Q ERCSV L+++ + +V ++ F+ + S D++ E++ D + IA VA+TG +NI P F D +GF +++LC PI + + +GVAQ+ N++ F D+ + +AF I+C + I +++MY +V+ + +A +++ YH + ++ L IP S D FN D D ++ A + MF +G++ +++I+ L +++ V++NYR YHNW HAF+V+ +FI I + LTE E AL V CHD+DHRGTNN+FQ +S S LA LY + + LE HHF+ V IL +EG N+F +L KEY + L++ IL+TDL + + + G + D E+ ++ +LMT+ DL T+ W ++ VAEL+ EFF QGD E++ + PA DR R +P LQ+ ++DGI PLY L L+ + + I+ R+ W ++
Sbjct: 275 KTQSILCMAIRN-SDGEVIGVVQAINKNPSGTPFTEDDEKVLQMYLPFCGISISNAKLFSESRKEYERSRALLEVVNDLFEEQTDLEKIVRKIMQRALTLLQCERCSVLLLEDIHSPVVKFSQTFELMSPLCSVDRDISMEKVSCSD-----------WLINNSIAELVASTGLPVNISDVCQDPRFDAEADQASGFHIRSVLCVPIWNRTHQIIGVAQILNRLDRKTFNDADQRLFEAFVIFCGLGINNTMMYNQVKKTWAKQSVALDMLSYHATCSKAEVDRLKAAKIPLSSELGIDEFHFNDFSL---DNDAMITASLRMFLELGVVQKFKIDYEVLCRWLLTVRKNYRTVAYHNWRHAFNVSQCMFIMITTAAFQEVLTETETLALMVGCFCHDLDHRGTNNAFQAKSGSALALLYGTSAT-LEHHHFNHAVMILQSEGHNIFANLCSKEYCNMMQLLKQAILSTDLTLYFKKRTTFFDCVLSGQFSWSDEEHRDMFRSMLMTACDLGAVTRPWEISKQVAELVTSEFFEQGDRERSELKLTPAAIFDRNRKDELPVLQLEWIDGICKPLYEALVKLNRKLQPMVDGIDANRKKWEEL 860 HSP 2 Score: 93.5893 bits (231), Expect = 7.217e-19 Identity = 68/210 (32.38%), Postives = 112/210 (53.33%), Query Frame = 1
Query: 1078 FTTIAYQNERRLKLQTEK--MLVVAKNIFSRMDNLNELLLMIMQEARNLTQAERCSVFLVDEDSNE--LVAKVFDGLPTSSDKNERLRLQDGTEIQQPVEIRFPKAQGIAGHVATTGEMLNIKKAYDHPLFYRGVDDETGFKTKNILCFPIQDDCGKTVGVAQLCNK-IKGHFFTKMDEEIAKAFSIYCCISITHSLMYKKVEDAQHRSR 1692
+ + A + RLK E+ L + K+I + +D N L I+ + A+RCS+FLV+ S++ LV+K FD ++ + L D E+Q P +GI G+VA GE +N AY+ F +D TG+KT++ILC I++ G+ +GV Q NK G FT+ DE++ + + +C ISI+++ ++ + RSR
Sbjct: 142 YASSAIDYKYRLKESNEREFFLELVKDISNELDMTN-LSYKILINVCIMVNADRCSLFLVEGPSHKRTLVSKFFDVHSGTTVRPSSSTL-DSNEVQ------VPWGKGIIGYVAEHGETVNTPNAYEDHRFSDEIDKLTGYKTQSILCMAIRNSDGEVIGVVQAINKNPSGTPFTEDDEKVLQMYLPFCGISISNAKLFSESRKEYERSR 343
BLAST of Phosphodiesterase vs. Ensembl Xenopus
Match: pde2a (phosphodiesterase 2A [Source:NCBI gene;Acc:780063]) HSP 1 Score: 342.428 bits (877), Expect = 2.846e-105 Identity = 179/376 (47.61%), Postives = 249/376 (66.22%), Query Frame = 1
Query: 610 QILELCGSLFDQDAGKLQKKVLSYLIQNTSAETGFLLLVCMDTVELLCQVIGQVIQEDPINFDAEENGIFDKVLKSKTGINLGCLTEAQLREISEIMNASKQETKIQNALCVPVRHQGTNDVIAIVCLINKSGPAQFTNYDEQVINECFKYTTSVLFTTIAYQNERRLKLQTEKMLVVAKNIFSRMDNLNELLLMIMQEARNLTQAERCSVFLVDEDSNELVAKVFDGLPTSSDKNERLRLQDGTEIQQPVEIRFPKAQGIAGHVATTGEMLNIKKAYDHPLFYRGVDDETGFKTKNILCFPIQDDCGKTVGVAQLCNKIKGHFFTKMDEEIAKAFSIYCCISITHSLMYKKVEDAQHRSRLANELMMYHMQIPED 1737
+IL+LCG L+D DA LQ KV+ YL Q T + LLLV D+ +L CQV+G + E+ I+F G +V+ K I L ++ + R+++ ++ ++ + LCVPV + T+ V+A+ C NK G ++T DE I CF YT++VL +T+A+Q E++LK + + + V K++ + +D+++ LL I+ EARNL+ AE CSVFL++ S+ELVAKVFDG G + EIR P QGIAGHVATTG++LNIK AY HPLFYRGVDD TGF+T+NILCFPI+++ + +GVA+L NKI G FTK DE++A AFSIYC ISI HSL+YK+V +AQ RS LANE+MMYHM+I D
Sbjct: 230 KILQLCGELYDLDAASLQIKVIHYLEQQTQSPCCCLLLVSEDSHQLFCQVVGGKVLEEEISFPLT-FGHLGQVVDKKKSITLQDISSEEHRQLNNMLG-----FEVHSMLCVPVISRATSQVVALACAFNKQG-GKYTEVDEHKIQHCFCYTSTVLTSTLAFQKEQKLKCECQSLRRVRKSLITYLDDVSVLLQEIITEARNLSNAEICSVFLLERQSHELVAKVFDG---------------GVVDDESYEIRIPADQGIAGHVATTGQILNIKDAYSHPLFYRGVDDSTGFRTRNILCFPIKNESNEVIGVAELVNKINGPGFTKFDEDLATAFSIYCGISIAHSLLYKQVREAQFRSHLANEMMMYHMKICRD 583
BLAST of Phosphodiesterase vs. Ensembl Xenopus
Match: pde2a (phosphodiesterase 2A [Source:NCBI gene;Acc:780063]) HSP 1 Score: 328.176 bits (840), Expect = 6.864e-100 Identity = 175/373 (46.92%), Postives = 241/373 (64.61%), Query Frame = 1
Query: 610 QILELCGSLFDQDAGKLQKKVLSYLIQNTSAETGFLLLVCMDTVELLCQVIGQVIQEDPINFDAEENGIFDKVLKSKTGINLGCLTEAQLREISEIMNASKQETKIQNALCVPVRHQGTNDVIAIVCLINKSGPAQFTNYDEQVINECFKYTTSVLFTTIAYQNERRLKLQTEKMLVVAKNIFSRMDNLNELLLMIMQEARNLTQAERCSVFLVDEDSNELVAKVFDGLPTSSDKNERLRLQDGTEIQQPVEIRFPKAQGIAGHVATTGEMLNIKKAYDHPLFYRGVDDETGFKTKNILCFPIQDDCGKTVGVAQLCNKIKGHFFTKMDEEIAKAFSIYCCISITHSLMYKKVEDAQHRSRLANELMMYHMQI 1728
+IL+LCG L+D DA LQ KV+ YL Q T + LLLV D+ +L CQV+G + E+ I+F G +V+ K I L ++ + R+++ ++ ++ + LCVPV + T+ V+A+ C NK G ++T DE I CF YT++VL +T+A+Q E++LK + + D+++ LL I+ EARNL+ AE CSVFL++ S+ELVAKVFDG G + EIR P QGIAGHVATTG++LNIK AY HPLFYRGVDD TGF+T+NILCFPI+++ + +GVA+L NKI G FTK DE++A AFSIYC ISI HSL+YK+V +AQ RS LANE+MMYHM++
Sbjct: 228 KILQLCGELYDLDAASLQIKVIHYLEQQTQSPCCCLLLVSEDSHQLFCQVVGGKVLEEEISFPLT-FGHLGQVVDKKKSITLQDISSEEHRQLNNMLG-----FEVHSMLCVPVISRATSQVVALACAFNKQG-GKYTEVDEHKIQHCFCYTSTVLTSTLAFQKEQKLKCECQ---------VGPTDDVSVLLQEIITEARNLSNAEICSVFLLERQSHELVAKVFDG---------------GVVDDESYEIRIPADQGIAGHVATTGQILNIKDAYSHPLFYRGVDDSTGFRTRNILCFPIKNESNEVIGVAELVNKINGPGFTKFDEDLATAFSIYCGISIAHSLLYKQVREAQFRSHLANEMMMYHMKV 569
BLAST of Phosphodiesterase vs. Ensembl Xenopus
Match: PDE10A (phosphodiesterase 10A [Source:NCBI gene;Acc:100485841]) HSP 1 Score: 302.368 bits (773), Expect = 2.647e-88 Identity = 209/603 (34.66%), Postives = 318/603 (52.74%), Query Frame = 1
Query: 919 TKIQNALCVPVRHQGTNDVIAIVCLINKSGPAQFTNYDEQVINECFKYTTSVLFTTIAYQNERRLKLQTEK---MLVVAKNIFSRMDNLNELLLMIMQEARNLTQAERCSVFLVDEDSNELVAKVFDGLPTSSDKNERLRLQDGTEIQQPVEIRFPKAQGIAGHVATTGEMLNIKKAYDHPLFYRGVDDETGFKTKNILCFPIQDDCGKTVGVAQLCNKIKGHFFTKMDEEIAKAFSIYCCISITHSLMYKKVEDAQHRSRLANELMMYHMQIPEDDIAWLSTFSIP-----PVSIFLSDFESFNSIPRNVKDRDTLMACISMFDGIGLISRWRINRRTLTKFIFMVKRNYRDPPYHNWMHAFSVAHFIFICIKNLPLDKQLTELELFALFVASLCHDIDHRGTNNSFQVQSNSILAALYSSEGSVLERHHFSQTVCILNTEGCNVFESLPQKEYXXXXXXXXXXXXXXXXXHHLQIFSKIEKMAQQGYDNLDSENH-NLLLCLLMTSADLSDQTKNWRNTRSVAELIYKEFFRQGDLEKAIGNQPAEQMDRERA-VVPNLQIAFLDGIVSPLYRVLSLLHPQTDCINHTIERTRENWSKISQ 2697
T+IQ+ LC+P+ D+I I+ L G F +QV + + + Q R L QTE +L V+K F + ++ LL IM A+NL A+RC++F VD + EL + +FD D+ + + ++ EIRF +GIAG VA TGE+LNI AY P F R VD TG+ T+NILC PI G +GV Q+ NK+ G F+K DE K F+++C +++ + MY ++ ++ R+ E + YH D+ L ++P + ++ D + F + L I ++ + L +F VK+NYR PYHNW HA +V+H +++ ++N + T+LE L VA LCHD+DHRG NS+ + + LAALYS+ S +E+HHFSQTV IL EG N+F +L EY + L++IR I+ATDLA + +E + Q G NL+++ H + L+ L+MT+ DL TK W TR +A+ IY EF+ +GD K +G P MDR++ +P Q+ F + + P Y LS + P T + + W K+S+
Sbjct: 191 TRIQSVLCLPIV-TAIGDLIGILELYRHWGKGSFRLCHQQVATANLAWASVAIHQV---QVCRGLAKQTELNDFLLDVSKTYFDNIVAIDSLLEHIMIYAKNLVNADRCALFQVDHKNKELYSDLFD--IGEEDEGKPV-------FKKTKEIRFSIEKGIAGQVARTGEVLNIPDAYADPRFNREVDVYTGYTTRNILCMPIVIR-GSVIGVVQMVNKLSGSAFSKTDENNFKMFAVFCALALHCANMYHRIRHSECIYRVTLEKLSYHSICTSDEWQNLMNCTLPVSLCREIELYHFDIQPF----------EDLWPAIYVYMIHQSCGKNCFELEKLCRFTMSVKKNYRRVPYHNWKHAVTVSHCMYVILQN--NQEIFTDLERKGLLVACLCHDLDHRGYTNSYLQKFDHPLAALYST--STMEQHHFSQTVSILQLEGHNIFSNLSSNEYEQVLEIIRKAIIATDLALYFGNRKHLEDLHQMGALNLNNQAHRDRLIGLMMTACDLCSVTKLWPVTRLIADDIYAEFWTEGDEMKRLGISPIPMMDRDKQDEIPQGQMGFYNAVAVPCYTTLSEIFPSTRPLLQACKENLSQWEKVSR 765
BLAST of Phosphodiesterase vs. Ensembl Xenopus
Match: ENSXETT00000053056.1 (phosphodiesterase 11A [Source:NCBI gene;Acc:100379882]) HSP 1 Score: 299.286 bits (765), Expect = 2.525e-86 Identity = 191/613 (31.16%), Postives = 329/613 (53.67%), Query Frame = 1
Query: 922 KIQNALCVPVRHQGTNDVIAIVCLINKS-GPAQFTNYDEQVINECFKYTTSVLFTTIAYQNERRLKLQTEKMLVVAKNIFSRMDNLNELLLMIMQEARNLTQAERCSVFLVDEDSNELV--AKVFDGLPTSSDKNERLRLQDGTEIQQPVEIRFPKAQGIAGHVATTGEMLNIKKAYDHPLFYRGVDDETGFKTKNILCFPIQDDCGKTVGVAQLCNKIKGHFFTKMDEEIAKAFSIYCCISITHSLMYKKVEDAQHRSRLANELMMYHMQIPEDDIAWLSTFSIPPVS-IFLSD--FESFNSIPRNVKDRDTLM-ACISMFDGIGLISRWRINRRTLTKFIFMVKRNYRDPPYHNWMHAFSVAHFIFICIKNLPLDKQLTELELFALFVASLCHDIDHRGTNNSFQVQSNSILAALYSSEGSVLERHHFSQTVCILNTEGCNVFESLPQKEYXXXXXXXXXXXXXXXXXHHLQIFSKIEKMAQQGYDNLDSENHNLLL-CLLMTSADLSDQTKNWRNTRSVAELIYKEFFRQGDLEK-AIGNQPAEQMDRERA-VVPNLQIAFLDGIVSPLYRVLSLLHPQTDCINHTIERTRENWSKISQKVASHEIKGNS 2730
K ++ LC+P+R ++I + INK+ G A F DE+V+ + + + R+ ++ +L V ++F +L +++ IM A+NL + ERCSV L+++ + +V K F+ L + +D E + + IA VA+TG +NI AY P F D +GF +++LC PI + + +GVAQ+ N+I G F D+ + +AF I+C + I +++MY +V+ + + +A +++ YH + ++ +IP VS + ++D F+ F D D ++ A + MF +G++ +++I+ TL +++ +++NYR YHNW HAF+V +F + + L++ E AL V LCHD+DHRGTNN+FQ +S S L+ LY + + LE HHF+ V IL +EG N+F +L +EY + L++ ILATD+ H + ++ ++ +G N + ++H ++ +LMT+ DL TK W +R VAEL+ EFF QGD E+ + P+ DR R +P LQ+ ++D I PLY L ++ + + ++ R W ++ H +GNS
Sbjct: 274 KTKSLLCMPIR-SSDGEIIGVAQAINKTPGGAPFIEDDEKVMQMYLPFCGIAISNAQLFAASRKEYDRSRALLEVVNDLFEEQTDLEKVVKKIMHRAQNLLKCERCSVLLLEDIESPVVKFTKSFELLSPKCSADTENSFKDSVEKSSYSD--WLVNNSIAELVASTGLPVNISDAYQDPRFDVEADQFSGFHIRSVLCVPIWNSSHQIIGVAQVLNRIDGKPFDDADQRLFEAFVIFCGLGINNTIMYDQVKKSWAKQSVALDVLSYHATCSKAEVDKFKAANIPLVSELSIADIHFDDF------CLDVDAMISAALRMFMELGMVQKFKIDYETLCRWLLTIRKNYRMVLYHNWRHAFNVCQLMFAMLTTAGFQEVLSDTETLALIVGCLCHDLDHRGTNNAFQAKSGSALSQLYGTSAT-LEHHHFNHAVMILQSEGHNIFANLSSQEYSDLMQLLKQSILATDITLHFERRNEFFELVNKGDYNWNVKSHRVIFRSMLMTACDLGAATKPWEISRQVAELVTSEFFEQGDRERLELKMTPSAIFDRNRKDELPRLQLEWIDNICFPLYESLVKINGKLKPMLDSVTTNRGKWEEL------HRKQGNS 870 HSP 2 Score: 97.4413 bits (241), Expect = 6.839e-20 Identity = 62/183 (33.88%), Postives = 96/183 (52.46%), Query Frame = 1
Query: 1171 NLNELLLMIMQEARNLTQAERCSVFLVDEDSNE--LVAKVFDG------LPTSSDKNERLRLQDGTEIQQPVEIRFPKAQGIAGHVATTGEMLNIKKAYDHPLFYRGVDDETGFKTKNILCFPIQDDCGKTVGVAQLCNKIKGHF-FTKMDEEIAKAFSIYCCISITHSLMYKKVEDAQHRSR 1692
NL L I+ + A+RCS+FLV+ +N+ LV+K FD LP+ S +N E++ P +GI G+VA GE +NI AY F +D TG+KTK++LC PI+ G+ +GVAQ NK G F + DE++ + + +C I+I+++ ++ RSR
Sbjct: 173 NLTSLCYKILIFVCIMVDADRCSLFLVEGTANKKSLVSKFFDVHAGTTLLPSCSTENSN-------------EVQVPWGKGIIGYVAEHGETVNIPDAYQDRRFSDEIDKLTGYKTKSLLCMPIRSSDGEIIGVAQAINKTPGGAPFIEDDEKVMQMYLPFCGIAISNAQLFAASRKEYDRSR 342
BLAST of Phosphodiesterase vs. Ensembl Xenopus
Match: PDE10A (phosphodiesterase 10A [Source:NCBI gene;Acc:100485841]) HSP 1 Score: 287.345 bits (734), Expect = 8.991e-84 Identity = 204/583 (34.99%), Postives = 305/583 (52.32%), Query Frame = 1
Query: 919 TKIQNALCVPVRHQGTNDVIAIVCLINKSGPAQFTNYDEQVINECFKYTTSVLFTTIAYQNERRLKLQTE--KMLVVAKNIFSRMDNLNELLLMIMQEARNLTQAERCSVFLVDEDSNELVAKVFDGLPTSSDKNERLRLQDGTEIQQPVEIRFPKAQGIAGHVATTGEMLNIKKAYDHPLFYRGVDDETGFKTKNILCFPIQDDCGKTVGVAQLCNKIKGHFFTKMDEEIAKAFSIYCCISITHSLMYKKVEDAQHRSRLANELMMYHMQIPEDDIAWLSTFSIP-----PVSIFLSDFESFNSIPRNVKDRDTLMACISMFDGIGLISRWRINRRTLTKFIFMVKRNYRDPPYHNWMHAFSVAHFIFICIKNLPLDKQLTELELFALFVASLCHDIDHRGTNNSFQVQSNSILAALYSSEGSVLERHHFSQTVCILNTEGCNVFESLPQKEYXXXXXXXXXXXXXXXXXHHLQIFSKIEKMAQQGYDNLDSENH-NLLLCLLMTSADLSDQTKNWRNTRSVAELIYKEFFRQGDLEKAIGNQPAEQMDRERA-VVPNLQIAFLDGIVSPLYRVLSLLHPQT 2640
T+IQ+ LC+P+ D+I I+ L G F +QV + + + Q R L QTE L+ N F NE L I A+NL A+RC++F VD + EL + +FD D+ + + ++ EIRF +GIAG VA TGE+LNI AY P F R VD TG+ T+NILC PI G +GV Q+ NK+ G F+K DE K F+++C +++ + MY ++ ++ R+ E + YH D+ L ++P + ++ D + F + + +C + L +F VK+NYR PYHNW HA +V+H +++ ++N + T+LE L VA LCHD+DHRG NS+ + + LAALYS+ S +E+HHFSQTV IL EG N+F +L EY + L++IR I+ATDLA + +E + Q G NL+++ H + L+ L+MT+ DL TK W TR +A+ IY EF+ +GD K +G P MDR++ +P Q+ F + + P Y LS + P T
Sbjct: 133 TRIQSVLCLPIV-TAIGDLIGILELYRHWGKGSFRLCHQQVATANLAWASVAIHQV---QVCRGLAKQTELNDFLLDVSNHFD-----NESFLQIY--AKNLVNADRCALFQVDHKNKELYSDLFD--IGEEDEGKPV-------FKKTKEIRFSIEKGIAGQVARTGEVLNIPDAYADPRFNREVDVYTGYTTRNILCMPIVIR-GSVIGVVQMVNKLSGSAFSKTDENNFKMFAVFCALALHCANMYHRIRHSECIYRVTLEKLSYHSICTSDEWQNLMNCTLPVSLCREIELYHFDIQPFEDLWPAIYVYMIHQSC----------GKNCFELEKLCRFTMSVKKNYRRVPYHNWKHAVTVSHCMYVILQN--NQEIFTDLERKGLLVACLCHDLDHRGYTNSYLQKFDHPLAALYST--STMEQHHFSQTVSILQLEGHNIFSNLSSNEYEQVLEIIRKAIIATDLALYFGNRKHLEDLHQMGALNLNNQAHRDRLIGLMMTACDLCSVTKLWPVTRLIADDIYAEFWTEGDEMKRLGISPIPMMDRDKQDEIPQGQMGFYNAVAVPCYTTLSEIFPST 680
BLAST of Phosphodiesterase vs. Ensembl Mouse
Match: Gm45837 (predicted gene 45837 [Source:MGI Symbol;Acc:MGI:5804952]) HSP 1 Score: 719.924 bits (1857), Expect = 0.000e+0 Identity = 371/725 (51.17%), Postives = 502/725 (69.24%), Query Frame = 1
Query: 586 KIISNQINQILELCGSLFDQDAGKLQKKVLSYLIQNTSAETGFLLLVCMDTVELLCQVIGQVIQEDPINFDAEENGIFDKVLKSKTGINLGCLTEAQLREISEIMNASKQETKIQNALCVPVRHQGTNDVIAIVCLINKSGPAQFTNYDEQVINECFKYTTSVLFTTIAYQNERRLKLQTEKMLVVAKNIFSRMDNLNELLLMIMQEARNLTQAERCSVFLVDEDSNELVAKVFDGLPTSSDKNERLRLQDGTEIQQPVEIRFPKAQGIAGHVATTGEMLNIKKAYDHPLFYRGVDDETGFKTKNILCFPIQDDCGKTVGVAQLCNKIKGHFFTKMDEEIAKAFSIYCCISITHSLMYKKVEDAQHRSRLANELMMYHMQIPEDDIAWLSTFSIPPVSIFLSDFESFNSIPRNVKDRDTLMACISMFDGIGLISRWRINRRTLTKFIFMVKRNYRDPPYHNWMHAFSVAHFIFICIKNLPLDKQLTELELFALFVASLCHDIDHRGTNNSFQVQSNSILAALYSSEGSVLERHHFSQTVCILNTEGCNVFESLPQKEYXXXXXXXXXXXXXXXXXHHLQIFSKIEKMAQQGYDNLDSENHNLLLCLLMTSADLSDQTKNWRNTRSVAELIYKEFFRQGDLEKAIGNQPAEQMDRERAVVPNLQIAFLDGIVSPLYRVLSLLHPQTDCINHTIERTRENWSKISQKVASHEIKGNSEEIFRNKLVE 2760
K ++ +IL+LCG LFD DA LQ KVL YL Q T A LLLV D ++L C+VIG + + ++F G +V++ K I L LT ++++ ++ ++Q LCVPV + T+ V+A+ C NK G FT+ DE VI CF YT +VL +T+A+Q E++LK + + +L VAKN+F+ +D+++ LL I+ EARNL+ AE CSVFL+D+ NELVAKVFDG G + EIR P QGIAGHVATTG++LNI AY HPLFYRGVDD TGF+T+NILCFPI+++ + +GVA+L NKI G +F+K DE++A AFSIYC ISI HSL+YKKV +AQ+RS LANE+MMYHM++ +D+ L I PV+ S+F +F PR++ + DT MA +SM + I+ ++I+ TL +F MVK+ YRDPPYHNWMHAFSV+HF ++ KNL L L ++E+FALF++ +CHD+DHRGTNNSFQV S S+LAALYSSEGSV+ERHHF+Q + ILNT GCN+F+ +K+Y R LDL+RDIILATDLAHHL+IF ++KMA+ GYD + ++H LLLCLLMTS DLSDQTK W+ TR +AELIYKEFF QGDLEKA+GN+P E MDRE+A +P LQI+F++ I P+Y++L L P+ + + RE+W+K+S K + N+ F ++ E
Sbjct: 241 KGYTDHDRKILQLCGELFDLDATSLQLKVLQYLQQETQATHCCLLLVSEDNLQLSCKVIGDKVLGEEVSFPLT-MGRLGQVVEDKQCIQLKDLTSDDVQQLQNMLGC-----ELQAMLCVPVISRATDQVVALACAFNKLGGDFFTDEDEHVIQHCFHYTGTVLTSTLAFQKEQKLKCECQALLQVAKNLFTHLDDVSVLLQEIITEARNLSNAEICSVFLLDQ--NELVAKVFDG---------------GVVDDESYEIRIPADQGIAGHVATTGQILNIPDAYAHPLFYRGVDDSTGFRTRNILCFPIKNENQEVIGVAELVNKINGPWFSKFDEDLATAFSIYCGISIAHSLLYKKVNEAQYRSHLANEMMMYHMKVSDDEYTKLLHDGIQPVAAIDSNFANFTYTPRSLPEDDTSMAILSMLQDMNFINNYKIDCPTLARFCLMVKKGYRDPPYHNWMHAFSVSHFCYLLYKNLELSNYLEDIEIFALFISCMCHDLDHRGTNNSFQVASKSVLAALYSSEGSVMERHHFAQAIAILNTHGCNIFDHFSRKDYQRMLDLMRDIILATDLAHHLRIFKDLQKMAEVGYDRNNRQHHRLLLCLLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEKAMGNRPMEMMDREKAYIPELQISFMEHIAMPIYKLLQDLFPKAAELYERVASNREHWTKVSHKFTIRGLPSNNSLDFLDEEYE 942
BLAST of Phosphodiesterase vs. Ensembl Mouse
Match: Pde2a (phosphodiesterase 2A, cGMP-stimulated [Source:MGI Symbol;Acc:MGI:2446107]) HSP 1 Score: 719.153 bits (1855), Expect = 0.000e+0 Identity = 371/725 (51.17%), Postives = 502/725 (69.24%), Query Frame = 1
Query: 586 KIISNQINQILELCGSLFDQDAGKLQKKVLSYLIQNTSAETGFLLLVCMDTVELLCQVIGQVIQEDPINFDAEENGIFDKVLKSKTGINLGCLTEAQLREISEIMNASKQETKIQNALCVPVRHQGTNDVIAIVCLINKSGPAQFTNYDEQVINECFKYTTSVLFTTIAYQNERRLKLQTEKMLVVAKNIFSRMDNLNELLLMIMQEARNLTQAERCSVFLVDEDSNELVAKVFDGLPTSSDKNERLRLQDGTEIQQPVEIRFPKAQGIAGHVATTGEMLNIKKAYDHPLFYRGVDDETGFKTKNILCFPIQDDCGKTVGVAQLCNKIKGHFFTKMDEEIAKAFSIYCCISITHSLMYKKVEDAQHRSRLANELMMYHMQIPEDDIAWLSTFSIPPVSIFLSDFESFNSIPRNVKDRDTLMACISMFDGIGLISRWRINRRTLTKFIFMVKRNYRDPPYHNWMHAFSVAHFIFICIKNLPLDKQLTELELFALFVASLCHDIDHRGTNNSFQVQSNSILAALYSSEGSVLERHHFSQTVCILNTEGCNVFESLPQKEYXXXXXXXXXXXXXXXXXHHLQIFSKIEKMAQQGYDNLDSENHNLLLCLLMTSADLSDQTKNWRNTRSVAELIYKEFFRQGDLEKAIGNQPAEQMDRERAVVPNLQIAFLDGIVSPLYRVLSLLHPQTDCINHTIERTRENWSKISQKVASHEIKGNSEEIFRNKLVE 2760
K ++ +IL+LCG LFD DA LQ KVL YL Q T A LLLV D ++L C+VIG + + ++F G +V++ K I L LT ++++ ++ ++Q LCVPV + T+ V+A+ C NK G FT+ DE VI CF YT +VL +T+A+Q E++LK + + +L VAKN+F+ +D+++ LL I+ EARNL+ AE CSVFL+D+ NELVAKVFDG G + EIR P QGIAGHVATTG++LNI AY HPLFYRGVDD TGF+T+NILCFPI+++ + +GVA+L NKI G +F+K DE++A AFSIYC ISI HSL+YKKV +AQ+RS LANE+MMYHM++ +D+ L I PV+ S+F +F PR++ + DT MA +SM + I+ ++I+ TL +F MVK+ YRDPPYHNWMHAFSV+HF ++ KNL L L ++E+FALF++ +CHD+DHRGTNNSFQV S S+LAALYSSEGSV+ERHHF+Q + ILNT GCN+F+ +K+Y R LDL+RDIILATDLAHHL+IF ++KMA+ GYD + ++H LLLCLLMTS DLSDQTK W+ TR +AELIYKEFF QGDLEKA+GN+P E MDRE+A +P LQI+F++ I P+Y++L L P+ + + RE+W+K+S K + N+ F ++ E
Sbjct: 225 KGYTDHDRKILQLCGELFDLDATSLQLKVLQYLQQETQATHCCLLLVSEDNLQLSCKVIGDKVLGEEVSFPLT-MGRLGQVVEDKQCIQLKDLTSDDVQQLQNMLGC-----ELQAMLCVPVISRATDQVVALACAFNKLGGDFFTDEDEHVIQHCFHYTGTVLTSTLAFQKEQKLKCECQALLQVAKNLFTHLDDVSVLLQEIITEARNLSNAEICSVFLLDQ--NELVAKVFDG---------------GVVDDESYEIRIPADQGIAGHVATTGQILNIPDAYAHPLFYRGVDDSTGFRTRNILCFPIKNENQEVIGVAELVNKINGPWFSKFDEDLATAFSIYCGISIAHSLLYKKVNEAQYRSHLANEMMMYHMKVSDDEYTKLLHDGIQPVAAIDSNFANFTYTPRSLPEDDTSMAILSMLQDMNFINNYKIDCPTLARFCLMVKKGYRDPPYHNWMHAFSVSHFCYLLYKNLELSNYLEDIEIFALFISCMCHDLDHRGTNNSFQVASKSVLAALYSSEGSVMERHHFAQAIAILNTHGCNIFDHFSRKDYQRMLDLMRDIILATDLAHHLRIFKDLQKMAEVGYDRNNRQHHRLLLCLLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEKAMGNRPMEMMDREKAYIPELQISFMEHIAMPIYKLLQDLFPKAAELYERVASNREHWTKVSHKFTIRGLPSNNSLDFLDEEYE 926
BLAST of Phosphodiesterase vs. Ensembl Mouse
Match: Pde2a (phosphodiesterase 2A, cGMP-stimulated [Source:MGI Symbol;Acc:MGI:2446107]) HSP 1 Score: 718.383 bits (1853), Expect = 0.000e+0 Identity = 371/725 (51.17%), Postives = 502/725 (69.24%), Query Frame = 1
Query: 586 KIISNQINQILELCGSLFDQDAGKLQKKVLSYLIQNTSAETGFLLLVCMDTVELLCQVIGQVIQEDPINFDAEENGIFDKVLKSKTGINLGCLTEAQLREISEIMNASKQETKIQNALCVPVRHQGTNDVIAIVCLINKSGPAQFTNYDEQVINECFKYTTSVLFTTIAYQNERRLKLQTEKMLVVAKNIFSRMDNLNELLLMIMQEARNLTQAERCSVFLVDEDSNELVAKVFDGLPTSSDKNERLRLQDGTEIQQPVEIRFPKAQGIAGHVATTGEMLNIKKAYDHPLFYRGVDDETGFKTKNILCFPIQDDCGKTVGVAQLCNKIKGHFFTKMDEEIAKAFSIYCCISITHSLMYKKVEDAQHRSRLANELMMYHMQIPEDDIAWLSTFSIPPVSIFLSDFESFNSIPRNVKDRDTLMACISMFDGIGLISRWRINRRTLTKFIFMVKRNYRDPPYHNWMHAFSVAHFIFICIKNLPLDKQLTELELFALFVASLCHDIDHRGTNNSFQVQSNSILAALYSSEGSVLERHHFSQTVCILNTEGCNVFESLPQKEYXXXXXXXXXXXXXXXXXHHLQIFSKIEKMAQQGYDNLDSENHNLLLCLLMTSADLSDQTKNWRNTRSVAELIYKEFFRQGDLEKAIGNQPAEQMDRERAVVPNLQIAFLDGIVSPLYRVLSLLHPQTDCINHTIERTRENWSKISQKVASHEIKGNSEEIFRNKLVE 2760
K ++ +IL+LCG LFD DA LQ KVL YL Q T A LLLV D ++L C+VIG + + ++F G +V++ K I L LT ++++ ++ ++Q LCVPV + T+ V+A+ C NK G FT+ DE VI CF YT +VL +T+A+Q E++LK + + +L VAKN+F+ +D+++ LL I+ EARNL+ AE CSVFL+D+ NELVAKVFDG G + EIR P QGIAGHVATTG++LNI AY HPLFYRGVDD TGF+T+NILCFPI+++ + +GVA+L NKI G +F+K DE++A AFSIYC ISI HSL+YKKV +AQ+RS LANE+MMYHM++ +D+ L I PV+ S+F +F PR++ + DT MA +SM + I+ ++I+ TL +F MVK+ YRDPPYHNWMHAFSV+HF ++ KNL L L ++E+FALF++ +CHD+DHRGTNNSFQV S S+LAALYSSEGSV+ERHHF+Q + ILNT GCN+F+ +K+Y R LDL+RDIILATDLAHHL+IF ++KMA+ GYD + ++H LLLCLLMTS DLSDQTK W+ TR +AELIYKEFF QGDLEKA+GN+P E MDRE+A +P LQI+F++ I P+Y++L L P+ + + RE+W+K+S K + N+ F ++ E
Sbjct: 215 KGYTDHDRKILQLCGELFDLDATSLQLKVLQYLQQETQATHCCLLLVSEDNLQLSCKVIGDKVLGEEVSFPLT-MGRLGQVVEDKQCIQLKDLTSDDVQQLQNMLGC-----ELQAMLCVPVISRATDQVVALACAFNKLGGDFFTDEDEHVIQHCFHYTGTVLTSTLAFQKEQKLKCECQALLQVAKNLFTHLDDVSVLLQEIITEARNLSNAEICSVFLLDQ--NELVAKVFDG---------------GVVDDESYEIRIPADQGIAGHVATTGQILNIPDAYAHPLFYRGVDDSTGFRTRNILCFPIKNENQEVIGVAELVNKINGPWFSKFDEDLATAFSIYCGISIAHSLLYKKVNEAQYRSHLANEMMMYHMKVSDDEYTKLLHDGIQPVAAIDSNFANFTYTPRSLPEDDTSMAILSMLQDMNFINNYKIDCPTLARFCLMVKKGYRDPPYHNWMHAFSVSHFCYLLYKNLELSNYLEDIEIFALFISCMCHDLDHRGTNNSFQVASKSVLAALYSSEGSVMERHHFAQAIAILNTHGCNIFDHFSRKDYQRMLDLMRDIILATDLAHHLRIFKDLQKMAEVGYDRNNRQHHRLLLCLLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEKAMGNRPMEMMDREKAYIPELQISFMEHIAMPIYKLLQDLFPKAAELYERVASNREHWTKVSHKFTIRGLPSNNSLDFLDEEYE 916
BLAST of Phosphodiesterase vs. Ensembl Mouse
Match: Pde2a (phosphodiesterase 2A, cGMP-stimulated [Source:MGI Symbol;Acc:MGI:2446107]) HSP 1 Score: 718.383 bits (1853), Expect = 0.000e+0 Identity = 371/725 (51.17%), Postives = 502/725 (69.24%), Query Frame = 1
Query: 586 KIISNQINQILELCGSLFDQDAGKLQKKVLSYLIQNTSAETGFLLLVCMDTVELLCQVIGQVIQEDPINFDAEENGIFDKVLKSKTGINLGCLTEAQLREISEIMNASKQETKIQNALCVPVRHQGTNDVIAIVCLINKSGPAQFTNYDEQVINECFKYTTSVLFTTIAYQNERRLKLQTEKMLVVAKNIFSRMDNLNELLLMIMQEARNLTQAERCSVFLVDEDSNELVAKVFDGLPTSSDKNERLRLQDGTEIQQPVEIRFPKAQGIAGHVATTGEMLNIKKAYDHPLFYRGVDDETGFKTKNILCFPIQDDCGKTVGVAQLCNKIKGHFFTKMDEEIAKAFSIYCCISITHSLMYKKVEDAQHRSRLANELMMYHMQIPEDDIAWLSTFSIPPVSIFLSDFESFNSIPRNVKDRDTLMACISMFDGIGLISRWRINRRTLTKFIFMVKRNYRDPPYHNWMHAFSVAHFIFICIKNLPLDKQLTELELFALFVASLCHDIDHRGTNNSFQVQSNSILAALYSSEGSVLERHHFSQTVCILNTEGCNVFESLPQKEYXXXXXXXXXXXXXXXXXHHLQIFSKIEKMAQQGYDNLDSENHNLLLCLLMTSADLSDQTKNWRNTRSVAELIYKEFFRQGDLEKAIGNQPAEQMDRERAVVPNLQIAFLDGIVSPLYRVLSLLHPQTDCINHTIERTRENWSKISQKVASHEIKGNSEEIFRNKLVE 2760
K ++ +IL+LCG LFD DA LQ KVL YL Q T A LLLV D ++L C+VIG + + ++F G +V++ K I L LT ++++ ++ ++Q LCVPV + T+ V+A+ C NK G FT+ DE VI CF YT +VL +T+A+Q E++LK + + +L VAKN+F+ +D+++ LL I+ EARNL+ AE CSVFL+D+ NELVAKVFDG G + EIR P QGIAGHVATTG++LNI AY HPLFYRGVDD TGF+T+NILCFPI+++ + +GVA+L NKI G +F+K DE++A AFSIYC ISI HSL+YKKV +AQ+RS LANE+MMYHM++ +D+ L I PV+ S+F +F PR++ + DT MA +SM + I+ ++I+ TL +F MVK+ YRDPPYHNWMHAFSV+HF ++ KNL L L ++E+FALF++ +CHD+DHRGTNNSFQV S S+LAALYSSEGSV+ERHHF+Q + ILNT GCN+F+ +K+Y R LDL+RDIILATDLAHHL+IF ++KMA+ GYD + ++H LLLCLLMTS DLSDQTK W+ TR +AELIYKEFF QGDLEKA+GN+P E MDRE+A +P LQI+F++ I P+Y++L L P+ + + RE+W+K+S K + N+ F ++ E
Sbjct: 215 KGYTDHDRKILQLCGELFDLDATSLQLKVLQYLQQETQATHCCLLLVSEDNLQLSCKVIGDKVLGEEVSFPLT-MGRLGQVVEDKQCIQLKDLTSDDVQQLQNMLGC-----ELQAMLCVPVISRATDQVVALACAFNKLGGDFFTDEDEHVIQHCFHYTGTVLTSTLAFQKEQKLKCECQALLQVAKNLFTHLDDVSVLLQEIITEARNLSNAEICSVFLLDQ--NELVAKVFDG---------------GVVDDESYEIRIPADQGIAGHVATTGQILNIPDAYAHPLFYRGVDDSTGFRTRNILCFPIKNENQEVIGVAELVNKINGPWFSKFDEDLATAFSIYCGISIAHSLLYKKVNEAQYRSHLANEMMMYHMKVSDDEYTKLLHDGIQPVAAIDSNFANFTYTPRSLPEDDTSMAILSMLQDMNFINNYKIDCPTLARFCLMVKKGYRDPPYHNWMHAFSVSHFCYLLYKNLELSNYLEDIEIFALFISCMCHDLDHRGTNNSFQVASKSVLAALYSSEGSVMERHHFAQAIAILNTHGCNIFDHFSRKDYQRMLDLMRDIILATDLAHHLRIFKDLQKMAEVGYDRNNRQHHRLLLCLLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEKAMGNRPMEMMDREKAYIPELQISFMEHIAMPIYKLLQDLFPKAAELYERVASNREHWTKVSHKFTIRGLPSNNSLDFLDEEYE 916
BLAST of Phosphodiesterase vs. Ensembl Mouse
Match: Pde2a (phosphodiesterase 2A, cGMP-stimulated [Source:MGI Symbol;Acc:MGI:2446107]) HSP 1 Score: 715.301 bits (1845), Expect = 0.000e+0 Identity = 371/729 (50.89%), Postives = 503/729 (69.00%), Query Frame = 1
Query: 586 KIISNQINQILELCGSLFDQDAGKLQKKVLSYLIQNTSAETGFLLLVCMDTVELLCQVIGQVIQEDPINFDAEENGIFDKVLKSKTGINLGCLTEAQLREISEIMNASKQETKIQNALCVPVRHQGTNDVIAIVCLINKSG----PAQFTNYDEQVINECFKYTTSVLFTTIAYQNERRLKLQTEKMLVVAKNIFSRMDNLNELLLMIMQEARNLTQAERCSVFLVDEDSNELVAKVFDGLPTSSDKNERLRLQDGTEIQQPVEIRFPKAQGIAGHVATTGEMLNIKKAYDHPLFYRGVDDETGFKTKNILCFPIQDDCGKTVGVAQLCNKIKGHFFTKMDEEIAKAFSIYCCISITHSLMYKKVEDAQHRSRLANELMMYHMQIPEDDIAWLSTFSIPPVSIFLSDFESFNSIPRNVKDRDTLMACISMFDGIGLISRWRINRRTLTKFIFMVKRNYRDPPYHNWMHAFSVAHFIFICIKNLPLDKQLTELELFALFVASLCHDIDHRGTNNSFQVQSNSILAALYSSEGSVLERHHFSQTVCILNTEGCNVFESLPQKEYXXXXXXXXXXXXXXXXXHHLQIFSKIEKMAQQGYDNLDSENHNLLLCLLMTSADLSDQTKNWRNTRSVAELIYKEFFRQGDLEKAIGNQPAEQMDRERAVVPNLQIAFLDGIVSPLYRVLSLLHPQTDCINHTIERTRENWSKISQKVASHEIKGNSEEIFRNKLVE 2760
K ++ +IL+LCG LFD DA LQ KVL YL Q T A LLLV D ++L C+VIG + + ++F G +V++ K I L LT ++++ ++ ++Q LCVPV + T+ V+A+ C NK G + FT+ DE VI CF YT +VL +T+A+Q E++LK + + +L VAKN+F+ +D+++ LL I+ EARNL+ AE CSVFL+D+ NELVAKVFDG G + EIR P QGIAGHVATTG++LNI AY HPLFYRGVDD TGF+T+NILCFPI+++ + +GVA+L NKI G +F+K DE++A AFSIYC ISI HSL+YKKV +AQ+RS LANE+MMYHM++ +D+ L I PV+ S+F +F PR++ + DT MA +SM + I+ ++I+ TL +F MVK+ YRDPPYHNWMHAFSV+HF ++ KNL L L ++E+FALF++ +CHD+DHRGTNNSFQV S S+LAALYSSEGSV+ERHHF+Q + ILNT GCN+F+ +K+Y R LDL+RDIILATDLAHHL+IF ++KMA+ GYD + ++H LLLCLLMTS DLSDQTK W+ TR +AELIYKEFF QGDLEKA+GN+P E MDRE+A +P LQI+F++ I P+Y++L L P+ + + RE+W+K+S K + N+ F ++ E
Sbjct: 215 KGYTDHDRKILQLCGELFDLDATSLQLKVLQYLQQETQATHCCLLLVSEDNLQLSCKVIGDKVLGEEVSFPLT-MGRLGQVVEDKQCIQLKDLTSDDVQQLQNMLGC-----ELQAMLCVPVISRATDQVVALACAFNKLGGDFPTSSFTDEDEHVIQHCFHYTGTVLTSTLAFQKEQKLKCECQALLQVAKNLFTHLDDVSVLLQEIITEARNLSNAEICSVFLLDQ--NELVAKVFDG---------------GVVDDESYEIRIPADQGIAGHVATTGQILNIPDAYAHPLFYRGVDDSTGFRTRNILCFPIKNENQEVIGVAELVNKINGPWFSKFDEDLATAFSIYCGISIAHSLLYKKVNEAQYRSHLANEMMMYHMKVSDDEYTKLLHDGIQPVAAIDSNFANFTYTPRSLPEDDTSMAILSMLQDMNFINNYKIDCPTLARFCLMVKKGYRDPPYHNWMHAFSVSHFCYLLYKNLELSNYLEDIEIFALFISCMCHDLDHRGTNNSFQVASKSVLAALYSSEGSVMERHHFAQAIAILNTHGCNIFDHFSRKDYQRMLDLMRDIILATDLAHHLRIFKDLQKMAEVGYDRNNRQHHRLLLCLLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEKAMGNRPMEMMDREKAYIPELQISFMEHIAMPIYKLLQDLFPKAAELYERVASNREHWTKVSHKFTIRGLPSNNSLDFLDEEYE 920
BLAST of Phosphodiesterase vs. UniProt/SwissProt
Match: sp|P14099|PDE2A_BOVIN (cGMP-dependent 3',5'-cyclic phosphodiesterase OS=Bos taurus OX=9913 GN=PDE2A PE=1 SV=2) HSP 1 Score: 733.406 bits (1892), Expect = 0.000e+0 Identity = 372/712 (52.25%), Postives = 501/712 (70.37%), Query Frame = 1
Query: 595 SNQINQILELCGSLFDQDAGKLQKKVLSYLIQNTSAETGFLLLVCMDTVELLCQVIGQVIQEDPINFDAEENGIFDKVLKSKTGINLGCLTEAQLREISEIMNASKQETKIQNALCVPVRHQGTNDVIAIVCLINKSGPAQFTNYDEQVINECFKYTTSVLFTTIAYQNERRLKLQTEKMLVVAKNIFSRMDNLNELLLMIMQEARNLTQAERCSVFLVDEDSNELVAKVFDGLPTSSDKNERLRLQDGTEIQQPVEIRFPKAQGIAGHVATTGEMLNIKKAYDHPLFYRGVDDETGFKTKNILCFPIQDDCGKTVGVAQLCNKIKGHFFTKMDEEIAKAFSIYCCISITHSLMYKKVEDAQHRSRLANELMMYHMQIPEDDIAWLSTFSIPPVSIFLSDFESFNSIPRNVKDRDTLMACISMFDGIGLISRWRINRRTLTKFIFMVKRNYRDPPYHNWMHAFSVAHFIFICIKNLPLDKQLTELELFALFVASLCHDIDHRGTNNSFQVQSNSILAALYSSEGSVLERHHFSQTVCILNTEGCNVFESLPQKEYXXXXXXXXXXXXXXXXXHHLQIFSKIEKMAQQGYDNLDSENHNLLLCLLMTSADLSDQTKNWRNTRSVAELIYKEFFRQGDLEKAIGNQPAEQMDRERAVVPNLQIAFLDGIVSPLYRVLSLLHPQTDCINHTIERTRENWSKISQKVASHEIKGNS 2730
+NQ +IL+LCG L+D DA LQ KVL YL Q T A LLLV D ++L C+VIG + E+ I+F G +V++ K I L LT ++++ ++ ++Q LCVPV + T+ V+A+ C NK G FT+ DE VI CF YT++VL +T+A+Q E++LK + + +L VAKN+F+ +D+++ LL I+ EARNL+ AE CSVFL+D+ NELVAKVFDG G + EIR P QGIAGHVATTG++LNI AY HPLFYRGVDD TGF+T+NILCFPI+++ + +GVA+L NKI G +F+K DE++A AFSIYC ISI HSL+YKKV +AQ+RS LANE+MMYHM++ +D+ L I PV+ S+F SF PR++ + DT MA +SM + I+ ++I+ TL +F MVK+ YRDPPYHNWMHAFSV+HF ++ KNL L L ++E+FALF++ +CHD+DHRGTNNSFQV S S+LAALYSSEGSV+ERHHF+Q + ILNT GCN+F+ +K+Y R LDL+RDIILATDLAHHL+IF ++KMA+ GYD + ++H+LLLCLLMTS DLSDQTK W+ TR +AELIYKEFF QGDLEKA+GN+P E MDRE+A +P LQI+F++ I P+Y++L L P+ + + RE+W+K+S K + N+
Sbjct: 203 TNQDRKILQLCGELYDLDASSLQLKVLQYLQQETQASRCCLLLVSEDNLQLSCKVIGDKVLEEEISFPLT-TGRLGQVVEDKKSIQLKDLTSEDMQQLQSMLGC-----EVQAMLCVPVISRATDQVVALACAFNKLGGDLFTDQDEHVIQHCFHYTSTVLTSTLAFQKEQKLKCECQALLQVAKNLFTHLDDVSVLLQEIITEARNLSNAEICSVFLLDQ--NELVAKVFDG---------------GVVEDESYEIRIPADQGIAGHVATTGQILNIPDAYAHPLFYRGVDDSTGFRTRNILCFPIKNENQEVIGVAELVNKINGPWFSKFDEDLATAFSIYCGISIAHSLLYKKVNEAQYRSHLANEMMMYHMKVSDDEYTKLLHDGIQPVAAIDSNFASFTYTPRSLPEDDTSMAILSMLQDMNFINNYKIDCPTLARFCLMVKKGYRDPPYHNWMHAFSVSHFCYLLYKNLELTNYLEDMEIFALFISCMCHDLDHRGTNNSFQVASKSVLAALYSSEGSVMERHHFAQAIAILNTHGCNIFDHFSRKDYQRMLDLMRDIILATDLAHHLRIFKDLQKMAEVGYDRTNKQHHSLLLCLLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEKAMGNRPMEMMDREKAYIPELQISFMEHIAMPIYKLLQDLFPKAAELYERVASNREHWTKVSHKFTIRGLPSNN 891
BLAST of Phosphodiesterase vs. UniProt/SwissProt
Match: sp|O00408|PDE2A_HUMAN (cGMP-dependent 3',5'-cyclic phosphodiesterase OS=Homo sapiens OX=9606 GN=PDE2A PE=1 SV=1) HSP 1 Score: 720.309 bits (1858), Expect = 0.000e+0 Identity = 369/722 (51.11%), Postives = 502/722 (69.53%), Query Frame = 1
Query: 595 SNQINQILELCGSLFDQDAGKLQKKVLSYLIQNTSAETGFLLLVCMDTVELLCQVIGQVIQEDPINFDAEENGIFDKVLKSKTGINLGCLTEAQLREISEIMNASKQETKIQNALCVPVRHQGTNDVIAIVCLINKSGPAQFTNYDEQVINECFKYTTSVLFTTIAYQNERRLKLQTEKMLVVAKNIFSRMDNLNELLLMIMQEARNLTQAERCSVFLVDEDSNELVAKVFDGLPTSSDKNERLRLQDGTEIQQPVEIRFPKAQGIAGHVATTGEMLNIKKAYDHPLFYRGVDDETGFKTKNILCFPIQDDCGKTVGVAQLCNKIKGHFFTKMDEEIAKAFSIYCCISITHSLMYKKVEDAQHRSRLANELMMYHMQIPEDDIAWLSTFSIPPVSIFLSDFESFNSIPRNVKDRDTLMACISMFDGIGLISRWRINRRTLTKFIFMVKRNYRDPPYHNWMHAFSVAHFIFICIKNLPLDKQLTELELFALFVASLCHDIDHRGTNNSFQVQSNSILAALYSSEGSVLERHHFSQTVCILNTEGCNVFESLPQKEYXXXXXXXXXXXXXXXXXHHLQIFSKIEKMAQQGYDNLDSENHNLLLCLLMTSADLSDQTKNWRNTRSVAELIYKEFFRQGDLEKAIGNQPAEQMDRERAVVPNLQIAFLDGIVSPLYRVLSLLHPQTDCINHTIERTRENWSKISQKVASHEIKGNSEEIFRNKLVE 2760
+++ +IL+LCG L+D DA LQ KVL YL Q T A LLLV D ++L C+VIG + + ++F G +V++ K I L LT ++++ ++ ++Q LCVPV + T+ V+A+ C NK FT+ DE VI CF YT++VL +T+A+Q E++LK + + +L VAKN+F+ +D+++ LL I+ EARNL+ AE CSVFL+D+ NELVAKVFDG G + EIR P QGIAGHVATTG++LNI AY HPLFYRGVDD TGF+T+NILCFPI+++ + +GVA+L NKI G +F+K DE++A AFSIYC ISI HSL+YKKV +AQ+RS LANE+MMYHM++ +D+ L I PV+ S+F SF PR++ + DT MA +SM + I+ ++I+ TL +F MVK+ YRDPPYHNWMHAFSV+HF ++ KNL L L ++E+FALF++ +CHD+DHRGTNNSFQV S S+LAALYSSEGSV+ERHHF+Q + ILNT GCN+F+ +K+Y R LDL+RDIILATDLAHHL+IF ++KMA+ GYD + ++H LLLCLLMTS DLSDQTK W+ TR +AELIYKEFF QGDLEKA+GN+P E MDRE+A +P LQI+F++ I P+Y++L L P+ + + RE+W+K+S K + N+ F ++ E
Sbjct: 224 TDRDRKILQLCGELYDLDASSLQLKVLQYLQQETRASRCCLLLVSEDNLQLSCKVIGDKVLGEEVSFPL--TGCLGQVVEDKKSIQLKDLTSEDVQQLQSMLGC-----ELQAMLCVPVISRATDQVVALACAFNKLEGDLFTDEDEHVIQHCFHYTSTVLTSTLAFQKEQKLKCECQALLQVAKNLFTHLDDVSVLLQEIITEARNLSNAEICSVFLLDQ--NELVAKVFDG---------------GVVDDESYEIRIPADQGIAGHVATTGQILNIPDAYAHPLFYRGVDDSTGFRTRNILCFPIKNENQEVIGVAELVNKINGPWFSKFDEDLATAFSIYCGISIAHSLLYKKVNEAQYRSHLANEMMMYHMKVSDDEYTKLLHDGIQPVAAIDSNFASFTYTPRSLPEDDTSMAILSMLQDMNFINNYKIDCPTLARFCLMVKKGYRDPPYHNWMHAFSVSHFCYLLYKNLELTNYLEDIEIFALFISCMCHDLDHRGTNNSFQVASKSVLAALYSSEGSVMERHHFAQAIAILNTHGCNIFDHFSRKDYQRMLDLMRDIILATDLAHHLRIFKDLQKMAEVGYDRNNKQHHRLLLCLLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEKAMGNRPMEMMDREKAYIPELQISFMEHIAMPIYKLLQDLFPKAAELYERVASNREHWTKVSHKFTIRGLPSNNSLDFLDEEYE 921
BLAST of Phosphodiesterase vs. UniProt/SwissProt
Match: sp|Q01062|PDE2A_RAT (cGMP-dependent 3',5'-cyclic phosphodiesterase OS=Rattus norvegicus OX=10116 GN=Pde2a PE=1 SV=2) HSP 1 Score: 716.072 bits (1847), Expect = 0.000e+0 Identity = 365/707 (51.63%), Postives = 496/707 (70.16%), Query Frame = 1
Query: 610 QILELCGSLFDQDAGKLQKKVLSYLIQNTSAETGFLLLVCMDTVELLCQVIGQVIQEDPINFDAEENGIFDKVLKSKTGINLGCLTEAQLREISEIMNASKQETKIQNALCVPVRHQGTNDVIAIVCLINKSGPAQFTNYDEQVINECFKYTTSVLFTTIAYQNERRLKLQTEKMLVVAKNIFSRMDNLNELLLMIMQEARNLTQAERCSVFLVDEDSNELVAKVFDGLPTSSDKNERLRLQDGTEIQQPVEIRFPKAQGIAGHVATTGEMLNIKKAYDHPLFYRGVDDETGFKTKNILCFPIQDDCGKTVGVAQLCNKIKGHFFTKMDEEIAKAFSIYCCISITHSLMYKKVEDAQHRSRLANELMMYHMQIPEDDIAWLSTFSIPPVSIFLSDFESFNSIPRNVKDRDTLMACISMFDGIGLISRWRINRRTLTKFIFMVKRNYRDPPYHNWMHAFSVAHFIFICIKNLPLDKQLTELELFALFVASLCHDIDHRGTNNSFQVQSNSILAALYSSEGSVLERHHFSQTVCILNTEGCNVFESLPQKEYXXXXXXXXXXXXXXXXXHHLQIFSKIEKMAQQGYDNLDSENHNLLLCLLMTSADLSDQTKNWRNTRSVAELIYKEFFRQGDLEKAIGNQPAEQMDRERAVVPNLQIAFLDGIVSPLYRVLSLLHPQTDCINHTIERTRENWSKISQKVASHEIKGNS 2730
+IL+LCG L+D DA LQ KVL YL Q T A LLLV D ++L C+VIG+ + + ++F G +V++ K I L LT ++++ ++ +++ LCVPV + T+ V+A+ C NK G FT+ DE+ I CF YT +VL +T+A+Q E++LK + + +L VAKN+F+ +D+++ LL I+ EARNL+ AE CSVFL+D+ NELVAKVFDG G + EIR P QGIAGHVATTG++LNI AY HPLFYRGVDD TGF+T+NILCFPI+++ + +GVA+L NKI G +F+K DE++A AFSIYC ISI HSL+YKKV +AQ+RS LANE+MMYHM++ +D+ L I PV+ S+F +F PR++ + DT MA +SM + I+ ++I+ TL +F MVK+ YRDPPYHNWMHAFSV+HF ++ KNL L L ++E+FALF++ +CHD+DHRGTNNSFQV S S+LAALYSSEGSV+ERHHF+Q + ILNT GCN+F+ +K+Y R LDL+RDIILATDLAHHL+IF ++KMA+ GYD + ++H LLLCLLMTS DLSDQTK W+ TR +AELIYKEFF QGDLEKA+GN+P E MDRE+A +P LQI+F++ I P+Y++L L P+ + + RE+W+K+S K + N+
Sbjct: 216 KILQLCGELYDLDATSLQLKVLRYLQQETQATHCCLLLVSEDNLQLSCKVIGEKVLGEEVSFPLT-MGRLGQVVEDKQCIQLKDLTSDDVQQLQNMLGC-----ELRAMLCVPVISRATDQVVALACAFNKLGGDFFTDEDERAIQHCFHYTGTVLTSTLAFQKEQKLKCECQALLQVAKNLFTHLDDVSVLLQEIITEARNLSNAEICSVFLLDQ--NELVAKVFDG---------------GVVDDESYEIRIPADQGIAGHVATTGQILNIPDAYAHPLFYRGVDDSTGFRTRNILCFPIKNENQEVIGVAELVNKINGPWFSKFDEDLATAFSIYCGISIAHSLLYKKVNEAQYRSHLANEMMMYHMKVSDDEYTKLLHDGIQPVAAIDSNFANFTYTPRSLPEDDTSMAILSMLQDMNFINNYKIDCPTLARFCLMVKKGYRDPPYHNWMHAFSVSHFCYLLYKNLELSNYLEDIEIFALFISCMCHDLDHRGTNNSFQVASKSVLAALYSSEGSVMERHHFAQAIAILNTHGCNIFDHFSRKDYQRMLDLMRDIILATDLAHHLRIFKDLQKMAEVGYDRNNKQHHRLLLCLLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEKAMGNRPMEMMDREKAYIPELQISFMEHIAMPIYKLLQDLFPKAAELYERVASNREHWTKVSHKFTIRGLPSNN 899
BLAST of Phosphodiesterase vs. UniProt/SwissProt
Match: sp|Q922S4|PDE2A_MOUSE (cGMP-dependent 3',5'-cyclic phosphodiesterase OS=Mus musculus OX=10090 GN=Pde2a PE=1 SV=4) HSP 1 Score: 715.301 bits (1845), Expect = 0.000e+0 Identity = 371/729 (50.89%), Postives = 503/729 (69.00%), Query Frame = 1
Query: 586 KIISNQINQILELCGSLFDQDAGKLQKKVLSYLIQNTSAETGFLLLVCMDTVELLCQVIGQVIQEDPINFDAEENGIFDKVLKSKTGINLGCLTEAQLREISEIMNASKQETKIQNALCVPVRHQGTNDVIAIVCLINKSG----PAQFTNYDEQVINECFKYTTSVLFTTIAYQNERRLKLQTEKMLVVAKNIFSRMDNLNELLLMIMQEARNLTQAERCSVFLVDEDSNELVAKVFDGLPTSSDKNERLRLQDGTEIQQPVEIRFPKAQGIAGHVATTGEMLNIKKAYDHPLFYRGVDDETGFKTKNILCFPIQDDCGKTVGVAQLCNKIKGHFFTKMDEEIAKAFSIYCCISITHSLMYKKVEDAQHRSRLANELMMYHMQIPEDDIAWLSTFSIPPVSIFLSDFESFNSIPRNVKDRDTLMACISMFDGIGLISRWRINRRTLTKFIFMVKRNYRDPPYHNWMHAFSVAHFIFICIKNLPLDKQLTELELFALFVASLCHDIDHRGTNNSFQVQSNSILAALYSSEGSVLERHHFSQTVCILNTEGCNVFESLPQKEYXXXXXXXXXXXXXXXXXHHLQIFSKIEKMAQQGYDNLDSENHNLLLCLLMTSADLSDQTKNWRNTRSVAELIYKEFFRQGDLEKAIGNQPAEQMDRERAVVPNLQIAFLDGIVSPLYRVLSLLHPQTDCINHTIERTRENWSKISQKVASHEIKGNSEEIFRNKLVE 2760
K ++ +IL+LCG LFD DA LQ KVL YL Q T A LLLV D ++L C+VIG + + ++F G +V++ K I L LT ++++ ++ ++Q LCVPV + T+ V+A+ C NK G + FT+ DE VI CF YT +VL +T+A+Q E++LK + + +L VAKN+F+ +D+++ LL I+ EARNL+ AE CSVFL+D+ NELVAKVFDG G + EIR P QGIAGHVATTG++LNI AY HPLFYRGVDD TGF+T+NILCFPI+++ + +GVA+L NKI G +F+K DE++A AFSIYC ISI HSL+YKKV +AQ+RS LANE+MMYHM++ +D+ L I PV+ S+F +F PR++ + DT MA +SM + I+ ++I+ TL +F MVK+ YRDPPYHNWMHAFSV+HF ++ KNL L L ++E+FALF++ +CHD+DHRGTNNSFQV S S+LAALYSSEGSV+ERHHF+Q + ILNT GCN+F+ +K+Y R LDL+RDIILATDLAHHL+IF ++KMA+ GYD + ++H LLLCLLMTS DLSDQTK W+ TR +AELIYKEFF QGDLEKA+GN+P E MDRE+A +P LQI+F++ I P+Y++L L P+ + + RE+W+K+S K + N+ F ++ E
Sbjct: 215 KGYTDHDRKILQLCGELFDLDATSLQLKVLQYLQQETQATHCCLLLVSEDNLQLSCKVIGDKVLGEEVSFPLT-MGRLGQVVEDKQCIQLKDLTSDDVQQLQNMLGC-----ELQAMLCVPVISRATDQVVALACAFNKLGGDFPTSSFTDEDEHVIQHCFHYTGTVLTSTLAFQKEQKLKCECQALLQVAKNLFTHLDDVSVLLQEIITEARNLSNAEICSVFLLDQ--NELVAKVFDG---------------GVVDDESYEIRIPADQGIAGHVATTGQILNIPDAYAHPLFYRGVDDSTGFRTRNILCFPIKNENQEVIGVAELVNKINGPWFSKFDEDLATAFSIYCGISIAHSLLYKKVNEAQYRSHLANEMMMYHMKVSDDEYTKLLHDGIQPVAAIDSNFANFTYTPRSLPEDDTSMAILSMLQDMNFINNYKIDCPTLARFCLMVKKGYRDPPYHNWMHAFSVSHFCYLLYKNLELSNYLEDIEIFALFISCMCHDLDHRGTNNSFQVASKSVLAALYSSEGSVMERHHFAQAIAILNTHGCNIFDHFSRKDYQRMLDLMRDIILATDLAHHLRIFKDLQKMAEVGYDRNNRQHHRLLLCLLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEKAMGNRPMEMMDREKAYIPELQISFMEHIAMPIYKLLQDLFPKAAELYERVASNREHWTKVSHKFTIRGLPSNNSLDFLDEEYE 920
BLAST of Phosphodiesterase vs. UniProt/SwissProt
Match: sp|P30645|PDE2_CAEEL (Probable 3',5'-cyclic phosphodiesterase pde-2 OS=Caenorhabditis elegans OX=6239 GN=pde-2 PE=3 SV=4) HSP 1 Score: 325.479 bits (833), Expect = 1.165e-95 Identity = 193/535 (36.07%), Postives = 311/535 (58.13%), Query Frame = 1
Query: 1168 DNLNELLLMIMQEARNLTQAERCSVFLVDEDSNELVAKVFDGLPTSSDKNERLRLQDGTEIQQPVEIRFPKAQGIAGHVATTGEMLNIKKAYDHPLFYRGVDDETGFKTKNILCFPIQDDCGKTVGVAQLCNKIKGHFFTKMDEEIAKAFSIYCCISITHSLMYKKVEDAQHRSRLANELMMYHMQ--IPEDDIAWLSTFSIPPVSIFLSDFESFNSIPRNVKDRDTLMACISMFDGIGLISRWRINRRTLTKFIFMVKRNYRDPPYHNWMHAFSVAHFIFICIKNLPLDKQLTELELFALFVASLCHDIDHRGTNNSFQVQS--NSILAALYSSEGSVLERHHFSQTVCILNTEGCNVFESLPQKEYXXXXXXXXXXXXXXXXXHHLQIFSKIEKMAQQGYDNLDSENHNLLLCLLMTSADLSDQTKNWRNTRSVAELIYKEFFRQGDLEKAIGNQPAEQMDRERAVVPNLQIAFLDGIVSPLYRVLSLLHPQTDCINHTIERTRENWSKISQKVASHEIKGNSEEIFRNKLVE 2760
+NL+ L+ I+ EA+ T+AE +VFL DED+ ++V +F+ NE + L G +F GI G VA+T +NI+ P F +D++ K +N++ FP+ D +GV L NK G F++ DE+ K FS + SI H+++ K++E+ + R + E + I E DI L + F +F F+ PR+V + A + F+ +G +++N+R L+ + V YR PYHNW HAF+V HF ++ ++ + + L+++E +L +A LCHDIDHRGT NSFQ+QS + L+ LYS+EGSVLERHHF+QT+ +L E C++ E+LP ++ ++ IR++ILATD++ HL+ +I+ M +GY+ + ++ LL+CL+MT++DLSDQ KN+ N + +AE IY EFF QGDLE +G +P E MDR A VP +QI FL I P++++L+ + P+ + I+ W + ++V ++ N+ E R++ +E
Sbjct: 176 NNLSALISCIIAEAKKNTEAEDYAVFLHDEDNKQMV--LFN--------NETM-LMTGK--------KFDMGYGIVGKVASTMRTMNIRDVSRCPFFNEEIDEQFSIKARNLIAFPLIDSSCSLIGVIVLYNKENG--FSRHDEKYIKRFSYFVANSIAHAILAKQIEEVRTRIHMVEEFKIQGEDAVIEEVDIMRLVNDPLRDWRYFSQNFADFSFPPRSVGENHFHRASMMFFEDLGFSMLYKLNKRKLSYLVLRVSAGYRPVPYHNWSHAFAVTHFCWLTLRTDAIRRALSDMERLSLLIACLCHDIDHRGTTNSFQMQSLQKTPLSVLYSTEGSVLERHHFAQTIKLLQQEECSILENLPAADFRTIVNTIREVILATDISAHLRKQERIKTMISEGYNPMSFDHRYLLMCLVMTASDLSDQAKNFHNAKRIAENIYLEFFAQGDLELQLGVKPLEMMDRTNAYVPTVQIDFLFKIGVPVFQLLASVVPEGRTTSEAIDANHLCWVALDEEVRNNPSATNTLEYLRDENLE 689
BLAST of Phosphodiesterase vs. TrEMBL
Match: A0A3Q0KMK5 (Phosphodiesterase OS=Schistosoma mansoni OX=6183 PE=3 SV=1) HSP 1 Score: 853.973 bits (2205), Expect = 0.000e+0 Identity = 457/919 (49.73%), Postives = 624/919 (67.90%), Query Frame = 1
Query: 169 EVSSLLGVVISYDEFLSKSKYAAKILFPLATAVQM-----HQVS----------EIKHPKIRAMCTIRRTSFLYVSDLEDLSEIISSGELDILKSNSYDILVIVSVSSSQPKESLILTFFQKFNENSENRSKRLDFLEKQMSLTLSRLMRI----------------HP--------NKIISNQINQ-ILELCGSLFDQDAGKLQKKVLSYLIQNTSAETGFLLLVCMDTVELLCQVIGQVIQEDPINFDAEENGIFDKVLKS-KT--GINLGCLTEAQLREISEIMNA----------SKQETKIQNALCVPVRHQGTNDVIAIVCLINKSGPAQFTNYDEQVINECFKYTTSVLFTTIAYQNERRLKLQTEKMLVVAKNIFSRMDNLNELLLMIMQEARNLTQAERCSVFLVDEDSNELVAKVFDGLPTSSDKNERLRLQDGTEIQQPVEIRFPKAQGIAGHVATTGEMLNIKKAYDHPLFYRGVDDETGFKTKNILCFPIQDDCGKTVGVAQLCNKIKGHFFTKMDEEIAKAFSIYCCISITHSLMYKKVEDAQHRSRLANELMMYHMQIPEDDIAWLSTFSIPPVSIFLSDFESFNSIPRNVK-DRDTLMACISMFDGIGLISRWRINRRTLTKFIFMVKRNYRDPPYHNWMHAFSVAHFIFICIKNLPL-DKQLTELELFALFVASLCHDIDHRGTNNSFQVQSNSILAALYSSEGSVLERHHFSQTVCILNTEGCNVFESLPQKEYXXXXXXXXXXXXXXXXXHHLQIFSKIEKMAQQGYDNLDSENHNLLLCLLMTSADLSDQTKNWRNTRSVAELIYKEFFRQGDLEKAIGNQPAEQMDRERAVVPNLQIAFLDGIVSPLYRVLSLLHPQTDCINHTIERTRENWSKISQKVASHEIKGNSEEIFRNKLVE 2760
+VS LLG +IS E L +S+ AAKILFP ++ HQ S EI++ + + ++ + +++ L +S+ + D+ +N + ++ ++ + F + + L+ Q+S TL+R++R+ +P + IS + N IL+LC SL+D +A +LQ KVL Y+++ T++E GF+++ +DT EL+C G I E+ E + F+++++S KT +L E L I + NA + +I + LC PV + + IA+VCLINK +QFT DE++I ECF++ +L +++AYQNER ++ +TE ML VA+NIF+ M +L LLL IMQEA+NLT+AERCSVFL+D ++N LVAKV DGLPT+ +KN R DG + P EIR QGIAG+VATTGE+LNIK AY HPLFYRGVD ETGF+T+NILCFPI+++ VGVAQLCNKI FFT+ DE++AK FSIYCCISI HSLMYK V+DAQHR++LANELMMYHM++ ED WL+T I ++ FL + SF S+PRN++ + +T + +SMF + LI+RWRI+RRTL +FI MV+R YR+P YHNWMHAFSVAHF+++CIKNLPL + QL ++E+ ALFVASLCHDIDHRGTNNSFQVQS S+LAALYSSEGSVLERHHFSQT+C+LNTEGCN+FE++ +++Y + LD IRDII+ATDL+HHL+I K+E+++ +GYD SE+H LLLCLLMTSADLSDQTK+W NT VA+LIY+EFF+QGD+EK++G+ P + MDRERA VPNLQI+FLD I++PLY+VL+ L+PQ I TIE+ R+NW I + V IKGN EIF + LVE
Sbjct: 16 DVSVLLGSIISRREMLEQSQNAAKILFPTCWLAELVISNRHQPSVNCPLEVLIREIRNSTDQEI-NVKEVTTNFITQLTSVSKSQNQPNFDLTNNNQH--MISFELNKDNEYGEYVAHFVMILESLPKAHLHKAQLLKNQLSSTLNRIIRLEQFNEFSSTSTLLKQRYPCCSQGTEASTWISREDNMLILKLCESLWDTEANRLQHKVLRYVMERTNSENGFIVMRNIDTSELVCHCTGNEIFEESTYI--ENDSFFNEIMQSGKTFKATHLNSEQEHTLLSILSVHNAYMNNENYVTNQNADIQIHSVLCSPVFTRSCDSPIAVVCLINKRD-SQFTQSDERIIEECFRFVAPILLSSLAYQNERYIRGRTEDMLKVARNIFTHMMDLTNLLLKIMQEAQNLTKAERCSVFLLDSETNVLVAKVLDGLPTAPNKNTRFTTADGKIVTLPEEIRLSLNQGIAGYVATTGELLNIKDAYAHPLFYRGVDKETGFRTRNILCFPIKNEKDGIVGVAQLCNKINHPFFTRADEDVAKTFSIYCCISIVHSLMYKNVQDAQHRTKLANELMMYHMKVDEDKKNWLTTCEIKDINTFLPNASSFESLPRNIQPENETYLCTLSMFHSLNLINRWRISRRTLAQFILMVRRGYRNPAYHNWMHAFSVAHFVYVCIKNLPLANNQLDDIEILALFVASLCHDIDHRGTNNSFQVQSKSVLAALYSSEGSVLERHHFSQTICVLNTEGCNIFENVSKEDYGQLLDHIRDIIVATDLSHHLRIMPKLEELSHRGYDGTKSEDHYLLLCLLMTSADLSDQTKSWNNTVYVAKLIYEEFFQQGDMEKSLGHNPIDSMDRERACVPNLQISFLDYIITPLYKVLNNLYPQCSSILDTIEKNRDNWKIILELVEKGYIKGNGSEIFNHNLVE 928
BLAST of Phosphodiesterase vs. TrEMBL
Match: A0A4Z2CV85 (Phosphodiesterase OS=Schistosoma japonicum OX=6182 GN=EWB00_007250 PE=3 SV=1) HSP 1 Score: 850.892 bits (2197), Expect = 0.000e+0 Identity = 461/917 (50.27%), Postives = 621/917 (67.72%), Query Frame = 1
Query: 169 EVSSLLGVVISYDEFLSKSKYAAKILFPLATAVQM-----HQVS-----EIKHPKIRAM---CTIRRTSFLYVSDLEDLSEIISSGELDILKSNSYDILVIVSVSSSQPKESLILTFFQKFNENSENRSKRLDFLEKQMSLTLSRLMR------------------------IHPNKIISNQINQ-ILELCGSLFDQDAGKLQKKVLSYLIQNTSAETGFLLLVCMDTVELLCQVIGQVIQEDPINFDAEENGIFDKVLKS-KTGINLGCLTEAQ--LREISEIMNAS----------KQETKIQNALCVPVRHQGTNDVIAIVCLINKSGPAQFTNYDEQVINECFKYTTSVLFTTIAYQNERRLKLQTEKMLVVAKNIFSRMDNLNELLLMIMQEARNLTQAERCSVFLVDEDSNELVAKVFDGLPTSSDKNERLRLQDGTEIQQPVEIRFPKAQGIAGHVATTGEMLNIKKAYDHPLFYRGVDDETGFKTKNILCFPIQDDCGKTVGVAQLCNKIKGHFFTKMDEEIAKAFSIYCCISITHSLMYKKVEDAQHRSRLANELMMYHMQIPEDDIAWLSTFSIPPVSIFLSDFESFNSIPRNVK-DRDTLMACISMFDGIGLISRWRINRRTLTKFIFMVKRNYRDPPYHNWMHAFSVAHFIFICIKNLPL-DKQLTELELFALFVASLCHDIDHRGTNNSFQVQSNSILAALYSSEGSVLERHHFSQTVCILNTEGCNVFESLPQKEYXXXXXXXXXXXXXXXXXHHLQIFSKIEKMAQQGYDNLDSENHNLLLCLLMTSADLSDQTKNWRNTRSVAELIYKEFFRQGDLEKAIGNQPAEQMDRERAVVPNLQIAFLDGIVSPLYRVLSLLHPQTDCINHTIERTRENWSKISQKVASHEIKGNSEEIFRNKLVE 2760
+VS LLG +IS E L +S+ AAKILFP ++ HQ S E+ +I + T++ + ++ L +S+ + + +N Y ++ +++ + + F + + + Q+S TL+R++R I + I+ + N+ IL+LC SL+D +LQ KVL YL+Q T++E GF+++ DT EL+C IG I ++ E + +F+++++S KT + +E + L + I NA +E +I + LC PV + + I +VCLINK +QFT DE +I ECF+YT +L ++++ QNER ++ +TE ML VA+NIF+ M +L LLL IMQEA+NLT+AERCSVFL+D ++N LVAKV DGLPT+ +KN DG + P EIR QGIAGHVATTGE+LNIK AY HPLFYRGVD ETGF+T+NILCFPI+++ VGVAQLCNKI FFT+ DE++AK FSIYCCISI HSLMYK V+DAQHR++LANELMMYHM++ ED WLST I ++ FL + SF S+PRN++ + +T + +SMF + LI+RWRI+RRTL +FI MV+R YR+P YHNWMHAF+VAHFI++CIKNLPL +KQL ++E+ ALFVASLCHDIDHRGTNNSFQVQS S+LAALYSSEGSVLERHHFSQT+C+LNT+GCN+FE++ +++Y + LD IRDIILATDL+HHL+I SK+E+M+ +GYD SE+H LLLCLLMTSADLSDQTK W NT VA+LIY+EFF+QGD+EK++G+ P + MDRERA VPNLQI+FLD I+ PLYRVL+ L+PQ I TIE+ R+NW I + V EIKGN EIF + L+E
Sbjct: 17 DVSILLGSIISRREMLEQSQNAAKILFPSCWIAELVISNRHQPSINCPLEVLMREISSSNQEITVKEVTTSFIVHLASVSKNQNMSNFNTKNTNQY--MISFELNNEDKRSDYVAHFVMILESLPKAHLHKAQLFKSQLSCTLNRIIRLEQFNELSSTLSSLKQRYPCCSQGIEASTWINRKDNELILKLCESLWDTQTNRLQHKVLRYLMQRTNSENGFIVMRNTDTSELVCYCIGDEIFDESTYI--ENDSLFNEIMQSGKTFTSTTPNSEQKQVLLSVLSIHNAYMNNEHPITNLHEEMEINSFLCSPVFTRSSEYPIGVVCLINKKD-SQFTQSDEFIIEECFRYTAPILLSSLSCQNERYIRDRTEDMLKVARNIFTHMMDLTNLLLKIMQEAQNLTKAERCSVFLLDSETNVLVAKVLDGLPTAPNKNTHFTTTDGKIVTLPEEIRLSLNQGIAGHVATTGELLNIKDAYAHPLFYRGVDKETGFRTRNILCFPIKNEKDGIVGVAQLCNKINHPFFTRADEDVAKTFSIYCCISIVHSLMYKNVQDAQHRTKLANELMMYHMKVDEDKKNWLSTCEIKDINSFLPNTSSFESLPRNIQPENETYLCTLSMFHNLNLINRWRISRRTLAQFILMVRRGYRNPAYHNWMHAFTVAHFIYVCIKNLPLANKQLEDIEILALFVASLCHDIDHRGTNNSFQVQSKSVLAALYSSEGSVLERHHFSQTICVLNTDGCNIFENVSKEDYSQLLDHIRDIILATDLSHHLRIMSKLEEMSHRGYDVTKSEDHYLLLCLLMTSADLSDQTKPWNNTVYVAKLIYEEFFQQGDMEKSLGHNPIDSMDRERACVPNLQISFLDYIILPLYRVLNNLYPQCSSILDTIEKNRDNWKTILELVEKGEIKGNGSEIFNHNLIE 928
BLAST of Phosphodiesterase vs. TrEMBL
Match: A0A5K4ENT0 (Phosphodiesterase OS=Schistosoma mansoni OX=6183 PE=4 SV=1) HSP 1 Score: 837.025 bits (2161), Expect = 0.000e+0 Identity = 419/731 (57.32%), Postives = 548/731 (74.97%), Query Frame = 1
Query: 613 ILELCGSLFDQDAGKLQKKVLSYLIQNTSAETGFLLLVCMDTVELLCQVIGQVIQEDPINFDAEENGIFDKVLKS-KT--GINLGCLTEAQLREISEIMNA----------SKQETKIQNALCVPVRHQGTNDVIAIVCLINKSGPAQFTNYDEQVINECFKYTTSVLFTTIAYQNERRLKLQTEKMLVVAKNIFSRMDNLNELLLMIMQEARNLTQAERCSVFLVDEDSNELVAKVFDGLPTSSDKNERLRLQDGTEIQQPVEIRFPKAQGIAGHVATTGEMLNIKKAYDHPLFYRGVDDETGFKTKNILCFPIQDDCGKTVGVAQLCNKIKGHFFTKMDEEIAKAFSIYCCISITHSLMYKKVEDAQHRSRLANELMMYHMQIPEDDIAWLSTFSIPPVSIFLSDFESFNSIPRNVK-DRDTLMACISMFDGIGLISRWRINRRTLTKFIFMVKRNYRDPPYHNWMHAFSVAHFIFICIKNLPL-DKQLTELELFALFVASLCHDIDHRGTNNSFQVQSNSILAALYSSEGSVLERHHFSQTVCILNTEGCNVFESLPQKEYXXXXXXXXXXXXXXXXXHHLQIFSKIEKMAQQGYDNLDSENHNLLLCLLMTSADLSDQTKNWRNTRSVAELIYKEFFRQGDLEKAIGNQPAEQMDRERAVVPNLQIAFLDGIVSPLYRVLSLLHPQTDCINHTIERTRENWSKISQKVASHEIKGNSEEIFRNKLVE 2760
IL+LC SL+D +A +LQ KVL Y+++ T++E GF+++ +DT EL+C G I E+ E + F+++++S KT +L E L I + NA + +I + LC PV + + IA+VCLINK +QFT DE++I ECF++ +L +++AYQNER ++ +TE ML VA+NIF+ M +L LLL IMQEA+NLT+AERCSVFL+D ++N LVAKV DGLPT+ +KN R DG + P EIR QGIAG+VATTGE+LNIK AY HPLFYRGVD ETGF+T+NILCFPI+++ VGVAQLCNKI FFT+ DE++AK FSIYCCISI HSLMYK V+DAQHR++LANELMMYHM++ ED WL+T I ++ FL + SF S+PRN++ + +T + +SMF + LI+RWRI+RRTL +FI MV+R YR+P YHNWMHAFSVAHF+++CIKNLPL + QL ++E+ ALFVASLCHDIDHRGTNNSFQVQS S+LAALYSSEGSVLERHHFSQT+C+LNTEGCN+FE++ +++Y + LD IRDII+ATDL+HHL+I K+E+++ +GYD SE+H LLLCLLMTSADLSDQTK+W NT VA+LIY+EFF+QGD+EK++G+ P + MDRERA VPNLQI+FLD I++PLY+VL+ L+PQ I TIE+ R+NW I + V IKGN EIF + LVE
Sbjct: 69 ILKLCESLWDTEANRLQHKVLRYVMERTNSENGFIVMRNIDTSELVCHCTGNEIFEESTYI--ENDSFFNEIMQSGKTFKATHLNSEQEHTLLSILSVHNAYMNNENYVTNQNADIQIHSVLCSPVFTRSCDSPIAVVCLINKRD-SQFTQSDERIIEECFRFVAPILLSSLAYQNERYIRGRTEDMLKVARNIFTHMMDLTNLLLKIMQEAQNLTKAERCSVFLLDSETNVLVAKVLDGLPTAPNKNTRFTTADGKIVTLPEEIRLSLNQGIAGYVATTGELLNIKDAYAHPLFYRGVDKETGFRTRNILCFPIKNEKDGIVGVAQLCNKINHPFFTRADEDVAKTFSIYCCISIVHSLMYKNVQDAQHRTKLANELMMYHMKVDEDKKNWLTTCEIKDINTFLPNASSFESLPRNIQPENETYLCTLSMFHSLNLINRWRISRRTLAQFILMVRRGYRNPAYHNWMHAFSVAHFVYVCIKNLPLANNQLDDIEILALFVASLCHDIDHRGTNNSFQVQSKSVLAALYSSEGSVLERHHFSQTICVLNTEGCNIFENVSKEDYGQLLDHIRDIIVATDLSHHLRIMPKLEELSHRGYDGTKSEDHYLLLCLLMTSADLSDQTKSWNNTVYVAKLIYEEFFQQGDMEKSLGHNPIDSMDRERACVPNLQISFLDYIITPLYKVLNNLYPQCSSILDTIEKNRDNWKIILELVEKGYIKGNGSEIFNHNLVE 796
BLAST of Phosphodiesterase vs. TrEMBL
Match: A0A094ZED4 (Phosphodiesterase OS=Schistosoma haematobium OX=6185 GN=MS3_00246 PE=3 SV=1) HSP 1 Score: 833.558 bits (2152), Expect = 0.000e+0 Identity = 457/919 (49.73%), Postives = 625/919 (68.01%), Query Frame = 1
Query: 169 EVSSLLGVVISYDEFLSKSKYAAKILFPLATAVQM-----HQVS----------EIKHPKIRAMCTIRRTSFLYVSDLEDLSEIISSGELDILKSNSYDILVIVSVSSSQPKESLILTFFQKFNENSE-NRSKRLDFLEKQMSLTLSRLMRIHP--------NKIISNQINQ-ILELCGSLFDQDAGKLQKKVLSYLIQNTSAETGFLLLVCMDTVELLCQVIGQVIQEDPINFDAEENGIFDKVLKSKTGINLGCLTEAQ---LREISEIMNA--------SKQETKIQ--NALCVPVRHQGTNDVIAIVCLINKSGPAQFTNYDEQVINECFKYTTSVLFTTIAYQNERRLKLQTEKMLVVAKNIFSRMDNLNELLLMIMQEARNLTQAERCSVFLVDEDSNELVAKVFDGLPTSSDKNERLRLQDGTEI---------------QQPVEIRFPKAQGIAGHVATTGEMLNIKKAYDHPLFYRGVDDETGFKTKNILCFPIQDDCGKTVGVAQLCNKIKGHFFTKMDEEIAKAFSIYCCISITHSLMYKKVEDAQHRSRLANELMMYHMQIPEDDIAWLSTFSIPPVSIFLSDFESFNSIPRNVK-DRDTLMACISMFDGIGLISRWRINRRTLTKFIFMVKRNYRDPPYHNWMHAFSVAHFIFICIKNLPL-DKQLTELELFALFVASLCHDIDHRGTNNSFQVQSNSILAALYSSEGSVLERHHFSQTVCILNTEGCNVFESLPQKEYXXXXXXXXXXXXXXXXXHHLQIFSKIEKMAQQGYDNLDSENHNLLLCLLMTSADLSDQTKNWRNTRSVAELIYKEFFRQGDLEKAIGNQPAEQMDRERAVVPNLQIAFLDGIVSPLYRVLSLLHPQTDCINHTIERTRENWSKISQKVASHEIKGNSEEIFRNKLVE 2760
+VS LLG +IS E L +S+ AAKILFP ++ HQ S EI++ + + +++ + +++ L +S+I + + +N + +S K++ + F +S NR RL+ + S T S L + +P + IS + N IL+LC SL+D++A +LQ KVL Y+++ T++E GF+++ +DT EL+C G I ++ E + F+++++S+ L Q L I + NA + Q T IQ + LC PV + +++ IA+VCLINK +QFT DE++I ECF++ +L +++AYQNER ++ +TE ML VA+NIF+ M +L LLL IMQEA+NLT+AERCSVFL++ ++N LVAKV DGLPT+ +KN + + DG + P EIR QGIAG+VATTGE+LNIK AY HPLFYRGVD ETGF+T+NILCFPI+++ VGVAQLCNKI FFT+ DE++AK FSIYCCISI HSLMYK V+DAQHR++LANELMMYHM++ ED WLST I ++ FL + SF S+PRN++ + +T + +SMF + LI+RWRI+RRTL +FI MV+R YR P YHNWMHAFSVAHF+++CIKNLPL + QL ++E+ ALFVASLCHDIDHRGTNNSFQVQS S+ AALYSSEGSVLERHHFSQT+C+LNTEGCN+FE++ +++Y + LD IRDIILATDL+HHL+I K+E+++ +GYD SE+H LLLCLLMTSADLSDQTK+W NT VA+LIY+EFF+QGD+EK++G+ P + MDRERA VP+LQI+FLD I++PLY+VL+ L+PQ I TIE +NW I + V +IKGN EIF + L+E
Sbjct: 7 DVSVLLGSIISRREMLEQSQNAAKILFPSCWLAELVISNRHQPSVNCPLEVLIREIRNSTDQEI-SVKEVTTSFINQLASVSKIQNQSNFNTTNNNQH------MISFELNKDNKYGEYAAHFVLSSTLNRIIRLEQF-NEFSSTSSLLKQRYPCCSQGTEASTWISREDNALILKLCESLWDKEANRLQHKVLRYIMERTNSENGFIVMRNIDTSELVCHCTGNEIFDESTYI--ENDSFFNEIMQSRKTFKASQLNSKQEHTLLSILSVRNAYMNNENYITNQNTDIQIHSVLCSPVFTRSSDNPIAVVCLINKRD-SQFTQSDERIIEECFRFVAPILLSSLAYQNERYIRDRTEDMLKVARNIFTHMMDLTNLLLKIMQEAQNLTKAERCSVFLLESETNVLVAKVLDGLPTAPNKNNKPKSYDGPTLFLTLKPYHLSFKLFFMLPEEIRLSLNQGIAGYVATTGELLNIKDAYAHPLFYRGVDKETGFRTRNILCFPIKNEKDGIVGVAQLCNKINHPFFTRADEDVAKTFSIYCCISIVHSLMYKNVQDAQHRTKLANELMMYHMKVDEDRKNWLSTCEIKDINTFLPNTSSFESLPRNIQPENETYLCTLSMFHNLNLINRWRISRRTLAQFILMVRRGYRTPAYHNWMHAFSVAHFVYVCIKNLPLANNQLDDIEILALFVASLCHDIDHRGTNNSFQVQSKSVFAALYSSEGSVLERHHFSQTICVLNTEGCNIFENVSKEDYGQLLDHIRDIILATDLSHHLRIMPKLEELSHRGYDGTKSEDHYLLLCLLMTSADLSDQTKSWNNTVYVAKLIYEEFFQQGDMEKSLGHNPVDSMDRERACVPHLQISFLDYIITPLYKVLNNLYPQCSSILDTIEINSDNWKIILELVEKGDIKGNGSEIFNHNLIE 914
BLAST of Phosphodiesterase vs. TrEMBL
Match: A0A4Z2CVF2 (Phosphodiesterase OS=Schistosoma japonicum OX=6182 GN=EWB00_007250 PE=3 SV=1) HSP 1 Score: 806.594 bits (2082), Expect = 0.000e+0 Identity = 437/870 (50.23%), Postives = 592/870 (68.05%), Query Frame = 1
Query: 169 EVSSLLGVVISYDEFLSKSKYAAKILFPLATAVQM-----HQVS-----EIKHPKIRAM---CTIRRTSFLYVSDLEDLSEIISSGELDILKSNSYDILVIVSVSSSQPKESLILTFFQKFNENSENRSKRLDFLEKQMSLTLSRLMR------------------------IHPNKIISNQINQ-ILELCGSLFDQDAGKLQKKVLSYLIQNTSAETGFLLLVCMDTVELLCQVIGQVIQEDPINFDAEENGIFDKVLKS-KTGINLGCLTEAQ--LREISEIMNAS----------KQETKIQNALCVPVRHQGTNDVIAIVCLINKSGPAQFTNYDEQVINECFKYTTSVLFTTIAYQNERRLKLQTEKMLVVAKNIFSRMDNLNELLLMIMQEARNLTQAERCSVFLVDEDSNELVAKVFDGLPTSSDKNERLRLQDGTEIQQPVEIRFPKAQGIAGHVATTGEMLNIKKAYDHPLFYRGVDDETGFKTKNILCFPIQDDCGKTVGVAQLCNKIKGHFFTKMDEEIAKAFSIYCCISITHSLMYKKVEDAQHRSRLANELMMYHMQIPEDDIAWLSTFSIPPVSIFLSDFESFNSIPRNVK-DRDTLMACISMFDGIGLISRWRINRRTLTKFIFMVKRNYRDPPYHNWMHAFSVAHFIFICIKNLPL-DKQLTELELFALFVASLCHDIDHRGTNNSFQVQSNSILAALYSSEGSVLERHHFSQTVCILNTEGCNVFESLPQKEYXXXXXXXXXXXXXXXXXHHLQIFSKIEKMAQQGYDNLDSENHNLLLCLLMTSADLSDQTKNWRNTRSVAELIYKEFFRQGDLEKAIGNQPAEQMDRERAVVPNLQIAFLDGIVSPLYRVL 2619
+VS LLG +IS E L +S+ AAKILFP ++ HQ S E+ +I + T++ + ++ L +S+ + + +N Y ++ +++ + + F + + + Q+S TL+R++R I + I+ + N+ IL+LC SL+D +LQ KVL YL+Q T++E GF+++ DT EL+C IG I ++ E + +F+++++S KT + +E + L + I NA +E +I + LC PV + + I +VCLINK +QFT DE +I ECF+YT +L ++++ QNER ++ +TE ML VA+NIF+ M +L LLL IMQEA+NLT+AERCSVFL+D ++N LVAKV DGLPT+ +KN DG + P EIR QGIAGHVATTGE+LNIK AY HPLFYRGVD ETGF+T+NILCFPI+++ VGVAQLCNKI FFT+ DE++AK FSIYCCISI HSLMYK V+DAQHR++LANELMMYHM++ ED WLST I ++ FL + SF S+PRN++ + +T + +SMF + LI+RWRI+RRTL +FI MV+R YR+P YHNWMHAF+VAHFI++CIKNLPL +KQL ++E+ ALFVASLCHDIDHRGTNNSFQVQS S+LAALYSSEGSVLERHHFSQT+C+LNT+GCN+FE++ +++Y + LD IRDIILATDL+HHL+I SK+E+M+ +GYD SE+H LLLCLLMTSADLSDQTK W NT VA+LIY+EFF+QGD+EK++G+ P + MDRERA VPNLQI+FLD I+ PLYR++
Sbjct: 17 DVSILLGSIISRREMLEQSQNAAKILFPSCWIAELVISNRHQPSINCPLEVLMREISSSNQEITVKEVTTSFIVHLASVSKNQNMSNFNTKNTNQY--MISFELNNEDKRSDYVAHFVMILESLPKAHLHKAQLFKSQLSCTLNRIIRLEQFNELSSTLSSLKQRYPCCSQGIEASTWINRKDNELILKLCESLWDTQTNRLQHKVLRYLMQRTNSENGFIVMRNTDTSELVCYCIGDEIFDESTYI--ENDSLFNEIMQSGKTFTSTTPNSEQKQVLLSVLSIHNAYMNNEHPITNLHEEMEINSFLCSPVFTRSSEYPIGVVCLINKKD-SQFTQSDEFIIEECFRYTAPILLSSLSCQNERYIRDRTEDMLKVARNIFTHMMDLTNLLLKIMQEAQNLTKAERCSVFLLDSETNVLVAKVLDGLPTAPNKNTHFTTTDGKIVTLPEEIRLSLNQGIAGHVATTGELLNIKDAYAHPLFYRGVDKETGFRTRNILCFPIKNEKDGIVGVAQLCNKINHPFFTRADEDVAKTFSIYCCISIVHSLMYKNVQDAQHRTKLANELMMYHMKVDEDKKNWLSTCEIKDINSFLPNTSSFESLPRNIQPENETYLCTLSMFHNLNLINRWRISRRTLAQFILMVRRGYRNPAYHNWMHAFTVAHFIYVCIKNLPLANKQLEDIEILALFVASLCHDIDHRGTNNSFQVQSKSVLAALYSSEGSVLERHHFSQTICVLNTDGCNIFENVSKEDYSQLLDHIRDIILATDLSHHLRIMSKLEEMSHRGYDVTKSEDHYLLLCLLMTSADLSDQTKPWNNTVYVAKLIYEEFFQQGDMEKSLGHNPIDSMDRERACVPNLQISFLDYIILPLYRLV 881
BLAST of Phosphodiesterase vs. Ensembl Cavefish
Match: pde11a (phosphodiesterase 11a [Source:ZFIN;Acc:ZDB-GENE-070912-207]) HSP 1 Score: 310.457 bits (794), Expect = 1.749e-90 Identity = 191/599 (31.89%), Postives = 329/599 (54.92%), Query Frame = 1
Query: 922 KIQNALCVPVRHQGTNDVIAIVCLINKS-GPAQFTNYDEQVINECFKYTTSVLFTTIAYQNERRLKLQTEKMLVVAKNIFSRMDNLNELLLMIMQEARNLTQAERCSVFLVDEDSNELV--AKVFDGLPTSSDKNERLRLQDGTEIQQPVEIRFPKAQGIAGHVATTGEMLNIKKAYDHPLFYRGVDDETGFKTKNILCFPIQDDCGKTVGVAQLCNKIKGHFFTKMDEEIAKAFSIYCCISITHSLMYKKVEDAQHRSRLANELMMYHMQIPEDDIAWLSTFSIPPVSIFLSDFESFNSIPRNVKDRDTLMACISMFDGIGLISRWRINRRTLTKFIFMVKRNYRDPPYHNWMHAFSVAHFIFICIKNLPLDKQLTELELFALFVASLCHDIDHRGTNNSFQVQSNSILAALYSSEGSVLERHHFSQTVCILNTEGCNVFESLPQKEYXXXXXXXXXXXXXXXXXHHLQIFSKIEKMAQQGYDNLDSENH-NLLLCLLMTSADLSDQTKNWRNTRSVAELIYKEFFRQGDLEKA-IGNQPAEQMDRERA-VVPNLQIAFLDGIVSPLYRVLSLLHPQTDCINHTIERTRENWSKISQK 2700
K ++ LC+P+R+ ++I + INKS G A FT DE+V+ + + + R+ ++ +L V ++F +L +++ IM A+ L + ERCSV L+++ + +V K F+ L + +D E + + IA VA+TG +NI AY P F D +GF +++LC PI + + +GVAQ+ N++ G F D+ + +AF I+C + I +++MY +V+ + + +A +++ YH + ++ +IP V D SF+ +V + A + MF +G++ +++I+ TL +++ V++NYR YHNW HAF+V +F + + L+ELE+ AL V +CHD+DHRGTNN+FQ ++ S L+ LY + + LE HHF+ V IL +EG N+F +L ++Y + L++ ILATDL + + + ++ ++G N + + H ++ +LMT+ DL TK W +R VAEL+ EFF QGD E++ + P+ DR R +P+LQ+ ++DGI SPLY L+ L+P+ + I+ R W ++ Q+
Sbjct: 297 KTKSLLCMPIRN-SDGEIIGVAQAINKSPGGALFTEDDEKVLQMYLPFCGIAISNAQLFAASRKEYDRSRALLEVVNDLFEEQTDLEKIVRKIMHRAQTLLKCERCSVQLLEDIESPVVKFTKSFELLSPKCSADTENSFKDSMEKSSYSDWLINNS--IAELVASTGLPVNISDAYQDPRFDAEADQFSGFHIRSVLCVPIWNSNHQIIGVAQVLNRLDGKPFDDADQRLFEAFVIFCGLGINNTIMYDQVKKSWAKQSVALDVLSYHATCSKTEVDKFKAANIPLVCELGIDKLSFDDFSLDVDA--MITAALRMFMELGMLQKFKIDYETLCRWLLTVRKNYRMVLYHNWRHAFNVCQCMFSLLTTAGFQETLSELEILALIVGCVCHDLDHRGTNNAFQAKTGSALSLLYGTSAT-LEHHHFNHAVMILQSEGHNIFSNLSSRDYGDLMQLLKQSILATDLTLYFENRNSFFELVKKGEYNWNVKEHRDMFRSMLMTACDLGAVTKPWDISRKVAELVTSEFFEQGDRERSELKLTPSAIFDRNRKDELPSLQLEWIDGICSPLYETLAKLNPKLQPMVDVIQANRAKWDELHQR 889 HSP 2 Score: 97.8265 bits (242), Expect = 2.981e-20 Identity = 65/198 (32.83%), Postives = 106/198 (53.54%), Query Frame = 1
Query: 1120 QTEKMLVVAKNIFSRMDNLNELLLMIMQEARNLTQAERCSVFLVDEDSNE--LVAKVFDGLPTSSDKNERLRLQDGTEIQQPV----EIRFPKAQGIAGHVATTGEMLNIKKAYDHPLFYRGVDDETGFKTKNILCFPIQDDCGKTVGVAQLCNKIK-GHFFTKMDEEIAKAFSIYCCISITHSLMYKKVEDAQHRSR 1692
+ E L + K+I + +D L L I+ + A+RCS+FLV+ +N+ LV+K FD + GT + + E++ P +GI G+VA GE +NI AY F +D TG+KTK++LC PI++ G+ +GVAQ NK G FT+ DE++ + + +C I+I+++ ++ RSR
Sbjct: 182 EREFFLELVKDISNDLD-LTSLSYKILVFVCIMVDADRCSLFLVEGTANKKTLVSKFFD-------------VHAGTTVLPSLSNSDEVQVPWGKGIIGYVAEHGETVNIPDAYQDHRFSDEIDKLTGYKTKSLLCMPIRNSDGEIIGVAQAINKSPGGALFTEDDEKVLQMYLPFCGIAISNAQLFAASRKEYDRSR 365
BLAST of Phosphodiesterase vs. Ensembl Cavefish
Match: pde10a (phosphodiesterase 10A [Source:ZFIN;Acc:ZDB-GENE-040426-1115]) HSP 1 Score: 291.582 bits (745), Expect = 2.377e-84 Identity = 205/596 (34.40%), Postives = 314/596 (52.68%), Query Frame = 1
Query: 922 KIQNALCVPVRHQGTNDVIAIVCLINKSGPAQFTNYDEQVINECFKYTTSVLFTTIAYQNERRLKLQTEK---MLVVAKNIFSRMDNLNELLLMIMQEARNLTQAERCSVFLVDEDSNELVAKVFDGLPTSSDKNERLRLQDGTEIQQPVEIRFPKAQGIAGHVATTGEMLNIKKAYDHPLFYRGVDDETGFKTKNILCFPIQDDCGKTVGVAQLCNKIKGHFFTKMDEEIAKAFSIYCCISITHSLMYKKVEDAQHRSRLANELMMYHMQIPEDDIAWLSTFSIP-PVSIFLSDFESFNSIPRNVKDRDTLMACISMFDGIGLISRWRINRRTLTKFIFMVKRNYRDPPYHNWMHAFSVAHFIFICIKNLPLDKQLTELELFALFVASLCHDIDHRGTNNSFQVQSNSILAALYSSEGSVLERHHFSQTVCILNTEGCNVFESLPQKEYXXXXXXXXXXXXXXXXXHHLQIFSKIEKMAQQGYDNLDSENH-NLLLCLLMTSADLSDQTKNWRNTRSVAELIYKEFFRQGDLEKAIGNQPAEQMDRERA-VVPNLQIAFLDGIVSPLYRVLSLLHPQTDCINHTIERTRENWSKI 2691
++ + LC+P+ D+IA++ L G F ++V + + + Q R L QTE +L V+K F + ++ LL IM A+NL A+RC++F VD ++ EL + +FD ++NE + ++ EIRF +GIAG VA TGE+LNI AY P F R VD TG+ T+NILC PI G +GV Q+ NK+ G FTK DE K F+++C +++ + MY ++ ++ R+ E + YH ++ L+ S+P P+ + E F+ ++ + L + ++ + L +F V++NYR PYHNW HA +VAH ++ ++ TELE L +A LCHD+DHRG +NS+ + + LAALYS+ S +E+HHFSQTV IL EG N+F +L EY + L++IR I+ATDLA + +I ++ G +L++ H + ++ L+MT+ DL TK W TR A IY EF+ +GD K IG QP MDR++ VP Q+ F + + P Y L L P + + W KI
Sbjct: 217 RVHSVLCLPIL-TAIGDLIAVLELHRHLGQEPFNLSHQEVATANLAWASVAIHQV---QVCRGLAKQTELNDFLLDVSKTYFDNIVAIDSLLEHIMIYAKNLVNADRCALFQVDHNNKELYSDLFD----IGEENEGKPV-----FRKTKEIRFSIEKGIAGQVARTGEVLNIPDAYADPRFNREVDHYTGYTTRNILCMPIVSR-GTVIGVVQMVNKLSGSAFTKTDENNFKMFAVFCALALHCANMYHRIRHSECIYRVTMEKLSYHSICTSEEWKTLTQLSLPDPI---YKEIELFHF---DISPYEELWPAVFVYMIHNSCGKSSFELEKLCRFTMSVRKNYRRVPYHNWKHAVTVAHCMYAILQK--TSGIFTELEKKGLLIACLCHDLDHRGYSNSYLQKFDHPLAALYST--STMEQHHFSQTVSILQ-EGHNIFSNLTSSEYEQVLEIIRKAIIATDLALYFGNRKQIAELLSTGALDLNNHAHRDRVIGLMMTACDLCSVTKLWPVTRLTANDIYAEFWSEGDEMKKIGMQPIPMMDRDKKDEVPQGQVGFYNAVAIPCYTTLVELFPPSAPLLSACRENLGQWEKI 787
BLAST of Phosphodiesterase vs. Ensembl Cavefish
Match: pde11a (phosphodiesterase 11a [Source:ZFIN;Acc:ZDB-GENE-070912-207]) HSP 1 Score: 290.041 bits (741), Expect = 2.659e-83 Identity = 184/598 (30.77%), Postives = 312/598 (52.17%), Query Frame = 1
Query: 922 KIQNALCVPVRHQGTNDVIAIVCLINKS-GPAQFTNYDEQVINECFKYTTSVLFTTIAYQNERRLKLQTEKMLVVAKNIFSRMDNLNELLLMIMQEARNLTQAERCSVFLVDEDSNELV--AKVFDGLPTSSDKNERLRLQDGTEIQQPVEIRFPKAQGIAGHVATTGEMLNIKKAYDHPLFYRGVDDETGFKTKNILCFPIQDDCGKTVGVAQLCNKIKGHFFTKMDEEIAKAFSIYCCISITHSLMYKKVEDAQHRSRLANELMMYHMQIPEDDIAWLSTFSIPPVSIFLSDFESFNSIPRNVKDRDTLMACISMFDGIGLISRWRINRRTLTKFIFMVKRNYRDPPYHNWMHAFSVAHFIFICIKNLPLDKQLTELELFALFVASLCHDIDHRGTNNSFQVQSNSILAALYSSEGSVLERHHFSQTVCILNTEGCNVFESLPQKEYXXXXXXXXXXXXXXXXXHHLQIFSKIEKMAQQGYDNLDSENHNLLLCLLMTSADLSDQTKNWRNTRSVAELIYKEFFRQGDLEKA-IGNQPAEQMDRERA-VVPNLQIAFLDGIVSPLYRVLSLLHPQTDCINHTIERTRENWSKISQK 2700
K ++ LC+P+R+ ++I + INKS G A FT DE+V+ + + + R+ ++ +L V ++F +L +++ IM A+ L + ERCSV L+++ + +V K F+ L + +D E + + IA VA+TG +NI AY P F D +GF +++LC PI + + +GVAQ+ N++ G F D+ + +AF I+C + I +++MY +V+ + + +A +++ YH + ++ +IP V D SF+ +V + A + MF +G++ +++I+ TL +++ V++NYR YHNW HAF+V +F + + L+ELE+ AL V +CHD+DHRGTNN+FQ ++ S L+ LY + + LE HHF+ V IL +E V L + L + L S E + + Y+ E+ ++ +LMT+ DL TK W +R VAEL+ EFF QGD E++ + P+ DR R +P+LQ+ ++DGI SPLY L+ L+P+ + I+ R W ++ Q+
Sbjct: 275 KTKSLLCMPIRN-SDGEIIGVAQAINKSPGGALFTEDDEKVLQMYLPFCGIAISNAQLFAASRKEYDRSRALLEVVNDLFEEQTDLEKIVRKIMHRAQTLLKCERCSVQLLEDIESPVVKFTKSFELLSPKCSADTENSFKDSMEKSSYSDWLINNS--IAELVASTGLPVNISDAYQDPRFDAEADQFSGFHIRSVLCVPIWNSNHQIIGVAQVLNRLDGKPFDDADQRLFEAFVIFCGLGINNTIMYDQVKKSWAKQSVALDVLSYHATCSKTEVDKFKAANIPLVCELGIDKLSFDDFSLDVDA--MITAALRMFMELGMLQKFKIDYETLCRWLLTVRKNYRMVLYHNWRHAFNVCQCMFSLLTTAGFQETLSELEILALIVGCVCHDLDHRGTNNAFQAKTGSALSLLYGTSAT-LEHHHFNHAVMILQSEVGTV----------NNLQMFMHSRLHSCFKGQLNRNSFFELVKKGEYNWNVKEHRDMFRSMLMTACDLGAVTKPWDISRKVAELVTSEFFEQGDRERSELKLTPSAIFDRNRKDELPSLQLEWIDGICSPLYETLAKLNPKLQPMVDVIQANRAKWDELHQR 856 HSP 2 Score: 97.4413 bits (241), Expect = 3.901e-20 Identity = 65/198 (32.83%), Postives = 106/198 (53.54%), Query Frame = 1
Query: 1120 QTEKMLVVAKNIFSRMDNLNELLLMIMQEARNLTQAERCSVFLVDEDSNE--LVAKVFDGLPTSSDKNERLRLQDGTEIQQPV----EIRFPKAQGIAGHVATTGEMLNIKKAYDHPLFYRGVDDETGFKTKNILCFPIQDDCGKTVGVAQLCNKIKGH-FFTKMDEEIAKAFSIYCCISITHSLMYKKVEDAQHRSR 1692
+ E L + K+I + +D L L I+ + A+RCS+FLV+ +N+ LV+K FD + GT + + E++ P +GI G+VA GE +NI AY F +D TG+KTK++LC PI++ G+ +GVAQ NK G FT+ DE++ + + +C I+I+++ ++ RSR
Sbjct: 160 EREFFLELVKDISNDLD-LTSLSYKILVFVCIMVDADRCSLFLVEGTANKKTLVSKFFD-------------VHAGTTVLPSLSNSDEVQVPWGKGIIGYVAEHGETVNIPDAYQDHRFSDEIDKLTGYKTKSLLCMPIRNSDGEIIGVAQAINKSPGGALFTEDDEKVLQMYLPFCGIAISNAQLFAASRKEYDRSR 343
BLAST of Phosphodiesterase vs. Ensembl Cavefish
Match: pde11al (dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A-like [Source:NCBI gene;Acc:103024879]) HSP 1 Score: 288.115 bits (736), Expect = 2.043e-82 Identity = 191/621 (30.76%), Postives = 324/621 (52.17%), Query Frame = 1
Query: 922 KIQNALCVPVRHQGTNDVIAIVCLINKSGPAQ-FTNYDEQVINECFKYTTSVLFTTIAYQNERRLKLQTEKMLVVAKNIFSRMDNLNELLLMIMQEARNLTQAERCSVFLVDEDSNELV--AKVFDGLPTSSDKNERLRLQDGTEIQQPVEIRFPKAQGIAGHVATTGEMLNIKKAYDHPLFYRGVDDETGFKTKNILCFPIQDDCGKTVGVAQLCNKIKGHFFTKMDEEIAKAFSIYCCISITHSLMYKKVEDAQHRSRLANELMMYHMQIPEDDIAWLSTFSIPPVSIFLSDFESFNSIPRNVKDRDTLMACISMFDGIGLISRWRINRRTLTKFIFMVKRNYRDPPYHNWMHAFSVAHFIFICIKNLPLDKQLTELELFALFVASLCHDIDHRGTNNSFQVQSNSILAALYSSEGSVLERHHFSQTVCILNTEGCNVFESLPQKEYXXXXXXXXXXXXXXXXXHHLQIFSKIEKMAQQGYDNLDSENH-NLLLCLLMTSADLSDQTKNWRNTRSVAELIYKEFFRQGDLEKA-IGNQPAEQMDRERA-VVPNLQIAFLDGIVSPLYRVLSLLHPQTDCINHTIERTRENWSK----------ISQKVASHEIKGNSEE 2736
K Q+ LC+ + + +VI +V INK+ FT DE+V+ + + + R+ ++ +L V ++F +L +++ IMQ A L Q ERCSV L+++ + +V +K F+ + + + ++ + + IA VA+TG +NI P F D +GF +++LC PI + + +GVAQ+ N++ F D+ + +AF I+C + I +++MY +V+ + +A +++ YH + ++ L IP S D FN ++ + + A + MF +G++ +++I+ L +++ V++NYR YHNW HAF+V+ +F+ I + LT+ E AL V LCHD+DHRGTNN+FQ +S S LA LY + + LE HHF+ V IL +EG N+F +L KEY + L++ IL+TDL + Q +K + G + + H ++L +LMT+ DL T+ W ++ VAEL+ EFF QGD E+A + P+ DR R +P LQ+ ++DGI PLY L L+ + + I+ R+ W + IS+ + +++G EE
Sbjct: 272 KTQSILCMAICN-SDGEVIGVVQAINKNPKGTPFTEDDEKVLQMYLPFCGISISNAKLFSESRKEYDRSRALLEVVNDLFEEQTDLEKIVRKIMQRALTLLQCERCSVLLLEDIHSPVVKFSKTFELMSPLCSVDHDISMEKVSCSDWLIN------NSIAELVASTGLPVNISDVCQDPRFDAEADQASGFHIRSVLCVPIWNRTHQIIGVAQILNRLDRKTFNDADQRLFEAFVIFCGLGINNTMMYNQVKKTWAKQSVALDMLSYHATCSKVEVDRLKAAKIPLSSELGIDKFHFNDF--SLDNDAMITASLRMFLELGVVQKFKIDYEVLCRWLLTVRKNYRTVAYHNWRHAFNVSQCMFVMITTAGFQEVLTDTETLALMVGCLCHDLDHRGTNNAFQAKSGSALALLYGTSAT-LEHHHFNHAVMILQSEGHNIFANLCSKEYSHMMQLLKQAILSTDLTLYFQRRTKFFECVLSGEFSWSIQEHRDVLRSMLMTACDLGAVTRPWEISKQVAELVTSEFFEQGDRERAELKLTPSAIFDRNRKDELPALQLEWIDGICKPLYEALVKLNRKLQPMVDGIDANRKKWEELCLSYQQACSISEPSSPCQVEGEGEE 882 HSP 2 Score: 95.1301 bits (235), Expect = 2.085e-19 Identity = 68/205 (33.17%), Postives = 109/205 (53.17%), Query Frame = 1
Query: 1108 RLKLQTEK--MLVVAKNIFSRMDNLNELLLMIMQEARNLTQAERCSVFLVDEDSNE--LVAKVFDGLPTSSDKNERLRLQDGTEIQ-----QPVEIRFPKAQGIAGHVATTGEMLNIKKAYDHPLFYRGVDDETGFKTKNILCFPIQDDCGKTVGVAQLCNK-IKGHFFTKMDEEIAKAFSIYCCISITHSLMYKKVEDAQHRSR 1692
RLK E+ L + K+I + +D N L I+ + A+RCS+FLV+ S++ LV+K FD + GT ++ E++ P +GI G+VA GE +NI AY+ F +D TG+KT++ILC I + G+ +GV Q NK KG FT+ DE++ + + +C ISI+++ ++ + RSR
Sbjct: 150 RLKENNEREFFLELVKDISNELDMTN-LSYKILINVCIMVSADRCSLFLVEGPSHKRTLVSKFFD-------------VHSGTTVRPSSSMNSSEVQVPWGKGIIGYVAEHGETVNIPNAYEDHRFSDEIDKLTGYKTQSILCMAICNSDGEVIGVVQAINKNPKGTPFTEDDEKVLQMYLPFCGISISNAKLFSESRKEYDRSR 340
BLAST of Phosphodiesterase vs. Ensembl Cavefish
Match: pde11al (dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A-like [Source:NCBI gene;Acc:103024879]) HSP 1 Score: 283.108 bits (723), Expect = 4.655e-81 Identity = 184/572 (32.17%), Postives = 304/572 (53.15%), Query Frame = 1
Query: 922 KIQNALCVPVRHQGTNDVIAIVCLINKSGPAQ-FTNYDEQVINECFKYTTSVLFTTIAYQNERRLKLQTEKMLVVAKNIFSRMDNLNELLLMIMQEARNLTQAERCSVFLVDEDSNELV--AKVFDGLPTSSDKNERLRLQDGTEIQQPVEIRFPKAQGIAGHVATTGEMLNIKKAYDHPLFYRGVDDETGFKTKNILCFPIQDDCGKTVGVAQLCNKIKGHFFTKMDEEIAKAFSIYCCISITHSLMYKKVEDAQHRSRLANELMMYHMQIPEDDIAWLSTFSIPPVSIFLSDFESFNSIPRNVKDRDTLM-ACISMFDGIGLISRWRINRRTLTKFIFMVKRNYRDPPYHNWMHAFSVAHFIFICIKNLPLDKQLTELELFALFVASLCHDIDHRGTNNSFQVQSNSILAALYSSEGSVLERHHFSQTVCILNTEGCNVFESLPQKEYXXXXXXXXXXXXXXXXXHHLQIFSKIEKMAQQGYDNLDSENH-NLLLCLLMTSADLSDQTKNWRNTRSVAELIYKEFFRQGDLEKA-IGNQPAEQMDRERA-VVPNLQIAFLDGIVSPLYRV 2616
K Q+ LC+ + + +VI +V INK+ FT DE+V+ + + + R+ ++ +L V ++F +L +++ IMQ A L Q ERCSV L+++ + +V +K F+ + + + ++ + + IA VA+TG +NI P F D +GF +++LC PI + + +GVAQ+ N++ F D+ + +AF I+C + I +++MY +V+ + +A +++ YH + ++ L IP S D FN D D ++ A + MF +G++ +++I+ L +++ V++NYR YHNW HAF+V+ +F+ I + LT+ E AL V LCHD+DHRGTNN+FQ +S S LA LY + + LE HHF+ V IL +EG N+F +L KEY + L++ IL+TDL + Q +K + G + + H ++L +LMT+ DL T+ W ++ VAEL+ EFF QGD E+A + P+ DR R +P LQ+ ++DGI PLY V
Sbjct: 272 KTQSILCMAICN-SDGEVIGVVQAINKNPKGTPFTEDDEKVLQMYLPFCGISISNAKLFSESRKEYDRSRALLEVVNDLFEEQTDLEKIVRKIMQRALTLLQCERCSVLLLEDIHSPVVKFSKTFELMSPLCSVDHDISMEKVSCSDWLIN------NSIAELVASTGLPVNISDVCQDPRFDAEADQASGFHIRSVLCVPIWNRTHQIIGVAQILNRLDRKTFNDADQRLFEAFVIFCGLGINNTMMYNQVKKTWAKQSVALDMLSYHATCSKVEVDRLKAAKIPLSSELGIDKFHFNDFSL---DNDAMITASLRMFLELGVVQKFKIDYEVLCRWLLTVRKNYRTVAYHNWRHAFNVSQCMFVMITTAGFQEVLTDTETLALMVGCLCHDLDHRGTNNAFQAKSGSALALLYGTSAT-LEHHHFNHAVMILQSEGHNIFANLCSKEYSHMMQLLKQAILSTDLTLYFQRRTKFFECVLSGEFSWSIQEHRDVLRSMLMTACDLGAVTRPWEISKQVAELVTSEFFEQGDRERAELKLTPSAIFDRNRKDELPALQLEWIDGICKPLYEV 832 HSP 2 Score: 95.1301 bits (235), Expect = 1.774e-19 Identity = 68/205 (33.17%), Postives = 109/205 (53.17%), Query Frame = 1
Query: 1108 RLKLQTEK--MLVVAKNIFSRMDNLNELLLMIMQEARNLTQAERCSVFLVDEDSNE--LVAKVFDGLPTSSDKNERLRLQDGTEIQ-----QPVEIRFPKAQGIAGHVATTGEMLNIKKAYDHPLFYRGVDDETGFKTKNILCFPIQDDCGKTVGVAQLCNK-IKGHFFTKMDEEIAKAFSIYCCISITHSLMYKKVEDAQHRSR 1692
RLK E+ L + K+I + +D N L I+ + A+RCS+FLV+ S++ LV+K FD + GT ++ E++ P +GI G+VA GE +NI AY+ F +D TG+KT++ILC I + G+ +GV Q NK KG FT+ DE++ + + +C ISI+++ ++ + RSR
Sbjct: 150 RLKENNEREFFLELVKDISNELDMTN-LSYKILINVCIMVSADRCSLFLVEGPSHKRTLVSKFFD-------------VHSGTTVRPSSSMNSSEVQVPWGKGIIGYVAEHGETVNIPNAYEDHRFSDEIDKLTGYKTQSILCMAICNSDGEVIGVVQAINKNPKGTPFTEDDEKVLQMYLPFCGISISNAKLFSESRKEYDRSR 340
BLAST of Phosphodiesterase vs. Ensembl Sea Lamprey
Match: PDE2A (phosphodiesterase 2A [Source:HGNC Symbol;Acc:HGNC:8777]) HSP 1 Score: 650.973 bits (1678), Expect = 0.000e+0 Identity = 315/593 (53.12%), Postives = 435/593 (73.36%), Query Frame = 1
Query: 922 KIQNALCVPVRHQGTNDVIAIVCLINKSGPAQFTNYDEQVINECFKYTTSVLFTTIAYQNERRLKLQTEKMLVVAKNIFSRMDNLNELLLMIMQEARNLTQAERCSVFLVDEDSNELVAKVFDGLPTSSDKNERLRLQDGTEIQQPVEIRFPKAQGIAGHVATTGEMLNIKKAYDHPLFYRGVDDETGFKTKNILCFPIQDDCGKTVGVAQLCNKIKGHFFTKMDEEIAKAFSIYCCISITHSLMYKKVEDAQHRSRLANELMMYHMQIPEDDIAWLSTFSIPPVSIFLSDFESFNSIPRNVKDRDTLMACISMFDGIGLISRWRINRRTLTKFIFMVKRNYRDPPYHNWMHAFSVAHFIFICIKNLPLDKQLTELELFALFVASLCHDIDHRGTNNSFQVQSNSILAALYSSEGSVLERHHFSQTVCILNTEGCNVFESLPQKEYXXXXXXXXXXXXXXXXXHHLQIFSKIEKMAQQGYDNLDSENHNLLLCLLMTSADLSDQTKNWRNTRSVAELIYKEFFRQGDLEKAIGNQPAEQMDRERAVVPNLQIAFLDGIVSPLYRVLSLLHPQTDCINHTIERTRENWSKISQK 2700
++ + L VP+ + T+ V+ + C+ NK +T DE+ I CF +T++VL +TIA+Q E++LK + + +L VAKN+F+ +D+++ LL I+QEARNL+ AERCSVFL+D S+ELVAKVFDG G + E+R P QGIAGHVATTGE+LNIK AY HPLFYRGVDD TGF+T++ILCFPI+D+ + +GVA+LCNKI G +F+K DE++A AFSIYC ISI +SL+YKKV +AQ RS+L+NE+MMYHM++ +++ + I V+ DF F PR++ + T+ A + M + +G I+ ++++ RTLT++ MV++ YRDPPYHNWMHA+SV+HF ++ KNL L K L ++E+FALFV+ LCHD+DHRGTNNSFQV S S+LAALYSSEGSV+ERHHF+Q + I+N+ GCN+ E+L +KEY R LDL+RDIILATDLAHHL+IF + K+A GY+ + H+LLLCLLMTS DLSDQTK W+ TR +AELIYKEFF QGDLEKA+GN+P+E MDRE+A +P LQI+F++ I PL+++L + P + + +E+W ++S K
Sbjct: 8 RVNSMLSVPIVARATSQVVTLACVFNKLHGQSYTETDERKIQHCFCFTSTVLTSTIAFQKEQKLKFECQALLQVAKNLFTHLDDVSVLLHEIIQEARNLSNAERCSVFLLDRSSHELVAKVFDG---------------GVVSDESYEVRIPADQGIAGHVATTGEVLNIKDAYSHPLFYRGVDDSTGFRTRSILCFPIKDENEEVIGVAELCNKINGPWFSKFDEDLATAFSIYCGISIANSLLYKKVAEAQQRSQLSNEMMMYHMKVSPEEMNKVLNSRIQTVTDIHPDFAKFTYTPRSLGEDQTITAILGMVEDMGFINNYKLDLRTLTRWCLMVRKGYRDPPYHNWMHAYSVSHFCYLLYKNLDLGKYLQDMEIFALFVSCLCHDLDHRGTNNSFQVDSKSVLAALYSSEGSVMERHHFAQAIAIINSAGCNILENLSRKEYQRMLDLMRDIILATDLAHHLRIFKDLRKIADAGYNPDNGHQHSLLLCLLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEKAMGNRPSEMMDREKAYIPELQISFMEHIAMPLFKLLKDMLPGAAELYERVAANKEHWMRVSHK 585
BLAST of Phosphodiesterase vs. Ensembl Sea Lamprey
Match: PDE2A (phosphodiesterase 2A [Source:HGNC Symbol;Acc:HGNC:8777]) HSP 1 Score: 447.203 bits (1149), Expect = 9.399e-149 Identity = 228/399 (57.14%), Postives = 300/399 (75.19%), Query Frame = 1
Query: 1168 DNLNELLLMIMQEARNLTQAERCSVFLVDEDSNELVAKVFDGLPTSSDKNERLRLQDGTEIQQPVEIRFPKAQGIAGHVATTGEMLNIKKAYDHPLFYRGVDDETGFKTKNILCFPIQDDCGKTVGVAQLCNKIKGHFFTKMDEEIAKAFSIYCCISITHSLMYKKVEDAQHRSRLANELMMYHMQI-----PEDDIAWLSTFSIPPVSIFLSDFESFNSIPRNVKDRDTLMACISMFDGIGLISRWRINRRTLTKFIFMVKRNYRDPPYHNWMHAFSVAHFIFICIKNLPLDKQLTELELFALFVASLCHDIDHRGTNNSFQVQSNSILAALYSSEGSVLERHHFSQTVCILNTEGCNVFESLPQKEYXXXXXXXXXXXXXXXXXHHLQIFSKIEKMA 2349
D+++ LL I+QEARNL+ AERCSVFL+D S+ELVAKVFDG S E + E+R P QGIAGHVATTGE+LNIK AY HPLFYRGVDD TGF+T++ILCFPI+D+ + +GVA+LCNKI G +F+K DE++A AFSIYC ISI +SL+YKKV +AQ RS+L+NE+MMYHM++ PE+ L++ I V+ DF F PR++ + T+ A + M + +G I+ ++++ RTLT++ MV++ YRDPPYHNWMHA+SV+HF ++ KNL L K L ++E+FALFV+ LCHD+DHRGTNNSFQV S S+LAALYSSEGSV+ERHHF+Q + I+N+ GCN+ E+L +KEY R LDL+RDIILATDLAHHL+IF + K+A
Sbjct: 5 DDVSVLLHEIIQEARNLSNAERCSVFLLDRSSHELVAKVFDGGVVSD------------EFMKSYEVRIPADQGIAGHVATTGEVLNIKDAYSHPLFYRGVDDSTGFRTRSILCFPIKDENEEVIGVAELCNKINGPWFSKFDEDLATAFSIYCGISIANSLLYKKVAEAQQRSQLSNEMMMYHMKVGTQVSPEEMNKVLNS-RIQTVTDIHPDFAKFTYTPRSLGEDQTITAILGMVEDMGFINNYKLDLRTLTRWCLMVRKGYRDPPYHNWMHAYSVSHFCYLLYKNLDLGKYLQDMEIFALFVSCLCHDLDHRGTNNSFQVDSKSVLAALYSSEGSVMERHHFAQAIAIINSAGCNILENLSRKEYQRMLDLMRDIILATDLAHHLRIFKDLRKIA 390
BLAST of Phosphodiesterase vs. Ensembl Sea Lamprey
Match: pde5ab (phosphodiesterase 5A, cGMP-specific, b [Source:ZFIN;Acc:ZDB-GENE-060824-4]) HSP 1 Score: 243.432 bits (620), Expect = 5.021e-68 Identity = 189/621 (30.43%), Postives = 318/621 (51.21%), Query Frame = 1
Query: 922 KIQNALCVPVRHQGTNDVIAIVCLINKSG--PAQFTNYDEQVINECFKYTTSVLFTTIAYQNERRLKLQTEKMLVVAKNIFSRMDNLNELLLMIMQEARNLTQAERCSVFLVDEDSNELVAKVFDGLPTSSDKNERLRLQDGTEIQQPVEIR-FPKAQGIAGHVATTGEMLNIKKAYDHPLFYRGVDDETGFKTKNILCFPIQD-DCGKTVGVAQLCNKIK---GHF--FTKMDEEIAKAFSIYCCISITHSLMYKKVEDAQHRSRLANELMMYHMQIPEDDIA-----WLSTFSIPPV-SIFLSDFESFNSIPRNVKDRDTLMACISMFDGIGLISRWRINRRTLTKFIFMVKRNYR-DPPYHNWMHAFSVAHFIFICIKNLPLDKQLTELELFALFVASLCHDIDHRGTNNSF-QVQSNSILAALYSSEGSVLERHHFSQTVCILNTEGCNVFESLPQKEYXXXXXXXXXXXXXXXXXHHLQIFSKIEKMAQQGYDNLDSENH-NLLLCLLMTSADLSDQTKNWRNTRSVAELIYKEFFRQGDLEK-AIGNQPAEQMDRE-RAVVPNLQIAFLDGIVSPLYRVLSLLHPQTDCINHTIERTRENWSKISQKVASHEIKG 2724
K Q+ LC+P++ +++ + INK G +FT DE+ + VL Y++ + + +L +A + +L EL+ I+ + +RC+VF+ D+DS + ++VF ++ L + E E R P + A V +LNI + F V++ ++TK++LC PIQ+ + +GV QL NK++ G F + DE+ +AF+I+C ++I ++ MY+ V A + + E++ YH ED+ A L+T S+P S+ L DF +F+ + + T + + M + L+ + I ++I V++NYR + YHNW HAF+ +F + LT LE+ L +A+L HD+DHRG NNS+ + +S+ LA LY S+LE HHF Q + +LN+ G + SL +EY A+ +I IL+TDLA + + + + + NL+ ++H LL ++MT+ D+S TK W + +AEL+ EFF QGD E+ + +P + M+RE R +P +Q+ F+DGI PLY LS + P + + R+NW K++ +KG
Sbjct: 216 KTQSVLCLPIK-DNKGEIVGVAQAINKKGNNEGKFTEKDEREFGAYLAFCGIVLHNAQLYEDSLLENRRNQVLLELASLVCEEQSSLEELVGRIIDIILSFMPCQRCAVFIADKDSPNIFSRVF---------HKSLEVPGVAENTSQSESRSHPVSFIYAEFVMKMLTLLNIPDVHRDNRFNLPVEERGDYRTKSLLCAPIQNRKKNEVIGVCQLVNKLEEGAGEVRPFNRNDEQFVEAFAIFCGMAIRNTRMYEAVARAVAKQTVTLEVLSYHAIAHEDECAKLQSQHLTTTSVPSAQSLNLLDF-TFSDF--GMAEELTAVGSLRMLLDLSLLQTFSIPNEVACRWILSVRKNYRRNIAYHNWRHAFNTGQCMFTVLVTGQAQNVLTPLEMLCLIIAALSHDLDHRGFNNSYIKNRSDHPLATLYGH--SMLEHHHFDQCLMLLNSPGNEMLSSLSVQEYRSAVGMIEHAILSTDLATYCKNRGEFFSLVKDRTFNLEDQHHRKLLRAMMMTACDVSAITKPWPVQQKIAELVASEFFDQGDRERQELHVEPTDMMNREKRDKIPTIQVGFIDGICLPLYEALSCVFPACAPLLSGCQSNRQNWEKLTTSPQGTIVKG 821 HSP 2 Score: 100.138 bits (248), Expect = 9.888e-22 Identity = 66/187 (35.29%), Postives = 103/187 (55.08%), Query Frame = 1
Query: 1120 QTEKMLVVAKNIFSRMDNLNELLLMIMQEARNLTQAERCSVFLVDEDSNE---LVAKVFDGLPTSSDKNERLRLQDGTEIQQPVEIRFPKAQGIAGHVATTGEMLNIKKAYDHPLFYRGVDDETGFKTKNILCFPIQDDCGKTVGVAQLCNKIKGH---FFTKMDEEIAKAFSIYCCISITHSLMYK 1662
+ E+ L + K+I R+D + L I+ + A+RCS+F+V EDS++ LV+ +FD + L E + +R +GI G+VA TG +NI AY P F VD TG+KT+++LC PI+D+ G+ VGVAQ NK KG+ FT+ DE A+ +C I + ++ +Y+
Sbjct: 102 ERERFLELVKDIACRLDVVT-LCHRILLHVNQVLTADRCSLFIVREDSSQERCLVSTLFD-----------VSLGSTPEQARTSWLRLAWGKGIVGYVAATGNGVNIPNAYQDPRFNVEVDLMTGYKTQSVLCLPIKDNKGEIVGVAQAINK-KGNNEGKFTEKDEREFGAYLAFCGIVLHNAQLYE 275
BLAST of Phosphodiesterase vs. Ensembl Sea Lamprey
Match: pde10a (phosphodiesterase 10A [Source:ZFIN;Acc:ZDB-GENE-040426-1115]) HSP 1 Score: 140.198 bits (352), Expect = 1.057e-35 Identity = 115/388 (29.64%), Postives = 180/388 (46.39%), Query Frame = 1
Query: 592 ISNQINQILELCGSLFDQDAGKLQKKVLSYLIQNTSAETGFLLLVCMDTVELLCQVI------GQ--VIQEDPINFDAEENGIFDKVLKSKTGINLGCLTEAQLREISEIMNAS-KQETKIQNALCVPVRHQGTNDVIAIVCLINKSGPAQFTNYDEQVINECFKYTTSVLFTTIAYQNERRLKLQTEK---MLVVAKNIFSRMDNLNELLLMIMQEARNLTQAERCSVFLVDEDSNELVAKVFDGLPTSSDKNERLRLQDGTEIQQPVEIRFPKAQGIAGHVATTGEMLNIKKAYDHPLFYRGVDDETGFKTKNILCFPIQDDCGKTVGVAQLCNKIKGHFFTKMDEEIAKAFSIYCCISITHSLMYKKVEDAQHRSRLANELMMYH 1719
+++ I Q L++ G KL L Y+I N + GF L + LC GQ +I P+ F A + KV ++ L E L + ++++ LC+P+ D++ ++ L + G FT ++V + + + Q L QTE +L V+K F + ++ LL IM A+NL A+RC++F VD +NEL + +FD +K + + EI RF +GIAG VA TG +LNI AY P F R VD TG+ T+NILC PI G +GV Q+ NK+ G FTK DE K F+++C +++ + MY ++ ++ R+ E + YH
Sbjct: 25 LNSHIEQRLDMGGD------SKLLLHELCYIIHNATNADGFSLYFLGECNNSLCLFTPTGAKEGQQRLIPAGPVGFGATVSAYVAKVRQT-------VLVEDILGDERFPQGVGLDPGAQVRSVLCLPLI-TANGDLLGVLELQRRWGKEPFTIRHQEVATALLAWASVAIHQV---QVSHGLAKQTELNDFLLDVSKTYFDNIVAIDSLLEHIMIYAKNLVNADRCALFQVDHKNNELYSDLFD---IGEEKEGQPVFRKTKEIT----CRFSIEKGIAGQVAKTGMVLNIPDAYADPRFNREVDLYTGYTTRNILCMPIVSR-GSVIGVVQMVNKLSGSAFTKTDENNFKMFAVFCALALHCANMYHRIRHSECIFRVTLEKLSYH 387
BLAST of Phosphodiesterase vs. Ensembl Sea Lamprey
Match: pde1a (phosphodiesterase 1A, calmodulin-dependent [Source:ZFIN;Acc:ZDB-GENE-090831-2]) HSP 1 Score: 119.783 bits (299), Expect = 2.270e-28 Identity = 82/250 (32.80%), Postives = 133/250 (53.20%), Query Frame = 1
Query: 1879 LISRWRINRRTLTKFIFMVKRNY--RDPPYHNWMHAFSVAHFIFICIKNLPLDKQLTELELFALFVASLCHDIDHRGTNNSFQVQSNSILAALYSSEGSVLERHHFSQTVCILNTEGCNVFESLPQKEYXXXXXXXXXXXXXXXXXHHLQIFSKIEKMAQQGYDNLDSENHNLLLCLLMTSADLSDQTKNWRNTRSVAELIYKEFFRQGDLEKAIGNQPAEQMDRERAVVPNLQIAFLDGIVSPLYRVLS 2622
LISR++I L F+ ++ Y PYHN HA V + + L L+ELE A+ A+ HD++H GT N+F +Q+ S +A LY ++ +VLE HH S ++ + N+F +L + ++ L+ +++LATD++ H Q ++ QQ +S + + + LL+ + D+S TK W + E + +EFFRQGD E +G + DR +V QI F+D IV P + VL+
Sbjct: 182 LISRYKIPVAALVSFVEALEAGYSKHKNPYHNLAHAADVTQTVHYLLLQSGLMHWLSELETLAVIFAAAIHDLEHTGTTNNFHIQTRSDVALLY-NDRAVLENHHVSAAYRLMQDDDMNIFINLSKDDWRELRALVVEMVLATDMSCHFQQIKTMKSALQQP----ESIDKSKAMSLLLHAGDISHPTKEWPLHQRWTEALMEEFFRQGDREAKLGLPFSPLCDRNSTMVAQSQIGFMDFIVEPTFSVLT 426
BLAST of Phosphodiesterase vs. Ensembl Nematostella
Match: EDO38644 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SC93]) HSP 1 Score: 458.373 bits (1178), Expect = 1.420e-151 Identity = 242/491 (49.29%), Postives = 333/491 (67.82%), Query Frame = 1
Query: 1234 CSVFLVDEDSNELVAKVFDG-LPTSSDKNERLRLQDGTEIQQPVEIRFPKAQGIAGHVATTGEMLNIKKAYDHPLFYRGVDDETGFKTKNILCFPIQDDCGKTVGVAQLCNKIKGHFFTKMDEEIAKAFSIYCCISITHSLMYKKVEDAQHRSRLANELMMYHMQIPEDDIAWLSTFSIP-PVSIFLSDFESFNSIPRNVKDRDTLMACISMFDGIGLISRWRINRRTLTKFIFMVKRNYRDPPYHNWMHAFSVAHFIFICIKNLPLDKQLTELELFALFVASLCHDIDHRGTNNSFQVQSNSILAALYSSEGSVLERHHFSQTVCILNTEGCNVFESLPQKEYXXXXXXXXXXXXXXXXXHHLQIFSKIEKMAQQGYDNLDSENHNLLLCLLMTSADLSDQTKNWRNTRSVAELIYKEFFRQGDLEKAIGNQPAEQMDRERAVVPNLQIAFLDGIVSPLYRVLSLLHPQTDCINHTIERTRENWSKISQK 2700
CS+FL+D + +ELVAKVFDG +P++ Q ++R P QGI G VA TG++LNIK AY HPLFYRG+D +TGFKT+NILCFPI+DD G +GVA+LCNK G FTK DE++ +AF+IYC ISI HS++YK+ A HRS++ +ELM+YHM + E+++ L+ I P F+ F+ PR ++ +T+ A + MFD +G+I RW+I R TL +F MV++ YRDPPYHNW HAF+VAHF ++ +KN ++ +L ++E ALFVA LCHD+DHRGTNN+FQV SNS LAALYSSEGSV+ERHHF+QTVCILN+ GCN+F++L + E+ + LDLIR IILATDL+HHL+I I MA +G + + E L+ ++ + DLS + ++ ++A+ K EK +G P E MDRERA +P LQI FL+ I P+Y+VL L P+T + T+ + E W I +K
Sbjct: 1 CSLFLLDRERDELVAKVFDGEIPSN---------------QASRDLRIPTNQGIVGQVAMTGKLLNIKDAYTHPLFYRGLDVKTGFKTRNILCFPIKDDDG-VIGVAELCNKANGKCFTKFDEDLTRAFAIYCGISIFHSMLYKRAATAWHRSQVCSELMIYHMHVSEEELQRLTAHEISSPDEEIPHGFDKFSFAPRTIQMEETVRAALYMFDDLGIIDRWKIPRDTLIRFTLMVRKGYRDPPYHNWTHAFTVAHFCYLLLKNSHMESKLQDIERMALFVACLCHDLDHRGTNNAFQVSSNSTLAALYSSEGSVMERHHFAQTVCILNSSGCNIFKNLTESEFEKVLDLIRYIILATDLSHHLRILKDINNMA-KGRNKNEFEKVLDLIRYIILATDLSHHLRILKDINNMAKGRNKNV--PSLFEKVMGFTPMEMMDRERACIPKLQIDFLENIALPVYKVLHELLPETKEVIDTVHKNMECWQAIEEK 472
BLAST of Phosphodiesterase vs. Ensembl Nematostella
Match: EDO39522 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S9Q1]) HSP 1 Score: 359.377 bits (921), Expect = 1.554e-109 Identity = 225/611 (36.82%), Postives = 346/611 (56.63%), Query Frame = 1
Query: 937 LCVPVR-HQGTNDVIAIVCLINKSGPA---QFTNYDEQVINECFKYTTSVLFTTIAYQNER---RLKLQTEK---MLVVAKNIFSRMDNLNELLLMIMQEARNLTQAERCSVFLVDEDSNELVAKVFDGLPTSSDKNERLRLQDGTEIQQPVEIRFPKAQGIAGHVATTGEMLNIKKAYDHPLFYRGVDDETGFKTKNILCFPIQDDCGKTVGVAQLCNKIKGHFFTKMDEEIAKAFSIYCCISITHSLMYKKVEDAQHRSRLANELMMYHMQIPEDDIAWLSTFSIPPV-SIFLSDFESFNSIPRNVKDRDTLMACISMFDGIGLISRWRINRRTLTKFIFMVKRNYRDPPYHNWMHAFSVAHFIFICIKNLPLDKQLTELELFALFVASLCHDIDHRGTNNSFQVQSNSILAALYSSEGSVLERHHFSQTVCILNTEGCNVFESLPQKEYXXXXXXXXXXXXXXXXXHHLQ----IFSKIEKMAQQGYDNLDSENHNLLLCLLMTSADLSDQTKNWRNTRSVAELIYKEFFRQGDLEK-AIGNQPAEQMDRERA-VVPNLQIAFLDGIVSPLYRVLSLLHPQTDCINHTIERTRENWSKISQKVASHEI 2718
LC+P++ H G +VI + +INK+G + FT DEQ+ KY ++F I N R +L+ + +L +A+ IF +L+ ++ IM ++L Q ERCSV LVD S L A+ FD + + L+ D + VE+RFP GI GHVATTGE LNI AY F VD +GF TK ILC PI++ G +GV QL NK+ G F K DE + +AF+I+C ++I ++MY+ V A + ++A E++ YH P ++ L +PP+ S+ L DF +F+ + ++ D DTL C++M + ++ ++I+ TL +F+ +K+NYR YHNW HAF+VA ++ +K + K T +E +AL VA L HD+DHRGTNNSFQ++S + LA LYS+ S +E HHF Q + I+N++G +F +L EY + + L+ I+ATDLA + Q F K+E + D D + +LL ++MT+ DLS TK W + A L+ +EFF+QGDLE+ + + P MDR + +P +Q+ F+D + PLY+ S + R W K+++ + E+
Sbjct: 238 LCMPIKDHDG--EVIGVAQVINKTGKSTDSAFTIDDEQIF---LKY---LVFCGIGINNAELYERAQLEIRRNQVLLDLARTIFEEQTSLHNIVHKIMMITQSLLQCERCSVLLVDPTSKTLFAQAFD-----LEAKDYLQNDDD---DKTVEVRFPINIGITGHVATTGETLNIPDAYADERFDPTVDQVSGFTTKTILCMPIKNASGDIIGVVQLLNKVDGTPFNKNDENLFEAFAIFCGMAIHSTVMYENVNKAMAKRKVALEVLSYHAVSPLEEAIKLKEEPLPPITSLRLIDF-AFDDM--SISDDDTLKGCLAMLCDLKIVETFQIDYLTLCRFVLTIKKNYRPVMYHNWRHAFNVAQTMYAMLKKPSIGKYFTVIEQYALIVACLSHDLDHRGTNNSFQIKSATPLAQLYST--STMEHHHFDQCIMIINSQGNEIFNTLSADEYNKIIKLLEASIIATDLALYFQRRGDFFKKVE---NRELDWSDDSSKDLLRAMMMTACDLSAITKPWLVQKRTAHLVAEEFFQQGDLEQEELHSTPLPTMDRRKKDELPQMQVGFIDAVCLPLYKAFSQFDDNLKVLKDGCRENRRQWQKLAEDHKAREV 824
BLAST of Phosphodiesterase vs. Ensembl Nematostella
Match: EDO44626 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RVE3]) HSP 1 Score: 330.487 bits (846), Expect = 3.965e-101 Identity = 209/578 (36.16%), Postives = 317/578 (54.84%), Query Frame = 1
Query: 919 TKIQNALCVPVRHQGTNDVIAIVCLINKSGPAQFTNYDEQVINECFKYTTSVLFTTIAYQNERRLKLQTEKMLVVAKNIFSRMDNLNELLLMIMQEARNLTQAERCSVFLVDEDSNELVAKVFDGLPTSSDKNERLRLQDGTEIQQPVEIRFPKAQGIAGHVATTGEMLNIKKAYDHPLFYRGVDDETGFKTKNILCFPIQDDCGKTVGVAQLCNKIKGHFFT--KMDEEIAKAFSIYCCISITHSLMYKKVEDAQHRSRLANELMMYHMQIPEDDIAWLSTFSIPPVSIFLSDFESFNSIPRNVKDRDTLMACISMFDGIGLISRWRINRRTLTKFIFMVKRNYRDPPYHNWMHAFSVAHFIFICIKNLPLDKQLTELELFALFVASLCHDIDHRGTNNSFQVQSNSILAALYSSEGSVLERHHFSQTVCILNTEGCNVFESLPQKEYXXXXXXXXXXXXXXXXXHHLQIFSKIEKMAQQGYDNLDSENH-NLLLCLLMTSADLSDQTKNWRNTRSVAELIYKEFFRQGDLEKAIGNQPAEQMDRERA-VVPNLQIAFLDGIVSPLYRVLSLLHPQT 2640
T Q+ LC P+ Q +++ + L G F DE+V N + L+ Y + + + TE +L V ++IF + +++ +++ IM A+ L A+R S+FLVD +NEL A++FD + L+D Q EIRFPK +G+AG+VAT+GE LNI AY F R +D +TG+ T+ +LC PI G +GV Q+ NK G DE+ + F+IYC +++ H+ +Y K+ ++ + R+A E++ YH + E ++ L P L +E F+S + + +M + +F L S R + L +F+ V++NYR PYHNW HAF+VAH +++ I++ T LE A+F A LCHD+DHRG NS+ + LAA+YS+ S +E HHF+QT+ IL EG N+F L EY L +++ ILATDLA +K++ + +G + D + H LL + MT+ DLS TK WR + E+IY+EF+ +GDLEKA G QP DR A +P Q+ FL GI P Y +L + P T
Sbjct: 51 TTAQSILCQPIV-QSNGELVGTIELSRMVGRDPFDEEDEEVFNSYLVWGGISLYYAEMYLHMHKHRKLTEFLLNVTRSIFQDIVSMDTVIMKIMNYAQTLVDADRTSLFLVDNKTNELYARIFDIGGS---------LEDSRSSQLQKEIRFPKTKGVAGYVATSGETLNISDAYHDDRFNREIDIQTGYTTRTLLCMPIFIR-GNIIGVVQMVNKKSGVLIMCFSSDEKSFQTFAIYCGLALHHAKLYDKIRRSEQKHRVALEVLSYHSKCSEGELHRLKELDCPDPYPDLETYE-FDSYSLDSE----VMPKLVIFQTRNLFSLSRFDLDELYRFVLTVRKNYRKVPYHNWTHAFAVAHCMYLVIRS--GHNNFTGLEALAMFFACLCHDLDHRGRTNSWMKNEGTPLAAVYST--STMEHHHFNQTITILQHEGHNIFSQLNSAEYKTVLGYMKECILATDLALFFGNKAKLKDVVDKGTFSWDDQEHRRLLRAICMTACDLSACTKPWRIQYKIVEVIYQEFYAEGDLEKAQGKQPIPMKDRNTAHELPAHQVGFLVGICLPCYELLGKVIPGT 608
BLAST of Phosphodiesterase vs. Ensembl Nematostella
Match: EDO32088 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SW30]) HSP 1 Score: 291.197 bits (744), Expect = 8.101e-87 Identity = 199/577 (34.49%), Postives = 308/577 (53.38%), Query Frame = 1
Query: 919 TKIQNALCVPVRHQGTNDVIAIVCLINKSGPAQFTNYDEQVINECFKY-TTSVLFTTIAYQNERRLKLQTEKMLVVAKNIFSRMDNLNELLLMIMQEARNLTQAERCSVFLVDEDSNELVAKVFDGLPTSSDKNERLRLQDGTEIQQPVEIRFPKAQGIAGHVATTGEMLNIKKAYDHPLFYRGVDDETGFKTKNILCFPIQDDC-GKTVGVAQLCNKIKGHFFTKMDEEIAKAFSIYCCISITHSLMYKKVEDAQHRSRLANELMMYHMQIPEDDIAWLSTFSIPPVSIFLSDFESFNSIPRNVKDRDTLMACISMFDGIGLISRWRINRRTLTKFIFMVKRNYRDPPYHNWMHAFSVAHFIFICIKNLPLDKQLTELELFALFVASLCHDIDHRGTNNSFQVQSNSILAALYSSEGSVLERHHFSQTVCILNTEGCNVFESLPQKEYXXXXXXXXXXXXXXXXXHHLQIFSKIEKMAQQGYDNLDSENH-NLLLCLLMTSADLSDQTKNWRNTRSVAELIYKEFFRQGDLEKAIGNQPAEQMDRERA-VVPNLQIAFLDGIVSPLYRVLSLLHPQ 2637
T + LC P+ Q ++ +V L+ G F DE+++N + + ++ I+ Q ++ L T +L V ++IF + ++ ++ IM A+ L A+RCS+FL+D+ S EL A +FD D NE + G EI RFP ++GIAG+VA TG +LNI+ AY F R VD +TG+ T ILC P++ C G +GV Q+ N G FF+ D + + F+ YC +++ +S MY + AQ + ++A E++ YH E + FL+ + P S + + +R++ T+ +F V++ YRD PYHNW HAFSVAH ++I I++ +K LT+ E +LF+A +CHD+DHRG NN+F + + LA LY++ S +E HHF Q V IL +EG NVF L + Y R L+LI++ I+ATDL ++E + + + E H +L+ CLLMT+ DL K W +++EF+ QGD E+ +G P MDR + +P Q+ FL GIV P Y +L P+
Sbjct: 56 TTAMSVLCQPII-QSDGTLVGVVELVKALGSMPFEKEDEEILNSYLVWGSIAIHHAEISKQITKQKDLNT-FLLNVVRSIFDEVCTMDTVIEKIMAFAKKLVNADRCSLFLLDQASEELFANLFD------DGNEDGSFRCGNEI------RFPVSKGIAGYVACTGSILNIRDAYRDERFNREVDMKTGYTTHTILCVPVR--CKGSIIGVCQMVNSHNG-FFSPNDMQSFEMFAGYCGLALHYSKMYNSLFCAQQKHQVALEVISYHCCASEKE-----------TEEFLNSADLVMLPPAYYP--------FSYLSALIFVLIFRVDLETIARFSLSVRKCYRDIPYHNWCHAFSVAHSLWIVIRD---NKSLTDYEKLSLFIAGICHDVDHRGKNNAFMLHCKTPLANLYTT--STMEWHHFKQGVFILESEGQNVFGQLDAESYRRVLELIQEAIIATDLMLFFGNKKELETLQENKAFRWEEEKHRSLIRCLLMTACDLCTSAKPWDIQVVAVNKVFEEFYIQGDEERKMGLDPLPMMDRSKHDDLPENQVGFLKGIVRPCYSLLMDFVPE 591 HSP 2 Score: 57.3806 bits (137), Expect = 2.564e-8 Identity = 35/106 (33.02%), Postives = 53/106 (50.00%), Query Frame = 1
Query: 1351 QQPVEIRFPKAQGIAGHVATTGEMLNIKKAYDHPLFYRGVDDETGFKTKNILCFPIQDDCGKTVGVAQLCNKIKGHFFTKMDEEIAKAFSIYCCISITHSLMYKKV 1668
+QP+ K +A HVA TGE L IK F +G+ E ++LC PI G VGV +L + F K DEEI ++ ++ I+I H+ + K++
Sbjct: 15 RQPI----GKGGTVAAHVAETGERLFIKDILGDERFPKGIGVEGMTTAMSVLCQPIIQSDGTLVGVVELVKALGSMPFEKEDEEILNSYLVWGSIAIHHAEISKQI 116
BLAST of Phosphodiesterase vs. Ensembl Nematostella
Match: EDO43657 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RY89]) HSP 1 Score: 258.07 bits (658), Expect = 1.271e-73 Identity = 186/597 (31.16%), Postives = 317/597 (53.10%), Query Frame = 1
Query: 937 LCVPVRHQGTNDVIAIVCLINKS-GPAQFTNYDEQVINECFKYTTSVLFTTIAYQNERRLKL------QTEKMLVVAKNIFSRMDNLNELLLMIMQEARNLTQAERCSVFLVDEDSNELVAKVFDGLPTSSDKNERLRLQDGTEIQQPVEIRFPKAQGIAGHVATTGEMLNIKKA-YDHPLFYRGVDDETGFKTKNILCFPIQDDCGKTVGVAQLCNKIKGHFFTKMDEEIAKAFSIYCCISITHSLMYKKVEDAQHRSRLANELMMYHMQIPEDDIAWLSTFSIP-PVSIFLSDFESFNSIPRNVKDRDTLMACISMFDGIGLISRWRINRRTLTKFIFMVKRNYRDPPYHNWMHAFSVAHFIFICIKNLPLDKQLTELELFALFVASLCHDIDHRGTNNSFQVQSNSILAALYSSEGSVLERHHFSQTVCILNTEGCNVFESLPQKEYXXXXXXXXXXXXXXXXXHHLQIFSKIEKMAQQG-YDNLDSENHNLLLCLLMTSADLSDQTKNWRNTRSVAELIYKEFFRQGDLEKAIGN-QPAEQMDRERA-VVPNLQIAFLDGIVSPLYRVLSLLHPQTDCINHTIERTRENWSKI 2691
LC PV++ +V+ + +INK+ G FT DE+V C Y T F I N + +L + +L + +IF +L +++ IM+ A L + E+CSV L+ + ++VF+ L T+ R + +A VA TG+ +NI A D L ++ GF ILC PI+++ + +GVA+L N++ F + DE + +AF+I+C + I ++++Y ++ A+ + ++A E++ YH+ + ++ + +P V I L F+ F+ ++ D L+A + MF G I + I+ L+++I VK NYR+ YHNW HAF+VA +F + + +T+LE L V LCHD+DHRGTNN+FQ +++S L+ LY + S LE HHF+ V IL+TEG F + EY + + I+ IL+TDLA + + K + + G +D + ++ ++L ++MT+ DL+ TK W + V L+ +EFF QGD+E+ N +P MDR++ +P LQ+ F + P+++VL+ L+ + + E + W K+
Sbjct: 140 LCKPVKNN-EGEVVGVAQIINKNPGGVPFTKEDEKV---CDMYLT---FCGIGITNAKLFELSAIEFNRNRALLELVHDIFEEQTSLEKVVHKIMKRALGLLKCEKCSVLLLTQPELRF-SRVFN-LKTTGRITSNTRYGFILLLVSEGHNDRSFTSRVAKLVAATGKTMNIPDASQDTRLADSSNVEKKGFSP--ILCMPIRNNKFEIIGVAELINRLDNKPFDENDETLFEAFAIFCGLGIHNTMIYDQMARAKAKQQVALEVLSYHVAAKKTEVEKIRDTQVPKAVDINLHSFK-FDDF--SLAADDMLIASLRMFKDCGFIEEFHIDYEVLSRWILTVKNNYRNVIYHNWRHAFNVAQSMFCMLTTGGMASVITKLECLGLIVGCLCHDLDHRGTNNAFQAKTDSPLSKLYGT--STLEHHHFNHAVIILSTEG---FSPILSDEYRQVISYIKHSILSTDLATNFKQRPKFFALVESGEFDPYNMDHRDMLKAMMMTACDLNGTTKPWEIQKEVVNLVTREFFEQGDMERERYNMEPMAIMDRQKIDELPKLQVQFFETTGLPVFKVLAKLNNKLQPLVDGAESNKRRWQKL 717 HSP 2 Score: 108.997 bits (271), Expect = 2.670e-24 Identity = 72/197 (36.55%), Postives = 109/197 (55.33%), Query Frame = 1
Query: 1141 VAKNIFSRMDNLNELLLMIMQEARNLTQAERCSVFLVDEDSNE--LVAKVFD----GLPTSSDKNERLRLQDGTEIQQPVEIRFPKAQGIAGHVATTGEMLNIKKAYDHPLFYRGVDDETGFKTKNILCFPIQDDCGKTVGVAQLCNKIKGHF-FTKMDEEIAKAFSIYCCISITHSLMYKKVEDAQHRSRLANELM 1710
+ ++I + +D L L I+ LT A+RCS+FLV+ + LV+KVFD L SS K I EIR P G+ G+ A TGE +NI AY P F + VD +TG+ TK++LC P++++ G+ VGVAQ+ NK G FTK DE++ + +C I IT++ +++ +R+R EL+
Sbjct: 23 IVRDIANDLD-LKTLSYKILVNVGILTNADRCSLFLVEGPKGKQWLVSKVFDVHIGSLNVSSAKEA---------IDHQREIRVPLGVGLVGYAAETGETVNIPDAYADPRFNQDVDKQTGYHTKSLLCKPVKNNEGEVVGVAQIINKNPGGVPFTKEDEKVCDMYLTFCGIGITNAKLFELSAIEFNRNRALLELV 209
BLAST of Phosphodiesterase vs. Ensembl Medaka
Match: pde11a (phosphodiesterase 11A [Source:NCBI gene;Acc:101163533]) HSP 1 Score: 298.516 bits (763), Expect = 3.950e-86 Identity = 188/602 (31.23%), Postives = 320/602 (53.16%), Query Frame = 1
Query: 922 KIQNALCVPVRHQGTNDVIAIVCLINKSGPAQ-FTNYDEQVINECFKYTTSVLFTTIAYQNERRLKLQTEKMLVVAKNIFSRMDNLNELLLMIMQEARNLTQAERCSVFLVDEDSNELV--AKVFDGLPTSSDKNERLRLQDGTEIQQPVEIRFPKAQGIAGHVATTGEMLNIKKAYDHPLFYRGVDDETGFKTKNILCFPIQDDCGKTVGVAQLCNKIKGHFFTKMDEEIAKAFSIYCCISITHSLMYKKVEDAQHRSRLANELMMYHMQIPEDDIAWLSTFSIPPVSIFLSDFESFNSIPRNVKDRDTLMACISMFDGIGLISRWRINRRTLTKFIFMVKRNYRDPPYHNWMHAFSVAHFIFICIKNLPLDKQLTELELFALFVASLCHDIDHRGTNNSFQVQSNSILAALYSSEGSVLERHHFSQTVCILNTEGCNVFESLPQKEYXXXXXXXXXXXXXXXXXHHLQIFSKIEKMAQQGYDNLDSENH-NLLLCLLMTSADLSDQTKNWRNTRSVAELIYKEFFRQGDLEK-AIGNQPAEQMDRERA-VVPNLQIAFLDGIVSPLYRVLSLLHPQTDCINHTIERTRENWSKISQKVAS 2709
K ++ LC+P+ H ++I + INK+ + FT DE+V+ + + + R+ ++ +L V ++F +L +++ IM A+ L + ERCSV L+++ + +V K F+ L + +D E + IA VA+TG +NI AY P F D + F +++LC PI + + +GVAQ+ N++ G F D+ + +AF I+C + I +++MY +V+ + + +A +++ YH + ++ +IP V D SF+ +V + A + MF +G++ +++I+ TL +++ V++NYR YHNW HAF+V +F + + LT+LE+ AL V +CHD+DHRGTNN+FQ ++ S LA LY + + LE HHF+ V IL +EG N+F +L EY + L++ ILATDL + + + + +G N + + H ++ ++MT+ DL TK W +R VAEL+ EFF QGD E+ + P+ DR R +P LQ+ ++DGI +PLY L L+P+ + I R W ++++K S
Sbjct: 278 KTKSLLCMPI-HNSDGEIIGVAQAINKTSNGELFTEDDEKVLQMYLPFCGIAISNAQLFAASRKEYDRSRALLEVVNDLFEEQTDLEKIVRKIMHRAQTLLKCERCSVQLLEDIESPVVRFTKSFELLSPKCSADAESSFKDSMEKSSYSDWLI--NNRIAELVASTGLPVNISDAYQDPRFDAEADQFSDFHIRSVLCVPIWNSNHQIIGVAQVLNRLDGKPFDDADQRLFEAFVIFCGLGINNTIMYDQVKKSWAKQSVALDVLSYHATCSKTEVDKFKAANIPLVCELGIDKLSFDDFSLDVDA--MITAALRMFMELGMVQKFKIDYETLCRWLLTVRKNYRMVLYHNWRHAFNVCQCMFAMLTTAGFQEVLTDLEILALIVGCVCHDLDHRGTNNAFQAKTGSALALLYGTSAT-LEHHHFNHAVMILQSEGHNIFSNLSSTEYSDLMQLLKLSILATDLTLYFENRNMFFDLVSKGEYNWNVKAHRDMCRSMMMTACDLGAVTKPWDISRKVAELVTSEFFEQGDRERLELKLTPSAIFDRNRKDELPGLQLEWIDGICAPLYETLVKLNPKLQPMFDRIRANRSKWEELNKKRQS 873 HSP 2 Score: 97.8265 bits (242), Expect = 2.768e-20 Identity = 65/197 (32.99%), Postives = 103/197 (52.28%), Query Frame = 1
Query: 1120 QTEKMLVVAKNIFSRMDNLNELLLMIMQEARNLTQAERCSVFLVDEDSNE--LVAKVFDGLPTSSDKNERLRLQDGTEI---QQPVEIRFPKAQGIAGHVATTGEMLNIKKAYDHPLFYRGVDDETGFKTKNILCFPIQDDCGKTVGVAQLCNKIK-GHFFTKMDEEIAKAFSIYCCISITHSLMYKKVEDAQHRSR 1692
+ E L + K+I + +D L L I+ + A+RCS+FLV+ N+ LV+K FD + GT + E++ P +GI G+VA GE +NI AY F +D TG+KTK++LC PI + G+ +GVAQ NK G FT+ DE++ + + +C I+I+++ ++ RSR
Sbjct: 164 EREFFLELVKDISNDLD-LTSLSYKILVFVCIMVDADRCSLFLVEGTGNKKTLVSKFFD-------------VHAGTTVLISMNSDEVQVPWGKGIIGYVAEHGETVNIPDAYQDRRFSDEIDKLTGYKTKSLLCMPIHNSDGEIIGVAQAINKTSNGELFTEDDEKVLQMYLPFCGIAISNAQLFAASRKEYDRSR 346
BLAST of Phosphodiesterase vs. Ensembl Medaka
Match: pde10a (phosphodiesterase 10A [Source:NCBI gene;Acc:101162470]) HSP 1 Score: 293.893 bits (751), Expect = 1.601e-85 Identity = 198/597 (33.17%), Postives = 316/597 (52.93%), Query Frame = 1
Query: 922 KIQNALCVPVRHQGTNDVIAIVCLINKSGPAQFTNYDEQVINECFKYTTSVLFTTIAYQNERRLKLQTEK---MLVVAKNIFSRMDNLNELLLMIMQEARNLTQAERCSVFLVDEDSNELVAKVFDGLPTSSDKNERLRLQDGTEIQQPVEIRFPKAQGIAGHVATTGEMLNIKKAYDHPLFYRGVDDETGFKTKNILCFPIQDDCGKTVGVAQLCNKIKGHFFTKMDEEIAKAFSIYCCISITHSLMYKKVEDAQHRSRLANELMMYHMQIPEDDIAWLSTFSIPPVSIFLSDFESFNSIPRNVKDRDTLMACISMFDGIGLISRWRINRRTLTKFIFMVKRNYRDPPYHNWMHAFSVAHFIFICIKNLPLDKQLTELELFALFVASLCHDIDHRGTNNSFQVQSNSILAALYSSEGSVLERHHFSQTVCILNTEGCNVFESLPQKEYXXXXXXXXXXXXXXXXXHHLQIFSKIEKMAQQGYDNLDSENH-NLLLCLLMTSADLSDQTKNWRNTRSVAELIYKEFFRQGDLEKAIGNQPAEQMDRERA-VVPNLQIAFLDGIVSPLYRVLSLLHPQTDCINHTIERTRENWSKISQ 2697
++ + LC+P+ D++AI+ L G F ++V + + + Q R L QTE +L V+K F + ++ LL IM A+NL A+RC++F VD ++ EL + +FD +K + ++ EIRF +GIAG VA TGE+LNI AY P F R VD +TG+ T+NILC PI G +GV Q+ NK+ G FTK DE K F+++C +++ + MY ++ ++ R+ E + YH ++ L+ ++P + + E+F ++ + + + ++ L +F V++NYR PYHNW HA +VAH ++ ++ P TELE L +A LCHD+DHRG +N++ + + LAALYS+ S +E+HHFSQTV IL EG N+F +L EY + L++IR I+ATDLA + ++ ++ + ++ +H + ++ L+MT+ DL TK W+ TR A IY EF+ +GD K IG QP MDR++ VP Q+ F + + P Y LS L P + + +W +I++
Sbjct: 194 RVHSVLCLPIV-TAIGDLVAILELRRHWGKEPFNLSHQEVATANLAWASVAIHQV---QVCRGLAKQTELNDFLLDVSKTYFDNIVAIDSLLEHIMIYAKNLVNADRCALFQVDHNNKELYSDLFD---IGEEKEGK------PVFRKTKEIRFSIDKGIAGQVARTGEVLNIPDAYADPRFNREVDLKTGYTTRNILCMPIVSR-GTVIGVVQMVNKLCGSAFTKTDENNFKMFAVFCALALHCANMYHRIRHSECIYRVTMEKLSYHSICTSEEWKTLTQLNLP--TPIYKEIETFQF---DISPFEEIWPAVFIYMVHNSCGENSFELEKLCRFTMSVRKNYRRVPYHNWKHAVTVAHCMYAILQKTP--DSFTELEKKGLLIACLCHDLDHRGYSNAYLQKFDHPLAALYST--STMEQHHFSQTVSILQLEGHNIFSNLNSSEYEQVLEIIRKAIIATDLALYFNNHQQLTELLSTSALDFNNHSHRDRVIGLMMTACDLCSVTKQWQITRLTANDIYAEFWAEGDEMKKIGIQPIPMMDRDKKDEVPEGQVGFYNSVAIPCYTTLSKLFPPSSPLLKACRENLSHWERIAR 767
BLAST of Phosphodiesterase vs. Ensembl Medaka
Match: pde10a (phosphodiesterase 10A [Source:NCBI gene;Acc:101162470]) HSP 1 Score: 293.893 bits (751), Expect = 1.666e-85 Identity = 199/598 (33.28%), Postives = 318/598 (53.18%), Query Frame = 1
Query: 922 KIQNALCVPVRHQGTNDVIAIVCLINKSGPAQFTNYDEQVINECFKYTTSVLFTTIAYQNERRLKLQTEK---MLVVAKNIFSRMDNLNELLLMIMQEARNLTQAERCSVFLVDEDSNELVAKVFDGLPTSSDKNERLRLQDGTEI-QQPVEIRFPKAQGIAGHVATTGEMLNIKKAYDHPLFYRGVDDETGFKTKNILCFPIQDDCGKTVGVAQLCNKIKGHFFTKMDEEIAKAFSIYCCISITHSLMYKKVEDAQHRSRLANELMMYHMQIPEDDIAWLSTFSIPPVSIFLSDFESFNSIPRNVKDRDTLMACISMFDGIGLISRWRINRRTLTKFIFMVKRNYRDPPYHNWMHAFSVAHFIFICIKNLPLDKQLTELELFALFVASLCHDIDHRGTNNSFQVQSNSILAALYSSEGSVLERHHFSQTVCILNTEGCNVFESLPQKEYXXXXXXXXXXXXXXXXXHHLQIFSKIEKMAQQGYDNLDSENH-NLLLCLLMTSADLSDQTKNWRNTRSVAELIYKEFFRQGDLEKAIGNQPAEQMDRERA-VVPNLQIAFLDGIVSPLYRVLSLLHPQTDCINHTIERTRENWSKISQ 2697
++ + LC+P+ D++AI+ L G F ++V + + + Q R L QTE +L V+K F + ++ LL IM A+NL A+RC++F VD ++ EL + +FD +K +G + ++ EIRF +GIAG VA TGE+LNI AY P F R VD +TG+ T+NILC PI G +GV Q+ NK+ G FTK DE K F+++C +++ + MY ++ ++ R+ E + YH ++ L+ ++P + + E+F ++ + + + ++ L +F V++NYR PYHNW HA +VAH ++ ++ P TELE L +A LCHD+DHRG +N++ + + LAALYS+ S +E+HHFSQTV IL EG N+F +L EY + L++IR I+ATDLA + ++ ++ + ++ +H + ++ L+MT+ DL TK W+ TR A IY EF+ +GD K IG QP MDR++ VP Q+ F + + P Y LS L P + + +W +I++
Sbjct: 197 RVHSVLCLPIV-TAIGDLVAILELRRHWGKEPFNLSHQEVATANLAWASVAIHQV---QVCRGLAKQTELNDFLLDVSKTYFDNIVAIDSLLEHIMIYAKNLVNADRCALFQVDHNNKELYSDLFD---IGEEK-------EGKPVFRKTKEIRFSIDKGIAGQVARTGEVLNIPDAYADPRFNREVDLKTGYTTRNILCMPIVSR-GTVIGVVQMVNKLCGSAFTKTDENNFKMFAVFCALALHCANMYHRIRHSECIYRVTMEKLSYHSICTSEEWKTLTQLNLP--TPIYKEIETFQF---DISPFEEIWPAVFIYMVHNSCGENSFELEKLCRFTMSVRKNYRRVPYHNWKHAVTVAHCMYAILQKTP--DSFTELEKKGLLIACLCHDLDHRGYSNAYLQKFDHPLAALYST--STMEQHHFSQTVSILQLEGHNIFSNLNSSEYEQVLEIIRKAIIATDLALYFNNHQQLTELLSTSALDFNNHSHRDRVIGLMMTACDLCSVTKQWQITRLTANDIYAEFWAEGDEMKKIGIQPIPMMDRDKKDEVPEGQVGFYNSVAIPCYTTLSKLFPPSSPLLKACRENLSHWERIAR 770
BLAST of Phosphodiesterase vs. Ensembl Medaka
Match: pde10a (phosphodiesterase 10A [Source:NCBI gene;Acc:101162470]) HSP 1 Score: 294.278 bits (752), Expect = 2.355e-85 Identity = 199/598 (33.28%), Postives = 318/598 (53.18%), Query Frame = 1
Query: 922 KIQNALCVPVRHQGTNDVIAIVCLINKSGPAQFTNYDEQVINECFKYTTSVLFTTIAYQNERRLKLQTEK---MLVVAKNIFSRMDNLNELLLMIMQEARNLTQAERCSVFLVDEDSNELVAKVFDGLPTSSDKNERLRLQDGTEI-QQPVEIRFPKAQGIAGHVATTGEMLNIKKAYDHPLFYRGVDDETGFKTKNILCFPIQDDCGKTVGVAQLCNKIKGHFFTKMDEEIAKAFSIYCCISITHSLMYKKVEDAQHRSRLANELMMYHMQIPEDDIAWLSTFSIPPVSIFLSDFESFNSIPRNVKDRDTLMACISMFDGIGLISRWRINRRTLTKFIFMVKRNYRDPPYHNWMHAFSVAHFIFICIKNLPLDKQLTELELFALFVASLCHDIDHRGTNNSFQVQSNSILAALYSSEGSVLERHHFSQTVCILNTEGCNVFESLPQKEYXXXXXXXXXXXXXXXXXHHLQIFSKIEKMAQQGYDNLDSENH-NLLLCLLMTSADLSDQTKNWRNTRSVAELIYKEFFRQGDLEKAIGNQPAEQMDRERA-VVPNLQIAFLDGIVSPLYRVLSLLHPQTDCINHTIERTRENWSKISQ 2697
++ + LC+P+ D++AI+ L G F ++V + + + Q R L QTE +L V+K F + ++ LL IM A+NL A+RC++F VD ++ EL + +FD +K +G + ++ EIRF +GIAG VA TGE+LNI AY P F R VD +TG+ T+NILC PI G +GV Q+ NK+ G FTK DE K F+++C +++ + MY ++ ++ R+ E + YH ++ L+ ++P + + E+F ++ + + + ++ L +F V++NYR PYHNW HA +VAH ++ ++ P TELE L +A LCHD+DHRG +N++ + + LAALYS+ S +E+HHFSQTV IL EG N+F +L EY + L++IR I+ATDLA + ++ ++ + ++ +H + ++ L+MT+ DL TK W+ TR A IY EF+ +GD K IG QP MDR++ VP Q+ F + + P Y LS L P + + +W +I++
Sbjct: 225 RVHSVLCLPIV-TAIGDLVAILELRRHWGKEPFNLSHQEVATANLAWASVAIHQV---QVCRGLAKQTELNDFLLDVSKTYFDNIVAIDSLLEHIMIYAKNLVNADRCALFQVDHNNKELYSDLFD---IGEEK-------EGKPVFRKTKEIRFSIDKGIAGQVARTGEVLNIPDAYADPRFNREVDLKTGYTTRNILCMPIVSR-GTVIGVVQMVNKLCGSAFTKTDENNFKMFAVFCALALHCANMYHRIRHSECIYRVTMEKLSYHSICTSEEWKTLTQLNLP--TPIYKEIETFQF---DISPFEEIWPAVFIYMVHNSCGENSFELEKLCRFTMSVRKNYRRVPYHNWKHAVTVAHCMYAILQKTP--DSFTELEKKGLLIACLCHDLDHRGYSNAYLQKFDHPLAALYST--STMEQHHFSQTVSILQLEGHNIFSNLNSSEYEQVLEIIRKAIIATDLALYFNNHQQLTELLSTSALDFNNHSHRDRVIGLMMTACDLCSVTKQWQITRLTANDIYAEFWAEGDEMKKIGIQPIPMMDRDKKDEVPEGQVGFYNSVAIPCYTTLSKLFPPSSPLLKACRENLSHWERIAR 798
BLAST of Phosphodiesterase vs. Ensembl Medaka
Match: pde5ab (phosphodiesterase 5A [Source:NCBI gene;Acc:101173207]) HSP 1 Score: 255.373 bits (651), Expect = 2.237e-71 Identity = 199/612 (32.52%), Postives = 321/612 (52.45%), Query Frame = 1
Query: 922 KIQNALCVPVR-HQGTNDVIAIVCLINKS--GPAQFTNYDEQVINECFKYTTSVLFTTIAYQNERRLKLQTEKMLVVAKNIFSRMDNLNELLLMIMQEARNLTQAERCSVFLVDEDSNELVAKVFDGLPTSSDKNERLR--LQDGTEIQQPVEIRFPKAQGIAGHVATTGEMLNIKKAYDHPLFYRGVD--DETGFKTKNILCFPIQD-DCGKTVGVAQLCNKI---KGHF--FTKMDEEIAKAFSIYCCISITHSLMYKKVEDAQHRSRLANELMMYHMQIPEDDIAWLSTFSIPPV-SIFLSDFESFNSIPRNVKDRDTLMACISMFDGIGLISRWRINRRTLTKFIFMVKRNYRDP-PYHNWMHAFSVAHFIFICIKNLPLDKQLTELELFALFVASLCHDIDHRGTNNSFQVQSNSILAALYSSEGSVLERHHFSQTVCILNTEGCNVFESLPQKEYXXXXXXXXXXXXXXXXXHHL---QIFSKIEKMAQQGYDNLDSENHNLLLCLLMTSADLSDQTKNWRNTRSVAELIYKEFFRQGDLEKAIGN-QPAEQMDRE-RAVVPNLQIAFLDGIVSPLYRVLSLLHPQTDCINHTIERTRENWSKISQ 2697
K Q+ LC+P++ H+G +V+ + INK+ FT D++ + ++ VL Y+ + + +L +A IF L LL I + QA+ C+VF+ DE+S + VF ++E L L+D +I + AQ +V +T + LNI F D D + K++LC PI++ K +GV QL NK+ G F + DE+ +AF+I+C + I ++ MY+ VE A + + E++ YH E++ L ++P S+ L DF SF+ ++ D +T +A I MF + L+ +++ +L ++I VK+NYR YHNW HAF+ A +F +K+ L L++LE+ AL +A+L HD+DHRG NNS+ +S LA LY S +E HHF Q + ILNT G + L EY L +I ILATDLA ++ + F ++ K Q + +D + +LL +LMT+ D+S TK W + VAEL+ EFF QGD E+ N +P + M+RE R +P++Q++F+D I LY L+ L + ++ R++W ++++
Sbjct: 243 KTQSILCLPIKNHRG--EVVGVAQAINKTCGEDGAFTEQDQKDFSAYLAFSGIVLHNAQLYETSQLENKRNRVLLDLATLIFEEQQCLEVLLRKIAGTILSFMQAQACTVFIADEESMNSFSGVFHM------EHEELSEVLEDPKRNCDVKQINYMFAQ----YVKSTMQPLNISDVTKDQRFPWTSDCPDHMSNQIKSLLCAPIRNRKKDKVIGVCQLVNKLDEASGSIKSFNRNDEQFLEAFAIFCGLGIQNTQMYETVERAMAKQEVTLEVLSYHASATEEESQELQVATVPSAQSLRLLDF-SFSDF--DLSDTETTLATIRMFTDLNLVQNFQMKYTSLCQWILSVKKNYRKSVAYHNWRHAFNTAQCMFALLKSGRLQNNLSDLEILALMIATLSHDLDHRGVNNSYIQRSEHPLAQLYCH--STMEHHHFDQCLMILNTPGNQILSGLSLDEYKATLKMIEKAILATDLALYMKKREDFFELTKNNQ--FVWVDEHHRDLLRSMLMTACDISAITKPWPVQKRVAELVATEFFEQGDKERRELNIEPTDLMNREKRDKIPSMQVSFIDAICIQLYETLAGLLEHCSPLLEGCQKNRQHWKRLAE 835 HSP 2 Score: 97.8265 bits (242), Expect = 2.487e-20 Identity = 78/243 (32.10%), Postives = 130/243 (53.50%), Query Frame = 1
Query: 1129 KMLVVAKNIFSRMDNLNELLLMIMQEARNLTQAERCSVFLVDEDSNE---LVAKVFDGLPTSSDKNERLRLQDGTEIQQPVE--IRFPKAQGIAGHVATTGEMLNIKKAYDHPLFYRGVDDETGFKTKNILCFPIQDDCGKTVGVAQLCNKIKGH--FFTKMDEEIAKAFSIYCCISITHSLMYK--KVEDAQHRSRLANELMMYH----MQIPEDDIAW--LSTFSIPPVSIFLSDFESFNS 1812
++L + K++ S +D + L I L A+R S+FLV EDS+ LV+++FD + +G+ +++ IR +GI GHVA TG+ LNIK AY P F VD TG+KT++ILC PI++ G+ VGVAQ NK G FT+ D++ A+ + I + ++ +Y+ ++E+ ++R L +++ +++ IA LS ++F++D ES NS
Sbjct: 132 RLLELVKDVSSHLD-VPALCHKIFLHINELIAADRYSLFLVGEDSSNRKFLVSRLFD-------------VAEGSTLEESSSSSIRLEWNKGIVGHVAATGQPLNIKNAYKDPRFNAEVDLITGYKTQSILCLPIKNHRGEVVGVAQAINKTCGEDGAFTEQDQKDFSAYLAFSGIVLHNAQLYETSQLENKRNRVLLDLATLIFEEQQCLEVLLRKIAGTILSFMQAQACTVFIADEESMNS 360
BLAST of Phosphodiesterase vs. Planmine SMEST
Match: SMESG000021196.1 (SMESG000021196.1) HSP 1 Score: 1729.92 bits (4479), Expect = 0.000e+0 Identity = 851/857 (99.30%), Postives = 854/857 (99.65%), Query Frame = 1
Query: 163 AQEVSSLLGVVISYDEFLSKSKYAAKILFPLATAVQMHQVSEIKHPKIRAMCTIRRTSFLYVSDLEDLSEIISSGELDILKSNSYDILVIVSVSSSQPKESLILTFFQKFNENSENRSKRLDFLEKQMSLTLSRLMRIHPNKIISNQINQILELCGSLFDQDAGKLQKKVLSYLIQNTSAETGFLLLVCMDTVELLCQVIGQVIQEDPINFDAEENGIFDKVLKSKTGINLGCLTEAQLREISEIMNASKQETKIQNALCVPVRHQGTNDVIAIVCLINKSGPAQFTNYDEQVINECFKYTTSVLFTTIAYQNERRLKLQTEKMLVVAKNIFSRMDNLNELLLMIMQEARNLTQAERCSVFLVDEDSNELVAKVFDGLPTSSDKNERLRLQDGTEIQQPVEIRFPKAQGIAGHVATTGEMLNIKKAYDHPLFYRGVDDETGFKTKNILCFPIQDDCGKTVGVAQLCNKIKGHFFTKMDEEIAKAFSIYCCISITHSLMYKKVEDAQHRSRLANELMMYHMQIPEDDIAWLSTFSIPPVSIFLSDFESFNSIPRNVKDRDTLMACISMFDGIGLISRWRINRRTLTKFIFMVKRNYRDPPYHNWMHAFSVAHFIFICIKNLPLDKQLTELELFALFVASLCHDIDHRGTNNSFQVQSNSILAALYSSEGSVLERHHFSQTVCILNTEGCNVFESLPQKEYXXXXXXXXXXXXXXXXXHHLQIFSKIEKMAQQGYDNLDSENHNLLLCLLMTSADLSDQTKNWRNTRSVAELIYKEFFRQGDLEKAIGNQPAEQMDRERAVVPNLQIAFLDGIVSPLYRVLSLLHPQTDCINHTIERTRENWSKISQKVASHEIKGNSE 2733
AQEVSSLLGVVISYDEFLSKSKYA KILFPLATAVQMHQVSEIKHPKIRAMCTIRRTSFLYVSDLEDLSEIISSGELDILKSNSYDILVIVSVSSSQPKESL+LTFFQKFNENSENRSKRLDFLEKQMSLTLSRLMRIHPNKIISNQINQILELCGSLFDQDAGKLQKKVLSYLIQNTSAETGFLLLVCMDTVELLCQVIGQVIQEDPINFDAEENGIFDKVLKSKTGINLGCLTEAQLREISEIMNASKQETKIQNALCVPVRHQGTNDVIAIVCLINKSGPAQFTNYDEQVINECFKYTTSVLFTTIAYQNERRLKLQTEKMLVVAKNIFSRMDNLNELLLMIMQEARNLTQAERCSVFLVDEDSNELVAKVFDGLPTSSDKNERLRLQDGTEIQQPVEIRFPKAQGIAGHVATTGEMLNIKKAYDHPLFYRGVDDETGFKTKNILCFPIQDDCGKTVGVAQLCNKIKGHFFTKMDEEIAKAFSIYCCISITHSLMYKKVEDAQHRSRLANELMMYHMQIPEDDIAWLSTFSIPPVSIFLSDFESFNSIPRNVKDRDTLMACISMFDGIGLISRWRINRRTLTKFIFMVKRNYRDPPYHNWMHAFSVAHFIFICIKNLPLDKQLTELELFALFVASLCHDIDHRGTNNSFQVQSNSILAALYSSEGSVLERHHFSQTVCILNTEGCNVFESLPQKEYI+ALDLIRDIILATDLAHHLQIFSKIEKMAQQGYDNLDSENHNLLLCLLMTSADLSDQTKNWRNTRSVAELIYKEFFRQGDLEKAIGNQPAEQMDRERAVVPNLQIAFLDGIVSPLYRVLSLLHPQTDCINHTIERTRENWSKISQKVASHEIK +E
Sbjct: 21 AQEVSSLLGVVISYDEFLSKSKYAVKILFPLATAVQMHQVSEIKHPKIRAMCTIRRTSFLYVSDLEDLSEIISSGELDILKSNSYDILVIVSVSSSQPKESLLLTFFQKFNENSENRSKRLDFLEKQMSLTLSRLMRIHPNKIISNQINQILELCGSLFDQDAGKLQKKVLSYLIQNTSAETGFLLLVCMDTVELLCQVIGQVIQEDPINFDAEENGIFDKVLKSKTGINLGCLTEAQLREISEIMNASKQETKIQNALCVPVRHQGTNDVIAIVCLINKSGPAQFTNYDEQVINECFKYTTSVLFTTIAYQNERRLKLQTEKMLVVAKNIFSRMDNLNELLLMIMQEARNLTQAERCSVFLVDEDSNELVAKVFDGLPTSSDKNERLRLQDGTEIQQPVEIRFPKAQGIAGHVATTGEMLNIKKAYDHPLFYRGVDDETGFKTKNILCFPIQDDCGKTVGVAQLCNKIKGHFFTKMDEEIAKAFSIYCCISITHSLMYKKVEDAQHRSRLANELMMYHMQIPEDDIAWLSTFSIPPVSIFLSDFESFNSIPRNVKDRDTLMACISMFDGIGLISRWRINRRTLTKFIFMVKRNYRDPPYHNWMHAFSVAHFIFICIKNLPLDKQLTELELFALFVASLCHDIDHRGTNNSFQVQSNSILAALYSSEGSVLERHHFSQTVCILNTEGCNVFESLPQKEYIKALDLIRDIILATDLAHHLQIFSKIEKMAQQGYDNLDSENHNLLLCLLMTSADLSDQTKNWRNTRSVAELIYKEFFRQGDLEKAIGNQPAEQMDRERAVVPNLQIAFLDGIVSPLYRVLSLLHPQTDCINHTIERTRENWSKISQKVASHEIKDQTE 877 HSP 2 Score: 73.1738 bits (178), Expect = 7.409e-13 Identity = 42/84 (50.00%), Postives = 44/84 (52.38%), Query Frame = 2
Query: 2771 IRDQTENKSHNHCD*Y*KFISISNNRFSLNFHLGTSRFFVLSFALLIIYKFVAVFDFSRDFKRVFYAVGAIGSCSHRVSTNSPI 3022
I+DQTENKSHNH LI + VFDFSRDF RVF AVGAIGSCSHRVSTNSPI
Sbjct: 872 IKDQTENKSHNH--------------------------------FLIFILELRVFDFSRDFNRVFCAVGAIGSCSHRVSTNSPI 923
BLAST of Phosphodiesterase vs. Planmine SMEST
Match: SMESG000021196.1 (SMESG000021196.1) HSP 1 Score: 1698.72 bits (4398), Expect = 0.000e+0 Identity = 840/857 (98.02%), Postives = 843/857 (98.37%), Query Frame = 1
Query: 163 AQEVSSLLGVVISYDEFLSKSKYAAKILFPLATAVQMHQVSEIKHPKIRAMCTIRRTSFLYVSDLEDLSEIISSGELDILKSNSYDILVIVSVSSSQPKESLILTFFQKFNENSENRSKRLDFLEKQMSLTLSRLMRIHPNKIISNQINQILELCGSLFDQDAGKLQKKVLSYLIQNTSAETGFLLLVCMDTVELLCQVIGQVIQEDPINFDAEENGIFDKVLKSKTGINLGCLTEAQLREISEIMNASKQETKIQNALCVPVRHQGTNDVIAIVCLINKSGPAQFTNYDEQVINECFKYTTSVLFTTIAYQNERRLKLQTEKMLVVAKNIFSRMDNLNELLLMIMQEARNLTQAERCSVFLVDEDSNELVAKVFDGLPTSSDKNERLRLQDGTEIQQPVEIRFPKAQGIAGHVATTGEMLNIKKAYDHPLFYRGVDDETGFKTKNILCFPIQDDCGKTVGVAQLCNKIKGHFFTKMDEEIAKAFSIYCCISITHSLMYKKVEDAQHRSRLANELMMYHMQIPEDDIAWLSTFSIPPVSIFLSDFESFNSIPRNVKDRDTLMACISMFDGIGLISRWRINRRTLTKFIFMVKRNYRDPPYHNWMHAFSVAHFIFICIKNLPLDKQLTELELFALFVASLCHDIDHRGTNNSFQVQSNSILAALYSSEGSVLERHHFSQTVCILNTEGCNVFESLPQKEYXXXXXXXXXXXXXXXXXHHLQIFSKIEKMAQQGYDNLDSENHNLLLCLLMTSADLSDQTKNWRNTRSVAELIYKEFFRQGDLEKAIGNQPAEQMDRERAVVPNLQIAFLDGIVSPLYRVLSLLHPQTDCINHTIERTRENWSKISQKVASHEIKGNSE 2733
AQEVSSLLGVVISYDEFLSKSKYA KILFPLATAVQMHQVSEIKHPKIRAMCTIRRTSFLYVSDLEDLSEIISSGELDILKSNSYDILVIVSVSSSQPKESL+LTFFQKFNENSENRSKRLDFLEKQMSLTLSRLMRIHPNKIISNQINQILELCGSLFDQDAGKLQKKVLSYLIQNTSAETGFLLLVCMDTVELLCQVIGQVIQEDPINFDAEENGIFDKVLKSKTGINLGCLTEAQLREISEIMNASKQETKIQNALCVPVRHQGTNDVIAIVCLINKSGPAQFTNYDEQVINECFKYTTSVLFTTIAYQNERRLKLQTEKMLVVAKNIFSRMDNLNELLLMIMQEARNLTQAERCSVFLVDEDSNELVAKVFDGLPTSSDKNE QPVEIRFPKAQGIAGHVATTGEMLNIKKAYDHPLFYRGVDDETGFKTKNILCFPIQDDCGKTVGVAQLCNKIKGHFFTKMDEEIAKAFSIYCCISITHSLMYKKVEDAQHRSRLANELMMYHMQIPEDDIAWLSTFSIPPVSIFLSDFESFNSIPRNVKDRDTLMACISMFDGIGLISRWRINRRTLTKFIFMVKRNYRDPPYHNWMHAFSVAHFIFICIKNLPLDKQLTELELFALFVASLCHDIDHRGTNNSFQVQSNSILAALYSSEGSVLERHHFSQTVCILNTEGCNVFESLPQKEYI+ALDLIRDIILATDLAHHLQIFSKIEKMAQQGYDNLDSENHNLLLCLLMTSADLSDQTKNWRNTRSVAELIYKEFFRQGDLEKAIGNQPAEQMDRERAVVPNLQIAFLDGIVSPLYRVLSLLHPQTDCINHTIERTRENWSKISQKVASHEIK +E
Sbjct: 21 AQEVSSLLGVVISYDEFLSKSKYAVKILFPLATAVQMHQVSEIKHPKIRAMCTIRRTSFLYVSDLEDLSEIISSGELDILKSNSYDILVIVSVSSSQPKESLLLTFFQKFNENSENRSKRLDFLEKQMSLTLSRLMRIHPNKIISNQINQILELCGSLFDQDAGKLQKKVLSYLIQNTSAETGFLLLVCMDTVELLCQVIGQVIQEDPINFDAEENGIFDKVLKSKTGINLGCLTEAQLREISEIMNASKQETKIQNALCVPVRHQGTNDVIAIVCLINKSGPAQFTNYDEQVINECFKYTTSVLFTTIAYQNERRLKLQTEKMLVVAKNIFSRMDNLNELLLMIMQEARNLTQAERCSVFLVDEDSNELVAKVFDGLPTSSDKNE-----------QPVEIRFPKAQGIAGHVATTGEMLNIKKAYDHPLFYRGVDDETGFKTKNILCFPIQDDCGKTVGVAQLCNKIKGHFFTKMDEEIAKAFSIYCCISITHSLMYKKVEDAQHRSRLANELMMYHMQIPEDDIAWLSTFSIPPVSIFLSDFESFNSIPRNVKDRDTLMACISMFDGIGLISRWRINRRTLTKFIFMVKRNYRDPPYHNWMHAFSVAHFIFICIKNLPLDKQLTELELFALFVASLCHDIDHRGTNNSFQVQSNSILAALYSSEGSVLERHHFSQTVCILNTEGCNVFESLPQKEYIKALDLIRDIILATDLAHHLQIFSKIEKMAQQGYDNLDSENHNLLLCLLMTSADLSDQTKNWRNTRSVAELIYKEFFRQGDLEKAIGNQPAEQMDRERAVVPNLQIAFLDGIVSPLYRVLSLLHPQTDCINHTIERTRENWSKISQKVASHEIKDQTE 866 HSP 2 Score: 73.1738 bits (178), Expect = 7.751e-13 Identity = 42/84 (50.00%), Postives = 44/84 (52.38%), Query Frame = 2
Query: 2771 IRDQTENKSHNHCD*Y*KFISISNNRFSLNFHLGTSRFFVLSFALLIIYKFVAVFDFSRDFKRVFYAVGAIGSCSHRVSTNSPI 3022
I+DQTENKSHNH LI + VFDFSRDF RVF AVGAIGSCSHRVSTNSPI
Sbjct: 861 IKDQTENKSHNH--------------------------------FLIFILELRVFDFSRDFNRVFCAVGAIGSCSHRVSTNSPI 912
BLAST of Phosphodiesterase vs. Planmine SMEST
Match: SMESG000051078.1 (SMESG000051078.1) HSP 1 Score: 788.489 bits (2035), Expect = 0.000e+0 Identity = 440/889 (49.49%), Postives = 588/889 (66.14%), Query Frame = 1
Query: 181 LLGV--VISYDEFLSKSKYAAKILFPLATAVQMHQVS--EIKHPKIRAMCTIRRTSFLYVSDL----EDLSEIISSGELDILKSNSYDILVIVSVSSSQPKESLILTFF--QKFNENSENRSKRLDFLEKQMSLTLSRLMRIHPNKIISNQINQ----------------ILELCGSLFDQDAGKLQKKVLSYLIQNTSAETGFLLLVCMDTVELLCQVIGQVIQEDPINFDAEE-----NGIFDKVLKSKTGINLGCLT--EAQLREISEIMNASKQETKIQNALCVPVRHQGTNDVIAIVCLINKSGPAQ-FTNYDEQVINECFKYTTSVLFTTIAYQNERRLKLQTEKMLVVAKNIFSRMDNLNELLLMIMQEARNLTQAERCSVFLVDEDSNELVAKVFDGLPTSSDKNERLRLQDGTEIQQPVEIRFPKAQGIAGHVATTGEMLNIKKAYDHPLFYRGVDDETGFKTKNILCFPIQDDCGKTVGVAQLCNKIKGHFFTKMDEEIAKAFSIYCCISITHSLMYKKVEDAQHRSRLANELMMYHMQIPEDDIAWLSTFSIPPVSIFLSDFESFNSIPRNVKDRDTLMACISMFDGIGLISRWRINRRTLTKFIFMVKRNYRDPPYHNWMHAFSVAHFIFICIKNLPLDKQLTELELFALFVASLCHDIDHRGTNNSFQVQSNSILAALYSSEGSVLERHHFSQTVCILNTEGCNVFESLPQKEYXXXXXXXXXXXXXXXXXHHLQIFSKIEKMAQQGYDNLDSENHNLLLCLLMTSADLSDQTKNWRNTRSVAELIYKEFFRQGDLEKAIGNQPAEQMDRERAVVPNLQIAFLDGIVSPLYRVLSLLHPQ-TDCINHTIERTRENWSKISQKVASHEIKGNSEEIF 2742
LLG+ ++SY+E K +FP + +V++ ++ E IR+ + + S L +D + S D NS + +IV + SS+ KE F Q+FN+N + K L E Q+ + RL R+ +K + Q + IL LC L D+D G LQ K++ +L Q E+ F+L + + +EL+CQ Q++ I FD E+ + IF++++K K L + + +L E+ + N K + LCVP+ +Q V A+VC+INK G Q FT D + F+YT +VL +++A+Q ERRLK+QTE ML VA NIF ++ +L LL IM EA+ LT AERCSVFLVD D+ ELV+KVFDGLPT S+++ Q PVEIR P QG+AG VATTGEMLNI AY HPLFYRGVD+ETG+KT+NILCFPI+D+ K VGVAQLCNKI G FT DE+IAKAFS+YCCISI HSLMYKKV+DAQHR++LANELM+YHMQ+ ED + WL++ P + DF SF IPR++K+ D+ +A + MF+ +G IS+WR++R TL++FI M+KR YRDPPYHNW HAFSVAHFI++CI NLPL QL +EL ALFVASLCHDIDHRGTNNSFQV S S+LAALYSSEGSVLERHHFSQT+C+LN+EGCN+FE+ +++Y LDLIRDIILATDLAHHL+I S KM YD+ + +H LL+ LLMTSADLSDQ+KNW+NTR+VA+LIY+EFF QGD+EK+IG +PAEQMDRERA VP+LQ++FLDGI P +++ + L+P + I R+ W K+++ + + +I N ++F
Sbjct: 18 LLGLSNIVSYEEIPDAVKTTINRVFPNSNSVRLEWINTRENSTKSIRSNGWMNENKIIPQSSLIINRKDRLQEQYSDYFD--SENSDNFGIIVPLISSEMKEFQAFLSFSCQEFNQNEK---KLLQTFENQVKVMFQRLERLKNSKDSNLQQSNLQDPKLDSSDFYIDSTILSLCADLHDRDPGILQVKIIRFLKQRIHMESAFILTISNNNLELVCQA-----QDEQI-FDPEKRFRVTDSIFERIMKEKICAQLSDVNMFQDKLNELELLTN-----IKWNSFLCVPIINQSDGCVSALVCMINKIGSNQSFTAEDISITQHLFQYTAAVLTSSVAFQMERRLKIQTETMLQVAMNIFRKLGDLTGLLKEIMTEAKKLTNAERCSVFLVDNDTKELVSKVFDGLPTISEQS-----------QHPVEIRIPVTQGVAGRVATTGEMLNIVDAYSHPLFYRGVDEETGYKTRNILCFPIKDENEKVVGVAQLCNKINGPCFTNYDEDIAKAFSVYCCISIMHSLMYKKVQDAQHRNKLANELMIYHMQVNEDTVKWLTSCGYPDLMDIKEDFNSFECIPRDIKEHDSALAVLGMFNTLGFISKWRLSRPTLSRFILMIKRGYRDPPYHNWTHAFSVAHFIYLCITNLPLHGQLLPIELLALFVASLCHDIDHRGTNNSFQVTSKSVLAALYSSEGSVLERHHFSQTICVLNSEGCNIFENFSRQDYHHVLDLIRDIILATDLAHHLRIISDQRKMIDTFYDSNSNHHHVLLMDLLMTSADLSDQSKNWKNTRAVAQLIYEEFFSQGDMEKSIGQKPAEQMDRERACVPSLQMSFLDGIALPCFQLFADLYPLFGQKMIENITNNRKKWEKLNEDIKNGKISANIFQLF 879
BLAST of Phosphodiesterase vs. Planmine SMEST
Match: SMESG000051078.1 (SMESG000051078.1) HSP 1 Score: 787.719 bits (2033), Expect = 0.000e+0 Identity = 441/889 (49.61%), Postives = 590/889 (66.37%), Query Frame = 1
Query: 181 LLGV--VISYDEFLSKSKYAAKILFPLATAVQMHQVS--EIKHPKIRAMCTIRRTSFLYVSDL----EDLSEIISSGELDILKSNSYDILVIVSVSSSQPKE-SLILTF-FQKFNENSENRSKRLDFLEKQMSLTLSRLMRIHPNKIISNQINQ----------------ILELCGSLFDQDAGKLQKKVLSYLIQNTSAETGFLLLVCMDTVELLCQVIGQVIQEDPINFDAEE-----NGIFDKVLKSKTGINLGCLT--EAQLREISEIMNASKQETKIQNALCVPVRHQGTNDVIAIVCLINKSGPAQ-FTNYDEQVINECFKYTTSVLFTTIAYQNERRLKLQTEKMLVVAKNIFSRMDNLNELLLMIMQEARNLTQAERCSVFLVDEDSNELVAKVFDGLPTSSDKNERLRLQDGTEIQQPVEIRFPKAQGIAGHVATTGEMLNIKKAYDHPLFYRGVDDETGFKTKNILCFPIQDDCGKTVGVAQLCNKIKGHFFTKMDEEIAKAFSIYCCISITHSLMYKKVEDAQHRSRLANELMMYHMQIPEDDIAWLSTFSIPPVSIFLSDFESFNSIPRNVKDRDTLMACISMFDGIGLISRWRINRRTLTKFIFMVKRNYRDPPYHNWMHAFSVAHFIFICIKNLPLDKQLTELELFALFVASLCHDIDHRGTNNSFQVQSNSILAALYSSEGSVLERHHFSQTVCILNTEGCNVFESLPQKEYXXXXXXXXXXXXXXXXXHHLQIFSKIEKMAQQGYDNLDSENHNLLLCLLMTSADLSDQTKNWRNTRSVAELIYKEFFRQGDLEKAIGNQPAEQMDRERAVVPNLQIAFLDGIVSPLYRVLSLLHPQ-TDCINHTIERTRENWSKISQKVASHEIKGNSEEIF 2742
LLG+ ++SY+E K +FP + +V++ ++ E IR+ + + S L +D + S D NS + +IV + SS+ KE L+F Q+FN+N + K L E Q+ + RL R+ +K + Q + IL LC L D+D G LQ K++ +L Q E+ F+L + + +EL+CQ Q++ I FD E+ + IF++++K K L + + +L E+ + N K + LCVP+ +Q V A+VC+INK G Q FT D + F+YT +VL +++A+Q ERRLK+QTE ML VA NIF ++ +L LL IM EA+ LT AERCSVFLVD D+ ELV+KVFDGLPT S+++ Q PVEIR P QG+AG VATTGEMLNI AY HPLFYRGVD+ETG+KT+NILCFPI+D+ K VGVAQLCNKI G FT DE+IAKAFS+YCCISI HSLMYKKV+DAQHR++LANELM+YHMQ+ ED + WL++ P + DF SF IPR++K+ D+ +A + MF+ +G IS+WR++R TL++FI M+KR YRDPPYHNW HAFSVAHFI++CI NLPL QL +EL ALFVASLCHDIDHRGTNNSFQV S S+LAALYSSEGSVLERHHFSQT+C+LN+EGCN+FE+ +++Y LDLIRDIILATDLAHHL+I S KM YD+ + +H LL+ LLMTSADLSDQ+KNW+NTR+VA+LIY+EFF QGD+EK+IG +PAEQMDRERA VP+LQ++FLDGI P +++ + L+P + I R+ W K+++ + + +I N ++F
Sbjct: 26 LLGLSNIVSYEEIPDAVKTTINRVFPNSNSVRLEWINTRENSTKSIRSNGWMNENKIIPQSSLIINRKDRLQEQYSDYFD--SENSDNFGIIVPLISSEMKEFQAFLSFSCQEFNQNEK---KLLQTFENQVKVMFQRLERLKNSKDSNLQQSNLQDPKLDSSDFYIDSTILSLCADLHDRDPGILQVKIIRFLKQRIHMESAFILTISNNNLELVCQA-----QDEQI-FDPEKRFRVTDSIFERIMKEKICAQLSDVNMFQDKLNELELLTN-----IKWNSFLCVPIINQSDGCVSALVCMINKIGSNQSFTAEDISITQHLFQYTAAVLTSSVAFQMERRLKIQTETMLQVAMNIFRKLGDLTGLLKEIMTEAKKLTNAERCSVFLVDNDTKELVSKVFDGLPTISEQS-----------QHPVEIRIPVTQGVAGRVATTGEMLNIVDAYSHPLFYRGVDEETGYKTRNILCFPIKDENEKVVGVAQLCNKINGPCFTNYDEDIAKAFSVYCCISIMHSLMYKKVQDAQHRNKLANELMIYHMQVNEDTVKWLTSCGYPDLMDIKEDFNSFECIPRDIKEHDSALAVLGMFNTLGFISKWRLSRPTLSRFILMIKRGYRDPPYHNWTHAFSVAHFIYLCITNLPLHGQLLPIELLALFVASLCHDIDHRGTNNSFQVTSKSVLAALYSSEGSVLERHHFSQTICVLNSEGCNIFENFSRQDYHHVLDLIRDIILATDLAHHLRIISDQRKMIDTFYDSNSNHHHVLLMDLLMTSADLSDQSKNWKNTRAVAQLIYEEFFSQGDMEKSIGQKPAEQMDRERACVPSLQMSFLDGIALPCFQLFADLYPLFGQKMIENITNNRKKWEKLNEDIKNGKISANIFQLF 887
BLAST of Phosphodiesterase vs. Planmine SMEST
Match: SMESG000075722.1 (SMESG000075722.1) HSP 1 Score: 750.74 bits (1937), Expect = 0.000e+0 Identity = 402/778 (51.67%), Postives = 535/778 (68.77%), Query Frame = 1
Query: 472 LTFFQKFNENSENRSKRLDFLEKQMSLTLSRLMRIHPNKI--------ISNQI-NQILELCGSLFDQDAGKLQKKVLSYLIQNTSAETGFLLLVCMDTVELLCQVIGQVIQEDPINFDAEENGIFDKVLKSKTGINLGCLTEAQLREISEIMN-----ASKQETKIQNALCVPVRHQGTNDVIAIVCLINKSGPAQFTNYDEQVINECFKYTTSVLFTTIAYQNERRLKLQTEKMLVVAKNIFSRMDNLNELLLMIMQEARNLTQAERCSVFLVDEDSNELVAKVFDGLPTSSDKNER--LRLQDGTEIQQPVEIRFPKAQGIAGHVATTGEMLNIKKAYDHPLFYRGVDDETGFKTKNILCFPIQDDCGKTVGVAQLCNKIKGHFFTKMDEEIAKAFSIYCCISITHSLMYKKVEDAQHRSRLANELMMYHMQIPEDDIAWLSTFSIPPVSIFLSDFESFNSIPRNVKDRDTLMACISMFDGIGLISRWRINRRTLTKFIFMVKRNYRDPPYHNWMHAFSVAHFIFICIKNLPLDKQLTELELFALFVASLCHDIDHRGTNNSFQVQSNSILAALYSSEGSVLERHHFSQTVCILNTEGCNVFESLPQKEYXXXXXXXXXXXXXXXXXHHLQIFSKIEKMAQQGYDNLDSENHNLLLCLLMTSADLSDQTKNWRNTRSVAELIYKEFFRQGDLEKAIGNQPAEQMDRERAVVPNLQIAFLDGIVSPLYRVLSLLHPQT-DCINHTIERTRENWSKISQKVASHEIKGNSEEIFRNKL 2754
LTF+ N+ +K LD LEKQ+ + RL ++ + + ISN+ N IL LCG LFD+D LQ K++++L +TGF+L+V + E CQVI I + + N I + ++K C+ + + EI + S K + L +P+ N ++AIV L++K F + D ++I F++T VL +++AY E++ K+QTE ML VA NIF ++DNL LL IM EA+ LT AERCSVFL++E++NELV+KVFDGLPT S+ + +G E +QP EIR +QGIAG VATTGE+LNI AY HPLFYRGVD+ TG++T+NILCFPI+D+ K VGVAQLCNK+ G FT DE++AKAFS+YCCISI HSLMYK V++AQHR++LANELM YHMQI E++ WLST IP VS+FL DF SF+SIPR + + ++++A +SMF + ISRWRI R L +FI MVKR YRDPPYHNW HA SVAHF ++C KNL L QL ELE+F+ FVA LCHDIDHRGTNNSFQV SNS+LAALYSSEGSVLERHHF+QT+CILN+EG N+FE+L ++EY +ALDLIRDIILATDLAHH +I ++ +M + GYD + ++ LLL LLMT ADLSDQ K+W N R+VA LIY+EFF QGDLEKAIG +PAEQMDRERA +P+LQI+FLDG+ P ++ + L+ Q + + ++ R+ W K++ + +I N ++F+ +
Sbjct: 130 LTFY--CNQWDSKSTKTLDHLEKQIKIMFQRLTVMNGSLMSPSISSAEISNETRNAILTLCGELFDRDPCVLQMKIINFLKGMIHVKTGFILIVSTEISEFGCQVIDSTIVNPELRCEIR-NSIIESIVKE------NCVKKVKSSEIQNKLGDLKVLQSLTGFKWDSLLLIPILSSLNNSLVAIVGLVDKINSESFNSKDIELIQLVFRFTNPVLISSLAYYVEKKTKVQTEAMLQVAMNIFRKLDNLTMLLKEIMTEAKKLTNAERCSVFLLEEETNELVSKVFDGLPTVSENSPTSVFITPEGEEYEQPKEIRISTSQGIAGKVATTGEILNILDAYSHPLFYRGVDESTGYRTRNILCFPIKDEKDKIVGVAQLCNKVNGPHFTSSDEDLAKAFSVYCCISIVHSLMYKNVQEAQHRNKLANELMTYHMQISEENFLWLSTCPIPEVSVFLPDFNSFDSIPRQMNEHNSVLATLSMFHTLKFISRWRIPRSVLARFILMVKRGYRDPPYHNWTHALSVAHFAYLCGKNLDLMNQLNELEIFSFFVAGLCHDIDHRGTNNSFQVTSNSVLAALYSSEGSVLERHHFNQTICILNSEGSNLFENLNRQEYQKALDLIRDIILATDLAHHFRIINQQREMIESGYDKSNPDHRKLLLFLLMTCADLSDQIKSWENARNVARLIYEEFFTQGDLEKAIGQKPAEQMDRERACIPSLQISFLDGVAIPCFQNFAKLYRQPGESMLKIMQENRKKWEKLNNDIRDGKITANIFQLFQKDM 898 The following BLAST results are available for this feature:
BLAST of Phosphodiesterase vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Phosphodiesterase vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Phosphodiesterase vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Phosphodiesterase vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Phosphodiesterase vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Phosphodiesterase vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Phosphodiesterase vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Phosphodiesterase vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Phosphodiesterase vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Phosphodiesterase vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of Phosphodiesterase vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of Phosphodiesterase vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Phosphodiesterase vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Phosphodiesterase vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30008671 ID=SMED30008671|Name=Phosphodiesterase|organism=Schmidtea mediterranea sexual|type=transcript|length=3096bpback to top protein sequence of SMED30008671-orf-1 >SMED30008671-orf-1 ID=SMED30008671-orf-1|Name=SMED30008671-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=891bp MSLKKSLKNNSNKDDDFSSKAQEVSSLLGVVISYDEFLSKSKYAAKILFPback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
|
