Beta-hexosaminidase

Overview
NameBeta-hexosaminidase
Smed IDSMED30008650
Length (bp)260
Neoblast Clusters

Zeng et. al., 2018



 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30008650

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 6

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
head regionSMED30008650SMESG000008181.1 SmedASXL_016059SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016		whole organism asexual adult RNA-sequencing evidence
pharynxSMED30008650SMESG000008181.1 dd_Smed_v4_12408_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
nervous systemSMED30008650SMESG000008181.1 dd_Smed_v4_12408_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30008650SMESG000008181.1 dd_Smed_v4_12408_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cilated neuronSMED30008650SMESG000008181.1 dd_Smed_v4_12408_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
head regionSMED30008650SMESG000008181.1 dd_Smed_v6_12408_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017		whole organism asexual adult RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Beta-hexosaminidase vs. Ensembl Human
Match: HEXA (hexosaminidase subunit alpha [Source:HGNC Symbol;Acc:HGNC:4878])

HSP 1 Score: 46.595 bits (109), Expect = 6.304e-7
Identity = 24/63 (38.10%), Postives = 36/63 (57.14%), Query Frame = 3 
Query:    3 LFPDTHVHIGLDEVGKGCWATDPRIKDFMKKNQI-ENVELLLVLFIHKQRKFTQGKVSFYGRG 188
            +FPD ++H+G DEV   CW ++P I+DFM+K    E+ + L   +I          VS YG+G
Sbjct:  311 VFPDFYLHLGGDEVDFTCWKSNPEIQDFMRKKGFGEDFKQLESFYIQTLLDI----VSSYGKG 369
[Close]
BLAST of Beta-hexosaminidase vs. Ensembl Human
Match: HEXA (hexosaminidase subunit alpha [Source:HGNC Symbol;Acc:HGNC:4878])

HSP 1 Score: 46.595 bits (109), Expect = 6.574e-7
Identity = 24/63 (38.10%), Postives = 36/63 (57.14%), Query Frame = 3 
Query:    3 LFPDTHVHIGLDEVGKGCWATDPRIKDFMKKNQI-ENVELLLVLFIHKQRKFTQGKVSFYGRG 188
            +FPD ++H+G DEV   CW ++P I+DFM+K    E+ + L   +I          VS YG+G
Sbjct:  311 VFPDFYLHLGGDEVDFTCWKSNPEIQDFMRKKGFGEDFKQLESFYIQTLLDI----VSSYGKG 369
[Close]
BLAST of Beta-hexosaminidase vs. Ensembl Human
Match: HEXA (hexosaminidase subunit alpha [Source:HGNC Symbol;Acc:HGNC:4878])

HSP 1 Score: 46.595 bits (109), Expect = 6.846e-7
Identity = 24/63 (38.10%), Postives = 36/63 (57.14%), Query Frame = 3 
Query:    3 LFPDTHVHIGLDEVGKGCWATDPRIKDFMKKNQI-ENVELLLVLFIHKQRKFTQGKVSFYGRG 188
            +FPD ++H+G DEV   CW ++P I+DFM+K    E+ + L   +I          VS YG+G
Sbjct:  322 VFPDFYLHLGGDEVDFTCWKSNPEIQDFMRKKGFGEDFKQLESFYIQTLLDI----VSSYGKG 380
[Close]
BLAST of Beta-hexosaminidase vs. Ensembl Human
Match: HEXA (hexosaminidase subunit alpha [Source:HGNC Symbol;Acc:HGNC:4878])

HSP 1 Score: 45.4394 bits (106), Expect = 1.626e-6
Identity = 16/31 (51.61%), Postives = 24/31 (77.42%), Query Frame = 3 
Query:    3 LFPDTHVHIGLDEVGKGCWATDPRIKDFMKK 95
            +FPD ++H+G DEV   CW ++P I+DFM+K
Sbjct:  269 VFPDFYLHLGGDEVDFTCWKSNPEIQDFMRK 299
[Close]
BLAST of Beta-hexosaminidase vs. Ensembl Human
Match: HEXA (hexosaminidase subunit alpha [Source:HGNC Symbol;Acc:HGNC:4878])

HSP 1 Score: 45.4394 bits (106), Expect = 1.662e-6
Identity = 16/31 (51.61%), Postives = 24/31 (77.42%), Query Frame = 3 
Query:    3 LFPDTHVHIGLDEVGKGCWATDPRIKDFMKK 95
            +FPD ++H+G DEV   CW ++P I+DFM+K
Sbjct:  311 VFPDFYLHLGGDEVDFTCWKSNPEIQDFMRK 341
[Close]
BLAST of Beta-hexosaminidase vs. Ensembl Zebrafish
Match: hexa (hexosaminidase A (alpha polypeptide) [Source:ZFIN;Acc:ZDB-GENE-050417-283])

HSP 1 Score: 43.8986 bits (102), Expect = 3.667e-6
Identity = 15/31 (48.39%), Postives = 23/31 (74.19%), Query Frame = 3 
Query:    3 LFPDTHVHIGLDEVGKGCWATDPRIKDFMKK 95
            +FPD++VH+G DEV   CW ++P +  FM+K
Sbjct:  316 VFPDSYVHLGGDEVSFACWQSNPSVGKFMEK 346
[Close]
BLAST of Beta-hexosaminidase vs. Ensembl Zebrafish
Match: hexa (hexosaminidase A (alpha polypeptide) [Source:ZFIN;Acc:ZDB-GENE-050417-283])

HSP 1 Score: 43.5134 bits (101), Expect = 5.113e-6
Identity = 15/31 (48.39%), Postives = 23/31 (74.19%), Query Frame = 3 
Query:    3 LFPDTHVHIGLDEVGKGCWATDPRIKDFMKK 95
            +FPD++VH+G DEV   CW ++P +  FM+K
Sbjct:  316 VFPDSYVHLGGDEVSFACWYSNPSVGKFMEK 346
[Close]
BLAST of Beta-hexosaminidase vs. Ensembl Mouse
Match: Hexa (hexosaminidase A [Source:MGI Symbol;Acc:MGI:96073])

HSP 1 Score: 44.669 bits (104), Expect = 2.522e-6
Identity = 18/46 (39.13%), Postives = 28/46 (60.87%), Query Frame = 3 
Query:    3 LFPDTHVHIGLDEVGKGCWATDPRIKDFMKKNQIENVELLLVLFIH 140
            +FPD ++H+G DEV   CW ++P I+ FMKK    + + L   +I 
Sbjct:  311 VFPDFYLHLGGDEVDFTCWKSNPNIQAFMKKKGFTDFKQLESFYIQ 356
[Close]
BLAST of Beta-hexosaminidase vs. Ensembl Mouse
Match: Hexb (hexosaminidase B [Source:MGI Symbol;Acc:MGI:96074])

HSP 1 Score: 43.8986 bits (102), Expect = 3.882e-6
Identity = 16/31 (51.61%), Postives = 23/31 (74.19%), Query Frame = 3 
Query:    3 LFPDTHVHIGLDEVGKGCWATDPRIKDFMKK 95
            +FPD  +H+G DEV   CWA++P I+ FMK+
Sbjct:  322 VFPDQFIHLGGDEVEFQCWASNPNIQGFMKR 352
[Close]
BLAST of Beta-hexosaminidase vs. UniProt/SwissProt
Match: sp|P06865|HEXA_HUMAN (Beta-hexosaminidase subunit alpha OS=Homo sapiens OX=9606 GN=HEXA PE=1 SV=2)

HSP 1 Score: 46.595 bits (109), Expect = 3.157e-6
Identity = 24/63 (38.10%), Postives = 36/63 (57.14%), Query Frame = 3 
Query:    3 LFPDTHVHIGLDEVGKGCWATDPRIKDFMKKNQI-ENVELLLVLFIHKQRKFTQGKVSFYGRG 188
            +FPD ++H+G DEV   CW ++P I+DFM+K    E+ + L   +I          VS YG+G
Sbjct:  311 VFPDFYLHLGGDEVDFTCWKSNPEIQDFMRKKGFGEDFKQLESFYIQTLLDI----VSSYGKG 369
[Close]
BLAST of Beta-hexosaminidase vs. UniProt/SwissProt
Match: sp|Q6AXR4|HEXB_RAT (Beta-hexosaminidase subunit beta OS=Rattus norvegicus OX=10116 GN=Hexb PE=2 SV=1)

HSP 1 Score: 46.595 bits (109), Expect = 3.485e-6
Identity = 18/36 (50.00%), Postives = 25/36 (69.44%), Query Frame = 3 
Query:    3 LFPDTHVHIGLDEVGKGCWATDPRIKDFMKKNQIEN 110
            +FPD  +H+G DEV   CWA++P I++FMKK    N
Sbjct:  321 VFPDQFIHLGGDEVEFECWASNPNIQNFMKKKGFGN 356
[Close]
BLAST of Beta-hexosaminidase vs. TrEMBL
Match: A0A2T0SM07 (Hexosaminidase OS=Spirosoma oryzae OX=1469603 GN=CLV58_11756 PE=4 SV=1)

HSP 1 Score: 59.6918 bits (143), Expect = 2.415e-8
Identity = 25/55 (45.45%), Postives = 34/55 (61.82%), Query Frame = 3 
Query:    3 LFPDTHVHIGLDEVGKGCWATDPRIKDFMKKNQIENVELLLVLFIHKQRKFTQGK 167
            LFP  +VHIG DEV K  W+  P  ++ MK+  I+NVE L   F+H+  +F Q K
Sbjct:  333 LFPSPYVHIGADEVEKSTWSQTPACQELMKREGIKNVEELQSYFVHRMERFVQSK 387
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BLAST of Beta-hexosaminidase vs. TrEMBL
Match: A0A1Q3WDA9 (Beta-hexosaminidase OS=Spirosoma sp. 48-14 OX=1895854 GN=BGO59_15525 PE=4 SV=1)

HSP 1 Score: 58.151 bits (139), Expect = 7.490e-8
Identity = 26/55 (47.27%), Postives = 32/55 (58.18%), Query Frame = 3 
Query:    3 LFPDTHVHIGLDEVGKGCWATDPRIKDFMKKNQIENVELLLVLFIHKQRKFTQGK 167
            LFP  +VHIG DEV K  WA     ++ MK+  I NVE L   F+H+  KF Q K
Sbjct:  332 LFPSEYVHIGADEVEKSTWAQSQACQELMKREGIRNVEELQSYFVHRMEKFVQSK 386
[Close]
BLAST of Beta-hexosaminidase vs. TrEMBL
Match: A0A514ZT12 (Family 20 glycosylhydrolase OS=Spirosoma sp. KCTC 42546 OX=2520506 GN=EXU85_03500 PE=4 SV=1)

HSP 1 Score: 58.151 bits (139), Expect = 8.339e-8
Identity = 26/55 (47.27%), Postives = 33/55 (60.00%), Query Frame = 3 
Query:    3 LFPDTHVHIGLDEVGKGCWATDPRIKDFMKKNQIENVELLLVLFIHKQRKFTQGK 167
            LFP  +VHIG DEV K  WA     ++ MK+  I+NVE L   F+H+  KF Q K
Sbjct:  332 LFPSPYVHIGADEVEKSTWAQSAGCQELMKRENIKNVEELQSYFVHRIEKFVQSK 386
[Close]
BLAST of Beta-hexosaminidase vs. TrEMBL
Match: A0A1S2VNP2 (Beta-hexosaminidase OS=Arsenicibacter rosenii OX=1750698 GN=BLX24_10575 PE=4 SV=1)

HSP 1 Score: 57.7658 bits (138), Expect = 1.085e-7
Identity = 25/55 (45.45%), Postives = 33/55 (60.00%), Query Frame = 3 
Query:    3 LFPDTHVHIGLDEVGKGCWATDPRIKDFMKKNQIENVELLLVLFIHKQRKFTQGK 167
            LFP  +VHIG DEV K  WA  P   + MK+  ++NVE L   F+H+  +F Q K
Sbjct:  332 LFPSQYVHIGADEVEKSTWAQTPACLELMKRENLKNVEELQSYFVHRIEQFVQSK 386
[Close]
BLAST of Beta-hexosaminidase vs. TrEMBL
Match: A0A2N1KRV2 (Beta-hexosaminidase OS=Siphonobacter sp. BAB-5404 OX=1864824 GN=BWI96_05085 PE=4 SV=1)

HSP 1 Score: 57.3806 bits (137), Expect = 1.371e-7
Identity = 27/55 (49.09%), Postives = 33/55 (60.00%), Query Frame = 3 
Query:    3 LFPDTHVHIGLDEVGKGCWATDPRIKDFMKKNQIENVELLLVLFIHKQRKFTQGK 167
            LFP  +VH+G DEV K  WA     K+ MKK  I+NVE L   FIH+ +KF   K
Sbjct:  320 LFPSKYVHLGADEVEKTTWANSEACKELMKKEGIKNVEELQSYFIHRMQKFFTSK 374
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BLAST of Beta-hexosaminidase vs. Ensembl Cavefish
Match: hexa (beta-hexosaminidase subunit alpha-like [Source:NCBI gene;Acc:103046771])

HSP 1 Score: 44.669 bits (104), Expect = 1.906e-6
Identity = 15/31 (48.39%), Postives = 23/31 (74.19%), Query Frame = 3 
Query:    3 LFPDTHVHIGLDEVGKGCWATDPRIKDFMKK 95
            +FPD++VH+G DEV   CW ++P ++ FM K
Sbjct:  315 VFPDSYVHLGGDEVNFACWKSNPNVRAFMTK 345
[Close]
BLAST of Beta-hexosaminidase vs. Ensembl Sea Lamprey
Match: hexa (hexosaminidase A (alpha polypeptide) [Source:ZFIN;Acc:ZDB-GENE-050417-283])

HSP 1 Score: 42.3578 bits (98), Expect = 2.152e-6
Identity = 15/30 (50.00%), Postives = 21/30 (70.00%), Query Frame = 3 
Query:    6 FPDTHVHIGLDEVGKGCWATDPRIKDFMKK 95
            FPD ++H+G DEV   CW ++P I  FM+K
Sbjct:  291 FPDHYIHLGGDEVSFSCWQSNPDITSFMEK 320
[Close]
BLAST of Beta-hexosaminidase vs. Ensembl Nematostella
Match: EDO49845 (Beta-hexosaminidase [Source:UniProtKB/TrEMBL;Acc:A7RET7])

HSP 1 Score: 45.4394 bits (106), Expect = 3.549e-7
Identity = 16/30 (53.33%), Postives = 23/30 (76.67%), Query Frame = 3 
Query:    6 FPDTHVHIGLDEVGKGCWATDPRIKDFMKK 95
            FPD ++H+G DEVG GCW ++P I  +M+K
Sbjct:  328 FPDQYIHLGGDEVGFGCWQSNPNITAWMEK 357
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BLAST of Beta-hexosaminidase vs. Ensembl Nematostella
Match: EDO32721 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SU89])

HSP 1 Score: 45.0542 bits (105), Expect = 4.141e-7
Identity = 16/30 (53.33%), Postives = 23/30 (76.67%), Query Frame = 3 
Query:    6 FPDTHVHIGLDEVGKGCWATDPRIKDFMKK 95
            FPD ++H+G DEVG GCW ++P I  +M+K
Sbjct:  571 FPDQYIHLGGDEVGFGCWQSNPNITAWMEK 600
[Close]
BLAST of Beta-hexosaminidase vs. Ensembl Medaka
Match: hexa (beta-hexosaminidase subunit alpha [Source:NCBI gene;Acc:101172329])

HSP 1 Score: 43.8986 bits (102), Expect = 2.821e-6
Identity = 14/31 (45.16%), Postives = 24/31 (77.42%), Query Frame = 3 
Query:    3 LFPDTHVHIGLDEVGKGCWATDPRIKDFMKK 95
            +FPD+++H+G DEV   CW ++P ++ FM+K
Sbjct:  321 VFPDSYIHLGGDEVDFSCWRSNPHVRAFMQK 351
[Close]
BLAST of Beta-hexosaminidase vs. Planmine SMEST
Match: SMESG000008181.1 (SMESG000008181.1)

HSP 1 Score: 168.703 bits (426), Expect = 1.080e-50
Identity = 76/76 (100.00%), Postives = 76/76 (100.00%), Query Frame = 3 
Query:    3 LFPDTHVHIGLDEVGKGCWATDPRIKDFMKKNQIENVELLLVLFIHKQRKFTQGKVSFYGRGTKTRSFHFRICDLQ 230
            LFPDTHVHIGLDEVGKGCWATDPRIKDFMKKNQIENVELLLVLFIHKQRKFTQGKVSFYGRGTKTRSFHFRICDLQ
Sbjct:  379 LFPDTHVHIGLDEVGKGCWATDPRIKDFMKKNQIENVELLLVLFIHKQRKFTQGKVSFYGRGTKTRSFHFRICDLQ 454
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BLAST of Beta-hexosaminidase vs. Planmine SMEST
Match: SMESG000008181.1 (SMESG000008181.1)

HSP 1 Score: 105.916 bits (263), Expect = 4.299e-28
Identity = 47/47 (100.00%), Postives = 47/47 (100.00%), Query Frame = 3 
Query:    3 LFPDTHVHIGLDEVGKGCWATDPRIKDFMKKNQIENVELLLVLFIHK 143
            LFPDTHVHIGLDEVGKGCWATDPRIKDFMKKNQIENVELLLVLFIHK
Sbjct:  379 LFPDTHVHIGLDEVGKGCWATDPRIKDFMKKNQIENVELLLVLFIHK 425
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BLAST of Beta-hexosaminidase vs. Planmine SMEST
Match: SMESG000008181.1 (SMESG000008181.1)

HSP 1 Score: 105.531 bits (262), Expect = 4.519e-28
Identity = 47/47 (100.00%), Postives = 47/47 (100.00%), Query Frame = 3 
Query:    3 LFPDTHVHIGLDEVGKGCWATDPRIKDFMKKNQIENVELLLVLFIHK 143
            LFPDTHVHIGLDEVGKGCWATDPRIKDFMKKNQIENVELLLVLFIHK
Sbjct:  379 LFPDTHVHIGLDEVGKGCWATDPRIKDFMKKNQIENVELLLVLFIHK 425
[Close]
BLAST of Beta-hexosaminidase vs. Planmine SMEST
Match: SMESG000037355.1 (SMESG000037355.1)

HSP 1 Score: 45.0542 bits (105), Expect = 8.080e-7
Identity = 18/36 (50.00%), Postives = 24/36 (66.67%), Query Frame = 3 
Query:    3 LFPDTHVHIGLDEVGKGCWATDPRIKDFMKKNQIEN 110
            +FPDT +H+G DEV   CW ++PRI +F  KN   N
Sbjct:  302 IFPDTLLHLGGDEVNFNCWKSNPRIVNFTVKNGFPN 337
The following BLAST results are available for this feature:
BLAST of Beta-hexosaminidase vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
HEXA6.304e-738.10hexosaminidase subunit alpha [Source:HGNC Symbol;A... [more]
HEXA6.574e-738.10hexosaminidase subunit alpha [Source:HGNC Symbol;A... [more]
HEXA6.846e-738.10hexosaminidase subunit alpha [Source:HGNC Symbol;A... [more]
HEXA1.626e-651.61hexosaminidase subunit alpha [Source:HGNC Symbol;A... [more]
HEXA1.662e-651.61hexosaminidase subunit alpha [Source:HGNC Symbol;A... [more]
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BLAST of Beta-hexosaminidase vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Beta-hexosaminidase vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Beta-hexosaminidase vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 2
Match NameE-valueIdentityDescription
hexa3.667e-648.39hexosaminidase A (alpha polypeptide) [Source:ZFIN;... [more]
hexa5.113e-648.39hexosaminidase A (alpha polypeptide) [Source:ZFIN;... [more]
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BLAST of Beta-hexosaminidase vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Beta-hexosaminidase vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 2
Match NameE-valueIdentityDescription
Hexa2.522e-639.13hexosaminidase A [Source:MGI Symbol;Acc:MGI:96073][more]
Hexb3.882e-651.61hexosaminidase B [Source:MGI Symbol;Acc:MGI:96074][more]
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BLAST of Beta-hexosaminidase vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 2
Match NameE-valueIdentityDescription
sp|P06865|HEXA_HUMAN3.157e-638.10Beta-hexosaminidase subunit alpha OS=Homo sapiens ... [more]
sp|Q6AXR4|HEXB_RAT3.485e-650.00Beta-hexosaminidase subunit beta OS=Rattus norvegi... [more]
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BLAST of Beta-hexosaminidase vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A2T0SM072.415e-845.45Hexosaminidase OS=Spirosoma oryzae OX=1469603 GN=C... [more]
A0A1Q3WDA97.490e-847.27Beta-hexosaminidase OS=Spirosoma sp. 48-14 OX=1895... [more]
A0A514ZT128.339e-847.27Family 20 glycosylhydrolase OS=Spirosoma sp. KCTC ... [more]
A0A1S2VNP21.085e-745.45Beta-hexosaminidase OS=Arsenicibacter rosenii OX=1... [more]
A0A2N1KRV21.371e-749.09Beta-hexosaminidase OS=Siphonobacter sp. BAB-5404 ... [more]
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BLAST of Beta-hexosaminidase vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 1
Match NameE-valueIdentityDescription
hexa1.906e-648.39beta-hexosaminidase subunit alpha-like [Source:NCB... [more]
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BLAST of Beta-hexosaminidase vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1
Match NameE-valueIdentityDescription
hexa2.152e-650.00hexosaminidase A (alpha polypeptide) [Source:ZFIN;... [more]
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BLAST of Beta-hexosaminidase vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Beta-hexosaminidase vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 2
Match NameE-valueIdentityDescription
EDO498453.549e-753.33Beta-hexosaminidase [Source:UniProtKB/TrEMBL;Acc:... [more]
EDO327214.141e-753.33Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Beta-hexosaminidase vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 1
Match NameE-valueIdentityDescription
hexa2.821e-645.16beta-hexosaminidase subunit alpha [Source:NCBI gen... [more]
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BLAST of Beta-hexosaminidase vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 4
Match NameE-valueIdentityDescription
SMESG000008181.11.080e-50100.00SMESG000008181.1[more]
SMESG000008181.14.299e-28100.00SMESG000008181.1[more]
SMESG000008181.14.519e-28100.00SMESG000008181.1[more]
SMESG000037355.18.080e-750.00SMESG000037355.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30008650 ID=SMED30008650|Name=Beta-hexosaminidase|organism=Schmidtea mediterranea sexual|type=transcript|length=260bp
TTCTGTTTCCTGATACTCATGTTCATATCGGTTTAGATGAAGTTGGTAAA
GGATGCTGGGCAACTGATCCGAGAATTAAAGACTTTATGAAAAAGAATCA
AATAGAAAATGTCGAATTGTTGCTAGTTTTATTTATTCACAAACAAAGAA
AATTTACACAAGGAAAGGTAAGTTTTTATGGACGTGGAACGAAGACGCGG
TCTTTCCATTTCCGCATTTGTGATCTACAGTAACGAAGATAAACGTTATG
AACTATTGTT
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: INTERPRO
TermDefinition
IPR015883Glyco_hydro_20_cat
IPR013781Glyco_hydro_catalytic_dom
IPR017853Glycoside_hydrolase_SF
Vocabulary: biological process
TermDefinition
GO:0005975carbohydrate metabolic process
GO:0008152metabolic process
Vocabulary: molecular function
TermDefinition
GO:0004553hydrolase activity, hydrolyzing O-glycosyl compounds
GO:0004563beta-N-acetylhexosaminidase activity
GO:0016787hydrolase activity
GO:0016798hydrolase activity, acting on glycosyl bonds
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR015883Glycoside hydrolase family 20, catalytic domainPFAMPF00728Glyco_hydro_20coord: 1..54
e-value: 3.1E-9
score: 36.7
NoneNo IPR availableGENE3DG3DSA:3.20.20.80coord: 1..65
e-value: 9.6E-11
score: 43.4
IPR017853Glycoside hydrolase superfamilySUPERFAMILYSSF51445(Trans)glycosidasescoord: 1..54