Adenosine deaminase

Overview
NameAdenosine deaminase
Smed IDSMED30008618
Length (bp)1169
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Adenosine deaminase (SMED30008618) t-SNE clustered cells

Violin plots show distribution of expression levels for Adenosine deaminase (SMED30008618) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Adenosine deaminase (SMED30008618) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Adenosine deaminase (SMED30008618) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30008618

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 4

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
pharynxSMED30008618SMESG000022051.1 dd_Smed_v4_3903_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
gutSMED30008618SMESG000022051.1 dd_Smed_v4_3903_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30008618SMESG000022051.1 dd_Smed_v4_3903_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30008618SMESG000022051.1 dd_Smed_v4_3903_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Adenosine deaminase vs. Ensembl Human
Match: ADA (adenosine deaminase [Source:HGNC Symbol;Acc:HGNC:186])

HSP 1 Score: 244.588 bits (623), Expect = 2.427e-77
Identity = 130/339 (38.35%), Postives = 200/339 (59.00%), Query Frame = 3 
Query:   72 IELHSHIDGSFKPKTILEVGKRRDKILPFKTEEEIKTHLRCDKYKSLRDFLEPFELILPVFKGDKEAVWQMAYDFIEQCAESKTCYVEGRLCPYILADS------------NLDSDLVIKTILDAFSVGKSSFNVESRLIICGLREQAVNMNELLDIAKHWKPHGVVGIDIAGDEQLSMESGGTHETLVKIFKEAEKSGIHRTVHAGENGSSASIREAVYEMHAERIGHGYRVLDDLQLYEDLKKKNIHFETCPSTSFMTGSVAKDPLQHAIVKFAQDKVNYSINTDDTMMTGRLLDSEMEYASALFDLSSSELNRTRLNAAKSCFLDGEEKQNLINHL 1052
            +ELH H+DGS KP+TIL  G+RR   LP  T E +   +  DK  +L DFL  F+  +P   G +EA+ ++AY+F+E  A+    YVE R  P++LA+S            +L  D V+  +      G+  F V++R I+C +R Q     +++++ K ++   VV ID+AGDE +   S       V+ ++EA KSGIHRTVHAGE GS+  ++EAV  +  ER+GHGY  L+D  LY  L+++N+HFE CP +S++TG+   D  +HA+++   D+ NYS+NTDD ++    LD++ +        +  E  R  +NAAKS FL  +EK+ L++ L
Sbjct:   12 VELHVHLDGSIKPETILYYGRRRGIALPANTAEGLLNVIGMDKPLTLPDFLAKFDYYMPAIAGCREAIKRIAYEFVEMKAKEGVVYVEVRYSPHLLANSKVEPIPWNQAEGDLTPDEVVALVGQGLQEGERDFGVKARSILCCMRHQPNWSPKVVELCKKYQQQTVVAIDLAGDETIPGSS--LLPGHVQAYQEAVKSGIHRTVHAGEVGSAEVVKEAVDILKTERLGHGYHTLEDQALYNRLRQENMHFEICPWSSYLTGAWKPD-TEHAVIRLKNDQANYSLNTDDPLIFKSTLDTDYQMTKRDMGFTEEEFKRLNINAAKSSFLPEDEKRELLDLL 347
[Close]
BLAST of Adenosine deaminase vs. Ensembl Human
Match: ADA (adenosine deaminase [Source:HGNC Symbol;Acc:HGNC:186])

HSP 1 Score: 198.749 bits (504), Expect = 5.678e-60
Identity = 114/339 (33.63%), Postives = 181/339 (53.39%), Query Frame = 3 
Query:   72 IELHSHIDGSFKPKTILEVGKRRDKILPFKTEEEIKTHLRCDKYKSLRDFLEPFELILPVFKGDKEAVWQMAYDFIEQCAESKTCYVEGRLCPYILADS------------NLDSDLVIKTILDAFSVGKSSFNVESRLIICGLREQAVNMNELLDIAKHWKPHGVVGIDIAGDEQLSMESGGTHETLVKIFKEAEKSGIHRTVHAGENGSSASIREAVYEMHAERIGHGYRVLDDLQLYEDLKKKNIHFETCPSTSFMTGSVAKDPLQHAIVKFAQDKVNYSINTDDTMMTGRLLDSEMEYASALFDLSSSELNRTRLNAAKSCFLDGEEKQNLINHL 1052
            +ELH H+DGS KP+TIL  G+RR   LP  T E +   +  DK  +L DFL  F+  +P   G +EA+ ++AY+F+E  A+    YVE R  P++LA+S            +L  D V+  +      G+  F V++R I+C +R Q     +++++ K ++   VV ID+AGDE +   S      L+    +A                     +AV  +  ER+GHGY  L+D  LY  L+++N+HFE CP +S++TG+   D  +HA+++   D+ NYS+NTDD ++    LD++ +        +  E  R  +NAAKS FL  +EK+ L++ L
Sbjct:   12 VELHVHLDGSIKPETILYYGRRRGIALPANTAEGLLNVIGMDKPLTLPDFLAKFDYYMPAIAGCREAIKRIAYEFVEMKAKEGVVYVEVRYSPHLLANSKVEPIPWNQAEGDLTPDEVVALVGQGLQEGERDFGVKARSILCCMRHQPNWSPKVVELCKKYQQQTVVAIDLAGDETIPGSS------LLPGHVQA--------------------YQAVDILKTERLGHGYHTLEDQALYNRLRQENMHFEICPWSSYLTGAWKPD-TEHAVIRLKNDQANYSLNTDDPLIFKSTLDTDYQMTKRDMGFTEEEFKRLNINAAKSSFLPEDEKRELLDLL 323
[Close]
BLAST of Adenosine deaminase vs. Ensembl Human
Match: ADA (adenosine deaminase [Source:HGNC Symbol;Acc:HGNC:186])

HSP 1 Score: 181.8 bits (460), Expect = 2.639e-54
Identity = 99/252 (39.29%), Postives = 148/252 (58.73%), Query Frame = 3 
Query:   72 IELHSHIDGSFKPKTILEVGKRRDKILPFKTEEEIKTHLRCDKYKSLRDFLEPFELILPVFKGDKEAVWQMAYDFIEQCAESKTCYVEGRLCPYILADS------------NLDSDLVIKTILDAFSVGKSSFNVESRLIICGLREQAVNMNELLDIAKHWKPHGVVGIDIAGDEQLSMESGGTHETLVKIFKEAEKSGIHRTVHAGENGSSASIREAVYEMHAERIGHGYRVLDDLQLYEDLKKKNIHFET 791
            +ELH H+DGS KP+TIL  G+RR   LP  T E +   +  DK  +L DFL  F+  +P   G +EA+ ++AY+F+E  A+    YVE R  P++LA+S            +L  D V+  +      G+  F V++R I+C +R Q     +++++ K ++   VV ID+AGDE +   S       V+ ++EA KSGIHRTVHAGE GS+  ++EAV  +  ER+GHGY  L+D  LY  L+++N+HFE 
Sbjct:   12 VELHVHLDGSIKPETILYYGRRRGIALPANTAEGLLNVIGMDKPLTLPDFLAKFDYYMPAIAGCREAIKRIAYEFVEMKAKEGVVYVEVRYSPHLLANSKVEPIPWNQAEGDLTPDEVVALVGQGLQEGERDFGVKARSILCCMRHQPNWSPKVVELCKKYQQQTVVAIDLAGDETIPGSS--LLPGHVQAYQEAVKSGIHRTVHAGEVGSAEVVKEAVDILKTERLGHGYHTLEDQALYNRLRQENMHFEA 261
[Close]
BLAST of Adenosine deaminase vs. Ensembl Human
Match: ADA (adenosine deaminase [Source:HGNC Symbol;Acc:HGNC:186])

HSP 1 Score: 55.8398 bits (133), Expect = 1.290e-9
Identity = 27/59 (45.76%), Postives = 36/59 (61.02%), Query Frame = 3 
Query:   72 IELHSHIDGSFKPKTILEVGKRRDKILPFKTEEEIKTHLRCDKYKSLRDFLEPFELILP 248
            +ELH H+DGS KP+TIL  G+RR   LP  T E +   +  DK  +L DFL  F+  +P
Sbjct:   12 VELHVHLDGSIKPETILYYGRRRGIALPANTAEGLLNVIGMDKPLTLPDFLAKFDYYMP 70
[Close]
BLAST of Adenosine deaminase vs. Ensembl Human
Match: ADAL (adenosine deaminase like [Source:HGNC Symbol;Acc:HGNC:31853])

HSP 1 Score: 52.7582 bits (125), Expect = 4.736e-7
Identity = 65/320 (20.31%), Postives = 138/320 (43.12%), Query Frame = 3 
Query:   51 FDPKFYNIELHSHIDGSFKPKTILEVGKRRDKILPFKTEEEIKTHLRCDKYKSLRDFLEPFELILPV--FKGDKEAVWQMAYDFIEQCAESKTCYVEGRLCPYILADSNLDSDLVIKTILDAFSVGKS-SFNVESR-LIICGLREQAVNMNELLDIAKHW---KPHGVVGIDIAGDEQLSMESGGTHETLVKIFKEAEKSGIHRTVHAGENGSSASIREAVYEMHAERIGHGYRVLD----DLQLYEDLKKKNIHFETCPSTSFMTGSVAKDPLQHAIVKFAQDKVNYSINTDDTMMTGRLLDSEMEYASALFDLSSSEL 977
            F  +   +ELH+H++GS    T+        K++  K + +I   +        R   E F++   +       E +  +  D I++ A+    Y+E R  P     + +     +++IL+     K  + +++ R LI    R   +   E + +A+ +       V+G+D++GD  +     G  +  ++   EA+K+G+   +H  E  +     + + ++  +RIGHG  +       L L + +++  I  E C +++  + +V      H    ++    +  I TDD  +    L  E + A+  F+L+ S++
Sbjct:   14 FYSELPKVELHAHLNGSISSHTM-------KKLIAQKPDLKIHDQMTVIDKGKKRTLEECFQMFQTIHQLTSSPEDILMVTKDVIKEFADDGVKYLELRSTPRRENATGMTKKTYVESILEGIKQSKQENLDIDVRYLIAVDRRGGPLVAKETVKLAEEFFLSTEGTVLGLDLSGDPTV-----GQAKDFLEPLLEAKKAGLKLALHLSEIPNQKKETQILLDLLPDRIGHGTFLNSGEGGSLDLVDFVRQHRIPLELCLTSNVKSQTVPSYDQHHFGFWYSIAHPSV-ICTDDKGVFATHLSQEYQLAAETFNLTQSQV 320
[Close]
BLAST of Adenosine deaminase vs. Ensembl Celegans
Match: C06G3.5 (pep chromosome:WBcel235:IV:7026472:7028121:1 gene:WBGene00015551.1 transcript:C06G3.5b.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:C06G3.5)

HSP 1 Score: 207.223 bits (526), Expect = 1.852e-63
Identity = 127/354 (35.88%), Postives = 195/354 (55.08%), Query Frame = 3 
Query:   27 IYESLNMIFDPKFYNIELHSHIDGSFKPKTILEVGKRRDKILP-FKTEEEIKTHLRCDKYKSLRDFLEPFELILPVFKGDKEAVWQMAYDFIEQCAESKTCYVEGRLCPYILADSNLDSDLVIKTIL---DAFSVGKSSFNVESRLIICGLREQAVNMNEL-LDIAKHWKPHGVVGIDIAG-----DEQLSMESGGTHETLVKIFKEAEKSGIHRTVHAGENGSSASIREAVYEMHAERIGHGYRVLDDLQLYED--LKKKNIHFETCPSTSFMTGSVAKDPLQHAIVKFAQDKVNYSINTDDTMMTGRLLDSEMEYASALFDLSSSELNRTRLNAAKSCFLDGEEKQNLINHL 1052
            ++E LN      F  +ELH H+DG+ +  T++++ +++   L   KT EE+K  L   +  +L   LE FE+ LPV +GD  A+ ++AY+  E    +   Y EGR  P++L  ++         +      F  G+  F +++R I+C +R       +L LD+A   K  GVV ID+AG     DEQ   E       +V  F+EA K GIHRTVHAGE+G    + +A+ +M+AERIGHGYRV+ D ++Y +  +  KN+H E CP +S MTG+V  D   H I ++A+D VN+S++ DD       + SE+        L   +L + +LNAA+SCFL  +EK  L+  +
Sbjct:    1 MHERLN------FPKVELHLHLDGAVRFDTLIDLSQQKGIPLAGAKTVEELKKVLVTHEPANLSKVLEAFEIFLPVIRGDLAAIERVAYELCEDQHNNGVVYFEGRYSPHLLLCNDYPEVTAAHVVAAVKKGFDRGEKQFGIKARSILCCIRGLDKKFPQLILDLATDLKQLGVVAIDVAGSAHGADEQYEPE-------VVAAFQEAHKRGIHRTVHAGESGGPKEVIKAIEDMYAERIGHGYRVMRDEEMYLEHFVNSKNVHLEACPYSSVMTGAVPLDWKNHPIARWAKDDVNFSVSRDDPTCFDNSMLSELTLVHKQIGLDVHQLWKAQLNAARSCFLPEDEKAELVKRV 341
[Close]
BLAST of Adenosine deaminase vs. Ensembl Celegans
Match: C06G3.5 (pep chromosome:WBcel235:IV:7024211:7028144:1 gene:WBGene00015551.1 transcript:C06G3.5a.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:C06G3.5)

HSP 1 Score: 207.223 bits (526), Expect = 4.989e-63
Identity = 127/354 (35.88%), Postives = 195/354 (55.08%), Query Frame = 3 
Query:   27 IYESLNMIFDPKFYNIELHSHIDGSFKPKTILEVGKRRDKILP-FKTEEEIKTHLRCDKYKSLRDFLEPFELILPVFKGDKEAVWQMAYDFIEQCAESKTCYVEGRLCPYILADSNLDSDLVIKTIL---DAFSVGKSSFNVESRLIICGLREQAVNMNEL-LDIAKHWKPHGVVGIDIAG-----DEQLSMESGGTHETLVKIFKEAEKSGIHRTVHAGENGSSASIREAVYEMHAERIGHGYRVLDDLQLYED--LKKKNIHFETCPSTSFMTGSVAKDPLQHAIVKFAQDKVNYSINTDDTMMTGRLLDSEMEYASALFDLSSSELNRTRLNAAKSCFLDGEEKQNLINHL 1052
            ++E LN      F  +ELH H+DG+ +  T++++ +++   L   KT EE+K  L   +  +L   LE FE+ LPV +GD  A+ ++AY+  E    +   Y EGR  P++L  ++         +      F  G+  F +++R I+C +R       +L LD+A   K  GVV ID+AG     DEQ   E       +V  F+EA K GIHRTVHAGE+G    + +A+ +M+AERIGHGYRV+ D ++Y +  +  KN+H E CP +S MTG+V  D   H I ++A+D VN+S++ DD       + SE+        L   +L + +LNAA+SCFL  +EK  L+  +
Sbjct:   43 MHERLN------FPKVELHLHLDGAVRFDTLIDLSQQKGIPLAGAKTVEELKKVLVTHEPANLSKVLEAFEIFLPVIRGDLAAIERVAYELCEDQHNNGVVYFEGRYSPHLLLCNDYPEVTAAHVVAAVKKGFDRGEKQFGIKARSILCCIRGLDKKFPQLILDLATDLKQLGVVAIDVAGSAHGADEQYEPE-------VVAAFQEAHKRGIHRTVHAGESGGPKEVIKAIEDMYAERIGHGYRVMRDEEMYLEHFVNSKNVHLEACPYSSVMTGAVPLDWKNHPIARWAKDDVNFSVSRDDPTCFDNSMLSELTLVHKQIGLDVHQLWKAQLNAARSCFLPEDEKAELVKRV 383
[Close]
BLAST of Adenosine deaminase vs. Ensembl Celegans
Match: C44B7.12 (Adenosine deaminase-like protein [Source:UniProtKB/Swiss-Prot;Acc:Q8IG39])

HSP 1 Score: 58.5362 bits (140), Expect = 3.064e-9
Identity = 76/312 (24.36%), Postives = 137/312 (43.91%), Query Frame = 3 
Query:   72 IELHSHIDGSFKPKT---ILEVGKRRDKILPFKTEEEIKTHLRCDKYKSLRDFLEPFELILPVFKGDKEAVWQMAYDFIEQCAESKTCYVEGRLCPYILADSNLDSDLVIKTILDAFSVGKSSF-NVESRLIICGLR----EQAVNMNELLDIAKHWKPHGVVGIDIAGDEQLSMESGGTHETLVKIFKEAEK-SGIHRTVHAGENGSSASIREAVYEMHAERIGHGYRVLDDLQLYEDLKKKNIHFETCPSTSFMTGSVAKDPLQHAIVKFAQDKVNYSINTDDT-MMTGRLLDSEMEYASALFDLSSSEL 977
            +ELH+H+ GS  P+T   I+E  + R         EEI    + +K +++    + F +I  + +   EA+       I++  E    Y+E R  P       +  +  ++  +++F   K  F  +++ LI+   R    E A ++  L+  A+  + + +VG++++GD  L          L+K+F  A +  G+  T+H  E   + +  E    +  +RIGHG  +  D        K  I  E C S++  + +       H    + +  V   I TDD  ++ G  L  E   A+  FDLS+ EL
Sbjct:   62 VELHAHLSGSLSPETIKLIMESDETR--------AEEIMKKYKLEKPENMTGVFDCFPVIHAILRK-PEAIRIAIRQTIKEFEEDNCVYLELRTSPK--ETDFMTYEDYLQVCIESFEAAKHEFPRIKTFLIVSLDRRMPFETAAHILGLIGEAQQ-RTNVIVGVELSGDPHLDGRR------LLKLFVAARRFHGLGITIHLAEVLQNMADVEDYLNLRPDRIGHGTFLHTDPYTEYLTNKYKIPLEICLSSNVYSKTTTNYRNSH-FNYWRKRGVPVFICTDDKGVIPGATLTEEYYKAAITFDLSTEEL 354
[Close]
BLAST of Adenosine deaminase vs. Ensembl Fly
Match: Ada (gene:FBgn0037661 transcript:FBtr0081971)

HSP 1 Score: 60.4622 bits (145), Expect = 7.255e-10
Identity = 70/338 (20.71%), Postives = 147/338 (43.49%), Query Frame = 3 
Query:   72 IELHSHIDGSFKPKTILEVGKRRDKILPFKTEEEIKTHLRCDKY-KSLRDFLEPFELILPVFKGDKEAVWQMAYDFIEQCAESKTCYVEGRLCPYILADSNLDSDLVIKTILDAFSVGKSSF-NVESRLIICGLREQAVNMNE-----LLDIAKHWKPHGVVGIDIAGDEQLSMESGGTHETLVKIFKEAEKSGIHRTVHAGENGSSASIREAVYEMHAERIGHG-YRVLDDLQLYEDLKKKNIHFETCPSTSFMTGSVAKDPLQHAIVKFAQDKVNYSINTDDTMMTGRLLDSEMEYASALFDLSSSELNRTRLNAAKSCFLDGEEKQNLINHLAEF 1061
            +ELH+H++GS   K++ ++G+R   +     ++ +K      ++ K +    E F  +  +    +E +       I   AE    YVE R  P   A+ N      ++ ++DA      ++  +  +L+    R + V++ E      +++A+   P+ ++GID++G+        G       I  +A   G+   +H  E  + + ++E ++     R GHG +   +D+     LK++NI  E C +++  +G+V     +H + +  +      I TDD+ +    L  E   A+  F L+  +     L A    F   +E+  + + +  +
Sbjct:   11 VELHAHLNGSLGIKSLCDLGER---LYGTSCKDFLKLCAHFSRFEKDMDACFEKFAFVHEL-TSTREGLRFATELAIRDFAEDNVQYVEMRTTPK--ANENYSRRDYLQIVIDAIKAASETYPEITVKLLPSINRAEPVDVAEETVSLAVELAR-AHPNLILGIDLSGN-----PGKGRFSDFAPILAQARDKGLKLAIHCAEIENPSEVKEMLH-FGMSRCGHGTFLTPEDIG---QLKQRNIAIECCLTSNVKSGTVPSLE-EHHLKRIMEADAPKVICTDDSGVFDTTLTKEFLIAAETFGLTREQCIDLTLEAVHHSFASEQEQIQMADRVGNY 331
[Close]
BLAST of Adenosine deaminase vs. Ensembl Zebrafish
Match: ada (adenosine deaminase [Source:NCBI gene;Acc:436919])

HSP 1 Score: 259.61 bits (662), Expect = 2.076e-83
Identity = 135/341 (39.59%), Postives = 202/341 (59.24%), Query Frame = 3 
Query:   72 IELHSHIDGSFKPKTILEVGKRRDKILPFKTEEEIKTHLRCDKYKSLRDFLEPFELILPVFKGDKEAVWQMAYDFIEQCAESKTCYVEGRLCPYILADSNLDS------------DLVIKTILDAFSVGKSSFNVESRLIICGLREQAVNMNELLDIAKHWKPHGVVGIDIAGDEQLSMESGGTHETLVKIFKEAEKSGIHRTVHAGENGSSASIREAVYEMHAERIGHGYRVLDDLQLYEDLKKKNIHFETCPSTSFMTGSVAKDPLQHAIVKFAQDKVNYSINTDDTMMTGRLLDSEMEYASALFDLSSSELNRTRLNAAKSCFLDGEEKQNLINHLAE 1058
            +ELH H+DG+ + KT+L+V KRR   LP   EEE+K     ++  +L +FL  F   + V  GD+EA+ ++AY+F+E  A+    YVE R  P+ LA+  ++             D V+  +   F  G+ +F  ++R I+C +R       E++++ K +   GVV ID+AGDE ++ ES   H+   K F+EA +S +HRTVHAGE G ++ +REAV  + AERIGHGY  L+D  LY+ L  +N+HFE CP +S +TG+   D  +H ++ F +DK NYS+NTDD  +    L+S+ E      D +  E  R  +NAAKSCFL  +EK+ L+N L E
Sbjct:   15 VELHVHLDGAIRLKTVLDVAKRRGISLPVSMEEELKELCTVNEPATLTEFLGKFSHFMHVIAGDREAIKRIAYEFVETKAKEGVIYVEARYSPHFLANKGVEPLPWDQKPGDITPDDVVDLVNQGFKEGEQAFKTKARSILCCMRHMPNWSMEVVELCKKFHKDGVVAIDLAGDESMNCESYPGHK---KAFEEAVRSNVHRTVHAGEVGPASVVREAVEVLKAERIGHGYHTLEDQNLYKQLLHQNMHFEMCPVSSRLTGACEPDFTKHPLITFKKDKANYSLNTDDPTIFNSTLNSDYEVVQKYMDFTEEEFKRLNINAAKSCFLPEKEKEKLLNQLYE 352
[Close]
BLAST of Adenosine deaminase vs. Ensembl Zebrafish
Match: adal (adenosine deaminase-like [Source:NCBI gene;Acc:619263])

HSP 1 Score: 68.9366 bits (167), Expect = 1.779e-12
Identity = 81/351 (23.08%), Postives = 151/351 (43.02%), Query Frame = 3 
Query:   48 IFDPKFYNIELHSHIDGSFKPKTILEVGKRRDKILPFKTEEEIKTHLRCDKYKSLRDFLEPFELILPVFKGDKEAVWQMAYDFIEQCAESKTCYVEGRLCPYILADSNLDSDLVIKTILDAFSVGKS-SFNVESRLIICGLRE-------QAVNMNELLDIAKHWKPHGVVGIDIAGDEQLSMESGGTHETLVKIFKEAEKSGIHRTVHAGENGSSASIREAVYEMHAERIGHGYRVLDDL----QLYEDLKKKNIHFETCPSTSFMTGSVAKDPLQHAIVKFAQDKVNYSINTDDTMMTGRLLDSEMEYASALFDLSSSELNRTRLNAAKSCFLDGEEKQNLINHLAEFN 1064
            +F  +   +ELH+H++GS   +T+ ++ KR+    P    E   T +R  + ++L +  + F++I  +   + E +  +A   I++ A     Y+E R  P  + ++ L     I+T+L+A    K    +++ R ++   R        Q V + E   ++       VVG+D++GD  +     G  + L+   ++A+  G+   +H  E  S     E +  +  +RIGHG  +  D+     L + + K+NI  E C  TS + G       +H    +   +    + TDD  +    L  E + A++ F L+   +      A    F     KQ L    AE  
Sbjct:    7 LFYRQLPKVELHAHLNGSVSFETMEKLIKRK----PHLNIEHSMTAIRRGQRRTLDECFQVFKVIHQLVDSE-EDILMVAKSVIQEFAADGVKYLELRSTPREVTETGLSKQRYIETVLEAIRQCKQEGVDIDVRFLVAVDRRHGPEVAMQTVKLAEDFLLSSDGT---VVGLDLSGDPTV-----GHGKDLLAALQKAKNFGLKLALHLSEVPSQIDETELLLNLPPDRIGHGTFLHPDVGGSDSLVDKVCKQNIPIEIC-LTSNVKGQTVPSYDKHHFKYWYNRRHPCVLCTDDKGVFCTDLSQEYQLAASTFGLTKEAVWSLSQQAIGYTFAPEPIKQRLEKTWAELK 343
[Close]
BLAST of Adenosine deaminase vs. Ensembl Zebrafish
Match: adal (adenosine deaminase-like [Source:NCBI gene;Acc:619263])

HSP 1 Score: 68.9366 bits (167), Expect = 1.779e-12
Identity = 81/351 (23.08%), Postives = 151/351 (43.02%), Query Frame = 3 
Query:   48 IFDPKFYNIELHSHIDGSFKPKTILEVGKRRDKILPFKTEEEIKTHLRCDKYKSLRDFLEPFELILPVFKGDKEAVWQMAYDFIEQCAESKTCYVEGRLCPYILADSNLDSDLVIKTILDAFSVGKS-SFNVESRLIICGLRE-------QAVNMNELLDIAKHWKPHGVVGIDIAGDEQLSMESGGTHETLVKIFKEAEKSGIHRTVHAGENGSSASIREAVYEMHAERIGHGYRVLDDL----QLYEDLKKKNIHFETCPSTSFMTGSVAKDPLQHAIVKFAQDKVNYSINTDDTMMTGRLLDSEMEYASALFDLSSSELNRTRLNAAKSCFLDGEEKQNLINHLAEFN 1064
            +F  +   +ELH+H++GS   +T+ ++ KR+    P    E   T +R  + ++L +  + F++I  +   + E +  +A   I++ A     Y+E R  P  + ++ L     I+T+L+A    K    +++ R ++   R        Q V + E   ++       VVG+D++GD  +     G  + L+   ++A+  G+   +H  E  S     E +  +  +RIGHG  +  D+     L + + K+NI  E C  TS + G       +H    +   +    + TDD  +    L  E + A++ F L+   +      A    F     KQ L    AE  
Sbjct:    7 LFYRQLPKVELHAHLNGSVSFETMEKLIKRK----PHLNIEHSMTAIRRGQRRTLDECFQVFKVIHQLVDSE-EDILMVAKSVIQEFAADGVKYLELRSTPREVTETGLSKQRYIETVLEAIRQCKQEGVDIDVRFLVAVDRRHGPEVAMQTVKLAEDFLLSSDGT---VVGLDLSGDPTV-----GHGKDLLAALQKAKNFGLKLALHLSEVPSQIDETELLLNLPPDRIGHGTFLHPDVGGSDSLVDKVCKQNIPIEIC-LTSNVKGQTVPSYDKHHFKYWYNRRHPCVLCTDDKGVFCTDLSQEYQLAASTFGLTKEAVWSLSQQAIGYTFAPEPIKQRLEKTWAELK 343
[Close]
BLAST of Adenosine deaminase vs. Ensembl Xenopus
Match: ada (adenosine deaminase [Source:NCBI gene;Acc:496434])

HSP 1 Score: 239.195 bits (609), Expect = 2.709e-75
Identity = 131/342 (38.30%), Postives = 194/342 (56.73%), Query Frame = 3 
Query:   72 IELHSHIDGSFKPKTILEVGKRRDKILPFKTEEEIKTHLRCDKYKSLRDFLEPFELILPVFKGDKEAVWQMAYDFIEQCAESKTCYVEGRLCPYILADSNLDS------------DLVIKTILDAFSVGKSSFNVESRLIICGLREQA-VNMNELLDIAKHWKPHGVVGIDIAGDEQLSMESGGTHETLVKIFKEAEKSGIHRTVHAGENGSSASIREAVYEMHAERIGHGYRVLDDLQLYEDLKKKNIHFETCPSTSFMTGSVAKDPLQHAIVKFAQDKVNYSINTDDTMMTGRLLDSEMEYASALFDLSSSELNRTRLNAAKSCFLDGEEKQNLINHLAE 1058
            +ELH H+DGS KP+TI+   K+R   LP  T E +  H+   +  SL +FL  F   +P   GD+EA+ ++AY+F+E  A+    YVE R  P+ LA+S ++             D V+  +      G+ +FN+++R I+C +R     N+ E  +I  ++     V   +AGD Q   ES   H      ++EA K GIHRTVHAGE G S+ ++EAV  + AERIGHGY + +D  LY++L +KN+HFE CP +S++TG+   D  +H   +F +DK NYS+NTDD ++ G  LD +   A+     +  E  R  +NAAKS FL   EK+ L+  L E
Sbjct:   11 VELHVHLDGSIKPETIIHFAKKRQIKLPADTVEGLLEHVSYKEPLSLTEFLSKFNHYMPAIAGDREAIKRIAYEFVEMKAKEGVIYVEVRYSPHFLANSKVEPIPWGQKEGDITPDEVVDLVNQGLRKGEKAFNIKARSILCCMRHMPKWNVTECTEICSNYTRDKFVIPALAGDVQCLCESSKFHRYQ---YQEAVKCGIHRTVHAGEVGPSSVVKEAVEVLKAERIGHGYHITEDPNLYKELLEKNMHFEVCPWSSYLTGACHPDFTKHPATQFRKDKANYSLNTDDPLIFGSTLDVDYSIAAKHMGFTEEEFKRVNINAAKSSFLPESEKKELLYKLYE 349
[Close]
BLAST of Adenosine deaminase vs. Ensembl Xenopus
Match: ada (adenosine deaminase [Source:NCBI gene;Acc:496434])

HSP 1 Score: 230.335 bits (586), Expect = 6.583e-72
Identity = 128/342 (37.43%), Postives = 191/342 (55.85%), Query Frame = 3 
Query:   72 IELHSHIDGSFKPKTILEVGKRRDKILPFKTEEEIKTHLRCDKYKSLRDFLEPFELILPVFKGDKEAVWQMAYDFIEQCAESKTCYVEGRLCPYILADSNLDS------------DLVIKTILDAFSVGKSSFNVESRLIICGLREQAVN-MNELLDIAKHWKPHGVVGIDIAGDEQLSMESGGTHETLVKIFKEAEKSGIHRTVHAGENGSSASIREAVYEMHAERIGHGYRVLDDLQLYEDLKKKNIHFETCPSTSFMTGSVAKDPLQHAIVKFAQDKVNYSINTDDTMMTGRLLDSEMEYASALFDLSSSELNRTRLNAAKSCFLDGEEKQNLINHLAE 1058
            +ELH H+DGS KP+TI+   K+R   LP  T E +  H+   +  SL +FL  F   +P   GD+EA+ ++AY+F+E  A+    YVE R  P+ LA+S ++             D V+  +      G+ +FN+++R I+C +R    N   E      ++     V   +AGD Q    +G        I+++A K GIHRTVHAGE G S+ ++EAV  + AERIGHGY + +D  LY++L +KN+HFE CP +S++TG+   D  +H   +F +DK NYS+NTDD ++ G  LD +   A+     +  E  R  +NAAKS FL   EK+ L+  L E
Sbjct:   18 VELHVHLDGSIKPETIIHFAKKRQIKLPADTVEGLLEHVSYKEPLSLTEFLSKFNHYMPAIAGDREAIKRIAYEFVEMKAKEGVIYVEVRYSPHFLANSKVEPIPWGQKEGDITPDEVVDLVNQGLRKGEKAFNIKARSILCCMRHMPSNGFIEYYKFTTNYTRDKFVIPALAGDVQ----AGPI------IYRQAVKCGIHRTVHAGEVGPSSVVKEAVEVLKAERIGHGYHITEDPNLYKELLEKNMHFEVCPWSSYLTGACHPDFTKHPATQFRKDKANYSLNTDDPLIFGSTLDVDYSIAAKHMGFTEEEFKRVNINAAKSSFLPESEKKELLYKLYE 349
[Close]
BLAST of Adenosine deaminase vs. Ensembl Xenopus
Match: ada.2 (adenosine deaminase, gene 2 [Source:NCBI gene;Acc:100135194])

HSP 1 Score: 230.335 bits (586), Expect = 2.668e-71
Identity = 119/343 (34.69%), Postives = 193/343 (56.27%), Query Frame = 3 
Query:   63 FYNIELHSHIDGSFKPKTILEVGKRRDKILP-FKTEEEIKTHLRCDKYKSLRDFLEPFELILPVFKGDKEAVWQMAYDFIEQCAESKTCYVEGRLCPYILADSNLDS------------DLVIKTILDAFSVGKSSFNVESRLIICGLREQAVNMNELLDIAKHWKPHGVVGIDIAGDEQLSMESGGTHETLVKIFKEAEKSGIHRTVHAGENGSSASIREAVYEMHAERIGHGYRVLDDLQLYEDLKKKNIHFETCPSTSFMTGSVAKDPLQHAIVKFAQDKVNYSINTDDTMMTGRLLDSEMEYASALFDLSSSELNRTRLNAAKSCFLDGEEKQNLINHL 1052
            ++ ++LH H+D + KP+T+L   K++   LP  ++ E++K  + C +  SL +FL  FE+ +P   GD+EAV ++AY+F+E  A+    Y E R  P + A+  +D             D V+  +      G+  FN++ + I+C LR       +++++ K +    VVGID+AGDE L  E+   H   +K F+EA + GIHRTVHAGE G  + ++EAV  + AERIGHGY  + D  LY+ L   ++HFE CP  S++TG+   D  +H +++F +D  NYS+++D  +  G  L  +   A      +  +     +NAA+SCFL  +EK+ L+  L
Sbjct:    7 YFQVQLHIHLDAAMKPETVLYFAKKKQMHLPGIESVEDLKKKVVCTQAGSLTEFLSKFEIFMPPVAGDREAVKRIAYEFVEMEAKQGVIYCEVRYSPQLFANCKVDPIPWGQKEGDLSPDEVVDLVNQGLKEGEKDFNIKVKSILCCLRHMPNWSFDVVELCKKYHNDSVVGIDLAGDEGLKSETFPGH---LKAFQEAVRCGIHRTVHAGEAGPPSVVKEAVQMLKAERIGHGYHTIQDPTLYKRLLDMDMHFEMCPYCSYITGACDPDFTKHPLIQFKKDGANYSLSSDGPLPIGTTLQYDYALAETYMGFTEKDFMHANINAARSCFLPEDEKKELLERL 346
[Close]
BLAST of Adenosine deaminase vs. Ensembl Xenopus
Match: ada.2 (adenosine deaminase, gene 2 [Source:NCBI gene;Acc:100135194])

HSP 1 Score: 228.024 bits (580), Expect = 4.732e-71
Identity = 119/341 (34.90%), Postives = 191/341 (56.01%), Query Frame = 3 
Query:   69 NIELHSHIDGSFKPKTILEVGKRRDKILP-FKTEEEIKTHLRCDKYKSLRDFLEPFELILPVFKGDKEAVWQMAYDFIEQCAESKTCYVEGRLCPYILADSNLDS------------DLVIKTILDAFSVGKSSFNVESRLIICGLREQAVNMNELLDIAKHWKPHGVVGIDIAGDEQLSMESGGTHETLVKIFKEAEKSGIHRTVHAGENGSSASIREAVYEMHAERIGHGYRVLDDLQLYEDLKKKNIHFETCPSTSFMTGSVAKDPLQHAIVKFAQDKVNYSINTDDTMMTGRLLDSEMEYASALFDLSSSELNRTRLNAAKSCFLDGEEKQNLINHL 1052
             ++LH H+D + KP+T+L   K++   LP  ++ E++K  + C +  SL +FL  FE+ +P   GD+EAV ++AY+F+E  A+    Y E R  P + A+  +D             D V+  +      G+  FN++ + I+C LR       +++++ K +    VVGID+AGDE L  E+   H   +K F+EA + GIHRTVHAGE G  + ++EAV  + AERIGHGY  + D  LY+ L   ++HFE CP  S++TG+   D  +H +++F +D  NYS+++D  +  G  L  +   A      +  +     +NAA+SCFL  +EK+ L+  L
Sbjct:    8 TVQLHIHLDAAMKPETVLYFAKKKQMHLPGIESVEDLKKKVVCTQAGSLTEFLSKFEIFMPPVAGDREAVKRIAYEFVEMEAKQGVIYCEVRYSPQLFANCKVDPIPWGQKEGDLSPDEVVDLVNQGLKEGEKDFNIKVKSILCCLRHMPNWSFDVVELCKKYHNDSVVGIDLAGDEGLKSETFPGH---LKAFQEAVRCGIHRTVHAGEAGPPSVVKEAVQMLKAERIGHGYHTIQDPTLYKRLLDMDMHFEMCPYCSYITGACDPDFTKHPLIQFKKDGANYSLSSDGPLPIGTTLQYDYALAETYMGFTEKDFMHANINAARSCFLPEDEKKELLERL 345
[Close]
BLAST of Adenosine deaminase vs. Ensembl Xenopus
Match: ada.2 (adenosine deaminase, gene 2 [Source:NCBI gene;Acc:100135194])

HSP 1 Score: 206.068 bits (523), Expect = 5.116e-63
Identity = 108/307 (35.18%), Postives = 170/307 (55.37%), Query Frame = 3 
Query:  168 EEIKTHLRCDKYKSLRDFLEPFELILPVFKGDKEAVWQMAYDFIEQCAESKTCYVEGRLCPYILADSNLDS------------DLVIKTILDAFSVGKSSFNVESRLIICGLREQAVNMNELLDIAKHWKPHGVVGIDIAGDEQLSMESGGTHETLVKIFKEAEKSGIHRTVHAGENGSSASIREAVYEMHAERIGHGYRVLDDLQLYEDLKKKNIHFETCPSTSFMTGSVAKDPLQHAIVKFAQDKVNYSINTDDTMMTGRLLDSEMEYASALFDLSSSELNRTRLNAAKSCFLDGEEKQNLINHL 1052
            E++K  + C +  SL +FL  FE+ +P   GD+EAV ++AY+F+E  A+    Y E R  P + A+  +D             D V+  +      G+  FN++ + I+C LR       +++++ K +    VVGID+AGDE L  E+   H   +K F+EA + GIHRTVHAGE G  + ++EAV  + AERIGHGY  + D  LY+ L   ++HFE CP  S++TG+   D  +H +++F +D  NYS+++D  +  G  L  +   A      +  +     +NAA+SCFL  +EK+ L+  L
Sbjct:   10 EDLKKKVVCTQAGSLTEFLSKFEIFMPPVAGDREAVKRIAYEFVEMEAKQGVIYCEVRYSPQLFANCKVDPIPWGQKEGDLSPDEVVDLVNQGLKEGEKDFNIKVKSILCCLRHMPNWSFDVVELCKKYHNDSVVGIDLAGDEGLKSETFPGH---LKAFQEAVRCGIHRTVHAGEAGPPSVVKEAVQMLKAERIGHGYHTIQDPTLYKRLLDMDMHFEMCPYCSYITGACDPDFTKHPLIQFKKDGANYSLSSDGPLPIGTTLQYDYALAETYMGFTEKDFMHANINAARSCFLPEDEKKELLERL 313
[Close]
BLAST of Adenosine deaminase vs. Ensembl Mouse
Match: Ada (adenosine deaminase [Source:MGI Symbol;Acc:MGI:87916])

HSP 1 Score: 240.35 bits (612), Expect = 4.688e-76
Identity = 131/328 (39.94%), Postives = 192/328 (58.54%), Query Frame = 3 
Query:   72 IELHSHIDGSFKPKTILEVGKRRDKILPFKTEEEIKTHLRCDKYKSLRDFLEPFELILPVFKGDKEAVWQMAYDFIEQCAESKTCYVEGRLCPYILADSNLD------------SDLVIKTILDAFSVGKSSFNVESRLIICGLREQAVNMNELLDIAKHWKPHGVVGIDIAGDEQLSMESGGTHETLVKIFKEAEKSGIHRTVHAGENGSSASIREAVYEMHAERIGHGYRVLDDLQLYEDLKKKNIHFETCPSTSFMTGSVAKDP-LQHAIVKFAQDKVNYSINTDDTMMTGRLLDSEMEYASALFDLSSSELNRTRLNAAKSCFL 1016
            +ELH H+DG+ KP+TIL  GK+R   LP  T EE++  +  DK  SL  FL  F+  +PV  G +EA+ ++AY+F+E  A+    YVE R  P++LA+S +D             D V+  +      G+ +F ++ R I+C +R Q     E+L++ K +    VV +D+AGDE  ++E        V+ ++ A K+GIHRTVHAGE GS   +REAV  +  ER+GHGY  ++D  LY  L K+N+HFE CP +S++TG  A DP   HA+V+F  DK NYS+NTDD ++    LD++ +        +  E  R  +NAAKS FL
Sbjct:   12 VELHVHLDGAIKPETILYFGKKRGIALPADTVEELRNIIGMDKPLSLPGFLAKFDYYMPVIAGCREAIKRIAYEFVEMKAKEGVVYVEVRYSPHLLANSKVDPMPWNQTEGDVTPDDVVDLVNQGLQEGEQAFGIKVRSILCCMRHQPSWSLEVLELCKKYNQKTVVAMDLAGDE--TIEGSSLFPGHVEAYEGAVKNGIHRTVHAGEVGSPEVVREAVDILKTERVGHGYHTIEDEALYNRLLKENMHFEVCPWSSYLTG--AWDPKTTHAVVRFKNDKANYSLNTDDPLIFKSTLDTDYQMTKKDMGFTEEEFKRLNINAAKSSFL 335
[Close]
BLAST of Adenosine deaminase vs. Ensembl Mouse
Match: Adal (adenosine deaminase-like [Source:MGI Symbol;Acc:MGI:1923144])

HSP 1 Score: 52.7582 bits (125), Expect = 3.675e-7
Identity = 71/357 (19.89%), Postives = 154/357 (43.14%), Query Frame = 3 
Query:   72 IELHSHIDGSFKPKTILEVGKRRDKILPFKTEEEIKTHLRC---DKYKSLRDFLEPFELILPVFKGDKEAVWQMAYDFIEQCAESKTCYVEGRLCPYILADSNLDSDLVIKTILDAFSVGKS-SFNVESRLIICGLREQAVNM-NELLDIAKHW---KPHGVVGIDIAGDEQLSMESGGTHETLVKIFKEAEKSGIHRTVHAGENGSSASIREAVYEMHAERIGHGYRV-------LDDLQLYEDLKKKNIHFETCPSTSFMTGSVAKDPLQHAIVKFAQDKVNYSINTDDTMMTGRLLDSEMEYASALFDLSSSE---LNRTRLNAAKSCFLDGEEKQNLINHLAEFNIK*NPVKY 1088
            +ELH+H++GS    T+        K++  K    +  H+      K ++L++  + F++I  +     E +  +  D I++ A+    Y+E R  P     + +     ++++L+     K  + +++ R ++   R     +  E +++AK +     + V+G+D++GD  +     G     ++   EA+K+G+   +H  E  +     + +  +  +RIGHG  +       LD +     +++  I  E C +++  + +V      H    ++    +  I TDD  +    L  E + A+  F+L+  +   L+   +N   +C     E +    HL +  +  N V Y
Sbjct:   20 VELHAHLNGSISSSTM-------KKLIAKKPHLNVHGHMTMIDKGKKRTLQECFQMFQVIHQL-TTSAEDILMVTKDVIKEFADDGVKYLELRSTPREENATGMTRKTYVESVLEGIKQCKQENLDIDVRYLMAIDRRGGPTIARETVELAKEFFLSTENTVLGLDLSGDPTI-----GQANDFLEPLLEAKKAGLKLALHLAEIPNREKENQMLLSLLPDRIGHGTFLSASEAGALDQVDF---VRQHQIPLELCLTSNIKSQTVPSYDQHHFGFWYSIAHPSV-ICTDDKGVFATYLSQEYQLAAETFNLTPFQVWDLSYESINYIFACDNTRSELRKRWTHLKQKVLNCNEVNY 359
[Close]
BLAST of Adenosine deaminase vs. Ensembl Mouse
Match: Adal (adenosine deaminase-like [Source:MGI Symbol;Acc:MGI:1923144])

HSP 1 Score: 52.7582 bits (125), Expect = 3.675e-7
Identity = 71/357 (19.89%), Postives = 154/357 (43.14%), Query Frame = 3 
Query:   72 IELHSHIDGSFKPKTILEVGKRRDKILPFKTEEEIKTHLRC---DKYKSLRDFLEPFELILPVFKGDKEAVWQMAYDFIEQCAESKTCYVEGRLCPYILADSNLDSDLVIKTILDAFSVGKS-SFNVESRLIICGLREQAVNM-NELLDIAKHW---KPHGVVGIDIAGDEQLSMESGGTHETLVKIFKEAEKSGIHRTVHAGENGSSASIREAVYEMHAERIGHGYRV-------LDDLQLYEDLKKKNIHFETCPSTSFMTGSVAKDPLQHAIVKFAQDKVNYSINTDDTMMTGRLLDSEMEYASALFDLSSSE---LNRTRLNAAKSCFLDGEEKQNLINHLAEFNIK*NPVKY 1088
            +ELH+H++GS    T+        K++  K    +  H+      K ++L++  + F++I  +     E +  +  D I++ A+    Y+E R  P     + +     ++++L+     K  + +++ R ++   R     +  E +++AK +     + V+G+D++GD  +     G     ++   EA+K+G+   +H  E  +     + +  +  +RIGHG  +       LD +     +++  I  E C +++  + +V      H    ++    +  I TDD  +    L  E + A+  F+L+  +   L+   +N   +C     E +    HL +  +  N V Y
Sbjct:   20 VELHAHLNGSISSSTM-------KKLIAKKPHLNVHGHMTMIDKGKKRTLQECFQMFQVIHQL-TTSAEDILMVTKDVIKEFADDGVKYLELRSTPREENATGMTRKTYVESVLEGIKQCKQENLDIDVRYLMAIDRRGGPTIARETVELAKEFFLSTENTVLGLDLSGDPTI-----GQANDFLEPLLEAKKAGLKLALHLAEIPNREKENQMLLSLLPDRIGHGTFLSASEAGALDQVDF---VRQHQIPLELCLTSNIKSQTVPSYDQHHFGFWYSIAHPSV-ICTDDKGVFATYLSQEYQLAAETFNLTPFQVWDLSYESINYIFACDNTRSELRKRWTHLKQKVLNCNEVNY 359
[Close]
BLAST of Adenosine deaminase vs. UniProt/SwissProt
Match: sp|Q6DG22|ADA_DANRE (Adenosine deaminase OS=Danio rerio OX=7955 GN=ada PE=2 SV=2)

HSP 1 Score: 259.61 bits (662), Expect = 1.386e-82
Identity = 135/341 (39.59%), Postives = 202/341 (59.24%), Query Frame = 3 
Query:   72 IELHSHIDGSFKPKTILEVGKRRDKILPFKTEEEIKTHLRCDKYKSLRDFLEPFELILPVFKGDKEAVWQMAYDFIEQCAESKTCYVEGRLCPYILADSNLDS------------DLVIKTILDAFSVGKSSFNVESRLIICGLREQAVNMNELLDIAKHWKPHGVVGIDIAGDEQLSMESGGTHETLVKIFKEAEKSGIHRTVHAGENGSSASIREAVYEMHAERIGHGYRVLDDLQLYEDLKKKNIHFETCPSTSFMTGSVAKDPLQHAIVKFAQDKVNYSINTDDTMMTGRLLDSEMEYASALFDLSSSELNRTRLNAAKSCFLDGEEKQNLINHLAE 1058
            +ELH H+DG+ + KT+L+V KRR   LP   EEE+K     ++  +L +FL  F   + V  GD+EA+ ++AY+F+E  A+    YVE R  P+ LA+  ++             D V+  +   F  G+ +F  ++R I+C +R       E++++ K +   GVV ID+AGDE ++ ES   H+   K F+EA +S +HRTVHAGE G ++ +REAV  + AERIGHGY  L+D  LY+ L  +N+HFE CP +S +TG+   D  +H ++ F +DK NYS+NTDD  +    L+S+ E      D +  E  R  +NAAKSCFL  +EK+ L+N L E
Sbjct:   12 VELHVHLDGAIRLKTVLDVAKRRGISLPVSMEEELKELCTVNEPATLTEFLGKFSHFMHVIAGDREAIKRIAYEFVETKAKEGVIYVEARYSPHFLANKGVEPLPWDQKPGDITPDDVVDLVNQGFKEGEQAFKTKARSILCCMRHMPNWSMEVVELCKKFHKDGVVAIDLAGDESMNCESYPGHK---KAFEEAVRSNVHRTVHAGEVGPASVVREAVEVLKAERIGHGYHTLEDQNLYKQLLHQNMHFEMCPVSSRLTGACEPDFTKHPLITFKKDKANYSLNTDDPTIFNSTLNSDYEVVQKYMDFTEEEFKRLNINAAKSCFLPEKEKEKLLNQLYE 349
[Close]
BLAST of Adenosine deaminase vs. UniProt/SwissProt
Match: sp|Q63ZU0|ADA_XENTR (Adenosine deaminase OS=Xenopus tropicalis OX=8364 GN=ada PE=2 SV=1)

HSP 1 Score: 254.988 bits (650), Expect = 7.953e-81
Identity = 135/341 (39.59%), Postives = 200/341 (58.65%), Query Frame = 3 
Query:   72 IELHSHIDGSFKPKTILEVGKRRDKILPFKTEEEIKTHLRCDKYKSLRDFLEPFELILPVFKGDKEAVWQMAYDFIEQCAESKTCYVEGRLCPYILADSNLDS------------DLVIKTILDAFSVGKSSFNVESRLIICGLREQAVNMNELLDIAKHWKPHGVVGIDIAGDEQLSMESGGTHETLVKIFKEAEKSGIHRTVHAGENGSSASIREAVYEMHAERIGHGYRVLDDLQLYEDLKKKNIHFETCPSTSFMTGSVAKDPLQHAIVKFAQDKVNYSINTDDTMMTGRLLDSEMEYASALFDLSSSELNRTRLNAAKSCFLDGEEKQNLINHLAE 1058
            +ELH H+DGS KP+TI+   K+R   LP  T E +  H+   +  SL +FL  F   +P   GD+EA+ ++AY+F+E  A+    YVE R  P+ LA+S ++             D V+  +      G+ +FN+++R I+C +R       E++++ K ++   VV ID+AGDE L+ ES   H    K ++EA K GIHRTVHAGE G S+ ++EAV  + AERIGHGY   +D  LY++L +KN+HFE CP +S++TG+   D  +H   +F +DK NYS+NTDD ++ G  LD +   A+     +  E  R  +NAAKS FL   EK+ L+  L E
Sbjct:   11 VELHVHLDGSIKPETIIHFAKKRQIKLPADTVEGLLEHVSYKEPLSLTEFLSKFNHYMPAIAGDREAIKRIAYEFVEMKAKEGVIYVEVRYSPHFLANSKVEPIPWGQKEGDITPDEVVDLVNQGLRKGEKAFNIKARSILCCMRHMPSWSTEVVELCKKYQNDTVVAIDLAGDESLNCESYPGHR---KAYEEAVKCGIHRTVHAGEVGPSSVVKEAVEVLKAERIGHGYHTTEDPNLYKELLEKNMHFEVCPWSSYLTGACHPDFTKHPATQFRKDKANYSLNTDDPLIFGSTLDVDYSIAAKHMGFTEEEFKRVNINAAKSSFLPESEKKELLYKLYE 348
[Close]
BLAST of Adenosine deaminase vs. UniProt/SwissProt
Match: sp|P56658|ADA_BOVIN (Adenosine deaminase OS=Bos taurus OX=9913 GN=ADA PE=1 SV=3)

HSP 1 Score: 254.603 bits (649), Expect = 1.619e-80
Identity = 133/339 (39.23%), Postives = 203/339 (59.88%), Query Frame = 3 
Query:   72 IELHSHIDGSFKPKTILEVGKRRDKILPFKTEEEIKTHLRCDKYKSLRDFLEPFELILPVFKGDKEAVWQMAYDFIEQCAESKTCYVEGRLCPYILADS------------NLDSDLVIKTILDAFSVGKSSFNVESRLIICGLREQAVNMNELLDIAKHWKPHGVVGIDIAGDEQLSMESGGTHETLVKIFKEAEKSGIHRTVHAGENGSSASIREAVYEMHAERIGHGYRVLDDLQLYEDLKKKNIHFETCPSTSFMTGSVAKDPLQHAIVKFAQDKVNYSINTDDTMMTGRLLDSEMEYASALFDLSSSELNRTRLNAAKSCFLDGEEKQNLINHL 1052
            +ELH H+DG+ KP+TIL  G++R   LP  T EE++  +  DK  SL +FL  F+  +P   G +EAV ++AY+F+E  A+    YVE R  P++LA+S            +L  D V+  +      G+  F V+ R I+C +R Q    +E++++ K ++   VV ID+AGDE  ++E        VK + EA KSG+HRTVHAGE GS+  ++EAV  +  ER+GHGY  L+D  LY  L+++N+HFE CP +S++TG+   D  +H +V+F  D+VNYS+NTDD ++    LD++ +        +  E  R  +NAAKS FL  +EK+ L++ L
Sbjct:   12 VELHVHLDGAIKPETILYYGRKRGIALPADTPEELQNIIGMDKPLSLPEFLAKFDYYMPAIAGCREAVKRIAYEFVEMKAKDGVVYVEVRYSPHLLANSKVEPIPWNQAEGDLTPDEVVSLVNQGLQEGERDFGVKVRSILCCMRHQPSWSSEVVELCKKYREQTVVAIDLAGDE--TIEGSSLFPGHVKAYAEAVKSGVHRTVHAGEVGSANVVKEAVDTLKTERLGHGYHTLEDATLYNRLRQENMHFEVCPWSSYLTGAWKPD-TEHPVVRFKNDQVNYSLNTDDPLIFKSTLDTDYQMTKNEMGFTEEEFKRLNINAAKSSFLPEDEKKELLDLL 347
[Close]
BLAST of Adenosine deaminase vs. UniProt/SwissProt
Match: sp|Q5ZKP6|ADA_CHICK (Adenosine deaminase OS=Gallus gallus OX=9031 GN=ADA PE=2 SV=1)

HSP 1 Score: 253.062 bits (645), Expect = 5.559e-80
Identity = 132/341 (38.71%), Postives = 202/341 (59.24%), Query Frame = 3 
Query:   72 IELHSHIDGSFKPKTILEVGKRRDKILPFKTEEEIKTHLRCDKYKSLRDFLEPFELILPVFKGDKEAVWQMAYDFIEQCAESKTCYVEGRLCPYILAD------------SNLDSDLVIKTILDAFSVGKSSFNVESRLIICGLREQAVNMNELLDIAKHWKPHGVVGIDIAGDEQLSMESGGTHETLVKIFKEAEKSGIHRTVHAGENGSSASIREAVYEMHAERIGHGYRVLDDLQLYEDLKKKNIHFETCPSTSFMTGSVAKDPLQHAIVKFAQDKVNYSINTDDTMMTGRLLDSEMEYASALFDLSSSELNRTRLNAAKSCFLDGEEKQNLINHLAE 1058
            +ELH H+DG+ +P+TIL  GK+R   LP  T +E+  H+      SL+ FLE F   +P   GD+EAV ++AY+ +E  A+    YVE R  P++LA+             +L  + V+  +      G+ +F +++R I+C +R       E++++ K ++ + VV ID+AGDE L   S   H+     ++EAE+ GIHRTVHAGE G +  I+EAVY + AERIGHGY VL+D +LY +L +  +HFE CP +S++TG+   D  +H +V+F +D+ NYSINTDD ++    +D +        D +  +  R  +NAA+S FL  +EKQ L+N L E
Sbjct:   13 VELHIHLDGAIRPETILHFGKKRGVPLPGSTVDELMKHVSYQTPLSLKLFLEKFNHYMPAIAGDREAVRRIAYELVETKAKEGVVYVEVRYSPHLLANCRVEPIPWGQAEGDLTPEEVVNLVNQGLQDGERNFRIKARSILCCMRHMPSWSPEVVELCKKYQNNSVVAIDLAGDELLMASS--DHKA---AYEEAERCGIHRTVHAGEAGPATMIKEAVYLLKAERIGHGYHVLEDPELYRELLRTRMHFEVCPWSSYLTGACLPDFRKHPVVQFKKDQANYSINTDDPLIFNSNIDKDYGIVKEYMDFTEEDFKRVNINAAQSSFLPEKEKQELLNTLYE 348
[Close]
BLAST of Adenosine deaminase vs. UniProt/SwissProt
Match: sp|Q6GP70|ADA_XENLA (Adenosine deaminase OS=Xenopus laevis OX=8355 GN=ada PE=2 SV=1)

HSP 1 Score: 249.595 bits (636), Expect = 9.457e-79
Identity = 132/341 (38.71%), Postives = 198/341 (58.06%), Query Frame = 3 
Query:   72 IELHSHIDGSFKPKTILEVGKRRDKILPFKTEEEIKTHLRCDKYKSLRDFLEPFELILPVFKGDKEAVWQMAYDFIEQCAESKTCYVEGRLCPYILADSNLDS------------DLVIKTILDAFSVGKSSFNVESRLIICGLREQAVNMNELLDIAKHWKPHGVVGIDIAGDEQLSMESGGTHETLVKIFKEAEKSGIHRTVHAGENGSSASIREAVYEMHAERIGHGYRVLDDLQLYEDLKKKNIHFETCPSTSFMTGSVAKDPLQHAIVKFAQDKVNYSINTDDTMMTGRLLDSEMEYASALFDLSSSELNRTRLNAAKSCFLDGEEKQNLINHLAE 1058
            +ELH H+DGS KP+TI+   K+R   LP  T E +  H+   +  SL +FL+ F   +P   GD+EA+ ++AY+F+E  A+    YVE R  P+ LA+S +D             D V+  +      G+ +FN+++R I+C +R      +E++++ K ++   VV ID+AGDE L+ ES   H    K ++EA K GIHRTVHAGE G  + ++EAV  + AERIGHGY   +D  LY++L + N+HFE CP +S++T +   D  +H   +F +DK N+S+NTDD ++ G  LD +   A      +  E  R  +NAAKS FL   EK+ L+  L E
Sbjct:   11 VELHVHLDGSIKPETIIHFAKKRQIKLPADTVEGLLEHVSYKEPLSLTEFLQKFNHYMPAIAGDREAIKRIAYEFVEMKAKEGVIYVEVRYSPHFLANSKVDPIPWGQKEGDITPDEVVDLVNQGLRKGEKTFNIKARSILCCMRHMPNWSSEVIELCKKYQNDTVVAIDLAGDESLNCESYPGHR---KAYEEAVKCGIHRTVHAGEVGPPSVVKEAVEVLKAERIGHGYHTTEDPNLYKELLENNMHFEVCPWSSYLTSACHPDFTKHPATQFRKDKANFSLNTDDPLIFGSTLDVDYSIAVQHMGFTEDEFKRVNINAAKSSFLPDNEKKELLYKLYE 348
[Close]
BLAST of Adenosine deaminase vs. TrEMBL
Match: A0A0R3UHM7 (A_deaminase domain-containing protein OS=Mesocestoides corti OX=53468 GN=MCOS_LOCUS6858 PE=4 SV=1)

HSP 1 Score: 292.738 bits (748), Expect = 3.251e-93
Identity = 144/339 (42.48%), Postives = 214/339 (63.13%), Query Frame = 3 
Query:   45 MIFDPKFYNIELHSHIDGSFKPKTILEVGKRRDKILPFKTEEEIKTHLRCDKYKSLRDFLEPFELILPVFKGDKEAVWQMAYDFIEQCAE-SKTCYVEGRLCPYILADSNLDSDLVIKTILDAFSVGKSSFNVESRLIICGLREQAVNMNELLDIAKHWKPHGVVGIDIAGDEQLSMESGGTHETLVKIFKEAEKSGIHRTVHAGENGSSASIREAVYEMHAERIGHGYRVLDDLQLYEDLKKKNIHFETCPSTSFMTGSVAKDPLQHAIVKFAQDKVNYSINTDDTMMTGRLLDSEMEYASALFDLSSSELNRTRLNAAKSCFLDGEEKQNLINHLAE 1058
            M  D   + +ELH H+DGSF+P T+ ++ K R  +LP K+ EE    L+  +  +L + L  F+ I P+  GD+EA+ Q   DF+E C + S  CYVE RL P++L       + V+KT+L+A     + FN+ESRLI+  LR Q    +E++ +AK ++PHGV  ID+AGD+    +   T   + + F+EA  SG+HRTVHAG +G SAS+REA+Y+M AERIGHGY V+DD  LY D+ +KNIHFE CP + +++GSV +    H I++F  D+ N SINTDD  +TG+    E+        L+S+++ R  +NAA++ FL   EK+ L+ H+A+
Sbjct:    1 MHLDGSRHAVELHLHVDGSFRPSTMFQIAKHRGLLLPAKSSEEFSNFLKIHERGNLPELLSKFDCITPIVAGDEEAISQCMTDFLEDCVKKSHLCYVEARLAPHLLVGGGCSVEQVVKTVLEAMLSAATRFNIESRLILTMLRHQPQYASEVISLAKAFQPHGVCAIDLAGDDT-PCDGTNTDLAVKEAFREAYLSGVHRTVHAGVDGPSASVREAIYDMFAERIGHGYHVIDDPALYMDVLEKNIHFEMCPLSGWLSGSVPESWRSHPIIQFFGDQGNVSINTDDPTLTGQWRQQEIAMCLTDLGLTSTQIERANINAAQAAFLADVEKEELLGHIAK 338
[Close]
BLAST of Adenosine deaminase vs. TrEMBL
Match: A0A1S3HXF8 (adenosine deaminase-like isoform X1 OS=Lingula unguis OX=7574 GN=LOC106158711 PE=4 SV=2)

HSP 1 Score: 290.812 bits (743), Expect = 5.119e-92
Identity = 144/344 (41.86%), Postives = 215/344 (62.50%), Query Frame = 3 
Query:   60 KFYNIELHSHIDGSFKPKTILEVGKRRDKILPFKTEEEIKTHLRCDKYKSLRDFLEPFELILPVFKGDKEAVWQMAYDFIEQCAESKTCYVEGRLCPYILAD-----------SNLDSDLVIKTILDAFSVGKSSFNVESRLIICGLREQAVNMNELLDIAKHWKPHGVVGIDIAGDEQLSMESGGTHETLVKIFKEAEKSGIHRTVHAGENGSSASIREAVYEMHAERIGHGYRVLDDLQLYEDLKKKNIHFETCPSTSFMTGSVAKDPLQHAIVKFAQDKVNYSINTDDTMMTGRLLDSEMEYASALFDLSSSELNRTRLNAAKSCFLDGEEKQNLINHLAE 1058
            K   ++LH H+DG+ +  TI +VGKRR+  LP  + EE++ HL      SL +FL  F + +PV  GD EA+ ++AY+F E C+     Y E R CP++LA+            N+    V+K +      G   FN++ + I+C +RE+     E+LD+   +K  GVV ID+AGDE L ++   +H+  +++F+EAE  G+ RTVHAGENG +  +REAVY+MHA+R+GHGY VLDD  LY+ +++K +HFE CP +S MTGSV+ D  +H I++FA+D VN+S+NTDD ++ G  L SE E  +    LS  ++    LNAA++ FL  +EKQ+L+  L E
Sbjct:   29 KMKKVDLHVHLDGAVRASTIWDVGKRRNMSLPGSSVEELQEHLTITDRGSLTEFLAVFAIHMPVICGDLEAIERVAYEFCEDCSNDNIIYCEARYCPHLLANDMENPFYADTKGNVSPLEVVKAVNRGLKKGCVDFNIKVKTILCCMRERPEWAQEILDLCLKFKDQGVVAIDLAGDENLDLKDIKSHDEHLRVFQEAEWLGLSRTVHAGENGPAEIVREAVYDMHAQRLGHGYHVLDDETLYKAVREKGVHFEACPVSSHMTGSVSTDWTKHPILRFARDGVNFSVNTDDPLLIGGFLSSEYETCTEKIGLSLEQIRNANLNAARATFLPEDEKQSLLKQLQE 372
[Close]
BLAST of Adenosine deaminase vs. TrEMBL
Match: A0A183A6W5 (A_deaminase domain-containing protein OS=Echinostoma caproni OX=27848 GN=ECPE_LOCUS2700 PE=4 SV=1)

HSP 1 Score: 285.419 bits (729), Expect = 2.331e-90
Identity = 148/339 (43.66%), Postives = 220/339 (64.90%), Query Frame = 3 
Query:   45 MIFDPKFYNIELHSHIDGSFKPKTILEVGKRRDKILPFKTEEEIKTHLRCDKYKSLRDFLEPFELILPVFKGDK-EAVWQMAYDFIEQCA-ESKTCYVEGRLCPYILADSNLDSDLVIKTILDAFSVGKSSFNVESRLIICGLREQAVNMNELLDIAKHWKPHGVVGIDIAGDEQLSMESGGTHETLVKIFKEAEKSGIHRTVHAGENGSSASIREAVYEMHAERIGHGYRVLDDLQLYEDLKKKNIHFETCPSTSFMTGSVAKDPLQHAIVKFAQDKVNYSINTDDTMMTGRLLDSEMEYASALFDLSSSELNRTRLNAAKSCFLDGEE-KQNLINHL 1052
            M  D     +ELH H+DGS +P TI E+ +R+   L F     ++  L+  +   L  FL  FE ILPVF+GDK EA+ +++ +F+E C   S  CYVE R  P+ LA + + +D     +L+A +      NV+ RLI+C LR++  N  E+LD+A+ ++PHGVVGID+AGDE   M +  + E +V++F+ A+  GIHRTVHAGENG + ++  AV ++HAERIGHGY VL+D+ + + +K+KNIHFE CP++S MTG+ AK    H +  FA   +NYSINTDD  +TGR LD E+++      + S++L   ++NAA++ FLD EE ++ L+NH+
Sbjct:    1 MQLDSSLKRVELHVHLDGSPRPNTIFELAQRKGIKLSFANSVALENALQPKEPYYLGHFLRSFEYILPVFEGDKKEAIARLSEEFVEDCKIRSNLCYVETRFSPHSLAGNRMSADEATTVVLEALTRAAVKHNVQVRLILCILRDKPENAFEVLDLARKYRPHGVVGIDLAGDEGKWMTTKFSDE-IVQVFEHAKSEGIHRTVHAGENGPACAVENAVKQLHAERIGHGYSVLNDVHILDFVKQKNIHFELCPTSSLMTGA-AKRGSVHPLHHFASAGMNYSINTDDPTITGRWLDQELQFCVDGLSV-SADLQEAQINAAQAAFLDVEEDREALVNHV 336
[Close]
BLAST of Adenosine deaminase vs. TrEMBL
Match: A0A1I8FX80 (A_deaminase domain-containing protein OS=Macrostomum lignano OX=282301 PE=4 SV=1)

HSP 1 Score: 284.263 bits (726), Expect = 4.875e-90
Identity = 134/333 (40.24%), Postives = 203/333 (60.96%), Query Frame = 3 
Query:   63 FYNIELHSHIDGSFKPKTILEVGKRRDKILPFKTEEEIKTHLRCDKYKSLRDFLEPFELILPVFKGDKEAVWQMAYDFIEQCAESKTCYVEGRLCPYILADSNLDSDLVIKTILDAFSVGKSSFNVESRLIICGLREQAVNMNELLDIAKHWKPHGVVGIDIAGDEQLSMESGGTHETLVKIFKEAEKSGIHRTVHAGENGSSASIREAVYEMHAERIGHGYRVLDDLQLYEDLKKKNIHFETCPSTSFMTGSVAKDPLQHAIVKFAQDKVNYSINTDDTMMTGRLLDSEMEYASALFDLSSSELNRTRLNAAKSCFLDGEEKQNLINHLAEF 1061
             + +ELH H++G+ +P T+L+V +RR    P  T E     LR     SL +FL  F  ++    GD+EA+ Q+A DF+  CA +  CYVE R CP + A+S L ++ V++ +L+ F VG +   V+ R I+C LR      +E L +AK +  HGVVG+D+AGD++    +GGT   L+++F++A  +G+HRTVHAGEN  SA + EA+ +M+AERIGHGY  LDD  +Y+ + ++ +H E CP +S +TG+V  D   H + +FA D+ +YSIN+DD   TG+ L  E    +    L   EL +   NAA + FL  EE+Q L+  L ++
Sbjct:    6 LHRVELHCHLEGALRPATVLQVARRRGLKAPADTPEAFAEFLRRKSPSSLAEFLAYFPQLVEFAAGDREAIGQLAQDFVADCASNCVCYVESRFCPSLFANSELSAEGVLRAVLEGFEVGSARHGVKVRAILCALRNDPDGSSETLTLAKAYSTHGVVGVDLAGDDRADELAGGTSPKLIELFRQASAAGLHRTVHAGENSGSALVSEALDKMNAERIGHGYHCLDDPAVYQQILQRRVHLEVCPLSSRLTGAVLSDWPHHPVHRFASDRASYSINSDDPTFTGQWLAEEYRLCAEQVGLPPWELVKANYNAAWASFLPDEERQLLLGQLNDY 338
[Close]
BLAST of Adenosine deaminase vs. TrEMBL
Match: A0A4E0RHP4 (Adenosine deaminase OS=Fasciola hepatica OX=6192 GN=D915_002442 PE=4 SV=1)

HSP 1 Score: 282.722 bits (722), Expect = 3.212e-89
Identity = 144/339 (42.48%), Postives = 210/339 (61.95%), Query Frame = 3 
Query:   45 MIFDPKFYNIELHSHIDGSFKPKTILEVGKRRDKILPFKTEEEIKTHLRCDKYKSLRDFLEPFELILPVFKGDKEAVWQMAYDFIEQCA-ESKTCYVEGRLCPYILADSNLDSDLVIKTILDAFSVGKSSFNVESRLIICGLREQAVNMNELLDIAKHWKPHGVVGIDIAGDEQLSMESGGTHETLVKIFKEAEKSGIHRTVHAGENGSSASIREAVYEMHAERIGHGYRVLDDLQLYEDLKKKNIHFETCPSTSFMTGSV-AKDPLQHAIVKFAQDKVNYSINTDDTMMTGRLLDSEMEYASALFDLSSSELNRTRLNAAKSCFLDGEEKQ-NLINHL 1052
            M  + +   +ELH H+DG+ +  T+  +  RR+ + P ++ EE +  L   K   L +FLEPF+LIL    GDKEA+ Q+A + +E C   SK CYVE R  P++L    LDSD V + +L+A  +    + ++ RL++C LR++     E+L++A  ++ HGVVGID++GD+  +    G    ++ +FKEA K  IHRTVHAGEN  + ++ EAV  +HAERIGHGY V+   ++YE L+   +HFE CP++S MTG V  K    H +V+FA+D V YSINTD  +MTGR L  E +Y      L++ +L  T+LNAAK+ FLD EE    LI H+
Sbjct:    1 MNLNEELRGVELHIHLDGAVRADTLYNLALRRNLVGPSRSHEEFRKSLIPTKPYKLANFLEPFKLILLTLAGDKEAIMQVAEECVEDCVLRSKLCYVELRFAPHLLTGPGLDSDAVTRAVLEAVKISSRRYGIQVRLLLCVLRQKPETAEEVLELAIKYRDHGVVGIDVSGDDA-TWRDYGLSPKIIGVFKEAHKRHIHRTVHAGENSPAEAVLEAVSCLHAERIGHGYSVIQQPEIYEWLRNTPVHFEVCPTSSVMTGGVNLKSTSLHPVVQFAKDNVKYSINTDGPLMTGRWLQEEYQYCLNELGLTARDLEVTKLNAAKAAFLDEEEDHIRLIEHI 338
[Close]
BLAST of Adenosine deaminase vs. Ensembl Cavefish
Match: ada (adenosine deaminase [Source:NCBI gene;Acc:103045910])

HSP 1 Score: 242.662 bits (618), Expect = 9.344e-77
Identity = 125/339 (36.87%), Postives = 198/339 (58.41%), Query Frame = 3 
Query:   72 IELHSHIDGSFKPKTILEVGKRRDKILPFKTEEEIKTHLRCDKYKSLRDFLEPFELILPVFKGDKEAVWQMAYDFIEQCAESKTCYVEGRLCPYILADSNLDS------------DLVIKTILDAFSVGKSSFNVESRLIICGLREQAVNMNELLDIAKHWKPHGVVGIDIAGDEQLSMESGGTHETLVKIFKEAEKSGIHRTVHAGENGSSASIREAVYEMHAERIGHGYRVLDDLQLYEDLKKKNIHFETCPSTSFMTGSVAKDPLQHAIVKFAQDKVNYSINTDDTMMTGRLLDSEMEYASALFDLSSSELNRTRLNAAKSCFLDGEEKQNLINHL 1052
            +ELH H+DG+ + +TI++V KRR   L   T EE+   +   +  SL +FL  F   + V  GD+EA+ ++AY+F+E  ++    YVE R  P+ +A+ ++D             D V+  +      G+ +F  ++R I+C +R       +++++ K ++  GVV ID+AGDE L+ E    H   +  + EA KSGIHRTVHAGE G+++ ++EAV  + AERIGHGY  +DD +LY+ L K  +HFE CP +S +TG+   D  +H +++F +DK N+S+NTDD  +    L+S+ +        +  +     +NAAKSCFL   EK+ L+NHL
Sbjct:   21 VELHVHLDGAIRIETIMDVAKRRGIPLSADTVEELTRQITVTEPSSLTEFLGKFSKFMHVIAGDREAIKRIAYEFVETKSKEGVIYVEARYSPHFMANCDVDPIPWDQEKGDLTPDEVVNLVNQGLKEGEEAFKTKARSILCCMRHMPNWSMDVVELCKKYRNDGVVAIDLAGDESLNCEMYPGH---LNAYTEAVKSGIHRTVHAGEVGAASVVKEAVEILKAERIGHGYHTIDDKELYQQLLKDRMHFEMCPVSSRLTGACDPDFTKHPLIRFKEDKANFSLNTDDPTVFNSTLESDYQAVKKYMGFTEEDFRDLNINAAKSCFLPDNEKEELLNHL 356
[Close]
BLAST of Adenosine deaminase vs. Ensembl Cavefish
Match: adal (adenosine deaminase like [Source:NCBI gene;Acc:103033087])

HSP 1 Score: 63.5438 bits (153), Expect = 8.931e-11
Identity = 80/350 (22.86%), Postives = 152/350 (43.43%), Query Frame = 3 
Query:   54 DPKFYN----IELHSHIDGSFKPKTILEVGKRRDKILPFKTEEEIKTHLRCDKYKSLRDFLEPFELILPVFKGDKEAVWQMAYDFIEQCAESKTCYVEGRLCPYILADSNLDSDLVIKTILDAFSVGKS-SFNVESRLIICGLREQAVNMN-ELLDIAKHW--KPHGVV-GIDIAGDEQLSMESGGTHETLVKIFKEAEKSGIHRTVHAGENGSSASIREAVYEMHAERIGHGYRVLDDL----QLYEDLKKKNIHFETCPSTSFMTGSVAKDPLQHAIVKFAQDKVNYSINTDDTMMTGRLLDSEMEYASALFDLSSSELNRTRLNAAKSCFLDGEEKQNLINHLAEFN 1064
            DP FY     +ELH+H++GS   +T+ ++  R+ ++      E   T +R  + ++L +  + F++I  +   + E +  +A   I++ A     Y+E R  P     + L     ++T+++A    K    +++ R ++   R     +  E + +A+ +    +GVV G+D++GD  +     G    L+   ++A   G+   +H  E  S     E + ++  +RIGHG  +  ++     L + + K+ I  E C  TS +TG       QH    +        + TDD  +    L  E + A++ F LS  ++      A    F     KQ L    A+  
Sbjct:    6 DP-FYRQLPKVELHAHLNGSVSSETMEQLIARKPQL----NIEHSMTAIRSGQRRTLDECFQVFKVIHQLVDSE-EDILMVAKAVIQEFAADGVKYLELRSTPREETKTGLSKRRYVETVIEAIHQCKQEGVDIDVRFLVAIDRRNGTKVAMETVKLAEDFMLSSNGVVVGLDLSGDPTV-----GHGRDLLPALQKARNCGLKLALHLSEIPSQKEESELLLDLPPDRIGHGTFLHPEVGGSDTLVDKVCKQKIPIELC-LTSNVTGQTVPSYDQHHFKYWYTRGHPCVLCTDDKGVFCTDLSQEYQLAASTFRLSQEDVWDLSQQAIHCSFAPEPVKQQLEQKWAKLR 343
[Close]
BLAST of Adenosine deaminase vs. Ensembl Sea Lamprey
Match: adal (adenosine deaminase-like [Source:NCBI gene;Acc:619263])

HSP 1 Score: 58.151 bits (139), Expect = 9.030e-10
Identity = 76/331 (22.96%), Postives = 140/331 (42.30%), Query Frame = 3 
Query:   75 ELHSHIDGSFKPKTILEVGKRRDKILPFKTEEEIKTHLRCDKYKSLRDFLEPFELILPVFKGDKEAVWQMAYDFIEQCAESKTCYVEGRLCPYILADSNLDSDLVIKTILDAFSVGKSSF-NVESRLIICGLREQ--AVNMNELLDIAKHWKPHG--VVGIDIAGDEQLSMESGGTHETLVKIFKEAEKSGIHRTVHAGENGSSASIREAVYEMHAERIGHGYRVLDDLQLYEDLKKKNIHFET----CPSTSFMTGSVAKDPLQHAIVKFAQDKVNYSINTDDTMMTGRLLDSEMEYASALFDLSSSELNRTRLNAAKSCFLDGEEKQNL 1040
            ELH+HI+GS    T+ ++  ++    P    +   T ++  + +SL +  E F++I  +   + E++  +  D I +  +    Y+E R  P  L    L     +  +L A    K     ++ R ++   R    AV M  +    +H    G  V+G+D++GD      S G     + + + A+K+G+   +H  E  S       + ++  +RIGHG  +  D+   +++    IH +T    C +++    +VA     H    + +      I TDD  +    L  E   A+  F+LS  +L      +    FL   EK+ L
Sbjct:   17 ELHAHINGSISEATMEKLMHKK----PHLNVQHSMTMIKKGQQRSLEECFEMFKVIHQLTDCE-ESIVMVTKDVIREFHQDGVKYLELRSTPS-LTWPGLTRRSYVDAVLSAIRQSKEELPGIDVRFLLAIDRRNGPAVAMETVKLAEEHLLSSGALVLGLDMSGDP-----SVGHGRDFLPVLEYAKKAGLKLALHLSEIPSQTEETRILMDLPPDRIGHGTFLHPDVGGSQEIVDLIIHHQTPIELCLTSNVKGKTVATYDQHHFRFWYGRGHPCI-ICTDDKGVFATDLSQEYHIAADTFNLSKEDLWNISYRSIDCIFLPEGEKRQL 335
[Close]
BLAST of Adenosine deaminase vs. Ensembl Yeast
Match: AAH1 (Adenine deaminase (adenine aminohydrolase); converts adenine to hypoxanthine; involved in purine salvage; transcriptionally regulated by nutrient levels and growth phase; Aah1p degraded upon entry into quiescence via SCF and the proteasome [Source:SGD;Acc:S000005085])

HSP 1 Score: 82.8037 bits (203), Expect = 4.085e-18
Identity = 86/348 (24.71%), Postives = 147/348 (42.24%), Query Frame = 3 
Query:   75 ELHSHIDGSFKPKTILEVGKRRDKILP---FKTEEEIKTHLRCDKYKSLRDFLEPFELILPVFKGDKEAVWQMAYDFIEQCAESKTCYVEGRLCPYILADSNLDSDLVIKTILDAFSVGKSSFNVESRLIICGLREQAVNMNELLDIAKHWKPH------GVVGIDIAG---DEQLSMESGGTHETLVKIFKEAEKSGIHRTVHAGENGSSASIREAVYEMHAERIGHGYRVLDDLQLYEDLKKKNIHFETCPSTSF---MTGSVAKDPLQHAIVKFAQDKVNYSINTDD-TMMTGRLLDSEMEYASALFDLSSSELNRTRLNAAKSCFLDGEEKQNLINHLAEFNIK 1070
            E H H++G+ +P  +  + KR D ILP    K+ EE+    +  K++ L+DFL+ + +   V   +++  + +A+ + ++  +    + E    P       +  + V K    A     S F + S+LI+C LR   +   E L   +   P         +G+D A       L +E  G   +L K  K         T HAGE G +  + +A+  +   RI HG     D +L + L +       CP ++    +  SV++ PLQ    KF    V +S+N+DD     G +LD   + +            R   NA K  + D + K  L++ + E   K
Sbjct:   14 EHHLHLEGTLEPDLLFPLAKRNDIILPEGFPKSVEELNEKYK--KFRDLQDFLDYYYIGTNVLISEQD-FFDLAWAYFKKVHKQGLVHAEVFYDPQSHTSRGISIETVTKGFQRACDKAFSEFGITSKLIMCLLRH--IEPEECLKTIEEATPFIKDGTISALGLDSAEKPFPPHLFVECYGKAASLNKDLK--------LTAHAGEEGPAQFVSDALDLLQVTRIDHGINSQYDEELLDRLSRDQTMLTICPLSNVKLQVVQSVSELPLQ----KFLDRDVPFSLNSDDPAYFGGYILDVYTQVSKDFPHWDHETWGRIAKNAIKGSWCDDKRKNGLLSRVDEVVTK 344
[Close]
BLAST of Adenosine deaminase vs. Ensembl Nematostella
Match: EDO45463 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RSR8])

HSP 1 Score: 241.121 bits (614), Expect = 9.751e-77
Identity = 128/329 (38.91%), Postives = 201/329 (61.09%), Query Frame = 3 
Query:   72 IELHSHIDGSFKPKTILEVGKRRDKILPFKTEEEIKTHLRCD--KYKSLRDFLEPFELILPVFKGDKEAVWQMAYDFIEQCAESKTCYVEGRLCPYILADSNLDSDLVIKTILDAFSVGKSSFNVESRLIICGLREQAVNMNELLDIAKHWKPHGVVGIDIAGDEQLSMESGGTHETLVKIFKEAEKSGIHRTVHAGENGSSASIREAVYEMHAERIGHGYRVLDDLQLYEDLKKKNIHFETCPSTSFMTGSVAKDPLQHAIVKFAQDKVNYSINTDDTMMTGRLLDSEMEYASALFDLSSSELNRTRLNAAKSCFLDGEEKQNLINHL 1052
            +ELH H+DG+ +  TI+++ ++++  LP   E +++ ++        SLR FL+ F + +    GD  A+ ++AY+F E  A +   Y E R  P+ILA  ++  D V++ +   F  G+  F V +R I+C +R +     E++++ + +K  GVVGID+AGDE L  E+  T +  V  F+EA + GIHRTVHAGE G +AS+REA+ ++HAERIGHGY  L+D +LY+ + K+ IH ETCP++S +TG+V      H I+KFA+D  N+S+N+DD ++    +++E   A     L   +  +  LNAAK+ FL   EK  LI HL
Sbjct:   11 VELHVHLDGALRISTIIDLARKKNIKLPTYDETKLRDYVSVSLKHPSSLRKFLQCFGVFIKTIVGDLNAIERIAYEFCEDQARNGVIYFEARYSPHILATEDVTPDEVVEAVNQGFLRGQVDFRVVARSILCCMRHEPDWSLEVVELCEKFKEAGVVGIDLAGDESLG-ETPAT-KNHVMAFEEARRVGIHRTVHAGEAGPAASVREALDQLHAERIGHGYHTLEDEELYDRVLKERIHLETCPTSSILTGAVPPPFKCHPILKFARDGANFSLNSDDPLVCDTTIENEYRVAHDEIGLGEEDFKKATLNAAKASFLPDYEKLELIKHL 337
[Close]
BLAST of Adenosine deaminase vs. Ensembl Medaka
Match: ada (adenosine deaminase [Source:NCBI gene;Acc:101166382])

HSP 1 Score: 249.98 bits (637), Expect = 2.614e-79
Identity = 128/341 (37.54%), Postives = 204/341 (59.82%), Query Frame = 3 
Query:   72 IELHSHIDGSFKPKTILEVGKRRDKILPFKTEEEIKTHLRCDKYKSLRDFLEPFELILPVFKGDKEAVWQMAYDFIEQCAESKTCYVEGRLCPYILAD------------SNLDSDLVIKTILDAFSVGKSSFNVESRLIICGLREQAVNMNELLDIAKHWKPHGVVGIDIAGDEQLSMESGGTHETLVKIFKEAEKSGIHRTVHAGENGSSASIREAVYEMHAERIGHGYRVLDDLQLYEDLKKKNIHFETCPSTSFMTGSVAKDPLQHAIVKFAQDKVNYSINTDDTMMTGRLLDSEMEYASALFDLSSSELNRTRLNAAKSCFLDGEEKQNLINHLAE 1058
            +ELH H+DG+ + +TIL+V +RR   LP  T +++K  +   + ++L  FLE F+  + V  GD+EA+ ++AY+F+E  A+    YVE R  P++L++             NL  D V++ +    S G+ +F +++R I+C +R       E++++ K ++  GVVGID+AGDE L+ E+   H    K ++EA + GIHRTVHAGE G ++ +REAV  + AER+GHGY  L D  LY +L  +++HFE CP +S +TG+   D  +H ++ F +DK NYS+NTDD ++    L+ +   A      +  E  R  + +AKSCFL  +EK  L++ L E
Sbjct:   43 VELHVHLDGAIRVQTILDVARRRGISLPATTAQQMKERIILQEPETLTGFLEKFDEYMHVVAGDREAIQRIAYEFVEDKAKEGVVYVEARYSPHLLSNCKVEPIPWNQKEGNLCPDEVVRLVNKGLSEGERAFQIKARSILCCMRHMPSWSQEVVELCKKYQNEGVVGIDLAGDESLNCEANPDHR---KAYEEAVRCGIHRTVHAGEVGPASVVREAVEVLKAERVGHGYGTLGDPDLYRELLAQDMHFEVCPFSSKLTGACNPDFTKHPVITFMRDKANYSLNTDDPLIFNSTLNLDYFLAHKHMGFTEEEFKRLNIKSAKSCFLPEKEKNELLSRLYE 380
[Close]
BLAST of Adenosine deaminase vs. Ensembl Medaka
Match: ada (adenosine deaminase [Source:NCBI gene;Acc:101166382])

HSP 1 Score: 229.565 bits (584), Expect = 1.325e-71
Identity = 117/316 (37.03%), Postives = 188/316 (59.49%), Query Frame = 3 
Query:   72 IELHSHIDGSFKPKTILEVGKRRDKILPFKTEEEIKTHLRCDKYKSLRDFLEPFELILPVFKGDKEAVWQMAYDFIEQCAESKTCYVEGRLCPYILAD------------SNLDSDLVIKTILDAFSVGKSSFNVESRLIICGLREQAVNMNELLDIAKHWKPHGVVGIDIAGDEQLSMESGGTHETLVKIFKEAEKSGIHRTVHAGENGSSASIREAVYEMHAERIGHGYRVLDDLQLYEDLKKKNIHFETCPSTSFMTGSVAKDPLQHAIVKFAQDKVNYSINTDDTMMTGRLLDSEMEYASALFDLSSSELNR 983
            +ELH H+DG+ + +TIL+V +RR   LP  T +++K  +   + ++L  FLE F+  + V  GD+EA+ ++AY+F+E  A+    YVE R  P++L++             NL  D V++ +    S G+ +F +++R I+C +R       E++++ K ++  GVVGID+AGDE L+ E+   H    K ++EA + GIHRTVHAGE G ++ +REAV  + AER+GHGY  L D  LY +L  +++HFE CP +S +TG+   D  +H ++ F +DK NYS+NTDD ++    L+ +   A      +  E  R
Sbjct:   43 VELHVHLDGAIRVQTILDVARRRGISLPATTAQQMKERIILQEPETLTGFLEKFDEYMHVVAGDREAIQRIAYEFVEDKAKEGVVYVEARYSPHLLSNCKVEPIPWNQKEGNLCPDEVVRLVNKGLSEGERAFQIKARSILCCMRHMPSWSQEVVELCKKYQNEGVVGIDLAGDESLNCEANPDHR---KAYEEAVRCGIHRTVHAGEVGPASVVREAVEVLKAERVGHGYGTLGDPDLYRELLAQDMHFEVCPFSSKLTGACNPDFTKHPVITFMRDKANYSLNTDDPLIFNSTLNLDYFLAHKHMGFTEEEFKR 355
[Close]
BLAST of Adenosine deaminase vs. Ensembl Medaka
Match: adal (adenosine deaminase like [Source:NCBI gene;Acc:101169693])

HSP 1 Score: 65.4698 bits (158), Expect = 2.009e-11
Identity = 80/340 (23.53%), Postives = 148/340 (43.53%), Query Frame = 3 
Query:   48 IFDPKFYNIELHSHIDGSFKPKTILEVGKRRDKILPFKTEEEIKTHLRCDKYKSLRDFLEPFELILPVFKGDKEAVWQMAYDFIEQCAESKTCYVEGRLCPYILADSNLDSDLVIKTILDAFSVGKS-SFNVESRLIICGLREQAVNMN-ELLDIAKHWKPHG---VVGIDIAGDEQLSMESGGTHETLVKIFKEAEKSGIHRTVHAGENGSSASIREAVYEMHAERIGHGYRVLDDL----QLYEDLKKKNIHFETCPSTSFMTGSVAKDPLQHAIVKFAQDKVNYSINTDDTMMTGRLLDSEMEYASALFDLSSSELNRTRLNAAKSCFLDGEEKQNL 1040
            +F  +   +ELH+H++GS   +T+ ++  R+    P    E   T +   + ++L +  E F++I  +   + E +  ++ D I + AE    Y+E R  P     + L     I TI+ A    KS   +++ RL++   R   + +  E + +A+ +       VVGID++GD  +     G  +  +   + A+  G+  ++H  E  S     E +  +  +RIGHG  +  ++     L + + K  I  E C +++    +V    L H    + Q      I TDD  +    L  E +  ++ F LS  E+ +    A    F +   KQ L
Sbjct:    6 VFYRELPKVELHAHLNGSVSFQTMEKLMNRK----PHLNIEHSMTAIGKGQRRTLDECFEVFKVIHKLVDTE-EDILMVSKDVIREFAEDGVKYLELRSTPREEQRTGLTKTNYIDTIIKAIQQCKSEGLDIDVRLLVAIDRRNGMEVAMETVKLAEEFMLSSDGLVVGIDLSGDPTV-----GHGKYFLPALERAKNGGLKLSLHLSEVQSQLEESELLLNLPPDRIGHGTFLHPEMGGSQSLVDKVVKNGIPLELCLTSNIKGQTVPMFSLHH-FKYWYQLGHPTVICTDDKGVFCTDLSQEYQLVASTFGLSQKEMWKLSQQAIDCIFAEEAVKQQL 334
[Close]
BLAST of Adenosine deaminase vs. Planmine SMEST
Match: SMESG000022051.1 (SMESG000022051.1)

HSP 1 Score: 704.131 bits (1816), Expect = 0.000e+0
Identity = 338/342 (98.83%), Postives = 341/342 (99.71%), Query Frame = 3 
Query:   45 MIFDPKFYNIELHSHIDGSFKPKTILEVGKRRDKILPFKTEEEIKTHLRCDKYKSLRDFLEPFELILPVFKGDKEAVWQMAYDFIEQCAESKTCYVEGRLCPYILADSNLDSDLVIKTILDAFSVGKSSFNVESRLIICGLREQAVNMNELLDIAKHWKPHGVVGIDIAGDEQLSMESGGTHETLVKIFKEAEKSGIHRTVHAGENGSSASIREAVYEMHAERIGHGYRVLDDLQLYEDLKKKNIHFETCPSTSFMTGSVAKDPLQHAIVKFAQDKVNYSINTDDTMMTGRLLDSEMEYASALFDLSSSELNRTRLNAAKSCFLDGEEKQNLINHLAEFNIK 1070
            MIFDPKFYNIELHSHIDGSFKPKTILEVGKRRDKILPFKTEEEIKTHLRCDKYKSLRDFLEPFELILPVFKGDKEAVWQMAYDFIEQCAESKTCYVEGRLCPYILADSNLDSDLVIKTILDAFSVGKSSFNVESRLIICGLREQAVNMNELLDIAKHWKPHGVVGIDIAGDEQLSMESGGTHETLVKIFKEAEKSGIHRTVHAGENGSSASIREAVYEMHAERIGHGYRVLDDLQLYEDLKKKNIHFETCPSTSFMTGSV+KDPLQHAIVKF+QDKVNYSINTDDTMMTGRLLDSEMEYASALFDLS+SELNRTRLNAAKSCFLDGEEKQ LINHLAEFNIK
Sbjct:    1 MIFDPKFYNIELHSHIDGSFKPKTILEVGKRRDKILPFKTEEEIKTHLRCDKYKSLRDFLEPFELILPVFKGDKEAVWQMAYDFIEQCAESKTCYVEGRLCPYILADSNLDSDLVIKTILDAFSVGKSSFNVESRLIICGLREQAVNMNELLDIAKHWKPHGVVGIDIAGDEQLSMESGGTHETLVKIFKEAEKSGIHRTVHAGENGSSASIREAVYEMHAERIGHGYRVLDDLQLYEDLKKKNIHFETCPSTSFMTGSVSKDPLQHAIVKFSQDKVNYSINTDDTMMTGRLLDSEMEYASALFDLSASELNRTRLNAAKSCFLDGEEKQYLINHLAEFNIK 342
[Close]
BLAST of Adenosine deaminase vs. Planmine SMEST
Match: SMESG000068461.1 (SMESG000068461.1)

HSP 1 Score: 187.193 bits (474), Expect = 3.609e-58
Identity = 86/161 (53.42%), Postives = 116/161 (72.05%), Query Frame = 3 
Query:  570 MESGGTHETLVKIFKEAEKSGIHRTVHAGENGSSASIREAVYEMHAERIGHGYRVLDDLQLYEDLKKKNIHFETCPSTSFMTGSVAKDPLQHAIVKFAQDKVNYSINTDDTMMTGRLLDSEMEYASALFDLSSSELNRTRLNAAKSCFLDGEEKQNLINHL 1052
            ME  GTH+ ++++F  A++ GIHRT+HAGENG    I EAV E+HAERIGHGY +L +  LY++L+ KNIHFE CP++SF+TGSV+ DP  H    F +DKVNYSIN DD M+TGR L  E ++    F++SS E+ R   NAA+S FL+ +EK  L++HL
Sbjct:    1 MECNGTHKGIIELFNRAKREGIHRTIHAGENGPVRMIEEAVNELHAERIGHGYSILKNDALYQELRSKNIHFEICPTSSFLTGSVSTDPNCHPFHTFCKDKVNYSINCDDIMITGRNLKEEHKFCKEKFNISSEEIKRITFNAARSSFLEPQEKSYLLHHL 161
[Close]
BLAST of Adenosine deaminase vs. Planmine SMEST
Match: SMESG000068458.1 (SMESG000068458.1)

HSP 1 Score: 153.295 bits (386), Expect = 5.988e-45
Identity = 72/170 (42.35%), Postives = 112/170 (65.88%), Query Frame = 3 
Query:   45 MIFDPKFYNIELHSHIDGSFKPKTILEVGKRRDKILPFKTEEEIKTHLRCDKYKSLRDFLEPFELILPVFKGDKEAVWQMAYDFIEQCAESKTCYVEGRLCPYILADSNLDSDLVIKTILDAFSVGKSSFNVESRLIICGLREQAVNMNELLDIAKHWKPHGVVGIDIAG 554
            M F+P F  +ELH+H+DGS K +TI ++ +R+   +P    E +K  L+  + KSLR+FL  F+ +LP+ +GD EA+ ++ ++F++  AES+ CYVE R  P  LA   L SD V++T+LDA  +   +F V +++I+C LR+  +     LD+A  +KPHGVVGID+AG
Sbjct:    1 MKFNPNFKYVELHNHLDGSIKAETIHKICQRKCLDMPHSNVESLKDFLKLKEPKSLREFLLKFDTVLPIVQGDTEAIAEVCHEFVKMAAESEVCYVETRFYPQSLASPGLSSDAVVRTVLDALRIADETFGVVTKVILCSLRQLELVDPNCLDLAIKYKPHGVVGIDLAG 170
The following BLAST results are available for this feature:
BLAST of Adenosine deaminase vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ADA2.427e-7738.35adenosine deaminase [Source:HGNC Symbol;Acc:HGNC:1... [more]
ADA5.678e-6033.63adenosine deaminase [Source:HGNC Symbol;Acc:HGNC:1... [more]
ADA2.639e-5439.29adenosine deaminase [Source:HGNC Symbol;Acc:HGNC:1... [more]
ADA1.290e-945.76adenosine deaminase [Source:HGNC Symbol;Acc:HGNC:1... [more]
ADAL4.736e-720.31adenosine deaminase like [Source:HGNC Symbol;Acc:H... [more]
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BLAST of Adenosine deaminase vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 3
Match NameE-valueIdentityDescription
C06G3.51.852e-6335.88pep chromosome:WBcel235:IV:7026472:7028121:1 gene:... [more]
C06G3.54.989e-6335.88pep chromosome:WBcel235:IV:7024211:7028144:1 gene:... [more]
C44B7.123.064e-924.36Adenosine deaminase-like protein [Source:UniProtK... [more]
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BLAST of Adenosine deaminase vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 1
Match NameE-valueIdentityDescription
Ada7.255e-1020.71gene:FBgn0037661 transcript:FBtr0081971[more]
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BLAST of Adenosine deaminase vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 3
Match NameE-valueIdentityDescription
ada2.076e-8339.59adenosine deaminase [Source:NCBI gene;Acc:436919][more]
adal1.779e-1223.08adenosine deaminase-like [Source:NCBI gene;Acc:619... [more]
adal1.779e-1223.08adenosine deaminase-like [Source:NCBI gene;Acc:619... [more]
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BLAST of Adenosine deaminase vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ada2.709e-7538.30adenosine deaminase [Source:NCBI gene;Acc:496434][more]
ada6.583e-7237.43adenosine deaminase [Source:NCBI gene;Acc:496434][more]
ada.22.668e-7134.69adenosine deaminase, gene 2 [Source:NCBI gene;Acc:... [more]
ada.24.732e-7134.90adenosine deaminase, gene 2 [Source:NCBI gene;Acc:... [more]
ada.25.116e-6335.18adenosine deaminase, gene 2 [Source:NCBI gene;Acc:... [more]
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BLAST of Adenosine deaminase vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 3
Match NameE-valueIdentityDescription
Ada4.688e-7639.94adenosine deaminase [Source:MGI Symbol;Acc:MGI:879... [more]
Adal3.675e-719.89adenosine deaminase-like [Source:MGI Symbol;Acc:MG... [more]
Adal3.675e-719.89adenosine deaminase-like [Source:MGI Symbol;Acc:MG... [more]
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BLAST of Adenosine deaminase vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q6DG22|ADA_DANRE1.386e-8239.59Adenosine deaminase OS=Danio rerio OX=7955 GN=ada ... [more]
sp|Q63ZU0|ADA_XENTR7.953e-8139.59Adenosine deaminase OS=Xenopus tropicalis OX=8364 ... [more]
sp|P56658|ADA_BOVIN1.619e-8039.23Adenosine deaminase OS=Bos taurus OX=9913 GN=ADA P... [more]
sp|Q5ZKP6|ADA_CHICK5.559e-8038.71Adenosine deaminase OS=Gallus gallus OX=9031 GN=AD... [more]
sp|Q6GP70|ADA_XENLA9.457e-7938.71Adenosine deaminase OS=Xenopus laevis OX=8355 GN=a... [more]
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BLAST of Adenosine deaminase vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A0R3UHM73.251e-9342.48A_deaminase domain-containing protein OS=Mesocesto... [more]
A0A1S3HXF85.119e-9241.86adenosine deaminase-like isoform X1 OS=Lingula ung... [more]
A0A183A6W52.331e-9043.66A_deaminase domain-containing protein OS=Echinosto... [more]
A0A1I8FX804.875e-9040.24A_deaminase domain-containing protein OS=Macrostom... [more]
A0A4E0RHP43.212e-8942.48Adenosine deaminase OS=Fasciola hepatica OX=6192 G... [more]
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BLAST of Adenosine deaminase vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 2
Match NameE-valueIdentityDescription
ada9.344e-7736.87adenosine deaminase [Source:NCBI gene;Acc:10304591... [more]
adal8.931e-1122.86adenosine deaminase like [Source:NCBI gene;Acc:103... [more]
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BLAST of Adenosine deaminase vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1
Match NameE-valueIdentityDescription
adal9.030e-1022.96adenosine deaminase-like [Source:NCBI gene;Acc:619... [more]
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BLAST of Adenosine deaminase vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 1
Match NameE-valueIdentityDescription
AAH14.085e-1824.71Adenine deaminase (adenine aminohydrolase); conver... [more]
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BLAST of Adenosine deaminase vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1
Match NameE-valueIdentityDescription
EDO454639.751e-7738.91Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Adenosine deaminase vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 3
Match NameE-valueIdentityDescription
ada2.614e-7937.54adenosine deaminase [Source:NCBI gene;Acc:10116638... [more]
ada1.325e-7137.03adenosine deaminase [Source:NCBI gene;Acc:10116638... [more]
adal2.009e-1123.53adenosine deaminase like [Source:NCBI gene;Acc:101... [more]
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BLAST of Adenosine deaminase vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 3
Match NameE-valueIdentityDescription
SMESG000022051.10.000e+098.83SMESG000022051.1[more]
SMESG000068461.13.609e-5853.42SMESG000068461.1[more]
SMESG000068458.15.988e-4542.35SMESG000068458.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30008618 ID=SMED30008618|Name=Adenosine deaminase|organism=Schmidtea mediterranea sexual|type=transcript|length=1169bp
TAAGAAGCTAAATAACGTATTACTTAATTTATGAAAGTTTGAATATGATA
TTCGATCCAAAGTTTTATAATATTGAATTACATAGTCATATTGATGGATC
ATTCAAACCAAAAACGATTTTGGAAGTAGGGAAAAGGAGAGATAAAATAT
TGCCCTTTAAAACAGAGGAAGAGATAAAAACTCATCTTCGATGTGACAAA
TATAAATCTTTACGAGATTTTTTAGAACCATTTGAATTAATTTTGCCAGT
TTTTAAAGGTGATAAGGAGGCTGTTTGGCAAATGGCATACGATTTTATTG
AGCAATGTGCCGAATCGAAGACTTGTTATGTTGAAGGACGGTTATGTCCT
TATATTTTAGCTGATTCAAATCTAGACTCTGATCTAGTTATTAAAACAAT
TCTTGATGCTTTTTCGGTGGGTAAAAGTTCTTTTAATGTGGAATCGAGAT
TAATCATTTGTGGGTTGCGAGAACAAGCAGTCAATATGAATGAACTTCTT
GACATTGCAAAACATTGGAAACCTCATGGCGTAGTTGGTATTGATATAGC
TGGAGACGAACAATTATCCATGGAATCTGGAGGAACTCATGAAACATTGG
TAAAGATTTTCAAAGAAGCTGAAAAATCGGGAATACATCGAACTGTACAT
GCAGGAGAAAATGGATCTTCTGCATCGATCCGAGAAGCAGTTTATGAAAT
GCACGCTGAGAGAATCGGTCACGGTTATCGTGTCTTGGATGATTTACAGC
TTTATGAAGATCTGAAAAAGAAAAATATTCATTTTGAAACTTGTCCATCA
ACAAGTTTTATGACCGGATCAGTTGCCAAGGACCCGTTGCAACACGCAAT
TGTAAAATTTGCTCAAGATAAAGTAAACTATTCTATTAATACCGATGACA
CAATGATGACTGGACGTTTATTGGATTCGGAAATGGAATATGCTTCCGCT
CTTTTTGATCTCTCTTCATCGGAACTTAATCGAACAAGACTCAACGCTGC
GAAATCTTGTTTTCTTGACGGCGAAGAGAAACAAAATTTGATAAACCATT
TAGCGGAGTTCAATATTAAATAAAATCCGGTTAAATATTCACAAGTTAAG
GTTTTGTTGAAACCGATGATTATGTAATTTTAAAATTTTGTTTAAATCAT
TTTTATGTGAATATTACGC
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protein sequence of SMED30008618-orf-1

>SMED30008618-orf-1 ID=SMED30008618-orf-1|Name=SMED30008618-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=343bp
MIFDPKFYNIELHSHIDGSFKPKTILEVGKRRDKILPFKTEEEIKTHLRC
DKYKSLRDFLEPFELILPVFKGDKEAVWQMAYDFIEQCAESKTCYVEGRL
CPYILADSNLDSDLVIKTILDAFSVGKSSFNVESRLIICGLREQAVNMNE
LLDIAKHWKPHGVVGIDIAGDEQLSMESGGTHETLVKIFKEAEKSGIHRT
VHAGENGSSASIREAVYEMHAERIGHGYRVLDDLQLYEDLKKKNIHFETC
PSTSFMTGSVAKDPLQHAIVKFAQDKVNYSINTDDTMMTGRLLDSEMEYA
SALFDLSSSELNRTRLNAAKSCFLDGEEKQNLINHLAEFNIK*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000016pharynx
PLANA:0000026gut
PLANA:0003116parenchymal cell
Vocabulary: INTERPRO
TermDefinition
IPR006330Ado/ade_deaminase
IPR001365A/AMP_deaminase_dom
IPR032466Metal_Hydrolase
IPR000651Ras-like_Gua-exchang_fac_N
Vocabulary: molecular function
TermDefinition
GO:0019239deaminase activity
GO:0004000adenosine deaminase activity
GO:0016787hydrolase activity
Vocabulary: biological process
TermDefinition
GO:0009168purine ribonucleoside monophosphate biosynthetic process
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR006330Adenosine/adenine deaminaseTIGRFAMTIGR01430TIGR01430coord: 10..335
e-value: 3.0E-80
score: 267.6
IPR001365Adenosine/AMP deaminase domainPFAMPF00962A_deaminasecoord: 10..334
e-value: 3.0E-65
score: 220.7
NoneNo IPR availableGENE3DG3DSA:3.20.20.140coord: 5..341
e-value: 1.1E-86
score: 293.2
NoneNo IPR availablePANTHERPTHR11409ADENOSINE DEAMINASEcoord: 9..338
NoneNo IPR availablePANTHERPTHR11409:SF43ADENOSINE DEAMINASEcoord: 9..338
IPR032466Metal-dependent hydrolaseSUPERFAMILYSSF51556Metallo-dependent hydrolasescoord: 5..337