Sorting nexin-14

Overview
NameSorting nexin-14
Smed IDSMED30008612
Length (bp)3035
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Sorting nexin-14 (SMED30008612) t-SNE clustered cells

Violin plots show distribution of expression levels for Sorting nexin-14 (SMED30008612) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Sorting nexin-14 (SMED30008612) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Sorting nexin-14 (SMED30008612) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30008612

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 8

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
protonephridiaSMED30008612SMESG000057128.1 dd_Smed_v4_6581_1_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
nervous systemSMED30008612SMESG000057128.1 dd_Smed_v4_6581_1_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30008612SMESG000057128.1 dd_Smed_v4_6581_1_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30008612SMESG000057128.1 dd_Smed_v4_6581_1_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cilated neuronSMED30008612SMESG000057128.1 dd_Smed_v4_6581_1_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30008612SMESG000057128.1 Contig48062newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30008612SMESG000057128.1 Contig48062uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
epidermisSMED30008612SMESG000057128.1 dd_Smed_v4_6581_1_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017		whole organism asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Sorting nexin-14 vs. Ensembl Human
Match: SNX14 (sorting nexin 14 [Source:HGNC Symbol;Acc:HGNC:14977])

HSP 1 Score: 151.754 bits (382), Expect = 9.128e-37
Identity = 138/458 (30.13%), Postives = 217/458 (47.38%), Query Frame = 3 
Query: 1644 KQKEFSMTKFGLSIKQVFTANSDDSL-----NLISGDLDIDNPDGSEWLSNSFGDLVDLPD----LSYLRVKIPSI---SQPYVTNKKKGELYFSVYTYKVDSDKLL--------YKVHRKYGEFYVLEQKLLEFHGTIERA-LPPKRPWDNKNLDFLEKCKLEFETYLMYLVNRTFLRNSELLHRFLT---RPTEFSFNSLIDINLGKFVKSMPMIFTKEKGQFLDQFLYNFHISCEASSQAKSNSNNDPYSSLSNSVSDPGSKSLFDARLHTRMYWNNAEL--NTIK--SENFMKDICSFSTRYIFYYFDSLCFFFEIITNKLAYSHFLLNFFYRIRSILVDVFQTYVKGVITRGFEKLCHEKLAVEIIHVLRDAALLSGLN-RTISEKQERRNEALTSLYQLLPGWLSIVLSDDQIKTLYSNIDRIFDFLQQPKLNKQLSYVLFDILLLELFPEL 2930
            + + F +++ G  IK VF + + +        +  G+ D           +S  + V  P+    L+  ++ IP +     P    K+K E    V+   V+ +           + V+R+Y EFYVLE KL EFHG    A LP KR    KN +FL+  + EF+ YL  L+    L NS+LL  FL+     T+F    L D+NLGK +KS+P    KEKGQ L+ F+ NF  SCE+     S     P  ++ +  S+  +K LF+      ++ NNA    NT +  ++N+  ++ +    Y     D L +   ++     + H LL      R +  +  + Y    +    E+L  E   V +I +LRDA        R++ +KQ+   +    +   +P  L   + ++   T Y +I  +FD LQQP LNKQL+YVL DI++ ELFPEL
Sbjct:  444 RGESFGISRIGSKIKGVFKSTTMEGAMLPNYGVAEGEDDFIEEGIVVMEDDSPVEAVSTPNTPRNLAAWKISIPYVDFFEDPSSERKEKKE-RIPVFCIDVERNDRRAVGHEPEHWSVYRRYLEFYVLESKLTEFHGAFPDAQLPSKRIIGPKNYEFLKSKREEFQEYLQKLLQHPELSNSQLLADFLSPNGGETQFLDKILPDVNLGKIIKSVPGKLMKEKGQHLEPFIMNFINSCESPKPKPSR----PELTILSPTSE-NNKKLFND-----LFKNNANRAENTERKQNQNYFMEVMTVEGVY-----DYLMYVGRVVFQVPDWLHHLL---MGTRILFKNTLEMYTDYYLQCKLEQLFQEHRLVSLITLLRDAIFCENTEPRSLQDKQKGAKQTFEEMMNYIPDLLVKCIGEE---TKYESIRLLFDGLQQPVLNKQLTYVLLDIVIQELFPEL 879

HSP 2 Score: 82.4185 bits (202), Expect = 3.006e-15
Identity = 64/300 (21.33%), Postives = 136/300 (45.33%), Query Frame = 3 
Query:  435 FSKISIPELVSQKFLPACINHLDICYTIQXXXXXXXXXLTPVQEILLQKMRSHLHVAMISRSEEVAYLKSISKFLIPLITPDYFSRTKNKISDHLLQECFSGTVLLPAMDSVASPDLINKFIYLLLTPSTISTALCNTQSSYVPILHRYQTAWMEKLKRLEEHPKGIECLRNEKHLYHFLQYIKSVEAVSAVNIYLEMDAIILKLLSPDMDESTKIHIFQDIERFENLIHLSDGKSNLIISSDLRRRIKEAIADGYQNVDRLRNCEIWMENYQLICQHNQSLYLSQYFES-EFFLSTIYG 1331
             S++ IP ++++K L A + H+++    +            +Q+  L++    LHVA+ SR +E+ YL+ +++ L P I P     T  +    L++E  SG+V LP++D +A PD +N  + + +  S    A     S  VP L ++     +K   L+   K I     +  L+ F+ ++K   AV  +   L ++    ++L P++     + + +++++      L +    +     +   I+      Y +V +L+      E Y+ +    ++++   +  S E+F   + G
Sbjct:  137 LSEVDIPSIITKKLLKAAMKHIEVIVKARQKVKNTEF----LQQAALEEYGPELHVALRSRRDELHYLRKLTELLFPYILPP--KATDCRSLTLLIREILSGSVFLPSLDFLADPDTVNHLLIIFIDDSPPEKA-TEPASPLVPFLQKFAEPRNKKPSVLKLELKQIR--EQQDLLFRFMNFLKQEGAVHVLQFCLTVEEFNDRILRPELSNDEMLSLHEELQKIYKTYCLDESIDKIRFDPFIVEEIQRIAEGPYIDVVKLQTMRCLFEAYEHVLSLLENVFTPMFCHSDEYFRQLLRG 427
[Close]
BLAST of Sorting nexin-14 vs. Ensembl Human
Match: SNX14 (sorting nexin 14 [Source:HGNC Symbol;Acc:HGNC:14977])

HSP 1 Score: 151.369 bits (381), Expect = 1.253e-36
Identity = 138/458 (30.13%), Postives = 217/458 (47.38%), Query Frame = 3 
Query: 1644 KQKEFSMTKFGLSIKQVFTANSDDSL-----NLISGDLDIDNPDGSEWLSNSFGDLVDLPD----LSYLRVKIPSI---SQPYVTNKKKGELYFSVYTYKVDSDKLL--------YKVHRKYGEFYVLEQKLLEFHGTIERA-LPPKRPWDNKNLDFLEKCKLEFETYLMYLVNRTFLRNSELLHRFLT---RPTEFSFNSLIDINLGKFVKSMPMIFTKEKGQFLDQFLYNFHISCEASSQAKSNSNNDPYSSLSNSVSDPGSKSLFDARLHTRMYWNNAEL--NTIK--SENFMKDICSFSTRYIFYYFDSLCFFFEIITNKLAYSHFLLNFFYRIRSILVDVFQTYVKGVITRGFEKLCHEKLAVEIIHVLRDAALLSGLN-RTISEKQERRNEALTSLYQLLPGWLSIVLSDDQIKTLYSNIDRIFDFLQQPKLNKQLSYVLFDILLLELFPEL 2930
            + + F +++ G  IK VF + + +        +  G+ D           +S  + V  P+    L+  ++ IP +     P    K+K E    V+   V+ +           + V+R+Y EFYVLE KL EFHG    A LP KR    KN +FL+  + EF+ YL  L+    L NS+LL  FL+     T+F    L D+NLGK +KS+P    KEKGQ L+ F+ NF  SCE+     S     P  ++ +  S+  +K LF+      ++ NNA    NT +  ++N+  ++ +    Y     D L +   ++     + H LL      R +  +  + Y    +    E+L  E   V +I +LRDA        R++ +KQ+   +    +   +P  L   + ++   T Y +I  +FD LQQP LNKQL+YVL DI++ ELFPEL
Sbjct:  488 RGESFGISRIGSKIKGVFKSTTMEGAMLPNYGVAEGEDDFIEEGIVVMEDDSPVEAVSTPNTPRNLAAWKISIPYVDFFEDPSSERKEKKE-RIPVFCIDVERNDRRAVGHEPEHWSVYRRYLEFYVLESKLTEFHGAFPDAQLPSKRIIGPKNYEFLKSKREEFQEYLQKLLQHPELSNSQLLADFLSPNGGETQFLDKILPDVNLGKIIKSVPGKLMKEKGQHLEPFIMNFINSCESPKPKPSR----PELTILSPTSE-NNKKLFND-----LFKNNANRAENTERKQNQNYFMEVMTVEGVY-----DYLMYVGRVVFQVPDWLHHLL---MGTRILFKNTLEMYTDYYLQCKLEQLFQEHRLVSLITLLRDAIFCENTEPRSLQDKQKGAKQTFEEMMNYIPDLLVKCIGEE---TKYESIRLLFDGLQQPVLNKQLTYVLLDIVIQELFPEL 923

HSP 2 Score: 107.071 bits (266), Expect = 6.789e-23
Identity = 73/345 (21.16%), Postives = 161/345 (46.67%), Query Frame = 3 
Query:  300 ALEEIFDIIIANYINSWYLGFSNNEDFIVEIKYFFHTLCAEILLRFSKISIPELVSQKFLPACINHLDICYTIQXXXXXXXXXLTPVQEILLQKMRSHLHVAMISRSEEVAYLKSISKFLIPLITPDYFSRTKNKISDHLLQECFSGTVLLPAMDSVASPDLINKFIYLLLTPSTISTALCNTQSSYVPILHRYQTAWMEKLKRLEEHPKGIECLRNEKHLYHFLQYIKSVEAVSAVNIYLEMDAIILKLLSPDMDESTKIHIFQDIERFENLIHLSDGKSNLIISSDLRRRIKEAIADGYQNVDRLRNCEIWMENYQLICQHNQSLYLSQYFES-EFFLSTIYG 1331
            +L E+ ++++ N++  WY   +++E F+ E++       + ++ R  K+ IP ++++K L A + H+++    +            +Q+  L++    LHVA+ SR +E+ YL+ +++ L P I P     T  +    L++E  SG+V LP++D +A PD +N  + + +  S    A     S  VP L ++     +K   L+   K I     +  L+ F+ ++K   AV  +   L ++    ++L P++     + + +++++      L +    +     +   I+      Y +V +L+      E Y+ +    ++++   +  S E+F   + G
Sbjct:  136 SLSEVLELVLENFVYPWYRDVTDDESFVDELRITLRFFASVLIRRIHKVDIPSIITKKLLKAAMKHIEVIVKARQKVKNTEF----LQQAALEEYGPELHVALRSRRDELHYLRKLTELLFPYILPP--KATDCRSLTLLIREILSGSVFLPSLDFLADPDTVNHLLIIFIDDSPPEKA-TEPASPLVPFLQKFAEPRNKKPSVLKLELKQIR--EQQDLLFRFMNFLKQEGAVHVLQFCLTVEEFNDRILRPELSNDEMLSLHEELQKIYKTYCLDESIDKIRFDPFIVEEIQRIAEGPYIDVVKLQTMRCLFEAYEHVLSLLENVFTPMFCHSDEYFRQLLRG 471
[Close]
BLAST of Sorting nexin-14 vs. Ensembl Human
Match: SNX14 (sorting nexin 14 [Source:HGNC Symbol;Acc:HGNC:14977])

HSP 1 Score: 150.984 bits (380), Expect = 1.309e-36
Identity = 138/458 (30.13%), Postives = 217/458 (47.38%), Query Frame = 3 
Query: 1644 KQKEFSMTKFGLSIKQVFTANSDDSL-----NLISGDLDIDNPDGSEWLSNSFGDLVDLPD----LSYLRVKIPSI---SQPYVTNKKKGELYFSVYTYKVDSDKLL--------YKVHRKYGEFYVLEQKLLEFHGTIERA-LPPKRPWDNKNLDFLEKCKLEFETYLMYLVNRTFLRNSELLHRFLT---RPTEFSFNSLIDINLGKFVKSMPMIFTKEKGQFLDQFLYNFHISCEASSQAKSNSNNDPYSSLSNSVSDPGSKSLFDARLHTRMYWNNAEL--NTIK--SENFMKDICSFSTRYIFYYFDSLCFFFEIITNKLAYSHFLLNFFYRIRSILVDVFQTYVKGVITRGFEKLCHEKLAVEIIHVLRDAALLSGLN-RTISEKQERRNEALTSLYQLLPGWLSIVLSDDQIKTLYSNIDRIFDFLQQPKLNKQLSYVLFDILLLELFPEL 2930
            + + F +++ G  IK VF + + +        +  G+ D           +S  + V  P+    L+  ++ IP +     P    K+K E    V+   V+ +           + V+R+Y EFYVLE KL EFHG    A LP KR    KN +FL+  + EF+ YL  L+    L NS+LL  FL+     T+F    L D+NLGK +KS+P    KEKGQ L+ F+ NF  SCE+     S     P  ++ +  S+  +K LF+      ++ NNA    NT +  ++N+  ++ +    Y     D L +   ++     + H LL      R +  +  + Y    +    E+L  E   V +I +LRDA        R++ +KQ+   +    +   +P  L   + ++   T Y +I  +FD LQQP LNKQL+YVL DI++ ELFPEL
Sbjct:  445 RGESFGISRIGSKIKGVFKSTTMEGAMLPNYGVAEGEDDFIEEGIVVMEDDSPVEAVSTPNTPRNLAAWKISIPYVDFFEDPSSERKEKKE-RIPVFCIDVERNDRRAVGHEPEHWSVYRRYLEFYVLESKLTEFHGAFPDAQLPSKRIIGPKNYEFLKSKREEFQEYLQKLLQHPELSNSQLLADFLSPNGGETQFLDKILPDVNLGKIIKSVPGKLMKEKGQHLEPFIMNFINSCESPKPKPSR----PELTILSPTSE-NNKKLFND-----LFKNNANRAENTERKQNQNYFMEVMTVEGVY-----DYLMYVGRVVFQVPDWLHHLL---MGTRILFKNTLEMYTDYYLQCKLEQLFQEHRLVSLITLLRDAIFCENTEPRSLQDKQKGAKQTFEEMMNYIPDLLVKCIGEE---TKYESIRLLFDGLQQPVLNKQLTYVLLDIVIQELFPEL 880

HSP 2 Score: 107.457 bits (267), Expect = 5.994e-23
Identity = 73/345 (21.16%), Postives = 161/345 (46.67%), Query Frame = 3 
Query:  300 ALEEIFDIIIANYINSWYLGFSNNEDFIVEIKYFFHTLCAEILLRFSKISIPELVSQKFLPACINHLDICYTIQXXXXXXXXXLTPVQEILLQKMRSHLHVAMISRSEEVAYLKSISKFLIPLITPDYFSRTKNKISDHLLQECFSGTVLLPAMDSVASPDLINKFIYLLLTPSTISTALCNTQSSYVPILHRYQTAWMEKLKRLEEHPKGIECLRNEKHLYHFLQYIKSVEAVSAVNIYLEMDAIILKLLSPDMDESTKIHIFQDIERFENLIHLSDGKSNLIISSDLRRRIKEAIADGYQNVDRLRNCEIWMENYQLICQHNQSLYLSQYFES-EFFLSTIYG 1331
            +L E+ ++++ N++  WY   +++E F+ E++       + ++ R  K+ IP ++++K L A + H+++    +            +Q+  L++    LHVA+ SR +E+ YL+ +++ L P I P     T  +    L++E  SG+V LP++D +A PD +N  + + +  S    A     S  VP L ++     +K   L+   K I     +  L+ F+ ++K   AV  +   L ++    ++L P++     + + +++++      L +    +     +   I+      Y +V +L+      E Y+ +    ++++   +  S E+F   + G
Sbjct:   84 SLSEVLELVLENFVYPWYRDVTDDESFVDELRITLRFFASVLIRRIHKVDIPSIITKKLLKAAMKHIEVIVKARQKVKNTEF----LQQAALEEYGPELHVALRSRRDELHYLRKLTELLFPYILPP--KATDCRSLTLLIREILSGSVFLPSLDFLADPDTVNHLLIIFIDDSPPEKA-TEPASPLVPFLQKFAEPRNKKPSVLKLELKQIR--EQQDLLFRFMNFLKQEGAVHVLQFCLTVEEFNDRILRPELSNDEMLSLHEELQKIYKTYCLDESIDKIRFDPFIVEEIQRIAEGPYIDVVKLQTMRCLFEAYEHVLSLLENVFTPMFCHSDEYFRQLLRG 419
[Close]
BLAST of Sorting nexin-14 vs. Ensembl Human
Match: SNX14 (sorting nexin 14 [Source:HGNC Symbol;Acc:HGNC:14977])

HSP 1 Score: 151.369 bits (381), Expect = 1.359e-36
Identity = 138/458 (30.13%), Postives = 217/458 (47.38%), Query Frame = 3 
Query: 1644 KQKEFSMTKFGLSIKQVFTANSDDSL-----NLISGDLDIDNPDGSEWLSNSFGDLVDLPD----LSYLRVKIPSI---SQPYVTNKKKGELYFSVYTYKVDSDKLL--------YKVHRKYGEFYVLEQKLLEFHGTIERA-LPPKRPWDNKNLDFLEKCKLEFETYLMYLVNRTFLRNSELLHRFLT---RPTEFSFNSLIDINLGKFVKSMPMIFTKEKGQFLDQFLYNFHISCEASSQAKSNSNNDPYSSLSNSVSDPGSKSLFDARLHTRMYWNNAEL--NTIK--SENFMKDICSFSTRYIFYYFDSLCFFFEIITNKLAYSHFLLNFFYRIRSILVDVFQTYVKGVITRGFEKLCHEKLAVEIIHVLRDAALLSGLN-RTISEKQERRNEALTSLYQLLPGWLSIVLSDDQIKTLYSNIDRIFDFLQQPKLNKQLSYVLFDILLLELFPEL 2930
            + + F +++ G  IK VF + + +        +  G+ D           +S  + V  P+    L+  ++ IP +     P    K+K E    V+   V+ +           + V+R+Y EFYVLE KL EFHG    A LP KR    KN +FL+  + EF+ YL  L+    L NS+LL  FL+     T+F    L D+NLGK +KS+P    KEKGQ L+ F+ NF  SCE+     S     P  ++ +  S+  +K LF+      ++ NNA    NT +  ++N+  ++ +    Y     D L +   ++     + H LL      R +  +  + Y    +    E+L  E   V +I +LRDA        R++ +KQ+   +    +   +P  L   + ++   T Y +I  +FD LQQP LNKQL+YVL DI++ ELFPEL
Sbjct:  497 RGESFGISRIGSKIKGVFKSTTMEGAMLPNYGVAEGEDDFIEEGIVVMEDDSPVEAVSTPNTPRNLAAWKISIPYVDFFEDPSSERKEKKE-RIPVFCIDVERNDRRAVGHEPEHWSVYRRYLEFYVLESKLTEFHGAFPDAQLPSKRIIGPKNYEFLKSKREEFQEYLQKLLQHPELSNSQLLADFLSPNGGETQFLDKILPDVNLGKIIKSVPGKLMKEKGQHLEPFIMNFINSCESPKPKPSR----PELTILSPTSE-NNKKLFND-----LFKNNANRAENTERKQNQNYFMEVMTVEGVY-----DYLMYVGRVVFQVPDWLHHLL---MGTRILFKNTLEMYTDYYLQCKLEQLFQEHRLVSLITLLRDAIFCENTEPRSLQDKQKGAKQTFEEMMNYIPDLLVKCIGEE---TKYESIRLLFDGLQQPVLNKQLTYVLLDIVIQELFPEL 932

HSP 2 Score: 107.071 bits (266), Expect = 6.620e-23
Identity = 73/345 (21.16%), Postives = 161/345 (46.67%), Query Frame = 3 
Query:  300 ALEEIFDIIIANYINSWYLGFSNNEDFIVEIKYFFHTLCAEILLRFSKISIPELVSQKFLPACINHLDICYTIQXXXXXXXXXLTPVQEILLQKMRSHLHVAMISRSEEVAYLKSISKFLIPLITPDYFSRTKNKISDHLLQECFSGTVLLPAMDSVASPDLINKFIYLLLTPSTISTALCNTQSSYVPILHRYQTAWMEKLKRLEEHPKGIECLRNEKHLYHFLQYIKSVEAVSAVNIYLEMDAIILKLLSPDMDESTKIHIFQDIERFENLIHLSDGKSNLIISSDLRRRIKEAIADGYQNVDRLRNCEIWMENYQLICQHNQSLYLSQYFES-EFFLSTIYG 1331
            +L E+ ++++ N++  WY   +++E F+ E++       + ++ R  K+ IP ++++K L A + H+++    +            +Q+  L++    LHVA+ SR +E+ YL+ +++ L P I P     T  +    L++E  SG+V LP++D +A PD +N  + + +  S    A     S  VP L ++     +K   L+   K I     +  L+ F+ ++K   AV  +   L ++    ++L P++     + + +++++      L +    +     +   I+      Y +V +L+      E Y+ +    ++++   +  S E+F   + G
Sbjct:  136 SLSEVLELVLENFVYPWYRDVTDDESFVDELRITLRFFASVLIRRIHKVDIPSIITKKLLKAAMKHIEVIVKARQKVKNTEF----LQQAALEEYGPELHVALRSRRDELHYLRKLTELLFPYILPP--KATDCRSLTLLIREILSGSVFLPSLDFLADPDTVNHLLIIFIDDSPPEKA-TEPASPLVPFLQKFAEPRNKKPSVLKLELKQIR--EQQDLLFRFMNFLKQEGAVHVLQFCLTVEEFNDRILRPELSNDEMLSLHEELQKIYKTYCLDESIDKIRFDPFIVEEIQRIAEGPYIDVVKLQTMRCLFEAYEHVLSLLENVFTPMFCHSDEYFRQLLRG 471
[Close]
BLAST of Sorting nexin-14 vs. Ensembl Human
Match: SNX14 (sorting nexin 14 [Source:HGNC Symbol;Acc:HGNC:14977])

HSP 1 Score: 128.257 bits (321), Expect = 1.587e-29
Identity = 126/441 (28.57%), Postives = 202/441 (45.80%), Query Frame = 3 
Query: 1644 KQKEFSMTKFGLSIKQVFTANSDDSL-----NLISGDLDIDNPDGSEWLSNSFGDLVDLPD----LSYLRVKIPSI---SQPYVTNKKKGELYFSVYTYKVDSDKLL--------YKVHRKYGEFYVLEQKLLEFHGTIERA-LPPKRPWDNKNLDFLEKCKLEFETYLMYLVNRTFLRNSELLHRFLT---RPTEFSFNSLIDINLGKFVKSMPMIFTKEKGQFLDQFLYNFHISCEASSQAKSNSNNDPYSSLSNSVSDPGSKSLFDARLHTRMYWNNAEL--NTIK--SENFMKDICSFSTRYIFYYFDSLCFFFEIITNKLAYSHFLLNFFYRIRSILVDVFQTYVKGVITRGFEKLCHEKLAVEIIHVLRDAALLSGLN-RTISEKQERRNEALTSLYQLLPGWLSIVLSDDQIKTLYSNIDRIFDFLQQPKLNKQ 2879
            + + F +++ G  IK VF + + +        +  G+ D           +S  + V  P+    L+  ++ IP +     P    K+K E    V+   V+ +           + V+R+Y EFYVLE KL EFHG    A LP KR    KN +FL+  + EF+ YL  L+    L NS+LL  FL+     T+F    L D+NLGK +KS+P    KEKGQ L+ F+ NF  SCE+     S     P  ++ +  S+  +K LF+      ++ NNA    NT +  ++N+  ++ +    Y     D L +   ++     + H LL      R +  +  + Y    +    E+L  E   V +I +LRDA        R++ +KQ+   +    +   +P  L   + ++   T Y +I  +FD LQQP LNKQ
Sbjct:  415 RGESFGISRIGSKIKGVFKSTTMEGAMLPNYGVAEGEDDFIEEGIVVMEDDSPVEAVSTPNTPRNLAAWKISIPYVDFFEDPSSERKEKKE-RIPVFCIDVERNDRRAVGHEPEHWSVYRRYLEFYVLESKLTEFHGAFPDAQLPSKRIIGPKNYEFLKSKREEFQEYLQKLLQHPELSNSQLLADFLSPNGGETQFLDKILPDVNLGKIIKSVPGKLMKEKGQHLEPFIMNFINSCESPKPKPSR----PELTILSPTSE-NNKKLFND-----LFKNNANRAENTERKQNQNYFMEVMTVEGVY-----DYLMYVGRVVFQVPDWLHHLL---MGTRILFKNTLEMYTDYYLQCKLEQLFQEHRLVSLITLLRDAIFCENTEPRSLQDKQKGAKQTFEEMMNYIPDLLVKCIGEE---TKYESIRLLFDGLQQPVLNKQ 833

HSP 2 Score: 107.457 bits (267), Expect = 5.388e-23
Identity = 73/345 (21.16%), Postives = 161/345 (46.67%), Query Frame = 3 
Query:  300 ALEEIFDIIIANYINSWYLGFSNNEDFIVEIKYFFHTLCAEILLRFSKISIPELVSQKFLPACINHLDICYTIQXXXXXXXXXLTPVQEILLQKMRSHLHVAMISRSEEVAYLKSISKFLIPLITPDYFSRTKNKISDHLLQECFSGTVLLPAMDSVASPDLINKFIYLLLTPSTISTALCNTQSSYVPILHRYQTAWMEKLKRLEEHPKGIECLRNEKHLYHFLQYIKSVEAVSAVNIYLEMDAIILKLLSPDMDESTKIHIFQDIERFENLIHLSDGKSNLIISSDLRRRIKEAIADGYQNVDRLRNCEIWMENYQLICQHNQSLYLSQYFES-EFFLSTIYG 1331
            +L E+ ++++ N++  WY   +++E F+ E++       + ++ R  K+ IP ++++K L A + H+++    +            +Q+  L++    LHVA+ SR +E+ YL+ +++ L P I P     T  +    L++E  SG+V LP++D +A PD +N  + + +  S    A     S  VP L ++     +K   L+   K I     +  L+ F+ ++K   AV  +   L ++    ++L P++     + + +++++      L +    +     +   I+      Y +V +L+      E Y+ +    ++++   +  S E+F   + G
Sbjct:   63 SLSEVLELVLENFVYPWYRDVTDDESFVDELRITLRFFASVLIRRIHKVDIPSIITKKLLKAAMKHIEVIVKARQKVKNTEF----LQQAALEEYGPELHVALRSRRDELHYLRKLTELLFPYILPP--KATDCRSLTLLIREILSGSVFLPSLDFLADPDTVNHLLIIFIDDSPPEKA-TEPASPLVPFLQKFAEPRNKKPSVLKLELKQIR--EQQDLLFRFMNFLKQEGAVHVLQFCLTVEEFNDRILRPELSNDEMLSLHEELQKIYKTYCLDESIDKIRFDPFIVEEIQRIAEGPYIDVVKLQTMRCLFEAYEHVLSLLENVFTPMFCHSDEYFRQLLRG 398
[Close]
BLAST of Sorting nexin-14 vs. Ensembl Celegans
Match: snx-14 (Sorting NeXin [Source:UniProtKB/TrEMBL;Acc:G5EF63])

HSP 1 Score: 100.908 bits (250), Expect = 2.267e-21
Identity = 109/355 (30.70%), Postives = 167/355 (47.04%), Query Frame = 3 
Query: 1929 YKVHRKYGEFYVLEQKLLEFHGTIER--ALPPKRPWDNKNLDFLEKCKLEFETYLMYLVNRTFLRNSELLHRFLTRPTEFSFN-SLIDINLGKFVK-SMP-MIFTKEKGQFLDQFLY-NFHISCEASSQAKSNSNNDPYSSLSNSVSDPGSKSLFDARLHTRMYWNNAELNTIKSENFMKDIC-SFSTRYIFYY----FDS-LCFFFEIITNKLAYSHFLLNFFYRIRSILVDVFQTYVKGVITRGFEK-LCHEKLAVEIIHVLRDAALLSGLNRTISEKQERRNEALTSLYQL------LPGWLSIVLSDDQIKTLYSNIDRIFDFLQQPKLNKQLSYVLFDILLLELFPELTD 2936
            + +HR + EFYVLE KL EFHG   R   LP ++ +  ++  F+E+ +L F T+L  L  +  L  SELL  FL+   EF    SL D+N  K VK ++P  +  +EKGQ L  FL      +     + K  S N     L ++ +   S SL    +++ +Y NN +          K+ C S     +  +    +DS L  F++ +  +  ++   L  F  IR++      + +  V+   F K L    L   + H+    +L        +E++ +  E L     L      +P     ++  D IKTL   I RI D LQ P+LNKQL YVL D LLL++FPEL +
Sbjct:  632 WSIHRSFNEFYVLESKLNEFHGDSLRFSPLPTRKTFVTRDKPFMEQHRLIFSTFLSTLSKQRILNRSELLLAFLSSNEEFRDTLSLGDLNPWKVVKKTLPGKLVNREKGQNLKPFLLKTLAQTLVPPDRVKKPSEN----GLEDATT---SYSLATNAVYSSVYGNNFD-------GVFKESCRSLGDEDMRLWTRSAYDSILLLFWQPLKTQFQWA---LPIFSAIRALCSKTIDSMICSVLGGVFRKCLSVANLTYLVQHI--QWSLFCNDAPWPTEQEMKMREELALRITLEFFQNNIPQHARRLIGRDDIKTL---ISRIIDVLQYPRLNKQLLYVLVDRLLLQIFPELDE 964

HSP 2 Score: 83.5741 bits (205), Expect = 5.827e-16
Identity = 100/384 (26.04%), Postives = 164/384 (42.71%), Query Frame = 3 
Query:  300 ALEEIFDIIIANYINSWYLG-FSNNEDFIVEIKYFFHTLCAEILLRFSKISIPELVSQKFLPACINHLDICYTIQXXXXXXXXXLTPVQEILLQKMRSHL---HVAMISRSEEVAYLKSISKFLIPLITPD---------------YFSRTKN------KISDHLLQECFSGTVLLPAMDSVASPDLINKFIYLLLTP-STISTALCNTQSSYVPILHRY--QTAWMEKLKRLEEHPKGIECLRNEKHLYHFLQYIKSVEA--------VSAVNIYLEMDAIILKLLSPDMDESTKIHIFQDIERFENLIHLSDGKSNLIISSDLRRRIKEAIADGYQN---VDRLRNCEIWME-NYQLICQHNQSLYLSQYFESEFFLSTIYG 1331
            A+E + + I+  Y+N WY G  S +  FI EI+Y      A ++    ++ + E VS + LP    ++     I     +   S TP + +L  K+   L   HVA+  R EE AY++ IS FLIP +  +                F R KN      K     L+E  +  VLLP  D +  PD IN ++ LL      +     +  ++ +P+L     ++   + L       K  E LR+ +    F  Y++ +          V A  I   +D+I  KL S   D      I+Q   +F   +H          S+  R RI E++ + Y++   V+ +R  E  +E +YQ +    QS ++  + +SE FL  + G
Sbjct:  118 AVENLLNEIVEQYVNGWYGGAISRDRAFINEIRYQLRYASANLIRCIRRVDLAEFVSDQALPIASFYIT---RINELEQKLRESPTPPRSLLETKIAEQLDDIHVALSGRDEETAYVRQISDFLIPRLLDETRLAGRAHDDDSPLRLFGRGKNERPWPSKSVRGFLREMLTNAVLLPVFDMLTQPDTINYWLILLFDEHRKVEMIEEHVDTTPIPLLKGLTDESGASDNLPDSLLQLKLTEILRDARLYAIFRMYLQDIRGPVHELQFLVEATRI---LDSIQRKLES---DSQIAYDIWQLYGQF---VHE---------SAQERVRIAESLVEQYKSAVEVNDIRVLEGIIEMSYQEVYNRTQSTHVVAFCQSECFLGHLCG 480
[Close]
BLAST of Sorting nexin-14 vs. Ensembl Celegans
Match: snx-14 (Sorting NeXin [Source:UniProtKB/TrEMBL;Acc:G5EF63])

HSP 1 Score: 100.908 bits (250), Expect = 2.267e-21
Identity = 109/355 (30.70%), Postives = 167/355 (47.04%), Query Frame = 3 
Query: 1929 YKVHRKYGEFYVLEQKLLEFHGTIER--ALPPKRPWDNKNLDFLEKCKLEFETYLMYLVNRTFLRNSELLHRFLTRPTEFSFN-SLIDINLGKFVK-SMP-MIFTKEKGQFLDQFLY-NFHISCEASSQAKSNSNNDPYSSLSNSVSDPGSKSLFDARLHTRMYWNNAELNTIKSENFMKDIC-SFSTRYIFYY----FDS-LCFFFEIITNKLAYSHFLLNFFYRIRSILVDVFQTYVKGVITRGFEK-LCHEKLAVEIIHVLRDAALLSGLNRTISEKQERRNEALTSLYQL------LPGWLSIVLSDDQIKTLYSNIDRIFDFLQQPKLNKQLSYVLFDILLLELFPELTD 2936
            + +HR + EFYVLE KL EFHG   R   LP ++ +  ++  F+E+ +L F T+L  L  +  L  SELL  FL+   EF    SL D+N  K VK ++P  +  +EKGQ L  FL      +     + K  S N     L ++ +   S SL    +++ +Y NN +          K+ C S     +  +    +DS L  F++ +  +  ++   L  F  IR++      + +  V+   F K L    L   + H+    +L        +E++ +  E L     L      +P     ++  D IKTL   I RI D LQ P+LNKQL YVL D LLL++FPEL +
Sbjct:  632 WSIHRSFNEFYVLESKLNEFHGDSLRFSPLPTRKTFVTRDKPFMEQHRLIFSTFLSTLSKQRILNRSELLLAFLSSNEEFRDTLSLGDLNPWKVVKKTLPGKLVNREKGQNLKPFLLKTLAQTLVPPDRVKKPSEN----GLEDATT---SYSLATNAVYSSVYGNNFD-------GVFKESCRSLGDEDMRLWTRSAYDSILLLFWQPLKTQFQWA---LPIFSAIRALCSKTIDSMICSVLGGVFRKCLSVANLTYLVQHI--QWSLFCNDAPWPTEQEMKMREELALRITLEFFQNNIPQHARRLIGRDDIKTL---ISRIIDVLQYPRLNKQLLYVLVDRLLLQIFPELDE 964

HSP 2 Score: 83.5741 bits (205), Expect = 5.827e-16
Identity = 100/384 (26.04%), Postives = 164/384 (42.71%), Query Frame = 3 
Query:  300 ALEEIFDIIIANYINSWYLG-FSNNEDFIVEIKYFFHTLCAEILLRFSKISIPELVSQKFLPACINHLDICYTIQXXXXXXXXXLTPVQEILLQKMRSHL---HVAMISRSEEVAYLKSISKFLIPLITPD---------------YFSRTKN------KISDHLLQECFSGTVLLPAMDSVASPDLINKFIYLLLTP-STISTALCNTQSSYVPILHRY--QTAWMEKLKRLEEHPKGIECLRNEKHLYHFLQYIKSVEA--------VSAVNIYLEMDAIILKLLSPDMDESTKIHIFQDIERFENLIHLSDGKSNLIISSDLRRRIKEAIADGYQN---VDRLRNCEIWME-NYQLICQHNQSLYLSQYFESEFFLSTIYG 1331
            A+E + + I+  Y+N WY G  S +  FI EI+Y      A ++    ++ + E VS + LP    ++     I     +   S TP + +L  K+   L   HVA+  R EE AY++ IS FLIP +  +                F R KN      K     L+E  +  VLLP  D +  PD IN ++ LL      +     +  ++ +P+L     ++   + L       K  E LR+ +    F  Y++ +          V A  I   +D+I  KL S   D      I+Q   +F   +H          S+  R RI E++ + Y++   V+ +R  E  +E +YQ +    QS ++  + +SE FL  + G
Sbjct:  118 AVENLLNEIVEQYVNGWYGGAISRDRAFINEIRYQLRYASANLIRCIRRVDLAEFVSDQALPIASFYIT---RINELEQKLRESPTPPRSLLETKIAEQLDDIHVALSGRDEETAYVRQISDFLIPRLLDETRLAGRAHDDDSPLRLFGRGKNERPWPSKSVRGFLREMLTNAVLLPVFDMLTQPDTINYWLILLFDEHRKVEMIEEHVDTTPIPLLKGLTDESGASDNLPDSLLQLKLTEILRDARLYAIFRMYLQDIRGPVHELQFLVEATRI---LDSIQRKLES---DSQIAYDIWQLYGQF---VHE---------SAQERVRIAESLVEQYKSAVEVNDIRVLEGIIEMSYQEVYNRTQSTHVVAFCQSECFLGHLCG 480
[Close]
BLAST of Sorting nexin-14 vs. Ensembl Zebrafish
Match: snx14 (sorting nexin 14 [Source:NCBI gene;Acc:555970])

HSP 1 Score: 159.073 bits (401), Expect = 2.792e-39
Identity = 137/457 (29.98%), Postives = 216/457 (47.26%), Query Frame = 3 
Query: 1644 KQKEFSMTKFGLSIKQVFTANSDDSLNL-----ISGDLDIDNP------DGSEWLSNSFGDLVDLPDLSYLRVKIPSISQPYVTNKKKGELYFSVYTYKVDSDKLLYK-----VHRKYGEFYVLEQKLLEFHGTIERA-LPPKRPWDNKNLDFLEKCKLEFETYLMYLVNRTFLRNSELLHRFLT---RPTEFSFNSLIDINLGKFVKSMPMIFTKEKGQFLDQFLYNFHISCEASSQAKSNSNNDPYSSLSNSVSDPGSKSLFDARLHTRMYWNNAEL----NTIKSENFMKDICSFSTRYIFYYFDSLCFFFEIITNKLAYSHFLLNFFYRIRSILVDVFQTYVKGVITRGFEKLCHEKLAVEIIHVLRDAALL-SGLNRTISEKQERRNEALTSLYQLLPGWLSIVLSDDQIKTLYSNIDRIFDFLQQPKLNKQLSYVLFDILLLELFPELTDN 2939
            + + F +++ G  IK VF +++ +   L     I G+ D          D S    ++ G    L +LS   + IP +       KK+    F +   + D   + ++     V+RKY EFYVLE KL EFHG  + A LP KR    KN +FL   + EFE YL  L++   L NS+LL  FL+     ++F    L D+NLGK  KS+P    KEKGQ L+ F+ +F  SCE+    K   +    + LS +  +  +K LF+      +Y NNA L        ++N+  ++      Y +  +   C    ++     + H LL+    +R +L    + YV        E++  E   V ++ +LRDA    S   R+  +KQ R  +    +   LP  +   + ++     Y  +  +F+ +QQP LNKQ++YVL DI + ELFPEL+ N
Sbjct:  487 RGESFGISRIGSKIKGVFKSSTMEGAMLPQYAMIEGEDDTVEEAVMVFEDDSPGPMDAVGTPGTLRNLSAWTISIPYVDFYDDEVKKERIPVFCIDVERNDRKNVGHETESWSVYRKYVEFYVLESKLTEFHGPFQDAQLPSKRIIGPKNYEFLSSKRGEFEEYLQKLLHHPELSNSQLLADFLSPFSMESQFRDKMLPDVNLGKIFKSVPGKLIKEKGQNLEPFIQSFFSSCES---PKPKPSRPELTILSPTAEN--NKKLFN-----ELYRNNANLPEGLEKKHNQNYFMELMEVDGAYDYMMYIGKC---RVVFRMPDWLHHLLS---GVRILLKRTLEAYVGHYFQYKLEQIMEEHRLVSLVTLLRDAVFCESTEERSPEDKQRRAKQTFEEMMNYLPDIVGKCIGEE---AKYDGVKMLFNTIQQPLLNKQMTYVLLDIAIQELFPELSKN 924

HSP 2 Score: 103.99 bits (258), Expect = 4.669e-22
Identity = 73/323 (22.60%), Postives = 153/323 (47.37%), Query Frame = 3 
Query:  300 ALEEIFDIIIANYINSWYLGFSNNEDFIVEIKYFFHTLCAEILLRFSKISIPELVSQKFLPACINHLDICYTIQXXXXXXXXXLTPVQEILLQKMRSHLHVAMISRSEEVAYLKSISKFLIPLITPDYFSRTKNKISDHLLQECFSGTVLLPAMDSVASPDLINKFIYLLLTPSTISTALCNTQSSYVPILHRYQTAWMEKLKRLEEHPKGIECLRNEKHLYHFLQYIKSVEAVSAVNIYLEMDAIILKLLSPDMDESTKIHIFQDIERFENLIHLSDGKSNLIISSDLRRRIKEAIADG-YQNVDRLRNCEIWMENYQ-LIC 1262
            ++ E+ ++++ N++  WY   +++E  + E++       A +  R  ++ +P +V  K + A + H++I    Q            +++  L +  + LHVA+ SR +E+ YL+ +++ L P + P     T  +    L++E  +G+V LP MD VA PD +N  + + +  S     + +  S+ VP L R+     +K   L+   K I     +  L+ F+ ++K   AV  +   L ++    ++L PD+ +  K  + +++++      L +    +     +   I  +IA+G Y  V +L+      E Y+ ++C
Sbjct:  135 SISEVLELVLENFVYPWYRDITDDEACVDELRQTIRFFAAVLAHRAQRVDVPSVVMDKMMKAAMKHIEIIAKAQQKVRNTDG----LEQAALAEYGADLHVALRSRKDELLYLRKLTELLFPYVMPP--KATDCRSLALLIREVMTGSVFLPIMDFVADPDTVNHMVLIFIDDSP-PEPVTDPPSTLVPFLERFADPRTKKSSVLKLDLKEIR--EQQDLLFRFMSFLKEEGAVHVLQFCLTVEEFNDRILCPDLSDDEKQRLHEEVKKIYETYCLEESIDKISFDPFIIEEI-HSIAEGPYTGVVKLQTMRCLFEAYEHVLC 447
[Close]
BLAST of Sorting nexin-14 vs. Ensembl Zebrafish
Match: snx14 (sorting nexin 14 [Source:NCBI gene;Acc:555970])

HSP 1 Score: 158.303 bits (399), Expect = 5.204e-39
Identity = 137/457 (29.98%), Postives = 216/457 (47.26%), Query Frame = 3 
Query: 1644 KQKEFSMTKFGLSIKQVFTANSDDSLNL-----ISGDLDIDNP------DGSEWLSNSFGDLVDLPDLSYLRVKIPSISQPYVTNKKKGELYFSVYTYKVDSDKLLYK-----VHRKYGEFYVLEQKLLEFHGTIERA-LPPKRPWDNKNLDFLEKCKLEFETYLMYLVNRTFLRNSELLHRFLT---RPTEFSFNSLIDINLGKFVKSMPMIFTKEKGQFLDQFLYNFHISCEASSQAKSNSNNDPYSSLSNSVSDPGSKSLFDARLHTRMYWNNAEL----NTIKSENFMKDICSFSTRYIFYYFDSLCFFFEIITNKLAYSHFLLNFFYRIRSILVDVFQTYVKGVITRGFEKLCHEKLAVEIIHVLRDAALL-SGLNRTISEKQERRNEALTSLYQLLPGWLSIVLSDDQIKTLYSNIDRIFDFLQQPKLNKQLSYVLFDILLLELFPELTDN 2939
            + + F +++ G  IK VF +++ +   L     I G+ D          D S    ++ G    L +LS   + IP +       KK+    F +   + D   + ++     V+RKY EFYVLE KL EFHG  + A LP KR    KN +FL   + EFE YL  L++   L NS+LL  FL+     ++F    L D+NLGK  KS+P    KEKGQ L+ F+ +F  SCE+    K   +    + LS +  +  +K LF+      +Y NNA L        ++N+  ++      Y     D + +   ++     + H LL+    +R +L    + YV        E++  E   V ++ +LRDA    S   R+  +KQ R  +    +   LP  +   + ++     Y  +  +F+ +QQP LNKQ++YVL DI + ELFPEL+ N
Sbjct:  487 RGESFGISRIGSKIKGVFKSSTMEGAMLPQYAMIEGEDDTVEEAVMVFEDDSPGPMDAVGTPGTLRNLSAWTISIPYVDFYDDEVKKERIPVFCIDVERNDRKNVGHETESWSVYRKYVEFYVLESKLTEFHGPFQDAQLPSKRIIGPKNYEFLSSKRGEFEEYLQKLLHHPELSNSQLLADFLSPFSMESQFRDKMLPDVNLGKIFKSVPGKLIKEKGQNLEPFIQSFFSSCES---PKPKPSRPELTILSPTAEN--NKKLFN-----ELYRNNANLPEGLEKKHNQNYFMELMEVDGAY-----DYMMYIGRVVFRMPDWLHHLLS---GVRILLKRTLEAYVGHYFQYKLEQIMEEHRLVSLVTLLRDAVFCESTEERSPEDKQRRAKQTFEEMMNYLPDIVGKCIGEE---AKYDGVKMLFNTIQQPLLNKQMTYVLLDIAIQELFPELSKN 922

HSP 2 Score: 103.99 bits (258), Expect = 4.503e-22
Identity = 73/323 (22.60%), Postives = 153/323 (47.37%), Query Frame = 3 
Query:  300 ALEEIFDIIIANYINSWYLGFSNNEDFIVEIKYFFHTLCAEILLRFSKISIPELVSQKFLPACINHLDICYTIQXXXXXXXXXLTPVQEILLQKMRSHLHVAMISRSEEVAYLKSISKFLIPLITPDYFSRTKNKISDHLLQECFSGTVLLPAMDSVASPDLINKFIYLLLTPSTISTALCNTQSSYVPILHRYQTAWMEKLKRLEEHPKGIECLRNEKHLYHFLQYIKSVEAVSAVNIYLEMDAIILKLLSPDMDESTKIHIFQDIERFENLIHLSDGKSNLIISSDLRRRIKEAIADG-YQNVDRLRNCEIWMENYQ-LIC 1262
            ++ E+ ++++ N++  WY   +++E  + E++       A +  R  ++ +P +V  K + A + H++I    Q            +++  L +  + LHVA+ SR +E+ YL+ +++ L P + P     T  +    L++E  +G+V LP MD VA PD +N  + + +  S     + +  S+ VP L R+     +K   L+   K I     +  L+ F+ ++K   AV  +   L ++    ++L PD+ +  K  + +++++      L +    +     +   I  +IA+G Y  V +L+      E Y+ ++C
Sbjct:  135 SISEVLELVLENFVYPWYRDITDDEACVDELRQTIRFFAAVLAHRAQRVDVPSVVMDKMMKAAMKHIEIIAKAQQKVRNTDG----LEQAALAEYGADLHVALRSRKDELLYLRKLTELLFPYVMPP--KATDCRSLALLIREVMTGSVFLPIMDFVADPDTVNHMVLIFIDDSP-PEPVTDPPSTLVPFLERFADPRTKKSSVLKLDLKEIR--EQQDLLFRFMSFLKEEGAVHVLQFCLTVEEFNDRILCPDLSDDEKQRLHEEVKKIYETYCLEESIDKISFDPFIIEEI-HSIAEGPYTGVVKLQTMRCLFEAYEHVLC 447
[Close]
BLAST of Sorting nexin-14 vs. Ensembl Zebrafish
Match: snx14 (sorting nexin 14 [Source:NCBI gene;Acc:555970])

HSP 1 Score: 66.6254 bits (161), Expect = 1.905e-11
Identity = 60/185 (32.43%), Postives = 89/185 (48.11%), Query Frame = 3 
Query: 1644 KQKEFSMTKFGLSIKQVFTANSDDSLNL-----ISGDLDIDNP------DGSEWLSNSFGDLVDLPDLSYLRVKIPSISQPYVTNKKKGELYFSVYTYKVDSDKLLYK-----VHRKYGEFYVLEQKLLEFHGTIERA-LPPKRPWDNKNLDFLEKCKLEFETYLMYLVNRTFLRNSELLHRFLT 2147
            + + F +++ G  IK VF +++ +   L     I G+ D          D S    ++ G    L +LS   + IP +       KK+    F +   + D   + ++     V+RKY EFYVLE KL EFHG  + A LP KR    KN +FL   + EFE YL  L++   L NS+LL  FL+
Sbjct:   66 RGESFGISRIGSKIKGVFKSSTMEGAMLPQYAMIEGEDDTVEEAVMVFEDDSPGPMDAVGTPGTLRNLSAWTISIPYVDFYDDEVKKERIPVFCIDVERNDRKNVGHETESWSVYRKYVEFYVLESKLTEFHGPFQDAQLPSKRIIGPKNYEFLSSKRGEFEEYLQKLLHHPELSNSQLLADFLS 250
[Close]
BLAST of Sorting nexin-14 vs. Ensembl Zebrafish
Match: snx13 (sorting nexin 13 [Source:ZFIN;Acc:ZDB-GENE-050306-12])

HSP 1 Score: 51.9878 bits (123), Expect = 3.919e-6
Identity = 55/244 (22.54%), Postives = 110/244 (45.08%), Query Frame = 3 
Query:  303 LEEIFDIIIANYINSWYLGFSNNEDFIVEIKYFFHTLCAEILLRFSKISIPELVSQKFLPACINHLDICYTIQXXXXXXX---------XXLTPVQEILLQKMRSHLH-VAMISRSEEVAYLKSISKFLIPLITPDYFSRTKNKISDHLLQECFSGTVLLPAMDSVASPDLINKFIYLLLTPSTISTALCNTQSSYVPILHRYQTAWMEKLKRLEEHPKGIECLRNEKHLYHFLQYIKSVEAVS 1004
            L+++    + +YI  WY   S++E F++EI+        E   R  ++      + + +     HL +    Q   NE             L    E+ ++  R     V  +SR +E  YL+ + + L+ L+ P     +KN    + L+E  +  VLLP ++ ++ PD IN+F+  ++  S+     CN + +++ IL            +L + P  +E ++++  +   LQY++S++  S
Sbjct:  104 LQQVIQFALRDYIQYWYYTLSDDETFLLEIRLTVQNALVEFSTRSKEVDWQPYFTTRLVDDFATHLRVFRKAQEKLNEKEDPKQRDDPDELLDSFFEVEVEMERKICRDVVCMSRKDEEGYLRDLCEVLLYLLLPPGDFHSKN--MRYFLREVLARGVLLPLINQLSDPDYINQFVIWMIRDSS-----CNYE-AFLNIL------------KLTDEPSELEAVKDK--VLEELQYLRSLDTGS 325
[Close]
BLAST of Sorting nexin-14 vs. Ensembl Xenopus
Match: mettl2b (methyltransferase like 2B [Source:Xenbase;Acc:XB-GENE-947877])

HSP 1 Score: 156.377 bits (394), Expect = 3.356e-38
Identity = 120/344 (34.88%), Postives = 174/344 (50.58%), Query Frame = 3 
Query: 1929 YKVHRKYGEFYVLEQKLLEFHGTIERA-LPPKRPWDNKNLDFLEKCKLEFETYLMYLVNRTFLRNSELLHRFLTR---PTEFSFNSLIDINLGKFVKSMPMIFTKEKGQFLDQFLYNFHISCEASSQAKSNSNNDPYSSLSNSVSDPGSKSLFDARLHTRMYWNNAE----LNTIKSENFMKDICSFSTRYIFYYFDSLCFFFEIITNKLAYSHFLLNFFYRIRSILVDVFQTYVKGVITRGFEKLCHEKLAVEIIHVLRDAALLSGLN-RTISEKQERRNEALTSLYQLLPGWLSIVLSDDQIKTLYSNIDRIFDFLQQPKLNKQLSYVLFDILLLELFPELT 2933
            + V+RKY EFYVLE KL EFHGT   A LP KR    KN +FL   + EF+ YL  L+    L NS+LL  FL+     T+F    L D+NLGK +KS+P    KEKGQ L+ F+ NF  SCE+     S     P  ++ +  S+  +K LF+      +Y NN+     +    ++N+  ++ +    Y     D L +   ++ +   + H LL      R +     +TY    +    E+L  E   V +I +LRDA        R++  KQ+R       + + +P  +   + D+     Y  I  +FD LQQP LNKQLSYVL DI++ ELFPEL+
Sbjct:  603 WSVYRKYIEFYVLESKLTEFHGTFPDAQLPSKRIIGPKNYEFLMSKREEFQEYLQNLLQHPELSNSQLLADFLSPNSLETQFHDKILPDVNLGKMIKSVPGKLIKEKGQHLELFIMNFINSCESPKPKPSR----PELTILSPTSE-NNKKLFND-----LYKNNSNRSENIERKHNQNYFMEVMTIEGAY-----DYLMYVGRVVFHIPDWFHHLL---MGGRILFKHTLETYTNSYLNYKLEQLFQEHRLVSLITLLRDAIFCETTEPRSLQLKQQRAKFTFEEMMRYIPDLIGKCIGDE---AKYEGIRLLFDGLQQPVLNKQLSYVLLDIVIQELFPELS 925

HSP 2 Score: 114.005 bits (284), Expect = 4.333e-25
Identity = 81/346 (23.41%), Postives = 168/346 (48.55%), Query Frame = 3 
Query:  300 ALEEIFDIIIANYINSWYLGFSNNEDFIVEIKYFFHTLCAEILLRFSKISIPELVSQKFLPACINHLDICYTIQXXXXXXXXXLTPVQEILLQKMRSHLHVAMISRSEEVAYLKSISKFLIPLITPDYFSRTKNKISDHLLQECFSGTVLLPAMDSVASPDLINKFIYLLLTPSTISTALCNTQSSYVPILHRYQTAWMEKLKRLEEHPKGIECLRNEKH-LYHFLQYIKSVEAVSAVNIYLEMDAIILKLLSPDMDESTKIHIFQDIERFENLIHLSDGKSNLIISSDLRRRIKEAIADGYQNVDRLRNCEIWMENYQLICQHNQSLYLSQYFES-EFFLSTIYG 1331
            +L E+F++++ N++  WY   + +E F+ E++       + ++ R  K+ IP +++QK L A + H++I    +     +      +Q+  L++    LHVA+ SR +E+ YL+ +++ L P I P     T ++    LL+E  SG+V LP+MD +A PD +NK + + +  S    A   T SS +P L ++     +    L+     ++ +R E+  L+ F+ ++K   AV  +   L ++    K+L P++ +     + +++ +      L +    +     +   IK+     Y+ V +L+      E Y+ +    ++++   +  S E+F   + G
Sbjct:  135 SLSEVFELVLENFVYPWYRDITEDESFVDEMRLSLRFFASVLVRRIQKVDIPSVITQKLLKAAMKHIEIIAKARQKVKNSEY----LQQAALEEYGPDLHVALRSRRDELLYLRKLTELLFPFILPP--KSTDSRPLTLLLREILSGSVFLPSMDFLADPDTVNKLLLIFMDDSPPEQATEPT-SSLIPFLQKFAEPRNKNPSVLKME---LQEIRKEQDLLFRFMNFLKQEGAVHVLQFCLTVEEFNDKILRPEISDDELQALHKEVLKIYKTYCLEESIDKIRFDPFIVEEIKKIAEGPYKEVVKLQTMCCLFEAYEHVLSLLENVFTPMFCHSDEYFRQLLEG 470
[Close]
BLAST of Sorting nexin-14 vs. Ensembl Xenopus
Match: mettl2b (methyltransferase like 2B [Source:Xenbase;Acc:XB-GENE-947877])

HSP 1 Score: 135.576 bits (340), Expect = 8.919e-32
Identity = 109/330 (33.03%), Postives = 161/330 (48.79%), Query Frame = 3 
Query: 1929 YKVHRKYGEFYVLEQKLLEFHGTIERA-LPPKRPWDNKNLDFLEKCKLEFETYLMYLVNRTFLRNSELLHRFLTR---PTEFSFNSLIDINLGKFVKSMPMIFTKEKGQFLDQFLYNFHISCEASSQAKSNSNNDPYSSLSNSVSDPGSKSLFDARLHTRMYWNNA----ELNTIKSENFMKDICSFSTRYIFYYFDSLCFFFEIITNKLAYSHFLLNFFYRIRSILVDVFQTYVKGVITRGFEKLCHEKLAVEIIHVLRDAALLSGLN-RTISEKQERRNEALTSLYQLLPGWLSIVLSDDQIKTLYSNIDRIFDFLQQPKLNKQLSYV 2891
            + V+RKY EFYVLE KL EFHGT   A LP KR    KN +FL   + EF+ YL  L+    L NS+LL  FL+     T+F    L D+NLGK +KS+P    KEKGQ L+ F+ NF  SCE+     S     P  ++ +  S+  +K LF+      +Y NN+     +    ++N+  ++ +    Y     D L +   ++ +   + H LL      R +     +TY    +    E+L  E   V +I +LRDA        R++  KQ+R       + + +P  +   + D+     Y  I  +FD LQQP LNKQL Y+
Sbjct:  545 WSVYRKYIEFYVLESKLTEFHGTFPDAQLPSKRIIGPKNYEFLMSKREEFQEYLQNLLQHPELSNSQLLADFLSPNSLETQFHDKILPDVNLGKMIKSVPGKLIKEKGQHLELFIMNFINSCESPKPKPSR----PELTILSPTSE-NNKKLFND-----LYKNNSNRSENIERKHNQNYFMEVMTIEGAY-----DYLMYVGRVVFHIPDWFHHLL---MGGRILFKHTLETYTNSYLNYKLEQLFQEHRLVSLITLLRDAIFCETTEPRSLQLKQQRAKFTFEEMMRYIPDLIGKCIGDE---AKYEGIRLLFDGLQQPVLNKQLLYI 853

HSP 2 Score: 98.9821 bits (245), Expect = 2.146e-20
Identity = 78/346 (22.54%), Postives = 163/346 (47.11%), Query Frame = 3 
Query:  300 ALEEIFDIIIANYINSWYLGFSNNEDFIVEIKYFFHTLCAEILLRFSKISIPELVSQKFLPACINHLDICYTIQXXXXXXXXXLTPVQEILLQKMRSHLHVAMISRSEEVAYLKSISKFLIPLITPDYFSRTKNKISDHLLQECFSGTVLLPAMDSVASPDLINKFIYLLLTPSTISTALCNTQSSYVPILHRYQTAWMEKLKRLEEHPKGIECLRNEKH-LYHFLQYIKSVEAVSAVNIYLEMDAIILKLLSPDMDESTKIHIFQDIERFENLIHLSDGKSNLIISSDLRRRIKEAIADGYQNVDRLRNCEIWMENYQLICQHNQSLYLSQYFES-EFFLSTIYG 1331
            +L E+F++++ N++  WY   + +E F+ E++       + ++ R  K+ IP +++QK L A + H++I    +     +      +Q+  L++    LHVA+ SR +E+ YL+ +++ L P I P     T ++    LL+E  SG+V LP+MD +A P +  K        +T  T      SS +P L ++     +    L+     ++ +R E+  L+ F+ ++K   AV  +   L ++    K+L P++ +     + +++ +      L +    +     +   IK+     Y+ V +L+      E Y+ +    ++++   +  S E+F   + G
Sbjct:   83 SLSEVFELVLENFVYPWYRDITEDESFVDEMRLSLRFFASVLVRRIQKVDIPSVITQKLLKAAMKHIEIIAKARQKVKNSEY----LQQAALEEYGPDLHVALRSRRDELLYLRKLTELLFPFILPP--KSTDSRPLTLLLREILSGSVFLPSMDFLADP-VRQKLSLFQPEQATEPT------SSLIPFLQKFAEPRNKNPSVLKME---LQEIRKEQDLLFRFMNFLKQEGAVHVLQFCLTVEEFNDKILRPEISDDELQALHKEVLKIYKTYCLEESIDKIRFDPFIVEEIKKIAEGPYKEVVKLQTMCCLFEAYEHVLSLLENVFTPMFCHSDEYFRQLLEG 412
[Close]
BLAST of Sorting nexin-14 vs. Ensembl Xenopus
Match: mettl2b (methyltransferase like 2B [Source:Xenbase;Acc:XB-GENE-947877])

HSP 1 Score: 132.109 bits (331), Expect = 1.133e-30
Identity = 107/327 (32.72%), Postives = 159/327 (48.62%), Query Frame = 3 
Query: 1929 YKVHRKYGEFYVLEQKLLEFHGTIERA-LPPKRPWDNKNLDFLEKCKLEFETYLMYLVNRTFLRNSELLHRFLTR---PTEFSFNSLIDINLGKFVKSMPMIFTKEKGQFLDQFLYNFHISCEASSQAKSNSNNDPYSSLSNSVSDPGSKSLFDARLHTRMYWNNA----ELNTIKSENFMKDICSFSTRYIFYYFDSLCFFFEIITNKLAYSHFLLNFFYRIRSILVDVFQTYVKGVITRGFEKLCHEKLAVEIIHVLRDAALLSGLN-RTISEKQERRNEALTSLYQLLPGWLSIVLSDDQIKTLYSNIDRIFDFLQQPKLNKQL 2882
            + V+RKY EFYVLE KL EFHGT   A LP KR    KN +FL   + EF+ YL  L+    L NS+LL  FL+     T+F    L D+NLGK +KS+P    KEKGQ L+ F+ NF  SCE+     S     P  ++ +  S+  +K LF+      +Y NN+     +    ++N+  ++ +    Y     D L +   ++ +   + H LL      R +     +TY    +    E+L  E   V +I +LRDA        R++  KQ+R       + + +P  +   + D+     Y  I  +FD LQQP LNKQ+
Sbjct:  578 WSVYRKYIEFYVLESKLTEFHGTFPDAQLPSKRIIGPKNYEFLMSKREEFQEYLQNLLQHPELSNSQLLADFLSPNSLETQFHDKILPDVNLGKMIKSVPGKLIKEKGQHLELFIMNFINSCESPKPKPSR----PELTILSPTSE-NNKKLFND-----LYKNNSNRSENIERKHNQNYFMEVMTIEGAY-----DYLMYVGRVVFHIPDWFHHLL---MGGRILFKHTLETYTNSYLNYKLEQLFQEHRLVSLITLLRDAIFCETTEPRSLQLKQQRAKFTFEEMMRYIPDLIGKCIGDE---AKYEGIRLLFDGLQQPVLNKQV 883

HSP 2 Score: 115.161 bits (287), Expect = 1.948e-25
Identity = 81/346 (23.41%), Postives = 168/346 (48.55%), Query Frame = 3 
Query:  300 ALEEIFDIIIANYINSWYLGFSNNEDFIVEIKYFFHTLCAEILLRFSKISIPELVSQKFLPACINHLDICYTIQXXXXXXXXXLTPVQEILLQKMRSHLHVAMISRSEEVAYLKSISKFLIPLITPDYFSRTKNKISDHLLQECFSGTVLLPAMDSVASPDLINKFIYLLLTPSTISTALCNTQSSYVPILHRYQTAWMEKLKRLEEHPKGIECLRNEKH-LYHFLQYIKSVEAVSAVNIYLEMDAIILKLLSPDMDESTKIHIFQDIERFENLIHLSDGKSNLIISSDLRRRIKEAIADGYQNVDRLRNCEIWMENYQLICQHNQSLYLSQYFES-EFFLSTIYG 1331
            +L E+F++++ N++  WY   + +E F+ E++       + ++ R  K+ IP +++QK L A + H++I    +     +      +Q+  L++    LHVA+ SR +E+ YL+ +++ L P I P     T ++    LL+E  SG+V LP+MD +A PD +NK + + +  S    A   T SS +P L ++     +    L+     ++ +R E+  L+ F+ ++K   AV  +   L ++    K+L P++ +     + +++ +      L +    +     +   IK+     Y+ V +L+      E Y+ +    ++++   +  S E+F   + G
Sbjct:  110 SLSEVFELVLENFVYPWYRDITEDESFVDEMRLSLRFFASVLVRRIQKVDIPSVITQKLLKAAMKHIEIIAKARQKVKNSEY----LQQAALEEYGPDLHVALRSRRDELLYLRKLTELLFPFILPP--KSTDSRPLTLLLREILSGSVFLPSMDFLADPDTVNKLLLIFMDDSPPEQATEPT-SSLIPFLQKFAEPRNKNPSVLKME---LQEIRKEQDLLFRFMNFLKQEGAVHVLQFCLTVEEFNDKILRPEISDDELQALHKEVLKIYKTYCLEESIDKIRFDPFIVEEIKKIAEGPYKEVVKLQTMCCLFEAYEHVLSLLENVFTPMFCHSDEYFRQLLEG 445
[Close]
BLAST of Sorting nexin-14 vs. Ensembl Xenopus
Match: mettl2b (methyltransferase like 2B [Source:Xenbase;Acc:XB-GENE-947877])

HSP 1 Score: 131.339 bits (329), Expect = 2.355e-30
Identity = 107/326 (32.82%), Postives = 158/326 (48.47%), Query Frame = 3 
Query: 1929 YKVHRKYGEFYVLEQKLLEFHGTIERA-LPPKRPWDNKNLDFLEKCKLEFETYLMYLVNRTFLRNSELLHRFLTR---PTEFSFNSLIDINLGKFVKSMPMIFTKEKGQFLDQFLYNFHISCEASSQAKSNSNNDPYSSLSNSVSDPGSKSLFDARLHTRMYWNNA----ELNTIKSENFMKDICSFSTRYIFYYFDSLCFFFEIITNKLAYSHFLLNFFYRIRSILVDVFQTYVKGVITRGFEKLCHEKLAVEIIHVLRDAALLSGLN-RTISEKQERRNEALTSLYQLLPGWLSIVLSDDQIKTLYSNIDRIFDFLQQPKLNKQ 2879
            + V+RKY EFYVLE KL EFHGT   A LP KR    KN +FL   + EF+ YL  L+    L NS+LL  FL+     T+F    L D+NLGK +KS+P    KEKGQ L+ F+ NF  SCE+     S     P  ++ +  S+  +K LF+      +Y NN+     +    ++N+  ++ +    Y     D L +   ++ +   + H LL      R +     +TY    +    E+L  E   V +I +LRDA        R++  KQ+R       + + +P  +   + D+     Y  I  +FD LQQP LNKQ
Sbjct:  603 WSVYRKYIEFYVLESKLTEFHGTFPDAQLPSKRIIGPKNYEFLMSKREEFQEYLQNLLQHPELSNSQLLADFLSPNSLETQFHDKILPDVNLGKMIKSVPGKLIKEKGQHLELFIMNFINSCESPKPKPSR----PELTILSPTSE-NNKKLFND-----LYKNNSNRSENIERKHNQNYFMEVMTIEGAY-----DYLMYVGRVVFHIPDWFHHLL---MGGRILFKHTLETYTNSYLNYKLEQLFQEHRLVSLITLLRDAIFCETTEPRSLQLKQQRAKFTFEEMMRYIPDLIGKCIGDE---AKYEGIRLLFDGLQQPVLNKQ 907

HSP 2 Score: 113.62 bits (283), Expect = 5.782e-25
Identity = 81/346 (23.41%), Postives = 168/346 (48.55%), Query Frame = 3 
Query:  300 ALEEIFDIIIANYINSWYLGFSNNEDFIVEIKYFFHTLCAEILLRFSKISIPELVSQKFLPACINHLDICYTIQXXXXXXXXXLTPVQEILLQKMRSHLHVAMISRSEEVAYLKSISKFLIPLITPDYFSRTKNKISDHLLQECFSGTVLLPAMDSVASPDLINKFIYLLLTPSTISTALCNTQSSYVPILHRYQTAWMEKLKRLEEHPKGIECLRNEKH-LYHFLQYIKSVEAVSAVNIYLEMDAIILKLLSPDMDESTKIHIFQDIERFENLIHLSDGKSNLIISSDLRRRIKEAIADGYQNVDRLRNCEIWMENYQLICQHNQSLYLSQYFES-EFFLSTIYG 1331
            +L E+F++++ N++  WY   + +E F+ E++       + ++ R  K+ IP +++QK L A + H++I    +     +      +Q+  L++    LHVA+ SR +E+ YL+ +++ L P I P     T ++    LL+E  SG+V LP+MD +A PD +NK + + +  S    A   T SS +P L ++     +    L+     ++ +R E+  L+ F+ ++K   AV  +   L ++    K+L P++ +     + +++ +      L +    +     +   IK+     Y+ V +L+      E Y+ +    ++++   +  S E+F   + G
Sbjct:  135 SLSEVFELVLENFVYPWYRDITEDESFVDEMRLSLRFFASVLVRRIQKVDIPSVITQKLLKAAMKHIEIIAKARQKVKNSEY----LQQAALEEYGPDLHVALRSRRDELLYLRKLTELLFPFILPP--KSTDSRPLTLLLREILSGSVFLPSMDFLADPDTVNKLLLIFMDDSPPEQATEPT-SSLIPFLQKFAEPRNKNPSVLKME---LQEIRKEQDLLFRFMNFLKQEGAVHVLQFCLTVEEFNDKILRPEISDDELQALHKEVLKIYKTYCLEESIDKIRFDPFIVEEIKKIAEGPYKEVVKLQTMCCLFEAYEHVLSLLENVFTPMFCHSDEYFRQLLEG 470
[Close]
BLAST of Sorting nexin-14 vs. Ensembl Xenopus
Match: mettl2b (methyltransferase like 2B [Source:Xenbase;Acc:XB-GENE-947877])

HSP 1 Score: 130.954 bits (328), Expect = 2.588e-30
Identity = 107/326 (32.82%), Postives = 158/326 (48.47%), Query Frame = 3 
Query: 1929 YKVHRKYGEFYVLEQKLLEFHGTIERA-LPPKRPWDNKNLDFLEKCKLEFETYLMYLVNRTFLRNSELLHRFLTR---PTEFSFNSLIDINLGKFVKSMPMIFTKEKGQFLDQFLYNFHISCEASSQAKSNSNNDPYSSLSNSVSDPGSKSLFDARLHTRMYWNNA----ELNTIKSENFMKDICSFSTRYIFYYFDSLCFFFEIITNKLAYSHFLLNFFYRIRSILVDVFQTYVKGVITRGFEKLCHEKLAVEIIHVLRDAALLSGLN-RTISEKQERRNEALTSLYQLLPGWLSIVLSDDQIKTLYSNIDRIFDFLQQPKLNKQ 2879
            + V+RKY EFYVLE KL EFHGT   A LP KR    KN +FL   + EF+ YL  L+    L NS+LL  FL+     T+F    L D+NLGK +KS+P    KEKGQ L+ F+ NF  SCE+     S     P  ++ +  S+  +K LF+      +Y NN+     +    ++N+  ++ +    Y     D L +   ++ +   + H LL      R +     +TY    +    E+L  E   V +I +LRDA        R++  KQ+R       + + +P  +   + D+     Y  I  +FD LQQP LNKQ
Sbjct:  606 WSVYRKYIEFYVLESKLTEFHGTFPDAQLPSKRIIGPKNYEFLMSKREEFQEYLQNLLQHPELSNSQLLADFLSPNSLETQFHDKILPDVNLGKMIKSVPGKLIKEKGQHLELFIMNFINSCESPKPKPSR----PELTILSPTSE-NNKKLFND-----LYKNNSNRSENIERKHNQNYFMEVMTIEGAY-----DYLMYVGRVVFHIPDWFHHLL---MGGRILFKHTLETYTNSYLNYKLEQLFQEHRLVSLITLLRDAIFCETTEPRSLQLKQQRAKFTFEEMMRYIPDLIGKCIGDE---AKYEGIRLLFDGLQQPVLNKQ 910

HSP 2 Score: 98.9821 bits (245), Expect = 2.263e-20
Identity = 78/346 (22.54%), Postives = 163/346 (47.11%), Query Frame = 3 
Query:  300 ALEEIFDIIIANYINSWYLGFSNNEDFIVEIKYFFHTLCAEILLRFSKISIPELVSQKFLPACINHLDICYTIQXXXXXXXXXLTPVQEILLQKMRSHLHVAMISRSEEVAYLKSISKFLIPLITPDYFSRTKNKISDHLLQECFSGTVLLPAMDSVASPDLINKFIYLLLTPSTISTALCNTQSSYVPILHRYQTAWMEKLKRLEEHPKGIECLRNEKH-LYHFLQYIKSVEAVSAVNIYLEMDAIILKLLSPDMDESTKIHIFQDIERFENLIHLSDGKSNLIISSDLRRRIKEAIADGYQNVDRLRNCEIWMENYQLICQHNQSLYLSQYFES-EFFLSTIYG 1331
            +L E+F++++ N++  WY   + +E F+ E++       + ++ R  K+ IP +++QK L A + H++I    +     +      +Q+  L++    LHVA+ SR +E+ YL+ +++ L P I P     T ++    LL+E  SG+V LP+MD +A P +  K        +T  T      SS +P L ++     +    L+     ++ +R E+  L+ F+ ++K   AV  +   L ++    K+L P++ +     + +++ +      L +    +     +   IK+     Y+ V +L+      E Y+ +    ++++   +  S E+F   + G
Sbjct:  137 SLSEVFELVLENFVYPWYRDITEDESFVDEMRLSLRFFASVLVRRIQKVDIPSVITQKLLKAAMKHIEIIAKARQKVKNSEY----LQQAALEEYGPDLHVALRSRRDELLYLRKLTELLFPFILPP--KSTDSRPLTLLLREILSGSVFLPSMDFLADP-VRQKLSLFQPEQATEPT------SSLIPFLQKFAEPRNKNPSVLKME---LQEIRKEQDLLFRFMNFLKQEGAVHVLQFCLTVEEFNDKILRPEISDDELQALHKEVLKIYKTYCLEESIDKIRFDPFIVEEIKKIAEGPYKEVVKLQTMCCLFEAYEHVLSLLENVFTPMFCHSDEYFRQLLEG 466
[Close]
BLAST of Sorting nexin-14 vs. Ensembl Mouse
Match: Snx14 (sorting nexin 14 [Source:MGI Symbol;Acc:MGI:2155664])

HSP 1 Score: 150.984 bits (380), Expect = 9.643e-37
Identity = 138/458 (30.13%), Postives = 218/458 (47.60%), Query Frame = 3 
Query: 1644 KQKEFSMTKFGLSIKQVFTANSDDSL-----NLISGDLDIDNPDGSEWLSNSFGDLVDLPD----LSYLRVKIPSI---SQPYVTNKKKGELYFSVYTYKVDSDKLL--------YKVHRKYGEFYVLEQKLLEFHGTIERA-LPPKRPWDNKNLDFLEKCKLEFETYLMYLVNRTFLRNSELLHRFLT---RPTEFSFNSLIDINLGKFVKSMPMIFTKEKGQFLDQFLYNFHISCEASSQAKSNSNNDPYSSLSNSVSDPGSKSLFDARLHTRMYWNNAEL--NTIK--SENFMKDICSFSTRYIFYYFDSLCFFFEIITNKLAYSHFLLNFFYRIRSILVDVFQTYVKGVITRGFEKLCHEKLAVEIIHVLRDAALLSGLN-RTISEKQERRNEALTSLYQLLPGWLSIVLSDDQIKTLYSNIDRIFDFLQQPKLNKQLSYVLFDILLLELFPEL 2930
            + + F +++ G  IK VF + + +        +  G+ D           +S  + V  P+    L+  ++ IP +     P    K+K E    V+   V+ +           + V+R+Y EFYVLE KL EFHGT   A LP KR    KN +FL+  + EF+ YL  LV    L NS+LL  FL+     T+F    L D+NLGK +KS+P    KEKGQ L+ F+ +F  SCE+     S     P  ++ +  S+  +K LF+      ++ NNA    NT +  ++N+  ++ +    Y     D L +   ++     + H LL      R +  +  + Y    +    E+L  E   V +I +LRDA        R++ +KQ+   +    +   +P  +   + ++   T Y +I  +FD LQQP LNKQL+YVL DI++ ELFPEL
Sbjct:  471 RGESFGISRIGSKIKGVFKSTTMEGAVLPNYGVAEGEDDFIEEGIVVMEDDSPVEAVSTPNTPRNLAAWKISIPYVDFFEDPSSERKEKKE-RIPVFCIDVERNDRRAVGHEPEHWSVYRRYLEFYVLESKLTEFHGTFPDAQLPSKRIIGPKNYEFLKSKREEFQEYLQKLVQHPELSNSQLLADFLSPNGGETQFLDKILPDVNLGKIIKSVPGKLMKEKGQHLEPFIMSFINSCESPKPKPSR----PELTILSPTSE-NNKKLFND-----LFKNNANRAENTERKQNQNYFMEVMTVDGVY-----DYLMYVGRVVFQVPDWLHHLL---MGTRILFKNTLEMYTDYYLQCKLEQLFQEHRLVSLITLLRDAIFCENTEPRSLQDKQKGAKQTFEEMMNYIPDLIVKCIGEE---TKYESIRLLFDGLQQPVLNKQLTYVLLDIVIQELFPEL 906

HSP 2 Score: 83.9593 bits (206), Expect = 7.680e-16
Identity = 65/300 (21.67%), Postives = 137/300 (45.67%), Query Frame = 3 
Query:  435 FSKISIPELVSQKFLPACINHLDICYTIQXXXXXXXXXLTPVQEILLQKMRSHLHVAMISRSEEVAYLKSISKFLIPLITPDYFSRTKNKISDHLLQECFSGTVLLPAMDSVASPDLINKFIYLLLTPSTISTALCNTQSSYVPILHRYQTAWMEKLKRLEEHPKGIECLRNEKHLYHFLQYIKSVEAVSAVNIYLEMDAIILKLLSPDMDESTKIHIFQDIERFENLIHLSDGKSNLIISSDLRRRIKEAIADGYQNVDRLRNCEIWMENYQLICQHNQSLYLSQYFES-EFFLSTIYG 1331
             S++ IP ++++K L A + H+++    +            +Q+  L++    LHVA+ SR +E+ YL+ +++ L P I P     T  +    L++E  SG+VLLP++D +A PD +N  + + +  S    A     S  VP L ++     +K   L+   K I     +  L+ F+ ++K   AV  +   L ++    ++L P++     + + +++++      L +    +     +   I+      Y +V +L+      E Y+ +    ++++   +  S E+F   + G
Sbjct:  164 LSEVDIPSIITKKLLKAAMKHIEVIVKARQKVKNTEY----LQQAALEEYGPELHVALRSRRDELQYLRKLTELLFPYILPP--KATDCRSLTLLIREILSGSVLLPSLDFLADPDTVNHLLIIFIDDSPPEKA-TEPASPLVPFLQKFAEPRNKKPSVLKLELKQIR--EQQDLLFRFMNFLKQEGAVHVLQFCLTVEEFNDRILRPELSNDEMLSLHEELQKIYKTYCLDESIDKIRFDPFIVEEIQRIAEGPYIDVVKLQTMRCLFEAYEHVLSLLENVFTPMFCHSDEYFRQLLRG 454
[Close]
BLAST of Sorting nexin-14 vs. Ensembl Mouse
Match: Snx14 (sorting nexin 14 [Source:MGI Symbol;Acc:MGI:2155664])

HSP 1 Score: 151.369 bits (381), Expect = 9.710e-37
Identity = 138/458 (30.13%), Postives = 218/458 (47.60%), Query Frame = 3 
Query: 1644 KQKEFSMTKFGLSIKQVFTANSDDSL-----NLISGDLDIDNPDGSEWLSNSFGDLVDLPD----LSYLRVKIPSI---SQPYVTNKKKGELYFSVYTYKVDSDKLL--------YKVHRKYGEFYVLEQKLLEFHGTIERA-LPPKRPWDNKNLDFLEKCKLEFETYLMYLVNRTFLRNSELLHRFLT---RPTEFSFNSLIDINLGKFVKSMPMIFTKEKGQFLDQFLYNFHISCEASSQAKSNSNNDPYSSLSNSVSDPGSKSLFDARLHTRMYWNNAEL--NTIK--SENFMKDICSFSTRYIFYYFDSLCFFFEIITNKLAYSHFLLNFFYRIRSILVDVFQTYVKGVITRGFEKLCHEKLAVEIIHVLRDAALLSGLN-RTISEKQERRNEALTSLYQLLPGWLSIVLSDDQIKTLYSNIDRIFDFLQQPKLNKQLSYVLFDILLLELFPEL 2930
            + + F +++ G  IK VF + + +        +  G+ D           +S  + V  P+    L+  ++ IP +     P    K+K E    V+   V+ +           + V+R+Y EFYVLE KL EFHGT   A LP KR    KN +FL+  + EF+ YL  LV    L NS+LL  FL+     T+F    L D+NLGK +KS+P    KEKGQ L+ F+ +F  SCE+     S     P  ++ +  S+  +K LF+      ++ NNA    NT +  ++N+  ++ +    Y     D L +   ++     + H LL      R +  +  + Y    +    E+L  E   V +I +LRDA        R++ +KQ+   +    +   +P  +   + ++   T Y +I  +FD LQQP LNKQL+YVL DI++ ELFPEL
Sbjct:  515 RGESFGISRIGSKIKGVFKSTTMEGAVLPNYGVAEGEDDFIEEGIVVMEDDSPVEAVSTPNTPRNLAAWKISIPYVDFFEDPSSERKEKKE-RIPVFCIDVERNDRRAVGHEPEHWSVYRRYLEFYVLESKLTEFHGTFPDAQLPSKRIIGPKNYEFLKSKREEFQEYLQKLVQHPELSNSQLLADFLSPNGGETQFLDKILPDVNLGKIIKSVPGKLMKEKGQHLEPFIMSFINSCESPKPKPSR----PELTILSPTSE-NNKKLFND-----LFKNNANRAENTERKQNQNYFMEVMTVDGVY-----DYLMYVGRVVFQVPDWLHHLL---MGTRILFKNTLEMYTDYYLQCKLEQLFQEHRLVSLITLLRDAIFCENTEPRSLQDKQKGAKQTFEEMMNYIPDLIVKCIGEE---TKYESIRLLFDGLQQPVLNKQLTYVLLDIVIQELFPEL 950

HSP 2 Score: 108.612 bits (270), Expect = 1.713e-23
Identity = 74/345 (21.45%), Postives = 162/345 (46.96%), Query Frame = 3 
Query:  300 ALEEIFDIIIANYINSWYLGFSNNEDFIVEIKYFFHTLCAEILLRFSKISIPELVSQKFLPACINHLDICYTIQXXXXXXXXXLTPVQEILLQKMRSHLHVAMISRSEEVAYLKSISKFLIPLITPDYFSRTKNKISDHLLQECFSGTVLLPAMDSVASPDLINKFIYLLLTPSTISTALCNTQSSYVPILHRYQTAWMEKLKRLEEHPKGIECLRNEKHLYHFLQYIKSVEAVSAVNIYLEMDAIILKLLSPDMDESTKIHIFQDIERFENLIHLSDGKSNLIISSDLRRRIKEAIADGYQNVDRLRNCEIWMENYQLICQHNQSLYLSQYFES-EFFLSTIYG 1331
            +L E+ ++++ N++  WY   +++E F+ E++       + ++ R  K+ IP ++++K L A + H+++    +            +Q+  L++    LHVA+ SR +E+ YL+ +++ L P I P     T  +    L++E  SG+VLLP++D +A PD +N  + + +  S    A     S  VP L ++     +K   L+   K I     +  L+ F+ ++K   AV  +   L ++    ++L P++     + + +++++      L +    +     +   I+      Y +V +L+      E Y+ +    ++++   +  S E+F   + G
Sbjct:  163 SLSEVLELVLENFVYPWYRDVTDDESFVDELRITLRFFASVLVRRIHKVDIPSIITKKLLKAAMKHIEVIVKARQKVKNTEY----LQQAALEEYGPELHVALRSRRDELQYLRKLTELLFPYILPP--KATDCRSLTLLIREILSGSVLLPSLDFLADPDTVNHLLIIFIDDSPPEKA-TEPASPLVPFLQKFAEPRNKKPSVLKLELKQIR--EQQDLLFRFMNFLKQEGAVHVLQFCLTVEEFNDRILRPELSNDEMLSLHEELQKIYKTYCLDESIDKIRFDPFIVEEIQRIAEGPYIDVVKLQTMRCLFEAYEHVLSLLENVFTPMFCHSDEYFRQLLRG 498
[Close]
BLAST of Sorting nexin-14 vs. Ensembl Mouse
Match: Snx14 (sorting nexin 14 [Source:MGI Symbol;Acc:MGI:2155664])

HSP 1 Score: 150.984 bits (380), Expect = 1.146e-36
Identity = 118/343 (34.40%), Postives = 177/343 (51.60%), Query Frame = 3 
Query: 1929 YKVHRKYGEFYVLEQKLLEFHGTIERA-LPPKRPWDNKNLDFLEKCKLEFETYLMYLVNRTFLRNSELLHRFLT---RPTEFSFNSLIDINLGKFVKSMPMIFTKEKGQFLDQFLYNFHISCEASSQAKSNSNNDPYSSLSNSVSDPGSKSLFDARLHTRMYWNNAEL--NTIK--SENFMKDICSFSTRYIFYYFDSLCFFFEIITNKLAYSHFLLNFFYRIRSILVDVFQTYVKGVITRGFEKLCHEKLAVEIIHVLRDAALLSGLN-RTISEKQERRNEALTSLYQLLPGWLSIVLSDDQIKTLYSNIDRIFDFLQQPKLNKQLSYVLFDILLLELFPEL 2930
            + V+R+Y EFYVLE KL EFHGT   A LP KR    KN +FL+  + EF+ YL  LV    L NS+LL  FL+     T+F    L D+NLGK +KS+P    KEKGQ L+ F+ +F  SCE+     S     P  ++ +  S+  +K LF+      ++ NNA    NT +  ++N+  ++ +    Y     D L +   ++     + H LL      R +  +  + Y    +    E+L  E   V +I +LRDA        R++ +KQ+   +    +   +P  +   + ++   T Y +I  +FD LQQP LNKQL+YVL DI++ ELFPEL
Sbjct:  638 WSVYRRYLEFYVLESKLTEFHGTFPDAQLPSKRIIGPKNYEFLKSKREEFQEYLQKLVQHPELSNSQLLADFLSPNGGETQFLDKILPDVNLGKIIKSVPGKLMKEKGQHLEPFIMSFINSCESPKPKPSR----PELTILSPTSE-NNKKLFND-----LFKNNANRAENTERKQNQNYFMEVMTVDGVY-----DYLMYVGRVVFQVPDWLHHLL---MGTRILFKNTLEMYTDYYLQCKLEQLFQEHRLVSLITLLRDAIFCENTEPRSLQDKQKGAKQTFEEMMNYIPDLIVKCIGEE---TKYESIRLLFDGLQQPVLNKQLTYVLLDIVIQELFPEL 959

HSP 2 Score: 108.612 bits (270), Expect = 1.613e-23
Identity = 74/345 (21.45%), Postives = 162/345 (46.96%), Query Frame = 3 
Query:  300 ALEEIFDIIIANYINSWYLGFSNNEDFIVEIKYFFHTLCAEILLRFSKISIPELVSQKFLPACINHLDICYTIQXXXXXXXXXLTPVQEILLQKMRSHLHVAMISRSEEVAYLKSISKFLIPLITPDYFSRTKNKISDHLLQECFSGTVLLPAMDSVASPDLINKFIYLLLTPSTISTALCNTQSSYVPILHRYQTAWMEKLKRLEEHPKGIECLRNEKHLYHFLQYIKSVEAVSAVNIYLEMDAIILKLLSPDMDESTKIHIFQDIERFENLIHLSDGKSNLIISSDLRRRIKEAIADGYQNVDRLRNCEIWMENYQLICQHNQSLYLSQYFES-EFFLSTIYG 1331
            +L E+ ++++ N++  WY   +++E F+ E++       + ++ R  K+ IP ++++K L A + H+++    +            +Q+  L++    LHVA+ SR +E+ YL+ +++ L P I P     T  +    L++E  SG+VLLP++D +A PD +N  + + +  S    A     S  VP L ++     +K   L+   K I     +  L+ F+ ++K   AV  +   L ++    ++L P++     + + +++++      L +    +     +   I+      Y +V +L+      E Y+ +    ++++   +  S E+F   + G
Sbjct:  163 SLSEVLELVLENFVYPWYRDVTDDESFVDELRITLRFFASVLVRRIHKVDIPSIITKKLLKAAMKHIEVIVKARQKVKNTEY----LQQAALEEYGPELHVALRSRRDELQYLRKLTELLFPYILPP--KATDCRSLTLLIREILSGSVLLPSLDFLADPDTVNHLLIIFIDDSPPEKA-TEPASPLVPFLQKFAEPRNKKPSVLKLELKQIR--EQQDLLFRFMNFLKQEGAVHVLQFCLTVEEFNDRILRPELSNDEMLSLHEELQKIYKTYCLDESIDKIRFDPFIVEEIQRIAEGPYIDVVKLQTMRCLFEAYEHVLSLLENVFTPMFCHSDEYFRQLLRG 498
[Close]
BLAST of Sorting nexin-14 vs. Ensembl Mouse
Match: Snx14 (sorting nexin 14 [Source:MGI Symbol;Acc:MGI:2155664])

HSP 1 Score: 104.76 bits (260), Expect = 2.043e-22
Identity = 63/270 (23.33%), Postives = 135/270 (50.00%), Query Frame = 3 
Query:  300 ALEEIFDIIIANYINSWYLGFSNNEDFIVEIKYFFHTLCAEILLRFSKISIPELVSQKFLPACINHLDICYTIQXXXXXXXXXLTPVQEILLQKMRSHLHVAMISRSEEVAYLKSISKFLIPLITPDYFSRTKNKISDHLLQECFSGTVLLPAMDSVASPDLINKFIYLLLTPSTISTALCNTQSSYVPILHRYQTAWMEKLKRLEEHPKGIECLRNEKHLYHFLQYIKSVEAVSAVNIYLEMDAIILKLLSPDMDESTKIHIFQDIERF 1109
            +L E+ ++++ N++  WY   +++E F+ E++       + ++ R  K+ IP ++++K L A + H+++    +            +Q+  L++    LHVA+ SR +E+ YL+ +++ L P I P     T  +    L++E  SG+VLLP++D +A PD +N  + + +  S    A     S  VP L ++     +K   L+   K I     +  L+ F+ ++K   AV  +   L ++    ++L P++     + + +++++ 
Sbjct:  163 SLSEVLELVLENFVYPWYRDVTDDESFVDELRITLRFFASVLVRRIHKVDIPSIITKKLLKAAMKHIEVIVKARQKVKNTEY----LQQAALEEYGPELHVALRSRRDELQYLRKLTELLFPYILPP--KATDCRSLTLLIREILSGSVLLPSLDFLADPDTVNHLLIIFIDDSPPEKA-TEPASPLVPFLQKFAEPRNKKPSVLKLELKQIR--EQQDLLFRFMNFLKQEGAVHVLQFCLTVEEFNDRILRPELSNDEMLSLHEELQKI 423

HSP 2 Score: 85.8853 bits (211), Expect = 1.334e-16
Identity = 74/255 (29.02%), Postives = 123/255 (48.24%), Query Frame = 3 
Query: 2181 DINLGKFVKSMPMIFTKEKGQFLDQFLYNFHISCEASSQAKSNSNNDPYSSLSNSVSDPGSKSLFDARLHTRMYWNNAEL--NTIK--SENFMKDICSFSTRYIFYYFDSLCFFFEIITNKLAYSHFLLNFFYRIRSILVDVFQTYVKGVITRGFEKLCHEKLAVEIIHVLRDAALLSGLN-RTISEKQERRNEALTSLYQLLPGWLSIVLSDDQIKTLYSNIDRIFDFLQQPKLNKQLSYVLFDILLLELFPEL 2930
            +I   K +KS+P    KEKGQ L+ F+ +F  SCE+     S     P  ++ +  S+  +K LF+      ++ NNA    NT +  ++N+  ++ +    Y     D L +   ++     + H LL      R +  +  + Y    +    E+L  E   V +I +LRDA        R++ +KQ+   +    +   +P  +   + ++   T Y +I  +FD LQQP LNKQL+YVL DI++ ELFPEL
Sbjct:  445 EIQRRKIIKSVPGKLMKEKGQHLEPFIMSFINSCESPKPKPSR----PELTILSPTSE-NNKKLFND-----LFKNNANRAENTERKQNQNYFMEVMTVDGVY-----DYLMYVGRVVFQVPDWLHHLL---MGTRILFKNTLEMYTDYYLQCKLEQLFQEHRLVSLITLLRDAIFCENTEPRSLQDKQKGAKQTFEEMMNYIPDLIVKCIGEE---TKYESIRLLFDGLQQPVLNKQLTYVLLDIVIQELFPEL 678
[Close]
BLAST of Sorting nexin-14 vs. UniProt/SwissProt
Match: sp|Q5PNP1|SNX14_DANRE (Sorting nexin-14 OS=Danio rerio OX=7955 GN=snx14 PE=2 SV=3)

HSP 1 Score: 158.303 bits (399), Expect = 3.928e-38
Identity = 137/457 (29.98%), Postives = 216/457 (47.26%), Query Frame = 3 
Query: 1644 KQKEFSMTKFGLSIKQVFTANSDDSLNL-----ISGDLDIDNP------DGSEWLSNSFGDLVDLPDLSYLRVKIPSISQPYVTNKKKGELYFSVYTYKVDSDKLLYK-----VHRKYGEFYVLEQKLLEFHGTIERA-LPPKRPWDNKNLDFLEKCKLEFETYLMYLVNRTFLRNSELLHRFLT---RPTEFSFNSLIDINLGKFVKSMPMIFTKEKGQFLDQFLYNFHISCEASSQAKSNSNNDPYSSLSNSVSDPGSKSLFDARLHTRMYWNNAEL----NTIKSENFMKDICSFSTRYIFYYFDSLCFFFEIITNKLAYSHFLLNFFYRIRSILVDVFQTYVKGVITRGFEKLCHEKLAVEIIHVLRDAALL-SGLNRTISEKQERRNEALTSLYQLLPGWLSIVLSDDQIKTLYSNIDRIFDFLQQPKLNKQLSYVLFDILLLELFPELTDN 2939
            + + F +++ G  IK VF +++ +   L     I G+ D          D S    ++ G    L +LS   + IP +       KK+    F +   + D   + ++     V+RKY EFYVLE KL EFHG  + A LP KR    KN +FL   + EFE YL  L++   L NS+LL  FL+     ++F    L D+NLGK  KS+P    KEKGQ L+ F+ +F  SCE+    K   +    + LS +  +  +K LF+      +Y NNA L        ++N+  ++      Y     D + +   ++     + H LL+    +R +L    + YV        E++  E   V ++ +LRDA    S   R+  +KQ R  +    +   LP  +   + ++     Y  +  +F+ +QQP LNKQ++YVL DI + ELFPEL+ N
Sbjct:  487 RGESFGISRIGSKIKGVFKSSTMEGAMLPQYAMIEGEDDTVEEAVMVFEDDSPGPMDAVGTPGTLRNLSAWTISIPYVDFYDDEVKKERIPVFCIDVERNDRKNVGHETESWSVYRKYVEFYVLESKLTEFHGPFQDAQLPSKRIIGPKNYEFLSSKRGEFEEYLQKLLHHPELSNSQLLADFLSPFSMESQFRDKMLPDVNLGKIFKSVPGKLIKEKGQNLEPFIQSFFSSCES---PKPKPSRPELTILSPTAEN--NKKLFN-----ELYRNNANLPEGLEKKHNQNYFMELMEVDGAY-----DYMMYIGRVVFRMPDWLHHLLS---GVRILLKRTLEAYVGHYFQYKLEQIMEEHRLVSLVTLLRDAVFCESTEERSPEDKQRRAKQTFEEMMNYLPDIVGKCIGEE---AKYDGVKMLFNTIQQPLLNKQMTYVLLDIAIQELFPELSKN 922

HSP 2 Score: 103.99 bits (258), Expect = 3.399e-21
Identity = 73/323 (22.60%), Postives = 153/323 (47.37%), Query Frame = 3 
Query:  300 ALEEIFDIIIANYINSWYLGFSNNEDFIVEIKYFFHTLCAEILLRFSKISIPELVSQKFLPACINHLDICYTIQXXXXXXXXXLTPVQEILLQKMRSHLHVAMISRSEEVAYLKSISKFLIPLITPDYFSRTKNKISDHLLQECFSGTVLLPAMDSVASPDLINKFIYLLLTPSTISTALCNTQSSYVPILHRYQTAWMEKLKRLEEHPKGIECLRNEKHLYHFLQYIKSVEAVSAVNIYLEMDAIILKLLSPDMDESTKIHIFQDIERFENLIHLSDGKSNLIISSDLRRRIKEAIADG-YQNVDRLRNCEIWMENYQ-LIC 1262
            ++ E+ ++++ N++  WY   +++E  + E++       A +  R  ++ +P +V  K + A + H++I    Q            +++  L +  + LHVA+ SR +E+ YL+ +++ L P + P     T  +    L++E  +G+V LP MD VA PD +N  + + +  S     + +  S+ VP L R+     +K   L+   K I     +  L+ F+ ++K   AV  +   L ++    ++L PD+ +  K  + +++++      L +    +     +   I  +IA+G Y  V +L+      E Y+ ++C
Sbjct:  135 SISEVLELVLENFVYPWYRDITDDEACVDELRQTIRFFAAVLAHRAQRVDVPSVVMDKMMKAAMKHIEIIAKAQQKVRNTDG----LEQAALAEYGADLHVALRSRKDELLYLRKLTELLFPYVMPP--KATDCRSLALLIREVMTGSVFLPIMDFVADPDTVNHMVLIFIDDSP-PEPVTDPPSTLVPFLERFADPRTKKSSVLKLDLKEIR--EQQDLLFRFMSFLKEEGAVHVLQFCLTVEEFNDRILCPDLSDDEKQRLHEEVKKIYETYCLEESIDKISFDPFIIEEI-HSIAEGPYTGVVKLQTMRCLFEAYEHVLC 447
[Close]
BLAST of Sorting nexin-14 vs. UniProt/SwissProt
Match: sp|Q5R903|SNX14_PONAB (Sorting nexin-14 OS=Pongo abelii OX=9601 GN=SNX14 PE=2 SV=1)

HSP 1 Score: 152.91 bits (385), Expect = 1.870e-36
Identity = 139/458 (30.35%), Postives = 218/458 (47.60%), Query Frame = 3 
Query: 1644 KQKEFSMTKFGLSIKQVFTANSDDSL-----NLISGDLDIDNPDGSEWLSNSFGDLVDLPD----LSYLRVKIPSI---SQPYVTNKKKGELYFSVYTYKVDSDKLL--------YKVHRKYGEFYVLEQKLLEFHGTIERA-LPPKRPWDNKNLDFLEKCKLEFETYLMYLVNRTFLRNSELLHRFLT---RPTEFSFNSLIDINLGKFVKSMPMIFTKEKGQFLDQFLYNFHISCEASSQAKSNSNNDPYSSLSNSVSDPGSKSLFDARLHTRMYWNNAEL--NTIK--SENFMKDICSFSTRYIFYYFDSLCFFFEIITNKLAYSHFLLNFFYRIRSILVDVFQTYVKGVITRGFEKLCHEKLAVEIIHVLRDAALLSGLN-RTISEKQERRNEALTSLYQLLPGWLSIVLSDDQIKTLYSNIDRIFDFLQQPKLNKQLSYVLFDILLLELFPEL 2930
            + + F +++ G  IK VF + + +        +  G+ D           +S  + V  P+    L+  ++ IP +     P    K+K E    V+   V+ +           + V+R+Y EFYVLE KL EFHGT   A LP KR    KN +FL+  + EF+ YL  L+    L NS+LL  FL+     T+F    L D+NLGK +KS+P    KEKGQ L+ F+ NF  SCE+     S     P  ++ +  S+  +K LF+      ++ NNA    NT +  ++N+  ++ +    Y     D L +   ++     + H LL      R +  +  + Y    +    E+L  E   V +I +LRDA        R++ +KQ+   +    +   +P  L   + ++   T Y +I  +FD LQQP LNKQL+YVL DI++ ELFPEL
Sbjct:  445 RGESFGISRIGSKIKGVFKSTTMEGAMLPNYGVAEGEDDFIEEGIVVMEDDSPVEAVSTPNTPRNLAAWKISIPYVDFFEDPSSERKEKKE-RIPVFCIDVERNDRRAVGHEPEHWSVYRRYLEFYVLESKLTEFHGTFPDAQLPSKRIIGPKNYEFLKSKREEFQEYLQKLLQHPELSNSQLLADFLSPNGGETQFLDKILPDVNLGKIIKSVPGKLMKEKGQHLEPFIMNFINSCESPKPKPSR----PELTILSPTSE-NNKKLFND-----LFKNNANRAENTERKQNQNYFMEVMTVEGVY-----DYLMYVGRVVFQVPDWLHHLL---MGTRILFKNTLEMYTDYYLQCKLEQLFQEHRLVSLITLLRDAIFCENTEPRSLQDKQKGAKQTFEEMMNYIPDLLVKCIGEE---TKYESIRLLFDGLQQPVLNKQLTYVLLDIVIQELFPEL 880

HSP 2 Score: 107.457 bits (267), Expect = 2.781e-22
Identity = 73/345 (21.16%), Postives = 161/345 (46.67%), Query Frame = 3 
Query:  300 ALEEIFDIIIANYINSWYLGFSNNEDFIVEIKYFFHTLCAEILLRFSKISIPELVSQKFLPACINHLDICYTIQXXXXXXXXXLTPVQEILLQKMRSHLHVAMISRSEEVAYLKSISKFLIPLITPDYFSRTKNKISDHLLQECFSGTVLLPAMDSVASPDLINKFIYLLLTPSTISTALCNTQSSYVPILHRYQTAWMEKLKRLEEHPKGIECLRNEKHLYHFLQYIKSVEAVSAVNIYLEMDAIILKLLSPDMDESTKIHIFQDIERFENLIHLSDGKSNLIISSDLRRRIKEAIADGYQNVDRLRNCEIWMENYQLICQHNQSLYLSQYFES-EFFLSTIYG 1331
            +L E+ ++++ N++  WY   +++E F+ E++       + ++ R  K+ IP ++++K L A + H+++    +            +Q+  L++    LHVA+ SR +E+ YL+ +++ L P I P     T  +    L++E  SG+V LP++D +A PD +N  + + +  S    A     S  VP L ++     +K   L+   K I     +  L+ F+ ++K   AV  +   L ++    ++L P++     + + +++++      L +    +     +   I+      Y +V +L+      E Y+ +    ++++   +  S E+F   + G
Sbjct:   84 SLSEVLELVLENFVYPWYRDVTDDESFVDELRITLRFFASVLIRRIHKVDIPSIITKKLLKAAMKHIEVIVKARQKVKNTEF----LQQAALEEYGPELHVALRSRRDELHYLRKLTELLFPYILPP--KATDCRSLTLLIREILSGSVFLPSLDFLADPDTVNHLLIIFIDDSPPEKA-TEPASPLVPFLQKFAEPRNKKPSVLKLELKQIR--EQQDLLFRFMNFLKQEGAVHVLQFCLTVEEFNDRILRPELSNDEMLSLHEELQKIYKTYCLDESIDKIRFDPFIVEEIQRIAEGPYIDVVKLQTMRCLFEAYEHVLSLLENVFTPMFCHSDEYFRQLLRG 419
[Close]
BLAST of Sorting nexin-14 vs. UniProt/SwissProt
Match: sp|Q9Y5W7|SNX14_HUMAN (Sorting nexin-14 OS=Homo sapiens OX=9606 GN=SNX14 PE=1 SV=3)

HSP 1 Score: 151.369 bits (381), Expect = 6.528e-36
Identity = 138/458 (30.13%), Postives = 217/458 (47.38%), Query Frame = 3 
Query: 1644 KQKEFSMTKFGLSIKQVFTANSDDSL-----NLISGDLDIDNPDGSEWLSNSFGDLVDLPD----LSYLRVKIPSI---SQPYVTNKKKGELYFSVYTYKVDSDKLL--------YKVHRKYGEFYVLEQKLLEFHGTIERA-LPPKRPWDNKNLDFLEKCKLEFETYLMYLVNRTFLRNSELLHRFLT---RPTEFSFNSLIDINLGKFVKSMPMIFTKEKGQFLDQFLYNFHISCEASSQAKSNSNNDPYSSLSNSVSDPGSKSLFDARLHTRMYWNNAEL--NTIK--SENFMKDICSFSTRYIFYYFDSLCFFFEIITNKLAYSHFLLNFFYRIRSILVDVFQTYVKGVITRGFEKLCHEKLAVEIIHVLRDAALLSGLN-RTISEKQERRNEALTSLYQLLPGWLSIVLSDDQIKTLYSNIDRIFDFLQQPKLNKQLSYVLFDILLLELFPEL 2930
            + + F +++ G  IK VF + + +        +  G+ D           +S  + V  P+    L+  ++ IP +     P    K+K E    V+   V+ +           + V+R+Y EFYVLE KL EFHG    A LP KR    KN +FL+  + EF+ YL  L+    L NS+LL  FL+     T+F    L D+NLGK +KS+P    KEKGQ L+ F+ NF  SCE+     S     P  ++ +  S+  +K LF+      ++ NNA    NT +  ++N+  ++ +    Y     D L +   ++     + H LL      R +  +  + Y    +    E+L  E   V +I +LRDA        R++ +KQ+   +    +   +P  L   + ++   T Y +I  +FD LQQP LNKQL+YVL DI++ ELFPEL
Sbjct:  497 RGESFGISRIGSKIKGVFKSTTMEGAMLPNYGVAEGEDDFIEEGIVVMEDDSPVEAVSTPNTPRNLAAWKISIPYVDFFEDPSSERKEKKE-RIPVFCIDVERNDRRAVGHEPEHWSVYRRYLEFYVLESKLTEFHGAFPDAQLPSKRIIGPKNYEFLKSKREEFQEYLQKLLQHPELSNSQLLADFLSPNGGETQFLDKILPDVNLGKIIKSVPGKLMKEKGQHLEPFIMNFINSCESPKPKPSR----PELTILSPTSE-NNKKLFND-----LFKNNANRAENTERKQNQNYFMEVMTVEGVY-----DYLMYVGRVVFQVPDWLHHLL---MGTRILFKNTLEMYTDYYLQCKLEQLFQEHRLVSLITLLRDAIFCENTEPRSLQDKQKGAKQTFEEMMNYIPDLLVKCIGEE---TKYESIRLLFDGLQQPVLNKQLTYVLLDIVIQELFPEL 932

HSP 2 Score: 107.071 bits (266), Expect = 3.179e-22
Identity = 73/345 (21.16%), Postives = 161/345 (46.67%), Query Frame = 3 
Query:  300 ALEEIFDIIIANYINSWYLGFSNNEDFIVEIKYFFHTLCAEILLRFSKISIPELVSQKFLPACINHLDICYTIQXXXXXXXXXLTPVQEILLQKMRSHLHVAMISRSEEVAYLKSISKFLIPLITPDYFSRTKNKISDHLLQECFSGTVLLPAMDSVASPDLINKFIYLLLTPSTISTALCNTQSSYVPILHRYQTAWMEKLKRLEEHPKGIECLRNEKHLYHFLQYIKSVEAVSAVNIYLEMDAIILKLLSPDMDESTKIHIFQDIERFENLIHLSDGKSNLIISSDLRRRIKEAIADGYQNVDRLRNCEIWMENYQLICQHNQSLYLSQYFES-EFFLSTIYG 1331
            +L E+ ++++ N++  WY   +++E F+ E++       + ++ R  K+ IP ++++K L A + H+++    +            +Q+  L++    LHVA+ SR +E+ YL+ +++ L P I P     T  +    L++E  SG+V LP++D +A PD +N  + + +  S    A     S  VP L ++     +K   L+   K I     +  L+ F+ ++K   AV  +   L ++    ++L P++     + + +++++      L +    +     +   I+      Y +V +L+      E Y+ +    ++++   +  S E+F   + G
Sbjct:  136 SLSEVLELVLENFVYPWYRDVTDDESFVDELRITLRFFASVLIRRIHKVDIPSIITKKLLKAAMKHIEVIVKARQKVKNTEF----LQQAALEEYGPELHVALRSRRDELHYLRKLTELLFPYILPP--KATDCRSLTLLIREILSGSVFLPSLDFLADPDTVNHLLIIFIDDSPPEKA-TEPASPLVPFLQKFAEPRNKKPSVLKLELKQIR--EQQDLLFRFMNFLKQEGAVHVLQFCLTVEEFNDRILRPELSNDEMLSLHEELQKIYKTYCLDESIDKIRFDPFIVEEIQRIAEGPYIDVVKLQTMRCLFEAYEHVLSLLENVFTPMFCHSDEYFRQLLRG 471
[Close]
BLAST of Sorting nexin-14 vs. UniProt/SwissProt
Match: sp|Q8BHY8|SNX14_MOUSE (Sorting nexin-14 OS=Mus musculus OX=10090 GN=Snx14 PE=1 SV=2)

HSP 1 Score: 151.369 bits (381), Expect = 6.792e-36
Identity = 138/458 (30.13%), Postives = 218/458 (47.60%), Query Frame = 3 
Query: 1644 KQKEFSMTKFGLSIKQVFTANSDDSL-----NLISGDLDIDNPDGSEWLSNSFGDLVDLPD----LSYLRVKIPSI---SQPYVTNKKKGELYFSVYTYKVDSDKLL--------YKVHRKYGEFYVLEQKLLEFHGTIERA-LPPKRPWDNKNLDFLEKCKLEFETYLMYLVNRTFLRNSELLHRFLT---RPTEFSFNSLIDINLGKFVKSMPMIFTKEKGQFLDQFLYNFHISCEASSQAKSNSNNDPYSSLSNSVSDPGSKSLFDARLHTRMYWNNAEL--NTIK--SENFMKDICSFSTRYIFYYFDSLCFFFEIITNKLAYSHFLLNFFYRIRSILVDVFQTYVKGVITRGFEKLCHEKLAVEIIHVLRDAALLSGLN-RTISEKQERRNEALTSLYQLLPGWLSIVLSDDQIKTLYSNIDRIFDFLQQPKLNKQLSYVLFDILLLELFPEL 2930
            + + F +++ G  IK VF + + +        +  G+ D           +S  + V  P+    L+  ++ IP +     P    K+K E    V+   V+ +           + V+R+Y EFYVLE KL EFHGT   A LP KR    KN +FL+  + EF+ YL  LV    L NS+LL  FL+     T+F    L D+NLGK +KS+P    KEKGQ L+ F+ +F  SCE+     S     P  ++ +  S+  +K LF+      ++ NNA    NT +  ++N+  ++ +    Y     D L +   ++     + H LL      R +  +  + Y    +    E+L  E   V +I +LRDA        R++ +KQ+   +    +   +P  +   + ++   T Y +I  +FD LQQP LNKQL+YVL DI++ ELFPEL
Sbjct:  515 RGESFGISRIGSKIKGVFKSTTMEGAVLPNYGVAEGEDDFIEEGIVVMEDDSPVEAVSTPNTPRNLAAWKISIPYVDFFEDPSSERKEKKE-RIPVFCIDVERNDRRAVGHEPEHWSVYRRYLEFYVLESKLTEFHGTFPDAQLPSKRIIGPKNYEFLKSKREEFQEYLQKLVQHPELSNSQLLADFLSPNGGETQFLDKILPDVNLGKIIKSVPGKLMKEKGQHLEPFIMSFINSCESPKPKPSR----PELTILSPTSE-NNKKLFND-----LFKNNANRAENTERKQNQNYFMEVMTVDGVY-----DYLMYVGRVVFQVPDWLHHLL---MGTRILFKNTLEMYTDYYLQCKLEQLFQEHRLVSLITLLRDAIFCENTEPRSLQDKQKGAKQTFEEMMNYIPDLIVKCIGEE---TKYESIRLLFDGLQQPVLNKQLTYVLLDIVIQELFPEL 950

HSP 2 Score: 108.612 bits (270), Expect = 1.198e-22
Identity = 74/345 (21.45%), Postives = 162/345 (46.96%), Query Frame = 3 
Query:  300 ALEEIFDIIIANYINSWYLGFSNNEDFIVEIKYFFHTLCAEILLRFSKISIPELVSQKFLPACINHLDICYTIQXXXXXXXXXLTPVQEILLQKMRSHLHVAMISRSEEVAYLKSISKFLIPLITPDYFSRTKNKISDHLLQECFSGTVLLPAMDSVASPDLINKFIYLLLTPSTISTALCNTQSSYVPILHRYQTAWMEKLKRLEEHPKGIECLRNEKHLYHFLQYIKSVEAVSAVNIYLEMDAIILKLLSPDMDESTKIHIFQDIERFENLIHLSDGKSNLIISSDLRRRIKEAIADGYQNVDRLRNCEIWMENYQLICQHNQSLYLSQYFES-EFFLSTIYG 1331
            +L E+ ++++ N++  WY   +++E F+ E++       + ++ R  K+ IP ++++K L A + H+++    +            +Q+  L++    LHVA+ SR +E+ YL+ +++ L P I P     T  +    L++E  SG+VLLP++D +A PD +N  + + +  S    A     S  VP L ++     +K   L+   K I     +  L+ F+ ++K   AV  +   L ++    ++L P++     + + +++++      L +    +     +   I+      Y +V +L+      E Y+ +    ++++   +  S E+F   + G
Sbjct:  163 SLSEVLELVLENFVYPWYRDVTDDESFVDELRITLRFFASVLVRRIHKVDIPSIITKKLLKAAMKHIEVIVKARQKVKNTEY----LQQAALEEYGPELHVALRSRRDELQYLRKLTELLFPYILPP--KATDCRSLTLLIREILSGSVLLPSLDFLADPDTVNHLLIIFIDDSPPEKA-TEPASPLVPFLQKFAEPRNKKPSVLKLELKQIR--EQQDLLFRFMNFLKQEGAVHVLQFCLTVEEFNDRILRPELSNDEMLSLHEELQKIYKTYCLDESIDKIRFDPFIVEEIQRIAEGPYIDVVKLQTMRCLFEAYEHVLSLLENVFTPMFCHSDEYFRQLLRG 498
[Close]
BLAST of Sorting nexin-14 vs. TrEMBL
Match: A0A1A8IGD5 (Sorting nexin 14 OS=Nothobranchius kuhntae OX=321403 GN=SNX14 PE=4 SV=1)

HSP 1 Score: 249.21 bits (635), Expect = 2.976e-65
Identity = 224/914 (24.51%), Postives = 408/914 (44.64%), Query Frame = 3 
Query:  300 ALEEIFDIIIANYINSWYLGFSNNEDFIVEIKYFFHTLCAEILLRFSKISIPELVSQKFLPACINHLDICYTIQXXXXXXXXXLTPVQEILLQKMRSHLHVAMISRSEEVAYLKSISKFLIPLITPDYFSRTKNKISDHLLQECFSGTVLLPAMDSVASPDLINKFIYLLLTPSTISTALCNTQSSYVPILHRYQTAWMEKLKRLEEHPKGIECLRNEKHLYHFLQYIKSVEAVSAVNIYLEMDAIILKLLSPDMDESTKIHIFQDIERFENLIHLSDGKSNLIISSDLRRRIKEAIADGYQNVDRLRNCEIWMENYQLICQHNQSLYLSQYFES-EFFLSTIYGERLSDIDTSYECEWEDINVTGDSLNVVNPENLDNENLSRHESSPENFSFKKMSLDLFSFDFMSDRKSPIIEDQKSAFSTPDRVTXXXXXXXXXXXXXXXLSQIDKQKEFSMTKFGLSIKQVFTANSDD-----SLNLISGDLDIDNPDGSEWLSNSFGDLVDLP----DLSYLRVKIPSISQPYVTNKKKGELYFSVYTYKVDSDKLLYK-----VHRKYGEFYVLEQKLLEFHGTIERA-LPPKRPWDNKNLDFLEKCKLEFETYLMYLVNRTFLRNSELLHRFLT---RPTEFSFNSLIDINLGKFVKSMPMIFTKEKGQFLDQFLYNFHISCEASSQAKSNSNNDPYSSLSNSVSDPGSKSLFDARLHTRMYWNNAELNTIK----SENFMKDICSFSTRYIFYYFDSLCFFFEIITNKLAYSHFLLNFFYRIRSILVDVFQTYVKGVITRGFEKLCHEKLAVEIIHVLRDAALL-SGLNRTISEKQERRNEALTSLYQLLPGWLSIVLSDDQIKTLYSNIDRIFDFLQQPKLNKQLSYVLFDILLLELFPELTDNVVAQNQNEVP 2969
            +L EI ++++ N+++ WY   +++E F+ E++     + A ++ R  K+ +  +++QK L   + H++I    +            +Q+  L++    LHVA+ SR +E+ YL+++++ L P I P   +  ++     L++E  +G+V LP+MD +A PD +N  I + +  S    A     S+ VP LH+Y  +  +K   L+   K I     +  L+ F+ ++K   AV  +   L ++    ++L P++ +S K+ + +++++      L +    +     +   I+      Y +V +L+      E Y+ +    ++++   +  S E+F   + G      ++     W+            +PE+  +   +   SSP   SF  +     +F + S         Q    S+P   +                    + + F +++ G  IK VF + + +     S  L+ G+ D+          +S  + V  P    +LS   + IP I       K++    F +   + D   + ++     V+R+Y EFYVLE KL EFHG+   A LP KR    KN +FL   + +F+ YL  L+    L NS+LL  FL+     ++F    L D+NLGK +KS+P    KEKGQ L+ F+ +F  SCE+     S            ++  P S++  D +L   ++ NNA  + +     ++N+  ++ +    Y     D L +   ++ +   + H LL      R +  +  + Y    I     ++  E   V +I +LRD     S   R++ +KQ R       +   +P  LS  + ++     Y  +  +FD LQQP LNKQL+YVL DI + ELFPEL      +     P
Sbjct:  134 SLSEILELVLENFVHPWYREITDDEAFVDELRVTLRFIAAVLVRRTQKVDVASVITQKLLKVSMKHIEIISKARQKVKNAEC----LQQAALEEYGPDLHVALRSRRDELLYLRNLTEMLFPYILPPKAAECRSL--SLLIREVLAGSVFLPSMDYLADPDTVNHLILIFIDSSPPEDA-TEPASTLVPFLHKYSDSRNKKPSVLKLELKEIR--EQQDLLFRFMNFLKQEGAVHVLQFCLAVEEFNDRILCPELSDSEKMMLHEEVKKIYETYCLDESIDKIRFDPFIVEEIRNIAEGPYADVVKLQTMRCLFEAYEHVLSLLENVFTPMFCHSDEYFRQLLRGAESPTRNSKMSSFWD-----------WSPESPSSLCTASGSSSPA--SFNSLHAQFTNFPYGS---------QPHRHSSPKNTS-------------------KRGESFGISRIGSKIKGVFKSTTMEGAMLPSSGLVEGEDDMVEEAMMVLEDDSPMEAVSTPSTPRNLSAWSITIPYIDFYDDDAKRERIPVFCIDVERNDRKAVGHETEHWSVYRRYLEFYVLESKLTEFHGSFPDAQLPSKRIIGPKNYEFLTSKREDFQEYLQKLLQHPELSNSQLLADFLSPHSMESQFLDKMLPDVNLGKIIKSVPSKLIKEKGQHLEPFIQSFFNSCESPKPKPSRPEL--------TILSPTSEN--DKKLFNDLFKNNANRSEMTEKRHNQNYFMEMITVEGVY-----DYLMYVGRVVFHIPDWLHHLL---MGGRILFKNTLEAYTDNCIQFKLNQVVQEHRLVSLITLLRDTVFCESSSPRSVQDKQSRAKRTFEEMMSYIPDVLSKCIGEE---AKYEGVRLLFDGLQQPVLNKQLTYVLLDIAIQELFPELNKQAQKETSMMAP 976
[Close]
BLAST of Sorting nexin-14 vs. TrEMBL
Match: A0A1A8MLA2 (Sorting nexin 14 OS=Nothobranchius pienaari OX=704102 GN=SNX14 PE=4 SV=1)

HSP 1 Score: 248.825 bits (634), Expect = 4.597e-65
Identity = 223/914 (24.40%), Postives = 407/914 (44.53%), Query Frame = 3 
Query:  300 ALEEIFDIIIANYINSWYLGFSNNEDFIVEIKYFFHTLCAEILLRFSKISIPELVSQKFLPACINHLDICYTIQXXXXXXXXXLTPVQEILLQKMRSHLHVAMISRSEEVAYLKSISKFLIPLITPDYFSRTKNKISDHLLQECFSGTVLLPAMDSVASPDLINKFIYLLLTPSTISTALCNTQSSYVPILHRYQTAWMEKLKRLEEHPKGIECLRNEKHLYHFLQYIKSVEAVSAVNIYLEMDAIILKLLSPDMDESTKIHIFQDIERFENLIHLSDGKSNLIISSDLRRRIKEAIADGYQNVDRLRNCEIWMENYQLICQHNQSLYLSQYFES-EFFLSTIYGERLSDIDTSYECEWEDINVTGDSLNVVNPENLDNENLSRHESSPENFSFKKMSLDLFSFDFMSDRKSPIIEDQKSAFSTPDRVTXXXXXXXXXXXXXXXLSQIDKQKEFSMTKFGLSIKQVFTANSDD-----SLNLISGDLDIDNPDGSEWLSNSFGDLVDLP----DLSYLRVKIPSISQPYVTNKKKGELYFSVYTYKVDSDKLLYK-----VHRKYGEFYVLEQKLLEFHGTIERA-LPPKRPWDNKNLDFLEKCKLEFETYLMYLVNRTFLRNSELLHRFLT---RPTEFSFNSLIDINLGKFVKSMPMIFTKEKGQFLDQFLYNFHISCEASSQAKSNSNNDPYSSLSNSVSDPGSKSLFDARLHTRMYWNNAELNTIK----SENFMKDICSFSTRYIFYYFDSLCFFFEIITNKLAYSHFLLNFFYRIRSILVDVFQTYVKGVITRGFEKLCHEKLAVEIIHVLRDAALL-SGLNRTISEKQERRNEALTSLYQLLPGWLSIVLSDDQIKTLYSNIDRIFDFLQQPKLNKQLSYVLFDILLLELFPELTDNVVAQNQNEVP 2969
            +L EI ++++ N+++ WY   +++E F+ E++     + A ++ R  K+ +  +++QK L   + H++I    +            +Q+  L++    LHVA+ SR +E+ YL+++++ L P I P   +  ++     L++E  +G+V LP+MD +A PD +N  I + +  S    A     S+ VP LH+Y  +  +K   L+   K I     +  L+ F+ ++K   AV  +   L ++    ++L P++ +S K+ + +++++      L +    +     +   I+      Y +V +L+      E Y+ +    ++++   +  S E+F   + G      ++     W+            +PE+  +   +   SSP +F+        F +   S R S           +P   +                    + + F +++ G  IK VF + + +     S  L+ G+ D+          +S  + V  P    +LS   + IP I       K++    F +   + D   + ++     V+R+Y EFYVLE KL EFHG+   A LP KR    KN +FL   + +F+ YL  L+    L NS+LL  FL+     ++F    L D+NLGK +KS+P    KEKGQ L+ F+ +F  SCE+     S            ++  P S++  D +L   ++ NNA  + +     ++N+  ++ +    Y     D L +   ++ +   + H LL      R +  +  + Y    I     ++  E   V +I +LRD     S   R++ +KQ R       +   +P  LS  + ++     Y  +  +FD LQQP LNKQL+YVL DI + ELFPEL      +     P
Sbjct:  134 SLSEILELVLENFVHPWYREITDDEAFVDELRVTLRFIAAVLVRRTQKVDVASVITQKLLKVSMKHIEIISKARQKVKNAEY----LQQAALEEYGPDLHVALRSRRDELLYLRNLTEMLFPYILPPKAAECRS--LSLLIREVLAGSVFLPSMDYLADPDTVNHLILIFIDNSPPEDA-TEPASTLVPFLHKYSDSRSKKPSVLKLELKEIR--EQQDLLFRFMNFLKQEGAVHVLQFCLAVEEFNDRILCPELSDSEKMMLHEEVKKIYETYCLDESIDKIRFDPFIVEEIRNIAEGPYADVVKLQTMRCLFEAYEHVLSLLENVFTPMFCHSDEYFRQLLRGAESPTRNSKMSSFWD-----------WSPESPSSLCTASGSSSPASFNSLHAQFTNFPYGSQSHRHS-----------SPKNTS-------------------KRGESFGISRIGSKIKGVFKSTTMEGAMLPSYGLVEGEDDMVEEAMMVLEDDSPMEAVSTPSTPRNLSAWSITIPYIDFYDDDVKRERIPVFCIDVERNDRKAVGHETEHWSVYRRYLEFYVLESKLTEFHGSFPDAQLPSKRIIGPKNYEFLTSKREDFQEYLQKLLQHPELSNSQLLADFLSPHSMESQFLDKMLPDVNLGKIIKSVPSKLIKEKGQHLEPFIQSFFNSCESPKPKPSRPEL--------TILSPTSEN--DKKLFNDLFKNNANRSEMTEKRHNQNYFMEMITVEGVY-----DYLMYVGRVVFHIPDWLHHLL---MGGRILFKNTLEAYTDNCIQFKLNQVVQEHRLVSLITLLRDTVFCESSSPRSVQDKQSRAKRTFEEMMSYIPDVLSKCIGEE---AKYEGVRLLFDGLQQPVLNKQLTYVLLDIAIQELFPELNKQAQKETSMMAP 976
[Close]
BLAST of Sorting nexin-14 vs. TrEMBL
Match: A0A1A8QX88 (Sorting nexin 14 OS=Nothobranchius rachovii OX=451742 GN=SNX14 PE=4 SV=1)

HSP 1 Score: 248.44 bits (633), Expect = 6.046e-65
Identity = 224/914 (24.51%), Postives = 408/914 (44.64%), Query Frame = 3 
Query:  300 ALEEIFDIIIANYINSWYLGFSNNEDFIVEIKYFFHTLCAEILLRFSKISIPELVSQKFLPACINHLDICYTIQXXXXXXXXXLTPVQEILLQKMRSHLHVAMISRSEEVAYLKSISKFLIPLITPDYFSRTKNKISDHLLQECFSGTVLLPAMDSVASPDLINKFIYLLLTPSTISTALCNTQSSYVPILHRYQTAWMEKLKRLEEHPKGIECLRNEKHLYHFLQYIKSVEAVSAVNIYLEMDAIILKLLSPDMDESTKIHIFQDIERFENLIHLSDGKSNLIISSDLRRRIKEAIADGYQNVDRLRNCEIWMENYQLICQHNQSLYLSQYFES-EFFLSTIYGERLSDIDTSYECEWEDINVTGDSLNVVNPENLDNENLSRHESSPENFSFKKMSLDLFSFDFMSDRKSPIIEDQKSAFSTPDRVTXXXXXXXXXXXXXXXLSQIDKQKEFSMTKFGLSIKQVFTANSDD-----SLNLISGDLDIDNPDGSEWLSNSFGDLVDLP----DLSYLRVKIPSISQPYVTNKKKGELYFSVYTYKVDSDKLLYK-----VHRKYGEFYVLEQKLLEFHGTIERA-LPPKRPWDNKNLDFLEKCKLEFETYLMYLVNRTFLRNSELLHRFLT---RPTEFSFNSLIDINLGKFVKSMPMIFTKEKGQFLDQFLYNFHISCEASSQAKSNSNNDPYSSLSNSVSDPGSKSLFDARLHTRMYWNNAELNTIK----SENFMKDICSFSTRYIFYYFDSLCFFFEIITNKLAYSHFLLNFFYRIRSILVDVFQTYVKGVITRGFEKLCHEKLAVEIIHVLRDAALL-SGLNRTISEKQERRNEALTSLYQLLPGWLSIVLSDDQIKTLYSNIDRIFDFLQQPKLNKQLSYVLFDILLLELFPELTDNVVAQNQNEVP 2969
            +L EI ++++ N+++ WY   +++E F+ E++     + A ++ R  K+ +  +++QK L   + H++I    +            +Q+  L++    LHVA+ SR +E+ YL+++++ L P I P   +  ++     L++E  +G+V LP+MD +A PD +N  I + +  S    A     S+ VP LH+Y  +  +K   L+   K I     +  L+ F+ ++K   AV  +   L ++    ++L P++ +S K+ + +++++      L +    +     +   I+      Y +V +L+      E Y+ +    ++++   +  S E+F   + G      ++     W+            +PE+  +   +   SSP   SF  +     +F + S         Q    S+P   +                    + + F +++ G  IK VF + + +     S  L+ G+ D+          +S  + V  P    +LS   + IP I       K++    F +   + D   + ++     V+R+Y EFYVLE KL EFHG+   A LP KR    KN +FL   + +F+ YL  L+    L NS+LL  FL+     ++F    L D+NLGK +KS+P    KEKGQ L+ F+ +F  SCE+     S            ++  P S++  D +L   ++ NNA  + +     ++N+  ++ +    Y     D L +   ++ +   + H LL      R +  +  + Y    I     ++  E   V +I +LRD     S   R++ +KQ R       +   +P  LS  + ++     Y  +  +FD LQQP LNKQL+YVL DI + ELFPEL      +     P
Sbjct:  134 SLSEILELVLENFVHPWYREITDDEAFVDELRVTLRFIAAVLVRRTQKVDVASVITQKLLKVSMKHIEIISKARQKVKNAEY----LQQAALEEYGPDLHVALRSRRDELLYLRNLTEMLFPYILPPKAAECRS--LSLLIREVLAGSVFLPSMDYLADPDTVNHLILIFIDNSPPEDA-TEPASTLVPFLHKYSDSRSKKPSVLKLELKEIR--EQQDLLFRFMNFLKQEGAVHVLQFCLAVEEFNDRILCPELSDSEKMMLHEEVKKIYETYCLDESIDKIRFDPFIVEEIRNIAEGPYADVVKLQTMRCLFEAYEHVLSLLENVFTPMFCHSDEYFRQLLRGAESPTRNSKMSSFWD-----------WSPESPSSLCTASGSSSPA--SFNSLHAQFTNFPYGS---------QPHRHSSPKNTS-------------------KRGESFGISRIGSKIKGVFKSTTMEGAMLPSYGLVEGEDDMVEEAMMVLEDDSPMEAVSTPSTPRNLSAWSITIPYIDFYDDDVKRERIPVFCIDVERNDRKAVGHETEHWSVYRRYLEFYVLESKLTEFHGSFPDAQLPSKRIIGPKNYEFLTSKREDFQEYLQKLLQHPELSNSQLLADFLSPHSMESQFLDKMLPDVNLGKIIKSVPSKLIKEKGQHLEPFIQSFFNSCESPKPKPSRPEL--------TILSPTSEN--DKKLFNDLFKNNANRSEMTEKRHNQNYFMEMITVEGVY-----DYLMYVGRVVFHIPDWLHHLL---MGGRILFKNTLEAYTDNCIQFKLNQVVQEHRLVSLITLLRDTVFCESSSPRSVQDKQSRAKRTFEEMMSYIPDVLSKCIGEE---AKYEGVRLLFDGLQQPVLNKQLTYVLLDIAIQELFPELNKQAQKETSMMAP 976
[Close]
BLAST of Sorting nexin-14 vs. TrEMBL
Match: A0A3Q1IQY0 (Sorting nexin 14 OS=Anabas testudineus OX=64144 GN=SNX14 (1 of many) PE=4 SV=1)

HSP 1 Score: 246.899 bits (629), Expect = 1.472e-64
Identity = 228/925 (24.65%), Postives = 409/925 (44.22%), Query Frame = 3 
Query:  300 ALEEIFDIIIANYINSWYLGFSNNEDFIVEIKYFFHTLCAEILLRFSKISIPELVSQKFLPACINHLDICYTIQXXXXXXXXXLTPVQEILLQKMRSHLHVAMISRSEEVAYLKSISKFLIPLITPDYFSRTKNKISDHLLQECFSGTVLLPAMDSVASPDLINKFIYLLLTPSTISTALCNTQSSYVPILHRYQTAWMEKLKRLEEHPKGIECLRNEKHLYHFLQYIKSVEAVSAVNIYLEMDAIILKLLSPDMDESTKIHIFQDIERFENLIHLSDGKSNLIISSDLRRRIKEAIADGYQNVDRLRNCEIWMENYQLICQHNQSLYLSQYFES-EFFLSTIYGERLSDIDTSYECEWEDINVTGDSLNVVNPENLDNENLSRHESSPENFS--FKKMSLDLFSFDFMSDRKSPIIEDQKSAFSTPDRVTXXXXXXXXXXXXXXXLSQIDKQKEFSMTKFGLSIKQVFTANSDD-----SLNLISGDLDI----------DNPDGSEWLSNSFGDL---------VDLPDLSYLRVKIPSISQPYVTNKKKGELYFSVYTYKVDSDKLLYKVHRKYGEFYVLEQKLLEFHGTIERA-LPPKRPWDNKNLDFLEKCKLEFETYLMYLVNRTFLRNSELLHRFLT---RPTEFSFNSLIDINLGKFVKSMPMIFTKEKGQFLDQFLYNFHISCEASSQAKSNSNNDPYSSLSNSVSDPGSKSLFDARLHTRMYWNNAELNTIK----SENFMKDICSFSTRYIFYYFDSLCFFFEIITNKLAYSHFLLNFFYRIRSILVDVFQTYVKGVITRGFEKLCHEKLAVEIIHVLRDAALL-SGLNRTISEKQERRNEALTSLYQLLPGWLSIVLSDDQIKTLYSNIDRIFDFLQQPKLNKQLSYVLFDILLLELFPELTDNVVAQNQNEV 2966
            +L EI ++++ N++  WY   +++E  + E++       A ++ R  K+ +  L++QK L   + H++I    +            +Q+  L++    LHVA+ SR +E+ YL+ +++ L P I P   +  ++     L++E  +G+V LP+MD +A PD +N  I + +  S    A   T S+ VP L +Y  A  +K   L+   K I     +  L+ F+ ++K   AV  +   L ++    K+L P++ +S K+ + +++++      L +    +     +   I+      +  V +L+      E Y+ +    ++++   +  S E+F   + G      ++     W+            +PE+  +   +   SSP +F+    + +   F +  +S R S           +P   +                    + + F +++ G  IK VF + + +     S  L+ G+ D+          D+P  +    ++  +L         +D  D    R +IP        N +K           V  +   + V+R+Y EFYVLE KL EFHG+   A LP KR    KN +FL   + EF+ YL  L+    L NS+LL  FL+     ++F    L D+NLGK +KS+P    KEKGQ L+ F+ +F  SCE+     S            ++  P S++  D +L   ++ NNA  + +     ++N+  ++ +    Y     D L +   ++ +   + H LL      R +  +  +TY    +     ++  E+  V +I +LRD     S   R+I EKQ R  +    +   +P +L   + ++     Y  +  +FD LQQP LNKQL+YVL DI + ELFPEL  N   Q +  V
Sbjct:  102 SLSEILELVLENFVYPWYRDITDDEALVDELRVTLRFFAAVLVRRTQKVDVASLITQKLLKVSMKHIEIISKARQKVKNTEY----LQQAALEEYGPDLHVALRSRRDELLYLRKLTEMLFPYILPPKAADCRSLTL--LIREVLAGSVFLPSMDYLADPDTVNHLILIFIDNSPPEEATEQT-STLVPFLQKYSDARNKKSSVLKLELKEIR--EQQDLLFRFMNFLKQEGAVHVLQFCLAVEEFNDKILCPELSDSEKMMLHEEVKKIYETYCLDESIDKIRFDPFIVEEIRNIAEGPFAEVVKLQTMRCLFEAYEHVLSLLENVFTPMFCHSDEYFRQLLRGAESPARNSKMSSSWD-----------WSPESPSSLFTASGSSSPASFNSLHAQSTFTTFPYGSLSHRHS-----------SPKNTS-------------------KRGESFGISRIGSKIKGVFKSTTMEGAMLPSYGLVEGEDDMVEEAMMVLEDDSPMEAASTPSTPRNLSAWNITIPYIDFYDDDVKRERIPVFCIDVERNDRKA----------VGHETEHWSVYRRYLEFYVLESKLTEFHGSFPDAQLPSKRIIGPKNYEFLTSKREEFQEYLQKLLQHPELSNSQLLADFLSPHSMESQFLDKMLPDVNLGKIIKSVPSKLIKEKGQHLEPFIQSFFNSCESPKPKPSRPEL--------TILSPTSEN--DKKLFNDLFKNNANRSEMTEKRHNQNYFMEMITVEGVY-----DYLMYVGRVVFHIPDWFHHLL---MGGRILFKNTLETYTDYYLQYKLNQVVQEQRLVSLITLLRDTVFCESSPPRSIQEKQRRAKKTFEEMMSYIPDFLGKCIGEE---AKYEGVRLLFDGLQQPILNKQLTYVLLDITIQELFPEL--NKQGQKETSV 943
[Close]
BLAST of Sorting nexin-14 vs. TrEMBL
Match: A0A1A8DC69 (Sorting nexin 14 OS=Nothobranchius kadleci OX=1051664 GN=SNX14 PE=4 SV=1)

HSP 1 Score: 246.899 bits (629), Expect = 2.641e-64
Identity = 226/919 (24.59%), Postives = 413/919 (44.94%), Query Frame = 3 
Query:  300 ALEEIFDIIIANYINSWYLGFSNNEDFIVEIKYFFHTLCAEILLRFSKISIPELVSQKFLPACINHLDICYTIQXXXXXXXXXLTPVQEILLQKMRSHLHVAMISRSEEVAYLKSISKFLIPLITPDYFSRTKNKISDHLLQECFSGTVLLPAMDSVASPDLINKFIYLLLTPSTISTALCNTQSSYVPILHRYQTAWMEKLKRLEEHPKGIECLRNEKHLYHFLQYIKSVEAVSAVNIYLEMDAIILKLLSPDMDESTKIHIFQDIERFENLIHLSDGKSNLIISSDLRRRIKEAIADGYQNVDRLRNCEIWMENYQLICQHNQSLYLSQYFES-EFFLSTIYGERLSDIDTSYECEWEDINVTGDSLNVV-----NPENLDNENLSRHESSPENFSFKKMSLDLFSFDFMSDRKSPIIEDQKSAFSTPDRVTXXXXXXXXXXXXXXXLSQIDKQKEFSMTKFGLSIKQVFTANSDD-----SLNLISGDLDIDNPDGSEWLSNSFGDLVDLP----DLSYLRVKIPSISQPYVTNKKKGELYFSVYTYKVDSDKLLYK-----VHRKYGEFYVLEQKLLEFHGTIERA-LPPKRPWDNKNLDFLEKCKLEFETYLMYLVNRTFLRNSELLHRFLT---RPTEFSFNSLIDINLGKFVKSMPMIFTKEKGQFLDQFLYNFHISCEASSQAKSNSNNDPYSSLSNSVSDPGSKSLFDARLHTRMYWNNAELNTIK----SENFMKDICSFSTRYIFYYFDSLCFFFEIITNKLAYSHFLLNFFYRIRSILVDVFQTYVKGVITRGFEKLCHEKLAVEIIHVLRDAALL-SGLNRTISEKQERRNEALTSLYQLLPGWLSIVLSDDQIKTLYSNIDRIFDFLQQPKLNKQLSYVLFDILLLELFPELTDNVVAQNQNEVP 2969
            +L EI ++++ N+++ WY   +++E F+ E++     + A ++ R  K+ +  +++QK L   + H++I    +            +Q+  L++    LHVA+ SR +E+ YL+++++ L P I P   +  ++     L++E  +G+V LP+MD +A PD +N  I + +  S    A     S+ VP LH+Y  +  +K   L+   K I     +  L+ F+ ++K   AV  +   L ++    ++L P++ +S K+ + +++++      L +    +     +   I+      Y +V +L+      E Y+ +    ++++   +  S E+F   + G      ++        ++ T  SL+ +     +PE+  +   +   SSP   SF  +     +F + S         Q    S+P   +                    + + F +++ G  IK VF + + +     S  L+ G+ D+          +S  + V  P    +LS   + IP I       K++    F +   + D   + ++     V+R+Y EFYVLE KL EFHG+   A LP KR    KN +FL   + +F+ YL  L+    L NS+LL  FL+     ++F    L D+NLGK +KS+P    KEKGQ L+ F+ +F  SCE+     S            ++  P S++  D +L   ++ NNA  + +     ++N+  ++ +    Y     D L +   ++ +   + H LL      R +  +  + Y    I     ++  E   V +I +LRD     S   R++ +KQ R       +   +P  LS  + ++     Y  +  +FD LQQP LNKQL+YVL DI + ELFPEL      +     P
Sbjct:  134 SLSEILELVLENFVHPWYREITDDEAFVDELRVTLRFIAAVLVRRTQKVDVASVITQKLLKVSMKHIEIISKARQKVKNAEC----LQQAALEEYGPDLHVALRSRRDELLYLRNLTEMLFPYILPPKAAECRS--LSLLIREVLAGSVFLPSMDYLADPDTVNHLILIFIDSSPPEDA-TEPASTLVPFLHKYSDSRNKKPSVLKLELKEIR--EQQDLLFRFMNFLKQEGAVHVLQFCLAVEEFNDRILCPELSDSEKMMLHEEVKKIYETYCLDESIDKIRFDPFIVEEIRNIAEGPYADVVKLQTMRCLFEAYEHVLSLLENVFTPMFCHSDEYFRQLLRGAESPTRNSK-------MSRTSLSLDDIRFWDWSPESPSSLCTASGSSSPA--SFNSLHAQFTNFPYGS---------QPHRHSSPKNTS-------------------KRGESFGISRIGSKIKGVFKSTTMEGAMLPSYGLVEGEDDMVEEAMMVLEDDSPMEAVSTPSTPRNLSAWSITIPYIDFYDDDAKRERIPVFCIDVERNDRKAVGHETEHWSVYRRYLEFYVLESKLTEFHGSFPDAQLPSKRIIGPKNYEFLTSKREDFQEYLQKLLQHPELSNSQLLADFLSPHSMESQFLDKMLPDVNLGKIIKSVPSKLIKEKGQHLEPFIQSFFNSCESPKPKPSRPEL--------TILSPTSEN--DKKLFNDLFKNNANRSEMTEKRHNQNYFMEMITVEGVY-----DYLMYVGRVVFHIPDWLHHLL---MGGRILFKNTLEAYTDNCIQFKLNQVVQEHRLVSLITLLRDTVFCESSSPRSVQDKQSRAKRTFEEMMSYIPDVLSKCIGEE---AKYEGVRLLFDGLQQPVLNKQLTYVLLDIAIQELFPELNKQAQKETSMMAP 985
[Close]
BLAST of Sorting nexin-14 vs. Ensembl Cavefish
Match: SNX14 (sorting nexin 14 [Source:NCBI gene;Acc:103025420])

HSP 1 Score: 236.884 bits (603), Expect = 2.399e-64
Identity = 234/906 (25.83%), Postives = 400/906 (44.15%), Query Frame = 3 
Query:  300 ALEEIFDIIIANYINSWYLGFSNNEDFIVEIKYFFHTLCAEILLRFSKISIPELVSQKFLPACINHLDICYTIQXXXXXXXXXLTPVQEILLQKMRSHLHVAMISRSEEVAYLKSISKFLIPLITPDYFSRTKNKISDHLLQECFSGTVLLPAMDSVASPDLINKFIYLLLTPSTISTALCNTQSSYVPILHRYQTAWMEKLKRLEEHPKGIECLRNEKHLYHFLQYIKSVEAVSAVNIYLEMDAIILKLLSPDMDESTKIHIFQDIERFENLIHLSDGKSNLIISSDLRRRIKEAIADGYQNVDRLRNCEIWMENYQLICQHNQSLYLSQYFES-EFFLSTIYGERLSDIDTSYECEWEDINVTGDSLNVVNPENLDNENLSRHESSPENFSFKKMSLDLFSFDFMSDRKSPIIEDQKSAFS-TPDRVTXXXXXXXXXXXXXXXLSQIDKQKE-FSMTKFGLSIKQVFTANSDDSLNLISGDLDIDNPDGSEWLSNSFGDLVDLPDLSYLRVKIP------SISQPYVT---NKKKGELYFSVYTYKVDSDKLL--------YKVHRKYGEFYVLEQKLLEFHGTIERA-LPPKRPWDNKNLDFLEKCKLEFETYLMYLVNRTFLRNSELLHRFLT---RPTEFSFNSLIDINLGKFVKSMPMIFTKEKGQFLDQFLYNFHISCEASSQAKSNSNNDPYSSLSNSVSDPGSKSLFDARLHTRMYWNNAE----LNTIKSENFMKDICSFSTRYIFYYFDSLCFFFEIITNKLAYSHFLLNFFYRIRSILVDVFQTYVKGVITRGFEKLCHEKLAVEIIHVLRDAALLSGLN-RTISEKQERRNEALTSLYQLLPGWLSIVLSDDQIKTLYSNIDRIFDFLQQPKLNKQLSYVLFDILLLELFPEL 2930
            +L EI ++++ N++  WY   +++E F+ E++     + A ++ R  ++ IP L++ K L   + H++I    +     +      +Q+  L++    LHVA+ SR +E+ YL+ +++ L P I P     T  +    L++E  +G+V LP+MD +A PD +N  + L+   ++   A     S+ VP L +Y     +K   L+   K I     +  L+ F+ ++K   AV  +   L ++    K+L P++ ++ K+ + +++ +      L +    +     +   IK      Y  V +L+      E Y+ +    ++++   +  S E+F   + G                           +P    N  LSR+  S ++      S D   +D+    +S  I    S  + +P   +    P      +   L    K+ E F +++ G  IK VF + + +   L S  L     D  E       D  DLP  +      P      SI+ PYV    ++ K E    VY   V+ +           + V+R+Y EFYVLE KL EFHG+   A LP KR    KN +FL   + EF+ YL  L+    L NS+LL  FL+     ++F    L D+NLGK +KS+P    KEKGQ L+ F+  F  SCE+     S     P  ++ +  S+  +K LF+      +Y NNA     +    ++N+  ++ +    Y     D L F   ++ +   + H LL      R +  +  + Y    +     ++  E   V +I +LRDA      + R++ +KQ+R       +   +P      + +D        I  +FD LQQP LNKQL+Y+L DI + ELFPEL
Sbjct:  132 SLSEILELVLENFVYPWYRDITDDEAFVDELRVTLRFVAAVLVRRAQRVDIPSLITLKLLKVAMKHIEIIAKARQKVKNSEY----LQQAALEEYGPDLHVALRSRRDELLYLRKLTEMLFPYILPP--KGTDCRSLTLLIKEVLAGSVFLPSMDYLADPDTVNHLL-LIFIDNSPPEAATEPASALVPFLQKYADVRNKKASGLKLELKEIR--EQQDLLFRFMNFLKQEGAVHVLQFCLTVEEFNDKILCPELSDAEKLMLHEEVRKIYETYCLDESVDKIQFDPFIVEEIKNIAEGPYSGVVKLQTMRCLFEAYEHVLSLLENVFTPMFCHSDEYFRQLLRGAE-------------------------SPTR--NSRLSRNSVSLDDIR----SAD---WDYTLSLESASISPGSSPTTVSPQFSSIHTLPSSSNAWRASALKNTSKRGESFGISRIGSKIKGVFKSTTMEGAMLPSYGLAEGEDDMVEEAIMVMED--DLPMEAISTPSTPRNLSAWSITIPYVDLFDDEIKKE-RIPVYCIDVERNDRRAVGHETEHWSVYRRYLEFYVLESKLTEFHGSFPDAQLPSKRIIGPKNYEFLTSKREEFQEYLQKLLQHPELSNSQLLADFLSPHSMESQFHDKMLPDVNLGKIIKSVPSKLIKEKGQHLEPFIQAFFNSCESPKPKPSR----PELTILSPTSE-NNKKLFN-----ELYKNNANRSENMEKRHNQNYFMEMITVEGVY-----DYLMFVGRVVFHIPDWLHHLL---MGGRILFKNTLEAYTDYYLQNKLNQVFQEHRVVSLITLLRDAVFCENSDPRSLEDKQKRAKRTFEEMRNYIPDLFGKCIGEDAKS---EGIRLLFDGLQQPVLNKQLTYILLDIAIQELFPEL 970
[Close]
BLAST of Sorting nexin-14 vs. Ensembl Cavefish
Match: SNX14 (sorting nexin 14 [Source:NCBI gene;Acc:103025420])

HSP 1 Score: 235.343 bits (599), Expect = 6.304e-64
Identity = 231/906 (25.50%), Postives = 398/906 (43.93%), Query Frame = 3 
Query:  300 ALEEIFDIIIANYINSWYLGFSNNEDFIVEIKYFFHTLCAEILLRFSKISIPELVSQKFLPACINHLDICYTIQXXXXXXXXXLTPVQEILLQKMRSHLHVAMISRSEEVAYLKSISKFLIPLITPDYFSRTKNKISDHLLQECFSGTVLLPAMDSVASPDLINKFIYLLLTPSTISTALCNTQSSYVPILHRYQTAWMEKLKRLEEHPKGIECLRNEKHLYHFLQYIKSVEAVSAVNIYLEMDAIILKLLSPDMDESTKIHIFQDIERFENLIHLSDGKSNLIISSDLRRRIKEAIADGYQNVDRLRNCEIWMENYQLICQHNQSLYLSQYFES-EFFLSTIYGERLSDIDT--SYECEWEDINVTGDSLNVVNPENLDNENLSRHESSPENFSFKKMSLDLFSFDFMSDRKSPIIEDQKSAFSTPDRVTXXXXXXXXXXXXXXXLSQIDKQKEFSMTKFGLSIKQVFTANSDDSLNLISGDLDIDNPDGSEWLSNSFGDLVDLPDLSYLRVKIP------SISQPYVT---NKKKGELYFSVYTYKVDSDKLL--------YKVHRKYGEFYVLEQKLLEFHGTIERA-LPPKRPWDNKNLDFLEKCKLEFETYLMYLVNRTFLRNSELLHRFLT---RPTEFSFNSLIDINLGKFVKSMPMIFTKEKGQFLDQFLYNFHISCEASSQAKSNSNNDPYSSLSNSVSDPGSKSLFDARLHTRMYWNNAE----LNTIKSENFMKDICSFSTRYIFYYFDSLCFFFEIITNKLAYSHFLLNFFYRIRSILVDVFQTYVKGVITRGFEKLCHEKLAVEIIHVLRDAALLSGLN-RTISEKQERRNEALTSLYQLLPGWLSIVLSDDQIKTLYSNIDRIFDFLQQPKLNKQLSYVLFDILLLELFPEL 2930
            +L EI ++++ N++  WY   +++E F+ E++     + A ++ R  ++ IP L++ K L   + H++I    +     +      +Q+  L++    LHVA+ SR +E+ YL+ +++ L P I P     T  +    L++E  +G+V LP+MD +A PD +N  + L+   ++   A     S+ VP L +Y     +K   L+   K I     +  L+ F+ ++K   AV  +   L ++    K+L P++ ++ K+ + +++ +      L +    +     +   IK      Y  V +L+      E Y+ +    ++++   +  S E+F   + G      ++  S   +W D  ++ +S ++ +P            SSP   S +  S+        + R S +    K   S                              F +++ G  IK VF + + +   L S  L     D  E       D  DLP  +      P      SI+ PYV    ++ K E    VY   V+ +           + V+R+Y EFYVLE KL EFHG+   A LP KR    KN +FL   + EF+ YL  L+    L NS+LL  FL+     ++F    L D+NLGK +KS+P    KEKGQ L+ F+  F  SCE+     S     P  ++ +  S+  +K LF+      +Y NNA     +    ++N+  ++ +    Y     D L F   ++ +   + H LL      R +  +  + Y    +     ++  E   V +I +LRDA      + R++ +KQ+R       +   +P      + +D        I  +FD LQQP LNKQL+Y+L DI + ELFPEL
Sbjct:  132 SLSEILELVLENFVYPWYRDITDDEAFVDELRVTLRFVAAVLVRRAQRVDIPSLITLKLLKVAMKHIEIIAKARQKVKNSEY----LQQAALEEYGPDLHVALRSRRDELLYLRKLTEMLFPYILPP--KGTDCRSLTLLIKEVLAGSVFLPSMDYLADPDTVNHLL-LIFIDNSPPEAATEPASALVPFLQKYADVRNKKASGLKLELKEIR--EQQDLLFRFMNFLKQEGAVHVLQFCLTVEEFNDKILCPELSDAEKLMLHEEVRKIYETYCLDESVDKIQFDPFIVEEIKNIAEGPYSGVVKLQTMRCLFEAYEHVLSLLENVFTPMFCHSDEYFRQLLRGAESPTRNSRLSSSADW-DYTLSLESASI-SPG-----------SSPTTVSPQFSSIHTLPSSSNAWRASALKNTSKRGES------------------------------FGISRIGSKIKGVFKSTTMEGAMLPSYGLAEGEDDMVEEAIMVMED--DLPMEAISTPSTPRNLSAWSITIPYVDLFDDEIKKE-RIPVYCIDVERNDRRAVGHETEHWSVYRRYLEFYVLESKLTEFHGSFPDAQLPSKRIIGPKNYEFLTSKREEFQEYLQKLLQHPELSNSQLLADFLSPHSMESQFHDKMLPDVNLGKIIKSVPSKLIKEKGQHLEPFIQAFFNSCESPKPKPSR----PELTILSPTSE-NNKKLFN-----ELYKNNANRSENMEKRHNQNYFMEMITVEGVY-----DYLMFVGRVVFHIPDWLHHLL---MGGRILFKNTLEAYTDYYLQNKLNQVFQEHRVVSLITLLRDAVFCENSDPRSLEDKQKRAKRTFEEMRNYIPDLFGKCIGEDAKS---EGIRLLFDGLQQPVLNKQLTYILLDIAIQELFPEL 961
[Close]
BLAST of Sorting nexin-14 vs. Ensembl Cavefish
Match: SNX14 (sorting nexin 14 [Source:NCBI gene;Acc:103025420])

HSP 1 Score: 148.673 bits (374), Expect = 3.574e-36
Identity = 138/455 (30.33%), Postives = 209/455 (45.93%), Query Frame = 3 
Query: 1644 KQKEFSMTKFGLSIKQVFTANSDDSLNLISGDLDIDNPDGSEWLSNSFGDLVDLPDLSYLRVKIP------SISQPYVT---NKKKGELYFSVYTYKVDSDKLL--------YKVHRKYGEFYVLEQKLLEFHGTIERA-LPPKRPWDNKNLDFLEKCKLEFETYLMYLVNRTFLRNSELLHRFLT---RPTEFSFNSLIDINLGKFVKSMPMIFTKEKGQFLDQFLYNFHISCEASSQAKSNSNNDPYSSLSNSVSDPGSKSLFDARLHTRMYWNNAE----LNTIKSENFMKDICSFSTRYIFYYFDSLCFFFEIITNKLAYSHFLLNFFYRIRSILVDVFQTYVKGVITRGFEKLCHEKLAVEIIHVLRDAALLSGLN-RTISEKQERRNEALTSLYQLLPGWLSIVLSDDQIKTLYSNIDRIFDFLQQPKLNKQLSYVLFDILLLELFPEL 2930
            + + F +++ G  IK VF + + +   L S  L     D  E       D  DLP  +      P      SI+ PYV    ++ K E    VY   V+ +           + V+R+Y EFYVLE KL EFHG+   A LP KR    KN +FL   + EF+ YL  L+    L NS+LL  FL+     ++F    L D+NLGK +KS+P    KEKGQ L+ F+  F  SCE+     S     P  ++ +  S+  +K LF+      +Y NNA     +    ++N+  ++ +    Y     D L F   ++ +   + H LL      R +  +  + Y    +     ++  E   V +I +LRDA      + R++ +KQ+R       +   +P      + +D        I  +FD LQQP LNKQL+Y+L DI + ELFPEL
Sbjct:  423 RGESFGISRIGSKIKGVFKSTTMEGAMLPSYGLAEGEDDMVEEAIMVMED--DLPMEAISTPSTPRNLSAWSITIPYVDLFDDEIKKE-RIPVYCIDVERNDRRAVGHETEHWSVYRRYLEFYVLESKLTEFHGSFPDAQLPSKRIIGPKNYEFLTSKREEFQEYLQKLLQHPELSNSQLLADFLSPHSMESQFHDKMLPDVNLGKIIKSVPSKLIKEKGQHLEPFIQAFFNSCESPKPKPSR----PELTILSPTSE-NNKKLFN-----ELYKNNANRSENMEKRHNQNYFMEMITVEGVY-----DYLMFVGRVVFHIPDWLHHLL---MGGRILFKNTLEAYTDYYLQNKLNQVFQEHRVVSLITLLRDAVFCENSDPRSLEDKQKRAKRTFEEMRNYIPDLFGKCIGEDAKS---EGIRLLFDGLQQPVLNKQLTYILLDIAIQELFPEL 853

HSP 2 Score: 90.5077 bits (223), Expect = 4.662e-18
Identity = 69/300 (23.00%), Postives = 138/300 (46.00%), Query Frame = 3 
Query:  435 FSKISIPELVSQKFLPACINHLDICYTIQXXXXXXXXXLTPVQEILLQKMRSHLHVAMISRSEEVAYLKSISKFLIPLITPDYFSRTKNKISDHLLQECFSGTVLLPAMDSVASPDLINKFIYLLLTPSTISTALCNTQSSYVPILHRYQTAWMEKLKRLEEHPKGIECLRNEKHLYHFLQYIKSVEAVSAVNIYLEMDAIILKLLSPDMDESTKIHIFQDIERFENLIHLSDGKSNLIISSDLRRRIKEAIADGYQNVDRLRNCEIWMENYQLICQHNQSLYLSQYFES-EFFLSTIYG 1331
             S++ IP L++ K L   + H++I    +     +      +Q+  L++    LHVA+ SR +E+ YL+ +++ L P I P     T  +    L++E  +G+V LP+MD +A PD +N  + L+   ++   A     S+ VP L +Y     +K   L+   K I     +  L+ F+ ++K   AV  +   L ++    K+L P++ ++ K+ + +++ +      L +    +     +   IK      Y  V +L+      E Y+ +    ++++   +  S E+F   + G
Sbjct:  116 LSEVDIPSLITLKLLKVAMKHIEIIAKARQKVKNSEY----LQQAALEEYGPDLHVALRSRRDELLYLRKLTEMLFPYILPP--KGTDCRSLTLLIKEVLAGSVFLPSMDYLADPDTVNHLL-LIFIDNSPPEAATEPASALVPFLQKYADVRNKKASGLKLELKEIR--EQQDLLFRFMNFLKQEGAVHVLQFCLTVEEFNDKILCPELSDAEKLMLHEEVRKIYETYCLDESVDKIQFDPFIVEEIKNIAEGPYSGVVKLQTMRCLFEAYEHVLSLLENVFTPMFCHSDEYFRQLLRG 406
[Close]
BLAST of Sorting nexin-14 vs. Ensembl Cavefish
Match: SNX14 (sorting nexin 14 [Source:NCBI gene;Acc:103025420])

HSP 1 Score: 148.673 bits (374), Expect = 4.278e-36
Identity = 138/455 (30.33%), Postives = 209/455 (45.93%), Query Frame = 3 
Query: 1644 KQKEFSMTKFGLSIKQVFTANSDDSLNLISGDLDIDNPDGSEWLSNSFGDLVDLPDLSYLRVKIP------SISQPYVT---NKKKGELYFSVYTYKVDSDKLL--------YKVHRKYGEFYVLEQKLLEFHGTIERA-LPPKRPWDNKNLDFLEKCKLEFETYLMYLVNRTFLRNSELLHRFLT---RPTEFSFNSLIDINLGKFVKSMPMIFTKEKGQFLDQFLYNFHISCEASSQAKSNSNNDPYSSLSNSVSDPGSKSLFDARLHTRMYWNNAE----LNTIKSENFMKDICSFSTRYIFYYFDSLCFFFEIITNKLAYSHFLLNFFYRIRSILVDVFQTYVKGVITRGFEKLCHEKLAVEIIHVLRDAALLSGLN-RTISEKQERRNEALTSLYQLLPGWLSIVLSDDQIKTLYSNIDRIFDFLQQPKLNKQLSYVLFDILLLELFPEL 2930
            + + F +++ G  IK VF + + +   L S  L     D  E       D  DLP  +      P      SI+ PYV    ++ K E    VY   V+ +           + V+R+Y EFYVLE KL EFHG+   A LP KR    KN +FL   + EF+ YL  L+    L NS+LL  FL+     ++F    L D+NLGK +KS+P    KEKGQ L+ F+  F  SCE+     S     P  ++ +  S+  +K LF+      +Y NNA     +    ++N+  ++ +    Y     D L F   ++ +   + H LL      R +  +  + Y    +     ++  E   V +I +LRDA      + R++ +KQ+R       +   +P      + +D        I  +FD LQQP LNKQL+Y+L DI + ELFPEL
Sbjct:  493 RGESFGISRIGSKIKGVFKSTTMEGAMLPSYGLAEGEDDMVEEAIMVMED--DLPMEAISTPSTPRNLSAWSITIPYVDLFDDEIKKE-RIPVYCIDVERNDRRAVGHETEHWSVYRRYLEFYVLESKLTEFHGSFPDAQLPSKRIIGPKNYEFLTSKREEFQEYLQKLLQHPELSNSQLLADFLSPHSMESQFHDKMLPDVNLGKIIKSVPSKLIKEKGQHLEPFIQAFFNSCESPKPKPSR----PELTILSPTSE-NNKKLFN-----ELYKNNANRSENMEKRHNQNYFMEMITVEGVY-----DYLMFVGRVVFHIPDWLHHLL---MGGRILFKNTLEAYTDYYLQNKLNQVFQEHRVVSLITLLRDAVFCENSDPRSLEDKQKRAKRTFEEMRNYIPDLFGKCIGEDAKS---EGIRLLFDGLQQPVLNKQLTYILLDIAIQELFPEL 923

HSP 2 Score: 115.931 bits (289), Expect = 7.755e-26
Identity = 79/345 (22.90%), Postives = 164/345 (47.54%), Query Frame = 3 
Query:  300 ALEEIFDIIIANYINSWYLGFSNNEDFIVEIKYFFHTLCAEILLRFSKISIPELVSQKFLPACINHLDICYTIQXXXXXXXXXLTPVQEILLQKMRSHLHVAMISRSEEVAYLKSISKFLIPLITPDYFSRTKNKISDHLLQECFSGTVLLPAMDSVASPDLINKFIYLLLTPSTISTALCNTQSSYVPILHRYQTAWMEKLKRLEEHPKGIECLRNEKHLYHFLQYIKSVEAVSAVNIYLEMDAIILKLLSPDMDESTKIHIFQDIERFENLIHLSDGKSNLIISSDLRRRIKEAIADGYQNVDRLRNCEIWMENYQLICQHNQSLYLSQYFES-EFFLSTIYG 1331
            +L EI ++++ N++  WY   +++E F+ E++     + A ++ R  ++ IP L++ K L   + H++I    +     +      +Q+  L++    LHVA+ SR +E+ YL+ +++ L P I P     T  +    L++E  +G+V LP+MD +A PD +N  + L+   ++   A     S+ VP L +Y     +K   L+   K I     +  L+ F+ ++K   AV  +   L ++    K+L P++ ++ K+ + +++ +      L +    +     +   IK      Y  V +L+      E Y+ +    ++++   +  S E+F   + G
Sbjct:  132 SLSEILELVLENFVYPWYRDITDDEAFVDELRVTLRFVAAVLVRRAQRVDIPSLITLKLLKVAMKHIEIIAKARQKVKNSEY----LQQAALEEYGPDLHVALRSRRDELLYLRKLTEMLFPYILPP--KGTDCRSLTLLIKEVLAGSVFLPSMDYLADPDTVNHLL-LIFIDNSPPEAATEPASALVPFLQKYADVRNKKASGLKLELKEIR--EQQDLLFRFMNFLKQEGAVHVLQFCLTVEEFNDKILCPELSDAEKLMLHEEVRKIYETYCLDESVDKIQFDPFIVEEIKNIAEGPYSGVVKLQTMRCLFEAYEHVLSLLENVFTPMFCHSDEYFRQLLRG 467
[Close]
BLAST of Sorting nexin-14 vs. Ensembl Cavefish
Match: SNX14 (sorting nexin 14 [Source:NCBI gene;Acc:103025420])

HSP 1 Score: 148.673 bits (374), Expect = 4.453e-36
Identity = 138/455 (30.33%), Postives = 209/455 (45.93%), Query Frame = 3 
Query: 1644 KQKEFSMTKFGLSIKQVFTANSDDSLNLISGDLDIDNPDGSEWLSNSFGDLVDLPDLSYLRVKIP------SISQPYVT---NKKKGELYFSVYTYKVDSDKLL--------YKVHRKYGEFYVLEQKLLEFHGTIERA-LPPKRPWDNKNLDFLEKCKLEFETYLMYLVNRTFLRNSELLHRFLT---RPTEFSFNSLIDINLGKFVKSMPMIFTKEKGQFLDQFLYNFHISCEASSQAKSNSNNDPYSSLSNSVSDPGSKSLFDARLHTRMYWNNAE----LNTIKSENFMKDICSFSTRYIFYYFDSLCFFFEIITNKLAYSHFLLNFFYRIRSILVDVFQTYVKGVITRGFEKLCHEKLAVEIIHVLRDAALLSGLN-RTISEKQERRNEALTSLYQLLPGWLSIVLSDDQIKTLYSNIDRIFDFLQQPKLNKQLSYVLFDILLLELFPEL 2930
            + + F +++ G  IK VF + + +   L S  L     D  E       D  DLP  +      P      SI+ PYV    ++ K E    VY   V+ +           + V+R+Y EFYVLE KL EFHG+   A LP KR    KN +FL   + EF+ YL  L+    L NS+LL  FL+     ++F    L D+NLGK +KS+P    KEKGQ L+ F+  F  SCE+     S     P  ++ +  S+  +K LF+      +Y NNA     +    ++N+  ++ +    Y     D L F   ++ +   + H LL      R +  +  + Y    +     ++  E   V +I +LRDA      + R++ +KQ+R       +   +P      + +D        I  +FD LQQP LNKQL+Y+L DI + ELFPEL
Sbjct:  484 RGESFGISRIGSKIKGVFKSTTMEGAMLPSYGLAEGEDDMVEEAIMVMED--DLPMEAISTPSTPRNLSAWSITIPYVDLFDDEIKKE-RIPVYCIDVERNDRRAVGHETEHWSVYRRYLEFYVLESKLTEFHGSFPDAQLPSKRIIGPKNYEFLTSKREEFQEYLQKLLQHPELSNSQLLADFLSPHSMESQFHDKMLPDVNLGKIIKSVPSKLIKEKGQHLEPFIQAFFNSCESPKPKPSR----PELTILSPTSE-NNKKLFN-----ELYKNNANRSENMEKRHNQNYFMEMITVEGVY-----DYLMFVGRVVFHIPDWLHHLL---MGGRILFKNTLEAYTDYYLQNKLNQVFQEHRVVSLITLLRDAVFCENSDPRSLEDKQKRAKRTFEEMRNYIPDLFGKCIGEDAKS---EGIRLLFDGLQQPVLNKQLTYILLDIAIQELFPEL 914

HSP 2 Score: 115.931 bits (289), Expect = 7.871e-26
Identity = 79/345 (22.90%), Postives = 164/345 (47.54%), Query Frame = 3 
Query:  300 ALEEIFDIIIANYINSWYLGFSNNEDFIVEIKYFFHTLCAEILLRFSKISIPELVSQKFLPACINHLDICYTIQXXXXXXXXXLTPVQEILLQKMRSHLHVAMISRSEEVAYLKSISKFLIPLITPDYFSRTKNKISDHLLQECFSGTVLLPAMDSVASPDLINKFIYLLLTPSTISTALCNTQSSYVPILHRYQTAWMEKLKRLEEHPKGIECLRNEKHLYHFLQYIKSVEAVSAVNIYLEMDAIILKLLSPDMDESTKIHIFQDIERFENLIHLSDGKSNLIISSDLRRRIKEAIADGYQNVDRLRNCEIWMENYQLICQHNQSLYLSQYFES-EFFLSTIYG 1331
            +L EI ++++ N++  WY   +++E F+ E++     + A ++ R  ++ IP L++ K L   + H++I    +     +      +Q+  L++    LHVA+ SR +E+ YL+ +++ L P I P     T  +    L++E  +G+V LP+MD +A PD +N  + L+   ++   A     S+ VP L +Y     +K   L+   K I     +  L+ F+ ++K   AV  +   L ++    K+L P++ ++ K+ + +++ +      L +    +     +   IK      Y  V +L+      E Y+ +    ++++   +  S E+F   + G
Sbjct:  132 SLSEILELVLENFVYPWYRDITDDEAFVDELRVTLRFVAAVLVRRAQRVDIPSLITLKLLKVAMKHIEIIAKARQKVKNSEY----LQQAALEEYGPDLHVALRSRRDELLYLRKLTEMLFPYILPP--KGTDCRSLTLLIKEVLAGSVFLPSMDYLADPDTVNHLL-LIFIDNSPPEAATEPASALVPFLQKYADVRNKKASGLKLELKEIR--EQQDLLFRFMNFLKQEGAVHVLQFCLTVEEFNDKILCPELSDAEKLMLHEEVRKIYETYCLDESVDKIQFDPFIVEEIKNIAEGPYSGVVKLQTMRCLFEAYEHVLSLLENVFTPMFCHSDEYFRQLLRG 467
[Close]
BLAST of Sorting nexin-14 vs. Ensembl Sea Lamprey
Match: snx14 (sorting nexin 14 [Source:NCBI gene;Acc:555970])

HSP 1 Score: 141.354 bits (355), Expect = 1.919e-34
Identity = 123/392 (31.38%), Postives = 188/392 (47.96%), Query Frame = 3 
Query: 1809 DLSYLRVKIPSISQPYVTNKKKGELYFSVYTYKVDS-----DKLLYKVHRKYGEFYVLEQKLLEFHGTIERA-LPPKRPWDNKNLDFLEKCKLEFETYLMYLVNRTFLRNSELLHRFLTRPTE--FSFNSLIDINLGKFVKSMPMIFTKEKGQFLDQFLYNFHISCEASSQAKSNSNNDPYSSLSNSVSDPGSKSLFDARLHTRMYWNNAE----LNTIKSENFMKDICSFSTRYIFYYFDSLCFFFEIITNKLAYSHFLLNFFYRIRSILVDVFQTYVKGVITRGFEKLCHEKLAVEIIHVLRDAALL-SGLNRTISEKQERRNEALTSLYQLLPGWLSIVLSDDQIKTLYSNIDRIFDFLQQPKLNKQLSYVLFDILLLELFPELTDNVV 2945
            DLS  RV   S+   Y   +K+    F +   ++D          + V RKY EFY L+ KL EFHG+   A LPPK+   +K L+F+E     FE YL  L+    L +S+LL  FL+R  E  FS  +  D+N+GK  K++P +  KE+GQ L+ F+ +F +SCEA  + K   N         +V  P  K   DA++ + ++ +NA      +  +  NF         R +   +D L F   I+     + H LL      R +L    + Y    +     +L  E    E++H+LRD        +RT  E++ R  +    +   +P      + +D     Y  I  +FD LQQP LNKQL+Y+L DI++LELFPE+   ++
Sbjct:  530 DLSSWRVCAVSLDVGYDDARKEKTFLFLIEVQRLDGKPDEPGHNHWTVKRKYDEFYALQTKLTEFHGSFPDAQLPPKKVIGSKGLEFMESKTKGFELYLQVLLKHPTLTHSQLLVDFLSRDGEAQFSDKTFPDVNIGKIFKAVPRLM-KERGQHLEPFIQSFVVSCEAP-KPKPGRNE-------ITVLSPSQKC--DAKIFSPLFGDNASRVDGCDKKRGPNFF-----VEERTVSGIYDYLLFVGRIVFRIPDWLHQLL---MGGRILLKHTLEAYCDHYLAYKIGQLLQEHRLEELLHLLRDVLFFDKDPSRTPEEQRLRAQQTFQGMMAYIPDMAVRCIGED---ARYEGIKLLFDGLQQPLLNKQLTYLLLDIVVLELFPEIDQKLI 899

HSP 2 Score: 117.087 bits (292), Expect = 5.683e-27
Identity = 101/451 (22.39%), Postives = 215/451 (47.67%), Query Frame = 3 
Query:   75 FMIYLAIIYGI--FFFLLG--YLIK---FLQTPKNVKQEEDFYLKFKNFRFFSLNDFKNSKKKPNLYLVENKX---XXXXXXXXXALEEIFDIIIANYINSWYLGFSNNEDFIVEIKYFFHTLCAEILLRFSKISIPELVSQKFLPACINHLDICYTIQXXXXXXXXXLTPVQEILLQKMRSHLHVAMISRSEEVAYLKSISKFLIPLITPDYFSRTKNKISDHLLQECFSGTVLLPAMDSVASPDLINKFIYLLLTPSTISTALCNTQSSYVPILHRYQTAWMEKLKRLEEHPKGIECLRNEKHLYHFLQYIKSVEAVSAVNIYLEMDAIILKLLSPDMDESTKIHIFQDIERFENLIHLSDGKSNLI-ISSDLRRRIKEAIADGYQNVDRLRNCEIWMENYQLICQHNQSLYLSQYFESEFFLSTIYGERLSDIDTSYECEWEDINVTG 1394
            FM++ + + G+  F++ L    L+    FL + K  KQ+ D     +        D K ++ +P L L   +    + +   ++++L E+ ++++ N+I  WY  F+++E  + E++       A +L R  K+ +P L++ K L   + H++I    +       +    +Q+  L++    LH+A+ SR  E+ YL+++++ L+P + P   + TK+ +   L++E  SG+VLLP +D +ASPD +N  I L L  + +  ++    S  VP L ++     +    L+   K I   + ++ L+ F++++KS   V  +   L ++    KL+ PD+ ++    +  ++       +  DG  + I     +   +   +   Y +V RL+N     + Y+ +    ++++   +++S+ +   + GE       S   E + +N  G
Sbjct:   28 FMVFWSFLAGLATFYYALSPETLVPNLLFLISKKQKKQDPDGL--SRPIGCAVCGDVKCNRHRPTLSLESMQPWLDLKVPQKVDASLAELLELVLKNFIYPWYSDFTDDEALVDELRLTMRFAAAVLLRRTKKVDVPSLITDKLLKVAMKHIEIVVRAKQKVRNTDA----LQQAALEEYGPDLHLALRSRRSELRYLRTLTEMLLPQLIPHSTADTKSLML--LVREVVSGSVLLPLLDQLASPDFVNFLILLFLDETPMMDSM-EPSSPLVPFLEKFVQPRTKSFTVLKLELKEIR--KTQELLFLFMKFLKSQAVVHVLQFCLSVEDFNDKLIRPDLSDTEMQELHAEVCCLYR-TYCCDGSVDKIKFDPAVVAGLATVVHGPYADVVRLQNTPHLFQAYEHVLALLENVFTPMFWQSDEYFRYMIGE----ASPSATSELQQLNRRG 462
[Close]
BLAST of Sorting nexin-14 vs. Ensembl Nematostella
Match: EDO42608 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S0V2])

HSP 1 Score: 100.523 bits (249), Expect = 1.461e-21
Identity = 116/420 (27.62%), Postives = 168/420 (40.00%), Query Frame = 3 
Query: 1809 DLSYLRVKIPSISQPYVTNKKKGELYFSVYTYKV-DSDKLLYKVHRKYGEFYVLEQKLLEFH-------------GTIERALPPKRP------------WDNKNL----------------DFLEKCKLEFETYLMYLVNRTFLRNSELLHRFLTRPTEFS--FNSLIDINL-GKFVKSMPMIFTKEKGQFLDQFLYNFHISCEASSQAKSNSNNDPYSSLSNSVSDPGSKSLFDARLHTRMYWNNAELNTIKSENFMKDICSFSTRYIFYYFDSLCFFFEIITNKLAYSHFLLNFFYRIRSILVDVFQTYVKGVITRGFEKLCHEKLAVEIIHVLRDAALLSGLNRTISEKQERRNEALTSLYQLLPGWLSIVLSDDQIKTLYSNIDRIFDFLQQPKLNKQLSYVLFDILLLELFPELT 2933
            DLS  ++ IP +    +  K K     SV    V D     + V R+YGEFYVL  KL  FH             G  + +L    P             D+  L                 + E C+ +FE YL YL     L+ S LL+ FL+   EFS  F      NL GK  KS+  IFTKEKGQ LD FL  F  S E   + +      P  SLS    D G ++    R   + Y + +    + S+  +K+I +  T+           F  +    L                  D    Y  G +     + C + L V    +  D        RT ++K ERR + L  +   +P  +  ++   +    ++ +  + +  Q PKLNKQL+YVL D+LL E+FPEL+
Sbjct:  408 DLSTWKITIPHV---IMETKHKCIYIISVGRSIVTDGGDRRWDVARRYGEFYVLHSKLRAFHDATGVDYSQDKSEGPQDDSLGYTAPDCGYILFANPGAIDDTYLPPKKSSSKMSSVKKPATYYESCRQQFERYLQYLSGNPLLKGSALLYNFLSPEKEFSEMFGPSSVGNLAGKTFKSVTTIFTKEKGQNLDHFLSAFQASTEEPVKRRP-----PVRSLS---VDAGVQTNDFGRKEEQCYPDRSRSYGVSSDANVKNIDNSKTQLQLTGVTEYVMFVALAFGDLCGEG--------------DANDDYDDGGVDI---ESCGDNLVVGDDAIFFD----QDPPRTDADKIERREQTLIEMLDFIPEPVVRMMGGQR---HHNGMVLLLELFQHPKLNKQLAYVLLDVLLEEMFPELS 792
[Close]
BLAST of Sorting nexin-14 vs. Ensembl Medaka
Match: SNX14 (sorting nexin 14 [Source:NCBI gene;Acc:101169078])

HSP 1 Score: 238.81 bits (608), Expect = 4.636e-65
Identity = 224/924 (24.24%), Postives = 398/924 (43.07%), Query Frame = 3 
Query:  300 ALEEIFDIIIANYINSWYLGFSNNEDFIVEIKYFFHTLCAEILLRFSKISIPELVSQKFLPACINHLDICYTIQXXXXXXXXXLTPVQEILLQKMRSHLHVAMISRSEEVAYLKSISKFLIPLITPDYFSRTKNKISDHLLQECFSGTVLLPAMDSVASPDLINKFIYLLLTPSTISTALCNTQSSYVPILHRYQTAWMEKLKRLEEHPKGIECLRNEKHLYHFLQYIKSVEAVSAVNIYLEMDAIILKLLSPDMDESTKIHIFQDIERFENLIHLSDGKSNLIISSDLRRRIKEAIADGYQNVDRLRNCEIWMENYQLICQHNQSLYLSQYFES-EFFLSTIYGERLSDIDTSYECEWEDINVTGDSLNVVNPENLDNENLSRHESSPENFSFKKMSLDLFSFDFMSDRKSPIIEDQKSAFSTPDRVTXXXXXXXXXXXXXXXLSQIDKQKEFSMTKFGLSIKQVFTANSDD-----SLNLISGDLDI----------DNPDGSEWLSNSFGDL---------VDLPDLSYLRVKIPSISQPYVTNKKKGELYFSVYTYKVDSDKLLYKVHRKYGEFYVLEQKLLEFHGTIERA-LPPKRPWDNKNLDFLEKCKLEFETYLMYLVNRTFLRNSELLHRFLT---RPTEFSFNSLIDINLGKFVKSMPMIFTKEKGQFLDQFLYNFHISCEASSQAKSNSNNDPYSSLSNSVSDPGSKSLFDARLHTRMYWNNAELNTIK----SENFMKDICSFSTRYIFYYFDSLCFFFEIITNKLAYSHFLLNFFYRIRSILVDVFQTYVKGVITRGFEKLCHEKLAVEIIHVLRDAALLS-GLNRTISEKQERRNEALTSLYQLLPGWLSIVLSDDQIKTLYSNIDRIFDFLQQPKLNKQLSYVLFDILLLELFPELTDNVVAQNQNEVP 2969
            +L EI ++++ N++  WY   +++E F+ E++       A ++ R  K+ +  L++QK L   + H++I    +            +Q+  L++    LHVA+ SR +E+ YL+ +++ L P I P     T  +    L++E  +G+V LP+MD +A PD +N  I L +  S    A     S+ VP L +Y     +K   L+   K I     +  L+ F+ ++K   AV  +   L ++    ++L P++ ++ K+ + +++++      L +    +     +   I+      Y  V +L+      E Y+ +    + ++   +  S E+F   + G      ++     W+            +PE+L +   +   SSP +F+         +F +      P+     S  S+  R                        + F +++    IK VF + + +     S  L+ G+ D+          D+P  +    ++  +L         VD  D    R +IP        N +K           V  +   + V+R+Y EFYVLE KL EFHG+   A LP KR    KN +FL   + EF+ YL  L+    L NS+LL  FL+     ++F    L D+NLGK +K++P    KEKGQ L+ F+ ++  SCE+     S            ++  P S++  D +L   ++ NNA  +       ++N+  ++ +    Y     D L +   ++ +   + H LL      R +  +  + Y    +     ++  E   V +I +LRD         R+  +KQ R       +   +P  L   + +D     Y  +  +FD LQQP LNKQL+YVL DI + ELFPEL  N V +  + +P
Sbjct:  134 SLSEILELVLENFVYPWYREITDDEAFVDELRVTLRFFSAVLIRRIQKVDVASLITQKLLKVSMKHIEIISKARLKVKSTEH----LQQAALEEYGPDLHVALRSRRDELLYLRKLTEVLFPHILPP--KATDCRSLTLLIREVLAGSVFLPSMDYLADPDTVNHLILLFIDNSPPEEA-TEPSSTLVPFLQKYSDVRNKKPSVLKLELKEIR--EQQDLLFRFMNFLKQEGAVHVLQFCLTVEEFNDRILCPELSDTEKMMLHEEVKKIYETYCLEESIDKIRFDPFIVEEIRNVATGPYTQVVKLQTMRCLFEAYEHVLSLLEDVFTPMFCHSDEYFRQLLRGAESPARNSRMSSSWD-----------WSPESLSSPFTASGSSSPASFNSHHAQSTFTNFPY-----GPLSHRHSSPKSSSKR-----------------------GETFGISRISSKIKGVFKSTTMEGAMLPSHGLVEGEDDVVEEAMMVMEDDSPMEAASTPSTPRNLSAWSISIPYVDFYDDDVKRERIPVFCIDVERNDRKA----------VGHETEHWSVYRRYLEFYVLESKLTEFHGSFPDAQLPSKRIIGPKNYEFLTSKREEFQEYLQKLLQHPELSNSQLLADFLSPYSMESQFLDKMLPDVNLGKIIKAVPSKLIKEKGQHLEPFIQSYFNSCESPKPKPSRPEL--------TILSPTSEN--DKKLFNDVFKNNANRSETTDKRHNQNYFMEMITVEGVY-----DYLMYVGRVVFHIPDWLHHLL---MGGRILFKNTLEAYTDHYLQYKLNQVVQEHRLVSLITLLRDTVFCERSPPRSTQDKQSRAKRTFEEMMNYIPDVLGKCIGED---AKYEGVRLLFDCLQQPVLNKQLTYVLLDITIQELFPEL--NKVQKEASLLP 976
[Close]
BLAST of Sorting nexin-14 vs. Ensembl Medaka
Match: SNX14 (sorting nexin 14 [Source:NCBI gene;Acc:101169078])

HSP 1 Score: 238.424 bits (607), Expect = 6.180e-65
Identity = 223/918 (24.29%), Postives = 394/918 (42.92%), Query Frame = 3 
Query:  300 ALEEIFDIIIANYINSWYLGFSNNEDFIVEIKYFFHTLCAEILLRFSKISIPELVSQKFLPACINHLDICYTIQXXXXXXXXXLTPVQEILLQKMRSHLHVAMISRSEEVAYLKSISKFLIPLITPDYFSRTKNKISDHLLQECFSGTVLLPAMDSVASPDLINKFIYLLLTPSTISTALCNTQSSYVPILHRYQTAWMEKLKRLEEHPKGIECLRNEKHLYHFLQYIKSVEAVSAVNIYLEMDAIILKLLSPDMDESTKIHIFQDIERFENLIHLSDGKSNLIISSDLRRRIKEAIADGYQNVDRLRNCEIWMENYQLICQHNQSLYLSQYFES-EFFLSTIYGERLSDIDTSYECEWEDINVTGDSLNVVNPENLDNENLSRHESSPENFSFKKMSLDLFSFDFMSDRKSPIIEDQKSAFSTPDRVTXXXXXXXXXXXXXXXLSQIDKQKEFSMTKFGLSIKQVFTANSDD-----SLNLISGDLDI----------DNPDGSEWLSNSFGDL---------VDLPDLSYLRVKIPSISQPYVTNKKKGELYFSVYTYKVDSDKLLYKVHRKYGEFYVLEQKLLEFHGTIERA-LPPKRPWDNKNLDFLEKCKLEFETYLMYLVNRTFLRNSELLHRFLT---RPTEFSFNSLIDINLGKFVKSMPMIFTKEKGQFLDQFLYNFHISCEASSQAKSNSNNDPYSSLSNSVSDPGSKSLFDARLHTRMYWNNAELNTIK----SENFMKDICSFSTRYIFYYFDSLCFFFEIITNKLAYSHFLLNFFYRIRSILVDVFQTYVKGVITRGFEKLCHEKLAVEIIHVLRDAALLS-GLNRTISEKQERRNEALTSLYQLLPGWLSIVLSDDQIKTLYSNIDRIFDFLQQPKLNKQLSYVLFDILLLELFPELTDNVVAQ 2951
            +L EI ++++ N++  WY   +++E F+ E++       A ++ R  K+ +  L++QK L   + H++I    +            +Q+  L++    LHVA+ SR +E+ YL+ +++ L P I P     T  +    L++E  +G+V LP+MD +A PD +N  I L +  S    A     S+ VP L +Y     +K   L+   K I     +  L+ F+ ++K   AV  +   L ++    ++L P++ ++ K+ + +++++      L +    +     +   I+      Y  V +L+      E Y+ +    + ++   +  S E+F   + G      ++     W+            +PE+L +   +   SSP +F+         +F +      P+     S  S+  R                        + F +++    IK VF + + +     S  L+ G+ D+          D+P  +    ++  +L         VD  D    R +IP        N +K           V  +   + V+R+Y EFYVLE KL EFHG+   A LP KR    KN +FL   + EF+ YL  L+    L NS+LL  FL+     ++F    L D+NLGK +K++P    KEKGQ L+ F+ ++  SCE+     S            ++  P S++  D +L   ++ NNA  +       ++N+  ++ +    Y     D L +   ++ +   + H LL      R +  +  + Y    +     ++  E   V +I +LRD         R+  +KQ R       +   +P  L   + +D     Y  +  +FD LQQP LNKQL+YVL DI + ELFPEL    V Q
Sbjct:  134 SLSEILELVLENFVYPWYREITDDEAFVDELRVTLRFFSAVLIRRIQKVDVASLITQKLLKVSMKHIEIISKARLKVKSTEH----LQQAALEEYGPDLHVALRSRRDELLYLRKLTEVLFPHILPP--KATDCRSLTLLIREVLAGSVFLPSMDYLADPDTVNHLILLFIDNSPPEEA-TEPSSTLVPFLQKYSDVRNKKPSVLKLELKEIR--EQQDLLFRFMNFLKQEGAVHVLQFCLTVEEFNDRILCPELSDTEKMMLHEEVKKIYETYCLEESIDKIRFDPFIVEEIRNVATGPYTQVVKLQTMRCLFEAYEHVLSLLEDVFTPMFCHSDEYFRQLLRGAESPARNSRMSSSWD-----------WSPESLSSPFTASGSSSPASFNSHHAQSTFTNFPY-----GPLSHRHSSPKSSSKR-----------------------GETFGISRISSKIKGVFKSTTMEGAMLPSHGLVEGEDDVVEEAMMVMEDDSPMEAASTPSTPRNLSAWSISIPYVDFYDDDVKRERIPVFCIDVERNDRKA----------VGHETEHWSVYRRYLEFYVLESKLTEFHGSFPDAQLPSKRIIGPKNYEFLTSKREEFQEYLQKLLQHPELSNSQLLADFLSPYSMESQFLDKMLPDVNLGKIIKAVPSKLIKEKGQHLEPFIQSYFNSCESPKPKPSRPEL--------TILSPTSEN--DKKLFNDVFKNNANRSETTDKRHNQNYFMEMITVEGVY-----DYLMYVGRVVFHIPDWLHHLL---MGGRILFKNTLEAYTDHYLQYKLNQVVQEHRLVSLITLLRDTVFCERSPPRSTQDKQSRAKRTFEEMMNYIPDVLGKCIGED---AKYEGVRLLFDCLQQPVLNKQLTYVLLDITIQELFPELNKVKVFQ 972
[Close]
BLAST of Sorting nexin-14 vs. Ensembl Medaka
Match: SNX14 (sorting nexin 14 [Source:NCBI gene;Acc:101169078])

HSP 1 Score: 207.223 bits (526), Expect = 1.472e-54
Identity = 210/917 (22.90%), Postives = 381/917 (41.55%), Query Frame = 3 
Query:  300 ALEEIFDIIIANYINSWYLGFSNNEDFIVEIKYFFHTLCAEILLRFSKISIPELVSQKFLPACINHLDICYTIQXXXXXXXXXLTPVQEILLQKMRSHLHVAMISRSEEVAYLKSISKFLIPLITPDYFSRTKNKISDHLLQECFSGTVLLPAMDSVASPDLINKFIYLLLTPSTISTALCNTQSSYVPILHRYQTAWMEKLKRLEEHPKGIECLRNEKHLYHFLQYIKSVEAVSAVNIYLEMDAIILKLLSPDMDESTKIHIFQDIERFENLIHLSDGKSNLIISSDLRRRIKEAIADGYQNVDRLRNCEIWMENYQLICQHNQSLYLSQYFES-EFFLSTIYGERLSDIDTSYECEWEDINVTGDSLNVVNPENLDNENLSRHESSPENFSFKKMSLDLFSFDFMSDRKSPIIEDQKSAFSTPDRVTXXXXXXXXXXXXXXXLSQIDKQKEFSMTKFGLSIKQVFTANSDD-----SLNLISGDLDI----------DNPDGSEWLSNSFGDL---------VDLPDLSYLRVKIPSISQPYVTNKKKGELYFSVYTYKVDSDKLLYKVHRKYGEFYVLEQKLLEFHGTIERA-LPPKRPWDNKNLDFLEKCKLEFETYLMYLVNRTFLRNSELLHRFL---TRPTEFSFNSLIDINLGKFVKSMPMIFTKEKGQFLDQFLYNFHISCEASSQAKSNSNNDPYSSLSNSVSDPGSKSLFDARLHTRMYWNNAELNTIK----SENFMKDICSFSTRYIFYYFDSLCFFFEIITNKLAYSHFLLNFFYRIRSILVDVFQTYVKGVITRGFEKLCHEKLAVEIIHVLRDAALLS-GLNRTISEKQERRNEALTSLYQLLPG---WLSIVLSDDQIKTLYSN------------------IDRIFDFLQQPKLNKQLS 2885
            +L EI ++++ N++  WY   +++E F+ E++       A ++ R  K+ +  L++QK L   + H++I    +            +Q+  L++    LHVA+ SR +E+ YL+ +++ L P I P     T  +    L++E  +G+V LP+MD +A PD +N  I L +  S    A     S+ VP L +Y     +K   L+   K I     +  L+ F+ ++K   AV  +   L ++    ++L P++ ++ K+ + +++++      L +    +     +   I+      Y  V +L+      E Y+ +    + ++   +  S E+F   + G      ++     W+            +PE+L +   +   SSP +F+         +F +      P+     S  S+  R                        + F +++    IK VF + + +     S  L+ G+ D+          D+P  +    ++  +L         VD  D    R +IP        N +K           V  +   + V+R+Y EFYVLE KL EFHG+   A LP KR    KN +FL   + EF+ YL  L+    L NS+LL  FL   +  ++F    L D+NLGK +K++P    KEKGQ L+ F+ ++  SCE+     S            ++  P S++  D +L   ++ NNA  +       ++N+  ++ +    Y     D L +   ++ +   + H LL      R +  +  + Y    +     ++  E   V +I +LRD         R+  +KQ R       +   +PG    +S   +   +   Y N                  +  +FD LQQP LNKQ+ 
Sbjct:  134 SLSEILELVLENFVYPWYREITDDEAFVDELRVTLRFFSAVLIRRIQKVDVASLITQKLLKVSMKHIEIISKARLKVKSTEH----LQQAALEEYGPDLHVALRSRRDELLYLRKLTEVLFPHILPP--KATDCRSLTLLIREVLAGSVFLPSMDYLADPDTVNHLILLFIDNSPPEEA-TEPSSTLVPFLQKYSDVRNKKPSVLKLELKEIR--EQQDLLFRFMNFLKQEGAVHVLQFCLTVEEFNDRILCPELSDTEKMMLHEEVKKIYETYCLEESIDKIRFDPFIVEEIRNVATGPYTQVVKLQTMRCLFEAYEHVLSLLEDVFTPMFCHSDEYFRQLLRGAESPARNSRMSSSWD-----------WSPESLSSPFTASGSSSPASFNSHHAQSTFTNFPY-----GPLSHRHSSPKSSSKR-----------------------GETFGISRISSKIKGVFKSTTMEGAMLPSHGLVEGEDDVVEEAMMVMEDDSPMEAASTPSTPRNLSAWSISIPYVDFYDDDVKRERIPVFCIDVERNDRKA----------VGHETEHWSVYRRYLEFYVLESKLTEFHGSFPDAQLPSKRIIGPKNYEFLTSKREEFQEYLQKLLQHPELSNSQLLADFLSPYSMESQFLDKMLPDVNLGKIIKAVPSKLIKEKGQHLEPFIQSYFNSCESPKPKPSRPE--------LTILSPTSEN--DKKLFNDVFKNNANRSETTDKRHNQNYFMEMITVEGVY-----DYLMYVGRVVFHIPDWLHHLL---MGGRILFKNTLEAYTDHYLQYKLNQVVQEHRLVSLITLLRDTVFCERSPPRSTQDKQSRAKRTFEEMMNYIPGIHPAVSCRFAPSHLHVKYGNSSTDVLGKCIGEDAKYEGVRLLFDCLQQPVLNKQVG 974
[Close]
BLAST of Sorting nexin-14 vs. Ensembl Medaka
Match: ENSORLT00000011515.2 (sorting nexin-14 [Source:NCBI gene;Acc:101169255])

HSP 1 Score: 164.851 bits (416), Expect = 3.769e-41
Identity = 137/443 (30.93%), Postives = 208/443 (46.95%), Query Frame = 3 
Query: 1644 KQKEFSMTKFGLSIKQVFTANSDDSLNLISGDLDIDNPDGSEWLSNSFGDLVDLP----DLSYLRVKIPSISQPYVTNKKKGELYFSVYTYK-----VDSDKLLYKVHRKYGEFYVLEQKLLEFHGTIERA-LPPKRPWDNKNLDFLEKCKLEFETYLMYLVNRTFLRNSELLHRFLT---RPTEFSFNSLIDINLGKFVKSMPMIFTKEKGQFLDQFLYNFHISCEASSQAKSNSNNDPYSSLSNSVSDPGSKSLFDARLHTRMYWNNAELNTIKSENFMKDICSFSTRYIFYYFDSLCFFFEIITNKLAYSHFLLNFFYRIRSILVDVFQTYVKGVITRGFEKLCHEKLAVEIIHVLRDAALL-SGLNRTISEKQERRNEALTSLYQLLPGWLSIVLSDDQIKTLYSNIDRIFDFLQQPKLNKQLSYVLFDILLLELFPEL 2930
            + + F+M K    +K VF + + +   L   + D+     + +   S  ++   P    +LS  RV IP I       K++    F +   +     V  D   + V R+Y EFYVLE KL EFHGT   A LP KR    KN +FL+  + EFE YL  L+    L NS+LL  FL+     ++F    L D+NLGK  KS+P    KEKGQ L+ F+ +F  SCE+    K   +    + LS +      K LF A     +Y NN +L      N   + C      +   +D +     ++     + H LL      R +L +  + Y+   +    +++  E   V +I  LRDA    SG  RT  ++Q R  +    + + LP ++   + ++     +  +  +FD LQQP LNKQ++YVL DI +LELFPEL
Sbjct:  486 RGESFNMRKLSSKLKDVFRSTTMEGAMLPPSEEDVVEEAAAVYEDESSSEVAAAPGIQRNLSAWRVSIPFIDFCEDEVKREKIPVFCIDVERNDRKDVGHDTEKWFVPRRYLEFYVLESKLTEFHGTFADAQLPSKRIIGPKNYEFLQSKREEFEEYLQNLLKHPELSNSQLLADFLSPFSMESQFLEKMLPDVNLGKIFKSVPGKLMKEKGQNLEPFIQSFFNSCESP---KPKPSRPELTILSPTAEI--KKKLFSA-----LYQNNMDLQEDAVRNHRSN-CFLEMMTVHGMYDYMMHVARVVFRIPDWLHHLLAAG---RILLKNTLEAYMDQYMQSKLDQVLQEHRMVSLITQLRDAVFCESGEKRTAEDRQARAKQTFQEMIRYLPDFVGKCIGEE---AKHDGVRLLFDALQQPLLNKQMAYVLLDIAVLELFPEL 911

HSP 2 Score: 111.694 bits (278), Expect = 1.387e-24
Identity = 79/345 (22.90%), Postives = 161/345 (46.67%), Query Frame = 3 
Query:  300 ALEEIFDIIIANYINSWYLGFSNNEDFIVEIKYFFHTLCAEILLRFSKISIPELVSQKFLPACINHLDICYTIQXXXXXXXXXLTPVQEILLQKMRSHLHVAMISRSEEVAYLKSISKFLIPLITPDYFSRTKNKISDHLLQECFSGTVLLPAMDSVASPDLINKFIYLLLTPSTISTALCNTQSSYVPILHRYQTAWMEKLKRLEEHPKGIECLRNEKHLYHFLQYIKSVEAVSAVNIYLEMDAIILKLLSPDMDESTKIHIFQDIERFENLIHLSDGKSNLIISSDLRRRIKEAIADGYQNVDRLRNCEIWMENYQLICQHNQSLYLSQYFES-EFFLSTIYG 1331
            ++ E+F++++ N++  WY   +++E  + E++  F  L + ++ R  K+ IP + + K + A + H++I    Q  +    +    ++   L++    LH A+ SR  E+ YL+ +++ L+P + P     T  +    LL+E  SG+V+LP MD +A PD +N  + + +  S    A     S  VP L +Y     +K   L+   K I     +  L+ FL ++K   AV  +   L ++    K+LSP++ +     +  ++        L +    +   + +   I+   +  Y +V RL+      E Y+ +    ++++   +  S E+F   + G
Sbjct:  134 SIAEVFELVLENFVYPWYREITDDEASLDEVRMTFRFLASVLVRRAQKVDIPGVFADKVMKAAMKHIEIIAKAQEKAKNADA----LERAALEEYGPGLHAALYSRKNELLYLRKLTEMLLPYVLPP--KATDCRSLALLLREVMSGSVILPTMDFMADPDTVNLMVLIFVDHSPPEPA-TEPPSPLVPFLQKYANGSTKKSSVLKLELKDIR--EQQDLLFRFLNFLKQEGAVHVLQFCLAVEEFNDKILSPELSDGELRRLHGEVLHIYETYCLDESVDKISFDASIVEEIRNIASAPYSDVVRLQKTTCLFEAYEHVLSLLETVFTPMFCHSDEYFRHLLRG 469
[Close]
BLAST of Sorting nexin-14 vs. Ensembl Medaka
Match: ENSORLT00000047061.1 (sorting nexin-14 [Source:NCBI gene;Acc:101169255])

HSP 1 Score: 137.887 bits (346), Expect = 3.848e-34
Identity = 127/435 (29.20%), Postives = 198/435 (45.52%), Query Frame = 3 
Query: 1629 LSQIDKQKEFSMTKFGLSIKQVFTANSDDSLNLISGDLDIDNPD--GSEWLSNSFGDLVDLP----DLSYLRVKIPSISQPYVTNKKKGELYFSVYTYK-----VDSDKLLYKVHRKYGEFYVLEQKLLEFHGTIERA-LPPKRPWDNKNLDFLEKCKLEFETYLMYLVNRTFLRNSELLHRFLT---RPTEFSFNSLIDINLGKFVKSMPMIFTKEKGQFLDQFLYNFHISCEASSQAKSNSNNDPYSSLSNSVSDPGSKSLFDARLHTRMYWNNAELNTIKSENFMKDICSFSTRYIFYYFDSLCFFFEIITNKLAYSHFLLNFFYRIRSILVDVFQTYVKGVITRGFEKLCHEKLAVEIIHVLRDAALL-SGLNRTISEKQERRNEALTSLYQLLPGWLSIVLSDDQIKTLYSNIDRIFDFLQQPKLNKQLS 2885
            L  I + + F+M K    +K VF + + +   L   + D+   +   + +   S  ++   P    +LS  RV IP I       K++    F +   +     V  D   + V R+Y EFYVLE KL EFHGT   A LP KR    KN +FL+  + EFE YL  L+    L NS+LL  FL+     ++F    L D+NLGK  KS+P    KEKGQ L+ F+ +F  SCE+    K   +    + LS +      K LF A     +Y NN +L      N   + C      +   +D +     ++     + H LL      R +L +  + Y+   +    +++  E   V +I  LRDA    SG  RT  ++Q R  +    + + LP ++   + ++     +  +  +FD LQQP LNKQ++
Sbjct:    6 LCLISRGESFNMRKLSSKLKDVFRSTTMEGAMLPPSEEDVVRVEEAAAVYEDESSSEVAAAPGIQRNLSAWRVSIPFIDFCEDEVKREKIPVFCIDVERNDRKDVGHDTEKWFVPRRYLEFYVLESKLTEFHGTFADAQLPSKRIIGPKNYEFLQSKREEFEEYLQNLLKHPELSNSQLLADFLSPFSMESQFLEKMLPDVNLGKIFKSVPGKLMKEKGQNLEPFIQSFFNSCES---PKPKPSRPELTILSPTAEI--KKKLFSA-----LYQNNMDLQEDAVRNHRSN-CFLEMMTVHGMYDYMMHVARVVFRIPDWLHHLLA---AGRILLKNTLEAYMDQYMQSKLDQVLQEHRMVSLITQLRDAVFCESGEKRTAEDRQARAKQTFQEMIRYLPDFVGKCIGEE---AKHDGVRLLFDALQQPLLNKQVN 423
[Close]
BLAST of Sorting nexin-14 vs. Planmine SMEST
Match: SMESG000057128.1 (SMESG000057128.1)

HSP 1 Score: 1825.06 bits (4726), Expect = 0.000e+0
Identity = 932/939 (99.25%), Postives = 935/939 (99.57%), Query Frame = 3 
Query:  162 KQEEDFYLKFKNFRFFSLNDFKNSKKKPNLYLVENKXXXXXXXXXXALEEIFDIIIANYINSWYLGFSNNEDFIVEIKYFFHTLCAEILLRFSKISIPELVSQKFLPACINHLDICYTIQXXXXXXXXXLTPVQEILLQKMRSHLHVAMISRSEEVAYLKSISKFLIPLITPDYFSRTKNKISDHLLQECFSGTVLLPAMDSVASPDLINKFIYLLLTPSTISTALCNTQSSYVPILHRYQTAWMEKLKRLEEHPKGIECLRNEKHLYHFLQYIKSVEAVSAVNIYLEMDAIILKLLSPDMDESTKIHIFQDIERFENLIHLSDGKSNLIISSDLRRRIKEAIADGYQNVDRLRNCEIWMENYQLICQHNQSLYLSQYFESEFFLSTIYGERLSDIDTSYECEWEDINVTGDSLNVVNPENLDNENLSRHESSPENFSFKKMSLDLFSFDFMSDRKSPIIEDQKSAFSTPDRVTXXXXXXXXXXXXXXXLSQIDKQKEFSMTKFGLSIKQVFTANSDDSLNLISGDLDIDNPDGSEWLSNSFGDLVDLPDLSYLRVKIPSISQPYVTNKKKGELYFSVYTYKVDSDKLLYKVHRKYGEFYVLEQKLLEFHGTIERALPPKRPWDNKNLDFLEKCKLEFETYLMYLVNRTFLRNSELLHRFLTRPTEFSFNSLIDINLGKFVKSMPMIFTKEKGQFLDQFLYNFHISCEASSQAKSNSNNDPYSSLSNSVSDPGSKSLFDARLHTRMYWNNAELNTIKSENFMKDICSFSTRYIFYYFDSLCFFFEIITNKLAYSHFLLNFFYRIRSILVDVFQTYVKGVITRGFEKLCHEKLAVEIIHVLRDAALLSGLNRTISEKQERRNEALTSLYQLLPGWLSIVLSDDQIKTLYSNIDRIFDFLQQPKLNKQLSYVLFDILLLELFPELTDNVVAQNQNEVPTKN 2978
            +QEEDFYLKFKNFRF SLNDFKNSKKKPNLYLVENKSIFINSNINSALEEIFDIIIANYINSWYLGFSNNEDFIVEIKYFFHTLCAEILLRFSKISIPELVSQKFLPACINHLDICYTIQSS+NENSSSLTPVQEILLQKMRSHLHVAMISR+EEVAYLKSISKFLIPLITPDYFSRTKNKISDHLLQECFSGTVLLPAMDSVASPDLINKFIYLLLTPSTISTALCNTQSSYVPILHRYQTAWMEKLKRLEEHPKGIECLRNEKHLYHFLQYIKSVEAVSAVNIYLEMDAIILKLLSPDMDESTKIHIFQDIERFENLIHLSDGKSNLIISSDLRRRIKEAIADGYQNVDRLRNCEIWMENYQLICQH QSLYLSQYFESEFFLSTIYGERLSDIDTSYECEWEDINVTGDSLNVVNPENLDNENLSRHESSPENFSFKKMSLDLFSFDFMSDRKSPIIEDQKSAFSTPDRVTAPAFPFFQFFQKEKELSQIDKQKEFSMTKFGLSIKQ FTANSDDSLN ISGDLDIDNPDGSEWLSNSFGDLVDLPDLSYLRVKIPSISQPYVTNKKKGELYFSVYTYKVDSDKLLYKVHRKYGEFYVLEQKLLEFHGTIERALPPKRPWDNKNLDFLEKCKLEFETYLMYLVNRTFLRNSELLHRFLTRPTEFSFNSLIDINLGKFVKSMPMIFTKEKGQFLDQFLYNFHISCEASSQAKSNSNNDPYSSLSNSVSDPGSKSLFDARLHTRMYWNNAELNTIKSENFMKDICSFSTRYIFYYFDSLCFFFEIITNKLAYSHFLLNFFYRIRSILVDVFQTYVKGVITRGFEKLCHEKLAVEIIHVLRDAALLSGLNRTISEKQERRNEALTSLYQLLPGWLSIVLSDDQIKTLYSNIDRIFDFLQQPKLNKQLSYVLFDILLLELFPELTDNVVAQNQNEVPTKN
Sbjct:   18 RQEEDFYLKFKNFRFLSLNDFKNSKKKPNLYLVENKSIFINSNINSALEEIFDIIIANYINSWYLGFSNNEDFIVEIKYFFHTLCAEILLRFSKISIPELVSQKFLPACINHLDICYTIQSSNNENSSSLTPVQEILLQKMRSHLHVAMISRAEEVAYLKSISKFLIPLITPDYFSRTKNKISDHLLQECFSGTVLLPAMDSVASPDLINKFIYLLLTPSTISTALCNTQSSYVPILHRYQTAWMEKLKRLEEHPKGIECLRNEKHLYHFLQYIKSVEAVSAVNIYLEMDAIILKLLSPDMDESTKIHIFQDIERFENLIHLSDGKSNLIISSDLRRRIKEAIADGYQNVDRLRNCEIWMENYQLICQHTQSLYLSQYFESEFFLSTIYGERLSDIDTSYECEWEDINVTGDSLNVVNPENLDNENLSRHESSPENFSFKKMSLDLFSFDFMSDRKSPIIEDQKSAFSTPDRVTAPAFPFFQFFQKEKELSQIDKQKEFSMTKFGLSIKQAFTANSDDSLNSISGDLDIDNPDGSEWLSNSFGDLVDLPDLSYLRVKIPSISQPYVTNKKKGELYFSVYTYKVDSDKLLYKVHRKYGEFYVLEQKLLEFHGTIERALPPKRPWDNKNLDFLEKCKLEFETYLMYLVNRTFLRNSELLHRFLTRPTEFSFNSLIDINLGKFVKSMPMIFTKEKGQFLDQFLYNFHISCEASSQAKSNSNNDPYSSLSNSVSDPGSKSLFDARLHTRMYWNNAELNTIKSENFMKDICSFSTRYIFYYFDSLCFFFEIITNKLAYSHFLLNFFYRIRSILVDVFQTYVKGVITRGFEKLCHEKLAVEIIHVLRDAALLSGLNRTISEKQERRNEALTSLYQLLPGWLSIVLSDDQIKTLYSNIDRIFDFLQQPKLNKQLSYVLFDILLLELFPELTDNVVAQNQNEVPTKN 956
[Close]
BLAST of Sorting nexin-14 vs. Planmine SMEST
Match: SMESG000057128.1 (SMESG000057128.1)

HSP 1 Score: 910.983 bits (2353), Expect = 0.000e+0
Identity = 444/446 (99.55%), Postives = 444/446 (99.55%), Query Frame = 3 
Query: 1641 DKQKEFSMTKFGLSIKQVFTANSDDSLNLISGDLDIDNPDGSEWLSNSFGDLVDLPDLSYLRVKIPSISQPYVTNKKKGELYFSVYTYKVDSDKLLYKVHRKYGEFYVLEQKLLEFHGTIERALPPKRPWDNKNLDFLEKCKLEFETYLMYLVNRTFLRNSELLHRFLTRPTEFSFNSLIDINLGKFVKSMPMIFTKEKGQFLDQFLYNFHISCEASSQAKSNSNNDPYSSLSNSVSDPGSKSLFDARLHTRMYWNNAELNTIKSENFMKDICSFSTRYIFYYFDSLCFFFEIITNKLAYSHFLLNFFYRIRSILVDVFQTYVKGVITRGFEKLCHEKLAVEIIHVLRDAALLSGLNRTISEKQERRNEALTSLYQLLPGWLSIVLSDDQIKTLYSNIDRIFDFLQQPKLNKQLSYVLFDILLLELFPELTDNVVAQNQNEVPTKN 2978
            DKQKEFSMTKFGLSIKQ FTANSDDSLN ISGDLDIDNPDGSEWLSNSFGDLVDLPDLSYLRVKIPSISQPYVTNKKKGELYFSVYTYKVDSDKLLYKVHRKYGEFYVLEQKLLEFHGTIERALPPKRPWDNKNLDFLEKCKLEFETYLMYLVNRTFLRNSELLHRFLTRPTEFSFNSLIDINLGKFVKSMPMIFTKEKGQFLDQFLYNFHISCEASSQAKSNSNNDPYSSLSNSVSDPGSKSLFDARLHTRMYWNNAELNTIKSENFMKDICSFSTRYIFYYFDSLCFFFEIITNKLAYSHFLLNFFYRIRSILVDVFQTYVKGVITRGFEKLCHEKLAVEIIHVLRDAALLSGLNRTISEKQERRNEALTSLYQLLPGWLSIVLSDDQIKTLYSNIDRIFDFLQQPKLNKQLSYVLFDILLLELFPELTDNVVAQNQNEVPTKN
Sbjct:  417 DKQKEFSMTKFGLSIKQAFTANSDDSLNSISGDLDIDNPDGSEWLSNSFGDLVDLPDLSYLRVKIPSISQPYVTNKKKGELYFSVYTYKVDSDKLLYKVHRKYGEFYVLEQKLLEFHGTIERALPPKRPWDNKNLDFLEKCKLEFETYLMYLVNRTFLRNSELLHRFLTRPTEFSFNSLIDINLGKFVKSMPMIFTKEKGQFLDQFLYNFHISCEASSQAKSNSNNDPYSSLSNSVSDPGSKSLFDARLHTRMYWNNAELNTIKSENFMKDICSFSTRYIFYYFDSLCFFFEIITNKLAYSHFLLNFFYRIRSILVDVFQTYVKGVITRGFEKLCHEKLAVEIIHVLRDAALLSGLNRTISEKQERRNEALTSLYQLLPGWLSIVLSDDQIKTLYSNIDRIFDFLQQPKLNKQLSYVLFDILLLELFPELTDNVVAQNQNEVPTKN 862

HSP 2 Score: 765.763 bits (1976), Expect = 0.000e+0
Identity = 394/399 (98.75%), Postives = 397/399 (99.50%), Query Frame = 3 
Query:  162 KQEEDFYLKFKNFRFFSLNDFKNSKKKPNLYLVENKXXXXXXXXXXALEEIFDIIIANYINSWYLGFSNNEDFIVEIKYFFHTLCAEILLRFSKISIPELVSQKFLPACINHLDICYTIQXXXXXXXXXLTPVQEILLQKMRSHLHVAMISRSEEVAYLKSISKFLIPLITPDYFSRTKNKISDHLLQECFSGTVLLPAMDSVASPDLINKFIYLLLTPSTISTALCNTQSSYVPILHRYQTAWMEKLKRLEEHPKGIECLRNEKHLYHFLQYIKSVEAVSAVNIYLEMDAIILKLLSPDMDESTKIHIFQDIERFENLIHLSDGKSNLIISSDLRRRIKEAIADGYQNVDRLRNCEIWMENYQLICQHNQSLYLSQYFESEFFLSTIYGERLSDIDTS 1358
            +QEEDFYLKFKNFRF SLNDFKNSKKKPNLYLVENKSIFINSNINSALEEIFDIIIANYINSWYLGFSNNEDFIVEIKYFFHTLCAEILLRFSKISIPELVSQKFLPACINHLDICYTIQSS+NENSSSLTPVQEILLQKMRSHLHVAMISR+EEVAYLKSISKFLIPLITPDYFSRTKNKISDHLLQECFSGTVLLPAMDSVASPDLINKFIYLLLTPSTISTALCNTQSSYVPILHRYQTAWMEKLKRLEEHPKGIECLRNEKHLYHFLQYIKSVEAVSAVNIYLEMDAIILKLLSPDMDESTKIHIFQDIERFENLIHLSDGKSNLIISSDLRRRIKEAIADGYQNVDRLRNCEIWMENYQLICQH QSLYLSQYFESEFFLSTIYGERLSDIDTS
Sbjct:   18 RQEEDFYLKFKNFRFLSLNDFKNSKKKPNLYLVENKSIFINSNINSALEEIFDIIIANYINSWYLGFSNNEDFIVEIKYFFHTLCAEILLRFSKISIPELVSQKFLPACINHLDICYTIQSSNNENSSSLTPVQEILLQKMRSHLHVAMISRAEEVAYLKSISKFLIPLITPDYFSRTKNKISDHLLQECFSGTVLLPAMDSVASPDLINKFIYLLLTPSTISTALCNTQSSYVPILHRYQTAWMEKLKRLEEHPKGIECLRNEKHLYHFLQYIKSVEAVSAVNIYLEMDAIILKLLSPDMDESTKIHIFQDIERFENLIHLSDGKSNLIISSDLRRRIKEAIADGYQNVDRLRNCEIWMENYQLICQHTQSLYLSQYFESEFFLSTIYGERLSDIDTS 416
The following BLAST results are available for this feature:
BLAST of Sorting nexin-14 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
SNX149.128e-3730.13sorting nexin 14 [Source:HGNC Symbol;Acc:HGNC:1497... [more]
SNX141.253e-3630.13sorting nexin 14 [Source:HGNC Symbol;Acc:HGNC:1497... [more]
SNX141.309e-3630.13sorting nexin 14 [Source:HGNC Symbol;Acc:HGNC:1497... [more]
SNX141.359e-3630.13sorting nexin 14 [Source:HGNC Symbol;Acc:HGNC:1497... [more]
SNX141.587e-2928.57sorting nexin 14 [Source:HGNC Symbol;Acc:HGNC:1497... [more]
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BLAST of Sorting nexin-14 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 2
Match NameE-valueIdentityDescription
snx-142.267e-2130.70Sorting NeXin [Source:UniProtKB/TrEMBL;Acc:G5EF63... [more]
snx-142.267e-2130.70Sorting NeXin [Source:UniProtKB/TrEMBL;Acc:G5EF63... [more]
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BLAST of Sorting nexin-14 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Sorting nexin-14 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 4
Match NameE-valueIdentityDescription
snx142.792e-3929.98sorting nexin 14 [Source:NCBI gene;Acc:555970][more]
snx145.204e-3929.98sorting nexin 14 [Source:NCBI gene;Acc:555970][more]
snx141.905e-1132.43sorting nexin 14 [Source:NCBI gene;Acc:555970][more]
snx133.919e-622.54sorting nexin 13 [Source:ZFIN;Acc:ZDB-GENE-050306-... [more]
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BLAST of Sorting nexin-14 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
mettl2b3.356e-3834.88methyltransferase like 2B [Source:Xenbase;Acc:XB-G... [more]
mettl2b8.919e-3233.03methyltransferase like 2B [Source:Xenbase;Acc:XB-G... [more]
mettl2b1.133e-3032.72methyltransferase like 2B [Source:Xenbase;Acc:XB-G... [more]
mettl2b2.355e-3032.82methyltransferase like 2B [Source:Xenbase;Acc:XB-G... [more]
mettl2b2.588e-3032.82methyltransferase like 2B [Source:Xenbase;Acc:XB-G... [more]
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BLAST of Sorting nexin-14 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 4
Match NameE-valueIdentityDescription
Snx149.643e-3730.13sorting nexin 14 [Source:MGI Symbol;Acc:MGI:215566... [more]
Snx149.710e-3730.13sorting nexin 14 [Source:MGI Symbol;Acc:MGI:215566... [more]
Snx141.146e-3634.40sorting nexin 14 [Source:MGI Symbol;Acc:MGI:215566... [more]
Snx142.043e-2223.33sorting nexin 14 [Source:MGI Symbol;Acc:MGI:215566... [more]
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BLAST of Sorting nexin-14 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 4
Match NameE-valueIdentityDescription
sp|Q5PNP1|SNX14_DANRE3.928e-3829.98Sorting nexin-14 OS=Danio rerio OX=7955 GN=snx14 P... [more]
sp|Q5R903|SNX14_PONAB1.870e-3630.35Sorting nexin-14 OS=Pongo abelii OX=9601 GN=SNX14 ... [more]
sp|Q9Y5W7|SNX14_HUMAN6.528e-3630.13Sorting nexin-14 OS=Homo sapiens OX=9606 GN=SNX14 ... [more]
sp|Q8BHY8|SNX14_MOUSE6.792e-3630.13Sorting nexin-14 OS=Mus musculus OX=10090 GN=Snx14... [more]
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BLAST of Sorting nexin-14 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A1A8IGD52.976e-6524.51Sorting nexin 14 OS=Nothobranchius kuhntae OX=3214... [more]
A0A1A8MLA24.597e-6524.40Sorting nexin 14 OS=Nothobranchius pienaari OX=704... [more]
A0A1A8QX886.046e-6524.51Sorting nexin 14 OS=Nothobranchius rachovii OX=451... [more]
A0A3Q1IQY01.472e-6424.65Sorting nexin 14 OS=Anabas testudineus OX=64144 GN... [more]
A0A1A8DC692.641e-6424.59Sorting nexin 14 OS=Nothobranchius kadleci OX=1051... [more]
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BLAST of Sorting nexin-14 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
SNX142.399e-6425.83sorting nexin 14 [Source:NCBI gene;Acc:103025420][more]
SNX146.304e-6425.50sorting nexin 14 [Source:NCBI gene;Acc:103025420][more]
SNX143.574e-3630.33sorting nexin 14 [Source:NCBI gene;Acc:103025420][more]
SNX144.278e-3630.33sorting nexin 14 [Source:NCBI gene;Acc:103025420][more]
SNX144.453e-3630.33sorting nexin 14 [Source:NCBI gene;Acc:103025420][more]
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BLAST of Sorting nexin-14 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1
Match NameE-valueIdentityDescription
snx141.919e-3431.38sorting nexin 14 [Source:NCBI gene;Acc:555970][more]
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BLAST of Sorting nexin-14 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Sorting nexin-14 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1
Match NameE-valueIdentityDescription
EDO426081.461e-2127.62Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Sorting nexin-14 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
SNX144.636e-6524.24sorting nexin 14 [Source:NCBI gene;Acc:101169078][more]
SNX146.180e-6524.29sorting nexin 14 [Source:NCBI gene;Acc:101169078][more]
SNX141.472e-5422.90sorting nexin 14 [Source:NCBI gene;Acc:101169078][more]
ENSORLT00000011515.23.769e-4130.93sorting nexin-14 [Source:NCBI gene;Acc:101169255][more]
ENSORLT00000047061.13.848e-3429.20sorting nexin-14 [Source:NCBI gene;Acc:101169255][more]
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BLAST of Sorting nexin-14 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 2
Match NameE-valueIdentityDescription
SMESG000057128.10.000e+099.25SMESG000057128.1[more]
SMESG000057128.10.000e+099.55SMESG000057128.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30008612 ID=SMED30008612|Name=Sorting nexin-14|organism=Schmidtea mediterranea sexual|type=transcript|length=3035bp
TTCCGATCTTATTTTTCTACTATTTAGATTATAATTATTAGTAAACTTAA
TTAGTTTATTATTATTAATTAAATTTTATGATTTATCTTGCAATAATATA
TGGAATATTTTTTTTTCTTCTGGGATATTTAATAAAATTTTTACAAACTC
CTAAGAATGTTAAGCAGGAAGAAGATTTTTATTTAAAATTTAAGAATTTC
AGATTTTTTAGTTTAAATGATTTTAAAAATTCGAAAAAAAAACCGAATTT
GTATCTAGTGGAAAATAAATCTATTTTCATTAATTCTAATATCAATTCTG
CATTGGAAGAAATCTTTGATATAATAATTGCAAATTATATCAACAGCTGG
TATCTTGGGTTTTCAAACAACGAAGATTTTATTGTGGAAATCAAATATTT
CTTTCATACTTTATGCGCAGAAATTCTTTTAAGATTTTCAAAGATTAGTA
TTCCTGAATTAGTTTCCCAAAAATTTCTACCTGCCTGTATCAATCATTTG
GACATTTGCTATACGATCCAGAGTTCCAGCAATGAAAATAGCAGTTCTCT
CACACCAGTTCAAGAAATACTTCTACAGAAAATGCGAAGTCATTTACACG
TTGCCATGATTTCCAGATCGGAAGAGGTGGCATATTTAAAAAGTATTAGT
AAATTCCTTATTCCATTAATTACACCAGATTATTTTTCAAGAACTAAAAA
CAAAATTAGTGATCATTTGCTTCAAGAATGCTTTTCTGGAACTGTGCTGC
TGCCAGCCATGGATTCAGTTGCATCACCGGACTTAATCAACAAATTTATT
TATCTATTGCTGACACCATCAACGATTTCAACAGCACTGTGCAATACTCA
ATCGAGTTACGTTCCAATTCTTCATCGATATCAGACTGCGTGGATGGAAA
AACTGAAACGTTTGGAGGAACATCCGAAAGGAATCGAATGCTTAAGGAAT
GAAAAGCATCTTTATCATTTTCTTCAGTACATCAAATCAGTTGAAGCGGT
TTCGGCAGTCAACATTTACTTGGAAATGGATGCAATTATTTTAAAATTAC
TCTCCCCCGACATGGATGAATCTACAAAAATACATATTTTTCAAGACATT
GAGCGATTTGAGAATCTTATTCATTTATCCGATGGAAAGTCTAACTTAAT
CATATCGTCAGATTTGCGTCGACGCATCAAAGAAGCAATAGCTGACGGAT
ACCAAAATGTGGACCGGTTAAGAAATTGTGAAATTTGGATGGAAAATTAT
CAGTTGATTTGTCAACATAATCAGTCTTTGTATTTGTCGCAATATTTTGA
AAGCGAATTCTTCCTGTCAACAATTTACGGTGAACGCCTATCGGATATTG
ATACAAGTTATGAGTGTGAATGGGAAGATATTAATGTAACAGGTGATAGT
CTAAATGTGGTAAATCCCGAAAATCTAGATAATGAAAATCTTTCTCGACA
TGAATCGTCTCCAGAAAATTTTTCTTTTAAAAAAATGTCTTTAGATCTCT
TTAGTTTTGATTTTATGTCCGATCGTAAATCTCCTATCATTGAGGATCAG
AAGTCGGCTTTTTCCACTCCTGATCGAGTAACAGCGCCAGCATTTCCGTT
TTTTCAATTTTTTCAGAAAGAAAAAGAGTTATCTCAAATTGATAAACAAA
AGGAATTTTCAATGACAAAATTTGGATTATCTATCAAACAAGTTTTTACT
GCCAATAGTGACGATTCTTTGAATTTAATTTCTGGGGATCTTGACATAGA
TAATCCTGACGGTTCAGAATGGTTATCGAACTCTTTCGGAGATTTAGTCG
ATCTTCCAGATTTGTCTTATTTAAGAGTCAAAATTCCGTCTATATCTCAG
CCGTATGTTACCAATAAAAAGAAAGGCGAATTATATTTTTCTGTCTATAC
CTATAAAGTTGACTCGGATAAATTACTTTATAAAGTACATAGAAAATATG
GAGAGTTTTATGTACTCGAACAAAAATTGTTAGAATTCCATGGAACTATC
GAACGAGCTCTCCCTCCTAAAAGACCTTGGGATAACAAAAATTTGGACTT
TTTAGAGAAATGCAAACTAGAATTCGAAACGTATTTAATGTATCTAGTCA
ACCGAACCTTCCTCAGAAACAGTGAACTTTTGCACAGATTTCTAACAAGA
CCTACCGAATTCAGTTTCAATTCCCTCATTGATATCAATCTCGGGAAATT
CGTCAAGTCTATGCCCATGATATTTACAAAAGAAAAAGGCCAATTTTTGG
ATCAGTTTCTGTATAATTTCCACATCTCTTGTGAGGCATCTTCGCAGGCT
AAAAGTAATTCTAACAATGATCCGTATTCATCACTCTCGAATTCTGTTTC
TGATCCTGGATCCAAATCTCTATTTGATGCTCGATTGCACACGAGAATGT
ATTGGAATAACGCTGAACTCAATACGATAAAAAGTGAAAATTTTATGAAA
GATATTTGTTCATTTTCCACTAGATATATTTTCTATTACTTCGATAGTTT
GTGTTTCTTTTTCGAAATTATCACCAACAAACTGGCATACTCTCATTTTC
TATTAAATTTCTTTTATCGGATTCGATCAATTCTTGTAGATGTCTTCCAG
ACCTATGTCAAGGGGGTGATTACGAGGGGCTTTGAAAAATTGTGCCATGA
AAAATTAGCAGTGGAAATTATTCATGTTCTTCGAGATGCTGCTCTGTTGT
CTGGATTAAATAGAACGATTTCCGAAAAGCAAGAGCGTCGTAATGAAGCA
TTGACATCTCTCTATCAGTTATTGCCAGGTTGGTTGTCAATCGTTTTGTC
AGATGATCAAATCAAAACTTTATATTCGAACATTGATCGCATTTTTGATT
TTCTGCAACAACCTAAACTGAATAAACAGCTTTCATATGTTCTTTTCGAT
ATTTTACTTTTAGAATTGTTCCCAGAATTGACAGATAATGTTGTTGCTCA
AAATCAGAATGAAGTACCGACCAAAAATTAATAAAGAAAAAATATTTCAC
GGTGTTTTTATTTTTGATAATTTTAAACCCTTGAC
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protein sequence of SMED30008612-orf-1

>SMED30008612-orf-1 ID=SMED30008612-orf-1|Name=SMED30008612-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=968bp
MIYLAIIYGIFFFLLGYLIKFLQTPKNVKQEEDFYLKFKNFRFFSLNDFK
NSKKKPNLYLVENKSIFINSNINSALEEIFDIIIANYINSWYLGFSNNED
FIVEIKYFFHTLCAEILLRFSKISIPELVSQKFLPACINHLDICYTIQSS
SNENSSSLTPVQEILLQKMRSHLHVAMISRSEEVAYLKSISKFLIPLITP
DYFSRTKNKISDHLLQECFSGTVLLPAMDSVASPDLINKFIYLLLTPSTI
STALCNTQSSYVPILHRYQTAWMEKLKRLEEHPKGIECLRNEKHLYHFLQ
YIKSVEAVSAVNIYLEMDAIILKLLSPDMDESTKIHIFQDIERFENLIHL
SDGKSNLIISSDLRRRIKEAIADGYQNVDRLRNCEIWMENYQLICQHNQS
LYLSQYFESEFFLSTIYGERLSDIDTSYECEWEDINVTGDSLNVVNPENL
DNENLSRHESSPENFSFKKMSLDLFSFDFMSDRKSPIIEDQKSAFSTPDR
VTAPAFPFFQFFQKEKELSQIDKQKEFSMTKFGLSIKQVFTANSDDSLNL
ISGDLDIDNPDGSEWLSNSFGDLVDLPDLSYLRVKIPSISQPYVTNKKKG
ELYFSVYTYKVDSDKLLYKVHRKYGEFYVLEQKLLEFHGTIERALPPKRP
WDNKNLDFLEKCKLEFETYLMYLVNRTFLRNSELLHRFLTRPTEFSFNSL
IDINLGKFVKSMPMIFTKEKGQFLDQFLYNFHISCEASSQAKSNSNNDPY
SSLSNSVSDPGSKSLFDARLHTRMYWNNAELNTIKSENFMKDICSFSTRY
IFYYFDSLCFFFEIITNKLAYSHFLLNFFYRIRSILVDVFQTYVKGVITR
GFEKLCHEKLAVEIIHVLRDAALLSGLNRTISEKQERRNEALTSLYQLLP
GWLSIVLSDDQIKTLYSNIDRIFDFLQQPKLNKQLSYVLFDILLLELFPE
LTDNVVAQNQNEVPTKN*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000020protonephridia
PLANA:0000034epidermis
PLANA:0000099neuron
PLANA:0002032epidermal cell
Vocabulary: INTERPRO
TermDefinition
IPR036871PX_dom_sf
IPR003114Phox_assoc
IPR001683Phox
Vocabulary: molecular function
TermDefinition
GO:0035091phosphatidylinositol binding
Vocabulary: cellular component
TermDefinition
GO:0016020membrane
GO:0016021integral component of membrane
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR001683Phox homologous domainSMARTSM00312PX_2coord: 582..692
e-value: 8.2E-8
score: 42.0
IPR001683Phox homologous domainPFAMPF00787PXcoord: 595..690
e-value: 8.0E-12
score: 45.1
IPR001683Phox homologous domainPROSITEPS50195PXcoord: 585..696
score: 11.558
IPR003114Phox-associated domainSMARTSM00313PXA_3coord: 69..249
e-value: 2.4E-10
score: 50.4
IPR003114Phox-associated domainPFAMPF02194PXAcoord: 70..242
e-value: 1.2E-22
score: 80.7
IPR003114Phox-associated domainPROSITEPS51207PXAcoord: 69..249
score: 20.731
IPR036871PX domain superfamilyGENE3DG3DSA:3.30.1520.10coord: 575..705
e-value: 5.6E-20
score: 73.5
IPR036871PX domain superfamilySUPERFAMILYSSF64268PX domaincoord: 589..692
NoneNo IPR availablePANTHERPTHR22775SORTING NEXINcoord: 8..951
NoneNo IPR availablePANTHERPTHR22775:SF44SORTING NEXIN-14coord: 8..951
NoneNo IPR availableTMHMMTMhelixcoord: 2..19