Transcription factor IIIB

Overview
NameTranscription factor IIIB
Smed IDSMED30008583
Length (bp)1220
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Transcription factor IIIB (SMED30008583) t-SNE clustered cells

Violin plots show distribution of expression levels for Transcription factor IIIB (SMED30008583) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Transcription factor IIIB (SMED30008583) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Transcription factor IIIB (SMED30008583) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30008583

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 2

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
X1 cellSMED30008583SMESG000010000.1 SmedASXL_007094SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015		FACS sorted cell population asexual adult RNA-sequencing evidence
neoblastSMED30008583SMESG000010000.1 dd_Smed_v4_3791_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Transcription factor IIIB vs. Ensembl Human
Match: BRF1 (BRF1 RNA polymerase III transcription initiation factor subunit [Source:HGNC Symbol;Acc:HGNC:11551])

HSP 1 Score: 90.1225 bits (222), Expect = 8.529e-19
Identity = 66/295 (22.37%), Postives = 143/295 (48.47%), Query Frame = 3 
Query:   54 CFKCGSVDYDEDFNSRDLICLNCGTIYEGNETQNKVAVLNY------AMGE-----------NFVGGKQEYSGNISRFRLIRRTKQLIYSWCSKLKLSEDLNESSLDYFKKLLDKRKTIGVRKNMIIGVCIYFAAMSKGEPIILLDISNXXXXXXXXXXXXXXXXXXXXXXQFKAQGEYLPLSNDS--TQYSIDPLIFINRFVDYLQFEQKKKEIIQAAMKIVKMLEIDLKEITCSPXXXXXXXXXXXXKLNHIEKSHDQICIKFGICKQTVNKLINKWKKTATAQLPLEEFMRL 881
            C  CG  D + D    D +C  CG++ E N   ++V  +        A+G+              GG     G  SR + ++  ++ I+   ++L+L++   +++ ++FK  + +  T G +   +I  C+Y    ++G P +LLD+S+ L V+V                 +     +L L+ +      +IDP ++I RF   L+F +K  E+   A+++++ ++ D       P+ +   A+++AA+++   ++  ++     +C+ T+ K + +++ T T+QL ++EFM++
Sbjct:    6 CRGCGGTDIELDAARGDAVCTACGSVLEDNIIVSEVQFVESSGGGSSAVGQFVSLDGAGKTPTLGGGFHVNLGKESRAQTLQNGRRHIHHLGNQLQLNQHCLDTAFNFFKMAVSRHLTRGRKMAHVIAACLYLVCRTEGTPHMLLDLSDLLQVNV-----------------YVLGKTFLLLARELCINAPAIDPCLYIPRFAHLLEFGEKNHEVSMTALRLLQRMKRDWMHTGRRPSGLCGAALLVAARMHDFRRTVKEVISVVKVCESTLRKRLTEFEDTPTSQLTIDEFMKI 283
[Close]
BLAST of Transcription factor IIIB vs. Ensembl Human
Match: BRF1 (BRF1 RNA polymerase III transcription initiation factor subunit [Source:HGNC Symbol;Acc:HGNC:11551])

HSP 1 Score: 86.2705 bits (212), Expect = 1.590e-17
Identity = 67/297 (22.56%), Postives = 145/297 (48.82%), Query Frame = 3 
Query:   54 CFKCGSVDYDEDFNSRDLICLNCGTIYEGNETQNKVAVLNYAMGENFVGGKQEYSGNISRFRLIRRTKQLIYSWCSKLKLSEDLNESSLDYFKKLLDKRKTIGVRKNMIIGVCIYFAAMSKGEPIILLDISNXXXXXXXXXXXXXXXXXXXXXXQFKAQGEYLPLSNDS--TQYSIDPLIFINRFVDYLQFEQKKKEIIQAAMKIVKMLEIDLKEITCSPXXXXXXXXXXXXKLNHIEKSHDQICIKFGICKQTVNKLINKWKKTATAQLPLEEFMRLAGPSPPDISEQVEYQIPPT 938
            C  CG  D + D    D +C  CG++ E N   ++V          FV      S  + +F  +   ++ I+   ++L+L++   +++ ++FK  + +  T G +   +I  C+Y    ++G P +LLD+S+ L V+V                 +     +L L+ +      +IDP ++I RF   L+F +K  E+   A+++++ ++ D       P+ +   A+++AA+++   ++  ++     +C+ T+ K + +++ T T+QL ++EFM++      D+ E+ +   PP+
Sbjct:    6 CRGCGGTDIELDAARGDAVCTACGSVLEDNIIVSEV---------QFVESSGGGSSAVGQFVSLD-GRRHIHHLGNQLQLNQHCLDTAFNFFKMAVSRHLTRGRKMAHVIAACLYLVCRTEGTPHMLLDLSDLLQVNV-----------------YVLGKTFLLLARELCINAPAIDPCLYIPRFAHLLEFGEKNHEVSMTALRLLQRMKRDWMHTGRRPSGLCGAALLVAARMHDFRRTVKEVISVVKVCESTLRKRLTEFEDTPTSQLTIDEFMKI------DLEEECD---PPS 266
[Close]
BLAST of Transcription factor IIIB vs. Ensembl Human
Match: BRF1 (BRF1 RNA polymerase III transcription initiation factor subunit [Source:HGNC Symbol;Acc:HGNC:11551])

HSP 1 Score: 60.077 bits (144), Expect = 3.734e-9
Identity = 42/178 (23.60%), Postives = 92/178 (51.69%), Query Frame = 3 
Query:  354 TIGVRKNMIIGVCIYFAAMSKGEPIILLDISNXXXXXXXXXXXXXXXXXXXXXXQFKAQGEYLPLSNDS--TQYSIDPLIFINRFVDYLQFEQKKKEIIQAAMKIVKMLEIDLKEITCSPXXXXXXXXXXXXKLNHIEKSHDQICIKFGICKQTVNKLINKWKKTATAQLPLEEFMRL 881
            T G +   +I  C+Y    ++G P +LLD+S+ L V+V                 +     +L L+ +      +IDP ++I RF   L+F +K  E+   A+++++ ++ D       P+ +   A+++AA+++   ++  ++     +C+ T+ K + +++ T T+QL ++EFM++
Sbjct:    8 TRGRKMAHVIAACLYLVCRTEGTPHMLLDLSDLLQVNV-----------------YVLGKTFLLLARELCINAPAIDPCLYIPRFAHLLEFGEKNHEVSMTALRLLQRMKRDWMHTGRRPSGLCGAALLVAARMHDFRRTVKEVISVVKVCESTLRKRLTEFEDTPTSQLTIDEFMKI 168
[Close]
BLAST of Transcription factor IIIB vs. Ensembl Human
Match: BRF1 (BRF1 RNA polymerase III transcription initiation factor subunit [Source:HGNC Symbol;Acc:HGNC:11551])

HSP 1 Score: 57.7658 bits (138), Expect = 3.818e-9
Identity = 35/149 (23.49%), Postives = 70/149 (46.98%), Query Frame = 3 
Query:   54 CFKCGSVDYDEDFNSRDLICLNCGTIYEGNETQNKVAVLNY------AMGE-----------NFVGGKQEYSGNISRFRLIRRTKQLIYSWCSKLKLSEDLNESSLDYFKKLLDKRKTIGVRKNMIIGVCIYFAAMSKGEPIILLDISN 449
            C  CG  D + D    D +C  CG++ E N   ++V  +        A+G+              GG     G  SR + ++  ++ I+   ++L+L++   +++ ++FK  + +  T G +   +I  C+Y    ++G P +LLD+S+
Sbjct:    6 CRGCGGTDIELDAARGDAVCTACGSVLEDNIIVSEVQFVESSGGGSSAVGQFVSLDGAGKTPTLGGGFHVNLGKESRAQTLQNGRRHIHHLGNQLQLNQHCLDTAFNFFKMAVSRHLTRGRKMAHVIAACLYLVCRTEGTPHMLLDLSD 154
[Close]
BLAST of Transcription factor IIIB vs. Ensembl Human
Match: BRF1 (BRF1 RNA polymerase III transcription initiation factor subunit [Source:HGNC Symbol;Acc:HGNC:11551])

HSP 1 Score: 60.077 bits (144), Expect = 3.993e-9
Identity = 42/178 (23.60%), Postives = 92/178 (51.69%), Query Frame = 3 
Query:  354 TIGVRKNMIIGVCIYFAAMSKGEPIILLDISNXXXXXXXXXXXXXXXXXXXXXXQFKAQGEYLPLSNDS--TQYSIDPLIFINRFVDYLQFEQKKKEIIQAAMKIVKMLEIDLKEITCSPXXXXXXXXXXXXKLNHIEKSHDQICIKFGICKQTVNKLINKWKKTATAQLPLEEFMRL 881
            T G +   +I  C+Y    ++G P +LLD+S+ L V+V                 +     +L L+ +      +IDP ++I RF   L+F +K  E+   A+++++ ++ D       P+ +   A+++AA+++   ++  ++     +C+ T+ K + +++ T T+QL ++EFM++
Sbjct:    8 TRGRKMAHVIAACLYLVCRTEGTPHMLLDLSDLLQVNV-----------------YVLGKTFLLLARELCINAPAIDPCLYIPRFAHLLEFGEKNHEVSMTALRLLQRMKRDWMHTGRRPSGLCGAALLVAARMHDFRRTVKEVISVVKVCESTLRKRLTEFEDTPTSQLTIDEFMKI 168
[Close]
BLAST of Transcription factor IIIB vs. Ensembl Celegans
Match: brf-1 (BRF (Transcription factor) homolog [Source:UniProtKB/TrEMBL;Acc:A0A131MCT5])

HSP 1 Score: 71.633 bits (174), Expect = 3.789e-13
Identity = 65/286 (22.73%), Postives = 125/286 (43.71%), Query Frame = 3 
Query:   54 CFKCGSVDYDEDFNSRDLICLNCGTIYEG------NETQNKVAVLNYAMGENFVGGKQEYSGNI-------SRFRLIRRTKQLIYSWCSKLKLSEDLNESSLDYFKKLLDKRKTIGVRKNMIIGVCIYFAAMSKGEPIILLDISNXXXXXXXXXXXXXXXXXXXXXXQFKAQGEYLPLSNDSTQYSIDPLIFINRFVDYLQFEQKKKEIIQAAMKIVKMLEIDLKEITCSPXXXXXXXXXXXXKLNHIEKSHDQICIKFGICKQTVNKLINKWKKTATAQLPLEEF 872
            C  CGS + DED    D  C  CGT+ E       N+ Q +     + +   FV  ++  + N        SR     + +++I    S+L+++     ++ +++K  + +  T G  ++ ++ VC+Y     +    +LLD S+               +  +          YL  S      S DP ++I RF   L F  K+KE++  A ++V+ ++ D       PT I   A++IAA+  +  +S + I     I +  + K ++++ +T +  L ++EF
Sbjct:    5 CSNCGSSEIDEDAARGDATCTACGTVLEESIVVTENQFQERAGGSGHTLVGQFVSSERAAANNFNGMGSQESREMTYAKGRKVIDELGSQLRINSHCMNTAFNFYKMCVSRNLTRGRNRSSVVAVCMYITCRLENTAHLLLDFSD---------------VTQINVFDLGRNLNYLSRSLRINLPSTDPCLYIMRFACVLDFGDKQKEVVNLATRLVQRMKRDWMSTGRRPTGICGAALLIAARSLNFNRSINDIVRVVHISEGVIRKRLDEFSQTPSGSLTIDEF 275
[Close]
BLAST of Transcription factor IIIB vs. Ensembl Celegans
Match: brf-1 (BRF (Transcription factor) homolog [Source:UniProtKB/TrEMBL;Acc:A0A131MCT5])

HSP 1 Score: 71.633 bits (174), Expect = 3.870e-13
Identity = 65/286 (22.73%), Postives = 125/286 (43.71%), Query Frame = 3 
Query:   54 CFKCGSVDYDEDFNSRDLICLNCGTIYEG------NETQNKVAVLNYAMGENFVGGKQEYSGNI-------SRFRLIRRTKQLIYSWCSKLKLSEDLNESSLDYFKKLLDKRKTIGVRKNMIIGVCIYFAAMSKGEPIILLDISNXXXXXXXXXXXXXXXXXXXXXXQFKAQGEYLPLSNDSTQYSIDPLIFINRFVDYLQFEQKKKEIIQAAMKIVKMLEIDLKEITCSPXXXXXXXXXXXXKLNHIEKSHDQICIKFGICKQTVNKLINKWKKTATAQLPLEEF 872
            C  CGS + DED    D  C  CGT+ E       N+ Q +     + +   FV  ++  + N        SR     + +++I    S+L+++     ++ +++K  + +  T G  ++ ++ VC+Y     +    +LLD S+               +  +          YL  S      S DP ++I RF   L F  K+KE++  A ++V+ ++ D       PT I   A++IAA+  +  +S + I     I +  + K ++++ +T +  L ++EF
Sbjct:    5 CSNCGSSEIDEDAARGDATCTACGTVLEESIVVTENQFQERAGGSGHTLVGQFVSSERAAANNFNGMGSQESREMTYAKGRKVIDELGSQLRINSHCMNTAFNFYKMCVSRNLTRGRNRSSVVAVCMYITCRLENTAHLLLDFSD---------------VTQINVFDLGRNLNYLSRSLRINLPSTDPCLYIMRFACVLDFGDKQKEVVNLATRLVQRMKRDWMSTGRRPTGICGAALLIAARSLNFNRSINDIVRVVHISEGVIRKRLDEFSQTPSGSLTIDEF 275
[Close]
BLAST of Transcription factor IIIB vs. Ensembl Fly
Match: Brf (gene:FBgn0038499 transcript:FBtr0302317)

HSP 1 Score: 85.8853 bits (211), Expect = 9.423e-18
Identity = 77/294 (26.19%), Postives = 136/294 (46.26%), Query Frame = 3 
Query:   51 KCFKCGSVDYDEDFNSRDLICLNCGTIYEGN---------ETQNKVAVLNYAMGENFVGGKQEY--------SGNISRFRLIRRTKQLIYSWCSKLKLSEDLNESSLDYFKKLLDKRKTIGVRKNMIIGVCIYFAAMSKGEPIILLDISNXXXXXXXXXXXXXXXXXXXXXXQFKAQGEYLPLSNDS--TQYSIDPLIFINRFVDYLQFEQKKKEIIQAAMKIVKMLEIDLKEITCSPXXXXXXXXXXXXKLNHIEKSHDQICIKFGICKQTVNKLINKWKKTATAQLPLEEFM 875
            KC  CGS + +ED    D +C+NCG++ E +         E  +  A +   +     GG   Y        SG  SR   I++ K+ I   C +L+LS+   +++L++FK  L +  T G +   I   C+Y    ++G   +L+DIS+                       ++    YL LS+       S+DP ++I RF + LQ   K  E+   A++IV+ ++ D       PT +   A++IAA+++   ++   +     I + T+ K ++++ +T +  L LEEFM
Sbjct:    6 KCRNCGSNEIEEDNARGDRVCMNCGSVLEDSLIVSEVQFEEVGHGAAAIGQFVSAESSGGATNYGYGKFQVGSGTESREVTIKKAKKDITLLCQQLQLSQHYADTALNFFKMALGRHLTRGRKSTHIYAACVYMTCRTEGTSHLLIDISD-----------------VQQICSYELGRTYLKLSHALCINIPSLDPCLYIMRFANRLQLGAKTHEVSMTALRIVQRMKKDCMHSGRRPTGLCGAALLIAARMHDFSRTMLDVIGVVKIHESTLRKRLSEFAETPSGGLTLEEFM 282
[Close]
BLAST of Transcription factor IIIB vs. Ensembl Fly
Match: Brf (gene:FBgn0038499 transcript:FBtr0083452)

HSP 1 Score: 85.8853 bits (211), Expect = 9.423e-18
Identity = 77/294 (26.19%), Postives = 136/294 (46.26%), Query Frame = 3 
Query:   51 KCFKCGSVDYDEDFNSRDLICLNCGTIYEGN---------ETQNKVAVLNYAMGENFVGGKQEY--------SGNISRFRLIRRTKQLIYSWCSKLKLSEDLNESSLDYFKKLLDKRKTIGVRKNMIIGVCIYFAAMSKGEPIILLDISNXXXXXXXXXXXXXXXXXXXXXXQFKAQGEYLPLSNDS--TQYSIDPLIFINRFVDYLQFEQKKKEIIQAAMKIVKMLEIDLKEITCSPXXXXXXXXXXXXKLNHIEKSHDQICIKFGICKQTVNKLINKWKKTATAQLPLEEFM 875
            KC  CGS + +ED    D +C+NCG++ E +         E  +  A +   +     GG   Y        SG  SR   I++ K+ I   C +L+LS+   +++L++FK  L +  T G +   I   C+Y    ++G   +L+DIS+                       ++    YL LS+       S+DP ++I RF + LQ   K  E+   A++IV+ ++ D       PT +   A++IAA+++   ++   +     I + T+ K ++++ +T +  L LEEFM
Sbjct:    6 KCRNCGSNEIEEDNARGDRVCMNCGSVLEDSLIVSEVQFEEVGHGAAAIGQFVSAESSGGATNYGYGKFQVGSGTESREVTIKKAKKDITLLCQQLQLSQHYADTALNFFKMALGRHLTRGRKSTHIYAACVYMTCRTEGTSHLLIDISD-----------------VQQICSYELGRTYLKLSHALCINIPSLDPCLYIMRFANRLQLGAKTHEVSMTALRIVQRMKKDCMHSGRRPTGLCGAALLIAARMHDFSRTMLDVIGVVKIHESTLRKRLSEFAETPSGGLTLEEFM 282
[Close]
BLAST of Transcription factor IIIB vs. Ensembl Zebrafish
Match: brf1a (BRF1 RNA polymerase III transcription initiation factor subunit a [Source:ZFIN;Acc:ZDB-GENE-030131-6334])

HSP 1 Score: 93.9745 bits (232), Expect = 2.949e-20
Identity = 71/300 (23.67%), Postives = 146/300 (48.67%), Query Frame = 3 
Query:   45 MNKCFKCGSVDYDEDFNSRDLICLNCGTIYEGNETQNKVAVLNY------AMGENFVGGKQEYSGNI--------------SRFRLIRRTKQLIYSWCSKLKLSEDLNESSLDYFKKLLDKRKTIGVRKNMIIGVCIYFAAMSKGEPIILLDISNXXXXXXXXXXXXXXXXXXXXXXQFKAQGEYLPLSNDS--TQYSIDPLIFINRFVDYLQFEQKKKEIIQAAMKIVKMLEIDLKEITCSPXXXXXXXXXXXXKLNHIEKSHDQICIKFGICKQTVNKLINKWKKTATAQLPLEEFMR 878
            M +C  CG  D D D      +C+ CG++ E N   ++V  +        A+G+ FV G  + SGN+              SR   ++  K+ I     +L++++   +++ +++K  L K  T G +   +I  C+Y    ++G P +LLD+S+ L V+V                 +     +L L+ +      +IDP ++I RF   L+F +K  E+   A+++++ ++ D       P+ +   A+++AA+++   ++  ++     +C+ T+ K + +++ T T++L +EEFM+
Sbjct:    1 MGRCKTCGGTDIDVDQARGVAVCMGCGSVLEDNIIVSEVTFVESGGGGSSAVGQ-FVAG--DASGNVPSLGGNFQTSVGRESRAATLQNAKRQINHLGHQLQMNQHCLDTAFNFYKMALSKHLTKGRKSTHVIAACLYLVCRTEGTPHMLLDLSDLLQVNV-----------------YVLGKTFLVLARELCINAPAIDPCLYIPRFAQLLEFGEKSHEVSMTALRLLQRMKRDWMHTGRRPSGLCGAALLVAARMHEFRRTIKEVISVVKVCEATLRKRLYEFEDTPTSELTIEEFMK 280
[Close]
BLAST of Transcription factor IIIB vs. Ensembl Zebrafish
Match: brf1a (BRF1 RNA polymerase III transcription initiation factor subunit a [Source:ZFIN;Acc:ZDB-GENE-030131-6334])

HSP 1 Score: 93.9745 bits (232), Expect = 2.949e-20
Identity = 71/300 (23.67%), Postives = 146/300 (48.67%), Query Frame = 3 
Query:   45 MNKCFKCGSVDYDEDFNSRDLICLNCGTIYEGNETQNKVAVLNY------AMGENFVGGKQEYSGNI--------------SRFRLIRRTKQLIYSWCSKLKLSEDLNESSLDYFKKLLDKRKTIGVRKNMIIGVCIYFAAMSKGEPIILLDISNXXXXXXXXXXXXXXXXXXXXXXQFKAQGEYLPLSNDS--TQYSIDPLIFINRFVDYLQFEQKKKEIIQAAMKIVKMLEIDLKEITCSPXXXXXXXXXXXXKLNHIEKSHDQICIKFGICKQTVNKLINKWKKTATAQLPLEEFMR 878
            M +C  CG  D D D      +C+ CG++ E N   ++V  +        A+G+ FV G  + SGN+              SR   ++  K+ I     +L++++   +++ +++K  L K  T G +   +I  C+Y    ++G P +LLD+S+ L V+V                 +     +L L+ +      +IDP ++I RF   L+F +K  E+   A+++++ ++ D       P+ +   A+++AA+++   ++  ++     +C+ T+ K + +++ T T++L +EEFM+
Sbjct:    1 MGRCKTCGGTDIDVDQARGVAVCMGCGSVLEDNIIVSEVTFVESGGGGSSAVGQ-FVAG--DASGNVPSLGGNFQTSVGRESRAATLQNAKRQINHLGHQLQMNQHCLDTAFNFYKMALSKHLTKGRKSTHVIAACLYLVCRTEGTPHMLLDLSDLLQVNV-----------------YVLGKTFLVLARELCINAPAIDPCLYIPRFAQLLEFGEKSHEVSMTALRLLQRMKRDWMHTGRRPSGLCGAALLVAARMHEFRRTIKEVISVVKVCEATLRKRLYEFEDTPTSELTIEEFMK 280
[Close]
BLAST of Transcription factor IIIB vs. Ensembl Zebrafish
Match: brf1b (BRF1 RNA polymerase III transcription initiation factor subunit b [Source:ZFIN;Acc:ZDB-GENE-030131-6248])

HSP 1 Score: 92.4337 bits (228), Expect = 9.629e-20
Identity = 68/296 (22.97%), Postives = 145/296 (48.99%), Query Frame = 3 
Query:   51 KCFKCGSVDYDEDFNSRDLICLNCGTIYEGNETQNKVAVLNYAMG-ENFVG----------------GKQEYSGNISRFRLIRRTKQLIYSWCSKLKLSEDLNESSLDYFKKLLDKRKTIGVRKNMIIGVCIYFAAMSKGEPIILLDISNXXXXXXXXXXXXXXXXXXXXXXQFKAQGEYLPLSNDS--TQYSIDPLIFINRFVDYLQFEQKKKEIIQAAMKIVKMLEIDLKEITCSPXXXXXXXXXXXXKLNHIEKSHDQICIKFGICKQTVNKLINKWKKTATAQLPLEEFMRL 881
            +C  CG  D D D      +C  CG++ E N   ++V  +  + G  + VG                G     G  SR + ++  K+ I++  S+L+L++   +++ ++FK ++ K  T G +   +I  C+Y    ++G P +LLD+S+ L V+V                 +     +L L+ +      ++DP ++I RF   L+F +K  E+   A+++++ ++ D       P+ +   A+++AA+++   ++  ++     +C+ T+ K + ++++T T+ L ++EFMR+
Sbjct:    4 QCKNCGGSDIDTDPARGSAVCTACGSVLEDNIIVSEVQFVENSGGVSSAVGQFVSADGTSKAPVLGSGFHTSLGKESRAQTLQNGKRQIHNLGSQLQLNQHCLDTAFNFFKMVVSKHLTRGRKMTHVIAACLYLVCRTEGTPHMLLDLSDLLQVNV-----------------YILGKTFLLLARELCINAPAVDPCLYIPRFAHMLEFGEKTHEVSMTALRLLQRMKRDWMHTGRRPSGLCGAALLVAARMHEFRRTVKEVISVVKVCEATLRKRLTEFEETPTSSLTIDEFMRV 282
[Close]
BLAST of Transcription factor IIIB vs. Ensembl Zebrafish
Match: brf1b (BRF1 RNA polymerase III transcription initiation factor subunit b [Source:ZFIN;Acc:ZDB-GENE-030131-6248])

HSP 1 Score: 92.4337 bits (228), Expect = 9.629e-20
Identity = 68/296 (22.97%), Postives = 145/296 (48.99%), Query Frame = 3 
Query:   51 KCFKCGSVDYDEDFNSRDLICLNCGTIYEGNETQNKVAVLNYAMG-ENFVG----------------GKQEYSGNISRFRLIRRTKQLIYSWCSKLKLSEDLNESSLDYFKKLLDKRKTIGVRKNMIIGVCIYFAAMSKGEPIILLDISNXXXXXXXXXXXXXXXXXXXXXXQFKAQGEYLPLSNDS--TQYSIDPLIFINRFVDYLQFEQKKKEIIQAAMKIVKMLEIDLKEITCSPXXXXXXXXXXXXKLNHIEKSHDQICIKFGICKQTVNKLINKWKKTATAQLPLEEFMRL 881
            +C  CG  D D D      +C  CG++ E N   ++V  +  + G  + VG                G     G  SR + ++  K+ I++  S+L+L++   +++ ++FK ++ K  T G +   +I  C+Y    ++G P +LLD+S+ L V+V                 +     +L L+ +      ++DP ++I RF   L+F +K  E+   A+++++ ++ D       P+ +   A+++AA+++   ++  ++     +C+ T+ K + ++++T T+ L ++EFMR+
Sbjct:    4 QCKNCGGSDIDTDPARGSAVCTACGSVLEDNIIVSEVQFVENSGGVSSAVGQFVSADGTSKAPVLGSGFHTSLGKESRAQTLQNGKRQIHNLGSQLQLNQHCLDTAFNFFKMVVSKHLTRGRKMTHVIAACLYLVCRTEGTPHMLLDLSDLLQVNV-----------------YILGKTFLLLARELCINAPAVDPCLYIPRFAHMLEFGEKTHEVSMTALRLLQRMKRDWMHTGRRPSGLCGAALLVAARMHEFRRTVKEVISVVKVCEATLRKRLTEFEETPTSSLTIDEFMRV 282
[Close]
BLAST of Transcription factor IIIB vs. Ensembl Zebrafish
Match: brf1b (BRF1 RNA polymerase III transcription initiation factor subunit b [Source:ZFIN;Acc:ZDB-GENE-030131-6248])

HSP 1 Score: 74.7146 bits (182), Expect = 5.040e-14
Identity = 61/295 (20.68%), Postives = 133/295 (45.08%), Query Frame = 3 
Query:   51 KCFKCGSVDYDEDFNSRDLICLNCGTIYEGNETQNKVAVLNYAMG-ENFVG----------------GKQEYSGNISRFRLIRRTKQLIYSWCSKLKLSEDLNESSLDYFKKLLDKRKTIGVRKNMIIGVCIYFAAMS-KGEPIILLDISNXXXXXXXXXXXXXXXXXXXXXXQFKAQGEYLPLSNDSTQYSIDPLIFINRFVDYLQFEQKKKEIIQAAMKIVKMLEIDLKEITCSPXXXXXXXXXXXXKLNHIEKSHDQICIKFGICKQTVNKLINKWKKTATAQLPLEEFMRL 881
            +C  CG  D D D      +C  CG++ E N   ++V  +  + G  + VG                G     G  SR + ++  K+ I++  S+L+L++   +++ ++FK ++ K  T G +   +I  C+Y   +   G+  +LL                                  L ++  +    +DP ++I RF   L+F +K  E+   A+++++ ++ D       P+ +   A+++AA+++   ++  ++     +C+ T+ K + ++++T T+ L ++EFMR+
Sbjct:    4 QCKNCGGSDIDTDPARGSAVCTACGSVLEDNIIVSEVQFVENSGGVSSAVGQFVSADGTSKAPVLGSGFHTSLGKESRAQTLQNGKRQIHNLGSQLQLNQHCLDTAFNFFKMVVSKHLTRGRKMTHVIAACLYLVNVYILGKTFLLL-------------------------------ARELCINAPA----VDPCLYIPRFAHMLEFGEKTHEVSMTALRLLQRMKRDWMHTGRRPSGLCGAALLVAARMHEFRRTVKEVISVVKVCEATLRKRLTEFEETPTSSLTIDEFMRV 263
[Close]
BLAST of Transcription factor IIIB vs. Ensembl Xenopus
Match: npas3 (neuronal PAS domain protein 3 [Source:Xenbase;Acc:XB-GENE-999791])

HSP 1 Score: 93.5893 bits (231), Expect = 5.320e-20
Identity = 71/295 (24.07%), Postives = 145/295 (49.15%), Query Frame = 3 
Query:   54 CFKCGSVDYDEDFNSRDLICLNCGTIYEGNETQNKVAVLNYAMG-ENFVG--------------GKQEYS--GNISRFRLIRRTKQLIYSWCSKLKLSEDLNESSLDYFKKLLDKRKTIGVRKNMIIGVCIYFAAMSKGEPIILLDISNXXXXXXXXXXXXXXXXXXXXXXQFKAQGEYLPLSNDS--TQYSIDPLIFINRFVDYLQFEQKKKEIIQAAMKIVKMLEIDLKEITCSPXXXXXXXXXXXXKLNHIEKSHDQICIKFGICKQTVNKLINKWKKTATAQLPLEEFMRL 881
            C  CG  D D D    D +C  CG++ E N   ++V  +  A G  + VG              G+  Y+  G  SR + ++  K+ I++   +L+L++   +++ ++FK  + K  T G +   +I  C+Y    ++G P +LLD+S+ L V+V                 +     +L L+ +      +IDP ++I RF   L+F  K  E+   A+++V+ ++ D       P+ +   A+++A++++   ++  ++     +C+ T+ K + +++ T T+QL ++EFM++
Sbjct:    6 CKNCGCTDIDVDAARGDAVCTGCGSVLEDNIIVSEVQFVEGAGGISSAVGQFVSSECSGKTPSLGEGFYTSVGKESRAQTLQNGKRQIHNLGVQLQLNKHCLDTAFNFFKMAVSKHLTRGRKMTHVIAACLYLVCRTEGTPHMLLDLSDLLQVNV-----------------YVLGKTFLLLARELCINAPAIDPCLYIPRFAHLLEFGDKNHEVSMTALRLVQRMKRDWMHTGRRPSGLCGAALLVASRMHDFRRTIKEVIRVVKVCESTLRKRLTEFEDTPTSQLTIDEFMKI 283
[Close]
BLAST of Transcription factor IIIB vs. Ensembl Xenopus
Match: npas3 (neuronal PAS domain protein 3 [Source:Xenbase;Acc:XB-GENE-999791])

HSP 1 Score: 93.2041 bits (230), Expect = 5.933e-20
Identity = 71/295 (24.07%), Postives = 145/295 (49.15%), Query Frame = 3 
Query:   54 CFKCGSVDYDEDFNSRDLICLNCGTIYEGNETQNKVAVLNYAMG-ENFVG--------------GKQEYS--GNISRFRLIRRTKQLIYSWCSKLKLSEDLNESSLDYFKKLLDKRKTIGVRKNMIIGVCIYFAAMSKGEPIILLDISNXXXXXXXXXXXXXXXXXXXXXXQFKAQGEYLPLSNDS--TQYSIDPLIFINRFVDYLQFEQKKKEIIQAAMKIVKMLEIDLKEITCSPXXXXXXXXXXXXKLNHIEKSHDQICIKFGICKQTVNKLINKWKKTATAQLPLEEFMRL 881
            C  CG  D D D    D +C  CG++ E N   ++V  +  A G  + VG              G+  Y+  G  SR + ++  K+ I++   +L+L++   +++ ++FK  + K  T G +   +I  C+Y    ++G P +LLD+S+ L V+V                 +     +L L+ +      +IDP ++I RF   L+F  K  E+   A+++V+ ++ D       P+ +   A+++A++++   ++  ++     +C+ T+ K + +++ T T+QL ++EFM++
Sbjct:    6 CKNCGCTDIDVDAARGDAVCTGCGSVLEDNIIVSEVQFVEGAGGISSAVGQFVSSECSGKTPSLGEGFYTSVGKESRAQTLQNGKRQIHNLGVQLQLNKHCLDTAFNFFKMAVSKHLTRGRKMTHVIAACLYLVCRTEGTPHMLLDLSDLLQVNV-----------------YVLGKTFLLLARELCINAPAIDPCLYIPRFAHLLEFGDKNHEVSMTALRLVQRMKRDWMHTGRRPSGLCGAALLVASRMHDFRRTIKEVIRVVKVCESTLRKRLTEFEDTPTSQLTIDEFMKI 283
[Close]
BLAST of Transcription factor IIIB vs. Ensembl Xenopus
Match: npas3 (neuronal PAS domain protein 3 [Source:Xenbase;Acc:XB-GENE-999791])

HSP 1 Score: 93.5893 bits (231), Expect = 6.135e-20
Identity = 71/295 (24.07%), Postives = 145/295 (49.15%), Query Frame = 3 
Query:   54 CFKCGSVDYDEDFNSRDLICLNCGTIYEGNETQNKVAVLNYAMG-ENFVG--------------GKQEYS--GNISRFRLIRRTKQLIYSWCSKLKLSEDLNESSLDYFKKLLDKRKTIGVRKNMIIGVCIYFAAMSKGEPIILLDISNXXXXXXXXXXXXXXXXXXXXXXQFKAQGEYLPLSNDS--TQYSIDPLIFINRFVDYLQFEQKKKEIIQAAMKIVKMLEIDLKEITCSPXXXXXXXXXXXXKLNHIEKSHDQICIKFGICKQTVNKLINKWKKTATAQLPLEEFMRL 881
            C  CG  D D D    D +C  CG++ E N   ++V  +  A G  + VG              G+  Y+  G  SR + ++  K+ I++   +L+L++   +++ ++FK  + K  T G +   +I  C+Y    ++G P +LLD+S+ L V+V                 +     +L L+ +      +IDP ++I RF   L+F  K  E+   A+++V+ ++ D       P+ +   A+++A++++   ++  ++     +C+ T+ K + +++ T T+QL ++EFM++
Sbjct:    6 CKNCGCTDIDVDAARGDAVCTGCGSVLEDNIIVSEVQFVEGAGGISSAVGQFVSSECSGKTPSLGEGFYTSVGKESRAQTLQNGKRQIHNLGVQLQLNKHCLDTAFNFFKMAVSKHLTRGRKMTHVIAACLYLVCRTEGTPHMLLDLSDLLQVNV-----------------YVLGKTFLLLARELCINAPAIDPCLYIPRFAHLLEFGDKNHEVSMTALRLVQRMKRDWMHTGRRPSGLCGAALLVASRMHDFRRTIKEVIRVVKVCESTLRKRLTEFEDTPTSQLTIDEFMKI 283
[Close]
BLAST of Transcription factor IIIB vs. Ensembl Xenopus
Match: npas3 (neuronal PAS domain protein 3 [Source:Xenbase;Acc:XB-GENE-999791])

HSP 1 Score: 77.0258 bits (188), Expect = 1.185e-14
Identity = 64/294 (21.77%), Postives = 133/294 (45.24%), Query Frame = 3 
Query:   54 CFKCGSVDYDEDFNSRDLICLNCGTIYEGNETQNKVAVLNYAMG-ENFVG--------------GKQEYS--GNISRFRLIRRTKQLIYSWCSKLKLSEDLNESSLDYFKKLLDKRKTIGVRKNMIIGVCIYFAAM-SKGEPIILLDISNXXXXXXXXXXXXXXXXXXXXXXQFKAQGEYLPLSNDSTQYSIDPLIFINRFVDYLQFEQKKKEIIQAAMKIVKMLEIDLKEITCSPXXXXXXXXXXXXKLNHIEKSHDQICIKFGICKQTVNKLINKWKKTATAQLPLEEFMRL 881
            C  CG  D D D    D +C  CG++ E N   ++V  +  A G  + VG              G+  Y+  G  SR + ++  K+ I++   +L+L++   +++ ++FK  + K  T G +   +I  C+Y   +   G+  +LL                                  L ++  +    IDP ++I RF   L+F  K  E+   A+++V+ ++ D       P+ +   A+++A++++   ++  ++     +C+ T+ K + +++ T T+QL ++EFM++
Sbjct:    6 CKNCGCTDIDVDAARGDAVCTGCGSVLEDNIIVSEVQFVEGAGGISSAVGQFVSSECSGKTPSLGEGFYTSVGKESRAQTLQNGKRQIHNLGVQLQLNKHCLDTAFNFFKMAVSKHLTRGRKMTHVIAACLYLVNVYVLGKTFLLL-------------------------------ARELCINAPA----IDPCLYIPRFAHLLEFGDKNHEVSMTALRLVQRMKRDWMHTGRRPSGLCGAALLVASRMHDFRRTIKEVIRVVKVCESTLRKRLTEFEDTPTSQLTIDEFMKI 264
[Close]
BLAST of Transcription factor IIIB vs. Ensembl Xenopus
Match: npas3 (neuronal PAS domain protein 3 [Source:Xenbase;Acc:XB-GENE-999791])

HSP 1 Score: 76.6406 bits (187), Expect = 1.760e-14
Identity = 64/294 (21.77%), Postives = 133/294 (45.24%), Query Frame = 3 
Query:   54 CFKCGSVDYDEDFNSRDLICLNCGTIYEGNETQNKVAVLNYAMG-ENFVG--------------GKQEYS--GNISRFRLIRRTKQLIYSWCSKLKLSEDLNESSLDYFKKLLDKRKTIGVRKNMIIGVCIYFAAM-SKGEPIILLDISNXXXXXXXXXXXXXXXXXXXXXXQFKAQGEYLPLSNDSTQYSIDPLIFINRFVDYLQFEQKKKEIIQAAMKIVKMLEIDLKEITCSPXXXXXXXXXXXXKLNHIEKSHDQICIKFGICKQTVNKLINKWKKTATAQLPLEEFMRL 881
            C  CG  D D D    D +C  CG++ E N   ++V  +  A G  + VG              G+  Y+  G  SR + ++  K+ I++   +L+L++   +++ ++FK  + K  T G +   +I  C+Y   +   G+  +LL                                  L ++  +    IDP ++I RF   L+F  K  E+   A+++V+ ++ D       P+ +   A+++A++++   ++  ++     +C+ T+ K + +++ T T+QL ++EFM++
Sbjct:    6 CKNCGCTDIDVDAARGDAVCTGCGSVLEDNIIVSEVQFVEGAGGISSAVGQFVSSECSGKTPSLGEGFYTSVGKESRAQTLQNGKRQIHNLGVQLQLNKHCLDTAFNFFKMAVSKHLTRGRKMTHVIAACLYLVNVYVLGKTFLLL-------------------------------ARELCINAPA----IDPCLYIPRFAHLLEFGDKNHEVSMTALRLVQRMKRDWMHTGRRPSGLCGAALLVASRMHDFRRTIKEVIRVVKVCESTLRKRLTEFEDTPTSQLTIDEFMKI 264
[Close]
BLAST of Transcription factor IIIB vs. Ensembl Mouse
Match: Brf1 (BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit [Source:MGI Symbol;Acc:MGI:1919558])

HSP 1 Score: 94.3597 bits (233), Expect = 2.674e-20
Identity = 71/295 (24.07%), Postives = 144/295 (48.81%), Query Frame = 3 
Query:   54 CFKCGSVDYDEDFNSRDLICLNCGTIYEGNETQNKVA-VLNYAMGENFVG--------GKQEYSGNI--------SRFRLIRRTKQLIYSWCSKLKLSEDLNESSLDYFKKLLDKRKTIGVRKNMIIGVCIYFAAMSKGEPIILLDISNXXXXXXXXXXXXXXXXXXXXXXQFKAQGEYLPLSNDS--TQYSIDPLIFINRFVDYLQFEQKKKEIIQAAMKIVKMLEIDLKEITCSPXXXXXXXXXXXXKLNHIEKSHDQICIKFGICKQTVNKLINKWKKTATAQLPLEEFMRL 881
            C  CG  D + D    D +C  CG++ E N   ++V  V N   G + VG        GK    G          SR + ++  ++ I+   S+L+L++   +++ ++FK  + K  T G +   +I  C+Y    ++G P +LLD+S+ L V+V                 +     +L L+ +      +IDP ++I RF   L+F +K  E+   A+++++ ++ D       P+ +   A+++AA+++   ++  ++     +C+ T+ K + +++ T T+QL ++EFM++
Sbjct:    6 CRGCGGTDIELDAARGDAVCTGCGSVLEDNIIVSEVQFVENSGGGSSAVGQFVSLDGAGKTPTLGGGFHVNLGKESRAQTLQNGRRHIHHLGSQLQLNQHCLDTAFNFFKMAVSKHLTRGRKMAHVIAACLYLVCRTEGTPHMLLDLSDLLQVNV-----------------YVLGKTFLLLARELCINAPAIDPCLYIPRFAHLLEFGEKNHEVSMTALRLLQRMKRDWMHTGRRPSGLCGAALLVAARMHDFRRTVKEVISVVKVCESTLRKRLTEFEDTPTSQLTIDEFMKI 283
[Close]
BLAST of Transcription factor IIIB vs. UniProt/SwissProt
Match: sp|Q8CFK2|TF3B_MOUSE (Transcription factor IIIB 90 kDa subunit OS=Mus musculus OX=10090 GN=Brf1 PE=1 SV=1)

HSP 1 Score: 94.3597 bits (233), Expect = 1.870e-19
Identity = 71/295 (24.07%), Postives = 144/295 (48.81%), Query Frame = 3 
Query:   54 CFKCGSVDYDEDFNSRDLICLNCGTIYEGNETQNKVA-VLNYAMGENFVG--------GKQEYSGNI--------SRFRLIRRTKQLIYSWCSKLKLSEDLNESSLDYFKKLLDKRKTIGVRKNMIIGVCIYFAAMSKGEPIILLDISNXXXXXXXXXXXXXXXXXXXXXXQFKAQGEYLPLSNDS--TQYSIDPLIFINRFVDYLQFEQKKKEIIQAAMKIVKMLEIDLKEITCSPXXXXXXXXXXXXKLNHIEKSHDQICIKFGICKQTVNKLINKWKKTATAQLPLEEFMRL 881
            C  CG  D + D    D +C  CG++ E N   ++V  V N   G + VG        GK    G          SR + ++  ++ I+   S+L+L++   +++ ++FK  + K  T G +   +I  C+Y    ++G P +LLD+S+ L V+V                 +     +L L+ +      +IDP ++I RF   L+F +K  E+   A+++++ ++ D       P+ +   A+++AA+++   ++  ++     +C+ T+ K + +++ T T+QL ++EFM++
Sbjct:    6 CRGCGGTDIELDAARGDAVCTGCGSVLEDNIIVSEVQFVENSGGGSSAVGQFVSLDGAGKTPTLGGGFHVNLGKESRAQTLQNGRRHIHHLGSQLQLNQHCLDTAFNFFKMAVSKHLTRGRKMAHVIAACLYLVCRTEGTPHMLLDLSDLLQVNV-----------------YVLGKTFLLLARELCINAPAIDPCLYIPRFAHLLEFGEKNHEVSMTALRLLQRMKRDWMHTGRRPSGLCGAALLVAARMHDFRRTVKEVISVVKVCESTLRKRLTEFEDTPTSQLTIDEFMKI 283
[Close]
BLAST of Transcription factor IIIB vs. UniProt/SwissProt
Match: sp|Q92994|TF3B_HUMAN (Transcription factor IIIB 90 kDa subunit OS=Homo sapiens OX=9606 GN=BRF1 PE=1 SV=1)

HSP 1 Score: 90.1225 bits (222), Expect = 4.096e-18
Identity = 66/295 (22.37%), Postives = 143/295 (48.47%), Query Frame = 3 
Query:   54 CFKCGSVDYDEDFNSRDLICLNCGTIYEGNETQNKVAVLNY------AMGE-----------NFVGGKQEYSGNISRFRLIRRTKQLIYSWCSKLKLSEDLNESSLDYFKKLLDKRKTIGVRKNMIIGVCIYFAAMSKGEPIILLDISNXXXXXXXXXXXXXXXXXXXXXXQFKAQGEYLPLSNDS--TQYSIDPLIFINRFVDYLQFEQKKKEIIQAAMKIVKMLEIDLKEITCSPXXXXXXXXXXXXKLNHIEKSHDQICIKFGICKQTVNKLINKWKKTATAQLPLEEFMRL 881
            C  CG  D + D    D +C  CG++ E N   ++V  +        A+G+              GG     G  SR + ++  ++ I+   ++L+L++   +++ ++FK  + +  T G +   +I  C+Y    ++G P +LLD+S+ L V+V                 +     +L L+ +      +IDP ++I RF   L+F +K  E+   A+++++ ++ D       P+ +   A+++AA+++   ++  ++     +C+ T+ K + +++ T T+QL ++EFM++
Sbjct:    6 CRGCGGTDIELDAARGDAVCTACGSVLEDNIIVSEVQFVESSGGGSSAVGQFVSLDGAGKTPTLGGGFHVNLGKESRAQTLQNGRRHIHHLGNQLQLNQHCLDTAFNFFKMAVSRHLTRGRKMAHVIAACLYLVCRTEGTPHMLLDLSDLLQVNV-----------------YVLGKTFLLLARELCINAPAIDPCLYIPRFAHLLEFGEKNHEVSMTALRLLQRMKRDWMHTGRRPSGLCGAALLVAARMHDFRRTVKEVISVVKVCESTLRKRLTEFEDTPTSQLTIDEFMKI 283
[Close]
BLAST of Transcription factor IIIB vs. UniProt/SwissProt
Match: sp|P43072|TF3B_CANAL (Transcription factor IIIB 70 kDa subunit OS=Candida albicans (strain SC5314 / ATCC MYA-2876) OX=237561 GN=TDS4 PE=3 SV=1)

HSP 1 Score: 82.0333 bits (201), Expect = 1.769e-15
Identity = 87/337 (25.82%), Postives = 158/337 (46.88%), Query Frame = 3 
Query:   51 KCFKCGSVDYDED--FNSRDLICLNCGTIYEGN---------ETQNKVAVLNYAM------GENFVGGKQEYSGNISRFRLIRRTKQLIYSWCSKLKLSEDLNESSLDYFKKLLDKRKTIGVRKNMIIGVCIYFAAMSKGEPIILLDISNXXXXXXXXXXXXXXXXXXXXXXQFKAQGEYLPLSNDSTQYSIDPLIFINRFVDYLQFEQKKKEIIQAAMKIVKMLEIDLKEITCSPXXXXXXXXXXXXKLNHIEKSHDQICIKFGICKQTVNKLINKWKKTATAQLPLEEFMR---LAGPSPPDISEQVEYQIPPTQMKREIQCEDI-DLSGSDSEE 998
            KC  CG   +D +    + D+ CL CGT+ E N         E+ +  A++  AM         F GG+Q  +   SR + +   K+ I    + LK+ + + E++ ++F+  L      G R N ++  C+Y A   +    +L+D S++L +SVY L     K+   L +        LPL+        DP +FI  FV+ L F+ K  ++ + A+K+   +  D       P  IA   V++AA++N+  +SH +I     + ++T+ + +N++KKT    L ++ F     L   +PP   +    ++  ++  ++ Q ++  DLS    EE
Sbjct:    9 KCKTCGHTQFDVNRYTAAGDVSCLRCGTVLEENPIVSEVQFGESSSGAAMVQGAMVGADQARATFAGGRQ--NAMESREQTLSNGKRKIKRIAAALKIPDYIAEAAGEWFRLALTLNFVQGRRSNNVLATCLYVACRKERTHHMLIDFSSRLQISVYSLGATFLKMVKALHIT------SLPLA--------DPSLFIQHFVEKLDFKDKATKVAKDAVKLAHRMAADWIHEGRRPAGIAGACVLLAARMNNFRRSHAEIVAVSHVGEETLQRRLNEFKKTKAGTLSVKSFREVENLESSNPPSFEKNRAMELKISKKLQQQQTDNFEDLSKMTEEE 329
[Close]
BLAST of Transcription factor IIIB vs. UniProt/SwissProt
Match: sp|P46070|TF3B_KLULA (Transcription factor IIIB 70 kDa subunit OS=Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) OX=284590 GN=TDS4 PE=3 SV=2)

HSP 1 Score: 74.7146 bits (182), Expect = 3.526e-13
Identity = 76/294 (25.85%), Postives = 139/294 (47.28%), Query Frame = 3 
Query:   51 KCFKCGSVDYDEDFN--SRDLICLNCGTIYEGN---------ETQNKVAVLNYAMGENFVGGKQ------EYSGN---ISRFRLIRRTKQLIYSWCSKLKLSEDLNESSLDYFKKLLDKRKTIGVRKNMIIGVCIYFAAMSKGEPIILLDISNXXXXXXXXXXXXXXXXXXXXXXQFKAQGEYLPLSNDSTQYSIDPLIFINRFVDYLQFEQKKKEIIQAAMKIVKMLEIDLKEITCSPXXXXXXXXXXXXKLNHIEKSHDQICIKFGICKQTVNKLINKWKKTATAQLPLEEF 872
            KC  CGS D+  D +  + +LIC  CG + E N         E  N  AV+  A    FV   Q       +SG    +SR   +   ++ + +    L + E + +++  +++  L      G +   +I  C+Y A   +    +L+D S++L VSVY +     KL        K Q   LPL+        DP +FI  F + L+   KK ++I+ A+K+ + +  D       P  IA   +++A ++N++ ++H +I     + ++T+ + +N++K T +A+L ++EF
Sbjct:   11 KCKNCGSTDFVRDISNTTNELICKVCGLVTEENSIVSEVTFGEASNGAAVIQGA----FVSANQAHPTFMSHSGQNALMSRETTLNNARRKLKAVSYALNIPEYVTDAAFQWYRLALSNNFVQGRKSQNVIAACLYIACRKERTHHMLIDFSSRLQVSVYSIGATFLKLAK------KLQIVKLPLA--------DPSLFIQHFAEKLELGDKKIKVIRDAVKLAQTMSRDWMYEGRRPAGIAGACLLLACRMNNLRRTHSEIVAISHVAEETLQQRLNEFKNTTSAKLSVKEF 286
[Close]
BLAST of Transcription factor IIIB vs. UniProt/SwissProt
Match: sp|P29056|TF3B_YEAST (Transcription factor IIIB 70 kDa subunit OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=BRF1 PE=1 SV=1)

HSP 1 Score: 68.5514 bits (166), Expect = 3.492e-11
Identity = 67/289 (23.18%), Postives = 134/289 (46.37%), Query Frame = 3 
Query:   45 MNKCFKCGSVDYDEDFNS--RDLICLNCGTIYEGNETQNKVAVLNYAMGE-----NFVGGKQEY------SGNISRFRLIRRTKQLIYSWCSKLKLSEDLNESSLDYFKKLLDKRKTIGVRKNMIIGVCIYFAAMSKGEPIILLDISNXXXXXXXXXXXXXXXXXXXXXXQFKAQGEYLPLSNDSTQYSIDPLIFINRFVDYLQFEQKKKEIIQAAMKIVKMLEIDLKEITCSPXXXXXXXXXXXXKLNHIEKSHDQICIKFGICKQTVNKLINKWKKTATAQLPLEEF 872
            M  C  C   +++ D ++   DL+C  CG + E N   ++V     + G      +F+G  Q +      S   SR   +   ++ + +    L + E + +++  ++K  L      G R   +I  C+Y A   +    +L+D S++L VSVY +     K+        K     LPL+        DP +FI  F + L    KK ++++ A+K+ + +  D       P  IA   +++A ++N++ ++H +I     + ++T+ + +N++K T  A+L +++F
Sbjct:    1 MPVCKNCHGTEFERDLSNANNDLVCKACGVVSEDNPIVSEVTFGETSAGAAVVQGSFIGAGQSHAAFGGSSALESREATLNNARRKLRAVSYALHIPEYITDAAFQWYKLALANNFVQGRRSQNVIASCLYVACRKEKTHHMLIDFSSRLQVSVYSIGATFLKMVK------KLHITELPLA--------DPSLFIQHFAEKLDLADKKIKVVKDAVKLAQRMSKDWMFEGRRPAGIAGACILLACRMNNLRRTHTEIVAVSHVAEETLQQRLNEFKNTKAAKLSVQKF 275
[Close]
BLAST of Transcription factor IIIB vs. TrEMBL
Match: A0A2I4AIQ0 (transcription factor IIIB 90 kDa subunit-like OS=Austrofundulus limnaeus OX=52670 GN=LOC106511180 PE=4 SV=1)

HSP 1 Score: 110.153 bits (274), Expect = 1.590e-22
Identity = 81/294 (27.55%), Postives = 146/294 (49.66%), Query Frame = 3 
Query:   54 CFKCGSVDYDEDFNSRDLICLNCGTIYEGNETQNKV-----------AVLNYAMGEN-----FVGGKQEYSGNISRFRLIRRTKQLIYSWCSKLKLSEDLNESSLDYFKKLLDKRKTIGVRKNMIIGVCIYFAAMSKGEPIILLDISNXXXXXXXXXXXXXXXXXXXXXXQFKAQGEYLPLSNDS--TQYSIDPLIFINRFVDYLQFEQKKKEIIQAAMKIVKMLEIDLKEITCSPXXXXXXXXXXXXKLNHIEKSHDQICIKFGICKQTVNKLINKWKKTATAQLPLEEFMRL 881
            C  CG  D D D    D +C+ CG++ E N   ++V           AV  +   E      F  G     G+ SR R ++R K+ I +   +L++S+   +++ +++K  L+K  T G R + II  CIY    ++G P +LLD+S+ L V+V                 +     +L LS +      +IDP ++I RF   L+F +K  ++   A+++V+ ++ D       P+ +   A+++AA+L+   ++  +I     +C  T+ K +N+++ T T+QL +EEFMR+
Sbjct:  106 CRTCGGSDIDVDPARGDAVCMGCGSVLEDNIIVSEVEFVESGGGGSLAVGQFVSSEGQKNPLFGDGHGTSLGSESRARTLQRAKEYINTLGHQLQMSQHCLDTAFNFYKMALNKSLTRGRRMDHIIAACIYLVCRTEGTPHMLLDLSDVLQVNV-----------------YILGKTFLLLSRELCINAPAIDPCLYIPRFAQMLEFGEKNHDVSMTALRLVQRMKRDWMHTGRRPSGLCGAALLVAARLHDFCRTIKEIINVVKVCDATLRKRLNEFENTPTSQLTIEEFMRI 382
[Close]
BLAST of Transcription factor IIIB vs. TrEMBL
Match: A0A2I4CC41 (transcription factor IIIB 90 kDa subunit-like OS=Austrofundulus limnaeus OX=52670 GN=LOC106527267 PE=4 SV=1)

HSP 1 Score: 109.768 bits (273), Expect = 3.870e-22
Identity = 79/294 (26.87%), Postives = 145/294 (49.32%), Query Frame = 3 
Query:   54 CFKCGSVDYDEDFNSRDLICLNCGTIYEGNETQNKVAVLNYAMGEN----------------FVGGKQEYSGNISRFRLIRRTKQLIYSWCSKLKLSEDLNESSLDYFKKLLDKRKTIGVRKNMIIGVCIYFAAMSKGEPIILLDISNXXXXXXXXXXXXXXXXXXXXXXQFKAQGEYLPLSNDS--TQYSIDPLIFINRFVDYLQFEQKKKEIIQAAMKIVKMLEIDLKEITCSPXXXXXXXXXXXXKLNHIEKSHDQICIKFGICKQTVNKLINKWKKTATAQLPLEEFMRL 881
            C  CG  D D D    D +C+ CG++ E N   ++V  +    G +                F  G     G+ SR R ++R K+ I +   +L++S+   +++ +++K  L+K  T G R + II  CIY    ++G P +LLD+S+ L V+V                 +     +L LS +      +IDP ++I RF   L+F +K  ++   A+++V+ ++ D       P+ +   A+++AA+L+   ++  +I     +C  T+ K +N+++ T T+QL +EEFMR+
Sbjct:    6 CRTCGGSDIDVDPARGDAVCMGCGSVLEDNIIVSEVEFVESGGGGSLAVGQFVSSEGQKNPLFGDGHGTSLGSESRARTLQRAKEYINTLGHQLQMSQHCLDTAFNFYKMALNKSLTRGRRMDHIIAACIYLVCRTEGTPHMLLDLSDVLQVNV-----------------YILGKTFLLLSRELCINAPAIDPCLYIPRFAQMLEFGEKNHDVSMTALRLVQRMKRDWMHTGRRPSGLCGAALLVAARLHDFCRTIKEIINVVKVCDATLRKRLNEFENTPTSQLTIEEFMRI 282
[Close]
BLAST of Transcription factor IIIB vs. TrEMBL
Match: A0A3Q1EHP1 (BRF1 RNA polymerase III transcription initiation factor subunit a OS=Acanthochromis polyacanthus OX=80966 PE=4 SV=1)

HSP 1 Score: 107.842 bits (268), Expect = 1.697e-21
Identity = 79/298 (26.51%), Postives = 147/298 (49.33%), Query Frame = 3 
Query:   45 MNKCFKCGSVDYDEDFNSRDLICLNCGTIYEGNETQNKVAVLNYAMGENFV--------GGKQEYS---------GNISRFRLIRRTKQLIYSWCSKLKLSEDLNESSLDYFKKLLDKRKTIGVRKNMIIGVCIYFAAMSKGEPIILLDISNXXXXXXXXXXXXXXXXXXXXXXQFKAQGEYLPLSNDS--TQYSIDPLIFINRFVDYLQFEQKKKEIIQAAMKIVKMLEIDLKEITCSPXXXXXXXXXXXXKLNHIEKSHDQICIKFGICKQTVNKLINKWKKTATAQLPLEEFMRL 881
            M  C  CGS + D D +  + +C++CG++ E N   ++V  +    G +          GG +  S         G  SR + ++R KQ I +   +L++S+   +++ +++K  L K  T G R   +I  CIY    ++G P +LLD+S+ L V+V                 F     +L L+ +      +IDP ++I RF   L+F +K  E+   AM++V+ ++ D       P  +   A+++AA+L+   ++  +I     +C+ T+ K + +++ T T+QL +EEFM++
Sbjct:    1 MKSCKNCGSSEIDVDASRGNAVCMSCGSVLEDNIIVSEVEFVETGGGGSLAVGQFVSAEGGAKLPSFGDSHFTGVGKESRAQTLQRAKQHINTLGHQLQMSQHCLDTAFNFYKMALTKHLTRGRRSAHVIAACIYLVCRTEGTPHMLLDLSDLLQVNV-----------------FVLGKTFLVLARELCINAPAIDPCLYIPRFAQLLEFGEKNHEVSMTAMRLVQRMKRDWMHTGRRPAGLCGAALLVAARLHDFRRTIKEIISIVKVCEATLRKRLVEFEDTPTSQLTIEEFMKV 281
[Close]
BLAST of Transcription factor IIIB vs. TrEMBL
Match: M4AVM8 (TFIIB-type domain-containing protein OS=Xiphophorus maculatus OX=8083 PE=4 SV=2)

HSP 1 Score: 107.457 bits (267), Expect = 1.821e-21
Identity = 82/293 (27.99%), Postives = 153/293 (52.22%), Query Frame = 3 
Query:   54 CFKCGSVDYDEDFNSRDLICLNCGTIYEGNETQNKVAVLNYAMGENF-VG--------------GKQEYSG--NISRFRLIRRTKQLIYSWCSKLKLSEDLNESSLDYFKKLLDKRKTIGVRKNMIIGVCIYFAAMSKGEPIILLDISNXXXXXXXXXXXXXXXXXXXXXXQFKAQGEYLPLSNDSTQYSIDPLIFINRFVDYLQFEQKKKEIIQAAMKIVKMLEIDLKEITCSPXXXXXXXXXXXXKLNHIEKSHDQICIKFGICKQTVNKLINKWKKTATAQLPLEEFMRL 881
            C  CGS D D D    D +C+ CG++ E N   ++V  +    G +  VG              G   +SG  + SR + ++R KQ I +   +L++++   +++ +++K  L+K  T G + + I+  CIY    ++G P +LLD+S+ L V+VY L K            F A  + L ++      +IDP ++I RF   L+F +K +E+   A+++V+ ++ D       P+ +   A+++AA+L+   ++  +I     +C+ T+ K + +++ T T+QL +EEFMR+
Sbjct:    6 CKHCGSSDIDVDQARGDAVCMGCGSVLEDNIIVSEVEFVETGGGGSLAVGQFVSSEGGLKNPTFGDGHFSGMGSESRAQTLQRAKQHINTLGHQLQMNQHCLDTAFNFYKMALNKSLTRGRKSDHIMAACIYLVCRTEGTPHMLLDLSDILQVNVYVLGKT-----------FIALAKELCINAP----AIDPCLYIPRFTQMLEFGEKSREVSMTALRLVQRMKRDWMHTGRRPSGLCGAALLVAARLHDFCRTTKEIVNVVKVCESTLRKRLTEFEDTPTSQLTIEEFMRV 283
[Close]
BLAST of Transcription factor IIIB vs. TrEMBL
Match: A0A3P8W7K0 (BRF1 RNA polymerase III transcription initiation factor subunit a OS=Cynoglossus semilaevis OX=244447 PE=4 SV=1)

HSP 1 Score: 106.301 bits (264), Expect = 4.892e-21
Identity = 79/290 (27.24%), Postives = 149/290 (51.38%), Query Frame = 3 
Query:   54 CFKCGSVDYDEDFNSRDLICLNCGTIYEGNETQNKVAVLNYAMG--------------ENFVGGKQEYSGNISRFRLIRRTKQLIYSWCSKLKLSEDLNESSLDYFKKLLDKRKTIGVRKNMIIGVCIYFAAMSKGEPIILLDISNXXXXXXXXXXXXXXXXXXXXXXQFKAQGEYLPLSNDSTQYSIDPLIFINRFVDYLQFEQKKKEIIQAAMKIVKMLEIDLKEITCSPXXXXXXXXXXXXKLNHIEKSHDQICIKFGICKQTVNKLINKWKKTATAQLPLEEFMRL 881
            C  CGS D D D    D +C+ CG++ E N   ++V  +    G              +N V G     G+ SR + + R KQ I +   +L++++   +++ ++++  L K  T G + + II  C+Y    ++G P +LLD+S+ L V+VY L K            F A  + L ++      +IDP ++I RF   L+F +K  E+   A+++V+ ++ D       P+ +   A+++AA+++   ++  +I     +C+ T+ K +N+++ T T+QL +EEFM++
Sbjct:    6 CKNCGSSDIDVDQARGDAVCMGCGSVLEDNIIVSEVEFVETGGGSSLAVGQFVSSEGNKNPVFGDGHGMGSESRAQTLHRAKQQINTLGHQLQMNKHCLDTAYNFYRMALTKHLTRGRKASHIIAACLYLVCRTEGTPHMLLDLSDILQVNVYVLGKT-----------FLALAKELCINAP----AIDPCLYIPRFAHMLEFGEKNHEVSMTALRLVQRMKRDWMHTGRRPSGLCGAALLVAARMHDFCRTTKEIVSVVKVCESTLRKRLNEFEDTPTSQLTIEEFMKV 280
[Close]
BLAST of Transcription factor IIIB vs. Ensembl Cavefish
Match: brf1a (transcription factor IIIB 90 kDa subunit-like [Source:NCBI gene;Acc:103040939])

HSP 1 Score: 100.908 bits (250), Expect = 1.203e-22
Identity = 77/295 (26.10%), Postives = 149/295 (50.51%), Query Frame = 3 
Query:   45 MNKCFKCGSVDYDEDFNSRDLICLNCGTIYEGNETQNKVA-VLNYAMGENFVGG--KQEYSGNI-------------SRFRLIRRTKQLIYSWCSKLKLSEDLNESSLDYFKKLLDKRKTIGVRKNMIIGVCIYFAAMSKGEPIILLDISNXXXXXXXXXXXXXXXXXXXXXXQFKAQGEYLPLSNDSTQYSIDPLIFINRFVDYLQFEQKKKEIIQAAMKIVKMLEIDLKEITCSPXXXXXXXXXXXXKLNHIEKSHDQICIKFGICKQTVNKLINKWKKTATAQLPLEEFMRL 881
            M KC  CG  + D D    D +C+ CG++ E N   ++V  V N   G + VG     + SGN              SR + ++  K+ I     +L++++    ++ +++K  L KR T G +   +I  C+Y    ++G P +LLD+S+ L V+VY L +            F A  + L ++      +IDP +++ RF   L+F +K  E+   A+++V+ ++ D       P+ +   A+++AA+++   ++   +     +C+ T+ K +++++ T T++L +EEFMR+
Sbjct:    1 MRKCKNCGGTNIDVDQTRGDAVCMGCGSVLEDNIIVSEVTFVENSGGGSSAVGQFVASDASGNAPSLGGNFTGMGKESRAQTLQNAKRNINHLGHQLQMNQHCLNTAFNFYKMALCKRLTRGRKSAHVIAACLYLVCRTEGTPHMLLDLSDLLQVNVYVLGRT-----------FLALAKELCIN----APAIDPCLYVPRFAQMLEFGEKSHEVSMTALRLVQRMKRDWMHTGRRPSGLCGAALLVAARMHEFHRTIKDVIGVVKVCEATLRKRLSEFEDTPTSELTIEEFMRV 280
[Close]
BLAST of Transcription factor IIIB vs. Ensembl Cavefish
Match: brf1b (BRF1 RNA polymerase III transcription initiation factor subunit [Source:NCBI gene;Acc:103030783])

HSP 1 Score: 95.1301 bits (235), Expect = 1.235e-20
Identity = 70/296 (23.65%), Postives = 146/296 (49.32%), Query Frame = 3 
Query:   51 KCFKCGSVDYDEDFNSRDLICLNCGTIYEGNETQNKVA-VLNYAMGENFVG--------------GKQEYS--GNISRFRLIRRTKQLIYSWCSKLKLSEDLNESSLDYFKKLLDKRKTIGVRKNMIIGVCIYFAAMSKGEPIILLDISNXXXXXXXXXXXXXXXXXXXXXXQFKAQGEYLPLSNDS--TQYSIDPLIFINRFVDYLQFEQKKKEIIQAAMKIVKMLEIDLKEITCSPXXXXXXXXXXXXKLNHIEKSHDQICIKFGICKQTVNKLINKWKKTATAQLPLEEFMRL 881
            +C  CG  D D D      +C  CG++ E N   ++V  V N   G + +G              G   ++  G  SR + ++  K+ I+S  S+L+L++   +++ ++FK ++ K  T G +   +I  C+Y    ++G P +LLD+S+ L V+V                 +     +L L+ +      ++DP ++I RF   L+F +K  E+   A+++++ ++ D       P+ +   A+++AA+++   ++  ++     +C+ T+ K + +++ T T+ L ++EFMR+
Sbjct:    5 QCQNCGGADIDIDQARGSAVCTACGSVLEDNIIVSEVQFVENSGGGASAIGQFVSADGPVKAPVLGSSFHTSLGKESRVQTLQNGKRQIHSLGSQLQLNQHCLDTAFNFFKMVVSKHLTRGRKMTHVIAACLYLVCRTEGTPHMLLDLSDLLQVNV-----------------YILGKTFLLLARELCINAPAVDPCLYIPRFAHMLEFGEKTHEVSMTALRLLQRMKRDWMHTGRRPSGLCGAALLVAARMHEFRRTVKEVIRVVKVCEATLRKRLTEFEDTPTSHLTIDEFMRV 283
[Close]
BLAST of Transcription factor IIIB vs. Ensembl Cavefish
Match: brf1b (BRF1 RNA polymerase III transcription initiation factor subunit [Source:NCBI gene;Acc:103030783])

HSP 1 Score: 94.7449 bits (234), Expect = 1.259e-20
Identity = 70/296 (23.65%), Postives = 146/296 (49.32%), Query Frame = 3 
Query:   51 KCFKCGSVDYDEDFNSRDLICLNCGTIYEGNETQNKVA-VLNYAMGENFVG--------------GKQEYS--GNISRFRLIRRTKQLIYSWCSKLKLSEDLNESSLDYFKKLLDKRKTIGVRKNMIIGVCIYFAAMSKGEPIILLDISNXXXXXXXXXXXXXXXXXXXXXXQFKAQGEYLPLSNDS--TQYSIDPLIFINRFVDYLQFEQKKKEIIQAAMKIVKMLEIDLKEITCSPXXXXXXXXXXXXKLNHIEKSHDQICIKFGICKQTVNKLINKWKKTATAQLPLEEFMRL 881
            +C  CG  D D D      +C  CG++ E N   ++V  V N   G + +G              G   ++  G  SR + ++  K+ I+S  S+L+L++   +++ ++FK ++ K  T G +   +I  C+Y    ++G P +LLD+S+ L V+V                 +     +L L+ +      ++DP ++I RF   L+F +K  E+   A+++++ ++ D       P+ +   A+++AA+++   ++  ++     +C+ T+ K + +++ T T+ L ++EFMR+
Sbjct:    5 QCQNCGGADIDIDQARGSAVCTACGSVLEDNIIVSEVQFVENSGGGASAIGQFVSADGPVKAPVLGSSFHTSLGKESRVQTLQNGKRQIHSLGSQLQLNQHCLDTAFNFFKMVVSKHLTRGRKMTHVIAACLYLVCRTEGTPHMLLDLSDLLQVNV-----------------YILGKTFLLLARELCINAPAVDPCLYIPRFAHMLEFGEKTHEVSMTALRLLQRMKRDWMHTGRRPSGLCGAALLVAARMHEFRRTVKEVIRVVKVCEATLRKRLTEFEDTPTSHLTIDEFMRV 283
[Close]
BLAST of Transcription factor IIIB vs. Ensembl Cavefish
Match: brf1b (BRF1 RNA polymerase III transcription initiation factor subunit [Source:NCBI gene;Acc:103030783])

HSP 1 Score: 94.7449 bits (234), Expect = 1.279e-20
Identity = 70/296 (23.65%), Postives = 146/296 (49.32%), Query Frame = 3 
Query:   51 KCFKCGSVDYDEDFNSRDLICLNCGTIYEGNETQNKVA-VLNYAMGENFVG--------------GKQEYS--GNISRFRLIRRTKQLIYSWCSKLKLSEDLNESSLDYFKKLLDKRKTIGVRKNMIIGVCIYFAAMSKGEPIILLDISNXXXXXXXXXXXXXXXXXXXXXXQFKAQGEYLPLSNDS--TQYSIDPLIFINRFVDYLQFEQKKKEIIQAAMKIVKMLEIDLKEITCSPXXXXXXXXXXXXKLNHIEKSHDQICIKFGICKQTVNKLINKWKKTATAQLPLEEFMRL 881
            +C  CG  D D D      +C  CG++ E N   ++V  V N   G + +G              G   ++  G  SR + ++  K+ I+S  S+L+L++   +++ ++FK ++ K  T G +   +I  C+Y    ++G P +LLD+S+ L V+V                 +     +L L+ +      ++DP ++I RF   L+F +K  E+   A+++++ ++ D       P+ +   A+++AA+++   ++  ++     +C+ T+ K + +++ T T+ L ++EFMR+
Sbjct:    5 QCQNCGGADIDIDQARGSAVCTACGSVLEDNIIVSEVQFVENSGGGASAIGQFVSADGPVKAPVLGSSFHTSLGKESRVQTLQNGKRQIHSLGSQLQLNQHCLDTAFNFFKMVVSKHLTRGRKMTHVIAACLYLVCRTEGTPHMLLDLSDLLQVNV-----------------YILGKTFLLLARELCINAPAVDPCLYIPRFAHMLEFGEKTHEVSMTALRLLQRMKRDWMHTGRRPSGLCGAALLVAARMHEFRRTVKEVIRVVKVCEATLRKRLTEFEDTPTSHLTIDEFMRV 283
[Close]
BLAST of Transcription factor IIIB vs. Ensembl Yeast
Match: BRF1 (TFIIIB B-related factor; one of three subunits of RNA polymerase III transcription initiation factor TFIIIB, binds TFIIIC and TBP and recruits RNA pol III to promoters, amino-terminal half is homologous to TFIIB; mutations in human homolog are associated with autosomal recessive cerebellar-facial-dental syndrome [Source:SGD;Acc:S000003478])

HSP 1 Score: 68.5514 bits (166), Expect = 5.029e-13
Identity = 67/289 (23.18%), Postives = 134/289 (46.37%), Query Frame = 3 
Query:   45 MNKCFKCGSVDYDEDFNS--RDLICLNCGTIYEGNETQNKVAVLNYAMGE-----NFVGGKQEY------SGNISRFRLIRRTKQLIYSWCSKLKLSEDLNESSLDYFKKLLDKRKTIGVRKNMIIGVCIYFAAMSKGEPIILLDISNXXXXXXXXXXXXXXXXXXXXXXQFKAQGEYLPLSNDSTQYSIDPLIFINRFVDYLQFEQKKKEIIQAAMKIVKMLEIDLKEITCSPXXXXXXXXXXXXKLNHIEKSHDQICIKFGICKQTVNKLINKWKKTATAQLPLEEF 872
            M  C  C   +++ D ++   DL+C  CG + E N   ++V     + G      +F+G  Q +      S   SR   +   ++ + +    L + E + +++  ++K  L      G R   +I  C+Y A   +    +L+D S++L VSVY +     K+        K     LPL+        DP +FI  F + L    KK ++++ A+K+ + +  D       P  IA   +++A ++N++ ++H +I     + ++T+ + +N++K T  A+L +++F
Sbjct:    1 MPVCKNCHGTEFERDLSNANNDLVCKACGVVSEDNPIVSEVTFGETSAGAAVVQGSFIGAGQSHAAFGGSSALESREATLNNARRKLRAVSYALHIPEYITDAAFQWYKLALANNFVQGRRSQNVIASCLYVACRKEKTHHMLIDFSSRLQVSVYSIGATFLKMVK------KLHITELPLA--------DPSLFIQHFAEKLDLADKKIKVVKDAVKLAQRMSKDWMFEGRRPAGIAGACILLACRMNNLRRTHTEIVAVSHVAEETLQQRLNEFKNTKAAKLSVQKF 275
[Close]
BLAST of Transcription factor IIIB vs. Ensembl Nematostella
Match: EDO28578 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T629])

HSP 1 Score: 85.5001 bits (210), Expect = 4.285e-18
Identity = 74/328 (22.56%), Postives = 156/328 (47.56%), Query Frame = 3 
Query:   54 CFKCGSVDYDEDFNSRDLICLNCGTIYEGNETQNKVAVLNYAMGEN-----FVG--GKQEYSG---------NISRFRLIRRTKQLIYSWCSKLKLSEDLNESSLDYFKKLLDKRKTIGVRKNMIIGVCIYFAAMSKGEPIILLDISNXXXXXXXXXXXXXXXXXXXXXXQFKAQGEYLPLSNDS--TQYSIDPLIFINRFVDYLQFEQKKKEIIQAAMKIVKMLEIDLKEITCSPXXXXXXXXXXXXKLNHIEKSHDQICIKFGICKQTVNKLINKWKKTATAQLPLEEFMRLAGPSPPDISEQVEYQIPP----TQMKREIQCEDI 971
            C  CG  D D D +  D +C+ CG++ E N   ++V     ++G       FV   GK+++           +++ F  + + ++ I     +L++++   +++ +++K  ++KR T G R   ++  C+Y    ++  P +LLD S+ L + V                 F     YL L+ +      +IDP ++I+RF   L+  +K+ ++   A+++V  ++ D       P+ +   A+++A++L+   +S  ++     I   T+ K + ++K T ++QL ++EF ++      D+ E+   Q PP     + K + Q ED+
Sbjct:    5 CSNCGGSDIDLDPSRGDAVCMGCGSVLEDNIIVSEVQFQENSLGGTSAIGQFVSSEGKEQFGTPSRGGGTYVHLNHFWSLFKGRKRINQLGHQLQMNQHCIDTAYNFYKLAVNKRLTRGRRTAHVVAACLYLVCRTERTPHMLLDFSDILQIDV-----------------FTLGRAYLKLAQELYINLPAIDPCLYIHRFAHKLELGEKEHDVAVTALRLVSRMKRDWIHHGRRPSGLCGAALLVASRLHSFNRSVREVVKVVRISDTTIRKRLGEFKDTPSSQLTIDEFHKI------DLEEE---QDPPCFTHARKKAKQQAEDV 306
[Close]
BLAST of Transcription factor IIIB vs. Ensembl Nematostella
Match: EDO38124 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SDS0])

HSP 1 Score: 44.669 bits (104), Expect = 9.872e-6
Identity = 34/148 (22.97%), Postives = 63/148 (42.57%), Query Frame = 3 
Query:   54 CFKCGSVDYDEDFNSRDLICLNCGTIYEGN----ETQ--------------------NKVAVLNYAMGENFVGGKQEYSGNISRFRLIRRTKQLIYSWCSKLKLSEDLNESSLDYFKKLLDKRKTIGVRKNMIIGVCIYFAAMSKGEP 425
            C  CG  D D D +  D +C+ CG++ E N    E Q                    NK  +    +G  F  G  + S  I+     +R  QL +    +L++++   +++ +++K  ++KR T G R   ++  C+Y    ++  P
Sbjct:    5 CSNCGGSDIDLDPSRGDAVCMGCGSVLEDNIIVSEVQFQENSLGGTSAIGQFVSSEGNKAGI---GLGTGFRHGLAQESRAITLENGRKRINQLGH----QLQMNQHCIDTAYNFYKLAVNKRLTRGRRTAHVVAACLYLVCRTERTP 145
[Close]
BLAST of Transcription factor IIIB vs. Ensembl Medaka
Match: ENSORLT00000022392.2 (BRF1, RNA polymerase III transcription initiation factor subunit [Source:NCBI gene;Acc:101163291])

HSP 1 Score: 97.4413 bits (241), Expect = 1.812e-21
Identity = 74/295 (25.08%), Postives = 152/295 (51.53%), Query Frame = 3 
Query:   54 CFKCGSVDYDEDFNSRDLICLNCGTIYEGNETQNKVAVLNYAMGENFV--------GGKQEYS---------GNISRFRLIRRTKQLIYSWCSKLKLSEDLNESSLDYFKKLLDKRKTIGVRKNMIIGVCIYFAAMSKGEPIILLDISNXXXXXXXXXXXXXXXXXXXXXXQFKAQGEYLPLSNDS--TQYSIDPLIFINRFVDYLQFEQKKKEIIQAAMKIVKMLEIDLKEITCSPXXXXXXXXXXXXKLNHIEKSHDQICIKFGICKQTVNKLINKWKKTATAQLPLEEFMRL 881
            C  CGS   D D    + +C++CG++ + N   ++V  +    G +          GG++  S         G+ SR + ++R KQ I +   +L++++   +++ +++K  L+KR T G R + +I  C+Y    ++G P +LLD+S+ L V+VY L K+                 +L L+ +      +IDP ++I RF   L+F +K  ++   AM++V+ ++ D       P+ +   A++++A ++   ++  ++     +C+ T+ K + +++ T T++L +EEFMR+
Sbjct:    6 CKNCGSTAIDVDHARGNAVCMSCGSVLDDNIIVSEVEFVETGGGGSLAVGQFVSSEGGQRLPSFGDSYYPGVGSQSRAQTLQRAKQNINTLGHQLQMNQHCLDTAFNFYKMALNKRLTNGHRSSHVIAACLYLVCRTEGTPHMLLDLSDVLQVNVYVLGKV-----------------FLHLAKELCINAPAIDPCLYIPRFAQMLEFGEKNHDVSMTAMRLVQRMKRDWMHTGRRPSGLCGAALLVSAHMHDFCRTVKEVVNVVKVCESTLRKRLTEFEDTPTSKLTVEEFMRV 283
[Close]
BLAST of Transcription factor IIIB vs. Ensembl Medaka
Match: ENSORLT00000022757.2 (pep primary_assembly:ASM223467v1:24:23136217:23147112:-1 gene:ENSORLG00000018171.2 transcript:ENSORLT00000022757.2 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 57.7658 bits (138), Expect = 2.279e-9
Identity = 38/149 (25.50%), Postives = 69/149 (46.31%), Query Frame = 3 
Query:   54 CFKCGSVDYDEDFNSRDLICLNCGTIYEGNETQNKVAVLNYAMG-ENFVG----------------GKQEYSGNISRFRLIRRTKQLIYSWCSKLKLSEDLNESSLDYFKKLLDKRKTIGVRKNMIIGVCIYFAAMSKGEPIILLDISN 449
            C  CG  D D D      +C +CG++ E N   ++V  +  + G  + VG                G     G  SR + ++  K+ I    S+L+L++   +++ ++FK  + K  T G +   +I  C+Y    ++G P +LLD+S+
Sbjct:    6 CKTCGGGDIDVDQARGSAVCTSCGSVLEDNIIVSEVQFVEGSGGVSSAVGQFVSADGPVKAPLLGSGFHTSVGKESRAQTLQNGKRQIQKLGSQLQLNQHCLDTAFNFFKLAVSKHLTRGRKTEHVIAACLYLVCRTEGTPHMLLDLSD 154
[Close]
BLAST of Transcription factor IIIB vs. Planmine SMEST
Match: SMESG000010000.1 (SMESG000010000.1)

HSP 1 Score: 582.408 bits (1500), Expect = 0.000e+0
Identity = 325/342 (95.03%), Postives = 327/342 (95.61%), Query Frame = 3 
Query:   45 MNKCFKCGSVDYDEDFNSRDLICLNCGTIYEGNETQNKVAVLNYAMGENFVGGKQEYSGNISRFRLIRRTKQLIYSWCSKLKLSEDLNESSLDYFKKLLDKRKTIGVRKNMIIGVCIYFAAMSKGEPIILLDISNXXXXXXXXXXXXXXXXXXXXXXQFKAQGEYLPLSNDSTQYSIDPLIFINRFVDYLQFEQKKKEIIQAAMKIVKMLEIDLKEITCSPXXXXXXXXXXXXKLNHIEKSHDQICIKFGICKQTVNKLINKWKKTATAQLPLEEFMRLAGPSPPDISEQVEYQIPPTQMKREIQCEDIDLSGSDSEELEQNYLTSNYKQLSVVSNEKNNQI 1070
            MNKCFKCGSVDYDEDFNSRDLICLNCGTIYEGNETQNKVAVLNYAMGENFVGGKQEYSGNISRFRLIRRTKQLIYSWCSKLKLSEDLNESSLDYFKKLLDKRKTIGVRKNMIIGVCIYFAAMSKGEPIILLDISNKLNVSVYKLVKLSKKLKTVLGLQFKAQ               DPLIFINRFVDYLQFEQKKKEIIQAAMKIVKMLEIDLKEITCSPTAIAVTAVVIAAKLNHIEKSHDQICIKFGICKQTVNKLINKWKKTATAQ+PLEEFMRLAGP+PPDISEQVEYQIPPTQMKREIQCEDIDLSGSDSEELEQNYLTSNYKQLSVVSNEKNNQI
Sbjct:    1 MNKCFKCGSVDYDEDFNSRDLICLNCGTIYEGNETQNKVAVLNYAMGENFVGGKQEYSGNISRFRLIRRTKQLIYSWCSKLKLSEDLNESSLDYFKKLLDKRKTIGVRKNMIIGVCIYFAAMSKGEPIILLDISNKLNVSVYKLVKLSKKLKTVLGLQFKAQ---------------DPLIFINRFVDYLQFEQKKKEIIQAAMKIVKMLEIDLKEITCSPTAIAVTAVVIAAKLNHIEKSHDQICIKFGICKQTVNKLINKWKKTATAQIPLEEFMRLAGPAPPDISEQVEYQIPPTQMKREIQCEDIDLSGSDSEELEQNYLTSNYKQLSVVSNEKNNQI 327
[Close]
BLAST of Transcription factor IIIB vs. Planmine SMEST
Match: SMESG000049775.1 (SMESG000049775.1)

HSP 1 Score: 74.3294 bits (181), Expect = 4.441e-14
Identity = 70/275 (25.45%), Postives = 132/275 (48.00%), Query Frame = 3 
Query:   51 KCFKCGSVDYDEDFNSRDLICLNCGTIYEGNETQNKVAVLNYAMGENFVGGKQEYSG-NISRFRLIRRTKQLIYSWCSKLKLSEDLNESSLDYFKKLLDKRKTIGVRKNMIIGVCIYFAAMSKGEPIILLDISNXXXXXXXXXXXXXXXXXXXXXXQFKAQGEYLPLSNDSTQYSIDPLIFINRFVDYLQFEQKKKEIIQAAMKIVKMLEIDLKEITCSPXXXXXXXXXXXXKLNHIEKSHDQICIKFGICKQTVNKLINKWKKTATAQLPLEEF 872
            +C  C S +  E+  + +++C +CG   E +  + ++     + G     G    +G   ++   I + K  I   C+KL L   +   +L+ +K    +  T G    ++ G C+Y A+  K + ++LLDIS+K+NV+VY L K    +K   G + +                IDP +FINRF   ++   K   +   A+K+++ ++ D       P  +   A+++AAK++H ++ ++ +    G+ + T  K + +W +T TA L L EF
Sbjct:    2 ECKSCRSKNVVENDTNAEIVCEDCGWFCEIDNYKGEIEFHETSNGSKVPVGCLILTGFPAAKQHTINKAKDKINVLCNKLCLEPYVGSYALEIYKSAFMRGLTKGRPALIVAGACLYLASRLKHQSVMLLDISDKINVNVYVLGKTYSVIKESFGQKLQ---------------DIDPCLFINRFAARMELGDKTAIVSMTALKLLQRMKKDWISTGRRPCGVTAAALLLAAKIHHFDRHYEDVARIAGVSEITCRKRLEEWARTPTANLTLSEF 261
The following BLAST results are available for this feature:
BLAST of Transcription factor IIIB vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
BRF18.529e-1922.37BRF1 RNA polymerase III transcription initiation f... [more]
BRF11.590e-1722.56BRF1 RNA polymerase III transcription initiation f... [more]
BRF13.734e-923.60BRF1 RNA polymerase III transcription initiation f... [more]
BRF13.818e-923.49BRF1 RNA polymerase III transcription initiation f... [more]
BRF13.993e-923.60BRF1 RNA polymerase III transcription initiation f... [more]
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BLAST of Transcription factor IIIB vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 2
Match NameE-valueIdentityDescription
brf-13.789e-1322.73BRF (Transcription factor) homolog [Source:UniPro... [more]
brf-13.870e-1322.73BRF (Transcription factor) homolog [Source:UniPro... [more]
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BLAST of Transcription factor IIIB vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 2
Match NameE-valueIdentityDescription
Brf9.423e-1826.19gene:FBgn0038499 transcript:FBtr0302317[more]
Brf9.423e-1826.19gene:FBgn0038499 transcript:FBtr0083452[more]
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BLAST of Transcription factor IIIB vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
brf1a2.949e-2023.67BRF1 RNA polymerase III transcription initiation f... [more]
brf1a2.949e-2023.67BRF1 RNA polymerase III transcription initiation f... [more]
brf1b9.629e-2022.97BRF1 RNA polymerase III transcription initiation f... [more]
brf1b9.629e-2022.97BRF1 RNA polymerase III transcription initiation f... [more]
brf1b5.040e-1420.68BRF1 RNA polymerase III transcription initiation f... [more]
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BLAST of Transcription factor IIIB vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
npas35.320e-2024.07neuronal PAS domain protein 3 [Source:Xenbase;Acc:... [more]
npas35.933e-2024.07neuronal PAS domain protein 3 [Source:Xenbase;Acc:... [more]
npas36.135e-2024.07neuronal PAS domain protein 3 [Source:Xenbase;Acc:... [more]
npas31.185e-1421.77neuronal PAS domain protein 3 [Source:Xenbase;Acc:... [more]
npas31.760e-1421.77neuronal PAS domain protein 3 [Source:Xenbase;Acc:... [more]
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BLAST of Transcription factor IIIB vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 1
Match NameE-valueIdentityDescription
Brf12.674e-2024.07BRF1, RNA polymerase III transcription initiation ... [more]
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BLAST of Transcription factor IIIB vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q8CFK2|TF3B_MOUSE1.870e-1924.07Transcription factor IIIB 90 kDa subunit OS=Mus mu... [more]
sp|Q92994|TF3B_HUMAN4.096e-1822.37Transcription factor IIIB 90 kDa subunit OS=Homo s... [more]
sp|P43072|TF3B_CANAL1.769e-1525.82Transcription factor IIIB 70 kDa subunit OS=Candid... [more]
sp|P46070|TF3B_KLULA3.526e-1325.85Transcription factor IIIB 70 kDa subunit OS=Kluyve... [more]
sp|P29056|TF3B_YEAST3.492e-1123.18Transcription factor IIIB 70 kDa subunit OS=Saccha... [more]
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BLAST of Transcription factor IIIB vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A2I4AIQ01.590e-2227.55transcription factor IIIB 90 kDa subunit-like OS=A... [more]
A0A2I4CC413.870e-2226.87transcription factor IIIB 90 kDa subunit-like OS=A... [more]
A0A3Q1EHP11.697e-2126.51BRF1 RNA polymerase III transcription initiation f... [more]
M4AVM81.821e-2127.99TFIIB-type domain-containing protein OS=Xiphophoru... [more]
A0A3P8W7K04.892e-2127.24BRF1 RNA polymerase III transcription initiation f... [more]
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BLAST of Transcription factor IIIB vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 4
Match NameE-valueIdentityDescription
brf1a1.203e-2226.10transcription factor IIIB 90 kDa subunit-like [Sou... [more]
brf1b1.235e-2023.65BRF1 RNA polymerase III transcription initiation f... [more]
brf1b1.259e-2023.65BRF1 RNA polymerase III transcription initiation f... [more]
brf1b1.279e-2023.65BRF1 RNA polymerase III transcription initiation f... [more]
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BLAST of Transcription factor IIIB vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Transcription factor IIIB vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 1
Match NameE-valueIdentityDescription
BRF15.029e-1323.18TFIIIB B-related factor; one of three subunits of ... [more]
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BLAST of Transcription factor IIIB vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 2
Match NameE-valueIdentityDescription
EDO285784.285e-1822.56Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO381249.872e-622.97Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Transcription factor IIIB vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 2
Match NameE-valueIdentityDescription
ENSORLT00000022392.21.812e-2125.08BRF1, RNA polymerase III transcription initiation ... [more]
ENSORLT00000022757.22.279e-925.50pep primary_assembly:ASM223467v1:24:23136217:23147... [more]
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BLAST of Transcription factor IIIB vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 2
Match NameE-valueIdentityDescription
SMESG000010000.10.000e+095.03SMESG000010000.1[more]
SMESG000049775.14.441e-1425.45SMESG000049775.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30008583 ID=SMED30008583|Name=Transcription factor IIIB|organism=Schmidtea mediterranea sexual|type=transcript|length=1220bp
ATTTATTTGTTTAAATACAAAAATATTTCAAAATATTTTATTAAATGAAT
AAGTGTTTCAAATGTGGTTCTGTGGATTATGATGAGGATTTCAATTCAAG
AGATTTAATTTGTTTAAATTGTGGCACAATATATGAAGGTAATGAAACAC
AGAATAAAGTTGCAGTTCTTAATTATGCAATGGGAGAAAATTTTGTTGGT
GGAAAACAGGAATATTCTGGCAATATTTCTCGATTTCGTTTAATTCGAAG
AACAAAACAATTGATTTATAGTTGGTGCTCTAAATTGAAGTTATCTGAGG
ATTTGAATGAAAGTTCTCTGGATTATTTTAAAAAATTGTTAGATAAACGG
AAAACTATTGGTGTTAGAAAAAACATGATCATTGGAGTTTGTATATATTT
TGCTGCTATGTCAAAAGGCGAACCGATAATACTTCTTGATATTAGTAATA
AATTAAATGTCAGTGTATACAAATTAGTGAAATTGAGTAAGAAACTGAAA
ACTGTACTCGGTTTACAATTCAAAGCACAAGGTGAATATTTACCGTTGTC
AAATGATTCAACGCAATATTCCATAGATCCTTTGATATTTATTAACCGGT
TTGTGGATTATTTGCAATTTGAACAAAAGAAAAAAGAAATCATTCAAGCA
GCAATGAAAATTGTGAAAATGTTGGAAATAGATTTGAAAGAAATCACATG
CAGTCCGACAGCAATTGCTGTCACTGCTGTCGTTATCGCTGCAAAATTGA
ATCACATCGAAAAATCCCATGATCAGATATGTATAAAATTCGGAATCTGC
AAACAAACAGTAAACAAATTGATCAATAAATGGAAAAAGACCGCGACTGC
ACAACTTCCATTGGAGGAATTCATGAGATTAGCCGGCCCATCTCCACCGG
ACATATCCGAGCAAGTGGAATACCAAATCCCTCCGACTCAAATGAAACGG
GAAATCCAATGTGAAGATATCGATCTATCCGGTTCCGACAGTGAGGAATT
GGAACAGAATTATCTCACTAGCAATTACAAGCAGCTGTCGGTTGTTTCTA
ACGAAAAAAATAACCAAATATGAGCCGGGAATCCAAATCCCAATGAAAAG
TAAAATGGACCAATAGAAATCGAGATCTGTATTATACTGTGTTTTTATGC
AATAAATGTTATTTTTTTGGGTTTTTTAAAATTTTATTTATTCTACAAGG
CGTCTGATATCCGATTAATC
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protein sequence of SMED30008583-orf-1

>SMED30008583-orf-1 ID=SMED30008583-orf-1|Name=SMED30008583-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=343bp
MNKCFKCGSVDYDEDFNSRDLICLNCGTIYEGNETQNKVAVLNYAMGENF
VGGKQEYSGNISRFRLIRRTKQLIYSWCSKLKLSEDLNESSLDYFKKLLD
KRKTIGVRKNMIIGVCIYFAAMSKGEPIILLDISNKLNVSVYKLVKLSKK
LKTVLGLQFKAQGEYLPLSNDSTQYSIDPLIFINRFVDYLQFEQKKKEII
QAAMKIVKMLEIDLKEITCSPTAIAVTAVVIAAKLNHIEKSHDQICIKFG
ICKQTVNKLINKWKKTATAQLPLEEFMRLAGPSPPDISEQVEYQIPPTQM
KREIQCEDIDLSGSDSEELEQNYLTSNYKQLSVVSNEKNNQI*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: molecular function
TermDefinition
GO:0000995transcription factor activity, core RNA polymerase III binding
GO:0017025TBP-class protein binding
GO:0008270zinc ion binding
GO:0046872metal ion binding
Vocabulary: biological process
TermDefinition
GO:0006383transcription from RNA polymerase III promoter
GO:0070897DNA-templated transcriptional preinitiation complex assembly
GO:0006352DNA-templated transcription, initiation
GO:0006355regulation of transcription, DNA-templated
GO:0006384transcription initiation from RNA polymerase III promoter
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000429neoblast
PLANA:0002109X1 cell
Vocabulary: INTERPRO
TermDefinition
IPR000812TFIIB
IPR029529Brf1
IPR036915Cyclin-like_sf
IPR013150TFIIB_cyclin
IPR013763Cyclin-like
IPR013137Znf_TFIIB
Vocabulary: cellular component
TermDefinition
GO:0000126transcription factor TFIIIB complex
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableCOILSCoilCoilcoord: 328..342
NoneNo IPR availableGENE3DG3DSA:1.10.472.10coord: 62..161
e-value: 9.8E-15
score: 56.5
NoneNo IPR availableGENE3DG3DSA:1.10.472.10coord: 178..274
e-value: 3.0E-8
score: 35.8
NoneNo IPR availableSUPERFAMILYSSF57783Zinc beta-ribboncoord: 3..36
IPR000812Transcription factor TFIIBPANTHERPTHR11618TRANSCRIPTION INITIATION FACTOR IIB-RELATEDcoord: 1..279
IPR029529Transcription factor IIIB subunit Brf1PANTHERPTHR11618:SF4TRANSCRIPTION FACTOR IIIB 90 KDA SUBUNITcoord: 1..279
IPR013137Zinc finger, TFIIB-typePROSITEPS51134ZF_TFIIBcoord: 1..31
score: 7.731
IPR036915Cyclin-like superfamilySUPERFAMILYSSF47954Cyclin-likecoord: 71..159
IPR036915Cyclin-like superfamilySUPERFAMILYSSF47954Cyclin-likecoord: 177..277