Cytoplasmic dynein 1 heavy chain 1
Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30008568 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 13
Homology
BLAST of Cytoplasmic dynein 1 heavy chain 1 vs. Ensembl Human
Match: DYNC1H1 (dynein cytoplasmic 1 heavy chain 1 [Source:HGNC Symbol;Acc:HGNC:2961]) HSP 1 Score: 6147 bits (15946), Expect = 0.000e+0 Identity = 2962/4618 (64.14%), Postives = 3666/4618 (79.39%), Query Frame = 3 Query: 261 ECLTKFINDNQVTTLTIQQ-TKRXXXXXXXXXXXXKISNEVNFESN---KSQTSIFIKNNQVIEADKTISSQLQVLSYCDGPPFETMHSLVCYGLLPYFXXXXXXXXXXXXXXXXXMVPSVEKKIAELEIGLLHLQQNIEIPEITLTPHPYVAHIIQEKLLQNKEARVSDFEDKFEDTQFLNQLQAGVNRWIKEIQKVTKLNRDPSTGTALQEISFWLNLEHSLDKIQEKRESLEVALTLAILKQAKRFHATTSFDTDTALSSAKIQVKDYNQLMKDFPINDLLSASQLDKISEALQQIFSHLKKVRATKYPVNRIIKLMEALSRDLTTQLMKVISNMHLMSMPYDEFEKIFTACQQVFSTWEDEYDKMQNLLRDIAKKKREEFTKFAWKMNATHKKLQTRLENIKKFRYQHEQLRQVIVRVLKP-VTKVVPSVEAGVPKDQITDKGDKSSTFLPESADTSSIDEVNAAYEIVKVIDCLDFAKEENDEWDAAIKRYEERIDRVESRIASHLRDLLGQSKNANEMFRYFSRFNALFVRPHIRGAIGEYQTQLIQRVKDDIEALHNKFKVQYASSTACKMSKVRDLPPVSGSIIWVRQILRQLNAYMKRVEDVLGKDWAQHIEGQKLKADGESFKLKLNTSELFEEWSKKVAEKSLSVAGSIFNVESTRTVVTVRDREPQKITVLKLKVNFLPDVITLAKEVRNMRALGFRTPLSIVNKAHSANQLYPFAISLIESVRTYESTCSKIEEHKMQNISLLTAGLRKDVQLCIHEGVQITWESYRLDQYVQKLAELVFSFQEKVDDLVIVIKEIDFNVKALETCSYNKQTFEEILIRIQEAVDNMSLHQFSNLAQWVSNLDSLVEQRLIVRLEAGLLEWIKVLKGXXXXXXXXXXXXXXXVNSMAKHRLGGKPQIKKLIHELRITNQQMHLYPSIEVATQDILYQMSSWQNIILNLSRIVHSRYQVGLETE-SDNQKTYKKLLSSLPNSGESLENAYAAVHNILRDANEYVKTWTNYQSLWDLQGDQLFSLIADDNTVWMNVLEEIKSMRKHFDVAETQKEFGPLVIAFGKVQSKVSMKYDNWHKEVLTKFGQNMGKMMTTLYNEVQRARNELEQQSIDSGGTNESVNFITYTQNIKRKMNTWEKQAEACRAGQNILCRDRFQFPNDWLDSENIQGEWSAFKEIMRRKQETISSQVASLQMKITEEDKIVESKTTEVLGNWEKDKPIAGDLTPEEAVNIIQILEGKFNRLKEERENVQKAKEALELTEIGVKPISEEKVTNALSELHDLKNVWNELKSIWEKIRDMKETPWLSVQPRKLRQDIENLTAQLKELPNSFKQYASFEHVRTLLKMYMKVNASIVELKSEAIKERHWRMLMRKLNVSWSLNELQLGKVWDIDLVKNEEIIREVLAIAQGEKALEEYLRQITEVWKNYVLELTNYQSKSKIIKGWDDLFNKVKEHINNVTSMKASPYFKQFEEEATAWEDRLNKINALFDVWIDVQRRWIYLDGIFAGSADIKVLLPVESQRFQSVSTEFLGLMKKVQKSPLVTDVLNIANVQRQLERLADLLGKIQKSLGEYLERQRSSFPRFYFVGDEDLLEIIGNSXXXXXXXXXXXXMFAGVHSIILSEDEKVILGMMSKEGEELRFISPVSIIEHPRINDWLTAMEKEMRVSLAKYLNVAVKEISGWRTESNIDKDKFMVWLDKYQAQIVVLAAQITWSEAVEASLAS------GVSLESTMTVVHSTLNMLADTVLYEQPPVRRRKLEHLIIEYVHQRDVLRALHNDGVSSNKNFDWMSQMRFYFDPKQTDPLHQLSIHVANAKFHYGFEYLGVCDRLVQTPLTDRCYLTMTQALEARLGGSPFGPAGTGKTESVKSLGNQLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLSAVSQQIQGIQEALRELMVSKKDS----INVELLGKQVHVNPDMAIFITMNPGYAGRSNLPDNLKKLFRSLAMTQPDRQLIAQVMLYSQGFRTAEVLAGKVVPFFKLCDEQLSPQSHYDFGLRALKSVLVSAGNVKRDRIKQEKEKIVARGEEINETAIAEQLPEQEILIQSVMETMVPKLIADDIPLLYSLLTDVFPGVEYRQAEMKRLREELRKVSENKFLVYSDEPNTAGYLWVEKVLQLYQITTIHHGLMMVGPSGSGKTMACRVLLQALENIDGIEGVAHIIDPKSISKDSLYGYMDPNTREWTDGLFTHILRRIIDSVRGESNKRQWIVFDGDVDPEWVENLNSVLDDNKLLTLPNGERLAIPPNVRIMFEVQDLKYATLATVSRCGMVWFSEEVLTTGMILTHFLNELKKVQVMEGEEDFSVNQGDTGADADSKISSSPIIQLQTQVSSILAPFFTEDGLIAKCLDYSTTLEHIMDFTRLRALTSLFSMIKQSIRNMIEYNQSHSDFPLNNEQIENYVAKSLISSVVWSMSGDSKLKVREQLSQYIKNISTVDLPTVGGIKNIIDFEVNIQGTWVAWSNKVPQIEVETHKITATDVVVPTMDTVRHEALLYTWLAEHRPVLLCGPPGSGKTMTLFSALRCLPDMEVVGLNFSSATTPELMLKTFDQYCEYRKTPNGIVLAPQQLNKWLIFFCDEINLPDMDKYGTQRVISFLRQMVEHHGFYRITDMQWVSFERIQFVGACNPPTDPGRKPLSHRFLRHVPVVYVDYPGETSLKQIYSTFNRAMLRMLPSLRGYADTLTNAMVEFFLKTQERFTHDMQPHYIYSPREMTRWVRGIHEALKPLESLSVEGLVRIWAHEALRLFQDRLVEEDERHWTDDNINEVALKHFPNINKEEALKRPILYSNWLSKDYSAVTQEELRDYVKARLKVFYEEELDVPLVLFNQVLDHVLRIDRVFRQPQGHLLLIGVSGAGKTTLSRFVSWINGLSVFQVKVHNKYTAEDFDEDLRNVLRRSGCKGEKITFIMDESNVMDSSFLERMNTLLANGEVPGLFEGDELTTLMTQCKEGAIREGLMIDSQEELYKWFTQQICRNLHVVFTMNPSADGLKDKASTSPALFNRCVLNWFGDWSLEAYFQVGKEFTNRLDLERTDYKVPDTLPCIAEGLLPQNPIYRDVVVNALVFVHQTMHQANVRVQKRGGRTAAITPRHYLDLIAHYMKLSAEKRADLEEQQLHLNNGLKKIEQTVDQVEVMQRSLTKKRQELENMNEAANAKLKQMVQDQQEAEQKKTTGQALKEELAKQEQFVNEKQKTVKQELDQVEPTVNEAKQAVQNIRKKDIQEIKAMKNPPNAVKMAVESICLLLGEKTTDWQSILKVIIKDTFVTSILNFNTDDVSDNTRETMKKKYLSNPDYNFEKVNKASNACGPMVKWVLAQISYADILKRVEPLRNELTELSDAAEQNRKKSQETEDLIAQLEKSIAKYTEEYATLISQAQTIKSDLASVESKVGRSVALLGSLSSERTRWDSGSETFKAQMATINGDCLLSSAFMAYGGYFDQHMRTSLFNTWCHHLSEADILFRSDLARVEYLSNPDDRLRWQANSLPADDLCVENAIILRRYNRYPLIIDPSGQATTFLLNEYKEKKITKTSFLDDSFRKTLESALRFGTPLLVQDVESYDPILNPVLNREVRRTGGRTLITLGDQDIDLSPTFTIFLSTRDPSVEFAPDICSRVTFVNFTVTRSSLQNQCLNAVLKIERPDIDQKRSDLLKAQGEFQLKLRHLEKDLLQSLNEAQGNLLENDKIIARLETLKREAADVAKKVEETDVVMQEVESVSTEYVPLAQSCSNIYFTLEAMNQIHFLYQYSLQLMLDIFSSVLINNPELTNVKAASDRLKIITKNLFQVTYNRLARGMLHEDQITFATILARIFLKGSTPIGFLENEFQHFLRSQEATITSSDSNKQDNLGLTLHQDQIDSVKRLKKLKVFAKIEEKVKSTKDIKNWTLTVTPESNVPELWVDDNNYNDEKLSKIAKGMYNLLIIQAIRPDRLLASTQKFIASVLGDTFTESVRGTLDLASIVEVEVTACVPILLCAVQGYDPSGRVEDLASEQGKQLTGIAIGSAEGFSQAEKAINSAAKTGKWVMLKNVHLATSWLVSLEKKIHSLQAHPNFRLFLTMEITPKLPVNLLRAGRVLVFEPPPGIKANLLRTLSSINNQRMSKEPVERSRLYFLLAWLNAIVQERLRYVPLGYSKKYEFGESDFKCALDTIDTWVDGAAMGRTNLPPEKIPWVALQTLLGSCIYGGKIDNAFDQRLLNSFLGYLFTEKCFDHNFALVSDADDGSNIAFPESTKHTDILQWVHKLPDLQTPSWLGLPNSAEKVLLTNLGQSLIGNILKMQQSLEDDEELVVGQSKTK-RTIEVGDGRPAWMRQLYQSTQTWLQILPKSVTPLQRTIENIKDPMYRCFEREVNSGCNLLASVRKDLEDVAEVCKGAKKPTNHHRSMMADLAKGIIPKMWIRYAIPPGLTVIQWIQDFADRIKQLLHISDTAAKSGVIALRSIQVWLGGLFMAEAYITATRQSVAQNNKWALEELFLDVELGEGK---VDSNTCVITGLRLMGSEIVDPRTLKLSTLIYKDIDICRLKWIRVEKSQQLEGSSAKDKVCLPIYLNAARSTVLFTLYF--STTDSSYDFYKRGVAI 14048 E + KF++D QV T+ +++ T +E+ E IS +N + + KS + FIK VI+ADK +SSQL+VL+ + P+ET+HS + + P+FKSYI++ GK M PSVEKKIAELE+GLLHLQQNIEIPEI+L HP + ++ ++ + ++ +V+DF DK ED FLNQLQ+GVNRWI+EIQKVTKL+RDP++GTALQEISFWLNLE +L +IQEKRES EV LTL ILK KRFHAT SFDTDT L A V DYN LMKDFP+NDLLSA++LDKI +AL IF+HL+K+R TKYP+ R ++L+EA+SRDL++QL+KV+ LM + Y+EFEK+ AC +VF TW+DEY+K+Q LLRDI K+KREE K W++N H+KLQ RL+ ++KFR QHEQLR VIVRVL+P VT V + VP+ Q K + L ++AD ++I+EVN AYE VK +D LD +KE + W+AA+KRY+ERIDRVE+RI + LRD LG +KNANEMFR FSRFNALFVRPHIRGAI EYQTQLIQRVKDDIE+LH+KFKVQY S ACKMS VRDLPPVSGSIIW +QI RQL AYMKRVEDVLGK W H+EGQKLK DG+SF++KLNT E+F++W++KV +++L V+G IF +ESTR VR R VLKLKVNFLP++ITL+KEVRN++ LGFR PL+IVNKAH ANQLYPFAISLIESVRTYE TC K+EE ISLL AGL+K+VQ I EG+ + WESY+LD YVQ+LAE VF+FQEKVDDL+I+ ++ID V++LETC Y+ +TF EIL R+Q+AVD+++LH +SNL WV+ LD +E+ L VRL+AGL W +VL G+ + E D DTD H+ GG+P+IK ++HELRITNQ ++L P IE + +M +W+ ++L+L RI RYQVG+ E ++ +K Y+ L+ +P+ +LE +Y+AV I+ + +YVK W YQ LWD+Q + +++ + +D W +L +I+ R FD AET+KEFGP+VI +GKVQSKV++KYD+WHKEVL+KFGQ +G MT ++++ ++R ELEQ S+D+ T+++V FITY Q++KRK+ +EKQ E R GQ +L + RFQFP WL +NI+GEW AF +IMRRK I QVA+LQMKI +ED+ VES+TT++L +WEK KP+ G+L PEEA+ + I EGKF RLK++RE KAKEALELT+ G+ SEE+V AL EL DLK VW+EL +WE+I MKE PW+SVQPRKLRQ+++ L QLK P +QYAS+E V+ LLK YMK+N ++ELKSEA+K+RHW+ LM++L+V+W ++EL LG++WD+DL KNE I+++VL +AQGE ALEE+L+QI EVW Y L+L NYQ+K ++I+GWDDLFNKVKEHIN+V++MK SPY+K FEE+A +WED+LN+I ALFDVWIDVQRRW+YL+GIF GSADIK LLPVE+QRFQS+STEFL LMKKV KSPLV DVLNI VQR LERLADLLGKIQK+LGEYLER+RSSFPRFYFVGDEDLLEIIGNSK++ KLQKHFKKMFAGV SIIL+ED V+LG+ S+EGEE+ F +PVSI EHP+IN+WLT +EKEMRV+LAK L +V E+ + ++ID + ++ W+DKYQAQ+VVL+AQI WSE VE +L+S L S ++ V TLN+LAD+VL EQPP+RRRKLEHLI E VHQRDV R+L + + K+F+W+SQMRFYFDPKQTD L QLSI +ANAKF+YGFEYLGV D+LVQTPLTDRCYLTMTQALEARLGGSPFGPAGTGKTESVK+LG+QLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLSAVSQQ+Q IQEALRE D I ELL KQV V+PDMAIFITMNPGYAGRSNLPDNLKKLFRSLAMT+PDRQLIAQVMLYSQGFRTAEVLA K+VPFFKLCDEQLS QSHYDFGLRALKSVLVSAGNVKR+RI++ K + RGE ++E IAE LPEQEILIQSV ETMVPKL+A+DIPLL+SLL+DVFPGV+Y + EM LREEL+KV + +L Y D G +WVEKVLQLYQIT I+HGLMMVGPSGSGK+MA RVLL+ALE ++G+EGVAHIIDPK+ISKD LYG +DPNTREWTDGLFTH+LR+IIDSVRGE KRQWIVFDGDVDPEWVENLNSVLDDNKLLTLPNGERL++PPNVRIMFEVQDLKYATLATVSRCGMVWFSE+VL+T MI +FL L+ + + EGE++ + G + + + ++SP++Q+Q ++I+ P+FT +GL+ K L+++ LEHIMD TRLR L SLFSM+ Q+ RN+ +YN +H DFP+ EQ+E Y+ + L+ +++WS+SGDS+LK+R +L +YI+ I+TV LPT I IID+EV+I G W W KVPQIEVETHK+ A DVVVPT+DTVRHEALLYTWLAEH+P++LCGPPGSGKTMTLFSALR LPDMEVVGLNFSSATTPEL+LKTFD YCEYR+TPNG+VLAP QL KWL+ FCDEINLPDMDKYGTQRVISF+RQMVEH GFYR +D WV ERIQFVGACNPPTDPGRKPLSHRFLRHVPVVYVDYPG SL QIY TFNRAMLR++PSLR YA+ LT AMVEF+ +QERFT D QPHYIYSPREMTRWVRGI EAL+PLE+L VEGL+RIWAHEALRLFQDRLVE++ER WTD+NI+ VALKHFPNI++E+A+ RPILYSNWLSKDY V QEELRDYVKARLKVFYEEELDVPLVLFN+VLDHVLRIDR+FRQPQGHLLLIGVSGAGKTTLSRFV+W+NGLSV+Q+KVH KYT EDFDEDLR VLRRSGCK EKI FIMDESNV+DS FLERMNTLLANGEVPGLFEGDE TLMTQCKEGA +EGLM+DS EELYKWFT Q+ RNLHVVFTMNPS++GLKD+A+TSPALFNRCVLNWFGDWS EA +QVGKEFT+++DLE+ +Y VPD +P + + L PQ P +R+ +VN+ VFVHQT+HQAN R+ KRGGRT AITPRHYLD I HY L EKR++LEEQQ+HLN GL+KI++TVDQVE ++R L K QELE N AAN KLK+MV+DQQEAE+KK Q ++E+L KQ++ + +KQ +VK++LD+VEP V EA+ AV++I+K+ + E+++M NPP AVK+A+ESICLLLGE TTDW+ I +I+++ F+ +I+NF+ +++SD RE MKK Y+SNP YN+E VN+AS ACGPMVKW +AQ++YAD+LKRVEPLRNEL +L D A+ N++K+ E E +I LE SIA+Y EEYA LIS+AQ IK+DLA+VE+KV RS ALL SLS+ER RW+ SETFK QM+TI GDCLLS+AF+AY GYFDQ MR +LF TW HHL +A+I FR+D+AR EYLSN D+RLRWQA+SLPADDLC ENAI+L+R+NRYPLIIDPSGQAT F++NEYK++KIT+TSFLDD+FRK LESALRFG PLLVQDVESYDP+LNPVLNREVRRTGGR LITLGDQDIDLSP+F IFLSTRDP+VEF PD+CSRVTFVNFTVTRSSLQ+QCLN VLK ERPD+D+KRSDLLK QGEFQL+LR LEK LLQ+LNE +G +L++D II LE LKREAA+V +KVEETD+VMQEVE+VS +Y+PL+ +CS+IYFT+E++ QIHFLYQYSLQ LDI+ +VL NP L V + RL IITK+LFQV +NR+ARGMLH+D ITFA +LARI LKG+ + EFQHFLR E +++ + + GLT+ +Q ++V RL L F + KV++ + W + +PE VP LW ++ + I + ++ LL+IQA RPDRLLA F+++ LG++F + LDL IV EV P+L+C+V GYD SG VEDLA+EQ Q+T IAIGSAEGF+QA+KAIN+A K+G+WVMLKNVHLA WL+ LEKK+HSLQ H FRLFLTMEI PK+PVNLLRAGR+ VFEPPPG+KAN+LRT SSI R+ K P ER+RLYFLLAW +AI+QERLRY PLG+SKKYEFGESD + A DT+DTW+D A GR N+ P+KIPW AL+TL+ IYGG++DN FDQRLLN+FL LFT + FD F L D +I P+ + + +QWV LPD QTPSWLGLPN+AE+VLLT G +I +LKMQ LED+++L +++ K RT DGRPAWMR L+ + WL ++P++++ L+RT+ENIKDP++R FEREV G LL VR+DL DV +VC+G KK TN+ R+++ +L KGI+P+ W Y +P G+TVIQW+ DF++RIKQL +IS AA G L++I V LGGLF+ EAYITATRQ VAQ N W+LEEL L+V + + +D+ + +TGL+L G+ + L LS I + + +L+W++ Q V LP+YLN R+ ++FT+ F +T + FY+RGVA+ Sbjct: 63 EQMRKFLSDPQVHTVLVERSTLKEDVGDEGEEEKEFISYNINIDIHYGVKSNSLAFIKRTPVIDADKPVSSQLRVLTLSEDSPYETLHSFISNAVAPFFKSYIRESGKADRDGDK-MAPSVEKKIAELEMGLLHLQQNIEIPEISLPIHPMITNVAKQCYERGEKPKVTDFGDKVEDPTFLNQLQSGVNRWIREIQKVTKLDRDPASGTALQEISFWLNLERALYRIQEKRESPEVLLTLDILKHGKRFHATVSFDTDTGLKQALETVNDYNPLMKDFPLNDLLSATELDKIRQALVAIFTHLRKIRNTKYPIQRALRLVEAISRDLSSQLLKVLGTRKLMHVAYEEFEKVMVACFEVFQTWDDEYEKLQVLLRDIVKRKREENLKMVWRINPAHRKLQARLDQMRKFRRQHEQLRAVIVRVLRPQVTAVAQQNQGEVPEPQDM----KVAEVLFDAADANAIEEVNLAYENVKEVDGLDVSKEGTEAWEAAMKRYDERIDRVETRITARLRDQLGTAKNANEMFRIFSRFNALFVRPHIRGAIREYQTQLIQRVKDDIESLHDKFKVQYPQSQACKMSHVRDLPPVSGSIIWAKQIDRQLTAYMKRVEDVLGKGWENHVEGQKLKQDGDSFRMKLNTQEIFDDWARKVQQRNLGVSGRIFTIESTR----VRGRTG---NVLKLKVNFLPEIITLSKEVRNLKWLGFRVPLAIVNKAHQANQLYPFAISLIESVRTYERTCEKVEERN--TISLLVAGLKKEVQALIAEGIALVWESYKLDPYVQRLAETVFNFQEKVDDLLIIEEKIDLEVRSLETCMYDHKTFSEILNRVQKAVDDLNLHSYSNLPIWVNKLDMEIERILGVRLQAGLRAWTQVLLGQAEDKAEVDMDTDA---PQVSHKPGGEPKIKNVVHELRITNQVIYLNPPIEECRYKLYQEMFAWKMVVLSLPRIQSQRYQVGVHYELTEEEKFYRNALTRMPDGPVALEESYSAVMGIVSEVEQYVKVWLQYQCLWDMQAENIYNRLGEDLNKWQALLVQIRKARGTFDNAETKKEFGPVVIDYGKVQSKVNLKYDSWHKEVLSKFGQMLGSNMTEFHSQISKSRQELEQHSVDTASTSDAVTFITYVQSLKRKIKQFEKQVELYRNGQRLLEKQRFQFPPSWLYIDNIEGEWGAFNDIMRRKDSAIQQQVANLQMKIVQEDRAVESRTTDLLTDWEKTKPVTGNLRPEEALQALTIYEGKFGRLKDDREKCAKAKEALELTDTGLLSGSEERVQVALEELQDLKGVWSELSKVWEQIDQMKEQPWVSVQPRKLRQNLDALLNQLKSFPARLRQYASYEFVQRLLKGYMKINMLVIELKSEALKDRHWKQLMKRLHVNWVVSELTLGQIWDVDLQKNEAIVKDVLLVAQGEMALEEFLKQIREVWNTYELDLVNYQNKCRLIRGWDDLFNKVKEHINSVSAMKLSPYYKVFEEDALSWEDKLNRIMALFDVWIDVQRRWVYLEGIFTGSADIKHLLPVETQRFQSISTEFLALMKKVSKSPLVMDVLNIQGVQRSLERLADLLGKIQKALGEYLERERSSFPRFYFVGDEDLLEIIGNSKNVAKLQKHFKKMFAGVSSIILNEDNSVVLGISSREGEEVMFKTPVSITEHPKINEWLTLVEKEMRVTLAKLLAESVTEVEIFGKATSIDPNTYITWIDKYQAQLVVLSAQIAWSENVETALSSMGGGGDAAPLHSVLSNVEVTLNVLADSVLMEQPPLRRRKLEHLITELVHQRDVTRSLIKSKIDNAKSFEWLSQMRFYFDPKQTDVLQQLSIQMANAKFNYGFEYLGVQDKLVQTPLTDRCYLTMTQALEARLGGSPFGPAGTGKTESVKALGHQLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLSAVSQQVQCIQEALREHSNPNYDKTSAPITCELLNKQVKVSPDMAIFITMNPGYAGRSNLPDNLKKLFRSLAMTKPDRQLIAQVMLYSQGFRTAEVLANKIVPFFKLCDEQLSSQSHYDFGLRALKSVLVSAGNVKRERIQKIKREKEERGEAVDEGEIAENLPEQEILIQSVCETMVPKLVAEDIPLLFSLLSDVFPGVQYHRGEMTALREELKKVCQEMYLTYGDGEEVGG-MWVEKVLQLYQITQINHGLMMVGPSGSGKSMAWRVLLKALERLEGVEGVAHIIDPKAISKDHLYGTLDPNTREWTDGLFTHVLRKIIDSVRGELQKRQWIVFDGDVDPEWVENLNSVLDDNKLLTLPNGERLSLPPNVRIMFEVQDLKYATLATVSRCGMVWFSEDVLSTDMIFNNFLARLRSIPLDEGEDE--AQRRRKGKEDEGEEAASPMLQIQRDAATIMQPYFTSNGLVTKALEHAFQLEHIMDLTRLRCLGSLFSMLHQACRNVAQYNANHPDFPMQIEQLERYIQRYLVYAILWSLSGDSRLKMRAELGEYIRRITTVPLPTAPNIP-IIDYEVSISGEWSPWQAKVPQIEVETHKVAAPDVVVPTLDTVRHEALLYTWLAEHKPLVLCGPPGSGKTMTLFSALRALPDMEVVGLNFSSATTPELLLKTFDHYCEYRRTPNGVVLAPVQLGKWLVLFCDEINLPDMDKYGTQRVISFIRQMVEHGGFYRTSDQTWVKLERIQFVGACNPPTDPGRKPLSHRFLRHVPVVYVDYPGPASLTQIYGTFNRAMLRLIPSLRTYAEPLTAAMVEFYTMSQERFTQDTQPHYIYSPREMTRWVRGIFEALRPLETLPVEGLIRIWAHEALRLFQDRLVEDEERRWTDENIDTVALKHFPNIDREKAMSRPILYSNWLSKDYIPVDQEELRDYVKARLKVFYEEELDVPLVLFNEVLDHVLRIDRIFRQPQGHLLLIGVSGAGKTTLSRFVAWMNGLSVYQIKVHRKYTGEDFDEDLRTVLRRSGCKNEKIAFIMDESNVLDSGFLERMNTLLANGEVPGLFEGDEYATLMTQCKEGAQKEGLMLDSHEELYKWFTSQVIRNLHVVFTMNPSSEGLKDRAATSPALFNRCVLNWFGDWSTEALYQVGKEFTSKMDLEKPNYIVPDYMPVVYDKL-PQPPSHREAIVNSCVFVHQTLHQANARLAKRGGRTMAITPRHYLDFINHYANLFHEKRSELEEQQMHLNVGLRKIKETVDQVEELRRDLRIKSQELEVKNAAANDKLKKMVKDQQEAEKKKVMSQEIQEQLHKQQEVIADKQMSVKEDLDKVEPAVIEAQNAVKSIKKQHLVEVRSMANPPAAVKLALESICLLLGESTTDWKQIRSIIMRENFIPTIVNFSAEEISDAIREKMKKNYMSNPSYNYEIVNRASLACGPMVKWAIAQLNYADMLKRVEPLRNELQKLEDDAKDNQQKANEVEQMIRDLEASIARYKEEYAVLISEAQAIKADLAAVEAKVNRSTALLKSLSAERERWEKTSETFKNQMSTIAGDCLLSAAFIAYAGYFDQQMRQNLFTTWSHHLQQANIQFRTDIARTEYLSNADERLRWQASSLPADDLCTENAIMLKRFNRYPLIIDPSGQATEFIMNEYKDRKITRTSFLDDAFRKNLESALRFGNPLLVQDVESYDPVLNPVLNREVRRTGGRVLITLGDQDIDLSPSFVIFLSTRDPTVEFPPDLCSRVTFVNFTVTRSSLQSQCLNEVLKAERPDVDEKRSDLLKLQGEFQLRLRQLEKSLLQALNEVKGRILDDDTIITTLENLKREAAEVTRKVEETDIVMQEVETVSQQYLPLSTACSSIYFTMESLKQIHFLYQYSLQFFLDIYHNVLYENPNLKGVTDHTQRLSIITKDLFQVAFNRVARGMLHQDHITFAMLLARIKLKGTVGEPTYDAEFQHFLRGNEIVLSAGSTPRIQ--GLTV--EQAEAVVRLSCLPAFKDLIAKVQADEQFGIWLDSSSPEQTVPYLWSEET-----PATPIGQAIHRLLLIQAFRPDRLLAMAHMFVSTNLGESFMSIMEQPLDLTHIVGTEVKPNTPVLMCSVPGYDASGHVEDLAAEQNTQITSIAIGSAEGFNQADKAINTAVKSGRWVMLKNVHLAPGWLMQLEKKLHSLQPHACFRLFLTMEINPKVPVNLLRAGRIFVFEPPPGVKANMLRTFSSIPVSRICKSPNERARLYFLLAWFHAIIQERLRYAPLGWSKKYEFGESDLRSACDTVDTWLDDTAKGRQNISPDKIPWSALKTLMAQSIYGGRVDNEFDQRLLNTFLERLFTTRSFDSEFKLACKVDGHKDIQMPDGIRREEFVQWVELLPDTQTPSWLGLPNNAERVLLTTQGVDMISKMLKMQM-LEDEDDLAYAETEKKTRTDSTSDGRPAWMRTLHTTASNWLHLIPQTLSHLKRTVENIKDPLFRFFEREVKMGAKLLQDVRQDLADVVQVCEGKKKQTNYLRTLINELVKGILPRSWSHYTVPAGMTVIQWVSDFSERIKQLQNISLAAASGGAKELKNIHVCLGGLFVPEAYITATRQYVAQANSWSLEELCLEVNVTTSQGATLDACSFGVTGLKLQGA-TCNNNKLSLSNAISTALPLTQLRWVK-----QTNTEKKASVVTLPVYLNFTRADLIFTVDFEIATKEDPRSFYERGVAV 4642
BLAST of Cytoplasmic dynein 1 heavy chain 1 vs. Ensembl Human
Match: DYNC1H1 (dynein cytoplasmic 1 heavy chain 1 [Source:HGNC Symbol;Acc:HGNC:2961]) HSP 1 Score: 2617.42 bits (6783), Expect = 0.000e+0 Identity = 1246/2004 (62.18%), Postives = 1542/2004 (76.95%), Query Frame = 3 Query: 8055 NKWLIFFCDEINLPDMDKYGTQRVISFLRQMVEHHGFYRITDMQWVSFERIQFVGACNPPTDPGRKPLSHRFLRHVPVVYVDYPGETSLKQIYSTFNRAMLRMLPSLRGYADTLTNAMVEFFLKTQERFTHDMQPHYIYSPREMTRWVRGIHEALKPLESLSVEGLVRIWAHEALRLFQDRLVEEDERHWTDDNINEVALKHFPNINKEEALKRPILYSNWLSKDYSAVTQEELRDYVKARLKVFYEEELDVPLVLFNQVLDHVLRIDRVFRQPQGHLLLIGVSGAGKTTLSRFVSWINGLSVFQVKVHNKYTAEDFDEDLRNVLRRSGCKGEKITFIMDESNVMDSSFLERMNTLLANGEVPGLFEGDELTTLMTQCKEGAIREGLMIDSQEELYKWFTQQICRNLHVVFTMNPSADGLKDKASTSPALFNRCVLNWFGDWSLEAYFQVGKEFTNRLDLERTDYKVPDTLPCIAEGLLPQNPIYRDVVVNALVFVHQTMHQANVRVQKRGGRTAAITPRHYLDLIAHYMKLSAEKRADLEEQQLHLNNGLKKIEQTVDQVEVMQRSLTKKRQELENMNEAANAKLKQMVQDQQEAEQKKTTGQALKEELAKQEQFVNEKQKTVKQELDQVEPTVNEAKQAVQNIRKKDIQEIKAMKNPPNAVKMAVESICLLLGEKTTDWQSILKVIIKDTFVTSILNFNTDDVSDNTRETMKKKYLSNPDYNFEKVNKASNACGPMVKWVLAQISYADILKRVEPLRNELTELSDAAEQNRKKSQETEDLIAQLEKSIAKYTEEYATLISQAQTIKSDLASVESKVGRSVALLGSLSSERTRWDSGSETFKAQMATINGDCLLSSAFMAYGGYFDQHMRTSLFNTWCHHLSEADILFRSDLARVEYLSNPDDRLRWQANSLPADDLCVENAIILRRYNRYPLIIDPSGQATTFLLNEYKEKKITKTSFLDDSFRKTLESALRFGTPLLVQDVESYDPILNPVLNREVRRTGGRTLITLGDQDIDLSPTFTIFLSTRDPSVEFAPDICSRVTFVNFTVTRSSLQNQCLNAVLKIERPDIDQKRSDLLKAQGEFQLKLRHLEKDLLQSLNEAQGNLLENDKIIARLETLKREAADVAKKVEETDVVMQEVESVSTEYVPLAQSCSNIYFTLEAMNQIHFLYQYSLQLMLDIFSSVLINNPELTNVKAASDRLKIITKNLFQVTYNRLARGMLHEDQITFATILARIFLKGSTPIGFLENEFQHFLRSQEATITSSDSNKQDNLGLTLHQDQIDSVKRLKKLKVFAKIEEKVKSTKDIKNWTLTVTPESNVPELWVDDNNYNDEKLSKIAKGMYNLLIIQAIRPDRLLASTQKFIASVLGDTFTESVRGTLDLASIVEVEVTACVPILLCAVQGYDPSGRVEDLASEQGKQLTGIAIGSAEGFSQAEKAINSAAKTGKWVMLKNVHLATSWLVSLEKKIHSLQAHPNFRLFLTMEITPKLPVNLLRAGRVLVFEPPPGIKANLLRTLSSINNQRMSKEPVERSRLYFLLAWLNAIVQERLRYVPLGYSKKYEFGESDFKCALDTIDTWVDGAAMGRTNLPPEKIPWVALQTLLGSCIYGGKIDNAFDQRLLNSFLGYLFTEKCFDHNFALVSDADDGSNIAFPESTKHTDILQWVHKLPDLQTPSWLGLPNSAEKVLLTNLGQSLIGNILKMQQSLEDDEELVVGQSKTK-RTIEVGDGRPAWMRQLYQSTQTWLQILPKSVTPLQRTIENIKDPMYRCFEREVNSGCNLLASVRKDLEDVAEVCKGAKKPTNHHRSMMADLAKGIIPKMWIRYAIPPGLTVIQWIQDFADRIKQLLHISDTAAKSGVIALRSIQVWLGGLFMAEAYITATRQSVAQNNKWALEELFLDVELGEGK---VDSNTCVITGLRLMGSEIVDPRTLKLSTLIYKDIDICRLKWIRVEKSQQLEGSSAKDKVCLPIYLNAARSTVLFTLYF--STTDSSYDFYKRGVAI 14048 KWL+ FCDEINLPDMDKYGTQRVISF+RQMVEH GFYR +D WV ERIQFVGACNPPTDPGRKPLSHRFLRHVPVVYVDYPG SL QIY TFNRAMLR++PSLR YA+ LT AMVEF+ +QERFT D QPHYIYSPREMTRWVRGI EAL+PLE+L VEGL+RIWAHEALRLFQDRLVE++ER WTD+NI+ VALKHFPNI++E+A+ RPILYSNWLSKDY V QEELRDYVKARLKVFYEEELDVPLVLFN+VLDHVLRIDR+FRQPQGHLLLIGVSGAGKTTLSRFV+W+NGLSV+Q+KVH KYT EDFDEDLR VLRRSGCK EKI FIMDESNV+DS FLERMNTLLANGEVPGLFEGDE TLMTQCKEGA +EGLM+DS EELYKWFT Q+ RNLHVVFTMNPS++GLKD+A+TSPALFNRCVLNWFGDWS EA +QVGKEFT+++DLE+ +Y VPD +P + + LPQ P +R+ +VN+ VFVHQT+HQAN R+ KRGGRT AITPRHYLD I HY L EKR++LEEQQ+HLN GL+KI++TVDQVE ++R L K QELE N AAN KLK+MV+DQQEAE+KK Q ++E+L KQ++ + +KQ +VK++LD+VEP V EA+ AV++I+K+ + E+++M NPP AVK+A+ESICLLLGE TTDW+ I +I+++ F+ +I+NF+ +++SD RE MKK Y+SNP YN+E VN+AS ACGPMVKW +AQ++YAD+LKRVEPLRNEL +L D A+ N++K+ E E +I LE SIA+Y EEYA LIS+AQ IK+DLA+VE+KV RS ALL SLS+ER RW+ SETFK QM+TI GDCLLS+AF+AY GYFDQ MR +LF TW HHL +A+I FR+D+AR EYLSN D+RLRWQA+SLPADDLC ENAI+L+R+NRYPLIIDPSGQAT F++NEYK++KIT+TSFLDD+FRK LESALRFG PLLVQ VEF PD+CSRVTFVNFTVTRSSLQ+QCLN VLK ERPD+D+KRSDLLK QGEFQL+LR LEK LLQ+LNE +G +L++D II LE LKREAA+V +KVEETD+VMQEVE+VS +Y+PL+ +CS+IYFT+E++ QIHFLYQYSLQ LDI+ +VL NP L V + RL IITK+LFQV +NR+ARGMLH+D ITFA +LARI LKG+ + EFQHFLR E +++ + + GLT+ +Q ++V RL L F + KV++ + W + +PE VP LW ++ + I + ++ LL+IQA RPDRLLA F+++ LG++F + LDL IV EV P+L+C+V GYD SG VEDLA+EQ Q+T IAIGSAEGF+QA+KAIN+A K+G+WVMLKNVHLA WL+ LEKK+HSLQ H FRLFLTMEI PK+PVNLLRAGR+ VFEPPPG+KAN+LRT SSI R+ K P ER+RLYFLLAW +AI+QERLRY PLG+SKKYEFGESD + A DT+DTW+D A GR N+ P+KIPW AL+TL+ IYGG++DN FDQRLLN+FL LFT + FD F L D +I P+ + + +QWV LPD QTPSWLGLPN+AE+VLLT G +I +LKMQ LED+++L +++ K RT DGRPAWMR L+ + WL ++P++++ L+RT+ENIKDP++R FEREV G LL VR+DL DV +VC+G KK TN+ R+++ +L KGI+P+ W Y +P G+TVIQW+ DF++RIKQL +IS AA G L++I V LGGLF+ EAYITATRQ VAQ N W+LEEL L+V + + +D+ + +TGL+L G+ + L LS I + + +L+W++ Q V LP+YLN R+ ++FT+ F +T + FY+RGVA+ Sbjct: 1 GKWLVLFCDEINLPDMDKYGTQRVISFIRQMVEHGGFYRTSDQTWVKLERIQFVGACNPPTDPGRKPLSHRFLRHVPVVYVDYPGPASLTQIYGTFNRAMLRLIPSLRTYAEPLTAAMVEFYTMSQERFTQDTQPHYIYSPREMTRWVRGIFEALRPLETLPVEGLIRIWAHEALRLFQDRLVEDEERRWTDENIDTVALKHFPNIDREKAMSRPILYSNWLSKDYIPVDQEELRDYVKARLKVFYEEELDVPLVLFNEVLDHVLRIDRIFRQPQGHLLLIGVSGAGKTTLSRFVAWMNGLSVYQIKVHRKYTGEDFDEDLRTVLRRSGCKNEKIAFIMDESNVLDSGFLERMNTLLANGEVPGLFEGDEYATLMTQCKEGAQKEGLMLDSHEELYKWFTSQVIRNLHVVFTMNPSSEGLKDRAATSPALFNRCVLNWFGDWSTEALYQVGKEFTSKMDLEKPNYIVPDYMPVVYDK-LPQPPSHREAIVNSCVFVHQTLHQANARLAKRGGRTMAITPRHYLDFINHYANLFHEKRSELEEQQMHLNVGLRKIKETVDQVEELRRDLRIKSQELEVKNAAANDKLKKMVKDQQEAEKKKVMSQEIQEQLHKQQEVIADKQMSVKEDLDKVEPAVIEAQNAVKSIKKQHLVEVRSMANPPAAVKLALESICLLLGESTTDWKQIRSIIMRENFIPTIVNFSAEEISDAIREKMKKNYMSNPSYNYEIVNRASLACGPMVKWAIAQLNYADMLKRVEPLRNELQKLEDDAKDNQQKANEVEQMIRDLEASIARYKEEYAVLISEAQAIKADLAAVEAKVNRSTALLKSLSAERERWEKTSETFKNQMSTIAGDCLLSAAFIAYAGYFDQQMRQNLFTTWSHHLQQANIQFRTDIARTEYLSNADERLRWQASSLPADDLCTENAIMLKRFNRYPLIIDPSGQATEFIMNEYKDRKITRTSFLDDAFRKNLESALRFGNPLLVQ-------------------------------------------------VEFPPDLCSRVTFVNFTVTRSSLQSQCLNEVLKAERPDVDEKRSDLLKLQGEFQLRLRQLEKSLLQALNEVKGRILDDDTIITTLENLKREAAEVTRKVEETDIVMQEVETVSQQYLPLSTACSSIYFTMESLKQIHFLYQYSLQFFLDIYHNVLYENPNLKGVTDHTQRLSIITKDLFQVAFNRVARGMLHQDHITFAMLLARIKLKGTVGEPTYDAEFQHFLRGNEIVLSAGSTPRIQ--GLTV--EQAEAVVRLSCLPAFKDLIAKVQADEQFGIWLDSSSPEQTVPYLWSEET-----PATPIGQAIHRLLLIQAFRPDRLLAMAHMFVSTNLGESFMSIMEQPLDLTHIVGTEVKPNTPVLMCSVPGYDASGHVEDLAAEQNTQITSIAIGSAEGFNQADKAINTAVKSGRWVMLKNVHLAPGWLMQLEKKLHSLQPHACFRLFLTMEINPKVPVNLLRAGRIFVFEPPPGVKANMLRTFSSIPVSRICKSPNERARLYFLLAWFHAIIQERLRYAPLGWSKKYEFGESDLRSACDTVDTWLDDTAKGRQNISPDKIPWSALKTLMAQSIYGGRVDNEFDQRLLNTFLERLFTTRSFDSEFKLACKVDGHKDIQMPDGIRREEFVQWVELLPDTQTPSWLGLPNNAERVLLTTQGVDMISKMLKMQM-LEDEDDLAYAETEKKTRTDSTSDGRPAWMRTLHTTASNWLHLIPQTLSHLKRTVENIKDPLFRFFEREVKMGAKLLQDVRQDLADVVQVCEGKKKQTNYLRTLINELVKGILPRSWSHYTVPAGMTVIQWVSDFSERIKQLQNISLAAASGGAKELKNIHVCLGGLFVPEAYITATRQYVAQANSWSLEELCLEVNVTTSQGATLDACSFGVTGLKLQGA-TCNNNKLSLSNAISTALPLTQLRWVK-----QTNTEKKASVVTLPVYLNFTRADLIFTVDFEIATKEDPRSFYERGVAV 1938
BLAST of Cytoplasmic dynein 1 heavy chain 1 vs. Ensembl Human
Match: DYNC1H1 (dynein cytoplasmic 1 heavy chain 1 [Source:HGNC Symbol;Acc:HGNC:2961]) HSP 1 Score: 2607.79 bits (6758), Expect = 0.000e+0 Identity = 1218/1685 (72.28%), Postives = 1438/1685 (85.34%), Query Frame = 3 Query: 5958 FDEFNRLEERMLSAVSQQIQGIQEALRELMVSKKDS----INVELLGKQVHVNPDMAIFITMNPGYAGRSNLPDNLKKLFRSLAMTQPDRQLIAQVMLYSQGFRTAEVLAGKVVPFFKLCDEQLSPQSHYDFGLRALKSVLVSAGNVKRDRIKQEKEKIVARGEEINETAIAEQLPEQEILIQSVMETMVPKLIADDIPLLYSLLTDVFPGVEYRQAEMKRLREELRKVSENKFLVYSDEPNTAGYLWVEKVLQLYQITTIHHGLMMVGPSGSGKTMACRVLLQALENIDGIEGVAHIIDPKSISKDSLYGYMDPNTREWTDGLFTHILRRIIDSVRGESNKRQWIVFDGDVDPEWVENLNSVLDDNKLLTLPNGERLAIPPNVRIMFEVQDLKYATLATVSRCGMVWFSEEVLTTGMILTHFLNELKKVQVMEGEEDFSVNQGDTGADADSKISSSPIIQLQTQVSSILAPFFTEDGLIAKCLDYSTTLEHIMDFTRLRALTSLFSMIKQSIRNMIEYNQSHSDFPLNNEQIENYVAKSLISSVVWSMSGDSKLKVREQLSQYIKNISTVDLPTVGGIKNIIDFEVNIQGTWVAWSNKVPQIEVETHKITATDVVVPTMDTVRHEALLYTWLAEHRPVLLCGPPGSGKTMTLFSALRCLPDMEVVGLNFSSATTPELMLKTFDQYCEYRKTPNGIVLAPQQLNKWLIFFCDEINLPDMDKYGTQRVISFLRQMVEHHGFYRITDMQWVSFERIQFVGACNPPTDPGRKPLSHRFLRHVPVVYVDYPGETSLKQIYSTFNRAMLRMLPSLRGYADTLTNAMVEFFLKTQERFTHDMQPHYIYSPREMTRWVRGIHEALKPLESLSVEGLVRIWAHEALRLFQDRLVEEDERHWTDDNINEVALKHFPNINKEEALKRPILYSNWLSKDYSAVTQEELRDYVKARLKVFYEEELDVPLVLFNQVLDHVLRIDRVFRQPQGHLLLIGVSGAGKTTLSRFVSWINGLSVFQVKVHNKYTAEDFDEDLRNVLRRSGCKGEKITFIMDESNVMDSSFLERMNTLLANGEVPGLFEGDELTTLMTQCKEGAIREGLMIDSQEELYKWFTQQICRNLHVVFTMNPSADGLKDKASTSPALFNRCVLNWFGDWSLEAYFQVGKEFTNRLDLERTDYKVPDTLPCIAEGLLPQNPIYRDVVVNALVFVHQTMHQANVRVQKRGGRTAAITPRHYLDLIAHYMKLSAEKRADLEEQQLHLNNGLKKIEQTVDQVEVMQRSLTKKRQELENMNEAANAKLKQMVQDQQEAEQKKTTGQALKEELAKQEQFVNEKQKTVKQELDQVEPTVNEAKQAVQNIRKKDIQEIKAMKNPPNAVKMAVESICLLLGEKTTDWQSILKVIIKDTFVTSILNFNTDDVSDNTRETMKKKYLSNPDYNFEKVNKASNACGPMVKWVLAQISYADILKRVEPLRNELTELSDAAEQNRKKSQETEDLIAQLEKSIAKYTEEYATLISQAQTIKSDLASVESKVGRSVALLGSLSSERTRWDSGSETFKAQMATINGDCLLSSAFMAYGGYFDQHMRTSLFNTWCHHLSEADILFRSDLARVEYLSNPDDRLRWQANSLPADDLCVENAIILRRYNRYPLIIDPSGQATTFLLNEYKEKKITKTSFLDDSFRKTLESALRFGTPLLVQ 11000 FDEFNRLEERMLSAVSQQ+Q IQEALRE D I ELL KQV V+PDMAIFITMNPGYAGRSNLPDNLKKLFRSLAMT+PDRQLIAQVMLYSQGFRTAEVLA K+VPFFKLCDEQLS QSHYDFGLRALKSVLVSAGNVKR+RI++ K + RGE ++E IAE LPEQEILIQSV ETMVPKL+A+DIPLL+SLL+DVFPGV+Y + EM LREEL+KV + +L Y D G +WVEKVLQLYQIT I+HGLMMVGPSGSGK+MA RVLL+ALE ++G+EGVAHIIDPK+ISKD LYG +DPNTREWTDGLFTH+LR+IIDSVRGE KRQWIVFDGDVDPEWVENLNSVLDDNKLLTLPNGERL++PPNVRIMFEVQDLKYATLATVSRCGMVWFSE+VL+T MI +FL L+ + + EGE++ + G + + + ++SP++Q+Q ++I+ P+FT +GL+ K L+++ LEHIMD TRLR L SLFSM+ Q+ RN+ +YN +H DFP+ EQ+E Y+ + L+ +++WS+SGDS+LK+R +L +YI+ I+TV LPT I IID+EV+I G W W KVPQIEVETHK+ A DVVVPT+DTVRHEALLYTWLAEH+P++LCGPPGSGKTMTLFSALR LPDMEVVGLNFSSATTPEL+LKTFD YCEYR+TPNG+VLAP QL KWL+ FCDEINLPDMDKYGTQRVISF+RQMVEH GFYR +D WV ERIQFVGACNPPTDPGRKPLSHRFLRHVPVVYVDYPG SL QIY TFNRAMLR++PSLR YA+ LT AMVEF+ +QERFT D QPHYIYSPREMTRWVRGI EAL+PLE+L VEGL+RIWAHEALRLFQDRLVE++ER WTD+NI+ VALKHFPNI++E+A+ RPILYSNWLSKDY V QEELRDYVKARLKVFYEEELDVPLVLFN+VLDHVLRIDR+FRQPQGHLLLIGVSGAGKTTLSRFV+W+NGLSV+Q+KVH KYT EDFDEDLR VLRRSGCK EKI FIMDESNV+DS FLERMNTLLANGEVPGLFEGDE TLMTQCKEGA +EGLM+DS EELYKWFT Q+ RNLHVVFTMNPS++GLKD+A+TSPALFNRCVLNWFGDWS EA +QVGKEFT+++DLE+ +Y VPD +P + + LPQ P +R+ +VN+ VFVHQT+HQAN R+ KRGGRT AITPRHYLD I HY L EKR++LEEQQ+HLN GL+KI++TVDQVE ++R L K QELE N AAN KLK+MV+DQQEAE+KK Q ++E+L KQ++ + +KQ +VK++LD+VEP V EA+ AV++I+K+ + E+++M NPP AVK+A+ESICLLLGE TTDW+ I +I+++ F+ +I+NF+ +++SD RE MKK Y+SNP YN+E VN+AS ACGPMVKW +AQ++YAD+LKRVEPLRNEL +L D A+ N++K+ E E +I LE SIA+Y EEYA LIS+AQ IK+DLA+VE+KV RS ALL SLS+ER RW+ SETFK QM+TI GDCLLS+AF+AY GYFDQ MR +LF TW HHL +A+I FR+D+AR EYLSN D+RLRWQA+SLPADDLC ENAI+L+R+NRYPLIIDPSGQAT F++NEYK++KIT+TSFLDD+FRK LESALRFG PLLVQ Sbjct: 2 FDEFNRLEERMLSAVSQQVQCIQEALREHSNPNYDKTSAPITCELLNKQVKVSPDMAIFITMNPGYAGRSNLPDNLKKLFRSLAMTKPDRQLIAQVMLYSQGFRTAEVLANKIVPFFKLCDEQLSSQSHYDFGLRALKSVLVSAGNVKRERIQKIKREKEERGEAVDEGEIAENLPEQEILIQSVCETMVPKLVAEDIPLLFSLLSDVFPGVQYHRGEMTALREELKKVCQEMYLTYGDGEEVGG-MWVEKVLQLYQITQINHGLMMVGPSGSGKSMAWRVLLKALERLEGVEGVAHIIDPKAISKDHLYGTLDPNTREWTDGLFTHVLRKIIDSVRGELQKRQWIVFDGDVDPEWVENLNSVLDDNKLLTLPNGERLSLPPNVRIMFEVQDLKYATLATVSRCGMVWFSEDVLSTDMIFNNFLARLRSIPLDEGEDE--AQRRRKGKEDEGEEAASPMLQIQRDAATIMQPYFTSNGLVTKALEHAFQLEHIMDLTRLRCLGSLFSMLHQACRNVAQYNANHPDFPMQIEQLERYIQRYLVYAILWSLSGDSRLKMRAELGEYIRRITTVPLPTAPNIP-IIDYEVSISGEWSPWQAKVPQIEVETHKVAAPDVVVPTLDTVRHEALLYTWLAEHKPLVLCGPPGSGKTMTLFSALRALPDMEVVGLNFSSATTPELLLKTFDHYCEYRRTPNGVVLAPVQLGKWLVLFCDEINLPDMDKYGTQRVISFIRQMVEHGGFYRTSDQTWVKLERIQFVGACNPPTDPGRKPLSHRFLRHVPVVYVDYPGPASLTQIYGTFNRAMLRLIPSLRTYAEPLTAAMVEFYTMSQERFTQDTQPHYIYSPREMTRWVRGIFEALRPLETLPVEGLIRIWAHEALRLFQDRLVEDEERRWTDENIDTVALKHFPNIDREKAMSRPILYSNWLSKDYIPVDQEELRDYVKARLKVFYEEELDVPLVLFNEVLDHVLRIDRIFRQPQGHLLLIGVSGAGKTTLSRFVAWMNGLSVYQIKVHRKYTGEDFDEDLRTVLRRSGCKNEKIAFIMDESNVLDSGFLERMNTLLANGEVPGLFEGDEYATLMTQCKEGAQKEGLMLDSHEELYKWFTSQVIRNLHVVFTMNPSSEGLKDRAATSPALFNRCVLNWFGDWSTEALYQVGKEFTSKMDLEKPNYIVPDYMPVVYDK-LPQPPSHREAIVNSCVFVHQTLHQANARLAKRGGRTMAITPRHYLDFINHYANLFHEKRSELEEQQMHLNVGLRKIKETVDQVEELRRDLRIKSQELEVKNAAANDKLKKMVKDQQEAEKKKVMSQEIQEQLHKQQEVIADKQMSVKEDLDKVEPAVIEAQNAVKSIKKQHLVEVRSMANPPAAVKLALESICLLLGESTTDWKQIRSIIMRENFIPTIVNFSAEEISDAIREKMKKNYMSNPSYNYEIVNRASLACGPMVKWAIAQLNYADMLKRVEPLRNELQKLEDDAKDNQQKANEVEQMIRDLEASIARYKEEYAVLISEAQAIKADLAAVEAKVNRSTALLKSLSAERERWEKTSETFKNQMSTIAGDCLLSAAFIAYAGYFDQQMRQNLFTTWSHHLQQANIQFRTDIARTEYLSNADERLRWQASSLPADDLCTENAIMLKRFNRYPLIIDPSGQATEFIMNEYKDRKITRTSFLDDAFRKNLESALRFGNPLLVQ 1681
BLAST of Cytoplasmic dynein 1 heavy chain 1 vs. Ensembl Human
Match: DYNC1H1 (dynein cytoplasmic 1 heavy chain 1 [Source:HGNC Symbol;Acc:HGNC:2961]) HSP 1 Score: 2137.46 bits (5537), Expect = 0.000e+0 Identity = 985/1331 (74.00%), Postives = 1158/1331 (87.00%), Query Frame = 3 Query: 7785 DVVVPTMDTVRHEALLYTWLAEHRPVLLCGPPGSGKTMTLFSALRCLPDMEVVGLNFSSATTPELMLKTFDQYCEYRKTPNGIVLAPQQLNKWLIFFCDEINLPDMDKYGTQRVISFLRQMVEHHGFYRITDMQWVSFERIQFVGACNPPTDPGRKPLSHRFLRHVPVVYVDYPGETSLKQIYSTFNRAMLRMLPSLRGYADTLTNAMVEFFLKTQERFTHDMQPHYIYSPREMTRWVRGIHEALKPLESLSVEGLVRIWAHEALRLFQDRLVEEDERHWTDDNINEVALKHFPNINKEEALKRPILYSNWLSKDYSAVTQEELRDYVKARLKVFYEEELDVPLVLFNQVLDHVLRIDRVFRQPQGHLLLIGVSGAGKTTLSRFVSWINGLSVFQVKVHNKYTAEDFDEDLRNVLRRSGCKGEKITFIMDESNVMDSSFLERMNTLLANGEVPGLFEGDELTTLMTQCKEGAIREGLMIDSQEELYKWFTQQICRNLHVVFTMNPSADGLKDKASTSPALFNRCVLNWFGDWSLEAYFQVGKEFTNRLDLERTDYKVPDTLPCIAEGLLPQNPIYRDVVVNALVFVHQTMHQANVRVQKRGGRTAAITPRHYLDLIAHYMKLSAEKRADLEEQQLHLNNGLKKIEQTVDQVEVMQRSLTKKRQELENMNEAANAKLKQMVQDQQEAEQKKTTGQALKEELAKQEQFVNEKQKTVKQELDQVEPTVNEAKQAVQNIRKKDIQEIKAMKNPPNAVKMAVESICLLLGEKTTDWQSILKVIIKDTFVTSILNFNTDDVSDNTRETMKKKYLSNPDYNFEKVNKASNACGPMVKWVLAQISYADILKRVEPLRNELTELSDAAEQNRKKSQETEDLIAQLEKSIAKYTEEYATLISQAQTIKSDLASVESKVGRSVALLGSLSSERTRWDSGSETFKAQMATINGDCLLSSAFMAYGGYFDQHMRTSLFNTWCHHLSEADILFRSDLARVEYLSNPDDRLRWQANSLPADDLCVENAIILRRYNRYPLIIDPSGQATTFLLNEYKEKKITKTSFLDDSFRKTLESALRFGTPLLVQDVESYDPILNPVLNREVRRTGGRTLITLGDQDIDLSPTFTIFLSTRDPSVEFAPDICSRVTFVNFTVTRSSLQNQCLNAVLKIERPDIDQKRSDLLKAQGEFQLKLRHLEKDLLQSLNEAQGNLLENDKIIARLETLKREAADVAKKVEETDVVMQEVESVSTEYVPLAQSCSNIYFTLEAMNQIHFLYQYSLQLMLDIFSSVLINNPELTNVKAASDRLKIITKNLFQVTYNRLARGMLHEDQITFATILARIFLKGS 11777 DVVVPT+DTVRHEALLYTWLAEH+P++LCGPPGSGKTMTLFSALR LPDMEVVGLNFSSATTPEL+LKTFD YCEYR+TPNG+VLAP QL KWL+ FCDEINLPDMDKYGTQRVISF+RQMVEH GFYR +D WV ERIQFVGACNPPTDPGRKPLSHRFLRHVPVVYVDYPG SL QIY TFNRAMLR++PSLR YA+ LT AMVEF+ +QERFT D QPHYIYSPREMTRWVRGI EAL+PLE+L VEGL+RIWAHEALRLFQDRLVE++ER WTD+NI+ VALKHFPNI++E+A+ RPILYSNWLSKDY V QEELRDYVKARLKVFYEEELDVPLVLFN+VLDHVLRIDR+FRQPQGHLLLIGVSGAGKTTLSRFV+W+NGLSV+Q+KVH KYT EDFDEDLR VLRRSGCK EKI FIMDESNV+DS FLERMNTLLANGEVPGLFEGDE TLMTQCKEGA +EGLM+DS EELYKWFT Q+ RNLHVVFTMNPS++GLKD+A+TSPALFNRCVLNWFGDWS EA +QVGKEFT+++DLE+ +Y VPD +P + + L PQ P +R+ +VN+ VFVHQT+HQAN R+ KRGGRT AITPRHYLD I HY L EKR++LEEQQ+HLN GL+KI++TVDQVE ++R L K QELE N AAN KLK+MV+DQQEAE+KK Q ++E+L KQ++ + +KQ +VK++LD+VEP V EA+ AV++I+K+ + E+++M NPP AVK+A+ESICLLLGE TTDW+ I +I+++ F+ +I+NF+ +++SD RE MKK Y+SNP YN+E VN+AS ACGPMVKW +AQ++YAD+LKRVEPLRNEL +L D A+ N++K+ E E +I LE SIA+Y EEYA LIS+AQ IK+DLA+VE+KV RS ALL SLS+ER RW+ SETFK QM+TI GDCLLS+AF+AY GYFDQ MR +LF TW HHL +A+I FR+D+AR EYLSN D+RLRWQA+SLPADDLC ENAI+L+R+NRYPLIIDPSGQAT F++NEYK++KIT+TSFLDD+FRK LESALRFG PLLVQDVESYDP+LNPVLNREVRRTGGR LITLGDQDIDLSP+F IFLSTRDP+VEF PD+CSRVTFVNFTVTRSSLQ+QCLN VLK ERPD+D+KRSDLLK QGEFQL+LR LEK LLQ+LNE +G +L++D II LE LKREAA+V +KVEETD+VMQEVE+VS +Y+PL+ +CS+IYFT+E++ QIHFLYQYSLQ LDI+ +VL NP L V + RL IITK+LFQV +NR+ARGMLH+D ITFA +LARI LKG+ Sbjct: 1 DVVVPTLDTVRHEALLYTWLAEHKPLVLCGPPGSGKTMTLFSALRALPDMEVVGLNFSSATTPELLLKTFDHYCEYRRTPNGVVLAPVQLGKWLVLFCDEINLPDMDKYGTQRVISFIRQMVEHGGFYRTSDQTWVKLERIQFVGACNPPTDPGRKPLSHRFLRHVPVVYVDYPGPASLTQIYGTFNRAMLRLIPSLRTYAEPLTAAMVEFYTMSQERFTQDTQPHYIYSPREMTRWVRGIFEALRPLETLPVEGLIRIWAHEALRLFQDRLVEDEERRWTDENIDTVALKHFPNIDREKAMSRPILYSNWLSKDYIPVDQEELRDYVKARLKVFYEEELDVPLVLFNEVLDHVLRIDRIFRQPQGHLLLIGVSGAGKTTLSRFVAWMNGLSVYQIKVHRKYTGEDFDEDLRTVLRRSGCKNEKIAFIMDESNVLDSGFLERMNTLLANGEVPGLFEGDEYATLMTQCKEGAQKEGLMLDSHEELYKWFTSQVIRNLHVVFTMNPSSEGLKDRAATSPALFNRCVLNWFGDWSTEALYQVGKEFTSKMDLEKPNYIVPDYMPVVYDKL-PQPPSHREAIVNSCVFVHQTLHQANARLAKRGGRTMAITPRHYLDFINHYANLFHEKRSELEEQQMHLNVGLRKIKETVDQVEELRRDLRIKSQELEVKNAAANDKLKKMVKDQQEAEKKKVMSQEIQEQLHKQQEVIADKQMSVKEDLDKVEPAVIEAQNAVKSIKKQHLVEVRSMANPPAAVKLALESICLLLGESTTDWKQIRSIIMRENFIPTIVNFSAEEISDAIREKMKKNYMSNPSYNYEIVNRASLACGPMVKWAIAQLNYADMLKRVEPLRNELQKLEDDAKDNQQKANEVEQMIRDLEASIARYKEEYAVLISEAQAIKADLAAVEAKVNRSTALLKSLSAERERWEKTSETFKNQMSTIAGDCLLSAAFIAYAGYFDQQMRQNLFTTWSHHLQQANIQFRTDIARTEYLSNADERLRWQASSLPADDLCTENAIMLKRFNRYPLIIDPSGQATEFIMNEYKDRKITRTSFLDDAFRKNLESALRFGNPLLVQDVESYDPVLNPVLNREVRRTGGRVLITLGDQDIDLSPSFVIFLSTRDPTVEFPPDLCSRVTFVNFTVTRSSLQSQCLNEVLKAERPDVDEKRSDLLKLQGEFQLRLRQLEKSLLQALNEVKGRILDDDTIITTLENLKREAAEVTRKVEETDIVMQEVETVSQQYLPLSTACSSIYFTMESLKQIHFLYQYSLQFFLDIYHNVLYENPNLKGVTDHTQRLSIITKDLFQVAFNRVARGMLHQDHITFAMLLARIKLKGT 1330
BLAST of Cytoplasmic dynein 1 heavy chain 1 vs. Ensembl Human
Match: DYNC1H1 (dynein cytoplasmic 1 heavy chain 1 [Source:HGNC Symbol;Acc:HGNC:2961]) HSP 1 Score: 1861.66 bits (4821), Expect = 0.000e+0 Identity = 884/1473 (60.01%), Postives = 1132/1473 (76.85%), Query Frame = 3 Query: 9489 LPQNPIYRDVVVNALVFVHQTMHQANVRVQKRGGRTAAITPRHYLDLIAHYMKLSAEKRADLEEQQLHLNNGLKKIEQTVDQVEVMQRSLTKKRQELENMNEAANAKLKQMVQDQQEAEQKKTTGQALKEELAKQEQFVNEKQKTVKQELDQVEPTVNEAKQAVQNIRKKDIQEIKAMKNPPNAVKMAVESICLLLGEKTTDWQSILKVIIKDTFVTSILNFNTDDVSDNTRETMKKKYLSNPDYNFEKVNKASNACGPMVKWVLAQISYADILKRVEPLRNELTELSDAAEQNRKKSQETEDLIAQLEKSIAKYTEEYATLISQAQTIKSDLASVESKVGRSVALLGSLSSERTRWDSGSETFKAQMATINGDCLLSSAFMAYGGYFDQHMRTSLFNTWCHHLSEADILFRSDLARVEYLSNPDDRLRWQANSLPADDLCVENAIILRRYNRYPLIIDPSGQATTFLLNEYKEKKITKTSFLDDSFRKTLESALRFGTPLLVQDVESYDPILNPVLNREVRRTGGRTLITLGDQDIDLSPTFTIFLSTRDPSVEFAPDICSRVTFVNFTVTRSSLQNQCLNAVLKIERPDIDQKRSDLLKAQGEFQLKLRHLEKDLLQSLNEAQGNLLENDKIIARLETLKREAADVAKKVEETDVVMQEVESVSTEYVPLAQSCSNIYFTLEAMNQIHFLYQYSLQLMLDIFSSVLINNPELTNVKAASDRLKIITKNLFQVTYNRLARGMLHEDQITFATILARIFLKGSTPIGFLENEFQHFLRSQEATITSSDSNKQDNLGLTLHQDQIDSVKRLKKLKVFAKIEEKVKSTKDIKNWTLTVTPESNVPELWVDDNNYNDEKLSKIAKGMYNLLIIQAIRPDRLLASTQKFIASVLGDTFTESVRGTLDLASIVEVEVTACVPILLCAVQGYDPSGRVEDLASEQGKQLTGIAIGSAEGFSQAEKAINSAAKTGKWVMLKNVHLATSWLVSLEKKIHSLQAHPNFRLFLTMEITPKLPVNLLRAGRVLVFEPPPGIKANLLRTLSSINNQRMSKEPVERSRLYFLLAWLNAIVQERLRYVPLGYSKKYEFGESDFKCALDTIDTWVDGAAMGRTNLPPEKIPWVALQTLLGSCIYGGKIDNAFDQRLLNSFLGYLFTEKCFDHNFALVSDADDGSNIAFPESTKHTDILQWVHKLPDLQTPSWLGLPNSAEKVLLTNLGQSLIGNILKMQQSLEDDEELVVGQSKTK-RTIEVGDGRPAWMRQLYQSTQTWLQILPKSVTPLQRTIENIKDPMYRCFEREVNSGCNLLASVRKDLEDVAEVCKGAKKPTNHHRSMMADLAKGIIPKMWIRYAIPPGLTVIQWIQDFADRIKQLLHISDTAAKSGVIALRSIQVWLGGLFMAEAYITATRQSVAQNNKWALEELFLDVELGEGK---VDSNTCVITGLRLMGSEIVDPRTLKLSTLIYKDIDICRLKWIR 13895 LPQ P +R+ +VN+ VFVHQT+HQAN R+ KRGGRT AITPRHYLD I HY L EKR++LEEQQ+HLN GL+KI++TVDQVE ++R L K QELE N AAN KLK+MV+DQQEAE+KK Q ++E+L KQ++ + +KQ +VK++LD+VEP V EA+ AV++I+K+ + E+++M NPP AVK+A+ESICLLLGE TTDW+ I +I+++ F+ +I+NF+ +++SD RE MKK Y+SNP YN+E VN+AS ACGPMVKW +AQ++YAD+LKRVEPLRNEL +L D A+ N++K+ E E +I LE SIA+Y EEYA LIS+AQ IK+DLA+VE+KV RS ALL SLS+ER RW+ SETFK QM+TI GDCLLS+AF+AY GYFDQ MR +LF TW HHL +A+I FR+D+AR EYLSN D+RLRWQA+SLPADDLC ENAI+L+R+NRYPLIIDPSGQAT F++NEYK++KIT+TSFLDD+FRK LESALRFG PLLVQDVESYDP+LNPVLNREVRRTGGR LITLGDQDIDLSP+F IFLSTRDP+VEF PD+CSRVTFVNFTVTRSSLQ+QCLN VLK ERPD+D+KRSDLLK QGEFQL+LR LEK LLQ+LNE +G +L++D II LE LKREAA+V +KVEETD+VMQEVE+VS +Y+PL+ +CS+IYFT+E++ QIHFLYQYSLQ LDI+ +VL NP L V + RL IITK+LFQV +NR+ARGMLH+D ITFA +LARI LKG+ + EFQHFLR E +++ + + GLT+ +Q ++V RL L F + KV++ + W + +PE VP LW ++ + I + ++ LL+IQA RPDRLLA F+++ LG++F + LDL IV EV P+L+C+V GYD SG VEDLA+EQ Q+T IAIGSAEGF+QA+KAIN+A K+G+WVMLKNVHLA WL+ LEKK+HSLQ H FRLFLTMEI PK+PVNLLRAGR+ VFEPPPG+KAN+LRT SSI R+ K P ER+RLYFLLAW +AI+QERLRY PLG+SKKYEFGESD + A DT+DTW+D A GR N+ P+KIPW AL+TL+ IYGG++DN FDQRLLN+FL LFT + FD F L D +I P+ + + +QWV LPD QTPSWLGLPN+AE+VLLT G +I +LKMQ LED+++L +++ K RT DGRPAWMR L+ + WL ++P++++ L+RT+ENIKDP++R FEREV G LL VR+DL DV +VC+G KK TN+ R+++ +L KGI+P+ W Y +P G+TVIQW+ DF++RIKQL +IS AA G L++I V LGGLF+ EAYITATRQ VAQ N W+LEEL L+V + + +D+ + +TGL+L G+ + L LS I + + +L+W++ Sbjct: 5 LPQPPSHREAIVNSCVFVHQTLHQANARLAKRGGRTMAITPRHYLDFINHYANLFHEKRSELEEQQMHLNVGLRKIKETVDQVEELRRDLRIKSQELEVKNAAANDKLKKMVKDQQEAEKKKVMSQEIQEQLHKQQEVIADKQMSVKEDLDKVEPAVIEAQNAVKSIKKQHLVEVRSMANPPAAVKLALESICLLLGESTTDWKQIRSIIMRENFIPTIVNFSAEEISDAIREKMKKNYMSNPSYNYEIVNRASLACGPMVKWAIAQLNYADMLKRVEPLRNELQKLEDDAKDNQQKANEVEQMIRDLEASIARYKEEYAVLISEAQAIKADLAAVEAKVNRSTALLKSLSAERERWEKTSETFKNQMSTIAGDCLLSAAFIAYAGYFDQQMRQNLFTTWSHHLQQANIQFRTDIARTEYLSNADERLRWQASSLPADDLCTENAIMLKRFNRYPLIIDPSGQATEFIMNEYKDRKITRTSFLDDAFRKNLESALRFGNPLLVQDVESYDPVLNPVLNREVRRTGGRVLITLGDQDIDLSPSFVIFLSTRDPTVEFPPDLCSRVTFVNFTVTRSSLQSQCLNEVLKAERPDVDEKRSDLLKLQGEFQLRLRQLEKSLLQALNEVKGRILDDDTIITTLENLKREAAEVTRKVEETDIVMQEVETVSQQYLPLSTACSSIYFTMESLKQIHFLYQYSLQFFLDIYHNVLYENPNLKGVTDHTQRLSIITKDLFQVAFNRVARGMLHQDHITFAMLLARIKLKGTVGEPTYDAEFQHFLRGNEIVLSAGSTPRIQ--GLTV--EQAEAVVRLSCLPAFKDLIAKVQADEQFGIWLDSSSPEQTVPYLWSEET-----PATPIGQAIHRLLLIQAFRPDRLLAMAHMFVSTNLGESFMSIMEQPLDLTHIVGTEVKPNTPVLMCSVPGYDASGHVEDLAAEQNTQITSIAIGSAEGFNQADKAINTAVKSGRWVMLKNVHLAPGWLMQLEKKLHSLQPHACFRLFLTMEINPKVPVNLLRAGRIFVFEPPPGVKANMLRTFSSIPVSRICKSPNERARLYFLLAWFHAIIQERLRYAPLGWSKKYEFGESDLRSACDTVDTWLDDTAKGRQNISPDKIPWSALKTLMAQSIYGGRVDNEFDQRLLNTFLERLFTTRSFDSEFKLACKVDGHKDIQMPDGIRREEFVQWVELLPDTQTPSWLGLPNNAERVLLTTQGVDMISKMLKMQM-LEDEDDLAYAETEKKTRTDSTSDGRPAWMRTLHTTASNWLHLIPQTLSHLKRTVENIKDPLFRFFEREVKMGAKLLQDVRQDLADVVQVCEGKKKQTNYLRTLINELVKGILPRSWSHYTVPAGMTVIQWVSDFSERIKQLQNISLAAASGGAKELKNIHVCLGGLFVPEAYITATRQYVAQANSWSLEELCLEVNVTTSQGATLDACSFGVTGLKLQGA-TCNNNKLSLSNAISTALPLTQLRWVK 1466
BLAST of Cytoplasmic dynein 1 heavy chain 1 vs. Ensembl Celegans
Match: dhc-1 (Dynein heavy chain, cytoplasmic [Source:UniProtKB/Swiss-Prot;Acc:Q19020]) HSP 1 Score: 4838.09 bits (12548), Expect = 0.000e+0 Identity = 2390/4571 (52.29%), Postives = 3230/4571 (70.66%), Query Frame = 3 Query: 384 FESNKSQTSIFIKNNQVIEADKTISSQLQVLSYCDGPPFETMHSLVCYGLLPYFXXXXXXXXXXXXXXXXXMVPSVEKKIAELEIGLLHLQQNIEIPEITLTPHPYVAHIIQEKLLQNKEARVSDFEDKFEDTQFLNQLQAGVNRWIKEIQKVTKLNRDPSTGTALQEISFWLNLEHSLDKIQEKRESLEVALTLAILKQAKRFHATTSFDTDTALSSAKIQVKDYNQLMKDFPINDLLSASQLDKISEALQQIFSHLKKVRATKYPVNRIIKLMEALSRDLTTQLMKVISNMHLMSMPYDEFEKIFTACQQVFSTWEDEYDKMQNLLRDIAKKKREEFTKFAWKMNATHKKLQTRLENIKKFRYQHEQLRQVIVRVLKPVTKVVPSVEAGVPKDQI---TDKGDKSSTFLPESADTSSIDEVNAAYEIVKVIDCLDFAKEENDEWDAAIKRYEERIDRVESRIASHLRDLLGQSKNANEMFRYFSRFNALFVRPHIRGAIGEYQTQLIQRVKDDIEALHNKFKVQYASSTACKMSKVRDLPPVSGSIIWVRQILRQLNAYMKRVEDVLGKDWAQHIEGQKLKADGESFKLKLNTSELFEEWSKKVAEKSLSVAGSIFNVESTRTVVTVRDREPQKITVLKLKVNFLPDVITLAKEVRNMRALGFRTPLSIVNKAHSANQLYPFAISLIESVRTYESTCSKIEEHKMQNISLLTAGLRKDVQLCIHEGVQITWESYRLDQYVQKLAELVFSFQEKVDDLVIVIKEIDFNVKALETCSYNKQTFEEILIRIQEAVDNMSLHQFSNLAQWVSNLDSLVEQRLIVRLEAGLLEWIKVLKGXXXXXXXXXXXXXXXVNSMAKHRLGGKPQIKKLIHELRITNQQMHLYPSIEVATQDILYQMSSWQNIILNLSRIVHSRYQVGLETESDNQKTYKKLLSSLPNSGESLENAYAAVHNILRDANEYVKTWTNYQSLWDLQGDQLFSLIADDNTVWMNVLEEIKSMRKHFDVAETQKEFGPLVIAFGKVQSKVSMKYDNWHKEVLTKFGQNMGKMMTTLYNEVQRARNELEQQSIDSGGTNESVNFITYTQNIKRKMNTWEKQAEACRAGQNILCRDRFQFPNDWLDSENIQGEWSAFKEIMRRKQETISSQVASLQMKITEEDKIVESKTTEVLGNWEKDKPIAGDLTPEEAVNIIQILEGKFNRLKEERENVQKAKEALELTEIGVKPISEEKVTNALSELHDLKNVWNELKSIWEKIRDMKETPWLSVQPRKLRQDIENLTAQLKELPNSFKQYASFEHVRTLLKMYMKVNASIVELKSEAIKERHWRMLMRKLNVSWSLNELQLGKVWDIDLVKNEEIIREVLAIAQGEKALEEYLRQITEVWKNYVLELTNYQSKSKIIKGWDDLFNKVKEHINNVTSMKASPYFKQFEEEATAWEDRLNKINALFDVWIDVQRRWIYLDGIFAGSADIKVLLPVESQRFQSVSTEFLGLMKKVQKSPLVTDVLNIANVQRQLERLADLLGKIQKSLGEYLERQRSSFPRFYFVGDEDLLEIIGNSXXXXXXXXXXXXMFAGVHSIILSEDEKVILGMMSKEGEELRFISPVSIIEHPRINDWLTAMEKEMRVSLAKYLNVAVKEISGWRTESNIDKDKFMVWLDKYQAQIVVLAAQITWSEAVEASLASGVSLESTMTVVHSTLNMLADTVLYEQPPVRRRKLEHLIIEYVHQRDVLRALHNDGVSSNKNFDWMSQMRFYFDPKQTDPLHQLSIHVANAKFHYGFEYLGVCDRLVQTPLTDRCYLTMTQALEARLGGSPFGPAGTGKTESVKSLGNQLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLSAVSQQIQGIQEALRELMVSKKDSINVELLGKQVHVNPDMAIFITMNPGYAGRSNLPDNLKKLFRSLAMTQPDRQLIAQVMLYSQGFRTAEVLAGKVVPFFKLCDEQLSPQSHYDFGLRALKSVLVSAGNVKRDRIKQEKEKIVARGEEINETAIAEQLPEQEILIQSVMETMVPKLIADDIPLLYSLLTDVFPGVEYRQAEMKRLREELRKVSENKFLVYSDEPNTAGYLWVEKVLQLYQITTIHHGLMMVGPSGSGKTMACRVLLQALENIDGIEGVAHIIDPKSISKDSLYGYMDPNTREWTDGLFTHILRRIIDSVRGESNKRQWIVFDGDVDPEWVENLNSVLDDNKLLTLPNGERLAIPPNVRIMFEVQDLKYATLATVSRCGMVWFSEEVLTTGMILTHFLNELKKVQVMEGEEDFSVNQGD----TGADADSKISSSPIIQLQTQVSSILAPFFTEDGLIAKCLDYSTT-LEHIMDFTRLRALTSLFSMIKQSIRNMIEYNQSHSDFPLNNEQIENYVAKSLISSVVWSMSGDSKLKVREQLSQYIKNISTVDLPTVGGIKNIIDFEVNIQGTWVAWSNKVPQIEVETHKITATDVVVPTMDTVRHEALLYTWLAEHRPVLLCGPPGSGKTMTLFSALRCLPDMEVVGLNFSSATTPELMLKTFDQYCEYRKTPNGIVLAPQQLNKWLIFFCDEINLPDMDKYGTQRVISFLRQMVEHHGFYRITDMQWVSFERIQFVGACNPPTDPGRKPLSHRFLRHVPVVYVDYPGETSLKQIYSTFNRAMLRMLPSLRGYADTLTNAMVEFFLKTQERFTHDMQPHYIYSPREMTRWVRGIHEALKPLESLSVEGLVRIWAHEALRLFQDRLVEEDERHWTDDNINEVALKHFPNINK-EEALKRPILYSNWLSKDYSAVTQEELRDYVKARLKVFYEEELDVPLVLFNQVLDHVLRIDRVFRQPQGHLLLIGVSGAGKTTLSRFVSWINGLSVFQVKVHNKYTAEDFDEDLRNVLRRSGCKGEKITFIMDESNVMDSSFLERMNTLLANGEVPGLFEGDELTTLMTQCKEGAIREGLMIDSQEELYKWFTQQICRNLHVVFTMNPSADGLKDKASTSPALFNRCVLNWFGDWSLEAYFQVGKEFTNRLDLERTDYKVPDTLPCIAEGLLPQNPIYRDVVVNALVFVHQTMHQANVRVQKRGGRTAAITPRHYLDLIAHYMKLSAEKRADLEEQQLHLNNGLKKIEQTVDQVEVMQRSLTKKRQELENMNEAANAKLKQMVQDQQEAEQKKTTGQALKEELAKQEQFVNEKQKTVKQELDQVEPTVNEAKQAVQNIRKKDIQEIKAMKNPPNAVKMAVESICLLLGEKT-TDWQSILKVIIKDTFVTSILNFNTDDVSDNTRETMKKKYLSNPDYNFEKVNKASNACGPMVKWVLAQISYADILKRVEPLRNELTELSDAAEQNRKKSQETEDLIAQLEKSIAKYTEEYATLISQAQTIKSDLASVESKVGRSVALLGSLSSERTRWDSGSETFKAQMATINGDCLLSSAFMAYGGYFDQHMRTSLFNTWCHHLSEADILFRSDLARVEYLSNPDDRLRWQANSLPADDLCVENAIILRRYNRYPLIIDPSGQATTFLLNEYKEKKITKTSFLDDSFRKTLESALRFGTPLLVQDVESYDPILNPVLNREVRRTGGRTLITLGDQDIDLSPTFTIFLSTRDPSVEFAPDICSRVTFVNFTVTRSSLQNQCLNAVLKIERPDIDQKRSDLLKAQGEFQLKLRHLEKDLLQSLNEAQGNLLENDKIIARLETLKREAADVAKKVEETDVVMQEVESVSTEYVPLAQSCSNIYFTLEAMNQIHFLYQYSLQLMLDIFSSVLINNPELTNVKAASDRLKIITKNLFQVTYNRLARGMLHEDQITFATILARIFLKGSTPIGFLENEFQHFLRSQEATITSSDSNKQDNLGLT-LHQDQIDSVKRLKKL----KVFAKIEEKVKSTKDIKNWTLTVTPESNVPELWVDDNNYNDEKLSKIAKGMYNLLIIQAIRPDRLLASTQKFIASVLGDTFTESVRGTLDLASIVEVEVTACVPILLCAVQGYDPSGRVEDLASEQGKQLTGIAIGSAEGFSQAEKAINSAAKTGKWVMLKNVHLATSWLVSLEKKIHSLQAHPNFRLFLTMEITPKLPVNLLRAGRVLVFEPPPGIKANLLRTLSSINNQRMSKEPVERSRLYFLLAWLNAIVQERLRYVPLGYSKKYEFGESDFKCALDTIDTWVDGAAMGRTNLPPEKIPWVALQTLLGSCIYGGKIDNAFDQRLLNSFLGYLFTEKCFDHNFALVSDADDGSNIAFPESTKHTDILQWVHKLPDLQTPSWLGLPNSAEKVLLTNLGQSLIGNILKMQQSLEDDEELVVGQSKTKRTIEVGDGRPAWMRQLYQSTQTWLQILPKSVTPLQRTIENIKDPMYRCFEREVNSGCNLLASVRKDLEDVAEVCKGAKKPTNHHRSMMADLAKGIIPKMWIRYAIPPGLTVIQWIQDFADRIKQLLHISDTAAKSGVIALRSIQVWLGGLFMAEAYITATRQSVAQNNKWALEELFLDVELGEGKVDSNTCV-ITGLRLMGSEIVDPRTLKLSTLIYKDIDICRLKWIRVEKSQQLEGSSAKDKVCLPIYLNAARSTVLFTLYFSTTDSSYDFYKRGVAI 14048 F +++ Q +F+K + VIEA+K I++Q+ G +E +H L+ L PY DK+ P+V+K E E LLHLQQNI+IPEI L + ++ I++ +N+ A++ D D ED FLN LQ+G NRW+KEI+KVT+L RDPS+GT+LQE++FWLNLE +L KI +KR+ EV LTL LK KRFHAT FD+D L V+DYN LMK+FP+++L+SA+ + K+ A+ IF HL+K+R+TKYP+ R ++L+EA+SRDL +QL+KV+S+ +LM P EF +I + CQ +FS W+DEYDK LLRDI KKKR++ +K +WK+ A HK+L+TRL I +FR QHEQ R VI RVL+PV ++Q+ + +G+KS P+ ++V+ AYE +K +D LD ++ W+ A KRYE++I VE+ I + L+ L S+N+NEMF FSR+NALF+RP IRGAI EYQT+LI RVK+DI L +F + K+ + LPP S I+W+R RQL YMKRVEDVLGK W H++G++LKADG++FK+KLNT +F+EW + V ++ ++ I V+ R V R + L+LK+N+ D L KEV +++++GFR PL IVN AH ANQ+ P A SLIE+ RT+ S + + +Q + L A +KD+Q + EG + W+SY++DQY KLAE V ++QE+ ++L+ V++ ++ ++ L++C Y+K+T E +L IQ+ VD +SL +SNLAQWV+ LD +E L R+E + W V +E + R P +K ++ +L +T Q +++ PS + IL Q+ W ++ RI R+Q+ + E + + TY +L+ +P LE AY V+ I+ D EY+ W +YQSLW LQ +QLF ++ + WM L EI+ R FD +T+K P+ + +GK Q K+ KYD WHKE+L KFG +G M +N V + RN LE QS+D G T++++ I++ Q++K++ + + + R+ Q +L + R+QFP WL SEN++GEWSAF EI+ + +I +Q+ +LQ K +ED++VE +T E L W K KP+ G P+EA+N+I E K N+L EER ++KA+ AL+L++ P +K+T A EL +K+VW L+ ++ I + KE WLSVQPRK+RQ ++ L QLK+LP + Y S+EHV+ +L Y K+N + ELKSEA+KERHW +M+++ V+W+L++L LG+VWD D++++E I+++L +AQGE ALEE+LR++ E W+NY +EL NYQ+K+++IKGWDDLFNK+KEH N++++MK SPY+KQFEE A +W+++LNKINA+FDVWIDVQRRW+YL+G+F+GSA+I LLP ES RF +++T+ L LMKKV SP + DV+N+ QR LERLAD+L KIQK+LGEYLER+RSSFPRFYFVGDEDLLEI+GNSKD+ ++QKH KKMFAG+ +I ++E+++ I S+EGE++ + VS + RINDWL A+E EM+ +LA+ L ++ S ++ + D ++ WLDK+ AQ++ L A+I W + +E +LA G E+ V TL +LAD+VL EQPP+RR+K+E LI E VH+RD R L + + + +F W+ MRFYFDPKQ DP+ + +AN++F YGFEYLG+ +RLV+TPLTDRCYLTMTQAL +RLGGSPFGPAGTGKTESVK+LG+QLGRFVLVFNCDETFDFQAMGRI VGLCQVGAWGCFDEFNRLEERMLSAVSQQIQ IQEA+R ++V+L+GK+++VN ++ IFITMNPGY+GRSNLPDNLK+LFRSLAMTQPDRQLIAQVML+SQGFRTAE LA K+VP F LC EQLS Q HYDFGLRALK VLVSAGN+KRD++ + +A E + EQ++LIQSV ET+VPKL+ +DI LL+SLL+DVFPG+ Y +M+ LR++L V + L+YSD G +W++KVLQLYQIT ++HGLM+VG SGSGKTMA +VLL+ALE + +EGVAH+ID K++SKDSLYG MDPNTREWTDGLFT ++R+IID+VRGE+++RQWI+FDGDVDPEWVENLNSVLDDNKLLTLPNGERL+IPPNVRI+FEV DLKYATLATVSRCGMVWFSEEV+T+ M+ +L+ +++V + + G DA S I++Q + L F+ DG++ L Y+ + LEHIM T R L+S FSM+ SIR ++ +++ D + +QI+++V +S+++++VW+ SGD K K RE +S +I+ +T+ LP +ID+EV + G W W +KVP +E+E+H++ A D+VVPT+DTVRHE LL WLAEH+P++LCGPPGSGKTMTL +ALR +MEVV +NFSS+TTPEL+L+TFD YCEYR+TPNG+VLAP QL++WL+ FCDEINLP DKYGTQRVISFLRQ+VE +GFYR +D WVS ERIQFVGACNPPTDPGR P++ RFLRHVP+VYVDYPG+TSL+QIY TFNRAML+M P++RG AD LTNAMV+ +L +QE FT D QPHY+YSPRE+TRWVRGI EA+ PLESLS E LVR+WAHEA+RLFQDRLV E+ER WTD ++ A ++F N + +EALKRP+LYS WLS++Y VT+EEL+DYV ARLK FYEEELDV LVLF+Q+LDHVLRIDR++RQ QGHLLLIG +GAGKTTLSRFV+W+NGLSVFQ+KVH+KYTA DFDED+R VLRR+GC+ EK+ FIMDESN++D+ FLER+NTLLANGEVPGLFEGDE TTLMTQ KEGA R+GL++DS +ELYKWFTQQ+ RNLHVVFTMNPS GL+++ASTSPALFNRCVLNWFGDWS A +QVG E T +DL+RTDY+ L E L+P P YRD VVN L VH+T+ + N K+G R A TPRH+LD I +M L EKR+DLEE+++HLN GL KI +T +QV+ +Q+SL K EL+ EAAN KLK+M+ DQQ+AE++K + L++ELA+Q + + EK+ V+ +L QVEP V EA+ AVQ I+K + E+K+M +PP VK+ +E+IC+LLGE TDW++I +V++KD F+T IL F+T+ ++ + M +KY+ NPD+ F+KVN+AS ACGPMVKW AQ+ Y+ +L +VEPLRNEL L A + ++ + + I +LE+SI KY EEYA LI QA+ IK DL SV+ KV RS LL SL SER RW SGS F QM ++ GD LLSSAF+AY GY+DQ +R +F+ W +H+ A + FR DLAR+EYLS DDRL+WQ NSLP DDLC ENAI+L R+NRYPLIIDPSGQA +++ ++ K I KTSFLD+SFRK LESALRFG LLVQDVE+YDPILNPVLNREV+R GGR LIT+GDQDIDLSP+F IF+ TRD +VEF+PDICSRVTFVNFTVT SSL +QCLN VL+ ERPD+D+KR+DLLK QGEF ++LRHLEK LL +LNE++G +L+++ +I LE LK EAA+VA+K ETD VM EV++VS +Y L+ +CS+IY TL+ +N+IHFLY YSL +++IF+ VL PEL++ + RL+IIT +LFQ + R++RGMLH D++ A +L RI ++ + E F L + + +++ GL L + S+ + +K+ VFA ++ ++ + +W PESNVP +W D D KLS + M +L+++ A+RPDRL+AS + +++ D F + + +D+ SIV+ EV+ P+LLC+ GYD SG++EDLA E +QLT IAIGSAEGF+QA+ A+ +A K+G+WV+LKNVHLA SWL LEK++HS++ H FRLFLT EI PKLP ++LRA RV+VFEP G+KANLLR+LSSI QR++K P ERSRLY L+ WL+A+VQERLRY PLG+S YEF ++D + A DT+D VD A GR N+ PE++PW L+TLL CIYGGKIDN FDQ LL+ L LFT K F+ + L+ D ++ P +K ++ WV +L + Q P+WLGLPN+AEKVLLT G+S++ N+LK+ DEEL + + +P WM QL + + WLQ+LPK + ++RT+ENIKDP++R FEREVN G LL +R+DL +++ VC+ KK N R++ A L KG +P W RY +P +TV+ W+ D +R+KQL+ I G L+ WLGG F EAYITATRQ VAQ N W+LE+L L + + G+ DS I+G+ + G++ V L+L L+ + DI W D LP+YL R ++ L F + ++ FY+RGVA+ Sbjct: 104 FMTDRGQAMMFVKQSNVIEAEKKIATQVSAFPLNGGSAWEQLHFLMSRLLNPY-CKSFIGQSGRGERDGDKLAPTVQKCFTEAEAALLHLQQNIDIPEINLVVNQHILDAIEQAGKENRRAKIEDLGDLVEDANFLNALQSGCNRWVKEIRKVTQLERDPSSGTSLQEMTFWLNLERALLKISQKRDGEEVTLTLEALKCGKRFHATVGFDSDNGLKQKLAVVQDYNTLMKEFPLSELVSATDVPKLMHAVVGIFLHLRKLRSTKYPLQRALRLVEAISRDLNSQLLKVLSSYNLMRTPIAEFNEIMSQCQALFSKWDDEYDKFIALLRDINKKKRDDPSKLSWKVTAVHKRLETRLMQILQFRKQHEQFRTVIERVLRPVGN------GSREREQLMIDSSEGEKS----PD-------EQVDIAYEFLKNVDFLDV---DSPAWENAFKRYEDQIGVVETAITTRLKSQLESSRNSNEMFSIFSRYNALFIRPRIRGAIYEYQTRLINRVKEDINELQARF-TKARGEQGVKIMQTVGLPPFSAKIMWIRNYERQLQRYMKRVEDVLGKQWENHVDGRQLKADGDNFKVKLNTQPMFDEWVESVQSQNWTLPNKILTVD--RVQVDGRMQ-------LQLKINYHSDSSVLYKEVSHLKSMGFRVPLKIVNWAHQANQMRPSATSLIEAARTFASVNAALA--SVQGVDSLLASYKKDIQNQLIEGATLGWDSYKVDQYQLKLAETVNTYQERCEELLNVVRIVNADLNVLKSCRYDKETIENLLTSIQKGVDQLSLGNYSNLAQWVNTLDRQIETILARRVEDAIRVWTLVFSQSEEVEEL-------------RERQVVLPTVKNVVVDLCMTAQTLYISPSTRETREKILEQLYEWHSVCTAQMRISGKRFQMVMNEEIEPE-TYHNILNVMPEGQACLEKAYDCVNGIMSDLEEYLSEWLSYQSLWVLQAEQLFEMLGTSLSKWMKTLMEIRKGRLVFDTQDTRKVIFPVSVEYGKAQQKILFKYDYWHKEMLVKFGAVVGDEMQKFFNSVSKWRNVLETQSVDGGSTSDTIGLISFVQSLKKQTKSGQDAVDLYRSSQRLLNQQRYQFPAQWLYSENVEGEWSAFTEILSLRDASIQTQMMNLQTKFAQEDELVEKRTVETLTEWNKSKPVEGAQRPQEALNVITAFEAKLNKLTEERNKMRKARVALDLSDSAHAPSEGDKLTVATEELAAMKDVWKALQPVYTGIDEAKEKTWLSVQPRKIRQSLDELMNQLKQLPVKCRTYKSYEHVKQMLHTYGKMNMLVAELKSEALKERHWHQMMKEMRVNWNLSDLTLGQVWDADILRHEHTIKKILLVAQGEMALEEFLREMREYWQNYEVELVNYQNKTRLIKGWDDLFNKLKEHQNSLSAMKLSPYYKQFEESAQSWDEKLNKINAMFDVWIDVQRRWVYLEGLFSGSAEISTLLPFESSRFATITTDVLALMKKVAASPRILDVVNMQGAQRLLERLADMLAKIQKALGEYLERERSSFPRFYFVGDEDLLEIMGNSKDITRIQKHLKKMFAGITAIDINEEDRSITAFHSREGEKVDLVKIVS-TKDVRINDWLQALEAEMKHTLARQLAASLTHFSKMNIQT-MTTDDYVEWLDKFPAQVITLTAEIWWCDEMEKTLADGKGAENVEQAVVKTLELLADSVLKEQPPIRRKKMEALITELVHKRDTCRKLVSMKIRAANDFGWLQCMRFYFDPKQVDPVRCCVVKMANSQFFYGFEYLGIQERLVRTPLTDRCYLTMTQALHSRLGGSPFGPAGTGKTESVKALGHQLGRFVLVFNCDETFDFQAMGRILVGLCQVGAWGCFDEFNRLEERMLSAVSQQIQTIQEAVR-----AGGDMSVDLVGKRLNVNSNIGIFITMNPGYSGRSNLPDNLKQLFRSLAMTQPDRQLIAQVMLFSQGFRTAETLANKIVPLFILCKEQLSDQCHYDFGLRALKYVLVSAGNIKRDKLDKMG------------SAALEDVAEQQMLIQSVCETLVPKLVNEDIALLFSLLSDVFPGIHYTANQMRELRQQLSTVCDEHLLIYSDVQGEMGSMWLDKVLQLYQITNLNHGLMLVGSSGSGKTMAWKVLLKALERWENVEGVAHVIDAKAMSKDSLYGVMDPNTREWTDGLFTSVIRKIIDNVRGEADRRQWIIFDGDVDPEWVENLNSVLDDNKLLTLPNGERLSIPPNVRIIFEVADLKYATLATVSRCGMVWFSEEVVTSEMLFERYLSIIRRVPLDSDSAISFSSSSAPVNLIGEDAKPTRS----IEIQRTAALALQTHFSPDGIVPGSLKYAVSELEHIMPPTPQRLLSSFFSMMSYSIRKIVSHDEGLIDDSVEIDQIQSFVLRSMLTNLVWAFSGDGKWKSREMMSDFIRQATTISLPP-NQQACLIDYEVQLSGDWQPWLSKVPTMEIESHRVAAADLVVPTIDTVRHEMLLAAWLAEHKPLVLCGPPGSGKTMTLLAALRSQQEMEVVNVNFSSSTTPELLLRTFDHYCEYRRTPNGVVLAPVQLSQWLVIFCDEINLPAPDKYGTQRVISFLRQLVELNGFYRTSDHSWVSLERIQFVGACNPPTDPGRHPMTSRFLRHVPIVYVDYPGQTSLQQIYGTFNRAMLKMTPAVRGLADQLTNAMVDVYLASQEHFTQDDQPHYVYSPRELTRWVRGISEAITPLESLSAEQLVRLWAHEAIRLFQDRLVTEEEREWTDKLVDTTAERYFGNACRLDEALKRPLLYSCWLSRNYVPVTREELQDYVSARLKGFYEEELDVKLVLFDQMLDHVLRIDRIYRQSQGHLLLIGTAGAGKTTLSRFVAWLNGLSVFQLKVHSKYTAADFDEDMRTVLRRAGCRNEKLCFIMDESNMLDTGFLERLNTLLANGEVPGLFEGDEHTTLMTQIKEGAQRQGLILDSHDELYKWFTQQVMRNLHVVFTMNPSGSGLRERASTSPALFNRCVLNWFGDWSENALYQVGSELTRTMDLDRTDYEGSVRLTPSCE-LVPSQPTYRDAVVNTLCLVHKTVQKFNEMETKKGHRVMACTPRHFLDFIKQFMSLFHEKRSDLEEEKIHLNIGLNKISETEEQVKELQKSLKLKSNELQEKKEAANLKLKEMLGDQQKAEEEKKFSEQLQKELAEQLKQMAEKKTFVENDLAQVEPAVAEAQTAVQGIKKSQLVEVKSMSSPPVTVKLTLEAICILLGENVGTDWKAIRQVMMKDDFMTRILQFDTELLTPEILKQM-EKYIQNPDWEFDKVNRASVACGPMVKWARAQLLYSTMLHKVEPLRNELKRLEQEAAKKTQEGKVVDVRITELEESIGKYKEEYAQLIGQAENIKQDLLSVQEKVNRSTELLSSLRSERDRWSSGSAGFSQQMDSLVGDALLSSAFLAYAGYYDQMLRDEIFHKWFNHVVNAGLHFRHDLARIEYLSTVDDRLQWQLNSLPVDDLCTENAIMLHRFNRYPLIIDPSGQAVEYIMKQFAGKNIQKTSFLDESFRKNLESALRFGNSLLVQDVEAYDPILNPVLNREVKRAGGRVLITIGDQDIDLSPSFQIFMITRDSTVEFSPDICSRVTFVNFTVTSSSLASQCLNQVLRSERPDVDKKRNDLLKLQGEFAVRLRHLEKALLAALNESKGKILDDNSVIETLEKLKNEAAEVAQKSAETDKVMAEVDAVSAQYQRLSTACSHIYHTLQQLNEIHFLYHYSLDFLVEIFTHVL-KTPELSSTTDYAKRLRIITTSLFQTVFRRVSRGMLHTDKVLLALLLMRIHIRSNPSAPAYEQHFDLLLGRSDFVAKNDEADSTIPGGLDFLTVENKKSIAKARKVVGFENVFAHLQH---NSAAVTSWLTNDNPESNVPVVWDD----ADGKLSPLCIAMNSLIVVHALRPDRLMASAHRVVSTAFDDHFMQQDK-VVDILSIVDNEVSPSEPVLLCSATGYDASGKIEDLAVETNRQLTSIAIGSAEGFNQADSALGTATKSGRWVLLKNVHLAPSWLAQLEKRLHSMKPHAQFRLFLTAEIHPKLPSSILRASRVVVFEPATGLKANLLRSLSSIPPQRLTKAPTERSRLYLLVCWLHALVQERLRYTPLGWSTAYEFSDADLRVACDTLDAAVDAVAQGRPNVEPERLPWTTLRTLLSQCIYGGKIDNQFDQVLLDCVLENLFTAKSFEQDHVLIPKYDGDDSLFTPNMSKKDQMIGWVEELKNEQLPAWLGLPNNAEKVLLTKRGESMLRNMLKVT-----DEELAFNEDGKEEV------KPQWMAQLGELAKQWLQLLPKEIVKMRRTVENIKDPLFRFFEREVNLGSQLLKDIRRDLNEISAVCRAEKKQNNETRALAASLQKGEVPTGWKRYTVPREVTVMDWMTDLNERLKQLIRI------GGADNLKRETFWLGGTFSPEAYITATRQQVAQANTWSLEQLNLHIHI--GRTDSTDVFRISGIDIRGAKSVGGNKLELCELVKSECDIVEFSW----------KQDVADGTRLPLYLYGDRRQLISPLAFHLSSATV-FYQRGVAL 4562
BLAST of Cytoplasmic dynein 1 heavy chain 1 vs. Ensembl Celegans
Match: dhc-1 (Dynein heavy chain, cytoplasmic [Source:UniProtKB/Swiss-Prot;Acc:Q19020]) HSP 1 Score: 4838.09 bits (12548), Expect = 0.000e+0 Identity = 2390/4571 (52.29%), Postives = 3230/4571 (70.66%), Query Frame = 3 Query: 384 FESNKSQTSIFIKNNQVIEADKTISSQLQVLSYCDGPPFETMHSLVCYGLLPYFXXXXXXXXXXXXXXXXXMVPSVEKKIAELEIGLLHLQQNIEIPEITLTPHPYVAHIIQEKLLQNKEARVSDFEDKFEDTQFLNQLQAGVNRWIKEIQKVTKLNRDPSTGTALQEISFWLNLEHSLDKIQEKRESLEVALTLAILKQAKRFHATTSFDTDTALSSAKIQVKDYNQLMKDFPINDLLSASQLDKISEALQQIFSHLKKVRATKYPVNRIIKLMEALSRDLTTQLMKVISNMHLMSMPYDEFEKIFTACQQVFSTWEDEYDKMQNLLRDIAKKKREEFTKFAWKMNATHKKLQTRLENIKKFRYQHEQLRQVIVRVLKPVTKVVPSVEAGVPKDQI---TDKGDKSSTFLPESADTSSIDEVNAAYEIVKVIDCLDFAKEENDEWDAAIKRYEERIDRVESRIASHLRDLLGQSKNANEMFRYFSRFNALFVRPHIRGAIGEYQTQLIQRVKDDIEALHNKFKVQYASSTACKMSKVRDLPPVSGSIIWVRQILRQLNAYMKRVEDVLGKDWAQHIEGQKLKADGESFKLKLNTSELFEEWSKKVAEKSLSVAGSIFNVESTRTVVTVRDREPQKITVLKLKVNFLPDVITLAKEVRNMRALGFRTPLSIVNKAHSANQLYPFAISLIESVRTYESTCSKIEEHKMQNISLLTAGLRKDVQLCIHEGVQITWESYRLDQYVQKLAELVFSFQEKVDDLVIVIKEIDFNVKALETCSYNKQTFEEILIRIQEAVDNMSLHQFSNLAQWVSNLDSLVEQRLIVRLEAGLLEWIKVLKGXXXXXXXXXXXXXXXVNSMAKHRLGGKPQIKKLIHELRITNQQMHLYPSIEVATQDILYQMSSWQNIILNLSRIVHSRYQVGLETESDNQKTYKKLLSSLPNSGESLENAYAAVHNILRDANEYVKTWTNYQSLWDLQGDQLFSLIADDNTVWMNVLEEIKSMRKHFDVAETQKEFGPLVIAFGKVQSKVSMKYDNWHKEVLTKFGQNMGKMMTTLYNEVQRARNELEQQSIDSGGTNESVNFITYTQNIKRKMNTWEKQAEACRAGQNILCRDRFQFPNDWLDSENIQGEWSAFKEIMRRKQETISSQVASLQMKITEEDKIVESKTTEVLGNWEKDKPIAGDLTPEEAVNIIQILEGKFNRLKEERENVQKAKEALELTEIGVKPISEEKVTNALSELHDLKNVWNELKSIWEKIRDMKETPWLSVQPRKLRQDIENLTAQLKELPNSFKQYASFEHVRTLLKMYMKVNASIVELKSEAIKERHWRMLMRKLNVSWSLNELQLGKVWDIDLVKNEEIIREVLAIAQGEKALEEYLRQITEVWKNYVLELTNYQSKSKIIKGWDDLFNKVKEHINNVTSMKASPYFKQFEEEATAWEDRLNKINALFDVWIDVQRRWIYLDGIFAGSADIKVLLPVESQRFQSVSTEFLGLMKKVQKSPLVTDVLNIANVQRQLERLADLLGKIQKSLGEYLERQRSSFPRFYFVGDEDLLEIIGNSXXXXXXXXXXXXMFAGVHSIILSEDEKVILGMMSKEGEELRFISPVSIIEHPRINDWLTAMEKEMRVSLAKYLNVAVKEISGWRTESNIDKDKFMVWLDKYQAQIVVLAAQITWSEAVEASLASGVSLESTMTVVHSTLNMLADTVLYEQPPVRRRKLEHLIIEYVHQRDVLRALHNDGVSSNKNFDWMSQMRFYFDPKQTDPLHQLSIHVANAKFHYGFEYLGVCDRLVQTPLTDRCYLTMTQALEARLGGSPFGPAGTGKTESVKSLGNQLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLSAVSQQIQGIQEALRELMVSKKDSINVELLGKQVHVNPDMAIFITMNPGYAGRSNLPDNLKKLFRSLAMTQPDRQLIAQVMLYSQGFRTAEVLAGKVVPFFKLCDEQLSPQSHYDFGLRALKSVLVSAGNVKRDRIKQEKEKIVARGEEINETAIAEQLPEQEILIQSVMETMVPKLIADDIPLLYSLLTDVFPGVEYRQAEMKRLREELRKVSENKFLVYSDEPNTAGYLWVEKVLQLYQITTIHHGLMMVGPSGSGKTMACRVLLQALENIDGIEGVAHIIDPKSISKDSLYGYMDPNTREWTDGLFTHILRRIIDSVRGESNKRQWIVFDGDVDPEWVENLNSVLDDNKLLTLPNGERLAIPPNVRIMFEVQDLKYATLATVSRCGMVWFSEEVLTTGMILTHFLNELKKVQVMEGEEDFSVNQGD----TGADADSKISSSPIIQLQTQVSSILAPFFTEDGLIAKCLDYSTT-LEHIMDFTRLRALTSLFSMIKQSIRNMIEYNQSHSDFPLNNEQIENYVAKSLISSVVWSMSGDSKLKVREQLSQYIKNISTVDLPTVGGIKNIIDFEVNIQGTWVAWSNKVPQIEVETHKITATDVVVPTMDTVRHEALLYTWLAEHRPVLLCGPPGSGKTMTLFSALRCLPDMEVVGLNFSSATTPELMLKTFDQYCEYRKTPNGIVLAPQQLNKWLIFFCDEINLPDMDKYGTQRVISFLRQMVEHHGFYRITDMQWVSFERIQFVGACNPPTDPGRKPLSHRFLRHVPVVYVDYPGETSLKQIYSTFNRAMLRMLPSLRGYADTLTNAMVEFFLKTQERFTHDMQPHYIYSPREMTRWVRGIHEALKPLESLSVEGLVRIWAHEALRLFQDRLVEEDERHWTDDNINEVALKHFPNINK-EEALKRPILYSNWLSKDYSAVTQEELRDYVKARLKVFYEEELDVPLVLFNQVLDHVLRIDRVFRQPQGHLLLIGVSGAGKTTLSRFVSWINGLSVFQVKVHNKYTAEDFDEDLRNVLRRSGCKGEKITFIMDESNVMDSSFLERMNTLLANGEVPGLFEGDELTTLMTQCKEGAIREGLMIDSQEELYKWFTQQICRNLHVVFTMNPSADGLKDKASTSPALFNRCVLNWFGDWSLEAYFQVGKEFTNRLDLERTDYKVPDTLPCIAEGLLPQNPIYRDVVVNALVFVHQTMHQANVRVQKRGGRTAAITPRHYLDLIAHYMKLSAEKRADLEEQQLHLNNGLKKIEQTVDQVEVMQRSLTKKRQELENMNEAANAKLKQMVQDQQEAEQKKTTGQALKEELAKQEQFVNEKQKTVKQELDQVEPTVNEAKQAVQNIRKKDIQEIKAMKNPPNAVKMAVESICLLLGEKT-TDWQSILKVIIKDTFVTSILNFNTDDVSDNTRETMKKKYLSNPDYNFEKVNKASNACGPMVKWVLAQISYADILKRVEPLRNELTELSDAAEQNRKKSQETEDLIAQLEKSIAKYTEEYATLISQAQTIKSDLASVESKVGRSVALLGSLSSERTRWDSGSETFKAQMATINGDCLLSSAFMAYGGYFDQHMRTSLFNTWCHHLSEADILFRSDLARVEYLSNPDDRLRWQANSLPADDLCVENAIILRRYNRYPLIIDPSGQATTFLLNEYKEKKITKTSFLDDSFRKTLESALRFGTPLLVQDVESYDPILNPVLNREVRRTGGRTLITLGDQDIDLSPTFTIFLSTRDPSVEFAPDICSRVTFVNFTVTRSSLQNQCLNAVLKIERPDIDQKRSDLLKAQGEFQLKLRHLEKDLLQSLNEAQGNLLENDKIIARLETLKREAADVAKKVEETDVVMQEVESVSTEYVPLAQSCSNIYFTLEAMNQIHFLYQYSLQLMLDIFSSVLINNPELTNVKAASDRLKIITKNLFQVTYNRLARGMLHEDQITFATILARIFLKGSTPIGFLENEFQHFLRSQEATITSSDSNKQDNLGLT-LHQDQIDSVKRLKKL----KVFAKIEEKVKSTKDIKNWTLTVTPESNVPELWVDDNNYNDEKLSKIAKGMYNLLIIQAIRPDRLLASTQKFIASVLGDTFTESVRGTLDLASIVEVEVTACVPILLCAVQGYDPSGRVEDLASEQGKQLTGIAIGSAEGFSQAEKAINSAAKTGKWVMLKNVHLATSWLVSLEKKIHSLQAHPNFRLFLTMEITPKLPVNLLRAGRVLVFEPPPGIKANLLRTLSSINNQRMSKEPVERSRLYFLLAWLNAIVQERLRYVPLGYSKKYEFGESDFKCALDTIDTWVDGAAMGRTNLPPEKIPWVALQTLLGSCIYGGKIDNAFDQRLLNSFLGYLFTEKCFDHNFALVSDADDGSNIAFPESTKHTDILQWVHKLPDLQTPSWLGLPNSAEKVLLTNLGQSLIGNILKMQQSLEDDEELVVGQSKTKRTIEVGDGRPAWMRQLYQSTQTWLQILPKSVTPLQRTIENIKDPMYRCFEREVNSGCNLLASVRKDLEDVAEVCKGAKKPTNHHRSMMADLAKGIIPKMWIRYAIPPGLTVIQWIQDFADRIKQLLHISDTAAKSGVIALRSIQVWLGGLFMAEAYITATRQSVAQNNKWALEELFLDVELGEGKVDSNTCV-ITGLRLMGSEIVDPRTLKLSTLIYKDIDICRLKWIRVEKSQQLEGSSAKDKVCLPIYLNAARSTVLFTLYFSTTDSSYDFYKRGVAI 14048 F +++ Q +F+K + VIEA+K I++Q+ G +E +H L+ L PY DK+ P+V+K E E LLHLQQNI+IPEI L + ++ I++ +N+ A++ D D ED FLN LQ+G NRW+KEI+KVT+L RDPS+GT+LQE++FWLNLE +L KI +KR+ EV LTL LK KRFHAT FD+D L V+DYN LMK+FP+++L+SA+ + K+ A+ IF HL+K+R+TKYP+ R ++L+EA+SRDL +QL+KV+S+ +LM P EF +I + CQ +FS W+DEYDK LLRDI KKKR++ +K +WK+ A HK+L+TRL I +FR QHEQ R VI RVL+PV ++Q+ + +G+KS P+ ++V+ AYE +K +D LD ++ W+ A KRYE++I VE+ I + L+ L S+N+NEMF FSR+NALF+RP IRGAI EYQT+LI RVK+DI L +F + K+ + LPP S I+W+R RQL YMKRVEDVLGK W H++G++LKADG++FK+KLNT +F+EW + V ++ ++ I V+ R V R + L+LK+N+ D L KEV +++++GFR PL IVN AH ANQ+ P A SLIE+ RT+ S + + +Q + L A +KD+Q + EG + W+SY++DQY KLAE V ++QE+ ++L+ V++ ++ ++ L++C Y+K+T E +L IQ+ VD +SL +SNLAQWV+ LD +E L R+E + W V +E + R P +K ++ +L +T Q +++ PS + IL Q+ W ++ RI R+Q+ + E + + TY +L+ +P LE AY V+ I+ D EY+ W +YQSLW LQ +QLF ++ + WM L EI+ R FD +T+K P+ + +GK Q K+ KYD WHKE+L KFG +G M +N V + RN LE QS+D G T++++ I++ Q++K++ + + + R+ Q +L + R+QFP WL SEN++GEWSAF EI+ + +I +Q+ +LQ K +ED++VE +T E L W K KP+ G P+EA+N+I E K N+L EER ++KA+ AL+L++ P +K+T A EL +K+VW L+ ++ I + KE WLSVQPRK+RQ ++ L QLK+LP + Y S+EHV+ +L Y K+N + ELKSEA+KERHW +M+++ V+W+L++L LG+VWD D++++E I+++L +AQGE ALEE+LR++ E W+NY +EL NYQ+K+++IKGWDDLFNK+KEH N++++MK SPY+KQFEE A +W+++LNKINA+FDVWIDVQRRW+YL+G+F+GSA+I LLP ES RF +++T+ L LMKKV SP + DV+N+ QR LERLAD+L KIQK+LGEYLER+RSSFPRFYFVGDEDLLEI+GNSKD+ ++QKH KKMFAG+ +I ++E+++ I S+EGE++ + VS + RINDWL A+E EM+ +LA+ L ++ S ++ + D ++ WLDK+ AQ++ L A+I W + +E +LA G E+ V TL +LAD+VL EQPP+RR+K+E LI E VH+RD R L + + + +F W+ MRFYFDPKQ DP+ + +AN++F YGFEYLG+ +RLV+TPLTDRCYLTMTQAL +RLGGSPFGPAGTGKTESVK+LG+QLGRFVLVFNCDETFDFQAMGRI VGLCQVGAWGCFDEFNRLEERMLSAVSQQIQ IQEA+R ++V+L+GK+++VN ++ IFITMNPGY+GRSNLPDNLK+LFRSLAMTQPDRQLIAQVML+SQGFRTAE LA K+VP F LC EQLS Q HYDFGLRALK VLVSAGN+KRD++ + +A E + EQ++LIQSV ET+VPKL+ +DI LL+SLL+DVFPG+ Y +M+ LR++L V + L+YSD G +W++KVLQLYQIT ++HGLM+VG SGSGKTMA +VLL+ALE + +EGVAH+ID K++SKDSLYG MDPNTREWTDGLFT ++R+IID+VRGE+++RQWI+FDGDVDPEWVENLNSVLDDNKLLTLPNGERL+IPPNVRI+FEV DLKYATLATVSRCGMVWFSEEV+T+ M+ +L+ +++V + + G DA S I++Q + L F+ DG++ L Y+ + LEHIM T R L+S FSM+ SIR ++ +++ D + +QI+++V +S+++++VW+ SGD K K RE +S +I+ +T+ LP +ID+EV + G W W +KVP +E+E+H++ A D+VVPT+DTVRHE LL WLAEH+P++LCGPPGSGKTMTL +ALR +MEVV +NFSS+TTPEL+L+TFD YCEYR+TPNG+VLAP QL++WL+ FCDEINLP DKYGTQRVISFLRQ+VE +GFYR +D WVS ERIQFVGACNPPTDPGR P++ RFLRHVP+VYVDYPG+TSL+QIY TFNRAML+M P++RG AD LTNAMV+ +L +QE FT D QPHY+YSPRE+TRWVRGI EA+ PLESLS E LVR+WAHEA+RLFQDRLV E+ER WTD ++ A ++F N + +EALKRP+LYS WLS++Y VT+EEL+DYV ARLK FYEEELDV LVLF+Q+LDHVLRIDR++RQ QGHLLLIG +GAGKTTLSRFV+W+NGLSVFQ+KVH+KYTA DFDED+R VLRR+GC+ EK+ FIMDESN++D+ FLER+NTLLANGEVPGLFEGDE TTLMTQ KEGA R+GL++DS +ELYKWFTQQ+ RNLHVVFTMNPS GL+++ASTSPALFNRCVLNWFGDWS A +QVG E T +DL+RTDY+ L E L+P P YRD VVN L VH+T+ + N K+G R A TPRH+LD I +M L EKR+DLEE+++HLN GL KI +T +QV+ +Q+SL K EL+ EAAN KLK+M+ DQQ+AE++K + L++ELA+Q + + EK+ V+ +L QVEP V EA+ AVQ I+K + E+K+M +PP VK+ +E+IC+LLGE TDW++I +V++KD F+T IL F+T+ ++ + M +KY+ NPD+ F+KVN+AS ACGPMVKW AQ+ Y+ +L +VEPLRNEL L A + ++ + + I +LE+SI KY EEYA LI QA+ IK DL SV+ KV RS LL SL SER RW SGS F QM ++ GD LLSSAF+AY GY+DQ +R +F+ W +H+ A + FR DLAR+EYLS DDRL+WQ NSLP DDLC ENAI+L R+NRYPLIIDPSGQA +++ ++ K I KTSFLD+SFRK LESALRFG LLVQDVE+YDPILNPVLNREV+R GGR LIT+GDQDIDLSP+F IF+ TRD +VEF+PDICSRVTFVNFTVT SSL +QCLN VL+ ERPD+D+KR+DLLK QGEF ++LRHLEK LL +LNE++G +L+++ +I LE LK EAA+VA+K ETD VM EV++VS +Y L+ +CS+IY TL+ +N+IHFLY YSL +++IF+ VL PEL++ + RL+IIT +LFQ + R++RGMLH D++ A +L RI ++ + E F L + + +++ GL L + S+ + +K+ VFA ++ ++ + +W PESNVP +W D D KLS + M +L+++ A+RPDRL+AS + +++ D F + + +D+ SIV+ EV+ P+LLC+ GYD SG++EDLA E +QLT IAIGSAEGF+QA+ A+ +A K+G+WV+LKNVHLA SWL LEK++HS++ H FRLFLT EI PKLP ++LRA RV+VFEP G+KANLLR+LSSI QR++K P ERSRLY L+ WL+A+VQERLRY PLG+S YEF ++D + A DT+D VD A GR N+ PE++PW L+TLL CIYGGKIDN FDQ LL+ L LFT K F+ + L+ D ++ P +K ++ WV +L + Q P+WLGLPN+AEKVLLT G+S++ N+LK+ DEEL + + +P WM QL + + WLQ+LPK + ++RT+ENIKDP++R FEREVN G LL +R+DL +++ VC+ KK N R++ A L KG +P W RY +P +TV+ W+ D +R+KQL+ I G L+ WLGG F EAYITATRQ VAQ N W+LE+L L + + G+ DS I+G+ + G++ V L+L L+ + DI W D LP+YL R ++ L F + ++ FY+RGVA+ Sbjct: 104 FMTDRGQAMMFVKQSNVIEAEKKIATQVSAFPLNGGSAWEQLHFLMSRLLNPY-CKSFIGQSGRGERDGDKLAPTVQKCFTEAEAALLHLQQNIDIPEINLVVNQHILDAIEQAGKENRRAKIEDLGDLVEDANFLNALQSGCNRWVKEIRKVTQLERDPSSGTSLQEMTFWLNLERALLKISQKRDGEEVTLTLEALKCGKRFHATVGFDSDNGLKQKLAVVQDYNTLMKEFPLSELVSATDVPKLMHAVVGIFLHLRKLRSTKYPLQRALRLVEAISRDLNSQLLKVLSSYNLMRTPIAEFNEIMSQCQALFSKWDDEYDKFIALLRDINKKKRDDPSKLSWKVTAVHKRLETRLMQILQFRKQHEQFRTVIERVLRPVGN------GSREREQLMIDSSEGEKS----PD-------EQVDIAYEFLKNVDFLDV---DSPAWENAFKRYEDQIGVVETAITTRLKSQLESSRNSNEMFSIFSRYNALFIRPRIRGAIYEYQTRLINRVKEDINELQARF-TKARGEQGVKIMQTVGLPPFSAKIMWIRNYERQLQRYMKRVEDVLGKQWENHVDGRQLKADGDNFKVKLNTQPMFDEWVESVQSQNWTLPNKILTVD--RVQVDGRMQ-------LQLKINYHSDSSVLYKEVSHLKSMGFRVPLKIVNWAHQANQMRPSATSLIEAARTFASVNAALA--SVQGVDSLLASYKKDIQNQLIEGATLGWDSYKVDQYQLKLAETVNTYQERCEELLNVVRIVNADLNVLKSCRYDKETIENLLTSIQKGVDQLSLGNYSNLAQWVNTLDRQIETILARRVEDAIRVWTLVFSQSEEVEEL-------------RERQVVLPTVKNVVVDLCMTAQTLYISPSTRETREKILEQLYEWHSVCTAQMRISGKRFQMVMNEEIEPE-TYHNILNVMPEGQACLEKAYDCVNGIMSDLEEYLSEWLSYQSLWVLQAEQLFEMLGTSLSKWMKTLMEIRKGRLVFDTQDTRKVIFPVSVEYGKAQQKILFKYDYWHKEMLVKFGAVVGDEMQKFFNSVSKWRNVLETQSVDGGSTSDTIGLISFVQSLKKQTKSGQDAVDLYRSSQRLLNQQRYQFPAQWLYSENVEGEWSAFTEILSLRDASIQTQMMNLQTKFAQEDELVEKRTVETLTEWNKSKPVEGAQRPQEALNVITAFEAKLNKLTEERNKMRKARVALDLSDSAHAPSEGDKLTVATEELAAMKDVWKALQPVYTGIDEAKEKTWLSVQPRKIRQSLDELMNQLKQLPVKCRTYKSYEHVKQMLHTYGKMNMLVAELKSEALKERHWHQMMKEMRVNWNLSDLTLGQVWDADILRHEHTIKKILLVAQGEMALEEFLREMREYWQNYEVELVNYQNKTRLIKGWDDLFNKLKEHQNSLSAMKLSPYYKQFEESAQSWDEKLNKINAMFDVWIDVQRRWVYLEGLFSGSAEISTLLPFESSRFATITTDVLALMKKVAASPRILDVVNMQGAQRLLERLADMLAKIQKALGEYLERERSSFPRFYFVGDEDLLEIMGNSKDITRIQKHLKKMFAGITAIDINEEDRSITAFHSREGEKVDLVKIVS-TKDVRINDWLQALEAEMKHTLARQLAASLTHFSKMNIQT-MTTDDYVEWLDKFPAQVITLTAEIWWCDEMEKTLADGKGAENVEQAVVKTLELLADSVLKEQPPIRRKKMEALITELVHKRDTCRKLVSMKIRAANDFGWLQCMRFYFDPKQVDPVRCCVVKMANSQFFYGFEYLGIQERLVRTPLTDRCYLTMTQALHSRLGGSPFGPAGTGKTESVKALGHQLGRFVLVFNCDETFDFQAMGRILVGLCQVGAWGCFDEFNRLEERMLSAVSQQIQTIQEAVR-----AGGDMSVDLVGKRLNVNSNIGIFITMNPGYSGRSNLPDNLKQLFRSLAMTQPDRQLIAQVMLFSQGFRTAETLANKIVPLFILCKEQLSDQCHYDFGLRALKYVLVSAGNIKRDKLDKMG------------SAALEDVAEQQMLIQSVCETLVPKLVNEDIALLFSLLSDVFPGIHYTANQMRELRQQLSTVCDEHLLIYSDVQGEMGSMWLDKVLQLYQITNLNHGLMLVGSSGSGKTMAWKVLLKALERWENVEGVAHVIDAKAMSKDSLYGVMDPNTREWTDGLFTSVIRKIIDNVRGEADRRQWIIFDGDVDPEWVENLNSVLDDNKLLTLPNGERLSIPPNVRIIFEVADLKYATLATVSRCGMVWFSEEVVTSEMLFERYLSIIRRVPLDSDSAISFSSSSAPVNLIGEDAKPTRS----IEIQRTAALALQTHFSPDGIVPGSLKYAVSELEHIMPPTPQRLLSSFFSMMSYSIRKIVSHDEGLIDDSVEIDQIQSFVLRSMLTNLVWAFSGDGKWKSREMMSDFIRQATTISLPP-NQQACLIDYEVQLSGDWQPWLSKVPTMEIESHRVAAADLVVPTIDTVRHEMLLAAWLAEHKPLVLCGPPGSGKTMTLLAALRSQQEMEVVNVNFSSSTTPELLLRTFDHYCEYRRTPNGVVLAPVQLSQWLVIFCDEINLPAPDKYGTQRVISFLRQLVELNGFYRTSDHSWVSLERIQFVGACNPPTDPGRHPMTSRFLRHVPIVYVDYPGQTSLQQIYGTFNRAMLKMTPAVRGLADQLTNAMVDVYLASQEHFTQDDQPHYVYSPRELTRWVRGISEAITPLESLSAEQLVRLWAHEAIRLFQDRLVTEEEREWTDKLVDTTAERYFGNACRLDEALKRPLLYSCWLSRNYVPVTREELQDYVSARLKGFYEEELDVKLVLFDQMLDHVLRIDRIYRQSQGHLLLIGTAGAGKTTLSRFVAWLNGLSVFQLKVHSKYTAADFDEDMRTVLRRAGCRNEKLCFIMDESNMLDTGFLERLNTLLANGEVPGLFEGDEHTTLMTQIKEGAQRQGLILDSHDELYKWFTQQVMRNLHVVFTMNPSGSGLRERASTSPALFNRCVLNWFGDWSENALYQVGSELTRTMDLDRTDYEGSVRLTPSCE-LVPSQPTYRDAVVNTLCLVHKTVQKFNEMETKKGHRVMACTPRHFLDFIKQFMSLFHEKRSDLEEEKIHLNIGLNKISETEEQVKELQKSLKLKSNELQEKKEAANLKLKEMLGDQQKAEEEKKFSEQLQKELAEQLKQMAEKKTFVENDLAQVEPAVAEAQTAVQGIKKSQLVEVKSMSSPPVTVKLTLEAICILLGENVGTDWKAIRQVMMKDDFMTRILQFDTELLTPEILKQM-EKYIQNPDWEFDKVNRASVACGPMVKWARAQLLYSTMLHKVEPLRNELKRLEQEAAKKTQEGKVVDVRITELEESIGKYKEEYAQLIGQAENIKQDLLSVQEKVNRSTELLSSLRSERDRWSSGSAGFSQQMDSLVGDALLSSAFLAYAGYYDQMLRDEIFHKWFNHVVNAGLHFRHDLARIEYLSTVDDRLQWQLNSLPVDDLCTENAIMLHRFNRYPLIIDPSGQAVEYIMKQFAGKNIQKTSFLDESFRKNLESALRFGNSLLVQDVEAYDPILNPVLNREVKRAGGRVLITIGDQDIDLSPSFQIFMITRDSTVEFSPDICSRVTFVNFTVTSSSLASQCLNQVLRSERPDVDKKRNDLLKLQGEFAVRLRHLEKALLAALNESKGKILDDNSVIETLEKLKNEAAEVAQKSAETDKVMAEVDAVSAQYQRLSTACSHIYHTLQQLNEIHFLYHYSLDFLVEIFTHVL-KTPELSSTTDYAKRLRIITTSLFQTVFRRVSRGMLHTDKVLLALLLMRIHIRSNPSAPAYEQHFDLLLGRSDFVAKNDEADSTIPGGLDFLTVENKKSIAKARKVVGFENVFAHLQH---NSAAVTSWLTNDNPESNVPVVWDD----ADGKLSPLCIAMNSLIVVHALRPDRLMASAHRVVSTAFDDHFMQQDK-VVDILSIVDNEVSPSEPVLLCSATGYDASGKIEDLAVETNRQLTSIAIGSAEGFNQADSALGTATKSGRWVLLKNVHLAPSWLAQLEKRLHSMKPHAQFRLFLTAEIHPKLPSSILRASRVVVFEPATGLKANLLRSLSSIPPQRLTKAPTERSRLYLLVCWLHALVQERLRYTPLGWSTAYEFSDADLRVACDTLDAAVDAVAQGRPNVEPERLPWTTLRTLLSQCIYGGKIDNQFDQVLLDCVLENLFTAKSFEQDHVLIPKYDGDDSLFTPNMSKKDQMIGWVEELKNEQLPAWLGLPNNAEKVLLTKRGESMLRNMLKVT-----DEELAFNEDGKEEV------KPQWMAQLGELAKQWLQLLPKEIVKMRRTVENIKDPLFRFFEREVNLGSQLLKDIRRDLNEISAVCRAEKKQNNETRALAASLQKGEVPTGWKRYTVPREVTVMDWMTDLNERLKQLIRI------GGADNLKRETFWLGGTFSPEAYITATRQQVAQANTWSLEQLNLHIHI--GRTDSTDVFRISGIDIRGAKSVGGNKLELCELVKSECDIVEFSW----------KQDVADGTRLPLYLYGDRRQLISPLAFHLSSATV-FYQRGVAL 4562
BLAST of Cytoplasmic dynein 1 heavy chain 1 vs. Ensembl Celegans
Match: dhc-1 (Dynein heavy chain, cytoplasmic [Source:UniProtKB/Swiss-Prot;Acc:Q19020]) HSP 1 Score: 4145.89 bits (10751), Expect = 0.000e+0 Identity = 2015/3696 (54.52%), Postives = 2681/3696 (72.54%), Query Frame = 3 Query: 3000 ITNQQMHLYPSIEVATQDILYQMSSWQNIILNLSRIVHSRYQVGLETESDNQKTYKKLLSSLPNSGESLENAYAAVHNILRDANEYVKTWTNYQSLWDLQGDQLFSLIADDNTVWMNVLEEIKSMRKHFDVAETQKEFGPLVIAFGKVQSKVSMKYDNWHKEVLTKFGQNMGKMMTTLYNEVQRARNELEQQSIDSGGTNESVNFITYTQNIKRKMNTWEKQAEACRAGQNILCRDRFQFPNDWLDSENIQGEWSAFKEIMRRKQETISSQVASLQMKITEEDKIVESKTTEVLGNWEKDKPIAGDLTPEEAVNIIQILEGKFNRLKEERENVQKAKEALELTEIGVKPISEEKVTNALSELHDLKNVWNELKSIWEKIRDMKETPWLSVQPRKLRQDIENLTAQLKELPNSFKQYASFEHVRTLLKMYMKVNASIVELKSEAIKERHWRMLMRKLNVSWSLNELQLGKVWDIDLVKNEEIIREVLAIAQGEKALEEYLRQITEVWKNYVLELTNYQSKSKIIKGWDDLFNKVKEHINNVTSMKASPYFKQFEEEATAWEDRLNKINALFDVWIDVQRRWIYLDGIFAGSADIKVLLPVESQRFQSVSTEFLGLMKKVQKSPLVTDVLNIANVQRQLERLADLLGKIQKSLGEYLERQRSSFPRFYFVGDEDLLEIIGNSXXXXXXXXXXXXMFAGVHSIILSEDEKVILGMMSKEGEELRFISPVSIIEHPRINDWLTAMEKEMRVSLAKYLNVAVKEISGWRTESNIDKDKFMVWLDKYQAQIVVLAAQITWSEAVEASLASGVSLESTMTVVHSTLNMLADTVLYEQPPVRRRKLEHLIIEYVHQRDVLRALHNDGVSSNKNFDWMSQMRFYFDPKQTDPLHQLSIHVANAKFHYGFEYLGVCDRLVQTPLTDRCYLTMTQALEARLGGSPFGPAGTGKTESVKSLGNQLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLSAVSQQIQGIQEALRELMVSKKDSINVELLGKQVHVNPDMAIFITMNPGYAGRSNLPDNLKKLFRSLAMTQPDRQLIAQVMLYSQGFRTAEVLAGKVVPFFKLCDEQLSPQSHYDFGLRALKSVLVSAGNVKRDRIKQEKEKIVARGEEINETAIAEQLPEQEILIQSVMETMVPKLIADDIPLLYSLLTDVFPGVEYRQAEMKRLREELRKVSENKFLVYSDEPNTAGYLWVEKVLQLYQITTIHHGLMMVGPSGSGKTMACRVLLQALENIDGIEGVAHIIDPKSISKDSLYGYMDPNTREWTDGLFTHILRRIIDSVRGESNKRQWIVFDGDVDPEWVENLNSVLDDNKLLTLPNGERLAIPPNVRIMFEVQDLKYATLATVSRCGMVWFSEEVLTTGMILTHFLNELKKVQVMEGEEDFSVNQGD----TGADADSKISSSPIIQLQTQVSSILAPFFTEDGLIAKCLDYSTT-LEHIMDFTRLRALTSLFSMIKQSIRNMIEYNQSHSDFPLNNEQIENYVAKSLISSVVWSMSGDSKLKVREQLSQYIKNISTVDLPTVGGIKNIIDFEVNIQGTWVAWSNKVPQIEVETHKITATDVVVPTMDTVRHEALLYTWLAEHRPVLLCGPPGSGKTMTLFSALRCLPDMEVVGLNFSSATTPELMLKTFDQYCEYRKTPNGIVLAPQQLNKWLIFFCDEINLPDMDKYGTQRVISFLRQMVEHHGFYRITDMQWVSFERIQFVGACNPPTDPGRKPLSHRFLRHVPVVYVDYPGETSLKQIYSTFNRAMLRMLPSLRGYADTLTNAMVEFFLKTQERFTHDMQPHYIYSPREMTRWVRGIHEALKPLESLSVEGLVRIWAHEALRLFQDRLVEEDERHWTDDNINEVALKHFPNINK-EEALKRPILYSNWLSKDYSAVTQEELRDYVKARLKVFYEEELDVPLVLFNQVLDHVLRIDRVFRQPQGHLLLIGVSGAGKTTLSRFVSWINGLSVFQVKVHNKYTAEDFDEDLRNVLRRSGCKGEKITFIMDESNVMDSSFLERMNTLLANGEVPGLFEGDELTTLMTQCKEGAIREGLMIDSQEELYKWFTQQICRNLHVVFTMNPSADGLKDKASTSPALFNRCVLNWFGDWSLEAYFQVGKEFTNRLDLERTDYKVPDTLPCIAEGLLPQNPIYRDVVVNALVFVHQTMHQANVRVQKRGGRTAAITPRHYLDLIAHYMKLSAEKRADLEEQQLHLNNGLKKIEQTVDQVEVMQRSLTKKRQELENMNEAANAKLKQMVQDQQEAEQKKTTGQALKEELAKQEQFVNEKQKTVKQELDQVEPTVNEAKQAVQNIRKKDIQEIKAMKNPPNAVKMAVESICLLLGEKT-TDWQSILKVIIKDTFVTSILNFNTDDVSDNTRETMKKKYLSNPDYNFEKVNKASNACGPMVKWVLAQISYADILKRVEPLRNELTELSDAAEQNRKKSQETEDLIAQLEKSIAKYTEEYATLISQAQTIKSDLASVESKVGRSVALLGSLSSERTRWDSGSETFKAQMATINGDCLLSSAFMAYGGYFDQHMRTSLFNTWCHHLSEADILFRSDLARVEYLSNPDDRLRWQANSLPADDLCVENAIILRRYNRYPLIIDPSGQATTFLLNEYKEKKITKTSFLDDSFRKTLESALRFGTPLLVQDVESYDPILNPVLNREVRRTGGRTLITLGDQDIDLSPTFTIFLSTRDPSVEFAPDICSRVTFVNFTVTRSSLQNQCLNAVLKIERPDIDQKRSDLLKAQGEFQLKLRHLEKDLLQSLNEAQGNLLENDKIIARLETLKREAADVAKKVEETDVVMQEVESVSTEYVPLAQSCSNIYFTLEAMNQIHFLYQYSLQLMLDIFSSVLINNPELTNVKAASDRLKIITKNLFQVTYNRLARGMLHEDQITFATILARIFLKGSTPIGFLENEFQHFLRSQEATITSSDSNKQDNLGLT-LHQDQIDSVKRLKKL----KVFAKIEEKVKSTKDIKNWTLTVTPESNVPELWVDDNNYNDEKLSKIAKGMYNLLIIQAIRPDRLLASTQKFIASVLGDTFTESVRGTLDLASIVEVEVTACVPILLCAVQGYDPSGRVEDLASEQGKQLTGIAIGSAEGFSQAEKAINSAAKTGKWVMLKNVHLATSWLVSLEKKIHSLQAHPNFRLFLTMEITPKLPVNLLRAGRVLVFEPPPGIKANLLRTLSSINNQRMSKEPVERSRLYFLLAWLNAIVQERLRYVPLGYSKKYEFGESDFKCALDTIDTWVDGAAMGRTNLPPEKIPWVALQTLLGSCIYGGKIDNAFDQRLLNSFLGYLFTEKCFDHNFALVSDADDGSNIAFPESTKHTDILQWVHKLPDLQTPSWLGLPNSAEKVLLTNLGQSLIGNILKMQQSLEDDEELVVGQSKTKRTIEVGDGRPAWMRQLYQSTQTWLQILPKSVTPLQRTIENIKDPMYRCFEREVNSGCNLLASVRKDLEDVAEVCKGAKKPTNHHRSMMADLAKGIIPKMWIRYAIPPGLTVIQWIQDFADRIKQLLHISDTAAKSGVIALRSIQVWLGGLFMAEAYITATRQSVAQNNKWALEELFLDVELGEGKVDSNTCV-ITGLRLMGSEIVDPRTLKLSTLIYKDIDICRLKWIRVEKSQQLEGSSAKDKVCLPIYLNAARSTVLFTLYFSTTDSSYDFYKRGVAI 14048 +T Q +++ PS + IL Q+ W ++ RI R+Q+ + E + + TY +L+ +P LE AY V+ I+ D EY+ W +YQSLW LQ +QLF ++ + WM L EI+ R FD +T+K P+ + +GK Q K+ KYD WHKE+L KFG +G M +N V + RN LE QS+D G T++++ I++ Q++K++ + + + R+ Q +L + R+QFP WL SEN++GEWSAF EI+ + +I +Q+ +LQ K +ED++VE +T E L W K KP+ G P+EA+N+I E K N+L EER ++KA+ AL+L++ P +K+T A EL +K+VW L+ ++ I + KE WLSVQPRK+RQ ++ L QLK+LP + Y S+EHV+ +L Y K+N + ELKSEA+KERHW +M+++ V+W+L++L LG+VWD D++++E I+++L +AQGE ALEE+LR++ E W+NY +EL NYQ+K+++IKGWDDLFNK+KEH N++++MK SPY+KQFEE A +W+++LNKINA+FDVWIDVQRRW+YL+G+F+GSA+I LLP ES RF +++T+ L LMKKV SP + DV+N+ QR LERLAD+L KIQK+LGEYLER+RSSFPRFYFVGDEDLLEI+GNSKD+ ++QKH KKMFAG+ +I ++E+++ I S+EGE++ + VS + RINDWL A+E EM+ +LA+ L ++ S ++ + D ++ WLDK+ AQ++ L A+I W + +E +LA G E+ V TL +LAD+VL EQPP+RR+K+E LI E VH+RD R L + + + +F W+ MRFYFDPKQ DP+ + +AN++F YGFEYLG+ +RLV+TPLTDRCYLTMTQAL +RLGGSPFGPAGTGKTESVK+LG+QLGRFVLVFNCDETFDFQAMGRI VGLCQVGAWGCFDEFNRLEERMLSAVSQQIQ IQEA+R ++V+L+GK+++VN ++ IFITMNPGY+GRSNLPDNLK+LFRSLAMTQPDRQLIAQVML+SQGFRTAE LA K+VP F LC EQLS Q HYDFGLRALK VLVSAGN+KRD++ + +A E + EQ++LIQSV ET+VPKL+ +DI LL+SLL+DVFPG+ Y +M+ LR++L V + L+YSD G +W++KVLQLYQIT ++HGLM+VG SGSGKTMA +VLL+ALE + +EGVAH+ID K++SKDSLYG MDPNTREWTDGLFT ++R+IID+VRGE+++RQWI+FDGDVDPEWVENLNSVLDDNKLLTLPNGERL+IPPNVRI+FEV DLKYATLATVSRCGMVWFSEEV+T+ M+ +L+ +++V + + G DA S I++Q + L F+ DG++ L Y+ + LEHIM T R L+S FSM+ SIR ++ +++ D + +QI+++V +S+++++VW+ SGD K K RE +S +I+ +T+ LP +ID+EV + G W W +KVP +E+E+H++ A D+VVPT+DTVRHE LL WLAEH+P++LCGPPGSGKTMTL +ALR +MEVV +NFSS+TTPEL+L+TFD YCEYR+TPNG+VLAP QL++WL+ FCDEINLP DKYGTQRVISFLRQ+VE +GFYR +D WVS ERIQFVGACNPPTDPGR P++ RFLRHVP+VYVDYPG+TSL+QIY TFNRAML+M P++RG AD LTNAMV+ +L +QE FT D QPHY+YSPRE+TRWVRGI EA+ PLESLS E LVR+WAHEA+RLFQDRLV E+ER WTD ++ A ++F N + +EALKRP+LYS WLS++Y VT+EEL+DYV ARLK FYEEELDV LVLF+Q+LDHVLRIDR++RQ QGHLLLIG +GAGKTTLSRFV+W+NGLSVFQ+KVH+KYTA DFDED+R VLRR+GC+ EK+ FIMDESN++D+ FLER+NTLLANGEVPGLFEGDE TTLMTQ KEGA R+GL++DS +ELYKWFTQQ+ RNLHVVFTMNPS GL+++ASTSPALFNRCVLNWFGDWS A +QVG E T +DL+RTDY+ L E L+P P YRD VVN L VH+T+ + N K+G R A TPRH+LD I +M L EKR+DLEE+++HLN GL KI +T +QV+ +Q+SL K EL+ EAAN KLK+M+ DQQ+AE++K + L++ELA+Q + + EK+ V+ +L QVEP V EA+ AVQ I+K + E+K+M +PP VK+ +E+IC+LLGE TDW++I +V++KD F+T IL F+T+ ++ + M +KY+ NPD+ F+KVN+AS ACGPMVKW AQ+ Y+ +L +VEPLRNEL L A + ++ + + I +LE+SI KY EEYA LI QA+ IK DL SV+ KV RS LL SL SER RW SGS F QM ++ GD LLSSAF+AY GY+DQ +R +F+ W +H+ A + FR DLAR+EYLS DDRL+WQ NSLP DDLC ENAI+L R+NRYPLIIDPSGQA +++ ++ K I KTSFLD+SFRK LESALRFG LLVQDVE+YDPILNPVLNREV+R GGR LIT+GDQDIDLSP+F IF+ TRD +VEF+PDICSRVTFVNFTVT SSL +QCLN VL+ ERPD+D+KR+DLLK QGEF ++LRHLEK LL +LNE++G +L+++ +I LE LK EAA+VA+K ETD VM EV++VS +Y L+ +CS+IY TL+ +N+IHFLY YSL +++IF+ VL PEL++ + RL+IIT +LFQ + R++RGMLH D++ A +L RI ++ + E F L + + +++ GL L + S+ + +K+ VFA ++ ++ + +W PESNVP +W D D KLS + M +L+++ A+RPDRL+AS + +++ D F + + +D+ SIV+ EV+ P+LLC+ GYD SG++EDLA E +QLT IAIGSAEGF+QA+ A+ +A K+G+WV+LKNVHLA SWL LEK++HS++ H FRLFLT EI PKLP ++LRA RV+VFEP G+KANLLR+LSSI QR++K P ERSRLY L+ WL+A+VQERLRY PLG+S YEF ++D + A DT+D VD A GR N+ PE++PW L+TLL CIYGGKIDN FDQ LL+ L LFT K F+ + L+ D ++ P +K ++ WV +L + Q P+WLGLPN+AEKVLLT G+S++ N+LK+ DEEL + + +P WM QL + + WLQ+LPK + ++RT+ENIKDP++R FEREVN G LL +R+DL +++ VC+ KK N R++ A L KG +P W RY +P +TV+ W+ D +R+KQL+ I G L+ WLGG F EAYITATRQ VAQ N W+LE+L L + + G+ DS I+G+ + G++ V L+L L+ + DI W D LP+YL R ++ L F + ++ FY+RGVA+ Sbjct: 1 MTAQTLYISPSTRETREKILEQLYEWHSVCTAQMRISGKRFQMVMNEEIEPE-TYHNILNVMPEGQACLEKAYDCVNGIMSDLEEYLSEWLSYQSLWVLQAEQLFEMLGTSLSKWMKTLMEIRKGRLVFDTQDTRKVIFPVSVEYGKAQQKILFKYDYWHKEMLVKFGAVVGDEMQKFFNSVSKWRNVLETQSVDGGSTSDTIGLISFVQSLKKQTKSGQDAVDLYRSSQRLLNQQRYQFPAQWLYSENVEGEWSAFTEILSLRDASIQTQMMNLQTKFAQEDELVEKRTVETLTEWNKSKPVEGAQRPQEALNVITAFEAKLNKLTEERNKMRKARVALDLSDSAHAPSEGDKLTVATEELAAMKDVWKALQPVYTGIDEAKEKTWLSVQPRKIRQSLDELMNQLKQLPVKCRTYKSYEHVKQMLHTYGKMNMLVAELKSEALKERHWHQMMKEMRVNWNLSDLTLGQVWDADILRHEHTIKKILLVAQGEMALEEFLREMREYWQNYEVELVNYQNKTRLIKGWDDLFNKLKEHQNSLSAMKLSPYYKQFEESAQSWDEKLNKINAMFDVWIDVQRRWVYLEGLFSGSAEISTLLPFESSRFATITTDVLALMKKVAASPRILDVVNMQGAQRLLERLADMLAKIQKALGEYLERERSSFPRFYFVGDEDLLEIMGNSKDITRIQKHLKKMFAGITAIDINEEDRSITAFHSREGEKVDLVKIVS-TKDVRINDWLQALEAEMKHTLARQLAASLTHFSKMNIQT-MTTDDYVEWLDKFPAQVITLTAEIWWCDEMEKTLADGKGAENVEQAVVKTLELLADSVLKEQPPIRRKKMEALITELVHKRDTCRKLVSMKIRAANDFGWLQCMRFYFDPKQVDPVRCCVVKMANSQFFYGFEYLGIQERLVRTPLTDRCYLTMTQALHSRLGGSPFGPAGTGKTESVKALGHQLGRFVLVFNCDETFDFQAMGRILVGLCQVGAWGCFDEFNRLEERMLSAVSQQIQTIQEAVR-----AGGDMSVDLVGKRLNVNSNIGIFITMNPGYSGRSNLPDNLKQLFRSLAMTQPDRQLIAQVMLFSQGFRTAETLANKIVPLFILCKEQLSDQCHYDFGLRALKYVLVSAGNIKRDKLDKMG------------SAALEDVAEQQMLIQSVCETLVPKLVNEDIALLFSLLSDVFPGIHYTANQMRELRQQLSTVCDEHLLIYSDVQGEMGSMWLDKVLQLYQITNLNHGLMLVGSSGSGKTMAWKVLLKALERWENVEGVAHVIDAKAMSKDSLYGVMDPNTREWTDGLFTSVIRKIIDNVRGEADRRQWIIFDGDVDPEWVENLNSVLDDNKLLTLPNGERLSIPPNVRIIFEVADLKYATLATVSRCGMVWFSEEVVTSEMLFERYLSIIRRVPLDSDSAISFSSSSAPVNLIGEDAKPTRS----IEIQRTAALALQTHFSPDGIVPGSLKYAVSELEHIMPPTPQRLLSSFFSMMSYSIRKIVSHDEGLIDDSVEIDQIQSFVLRSMLTNLVWAFSGDGKWKSREMMSDFIRQATTISLPP-NQQACLIDYEVQLSGDWQPWLSKVPTMEIESHRVAAADLVVPTIDTVRHEMLLAAWLAEHKPLVLCGPPGSGKTMTLLAALRSQQEMEVVNVNFSSSTTPELLLRTFDHYCEYRRTPNGVVLAPVQLSQWLVIFCDEINLPAPDKYGTQRVISFLRQLVELNGFYRTSDHSWVSLERIQFVGACNPPTDPGRHPMTSRFLRHVPIVYVDYPGQTSLQQIYGTFNRAMLKMTPAVRGLADQLTNAMVDVYLASQEHFTQDDQPHYVYSPRELTRWVRGISEAITPLESLSAEQLVRLWAHEAIRLFQDRLVTEEEREWTDKLVDTTAERYFGNACRLDEALKRPLLYSCWLSRNYVPVTREELQDYVSARLKGFYEEELDVKLVLFDQMLDHVLRIDRIYRQSQGHLLLIGTAGAGKTTLSRFVAWLNGLSVFQLKVHSKYTAADFDEDMRTVLRRAGCRNEKLCFIMDESNMLDTGFLERLNTLLANGEVPGLFEGDEHTTLMTQIKEGAQRQGLILDSHDELYKWFTQQVMRNLHVVFTMNPSGSGLRERASTSPALFNRCVLNWFGDWSENALYQVGSELTRTMDLDRTDYEGSVRLTPSCE-LVPSQPTYRDAVVNTLCLVHKTVQKFNEMETKKGHRVMACTPRHFLDFIKQFMSLFHEKRSDLEEEKIHLNIGLNKISETEEQVKELQKSLKLKSNELQEKKEAANLKLKEMLGDQQKAEEEKKFSEQLQKELAEQLKQMAEKKTFVENDLAQVEPAVAEAQTAVQGIKKSQLVEVKSMSSPPVTVKLTLEAICILLGENVGTDWKAIRQVMMKDDFMTRILQFDTELLTPEILKQM-EKYIQNPDWEFDKVNRASVACGPMVKWARAQLLYSTMLHKVEPLRNELKRLEQEAAKKTQEGKVVDVRITELEESIGKYKEEYAQLIGQAENIKQDLLSVQEKVNRSTELLSSLRSERDRWSSGSAGFSQQMDSLVGDALLSSAFLAYAGYYDQMLRDEIFHKWFNHVVNAGLHFRHDLARIEYLSTVDDRLQWQLNSLPVDDLCTENAIMLHRFNRYPLIIDPSGQAVEYIMKQFAGKNIQKTSFLDESFRKNLESALRFGNSLLVQDVEAYDPILNPVLNREVKRAGGRVLITIGDQDIDLSPSFQIFMITRDSTVEFSPDICSRVTFVNFTVTSSSLASQCLNQVLRSERPDVDKKRNDLLKLQGEFAVRLRHLEKALLAALNESKGKILDDNSVIETLEKLKNEAAEVAQKSAETDKVMAEVDAVSAQYQRLSTACSHIYHTLQQLNEIHFLYHYSLDFLVEIFTHVL-KTPELSSTTDYAKRLRIITTSLFQTVFRRVSRGMLHTDKVLLALLLMRIHIRSNPSAPAYEQHFDLLLGRSDFVAKNDEADSTIPGGLDFLTVENKKSIAKARKVVGFENVFAHLQH---NSAAVTSWLTNDNPESNVPVVWDD----ADGKLSPLCIAMNSLIVVHALRPDRLMASAHRVVSTAFDDHFMQQDK-VVDILSIVDNEVSPSEPVLLCSATGYDASGKIEDLAVETNRQLTSIAIGSAEGFNQADSALGTATKSGRWVLLKNVHLAPSWLAQLEKRLHSMKPHAQFRLFLTAEIHPKLPSSILRASRVVVFEPATGLKANLLRSLSSIPPQRLTKAPTERSRLYLLVCWLHALVQERLRYTPLGWSTAYEFSDADLRVACDTLDAAVDAVAQGRPNVEPERLPWTTLRTLLSQCIYGGKIDNQFDQVLLDCVLENLFTAKSFEQDHVLIPKYDGDDSLFTPNMSKKDQMIGWVEELKNEQLPAWLGLPNNAEKVLLTKRGESMLRNMLKVT-----DEELAFNEDGKEEV------KPQWMAQLGELAKQWLQLLPKEIVKMRRTVENIKDPLFRFFEREVNLGSQLLKDIRRDLNEISAVCRAEKKQNNETRALAASLQKGEVPTGWKRYTVPREVTVMDWMTDLNERLKQLIRI------GGADNLKRETFWLGGTFSPEAYITATRQQVAQANTWSLEQLNLHIHI--GRTDSTDVFRISGIDIRGAKSVGGNKLELCELVKSECDIVEFSW----------KQDVADGTRLPLYLYGDRRQLISPLAFHLSSATV-FYQRGVAL 3630
BLAST of Cytoplasmic dynein 1 heavy chain 1 vs. Ensembl Celegans
Match: che-3 (Cytoplasmic dynein 2 heavy chain 1 [Source:UniProtKB/Swiss-Prot;Acc:Q19542]) HSP 1 Score: 634.41 bits (1635), Expect = 0.000e+0 Identity = 394/1177 (33.47%), Postives = 646/1177 (54.89%), Query Frame = 3 Query: 3741 ENIQGEWSAFKEIMRRKQETISSQVASLQMKITEEDKIVESKTTEVLGNWEKDKP----IAGDLTPEEAVNIIQILEGK---FNRLKEERENVQKAKEALELTEIGVKPISEEKVTNALSELHDLKNVWNELKSIWEKIRDMKETPWLSVQPRKLRQDIENLTAQLKELPNSFKQYASFEHVRTLLKMYMKVNASIVELKSEAIKERHWRMLMRKLNV--SWSLNELQLGKVWDI--DLVKNEEIIREVLAIAQGEKALEEYLRQITEVWKNYVLELTNYQSKS----KIIKGWDDLFNKVKEHINNVTSMKASPYFKQFEEEATAWEDRLNKINALFDVWIDVQRRWIYLDGIFAGSADIKVLLPVESQRFQSVSTEFLGLMKKVQKSPLVTDVLNIANVQRQLERLADLLGKIQKSLGEYLERQRSSFPRFYFVGDEDLLEIIGNSXXXXXXXXXXXXMFAGVHSIILSEDEKVILGMMSKEGEELRFISPVSIIEHPRINDWLTAMEKEMRVSLAKYLNVAVKEISGWRTESNIDKDKFMVWLDKYQAQIVVLAAQITWSEAVEASLASGVSLESTMTVVHSTLNMLADTVLYEQPPVRRRKLEHLIIEYVHQRDVLRALHNDGVSSNKNFDWMSQMRFYFDPKQTDPLHQLSIHVANAKFHYGFEYLGVCDRLVQTPLTDRCYLTMTQALEARLGGSPFGPAGTGKTESVKSLGNQLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLSAVSQQIQGIQEALRELMVSKKDSINVELLGKQVHVNPDMAIFITMNP---GYAGRSNLPDNLKKLFRSLAMTQPDRQLIAQVMLYSQGFRTAEVLAGKVVPFFKLCDEQLSPQSHYDFGLRALKSVLVSAGNVKRDRIKQEKEKIVARGEEINETAIAEQLPEQEILIQSVMETMVPKLIADDIPLLYSLLTDVFPGVEYRQAEMKRLREELRKVSENKFLVYSDEPNTAGYLWVEKVLQLYQITTIHHGLMMVGPSGSGKTMACRVLLQALENIDGIEGVAHIIDPKSISKDSLYGYMDPNTREWTDGLFTHILRRIIDSVRGESNKRQWIVFDGDVDPEWVENLNSVLDDNKLLTLPNGERLAIPPNVRIMFEVQDLKYATLATVSRCGMVWFSEEVLTTGMILTHFL 7217 +N++ W F+ ++ Q I QV L+ + K ++ + ++ WE+ KP + GD EE + IQ ++ K + +L + RE ++K E + G++P + + ++ ++ W + ++ M + W+ + + D E L +++L + Q + ++ + +V++++ + + + HW + R L + ++ +L+ + + ++++N + ++++ + AQGE A+ + ++++T L +Y+ + KIIK W + N +K+ + S+K+SPY+ QF ++ WE RL ++ ++QR+WIYL+ IF A LP E+ RF V +E+ ++ V K + + + ++++ LE++ D L + QK+L ++LE++R++FPRFYF+GD+DLLEI+G S + + +Q H KK+F G++ + S + I+ M+S EGE + V I+ P++ WL + EMR +L AV + L KY +Q++ LA ++ +S ++E +L L S + + L A T + V KL+ LI++ +H DV+ L + S ++ W Q+RFY L Q+S ++F Y +EY G +LV TPLTD+CYLT+TQA+ LGG+P+GPAGTGKTESVK+L +GR VLVFNCDE D +MGRIF G+ + GAWGCFDEFNRL+ +LSAVS QIQ IQ A+ K + + GK V VNP+ AIF+T+NP GY GR +PDNLK+LFR++ M +PD +LI+ +LYS+GF A LA K+V F+L + LS Q HYD+GLRALK VL G ++R + + NET ++++Q+++ + KL D SL+ D+F V + + L E L ++ + D+ +EKV QLY+ G+++VG +GSGK+ ++L ++L V +PK++++ L G MD +TREW+DG+ T R V +++ WIV DGD+DPEWVE LNSVLDDN+LLT+P+GER+ NV +FE L++A+ ATVSR GM++ SEE +T I+ +L Sbjct: 971 DNLEQTWDRFELMLDGHQSMIKDQVEVLKSNVETSVKGMKDEAEKLKARWEQFKPRNDALQGD--REEMLKAIQFIKEKRVQWQQLSDGREKIEK-----ECGQFGLEPPKMDIIDEIDEDIKQFEDNWLIYEMFNNELDTMSQEEWIVFRSKTYLFD-EFLQKWMEKLKGTGSQTHMSVRLMKDVEHFKEVSSALKFCRGDVLSADHWHEMFRFLGLPRGTTIEKLKFADLLSVSKNIIENTDQLKQLNSRAQGEVAIRDAIQELTLWAAQTEFTLADYKHSNGQNLKIIKEWKESINSLKDSQALLQSLKSSPYYSQFTDKTAVWETRLADLDVFLAQMNEIQRKWIYLEPIFGRGA-----LPSEASRFSRVDSEYRAILNDVSKDARLVSLCSRQSLKKSLEQIVDQLNRCQKALNQFLEQKRTAFPRFYFIGDDDLLEILGQSTNPQVIQTHMKKLFQGINRVQFSSTGETIISMVSSEGETVPLSKAVRIV--PQVESWLQELSDEMRRTLKDLTAQAVADAQPS--------------LAKYPSQVLCLAEEVKFSASIENNLNGSSDLNSFKSQLLEKLK--AYTNMKVDDKVSDLKLKSLILDLIHHIDVVDQLLTNQAKSINSWTWQRQLRFYL-VNGGIVLRQVS-----SEFEYTYEYQGNYAKLVHTPLTDKCYLTLTQAMYMGLGGNPYGPAGTGKTESVKALAALMGRQVLVFNCDEGIDVTSMGRIFTGIVECGAWGCFDEFNRLDSTVLSAVSMQIQTIQGAI------KSRAGSCTFGGKNVQVNPNSAIFVTLNPAGKGYGGRQKMPDNLKQLFRAVVMGKPDNELISSTILYSEGFVDATALARKIVSVFQLSRQMLSKQQHYDWGLRALKVVLGGCGALRRTQTNK------------NET---------DLVVQALLLNTLSKLTFSDSERFNSLIDDIFSNVTKEMTKFEELVEPLGVAAQEMGIKLGDKQ-------MEKVFQLYEQMRQRIGVVVVGAAGSGKSTIWKILQRSLILTKKPLKVTQ-FNPKAVNRSKLLGNMDMDTREWSDGIITMAARE----VTKDTSVHHWIVCDGDIDPEWVEALNSVLDDNRLLTMPSGERIQFGSNVNFLFETDSLQFASPATVSRMGMIYISEEDVTPKDIVASWL 2071 HSP 2 Score: 596.275 bits (1536), Expect = 3.428e-170 Identity = 539/2101 (25.65%), Postives = 970/2101 (46.17%), Query Frame = 3 Query: 7794 VPTMDTVRHEALLYTWL--AEHRPVLLCGPPGSGKTMTLFSALRCLPDMEVVGLNFSSATTPELMLKTFDQYCEYRKTPNGIVLAPQQLNKWLIFFCDEINLPDMDKYGTQRVISFLRQMVEHHGFYRITDMQWVSFERIQFVGACNPPTDPGRKPLSHRFLRHVPVVYVDYPGETSLKQIYSTFNRAMLRMLPSLRGYADTLTNAMVEFFLKTQERFTHDMQPHYIYSPREMTRWVRGI--HEALKPLESLSVEGLVRIWAHEALRLFQDRLVEEDERHWTDD---NINEVALKHFPNINKEEALKRPILYSNWLSKDYSAVTQEELRDY---VKARLKVFYEEELDVPLVLFNQVLDHVLRIDRVFRQPQGHLLLIGVSGAGKTTLSRFVSWINGLSVFQVKVHNKYTAEDFDEDLRNVLRRSGCKGEKITFIMDESNVMDSSFLERMNTLLANGEVPGLFEGDELTTLMTQCKEGAIREGLMIDSQEELYKWFTQQICRNLHVVFTMNPSADGLKDKASTSPALFNRCVLNWFGDWSLEAYFQVGKEFTNRLDLERTDYKVPDTLPCIAEGLLPQNPI---YRDVVVNALVFVHQTMHQANVRVQKRGGRTAAITPRHYLDLIAHYMKLSAEKRADLEEQQLHLNNGLKKIEQTVDQVEVMQRSLTKKRQELENMNEAANAKLKQMVQDQQEAEQKKTTGQALKEELAKQEQFVNEKQKTVKQELDQVEPTVNEAKQAVQNIRKKDIQEIKAMKNPPNAVKMAVESICLLLGEKTTDWQSILKVIIKDTFVTSILNFNTDDVSDNTRETMKK--KYLSNPDYNFEK--VNKASNACGPMVKWVLAQISYADILKRVEPLRNELTELSDAAEQNRKKSQETEDLIAQLEKSIAKYTEEYATLISQAQTIKSDLASVESKVGRSVALLGSLSSERTRWDSGSETFKAQMATINGDCLLSSAFMAYGGYFDQHMRTSLFNTWCHHLSEADILFRSDLARVEYLSNPDDRLRWQANSLPADDLCVENAIILRRYNRYPLIIDPSGQATTFLLNEYKEKKITKTSFLDDSFRKTLESALRFGTPLLVQDVESYDPILNPVLNREVRRTGGRTLITLGDQDIDLSPTFTIFLSTRDPSVEFAPDICSRVTFVNFTVTRSSLQNQCLNAVLKIERPDIDQKRSDLLKAQGEFQLKLRHLEKDLLQSLNEAQGNLLENDKIIARLETLKREAADVAKKVEETDVVMQEVESVSTEYVPLAQSCSNIYFTLEAMNQIHFLYQYSLQLMLDIFSSVLINNPELTNVKAASDRLKIITKNLFQVTYNRLARGMLHEDQITFATILARIFLKGSTPIGFLENEFQHFLRSQEATITSSDSNKQDNLGLT-LHQDQIDSVKRLKKL--KVFAKIEEKVKSTKDIKNWTLTVTPESNVPELWVDDNNYNDE-KLSKIAKGMYNLLIIQAIRPDRLLASTQKFIASVLGDTFTESVR-GTLDLASIVEVEVTACVPILLCAVQGYDPSGRVEDLASEQGKQLTGIAIGSAEGFSQAEKAINSAAKTGKWVMLKNVHLATSWLVSLEKKIHSLQAHPNFRLFLTMEITPKLPVNLLRAGRVLVFEPPPGIKANLLRTLSSINNQRMSKEPVERSRLYFLLAWLNAIVQERLRYVPLGYSKKYEFGESDFKCALDTIDTWVDGAAMGRTNLPPEKIPWVALQTLLGSCIYGGKIDNAFDQRLLNSFLGYLFTEKCFDHNFA--LVSDADDGSNIAFPESTKHTDILQWVHKLPDLQTPSWLGLPNSAEKVLLTNLGQSLIGNILKMQQSLEDDEELVVGQSKTKRTIEVGDGRPAWMRQ---LYQSTQTWLQI-----LPKSVTPLQRTIENIKDPMYRCFEREVNSGCNLLASVRKDLEDVAEVCKGAKKPTNHHRSMMADLAKGIIPKMWIRYAIPPGLTVIQWIQDFADRIKQLLHISDTAAKSGVIALRSIQVWLGGLFMAEAYITATRQSVAQNNKWALEELFLDVELGEGKVDSNTCV-ITGLRLMGSEIVD-PRTLKLSTLIYKDIDICRLKWIRVEKSQQLEGSSAKDKVCLPIYLNAARSTVLFTL 13994 V T DT R+ ++ +WL L+ G G GK L + P+ ++ L S+ ++ +L+ Q C P G V P+ +I F INLP DKYGT +++ L+Q++ + GF+ +++WVS E IQFVG+ NP D +S+R + V ++ + L IY T+ +L + ++ + N MV+ + K Q F +++SPR++T WV + HE L+ +E ++ EA R+F DRL E+++ ++ N+ ++ + I KE+ S +T + D+ + + F E + L +Q+ IDRV P GHL L G G G+ R V+ ++ + VF V ++A+ FD +L+N + ++ E + I+++ + + FL+ +N+LLA+G VPGLF EL L+ E A + L ++ +I +HVV + A+ K + +PA+ C + F +R D + ++P + ++G+ + I + DV+VN +I P Y + ++ +L KR L + L G+ K+ + D+V MQ+ KK + L A+ LK + + AE +K + + LK K+ + E++ + ++L +V+P ++EA++AV +I+ + + EI++++ PP AV+ ++++ L +G T W+++ K + K I+NF+ + + T E KK + +FE+ +AS A P+ WV A + Y+ IL+++ PL E +L ++ K+ + + +++ + + ++ L+ +A IK DL + + + L+ SLS E RW ETF + + + L++SAF+ Y G + R SL + C + A +E ++L W+ LPAD L +EN IL PLIID SGQ + F L+++ EK T + D +E A+RFG +++ D+ +D L P+L +++ G R +I+ G + ID +P F I+ TRD V+ P+ ++ VNFT T S+L Q L+ + +E+P+++++ S LL+ +L+L LE+ LLQ L +QGNLLEN ++ L K A + K + E++ + +E+ + YVPL+ S+++F+ + + +Y YS+ ++ +F + + + +S R++ + + + + ++RG+ +D++ FA F+ + P F E++ F + +S L + + D++ S+ R++ +F + ++ ++ T+ E+ P+ N E K++ K +L IQA++P+RL F+ L S+ +L I + E + PIL G DPS + + AS I++G + + A +AI +A G+W+ L N+HL + S+ K + H NFRL+LT E + P +L+ + FEPPPG++ NLLRT + I+ S + V + F+LAWL+A++QER ++P G++K YEFG SD + A ++ L K W ++ +L IYGG+I+N FD ++L+S+L LF ++ + LV D + E H +P + P GLP NI Q +E D + + RT+ +GD + A Q + Q W ++ LPK P T DP+ E + +L+ + + + VA+ K + + + L P W P ++ + + L + +++ S +L S + LF ++ A RQ+ ++ K L++L L ++ + CV + GL L G+ R +S+ Y I L W E S + G +++ +P+Y ++ RS ++ ++ Sbjct: 2198 VQTADTQRYSDIIGSWLQSGNRESFLITGTTGCGKQQLLKHCFQNDPESQLASLYCSAQSSSSHLLQLIQQNCVQASNPTGRVWRPKDRPN-MILFLKGINLPAPDKYGTNELLALLQQLLTYQGFFD-HNLEWVSIENIQFVGSMNPIGDGAAVSISNRLFSLLRCVSLNTTDSSQLTSIYRTYLTPILEEVGERN--SEIIANRMVDIYNKVQSNFRPTDSVVFLFSPRDLTNWVVSLLRHE----LDQGKLEAVI---CFEARRIFADRLPTENDKLKFEEILRNVIPISQANETVIFKEKVYVTTGTVVPGESNTGLPLTPINMSDFNQLLAKSINRFAFEIANFNCPLTSQLAFFCACIDRVLTGPGGHLFLPGRPGFGRRDSVRLVAHMHNIQVFSPPVTANFSAKQFDNELKNAITQAVTNNEHVVLILEDHQLRKNIFLQAINSLLASGNVPGLFTQQELDGLVALVSEAANQASFT----GALQQFLAHRIRSLVHVVLILEVEANDFKINITENPAILKHCNVI----------------FADRFD-RNSLVEIPK-IQMESQGITTTDAILTGFNDVLVNL-------------------PEHLSIQPIKYRQFVENFFQLLGYKRLTLSVRLERLKGGVSKLNEARDEVAKMQKKAGKKSKLLAEKQAEADEALKAITESMSGAEDQKLSMEQLKAATEKENVRIEEQKAKIDEQLKEVQPLIDEARRAVGSIKSESLSEIRSLRAPPEAVRDILQAVLLFMGILDTSWEAMRKFLSKSGVKDDIMNFDANRI---TNEIHKKVTALVKQKSNSFEEANAKRASAAAAPLAAWVKANLEYSKILEKIAPLEGEKNKLVKNLKKAEKQMENLSKGLQSVDEVVGELKRKFEVLMKEATQIKVDLDREQDTIRIAGTLVESLSGEFERWKIQIETFGEEQSKMELCSLITSAFITYLGGCSEKDRKSLLKSMCKMFNMPPTFKPLSFASLE-----TEQLNWKTKGLPADQLSLENGSILFTSCHAPLIIDRSGQVSLF-LSKFLEKSETFKAAQPD-LMTQIELAIRFGKTIIIDDIVEFDSALIPILRKDLSSQGPRQVISFGGKSIDFNPDFKIYFCTRDEKVDIRPNSYVQLNIVNFTTTISALSAQLLDVAIHLEKPELEERSSSLLRDAELKKLELEGLEQLLLQQLASSQGNLLENTALLDSLNKSKESAEIITKSIVESEQLHKELTTQKDIYVPLSLFTSSLFFSFSNLQFHNPMYNYSVNTIMHLFGKTIKSCED-----KSSTRVETLARQMQLTVFYHISRGIFRQDRLMFAV----AFINATMPKMFQPKEWELF-----TGVLVDESTDLSALRVQWISPDRLQSLARIRTHLPSLFNNFQ--IQDDATWNEFSKTLQCENAFPK--------NVELKMTHFQK----VLFIQAVKPERLYNCLMDFVLKTLN---IPSINPPAFELKHIFQ-ESESTEPILFILADGADPSQELSEFASSMNVPYHSISMGQGQEIA-AYEAIRESASKGEWLCLNNLHLMLQAVPSIFKHLSLTTPHENFRLWLTTEGDARFPSMMLQQSLKITFEPPPGVRNNLLRTYTQIDR---STKNVITCQSIFVLAWLHALLQERRTFIPQGWTKFYEFGASDVRVAKSFVE-----------QLTANKADWEFVRGILKFVIYGGRIENDFDFKVLDSYLNVLFCDEKINGRAGSQLVKGIDLLATTNVQEYIGHIS-----KSVPSVDEPYLFGLPE----------------NIKYSWQIVEADRTI-----SSIRTLALGDTKNALSDQSDKISQIVSLWKKLCQSDDLPKRELP---TAIRSADPISEVLCLETINALSLIKQLHRSIGHVAKSMKTPSLASPAVQKTIQSLVFQQTPDEWDSMWAGPS-DPADYLNVVVKKTRGTLQLFESSKSS---SLLSSPIDFSDLFYPNIFLNALRQTTSRQIKIPLDQLILSSAWTPSQLPAKQCVQVQGLLLQGATFDSFLRETTVSSAAYSQAPIVFLAWTS-ESSSTITG----EQIQVPVYSSSERSDLICSV 4151
BLAST of Cytoplasmic dynein 1 heavy chain 1 vs. Ensembl Celegans
Match: dhc-3 (Dynein Heavy Chain [Source:UniProtKB/TrEMBL;Acc:G5EDV4]) HSP 1 Score: 109.383 bits (272), Expect = 7.257e-23 Identity = 81/332 (24.40%), Postives = 167/332 (50.30%), Query Frame = 3 Query: 9621 LDLIAHYMKLSAEKRADLEEQQLHLNNGLKKIEQTVDQVEVMQRSLTKKRQELENMNEAANAKLKQMVQDQQEAEQKKTTGQALKEELAKQEQFVNE---KQKTVKQE----LDQVEPTVNEAKQAVQNIRKKDIQEIKAMKNPPNAVKMAVESICLLLGEKTTD------------WQSILKVIIKDTFVTSILNFNTDDVSDNTRETMKKKYLSNPDYNFEKVNKASNACGPMVKWVLAQISYADILKRVEPLRNELTELSDAAEQNRKKSQETEDLIAQLEKSIAKYTEEYATLISQAQTIKSDLASVESKVGRSVALLGSLSSERTRW 10559 L +++ KL+ +KR ++ + G++K+++ +QV MQ L + + +L + + + + ++ + E + E +A E NE K +++K E L P + A +A++ + + D+ +K M+ PP AV++ +E++C+LLG K W S K++ F+ I +F D VS T + +++KYLS +++ E V + S A + +WVLA Y I K VEP R L + +Q+ K+ + + ++ + + +++++ + + Q ++S ++S E ++ R+ L+ +LS E+ +W Sbjct: 2101 LKMVSTITKLAKKKREEVRKTMTKYEKGMEKMKRAEEQVAGMQGELLRLQPQLVRTSIETSMLMSTIEKETIDVENAR-------EVVAANENKANEAATKAQSLKAESEAELASAIPALESAVEALETMTQSDVSSLKTMRFPPYAVRLCMEAVCILLGVKPAKITNEIGEVVNDYWVSGQKLLSDIHFLAKIRSFARDTVSKKTVKLIREKYLSKEEFDPENVKQCSLAAEGLCRWVLAIDMYNQISKIVEPKRERLRKAEVLVKQHLKQLEVKRKALLKVTEKLQGLSDQFSQMCQKKQELESQISSCEVRMERAERLVQALSGEKDKW 2425 HSP 2 Score: 96.2857 bits (238), Expect = 7.002e-19 Identity = 134/696 (19.25%), Postives = 309/696 (44.40%), Query Frame = 3 Query: 3936 VNIIQILEGKFNRLKEERENVQKAKEA--------LELTEIGVKPISEEKVTNALSELHDL--KNVWNELKSIWEKIRDMKETPWLSVQPRKL---RQDIENLTAQLKELPNSFKQYASFEHVRTLLKMYMKVNASIVELKSEAIKERHWRMLMRKLNVSWSL--NELQLGKVWDIDLVKNEEIIREVLAIAQGEKALEEYLRQITEVWKNYVLELTNYQSKSKIIKGWDDLFNKVKEHINNVTSMKASPYFKQFEEEATAWEDRLNKINALFDVWIDVQRRWIYLDGIFAGSADIKVLLPVESQRFQSVSTEFLGLMKKV-QKSPLVTDVLNIANVQRQLERLADLLGKIQKSLGEYLERQRSSFPRFYFVGDEDLLEIIGNSXXXXXXXXXXXXMFAGVHSIILSEDEKVILGMMSKEGEELRFISPVSI-IEHPRINDWLTAMEKEMRVSLAKYLNVAVKEISGWRTESNIDKDKFMVWLDKYQAQIVVLAAQITWSEAVEASLASGVSLESTMTVVHSTLNMLA----DTVLYEQP-----PVRRRKLEHLIIEYVHQRDVLRALHNDGVSSNKNFDWMSQMRFYFDPKQTDPLHQLSIHVANAKFHYGFEYLGVCDRLVQTPLTDRCYLTMTQALEARLGGSPFGPAGTGKTESV---KSLGNQLGRFVLVFNCDETFDFQAM--GRIFVG 5930 +N +Q ++ K L EER + KAK+ L L + + KV S+L L K + + + +I D+ L ++ +L + D++ A +KE + K+ + + +L + K+ + + +A+K+RHW+M+++ S + N L + ++ +++ ++ + +V A A+ E+ LE + ++ W +Q + +L +++ H+ ++ +SP+ + W D L +N ++ RW ++G+F+ + DI +P E + F+ +S +L + ++ ++ P++ + + + +L L L G+++ YL ++R+ FPR + + DE +L +I +S++ + + +F + + ++ K+ + +S + E + + PV++ + + W+ ++ +++ +L + + +++++ + + + Q V L TW +E S+ ++++T++ S L + VL++ PV L H+ Y ++ L N+ V ++ W SQ+R+Y+ L + I V Y +E GV D ++ L D +A++ + + FG G V + + LG+ + + ++ D + + G + G Sbjct: 563 INEVQKVQIKMGNL-EERSAILKAKDEKLIGQRSLLGLLSSPIDCVRIAKVCEFFSKLSTLHFKTLLHHESCLRMRISDVDHNS-LVIETERLQSEKNDLKEKAAVIKEHETTSKE--ALLKIEIVLAEFEKLLPVLGAISCQAMKDRHWKMILQDSETSVKVEGNPL-VSELLEMNFIEKADKFEQVGAQAEKERVLETSIEKMKSQW--VTATFVTHQGGELLTT---ELNVQMQAHLARSQTILSSPHAFSILDHIRHWLDTLLNLNTFVHLYKQCDTRWRKIEGVFS-TEDIAYQMPHEFRTFKKISLRWLHINNQITEERPILEQMDLVQQLNLELSELEVLFGRMENGFHAYLRKKRAVFPRLFALSDELVLSLICDSREPANCKSYIPLLFPSLTT--FDQNTKMEIISVSTKLETISLVKPVNVNLSKRHVEKWMHELDSQIKYTLRTRIRLLIEKMNYKLSPVE------TILNEPIQVAAVYLKIAFTWQ--MENSMK-----QNSLTILASELKICIRDCQHAVLHKHDRWEFLPV----LYHI---YKSSTHLVNKLMNEQVIFIDDYRWTSQLRYYWH------LENVFIRVGTVSTRYDYEVQGV-DCMIDNQLVD-------EAVKYFICMNHFGFNGFVNGMDVNLARQIAGALGKPFAICDTEQEIDCKMLIEGALLFG 1211
BLAST of Cytoplasmic dynein 1 heavy chain 1 vs. Ensembl Fly
Match: Dhc64C (gene:FBgn0261797 transcript:FBtr0073359) HSP 1 Score: 6095.77 bits (15813), Expect = 0.000e+0 Identity = 2933/4636 (63.27%), Postives = 3659/4636 (78.93%), Query Frame = 3 Query: 240 LSEPQNEECLTKFINDNQVTTLTIQQT--------KRXXXXXXXXXXXXKISNEVNFESNKSQTSIFIKNNQVIEADKTISSQLQVLSYCDGPPFETMHSLVCYGLLPYFXXXXXXXXXXXXXXXXXMVPSVEKKIAELEIGLLHLQQNIEIPEITLTPHPYVAHIIQEKLLQNKEARVSDFEDKFEDTQFLNQLQAGVNRWIKEIQKVTKLNRDPSTGTALQEISFWLNLEHSLDKIQEKRESLEVALTLAILKQAKRFHATTSFDTDTALSSAKIQVKDYNQLMKDFPINDLLSASQLDKISEALQQIFSHLKKVRATKYPVNRIIKLMEALSRDLTTQLMKVISNMHLMSMPYDEFEKIFTACQQVFSTWEDEYDKMQNLLRDIAKKKREEFTKFAWKMNATHKKLQTRLENIKKFRYQHEQLRQVIVRVLKPVTKVVPSVEAGVPKDQITDKGDKSSTFLP---ESADTSSIDEVNAAYEIVKVIDCLDFAKEENDEWDAAIKRYEERIDRVESRIASHLRDLLGQSKNANEMFRYFSRFNALFVRPHIRGAIGEYQTQLIQRVKDDIEALHNKFKVQYASSTACKMSKVRDLPPVSGSIIWVRQILRQLNAYMKRVEDVLGKDWAQHIEGQKLKADGESFKLKLNTSELFEEWSKKVAEKSLSVAGSIFNVESTRTVVTVRDREPQKITVLKLKVNFLPDVITLAKEVRNMRALGFRTPLSIVNKAHSANQLYPFAISLIESVRTYESTCSKIEEHKMQNISLLTAGLRKDVQLCIHEGVQITWESYRLDQYVQKLAELVFSFQEKVDDLVIVIKEIDFNVKALETCSYNKQTFEEILIRIQEAVDNMSLHQFSNLAQWVSNLDSLVEQRLIVRLEAGLLEWIKVLKGXXXXXXXXXXXXXXXVNSMAKHRLGGKPQIKKLIHELRITNQQMHLYPSIEVATQDILYQMSSWQNIILNLSRIVHSRYQVGLETESDNQKTYKKLLSSLPNSGESLENAYAAVHNILRDANEYVKTWTNYQSLWDLQGDQLFSLIADDNTVWMNVLEEIKSMRKHFDVAETQKEFGPLVIAFGKVQSKVSMKYDNWHKEVLTKFGQNMGKMMTTLYNEVQRARNELEQQSIDSGGTNESVNFITYTQNIKRKMNTWEKQAEACRAGQNILCRDRFQFPNDWLDSENIQGEWSAFKEIMRRKQETISSQVASLQMKITEEDKIVESKTTEVLGNWEKDKPIAGDLTPEEAVNIIQILEGKFNRLKEERENVQKAKEALELTEIGVKPISEEKVTNALSELHDLKNVWNELKSIWEKIRDMKETPWLSVQPRKLRQDIENLTAQLKELPNSFKQYASFEHVRTLLKMYMKVNASIVELKSEAIKERHWRMLMRKLNVSWSLNELQLGKVWDIDLVKNEEIIREVLAIAQGEKALEEYLRQITEVWKNYVLELTNYQSKSKIIKGWDDLFNKVKEHINNVTSMKASPYFKQFEEEATAWEDRLNKINALFDVWIDVQRRWIYLDGIFAGSADIKVLLPVESQRFQSVSTEFLGLMKKVQKSPLVTDVLNIANVQRQLERLADLLGKIQKSLGEYLERQRSSFPRFYFVGDEDLLEIIGNSXXXXXXXXXXXXMFAGVHSIILSEDEKVILGMMSKEGEELRFISPVSIIEHPRINDWLTAMEKEMRVSLAKYLNVAVKEISGWRTESNIDKDKFMVWLDKYQAQIVVLAAQITWSEAVEASLASGVS------LESTMTVVHSTLNMLADTVLYEQPPVRRRKLEHLIIEYVHQRDVLRALHNDGVSSNKNFDWMSQMRFYFDPKQTDPLHQLSIHVANAKFHYGFEYLGVCDRLVQTPLTDRCYLTMTQALEARLGGSPFGPAGTGKTESVKSLGNQLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLSAVSQQIQGIQEALRELMVSKKDSINVELLGKQVHVNPDMAIFITMNPGYAGRSNLPDNLKKLFRSLAMTQPDRQLIAQVMLYSQGFRTAEVLAGKVVPFFKLCDEQLSPQSHYDFGLRALKSVLVSAGNVKRDRIKQEKEKIVARGEE-INETAIAEQLPEQEILIQSVMETMVPKLIADDIPLLYSLLTDVFPGVEYRQAEMKRLREELRKVSENKFLVYSDEPNTAGYLWVEKVLQLYQITTIHHGLMMVGPSGSGKTMACRVLLQALENIDGIEGVAHIIDPKSISKDSLYGYMDPNTREWTDGLFTHILRRIIDSVRGESNKRQWIVFDGDVDPEWVENLNSVLDDNKLLTLPNGERLAIPPNVRIMFEVQDLKYATLATVSRCGMVWFSEEVLTTGMILTHFLNELKKVQVMEGEEDFSVNQGDTGADADSKISSSPIIQLQTQVSSILAPFFTEDGLIAKCLDYSTTLEHIMDFTRLRALTSLFSMIKQSIRNMIEYNQSHSDFPLNNEQIENYVAKSLISSVVWSMSGDSKLKVREQLSQYIKNISTVDLPTVGGIKNIIDFEVNIQGTWVAWSNKVPQIEVETHKITATDVVVPTMDTVRHEALLYTWLAEHRPVLLCGPPGSGKTMTLFSALRCLPDMEVVGLNFSSATTPELMLKTFDQYCEYRKTPNGIVLAPQQLNKWLIFFCDEINLPDMDKYGTQRVISFLRQMVEHHGFYRITDMQWVSFERIQFVGACNPPTDPGRKPLSHRFLRHVPVVYVDYPGETSLKQIYSTFNRAMLRMLPSLRGYADTLTNAMVEFFLKTQERFTHDMQPHYIYSPREMTRWVRGIHEALKPLESLSVEGLVRIWAHEALRLFQDRLVEEDERHWTDDNINEVALKHFPNINKEEALKRPILYSNWLSKDYSAVTQEELRDYVKARLKVFYEEELDVPLVLFNQVLDHVLRIDRVFRQPQGHLLLIGVSGAGKTTLSRFVSWINGLSVFQVKVHNKYTAEDFDEDLRNVLRRSGCKGEKITFIMDESNVMDSSFLERMNTLLANGEVPGLFEGDELTTLMTQCKEGAIREGLMIDSQEELYKWFTQQICRNLHVVFTMNPSADGLKDKASTSPALFNRCVLNWFGDWSLEAYFQVGKEFTNRLDLERTDYKVPDTLPCIAEGLLPQNPIYRDVVVNALVFVHQTMHQANVRVQKRGGRTAAITPRHYLDLIAHYMKLSAEKRADLEEQQLHLNNGLKKIEQTVDQVEVMQRSLTKKRQELENMNEAANAKLKQMVQDQQEAEQKKTTGQALKEELAKQEQFVNEKQKTVKQELDQVEPTVNEAKQAVQNIRKKDIQEIKAMKNPPNAVKMAVESICLLLGEKTTDWQSILKVIIKDTFVTSIL-NFNTDDVSDNTRETMKKKYLSNPDYNFEKVNKASNACGPMVKWVLAQISYADILKRVEPLRNELTELSDAAEQNRKKSQETEDLIAQLEKSIAKYTEEYATLISQAQTIKSDLASVESKVGRSVALLGSLSSERTRWDSGSETFKAQMATINGDCLLSSAFMAYGGYFDQHMRTSLFNTWCHHLSEADILFRSDLARVEYLSNPDDRLRWQANSLPADDLCVENAIILRRYNRYPLIIDPSGQATTFLLNEYKEKKITKTSFLDDSFRKTLESALRFGTPLLVQDVESYDPILNPVLNREVRRTGGRTLITLGDQDIDLSPTFTIFLSTRDPSVEFAPDICSRVTFVNFTVTRSSLQNQCLNAVLKIERPDIDQKRSDLLKAQGEFQLKLRHLEKDLLQSLNEAQGNLLENDKIIARLETLKREAADVAKKVEETDVVMQEVESVSTEYVPLAQSCSNIYFTLEAMNQIHFLYQYSLQLMLDIFSSVLINNPELTNVKAASDRLKIITKNLFQVTYNRLARGMLHEDQITFATILARIFLKGSTPIGFLENEFQHFLRSQEATITSSDSNKQDNLGLTLHQDQIDSVKRLK-KLKVFAKIEEKVKSTKDIKNWTLTVTPESNVPELWVDDNNYNDEKLSKIAKGMYNLLIIQAIRPDRLLASTQKFIASVLGDTFTESVRGTLDLASIVEVEVTACVPILLCAVQGYDPSGRVEDLASEQGKQLTGIAIGSAEGFSQAEKAINSAAKTGKWVMLKNVHLATSWLVSLEKKIHSLQAHPNFRLFLTMEITPKLPVNLLRAGRVLVFEPPPGIKANLLRTLSSINNQRMSKEPVERSRLYFLLAWLNAIVQERLRYVPLGYSKKYEFGESDFKCALDTIDTWVDGAAMGRTNLPPEKIPWVALQTLLGSCIYGGKIDNAFDQRLLNSFLGYLFTEKCFDHNFALVSDADDGS----NIAFPESTKHTDILQWVHKLPDLQTPSWLGLPNSAEKVLLTNLGQSLIGNILKMQQSLEDDEELVVGQSKTKRTIEVG---DGRPAWMRQLYQSTQTWLQILPKSVTPLQRTIENIKDPMYRCFEREVNSGCNLLASVRKDLEDVAEVCKGAKKPTNHHRSMMADLAKGIIPKMWIRYAIPPGLTVIQWIQDFADRIKQLLHISDTAAKSGVIALRSIQVWLGGLFMAEAYITATRQSVAQNNKWALEELFLDVELGEG--KVDSNTCV--ITGLRLMGSEIVDPRTLKLSTLIYKDIDICRLKWIRVEKSQQLEGSSAKDKVCLPIYLNAARSTVLFT--LYFSTTDSSYDFYKRGVAI 14048 L +P N++ + KF++D QV L +Q+ + E E + + ++ISN+V+F +++ + IK V+EADK+I SQL+++++ DG P+ET+H+ + L PYFKSY+K+ G+ M PSVEKK+AELE+GLLHLQQNI+IPEITLT H V ++I++ +N++A+V+DF DK ED+ FLN LQ GVNRWI EI+KVTKLNRDP +GTALQEISFWLNLE +L +IQEKRES EVALTL ILK KRFHAT SFDTDT L A V DYN LMKDFPINDLLSA++L+KI A+QQIF+HL+KVR TKYP+ R +KL+EA+SRDL+ QL+KV+ LM +P+DEFE++ C ++FS W+DEYDK+Q LLRDI KKKR+E K W+++ HKKLQTR+E+++KFR QHEQLR VI+RVL+P K + D G+ T P ++AD ++I+EVN AYE VK +DCLD KE ++ W+AA+KRYEE+IDRVE+RI +HLRD LG +KNANEMFR FSRFNALFVRPHIRGAI EYQTQLIQRVKDDIEALH KFKVQY S +C++S VRDLPPV+GSIIW RQI QL Y+KRVEDVLGK W HIEGQKLKADG+SF+ KL+ S++F EW++KV E++ G IF +ESTR+ + + VL+L+VNFLP++ITLAKEVRN++ LGFR PL+IVNKAH ANQ+YP+AISLIESVRTYE T KIE+ +I L AGLRKDV + EG+ + WESY+LD YV +L+E V FQEKVDDL++V +++D +V++LETC Y+ TF EIL +IQ AVD++SL Q+SNL+ WV+ LD VE++L +RL+AG+ W + L G +E + + H+LGG PQI+ +HE+RITNQQM+LYPSIE A I+ Q +WQ I+ + R+ +RYQVGLE +TY+ LL+ LP G+ LENAY A+ + + YV W YQSLWDLQ D L+ + +D +W+ L +IK R FD ++T++ +GP++I + KVQ+KV++KYD+WHKE L KFG +G MT+ +++V ++R +LE QSI++ T+++V+FITY Q++K+ M W+KQ E R Q IL R RFQFPN WL +NI+GEWSAF EI++RK I +QVASLQ KI EDK VE++T + L +WEK KP G + P++A+ +QI E K++RLKEER+NV KAKEALEL E V S E++ AL EL DL+ VW+EL +W +I + +E PWLSVQPRKLRQ +E + AQLKELP + Y S+E+V+ L++ Y+KVN IVELKS+A+KERHW+ L ++L V+W L++L LG+VWD++L KNE I+++++ +AQGE ALEE+L+Q+ E W+NY L+L NYQ+K +II+GWDDLFNKVKEHIN+V +MK SPY+K FEEEA WE++LN+INALFDVWIDVQRRW+YL+GIF+GSADIK LLPVE+ RFQS+S+EFLGLMKKV KSP V DVLNI VQR LERLADLLGKIQK+LGEYLER+R+SFPRFYFVGDEDLLEIIGNSK++ +LQKHFKKMFAGV +I+L+E+ VILG+ S+EGEE+ F++PVS +EHP+IN+WL+ +EK+MR +LA L AV++I +R + ID +M W DKYQAQIVVLAAQI WSE VE++L ++ + V STLN+LAD+VL EQPP+RRRKLEHLI E+VH+R V R L N+GV+S K+F W+ +MRFYFDP+QT+ L QL+IH+ANA+F YGFEYLGV DRLVQTPLTDRCYLTMTQALE+RLGGSPFGPAGTGKTESVK+LGNQLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLSA SQQIQ IQEAL+ M S K+SI VEL+GKQV V+PDMAIFITMNPGYAGRSNLPDNLKKLFRSLAMT PDRQLIA+VML+SQGFR+AE LA K+VPFFKLCDEQLS QSHYDFGLRALKSVL+SAGNVKRDRI + KE++ RG+E I+E ++AE LPEQEILIQSV ETMVPKL+A+DIPLL+SLL+DVFP V Y +AEMK L+EE+RKV + +LV E + G W+EKVLQLYQI+ ++HGLMMVGPSGSGK+ A + LL+ALE +G+EGVAH+IDPK+ISK++LYG +DPNTREWTDGLFTHILR+IID+VRGE NKRQWI+FDGDVDPEWVENLNSVLDDNKLLTLPNGERL++PPNVR+MFEVQDLK+ATLATVSRCGMVWFSE+VL+T MI ++L+ L+ + + +G+EDF G D + SP +Q+Q ++ +L PFF+ DG++ + L+Y+ EHIMDFTRLRAL+SLFSM+ Q+ RN++ +N H DFP + +Q+E+Y+ K+L+ SV+WS +GD+KLKVR L ++++++TV LP G IID+EVN+ G WV WSNKVP IEVETHK+ + D+VVPT+DTVRHE+LLYTWLAEH+P++LCGPPGSGKTMTLFSALR LPDMEVVGLNFSSATTPEL+LKTFD YCEYRKTPNG+VL+P Q+ KWL+ FCDEINLPDMD YGTQRVISFLRQ+VEH GFYR +D WVS ERIQFVGACNPPTDPGRKPLSHRFLRHVP++YVDYPGETSLKQIY TF+RAMLR++P+LRGYA+ LTNAMVEF+L +Q+RFT DMQPHY+YSPREMTRWVRGI EA++PL+SL VEGLVR+WAHEALRLFQDRLV++ ER WT++NI+ V KHFP IN+EEAL+RPILYSNWLSKDY V +EELR+YV ARLKVFYEEELDVPLVLF++VLDHVLRIDR+FRQPQGHLLLIGVSGAGKTTLSRFV+W+NGLS+FQ+KVHNKYT+EDFDEDLR VLRRSGCK EKI FI+DESNV+DS FLERMNTLLANGEVPGLFEGDE TTLMTQCKEGA REGLM+DS +ELYKWFTQQ+ RNLHVVFTMNPS DGLKD+A+TSPALFNRCVLNWFGDWS A FQVGKEFT R+DLE+ ++ PD P + L+P NP +RD V+N+ V+VHQT+HQAN R+ KRGGRT A+TPRHYLD I H++KL EKR+DLEEQQLHLN GL KI +TV+QVE MQ+SL K+QEL+ NEAANAKLKQM QDQQEAE+KK Q ++ LA Q + EK+K V +L QVEP V +A+ AV++IRK+ + E++ M NPP+ VK+A+ESICLLLGE TDW+SI VI+++ F+ SI+ NF T++++D+ RE MK KYLSNPDYNFEKVN+AS ACGPMVKW +AQI YAD+LKRVEPLR EL L + A+ N ++ET+DL+ QLE+SIA Y EEYA LISQAQ IK+DL +V++KV RS+ALL SL+ ER RW+S SETFK+QM+TI GD LLS+AF+AYGGYFDQH R +LF TW HL A I +R+D+AR EYLSNPD+RLRWQAN+LP DDLC ENAI+L+R+NRYPLIIDPSGQATTFLLNEY KKITKTSFLDDSFRK LESALRFG PLLVQDVE+YDPILNPVLNRE+RRTGGR LITLGDQDIDLSP+F IFLSTRDP+VEF PDICSRVTFVNFTVTRSSLQ+QCLN VLK ERPDID+KRSDLLK QGEF+L+LR LEK LLQ+LN+A+G +L++D +I LETLK+EA D+ +KV+ETD V+ E+E+VS +Y+PL+ +CSNIYFT++++NQ+HFLYQYSL++ LDIFS+VL NNP+L S+RL I+T++LFQV Y R+ARGM+H D++TFA ++ +I LKG++ L+ EF FLRS+E + +N GL+ +QI+SV RL +L +F K+ EKV+S ++ W +PE VP+LW + + LS IA ++ LL+IQA RPDR++A+ + +VLG+ F + LD S+V+ ++ P LLC+V G+D SGRV+DLA+EQ KQ++ IAIGSAEGF+QAE+AIN A KTG+WV+LKNVHLA WLV LEKK+HSLQ H FRLFLTMEI PK+PVNLLRAGR+ VFEPPPGI+ANLLRT S++ RM K P ER+RLYFLLAW +AIVQERLRYVPLG++KKYEF ESD + A DT+DTW+D AMGRTNLPPEK+PW AL TLL IYGGKIDN FDQRLL SFL LFT + F+ +FALV++ D S +I P+ T+ L+W+ L D QTPSWLGLPN+AEKVLLT G L+ +LKMQQ LEDD+EL VG DGRP+WM+ L+ S WL++LPK++ L+RT+ENIKDP+YR FEREV SG LL +V DL+DV +C+G KK TNHHRSM+++L +GIIPK W RY +P G TVIQWI DF++R++QL +S +++G L+ VWLGGL EAYITATRQ VAQ N W+LEEL LDV + + K D C +TGL+L G++ + L L++ I D+ + LKWI++ ++ K+ LP+YLN+ R+ +LFT L + S+ FY+RGVA+ Sbjct: 52 LDDPVNQDTIRKFLSDPQVQALYVQRNCIKEDDSEQPAEGEDEKEQVTYQISNDVHFTNSRMASLACIKRGLVVEADKSIHSQLRLINFSDGSPYETLHAFISKSLAPYFKSYVKESGRADRDGDK-MAPSVEKKLAELEMGLLHLQQNIDIPEITLTAHQTVNNVIRKCAEENRKAKVADFGDKVEDSSFLNLLQNGVNRWIAEIKKVTKLNRDPGSGTALQEISFWLNLERALYRIQEKRESPEVALTLDILKHGKRFHATVSFDTDTGLKQALATVADYNPLMKDFPINDLLSATELEKIRPAVQQIFAHLRKVRNTKYPIQRCLKLIEAISRDLSQQLLKVLGTRRLMHIPFDEFERVMNQCFEIFSCWDDEYDKLQGLLRDIVKKKRDEHLKMVWRVSPAHKKLQTRMEHMRKFRRQHEQLRTVILRVLRPT------------KPAVGDDGNVVETKQPYSLDAADANAIEEVNLAYENVKEVDCLDITKEGSEAWEAAVKRYEEKIDRVETRITAHLRDQLGTAKNANEMFRIFSRFNALFVRPHIRGAIREYQTQLIQRVKDDIEALHEKFKVQYPQSKSCRLSSVRDLPPVAGSIIWARQIDNQLTMYLKRVEDVLGKGWETHIEGQKLKADGDSFRAKLSISDVFHEWARKVQERNFGSTGRIFTIESTRSRIG-------RGNVLRLRVNFLPEIITLAKEVRNIKNLGFRVPLTIVNKAHQANQIYPYAISLIESVRTYERTLEKIEDRA--SIVPLVAGLRKDVLNLVSEGIGLIWESYKLDPYVIRLSECVTQFQEKVDDLLVVEEQLDVDVRSLETCPYSAATFVEILSKIQHAVDDLSLRQYSNLSVWVTRLDEEVEKKLALRLQAGIQAWTEALTGNKKEVDTSMDTD---APAQPTHKLGGDPQIQNAVHEIRITNQQMYLYPSIEEARFQIMQQFFAWQAIVTSQVRLQSTRYQVGLEKHVS--QTYRNLLTKLP-EGKILENAYGAIEQKVSEVRNYVDEWLRYQSLWDLQADMLYGRLGEDVNLWIKCLNDIKQSRTTFDTSDTRRAYGPIIIDYAKVQAKVTLKYDSWHKEALGKFGTLLGTEMTSFHSKVSKSRTDLEMQSIEAASTSDAVSFITYVQSLKKDMIAWDKQVEVFREAQRILERQRFQFPNTWLHVDNIEGEWSAFNEIIKRKDTAIQTQVASLQAKIVAEDKAVETRTVDFLNDWEKTKPTGGKIRPDDALQQLQIFESKYSRLKEERDNVVKAKEALELQESAVPNNSAERMNVALEELQDLRGVWSELSKVWTQIDETREKPWLSVQPRKLRQQLEAMMAQLKELPARLRMYESYEYVKKLIQSYIKVNMLIVELKSDALKERHWKQLTKQLRVNWVLSDLSLGQVWDVNLQKNEGIVKDIILVAQGEMALEEFLKQVRESWQNYELDLINYQNKCRIIRGWDDLFNKVKEHINSVAAMKLSPYYKVFEEEALTWEEKLNRINALFDVWIDVQRRWVYLEGIFSGSADIKTLLPVETSRFQSISSEFLGLMKKVTKSPKVMDVLNIPAVQRSLERLADLLGKIQKALGEYLERERTSFPRFYFVGDEDLLEIIGNSKNIARLQKHFKKMFAGVAAILLNEENNVILGISSREGEEVHFMNPVSTVEHPKINEWLSLVEKQMRFTLASLLAQAVQDIKQFR-DGKIDPQAYMEWCDKYQAQIVVLAAQILWSEDVESALQQASENNQSKPMQRVLGNVESTLNVLADSVLQEQPPLRRRKLEHLINEFVHKRTVTRRLLNNGVTSPKSFQWLCEMRFYFDPRQTEVLQQLTIHMANARFFYGFEYLGVQDRLVQTPLTDRCYLTMTQALESRLGGSPFGPAGTGKTESVKALGNQLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLSACSQQIQTIQEALKYEMDSNKESITVELVGKQVRVSPDMAIFITMNPGYAGRSNLPDNLKKLFRSLAMTTPDRQLIAEVMLFSQGFRSAEKLACKIVPFFKLCDEQLSNQSHYDFGLRALKSVLISAGNVKRDRIMKIKEQMKQRGDENIDEASVAENLPEQEILIQSVCETMVPKLVAEDIPLLFSLLSDVFPNVGYTRAEMKGLKEEIRKVCQEDYLV-CGEGDEQGAAWMEKVLQLYQISNLNHGLMMVGPSGSGKSTAWKTLLKALERFEGVEGVAHVIDPKAISKEALYGVLDPNTREWTDGLFTHILRKIIDNVRGEINKRQWIIFDGDVDPEWVENLNSVLDDNKLLTLPNGERLSLPPNVRVMFEVQDLKFATLATVSRCGMVWFSEDVLSTEMIFENYLSRLRSIPLEDGDEDFV---GVIKPAKDKEEEVSPSLQVQRDIALLLLPFFSADGIVVRTLEYAMDQEHIMDFTRLRALSSLFSMLNQAARNVLTFNAQHPDFPCSADQLEHYIPKALVYSVLWSFAGDAKLKVRIDLGDFVRSVTTVPLPGAAGAP-IIDYEVNMSGDWVPWSNKVPVIEVETHKVASPDIVVPTLDTVRHESLLYTWLAEHKPLVLCGPPGSGKTMTLFSALRALPDMEVVGLNFSSATTPELLLKTFDHYCEYRKTPNGVVLSPVQIGKWLVLFCDEINLPDMDSYGTQRVISFLRQLVEHKGFYRASDQAWVSLERIQFVGACNPPTDPGRKPLSHRFLRHVPIIYVDYPGETSLKQIYGTFSRAMLRLMPALRGYAEPLTNAMVEFYLASQDRFTQDMQPHYVYSPREMTRWVRGICEAIRPLDSLPVEGLVRLWAHEALRLFQDRLVDDSERRWTNENIDLVGQKHFPGINQEEALQRPILYSNWLSKDYMPVNREELREYVHARLKVFYEEELDVPLVLFDEVLDHVLRIDRIFRQPQGHLLLIGVSGAGKTTLSRFVAWMNGLSIFQIKVHNKYTSEDFDEDLRCVLRRSGCKDEKIAFILDESNVLDSGFLERMNTLLANGEVPGLFEGDEYTTLMTQCKEGAQREGLMLDSSDELYKWFTQQVMRNLHVVFTMNPSTDGLKDRAATSPALFNRCVLNWFGDWSDSALFQVGKEFTTRVDLEKPNWHAPDFFPSVCP-LVPANPTHRDAVINSCVYVHQTLHQANARLAKRGGRTMAVTPRHYLDFIHHFVKLYNEKRSDLEEQQLHLNVGLNKIAETVEQVEEMQKSLAVKKQELQAKNEAANAKLKQMFQDQQEAEKKKIQSQEIQIRLADQTVKIEEKRKYVMADLAQVEPAVIDAQAAVKSIRKQQLVEVRTMANPPSVVKLALESICLLLGENATDWKSIRAVIMRENFINSIVSNFGTENITDDVREKMKSKYLSNPDYNFEKVNRASMACGPMVKWAIAQIEYADMLKRVEPLREELRSLEEQADVNLASAKETKDLVEQLERSIAAYKEEYAQLISQAQAIKTDLENVQAKVDRSIALLKSLNIERERWESTSETFKSQMSTIIGDVLLSAAFIAYGGYFDQHYRLNLFTTWSQHLQAASIQYRADIARTEYLSNPDERLRWQANALPTDDLCTENAIMLKRFNRYPLIIDPSGQATTFLLNEYAGKKITKTSFLDDSFRKNLESALRFGNPLLVQDVENYDPILNPVLNRELRRTGGRVLITLGDQDIDLSPSFVIFLSTRDPTVEFPPDICSRVTFVNFTVTRSSLQSQCLNQVLKAERPDIDEKRSDLLKLQGEFRLRLRQLEKSLLQALNDAKGKILDDDSVITTLETLKKEAYDINQKVDETDKVIAEIETVSQQYLPLSVACSNIYFTMDSLNQVHFLYQYSLKMFLDIFSTVLYNNPKLEGRTDHSERLGIVTRDLFQVCYERVARGMIHIDRLTFALLMCKIHLKGTSESN-LDAEFNFFLRSREGLL----ANPTPVEGLS--AEQIESVNRLALRLPIFRKLLEKVRSIPELGAWLQQSSPEQVVPQLWDE-----SKALSPIASSVHQLLLIQAFRPDRVIAAAHNVVNTVLGEDFMPNAEQELDFTSVVDKQLNCNTPALLCSVPGFDASGRVDDLAAEQNKQISSIAIGSAEGFNQAERAINMACKTGRWVLLKNVHLAPQWLVQLEKKMHSLQPHSGFRLFLTMEINPKVPVNLLRAGRIFVFEPPPGIRANLLRTFSTVPAARMMKTPSERARLYFLLAWFHAIVQERLRYVPLGWAKKYEFNESDLRVACDTLDTWIDTTAMGRTNLPPEKVPWDALVTLLSQSIYGGKIDNDFDQRLLTSFLKKLFTARSFEADFALVANVDGASGGLRHITMPDGTRRDHFLKWIENLTDRQTPSWLGLPNNAEKVLLTTRGTDLVSKLLKMQQ-LEDDDELAYSVEDQSEQSAVGRGEDGRPSWMKTLHNSATAWLELLPKNLQVLKRTVENIKDPLYRYFEREVTSGSRLLQTVILDLQDVVLICQGEKKQTNHHRSMLSELVRGIIPKGWKRYTVPAGCTVIQWITDFSNRVQQLQKVSQLVSQAGAKELQGFPVWLGGLLNPEAYITATRQCVAQANSWSLEELALDVTITDAGLKNDQKDCCFGVTGLKLQGAQCKNNELL-LASTIMMDLPVTILKWIKISSEPRI------SKLTLPVYLNSTRTELLFTVDLAVAAGQESHSFYERGVAV 4632
BLAST of Cytoplasmic dynein 1 heavy chain 1 vs. Ensembl Fly
Match: Dhc64C (gene:FBgn0261797 transcript:FBtr0273370) HSP 1 Score: 6091.53 bits (15802), Expect = 0.000e+0 Identity = 2929/4635 (63.19%), Postives = 3656/4635 (78.88%), Query Frame = 3 Query: 240 LSEPQNEECLTKFINDNQVTTLTIQQT--------KRXXXXXXXXXXXXKISNEVNFESNKSQTSIFIKNNQVIEADKTISSQLQVLSYCDGPPFETMHSLVCYGLLPYFXXXXXXXXXXXXXXXXXMVPSVEKKIAELEIGLLHLQQNIEIPEITLTPHPYVAHIIQEKLLQNKEARVSDFEDKFEDTQFLNQLQAGVNRWIKEIQKVTKLNRDPSTGTALQEISFWLNLEHSLDKIQEKRESLEVALTLAILKQAKRFHATTSFDTDTALSSAKIQVKDYNQLMKDFPINDLLSASQLDKISEALQQIFSHLKKVRATKYPVNRIIKLMEALSRDLTTQLMKVISNMHLMSMPYDEFEKIFTACQQVFSTWEDEYDKMQNLLRDIAKKKREEFTKFAWKMNATHKKLQTRLENIKKFRYQHEQLRQVIVRVLKPVTKVVPSVEAGVPKDQITDKGDKSSTFLP---ESADTSSIDEVNAAYEIVKVIDCLDFAKEENDEWDAAIKRYEERIDRVESRIASHLRDLLGQSKNANEMFRYFSRFNALFVRPHIRGAIGEYQTQLIQRVKDDIEALHNKFKVQYASSTACKMSKVRDLPPVSGSIIWVRQILRQLNAYMKRVEDVLGKDWAQHIEGQKLKADGESFKLKLNTSELFEEWSKKVAEKSLSVAGSIFNVESTRTVVTVRDREPQKITVLKLKVNFLPDVITLAKEVRNMRALGFRTPLSIVNKAHSANQLYPFAISLIESVRTYESTCSKIEEHKMQNISLLTAGLRKDVQLCIHEGVQITWESYRLDQYVQKLAELVFSFQEKVDDLVIVIKEIDFNVKALETCSYNKQTFEEILIRIQEAVDNMSLHQFSNLAQWVSNLDSLVEQRLIVRLEAGLLEWIKVLKGXXXXXXXXXXXXXXXVNSMAKHRLGGKPQIKKLIHELRITNQQMHLYPSIEVATQDILYQMSSWQNIILNLSRIVHSRYQVGLETESDNQKTYKKLLSSLPNSGESLENAYAAVHNILRDANEYVKTWTNYQSLWDLQGDQLFSLIADDNTVWMNVLEEIKSMRKHFDVAETQKEFGPLVIAFGKVQSKVSMKYDNWHKEVLTKFGQNMGKMMTTLYNEVQRARNELEQQSIDSGGTNESVNFITYTQNIKRKMNTWEKQAEACRAGQNILCRDRFQFPNDWLDSENIQGEWSAFKEIMRRKQETISSQVASLQMKITEEDKIVESKTTEVLGNWEKDKPIAGDLTPEEAVNIIQILEGKFNRLKEERENVQKAKEALELTEIGVKPISEEKVTNALSELHDLKNVWNELKSIWEKIRDMKETPWLSVQPRKLRQDIENLTAQLKELPNSFKQYASFEHVRTLLKMYMKVNASIVELKSEAIKERHWRMLMRKLNVSWSLNELQLGKVWDIDLVKNEEIIREVLAIAQGEKALEEYLRQITEVWKNYVLELTNYQSKSKIIKGWDDLFNKVKEHINNVTSMKASPYFKQFEEEATAWEDRLNKINALFDVWIDVQRRWIYLDGIFAGSADIKVLLPVESQRFQSVSTEFLGLMKKVQKSPLVTDVLNIANVQRQLERLADLLGKIQKSLGEYLERQRSSFPRFYFVGDEDLLEIIGNSXXXXXXXXXXXXMFAGVHSIILSEDEKVILGMMSKEGEELRFISPVSIIEHPRINDWLTAMEKEMRVSLAKYLNVAVKEISGWRTESNIDKDKFMVWLDKYQAQIVVLAAQITWSEAVEASLASGVS------LESTMTVVHSTLNMLADTVLYEQPPVRRRKLEHLIIEYVHQRDVLRALHNDGVSSNKNFDWMSQMRFYFDPKQTDPLHQLSIHVANAKFHYGFEYLGVCDRLVQTPLTDRCYLTMTQALEARLGGSPFGPAGTGKTESVKSLGNQLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLSAVSQQIQGIQEALRELMVSKKDSINVELLGKQVHVNPDMAIFITMNPGYAGRSNLPDNLKKLFRSLAMTQPDRQLIAQVMLYSQGFRTAEVLAGKVVPFFKLCDEQLSPQSHYDFGLRALKSVLVSAGNVKRDRIKQEKEKIVARGEE-INETAIAEQLPEQEILIQSVMETMVPKLIADDIPLLYSLLTDVFPGVEYRQAEMKRLREELRKVSENKFLVYSDEPNTAGYLWVEKVLQLYQITTIHHGLMMVGPSGSGKTMACRVLLQALENIDGIEGVAHIIDPKSISKDSLYGYMDPNTREWTDGLFTHILRRIIDSVRGESNKRQWIVFDGDVDPEWVENLNSVLDDNKLLTLPNGERLAIPPNVRIMFEVQDLKYATLATVSRCGMVWFSEEVLTTGMILTHFLNELKKVQVMEGEEDFSVNQGDTGADADSKISSSPIIQLQTQVSSILAPFFTEDGLIAKCLDYSTTLEHIMDFTRLRALTSLFSMIKQSIRNMIEYNQSHSDFPLNNEQIENYVAKSLISSVVWSMSGDSKLKVREQLSQYIKNISTVDLPTVGGIKNIIDFEVNIQGTWVAWSNKVPQIEVETHKITATDVVVPTMDTVRHEALLYTWLAEHRPVLLCGPPGSGKTMTLFSALRCLPDMEVVGLNFSSATTPELMLKTFDQYCEYRKTPNGIVLAPQQLNKWLIFFCDEINLPDMDKYGTQRVISFLRQMVEHHGFYRITDMQWVSFERIQFVGACNPPTDPGRKPLSHRFLRHVPVVYVDYPGETSLKQIYSTFNRAMLRMLPSLRGYADTLTNAMVEFFLKTQERFTHDMQPHYIYSPREMTRWVRGIHEALKPLESLSVEGLVRIWAHEALRLFQDRLVEEDERHWTDDNINEVALKHFPNINKEEALKRPILYSNWLSKDYSAVTQEELRDYVKARLKVFYEEELDVPLVLFNQVLDHVLRIDRVFRQPQGHLLLIGVSGAGKTTLSRFVSWINGLSVFQVKVHNKYTAEDFDEDLRNVLRRSGCKGEKITFIMDESNVMDSSFLERMNTLLANGEVPGLFEGDELTTLMTQCKEGAIREGLMIDSQEELYKWFTQQICRNLHVVFTMNPSADGLKDKASTSPALFNRCVLNWFGDWSLEAYFQVGKEFTNRLDLERTDYKVPDTLPCIAEGLLPQNPIYRDVVVNALVFVHQTMHQANVRVQKRGGRTAAITPRHYLDLIAHYMKLSAEKRADLEEQQLHLNNGLKKIEQTVDQVEVMQRSLTKKRQELENMNEAANAKLKQMVQDQQEAEQKKTTGQALKEELAKQEQFVNEKQKTVKQELDQVEPTVNEAKQAVQNIRKKDIQEIKAMKNPPNAVKMAVESICLLLGEKTTDWQSILKVIIKDTFVTSILNFNTDDVSDNTRETMKKKYLSNPDYNFEKVNKASNACGPMVKWVLAQISYADILKRVEPLRNELTELSDAAEQNRKKSQETEDLIAQLEKSIAKYTEEYATLISQAQTIKSDLASVESKVGRSVALLGSLSSERTRWDSGSETFKAQMATINGDCLLSSAFMAYGGYFDQHMRTSLFNTWCHHLSEADILFRSDLARVEYLSNPDDRLRWQANSLPADDLCVENAIILRRYNRYPLIIDPSGQATTFLLNEYKEKKITKTSFLDDSFRKTLESALRFGTPLLVQDVESYDPILNPVLNREVRRTGGRTLITLGDQDIDLSPTFTIFLSTRDPSVEFAPDICSRVTFVNFTVTRSSLQNQCLNAVLKIERPDIDQKRSDLLKAQGEFQLKLRHLEKDLLQSLNEAQGNLLENDKIIARLETLKREAADVAKKVEETDVVMQEVESVSTEYVPLAQSCSNIYFTLEAMNQIHFLYQYSLQLMLDIFSSVLINNPELTNVKAASDRLKIITKNLFQVTYNRLARGMLHEDQITFATILARIFLKGSTPIGFLENEFQHFLRSQEATITSSDSNKQDNLGLTLHQDQIDSVKRLK-KLKVFAKIEEKVKSTKDIKNWTLTVTPESNVPELWVDDNNYNDEKLSKIAKGMYNLLIIQAIRPDRLLASTQKFIASVLGDTFTESVRGTLDLASIVEVEVTACVPILLCAVQGYDPSGRVEDLASEQGKQLTGIAIGSAEGFSQAEKAINSAAKTGKWVMLKNVHLATSWLVSLEKKIHSLQAHPNFRLFLTMEITPKLPVNLLRAGRVLVFEPPPGIKANLLRTLSSINNQRMSKEPVERSRLYFLLAWLNAIVQERLRYVPLGYSKKYEFGESDFKCALDTIDTWVDGAAMGRTNLPPEKIPWVALQTLLGSCIYGGKIDNAFDQRLLNSFLGYLFTEKCFDHNFALVSDADDGS----NIAFPESTKHTDILQWVHKLPDLQTPSWLGLPNSAEKVLLTNLGQSLIGNILKMQQSLEDDEELVVGQSKTKRTIEVG---DGRPAWMRQLYQSTQTWLQILPKSVTPLQRTIENIKDPMYRCFEREVNSGCNLLASVRKDLEDVAEVCKGAKKPTNHHRSMMADLAKGIIPKMWIRYAIPPGLTVIQWIQDFADRIKQLLHISDTAAKSGVIALRSIQVWLGGLFMAEAYITATRQSVAQNNKWALEELFLDVELGEG--KVDSNTCV--ITGLRLMGSEIVDPRTLKLSTLIYKDIDICRLKWIRVEKSQQLEGSSAKDKVCLPIYLNAARSTVLFT--LYFSTTDSSYDFYKRGVAI 14048 L +P N++ + KF++D QV L +Q+ + E E + + ++ISN+V+F +++ + IK V+EADK+I SQL+++++ DG P+ET+H+ + L PYFKSY+K+ G+ M PSVEKK+AELE+GLLHLQQNI+IPEITLT H V ++I++ +N++A+V+DF DK ED+ FLN LQ GVNRWI EI+KVTKLNRDP +GTALQEISFWLNLE +L +IQEKRES EVALTL ILK KRFHAT SFDTDT L A V DYN LMKDFPINDLLSA++L+KI A+QQIF+HL+KVR TKYP+ R +KL+EA+SRDL+ QL+KV+ LM +P+DEFE++ C ++FS W+DEYDK+Q LLRDI KKKR+E K W+++ HKKLQTR+E+++KFR QHEQLR VI+RVL+P K + D G+ T P ++AD ++I+EVN AYE VK +DCLD KE ++ W+AA+KRYEE+IDRVE+RI +HLRD LG +KNANEMFR FSRFNALFVRPHIRGAI EYQTQLIQRVKDDIEALH KFKVQY S +C++S VRDLPPV+GSIIW RQI QL Y+KRVEDVLGK W HIEGQKLKADG+SF+ KL+ S++F EW++KV E++ G IF +ESTR+ + + VL+L+VNFLP++ITLAKEVRN++ LGFR PL+IVNKAH ANQ+YP+AISLIESVRTYE T KIE+ +I L AGLRKDV + EG+ + WESY+LD YV +L+E V FQEKVDDL++V +++D +V++LETC Y+ TF EIL +IQ AVD++SL Q+SNL+ WV+ LD VE++L +RL+AG+ W + L G +E + + H+LGG PQI+ +HE+RITNQQM+LYPSIE A I+ Q +WQ I+ + R+ +RYQVGLE +TY+ LL+ LP G+ LENAY A+ + + YV W YQSLWDLQ D L+ + +D +W+ L +IK R FD ++T++ +GP++I + KVQ+KV++KYD+WHKE L KFG +G MT+ +++V ++R +LE QSI++ T+++V+FITY Q++K+ M W+KQ E R Q IL R RFQFPN WL +NI+GEWSAF EI++RK I +QVASLQ KI EDK VE++T + L +WEK KP G + P++A+ +QI E K++RLKEER+NV KAKEALEL E V S E++ AL EL DL+ VW+EL +W +I + +E PWLSVQPRKLRQ +E + AQLKELP + Y S+E+V+ L++ Y+KVN IVELKS+A+KERHW+ L ++L V+W L++L LG+VWD++L KNE I+++++ +AQGE ALEE+L+Q+ E W+NY L+L NYQ+K +II+GWDDLFNKVKEHIN+V +MK SPY+K FEEEA WE++LN+INALFDVWIDVQRRW+YL+GIF+GSADIK LLPVE+ RFQS+S+EFLGLMKKV KSP V DVLNI VQR LERLADLLGKIQK+LGEYLER+R+SFPRFYFVGDEDLLEIIGNSK++ +LQKHFKKMFAGV +I+L+E+ VILG+ S+EGEE+ F++PVS +EHP+IN+WL+ +EK+MR +LA L AV++I +R + ID +M W DKYQAQIVVLAAQI WSE VE++L ++ + V STLN+LAD+VL EQPP+RRRKLEHLI E+VH+R V R L N+GV+S K+F W+ +MRFYFDP+QT+ L QL+IH+ANA+F YGFEYLGV DRLVQTPLTDRCYLTMTQALE+RLGGSPFGPAGTGKTESVK+LGNQLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLSA SQQIQ IQEAL+ M S K+SI VEL+GKQV V+PDMAIFITMNPGYAGRSNLPDNLKKLFRSLAMT PDRQLIA+VML+SQGFR+AE LA K+VPFFKLCDEQLS QSHYDFGLRALKSVL+SAGNVKRDRI + KE++ RG+E I+E ++AE LPEQEILIQSV ETMVPKL+A+DIPLL+SLL+DVFP V Y +AEMK L+EE+RKV + +LV E + G W+EKVLQLYQI+ ++HGLMMVGPSGSGK+ A + LL+ALE +G+EGVAH+IDPK+ISK++LYG +DPNTREWTDGLFTHILR+IID+VRGE NKRQWI+FDGDVDPEWVENLNSVLDDNKLLTLPNGERL++PPNVR+MFEVQDLK+ATLATVSRCGMVWFSE+VL+T MI ++L+ L+ + + +G+EDF G D + SP +Q+Q ++ +L PFF+ DG++ + L+Y+ EHIMDFTRLRAL+SLFSM+ Q+ RN++ +N H DFP + +Q+E+Y+ K+L+ SV+WS +GD+KLKVR L ++++++TV LP G IID+EVN+ G WV WSNKVP IEVETHK+ + D+VVPT+DTVRHE+LLYTWLAEH+P++LCGPPGSGKTMTLFSALR LPDMEVVGLNFSSATTPEL+LKTFD YCEYRKTPNG+VL+P Q+ KWL+ FCDEINLPDMD YGTQRVISFLRQ+VEH GFYR +D WVS ERIQFVGACNPPTDPGRKPLSHRFLRHVP++YVDYPGETSLKQIY TF+RAMLR++P+LRGYA+ LTNAMVEF+L +Q+RFT DMQPHY+YSPREMTRWVRGI EA++PL+SL VEGLVR+WAHEALRLFQDRLV++ ER WT++NI+ V KHFP IN+EEAL+RPILYSNWLSKDY V +EELR+YV ARLKVFYEEELDVPLVLF++VLDHVLRIDR+FRQPQGHLLLIGVSGAGKTTLSRFV+W+NGLS+FQ+KVHNKYT+EDFDEDLR VLRRSGCK EKI FI+DESNV+DS FLERMNTLLANGEVPGLFEGDE TTLMTQCKEGA REGLM+DS +ELYKWFTQQ+ RNLHVVFTMNPS DGLKD+A+TSPALFNRCVLNWFGDWS A FQVGKEFT R+DLE+ ++ PD P + L+P NP +RD V+N+ V+VHQT+HQAN R+ KRGGRT A+TPRHYLD I H++KL EKR+DLEEQQLHLN GL KI +TV+QVE MQ+SL K+QEL+ NEAANAKLKQM QDQQEAE+KK Q ++ LA Q + EK+K V +L QVEP V +A+ AV +I+KK + E+++M NPP VK+A+ES+C LL E TDW++I +++KD+F++SI+N TD ++D+ RE MK KYLSNPDYNFEKVN+AS ACGPMVKW +AQI YAD+LKRVEPLR EL L + A+ N ++ET+DL+ QLE+SIA Y EEYA LISQAQ IK+DL +V++KV RS+ALL SL+ ER RW+S SETFK+QM+TI GD LLS+AF+AYGGYFDQH R +LF TW HL A I +R+D+AR EYLSNPD+RLRWQAN+LP DDLC ENAI+L+R+NRYPLIIDPSGQATTFLLNEY KKITKTSFLDDSFRK LESALRFG PLLVQDVE+YDPILNPVLNRE+RRTGGR LITLGDQDIDLSP+F IFLSTRDP+VEF PDICSRVTFVNFTVTRSSLQ+QCLN VLK ERPDID+KRSDLLK QGEF+L+LR LEK LLQ+LN+A+G +L++D +I LETLK+EA D+ +KV+ETD V+ E+E+VS +Y+PL+ +CSNIYFT++++NQ+HFLYQYSL++ LDIFS+VL NNP+L S+RL I+T++LFQV Y R+ARGM+H D++TFA ++ +I LKG++ L+ EF FLRS+E + +N GL+ +QI+SV RL +L +F K+ EKV+S ++ W +PE VP+LW + + LS IA ++ LL+IQA RPDR++A+ + +VLG+ F + LD S+V+ ++ P LLC+V G+D SGRV+DLA+EQ KQ++ IAIGSAEGF+QAE+AIN A KTG+WV+LKNVHLA WLV LEKK+HSLQ H FRLFLTMEI PK+PVNLLRAGR+ VFEPPPGI+ANLLRT S++ RM K P ER+RLYFLLAW +AIVQERLRYVPLG++KKYEF ESD + A DT+DTW+D AMGRTNLPPEK+PW AL TLL IYGGKIDN FDQRLL SFL LFT + F+ +FALV++ D S +I P+ T+ L+W+ L D QTPSWLGLPN+AEKVLLT G L+ +LKMQQ LEDD+EL VG DGRP+WM+ L+ S WL++LPK++ L+RT+ENIKDP+YR FEREV SG LL +V DL+DV +C+G KK TNHHRSM+++L +GIIPK W RY +P G TVIQWI DF++R++QL +S +++G L+ VWLGGL EAYITATRQ VAQ N W+LEEL LDV + + K D C +TGL+L G++ + L L++ I D+ + LKWI++ ++ K+ LP+YLN+ R+ +LFT L + S+ FY+RGVA+ Sbjct: 52 LDDPVNQDTIRKFLSDPQVQALYVQRNCIKEDDSEQPAEGEDEKEQVTYQISNDVHFTNSRMASLACIKRGLVVEADKSIHSQLRLINFSDGSPYETLHAFISKSLAPYFKSYVKESGRADRDGDK-MAPSVEKKLAELEMGLLHLQQNIDIPEITLTAHQTVNNVIRKCAEENRKAKVADFGDKVEDSSFLNLLQNGVNRWIAEIKKVTKLNRDPGSGTALQEISFWLNLERALYRIQEKRESPEVALTLDILKHGKRFHATVSFDTDTGLKQALATVADYNPLMKDFPINDLLSATELEKIRPAVQQIFAHLRKVRNTKYPIQRCLKLIEAISRDLSQQLLKVLGTRRLMHIPFDEFERVMNQCFEIFSCWDDEYDKLQGLLRDIVKKKRDEHLKMVWRVSPAHKKLQTRMEHMRKFRRQHEQLRTVILRVLRPT------------KPAVGDDGNVVETKQPYSLDAADANAIEEVNLAYENVKEVDCLDITKEGSEAWEAAVKRYEEKIDRVETRITAHLRDQLGTAKNANEMFRIFSRFNALFVRPHIRGAIREYQTQLIQRVKDDIEALHEKFKVQYPQSKSCRLSSVRDLPPVAGSIIWARQIDNQLTMYLKRVEDVLGKGWETHIEGQKLKADGDSFRAKLSISDVFHEWARKVQERNFGSTGRIFTIESTRSRIG-------RGNVLRLRVNFLPEIITLAKEVRNIKNLGFRVPLTIVNKAHQANQIYPYAISLIESVRTYERTLEKIEDRA--SIVPLVAGLRKDVLNLVSEGIGLIWESYKLDPYVIRLSECVTQFQEKVDDLLVVEEQLDVDVRSLETCPYSAATFVEILSKIQHAVDDLSLRQYSNLSVWVTRLDEEVEKKLALRLQAGIQAWTEALTGNKKEVDTSMDTD---APAQPTHKLGGDPQIQNAVHEIRITNQQMYLYPSIEEARFQIMQQFFAWQAIVTSQVRLQSTRYQVGLEKHV--SQTYRNLLTKLP-EGKILENAYGAIEQKVSEVRNYVDEWLRYQSLWDLQADMLYGRLGEDVNLWIKCLNDIKQSRTTFDTSDTRRAYGPIIIDYAKVQAKVTLKYDSWHKEALGKFGTLLGTEMTSFHSKVSKSRTDLEMQSIEAASTSDAVSFITYVQSLKKDMIAWDKQVEVFREAQRILERQRFQFPNTWLHVDNIEGEWSAFNEIIKRKDTAIQTQVASLQAKIVAEDKAVETRTVDFLNDWEKTKPTGGKIRPDDALQQLQIFESKYSRLKEERDNVVKAKEALELQESAVPNNSAERMNVALEELQDLRGVWSELSKVWTQIDETREKPWLSVQPRKLRQQLEAMMAQLKELPARLRMYESYEYVKKLIQSYIKVNMLIVELKSDALKERHWKQLTKQLRVNWVLSDLSLGQVWDVNLQKNEGIVKDIILVAQGEMALEEFLKQVRESWQNYELDLINYQNKCRIIRGWDDLFNKVKEHINSVAAMKLSPYYKVFEEEALTWEEKLNRINALFDVWIDVQRRWVYLEGIFSGSADIKTLLPVETSRFQSISSEFLGLMKKVTKSPKVMDVLNIPAVQRSLERLADLLGKIQKALGEYLERERTSFPRFYFVGDEDLLEIIGNSKNIARLQKHFKKMFAGVAAILLNEENNVILGISSREGEEVHFMNPVSTVEHPKINEWLSLVEKQMRFTLASLLAQAVQDIKQFR-DGKIDPQAYMEWCDKYQAQIVVLAAQILWSEDVESALQQASENNQSKPMQRVLGNVESTLNVLADSVLQEQPPLRRRKLEHLINEFVHKRTVTRRLLNNGVTSPKSFQWLCEMRFYFDPRQTEVLQQLTIHMANARFFYGFEYLGVQDRLVQTPLTDRCYLTMTQALESRLGGSPFGPAGTGKTESVKALGNQLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLSACSQQIQTIQEALKYEMDSNKESITVELVGKQVRVSPDMAIFITMNPGYAGRSNLPDNLKKLFRSLAMTTPDRQLIAEVMLFSQGFRSAEKLACKIVPFFKLCDEQLSNQSHYDFGLRALKSVLISAGNVKRDRIMKIKEQMKQRGDENIDEASVAENLPEQEILIQSVCETMVPKLVAEDIPLLFSLLSDVFPNVGYTRAEMKGLKEEIRKVCQEDYLV-CGEGDEQGAAWMEKVLQLYQISNLNHGLMMVGPSGSGKSTAWKTLLKALERFEGVEGVAHVIDPKAISKEALYGVLDPNTREWTDGLFTHILRKIIDNVRGEINKRQWIIFDGDVDPEWVENLNSVLDDNKLLTLPNGERLSLPPNVRVMFEVQDLKFATLATVSRCGMVWFSEDVLSTEMIFENYLSRLRSIPLEDGDEDFV---GVIKPAKDKEEEVSPSLQVQRDIALLLLPFFSADGIVVRTLEYAMDQEHIMDFTRLRALSSLFSMLNQAARNVLTFNAQHPDFPCSADQLEHYIPKALVYSVLWSFAGDAKLKVRIDLGDFVRSVTTVPLPGAAGAP-IIDYEVNMSGDWVPWSNKVPVIEVETHKVASPDIVVPTLDTVRHESLLYTWLAEHKPLVLCGPPGSGKTMTLFSALRALPDMEVVGLNFSSATTPELLLKTFDHYCEYRKTPNGVVLSPVQIGKWLVLFCDEINLPDMDSYGTQRVISFLRQLVEHKGFYRASDQAWVSLERIQFVGACNPPTDPGRKPLSHRFLRHVPIIYVDYPGETSLKQIYGTFSRAMLRLMPALRGYAEPLTNAMVEFYLASQDRFTQDMQPHYVYSPREMTRWVRGICEAIRPLDSLPVEGLVRLWAHEALRLFQDRLVDDSERRWTNENIDLVGQKHFPGINQEEALQRPILYSNWLSKDYMPVNREELREYVHARLKVFYEEELDVPLVLFDEVLDHVLRIDRIFRQPQGHLLLIGVSGAGKTTLSRFVAWMNGLSIFQIKVHNKYTSEDFDEDLRCVLRRSGCKDEKIAFILDESNVLDSGFLERMNTLLANGEVPGLFEGDEYTTLMTQCKEGAQREGLMLDSSDELYKWFTQQVMRNLHVVFTMNPSTDGLKDRAATSPALFNRCVLNWFGDWSDSALFQVGKEFTTRVDLEKPNWHAPDFFPSVCP-LVPANPTHRDAVINSCVYVHQTLHQANARLAKRGGRTMAVTPRHYLDFIHHFVKLYNEKRSDLEEQQLHLNVGLNKIAETVEQVEEMQKSLAVKKQELQAKNEAANAKLKQMFQDQQEAEKKKIQSQEIQIRLADQTVKIEEKRKYVMADLAQVEPAVIDAQAAVSSIKKKHLAEVRSMANPPAVVKLALESVCELLNESATDWKAIRGILVKDSFISSIVNLETDKITDDVREKMKSKYLSNPDYNFEKVNRASMACGPMVKWAIAQIEYADMLKRVEPLREELRSLEEQADVNLASAKETKDLVEQLERSIAAYKEEYAQLISQAQAIKTDLENVQAKVDRSIALLKSLNIERERWESTSETFKSQMSTIIGDVLLSAAFIAYGGYFDQHYRLNLFTTWSQHLQAASIQYRADIARTEYLSNPDERLRWQANALPTDDLCTENAIMLKRFNRYPLIIDPSGQATTFLLNEYAGKKITKTSFLDDSFRKNLESALRFGNPLLVQDVENYDPILNPVLNRELRRTGGRVLITLGDQDIDLSPSFVIFLSTRDPTVEFPPDICSRVTFVNFTVTRSSLQSQCLNQVLKAERPDIDEKRSDLLKLQGEFRLRLRQLEKSLLQALNDAKGKILDDDSVITTLETLKKEAYDINQKVDETDKVIAEIETVSQQYLPLSVACSNIYFTMDSLNQVHFLYQYSLKMFLDIFSTVLYNNPKLEGRTDHSERLGIVTRDLFQVCYERVARGMIHIDRLTFALLMCKIHLKGTSESN-LDAEFNFFLRSREGLL----ANPTPVEGLS--AEQIESVNRLALRLPIFRKLLEKVRSIPELGAWLQQSSPEQVVPQLWDE-----SKALSPIASSVHQLLLIQAFRPDRVIAAAHNVVNTVLGEDFMPNAEQELDFTSVVDKQLNCNTPALLCSVPGFDASGRVDDLAAEQNKQISSIAIGSAEGFNQAERAINMACKTGRWVLLKNVHLAPQWLVQLEKKMHSLQPHSGFRLFLTMEINPKVPVNLLRAGRIFVFEPPPGIRANLLRTFSTVPAARMMKTPSERARLYFLLAWFHAIVQERLRYVPLGWAKKYEFNESDLRVACDTLDTWIDTTAMGRTNLPPEKVPWDALVTLLSQSIYGGKIDNDFDQRLLTSFLKKLFTARSFEADFALVANVDGASGGLRHITMPDGTRRDHFLKWIENLTDRQTPSWLGLPNNAEKVLLTTRGTDLVSKLLKMQQ-LEDDDELAYSVEDQSEQSAVGRGEDGRPSWMKTLHNSATAWLELLPKNLQVLKRTVENIKDPLYRYFEREVTSGSRLLQTVILDLQDVVLICQGEKKQTNHHRSMLSELVRGIIPKGWKRYTVPAGCTVIQWITDFSNRVQQLQKVSQLVSQAGAKELQGFPVWLGGLLNPEAYITATRQCVAQANSWSLEELALDVTITDAGLKNDQKDCCFGVTGLKLQGAQCKNNELL-LASTIMMDLPVTILKWIKISSEPRI------SKLTLPVYLNSTRTELLFTVDLAVAAGQESHSFYERGVAV 4631
BLAST of Cytoplasmic dynein 1 heavy chain 1 vs. Ensembl Fly
Match: Dhc64C (gene:FBgn0261797 transcript:FBtr0332748) HSP 1 Score: 6091.15 bits (15801), Expect = 0.000e+0 Identity = 2935/4644 (63.20%), Postives = 3660/4644 (78.81%), Query Frame = 3 Query: 240 LSEPQNEECLTKFINDNQVTTLTIQQT--------KRXXXXXXXXXXXXKISNEVNFESNKSQTSIFIKNNQVIEADKTISSQLQVLSYCDGPPFETMHSLVCYGLLPYFXXXXXXXXXXXXXXXXXMVPSVEKKIAELEIGLLHLQQNIEIPEITLTPHPYVAHIIQEKLLQNKEARVSDFEDKFEDTQFLNQLQAGVNRWIKEIQKVTKLNRDPSTGTALQEISFWLNLEHSLDKIQEKRESLEVALTLAILKQAKRFHATTSFDTDTALSSAKIQVKDYNQLMKDFPINDLLSASQLDKISEALQQIFSHLKKVRATKYPVNRIIKLMEALSRDLTTQLMKVISNMHLMSMPYDEFEKIFTACQQVFSTWEDEYDKMQNLLRDIAKKKREEFTKFAWKMNATHKKLQTRLENIKKFRYQHEQLRQVIVRVLKPVTKVVPSVEAGVPKDQITDKGDKSSTFLP---ESADTSSIDEVNAAYEIVKVIDCLDFAKEENDEWDAAIKRYEERIDRVESRIASHLRDLLGQSKNANEMFRYFSRFNALFVRPHIRGAIGEYQTQLIQRVKDDIEALHNKFKVQYASSTACKMSKVRDLPPVSGSIIWVRQILRQLNAYMKRVEDVLGKDWAQHIEGQKLKADGESFKLKLNTSELFEEWSKKVAEKSLSVAGSIFNVESTRTVVTVRDREPQKITVLKLKVNFLPDVITLAKEVRNMRALGFRTPLSIVNKAHSANQLYPFAISLIESVRTYESTCSKIEEHKMQNISLLTAGLRKDVQLCIHEGVQITWESYRLDQYVQKLAELVFSFQEKVDDLVIVIKEIDFNVKALETCSYNKQTFEEILIRIQEAVDNMSLHQFSNLAQWVSNLDSLVEQRLIVRLEAGLLEWIKVLKGXXXXXXXXXXXXXXXVNSMAKHRLGGKPQIKKLIHELRITNQQMHLYPSIEVATQDILYQMSSWQNIILNLSRIVHSRYQVGLETESDNQKTYKKLLSSLPNSGESLENAYAAVHNILRDANEYVKTWTNYQSLWDLQGDQLFSLIADDNTVWMNVLEEIKSMRKHFDVAETQKEFGPLVIAFGKVQSKVSMKYDNWHKEVLTKFGQNMGKMMTTLYNEVQRARNELEQQSIDSGGTNESVNFITYTQNIKRKMNTWEKQAEACRAGQNILCRDRFQFPNDWLDSENIQGEWSAFKEIMRRKQETISSQVASLQMKITEEDKIVESKTTEVLGNWEKDKPIAGDLTPEEAVNIIQILEGKFNRLKEERENVQKAKEALELTEIGVKPISEEKVTNALSELHDLKNVWNELKSIWEKIRDMKETPWLSVQPRKLRQDIENLTAQLKELPNSFKQYASFEHVRTLLKMYMKVNASIVELKSEAIKERHWRMLMRKLNVSWSLNELQLGKVWDIDLVKNEEIIREVLAIAQGEKALEEYLRQITEVWKNYVLELTNYQSKSKIIKGWDDLFNKVKEHINNVTSMKASPYFKQFEEEATAWEDRLNKINALFDVWIDVQRRWIYLDGIFAGSADIKVLLPVESQRFQSVSTEFLGLMKKVQKSPLVTDVLNIANVQRQLERLADLLGKIQKSLGEYLERQRSSFPRFYFVGDEDLLEIIGNSXXXXXXXXXXXXMFAGVHSIILSEDEKVILGMMSKEGEELRFISPVSIIEHPRINDWLTAMEKEMRVSLAKYLNVAVKEISGWRTESNIDKDKFMVWLDKYQAQIVVLAAQITWSEAVEASLASGVS------LESTMTVVHSTLNMLADTVLYEQPPVRRRKLEHLIIEYVHQRDVLRALHNDGVSSNKNFDWMSQMRFYFDPKQTDPLHQLSIHVANAKFHYGFEYLGVCDRLVQTPLTDRCYLTMTQALEARLGGSPFGPAGTGKTESVKSLGNQLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLSAVSQQIQGIQEALRELMVSKKDSINVELLGKQVHVNPDMAIFITMNPGYAGRSNLPDNLKKLFRSLAMTQPDRQLIAQVMLYSQGFRTAEVLAGKVVPFFKLCDEQLSPQSHYDFGLRALKSVLVSAGNVKRDRIKQEKEKIVARGEE-INETAIAEQLPEQEILIQSVMETMVPKLIADDIPLLYSLLTDVFPGVEYRQAEMKRLREELRKVSENKFLVYS--DEPNTA------GYLWVEKVLQLYQITTIHHGLMMVGPSGSGKTMACRVLLQALENIDGIEGVAHIIDPKSISKDSLYGYMDPNTREWTDGLFTHILRRIIDSVRGESNKRQWIVFDGDVDPEWVENLNSVLDDNKLLTLPNGERLAIPPNVRIMFEVQDLKYATLATVSRCGMVWFSEEVLTTGMILTHFLNELKKVQVMEGEEDFSVNQGDTGADADSKISSSPIIQLQTQVSSILAPFFTEDGLIAKCLDYSTTLEHIMDFTRLRALTSLFSMIKQSIRNMIEYNQSHSDFPLNNEQIENYVAKSLISSVVWSMSGDSKLKVREQLSQYIKNISTVDLPTVGGIKNIIDFEVNIQGTWVAWSNKVPQIEVETHKITATDVVVPTMDTVRHEALLYTWLAEHRPVLLCGPPGSGKTMTLFSALRCLPDMEVVGLNFSSATTPELMLKTFDQYCEYRKTPNGIVLAPQQLNKWLIFFCDEINLPDMDKYGTQRVISFLRQMVEHHGFYRITDMQWVSFERIQFVGACNPPTDPGRKPLSHRFLRHVPVVYVDYPGETSLKQIYSTFNRAMLRMLPSLRGYADTLTNAMVEFFLKTQERFTHDMQPHYIYSPREMTRWVRGIHEALKPLESLSVEGLVRIWAHEALRLFQDRLVEEDERHWTDDNINEVALKHFPNINKEEALKRPILYSNWLSKDYSAVTQEELRDYVKARLKVFYEEELDVPLVLFNQVLDHVLRIDRVFRQPQGHLLLIGVSGAGKTTLSRFVSWINGLSVFQVKVHNKYTAEDFDEDLRNVLRRSGCKGEKITFIMDESNVMDSSFLERMNTLLANGEVPGLFEGDELTTLMTQCKEGAIREGLMIDSQEELYKWFTQQICRNLHVVFTMNPSADGLKDKASTSPALFNRCVLNWFGDWSLEAYFQVGKEFTNRLDLERTDYKVPDTLPCIAEGLLPQNPIYRDVVVNALVFVHQTMHQANVRVQKRGGRTAAITPRHYLDLIAHYMKLSAEKRADLEEQQLHLNNGLKKIEQTVDQVEVMQRSLTKKRQELENMNEAANAKLKQMVQDQQEAEQKKTTGQALKEELAKQEQFVNEKQKTVKQELDQVEPTVNEAKQAVQNIRKKDIQEIKAMKNPPNAVKMAVESICLLLGEKTTDWQSILKVIIKDTFVTSIL-NFNTDDVSDNTRETMKKKYLSNPDYNFEKVNKASNACGPMVKWVLAQISYADILKRVEPLRNELTELSDAAEQNRKKSQETEDLIAQLEKSIAKYTEEYATLISQAQTIKSDLASVESKVGRSVALLGSLSSERTRWDSGSETFKAQMATINGDCLLSSAFMAYGGYFDQHMRTSLFNTWCHHLSEADILFRSDLARVEYLSNPDDRLRWQANSLPADDLCVENAIILRRYNRYPLIIDPSGQATTFLLNEYKEKKITKTSFLDDSFRKTLESALRFGTPLLVQDVESYDPILNPVLNREVRRTGGRTLITLGDQDIDLSPTFTIFLSTRDPSVEFAPDICSRVTFVNFTVTRSSLQNQCLNAVLKIERPDIDQKRSDLLKAQGEFQLKLRHLEKDLLQSLNEAQGNLLENDKIIARLETLKREAADVAKKVEETDVVMQEVESVSTEYVPLAQSCSNIYFTLEAMNQIHFLYQYSLQLMLDIFSSVLINNPELTNVKAASDRLKIITKNLFQVTYNRLARGMLHEDQITFATILARIFLKGSTPIGFLENEFQHFLRSQEATITSSDSNKQDNLGLTLHQDQIDSVKRLK-KLKVFAKIEEKVKSTKDIKNWTLTVTPESNVPELWVDDNNYNDEKLSKIAKGMYNLLIIQAIRPDRLLASTQKFIASVLGDTFTESVRGTLDLASIVEVEVTACVPILLCAVQGYDPSGRVEDLASEQGKQLTGIAIGSAEGFSQAEKAINSAAKTGKWVMLKNVHLATSWLVSLEKKIHSLQAHPNFRLFLTMEITPKLPVNLLRAGRVLVFEPPPGIKANLLRTLSSINNQRMSKEPVERSRLYFLLAWLNAIVQERLRYVPLGYSKKYEFGESDFKCALDTIDTWVDGAAMGRTNLPPEKIPWVALQTLLGSCIYGGKIDNAFDQRLLNSFLGYLFTEKCFDHNFALVSDADDGS----NIAFPESTKHTDILQWVHKLPDLQTPSWLGLPNSAEKVLLTNLGQSLIGNILKMQQSLEDDEELVVGQSKTKRTIEVG---DGRPAWMRQLYQSTQTWLQILPKSVTPLQRTIENIKDPMYRCFEREVNSGCNLLASVRKDLEDVAEVCKGAKKPTNHHRSMMADLAKGIIPKMWIRYAIPPGLTVIQWIQDFADRIKQLLHISDTAAKSGVIALRSIQVWLGGLFMAEAYITATRQSVAQNNKWALEELFLDVELGEG--KVDSNTCV--ITGLRLMGSEIVDPRTLKLSTLIYKDIDICRLKWIRVEKSQQLEGSSAKDKVCLPIYLNAARSTVLFT--LYFSTTDSSYDFYKRGVAI 14048 L +P N++ + KF++D QV L +Q+ + E E + + ++ISN+V+F +++ + IK V+EADK+I SQL+++++ DG P+ET+H+ + L PYFKSY+K+ G+ M PSVEKK+AELE+GLLHLQQNI+IPEITLT H V ++I++ +N++A+V+DF DK ED+ FLN LQ GVNRWI EI+KVTKLNRDP +GTALQEISFWLNLE +L +IQEKRES EVALTL ILK KRFHAT SFDTDT L A V DYN LMKDFPINDLLSA++L+KI A+QQIF+HL+KVR TKYP+ R +KL+EA+SRDL+ QL+KV+ LM +P+DEFE++ C ++FS W+DEYDK+Q LLRDI KKKR+E K W+++ HKKLQTR+E+++KFR QHEQLR VI+RVL+P K + D G+ T P ++AD ++I+EVN AYE VK +DCLD KE ++ W+AA+KRYEE+IDRVE+RI +HLRD LG +KNANEMFR FSRFNALFVRPHIRGAI EYQTQLIQRVKDDIEALH KFKVQY S +C++S VRDLPPV+GSIIW RQI QL Y+KRVEDVLGK W HIEGQKLKADG+SF+ KL+ S++F EW++KV E++ G IF +ESTR+ + + VL+L+VNFLP++ITLAKEVRN++ LGFR PL+IVNKAH ANQ+YP+AISLIESVRTYE T KIE+ +I L AGLRKDV + EG+ + WESY+LD YV +L+E V FQEKVDDL++V +++D +V++LETC Y+ TF EIL +IQ AVD++SL Q+SNL+ WV+ LD VE++L +RL+AG+ W + L G +E + + H+LGG PQI+ +HE+RITNQQM+LYPSIE A I+ Q +WQ I+ + R+ +RYQVGLE +TY+ LL+ LP G+ LENAY A+ + + YV W YQSLWDLQ D L+ + +D +W+ L +IK R FD ++T++ +GP++I + KVQ+KV++KYD+WHKE L KFG +G MT+ +++V ++R +LE QSI++ T+++V+FITY Q++K+ M W+KQ E R Q IL R RFQFPN WL +NI+GEWSAF EI++RK I +QVASLQ KI EDK VE++T + L +WEK KP G + P++A+ +QI E K++RLKEER+NV KAKEALEL E V S E++ AL EL DL+ VW+EL +W +I + +E PWLSVQPRKLRQ +E + AQLKELP + Y S+E+V+ L++ Y+KVN IVELKS+A+KERHW+ L ++L V+W L++L LG+VWD++L KNE I+++++ +AQGE ALEE+L+Q+ E W+NY L+L NYQ+K +II+GWDDLFNKVKEHIN+V +MK SPY+K FEEEA WE++LN+INALFDVWIDVQRRW+YL+GIF+GSADIK LLPVE+ RFQS+S+EFLGLMKKV KSP V DVLNI VQR LERLADLLGKIQK+LGEYLER+R+SFPRFYFVGDEDLLEIIGNSK++ +LQKHFKKMFAGV +I+L+E+ VILG+ S+EGEE+ F++PVS +EHP+IN+WL+ +EK+MR +LA L AV++I +R + ID +M W DKYQAQIVVLAAQI WSE VE++L ++ + V STLN+LAD+VL EQPP+RRRKLEHLI E+VH+R V R L N+GV+S K+F W+ +MRFYFDP+QT+ L QL+IH+ANA+F YGFEYLGV DRLVQTPLTDRCYLTMTQALE+RLGGSPFGPAGTGKTESVK+LGNQLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLSA SQQIQ IQEAL+ M S K+SI VEL+GKQV V+PDMAIFITMNPGYAGRSNLPDNLKKLFRSLAMT PDRQLIA+VML+SQGFR+AE LA K+VPFFKLCDEQLS QSHYDFGLRALKSVL+SAGNVKRDRI + KE++ RG+E I+E ++AE LPEQEILIQSV ETMVPKL+A+DIPLL+SLL+DVFP V Y +AEMK L+EE+RKV + +LV DE A G WV+KVLQLYQI+ ++HGLMMVGPSGSGK+ A + LL+ALE +G+EGVAH+IDPK+ISK++LYG +DPNTREWTDGLFTHILR+IID+VRGE NKRQWI+FDGDVDPEWVENLNSVLDDNKLLTLPNGERL++PPNVR+MFEVQDLK+ATLATVSRCGMVWFSE+VL+T MI ++L+ L+ + + +G+EDF G D + SP +Q+Q ++ +L PFF+ DG++ + L+Y+ EHIMDFTRLRAL+SLFSM+ Q+ RN++ +N H DFP + +Q+E+Y+ K+L+ SV+WS +GD+KLKVR L ++++++TV LP G IID+EVN+ G WV WSNKVP IEVETHK+ + D+VVPT+DTVRHE+LLYTWLAEH+P++LCGPPGSGKTMTLFSALR LPDMEVVGLNFSSATTPEL+LKTFD YCEYRKTPNG+VL+P Q+ KWL+ FCDEINLPDMD YGTQRVISFLRQ+VEH GFYR +D WVS ERIQFVGACNPPTDPGRKPLSHRFLRHVP++YVDYPGETSLKQIY TF+RAMLR++P+LRGYA+ LTNAMVEF+L +Q+RFT DMQPHY+YSPREMTRWVRGI EA++PL+SL VEGLVR+WAHEALRLFQDRLV++ ER WT++NI+ V KHFP IN+EEAL+RPILYSNWLSKDY V +EELR+YV ARLKVFYEEELDVPLVLF++VLDHVLRIDR+FRQPQGHLLLIGVSGAGKTTLSRFV+W+NGLS+FQ+KVHNKYT+EDFDEDLR VLRRSGCK EKI FI+DESNV+DS FLERMNTLLANGEVPGLFEGDE TTLMTQCKEGA REGLM+DS +ELYKWFTQQ+ RNLHVVFTMNPS DGLKD+A+TSPALFNRCVLNWFGDWS A FQVGKEFT R+DLE+ ++ PD P + L+P NP +RD V+N+ V+VHQT+HQAN R+ KRGGRT A+TPRHYLD I H++KL EKR+DLEEQQLHLN GL KI +TV+QVE MQ+SL K+QEL+ NEAANAKLKQM QDQQEAE+KK Q ++ LA Q + EK+K V +L QVEP V +A+ AV++IRK+ + E++ M NPP+ VK+A+ESICLLLGE TDW+SI VI+++ F+ SI+ NF T++++D+ RE MK KYLSNPDYNFEKVN+AS ACGPMVKW +AQI YAD+LKRVEPLR EL L + A+ N ++ET+DL+ QLE+SIA Y EEYA LISQAQ IK+DL +V++KV RS+ALL SL+ ER RW+S SETFK+QM+TI GD LLS+AF+AYGGYFDQH R +LF TW HL A I +R+D+AR EYLSNPD+RLRWQAN+LP DDLC ENAI+L+R+NRYPLIIDPSGQATTFLLNEY KKITKTSFLDDSFRK LESALRFG PLLVQDVE+YDPILNPVLNRE+RRTGGR LITLGDQDIDLSP+F IFLSTRDP+VEF PDICSRVTFVNFTVTRSSLQ+QCLN VLK ERPDID+KRSDLLK QGEF+L+LR LEK LLQ+LN+A+G +L++D +I LETLK+EA D+ +KV+ETD V+ E+E+VS +Y+PL+ +CSNIYFT++++NQ+HFLYQYSL++ LDIFS+VL NNP+L S+RL I+T++LFQV Y R+ARGM+H D++TFA ++ +I LKG++ L+ EF FLRS+E + +N GL+ +QI+SV RL +L +F K+ EKV+S ++ W +PE VP+LW + + LS IA ++ LL+IQA RPDR++A+ + +VLG+ F + LD S+V+ ++ P LLC+V G+D SGRV+DLA+EQ KQ++ IAIGSAEGF+QAE+AIN A KTG+WV+LKNVHLA WLV LEKK+HSLQ H FRLFLTMEI PK+PVNLLRAGR+ VFEPPPGI+ANLLRT S++ RM K P ER+RLYFLLAW +AIVQERLRYVPLG++KKYEF ESD + A DT+DTW+D AMGRTNLPPEK+PW AL TLL IYGGKIDN FDQRLL SFL LFT + F+ +FALV++ D S +I P+ T+ L+W+ L D QTPSWLGLPN+AEKVLLT G L+ +LKMQQ LEDD+EL VG DGRP+WM+ L+ S WL++LPK++ L+RT+ENIKDP+YR FEREV SG LL +V DL+DV +C+G KK TNHHRSM+++L +GIIPK W RY +P G TVIQWI DF++R++QL +S +++G L+ VWLGGL EAYITATRQ VAQ N W+LEEL LDV + + K D C +TGL+L G++ + L L++ I D+ + LKWI++ ++ K+ LP+YLN+ R+ +LFT L + S+ FY+RGVA+ Sbjct: 52 LDDPVNQDTIRKFLSDPQVQALYVQRNCIKEDDSEQPAEGEDEKEQVTYQISNDVHFTNSRMASLACIKRGLVVEADKSIHSQLRLINFSDGSPYETLHAFISKSLAPYFKSYVKESGRADRDGDK-MAPSVEKKLAELEMGLLHLQQNIDIPEITLTAHQTVNNVIRKCAEENRKAKVADFGDKVEDSSFLNLLQNGVNRWIAEIKKVTKLNRDPGSGTALQEISFWLNLERALYRIQEKRESPEVALTLDILKHGKRFHATVSFDTDTGLKQALATVADYNPLMKDFPINDLLSATELEKIRPAVQQIFAHLRKVRNTKYPIQRCLKLIEAISRDLSQQLLKVLGTRRLMHIPFDEFERVMNQCFEIFSCWDDEYDKLQGLLRDIVKKKRDEHLKMVWRVSPAHKKLQTRMEHMRKFRRQHEQLRTVILRVLRPT------------KPAVGDDGNVVETKQPYSLDAADANAIEEVNLAYENVKEVDCLDITKEGSEAWEAAVKRYEEKIDRVETRITAHLRDQLGTAKNANEMFRIFSRFNALFVRPHIRGAIREYQTQLIQRVKDDIEALHEKFKVQYPQSKSCRLSSVRDLPPVAGSIIWARQIDNQLTMYLKRVEDVLGKGWETHIEGQKLKADGDSFRAKLSISDVFHEWARKVQERNFGSTGRIFTIESTRSRIG-------RGNVLRLRVNFLPEIITLAKEVRNIKNLGFRVPLTIVNKAHQANQIYPYAISLIESVRTYERTLEKIEDRA--SIVPLVAGLRKDVLNLVSEGIGLIWESYKLDPYVIRLSECVTQFQEKVDDLLVVEEQLDVDVRSLETCPYSAATFVEILSKIQHAVDDLSLRQYSNLSVWVTRLDEEVEKKLALRLQAGIQAWTEALTGNKKEVDTSMDTD---APAQPTHKLGGDPQIQNAVHEIRITNQQMYLYPSIEEARFQIMQQFFAWQAIVTSQVRLQSTRYQVGLEKHVS--QTYRNLLTKLP-EGKILENAYGAIEQKVSEVRNYVDEWLRYQSLWDLQADMLYGRLGEDVNLWIKCLNDIKQSRTTFDTSDTRRAYGPIIIDYAKVQAKVTLKYDSWHKEALGKFGTLLGTEMTSFHSKVSKSRTDLEMQSIEAASTSDAVSFITYVQSLKKDMIAWDKQVEVFREAQRILERQRFQFPNTWLHVDNIEGEWSAFNEIIKRKDTAIQTQVASLQAKIVAEDKAVETRTVDFLNDWEKTKPTGGKIRPDDALQQLQIFESKYSRLKEERDNVVKAKEALELQESAVPNNSAERMNVALEELQDLRGVWSELSKVWTQIDETREKPWLSVQPRKLRQQLEAMMAQLKELPARLRMYESYEYVKKLIQSYIKVNMLIVELKSDALKERHWKQLTKQLRVNWVLSDLSLGQVWDVNLQKNEGIVKDIILVAQGEMALEEFLKQVRESWQNYELDLINYQNKCRIIRGWDDLFNKVKEHINSVAAMKLSPYYKVFEEEALTWEEKLNRINALFDVWIDVQRRWVYLEGIFSGSADIKTLLPVETSRFQSISSEFLGLMKKVTKSPKVMDVLNIPAVQRSLERLADLLGKIQKALGEYLERERTSFPRFYFVGDEDLLEIIGNSKNIARLQKHFKKMFAGVAAILLNEENNVILGISSREGEEVHFMNPVSTVEHPKINEWLSLVEKQMRFTLASLLAQAVQDIKQFR-DGKIDPQAYMEWCDKYQAQIVVLAAQILWSEDVESALQQASENNQSKPMQRVLGNVESTLNVLADSVLQEQPPLRRRKLEHLINEFVHKRTVTRRLLNNGVTSPKSFQWLCEMRFYFDPRQTEVLQQLTIHMANARFFYGFEYLGVQDRLVQTPLTDRCYLTMTQALESRLGGSPFGPAGTGKTESVKALGNQLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLSACSQQIQTIQEALKYEMDSNKESITVELVGKQVRVSPDMAIFITMNPGYAGRSNLPDNLKKLFRSLAMTTPDRQLIAEVMLFSQGFRSAEKLACKIVPFFKLCDEQLSNQSHYDFGLRALKSVLISAGNVKRDRIMKIKEQMKQRGDENIDEASVAENLPEQEILIQSVCETMVPKLVAEDIPLLFSLLSDVFPNVGYTRAEMKGLKEEIRKVCQEDYLVCGEGDEQGAAWMEKGLGSTWVDKVLQLYQISNLNHGLMMVGPSGSGKSTAWKTLLKALERFEGVEGVAHVIDPKAISKEALYGVLDPNTREWTDGLFTHILRKIIDNVRGEINKRQWIIFDGDVDPEWVENLNSVLDDNKLLTLPNGERLSLPPNVRVMFEVQDLKFATLATVSRCGMVWFSEDVLSTEMIFENYLSRLRSIPLEDGDEDFV---GVIKPAKDKEEEVSPSLQVQRDIALLLLPFFSADGIVVRTLEYAMDQEHIMDFTRLRALSSLFSMLNQAARNVLTFNAQHPDFPCSADQLEHYIPKALVYSVLWSFAGDAKLKVRIDLGDFVRSVTTVPLPGAAGAP-IIDYEVNMSGDWVPWSNKVPVIEVETHKVASPDIVVPTLDTVRHESLLYTWLAEHKPLVLCGPPGSGKTMTLFSALRALPDMEVVGLNFSSATTPELLLKTFDHYCEYRKTPNGVVLSPVQIGKWLVLFCDEINLPDMDSYGTQRVISFLRQLVEHKGFYRASDQAWVSLERIQFVGACNPPTDPGRKPLSHRFLRHVPIIYVDYPGETSLKQIYGTFSRAMLRLMPALRGYAEPLTNAMVEFYLASQDRFTQDMQPHYVYSPREMTRWVRGICEAIRPLDSLPVEGLVRLWAHEALRLFQDRLVDDSERRWTNENIDLVGQKHFPGINQEEALQRPILYSNWLSKDYMPVNREELREYVHARLKVFYEEELDVPLVLFDEVLDHVLRIDRIFRQPQGHLLLIGVSGAGKTTLSRFVAWMNGLSIFQIKVHNKYTSEDFDEDLRCVLRRSGCKDEKIAFILDESNVLDSGFLERMNTLLANGEVPGLFEGDEYTTLMTQCKEGAQREGLMLDSSDELYKWFTQQVMRNLHVVFTMNPSTDGLKDRAATSPALFNRCVLNWFGDWSDSALFQVGKEFTTRVDLEKPNWHAPDFFPSVCP-LVPANPTHRDAVINSCVYVHQTLHQANARLAKRGGRTMAVTPRHYLDFIHHFVKLYNEKRSDLEEQQLHLNVGLNKIAETVEQVEEMQKSLAVKKQELQAKNEAANAKLKQMFQDQQEAEKKKIQSQEIQIRLADQTVKIEEKRKYVMADLAQVEPAVIDAQAAVKSIRKQQLVEVRTMANPPSVVKLALESICLLLGENATDWKSIRAVIMRENFINSIVSNFGTENITDDVREKMKSKYLSNPDYNFEKVNRASMACGPMVKWAIAQIEYADMLKRVEPLREELRSLEEQADVNLASAKETKDLVEQLERSIAAYKEEYAQLISQAQAIKTDLENVQAKVDRSIALLKSLNIERERWESTSETFKSQMSTIIGDVLLSAAFIAYGGYFDQHYRLNLFTTWSQHLQAASIQYRADIARTEYLSNPDERLRWQANALPTDDLCTENAIMLKRFNRYPLIIDPSGQATTFLLNEYAGKKITKTSFLDDSFRKNLESALRFGNPLLVQDVENYDPILNPVLNRELRRTGGRVLITLGDQDIDLSPSFVIFLSTRDPTVEFPPDICSRVTFVNFTVTRSSLQSQCLNQVLKAERPDIDEKRSDLLKLQGEFRLRLRQLEKSLLQALNDAKGKILDDDSVITTLETLKKEAYDINQKVDETDKVIAEIETVSQQYLPLSVACSNIYFTMDSLNQVHFLYQYSLKMFLDIFSTVLYNNPKLEGRTDHSERLGIVTRDLFQVCYERVARGMIHIDRLTFALLMCKIHLKGTSESN-LDAEFNFFLRSREGLL----ANPTPVEGLS--AEQIESVNRLALRLPIFRKLLEKVRSIPELGAWLQQSSPEQVVPQLWDE-----SKALSPIASSVHQLLLIQAFRPDRVIAAAHNVVNTVLGEDFMPNAEQELDFTSVVDKQLNCNTPALLCSVPGFDASGRVDDLAAEQNKQISSIAIGSAEGFNQAERAINMACKTGRWVLLKNVHLAPQWLVQLEKKMHSLQPHSGFRLFLTMEINPKVPVNLLRAGRIFVFEPPPGIRANLLRTFSTVPAARMMKTPSERARLYFLLAWFHAIVQERLRYVPLGWAKKYEFNESDLRVACDTLDTWIDTTAMGRTNLPPEKVPWDALVTLLSQSIYGGKIDNDFDQRLLTSFLKKLFTARSFEADFALVANVDGASGGLRHITMPDGTRRDHFLKWIENLTDRQTPSWLGLPNNAEKVLLTTRGTDLVSKLLKMQQ-LEDDDELAYSVEDQSEQSAVGRGEDGRPSWMKTLHNSATAWLELLPKNLQVLKRTVENIKDPLYRYFEREVTSGSRLLQTVILDLQDVVLICQGEKKQTNHHRSMLSELVRGIIPKGWKRYTVPAGCTVIQWITDFSNRVQQLQKVSQLVSQAGAKELQGFPVWLGGLLNPEAYITATRQCVAQANSWSLEELALDVTITDAGLKNDQKDCCFGVTGLKLQGAQCKNNELL-LASTIMMDLPVTILKWIKISSEPRI------SKLTLPVYLNSTRTELLFTVDLAVAAGQESHSFYERGVAV 4641
BLAST of Cytoplasmic dynein 1 heavy chain 1 vs. Ensembl Fly
Match: Dhc64C (gene:FBgn0261797 transcript:FBtr0332747) HSP 1 Score: 6090.38 bits (15799), Expect = 0.000e+0 Identity = 2931/4647 (63.07%), Postives = 3658/4647 (78.72%), Query Frame = 3 Query: 240 LSEPQNEECLTKFINDNQVTTLTIQQT--------KRXXXXXXXXXXXXKISNEVNFESNKSQTSIFIKNNQVIEADKTISSQLQVLSYCDGPPFETMHSLVCYGLLPYFXXXXXXXXXXXXXXXXXMVPSVEKKIAELEIGLLHLQQNIEIPEITLTPHPYVAHIIQEKLLQNKEARVSDFEDKFEDTQFLNQLQAGVNRWIKEIQKVTKLNRDPSTGTALQEISFWLNLEHSLDKIQEKRESLEVALTLAILKQAKRFHATTSFDTDTALSSAKIQVKDYNQLMKDFPINDLLSASQLDKISEALQQIFSHLKKVRATKYPVNRIIKLMEALSRDLTTQLMKVISNMHLMSMPYDEFEKIFTACQQVFSTWEDEYDKMQNLLRDIAKKKREEFTKFAWKMNATHKKLQTRLENIKKFRYQHEQLRQVIVRVLKPVTKVVPSVEAGVPKDQITDKGDKSSTFLP---ESADTSSIDEVNAAYEIVKVIDCLDFAKEENDEWDAAIKRYEERIDRVESRIASHLRDLLGQSKNANEMFRYFSRFNALFVRPHIRGAIGEYQTQLIQRVKDDIEALHNKFKVQYASSTACKMSKVRDLPPVSGSIIWVRQILRQLNAYMKRVEDVLGKDWAQHIEGQKLKADGESFKLKLNTSELFEEWSKKVAEKSLSVAGSIFNVESTRTVVTVRDREPQKITVLKLKVNFLPDVITLAKEVRNMRALGFRTPLSIVNKAHSANQLYPFAISLIESVRTYESTCSKIEEHKMQNISL-----------LTAGLRKDVQLCIHEGVQITWESYRLDQYVQKLAELVFSFQEKVDDLVIVIKEIDFNVKALETCSYNKQTFEEILIRIQEAVDNMSLHQFSNLAQWVSNLDSLVEQRLIVRLEAGLLEWIKVLKGXXXXXXXXXXXXXXXVNSMAKHRLGGKPQIKKLIHELRITNQQMHLYPSIEVATQDILYQMSSWQNIILNLSRIVHSRYQVGLETESDNQKTYKKLLSSLPNSGESLENAYAAVHNILRDANEYVKTWTNYQSLWDLQGDQLFSLIADDNTVWMNVLEEIKSMRKHFDVAETQKEFGPLVIAFGKVQSKVSMKYDNWHKEVLTKFGQNMGKMMTTLYNEVQRARNELEQQSIDSGGTNESVNFITYTQNIKRKMNTWEKQAEACRAGQNILCRDRFQFPNDWLDSENIQGEWSAFKEIMRRKQETISSQVASLQMKITEEDKIVESKTTEVLGNWEKDKPIAGDLTPEEAVNIIQILEGKFNRLKEERENVQKAKEALELTEIGVKPISEEKVTNALSELHDLKNVWNELKSIWEKIRDMKETPWLSVQPRKLRQDIENLTAQLKELPNSFKQYASFEHVRTLLKMYMKVNASIVELKSEAIKERHWRMLMRKLNVSWSLNELQLGKVWDIDLVKNEEIIREVLAIAQGEKALEEYLRQITEVWKNYVLELTNYQSKSKIIKGWDDLFNKVKEHINNVTSMKASPYFKQFEEEATAWEDRLNKINALFDVWIDVQRRWIYLDGIFAGSADIKVLLPVESQRFQSVSTEFLGLMKKVQKSPLVTDVLNIANVQRQLERLADLLGKIQKSLGEYLERQRSSFPRFYFVGDEDLLEIIGNSXXXXXXXXXXXXMFAGVHSIILSEDEKVILGMMSKEGEELRFISPVSIIEHPRINDWLTAMEKEMRVSLAKYLNVAVKEISGWRTESNIDKDKFMVWLDKYQAQIVVLAAQITWSEAVEASLASGVS------LESTMTVVHSTLNMLADTVLYEQPPVRRRKLEHLIIEYVHQRDVLRALHNDGVSSNKNFDWMSQMRFYFDPKQTDPLHQLSIHVANAKFHYGFEYLGVCDRLVQTPLTDRCYLTMTQALEARLGGSPFGPAGTGKTESVKSLGNQLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLSAVSQQIQGIQEALRELMVSKKDSINVELLGKQVHVNPDMAIFITMNPGYAGRSNLPDNLKKLFRSLAMTQPDRQLIAQVMLYSQGFRTAEVLAGKVVPFFKLCDEQLSPQSHYDFGLRALKSVLVSAGNVKRDRIKQEKEKIVARGEE-INETAIAEQLPEQEILIQSVMETMVPKLIADDIPLLYSLLTDVFPGVEYRQAEMKRLREELRKVSENKFLVYSDEPNTAGYLWVEKVLQLYQITTIHHGLMMVGPSGSGKTMACRVLLQALENIDGIEGVAHIIDPKSISKDSLYGYMDPNTREWTDGLFTHILRRIIDSVRGESNKRQWIVFDGDVDPEWVENLNSVLDDNKLLTLPNGERLAIPPNVRIMFEVQDLKYATLATVSRCGMVWFSEEVLTTGMILTHFLNELKKVQVMEGEEDFSVNQGDTGADADSKISSSPIIQLQTQVSSILAPFFTEDGLIAKCLDYSTTLEHIMDFTRLRALTSLFSMIKQSIRNMIEYNQSHSDFPLNNEQIENYVAKSLISSVVWSMSGDSKLKVREQLSQYIKNISTVDLPTVGGIKNIIDFEVNIQGTWVAWSNKVPQIEVETHKITATDVVVPTMDTVRHEALLYTWLAEHRPVLLCGPPGSGKTMTLFSALRCLPDMEVVGLNFSSATTPELMLKTFDQYCEYRKTPNGIVLAPQQLNKWLIFFCDEINLPDMDKYGTQRVISFLRQMVEHHGFYRITDMQWVSFERIQFVGACNPPTDPGRKPLSHRFLRHVPVVYVDYPGETSLKQIYSTFNRAMLRMLPSLRGYADTLTNAMVEFFLKTQERFTHDMQPHYIYSPREMTRWVRGIHEALKPLESLSVEGLVRIWAHEALRLFQDRLVEEDERHWTDDNINEVALKHFPNINKEEALKRPILYSNWLSKDYSAVTQEELRDYVKARLKVFYEEELDVPLVLFNQVLDHVLRIDRVFRQPQGHLLLIGVSGAGKTTLSRFVSWINGLSVFQVKVHNKYTAEDFDEDLRNVLRRSGCKGEKITFIMDESNVMDSSFLERMNTLLANGEVPGLFEGDELTTLMTQCKEGAIREGLMIDSQEELYKWFTQQICRNLHVVFTMNPSADGLKDKASTSPALFNRCVLNWFGDWSLEAYFQVGKEFTNRLDLERTDYKVPDTLPCIAEGLLPQNPIYRDVVVNALVFVHQTMHQANVRVQKRGGRTAAITPRHYLDLIAHYMKLSAEKRADLEEQQLHLNNGLKKIEQTVDQVEVMQRSLTKKRQELENMNEAANAKLKQMVQDQQEAEQKKTTGQALKEELAKQEQFVNEKQKTVKQELDQVEPTVNEAKQAVQNIRKKDIQEIKAMKNPPNAVKMAVESICLLLGEKTTDWQSILKVIIKDTFVTSIL-NFNTDDVSDNTRETMKKKYLSNPDYNFEKVNKASNACGPMVKWVLAQISYADILKRVEPLRNELTELSDAAEQNRKKSQETEDLIAQLEKSIAKYTEEYATLISQAQTIKSDLASVESKVGRSVALLGSLSSERTRWDSGSETFKAQMATINGDCLLSSAFMAYGGYFDQHMRTSLFNTWCHHLSEADILFRSDLARVEYLSNPDDRLRWQANSLPADDLCVENAIILRRYNRYPLIIDPSGQATTFLLNEYKEKKITKTSFLDDSFRKTLESALRFGTPLLVQDVESYDPILNPVLNREVRRTGGRTLITLGDQDIDLSPTFTIFLSTRDPSVEFAPDICSRVTFVNFTVTRSSLQNQCLNAVLKIERPDIDQKRSDLLKAQGEFQLKLRHLEKDLLQSLNEAQGNLLENDKIIARLETLKREAADVAKKVEETDVVMQEVESVSTEYVPLAQSCSNIYFTLEAMNQIHFLYQYSLQLMLDIFSSVLINNPELTNVKAASDRLKIITKNLFQVTYNRLARGMLHEDQITFATILARIFLKGSTPIGFLENEFQHFLRSQEATITSSDSNKQDNLGLTLHQDQIDSVKRLK-KLKVFAKIEEKVKSTKDIKNWTLTVTPESNVPELWVDDNNYNDEKLSKIAKGMYNLLIIQAIRPDRLLASTQKFIASVLGDTFTESVRGTLDLASIVEVEVTACVPILLCAVQGYDPSGRVEDLASEQGKQLTGIAIGSAEGFSQAEKAINSAAKTGKWVMLKNVHLATSWLVSLEKKIHSLQAHPNFRLFLTMEITPKLPVNLLRAGRVLVFEPPPGIKANLLRTLSSINNQRMSKEPVERSRLYFLLAWLNAIVQERLRYVPLGYSKKYEFGESDFKCALDTIDTWVDGAAMGRTNLPPEKIPWVALQTLLGSCIYGGKIDNAFDQRLLNSFLGYLFTEKCFDHNFALVSDADDGS----NIAFPESTKHTDILQWVHKLPDLQTPSWLGLPNSAEKVLLTNLGQSLIGNILKMQQSLEDDEELVVGQSKTKRTIEVG---DGRPAWMRQLYQSTQTWLQILPKSVTPLQRTIENIKDPMYRCFEREVNSGCNLLASVRKDLEDVAEVCKGAKKPTNHHRSMMADLAKGIIPKMWIRYAIPPGLTVIQWIQDFADRIKQLLHISDTAAKSGVIALRSIQVWLGGLFMAEAYITATRQSVAQNNKWALEELFLDVELGEG--KVDSNTCV--ITGLRLMGSEIVDPRTLKLSTLIYKDIDICRLKWIRVEKSQQLEGSSAKDKVCLPIYLNAARSTVLFT--LYFSTTDSSYDFYKRGVAI 14048 L +P N++ + KF++D QV L +Q+ + E E + + ++ISN+V+F +++ + IK V+EADK+I SQL+++++ DG P+ET+H+ + L PYFKSY+K+ G+ M PSVEKK+AELE+GLLHLQQNI+IPEITLT H V ++I++ +N++A+V+DF DK ED+ FLN LQ GVNRWI EI+KVTKLNRDP +GTALQEISFWLNLE +L +IQEKRES EVALTL ILK KRFHAT SFDTDT L A V DYN LMKDFPINDLLSA++L+KI A+QQIF+HL+KVR TKYP+ R +KL+EA+SRDL+ QL+KV+ LM +P+DEFE++ C ++FS W+DEYDK+Q LLRDI KKKR+E K W+++ HKKLQTR+E+++KFR QHEQLR VI+RVL+P K + D G+ T P ++AD ++I+EVN AYE VK +DCLD KE ++ W+AA+KRYEE+IDRVE+RI +HLRD LG +KNANEMFR FSRFNALFVRPHIRGAI EYQTQLIQRVKDDIEALH KFKVQY S +C++S VRDLPPV+GSIIW RQI QL Y+KRVEDVLGK W HIEGQKLKADG+SF+ KL+ S++F EW++KV E++ G IF +ESTR+ + + VL+L+VNFLP++ITLAKEVRN++ LGFR PL+IVNKAH ANQ+YP+AISLIESVRTYE T K+ + S+ L AGLRKDV + EG+ + WESY+LD YV +L+E V FQEKVDDL++V +++D +V++LETC Y+ TF EIL +IQ AVD++SL Q+SNL+ WV+ LD VE++L +RL+AG+ W + L G +E + + H+LGG PQI+ +HE+RITNQQM+LYPSIE A I+ Q +WQ I+ + R+ +RYQVGLE +TY+ LL+ LP G+ LENAY A+ + + YV W YQSLWDLQ D L+ + +D +W+ L +IK R FD ++T++ +GP++I + KVQ+KV++KYD+WHKE L KFG +G MT+ +++V ++R +LE QSI++ T+++V+FITY Q++K+ M W+KQ E R Q IL R RFQFPN WL +NI+GEWSAF EI++RK I +QVASLQ KI EDK VE++T + L +WEK KP G + P++A+ +QI E K++RLKEER+NV KAKEALEL E V S E++ AL EL DL+ VW+EL +W +I + +E PWLSVQPRKLRQ +E + AQLKELP + Y S+E+V+ L++ Y+KVN IVELKS+A+KERHW+ L ++L V+W L++L LG+VWD++L KNE I+++++ +AQGE ALEE+L+Q+ E W+NY L+L NYQ+K +II+GWDDLFNKVKEHIN+V +MK SPY+K FEEEA WE++LN+INALFDVWIDVQRRW+YL+GIF+GSADIK LLPVE+ RFQS+S+EFLGLMKKV KSP V DVLNI VQR LERLADLLGKIQK+LGEYLER+R+SFPRFYFVGDEDLLEIIGNSK++ +LQKHFKKMFAGV +I+L+E+ VILG+ S+EGEE+ F++PVS +EHP+IN+WL+ +EK+MR +LA L AV++I +R + ID +M W DKYQAQIVVLAAQI WSE VE++L ++ + V STLN+LAD+VL EQPP+RRRKLEHLI E+VH+R V R L N+GV+S K+F W+ +MRFYFDP+QT+ L QL+IH+ANA+F YGFEYLGV DRLVQTPLTDRCYLTMTQALE+RLGGSPFGPAGTGKTESVK+LGNQLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLSA SQQIQ IQEAL+ M S K+SI VEL+GKQV V+PDMAIFITMNPGYAGRSNLPDNLKKLFRSLAMT PDRQLIA+VML+SQGFR+AE LA K+VPFFKLCDEQLS QSHYDFGLRALKSVL+SAGNVKRDRI + KE++ RG+E I+E ++AE LPEQEILIQSV ETMVPKL+A+DIPLL+SLL+DVFP V Y +AEMK L+EE+RKV + +LV E + G W+EKVLQLYQI+ ++HGLMMVGPSGSGK+ A + LL+ALE +G+EGVAH+IDPK+ISK++LYG +DPNTREWTDGLFTHILR+IID+VRGE NKRQWI+FDGDVDPEWVENLNSVLDDNKLLTLPNGERL++PPNVR+MFEVQDLK+ATLATVSRCGMVWFSE+VL+T MI ++L+ L+ + + +G+EDF G D + SP +Q+Q ++ +L PFF+ DG++ + L+Y+ EHIMDFTRLRAL+SLFSM+ Q+ RN++ +N H DFP + +Q+E+Y+ K+L+ SV+WS +GD+KLKVR L ++++++TV LP G IID+EVN+ G WV WSNKVP IEVETHK+ + D+VVPT+DTVRHE+LLYTWLAEH+P++LCGPPGSGKTMTLFSALR LPDMEVVGLNFSSATTPEL+LKTFD YCEYRKTPNG+VL+P Q+ KWL+ FCDEINLPDMD YGTQRVISFLRQ+VEH GFYR +D WVS ERIQFVGACNPPTDPGRKPLSHRFLRHVP++YVDYPGETSLKQIY TF+RAMLR++P+LRGYA+ LTNAMVEF+L +Q+RFT DMQPHY+YSPREMTRWVRGI EA++PL+SL VEGLVR+WAHEALRLFQDRLV++ ER WT++NI+ V KHFP IN+EEAL+RPILYSNWLSKDY V +EELR+YV ARLKVFYEEELDVPLVLF++VLDHVLRIDR+FRQPQGHLLLIGVSGAGKTTLSRFV+W+NGLS+FQ+KVHNKYT+EDFDEDLR VLRRSGCK EKI FI+DESNV+DS FLERMNTLLANGEVPGLFEGDE TTLMTQCKEGA REGLM+DS +ELYKWFTQQ+ RNLHVVFTMNPS DGLKD+A+TSPALFNRCVLNWFGDWS A FQVGKEFT R+DLE+ ++ PD P + L+P NP +RD V+N+ V+VHQT+HQAN R+ KRGGRT A+TPRHYLD I H++KL EKR+DLEEQQLHLN GL KI +TV+QVE MQ+SL K+QEL+ NEAANAKLKQM QDQQEAE+KK Q ++ LA Q + EK+K V +L QVEP V +A+ AV++IRK+ + E++ M NPP+ VK+A+ESICLLLGE TDW+SI VI+++ F+ SI+ NF T++++D+ RE MK KYLSNPDYNFEKVN+AS ACGPMVKW +AQI YAD+LKRVEPLR EL L + A+ N ++ET+DL+ QLE+SIA Y EEYA LISQAQ IK+DL +V++KV RS+ALL SL+ ER RW+S SETFK+QM+TI GD LLS+AF+AYGGYFDQH R +LF TW HL A I +R+D+AR EYLSNPD+RLRWQAN+LP DDLC ENAI+L+R+NRYPLIIDPSGQATTFLLNEY KKITKTSFLDDSFRK LESALRFG PLLVQDVE+YDPILNPVLNRE+RRTGGR LITLGDQDIDLSP+F IFLSTRDP+VEF PDICSRVTFVNFTVTRSSLQ+QCLN VLK ERPDID+KRSDLLK QGEF+L+LR LEK LLQ+LN+A+G +L++D +I LETLK+EA D+ +KV+ETD V+ E+E+VS +Y+PL+ +CSNIYFT++++NQ+HFLYQYSL++ LDIFS+VL NNP+L S+RL I+T++LFQV Y R+ARGM+H D++TFA ++ +I LKG++ L+ EF FLRS+E + +N GL+ +QI+SV RL +L +F K+ EKV+S ++ W +PE VP+LW + + LS IA ++ LL+IQA RPDR++A+ + +VLG+ F + LD S+V+ ++ P LLC+V G+D SGRV+DLA+EQ KQ++ IAIGSAEGF+QAE+AIN A KTG+WV+LKNVHLA WLV LEKK+HSLQ H FRLFLTMEI PK+PVNLLRAGR+ VFEPPPGI+ANLLRT S++ RM K P ER+RLYFLLAW +AIVQERLRYVPLG++KKYEF ESD + A DT+DTW+D AMGRTNLPPEK+PW AL TLL IYGGKIDN FDQRLL SFL LFT + F+ +FALV++ D S +I P+ T+ L+W+ L D QTPSWLGLPN+AEKVLLT G L+ +LKMQQ LEDD+EL VG DGRP+WM+ L+ S WL++LPK++ L+RT+ENIKDP+YR FEREV SG LL +V DL+DV +C+G KK TNHHRSM+++L +GIIPK W RY +P G TVIQWI DF++R++QL +S +++G L+ VWLGGL EAYITATRQ VAQ N W+LEEL LDV + + K D C +TGL+L G++ + L L++ I D+ + LKWI++ ++ K+ LP+YLN+ R+ +LFT L + S+ FY+RGVA+ Sbjct: 52 LDDPVNQDTIRKFLSDPQVQALYVQRNCIKEDDSEQPAEGEDEKEQVTYQISNDVHFTNSRMASLACIKRGLVVEADKSIHSQLRLINFSDGSPYETLHAFISKSLAPYFKSYVKESGRADRDGDK-MAPSVEKKLAELEMGLLHLQQNIDIPEITLTAHQTVNNVIRKCAEENRKAKVADFGDKVEDSSFLNLLQNGVNRWIAEIKKVTKLNRDPGSGTALQEISFWLNLERALYRIQEKRESPEVALTLDILKHGKRFHATVSFDTDTGLKQALATVADYNPLMKDFPINDLLSATELEKIRPAVQQIFAHLRKVRNTKYPIQRCLKLIEAISRDLSQQLLKVLGTRRLMHIPFDEFERVMNQCFEIFSCWDDEYDKLQGLLRDIVKKKRDEHLKMVWRVSPAHKKLQTRMEHMRKFRRQHEQLRTVILRVLRPT------------KPAVGDDGNVVETKQPYSLDAADANAIEEVNLAYENVKEVDCLDITKEGSEAWEAAVKRYEEKIDRVETRITAHLRDQLGTAKNANEMFRIFSRFNALFVRPHIRGAIREYQTQLIQRVKDDIEALHEKFKVQYPQSKSCRLSSVRDLPPVAGSIIWARQIDNQLTMYLKRVEDVLGKGWETHIEGQKLKADGDSFRAKLSISDVFHEWARKVQERNFGSTGRIFTIESTRSRIG-------RGNVLRLRVNFLPEIITLAKEVRNIKNLGFRVPLTIVNKAHQANQIYPYAISLIESVRTYERTLEKLNNRSLAQNSVFKIEDRASIVPLVAGLRKDVLNLVSEGIGLIWESYKLDPYVIRLSECVTQFQEKVDDLLVVEEQLDVDVRSLETCPYSAATFVEILSKIQHAVDDLSLRQYSNLSVWVTRLDEEVEKKLALRLQAGIQAWTEALTGNKKEVDTSMDTD---APAQPTHKLGGDPQIQNAVHEIRITNQQMYLYPSIEEARFQIMQQFFAWQAIVTSQVRLQSTRYQVGLEKHVS--QTYRNLLTKLP-EGKILENAYGAIEQKVSEVRNYVDEWLRYQSLWDLQADMLYGRLGEDVNLWIKCLNDIKQSRTTFDTSDTRRAYGPIIIDYAKVQAKVTLKYDSWHKEALGKFGTLLGTEMTSFHSKVSKSRTDLEMQSIEAASTSDAVSFITYVQSLKKDMIAWDKQVEVFREAQRILERQRFQFPNTWLHVDNIEGEWSAFNEIIKRKDTAIQTQVASLQAKIVAEDKAVETRTVDFLNDWEKTKPTGGKIRPDDALQQLQIFESKYSRLKEERDNVVKAKEALELQESAVPNNSAERMNVALEELQDLRGVWSELSKVWTQIDETREKPWLSVQPRKLRQQLEAMMAQLKELPARLRMYESYEYVKKLIQSYIKVNMLIVELKSDALKERHWKQLTKQLRVNWVLSDLSLGQVWDVNLQKNEGIVKDIILVAQGEMALEEFLKQVRESWQNYELDLINYQNKCRIIRGWDDLFNKVKEHINSVAAMKLSPYYKVFEEEALTWEEKLNRINALFDVWIDVQRRWVYLEGIFSGSADIKTLLPVETSRFQSISSEFLGLMKKVTKSPKVMDVLNIPAVQRSLERLADLLGKIQKALGEYLERERTSFPRFYFVGDEDLLEIIGNSKNIARLQKHFKKMFAGVAAILLNEENNVILGISSREGEEVHFMNPVSTVEHPKINEWLSLVEKQMRFTLASLLAQAVQDIKQFR-DGKIDPQAYMEWCDKYQAQIVVLAAQILWSEDVESALQQASENNQSKPMQRVLGNVESTLNVLADSVLQEQPPLRRRKLEHLINEFVHKRTVTRRLLNNGVTSPKSFQWLCEMRFYFDPRQTEVLQQLTIHMANARFFYGFEYLGVQDRLVQTPLTDRCYLTMTQALESRLGGSPFGPAGTGKTESVKALGNQLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLSACSQQIQTIQEALKYEMDSNKESITVELVGKQVRVSPDMAIFITMNPGYAGRSNLPDNLKKLFRSLAMTTPDRQLIAEVMLFSQGFRSAEKLACKIVPFFKLCDEQLSNQSHYDFGLRALKSVLISAGNVKRDRIMKIKEQMKQRGDENIDEASVAENLPEQEILIQSVCETMVPKLVAEDIPLLFSLLSDVFPNVGYTRAEMKGLKEEIRKVCQEDYLV-CGEGDEQGAAWMEKVLQLYQISNLNHGLMMVGPSGSGKSTAWKTLLKALERFEGVEGVAHVIDPKAISKEALYGVLDPNTREWTDGLFTHILRKIIDNVRGEINKRQWIIFDGDVDPEWVENLNSVLDDNKLLTLPNGERLSLPPNVRVMFEVQDLKFATLATVSRCGMVWFSEDVLSTEMIFENYLSRLRSIPLEDGDEDFV---GVIKPAKDKEEEVSPSLQVQRDIALLLLPFFSADGIVVRTLEYAMDQEHIMDFTRLRALSSLFSMLNQAARNVLTFNAQHPDFPCSADQLEHYIPKALVYSVLWSFAGDAKLKVRIDLGDFVRSVTTVPLPGAAGAP-IIDYEVNMSGDWVPWSNKVPVIEVETHKVASPDIVVPTLDTVRHESLLYTWLAEHKPLVLCGPPGSGKTMTLFSALRALPDMEVVGLNFSSATTPELLLKTFDHYCEYRKTPNGVVLSPVQIGKWLVLFCDEINLPDMDSYGTQRVISFLRQLVEHKGFYRASDQAWVSLERIQFVGACNPPTDPGRKPLSHRFLRHVPIIYVDYPGETSLKQIYGTFSRAMLRLMPALRGYAEPLTNAMVEFYLASQDRFTQDMQPHYVYSPREMTRWVRGICEAIRPLDSLPVEGLVRLWAHEALRLFQDRLVDDSERRWTNENIDLVGQKHFPGINQEEALQRPILYSNWLSKDYMPVNREELREYVHARLKVFYEEELDVPLVLFDEVLDHVLRIDRIFRQPQGHLLLIGVSGAGKTTLSRFVAWMNGLSIFQIKVHNKYTSEDFDEDLRCVLRRSGCKDEKIAFILDESNVLDSGFLERMNTLLANGEVPGLFEGDEYTTLMTQCKEGAQREGLMLDSSDELYKWFTQQVMRNLHVVFTMNPSTDGLKDRAATSPALFNRCVLNWFGDWSDSALFQVGKEFTTRVDLEKPNWHAPDFFPSVCP-LVPANPTHRDAVINSCVYVHQTLHQANARLAKRGGRTMAVTPRHYLDFIHHFVKLYNEKRSDLEEQQLHLNVGLNKIAETVEQVEEMQKSLAVKKQELQAKNEAANAKLKQMFQDQQEAEKKKIQSQEIQIRLADQTVKIEEKRKYVMADLAQVEPAVIDAQAAVKSIRKQQLVEVRTMANPPSVVKLALESICLLLGENATDWKSIRAVIMRENFINSIVSNFGTENITDDVREKMKSKYLSNPDYNFEKVNRASMACGPMVKWAIAQIEYADMLKRVEPLREELRSLEEQADVNLASAKETKDLVEQLERSIAAYKEEYAQLISQAQAIKTDLENVQAKVDRSIALLKSLNIERERWESTSETFKSQMSTIIGDVLLSAAFIAYGGYFDQHYRLNLFTTWSQHLQAASIQYRADIARTEYLSNPDERLRWQANALPTDDLCTENAIMLKRFNRYPLIIDPSGQATTFLLNEYAGKKITKTSFLDDSFRKNLESALRFGNPLLVQDVENYDPILNPVLNRELRRTGGRVLITLGDQDIDLSPSFVIFLSTRDPTVEFPPDICSRVTFVNFTVTRSSLQSQCLNQVLKAERPDIDEKRSDLLKLQGEFRLRLRQLEKSLLQALNDAKGKILDDDSVITTLETLKKEAYDINQKVDETDKVIAEIETVSQQYLPLSVACSNIYFTMDSLNQVHFLYQYSLKMFLDIFSTVLYNNPKLEGRTDHSERLGIVTRDLFQVCYERVARGMIHIDRLTFALLMCKIHLKGTSESN-LDAEFNFFLRSREGLL----ANPTPVEGLS--AEQIESVNRLALRLPIFRKLLEKVRSIPELGAWLQQSSPEQVVPQLWDE-----SKALSPIASSVHQLLLIQAFRPDRVIAAAHNVVNTVLGEDFMPNAEQELDFTSVVDKQLNCNTPALLCSVPGFDASGRVDDLAAEQNKQISSIAIGSAEGFNQAERAINMACKTGRWVLLKNVHLAPQWLVQLEKKMHSLQPHSGFRLFLTMEINPKVPVNLLRAGRIFVFEPPPGIRANLLRTFSTVPAARMMKTPSERARLYFLLAWFHAIVQERLRYVPLGWAKKYEFNESDLRVACDTLDTWIDTTAMGRTNLPPEKVPWDALVTLLSQSIYGGKIDNDFDQRLLTSFLKKLFTARSFEADFALVANVDGASGGLRHITMPDGTRRDHFLKWIENLTDRQTPSWLGLPNNAEKVLLTTRGTDLVSKLLKMQQ-LEDDDELAYSVEDQSEQSAVGRGEDGRPSWMKTLHNSATAWLELLPKNLQVLKRTVENIKDPLYRYFEREVTSGSRLLQTVILDLQDVVLICQGEKKQTNHHRSMLSELVRGIIPKGWKRYTVPAGCTVIQWITDFSNRVQQLQKVSQLVSQAGAKELQGFPVWLGGLLNPEAYITATRQCVAQANSWSLEELALDVTITDAGLKNDQKDCCFGVTGLKLQGAQCKNNELL-LASTIMMDLPVTILKWIKISSEPRI------SKLTLPVYLNSTRTELLFTVDLAVAAGQESHSFYERGVAV 4645
BLAST of Cytoplasmic dynein 1 heavy chain 1 vs. Ensembl Fly
Match: Dhc64C (gene:FBgn0261797 transcript:FBtr0332750) HSP 1 Score: 6089.61 bits (15797), Expect = 0.000e+0 Identity = 2933/4655 (63.01%), Postives = 3659/4655 (78.60%), Query Frame = 3 Query: 240 LSEPQNEECLTKFINDNQVTTLTIQQT--------KRXXXXXXXXXXXXKISNEVNFESNKSQTSIFIKNNQVIEADKTISSQLQVLSYCDGPPFETMHSLVCYGLLPYFXXXXXXXXXXXXXXXXXMVPSVEKKIAELEIGLLHLQQNIEIPEITLTPHPYVAHIIQEKLLQNKEARVSDFEDKFEDTQFLNQLQAGVNRWIKEIQKVTKLNRDPSTGTALQEISFWLNLEHSLDKIQEKRESLEVALTLAILKQAKRFHATTSFDTDTALSSAKIQVKDYNQLMKDFPINDLLSASQLDKISEALQQIFSHLKKVRATKYPVNRIIKLMEALSRDLTTQLMKVISNMHLMSMPYDEFEKIFTACQQVFSTWEDEYDKMQNLLRDIAKKKREEFTKFAWKMNATHKKLQTRLENIKKFRYQHEQLRQVIVRVLKPVTKVVPSVEAGVPKDQITDKGDKSSTFLP---ESADTSSIDEVNAAYEIVKVIDCLDFAKEENDEWDAAIKRYEERIDRVESRIASHLRDLLGQSKNANEMFRYFSRFNALFVRPHIRGAIGEYQTQLIQRVKDDIEALHNKFKVQYASSTACKMSKVRDLPPVSGSIIWVRQILRQLNAYMKRVEDVLGKDWAQHIEGQKLKADGESFKLKLNTSELFEEWSKKVAEKSLSVAGSIFNVESTRTVVTVRDREPQKITVLKLKVNFLPDVITLAKEVRNMRALGFRTPLSIVNKAHSANQLYPFAISLIESVRTYESTCSKIEEHKMQNISL-----------LTAGLRKDVQLCIHEGVQITWESYRLDQYVQKLAELVFSFQEKVDDLVIVIKEIDFNVKALETCSYNKQTFEEILIRIQEAVDNMSLHQFSNLAQWVSNLDSLVEQRLIVRLEAGLLEWIKVLKGXXXXXXXXXXXXXXXVNSMAKHRLGGKPQIKKLIHELRITNQQMHLYPSIEVATQDILYQMSSWQNIILNLSRIVHSRYQVGLETESDNQKTYKKLLSSLPNSGESLENAYAAVHNILRDANEYVKTWTNYQSLWDLQGDQLFSLIADDNTVWMNVLEEIKSMRKHFDVAETQKEFGPLVIAFGKVQSKVSMKYDNWHKEVLTKFGQNMGKMMTTLYNEVQRARNELEQQSIDSGGTNESVNFITYTQNIKRKMNTWEKQAEACRAGQNILCRDRFQFPNDWLDSENIQGEWSAFKEIMRRKQETISSQVASLQMKITEEDKIVESKTTEVLGNWEKDKPIAGDLTPEEAVNIIQILEGKFNRLKEERENVQKAKEALELTEIGVKPISEEKVTNALSELHDLKNVWNELKSIWEKIRDMKETPWLSVQPRKLRQDIENLTAQLKELPNSFKQYASFEHVRTLLKMYMKVNASIVELKSEAIKERHWRMLMRKLNVSWSLNELQLGKVWDIDLVKNEEIIREVLAIAQGEKALEEYLRQITEVWKNYVLELTNYQSKSKIIKGWDDLFNKVKEHINNVTSMKASPYFKQFEEEATAWEDRLNKINALFDVWIDVQRRWIYLDGIFAGSADIKVLLPVESQRFQSVSTEFLGLMKKVQKSPLVTDVLNIANVQRQLERLADLLGKIQKSLGEYLERQRSSFPRFYFVGDEDLLEIIGNSXXXXXXXXXXXXMFAGVHSIILSEDEKVILGMMSKEGEELRFISPVSIIEHPRINDWLTAMEKEMRVSLAKYLNVAVKEISGWRTESNIDKDKFMVWLDKYQAQIVVLAAQITWSEAVEASLASGVS------LESTMTVVHSTLNMLADTVLYEQPPVRRRKLEHLIIEYVHQRDVLRALHNDGVSSNKNFDWMSQMRFYFDPKQTDPLHQLSIHVANAKFHYGFEYLGVCDRLVQTPLTDRCYLTMTQALEARLGGSPFGPAGTGKTESVKSLGNQLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLSAVSQQIQGIQEALRELMVSKKDSINVELLGKQVHVNPDMAIFITMNPGYAGRSNLPDNLKKLFRSLAMTQPDRQLIAQVMLYSQGFRTAEVLAGKVVPFFKLCDEQLSPQSHYDFGLRALKSVLVSAGNVKRDRIKQEKEKIVARGEE-INETAIAEQLPEQEILIQSVMETMVPKLIADDIPLLYSLLTDVFPGVEYRQAEMKRLREELRKVSENKFLVYS--DEPNTA------GYLWVEKVLQLYQITTIHHGLMMVGPSGSGKTMACRVLLQALENIDGIEGVAHIIDPKSISKDSLYGYMDPNTREWTDGLFTHILRRIIDSVRGESNKRQWIVFDGDVDPEWVENLNSVLDDNKLLTLPNGERLAIPPNVRIMFEVQDLKYATLATVSRCGMVWFSEEVLTTGMILTHFLNELKKVQVMEGEEDFSVNQGDTGADADSKISSSPIIQLQTQVSSILAPFFTEDGLIAKCLDYSTTLEHIMDFTRLRALTSLFSMIKQSIRNMIEYNQSHSDFPLNNEQIENYVAKSLISSVVWSMSGDSKLKVREQLSQYIKNISTVDLPTVGGIKNIIDFEVNIQGTWVAWSNKVPQIEVETHKITATDVVVPTMDTVRHEALLYTWLAEHRPVLLCGPPGSGKTMTLFSALRCLPDMEVVGLNFSSATTPELMLKTFDQYCEYRKTPNGIVLAPQQLNKWLIFFCDEINLPDMDKYGTQRVISFLRQMVEHHGFYRITDMQWVSFERIQFVGACNPPTDPGRKPLSHRFLRHVPVVYVDYPGETSLKQIYSTFNRAMLRMLPSLRGYADTLTNAMVEFFLKTQERFTHDMQPHYIYSPREMTRWVRGIHEALKPLESLSVEGLVRIWAHEALRLFQDRLVEEDERHWTDDNINEVALKHFPNINKEEALKRPILYSNWLSKDYSAVTQEELRDYVKARLKVFYEEELDVPLVLFNQVLDHVLRIDRVFRQPQGHLLLIGVSGAGKTTLSRFVSWINGLSVFQVKVHNKYTAEDFDEDLRNVLRRSGCKGEKITFIMDESNVMDSSFLERMNTLLANGEVPGLFEGDELTTLMTQCKEGAIREGLMIDSQEELYKWFTQQICRNLHVVFTMNPSADGLKDKASTSPALFNRCVLNWFGDWSLEAYFQVGKEFTNRLDLERTDYKVPDTLPCIAEGLLPQNPIYRDVVVNALVFVHQTMHQANVRVQKRGGRTAAITPRHYLDLIAHYMKLSAEKRADLEEQQLHLNNGLKKIEQTVDQVEVMQRSLTKKRQELENMNEAANAKLKQMVQDQQEAEQKKTTGQALKEELAKQEQFVNEKQKTVKQELDQVEPTVNEAKQAVQNIRKKDIQEIKAMKNPPNAVKMAVESICLLLGEKTTDWQSILKVIIKDTFVTSIL-NFNTDDVSDNTRETMKKKYLSNPDYNFEKVNKASNACGPMVKWVLAQISYADILKRVEPLRNELTELSDAAEQNRKKSQETEDLIAQLEKSIAKYTEEYATLISQAQTIKSDLASVESKVGRSVALLGSLSSERTRWDSGSETFKAQMATINGDCLLSSAFMAYGGYFDQHMRTSLFNTWCHHLSEADILFRSDLARVEYLSNPDDRLRWQANSLPADDLCVENAIILRRYNRYPLIIDPSGQATTFLLNEYKEKKITKTSFLDDSFRKTLESALRFGTPLLVQDVESYDPILNPVLNREVRRTGGRTLITLGDQDIDLSPTFTIFLSTRDPSVEFAPDICSRVTFVNFTVTRSSLQNQCLNAVLKIERPDIDQKRSDLLKAQGEFQLKLRHLEKDLLQSLNEAQGNLLENDKIIARLETLKREAADVAKKVEETDVVMQEVESVSTEYVPLAQSCSNIYFTLEAMNQIHFLYQYSLQLMLDIFSSVLINNPELTNVKAASDRLKIITKNLFQVTYNRLARGMLHEDQITFATILARIFLKGSTPIGFLENEFQHFLRSQEATITSSDSNKQDNLGLTLHQDQIDSVKRLK-KLKVFAKIEEKVKSTKDIKNWTLTVTPESNVPELWVDDNNYNDEKLSKIAKGMYNLLIIQAIRPDRLLASTQKFIASVLGDTFTESVRGTLDLASIVEVEVTACVPILLCAVQGYDPSGRVEDLASEQGKQLTGIAIGSAEGFSQAEKAINSAAKTGKWVMLKNVHLATSWLVSLEKKIHSLQAHPNFRLFLTMEITPKLPVNLLRAGRVLVFEPPPGIKANLLRTLSSINNQRMSKEPVERSRLYFLLAWLNAIVQERLRYVPLGYSKKYEFGESDFKCALDTIDTWVDGAAMGRTNLPPEKIPWVALQTLLGSCIYGGKIDNAFDQRLLNSFLGYLFTEKCFDHNFALVSDADDGS----NIAFPESTKHTDILQWVHKLPDLQTPSWLGLPNSAEKVLLTNLGQSLIGNILKMQQSLEDDEELVVGQSKTKRTIEVG---DGRPAWMRQLYQSTQTWLQILPKSVTPLQRTIENIKDPMYRCFEREVNSGCNLLASVRKDLEDVAEVCKGAKKPTNHHRSMMADLAKGIIPKMWIRYAIPPGLTVIQWIQDFADRIKQLLHISDTAAKSGVIALRSIQVWLGGLFMAEAYITATRQSVAQNNKWALEELFLDVELGEG--KVDSNTCV--ITGLRLMGSEIVDPRTLKLSTLIYKDIDICRLKWIRVEKSQQLEGSSAKDKVCLPIYLNAARSTVLFT--LYFSTTDSSYDFYKRGVAI 14048 L +P N++ + KF++D QV L +Q+ + E E + + ++ISN+V+F +++ + IK V+EADK+I SQL+++++ DG P+ET+H+ + L PYFKSY+K+ G+ M PSVEKK+AELE+GLLHLQQNI+IPEITLT H V ++I++ +N++A+V+DF DK ED+ FLN LQ GVNRWI EI+KVTKLNRDP +GTALQEISFWLNLE +L +IQEKRES EVALTL ILK KRFHAT SFDTDT L A V DYN LMKDFPINDLLSA++L+KI A+QQIF+HL+KVR TKYP+ R +KL+EA+SRDL+ QL+KV+ LM +P+DEFE++ C ++FS W+DEYDK+Q LLRDI KKKR+E K W+++ HKKLQTR+E+++KFR QHEQLR VI+RVL+P K + D G+ T P ++AD ++I+EVN AYE VK +DCLD KE ++ W+AA+KRYEE+IDRVE+RI +HLRD LG +KNANEMFR FSRFNALFVRPHIRGAI EYQTQLIQRVKDDIEALH KFKVQY S +C++S VRDLPPV+GSIIW RQI QL Y+KRVEDVLGK W HIEGQKLKADG+SF+ KL+ S++F EW++KV E++ G IF +ESTR+ + + VL+L+VNFLP++ITLAKEVRN++ LGFR PL+IVNKAH ANQ+YP+AISLIESVRTYE T K+ + S+ L AGLRKDV + EG+ + WESY+LD YV +L+E V FQEKVDDL++V +++D +V++LETC Y+ TF EIL +IQ AVD++SL Q+SNL+ WV+ LD VE++L +RL+AG+ W + L G +E + + H+LGG PQI+ +HE+RITNQQM+LYPSIE A I+ Q +WQ I+ + R+ +RYQVGLE +TY+ LL+ LP G+ LENAY A+ + + YV W YQSLWDLQ D L+ + +D +W+ L +IK R FD ++T++ +GP++I + KVQ+KV++KYD+WHKE L KFG +G MT+ +++V ++R +LE QSI++ T+++V+FITY Q++K+ M W+KQ E R Q IL R RFQFPN WL +NI+GEWSAF EI++RK I +QVASLQ KI EDK VE++T + L +WEK KP G + P++A+ +QI E K++RLKEER+NV KAKEALEL E V S E++ AL EL DL+ VW+EL +W +I + +E PWLSVQPRKLRQ +E + AQLKELP + Y S+E+V+ L++ Y+KVN IVELKS+A+KERHW+ L ++L V+W L++L LG+VWD++L KNE I+++++ +AQGE ALEE+L+Q+ E W+NY L+L NYQ+K +II+GWDDLFNKVKEHIN+V +MK SPY+K FEEEA WE++LN+INALFDVWIDVQRRW+YL+GIF+GSADIK LLPVE+ RFQS+S+EFLGLMKKV KSP V DVLNI VQR LERLADLLGKIQK+LGEYLER+R+SFPRFYFVGDEDLLEIIGNSK++ +LQKHFKKMFAGV +I+L+E+ VILG+ S+EGEE+ F++PVS +EHP+IN+WL+ +EK+MR +LA L AV++I +R + ID +M W DKYQAQIVVLAAQI WSE VE++L ++ + V STLN+LAD+VL EQPP+RRRKLEHLI E+VH+R V R L N+GV+S K+F W+ +MRFYFDP+QT+ L QL+IH+ANA+F YGFEYLGV DRLVQTPLTDRCYLTMTQALE+RLGGSPFGPAGTGKTESVK+LGNQLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLSA SQQIQ IQEAL+ M S K+SI VEL+GKQV V+PDMAIFITMNPGYAGRSNLPDNLKKLFRSLAMT PDRQLIA+VML+SQGFR+AE LA K+VPFFKLCDEQLS QSHYDFGLRALKSVL+SAGNVKRDRI + KE++ RG+E I+E ++AE LPEQEILIQSV ETMVPKL+A+DIPLL+SLL+DVFP V Y +AEMK L+EE+RKV + +LV DE A G WV+KVLQLYQI+ ++HGLMMVGPSGSGK+ A + LL+ALE +G+EGVAH+IDPK+ISK++LYG +DPNTREWTDGLFTHILR+IID+VRGE NKRQWI+FDGDVDPEWVENLNSVLDDNKLLTLPNGERL++PPNVR+MFEVQDLK+ATLATVSRCGMVWFSE+VL+T MI ++L+ L+ + + +G+EDF G D + SP +Q+Q ++ +L PFF+ DG++ + L+Y+ EHIMDFTRLRAL+SLFSM+ Q+ RN++ +N H DFP + +Q+E+Y+ K+L+ SV+WS +GD+KLKVR L ++++++TV LP G IID+EVN+ G WV WSNKVP IEVETHK+ + D+VVPT+DTVRHE+LLYTWLAEH+P++LCGPPGSGKTMTLFSALR LPDMEVVGLNFSSATTPEL+LKTFD YCEYRKTPNG+VL+P Q+ KWL+ FCDEINLPDMD YGTQRVISFLRQ+VEH GFYR +D WVS ERIQFVGACNPPTDPGRKPLSHRFLRHVP++YVDYPGETSLKQIY TF+RAMLR++P+LRGYA+ LTNAMVEF+L +Q+RFT DMQPHY+YSPREMTRWVRGI EA++PL+SL VEGLVR+WAHEALRLFQDRLV++ ER WT++NI+ V KHFP IN+EEAL+RPILYSNWLSKDY V +EELR+YV ARLKVFYEEELDVPLVLF++VLDHVLRIDR+FRQPQGHLLLIGVSGAGKTTLSRFV+W+NGLS+FQ+KVHNKYT+EDFDEDLR VLRRSGCK EKI FI+DESNV+DS FLERMNTLLANGEVPGLFEGDE TTLMTQCKEGA REGLM+DS +ELYKWFTQQ+ RNLHVVFTMNPS DGLKD+A+TSPALFNRCVLNWFGDWS A FQVGKEFT R+DLE+ ++ PD P + L+P NP +RD V+N+ V+VHQT+HQAN R+ KRGGRT A+TPRHYLD I H++KL EKR+DLEEQQLHLN GL KI +TV+QVE MQ+SL K+QEL+ NEAANAKLKQM QDQQEAE+KK Q ++ LA Q + EK+K V +L QVEP V +A+ AV++IRK+ + E++ M NPP+ VK+A+ESICLLLGE TDW+SI VI+++ F+ SI+ NF T++++D+ RE MK KYLSNPDYNFEKVN+AS ACGPMVKW +AQI YAD+LKRVEPLR EL L + A+ N ++ET+DL+ QLE+SIA Y EEYA LISQAQ IK+DL +V++KV RS+ALL SL+ ER RW+S SETFK+QM+TI GD LLS+AF+AYGGYFDQH R +LF TW HL A I +R+D+AR EYLSNPD+RLRWQAN+LP DDLC ENAI+L+R+NRYPLIIDPSGQATTFLLNEY KKITKTSFLDDSFRK LESALRFG PLLVQDVE+YDPILNPVLNRE+RRTGGR LITLGDQDIDLSP+F IFLSTRDP+VEF PDICSRVTFVNFTVTRSSLQ+QCLN VLK ERPDID+KRSDLLK QGEF+L+LR LEK LLQ+LN+A+G +L++D +I LETLK+EA D+ +KV+ETD V+ E+E+VS +Y+PL+ +CSNIYFT++++NQ+HFLYQYSL++ LDIFS+VL NNP+L S+RL I+T++LFQV Y R+ARGM+H D++TFA ++ +I LKG++ L+ EF FLRS+E + +N GL+ +QI+SV RL +L +F K+ EKV+S ++ W +PE VP+LW + + LS IA ++ LL+IQA RPDR++A+ + +VLG+ F + LD S+V+ ++ P LLC+V G+D SGRV+DLA+EQ KQ++ IAIGSAEGF+QAE+AIN A KTG+WV+LKNVHLA WLV LEKK+HSLQ H FRLFLTMEI PK+PVNLLRAGR+ VFEPPPGI+ANLLRT S++ RM K P ER+RLYFLLAW +AIVQERLRYVPLG++KKYEF ESD + A DT+DTW+D AMGRTNLPPEK+PW AL TLL IYGGKIDN FDQRLL SFL LFT + F+ +FALV++ D S +I P+ T+ L+W+ L D QTPSWLGLPN+AEKVLLT G L+ +LKMQQ LEDD+EL VG DGRP+WM+ L+ S WL++LPK++ L+RT+ENIKDP+YR FEREV SG LL +V DL+DV +C+G KK TNHHRSM+++L +GIIPK W RY +P G TVIQWI DF++R++QL +S +++G L+ VWLGGL EAYITATRQ VAQ N W+LEEL LDV + + K D C +TGL+L G++ + L L++ I D+ + LKWI++ ++ K+ LP+YLN+ R+ +LFT L + S+ FY+RGVA+ Sbjct: 52 LDDPVNQDTIRKFLSDPQVQALYVQRNCIKEDDSEQPAEGEDEKEQVTYQISNDVHFTNSRMASLACIKRGLVVEADKSIHSQLRLINFSDGSPYETLHAFISKSLAPYFKSYVKESGRADRDGDK-MAPSVEKKLAELEMGLLHLQQNIDIPEITLTAHQTVNNVIRKCAEENRKAKVADFGDKVEDSSFLNLLQNGVNRWIAEIKKVTKLNRDPGSGTALQEISFWLNLERALYRIQEKRESPEVALTLDILKHGKRFHATVSFDTDTGLKQALATVADYNPLMKDFPINDLLSATELEKIRPAVQQIFAHLRKVRNTKYPIQRCLKLIEAISRDLSQQLLKVLGTRRLMHIPFDEFERVMNQCFEIFSCWDDEYDKLQGLLRDIVKKKRDEHLKMVWRVSPAHKKLQTRMEHMRKFRRQHEQLRTVILRVLRPT------------KPAVGDDGNVVETKQPYSLDAADANAIEEVNLAYENVKEVDCLDITKEGSEAWEAAVKRYEEKIDRVETRITAHLRDQLGTAKNANEMFRIFSRFNALFVRPHIRGAIREYQTQLIQRVKDDIEALHEKFKVQYPQSKSCRLSSVRDLPPVAGSIIWARQIDNQLTMYLKRVEDVLGKGWETHIEGQKLKADGDSFRAKLSISDVFHEWARKVQERNFGSTGRIFTIESTRSRIG-------RGNVLRLRVNFLPEIITLAKEVRNIKNLGFRVPLTIVNKAHQANQIYPYAISLIESVRTYERTLEKLNNRSLAQNSVFKIEDRASIVPLVAGLRKDVLNLVSEGIGLIWESYKLDPYVIRLSECVTQFQEKVDDLLVVEEQLDVDVRSLETCPYSAATFVEILSKIQHAVDDLSLRQYSNLSVWVTRLDEEVEKKLALRLQAGIQAWTEALTGNKKEVDTSMDTD---APAQPTHKLGGDPQIQNAVHEIRITNQQMYLYPSIEEARFQIMQQFFAWQAIVTSQVRLQSTRYQVGLEKHVS--QTYRNLLTKLP-EGKILENAYGAIEQKVSEVRNYVDEWLRYQSLWDLQADMLYGRLGEDVNLWIKCLNDIKQSRTTFDTSDTRRAYGPIIIDYAKVQAKVTLKYDSWHKEALGKFGTLLGTEMTSFHSKVSKSRTDLEMQSIEAASTSDAVSFITYVQSLKKDMIAWDKQVEVFREAQRILERQRFQFPNTWLHVDNIEGEWSAFNEIIKRKDTAIQTQVASLQAKIVAEDKAVETRTVDFLNDWEKTKPTGGKIRPDDALQQLQIFESKYSRLKEERDNVVKAKEALELQESAVPNNSAERMNVALEELQDLRGVWSELSKVWTQIDETREKPWLSVQPRKLRQQLEAMMAQLKELPARLRMYESYEYVKKLIQSYIKVNMLIVELKSDALKERHWKQLTKQLRVNWVLSDLSLGQVWDVNLQKNEGIVKDIILVAQGEMALEEFLKQVRESWQNYELDLINYQNKCRIIRGWDDLFNKVKEHINSVAAMKLSPYYKVFEEEALTWEEKLNRINALFDVWIDVQRRWVYLEGIFSGSADIKTLLPVETSRFQSISSEFLGLMKKVTKSPKVMDVLNIPAVQRSLERLADLLGKIQKALGEYLERERTSFPRFYFVGDEDLLEIIGNSKNIARLQKHFKKMFAGVAAILLNEENNVILGISSREGEEVHFMNPVSTVEHPKINEWLSLVEKQMRFTLASLLAQAVQDIKQFR-DGKIDPQAYMEWCDKYQAQIVVLAAQILWSEDVESALQQASENNQSKPMQRVLGNVESTLNVLADSVLQEQPPLRRRKLEHLINEFVHKRTVTRRLLNNGVTSPKSFQWLCEMRFYFDPRQTEVLQQLTIHMANARFFYGFEYLGVQDRLVQTPLTDRCYLTMTQALESRLGGSPFGPAGTGKTESVKALGNQLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLSACSQQIQTIQEALKYEMDSNKESITVELVGKQVRVSPDMAIFITMNPGYAGRSNLPDNLKKLFRSLAMTTPDRQLIAEVMLFSQGFRSAEKLACKIVPFFKLCDEQLSNQSHYDFGLRALKSVLISAGNVKRDRIMKIKEQMKQRGDENIDEASVAENLPEQEILIQSVCETMVPKLVAEDIPLLFSLLSDVFPNVGYTRAEMKGLKEEIRKVCQEDYLVCGEGDEQGAAWMEKGLGSTWVDKVLQLYQISNLNHGLMMVGPSGSGKSTAWKTLLKALERFEGVEGVAHVIDPKAISKEALYGVLDPNTREWTDGLFTHILRKIIDNVRGEINKRQWIIFDGDVDPEWVENLNSVLDDNKLLTLPNGERLSLPPNVRVMFEVQDLKFATLATVSRCGMVWFSEDVLSTEMIFENYLSRLRSIPLEDGDEDFV---GVIKPAKDKEEEVSPSLQVQRDIALLLLPFFSADGIVVRTLEYAMDQEHIMDFTRLRALSSLFSMLNQAARNVLTFNAQHPDFPCSADQLEHYIPKALVYSVLWSFAGDAKLKVRIDLGDFVRSVTTVPLPGAAGAP-IIDYEVNMSGDWVPWSNKVPVIEVETHKVASPDIVVPTLDTVRHESLLYTWLAEHKPLVLCGPPGSGKTMTLFSALRALPDMEVVGLNFSSATTPELLLKTFDHYCEYRKTPNGVVLSPVQIGKWLVLFCDEINLPDMDSYGTQRVISFLRQLVEHKGFYRASDQAWVSLERIQFVGACNPPTDPGRKPLSHRFLRHVPIIYVDYPGETSLKQIYGTFSRAMLRLMPALRGYAEPLTNAMVEFYLASQDRFTQDMQPHYVYSPREMTRWVRGICEAIRPLDSLPVEGLVRLWAHEALRLFQDRLVDDSERRWTNENIDLVGQKHFPGINQEEALQRPILYSNWLSKDYMPVNREELREYVHARLKVFYEEELDVPLVLFDEVLDHVLRIDRIFRQPQGHLLLIGVSGAGKTTLSRFVAWMNGLSIFQIKVHNKYTSEDFDEDLRCVLRRSGCKDEKIAFILDESNVLDSGFLERMNTLLANGEVPGLFEGDEYTTLMTQCKEGAQREGLMLDSSDELYKWFTQQVMRNLHVVFTMNPSTDGLKDRAATSPALFNRCVLNWFGDWSDSALFQVGKEFTTRVDLEKPNWHAPDFFPSVCP-LVPANPTHRDAVINSCVYVHQTLHQANARLAKRGGRTMAVTPRHYLDFIHHFVKLYNEKRSDLEEQQLHLNVGLNKIAETVEQVEEMQKSLAVKKQELQAKNEAANAKLKQMFQDQQEAEKKKIQSQEIQIRLADQTVKIEEKRKYVMADLAQVEPAVIDAQAAVKSIRKQQLVEVRTMANPPSVVKLALESICLLLGENATDWKSIRAVIMRENFINSIVSNFGTENITDDVREKMKSKYLSNPDYNFEKVNRASMACGPMVKWAIAQIEYADMLKRVEPLREELRSLEEQADVNLASAKETKDLVEQLERSIAAYKEEYAQLISQAQAIKTDLENVQAKVDRSIALLKSLNIERERWESTSETFKSQMSTIIGDVLLSAAFIAYGGYFDQHYRLNLFTTWSQHLQAASIQYRADIARTEYLSNPDERLRWQANALPTDDLCTENAIMLKRFNRYPLIIDPSGQATTFLLNEYAGKKITKTSFLDDSFRKNLESALRFGNPLLVQDVENYDPILNPVLNRELRRTGGRVLITLGDQDIDLSPSFVIFLSTRDPTVEFPPDICSRVTFVNFTVTRSSLQSQCLNQVLKAERPDIDEKRSDLLKLQGEFRLRLRQLEKSLLQALNDAKGKILDDDSVITTLETLKKEAYDINQKVDETDKVIAEIETVSQQYLPLSVACSNIYFTMDSLNQVHFLYQYSLKMFLDIFSTVLYNNPKLEGRTDHSERLGIVTRDLFQVCYERVARGMIHIDRLTFALLMCKIHLKGTSESN-LDAEFNFFLRSREGLL----ANPTPVEGLS--AEQIESVNRLALRLPIFRKLLEKVRSIPELGAWLQQSSPEQVVPQLWDE-----SKALSPIASSVHQLLLIQAFRPDRVIAAAHNVVNTVLGEDFMPNAEQELDFTSVVDKQLNCNTPALLCSVPGFDASGRVDDLAAEQNKQISSIAIGSAEGFNQAERAINMACKTGRWVLLKNVHLAPQWLVQLEKKMHSLQPHSGFRLFLTMEINPKVPVNLLRAGRIFVFEPPPGIRANLLRTFSTVPAARMMKTPSERARLYFLLAWFHAIVQERLRYVPLGWAKKYEFNESDLRVACDTLDTWIDTTAMGRTNLPPEKVPWDALVTLLSQSIYGGKIDNDFDQRLLTSFLKKLFTARSFEADFALVANVDGASGGLRHITMPDGTRRDHFLKWIENLTDRQTPSWLGLPNNAEKVLLTTRGTDLVSKLLKMQQ-LEDDDELAYSVEDQSEQSAVGRGEDGRPSWMKTLHNSATAWLELLPKNLQVLKRTVENIKDPLYRYFEREVTSGSRLLQTVILDLQDVVLICQGEKKQTNHHRSMLSELVRGIIPKGWKRYTVPAGCTVIQWITDFSNRVQQLQKVSQLVSQAGAKELQGFPVWLGGLLNPEAYITATRQCVAQANSWSLEELALDVTITDAGLKNDQKDCCFGVTGLKLQGAQCKNNELL-LASTIMMDLPVTILKWIKISSEPRI------SKLTLPVYLNSTRTELLFTVDLAVAAGQESHSFYERGVAV 4654
BLAST of Cytoplasmic dynein 1 heavy chain 1 vs. Ensembl Zebrafish
Match: dync1h1 (dynein, cytoplasmic 1, heavy chain 1 [Source:ZFIN;Acc:ZDB-GENE-030131-7050]) HSP 1 Score: 1991.85 bits (5159), Expect = 0.000e+0 Identity = 1004/1748 (57.44%), Postives = 1317/1748 (75.34%), Query Frame = 3 Query: 186 PCMLNDDESKSRKDYELFLSEPQNEECLTKFINDNQVTTLTIQQTK-RXXXXXXXXXXXXKISNEVNFESN---KSQTSIFIKNNQVIEADKTISSQLQVLSYCDGPPFETMHSLVCYGLLPYFXXXXXXXXXXXXXXXXXMVPSVEKKIAELEIGLLHLQQNIEIPEITLTPHPYVAHIIQEKLLQNKEARVSDFEDKFEDTQFLNQLQAGVNRWIKEIQKVTKLNRDPSTGTALQEISFWLNLEHSLDKIQEKRESLEVALTLAILKQAKRFHATTSFDTDTALSSAKIQVKDYNQLMKDFPINDLLSASQLDKISEALQQIFSHLKKVRATKYPVNRIIKLMEALSRDLTTQLMKVISNMHLMSMPYDEFEKIFTACQQVFSTWEDEYDKMQNLLRDIAKKKREEFTKFAWKMNATHKKLQTRLENIKKFRYQHEQLRQVIVRVLKPVTKVVPS---VEAGVPKDQITDKGDKSSTFLPESADTSSIDEVNAAYEIVKVIDCLDFAKEENDEWDAAIKRYEERIDRVESRIASHLRDLLGQSKNANEMFRYFSRFNALFVRPHIRGAIGEYQTQLIQRVKDDIEALHNKFKVQYASSTACKMSKVRDLPPVSGSIIWVRQILRQLNAYMKRVEDVLGKDWAQHIEGQKLKADGESFKLKLNTSELFEEWSKKVAEKSLSVAGSIFNVESTRTVVTVRDREPQKITVLKLKVNFLPDVITLAKEVRNMRALGFRTPLSIVNKAHSANQLYPFAISLIESVRTYESTCSKIEEHKMQNISLLTAGLRKDVQLCIHEGVQITWESYRLDQYVQKLAELVFSFQEKVDDLVIVIKEIDFNVKALETCSYNKQTFEEILIRIQEAVDNMSLHQFSNLAQWVSNLDSLVEQRLIVRLEAGLLEWIKVLKGXXXXXXXXXXXXXXXVNSMAKHRLGGKPQIKKLIHELRITNQQMHLYPSIEVATQDILYQMSSWQNIILNLSRIVHSRYQVGLETE-SDNQKTYKKLLSSLPNSGESLENAYAAVHNILRDANEYVKTWTNYQSLWDLQGDQLFSLIADDNTVWMNVLEEIKSMRKHFDVAETQKEFGPLVIAFGKVQSKVSMKYDNWHKEVLTKFGQNMGKMMTTLYNEVQRARNELEQQSIDSGGTNESVNFITYTQNIKRKMNTWEKQAEACRAGQNILCRDRFQFPNDWLDSENIQGEWSAFKEIMRRKQETISSQVASLQMKITEEDKIVESKTTEVLGNWEKDKPIAGDLTPEEAVNIIQILEGKFNRLKEERENVQKAKEALELTEIGVKPISEEKVTN-ALSELHDLKNVWNELKSIWEKIRDMKETPWLSVQPRKLRQDIENLTAQLKELPNSFKQYASFEHVRTLLKMYMKVNASIVELKSEAIKERHWRMLMRKLNVSWSLNELQLGKVWDIDLVKNEEIIREVLAIAQGEKALEEYLRQITEVWKNYVLELTNYQSKSKIIKGWDDLFNKVKEHINNVTSMKASPYFKQFEEEATAWEDRLNKINALFDVWIDVQRRWIYLDGIFAGSADIKVLLPVESQRFQSVSTEFLGLMKKVQKSPLVTDVLNIANVQRQLERLADLLGKIQKSLGEYLERQRSSFPRFYFVGDEDLLEIIGNSXXXXXXXXXXXXMFAGVHSIILSEDEKVILGMMSKEGEELRFISPVSIIEHPRINDWLTAMEKEMRVSLAKYLNVAVKEISGWRTESNIDKDKFMVWLDKYQAQIVVLAAQITWSEAVEAS 5402 P +L +D + E L E E + KF++D Q+ ++ ++++ +E+ E IS V+ + + KS + IK VI+ADK IS+Q++VL+ + P+ET+HS + + PYFKSYI++ GK M PSVEKKIAELE+GLLHLQQNIEIPEI+L HP ++++ ++ + ++ +V+DF DK ED FLNQLQ+GVNRWI+EIQKVTKL+RDP++GTALQEISFWLNLE +L++IQEKRES EV LTL ILK KRFHAT SFDTDT L A V DYN LMKDFP+NDLLSA++LDKI +AL IF+HL+K+R TKYP+ R ++L+EA+SRDL++QL+KV+ LM + Y+EFEK+ AC +VF TWEDEY+K+Q LLRDI K+KREE K W+++ H+KLQ RL+++++FR QHEQLR VIVRVL+P VP E+ P D K + L ++AD ++I+EVN AYE VK +D LD +KE + W+AA+KRY+ERIDRVE+RI + LRD LG +KNANEMFR FSRFNALFVRPHIRGAI EYQTQLIQRVKDDIE+LH+KFKVQY S +CKMS VRDLPPVSGSIIW +QI RQL AYMKRVEDVLGK W H+EG KLK DG+SF+ KLNT E+F++W++KV +++L V+G IF +E+TR R R TVLKLKVNFLP++ITL+KEVRN++ L FR PL+IVNKAH ANQLYPFAISLIESVRTYE TC K+EE +ISLL AGL+K+VQ I EG+ + WESY+LD YVQ+LAE VF+FQEKVDDL+++ ++ID V++LETC Y + F EIL RIQ+AVD+++LH +SNL WV+ LD +E+ L VRL+AGL W +VL+G+ + + D DT+ H+ GG+P+IK +IHELRITNQ ++L P IE + +M +W+ IL+L RI RYQVG+ E S+ +K Y+ L+ +P+ +LE AY AV + + +YVK W YQ LWD+Q + +++ + +D W +L +I+ R FD AET+KEFGP++I +GKVQSKV++KYD+WHKEVL++FGQ +G M ++++ ++R ELEQ S+D+ T+++V FITY Q +KRK+ +EKQ + R GQ +L + RFQFP WL +NI+GEW AF +IM+RK I QVA+LQMKI +ED+ VE++TT++L +WEK KP+AG L PEEA+ + I EGKF RLK++RE KAKEALELT+ G+ SEE+V AL EL DLK VW+EL +WE+I MKE PW+SVQPRKLRQ ++ L QLK P +QYAS+E+V+ LLK YMKVN ++ELKSEA+K+RHW+ LM++L+V+W L+EL LG++WD+DL KNE ++++VL +AQGE ALEE+L+Q+ L+L NYQ+K ++I+GWDDLFNKVKEHIN+V++MK SPY+K FEE+A +WED+LN+I ALFDVWIDVQRRW+YL+GIF GSADIK LLPVE+QRFQS+STEFL LMKKV KSPLV DVLNI VQR LERLADLLGKIQK+LGEYLER+RSSFPRFYFVGDEDLLEIIGNSK++ KLQKHFKKMFAGV SI+L+ED +LG+ S+EGEE+ + + VSI EHP+IN+WLT +E+EMRV+LAK L +V E+ G+ + ID ++ W+D+YQAQ+VVL+ QI WSE VE++ Sbjct: 38 PLLL-EDGADPPASLESALEEKSALEQMRKFLSDPQIHSILVERSALKEDVGDEGEEERECISYSVSIDIHYGLKSNSLALIKRTGVIDADKPISTQVRVLTLSEDSPYETLHSFISNAVAPYFKSYIRESGKADRDGDK-MAPSVEKKIAELEMGLLHLQQNIEIPEISLLIHPIISNVAKQCYERGEKPKVTDFGDKVEDPTFLNQLQSGVNRWIREIQKVTKLDRDPASGTALQEISFWLNLERALNRIQEKRESPEVLLTLDILKHGKRFHATVSFDTDTGLKQAVETVNDYNPLMKDFPLNDLLSATELDKIRQALVAIFTHLRKIRNTKYPIQRALRLVEAISRDLSSQLLKVLGTRKLMHVAYEEFEKVMVACFEVFQTWEDEYEKLQVLLRDIVKRKREENLKMVWRLSPAHRKLQARLDHMRRFRRQHEQLRAVIVRVLRPQVSAVPQHAQGESAEPADL------KVAEVLFDAADANAIEEVNLAYENVKEVDGLDVSKEGMEAWEAAMKRYDERIDRVETRITARLRDQLGTAKNANEMFRIFSRFNALFVRPHIRGAIREYQTQLIQRVKDDIESLHDKFKVQYPQSQSCKMSHVRDLPPVSGSIIWAKQIDRQLTAYMKRVEDVLGKGWENHVEGLKLKQDGDSFRAKLNTQEIFDDWARKVQQRNLGVSGRIFTIENTRA----RGRTG---TVLKLKVNFLPEIITLSKEVRNLKWLSFRVPLAIVNKAHQANQLYPFAISLIESVRTYERTCEKVEERV--SISLLVAGLKKEVQALITEGISLVWESYKLDPYVQRLAETVFNFQEKVDDLLLIEEKIDLEVRSLETCMYEHKMFTEILNRIQKAVDDLNLHSYSNLPIWVNKLDIEIERILGVRLQAGLKAWTQVLRGQMEDKADVDMDTEA---PQVSHKPGGEPRIKNIIHELRITNQVIYLNPPIEDCRYRLYQEMFAWKMNILSLPRIQSQRYQVGVHYELSEEEKFYRNALTRMPDGPSALEEAYNAVKENVSEVEQYVKVWLQYQCLWDMQPENIYNRLEEDLNKWQALLVQIRKARGTFDNAETRKEFGPVIIDYGKVQSKVNLKYDSWHKEVLSRFGQMLGNNMQDFHSQISKSRQELEQHSVDTASTSDAVTFITYVQTLKRKIKQFEKQVDLFRNGQRLLEKQRFQFPPSWLYIDNIEGEWGAFSDIMKRKDTAIQQQVANLQMKIVQEDRAVENRTTDLLADWEKTKPVAGSLRPEEALQSLTIYEGKFGRLKDDREKCAKAKEALELTDTGLPSSSEERVQQVALEELQDLKGVWSELSKVWEQIDQMKEQPWVSVQPRKLRQSLDGLLNQLKNFPARLRQYASYEYVQRLLKGYMKVNMLVIELKSEALKDRHWKQLMKRLHVNWVLSELSLGQIWDVDLQKNEMVVKDVLLVAQGEMALEEFLKQVLHTHTXXELDLVNYQNKCRLIRGWDDLFNKVKEHINSVSAMKLSPYYKVFEEDALSWEDKLNRIMALFDVWIDVQRRWVYLEGIFTGSADIKHLLPVETQRFQSISTEFLALMKKVTKSPLVMDVLNIQGVQRSLERLADLLGKIQKALGEYLERERSSFPRFYFVGDEDLLEIIGNSKNVAKLQKHFKKMFAGVSSILLNEDNTEVLGISSREGEEVLYKTAVSITEHPKINEWLTLVEREMRVTLAKLLAESVTEVGGFNKGTGIDLTTYISWIDRYQAQLVVLSTQIDWSENVESA 1765
BLAST of Cytoplasmic dynein 1 heavy chain 1 vs. Ensembl Zebrafish
Match: dnah2 (dynein, axonemal, heavy chain 2 [Source:ZFIN;Acc:ZDB-GENE-130530-910]) HSP 1 Score: 1425.99 bits (3690), Expect = 0.000e+0 Identity = 1034/3712 (27.86%), Postives = 1846/3712 (49.73%), Query Frame = 3 Query: 3255 YVKTWTNYQSLWDLQGDQLFSLIADDNTVWMNVLEEIKSMRKHFDVAE-TQKEFGPLVIAFGKVQ-SKVSMKYDNWHKEVLTKFGQNMGKMMTT----LYNEVQRARNELEQQSIDSGGTNESVNFITYTQNIKRKMNTWEKQAEACRAGQNILCRDRFQFPNDWLDS-ENIQGEWSAFKEIMRRKQETISSQVASLQMKITEEDKIVESKTTEVLGNWEKDKPIAGDLTPEEAVNIIQILEGKFNRLKEERENVQKAKEALELTEIGVKPI-SEEKVTNALSELHDLKNVWNELKSIWEKIRDMKETPWLSVQPRKLRQDIENLTAQLKELPNSFK--QYASFEHVRTLLKMYMKVNASIVELKSEAIKERHWRMLMRKLNVSW--SLNELQLGKVWDIDLVKNEEIIREVLAIAQGEKALEEYLRQITEVWKNYVLELTNYQSKSK-IIKGWDDLFNKVKEHINNVTSMKASPYFKQFEEEATAWEDRLNKINALFDVWIDVQRRWIYLDGIFAGSADIKVLLPVESQRFQSVSTEFLGLMKKVQKSPLVTDVLNIANVQRQLERLADL---LGKIQKSLGEYLERQRSSFPRFYFVGDEDLLEIIGNSXXXXXXXXXXXXMFAGVHSIILSE----DEKVILGMMSKEGEELRFISPVSIIEHPRINDWLTAMEKEMRVSLAKYL---NVAVKEISGWRTESNIDKDKFMVWLDKYQAQIVVLAAQITWSEAVEASL------ASGVSLESTMTVVHSTLNMLADTVLYEQPPVRRRKLEHLIIEYVHQRDVLRALHNDGVSSNKNFDWMSQMRFYFDPKQTDPLHQLSIHVANAKFHYGFEYLGVCDRLVQTPLTDRCYLTMTQALEARLGGSPFGPAGTGKTESVKSLGNQLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLSAVSQQIQGIQEALRELMVSKKDSINVELLGKQVHVNPDMAIFITMNPGYAGRSNLPDNLKKLFRSLAMTQPDRQLIAQVMLYSQGFRTAEVLAGKVVPFFKLCDEQLSPQSHYDFGLRALKSVLVSAGNVKRDRIKQEKEKIVARGEEINETAIAEQLPEQEILIQSVMETMVPKLIADDIPLLYSLLTDVFPGVEYRQAEMKRLRE----ELRKVSENKFLVYSDEPNTAGYLWVEKVLQLYQITTIHHGLMMVGPSGSGKTMACRVLLQALENI--DGIEGVAHI----IDPKSISKDSLYGYMDPNTREWTDGLFTHILRRIIDSVRGESNKRQWIVFDGDVDPEWVENLNSVLDDNKLLTLPNGERLAIPPNVRIMFEVQDLKYATLATVSRCGMVWFSEEVLTTGMILTHFLNELKKVQVMEGEEDFSVNQGDTGADADSKISSSPIIQLQTQVSSILAPFFTEDGLIAKCLDYSTT-LEHIMDFTRLRALTSLFSMIKQ--SIRNMIEYNQSHSDFPLNNEQIENYVAKSLISSVVWSMSGDSKLKVREQLSQYIKNISTVDLPTVGGIKN---IIDFEVNIQG-TWVAWSNKVPQIEVETHKITATDVVVPTMDTVRHEALLYTWLAEHRPVLLCGPPGSGKTMTLFSALRCLPDM--EVVGLNFSSATTPELMLKTFDQYCEYR----KTPNGIVLAPQQLNKWLIFFCDEINLPDMDKYGTQRVISFLRQMVEHHGFYRITDMQWVSFERIQFV-GACNPPTDPGRKPLSHRFLRHVPVVYVDYPGETSLKQIYSTF-NRAMLRMLPSLRGYADTLTNAMVEFFLKTQERF-THDMQPHYIYSPREMTRWVRGIHEALKPLESLSVEGLVRIWAHEALRLFQDRLVEEDERHWTDDNINEVALKHF--------PNINKEEALKRPILYSNWLSKDYSAVTQEELRDYVKARLKVFYEEELD--------VP--LVLFNQVLDHVLRIDRVFRQPQGHLLLIGVSGAGKTTLSRFVSWINGLSVFQVKVHNKYTAEDFDEDLRNVLRRSGCKGEKITFIMDESNVMDSSFLERMNTLLANGEVPGLFEGDELTTLMTQCKEGAIREGLMIDSQEELYKWFTQQICRNLHVVFTMNPSADGLKDKASTSPALFNRCVLNWFGDWSLEAYFQVGKEFTNRLDLERTDYKVPDTLPCIAEGLLPQNPIYRDVVVNALVFVHQTMHQANVRVQKRGGRTAAITPRHYLDLIAHYMKLSAEKRADLEEQQLHLNNGLKKIEQTVDQVEVMQRSLTKKRQELENMNEAANAKLKQMVQDQQEAEQKKTTGQALKEELAKQEQFVNEKQKTVKQELDQVEPTVNEAKQAVQNIRKKDIQEIKAMKNPPNAVKMAVESICLLLGEKTTDWQSILKVIIKDTFVTSILNFNTDDVSDNTRETMKKKYLSNPDYNFEKVNKASNACGPMVKWVLAQISYADILKRVEPLRNELTELSDAAEQNRKKSQETEDLIAQLEKSIAKYTEEYATLISQAQTIKSDLASVESKVGRSVALLGSLSSERTRWDSGSETFKAQMATINGDCLLSSAFMAYGGYFDQHMRTSLF-NTWCHHLSEADILFRSDLARVEYLSNPDDRLRWQANSLPADDLCVENAIILRRYNRYPLIIDPSGQATTFLLN-EYKEK-KITKTSFLDDSFRKTLESALRFGTPLLVQDV-ESYDPILNPVLNREVRRTGGRTLITLGDQDIDLSPTFTIFLSTRDPSVEFAPDICSRVTFVNFTVTRSSLQNQCLNAVLKIERPDIDQKRSDLLKAQGEFQLKLRHLEKDLLQSLNEAQGNLLENDKIIARLETLKREAADVAKKVEETDVVMQEVESVSTEYVPLAQSCSNIYFTLEAMNQIHFLYQYSLQLMLDIFSSVLINNPELTNVKAASDRLKIITKNLFQVTYNRLARGMLHEDQITFATILARIFLKGSTPIGFLENEFQHFLRSQEATITSSDSNKQDNLGLTLHQDQIDSVKRLKKLKVFAKIEEKVKS-TKDIKNWTLTVTPE-SNVPELWVDDNNYNDEKLSKIAKGMYNLLIIQAIRPDRLLASTQKFIASVLGDTFTESVRGTLDLASIVEVEVTACVPILLCAVQGYDPSGRVEDLA--SEQGKQLTGIAIGSAEGFSQAEKAINSAAKTGKWVMLKNVHLATSWLVSLEKKIHSLQ---AHPNFRLFLTMEITPKLPVNLLRAGRVLVFEPPPGIKANLLRTLSSINNQRM--SKEPVERSRLYFLLAWLNAIVQERLRYVPLGYSKKYEFGESDFKCALDTIDTWVDGAAMGRTNLPPEKIPWVALQTLLGSCIYGGKIDNAFDQRLLNSFLGYLFTEKCFDHNFALVSDADDGSNIAFPESTKHTDILQWVHKLPDLQTPSWLGLPNSAEKVLLTNLGQSLIGNILKMQQSLEDDEELVVGQSKTKRTIEVGDGRPAWMRQLYQSTQTWLQILPKSVTPLQRTIENIKD---PMYRCFEREVNSGCNLLASVRKDLEDVAEVCKGAKKPTNHHRSMMADLAKGIIPKMWIRYAIPPGLTVIQWIQDFADRIKQLLHISDTAAKSGVIALRSIQVWLGGLFMAEAYITATRQSVAQNNKWALEELFLDVELGEGKVDSNT--------CVITGLRLMG-------SEIVDPRTLKLSTLIYKDIDICRLKWIR---VEKSQQLEGSSAKDKVCLPIYL------NAARSTVLFTLYFSTTDSSYDFY-KRGVAI 14048 Y+KTW ++ +W+++ D N + +I ++ +VA QKE L + F + S + E +KF Q + M ++ L++ +Q L Q ES+ + + ++ +N E Q IL + L+ E + EW F++++ + +++ + + + KT L ++ + P +TP A+ + L + LKEE +N+ + + K I + EK + L ++ ++ W +L + W K S+Q + + + L +L +FK + + ++ ++ + K+ I +L++ A++ERHW + +++ ++ S + L K+ + L + E I ++ A E ++E+ L I + WK L++T ++ K ++G D++F ++++ ++ +KAS + K FE+E WE L+ + + ++ + VQR+W+YL+ IF DI+ L E+ F +V++ + +M+++ K + L + LE+L+++ L +IQKSL YLE +R FPRFYF+ ++DLLEI+G S++ + +Q H KK F + S+ +++ ++ GM S +GE + F PV ++E P + WL +E+ MR +L L ++A+K++ G R + W+ + Q+++ A+QI W+ V +L A +L+S S LN ++ + + R K+ L+ VH RDV+ L G FDW+ Q+R Y++ D + I N F YG+EYLG RLV TPLTDRCY+T+T AL GGSP GPAGTGKTE+VK LG LG +V+V NC E DF++MGR++ GL Q GAWGCFDEFNR+ +LS V+QQI I AL + N G+Q+++ IFITMNPGYAGR+ LPDNLK +FR ++M PD LIA++ L+++GF +VLA KV + L +QLS Q HYDFGLRAL S+L AG +R AR + ++E EIL+ S+ + + KL + D+PL ++ D+FP VE + +L+E ELR+ S + + ++ V KV+QLY+ H M+VG +GSGKT+ R L L + +G G I ++PK++S LYG + +T EWTDG+ + ++R + E +WIVFDG VD W+E++NSV+DDNK+LTL NGER+++P V ++FEV+DL A+ ATVSRCGMV+ L + ++ + +KV+ + +L F + I K L + T + ++ T L + SL + + + N ++ P ++E V I S++WS+ + R+++ +++ I G N I ++ V+ + TW ++ +K+P+ ++VPT+DTVR+ L+ ++ PVLL GP G+GKT S L+ L ++ + +N SS T+ + + + E R P G K ++ F D++N+P +D +G+Q + LR +++ GF+ Q + + + F+ G+ PP GR +S R ++ + +P E+ +K+IY T ++ + ++ LT A +E + RF + HY+++ R++++ +G+ A K + + + R+W HE R+F DRLV+ + ++E HF PN K+P L+ ++L + + E+L D+ KA LKV E +L+ VP LVLF +DHV R+ RV Q +G++LL+G+ G+G+ +L+R ++I +VFQV+V +Y ++F ED++ + R +G + + F+ +++ ++D SFLE +N +L++GEVP L++ DEL + + + A R+ ++++ + ++ + +++ NLH+V M+P D +++ PAL N ++WF +W +A +V + + L L D G+ + V + V VHQ++ Q + R++ R +TP +YL+L++ Y KL +EKR +L EQ L NGL KI+ T +VE M L + ++++ + L +VQ ++EA++++ A E++ +E + +++LD+ P + EA +A++++ KKD+ EIK+ PP V+ ++++ +L G + T W + + + F+ ++NF+ D++SD +T+ + Y + PD+ E + + S A + WV A Y I + VEP R L + + E + + ++ + + +Y ++Q + ++ +E K+ R+ L+ L+ ER RW + + M+ + GDCLL++AF++Y G F + R L + W + E ++ + +LS P W LP+D EN +I+ R NR+PL++DP GQA ++ N E+K+ K+ D F + LE+A++FG+P+L+Q+V E DP L P+LN+ + R GGR L+ LGD++I+ SP F +++T+ + + P+I S+ T VNF V L+ Q L V++ ERP++++++ L+ + KL+ LE ++L+ LNEA G+LL++ +++ L+T K A +VA+++E +++ ++++ Y P AQ S ++F L + I +YQ+SL +++F + ++P ++ +R+ + ++ Y RG+ ++ F+ + L+ S + +E+ FLR + + + L D++ L KL F ++ + +D +W PE + +P W +N+ N+ + +LI++++R DR+ F+ + LG F E LD+ ++V + T P++ G DP+ + LA S G++ +++G + A + I G WV L N HL+ SW+ L+K + LQ HP+FRL+L+ P+ P+ +L+ G + EPP G+K N+ R ++ + P+ +L F L + ++++ ER +++ LG++ Y F +SDF+ + + + ++D E+IPW AL+ L+ YGG + + +D+RLL +++ F D F VS + P + + ++ +LP L+ P G +A+ ++L +L +Q + + G S+ + +E+ + LQ +P + + T + +KD P+ +E+ LL ++R L ++ + KG ++ + +P +W + A P + W +D R++Q ++TA + WL G ++TA QS A+ N +++ L E V+ N +I GL L G S +V+ ++L +C + I VE ++L AK+ P Y ++ R + + + + YD + KRG A+ Sbjct: 1033 YLKTWDKHREIWEIEKDSFIQRYQRLNPTVTSFDADIA---RYTEVANNVQKEETLLSVQFVLLDCSPLKFSLLQHCNEWQSKFTQLLSLMASSKLKELHSFLQENAVRLSQPPQTLTDLGESLKLL---ETLQADLNKIESQIPPIHEQYAILTKYEVAVDPAVLELLEALNAEWVWFQQVVIDSDIMLKKHKDTMKSGLILSSEEFQKKTQTFLQSFSSNGPFGSSVTPHSALQQVSELRAQLEALKEEEQNICSGLNIFTIEQPASKDILALEKDVDYLQQVWEIARQWEDLWAEW------KGGHLASLQTEVMDNTAQTMFKTLHKLSRAFKDKHWEIVDSSKSRIEQFKKIIPLITDLRNSALRERHWNQIRQEVQQTFDPSSADFTLEKIVALGLDHHAESISDISGAASKELSIEQTLEGIMKTWKEMSLDITPHKDKGHHKLRGTDEVFQALEDNQVTLSVIKASRFVKAFEKEVDHWERCLSLVLEVIEMILTVQRQWMYLENIFLAD-DIRKQLVRETAEFDAVTSSWKIIMERLDKD---KNALRGTHHPGLLEKLSEMNTKLEEIQKSLDMYLETKRQIFPRFYFLSNDDLLEILGQSRNPEAVQPHLKKCFDNIKSLRINKVGTGNKSEASGMFSADGEFVDFTHPV-LLEGP-VEAWLCDVERTMRWTLKDSLRNCSMALKKMPGKRGK----------WVRDWPGQMLITASQIQWTTDVTRALMTSKERADKSALKSLKKKQVSMLNQYSEAIRGNLTKILRLKIVALVTVEVHARDVISKLAKGGCCDVNAFDWLCQLRLYWEKDVDDCI----IRQTNTHFRYGYEYLGNSGRLVITPLTDRCYMTLTTALHLHRGGSPKGPAGTGKTETVKDLGKSLGMYVIVVNCSEGLDFKSMGRMYSGLAQTGAWGCFDEFNRINIEVLSVVAQQILSILSALSAGLN------NFSFEGRQINLIWSCGIFITMNPGYAGRTELPDNLKSMFRPISMVVPDSTLIAEITLFAEGFNNCKVLAKKVFTLYSLAVQQLSKQDHYDFGLRALTSLLRYAGKKRR-----------ARPDIVDE----------EILLMSMKDMNIAKLSSIDLPLFNGIIQDLFPAVETPTIDYGKLKEAVEAELRQ-SGLQVIPFT----------VTKVIQLYETKNSRHSTMIVGKTGSGKTVTWRTLQNTLSTLHRNGEPGFNLIRECPLNPKAVSLGELYGEYNLSTNEWTDGVLSSLMRM---ACADEKPDEKWIVFDGPVDTLWIESMNSVMDDNKVLTLINGERISMPEQVSLLFEVEDLSVASPATVSRCGMVYSDYSDLGWKPYVQSWMEKRQKVE-----------------------------------TDLLWQLF--ERYIDKTLAFKKTHCKELVAITELNGVASLCRLYQSLATAENGVK--------PADSENYGRMVELWFIFSLIWSVCASVDEEGRKKIDTFLREIE-------GSFPNKDTIYEYYVDTKNKTWASFEDKLPKGWRYASNAPFYKIMVPTVDTVRYHYLVKALVSTQHPVLLTGPVGTGKTSVAQSVLQSLDNITWATLTVNMSSQTSSNNVQEIIESRVEKRIKGVYVPVG--------GKKMVVFLDDLNMPAVDNFGSQPPLELLRLWIDY-GFWYDRQKQTLKYIKDLFLLGSMGPPGG-GRTHISGRLQSRFNLINMTFPTESQIKRIYGTMISQKLQEFEEEVKPIGGILTQATLELYHAITSRFLPTPAKIHYLFNLRDISKVFQGLLRAHKDFHD-TKQSITRLWIHECFRVFSDRLVDHADMETFVGVLSEKLASHFDVPFHTICPN-------KQPPLFGDFLRE---SQIYEDLLDF-KA-LKVHMENQLEDYNLTPGVVPMSLVLFRDAIDHVTRLVRVISQLRGNMLLVGIGGSGRQSLTRLAAYICRFTVFQVEVTKQYRKQEFREDIKKLYRLTGVENKPTVFLFNDTQIVDESFLEDINNILSSGEVPNLYKADELDEIQSALSDSA-RKDNILETPDAMFNYLIERVRNNLHIVLCMSPVGDPFRNRIRQYPALVNCTTIDWFSEWPRDALLEVAERCLDGLSLGSDD------------GI-------QTKVASIFVTVHQSVAQFSHRMKVELKRHNYVTPTNYLELVSGYKKLLSEKRDELGEQVSKLRNGLFKIDDTRTKVEAMSVELEEAKKKVAEFQKQCEEYLVVIVQQKREADEQQKAVGAHSEKIEAEEIKCKAMAENAQRDLDEALPALEEAMKALESLNKKDMTEIKSYGRPPALVETVMQAVMILRGCEPT-WAEAKRQLGEGNFIKQLVNFDKDNISDRVLKTIGQ-YCTQPDFQPEIIGRVSLAAKSLCMWVRAMEVYGRIFRVVEPKRARLHGAMTQLAEKQAALAEAQGKLREVGEKLDHLKRQYDEKLAQKEELRRKSEDMELKLDRAGKLVSGLAGERVRWKETVDGLEKNMSCLVGDCLLAAAFLSYMGPFLSNHRDELVTDIWMKQVRELEVPCSPGFSFAVFLSKPTAVREWNIQGLPSDAFSTENGVIVTRGNRWPLMVDPQGQALKWIKNMEFKQGLKVIDLQMPD--FLRILENAVQFGSPVLLQNVQEELDPSLAPILNKSLTRVGGRFLLKLGDKEIEYSPEFRFYMTTKLSNPHYTPEISSKTTIVNFAVKEQGLEAQLLGIVVRKERPELEEQKDSLVINIASGKRKLQELEDEILRLLNEATGSLLDDVQLVNTLQTSKVTATEVAEQLEISELTESQIDTAREAYRPCAQRASILFFVLNDLGCIDPMYQFSLDAYINLFILSIESSPRSHKLE---ERINNLNRHHTYAVYRYTCRGLFECHKLLFSFHMCAKILEASGKLNM--DEYNFFLRG--GLVLDTKKQMDNPCSHWLSDSNWDNITELDKLTNFHELMASFEQYPRDWHHWYTNPEPEKAPLPGEW--ENSCNE---------LQKMLIVRSLRQDRVSLCVTAFVINNLGSQFVEP--PILDMKAVV-ADSTTRTPLIFVLSPGVDPTAALLQLAETSGMGQRFFALSLGQGQA-PIATRLIKEGVANGHWVFLANCHLSLSWMCELDKLVDELQVQECHPDFRLWLSSSPHPEFPIAILQTGIKITTEPPRGVKWNMKRLYQRVSETQFLRCSRPLLYRKLLFSLCFFHSVILERRKFLQLGWNIIYSFNDSDFEVSENLLSLYLDEY---------EEIPWDALKFLIAGINYGGHVTDDWDRRLLTTYINQYFCPAVIDTPFFKVSSL---VSYYVPRDGSQSSYVDYISQLPALEHPELFGQNPNADIASQITEARTLFHTLLSLQPQVTSTDTTSAGASREDKVLEL--------------SADVLQKIPAEID-YEGTRKLLKDDLSPLNVVLLQEIQRYNTLLHTIRLSLLELEKGIKGLVVMSSSLEETFNCIHDARVPPLWEK-AYPSLKPLASWTRDLCQRVEQFARWAETARP-------PVLFWLSGFTFPTGFLTAVLQSSARQNNVSVDT--LSWEFSVTTVEDNNLLFPPKDGVLIQGLFLEGAGWDKKASCLVEAEPMQL---------VCPMPTIHFKPVESRKRL----AKNMYSCPCYYYPVRSGSSGRQSFVVAVDLKSGAVPYDHWIKRGTAL 4500
BLAST of Cytoplasmic dynein 1 heavy chain 1 vs. Ensembl Zebrafish
Match: dnah2 (dynein, axonemal, heavy chain 2 [Source:ZFIN;Acc:ZDB-GENE-130530-910]) HSP 1 Score: 1424.84 bits (3687), Expect = 0.000e+0 Identity = 1033/3711 (27.84%), Postives = 1844/3711 (49.69%), Query Frame = 3 Query: 3255 YVKTWTNYQSLWDLQGDQLFSLIADDNTVWMNVLEEIKSMRKHFDVAE-TQKEFGPLVIAFGKVQ-SKVSMKYDNWHKEVLTKFGQNMGKMMTT----LYNEVQRARNELEQQSIDSGGTNESVNFITYTQNIKRKMNTWEKQAEACRAGQNILCRDRFQFPNDWLDSENIQGEWSAFKEIMRRKQETISSQVASLQMKITEEDKIVESKTTEVLGNWEKDKPIAGDLTPEEAVNIIQILEGKFNRLKEERENVQKAKEALELTEIGVKPI-SEEKVTNALSELHDLKNVWNELKSIWEKIRDMKETPWLSVQPRKLRQDIENLTAQLKELPNSFK--QYASFEHVRTLLKMYMKVNASIVELKSEAIKERHWRMLMRKLNVSW--SLNELQLGKVWDIDLVKNEEIIREVLAIAQGEKALEEYLRQITEVWKNYVLELTNYQSKSK-IIKGWDDLFNKVKEHINNVTSMKASPYFKQFEEEATAWEDRLNKINALFDVWIDVQRRWIYLDGIFAGSADIKVLLPVESQRFQSVSTEFLGLMKKVQKSPLVTDVLNIANVQRQLERLADL---LGKIQKSLGEYLERQRSSFPRFYFVGDEDLLEIIGNSXXXXXXXXXXXXMFAGVHSIILSE----DEKVILGMMSKEGEELRFISPVSIIEHPRINDWLTAMEKEMRVSLAKYL---NVAVKEISGWRTESNIDKDKFMVWLDKYQAQIVVLAAQITWSEAVEASL------ASGVSLESTMTVVHSTLNMLADTVLYEQPPVRRRKLEHLIIEYVHQRDVLRALHNDGVSSNKNFDWMSQMRFYFDPKQTDPLHQLSIHVANAKFHYGFEYLGVCDRLVQTPLTDRCYLTMTQALEARLGGSPFGPAGTGKTESVKSLGNQLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLSAVSQQIQGIQEALRELMVSKKDSINVELLGKQVHVNPDMAIFITMNPGYAGRSNLPDNLKKLFRSLAMTQPDRQLIAQVMLYSQGFRTAEVLAGKVVPFFKLCDEQLSPQSHYDFGLRALKSVLVSAGNVKRDRIKQEKEKIVARGEEINETAIAEQLPEQEILIQSVMETMVPKLIADDIPLLYSLLTDVFPGVEYRQAEMKRLRE----ELRKVSENKFLVYSDEPNTAGYLWVEKVLQLYQITTIHHGLMMVGPSGSGKTMACRVLLQALENI--DGIEGVAHI----IDPKSISKDSLYGYMDPNTREWTDGLFTHILRRIIDSVRGESNKRQWIVFDGDVDPEWVENLNSVLDDNKLLTLPNGERLAIPPNVRIMFEVQDLKYATLATVSRCGMVWFSEEVLTTGMILTHFLNELKKVQVMEGEEDFSVNQGDTGADADSKISSSPIIQLQTQVSSILAPFFTEDGLIAKCLDYSTT-LEHIMDFTRLRALTSLFSMIKQ--SIRNMIEYNQSHSDFPLNNEQIENYVAKSLISSVVWSMSGDSKLKVREQLSQYIKNISTVDLPTVGGIKN---IIDFEVNIQG-TWVAWSNKVPQIEVETHKITATDVVVPTMDTVRHEALLYTWLAEHRPVLLCGPPGSGKTMTLFSALRCLPDM--EVVGLNFSSATTPELMLKTFDQYCEYR----KTPNGIVLAPQQLNKWLIFFCDEINLPDMDKYGTQRVISFLRQMVEHHGFYRITDMQWVSFERIQFV-GACNPPTDPGRKPLSHRFLRHVPVVYVDYPGETSLKQIYSTF-NRAMLRMLPSLRGYADTLTNAMVEFFLKTQERF-THDMQPHYIYSPREMTRWVRGIHEALKPLESLSVEGLVRIWAHEALRLFQDRLVEEDERHWTDDNINEVALKHF--------PNINKEEALKRPILYSNWLSKDYSAVTQEELRDYVKARLKVFYEEELD--------VP--LVLFNQVLDHVLRIDRVFRQPQGHLLLIGVSGAGKTTLSRFVSWINGLSVFQVKVHNKYTAEDFDEDLRNVLRRSGCKGEKITFIMDESNVMDSSFLERMNTLLANGEVPGLFEGDELTTLMTQCKEGAIREGLMIDSQEELYKWFTQQICRNLHVVFTMNPSADGLKDKASTSPALFNRCVLNWFGDWSLEAYFQVGKEFTNRLDLERTDYKVPDTLPCIAEGLLPQNPIYRDVVVNALVFVHQTMHQANVRVQKRGGRTAAITPRHYLDLIAHYMKLSAEKRADLEEQQLHLNNGLKKIEQTVDQVEVMQRSLTKKRQELENMNEAANAKLKQMVQDQQEAEQKKTTGQALKEELAKQEQFVNEKQKTVKQELDQVEPTVNEAKQAVQNIRKKDIQEIKAMKNPPNAVKMAVESICLLLGEKTTDWQSILKVIIKDTFVTSILNFNTDDVSDNTRETMKKKYLSNPDYNFEKVNKASNACGPMVKWVLAQISYADILKRVEPLRNELTELSDAAEQNRKKSQETEDLIAQLEKSIAKYTEEYATLISQAQTIKSDLASVESKVGRSVALLGSLSSERTRWDSGSETFKAQMATINGDCLLSSAFMAYGGYFDQHMRTSLF-NTWCHHLSEADILFRSDLARVEYLSNPDDRLRWQANSLPADDLCVENAIILRRYNRYPLIIDPSGQATTFLLN-EYKEK-KITKTSFLDDSFRKTLESALRFGTPLLVQDV-ESYDPILNPVLNREVRRTGGRTLITLGDQDIDLSPTFTIFLSTRDPSVEFAPDICSRVTFVNFTVTRSSLQNQCLNAVLKIERPDIDQKRSDLLKAQGEFQLKLRHLEKDLLQSLNEAQGNLLENDKIIARLETLKREAADVAKKVEETDVVMQEVESVSTEYVPLAQSCSNIYFTLEAMNQIHFLYQYSLQLMLDIFSSVLINNPELTNVKAASDRLKIITKNLFQVTYNRLARGMLHEDQITFATILARIFLKGSTPIGFLENEFQHFLRSQEATITSSDSNKQDNLGLTLHQDQIDSVKRLKKLKVFAKIEEKVKS-TKDIKNWTLTVTPE-SNVPELWVDDNNYNDEKLSKIAKGMYNLLIIQAIRPDRLLASTQKFIASVLGDTFTESVRGTLDLASIVEVEVTACVPILLCAVQGYDPSGRVEDLA--SEQGKQLTGIAIGSAEGFSQAEKAINSAAKTGKWVMLKNVHLATSWLVSLEKKIHSLQ---AHPNFRLFLTMEITPKLPVNLLRAGRVLVFEPPPGIKANLLRTLSSINNQRM--SKEPVERSRLYFLLAWLNAIVQERLRYVPLGYSKKYEFGESDFKCALDTIDTWVDGAAMGRTNLPPEKIPWVALQTLLGSCIYGGKIDNAFDQRLLNSFLGYLFTEKCFDHNFALVSDADDGSNIAFPESTKHTDILQWVHKLPDLQTPSWLGLPNSAEKVLLTNLGQSLIGNILKMQQSLEDDEELVVGQSKTKRTIEVGDGRPAWMRQLYQSTQTWLQILPKSVTPLQRTIENIKD---PMYRCFEREVNSGCNLLASVRKDLEDVAEVCKGAKKPTNHHRSMMADLAKGIIPKMWIRYAIPPGLTVIQWIQDFADRIKQLLHISDTAAKSGVIALRSIQVWLGGLFMAEAYITATRQSVAQNNKWALEELFLDVELGEGKVDSNT--------CVITGLRLMG-------SEIVDPRTLKLSTLIYKDIDICRLKWIR---VEKSQQLEGSSAKDKVCLPIYL------NAARSTVLFTLYFSTTDSSYDFY-KRGVAI 14048 Y+KTW ++ +W+++ D N + +I ++ +VA QKE L + F + S + E +KF Q + M ++ L++ +Q L Q ES+ + + ++ +N E Q IL + E + EW F++++ + +++ + + + KT L ++ + P +TP A+ + L + LKEE +N+ + + K I + EK + L ++ ++ W +L + W K S+Q + + + L +L +FK + + ++ ++ + K+ I +L++ A++ERHW + +++ ++ S + L K+ + L + E I ++ A E ++E+ L I + WK L++T ++ K ++G D++F ++++ ++ +KAS + K FE+E WE L+ + + ++ + VQR+W+YL+ IF DI+ L E+ F +V++ + +M+++ K + L + LE+L+++ L +IQKSL YLE +R FPRFYF+ ++DLLEI+G S++ + +Q H KK F + S+ +++ ++ GM S +GE + F PV ++E P + WL +E+ MR +L L ++A+K++ G R + W+ + Q+++ A+QI W+ V +L A +L+S S LN ++ + + R K+ L+ VH RDV+ L G FDW+ Q+R Y++ D + I N F YG+EYLG RLV TPLTDRCY+T+T AL GGSP GPAGTGKTE+VK LG LG +V+V NC E DF++MGR++ GL Q GAWGCFDEFNR+ +LS V+QQI I AL + N G+Q+++ IFITMNPGYAGR+ LPDNLK +FR ++M PD LIA++ L+++GF +VLA KV + L +QLS Q HYDFGLRAL S+L AG +R AR + ++E EIL+ S+ + + KL + D+PL ++ D+FP VE + +L+E ELR+ S + + ++ V KV+QLY+ H M+VG +GSGKT+ R L L + +G G I ++PK++S LYG + +T EWTDG+ + ++R + E +WIVFDG VD W+E++NSV+DDNK+LTL NGER+++P V ++FEV+DL A+ ATVSRCGMV+ L + ++ + +KV+ + +L F + I K L + T + ++ T L + SL + + + N ++ P ++E V I S++WS+ + R+++ +++ I G N I ++ V+ + TW ++ +K+P+ ++VPT+DTVR+ L+ ++ PVLL GP G+GKT S L+ L ++ + +N SS T+ + + + E R P G K ++ F D++N+P +D +G+Q + LR +++ GF+ Q + + + F+ G+ PP GR +S R ++ + +P E+ +K+IY T ++ + ++ LT A +E + RF + HY+++ R++++ +G+ A K + + + R+W HE R+F DRLV+ + ++E HF PN K+P L+ ++L + + E+L D+ KA LKV E +L+ VP LVLF +DHV R+ RV Q +G++LL+G+ G+G+ +L+R ++I +VFQV+V +Y ++F ED++ + R +G + + F+ +++ ++D SFLE +N +L++GEVP L++ DEL + + + A R+ ++++ + ++ + +++ NLH+V M+P D +++ PAL N ++WF +W +A +V + + L L D G+ + V + V VHQ++ Q + R++ R +TP +YL+L++ Y KL +EKR +L EQ L NGL KI+ T +VE M L + ++++ + L +VQ ++EA++++ A E++ +E + +++LD+ P + EA +A++++ KKD+ EIK+ PP V+ ++++ +L G + T W + + + F+ ++NF+ D++SD +T+ + Y + PD+ E + + S A + WV A Y I + VEP R L + + E + + ++ + + +Y ++Q + ++ +E K+ R+ L+ L+ ER RW + + M+ + GDCLL++AF++Y G F + R L + W + E ++ + +LS P W LP+D EN +I+ R NR+PL++DP GQA ++ N E+K+ K+ D F + LE+A++FG+P+L+Q+V E DP L P+LN+ + R GGR L+ LGD++I+ SP F +++T+ + + P+I S+ T VNF V L+ Q L V++ ERP++++++ L+ + KL+ LE ++L+ LNEA G+LL++ +++ L+T K A +VA+++E +++ ++++ Y P AQ S ++F L + I +YQ+SL +++F + ++P ++ +R+ + ++ Y RG+ ++ F+ + L+ S + +E+ FLR + + + L D++ L KL F ++ + +D +W PE + +P W +N+ N+ + +LI++++R DR+ F+ + LG F E LD+ ++V + T P++ G DP+ + LA S G++ +++G + A + I G WV L N HL+ SW+ L+K + LQ HP+FRL+L+ P+ P+ +L+ G + EPP G+K N+ R ++ + P+ +L F L + ++++ ER +++ LG++ Y F +SDF+ + + + ++D E+IPW AL+ L+ YGG + + +D+RLL +++ F D F VS + P + + ++ +LP L+ P G +A+ ++L +L +Q + + G S+ + +E+ + LQ +P + + T + +KD P+ +E+ LL ++R L ++ + KG ++ + +P +W + A P + W +D R++Q ++TA + WL G ++TA QS A+ N +++ L E V+ N +I GL L G S +V+ ++L +C + I VE ++L AK+ P Y ++ R + + + + YD + KRG A+ Sbjct: 914 YLKTWDKHREIWEIEKDSFIQRYQRLNPTVTSFDADIA---RYTEVANNVQKEETLLSVQFVLLDCSPLKFSLLQHCNEWQSKFTQLLSLMASSKLKELHSFLQENAVRLSQPPQTLTDLGESLKLL---ETLQADLNKIESQIPPIHEQYAILTKYEVAVDPVLELLEALNAEWVWFQQVVIDSDIMLKKHKDTMKSGLILSSEEFQKKTQTFLQSFSSNGPFGSSVTPHSALQQVSELRAQLEALKEEEQNICSGLNIFTIEQPASKDILALEKDVDYLQQVWEIARQWEDLWAEW------KGGHLASLQTEVMDNTAQTMFKTLHKLSRAFKDKHWEIVDSSKSRIEQFKKIIPLITDLRNSALRERHWNQIRQEVQQTFDPSSADFTLEKIVALGLDHHAESISDISGAASKELSIEQTLEGIMKTWKEMSLDITPHKDKGHHKLRGTDEVFQALEDNQVTLSVIKASRFVKAFEKEVDHWERCLSLVLEVIEMILTVQRQWMYLENIFLAD-DIRKQLVRETAEFDAVTSSWKIIMERLDKD---KNALRGTHHPGLLEKLSEMNTKLEEIQKSLDMYLETKRQIFPRFYFLSNDDLLEILGQSRNPEAVQPHLKKCFDNIKSLRINKVGTGNKSEASGMFSADGEFVDFTHPV-LLEGP-VEAWLCDVERTMRWTLKDSLRNCSMALKKMPGKRGK----------WVRDWPGQMLITASQIQWTTDVTRALMTSKERADKSALKSLKKKQVSMLNQYSEAIRGNLTKILRLKIVALVTVEVHARDVISKLAKGGCCDVNAFDWLCQLRLYWEKDVDDCI----IRQTNTHFRYGYEYLGNSGRLVITPLTDRCYMTLTTALHLHRGGSPKGPAGTGKTETVKDLGKSLGMYVIVVNCSEGLDFKSMGRMYSGLAQTGAWGCFDEFNRINIEVLSVVAQQILSILSALSAGLN------NFSFEGRQINLIWSCGIFITMNPGYAGRTELPDNLKSMFRPISMVVPDSTLIAEITLFAEGFNNCKVLAKKVFTLYSLAVQQLSKQDHYDFGLRALTSLLRYAGKKRR-----------ARPDIVDE----------EILLMSMKDMNIAKLSSIDLPLFNGIIQDLFPAVETPTIDYGKLKEAVEAELRQ-SGLQVIPFT----------VTKVIQLYETKNSRHSTMIVGKTGSGKTVTWRTLQNTLSTLHRNGEPGFNLIRECPLNPKAVSLGELYGEYNLSTNEWTDGVLSSLMRM---ACADEKPDEKWIVFDGPVDTLWIESMNSVMDDNKVLTLINGERISMPEQVSLLFEVEDLSVASPATVSRCGMVYSDYSDLGWKPYVQSWMEKRQKVE-----------------------------------TDLLWQLF--ERYIDKTLAFKKTHCKELVAITELNGVASLCRLYQSLATAENGVK--------PADSENYGRMVELWFIFSLIWSVCASVDEEGRKKIDTFLREIE-------GSFPNKDTIYEYYVDTKNKTWASFEDKLPKGWRYASNAPFYKIMVPTVDTVRYHYLVKALVSTQHPVLLTGPVGTGKTSVAQSVLQSLDNITWATLTVNMSSQTSSNNVQEIIESRVEKRIKGVYVPVG--------GKKMVVFLDDLNMPAVDNFGSQPPLELLRLWIDY-GFWYDRQKQTLKYIKDLFLLGSMGPPGG-GRTHISGRLQSRFNLINMTFPTESQIKRIYGTMISQKLQEFEEEVKPIGGILTQATLELYHAITSRFLPTPAKIHYLFNLRDISKVFQGLLRAHKDFHD-TKQSITRLWIHECFRVFSDRLVDHADMETFVGVLSEKLASHFDVPFHTICPN-------KQPPLFGDFLRE---SQIYEDLLDF-KA-LKVHMENQLEDYNLTPGVVPMSLVLFRDAIDHVTRLVRVISQLRGNMLLVGIGGSGRQSLTRLAAYICRFTVFQVEVTKQYRKQEFREDIKKLYRLTGVENKPTVFLFNDTQIVDESFLEDINNILSSGEVPNLYKADELDEIQSALSDSA-RKDNILETPDAMFNYLIERVRNNLHIVLCMSPVGDPFRNRIRQYPALVNCTTIDWFSEWPRDALLEVAERCLDGLSLGSDD------------GI-------QTKVASIFVTVHQSVAQFSHRMKVELKRHNYVTPTNYLELVSGYKKLLSEKRDELGEQVSKLRNGLFKIDDTRTKVEAMSVELEEAKKKVAEFQKQCEEYLVVIVQQKREADEQQKAVGAHSEKIEAEEIKCKAMAENAQRDLDEALPALEEAMKALESLNKKDMTEIKSYGRPPALVETVMQAVMILRGCEPT-WAEAKRQLGEGNFIKQLVNFDKDNISDRVLKTIGQ-YCTQPDFQPEIIGRVSLAAKSLCMWVRAMEVYGRIFRVVEPKRARLHGAMTQLAEKQAALAEAQGKLREVGEKLDHLKRQYDEKLAQKEELRRKSEDMELKLDRAGKLVSGLAGERVRWKETVDGLEKNMSCLVGDCLLAAAFLSYMGPFLSNHRDELVTDIWMKQVRELEVPCSPGFSFAVFLSKPTAVREWNIQGLPSDAFSTENGVIVTRGNRWPLMVDPQGQALKWIKNMEFKQGLKVIDLQMPD--FLRILENAVQFGSPVLLQNVQEELDPSLAPILNKSLTRVGGRFLLKLGDKEIEYSPEFRFYMTTKLSNPHYTPEISSKTTIVNFAVKEQGLEAQLLGIVVRKERPELEEQKDSLVINIASGKRKLQELEDEILRLLNEATGSLLDDVQLVNTLQTSKVTATEVAEQLEISELTESQIDTAREAYRPCAQRASILFFVLNDLGCIDPMYQFSLDAYINLFILSIESSPRSHKLE---ERINNLNRHHTYAVYRYTCRGLFECHKLLFSFHMCAKILEASGKLNM--DEYNFFLRG--GLVLDTKKQMDNPCSHWLSDSNWDNITELDKLTNFHELMASFEQYPRDWHHWYTNPEPEKAPLPGEW--ENSCNE---------LQKMLIVRSLRQDRVSLCVTAFVINNLGSQFVEP--PILDMKAVV-ADSTTRTPLIFVLSPGVDPTAALLQLAETSGMGQRFFALSLGQGQA-PIATRLIKEGVANGHWVFLANCHLSLSWMCELDKLVDELQVQECHPDFRLWLSSSPHPEFPIAILQTGIKITTEPPRGVKWNMKRLYQRVSETQFLRCSRPLLYRKLLFSLCFFHSVILERRKFLQLGWNIIYSFNDSDFEVSENLLSLYLDEY---------EEIPWDALKFLIAGINYGGHVTDDWDRRLLTTYINQYFCPAVIDTPFFKVSSL---VSYYVPRDGSQSSYVDYISQLPALEHPELFGQNPNADIASQITEARTLFHTLLSLQPQVTSTDTTSAGASREDKVLEL--------------SADVLQKIPAEID-YEGTRKLLKDDLSPLNVVLLQEIQRYNTLLHTIRLSLLELEKGIKGLVVMSSSLEETFNCIHDARVPPLWEK-AYPSLKPLASWTRDLCQRVEQFARWAETARP-------PVLFWLSGFTFPTGFLTAVLQSSARQNNVSVDT--LSWEFSVTTVEDNNLLFPPKDGVLIQGLFLEGAGWDKKASCLVEAEPMQL---------VCPMPTIHFKPVESRKRL----AKNMYSCPCYYYPVRSGSSGRQSFVVAVDLKSGAVPYDHWIKRGTAL 4380
BLAST of Cytoplasmic dynein 1 heavy chain 1 vs. Ensembl Zebrafish
Match: AL807739.1 (dynein, axonemal, heavy chain 6 [Source:NCBI gene;Acc:100148193]) HSP 1 Score: 1378.62 bits (3567), Expect = 0.000e+0 Identity = 943/3324 (28.37%), Postives = 1673/3324 (50.33%), Query Frame = 3 Query: 4101 VWNELKSIWEKIRDMKETPWLS-----VQPRKLRQDIENLTAQLKEL-----PNSFKQY--ASFEHVRTLLKMYMKVNASIVELKSEAIKERHWRMLMRKLNVSWSLNELQ-LGKVWDIDLVKNEEIIREVLAIAQGEKALEEYLRQITEVWKNYVLELTNYQSKSK--IIKGWDDLFNKVKEHINNVTSMKASPYFKQFEEEATAWEDRLNKINALFDVWIDVQRRWIYLDGIFAGSADIKVLLPVESQRFQSVSTEFLGLMKKVQKSPLVTDVLNIANVQRQLERLADLLGKIQKSLGEYLERQRSSFPRFYFVGDEDLLEIIGNSXXXXXXXXXXXXMFAGVHSIILSE--------DEKV--------ILGMMSKEGEELRFISPVSIIEHPRINDWLTAMEKEMRVSLAKYLNVAVKEISGWRTESNIDKDKFMVWL-DKYQAQIVVLAAQITWSEAVEASLASG----VSLESTMTVVHSTLNMLADTVLYEQPPVRRRKLEHLIIEYVHQRDVLRALHNDGVSSNKNFDWMSQMRFYFDPKQTDPLHQLSIHVANAKFHYGFEYLGVCDRLVQTPLTDRCYLTMTQALEARLGGSPFGPAGTGKTESVKSLGNQLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLSAVSQQIQGIQEALRELMVSKKDSINVELLGKQVHVNPDMAIFITMNPGYAGRSNLPDNLKKLFRSLAMTQPDRQLIAQVMLYSQGFRTAEVLAGKVVPFFKLCDEQLSPQSHYDFGLRALKSVLVSAGNVKRDRIKQEKEKIVARGEEINETAIAEQLPEQEILIQSVMETMVPKLIADDIPLLYSLLTDVFPGVEYRQAEMKRLREELRKVSENKFLVYSDEPNTAGYLWVEKVLQLYQITTIHHGLMMVGPSGSGKTMACRVLLQALENIDGIEGVAH-----------IIDPKSISKDSLYGYMDPNTREWTDGLFTHILRRIIDSVRGESNKRQWIVFDGDVDPEWVENLNSVLDDNKLLTLPNGERLAIPPNVRIMFEVQDLKYATLATVSRCGMVWFSEEVLTTGMILTHFLNELKKVQVMEGEEDFSVNQGDTGADADSKISSSPIIQLQTQVSSILAPFFTEDGLIAKCLDYSTTLEHIMDFTRLRALTSLFSMIKQSIRNMIEYNQSHSDFPLNNEQIENYVAKSLISSVVWSMSGDSKLKVREQLSQYIK----NISTVDLPTVGGIKNI-IDFEVNIQGTWVAWSNKVPQIEVETHKITATDVVVPTMDTVRHEALLYTWLAEHRPVLLCGPPGSGKTM---TLFSALRCLPDMEVVGLNFSSATTPELMLKTFDQYCEYRKTPNGIVLAPQQLNKWLIFFCDEINLPDMDKYGTQRVISFLRQMVEHHGFYRITDMQWVSFERIQFVGACNPPTDPGRKPLSHRFLRHVPVVYVDYPGETSLKQIYSTFNRAMLRMLPS-LRGYADTLTNAMVEFFLKTQERFTHDMQP-----HYIYSPREMTRWVRGIHEALKPLESLSVEGLVRIWAHEALRLFQDRLVEEDERHWTDDNINEVALKHFPNINKEEA--LKRPILYSNWLS-------KDYSAVT-----QEELRDYVKARLKVFYEEELDVPLVLFNQVLDHVLRIDRVFRQPQGHLLLIGVSGAGKTTLSRFVSWINGLSVFQVKVHNKYTAEDFDEDLRNVLRRSGCKGEKITFIMDESNVMDSSFLERMNTLLANGEVPGLFEGDELTTLMTQCKEGAIREGLMIDSQEELYKWFTQQICRNLHVVFTMNPSADGLKDKASTSPALFNRCVLNWFGDWSLEAYFQVGKEFTNRLDLERTDYKVPDTLPCIAEGLLPQNPIYRDVVVNALVFVHQTMHQANVRVQKRGGRTAAITPRHYLDLIAHYMKLSAEKRADLEEQQLHLNNGLKKIEQTVDQVEVMQRSLTKKRQELENMNEAANAKLKQMVQDQQEAEQKKTT---GQALKEELAKQEQFVNEKQKTVKQELDQVEPTVNEAKQAVQNIRKKDIQEIKAMKNPPNAVKMAVESICLLLGEKTTDWQSILKVIIKDTFVTSILNFNTDDVSDNTRETMKKKYLSNPDYNFEKVNKASNACGPMVKWVLAQISYADILKRVEPLRNELTELSDAAEQNRKKSQETEDLIAQLEKSIAKYTEEYATLISQAQTIKSDLASVESKVGRSVALLGSLSSERTRWDSGSETFKAQMATINGDCLLSSAFMAYGGYFDQHMRTSLFNTWCHHLSEADILFRSDLARVEYLSNPDDRLRWQANSLPADDLCVENAIILRRYNRYPLIIDPSGQATTFLLNEYKEKKITKTSFLDDSFRKTLESALRFGTPLLVQDV-ESYDPILNPVLNREVRRTGGRTLITLGDQDIDLSPTFTIFLSTRDPSVEFAPDICSRVTFVNFTVTRSSLQNQCLNAVLKIERPDIDQKRSDLLKAQGEFQLKLRHLEKDLLQSLNEAQGNLLENDKIIARLETLKREAADVAKKVEETDVVMQEVESVSTEYVPLAQSCSNIYFTLEAMNQIHFLYQYSLQLMLDIFSSVLINNPELTNVKAASDRLKIITKNLFQVTYNRLARGMLHEDQITFATILARIFLKGSTPIGFLENEFQHFLRSQEATITSSDSNKQDNLGLTLHQDQIDSVKRLK-KLKVFAKIEEKVKSTK---DIKNWTLTVTPE---SNVPELWVDDNNYNDEKLSKIAKGMYN--------LLIIQAIRPDRLLASTQKFIASVLGDTFTESVRGTLDLASIVEVEVTACVPILLCAVQGYDPSGRVEDLASEQGKQ--LTGIAIGSAEGFSQAEKAINSAAKTGKWVMLKNVHLATSWLVSLEKKIHSLQA-----HPNFRLFLTMEITPKLPVNLLRAGRVLVFEPPPGIKANLLRTLSSINNQRMSKEPVERS--RLYFLLAWLNAIVQERLRYVPLGYSKKYEFGESDFKCALDTIDTWVDGAAMGRTNLPPEKIPWVALQTLLGSCIYGGKIDNAFDQRLLNSFLGYLFTEKCFDHNFALVSDADDGSNIAF-PESTKHTDILQWVHKLPDLQTPSWLGLPNSAEKVLLTNLGQSLIGNILKMQQSLEDDEELVVGQSKTKRTIEVGDGRPAWMRQLYQSTQTWLQILPKSVTPLQRTIEN--IKDPMYR------CFEREVNSGCNLLASVRKDLEDVAEVCKGAKKPTNHHRSMMADLAKGIIPKMWIRYAIPPGLTVIQWIQDFADRIKQLLHISDTAAKSGVIALRSIQVWLGGLFMAEAYITATRQSVAQNNKWALEEL 13736 +W+ L+ WE + E WL + P L + + + +L PN+ + A E +R L + I +L++ +K RHW ML ++ S L E Q L + +ID+ + I+EV A GE +LE LR+I + WK + ++ I+ G DD+ + + I NV ++ +S Y + W+ +L N D W+ QR W+YL+ IF+ + DI+ LP E++ F V + +M+KV + P + + LL +IQK L YLE +R FPRFYF+ +++LLEI+ +++ + +Q H +K F + + + D+ V IL M+S EGE++ + + + DWL +E+ M SL + A I+ ++++ ++ W+ + +Q+V+ +Q+ W ++ L +L+ LN LA V P + R + LI VH RD++ L + V S+ NF+W Q+R+Y+D D + ++++ +++ YG+EYLG C RLV TPLTDRCYL + AL+ LGG+P GPAGTGKTE+ K L L +VFNC + D++ MG F GL Q GAW CFDEFNR+ +LS ++QQ+ I+ A +K E G+++ + A FITMNPGYAGR+ LPDNLK LFR +AM P+ LIA+V+LYS+GF +++ LA K+ +KLC EQLS Q HYDFG+RA+KSVLV AG++KR+ L E +LI+++ ++ +PK + DD L +L+D+FPGV + + L+ + + S +P + + KV+QLY+ + HG+M+VGP+GSGKT RVL L D + H +++PKS+S LYG ++P T EW DGL +R +V+ S+ +W++ DG VD W+EN+N+VLDDNK+L L N ER+ + P++ +MFEVQDL A+ ATVSRCGMV+ E L + +L + ++ + + + + + + +S +Q QV I+K LE + LFS S++ + + ++ N + ++ + +W++ G+ + +++ + + LP+VG + ++ ++F++ W ++ + +I +++VPT DTVR+ L+ L+ + VL G G GK++ L ++++ V +NFS+ T+ + + E ++ I+ AP NK ++ F D++N+P +D YG+Q I LRQ + HGFY W + AC PP GR P++ RF+RH ++ + P E+SLKQI+ L + ++ AD++ +A VE + R + D+ P HY+++ R++++ V+G+ + +P + R++ HE R+F DRL+ +++ + + I+E+A K+F +IN E A + +PI++ +++ + Y +T ++ L+DY+ F +E LV F ++HV RI R+ RQ +G+ LL+GV G GK +L+R + + G FQ+++ Y + F EDLR + R +G +G+ + F+ ++ ++ FLE +N +L +GEVP LFE DEL ++ A G+ +++E++++F ++ LH+V M+P D + + P+L N C ++WF W EA V + F ++ + K C +E V +H ++ R R TP YL+LI Y+ + EKR L+ + + NGL K+ +T + V+ M++ L+ L + +A ++++ DQ+ A+Q + +AL + A++ Q + + +++LD+ P ++ A +A+ + K DI E++ PP+ V +E++C+LL KT DW S +++ F+ +++++ D++ + + K Y+SNPD+ EKV K S AC M WV A Y+ +LK V P R +L + +E ++ + ++E I E++ + +++ +T+ +A E+++GRS L +L E+ RW F+ ++ + G+ +++A +AY G F H R L + W I + + + L +P + +W A LP D++ EN I++ R R+PL+IDP QA ++ ++ + + D F +TLE+A+R G P+L++++ E+ DP L P+L ++ +GGRTLI LGD DID F +++T+ + + P++C +VT +NFTVT+S L++Q L+ V+++ERPD++++RS L+ + +L+ +E +L+ L ++GN+L+N++++ L+ K + + ++ E + + + +Y P+A S +YF + ++++I +YQ+SL+ +F++ I + E K S RL+I+ Y ++RG+ + + ++ +L + I + E+ +FLR I K + L+ ++ L+ +L F I++++ ST + +TV+PE V +L EK ++ +G +N L++I++ ++++++ +F+ + LG F E+ +DL ++ +++ +P++ G DP G + A+E+G Q + I++G +G AE+ I A K G W+ L+N HLA SW++++E+ I S H +FRLFL+ T PV +L+ + EPP G++AN+ R + I++ + + R ++ F + + +AI+QER ++ PLG++ +YEF +SD +CAL ++ + IPW AL + G YGG++ +A+DQR L + L F+ + + S I F P+S T+ Q++ LP + P G+ +A ++I IL++Q R+ G G+ + +++ + L +P + + +E+ ++DP R +EV+ LL ++ L + + G + + +P W A P + W++D L++ +S + + W+ G F + ++T Q+ A+ ++EL Sbjct: 901 LWDSLEE-WESL----ENGWLQDKFDELDPELLSKQVNRFVKYVSQLEKGLPPNNVVPFLKAKVESMREKLPV-------ITDLRNPCLKARHWEMLEAIVD-SKLLEEAQTLATLQNIDIFRFGLQIQEVSGQASGEASLENILRKIEDSWKTTEFIVLPHRDTKDVFILGGTDDIQVLLDDSIVNVATVASSRYAGPIKARVDKWQRQLLLFNQTLDEWLLCQRSWLYLESIFS-APDIQRQLPAEAKMFLQVDKSWKEIMRKVNRMPNALRAATQTGILDVFQNNNALLERIQKCLEAYLESKRVIFPRFYFLSNDELLEILAQTRNPQAVQPHLRKCFDAISQLEFATLTPTTPEGDDTVEKIQYTNDILSMVSPEGEKV--VLGKGLKARGNVEDWLGKVEEAMFSSLRRLSKAA---IADYQSKPRVE------WVVAGHPSQVVLTISQLMWCRDMDNCLEGEHDHFQALQEFEITNFERLNALAALVRGNLPSLHRNIITALITIDVHARDIVTDLVKEQVDSSDNFEWQRQLRYYWDVDLDDCVARMAL----SQYIYGYEYLGACPRLVITPLTDRCYLCLMGALQLDLGGAPAGPAGTGKTETTKDLAKALAIQCVVFNCSDGLDYKMMGTFFSGLAQSGAWCCFDEFNRINIEVLSVIAQQLITIRNA----KAAKLSRFMFE--GREIKLVMTCAAFITMNPGYAGRTELPDNLKALFRPIAMMVPNYALIAEVILYSEGFESSKTLARKMTQMYKLCSEQLSQQDHYDFGMRAVKSVLVMAGSLKREN---------------------PNLSEDVVLIRALRDSNLPKFLKDDAALFSGILSDLFPGVTIPEHDYGVLQSTIH----SSLCQRSLQPLPS---IISKVIQLYETMLVRHGVMLVGPTGSGKTTVYRVLADTL---DTLHHAGHPNPFFRPVKTYVLNPKSVSMGELYGEVNPLTLEWRDGLMALCVRA---AVQDFSDDHKWVISDGPVDALWIENMNTVLDDNKMLCLANSERIKLTPSIYMMFEVQDLAVASPATVSRCGMVYIDPEELKWMPYVQTWLTGFAE-KISDPVRGYLMELFEQYVEKGLQFASKHCLQAVAQVD------------ISKVTTLCCLLEAL-----------LFSDGAPSLK-------------MESSKLNNVLCQTFVFCYLWAVGGNLIESHWDTFDTFVRQQFEDNTDAKLPSVGDLWSVYMNFDIKCLEPW----ERIIPVFSYNSEIPFFEMLVPTTDTVRYGYLMEKLLSVNHSVLFTGITGVGKSVVARALLNSVQEKAGYVPVYINFSAQTSSARTQEIIESKLEKKR--KNILGAPA--NKKIVVFVDDLNMPKLDSYGSQPPIELLRQFQDFHGFYDREKFFWKEIHDMTIAAACAPPGG-GRNPVTPRFIRHFSMLCLPTPSESSLKQIFKAILGGFLTEFSTAVKQAADSIVDAAVEIY----HRMSVDLLPTPAKSHYVFNLRDLSKCVQGMLQC-EPTTVRDQTHIFRLFCHECQRVFHDRLINNEDKSYFNTMISEMASKYF-SINIEPAYFVNQPIIFGDFIKVGADKADRVYEDLTDMDKIRQVLQDYLDDYNTTFAKE---TKLVFFQDAIEHVSRIARMIRQERGNALLVGVGGTGKQSLTRLAAHMCGYRCFQIELSRGYNYDSFHEDLRKLYRMAGVEGQDMVFLFTDTQIVVEEFLEDINNMLNSGEVPNLFEKDELKQVLAAISPKAKEAGISEGNRDEVFQFFISRVREKLHIVLCMSPVGDSFRSRCRMFPSLVNCCTIDWFVQWPREALLSVSQTFFQNVEFGSEEMK-----QCFSE---------------MCVEIHVSVTDMAERFYSELRRHYYTTPTSYLELINLYLGMLGEKRQQLQAARDRIKNGLTKLLETNELVDKMKQDLSALEPVLAQKSIDVSALMEKLAVDQENADQVRRVVKEDEALAKVKAEETQAIADD---AQRDLDEALPALDSANKALNALDKADISEMRVFTKPPDLVMTVMEAVCILLSNKT-DWASAKQLLGDGNFLKKLMDYDKDNIKPQILQKLHK-YISNPDFVPEKVEKVSKACKSMCMWVRAMDLYSRVLKEVGPKREKLAAAQVELDATMSTLKEKQNKLQEVENQIKVLQEQFESSMAEKETLAKTMALTEARLGRSGKLTSALGDEQVRWQESITLFEQEIHNVIGNVFIAAACVAYYGAFTSHYRQLLIDHWITRCQSLGIPISDNFSLIGILGDPYEIRQWNAEGLPRDNVSTENGILVMRGRRWPLMIDPQDQANRWIRSKETKNGLKVIKLTDAGFLRTLENAIRLGMPVLLEELKETLDPALEPILLKQTFVSGGRTLIRLGDSDIDYDKNFRFYMTTKMANPHYLPEVCIKVTIINFTVTKSGLEDQILSDVVRLERPDLEEQRSQLIVRINADRNQLKAIEDRILKLLFTSEGNILDNEELVQTLQESKVTSQAIKSRLVEAETTEEMINRAREKYRPVATRGSIMYFVIASLSEIDPMYQFSLKYFKQLFNNT-IESAE--KHKDLSLRLQILLDQTLLSAYTNVSRGLFEQHKAIYSFMLCVEIMMQRGEIS--QQEWLYFLRGA-GGIRKELPEKPEVPWLS--DFAWETCCNLEDRLPCFNGIKKEIISTPISVKLGQLEVTVSPEHWDGYVTDLPPFSEEIPSEKQPQV-RGHWNQQLGAFQKLILIKSFMEEKVVSAVTEFVITGLGQQFVEN--PPVDLTTLY-ADMSPSIPLVFILSTGSDPMGAFQRFANEKGYQDRVKSISLGQGQG-PIAERMIKEALKNGIWIFLQNCHLAVSWMLAMEELIKSFNEPDTVIHEDFRLFLSSMPTNVFPVTVLQNSVKVTNEPPKGLRANVRRAFTEISSTFFEEHILGRKWRKIIFGVCFFHAIIQERKKFGPLGWNIRYEFNDSDRECALLNLNLYCQTG----------HIPWDALTYITGEITYGGRVTDAWDQRCLRTILKSFFSLATLEEGYTY-----SKSGIYFAPDSDSLTEYKQYIEDLPLIDDPEVFGMHENANLAFQRQETMTVINTILEVQ----------------PRSSAAGGGK-SNDEVVHELVDSILAKIPDKLD-MDAAVESLFLQDPKGRVNSLTTVLGQEVDRFNFLLRVLKTSLCTLQKAIAGLVVMSEEMEKIYNSFLNNQVPDHWSNAAYPSLKPLGSWVRD--------LNLRTAFIESWITRGQPKSFWISGFFFPQGFLTGALQNHARKYNLPIDEL 4021
BLAST of Cytoplasmic dynein 1 heavy chain 1 vs. Ensembl Zebrafish
Match: dnah6 (dynein, axonemal, heavy chain 6 [Source:ZFIN;Acc:ZDB-GENE-030616-623]) HSP 1 Score: 1377.07 bits (3563), Expect = 0.000e+0 Identity = 943/3324 (28.37%), Postives = 1672/3324 (50.30%), Query Frame = 3 Query: 4101 VWNELKSIWEKIRDMKETPWLS-----VQPRKLRQDIENLTAQLKEL-----PNSFKQY--ASFEHVRTLLKMYMKVNASIVELKSEAIKERHWRMLMRKLNVSWSLNELQ-LGKVWDIDLVKNEEIIREVLAIAQGEKALEEYLRQITEVWKNYVLELTNYQSKSK--IIKGWDDLFNKVKEHINNVTSMKASPYFKQFEEEATAWEDRLNKINALFDVWIDVQRRWIYLDGIFAGSADIKVLLPVESQRFQSVSTEFLGLMKKVQKSPLVTDVLNIANVQRQLERLADLLGKIQKSLGEYLERQRSSFPRFYFVGDEDLLEIIGNSXXXXXXXXXXXXMFAGVHSIILSE--------DEKV--------ILGMMSKEGEELRFISPVSIIEHPRINDWLTAMEKEMRVSLAKYLNVAVKEISGWRTESNIDKDKFMVWL-DKYQAQIVVLAAQITWSEAVEASLASG----VSLESTMTVVHSTLNMLADTVLYEQPPVRRRKLEHLIIEYVHQRDVLRALHNDGVSSNKNFDWMSQMRFYFDPKQTDPLHQLSIHVANAKFHYGFEYLGVCDRLVQTPLTDRCYLTMTQALEARLGGSPFGPAGTGKTESVKSLGNQLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLSAVSQQIQGIQEALRELMVSKKDSINVELLGKQVHVNPDMAIFITMNPGYAGRSNLPDNLKKLFRSLAMTQPDRQLIAQVMLYSQGFRTAEVLAGKVVPFFKLCDEQLSPQSHYDFGLRALKSVLVSAGNVKRDRIKQEKEKIVARGEEINETAIAEQLPEQEILIQSVMETMVPKLIADDIPLLYSLLTDVFPGVEYRQAEMKRLREELRKVSENKFLVYSDEPNTAGYLWVEKVLQLYQITTIHHGLMMVGPSGSGKTMACRVLLQALENIDGIEGVAH-----------IIDPKSISKDSLYGYMDPNTREWTDGLFTHILRRIIDSVRGESNKRQWIVFDGDVDPEWVENLNSVLDDNKLLTLPNGERLAIPPNVRIMFEVQDLKYATLATVSRCGMVWFSEEVLTTGMILTHFLNELKKVQVMEGEEDFSVNQGDTGADADSKISSSPIIQLQTQVSSILAPFFTEDGLIAKCLDYSTTLEHIMDFTRLRALTSLFSMIKQSIRNMIEYNQSHSDFPLNNEQIENYVAKSLISSVVWSMSGDSKLKVREQLSQYIK----NISTVDLPTVGGIKNI-IDFEVNIQGTWVAWSNKVPQIEVETHKITATDVVVPTMDTVRHEALLYTWLAEHRPVLLCGPPGSGKTM---TLFSALRCLPDMEVVGLNFSSATTPELMLKTFDQYCEYRKTPNGIVLAPQQLNKWLIFFCDEINLPDMDKYGTQRVISFLRQMVEHHGFYRITDMQWVSFERIQFVGACNPPTDPGRKPLSHRFLRHVPVVYVDYPGETSLKQIYSTFNRAMLRMLPS-LRGYADTLTNAMVEFFLKTQERFTHDMQP-----HYIYSPREMTRWVRGIHEALKPLESLSVEGLVRIWAHEALRLFQDRLVEEDERHWTDDNINEVALKHFPNINKEEA--LKRPILYSNWLS-------KDYSAVT-----QEELRDYVKARLKVFYEEELDVPLVLFNQVLDHVLRIDRVFRQPQGHLLLIGVSGAGKTTLSRFVSWINGLSVFQVKVHNKYTAEDFDEDLRNVLRRSGCKGEKITFIMDESNVMDSSFLERMNTLLANGEVPGLFEGDELTTLMTQCKEGAIREGLMIDSQEELYKWFTQQICRNLHVVFTMNPSADGLKDKASTSPALFNRCVLNWFGDWSLEAYFQVGKEFTNRLDLERTDYKVPDTLPCIAEGLLPQNPIYRDVVVNALVFVHQTMHQANVRVQKRGGRTAAITPRHYLDLIAHYMKLSAEKRADLEEQQLHLNNGLKKIEQTVDQVEVMQRSLTKKRQELENMNEAANAKLKQMVQDQQEAEQKKTT---GQALKEELAKQEQFVNEKQKTVKQELDQVEPTVNEAKQAVQNIRKKDIQEIKAMKNPPNAVKMAVESICLLLGEKTTDWQSILKVIIKDTFVTSILNFNTDDVSDNTRETMKKKYLSNPDYNFEKVNKASNACGPMVKWVLAQISYADILKRVEPLRNELTELSDAAEQNRKKSQETEDLIAQLEKSIAKYTEEYATLISQAQTIKSDLASVESKVGRSVALLGSLSSERTRWDSGSETFKAQMATINGDCLLSSAFMAYGGYFDQHMRTSLFNTWCHHLSEADILFRSDLARVEYLSNPDDRLRWQANSLPADDLCVENAIILRRYNRYPLIIDPSGQATTFLLNEYKEKKITKTSFLDDSFRKTLESALRFGTPLLVQDV-ESYDPILNPVLNREVRRTGGRTLITLGDQDIDLSPTFTIFLSTRDPSVEFAPDICSRVTFVNFTVTRSSLQNQCLNAVLKIERPDIDQKRSDLLKAQGEFQLKLRHLEKDLLQSLNEAQGNLLENDKIIARLETLKREAADVAKKVEETDVVMQEVESVSTEYVPLAQSCSNIYFTLEAMNQIHFLYQYSLQLMLDIFSSVLINNPELTNVKAASDRLKIITKNLFQVTYNRLARGMLHEDQITFATILARIFLKGSTPIGFLENEFQHFLRSQEATITSSDSNKQDNLGLTLHQDQIDSVKRLK-KLKVFAKIEEKVKSTK---DIKNWTLTVTPE---SNVPELWVDDNNYNDEKLSKIAKGMYN--------LLIIQAIRPDRLLASTQKFIASVLGDTFTESVRGTLDLASIVEVEVTACVPILLCAVQGYDPSGRVEDLASEQGKQ--LTGIAIGSAEGFSQAEKAINSAAKTGKWVMLKNVHLATSWLVSLEKKIHSLQA-----HPNFRLFLTMEITPKLPVNLLRAGRVLVFEPPPGIKANLLRTLSSINNQRMSKEPVERS--RLYFLLAWLNAIVQERLRYVPLGYSKKYEFGESDFKCALDTIDTWVDGAAMGRTNLPPEKIPWVALQTLLGSCIYGGKIDNAFDQRLLNSFLGYLFTEKCFDHNFALVSDADDGSNIAF-PESTKHTDILQWVHKLPDLQTPSWLGLPNSAEKVLLTNLGQSLIGNILKMQQSLEDDEELVVGQSKTKRTIEVGDGRPAWMRQLYQSTQTWLQILPKSVTPLQRTIEN--IKDPMYR------CFEREVNSGCNLLASVRKDLEDVAEVCKGAKKPTNHHRSMMADLAKGIIPKMWIRYAIPPGLTVIQWIQDFADRIKQLLHISDTAAKSGVIALRSIQVWLGGLFMAEAYITATRQSVAQNNKWALEEL 13736 +W+ L+ WE + E WL + P L + + + +L PN+ + A E +R L + I +L++ +K RHW ML ++ S L E Q L + +ID+ + I+EV A GE +LE LR+I + WK + ++ I+ G DD+ + + I NV ++ +S Y + W+ +L N D W+ QR W+YL+ IF+ + DI+ LP E++ F V + +M+KV + P + + LL +IQK L YLE +R FPRFYF+ +++LLEI+ +++ + +Q H +K F + + + D+ V IL M+S EGE++ + + + DWL +E+ M SL + A I+ ++++ ++ W+ + +Q+V+ +Q+ W ++ L +L+ LN LA V P + R + LI VH RD++ L + V S+ NF+W Q+R+Y+D D + ++++ +++ YG+EYLG C RLV TPLTDRCYL + AL+ LGG+P GPAGTGKTE+ K L L +VFNC + D++ MG F GL Q GAW CFDEFNR+ +LS ++QQ+ I+ A +K E G+++ + A FITMNPGYAGR+ LPDNLK LFR +AM P+ LIA+V+LYS+GF +++ LA K+ +KLC EQLS Q HYDFG+RA+KSVLV AG++KR+ L E +LI+++ ++ +PK + DD L +L+D+FPGV + + L+ + + S +P + + KV+QLY+ + HG+M+VGP+GSGKT RVL L D + H +++PKS+S LYG ++P T EW DGL +R +V+ S+ +W++ DG VD W+EN+N+VLDDNK+L L N ER+ + P++ +MFEVQDL A+ ATVSRCGMV+ E L + +L + ++ + + + + + + +S +Q QV I+K LE + LFS S++ + + ++ N + ++ + +W++ G+ + +++ + + L +VG + ++ ++F++ W ++ + +I +++VPT DTVR+ L+ L+ + VL G G GK++ L ++++ V +NFS+ T+ + + E ++ I+ AP NK ++ F D++N+P +D YG+Q I LRQ + HGFY W + AC PP GR P++ RF+RH ++ + P E+SLKQI+ L + ++ AD++ +A VE + R + D+ P HY+++ R++++ V+G+ + +P + R++ HE R+F DRL+ +++ + + I+E+A K+F +IN E A + +PI++ +++ + Y +T ++ L+DY+ F +E LV F ++HV RI R+ RQ +G+ LL+GV G GK +L+R + + G FQ+++ Y + F EDLR + R +G +G+ + F+ ++ ++ FLE +N +L +GEVP LFE DEL ++ A G+ +++E+Y++F ++ LH+V M+P D + + P+L N C ++WF W EA V + F ++ + K C +E V +H ++ R R TP YL+LI Y+ + EKR L+ + + NGL K+ +T + V+ M++ L+ L + +A ++++ DQ+ A+Q + +AL + A++ Q + + +++LD+ P ++ A +A+ + K DI E++ PP+ V +E++C+LL KT DW S +++ F+ +++++ D++ + + K Y+SNPD+ EKV K S AC M WV A Y+ +LK V P R +L + +E ++ + ++E I +++ + +++ +T+ +A E+++GRS L +L E+ RW F+ ++ + G+ +++A +AY G F H R L + W I + + + L +P + +W A LP D++ EN I++ R R+PL+IDP QA ++ ++ + + D F +TLE+A+R G P+L++++ E+ DP L P+L ++ +GGRTLI LGD DID F +++T+ + + P++C +VT +NFTVT+S L++Q L+ V+++ERPD++++RS L+ + +L+ +E +L+ L ++GN+L+N++++ L+ K + + ++ E + + + +Y P+A S +YF + ++++I +YQ+SL+ +F++ I + E K S RL+I+ Y ++RG+ + + ++ +L + I + E+ +FLR I K + L+ ++ L+ +L F I++++ ST + +TV PE V +L EK ++ +G +N L++I++ ++++++ +F+ + LG F E+ +DLA++ +++ +P++ G DP G + A+E+G Q + I++G +G AE+ I A K G W+ L+N HLA SW++++E+ I S H +FRLFL+ T PV +L+ + EPP G++AN+ R + I++ + + R ++ F + + +AI+QER ++ PLG++ +YEF +SD +CAL ++ + IPW AL + G YGG++ +A+DQR L + L F+ + + S I F P+S T+ Q++ LP + P G+ +A ++I IL++Q R+ G G+ + +++ + L +P + + +E+ ++DP R +EV+ LL ++ L + + G + + +P W A P + W++D L++ +S + + W+ G F + ++T Q+ A+ ++EL Sbjct: 901 LWDSLEE-WESL----ENGWLQDKFDELDPELLSKQVNRFVKYVSQLEKGLPPNNVVPFLKAKVESMREKLPV-------ITDLRNPCLKARHWEMLEAIVD-SKLLEEAQTLATLQNIDIFRFGLQIQEVSGQASGEASLENILRKIEDSWKTTEFIVLPHRDTKDVFILGGTDDIQVLLDDSIVNVATVASSRYAGPIKARVDKWQRQLLLFNQTLDEWLLCQRSWLYLESIFS-APDIQRQLPAEAKMFLQVDKSWKEIMRKVNRMPNALRAATQTGILDVFQNNNALLERIQKCLEAYLESKRVIFPRFYFLSNDELLEILAQTRNPQAVQPHLRKCFDAISQLEFATLTPTTPEGDDTVEKIQYTNDILSMVSPEGEKV--VLGKGLKARGNVEDWLGKVEEAMFSSLRRLSKAA---IADYQSKPRVE------WVVAGHPSQVVLTISQLMWCRDMDNCLEGEHDHFQALQEFEITNFERLNALAALVRGNLPSLHRNIITALITIDVHARDIVTDLVKEQVDSSDNFEWQRQLRYYWDVDLDDCVARMAL----SQYIYGYEYLGACPRLVITPLTDRCYLCLMGALQLDLGGAPAGPAGTGKTETTKDLAKALAIQCVVFNCSDGLDYKMMGTFFSGLAQSGAWCCFDEFNRINIEVLSVIAQQLITIRNA----KAAKLSRFMFE--GREIKLVMTCAAFITMNPGYAGRTELPDNLKALFRPIAMMVPNYALIAEVILYSEGFESSKTLARKMTQMYKLCSEQLSQQDHYDFGMRAVKSVLVMAGSLKREN---------------------PNLSEDVVLIRALRDSNLPKFLKDDAALFSGILSDLFPGVTIPEHDYGVLQSTIH----SSLCQRSLQPLPS---IISKVIQLYETMLVRHGVMLVGPTGSGKTTVYRVLADTL---DTLHHAGHPNPFFRPVKTYVLNPKSVSMGELYGEVNPLTLEWRDGLMALCVRA---AVQDFSDDHKWVISDGPVDALWIENMNTVLDDNKMLCLANSERIKLTPSIHMMFEVQDLAVASPATVSRCGMVYIDPEELKWMPYVQTWLTGFAE-KISDPVRGYLMELFEQYVEKGLQFASKHCVQAVAQVD------------ISKVTTLCCLLEAL-----------LFSDGAPSLK-------------MESSKLNNVLCQTFVFCYLWAVGGNLIESHWDTFDTFVRQQFEDNTDAKLSSVGDLWSVYMNFDIKCLEPW----ERIIPVFSYNSEIPFFEMLVPTTDTVRYGYLMEKLLSVNHSVLFTGITGVGKSVVARALLNSVQEKAGYVPVYINFSAQTSSARTQEIIESKLEKKR--KNILGAPA--NKKIVVFVDDLNMPKLDSYGSQPPIELLRQFQDFHGFYDREKFFWKEIHDMTIAAACAPPGG-GRNPVTPRFIRHFSMLCLPTPSESSLKQIFKAILGGFLTEFSTAVKQAADSIVDAAVEIY----HRMSVDLLPTPAKSHYVFNLRDLSKCVQGMLQC-EPTTVRDQTHIFRLFCHECQRVFHDRLINNEDKSYFNTMISEMASKYF-SINIEPAYFVNQPIIFGDFIKVGADKADRVYEDLTDMDKIRQVLQDYLDDYNTTFAKE---TKLVFFQDAIEHVSRIARMIRQERGNALLVGVGGTGKQSLTRLAAHMCGYRCFQIELSRGYNYDSFHEDLRKLYRMAGVEGQDMVFLFTDTQIVVEEFLEDINNMLNSGEVPNLFEKDELKQVLAAISPKAKEAGISEGNRDEVYQFFITRVREKLHIVLCMSPVGDSFRSRCRMFPSLVNCCTIDWFVQWPREALLSVSQTFFQNVEFGSEEMK-----QCFSE---------------MCVEIHVSVTDMAERFYSELRRHYYTTPTSYLELINLYLGMLGEKRQQLQAARDRIKNGLTKLLETNELVDKMKQDLSALEPVLAQKSIDVSALMEKLAVDQENADQVRRVVKEDEALAKVKAEETQAIADD---AQRDLDEALPALDSANKALNALDKADISEMRVFTKPPDLVMTVMEAVCILLSNKT-DWASAKQLLGDGNFLKKLMDYDKDNIKPQILQKLHK-YISNPDFVPEKVEKVSKACKSMCMWVRAMDLYSRVLKEVGPKREKLAAAQVELDATMSTLKEKQNKLQEVENQIKVLQDQFESSMAEKETLAKTMALTEARLGRSGKLTSALGDEQVRWQESITLFEQEIHNVIGNVFIAAACVAYYGAFTSHYRQLLIDHWITRCQSLGIPISDNFSLIGILGDPYEIRQWNAEGLPRDNVSTENGILVMRGRRWPLMIDPQDQANRWIRSKETKNGLKVIKLTDAGFLRTLENAIRLGMPVLLEELKETLDPALEPILLKQTFVSGGRTLIRLGDSDIDYDKNFRFYMTTKMANPHYLPEVCIKVTIINFTVTKSGLEDQILSDVVRLERPDLEEQRSQLIVRINADRNQLKAIEDRILKLLFTSEGNILDNEELVQTLQESKVTSQAIKSRLVEAETTEEMINRAREKYRPVATRGSIMYFVIASLSEIDPMYQFSLKYFKQLFNNT-IESAE--KHKDLSLRLQILLDQTLLSAYTNVSRGLFEQHKAIYSFMLCVEIMMQRGEIS--QQEWLYFLRGA-GGIRKELPEKPEVPWLS--DFAWETCCNLEDRLPCFNGIKKEIISTPISVKLGQLEVTVNPEHWDGYVTDLPPFSEEIPSEKQPQV-RGHWNQQLGAFQKLILIKSFMEEKVVSAVTEFVITGLGQQFVEN--PLVDLATLY-ADMSPSIPLVFILSTGSDPMGAFQRFANEKGYQDRVKSISLGQGQG-PIAERMIKEALKNGIWIFLQNCHLAVSWMLAMEELIKSFNEPDTVIHEDFRLFLSSMPTNVFPVTVLQNSVKVTNEPPKGLRANVRRAFTEISSTFFEEHILGRKWRKIIFGVCFFHAIIQERKKFGPLGWNIRYEFNDSDRECALLNLNLYCQTG----------HIPWDALTYITGEITYGGRVTDAWDQRCLRTILKSFFSLATLEEGYTY-----SKSGIYFAPDSDSLTEYKQYIEDLPLIDDPEVFGMHENANLAFQRQETMTVINTILEVQ----------------PRSSAAGGGK-SNDEVVHELADSILAKIPDKLD-MDAAVESLFLQDPKGRVNSLTTVLGQEVDRFNFLLRVLKTSLCTLQKAIAGLVVMSEEMEKIYNSFLNNQVPDHWSNAAYPSLKPLGSWVRD--------LNLRTAFIESWITRGQPKSFWISGFFFPQGFLTGALQNHARKYNLPIDEL 4021
BLAST of Cytoplasmic dynein 1 heavy chain 1 vs. Ensembl Xenopus
Match: thumpd2 (THUMP domain containing 2 [Source:Xenbase;Acc:XB-GENE-965047]) HSP 1 Score: 6126.59 bits (15893), Expect = 0.000e+0 Identity = 2977/4676 (63.67%), Postives = 3687/4676 (78.85%), Query Frame = 3 Query: 93 DITANL-VQPPDQEITAIS-LPKFIKYLTLYAFPCMLNDDESKSRKDYELFLSEPQNEECLTKFINDNQVTTLTIQQ-TKRXXXXXXXXXXXXKISNEVNFESN---KSQTSIFIKNNQVIEADKTISSQLQVLSYCDGPPFETMHSLVCYGLLPYFXXXXXXXXXXXXXXXXXMVPSVEKKIAELEIGLLHLQQNIEIPEITLTPHPYVAHIIQEKLLQNKEARVSDFEDKFEDTQFLNQLQAGVNRWIKEIQKVTKLNRDPSTGTALQEISFWLNLEHSLDKIQEKRESLEVALTLAILKQAKRFHATTSFDTDTALSSAKIQVKDYNQLMKDFPINDLLSASQLDKISEALQQIFSHLKKVRATKYPVNRIIKLMEALSRDLTTQLMKVISNMHLMSMPYDEFEKIFTACQQVFSTWEDEYDKMQNLLRDIAKKKREEFTKFAWKMNATHKKLQTRLENIKKFRYQHEQLRQVIVRVLKP-VTKVVPSVEAGVPKDQITDKGDKSSTFLPESADTSSIDEVNAAYEIVKVIDCLDFAKEENDEWDAAIKRYEERIDRVESRIASHLRDLLGQSKNANEMFRYFSRFNALFVRPHIRGAIGEYQTQLIQRVKDDIEALHNKFKVQYASSTACKMSKVRDLPPVSGSIIWVRQILRQLNAYMKRVEDVLGKDWAQHIEGQKLKADGESFKLKLNTSELFEEWSKKVAEKSLSVAGSIFNVESTRTVVTVRDREPQKITVLKLKVNFLPDVITLAKEVRNMRALGFRTPLSIVNKAHSANQLYPFAISLIESVRTYESTCSKIEEHKMQNISLLTAGLRKDVQLCIHEGVQITWESYRLDQYVQKLAELVFSFQEKVDDLVIVIKEIDFNVKALETCSYNKQTFEEILIRIQEAVDNMSLHQFSNLAQWVSNLDSLVEQRLIVRLEAGLLEWIKVLKGXXXXXXXXXXXXXXXVNSMAKHRLGGKPQIKKLIHELRITNQQMHLYPSIEVATQDILYQMSSWQNIILNLSRIVHSRYQVGLETE-SDNQKTYKKLLSSLPNSGESLENAYAAVHNILRDANEYVKTWTNYQSLWDLQGDQLFSLIADDNTVWMNVLEEIKSMRKHFDVAETQKEFGPLVIAFGKVQSKVSMKYDNWHKEVLTKFGQNMGKMMTTLYNEVQRARNELEQQSIDSGGTNESVNFITYTQNIKRKMNTWEKQAEACRAGQNILCRDRFQFPNDWLDSENIQGEWSAFKEIMRRKQETISSQVASLQMKITEEDKIVESKTTEVLGNWEKDKPIAGDLTPEEAVNIIQILEGKFNRLKEERENVQKAKEALELTEIGVKPISEEKVTNALSELHDLKNVWNELKSIWEKIRDMKETPWLSVQPRKLRQDIENLTAQLKELPNSFKQYASFEHVRTLLKMYMKVNASIVELKSEAIKERHWRMLMRKLNVSWSLNELQLGKVWDIDLVKNEEIIREVLAIAQGEKALEEYLRQITEVWKNYVLELTNYQSKSKIIKGWDDLFNKVKEHINNVTSMKASPYFKQFEEEATAWEDRLNKINALFDVWIDVQRRWIYLDGIFAGSADIKVLLPVESQRFQSVSTEFLGLMKKVQKSPLVTDVLNIANVQRQLERLADLLGKIQKSLGEYLERQRSSFPRFYFVGDEDLLEIIGNSXXXXXXXXXXXXMFAGVHSIILSEDEKVILGMMSKEGEELRFISPVSIIEHPRINDWLTAMEKEMRVSLAKYLNVAVKEISGWRTESNIDKDKFMVWLDKYQAQIVVLAAQITWSEAVEASLASGV-------SLESTMTVVHSTLNMLADTVLYEQPPVRRRKLEHLIIEYVHQRDVLRALHNDGVSSNKNFDWMSQMRFYFDPKQTDPLHQLSIHVANAKFHYGFEYLGVCDRLVQTPLTDRCYLTMTQALEARLGGSPFGPAGTGKTESVKSLGNQLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLSAVSQQIQGIQEALRELMVSKKD---SINVELLGKQVHVNPDMAIFITMNPGYAGRSNLPDNLKKLFRSLAMTQPDRQLIAQVMLYSQGFRTAEVLAGKVVPFFKLCDEQLSPQSHYDFGLRALKSVLVSAGNVKRDRIKQEKEKIVARGEEINETAIAEQLPEQEILIQSVMETMVPKLIADDIPLLYSLLTDVFPGVEYRQAEMKRLREELRKVSENKFLVYSDEPNTAGYLWVEKVLQLYQITTIHHGLMMVGPSGSGKTMACRVLLQALENIDGIEGVAHIIDPKSISKDSLYGYMDPNTREWTDGLFTHILRRIIDSVRGESNKRQWIVFDGDVDPEWVENLNSVLDDNKLLTLPNGERLAIPPNVRIMFEVQDLKYATLATVSRCGMVWFSEEVLTTGMILTHFLNELKKVQVMEGEEDFSVNQGDTGADADSKISSSPIIQLQTQVSSILAPFFTEDGLIAKCLDYSTTLEHIMDFTRLRALTSLFSMIKQSIRNMIEYNQSHSDFPLNNEQIENYVAKSLISSVVWSMSGDSKLKVREQLSQYIKNISTVDLPTVGGIKNIIDFEVNIQGTWVAWSNKVPQIEVETHKITATDVVVPTMDTVRHEALLYTWLAEHRPVLLCGPPGSGKTMTLFSALRCLPDMEVVGLNFSSATTPELMLKTFDQYCEYRKTPNGIVLAPQQLNKWLIFFCDEINLPDMDKYGTQRVISFLRQMVEHHGFYRITDMQWVSFERIQFVGACNPPTDPGRKPLSHRFLRHVPVVYVDYPGETSLKQIYSTFNRAMLRMLPSLRGYADTLTNAMVEFFLKTQERFTHDMQPHYIYSPREMTRWVRGIHEALKPLESLSVEGLVRIWAHEALRLFQDRLVEEDERHWTDDNINEVALKHFPNINKEEALKRPILYSNWLSKDYSAVTQEELRDYVKARLKVFYEEELDVPLVLFNQVLDHVLRIDRVFRQPQGHLLLIGVSGAGKTTLSRFVSWINGLSVFQVKVHNKYTAEDFDEDLRNVLRRSGCKGEKITFIMDESNVMDSSFLERMNTLLANGEVPGLFEGDELTTLMTQCKEGAIREGLMIDSQEELYKWFTQQICRNLHVVFTMNPSADGLKDKASTSPALFNRCVLNWFGDWSLEAYFQVGKEFTNRLDLERTDYKVPDTLPCIAEGLLPQNPIYRDVVVNALVFVHQTMHQANVRVQKRGGRTAAITPRHYLDLIAHYMKLSAEKRADLEEQQLHLNNGLKKIEQTVDQVEVMQRSLTKKRQELENMNEAANAKLKQMVQDQQEAEQKKTTGQALKEELAKQEQFVNEKQKTVKQELDQVEPTVNEAKQAVQNIRKKDIQEIKAMKNPPNAVKMAVESICLLLGEKTTDWQSILKVIIKDTFVTSILNFNTDDVSDNTRETMKKKYLSNPDYNFEKVNKASNACGPMVKWVLAQISYADILKRVEPLRNELTELSDAAEQNRKKSQETEDLIAQLEKSIAKYTEEYATLISQAQTIKSDLASVESKVGRSVALLGSLSSERTRWDSGSETFKAQMATINGDCLLSSAFMAYGGYFDQHMRTSLFNTWCHHLSEADILFRSDLARVEYLSNPDDRLRWQANSLPADDLCVENAIILRRYNRYPLIIDPSGQATTFLLNEYKEKKITKTSFLDDSFRKTLESALRFGTPLLVQDVESYDPILNPVLNREVRRTGGRTLITLGDQDIDLSPTFTIFLSTRDPSVEFAPDICSRVTFVNFTVTRSSLQNQCLNAVLKIERPDIDQKRSDLLKAQGEFQLKLRHLEKDLLQSLNEAQGNLLENDKIIARLETLKREAADVAKKVEETDVVMQEVESVSTEYVPLAQSCSNIYFTLEAMNQIHFLYQYSLQLMLDIFSSVLINNPELTNVKAASDRLKIITKNLFQVTYNRLARGMLHEDQITFATILARIFLKGSTPIGFLENEFQHFLRSQEATITSSDSNKQDNLGLTLHQDQIDSVKRLKKLKVFAKIEEKVKSTKDIKNWTLTVTPESNVPELWVDDNNYNDEKLSKIAKGMYNLLIIQAIRPDRLLASTQKFIASVLGDTFTESVRGTLDLASIVEVEVTACVPILLCAVQGYDPSGRVEDLASEQGKQLTGIAIGSAEGFSQAEKAINSAAKTGKWVMLKNVHLATSWLVSLEKKIHSLQAHPNFRLFLTMEITPKLPVNLLRAGRVLVFEPPPGIKANLLRTLSSINNQRMSKEPVERSRLYFLLAWLNAIVQERLRYVPLGYSKKYEFGESDFKCALDTIDTWVDGAAMGRTNLPPEKIPWVALQTLLGSCIYGGKIDNAFDQRLLNSFLGYLFTEKCFDHNFALVSDADDGSNIAFPESTKHTDILQWVHKLPDLQTPSWLGLPNSAEKVLLTNLGQSLIGNILKMQQSLEDDEELVVGQS-KTKRTIEVGDGRPAWMRQLYQSTQTWLQILPKSVTPLQRTIENIKDPMYRCFEREVNSGCNLLASVRKDLEDVAEVCKGAKKPTNHHRSMMADLAKGIIPKMWIRYAIPPGLTVIQWIQDFADRIKQLLHISDTAAKSGVIALRSIQVWLGGLFMAEAYITATRQSVAQNNKWALEELFLDVELGEGK---VDSNTCVITGLRLMGSEIVDPRTLKLSTLIYKDIDICRLKWIRVEKSQQLEGSSAKDKVCLPIYLNAARSTVLFTLYF--STTDSSYDFYKRGVAI 14048 D +ANL V Q + S L K I+ L P +L +D ++ E L E E + KF++D Q+ T+ +++ T +E+ E IS V+ + + KS + FIK VI+ADK ISSQL+VL+ + P+ET+HS + + P+FKSYI++ GK M PSVEKKIAELE+GLLHLQQNIEIPEI+L HP + ++ ++ + ++ +V+DF DK ED FLNQLQ+GVNRWI+EIQKVTKL+RDP++GTALQEISFWLNLE +L +IQEKRES EV LTL ILK KRFHAT SFDTDT L A V DYN LMKDFP+NDLLSA++LDKI +AL IF+HL+K+R TKYP+ R ++L+EA+SRDL++QL+KV+ LM + Y+EFEK+ AC +VF TW+DEY+K+Q LLRDI K+KREE K W++N H+KLQ RL+ ++KFR QHEQLR VIVRVL+P VT V + VP+ Q K + L ++AD ++I+EVN AYE VK +D LD +KE + W+AA+KRY+ERIDRVE+RI + LRD LG +KNANEMFR FSRFNALFVRPHIRGAI EYQTQLIQRVKDDIE+LH+KFKVQY S ACKMS VRDLPPVSGSIIW +QI RQL AYMKRVEDVLGK W H+EGQKLK DG+SF++KLNT E+F++W++KV +++L V+G IF +ESTR R R VLKLKVNFLP++ITL+KEVRN++ LGFR PL+IVNKAH ANQLYPFAISLIESVRTYE TC K+EE +ISLL AGL+K+VQ I EG+ + WESY+LD YVQ+LAE VF+FQEKVDDL+I+ ++ID V++LETC Y+ +TF EIL R+Q+AVD+++LH +SNL WV+ LD +E+ L RL+AGL W VL G++ + + D DTD H+ GG+P+IK ++HELRITNQ ++L P IE + +M SW+ +IL+L RI RYQVG+ E S+ +K Y+ L+ +P+ SLE AY+AV I+ + +YVK W YQ LWD+Q + +++ + +D W +L +I+ R FD AET+KEFGP++I +GKVQSKV++KYD+WHKEVL+KFGQ +G+ MT ++++ ++R ELEQ S+D+ T+++V FITY Q++KRK+ +EKQ + R GQ +L + RFQFP+ WL +NI+GEW AF +IMRRK I QVA+LQMKI +ED+ VES+T ++L +WEK KP+AG+L PEEA+ + I EGKF RLK++RE KAKEALELT+ G+ SEE+V AL EL DLK VW+EL +WE+I MKE PW+SVQPRKLRQ+++ L QLK P +QYAS+E+V+ LLK YMKVN ++ELKSEA+K+RHW+ LM++L+V+W ++EL LG++WD+DL +NE I+++VL +AQGE ALEE+L+QI EVW Y L+L NYQ+K ++I+GWDDLFNKVKEHIN+V++MK SPY+K FEE+A +WED+LN+I ALFDVWIDVQRRW+YL+GIF GSADIK LLPVE+QRFQS+STEFL LMKKV KSPLV DVLNI VQR LERLADLLGKIQK+LGEYLER+RSSFPRFYFVGDEDLLEIIGNSK++ KLQKHFKKMFAGV SIIL+ED V+LG+ S+EGEE+ F +PVSI EHP+IN+WLT +EKEMRV+LAK L +V E+ + ++ID ++ W+DKYQAQ+VVL+AQI WSE VE++L+S L+S T V +TLN+LAD+VL EQPP+RRRKLEHLI E VHQRDV R L + S K+F+W+SQMRFYFDPKQTD L QLSI +ANAKF+YGFEYLGV D+LVQTPLTDRCYLTMTQALEARLGGSPFGPAGTGKTESVK+LG+QLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLSAVSQQ+Q IQEALRE +D +I ELL KQV V+PDMAIFITMNPGYAGRSNLPDNLKKLFRSLAMT+PDRQLIAQVMLYSQGFRTAEVLA K+VPFFKLCDEQLS QSHYDFGLRALKSVLVSAGNVKR+RI++ K++ RGE ++E +AE LPEQEILIQSV ETMVPKL+A+DIPLL+SLL+DVFPGV+Y + EM LREEL+KV + +L Y D G +WVEKVLQLYQIT I+HGLMMVGPSGSGK+MA RVLL+ALE ++G+EGVAHIIDPK+ISKD LYG +DPNTREWTDGLFTH+LR+IID+VRGE KRQWI+FDGDVDPEWVENLNSVLDDNKLLTLPNGERL++PPNVRIMFEVQDLKYATLATVSRCGMVWFSE+VL+T MI +FL ++ + + EGE++ + G + + + SSSP++Q+Q +++L P+FT +GL+ K L+++ LEHIMD TRLR L SLFSM+ Q+ RN+ +YN +H DFP+ +Q+E Y+ + LI +++WS SGD +LK+R +L +YI+ I+TV LP+ I IID+EV+I G W W KVPQIEVETHK+ A DVVVPT+DTVRHEALLYTWLAEH+P++LCGPPGSGKTMTLFSALR LPDMEVVGLNFSSATTPEL+LKTFD YCEYR+TPNG+VLAP QL KWL+ FCDEINLPDMDKYGTQRVISF+RQMVEH GFYR +D WV ERIQFVGACNPPTDPGRKPLSHRFLRHVPVVYVDYPG SL QIY TFNRAMLR++PSLR YA+ LT AMVEF+ +QERFT D+QPHYIYSPREMTRWVRGI EAL+PLE+L VEGL+RIWAHEALRLFQDRLVE++ER WTD+NI+ VALKHFPN+ K++AL RPILYSNWLSKDY V QEELRDYVKARLKVFYEEELDVPLVLFN+VLDHVLRIDR+FRQPQGHLLLIGVSGAGKTTLSRFV+W+NGLSV+Q+KVH KYT EDFDEDLR VLRRSGCK EKI FIMDESNV+DS FLERMNTLLANGEVPGLFEGDE TLMTQCKEGA +EGLM+DS EELYKWFT Q+ RNLHVVFTMNPS++GLKD+A+TSPALFNRCVLNWFGDWS EA +QVGKEFT+++DLE+ +Y VPD +P + + LPQ P +R+ +VN VFVHQT+HQAN R+ KRGGRT AITPRHYLD I HY L EKR++LEEQQ+HLN GL+KI++TVDQVE ++R L K QELE N A K +M++D K Q ++E+L KQ+ + +KQ +VK++LDQVEP V EA+ AV +I++ + E+KAM NPP AVK+A+ESICLLLGE+ TDW+ I V ++D F+++I+NFNT+D+SD RE MKK YLSNP +N+E VN+AS ACGPMVKW +AQ++YAD+LKRVEPLRNEL +L D A+ N++K+ E E +I LE SIA+Y EEYA LIS+AQ IK+DLA+VE+KV RS ALL SLS+ER RW+ SETFK QM+TI GDCLLS+AF+AY GYFDQ MR +LF TW HHL +A++ FR+D+AR EYLSN D+RLRWQANSLPADDLC ENAI+L+R+NRYPLIIDPSGQAT F++NEYK++KIT+TSFLDD+FRK LESALRFG PLLVQDVESYDPILNPVLNREVRRTGGR LITLGDQDIDLSP+F IFLSTRDP+VEF PD+CSRVTFVNFTVTRSSLQ+QCLN VLK ERPD+D+KRSDLLK QGEFQL+LR LEK LLQ+LNE +G +L++D II LE LK+EAA+V +KVEETD+VMQEVESVS +Y+PL+ +CS+IYFT+E++ QIHFLYQYSLQ LDI+ +VL N L + RL +ITK+LFQV +NR+ARGMLH+D ITFA +LARI LKG+ + EFQHFLR ++ + S+ K GLT ++Q++++ RL L F + KV++ + W + +PE VP +W + D+ + I + ++ LL+IQA RPDRLLA F+++VLGD+F + +DLA IV+ EV P+L+C+V GYD SGRVEDLA+EQ Q+T IAIGSAEGF+QAEKAIN+A K+G+WVMLKNVHLA WL+ LEKK+HSLQ H FRLFLTMEI PK+PVNLLRAGR+ VFEPPPG+KAN+LRT SSI R+ K P ER+RLYFLLAW +AI+QERLRY PLG+SKKYEFGESD + A DT+DTW+D A GR N+ P+KIPW AL+TL+ IYGG+IDN FDQRLLN+FL LFT FD F L D +I P+ + + +QWV LPD QTPSWLGLPN+AE+VLLT G +IG +LKMQ LED+++L ++ K +RT DGRPAWMR L+ + WLQ++P+++ L+RT+ENIKDP++R FEREV G LL VR+DL DV +VC+G KK TN+ R+++ +L KGI+P W R+ +P GLTVIQW+ DF++R+KQL +IS AA G L+++ VW+GGLF+ EAYITATRQ VAQ N W+LEEL L+V + + +D+ + +TGL+L G+ + + L LS I + I +L+W ++Q + V LP+YLN R+ ++FT+ F +T + + FY+RGVAI Sbjct: 9 DSSANLEVSAAVQNVADTSVLQKHIRKLV----PLLL-EDGGETPASLESALEEKSALEQMRKFLSDPQIHTILVERSTLKEDVGDEGEEEKEFISYNVSIDIHYGMKSNSLAFIKRTLVIDADKPISSQLRVLTLSEDSPYETLHSFISNAVGPFFKSYIRESGKADRDGDK-MAPSVEKKIAELEMGLLHLQQNIEIPEISLLIHPNITNVAKQCYERGEKPKVTDFGDKVEDPTFLNQLQSGVNRWIREIQKVTKLDRDPASGTALQEISFWLNLERALYRIQEKRESPEVLLTLDILKHGKRFHATVSFDTDTGLKQALETVNDYNPLMKDFPLNDLLSATELDKIRQALVAIFTHLRKIRNTKYPIQRALRLVEAISRDLSSQLLKVLGTRKLMHVAYEEFEKVMVACFEVFQTWDDEYEKLQVLLRDIVKRKREENLKMVWRINPAHRKLQARLDQMRKFRRQHEQLRAVIVRVLRPQVTAVAQQNQGEVPEPQDM----KVAEVLFDAADANAIEEVNLAYENVKEVDGLDVSKEGTEAWEAALKRYDERIDRVETRITARLRDQLGTAKNANEMFRIFSRFNALFVRPHIRGAIREYQTQLIQRVKDDIESLHDKFKVQYPQSQACKMSHVRDLPPVSGSIIWAKQIDRQLTAYMKRVEDVLGKGWENHVEGQKLKQDGDSFRMKLNTQEIFDDWARKVQQRNLGVSGRIFTIESTRA----RGRTG---NVLKLKVNFLPEIITLSKEVRNLKWLGFRVPLAIVNKAHQANQLYPFAISLIESVRTYERTCEKVEERN--SISLLVAGLKKEVQALIAEGIALVWESYKLDPYVQRLAETVFNFQEKVDDLLIIEEKIDLEVRSLETCMYDHKTFSEILNRVQKAVDDLNLHSYSNLPIWVNKLDMEIERILGGRLQAGLKTWTLVLMGQSDDKADVDMDTDA---PQVSHKPGGEPKIKNVVHELRITNQVIYLNPPIEDCRYKLYQEMFSWKMVILSLPRIQSQRYQVGVHYELSEEEKYYRNALTRMPDGPASLEEAYSAVMGIVTEVEQYVKVWLQYQCLWDMQAENIYNRLGEDLNKWQALLVQIRKARGTFDNAETRKEFGPVIIDYGKVQSKVNLKYDSWHKEVLSKFGQMLGQNMTEFHSQISKSRQELEQHSVDTASTSDAVTFITYVQSLKRKIKQFEKQVDLYRNGQRLLEKQRFQFPSSWLYIDNIEGEWGAFNDIMRRKDSAIQQQVANLQMKIVQEDRAVESRTIDLLTDWEKTKPVAGNLRPEEALQALTIYEGKFGRLKDDREKCAKAKEALELTDTGLLSGSEERVQVALEELQDLKGVWSELSKVWEQIDQMKEQPWVSVQPRKLRQNLDGLLNQLKNFPARLRQYASYEYVQRLLKGYMKVNMLVIELKSEALKDRHWKQLMKRLHVNWVVSELTLGQIWDVDLQRNEAIVKDVLLVAQGEMALEEFLKQIREVWNAYELDLVNYQNKCRLIRGWDDLFNKVKEHINSVSAMKLSPYYKVFEEDALSWEDKLNRIMALFDVWIDVQRRWVYLEGIFTGSADIKHLLPVETQRFQSISTEFLALMKKVTKSPLVMDVLNIQGVQRSLERLADLLGKIQKALGEYLERERSSFPRFYFVGDEDLLEIIGNSKNVAKLQKHFKKMFAGVSSIILNEDSSVVLGISSREGEEVIFKTPVSITEHPKINEWLTLVEKEMRVTLAKLLAESVTEVEIFGKSTSIDPATYITWIDKYQAQLVVLSAQIAWSENVESALSSAAVGGGDSSPLQSVQTNVEATLNVLADSVLMEQPPLRRRKLEHLITELVHQRDVTRTLMKIKIDS-KSFEWLSQMRFYFDPKQTDVLQQLSIQMANAKFNYGFEYLGVQDKLVQTPLTDRCYLTMTQALEARLGGSPFGPAGTGKTESVKALGHQLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLSAVSQQVQCIQEALREHSNPNRDKTHTITCELLNKQVKVSPDMAIFITMNPGYAGRSNLPDNLKKLFRSLAMTKPDRQLIAQVMLYSQGFRTAEVLANKIVPFFKLCDEQLSSQSHYDFGLRALKSVLVSAGNVKRERIQKIKKEKQERGEVVDEGEVAENLPEQEILIQSVCETMVPKLVAEDIPLLFSLLSDVFPGVQYHRGEMTALREELKKVCQEMYLTYGDGEEVGG-MWVEKVLQLYQITQINHGLMMVGPSGSGKSMAWRVLLKALERLEGVEGVAHIIDPKAISKDHLYGTLDPNTREWTDGLFTHVLRKIIDNVRGELQKRQWIIFDGDVDPEWVENLNSVLDDNKLLTLPNGERLSLPPNVRIMFEVQDLKYATLATVSRCGMVWFSEDVLSTDMIFNNFLARMRSIPLDEGEDE--AQRRRKGIEDEGEESSSPMLQIQRDAATVLQPYFTSNGLVIKALEHAFKLEHIMDLTRLRCLGSLFSMLHQACRNIAQYNANHPDFPMQIDQLERYIQRYLIYAILWSFSGDGRLKMRAELGEYIRRITTVPLPSAPNIP-IIDYEVSITGEWQPWQCKVPQIEVETHKVAAPDVVVPTLDTVRHEALLYTWLAEHKPLVLCGPPGSGKTMTLFSALRALPDMEVVGLNFSSATTPELLLKTFDHYCEYRRTPNGVVLAPVQLGKWLVLFCDEINLPDMDKYGTQRVISFIRQMVEHGGFYRTSDQTWVKLERIQFVGACNPPTDPGRKPLSHRFLRHVPVVYVDYPGPASLTQIYGTFNRAMLRLIPSLRTYAEPLTAAMVEFYTMSQERFTQDIQPHYIYSPREMTRWVRGIFEALRPLETLPVEGLIRIWAHEALRLFQDRLVEDEERRWTDENIDTVALKHFPNVEKDKALNRPILYSNWLSKDYIPVDQEELRDYVKARLKVFYEEELDVPLVLFNEVLDHVLRIDRIFRQPQGHLLLIGVSGAGKTTLSRFVAWMNGLSVYQIKVHRKYTGEDFDEDLRTVLRRSGCKNEKIAFIMDESNVLDSGFLERMNTLLANGEVPGLFEGDEYATLMTQCKEGAQKEGLMLDSHEELYKWFTSQVIRNLHVVFTMNPSSEGLKDRAATSPALFNRCVLNWFGDWSTEALYQVGKEFTSKMDLEKPNYIVPDYMPVVYDK-LPQPPSHREAIVNGCVFVHQTLHQANARLAKRGGRTMAITPRHYLDFINHYADLFNEKRSELEEQQMHLNVGLRKIKETVDQVEELRRDLRIKSQELEVKNAAEKTKTHKMLKD-------KVMSQEIQEQLHKQQAIIADKQMSVKEDLDQVEPAVIEAQNAVSSIKRHHLVEVKAMANPPAAVKLALESICLLLGEEMTDWKKIRTVFLRDNFISNIINFNTEDLSDAIREKMKKNYLSNPSFNYELVNRASLACGPMVKWAIAQLNYADMLKRVEPLRNELQKLEDDAKDNQQKANEVEQMIRDLEASIARYKEEYAVLISEAQAIKADLAAVEAKVNRSTALLKSLSAERDRWEKTSETFKNQMSTIAGDCLLSAAFIAYAGYFDQQMRQNLFTTWSHHLQQANVQFRTDIARTEYLSNADERLRWQANSLPADDLCTENAIMLKRFNRYPLIIDPSGQATEFIMNEYKDRKITRTSFLDDAFRKNLESALRFGNPLLVQDVESYDPILNPVLNREVRRTGGRVLITLGDQDIDLSPSFVIFLSTRDPTVEFPPDLCSRVTFVNFTVTRSSLQSQCLNEVLKAERPDVDEKRSDLLKLQGEFQLRLRQLEKSLLQALNEVKGRILDDDTIITTLENLKKEAAEVTRKVEETDIVMQEVESVSHQYLPLSTACSSIYFTMESLKQIHFLYQYSLQFFLDIYHTVLYENANLKGTIDHTQRLSVITKDLFQVAFNRVARGMLHQDHITFAMLLARIKLKGTIGEPAYDLEFQHFLRGKQIVLGSTFVPKIS--GLT--EEQVEAMMRLSNLSAFKDVISKVEADEQFCIWLDSSSPEQTVPYIWSE-----DKPATPIGQAVHRLLLIQAFRPDRLLAMAHIFVSTVLGDSFMSIIDQPIDLAHIVDTEVKPNTPVLMCSVPGYDASGRVEDLAAEQNTQITSIAIGSAEGFNQAEKAINTAVKSGRWVMLKNVHLAPGWLMQLEKKLHSLQPHACFRLFLTMEINPKVPVNLLRAGRIFVFEPPPGVKANMLRTFSSIPVSRICKSPNERARLYFLLAWFHAIIQERLRYAPLGWSKKYEFGESDLRSACDTVDTWLDDTAKGRQNISPDKIPWSALKTLMAQSIYGGRIDNEFDQRLLNTFLERLFTTSSFDSEFKLACKVDGHKDIQMPDGIRRDEFVQWVETLPDTQTPSWLGLPNNAERVLLTTQGIDMIGKMLKMQM-LEDEDDLAYAETEKKQRTDSTSDGRPAWMRTLHITACNWLQVIPQALNHLKRTVENIKDPLFRFFEREVKMGAKLLHDVRQDLTDVVQVCEGKKKQTNYLRTLINELVKGILPHSWSRFTVPAGLTVIQWVADFSERVKQLQNISQAAANGGAKELKNLHVWIGGLFVPEAYITATRQYVAQANSWSLEELCLEVSVTTVQNTVLDAYSFGVTGLKLQGATCTNNK-LSLSNAISTVLPITQLRW-----TKQTHTEKKANVVTLPVYLNFTRADLIFTVDFEIATKEDPHSFYERGVAI 4633
BLAST of Cytoplasmic dynein 1 heavy chain 1 vs. Ensembl Xenopus
Match: thumpd2 (THUMP domain containing 2 [Source:Xenbase;Acc:XB-GENE-965047]) HSP 1 Score: 6122.35 bits (15882), Expect = 0.000e+0 Identity = 2973/4676 (63.58%), Postives = 3688/4676 (78.87%), Query Frame = 3 Query: 93 DITANL-VQPPDQEITAIS-LPKFIKYLTLYAFPCMLNDDESKSRKDYELFLSEPQNEECLTKFINDNQVTTLTIQQ-TKRXXXXXXXXXXXXKISNEVNFESN---KSQTSIFIKNNQVIEADKTISSQLQVLSYCDGPPFETMHSLVCYGLLPYFXXXXXXXXXXXXXXXXXMVPSVEKKIAELEIGLLHLQQNIEIPEITLTPHPYVAHIIQEKLLQNKEARVSDFEDKFEDTQFLNQLQAGVNRWIKEIQKVTKLNRDPSTGTALQEISFWLNLEHSLDKIQEKRESLEVALTLAILKQAKRFHATTSFDTDTALSSAKIQVKDYNQLMKDFPINDLLSASQLDKISEALQQIFSHLKKVRATKYPVNRIIKLMEALSRDLTTQLMKVISNMHLMSMPYDEFEKIFTACQQVFSTWEDEYDKMQNLLRDIAKKKREEFTKFAWKMNATHKKLQTRLENIKKFRYQHEQLRQVIVRVLKP-VTKVVPSVEAGVPKDQITDKGDKSSTFLPESADTSSIDEVNAAYEIVKVIDCLDFAKEENDEWDAAIKRYEERIDRVESRIASHLRDLLGQSKNANEMFRYFSRFNALFVRPHIRGAIGEYQTQLIQRVKDDIEALHNKFKVQYASSTACKMSKVRDLPPVSGSIIWVRQILRQLNAYMKRVEDVLGKDWAQHIEGQKLKADGESFKLKLNTSELFEEWSKKVAEKSLSVAGSIFNVESTRTVVTVRDREPQKITVLKLKVNFLPDVITLAKEVRNMRALGFRTPLSIVNKAHSANQLYPFAISLIESVRTYESTCSKIEEHKMQNISLLTAGLRKDVQLCIHEGVQITWESYRLDQYVQKLAELVFSFQEKVDDLVIVIKEIDFNVKALETCSYNKQTFEEILIRIQEAVDNMSLHQFSNLAQWVSNLDSLVEQRLIVRLEAGLLEWIKVLKGXXXXXXXXXXXXXXXVNSMAKHRLGGKPQIKKLIHELRITNQQMHLYPSIEVATQDILYQMSSWQNIILNLSRIVHSRYQVGLETE-SDNQKTYKKLLSSLPNSGESLENAYAAVHNILRDANEYVKTWTNYQSLWDLQGDQLFSLIADDNTVWMNVLEEIKSMRKHFDVAETQKEFGPLVIAFGKVQSKVSMKYDNWHKEVLTKFGQNMGKMMTTLYNEVQRARNELEQQSIDSGGTNESVNFITYTQNIKRKMNTWEKQAEACRAGQNILCRDRFQFPNDWLDSENIQGEWSAFKEIMRRKQETISSQVASLQMKITEEDKIVESKTTEVLGNWEKDKPIAGDLTPEEAVNIIQILEGKFNRLKEERENVQKAKEALELTEIGVKPISEEKVTNALSELHDLKNVWNELKSIWEKIRDMKETPWLSVQPRKLRQDIENLTAQLKELPNSFKQYASFEHVRTLLKMYMKVNASIVELKSEAIKERHWRMLMRKLNVSWSLNELQLGKVWDIDLVKNEEIIREVLAIAQGEKALEEYLRQITEVWKNYVLELTNYQSKSKIIKGWDDLFNKVKEHINNVTSMKASPYFKQFEEEATAWEDRLNKINALFDVWIDVQRRWIYLDGIFAGSADIKVLLPVESQRFQSVSTEFLGLMKKVQKSPLVTDVLNIANVQRQLERLADLLGKIQKSLGEYLERQRSSFPRFYFVGDEDLLEIIGNSXXXXXXXXXXXXMFAGVHSIILSEDEKVILGMMSKEGEELRFISPVSIIEHPRINDWLTAMEKEMRVSLAKYLNVAVKEISGWRTESNIDKDKFMVWLDKYQAQIVVLAAQITWSEAVEASLASGV-------SLESTMTVVHSTLNMLADTVLYEQPPVRRRKLEHLIIEYVHQRDVLRALHNDGVSSNKNFDWMSQMRFYFDPKQTDPLHQLSIHVANAKFHYGFEYLGVCDRLVQTPLTDRCYLTMTQALEARLGGSPFGPAGTGKTESVKSLGNQLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLSAVSQQIQGIQEALRELMVSKKD---SINVELLGKQVHVNPDMAIFITMNPGYAGRSNLPDNLKKLFRSLAMTQPDRQLIAQVMLYSQGFRTAEVLAGKVVPFFKLCDEQLSPQSHYDFGLRALKSVLVSAGNVKRDRIKQEKEKIVARGEEINETAIAEQLPEQEILIQSVMETMVPKLIADDIPLLYSLLTDVFPGVEYRQAEMKRLREELRKVSENKFLVYSDEPNTAGYLWVEKVLQLYQITTIHHGLMMVGPSGSGKTMACRVLLQALENIDGIEGVAHIIDPKSISKDSLYGYMDPNTREWTDGLFTHILRRIIDSVRGESNKRQWIVFDGDVDPEWVENLNSVLDDNKLLTLPNGERLAIPPNVRIMFEVQDLKYATLATVSRCGMVWFSEEVLTTGMILTHFLNELKKVQVMEGEEDFSVNQGDTGADADSKISSSPIIQLQTQVSSILAPFFTEDGLIAKCLDYSTTLEHIMDFTRLRALTSLFSMIKQSIRNMIEYNQSHSDFPLNNEQIENYVAKSLISSVVWSMSGDSKLKVREQLSQYIKNISTVDLPTVGGIKNIIDFEVNIQGTWVAWSNKVPQIEVETHKITATDVVVPTMDTVRHEALLYTWLAEHRPVLLCGPPGSGKTMTLFSALRCLPDMEVVGLNFSSATTPELMLKTFDQYCEYRKTPNGIVLAPQQLNKWLIFFCDEINLPDMDKYGTQRVISFLRQMVEHHGFYRITDMQWVSFERIQFVGACNPPTDPGRKPLSHRFLRHVPVVYVDYPGETSLKQIYSTFNRAMLRMLPSLRGYADTLTNAMVEFFLKTQERFTHDMQPHYIYSPREMTRWVRGIHEALKPLESLSVEGLVRIWAHEALRLFQDRLVEEDERHWTDDNINEVALKHFPNINKEEALKRPILYSNWLSKDYSAVTQEELRDYVKARLKVFYEEELDVPLVLFNQVLDHVLRIDRVFRQPQGHLLLIGVSGAGKTTLSRFVSWINGLSVFQVKVHNKYTAEDFDEDLRNVLRRSGCKGEKITFIMDESNVMDSSFLERMNTLLANGEVPGLFEGDELTTLMTQCKEGAIREGLMIDSQEELYKWFTQQICRNLHVVFTMNPSADGLKDKASTSPALFNRCVLNWFGDWSLEAYFQVGKEFTNRLDLERTDYKVPDTLPCIAEGLLPQNPIYRDVVVNALVFVHQTMHQANVRVQKRGGRTAAITPRHYLDLIAHYMKLSAEKRADLEEQQLHLNNGLKKIEQTVDQVEVMQRSLTKKRQELENMNEAANAKLKQMVQDQQEAEQKKTTGQALKEELAKQEQFVNEKQKTVKQELDQVEPTVNEAKQAVQNIRKKDIQEIKAMKNPPNAVKMAVESICLLLGEKTTDWQSILKVIIKDTFVTSILNFNTDDVSDNTRETMKKKYLSNPDYNFEKVNKASNACGPMVKWVLAQISYADILKRVEPLRNELTELSDAAEQNRKKSQETEDLIAQLEKSIAKYTEEYATLISQAQTIKSDLASVESKVGRSVALLGSLSSERTRWDSGSETFKAQMATINGDCLLSSAFMAYGGYFDQHMRTSLFNTWCHHLSEADILFRSDLARVEYLSNPDDRLRWQANSLPADDLCVENAIILRRYNRYPLIIDPSGQATTFLLNEYKEKKITKTSFLDDSFRKTLESALRFGTPLLVQDVESYDPILNPVLNREVRRTGGRTLITLGDQDIDLSPTFTIFLSTRDPSVEFAPDICSRVTFVNFTVTRSSLQNQCLNAVLKIERPDIDQKRSDLLKAQGEFQLKLRHLEKDLLQSLNEAQGNLLENDKIIARLETLKREAADVAKKVEETDVVMQEVESVSTEYVPLAQSCSNIYFTLEAMNQIHFLYQYSLQLMLDIFSSVLINNPELTNVKAASDRLKIITKNLFQVTYNRLARGMLHEDQITFATILARIFLKGSTPIGFLENEFQHFLRSQEATITSSDSNKQDNLGLTLHQDQIDSVKRLKKLKVFAKIEEKVKSTKDIKNWTLTVTPESNVPELWVDDNNYNDEKLSKIAKGMYNLLIIQAIRPDRLLASTQKFIASVLGDTFTESVRGTLDLASIVEVEVTACVPILLCAVQGYDPSGRVEDLASEQGKQLTGIAIGSAEGFSQAEKAINSAAKTGKWVMLKNVHLATSWLVSLEKKIHSLQAHPNFRLFLTMEITPKLPVNLLRAGRVLVFEPPPGIKANLLRTLSSINNQRMSKEPVERSRLYFLLAWLNAIVQERLRYVPLGYSKKYEFGESDFKCALDTIDTWVDGAAMGRTNLPPEKIPWVALQTLLGSCIYGGKIDNAFDQRLLNSFLGYLFTEKCFDHNFALVSDADDGSNIAFPESTKHTDILQWVHKLPDLQTPSWLGLPNSAEKVLLTNLGQSLIGNILKMQQSLEDDEELVVGQS-KTKRTIEVGDGRPAWMRQLYQSTQTWLQILPKSVTPLQRTIENIKDPMYRCFEREVNSGCNLLASVRKDLEDVAEVCKGAKKPTNHHRSMMADLAKGIIPKMWIRYAIPPGLTVIQWIQDFADRIKQLLHISDTAAKSGVIALRSIQVWLGGLFMAEAYITATRQSVAQNNKWALEELFLDVELGEGK---VDSNTCVITGLRLMGSEIVDPRTLKLSTLIYKDIDICRLKWIRVEKSQQLEGSSAKDKVCLPIYLNAARSTVLFTLYF--STTDSSYDFYKRGVAI 14048 D +ANL V Q + S L K I+ L P +L +D ++ E L E E + KF++D Q+ T+ +++ T +E+ E IS V+ + + KS + FIK VI+ADK ISSQL+VL+ + P+ET+HS + + P+FKSYI++ GK M PSVEKKIAELE+GLLHLQQNIEIPEI+L HP + ++ ++ + ++ +V+DF DK ED FLNQLQ+GVNRWI+EIQKVTKL+RDP++GTALQEISFWLNLE +L +IQEKRES EV LTL ILK KRFHAT SFDTDT L A V DYN LMKDFP+NDLLSA++LDKI +AL IF+HL+K+R TKYP+ R ++L+EA+SRDL++QL+KV+ LM + Y+EFEK+ AC +VF TW+DEY+K+Q LLRDI K+KREE K W++N H+KLQ RL+ ++KFR QHEQLR VIVRVL+P VT V + VP+ Q K + L ++AD ++I+EVN AYE VK +D LD +KE + W+AA+KRY+ERIDRVE+RI + LRD LG +KNANEMFR FSRFNALFVRPHIRGAI EYQTQLIQRVKDDIE+LH+KFKVQY S ACKMS VRDLPPVSGSIIW +QI RQL AYMKRVEDVLGK W H+EGQKLK DG+SF++KLNT E+F++W++KV +++L V+G IF +ESTR R R VLKLKVNFLP++ITL+KEVRN++ LGFR PL+IVNKAH ANQLYPFAISLIESVRTYE TC K+EE +ISLL AGL+K+VQ I EG+ + WESY+LD YVQ+LAE VF+FQEKVDDL+I+ ++ID V++LETC Y+ +TF EIL R+Q+AVD+++LH +SNL WV+ LD +E+ L RL+AGL W VL G++ + + D DTD H+ GG+P+IK ++HELRITNQ ++L P IE + +M SW+ +IL+L RI RYQVG+ E S+ +K Y+ L+ +P+ SLE AY+AV I+ + +YVK W YQ LWD+Q + +++ + +D W +L +I+ R FD AET+KEFGP++I +GKVQSKV++KYD+WHKEVL+KFGQ +G+ MT ++++ ++R ELEQ S+D+ T+++V FITY Q++KRK+ +EKQ + R GQ +L + RFQFP+ WL +NI+GEW AF +IMRRK I QVA+LQMKI +ED+ VES+T ++L +WEK KP+AG+L PEEA+ + I EGKF RLK++RE KAKEALELT+ G+ SEE+V AL EL DLK VW+EL +WE+I MKE PW+SVQPRKLRQ+++ L QLK P +QYAS+E+V+ LLK YMKVN ++ELKSEA+K+RHW+ LM++L+V+W ++EL LG++WD+DL +NE I+++VL +AQGE ALEE+L+QI EVW Y L+L NYQ+K ++I+GWDDLFNKVKEHIN+V++MK SPY+K FEE+A +WED+LN+I ALFDVWIDVQRRW+YL+GIF GSADIK LLPVE+QRFQS+STEFL LMKKV KSPLV DVLNI VQR LERLADLLGKIQK+LGEYLER+RSSFPRFYFVGDEDLLEIIGNSK++ KLQKHFKKMFAGV SIIL+ED V+LG+ S+EGEE+ F +PVSI EHP+IN+WLT +EKEMRV+LAK L +V E+ + ++ID ++ W+DKYQAQ+VVL+AQI WSE VE++L+S L+S T V +TLN+LAD+VL EQPP+RRRKLEHLI E VHQRDV R L + S K+F+W+SQMRFYFDPKQTD L QLSI +ANAKF+YGFEYLGV D+LVQTPLTDRCYLTMTQALEARLGGSPFGPAGTGKTESVK+LG+QLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLSAVSQQ+Q IQEALRE +D +I ELL KQV V+PDMAIFITMNPGYAGRSNLPDNLKKLFRSLAMT+PDRQLIAQVMLYSQGFRTAEVLA K+VPFFKLCDEQLS QSHYDFGLRALKSVLVSAGNVKR+RI++ K++ RGE ++E +AE LPEQEILIQSV ETMVPKL+A+DIPLL+SLL+DVFPGV+Y + EM LREEL+KV + +L Y D G +WVEKVLQLYQIT I+HGLMMVGPSGSGK+MA RVLL+ALE ++G+EGVAHIIDPK+ISKD LYG +DPNTREWTDGLFTH+LR+IID+VRGE KRQWI+FDGDVDPEWVENLNSVLDDNKLLTLPNGERL++PPNVRIMFEVQDLKYATLATVSRCGMVWFSE+VL+T MI +FL ++ + + EGE++ + G + + + SSSP++Q+Q +++L P+FT +GL+ K L+++ LEHIMD TRLR L SLFSM+ Q+ RN+ +YN +H DFP+ +Q+E Y+ + LI +++WS SGD +LK+R +L +YI+ I+TV LP+ I IID+EV+I G W W KVPQIEVETHK+ A DVVVPT+DTVRHEALLYTWLAEH+P++LCGPPGSGKTMTLFSALR LPDMEVVGLNFSSATTPEL+LKTFD YCEYR+TPNG+VLAP QL KWL+ FCDEINLPDMDKYGTQRVISF+RQMVEH GFYR +D WV ERIQFVGACNPPTDPGRKPLSHRFLRHVPVVYVDYPG SL QIY TFNRAMLR++PSLR YA+ LT AMVEF+ +QERFT D+QPHYIYSPREMTRWVRGI EAL+PLE+L VEGL+RIWAHEALRLFQDRLVE++ER WTD+NI+ VALKHFPN+ K++AL RPILYSNWLSKDY V QEELRDYVKARLKVFYEEELDVPLVLFN+VLDHVLRIDR+FRQPQGHLLLIGVSGAGKTTLSRFV+W+NGLSV+Q+KVH KYT EDFDEDLR VLRRSGCK EKI FIMDESNV+DS FLERMNTLLANGEVPGLFEGDE TLMTQCKEGA +EGLM+DS EELYKWFT Q+ RNLHVVFTMNPS++GLKD+A+TSPALFNRCVLNWFGDWS EA +QVGKEFT+++DLE+ +Y VPD +P + + LPQ P +R+ +VN VFVHQT+HQAN R+ KRGGRT AITPRHYLD I HY L EKR++LEEQQ+HLN GL+KI++TVDQVE ++R L K QELE N A K +M++D K Q ++E+L KQ+ + +KQ +VK++LDQVEP V EA+ AV++I+K+ + E+++M NPP AVK+A+ESICLLLGE TTDW+ I +I+++ F+ +I+NF+ +++SD RE MKK YLSNP +N+E VN+AS ACGPMVKW +AQ++YAD+LKRVEPLRNEL +L D A+ N++K+ E E +I LE SIA+Y EEYA LIS+AQ IK+DLA+VE+KV RS ALL SLS+ER RW+ SETFK QM+TI GDCLLS+AF+AY GYFDQ MR +LF TW HHL +A++ FR+D+AR EYLSN D+RLRWQANSLPADDLC ENAI+L+R+NRYPLIIDPSGQAT F++NEYK++KIT+TSFLDD+FRK LESALRFG PLLVQDVESYDPILNPVLNREVRRTGGR LITLGDQDIDLSP+F IFLSTRDP+VEF PD+CSRVTFVNFTVTRSSLQ+QCLN VLK ERPD+D+KRSDLLK QGEFQL+LR LEK LLQ+LNE +G +L++D II LE LK+EAA+V +KVEETD+VMQEVESVS +Y+PL+ +CS+IYFT+E++ QIHFLYQYSLQ LDI+ +VL N L + RL +ITK+LFQV +NR+ARGMLH+D ITFA +LARI LKG+ + EFQHFLR ++ + S+ K GLT ++Q++++ RL L F + KV++ + W + +PE VP +W + D+ + I + ++ LL+IQA RPDRLLA F+++VLGD+F + +DLA IV+ EV P+L+C+V GYD SGRVEDLA+EQ Q+T IAIGSAEGF+QAEKAIN+A K+G+WVMLKNVHLA WL+ LEKK+HSLQ H FRLFLTMEI PK+PVNLLRAGR+ VFEPPPG+KAN+LRT SSI R+ K P ER+RLYFLLAW +AI+QERLRY PLG+SKKYEFGESD + A DT+DTW+D A GR N+ P+KIPW AL+TL+ IYGG+IDN FDQRLLN+FL LFT FD F L D +I P+ + + +QWV LPD QTPSWLGLPN+AE+VLLT G +IG +LKMQ LED+++L ++ K +RT DGRPAWMR L+ + WLQ++P+++ L+RT+ENIKDP++R FEREV G LL VR+DL DV +VC+G KK TN+ R+++ +L KGI+P W R+ +P GLTVIQW+ DF++R+KQL +IS AA G L+++ VW+GGLF+ EAYITATRQ VAQ N W+LEEL L+V + + +D+ + +TGL+L G+ + + L LS I + I +L+W ++Q + V LP+YLN R+ ++FT+ F +T + + FY+RGVAI Sbjct: 9 DSSANLEVSAAVQNVADTSVLQKHIRKLV----PLLL-EDGGETPASLESALEEKSALEQMRKFLSDPQIHTILVERSTLKEDVGDEGEEEKEFISYNVSIDIHYGMKSNSLAFIKRTLVIDADKPISSQLRVLTLSEDSPYETLHSFISNAVGPFFKSYIRESGKADRDGDK-MAPSVEKKIAELEMGLLHLQQNIEIPEISLLIHPNITNVAKQCYERGEKPKVTDFGDKVEDPTFLNQLQSGVNRWIREIQKVTKLDRDPASGTALQEISFWLNLERALYRIQEKRESPEVLLTLDILKHGKRFHATVSFDTDTGLKQALETVNDYNPLMKDFPLNDLLSATELDKIRQALVAIFTHLRKIRNTKYPIQRALRLVEAISRDLSSQLLKVLGTRKLMHVAYEEFEKVMVACFEVFQTWDDEYEKLQVLLRDIVKRKREENLKMVWRINPAHRKLQARLDQMRKFRRQHEQLRAVIVRVLRPQVTAVAQQNQGEVPEPQDM----KVAEVLFDAADANAIEEVNLAYENVKEVDGLDVSKEGTEAWEAALKRYDERIDRVETRITARLRDQLGTAKNANEMFRIFSRFNALFVRPHIRGAIREYQTQLIQRVKDDIESLHDKFKVQYPQSQACKMSHVRDLPPVSGSIIWAKQIDRQLTAYMKRVEDVLGKGWENHVEGQKLKQDGDSFRMKLNTQEIFDDWARKVQQRNLGVSGRIFTIESTRA----RGRTG---NVLKLKVNFLPEIITLSKEVRNLKWLGFRVPLAIVNKAHQANQLYPFAISLIESVRTYERTCEKVEERN--SISLLVAGLKKEVQALIAEGIALVWESYKLDPYVQRLAETVFNFQEKVDDLLIIEEKIDLEVRSLETCMYDHKTFSEILNRVQKAVDDLNLHSYSNLPIWVNKLDMEIERILGGRLQAGLKTWTLVLMGQSDDKADVDMDTDA---PQVSHKPGGEPKIKNVVHELRITNQVIYLNPPIEDCRYKLYQEMFSWKMVILSLPRIQSQRYQVGVHYELSEEEKYYRNALTRMPDGPASLEEAYSAVMGIVTEVEQYVKVWLQYQCLWDMQAENIYNRLGEDLNKWQALLVQIRKARGTFDNAETRKEFGPVIIDYGKVQSKVNLKYDSWHKEVLSKFGQMLGQNMTEFHSQISKSRQELEQHSVDTASTSDAVTFITYVQSLKRKIKQFEKQVDLYRNGQRLLEKQRFQFPSSWLYIDNIEGEWGAFNDIMRRKDSAIQQQVANLQMKIVQEDRAVESRTIDLLTDWEKTKPVAGNLRPEEALQALTIYEGKFGRLKDDREKCAKAKEALELTDTGLLSGSEERVQVALEELQDLKGVWSELSKVWEQIDQMKEQPWVSVQPRKLRQNLDGLLNQLKNFPARLRQYASYEYVQRLLKGYMKVNMLVIELKSEALKDRHWKQLMKRLHVNWVVSELTLGQIWDVDLQRNEAIVKDVLLVAQGEMALEEFLKQIREVWNAYELDLVNYQNKCRLIRGWDDLFNKVKEHINSVSAMKLSPYYKVFEEDALSWEDKLNRIMALFDVWIDVQRRWVYLEGIFTGSADIKHLLPVETQRFQSISTEFLALMKKVTKSPLVMDVLNIQGVQRSLERLADLLGKIQKALGEYLERERSSFPRFYFVGDEDLLEIIGNSKNVAKLQKHFKKMFAGVSSIILNEDSSVVLGISSREGEEVIFKTPVSITEHPKINEWLTLVEKEMRVTLAKLLAESVTEVEIFGKSTSIDPATYITWIDKYQAQLVVLSAQIAWSENVESALSSAAVGGGDSSPLQSVQTNVEATLNVLADSVLMEQPPLRRRKLEHLITELVHQRDVTRTLMKIKIDS-KSFEWLSQMRFYFDPKQTDVLQQLSIQMANAKFNYGFEYLGVQDKLVQTPLTDRCYLTMTQALEARLGGSPFGPAGTGKTESVKALGHQLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLSAVSQQVQCIQEALREHSNPNRDKTHTITCELLNKQVKVSPDMAIFITMNPGYAGRSNLPDNLKKLFRSLAMTKPDRQLIAQVMLYSQGFRTAEVLANKIVPFFKLCDEQLSSQSHYDFGLRALKSVLVSAGNVKRERIQKIKKEKQERGEVVDEGEVAENLPEQEILIQSVCETMVPKLVAEDIPLLFSLLSDVFPGVQYHRGEMTALREELKKVCQEMYLTYGDGEEVGG-MWVEKVLQLYQITQINHGLMMVGPSGSGKSMAWRVLLKALERLEGVEGVAHIIDPKAISKDHLYGTLDPNTREWTDGLFTHVLRKIIDNVRGELQKRQWIIFDGDVDPEWVENLNSVLDDNKLLTLPNGERLSLPPNVRIMFEVQDLKYATLATVSRCGMVWFSEDVLSTDMIFNNFLARMRSIPLDEGEDE--AQRRRKGIEDEGEESSSPMLQIQRDAATVLQPYFTSNGLVIKALEHAFKLEHIMDLTRLRCLGSLFSMLHQACRNIAQYNANHPDFPMQIDQLERYIQRYLIYAILWSFSGDGRLKMRAELGEYIRRITTVPLPSAPNIP-IIDYEVSITGEWQPWQCKVPQIEVETHKVAAPDVVVPTLDTVRHEALLYTWLAEHKPLVLCGPPGSGKTMTLFSALRALPDMEVVGLNFSSATTPELLLKTFDHYCEYRRTPNGVVLAPVQLGKWLVLFCDEINLPDMDKYGTQRVISFIRQMVEHGGFYRTSDQTWVKLERIQFVGACNPPTDPGRKPLSHRFLRHVPVVYVDYPGPASLTQIYGTFNRAMLRLIPSLRTYAEPLTAAMVEFYTMSQERFTQDIQPHYIYSPREMTRWVRGIFEALRPLETLPVEGLIRIWAHEALRLFQDRLVEDEERRWTDENIDTVALKHFPNVEKDKALNRPILYSNWLSKDYIPVDQEELRDYVKARLKVFYEEELDVPLVLFNEVLDHVLRIDRIFRQPQGHLLLIGVSGAGKTTLSRFVAWMNGLSVYQIKVHRKYTGEDFDEDLRTVLRRSGCKNEKIAFIMDESNVLDSGFLERMNTLLANGEVPGLFEGDEYATLMTQCKEGAQKEGLMLDSHEELYKWFTSQVIRNLHVVFTMNPSSEGLKDRAATSPALFNRCVLNWFGDWSTEALYQVGKEFTSKMDLEKPNYIVPDYMPVVYDK-LPQPPSHREAIVNGCVFVHQTLHQANARLAKRGGRTMAITPRHYLDFINHYADLFNEKRSELEEQQMHLNVGLRKIKETVDQVEELRRDLRIKSQELEVKNAAEKTKTHKMLKD-------KVMSQEIQEQLHKQQAIIADKQMSVKEDLDQVEPAVIEAQNAVKSIKKQHLVEVRSMANPPAAVKLALESICLLLGESTTDWKQIRSIIMRENFIPTIVNFSAEEISDAIREKMKKNYLSNPSFNYELVNRASLACGPMVKWAIAQLNYADMLKRVEPLRNELQKLEDDAKDNQQKANEVEQMIRDLEASIARYKEEYAVLISEAQAIKADLAAVEAKVNRSTALLKSLSAERDRWEKTSETFKNQMSTIAGDCLLSAAFIAYAGYFDQQMRQNLFTTWSHHLQQANVQFRTDIARTEYLSNADERLRWQANSLPADDLCTENAIMLKRFNRYPLIIDPSGQATEFIMNEYKDRKITRTSFLDDAFRKNLESALRFGNPLLVQDVESYDPILNPVLNREVRRTGGRVLITLGDQDIDLSPSFVIFLSTRDPTVEFPPDLCSRVTFVNFTVTRSSLQSQCLNEVLKAERPDVDEKRSDLLKLQGEFQLRLRQLEKSLLQALNEVKGRILDDDTIITTLENLKKEAAEVTRKVEETDIVMQEVESVSHQYLPLSTACSSIYFTMESLKQIHFLYQYSLQFFLDIYHTVLYENANLKGTIDHTQRLSVITKDLFQVAFNRVARGMLHQDHITFAMLLARIKLKGTIGEPAYDLEFQHFLRGKQIVLGSTFVPKIS--GLT--EEQVEAMMRLSNLSAFKDVISKVEADEQFCIWLDSSSPEQTVPYIWSE-----DKPATPIGQAVHRLLLIQAFRPDRLLAMAHIFVSTVLGDSFMSIIDQPIDLAHIVDTEVKPNTPVLMCSVPGYDASGRVEDLAAEQNTQITSIAIGSAEGFNQAEKAINTAVKSGRWVMLKNVHLAPGWLMQLEKKLHSLQPHACFRLFLTMEINPKVPVNLLRAGRIFVFEPPPGVKANMLRTFSSIPVSRICKSPNERARLYFLLAWFHAIIQERLRYAPLGWSKKYEFGESDLRSACDTVDTWLDDTAKGRQNISPDKIPWSALKTLMAQSIYGGRIDNEFDQRLLNTFLERLFTTSSFDSEFKLACKVDGHKDIQMPDGIRRDEFVQWVETLPDTQTPSWLGLPNNAERVLLTTQGIDMIGKMLKMQM-LEDEDDLAYAETEKKQRTDSTSDGRPAWMRTLHITACNWLQVIPQALNHLKRTVENIKDPLFRFFEREVKMGAKLLHDVRQDLTDVVQVCEGKKKQTNYLRTLINELVKGILPHSWSRFTVPAGLTVIQWVADFSERVKQLQNISQAAANGGAKELKNLHVWIGGLFVPEAYITATRQYVAQANSWSLEELCLEVSVTTVQNTVLDAYSFGVTGLKLQGATCTNNK-LSLSNAISTVLPITQLRW-----TKQTHTEKKANVVTLPVYLNFTRADLIFTVDFEIATKEDPHSFYERGVAI 4633
BLAST of Cytoplasmic dynein 1 heavy chain 1 vs. Ensembl Xenopus
Match: DNAH10 (dynein axonemal heavy chain 10 [Source:NCBI gene;Acc:100492440]) HSP 1 Score: 1380.93 bits (3573), Expect = 0.000e+0 Identity = 959/3374 (28.42%), Postives = 1702/3374 (50.44%), Query Frame = 3 Query: 3927 EEAVNIIQILEGKFNRLKEERENVQKAKEALELTEIGVKP--ISEEKVTNALSELHDLKNVWNELKSIWEKIRDMKETPWLSVQPRKLRQDIENLTAQLKELPNSFKQYASFEHVRTLLKMYMKVNASIVELKSEAIKERHWRMLMRKLNVSWSLNE--LQLGKVWDIDLVKNEEIIREVLAIAQGEKALEEYLRQITEVWKNYVLELTNY----QSKSKIIKGWDDLFNKVKEHINNVTSMKASPYFKQFEEEATAWEDRLNKINALFDVWIDVQRRWIYLDGIFAGSADIKVLLPVESQRFQSVSTEFLGLMKKVQKSPLVTDVLNIANVQRQLERLADLLGKIQKSLGEYLERQRSSFPRFYFVGDEDLLEIIGNSXXXXXXXXXXXXMFAGVHSIILSED---EKVILGMMSKEGEELRFISPVSIIEHPRINDWLTAMEKEMRVSLAKYLNVAVKEISGWR---TESNIDKDKFMVWLDKYQAQIVVLAAQITWSEAVEASL-----ASGVSLESTMTVVHSTLNMLADTVLYEQPPVRRRKLEHLIIEYVHQRDVLRALHNDGVSSNKNFDWMSQMRFYFDPKQTDPLHQLSIHVANAKFHYGFEYLGVCDRLVQTPLTDRCYLTMTQALEARLGGSPFGPAGTGKTESVKSLGNQLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLSAVSQQIQGIQEALRELMVSKKDSINVELLGKQVHVNPDMAIFITMNPGYAGRSNLPDNLKKLFRSLAMTQPDRQLIAQVMLYSQGFRTAEVLAGKVVPFFKLCDEQLSPQSHYDFGLRALKSVLVSAGNVKRDRIKQEKEKIVARGEEINETAIAEQLPEQEILIQSVMETMVPKLIADDIPLLYSLLTDVFPGVEYRQAEMKRLREELRK-VSENKFLVYSDEPNTAGYLWVEKVLQLYQITTIHHGLMMVGPSGSGKTMACRVLLQALENIDGIEGVAHIIDPKSISKDSLYGYMDPNTREWTDGLFTHILRRIIDSVRGESNKRQWIVFDGDVDPEWVENLNSVLDDNKLLTLPNGERLAIPPNVRIMFEVQDLKYATLATVSRCGMVWFSEEVLTTGMILTHFLNELKKVQVMEGEEDFSVNQGDTGADADSKISSSPIIQLQTQVSSILAPFFTEDGLIAKCLDYSTTLEHIMDFTRLRALTSLFSMIKQSIRNMIEYNQSHSDFPLNNEQIENYVAKS-LISSVVWSMSGDSKLKVREQLSQYIKNISTV----DLPTVGGI-------KNIIDFEVNIQGT-WVAWSNKVPQIEVETHKITATDVVVPTMDTVRHEALLYTWLAEHRPVLLCGPPGSGKTMTLFSALRCLPDMEVVGLNFSSATTPELMLKTFDQYCEYRKTPNGIVLAPQQLNKWLIFFCDEINLPDMDKYGTQRVISFLRQMVEHHGFY-RITDMQWVSFERIQFVGACNPPTDPGRKPLSHRFLRHVPVVYVDYPGETSLKQIYSTFNRAMLRML-PSLRGYADTLTNAMVEFFLKTQERFTHDMQP-----HYIYSPREMTRWVRGIHEALKPLESLSVEGLVRIWAHEALRLFQDRLVEEDERHWTDDNINEVALKHFPNINKEEALKRPILYSNWLS--KDYSAVTQEELRDYVKAR------LKVFYEEELDVPLVLFNQVLDHVLRIDRVFRQPQGHLLLIGVSGAGKTTLSRFVSWINGLSVFQVKVHNKYTAEDFDEDLRNVLRRSGCKGEKITFIMDESNVMDSSFLERMNTLLANGEVPGLFEGDELTTLMTQCKEGAIREGLMIDSQEELYKWFTQQICRNLHVVFTMNPSADGLKDKASTSPALFNRCVLNWFGDWSLEAYFQVGKEFTNRLDLERTDYKVPDTLPCIAEGLLPQNPIYRDVVVNALVFVHQTMHQANVRVQKRGGRTAAITPRHYLDLIAHYMKLSAEKRADLEEQQLHLNNGLKKIEQTVDQVEVMQRSLTKKRQELENMNEAANAKLKQMVQDQQEAEQKKTTGQALKEELAKQEQFVNEKQKTVKQELDQVEPTVNEAKQAVQNIRKKDIQEIKAMKNPPNAVKMAVESICLLLGEKTTDWQSILKVIIKDTFVTSILNFNTDDVSDNTRETMKKKYLSNPDYNFEKVNKASNACGPMVKWVLAQISYADILKRVEPLRNELTELSDAAEQNRKKSQETEDLIAQLEKSIAKYTEEYATLISQAQTIKSDLASVESKVGRSVALLGSLSSERTRWDSGSETFKAQMATINGDCLLSSAFMAYGGYFDQHMRTSL-FNTWCHHLSEADILFR----SDLARVEYLSNPDDRL-RWQANSLPADDLCVENAIILRRYNRYPLIIDPSGQATTFLLNEYKEKKITKTSFLDDSFRKTLESALRFGTPLLVQDVESY-DPILNPVLNREVRRTGGRTLITLGDQDIDLSPTFTIFLSTRDPSVEFAPDICSRVTFVNFTVTRSSLQNQCLNAVLKIERPDIDQKRSDLLKAQGEFQLKLRHLEKDLLQSLNEAQGNLLENDKIIARLETLKREAADVAKKVEETDVVMQEVESVSTEYVPLAQSCSNIYFTLEAMNQIHFLYQYSLQLMLDIFSSVLINN-PELTNVKAASDRLKIITKNLFQVTYNRLARGMLHEDQITFA-TILARIF-LKGSTPIGFLENEFQHFLRSQEATITSSDSNKQDNLGLTLHQDQIDSVKRLKKL--KVFAKIEEKV-KSTKDIKNWTLTVTPESNVPELWVDDNNYNDEKLSKIAKGMYNLLIIQAIRPDRLLASTQKFIASVLGDTFTESVRGTLDLASIVEVEVTACVPILLCAVQGYDPSGRVEDLASEQ---GKQLTGIAIGSAEGFSQAEKAINSAAKTGKWVMLKNVHLATSWLVSLEKKIHSL-QAHPNFRLFLTMEITPKLPVNLLRAGRVLVFEPPPGIKANLLRTLSSINNQRM-SKEPVERSRLYFLLAWLNAIVQERLRYVPLGYSKKYEFGESDFKCALDTIDTWVDGAAMGRTNLPPEKIPWVALQTLLGSCIYGGKIDNAFDQRLLNSFLGYLFTEKCFDHNFALVSDADDGSNIAFPESTKHTDILQWVHKLPDLQTPSWLGLPNSAEKVLLTNLGQSLIGNILKMQQSLEDDEELVVGQSKTKRTIEVGDGRPAWMRQLYQSTQT----WLQILPKSVTPLQRTIENIKDPMYRCFEREVNSGCNLLASVRKDLEDVAEVCKGAKKPTNHHRSMMADLAKGIIPKMWIRYAIPPGLTVIQWIQDFADRIKQLLHISDTAAKSGVIALRSIQVWLGGLFMAEAYITATRQSVAQNNKWALEELFLDVELGEGKVDSNT-------CVITGLRLMGSE 13817 ++ + ++ E + + +++R+ + A++ +L I + P I +K L +++++ N + K W +T W ++ + L I+ ++L + ++ + +K + + +++LK+EA+++RHW+ LM K + +N L ++ ++L K + I +++A A E ++E+ +++I + W+N + Y Q + I+ D++ + ++ N+ S+ S + F WE L+ I + +VW+ VQR+W+YL+ IF G DI+ LP E+++F ++ F +M + K P++ +N L+ L++ L + QKSL +YL+ +R++FPRF+F+ D++LL I+G+S + K M+ + S+ E E M+S EGE + F V+ R+ DW+T + +EMR + N + + + +R +S +D W+ YQ +V+ Q+ W+ VE +L++ +H ++ L + R+K ++I VH RD++ D + + F+W SQ+RFY+D ++ D +L++ F YG+EY+G+ RLV TPLTDR YLT+TQAL LGG+P GPAGTGKTE+ K L LG +V NC E D++A+G+IF GL Q GAWGCFDEFNR++ +LS +S QIQ I+ AL + + G+++ ++ M IFITMNPGYAGR+ LP+++K LFR + + PD Q I ++ML+S+GF A+ LA K+ +KL EQLS Q HYDFGLRALKSVLV AG +KR + L E +L++++ + +PK + +D+PL L++D+FPG++ + + + + + EN +++ + V+KV+Q+Y+ H M+VGP+G GK++ L A + G+ + ++PK++S LYG +DP TR+WTDG+ ++I R I E +R++I+FDGDVD WVEN+NSV+DDNKLLTL NGER+ + P+ ++FEV DL+YA+ ATVSRCGMV+ + L ++N + SK Q S+L+ F + + C++ +E I D + L ++ + Q+ NM+ + D L E + V + I ++ WS+ R + +YIK ++++ D + G I DF + + W+ WS VP+ + + D++VPT+DT R LL + RPV+L G G+ KT T + LR L ++ +NFSS TT + + + E R N P + K L+ F D++N+P +D+YGTQ+ I+ L+ ++E G Y R ++ + F+ A GR + RF+ V V +P E SL IYS+ + + ++ D LT +E + + D+ P HYI++ R+++R G+ P +V +VR+W +E LR+F DRLV E+++ +I + +HF + E A + PIL+ ++ + + E+++DY A+ L+ + E + + LVLF+ L+H+ RI R+ R +GH LL+GV G+GK +L+R ++ G VF++ + Y F EDLRN+ + G + +K+ F+ +++V + FLE +N +L +G VP LF DE ++++Q ++ A + G+ ++E ++++F + NLH+V M+P D L+ + P L N ++WF W +A + V F L + + P V +V VH ++ + + + Q++ R+ +TP++YLD I Y +L EK Q L GL K+++ Q+ + L +++ L + A A L ++ + AE+K+ + E+ +Q + + +++ + L + P + AK +Q + K D+ EI++ PP AV++ E I ++ G K W+S ++ +F+ S++ + D ++ + + ++ +L + FE++ S A M+K+V A + Y D+ K ++P R ++ +L +++ ++ + ++ ++ + E+Y I++ Q ++ + +E ++ + L+ L SE RW + E K + + GDCLL SAF++Y G F+ R + + W + DIL R S R+E L D + RW + LP D+L ++N I+ R +R+PL IDP QA ++ + ++ + +SF D F K LE A+++G P L QDV+ Y DP+++ VL + ++ GR I LGD+++D P F ++L+T+ + +++P + + +N+TVT L++Q L+ ++ ER +++++R +L++ E + L+ LE LL+ L + GN+L+N +++ LE K +A +V++K++ + +++ + Y P A+ + ++F L M ++ +YQYSL L +F L + P+ +K RLK I L YN G+ + ++ F+ + +I G P + E FL+ I+ S ++ Q D + RL +L +F + V + + K W T E L YND KLS K LL+++ R DR+ + ++ +G+ + + + +I E V PI+ G DP+ + LA G +L +A+G + A + + +A G+W+ML+N HL WL LEK + + + HP+FRL+LT + T + P+ +L+ +V EPP G+K N+ T I+++ + S + L ++LA+ +A+VQER ++ +G++ Y+F ESDF+ ++ ++T++ A KIPW +L+ L+G +YGG+ ++FD+R+L +++ + FD ++ + PE T ++ + LP TP GL ++AE T + + ++L++Q E G S+ + +V + Q++ Q L+I P +V LQ E+ L+ + + L ++ G ++ + L G IP +W R A ++ W+ F R Q + + + +WL GL + E+Y+TA Q+ + N W L+ L ++ + C I+GL L G++ Sbjct: 1284 DKGLQVLSAFEKELAKYEKDRQELANAEKLFDLP-ITMYPELIQIQKEMKGLQQIYEIYNAQKQAKEEW------SQTLWANLNVQILLDGIDGFLKAFRKLSKDIRSLPVAFYLESKMKEFKESIPLLLDLKNEALRDRHWKELMTKTGTDFEMNPETFTLENMFAMELHKYADAISDIVASAVKELSIEKGVKEILDTWENMKFTVQRYIKGTQDRGSILGTVDEILQILDDNAMNLQSISGSRFVGPFLNTVQQWEKTLSLIGEVIEVWMVVQRKWMYLESIFIG-GDIRSQLPDEAKKFDNIDRIFKRIMSETVKDPVIKRCCQASNRLSDLQNLSEGLERCQKSLNDYLDSKRNAFPRFFFISDDELLSILGSSDPTCVQEHIIK-MYDNIASLKFQEGDNGEMKATAMVSAEGEVMPFRQVVA--AEGRVEDWMTTVLQEMRRT-----NRLITKEAIFRYCEDKSRVD------WMLLYQGMVVLAGNQVWWTWEVEDVFRKVKKGEKQALKNYAKKMHQQIDELVTRITKPLSKNDRKKYNTVLIIDVHARDIVDIFVRDSIMDAREFEWESQLRFYWD-REPD---ELNVRQCTGTFAYGYEYMGLNGRLVITPLTDRIYLTLTQALSMYLGGAPAGPAGTGKTETTKDLAKALGLLCVVTNCGEGMDYKAVGKIFSGLAQCGAWGCFDEFNRIDASVLSVISSQIQTIRNALIHHLK------RFQFEGQEIALDARMGIFITMNPGYAGRTELPESVKALFRPVVVIVPDLQQICEIMLFSEGFLQAKNLAKKMTVLYKLAREQLSKQHHYDFGLRALKSVLVMAGELKRG---------------------SPDLNEDVVLMRALRDMNLPKFVFEDVPLFLGLISDLFPGLDCPRVRYPDFNDAVEEALQENNYILLPTQ--------VDKVVQMYETMLTRHTTMVVGPTGGGKSVVINTLCLAQTKL-GLVTKLYTLNPKAMSVIELYGILDPATRDWTDGVLSNIFREINKPT--EKKERRYILFDGDVDALWVENMNSVMDDNKLLTLANGERIRLQPHCALLFEVGDLQYASPATVSRCGMVFVDPKNLKYMPYWQKWVN-----------------------NRQSK-----------QEQSVLSKLF--EKYVPHCIE--MIVEGITDGKQGEKLKTI---VPQTDLNMVTQLSTMLDALLEKEVDDADVLECYFIEAMYWSLGATLLETGRIKFDEYIKRLASMSAAYDESILAGPGELPYQQPTIYDFHFDGEKKKWIPWSKLVPKY-IHKPEEKFIDILVPTVDTTRTTWLLEQMVKIKRPVVLVGESGTSKTATTLNLLRNLNTDMLLSINFSSRTTSMDIQRNLEANVEKRTKDN---YGPP-MGKRLLVFMDDMNMPKVDEYGTQQPIALLKLLLEKGGMYDRGKELNCKYLRDLGFIAAMGK-AGGGRNEVDTRFISLFSVFNVLFPSEESLSLIYSSILKGHTALFNEEVQAICDKLTFCTLELY----KMIVRDLPPTPSKFHYIFNLRDLSRVYNGL-VLTTPERFQTVAQMVRVWRNENLRVFHDRLVNEEDK-LVQGHIKHLIEEHF-QASLEHATRDPILFGDYRTAMSEGEPRVYEDIQDYEAAKALFQEILEEYNESKTKMNLVLFDDALEHLTRIHRIIRMDRGHALLVGVGGSGKQSLARLAAYAAGYEVFEIVLSRGYGENSFREDLRNLYIKLGLENKKMIFLFTDAHVAEEGFLELINNMLTSGMVPALFPDDEKESVLSQIRDEATKHGVG-PAKESIWQFFVNKSANNLHIVLGMSPVGDTLRTRCRNFPGLVNNTGIDWFLPWPPQALYAVANSFLGDNSLIPSQHSEP--------------------VTGHVVMVHDSVGKFSKKFQQKLRRSNYVTPKNYLDFINTYSRLLEEKNQYNLAQCKRLEGGLDKLKEATVQLAELNVKLAEQKVVLAEKSSACEALLDEISTNTTIAEEKRKLAEEKAAEIEEQNKVIAVEKQEAESALAEALPILEAAKLELQKLDKSDVTEIRSFAKPPRAVQVVCECILVMRGYKEISWKSAKGMMSDPSFLKSLMEIDFDAITQHQVKAVRG-FLKTLNTTFEEMEAISKAGLGMLKFVEAVMGYCDVAKEIKPKREKVAKLERNYYMSKRDLEKIQAELSTIQNELKALGEKYEAAITEKQKLQEEAEVMERRLIAADKLISGLGSENKRWTNDLEELKVRRVKLLGDCLLCSAFLSYEGAFNWDFRKEMVYTEW-----QQDILAREIPLSQPFRIESLLTDDVEISRWGSEGLPPDELSIQNGILTTRASRFPLCIDPQQQALNWIKRKEEKNNLKISSFNDPDFLKQLEMAIKYGFPFLFQDVDEYIDPVIDNVLEKNIKGAQGRQFIILGDKEVDYDPNFKLYLNTKLSNPKYSPSVFGKAMVINYTVTLKGLEDQLLSVIVGFERRELEEQRENLIQETSENKKLLKDLEDSLLRELATSTGNMLDNVELVHTLEETKAKATEVSEKLKLAEKTAVDIDKLRDGYRPAAKRGAILFFVLSEMALVNSMYQYSLSSFLAVFDHSLRKSLPDGILMK----RLKNIMDTLTYNVYNYGCTGLFEKHKLLFSFNMTVKIEQADGRVP----QEELDFFLK---GNISLEKSKRKKPCSWIPDQGWEDII-RLSELFPSMFGSLPSDVERCEAEWKAWYDLDTLEQYPYPL-----GYND-KLSDFQK----LLLLRCFRVDRVYRAVSDYVTVTMGEKYVQP--PVISFEAIFEQSVPTS-PIVFILSPGSDPASDLMKLAERSGFGGNRLKFLAMGQGQE-KVALQLLETAVFRGQWLMLQNCHLLVKWLKDLEKALEMIKKPHPDFRLWLTTDPTKEFPIGILQKSLKVVTEPPNGLKLNMRATYFKISHEALDSCQHSAFKSLVYVLAFFHAVVQERRKFGKIGWNVPYDFNESDFQVCMEILNTYLTKAFQQHDT----KIPWGSLKYLIGEVMYGGRAIDSFDRRILTTYMDEYLGDFIFDTFQLFHFYKNEEVDYRIPEGTTKDAFVEAIESLPLANTPEVFGLHSNAEIGYYTQAARDMWTHLLELQPQ---TGESSTGISRDEYIGQVAKDIENKLPQIFDLDQIRKNLGLEISPTTVVLLQ----------------ELERFNKLIIRMSRSLVELQRALAGEVGMSSELDEVARALFNGQIPNIWRRLAPDTLKSLGNWMIHFRRRFNQYTSWVNESEPN--------VMWLSGLHIPESYLTALVQATCRKNGWPLDRSTLYTQVTSFRTPEEVTERPGQGCFISGLYLEGAD 4455 HSP 2 Score: 54.299 bits (129), Expect = 8.981e-6 Identity = 83/438 (18.95%), Postives = 180/438 (41.10%), Query Frame = 3 Query: 1602 FLPE----SADTSSIDEVNAAYE-IVKVIDCLDFAK---EENDEWDAAIKRYEERIDRVESRIASHLRDLLGQSKNANEMFRYFSRFNALFVRPHIRGAIGEYQTQLIQRVKDDIEALHNKFKVQYASSTACKMSKVRDLPPVSGSIIWVRQILRQLNAYMKR---VEDVL----GKDWAQHIEGQKLKADGESFKLKLNTSELFEEWSKKVAEKSLSVAG-SIFNVESTRTVVTVRDREPQKITVLKLKVNFLPDVITLAKEVRNMRALGFRTPLSIVNKAHSANQLYPFAISLIESVRTYESTCSKIEEHKMQNISLLTAGLRKDVQLCIHEGVQ-ITWESYRLDQYVQKLAELVFSFQEKVDDLVIVIKEIDFNVKALETC--------------SYNKQTFEEILIRIQEAVDNMSLHQFSNLAQWVSNLDSLV 2822 F PE + D ID+V + +V+ ++ L F + + +W ++ ++ + +E + + + ++A F +F + R I + ++++ +++ +++ F + K + PPV+GSI W R + ++ + R +E++L GK +++E + K+K + +E W + + S+ S+ N + ++ T VNF P++ + E ++M +GF N A ++ + + + YE + E ++Q LL +R DV G + + W S + Y+ + + + F+ V+ + K+ID + A+E+ S K+ FE I I + VD + ++S + Q ++ ++ LV Sbjct: 513 FGPELKAVTGDPKRIDDVLRRVDGLVRPMENLSFDPFNIKNSQQWKMVMEDFKNEVHAIEGEAINFIDESFKTLRSAEAAFDMLLKFKHIRSREAINKQMMMKFNDILEQYAKEVDIVNSLFLKHLDNPPLYK-----NHPPVAGSIYWERSLFYRIKHTIVRFLEMEEMLSCERGKAVTKYLEVAR--------KMKEYEDKKYEMWKENTDQNLPSLLKRSLLNAD--------QNEADNGDTDFHFSVNFAPELWEIITETKHMEQMGFSVGELPRNVALQEDKFLRYTDDMKHMIAAYEKLMGSLSEAEIQ---LLDEHIR-DVWKVFRSGYRRLNWNSLGIGDYITRCNQAISKFESLVNKIQKNAKDIDLKLSAIESANLFKFMAKTTGTDLSGVKEFFEYIDIERAKDVDILE-RKYSTIGQLLTKIEGLV 924
BLAST of Cytoplasmic dynein 1 heavy chain 1 vs. Ensembl Xenopus
Match: DNAH10 (dynein axonemal heavy chain 10 [Source:NCBI gene;Acc:100492440]) HSP 1 Score: 1380.16 bits (3571), Expect = 0.000e+0 Identity = 959/3374 (28.42%), Postives = 1702/3374 (50.44%), Query Frame = 3 Query: 3927 EEAVNIIQILEGKFNRLKEERENVQKAKEALELTEIGVKP--ISEEKVTNALSELHDLKNVWNELKSIWEKIRDMKETPWLSVQPRKLRQDIENLTAQLKELPNSFKQYASFEHVRTLLKMYMKVNASIVELKSEAIKERHWRMLMRKLNVSWSLNE--LQLGKVWDIDLVKNEEIIREVLAIAQGEKALEEYLRQITEVWKNYVLELTNY----QSKSKIIKGWDDLFNKVKEHINNVTSMKASPYFKQFEEEATAWEDRLNKINALFDVWIDVQRRWIYLDGIFAGSADIKVLLPVESQRFQSVSTEFLGLMKKVQKSPLVTDVLNIANVQRQLERLADLLGKIQKSLGEYLERQRSSFPRFYFVGDEDLLEIIGNSXXXXXXXXXXXXMFAGVHSIILSED---EKVILGMMSKEGEELRFISPVSIIEHPRINDWLTAMEKEMRVSLAKYLNVAVKEISGWR---TESNIDKDKFMVWLDKYQAQIVVLAAQITWSEAVEASL-----ASGVSLESTMTVVHSTLNMLADTVLYEQPPVRRRKLEHLIIEYVHQRDVLRALHNDGVSSNKNFDWMSQMRFYFDPKQTDPLHQLSIHVANAKFHYGFEYLGVCDRLVQTPLTDRCYLTMTQALEARLGGSPFGPAGTGKTESVKSLGNQLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLSAVSQQIQGIQEALRELMVSKKDSINVELLGKQVHVNPDMAIFITMNPGYAGRSNLPDNLKKLFRSLAMTQPDRQLIAQVMLYSQGFRTAEVLAGKVVPFFKLCDEQLSPQSHYDFGLRALKSVLVSAGNVKRDRIKQEKEKIVARGEEINETAIAEQLPEQEILIQSVMETMVPKLIADDIPLLYSLLTDVFPGVEYRQAEMKRLREELRK-VSENKFLVYSDEPNTAGYLWVEKVLQLYQITTIHHGLMMVGPSGSGKTMACRVLLQALENIDGIEGVAHIIDPKSISKDSLYGYMDPNTREWTDGLFTHILRRIIDSVRGESNKRQWIVFDGDVDPEWVENLNSVLDDNKLLTLPNGERLAIPPNVRIMFEVQDLKYATLATVSRCGMVWFSEEVLTTGMILTHFLNELKKVQVMEGEEDFSVNQGDTGADADSKISSSPIIQLQTQVSSILAPFFTEDGLIAKCLDYSTTLEHIMDFTRLRALTSLFSMIKQSIRNMIEYNQSHSDFPLNNEQIENYVAKS-LISSVVWSMSGDSKLKVREQLSQYIKNISTV----DLPTVGGI-------KNIIDFEVNIQGT-WVAWSNKVPQIEVETHKITATDVVVPTMDTVRHEALLYTWLAEHRPVLLCGPPGSGKTMTLFSALRCLPDMEVVGLNFSSATTPELMLKTFDQYCEYRKTPNGIVLAPQQLNKWLIFFCDEINLPDMDKYGTQRVISFLRQMVEHHGFY-RITDMQWVSFERIQFVGACNPPTDPGRKPLSHRFLRHVPVVYVDYPGETSLKQIYSTFNRAMLRML-PSLRGYADTLTNAMVEFFLKTQERFTHDMQP-----HYIYSPREMTRWVRGIHEALKPLESLSVEGLVRIWAHEALRLFQDRLVEEDERHWTDDNINEVALKHFPNINKEEALKRPILYSNWLS--KDYSAVTQEELRDYVKAR------LKVFYEEELDVPLVLFNQVLDHVLRIDRVFRQPQGHLLLIGVSGAGKTTLSRFVSWINGLSVFQVKVHNKYTAEDFDEDLRNVLRRSGCKGEKITFIMDESNVMDSSFLERMNTLLANGEVPGLFEGDELTTLMTQCKEGAIREGLMIDSQEELYKWFTQQICRNLHVVFTMNPSADGLKDKASTSPALFNRCVLNWFGDWSLEAYFQVGKEFTNRLDLERTDYKVPDTLPCIAEGLLPQNPIYRDVVVNALVFVHQTMHQANVRVQKRGGRTAAITPRHYLDLIAHYMKLSAEKRADLEEQQLHLNNGLKKIEQTVDQVEVMQRSLTKKRQELENMNEAANAKLKQMVQDQQEAEQKKTTGQALKEELAKQEQFVNEKQKTVKQELDQVEPTVNEAKQAVQNIRKKDIQEIKAMKNPPNAVKMAVESICLLLGEKTTDWQSILKVIIKDTFVTSILNFNTDDVSDNTRETMKKKYLSNPDYNFEKVNKASNACGPMVKWVLAQISYADILKRVEPLRNELTELSDAAEQNRKKSQETEDLIAQLEKSIAKYTEEYATLISQAQTIKSDLASVESKVGRSVALLGSLSSERTRWDSGSETFKAQMATINGDCLLSSAFMAYGGYFDQHMRTSL-FNTWCHHLSEADILFR----SDLARVEYLSNPDDRL-RWQANSLPADDLCVENAIILRRYNRYPLIIDPSGQATTFLLNEYKEKKITKTSFLDDSFRKTLESALRFGTPLLVQDVESY-DPILNPVLNREVRRTGGRTLITLGDQDIDLSPTFTIFLSTRDPSVEFAPDICSRVTFVNFTVTRSSLQNQCLNAVLKIERPDIDQKRSDLLKAQGEFQLKLRHLEKDLLQSLNEAQGNLLENDKIIARLETLKREAADVAKKVEETDVVMQEVESVSTEYVPLAQSCSNIYFTLEAMNQIHFLYQYSLQLMLDIFSSVLINN-PELTNVKAASDRLKIITKNLFQVTYNRLARGMLHEDQITFA-TILARI-FLKGSTPIGFLENEFQHFLRSQEATITSSDSNKQDNLGLTLHQDQIDSVKRLKKL--KVFAKIEEKV-KSTKDIKNWTLTVTPESNVPELWVDDNNYNDEKLSKIAKGMYNLLIIQAIRPDRLLASTQKFIASVLGDTFTESVRGTLDLASIVEVEVTACVPILLCAVQGYDPSGRVEDLASEQ---GKQLTGIAIGSAEGFSQAEKAINSAAKTGKWVMLKNVHLATSWLVSLEKKIHSL-QAHPNFRLFLTMEITPKLPVNLLRAGRVLVFEPPPGIKANLLRTLSSINNQRM-SKEPVERSRLYFLLAWLNAIVQERLRYVPLGYSKKYEFGESDFKCALDTIDTWVDGAAMGRTNLPPEKIPWVALQTLLGSCIYGGKIDNAFDQRLLNSFLGYLFTEKCFDHNFALVSDADDGSNIAFPESTKHTDILQWVHKLPDLQTPSWLGLPNSAEKVLLTNLGQSLIGNILKMQQSLEDDEELVVGQSKTKRTIEVGDGRPAWMRQLYQSTQT----WLQILPKSVTPLQRTIENIKDPMYRCFEREVNSGCNLLASVRKDLEDVAEVCKGAKKPTNHHRSMMADLAKGIIPKMWIRYAIPPGLTVIQWIQDFADRIKQLLHISDTAAKSGVIALRSIQVWLGGLFMAEAYITATRQSVAQNNKWALEELFLDVELGEGKVDSNT-------CVITGLRLMGSE 13817 ++ + ++ E + + +++R+ + A++ +L I + P I +K L +++++ N + K W +T W ++ + L I+ ++L + ++ + +K + + +++LK+EA+++RHW+ LM K + +N L ++ ++L K + I +++A A E ++E+ +++I + W+N + Y Q + I+ D++ + ++ N+ S+ S + F WE L+ I + +VW+ VQR+W+YL+ IF G DI+ LP E+++F ++ F +M + K P++ +N L+ L++ L + QKSL +YL+ +R++FPRF+F+ D++LL I+G+S + K M+ + S+ E E M+S EGE + F V+ R+ DW+T + +EMR + N + + + +R +S +D W+ YQ +V+ Q+ W+ VE +L++ +H ++ L + R+K ++I VH RD++ D + + F+W SQ+RFY+D ++ D +L++ F YG+EY+G+ RLV TPLTDR YLT+TQAL LGG+P GPAGTGKTE+ K L LG +V NC E D++A+G+IF GL Q GAWGCFDEFNR++ +LS +S QIQ I+ AL + + G+++ ++ M IFITMNPGYAGR+ LP+++K LFR + + PD Q I ++ML+S+GF A+ LA K+ +KL EQLS Q HYDFGLRALKSVLV AG +KR + L E +L++++ + +PK + +D+PL L++D+FPG++ + + + + + EN +++ + V+KV+Q+Y+ H M+VGP+G GK++ L A + G+ + ++PK++S LYG +DP TR+WTDG+ ++I R I E +R++I+FDGDVD WVEN+NSV+DDNKLLTL NGER+ + P+ ++FEV DL+YA+ ATVSRCGMV+ + L ++N + SK Q S+L+ F + + C++ +E I D + L ++ + Q+ NM+ + D L E + V + I ++ WS+ R + +YIK ++++ D + G I DF + + W+ WS VP+ + + D++VPT+DT R LL + RPV+L G G+ KT T + LR L ++ +NFSS TT + + + E R N P + K L+ F D++N+P +D+YGTQ+ I+ L+ ++E G Y R ++ + F+ A GR + RF+ V V +P E SL IYS+ + + ++ D LT +E + + D+ P HYI++ R+++R G+ P +V +VR+W +E LR+F DRLV E+++ +I + +HF + E A + PIL+ ++ + + E+++DY A+ L+ + E + + LVLF+ L+H+ RI R+ R +GH LL+GV G+GK +L+R ++ G VF++ + Y F EDLRN+ + G + +K+ F+ +++V + FLE +N +L +G VP LF DE ++++Q ++ A + G+ ++E ++++F + NLH+V M+P D L+ + P L N ++WF W +A + V F L + + P V +V VH ++ + + + Q++ R+ +TP++YLD I Y +L EK Q L GL K+++ Q+ + L +++ L + A A L ++ + AE+K+ + E+ +Q + + +++ + L + P + AK +Q + K D+ EI++ PP AV++ E I ++ G K W+S ++ +F+ S++ + D ++ + + ++ +L + FE++ S A M+K+V A + Y D+ K ++P R ++ +L +++ ++ + ++ ++ + E+Y I++ Q ++ + +E ++ + L+ L SE RW + E K + + GDCLL SAF++Y G F+ R + + W + DIL R S R+E L D + RW + LP D+L ++N I+ R +R+PL IDP QA ++ + ++ + +SF D F K LE A+++G P L QDV+ Y DP+++ VL + ++ GR I LGD+++D P F ++L+T+ + +++P + + +N+TVT L++Q L+ ++ ER +++++R +L++ E + L+ LE LL+ L + GN+L+N +++ LE K +A +V++K++ + +++ + Y P A+ + ++F L M ++ +YQYSL L +F L + P+ +K RLK I L YN G+ + ++ F+ + +I G P + E FL+ I+ S ++ Q D + RL +L +F + V + + K W T E L YND KLS K LL+++ R DR+ + ++ +G+ + + + +I E V PI+ G DP+ + LA G +L +A+G + A + + +A G+W+ML+N HL WL LEK + + + HP+FRL+LT + T + P+ +L+ +V EPP G+K N+ T I+++ + S + L ++LA+ +A+VQER ++ +G++ Y+F ESDF+ ++ ++T++ A KIPW +L+ L+G +YGG+ ++FD+R+L +++ + FD ++ + PE T ++ + LP TP GL ++AE T + + ++L++Q E G S+ + +V + Q++ Q L+I P +V LQ E+ L+ + + L ++ G ++ + L G IP +W R A ++ W+ F R Q + + + +WL GL + E+Y+TA Q+ + N W L+ L ++ + C I+GL L G++ Sbjct: 1227 DKGLQVLSAFEKELAKYEKDRQELANAEKLFDLP-ITMYPELIQIQKEMKGLQQIYEIYNAQKQAKEEW------SQTLWANLNVQILLDGIDGFLKAFRKLSKDIRSLPVAFYLESKMKEFKESIPLLLDLKNEALRDRHWKELMTKTGTDFEMNPETFTLENMFAMELHKYADAISDIVASAVKELSIEKGVKEILDTWENMKFTVQRYIKGTQDRGSILGTVDEILQILDDNAMNLQSISGSRFVGPFLNTVQQWEKTLSLIGEVIEVWMVVQRKWMYLESIFIG-GDIRSQLPDEAKKFDNIDRIFKRIMSETVKDPVIKRCCQASNRLSDLQNLSEGLERCQKSLNDYLDSKRNAFPRFFFISDDELLSILGSSDPTCVQEHIIK-MYDNIASLKFQEGDNGEMKATAMVSAEGEVMPFRQVVA--AEGRVEDWMTTVLQEMRRT-----NRLITKEAIFRYCEDKSRVD------WMLLYQGMVVLAGNQVWWTWEVEDVFRKVKKGEKQALKNYAKKMHQQIDELVTRITKPLSKNDRKKYNTVLIIDVHARDIVDIFVRDSIMDAREFEWESQLRFYWD-REPD---ELNVRQCTGTFAYGYEYMGLNGRLVITPLTDRIYLTLTQALSMYLGGAPAGPAGTGKTETTKDLAKALGLLCVVTNCGEGMDYKAVGKIFSGLAQCGAWGCFDEFNRIDASVLSVISSQIQTIRNALIHHLK------RFQFEGQEIALDARMGIFITMNPGYAGRTELPESVKALFRPVVVIVPDLQQICEIMLFSEGFLQAKNLAKKMTVLYKLAREQLSKQHHYDFGLRALKSVLVMAGELKRG---------------------SPDLNEDVVLMRALRDMNLPKFVFEDVPLFLGLISDLFPGLDCPRVRYPDFNDAVEEALQENNYILLPTQ--------VDKVVQMYETMLTRHTTMVVGPTGGGKSVVINTLCLAQTKL-GLVTKLYTLNPKAMSVIELYGILDPATRDWTDGVLSNIFREINKPT--EKKERRYILFDGDVDALWVENMNSVMDDNKLLTLANGERIRLQPHCALLFEVGDLQYASPATVSRCGMVFVDPKNLKYMPYWQKWVN-----------------------NRQSK-----------QEQSVLSKLF--EKYVPHCIE--MIVEGITDGKQGEKLKTI---VPQTDLNMVTQLSTMLDALLEKEVDDADVLECYFIEAMYWSLGATLLETGRIKFDEYIKRLASMSAAYDESILAGPGELPYQQPTIYDFHFDGEKKKWIPWSKLVPKY-IHKPEEKFIDILVPTVDTTRTTWLLEQMVKIKRPVVLVGESGTSKTATTLNLLRNLNTDMLLSINFSSRTTSMDIQRNLEANVEKRTKDN---YGPP-MGKRLLVFMDDMNMPKVDEYGTQQPIALLKLLLEKGGMYDRGKELNCKYLRDLGFIAAMGK-AGGGRNEVDTRFISLFSVFNVLFPSEESLSLIYSSILKGHTALFNEEVQAICDKLTFCTLELY----KMIVRDLPPTPSKFHYIFNLRDLSRVYNGL-VLTTPERFQTVAQMVRVWRNENLRVFHDRLVNEEDK-LVQGHIKHLIEEHF-QASLEHATRDPILFGDYRTAMSEGEPRVYEDIQDYEAAKALFQEILEEYNESKTKMNLVLFDDALEHLTRIHRIIRMDRGHALLVGVGGSGKQSLARLAAYAAGYEVFEIVLSRGYGENSFREDLRNLYIKLGLENKKMIFLFTDAHVAEEGFLELINNMLTSGMVPALFPDDEKESVLSQIRDEATKHGVG-PAKESIWQFFVNKSANNLHIVLGMSPVGDTLRTRCRNFPGLVNNTGIDWFLPWPPQALYAVANSFLGDNSLIPSQHSEP--------------------VTGHVVMVHDSVGKFSKKFQQKLRRSNYVTPKNYLDFINTYSRLLEEKNQYNLAQCKRLEGGLDKLKEATVQLAELNVKLAEQKVVLAEKSSACEALLDEISTNTTIAEEKRKLAEEKAAEIEEQNKVIAVEKQEAESALAEALPILEAAKLELQKLDKSDVTEIRSFAKPPRAVQVVCECILVMRGYKEISWKSAKGMMSDPSFLKSLMEIDFDAITQHQVKAVRG-FLKTLNTTFEEMEAISKAGLGMLKFVEAVMGYCDVAKEIKPKREKVAKLERNYYMSKRDLEKIQAELSTIQNELKALGEKYEAAITEKQKLQEEAEVMERRLIAADKLISGLGSENKRWTNDLEELKVRRVKLLGDCLLCSAFLSYEGAFNWDFRKEMVYTEW-----QQDILAREIPLSQPFRIESLLTDDVEISRWGSEGLPPDELSIQNGILTTRASRFPLCIDPQQQALNWIKRKEEKNNLKISSFNDPDFLKQLEMAIKYGFPFLFQDVDEYIDPVIDNVLEKNIKGAQGRQFIILGDKEVDYDPNFKLYLNTKLSNPKYSPSVFGKAMVINYTVTLKGLEDQLLSVIVGFERRELEEQRENLIQETSENKKLLKDLEDSLLRELATSTGNMLDNVELVHTLEETKAKATEVSEKLKLAEKTAVDIDKLRDGYRPAAKRGAILFFVLSEMALVNSMYQYSLSSFLAVFDHSLRKSLPDGILMK----RLKNIMDTLTYNVYNYGCTGLFEKHKLLFSFNMTVKIEQADGRVP----QEELDFFLK---GNISLEKSKRKKPCSWIPDQGWEDII-RLSELFPSMFGSLPSDVERCEAEWKAWYDLDTLEQYPYPL-----GYND-KLSDFQK----LLLLRCFRVDRVYRAVSDYVTVTMGEKYVQP--PVISFEAIFEQSVPTS-PIVFILSPGSDPASDLMKLAERSGFGGNRLKFLAMGQGQE-KVALQLLETAVFRGQWLMLQNCHLLVKWLKDLEKALEMIKKPHPDFRLWLTTDPTKEFPIGILQKSLKVVTEPPNGLKLNMRATYFKISHEALDSCQHSAFKSLVYVLAFFHAVVQERRKFGKIGWNVPYDFNESDFQVCMEILNTYLTKAFQQHDT----KIPWGSLKYLIGEVMYGGRAIDSFDRRILTTYMDEYLGDFIFDTFQLFHFYKNEEVDYRIPEGTTKDAFVEAIESLPLANTPEVFGLHSNAEIGYYTQAARDMWTHLLELQPQ---TGESSTGISRDEYIGQVAKDIENKLPQIFDLDQIRKNLGLEISPTTVVLLQ----------------ELERFNKLIIRMSRSLVELQRALAGEVGMSSELDEVARALFNGQIPNIWRRLAPDTLKSLGNWMIHFRRRFNQYTSWVNESEPN--------VMWLSGLHIPESYLTALVQATCRKNGWPLDRSTLYTQVTSFRTPEEVTERPGQGCFISGLYLEGAD 4398 HSP 2 Score: 54.6842 bits (130), Expect = 6.262e-6 Identity = 80/380 (21.05%), Postives = 156/380 (41.05%), Query Frame = 3 Query: 1764 IASHLRDLLGQSKNANEMFRYFSRFNALFVRPHIRGAIGEYQTQLIQRVKDDIEALHNKFKVQYASSTACKM----SKVRDLPPVSGSIIWVRQILRQLNAYMKR---VEDVL----GKDWAQHIEGQKLKADGESFKLKLNTSELFEEWSKKVAEKSLSVAG-SIFNVESTRTVVTVRDREPQKITVLKLKVNFLPDVITLAKEVRNMRALGFRTPLSIVNKAHSANQLYPFAISLIESVRTYESTCSKIEEHKMQNISLLTAGLRKDVQLCIHEGVQ-ITWESYRLDQYVQKLAELVFSFQEKVDDLVIVIKEIDFNVKALETC--------------SYNKQTFEEILIRIQEAVDNMSLHQFSNLAQWVSNLDSLV 2822 L+ + G K +++ R R + L VRP + + + Q+ K +E N+ V +S K ++ PPV+GSI W R + ++ + R +E++L GK +++E + K+K + +E W + + S+ S+ N + ++ T VNF P++ + E ++M +GF N A ++ + + + YE + E ++Q LL +R DV G + + W S + Y+ + + + F+ V+ + K+ID + A+E+ S K+ FE I I + VD + ++S + Q ++ ++ LV Sbjct: 513 FGPELKAVTGDPKRIDDVLR---RVDGL-VRPMENLSFDPFNIKNSQQWKMVMEDFKNEVHVDIVNSLFLKHLDNPPLYKNHPPVAGSIYWERSLFYRIKHTIVRFLEMEEMLSCERGKAVTKYLEVAR--------KMKEYEDKKYEMWKENTDQNLPSLLKRSLLNAD--------QNEADNGDTDFHFSVNFAPELWEIITETKHMEQMGFSVGELPRNVALQEDKFLRYTDDMKHMIAAYEKLMGSLSEAEIQ---LLDEHIR-DVWKVFRSGYRRLNWNSLGIGDYITRCNQAISKFESLVNKIQKNAKDIDLKLSAIESANLFKFMAKTTGTDLSGVKEFFEYIDIERAKDVDILE-RKYSTIGQLLTKIEGLV 867
BLAST of Cytoplasmic dynein 1 heavy chain 1 vs. Ensembl Xenopus
Match: DNAH10 (dynein axonemal heavy chain 10 [Source:NCBI gene;Acc:100492440]) HSP 1 Score: 1375.92 bits (3560), Expect = 0.000e+0 Identity = 959/3374 (28.42%), Postives = 1702/3374 (50.44%), Query Frame = 3 Query: 3927 EEAVNIIQILEGKFNRLKEERENVQKAKEALELTEIGVKP--ISEEKVTNALSELHDLKNVWNELKSIWEKIRDMKETPWLSVQPRKLRQDIENLTAQLKELPNSFKQYASFEHVRTLLKMYMKVNASIVELKSEAIKERHWRMLMRKLNVSWSLNE--LQLGKVWDIDLVKNEEIIREVLAIAQGEKALEEYLRQITEVWKNYVLELTNY----QSKSKIIKGWDDLFNKVKEHINNVTSMKASPYFKQFEEEATAWEDRLNKINALFDVWIDVQRRWIYLDGIFAGSADIKVLLPVESQRFQSVSTEFLGLMKKVQKSPLVTDVLNIANVQRQLERLADLLGKIQKSLGEYLERQRSSFPRFYFVGDEDLLEIIGNSXXXXXXXXXXXXMFAGVHSIILSED---EKVILGMMSKEGEELRFISPVSIIEHPRINDWLTAMEKEMRVSLAKYLNVAVKEISGWR---TESNIDKDKFMVWLDKYQAQIVVLAAQITWSEAVEASL-----ASGVSLESTMTVVHSTLNMLADTVLYEQPPVRRRKLEHLIIEYVHQRDVLRALHNDGVSSNKNFDWMSQMRFYFDPKQTDPLHQLSIHVANAKFHYGFEYLGVCDRLVQTPLTDRCYLTMTQALEARLGGSPFGPAGTGKTESVKSLGNQLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLSAVSQQIQGIQEALRELMVSKKDSINVELLGKQVHVNPDMAIFITMNPGYAGRSNLPDNLKKLFRSLAMTQPDRQLIAQVMLYSQGFRTAEVLAGKVVPFFKLCDEQLSPQSHYDFGLRALKSVLVSAGNVKRDRIKQEKEKIVARGEEINETAIAEQLPEQEILIQSVMETMVPKLIADDIPLLYSLLTDVFPGVEYRQAEMKRLREELRK-VSENKFLVYSDEPNTAGYLWVEKVLQLYQITTIHHGLMMVGPSGSGKTMACRVLLQALENIDGIEGVAHIIDPKSISKDSLYGYMDPNTREWTDGLFTHILRRIIDSVRGESNKRQWIVFDGDVDPEWVENLNSVLDDNKLLTLPNGERLAIPPNVRIMFEVQDLKYATLATVSRCGMVWFSEEVLTTGMILTHFLNELKKVQVMEGEEDFSVNQGDTGADADSKISSSPIIQLQTQVSSILAPFFTEDGLIAKCLDYSTTLEHIMDFTRLRALTSLFSMIKQSIRNMIEYNQSHSDFPLNNEQIENYVAKS-LISSVVWSMSGDSKLKVREQLSQYIKNISTV----DLPTVGGI-------KNIIDFEVNIQGT-WVAWSNKVPQIEVETHKITATDVVVPTMDTVRHEALLYTWLAEHRPVLLCGPPGSGKTMTLFSALRCLPDMEVVGLNFSSATTPELMLKTFDQYCEYRKTPNGIVLAPQQLNKWLIFFCDEINLPDMDKYGTQRVISFLRQMVEHHGFY-RITDMQWVSFERIQFVGACNPPTDPGRKPLSHRFLRHVPVVYVDYPGETSLKQIYSTFNRAMLRML-PSLRGYADTLTNAMVEFFLKTQERFTHDMQP-----HYIYSPREMTRWVRGIHEALKPLESLSVEGLVRIWAHEALRLFQDRLVEEDERHWTDDNINEVALKHFPNINKEEALKRPILYSNWLS--KDYSAVTQEELRDYVKAR------LKVFYEEELDVPLVLFNQVLDHVLRIDRVFRQPQGHLLLIGVSGAGKTTLSRFVSWINGLSVFQVKVHNKYTAEDFDEDLRNVLRRSGCKGEKITFIMDESNVMDSSFLERMNTLLANGEVPGLFEGDELTTLMTQCKEGAIREGLMIDSQEELYKWFTQQICRNLHVVFTMNPSADGLKDKASTSPALFNRCVLNWFGDWSLEAYFQVGKEFTNRLDLERTDYKVPDTLPCIAEGLLPQNPIYRDVVVNALVFVHQTMHQANVRVQKRGGRTAAITPRHYLDLIAHYMKLSAEKRADLEEQQLHLNNGLKKIEQTVDQVEVMQRSLTKKRQELENMNEAANAKLKQMVQDQQEAEQKKTTGQALKEELAKQEQFVNEKQKTVKQELDQVEPTVNEAKQAVQNIRKKDIQEIKAMKNPPNAVKMAVESICLLLGEKTTDWQSILKVIIKDTFVTSILNFNTDDVSDNTRETMKKKYLSNPDYNFEKVNKASNACGPMVKWVLAQISYADILKRVEPLRNELTELSDAAEQNRKKSQETEDLIAQLEKSIAKYTEEYATLISQAQTIKSDLASVESKVGRSVALLGSLSSERTRWDSGSETFKAQMATINGDCLLSSAFMAYGGYFDQHMRTSL-FNTWCHHLSEADILFR----SDLARVEYLSNPDDRL-RWQANSLPADDLCVENAIILRRYNRYPLIIDPSGQATTFLLNEYKEKKITKTSFLDDSFRKTLESALRFGTPLLVQDVESY-DPILNPVLNREVRRTGGRTLITLGDQDIDLSPTFTIFLSTRDPSVEFAPDICSRVTFVNFTVTRSSLQNQCLNAVLKIERPDIDQKRSDLLKAQGEFQLKLRHLEKDLLQSLNEAQGNLLENDKIIARLETLKREAADVAKKVEETDVVMQEVESVSTEYVPLAQSCSNIYFTLEAMNQIHFLYQYSLQLMLDIFSSVLINN-PELTNVKAASDRLKIITKNLFQVTYNRLARGMLHEDQITFA-TILARI-FLKGSTPIGFLENEFQHFLRSQEATITSSDSNKQDNLGLTLHQDQIDSVKRLKKL--KVFAKIEEKV-KSTKDIKNWTLTVTPESNVPELWVDDNNYNDEKLSKIAKGMYNLLIIQAIRPDRLLASTQKFIASVLGDTFTESVRGTLDLASIVEVEVTACVPILLCAVQGYDPSGRVEDLASEQ---GKQLTGIAIGSAEGFSQAEKAINSAAKTGKWVMLKNVHLATSWLVSLEKKIHSL-QAHPNFRLFLTMEITPKLPVNLLRAGRVLVFEPPPGIKANLLRTLSSINNQRM-SKEPVERSRLYFLLAWLNAIVQERLRYVPLGYSKKYEFGESDFKCALDTIDTWVDGAAMGRTNLPPEKIPWVALQTLLGSCIYGGKIDNAFDQRLLNSFLGYLFTEKCFDHNFALVSDADDGSNIAFPESTKHTDILQWVHKLPDLQTPSWLGLPNSAEKVLLTNLGQSLIGNILKMQQSLEDDEELVVGQSKTKRTIEVGDGRPAWMRQLYQSTQT----WLQILPKSVTPLQRTIENIKDPMYRCFEREVNSGCNLLASVRKDLEDVAEVCKGAKKPTNHHRSMMADLAKGIIPKMWIRYAIPPGLTVIQWIQDFADRIKQLLHISDTAAKSGVIALRSIQVWLGGLFMAEAYITATRQSVAQNNKWALEELFLDVELGEGKVDSNT-------CVITGLRLMGSE 13817 ++ + ++ E + + +++R+ + A++ +L I + P I +K L +++++ N K W +T W ++ + L I+ ++L + ++ + +K + + +++LK+EA+++RHW+ LM K + +N L ++ ++L K + I +++A A E ++E+ +++I + W+N + Y Q + I+ D++ + ++ N+ S+ S + F WE L+ I + +VW+ VQR+W+YL+ IF G DI+ LP E+++F ++ F +M + K P++ +N L+ L++ L + QKSL +YL+ +R++FPRF+F+ D++LL I+G+S + K M+ + S+ E E M+S EGE + F V+ R+ DW+T + +EMR + N + + + +R +S +D W+ YQ +V+ Q+ W+ VE +L++ +H ++ L + R+K ++I VH RD++ D + + F+W SQ+RFY+D ++ D +L++ F YG+EY+G+ RLV TPLTDR YLT+TQAL LGG+P GPAGTGKTE+ K L LG +V NC E D++A+G+IF GL Q GAWGCFDEFNR++ +LS +S QIQ I+ AL + + G+++ ++ M IFITMNPGYAGR+ LP+++K LFR + + PD Q I ++ML+S+GF A+ LA K+ +KL EQLS Q HYDFGLRALKSVLV AG +KR + L E +L++++ + +PK + +D+PL L++D+FPG++ + + + + + EN +++ + V+KV+Q+Y+ H M+VGP+G GK++ L A + G+ + ++PK++S LYG +DP TR+WTDG+ ++I R I E +R++I+FDGDVD WVEN+NSV+DDNKLLTL NGER+ + P+ ++FEV DL+YA+ ATVSRCGMV+ + L ++N + SK Q S+L+ F + + C++ +E I D + L ++ + Q+ NM+ + D L E + V + I ++ WS+ R + +YIK ++++ D + G I DF + + W+ WS VP+ + + D++VPT+DT R LL + RPV+L G G+ KT T + LR L ++ +NFSS TT + + + E R N P + K L+ F D++N+P +D+YGTQ+ I+ L+ ++E G Y R ++ + F+ A GR + RF+ V V +P E SL IYS+ + + ++ D LT +E + + D+ P HYI++ R+++R G+ P +V +VR+W +E LR+F DRLV E+++ +I + +HF + E A + PIL+ ++ + + E+++DY A+ L+ + E + + LVLF+ L+H+ RI R+ R +GH LL+GV G+GK +L+R ++ G VF++ + Y F EDLRN+ + G + +K+ F+ +++V + FLE +N +L +G VP LF DE ++++Q ++ A + G+ ++E ++++F + NLH+V M+P D L+ + P L N ++WF W +A + V F L+P + + V +V VH ++ + + + Q++ R+ +TP++YLD I Y +L EK Q L GL K+++ Q+ + L +++ L + A A L ++ + AE+K+ + E+ +Q + + +++ + L + P + AK +Q + K D+ EI++ PP AV++ E I ++ G K W+S ++ +F+ S++ + D ++ + + ++ +L + FE++ S A M+K+V A + Y D+ K ++P R ++ +L +++ ++ + ++ ++ + E+Y I++ Q ++ + +E ++ + L+ L SE RW + E K + + GDCLL SAF++Y G F+ R + + W + DIL R S R+E L D + RW + LP D+L ++N I+ R +R+PL IDP QA ++ + ++ + +SF D F K LE A+++G P L QDV+ Y DP+++ VL + ++ GR I LGD+++D P F ++L+T+ + +++P + + +N+TVT L++Q L+ ++ ER +++++R +L++ E + L+ LE LL+ L + GN+L+N +++ LE K +A +V++K++ + +++ + Y P A+ + ++F L M ++ +YQYSL L +F L + P+ +K RLK I L YN G+ + ++ F+ + +I G P + E FL+ I+ S ++ Q D + RL +L +F + V + + K W T E L YND KLS K LL+++ R DR+ + ++ +G+ + + + +I E V PI+ G DP+ + LA G +L +A+G + A + + +A G+W+ML+N HL WL LEK + + + HP+FRL+LT + T + P+ +L+ +V EPP G+K N+ T I+++ + S + L ++LA+ +A+VQER ++ +G++ Y+F ESDF+ ++ ++T++ A KIPW +L+ L+G +YGG+ ++FD+R+L +++ + FD ++ + PE T ++ + LP TP GL ++AE T + + ++L++Q E G S+ + +V + Q++ Q L+I P +V LQ E+ L+ + + L ++ G ++ + L G IP +W R A ++ W+ F R Q + + + +WL GL + E+Y+TA Q+ + N W L+ L ++ + C I+GL L G++ Sbjct: 1155 DKGLQVLSAFEKELAKYEKDRQELANAEKLFDLP-ITMYPELIQIQKEMKGLQQIYEIYNAQKVSKEEW------SQTLWANLNVQILLDGIDGFLKAFRKLSKDIRSLPVAFYLESKMKEFKESIPLLLDLKNEALRDRHWKELMTKTGTDFEMNPETFTLENMFAMELHKYADAISDIVASAVKELSIEKGVKEILDTWENMKFTVQRYIKGTQDRGSILGTVDEILQILDDNAMNLQSISGSRFVGPFLNTVQQWEKTLSLIGEVIEVWMVVQRKWMYLESIFIG-GDIRSQLPDEAKKFDNIDRIFKRIMSETVKDPVIKRCCQASNRLSDLQNLSEGLERCQKSLNDYLDSKRNAFPRFFFISDDELLSILGSSDPTCVQEHIIK-MYDNIASLKFQEGDNGEMKATAMVSAEGEVMPFRQVVA--AEGRVEDWMTTVLQEMRRT-----NRLITKEAIFRYCEDKSRVD------WMLLYQGMVVLAGNQVWWTWEVEDVFRKVKKGEKQALKNYAKKMHQQIDELVTRITKPLSKNDRKKYNTVLIIDVHARDIVDIFVRDSIMDAREFEWESQLRFYWD-REPD---ELNVRQCTGTFAYGYEYMGLNGRLVITPLTDRIYLTLTQALSMYLGGAPAGPAGTGKTETTKDLAKALGLLCVVTNCGEGMDYKAVGKIFSGLAQCGAWGCFDEFNRIDASVLSVISSQIQTIRNALIHHLK------RFQFEGQEIALDARMGIFITMNPGYAGRTELPESVKALFRPVVVIVPDLQQICEIMLFSEGFLQAKNLAKKMTVLYKLAREQLSKQHHYDFGLRALKSVLVMAGELKRG---------------------SPDLNEDVVLMRALRDMNLPKFVFEDVPLFLGLISDLFPGLDCPRVRYPDFNDAVEEALQENNYILLPTQ--------VDKVVQMYETMLTRHTTMVVGPTGGGKSVVINTLCLAQTKL-GLVTKLYTLNPKAMSVIELYGILDPATRDWTDGVLSNIFREINKPT--EKKERRYILFDGDVDALWVENMNSVMDDNKLLTLANGERIRLQPHCALLFEVGDLQYASPATVSRCGMVFVDPKNLKYMPYWQKWVN-----------------------NRQSK-----------QEQSVLSKLF--EKYVPHCIE--MIVEGITDGKQGEKLKTI---VPQTDLNMVTQLSTMLDALLEKEVDDADVLECYFIEAMYWSLGATLLETGRIKFDEYIKRLASMSAAYDESILAGPGELPYQQPTIYDFHFDGEKKKWIPWSKLVPKY-IHKPEEKFIDILVPTVDTTRTTWLLEQMVKIKRPVVLVGESGTSKTATTLNLLRNLNTDMLLSINFSSRTTSMDIQRNLEANVEKRTKDN---YGPP-MGKRLLVFMDDMNMPKVDEYGTQQPIALLKLLLEKGGMYDRGKELNCKYLRDLGFIAAMGK-AGGGRNEVDTRFISLFSVFNVLFPSEESLSLIYSSILKGHTALFNEEVQAICDKLTFCTLELY----KMIVRDLPPTPSKFHYIFNLRDLSRVYNGL-VLTTPERFQTVAQMVRVWRNENLRVFHDRLVNEEDK-LVQGHIKHLIEEHF-QASLEHATRDPILFGDYRTAMSEGEPRVYEDIQDYEAAKALFQEILEEYNESKTKMNLVLFDDALEHLTRIHRIIRMDRGHALLVGVGGSGKQSLARLAAYAAGYEVFEIVLSRGYGENSFREDLRNLYIKLGLENKKMIFLFTDAHVAEEGFLELINNMLTSGMVPALFPDDEKESVLSQIRDEATKHGVG-PAKESIWQFFVNKSANNLHIVLGMSPVGDTLRTRCRNFPGLVNNTGIDWFLPWPPQALYAVANSFLG------------------DNSLIPSQ--HSEPVTGHVVMVHDSVGKFSKKFQQKLRRSNYVTPKNYLDFINTYSRLLEEKNQYNLAQCKRLEGGLDKLKEATVQLAELNVKLAEQKVVLAEKSSACEALLDEISTNTTIAEEKRKLAEEKAAEIEEQNKVIAVEKQEAESALAEALPILEAAKLELQKLDKSDVTEIRSFAKPPRAVQVVCECILVMRGYKEISWKSAKGMMSDPSFLKSLMEIDFDAITQHQVKAVRG-FLKTLNTTFEEMEAISKAGLGMLKFVEAVMGYCDVAKEIKPKREKVAKLERNYYMSKRDLEKIQAELSTIQNELKALGEKYEAAITEKQKLQEEAEVMERRLIAADKLISGLGSENKRWTNDLEELKVRRVKLLGDCLLCSAFLSYEGAFNWDFRKEMVYTEW-----QQDILAREIPLSQPFRIESLLTDDVEISRWGSEGLPPDELSIQNGILTTRASRFPLCIDPQQQALNWIKRKEEKNNLKISSFNDPDFLKQLEMAIKYGFPFLFQDVDEYIDPVIDNVLEKNIKGAQGRQFIILGDKEVDYDPNFKLYLNTKLSNPKYSPSVFGKAMVINYTVTLKGLEDQLLSVIVGFERRELEEQRENLIQETSENKKLLKDLEDSLLRELATSTGNMLDNVELVHTLEETKAKATEVSEKLKLAEKTAVDIDKLRDGYRPAAKRGAILFFVLSEMALVNSMYQYSLSSFLAVFDHSLRKSLPDGILMK----RLKNIMDTLTYNVYNYGCTGLFEKHKLLFSFNMTVKIEQADGRVP----QEELDFFLK---GNISLEKSKRKKPCSWIPDQGWEDII-RLSELFPSMFGSLPSDVERCEAEWKAWYDLDTLEQYPYPL-----GYND-KLSDFQK----LLLLRCFRVDRVYRAVSDYVTVTMGEKYVQP--PVISFEAIFEQSVPTS-PIVFILSPGSDPASDLMKLAERSGFGGNRLKFLAMGQGQE-KVALQLLETAVFRGQWLMLQNCHLLVKWLKDLEKALEMIKKPHPDFRLWLTTDPTKEFPIGILQKSLKVVTEPPNGLKLNMRATYFKISHEALDSCQHSAFKSLVYVLAFFHAVVQERRKFGKIGWNVPYDFNESDFQVCMEILNTYLTKAFQQHDT----KIPWGSLKYLIGEVMYGGRAIDSFDRRILTTYMDEYLGDFIFDTFQLFHFYKNEEVDYRIPEGTTKDAFVEAIESLPLANTPEVFGLHSNAEIGYYTQAARDMWTHLLELQPQ---TGESSTGISRDEYIGQVAKDIENKLPQIFDLDQIRKNLGLEISPTTVVLLQ----------------ELERFNKLIIRMSRSLVELQRALAGEVGMSSELDEVARALFNGQIPNIWRRLAPDTLKSLGNWMIHFRRRFNQYTSWVNESEPN--------VMWLSGLHIPESYLTALVQATCRKNGWPLDRSTLYTQVTSFRTPEEVTERPGQGCFISGLYLEGAD 4326
BLAST of Cytoplasmic dynein 1 heavy chain 1 vs. Ensembl Mouse
Match: Dync1h1 (dynein cytoplasmic 1 heavy chain 1 [Source:MGI Symbol;Acc:MGI:103147]) HSP 1 Score: 6138.53 bits (15924), Expect = 0.000e+0 Identity = 2957/4618 (64.03%), Postives = 3667/4618 (79.41%), Query Frame = 3 Query: 261 ECLTKFINDNQVTTLTIQQ-TKRXXXXXXXXXXXXKISNEVNFESN---KSQTSIFIKNNQVIEADKTISSQLQVLSYCDGPPFETMHSLVCYGLLPYFXXXXXXXXXXXXXXXXXMVPSVEKKIAELEIGLLHLQQNIEIPEITLTPHPYVAHIIQEKLLQNKEARVSDFEDKFEDTQFLNQLQAGVNRWIKEIQKVTKLNRDPSTGTALQEISFWLNLEHSLDKIQEKRESLEVALTLAILKQAKRFHATTSFDTDTALSSAKIQVKDYNQLMKDFPINDLLSASQLDKISEALQQIFSHLKKVRATKYPVNRIIKLMEALSRDLTTQLMKVISNMHLMSMPYDEFEKIFTACQQVFSTWEDEYDKMQNLLRDIAKKKREEFTKFAWKMNATHKKLQTRLENIKKFRYQHEQLRQVIVRVLKP-VTKVVPSVEAGVPKDQITDKGDKSSTFLPESADTSSIDEVNAAYEIVKVIDCLDFAKEENDEWDAAIKRYEERIDRVESRIASHLRDLLGQSKNANEMFRYFSRFNALFVRPHIRGAIGEYQTQLIQRVKDDIEALHNKFKVQYASSTACKMSKVRDLPPVSGSIIWVRQILRQLNAYMKRVEDVLGKDWAQHIEGQKLKADGESFKLKLNTSELFEEWSKKVAEKSLSVAGSIFNVESTRTVVTVRDREPQKITVLKLKVNFLPDVITLAKEVRNMRALGFRTPLSIVNKAHSANQLYPFAISLIESVRTYESTCSKIEEHKMQNISLLTAGLRKDVQLCIHEGVQITWESYRLDQYVQKLAELVFSFQEKVDDLVIVIKEIDFNVKALETCSYNKQTFEEILIRIQEAVDNMSLHQFSNLAQWVSNLDSLVEQRLIVRLEAGLLEWIKVLKGXXXXXXXXXXXXXXXVNSMAKHRLGGKPQIKKLIHELRITNQQMHLYPSIEVATQDILYQMSSWQNIILNLSRIVHSRYQVGLETE-SDNQKTYKKLLSSLPNSGESLENAYAAVHNILRDANEYVKTWTNYQSLWDLQGDQLFSLIADDNTVWMNVLEEIKSMRKHFDVAETQKEFGPLVIAFGKVQSKVSMKYDNWHKEVLTKFGQNMGKMMTTLYNEVQRARNELEQQSIDSGGTNESVNFITYTQNIKRKMNTWEKQAEACRAGQNILCRDRFQFPNDWLDSENIQGEWSAFKEIMRRKQETISSQVASLQMKITEEDKIVESKTTEVLGNWEKDKPIAGDLTPEEAVNIIQILEGKFNRLKEERENVQKAKEALELTEIGVKPISEEKVTNALSELHDLKNVWNELKSIWEKIRDMKETPWLSVQPRKLRQDIENLTAQLKELPNSFKQYASFEHVRTLLKMYMKVNASIVELKSEAIKERHWRMLMRKLNVSWSLNELQLGKVWDIDLVKNEEIIREVLAIAQGEKALEEYLRQITEVWKNYVLELTNYQSKSKIIKGWDDLFNKVKEHINNVTSMKASPYFKQFEEEATAWEDRLNKINALFDVWIDVQRRWIYLDGIFAGSADIKVLLPVESQRFQSVSTEFLGLMKKVQKSPLVTDVLNIANVQRQLERLADLLGKIQKSLGEYLERQRSSFPRFYFVGDEDLLEIIGNSXXXXXXXXXXXXMFAGVHSIILSEDEKVILGMMSKEGEELRFISPVSIIEHPRINDWLTAMEKEMRVSLAKYLNVAVKEISGWRTESNIDKDKFMVWLDKYQAQIVVLAAQITWSEAVEASLASGVS------LESTMTVVHSTLNMLADTVLYEQPPVRRRKLEHLIIEYVHQRDVLRALHNDGVSSNKNFDWMSQMRFYFDPKQTDPLHQLSIHVANAKFHYGFEYLGVCDRLVQTPLTDRCYLTMTQALEARLGGSPFGPAGTGKTESVKSLGNQLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLSAVSQQIQGIQEALRELMVSKKDS----INVELLGKQVHVNPDMAIFITMNPGYAGRSNLPDNLKKLFRSLAMTQPDRQLIAQVMLYSQGFRTAEVLAGKVVPFFKLCDEQLSPQSHYDFGLRALKSVLVSAGNVKRDRIKQEKEKIVARGEEINETAIAEQLPEQEILIQSVMETMVPKLIADDIPLLYSLLTDVFPGVEYRQAEMKRLREELRKVSENKFLVYSDEPNTAGYLWVEKVLQLYQITTIHHGLMMVGPSGSGKTMACRVLLQALENIDGIEGVAHIIDPKSISKDSLYGYMDPNTREWTDGLFTHILRRIIDSVRGESNKRQWIVFDGDVDPEWVENLNSVLDDNKLLTLPNGERLAIPPNVRIMFEVQDLKYATLATVSRCGMVWFSEEVLTTGMILTHFLNELKKVQVMEGEEDFSVNQGDTGADADSKISSSPIIQLQTQVSSILAPFFTEDGLIAKCLDYSTTLEHIMDFTRLRALTSLFSMIKQSIRNMIEYNQSHSDFPLNNEQIENYVAKSLISSVVWSMSGDSKLKVREQLSQYIKNISTVDLPTVGGIKNIIDFEVNIQGTWVAWSNKVPQIEVETHKITATDVVVPTMDTVRHEALLYTWLAEHRPVLLCGPPGSGKTMTLFSALRCLPDMEVVGLNFSSATTPELMLKTFDQYCEYRKTPNGIVLAPQQLNKWLIFFCDEINLPDMDKYGTQRVISFLRQMVEHHGFYRITDMQWVSFERIQFVGACNPPTDPGRKPLSHRFLRHVPVVYVDYPGETSLKQIYSTFNRAMLRMLPSLRGYADTLTNAMVEFFLKTQERFTHDMQPHYIYSPREMTRWVRGIHEALKPLESLSVEGLVRIWAHEALRLFQDRLVEEDERHWTDDNINEVALKHFPNINKEEALKRPILYSNWLSKDYSAVTQEELRDYVKARLKVFYEEELDVPLVLFNQVLDHVLRIDRVFRQPQGHLLLIGVSGAGKTTLSRFVSWINGLSVFQVKVHNKYTAEDFDEDLRNVLRRSGCKGEKITFIMDESNVMDSSFLERMNTLLANGEVPGLFEGDELTTLMTQCKEGAIREGLMIDSQEELYKWFTQQICRNLHVVFTMNPSADGLKDKASTSPALFNRCVLNWFGDWSLEAYFQVGKEFTNRLDLERTDYKVPDTLPCIAEGLLPQNPIYRDVVVNALVFVHQTMHQANVRVQKRGGRTAAITPRHYLDLIAHYMKLSAEKRADLEEQQLHLNNGLKKIEQTVDQVEVMQRSLTKKRQELENMNEAANAKLKQMVQDQQEAEQKKTTGQALKEELAKQEQFVNEKQKTVKQELDQVEPTVNEAKQAVQNIRKKDIQEIKAMKNPPNAVKMAVESICLLLGEKTTDWQSILKVIIKDTFVTSILNFNTDDVSDNTRETMKKKYLSNPDYNFEKVNKASNACGPMVKWVLAQISYADILKRVEPLRNELTELSDAAEQNRKKSQETEDLIAQLEKSIAKYTEEYATLISQAQTIKSDLASVESKVGRSVALLGSLSSERTRWDSGSETFKAQMATINGDCLLSSAFMAYGGYFDQHMRTSLFNTWCHHLSEADILFRSDLARVEYLSNPDDRLRWQANSLPADDLCVENAIILRRYNRYPLIIDPSGQATTFLLNEYKEKKITKTSFLDDSFRKTLESALRFGTPLLVQDVESYDPILNPVLNREVRRTGGRTLITLGDQDIDLSPTFTIFLSTRDPSVEFAPDICSRVTFVNFTVTRSSLQNQCLNAVLKIERPDIDQKRSDLLKAQGEFQLKLRHLEKDLLQSLNEAQGNLLENDKIIARLETLKREAADVAKKVEETDVVMQEVESVSTEYVPLAQSCSNIYFTLEAMNQIHFLYQYSLQLMLDIFSSVLINNPELTNVKAASDRLKIITKNLFQVTYNRLARGMLHEDQITFATILARIFLKGSTPIGFLENEFQHFLRSQEATITSSDSNKQDNLGLTLHQDQIDSVKRLKKLKVFAKIEEKVKSTKDIKNWTLTVTPESNVPELWVDDNNYNDEKLSKIAKGMYNLLIIQAIRPDRLLASTQKFIASVLGDTFTESVRGTLDLASIVEVEVTACVPILLCAVQGYDPSGRVEDLASEQGKQLTGIAIGSAEGFSQAEKAINSAAKTGKWVMLKNVHLATSWLVSLEKKIHSLQAHPNFRLFLTMEITPKLPVNLLRAGRVLVFEPPPGIKANLLRTLSSINNQRMSKEPVERSRLYFLLAWLNAIVQERLRYVPLGYSKKYEFGESDFKCALDTIDTWVDGAAMGRTNLPPEKIPWVALQTLLGSCIYGGKIDNAFDQRLLNSFLGYLFTEKCFDHNFALVSDADDGSNIAFPESTKHTDILQWVHKLPDLQTPSWLGLPNSAEKVLLTNLGQSLIGNILKMQQSLEDDEELVVGQSKTK-RTIEVGDGRPAWMRQLYQSTQTWLQILPKSVTPLQRTIENIKDPMYRCFEREVNSGCNLLASVRKDLEDVAEVCKGAKKPTNHHRSMMADLAKGIIPKMWIRYAIPPGLTVIQWIQDFADRIKQLLHISDTAAKSGVIALRSIQVWLGGLFMAEAYITATRQSVAQNNKWALEELFLDVELGEGK---VDSNTCVITGLRLMGSEIVDPRTLKLSTLIYKDIDICRLKWIRVEKSQQLEGSSAKDKVCLPIYLNAARSTVLFTLYF--STTDSSYDFYKRGVAI 14048 E + KF++D QV T+ +++ T +E+ E IS +N + + KS + FIK VI+ADK +SSQL+VL+ + P+ET+HS + + P+FKSYI++ GK M PSVEKKIAELE+GLLHLQQNIEIPEI+L HP + ++ ++ + ++ +V+DF DK ED FLNQLQ+GVNRWI+EIQKVTKL+RDP++GTALQEISFWLNLE +L +IQEKRES EV LTL ILK KRFHAT SFDTDT L A V DYN LMKDFP+NDLLSA++LDKI +AL IF+HL+K+R TKYP+ R ++L+EA+SRDL++QL+KV+ LM + Y+EFEK+ AC +VF TW+DEY+K+Q LLRDI K+KREE K W++N H+KLQ RL+ ++KFR QHEQLR VIVRVL+P VT V + P+ Q K + L ++AD ++I+EVN AYE VK +D LD +KE + W+AA+KRY+ERIDRVE+RI + LRD LG +KNANEMFR FSRFNALFVRPHIRGAI EYQTQLIQRVKDDIE+LH+KFKVQY S ACKMS VRDLPPVSGSIIW +QI RQL AYMKRVEDVLGK W H+EGQKLK DG+SF++KLNT E+F++W++KV +++L V+G IF +ES R VR R VLKLKVNFLP++ITL+KEVRN++ LGFR PL+IVNKAH ANQLYPFAISLIESVRTYE TC K+EE ISLL AGL+K+VQ I EG+ + WESY+LD YVQ+LAE VF+FQEKVDDL+I+ ++ID V++LETC Y+ +TF EIL R+Q+AVD+++LH +SNL WV+ LD +E+ L VRL+AGL W +VL G+ + E D DTD H+ GG+P+IK ++HELRITNQ ++L P IE + +M +W+ ++L+L RI RYQVG+ E ++ +K Y+ L+ +P+ +LE +Y+AV I+ + +YVK W YQ LWD+Q + +++ + +D W +L +I+ R FD AET+KEFGP+VI +GKVQSKV++KYD+WHKEVL+KFGQ +G MT ++++ ++R ELEQ S+D+ T+++V FITY Q++KRK+ +EKQ E R GQ +L + RFQFP WL +NI+GEW AF +IMRRK I QVA+LQMKI +ED+ VES+TT++L +WEK KP+ G+L PEEA+ + I EGKF RLK++RE KAKEALELT+ G+ SEE+V AL EL DLK VW+EL +WE+I MKE PW+SVQPRKLRQ+++ L QLK P +QYAS+E V+ LLK YMK+N ++ELKSEA+K+RHW+ LM++L+V+W ++EL LG++WD+DL KNE ++++VL +AQGE ALEE+L+QI EVW Y L+L NYQ+K ++I+GWDDLFNKVKEHIN+V++MK SPY+K FEE+A +WED+LN+I ALFDVWIDVQRRW+YL+GIF GSADIK LLPVE+QRFQS+STEFL LMKKV KSPLV DVLNI VQR LERLADLLGKIQK+LGEYLER+RSSFPRFYFVGDEDLLEIIGNSK++ KLQKHFKKMFAGV SIIL+ED V+LG+ S+EGEE+ F +PVSI EHP+IN+WLT +EKEMRV+LAK L +V E+ + ++ID + ++ W+DKYQAQ+VVL+AQI WSE VE +L++ L+S ++ V TLN+LAD+VL EQPP+RRRKLEHLI E VHQRDV R+L + + K+F+W+SQMRFYFDPKQTD L QLSI +ANAKF+YGFEYLGV D+LVQTPLTDRCYLTMTQALEARLGGSPFGPAGTGKTESVK+LG+QLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLSAVSQQ+Q IQEALRE D I ELL KQV V+PDMAIFITMNPGYAGRSNLPDNLKKLFRSLAMT+PDRQLIAQVMLYSQGFRTAEVLA K+VPFFKLCDEQLS QSHYDFGLRALKSVLVSAGNVKR+RI++ K + RGE ++E IAE LPEQEILIQSV ETMVPKL+A+DIPLL+SLL+DVFPGV+Y + EM LREEL+KV + +L Y D G +WVEKVLQLYQIT I+HGLMMVGPSGSGK+MA RVLL+ALE ++G+EGVAHIIDPK+ISKD LYG +DPNTREWTDGLFTH+LR+IID+VRGE KRQWIVFDGDVDPEWVENLNSVLDDNKLLTLPNGERL++PPNVRIMFEVQDLKYATLATVSRCGMVWFSE+VL+T MI +FL L+ + + EGE++ + G + + + ++SP++Q+Q ++I+ P+FT +GL+ K L+++ LEHIMD TRLR L SLFSM+ Q+ RN+ +YN +H DFP+ EQ+E Y+ + L+ +++WS+SGDS+LK+R +L +YI+ I+TV LPT + IID+EV+I G W W KVPQIEVETHK+ A DVVVPT+DTVRHEALLYTWLAEH+P++LCGPPGSGKTMTLFSALR LPDMEVVGLNFSSATTPEL+LKTFD YCEYR+TPNG+VLAP QL KWL+ FCDEINLPDMDKYGTQRVISF+RQMVEH GFYR +D WV ERIQFVGACNPPTDPGRKPLSHRFLRHVPVVYVDYPG SL QIY TFNRAMLR++PSLR YA+ LT AMVEF+ +QERFT D QPHYIYSPREMTRWVRGI EAL+PLE+L VEGL+RIWAHEALRLFQDRLVE++ER WTD+NI+ VALKHFPNI+KE+A+ RPILYSNWLSKDY V QEELRDYVKARLKVFYEEELDVPLVLFN+VLDHVLRIDR+FRQPQGHLLLIGVSGAGKTTLSRFV+W+NGLSV+Q+KVH KYT EDFDEDLR VLRRSGCK EKI FIMDESNV+DS FLERMNTLLANGEVPGLFEGDE TLMTQCKEGA +EGLM+DS EELYKWFT Q+ RNLHVVFTMNPS++GLKD+A+TSPALFNRCVLNWFGDWS EA +QVGKEFT+++DLE+ +Y VPD +P + + L PQ P +R+ +VN+ VFVHQT+HQAN R+ KRGGRT AITPRHYLD I HY L EKR++LEEQQ+HLN GL+KI++TVDQVE ++R L K QELE N AAN KLK+MV+DQQEAE+KK Q ++E+L KQ++ + +KQ +VK++LD+VEP V EA+ AV++I+K+ + E+++M NPP AVK+A+ESICLLLGE TTDW+ I +I+++ F+ +I+NF+ +++SD RE MKK Y+SNP YN+E VN+AS ACGPMVKW +AQ++YAD+LKRVEPLRNEL +L D A+ N++K+ E E +I LE SIA+Y EEYA LIS+AQ IK+DLA+VE+KV RS ALL SLS+ER RW+ SETFK QM+TI GDCLLS+AF+AY GYFDQ MR +LF TW HHL +A+I FR+D+AR EYLSN D+RLRWQA+SLPADDLC ENAI+L+R+NRYPLIIDPSGQAT F++NEYK++KIT+TSFLDD+FRK LESALRFG PLLVQDVESYDP+LNPVLNREVRRTGGR LITLGDQDIDLSP+F IFLSTRDP+VEF PD+CSRVTFVNFTVTRSSLQ+QCLN VLK ERPD+D+KRSDLLK QGEFQL+LR LEK LLQ+LNE +G +L++D II LE LKREAA+V +KVEETD+VMQEVE+VS +Y+PL+ +CS+IYFT+E++ Q+HFLYQYSLQ LDI+ +VL NP L + RL IITK+LFQV +NR+ARGMLH+D ITFA +LARI LKG+ + EFQHFLR +E +++ + K GLT+ +Q ++V RL L F + KV++ + W + +PE VP LW ++ + I + ++ LL+IQA RPDRLLA F+++ LG++F + LDL IV EV P+L+C+V GYD SG VEDLA+EQ Q+T IAIGSAEGF+QA+KAIN+A K+G+WVMLKNVHLA WL+ LEKK+HSLQ H FRLFLTMEI PK+PVNLLRAGR+ VFEPPPG+KAN+LRT SSI R+ K P ER+RLYFLLAW +AI+QERLRY PLG+SKKYEFGESD + A DT+DTW+D A GR N+ P+KIPW AL+TL+ IYGG++DN FDQRLLN+FL LFT + FD F L D +I P+ + + +QWV LPD QTPSWLGLPN+AE+VLLT G +I +LKMQ LED+++L +++ K RT DGRPAWMR L+ + WL ++P++++PL+RT+ENIKDP++R FEREV G LL VR+DL DV +VC+G KK TN+ R+++ +L KGI+P+ W Y +P G+TVIQW+ DF++RIKQL +IS AA G L++I V LGGLF+ EAYITATRQ VAQ N W+LEEL L+V + + +D+ + +TGL+L G+ + + L LS I + + +L+W++ Q V LP+YLN R+ ++FT+ F +T + FY+RGVA+ Sbjct: 61 EQMRKFLSDPQVHTVLVERSTLKEDVGDEGEEEKEFISYNINIDIHYGVKSNSLAFIKRAPVIDADKPVSSQLRVLTLSEDSPYETLHSFISNAVAPFFKSYIRESGKADRDGDK-MAPSVEKKIAELEMGLLHLQQNIEIPEISLPIHPIITNVAKQCYERGEKPKVTDFGDKVEDPTFLNQLQSGVNRWIREIQKVTKLDRDPASGTALQEISFWLNLERALYRIQEKRESPEVLLTLDILKHGKRFHATVSFDTDTGLKQALETVNDYNPLMKDFPLNDLLSATELDKIRQALVAIFTHLRKIRNTKYPIQRALRLVEAISRDLSSQLLKVLGTRKLMHVAYEEFEKVMVACFEVFQTWDDEYEKLQVLLRDIVKRKREENLKMVWRINPAHRKLQARLDQMRKFRRQHEQLRAVIVRVLRPQVTAVAQQNQGEAPEPQDM----KVAEVLFDAADANAIEEVNLAYENVKEVDGLDVSKEGTEAWEAAMKRYDERIDRVETRITARLRDQLGTAKNANEMFRIFSRFNALFVRPHIRGAIREYQTQLIQRVKDDIESLHDKFKVQYPQSQACKMSHVRDLPPVSGSIIWAKQIDRQLTAYMKRVEDVLGKGWENHVEGQKLKQDGDSFRMKLNTQEIFDDWARKVQQRNLGVSGRIFTIESAR----VRGRTG---NVLKLKVNFLPEIITLSKEVRNLKWLGFRVPLAIVNKAHQANQLYPFAISLIESVRTYERTCEKVEERN--TISLLVAGLKKEVQALIAEGIALVWESYKLDPYVQRLAETVFNFQEKVDDLLIIEEKIDLEVRSLETCMYDHKTFSEILNRVQKAVDDLNLHSYSNLPIWVNKLDMEIERILGVRLQAGLRAWTQVLLGQAEDKAEVDMDTDA---PQVSHKPGGEPKIKNVVHELRITNQVIYLNPPIEECRYKLYQEMFAWKMVVLSLPRIQSQRYQVGVHYELTEEEKFYRNALTRMPDGPVALEESYSAVMGIVTEVEQYVKVWLQYQCLWDMQAENIYNRLGEDLNKWQALLVQIRKARGTFDNAETKKEFGPVVIDYGKVQSKVNLKYDSWHKEVLSKFGQMLGSNMTEFHSQISKSRQELEQHSVDTASTSDAVTFITYVQSLKRKIKQFEKQVELYRNGQRLLEKQRFQFPPSWLYIDNIEGEWGAFNDIMRRKDSAIQQQVANLQMKIVQEDRAVESRTTDLLTDWEKTKPVTGNLRPEEALQALTIYEGKFGRLKDDREKCAKAKEALELTDTGLLSGSEERVQVALEELQDLKGVWSELSKVWEQIDQMKEQPWVSVQPRKLRQNLDGLLNQLKNFPARLRQYASYEFVQRLLKGYMKINMLVIELKSEALKDRHWKQLMKRLHVNWVVSELTLGQIWDVDLQKNEAVVKDVLLVAQGEMALEEFLKQIREVWNTYELDLVNYQNKCRLIRGWDDLFNKVKEHINSVSAMKLSPYYKVFEEDALSWEDKLNRIMALFDVWIDVQRRWVYLEGIFTGSADIKHLLPVETQRFQSISTEFLALMKKVSKSPLVMDVLNIQGVQRSLERLADLLGKIQKALGEYLERERSSFPRFYFVGDEDLLEIIGNSKNVAKLQKHFKKMFAGVSSIILNEDNSVVLGISSREGEEVMFKTPVSITEHPKINEWLTLVEKEMRVTLAKLLAESVTEVEIFGKATSIDPNTYITWIDKYQAQLVVLSAQIAWSENVENALSNVGGGGDVGPLQSVLSNVEVTLNVLADSVLMEQPPLRRRKLEHLITELVHQRDVTRSLIKSKIDNAKSFEWLSQMRFYFDPKQTDVLQQLSIQMANAKFNYGFEYLGVQDKLVQTPLTDRCYLTMTQALEARLGGSPFGPAGTGKTESVKALGHQLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLSAVSQQVQCIQEALREHSNPNYDKTSAPITCELLNKQVKVSPDMAIFITMNPGYAGRSNLPDNLKKLFRSLAMTKPDRQLIAQVMLYSQGFRTAEVLANKIVPFFKLCDEQLSSQSHYDFGLRALKSVLVSAGNVKRERIQKIKREKEERGEAVDEGEIAENLPEQEILIQSVCETMVPKLVAEDIPLLFSLLSDVFPGVQYHRGEMTALREELKKVCQEMYLTYGDGEEVGG-MWVEKVLQLYQITQINHGLMMVGPSGSGKSMAWRVLLKALERLEGVEGVAHIIDPKAISKDHLYGTLDPNTREWTDGLFTHVLRKIIDNVRGELQKRQWIVFDGDVDPEWVENLNSVLDDNKLLTLPNGERLSLPPNVRIMFEVQDLKYATLATVSRCGMVWFSEDVLSTDMIFNNFLARLRSIPLDEGEDE--AQRRRKGKEDEGEEAASPMLQIQRDAATIMQPYFTSNGLVTKALEHAFKLEHIMDLTRLRCLGSLFSMLHQACRNVAQYNANHPDFPMQIEQLERYIQRYLVYAILWSLSGDSRLKMRAELGEYIRRITTVPLPTAPNVP-IIDYEVSISGEWSPWQAKVPQIEVETHKVAAPDVVVPTLDTVRHEALLYTWLAEHKPLVLCGPPGSGKTMTLFSALRALPDMEVVGLNFSSATTPELLLKTFDHYCEYRRTPNGVVLAPVQLGKWLVLFCDEINLPDMDKYGTQRVISFIRQMVEHGGFYRTSDQTWVKLERIQFVGACNPPTDPGRKPLSHRFLRHVPVVYVDYPGPASLTQIYGTFNRAMLRLIPSLRTYAEPLTAAMVEFYTMSQERFTQDTQPHYIYSPREMTRWVRGIFEALRPLETLPVEGLIRIWAHEALRLFQDRLVEDEERRWTDENIDMVALKHFPNIDKEKAMSRPILYSNWLSKDYIPVDQEELRDYVKARLKVFYEEELDVPLVLFNEVLDHVLRIDRIFRQPQGHLLLIGVSGAGKTTLSRFVAWMNGLSVYQIKVHRKYTGEDFDEDLRTVLRRSGCKNEKIAFIMDESNVLDSGFLERMNTLLANGEVPGLFEGDEYATLMTQCKEGAQKEGLMLDSHEELYKWFTSQVIRNLHVVFTMNPSSEGLKDRAATSPALFNRCVLNWFGDWSTEALYQVGKEFTSKMDLEKPNYIVPDYMPVVYDKL-PQPPTHREAIVNSCVFVHQTLHQANARLAKRGGRTMAITPRHYLDFINHYANLFHEKRSELEEQQMHLNVGLRKIKETVDQVEELRRDLRIKSQELEVKNAAANDKLKKMVKDQQEAEKKKVMSQEIQEQLHKQQEVIADKQMSVKEDLDKVEPAVIEAQNAVKSIKKQHLVEVRSMANPPAAVKLALESICLLLGESTTDWKQIRSIIMRENFIPTIVNFSAEEISDAIREKMKKNYMSNPSYNYEIVNRASLACGPMVKWAIAQLNYADMLKRVEPLRNELQKLEDDAKDNQQKANEVEQMIRDLEASIARYKEEYAVLISEAQAIKADLAAVEAKVNRSTALLKSLSAERERWEKTSETFKNQMSTIAGDCLLSAAFIAYAGYFDQQMRQNLFTTWSHHLQQANIQFRTDIARTEYLSNADERLRWQASSLPADDLCTENAIMLKRFNRYPLIIDPSGQATEFIMNEYKDRKITRTSFLDDAFRKNLESALRFGNPLLVQDVESYDPVLNPVLNREVRRTGGRVLITLGDQDIDLSPSFVIFLSTRDPTVEFPPDLCSRVTFVNFTVTRSSLQSQCLNEVLKAERPDVDEKRSDLLKLQGEFQLRLRQLEKSLLQALNEVKGRILDDDTIITTLENLKREAAEVTRKVEETDIVMQEVETVSQQYLPLSTACSSIYFTMESLKQVHFLYQYSLQFFLDIYHNVLYENPNLKGATDHTQRLSIITKDLFQVAFNRVARGMLHQDHITFAMLLARIKLKGTVGEPTYDAEFQHFLRGKEIVLSAGSTPKIQ--GLTV--EQAEAVVRLSCLPAFKDLIAKVQADEQFGIWLDSSSPEQTVPYLWSEET-----PTTPIGQAIHRLLLIQAFRPDRLLAMAHMFVSTNLGESFMSIMEQPLDLTHIVGTEVKPNTPVLMCSVPGYDASGHVEDLAAEQNTQITSIAIGSAEGFNQADKAINTAVKSGRWVMLKNVHLAPGWLMQLEKKLHSLQPHACFRLFLTMEINPKVPVNLLRAGRIFVFEPPPGVKANMLRTFSSIPVSRICKSPNERARLYFLLAWFHAIIQERLRYAPLGWSKKYEFGESDLRSACDTVDTWLDDTAKGRQNISPDKIPWSALKTLMAQSIYGGRVDNEFDQRLLNTFLERLFTTRSFDSEFKLACKVDGHKDIQMPDGIRREEFVQWVELLPDAQTPSWLGLPNNAERVLLTTQGVDMISKMLKMQM-LEDEDDLAYAETEKKARTDSTSDGRPAWMRTLHTTASNWLHLIPQTLSPLKRTVENIKDPLFRFFEREVKMGAKLLQDVRQDLADVVQVCEGKKKQTNYLRTLINELVKGILPRSWSHYTVPAGMTVIQWVSDFSERIKQLQNISQAAASGGAKELKNIHVCLGGLFVPEAYITATRQYVAQANSWSLEELCLEVNVTASQSATLDACSFGVTGLKLQGATCSNNK-LSLSNAISTVLPLTQLRWVK-----QTSAEKKASVVTLPVYLNFTRADLIFTVDFEIATKEDPRSFYERGVAV 4640
BLAST of Cytoplasmic dynein 1 heavy chain 1 vs. Ensembl Mouse
Match: Dnah10 (dynein, axonemal, heavy chain 10 [Source:MGI Symbol;Acc:MGI:1860299]) HSP 1 Score: 1369.76 bits (3544), Expect = 0.000e+0 Identity = 971/3364 (28.86%), Postives = 1699/3364 (50.51%), Query Frame = 3 Query: 3954 LEGKFNR-LKEERENVQKAKEALELTEIGVKPISEE-KVTNALSELHDLKNVWNELKSIWEKIRDMKETPWLSVQPRKLRQDIENLTAQLKELPNSFKQYASFEHVRTLLKMYMKVNASIVELKSEAIKERHWRMLMRKLNVSWSLNE-LQLGKVWDIDLVKNEEIIREVLAIAQGEKALEEYLRQITEVWKNYVLELTNY----QSKSKIIKGWDDLFNKVKEHINNVTSMKASPYFKQFEEEATAWEDRLNKINALFDVWIDVQRRWIYLDGIFAGSADIKVLLPVESQRFQSVSTEFLGLMKKVQKSPLVTDVLNIANVQRQLERLADLLGKIQKSLGEYLERQRSSFPRFYFVGDEDLLEIIGNSXXXXXXXXXXXXMFAGVHSIILSED---EKVILGMMSKEGEELRFISPVSIIEHPRINDWLTAMEKEMRVSLAKYLNVAVKEISGWRTESNIDKDKFMVWLDKYQAQIVVLAAQITWSEAVEASL-----ASGVSLESTMTVVHSTLNMLADTVLYEQPPVRRRKLEHLIIEYVHQRDVLRALHNDGVSSNKNFDWMSQMRFYFDPKQTDPLHQLSIHVANAKFHYGFEYLGVCDRLVQTPLTDRCYLTMTQALEARLGGSPFGPAGTGKTESVKSLGNQLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLSAVSQQIQGIQEALRELMVSKKDSINVELLGKQVHVNPDMAIFITMNPGYAGRSNLPDNLKKLFRSLAMTQPDRQLIAQVMLYSQGFRTAEVLAGKVVPFFKLCDEQLSPQSHYDFGLRALKSVLVSAGNVKRDRIKQEKEKIVARGEEINETAIAEQLPEQEILIQSVMETMVPKLIADDIPLLYSLLTDVFPGVEYRQAEMKRLREELRKV-SENKFLVYSDEPNTAGYLWVEKVLQLYQITTIHHGLMMVGPSGSGKTMACRVLLQALENIDGIEGVAHIIDPKSISKDSLYGYMDPNTREWTDGLFTHILRRIIDSVRGESNKRQWIVFDGDVDPEWVENLNSVLDDNKLLTLPNGERLAIPPNVRIMFEVQDLKYATLATVSRCGMVWFSEEVLTTGMILTHFLNELKKVQVMEGEEDFSVNQGDTGADADSKISSSPIIQLQTQVSSILAPFFTEDGLIAKCLD--YSTTLEHIMDFTRLRALTSLFSMIKQSIRNMIEYNQSHSDFPLNNEQIENYVAKSLISSVVWSMSGDSKLKVREQLSQYIKNISTVD----------LPTVGGIKNIIDFEVNIQ-GTWVAWSNKVPQIEVETHKITATDVVVPTMDTVRHEALLYTWLAEHRPVLLCGPPGSGKTMTLFSALRCLPDME--VVGLNFSSATTPELMLKTFDQYCEYRKTPNGIVLAPQQLNKWLIFFCDEINLPDMDKYGTQRVISFLRQMVEHHGFY-RITDMQWVSFERIQFVGACNPPTDPGRKPLSHRFLRHVPVVYVDYPGETSLKQIY--------STFNRAMLRMLPSLRGYADTLTNAMVEFFLKTQERFTHDMQPHYIYSPREMTRWVRGIHEALKPLESLSVEGLVRIWAHEALRLFQDRLVEEDERHWTDDNINEVALKHFPNINKEEALKRPILYSNW--LSKDYSAVTQEELRDYVKARLKVFYEEELD--------VPLVLFNQVLDHVLRIDRVFRQPQGHLLLIGVSGAGKTTLSRFVSWINGLSVFQVKVHNKYTAEDFDEDLRNVLRRSGCKGEKITFIMDESNVMDSSFLERMNTLLANGEVPGLFEGDELTTLMTQCKEGAIREGLMIDSQEELYKWFTQQICRNLHVVFTMNPSADGLKDKASTSPALFNRCVLNWFGDWSLEAYFQVGKEFTNRLDLERTDYKVPDTLPCIAEGLLPQNPIYRDVVVNALVFVHQTMHQANVRVQKRGGRTAAITPRHYLDLIAHYMKLSAEKRADLEEQQLHLNNGLKKIEQTVDQVEVMQRSLTKKRQELENMNEAANAKLKQMVQDQQEAEQKKTTGQALKEELAKQEQFVNEKQKTVKQELDQVEPTVNEAKQAVQNIRKKDIQEIKAMKNPPNAVKMAVESICLLLGEKTTDWQSILKVIIKDTFVTSILNFNTDDVSDNTRETMKKKYLSNPDYNFEKVNKASNACGPMVKWVLAQISYADILKRVEPLRNELTELSDAAEQNRKKSQETEDLIAQLEKSIAKYTEEYATLISQAQTIKSDLASVESKVGRSVALLGSLSSERTRWDSGSETFKAQMATINGDCLLSSAFMAYGGYFDQHMRTSLFN-TWCHHLSEADILFRSDLARVEYLSNPDDRL-RWQANSLPADDLCVENAIILRRYNRYPLIIDPSGQATTFLLNEYKEKKITKTSFLDDSFRKTLESALRFGTPLLVQDVESY-DPILNPVLNREVRRTGGRTLITLGDQDIDLSPTFTIFLSTRDPSVEFAPDICSRVTFVNFTVTRSSLQNQCLNAVLKIERPDIDQKRSDLLKAQGEFQLKLRHLEKDLLQSLNEAQGNLLENDKIIARLETLKREAADVAKKVEETDVVMQEVESVSTEYVPLAQSCSNIYFTLEAMNQIHFLYQYSLQLMLDIFSSVLINN-PELTNVKAASDRLKIITKNLFQVTYNRLARGMLHEDQITFATILARIF--LKGSTPIGFLENEFQHFLRSQEATITSSDSNKQDNLGLTLHQDQIDSVKRLKKLK-VFAKIEEKVKSTKDI-KNWTLTVTPESNVPELWVDDNNYNDEKLSKIAKGMYNLLIIQAIRPDRLLASTQKFIASVLGDTFTESVRGTLDLASIVEVEVTACVPILLCAVQGYDPSGRVEDLASEQ---GKQLTGIAIGSAEGFSQAEKAINSAAKTGKWVMLKNVHLATSWLVSLEKKIHSL-QAHPNFRLFLTMEITPKLPVNLLRAGRVLVFEPPPGIKANLLRTLSSINNQRMSKEPVERSR-LYFLLAWLNAIVQERLRYVPLGYSKKYEFGESDFKCALDTIDTWVDGAAMGRTNLPPEKIPWVALQTLLGSCIYGGKIDNAFDQRLLNSFLGYLFTEKCFD--HNFALVSDADDGSNIAFPESTKHTDILQWVHKLPDLQTPSWLGLPNSAEKVLLTNLGQSLIGNILKMQQSLEDDEELVVGQSKTKRTIEVGDGRPAWMRQLYQSTQT----WLQILPKSVTPLQRTIENIKDPMYRCFEREVNSGCNLLASVRKDLEDVAEVCKGAKKPTNHHRSMMADLAKGIIPKMWIRYAIPPGLTVIQWIQDFADRIKQLLHISDTAAKSGVIALRSIQVWLGGLFMAEAYITATRQSVAQNNKWALEE--LFLDVELGEGKVDSN-----TCVITGLRLMGSE 13817 L G F + L + +N Q+ A +L ++ + E KV ++ L + ++N LK E + +T W+++ + L++ IE L++LP + + H+ +K + +++LK EA++ERHW+ LM K V + + E L ++ ++L K+ E++ E++ A E A+E+ +++I + W+N + Y Q + I+ DD+ + ++ N+ S+ S + F + WE L+ I + ++W+ VQR+W+YL+ IF G DI+ LP E+++F ++ F +M + K P++ N L+ +++ L K QKSL +YL+ +R++FPRF+F+ D++LL I+GNS L + K M+ + + + EK++ M+S EGE + F + R+ DW+TA+ EMR + A+ R S +D W+ YQ +V+ A+Q+ W+ VE ++++ +HS ++ L + E R+K ++I VH RD++ + + + F+W SQ+RFY+D ++ D +L+I F YG+EY+G+ RLV TPLTDR YLT+TQAL LGG+P GPAGTGKTE+ K L LG +V NC E D++A+G+IF GL Q GAWGCFDEFNR++ +LS +S QIQ I+ AL + + + G+++ ++ M IFITMNPGYAGR+ LP+++K LFR + + PD Q I ++ML+S+GF A+ LA K+ +KL EQLS Q HYDFGLRALKSVLV AG +KR + L E +L++++ + +PK + +D+PL L++D+FPG++ + + + +V EN +++ + V+KV+Q+++ H M+VGP+G GK++ L QA + GI +I++PK++S LYG +DP TR+WTDG+ ++I R I + + +R++I+FDGDVD WVEN+NSV+DDNKLLTL NGER+ + + ++FEV DL+YA+ ATVSRCGMV+ + L +L +++ +K+ + L + L D +I +D L+ ++ T L +T L M+ + IE D L +E + ++L S+ S+ + ++K E + + + ++ TVD LP G + ++ DF + + W+ W+ VP+ V +H+ D++V T+DT R +L + PVL G G+ KT T + L+ L + V+ +NFSS TT + + + E R P + K L+ F D++N+P +D+YGTQ+ I+ L+ ++E Y R ++ S + F+ A GR + RFL V V +P E SL IY STFN ++ + L TL +V+ T +F HYI++ R+++R G+ P +V +VR+W +E LR+F DRL+ E ++ ++I + +HF N + E ++ PIL+ ++ ++ E+++DY A K +EE L+ + LVLF+ L+H+ R+ R+ R +GH LL+GV G+GK +L+R ++ G VF++ + Y+ +F +DL+N+ + G + + + F+ +++V + FLE +N +L +G VP LF +E ++ Q + A++ G M ++E ++++F + NLH+V M+P D L+ + P L N ++WF W +A V K F + +PD E L + +V +V VHQ++ + + + Q++ R+ +TP++YLD I Y KL EK Q L GL K+++ Q++ + L +++ L + A A L+++ + AE+KK + E+ +Q + + ++ + L +V P + AK +Q + K D+ EI++ PP V+ E I ++ G K +W++ ++ F+ S++ + D ++ + + K L + E++ S A M+K+V A + Y D+ + ++P R ++ L +++ + ++ +A ++K + +Y I + Q ++ + +E ++ + L+ L SE RW + + + + GDCLL +AF++Y G F R + N W + + + DI S R+E L D + RW + LP D+L V+N I+ R +R+PL IDP QA ++ + ++ + SF D F K LE ++++GTP L DV+ Y DP+++ VL + ++ + GR I LGD+++D F ++L+T+ + ++P + + +N+TVT L++Q L+ ++ ER +++++R L++ E + L+ LE LL+ L + GN+L+N +++ LE K +A +V++K++ + +++ + Y P A+ + ++F L M ++ +YQYSL L++F L + P+ +K RLK I L YN G+ ++ F+ + +G P + E FL+ I+ S + Q D + +K +F + ++ + + W + E L DDN LLI++ R DR+ + ++ +G+ + + + +I E + T PI+ G DP+ + LA G +L +A+G + A + + +A G+W+ML+N HL WL LEK + + + HP+FRL+LT + T P+ +L+ +V EPP G+K N+ T I+N + + P + L ++LA+ +A+VQER ++ +G++ Y+F ESDF+ ++ ++T++ A R +IPW +L+ L+G +YGG+ ++FD+R+L +++ + FD F + D I P ++ + LP TP GL ++AE T + + G++L++Q + G S+ +V M +++ Q L I P SV LQ E+ L+ + + L ++ G +N + L G IP +W + A T+ W+ F R Q + T + V+ WL GL + E+Y+TA Q+ + N W L+ LF V + + N C ++GL L G++ Sbjct: 1339 LLGSFEKELAKHEKNRQELANAEKLFDLPITMYPELIKVQKEMTGLRMIYELYNSLKLAKE---EWSQTLWINLNVQYLQEGIEGFLKNLRKLPRQVRGLSVAFHLEVKMKAFKDSIPLLLDLKHEALRERHWKELMEKTGVFFEMTETFTLENMFAMELHKHTEVLNEIVTAAVKEVAIEKAVKEILDTWENMKFTVVKYYKGTQERGYILGSVDDIIQCLDDNTVNLQSISGSRFVGPFLQTVHKWEKTLSLIGEVIEIWMLVQRKWMYLESIFIG-GDIRSQLPEEAKKFDNIDRIFKRIMGETLKDPVIKRCCEAPNRLHDLQTISEGLEKCQKSLNDYLDSKRNAFPRFFFISDDELLSILGNSDPLCVQEHMIK-MYDNIAMLRFHDGDSGEKLVSAMISAEGEVMTFRKIIR--ADGRVEDWMTAVLHEMRRTNRLITKEAIFRYCEDR--SRVD------WMLLYQGMVVLAASQVWWTWEVEDVFNKVKQGDKQAMKNYGKKMHSQIDDLVTRITMELSKNDRKKYNTVLIIDVHARDIVDSFIRGSILEAREFEWESQLRFYWD-REPD---ELNIRQCTGTFSYGYEYMGLNGRLVITPLTDRIYLTLTQALSMYLGGAPAGPAGTGKTETTKDLAKALGLLCVVTNCGEGMDYKAVGKIFSGLAQCGAWGCFDEFNRIDASVLSVISSQIQTIRNALIHQLTT------FQFEGQEISLDSRMGIFITMNPGYAGRTELPESVKALFRPVVVIVPDLQQICEIMLFSEGFLGAKTLAKKMTVLYKLAREQLSKQHHYDFGLRALKSVLVMAGELKRG---------------------SADLQEDVVLMRALRDMNLPKFVFEDVPLFLGLISDLFPGLDCPRVRYPDFNDAVEQVLEENGYVLLP--------VQVDKVVQMFETMLTRHTTMVVGPTGGGKSVVINTLCQAQTKL-GIMTKLYILNPKAVSVIELYGILDPTTRDWTDGVLSNIFREI--NRPTDKKERKYILFDGDVDALWVENMNSVMDDNKLLTLANGERIRLQAHCALLFEVGDLQYASPATVSRCGMVYVDPKNLKYQPYWKKWLQQIQ-----------------------NKVEQKYLNDLFEKYVPTLI-----DMIIEGIVDGRQGEKLKMVVPQTDLNMVTQLTRMLDSLLEGEIE------DLDL----LECFFLEALYCSLGSSLLEEGRVKFDECIKR-LSSMPTVDSEGNWARPGELP--GHLPSLYDFHFDAKRNHWIPWNKLVPEY-VHSHEKKFVDILVHTVDTTRTTWILEQMVKIKHPVLFVGESGTSKTATTQNFLKNLNEETNIVLIVNFSSRTTSLDIQRNLEANVEKRTKD---TYGP-PMGKRLLVFMDDMNMPKVDEYGTQQPIALLKLLLEKGYLYDRGKELNCKSIRDLGFIAAMG-KAGGGRNEVDPRFLSLFSVFNVPFPSEESLNLIYYSILKGHTSTFNESIGGVSRKLTFCTLTLYKNIVQDLPPTPSKF------HYIFNLRDLSRVFNGL-VLTNPDRFQTVSQMVRVWRNECLRVFHDRLINEVDKELVQNHIGNLVTEHF-NDDFEMVMRDPILFGDFRLALQEGEPRIYEDIQDYEAA--KALFEEILEEYNEVNTKMNLVLFDDALEHLTRVHRIIRMDRGHALLVGVGGSGKQSLARLAAFTAGCEVFEILLSRGYSENNFRDDLKNLYMKLGLENKMMIFLFTDAHVAEEGFLELINNMLTSGMVPALFAEEEKDNILGQIGQEALKFG-MGPAKESVWQFFVNKSANNLHIVLGMSPVGDTLRTRCRNFPGLVNNTGIDWFMPWPPQALHAVAKSFLG------DNSMIPD------EKL--------EELVEHVVMVHQSVGEFSKQFQQKLRRSNYVTPKNYLDFINTYSKLLDEKTQYNIAQCKRLEGGLDKLKEATIQLDELNLKLAEQKIVLAEKSAACEALLEEIATNTAIAEEKKKLAEEKAIEIEEQNKIIAVEKAEAETALAEVMPILEAAKLELQKLDKSDVTEIRSFAKPPKQVQTVCECILIMKGYKELNWKTAKGMMSDPNFLRSLMEIDFDSITQGQVKNI-KGLLKTLNTTIEEMEAVSKAGLGMLKFVEAVMGYCDVFREIKPKREKVARLERNFFLTKRELERIQNELAAIQKELEALGAKYEAAILEKQKLQEEAEIMERRLIAADKLISGLGSENVRWLNDLDELMHRRVKLLGDCLLCAAFLSYEGAFTWEFRDEMVNQVWQNDILDRDIPL-SQPFRLENLLTDDVEISRWGSQGLPPDELSVQNGILTTRASRFPLCIDPQQQALNWIKRKEEKNNLRVASFNDPDFLKQLEMSIKYGTPFLFHDVDEYIDPVIDSVLEKNIKTSQGRQFIILGDKEVDYDSNFRLYLNTKLANPRYSPSVFGKAMVINYTVTLKGLEDQLLSVLVAYERRELEEQREHLIQETSENKNLLKDLEDSLLRELATSTGNMLDNVELVQTLEETKSKATEVSEKLKLAEKTALDIDRLRDGYRPAARRGAILFFVLSEMALVNSMYQYSLIAFLEVFGLSLKKSLPDSILLK----RLKNIMDTLTFNIYNYGCTGLFERHKLLFSFNMTIKIEQAEGRVP----QEELDFFLK---GNISLEKSKWKKPCTWLSDQGWEDIILLSQKFSDIFGNLPLDIEHHLPMWQEWYDQDSLEQFPFPLGYDDN----------ITAFQKLLILRCFRVDRVYRAVTDYVTLTMGEKYVQP--PMISFEAIFE-QSTPNSPIVFILSPGSDPASDLMKLAERSGFGGTRLKFLAMGQGQE-KVALQLLETAVARGQWLMLQNCHLLVKWLKDLEKSLERITKPHPDFRLWLTTDPTKGFPIGILQKSLKVVTEPPNGLKLNMRATYFKISNDMLEQCPHTAFKPLVYVLAFFHAVVQERRKFGKIGWNVYYDFNESDFQVCMEILNTYLTKAFQQRD----PRIPWGSLKYLIGEVMYGGRAIDSFDRRILTTYMDEYLGDFIFDTFQPFHFFRNKDVDYKI--PVGDIKDKFVEAIEALPLANTPEVFGLHSNAEIGYYTQAARDMWGHLLELQPQTGESSS---GVSRDDYIGQVAKDIENKMPKIFDLDQVRKHLGLSITPTSVVLLQ----------------ELGRFNKLVIRMTRSLAELQRALAGEVGMSNELDDVARSLFLGHIPHIWRKLAPDTLKTLGNWMVYFLRRFSQYT-LWVTEGEPSVM-------WLSGLHIPESYLTALVQATCRRNGWPLDRSTLFTQVTKFQDADEVNERAGQGCFVSGLYLEGAD 4507
BLAST of Cytoplasmic dynein 1 heavy chain 1 vs. Ensembl Mouse
Match: Dnah2 (dynein, axonemal, heavy chain 2 [Source:MGI Symbol;Acc:MGI:107731]) HSP 1 Score: 1369.76 bits (3544), Expect = 0.000e+0 Identity = 986/3614 (27.28%), Postives = 1768/3614 (48.92%), Query Frame = 3 Query: 3126 VGLETESDNQKTYKKLLSSLPNSGESLENAYAAVHNILRDANEYVKTWTNYQSLWDLQGDQLFSLIADDNTVWMNVLEEIKSMRKHFDVAE-TQKEFGPLVIAF-----GKVQSKVSMKYDNWHKEVLTKFGQNMGKMMTTLYNEVQRARNELEQ--QSIDSGGTNESVNFITYTQNIKRKMNTWEKQAEACRAGQNILCRDRFQFPNDWLDS-ENIQGEWSAFKEIMRRKQETISSQVASLQMKITEEDKIVESKTTEVLGNWEKDKPIAGDLTPEEAVNIIQILEGKFNRLKEERENVQKAKEALELTEIGVKPISEEKVTNALSELHDLKNVWNELKSIWEKIRDMKET-------PWLSVQPRKLRQDIENLTAQLKELPNSFK--QYASFEHVRTLLKMYMKVNASIVELKSEAIKERHWRMLMRKLNVSWSLNE--LQLGKVWDIDLVKNEEIIREVLAIAQGEKALEEYLRQITEVWKNYVLELTNYQSKSKI-IKGWDDLFNKVKEHINNVTSMKASPYFKQFEEEATAWEDRLNKINALFDVWIDVQRRWIYLDGIFAGSADIKVLLPVESQRFQSVSTEFLGLMKKVQKSPLVTDVLNIANVQRQLERLADLLGKIQKSLGEYLERQRSSFPRFYFVGDEDLLEIIGNSXXXXXXXXXXXXMFAGVHSIIL-----SEDEKVILGMMSKEGEELRFISPVSIIEHPRINDWLTAMEKEMRVSLAKYLN---VAVKEISGWRTESNIDKDKFMVWLDKYQAQIVVLAAQITWSEAVEASLASGVSLESTMTVVHSTLNMLADTVLYEQPPVRRRKLEHLIIEYVHQRDVLRALHNDGVSSNKNFDWMSQMRFYFDPKQTDPLHQLSIHVANAKFHYGFEYLGVCDRLVQTPLTDRCYLTMTQALEARLGGSPFGPAGTGKTESVKSLGNQLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLSAVSQQIQGIQEALRELMVSKKDSINVELLGKQVHVNPDMAIFITMNPGYAGRSNLPDNLKKLFRSLAMTQPDRQLIAQVMLYSQGFRTAEVLAGKVVPFFKLCDEQLSPQSHYDFGLRALKSVLVSAGNVKRDRIKQEKEKIVARGEEINETAIAEQLPEQEILIQSVMETMVPKLIADDIPLLYSLLTDVFPGVEYRQAEMKRLREELRKVSENKFLVYSDEPNTAGYLWVEKVLQLYQITTIHHGLMMVGPSGSGKTMACRVLLQALENI-DGIEGVAHII-----DPKSISKDSLYGYMDPNTREWTDGLFTHILRRIIDSVRGESNKRQWIVFDGDVDPEWVENLNSVLDDNKLLTLPNGERLAIPPNVRIMFEVQDLKYATLATVSRCGMVWFSEEVLTTGMILTHFLNELKKVQVMEGEEDFS--VNQGDTGADADSKISSSPIIQLQTQVSSILAPFFTEDGLIAKCLDYSTTLEHIMDFTRLRALTSLFSMIKQSIRNMIEYNQSHSDFPLNNEQIENYVAKSLISSVVWSMSGDSKLKVREQLSQYIKNISTVDLPTVGGIKN---IIDFEVNIQ-GTWVAWSNKVPQIEVETHKITATDVVVPTMDTVRHEALLYTWLAEHRPVLLCGPPGSGKTMTLFSALRCLPDME--VVGLNFSSATTPELMLKTFDQYCEYRKTPNGIVLAPQQLNKWLIFFCDEINLPDMDKYGTQRVISFLRQMVEHHGFYRITDMQWVSFERIQFVGACNPPTDPGRKPLSHRFLRHVPVVYVDYPGETSLKQIYSTF-NRAMLRMLPSLRGYADTLTNAMVEFFLKTQERF-THDMQPHYIYSPREMTRWVRGIHEALKPLESLSVEGLVRIWAHEALRLFQDRLVEEDERHW----TDDNIN---EVALKHF-PNINKEEALKRPILYSNWLSKDYSAVTQEELRDYVKARLKVFYEEELD--------VP--LVLFNQVLDHVLRIDRVFRQPQGHLLLIGVSGAGKTTLSRFVSWINGLSVFQVKVHNKYTAEDFDEDLRNVLRRSGCKGEKITFIMDESNVMDSSFLERMNTLLANGEVPGLFEGDELTTLMTQCKEGAIREGLMIDSQEELYKWFTQQICRNLHVVFTMNPSADGLKDKASTSPALFNRCVLNWFGDWSLEAYFQVGKEFTNRLDLERTDYKVPDTLPCIAEGLLPQNPIYRDVVVNALVFVHQTMHQANVRVQKRGGRTAAITPRHYLDLIAHYMKLSAEKRADLEEQQLHLNNGLKKIEQTVDQVEVMQRSLTKKRQELENMNEAANAKLKQMVQDQQEAEQKKTTGQALKEELAKQEQFVNEKQKTVKQELDQVEPTVNEAKQAVQNIRKKDIQEIKAMKNPPNAVKMAVESICLLLGEKTTDWQSILKVIIKDTFVTSILNFNTDDVSDNTRETMKKKYLSNPDYNFEKVNKASNACGPMVKWVLAQISYADILKRVEPLRNELTELSDAAEQNRKKSQETEDLIAQLEKSIAKYTEEYATLISQAQTIKSDLASVESKVGRSVALLGSLSSERTRWDSGSETFKAQMATINGDCLLSSAFMAYGGYFDQHMRTSLFN-TWCHHLSEADILFRSDLARVEYLSNPDDRLRWQANSLPADDLCVENAIILRRYNRYPLIIDPSGQATTFLLNEYKEKKITKTSFLDDSFRKTLESALRFGTPLLVQDVESY-DPILNPVLNREVRRTGGRTLITLGDQDIDLSPTFTIFLSTRDPSVEFAPDICSRVTFVNFTVTRSSLQNQCLNAVLKIERPDIDQKRSDLLKAQGEFQLKLRHLEKDLLQSLNEAQGNLLENDKIIARLETLKREAADVAKKVEETDVVMQEVESVSTEYVPLAQSCSNIYFTLEAMNQIHFLYQYSLQLMLDIFSSVLINNPELTNVKAASDRLKIITKNLFQVTYNRLARGMLHEDQITFATILARIFLKGSTPIGFLENEFQHFLRSQEATITSSDSNKQDNLGLTLHQDQI-DSVKRLKKLKVFAKIEEKVKS-TKDIKNWTLTVTPE-SNVPELWVDDNNYNDEKLSKIAKGMYNLLIIQAIRPDRLLASTQKFIASVLGDTFTESVRGTLDLASIVEVEVTACVPILLCAVQGYDPSGRVEDLASEQG--KQLTGIAIGSAEGFSQAEKAINSAAKTGKWVMLKNVHLATSWLVSLEKKIHSLQA---HPNFRLFLTMEITPKLPVNLLRAGRVLVFEPPPGIKANLLRTLSSINNQRMS--KEPVERSRLYFLLAWLNAIVQERLRYVPLGYSKKYEFGESDFKCALDTIDTWVDGAAMGRTNLPPEKIPWVALQTLLGSCIYGGKIDNAFDQRLLNSFLGYLFTEKCFDHNFALVSDADDGSNIAFPESTKHTDILQWVHKLPDLQTPSWLGLPNSAEKVLLTNLGQSLIGNILKMQQSLEDDEELVVGQSKTKRTIEVGDGRPAWMRQL--YQSTQTWLQILPKSVTPLQRTIENIKDPMYRCFEREVNSGCNLLASVRKDLEDVAEVCKGAKKPTNHHRSMMADLAKGIIPKMWIRYAIPPGLTVIQWIQDFADRIKQLLHISDTAAKSGVIALRSIQVWLGGLFMAEAYITATRQSVAQNNKWALEEL 13736 V +E + D +K ++ S + N+ L+N Y+KTW Y+ +W++ D N + +I ++ +VA QKE L I F ++ + + W + T + + L++ ++ ++ Q+++ G + + ++ + E Q IL + P+ L+ E++ GEW F++I+ ++ + + + + K +L ++E P + A++ I + +++E N++ + +G+ I E+ V+ +L L+ + L+ +WE RD +E+ + ++Q + L +L L +K + E R+ ++ + + I +L++ A++ERHW + ++ + L ++ + + ++ E I E+ A A E A+E L+ I + W + L++ Y+ K ++G +++F ++++ +++MKAS + K FE++ WE L+ I + ++ + VQR+W+YL+ IF G DI+ LP ES F V+ + +M ++ K + + L + +L IQKSL YLE +R FPRFYF+ ++DLLEI+G S++ + +Q H KK F + + + S + +GM S +GE + F+ PV ++E P + WL +E+ MR++L L VA+K+ R DK W+ + Q+V+ A+QI W+ V L + + S LN ++ + + R K+ L+ +H RDVL L+ G+ +FDW+SQ+RFY++ D + I N +F YG+EYLG RLV TPLTDRCY+T+T AL GGSP GPAGTGKTE+VK LG LG +V+V NC E D+++MGR++ GL Q GAWGCFDEFNR+ +LS V+QQI I AL + G ++++ IFITMNPGYAGR+ LP+NLK +FR +AM PD LIA+++L+ +GF ++LA KV + L +QLS Q HYDFGLRAL S+L AG +R + L ++E+L+ S+ + + KL + D+PL +++ D+FP +E + +LR+ + + E + + P T + KVLQLY+ H M+VG +GS KT + ++L +L ++ E +I+ +PK++S LYG D NT EWTDG+ + ++R + E +WI+FDG VD W+E++NSV+DDNK+LTL NGER+A+P V ++FEV++L A+ ATVSRCGMV+ L + +L + K +V + F +N+ I+ + + L P G+I+ C Y+ + + N + P + E V + + S++WS+ R+++ Y++ I G N + ++ VN + TW ++ K+P+ ++VPT+DTVR+ L+ T +A PVLL GP G+GKT S L+ LP + V+ +N S+ TT + + E R + K +I F D++N+P D +G+Q + +R +++ GF+ Q + R F+ A P GR +S R ++ + +P E+ + +I+ T N+ + ++ + +T A ++ + +RF + HY+++ R++++ +G+ A K + R+W HE R+F DRLV+ + D + ++ H PN KRP ++ ++L + E+L D LK E L+ VP LVLF + ++H+ RI RV QP+G++LL+G+ G+G+ +L+R S I + FQ++V Y ++F +D++ + R++G + + +F+ ++ + D SFLE +N +L++GEVP L++ DE + + A R + +S + L+ + +++ NLH+V ++P D ++ PAL N +NWF +W EA +V +++ +DL Q I+R V V +H ++ Q + ++ R +TP +YL+L++ Y KL EKR +L +Q L GL KI++T ++VEVM L ++++ + L +VQ ++EA++++ A E++A +E +++L++ P + EA +A++++ KKDI EIK+ PP V++ ++++ +L G + T W + + + F+ S++NF+ D++SD + + Y + PD+ + + + S A + WV A Y + + VEP R + ++ + E ++ + ++ + + ++Y ++Q + ++ +E K+ R+ L+ L+ E+ RW+ + + + + GDCL+++AF++Y G F + R + N W + E + A +L+NP W LP+D EN II+ R NR+ L+IDP GQA ++ N + + + + LE A++FG P+L+Q+V+ Y DP LNPVLN+ V R GGR LI +GD++++ +P F +L+T+ + + P+ ++ T VNF V L+ Q L V++ ERP++++++ L+ + KL+ LE ++L+ LNEA G+LL++ +++ L+T K A +V +++E ++ ++ Y P AQ S ++F L M +I +YQ+SL + +F + I+ +N DR++ + Y R + ++ F+ + L+ S + +E+ FLR + + DN + D D++ L KL F + + +D W +PE + +P W +N N+ M +LI++++R DR+ FI S LG F E L++ S++E + T P++ G DP+ + LA G + +++G + A + + G WV L N HL+ SW+ +L+K + LQ HP+FRL+L+ P P+++L+A + EPP G+KAN+ R + + + +P + +L F L + ++I+ ER +++ LG++ Y F +SDF+ + + + ++D E+ PW AL+ L+ YGG + + +D+RLL +++ F + F +S D P+ +++ LP + P G +A+ ++L +L +Q + V GQS+ ++ +E+ + ++ Y+ T+ L + P P+ +E+ L+ ++ L D+ + +G + + + +P +W + P + W +D A R++Q +T A A + WL G ++TA QS A+ N +++ L Sbjct: 961 VLVERDEDIRKIQAQISSGMTNNASLLQN--------------YLKTWDMYREIWEINKDSFIRRYQRLNPPVSSFDADIA---RYTEVANNVQKEETVLNIQFVMLDCSHLKFSLVQHCNEWQNKFTTLLKEMAAGRLADLHSYLKDNAEKISHPPQTLEELGVS-----LQLMDTLQHDLPNLETQIPPIHEQFTILEKYEVPVPDTVLEMLESLNGEWLTFQQILLDSEQMLKKHKEKFKTGLIHAADDFKKKAHNLLEDFEFKGPFTSTVGHTAALDQIAQMRAMLMAMRDEENNLR--------SNLGIFKI-EQPVSK---DLQILEKELDALQQVWEITRDWEESWNQWKMGCFQTLQTEAMESMAHGLFRRLTRLAKEYKDRNWEIIETTRSKIEQFKRTMPLISDLRNPALRERHWDQVKEEVQREFDQESESFTLEQIVKLGMDQHVEKIAEISASATKELAIEVGLQNIAKTWDSTQLDIVPYKDKGHHRLRGTEEVFQALEDNQVALSTMKASRFVKAFEKDVDHWERCLSLILEVIEMVLTVQRQWMYLENIFLGE-DIRKQLPNESALFDQVNNNWKAIMDRMNKDNNALRSTHYPGLLETLIEMNAILEDIQKSLDMYLETKRHIFPRFYFLSNDDLLEILGQSRNPEAVQPHLKKCFDNIKLLKIQKVGGSSSKWEAVGMFSGDGEYIDFLHPV-LLEGP-VESWLGDVERAMRMTLRDLLRNCRVALKKFLNKR-------DK---WVKDWAGQVVITASQIQWTADVTKCLMTAKERSDKKILKVSILNKYSEAIRGNLTKIMRLKIVALVTIEIHARDVLEKLYKSGLMDVSSFDWLSQLRFYWEKDVDDCI----IRQTNTQFQYGYEYLGNSGRLVITPLTDRCYMTLTTALHLHRGGSPKGPAGTGKTETVKDLGKALGIYVIVVNCSEGLDYKSMGRMYSGLAQSGAWGCFDEFNRINIEVLSVVAQQILSILSAL------TANLTRFYFEGFEINLVWSCGIFITMNPGYAGRTELPENLKSMFRPIAMVVPDSTLIAEIILFGEGFGNCKILAKKVYTLYSLAVQQLSRQDHYDFGLRALTSLLRYAGKKRR---------------------LQPDLSDEEVLLLSMRDMNIAKLTSVDVPLFNAIVQDLFPNIELPVIDYGKLRDTIEQ--EIREMGLQITPFT-----LTKVLQLYETKNSRHSTMIVGGTGSSKTTSWKILQASLTSLCRAGEPNYNIVREFPLNPKALSLGELYGEYDLNTNEWTDGILSSVMRV---ACADEKPDEKWILFDGPVDTLWIESMNSVMDDNKVLTLINGERIAMPEQVSLLFEVENLAVASPATVSRCGMVYTDYVDLGWKPYVQSWLEKRPKTEVEPLQRMFEKFINK---------------ILSFKKDNCNELVPVPEYSGIISLCKLYT---------------------VLATPENGVN--------PADAENYSFMVEMTFVFSMIWSVCASVDEDGRKKIDSYLREIE-------GSFPNKDTVYEYYVNPKMRTWTSFEEKLPKSWRYPPNAPFYKIMVPTVDTVRYNYLVSTLVANQNPVLLVGPVGTGKTSIAQSVLQSLPSSQWSVLVVNMSAQTTSNNVQSIIESRVEKRTKGVYVPFG----GKSMITFMDDLNMPAKDMFGSQPPLELIRLWIDY-GFWYDRVKQSIKHIRDMFLMAAMGPPGGGRTVISPRLQSRFNIINMTFPTESQIIRIFGTMINQKLQDFEEEVKPIGNVVTEATLDVYNTVVQRFLPTPAKIHYLFNLRDISKVFQGMLRANKDFHDTKA-SITRLWIHECFRVFSDRLVDTADMEAFMGILSDKLGTFFDLTFHHLCPN-------KRPPIFGDFLKE---PKVYEDLVDLTV--LKTAMETALNEYNLSPSVVPMQLVLFREAIEHITRIVRVIGQPRGNMLLVGIGGSGRQSLARLASSICDYNTFQIEVTKHYRKQEFRDDIKRLYRQAGVELQTTSFLFVDTQIADESFLEDINNILSSGEVPNLYKSDEFEEIQNHIIDQA-RAEQIPESSDSLFAYLIERVRNNLHIVLCLSPVGDPFRNWIRQYPALVNCTTINWFSEWPREALLEVAEKYIIGVDLGT------------------QENIHRKVA-QIFVTMHWSVAQYSQKMLLELRRYNYVTPTNYLELVSGYKKLLGEKRQELLDQANKLRTGLFKIDETREKVEVMSLELEDAKKKVAEFQKQCEEYLVIIVQQKREADEQQKAVTANSEKIAIEEVKCQALADNAQKDLEEALPALEEAMRALESLNKKDIGEIKSYGRPPAQVEIVMQAVMILRGNEPT-WAEAKRQLGEQNFIKSLINFDKDNISDKVLKKIGA-YCAQPDFQPDIIGRVSLAAKSLCMWVRAMELYGRLYRVVEPKRIRMNAAMAQLQEKQAALAEAQEKLREVAEKLEMLKKQYDEKLAQKEELRKKSEEMELKLERAGMLVSGLAGEKARWEETVQGLEEDLGYLVGDCLIAAAFLSYMGPFLTNYRDEIINQIWIRKIRELQVPCSPRFAIDNFLTNPTKVRDWNIQGLPSDAFSTENGIIVTRGNRWALMIDPQGQALKWIKNMEGNQGLKIIDLQMHDYLRVLEHAIQFGFPVLLQNVQEYLDPTLNPVLNKSVARIGGRMLIRIGDKEVEYNPNFRFYLTTKLSNPHYNPETSAKTTIVNFAVKEQGLEAQLLGIVVRKERPELEEQKDSLVINIAAGKRKLKELEDEILRLLNEATGSLLDDVQLVNTLQTSKITATEVTEQLETSETTEINIDLAREAYRPCAQRASVLFFVLNDMGRIDPMYQFSLDAYIGLF-ILSIDKSHRSN--KLEDRIEYLNDYHTYAVYRYTCRTLFERHKLLFSFHMCAKILETSGKLNM--DEYNFFLR---GGVVLDREGQMDNPCTSWLADAYWDNITELDKLTNFHGLMNSFEQYPRDWHLWYTNSSPEKAMLPGEW--ENACNE---------MQRMLIVRSLRQDRVAFCVTSFIVSNLGSRFIEP--PVLNMKSVME-DSTPRSPLVFILSPGVDPTSALLQLAEHTGMAHRFHALSLGQGQA-PIAARLLREGVNQGHWVFLANCHLSLSWMPNLDKLVEQLQVEDPHPSFRLWLSSSPHPDFPISILQASIKMTTEPPKGLKANMTRLYQLMTEAQFTHCSKPAKYKKLLFALCFFHSILLERKKFLQLGWNIIYGFNDSDFEVSENLLSLYLDEY---------EETPWDALKYLIAGVNYGGHVTDDWDRRLLTTYINDYFCDLSLTTPFYRLSVLD---TYYIPKDGSLASYKEYISMLPSMDPPEAFGQHPNADVASQITEARTLFETLLSLQPQITPTR--VGGQSREEKVLELAADVKQKIPEMIDYEGTRKLLALDP--------------SPLNVVLLQEIQRYNKLMKTILFSLTDLEKGIQGLIVMSTSLEEIFNCIFDAHVPPLWGK-VYPSQKPLASWTRDLAVRVEQF----ETWASR---ARPPVLFWLSGFTFPTGFLTAVLQSAARQNNISVDSL 4336
BLAST of Cytoplasmic dynein 1 heavy chain 1 vs. Ensembl Mouse
Match: Dnah10 (dynein, axonemal, heavy chain 10 [Source:MGI Symbol;Acc:MGI:1860299]) HSP 1 Score: 1365.9 bits (3534), Expect = 0.000e+0 Identity = 971/3364 (28.86%), Postives = 1699/3364 (50.51%), Query Frame = 3 Query: 3954 LEGKFNR-LKEERENVQKAKEALELTEIGVKPISEE-KVTNALSELHDLKNVWNELKSIWEKIRDMKETPWLSVQPRKLRQDIENLTAQLKELPNSFKQYASFEHVRTLLKMYMKVNASIVELKSEAIKERHWRMLMRKLNVSWSLNE-LQLGKVWDIDLVKNEEIIREVLAIAQGEKALEEYLRQITEVWKNYVLELTNY----QSKSKIIKGWDDLFNKVKEHINNVTSMKASPYFKQFEEEATAWEDRLNKINALFDVWIDVQRRWIYLDGIFAGSADIKVLLPVESQRFQSVSTEFLGLMKKVQKSPLVTDVLNIANVQRQLERLADLLGKIQKSLGEYLERQRSSFPRFYFVGDEDLLEIIGNSXXXXXXXXXXXXMFAGVHSIILSED---EKVILGMMSKEGEELRFISPVSIIEHPRINDWLTAMEKEMRVSLAKYLNVAVKEISGWRTESNIDKDKFMVWLDKYQAQIVVLAAQITWSEAVEASL-----ASGVSLESTMTVVHSTLNMLADTVLYEQPPVRRRKLEHLIIEYVHQRDVLRALHNDGVSSNKNFDWMSQMRFYFDPKQTDPLHQLSIHVANAKFHYGFEYLGVCDRLVQTPLTDRCYLTMTQALEARLGGSPFGPAGTGKTESVKSLGNQLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLSAVSQQIQGIQEALRELMVSKKDSINVELLGKQVHVNPDMAIFITMNPGYAGRSNLPDNLKKLFRSLAMTQPDRQLIAQVMLYSQGFRTAEVLAGKVVPFFKLCDEQLSPQSHYDFGLRALKSVLVSAGNVKRDRIKQEKEKIVARGEEINETAIAEQLPEQEILIQSVMETMVPKLIADDIPLLYSLLTDVFPGVEYRQAEMKRLREELRKV-SENKFLVYSDEPNTAGYLWVEKVLQLYQITTIHHGLMMVGPSGSGKTMACRVLLQALENIDGIEGVAHIIDPKSISKDSLYGYMDPNTREWTDGLFTHILRRIIDSVRGESNKRQWIVFDGDVDPEWVENLNSVLDDNKLLTLPNGERLAIPPNVRIMFEVQDLKYATLATVSRCGMVWFSEEVLTTGMILTHFLNELKKVQVMEGEEDFSVNQGDTGADADSKISSSPIIQLQTQVSSILAPFFTEDGLIAKCLD--YSTTLEHIMDFTRLRALTSLFSMIKQSIRNMIEYNQSHSDFPLNNEQIENYVAKSLISSVVWSMSGDSKLKVREQLSQYIKNISTVD----------LPTVGGIKNIIDFEVNIQ-GTWVAWSNKVPQIEVETHKITATDVVVPTMDTVRHEALLYTWLAEHRPVLLCGPPGSGKTMTLFSALRCLPDME--VVGLNFSSATTPELMLKTFDQYCEYRKTPNGIVLAPQQLNKWLIFFCDEINLPDMDKYGTQRVISFLRQMVEHHGFY-RITDMQWVSFERIQFVGACNPPTDPGRKPLSHRFLRHVPVVYVDYPGETSLKQIY--------STFNRAMLRMLPSLRGYADTLTNAMVEFFLKTQERFTHDMQPHYIYSPREMTRWVRGIHEALKPLESLSVEGLVRIWAHEALRLFQDRLVEEDERHWTDDNINEVALKHFPNINKEEALKRPILYSNW--LSKDYSAVTQEELRDYVKARLKVFYEEELD--------VPLVLFNQVLDHVLRIDRVFRQPQGHLLLIGVSGAGKTTLSRFVSWINGLSVFQVKVHNKYTAEDFDEDLRNVLRRSGCKGEKITFIMDESNVMDSSFLERMNTLLANGEVPGLFEGDELTTLMTQCKEGAIREGLMIDSQEELYKWFTQQICRNLHVVFTMNPSADGLKDKASTSPALFNRCVLNWFGDWSLEAYFQVGKEFTNRLDLERTDYKVPDTLPCIAEGLLPQNPIYRDVVVNALVFVHQTMHQANVRVQKRGGRTAAITPRHYLDLIAHYMKLSAEKRADLEEQQLHLNNGLKKIEQTVDQVEVMQRSLTKKRQELENMNEAANAKLKQMVQDQQEAEQKKTTGQALKEELAKQEQFVNEKQKTVKQELDQVEPTVNEAKQAVQNIRKKDIQEIKAMKNPPNAVKMAVESICLLLGEKTTDWQSILKVIIKDTFVTSILNFNTDDVSDNTRETMKKKYLSNPDYNFEKVNKASNACGPMVKWVLAQISYADILKRVEPLRNELTELSDAAEQNRKKSQETEDLIAQLEKSIAKYTEEYATLISQAQTIKSDLASVESKVGRSVALLGSLSSERTRWDSGSETFKAQMATINGDCLLSSAFMAYGGYFDQHMRTSLFN-TWCHHLSEADILFRSDLARVEYLSNPDDRL-RWQANSLPADDLCVENAIILRRYNRYPLIIDPSGQATTFLLNEYKEKKITKTSFLDDSFRKTLESALRFGTPLLVQDVESY-DPILNPVLNREVRRTGGRTLITLGDQDIDLSPTFTIFLSTRDPSVEFAPDICSRVTFVNFTVTRSSLQNQCLNAVLKIERPDIDQKRSDLLKAQGEFQLKLRHLEKDLLQSLNEAQGNLLENDKIIARLETLKREAADVAKKVEETDVVMQEVESVSTEYVPLAQSCSNIYFTLEAMNQIHFLYQYSLQLMLDIFSSVLINN-PELTNVKAASDRLKIITKNLFQVTYNRLARGMLHEDQITFATILARIF--LKGSTPIGFLENEFQHFLRSQEATITSSDSNKQDNLGLTLHQDQIDSVKRLKKLK-VFAKIEEKVKSTKDI-KNWTLTVTPESNVPELWVDDNNYNDEKLSKIAKGMYNLLIIQAIRPDRLLASTQKFIASVLGDTFTESVRGTLDLASIVEVEVTACVPILLCAVQGYDPSGRVEDLASEQ---GKQLTGIAIGSAEGFSQAEKAINSAAKTGKWVMLKNVHLATSWLVSLEKKIHSL-QAHPNFRLFLTMEITPKLPVNLLRAGRVLVFEPPPGIKANLLRTLSSINNQRMSKEPVERSR-LYFLLAWLNAIVQERLRYVPLGYSKKYEFGESDFKCALDTIDTWVDGAAMGRTNLPPEKIPWVALQTLLGSCIYGGKIDNAFDQRLLNSFLGYLFTEKCFD--HNFALVSDADDGSNIAFPESTKHTDILQWVHKLPDLQTPSWLGLPNSAEKVLLTNLGQSLIGNILKMQQSLEDDEELVVGQSKTKRTIEVGDGRPAWMRQLYQSTQT----WLQILPKSVTPLQRTIENIKDPMYRCFEREVNSGCNLLASVRKDLEDVAEVCKGAKKPTNHHRSMMADLAKGIIPKMWIRYAIPPGLTVIQWIQDFADRIKQLLHISDTAAKSGVIALRSIQVWLGGLFMAEAYITATRQSVAQNNKWALEE--LFLDVELGEGKVDSN-----TCVITGLRLMGSE 13817 L G F + L + +N Q+ A +L ++ + E KV ++ L + ++N LK E + +T W+++ + L++ IE L++LP + + H+ +K + +++LK EA++ERHW+ LM K V + + E L ++ ++L K+ E++ E++ A E A+E+ +++I + W+N + Y Q + I+ DD+ + ++ N+ S+ S + F + WE L+ I + ++W+ VQR+W+YL+ IF G DI+ LP E+++F ++ F +M + K P++ N L+ +++ L K QKSL +YL+ +R++FPRF+F+ D++LL I+GNS L + K M+ + + + EK++ M+S EGE + F + R+ DW+TA+ EMR + A+ R S +D W+ YQ +V+ A+Q+ W+ VE ++++ +HS ++ L + E R+K ++I VH RD++ + + + F+W SQ+RFY+D ++ D +L+I F YG+EY+G+ RLV TPLTDR YLT+TQAL LGG+P GPAGTGKTE+ K L LG +V NC E D++A+G+IF GL Q GAWGCFDEFNR++ +LS +S QIQ I+ AL + + + G+++ ++ M IFITMNPGYAGR+ LP+++K LFR + + PD Q I ++ML+S+GF A+ LA K+ +KL EQLS Q HYDFGLRALKSVLV AG +KR + L E +L++++ + +PK + +D+PL L++D+FPG++ + + + +V EN +++ + V+KV+Q+++ H M+VGP+G GK++ L QA + GI +I++PK++S LYG +DP TR+WTDG+ ++I R I + + +R++I+FDGDVD WVEN+NSV+DDNKLLTL NGER+ + + ++FEV DL+YA+ ATVSRCGMV+ + L +L +++ +K+ + L + L D +I +D L+ ++ T L +T L M+ + IE D L +E + ++L S+ S+ + ++K E + + + ++ TVD LP G + ++ DF + + W+ W+ VP+ V +H+ D++V T+DT R +L + PVL G G+ KT T + L+ L + V+ +NFSS TT + + + E R P + K L+ F D++N+P +D+YGTQ+ I+ L+ ++E Y R ++ S + F+ A GR + RFL V V +P E SL IY STFN ++ + L TL +V+ T +F HYI++ R+++R G+ P +V +VR+W +E LR+F DRL+ E ++ ++I + +HF N + E ++ PIL+ ++ ++ E+++DY A K +EE L+ + LVLF+ L+H+ R+ R+ R +GH LL+GV G+GK +L+R ++ G VF++ + Y+ +F +DL+N+ + G + + + F+ +++V + FLE +N +L +G VP LF +E ++ Q + A++ G M ++E ++++F + NLH+V M+P D L+ + P L N ++WF W +A V K F + +PD E L + +V +V VHQ++ + + + Q++ R+ +TP++YLD I Y KL EK Q L GL K+++ Q++ + L +++ L + A A L+++ + AE+KK + E+ +Q + + ++ + L +V P + AK +Q + K D+ EI++ PP V+ E I ++ G K +W++ ++ F+ S++ + D ++ + + K L + E++ S A M+K+V A + Y D+ + ++P R ++ L +++ + ++ +A ++K + +Y I + Q ++ + +E ++ + L+ L SE RW + + + + GDCLL +AF++Y G F R + N W + + + DI S R+E L D + RW + LP D+L V+N I+ R +R+PL IDP QA ++ + ++ + SF D F K LE ++++GTP L DV+ Y DP+++ VL + ++ + GR I LGD+++D F ++L+T+ + ++P + + +N+TVT L++Q L+ ++ ER +++++R L++ E + L+ LE LL+ L + GN+L+N +++ LE K +A +V++K++ + +++ + Y P A+ + ++F L M ++ +YQYSL L++F L + P+ +K RLK I L YN G+ ++ F+ + +G P + E FL+ I+ S + Q D + +K +F + ++ + + W + E L DDN LLI++ R DR+ + ++ +G+ + + + +I E + T PI+ G DP+ + LA G +L +A+G + A + + +A G+W+ML+N HL WL LEK + + + HP+FRL+LT + T P+ +L+ +V EPP G+K N+ T I+N + + P + L ++LA+ +A+VQER ++ +G++ Y+F ESDF+ ++ ++T++ A R +IPW +L+ L+G +YGG+ ++FD+R+L +++ + FD F + D I P ++ + LP TP GL ++AE T + + G++L++Q + G S+ +V M +++ Q L I P SV LQ E+ L+ + + L ++ G +N + L G IP +W + A T+ W+ F R Q + T + V+ WL GL + E+Y+TA Q+ + N W L+ LF V + + N C ++GL L G++ Sbjct: 1282 LLGSFEKELAKHEKNRQELANAEKLFDLPITMYPELIKVQKEMTGLRMIYELYNSLKLAKE---EWSQTLWINLNVQYLQEGIEGFLKNLRKLPRQVRGLSVAFHLEVKMKAFKDSIPLLLDLKHEALRERHWKELMEKTGVFFEMTETFTLENMFAMELHKHTEVLNEIVTAAVKEVAIEKAVKEILDTWENMKFTVVKYYKGTQERGYILGSVDDIIQCLDDNTVNLQSISGSRFVGPFLQTVHKWEKTLSLIGEVIEIWMLVQRKWMYLESIFIG-GDIRSQLPEEAKKFDNIDRIFKRIMGETLKDPVIKRCCEAPNRLHDLQTISEGLEKCQKSLNDYLDSKRNAFPRFFFISDDELLSILGNSDPLCVQEHMIK-MYDNIAMLRFHDGDSGEKLVSAMISAEGEVMTFRKIIR--ADGRVEDWMTAVLHEMRRTNRLITKEAIFRYCEDR--SRVD------WMLLYQGMVVLAASQVWWTWEVEDVFNKVKQGDKQAMKNYGKKMHSQIDDLVTRITMELSKNDRKKYNTVLIIDVHARDIVDSFIRGSILEAREFEWESQLRFYWD-REPD---ELNIRQCTGTFSYGYEYMGLNGRLVITPLTDRIYLTLTQALSMYLGGAPAGPAGTGKTETTKDLAKALGLLCVVTNCGEGMDYKAVGKIFSGLAQCGAWGCFDEFNRIDASVLSVISSQIQTIRNALIHQLTT------FQFEGQEISLDSRMGIFITMNPGYAGRTELPESVKALFRPVVVIVPDLQQICEIMLFSEGFLGAKTLAKKMTVLYKLAREQLSKQHHYDFGLRALKSVLVMAGELKRG---------------------SADLQEDVVLMRALRDMNLPKFVFEDVPLFLGLISDLFPGLDCPRVRYPDFNDAVEQVLEENGYVLLP--------VQVDKVVQMFETMLTRHTTMVVGPTGGGKSVVINTLCQAQTKL-GIMTKLYILNPKAVSVIELYGILDPTTRDWTDGVLSNIFREI--NRPTDKKERKYILFDGDVDALWVENMNSVMDDNKLLTLANGERIRLQAHCALLFEVGDLQYASPATVSRCGMVYVDPKNLKYQPYWKKWLQQIQ-----------------------NKVEQKYLNDLFEKYVPTLI-----DMIIEGIVDGRQGEKLKMVVPQTDLNMVTQLTRMLDSLLEGEIE------DLDL----LECFFLEALYCSLGSSLLEEGRVKFDECIKR-LSSMPTVDSEGNWARPGELP--GHLPSLYDFHFDAKRNHWIPWNKLVPEY-VHSHEKKFVDILVHTVDTTRTTWILEQMVKIKHPVLFVGESGTSKTATTQNFLKNLNEETNIVLIVNFSSRTTSLDIQRNLEANVEKRTKDT---YGP-PMGKRLLVFMDDMNMPKVDEYGTQQPIALLKLLLEKGYLYDRGKELNCKSIRDLGFIAAMG-KAGGGRNEVDPRFLSLFSVFNVPFPSEESLNLIYYSILKGHTSTFNESIGGVSRKLTFCTLTLYKNIVQDLPPTPSKF------HYIFNLRDLSRVFNGL-VLTNPDRFQTVSQMVRVWRNECLRVFHDRLINEVDKELVQNHIGNLVTEHF-NDDFEMVMRDPILFGDFRLALQEGEPRIYEDIQDYEAA--KALFEEILEEYNEVNTKMNLVLFDDALEHLTRVHRIIRMDRGHALLVGVGGSGKQSLARLAAFTAGCEVFEILLSRGYSENNFRDDLKNLYMKLGLENKMMIFLFTDAHVAEEGFLELINNMLTSGMVPALFAEEEKDNILGQIGQEALKFG-MGPAKESVWQFFVNKSANNLHIVLGMSPVGDTLRTRCRNFPGLVNNTGIDWFMPWPPQALHAVAKSFLG------DNSMIPD------EKL--------EELVEHVVMVHQSVGEFSKQFQQKLRRSNYVTPKNYLDFINTYSKLLDEKTQYNIAQCKRLEGGLDKLKEATIQLDELNLKLAEQKIVLAEKSAACEALLEEIATNTAIAEEKKKLAEEKAIEIEEQNKIIAVEKAEAETALAEVMPILEAAKLELQKLDKSDVTEIRSFAKPPKQVQTVCECILIMKGYKELNWKTAKGMMSDPNFLRSLMEIDFDSITQGQVKNI-KGLLKTLNTTIEEMEAVSKAGLGMLKFVEAVMGYCDVFREIKPKREKVARLERNFFLTKRELERIQNELAAIQKELEALGAKYEAAILEKQKLQEEAEIMERRLIAADKLISGLGSENVRWLNDLDELMHRRVKLLGDCLLCAAFLSYEGAFTWEFRDEMVNQVWQNDILDRDIPL-SQPFRLENLLTDDVEISRWGSQGLPPDELSVQNGILTTRASRFPLCIDPQQQALNWIKRKEEKNNLRVASFNDPDFLKQLEMSIKYGTPFLFHDVDEYIDPVIDSVLEKNIKTSQGRQFIILGDKEVDYDSNFRLYLNTKLANPRYSPSVFGKAMVINYTVTLKGLEDQLLSVLVAYERRELEEQREHLIQETSENKNLLKDLEDSLLRELATSTGNMLDNVELVQTLEETKSKATEVSEKLKLAEKTALDIDRLRDGYRPAARRGAILFFVLSEMALVNSMYQYSLIAFLEVFGLSLKKSLPDSILLK----RLKNIMDTLTFNIYNYGCTGLFERHKLLFSFNMTIKIEQAEGRVP----QEELDFFLK---GNISLEKSKWKKPCTWLSDQGWEDIILLSQKFSDIFGNLPLDIEHHLPMWQEWYDQDSLEQFPFPLGYDDN----------ITAFQKLLILRCFRVDRVYRAVTDYVTLTMGEKYVQP--PMISFEAIFE-QSTPNSPIVFILSPGSDPASDLMKLAERSGFGGTRLKFLAMGQGQE-KVALQLLETAVARGQWLMLQNCHLLVKWLKDLEKSLERITKPHPDFRLWLTTDPTKGFPIGILQKSLKVVTEPPNGLKLNMRATYFKISNDMLEQCPHTAFKPLVYVLAFFHAVVQERRKFGKIGWNVYYDFNESDFQVCMEILNTYLTKAFQQRD----PRIPWGSLKYLIGEVMYGGRAIDSFDRRILTTYMDEYLGDFIFDTFQPFHFFRNKDVDYKI--PVGDIKDKFVEAIEALPLANTPEVFGLHSNAEIGYYTQAARDMWGHLLELQPQTGESSS---GVSRDDYIGQVAKDIENKMPKIFDLDQVRKHLGLSITPTSVVLLQ----------------ELGRFNKLVIRMTRSLAELQRALAGEVGMSNELDDVARSLFLGHIPHIWRKLAPDTLKTLGNWMVYFLRRFSQYT-LWVTEGEPSVM-------WLSGLHIPESYLTALVQATCRRNGWPLDRSTLFTQVTKFQDADEVNERAGQGCFVSGLYLEGAD 4450
BLAST of Cytoplasmic dynein 1 heavy chain 1 vs. Ensembl Mouse
Match: Dnah2 (dynein, axonemal, heavy chain 2 [Source:MGI Symbol;Acc:MGI:107731]) HSP 1 Score: 1364.75 bits (3531), Expect = 0.000e+0 Identity = 986/3620 (27.24%), Postives = 1768/3620 (48.84%), Query Frame = 3 Query: 3126 VGLETESDNQKTYKKLLSSLPNSGESLENAYAAVHNILRDANEYVKTWTNYQSLWDLQGDQLFSLIADDNTVWMNVLEEIKSMRKHFDVAE-TQKEFGPLVIAF-----GKVQSKVSMKYDNWHKEVLTKFGQNMGKMMTTLYNEVQRARNELEQ--QSIDSGGTNESVNFITYTQNIKRKMNTWEKQAEACRAGQNILCRDRFQFPNDWLDS-ENIQGEWSAFKEIMRRKQETISSQVASLQMKITEEDKIVESKTTEVLGNWEKDKPIAGDLTPEEAVNIIQILEGKFNRLKEERENVQKAKEALELTEIGVKPISEEKVTNALSELHDLKNVWNELKSIWEKIRDMKET-------PWLSVQPRKLRQDIENLTAQLKELPNSFK--QYASFEHVRTLLKMYMKVNASIVELKSEAIKERHWRMLMRKLNVSWSLNE--LQLGKVWDIDLVKNEEIIREVLAIAQGEKALEEYLRQITEVWKNYVLELTNYQSKSKI-IKGWDDLFNKVKEHINNVTSMKASPYFKQFEEEATAWEDRLNKINALFDVWIDVQRRWIYLDGIFAGSADIKVLLPVESQRFQSVSTEFLGLMKKVQKSPLVTDVLNIANVQRQLERLADLLGKIQKSLGEYLERQRSSFPRFYFVGDEDLLEIIGNSXXXXXXXXXXXXMFAGVHSIIL-----SEDEKVILGMMSKEGEELRFISPVSIIEHPRINDWLTAMEKEMRVSLAKYLN---VAVKEISGWRTESNIDKDKFMVWLDKYQAQIVVLAAQITWSEAVEASLASGVSLESTMTVVH------STLNMLADTVLYEQPPVRRRKLEHLIIEYVHQRDVLRALHNDGVSSNKNFDWMSQMRFYFDPKQTDPLHQLSIHVANAKFHYGFEYLGVCDRLVQTPLTDRCYLTMTQALEARLGGSPFGPAGTGKTESVKSLGNQLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLSAVSQQIQGIQEALRELMVSKKDSINVELLGKQVHVNPDMAIFITMNPGYAGRSNLPDNLKKLFRSLAMTQPDRQLIAQVMLYSQGFRTAEVLAGKVVPFFKLCDEQLSPQSHYDFGLRALKSVLVSAGNVKRDRIKQEKEKIVARGEEINETAIAEQLPEQEILIQSVMETMVPKLIADDIPLLYSLLTDVFPGVEYRQAEMKRLREELRKVSENKFLVYSDEPNTAGYLWVEKVLQLYQITTIHHGLMMVGPSGSGKTMACRVLLQALENI-DGIEGVAHII-----DPKSISKDSLYGYMDPNTREWTDGLFTHILRRIIDSVRGESNKRQWIVFDGDVDPEWVENLNSVLDDNKLLTLPNGERLAIPPNVRIMFEVQDLKYATLATVSRCGMVWFSEEVLTTGMILTHFLNELKKVQVMEGEEDFS--VNQGDTGADADSKISSSPIIQLQTQVSSILAPFFTEDGLIAKCLDYSTTLEHIMDFTRLRALTSLFSMIKQSIRNMIEYNQSHSDFPLNNEQIENYVAKSLISSVVWSMSGDSKLKVREQLSQYIKNISTVDLPTVGGIKN---IIDFEVNIQ-GTWVAWSNKVPQIEVETHKITATDVVVPTMDTVRHEALLYTWLAEHRPVLLCGPPGSGKTMTLFSALRCLPDME--VVGLNFSSATTPELMLKTFDQYCEYRKTPNGIVLAPQQLNKWLIFFCDEINLPDMDKYGTQRVISFLRQMVEHHGFYRITDMQWVSFERIQFVGACNPPTDPGRKPLSHRFLRHVPVVYVDYPGETSLKQIYSTF-NRAMLRMLPSLRGYADTLTNAMVEFFLKTQERF-THDMQPHYIYSPREMTRWVRGIHEALKPLESLSVEGLVRIWAHEALRLFQDRLVEEDERHW----TDDNIN---EVALKHF-PNINKEEALKRPILYSNWLSKDYSAVTQEELRDYVKARLKVFYEEELD--------VP--LVLFNQVLDHVLRIDRVFRQPQGHLLLIGVSGAGKTTLSRFVSWINGLSVFQVKVHNKYTAEDFDEDLRNVLRRSGCKGEKITFIMDESNVMDSSFLERMNTLLANGEVPGLFEGDELTTLMTQCKEGAIREGLMIDSQEELYKWFTQQICRNLHVVFTMNPSADGLKDKASTSPALFNRCVLNWFGDWSLEAYFQVGKEFTNRLDLERTDYKVPDTLPCIAEGLLPQNPIYRDVVVNALVFVHQTMHQANVRVQKRGGRTAAITPRHYLDLIAHYMKLSAEKRADLEEQQLHLNNGLKKIEQTVDQVEVMQRSLTKKRQELENMNEAANAKLKQMVQDQQEAEQKKTTGQALKEELAKQEQFVNEKQKTVKQELDQVEPTVNEAKQAVQNIRKKDIQEIKAMKNPPNAVKMAVESICLLLGEKTTDWQSILKVIIKDTFVTSILNFNTDDVSDNTRETMKKKYLSNPDYNFEKVNKASNACGPMVKWVLAQISYADILKRVEPLRNELTELSDAAEQNRKKSQETEDLIAQLEKSIAKYTEEYATLISQAQTIKSDLASVESKVGRSVALLGSLSSERTRWDSGSETFKAQMATINGDCLLSSAFMAYGGYFDQHMRTSLFN-TWCHHLSEADILFRSDLARVEYLSNPDDRLRWQANSLPADDLCVENAIILRRYNRYPLIIDPSGQATTFLLNEYKEKKITKTSFLDDSFRKTLESALRFGTPLLVQDVESY-DPILNPVLNREVRRTGGRTLITLGDQDIDLSPTFTIFLSTRDPSVEFAPDICSRVTFVNFTVTRSSLQNQCLNAVLKIERPDIDQKRSDLLKAQGEFQLKLRHLEKDLLQSLNEAQGNLLENDKIIARLETLKREAADVAKKVEETDVVMQEVESVSTEYVPLAQSCSNIYFTLEAMNQIHFLYQYSLQLMLDIFSSVLINNPELTNVKAASDRLKIITKNLFQVTYNRLARGMLHEDQITFATILARIFLKGSTPIGFLENEFQHFLRSQEATITSSDSNKQDNLGLTLHQDQI-DSVKRLKKLKVFAKIEEKVKS-TKDIKNWTLTVTPE-SNVPELWVDDNNYNDEKLSKIAKGMYNLLIIQAIRPDRLLASTQKFIASVLGDTFTESVRGTLDLASIVEVEVTACVPILLCAVQGYDPSGRVEDLASEQG--KQLTGIAIGSAEGFSQAEKAINSAAKTGKWVMLKNVHLATSWLVSLEKKIHSLQA---HPNFRLFLTMEITPKLPVNLLRAGRVLVFEPPPGIKANLLRTLSSINNQRMS--KEPVERSRLYFLLAWLNAIVQERLRYVPLGYSKKYEFGESDFKCALDTIDTWVDGAAMGRTNLPPEKIPWVALQTLLGSCIYGGKIDNAFDQRLLNSFLGYLFTEKCFDHNFALVSDADDGSNIAFPESTKHTDILQWVHKLPDLQTPSWLGLPNSAEKVLLTNLGQSLIGNILKMQQSLEDDEELVVGQSKTKRTIEVGDGRPAWMRQL--YQSTQTWLQILPKSVTPLQRTIENIKDPMYRCFEREVNSGCNLLASVRKDLEDVAEVCKGAKKPTNHHRSMMADLAKGIIPKMWIRYAIPPGLTVIQWIQDFADRIKQLLHISDTAAKSGVIALRSIQVWLGGLFMAEAYITATRQSVAQNNKWALEEL 13736 V +E + D +K ++ S + N+ L+N Y+KTW Y+ +W++ D N + +I ++ +VA QKE L I F ++ + + W + T + + L++ ++ ++ Q+++ G + + ++ + E Q IL + P+ L+ E++ GEW F++I+ ++ + + + + K +L ++E P + A++ I + +++E N++ + +G+ I E+ V+ +L L+ + L+ +WE RD +E+ + ++Q + L +L L +K + E R+ ++ + + I +L++ A++ERHW + ++ + L ++ + + ++ E I E+ A A E A+E L+ I + W + L++ Y+ K ++G +++F ++++ +++MKAS + K FE++ WE L+ I + ++ + VQR+W+YL+ IF G DI+ LP ES F V+ + +M ++ K + + L + +L IQKSL YLE +R FPRFYF+ ++DLLEI+G S++ + +Q H KK F + + + S + +GM S +GE + F+ PV ++E P + WL +E+ MR++L L VA+K+ R DK W+ + Q+V+ A+QI W+ V L + + S LN ++ + + R K+ L+ +H RDVL L+ G+ +FDW+SQ+RFY++ D + I N +F YG+EYLG RLV TPLTDRCY+T+T AL GGSP GPAGTGKTE+VK LG LG +V+V NC E D+++MGR++ GL Q GAWGCFDEFNR+ +LS V+QQI I AL + G ++++ IFITMNPGYAGR+ LP+NLK +FR +AM PD LIA+++L+ +GF ++LA KV + L +QLS Q HYDFGLRAL S+L AG +R + L ++E+L+ S+ + + KL + D+PL +++ D+FP +E + +LR+ + + E + + P T + KVLQLY+ H M+VG +GS KT + ++L +L ++ E +I+ +PK++S LYG D NT EWTDG+ + ++R + E +WI+FDG VD W+E++NSV+DDNK+LTL NGER+A+P V ++FEV++L A+ ATVSRCGMV+ L + +L + K +V + F +N+ I+ + + L P G+I+ C Y+ + + N + P + E V + + S++WS+ R+++ Y++ I G N + ++ VN + TW ++ K+P+ ++VPT+DTVR+ L+ T +A PVLL GP G+GKT S L+ LP + V+ +N S+ TT + + E R + K +I F D++N+P D +G+Q + +R +++ GF+ Q + R F+ A P GR +S R ++ + +P E+ + +I+ T N+ + ++ + +T A ++ + +RF + HY+++ R++++ +G+ A K + R+W HE R+F DRLV+ + D + ++ H PN KRP ++ ++L + E+L D LK E L+ VP LVLF + ++H+ RI RV QP+G++LL+G+ G+G+ +L+R S I + FQ++V Y ++F +D++ + R++G + + +F+ ++ + D SFLE +N +L++GEVP L++ DE + + A R + +S + L+ + +++ NLH+V ++P D ++ PAL N +NWF +W EA +V +++ +DL Q I+R V V +H ++ Q + ++ R +TP +YL+L++ Y KL EKR +L +Q L GL KI++T ++VEVM L ++++ + L +VQ ++EA++++ A E++A +E +++L++ P + EA +A++++ KKDI EIK+ PP V++ ++++ +L G + T W + + + F+ S++NF+ D++SD + + Y + PD+ + + + S A + WV A Y + + VEP R + ++ + E ++ + ++ + + ++Y ++Q + ++ +E K+ R+ L+ L+ E+ RW+ + + + + GDCL+++AF++Y G F + R + N W + E + A +L+NP W LP+D EN II+ R NR+ L+IDP GQA ++ N + + + + LE A++FG P+L+Q+V+ Y DP LNPVLN+ V R GGR LI +GD++++ +P F +L+T+ + + P+ ++ T VNF V L+ Q L V++ ERP++++++ L+ + KL+ LE ++L+ LNEA G+LL++ +++ L+T K A +V +++E ++ ++ Y P AQ S ++F L M +I +YQ+SL + +F + I+ +N DR++ + Y R + ++ F+ + L+ S + +E+ FLR + + DN + D D++ L KL F + + +D W +PE + +P W +N N+ M +LI++++R DR+ FI S LG F E L++ S++E + T P++ G DP+ + LA G + +++G + A + + G WV L N HL+ SW+ +L+K + LQ HP+FRL+L+ P P+++L+A + EPP G+KAN+ R + + + +P + +L F L + ++I+ ER +++ LG++ Y F +SDF+ + + + ++D E+ PW AL+ L+ YGG + + +D+RLL +++ F + F +S D P+ +++ LP + P G +A+ ++L +L +Q + V GQS+ ++ +E+ + ++ Y+ T+ L + P P+ +E+ L+ ++ L D+ + +G + + + +P +W + P + W +D A R++Q +T A A + WL G ++TA QS A+ N +++ L Sbjct: 961 VLVERDEDIRKIQAQISSGMTNNASLLQN--------------YLKTWDMYREIWEINKDSFIRRYQRLNPPVSSFDADIA---RYTEVANNVQKEETVLNIQFVMLDCSHLKFSLVQHCNEWQNKFTTLLKEMAAGRLADLHSYLKDNAEKISHPPQTLEELGVS-----LQLMDTLQHDLPNLETQIPPIHEQFTILEKYEVPVPDTVLEMLESLNGEWLTFQQILLDSEQMLKKHKEKFKTGLIHAADDFKKKAHNLLEDFEFKGPFTSTVGHTAALDQIAQMRAMLMAMRDEENNLR--------SNLGIFKI-EQPVSK---DLQILEKELDALQQVWEITRDWEESWNQWKMGCFQTLQTEAMESMAHGLFRRLTRLAKEYKDRNWEIIETTRSKIEQFKRTMPLISDLRNPALRERHWDQVKEEVQREFDQESESFTLEQIVKLGMDQHVEKIAEISASATKELAIEVGLQNIAKTWDSTQLDIVPYKDKGHHRLRGTEEVFQALEDNQVALSTMKASRFVKAFEKDVDHWERCLSLILEVIEMVLTVQRQWMYLENIFLGE-DIRKQLPNESALFDQVNNNWKAIMDRMNKDNNALRSTHYPGLLETLIEMNAILEDIQKSLDMYLETKRHIFPRFYFLSNDDLLEILGQSRNPEAVQPHLKKCFDNIKLLKIQKVGGSSSKWEAVGMFSGDGEYIDFLHPV-LLEGP-VESWLGDVERAMRMTLRDLLRNCRVALKKFLNKR-------DK---WVKDWAGQVVITASQIQWTADVTKCLMTAKERSDKKILKVMKKKQVSILNKYSEAIRGNLTKIMRLKIVALVTIEIHARDVLEKLYKSGLMDVSSFDWLSQLRFYWEKDVDDCI----IRQTNTQFQYGYEYLGNSGRLVITPLTDRCYMTLTTALHLHRGGSPKGPAGTGKTETVKDLGKALGIYVIVVNCSEGLDYKSMGRMYSGLAQSGAWGCFDEFNRINIEVLSVVAQQILSILSAL------TANLTRFYFEGFEINLVWSCGIFITMNPGYAGRTELPENLKSMFRPIAMVVPDSTLIAEIILFGEGFGNCKILAKKVYTLYSLAVQQLSRQDHYDFGLRALTSLLRYAGKKRR---------------------LQPDLSDEEVLLLSMRDMNIAKLTSVDVPLFNAIVQDLFPNIELPVIDYGKLRDTIEQ--EIREMGLQITPFT-----LTKVLQLYETKNSRHSTMIVGGTGSSKTTSWKILQASLTSLCRAGEPNYNIVREFPLNPKALSLGELYGEYDLNTNEWTDGILSSVMRV---ACADEKPDEKWILFDGPVDTLWIESMNSVMDDNKVLTLINGERIAMPEQVSLLFEVENLAVASPATVSRCGMVYTDYVDLGWKPYVQSWLEKRPKTEVEPLQRMFEKFINK---------------ILSFKKDNCNELVPVPEYSGIISLCKLYT---------------------VLATPENGVN--------PADAENYSFMVEMTFVFSMIWSVCASVDEDGRKKIDSYLREIE-------GSFPNKDTVYEYYVNPKMRTWTSFEEKLPKSWRYPPNAPFYKIMVPTVDTVRYNYLVSTLVANQNPVLLVGPVGTGKTSIAQSVLQSLPSSQWSVLVVNMSAQTTSNNVQSIIESRVEKRTKGVYVPFG----GKSMITFMDDLNMPAKDMFGSQPPLELIRLWIDY-GFWYDRVKQSIKHIRDMFLMAAMGPPGGGRTVISPRLQSRFNIINMTFPTESQIIRIFGTMINQKLQDFEEEVKPIGNVVTEATLDVYNTVVQRFLPTPAKIHYLFNLRDISKVFQGMLRANKDFHDTKA-SITRLWIHECFRVFSDRLVDTADMEAFMGILSDKLGTFFDLTFHHLCPN-------KRPPIFGDFLKE---PKVYEDLVDLTV--LKTAMETALNEYNLSPSVVPMQLVLFREAIEHITRIVRVIGQPRGNMLLVGIGGSGRQSLARLASSICDYNTFQIEVTKHYRKQEFRDDIKRLYRQAGVELQTTSFLFVDTQIADESFLEDINNILSSGEVPNLYKSDEFEEIQNHIIDQA-RAEQIPESSDSLFAYLIERVRNNLHIVLCLSPVGDPFRNWIRQYPALVNCTTINWFSEWPREALLEVAEKYIIGVDLGT------------------QENIHRKVA-QIFVTMHWSVAQYSQKMLLELRRYNYVTPTNYLELVSGYKKLLGEKRQELLDQANKLRTGLFKIDETREKVEVMSLELEDAKKKVAEFQKQCEEYLVIIVQQKREADEQQKAVTANSEKIAIEEVKCQALADNAQKDLEEALPALEEAMRALESLNKKDIGEIKSYGRPPAQVEIVMQAVMILRGNEPT-WAEAKRQLGEQNFIKSLINFDKDNISDKVLKKIGA-YCAQPDFQPDIIGRVSLAAKSLCMWVRAMELYGRLYRVVEPKRIRMNAAMAQLQEKQAALAEAQEKLREVAEKLEMLKKQYDEKLAQKEELRKKSEEMELKLERAGMLVSGLAGEKARWEETVQGLEEDLGYLVGDCLIAAAFLSYMGPFLTNYRDEIINQIWIRKIRELQVPCSPRFAIDNFLTNPTKVRDWNIQGLPSDAFSTENGIIVTRGNRWALMIDPQGQALKWIKNMEGNQGLKIIDLQMHDYLRVLEHAIQFGFPVLLQNVQEYLDPTLNPVLNKSVARIGGRMLIRIGDKEVEYNPNFRFYLTTKLSNPHYNPETSAKTTIVNFAVKEQGLEAQLLGIVVRKERPELEEQKDSLVINIAAGKRKLKELEDEILRLLNEATGSLLDDVQLVNTLQTSKITATEVTEQLETSETTEINIDLAREAYRPCAQRASVLFFVLNDMGRIDPMYQFSLDAYIGLF-ILSIDKSHRSN--KLEDRIEYLNDYHTYAVYRYTCRTLFERHKLLFSFHMCAKILETSGKLNM--DEYNFFLR---GGVVLDREGQMDNPCTSWLADAYWDNITELDKLTNFHGLMNSFEQYPRDWHLWYTNSSPEKAMLPGEW--ENACNE---------MQRMLIVRSLRQDRVAFCVTSFIVSNLGSRFIEP--PVLNMKSVME-DSTPRSPLVFILSPGVDPTSALLQLAEHTGMAHRFHALSLGQGQA-PIAARLLREGVNQGHWVFLANCHLSLSWMPNLDKLVEQLQVEDPHPSFRLWLSSSPHPDFPISILQASIKMTTEPPKGLKANMTRLYQLMTEAQFTHCSKPAKYKKLLFALCFFHSILLERKKFLQLGWNIIYGFNDSDFEVSENLLSLYLDEY---------EETPWDALKYLIAGVNYGGHVTDDWDRRLLTTYINDYFCDLSLTTPFYRLSVLD---TYYIPKDGSLASYKEYISMLPSMDPPEAFGQHPNADVASQITEARTLFETLLSLQPQITPTR--VGGQSREEKVLELAADVKQKIPEMIDYEGTRKLLALDP--------------SPLNVVLLQEIQRYNKLMKTILFSLTDLEKGIQGLIVMSTSLEEIFNCIFDAHVPPLWGK-VYPSQKPLASWTRDLAVRVEQF----ETWASR---ARPPVLFWLSGFTFPTGFLTAVLQSAARQNNISVDSL 4342
BLAST of Cytoplasmic dynein 1 heavy chain 1 vs. UniProt/SwissProt
Match: sp|Q14204|DYHC1_HUMAN (Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5) HSP 1 Score: 6147 bits (15946), Expect = 0.000e+0 Identity = 2962/4618 (64.14%), Postives = 3666/4618 (79.39%), Query Frame = 3 Query: 261 ECLTKFINDNQVTTLTIQQ-TKRXXXXXXXXXXXXKISNEVNFESN---KSQTSIFIKNNQVIEADKTISSQLQVLSYCDGPPFETMHSLVCYGLLPYFXXXXXXXXXXXXXXXXXMVPSVEKKIAELEIGLLHLQQNIEIPEITLTPHPYVAHIIQEKLLQNKEARVSDFEDKFEDTQFLNQLQAGVNRWIKEIQKVTKLNRDPSTGTALQEISFWLNLEHSLDKIQEKRESLEVALTLAILKQAKRFHATTSFDTDTALSSAKIQVKDYNQLMKDFPINDLLSASQLDKISEALQQIFSHLKKVRATKYPVNRIIKLMEALSRDLTTQLMKVISNMHLMSMPYDEFEKIFTACQQVFSTWEDEYDKMQNLLRDIAKKKREEFTKFAWKMNATHKKLQTRLENIKKFRYQHEQLRQVIVRVLKP-VTKVVPSVEAGVPKDQITDKGDKSSTFLPESADTSSIDEVNAAYEIVKVIDCLDFAKEENDEWDAAIKRYEERIDRVESRIASHLRDLLGQSKNANEMFRYFSRFNALFVRPHIRGAIGEYQTQLIQRVKDDIEALHNKFKVQYASSTACKMSKVRDLPPVSGSIIWVRQILRQLNAYMKRVEDVLGKDWAQHIEGQKLKADGESFKLKLNTSELFEEWSKKVAEKSLSVAGSIFNVESTRTVVTVRDREPQKITVLKLKVNFLPDVITLAKEVRNMRALGFRTPLSIVNKAHSANQLYPFAISLIESVRTYESTCSKIEEHKMQNISLLTAGLRKDVQLCIHEGVQITWESYRLDQYVQKLAELVFSFQEKVDDLVIVIKEIDFNVKALETCSYNKQTFEEILIRIQEAVDNMSLHQFSNLAQWVSNLDSLVEQRLIVRLEAGLLEWIKVLKGXXXXXXXXXXXXXXXVNSMAKHRLGGKPQIKKLIHELRITNQQMHLYPSIEVATQDILYQMSSWQNIILNLSRIVHSRYQVGLETE-SDNQKTYKKLLSSLPNSGESLENAYAAVHNILRDANEYVKTWTNYQSLWDLQGDQLFSLIADDNTVWMNVLEEIKSMRKHFDVAETQKEFGPLVIAFGKVQSKVSMKYDNWHKEVLTKFGQNMGKMMTTLYNEVQRARNELEQQSIDSGGTNESVNFITYTQNIKRKMNTWEKQAEACRAGQNILCRDRFQFPNDWLDSENIQGEWSAFKEIMRRKQETISSQVASLQMKITEEDKIVESKTTEVLGNWEKDKPIAGDLTPEEAVNIIQILEGKFNRLKEERENVQKAKEALELTEIGVKPISEEKVTNALSELHDLKNVWNELKSIWEKIRDMKETPWLSVQPRKLRQDIENLTAQLKELPNSFKQYASFEHVRTLLKMYMKVNASIVELKSEAIKERHWRMLMRKLNVSWSLNELQLGKVWDIDLVKNEEIIREVLAIAQGEKALEEYLRQITEVWKNYVLELTNYQSKSKIIKGWDDLFNKVKEHINNVTSMKASPYFKQFEEEATAWEDRLNKINALFDVWIDVQRRWIYLDGIFAGSADIKVLLPVESQRFQSVSTEFLGLMKKVQKSPLVTDVLNIANVQRQLERLADLLGKIQKSLGEYLERQRSSFPRFYFVGDEDLLEIIGNSXXXXXXXXXXXXMFAGVHSIILSEDEKVILGMMSKEGEELRFISPVSIIEHPRINDWLTAMEKEMRVSLAKYLNVAVKEISGWRTESNIDKDKFMVWLDKYQAQIVVLAAQITWSEAVEASLAS------GVSLESTMTVVHSTLNMLADTVLYEQPPVRRRKLEHLIIEYVHQRDVLRALHNDGVSSNKNFDWMSQMRFYFDPKQTDPLHQLSIHVANAKFHYGFEYLGVCDRLVQTPLTDRCYLTMTQALEARLGGSPFGPAGTGKTESVKSLGNQLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLSAVSQQIQGIQEALRELMVSKKDS----INVELLGKQVHVNPDMAIFITMNPGYAGRSNLPDNLKKLFRSLAMTQPDRQLIAQVMLYSQGFRTAEVLAGKVVPFFKLCDEQLSPQSHYDFGLRALKSVLVSAGNVKRDRIKQEKEKIVARGEEINETAIAEQLPEQEILIQSVMETMVPKLIADDIPLLYSLLTDVFPGVEYRQAEMKRLREELRKVSENKFLVYSDEPNTAGYLWVEKVLQLYQITTIHHGLMMVGPSGSGKTMACRVLLQALENIDGIEGVAHIIDPKSISKDSLYGYMDPNTREWTDGLFTHILRRIIDSVRGESNKRQWIVFDGDVDPEWVENLNSVLDDNKLLTLPNGERLAIPPNVRIMFEVQDLKYATLATVSRCGMVWFSEEVLTTGMILTHFLNELKKVQVMEGEEDFSVNQGDTGADADSKISSSPIIQLQTQVSSILAPFFTEDGLIAKCLDYSTTLEHIMDFTRLRALTSLFSMIKQSIRNMIEYNQSHSDFPLNNEQIENYVAKSLISSVVWSMSGDSKLKVREQLSQYIKNISTVDLPTVGGIKNIIDFEVNIQGTWVAWSNKVPQIEVETHKITATDVVVPTMDTVRHEALLYTWLAEHRPVLLCGPPGSGKTMTLFSALRCLPDMEVVGLNFSSATTPELMLKTFDQYCEYRKTPNGIVLAPQQLNKWLIFFCDEINLPDMDKYGTQRVISFLRQMVEHHGFYRITDMQWVSFERIQFVGACNPPTDPGRKPLSHRFLRHVPVVYVDYPGETSLKQIYSTFNRAMLRMLPSLRGYADTLTNAMVEFFLKTQERFTHDMQPHYIYSPREMTRWVRGIHEALKPLESLSVEGLVRIWAHEALRLFQDRLVEEDERHWTDDNINEVALKHFPNINKEEALKRPILYSNWLSKDYSAVTQEELRDYVKARLKVFYEEELDVPLVLFNQVLDHVLRIDRVFRQPQGHLLLIGVSGAGKTTLSRFVSWINGLSVFQVKVHNKYTAEDFDEDLRNVLRRSGCKGEKITFIMDESNVMDSSFLERMNTLLANGEVPGLFEGDELTTLMTQCKEGAIREGLMIDSQEELYKWFTQQICRNLHVVFTMNPSADGLKDKASTSPALFNRCVLNWFGDWSLEAYFQVGKEFTNRLDLERTDYKVPDTLPCIAEGLLPQNPIYRDVVVNALVFVHQTMHQANVRVQKRGGRTAAITPRHYLDLIAHYMKLSAEKRADLEEQQLHLNNGLKKIEQTVDQVEVMQRSLTKKRQELENMNEAANAKLKQMVQDQQEAEQKKTTGQALKEELAKQEQFVNEKQKTVKQELDQVEPTVNEAKQAVQNIRKKDIQEIKAMKNPPNAVKMAVESICLLLGEKTTDWQSILKVIIKDTFVTSILNFNTDDVSDNTRETMKKKYLSNPDYNFEKVNKASNACGPMVKWVLAQISYADILKRVEPLRNELTELSDAAEQNRKKSQETEDLIAQLEKSIAKYTEEYATLISQAQTIKSDLASVESKVGRSVALLGSLSSERTRWDSGSETFKAQMATINGDCLLSSAFMAYGGYFDQHMRTSLFNTWCHHLSEADILFRSDLARVEYLSNPDDRLRWQANSLPADDLCVENAIILRRYNRYPLIIDPSGQATTFLLNEYKEKKITKTSFLDDSFRKTLESALRFGTPLLVQDVESYDPILNPVLNREVRRTGGRTLITLGDQDIDLSPTFTIFLSTRDPSVEFAPDICSRVTFVNFTVTRSSLQNQCLNAVLKIERPDIDQKRSDLLKAQGEFQLKLRHLEKDLLQSLNEAQGNLLENDKIIARLETLKREAADVAKKVEETDVVMQEVESVSTEYVPLAQSCSNIYFTLEAMNQIHFLYQYSLQLMLDIFSSVLINNPELTNVKAASDRLKIITKNLFQVTYNRLARGMLHEDQITFATILARIFLKGSTPIGFLENEFQHFLRSQEATITSSDSNKQDNLGLTLHQDQIDSVKRLKKLKVFAKIEEKVKSTKDIKNWTLTVTPESNVPELWVDDNNYNDEKLSKIAKGMYNLLIIQAIRPDRLLASTQKFIASVLGDTFTESVRGTLDLASIVEVEVTACVPILLCAVQGYDPSGRVEDLASEQGKQLTGIAIGSAEGFSQAEKAINSAAKTGKWVMLKNVHLATSWLVSLEKKIHSLQAHPNFRLFLTMEITPKLPVNLLRAGRVLVFEPPPGIKANLLRTLSSINNQRMSKEPVERSRLYFLLAWLNAIVQERLRYVPLGYSKKYEFGESDFKCALDTIDTWVDGAAMGRTNLPPEKIPWVALQTLLGSCIYGGKIDNAFDQRLLNSFLGYLFTEKCFDHNFALVSDADDGSNIAFPESTKHTDILQWVHKLPDLQTPSWLGLPNSAEKVLLTNLGQSLIGNILKMQQSLEDDEELVVGQSKTK-RTIEVGDGRPAWMRQLYQSTQTWLQILPKSVTPLQRTIENIKDPMYRCFEREVNSGCNLLASVRKDLEDVAEVCKGAKKPTNHHRSMMADLAKGIIPKMWIRYAIPPGLTVIQWIQDFADRIKQLLHISDTAAKSGVIALRSIQVWLGGLFMAEAYITATRQSVAQNNKWALEELFLDVELGEGK---VDSNTCVITGLRLMGSEIVDPRTLKLSTLIYKDIDICRLKWIRVEKSQQLEGSSAKDKVCLPIYLNAARSTVLFTLYF--STTDSSYDFYKRGVAI 14048 E + KF++D QV T+ +++ T +E+ E IS +N + + KS + FIK VI+ADK +SSQL+VL+ + P+ET+HS + + P+FKSYI++ GK M PSVEKKIAELE+GLLHLQQNIEIPEI+L HP + ++ ++ + ++ +V+DF DK ED FLNQLQ+GVNRWI+EIQKVTKL+RDP++GTALQEISFWLNLE +L +IQEKRES EV LTL ILK KRFHAT SFDTDT L A V DYN LMKDFP+NDLLSA++LDKI +AL IF+HL+K+R TKYP+ R ++L+EA+SRDL++QL+KV+ LM + Y+EFEK+ AC +VF TW+DEY+K+Q LLRDI K+KREE K W++N H+KLQ RL+ ++KFR QHEQLR VIVRVL+P VT V + VP+ Q K + L ++AD ++I+EVN AYE VK +D LD +KE + W+AA+KRY+ERIDRVE+RI + LRD LG +KNANEMFR FSRFNALFVRPHIRGAI EYQTQLIQRVKDDIE+LH+KFKVQY S ACKMS VRDLPPVSGSIIW +QI RQL AYMKRVEDVLGK W H+EGQKLK DG+SF++KLNT E+F++W++KV +++L V+G IF +ESTR VR R VLKLKVNFLP++ITL+KEVRN++ LGFR PL+IVNKAH ANQLYPFAISLIESVRTYE TC K+EE ISLL AGL+K+VQ I EG+ + WESY+LD YVQ+LAE VF+FQEKVDDL+I+ ++ID V++LETC Y+ +TF EIL R+Q+AVD+++LH +SNL WV+ LD +E+ L VRL+AGL W +VL G+ + E D DTD H+ GG+P+IK ++HELRITNQ ++L P IE + +M +W+ ++L+L RI RYQVG+ E ++ +K Y+ L+ +P+ +LE +Y+AV I+ + +YVK W YQ LWD+Q + +++ + +D W +L +I+ R FD AET+KEFGP+VI +GKVQSKV++KYD+WHKEVL+KFGQ +G MT ++++ ++R ELEQ S+D+ T+++V FITY Q++KRK+ +EKQ E R GQ +L + RFQFP WL +NI+GEW AF +IMRRK I QVA+LQMKI +ED+ VES+TT++L +WEK KP+ G+L PEEA+ + I EGKF RLK++RE KAKEALELT+ G+ SEE+V AL EL DLK VW+EL +WE+I MKE PW+SVQPRKLRQ+++ L QLK P +QYAS+E V+ LLK YMK+N ++ELKSEA+K+RHW+ LM++L+V+W ++EL LG++WD+DL KNE I+++VL +AQGE ALEE+L+QI EVW Y L+L NYQ+K ++I+GWDDLFNKVKEHIN+V++MK SPY+K FEE+A +WED+LN+I ALFDVWIDVQRRW+YL+GIF GSADIK LLPVE+QRFQS+STEFL LMKKV KSPLV DVLNI VQR LERLADLLGKIQK+LGEYLER+RSSFPRFYFVGDEDLLEIIGNSK++ KLQKHFKKMFAGV SIIL+ED V+LG+ S+EGEE+ F +PVSI EHP+IN+WLT +EKEMRV+LAK L +V E+ + ++ID + ++ W+DKYQAQ+VVL+AQI WSE VE +L+S L S ++ V TLN+LAD+VL EQPP+RRRKLEHLI E VHQRDV R+L + + K+F+W+SQMRFYFDPKQTD L QLSI +ANAKF+YGFEYLGV D+LVQTPLTDRCYLTMTQALEARLGGSPFGPAGTGKTESVK+LG+QLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLSAVSQQ+Q IQEALRE D I ELL KQV V+PDMAIFITMNPGYAGRSNLPDNLKKLFRSLAMT+PDRQLIAQVMLYSQGFRTAEVLA K+VPFFKLCDEQLS QSHYDFGLRALKSVLVSAGNVKR+RI++ K + RGE ++E IAE LPEQEILIQSV ETMVPKL+A+DIPLL+SLL+DVFPGV+Y + EM LREEL+KV + +L Y D G +WVEKVLQLYQIT I+HGLMMVGPSGSGK+MA RVLL+ALE ++G+EGVAHIIDPK+ISKD LYG +DPNTREWTDGLFTH+LR+IIDSVRGE KRQWIVFDGDVDPEWVENLNSVLDDNKLLTLPNGERL++PPNVRIMFEVQDLKYATLATVSRCGMVWFSE+VL+T MI +FL L+ + + EGE++ + G + + + ++SP++Q+Q ++I+ P+FT +GL+ K L+++ LEHIMD TRLR L SLFSM+ Q+ RN+ +YN +H DFP+ EQ+E Y+ + L+ +++WS+SGDS+LK+R +L +YI+ I+TV LPT I IID+EV+I G W W KVPQIEVETHK+ A DVVVPT+DTVRHEALLYTWLAEH+P++LCGPPGSGKTMTLFSALR LPDMEVVGLNFSSATTPEL+LKTFD YCEYR+TPNG+VLAP QL KWL+ FCDEINLPDMDKYGTQRVISF+RQMVEH GFYR +D WV ERIQFVGACNPPTDPGRKPLSHRFLRHVPVVYVDYPG SL QIY TFNRAMLR++PSLR YA+ LT AMVEF+ +QERFT D QPHYIYSPREMTRWVRGI EAL+PLE+L VEGL+RIWAHEALRLFQDRLVE++ER WTD+NI+ VALKHFPNI++E+A+ RPILYSNWLSKDY V QEELRDYVKARLKVFYEEELDVPLVLFN+VLDHVLRIDR+FRQPQGHLLLIGVSGAGKTTLSRFV+W+NGLSV+Q+KVH KYT EDFDEDLR VLRRSGCK EKI FIMDESNV+DS FLERMNTLLANGEVPGLFEGDE TLMTQCKEGA +EGLM+DS EELYKWFT Q+ RNLHVVFTMNPS++GLKD+A+TSPALFNRCVLNWFGDWS EA +QVGKEFT+++DLE+ +Y VPD +P + + L PQ P +R+ +VN+ VFVHQT+HQAN R+ KRGGRT AITPRHYLD I HY L EKR++LEEQQ+HLN GL+KI++TVDQVE ++R L K QELE N AAN KLK+MV+DQQEAE+KK Q ++E+L KQ++ + +KQ +VK++LD+VEP V EA+ AV++I+K+ + E+++M NPP AVK+A+ESICLLLGE TTDW+ I +I+++ F+ +I+NF+ +++SD RE MKK Y+SNP YN+E VN+AS ACGPMVKW +AQ++YAD+LKRVEPLRNEL +L D A+ N++K+ E E +I LE SIA+Y EEYA LIS+AQ IK+DLA+VE+KV RS ALL SLS+ER RW+ SETFK QM+TI GDCLLS+AF+AY GYFDQ MR +LF TW HHL +A+I FR+D+AR EYLSN D+RLRWQA+SLPADDLC ENAI+L+R+NRYPLIIDPSGQAT F++NEYK++KIT+TSFLDD+FRK LESALRFG PLLVQDVESYDP+LNPVLNREVRRTGGR LITLGDQDIDLSP+F IFLSTRDP+VEF PD+CSRVTFVNFTVTRSSLQ+QCLN VLK ERPD+D+KRSDLLK QGEFQL+LR LEK LLQ+LNE +G +L++D II LE LKREAA+V +KVEETD+VMQEVE+VS +Y+PL+ +CS+IYFT+E++ QIHFLYQYSLQ LDI+ +VL NP L V + RL IITK+LFQV +NR+ARGMLH+D ITFA +LARI LKG+ + EFQHFLR E +++ + + GLT+ +Q ++V RL L F + KV++ + W + +PE VP LW ++ + I + ++ LL+IQA RPDRLLA F+++ LG++F + LDL IV EV P+L+C+V GYD SG VEDLA+EQ Q+T IAIGSAEGF+QA+KAIN+A K+G+WVMLKNVHLA WL+ LEKK+HSLQ H FRLFLTMEI PK+PVNLLRAGR+ VFEPPPG+KAN+LRT SSI R+ K P ER+RLYFLLAW +AI+QERLRY PLG+SKKYEFGESD + A DT+DTW+D A GR N+ P+KIPW AL+TL+ IYGG++DN FDQRLLN+FL LFT + FD F L D +I P+ + + +QWV LPD QTPSWLGLPN+AE+VLLT G +I +LKMQ LED+++L +++ K RT DGRPAWMR L+ + WL ++P++++ L+RT+ENIKDP++R FEREV G LL VR+DL DV +VC+G KK TN+ R+++ +L KGI+P+ W Y +P G+TVIQW+ DF++RIKQL +IS AA G L++I V LGGLF+ EAYITATRQ VAQ N W+LEEL L+V + + +D+ + +TGL+L G+ + L LS I + + +L+W++ Q V LP+YLN R+ ++FT+ F +T + FY+RGVA+ Sbjct: 63 EQMRKFLSDPQVHTVLVERSTLKEDVGDEGEEEKEFISYNINIDIHYGVKSNSLAFIKRTPVIDADKPVSSQLRVLTLSEDSPYETLHSFISNAVAPFFKSYIRESGKADRDGDK-MAPSVEKKIAELEMGLLHLQQNIEIPEISLPIHPMITNVAKQCYERGEKPKVTDFGDKVEDPTFLNQLQSGVNRWIREIQKVTKLDRDPASGTALQEISFWLNLERALYRIQEKRESPEVLLTLDILKHGKRFHATVSFDTDTGLKQALETVNDYNPLMKDFPLNDLLSATELDKIRQALVAIFTHLRKIRNTKYPIQRALRLVEAISRDLSSQLLKVLGTRKLMHVAYEEFEKVMVACFEVFQTWDDEYEKLQVLLRDIVKRKREENLKMVWRINPAHRKLQARLDQMRKFRRQHEQLRAVIVRVLRPQVTAVAQQNQGEVPEPQDM----KVAEVLFDAADANAIEEVNLAYENVKEVDGLDVSKEGTEAWEAAMKRYDERIDRVETRITARLRDQLGTAKNANEMFRIFSRFNALFVRPHIRGAIREYQTQLIQRVKDDIESLHDKFKVQYPQSQACKMSHVRDLPPVSGSIIWAKQIDRQLTAYMKRVEDVLGKGWENHVEGQKLKQDGDSFRMKLNTQEIFDDWARKVQQRNLGVSGRIFTIESTR----VRGRTG---NVLKLKVNFLPEIITLSKEVRNLKWLGFRVPLAIVNKAHQANQLYPFAISLIESVRTYERTCEKVEERN--TISLLVAGLKKEVQALIAEGIALVWESYKLDPYVQRLAETVFNFQEKVDDLLIIEEKIDLEVRSLETCMYDHKTFSEILNRVQKAVDDLNLHSYSNLPIWVNKLDMEIERILGVRLQAGLRAWTQVLLGQAEDKAEVDMDTDA---PQVSHKPGGEPKIKNVVHELRITNQVIYLNPPIEECRYKLYQEMFAWKMVVLSLPRIQSQRYQVGVHYELTEEEKFYRNALTRMPDGPVALEESYSAVMGIVSEVEQYVKVWLQYQCLWDMQAENIYNRLGEDLNKWQALLVQIRKARGTFDNAETKKEFGPVVIDYGKVQSKVNLKYDSWHKEVLSKFGQMLGSNMTEFHSQISKSRQELEQHSVDTASTSDAVTFITYVQSLKRKIKQFEKQVELYRNGQRLLEKQRFQFPPSWLYIDNIEGEWGAFNDIMRRKDSAIQQQVANLQMKIVQEDRAVESRTTDLLTDWEKTKPVTGNLRPEEALQALTIYEGKFGRLKDDREKCAKAKEALELTDTGLLSGSEERVQVALEELQDLKGVWSELSKVWEQIDQMKEQPWVSVQPRKLRQNLDALLNQLKSFPARLRQYASYEFVQRLLKGYMKINMLVIELKSEALKDRHWKQLMKRLHVNWVVSELTLGQIWDVDLQKNEAIVKDVLLVAQGEMALEEFLKQIREVWNTYELDLVNYQNKCRLIRGWDDLFNKVKEHINSVSAMKLSPYYKVFEEDALSWEDKLNRIMALFDVWIDVQRRWVYLEGIFTGSADIKHLLPVETQRFQSISTEFLALMKKVSKSPLVMDVLNIQGVQRSLERLADLLGKIQKALGEYLERERSSFPRFYFVGDEDLLEIIGNSKNVAKLQKHFKKMFAGVSSIILNEDNSVVLGISSREGEEVMFKTPVSITEHPKINEWLTLVEKEMRVTLAKLLAESVTEVEIFGKATSIDPNTYITWIDKYQAQLVVLSAQIAWSENVETALSSMGGGGDAAPLHSVLSNVEVTLNVLADSVLMEQPPLRRRKLEHLITELVHQRDVTRSLIKSKIDNAKSFEWLSQMRFYFDPKQTDVLQQLSIQMANAKFNYGFEYLGVQDKLVQTPLTDRCYLTMTQALEARLGGSPFGPAGTGKTESVKALGHQLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLSAVSQQVQCIQEALREHSNPNYDKTSAPITCELLNKQVKVSPDMAIFITMNPGYAGRSNLPDNLKKLFRSLAMTKPDRQLIAQVMLYSQGFRTAEVLANKIVPFFKLCDEQLSSQSHYDFGLRALKSVLVSAGNVKRERIQKIKREKEERGEAVDEGEIAENLPEQEILIQSVCETMVPKLVAEDIPLLFSLLSDVFPGVQYHRGEMTALREELKKVCQEMYLTYGDGEEVGG-MWVEKVLQLYQITQINHGLMMVGPSGSGKSMAWRVLLKALERLEGVEGVAHIIDPKAISKDHLYGTLDPNTREWTDGLFTHVLRKIIDSVRGELQKRQWIVFDGDVDPEWVENLNSVLDDNKLLTLPNGERLSLPPNVRIMFEVQDLKYATLATVSRCGMVWFSEDVLSTDMIFNNFLARLRSIPLDEGEDE--AQRRRKGKEDEGEEAASPMLQIQRDAATIMQPYFTSNGLVTKALEHAFQLEHIMDLTRLRCLGSLFSMLHQACRNVAQYNANHPDFPMQIEQLERYIQRYLVYAILWSLSGDSRLKMRAELGEYIRRITTVPLPTAPNIP-IIDYEVSISGEWSPWQAKVPQIEVETHKVAAPDVVVPTLDTVRHEALLYTWLAEHKPLVLCGPPGSGKTMTLFSALRALPDMEVVGLNFSSATTPELLLKTFDHYCEYRRTPNGVVLAPVQLGKWLVLFCDEINLPDMDKYGTQRVISFIRQMVEHGGFYRTSDQTWVKLERIQFVGACNPPTDPGRKPLSHRFLRHVPVVYVDYPGPASLTQIYGTFNRAMLRLIPSLRTYAEPLTAAMVEFYTMSQERFTQDTQPHYIYSPREMTRWVRGIFEALRPLETLPVEGLIRIWAHEALRLFQDRLVEDEERRWTDENIDTVALKHFPNIDREKAMSRPILYSNWLSKDYIPVDQEELRDYVKARLKVFYEEELDVPLVLFNEVLDHVLRIDRIFRQPQGHLLLIGVSGAGKTTLSRFVAWMNGLSVYQIKVHRKYTGEDFDEDLRTVLRRSGCKNEKIAFIMDESNVLDSGFLERMNTLLANGEVPGLFEGDEYATLMTQCKEGAQKEGLMLDSHEELYKWFTSQVIRNLHVVFTMNPSSEGLKDRAATSPALFNRCVLNWFGDWSTEALYQVGKEFTSKMDLEKPNYIVPDYMPVVYDKL-PQPPSHREAIVNSCVFVHQTLHQANARLAKRGGRTMAITPRHYLDFINHYANLFHEKRSELEEQQMHLNVGLRKIKETVDQVEELRRDLRIKSQELEVKNAAANDKLKKMVKDQQEAEKKKVMSQEIQEQLHKQQEVIADKQMSVKEDLDKVEPAVIEAQNAVKSIKKQHLVEVRSMANPPAAVKLALESICLLLGESTTDWKQIRSIIMRENFIPTIVNFSAEEISDAIREKMKKNYMSNPSYNYEIVNRASLACGPMVKWAIAQLNYADMLKRVEPLRNELQKLEDDAKDNQQKANEVEQMIRDLEASIARYKEEYAVLISEAQAIKADLAAVEAKVNRSTALLKSLSAERERWEKTSETFKNQMSTIAGDCLLSAAFIAYAGYFDQQMRQNLFTTWSHHLQQANIQFRTDIARTEYLSNADERLRWQASSLPADDLCTENAIMLKRFNRYPLIIDPSGQATEFIMNEYKDRKITRTSFLDDAFRKNLESALRFGNPLLVQDVESYDPVLNPVLNREVRRTGGRVLITLGDQDIDLSPSFVIFLSTRDPTVEFPPDLCSRVTFVNFTVTRSSLQSQCLNEVLKAERPDVDEKRSDLLKLQGEFQLRLRQLEKSLLQALNEVKGRILDDDTIITTLENLKREAAEVTRKVEETDIVMQEVETVSQQYLPLSTACSSIYFTMESLKQIHFLYQYSLQFFLDIYHNVLYENPNLKGVTDHTQRLSIITKDLFQVAFNRVARGMLHQDHITFAMLLARIKLKGTVGEPTYDAEFQHFLRGNEIVLSAGSTPRIQ--GLTV--EQAEAVVRLSCLPAFKDLIAKVQADEQFGIWLDSSSPEQTVPYLWSEET-----PATPIGQAIHRLLLIQAFRPDRLLAMAHMFVSTNLGESFMSIMEQPLDLTHIVGTEVKPNTPVLMCSVPGYDASGHVEDLAAEQNTQITSIAIGSAEGFNQADKAINTAVKSGRWVMLKNVHLAPGWLMQLEKKLHSLQPHACFRLFLTMEINPKVPVNLLRAGRIFVFEPPPGVKANMLRTFSSIPVSRICKSPNERARLYFLLAWFHAIIQERLRYAPLGWSKKYEFGESDLRSACDTVDTWLDDTAKGRQNISPDKIPWSALKTLMAQSIYGGRVDNEFDQRLLNTFLERLFTTRSFDSEFKLACKVDGHKDIQMPDGIRREEFVQWVELLPDTQTPSWLGLPNNAERVLLTTQGVDMISKMLKMQM-LEDEDDLAYAETEKKTRTDSTSDGRPAWMRTLHTTASNWLHLIPQTLSHLKRTVENIKDPLFRFFEREVKMGAKLLQDVRQDLADVVQVCEGKKKQTNYLRTLINELVKGILPRSWSHYTVPAGMTVIQWVSDFSERIKQLQNISLAAASGGAKELKNIHVCLGGLFVPEAYITATRQYVAQANSWSLEELCLEVNVTTSQGATLDACSFGVTGLKLQGA-TCNNNKLSLSNAISTALPLTQLRWVK-----QTNTEKKASVVTLPVYLNFTRADLIFTVDFEIATKEDPRSFYERGVAV 4642
BLAST of Cytoplasmic dynein 1 heavy chain 1 vs. UniProt/SwissProt
Match: sp|Q9JHU4|DYHC1_MOUSE (Cytoplasmic dynein 1 heavy chain 1 OS=Mus musculus OX=10090 GN=Dync1h1 PE=1 SV=2) HSP 1 Score: 6138.53 bits (15924), Expect = 0.000e+0 Identity = 2957/4618 (64.03%), Postives = 3667/4618 (79.41%), Query Frame = 3 Query: 261 ECLTKFINDNQVTTLTIQQ-TKRXXXXXXXXXXXXKISNEVNFESN---KSQTSIFIKNNQVIEADKTISSQLQVLSYCDGPPFETMHSLVCYGLLPYFXXXXXXXXXXXXXXXXXMVPSVEKKIAELEIGLLHLQQNIEIPEITLTPHPYVAHIIQEKLLQNKEARVSDFEDKFEDTQFLNQLQAGVNRWIKEIQKVTKLNRDPSTGTALQEISFWLNLEHSLDKIQEKRESLEVALTLAILKQAKRFHATTSFDTDTALSSAKIQVKDYNQLMKDFPINDLLSASQLDKISEALQQIFSHLKKVRATKYPVNRIIKLMEALSRDLTTQLMKVISNMHLMSMPYDEFEKIFTACQQVFSTWEDEYDKMQNLLRDIAKKKREEFTKFAWKMNATHKKLQTRLENIKKFRYQHEQLRQVIVRVLKP-VTKVVPSVEAGVPKDQITDKGDKSSTFLPESADTSSIDEVNAAYEIVKVIDCLDFAKEENDEWDAAIKRYEERIDRVESRIASHLRDLLGQSKNANEMFRYFSRFNALFVRPHIRGAIGEYQTQLIQRVKDDIEALHNKFKVQYASSTACKMSKVRDLPPVSGSIIWVRQILRQLNAYMKRVEDVLGKDWAQHIEGQKLKADGESFKLKLNTSELFEEWSKKVAEKSLSVAGSIFNVESTRTVVTVRDREPQKITVLKLKVNFLPDVITLAKEVRNMRALGFRTPLSIVNKAHSANQLYPFAISLIESVRTYESTCSKIEEHKMQNISLLTAGLRKDVQLCIHEGVQITWESYRLDQYVQKLAELVFSFQEKVDDLVIVIKEIDFNVKALETCSYNKQTFEEILIRIQEAVDNMSLHQFSNLAQWVSNLDSLVEQRLIVRLEAGLLEWIKVLKGXXXXXXXXXXXXXXXVNSMAKHRLGGKPQIKKLIHELRITNQQMHLYPSIEVATQDILYQMSSWQNIILNLSRIVHSRYQVGLETE-SDNQKTYKKLLSSLPNSGESLENAYAAVHNILRDANEYVKTWTNYQSLWDLQGDQLFSLIADDNTVWMNVLEEIKSMRKHFDVAETQKEFGPLVIAFGKVQSKVSMKYDNWHKEVLTKFGQNMGKMMTTLYNEVQRARNELEQQSIDSGGTNESVNFITYTQNIKRKMNTWEKQAEACRAGQNILCRDRFQFPNDWLDSENIQGEWSAFKEIMRRKQETISSQVASLQMKITEEDKIVESKTTEVLGNWEKDKPIAGDLTPEEAVNIIQILEGKFNRLKEERENVQKAKEALELTEIGVKPISEEKVTNALSELHDLKNVWNELKSIWEKIRDMKETPWLSVQPRKLRQDIENLTAQLKELPNSFKQYASFEHVRTLLKMYMKVNASIVELKSEAIKERHWRMLMRKLNVSWSLNELQLGKVWDIDLVKNEEIIREVLAIAQGEKALEEYLRQITEVWKNYVLELTNYQSKSKIIKGWDDLFNKVKEHINNVTSMKASPYFKQFEEEATAWEDRLNKINALFDVWIDVQRRWIYLDGIFAGSADIKVLLPVESQRFQSVSTEFLGLMKKVQKSPLVTDVLNIANVQRQLERLADLLGKIQKSLGEYLERQRSSFPRFYFVGDEDLLEIIGNSXXXXXXXXXXXXMFAGVHSIILSEDEKVILGMMSKEGEELRFISPVSIIEHPRINDWLTAMEKEMRVSLAKYLNVAVKEISGWRTESNIDKDKFMVWLDKYQAQIVVLAAQITWSEAVEASLASGVS------LESTMTVVHSTLNMLADTVLYEQPPVRRRKLEHLIIEYVHQRDVLRALHNDGVSSNKNFDWMSQMRFYFDPKQTDPLHQLSIHVANAKFHYGFEYLGVCDRLVQTPLTDRCYLTMTQALEARLGGSPFGPAGTGKTESVKSLGNQLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLSAVSQQIQGIQEALRELMVSKKDS----INVELLGKQVHVNPDMAIFITMNPGYAGRSNLPDNLKKLFRSLAMTQPDRQLIAQVMLYSQGFRTAEVLAGKVVPFFKLCDEQLSPQSHYDFGLRALKSVLVSAGNVKRDRIKQEKEKIVARGEEINETAIAEQLPEQEILIQSVMETMVPKLIADDIPLLYSLLTDVFPGVEYRQAEMKRLREELRKVSENKFLVYSDEPNTAGYLWVEKVLQLYQITTIHHGLMMVGPSGSGKTMACRVLLQALENIDGIEGVAHIIDPKSISKDSLYGYMDPNTREWTDGLFTHILRRIIDSVRGESNKRQWIVFDGDVDPEWVENLNSVLDDNKLLTLPNGERLAIPPNVRIMFEVQDLKYATLATVSRCGMVWFSEEVLTTGMILTHFLNELKKVQVMEGEEDFSVNQGDTGADADSKISSSPIIQLQTQVSSILAPFFTEDGLIAKCLDYSTTLEHIMDFTRLRALTSLFSMIKQSIRNMIEYNQSHSDFPLNNEQIENYVAKSLISSVVWSMSGDSKLKVREQLSQYIKNISTVDLPTVGGIKNIIDFEVNIQGTWVAWSNKVPQIEVETHKITATDVVVPTMDTVRHEALLYTWLAEHRPVLLCGPPGSGKTMTLFSALRCLPDMEVVGLNFSSATTPELMLKTFDQYCEYRKTPNGIVLAPQQLNKWLIFFCDEINLPDMDKYGTQRVISFLRQMVEHHGFYRITDMQWVSFERIQFVGACNPPTDPGRKPLSHRFLRHVPVVYVDYPGETSLKQIYSTFNRAMLRMLPSLRGYADTLTNAMVEFFLKTQERFTHDMQPHYIYSPREMTRWVRGIHEALKPLESLSVEGLVRIWAHEALRLFQDRLVEEDERHWTDDNINEVALKHFPNINKEEALKRPILYSNWLSKDYSAVTQEELRDYVKARLKVFYEEELDVPLVLFNQVLDHVLRIDRVFRQPQGHLLLIGVSGAGKTTLSRFVSWINGLSVFQVKVHNKYTAEDFDEDLRNVLRRSGCKGEKITFIMDESNVMDSSFLERMNTLLANGEVPGLFEGDELTTLMTQCKEGAIREGLMIDSQEELYKWFTQQICRNLHVVFTMNPSADGLKDKASTSPALFNRCVLNWFGDWSLEAYFQVGKEFTNRLDLERTDYKVPDTLPCIAEGLLPQNPIYRDVVVNALVFVHQTMHQANVRVQKRGGRTAAITPRHYLDLIAHYMKLSAEKRADLEEQQLHLNNGLKKIEQTVDQVEVMQRSLTKKRQELENMNEAANAKLKQMVQDQQEAEQKKTTGQALKEELAKQEQFVNEKQKTVKQELDQVEPTVNEAKQAVQNIRKKDIQEIKAMKNPPNAVKMAVESICLLLGEKTTDWQSILKVIIKDTFVTSILNFNTDDVSDNTRETMKKKYLSNPDYNFEKVNKASNACGPMVKWVLAQISYADILKRVEPLRNELTELSDAAEQNRKKSQETEDLIAQLEKSIAKYTEEYATLISQAQTIKSDLASVESKVGRSVALLGSLSSERTRWDSGSETFKAQMATINGDCLLSSAFMAYGGYFDQHMRTSLFNTWCHHLSEADILFRSDLARVEYLSNPDDRLRWQANSLPADDLCVENAIILRRYNRYPLIIDPSGQATTFLLNEYKEKKITKTSFLDDSFRKTLESALRFGTPLLVQDVESYDPILNPVLNREVRRTGGRTLITLGDQDIDLSPTFTIFLSTRDPSVEFAPDICSRVTFVNFTVTRSSLQNQCLNAVLKIERPDIDQKRSDLLKAQGEFQLKLRHLEKDLLQSLNEAQGNLLENDKIIARLETLKREAADVAKKVEETDVVMQEVESVSTEYVPLAQSCSNIYFTLEAMNQIHFLYQYSLQLMLDIFSSVLINNPELTNVKAASDRLKIITKNLFQVTYNRLARGMLHEDQITFATILARIFLKGSTPIGFLENEFQHFLRSQEATITSSDSNKQDNLGLTLHQDQIDSVKRLKKLKVFAKIEEKVKSTKDIKNWTLTVTPESNVPELWVDDNNYNDEKLSKIAKGMYNLLIIQAIRPDRLLASTQKFIASVLGDTFTESVRGTLDLASIVEVEVTACVPILLCAVQGYDPSGRVEDLASEQGKQLTGIAIGSAEGFSQAEKAINSAAKTGKWVMLKNVHLATSWLVSLEKKIHSLQAHPNFRLFLTMEITPKLPVNLLRAGRVLVFEPPPGIKANLLRTLSSINNQRMSKEPVERSRLYFLLAWLNAIVQERLRYVPLGYSKKYEFGESDFKCALDTIDTWVDGAAMGRTNLPPEKIPWVALQTLLGSCIYGGKIDNAFDQRLLNSFLGYLFTEKCFDHNFALVSDADDGSNIAFPESTKHTDILQWVHKLPDLQTPSWLGLPNSAEKVLLTNLGQSLIGNILKMQQSLEDDEELVVGQSKTK-RTIEVGDGRPAWMRQLYQSTQTWLQILPKSVTPLQRTIENIKDPMYRCFEREVNSGCNLLASVRKDLEDVAEVCKGAKKPTNHHRSMMADLAKGIIPKMWIRYAIPPGLTVIQWIQDFADRIKQLLHISDTAAKSGVIALRSIQVWLGGLFMAEAYITATRQSVAQNNKWALEELFLDVELGEGK---VDSNTCVITGLRLMGSEIVDPRTLKLSTLIYKDIDICRLKWIRVEKSQQLEGSSAKDKVCLPIYLNAARSTVLFTLYF--STTDSSYDFYKRGVAI 14048 E + KF++D QV T+ +++ T +E+ E IS +N + + KS + FIK VI+ADK +SSQL+VL+ + P+ET+HS + + P+FKSYI++ GK M PSVEKKIAELE+GLLHLQQNIEIPEI+L HP + ++ ++ + ++ +V+DF DK ED FLNQLQ+GVNRWI+EIQKVTKL+RDP++GTALQEISFWLNLE +L +IQEKRES EV LTL ILK KRFHAT SFDTDT L A V DYN LMKDFP+NDLLSA++LDKI +AL IF+HL+K+R TKYP+ R ++L+EA+SRDL++QL+KV+ LM + Y+EFEK+ AC +VF TW+DEY+K+Q LLRDI K+KREE K W++N H+KLQ RL+ ++KFR QHEQLR VIVRVL+P VT V + P+ Q K + L ++AD ++I+EVN AYE VK +D LD +KE + W+AA+KRY+ERIDRVE+RI + LRD LG +KNANEMFR FSRFNALFVRPHIRGAI EYQTQLIQRVKDDIE+LH+KFKVQY S ACKMS VRDLPPVSGSIIW +QI RQL AYMKRVEDVLGK W H+EGQKLK DG+SF++KLNT E+F++W++KV +++L V+G IF +ES R VR R VLKLKVNFLP++ITL+KEVRN++ LGFR PL+IVNKAH ANQLYPFAISLIESVRTYE TC K+EE ISLL AGL+K+VQ I EG+ + WESY+LD YVQ+LAE VF+FQEKVDDL+I+ ++ID V++LETC Y+ +TF EIL R+Q+AVD+++LH +SNL WV+ LD +E+ L VRL+AGL W +VL G+ + E D DTD H+ GG+P+IK ++HELRITNQ ++L P IE + +M +W+ ++L+L RI RYQVG+ E ++ +K Y+ L+ +P+ +LE +Y+AV I+ + +YVK W YQ LWD+Q + +++ + +D W +L +I+ R FD AET+KEFGP+VI +GKVQSKV++KYD+WHKEVL+KFGQ +G MT ++++ ++R ELEQ S+D+ T+++V FITY Q++KRK+ +EKQ E R GQ +L + RFQFP WL +NI+GEW AF +IMRRK I QVA+LQMKI +ED+ VES+TT++L +WEK KP+ G+L PEEA+ + I EGKF RLK++RE KAKEALELT+ G+ SEE+V AL EL DLK VW+EL +WE+I MKE PW+SVQPRKLRQ+++ L QLK P +QYAS+E V+ LLK YMK+N ++ELKSEA+K+RHW+ LM++L+V+W ++EL LG++WD+DL KNE ++++VL +AQGE ALEE+L+QI EVW Y L+L NYQ+K ++I+GWDDLFNKVKEHIN+V++MK SPY+K FEE+A +WED+LN+I ALFDVWIDVQRRW+YL+GIF GSADIK LLPVE+QRFQS+STEFL LMKKV KSPLV DVLNI VQR LERLADLLGKIQK+LGEYLER+RSSFPRFYFVGDEDLLEIIGNSK++ KLQKHFKKMFAGV SIIL+ED V+LG+ S+EGEE+ F +PVSI EHP+IN+WLT +EKEMRV+LAK L +V E+ + ++ID + ++ W+DKYQAQ+VVL+AQI WSE VE +L++ L+S ++ V TLN+LAD+VL EQPP+RRRKLEHLI E VHQRDV R+L + + K+F+W+SQMRFYFDPKQTD L QLSI +ANAKF+YGFEYLGV D+LVQTPLTDRCYLTMTQALEARLGGSPFGPAGTGKTESVK+LG+QLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLSAVSQQ+Q IQEALRE D I ELL KQV V+PDMAIFITMNPGYAGRSNLPDNLKKLFRSLAMT+PDRQLIAQVMLYSQGFRTAEVLA K+VPFFKLCDEQLS QSHYDFGLRALKSVLVSAGNVKR+RI++ K + RGE ++E IAE LPEQEILIQSV ETMVPKL+A+DIPLL+SLL+DVFPGV+Y + EM LREEL+KV + +L Y D G +WVEKVLQLYQIT I+HGLMMVGPSGSGK+MA RVLL+ALE ++G+EGVAHIIDPK+ISKD LYG +DPNTREWTDGLFTH+LR+IID+VRGE KRQWIVFDGDVDPEWVENLNSVLDDNKLLTLPNGERL++PPNVRIMFEVQDLKYATLATVSRCGMVWFSE+VL+T MI +FL L+ + + EGE++ + G + + + ++SP++Q+Q ++I+ P+FT +GL+ K L+++ LEHIMD TRLR L SLFSM+ Q+ RN+ +YN +H DFP+ EQ+E Y+ + L+ +++WS+SGDS+LK+R +L +YI+ I+TV LPT + IID+EV+I G W W KVPQIEVETHK+ A DVVVPT+DTVRHEALLYTWLAEH+P++LCGPPGSGKTMTLFSALR LPDMEVVGLNFSSATTPEL+LKTFD YCEYR+TPNG+VLAP QL KWL+ FCDEINLPDMDKYGTQRVISF+RQMVEH GFYR +D WV ERIQFVGACNPPTDPGRKPLSHRFLRHVPVVYVDYPG SL QIY TFNRAMLR++PSLR YA+ LT AMVEF+ +QERFT D QPHYIYSPREMTRWVRGI EAL+PLE+L VEGL+RIWAHEALRLFQDRLVE++ER WTD+NI+ VALKHFPNI+KE+A+ RPILYSNWLSKDY V QEELRDYVKARLKVFYEEELDVPLVLFN+VLDHVLRIDR+FRQPQGHLLLIGVSGAGKTTLSRFV+W+NGLSV+Q+KVH KYT EDFDEDLR VLRRSGCK EKI FIMDESNV+DS FLERMNTLLANGEVPGLFEGDE TLMTQCKEGA +EGLM+DS EELYKWFT Q+ RNLHVVFTMNPS++GLKD+A+TSPALFNRCVLNWFGDWS EA +QVGKEFT+++DLE+ +Y VPD +P + + L PQ P +R+ +VN+ VFVHQT+HQAN R+ KRGGRT AITPRHYLD I HY L EKR++LEEQQ+HLN GL+KI++TVDQVE ++R L K QELE N AAN KLK+MV+DQQEAE+KK Q ++E+L KQ++ + +KQ +VK++LD+VEP V EA+ AV++I+K+ + E+++M NPP AVK+A+ESICLLLGE TTDW+ I +I+++ F+ +I+NF+ +++SD RE MKK Y+SNP YN+E VN+AS ACGPMVKW +AQ++YAD+LKRVEPLRNEL +L D A+ N++K+ E E +I LE SIA+Y EEYA LIS+AQ IK+DLA+VE+KV RS ALL SLS+ER RW+ SETFK QM+TI GDCLLS+AF+AY GYFDQ MR +LF TW HHL +A+I FR+D+AR EYLSN D+RLRWQA+SLPADDLC ENAI+L+R+NRYPLIIDPSGQAT F++NEYK++KIT+TSFLDD+FRK LESALRFG PLLVQDVESYDP+LNPVLNREVRRTGGR LITLGDQDIDLSP+F IFLSTRDP+VEF PD+CSRVTFVNFTVTRSSLQ+QCLN VLK ERPD+D+KRSDLLK QGEFQL+LR LEK LLQ+LNE +G +L++D II LE LKREAA+V +KVEETD+VMQEVE+VS +Y+PL+ +CS+IYFT+E++ Q+HFLYQYSLQ LDI+ +VL NP L + RL IITK+LFQV +NR+ARGMLH+D ITFA +LARI LKG+ + EFQHFLR +E +++ + K GLT+ +Q ++V RL L F + KV++ + W + +PE VP LW ++ + I + ++ LL+IQA RPDRLLA F+++ LG++F + LDL IV EV P+L+C+V GYD SG VEDLA+EQ Q+T IAIGSAEGF+QA+KAIN+A K+G+WVMLKNVHLA WL+ LEKK+HSLQ H FRLFLTMEI PK+PVNLLRAGR+ VFEPPPG+KAN+LRT SSI R+ K P ER+RLYFLLAW +AI+QERLRY PLG+SKKYEFGESD + A DT+DTW+D A GR N+ P+KIPW AL+TL+ IYGG++DN FDQRLLN+FL LFT + FD F L D +I P+ + + +QWV LPD QTPSWLGLPN+AE+VLLT G +I +LKMQ LED+++L +++ K RT DGRPAWMR L+ + WL ++P++++PL+RT+ENIKDP++R FEREV G LL VR+DL DV +VC+G KK TN+ R+++ +L KGI+P+ W Y +P G+TVIQW+ DF++RIKQL +IS AA G L++I V LGGLF+ EAYITATRQ VAQ N W+LEEL L+V + + +D+ + +TGL+L G+ + + L LS I + + +L+W++ Q V LP+YLN R+ ++FT+ F +T + FY+RGVA+ Sbjct: 61 EQMRKFLSDPQVHTVLVERSTLKEDVGDEGEEEKEFISYNINIDIHYGVKSNSLAFIKRAPVIDADKPVSSQLRVLTLSEDSPYETLHSFISNAVAPFFKSYIRESGKADRDGDK-MAPSVEKKIAELEMGLLHLQQNIEIPEISLPIHPIITNVAKQCYERGEKPKVTDFGDKVEDPTFLNQLQSGVNRWIREIQKVTKLDRDPASGTALQEISFWLNLERALYRIQEKRESPEVLLTLDILKHGKRFHATVSFDTDTGLKQALETVNDYNPLMKDFPLNDLLSATELDKIRQALVAIFTHLRKIRNTKYPIQRALRLVEAISRDLSSQLLKVLGTRKLMHVAYEEFEKVMVACFEVFQTWDDEYEKLQVLLRDIVKRKREENLKMVWRINPAHRKLQARLDQMRKFRRQHEQLRAVIVRVLRPQVTAVAQQNQGEAPEPQDM----KVAEVLFDAADANAIEEVNLAYENVKEVDGLDVSKEGTEAWEAAMKRYDERIDRVETRITARLRDQLGTAKNANEMFRIFSRFNALFVRPHIRGAIREYQTQLIQRVKDDIESLHDKFKVQYPQSQACKMSHVRDLPPVSGSIIWAKQIDRQLTAYMKRVEDVLGKGWENHVEGQKLKQDGDSFRMKLNTQEIFDDWARKVQQRNLGVSGRIFTIESAR----VRGRTG---NVLKLKVNFLPEIITLSKEVRNLKWLGFRVPLAIVNKAHQANQLYPFAISLIESVRTYERTCEKVEERN--TISLLVAGLKKEVQALIAEGIALVWESYKLDPYVQRLAETVFNFQEKVDDLLIIEEKIDLEVRSLETCMYDHKTFSEILNRVQKAVDDLNLHSYSNLPIWVNKLDMEIERILGVRLQAGLRAWTQVLLGQAEDKAEVDMDTDA---PQVSHKPGGEPKIKNVVHELRITNQVIYLNPPIEECRYKLYQEMFAWKMVVLSLPRIQSQRYQVGVHYELTEEEKFYRNALTRMPDGPVALEESYSAVMGIVTEVEQYVKVWLQYQCLWDMQAENIYNRLGEDLNKWQALLVQIRKARGTFDNAETKKEFGPVVIDYGKVQSKVNLKYDSWHKEVLSKFGQMLGSNMTEFHSQISKSRQELEQHSVDTASTSDAVTFITYVQSLKRKIKQFEKQVELYRNGQRLLEKQRFQFPPSWLYIDNIEGEWGAFNDIMRRKDSAIQQQVANLQMKIVQEDRAVESRTTDLLTDWEKTKPVTGNLRPEEALQALTIYEGKFGRLKDDREKCAKAKEALELTDTGLLSGSEERVQVALEELQDLKGVWSELSKVWEQIDQMKEQPWVSVQPRKLRQNLDGLLNQLKNFPARLRQYASYEFVQRLLKGYMKINMLVIELKSEALKDRHWKQLMKRLHVNWVVSELTLGQIWDVDLQKNEAVVKDVLLVAQGEMALEEFLKQIREVWNTYELDLVNYQNKCRLIRGWDDLFNKVKEHINSVSAMKLSPYYKVFEEDALSWEDKLNRIMALFDVWIDVQRRWVYLEGIFTGSADIKHLLPVETQRFQSISTEFLALMKKVSKSPLVMDVLNIQGVQRSLERLADLLGKIQKALGEYLERERSSFPRFYFVGDEDLLEIIGNSKNVAKLQKHFKKMFAGVSSIILNEDNSVVLGISSREGEEVMFKTPVSITEHPKINEWLTLVEKEMRVTLAKLLAESVTEVEIFGKATSIDPNTYITWIDKYQAQLVVLSAQIAWSENVENALSNVGGGGDVGPLQSVLSNVEVTLNVLADSVLMEQPPLRRRKLEHLITELVHQRDVTRSLIKSKIDNAKSFEWLSQMRFYFDPKQTDVLQQLSIQMANAKFNYGFEYLGVQDKLVQTPLTDRCYLTMTQALEARLGGSPFGPAGTGKTESVKALGHQLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLSAVSQQVQCIQEALREHSNPNYDKTSAPITCELLNKQVKVSPDMAIFITMNPGYAGRSNLPDNLKKLFRSLAMTKPDRQLIAQVMLYSQGFRTAEVLANKIVPFFKLCDEQLSSQSHYDFGLRALKSVLVSAGNVKRERIQKIKREKEERGEAVDEGEIAENLPEQEILIQSVCETMVPKLVAEDIPLLFSLLSDVFPGVQYHRGEMTALREELKKVCQEMYLTYGDGEEVGG-MWVEKVLQLYQITQINHGLMMVGPSGSGKSMAWRVLLKALERLEGVEGVAHIIDPKAISKDHLYGTLDPNTREWTDGLFTHVLRKIIDNVRGELQKRQWIVFDGDVDPEWVENLNSVLDDNKLLTLPNGERLSLPPNVRIMFEVQDLKYATLATVSRCGMVWFSEDVLSTDMIFNNFLARLRSIPLDEGEDE--AQRRRKGKEDEGEEAASPMLQIQRDAATIMQPYFTSNGLVTKALEHAFKLEHIMDLTRLRCLGSLFSMLHQACRNVAQYNANHPDFPMQIEQLERYIQRYLVYAILWSLSGDSRLKMRAELGEYIRRITTVPLPTAPNVP-IIDYEVSISGEWSPWQAKVPQIEVETHKVAAPDVVVPTLDTVRHEALLYTWLAEHKPLVLCGPPGSGKTMTLFSALRALPDMEVVGLNFSSATTPELLLKTFDHYCEYRRTPNGVVLAPVQLGKWLVLFCDEINLPDMDKYGTQRVISFIRQMVEHGGFYRTSDQTWVKLERIQFVGACNPPTDPGRKPLSHRFLRHVPVVYVDYPGPASLTQIYGTFNRAMLRLIPSLRTYAEPLTAAMVEFYTMSQERFTQDTQPHYIYSPREMTRWVRGIFEALRPLETLPVEGLIRIWAHEALRLFQDRLVEDEERRWTDENIDMVALKHFPNIDKEKAMSRPILYSNWLSKDYIPVDQEELRDYVKARLKVFYEEELDVPLVLFNEVLDHVLRIDRIFRQPQGHLLLIGVSGAGKTTLSRFVAWMNGLSVYQIKVHRKYTGEDFDEDLRTVLRRSGCKNEKIAFIMDESNVLDSGFLERMNTLLANGEVPGLFEGDEYATLMTQCKEGAQKEGLMLDSHEELYKWFTSQVIRNLHVVFTMNPSSEGLKDRAATSPALFNRCVLNWFGDWSTEALYQVGKEFTSKMDLEKPNYIVPDYMPVVYDKL-PQPPTHREAIVNSCVFVHQTLHQANARLAKRGGRTMAITPRHYLDFINHYANLFHEKRSELEEQQMHLNVGLRKIKETVDQVEELRRDLRIKSQELEVKNAAANDKLKKMVKDQQEAEKKKVMSQEIQEQLHKQQEVIADKQMSVKEDLDKVEPAVIEAQNAVKSIKKQHLVEVRSMANPPAAVKLALESICLLLGESTTDWKQIRSIIMRENFIPTIVNFSAEEISDAIREKMKKNYMSNPSYNYEIVNRASLACGPMVKWAIAQLNYADMLKRVEPLRNELQKLEDDAKDNQQKANEVEQMIRDLEASIARYKEEYAVLISEAQAIKADLAAVEAKVNRSTALLKSLSAERERWEKTSETFKNQMSTIAGDCLLSAAFIAYAGYFDQQMRQNLFTTWSHHLQQANIQFRTDIARTEYLSNADERLRWQASSLPADDLCTENAIMLKRFNRYPLIIDPSGQATEFIMNEYKDRKITRTSFLDDAFRKNLESALRFGNPLLVQDVESYDPVLNPVLNREVRRTGGRVLITLGDQDIDLSPSFVIFLSTRDPTVEFPPDLCSRVTFVNFTVTRSSLQSQCLNEVLKAERPDVDEKRSDLLKLQGEFQLRLRQLEKSLLQALNEVKGRILDDDTIITTLENLKREAAEVTRKVEETDIVMQEVETVSQQYLPLSTACSSIYFTMESLKQVHFLYQYSLQFFLDIYHNVLYENPNLKGATDHTQRLSIITKDLFQVAFNRVARGMLHQDHITFAMLLARIKLKGTVGEPTYDAEFQHFLRGKEIVLSAGSTPKIQ--GLTV--EQAEAVVRLSCLPAFKDLIAKVQADEQFGIWLDSSSPEQTVPYLWSEET-----PTTPIGQAIHRLLLIQAFRPDRLLAMAHMFVSTNLGESFMSIMEQPLDLTHIVGTEVKPNTPVLMCSVPGYDASGHVEDLAAEQNTQITSIAIGSAEGFNQADKAINTAVKSGRWVMLKNVHLAPGWLMQLEKKLHSLQPHACFRLFLTMEINPKVPVNLLRAGRIFVFEPPPGVKANMLRTFSSIPVSRICKSPNERARLYFLLAWFHAIIQERLRYAPLGWSKKYEFGESDLRSACDTVDTWLDDTAKGRQNISPDKIPWSALKTLMAQSIYGGRVDNEFDQRLLNTFLERLFTTRSFDSEFKLACKVDGHKDIQMPDGIRREEFVQWVELLPDAQTPSWLGLPNNAERVLLTTQGVDMISKMLKMQM-LEDEDDLAYAETEKKARTDSTSDGRPAWMRTLHTTASNWLHLIPQTLSPLKRTVENIKDPLFRFFEREVKMGAKLLQDVRQDLADVVQVCEGKKKQTNYLRTLINELVKGILPRSWSHYTVPAGMTVIQWVSDFSERIKQLQNISQAAASGGAKELKNIHVCLGGLFVPEAYITATRQYVAQANSWSLEELCLEVNVTASQSATLDACSFGVTGLKLQGATCSNNK-LSLSNAISTVLPLTQLRWVK-----QTSAEKKASVVTLPVYLNFTRADLIFTVDFEIATKEDPRSFYERGVAV 4640
BLAST of Cytoplasmic dynein 1 heavy chain 1 vs. UniProt/SwissProt
Match: sp|P38650|DYHC1_RAT (Cytoplasmic dynein 1 heavy chain 1 OS=Rattus norvegicus OX=10116 GN=Dync1h1 PE=1 SV=1) HSP 1 Score: 6126.2 bits (15892), Expect = 0.000e+0 Identity = 2953/4618 (63.95%), Postives = 3662/4618 (79.30%), Query Frame = 3 Query: 261 ECLTKFINDNQVTTLTIQQ-TKRXXXXXXXXXXXXKISNEVNFESN---KSQTSIFIKNNQVIEADKTISSQLQVLSYCDGPPFETMHSLVCYGLLPYFXXXXXXXXXXXXXXXXXMVPSVEKKIAELEIGLLHLQQNIEIPEITLTPHPYVAHIIQEKLLQNKEARVSDFEDKFEDTQFLNQLQAGVNRWIKEIQKVTKLNRDPSTGTALQEISFWLNLEHSLDKIQEKRESLEVALTLAILKQAKRFHATTSFDTDTALSSAKIQVKDYNQLMKDFPINDLLSASQLDKISEALQQIFSHLKKVRATKYPVNRIIKLMEALSRDLTTQLMKVISNMHLMSMPYDEFEKIFTACQQVFSTWEDEYDKMQNLLRDIAKKKREEFTKFAWKMNATHKKLQTRLENIKKFRYQHEQLRQVIVRVLKP-VTKVVPSVEAGVPKDQITDKGDKSSTFLPESADTSSIDEVNAAYEIVKVIDCLDFAKEENDEWDAAIKRYEERIDRVESRIASHLRDLLGQSKNANEMFRYFSRFNALFVRPHIRGAIGEYQTQLIQRVKDDIEALHNKFKVQYASSTACKMSKVRDLPPVSGSIIWVRQILRQLNAYMKRVEDVLGKDWAQHIEGQKLKADGESFKLKLNTSELFEEWSKKVAEKSLSVAGSIFNVESTRTVVTVRDREPQKITVLKLKVNFLPDVITLAKEVRNMRALGFRTPLSIVNKAHSANQLYPFAISLIESVRTYESTCSKIEEHKMQNISLLTAGLRKDVQLCIHEGVQITWESYRLDQYVQKLAELVFSFQEKVDDLVIVIKEIDFNVKALETCSYNKQTFEEILIRIQEAVDNMSLHQFSNLAQWVSNLDSLVEQRLIVRLEAGLLEWIKVLKGXXXXXXXXXXXXXXXVNSMAKHRLGGKPQIKKLIHELRITNQQMHLYPSIEVATQDILYQMSSWQNIILNLSRIVHSRYQVGLETE-SDNQKTYKKLLSSLPNSGESLENAYAAVHNILRDANEYVKTWTNYQSLWDLQGDQLFSLIADDNTVWMNVLEEIKSMRKHFDVAETQKEFGPLVIAFGKVQSKVSMKYDNWHKEVLTKFGQNMGKMMTTLYNEVQRARNELEQQSIDSGGTNESVNFITYTQNIKRKMNTWEKQAEACRAGQNILCRDRFQFPNDWLDSENIQGEWSAFKEIMRRKQETISSQVASLQMKITEEDKIVESKTTEVLGNWEKDKPIAGDLTPEEAVNIIQILEGKFNRLKEERENVQKAKEALELTEIGVKPISEEKVTNALSELHDLKNVWNELKSIWEKIRDMKETPWLSVQPRKLRQDIENLTAQLKELPNSFKQYASFEHVRTLLKMYMKVNASIVELKSEAIKERHWRMLMRKLNVSWSLNELQLGKVWDIDLVKNEEIIREVLAIAQGEKALEEYLRQITEVWKNYVLELTNYQSKSKIIKGWDDLFNKVKEHINNVTSMKASPYFKQFEEEATAWEDRLNKINALFDVWIDVQRRWIYLDGIFAGSADIKVLLPVESQRFQSVSTEFLGLMKKVQKSPLVTDVLNIANVQRQLERLADLLGKIQKSLGEYLERQRSSFPRFYFVGDEDLLEIIGNSXXXXXXXXXXXXMFAGVHSIILSEDEKVILGMMSKEGEELRFISPVSIIEHPRINDWLTAMEKEMRVSLAKYLNVAVKEISGWRTESNIDKDKFMVWLDKYQAQIVVLAAQITWSEAVEASLASGVS------LESTMTVVHSTLNMLADTVLYEQPPVRRRKLEHLIIEYVHQRDVLRALHNDGVSSNKNFDWMSQMRFYFDPKQTDPLHQLSIHVANAKFHYGFEYLGVCDRLVQTPLTDRCYLTMTQALEARLGGSPFGPAGTGKTESVKSLGNQLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLSAVSQQIQGIQEALRELMVSKKDS----INVELLGKQVHVNPDMAIFITMNPGYAGRSNLPDNLKKLFRSLAMTQPDRQLIAQVMLYSQGFRTAEVLAGKVVPFFKLCDEQLSPQSHYDFGLRALKSVLVSAGNVKRDRIKQEKEKIVARGEEINETAIAEQLPEQEILIQSVMETMVPKLIADDIPLLYSLLTDVFPGVEYRQAEMKRLREELRKVSENKFLVYSDEPNTAGYLWVEKVLQLYQITTIHHGLMMVGPSGSGKTMACRVLLQALENIDGIEGVAHIIDPKSISKDSLYGYMDPNTREWTDGLFTHILRRIIDSVRGESNKRQWIVFDGDVDPEWVENLNSVLDDNKLLTLPNGERLAIPPNVRIMFEVQDLKYATLATVSRCGMVWFSEEVLTTGMILTHFLNELKKVQVMEGEEDFSVNQGDTGADADSKISSSPIIQLQTQVSSILAPFFTEDGLIAKCLDYSTTLEHIMDFTRLRALTSLFSMIKQSIRNMIEYNQSHSDFPLNNEQIENYVAKSLISSVVWSMSGDSKLKVREQLSQYIKNISTVDLPTVGGIKNIIDFEVNIQGTWVAWSNKVPQIEVETHKITATDVVVPTMDTVRHEALLYTWLAEHRPVLLCGPPGSGKTMTLFSALRCLPDMEVVGLNFSSATTPELMLKTFDQYCEYRKTPNGIVLAPQQLNKWLIFFCDEINLPDMDKYGTQRVISFLRQMVEHHGFYRITDMQWVSFERIQFVGACNPPTDPGRKPLSHRFLRHVPVVYVDYPGETSLKQIYSTFNRAMLRMLPSLRGYADTLTNAMVEFFLKTQERFTHDMQPHYIYSPREMTRWVRGIHEALKPLESLSVEGLVRIWAHEALRLFQDRLVEEDERHWTDDNINEVALKHFPNINKEEALKRPILYSNWLSKDYSAVTQEELRDYVKARLKVFYEEELDVPLVLFNQVLDHVLRIDRVFRQPQGHLLLIGVSGAGKTTLSRFVSWINGLSVFQVKVHNKYTAEDFDEDLRNVLRRSGCKGEKITFIMDESNVMDSSFLERMNTLLANGEVPGLFEGDELTTLMTQCKEGAIREGLMIDSQEELYKWFTQQICRNLHVVFTMNPSADGLKDKASTSPALFNRCVLNWFGDWSLEAYFQVGKEFTNRLDLERTDYKVPDTLPCIAEGLLPQNPIYRDVVVNALVFVHQTMHQANVRVQKRGGRTAAITPRHYLDLIAHYMKLSAEKRADLEEQQLHLNNGLKKIEQTVDQVEVMQRSLTKKRQELENMNEAANAKLKQMVQDQQEAEQKKTTGQALKEELAKQEQFVNEKQKTVKQELDQVEPTVNEAKQAVQNIRKKDIQEIKAMKNPPNAVKMAVESICLLLGEKTTDWQSILKVIIKDTFVTSILNFNTDDVSDNTRETMKKKYLSNPDYNFEKVNKASNACGPMVKWVLAQISYADILKRVEPLRNELTELSDAAEQNRKKSQETEDLIAQLEKSIAKYTEEYATLISQAQTIKSDLASVESKVGRSVALLGSLSSERTRWDSGSETFKAQMATINGDCLLSSAFMAYGGYFDQHMRTSLFNTWCHHLSEADILFRSDLARVEYLSNPDDRLRWQANSLPADDLCVENAIILRRYNRYPLIIDPSGQATTFLLNEYKEKKITKTSFLDDSFRKTLESALRFGTPLLVQDVESYDPILNPVLNREVRRTGGRTLITLGDQDIDLSPTFTIFLSTRDPSVEFAPDICSRVTFVNFTVTRSSLQNQCLNAVLKIERPDIDQKRSDLLKAQGEFQLKLRHLEKDLLQSLNEAQGNLLENDKIIARLETLKREAADVAKKVEETDVVMQEVESVSTEYVPLAQSCSNIYFTLEAMNQIHFLYQYSLQLMLDIFSSVLINNPELTNVKAASDRLKIITKNLFQVTYNRLARGMLHEDQITFATILARIFLKGSTPIGFLENEFQHFLRSQEATITSSDSNKQDNLGLTLHQDQIDSVKRLKKLKVFAKIEEKVKSTKDIKNWTLTVTPESNVPELWVDDNNYNDEKLSKIAKGMYNLLIIQAIRPDRLLASTQKFIASVLGDTFTESVRGTLDLASIVEVEVTACVPILLCAVQGYDPSGRVEDLASEQGKQLTGIAIGSAEGFSQAEKAINSAAKTGKWVMLKNVHLATSWLVSLEKKIHSLQAHPNFRLFLTMEITPKLPVNLLRAGRVLVFEPPPGIKANLLRTLSSINNQRMSKEPVERSRLYFLLAWLNAIVQERLRYVPLGYSKKYEFGESDFKCALDTIDTWVDGAAMGRTNLPPEKIPWVALQTLLGSCIYGGKIDNAFDQRLLNSFLGYLFTEKCFDHNFALVSDADDGSNIAFPESTKHTDILQWVHKLPDLQTPSWLGLPNSAEKVLLTNLGQSLIGNILKMQQSLEDDEELVVGQSKTK-RTIEVGDGRPAWMRQLYQSTQTWLQILPKSVTPLQRTIENIKDPMYRCFEREVNSGCNLLASVRKDLEDVAEVCKGAKKPTNHHRSMMADLAKGIIPKMWIRYAIPPGLTVIQWIQDFADRIKQLLHISDTAAKSGVIALRSIQVWLGGLFMAEAYITATRQSVAQNNKWALEELFLDVELGEGK---VDSNTCVITGLRLMGSEIVDPRTLKLSTLIYKDIDICRLKWIRVEKSQQLEGSSAKDKVCLPIYLNAARSTVLFTLYF--STTDSSYDFYKRGVAI 14048 E + KF++D QV T+ +++ T +E+ E IS +N + + KS + FIK VI+ADK +SSQL+VL+ + P+ET+HS + + P+FKSYI++ GK M PSVEKKIAELE+GLLHLQQNIEIPEI+L HP + ++ ++ + ++ +V+DF DK ED FLNQLQ+GVNRWI+EIQKVTKL+RDP++GTALQEISFWLNLE +L +IQEKRES EV LTL ILK KRFHAT SFDTDT L A V DYN LMKDFP+NDLLSA++LDKI +AL IF+HL+K+R TKYP+ R ++L+EA+SRDL++QL+KV+ LM + Y+EFEK+ AC +VF TW+DEY+K+Q LLRDI K+KREE K W++N H+KLQ RL+ ++KFR QHEQLR VIVRVL+P VT V + P+ Q K + L ++AD ++I+EVN AYE VK +D LD +KE + W+AA+KRY+ERIDRVE+RI + LRD LG +KNANEMFR FSRFNALFVRPHIRGAI EYQTQLIQRVKDDIE+LH+KFKVQY S ACKMS VRDLPPVSGSIIW +QI RQL AYMKRVEDVLGK W H+EGQKLK DG+SF++KLNT E+F++W++KV +++L V+G IF +ES R VR R VLKLKVNFLP++ITL+KEVRN++ LGFR PL+IVNKAH ANQLYPFAISLIESVRTYE TC K+EE ISLL AGL+K+VQ I EG+ + WESY+LD YVQ+LAE VF+FQEKVDDL+I+ ++ID V++LETC Y+ +TF EIL R+Q+AVD+++LH +SNL WV+ LD +E+ L VRL+AGL W +VL G+ + E D DTD H+ GG+P+IK ++HELRITNQ ++L P IE + +M +W+ I+L+L RI RYQVG+ E ++ +K Y+ L+ + +LE +Y+AV I+ + +YVK W YQ LWD+Q + +++ + +D + W +L +I+ R FD AET+KEFGP+VI +GKVQSKV++KYD+WHKEVL+KFGQ +G MT ++++ ++R ELEQ S+D+ T+++V FITY Q++KRK+ +EKQ E R GQ +L + RFQFP WL +NI+GEW AF +IMRRK I QVA+LQMKI +ED+ VES+TT++L +WEK KP+ G+L PEEA+ + I EGKF RLK++RE KAKEALELT+ G+ SEE+V AL EL DLK VW+EL +WE+I MKE PW+SVQPRKLRQ+++ L QLK P +QYAS+E V+ LLK YMK+N ++ELKSEA+K+RHW+ LM++L+V+W ++EL LG++WD+DL KNE I+++VL +AQGE ALEE+L+QI EVW Y L+L NYQ+K ++I+GWDDLFNKVKEHIN+V++MK SPY+K FEE+A +WED+LN+I ALFDVWIDVQRRW+YL+GIF GSADIK LLPVE+QRFQS+STEFL LMKKV KSPLV DVLNI VQR LERLADLLGKIQK+LGEYLER+RSSFPRFYFVGDEDLLEIIGNSK++ KLQKHFKKMFAGV SIIL+ED V+LG+ S+EGEE+ F +PVSI EHP+IN+WLT +EKEMRV+LAK L +V E+ + ++ID + ++ W+DKYQAQ+VVL+AQI WSE VE +L++ L+S ++ V TLN+LAD+VL EQPP+RRRKLEHLI E VHQRDV R+L + + K+F+W+SQMRFYFDPKQTD L QLSI +ANAKF+YGFEYLGV D+LVQTPLTDRCYLTMTQALEARLGGSPFGPAGTGKTESVK+LG+QLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLSAVSQQ+Q IQEALRE D I ELL KQV V+PDMAIFITMNPGYAGRSNLPDNLKKLFRSLAMT+PDRQLIAQVMLYSQGFRTAEVLA K+VPFFKLCDEQLS QSHYDFGLRALKSVLVS GNVKR+RI++ K + RGE ++E IAE LPEQEILIQS ETMVPKL+A+DIPLL+SLL+DVFPGV+Y + EM LREEL+KV + +L Y D G +WVEKVLQLYQIT I+HGLMMVGPSGSGK+MA RVLL+ALE ++G+EGVAHIIDPK+ISKD LYG +DPNTREWTDGLFTH+LR+IID+VRGE KRQWIVFDGDVDPEWVENLNSVLDDNKLLTLPNGERL++PPNVRIMFEVQDLKYATLATVSRCGMVWFSE++L+T MI +FL L+ + + EGE++ + G + + + ++SP++Q+Q ++I+ P+FT +GL+ K L+++ LEHIMD TRLR L SLFSM+ Q RN+ +YN +H DFP+ EQ+E Y+ + L+ +++WS+SGDS+LK+R +L +YI+ I+TV LPT I IID+EV+I G W W KVPQIEVETHK+ A DVVVPT+DTVRHEALLYTWLAEH+P++LCGPPGSGKTMTLFSALR LPDMEVVGLNFSSATTPEL+LKTFD YCEYR+TPNG+VLAP QL KWL+ FCDEINLPDMDKYGTQRVISF+RQMVEH GFYR +D WV ERIQFVGACNPPTDPGRKPLSHRFLRHVPVVYVDYPG SL QIY TFNRAMLR++PSLR YA+ LT AMVEF+ +QERFT D QPHYIYSPREMTRWVRGI EAL+PLE+L VEGL+RIWAHEALRLFQDRLVE++ER WTD+NI+ VALKHFPNI+KE+A+ RPILYSNWLSKDY V QEELRDYVKARLKVFYEEELDVPLVLFN+VLDHVLRIDR+FRQPQGHLLLIGVSGAGKTTLSRFV+W+NGLSV+Q+KVH KYT EDFDEDLR VLRRSGCK EKI FIMDESNV+DS FLERMNTLLANGEVPGLFEGDE TLMTQCKEGA +EGLM+DS EELYKWFT Q+ RNLHVVFTMNPS++GLKD+A+TSPALFNRCVLNWFGDWS EA +QVGKEFT+++DLE+ +Y VPD +P + + L PQ P +R+ +VN+ VFVHQT+HQAN R+ KRGGRT AITPRHYLD I HY L EKR++LEEQQ+HLN GL+KI++TVDQVE ++R+L K QELE N AAN KLK+MV+DQQEAE+KK Q ++E+L KQ++ + +KQ +VK++LD+VEP V EA+ AV++I+K+ + E+++M NPP AVK+A+ESICLLLGE TTDW+ I +I+++ F+ +I+NF+ +++SD RE MKK Y+SNP YN+E VN+AS ACGPMVKW +AQ++YAD+LKRVEPLRNEL +L D A+ N++K+ E E +I LE SIA+Y EEYA LIS+AQ IK+DLA+VE+KV RS ALL SLS+ER RW+ SETFK QM+TI GDCLLS+AF+AY GYFDQ MR +LF TW HHL +A+I FR+D+AR EYLSN D+RLRWQA+SLPADDLC ENAI+L+R+NRYPLIIDPSGQAT F++NEYK++KIT+TSFLDD+FRK LESALRFG PLLVQDVESYDP+LNPVLNREVRRTGGR LITLGDQDIDLSP+F IFLSTRDP+VEF PD+CSRVTFVNFTVTRSSLQ+QCLN VLK ERPD+D+KRSDLLK QGEFQL+LR LEK LLQ+LNE +G +L++D II LE LKREAA+V +KVEETD+VMQEVE+VS +Y+PL+ +CS+IYFT+E++ Q+HFLYQYSLQ LDI+ +VL NP L + RL +ITK+LFQV +NR+ARGMLH+D ITFA +LARI LKG+ + EFQHFLR +E +++ + K GLT+ +Q ++V RL L F + KV++ + W + +PE VP LW ++ + I + ++ LL+IQA RPDRLLA F+++ LG++F + LDL IV EV P+L+C+V GYD SG VEDLA+EQ Q+T IAIGSAEGF+QA+KAIN+A K+G+WVMLKNVHLA WL+ LEKK+HSLQ H FRLFLTMEI P++PVNLLRAGR+ VFEPPPG+KAN+LRT SSI RM K P ER+RLYFLLAW +A++QERLRY PLG+SKKYEFGESD + A DT+DTW+D A GR N+ P+KIPW AL+TL+ IYGG++DN FDQRLLN+FL LFT + FD F L D +I P+ + + +QWV LPD QTPSWLGLPN+AE+VLLT G +I +LKMQ LED+++L +++ K RT DGRPAWMR L+ + WL ++P++++PL+RT+ENIKDP++R FEREV G LL VR+DL DV +VC+G KK TN+ R+++ +L KGI+P+ W Y +P G+TVIQW+ DF++RIKQL +IS AA G L++I V LG LF+ EAYITATRQ VAQ N W+LEEL L+V + + +D+ + +TGL+L G+ + + L LS I + + +L+W +Q V LP+YLN R+ ++FT+ F +T + FY+RGVA+ Sbjct: 61 EQMRKFLSDPQVHTVLVERSTLKEDVGDEGEEEKEFISYNINIDIHYGVKSNSLAFIKRAPVIDADKPVSSQLRVLTLSEDSPYETLHSFISNAVAPFFKSYIRESGKADRDGDK-MAPSVEKKIAELEMGLLHLQQNIEIPEISLPIHPIITNVAKQCYERGEKPKVTDFGDKVEDPTFLNQLQSGVNRWIREIQKVTKLDRDPASGTALQEISFWLNLERALYRIQEKRESPEVLLTLDILKHGKRFHATVSFDTDTGLKQALETVNDYNPLMKDFPLNDLLSATELDKIRQALVAIFTHLRKIRNTKYPIQRALRLVEAISRDLSSQLLKVLGTRKLMHVAYEEFEKVMVACFEVFQTWDDEYEKLQVLLRDIVKRKREENLKMVWRINPAHRKLQARLDQMRKFRRQHEQLRAVIVRVLRPQVTAVAQQNQGEAPEPQDM----KVAEVLFDAADANAIEEVNLAYENVKEVDGLDVSKEGTEAWEAAMKRYDERIDRVETRITARLRDQLGTAKNANEMFRIFSRFNALFVRPHIRGAIREYQTQLIQRVKDDIESLHDKFKVQYPQSQACKMSHVRDLPPVSGSIIWAKQIDRQLTAYMKRVEDVLGKGWENHVEGQKLKQDGDSFRMKLNTQEIFDDWARKVQQRNLGVSGRIFTIESAR----VRGRSG---NVLKLKVNFLPEIITLSKEVRNLKWLGFRVPLAIVNKAHQANQLYPFAISLIESVRTYERTCEKVEERN--TISLLVAGLKKEVQALIAEGIALVWESYKLDPYVQRLAETVFNFQEKVDDLLIIEEKIDLEVRSLETCMYDHKTFSEILNRVQKAVDDLNLHSYSNLPIWVNKLDMEIERILGVRLQAGLRAWTQVLLGQAEDKAEVDMDTDA---PQVSHKPGGEPKIKNVVHELRITNQVIYLNPPIEECRYKLYQEMFAWKMIVLSLPRIQSQRYQVGVHYELTEEEKFYRNALTRSRDGPVALEESYSAVMGIVTEVEQYVKVWLQYQCLWDMQAENIYNRLGEDLSKWQALLVQIRRARGTFDNAETKKEFGPVVIDYGKVQSKVNLKYDSWHKEVLSKFGQMLGSNMTEFHSQISKSRQELEQHSVDTASTSDAVTFITYVQSLKRKIKQFEKQVELYRNGQRLLEKQRFQFPPSWLYIDNIEGEWGAFNDIMRRKDSAIQQQVANLQMKIVQEDRAVESRTTDLLTDWEKTKPVTGNLRPEEALQALTIYEGKFGRLKDDREKCAKAKEALELTDTGLLSGSEERVQVALEELQDLKGVWSELSKVWEQIDQMKEQPWVSVQPRKLRQNLDGLLNQLKNFPARLRQYASYEFVQRLLKGYMKINMLVIELKSEALKDRHWKQLMKRLHVNWVVSELTLGQIWDVDLQKNEAIVKDVLLVAQGEMALEEFLKQIREVWNTYELDLVNYQNKCRLIRGWDDLFNKVKEHINSVSAMKLSPYYKVFEEDALSWEDKLNRIMALFDVWIDVQRRWVYLEGIFTGSADIKHLLPVETQRFQSISTEFLALMKKVSKSPLVMDVLNIQGVQRSLERLADLLGKIQKALGEYLERERSSFPRFYFVGDEDLLEIIGNSKNVAKLQKHFKKMFAGVSSIILNEDSSVVLGISSREGEEVMFKTPVSITEHPKINEWLTLVEKEMRVTLAKLLAESVTEVEIFGKATSIDPNTYITWIDKYQAQLVVLSAQIAWSENVENALSNVGGGGNVGPLQSVLSNVEVTLNVLADSVLMEQPPLRRRKLEHLITELVHQRDVTRSLIKSKIDNAKSFEWLSQMRFYFDPKQTDVLQQLSIQMANAKFNYGFEYLGVQDKLVQTPLTDRCYLTMTQALEARLGGSPFGPAGTGKTESVKALGHQLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLSAVSQQVQCIQEALREHSNPNYDKTSAPITCELLNKQVKVSPDMAIFITMNPGYAGRSNLPDNLKKLFRSLAMTKPDRQLIAQVMLYSQGFRTAEVLANKIVPFFKLCDEQLSSQSHYDFGLRALKSVLVSPGNVKRERIQKIKREKEERGEAVDEGEIAENLPEQEILIQSFCETMVPKLVAEDIPLLFSLLSDVFPGVQYHRGEMTDLREELKKVCKEMYLTYGDGEEVGG-MWVEKVLQLYQITQINHGLMMVGPSGSGKSMAWRVLLKALERLEGVEGVAHIIDPKAISKDHLYGTLDPNTREWTDGLFTHVLRKIIDNVRGELQKRQWIVFDGDVDPEWVENLNSVLDDNKLLTLPNGERLSLPPNVRIMFEVQDLKYATLATVSRCGMVWFSEDLLSTDMIFNNFLARLRTIPLDEGEDE--AQRRRKGKEDEGEEAASPMLQIQRDAATIMQPYFTSNGLVTKALEHAFKLEHIMDLTRLRCLGSLFSMLHQGCRNVAQYNANHPDFPMQIEQLERYIQRYLVYAILWSLSGDSRLKMRAELGEYIRRITTVPLPTAPNIP-IIDYEVSISGEWSPWQAKVPQIEVETHKVAAPDVVVPTLDTVRHEALLYTWLAEHKPLVLCGPPGSGKTMTLFSALRALPDMEVVGLNFSSATTPELLLKTFDHYCEYRRTPNGVVLAPVQLGKWLVLFCDEINLPDMDKYGTQRVISFIRQMVEHGGFYRTSDQTWVKLERIQFVGACNPPTDPGRKPLSHRFLRHVPVVYVDYPGPASLTQIYGTFNRAMLRLIPSLRTYAEPLTAAMVEFYTMSQERFTQDTQPHYIYSPREMTRWVRGIFEALRPLETLPVEGLIRIWAHEALRLFQDRLVEDEERRWTDENIDMVALKHFPNIDKEKAMSRPILYSNWLSKDYIPVDQEELRDYVKARLKVFYEEELDVPLVLFNEVLDHVLRIDRIFRQPQGHLLLIGVSGAGKTTLSRFVAWMNGLSVYQIKVHRKYTGEDFDEDLRTVLRRSGCKNEKIAFIMDESNVLDSGFLERMNTLLANGEVPGLFEGDEYATLMTQCKEGAQKEGLMLDSHEELYKWFTSQVIRNLHVVFTMNPSSEGLKDRAATSPALFNRCVLNWFGDWSTEALYQVGKEFTSKMDLEKPNYIVPDYMPVVYDKL-PQPPTHREAIVNSCVFVHQTLHQANARLAKRGGRTMAITPRHYLDFINHYANLFHEKRSELEEQQMHLNVGLRKIKETVDQVEELRRALRIKSQELEVKNAAANDKLKKMVKDQQEAEKKKVMSQEIQEQLHKQQEVIADKQMSVKEDLDKVEPAVIEAQNAVKSIKKQHLVEVRSMANPPAAVKLALESICLLLGESTTDWKQIRSIIMRENFIPTIVNFSAEEISDAIREKMKKNYMSNPSYNYEIVNRASLACGPMVKWAIAQLNYADMLKRVEPLRNELQKLEDDAKDNQQKANEVEQMIRDLEASIARYKEEYAVLISEAQAIKADLAAVEAKVNRSTALLKSLSAERERWEKTSETFKNQMSTIAGDCLLSAAFIAYAGYFDQQMRQNLFTTWSHHLQQANIQFRTDIARTEYLSNADERLRWQASSLPADDLCTENAIMLKRFNRYPLIIDPSGQATEFIMNEYKDRKITRTSFLDDAFRKNLESALRFGNPLLVQDVESYDPVLNPVLNREVRRTGGRVLITLGDQDIDLSPSFVIFLSTRDPTVEFPPDLCSRVTFVNFTVTRSSLQSQCLNEVLKAERPDVDEKRSDLLKLQGEFQLRLRQLEKSLLQALNEVKGRILDDDTIITTLENLKREAAEVTRKVEETDIVMQEVETVSQQYLPLSTACSSIYFTMESLKQVHFLYQYSLQFFLDIYHNVLYENPNLKGATDHTQRLSVITKDLFQVAFNRVARGMLHQDHITFAMLLARIKLKGTMGEPTYDAEFQHFLRGKEIVLSAGSTPKVQ--GLTV--EQAEAVARLSCLPAFKDLIAKVQADEQFGIWLESSSPEQTVPYLWTEET-----PATPIGQAIHRLLLIQAFRPDRLLAMAHMFVSTNLGESFMSIMEQPLDLTHIVGTEVKPNTPVLMCSVPGYDASGHVEDLAAEQNTQITSIAIGSAEGFNQADKAINTAVKSGRWVMLKNVHLAPGWLMQLEKKLHSLQPHACFRLFLTMEINPRVPVNLLRAGRIFVFEPPPGVKANMLRTFSSIPVSRMCKSPNERARLYFLLAWFHAVIQERLRYAPLGWSKKYEFGESDLRSACDTVDTWLDDTAKGRQNISPDKIPWSALKTLMAQSIYGGRVDNEFDQRLLNTFLERLFTTRSFDSEFKLACKVDGHKDIQMPDGIRREEFVQWVELLPDAQTPSWLGLPNNAERVLLTTQGVDMISKMLKMQM-LEDEDDLAYAETEKKTRTDFTSDGRPAWMRTLHTTASNWLHLIPQTLSPLKRTVENIKDPLFRFFEREVKMGAKLLQDVRQDLADVVQVCEGKKKQTNYLRTLINELVKGILPRSWSHYTVPAGMTVIQWVSDFSERIKQLQNISQAAAAGGAKELKNIHVCLGALFVPEAYITATRQYVAQANSWSLEELCLEVNVTASQSTTLDACSFGVTGLKLQGATCSNNK-LSLSNAISTVLPLTQLRW-----GKQTSAEKKASVVTLPVYLNFTRADLIFTVDFEIATKEDPRSFYERGVAV 4640
BLAST of Cytoplasmic dynein 1 heavy chain 1 vs. UniProt/SwissProt
Match: sp|P37276|DYHC_DROME (Dynein heavy chain, cytoplasmic OS=Drosophila melanogaster OX=7227 GN=Dhc64C PE=2 SV=2) HSP 1 Score: 6095.77 bits (15813), Expect = 0.000e+0 Identity = 2933/4636 (63.27%), Postives = 3659/4636 (78.93%), Query Frame = 3 Query: 240 LSEPQNEECLTKFINDNQVTTLTIQQT--------KRXXXXXXXXXXXXKISNEVNFESNKSQTSIFIKNNQVIEADKTISSQLQVLSYCDGPPFETMHSLVCYGLLPYFXXXXXXXXXXXXXXXXXMVPSVEKKIAELEIGLLHLQQNIEIPEITLTPHPYVAHIIQEKLLQNKEARVSDFEDKFEDTQFLNQLQAGVNRWIKEIQKVTKLNRDPSTGTALQEISFWLNLEHSLDKIQEKRESLEVALTLAILKQAKRFHATTSFDTDTALSSAKIQVKDYNQLMKDFPINDLLSASQLDKISEALQQIFSHLKKVRATKYPVNRIIKLMEALSRDLTTQLMKVISNMHLMSMPYDEFEKIFTACQQVFSTWEDEYDKMQNLLRDIAKKKREEFTKFAWKMNATHKKLQTRLENIKKFRYQHEQLRQVIVRVLKPVTKVVPSVEAGVPKDQITDKGDKSSTFLP---ESADTSSIDEVNAAYEIVKVIDCLDFAKEENDEWDAAIKRYEERIDRVESRIASHLRDLLGQSKNANEMFRYFSRFNALFVRPHIRGAIGEYQTQLIQRVKDDIEALHNKFKVQYASSTACKMSKVRDLPPVSGSIIWVRQILRQLNAYMKRVEDVLGKDWAQHIEGQKLKADGESFKLKLNTSELFEEWSKKVAEKSLSVAGSIFNVESTRTVVTVRDREPQKITVLKLKVNFLPDVITLAKEVRNMRALGFRTPLSIVNKAHSANQLYPFAISLIESVRTYESTCSKIEEHKMQNISLLTAGLRKDVQLCIHEGVQITWESYRLDQYVQKLAELVFSFQEKVDDLVIVIKEIDFNVKALETCSYNKQTFEEILIRIQEAVDNMSLHQFSNLAQWVSNLDSLVEQRLIVRLEAGLLEWIKVLKGXXXXXXXXXXXXXXXVNSMAKHRLGGKPQIKKLIHELRITNQQMHLYPSIEVATQDILYQMSSWQNIILNLSRIVHSRYQVGLETESDNQKTYKKLLSSLPNSGESLENAYAAVHNILRDANEYVKTWTNYQSLWDLQGDQLFSLIADDNTVWMNVLEEIKSMRKHFDVAETQKEFGPLVIAFGKVQSKVSMKYDNWHKEVLTKFGQNMGKMMTTLYNEVQRARNELEQQSIDSGGTNESVNFITYTQNIKRKMNTWEKQAEACRAGQNILCRDRFQFPNDWLDSENIQGEWSAFKEIMRRKQETISSQVASLQMKITEEDKIVESKTTEVLGNWEKDKPIAGDLTPEEAVNIIQILEGKFNRLKEERENVQKAKEALELTEIGVKPISEEKVTNALSELHDLKNVWNELKSIWEKIRDMKETPWLSVQPRKLRQDIENLTAQLKELPNSFKQYASFEHVRTLLKMYMKVNASIVELKSEAIKERHWRMLMRKLNVSWSLNELQLGKVWDIDLVKNEEIIREVLAIAQGEKALEEYLRQITEVWKNYVLELTNYQSKSKIIKGWDDLFNKVKEHINNVTSMKASPYFKQFEEEATAWEDRLNKINALFDVWIDVQRRWIYLDGIFAGSADIKVLLPVESQRFQSVSTEFLGLMKKVQKSPLVTDVLNIANVQRQLERLADLLGKIQKSLGEYLERQRSSFPRFYFVGDEDLLEIIGNSXXXXXXXXXXXXMFAGVHSIILSEDEKVILGMMSKEGEELRFISPVSIIEHPRINDWLTAMEKEMRVSLAKYLNVAVKEISGWRTESNIDKDKFMVWLDKYQAQIVVLAAQITWSEAVEASLASGVS------LESTMTVVHSTLNMLADTVLYEQPPVRRRKLEHLIIEYVHQRDVLRALHNDGVSSNKNFDWMSQMRFYFDPKQTDPLHQLSIHVANAKFHYGFEYLGVCDRLVQTPLTDRCYLTMTQALEARLGGSPFGPAGTGKTESVKSLGNQLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLSAVSQQIQGIQEALRELMVSKKDSINVELLGKQVHVNPDMAIFITMNPGYAGRSNLPDNLKKLFRSLAMTQPDRQLIAQVMLYSQGFRTAEVLAGKVVPFFKLCDEQLSPQSHYDFGLRALKSVLVSAGNVKRDRIKQEKEKIVARGEE-INETAIAEQLPEQEILIQSVMETMVPKLIADDIPLLYSLLTDVFPGVEYRQAEMKRLREELRKVSENKFLVYSDEPNTAGYLWVEKVLQLYQITTIHHGLMMVGPSGSGKTMACRVLLQALENIDGIEGVAHIIDPKSISKDSLYGYMDPNTREWTDGLFTHILRRIIDSVRGESNKRQWIVFDGDVDPEWVENLNSVLDDNKLLTLPNGERLAIPPNVRIMFEVQDLKYATLATVSRCGMVWFSEEVLTTGMILTHFLNELKKVQVMEGEEDFSVNQGDTGADADSKISSSPIIQLQTQVSSILAPFFTEDGLIAKCLDYSTTLEHIMDFTRLRALTSLFSMIKQSIRNMIEYNQSHSDFPLNNEQIENYVAKSLISSVVWSMSGDSKLKVREQLSQYIKNISTVDLPTVGGIKNIIDFEVNIQGTWVAWSNKVPQIEVETHKITATDVVVPTMDTVRHEALLYTWLAEHRPVLLCGPPGSGKTMTLFSALRCLPDMEVVGLNFSSATTPELMLKTFDQYCEYRKTPNGIVLAPQQLNKWLIFFCDEINLPDMDKYGTQRVISFLRQMVEHHGFYRITDMQWVSFERIQFVGACNPPTDPGRKPLSHRFLRHVPVVYVDYPGETSLKQIYSTFNRAMLRMLPSLRGYADTLTNAMVEFFLKTQERFTHDMQPHYIYSPREMTRWVRGIHEALKPLESLSVEGLVRIWAHEALRLFQDRLVEEDERHWTDDNINEVALKHFPNINKEEALKRPILYSNWLSKDYSAVTQEELRDYVKARLKVFYEEELDVPLVLFNQVLDHVLRIDRVFRQPQGHLLLIGVSGAGKTTLSRFVSWINGLSVFQVKVHNKYTAEDFDEDLRNVLRRSGCKGEKITFIMDESNVMDSSFLERMNTLLANGEVPGLFEGDELTTLMTQCKEGAIREGLMIDSQEELYKWFTQQICRNLHVVFTMNPSADGLKDKASTSPALFNRCVLNWFGDWSLEAYFQVGKEFTNRLDLERTDYKVPDTLPCIAEGLLPQNPIYRDVVVNALVFVHQTMHQANVRVQKRGGRTAAITPRHYLDLIAHYMKLSAEKRADLEEQQLHLNNGLKKIEQTVDQVEVMQRSLTKKRQELENMNEAANAKLKQMVQDQQEAEQKKTTGQALKEELAKQEQFVNEKQKTVKQELDQVEPTVNEAKQAVQNIRKKDIQEIKAMKNPPNAVKMAVESICLLLGEKTTDWQSILKVIIKDTFVTSIL-NFNTDDVSDNTRETMKKKYLSNPDYNFEKVNKASNACGPMVKWVLAQISYADILKRVEPLRNELTELSDAAEQNRKKSQETEDLIAQLEKSIAKYTEEYATLISQAQTIKSDLASVESKVGRSVALLGSLSSERTRWDSGSETFKAQMATINGDCLLSSAFMAYGGYFDQHMRTSLFNTWCHHLSEADILFRSDLARVEYLSNPDDRLRWQANSLPADDLCVENAIILRRYNRYPLIIDPSGQATTFLLNEYKEKKITKTSFLDDSFRKTLESALRFGTPLLVQDVESYDPILNPVLNREVRRTGGRTLITLGDQDIDLSPTFTIFLSTRDPSVEFAPDICSRVTFVNFTVTRSSLQNQCLNAVLKIERPDIDQKRSDLLKAQGEFQLKLRHLEKDLLQSLNEAQGNLLENDKIIARLETLKREAADVAKKVEETDVVMQEVESVSTEYVPLAQSCSNIYFTLEAMNQIHFLYQYSLQLMLDIFSSVLINNPELTNVKAASDRLKIITKNLFQVTYNRLARGMLHEDQITFATILARIFLKGSTPIGFLENEFQHFLRSQEATITSSDSNKQDNLGLTLHQDQIDSVKRLK-KLKVFAKIEEKVKSTKDIKNWTLTVTPESNVPELWVDDNNYNDEKLSKIAKGMYNLLIIQAIRPDRLLASTQKFIASVLGDTFTESVRGTLDLASIVEVEVTACVPILLCAVQGYDPSGRVEDLASEQGKQLTGIAIGSAEGFSQAEKAINSAAKTGKWVMLKNVHLATSWLVSLEKKIHSLQAHPNFRLFLTMEITPKLPVNLLRAGRVLVFEPPPGIKANLLRTLSSINNQRMSKEPVERSRLYFLLAWLNAIVQERLRYVPLGYSKKYEFGESDFKCALDTIDTWVDGAAMGRTNLPPEKIPWVALQTLLGSCIYGGKIDNAFDQRLLNSFLGYLFTEKCFDHNFALVSDADDGS----NIAFPESTKHTDILQWVHKLPDLQTPSWLGLPNSAEKVLLTNLGQSLIGNILKMQQSLEDDEELVVGQSKTKRTIEVG---DGRPAWMRQLYQSTQTWLQILPKSVTPLQRTIENIKDPMYRCFEREVNSGCNLLASVRKDLEDVAEVCKGAKKPTNHHRSMMADLAKGIIPKMWIRYAIPPGLTVIQWIQDFADRIKQLLHISDTAAKSGVIALRSIQVWLGGLFMAEAYITATRQSVAQNNKWALEELFLDVELGEG--KVDSNTCV--ITGLRLMGSEIVDPRTLKLSTLIYKDIDICRLKWIRVEKSQQLEGSSAKDKVCLPIYLNAARSTVLFT--LYFSTTDSSYDFYKRGVAI 14048 L +P N++ + KF++D QV L +Q+ + E E + + ++ISN+V+F +++ + IK V+EADK+I SQL+++++ DG P+ET+H+ + L PYFKSY+K+ G+ M PSVEKK+AELE+GLLHLQQNI+IPEITLT H V ++I++ +N++A+V+DF DK ED+ FLN LQ GVNRWI EI+KVTKLNRDP +GTALQEISFWLNLE +L +IQEKRES EVALTL ILK KRFHAT SFDTDT L A V DYN LMKDFPINDLLSA++L+KI A+QQIF+HL+KVR TKYP+ R +KL+EA+SRDL+ QL+KV+ LM +P+DEFE++ C ++FS W+DEYDK+Q LLRDI KKKR+E K W+++ HKKLQTR+E+++KFR QHEQLR VI+RVL+P K + D G+ T P ++AD ++I+EVN AYE VK +DCLD KE ++ W+AA+KRYEE+IDRVE+RI +HLRD LG +KNANEMFR FSRFNALFVRPHIRGAI EYQTQLIQRVKDDIEALH KFKVQY S +C++S VRDLPPV+GSIIW RQI QL Y+KRVEDVLGK W HIEGQKLKADG+SF+ KL+ S++F EW++KV E++ G IF +ESTR+ + + VL+L+VNFLP++ITLAKEVRN++ LGFR PL+IVNKAH ANQ+YP+AISLIESVRTYE T KIE+ +I L AGLRKDV + EG+ + WESY+LD YV +L+E V FQEKVDDL++V +++D +V++LETC Y+ TF EIL +IQ AVD++SL Q+SNL+ WV+ LD VE++L +RL+AG+ W + L G +E + + H+LGG PQI+ +HE+RITNQQM+LYPSIE A I+ Q +WQ I+ + R+ +RYQVGLE +TY+ LL+ LP G+ LENAY A+ + + YV W YQSLWDLQ D L+ + +D +W+ L +IK R FD ++T++ +GP++I + KVQ+KV++KYD+WHKE L KFG +G MT+ +++V ++R +LE QSI++ T+++V+FITY Q++K+ M W+KQ E R Q IL R RFQFPN WL +NI+GEWSAF EI++RK I +QVASLQ KI EDK VE++T + L +WEK KP G + P++A+ +QI E K++RLKEER+NV KAKEALEL E V S E++ AL EL DL+ VW+EL +W +I + +E PWLSVQPRKLRQ +E + AQLKELP + Y S+E+V+ L++ Y+KVN IVELKS+A+KERHW+ L ++L V+W L++L LG+VWD++L KNE I+++++ +AQGE ALEE+L+Q+ E W+NY L+L NYQ+K +II+GWDDLFNKVKEHIN+V +MK SPY+K FEEEA WE++LN+INALFDVWIDVQRRW+YL+GIF+GSADIK LLPVE+ RFQS+S+EFLGLMKKV KSP V DVLNI VQR LERLADLLGKIQK+LGEYLER+R+SFPRFYFVGDEDLLEIIGNSK++ +LQKHFKKMFAGV +I+L+E+ VILG+ S+EGEE+ F++PVS +EHP+IN+WL+ +EK+MR +LA L AV++I +R + ID +M W DKYQAQIVVLAAQI WSE VE++L ++ + V STLN+LAD+VL EQPP+RRRKLEHLI E+VH+R V R L N+GV+S K+F W+ +MRFYFDP+QT+ L QL+IH+ANA+F YGFEYLGV DRLVQTPLTDRCYLTMTQALE+RLGGSPFGPAGTGKTESVK+LGNQLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLSA SQQIQ IQEAL+ M S K+SI VEL+GKQV V+PDMAIFITMNPGYAGRSNLPDNLKKLFRSLAMT PDRQLIA+VML+SQGFR+AE LA K+VPFFKLCDEQLS QSHYDFGLRALKSVL+SAGNVKRDRI + KE++ RG+E I+E ++AE LPEQEILIQSV ETMVPKL+A+DIPLL+SLL+DVFP V Y +AEMK L+EE+RKV + +LV E + G W+EKVLQLYQI+ ++HGLMMVGPSGSGK+ A + LL+ALE +G+EGVAH+IDPK+ISK++LYG +DPNTREWTDGLFTHILR+IID+VRGE NKRQWI+FDGDVDPEWVENLNSVLDDNKLLTLPNGERL++PPNVR+MFEVQDLK+ATLATVSRCGMVWFSE+VL+T MI ++L+ L+ + + +G+EDF G D + SP +Q+Q ++ +L PFF+ DG++ + L+Y+ EHIMDFTRLRAL+SLFSM+ Q+ RN++ +N H DFP + +Q+E+Y+ K+L+ SV+WS +GD+KLKVR L ++++++TV LP G IID+EVN+ G WV WSNKVP IEVETHK+ + D+VVPT+DTVRHE+LLYTWLAEH+P++LCGPPGSGKTMTLFSALR LPDMEVVGLNFSSATTPEL+LKTFD YCEYRKTPNG+VL+P Q+ KWL+ FCDEINLPDMD YGTQRVISFLRQ+VEH GFYR +D WVS ERIQFVGACNPPTDPGRKPLSHRFLRHVP++YVDYPGETSLKQIY TF+RAMLR++P+LRGYA+ LTNAMVEF+L +Q+RFT DMQPHY+YSPREMTRWVRGI EA++PL+SL VEGLVR+WAHEALRLFQDRLV++ ER WT++NI+ V KHFP IN+EEAL+RPILYSNWLSKDY V +EELR+YV ARLKVFYEEELDVPLVLF++VLDHVLRIDR+FRQPQGHLLLIGVSGAGKTTLSRFV+W+NGLS+FQ+KVHNKYT+EDFDEDLR VLRRSGCK EKI FI+DESNV+DS FLERMNTLLANGEVPGLFEGDE TTLMTQCKEGA REGLM+DS +ELYKWFTQQ+ RNLHVVFTMNPS DGLKD+A+TSPALFNRCVLNWFGDWS A FQVGKEFT R+DLE+ ++ PD P + L+P NP +RD V+N+ V+VHQT+HQAN R+ KRGGRT A+TPRHYLD I H++KL EKR+DLEEQQLHLN GL KI +TV+QVE MQ+SL K+QEL+ NEAANAKLKQM QDQQEAE+KK Q ++ LA Q + EK+K V +L QVEP V +A+ AV++IRK+ + E++ M NPP+ VK+A+ESICLLLGE TDW+SI VI+++ F+ SI+ NF T++++D+ RE MK KYLSNPDYNFEKVN+AS ACGPMVKW +AQI YAD+LKRVEPLR EL L + A+ N ++ET+DL+ QLE+SIA Y EEYA LISQAQ IK+DL +V++KV RS+ALL SL+ ER RW+S SETFK+QM+TI GD LLS+AF+AYGGYFDQH R +LF TW HL A I +R+D+AR EYLSNPD+RLRWQAN+LP DDLC ENAI+L+R+NRYPLIIDPSGQATTFLLNEY KKITKTSFLDDSFRK LESALRFG PLLVQDVE+YDPILNPVLNRE+RRTGGR LITLGDQDIDLSP+F IFLSTRDP+VEF PDICSRVTFVNFTVTRSSLQ+QCLN VLK ERPDID+KRSDLLK QGEF+L+LR LEK LLQ+LN+A+G +L++D +I LETLK+EA D+ +KV+ETD V+ E+E+VS +Y+PL+ +CSNIYFT++++NQ+HFLYQYSL++ LDIFS+VL NNP+L S+RL I+T++LFQV Y R+ARGM+H D++TFA ++ +I LKG++ L+ EF FLRS+E + +N GL+ +QI+SV RL +L +F K+ EKV+S ++ W +PE VP+LW + + LS IA ++ LL+IQA RPDR++A+ + +VLG+ F + LD S+V+ ++ P LLC+V G+D SGRV+DLA+EQ KQ++ IAIGSAEGF+QAE+AIN A KTG+WV+LKNVHLA WLV LEKK+HSLQ H FRLFLTMEI PK+PVNLLRAGR+ VFEPPPGI+ANLLRT S++ RM K P ER+RLYFLLAW +AIVQERLRYVPLG++KKYEF ESD + A DT+DTW+D AMGRTNLPPEK+PW AL TLL IYGGKIDN FDQRLL SFL LFT + F+ +FALV++ D S +I P+ T+ L+W+ L D QTPSWLGLPN+AEKVLLT G L+ +LKMQQ LEDD+EL VG DGRP+WM+ L+ S WL++LPK++ L+RT+ENIKDP+YR FEREV SG LL +V DL+DV +C+G KK TNHHRSM+++L +GIIPK W RY +P G TVIQWI DF++R++QL +S +++G L+ VWLGGL EAYITATRQ VAQ N W+LEEL LDV + + K D C +TGL+L G++ + L L++ I D+ + LKWI++ ++ K+ LP+YLN+ R+ +LFT L + S+ FY+RGVA+ Sbjct: 52 LDDPVNQDTIRKFLSDPQVQALYVQRNCIKEDDSEQPAEGEDEKEQVTYQISNDVHFTNSRMASLACIKRGLVVEADKSIHSQLRLINFSDGSPYETLHAFISKSLAPYFKSYVKESGRADRDGDK-MAPSVEKKLAELEMGLLHLQQNIDIPEITLTAHQTVNNVIRKCAEENRKAKVADFGDKVEDSSFLNLLQNGVNRWIAEIKKVTKLNRDPGSGTALQEISFWLNLERALYRIQEKRESPEVALTLDILKHGKRFHATVSFDTDTGLKQALATVADYNPLMKDFPINDLLSATELEKIRPAVQQIFAHLRKVRNTKYPIQRCLKLIEAISRDLSQQLLKVLGTRRLMHIPFDEFERVMNQCFEIFSCWDDEYDKLQGLLRDIVKKKRDEHLKMVWRVSPAHKKLQTRMEHMRKFRRQHEQLRTVILRVLRPT------------KPAVGDDGNVVETKQPYSLDAADANAIEEVNLAYENVKEVDCLDITKEGSEAWEAAVKRYEEKIDRVETRITAHLRDQLGTAKNANEMFRIFSRFNALFVRPHIRGAIREYQTQLIQRVKDDIEALHEKFKVQYPQSKSCRLSSVRDLPPVAGSIIWARQIDNQLTMYLKRVEDVLGKGWETHIEGQKLKADGDSFRAKLSISDVFHEWARKVQERNFGSTGRIFTIESTRSRIG-------RGNVLRLRVNFLPEIITLAKEVRNIKNLGFRVPLTIVNKAHQANQIYPYAISLIESVRTYERTLEKIEDRA--SIVPLVAGLRKDVLNLVSEGIGLIWESYKLDPYVIRLSECVTQFQEKVDDLLVVEEQLDVDVRSLETCPYSAATFVEILSKIQHAVDDLSLRQYSNLSVWVTRLDEEVEKKLALRLQAGIQAWTEALTGNKKEVDTSMDTD---APAQPTHKLGGDPQIQNAVHEIRITNQQMYLYPSIEEARFQIMQQFFAWQAIVTSQVRLQSTRYQVGLEKHVS--QTYRNLLTKLP-EGKILENAYGAIEQKVSEVRNYVDEWLRYQSLWDLQADMLYGRLGEDVNLWIKCLNDIKQSRTTFDTSDTRRAYGPIIIDYAKVQAKVTLKYDSWHKEALGKFGTLLGTEMTSFHSKVSKSRTDLEMQSIEAASTSDAVSFITYVQSLKKDMIAWDKQVEVFREAQRILERQRFQFPNTWLHVDNIEGEWSAFNEIIKRKDTAIQTQVASLQAKIVAEDKAVETRTVDFLNDWEKTKPTGGKIRPDDALQQLQIFESKYSRLKEERDNVVKAKEALELQESAVPNNSAERMNVALEELQDLRGVWSELSKVWTQIDETREKPWLSVQPRKLRQQLEAMMAQLKELPARLRMYESYEYVKKLIQSYIKVNMLIVELKSDALKERHWKQLTKQLRVNWVLSDLSLGQVWDVNLQKNEGIVKDIILVAQGEMALEEFLKQVRESWQNYELDLINYQNKCRIIRGWDDLFNKVKEHINSVAAMKLSPYYKVFEEEALTWEEKLNRINALFDVWIDVQRRWVYLEGIFSGSADIKTLLPVETSRFQSISSEFLGLMKKVTKSPKVMDVLNIPAVQRSLERLADLLGKIQKALGEYLERERTSFPRFYFVGDEDLLEIIGNSKNIARLQKHFKKMFAGVAAILLNEENNVILGISSREGEEVHFMNPVSTVEHPKINEWLSLVEKQMRFTLASLLAQAVQDIKQFR-DGKIDPQAYMEWCDKYQAQIVVLAAQILWSEDVESALQQASENNQSKPMQRVLGNVESTLNVLADSVLQEQPPLRRRKLEHLINEFVHKRTVTRRLLNNGVTSPKSFQWLCEMRFYFDPRQTEVLQQLTIHMANARFFYGFEYLGVQDRLVQTPLTDRCYLTMTQALESRLGGSPFGPAGTGKTESVKALGNQLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLSACSQQIQTIQEALKYEMDSNKESITVELVGKQVRVSPDMAIFITMNPGYAGRSNLPDNLKKLFRSLAMTTPDRQLIAEVMLFSQGFRSAEKLACKIVPFFKLCDEQLSNQSHYDFGLRALKSVLISAGNVKRDRIMKIKEQMKQRGDENIDEASVAENLPEQEILIQSVCETMVPKLVAEDIPLLFSLLSDVFPNVGYTRAEMKGLKEEIRKVCQEDYLV-CGEGDEQGAAWMEKVLQLYQISNLNHGLMMVGPSGSGKSTAWKTLLKALERFEGVEGVAHVIDPKAISKEALYGVLDPNTREWTDGLFTHILRKIIDNVRGEINKRQWIIFDGDVDPEWVENLNSVLDDNKLLTLPNGERLSLPPNVRVMFEVQDLKFATLATVSRCGMVWFSEDVLSTEMIFENYLSRLRSIPLEDGDEDFV---GVIKPAKDKEEEVSPSLQVQRDIALLLLPFFSADGIVVRTLEYAMDQEHIMDFTRLRALSSLFSMLNQAARNVLTFNAQHPDFPCSADQLEHYIPKALVYSVLWSFAGDAKLKVRIDLGDFVRSVTTVPLPGAAGAP-IIDYEVNMSGDWVPWSNKVPVIEVETHKVASPDIVVPTLDTVRHESLLYTWLAEHKPLVLCGPPGSGKTMTLFSALRALPDMEVVGLNFSSATTPELLLKTFDHYCEYRKTPNGVVLSPVQIGKWLVLFCDEINLPDMDSYGTQRVISFLRQLVEHKGFYRASDQAWVSLERIQFVGACNPPTDPGRKPLSHRFLRHVPIIYVDYPGETSLKQIYGTFSRAMLRLMPALRGYAEPLTNAMVEFYLASQDRFTQDMQPHYVYSPREMTRWVRGICEAIRPLDSLPVEGLVRLWAHEALRLFQDRLVDDSERRWTNENIDLVGQKHFPGINQEEALQRPILYSNWLSKDYMPVNREELREYVHARLKVFYEEELDVPLVLFDEVLDHVLRIDRIFRQPQGHLLLIGVSGAGKTTLSRFVAWMNGLSIFQIKVHNKYTSEDFDEDLRCVLRRSGCKDEKIAFILDESNVLDSGFLERMNTLLANGEVPGLFEGDEYTTLMTQCKEGAQREGLMLDSSDELYKWFTQQVMRNLHVVFTMNPSTDGLKDRAATSPALFNRCVLNWFGDWSDSALFQVGKEFTTRVDLEKPNWHAPDFFPSVCP-LVPANPTHRDAVINSCVYVHQTLHQANARLAKRGGRTMAVTPRHYLDFIHHFVKLYNEKRSDLEEQQLHLNVGLNKIAETVEQVEEMQKSLAVKKQELQAKNEAANAKLKQMFQDQQEAEKKKIQSQEIQIRLADQTVKIEEKRKYVMADLAQVEPAVIDAQAAVKSIRKQQLVEVRTMANPPSVVKLALESICLLLGENATDWKSIRAVIMRENFINSIVSNFGTENITDDVREKMKSKYLSNPDYNFEKVNRASMACGPMVKWAIAQIEYADMLKRVEPLREELRSLEEQADVNLASAKETKDLVEQLERSIAAYKEEYAQLISQAQAIKTDLENVQAKVDRSIALLKSLNIERERWESTSETFKSQMSTIIGDVLLSAAFIAYGGYFDQHYRLNLFTTWSQHLQAASIQYRADIARTEYLSNPDERLRWQANALPTDDLCTENAIMLKRFNRYPLIIDPSGQATTFLLNEYAGKKITKTSFLDDSFRKNLESALRFGNPLLVQDVENYDPILNPVLNRELRRTGGRVLITLGDQDIDLSPSFVIFLSTRDPTVEFPPDICSRVTFVNFTVTRSSLQSQCLNQVLKAERPDIDEKRSDLLKLQGEFRLRLRQLEKSLLQALNDAKGKILDDDSVITTLETLKKEAYDINQKVDETDKVIAEIETVSQQYLPLSVACSNIYFTMDSLNQVHFLYQYSLKMFLDIFSTVLYNNPKLEGRTDHSERLGIVTRDLFQVCYERVARGMIHIDRLTFALLMCKIHLKGTSESN-LDAEFNFFLRSREGLL----ANPTPVEGLS--AEQIESVNRLALRLPIFRKLLEKVRSIPELGAWLQQSSPEQVVPQLWDE-----SKALSPIASSVHQLLLIQAFRPDRVIAAAHNVVNTVLGEDFMPNAEQELDFTSVVDKQLNCNTPALLCSVPGFDASGRVDDLAAEQNKQISSIAIGSAEGFNQAERAINMACKTGRWVLLKNVHLAPQWLVQLEKKMHSLQPHSGFRLFLTMEINPKVPVNLLRAGRIFVFEPPPGIRANLLRTFSTVPAARMMKTPSERARLYFLLAWFHAIVQERLRYVPLGWAKKYEFNESDLRVACDTLDTWIDTTAMGRTNLPPEKVPWDALVTLLSQSIYGGKIDNDFDQRLLTSFLKKLFTARSFEADFALVANVDGASGGLRHITMPDGTRRDHFLKWIENLTDRQTPSWLGLPNNAEKVLLTTRGTDLVSKLLKMQQ-LEDDDELAYSVEDQSEQSAVGRGEDGRPSWMKTLHNSATAWLELLPKNLQVLKRTVENIKDPLYRYFEREVTSGSRLLQTVILDLQDVVLICQGEKKQTNHHRSMLSELVRGIIPKGWKRYTVPAGCTVIQWITDFSNRVQQLQKVSQLVSQAGAKELQGFPVWLGGLLNPEAYITATRQCVAQANSWSLEELALDVTITDAGLKNDQKDCCFGVTGLKLQGAQCKNNELL-LASTIMMDLPVTILKWIKISSEPRI------SKLTLPVYLNSTRTELLFTVDLAVAAGQESHSFYERGVAV 4632
BLAST of Cytoplasmic dynein 1 heavy chain 1 vs. UniProt/SwissProt
Match: sp|Q19020|DYHC_CAEEL (Dynein heavy chain, cytoplasmic OS=Caenorhabditis elegans OX=6239 GN=dhc-1 PE=1 SV=1) HSP 1 Score: 4838.09 bits (12548), Expect = 0.000e+0 Identity = 2390/4571 (52.29%), Postives = 3230/4571 (70.66%), Query Frame = 3 Query: 384 FESNKSQTSIFIKNNQVIEADKTISSQLQVLSYCDGPPFETMHSLVCYGLLPYFXXXXXXXXXXXXXXXXXMVPSVEKKIAELEIGLLHLQQNIEIPEITLTPHPYVAHIIQEKLLQNKEARVSDFEDKFEDTQFLNQLQAGVNRWIKEIQKVTKLNRDPSTGTALQEISFWLNLEHSLDKIQEKRESLEVALTLAILKQAKRFHATTSFDTDTALSSAKIQVKDYNQLMKDFPINDLLSASQLDKISEALQQIFSHLKKVRATKYPVNRIIKLMEALSRDLTTQLMKVISNMHLMSMPYDEFEKIFTACQQVFSTWEDEYDKMQNLLRDIAKKKREEFTKFAWKMNATHKKLQTRLENIKKFRYQHEQLRQVIVRVLKPVTKVVPSVEAGVPKDQI---TDKGDKSSTFLPESADTSSIDEVNAAYEIVKVIDCLDFAKEENDEWDAAIKRYEERIDRVESRIASHLRDLLGQSKNANEMFRYFSRFNALFVRPHIRGAIGEYQTQLIQRVKDDIEALHNKFKVQYASSTACKMSKVRDLPPVSGSIIWVRQILRQLNAYMKRVEDVLGKDWAQHIEGQKLKADGESFKLKLNTSELFEEWSKKVAEKSLSVAGSIFNVESTRTVVTVRDREPQKITVLKLKVNFLPDVITLAKEVRNMRALGFRTPLSIVNKAHSANQLYPFAISLIESVRTYESTCSKIEEHKMQNISLLTAGLRKDVQLCIHEGVQITWESYRLDQYVQKLAELVFSFQEKVDDLVIVIKEIDFNVKALETCSYNKQTFEEILIRIQEAVDNMSLHQFSNLAQWVSNLDSLVEQRLIVRLEAGLLEWIKVLKGXXXXXXXXXXXXXXXVNSMAKHRLGGKPQIKKLIHELRITNQQMHLYPSIEVATQDILYQMSSWQNIILNLSRIVHSRYQVGLETESDNQKTYKKLLSSLPNSGESLENAYAAVHNILRDANEYVKTWTNYQSLWDLQGDQLFSLIADDNTVWMNVLEEIKSMRKHFDVAETQKEFGPLVIAFGKVQSKVSMKYDNWHKEVLTKFGQNMGKMMTTLYNEVQRARNELEQQSIDSGGTNESVNFITYTQNIKRKMNTWEKQAEACRAGQNILCRDRFQFPNDWLDSENIQGEWSAFKEIMRRKQETISSQVASLQMKITEEDKIVESKTTEVLGNWEKDKPIAGDLTPEEAVNIIQILEGKFNRLKEERENVQKAKEALELTEIGVKPISEEKVTNALSELHDLKNVWNELKSIWEKIRDMKETPWLSVQPRKLRQDIENLTAQLKELPNSFKQYASFEHVRTLLKMYMKVNASIVELKSEAIKERHWRMLMRKLNVSWSLNELQLGKVWDIDLVKNEEIIREVLAIAQGEKALEEYLRQITEVWKNYVLELTNYQSKSKIIKGWDDLFNKVKEHINNVTSMKASPYFKQFEEEATAWEDRLNKINALFDVWIDVQRRWIYLDGIFAGSADIKVLLPVESQRFQSVSTEFLGLMKKVQKSPLVTDVLNIANVQRQLERLADLLGKIQKSLGEYLERQRSSFPRFYFVGDEDLLEIIGNSXXXXXXXXXXXXMFAGVHSIILSEDEKVILGMMSKEGEELRFISPVSIIEHPRINDWLTAMEKEMRVSLAKYLNVAVKEISGWRTESNIDKDKFMVWLDKYQAQIVVLAAQITWSEAVEASLASGVSLESTMTVVHSTLNMLADTVLYEQPPVRRRKLEHLIIEYVHQRDVLRALHNDGVSSNKNFDWMSQMRFYFDPKQTDPLHQLSIHVANAKFHYGFEYLGVCDRLVQTPLTDRCYLTMTQALEARLGGSPFGPAGTGKTESVKSLGNQLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLSAVSQQIQGIQEALRELMVSKKDSINVELLGKQVHVNPDMAIFITMNPGYAGRSNLPDNLKKLFRSLAMTQPDRQLIAQVMLYSQGFRTAEVLAGKVVPFFKLCDEQLSPQSHYDFGLRALKSVLVSAGNVKRDRIKQEKEKIVARGEEINETAIAEQLPEQEILIQSVMETMVPKLIADDIPLLYSLLTDVFPGVEYRQAEMKRLREELRKVSENKFLVYSDEPNTAGYLWVEKVLQLYQITTIHHGLMMVGPSGSGKTMACRVLLQALENIDGIEGVAHIIDPKSISKDSLYGYMDPNTREWTDGLFTHILRRIIDSVRGESNKRQWIVFDGDVDPEWVENLNSVLDDNKLLTLPNGERLAIPPNVRIMFEVQDLKYATLATVSRCGMVWFSEEVLTTGMILTHFLNELKKVQVMEGEEDFSVNQGD----TGADADSKISSSPIIQLQTQVSSILAPFFTEDGLIAKCLDYSTT-LEHIMDFTRLRALTSLFSMIKQSIRNMIEYNQSHSDFPLNNEQIENYVAKSLISSVVWSMSGDSKLKVREQLSQYIKNISTVDLPTVGGIKNIIDFEVNIQGTWVAWSNKVPQIEVETHKITATDVVVPTMDTVRHEALLYTWLAEHRPVLLCGPPGSGKTMTLFSALRCLPDMEVVGLNFSSATTPELMLKTFDQYCEYRKTPNGIVLAPQQLNKWLIFFCDEINLPDMDKYGTQRVISFLRQMVEHHGFYRITDMQWVSFERIQFVGACNPPTDPGRKPLSHRFLRHVPVVYVDYPGETSLKQIYSTFNRAMLRMLPSLRGYADTLTNAMVEFFLKTQERFTHDMQPHYIYSPREMTRWVRGIHEALKPLESLSVEGLVRIWAHEALRLFQDRLVEEDERHWTDDNINEVALKHFPNINK-EEALKRPILYSNWLSKDYSAVTQEELRDYVKARLKVFYEEELDVPLVLFNQVLDHVLRIDRVFRQPQGHLLLIGVSGAGKTTLSRFVSWINGLSVFQVKVHNKYTAEDFDEDLRNVLRRSGCKGEKITFIMDESNVMDSSFLERMNTLLANGEVPGLFEGDELTTLMTQCKEGAIREGLMIDSQEELYKWFTQQICRNLHVVFTMNPSADGLKDKASTSPALFNRCVLNWFGDWSLEAYFQVGKEFTNRLDLERTDYKVPDTLPCIAEGLLPQNPIYRDVVVNALVFVHQTMHQANVRVQKRGGRTAAITPRHYLDLIAHYMKLSAEKRADLEEQQLHLNNGLKKIEQTVDQVEVMQRSLTKKRQELENMNEAANAKLKQMVQDQQEAEQKKTTGQALKEELAKQEQFVNEKQKTVKQELDQVEPTVNEAKQAVQNIRKKDIQEIKAMKNPPNAVKMAVESICLLLGEKT-TDWQSILKVIIKDTFVTSILNFNTDDVSDNTRETMKKKYLSNPDYNFEKVNKASNACGPMVKWVLAQISYADILKRVEPLRNELTELSDAAEQNRKKSQETEDLIAQLEKSIAKYTEEYATLISQAQTIKSDLASVESKVGRSVALLGSLSSERTRWDSGSETFKAQMATINGDCLLSSAFMAYGGYFDQHMRTSLFNTWCHHLSEADILFRSDLARVEYLSNPDDRLRWQANSLPADDLCVENAIILRRYNRYPLIIDPSGQATTFLLNEYKEKKITKTSFLDDSFRKTLESALRFGTPLLVQDVESYDPILNPVLNREVRRTGGRTLITLGDQDIDLSPTFTIFLSTRDPSVEFAPDICSRVTFVNFTVTRSSLQNQCLNAVLKIERPDIDQKRSDLLKAQGEFQLKLRHLEKDLLQSLNEAQGNLLENDKIIARLETLKREAADVAKKVEETDVVMQEVESVSTEYVPLAQSCSNIYFTLEAMNQIHFLYQYSLQLMLDIFSSVLINNPELTNVKAASDRLKIITKNLFQVTYNRLARGMLHEDQITFATILARIFLKGSTPIGFLENEFQHFLRSQEATITSSDSNKQDNLGLT-LHQDQIDSVKRLKKL----KVFAKIEEKVKSTKDIKNWTLTVTPESNVPELWVDDNNYNDEKLSKIAKGMYNLLIIQAIRPDRLLASTQKFIASVLGDTFTESVRGTLDLASIVEVEVTACVPILLCAVQGYDPSGRVEDLASEQGKQLTGIAIGSAEGFSQAEKAINSAAKTGKWVMLKNVHLATSWLVSLEKKIHSLQAHPNFRLFLTMEITPKLPVNLLRAGRVLVFEPPPGIKANLLRTLSSINNQRMSKEPVERSRLYFLLAWLNAIVQERLRYVPLGYSKKYEFGESDFKCALDTIDTWVDGAAMGRTNLPPEKIPWVALQTLLGSCIYGGKIDNAFDQRLLNSFLGYLFTEKCFDHNFALVSDADDGSNIAFPESTKHTDILQWVHKLPDLQTPSWLGLPNSAEKVLLTNLGQSLIGNILKMQQSLEDDEELVVGQSKTKRTIEVGDGRPAWMRQLYQSTQTWLQILPKSVTPLQRTIENIKDPMYRCFEREVNSGCNLLASVRKDLEDVAEVCKGAKKPTNHHRSMMADLAKGIIPKMWIRYAIPPGLTVIQWIQDFADRIKQLLHISDTAAKSGVIALRSIQVWLGGLFMAEAYITATRQSVAQNNKWALEELFLDVELGEGKVDSNTCV-ITGLRLMGSEIVDPRTLKLSTLIYKDIDICRLKWIRVEKSQQLEGSSAKDKVCLPIYLNAARSTVLFTLYFSTTDSSYDFYKRGVAI 14048 F +++ Q +F+K + VIEA+K I++Q+ G +E +H L+ L PY DK+ P+V+K E E LLHLQQNI+IPEI L + ++ I++ +N+ A++ D D ED FLN LQ+G NRW+KEI+KVT+L RDPS+GT+LQE++FWLNLE +L KI +KR+ EV LTL LK KRFHAT FD+D L V+DYN LMK+FP+++L+SA+ + K+ A+ IF HL+K+R+TKYP+ R ++L+EA+SRDL +QL+KV+S+ +LM P EF +I + CQ +FS W+DEYDK LLRDI KKKR++ +K +WK+ A HK+L+TRL I +FR QHEQ R VI RVL+PV ++Q+ + +G+KS P+ ++V+ AYE +K +D LD ++ W+ A KRYE++I VE+ I + L+ L S+N+NEMF FSR+NALF+RP IRGAI EYQT+LI RVK+DI L +F + K+ + LPP S I+W+R RQL YMKRVEDVLGK W H++G++LKADG++FK+KLNT +F+EW + V ++ ++ I V+ R V R + L+LK+N+ D L KEV +++++GFR PL IVN AH ANQ+ P A SLIE+ RT+ S + + +Q + L A +KD+Q + EG + W+SY++DQY KLAE V ++QE+ ++L+ V++ ++ ++ L++C Y+K+T E +L IQ+ VD +SL +SNLAQWV+ LD +E L R+E + W V +E + R P +K ++ +L +T Q +++ PS + IL Q+ W ++ RI R+Q+ + E + + TY +L+ +P LE AY V+ I+ D EY+ W +YQSLW LQ +QLF ++ + WM L EI+ R FD +T+K P+ + +GK Q K+ KYD WHKE+L KFG +G M +N V + RN LE QS+D G T++++ I++ Q++K++ + + + R+ Q +L + R+QFP WL SEN++GEWSAF EI+ + +I +Q+ +LQ K +ED++VE +T E L W K KP+ G P+EA+N+I E K N+L EER ++KA+ AL+L++ P +K+T A EL +K+VW L+ ++ I + KE WLSVQPRK+RQ ++ L QLK+LP + Y S+EHV+ +L Y K+N + ELKSEA+KERHW +M+++ V+W+L++L LG+VWD D++++E I+++L +AQGE ALEE+LR++ E W+NY +EL NYQ+K+++IKGWDDLFNK+KEH N++++MK SPY+KQFEE A +W+++LNKINA+FDVWIDVQRRW+YL+G+F+GSA+I LLP ES RF +++T+ L LMKKV SP + DV+N+ QR LERLAD+L KIQK+LGEYLER+RSSFPRFYFVGDEDLLEI+GNSKD+ ++QKH KKMFAG+ +I ++E+++ I S+EGE++ + VS + RINDWL A+E EM+ +LA+ L ++ S ++ + D ++ WLDK+ AQ++ L A+I W + +E +LA G E+ V TL +LAD+VL EQPP+RR+K+E LI E VH+RD R L + + + +F W+ MRFYFDPKQ DP+ + +AN++F YGFEYLG+ +RLV+TPLTDRCYLTMTQAL +RLGGSPFGPAGTGKTESVK+LG+QLGRFVLVFNCDETFDFQAMGRI VGLCQVGAWGCFDEFNRLEERMLSAVSQQIQ IQEA+R ++V+L+GK+++VN ++ IFITMNPGY+GRSNLPDNLK+LFRSLAMTQPDRQLIAQVML+SQGFRTAE LA K+VP F LC EQLS Q HYDFGLRALK VLVSAGN+KRD++ + +A E + EQ++LIQSV ET+VPKL+ +DI LL+SLL+DVFPG+ Y +M+ LR++L V + L+YSD G +W++KVLQLYQIT ++HGLM+VG SGSGKTMA +VLL+ALE + +EGVAH+ID K++SKDSLYG MDPNTREWTDGLFT ++R+IID+VRGE+++RQWI+FDGDVDPEWVENLNSVLDDNKLLTLPNGERL+IPPNVRI+FEV DLKYATLATVSRCGMVWFSEEV+T+ M+ +L+ +++V + + G DA S I++Q + L F+ DG++ L Y+ + LEHIM T R L+S FSM+ SIR ++ +++ D + +QI+++V +S+++++VW+ SGD K K RE +S +I+ +T+ LP +ID+EV + G W W +KVP +E+E+H++ A D+VVPT+DTVRHE LL WLAEH+P++LCGPPGSGKTMTL +ALR +MEVV +NFSS+TTPEL+L+TFD YCEYR+TPNG+VLAP QL++WL+ FCDEINLP DKYGTQRVISFLRQ+VE +GFYR +D WVS ERIQFVGACNPPTDPGR P++ RFLRHVP+VYVDYPG+TSL+QIY TFNRAML+M P++RG AD LTNAMV+ +L +QE FT D QPHY+YSPRE+TRWVRGI EA+ PLESLS E LVR+WAHEA+RLFQDRLV E+ER WTD ++ A ++F N + +EALKRP+LYS WLS++Y VT+EEL+DYV ARLK FYEEELDV LVLF+Q+LDHVLRIDR++RQ QGHLLLIG +GAGKTTLSRFV+W+NGLSVFQ+KVH+KYTA DFDED+R VLRR+GC+ EK+ FIMDESN++D+ FLER+NTLLANGEVPGLFEGDE TTLMTQ KEGA R+GL++DS +ELYKWFTQQ+ RNLHVVFTMNPS GL+++ASTSPALFNRCVLNWFGDWS A +QVG E T +DL+RTDY+ L E L+P P YRD VVN L VH+T+ + N K+G R A TPRH+LD I +M L EKR+DLEE+++HLN GL KI +T +QV+ +Q+SL K EL+ EAAN KLK+M+ DQQ+AE++K + L++ELA+Q + + EK+ V+ +L QVEP V EA+ AVQ I+K + E+K+M +PP VK+ +E+IC+LLGE TDW++I +V++KD F+T IL F+T+ ++ + M +KY+ NPD+ F+KVN+AS ACGPMVKW AQ+ Y+ +L +VEPLRNEL L A + ++ + + I +LE+SI KY EEYA LI QA+ IK DL SV+ KV RS LL SL SER RW SGS F QM ++ GD LLSSAF+AY GY+DQ +R +F+ W +H+ A + FR DLAR+EYLS DDRL+WQ NSLP DDLC ENAI+L R+NRYPLIIDPSGQA +++ ++ K I KTSFLD+SFRK LESALRFG LLVQDVE+YDPILNPVLNREV+R GGR LIT+GDQDIDLSP+F IF+ TRD +VEF+PDICSRVTFVNFTVT SSL +QCLN VL+ ERPD+D+KR+DLLK QGEF ++LRHLEK LL +LNE++G +L+++ +I LE LK EAA+VA+K ETD VM EV++VS +Y L+ +CS+IY TL+ +N+IHFLY YSL +++IF+ VL PEL++ + RL+IIT +LFQ + R++RGMLH D++ A +L RI ++ + E F L + + +++ GL L + S+ + +K+ VFA ++ ++ + +W PESNVP +W D D KLS + M +L+++ A+RPDRL+AS + +++ D F + + +D+ SIV+ EV+ P+LLC+ GYD SG++EDLA E +QLT IAIGSAEGF+QA+ A+ +A K+G+WV+LKNVHLA SWL LEK++HS++ H FRLFLT EI PKLP ++LRA RV+VFEP G+KANLLR+LSSI QR++K P ERSRLY L+ WL+A+VQERLRY PLG+S YEF ++D + A DT+D VD A GR N+ PE++PW L+TLL CIYGGKIDN FDQ LL+ L LFT K F+ + L+ D ++ P +K ++ WV +L + Q P+WLGLPN+AEKVLLT G+S++ N+LK+ DEEL + + +P WM QL + + WLQ+LPK + ++RT+ENIKDP++R FEREVN G LL +R+DL +++ VC+ KK N R++ A L KG +P W RY +P +TV+ W+ D +R+KQL+ I G L+ WLGG F EAYITATRQ VAQ N W+LE+L L + + G+ DS I+G+ + G++ V L+L L+ + DI W D LP+YL R ++ L F + ++ FY+RGVA+ Sbjct: 104 FMTDRGQAMMFVKQSNVIEAEKKIATQVSAFPLNGGSAWEQLHFLMSRLLNPY-CKSFIGQSGRGERDGDKLAPTVQKCFTEAEAALLHLQQNIDIPEINLVVNQHILDAIEQAGKENRRAKIEDLGDLVEDANFLNALQSGCNRWVKEIRKVTQLERDPSSGTSLQEMTFWLNLERALLKISQKRDGEEVTLTLEALKCGKRFHATVGFDSDNGLKQKLAVVQDYNTLMKEFPLSELVSATDVPKLMHAVVGIFLHLRKLRSTKYPLQRALRLVEAISRDLNSQLLKVLSSYNLMRTPIAEFNEIMSQCQALFSKWDDEYDKFIALLRDINKKKRDDPSKLSWKVTAVHKRLETRLMQILQFRKQHEQFRTVIERVLRPVGN------GSREREQLMIDSSEGEKS----PD-------EQVDIAYEFLKNVDFLDV---DSPAWENAFKRYEDQIGVVETAITTRLKSQLESSRNSNEMFSIFSRYNALFIRPRIRGAIYEYQTRLINRVKEDINELQARF-TKARGEQGVKIMQTVGLPPFSAKIMWIRNYERQLQRYMKRVEDVLGKQWENHVDGRQLKADGDNFKVKLNTQPMFDEWVESVQSQNWTLPNKILTVD--RVQVDGRMQ-------LQLKINYHSDSSVLYKEVSHLKSMGFRVPLKIVNWAHQANQMRPSATSLIEAARTFASVNAALA--SVQGVDSLLASYKKDIQNQLIEGATLGWDSYKVDQYQLKLAETVNTYQERCEELLNVVRIVNADLNVLKSCRYDKETIENLLTSIQKGVDQLSLGNYSNLAQWVNTLDRQIETILARRVEDAIRVWTLVFSQSEEVEEL-------------RERQVVLPTVKNVVVDLCMTAQTLYISPSTRETREKILEQLYEWHSVCTAQMRISGKRFQMVMNEEIEPE-TYHNILNVMPEGQACLEKAYDCVNGIMSDLEEYLSEWLSYQSLWVLQAEQLFEMLGTSLSKWMKTLMEIRKGRLVFDTQDTRKVIFPVSVEYGKAQQKILFKYDYWHKEMLVKFGAVVGDEMQKFFNSVSKWRNVLETQSVDGGSTSDTIGLISFVQSLKKQTKSGQDAVDLYRSSQRLLNQQRYQFPAQWLYSENVEGEWSAFTEILSLRDASIQTQMMNLQTKFAQEDELVEKRTVETLTEWNKSKPVEGAQRPQEALNVITAFEAKLNKLTEERNKMRKARVALDLSDSAHAPSEGDKLTVATEELAAMKDVWKALQPVYTGIDEAKEKTWLSVQPRKIRQSLDELMNQLKQLPVKCRTYKSYEHVKQMLHTYGKMNMLVAELKSEALKERHWHQMMKEMRVNWNLSDLTLGQVWDADILRHEHTIKKILLVAQGEMALEEFLREMREYWQNYEVELVNYQNKTRLIKGWDDLFNKLKEHQNSLSAMKLSPYYKQFEESAQSWDEKLNKINAMFDVWIDVQRRWVYLEGLFSGSAEISTLLPFESSRFATITTDVLALMKKVAASPRILDVVNMQGAQRLLERLADMLAKIQKALGEYLERERSSFPRFYFVGDEDLLEIMGNSKDITRIQKHLKKMFAGITAIDINEEDRSITAFHSREGEKVDLVKIVS-TKDVRINDWLQALEAEMKHTLARQLAASLTHFSKMNIQT-MTTDDYVEWLDKFPAQVITLTAEIWWCDEMEKTLADGKGAENVEQAVVKTLELLADSVLKEQPPIRRKKMEALITELVHKRDTCRKLVSMKIRAANDFGWLQCMRFYFDPKQVDPVRCCVVKMANSQFFYGFEYLGIQERLVRTPLTDRCYLTMTQALHSRLGGSPFGPAGTGKTESVKALGHQLGRFVLVFNCDETFDFQAMGRILVGLCQVGAWGCFDEFNRLEERMLSAVSQQIQTIQEAVR-----AGGDMSVDLVGKRLNVNSNIGIFITMNPGYSGRSNLPDNLKQLFRSLAMTQPDRQLIAQVMLFSQGFRTAETLANKIVPLFILCKEQLSDQCHYDFGLRALKYVLVSAGNIKRDKLDKMG------------SAALEDVAEQQMLIQSVCETLVPKLVNEDIALLFSLLSDVFPGIHYTANQMRELRQQLSTVCDEHLLIYSDVQGEMGSMWLDKVLQLYQITNLNHGLMLVGSSGSGKTMAWKVLLKALERWENVEGVAHVIDAKAMSKDSLYGVMDPNTREWTDGLFTSVIRKIIDNVRGEADRRQWIIFDGDVDPEWVENLNSVLDDNKLLTLPNGERLSIPPNVRIIFEVADLKYATLATVSRCGMVWFSEEVVTSEMLFERYLSIIRRVPLDSDSAISFSSSSAPVNLIGEDAKPTRS----IEIQRTAALALQTHFSPDGIVPGSLKYAVSELEHIMPPTPQRLLSSFFSMMSYSIRKIVSHDEGLIDDSVEIDQIQSFVLRSMLTNLVWAFSGDGKWKSREMMSDFIRQATTISLPP-NQQACLIDYEVQLSGDWQPWLSKVPTMEIESHRVAAADLVVPTIDTVRHEMLLAAWLAEHKPLVLCGPPGSGKTMTLLAALRSQQEMEVVNVNFSSSTTPELLLRTFDHYCEYRRTPNGVVLAPVQLSQWLVIFCDEINLPAPDKYGTQRVISFLRQLVELNGFYRTSDHSWVSLERIQFVGACNPPTDPGRHPMTSRFLRHVPIVYVDYPGQTSLQQIYGTFNRAMLKMTPAVRGLADQLTNAMVDVYLASQEHFTQDDQPHYVYSPRELTRWVRGISEAITPLESLSAEQLVRLWAHEAIRLFQDRLVTEEEREWTDKLVDTTAERYFGNACRLDEALKRPLLYSCWLSRNYVPVTREELQDYVSARLKGFYEEELDVKLVLFDQMLDHVLRIDRIYRQSQGHLLLIGTAGAGKTTLSRFVAWLNGLSVFQLKVHSKYTAADFDEDMRTVLRRAGCRNEKLCFIMDESNMLDTGFLERLNTLLANGEVPGLFEGDEHTTLMTQIKEGAQRQGLILDSHDELYKWFTQQVMRNLHVVFTMNPSGSGLRERASTSPALFNRCVLNWFGDWSENALYQVGSELTRTMDLDRTDYEGSVRLTPSCE-LVPSQPTYRDAVVNTLCLVHKTVQKFNEMETKKGHRVMACTPRHFLDFIKQFMSLFHEKRSDLEEEKIHLNIGLNKISETEEQVKELQKSLKLKSNELQEKKEAANLKLKEMLGDQQKAEEEKKFSEQLQKELAEQLKQMAEKKTFVENDLAQVEPAVAEAQTAVQGIKKSQLVEVKSMSSPPVTVKLTLEAICILLGENVGTDWKAIRQVMMKDDFMTRILQFDTELLTPEILKQM-EKYIQNPDWEFDKVNRASVACGPMVKWARAQLLYSTMLHKVEPLRNELKRLEQEAAKKTQEGKVVDVRITELEESIGKYKEEYAQLIGQAENIKQDLLSVQEKVNRSTELLSSLRSERDRWSSGSAGFSQQMDSLVGDALLSSAFLAYAGYYDQMLRDEIFHKWFNHVVNAGLHFRHDLARIEYLSTVDDRLQWQLNSLPVDDLCTENAIMLHRFNRYPLIIDPSGQAVEYIMKQFAGKNIQKTSFLDESFRKNLESALRFGNSLLVQDVEAYDPILNPVLNREVKRAGGRVLITIGDQDIDLSPSFQIFMITRDSTVEFSPDICSRVTFVNFTVTSSSLASQCLNQVLRSERPDVDKKRNDLLKLQGEFAVRLRHLEKALLAALNESKGKILDDNSVIETLEKLKNEAAEVAQKSAETDKVMAEVDAVSAQYQRLSTACSHIYHTLQQLNEIHFLYHYSLDFLVEIFTHVL-KTPELSSTTDYAKRLRIITTSLFQTVFRRVSRGMLHTDKVLLALLLMRIHIRSNPSAPAYEQHFDLLLGRSDFVAKNDEADSTIPGGLDFLTVENKKSIAKARKVVGFENVFAHLQH---NSAAVTSWLTNDNPESNVPVVWDD----ADGKLSPLCIAMNSLIVVHALRPDRLMASAHRVVSTAFDDHFMQQDK-VVDILSIVDNEVSPSEPVLLCSATGYDASGKIEDLAVETNRQLTSIAIGSAEGFNQADSALGTATKSGRWVLLKNVHLAPSWLAQLEKRLHSMKPHAQFRLFLTAEIHPKLPSSILRASRVVVFEPATGLKANLLRSLSSIPPQRLTKAPTERSRLYLLVCWLHALVQERLRYTPLGWSTAYEFSDADLRVACDTLDAAVDAVAQGRPNVEPERLPWTTLRTLLSQCIYGGKIDNQFDQVLLDCVLENLFTAKSFEQDHVLIPKYDGDDSLFTPNMSKKDQMIGWVEELKNEQLPAWLGLPNNAEKVLLTKRGESMLRNMLKVT-----DEELAFNEDGKEEV------KPQWMAQLGELAKQWLQLLPKEIVKMRRTVENIKDPLFRFFEREVNLGSQLLKDIRRDLNEISAVCRAEKKQNNETRALAASLQKGEVPTGWKRYTVPREVTVMDWMTDLNERLKQLIRI------GGADNLKRETFWLGGTFSPEAYITATRQQVAQANTWSLEQLNLHIHI--GRTDSTDVFRISGIDIRGAKSVGGNKLELCELVKSECDIVEFSW----------KQDVADGTRLPLYLYGDRRQLISPLAFHLSSATV-FYQRGVAL 4562
BLAST of Cytoplasmic dynein 1 heavy chain 1 vs. TrEMBL
Match: A0A4S2M0W6 (Uncharacterized protein OS=Opisthorchis felineus OX=147828 GN=CRM22_003509 PE=4 SV=1) HSP 1 Score: 6650.07 bits (17252), Expect = 0.000e+0 Identity = 3212/4736 (67.82%), Postives = 3822/4736 (80.70%), Query Frame = 3 Query: 87 MADITANLVQPPDQEITAISLPKFIKYLTLYAFPCMLNDDESKSRKDYELFLSEPQNEECLTKFINDNQVTTLTIQQ--TKRXXXXXXXXXXXXKISNEVNFESNKSQTSIFIKNNQVIEADKTISSQLQVLSYCDGPPFETMHSLVCYGLLPYFXXXXXXXXXXXXXXXXXMVPSVEKKIAELEIGLLHLQQNIEIPEITLTPHPYVAHIIQEKLLQNKEARVSDFEDKFEDTQFLNQLQAGVNRWIKEIQKVTKLNRDPSTGTALQEISFWLNLEHSLDKIQEKRESLEVALTLAILKQAKRFHATTSFDTDTALSSAKIQVKDYNQLMKDFPINDLLSASQLDKISEALQQIFSHLKKVRATKYPVNRIIKLMEALSRDLTTQLMKVISNMHLMSMPYDEFEKIFTACQQVFSTWEDEYDKMQNLLRDIAKKKREEFTKFAWKMNATHKKLQTRLENIKKFRYQHEQLRQVIVRVLKPVTKVVPSVEAGVPKDQIT----------------DKGDKSSTFLPESADTSSIDEVNAAYEIVKVIDCLDFAKEENDEWDAAIKRYEERIDRVESRIASHLRDLLGQSKNANEMFRYFSRFNALFVRPHIRGAIGEYQTQLIQRVKDDIEALHNKFKVQYASSTACKMSKVRDLPPVSGSIIWVRQILRQLNAYMKRVEDVLGKDWAQHIEGQKLKADGESFKLKLNTSELFEEWSKKVAEKSLSVAGSIFNVESTRTVVTVRDREPQKITVLKLKVNFLPDVITLAKEVRNMRALGFRTPLSIVNKAHSANQLYPFAISLIESVRTYESTCSKIEEHKMQNISLLTAGLRKDVQLCIHEGVQITWESYRLDQYVQKLAELVFSFQEKVDDLVIVIKEIDFNVKALETCSYNKQTFEEILIRIQEAVDNMSLHQFSNLAQWVSNLDSLVEQRLIVRLEAGLLEWIKVLKGXXXXXXXXXXXXXXXVNSMAKHRLGGKPQIKKLIHELRITNQQMHLYPSIEVATQDILYQMSSWQNIILNLSRIVHSRYQVGLETESDNQKTYKKLLSSLPNSGESLENAYAAVHNILRDANEYVKTWTNYQSLWDLQGDQLFSLIADDNTVWMNVLEEIKSMRKHFDVAETQKEFGPLVIAFGKVQSKVSMKYDNWHKEVLTKFGQNMGKMMTTLYNEVQRARNELEQQSIDSGGTNESVNFITYTQNIKRKMNTWEKQAEACRAGQNILCRDRFQFPNDWLDSENIQGEWSAFKEIMRRKQETISSQVASLQMKITEEDKIVESKTTEVLGNWEKDKPIAGDLTPEEAVNIIQILEGKFNRLKEERENVQKAKEALELTEIGVKPISEEKVTNALSELHDLKNVWNELKSIWEKIRDMKETPWLSVQPRKLRQDIENLTAQLKELPNSFKQYASFEHVRTLLKMYMKVNASIVELKSEAIKERHWRMLMRKLNVSWSLNELQLGKVWDIDLVKNEEIIREVLAIAQGEKALEEYLRQITEVWKNYVLELTNYQSKSKIIKGWDDLFNKVKEHINNVTSMKASPYFKQFEEEATAWEDRLNKINALFDVWIDVQRRWIYLDGIFAGSADIKVLLPVESQRFQSVSTEFLGLMKKVQKSPLVTDVLNIANVQRQLERLADLLGKIQKSLGEYLERQRSSFPRFYFVGDEDLLEIIGNSXXXXXXXXXXXXMFAGVHSIILSEDEKVILGMMSKEGEELRFISPVSIIEHPRINDWLTAMEKEMRVSLAKYLNVAVKEISGWRTESNIDKDKFMVWLDKYQAQIVVLAAQITWSEAVEASLA---------SGVSLESTMTVVHSTLNMLADTVLYEQPPVRRRKLEHLIIEYVHQRDVLRALHNDGVSSNKNFDWMSQMRFYFDPKQTDPLHQLSIHVANAKFHYGFEYLGVCDRLVQTPLTDRCYLTMTQALEARLGGSPFGPAGTGKTESVKSLGNQLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLSAVSQQIQGIQEALRELM----VSKKDSINVELLGKQVHVNPDMAIFITMNPGYAGRSNLPDNLKKLFRSLAMTQPDRQLIAQVMLYSQGFRTAEVLAGKVVPFFKLCDEQLSPQSHYDFGLRALKSVLVSAGNVKRDRIKQEKEKIVARGEEINETAIAEQLPEQEILIQSVMETMVPKLIADDIPLLYSLLTDVFPGVEYRQAEMKRLREELRKVSENKFLVYSD----------EPN------TAGYLWVEKVLQLYQITTIHHGLMMVGPSGSGKTMACRVLLQALENIDGIEGVAHIIDPKSISKDSLYGYMDPNTREWTDGLFTHILRRIIDSVRGESNKRQWIVFDGDVDPEWVENLNSVLDDNKLLTLPNGERLAIPPNVRIMFEVQDLKYATLATVSRCGMVWFSEEVLTTGMILTHFLNELKKVQVMEGEEDFSVNQG------------------DTGADADSKISSSPIIQLQTQVSSILAPFFTEDGLIAKCLDYSTTLEHIMDFTRLRALTSLFSMIKQSIRNMIEYNQSHSDFPLNNEQIENYVAKSLISSVVWSMSGDSKLKVREQLSQYIKNISTVDLPTVGGIKNIIDFEVNIQGTWVAWSNKVPQIEVETHKITATDVVVPTMDTVRHEALLYTWLAEHRPVLLCGPPGSGKTMTLFSALRCLPDMEVVGLNFSSATTPELMLKTFDQYCEYRKTPNGIVLAPQQLNKWLIFFCDEINLPDMDKYGTQRVISFLRQMVEHHGFYRITDMQWVSFERIQFVGACNPPTDPGRKPLSHRFLRHVPVVYVDYPGETSLKQIYSTFNRAMLRMLPSLRGYADTLTNAMVEFFLKTQERFTHDMQPHYIYSPREMTRWVRGIHEALKPLESLSVEGLVRIWAHEALRLFQDRLVEEDERHWTDDNINEVALKHFPNINKEEALKRPILYSNWLSKDYSAVTQEELRDYVKARLKVFYEEELDVPLVLFNQVLDHVLRIDRVFRQPQGHLLLIGVSGAGKTTLSRFVSWINGLSVFQVKVHNKYTAEDFDEDLRNVLRRSGCKGEKITFIMDESNVMDSSFLERMNTLLANGEVPGLFEGDELTTLMTQCKEGAIREGLMIDSQEELYKWFTQQICRNLHVVFTMNPSADGLKDKASTSPALFNRCVLNWFGDWSLEAYFQVGKEFTNRLDLERTDYKVPDTLPCIAEGLLPQNPIYRDVVVNALVFVHQTMHQANVRVQKRGGRTAAITPRHYLDLIAHYMKLSAEKRADLEEQQLHLNNGLKKIEQTVDQVEVMQRSLTKKRQELENMNEAANAKLKQMVQDQQEAEQKKTTGQALKEELAKQEQFVNEKQKTVKQELDQVEPTVNEAKQAVQNIRKKDIQEIKAMKNPPNAVKMAVESICLLLGEKTTDWQSILKVIIKDTFVTSILNFNTDDVSDNTRETMKKKYLSNPDYNFEKVNKASNACGPMVKWVLAQISYADILKRVEPLRNELTELSDAAEQNRKKSQETEDLIAQLEKSIAKYTEEYATLISQAQTIKSDLASVESKVGRSVALLGSLSSERTRWDSGSETFKAQMATINGDCLLSSAFMAYGGYFDQHMRTSLFNTWCHHLSEADILFRSDLARVEYLSNPDDRLRWQANSLPADDLCVENAIILRRYNRYPLIIDPSGQATTFLLNEYKEKKITKTSFLDDSFRKTLESALRFGTPLLVQDVESYDPILNPVLNREVRRTGGRTLITLGDQDIDLSPTFTIFLSTRDPSVEFAPDICSRVTFVNFTVTRSSLQNQCLNAVLKIERPDIDQKRSDLLKAQGEFQLKLRHLEKDLLQSLNEAQGNLLENDKIIARLETLKREAADVAKKVEETDVVMQEVESVSTEYVPLAQSCSNIYFTLEAMNQIHFLYQYSLQLMLDIFSSVLINNPELTNVKAASDRLKIITKNLFQVTYNRLARGMLHEDQITFATILARIFLKG--STPIGFLENEFQHFLRSQEATITSSDSNKQDNLGLTLHQDQ-IDSVKRLKKLKVFAKIEEKVKSTK-DIKNWTLTVTPESNVPELW--VDDNNYNDEKLSKIAKGMYNLLIIQAIRPDRLLASTQKFIASVLGDTFTESVRGTLDLASIVEVEVTACVPILLCAVQGYDPSGRVEDLASEQGKQLTGIAIGSAEGFSQAEKAINSAAKTGKWVMLKNVHLATSWLVSLEKKIHSLQAHPNFRLFLTMEITPKLPVNLLRAGRVLVFEPPPGIKANLLRTLSSINNQRMSKEPVERSRLYFLLAWLNAIVQERLRYVPLGYSKKYEFGESDFKCALDTIDTWVDGAAMGRTNLPPEKIPWVALQTLLGSCIYGGKIDNAFDQRLLNSFLGYLFTEKCFDHNFALVSDADD--GSNIAFPESTKHTDILQWVHKLPDLQTPSWLGLPNSAEKVLLTNLGQSLIGNILKMQQSLEDDEELVVGQSKTKRTIEVGDGRPAWMRQLYQSTQTWLQILPKSVTPLQRTIENIKDPMYRCFEREVNSGCNLLASVRKDLEDVAEVCKGAKKPTNHHRSMMADLAKGIIPKMWIRYAIPPGLTVIQWIQDFADRIKQLLHISDTAAKSGVIALRSIQVWLGGLFMAEAYITATRQSVAQNNKWALEELFLDVEL---GE-----GKVDSNTCVITGLRLMGSEIVDPRTLKLSTLIYKDIDICRLKWIRVEKSQQLEGSSAK-DKVCLPIYLNAARSTVLFTLYFSTTDSSYDFYKRGVAI 14048 MAD + P Q ++ P + C+L +D+ + L +P + + KFI+D Q+ +L +Q+ K ++E+G+E + + +V F S+K Q+ +FIK V+EADK+ S QL+ L++ DG P+ET+HS++ + P++KSYI++ G+ M PSVEK + ELE+GLLHLQQNI+IPEITL+ HP VA ++++K A+ SDFEDK ED FLN LQ+GVNRWIKEIQKVTKL RDP++GTALQEI+FWLNLE SL +IQEKRESLEV LTL ILK AKRFHA SF+ DT L A V DYN LMKDFP+NDLL+A++LD+I A+Q IF+HL+K+R TKYPV R ++L++A+S DL++QL+KV+ LM MP++EFE++ AC +VF+TW+DE D++Q LLRDI KKKREE + W+ H++LQ RL++++KFR+QHEQLRQVI+RVL+P V +AG KD++ DK + L +++D ++I+EVN AYEIVK IDCLD KE D W+AA+KRY+ERIDRVE+RIA+ LRDLLG +KNANEMFRYFSRFNALFVRPHIRGAI EYQTQLIQRVKDDIEALH KFK QY+SS A M+K RDLPPV+GSIIW RQI RQLNAY+ RVEDVLGK W H +GQ LK +GESFK KLNT+E+FE W +KV++K + V+G IFN+E R + ++ E Q +TVLKL+VNF P+V TLAKEVRNM+ LGFR PL IVN+AH NQLYPFA+SLIESVRTYESTC KIEEH+ QNI LL AGLR+D QL I EG+ + WESYRL YVQK +E + FQEKVDDL+ +EID VK+LETC Y+K FEEI+ +IQ+AVD ++LHQ+SNL QWVS LD VE+RL+VRLEAG+ EW + L+GE E E DD D + +K+ LGG+P++K ++HELRITNQQMHL+PSIEVA Q++L + SW+ I+LNL RI HSRYQVGLE D K YKK+L +L + E+LE A+ A+ +++ +A EYVKTWT+YQ+LWDLQ DQ++ I D VWMNVL+EIKSMR+HFDVAE+QKEFGP+VI FGKVQSKVS+KYDNWHK++L+KFG ++G M LYNEV +AR ++EQQ++++G T+E+VN ITY Q +KRKM WEKQ E R GQNIL RDRFQFP+ WLDSENI GEWSAF+EI+RRK+ ISSQVASLQMK+ EDK+VESKTTE+L NWEK+KP+ GD+ PEEAV+++ ILEGKF RL+EEREN+Q+AKEALELTE GV SE++V A+ EL DLKNVW EL +WE+I +KETPW +VQPRKLRQ ++ + Q+KELP +QYAS+EHV+ L+ Y KVN +VELKSEA+KERHW+MLM+KLNV W+++EL LG VWDIDL KN+ IIREVL IAQGEKALEE+L+Q+TE WKNY L+L +YQ+K ++I+GWDDLF +VKE IN++T+MK SPYFKQFEEEA AWEDRLN+INALFDVWIDVQRRW+YLDGIFAGSADIK+LLP ESQRFQSVSTEFLGLMKKV KSPLV DVLNI+ V RQLERLADLL KIQ+SLGEYLERQRSSFPRFYFVGDEDLLEIIGNSK++ +LQKHFKKMFAGVHSI L+ED +LG+ SKEGEE+ FI PVSI ++P INDWLT +E+EMRVSLA YL A++++ R +++K F+ WLD++ AQ+VVLAAQ+ WSE+V+A+LA S L + V + L +LAD+VLYEQPPVRRRKLEHLIIE+VHQRDV+R L + +S+++FDW+SQMRFYFDPKQTDPLHQ+SI +AN KF YGFEYLGV DRLVQTPLTDRCYLT+TQALE RLGGSPFGPAGTGKTESVK+LG QLGRFVLVFNCDETFDF AMGRIFVGLCQVGAWGCFDEFNRLEERMLSAVSQQIQ IQE LR++ + KD + VELLGKQV V+PDMAIFITMNP YAGRSNLPDNLKKLFRSLAMTQPDRQLIAQVMLYSQGFRTAEVLA K+VPFF+LCDEQLS QSHYDFGLRALKSVLVS+GNVKR+RI++ K+ I+ARGE +NE++IAEQLPEQEILIQSVMETMVPKL+A+DIPLLYSLLTDVFPGV Y + M+ LR ELR+V +LVY++ E N TAG LWV+KVLQLYQIT IHHGLMMVGPSGSGK+MA R LL+ALE ++GIEGVAH+IDPKSI+K+SLYGY+DPNTREWTDGLFTHILR+IIDS+RGES KRQWI+FDGDVDPEWVENLNSVLDDN+LLTLPNGERL IPPNVRIMFEVQDL+YATLATVSRCGMVWFSE+V+ + + HF+ +L+ V + EGEE+ +V G D + SP ++LQ V+SIL P F + GL+++CL Y+ L+HIMDF LR+LTSLFS++KQ IRN++ YN +HSDFP++ +QIE+YV+KSLI +++WSM GD +L RE+L Y++ I+T+ LP G IID+EV + G W AWS KVP IEVETHKIT+ DVVVPTMDTVRHEALLY WLAEHRP++LCGPPGSGKTMTLFSALR LPDMEVVGLNFSSATTPELM+KTFDQYCE RKTPNG+VLAP QLNKWL+FFCDEINLP+ DKYGTQRVISFLRQMVEH GFYR +DMQW+ FERIQFVGACNPPTDPGRKPLSHRFLRHVPVVYVDYPGE SLKQIY TFNRAMLR+LPSLR AD LTNAMV+FFL +Q+RFT DMQPHYIYSPRE++RWVRGIHEALKPL+SLSVEGLVRIWAHEALRLFQDRL+EE ER WTD +I++VALK+FP+I+KE AL RPIL+SNWLSK+Y +V QE LRDYVKARLKVFYEEELDVPLVLFNQVLDHVLRIDRVFRQPQGHLLLIG+SGAGKTTLSRFVSWINGLSVFQVKVHNKYTAEDFD+DLRNVLRR+GCKGEKITFIMDESNV+DSSFLER+NTLLANGEVPGLFEGDE LMTQCKEGA R+GLM+DS EELYKWFT QIC NLHVVFTMNPS DGLKD+ASTSPALFNRCVLNWFGDWS+EAYFQVG+EFT++ D+ER DYKVPD +P +AE LLP+ P +R++V NA VFVH T+H+AN R+QKR GR+ +TPRH+LD IAH++KL EKR+DLEEQQLHL GL+KI +TV+QVEVMQ+SLT+KRQELE MNEAANAKLKQMV DQQEAE++KT Q L+EELA QE F+NEK+ V EL QVEP VN+AKQAV IRK+DIQE+KAMKNPP VK+A+ESIC LLGE +TDW+ IL I+KDTFV SILNFNTDD++D+ RETMKKKYL+NPDYNF+KVN+AS+ACGPMVKW +AQ+ YADILK VEPLRNEL L AA +N+++++ E I LE+SIAKY EEYA LISQAQ IKSDLA+VE+KV RSVAL+ SLSSER+RW+SG+ETFK+QM+TI GDCLLS+AFMAYGGYFDQH+R SLF TWC HL DI FRSDLA VEYLSNPD+RLRWQAN LP D+LCVENAI+L R+NRYPLIIDPSGQAT FLLNEYK KKI KTSFLDD+FRKTLESALRFGTPLLVQDVESYDPILNPVLNREVRRTGGRTLIT+GDQDIDLSPTF+IFLSTRDPSV+F PD+CSRVTFVNFTVTR SLQ QCLNAVLK ERPD+D KRSDLLK QGEFQL+LRHLEKDLLQSLNEA+GNLL++DKII RLETLK+EAA+VAKKVEETDV+M EVE+VS +YVPLAQSCS IYFTLEAMNQ+HFLYQYSLQ +LD+F+ VL N L +V+ + RLKIIT++LFQVTYNR+ARGMLH DQITFA +LARIFLKG ++ L+ EF FLR Q+ I ++ + + Q + ID +K KKL F ++ + + W +V PE+NVP LW ++ +Y+LL+IQA RPDRLLAS + +++ LG+TF + RG LDL SIVE E+ + +PILLCAVQG+DPSGRVED+ASE KQLT IAIGSAEGFSQA+KAINSAAK+GKWVMLKNVHLA WLV LEKK+HS+Q HPNFRLFLTMEI PKLPVNLLRAGR VFEPPPGIK++LLRT +S+ R+SK P ERSRLYFLLAW NA+VQERLRYVPLG+SK+YEF ESD K A DTIDTWVD AAMGRTNLPPEK+PW AL+TLLG IYGGKIDN+FDQRL+ +FL LFTE F+H+F LV D D G +I PE + D+L W++KLPD+QTPSWLGLPN+AEKVLLTNLGQ + GN+LK+Q++ DDE L + K++ V D RP WMRQL S WL LPK+V L RT+EN++DP+YR FEREVNSG NLLASVR+DLE ++ VC G +KPTN +R MM+DL KG+IP W +Y +P +TVIQWI DF R+KQL+ IS+ AA GV ALR IQ+WLGGLFM EAYITATRQ VAQ+N WALEEL+LDV+L G+ G S + L LMG+E +D TL LS I D+ + LKWIR+ +Q E K V LP+Y+N ARS VLFTL ST + S FY+RGVA+ Sbjct: 1 MADSGGDAPPVPAQPTATLADPSALSQYLFKTVSCILEEDDDGAVI-LRSVLEDPTGRDAIKKFISDPQIHSLIVQKLSNKDDDEDGAESGISYSVLTDVRFASSKVQSMVFIKRGAVLEADKSFSVQLRFLNFTDGSPYETLHSMISDAISPFYKSYIRESGRADRDGDK-MAPSVEKTMTELEMGLLHLQQNIDIPEITLSIHPVVAQVVKQKAEAGLRAKASDFEDKMEDAHFLNALQSGVNRWIKEIQKVTKLERDPASGTALQEITFWLNLERSLFRIQEKRESLEVTLTLDILKHAKRFHALVSFEHDTGLQQALDTVNDYNPLMKDFPLNDLLAATELDEIRLAIQSIFTHLRKIRNTKYPVQRALRLVQAISNDLSSQLLKVLGTRRLMHMPFEEFERVMGACSKVFATWDDESDRLQGLLRDIIKKKREEQLRIGWRGAPAHRRLQIRLDHMRKFRHQHEQLRQVIMRVLRPAQTRVTHTDAG--KDELAGNQPGENSSAETTKGPDKISRKVQPLLDASDANAIEEVNLAYEIVKEIDCLDVTKEGTDAWEAAVKRYDERIDRVETRIAARLRDLLGTAKNANEMFRYFSRFNALFVRPHIRGAIREYQTQLIQRVKDDIEALHTKFKAQYSSSEAYHMTKCRDLPPVAGSIIWARQIERQLNAYLHRVEDVLGKGWEHHRDGQLLKTEGESFKAKLNTTEVFEAWVRKVSQKQVLVSGRIFNIEPIRARIATKEGETQTVTVLKLRVNFQPEVNTLAKEVRNMKWLGFRVPLGIVNQAHQTNQLYPFAVSLIESVRTYESTCIKIEEHQRQNIGLLCAGLRRDAQLFILEGMNLIWESYRLGVYVQKFSENMLQFQEKVDDLLQTTREIDLQVKSLETCVYSKAVFEEIIGKIQKAVDELNLHQYSNLPQWVSRLDEEVERRLVVRLEAGVREWTRALRGEKSEAENDDDAQDTHSSQQSKNPLGGEPKLKMIVHELRITNQQMHLHPSIEVAQQELLLSLGSWEGIVLNLPRIQHSRYQVGLEVGGDVHKNYKKILHNLDRADEALEQAHQAILDVVSEAREYVKTWTSYQALWDLQSDQVYGRIGTDTRVWMNVLDEIKSMRQHFDVAESQKEFGPIVIMFGKVQSKVSLKYDNWHKDILSKFGNHLGTEMQELYNEVSKARLDMEQQTVEAGSTSEAVNAITYAQAVKRKMKAWEKQVELYRTGQNILYRDRFQFPSGWLDSENILGEWSAFQEILRRKETAISSQVASLQMKVVAEDKVVESKTTELLLNWEKEKPVEGDIKPEEAVSLLTILEGKFIRLREERENIQRAKEALELTEFGVASPSEQRVQVAIEELQDLKNVWLELSRVWEQIETLKETPWQTVQPRKLRQQLDTMANQIKELPTRLRQYASYEHVKRTLQSYAKVNVLVVELKSEALKERHWKMLMKKLNVDWTMSELTLGHVWDIDLQKNDSIIREVLLIAQGEKALEEFLKQVTEEWKNYTLDLISYQNKCRLIRGWDDLFTRVKERINSLTAMKMSPYFKQFEEEALAWEDRLNRINALFDVWIDVQRRWVYLDGIFAGSADIKILLPQESQRFQSVSTEFLGLMKKVAKSPLVMDVLNISKVDRQLERLADLLSKIQRSLGEYLERQRSSFPRFYFVGDEDLLEIIGNSKNVPRLQKHFKKMFAGVHSIKLNEDSTEVLGLCSKEGEEVIFIKPVSIKDNPVINDWLTLLEREMRVSLATYLAKAIQDLQKLRASGDLEKSGFLDWLDRFHAQLVVLAAQVIWSESVDAALAAMDGKASKGSESPLHKCLASVENMLTVLADSVLYEQPPVRRRKLEHLIIEHVHQRDVIRTLIQNNANSSRSFDWLSQMRFYFDPKQTDPLHQVSIQMANTKFQYGFEYLGVIDRLVQTPLTDRCYLTLTQALEGRLGGSPFGPAGTGKTESVKALGTQLGRFVLVFNCDETFDFHAMGRIFVGLCQVGAWGCFDEFNRLEERMLSAVSQQIQSIQETLRDMACGAKTAGKDGVTVELLGKQVTVHPDMAIFITMNPDYAGRSNLPDNLKKLFRSLAMTQPDRQLIAQVMLYSQGFRTAEVLASKIVPFFQLCDEQLSAQSHYDFGLRALKSVLVSSGNVKRERIRRIKDDILARGETVNESSIAEQLPEQEILIQSVMETMVPKLVAEDIPLLYSLLTDVFPGVVYSPSAMEGLRRELRRVCNETYLVYNESGLFHEAAGHESNSNIFGTTAGSLWVQKVLQLYQITCIHHGLMMVGPSGSGKSMAWRTLLKALERLEGIEGVAHVIDPKSINKESLYGYLDPNTREWTDGLFTHILRKIIDSIRGESLKRQWIIFDGDVDPEWVENLNSVLDDNRLLTLPNGERLGIPPNVRIMFEVQDLRYATLATVSRCGMVWFSEDVIPPELAMEHFIRQLQNVPIDEGEEE-TVGFGLPVVTPESSDQVQSPDFQDLPGVSRESGPVSPTLRLQCDVASILQPHFADGGLVSRCLAYAKDLDHIMDFMPLRSLTSLFSIMKQCIRNIMAYNMTHSDFPMSADQIESYVSKSLIYAIIWSMCGDGRLSTREELGNYLREITTIPLPPTGA--PIIDYEVKLNGEWQAWSQKVPVIEVETHKITSMDVVVPTMDTVRHEALLYLWLAEHRPMILCGPPGSGKTMTLFSALRSLPDMEVVGLNFSSATTPELMMKTFDQYCECRKTPNGLVLAPVQLNKWLVFFCDEINLPNEDKYGTQRVISFLRQMVEHGGFYRTSDMQWLKFERIQFVGACNPPTDPGRKPLSHRFLRHVPVVYVDYPGELSLKQIYGTFNRAMLRLLPSLRSQADALTNAMVDFFLLSQKRFTQDMQPHYIYSPRELSRWVRGIHEALKPLDSLSVEGLVRIWAHEALRLFQDRLIEETERQWTDAHIDDVALKYFPSIDKEAALSRPILFSNWLSKEYCSVEQETLRDYVKARLKVFYEEELDVPLVLFNQVLDHVLRIDRVFRQPQGHLLLIGISGAGKTTLSRFVSWINGLSVFQVKVHNKYTAEDFDDDLRNVLRRAGCKGEKITFIMDESNVLDSSFLERINTLLANGEVPGLFEGDEFAALMTQCKEGATRDGLMVDSHEELYKWFTNQICTNLHVVFTMNPSEDGLKDRASTSPALFNRCVLNWFGDWSIEAYFQVGREFTSKTDMERPDYKVPDFVPAVAEHLLPECPSFREMVANAFVFVHTTLHRANARLQKRTGRSMWVTPRHFLDFIAHFVKLMTEKRSDLEEQQLHLQIGLQKINETVEQVEVMQKSLTQKRQELEQMNEAANAKLKQMVHDQQEAEKRKTMSQRLQEELASQEVFINEKRTLVMNELSQVEPAVNDAKQAVSEIRKRDIQELKAMKNPPATVKLAIESICFLLGEYSTDWRQILTTIMKDTFVPSILNFNTDDITDSIRETMKKKYLNNPDYNFDKVNRASSACGPMVKWAIAQVQYADILKNVEPLRNELKALEQAASKNKEEAKNVESTIESLERSIAKYKEEYAVLISQAQAIKSDLATVEAKVERSVALIKSLSSERSRWESGAETFKSQMSTIFGDCLLSAAFMAYGGYFDQHLRASLFATWCQHLQSVDIRFRSDLALVEYLSNPDERLRWQANDLPNDELCVENAIMLTRFNRYPLIIDPSGQATEFLLNEYKAKKIMKTSFLDDAFRKTLESALRFGTPLLVQDVESYDPILNPVLNREVRRTGGRTLITIGDQDIDLSPTFSIFLSTRDPSVDFPPDVCSRVTFVNFTVTRGSLQTQCLNAVLKAERPDVDSKRSDLLKMQGEFQLRLRHLEKDLLQSLNEAEGNLLDDDKIITRLETLKQEAAEVAKKVEETDVIMSEVETVSQQYVPLAQSCSAIYFTLEAMNQVHFLYQYSLQFLLDVFTCVLTQNARLKDVRESVQRLKIITQDLFQVTYNRVARGMLHNDQITFAVLLARIFLKGQANSKSLSLDTEFDCFLRGQD--IMPKETISKGSASADAEQTRMIDVLK--KKLPSFRNLDSAIAQNRAAFSAWISSVAPEANVPVLWEPTKTEGPTPSWFTQAQTSIYHLLLIQAFRPDRLLASAHRLVSAALGETFMDEARGHLDLLSIVEQEIRSNMPILLCAVQGFDPSGRVEDMASEHHKQLTNIAIGSAEGFSQADKAINSAAKSGKWVMLKNVHLAPGWLVQLEKKLHSVQPHPNFRLFLTMEINPKLPVNLLRAGRAFVFEPPPGIKSSLLRTFASVPAARISKTPAERSRLYFLLAWFNAVVQERLRYVPLGWSKRYEFNESDLKVACDTIDTWVDSAAMGRTNLPPEKVPWAALRTLLGQSIYGGKIDNSFDQRLMETFLSVLFTEASFEHDFPLVRDVDGNAGKHILVPEGSSRDDLLAWINKLPDVQTPSWLGLPNNAEKVLLTNLGQVMTGNLLKLQEAAADDESLPISAFDRKKSSVVSDARPPWMRQLLGSASAWLSSLPKTVKRLTRTVENLRDPLYRFFEREVNSGSNLLASVRQDLEVISAVCAGERKPTNRYRLMMSDLVKGLIPNDWRQYNVPKTMTVIQWISDFGLRVKQLVAISEAAATGGVSALRDIQIWLGGLFMPEAYITATRQFVAQSNGWALEELYLDVQLVLQGKGGKMTGSSTSGAFTVRDLTLMGAEPLDESTLHLSDTISVDLPLTVLKWIRLSADEQAERYVEKPGSVRLPVYMNGARSLVLFTLRLSTKERSNRFYERGVAL 4725
BLAST of Cytoplasmic dynein 1 heavy chain 1 vs. TrEMBL
Match: A0A3R7H766 (Cytoplasmic dynein 1 heavy chain 1 OS=Clonorchis sinensis OX=79923 GN=DYNC1H1 PE=4 SV=1) HSP 1 Score: 6648.15 bits (17247), Expect = 0.000e+0 Identity = 3212/4747 (67.66%), Postives = 3823/4747 (80.54%), Query Frame = 3 Query: 87 MADITANLVQPPDQEITAISLPKFIKYLTLYAFPCMLNDDESKSRKDYELFLSEPQNEECLTKFINDNQVTTLTIQQ--TKRXXXXXXXXXXXXKISNEVNFESNKSQTSIFIKNNQVIEADKTISSQLQVLSYCDGPPFETMHSLVCYGLLPYFXXXXXXXXXXXXXXXXXMVPSVEKKIAELEIGLLHLQQNIEIPEITLTPHPYVAHIIQEKLLQNKEARVSDFEDKFEDTQFLNQLQAGVNRWIKEIQKVTKLNRDPSTGTALQEISFWLNLEHSLDKIQEKRESLEVALTLAILKQAKRFHATTSFDTDTALSSAKIQVKDYNQLMKDFPINDLLSASQLDKISEALQQIFSHLKKVRATKYPVNRIIKLMEALSRDLTTQLMKVISNMHLMSMPYDEFEKIFTACQQVFSTWEDEYDKMQNLLRDIAKKKREEFTKFAWKMNATHKKLQTRLENIKKFRYQHEQLRQVIVRVLKPVTKVVPSVEAGVPKDQIT----------------DKGDKSSTFLPESADTSSIDEVNAAYEIVKVIDCLDFAKEENDEWDAAIKRYEERIDRVESRIASHLRDLLGQSKNANEMFRYFSRFNALFVRPHIRGAIGEYQTQLIQRVKDDIEALHNKFKVQYASSTACKMSKVRDLPPVSGSIIWVRQILRQLNAYMKRVEDVLGKDWAQHIEGQKLKADGESFKLKLNTSELFEEWSKKVAEKSLSVAGSIFNVESTRTVVTVRDREPQKITVLKLKVNFLPDVITLAKEVRNMRALGFRTPLSIVNKAHSANQLYPFAISLIESVRTYESTCSKIEEHKMQNISLLTAGLRKDVQLCIHEGVQITWESYRLDQYVQKLAELVFSFQEKVDDLVIVIKEIDFNVKALETCSYNKQTFEEILIRIQEAVDNMSLHQFSNLAQWVSNLDSLVEQRLIVRLEAGLLEWIKVLKGXXXXXXXXXXXXXXXVNSMAKHRLGGKPQIKKLIHELRITNQQMHLYPSIEVATQDILYQMSSWQNIILNLSRIVHSRYQVGLETESDNQKTYKKLLSSLPNSGESLENAYAAVHNILRDANEYVKTWTNYQSLWDLQGDQLFSLIADDNTVWMNVLEEIKSMRKHFDVAETQKEFGPLVIAFGKVQSKVSMKYDNWHKEVLTKFGQNMGKMMTTLYNEVQRARNELEQQSIDSGGTNESVNFITYTQNIKRKMNTWEKQAEACRAGQNILCRDRFQFPNDWLDSENIQGEWSAFKEIMRRKQETISSQVASLQMKITEEDKIVESKTTEVLGNWEKDKPIAGDLTPEEAVNIIQILEGKFNRLKEERENVQKAKEALELTEIGVKPISEEKVTNALSELHDLKNVWNELKSIWEKIRDMKETPWLSVQPRKLRQDIENLTAQLKELPNSFKQYASFEHVRTLLKMYMKVNASIVELKSEAIKERHWRMLMRKLNVSWSLNELQLGKVWDIDLVKNEEIIREVLAIAQGEKALEEYLRQITEVWKNYVLELTNYQSKSKIIKGWDDLFNKVKEHINNVTSMKASPYFKQFEEEATAWEDRLNKINALFDVWIDVQRRWIYLDGIFAGSADIKVLLPVESQRFQSVSTEFLGLMKKVQKSPLVTDVLNIANVQRQLERLADLLGKIQKSLGEYLERQRSSFPRFYFVGDEDLLEIIGNSXXXXXXXXXXXXMFAGVHSIILSEDEKVILGMMSKEGEELRFISPVSIIEHPRINDWLTAMEKEMRVSLAKYLNVAVKEIS-----------GWRTESNIDKDKFMVWLDKYQAQIVVLAAQITWSEAVEASLAS---------GVSLESTMTVVHSTLNMLADTVLYEQPPVRRRKLEHLIIEYVHQRDVLRALHNDGVSSNKNFDWMSQMRFYFDPKQTDPLHQLSIHVANAKFHYGFEYLGVCDRLVQTPLTDRCYLTMTQALEARLGGSPFGPAGTGKTESVKSLGNQLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLSAVSQQIQGIQEALRELM----VSKKDSINVELLGKQVHVNPDMAIFITMNPGYAGRSNLPDNLKKLFRSLAMTQPDRQLIAQVMLYSQGFRTAEVLAGKVVPFFKLCDEQLSPQSHYDFGLRALKSVLVSAGNVKRDRIKQEKEKIVARGEEINETAIAEQLPEQEILIQSVMETMVPKLIADDIPLLYSLLTDVFPGVEYRQAEMKRLREELRKVSENKFLVYSD----------EPN------TAGYLWVEKVLQLYQITTIHHGLMMVGPSGSGKTMACRVLLQALENIDGIEGVAHIIDPKSISKDSLYGYMDPNTREWTDGLFTHILRRIIDSVRGESNKRQWIVFDGDVDPEWVENLNSVLDDNKLLTLPNGERLAIPPNVRIMFEVQDLKYATLATVSRCGMVWFSEEVLTTGMILTHFLNELKKVQVMEGEED---FSVN---------------QGDTGADADSKISSSPIIQLQTQVSSILAPFFTEDGLIAKCLDYSTTLEHIMDFTRLRALTSLFSMIKQSIRNMIEYNQSHSDFPLNNEQIENYVAKSLISSVVWSMSGDSKLKVREQLSQYIKNISTVDLPTVGGIKNIIDFEVNIQGTWVAWSNKVPQIEVETHKITATDVVVPTMDTVRHEALLYTWLAEHRPVLLCGPPGSGKTMTLFSALRCLPDMEVVGLNFSSATTPELMLKTFDQYCEYRKTPNGIVLAPQQLNKWLIFFCDEINLPDMDKYGTQRVISFLRQMVEHHGFYRITDMQWVSFERIQFVGACNPPTDPGRKPLSHRFLRHVPVVYVDYPGETSLKQIYSTFNRAMLRMLPSLRGYADTLTNAMVEFFLKTQERFTHDMQPHYIYSPREMTRWVRGIHEALKPLESLSVEGLVRIWAHEALRLFQDRLVEEDERHWTDDNINEVALKHFPNINKEEALKRPILYSNWLSKDYSAVTQEELRDYVKARLKVFYEEELDVPLVLFNQVLDHVLRIDRVFRQPQGHLLLIGVSGAGKTTLSRFVSWINGLSVFQVKVHNKYTAEDFDEDLRNVLRRSGCKGEKITFIMDESNVMDSSFLERMNTLLANGEVPGLFEGDELTTLMTQCKEGAIREGLMIDSQEELYKWFTQQICRNLHVVFTMNPSADGLKDKASTSPALFNRCVLNWFGDWSLEAYFQVGKEFTNRLDLERTDYKVPDTLPCIAEGLLPQNPIYRDVVVNALVFVHQTMHQANVRVQKRGGRTAAITPRHYLDLIAHYMKLSAEKRADLEEQQLHLNNGLKKIEQTVDQVEVMQRSLTKKRQELENMNEAANAKLKQMVQDQQEAEQKKTTGQALKEELAKQEQFVNEKQKTVKQELDQVEPTVNEAKQAVQNIRKKDIQEIKAMKNPPNAVKMAVESICLLLGEKTTDWQSILKVIIKDTFVTSILNFNTDDVSDNTRETMKKKYLSNPDYNFEKVNKASNACGPMVKWVLAQISYADILKRVEPLRNELTELSDAAEQNRKKSQETEDLIAQLEKSIAKYTEEYATLISQAQTIKSDLASVESKVGRSVALLGSLSSERTRWDSGSETFKAQMATINGDCLLSSAFMAYGGYFDQHMRTSLFNTWCHHLSEADILFRSDLARVEYLSNPDDRLRWQANSLPADDLCVENAIILRRYNRYPLIIDPSGQATTFLLNEYKEKKITKTSFLDDSFRKTLESALRFGTPLLVQDVESYDPILNPVLNREVRRTGGRTLITLGDQDIDLSPTFTIFLSTRDPSVEFAPDICSRVTFVNFTVTRSSLQNQCLNAVLKIERPDIDQKRSDLLKAQGEFQLKLRHLEKDLLQSLNEAQGNLLENDKIIARLETLKREAADVAKKVEETDVVMQEVESVSTEYVPLAQSCSNIYFTLEAMNQIHFLYQYSLQLMLDIFSSVLINNPELTNVKAASDRLKIITKNLFQVTYNRLARGMLHEDQITFATILARIFLKG--STPIGFLENEFQHFLRSQEATITSSDSNKQDNLGLTLHQDQ-IDSVKRLKKLKVFAKIEEKVKSTK-DIKNWTLTVTPESNVPELW--VDDNNYNDEKLSKIAKGMYNLLIIQAIRPDRLLASTQKFIASVLGDTFTESVRGTLDLASIVEVEVTACVPILLCAVQGYDPSGRVEDLASEQGKQLTGIAIGSAEGFSQAEKAINSAAKTGKWVMLKNVHLATSWLVSLEKKIHSLQAHPNFRLFLTMEITPKLPVNLLRAGRVLVFEPPPGIKANLLRTLSSINNQRMSKEPVERSRLYFLLAWLNAIVQERLRYVPLGYSKKYEFGESDFKCALDTIDTWVDGAAMGRTNLPPEKIPWVALQTLLGSCIYGGKIDNAFDQRLLNSFLGYLFTEKCFDHNFALVSDADD--GSNIAFPESTKHTDILQWVHKLPDLQTPSWLGLPNSAEKVLLTNLGQSLIGNILKMQQSLEDDEELVVGQSKTKRTIEVGDGRPAWMRQLYQSTQTWLQILPKSVTPLQRTIENIKDPMYRCFEREVNSGCNLLASVRKDLEDVAEVCKGAKKPTNHHRSMMADLAKGIIPKMWIRYAIPPGLTVIQWIQDFADRIKQLLHISDTAAKSGVIALRSIQVWLGGLFMAEAYITATRQSVAQNNKWALEELFLDVEL------GEGKVDSNTCVIT--GLRLMGSEIVDPRTLKLSTLIYKDIDICRLKWIRVEKSQQLEGSSAK-DKVCLPIYLNAARSTVLFTLYFSTTDSSYDFYKRGVAI 14048 MAD + P Q ++ P + A C+L DD+ + L +P + + KFI+D Q+ +L +Q+ K ++E+G+E + + +V F S+K Q+ +FIK V+EADK+ S QL+ L++ DG P+ET+HS++ + P++KSYI++ G+ M PSVEK + ELE+GLLHLQQNI+IPEITL+ HP VA ++++K A+ SDFEDK ED FLN LQ+GVNRWIKEIQKVTKL RDP++GTALQEI+FWLNLE SL +IQEKRESLEV LTL ILK AKRFHA SF+ DT L A V DYN LMKDFP+NDLL+A++LD+I A+Q IF+HL+K+R TKYPV R ++L++A+S DL++QL+KV+ LM MP++EFE++ AC +VF+TW+DE D++Q LLRDI KKKREE + W+ H++LQ RL++++KFR+QHEQLRQVI+RVL+P V +AG KD++ DK + L +++D ++I+EVN AYEIVK IDCLD KE D W+AA+KRY+ERIDRVE+RIA+ LRDLLG +KNANEMFRYFSRFNALFVRPHIRGAI EYQTQLIQRVKDDIEALH KFK QY+SS A M+K RDLPPV+GSIIW RQI RQLNAY+ RVEDVLGK W H +GQ LK +GESFK KLNT+E+FE W +KV++K + V+G IFN+E R + ++ E Q +TVLKL+VNF P+V TLAKEVRNM+ LGFR PL IVN+AH NQLYPFA+SLIESVRTYESTC KIEEH+ QNI LL AGLR+D QL I EG+ + WESYRL YVQK +E + FQEKVDDL+ +EID VK+LETC Y+K FEEI+ +IQ+AVD ++LHQ+SNL QWVS LD VE+RL+VRLEAG+ EW + L+GE E E DD D + +K+ LGG+P++K ++HELRITNQQMHL+PSIEVA Q++L + SW+ I+LNL RI HSRYQVGLE SD K YKK+L +L + E+LE A+ A+ +++ +A EYVKTWT+YQ+LWDLQ DQ++ I D VWMNVL+EIKSMR+HFDVAE+QKEFGP+VI FGKVQSKVS+KYDNWHK++L+KFG ++G M LYNEV +AR ++EQQ++++G T+E+VN ITY Q +KRKM WEKQ E R GQNIL RDRFQFP+ WLDSENI GEWSAF+EI+RRK+ ISSQVASLQMK+ EDK+VE+KTTE+L NWEK+KP+ GD+ PEEAV+++ ILEGKF RL+EEREN+Q+AKEALELTE GV SE++V A+ EL DLKNVW EL +WE+I +KETPW +VQPRKLRQ ++ + Q+KELP +QYAS+EHV+ L+ Y KVN +VELKSEA+KERHW+MLM+KLNV W+++EL LG VWDIDL KN+ IIRE+L IAQGEKALEE+L+Q+TE WKNY L+L +YQ+K ++I+GWDDLF +VKE IN++T+MK SPYFKQFEEEA AWEDRLN+INALFDVWIDVQRRW+YLDGIFAGSADIK+LLP ESQRFQSVSTEFLGLMKKV KSPLV DVLNI+ V RQLERLADLL KIQ+SLGEYLERQRSSFPRFYFVGDEDLLEIIGNSK++ +LQKHFKKMFAGVHSI L+ED +LG+ SKEGEE+ FI PVSI ++P INDWLT +E+EMRVSLA YL A++++ R +++K F+ WLD++ AQ+VVLAAQ+ WSE+V+A+LA+ L + V + L +LAD+VLYEQPPVRRRKLEHLIIE+VHQRDV+R L + +S+++FDW+SQMRFYFDPKQTDPLHQ+SI +AN KF YGFEYLGV DRLVQTPLTDRCYLT+TQALE RLGGSPFGPAGTGKTESVK+LG QLGRFVLVFNCDETFDF AMGRIFVGLCQVGAWGCFDEFNRLEERMLSAVSQQIQ IQE LR++ + KD + VELLGKQV V+PDMAIFITMNP YAGRSNLPDNLKKLFRSLAMTQPDRQLIAQVMLYSQGFRTAEVLA K+VPFF+LCDEQLS QSHYDFGLRALKSVLVS+GNVKR+RI++ K+ I+ARGE +NE++IAEQLPEQEILIQSVMETMVPKL+A+DIPLLYSLLTDVFPGV Y + M+ LR ELR+V +LVY++ E N TAG LWV+KVLQLYQIT IHHGLMMVGPSGSGK+MA R LL+ALE ++G+EGVAH+IDPKSI+K+SLYGY+DPNTREWTDGLFTHILR+IIDS+RGES KRQWI+FDGDVDPEWVENLNSVLDDN+LLTLPNGERL IPPNVRIMFEVQDL+YATLATVSRCGMVWFSE+V+ + + HF+ +L+ V + EGEE+ F + Q GA +S SP ++LQ V+S+L P F + GL+++CL Y+ L+HIMDF LRALTSLFS++KQ IRN++ YN HSDFP++ +QIE+YV+KSLI +++WSM GD +L RE+L Y++ I+T+ LP G IID+EV + G W AWS KVP IEVETHKIT+ DVVVPTMDTVRHEALLY WLAEHRP++LCGPPGSGKTMTLFSALR LPDMEVVGLNFSSATTPELM+KTFDQYCE RKTPNG+VLAP QLNKWL+FFCDEINLP+ DKYGTQRVISFLRQMVEH GFYR +DMQWV FERIQFVGACNPPTDPGRKPLSHRFLRHVPVVYVDYPGE SLKQIY TFNRAMLR+LPSLR AD LTNAMV+FFL +Q+RFT DMQPHYIYSPRE++RWVRGIHEALKPL+SLSVEGLVRIWAHEALRLFQDRL+EE ER WTD +I+++ALK+FP+I+KE AL RPIL+SNWLSK+Y +V QE LRDYVKARLKVFYEEELDVPLVLFNQVLDHVLRIDRVFRQPQGHLLLIG+SGAGKTTLSRFVSWINGLSVFQVKVHNKYTAEDFD+DLRNVLRR+GCKGEKITFIMDESNV+DSSFLER+NTLLANGEVPGLFEGDE LMTQCKEGA R+GLM+DS EELYKWFT QIC NLHVVFTMNPS DGLKD+ASTSPALFNRCVLNWFGDWS+EAYFQVG+EFT++ D+ER DYKVPD +P +AE LLP+ P +R++V NA VFVH T+H+AN R+QKR GR+ +TPRH+LD IAH++KL EKR+DLEEQQLHL GL+KI +TV+QVEVMQ+SLT+KRQELE MNEAANAKLKQMV DQQEAE++KT Q L+EELA QE F+NEK+ V EL QVEP VN+AKQAV IRK+DIQE+KAMKNPP AVK+A+ESIC LLGE +TDW+ IL I+KDTFV SILNFNTDD++D+ RETMKKKYL+NPDYNF+KVN+AS+ACGPMVKW +AQ+ YADILK VEPLRNEL L AA +N+++++ E I LE+SIAKY EEYA LISQAQ IKSDLA+VE+KV RSVAL+ SLSSER+RW+SG+ETFK+QM+TI GDCLLS+AFMAYGGYFDQH+R SLF TWC HL DI FRSDLA VEYLSNPD+RLRWQAN LP D+LCVENAI+L R+NRYPLIIDPSGQAT FLLNEYK KKI KTSFLDD+FRKTLESALRFGTPLLVQDVESYDPILNPVLNREVRRTGGRTLIT+GDQDIDLSPTF+IFLSTRDPSV+F PD+CSRVTFVNFTVTR SLQ QCLNAVLK ERPD+D KRSDLLK QGEFQL+LRHLEKDLLQSLNEA+GNLL++DKII RLETLK+EAA+VAKKVEETDV+M EVE+VS +YVPLAQSCS IYFTLEAMNQ+HFLYQYSLQ +LD+F+ VL N L +V+ + RLKIIT++LFQVTYNR+ARGMLH DQITFA +LARIFLKG ++ L+ EF FLR Q+ I ++ + + Q + ID +K KKL F ++ + + W +V PE+NVP LW ++ +Y+LL+IQA RPDRLLAS + +++ LG+ F + RG LDL SIVE E+ + +PILLCAVQG+DPSGRVED+ASE KQLT IAIGSAEGFSQA+KAINSAAK GKWVMLKNVHLA WLV LEKK+HS+Q HPNFRLFLTMEI PKLPVNLLRAGR VFEPPPGIK++LLRT +S+ R+SK P ERSRLYFLLAW NA+VQERLRYVPLG+SK+YEF ESD K A DTIDTWVD AAMGRTNLPPEK+PW AL+TLLG IYGGKIDN+FDQRL+ +FL LFTE F+H+F LV D D G +I PE + D+L W++KLPD+QTPSWLGLPN+AEKVLLTNLGQ + GN+LK+Q++ DDE L + K++ V D RP WMRQL S WL LPK+V L RT+EN++DP+YR FEREVNSG NLLASVR+DLE ++ VC G +KPTN +R MM+DL KG+IP W +Y +P +TVIQWI DF R+KQL+ IS+ AA GV ALR IQ+WLGGLFM EAYITATRQ VAQ+N WALEEL+LDV+L G+ S + T L LMG+E +D TL LS I D+ + LKWIR+ +Q E K V LP+Y+N ARS VLFTL S + S FY+RGVA+ Sbjct: 1 MADPGGDAPPVPAQPTATLADPSALSQYLFKAVSCILEDDDDGAVV-LRSVLEDPTGRDAIKKFISDPQIHSLIVQKLSNKDDDEDGAESGISYSVLTDVRFASSKVQSMVFIKRGAVLEADKSFSVQLRFLNFTDGSPYETLHSMISDAISPFYKSYIRESGRADRDGDK-MAPSVEKTMTELEMGLLHLQQNIDIPEITLSIHPVVAQVVKQKAEAGLRAKTSDFEDKMEDAHFLNALQSGVNRWIKEIQKVTKLERDPASGTALQEITFWLNLERSLFRIQEKRESLEVTLTLDILKHAKRFHALVSFEHDTGLQQALDTVNDYNPLMKDFPLNDLLAATELDEIRLAIQSIFTHLRKIRNTKYPVQRALRLVQAISNDLSSQLLKVLGTRRLMHMPFEEFERVMGACSKVFATWDDESDRLQGLLRDIIKKKREEQLRIGWRGAPAHRRLQIRLDHMRKFRHQHEQLRQVIMRVLRPAQTRVTHTDAG--KDELAGNQPGENASAETTKGPDKVSRKVQPLLDASDANAIEEVNLAYEIVKEIDCLDVTKEGTDAWEAAVKRYDERIDRVETRIAARLRDLLGTAKNANEMFRYFSRFNALFVRPHIRGAIREYQTQLIQRVKDDIEALHTKFKAQYSSSEAYHMTKCRDLPPVAGSIIWARQIERQLNAYLHRVEDVLGKGWEHHRDGQLLKTEGESFKAKLNTTEVFEAWVRKVSQKQVLVSGRIFNIEPIRARIATKEGETQTVTVLKLRVNFQPEVNTLAKEVRNMKWLGFRVPLGIVNQAHQTNQLYPFAVSLIESVRTYESTCIKIEEHQRQNIGLLCAGLRRDAQLFILEGMNLIWESYRLGVYVQKFSENMLQFQEKVDDLLQTTREIDLQVKSLETCVYSKAVFEEIIGKIQKAVDELNLHQYSNLPQWVSRLDEEVERRLVVRLEAGVREWTRALRGEKSEVENDDDAQDTHSSQQSKNPLGGEPKLKMIVHELRITNQQMHLHPSIEVAQQELLLSLGSWEGIVLNLPRIQHSRYQVGLEVGSDAHKNYKKILHNLDRADEALEQAHQAILDVVSEAREYVKTWTSYQALWDLQSDQVYGRIGTDTRVWMNVLDEIKSMRQHFDVAESQKEFGPIVIMFGKVQSKVSLKYDNWHKDILSKFGNHLGTEMQELYNEVSKARLDMEQQTVEAGSTSEAVNAITYAQTVKRKMKAWEKQVELYRTGQNILYRDRFQFPSGWLDSENILGEWSAFQEILRRKETAISSQVASLQMKVVAEDKVVENKTTELLLNWEKEKPVEGDIKPEEAVSLLTILEGKFTRLREERENIQRAKEALELTEFGVSSPSEQRVQVAIEELQDLKNVWLELSRVWEQIETLKETPWQTVQPRKLRQQLDTMANQIKELPTRLRQYASYEHVKRTLQSYAKVNVLVVELKSEALKERHWKMLMKKLNVDWTMSELTLGHVWDIDLQKNDSIIREILLIAQGEKALEEFLKQVTEEWKNYTLDLISYQNKCRLIRGWDDLFTRVKERINSLTAMKMSPYFKQFEEEALAWEDRLNRINALFDVWIDVQRRWVYLDGIFAGSADIKILLPQESQRFQSVSTEFLGLMKKVAKSPLVMDVLNISKVDRQLERLADLLSKIQRSLGEYLERQRSSFPRFYFVGDEDLLEIIGNSKNVPRLQKHFKKMFAGVHSIKLNEDSTEVLGLCSKEGEEVIFIKPVSIKDNPVINDWLTLLEREMRVSLATYLGKAIQDLQLLGVLYGPNSEKLRASGDLEKTGFLDWLDRFHAQLVVLAAQVIWSESVDAALAAMDGKPSKGPESPLHKCLASVENMLTVLADSVLYEQPPVRRRKLEHLIIEHVHQRDVIRTLIQNNANSSRSFDWLSQMRFYFDPKQTDPLHQVSIQMANTKFQYGFEYLGVIDRLVQTPLTDRCYLTLTQALEGRLGGSPFGPAGTGKTESVKALGTQLGRFVLVFNCDETFDFHAMGRIFVGLCQVGAWGCFDEFNRLEERMLSAVSQQIQSIQETLRDMACGAKTAGKDGVTVELLGKQVTVHPDMAIFITMNPDYAGRSNLPDNLKKLFRSLAMTQPDRQLIAQVMLYSQGFRTAEVLASKIVPFFQLCDEQLSAQSHYDFGLRALKSVLVSSGNVKRERIRRIKDDILARGETVNESSIAEQLPEQEILIQSVMETMVPKLVAEDIPLLYSLLTDVFPGVVYSPSAMEGLRRELRRVCNETYLVYNESGLFNEAAGHESNSNISGTTAGSLWVQKVLQLYQITCIHHGLMMVGPSGSGKSMAWRTLLKALERLEGVEGVAHVIDPKSINKESLYGYLDPNTREWTDGLFTHILRKIIDSIRGESLKRQWIIFDGDVDPEWVENLNSVLDDNRLLTLPNGERLGIPPNVRIMFEVQDLRYATLATVSRCGMVWFSEDVIPPELAMEHFIRQLQNVPIDEGEEETVGFGLPVVTPESSDQVQSPDFQDVPGASRESG-PVSPTLRLQCDVASVLQPHFADGGLVSRCLAYAKDLDHIMDFMPLRALTSLFSIMKQCIRNIMAYNMMHSDFPMSVDQIESYVSKSLIYAIIWSMCGDGRLSTREELGNYLREITTIPLPPTGA--PIIDYEVKLNGEWQAWSQKVPVIEVETHKITSMDVVVPTMDTVRHEALLYLWLAEHRPMILCGPPGSGKTMTLFSALRSLPDMEVVGLNFSSATTPELMMKTFDQYCECRKTPNGLVLAPVQLNKWLVFFCDEINLPNEDKYGTQRVISFLRQMVEHGGFYRTSDMQWVKFERIQFVGACNPPTDPGRKPLSHRFLRHVPVVYVDYPGELSLKQIYGTFNRAMLRLLPSLRSQADALTNAMVDFFLLSQKRFTQDMQPHYIYSPRELSRWVRGIHEALKPLDSLSVEGLVRIWAHEALRLFQDRLIEETERQWTDAHIDDIALKYFPSIDKEAALSRPILFSNWLSKEYCSVEQETLRDYVKARLKVFYEEELDVPLVLFNQVLDHVLRIDRVFRQPQGHLLLIGISGAGKTTLSRFVSWINGLSVFQVKVHNKYTAEDFDDDLRNVLRRAGCKGEKITFIMDESNVLDSSFLERINTLLANGEVPGLFEGDEFAALMTQCKEGATRDGLMVDSHEELYKWFTNQICTNLHVVFTMNPSEDGLKDRASTSPALFNRCVLNWFGDWSIEAYFQVGREFTSKTDMERPDYKVPDFVPAVAEHLLPECPSFREMVANAFVFVHTTLHRANARLQKRTGRSMWVTPRHFLDFIAHFVKLMTEKRSDLEEQQLHLQIGLQKINETVEQVEVMQKSLTQKRQELEQMNEAANAKLKQMVHDQQEAEKRKTMSQRLQEELASQEVFINEKRTLVMNELSQVEPAVNDAKQAVSEIRKRDIQELKAMKNPPAAVKLAIESICFLLGEYSTDWRQILTTIMKDTFVPSILNFNTDDITDSIRETMKKKYLNNPDYNFDKVNRASSACGPMVKWAIAQVQYADILKNVEPLRNELKALEQAASKNKEEAKNVESTIESLERSIAKYKEEYAVLISQAQAIKSDLATVEAKVERSVALIKSLSSERSRWESGAETFKSQMSTIFGDCLLSAAFMAYGGYFDQHLRASLFATWCQHLQSVDIRFRSDLALVEYLSNPDERLRWQANDLPNDELCVENAIMLTRFNRYPLIIDPSGQATEFLLNEYKAKKIMKTSFLDDAFRKTLESALRFGTPLLVQDVESYDPILNPVLNREVRRTGGRTLITIGDQDIDLSPTFSIFLSTRDPSVDFPPDVCSRVTFVNFTVTRGSLQTQCLNAVLKAERPDVDSKRSDLLKMQGEFQLRLRHLEKDLLQSLNEAEGNLLDDDKIITRLETLKQEAAEVAKKVEETDVIMSEVETVSQQYVPLAQSCSAIYFTLEAMNQVHFLYQYSLQFLLDVFTCVLTQNARLKDVRESVQRLKIITQDLFQVTYNRVARGMLHNDQITFAVLLARIFLKGQANSKSLSLDTEFDCFLRGQD--ILPKETTSKGSASADAEQTRMIDVLK--KKLASFRNLDSAIAQNRAAFSAWINSVAPEANVPVLWEPTKTEGPTPSWFTQAQTSLYHLLLIQAFRPDRLLASAHRLVSAALGEAFMDEARGHLDLLSIVEQEIRSNMPILLCAVQGFDPSGRVEDMASEHHKQLTNIAIGSAEGFSQADKAINSAAKNGKWVMLKNVHLAPGWLVQLEKKLHSVQPHPNFRLFLTMEINPKLPVNLLRAGRAFVFEPPPGIKSSLLRTFASVPAARISKAPAERSRLYFLLAWFNAVVQERLRYVPLGWSKRYEFNESDLKVACDTIDTWVDSAAMGRTNLPPEKVPWAALRTLLGQSIYGGKIDNSFDQRLMETFLSVLFTEASFEHDFPLVRDVDGNAGKHILVPEGSSRDDLLAWINKLPDVQTPSWLGLPNNAEKVLLTNLGQVMTGNLLKLQEAAADDESLPISAFDRKKSSVVSDARPPWMRQLLGSASAWLSSLPKTVKRLTRTVENLRDPLYRFFEREVNSGSNLLASVRQDLEVISAVCAGERKPTNRYRLMMSDLVKGLIPSDWRQYNVPKTMTVIQWISDFGLRVKQLVAISEAAATGGVTALRDIQIWLGGLFMPEAYITATRQFVAQSNGWALEELYLDVQLVLQGKGGKATASSTSGAFTVRDLTLMGAEPLDESTLHLSDTISVDLPLTVLKWIRLSADEQAERYVEKPGSVRLPVYMNGARSVVLFTLRLSAKEPSNRFYERGVAL 4736
BLAST of Cytoplasmic dynein 1 heavy chain 1 vs. TrEMBL
Match: A0A504YKS2 (Dynein heavy chain 1 cytosolic OS=Fasciola gigantica OX=46835 GN=FGIG_00108 PE=4 SV=1) HSP 1 Score: 6641.6 bits (17230), Expect = 0.000e+0 Identity = 3213/4732 (67.90%), Postives = 3846/4732 (81.28%), Query Frame = 3 Query: 126 QEITAISLP-KFIKYLTLYAFPCMLNDDESKSRKDYELFLSEPQNEECLTKFINDNQVTTLTIQQ--TKRXXXXXXXXXXXXKISNEVNFESNKSQTSIFIKNNQVIEADKTISSQLQVLSYCDGPPFETMHSLVCYGLLPYFXXXXXXXXXXXXXXXXXMVPSVEKKIAELEIGLLHLQQNIEIPEITLTPHPYVAHIIQEKLLQNKEARVSDFEDKFEDTQFLNQLQAGVNRWIKEIQKVTKLNRDPSTGTALQEISFWLNLEHSLDKIQEKRESLEVALTLAILKQAKRFHATTSFDTDTALSSAKIQVKDYNQLMKDFPINDLLSASQLDKISEALQQIFSHLKKVRATKYPVNRIIKLMEALSRDLTTQLMKVISNMHLMSMPYDEFEKIFTACQQVFSTWEDEYDKMQNLLRDIAKKKREEFTKFAWKMNATHKKLQTRLENIKKFRYQHEQLRQVIVRVLKPV-TKVVPSVEAG--VPKDQ-ITD--------KGDKSSTFLPESADTSSIDEVNAAYEIVKVIDCLDFAKEENDEWDAAIKRYEERIDRVESRIASHLRDLLGQSKNANEMFRYFSRFNALFVRPHIRGAIGEYQTQLIQRVKDDIEALHNKFKVQYASSTACKMSKVRDLPPVSGSIIWVRQILRQLNAYMKRVEDVLGKDWAQHIEGQKLKADGESFKLKLNTSELFEEWSKKVAEKSLSVAGSIFNVESTRTVVTVRDREPQKITVLKLKVNFLPDVITLAKEVRNMRALGFRTPLSIVNKAHSANQLYPFAISLIESVRTYESTCSKIEEHKMQNISLLTAGLRKDVQLCIHEGVQITWESYRLDQYVQKLAELVFSFQEKVDDLVIVIKEIDFNVKALETCSYNKQTFEEILIRIQEAVDNMSLHQFSNLAQWVSNLDSLVEQRLIVRLEAGLLEWIKVLKGXXXXXXXXXXXXXXXVNSMAKHRLGGKPQIKKLIHELRITNQQMHLYPSIEVATQDILYQMSSWQNIILNLSRIVHSRYQVGLETESDNQKTYKKLLSSLPNSGESLENAYAAVHNILRDANEYVKTWTNYQSLWDLQGDQLFSLIADDNTVWMNVLEEIKSMRKHFDVAETQKEFGPLVIAFGKVQSKVSMKYDNWHKEVLTKFGQNMGKMMTTLYNEVQRARNELEQQSIDSGGTNESVNFITYTQNIKRKMNTWEKQAEACRAGQNILCRDRFQFPNDWLDSENIQGEWSAFKEIMRRKQETISSQVASLQMKITEEDKIVESKTTEVLGNWEKDKPIAGDLTPEEAVNIIQILEGKFNRLKEERENVQKAKEALELTEIGVKPISEEKVTNALSELHDLKNVWNELKSIWEKIRDMKETPWLSVQPRKLRQDIENLTAQLKELPNSFKQYASFEHVRTLLKMYMKVNASIVELKSEAIKERHWRMLMRKLNVSWSLNELQLGKVWDIDLVKNEEIIREVLAIAQGEKALEEYLRQITEVWKNYVLELTNYQSKSKIIKGWDDLFNKVKEHINNVTSMKASPYFKQFEEEATAWEDRLNKINALFDVWIDVQRRWIYLDGIFAGSADIKVLLPVESQRFQSVSTEFLGLMKKVQKSPLVTDVLNIANVQRQLERLADLLGKIQKSLGEYLERQRSSFPRFYFVGDEDLLEIIGNSXXXXXXXXXXXXMFAGVHSIILSEDEKVILGMMSKEGEELRFISPVSIIEHPRINDWLTAMEKEMRVSLAKYLNVAVKEIS------GWRTE-----SNIDKDKFMVWLDKYQAQIVVLAAQITWSEAVEASLAS--------GVS-LESTMTVVHSTLNMLADTVLYEQPPVRRRKLEHLIIEYVHQRDVLRALHNDGVSSNKNFDWMSQMRFYFDPKQTDPLHQLSIHVANAKFHYGFEYLGVCDRLVQTPLTDRCYLTMTQALEARLGGSPFGPAGTGKTESVKSLGNQLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLSAVSQQIQGIQEALRELMVSK----KDSINVELLGKQVHVNPDMAIFITMNPGYAGRSNLPDNLKKLFRSLAMTQPDRQLIAQVMLYSQGFRTAEVLAGKVVPFFKLCDEQLSPQSHYDFGLRALKSVLVSAGNVKRDRIKQEKEKIVARGEEINETAIAEQLPEQEILIQSVMETMVPKLIADDIPLLYSLLTDVFPGVEYRQAEMKRLREELRKVSENKFLVYSDE---------------PNTAGYLWVEKVLQLYQITTIHHGLMMVGPSGSGKTMACRVLLQALENIDGIEGVAHIIDPKSISKDSLYGYMDPNTREWTDGLFTHILRRIIDSVRGESNKRQWIVFDGDVDPEWVENLNSVLDDNKLLTLPNGERLAIPPNVRIMFEVQDLKYATLATVSRCGMVWFSEEVLTTGMILTHFLNELKKVQV------------------MEGEEDFSVNQG--DTGADADSKISSSPIIQLQTQVSSILAPFFTEDGLIAKCLDYSTTLEHIMDFTRLRALTSLFSMIKQSIRNMIEYNQSHSDFPLNNEQIENYVAKSLISSVVWSMSGDSKLKVREQLSQYIKNISTVDLPTVGGIKNIIDFEVNIQGTWVAWSNKVPQIEVETHKITATDVVVPTMDTVRHEALLYTWLAEHRPVLLCGPPGSGKTMTLFSALRCLPDMEVVGLNFSSATTPELMLKTFDQYCEYRKTPNGIVLAPQQLNKWLIFFCDEINLPDMDKYGTQRVISFLRQMVEHHGFYRITDMQWVSFERIQFVGACNPPTDPGRKPLSHRFLRHVPVVYVDYPGETSLKQIYSTFNRAMLRMLPSLRGYADTLTNAMVEFFLKTQERFTHDMQPHYIYSPREMTRWVRGIHEALKPLESLSVEGLVRIWAHEALRLFQDRLVEEDERHWTDDNINEVALKHFPNINKEEALKRPILYSNWLSKDYSAVTQEELRDYVKARLKVFYEEELDVPLVLFNQVLDHVLRIDRVFRQPQGHLLLIGVSGAGKTTLSRFVSWINGLSVFQVKVHNKYTAEDFDEDLRNVLRRSGCKGEKITFIMDESNVMDSSFLERMNTLLANGEVPGLFEGDELTTLMTQCKEGAIREGLMIDSQEELYKWFTQQICRNLHVVFTMNPSADGLKDKASTSPALFNRCVLNWFGDWSLEAYFQVGKEFTNRLDLERTDYKVPDTLPCIAEGLLPQNPIYRDVVVNALVFVHQTMHQANVRVQKRGGRTAAITPRHYLDLIAHYMKLSAEKRADLEEQQLHLNNGLKKIEQTVDQVEVMQRSLTKKRQELENMNEAANAKLKQMVQDQQEAEQKKTTGQALKEELAKQEQFVNEKQKTVKQELDQVEPTVNEAKQAVQNIRKKDIQEIKAMKNPPNAVKMAVESICLLLGEKTTDWQSILKVIIKDTFVTSILNFNTDDVSDNTRETMKKKYLSNPDYNFEKVNKASNACGPMVKWVLAQISYADILKRVEPLRNELTELSDAAEQNRKKSQETEDLIAQLEKSIAKYTEEYATLISQAQTIKSDLASVESKVGRSVALLGSLSSERTRWDSGSETFKAQMATINGDCLLSSAFMAYGGYFDQHMRTSLFNTWCHHLSEADILFRSDLARVEYLSNPDDRLRWQANSLPADDLCVENAIILRRYNRYPLIIDPSGQATTFLLNEYKEKKITKTSFLDDSFRKTLESALRFGTPLLVQDVESYDPILNPVLNREVRRTGGRTLITLGDQDIDLSPTFTIFLSTRDPSVEFAPDICSRVTFVNFTVTRSSLQNQCLNAVLKIERPDIDQKRSDLLKAQGEFQLKLRHLEKDLLQSLNEAQGNLLENDKIIARLETLKREAADVAKKVEETDVVMQEVESVSTEYVPLAQSCSNIYFTLEAMNQIHFLYQYSLQLMLDIFSSVLINNPELTNVKAASDRLKIITKNLFQVTYNRLARGMLHEDQITFATILARIFLKG--STPIGFLENEFQHFLRSQEATITSSDSNKQDNLGLTLHQDQIDSVKRLK-KLKVFAKIEEKV-KSTKDIKNWTLTVTPESNVPELWVDDNNYNDEK--LSKIAKGMYNLLIIQAIRPDRLLASTQKFIASVLGDTFTESVRGTLDLASIVEVEVTACVPILLCAVQGYDPSGRVEDLASEQGKQLTGIAIGSAEGFSQAEKAINSAAKTGKWVMLKNVHLATSWLVSLEKKIHSLQAHPNFRLFLTMEITPKLPVNLLRAGRVLVFEPPPGIKANLLRTLSSINNQRMSKEPVERSRLYFLLAWLNAIVQERLRYVPLGYSKKYEFGESDFKCALDTIDTWVDGAAMGRTNLPPEKIPWVALQTLLGSCIYGGKIDNAFDQRLLNSFLGYLFTEKCFDHNFALVSDADD--GSNIAFPESTKHTDILQWVHKLPDLQTPSWLGLPNSAEKVLLTNLGQSLIGNILKMQQSLEDDEELV-VGQSKTKRTIEVGDGRPAWMRQLYQSTQTWLQILPKSVTPLQRTIENIKDPMYRCFEREVNSGCNLLASVRKDLEDVAEVCKGAKKPTNHHRSMMADLAKGIIPKMWIRYAIPPGLTVIQWIQDFADRIKQLLHISDTAAKSGVIALRSIQVWLGGLFMAEAYITATRQSVAQNNKWALEELFLDVEL----GEGKVDS---NTCVITGLRLMGSEIVDPRTLKLSTLIYKDIDICRLKWIRVEKSQQLEGSSAKDKVC-LPIYLNAARSTVLFTLYFSTTDSSYDFYKRGVAI 14048 Q + + + P KF YL L C L ++ S+ + L +P E + K+I D Q+ +L +Q+ K EEEEG + + I +V F S K Q+ +FIK +EADK S+QL+ L++ DG P+ET+HS++ + P++KSYI++ G+ M PSVEK + ELE+GLLHLQQNI+IPEITL+ HP VA +I+++ + K+A+ +DFEDK ED FLN LQAGVNRWIKEIQKVTKL+RDP++GTALQEI+FWLNLE SL +IQEKRESLEV LTL ILK AKRFHA SF+TD L A V DYN LMKDFP+NDLLSA++LDKI A+Q IF+HL+K+R TKYP+ R ++L+EA+SRDL+ Q++KV+ LM MP++EFE++ +C +VF+TW+DEY+++Q L+RDI KKKREE + W+ N H+ LQ RL+ ++KFR+QHEQLRQVIVRVL+P+ +V P + P DQ + D K D+ L +++D ++I+EVN AYEIVK +DCLD +KE D W+AAIKRY+ERIDRVE+RI S LRDLLG +KNANEMFRYFSRFNALFVRPHIRGAI EYQTQLIQRVKDDIEALH KFK+QY SS A M+K+RD+PPV+GSIIW RQI RQLNAY++RVEDVLGK W H +GQ LKADGESFK KLNT++LF+EW++KV +K + + G IFN+E TR V ++ E Q +TVLKLKVNF +VITLAKEVRNM+ LGFR PL+IVN+AH NQLYPFAISLIESVRTYESTC+KIEE++ QNI LL AGLR+D QL I EG+ + WESYRL +VQ+ AE V FQEKVDDL+ +EID VK+LETC Y+K FE I+ +IQ+AVD ++LHQ+SNL QWV+ LD VE+RL++RLEAG+ EW + L+GE + E +D D + + K+ LGG+PQ+K +HELRITNQQMHL+PSIEVA Q+++ + +W++ +L+L RI HSRYQVGLETESD Q+ YKKLL L N+GE LE A+ A+ +++ +A EYVKTWT+YQ+LWDLQGDQ++ I D VWMN+L+EIKSMR+HFDVAETQKEFGP+VI FGKVQSKVS+KYDNWHK+VL+KFG ++G+ M LY++V RAR +LEQQ+I++G T+++VN ITYTQ +KRKM WEKQ + R+GQNIL RDRFQFP+ WLDSENIQGEWSAF+EI+RRK+ +I SQVASLQ+K+ EDK+VESKT+E+L +WEK+KPIAG+L PEEAVN + ILEGKFNRL+EER+N+Q+AKEALELTE GV +E++V A EL DLKNVW EL +W++I +KETPW +VQPRKLRQ ++ + +Q+KELP+ +QYAS+EHV+ L+ Y K N IVELKSEA+KERHW+ LM+KLNV+W+++EL LG VWDIDL K + I+EVL +AQGEKALEE+L+Q+TE WKNY L+L YQ+K ++I+GWDDLF +VKE IN++T+MK SPYFKQFEEEA AWEDRLN+INALFDVWIDVQRRW+YLDGIFAGSADIKVLLP ESQRFQSVSTEFLGLMKKV KSPLV DVLNI+ V RQLERLADLL KIQ+SLGEYLERQRSSFPRFYFVGDEDLLEIIGNSK++ +LQKHFKKMFAGVH+I L+ED +LG+ SKEGEE+ F+ VSI ++P INDWLT +E+EMRVSLA YL A++E+ G TE ++ K F+ W+DK+QAQ+VVLAAQ+ WSEAV+A+L + G S L + + V L +LAD+VLYEQPPVRR+KLEHLIIE+VHQRDV+R L + VSS ++FDW+SQMRFYFDPKQ DPL Q+SI +AN KF YGFEYLGV DRLVQTPLTDRCYLT+TQALE RLGGSPFGPAGTGKTESVK+LG QLGRFVLVFNCDETFDF AMGRIFVGLCQVGAWGCFDEFNRLEERMLSAVSQQIQ IQE L+++ + KD+I VELLGKQV V+PDMAIFITMNP YAGRSNLPDNLKKLFRSLAMTQPDRQLIAQVMLYSQGFRTAE+LAGK+VPFF+LCDEQLS QSHYDFGLRALKSVLVS+GNVKRDRI++ KE +V+RGE INETAIAEQLPEQEILIQSVMETMVPKL+A+DIPLLYSLLTDVFPGV Y Q+ M+ LR ELR+V + +LVY++ T G LWV+KVLQLYQIT IHHGLMMVGPSGSGK+ A RVLL+ALE ++G+EGVAH+IDPKSISK+SLYGY+DPNTREWTDGLFTHILR+IIDS+RGES KRQWI+FDGDVDPEWVENLNSVLDDN+LLTLPNGERL IPPNVRIMFEVQDL+YATLATVSRCGMVWFSE+V+T +++ HF+ +L+ V V G D + + G +TG + S +QLQ V+SIL P F + GL+++CL Y+ L+HIMDF LR+LTSLFSM+KQ+IRN++ YN +H DFP+ ++QIE+YV+KSL+ +++WSM GD +L REQ+ Y++ I+T+ LP G IIDFEV + G W W+ KVP IEVETHKIT+ DVVVPTMDTVRHEALLY WLAEHRP++LCGPPGSGKTMTLFSALR LPDMEVVGLNFSSATTPELM+KTFDQYCE RKTPNG+VLAP QLNKWL+FFCDEINLP+ DKYGTQRVISFLRQMVEH GFYR +DMQWV FERIQFVGACNPPTDPGRKPLSHRFLRHVPVVYVDYPGE SLKQIY TFNRAMLR+LPSLR +AD LTNAMVEFFL +Q+RFT DMQPHYIYSPRE++RWVRGIHEALKPL+SLSVEGLVR+WAHEALRLFQDRL+E+ ER WTD +I+EVALK+FP+I+ AL+RPIL+SNWLSK+Y +V QE LRDYVKARLKVFYEEELDVPLVLFNQVLDHVLRIDRVFRQPQGHLLLIG+SGAGKTTLSRFVSWINGLSVFQVKVHNKYTAEDFD+DLRNVLRR+GCKGEKITFIMDESNV+DS FLER+NTLLANGEVPGLFEGDE LMTQCKEGA REGLM+DS EELYKWFT QIC NLHVVFTMNPS DGLKD+ASTSPALFNRCVLNWFGDWS+EAY+QVGKEFT++ D+ER+DYKVPD +P +A+ LLP+ P +RD+V NA VFVHQT+H+ANVR++KRGGRT ITPRHYLD IAH+++L AEKR+DLEEQQLHL GL+KI++TV+QVEVMQ+SLT+KRQEL+ MNEAANAKLKQMVQDQQEAE++KT Q L+EELA QE F+NEK+ V EL QVEP VNEAKQAV IRK+DIQEIKAMKNPP +KMAVESICLLLG+ +TDW+ IL ++KDTFV SILNFNTDD++D+ RETMKKKYLSNPDYNFEKV++AS ACGPMVKW +AQISYADILK+VEPLRNEL +L +AA +N+++++ E I LE+SIAKY EEYA LISQAQ IK+DLA+VE+KV RSVAL+ SLSSER RWDSG+ETFK+QMATI GDCLLS+AFMAYGGY+DQH+R SL TWC HL DI FRSDLA VEYLSNPD+RLRWQAN LP D+LCVENAI+LRR+NRYPLIIDPSGQAT F+LNEYK KKI KTSFLDD+FRKTLESALRFGTPLLVQDVESYDPILNPVLNREVRRTGGRTLITLGDQDIDLSPTF +FLSTRDPSVEF D+CSRVTFVNFTVTR SLQ QCLNAVLK ERPD+D KRSDLLK QGEFQL+LRHLEKDLLQSLNEA+GNLL++DKII RLETLK+EA +VAKKVEETDV+M EVE+VS +YV LA SCSNIYFTLE+MNQ+HFLY YSLQ +LD+FS VL NP L +V+ + RLK+ITK+LFQ+TYNR+ARGMLH DQITFA +LARIF+KG S LE+EF FLRSQ+A + S + + +++Q V RLK + + F K++ + + + +W +V PE+ +P LW +++ + MYNLL+IQA RPDRLLAS + + S+ G+TF E RG LDL IVE E+ +P+LLCAVQG+DPSGRVED+ASE KQLT IAIGSAEGFSQA+KAINSAAK GKWV+LKNVHLA WLV LEKK+H++Q HPNFRLFLTMEI PKLPVNLLRAGRV VFEPPPGIK++LLRT ++I N R+S+ P ERSRLYFLLAW NA+VQERLRYVPLG+SK+YEF ESD K A DTIDTWVD AA+GRTNLPPEK+PW AL+TLLG IYGGKIDN+FDQRL+ +FL LFTE F+H+F LV D D G NI PE + ++L W+HKLPD+QTPSWLGLPN+AEKVLLTNLG + GN+LK+Q+++ DD+ LV G K++ V D RPAWM+QL + +WL +LPK + L RT++N++DP+YR FEREVNSG NLL +VR+DLE V +C G +KPTN HR +M+DL KGIIP W RY +P +TVIQWI DFA RIKQL+ +S A GV AL+ IQVWLGGLFM EAYITATRQ VAQ+N WALEEL+LDV L G K+ S ++ L+LMG+E VD T++L I D+ LKWIR+ +Q + ++ V LP+Y+N +R+TVLFTL +T ++ FY+RGVA+ Sbjct: 13 QPVVSFADPAKFSDYL-LKTVSCFL-EESSEGVAAIKKALDDPAARETIKKYITDPQLHSLIVQKLSNKDEEEEGGDVSISYSILIDVKFTSPKVQSVVFIKRGPAVEADKNFSTQLRFLNFTDGSPYETLHSMISDAISPFYKSYIRESGRADRDGDK-MAPSVEKTMTELEMGLLHLQQNIDIPEITLSVHPVVAQMIRQRAEEGKKAKATDFEDKLEDAHFLNSLQAGVNRWIKEIQKVTKLDRDPASGTALQEITFWLNLERSLARIQEKRESLEVTLTLDILKHAKRFHALVSFETDPGLQQALATVNDYNPLMKDFPLNDLLSATELDKIRLAVQSIFTHLRKIRNTKYPLQRALRLIEAISRDLSAQILKVLGTRRLMHMPFEEFERVMASCFEVFATWDDEYERLQGLMRDIIKKKREEQMRMVWRSNPAHRHLQIRLDQMRKFRHQHEQLRQVIVRVLRPLPARVAPGDKESNDHPTDQPVADAAVLGGSAKSDEKEQPLLDASDANAIEEVNLAYEIVKEVDCLDVSKEGTDIWEAAIKRYDERIDRVETRITSRLRDLLGTAKNANEMFRYFSRFNALFVRPHIRGAIREYQTQLIQRVKDDIEALHAKFKIQYLSSNAYHMTKLRDVPPVAGSIIWARQIERQLNAYLRRVEDVLGKGWEHHRDGQLLKADGESFKAKLNTTDLFDEWTRKVQQKQILMFGRIFNIEPTRARVATKEGETQTVTVLKLKVNFQLEVITLAKEVRNMKWLGFRVPLAIVNRAHQTNQLYPFAISLIESVRTYESTCNKIEENQRQNIGLLCAGLRRDAQLLISEGMALVWESYRLGMFVQRFAENVLQFQEKVDDLLHKTREIDHEVKSLETCVYSKAVFEGIIAKIQKAVDELNLHQYSNLPQWVARLDEEVERRLVIRLEAGIHEWTRALRGERHDAEAEDADDTHE-SQQTKNPLGGEPQLKISLHELRITNQQMHLHPSIEVAQQELMLSLGAWESTVLSLPRIQHSRYQVGLETESDTQRNYKKLLHDLQNTGEVLEEAHQAIMDVVDEAREYVKTWTSYQALWDLQGDQVYGRIGTDTQVWMNLLDEIKSMRQHFDVAETQKEFGPIVIMFGKVQSKVSLKYDNWHKDVLSKFGSHLGQEMQDLYSQVSRARLDLEQQAIEAGSTSDAVNAITYTQTVKRKMKAWEKQVDLYRSGQNILYRDRFQFPSQWLDSENIQGEWSAFQEILRRKETSIGSQVASLQIKVVAEDKVVESKTSELLSSWEKEKPIAGNLKPEEAVNQLTILEGKFNRLREERKNIQRAKEALELTEFGVHSPTEQRVQVATEELQDLKNVWVELSQVWDQIEALKETPWQTVQPRKLRQQLDTMASQIKELPSRLRQYASYEHVKRTLQNYAKANVIIVELKSEALKERHWKTLMKKLNVNWTMSELTLGHVWDIDLQKQDAAIKEVLLVAQGEKALEEFLKQVTEEWKNYTLDLVGYQNKCRLIRGWDDLFTRVKERINSLTAMKLSPYFKQFEEEALAWEDRLNRINALFDVWIDVQRRWVYLDGIFAGSADIKVLLPQESQRFQSVSTEFLGLMKKVAKSPLVMDVLNISKVDRQLERLADLLSKIQRSLGEYLERQRSSFPRFYFVGDEDLLEIIGNSKNVPRLQKHFKKMFAGVHAIKLNEDSTEVLGLCSKEGEEVLFMKSVSIKDNPVINDWLTLLEREMRVSLATYLGRAIQELQQTGVLYGSNTEKLKSAGDLGKTGFIAWVDKFQAQLVVLAAQVIWSEAVDAALTAMDGKPATEGDSPLHNCLKSVEGMLTVLADSVLYEQPPVRRQKLEHLIIEHVHQRDVIRNLIQNNVSSPRSFDWLSQMRFYFDPKQQDPLRQVSIQMANTKFQYGFEYLGVIDRLVQTPLTDRCYLTLTQALEGRLGGSPFGPAGTGKTESVKALGTQLGRFVLVFNCDETFDFHAMGRIFVGLCQVGAWGCFDEFNRLEERMLSAVSQQIQSIQETLKDMAGASRPQGKDTITVELLGKQVTVHPDMAIFITMNPDYAGRSNLPDNLKKLFRSLAMTQPDRQLIAQVMLYSQGFRTAEILAGKIVPFFQLCDEQLSQQSHYDFGLRALKSVLVSSGNVKRDRIRKIKEDLVSRGETINETAIAEQLPEQEILIQSVMETMVPKLVAEDIPLLYSLLTDVFPGVVYSQSAMEGLRRELRRVCKEMYLVYNEAGLFDTGGGMDASSIGSTTGGTLWVQKVLQLYQITCIHHGLMMVGPSGSGKSSAWRVLLKALERLEGVEGVAHVIDPKSISKESLYGYLDPNTREWTDGLFTHILRKIIDSIRGESLKRQWIIFDGDVDPEWVENLNSVLDDNRLLTLPNGERLGIPPNVRIMFEVQDLRYATLATVSRCGMVWFSEDVVTPELVMEHFILQLQNVPVDEGEEESGGFGLGSALPETAGSPDGATSPGLPETGGLPQGNVPVSATLQLQCDVASILQPHFGDGGLVSRCLAYAKDLDHIMDFMPLRSLTSLFSMLKQTIRNILAYNMTHPDFPMPSDQIESYVSKSLVYAIIWSMCGDGRLSTREQMGDYLREITTIPLPPQGA--PIIDFEVTLLGDWKPWAQKVPIIEVETHKITSMDVVVPTMDTVRHEALLYLWLAEHRPMVLCGPPGSGKTMTLFSALRSLPDMEVVGLNFSSATTPELMMKTFDQYCECRKTPNGMVLAPVQLNKWLVFFCDEINLPNEDKYGTQRVISFLRQMVEHGGFYRTSDMQWVKFERIQFVGACNPPTDPGRKPLSHRFLRHVPVVYVDYPGELSLKQIYGTFNRAMLRLLPSLRPHADALTNAMVEFFLLSQKRFTQDMQPHYIYSPRELSRWVRGIHEALKPLDSLSVEGLVRMWAHEALRLFQDRLIEDMERQWTDAHIDEVALKYFPSIDTVAALQRPILFSNWLSKEYCSVEQEALRDYVKARLKVFYEEELDVPLVLFNQVLDHVLRIDRVFRQPQGHLLLIGISGAGKTTLSRFVSWINGLSVFQVKVHNKYTAEDFDDDLRNVLRRAGCKGEKITFIMDESNVLDSGFLERINTLLANGEVPGLFEGDEFAALMTQCKEGAAREGLMVDSNEELYKWFTNQICTNLHVVFTMNPSEDGLKDRASTSPALFNRCVLNWFGDWSVEAYYQVGKEFTDKTDMERSDYKVPDVIPAVADQLLPEFPTFRDMVSNAFVFVHQTLHRANVRLRKRGGRTMWITPRHYLDFIAHFVRLMAEKRSDLEEQQLHLQIGLQKIKETVEQVEVMQKSLTQKRQELKQMNEAANAKLKQMVQDQQEAEKRKTMSQRLQEELANQEVFINEKRALVMNELSQVEPAVNEAKQAVLEIRKRDIQEIKAMKNPPPVIKMAVESICLLLGDHSTDWRQILTTVMKDTFVPSILNFNTDDITDSIRETMKKKYLSNPDYNFEKVSRASTACGPMVKWAIAQISYADILKKVEPLRNELRQLEEAATKNKEEAKNVESTIESLERSIAKYKEEYAVLISQAQAIKADLATVEAKVERSVALIKSLSSERGRWDSGAETFKSQMATIFGDCLLSAAFMAYGGYYDQHLRASLMATWCQHLQTVDIRFRSDLALVEYLSNPDERLRWQANDLPTDELCVENAIMLRRFNRYPLIIDPSGQATEFILNEYKAKKIMKTSFLDDAFRKTLESALRFGTPLLVQDVESYDPILNPVLNREVRRTGGRTLITLGDQDIDLSPTFLVFLSTRDPSVEFPADVCSRVTFVNFTVTRGSLQTQCLNAVLKAERPDVDAKRSDLLKMQGEFQLRLRHLEKDLLQSLNEAEGNLLDDDKIITRLETLKQEAGEVAKKVEETDVIMSEVETVSQQYVALAHSCSNIYFTLESMNQVHFLYHYSLQFLLDVFSHVLSKNPHLKDVRDYAQRLKVITKDLFQITYNRVARGMLHNDQITFAVLLARIFIKGQVSAQSPGLESEFNCFLRSQDALSKDAQSTGETRDSDSDNKEQQRCVARLKAQFEHFKKLDSMIAQKQSEFDSWLSSVAPETCIPTLWESAKTESNQPGWFAAAQASMYNLLLIQAFRPDRLLASAHRLVTSIFGETFMEEARGHLDLLPIVEQELRPNMPVLLCAVQGFDPSGRVEDMASEHHKQLTNIAIGSAEGFSQADKAINSAAKNGKWVLLKNVHLAPGWLVQLEKKLHNVQPHPNFRLFLTMEINPKLPVNLLRAGRVFVFEPPPGIKSSLLRTFANIPNNRISRAPAERSRLYFLLAWFNAVVQERLRYVPLGWSKRYEFTESDLKVACDTIDTWVDSAALGRTNLPPEKVPWAALRTLLGQSIYGGKIDNSFDQRLMETFLSVLFTEASFEHDFPLVRDVDGQVGKNIVVPEGSSRDELLSWIHKLPDIQTPSWLGLPNNAEKVLLTNLGHEMTGNLLKLQEAVADDDSLVSTGVLDRKKSSVVVDSRPAWMKQLLSTASSWLSLLPKKLKRLTRTVDNLRDPLYRFFEREVNSGANLLNTVRQDLETVIAICSGERKPTNRHRLLMSDLVKGIIPNDWRRYTVPKVITVIQWINDFAMRIKQLITVSQAAGSGGVAALQDIQVWLGGLFMPEAYITATRQFVAQSNGWALEELYLDVRLVQSGGSKKIASPGGGAFIVHDLKLMGAEPVDDSTIRLCDKISVDLPCTILKWIRLSTDEQTKRYMERNGVVRLPVYMNGSRATVLFTLQLNTKETYTRFYERGVAL 4738
BLAST of Cytoplasmic dynein 1 heavy chain 1 vs. TrEMBL
Match: A0A4S2M0W7 (Uncharacterized protein OS=Opisthorchis felineus OX=147828 GN=CRM22_003509 PE=4 SV=1) HSP 1 Score: 6630.81 bits (17202), Expect = 0.000e+0 Identity = 3212/4763 (67.44%), Postives = 3822/4763 (80.24%), Query Frame = 3 Query: 87 MADITANLVQPPDQEITAISLPKFIKYLTLYAFPCMLNDDESKSRKDYELFLSEPQNEECLTKFINDNQVTTLTIQQ--TKRXXXXXXXXXXXXKISNEVNFESNKSQTSIFIKNNQVIEADKTISSQLQVLSYCDGPPFETMHSLVCYGLLPYFXXXXXXXXXXXXXXXXXMVPSVEKKIAELEIGLLHLQQNIEIPEITLTPHPYVAHIIQEKLLQNKEARVSDFEDKFEDTQFLNQLQAGVNRWIKEIQKVTKLNRDPSTGTALQEISFWLNLEHSLDKIQEKRESLEVALTLAILKQAKRFHATTSFDTDTALSSAKIQVKDYNQLMKDFPINDLLSASQLDKISEALQQIFSHLKKVRATKYPVNRIIKLMEALSRDLTTQLMKVISNMHLMSMPYDEFEKIFTACQQVFSTWEDEYDKMQNLLRDIAKKKREEFTKFAWKMNATHKKLQTRLENIKKFRYQHEQLRQVIVRVLKPVTKVVPSVEAGVPKDQIT----------------DKGDKSSTFLPESADTSSIDEVNAAYEIVKVIDCLDFAKEENDEWDAAIKRYEERIDRVESRIASHLRDLLGQSKNANEMFRYFSRFNALFVRPHIRGAIGEYQTQLIQRVKDDIEALHNKFKVQYASSTACKMSKVRDLPPVSGSIIWVRQILRQLNAYMKRVEDVLGKDWAQHIEGQKLKADGESFKLKLNTSELFEEWSKKVAEKSLSVAGSIFNVESTRTVVTVRDREPQKITVLKLKVNFLPDVITLAKEVRNMRALGFRTPLSIVNKAHSANQLYPFAISLIESVRTYESTCSKIEEHKMQNISLLTAGLRKDVQLCIHEGVQITWESYRLDQYVQKLAELVFSFQEKVDDLVIVIKEIDFNVKALETCSYNKQTFEEILIRIQEAVDNMSLHQFSNLAQWVSNLDSLVEQRLIVRLEAGLLEWIKVLKGXXXXXXXXXXXXXXXVNSMAKHRLGGKPQIKKLIHELRITNQQMHLYPSIEVATQDILYQMSSWQNIILNLSRIVHSRYQVGLETESDNQKTYKKLLSSLPNSGESLENAYAAVHNILRDANEYVKTWTNYQSLWDLQGDQLFSLIADDNTVWMNVLEEIKSMRKHFDVAETQKEFGPLVIAFGKVQSKVSMKYDNWHKEVLTKFGQNMGKMMTTLYNEVQRARNELEQQSIDSGGTNESVNFITYTQNIKRKMNTWEKQAEACRAGQNILCRDRFQFPNDWLDSENIQGEWSAFKEIMRRKQETISSQVASLQMKITEEDKIVESKTTEVLGNWEKDKPIAGDLTPEEAVNIIQILEGKFNRLKEERENVQKAKEALELTEIGVKPISEEKVTNALSELHDLKNVWNELKSIWEKIRDMKETPWLSVQPRKLRQDIENLTAQLKELPNSFKQYASFEHVRTLLKMYMKVNASIVELKSEAIKERHWRMLMRKLNVSWSLNELQLGKVWDIDLVKNEEIIREVLAIAQGEKALEEYLRQITEVWKNYVLELTNYQSKSKIIKGWDDLFNKVKEHINNVTSMKASPYFKQFEEEATAWEDRLNKINALFDVWIDVQRRWIYLDGIFAGSADIKVLLPVESQRFQSVSTEFLGLMKKVQKSPLVTDVLNIANVQRQLERLADLLGKIQKSLGEYLERQRSSFPRFYFVGDEDLLEIIGNSXXXXXXXXXXXXMFAGVHSIILSEDEKVILGMMSKEGEELRFISPVSIIEHPRINDWLTAMEKEMRVSLAKYLNVAVKEISGWRTESNIDKDKFMVWLDKYQAQIVVLAAQITWSEAVEASLA---------SGVSLESTMTVVHSTLNMLADTVLYEQPPVRRRKLEHLIIEYVHQRDVLRALHNDGVSSNKNFDWMSQMRFYFDPKQTDPLHQLSIHVANAKFHYGFEYLGVCDRLVQTPLTDRCYLTMTQALEARLGGSPFGPAGTGKTESVKSLGNQLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLSAVSQQIQGIQEALRELM----VSKKDSINVELLGKQVHVNPDMAIFITMNPGYAGRSNLPDNLKKLFRSLAMTQPDRQLIAQVMLYSQGFRTAEVLAGKVVPFFKLCDEQLSPQSHYDFGLRALKSVLVSAGNVKRDRIKQEKEKIVARGEEINETAIAEQLPEQEILIQSVMETMVPKLIADDIPLLYSLLTDVFPGVEYRQAEMKRLREELRKVSENKFLVYSD----------EPN------TAGYLWVEKVLQLYQITTIHHGLMMVGPSGSGKTMACRVLLQALENIDGIEGVAHIIDPKSISKDSLYGYMDPNTREWTDGLFTHILRRIIDSVRGESNKRQWIVFDGDVDPEWVENLNSVLDDNKLLTLPNGERLAIPPNVRIMFEVQDLKYATLATVSRCGMVWFSEEVLTTGMILTHFLNELKKVQVMEGEEDFSVNQG------------------DTGADADSKISSSPIIQLQTQVSSILAPFFTEDGLIAKCLDYSTTLEHIMDFTRLRALTSLFSMIKQSIRNMIEYNQSHSDFPLNNEQIENYVAKSLISSVVWSMSGDSKLKVREQLSQYIKNISTVDLPTVGGIKNIIDFEVNIQGTWVAWSNKVPQIEVETHKITATDVVVPTMDTVRHEALLYTWLAEHRPVLLCGPPGSGKTMTLFSALRCLPDMEVVGLNFSSATTPELMLKTFDQYCEYRKTPNGIVLAPQQLNKWLIFFCDEINLPDMDKYGTQRVISFLRQMVEHHGFYRITDMQWVSFERIQFVGACNPPTDPGRKPLSHRFLRHVPVVYVDYPGETSLKQIYSTFNRAMLRMLPSLRGYADTLTNAMVEFFLKTQERFTHDMQPHYIYSPREMTRWVRGIHEALKPLESLSVEGLVRIWAHEALRLFQDRLVEEDERHWTDDNINEVALKHFPNINKEEALKRPILYSNWLSKDYSAVTQEELRDYVKARLKVFYEEELDVPLVLFNQVLDHVLRIDRVFRQPQGHLLLIGVSGAGKTTLSRFVSWINGLSVFQVKVHNKYTAEDFDEDLRNVLRRSGCKGEKITFIMDESNVMDSSFLERMNTLLANGEVPGLFEGDELTTLMTQCKEGAIREGLMIDSQEELYKWFTQQICRNLHVVFTMNPSADGLKDKASTSPALFNRCVLNWFGDWSLEAYFQVGKEFTNRLDLERTDYKVPDTLPCIAEGLLPQNPIYRDVVVNALVFVHQTMHQANVRVQKRGGRTAAITPRHYLDLIAHYMKLSAEKRADLEEQQLHLNNGLKKIEQTVDQVEVMQRSLTKKRQELENMNEAANAKLKQMVQDQQEAEQKKTTGQALKEELAKQEQFVNEKQKTVKQELDQVEPTVNEAKQAVQNIRKKDIQEIKAMKNPPNAVKMAVESICLLLGEKTTDWQSILKVIIKDTFVTSILNFNTDDVSDNTRETMKKKYLSNPDYNFEKVNKASNACGPMVKWVLAQISYADILKRVEPLRNELTELSDAAEQNRKKSQETEDLIAQLEKSIAKYTEEYATLISQAQTIKSDLASVESKVGRSVALLGSLSSERTRWDSGSETFKAQMATINGDCLLSSAFMAYGGYFDQHMRTSLFNTWCHHLSEADILFRSDLARVEYLSNPDDRLRWQANSLPADDLCVENAIILRRYNRYPLIIDPSGQATTFLLNEYKEKKITKTSFLDDSFRKTLESALRFGTPLLVQDVESYDPILNPVLNREVRRTGGRTLITLGDQDIDLSPTFTIFLSTRDPSVEFAPDICSRVTFVNFTVTRSSLQNQCLNAVLKIERPDIDQKRSDLLKAQGEFQLKLRHLEKDLLQSLNEAQGNLLENDKIIARLETLKREAADVAKKVEETDVVMQEVESVSTEYVPLAQSCSNIYFTLEAMNQIHFLYQYSLQLMLDIFSSVLINNPELTNVKAASDRLKIITKNLFQVTYNRLARGMLHEDQITFATILARIFLKG--STPIGFLENEFQHFLRSQEATITSSDSNKQDNLGLTLHQDQ-IDSVKRLKKLKVFAKIEEKVKSTK-DIKNWTLTVTPESNVPELW--VDDNNYNDEKLSKIAKGMYNLLIIQAIRPDRLLASTQKFIASVLGDTFTESVRGTLDLASIVEVEVTACVPILLCAVQGYDPSGRVEDLASEQGKQLTGIAIGSAEGFSQAEKAINSAAKTGKWVMLKNVHLATSWLVSLEKKIHSLQAHPNFRLFLTMEITPKLPVNLLRAGRVLVFEPPPGIKANLLRTLSSINNQRMSKEPVERSRLYFLLAWLNAIVQERLRYVPLGYSKKYEFGESDFKCALDTIDTWVDGAAMGRTNLPPEKIPWVALQTLLGSCIYGGKIDNAFDQRLLNSFLGYLFTEKCFDHNFALVSDADD--GSNIAFPESTKHTDILQWVHKLPDLQTPSWLGLPNSAEKVLLTNL---------------------------GQSLIGNILKMQQSLEDDEELVVGQSKTKRTIEVGDGRPAWMRQLYQSTQTWLQILPKSVTPLQRTIENIKDPMYRCFEREVNSGCNLLASVRKDLEDVAEVCKGAKKPTNHHRSMMADLAKGIIPKMWIRYAIPPGLTVIQWIQDFADRIKQLLHISDTAAKSGVIALRSIQVWLGGLFMAEAYITATRQSVAQNNKWALEELFLDVEL---GE-----GKVDSNTCVITGLRLMGSEIVDPRTLKLSTLIYKDIDICRLKWIRVEKSQQLEGSSAK-DKVCLPIYLNAARSTVLFTLYFSTTDSSYDFYKRGVAI 14048 MAD + P Q ++ P + C+L +D+ + L +P + + KFI+D Q+ +L +Q+ K ++E+G+E + + +V F S+K Q+ +FIK V+EADK+ S QL+ L++ DG P+ET+HS++ + P++KSYI++ G+ M PSVEK + ELE+GLLHLQQNI+IPEITL+ HP VA ++++K A+ SDFEDK ED FLN LQ+GVNRWIKEIQKVTKL RDP++GTALQEI+FWLNLE SL +IQEKRESLEV LTL ILK AKRFHA SF+ DT L A V DYN LMKDFP+NDLL+A++LD+I A+Q IF+HL+K+R TKYPV R ++L++A+S DL++QL+KV+ LM MP++EFE++ AC +VF+TW+DE D++Q LLRDI KKKREE + W+ H++LQ RL++++KFR+QHEQLRQVI+RVL+P V +AG KD++ DK + L +++D ++I+EVN AYEIVK IDCLD KE D W+AA+KRY+ERIDRVE+RIA+ LRDLLG +KNANEMFRYFSRFNALFVRPHIRGAI EYQTQLIQRVKDDIEALH KFK QY+SS A M+K RDLPPV+GSIIW RQI RQLNAY+ RVEDVLGK W H +GQ LK +GESFK KLNT+E+FE W +KV++K + V+G IFN+E R + ++ E Q +TVLKL+VNF P+V TLAKEVRNM+ LGFR PL IVN+AH NQLYPFA+SLIESVRTYESTC KIEEH+ QNI LL AGLR+D QL I EG+ + WESYRL YVQK +E + FQEKVDDL+ +EID VK+LETC Y+K FEEI+ +IQ+AVD ++LHQ+SNL QWVS LD VE+RL+VRLEAG+ EW + L+GE E E DD D + +K+ LGG+P++K ++HELRITNQQMHL+PSIEVA Q++L + SW+ I+LNL RI HSRYQVGLE D K YKK+L +L + E+LE A+ A+ +++ +A EYVKTWT+YQ+LWDLQ DQ++ I D VWMNVL+EIKSMR+HFDVAE+QKEFGP+VI FGKVQSKVS+KYDNWHK++L+KFG ++G M LYNEV +AR ++EQQ++++G T+E+VN ITY Q +KRKM WEKQ E R GQNIL RDRFQFP+ WLDSENI GEWSAF+EI+RRK+ ISSQVASLQMK+ EDK+VESKTTE+L NWEK+KP+ GD+ PEEAV+++ ILEGKF RL+EEREN+Q+AKEALELTE GV SE++V A+ EL DLKNVW EL +WE+I +KETPW +VQPRKLRQ ++ + Q+KELP +QYAS+EHV+ L+ Y KVN +VELKSEA+KERHW+MLM+KLNV W+++EL LG VWDIDL KN+ IIREVL IAQGEKALEE+L+Q+TE WKNY L+L +YQ+K ++I+GWDDLF +VKE IN++T+MK SPYFKQFEEEA AWEDRLN+INALFDVWIDVQRRW+YLDGIFAGSADIK+LLP ESQRFQSVSTEFLGLMKKV KSPLV DVLNI+ V RQLERLADLL KIQ+SLGEYLERQRSSFPRFYFVGDEDLLEIIGNSK++ +LQKHFKKMFAGVHSI L+ED +LG+ SKEGEE+ FI PVSI ++P INDWLT +E+EMRVSLA YL A++++ R +++K F+ WLD++ AQ+VVLAAQ+ WSE+V+A+LA S L + V + L +LAD+VLYEQPPVRRRKLEHLIIE+VHQRDV+R L + +S+++FDW+SQMRFYFDPKQTDPLHQ+SI +AN KF YGFEYLGV DRLVQTPLTDRCYLT+TQALE RLGGSPFGPAGTGKTESVK+LG QLGRFVLVFNCDETFDF AMGRIFVGLCQVGAWGCFDEFNRLEERMLSAVSQQIQ IQE LR++ + KD + VELLGKQV V+PDMAIFITMNP YAGRSNLPDNLKKLFRSLAMTQPDRQLIAQVMLYSQGFRTAEVLA K+VPFF+LCDEQLS QSHYDFGLRALKSVLVS+GNVKR+RI++ K+ I+ARGE +NE++IAEQLPEQEILIQSVMETMVPKL+A+DIPLLYSLLTDVFPGV Y + M+ LR ELR+V +LVY++ E N TAG LWV+KVLQLYQIT IHHGLMMVGPSGSGK+MA R LL+ALE ++GIEGVAH+IDPKSI+K+SLYGY+DPNTREWTDGLFTHILR+IIDS+RGES KRQWI+FDGDVDPEWVENLNSVLDDN+LLTLPNGERL IPPNVRIMFEVQDL+YATLATVSRCGMVWFSE+V+ + + HF+ +L+ V + EGEE+ +V G D + SP ++LQ V+SIL P F + GL+++CL Y+ L+HIMDF LR+LTSLFS++KQ IRN++ YN +HSDFP++ +QIE+YV+KSLI +++WSM GD +L RE+L Y++ I+T+ LP G IID+EV + G W AWS KVP IEVETHKIT+ DVVVPTMDTVRHEALLY WLAEHRP++LCGPPGSGKTMTLFSALR LPDMEVVGLNFSSATTPELM+KTFDQYCE RKTPNG+VLAP QLNKWL+FFCDEINLP+ DKYGTQRVISFLRQMVEH GFYR +DMQW+ FERIQFVGACNPPTDPGRKPLSHRFLRHVPVVYVDYPGE SLKQIY TFNRAMLR+LPSLR AD LTNAMV+FFL +Q+RFT DMQPHYIYSPRE++RWVRGIHEALKPL+SLSVEGLVRIWAHEALRLFQDRL+EE ER WTD +I++VALK+FP+I+KE AL RPIL+SNWLSK+Y +V QE LRDYVKARLKVFYEEELDVPLVLFNQVLDHVLRIDRVFRQPQGHLLLIG+SGAGKTTLSRFVSWINGLSVFQVKVHNKYTAEDFD+DLRNVLRR+GCKGEKITFIMDESNV+DSSFLER+NTLLANGEVPGLFEGDE LMTQCKEGA R+GLM+DS EELYKWFT QIC NLHVVFTMNPS DGLKD+ASTSPALFNRCVLNWFGDWS+EAYFQVG+EFT++ D+ER DYKVPD +P +AE LLP+ P +R++V NA VFVH T+H+AN R+QKR GR+ +TPRH+LD IAH++KL EKR+DLEEQQLHL GL+KI +TV+QVEVMQ+SLT+KRQELE MNEAANAKLKQMV DQQEAE++KT Q L+EELA QE F+NEK+ V EL QVEP VN+AKQAV IRK+DIQE+KAMKNPP VK+A+ESIC LLGE +TDW+ IL I+KDTFV SILNFNTDD++D+ RETMKKKYL+NPDYNF+KVN+AS+ACGPMVKW +AQ+ YADILK VEPLRNEL L AA +N+++++ E I LE+SIAKY EEYA LISQAQ IKSDLA+VE+KV RSVAL+ SLSSER+RW+SG+ETFK+QM+TI GDCLLS+AFMAYGGYFDQH+R SLF TWC HL DI FRSDLA VEYLSNPD+RLRWQAN LP D+LCVENAI+L R+NRYPLIIDPSGQAT FLLNEYK KKI KTSFLDD+FRKTLESALRFGTPLLVQDVESYDPILNPVLNREVRRTGGRTLIT+GDQDIDLSPTF+IFLSTRDPSV+F PD+CSRVTFVNFTVTR SLQ QCLNAVLK ERPD+D KRSDLLK QGEFQL+LRHLEKDLLQSLNEA+GNLL++DKII RLETLK+EAA+VAKKVEETDV+M EVE+VS +YVPLAQSCS IYFTLEAMNQ+HFLYQYSLQ +LD+F+ VL N L +V+ + RLKIIT++LFQVTYNR+ARGMLH DQITFA +LARIFLKG ++ L+ EF FLR Q+ I ++ + + Q + ID +K KKL F ++ + + W +V PE+NVP LW ++ +Y+LL+IQA RPDRLLAS + +++ LG+TF + RG LDL SIVE E+ + +PILLCAVQG+DPSGRVED+ASE KQLT IAIGSAEGFSQA+KAINSAAK+GKWVMLKNVHLA WLV LEKK+HS+Q HPNFRLFLTMEI PKLPVNLLRAGR VFEPPPGIK++LLRT +S+ R+SK P ERSRLYFLLAW NA+VQERLRYVPLG+SK+YEF ESD K A DTIDTWVD AAMGRTNLPPEK+PW AL+TLLG IYGGKIDN+FDQRL+ +FL LFTE F+H+F LV D D G +I PE + D+L W++KLPD+QTPSWLGLPN+AEKVLLTNL GQ + GN+LK+Q++ DDE L + K++ V D RP WMRQL S WL LPK+V L RT+EN++DP+YR FEREVNSG NLLASVR+DLE ++ VC G +KPTN +R MM+DL KG+IP W +Y +P +TVIQWI DF R+KQL+ IS+ AA GV ALR IQ+WLGGLFM EAYITATRQ VAQ+N WALEEL+LDV+L G+ G S + L LMG+E +D TL LS I D+ + LKWIR+ +Q E K V LP+Y+N ARS VLFTL ST + S FY+RGVA+ Sbjct: 1 MADSGGDAPPVPAQPTATLADPSALSQYLFKTVSCILEEDDDGAVI-LRSVLEDPTGRDAIKKFISDPQIHSLIVQKLSNKDDDEDGAESGISYSVLTDVRFASSKVQSMVFIKRGAVLEADKSFSVQLRFLNFTDGSPYETLHSMISDAISPFYKSYIRESGRADRDGDK-MAPSVEKTMTELEMGLLHLQQNIDIPEITLSIHPVVAQVVKQKAEAGLRAKASDFEDKMEDAHFLNALQSGVNRWIKEIQKVTKLERDPASGTALQEITFWLNLERSLFRIQEKRESLEVTLTLDILKHAKRFHALVSFEHDTGLQQALDTVNDYNPLMKDFPLNDLLAATELDEIRLAIQSIFTHLRKIRNTKYPVQRALRLVQAISNDLSSQLLKVLGTRRLMHMPFEEFERVMGACSKVFATWDDESDRLQGLLRDIIKKKREEQLRIGWRGAPAHRRLQIRLDHMRKFRHQHEQLRQVIMRVLRPAQTRVTHTDAG--KDELAGNQPGENSSAETTKGPDKISRKVQPLLDASDANAIEEVNLAYEIVKEIDCLDVTKEGTDAWEAAVKRYDERIDRVETRIAARLRDLLGTAKNANEMFRYFSRFNALFVRPHIRGAIREYQTQLIQRVKDDIEALHTKFKAQYSSSEAYHMTKCRDLPPVAGSIIWARQIERQLNAYLHRVEDVLGKGWEHHRDGQLLKTEGESFKAKLNTTEVFEAWVRKVSQKQVLVSGRIFNIEPIRARIATKEGETQTVTVLKLRVNFQPEVNTLAKEVRNMKWLGFRVPLGIVNQAHQTNQLYPFAVSLIESVRTYESTCIKIEEHQRQNIGLLCAGLRRDAQLFILEGMNLIWESYRLGVYVQKFSENMLQFQEKVDDLLQTTREIDLQVKSLETCVYSKAVFEEIIGKIQKAVDELNLHQYSNLPQWVSRLDEEVERRLVVRLEAGVREWTRALRGEKSEAENDDDAQDTHSSQQSKNPLGGEPKLKMIVHELRITNQQMHLHPSIEVAQQELLLSLGSWEGIVLNLPRIQHSRYQVGLEVGGDVHKNYKKILHNLDRADEALEQAHQAILDVVSEAREYVKTWTSYQALWDLQSDQVYGRIGTDTRVWMNVLDEIKSMRQHFDVAESQKEFGPIVIMFGKVQSKVSLKYDNWHKDILSKFGNHLGTEMQELYNEVSKARLDMEQQTVEAGSTSEAVNAITYAQAVKRKMKAWEKQVELYRTGQNILYRDRFQFPSGWLDSENILGEWSAFQEILRRKETAISSQVASLQMKVVAEDKVVESKTTELLLNWEKEKPVEGDIKPEEAVSLLTILEGKFIRLREERENIQRAKEALELTEFGVASPSEQRVQVAIEELQDLKNVWLELSRVWEQIETLKETPWQTVQPRKLRQQLDTMANQIKELPTRLRQYASYEHVKRTLQSYAKVNVLVVELKSEALKERHWKMLMKKLNVDWTMSELTLGHVWDIDLQKNDSIIREVLLIAQGEKALEEFLKQVTEEWKNYTLDLISYQNKCRLIRGWDDLFTRVKERINSLTAMKMSPYFKQFEEEALAWEDRLNRINALFDVWIDVQRRWVYLDGIFAGSADIKILLPQESQRFQSVSTEFLGLMKKVAKSPLVMDVLNISKVDRQLERLADLLSKIQRSLGEYLERQRSSFPRFYFVGDEDLLEIIGNSKNVPRLQKHFKKMFAGVHSIKLNEDSTEVLGLCSKEGEEVIFIKPVSIKDNPVINDWLTLLEREMRVSLATYLAKAIQDLQKLRASGDLEKSGFLDWLDRFHAQLVVLAAQVIWSESVDAALAAMDGKASKGSESPLHKCLASVENMLTVLADSVLYEQPPVRRRKLEHLIIEHVHQRDVIRTLIQNNANSSRSFDWLSQMRFYFDPKQTDPLHQVSIQMANTKFQYGFEYLGVIDRLVQTPLTDRCYLTLTQALEGRLGGSPFGPAGTGKTESVKALGTQLGRFVLVFNCDETFDFHAMGRIFVGLCQVGAWGCFDEFNRLEERMLSAVSQQIQSIQETLRDMACGAKTAGKDGVTVELLGKQVTVHPDMAIFITMNPDYAGRSNLPDNLKKLFRSLAMTQPDRQLIAQVMLYSQGFRTAEVLASKIVPFFQLCDEQLSAQSHYDFGLRALKSVLVSSGNVKRERIRRIKDDILARGETVNESSIAEQLPEQEILIQSVMETMVPKLVAEDIPLLYSLLTDVFPGVVYSPSAMEGLRRELRRVCNETYLVYNESGLFHEAAGHESNSNIFGTTAGSLWVQKVLQLYQITCIHHGLMMVGPSGSGKSMAWRTLLKALERLEGIEGVAHVIDPKSINKESLYGYLDPNTREWTDGLFTHILRKIIDSIRGESLKRQWIIFDGDVDPEWVENLNSVLDDNRLLTLPNGERLGIPPNVRIMFEVQDLRYATLATVSRCGMVWFSEDVIPPELAMEHFIRQLQNVPIDEGEEE-TVGFGLPVVTPESSDQVQSPDFQDLPGVSRESGPVSPTLRLQCDVASILQPHFADGGLVSRCLAYAKDLDHIMDFMPLRSLTSLFSIMKQCIRNIMAYNMTHSDFPMSADQIESYVSKSLIYAIIWSMCGDGRLSTREELGNYLREITTIPLPPTGA--PIIDYEVKLNGEWQAWSQKVPVIEVETHKITSMDVVVPTMDTVRHEALLYLWLAEHRPMILCGPPGSGKTMTLFSALRSLPDMEVVGLNFSSATTPELMMKTFDQYCECRKTPNGLVLAPVQLNKWLVFFCDEINLPNEDKYGTQRVISFLRQMVEHGGFYRTSDMQWLKFERIQFVGACNPPTDPGRKPLSHRFLRHVPVVYVDYPGELSLKQIYGTFNRAMLRLLPSLRSQADALTNAMVDFFLLSQKRFTQDMQPHYIYSPRELSRWVRGIHEALKPLDSLSVEGLVRIWAHEALRLFQDRLIEETERQWTDAHIDDVALKYFPSIDKEAALSRPILFSNWLSKEYCSVEQETLRDYVKARLKVFYEEELDVPLVLFNQVLDHVLRIDRVFRQPQGHLLLIGISGAGKTTLSRFVSWINGLSVFQVKVHNKYTAEDFDDDLRNVLRRAGCKGEKITFIMDESNVLDSSFLERINTLLANGEVPGLFEGDEFAALMTQCKEGATRDGLMVDSHEELYKWFTNQICTNLHVVFTMNPSEDGLKDRASTSPALFNRCVLNWFGDWSIEAYFQVGREFTSKTDMERPDYKVPDFVPAVAEHLLPECPSFREMVANAFVFVHTTLHRANARLQKRTGRSMWVTPRHFLDFIAHFVKLMTEKRSDLEEQQLHLQIGLQKINETVEQVEVMQKSLTQKRQELEQMNEAANAKLKQMVHDQQEAEKRKTMSQRLQEELASQEVFINEKRTLVMNELSQVEPAVNDAKQAVSEIRKRDIQELKAMKNPPATVKLAIESICFLLGEYSTDWRQILTTIMKDTFVPSILNFNTDDITDSIRETMKKKYLNNPDYNFDKVNRASSACGPMVKWAIAQVQYADILKNVEPLRNELKALEQAASKNKEEAKNVESTIESLERSIAKYKEEYAVLISQAQAIKSDLATVEAKVERSVALIKSLSSERSRWESGAETFKSQMSTIFGDCLLSAAFMAYGGYFDQHLRASLFATWCQHLQSVDIRFRSDLALVEYLSNPDERLRWQANDLPNDELCVENAIMLTRFNRYPLIIDPSGQATEFLLNEYKAKKIMKTSFLDDAFRKTLESALRFGTPLLVQDVESYDPILNPVLNREVRRTGGRTLITIGDQDIDLSPTFSIFLSTRDPSVDFPPDVCSRVTFVNFTVTRGSLQTQCLNAVLKAERPDVDSKRSDLLKMQGEFQLRLRHLEKDLLQSLNEAEGNLLDDDKIITRLETLKQEAAEVAKKVEETDVIMSEVETVSQQYVPLAQSCSAIYFTLEAMNQVHFLYQYSLQFLLDVFTCVLTQNARLKDVRESVQRLKIITQDLFQVTYNRVARGMLHNDQITFAVLLARIFLKGQANSKSLSLDTEFDCFLRGQD--IMPKETISKGSASADAEQTRMIDVLK--KKLPSFRNLDSAIAQNRAAFSAWISSVAPEANVPVLWEPTKTEGPTPSWFTQAQTSIYHLLLIQAFRPDRLLASAHRLVSAALGETFMDEARGHLDLLSIVEQEIRSNMPILLCAVQGFDPSGRVEDMASEHHKQLTNIAIGSAEGFSQADKAINSAAKSGKWVMLKNVHLAPGWLVQLEKKLHSVQPHPNFRLFLTMEINPKLPVNLLRAGRAFVFEPPPGIKSSLLRTFASVPAARISKTPAERSRLYFLLAWFNAVVQERLRYVPLGWSKRYEFNESDLKVACDTIDTWVDSAAMGRTNLPPEKVPWAALRTLLGQSIYGGKIDNSFDQRLMETFLSVLFTEASFEHDFPLVRDVDGNAGKHILVPEGSSRDDLLAWINKLPDVQTPSWLGLPNNAEKVLLTNLAITCEQNIRKLLALEQEDSEAGKPEPFGQVMTGNLLKLQEAAADDESLPISAFDRKKSSVVSDARPPWMRQLLGSASAWLSSLPKTVKRLTRTVENLRDPLYRFFEREVNSGSNLLASVRQDLEVISAVCAGERKPTNRYRLMMSDLVKGLIPNDWRQYNVPKTMTVIQWISDFGLRVKQLVAISEAAATGGVSALRDIQIWLGGLFMPEAYITATRQFVAQSNGWALEELYLDVQLVLQGKGGKMTGSSTSGAFTVRDLTLMGAEPLDESTLHLSDTISVDLPLTVLKWIRLSADEQAERYVEKPGSVRLPVYMNGARSLVLFTLRLSTKERSNRFYERGVAL 4752
BLAST of Cytoplasmic dynein 1 heavy chain 1 vs. TrEMBL
Match: A0A4Z2D443 (Cytoplasmic dynein 1 heavy chain 1 isoform 1 OS=Schistosoma japonicum OX=6182 GN=EWB00_004754 PE=4 SV=1) HSP 1 Score: 6628.11 bits (17195), Expect = 0.000e+0 Identity = 3199/4746 (67.40%), Postives = 3853/4746 (81.18%), Query Frame = 3 Query: 87 MADITANLVQPP-DQEITAISLPKFIKYLTLYAFPCMLNDDESKSRKDYELFLSEPQNEECLTKFINDNQVTTLTIQQ--TKRXXXXXXXXXXXXKISNEVNFESNKSQTSIFIKNNQVIEADKTISSQLQVLSYCDGPPFETMHSLVCYGLLPYFXXXXXXXXXXXXXXXXXMVPSVEKKIAELEIGLLHLQQNIEIPEITLTPHPYVAHIIQEKLLQNKEARVSDFEDKFEDTQFLNQLQAGVNRWIKEIQKVTKLNRDPSTGTALQEISFWLNLEHSLDKIQEKRESLEVALTLAILKQAKRFHATTSFDTDTALSSAKIQVKDYNQLMKDFPINDLLSASQLDKISEALQQIFSHLKKVRATKYPVNRIIKLMEALSRDLTTQLMKVISNMHLMSMPYDEFEKIFTACQQVFSTWEDEYDKMQNLLRDIAKKKREEFTKFAWKMNATHKKLQTRLENIKKFRYQHEQLRQVIVRVLKPV-------TKVVPSVEAGVP---------KDQITDKGDKSSTFLPESADTSSIDEVNAAYEIVKVIDCLDFAKEENDEWDAAIKRYEERIDRVESRIASHLRDLLGQSKNANEMFRYFSRFNALFVRPHIRGAIGEYQTQLIQRVKDDIEALHNKFKVQYASSTACKMSKVRDLPPVSGSIIWVRQILRQLNAYMKRVEDVLGKDWAQHIEGQKLKADGESFKLKLNTSELFEEWSKKVAEKSLSVAGSIFNVESTRTVVTVRDREPQKITVLKLKVNFLPDVITLAKEVRNMRALGFRTPLSIVNKAHSANQLYPFAISLIESVRTYESTCSKIEEHKMQNISLLTAGLRKDVQLCIHEGVQITWESYRLDQYVQKLAELVFSFQEKVDDLVIVIKEIDFNVKALETCSYNKQTFEEILIRIQEAVDNMSLHQFSNLAQWVSNLDSLVEQRLIVRLEAGLLEWIKVLKGXXXXXXXXXXXXXXXVNSMAKHRLGGKPQIKKLIHELRITNQQMHLYPSIEVATQDILYQMSSWQNIILNLSRIVHSRYQVGLETESDNQKTYKKLLSSLPNSGESLENAYAAVHNILRDANEYVKTWTNYQSLWDLQGDQLFSLIADDNTVWMNVLEEIKSMRKHFDVAETQKEFGPLVIAFGKVQSKVSMKYDNWHKEVLTKFGQNMGKMMTTLYNEVQRARNELEQQSIDSGGTNESVNFITYTQNIKRKMNTWEKQAEACRAGQNILCRDRFQFPNDWLDSENIQGEWSAFKEIMRRKQETISSQVASLQMKITEEDKIVESKTTEVLGNWEKDKPIAGDLTPEEAVNIIQILEGKFNRLKEERENVQKAKEALELTEIGVKPISEEKVTNALSELHDLKNVWNELKSIWEKIRDMKETPWLSVQPRKLRQDIENLTAQLKELPNSFKQYASFEHVRTLLKMYMKVNASIVELKSEAIKERHWRMLMRKLNVSWSLNELQLGKVWDIDLVKNEEIIREVLAIAQGEKALEEYLRQITEVWKNYVLELTNYQSKSKIIKGWDDLFNKVKEHINNVTSMKASPYFKQFEEEATAWEDRLNKINALFDVWIDVQRRWIYLDGIFAGSADIKVLLPVESQRFQSVSTEFLGLMKKVQKSPLVTDVLNIANVQRQLERLADLLGKIQKSLGEYLERQRSSFPRFYFVGDEDLLEIIGNSXXXXXXXXXXXXMFAGVHSIILSEDEKVILGMMSKEGEELRFISPVSIIEHPRINDWLTAMEKEMRVSLAKYLNVAVKEISGWRTESNIDKDKFMVWLDKYQAQIVVLAAQITWSEAVEASLAS--GVS-------LESTMTVVHSTLNMLADTVLYEQPPVRRRKLEHLIIEYVHQRDVLRALHNDGVSSNKNFDWMSQMRFYFDPKQTDPLHQLSIHVANAKFHYGFEYLGVCDRLVQTPLTDRCYLTMTQALEARLGGSPFGPAGTGKTESVKSLGNQLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLSAVSQQIQGIQEALRELMVSKK----DSINVELLGKQVHVNPDMAIFITMNPGYAGRSNLPDNLKKLFRSLAMTQPDRQLIAQVMLYSQGFRTAEVLAGKVVPFFKLCDEQLSPQSHYDFGLRALKSVLVSAGNVKRDRIKQEKEKIVARGEEINETAIAEQLPEQEILIQSVMETMVPKLIADDIPLLYSLLTDVFPGVEYRQAEMKRLREELRKVSENKFLVY---------------SDEPNTAGYLWVEKVLQLYQITTIHHGLMMVGPSGSGKTMACRVLLQALENIDGIEGVAHIIDPKSISKDSLYGYMDPNTREWTDGLFTHILRRIIDSVRGESNKRQWIVFDGDVDPEWVENLNSVLDDNKLLTLPNGERLAIPPNVRIMFEVQDLKYATLATVSRCGMVWFSEEVLTTGMILTHFLNELKKVQVMEGEEDFSVNQGDTGA----------------DAD-SKISSSPIIQLQTQVSSILAPFFTEDGLIAKCLDYSTTLEHIMDFTRLRALTSLFSMIKQSIRNMIEYNQSHSDFPLNNEQIENYVAKSLISSVVWSMSGDSKLKVREQLSQYIKNISTVDLPTVGGIKNIIDFEVNIQGTWVAWSNKVPQIEVETHKITATDVVVPTMDTVRHEALLYTWLAEHRPVLLCGPPGSGKTMTLFSALRCLPDMEVVGLNFSSATTPELMLKTFDQYCEYRKTPNGIVLAPQQLNKWLIFFCDEINLPDMDKYGTQRVISFLRQMVEHHGFYRITDMQWVSFERIQFVGACNPPTDPGRKPLSHRFLRHVPVVYVDYPGETSLKQIYSTFNRAMLRMLPSLRGYADTLTNAMVEFFLKTQERFTHDMQPHYIYSPREMTRWVRGIHEALKPLESLSVEGLVRIWAHEALRLFQDRLVEEDERHWTDDNINEVALKHFPNINKEEALKRPILYSNWLSKDYSAVTQEELRDYVKARLKVFYEEELDVPLVLFNQVLDHVLRIDRVFRQPQGHLLLIGVSGAGKTTLSRFVSWINGLSVFQVKVHNKYTAEDFDEDLRNVLRRSGCKGEKITFIMDESNVMDSSFLERMNTLLANGEVPGLFEGDELTTLMTQCKEGAIREGLMIDSQEELYKWFTQQICRNLHVVFTMNPSADGLKDKASTSPALFNRCVLNWFGDWSLEAYFQVGKEFTNRLDLERTDYKVPDTLPCIAEGLLPQNPIYRDVVVNALVFVHQTMHQANVRVQKRGGRTAAITPRHYLDLIAHYMKLSAEKRADLEEQQLHLNNGLKKIEQTVDQVEVMQRSLTKKRQELENMNEAANAKLKQMVQDQQEAEQKKTTGQALKEELAKQEQFVNEKQKTVKQELDQVEPTVNEAKQAVQNIRKKDIQEIKAMKNPPNAVKMAVESICLLLGEKTTDWQSILKVIIKDTFVTSILNFNTDDVSDNTRETMKKKYLSNPDYNFEKVNKASNACGPMVKWVLAQISYADILKRVEPLRNELTELSDAAEQNRKKSQETEDLIAQLEKSIAKYTEEYATLISQAQTIKSDLASVESKVGRSVALLGSLSSERTRWDSGSETFKAQMATINGDCLLSSAFMAYGGYFDQHMRTSLFNTWCHHLSEADILFRSDLARVEYLSNPDDRLRWQANSLPADDLCVENAIILRRYNRYPLIIDPSGQATTFLLNEYKEKKITKTSFLDDSFRKTLESALRFGTPLLVQDVESYDPILNPVLNREVRRTGGRTLITLGDQDIDLSPTFTIFLSTRDPSVEFAPDICSRVTFVNFTVTRSSLQNQCLNAVLKIERPDIDQKRSDLLKAQGEFQLKLRHLEKDLLQSLNEAQGNLLENDKIIARLETLKREAADVAKKVEETDVVMQEVESVSTEYVPLAQSCSNIYFTLEAMNQIHFLYQYSLQLMLDIFSSVLINNPELTNVKAASDRLKIITKNLFQVTYNRLARGMLHEDQITFATILARIFLKGSTPIGF-------LENEFQHFLRSQEA-TITSSDSNKQDNLGLTLH------QDQIDSVKRLKKLKVFAKIEEKVKSTKDIKNWTLTVTPESNVPELWVDDNNYNDEKLSKIAKGMYNLLIIQAIRPDRLLASTQKFIASVLGDTFTESVRGTLDLASIVEVEVTACVPILLCAVQGYDPSGRVEDLASEQGKQLTGIAIGSAEGFSQAEKAINSAAKTGKWVMLKNVHLATSWLVSLEKKIHSLQAHPNFRLFLTMEITPKLPVNLLRAGRVLVFEPPPGIKANLLRTLSSINNQRMSKEPVERSRLYFLLAWLNAIVQERLRYVPLGYSKKYEFGESDFKCALDTIDTWVDGAAMGRTNLPPEKIPWVALQTLLGSCIYGGKIDNAFDQRLLNSFLGYLFTEKCFDHNFALVSDAD--DGSNIAFPESTKHTDILQWVHKLPDLQTPSWLGLPNSAEKVLLTNLGQSLIGNILKMQQSLEDDEELVVGQS-KTKRTIEVGDGRPAWMRQLYQSTQTWLQILPKSVTPLQRTIENIKDPMYRCFEREVNSGCNLLASVRKDLEDVAEVCKGAKKPTNHHRSMMADLAKGIIPKMWIRYAIPPGLTVIQWIQDFADRIKQLLHISDTAAKSGVIALRSIQVWLGGLFMAEAYITATRQSVAQNNKWALEELFLDVEL----------GEGKVDSNTCVITGLRLMGSEIVDPRTLKLSTLIYKDIDICRLKWIRVEKSQQLEGSSAKD-KVCLPIYLNAARSTVLFTLYFSTTDSSYDFYKRGVAI 14048 MAD + + V P ++ F KY+ + C L ++ S E L++P N+E + KFI+D Q+ ++ +Q+ T+ +++E ++ + + EV F ++K Q+ +FIK V+EADK+ SSQL+ L++ DG P+ET+HS + + P++KSYI++ G+ M PSVEK + ELE+GLLHLQQNI+IPEITL+ HP VA II+++ + K A+ SDFEDK +D QFLN LQ+GVNRWIKEIQKVTKL+RDPS+GTALQEI+FWLNLE SL +IQEKRESLEV LTL ILK AKRFHA SFDTDT L A V DYN LMKDFP+NDLLSA++LDKI A+Q IF+HL+K+R TKYP+ R ++L+EA+SRDLT+QL+KV+ LM MP++EFE++ AC +VFSTW+DEYD++Q+L+RDI KKKR+E + W+ N H++LQ RL+ ++KFR+QHEQLRQVIVRVL+P TK P+ V ++ K L +++D ++I+EVN AYEIVK IDCLD KE ++ W+AA+KRY+ERIDRVE+RIA+ LRDLLG +KNANEMFRYFSRFNALFVRPHIRGAI EYQTQLIQRVKDDIEALH KF++QY SS A M+K+RDLPPV+GSIIW RQI RQLNAY++RVEDVLGK W H EGQ LKADG+SFK KLNT+ELFE+WS+KV +K +SV+G IFN+E R V ++ E Q ITVLKLKVNF +VITLAKEVRNM+ LGFR PL IVN+AH NQLYP+AISLIESVRTYES CSKIEE++ QNI LL AG+R++VQL I EG+ + WESYRL +VQ+ AE V FQEKVDDL++ +EID VKALETC ++K FEEIL +IQ++VD ++LHQ+SNL QWV+ LD VE RL+ RLEAG+ EW +VL G+ + + + D +K+RLGG+PQIK L+HELRITNQQ+HL+PSIEVA +++ +S+W++I+L+L RI HSRYQVG+++E+D QK YKKL+ L N+GE L A+ A+ + DA EYVKTWT+YQ+LWDLQ DQ++ + D VWM++L+EIKSMR+HFDVAETQKEFGP++I FGKVQSKVS+KYDNWHK++L+KFG ++G M L+++V +AR +LEQQ+I++G T E+VN ITYTQ +KRKM WEKQ E R+GQNIL RDRFQFP++WLDSENI GEWSAF+EI+RRK+ +I +QVASLQMK+ EDKIVE KT+E+L +WEK+KPIAG+L PEEAVN + ILEGKFNRL+EER+N+Q+AKEALELTE GV +E++V A EL DLKNVW EL +WE+I MKETPW +VQPRKLRQ ++ L QLKELP +QY+S+EHV+ L+ Y K N IVELKSEA+K+RHW+ LM+KLNV W+++EL LG +W++DL +NE +I+EVL +AQGEKALEE+L+Q+TEVWKNY LEL YQ K ++I+GWDDLFN+VKEHIN++++MK SPYFKQFEEEA AWEDRLN+INALFDVWIDVQRRW+YLDGIFAGSADIKVLLP ESQRFQSVSTEFLGLMKKV KSPLV DVLN +NVQRQLERLADLL KIQ+SLGEYLERQRSSFPRFYFVGDEDLLEIIGNSK++ +LQKHFKKMFAGV+SI L+ED ILG+ SKEGEE+ + P+SI ++P INDWLT +E+EMR SLA YL A++E+ +T +I+K F+ WLDK+QAQ+VVLAAQ+ WSEAV+ +L + G S L+ +T V L +LAD VLYEQPPVRR+KLEHLIIE+VHQRDV+R+L V+S ++FDW+SQMRFYFDPKQ+DPL Q+SI +ANAKF YGFEYLG+ DRLVQTPLTDRCYLTMTQALEARLGGSPFGPAGTGKTESVK+LG QLGRFVLVFNCDETFDF AMGRIFVGLCQVGAWGCFDEFNRLEERMLSAVSQQ+QGIQE LR++ S+K +S+ VELLGKQV+V+PDMAIFITMNPGYAGRSNLPDNLKKLFRSLAMTQPDRQLIAQVMLYSQGFRTAE LA K+VPFF+LCDEQLS QSHYDFGLRALKSVLVSAG+VKR+RI++ KE I+ARGE +NET+IAE LPEQEILIQSVMETMVPKL+A+DIPLLYSLLTDVFPGV Y Q+ M++LR ELR+V E +LVY S N++ LWV+KVLQLYQIT IHHGLMMVGPSGSGK+ A RVLL+ALE ++G+EGVAH+IDPKSISK+SLYG +DPNTREW+DGLFTH+LR+IIDS+RGES KRQWI+FDGDVDPEWVENLNSVLDDNKLLTLPNGERL+IPPNVRIMFEVQDL+YATLATVSRCGMVWFS++V+ G+++ HFL +L+ V++ EGEE+F T DA + ++ S +QLQ ++SIL PFF E GL+ +CL+Y+ L+HIMDF LR+LTSLFS++KQ IR ++ YN +H DFP++ +Q+E+YV K LI+ ++WS+ GD KL VREQL +I+ I+TV +P G +ID+EV++ G W W+ KVP IE+ETHKIT+ DVVVPT+DTVRHEALLY WLAEHRP++LCGPPGSGKTMTLFSALR LPDMEVVGLNFSSATTPELMLKTFDQYCEYRKTPNG+VLAP QLNKWLIFFCDEINLP+ DKYGTQRVISFLRQMVEH GFY+ TDMQWV FERIQFVGACNPPTDPGRKPLSHRFLRHVP+VYVDYPGETSLKQIY TFNRAMLR+LPSLR AD LTNAMVEFFL +Q+RFT DMQPHY+YSPRE++RWVRGIHEALKPL+SL +EGLVRIWAHEALRLFQDRL+EE ER WTD NI+EVA+K+FP I++ AL+RPIL+SNWLSKDYS V Q LRDY+KARLKVFYEEELDVPLVLFNQVLDHVLRIDRVFRQPQGHLLLIGVSGAGKTTLSRFVSWINGLSVFQVKVHNKYTAEDFD+DLRNVLRR+GCKGEKITFIMDESNV+DSSFLER+NTLLANGEVPGLFEGDE + LMTQCKEGA REGLMIDS EELYKWFT QIC NLHVVFTMNPSADGLKD+ASTSPALFNRCVLNWFGDWSLEAY+QVGKEFT ++D+ER D+K PD +P + EGLLP+ P +R++V NA VFVHQT+H+AN+R+QKRG RT ITPRH+LD IAH++ L EKR+DLEEQQLHL+ GL+KI++TV+QVEVMQ+SLT+K ELE MN AAN KLKQMVQDQQEAE+KKT Q L+EELA QE ++NEK+ V EL QVEP V +AKQAV+ IRK+DIQEI+AMKNPP+ VKMAVESICLLLGE ++DW ILK ++KD+FV SI+NFNTDDV+D+ RETMKKKY+SNPDYNFEKVN+AS+ACGPMVKW +AQI+YADILK+VEPLRNEL L AA N+++++ E IA LEKSIAKY EEYA LISQAQ IKSDLA+VE+KV RSVAL+ SL +ER RW+SGSETFK+QM+TI GDCLLS+AFMAYGGYFDQH R+ L TWC HL+ DI FR+DLA VEYLSNPD+RLRWQAN+LP D+LCVENAIILRR+NRYPLIIDPSGQAT FLLNEYK KKI KTSFLDD+FRKTLESALRFGTPLLVQDVESYD ILNPVLNREVRRTGGRTLIT+GDQDIDLSPTF IFLSTRDPSV+F D+CSRVTFVNFTVTR SLQ+QCLNA LK ERPD+D KRSDLLK QGEFQLKLRHLEKDLLQSLN+A+GNLL++DKII LETLK+EA +VAKKVEETDV+M+EVESVS +YV LAQSCS+IYFTL+AMNQ+HFLYQYSLQ +LDIF+ VL N L +VK + RL+IITK+LFQVTYNR+ARGML++DQIT + +LARIF+KG G LENEF FL QE SDS + L L + ++D+ K L KL I +K + K+W +V+PE++VPELW N+ ND + +++LL+IQ RPDR+LA+ F+ + G F ES RG LDL SIVE E+ A +PILLCA QG+DPSGRVEDLA+E KQLT IAIGSAEGFSQA+KAINSAAK GKWVMLKNVHLA+ WL+ LEKK+HS+Q +PNFRLFLTMEI PKLPVN+LR+GRVLVFEPPPGIKA+LLRT +++ R+S+ P ER+RLYFLLAW NA+VQERLRYVPLG+SK+YEF ESD K A DT+DTWVD AA+GR+NL P+K+PW AL+TLLG CI+GGKIDN FDQRLL +FL LFTE F+H+F LV D D G NI P+ + ++L W+ KLPD+QTPSWLGLPN+AEKVLLTNLG +I N+LK+Q+++ DD+ +VVG K+++ D RP WMRQL S TWL +LP ++ PL R+ EN++DP+YR FEREVN+GCNLL +VR DL V VC G +KPTNHHR +M+DL KGIIPK W RY P GLTVIQWI DF R++QLL +++T++ +GV LR IQVWLGGLFM EAY+TATRQ VAQ+N WALEEL+LDVEL +S V+ L LMG+E ++ T++LS I ++ + LKWI++ ++++E K+ V LP+Y+N +R+ VLFTL +++SS FY+RGVA Sbjct: 1 MADASVDPVANPLPPTVSLADTLVFSKYV--HKIVCTLLEESSDGALVLETTLNDPNNQELIKKFISDAQIHSIVVQKLSTRDDDDESTDSCVSYSVLLEVRFTNSKVQSIVFIKRGGVLEADKSFSSQLRFLNFSDGSPYETLHSTISNAISPFYKSYIRESGRADRDGDK-MAPSVEKTMTELEMGLLHLQQNIDIPEITLSVHPLVAQIIKQRAEEGKRAKTSDFEDKLDDAQFLNALQSGVNRWIKEIQKVTKLDRDPSSGTALQEITFWLNLERSLFRIQEKRESLEVTLTLDILKHAKRFHALVSFDTDTGLQRALGTVNDYNPLMKDFPLNDLLSATELDKIRLAVQSIFTHLRKIRNTKYPLQRALRLIEAISRDLTSQLLKVLGTRRLMHMPFEEFERVMAACFEVFSTWDDEYDRLQSLMRDIIKKKRDEQLRMIWRSNPAHRRLQLRLDQMRKFRHQHEQLRQVIVRVLRPARSAQVDKTKDAPAESNDVSTINGAVVNESSKVAQKAVGKEQPLLDASDANAIEEVNLAYEIVKEIDCLDVTKEGSEVWEAAVKRYDERIDRVETRIAARLRDLLGTAKNANEMFRYFSRFNALFVRPHIRGAIREYQTQLIQRVKDDIEALHAKFRIQYTSSKAYHMTKLRDLPPVAGSIIWARQIERQLNAYLRRVEDVLGKGWEHHREGQLLKADGDSFKAKLNTNELFEDWSRKVQQKQISVSGRIFNIEPIRAKVATKEGETQTITVLKLKVNFQLEVITLAKEVRNMKWLGFRVPLGIVNRAHQTNQLYPYAISLIESVRTYESACSKIEENQRQNIGLLCAGMRREVQLLIAEGISLVWESYRLGLFVQRFAETVLQFQEKVDDLLVTTREIDREVKALETCVFSKSVFEEILGKIQKSVDELNLHQYSNLPQWVARLDEEVEHRLVARLEAGIFEWTRVLLGQKDQFDASELDDTHS-TPQSKNRLGGEPQIKALVHELRITNQQIHLHPSIEVARHELIVNLSAWESIVLSLPRIQHSRYQVGIDSETDTQKNYKKLIYKLENAGEVLAKAHEAIVQVTGDAKEYVKTWTSYQALWDLQSDQVYGRLGSDTQVWMSLLDEIKSMRQHFDVAETQKEFGPIIIMFGKVQSKVSLKYDNWHKDILSKFGSHLGSEMQDLFSQVSKARLDLEQQAIEAGSTGEAVNAITYTQAVKRKMKVWEKQVELYRSGQNILYRDRFQFPSNWLDSENILGEWSAFQEILRRKENSIGTQVASLQMKVVAEDKIVEGKTSELLSSWEKEKPIAGNLKPEEAVNQLTILEGKFNRLREERDNIQRAKEALELTESGVLSPTEQRVQVAFEELQDLKNVWLELSHVWEQIELMKETPWQTVQPRKLRQQLDALAGQLKELPARLRQYSSYEHVKRTLQNYAKSNVMIVELKSEALKDRHWKTLMKKLNVDWTMSELTLGHIWELDLQQNEAVIKEVLLVAQGEKALEEFLKQVTEVWKNYTLELIPYQDKCRLIRGWDDLFNRVKEHINSLSAMKLSPYFKQFEEEALAWEDRLNRINALFDVWIDVQRRWVYLDGIFAGSADIKVLLPQESQRFQSVSTEFLGLMKKVSKSPLVMDVLNTSNVQRQLERLADLLSKIQRSLGEYLERQRSSFPRFYFVGDEDLLEIIGNSKNVPRLQKHFKKMFAGVNSIKLNEDSTEILGLSSKEGEEVILVKPISIKDNPVINDWLTMLEREMRFSLATYLGHAIQELQKLKTAQDIEKSGFLSWLDKFQAQLVVLAAQVIWSEAVDNALNTMKGQSTSTQDSPLQKCLTSVEGMLTVLADCVLYEQPPVRRQKLEHLIIEHVHQRDVIRSLIRSDVNSPRSFDWLSQMRFYFDPKQSDPLRQVSIQMANAKFQYGFEYLGLNDRLVQTPLTDRCYLTMTQALEARLGGSPFGPAGTGKTESVKALGTQLGRFVLVFNCDETFDFHAMGRIFVGLCQVGAWGCFDEFNRLEERMLSAVSQQVQGIQETLRDMACSQKSSTKESVTVELLGKQVNVHPDMAIFITMNPGYAGRSNLPDNLKKLFRSLAMTQPDRQLIAQVMLYSQGFRTAEKLASKIVPFFQLCDEQLSAQSHYDFGLRALKSVLVSAGHVKRERIRKLKEDILARGETVNETSIAESLPEQEILIQSVMETMVPKLVAEDIPLLYSLLTDVFPGVHYTQSAMEKLRRELRRVCEEMYLVYDESGVDKQNSDDVVLSSGGNSSASLWVQKVLQLYQITCIHHGLMMVGPSGSGKSTAWRVLLKALERVEGVEGVAHVIDPKSISKESLYGCLDPNTREWSDGLFTHVLRKIIDSIRGESFKRQWIIFDGDVDPEWVENLNSVLDDNKLLTLPNGERLSIPPNVRIMFEVQDLRYATLATVSRCGMVWFSDDVVAPGLVMQHFLLQLQSVRIDEGEEEFLGFSSTTIPPVPTSPSSSRHPSLIDDAPPTNVTVSASMQLQRDIASILTPFFAEGGLVGRCLEYAKDLDHIMDFMPLRSLTSLFSILKQCIRRILTYNMTHPDFPMSLDQVESYVTKCLITGIIWSLCGDGKLHVREQLGSFIREITTVPMPPSG--TPVIDYEVSLSGEWQPWAQKVPVIEIETHKITSMDVVVPTLDTVRHEALLYMWLAEHRPMILCGPPGSGKTMTLFSALRSLPDMEVVGLNFSSATTPELMLKTFDQYCEYRKTPNGLVLAPVQLNKWLIFFCDEINLPNEDKYGTQRVISFLRQMVEHGGFYQTTDMQWVKFERIQFVGACNPPTDPGRKPLSHRFLRHVPIVYVDYPGETSLKQIYGTFNRAMLRLLPSLRPQADALTNAMVEFFLMSQKRFTQDMQPHYVYSPRELSRWVRGIHEALKPLDSLPLEGLVRIWAHEALRLFQDRLIEESERQWTDFNIDEVAVKYFPTIDRVAALQRPILFSNWLSKDYSPVEQGPLRDYIKARLKVFYEEELDVPLVLFNQVLDHVLRIDRVFRQPQGHLLLIGVSGAGKTTLSRFVSWINGLSVFQVKVHNKYTAEDFDDDLRNVLRRAGCKGEKITFIMDESNVLDSSFLERINTLLANGEVPGLFEGDEFSALMTQCKEGAAREGLMIDSHEELYKWFTSQICTNLHVVFTMNPSADGLKDRASTSPALFNRCVLNWFGDWSLEAYYQVGKEFTIKMDMERPDFKAPDIIPSVVEGLLPECPSFREMVANAFVFVHQTLHEANLRLQKRGARTMWITPRHFLDFIAHFVSLMTEKRSDLEEQQLHLHIGLQKIKETVEQVEVMQKSLTQKSLELEQMNNAANDKLKQMVQDQQEAEKKKTMSQRLQEELANQELYINEKRSLVMNELSQVEPAVADAKQAVEGIRKRDIQEIRAMKNPPSVVKMAVESICLLLGEGSSDWNQILKTLVKDSFVPSIINFNTDDVTDSIRETMKKKYISNPDYNFEKVNRASSACGPMVKWAIAQINYADILKKVEPLRNELKTLEAAATTNKEEAKSNEVTIAALEKSIAKYKEEYAVLISQAQAIKSDLATVEAKVARSVALIKSLGNERARWESGSETFKSQMSTIFGDCLLSAAFMAYGGYFDQHFRSRLLETWCRHLTSVDIRFRNDLALVEYLSNPDERLRWQANALPDDELCVENAIILRRFNRYPLIIDPSGQATEFLLNEYKSKKIMKTSFLDDAFRKTLESALRFGTPLLVQDVESYDSILNPVLNREVRRTGGRTLITIGDQDIDLSPTFRIFLSTRDPSVDFPADVCSRVTFVNFTVTRGSLQSQCLNAALKAERPDVDAKRSDLLKMQGEFQLKLRHLEKDLLQSLNDAKGNLLDDDKIITHLETLKQEAGEVAKKVEETDVIMKEVESVSHQYVALAQSCSSIYFTLQAMNQVHFLYQYSLQFLLDIFNCVLTQNVRLKDVKDCAQRLQIITKDLFQVTYNRVARGMLYKDQITLSVLLARIFIKGQVS-GMSNIQQNGLENEFTCFLHGQEPLKKGGSDSTNDHDTTLQLANKGQCLKSKLDAFKNLDKL-----ISQK---SVAFKSWIESVSPEADVPELWEAPNSPND-WFGVVRNQLFSLLLIQTFRPDRILAAAHLFVITCFGPNFMESARGHLDLMSIVEHEIRANMPILLCAAQGFDPSGRVEDLANEYNKQLTSIAIGSAEGFSQADKAINSAAKNGKWVMLKNVHLASGWLIQLEKKLHSVQPNPNFRLFLTMEINPKLPVNVLRSGRVLVFEPPPGIKASLLRTFANVPANRISRAPAERARLYFLLAWFNAVVQERLRYVPLGWSKRYEFNESDLKVACDTVDTWVDMAALGRSNLSPDKVPWSALRTLLGQCIFGGKIDNLFDQRLLETFLNVLFTESSFEHDFPLVRDVDGQSGKNIVIPDGSSRDELLSWIEKLPDVQTPSWLGLPNNAEKVLLTNLGSEMISNLLKLQEAISDDDSVVVGTGLDRKKSVVDTDPRPLWMRQLLTSATTWLSLLPDTLKPLIRSPENLRDPLYRFFEREVNTGCNLLTTVRSDLSVVIAVCSGERKPTNHHRLLMSDLTKGIIPKDWRRYTFPGGLTVIQWINDFVSRLRQLLLVAETSSSNGVAGLRDIQVWLGGLFMPEAYVTATRQFVAQSNGWALEELYLDVELVMVEKSKKPPQLPSSNSGAFVVRDLWLMGAEPLNSTTIQLSNSISVELPMTVLKWIKLSTNERVERFLEKEGSVRLPVYMNGSRNVVLFTLQLMSSESSNRFYERGVAF 4730
BLAST of Cytoplasmic dynein 1 heavy chain 1 vs. Ensembl Cavefish
Match: DYNC1H1 (dynein cytoplasmic 1 heavy chain 1 [Source:HGNC Symbol;Acc:HGNC:2961]) HSP 1 Score: 5025.68 bits (13035), Expect = 0.000e+0 Identity = 2403/3758 (63.94%), Postives = 2984/3758 (79.40%), Query Frame = 3 Query: 2820 VEQRLIVRLEAGLLEWIKVLKGXXXXXXXXXXXXXXXVNSMAKHRLGGKPQIKKLIHELRITNQQMHLYPSIEVATQDILYQMSSWQNIILNLSRIVHSRYQVGLETE-SDNQKTYKKLLSSLPNSGESLENAYAAVHNILRDANEYVKTWTNYQSLWDLQGDQLFSLIADDNTVWMNVLEEIKSMRKHFDVAETQKEFGPLVIAFGKVQSKVSMKYDNWHKEVLTKFGQNMGKMMTTLYNEVQRARNELEQQSIDSGGTNESVNFITYTQNIKRKMNTWEKQAEACRAGQNILCRDRFQFPNDWLDSENIQGEWSAFKEIMRRKQETISSQVASLQMKITEEDKIVESKTTEVLGNWEKDKPIAGDLTPEEAVNIIQILEGKFNRLKEERENVQKAKEALELTEIGVKPISEEKVTNALSELHDLKNVWNELKSIWEKIRDMKETPWLSVQPRKLRQDIENLTAQLKELPNSFKQYASFEHVRTLLKMYMKVNASIVELKSEAIKERHWRMLMRKLNVSWSLNELQLGKVWDIDLVKNEEIIREVLAIAQGEKALEEYLRQITEVWKNYVLELTNYQSKSKIIKGWDDLFNKVKEHINNVTSMKASPYFKQFEEEATAWEDRLNKINALFDVWIDVQRRWIYLDGIFAGSADIKVLLPVESQRFQSVSTEFLGLMKKVQKSPLVTDVLNIANVQRQLERLADLLGKIQKSLGEYLERQRSSFPRFYFVGDEDLLEIIGNSXXXXXXXXXXXXMFAGVHSIILSEDEKVILGMMSKEGEELRFISPVSIIEHPRINDWLTAMEKEMRVSLAKYLNVAVKEISGWRTESNIDKDKFMVWLDKYQAQIVVLAAQITWSEAVEASLAS------GVSLESTMTVVHSTLNMLADTVLYEQPPVRRRKLEHLIIEYVHQRDVLRALHNDGVSSNKNFDWMSQMRFYFDPKQTDPLHQLSIHVANAKFHYGFEYLGVCDRLVQTPLTDRCYLTMTQALEARLGGSPFGPAGTGKTESVKSLGNQLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLSAVSQQIQGIQEALRELMVSKKD---SINVELLGKQVHVNPDMAIFITMNPGYAGRSNLPDNLKKLFRSLAMTQPDRQLIAQVMLYSQGFRTAEVLAGKVVPFFKLCDEQLSPQSHYDFGLRALKSVLVSAGNVKRDRIKQEKEKIVARGEEINETAIAEQLPEQEILIQSVMETMVPKLIADDIPLLYSLLTDVFPGVEYRQAEMKRLREELRKVSENKFLVYSDEPNTAGYLWVEKVLQLYQITTIHHGLMMVGPSGSGKTMACRVLLQALENIDGIEGVAHIIDPKSISKDSLYGYMDPNTREWTDGLFTHILRRIIDSVRGESNKRQWIVFDGDVDPEWVENLNSVLDDNKLLTLPNGERLAIPPNVRIMFEVQDLKYATLATVSRCGMVWFSEEVLTTGMILTHFLNELKKVQVMEGEEDFSVNQGDTGADADSKISSSPIIQLQTQVSSILAPFFTEDGLIAKCLDYSTTLEHIMDFTRLRALTSLFSMIKQSIRNMIEYNQSHSDFPLNNEQIENYVAKSLISSVVWSMSGDSKLKVREQLSQYIKNISTVDLPTVGGIKNIIDFEVNIQGTWVAWSNKVPQIEVETHKITATDVVVPTMDTVRHEALLYTWLAEHRPVLLCGPPGSGKTMTLFSALRCLPDMEVVGLNFSSATTPELMLKTFDQYCEYRKTPNGIVLAPQQLNKWLIFFCDEINLPDMDKYGTQRVISFLRQMVEHHGFYRITDMQWVSFERIQFVGACNPPTDPGRKPLSHRFLRHVPVVYVDYPGETSLKQIYSTFNRAMLRMLPSLRGYADTLTNAMVEFFLKTQERFTHDMQPHYIYSPREMTRWVRGIHEALKPLESLSVEGLVRIWAHEALRLFQDRLVEEDERHWTDDNINEVALKHFPNINKEEALKRPILYSNWLSKDYSAVTQEELRDYVKARLKVFYEEELDVPLVLFNQVLDHVLRIDRVFRQPQGHLLLIGVSGAGKTTLSRFVSWINGLSVFQVKVHNKYTAEDFDEDLRNVLRRSGCKGEKITFIMDESNVMDSSFLERMNTLLANGEVPGLFEGDELTTLMTQCKEGAIREGLMIDSQEELYKWFTQQICRNLHVVFTMNPSADGLKDKASTSPALFNRCVLNWFGDWSLEAYFQVGKEFTNRLDLERTDYKVPDTLPCIAEGLLPQNPIYRDVVVNALVFVHQTMHQANVRVQKRGGRTAAITPRHYLDLIAHYMKLSAEKRADLEEQQLHLNNGLKKIEQTVDQVEVMQRSLTKKRQELENMNEAANAKLKQMVQDQQEAEQKKTTGQALKEELAKQEQFVNEKQKTVKQELDQVEPTVNEAKQAVQNIRKKDIQEIKAMKNPPNAVKMAVESICLLLGEKTTDWQSILKVIIKDTFVTSILNFNTDDVSDNTRETMKKKYLSNPDYNFEKVNKASNACGPMVKWVLAQISYADILKRVEPLRNELTELSDAAEQNRKKSQETEDLIAQLEKSIAKYTEEYATLISQAQTIKSDLASVESKVGRSVALLGSLSSERTRWDSGSETFKAQMATINGDCLLSSAFMAYGGYFDQHMRTSLFNTWCHHLSEADILFRSDLARVEYLSNPDDRLRWQANSLPADDLCVENAIILRRYNRYPLIIDPSGQATTFLLNEYKEKKITKTSFLDDSFRKTLESALRFGTPLLVQDVESYDPILNPVLNREVRRTGGRTLITLGDQDIDLSPTFTIFLSTRDPSVEFAPDICSRVTFVNFTVTRSSLQNQCLNAVLKIERPDIDQKRSDLLKAQGEFQLKLRHLEKDLLQSLNEAQGNLLENDKIIARLETLKREAADVAKKVEETDVVMQEVESVSTEYVPLAQSCSNIYFTLEAMNQIHFLYQYSLQLMLDIFSSVLINNPELTNVKAASDRLKIITKNLFQVTYNRLARGMLHEDQITFATILARIFLKGSTPIGFLENEFQHFLRSQEATITSSDSNKQDNLGLTLHQDQIDSVKRLKKLKVFAKIEEKVKSTKDIKNWTLTVTPESNVPELWVDDNNYNDEKLSKIAKGMYNLLIIQAIRPDRLLASTQKFIASVLGDTFTESVRGTLDLASIVEVEVTACVPILLCAVQGYDPSGRVEDLASEQGKQLTGIAIGSAEGFSQAEKAINSAAKTGKWVMLKNVHLATSWLVSLEKKIHSLQAHPNFRLFLTMEITPKLPVNLLRAGRVLVFEPPPGIKANLLRTLSSINNQRMSKEPVERSRLYFLLAWLNAIVQERLRYVPLGYSKKYEFGESDFKCALDTIDTWVDGAAMGRTNLPPEKIPWVALQTLLGSCIYGGKIDNAFDQRLLNSFLGYLFTEKCFDHNFALVSDADDGSNIAFPESTKHTDILQWVHKLPDLQTPSWLGLPNSAEKVLLTNLGQSLIGNILKMQQSLEDDEELVVGQSKTKRTIEVGDGRPAWMRQLYQSTQTWLQILPKSVTPLQRTIENIKDPMYRCFEREVNSGCNLLASVRKDLEDVAEVCKGAKKPTNHHRSMMADLAKGIIPKMWIRYAIPPGLTVIQWIQDFADRIKQLLHISDTAAKSGVIALRSIQVWLGGLFMAEAYITATRQSVAQNNKWALEELFLDVELGEGK---VDSNTCVITGLRLMGSEIVDPRTLKLSTLIYKDIDICRLKWIRVEKSQQLEGSSAKDKVCLPIYLNAARSTVLFTLYF--STTDSSYDFYKRGVAI 14048 +E+ L VRL+AGL W +VL+G+ + + D DT+ H+ GG+P+IK ++HELRITNQ ++L P IE + +M +W+ +IL+L RI RYQVG+ E S+ +K Y+ L+ +P+ +LE AY AV + + +YVK W YQ LWD+Q + +++ + +D W +L +I+ R FD AET+KEFGP+VI +GKVQSKV++KYD+WHKEVL+KFGQ +G M ++++ ++R ELEQ S+D+ T+++V FITY Q +KRK+ +EKQ + R GQ +L + RFQFP WL +NI+GEW AF +IM+RK I QVA+LQMKI +ED+ VE++T+++L +WEK KP+AG+L PEEA+ + I EGKF RLK++RE KAKEALELT+ G+ SEE+V AL EL DLK VW+EL +WE+I MKE PW+SVQPRKLRQ ++ L QLK P +QYAS+E+V+ LLK Y+KVN ++ELKSEA+K+RHW+ LM++L+V+W L+EL LG++WD+DL KNE ++++VL +AQGE ALEE+L+QI EVW +Y L+L NYQ+K ++I+GWDDLFNKVKEHIN+V++MK SPY+K FEE+A +WED+LN+I ALFDVWIDVQRRW+YL+GIF GSADIK LLPVE+QRFQS+STEFL LMKKV KSPLV DVLNI VQR LERLADLLGKIQK+LGEYLER+RSSFPRFYFVGDEDLLEIIGNSK++ KLQKHFKKMFAGV SI+L+ED +LG+ S+EGEE+ + +PVSI EHP+IN+WLT +EKEMRV+LAK L +V E+ + + ID ++ W+D+YQAQ+VVL+AQI WSE VE +L + L+ +T V +TLN+LADTVL EQPP+RR+KLEHLI E VHQRDV R L + + + K+F+W+SQMRFYFDPKQTD L QLSI +ANAKF+YGFEYLGV ++LVQTPLTDRCYLTMTQALEARLGGSPFGPAGTGKTESVK+LG+QLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLSAVSQQ+Q IQ ALRE +D + ELL KQV V+ +MAIFITMNPGYAGRSNLPDNLKKLFRSLAMT+PDRQLIAQVMLYSQGFRTAE LA K+VPFFKLCDEQLS QSHYDFGLRALKSVL+SAGNVKR+RI++ K + RGE+++E IAE LPEQEILIQSV ETMVPKL+A+DIPLL+SLL+DVFPGV+Y + EM LREEL+KV +L Y D + G +WVEKVLQLYQIT I+HGLMMVGPSGSGKTMA RVLL+ALE ++G+EGVAHIIDPK+ISKD LYG +DPNTREWTDGLFTH+LR+IID+VRGE KRQWI+FDGDVDPEWVENLNSVLDDNKLLTLPNGERL++PPNVRIMFEVQDLKYATLATVSRCGMVWFSE+VL+T MI +FL ++ + + EGE++ + G + + + ++SP++Q+Q V++IL P+FT GL+ K L++++ +EHIMDFTRLR + SLFSM+ Q+ RN+ YN +H DFP+ +Q+E Y+ K LI +V+WS SGD KLK+R +L +YI+ I+TV LP+ + IID+EV I G W +W KVPQIEVETHK+ A DVVVPT+DTVRHEALLYTWLAEH+P++LCGPPGSGKTMTLFSALR LPDMEVVGLNFSSATTPEL+LKTFD YCEYR+TPNG+VLAP QL KWL+ FCDEINLPDMDKYGTQRVISF+RQMVEH GFYR +D WV ERIQFVGACNPPTDPGRKPLSHRFLRHVPVVYVDYPG SL QIY TFNRAMLR++P+LR YA+ LT AMVEF+ +QERFT D QPHYIYSPREMTRWVRGI EAL+PLE+L VEGL+RIWAHEALRLFQDRLVE++ER WTD+NI+ VALKHFPNI++E+AL RPILYSNWLSKDY V QEELRDYVKARLKVFYEEELDVPLVLFN+VLDHVLRIDR+FRQPQGHLLLIGVSGAGKTTLSRFV+W+NGLSV+Q+KVH KYT EDFDEDLR VLRRSGCK EKI FIMDESNV+DS FLERMNTLLANGEVPGLFEGDE TLMTQCKEGA +EGLM+D+ EELYKWFT Q+ RNLHVVFTMNPS++GLKD+A+TSPALFNRCVLNWFGDWS EA +QVGKEFT+++DLE+ +YKVPD +P + + LPQ P +R+ +VN VFVHQT+HQAN R+ KRGGRT AITPRHYLD I HY L EKR++LEEQQ+HLN GL+KI++TVDQVE ++R L K QELE N AAN KLK+MV+DQQEAE+KK Q ++E + KQ++ + +KQ VKQ+LDQVEP V EA+ AV++I+K+ + E+++M NPP AVK+A+ESICLLLGE TTDW+ I +I+++ F+ +I+NF+ +++SD RE MKK Y+SNP YN+E+VN+AS ACGPMVKW +AQ++YAD+LKRVEPLRNEL +L D A+ N+ K++E E +I LE SIA+Y EEYA LIS+AQ IK+DLA+VE+KV RS ALL SLS+ER RW+ SETFK QM+TI GDCLLS+AF+AY GYFDQ MR +LF TW HHL +A+I FR+D+AR EYLSN D+RLRWQANSLPADDLC ENAI+L+R+NRYPLIIDPSGQAT F++NEYK++KIT+TSFLDD+FRK LESALRFG PLLVQDVESYDPILNPVLNREVRRTGGR LITLGDQDIDLSP+F IFLSTRDP+VEF PD+CSRVTFVNFTVTRSSLQ+QCLN VLK ERPD+D+KRSDLLK QGEFQL+LR LEK LLQ+LNE +G +L++D II LE LK+EAA+V +KVEETD+VMQEVE+VS +Y+ L+ +CS+IYFTLEA+NQ+HFLYQYSL LDI+ +VL N L +V + RL IT+ L + + LH F ++ L+G + + EFQHFLR +E +T K GLT +Q +++ RL +L F + +KV++ + W + +PE +VP +W +EK + I + ++ LL+IQA RPDRLLA + F++ VLGD+F LDLA+IV+ EV P+L+C+V GYD SG V DLA+EQ K +T I+IGSAEGF++A++ IN+A K+G+WVML+NVHLA WL+ LEKK+HS+Q H +FRLFLTMEI PK+PVNLLRAGR+ VFEPPPG+KAN+LRT SSI RM K P ER+RLYFLLAW +A++QERLRY PLG+SKKYEFGESD + A DT+DTW+D A GR N+ P+KIPW AL+TL+ IYGG+IDN FDQRLLN+FL +FT FD F L D +I P+ + + + WV LPD QTPSWLGLP++AE+VLL G ++G +LKMQ LED+++L K +RT D +PAWMR L+ + WLQ++P SV PL+RT+ENIKDP++R FEREV G +L VR+DL DV +VC+G KK TN R+++ DL KGI+P+ W RY +P +TVIQW+ DF++RIKQL IS AA G L++I V LG LF+ EAYITATRQ VAQ N W+LEEL L+V + + +D+ + I GL+L G+ + + L LST I ++ + +L+W++ +++ + V LP+YLN R+ ++FT+ F +T + ++FY+RGVAI Sbjct: 11 IERILGVRLQAGLRAWTQVLRGQMEDKADVDMDTEA---PQVSHKPGGEPKIKNVVHELRITNQVIYLNPPIEDCRYKLYQEMFAWKMVILSLPRIQSQRYQVGVHYELSEEEKFYRNALTRMPDGPAALEEAYNAVKENVSEVEQYVKVWLQYQCLWDMQPENIYNRLGEDLNKWQALLVQIRKARGTFDNAETKKEFGPVVIDYGKVQSKVNLKYDSWHKEVLSKFGQMLGNNMQDFHSQISKSRQELEQHSVDTASTSDAVTFITYVQALKRKIKQFEKQVDLFRNGQRLLEKQRFQFPPSWLYIDNIEGEWGAFSDIMKRKDTAIQQQVANLQMKIVQEDRAVENRTSDLLTDWEKTKPVAGNLRPEEALQSLTIYEGKFGRLKDDREKCAKAKEALELTDTGLLSGSEERVQVALEELQDLKGVWSELSKVWEQIDQMKEQPWVSVQPRKLRQSLDALLNQLKNFPARLRQYASYEYVQRLLKGYLKVNMLVIELKSEALKDRHWKQLMKRLHVNWVLSELTLGQIWDVDLQKNEMVVKDVLLVAQGEMALEEFLKQIREVWNSYELDLVNYQNKCRLIRGWDDLFNKVKEHINSVSAMKLSPYYKVFEEDALSWEDKLNRIMALFDVWIDVQRRWVYLEGIFTGSADIKHLLPVETQRFQSISTEFLALMKKVTKSPLVMDVLNIQGVQRSLERLADLLGKIQKALGEYLERERSSFPRFYFVGDEDLLEIIGNSKNVAKLQKHFKKMFAGVASILLNEDNTEVLGISSREGEEVLYKTPVSITEHPKINEWLTLVEKEMRVTLAKLLAESVTEVGAFNKATGIDLGAYINWIDRYQAQLVVLSAQIDWSENVEMALTTIAGKDDMAPLQDVLTKVEATLNVLADTVLMEQPPIRRKKLEHLITELVHQRDVTRTLIKNKIDNPKSFEWLSQMRFYFDPKQTDVLQQLSIQMANAKFNYGFEYLGVQEKLVQTPLTDRCYLTMTQALEARLGGSPFGPAGTGKTESVKALGHQLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLSAVSQQVQYIQVALREHSNPNRDRSTPVTTELLNKQVKVSAEMAIFITMNPGYAGRSNLPDNLKKLFRSLAMTKPDRQLIAQVMLYSQGFRTAETLAKKIVPFFKLCDEQLSSQSHYDFGLRALKSVLISAGNVKRERIQKIKREKCERGEDVDENEIAENLPEQEILIQSVCETMVPKLVAEDIPLLFSLLSDVFPGVQYMRGEMTALREELKKVCAEMYLTYGD-GDDVGSMWVEKVLQLYQITQINHGLMMVGPSGSGKTMAWRVLLKALERLEGVEGVAHIIDPKAISKDHLYGTLDPNTREWTDGLFTHVLRKIIDNVRGELQKRQWIIFDGDVDPEWVENLNSVLDDNKLLTLPNGERLSLPPNVRIMFEVQDLKYATLATVSRCGMVWFSEDVLSTDMIFNNFLARIRSIPLDEGEDE--AQRMRKGTEDEGEEAASPMLQIQRDVAAILQPYFTSTGLVIKALEHASKMEHIMDFTRLRCMGSLFSMMHQACRNIALYNNNHPDFPMPIDQLEKYIQKYLIYAVLWSFSGDGKLKMRAELGEYIRRITTVALPSAPNVP-IIDYEVCISGEWQSWQGKVPQIEVETHKVAAPDVVVPTLDTVRHEALLYTWLAEHKPLVLCGPPGSGKTMTLFSALRALPDMEVVGLNFSSATTPELLLKTFDHYCEYRRTPNGVVLAPVQLGKWLVLFCDEINLPDMDKYGTQRVISFIRQMVEHGGFYRTSDQTWVKLERIQFVGACNPPTDPGRKPLSHRFLRHVPVVYVDYPGPASLTQIYGTFNRAMLRLIPTLRTYAEPLTAAMVEFYTMSQERFTQDTQPHYIYSPREMTRWVRGIFEALRPLETLPVEGLIRIWAHEALRLFQDRLVEDEERRWTDENIDNVALKHFPNIDREKALNRPILYSNWLSKDYIPVEQEELRDYVKARLKVFYEEELDVPLVLFNEVLDHVLRIDRIFRQPQGHLLLIGVSGAGKTTLSRFVAWMNGLSVYQIKVHRKYTGEDFDEDLRTVLRRSGCKNEKIAFIMDESNVLDSGFLERMNTLLANGEVPGLFEGDEYATLMTQCKEGAQKEGLMLDTHEELYKWFTSQVIRNLHVVFTMNPSSEGLKDRAATSPALFNRCVLNWFGDWSTEALYQVGKEFTSKMDLEKPNYKVPDYMPTVYDK-LPQIPTHREAIVNGCVFVHQTLHQANNRLAKRGGRTMAITPRHYLDFINHYANLFNEKRSELEEQQMHLNVGLRKIKETVDQVEELRRDLRIKSQELEVKNAAANDKLKKMVKDQQEAEKKKVMSQEIQEAVYKQQEVIKDKQLRVKQDLDQVEPAVIEAQNAVKSIKKQHLVEVRSMANPPAAVKLALESICLLLGESTTDWKQIRSIIMRENFIPTIVNFSAEEISDAIREKMKKNYMSNPSYNYEQVNRASLACGPMVKWAIAQLNYADMLKRVEPLRNELQKLEDDAKDNKTKAEEVEQMIRDLEASIARYKEEYAVLISEAQAIKADLAAVEAKVNRSTALLKSLSAERERWEKTSETFKNQMSTIAGDCLLSAAFIAYAGYFDQQMRQNLFTTWSHHLQQANIQFRTDIARTEYLSNADERLRWQANSLPADDLCTENAIMLKRFNRYPLIIDPSGQATEFIMNEYKDRKITRTSFLDDAFRKNLESALRFGNPLLVQDVESYDPILNPVLNREVRRTGGRVLITLGDQDIDLSPSFVIFLSTRDPTVEFPPDLCSRVTFVNFTVTRSSLQSQCLNEVLKAERPDVDEKRSDLLKLQGEFQLRLRQLEKSLLQALNEVKGRILDDDTIITTLENLKKEAAEVTRKVEETDIVMQEVENVSQQYLSLSTACSSIYFTLEALNQMHFLYQYSLHFFLDIYHTVLYENANLKSVSDHTQRLA-ITRGLLNICFP------LH-----FFSV-----LRGVSSEPPYDPEFQHFLRGKEIVLTGMTLPKVK--GLT--TEQCEAMVRLSRLPTFKDLVDKVQADEQFFMWLESNSPELSVPYIWA------EEKTTPIGQAVHQLLLIQAFRPDRLLAMSTIFVSRVLGDSFMSITEQPLDLANIVDSEVKPGTPVLMCSVPGYDASGLVRDLAAEQNKHITSISIGSAEGFNKADRDINTAVKSGRWVMLENVHLAPGWLMQLEKKLHSMQPHASFRLFLTMEINPKVPVNLLRAGRIFVFEPPPGVKANMLRTFSSIPVARMCKAPNERARLYFLLAWFHAVIQERLRYAPLGWSKKYEFGESDLRSACDTVDTWLDDTAKGRQNISPDKIPWAALKTLMAQSIYGGRIDNEFDQRLLNTFLERIFTTGSFDSEFKLALKVDGHKDIKMPDGIRREEFMHWVEMLPDTQTPSWLGLPSNAERVLLATQGTDMMGKLLKMQM-LEDEDDLAYETEKKQRTASSSDAQPAWMRTLHTTACNWLQLIPLSVNPLKRTVENIKDPLFRFFEREVKMGARMLQDVRQDLTDVVQVCQGKKKQTNDLRTLINDLVKGILPRSWCRYTVPTSMTVIQWVADFSERIKQLQQISQGAASGGAKELKNIHVNLGSLFVPEAYITATRQYVAQANSWSLEELGLEVNVTSAQGAALDACSFGIKGLKLQGATCTNNK-LSLSTSISTELPLTQLRWVKQVNAEK------GNMVTLPVYLNFTRTDLIFTVDFDIATKEDPHNFYERGVAI 3725
BLAST of Cytoplasmic dynein 1 heavy chain 1 vs. Ensembl Cavefish
Match: dnah2 (dynein, axonemal, heavy chain 2 [Source:ZFIN;Acc:ZDB-GENE-130530-910]) HSP 1 Score: 1427.92 bits (3695), Expect = 0.000e+0 Identity = 1026/3694 (27.77%), Postives = 1815/3694 (49.13%), Query Frame = 3 Query: 3255 YVKTWTNYQSLWDLQGDQLFSLIADDNTVWMNVLEEIKSMRKHFDVAE-TQKEFGPLVIAF-----GKVQSKVSMKYDNWHKEVLTKFGQNMGKMMTTLYNEVQR-ARNELEQQSIDSGGTNESVNFITYTQNIKRKMNTWEKQAEACRAGQNILCRDRFQFPNDWLDS-ENIQGEWSAFKEIMRRKQETISSQVASLQMKITEEDKIVESKTTEVLGNWEKDKPIAGDLTPEEAVNIIQILEGKFNRLKEERENVQKAKEALELTEIGVKPISEEKVTNALSELHDLKNVWNELKSIWEKIRD-MKETPWLSVQPRKLRQDIENLTAQLKELPNSFK--QYASFEHVRTLLKMYMKVNASIVELKSEAIKERHWRMLMRKLNVSWSLN--ELQLGKVWDIDLVKNEEIIREVLAIAQGEKALEEYLRQITEVWKNYVLELTNYQSKSKIIKGWDDLFNKVKEHINNVTSMKASPYFKQFEEEATAWEDRLNKINALFDVWIDVQRRWIYLDGIFAGSADIKVLLPVESQRFQSVSTEFLGLMKKVQKSPLVTDVLNIANVQRQLERLADL---LGKIQKSLGEYLERQRSSFPRFYFVGDEDLLEIIGNSXXXXXXXXXXXXMFAGVHSIILSE---DEKVILGMMSKEGEELRFISPVSIIEHPRINDWLTAMEKEMRVSLAKYLN---VAVKEISGWRTESNIDKDKFMVWLDKYQAQIVVLAAQITWSEAVEASLASG------VSLESTMTVVHSTLNMLADTVLYEQPPVRRRKLEHLIIEYVHQRDVLRALHNDGVSSNKNFDWMSQMRFYFDPKQTDPLHQLSIHVANAKFHYGFEYLGVCDRLVQTPLTDRCYLTMTQALEARLGGSPFGPAGTGKTESVKSLGNQLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLSAVSQQIQGIQEALRELMVSKKDSINVELLGKQVHVNPDMAIFITMNPGYAGRSNLPDNLKKLFRSLAMTQPDRQLIAQVMLYSQGFRTAEVLAGKVVPFFKLCDEQLSPQSHYDFGLRALKSVLVSAGNVKRDRIKQEKEKIVARGEEINETAIAEQLPEQEILIQSVMETMVPKLIADDIPLLYSLLTDVFPGVEYRQAEMKRLREELRKVSENKFLVYSDEPNTAGYLWVEKVLQLYQITTIHHGLMMVGPSGSGKTMACRVLLQALENI--DGIEGV----AHIIDPKSISKDSLYGYMDPNTREWTDGLFTHILRRIIDSVRGESNKRQWIVFDGDVDPEWVENLNSVLDDNKLLTLPNGERLAIPPNVRIMFEVQDLKYATLATVSRCGMVWFSEEVLTTGMILTHFLNELKKVQVMEGEEDFSVNQGDTGADADSKISSSPIIQLQTQVSSILAPFFTEDGLIAKCLDYSTTLEHIMDFTRLRALTSLFSMIKQSIRNMIEYNQSHSDFPLNNEQIENYVAKSLISSVVWSMSGDSKLKVREQLSQYIKNISTVDLPTVGGIKNIIDFEVNIQG-TWVAWSNKVPQIEVETHKITATDVVVPTMDTVRHEALLYTWLAEHRPVLLCGPPGSGKTMTLFSALRCLPDME--VVGLNFSSATTPELMLKTFDQYCEYRKTPNGIVLAPQQLNKWLIFFCDEINLPDMDKYGTQRVISFLRQMVEHHGFYRITDMQWVSFERIQFVGACNPPTDPGRKPLSHRFLRHVPVVYVDYPGETSLKQIYSTF-NRAMLRMLPSLRGYADTLTNAMVEFFLKTQERF-THDMQPHYIYSPREMTRWVRGIHEALKPLESLSVEGLVRIWAHEALRLFQDRLVEEDERHWTDDNINEVALK-------HFPNI--NKEEA-----LKRPILYSNWLSKDYSAVTQEELRDYVKARLKVFYEEELDVP--LVLFNQVLDHVLRIDRVFRQPQGHLLLIGVSGAGKTTLSRFVSWINGLSVFQVKVHNKYTAEDFDEDLRNVLRRSGCKGEKITFIMDESNVMDSSFLERMNTLLANGEVPGLFEGDELTTLMTQCKEGAIREGLMIDSQEELYKWFTQQICRNLHVVFTMNPSADGLKDKASTSPALFNRCVLNWFGDWSLEAYFQVGKEFTNRL---DLERTDYKVPDTLPCIAEGLLPQNPIYRDVVVNALVFVHQTMHQANVRVQKRGGRTAAITPRHYLDLIAHYMKLSAEKRADLEEQQLHLNNGLKKIEQTVDQVEVMQRSLTKKRQELENMNEAANAKLKQMVQDQQEAEQKKTTGQALKEELAKQEQFVNEKQKTVKQELDQVEPTVNEAKQAVQNIRKKDIQEIKAMKNPPNAVKMAVESICLLLGEKTTDWQSILKVIIKDTFVTSILNFNTDDVSDNTRETMKKKYLSNPDYNFEKVNKASNACGPMVKWVLAQISYADILKRVEPLRNELTELSDAAEQNRKKSQETEDLIAQLEKSIAKYTEEYATLISQAQTIKSDLASVESKVGRSVALLGSLSSERTRWDSGSETFKAQMATINGDCLLSSAFMAYGGYFDQHMRTSLF-NTWCHHLSEADILFRSDLARVEYLSNPDDRLRWQANSLPADDLCVENAIILRRYNRYPLIIDPSGQATTFLLNEYKEKKITKTSFLDDSFRKTLESALRFGTPLLVQDV-ESYDPILNPVLNREVRRTGGRTLITLGDQDIDLSPTFTIFLSTRDPSVEFAPDICSRVTFVNFTVTRSSLQNQCLNAVLKIERPDIDQKRSDLLKAQGEFQLKLRHLEKDLLQSLNEAQGNLLENDKIIARLETLKREAADVAKKVEETDVVMQEVESVSTEYVPLAQSCSNIYFTLEAMNQIHFLYQYSLQLMLDIFSSVLINNPELTNVKAASDRLKIITKNLFQ--VTYNRLARGMLHEDQITFATILARIFLKGSTPIGFLENEFQHFLRSQEATITSSDSNKQDNLGLT-LHQDQIDSVKRLKKLKVFAKIEEKV-KSTKDIKNWTLTVTPE-SNVPELWVDDNNYNDEKLSKIAKGMYNLLIIQAIRPDRLLASTQKFIASVLGDTFTESVRGTLDLASIVEVEVTACVPILLCAVQGYDPSGRVEDL--ASEQGKQLTGIAIGSAEGFSQAEKAINSAAKTGKWVMLKNVHLATSWLVSLEKKIHSLQ---AHPNFRLFLTMEITPKLPVNLLRAGRVLVFEPPPGIKANLLRTLSSINNQRMSK--EPVERSRLYFLLAWLNAIVQERLRYVPLGYSKKYEFGESDFKCALDTIDTWVDGAAMGRTNLPPEKIPWVALQTLLGSCIYGGKIDNAFDQRLLNSFLGYLFTEKCFDHNFALVSDADDGSNIAFPESTKHTDILQWVHKLPDLQTPSWLGLPNSAEKVLLTNLGQSLIGNILKMQQSLEDDEELVVGQSKTKRTIEVGDGRPAWMRQL--YQSTQTWLQILPKSVTPLQRTIENIKDPMYRCFEREVNSGCNLLASVRKDLEDVAEVCKGAKKPTNHHRSMMADLAKGIIPKMWIRYAIPPGLTVIQWIQDFADRIKQLLHISDTAAKSGVIALRSIQVWLGGLFMAEAYITATRQSVAQNNKWALEELFLDVELGEGKVDSNTCV--------ITGLRLMG-------SEIVDPRTLKLSTLIYKDIDICRLKWIRVEKSQQLEGSSAKDKVCLPIYL------NAARSTVLFTLYFSTTDSSYDFY-KRGVAI 14048 Y+KTW ++ +W++ D N + +I ++ +VA QKE L + F ++ + + W KF Q + M +T E+ ++ + S E V + + ++ +N E Q IL + + D E + GEW F++++ + + + + + K + ++ P +++ E A+ I +L + LKEE ++ + TE +P S++ + N ++ L VW E+ W+ D K + S+Q + + + L +L K Q+ E + ++ + + I++L+ A+++RHW + +++ S+ N E L K+ + L ++ E I E+ A+ E ++E+ L I + W+ L++ Y+ K G +++F ++++ +++MKAS + + FE+E WE L+ + + ++ + VQR+W+YL+ IF G DI+ LP ES F +++ + +M ++ K + L + LE+L+++ L +IQKSL YLE +R FPRFYF+ ++DLLEI+G S++ +Q H KK F + S+ +++ ++ GM S +GE + F PV ++E P + WL +E+ MR +L L A+K+++G R DK W+ + Q+++ A+QI W+ V L +G +L+S S L+ +D + + R K+ L+ VH RDV+ L G FDW+ Q+R Y++ D + I N F YG+EYLG RLV TPLTDRCY+T+T AL GGSP GPAGTGKTE+VK LG LG +V+V NC + D+++MGR++ GL Q GAWGCFDEFNR+ +LS V+QQI I AL + N G+ + + IFITMNPGYAGR+ LPDNLK +FR ++M PD LIA++ L+ +GF +VLA KV + L +QLS Q HYDFGLRAL S+L AG +R R + ++EIL+ S+ + + KL + D+PL ++ D+FP VE + +L+E + + L + P T V KV+QLY+ H M+VG +GS K++ ++L +AL + G G + ++PK++S LYG D +T EWTDG+ + ++R + E +WIVFDG VD W+E++NSV+DDNK+LTL NGER+A+P V ++FEV+DL A+ ATVSRCGMV+ L + ++++ +K++V + F D I + I + L P +G+I+ C Y + S N + P +NE V I S++WS+ R+++ +++ + T I ++ V+ + TW ++ +K+P+ ++VPT+DTVR+ L+ + + PVLL GP G+GKT S L+ L + ++ +N SS TT + + E R + + K ++ F D++N+P +D +G+Q + LR +++ GF+ M+ F + + PP GR +S R ++ + +P E+ +K I+ T N+ + ++ LT A +E + RF + HY+++ R++++ +G+ + + + + + R+W HE R+F DRLV++ + T+ + +A K + NI NK++ LK P +Y + L D+ A L+ +++++L+ + VP LVLF ++HV R+ RV QP+G++LL+G+ G+G+ +LSR ++I VFQV+V +Y ++F ED++ + R +G + F+ +++ ++D SFLE +N +L++GEVP L++ DE + + + A +E ++ ++ + ++ + +++ NLH+V M+P + +++ PAL N L+WF +W +A +V + + + L ++E+ KV V +HQ++ Q + R++ R +TP +YL+L++ Y KL AEKRA+L EQ L NGL KI+ T +VE M L ++++ + + L +VQ ++EA++++ A E++ +E + +++LD+ P + EA +A++++ KKD+ EIK+ PP V+ ++++ +L G + T W + + + F+ +++F+ D++SD + + + Y + PD+ E + + S A + WV A Y I + VEP R L + + E E+ ++E+ + + +Y ++Q + ++ +E K+ R+ L+ L+ ER RW+ E+ + M + GDCLL++AF++Y G F + R L N W + ++ +LS P W LP+D EN +I+ R NR+PL++DP GQA ++ N ++ + F + LE+A++FG+P+L+Q+V E DP L P+LN+ GGR L+ LGD++++ +P F +++T+ + + P+I ++ T VNF V L+ Q L V++ ERP++++++ L+ + KL+ LE ++L+ LNEA G+LL++ +++ L+T K A +V+ ++E ++ ++++ Y P AQ S ++F L M +I +YQ+SL +D+F+ + + ++ +II N + Y RG+ ++ F+ + L+ + + +E+ FLR + + DN + L D++ L KL F + K KD W + PE + +P W + + +LI++++R DR+ FI + LG F E LD+ +++E + T P++ G DP+G + L AS G +++G + A + I K G WV L N HL+ SW+ L+K + LQ +HP+FRL+L+ P+ P+ +L+AG + EPP G+K+N+ R + + S+ PV +L F L + ++I+ ER +++ LG++ Y F +SDF+ + + + ++D E+IPW AL+ L+ YGG + + +D+RLL +++ F E + F +S P +++ +LP ++ P G +A+ + ++L +L +Q + G S+ + +E+ + +L Y+STQ LQ P P+ +E+ LL ++R L ++ + KG ++ M + +P +W + A P + W +D R++Q H ++TA + WL G ++TA QS A+ + +++ L E VD N + I GL L G S +V+ ++L +C + I + AK+ P Y A R + + + + SY+ + KRG A+ Sbjct: 946 YLKTWDKHREIWEINKDSFIRRYQHLNPPVSSFDSDIA---RYSEVANNVQKEETVLSVQFVLLDCSPLKFSLVQHCNEWQ----GKFTQLLSLMASTRLKELHSFLQDNAHRLSQPPQTLVELVEGLKLLETLQGDLNKIESQIPPIHEQFAILEKYEVSVEREVQDLLEALNGEWQGFQQVVIDSDIMLKKHKDKFKSGLFFSAEEFKKKMQTTMQDFNSTGPFGSNVSSEAALEQISVLRAQLESLKEEEGTIRHGLSIFK-TE---QPTSKD-MQNLEKDIDYLLQVW-EISQQWDTHWDEWKAGQFASLQTENMESTAQTMYKNLNKLSRELKDKQWEIVEFSKNRIEQFKRTIPMILDLRDPAMRDRHWNQIKQEMQRSFDHNSAEFTLEKIVALGLEQHAERICEISGAARKELSIEQSLEGIAKTWEETSLDIAPYKDK-----GTEEVFQALEDNQVTLSTMKASRFVRAFEKEVDRWERCLSLVLEVIEMILTVQRQWMYLEIIFLGE-DIRKQLPHESTEFDDINSSWKTIMDRLNKD---NNALRGTHHPGLLEKLSEMNSKLEEIQKSLDMYLETKRQIFPRFYFLSNDDLLEILGQSRNPDAVQPHLKKCFDNIKSLRINKVRNNKSEAAGMFSADGEFVEFTHPV-LLEGP-VEAWLCDVERTMRWTLKDTLRNCRTALKKMTGKR-------DK---WVKDWPGQMLITASQIQWTTDVTKCLITGKESADKSALKSMKKKQVSMLHRYSDAIRGNLSKILRLKIVALVTVEVHARDVIDKLAKAGCCDVNAFDWLCQLRLYWEKDVDDCI----IRQTNTHFQYGYEYLGNSGRLVITPLTDRCYMTLTTALHLHRGGSPKGPAGTGKTETVKDLGKGLGMYVIVVNCSDGLDYKSMGRMYSGLAQTGAWGCFDEFNRINIEVLSVVAQQILSILSALSAGLT------NFIFEGRDICLVSSCGIFITMNPGYAGRTELPDNLKSMFRPISMVVPDSTLIAEITLFGEGFNNCKVLAKKVFTLYCLAVQQLSKQDHYDFGLRALTSLLRYAGKKRRVR---------------------PDIADEEILLMSMKDMNIAKLTSTDLPLFNGIIQDLFPAVETPTIDYGKLKETIEEELHQSGLQVT--PFT-----VTKVIQLYETKNSRHSSMIVGKTGSSKSVTWQILQKALSAMHRKGEPGFNLVHEYPLNPKAVSLGELYGEYDLSTNEWTDGVLSSLMRI---ACADEKPDEKWIVFDGPVDTLWIESMNSVMDDNKVLTLINGERIAMPEQVSLLFEVEDLAVASPATVSRCGMVYNDYSDLGWKPYVQSWIDKRQKMEVDHLKRLF-----------DRYIKKT--ISFKRTHCKELVPITELNGVISLCRLYDSL---------------------ASPENGVN--------PADNENYGRMVELWFIFSLIWSICASVDEDGRKKIDNFLREMEG----TFPNKDTIYEYYVDTKNKTWASFEDKLPKGWRYPSNAPFYKIMVPTVDTVRYHFLVNSLVCGQYPVLLTGPVGTGKTSVAQSVLQGLDPAKWTMLTINMSSQTTSNNVQAIIESRVEKRTKGTYVPVG----GKKMLAFLDDLNMPAVDDFGSQPPLELLRLWIDY-GFWYDRQMKMDMF----LLASMGPPGG-GRTHISGRLQSRFNLINMTFPAESQIKHIFGTMINQKLQEFQEEVKPIGSILTQATLELYYAISARFLPTPAKIHYLFNLRDISKVFQGLLRSHRDFHD-TKQSITRLWIHECFRVFSDRLVDQAD---TEAFVALLAEKLGSLFDLTYHNICPNKQQPIFGDFLKEPHVYEDLL--DFKA-----LKGFMESQLEDYNLTPGVVPMSLVLFRDAIEHVTRVVRVISQPRGNMLLVGIGGSGRQSLSRLAAYICEYMVFQVEVTKQYRKQEFREDIKKLYRLTGVDNKPTVFLFNDTQIIDESFLEDINNILSSGEVPNLYKSDEFEEVQSALSDSARKENVL-ETADAMFNYLIERVRNNLHIVLCMSPVGEPFRNRIRQYPALVNCTTLDWFSEWPQDALLEVAERYLDGLILGNVEKIQTKV----------------------ARIFVTMHQSVAQFSQRMKLELKRHNYVTPTNYLELVSGYKKLLAEKRAELGEQVSKLRNGLFKIDDTRSKVEAMSVELEDAKKKVAEIQKQCEEYLVVIVQQKREADEQQMAVSAHSEKIGAEEIKCKAMAENAQRDLDEALPALEEAMKALESLNKKDMTEIKSYGRPPALVETVMQAVMILRGCEPT-WAEAKRQLGESNFIKQLVHFDKDNISDRVLKKIGQ-YCTQPDFQPEIIGRVSLAAKSLCMWVRAMEVYGRIYRVVEPKRARLHGAMTQLAEKQAALAEAENKRREVEEKLKQLKNQYDEKLNQKEDLRKKSEDMELKLDRAGKLVSGLAGERVRWEQTVESLEKDMGYLVGDCLLAAAFLSYMGPFLSNYREELLTNIWMKQFRDLEVPCSPGFNFATFLSKPTAVRDWNIQGLPSDAFSTENGVIVTRGNRWPLMVDPQGQALKWIKNMESKRGLKVIDLQMPDFLRILENAVQFGSPVLLQNVQEELDPSLAPILNKSFTHIGGRVLLKLGDKEVEYNPDFQFYITTKLSNPHYTPEISTKTTIVNFAVKEQGLEAQLLGIVVRRERPELEEQKDSLVINIASGKRKLQELEDEILRLLNEATGSLLDDVQLVNTLQTSKITATEVSDQLETSEQTEIKIDTAREAYRPCAQRASILFFVLNDMGRIDPMYQFSLDAYIDLFNLSIEKSQRSHKLEE-----RIINLNDYHTYAVYRYTCRGLFERHKLLFSFHMCAKILEVAGKLNM--DEYSFFLR---GGLVLDKEGQMDNPCTSWLADSNWDNITELDKLANFHGLMSSFEKYPKDWHQWYTSSEPENAPLPGEW-----------ETVCNELQKMLIVRSLRQDRVSFCVNSFIINNLGSRFVEP--PVLDMKAVME-DSTTKTPLIFVLSPGVDPTGALVQLAEASGMGPSFHALSLGQGQA-PIATRMIKEGVKNGHWVFLANCHLSLSWMPQLDKLVEQLQVEDSHPDFRLWLSSSPHPEFPIAILQAGIKMTTEPPKGVKSNMKRLYQLVTESQFSRCSRPVVYRKLLFSLCFFHSILLERKKFLQLGWNIVYSFNDSDFEVSENLMSLYLDEY---------EEIPWDALKYLIAGVNYGGHVTDDWDRRLLTTYINDYFCEGAVNTPFFKLSSL---PTYYIPRDGSQDTYREYIRQLPPVEHPEVFGQHPNADIASQISETRTLFDTLLSLQPQVTSTTATGAGPSREDKVLEISADVRQKVPELVDYESTQKLLQDDP--------------SPLNVVLLQEIQRYNALLHTIRTSLTELEKGIKGLVVMSSSLEEMFQCIHDARVPPLWEK-AYPSLKPLASWTRDLCQRVEQFAHWAETAHP-------PVLFWLSGFTFPTGFLTAVLQSSARQHNVSVDT--LSWEFIVSTVDDNNLLFPPKDGVFIRGLYLEGAGWDKKNSCLVEAEPMQL---------VCPMPTIHFRPVEN-RKKVAKNMYSCPCYYFPVRSGGAGRPSFVVGVDLKSGAVSYEHWIKRGTAL 4401
BLAST of Cytoplasmic dynein 1 heavy chain 1 vs. Ensembl Cavefish
Match: ENSAMXT00000016172.2 (pep primary_assembly:Astyanax_mexicanus-2.0:4:1379218:1548247:-1 gene:ENSAMXG00000015711.2 transcript:ENSAMXT00000016172.2 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 1331.24 bits (3444), Expect = 0.000e+0 Identity = 968/3517 (27.52%), Postives = 1731/3517 (49.22%), Query Frame = 3 Query: 3804 SSQVASLQMKITEEDKIVESKTTEVLGNWEKDKPIAGDLTPEEAVNIIQILEGKFNRLKEERENVQKAKEALELTEIGVKPISEEKVTNALSELHDLKNVWNELKSIWEKIRDMKETPWLSVQPRKLRQDIENLTAQLKELPNSFKQYASFEHVRTLLKMYMKVNASIVELKSEAIKERHWRMLMRKLNVSWSLNELQLGKVWDIDLVKN-EEIIREVLAIAQGEKALEEYLRQITEVWKNYVLELTNYQSKS-KIIKGWDDLFNKVKEHINNVTSMKASPYFKQFEEEATAWEDRLNKINALFDVWIDVQRRWIYLDGIFAGSADIKVLLPVESQRFQSVSTEFLGLMKKVQKSPLVTDVLNIANVQRQLERLADLLGKIQKSLGEYLERQRSSFPRFYFVGDEDLLEIIGNSXXXXXXXXXXXXMFAGVHSIILSED-----EKVILGMMSKEGEELRFISPVSIIEHPRINDWLTAMEKEMRVSLAKYLNVAVKEISGWRTESNIDKDKFMVWLDKYQAQIVVLAAQITWSEAVEASLAS-GVSLESTMTVVH----STLNMLADTVLYEQPPVRRRKLEHLIIEYVHQRDVLRALHNDGVSSNKNFDWMSQMRFYFDPKQTDPLHQLSIHVANAKFHYGFEYLGVCDRLVQTPLTDRCYLTMTQALEARLGGSPFGPAGTGKTESVKSLGNQLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLSAVSQQIQGIQEALRELMVSKKDSINVELLGKQVHVNPDMAIFITMNPGYAGRSNLPDNLKKLFRSLAMTQPDRQLIAQVMLYSQGFRTAEVLAGKVVPFFKLCDEQLSPQSHYDFGLRALKSVLVSAGNVKRDRIKQEKEKIVARGEEINETAIAEQLPEQEILIQSVMETMVPKLIADDIPLLYSLLTDVFPGVEY-RQAEM---KRLRE---ELRKVSENKFLVYSDEPNTAGYLWVEKVLQLYQITTIHHGLMMVGPSGSGKTMACRVLLQALENIDGIEGVAHIIDPKSISKDSLYGYMDPNTREWTDGLFTHILRRIIDSVRGESNKRQWIVFDGDVDPEWVENLNSVLDDNKLLTLPNGERLAIPPNVRIMFEVQDLKYATLATVSRCGMVWFSEEVLTTGMILTHFLNELKKVQVMEGEEDFSVNQGDTGAD--ADSKISSSPIIQLQTQVSSILAPFFTEDGLIAKCLDYSTTLEHIMDFTRLRALTSLFSMIKQSIRNMIEY------NQSHSDFPLNNEQIENYVAKSLISSVVWSMSG----DSKLKVREQLSQY-IKNISTVDLPTVGGIKNIIDFEVNIQ-GTWVAWSNKVPQIEVETHKITATDVVVPTMDTVRHEALLYTWLAEHRPVLLCGPPGSGKTMTLFSALRCL-PDMEVV-GLNFSSATTPELMLKTFDQYCEYRKTPNGIVLAPQQLNKWLIFFCDEINLPDMDKYGTQRVISFLRQMVEHHGFYRITDMQWVSFERIQFVGACNPPTDPGRKPLSHRFLRHVPVVYVDYPGETSLKQIYSTFNRAMLRMLPSLRGYADTLTNA---MVEFFLKTQERFTHDMQP-----HYIYSPREMTRWVRGI----HEALKPLESLSVEGLVRIWAHEALRLFQDRLVEEDERHWTDDNINEVALKHFPNINKEEALKRPILYSNWL-------SKDYSAV-TQEELRDYVKARLKVFYEEELDVPLVLFNQVLDHVLRIDRVFRQPQGHLLLIGVSGAGKTTLSRFVSWINGLSVFQVKVHNKYTAEDFDEDLRNVLRRSGCKGEKITFIMDESNVMDSSFLERMNTLLANGEVPGLFEGDELTTLMTQCKEGAIREGLMIDSQEELYKWFTQQICRNLHVVFTMNPSADGLKDKASTSPALFNRCVLNWFGDWSLEAYFQVGKEFTNRLDLERTDYKVPDTLPCIAEGLLPQNPIYRDVVVNALVFVHQTMHQANVRVQKRGGRTAAITPRHYLDLIAHYMKLSAEKRADLEEQQLHLNNGLKKIEQTVDQVEVMQRSLTKKRQELENMNEAANAKLKQMVQDQQEAEQKKTTGQALKEELAKQEQFVNEKQKTVKQELDQVEPTVNEAKQAVQNIRKKDIQEIKAMKNPPNAVKMAVESICLLLGE-----KTTDWQSILKVIIK-DTFVTSILNFNTDDVSDNTRETMKKKYLSNPDYNFEKVNKASNACGPMVKWVLAQISYADILKRVEPLRNELTELSDAAEQNRKKSQETEDLIAQLEKSIAKYTEEYATLISQAQTIKSDLASVESKVGRSVALLGSLSSERTRWDSGSETFKAQMATINGDCLLSSAFMAYGGYFDQHMRTSLF-NTWCHHLSE--ADILFRSDLARVEYLSNPDDRLRWQANSLPADDLCVENAIILRRYNRYPLIIDPSGQATTFLLNEYKEK----KITKTSFLDDSFRKTLESALRFGTPLLVQDVE-SYDPILNPVLNREVRRTGGRTLITLGDQDIDLSPTFTIFLSTRDPSVEFAPDICSRVTFVNFTVTRSSLQNQCLNAVLKIERPDIDQKRSDLLKAQGEFQLKLRHLEKDLLQSLNEAQGNLLENDKIIARLETLKREAADVAKKVEETDVVMQEVESVSTEYVPLAQSCSNIYFTLEAMNQIHFLYQYSLQLMLDIF-SSVLINNPELTNVKAASDRLKIITKNLFQVTYNRLARGMLHEDQITFATILARIFLKGSTPIGFLENEFQHFLRSQEATITSSDSNKQDNLGLTLHQDQIDSVKRLKKLKVFAKIEEKVKST-KDIKNWTLTVTPES-NVPELWVDDNNYNDEKLSKIAKGMYNLLIIQAIRPDRLLASTQKFIASVLGDTFTESVRGTLDLASIVEVEVTACVPILLCAVQGYDPSGRVEDLASEQG-----KQLTGIAIGSAEGFSQAEKAINSAAKTGKWVMLKNVHLATSWLVSLEKKI--HSLQAHPNFRLFLTMEITPK-----LPVNLLRAGRVLVFEPPPGIKANLLRTLSSINNQ--RMSKEPVERSRLYFLLAWLNAIVQERLRYVPLGYSKKYEFGESDFKCALDTIDTWVDGAAMGRTNLPPEKIPWVALQTLLGSCIYGGKIDNAFDQRLLNSFLGYLFTEKCFDHNFALVSDADDGSNIAFPESTKHTDILQWVHKLPDLQTPSWLGLPNSAEKVLLTNLGQSLIGNILKMQQSLEDDEELVVGQSKTKRTIEVGDGRPAWMRQLYQSTQTWLQILPK--SVTPLQRTIENIKDPMYRCFEREVNSGCNLLASVRKDLEDVAEVCKGAKKPTNHHRSMMADLAKGIIPKMWIRYAIPPGLTVIQWIQDFADRIKQLLHISDTAAKSGVIALRSIQVWLGGLFMAEAYITATRQSVAQNNKWALEELFLDVE-LGEGKVDSNT-----CVITGLRLMGSE-------IVDPRTLKLSTLIYKDIDICRLKWIRVEKSQQLEGSSAKDKVCLPIYLNAARS-TVLFTLYFSTTDSSYDFYKRGVAI 14048 +S+VA+L+ K D + + K E ++ K+ P D+ VN ++L+ +++E + K E+ L E+ + + K E+ LK +W+ + + + + TPW + ++ + + + +L+ L + + +F + + +K + +I EL++ AI+ RHW+ LM V +S++E + + E+ +R ++ A E +E+ L ++ W ++ S ++K +DL ++++ + ++ +S + F EE ++W+ RL+ +++ +W +VQR W +L+ IF GS DI+ LP +S+RF+ + T+F L K+P V + N + +LE + L +K+L EYL+ +R +FPRFYF+ DLL+I+ N D ++Q+H K+F + D K +GM SKE E + F P ++ WL + MR ++ + AV E WL Y AQ+ + QI W+ V + + E+ M + S LN L ++ + P R+K+ + VH RDV+ + V +++ F W+SQ+R +D ++ H + ++ +A+F Y +EYLG RLV TPLTDRCY+T+TQ+L + G+P GPAGTGKTE+ K LG LG V VFNC E D+++ G I+ GL Q GAWGCFDEFNR+ +LS V+ Q++ IQ+A+R+ KK N +G+++++ P + IFITMNPGYAGR+ LP+NLK LFR AM PD +LI ++ML ++GF A +LA K + ++LC E LS Q HYD+GLRA+KSVLV AG++KR ++ PE ++L++++ + VPK++ DD+P+ L+ D+FP ++ R+ ++ K +RE +L+ +E+ F++ KV+QL ++ + H + +VG +G+GK+ + L + +N+ V ++PK+++ D L+G ++P TREW DGLF++I+R + + +WIV DGD+DP W+E+LN+V+DDNK+LTL + ER+ + P +R++FE+ L+ AT ATVSR G+++ +NQ D G + S I ++Q++ +++ F D + CLD T + + +QS+ M+ + H+ + E E Y + + +W+ G D + R + S++ + T+ P+ G + D+ ++ + + WS VP+ E++ +I +V T +T+R + L RP++L G G+GK++ + L L PD + + F+ TT ++ ++ E + N P +K LI+F D++N+P++D YGT + + +RQ ++++ +Y + +Q +Q+V NP + G ++ R RH V + +PG +L IY + +L S G++ + + +V+ L +R T P HYI++ R+++ +G+ E +K + + LV+++ HE+ R+++D++VE+ + D +E+ K + ++ EEAL+ + + + Y V + E L + L + E + LVLF + H+ RI+R+ P+G+ LL+GV G+GK +L+R ++I+ L VFQ+ + Y D DL + ++G K F+M ++ V D FL +N LLA+GE+P L+ DE+ ++ + +GL+ DS+E +K+F +++ R L V +P L+ ++ PA+ N V++WF +W EA V F L+ ++ P+ +D V + +VH ++++ + R TP+ +L+ I Y L A KR DL + L NGL+K+ T QV+ ++ L + +L+ NE A+ ++ + + ++ ++K +E++A V KQK +++L + EP + A++A+ + K ++ E+K+ +P AV ++ +L+ K W++ ++ K D F+ S++NFN +++ +N + ++ YL +P++ E V SNA + WV+ + + ++ VEP R L + + ++K + I L +++AK T ++ + + + + + + L+G L+SE RW FK Q T+ GD LL +AF++Y GYF + R L NTW +LS+ I L + L + D WQ LPAD + ENA IL R+PL++DP Q ++ N+Y + +I + +LD ++E AL G +L++++E + DP+L P+L +E + G I +GD++ + +P F + L T+ + + P++ ++ T +NFTVTR L++Q L AV+ +ERPD+++ +S+L K Q F++ L+ LE +LL L+ A GN L + +++ LE KR AA++ +KV+E V ++ Y P A S +YF + +N+IH +YQ+SL+ +F +VL P+ + + + IT ++FQ T RG+ D++T+ LA L + I E +F Q + D + G +K L + F ++ ++S+ K K + PE P+ W K + L +++A+RPDR+ + + F+ LG + + ++D A E E A P+ G DP VE G + +++G + AE+A++ AA+ G WV+L+N+HL WL +LEKK+ H + NFR+F++ E + +P +L + EPP G+ ANL + L + N M E + F L + +A+V ER ++ P G+++ Y F D +++ + +++ + K+P+ L+ L G +YGG I + +D+RL ++L + + L P + + Q++ ++P GL +AE LT + L +L+MQ + G+ G R ++ + + T L+ LP+ ++ L +E + P +E L +++ L+++ KG TN ++ + +P W + A P + W D +RI++L S VWL G F ++++TA QS A+ N+W L+++ L + L + + D ++ + GL + G+ IVD R +L+ I + +K + V+K + ++ P+Y R T ++T T ++ + GVA+ Sbjct: 1056 ASEVANLRRKCATFD-VEQFKFRE---HFRKNGPFRFDI-----VNPYEMLDTTHKQIQEMESIMAKLIESAGLFEVNIPDYKQLK--QCRKEVSILKELWDVVSVVRFNLEAWRTTPWREINVEEMELECKRFSKELRLLDKEARAWDAFCGLDSTVKNTLTSLRAIAELQNPAIRPRHWQQLMTATGVRFSMDEDTTLTDLLNLNLHHFEDEVRAIVDRAVKEMGMEKVLTELDATWTAMEFGYESHPRTSVPLLKSDEDLVETLEDNQVQLQNLMSSKHVAFFLEEVSSWQKRLSVADSVISIWFEVQRTWSHLESIFIGSEDIRSQLPEDSKRFEGIDTDFKELAYDAHKTPNVVEATNKPGLYSRLEDIQGRLALCEKALAEYLDTKRLAFPRFYFISSADLLDILSNGTDPHQVQRHLSKLFDNTAKMKFETDADGKPSKTGIGMFSKEEEYVPFNEPCDCTG--QVEMWLNRVLDTMRATVRHEMTEAVVAYEDKPREQ---------WLFDYPAQVALTCTQIWWTSDVGLAFSRLEEGYENAMKEYYKKQVSQLNTLITMLIGQLSPGDRQKVMTICTIDVHARDVVAKIIAQKVENSQAFVWLSQLRHRWDEREK---HCFA-NICDAQFLYSYEYLGNTPRLVITPLTDRCYITLTQSLHLTMSGAPAGPAGTGKTETTKDLGRALGIMVYVFNCSEQMDYKSCGNIYKGLAQTGAWGCFDEFNRISVEVLSVVAVQVKSIQDAIRD----KKKRFN--FMGEEINLFPSVGIFITMNPGYAGRTELPENLKALFRPCAMVVPDFELICEIMLVAEGFIEARLLARKFITLYQLCKELLSKQDHYDWGLRAIKSVLVVAGSLKRGDPER---------------------PEDQVLMRALRDFNVPKIVTDDMPVFMGLIGDLFPALDVPRKRDLDFEKFVRESVLDLKLQAEDNFVL--------------KVVQLEELLAVRHSVFVVGNAGTGKSQVLKSLNKTYQNMKR-RPVWADLNPKAVTNDELFGIINPATREWKDGLFSNIMRELANVSHAGP---KWIVLDGDIDPMWIESLNTVMDDNKVLTLASNERIPLNPTMRLVFEISHLRTATPATVSRAGILY--------------------------------INQADLGWNPPVSSWIDKR---EIQSEKANLTILF---DKYLPACLD-----------TLRSRFKKIIPIPEQSMVQMLCHLLECLLTPEHTPPDCHKELYELY----FVFAAIWAFGGALFQDQLVDYRVEFSKWWVTEFKTIKFPSQG---TVFDYYIDPETKKFEPWSKMVPRFEMDP-EIPLQACLVHTTETIRVSYFMERLLERRRPIMLVGNAGTGKSVLVGGKLGSLDPDKYTIKNVPFNYYTTSAMLQAVLEKPLEKKAGRN---YGPPG-SKRLIYFIDDMNMPEVDAYGTVQPHTLIRQHMDYNHWYDRSKLQLKEIHSVQYVSCMNPTS--GSFTINPRLQRHFSVFALSFPGVDALNTIYCS----ILGQHLSREGFSAVVQKSGPQLVQLALDFHQRVTATFLPTAIKFHYIFNLRDLSNIFQGMLFCKSECMK-----TPQDLVKVYLHESNRVYRDKMVEDKDFSTFDKLQSEMVGKFYEDM--EEALEEAKVMNMYCHFALGIGEPRYMPVQSWESLNKTLLEALDSYNEVNAAMNLVLFGDAMSHICRINRILESPRGNALLVGVGGSGKQSLTRLAAFISSLEVFQITLKKGYGITDLKSDLGALCIKAGVKNIGTVFLMTDAQVADEKFLVLVNDLLASGEIPDLYPDDEVENIINSVRNEVRGQGLL-DSRENCWKFFIERVRRQLKVALCFSPVGSKLRVRSRKFPAVVNCTVIDWFHEWPQEALESVSLRF-----LQEVEHIEPEV---------------KDSVSKFMAYVHVSVNKTSKDYLANERRYNYTTPKSFLEQIKLYRNLLALKRKDLTMKMERLENGLQKLNSTSAQVDDLKAKLAAQEVDLKQKNEDADRLIQVVGVETEKVSREKAVADEEEEKVASIAVVVTRKQKDCEEDLAKAEPALIAAQEALNTLNKNNLTELKSFGSPVAAVTNVTAAVMVLMAPGGRVPKDRSWKAAKVMMAKVDAFLDSLMNFNKENIHENCLKAIQP-YLQDPEFKPELVAAKSNAAAGLCSWVINIVKFYEVYCEVEPKRQALNKANAELASAQEKLSVIKAKINHLNENLAKLTAKFEKATADKLKCQQEAETTARTISLANRLVGGLASENVRWAEAVNNFKQQERTLCGDVLLITAFVSYLGYFTKRYRHELMDNTWKPYLSQLKVPIPVTPGLDPLSMLMDDADVAAWQNEGLPADRMSTENATILTSCERWPLMVDPQLQGIKWIKNKYGDNLQVIRIGQRGYLD-----SIERALSAGEVVLIENLEEAVDPVLGPLLGQETIKKG--RYIKIGDKECEYNPRFRLILHTKLANPHYQPELQAQCTLMNFTVTRDGLEDQLLAAVVSMERPDLEELKSNLTKQQNGFKITLKTLEDNLLSRLSSASGNFLGDTELVENLEITKRTAAEIEEKVKEAKVTEAKINEAREHYRPAAARASLLYFIMNDLNKIHPMYQFSLKAFSVVFQKAVLKAAPDEALKQRVLNLIDSITSSVFQYT----TRGLFECDKLTYTAQLAFQILLMNKEINPSELDFLLRYPVQPGVTSPVDFLSHHSWG---------GIKALCSMDEFRNLDRDIESSAKRWKKFVECECPEKEKFPQEW------------KNKTSLQKLCMMRALRPDRMNYAIRDFVEEKLGSKYV--MGRSVDFAVSFE-ESGAATPMFFILSPGVDPLKDVEKHGRTMGYTFDNQNFHNVSLGQGQEVV-AEQALDLAAREGHWVILQNIHLVAKWLGTLEKKLEQHGEGSSQNFRVFISAEPSSSPEGHIIPQGILENSIKITNEPPLGMHANLHKALDNFNQDTLEMCARENEFKSILFSLCYFHAVVAERRKFGPQGWNRSYPFNTGDLTISVNVLYNYLEANS---------KVPYDDLRYLFGEIMYGGHITDDWDRRLCRTYLEEFIKPEMMEGELYL------APGFPLPGNMDYNGYHQYIDDALPAESPYLYGLHPNAEIGFLTQTSEKLFRTVLEMQP-----RDAGSGEGS-------GTSRDEKVKAVLEET---LEKLPEEFNMVELMGKVEE-RSPYVVVALQECERMNILTQEIKRSLKELNLGLKGELTMTNDMENLQNAIYLDQVPDSWTKRAYPSMCGLALWFTDLLNRIRELESWSSDFNLPPA-------VWLAGFFNPQSFLTAIMQSTARRNEWPLDKMSLQCDVLKKNREDFSSPPREGAYVHGLFMEGARWDTQAGVIVDARLKELTPA----IPVIFIKAVPVDKQE------TRNVYQCPVYKTRQRGPTYVWTFNLKTKENPSKWTLAGVAL 4321
BLAST of Cytoplasmic dynein 1 heavy chain 1 vs. Ensembl Cavefish
Match: dnah5 (dynein, axonemal, heavy chain 5 [Source:ZFIN;Acc:ZDB-GENE-110411-177]) HSP 1 Score: 1274.23 bits (3296), Expect = 0.000e+0 Identity = 960/3501 (27.42%), Postives = 1659/3501 (47.39%), Query Frame = 3 Query: 3888 WEKDKPIAGDLTPEEAVNIIQILEGKFNRLKEERENVQKAKEALELTEIGVKPISEE----KVTNALSELHDLKNVWNELKSIWEKIRDMKETPWLSVQPRKLRQDIENLTAQLKELPNSFKQYASFEHVRTLLKMYMKVNASIVELKSEAIKERHWRMLMRKLNVSWSL--NELQLGKVWDIDLVKNEEIIREVLAIAQGEKALEEYLRQITEVWKNYVLELTNYQSKSKIIKGWD---DLFNKVKEHINNVTSMKASPYFKQFEEEATAWEDRLNKINALFDVWIDVQRRWIYLDGIFAGSADIKVLLPVESQRFQSVSTEFLGLMKKVQKSP-LVTDVLNIANVQRQLERLADLLGKIQKSLGEYLERQRSSFPRFYFVGDEDLLEIIGNSXXXXXXXXXXXXMFAGVHSIILSEDEKVILGMMSKEGEELRFISPVSIIEHPRINDWLTAMEKEMRVSLAKYLNVAVKEISGWRTESNIDKDKFMVWLDKYQAQIVVLAAQITWSEAVEASLASGVSLESTMTVVHST----LNMLADTVLYEQPPVRRRKLEHLIIEYVHQRDVLRALHNDGVSSNKNFDWMSQMRFYFDPKQTDPLHQLSIHVANAKFHYGFEYLGVCDRLVQTPLTDRCYLTMTQALEARLGGSPFGPAGTGKTESVKSLGNQLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLSAVSQQIQGIQEALRELMVSKKDSINVELLGKQVHVNPDMAIFITMNPGYAGRSNLPDNLKKLFRSLAMTQPDRQLIAQVMLYSQGFRTAEVLAGKVVPFFKLCDEQLSPQSHYDFGLRALKSVLVSAGNVKRDRIKQEKEKIVARGEEINETAIAEQLPEQEILIQSVMETM-VPKLIADDIPLLYSLLTDVFPGVEYRQAEMKRLREEL-RKVSENKFLVYSDEPNTAGYLWVEKVLQLYQITTIHHGLMMVGPSGSGKTMACRVLLQALENIDGIEGVAHIIDPKSISKDSLYGYMDPNTREWTDGLFTHILRRIIDSVRGESNKRQWIVFDGDVDPEWVENLNSVLDDNKLLTLPNGERLAIPPNVRIMFEVQDLKYATLATVSRCGMVWFSEEVLTTGMILTHFLNELKKVQVMEGEEDFSVNQGDTGADADSKISSSPIIQLQTQVSSILAPFFTEDGLIAKCLDYST-TLEHIMDFTRLRALTSLFSMIKQSIRNMIEYNQSHSDFPLNNEQIENYVAKSLISSVVWSMSGDSKLKVREQLSQYIKNISTV--DLPTV--GGIKNIIDFEVNIQGTWVAWSNKVPQIEVETHKITA--TDVVVPTMDTVRHEALLYTWLAEHRPVLLCGPPGSGKTMTLFSAL-RCLPDMEVV-GLNFSSATTPELMLKTFDQYCEYRKTPNGIVLAPQQLNKWLIFFCDEINLPDMDKYGTQRVISFLRQMVEHHGFYRITD-MQWVSFERIQFVGACNPPTDPGRKPLSHRFLRHVPVVYVDYPGETSLKQIYSTFNRAMLRMLPSLRGYAD---TLTNAMVEFFLKTQERFTHDMQP-----HYIYSPREMTR-WVRGIHEALKPLESLSVEGLVRIWAHEALRLFQDRLVEEDERHWTDD---NINEVAL-KHFPNINKEEALKRPILYSNWLSKDYSAVTQE-ELRDY--------------VKARLKVF---YEEEL---DVPLVLFNQVLDHVLRIDRVFRQPQGHLLLIGVSGAGKTTLSRFVSWINGLSVFQVKVHNKYTAEDFDEDLRNVLRRSGCKGEKITFIMDESNVMDSSFLERMNTLLANGEVPGLFEGDELTTLMTQCKEGAIRE-GLMIDSQEELYKWFTQQICRNLHVVFTMNPSADGLKDKASTSPALFNRCVLNWFGDWSLEAYFQVGKEFTNRLDLERTDYKVPDTLPCIAEGLLPQNPIYRDVVVNALVFVHQTMHQANVRVQKRGGRTAAITPRHYLDLIAHYMKLSAEKRADLEEQQLHLNNGLKKIEQTVDQVEVMQRSLTKKRQELENMNEAANAKLKQMVQDQQEAEQKKTTGQALKEELAKQEQFVNEKQKTVKQELDQVEPTVNEAKQAVQNIRKKDIQEIKAMKNPP------------------NAVKMAVESICLLLGEKTTDWQSILKVIIKDTFVTSILNFNTDDVSDNTRETMKKKYLSNPDYNFEKVNKASNACGPMVKWVLAQISYADILKRVEPLRNELT----ELSDAAEQNRKKSQETEDLIAQLEKSIAKYTEEYATLISQAQTIKSDLASVESKVGRSVALLGSLSSERTRWDSGSETFKAQMATINGDCLLSSAFMAYGGYFDQHMRTSLFNTWCHHLSEADILFRSDLARVEYLSNPDDRLRWQANSLPADDLCVENAIILRRYNRYPLIIDPSGQATTFLLNEYKEKKITKTSFLDDSFRKTLESALRFGTPLLVQDV-ESYDPILNPVLNREVRRTGGRTLITLGDQDIDLSPTFTIFLSTRDPSVEFAPDICSRVTFVNFTVTRSSLQNQCLNAVLKIERPDIDQKRSDLLKAQGEFQLKLRHLEKDLLQSLNEAQGNLLENDKIIARLETLKREAADVAKKVE---ETDVVMQEVESVSTEYVPLAQSCSNIYFTLEAMNQIHFLYQYSLQLMLDIFSSVLINNPELTNVKAASDRLKIITKNLFQVTYNRLARGMLHEDQITFATILARIFLKGSTPIGFLENEFQHFLRSQEATITSSDSNK-----QDNLGLTLHQDQIDSVKRLKKLKVFAKIEEKV-KSTKDIKNWTLTVTPESNVPELWVDDNNYNDEKLSKIAKGMYNLLIIQAIRPDRLLASTQKFIASVLGDTFTESVRGTLDLASIVEVEVTACVPILLCAVQGYDPSGRVEDLASEQGKQLTGIAIGSAEGFSQAEKAINSAAKTGKWVMLKNVHLATSWLVSLEKKIHSLQA-HPNFRLFLTMEITPKLPVNLLRAGRVLVFEPPPGIKANLLRTLSSINNQRMSKEPVERSR-LYFLLAWLNAIVQERLRYVPLGYSKKYEFGESDFKCALDTIDTWVDGAAMGRTNLPPEKIPWVALQTLLGSCIYGGKIDNAFDQRLLNSFLGYLFTEKCFDHNFALVSDADDGSNIAFPESTKHTDILQWVHKLPDLQTPSWLGLPNSAEKVLLTNLGQSLIGNILKMQQSLEDDEELVVGQSKTKRTIEVGDGRPAWMRQLYQSTQTWLQILPKSVTPLQ--RTIENIK--DPMYRCFEREVNSGCNLLASVRKDLEDVAEVCKGAKKPTNHHRSMMADLAKGIIPKMWIRYAIPPGLTVIQWIQDFADRIKQLLHISDTAAKSGVIALRSIQVWLGGLFMAEAYITATRQSVAQNNK-WALEELFLDVELGEGKVDSNT------CVITGLRLMGSEIVDPRTLKL----STLIYKDIDICRLKWIRVEKSQQLEGSSAKDK--VCLPIYLNAARS--TVLFTLYFSTTDSSYDFYKRGVAI 14048 ++KD P+ L P++A + + + + +F+ L + +E L P+++ ++ L+ L L ++N ++ E + + W V ++ ++ + + ++LP + K++ +F ++ + + + + + + A+ RHW+ + ++ + + +L + + L+K +E I ++ A E+ +E+ L+Q+ W N ++++ +++ D ++ + +++ + + S+ ++ Y F+ + W L+ + + W+ VQ WIYL+ +F G DI LP E++RF ++ ++ +M + + P +V + + + L L D L QKSL YLE++R FPRF+FV D LLEI+G + D +Q H +F + S++ + + R+N L + + + L K + KF+ L AQ+ +L Q+ W++ E +L + MT + LN L D + + R K E LI +VHQ+D+ L + + S +F+W+ Q RFYF + L ++ I++ + F Y E+LG DRLV TPLTDRCY+T+ QAL +GG+P GPAGTGKTE+ K +G LG++V+VFNC + DF+ +GRI+ GL Q G+WGCFDEFNR++ +LS +QQI + +E KK + G V +NP+ IF+TMNPGYAGR LP+NLK FR++AM PDRQ+I +V L S GF LA K +KLC+EQLS Q HYDFGLR + SVL + G KR + IV R V+ M + KLI +D PL SL+ D+FPG++ +A L + ++V+E + + W K++QL++ + HG+M +GPSG+GK+ L++A+ + G ++PK+I+ ++G +D T +WTDG+F+ + R+ + + +GE WIV DG VD W+ENLNSVLDDN+ LTL NG+R+ + PN +I+FE ++ A+ ATVSR GMV+ S VL IL +L ++ Q S +L F+ +S +L+ MD + +M++ I+ + + L+ E +E + + +++WS+ + R+++ ++++ ++ DLP + + D+ V G WV W+ +V + + IT + ++VP +D VR + L+ T + + VLL G G+ KT+ + L + P+ LNFSSATTP + ++ + Y + R G P K IF D+IN+P ++++G Q +RQ++E GF+ + ++ + IQF+ A P GR + R R + P S+ +I+ S RG+ + + + +V + + M P HYI++ R+++R W ++ + + V L+ +W HE R+ DR ++ W D N+ E L + + ++ K E + ++L A +E E D+ ++ RL +F Y E + + LV F + H+++I R+ R P+G+ LL+GV G+GK +L+R S+I G +FQ+ + Y + EDL+N+ R +G +G+ I+FI+ ++ + D SFLE MN +L++GEV LF DE+ +++ RE + E L+++F ++ +NLHVV +P PAL + C ++WF W +A V + F + D++ T + + C+ ++D V V Q R R+ +TP YL I Y + EK LE + +N GL+K+++ + V + + L K +EL+ NE A+ LK++ AE+ K Q +K++ ++ + K++L+ +P + EA+ A+Q I+ DI ++ + PP NAVK+ E C+ T WQ LK++ F+ S+ F D +++ E + Y PDYN E + + W A ++ I + V PL+ L L+ A +K E + A+L+ A EY +++ Q + D K+ + +L+ L+ E+ RW S+ F AQ + GD LL++AF++Y G F+Q R L + W + I F +L E L + W LP DDL ++N II+ + R+PL+IDP Q ++ N+ + ++ TS FR LE +L G PLL++DV E DP L+ VL + +TG + +GD+++D+ F ++++T+ P+ + P+I +R + ++FTVT L++Q L V+ E+ ++++ R DL++ + K++ LE LL L +G+L++++ +I L KR + +V +K++ ET+V ++ + EY P+A S +YF + M+ ++ +YQ SL+ L +F L + + S R+ I +++ +N ARG+ E + F +L S I EF ++ + + K D L L + L KL F+ I +++ + K ++W + PE V N Y D+ L + LL+I++ PDR +A +K+I +G+ + E V LDL E E PI+ G DP+ + L Q + +++G + A K + G W +L+N HL +L L + + H +FRL++T E P+ LL+ EPP G+KA L RT IN + + + + R + + +A+L++ VQER +Y PLG+S YEF ++DF + + +D M R + W ++ ++G YGG++ + +D+RLLN+F F+E F+H F D P T LQ++ LP TP GL +A+ + L + ++ IL +Q D G+++ E GR A L+ LP +P + + +E + +PM +E++ +LA VR L D+ G + + R + + IP W + A T+ W + +R +Q ++ + R W+ G F + ++TA RQ + + NK WAL+ + L E+ D T + GL L G+ D R +L ++++ + + R+ E + KD PIY AR+ ++ + T+ + RGVA+ Sbjct: 949 YDKDGPMVMGLAPQDASDRLIMFQNRFDNLYRKFVTFTGGEELFGL------PVTQHPQLLEIRKQLTLLQKLYGLYN---NVIETVNGYYDVLWADVHIERINNELLDFQTRCRKLPRALKEWQAFLDLKKTIDDFSECCPLLELMANRAMMTRHWKRITEVTGHTFEVETDTFKLRNIMEAPLLKYKEEIEDICISAVKERDIEQKLKQVIAEWDNKTFTFAQFKTRGELLLRGDSTSEIISNMEDSLMVLGSLMSNRYNTPFKAQIQKWVQNLSNTTDIIENWMTVQNLWIYLEAVFVG-GDIAKQLPKEAKRFSNIDKSWVKIMTRAHEMPNVVQSCVGDETMGQLLPHLLDQLEICQKSLTGYLEKKRLLFPRFFFVSDPALLEILGQASDSHTIQAHLLNVFDNIKSVVFHDKTR-------------------------RVNHVLISKQVKHHCILFKVMF------------------KFVFLL----AQVGLLGIQMIWTKDSEEALTNARFDRKIMTKTKQSFLELLNTLIDMTTKDLGTMERTKYETLITIHVHQKDIFDDLCHLNIRSPSDFEWLKQCRFYF----IEDLDRMMINITDVGFKYQNEFLGCTDRLVITPLTDRCYITLAQALGMSMGGAPAGPAGTGKTETTKDMGRCLGKYVVVFNCSDQMDFRGLGRIYKGLAQSGSWGCFDEFNRIDLSVLSVAAQQIAVVLTGKKE---RKKTFTFTD--GDIVEMNPEFGIFLTMNPGYAGRQELPENLKINFRTVAMMVPDRQIIIRVKLASCGFIDNVELARKFFTLYKLCEEQLSKQVHYDFGLRNILSVLRTLGAAKRSNPTDTESTIVMR----------------------VLRDMNLSKLIDEDEPLFLSLIEDLFPGIQLDKAGYPELEAAIDKQVTEAGLINHPP--------WRLKIIQLFETQRVRHGMMALGPSGAGKSTCIHTLMKAMTDC-GQPHREMRMNPKAITAPQMFGRLDVATNDWTDGIFSTLWRKTLRAKKGE---HIWIVLDGPVDAIWIENLNSVLDDNRTLTLANGDRIPMAPNCKIVFEPHNIDNASPATVSRNGMVFMSSSVLNWSPILEGWL-----------------------------------MKRSAQESEVLRHLFSSS--FPTLYQFSIQSLDFKMDMLEAFVIMQCINMLQGLIQPKDQGGE------LSREHME----RLYVFALMWSIGALLEQDDRKKMEHWLRHHDSIHLDLPYIPPDSQDTMFDYHVTNDGQWVHWNLRVEEY-IYPKDITPEYSSILVPNVDNVRTDFLIQTIAKQGKAVLLIGEQGTAKTVIIKGYLSKSNPESHTAKSLNFSSATTPLMFQRSVESYVDKRM---GTTYGPPAGKKMSIFI-DDINMPVINEWGDQVTNEIVRQLMEQKGFFNLEKPGEFTNIVDIQFLAAMIHPGG-GRNDIPQRLKRQFSIFNCTLPSNASIDKIFGVIGTGHY---CSQRGFEEDVRKVVSRLVPLTRRLWQMTKVKMLPTPANFHYIFNLRDLSRIWQGMLNVNADVIHTPKV--LLCLWKHECKRVIADRFTSPEDVAWFDSMLANLVEEELGEEYRDVVKPEV---DAYFVDFLQDAPEATGEEPENADFDMPKVYEPIASFPSLRDRLNMFLGLYNESIRGAGMDLVFFTDAMIHLVKISRIIRTPRGNALLVGVGGSGKQSLTRLASFIAGYGIFQITLTRSYNTANLMEDLKNLYRTAGQQGKGISFIITDNEIKDESFLEYMNNVLSSGEVSNLFARDEMDEILSDLIPVMKREFPRRPPTNENLHEYFMSRVRQNLHVVLCFSPF-----------PALISGCTMDWFSRWPKDALVAVSEHFLSSYDIDCTPQVKGEVVQCMGS--------FQDGVAEKCVDYFQ-----------RYRRSTHVTPMSYLSFIQGYKAIYKEKH--LESVKFAMNTGLQKLKEASESVAALSKELEVKEKELQIANEKADMVLKEVTVKAHAAEKVKIEVQKVKDKAQAIVDSISADKAIAKEKLEAAKPALEEAEAALQTIKPSDIATVRTLARPPHLIMRIMDCVLLLFQRRLNAVKIDAEKNCI-----TPSWQESLKLMTAGNFLGSLQQFPKDTINEEVVELLTP-YFDMPDYNIETAKRVCGNVAGLCSWTKAMATFFSINREVLPLKANLVVQENRLAIAHADLQKAQAELDAKQAELDVVQA----EYEKAVTEKQMLLEDAERCRHKMQTASSLISGLAGEKARWTEQSKEFAAQTKRLVGDVLLATAFLSYSGPFNQEFRNLLLSDWQKEMRARCIPFGINLNLTEMLIDAPTVSEWNLQGLPNDDLSIQNGIIVTKAARFPLLIDPQTQGKIWIRNKEAKNELQITSLNHKYFRNHLEDSLSLGRPLLIEDVGEELDPALDNVLEKNFIKTGSTYKVKVGDKEVDVMKGFRLYVTTKLPNPAYTPEISARTSIIDFTVTMRGLEDQLLGRVILTEKQELEKDRMDLVEDVMANKRKMKELEDSLLYRLTSTKGSLVDDESLIVVLSNTKRTSEEVTQKLQIAAETEV---KINAAREEYRPVATRGSILYFLITEMSMVNVMYQTSLRQFLGLFDLSLARS---SKSPITSKRIGNIIEHMTYEVHNYAARGLYEEHKFLFTLLLTLKIDMQSNRIK--HEEFLTLIKGGASLDLKACPPKPSKWIPDMTWLNLVE--------LSKLWQFSDILDQIGRHEKQWRSWF-----DKEAPEEEVIPNAY-DQSLDCFKR----LLLIRSWCPDRTIAQARKYIVDSMGERYAEGV--ILDLERTWE-ESDPRTPIICLLSMGSDPTDIIIALGKRQKVETAYVSMGQGQEV-HARKLLQQFMANGGWALLQNCHLGLDFLDELMDTVTETDSIHESFRLWITTETHRNFPITLLQMSIKFTNEPPQGLKAGLKRTYQGINQELLDVSNMVQWRPMLYSVAFLHSTVQERRKYGPLGWSIPYEFNQADFNATVQFVQNHLDDMDMKR------GVSWTTVRYMIGEIQYGGRVTDDYDKRLLNTFAKVWFSETMFNHEFQFYKD------YHIPRCTSVDQYLQYIQGLPAYDTPEVFGLHPNADITYQSKLAKDVLDTILSIQPK---DSSSGGGETR-----EAAVGRLA---------DDMLEKLPPDYSPFEVMKRLETMGRLEPMNIFLRQEIDRMQRVLALVRSTLTDLKLAIDGTIVMSENLRDALDCMYDARIPARW-KKASWASSTLGFWFTELLERNQQF--------QAWIFEGRPNCFWMTGFFNPQGFLTAMRQEITRANKGWALDRMVLCNEVTRWMKDDITQPPQEGVYVYGLYLEGAGW-DRRNCRLVDSKPKVLFEMMPVVRM---------YAENNGVKDSRLYSCPIYKKPARTDQNIIAAVDLRTSQRPEYWILRGVAL 4168
BLAST of Cytoplasmic dynein 1 heavy chain 1 vs. Ensembl Cavefish
Match: dnah12 (dynein, axonemal, heavy chain 12 [Source:ZFIN;Acc:ZDB-GENE-090311-9]) HSP 1 Score: 1261.13 bits (3262), Expect = 0.000e+0 Identity = 915/3267 (28.01%), Postives = 1607/3267 (49.19%), Query Frame = 3 Query: 4314 LKSEAIKERHWRMLMRKLNVSWSLNE-LQLGKVWDIDLVKNEEIIREVLAIAQGEKALEEYLRQITEVWKNYVLELTNY---QSKSKIIKGWDDLFNKVKEHINNVTSMKASPYFKQFEEEATAWEDRLNKINALFDVWIDVQRRWIYLDGIFAGSADIKVLLPVESQRFQSVSTEFLGLMKKVQKSPLVTDVLNIANVQRQLERLADLLGKIQKSLGEYLERQRSSFPRFYFVGDEDLLEIIGNSXXXXXXXXXXXXMFAGVHSIILSEDEKVILGMMSKEGEELRFISPVSIIE-HPRINDWLTAMEKEMRVSLAKYLNVAVKEISGWRTESNIDKDKFMVWLDKYQAQIVVLAAQITWSEAVEASLASGVS-LESTMTVVHSTLNMLADTVLYEQPPVRRRKLEHLIIEYVHQRDVLRALHNDGVSSNKNFDWMSQMRFYFDPKQTDPLHQLSIHVANAKFHYGFEYLGVCDRLVQTPLTDRCYLTMTQALEARLGGSPFGPAGTGKTESVKSLGNQLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLSAVSQQIQGIQEALRELMVSKKDSINVELLGKQVHVNPDMAIFITMNPGYAGRSNLPDNLKKLFRSLAMTQPDRQLIAQVMLYSQGFRTAEVLAGKVVPFFKLCDEQLSPQSHYDFGLRALKSVLVSAGNVKRDRIKQEKEKIVARGEEINETAIAEQLPEQEILIQSVMETMVPKLIADDIPLLYSLLTDVFPGVEYRQAEMKRLREELRKVSENKFLVYSDEPNTAGYLWVEKVLQLYQITTIHHGLMMVGPSGSGKTMACRVLLQAL-----ENIDGIEGVAH-IIDPKSISKDSLYGYMDPNTREWTDGLFTHILRRIIDSVRGESNKRQWIVFDGDVDPEWVENLNSVLDDNKLLTLPNGERLAIPPNVRIMFEVQDLKYATLATVSRCGMVWFSEEVLTTGMILTHFLNELKKVQVMEGEEDFSVNQGDTGADADSKISSSPIIQLQTQVSSILAPFFTEDGLIAKCLDYSTTLEHIMDFTRLRALTSLFSMIKQSIRNMIEYNQSHSDFPLNNEQIENYVAKSLISSVVWSMSGDSKLKVREQLSQYIKNISTVDL---PTVGGI---------KNII---DFEVNIQGTWVAWSNKVPQIEVETHKITATDVVVPTMDTVRHEAL--LYTWLAEHRPVLLCGPPGSGKTMTLFSAL-------RCLPDMEVVGLNFSSATTPELMLKTFDQYCEYRKTPNGIVLAPQQLNKWLIFFCDEINLPDMDKYGTQRVISFLRQMVEHHGFYRITDMQWVSFERIQFVGACNPPTDPGRKPLSHRFLRHVPVVYVDYPGETSLKQIYSTFNRAMLRM--LPS-LRGYADTLTNAMVEFFLKTQERF-THDMQPHYIYSPREMTRWVRGIHEALKPLESL-SVEGLVRIWAHEALRLFQDRLVEEDERHWTDDNINEVALKHFP--------NINKEEALKRPILYSNWLSKDYSAV--------TQEELRDYVKARLKVFYEEELD-VPLVLFNQVLDHVLRIDRVFRQPQGHLLLIGVSGAGKTTLSRFVSWINGLSVFQVKVHNKYTAEDFDEDLRNVLRRSGCKGEKITFIMDESNVMDSSFLERMNTLLANGEVPGLFEGDELTTLMTQCKEGAIREGLMIDSQE------ELYKWFTQQICRNLHVVFTMNPSADGLKDKASTSPALFNRCVLNWFGDWSLEAYFQVGKEFTNRLDLERTDYKVPDTLPCIAEGLLPQNPIYRDVVVNALVFVHQTMHQANVRVQKRG----GRTAAITPRHYLDLIAHYMKLSAEKRADLEEQQLHLNNGLKKIEQTVDQVEVMQRSLTKKRQELENMNEAANAKLKQMVQDQQEAEQKKTTGQALKEELAKQEQFVNEKQKT-VKQELDQVEPTVNEAKQAVQNIRKKDIQEIKAMKNPPNAVKMAVESICLL-------------LGEKTTDWQSILKVIIKD-TFVTSILNFNTDDVSDNTRETMKKKYLSNPDYNFEKVNKASNACGPMVKWVLAQISYADILKRVEPLRNEL--TELSDAA-----EQNRKKSQETEDLIAQLEKSIAKYTEEYATLISQAQTIKSDLASVESKVGRSVALLGSLSSERTRWDSGSETFKAQMATINGDCLLSSAFMAYGGYFDQHMRTSLFNTWCHHLSEADILFRSDLARVEYLSNPDDRLRWQANSLPADDLCVENAIILRRYNRYPLIIDPSGQATTFLLNEYKEKKITKTSFLDDSFRKTLESALRFGTPLLVQDV-ESYDPILNPVLNREVRRTGGRTLITLGDQDIDLSPTFTIFLSTRDPSVEFAPDICSRVTFVNFTVTRSSLQNQCLNAVLKIERPDIDQKRSDLLKAQGEFQLKLRHLEKDLLQSLNEAQGNLLENDKIIARLETLKREAADVAKKVEETDVVMQEVESVSTEYVPLAQSCSNIYFTLEAMNQIHFLYQYSLQLMLDIFSSVLINNPELTN-VKAASDRLKIITKNLFQVTYNRLARGMLHEDQITFATILARIFLKGSTPIGFLENEFQHFLRSQEATITSSDSNKQDNLGLTLHQDQIDSVKRLKKLKVFAKIEE-------KVKSTKDIKNWTLTVTPESNVPELWVDDNNYNDEKLSKIAKGMYNLLIIQAIRPDRLLASTQKFIASVLGDTFTESVRGTLDLASIVEVEVTACVPILLCAVQGYDPSGRVEDLASEQ---GKQLTGIAIGSAEGFSQAEKAINSAAKTGKWVMLKNVHLATSWLVSLEKKIHSLQ---AHPNFRLFLTMEITPKLPVNLLRAGRVLVFEPPPGIKANLLRT-----------LSSINNQRMSKEPVERSRLYFLLAWLNAIVQERLRYVPLGYSKKYEFGESDFKCALDTIDTWVDGAAMGRTNLPPEKIPWVALQTLLGSCIYGGKIDNAFDQRLLNSFLGYLFTEKCFDHNFALVSDADDGSNIAFPESTKHTDILQWVHKLPDLQTPSWLGLPNSAEKVLLTNLGQS-LIGNILKMQQSLEDDEELVVGQSKTKRTIEVGDGRPAWMRQLYQSTQTWLQILPKSV---TPLQRTIENIKDPMYRCFEREVNSGCNLLASVRKDLEDVAEVCKGAKKPTNHHRSMMADLAKGIIPKMWIRYAIPPGLTVIQWIQDFADRIKQLLHISDTAAKSGVIALRSIQVWLGGLFMAEAYITATRQSVAQNNKWALEELFLDVEL 13754 L + I+ RHW + +N + N L KV +L E + A A E +LE+ L+ + E W ++ +++ +S I+ D++ + + I +M+ SP+ K FE+E AWE+RL +I D W+ VQ +W+YL+ IF+ S DI +P E Q FQ+V + +M+ K P V ++ + +L+ +LL +I K L YLE++R FPRF+F+ ++++LEI+ +KD ++Q H KK F G+ + + I M S EGE + I +S E + WL +E M S+ +N R+ + K W+ ++ Q+V+ +Q+ W++ V ++ SGV L++ + S L + + V + P R L L+ VH RDV+ + GVS +F W++Q+R+Y++ + + + N Y +EYLG RLV TPLTDRCY T+ A LGG+P GPAGTGKTE+ K L L +VFNC + D+ AMG+ F GL GAW CFDEFNR+E +LS V+QQI IQ A+ K + + E G ++ +NP+ + ITMNPGYAGRS LPDNLK LFR++AM P+ LIA++ LYS GF A+ L+ K+V ++LC EQLS Q HYD+G+RA+K+VLV+AGN+K + E E I +L++S+ + PK ++ DIPL + +D+FPG+ A+ + + ++ + ++ +P ++++K++Q Y++ + HG M+VG +GKT VL L + E V + ++PKSI+ L+G DP + EWTDG+ + R + E+ R+W+VFDG +D W+E++N+VLDDNK L L +GE + + + ++FE DL A+ ATVSRCGM++ L ++T +LN L Q ++ +E+ S+ +++L + ++ P L C + +T + + +LT LF M+ + ++ P N+ I ++ + S+VWS+ G RE+ Q+++ I + L P + K ++ +E +G W+ W+ + + + D++VPT+DT+ L + + RP+L GP G+GK++ + L R LP +NFS+ T+ + R+ G+ P + K I F D++N+P M+ +G Q I LRQ +H +Y + D ++ +Q + A PP GR ++ RFLRH + ++ + ++ +I+S LR P+ + + A +E + K E + HY ++ R+ +R V+G L ESL + ++R++ HE R+F DRLV++ +R W + + +HF ++ E R +L+ ++++ D A + E V++ L + + + + LV+F VL+H+ RI RV +QP G+ LL+GV G+G+ +++R +++ +++FQ ++ Y ++ EDL+ +L+++G KG+K F++ ++ + + +FLE ++++L GEVP LF DE +M A+R ++ L+ +F + NLHVV +P D +++ P+L N C +NWF W EA +V +F L++ +D++ + + + +T H + + + ++ GR +TP YL+LIA + L KR + + NGL K+ QV M++ L + +LE + N K+ Q+++ + + K+ ++EE A Q+ + K + +L + P + A A+ ++ D+ +K+MKNPP+ VK+ + ++C++ G+K D+ K ++ D F+ + ++ D++ ++ +Y++NPD++ KV KAS+A + KW+ A Y + K V P + L + S AA Q R + +E ED +A L+K++ + TEE A L Q DL + K+ R+ L+G L E+TRW ++ + + GD L+S+ +AY G F R + W +I D + + L +P W + LP D ++N +I+ R+PL+IDP GQA ++ N +E + D + +TLE+ ++FGTPLL+++V E DP L P+L +++ + GG I LG+ I+ S F +++T+ + + P++ ++V+ +NF +T L++Q L V+ ERP+++++R+ L+ + +L+ +E +L++L ++GN+LE++ I L++ K + +++KK + + ++ Y P+A+ S ++F++ + I +YQYSL ++++ IN+ + +N K RL+ + + Y + R + +D++ F+ +L L I + E FL + + ++ N N L D + R L + + +K+ N TP +P+ W D KLS K ++I + +RPD++ + +I LG F E DL+ + + +P++ G DP + A+++ G I++G +G A K I SA K G WV L+N HLA SW+ +LEK HP+FRL+LT +P PV +L+ G + EPP G++ NLL++ S+ +N+ + E +L + + + +A+VQER ++ PLG++ Y F ESD + ++ + +V+ E++P+ A+ L G C YGG++ + +D+RLL + L + + ++ + S + G + P+S + D ++++ LP Q P G+ + + + +L Q+ L+ + L + Q G T I D R LP++ + L + ++ M +E+ NL ++R L+++ + KG ++ L G +P+ W + + P + +I DF R+K L DT K V WL G F +A++T Q+ A+ ++ L D E+ Sbjct: 737 LCNPGIRARHWEQMSEIVNHDLTPNSGTTLRKVLKQNLSAYMEHFETISAAASKEFSLEKALQNMVETWD--IISFSHHAHRESGVSILTAVDEIQTMLDDQIVKTQTMRGSPFIKPFEKEIKAWEERLIRIQDTIDEWLKVQAQWLYLEPIFS-SQDIMQQMPEEGQLFQTVDKHWREVMRHCVKDPKVLPATSLTGLLEKLQESNNLLEQIMKGLNAYLEKKRLFFPRFFFLSNDEMLEILSETKDPLRVQPHLKKCFEGIAKLDFLPNLD-IQAMYSSEGERVELIQLISTSEARGAVEKWLVQVEDVMLSSIRDVIN---------RSRLAYPETKRSQWVREWPGQVVLCTSQMYWTQEVHEAIRSGVGGLKNYYNQLQSQLKDIVELVRGKLPKQTRTTLGALVTIDVHARDVVMEMIEKGVSHETDFQWLAQLRYYWNNDN------VRVCIINCDVKYAYEYLGNSPRLVITPLTDRCYRTLIGAFYLNLGGAPEGPAGTGKTETTKDLAKALAVQCVVFNCSDGLDYLAMGKFFKGLASSGAWACFDEFNRIELEVLSVVAQQILCIQRAIE----MKLEFFDFE--GTELRLNPNCFVAITMNPGYAGRSELPDNLKVLFRTVAMMVPNYALIAEISLYSYGFLNAKPLSVKIVMTYRLCSEQLSSQFHYDYGMRAVKAVLVAAGNLKL-KFPDENEDI--------------------LLLRSIKDVNEPKFLSHDIPLFNGITSDLFPGISLPAADYQLFLDCAQECCKK----HNVQPVK---VFLDKMIQTYEMMIVRHGFMLVGEPFAGKTKVLHVLADTLTLMNERGYNDEEKVQYRTVNPKSITMGQLFGQFDPVSHEWTDGIVANTFR---EYASAETPDRKWVVFDGPIDTLWIESMNTVLDDNKKLCLMSGEIIQMSNQMSLIFEAMDLSQASPATVSRCGMIYMEPSQLGWLPLVTSWLNTLP--QPLQTQEN-----------------STLLLEL---FNWLIPPALR--MLRKNCREVVST----TNSNTVVSLTRLFEML---------LTEPVTEEP-GNKNIRTWIMAAFAFSLVWSIGGSCDRDSRERFDQFLREILSGKLEEHPIPAAVSKWECPFNDKGLVYDYSYEFKGKGCWIHWNESIKNVTLGDKNTKVQDIIVPTIDTIFCTLFTTLIIFFSPFRPLLFVGPTGTGKSVYVKEKLMNNLNKERYLP----FFINFSARTSANQSQNIIMARLDKRR--KGVFGPP--MGKKCIIFVDDMNMPAMEVFGAQPPIELLRQYFDHGNWYDLKDTSKITLVDVQLISAMGPPGG-GRNAVTPRFLRHFNICSMNAFSDDTMSRIFSNVVAFYLRNNDFPNDCFSIGNQIVAATLEVYKKAMENLLPTPAKSHYTFNLRDFSRVVQGC--LLLKKESLENKRTMIRLFVHEVFRVFYDRLVDDQDRDWLYKLMKNIVKEHFKESFDTVFEHLKLCEEDMRSLLFGDYMTPDVEASERLYAEVPSMESFSQVVESYLTEYNQTHKNRMNLVIFRYVLEHLSRISRVLKQPGGNALLVGVGGSGRQSITRLATFMADMTLFQPEISKNYGMNEWREDLKLLLKKAGVKGQKTVFLLTDAQIKEEAFLEDVDSVLNTGEVPNLFAVDEKQEIMEVMH--AVRPIAQAGNKSLEFSPLALFAFFVNRCRENLHVVVAFSPIGDAFRNRLRQFPSLINCCTINWFQPWPEEALERVANKFLETLEM--SDHERQEVM-----------------------LICKTFHTSAIHLSEKFLSELGRHNYVTPTSYLELIAAFRLLLTNKRDTVMNAKKRYTNGLDKLAFAESQVGEMKKELVDLQPKLEQA-KIDNIKMVQVIEVESVQVEAKSKVVRVEEEAASQKAAEAQALKNECESDLAEAIPALEAALSALDTLKPSDVTIVKSMKNPPSGVKLVMAAVCVMKDIKPEKINDPAGTGQKILDYWGPSKKLLGDMNFLRDLKVYDKDNIPAPVMHKIRSEYMTNPDFDPTKVAKASSAAEGLCKWITAMEVYDRVAKVVAPKKANLIVAQQSLAATMALLNQKRAELKEVEDRLAALKKTLEEKTEEQAQLQFQV-----DLCA--RKLERAEKLIGGLGGEKTRWSKAADDLQNTYDNLTGDVLISAGVIAYLGAFTAGFRQNCTKEWTKLCKSKNIPSSDDFSLSKTLGDPIKIRAWNISGLPTDSFSIDNGVIVSNSRRWPLMIDPQGQANKWVKNSERENNLNVIKLTDADYMRTLENCIQFGTPLLLENVGEELDPSLEPLLLKQIFKQGGMDCIRLGESVIEFSSDFRFYITTKLRNPHYLPELATKVSLLNFMITPEGLEDQLLGIVVAKERPELEEERNALILQSAANKKQLKEIEDKILETLQSSEGNILEDESAIQILDSAKIMSNEISKKQQIAEKTELKIAESREGYRPIAKHSSILFFSIADLANIDPMYQYSLNWFVNLY----INSIQDSNKSKILEKRLRYLINHFTYNLYCNVCRSLFEKDKLLFSFLLCSNLLLAKKEIEYAEF---MFLLTGGVGLQNNVPNPDPNW---LQDKSWDEICRASDLPGLQGLRYPPFCHFLPIYDSKEPYN-----TP---LPKPWCD-------KLSDFQK----MIIYRCLRPDKIEPAISNYITGKLGKKFVEP--PPFDLSKSYN-DSNSTIPLVFVLSPGADPMASLLKFANDKNMGGANFKSISLGQGQG-PIAVKMIQSAMKEGTWVCLQNCHLAVSWMSTLEKICEDFSPETCHPDFRLWLTSYPSPMFPVTILQNGVKMTNEPPTGLRLNLLQSYLSDPVSDPQFFSACSNKELVWE-----KLLYGVCFFHALVQERKKFGPLGWNIPYGFNESDLRISIRQLQLFVNSY---------EEVPFEAITYLTGECNYGGRVTDDWDRRLLLTILADFYNKDIIENPRYMFSPS--GKYYSPPKSI-YEDYVEFIRNLPATQHPEVFGMHENVD--ISKDLQQTKLLFDSLILTQGGGSKGGASSGGDSTLMDI-ANDIRTK---------------LPENFNIDSALNKFPVLYEESMNTVLVQEMERYNNLCNTIRVSLQNLLKAIKGLVVMDAELEAIAGSLLVGKVPEKWAKRSYPSLKPLGSYITDFLTRLKFLQDWYDT-TKPNVF-------WLSGFFFTQAFLTGAMQNYARKYSIPIDLLSFDYEV 3787
BLAST of Cytoplasmic dynein 1 heavy chain 1 vs. Ensembl Sea Lamprey
Match: DNAH6 (dynein axonemal heavy chain 6 [Source:HGNC Symbol;Acc:HGNC:2951]) HSP 1 Score: 1340.48 bits (3468), Expect = 0.000e+0 Identity = 957/3341 (28.64%), Postives = 1668/3341 (49.93%), Query Frame = 3 Query: 4059 KVTN--ALSELHD-LKN---VWNELKSIWEKI-RDMKETPWLSVQPRKLRQDIENLTAQLKELPNSFKQYASFEHVRTLLKM---YMKVNASIVE-LKSEAIKERHWRMLMRKLNVSWSLNE--LQLGKVWDIDLVKNEEIIREVLAIAQGEKALEEYLRQITEVWKNY-VLELTNYQSKSK-IIKGWDDLFNKVKEHINNVTSMKASPYFKQFEEEATAWEDRLNKINALFDVWIDVQRRWIYLDGIFAGSADIKVLLPVESQRFQSVSTEFLGLMKKVQKSPLVTDVLNIANVQRQLERLADLLGKIQKSLGEYLERQRSSFPRFYFVGDEDLLEIIGNSXXXXXXXXXXXXMFAGVHSIILS------EDEKV----ILGMMSKEGEELRFISPVSIIEHPRINDWLTAMEKEMRVSLAKYLNVAVKEISGW-RTESNIDKDKFMVWL-DKYQAQIVVLAAQITWSEAVEASLASGVS--LESTMTVVHST---LNMLADTVLYEQPPVRRRKLEHLIIEYVHQRDVLRALHNDGVSSNKNFDWMSQMRFYFDPKQTDPLHQLSIHVANAKFHYGFEYLGVCDRLVQTPLTDRCYLTMTQALEARLGGSPFGPAGTGKTESVKSLGNQLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLSAVSQQIQGIQEALRELMVSKKDSINVELLGKQVHVNPDMAIFITMNPGYAGRSNLPDNLKKLFRSLAMTQPDRQLIAQVMLYSQGFRTAEVLAGKVVPFFKLCDEQLSPQSHYDFGLRALKSVLVSAGNVKRDRIKQEKEKIVARGEEINETAIAEQLPEQEILIQSVMETMVPKLIADDIPLLYSLLTDVFPGVEYRQAEMKRLREELRKVSENKFLVYSDEPNTAGYLWVEKVLQLYQITTIHHGLMMVGPSGSGKTMACRVLLQALENIDGIEGVAH----------IIDPKSISKDSLYGYMDPNTREWTDGLFTHILRRIIDSVRGESNKRQWIVFDGDVDPEWVENLNSVLDDNKLLTLPNGERLAIPPNVRIMFEVQDLKYATLATVSRCGMVWFSEEVLTTGMILTHFLNELKKVQVMEGEEDFSVNQGDTGADADSKISSSPIIQLQTQVSSILAPF--FTEDGLI---AKCLDYSTTLEHIMDFTRLRALTSLFSMIKQSIRNMIEYNQSHSDFPLNNEQIENYVAKSLISSVVWSMSGDSKLKVREQLSQYIKNI----STVDLPTVGGI-KNIIDFEVNIQGTWVAWSNKVPQIEVETHKITATDVVVPTMDTVRHEALLYTWLAEHRPVLLCGPPGSGKTMTLFSAL-RCLPDMEVVGL--NFSSATTPELMLKTFDQYCEYRKTPNGIVLAPQQLNKWLIFFCDEINLPDMDKYGTQRVISFLRQMVEHHGFYRITDMQWVSFE-----RIQFVGACNPPTDPGRKPLSHRFLRHVPVVYVDYPGETSLKQIYSTFNRAMLRMLP-SLRGYADTLTNAMVEFFLK-TQERFTHDMQPHYIYSPREMTRWVRGIHEALKPLESLSVEG---LVRIWAHEALRLFQDRLVEEDERHWTDDNINEVALKHFP-NINKEEALKRPILYSNWLSKDYSAVTQ--EELRDYVKARLKVFYEEELD---------VPLVLFNQVLDHVLRIDRVFRQPQGHLLLIGVSGAGKTTLSRFVSWINGLSVFQVKVHNKYTAEDFDEDLRNVLRRSGCKGEKITFIMDESNVMDSSFLERMNTLLANGEVPGLFEGDELTTLMTQCKEGAIREGLMIDSQEELYKWFTQQICRNLHVVFTMNPSADGLKDKASTSPALFNRCVLNWFGDWSLEAYFQVGKEFTNRLDLERTDYKVPDTLPCIAEGLLPQNPIYRDVVVNALVFVHQTMHQANVRVQKRGGRTAAITPRHYLDLIAHYMKLSAEKRADLEEQQLHLNNGLKKIEQTVDQVEVMQRSLTKKRQELENMNEAANAKLKQMVQDQQEAEQKKTTGQALKEELAKQEQFVNEKQKTV---KQELDQVEPTVNEAKQAVQNIRKKDIQEIKAMKNPPNAVKMAVESICLLLGEKTTDWQSILKVIIKDTFVTSILNFNTDDVSDNTRETMKKKYLSNPDYNFEKVNKASNACGPMVKWVLAQISYADILKRVEPLRNELTELSDAAEQNRKKSQETEDLIAQLEKSIAKYTEEYATLISQAQTIKSDLASVESKVGRSVALLGSLSSERTRWDSGSETFKAQMATINGDCLLSSAFMAYGGYFDQHMRTSLFNTWCHHLSEADILFRSDLARVEYLSNPDDRLRWQANSLPADDLCVENAIILRRYNRYPLIIDPSGQATTFLLNEYKEKKITKTSFLDDSFRKTLESALRFGTPLLVQDV-ESYDPILNPVLNREVRRTGGRTLITLGDQDIDLSPTFTIFLSTRDPSVEFAPDICSRVTFVNFTVTRSSLQNQCLNAVLKIERPDIDQKRSDLLKAQGEFQLKLRHLEKDLLQSLNEAQGNLLENDKIIARLETLKREAADVAKKVEETDVVMQEVESVSTEYVPLAQSCSNIYFTLEAMNQIHFLYQYSLQLMLDIFSSVLINNPELTNVKAASDRLKIITKNLFQVTYNRLARGMLHEDQITFATILARIFLKGSTPIGFLENEFQHFLRSQEATITSSDSNKQD---------NLGLTLHQDQIDSVKRLKK-------LKVFAKIEEKVK------STKDIKNWTLTVTPESNVPELWVDDNNYNDEKLSKIAKGMYNLLIIQAIRPDRLLASTQKFIASVLGDTFTESVRGTLDLASIVEVEVTACVPILLCAVQGYDPSGRVEDLASEQG--KQLTGIAIGSAEGFSQAEKAINSAAKTGKWVMLKNVHLATSWLVSLEKKIHSLQA-----HPNFRLFLTMEITPKLPVNLLRAGRVLVFEPPPGIKANLLRTLSSINNQRMSKEPVERS--RLYFLLAWLNAIVQERLRYVPLGYSKKYEFGESDFKCALDTIDTWV-DGAAMGRTNLPPEKIPWVALQTLLGSCIYGGKIDNAFDQRLLNSFLGYLFTEKCFDHNFALVSDADDGSNIAFPEST--KHTDILQWVHKLPDLQTPSWLGLPNSAEKVLLTNLGQSLIGNILKMQQSLEDDEELVVGQSKTKRTIEVGDGRPAWMRQLYQSTQTWLQILPKSVTPLQRTIENIKDPMYRCFEREVNSGCNLLASVRKDLEDVAEVCKGAKKPTNHHRSMMADLAKGIIPKMWIRYAIPPGLTVIQWIQDFADRIKQLLHISDTAAKSGVIALRSIQVWLGGLFMAEAYITATRQSVAQNNKWALEEL 13736 +VTN AL+E+ D LK +W+ L WE ++ E + ++ P +L ++ A+ ++ N ++ +V LLK +++ +V L++ ++K RHW ML + E L L + ++++ E I++V A GE +LE L+++ + WK + L + SK I+ G D++ + + I N++++ +S Y + W+ +L N + W+ QR W+YL+ IF+ + DI+ LP E++ F V + +M+K+ + P + + LL +IQK L YLE +R FPRFYF+ +++LLEI+ +++ + +Q H +K F + + + E E+ IL M+S EGE++ + + DWL +E+ M SL + +A+ E RTE W+ +Q+V+ AQ+ W + L G L+S LN LA V P + R + LI VH RD++ + + V + NF+W Q+R+Y+D + L +A +++ YG+EYLG C RLV TPLTDRCYL + AL+ LGG+P GPAGTGKTE+ K L L +VFNC + D++ MGR F GL Q GAW CFDEFNR++ +LS ++QQ+ I+ A +K E G+++ + A FITMNPGYAGR+ LPDNLK LFR +AM P+ LIA+V+LYS+GF ++ VLA K+ +KLC EQLS Q HYDFG+RA+KSVLV AG++KR+ L E +LI+++ ++ +PK +ADD L +L+D+FPGVE + L+ + + + L A V KV+QLY+ + HG+M+VGP+G GKT L AL ++ H +++PKSIS LYG ++ T EW DGL +R +V +S +WIV DG VD W+ENLN+VLDDNK+L L N ER+ + P + ++FEVQDLK A+ ATVSRCGMV+ E L + ++N + GE DTG I+A F + EDGL KC T +D +++ L+ L + + D + + ++ + V ++ + +W++ G+ +Q ++K+ LP+ G + +D++ W VP ++ +++VPT DT+R L+ LA VL G G GK++ L + + + V L NFS+ T+ + + E ++ I+ AP + K +I F D++N+P +D+YG+Q I LRQ + GFY M W + R C PP GR P++ RF+RH ++ + P E SLKQI+ L P +++ A + A VE + + + E + HYI++ R++++ ++GI + +S +V + R++ HE R+F DRL+ +++ + + + E+A K F + E +K PIL+ +++ + E+L D K LK ++ LD + LV F ++HV RI R+ RQ +G+ LL+GV G GK +L+R + G FQ+++ Y+ + F EDLR + +G + + F+ ++ ++ FLE +N +L +GEVP LFE DEL ++ + A G+ +++E+ ++F ++ LH+V M+P D + + P++ N C ++WF W EA V K F +DL + K + C+ +H ++ + R TP YL+LI Y+ + EKR+ L + + NGL K+ +T + V+ +Q L+ L+ +E A ++++ DQ+ A+Q + + + E+ A + E Q +++LD+ P + A +A+ ++ + DI E++ NPP V+ +E+IC++L +K DW S +++ F+ + +++ +++S++ + +K Y++N D+ EKV + S AC M WV A Y+ +LK V P R L + + + + Q+E I +++ +++ +++ ++A ++++ R+ L +L E+ RW F+ ++ + G+ ++SA +AY G F H R L + W E I ++ + + L +P + +W + LP D + EN I++ R R+PL+IDP QA ++ N+ + + D +F +TLE+A+R G P+L++++ E+ DP L P+L ++ +GGR LI LGD D+D F +++T+ + + P++C +VT +NFTVT+S L++Q L+ V+++E+P+++++R++L+ + +L+ +E +L+ L ++GN+L+N+++I L+ K + + +++E + + + + +Y P+A S +YF + ++++I +YQYSL+ +F+ + + + +++ ++RL+++ K TY ++RG+ + ++ F+ +L L+ + + E+ FLR A + K + NL L +D + K LK+ L ++E ++ K+ ++T V+ E+ + W +E+LSK K L+++++ ++++ + F+ LG F E+ +DLA++ + +++A P++ G DP G + A E G +++ I++G +G AEK I A K+G WV L+N HLA SW++++E+ I +L HPN+RLFL+ T PV +L+ + EPP G++AN+ R + I K + ++ ++ F + + +AI+QER ++ PLG++ YEF +SD +CAL ++ + DG +IPW AL + G YGG++ +++DQR L + L F+ K + + + G A E T H D ++ LP P G+ +A +L+ IL++Q G S + E+ D A + ++ L + + R + + + E+EV+ LL +R L + + G + + +P +W A P + W++D A R + D K+G W+ G F + ++T T Q+ A+ ++EL Sbjct: 828 EVTNFDALNEVCDELKRKQMMWDSLDE-WEVFTKEWLECQFETLDPEQLNSEV----AKYAKIVNQLEKGLPPNNVVPLLKKKVEFIREKLPVVAFLRNPSLKARHWEMLEEIIGAPLRDKETPLTLAGLIELEVFHYAEQIQDVSGQASGEASLESILKKVEDGWKTAEFVVLPHRDSKDVFILAGTDEIQILLDDSIINISTITSSRYVGPIKSRVDEWQRQLLLFNQTLEEWMTCQRNWLYLESIFS-APDIQRQLPAEAKMFMQVDKSWKDIMRKIYRLPNALRAATQPGLLDTFKNNNALLEQIQKCLEAYLESKRVVFPRFYFLSNDELLEILAQTRNPQAVQPHLRKCFDAIARLEFALAPAEGEQERTFTNDILAMVSPEGEKVSLGK--GLKARGNVEDWLGKVEEAMFQSLRRLTKMAIGEYQSMPRTE----------WVVSGLPSQVVLTVAQLMWCRDLTQCLEGGDHDHLQSVANFEKENFERLNSLACLVRGNLPKIHRCIITALITVDVHARDIVTDMVQEKVETANNFEWQRQLRYYWDLE----LDNCVARMALSQYVYGYEYLGACPRLVITPLTDRCYLCLMGALQLDLGGAPAGPAGTGKTETTKDLAKALAIQCVVFNCSDGLDYKMMGRFFSGLAQSGAWCCFDEFNRIDIEVLSVIAQQLITIRNA----KAAKVPRFMFE--GREIKLIQTCAAFITMNPGYAGRTELPDNLKALFRPIAMMVPNYALIAEVILYSEGFESSRVLARKMTQMYKLCSEQLSQQDHYDFGMRAVKSVLVMAGSLKREN---------------------PHLREDVVLIRALRDSNLPKFLADDAMLFSGILSDLFPGVEIPNHDYGSLQSSIENALKARKL-------QAVPSMVHKVIQLYETMLVRHGVMLVGPTGGGKTTVYTALSDALGSLHEAGESKHNPFYQKVHTTVLNPKSISMGELYGEVNNLTLEWRDGLMALSVRV---AVADDSEDHKWIVCDGPVDALWIENLNTVLDDNKMLCLANSERIKLTPQIHMIFEVQDLKVASPATVSRCGMVYIDSEELKWMPYVQTWMNGIID---KFGE--------DTG-------------------QYIMALFENYVEDGLRFVNKKC----TQAMPQVDISKVTTLSCLLESLLLG--------KGGPDLKMEHSRLTSIVCQTFVFCYLWAVGGNLVENCWDQFDTFVKHQFEENHDAKLPSSGDLWSYYMDYD---SKRLDPWERIVPNFRY-NKEVPFFEMLVPTTDTMRFGYLMEKLLAVKHSVLFTGTTGVGKSVVARGLLDKIQEEAQYVPLYINFSAQTSSTRTQEIIESKLEKKR--KNIIGAPGK--KRVIIFVDDLNMPKLDRYGSQPPIELLRQYQDFGGFYDREKMFWKEIQDAREDRGAMQPFCAPPGG-GRNPVTPRFIRHFSMLCLPSPSEHSLKQIFQAILTGFLVDFPVAVKQVATNIVEAAVEMYGRMSTELLPTPAKSHYIFNLRDLSKCMQGILQC----DSGTVRDQNQIFRLFCHECQRVFHDRLINNEDKDYFNTMLAEMASKQFGVQVEAEYFVKHPILFGDFMKVGVQRADRVYEDLTDVEK--LKGVLQDYLDDYNLSSAKEMKLVFFQDAIEHVTRITRMIRQERGNALLVGVGGTGKQSLTRLACHMCGYRCFQIELSRGYSYDTFHEDLRKLYTIAGVEDKDTVFLFTDTQIVIEEFLEDINNILNSGEVPNLFEKDELEKVLAATRPKAKEAGIPEGNRDEVLQFFINRVRARLHIVLCMSPVGDAFRARCRMFPSIVNCCTIDWFVQWPREALLSVSKTFFTPVDLGSDELKENLSEMCVE--------------------IHMSVTELAEHYYAELRRRYYTTPTSYLELINLYLSMLGEKRSQLTNSRDRIKNGLTKLLETNELVDKLQLELSALEPVLKQKSEDVEALMEKLATDQENADQVR---RVVMEDEAVAKVKAEETQAMAADAQRDLDEALPALQAANRALDSLDRSDISEVRVFTNPPEGVRTVMEAICIVLSKKP-DWASAKQLLGDSNFLKRLTDYDKENISEDVIQKLKV-YINNKDFVPEKVERVSKACKSMCMWVRAMDLYSRVLKDVGPKRQRLATAQAELDATMAMLNDKQRRLKQVEDQIGALQDQFDMSVAEKESLAKNMALTQARMSRAGKLTSALGDEQIRWQESVAQFQVEINNVIGNVFIASACVAYYGAFTSHYRQMLIDRWISRCQELGIPINANFSLIGILGDPFEIRQWNTDGLPRDTVSTENGILVTRGRRWPLMIDPQDQANRWIRNKEMKNGLKIIKLTDGNFLRTLENAIRLGMPVLLEELKETLDPALEPILLKQTFVSGGRLLIRLGDSDVDYDKNFRFYMTTKMANPHYLPEVCIKVTIINFTVTKSGLEDQLLSDVVRLEKPELEEQRNELIVRINADKNQLKVIEDRILKLLFTSEGNILDNEELIKTLQESKVTSGAIKTRLKEAEATEEMINTAREKYRPVAARGSVMYFVIASLSEIDPMYQYSLKYFKQLFNMTIETSEKRSDL---AERLELLLKQTLLATYTNISRGLFEQHKLIFSFMLCIEILRQHGHVS--DAEWNLFLRGA-AGMDKERPTKPEIGWLAESTWNLCCDL-EDHLPCFKGLKREIVAIPILVTLGRLEIRLNPEAWEGCMKEPLHFTEEVS-ENEIQGHW-------NERLSKFQK----LVLVKSFMEEKVVFAMTDFVIENLGKAFIEN--PPVDLATLYQ-DMSASTPLVFVLSTGSDPMGAFQRFAREMGYSERVHAISLGQGQG-PIAEKLIEEAVKSGDWVFLQNCHLAASWMLAMEEIIKALSEPNAVIHPNYRLFLSSMPTRNFPVTVLQNSVKVTNEPPKGLRANIRRAFTEITPAFFEKNVLGQNWRKIIFGICFFHAIIQERKKFGPLGWNIHYEFNDSDRECALLNLNLFCQDG-----------RIPWDALIYITGEITYGGRVTDSWDQRCLRTILKRFFSPKTLEPGYLY---STSGIYYASEEKTLQDHKD---YIENLPLNDDPEIFGMHENANLAFQRQETGTLVKTILEVQPRSSGQG---AGTSNDEIVKELADSILAKLPEI-------LDMEGAMESLFTRDEKGRINSLTTVLEQEVDRFNTLLQVIRSSLHTLKKAIAGFVVMSEEMEKIYNSFLNSQVPVLWSDNAYPSLKPLGGWVKDLALRTTFI----DAWIKTG----PPKSFWISGFFFPQGFLTGTLQNHARKYNLPIDEL 3969
BLAST of Cytoplasmic dynein 1 heavy chain 1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006497.1 (pep scaffold:Pmarinus_7.0:GL476875:373:73185:-1 gene:ENSPMAG00000005847.1 transcript:ENSPMAT00000006497.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 918.687 bits (2373), Expect = 0.000e+0 Identity = 642/2306 (27.84%), Postives = 1131/2306 (49.05%), Query Frame = 3 Query: 3885 NWEKDKPIAGDLTPEEAVNIIQILEGKFNRLKEERENVQKAKEALELTEIGVKPISE----EKVTNALSELHDLKNVWNELKSIWEKIRDMKETPWLSVQPRKLRQDIENLTAQLKELPNSFKQYASFEHVRTLLKMYMKVNASIVELKSEAIKERHWRMLMRKLNVSWSL--NELQLGKVWDIDLVKNEEIIREVLAIAQGEKALEEYLRQITEVWKNYVLELTNYQSKSKIIKGWDDLFNKV---KEHINNVTSMKASPYFKQFEEEATAWEDRLNKINALFDVWIDVQRRWIYLDGIFAGSADIKVLLPVESQRFQSVSTEFLGLMKKVQKSP-LVTDVLNIANVQRQLERLADLLGKIQKSLGEYLERQRSSFPRFYFVGDEDLLEIIGNSXXXXXXXXXXXXMFAGVHSIILSE-DEKVILGMMSKEGEELRFISPVSIIE--HPRINDWLTAMEKEMRVSLAKYLNVAVKEISGWRTESNIDKDKFMVWLDKYQAQIVVLAAQITWSEAVEASLASGVSLESTMTVVHST----LNMLADTVLYEQPPVRRRKLEHLIIEYVHQRDVLRALHNDGVSSNKNFDWMSQMRFYFDPKQTDPLHQLSIHVANAKFHYGFEYLGVCDRLVQTPLTDRCYLTMTQALEARLGGSPFGPAGTGKTESVKSLGNQLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLSAVSQQIQGIQEALRELMVSKKDSINVELLGKQVHVNPDMAIFITMNPGYAGRSNLPDNLKKLFRSLAMTQPDRQLIAQVMLYSQGFRTAEVLAGKVVPFFKLCDEQLSPQSHYDFGLRALKSVLVSAGNVKRDRIKQEKEKIVARGEEINETAIAEQLPEQEILIQSVMETMVPKLIADDIPLLYSLLTDVFPGVEYRQAEMKRLREELRKVSENKFLVYSDEPNTAGYLWVEKVLQLYQITTIHHGLMMVGPSGSGKTMACRVLLQALENIDGIEGVAH---IIDPKSISKDSLYGYMDPNTREWTDGLFTHILRRIIDSVRGESNKRQWIVFDGDVDPEWVENLNSVLDDNKLLTLPNGERLAIPPNVRIMFEVQDLKYATLATVSRCGMVWFSEEVLTTGMILTHFLNELKKVQVMEGEEDFSVNQGDTGADADSKISSSPIIQLQTQVSSILAPFFTEDGLIAKCLDYS-TTLEHIMDFTRLRALTSLFSMIKQSIRNMIEYNQSHSDFPLNNEQIENYVAKSLISSVVWSMSGDSKLKVREQLSQYIK-NISTVDLPTVGGIKNIIDFEVNIQGTWVAWSNKVPQIEVETHKITA-TDVVVPTMDTVRHEALLYTWLAEHRPVLLCGPPGSGKTMTLFSALRCLPDMEV---VGLNFSSATTPELMLKTFDQYCEYRKTPNGIVLAPQQLNKWLIFFCDEINLPDMDKYGTQRVISFLRQMVEHHGFYRI-TDMQWVSFERIQFVGACNPPTDPGRKPLSHRFLRHVPVVYVDYPGETSLKQIYSTFNRAMLRMLPSLRGYADTLTNAMVEFFLKTQERFTH---DMQP-----HYIYSPREMTRWVRGIHEALKPLESLSVEGLVRIWAHEALRLFQDRLVEEDERHWTDDNINEVALKHFPNINKEEALKRPILYSNWLSKDYSAVTQEELRDY----------------VKARLKVF---YEEEL---DVPLVLFNQVLDHVLRIDRVFRQPQGHLLLIGVSGAGKTTLSRFVSWINGLSVFQVKVHNKYTAEDFDEDLRNVLRRSGCKGEKITFIMDESNVMDSSFLERMNTLLANGEVPGLFEGDELTTLMTQC-----KEGAIREGLMIDSQEELYKWFTQQICRNLHVVFTMNPSADGLKDKASTSPALFNRCVLNWFGDWSLEAYFQVGKEFTNRLDLERTDYKVPDTLPCIAEGLLPQNPIYRDVVVNALVFVHQTMHQANVRVQKRGGRTAAITPRHYLDLIAHYMKLSAEKRADLEEQQLHLNNGLKKIEQTVDQVEVMQRSLTKKRQELENMNEAANAKLKQMVQDQQEAEQKKTTGQALKEELAKQEQFVNEKQKTVKQELDQVEPTVNEAKQAVQNIRKKDIQEIKAMKNPPNAVKMAVESICLLLGEKTTD--------------WQSILKVIIKDTFVTSILNFNTDDVSDNTRETMKKKYLSNPDYNFEKVNKASNACG---PMVKWVLAQISYADILKRVEPLRNEL----TELSDA-AEQNRKKSQETEDLIAQLEKSIAKYTEEYATLISQAQTIKSDLASVESKVGRSVALLGSLSSER 10550 +++ P + P+EA + +Q+ + +F+ L + +E L P+++ +++ L+ L L ++N ++ E + E W + K+ ++ + + ++LP + K++ +FE ++ + + + + + ++A+ RHW + ++ + + L + + L+ ++ I ++ A E+ ++ L+ + W + ++S+ +++ D KV ++ + + S+ ++ Y F+ W +L+ + + W+ VQ WIYL+ +F G DI LP E++RFQ++ + +M++ + P +V + + + L L + L QKSL YLE++R FPRF+FV D LLEI+G + D +Q H +F V+ + E + + IL + S+EGE + + PV + WL ++ +R ++ + +++ + + +F + AQ+ +LA Q+ W+ E +L + + M + LN L D + R K E LI +VHQ+D+ L + S +F+W+ Q RFYF ++TD + I + + FHY EYLG DRLV TPLTDRCY+T++QAL +GG+P GPAGTGKTE+ K +G LG++V+VFNC + D++ +GRI+ GL Q GAWGCFDEFNR+E +LS +QQI + + + K + V G V ++ + IF+TMNPGYAGR LP+NLK FR++AM PDR +I +V L S GFR ++L+ K +KLC+EQLS Q HYDFGLR + SVL + G VKR ++ PE+ ++++ + + + KL+ +D PL SL+ D+FPG+ +A L E + ++ LV+ WV K++QLY+ + HG+M +GPSG+GKT +L++A+ + G H ++PK+I+ ++G +D T +WTDG+F+ + R+ + + +GE WI+ DG VD W+ENLNSVLDDNK LTL NG+R+ + PN +++FE ++ A+ ATVSR GMV+ S VL I+ +L QG L T+ + +L + T D + +++ T + MD + ++K + E HS ++ + L+ S++WS+ +L+ R ++ +++ + S +DLP +I ++ V G W W+ +VP+ + + ++VP +D VR + L+ + + + VLL G G+ KT+ + + D E+ LNFSSATTP + +T + Y + R G P K IF D+IN+P ++++G Q +RQ++E++GFY + ++ + +QFV A P GR + R R + P S+ +I+ TF P RG+ + + V T+ + M P HYI++ R+++R +G+ + S + L+ ++ HE +R+ DR + ++ W + ++++ L +++ + + +++ +D T EE D + RL+ F Y E + ++ LV F + H+++I R+ R P+G+ LL+GV G+GK +L+R S+I G S FQ+ + Y + EDL+ + R++G +G+ +TFI ++ + D +FLE MN +LA+GEV LF DE+ + + KE R + E LY +F ++ NLHVV +P + + +A PAL + C ++WF W +A V F +Y+V T P + G++ +++D+V + V +R R +TP+ YL I Y + +EK +++ + GL K+++ V + R L K +EL + A+ L ++ Q AE K Q +K++ + + +++L+ +P + EA+ A+Q I+ DI ++ + PP+ + M + LLL + D W K++ F+ S+L F+ D +++ + + Y+ DYN E A N CG + W A +++ I K V PL+ L + L+ A E +R ++Q E ++ + Y T + + Q + D + K+ + AL+ L E+ Sbjct: 1318 DYDTQGPGEAGIAPQEASDRLQMCQMQFDDLWRKFTTYSGGEELFGL------PVTDYPELQRIRRELALLQKLYGLYN---TVIESVDGYYEILWSDLDIEKINNELLDFQNKCRKLPKALKEWQAFEDLKKKIDNFNETCPLLEMMANKAMMSRHWERITNVTGHTFDIESDHFALKNIMEAPLLTFKDDIEDICISATKERDIDAKLKAVVSEWSSQCFTFAPFKSRGELLLKGSDTAEKVALMEDSLMVLASLMSNRYNVPFKPTIQQWVQKLSNTTEIIENWMMVQNLWIYLEAVFVG-GDIAKQLPQEAKRFQNIDKSWQKIMQRAHEIPGIVVCCVGDETLAQLLPHLLEQLEMCQKSLTGYLEKKRLVFPRFFFVSDPALLEILGQASDPHTIQAHLLGLFDNVNQVGFHEKNYEQILSIESQEGESVTLVEPVMAQRGWQGNVETWLGSLLTGVRSTV----HAVIRQAAAIIEDGAFKLHEFQT---SFPAQVGLLA-QMIWTRDSEVALNNAKNDRKIMPATNQKFLDLLNELIDMTTRDLTKRERVKYETLITIHVHQKDIFDDLVRMNIKSTADFEWLKQSRFYF-VEETD---KCLIQITDVDFHYCNEYLGCTDRLVITPLTDRCYITLSQALGMSMGGAPAGPAGTGKTETTKDMGKCLGKYVVVFNCSDQMDYRGLGRIYKGLAQSGAWGCFDEFNRIELPVLSVAAQQIYIVLQCKK-----NKRTQFVFTDGDIVEMDREFGIFLTMNPGYAGRQELPENLKIQFRTVAMMVPDRAIIMRVKLASAGFRDNQILSRKFYTLYKLCEEQLSKQVHYDFGLRNILSVLRTLGAVKRSNPEE---------------------PEKTVVMRVLRDMNLSKLVDEDEPLFMSLINDLFPGITLDKAGYPELEEAILAQTKAAGLVHHPP-------WVLKIIQLYETQRVRHGMMALGPSGAGKTCCIHMLMKAMTDC----GEPHREMRMNPKAITAPQMFGTLDVATNDWTDGIFSTLWRKTLKAKKGE---HIWILLDGPVDAIWIENLNSVLDDNKTLTLANGDRIPMAPNCKVVFEPHNIDNASPATVSRNGMVFMSSSVLDWRPIVQAWL------------------QG-----------------LPTEQAQVL--WSTMDSVFQDLINFVFTAVNPKMDILECMYIKQAIELLKGLLPEADERRLEHS-----------HLQRLLVFSLMWSVGALLELEDRARMEAFLRAHPSHLDLPGSANDDSIFEYVVGDSGGWEHWNTRVPEFAYPRDTVPEYSAILVPNVDNVRTDFLMQCIMKQEKAVLLIGEQGTAKTVMIKGYMNKY-DAELHLTKSLNFSSATTPNMFQRTVESYVDKRM---GTTYGPPAGRKMTIFI-DDINMPIINEWGDQITNEIVRQLMENNGFYNLEKPGEFTTIVDVQFVAAMIHPGG-GRNDIPQRLKRQFCIFNCTLPSNASIDKIFRTFAEG--HFCPE-RGFPEEVNQLAVALVPTTRRLWQATKVKMLPTPAKFHYIFNLRDLSRIWQGML-IMNSEVCRSSDMLLALFGHECVRVIADRFTAQQDKDWFNGTMSKIMLDDH-GTAAAASMEAEVYFVDFM-RDAPEPTGEEPDDADLEAPKVYEPIPSFPQLAERLQAFLVQYNESVRGANMDLVFFADAMVHLIKISRIIRTPRGNALLVGVGGSGKQSLTRLASFIAGYSSFQITLSRTYNMSNLMEDLKQLYRKTGQQGKGVTFIFTDNEIKDEAFLEYMNNVLASGEVSNLFARDEIDEITQELIPVLKKEHPRRP----PTNENLYDYFLSRVRANLHVVLCFSPVGEKFRARALKFPALISGCTMDWFQSWPRDALTAVAGHFL-------AEYRVECT-PEVKRGVVDAMAVFQDMVA-----------ERCVEYFERFRRQTYVTPKSYLSFIGGYKSIYSEKLSNVALLSERMRTGLSKLQEAEKSVSQLSRELEVKEKELAVASRRADEVLCEVTSKAQAAESVKQQVQKVKDKAQAIVDEIAADKAVAEKKLEAAKPALEEAEAALQTIKPADIGTVRKLSKPPHLI-MRIMDCVLLLFRRRVDTVVPEPERPCMRPSWSEAQKLMNFAGFLNSLLTFSKDTINEEMVDLL-MPYMEMEDYNLE---TARNVCGNVAGLCSWTKAMVTFFGINKEVLPLKANLIIQESRLAVAQGELDRAQAQLDEK-----QRELDAVQAMYDTAVREKQILVDDAEACRRKMNNATALIDGLGGEK 3468
BLAST of Cytoplasmic dynein 1 heavy chain 1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001140.1 (pep scaffold:Pmarinus_7.0:GL478666:370:47701:-1 gene:ENSPMAG00000001005.1 transcript:ENSPMAT00000001140.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 916.376 bits (2367), Expect = 0.000e+0 Identity = 680/2286 (29.75%), Postives = 1112/2286 (48.64%), Query Frame = 3 Query: 4149 ETPWLSVQPRKLRQDIENLTAQLKELPNSFKQY-----------ASFEHVRTLLKMYMKVNASIVELKSEAIKERHWRMLMRKLNVSWSLNE-LQLGKVWDIDLVKNEEIIREVLAIAQGEKALEEYLRQITEVWKNYVLELTNYQ-SKSKIIKGWDDLFNKVKEHINNVTSMKASPYFKQFEEEATAWEDRLNKINALFDVWIDVQRRWIYLDGIFAGSADIKVLLPVESQRFQSVSTEFLGLMKKVQKSPLVTDVLNIANVQRQLERL---ADLLGKIQKSLGEYLERQRSSFPRFYFVGDEDLLEIIGNSXXXXXXXXXXXXMFAGVHSIILSEDEKVILGMMSKEGEELRFISPVSIIE-HPRINDWLTAMEKEMRVSLAKYLNVAVKEI-SGWRTESNIDKDKFMVWLDKYQAQIVVLAAQITWSEAVEASLASGVS-LESTMTVVHSTLNMLADTVLYEQPPVRRRKLEHLIIEYVHQRDVLRALHNDGVSSNKNFDWMSQMRFYFDPKQTDPLHQLSIHVANAKFHYGFEYLGVCDRLVQTPLTDRCYLTMTQALEARLGGSPFGPAGTGKTESVKSLGNQLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLSAVSQQIQGIQEALRELMVSKKDSINVELLGKQVHVNPDMAIFITMNPGYAGRSNLPDNLKKLFRSLAMTQPDRQLIAQVMLYSQGFRTAEVLAGKVVPFFKLCDEQLSPQSHYDFGLRALKSVLVSAGNVKRDRIKQEKEKIVARGEEINETAIAEQLPEQEILIQSVMETMVPKLIADDIPLLYSLLTDVFPGVEYRQAEMKRLREELRKVSENKFLVYSDEPNTAGYLWVEKVLQLYQITTIHHGLMMVGPSGSGKTMACRVLLQALENIDGIEGVAH------IIDPKSISKDSLYGYMDPNTREWTDGLFTHILRRIIDSVRGESNKRQWIVFDGDVDPEWVENLNSVLDDNKLLTLPNGERLAIPPNVRIMFEVQDLKYATLATVSRCGMVWFSEEVLTTGMILTHFLNELKKVQVMEGEEDFSVNQGDTGADADSKISSSPIIQLQTQVSSILAPFFTEDGLIAKCLDY-STTLEHIMDFTRLRALTSLFSMIKQSIRNMIEYNQSHSDFPLNNEQIENYVAKSLISSVVWS--------------------MSG--DSKLKVREQLSQYIKNIS---TVDLPTVGGIKNIIDFEVNIQGTWVAWSNKVPQIEVETHKITATDVVVPTMDTVRHEALLYTWLAEHRPVLLCGPPGSGKTMTLFSALRCLPDMEV---VGLNFSSATTPELMLKTFDQYCEYRKTPNGIVLAPQQLNKWLIFFCDEINLPDMDKYGTQRVISFLRQMVEHHGFYRITDMQWVSFERIQFVGACNPPTDPGRKPLSHRFLRHVPVVYVDYPGETSLKQIYSTFNRAMLRMLPSLRGYA---DTLTNAMVEFFLKTQERFTHDMQP-----HYIYSPREMTRWVRGIHEALKPLESLSVEGLVRIWAHEALRLFQDRLVEEDERHWTDDNINEVA-----------LKHFPNINK--EEALKRPILYSNWL-----SKDYSAVTQ-EELRDYVKARLKVFYE-EELDVPLVLFNQVLDHVLRIDRVFRQPQGHLLLIGVSGAGKTTLSRFVSWINGLSVFQVKVHNKYTAEDFDEDLRNVLRRSGCKGEKITFIMDESNVMDSSFLERMNTLLANGEVPGLFEGD---ELTTLMTQCKEGAIREGLMIDSQEELYKWFTQQICRNLHVVFTMNPSADGLKDKASTSPALFNRCVLNWFGDWSLEAYFQVGKEFTNRLDLERTDYKVPDTLPCIAEGLLPQNPIYRDVVVNALVFVHQTMHQANVRVQKRGGRTAAITPRHYLDLIAHYMKLSAEKRADLEEQQLHLNNGLKKIEQTVDQVEVMQRSLTKKRQELENMNEAANAKLKQMVQDQQEAEQKKTTGQALKEELAKQEQFVNEK---QKTVKQELD----QVEPTVNEAKQAVQNIRKKDIQEIKAMKNPPNAVKMAVESICLLLGEKTTD--------------WQSILKVIIKDTFVTSILNFNTDDVSDNTRETMKKKYLSNPDYNFEKVNKASNACGPMVKWVLAQISYADILKRVEPLRNEL----TELSDAAEQNRKKSQ---ETEDLIAQLEKSIAKYTEEYATLISQAQTIKSDLASVESKVGRSVALLGSLSSERTRWDSGSETFKAQMATINGDCLLSSAFMAYGGYFDQHMR 10667 E P V P + QD+ N L +L S + ++ E RT L M A + L + ++ RHW L + E + L K +++L ++ A E +LE+ L ++ W L Y+ S + I+ DD+ + +HI +M+ SP+ K FE + WE +L + + D W+ VQ W+YL+ IF+ S DI +P E +RF +V + L+K+ T VL + ++ + LERL +LL I K L +YLE++R FPRF+F+ +++LLEI+ +KD ++Q H KK F G+ + +E I M S EGE ++ I +S + ++ WL +E M S+ + A++ S R E W+ + Q V+ +Q W+ V ++ G LE + + ++ + V + R L L++ VH RDVL AL G++ + +F W+SQ+R+Y++ L + NA YG+EYLG RLV TPLTDRCY T+ AL LGG+P GPAGTGKTE+ K L + + +VFNC + D+ A+G+ F GL GAW CFDEFNR++ +LS V+QQI IQ + + D++ E G ++ +NP A+FITMNPGYAGRS LPDNLK LFR++AM PD +IA++MLYS GF +A L+ K+V ++LC EQLS Q HYD+G+RA+KSVL +AGN+K + E E I ++++S+++ +PK +A D+PL + +D+FPGV+ + + L E +++ E L +D + EK+LQ+Y++ + HG M+VG GKT A RVL AL +I +A +++PK+I+ LYG D + EW+DG+ R S S R+W+VFDG VD W+EN+N+VLDDNK L L +GE + + ++FE DL+ A+ ATVSRCGM++ +L +LT +LN A S+P L I A F + L+ CL + + + + + + SL +++ M +++ +++ + ++ + S+VWS MSG + R LS+ ++ + +V P G + F +G W W+ + + D++VPT+DT+R AL+ + +PVL GP G+GK++ + + L D + +NFS+ TT + R+ V P Q K ++ F D++N+P ++YG Q + LRQ ++H +Y + D + E +Q +GA PP GR ++ RFLRH V ++ E K +++ F+R M + + LT +V+ ++ + T ++ P HY+++ R+ +R ++G+ +L P + R+W HE LR+F DRLV++ +R W I + +H N + E+ R +++ ++ +K Y V+ E LR V+ L+ F + + LVLF ++HV RI R+ +QP+ H LL+GV G+G+ +L+R + + +FQV++ Y ++ EDL+ +LRRS + F+ ++ + SFLE +N LL +GE+P LF D E+ M Q ++ S L F + LHVV M+P D +++ P+L N C ++WF W +A V + LE + CI + H + + + Q R +TP YL+LI+ + L +KR ++ + GL+K+E QV MQ L + +L EA + M ++E+E+ T + +K + E NE+ K +K E D + P + A A+ + ++DI +K MK+PP VK+ +E+I +L G K W +++ F+ S+ +F+ D++ +T++ KY++N +++ +K+ AS A + KWV+A SY + K V P + +L EL+ A R+K + E +D +A L++++ ++ A L +Q D+ + K+ R+ L+G L ER+RW + + + GD L+SS +AY G F R Sbjct: 664 EGPLADVNPDVVEQDVGNYWRGLYKLERSLQASPQALLIQQQLKSNVEAFRTHLPM-----AQV--LCNPGLRGRHWDALSEVVGFPLLTQEQVCLEKFLEMNLESFLSKFNDISDTASKEYSLEKALEKMVREWDEMQFTLIVYRDSGTSILSAVDDIQMLLDDHIVKTQTMRGSPFIKPFESDMKEWERKLLLLQEILDEWLKVQATWLYLEPIFS-SPDIMAQMPEEGRRFTTVDKTWRDLIKQTLTD---THVLAVVSIDKMLERLQKSTELLELILKGLNDYLEKKRLFFPRFFFLSNDELLEILSETKDPTRVQPHLKKCFEGISRVEFTEALD-ITHMKSSEGEVVQLIETISTSKARGQVEKWLLELEAVMIRSVHNVIGEAMEAYPSTPRAE----------WVRAWPGQTVLCVSQAFWTSEVHEAIRGGQQVLERYLAQCNGQIDEVVGLVRGQLSQQSRVTLGALVVLDVHARDVLVALLKGGIAHDSDFQWLSQLRYYWEDGH------LQTRMINAGLPYGYEYLGNTPRLVITPLTDRCYRTLFGALNLHLGGAPEGPAGTGKTETTKDLAKAVAKQCVVFNCSDGLDYIALGKFFKGLLSCGAWACFDEFNRIDLEVLSVVAQQILTIQRGIN----TGSDTLMFE--GTELKLNPTCAVFITMNPGYAGRSELPDNLKALFRTVAMMVPDYAMIAEIMLYSFGFVSARPLSVKIVATYRLCSEQLSSQHHYDYGMRAVKSVLTAAGNLKL-KYPSENEDI--------------------LMLRSIVDVNLPKFLAHDLPLFEGITSDLFPGVKLPKPDYVVLLEAIKENCEKMNLQMTD-------FFAEKILQIYEMMIVRHGFMIVGEPFGGKTCAYRVLAAALGDICEKALMAENKVQITVLNPKAITMGQLYGQFDAISHEWSDGVLAVSYRAFATST---SPDRKWLVFDGPVDAVWIENMNTVLDDNKKLCLMSGEIIQLASTTNLIFEPMDLEVASPATVSRCGMIYMEPHILGWRPLLTSWLN------------------------ARPPPLSAPHKAL------ICALF---ERLVPCCLQFVRKSTKELSPTSDTNLVCSLMNLMDC---QMDDFHDETKIKAMDDRDVSAWIEGIFLFSLVWSVGASCSTHGQVLFDQLLRELMSGPLSADTSKRFHLSENVEPPAEPFSVPFPAAGSVYE-YRFIQEGKGRWELWTEALSLAPPIPRDMNFNDIIVPTLDTIRFTALMEMLVTHQKPVLFVGPTGTGKSVYITNFLLKHLDKNTYKPLTINFSAQTTAAQTQNIIMGKLDRRRKG---VYGPAQ-GKRMVLFVDDVNMPAREEYGAQPPVELLRQWLDHSNWYDLKDCSMIKLENVQILGAMGPPGG-GRNAVTARFLRHFNTVTIN---EFDDKSMFTIFSRIMGWHFTARFAFPTDFSVLTEQLVQSTMEVYKAATQNLLPTPTKSHYLFNLRDFSRVIQGVCLSL-PETCPVAASIQRLWVHEVLRVFYDRLVDDADRTWLVAFIRKTIHTYMKEDFTQLFQHDSNGDGQVEDDDLRSLMFCDFSDSKDDAKRYVEVSDVERLRLVVEGHLEEFNNLSKKPMNLVLFRFAIEHVCRISRILKQPRSHALLVGVGGSGRQSLTRLAAHMADCELFQVEISKGYATNEWREDLKRILRRSTDGEQNGVFLFTDTQIKQESFLEDINNLLNSGEIPNLFAPDEKQEICEKMRQIDRQRDKDKQTDGSPLALLNMFVDRCRDQLHVVLAMSPIGDAFRNRLRKFPSLVNCCTIDWFQSWPGDALQAVATRY-----LEDVEVSEETLASCI----------------DMCKLFHTSTIALSQKFQAEQQRYNYVTPTSYLELISTFKDLLEKKRLEVMRMKRRYEVGLEKLESATSQVAGMQAELAALQPQLL---EAGIQVVNTMAVIERESEEVSRTERVVKAD----EAVANEQAMAAKVIKDECDADLAEALPILRSALAALDTLTQQDITVVKTMKSPPAGVKLVMEAISILKGVKPDRVPDPSGSGRMVEDLWGPAKRLLGDMKFLQSLHDFDKDNIPVAIMKTIRAKYITNLEFDPDKIRNASTAAEGLCKWVIAMESYDKVAKVVAPKKVKLNQAEAELAVAMGSLRRKQEALREVQDKLAGLQQTLEANKQKKADLENQV-----DMCT--KKLDRAEQLIGGLGGERSRWMEAARLLGIRYNDLTGDTLVSSGIVAYLGAFISSFR 2803
BLAST of Cytoplasmic dynein 1 heavy chain 1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001372.1 (pep scaffold:Pmarinus_7.0:GL479430:457:33677:-1 gene:ENSPMAG00000001214.1 transcript:ENSPMAT00000001372.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 843.573 bits (2178), Expect = 0.000e+0 Identity = 625/2181 (28.66%), Postives = 1039/2181 (47.64%), Query Frame = 3 Query: 4446 REVLAIAQGEKALEEYLRQITEVWKNYVLELTNYQSKSKIIKGWDD---LFNKVKEHINNVTSMKASPYFKQFEEEATAWEDRLNKINALFDVWIDVQRRWIYLDGIFAGSADIKVLLPVESQRFQSVSTEFLGLMKKVQK-SPLVTDVLNIANVQRQLERLADLLGKIQKSLGEYLERQRSSFPRFYFVGDEDLLEIIGNSXXXXXXXXXXXXMFAGVHSIILSEDEKV---ILGMMSKEGEELRFISPVSIIEHPRINDWLTAMEKEMRVSLAKYLNVAVKEISGWRTESNIDKDKFMVWLDKYQAQIVVLAAQITWSEAVEASLASG----VSLESTMTVVHSTLNMLADTVLYEQPPVRRRKLEHLIIEYVHQRDVLRALHNDGVSSNKNFDWMSQMRFYFDPKQTDPLHQLSIHVANAKFHYGFEYLGVCDRLVQTPLTDRCYLTMTQALEARLGGSPFGPAGTGKTESVKSLGNQLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLSAVSQQIQGIQEALRELMVSKKDSINVELLGKQVHVNPDMAIFITMNPGYAGRSNLPDNLKKLFRSLAMTQPDRQLIAQVMLYSQGFRTAEVLAGKVVPFFKLCDEQLSPQSHYDFGLRALKSVLVSAGNVKRDRIKQEKEKIVARGEEINETAIAEQLPEQEILIQSVMETMVPKLIADDIPLLYSLLTDVFPGVEYRQAEMKRLREEL-RKVSENKFLVYSDEPNTAGYLWVEKVLQLYQITTIHHGLMMVGPSGSGKTMACRVLLQALENIDGIEGVAH---IIDPKSISKDSLYGYMDPNTREWTDGLFTHILRRIIDSVRGESNKRQWIVFDGDVDPEWVENLNSVLDDNKLLTLPNGERLAIPPNVRIMFEVQDLKYATLATVSRCGMVWFSEEVLTTGMILTHFLNELKKVQVMEGEEDFSVNQGDTGADADSKISSSPIIQLQTQVSSILAPFFTEDGLIAKCLDYSTTLEHIMDFTRLRALTSLFSMIKQSIRNMIEYNQSHSDFPLNNEQIENYVAKSLISSVVWSMSGDSKLKVREQLSQYIKNIST--VDLPTVG--GIKNIIDFEVNIQGTWVAWSNKVPQIEVET-HKITATDVVVPTMDTVRHEALLYTWLAEHRPVLLCGPPGSGKTMTLFSAL-RCLPDMEVV-GLNFSSATTPELMLKTFDQYCEYRKTPNGIVLAPQQLNKWLIFFCDEINLPDMDKYGTQRVISFLRQMVEHHGFYRITD-MQWVSFERIQFVGACNPPTDPGRKPLSHRFLRHVPVVYVDYPGETSLKQIYSTFN----RAMLRMLPSLRGYADTLTNAMVEFFLKTQ-ERFTHDMQPHYIYSPREMTRWVRGIHEALKPLESLSVEGLVRIWAHEALRLFQDRLVEEDERHWTDDNINEVA-----------------------LKHFPNINKEEA----LKRPILYSNWLSKDYSAVTQEELRDYVKARLKVFYEE--ELDVPLVLFNQVLDHVLRIDRVFRQPQGHLLLIGVSGAGKTTLSRFVSWINGLSV-----------------FQVKVHNKYTAEDFDEDLRNVLRRSGCKGEKITFIMDESNVMDSSFLERMNTLLANGEVPGLFEGDELTTLMTQC-----KEGAIREGLMIDSQEELYKWFTQQICRNLHVVFTMNPSADGLKDKASTSPALFNRCVLNWFGDWSLEAYFQVGKEFTNRLDLERTDYKVPDTLPCIAEGLLPQNPIYRDVVVNALVFVHQTMHQANVRVQKRGGRTAAITPRHYLDLIAHYMKLSAEKRADLEEQQLHLNNGLKKIEQTVDQVEVMQRSLTKKRQELENMNEAANAKLKQMVQDQQEAEQKKTTGQALKEELAKQEQFVNEKQKTVKQELDQVEPTVNEAKQAVQNIRKKDIQEIKAMKNPPNAVKMAVESICLLL-------------GEKTTDWQSILKVIIKDTFVTSILNFNTDDVSDNTRETMKKKYLSNPDYNFEKVNKASNACGPMVKWVLAQISYADILKRVEPLRNELT----ELSDAAEQNRKKSQETEDLIAQLEKSIAKYTEEYATLISQAQTIKSDLASVESKVGRSVALLGSLSSERTRWDSGSETFKAQMATINGDCLLSSAFMAYGGYFDQHMRTSLFNTWCHHL 10700 +++ A E+ +E L+Q+ W N++++ +++ D+ + +++ + + S+ ++ Y F+ + W L+ + + W+ VQ W+YL+ +F G DI LP E++RF ++ ++ +M + + + +V + + + L L + L QKSL YLE++R FPRF+FV D LLEI+G + D +Q H +F + ++ E KV IL + S+EGE ++ PV + + WL A+ KE + SL + A + +S +F LD Y AQ+ +L Q+ W+ E +LA+ ++ T LN L + V R K E LI +VHQRD+ L + S +F+W+ Q RFYF + + +L + + + F Y E+LG DRLV TPLTDRCY+T+ QAL +GG+P GPAGTGKTE+ K +G LG++V+VFNC + DF+ +GRIF GL Q G+WGCFDEFNR++ +LS +QQI + +E + S G V +NP+ IF+TMNPGYAGR LP+NLK FRS+AM PDRQ+I +V L S GF VLA K +KLC+EQLS Q ++ +G+ V+ S K A G+ T+ QL I+S + K+I +D PL SL+ D+FPG+ +A +L + R+V + ++++ W KV+QLY+ + HG+M +GPSG+GKT L++A+ G H ++PK+I+ ++G +D T +WTDG+F+ + R+ + +GE WIV DG VD W+ENLNSVLDDNK LTL NG+R+ + PN +++FE ++ A+ ATVSR GMV+ S VL IL +L + SP Q + + S+ A F L+ H + F ++ L + +I QS+ NM++ D E ++ + + +++WS+ +L R ++ ++++ + +DLP V G ++ D+ V G WV WS++V + H ++VP +D VR + L++ + + VLL G G+ KT+ L L + P+ + LNFSSATTP + +T + Y + + G P K L F D+IN+P ++++G Q +RQ++E GFY + ++ + +QFV A P GR + R R + + P S+ +I+ A +R A L A + T+ + + HY+++ R+++R +G+ + S S E L+R++ HE R+ DR ++ W ++ + VA L+ P +E P +Y S D ELRD + L+ + E + LV F + H+++ I V G TL F +G S+ F + Y+ + EDL+ + R +G +G+ ITF+ ++ + D +FLE MN +L++GEV LF DE+ ++++ K+ R +QE L+++F ++ NLHVV +P + + +A PAL + C ++WF W +A V + F + ++ T + + C+ ++D V Q R R+ +TP+ YL + Y + EK +++ + GL+K+++ + V + L K +EL+ NE A+ LK++ Q AE+ K Q +KE + ++ + +++L +P + EA+ A+Q I++ DI ++ + PP+ + ++ + LL G T WQ LK++ F+ S+ F D +++ E + Y PDYN + K + W A + I K V PL++ L L+ A + E + A+L+ A Y + + + Q + D K+ + L+ L+ E+ RW + S+ F AQ+ + GD L+++AF++Y G F+Q R L W L Sbjct: 1 QDICISAVKERDIEFKLKQVVAEWDGKTFTFGNFKTRGELLLRGDNTTEIIATMEDSLMVLGSLMSNRYNAPFKSQIQKWVSNLSNTTDIIENWMTVQNLWVYLEAVFVG-GDIAKQLPKEAKRFSNIDKSWVKIMTRAHEMNNVVQCCVGDETMGQLLPHLLEQLELCQKSLTGYLEKKRLLFPRFFFVSDPALLEILGQASDSHTIQAHLLNVFDNIKTVEFHE--KVYDRILAVCSREGETVQLDKPV--MADGNVEVWLNALLKESQQSLHGVIRSAALAVQ----DSAFSLIEF---LDSYPAQVGLLGIQLLWTRDSEEALANARYNRKAMPQTNQAFLVLLNRLISMTTQDLSAVERIKYETLITIHVHQRDIFDDLCRMHIKSPTDFEWLKQCRFYFK----EDVDKLIVWITDVSFIYQNEFLGCTDRLVITPLTDRCYITLAQALGMSMGGAPAGPAGTGKTETTKDMGRCLGKYVVVFNCSDQMDFRGLGRIFKGLAQSGSWGCFDEFNRIDLPVLSVAAQQIAIVLTCKKE-----RRSQFTFTDGDLVEMNPEFGIFLTMNPGYAGRQELPENLKINFRSVAMMVPDRQIIIRVKLASCGFLDNIVLARKFYTLYKLCEEQLSKQVYWVYGIL---EVMYSLKTCK------------AMGKA--HTSSTAQL----FCIRSYRRVSMMKVIDEDEPLFLSLIDDLFPGIALDKAGYPQLEAAINRQVEQAGLVIHAP--------WKLKVIQLYETQCVRHGMMALGPSGAGKTTCIHTLMRAMTEC----GSPHREMRMNPKAITAPQMFGRLDVATNDWTDGIFSTLWRKTTRAKKGE---HIWIVLDGPVDAIWIENLNSVLDDNKTLTLANGDRIPMAPNCKVVFEPHNIDNASPATVSRNGMVFMSSSVLDWSPILEGWLKQ-----------------------------RSP--QERETLRSLYAKSF---------LELYRYAAHSLSF-KMDTLEAF--VIVQSL-NMLQGLIPSKDH--GGEVTPEHLGRLYVFALMWSVCAYLELDDRRRMELWLRSHESMRLDLPAVSPHGEDSMFDYMVGADGQWVHWSSRVEEYAYPGDHTPEYNSILVPNVDNVRTDFLIHNIAKQGKSVLLMGEQGTAKTVMLKGYLSKYDPETHLAKNLNFSSATTPLMFQRTIESYVDKKM---GTTYGPPA-GKKLTVFIDDINMPIINEWGDQVTNEIVRQLMEQRGFYNLEKPGEFTNIVDVQFVAAMIHPGG-GRNDIPQRLKRQLSIFNCTLPSNASIDKIFGVIGTGHYSAARGFTEGVRALAAQLVPATRRLWQLTKIKMLPTPAKFHYVFNLRDLSRIWQGLLNTTADVVS-SPELLLRLFKHECERVIADRFTCAEDTDWFEERLAAVASEELGAAAGEALAVGERAFFVDFLRDAPEATGDEPEDADFDMPKIYEPIASYD-------ELRDRLNFFLQQYNESVRGARMDLVFFTDAMLHLVK-------------FIPVLGVTNLTLMTF----DGHSLQDWAVPGVVRHDAQHIQFDLTFSTSYSTSNLLEDLKVLYRVAGQQGKGITFLFTDNEIKDEAFLEYMNNVLSSGEVSNLFARDEMDEILSELAPVMKKQHPRRP----PTQENLHEFFMTRVRLNLHVVLCFSPVGERFRTRALRFPALISGCTMDWFSRWPKDALVAVSEHFLSSYTMDCTVEVKQEVVACMGS--------FQDGVAEKCTDYFQ-----------RFRRSTHVTPKSYLSFVQGYKTVYKEKHTEVQTLANRMQMGLQKLKEASESVAGLSVELEMKEKELQVANEKADKVLKEVTVKAQAAEKVKMEVQKVKETAERIVDSISVDKAVAEKKLVAAKPALEEAEAALQTIKQSDIATVRTLGRPPHLIMRIMDCVLLLFQRRVNPVRMDPERGCVTPSWQESLKLMTAGNFLGSLKQFPKDTITEEMVELL-HPYFDMPDYNIDTARKVCGNVAGLCSWTKAMAYFFGINKEVLPLKSNLVVQQGRLNIAMGDLQSAQAELDAKQAELDLVQAGYEKA----LREKQELMDDAERCRRKMQTASGLISGLAGEKERWTNMSKEFAAQIKRLVGDVLMATAFLSYAGPFNQEFRNLLLGEWQREL 2020
BLAST of Cytoplasmic dynein 1 heavy chain 1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001370.1 (pep scaffold:Pmarinus_7.0:GL479430:457:33677:-1 gene:ENSPMAG00000001214.1 transcript:ENSPMAT00000001370.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 843.573 bits (2178), Expect = 0.000e+0 Identity = 623/2168 (28.74%), Postives = 1038/2168 (47.88%), Query Frame = 3 Query: 4446 REVLAIAQGEKALEEYLRQITEVWKNYVLELTNYQSKSKIIKGWDD---LFNKVKEHINNVTSMKASPYFKQFEEEATAWEDRLNKINALFDVWIDVQRRWIYLDGIFAGSADIKVLLPVESQRFQSVSTEFLGLMKKVQK-SPLVTDVLNIANVQRQLERLADLLGKIQKSLGEYLERQRSSFPRFYFVGDEDLLEIIGNSXXXXXXXXXXXXMFAGVHSIILSEDEKV---ILGMMSKEGEELRFISPVSIIEHPRINDWLTAMEKEMRVSLAKYLNVAVKEISGWRTESNIDKDKFMVWLDKYQAQIVVLAAQITWSEAVEASLASG----VSLESTMTVVHSTLNMLADTVLYEQPPVRRRKLEHLIIEYVHQRDVLRALHNDGVSSNKNFDWMSQMRFYFDPKQTDPLHQLSIHVANAKFHYGFEYLGVCDRLVQTPLTDRCYLTMTQALEARLGGSPFGPAGTGKTESVKSLGNQLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLSAVSQQIQGIQEALRELMVSKKDSINVELLGKQVHVNPDMAIFITMNPGYAGRSNLPDNLKKLFRSLAMTQPDRQLIAQVMLYSQGFRTAEVLAGKVVPFFKLCDEQLSPQSHYDFGLRALKSVLVSAGNVKRDRIKQEKEKIVARGEEINETAIAEQLPEQEILIQSVMETMVPKLIADDIPLLYSLLTDVFPGVEYRQAEMKRLREEL-RKVSENKFLVYSDEPNTAGYLWVEKVLQLYQITTIHHGLMMVGPSGSGKTMACRVLLQALENIDGIEGVAHIIDPKSISKDSLYGYMDPNTREWTDGLFTHILRRIIDSVRGESNKRQWIVFDGDVDPEWVENLNSVLDDNKLLTLPNGERLAIPPNVRIMFEVQDLKYATLATVSRCGMVWFSEEVLTTGMILTHFLNELKKVQVMEGEEDFSVNQGDTGADADSKISSSPIIQLQTQVSSILAPFFTEDGLIAKCLDYSTTLEHIMDFTRLRALTSLFSMIKQSIRNMIEYNQSHSDFPLNNEQIENYVAKSLISSVVWSMSGDSKLKVREQLSQYIKNIST--VDLPTVG--GIKNIIDFEVNIQGTWVAWSNKVPQIEVET-HKITATDVVVPTMDTVRHEALLYTWLAEHRPVLLCGPPGSGKTMTLFSAL-RCLPDMEVV-GLNFSSATTPELMLKTFDQYCEYRKTPNGIVLAPQQLNKWLIFFCDEINLPDMDKYGTQRVISFLRQMVEHHGFYRITD-MQWVSFERIQFVGACNPPTDPGRKPLSHRFLRHVPVVYVDYPGETSLKQIYSTFN----RAMLRMLPSLRGYADTLTNAMVEFFLKTQ-ERFTHDMQPHYIYSPREMTRWVRGIHEALKPLESLSVEGLVRIWAHEALRLFQDRLVEEDERHWTDDNINEVA-----------------------LKHFPNINKEEA----LKRPILYSNWLSKDYSAVTQEELRDYVKARLKVFYEE--ELDVPLVLFNQVLDHVLRIDRVFRQPQ-------GHLLLIGVSGAGKTTLSRFVSWINGLSVFQVKVHNKYTAEDFDEDLRNVLRRSGCKGEKITFIMDESNVMDSSFLERMNTLLANGEVPGLFEGDELTTLMTQC-----KEGAIREGLMIDSQEELYKWFTQQICRNLHVVFTMNPSADGLKDKASTSPALFNRCVLNWFGDWSLEAYFQVGKEFTNRLDLERTDYKVPDTLPCIAEGLLPQNPIYRDVVVNALVFVHQTMHQANVRVQKRGGRTAAITPRHYLDLIAHYMKLSAEKRADLEEQQLHLNNGLKKIEQTVDQVEVMQRSLTKKRQELENMNEAANAKLKQMVQDQQEAEQKKTTGQALKEELAKQEQFVNEKQKTVKQELDQVEPTVNEAKQAVQNIRKKDIQEIKAMKNPPNAVKMAVESICLLL-------------GEKTTDWQSILKVIIKDTFVTSILNFNTDDVSDNTRETMKKKYLSNPDYNFEKVNKASNACGPMVKWVLAQISYADILKRVEPLRNELT----ELSDAAEQNRKKSQETEDLIAQLEKSIAKYTEEYATLISQAQTIKSDLASVESKVGRSVALLGSLSSERTRWDSGSETFKAQMATINGDCLLSSAFMAYGGYFDQHMRTSLFNTWCHHL 10700 +++ A E+ +E L+Q+ W N++++ +++ D+ + +++ + + S+ ++ Y F+ + W L+ + + W+ VQ W+YL+ +F G DI LP E++RF ++ ++ +M + + + +V + + + L L + L QKSL YLE++R FPRF+FV D LLEI+G + D +Q H +F + ++ E KV IL + S+EGE ++ PV + + WL A+ KE + SL + A + +S +F LD Y AQ+ +L Q+ W+ E +LA+ ++ T LN L + V R K E LI +VHQRD+ L + S +F+W+ Q RFYF + + +L + + + F Y E+LG DRLV TPLTDRCY+T+ QAL +GG+P GPAGTGKTE+ K +G LG++V+VFNC + DF+ +GRIF GL Q G+WGCFDEFNR++ +LS +QQI + +E + S G V +NP+ IF+TMNPGYAGR LP+NLK FRS+AM PDRQ+I +V L S GF VLA K +KLC+EQLS Q ++ +G+ V+ S K A G+ T+ QL I+S + K+I +D PL SL+ D+FPG+ +A +L + R+V + ++++ W KV+QLY+ + HG+M +GPSG+GKT L++A+ G ++PK+I+ ++G +D T +WTDG+F+ + R+ + +GE WIV DG VD W+ENLNSVLDDNK LTL NG+R+ + PN +++FE ++ A+ ATVSR GMV+ S VL IL +L + SP Q + + S+ A F L+ H + F ++ L + +I QS+ NM++ D E ++ + + +++WS+ +L R ++ ++++ + +DLP V G ++ D+ V G WV WS++V + H ++VP +D VR + L++ + + VLL G G+ KT+ L L + P+ + LNFSSATTP + +T + Y + + G P K L F D+IN+P ++++G Q +RQ++E GFY + ++ + +QFV A P GR + R R + + P S+ +I+ A +R A L A + T+ + + HY+++ R+++R +G+ + S S E L+R++ HE R+ DR ++ W ++ + VA L+ P +E P +Y S D ELRD + L+ + E + LV F + H+++ V GH L +S + +T V L+ Y+ + EDL+ + R +G +G+ ITF+ ++ + D +FLE MN +L++GEV LF DE+ ++++ K+ R +QE L+++F ++ NLHVV +P + + +A PAL + C ++WF W +A V + F + ++ T + + C+ ++D V Q R R+ +TP+ YL + Y + EK +++ + GL+K+++ + V + L K +EL+ NE A+ LK++ Q AE+ K Q +KE + ++ + +++L +P + EA+ A+Q I++ DI ++ + PP+ + ++ + LL G T WQ LK++ F+ S+ F D +++ E + Y PDYN + K + W A + I K V PL++ L L+ A + E + A+L+ A Y + + + Q + D K+ + L+ L+ E+ RW + S+ F AQ+ + GD L+++AF++Y G F+Q R L W L Sbjct: 1 QDICISAVKERDIEFKLKQVVAEWDGKTFTFGNFKTRGELLLRGDNTTEIIATMEDSLMVLGSLMSNRYNAPFKSQIQKWVSNLSNTTDIIENWMTVQNLWVYLEAVFVG-GDIAKQLPKEAKRFSNIDKSWVKIMTRAHEMNNVVQCCVGDETMGQLLPHLLEQLELCQKSLTGYLEKKRLLFPRFFFVSDPALLEILGQASDSHTIQAHLLNVFDNIKTVEFHE--KVYDRILAVCSREGETVQLDKPV--MADGNVEVWLNALLKESQQSLHGVIRSAALAVQ----DSAFSLIEF---LDSYPAQVGLLGIQLLWTRDSEEALANARYNRKAMPQTNQAFLVLLNRLISMTTQDLSAVERIKYETLITIHVHQRDIFDDLCRMHIKSPTDFEWLKQCRFYFK----EDVDKLIVWITDVSFIYQNEFLGCTDRLVITPLTDRCYITLAQALGMSMGGAPAGPAGTGKTETTKDMGRCLGKYVVVFNCSDQMDFRGLGRIFKGLAQSGSWGCFDEFNRIDLPVLSVAAQQIAIVLTCKKE-----RRSQFTFTDGDLVEMNPEFGIFLTMNPGYAGRQELPENLKINFRSVAMMVPDRQIIIRVKLASCGFLDNIVLARKFYTLYKLCEEQLSKQVYWVYGIL---EVMYSLKTCK------------AMGKA--HTSSTAQL----FCIRSYRRVSMMKVIDEDEPLFLSLIDDLFPGIALDKAGYPQLEAAINRQVEQAGLVIHAP--------WKLKVIQLYETQCVRHGMMALGPSGAGKTTCIHTLMRAMTEC-GSPHREMRMNPKAITAPQMFGRLDVATNDWTDGIFSTLWRKTTRAKKGE---HIWIVLDGPVDAIWIENLNSVLDDNKTLTLANGDRIPMAPNCKVVFEPHNIDNASPATVSRNGMVFMSSSVLDWSPILEGWLKQ-----------------------------RSP--QERETLRSLYAKSF---------LELYRYAAHSLSF-KMDTLEAF--VIVQSL-NMLQGLIPSKDH--GGEVTPEHLGRLYVFALMWSVCAYLELDDRRRMELWLRSHESMRLDLPAVSPHGEDSMFDYMVGADGQWVHWSSRVEEYAYPGDHTPEYNSILVPNVDNVRTDFLIHNIAKQGKSVLLMGEQGTAKTVMLKGYLSKYDPETHLAKNLNFSSATTPLMFQRTIESYVDKKM---GTTYGPPA-GKKLTVFIDDINMPIINEWGDQVTNEIVRQLMEQRGFYNLEKPGEFTNIVDVQFVAAMIHPGG-GRNDIPQRLKRQLSIFNCTLPSNASIDKIFGVIGTGHYSAARGFTEGVRALAAQLVPATRRLWQLTKIKMLPTPAKFHYVFNLRDLSRIWQGLLNTTADVVS-SPELLLRLFKHECERVIADRFTCAEDTDWFEERLAAVASEELGAAAGEALAVGERAFFVDFLRDAPEATGDEPEDADFDMPKIYEPIASYD-------ELRDRLNFFLQQYNESVRGARMDLVFFTDAMLHLVKFIPVLGVTNLTLMTFDGHSLQDILSASLRTDSDPAV-----LTPVVTPASRSYSTSNLLEDLKVLYRVAGQQGKGITFLFTDNEIKDEAFLEYMNNVLSSGEVSNLFARDEMDEILSELAPVMKKQHPRRP----PTQENLHEFFMTRVRLNLHVVLCFSPVGERFRTRALRFPALISGCTMDWFSRWPKDALVAVSEHFLSSYTMDCTVEVKQEVVACMGS--------FQDGVAEKCTDYFQ-----------RFRRSTHVTPKSYLSFVQGYKTVYKEKHTEVQTLANRMQMGLQKLKEASESVAGLSVELEMKEKELQVANEKADKVLKEVTVKAQAAEKVKMEVQKVKETAERIVDSISVDKAVAEKKLVAAKPALEEAEAALQTIKQSDIATVRTLGRPPHLIMRIMDCVLLLFQRRVNPVRMDPERGCVTPSWQESLKLMTAGNFLGSLKQFPKDTITEEMVELL-HPYFDMPDYNIDTARKVCGNVAGLCSWTKAMAYFFGINKEVLPLKSNLVVQQGRLNIAMGDLQSAQAELDAKQAELDLVQAGYEKA----LREKQELMDDAERCRRKMQTASGLISGLAGEKERWTNMSKEFAAQIKRLVGDVLMATAFLSYAGPFNQEFRNLLLGEWQREL 2022
BLAST of Cytoplasmic dynein 1 heavy chain 1 vs. Ensembl Yeast
Match: DYN1 (Cytoplasmic heavy chain dynein; microtubule motor protein; member of the AAA+ protein family, required for anaphase spindle elongation; involved in spindle assembly, chromosome movement, and spindle orientation during cell division, targeted to microtubule tips by Pac1p; motility along microtubules inhibited by She1p [Source:SGD;Acc:S000001762]) HSP 1 Score: 1827.37 bits (4732), Expect = 0.000e+0 Identity = 1140/3828 (29.78%), Postives = 1992/3828 (52.04%), Query Frame = 3 Query: 375 EVNFESNKSQTSIFIKNNQVIEADKTISSQLQVLSYCDGP-PFETMHSLVCYGLLPYFXXXXXXXXXXXXXXXXXMVPSVEKKIAELEIGLLHLQQNIEIPEITLTPHPYVAHIIQEKLLQNKEARVSDF-----EDKFEDTQFLNQLQAGVNRWIKEIQKVTKLNRDPSTGTALQEISFWLNLEHSLDKIQEKRESLEVALTLAILKQAKRFHATTSFDTDTALSSAKIQVKDYNQLMKDFPINDLLSASQLDKISEALQQIFSHLKKVRATKYPVNRIIKLMEALSRDLTTQLMKVISNMHLMSMPYDEFEKIFTACQQVFSTWEDEYDKMQNLLR-DIAKKKREEFTKFAWKMNATHKKLQTRLENIKKFRYQHEQLRQVIVRVLKPVTKVVPSVEAGVPKDQITDKGDKSSTFLPESADTSSIDEVNAAYEIVKVIDCLDFAKEENDEWDAAIKRYEERIDRVESRIASHLRDLLGQSKNANEMFRYFSRFNALF-VRPHIRGAIGEYQTQLIQRVKDDIEALHNKFKVQYASSTACKMSKVRDLPPVSGSIIWVRQILRQLNAYMKRVEDVLGKDWAQHIEGQKLKADGESFKLKLNTSELFEEWSKKVAEKSLSVAGSIFNVESTRTVVTVRDREPQKITVLKLKVNFLPDVITLAKEVRNMRALGFRTPLSIVNKAHSANQLYPFAISLIESVRTYESTCSKIEEHKMQNISLLTAGLRKDVQ---LCIHEGVQITWESYR-----LDQYVQKLAELVFSFQEKVDDLVIV-------IKEIDFNVKALETCSYNKQTFEEILIRIQEAVDNMSLHQFSNLAQWVSNLDSLVEQRLIVRLEAGLLEWIKVLKGXXXXXXXXXXXXXXXVNSMAKHRLGGKPQIKKLIHELRITNQQMHLYPSIEVATQDILYQMSSWQNIILNLSRIVHSRYQVGLETESDNQKTYKKLLSSLPNSGESLENAYAAVHNILRDANEYVKTWTNYQSLWDLQGDQLFSLIADDNTVWMNVLEEIKSMRKHFDVAETQKEFGP-LVIAFGKVQSKVSMKYDNW----HKEVLTKFGQNMGKMMTTLYNEVQRARNELEQQSIDSGGTNESVNFITYTQNIKRKMNTWEKQAEACRAGQNILCRDRFQFPNDWLDSENIQGEWSAFKEIMRRKQETISSQVASLQMKITEEDKIVESKTTEVLGNWEKDKPIAGDLTPEEAVNIIQILEGKFNRLKEERENVQKAKEALELTEIGVKPISEEKVTNALSELHDLKNVWNELKSIWEKIRDMKETPWLSVQPRKLRQDIENLTAQLKELPNSFKQYASFEHVRTLLKMYMKVNASIVELKSEAIKERHWRMLMRKL-------NVSWSLNELQLGKVWDIDLVKNEEIIREVLAIAQGEKALEEYLRQITEVWKNYVLELTNYQSKSKIIKGWDDLFNKVKEHINNVTSMKASPYFKQFEEEATAWEDRLNKINALFDVWIDVQRRWIYLDGIFAGSADIKVLLPVESQRFQSVSTEFLGLMKKVQKSPLVTDVLNIANVQRQLERLADLLGKIQKSLGEYLERQRSSFPRFYFVGDEDLLEIIGNSXXXXXXXXXXXXMFAGVHSIILSEDEKVILGMMSKEGEELRFISPVSIIEHPRINDWLTAMEKEMRVSLAKYLNVAVKEISGWRTESNIDKDKFMVWLDKYQAQIVVLAAQITWSEAVEASLASG------VSLESTMTVVHSTLNMLADTVLYEQPPVRRRKLEHLIIEYVHQRDVLRALHNDGVSSNKNFDWMSQMRFYFDPKQTDPLHQLSIHVANAKFHYGFEYLGVCDRLVQTPLTDRCYLTMTQALEARLGGSPFGPAGTGKTESVKSLGNQLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLSAVSQQIQGIQEALRELMVSKKDSINVELLGKQVHVNPDMAIFITMNPGYAGRSNLPDNLKKLFRSLAMTQPDRQLIAQVMLYSQGFRTAEVLAGKVVPFFKLCDEQLSPQSHYDFGLRALKSVLVSAGNVKRDRIKQEKEKIVARGEEINETAIAEQLPEQEILIQSVMETMVPKLIADDIPLLYSLLTDVFPGVEYRQAEMKRLREELRKVSENKFLVYSDEPNTAGYLWVEKVLQLYQITTIHHGLMMVGPSGSGKTMACRVLLQALENIDGIEGVAHIIDPKSISKDSLYGYMDPNTREWTDGLFTHILRRIIDSVRGE-SNKRQWIVFDGDVDPEWVENLNSVLDDNKLLTLPNGERLAIPPNVRIMFEVQDLKYATLATVSRCGMVWFSEEVLTTGMILTHFLNELKKVQVMEGEEDFSVNQGDTGADADSKISSSPIIQLQTQVSSILAPFFTEDGLIAKCLDYSTTLEHIMDFTRLRALTSLFSMIKQSIRNMIEYNQSHSDFPLNNEQIENYVAKSLISSVVWSMSGDSKLKVREQLSQYIKNISTVDLPTVGGIKNIIDFEVNIQGTWVAWSNKVPQIEVETHKITATDVVVPTMDTVRHEALLYTWLAEHRPVLLCGPPGSGKTMTLFSALRCLPDMEVVGLNFSSATTPELMLKTFDQYCEYRKTPNGIVLAPQQLNKWLIFFCDEINLPDMDKYGTQRVISFLRQMVEHHGFYRITDMQWVSFERIQFVGACNPPTDPGRKPLSHRFLRHVPVVYVDYPGETSLKQIYSTFNRAMLRMLPSLRGYADTLTNAMVEFFLKTQERFTHDMQPHYIYSPREMTRWVRGIHEALKPLESLSVEGLVRIWAHEALRLFQDRLVEEDERHWTDDNINEVALKHFPNINKEEALKRPILYSNWLSKDYSAVTQEELRDYVKARLKVFYEEELDVPLVLFNQVLDHVLRIDRVFRQPQGHLLLIGVSGAGKTTLSRFVSWINGLSVFQVKVHNKYTAEDFDEDLRNVLRRSGCKGEKITFIMDESNVMDSSFLERMNTLLANGEVPGLFEGDELTTLMTQCKEGAIREGLMIDSQEELYKWFTQQICRNLHVVFTMNPSADGLKDKASTSPALFNRCVLNWFGDWSLEAYFQVGKEFTNRLDLERTDYKVPDTLPCIAEGLLPQNPI--YRDVVVNALVFVHQTMHQ-ANVRVQKRGGRTAAITPRHYLDLIAHYMKLSAEKRADLEEQQLHLNNGLKKIEQTVDQVEVMQRSLTKKRQELENMNEAANAKLKQMVQDQQEAEQKKTTGQALKEELAKQEQFVNEKQKTVKQELDQVEPTVNEAKQAVQNIRKKDIQEIKAMKNPPNAVKMAVESICLLLGEKTTDWQSILKVIIKDTFVTSILNFNTD-DVSDNTRETMKKKYLSNPDYNFEKVNKASNACGPMVKWVLAQISYADILKRVEPLRNELTELSDAAEQNRKKSQETEDLIAQLEKSIAKYTEEYATLISQAQTIKSDLASVESKVGRSVALLGSLSSERTRWDSGSETFKAQMATINGDCLLSSAFMAYGGYFDQHMRTSLFNTWCHHLSEADILFRSDLARVEYLSNPDDRLRWQANSLPADDLCVEN-AIILRRYNRYPLIIDPSGQATTFLLNEYKEKKITKTSFLDDSFRKTLESALRFGTPLLVQDVESYDPILNPVLNREVRRTGGRTLITLGDQDIDLSPTFTIFLSTRDPSVEFAPDICSRVTFVNFTVTRSSLQNQCLNAVLKIERPDIDQKRSDLLKAQGEFQLKLRHLEKDLLQSLNEAQGNLLENDKIIARLETLKREAADVAKKVEETDVVMQEVESVSTEYVPLAQSCSNIYFTLEAMNQIHFLYQYSLQLMLDIFSSVLINNPELTNVKAASDRLKIITKNLFQVTYNRLARGM 11717 + N + K T + IK+ VI + I++Q+ + Y GP + S++ +G+ F IK K S + + +K+ ++ L +IE P++ V II KL +K A D+ + E +FLN LQ+ N+W +++ ++RD G+ L E+ FW N L + E+ +S E + L++L AKRFH T+ + +LS YNQ + PI+++ AS L+ + E + S LKK R + YPV R + LM+ +S+++ ++ +S+ L + Y F ++ + W+D + L+R D+ K+ +E K+ T ++ L+ I R + L + I + + P T P +QI D ++ + + + + A + + + +E ++ + L + E Y +F L + P I+ + E Q L+ +K DI L ++ + + ++PP+S I + + +++ ++ +E + G +W +EG+ + + + N ++F W EK+ + N+ +T + +R+ E +LKVNF + E+R++ + F+ P IV A + LYP AI+L+E ++T+ S + NI L+++VQ L + + + WES + + V LA L S + D I+ KE +K+ + + + EEI+ IQ +N+ +N++ +S ++L+ ++ ++ L + KH L K +E RIT+ PS+ + +L + + L+++V + + T+ L+ L + ++N V N+ N YVK W + LW + + ++ + +L+ + + FD+ ++ F LV+ Q + K D+W K +LT + ++ K L+ ++ R R +E I+ I KR + + Q + + L + + +FP+ ++ + + ++S+ ++ + ++ + + + E + + + + + +W KPI+ LTP EA+ I++ +LK++ +V A + L + + +++T+ + E+ VW +K++WE ++ ETPW V L+ D+ N + ELP + KQ+ ++ + + + M VN +VELK A+K RHW M+ R + N+ L E L V ++L NE ++ +++ AQ E +E+ L +I + WK E+ + S K+++ WD L KE + + SMKAS Y+K FE++ E +L K++ + W++VQ W+ L GI + DI+ LP+E+ +F+S+++E+ + + + +V++I N L+ D L I+ SL +LERQR FPRFYF+G++DLL+IIG+ K ++ K KKMF + SII ED I G+ S EGE L + + + + +WL ++ E+++S+ + ++ D V + KY Q ++L+AQ+ W+E VE L + ++ + + LN +D V ++K+E L++EY+H +V+ L N W +FY D L+ + I + Y FEY+G+ +RL+ TPL + T+T +L + GG FGPAGTGKTE+VK+ G LGR V+VFNCD++FD+Q + R+ VG+ Q+GAWGCFDEFNRL+E++LSAVS IQ IQ L+ V K ++ LL ++ ++P A+FIT+NPGY GRS LP+NLKK FR +M P IA+++L GF ++ LA K+V F +L + S +HY FGLR LK VL + + I+E ++ +++S+ ++P L D + L+ +F K + + L+ + S+E +++K +Q Y + L++VG +G GKT + ++ A+ DG V ++ID K ++K+SLYG M T EW DGLFT ILRR+ D + G N R W+VFD D+DPE+VE +NSVLDDNK+LTLPNGERL IPPN RI+FE +L + T AT++RCG++WFS +V + + H LN K + + D+K+S + +L+ +S + + S L HI+ +R L + ++ ++ + Y Q + L+++ +++ + + S++++++GDS + + Q I D + I+ N + ++ ++ +++P + +E H++ D+V+PT+DT++HE + Y L R ++LCGPPGSGKTM + +ALR +VVG+NFS TT E +L ++ Y T G+ L P+ K L+ FCDEINLP +DKYG+Q V+ FLRQ++E GF++ + +WV+ ERI VGACNPPTDPGR P+S RF RH ++Y+ YP SL QIY + +A+ +++P R Y + A V + + + R++ +Q HY++SPRE+TR VRG++ A+ ++ L+R+WA+EA R+F DRLV E++ + + E K+ PN + +L+S LS D+ V + +L ++++ R K F +EEL+VP+V+ ++DH+LRIDR +Q QGH++LIG S GKT L+RFV+W+NGL + Q K+H DFD L+ + K + I+DESN+++++FLERMNTLLAN ++P LF+G+E L+ + GL++D+++ELY WF +I +NLHVVFT+ + +SPALFNRC++NW GDW + QV + + +E TD+ VP+ + + L+ PI RD VVN L+ + +Q V V R +P +++D + +KL K DL+E Q +N GL+K+ ++V +V + ++L+KK EL + A + L +M+ +Q E+E+K+ + +K+ L QE+ + ++++ V + + +EPT+ EA++ V+NI+K+ + EI++M NPP+ VK+ +E++C +LG + ++W+ I + I KD F+ +I++++T + R+ M++++LS+P++ +E +N+AS ACGP+ +WV AQI+++ +L+ V+PLR E+ + + + + E++ LE SI +Y+ LI + IK+++++V++ + RS++L+ SL+ E+ RW + ++ F + G+C++SS + Y G+ ++ R + L + + + + ++YL D++++W L +D +EN +I++ + P ++DPS T + N Y K + SFL++ F K LE+A+RFG+ +++QD E +DPI++ +++RE G R + +GD ++D+S F +F+ + DPS + + SRV V+F + S++ + + L E ++ +KR DL+K E++LKL++LEK LL+ LN +QGN+LEND+++ L LK+EA ++ KK+ E++ + +++ EY + + I+ LE Q H+ Y S+ L F V I T +AA R+ I L+Q Y + + + Sbjct: 85 DANLANKKYSTLLIIKSRSVIVDAEPIATQISAI-YLPGPVNAGNLASIITHGVSSVFGQLIKSDTKTYSVET---IDKTRRKLDDISKQFQQLHTSIETPDLL----AMVPSII--KLAVSKGATSHDYANYLPSNDLESMRFLNILQSIANKWFLVLKQTLAIDRDIKNGSFLDEVEFWSNFYEVLKSLIEQTQSQEFQVCLSVLTNAKRFHNLTNLLNEGSLSDKFKLADKYNQFLSSIPIDEVRQASNLEDLQELFPVLASSLKKFRYSGYPVQRFVVLMDKISQEVMDAILSNLSD--LFQLEYGSFLGLYEKSAGMIEEWDDIVQDVNLLIREDLRKRAPQEL--LIQKLTFTSASVKATLDEILSTRKRFFSLAETI-KSISPSTYHEEIQRLYHPFEQIHD--------------------ISVNFRL---------------KLEQAESEFSKNMLDLEKKLQNTLASFMDSDHCPTEKLSYLVKFKPLMELCPRIKVKVLENQQILLLEIKKDIRQLETGLELL---PKILHVEALNNIPPISARISYFLNVQSRIDNIVQYLEALFGSNWNDTLEGRSISTSIVQLRKETNPHDVFLHWLGNFPEKATA------NLLTTPILKLIRNNEDD----YELKVNFDFALAAAYSELRSLTYMAFQVPSHIVRIARTYMYLYPRAINLVELIQTFFSLSKSLSYTFYTNI-----FLKRNVQTVWLLLQQILITPWESLQEESSEMSCSVHSLARLEKSIDGILSDYQILKNSEPQFAKEFS-GLKSFDGTADDLHEVEEIISNIQAIFENLFTKGLTNVSDHISTFNNLIISIILEKVRLNLKKM-----------------------HFPKHVL------KLSFNEGRITSS-----PSLAAMKRSLLKDIEAL------LNKVVLINFLHDPDHPLSTTLTFNSLVIKLK---DDIQNCIEQVQNLHCKINSYVKEWQKMEFLWQITEEAFLEVVDNSTQRCFGILKGLLDSQSKFDLIISRNNFSKNLVLHTEDAQRHIRSKMDSWILYVSKHLLTIYERDARK----LHEDMNRDREAVEDMDINFTSLKNITVIIEAVNVNKRHLTERDIQIKLLGSVMRALTKLKVRFPSHFVYIDQLDNDFSSLRQSLSYVEQELQKHRVVIAKSLEEGVENINNLSQSLNESWSVRKPISPTLTPPEALKILEFFNESITKLKKKMHSVAAAAKML-----LIPVVLNDQLTHVVEEVKTYDLVWRSIKNLWEDVQRTFETPWCRVDVLLLQSDLANFLRRADELPRAVKQFEMYKSLFSQVNMLTSVNKILVELKDGALKPRHWNMIFRDIGKRQIQKNLLDKL-EFSLKDVMVLNLTLNEILLTKIIERAQKEFVIEKSLNRIKKFWKEAQYEVIEHSSGLKLVREWDVLEQACKEDLEELVSMKASNYYKIFEQDCLDLESKLTKLSEIQVNWVEVQFYWLDLYGILGENLDIQNFLPLETSKFKSLTSEYKMITTRAFQLDTTIEVIHIPNFDTTLKLTIDSLKMIKSSLSTFLERQRRQFPRFYFLGNDDLLKIIGSGKHHDQVSKFMKKMFGSIESIIFLED--FITGVRSVEGEVLNLNEKIELKDSIQAQEWLNILDTEIKLSVFTQFRDCLGQLK--------DGTDIEVVVSKYIFQAILLSAQVMWTELVEKCLQTNQFSKYWKEVDMKIKGLLDKLNKSSDNV--------KKKIEALLVEYLHFNNVIGQLKNCSTKEEARLLWAKVQKFYQKNDTLDDLNSVFISQSGYLLQYKFEYIGIPERLIYTPLLLIGFATLTDSLHQKYGGCFFGPAGTGKTETVKAFGQNLGRVVVVFNCDDSFDYQVLSRLLVGITQIGAWGCFDEFNRLDEKVLSAVSANIQQIQNGLQ---VGKS---HITLLEEETPLSPHTAVFITLNPGYNGRSELPENLKKSFREFSMKSPQSGTIAEMILQIMGFEDSKSLASKIVHFLELLSSKCSSMNHYHFGLRTLKGVLRNCSPL-----------------------ISEFGEGEKTVVESLKRVILPSLGDTDELVFKDELSKIFDSAG-TPLNSKAIVQCLKDAGQRSGFSMSEE-------FLKKCMQFYYMQKTQQALILVGKAGCGKTATWKTVIDAMAIFDGHANVVYVIDTKVLTKESLYGSMLKATLEWRDGLFTSILRRVNDDITGTFKNSRIWVVFDSDLDPEYVEAMNSVLDDNKILTLPNGERLPIPPNFRILFETDNLDHTTPATITRCGLLWFSTDVCSISSKIDHLLN--KSYEAL-----------------DNKLSMFELDKLKDLISDSF-----DMASLTNIFTCSNDLVHILG---VRTFNKLETAVQLAVHLISSYRQWFQN--LDDKSLKDVITLLIKRSLLYALAGDSTGESQRAFIQTINTYFGHDSQELSDYSTIVI--ANDKLSFSSFCSEIPSVSLEAHEVMRPDIVIPTIDTIKHEKIFYDLLNSKRGIILCGPPGSGKTMIMNNALRNSSLYDVVGINFSKDTTTEHILSALHRHTNYVTTSKGLTLLPKSDIKNLVLFCDEINLPKLDKYGSQNVVLFLRQLMEKQGFWKTPENKWVTIERIHIVGACNPPTDPGRIPMSERFTRHAAILYLGYPSGKSLSQIYEIYYKAIFKLVPEFRSYTEPFARASVHLYNECKARYSTGLQSHYLFSPRELTRLVRGVYTAINTGPRQTLRSLIRLWAYEAWRIFADRLVGVKEKNSFEQLLYETVDKYLPNQDLGNISSTSLLFSGLLSLDFKEVNKTDLVNFIEERFKTFCDEELEVPMVIHESMVDHILRIDRALKQVQGHMMLIGASRTGKTILTRFVAWLNGLKIVQPKIHRHSNLSDFDMILKKAISDCSLKESRTCLIIDESNILETAFLERMNTLLANADIPDLFQGEEYDKLLNNLRNKTRSLGLLLDTEQELYDWFVGEIAKNLHVVFTICDPTNNKSSAMISSPALFNRCIINWMGDWDTKTMSQVANNMVDVIPMEFTDFIVPE----VNKELVFTEPIQTIRDAVVNILIHFDRNFYQKMKVGVNPR-------SPGYFIDGLRALVKLVTAKYQDLQENQRFVNVGLEKLNESVLKVNELNKTLSKKSTELTEKEKEARSTLDKMLMEQNESERKQEATEEIKKILKVQEEDIRKRKEVVMKSIQDIEPTILEAQRGVKNIKKQQLTEIRSMVNPPSGVKIVMEAVCAILGYQFSNWRDIQQFIRKDDFIHNIVHYDTTLHMKPQIRKYMEEEFLSDPNFTYETINRASKACGPLYQWVNAQINFSKVLENVDPLRQEMKRIEFESLKTKANLLAAEEMTQDLEASIEVSKRKYSLLIRDVEAIKTEMSNVQANLDRSISLVKSLTFEKERWLNTTKQFSKTSQELIGNCIISSIYETYFGHLNERERADMLVILKRLLGKFAVKYDVNYRFIDYLVTLDEKMKWLECGLDKNDYFLENMSIVMNSQDAVPFLLDPSSHMITVISNYYGNKTVL-LSFLEEGFVKRLENAIRFGSVVIIQDGEFFDPIISRLISREFNHAGNRVTVEIGDHEVDVSGDFKLFIHSCDPSGDIPIFLRSRVRLVHFVTNKESIETRIFDITLTEENAEMQRKREDLIKLNTEYKLKLKNLEKRLLEELNNSQGNMLENDELMVTLNNLKKEAMNIEKKLSESEEFFPQFDNLVEEYSIIGKHSVKIFSMLEKFGQFHWFYGISIGQFLSCFKRVFIKKSRET--RAARTRVDEILWLLYQEVYCQFSTAL 3690 HSP 2 Score: 108.612 bits (270), Expect = 2.255e-23 Identity = 86/291 (29.55%), Postives = 141/291 (48.45%), Query Frame = 3 Query: 12267 DPSGRVEDLASEQGKQLTGIAIGSAEGFSQAEKAINSAAKTGKWVMLKNVHLATSWLVS-LEKKIHSLQA---HPNFRLFLTMEIT-PKLPVNLLRAGRVLVFEPPPGIKANLLRTLSSI-NNQRMSKEPVERSRLY--FLLAWLNAIVQERLRYVPLGYSKKYEFGESDFKCALDTIDTWVDGAAMGRTNLPPEKIPWVALQTLLGSCIYGGKIDNAFDQRLLNSFLGYLFTEKCFDHNFALVSDADDGSNIAFP--------ESTKHTDILQWVHKLPDLQTPSWLGLP 13091 D + ++ +LA + L I +GS E + A++ I+ + G W++L+N+ ++ SW+ + L K + +A H F++F+T +T KLP LL+ V+E PGI L T+ + +Q + + +Y FLL+W +A++ R R VP G+SKKY F + DF+ A ++ + A TN IPW ++ + + +YGGKID D ++ ++F C N +V G I P E + T IL + D SWL LP Sbjct: 3795 DGTFKLIELAKASKESLKIIPLGSIENLNYAQEEISKSKIEGGWILLQNIQMSLSWVKTYLHKHVEETKAAEEHEKFKMFMTCHLTGDKLPAPLLQRTDRFVYEDIPGI----LDTVKDLWGSQFFTGKISGVWSVYCTFLLSWFHALITARTRLVPHGFSKKYYFNDCDFQFASVYLENVL---ATNSTN----NIPWAQVRDHIATIVYGGKIDEEKDLEVVAKLCAHVF---CGSDNLQIVP----GVRIPQPLLQQSEEEERARLTAILSNTIEPAD-SLSSWLQLP 4066
BLAST of Cytoplasmic dynein 1 heavy chain 1 vs. Ensembl Nematostella
Match: EDO43994 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RXA1]) HSP 1 Score: 6039.14 bits (15666), Expect = 0.000e+0 Identity = 2925/4680 (62.50%), Postives = 3630/4680 (77.56%), Query Frame = 3 Query: 126 QEITAISLPKFIKYLTLYAFPCMLNDDESKSRKDYELFLSEPQNEECLTKFINDNQVTTLTIQQT--KRXXXXXXXXXXXXKISNE-----------VNFESNKSQTSIFIKNNQVIEADKTISSQLQVLSYCDGPPFETMHSLVCYGLLPYFXXXXXXXXXXXXXXXXXMVPSVEKKIAELEIGLLHLQQNIEIPEITLTPHPYVAHIIQEKLLQNKEAR---VSDFEDKFEDTQFLNQLQAGVNRWIKEIQKVTKLNRDPSTGTALQEISFWLNLEHSLDKIQEKRESLEVALTLAILKQAKRFHATTSFDTDTALSSAKIQVKDYNQLMKDFPINDLLSASQLDKISEALQQIFSHLKKVRATKYPVNRIIKLMEALSRDLTTQLMKVISNMHLMSMPYDEFEKIFTACQQVFSTWEDEYDKMQNLLRDIAKKKREEFTKFAWKMNATHKKLQTRLENIKKFRYQHEQLRQVIVRVLKPVT---KVVPSVEAGVPKDQITDKGDKSSTFLPESADTSSIDEVNAAYEIVKVIDCLDFAKEENDEWDAAIKRYEERIDRVESRIASHLRDLLGQSKNANEMFRYFSRFNALFVRPHIRGAIGEYQTQLIQRVKDDIEALHNKFKVQYASSTACKMSKVRDLPPVSGSIIWVRQILRQLNAYMKRVEDVLGKDWAQHIEGQKLKADGESFKLKLNTSELFEEWSKKVAEKSLSVAGSIFNVESTRTVVTVRDREPQKITVLKLKVNFLPDVITLAKEVRNMRALGFRTPLSIVNKAHSANQLYPFAISLIESVRTYESTCSKIEEHKMQNISLLTAGLRKDVQLCIHEGVQITWESYRLDQYVQKLAELVFSFQEKVDDLVIVIKEIDFNVKALETCSYNKQTFEEILIRIQEAVDNMSLHQFSNLAQWVSNLDSLVEQRLIVRLEAGLLEWIKVLKGXXXXXXXXXXXXXXXVNSMAKHRLGGKPQIKKLIHELRITNQQMHLYPSIEVATQDILYQMSSWQNIILNLSRIVHSRYQVGLE-TESDNQKTYKKLLSSLPNSGESLENAYAAVHNILRDANEYVKTWTNYQSLWDLQGDQLFSLIADDNTVWMNVLEEIKSMRKHFDVAETQKEFGPLVIAFGKVQSKVSMKYDNWHKEVLTKFGQNMGKMMTTLYNEVQRARNELEQQSIDSGGTNESVNFITYTQNIKRKMNTWEKQAEACRAGQNILCRDRFQFPNDWLDSENIQGEWSAFKEIMRRKQETISSQVASLQMKITEEDKIVESKTTEVLGNWEKDKPIAGDLTPEEAVNIIQILEGKFNRLKEERENVQKAKEALELTEIGVKPISEEKVTNALSELHDLKNVWNELKSIWEKIRDMKETPWLSVQPRKLRQDIENLTAQLKELPNSFKQYASFEHVRTLLKMYMKVNASIVELKSEAIKERHWRMLMRKLNVSWSLNELQLGKVWDIDLVKNEEIIREVLAIAQGEKALEEYLRQITEVWKNYVLELTNYQSKSKIIKGWDDLFNKVKEHINNVTSMKASPYFKQFEEEATAWEDRLNKINALFDVWIDVQRRWIYLDGIFAGSADIKVLLPVESQRFQSVSTEFLGLMKKVQKSPLVTDVLNIANVQRQLERLADLLGKIQKSLGEYLERQRSSFPRFYFVGDEDLLEIIGNSXXXXXXXXXXXXMFAGVHSIILSEDEKVILGMMSKEGEELRFISPVSIIEHPRINDWLTAMEKEMRVSLAKYLNVAVKEISGWRTESNIDKDKFMVWLDKYQAQIVVLAAQITWSEAVEASLASGVS-------LESTMTVVHSTLNMLADTVLYEQPPVRRRKLEHLIIEYVHQRDVLRALHNDGVSSNKNFDWMSQMRFYFDPKQTDPLHQLSIHVANAKFHYGFEYLGVCDRLVQTPLTDRCYLTMTQALEARLGGSPFGPAGTGKTESVKSLGNQLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLSAVSQQIQGIQEALRELMVSKKDSINVELLGKQVHVNPDMAIFITMNPGYAGRSNLPDNLKKLFRSLAMTQPDRQLIAQVMLYSQGFRTAEVLAGKVVPFFKLCDEQLSPQSHYDFGLRALKSVLVSAGNVKRDRIKQEKEKIVARGEEINETAIAEQLPEQEILIQSVMETMVPKLIADDIPLLYSLLTDVFPGVEYRQAEMKRLREELRKVSENKFLVYSDEPNTAGYLWVEKVLQLYQITTIHHGLMMVGPSGSGKTMACRVLLQALENIDGIEGVAHIIDPKSISKDSLYGYMDPNTREWTDGLFTHILRRIIDSVRGESNKRQWIVFDGDVDPEWVENLNSVLDDNKLLTLPNGERLAIPPNVRIMFEVQDLKYATLATVSRCGMVWFSEEVLTTGMILTHFLNELKKVQVMEGEEDFS-VNQGDTGADADSKISSSPIIQLQTQVSSILAPFFTEDGLIAKCLDYSTTLEHIMDFTRLRALTSLFSMIKQSIRNMIEYNQSHSDFPLNNEQIENYVAKSLISSVVWSMSGDSKLKVREQLSQYIKNISTVDLPTVGGIKNIIDFEVNIQGTWVAWSNKVPQIEVETHKITATDVVVPTMDTVRHEALLYTWLAEHRPVLLCGPPGSGKTMTLFSALRCLPDMEVVGLNFSSATTPELMLKTFDQYCEYRKTPNGIVLAPQQLNKWLIFFCDEINLPDMDKYGTQRVISFLRQMVEHHGFYRITDMQWVSFERIQFVGACNPPTDPGRKPLSHRFLRHVPVVYVDYPGETSLKQIYSTFNRAMLRMLPSLRGYADTLTNAMVEFFLKTQERFTHDMQPHYIYSPREMTRWVRGIHEALKPLESLSVEGLVRIWAHEALRLFQDRLVEEDERHWTDDNINEVALKHFPNINKEEALKRPILYSNWLSKDYSAVTQEELRDYVKARLKVFYEEELDVPLVLFNQVLDHVLRIDRVFRQPQGHLLLIGVSGAGKTTLSRFVSWINGLSVFQVKVHNKYTAEDFDEDLRNVLRRSGCKGEKITFIMDESNVMDSSFLERMNTLLANGEVPGLFEGDELTTLMTQCKEGAIREGLMIDSQEELYKWFTQQICRNLHVVFTMNPSADGLKDKASTSPALFNRCVLNWFGDWSLEAYFQVGKEFTNRLDLERTDYKVPDTLPCIAEGLLPQNPIYRDVVVNALVFVHQTMHQANVRVQKRGGRTAAITPRHYLDLIAHYMKLSAEKRADLEEQQLHLNNGLKKIEQTVDQVEVMQRSLTKKRQELENMNEAANAKLKQMVQDQQEAEQKKTTGQALKEELAKQEQFVNEKQKTVKQELDQVEPTVNEAKQAVQNIRKKDIQEIKAMKNPPNAVKMAVESICLLLGEKTTDWQSILKVIIKDTFVTSILNFNTDDVSDNTRETMKKKYLSNPDYNFEKVNKASNACGPMVKWVLAQISYADILKRVEPLRNELTELSDAAEQNRKKSQETEDLIAQLEKSIAKYTEEYATLISQAQTIKSDLASVESKVGRSVALLGSLSSERTRWDSGSETFKAQMATINGDCLLSSAFMAYGGYFDQHMRTSLFNTWCHHLSEADILFRSDLARVEYLSNPDDRLRWQANSLPADDLCVENAIILRRYNRYPLIIDPSGQATTFLLNEYKEKKITKTSFLDDSFRKTLESALRFGTPLLVQDVESYDPILNPVLNREVRRTGGRTLITLGDQDIDLSPTFTIFLSTRDPSVEFAPDICSRVTFVNFTVTRSSLQNQCLNAVLKIERPDIDQKRSDLLKAQGEFQLKLRHLEKDLLQSLNEAQGNLLENDKIIARLETLKREAADVAKKVEETDVVMQEVESVSTEYVPLAQSCSNIYFTLEAMNQIHFLYQYSLQLMLDIFSSVLINNPELTNVKAASDRLKIITKNLFQVTYNRLARGMLHEDQITFATILARIFLKGSTPIGFLENEFQHFLRSQEATITSSDSNKQDNLGLTLHQDQIDSVKRLKKLKVFAKIEEKVKSTKD-IKNWTLTVTPESNVPELWVDDNNYNDEKLSKIAKGMYNLLIIQAIRPDRLLASTQKFIASVLGDTFTESVRGTLDLASIVEVEVTACVPILLCAVQGYDPSGRVEDLASEQGKQLTGIAIGSAEGFSQAEKAINSAAKTGKWVMLKNVHLATSWLVSLEKKIHSLQAHPNFRLFLTMEITPKLPVNLLRAGRVLVFEPPPGIKANLLRTLSSINNQRMSKEPVERSRLYFLLAWLNAIVQERLRYVPLGYSKKYEFGESDFKCALDTIDTWVDGAAMGRTNLPPEKIPWVALQTLLGSCIYGGKIDNAFDQRLLNSFLGYLFTEKCFDHNFALVSDADD--GSNIAFPESTKHTDILQWVHKLPDLQTPSWLGLPNSAEKVLLTNLGQSLIGNILKMQQSLEDDEELVVGQSKTKRTIEVGDGRPAWMRQLYQSTQTWLQILPKSVTPLQRTIENIKDPMYRCFEREVNSGCNLLASVRKDLEDVAEVCKGAKKPTNHHRSMMADLAKGIIPKMWIRYAIPPGLTVIQWIQDFADRIKQLLHISDTAAKSGVIALRSIQVWLGGLFMAEAYITATRQSVAQNNKWALEELFLDVELGEG-----KVDSNTCVITGLRLMGSEIVDPRTLKLSTLIYKDIDICRLKWIRVEKSQQLEGSSAKDKVCLPIYLNAARSTVLFTLYFSTTDSS---YDFYKRGVAI 14048 +E+ + F+ YL P +L + E + + + L + + + + KF+ D Q+ +L +Q+T K EEE NE V++ + K + FIK V+EADK I+SQ++V++ +G P+ET+H+ + + PYFKS+++K GK MVPSVEKKIAELE+GLLHLQQNI+IPEITL H Y+ ++ K N E R V DF DK ED+ FLNQLQ GVNRWI+EIQKVTKL+RDP++GTALQEISFWLNLE +L +IQ+ RES ++ALTL ILK KRFHAT SFD+DT L A V DYN LMKDFP++DLL+A++LDKI +AL IFSHLKK+R+TKYP+ R ++L+EA+SRDL++QL+KV+ LM + ++EFEKI AC +VFSTW+DEY+K+Q LLRDI KKKREE K W++N HK+LQ RLE ++KFR QHEQLR VIVRVL+P T PS +P + ++ + +T L + AD ++I EVN AYE VK +D LD +KE +D W+AAIKRY+ERIDRVE+RI + LRD LG +KNANEMFR FSRFNALFVRPHIRGAI EYQTQLIQRVKDDIEALH+KFKVQY S ACKMS+VRDLPPVSGSIIW RQI RQL+AYM RVEDVLGK W H+EGQ+LKADG++F+ KLNT ELF++WS+KV ++SL V G IF +ES R R + LKLKVNFLP++ITL+KEVRN++ LGFR PL+IVNKAH ANQLYPFAISLIESVRTYE TC K+EE ++I+ L AGLRK+VQ I EG+ + WESY+LD YVQKLAE VF+FQEKVDDL+ +++ID V++L+TCSYN QTF ++L +IQ+AVD ++LH +SNL WV+ LD VE L RL+AG+ W LKG DD D + SMA H+ GG P+I IHE+ I NQ + + P +E A + ++ ++ +W II L RI SRYQVGLE ES++ +Y+ LL+ LP E L++AY ++ +I+ +Y K W YQ+LWD+ +++ + + WM +L++IK R FD +E++K FGP+VI + +VQSKV+MKYD WHK++L+KF +G M+ Y + +AR+++EQQSI+ T+++V FIT Q++KRK+ W+ E + GQ IL R RF FP WL +N++GEW AF +I++RK +I +QVA+LQMKI ED+ VE++T+++L +WEK KP+AG + P++A+N + I EGKF RLKE+R+NV KAKEALEL E G SEE+V A EL DLK VW+EL +WEK+ ++KE PWLSVQPRKLRQ ++ L + +K LP +QYASFE V+ +K Y+K+N IVELKSEA+KERHW+ LMR+L+V+W L +L LG+VWD+DL KNE ++++ + +AQGE ALEE+L+Q+ +VW ++ L+L NYQ++ +II+GWDDLF KVKEHIN++++MK SPY+K FEE+A WE++LN+I+ FDVWIDVQRRW+YLDGIF+GSADIK LLPVE+QRF S+STEFL LMKKV KSP++ DVLNI VQRQLERLADLLGKIQK+LGEYLER+R+SFPRFYFVGDEDLLEIIGNSK + KLQKHFKKMFAGV +I L+EDE +I G+ SKEGEE+ F PVS+ EHP++N+WLT +E EMR +LA L +VKEI + TE +D +M W+D YQAQ+VVLAAQI+WSE+ E +L + LE + VV +TLN+LAD+VL EQPPVRRRKLEHLIIE+VHQRDV R+L N GV+ NK F+W+SQMRFYFDPKQ + L QLSIH+ANAKF+YGFEYLGV D+LV TPLTDRCYLTMTQALE RLGGSPFGPAGTGKTESVK+LG QLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLSAVSQQIQ IQ AL+E SI +EL+GKQV V+ +MAIFITMNPGYAGRSNLPDNLKKLFRSLAMT+PDRQLIA+VMLYSQGFRTAE LA K+VPFFKLCDEQLS QSHYDFGLRALKSVL+SAGNVKRD+I++ KEK++A+GE+ +E AI+E L EQEILIQSV ETMVPKL+A+DIPLL SLL+DVFPG++Y AEM +L+ E++KV L Y + G WVEKVLQLYQI IHHGLMMVGPSGSGK+ A RVLL+ALE ++G+EG+ H+++PK+ISK+ LYG +DPNTREWTDGLFTH+LR+II++VRGE KRQWIVFDGDVDPEWVENLNSVLDDNKLLTLPNGERLAIPPNVRIMFEVQDL++ATLATVSRCGMVWFSE+VL+T MI L ++KV + E EE+ + G D SP +QLQ V IL +F+ +GL+ KCL+++ EH+MDFTR+RAL SLFSM+ Q +RN+++YNQ H DFP++ + +E Y+ + L+ S++WS +GD KL+VRE L +IK I+T+ LP+ IIDFEVN+QG W+ W +KVPQIEVETHK+ + DVVVPT+DTVRHE LLYTWLAEH+P++LCGPPGSGKTMTLFSALR LPDMEVVGLNFSSATTPEL+LKTFD YCEYR+TPNGIVLAP QL KW++ FCDEINLPD+D YGTQRVISFLRQ+VEH GFYR +D WV+ ERIQFVGACNPPTDPGRKPLSHRFLRHVPV+YVDYPG TSL QIY TFNRAMLRM+PSLR YA LT+AMVEF+ +QERFT DMQPHYIYSPREM+RWVRGI EA++PLES+S+E LVRIWAHEALRLFQDRLVEEDER WTD+N++ VALKHFPN++K++AL RPILYSNWLSKDY AV +EELRD+VKARLKVFYEEELDVPLVLFN+VLDHVLRIDR+FRQPQGHLLLIGVSGAGKTTLSRFV+W+NGLSVFQVK+H KYTA DFDEDLRNVLRR+GCK EKITFI+DESN+M+SSFLERMNTLLANGEVPGLFEGDE TTLMTQCKEG+ REGLM+DS EELYKWFTQQ+ NLHVVFTMNPS++GLKD+A+TSPALFNRCVL+WFGDWS A +QVGKEF+++LDL++++Y P LP + E L PQ P +R+ VVNA VFVHQT+HQAN R+ KRGGR AITPRHYLD I HY+KL +EKR+DLEEQQLHLN GL+KI +TVDQVE +Q+SL+ K QELE N AN KLKQMV+DQQEAE+KK T ++ + KQ + + EKQ+ V ++L QVEP V+EA+QAV+ I+K+ + E++ M NPP VK+A+ESICLLLGE+ DW+ I +IIKD F+ +I+NF+T+D+SD+ TM+ KYLSNPDY FEK N+AS ACGP+VKW +AQ+ YAD+L RVEPLRNEL L A+ ++ K++E +I++LE+SI++Y EEYA LISQAQ IK+DL++VE KV RS ALL SLS ER RW++GS F+ QM TI GD LLSSAF+AYGGYFDQ R +LF+TW HL +A+I FR D+ARVEYLS DDRL+WQANSLPADDLC ENAI+L+R+NRYPLIIDPSGQAT F++NEY+ +KI KTSFLDD+FRK LESALRFG PLLVQDVESYDPILNPVLNRE+RRTGGR LI+LGDQDIDLSP+FTIFLSTRDP++EF PD+CSRVTFVNFTVTRSSLQ+QCLN VLK ERPD+D+KRSDLLK QGEF L+LRHLEK LLQ+LNEA+G +L++D+IIA LE LK+EAA++ +KVEETDV+M EVE+VS +Y L+ CS++YFT+EA+N +HFLYQYSLQ LDIF VL NP L N++ + RLK++T +LFQ+ YNR+ARGM H D++TFA +L RI+L+ LE EF FLR E +T L +Q + RL K+ F +I + S K +W V PE VP W + +KL+ I +Y LL+IQA+RPDR++A K +A +LG F + LDL S+VE EV A P+L+C+V GYD SG VEDLA+++ LT IAIGSAEGFS AEKAINSA K+G+WVMLKNVHLA WLV+LEKK+H+L H +FRLFLTMEI PK+PVNLLRA RV +FEPPPG+KANLLRT S++ RM + P ER+RLYFLLAWL+AIVQERLRY PLG+SK YEF ESD K DT+DTW+D A GRTNLPP K+PW AL+ LL S IYGG+IDN FDQRLL++F+ LFT F+ +FALV+D D G NI+ PE + +QWV LPD QTPSWLGLPN+AEK+LLT GQ LI +LKMQ L DD+EL T++ D RPAWMR L+ + WL ++PKS+T L+RT++NIKDP++R FEREVN+G LL +V +DL D VC+ KKPTN+ R +M+DLAKGI+P W RY +P GLTV+QW+ DF+DRIKQL IS A SG L+++ +WLGG+F+ EAYITATRQ VAQ N W+LEEL L+V + K+D + +TGL+L G+ + L+L+T I D+ + LKWIR+ S S+ V LP+YLN +R+ +LFT+ + T S + FY+RGVA Sbjct: 12 EEVAIVETTIFVSYLR-RVVPLLL-EGEPEVPLELDSALKDAVHLDHVKKFLADAQIRSLLVQRTPLKDEEEGEEAASTESGSDNEKERAIYTLDLDVHYTAPKLASVAFIKRGAVVEADKKIASQIRVINLNEGSPYETLHAYISNAVAPYFKSFVRKSGKADRDGDK-MVPSVEKKIAELEMGLLHLQQNIDIPEITLPIHQYITMMV--KKCSNDEGRRPKVQDFGDKVEDSTFLNQLQNGVNRWIREIQKVTKLDRDPASGTALQEISFWLNLERALLRIQDIRESPDIALTLDILKHGKRFHATVSFDSDTGLKQALATVNDYNPLMKDFPLDDLLAATELDKIRQALVAIFSHLKKIRSTKYPIQRALRLVEAISRDLSSQLLKVLGTRRLMHITHEEFEKIMVACFEVFSTWDDEYEKLQGLLRDIVKKKREESLKMVWRVNPAHKRLQARLEQMRKFRRQHEQLRAVIVRVLQPPTVSQAAPPSPGGAIPA--MPEEEEAKATLLLDPADANAIQEVNLAYENVKEVDGLDVSKEGSDAWEAAIKRYDERIDRVETRITARLRDQLGTAKNANEMFRIFSRFNALFVRPHIRGAIREYQTQLIQRVKDDIEALHDKFKVQYPYSKACKMSRVRDLPPVSGSIIWARQIDRQLSAYMHRVEDVLGKGWENHVEGQRLKADGDNFRQKLNTQELFDDWSRKVQQRSLVVTGRIFAIESQRA------RGGGRGNQLKLKVNFLPEIITLSKEVRNLKWLGFRVPLAIVNKAHQANQLYPFAISLIESVRTYERTCEKVEEK--ESIAPLVAGLRKEVQALISEGIGLVWESYKLDPYVQKLAEAVFNFQEKVDDLLSSVEKIDIEVRSLDTCSYNNQTFRDVLGKIQKAVDELNLHSYSNLPSWVNTLDQQVEMHLSRRLQAGIKSWTDCLKGNKSSRHVDDTD----MASMAAHKPGGDPEIIVSIHEVCIQNQVLFMRPPVEHAREHLINELHAWVGIITTLPRIQSSRYQVGLERDESESDISYRNLLAMLPEGPEVLQDAYGSIEDIVEAVEKYSKVWLQYQALWDMDIGLVYNRLGEGLDKWMKLLKDIKKSRVTFDTSESKKVFGPIVIDYAQVQSKVNMKYDTWHKDILSKFASRLGDNMSDFYGSISKARSDMEQQSIEGASTSDAVGFITVVQSLKRKLKNWDVNVEMYKEGQRILERQRFAFPPSWLYVDNVEGEWGAFNDILKRKDSSIQTQVATLQMKIITEDQSVETRTSDLLTDWEKGKPVAGSMRPDQALNNLAIYEGKFTRLKEDRDNVAKAKEALELMEPGTLAPSEERVLVAFEELQDLKGVWSELAKVWEKVDELKERPWLSVQPRKLRQSLDELLSDMKNLPARLRQYASFEFVQKTIKTYLKMNMLIVELKSEALKERHWKTLMRRLHVNWVLTDLTLGQVWDVDLQKNEAVVKDTILVAQGEMALEEFLKQVRDVWHSFELDLVNYQNRCRIIRGWDDLFTKVKEHINSISAMKLSPYYKVFEEDALQWEEKLNRIHDTFDVWIDVQRRWVYLDGIFSGSADIKTLLPVETQRFSSISTEFLSLMKKVAKSPMMMDVLNIQGVQRQLERLADLLGKIQKALGEYLERERASFPRFYFVGDEDLLEIIGNSKSIPKLQKHFKKMFAGVATITLNEDETLITGLSSKEGEEVEFQKPVSLKEHPKVNEWLTCVENEMRTTLATLLAASVKEIHQFNTE-QVDNSVYMKWVDTYQAQLVVLAAQISWSESCENALQQIANNPKDMSPLEKVLKVVEATLNVLADSVLQEQPPVRRRKLEHLIIEHVHQRDVTRSLLNCGVTGNKAFEWLSQMRFYFDPKQKEVLQQLSIHMANAKFNYGFEYLGVQDKLVTTPLTDRCYLTMTQALEGRLGGSPFGPAGTGKTESVKALGQQLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLSAVSQQIQTIQLALKESADDTTSSITIELVGKQVRVSRNMAIFITMNPGYAGRSNLPDNLKKLFRSLAMTKPDRQLIAEVMLYSQGFRTAEKLASKIVPFFKLCDEQLSNQSHYDFGLRALKSVLISAGNVKRDKIQKIKEKLIAKGEKADEAAISEGLNEQEILIQSVYETMVPKLVAEDIPLLQSLLSDVFPGIKYVSAEMDQLKAEIKKVCAEMHLTYGEGEEQGGS-WVEKVLQLYQICQIHHGLMMVGPSGSGKSSAWRVLLKALERVEGVEGICHVLNPKAISKEFLYGTLDPNTREWTDGLFTHVLRKIIENVRGELGKRQWIVFDGDVDPEWVENLNSVLDDNKLLTLPNGERLAIPPNVRIMFEVQDLRFATLATVSRCGMVWFSEDVLSTEMIFDSNLTRMRKVPLEEAEEESRRIQSAPQGEDV-----LSPSMQLQRDVVEILQEYFSSNGLVMKCLEFAFKQEHVMDFTRMRALESLFSMVHQGVRNVLQYNQQHPDFPMDRDGLELYIPRFLVFSLLWSFAGDGKLRVREDLGNFIKGITTIPLPSSSSTP-IIDFEVNLQGEWILWQSKVPQIEVETHKVASPDVVVPTLDTVRHETLLYTWLAEHKPLVLCGPPGSGKTMTLFSALRALPDMEVVGLNFSSATTPELLLKTFDHYCEYRRTPNGIVLAPAQLGKWMVLFCDEINLPDVDHYGTQRVISFLRQIVEHGGFYRSSDQAWVTLERIQFVGACNPPTDPGRKPLSHRFLRHVPVIYVDYPGATSLSQIYGTFNRAMLRMMPSLRTYAQPLTDAMVEFYTMSQERFTQDMQPHYIYSPREMSRWVRGICEAMRPLESMSIEQLVRIWAHEALRLFQDRLVEEDERRWTDENVDFVALKHFPNVDKQQALGRPILYSNWLSKDYVAVDREELRDFVKARLKVFYEEELDVPLVLFNEVLDHVLRIDRIFRQPQGHLLLIGVSGAGKTTLSRFVAWMNGLSVFQVKIHRKYTAADFDEDLRNVLRRTGCKNEKITFILDESNIMESSFLERMNTLLANGEVPGLFEGDEYTTLMTQCKEGSQREGLMLDSSEELYKWFTQQVMTNLHVVFTMNPSSEGLKDRAATSPALFNRCVLDWFGDWSTGALYQVGKEFSSKLDLDKSNYSAPPYLPVVYEEL-PQPPTHREAVVNAYVFVHQTLHQANARLAKRGGRVMAITPRHYLDFINHYVKLFSEKRSDLEEQQLHLNVGLQKIRETVDQVEELQKSLSLKSQELEAKNALANQKLKQMVKDQQEAEKKKVTSMEIQTTIEKQTKQIKEKQQAVMKDLAQVEPAVDEARQAVKGIKKQHLVELRTMGNPPATVKLALESICLLLGEQAADWKQIRAIIIKDNFIPTIVNFSTEDISDSVTRTMQSKYLSNPDYTFEKANRASQACGPLVKWAIAQLQYADMLNRVEPLRNELKSLEMEAQASKIKAEEISRVISELERSISQYKEEYAALISQAQAIKTDLSAVEDKVSRSTALLRSLSVERQRWEAGSNAFQTQMGTIVGDVLLSSAFLAYGGYFDQQYRQNLFSTWAQHLQQANIQFRPDIARVEYLSTADDRLKWQANSLPADDLCTENAIMLQRFNRYPLIIDPSGQATEFIMNEYRGRKINKTSFLDDAFRKNLESALRFGNPLLVQDVESYDPILNPVLNRELRRTGGRVLISLGDQDIDLSPSFTIFLSTRDPTIEFPPDLCSRVTFVNFTVTRSSLQSQCLNQVLKAERPDVDEKRSDLLKLQGEFHLRLRHLEKSLLQALNEAKGKILDDDRIIATLEKLKKEAAEITRKVEETDVIMAEVETVSEQYRALSHYCSSLYFTMEALNMVHFLYQYSLQFFLDIFQCVLYENPHLQNIRDPAPRLKVLTSDLFQIVYNRVARGMKHNDRMTFAILLCRIYLRNLPGEDELEEEFNVFLRGSEMVLTGKIPQIDG-----LSPEQASGITRLSKMAAFKEIHIYINSNKQAFLDWQDAVKPEDEVPTCWSE-----TKKLTPIGIAVYQLLVIQALRPDRIIAMLHKVVAVILGGDFMHAAEQGLDLHSVVEKEVKASTPVLMCSVTGYDASGWVEDLAAQENTPLTSIAIGSAEGFSDAEKAINSAVKSGRWVMLKNVHLAPQWLVTLEKKLHTLSPHASFRLFLTMEINPKVPVNLLRASRVFMFEPPPGVKANLLRTFSAVPAARMCQAPSERARLYFLLAWLHAIVQERLRYAPLGWSKHYEFTESDLKVGCDTLDTWLDSVAQGRTNLPPNKVPWDALRALLSSAIYGGRIDNDFDQRLLSTFVNRLFTVSSFESDFALVTDVDGKKGKNISMPEGIRREQFVQWVEHLPDAQTPSWLGLPNNAEKLLLTQRGQDLIAKLLKMQL-LGDDDELAYSPDATRQKRRESDPRPAWMRTLHTTAANWLTMIPKSLTGLKRTLDNIKDPLFRYFEREVNTGIQLLNTVHQDLSDTVLVCEAQKKPTNYLRGLMSDLAKGILPSNWRRYTVPKGLTVLQWVVDFSDRIKQLQAISQAANASGSSGLKNLSIWLGGMFVPEAYITATRQFVAQANNWSLEELALEVTVANSASDKLKMDDCSFGVTGLKLQGASCYN-NQLELTTTISTDLPLTSLKWIRLLSSSDKPQSTM---VTLPVYLNQSRTELLFTVDMAVTGESARGHRFYERGVAF 4648
BLAST of Cytoplasmic dynein 1 heavy chain 1 vs. Ensembl Nematostella
Match: EDO35852 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SK91]) HSP 1 Score: 1370.14 bits (3545), Expect = 0.000e+0 Identity = 1018/3650 (27.89%), Postives = 1792/3650 (49.10%), Query Frame = 3 Query: 3174 LSSLPNSGESLENAYAAVHNILRDANEYVKTWTNYQSLWDLQGDQLFSLIADDNTV----------WMNVLEEIKSMRKHFDVAETQKEFGPLVIAFGKVQSKVSMKYDNWHKEVLTKFGQNMGKMMTTLYNEVQRARNELEQQSIDSGGTNESVNFITYTQNIKRKMNTWEKQAEACRAGQNILCRDRFQFPNDWLDSENIQGEWSAFKEIMRRKQETISSQVASLQMKITE--EDKIVE-----SKTTEVLGNWEKDKPIAGDLTPEEAVNIIQILEGKFNRLKEERENVQKAKEALELTEIGVKPISEEKVTNALSELHDLKNVWNELKSIWEKIRDMKE----TPWLSVQPRKLRQDIENLTAQLKELPNSFKQYASFEHVRTLLKMYMKVNASIVELKSEAIKERHWRMLMRKLNVSWSLNE--LQLGKVWDIDLVKNEEIIREVLAIAQGEKALEEYLRQITEVWKNYVLELTNY----QSKSKIIKGWDDLFNKVKEHINNVTSMKASPYFKQFEEEATAWEDRLNKINALFDVWIDVQRRWIYLDGIFAGSADIKVLLPVESQRFQSVSTEFLGLMKKVQKSPLVTDVLNIANVQRQLERLADLLGKIQKSLGEYLERQRSSFPRFYFVGDEDLLEIIGNSXXXXXXXXXXXXMFAGVHSIILSED---EKVILGMMSKEGEELRFISPVSIIEHPRINDWLTAMEKEMRVSLAKYLNVAVKEISGWRTESNIDKDKFMVWLDKYQAQIVVLAAQITWSEAVEASL-----ASGVSLESTMTVVHSTLNMLADTVLYEQPPVRRRKLEHLIIEYVHQRDVLRALHNDGVSSNKNFDWMSQMRFYFDPKQTDPLHQLSIHVANAKFHYGFEYLGVCDRLVQTPLTDRCYLTMTQALEARLGGSPFGPAGTGKTESVKSLGNQLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLSAVSQQIQGIQEALRELMVSKKDSINVELLGKQVHVNPDMAIFITMNPGYAGRSNLPDNLKKLFRSLAMTQPDRQLIAQVMLYSQGFRTAEVLAGKVVPFFKLCDEQLSPQSHYDFGLRALKSVLVSAGNVKRDRIKQEKEKIVARGEEINETAIAEQLPEQEILIQSVMETMVPKLIADDIPLLYSLLTDVFPGVEYRQAEMKRLREELR-KVSENKFLVYSDEPNTAGYLWVEKVLQLYQITTIHHGLMMVGPSGSGKTMACRVLLQALENIDGIEGVAHIIDPKSISKDSLYGYMDPNTREWTDGLFTHILRRIIDSVRGESNKRQWIVFDGDVDPEWVENLNSVLDDNKLLTLPNGERLAIPPNVRIMFEVQDLKYATLATVSRCGMVWFSEEVLTTGMILTHFLNELKKVQVMEGEEDFSVNQGDTGADADSKISSSPIIQLQTQVSSILAPFFTEDGLIAKCLDYSTTL--EHIMDFTRLRALTSLFSMIKQSIRNMIEYNQSHSDFPLNNEQIENYVAKSL-----ISSVVWSMSGDSKLKVREQLSQYIKNISTVDL-PTVGGI----------KNIIDFEVNIQG-TWVAWSNKVPQIEVETHKITATDVVVPTMDTVRHEALLYTWLAEHRPVLLCGPPGSGKTMTLFSALRCLPDME---VVGLNFSSATTPELMLKTFDQYCEYRKTPNGIVLAPQQLNKWLIFFCDEINLPDMDKYGTQRVISFLRQMVEHHGFY-RITDMQWVSFERIQFVGACNPPTDPGRKPLSHRFLRHVPVVYVDYPGETSLKQIYSTFNRAMLRMLP-SLRGYADTLTNAMVEFFLKTQERFTHDMQP-----HYIYSPREMTRWVRGIHEALKPLESLSVEGLVRIWAHEALRLFQDRLVEEDERHWTDDNINEVALKHFPNINKEEALKRPIL---YSNWLSKDYSAVTQEELRDYVKARLKVFYEEELD--------VPLVLFNQVLDHVLRIDRVFRQPQGHLLLIGVSGAGKTTLSRFVSWINGLSVFQVKVHNKYTAEDFDEDLRNVLRRSGCKGEKITFIMDESNVMDSSFLERMNTLLANGEVPGLFEGDELTTLMTQCKEGAIREGLMIDSQEELYKWFTQQICRNLHVVFTMNPSADGLKDKASTSPALFNRCVLNWFGDWSLEAYFQVGKEFTNRLDLERTDYKVPDTLPCIAEGLLPQNPIYRDVVVNALVFVHQTMHQANVRVQKRGGRTAAITPRHYLDLIAHYMKLSAEKRADLEEQQLHLNNGLKKIEQTVDQVEVMQRSLTKKRQELENMNEAANAKLKQMVQDQQEAEQKKTTGQALKEELAKQEQFVNEKQKTVKQELDQVEPTVNEAKQAVQNIRKKDIQEIKAMKNPPNAVKMAVESICLLLGEKTTDWQSILKVIIKDTFVTSILNFNTDDVSDNTRETMK-KKYLSNPDYNFEKVNKASNACGPMVKWVLAQISYADILKRVEPLRNELTELSDAAEQNRKKSQETEDLIAQLEKSIAKYTEEYATLISQAQTIKSDLASVESKVGRSVALLGSLSSERTRWDSGSETFKAQMATINGDCLLSSAFMAYGGYFDQHMRTSLFNT-WCHHLSEADILFRSDLARVEYLSNPDDRLRWQANSLPADDLCVENAIILRRYNRYPLIIDPSGQATTFLLNEYKEKKITKTSFLDDSFRKTLESALRFGTPLLVQDVESY-DPILNPVLNREVRRTGGRTLITLGDQDIDLSPTFTIFLSTRDPSVEFAPDICSRVTFVNFTVTRSSLQNQCLNAVLKIERPDIDQKRSDLLKAQGEFQLKLRHLEKDLLQSLNEAQGNLLENDKIIARLETLKREAADVAKKVEETDVVMQEVESVSTEYVPLAQSCSNIYFTLEAMNQIHFLYQYSLQLMLDIFSSVLINNPELTNVKAASDRLKIITKNLFQVTYNRLARGMLHEDQITFATILARIFLKGSTPIGFLENEFQHFLRSQEATITSSDSNKQDNLGLTLHQDQIDSVKRLK-KLKVFAKIEEKV-KSTKDIKNWTLTVTPESN-VPELWVDDNNYNDEKLSKIAKGMYNLLIIQAIRPDRLLASTQKFIASVLGDTFTESVRGTLDLASIVEVEVTACVPILLCAVQGYDPSGRVEDLASEQ---GKQLTGIAIGSAEGFSQAEKAINSAAKTGKWVMLKNVHLATSWLVSLEKKIHSL-QAHPNFRLFLTMEITPKLPVNLLRAGRVLVFEPPPGIKANLLRTLSSINNQRMSKEPVER-SRLYFLLAWLNAIVQERLRYVPLGYSKKYEFGESDFKCALDTIDTWVDGAAMGRTNLPPEKIPWVALQTLLGSCIYGGKIDNAFDQRLLNSFLGYLFTEKCFD--HNFALVSDAD-------DGSNIAFPESTKHTDILQWVHKLPDLQTPSWLGLPNSAEKVLLTNLGQSLIGNILKMQQSLEDDEELVVGQSKTKRTIEVGDGRPAWMRQLYQSTQTWLQILPKSVTPLQRTIENIKDPMYRCFEREVNSGCNLLASVRKDLEDVAEVCKGAKKPTNHHRSMMADLAKGIIPKMWIRYAIPPGLTVIQWIQDFADRIKQLLHISDTAAKSGVIALRSIQVWLGGLFMAEAYITATRQSVAQNNKWALEELFLDVELGE-GKVDSNT------CVITGLRLMGS 13814 +S+ P E + +V N L N+Y+ W Y+ LW L + A N + N++ E+ + DV + PL + + W KE+ ++ + TL E++ +L++ + T E + F+ R M + + + + ++ ++E + G + ++ + + + S++MK TE +D++ SK E N E I DL + V +++ + ++N ++ER+ + A+ L+ I + P ++ EL L+ V+ I+EK ++ ++ T W ++ L I+ QLK LP K + +K + +LK+EA++ERHW+ LM + + LN L ++ ++L ++I ++ A A E +E+ + ++++ W + Y Q + ++ D++ + ++ N+ SM AS + F E WE L+ I + +VW+ VQR+W+YL+ IF G DI+ LP E+++F + F +M K+P V + + N QL+ + + L K QKSL +YL+ +R++FPRF+F+ D++LL I+G S D +Q+H KMF + S+ E E + M+S EGE + F V R+ DW+T++ KEMR + N + + + + + I + + W+ +YQ + + Q+ W+ VE + +++ H ++ L V R+K ++I VH RD++ + D + ++ F+W SQ+RFY+D +L I +F YG+EY+G+ RLV TPLTDR YLT+TQAL LGG+P GPAGTGKTE+ K L LG +V NC E DF+++G+IF GL Q GAWGCFDEFNR++ +LS VS QI+ +Q +L + ++ G ++ ++ M IFITMNPGYAGR+ LP+++K LFR + PD Q I ++ML+S+GF A+VLA K+ +KL QLS QSHYDFGLRALK+VLV AG +KR + +L E +L++++ + +PK + +D+PL L+ D+FPG++ + + + +++NK+++ P+ A +KV+Q+Y+ H M+VGP+G GKT+ L A + G+ ++++ K+ + LYG +DP TR+WTDGL ++I R I + N+R++IVFDGDVD WVEN+NSV+DDNKLLTL NGER+ + + ++FEV DL+YA+ ATVSRCGMV+ + L + N + E EE D L K + S L E I+D + + L ++ + NM+E D L + N++ + ISS++WS R Q IK ++ + P G + + ++ + + WV W + VP+ V + +++VPT+DTVR LL + HRPVLL G G+ KT T + LR + D + ++ +NFSS TT + + E R P + K L+ F D++N+P +D+YGTQ+ I+ L+ ++E G Y R ++ W + I FV A P GR + RF+ V V +P E SL++IYS+ L+ P +++ + +T + +E + D+ P HYI++ R+++R +G+ P S VR+W +E +R+F DRL E +R I+ + ++F + + A++ P L Y N L++D E++ DY K +EE L+ + LVLF+ L+H+ RI RV R QGH LL+GV G+GK +L++ ++ G VF++ + Y F EDL+ + G + +K+ F+ +++V FLE +N +L +G VP L+ DE ++ Q ++ A + G+ ++E ++++F + NLH+V M+P D L+ + P L + K+PD YR+ VV+ +VFVHQT+ + ++ R TP++YLD I+ Y +L K + EQ L GL K+ +Q+ + L ++ + +EA L ++ + Q+A +KK K+E+A+Q + + ++ ++ L P + EAK A+Q++ K D+ EI++ PP AV+M E I L G K W+S ++ + F+ S+ + D ++ T + K + L + E++ + S A + K+V+A + Y + + ++P R ++ L ++++ ++ E + LE+ + + ++Y + + +++ + +E ++ + L+ L SE+ RW + K Q + GDCLL +AF++Y G F R + W + + + +I L+N + +W + LP DDL +EN I+ + +RYPL IDP QA ++ + ++ + +F D F K LE A+++G P+L +DV+ Y DP+++ VL++ ++ GR + LGD+++D P+F ++L+T+ + ++ P SR VN+TVT L++Q L+ ++ +ER +++++R L++ E + L+ LE LL+ L +QGN+L+N +++ LE K +A +V++K++ +++ + Y P A+ + ++F L M+ ++ +YQYSL L++F L + T + S RLK I L YN G+ ++ F+ + ++ + + E FL+ I S++Q Q D ++ + +VF + + + ++ K + W+ PES+ P + +E LS + LL+++ R DR+ + F+ +G+ + L SI+E + T P++ G DP+ + LA G +L +A+G + A + + +A G+W+ML+N HL WL +LEK + + + HP+FRL+LT + TP+ P+ +L+ +V EPP G+K NL T I+NQ ++ P + S L F+L + +A+VQER +Y +G++ Y+F ESDF+ + ++T++ ++ T++ KIPW +L+ L+G +YGG++ + FD+R++ +++ + FD F ++ + +G N P + D ++ +LP TP GL +AE TN + + +++++Q D + + + G+ + + + + +I P +V LQ E++ L+ + L ++ G ++ + L G+IP +W + A ++ W++ F R+ Q + G A+ +WL GL + ++Y+TA Q+ + + W L+ L + + D T C ++GL L G+ Sbjct: 818 ISASPAIIELVTTVSKSVQNTLGTLNKYLNRWKRYRLLWKLDKSNMVMKFAAKNPTCIAYDEKLQFYSNLVLEVGTQPMSRDVEFVRLNLDPLA-------TTIQANARAWVKELGKMLNESAKDNLMTLKGEIETLCTDLKR----APDTLEDLKFVLRVIADIRDM-SLDVELRTADIKERYRTLKMYEIEVSDNETELVNGIDQLWDDLFVESRR-VDYSLVSVKMKFTEITQDQVSNFTSDISKFKESFIN-EGPSSIGTDL--DAGVELLKKFQEEYNTFEKERQELTNAERLFGLS-ITMYP----ELQQMEKELKGLEQVF----GIYEKQKEARDEWANTLWANLDVSVLSDGIDGYIKQLKRLPREVKALPLCHVLEEKMKEFKNSIPLFSDLKNEALRERHWKKLMDMTGMKFDLNPETFTLQNMFAMELHNFSDVIADITASATKELGIEKGIAEVSDTWNAMKFTVAKYMKGTQERGFVLGTVDEILQILDDNAMNLQSMSASRFVGPFLETVNKWEKSLSHIGEVVEVWMVVQRKWMYLESIFIG-GDIRAQLPEEARKFDDIDKTFKKIMADTAKNPKVLEACHAPNRLDQLQFIVNGLEKCQKSLNDYLDSKRNAFPRFFFISDDELLSILG-SHDPTCVQEHMIKMFDNIASLRFQEGSNKETLATAMISSEGESMDFRQAVP--AEGRVEDWMTSVLKEMRRT-----NRLITKEAIYNYCNQITR---IEWMMQYQGMVALAGNQVWWTWEVEDVFRKVKKGDKMGMKNYARKCHRQIDDLVVKVRSNLSKNDRKKFNTVLIIEVHARDIIDSFVRDSIMDSREFEWESQLRFYWDQAP----DELMIRQCTGEFGYGYEYMGLNGRLVITPLTDRIYLTITQALSMYLGGAPAGPAGTGKTETTKDLAKALGLLCVVTNCGEGMDFKSIGKIFSGLAQCGAWGCFDEFNRIDVSVLSVVSTQIKTLQNSLSSGLK------RLQFEGTEIALDARMGIFITMNPGYAGRTELPESVKALFRPVVCIVPDLQQICEIMLFSEGFLYAKVLAKKMTVLYKLASGQLSKQSHYDFGLRALKAVLVMAGELKRG---------------------SPELSEDVVLMRALRDMNLPKFVFEDVPLFLGLIADLFPGLDCPRVRYPNFNDAVESSLTDNKYILL---PHQA-----DKVVQMYETMLTRHTTMIVGPTGGGKTVVINTLAMAQTRL-GMHTKLYVMNAKACTVIELYGTLDPVTRDWTDGLLSNIFREINKPT--DKNERKYIVFDGDVDALWVENMNSVMDDNKLLTLANGERIRLQKHCALLFEVADLRYASPATVSRCGMVYVDPKNLGYRPYWQKWCN--ARSNAKEREE--------------------------------------LDRLFEKYVPASVDLILEGILDGKQGKKLKTIIPLTNL---NMVEQLSHMLDALLPPAESSNFLGPDVTEAIFISSLIWSTGAGLLEDGRIVYDQLIKRLAGIPANPAEGTVVGPGELPSAQPTLYEYYFDSKKLLWVPWLDVVPEY-VHNPDLKYNEILVPTVDTVRTTWLLQLMVNIHRPVLLVGETGTSKTATTANYLRGM-DQDTTLLLNINFSSRTTSINVQHNLEANVEKRTKD---TYGP-PMGKRLLVFMDDMNMPQVDEYGTQQPIALLKLLLEKGGMYDRGKELIWKNVRDIGFVAAMGKPGG-GRNEVDPRFISLFSVFNVTFPSEESLRRIYSSILTGHLQPFPKNIQDLVEHITTSTLELYTN----IIRDLPPTPSKFHYIFNLRDLSRVYQGLC-LTTPDRFDSPAKFVRVWRNECMRVFCDRLTNEADRETVSGYISSLVDQNFSE-HTDIAMRDPCLFGDYRNTLTED--PRLYEDVVDYDAT--KAIFEEILEEYNMDHAPMNLVLFDDALEHLTRIHRVIRMDQGHALLVGVGGSGKQSLTKLAAFSAGCGVFEITLTRGYDENSFREDLKELYNSLGLENKKMVFLFTDAHVAQEGFLELINNMLTSGMVPALYPDDEKEGIIGQVRDEANKAGVP-PARESIWQYFVNKCANNLHIVLAMSPVGDILRTRCRNFPGLND---------------------------------KIPDQ--------------YRETVVDHVVFVHQTVGTYSQSFLQKLRRVNYTTPKNYLDFISTYNRLLEIKDKYVLEQCHRLEGGLGKLLAASEQLAELNEKLAVQKIAVTEKSEACEKLLVEIQRATQQANEKKEMAIGKKKEIAEQNKVIVVEKTEAEEALAAALPALEEAKLALQDLDKSDVTEIRSFAKPPRAVQMVSECIVALRGYKEISWKSAKAMMSEGNFLKSLTEMDVDGIT--TGQVKKCRDMLKEMNTTVEEMKEVSKAGAGLFKFVIAVMGYCSVAREIKPKREKVARLERNFHLSKRELEKIEKELKALEEELERLGKQYDDAMREKSSLQEEAEIMERRLIAADKLISGLGSEKIRWTKDLQDLKDQRVRLLGDCLLGAAFLSYLGAFTWDFRRDMLRKQWENDVIQREIPLSKPFKVDVLLTNDVEVSKWTSEGLPPDDLSIENGILTTQASRYPLCIDPQQQALNWIKKKEEKNNLKVVTFNDHDFLKQLELAIKYGFPILFKDVDEYIDPVIDNVLDKNIKGEPGREFVVLGDKEVDYDPSFRLYLNTKLSNPKYTPAHFSRCMVVNYTVTMKGLEDQLLSVIVGVERKELEEQRERLIQETSENKRLLKDLEDTLLRELATSQGNMLDNVELVQTLEDTKTKAVEVSEKLKLGAKTAIDIDKLRDGYRPAAKLGAVLFFVLSEMSVVNSMYQYSLNSYLEVFDLSLRKSLPDTIL---SKRLKNIMDTLTMNVYNYACTGLFERHKLLFSFQMTIKIMEADGKLK--QEELDFFLK---GNIALEKSSRQKPYSWMPDQGWEDVIRLCQVTPEVFGSLADDIERNEKGWREWSDLDAPESHPFPGKY-------EESLSDFQR----LLLLRCFRVDRVYLAITHFVTGRMGEKYVTP--PVLSFESILE-QSTPFSPVIFILSPGSDPASDLMKLAERSGFGGNKLKFLAMGQGQE-KLALQLLETAISRGQWLMLQNCHLLVKWLRTLEKVLERISKPHPDFRLWLTTDPTPEFPIGILQRSLKVVTEPPNGLKLNLRSTYHKISNQMLADCPHQSFSPLVFVLGFFHAVVQERRKYGKIGWNIAYDFNESDFRVCMTLLNTYLT-KSLQNTDV---KIPWASLKYLIGEVMYGGRVIDDFDRRVVKTYMDEYMGDFIFDTFQPFHFYNNEEVDYCIPKNGENKYDPGRDVYVD---YIEELPLANTPDVFGLHPNAEIGYYTNAAKDMWLHLVELQPQTAGDSGGISREEFITKIASDIQGKLPPLFDVDRVRKNLSEITPTAVVLLQ----------------ELDRFNVLIRRMSTSLINLQRALAGEVGMSSELDEVSRSLFNGMIPNIWRKLAPATLKSLGNWMEHFQKRLDQY----NKWVNDGEPAV----IWLSGLHIPDSYLTALVQATCRKHGWPLDRSTLYTTVTKYHNADEVTERAHSGCFVSGLYLEGA 4224
BLAST of Cytoplasmic dynein 1 heavy chain 1 vs. Ensembl Nematostella
Match: EDO31800 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SWW2]) HSP 1 Score: 1358.2 bits (3514), Expect = 0.000e+0 Identity = 1023/3694 (27.69%), Postives = 1758/3694 (47.59%), Query Frame = 3 Query: 2991 ELRITNQQMHLYPSIEVATQDILYQMSSWQNIILNLSRIVHSRYQVGLETESDNQKTYKKLLSSLPNSGESLEN----------AYAAVHNILRDANEYVKTWTNYQSLWDLQGDQLFSLIA-----DDNTVWMNVLEEIKSMRKHFDVAETQKEFGPLVIAFGKVQSKV---SMKYDNWHKEVLTKFGQNMGKMMTTLYNEVQRARNELEQQSIDSGGTNESVNFITYTQNIKRKMNTWEKQAEACRAGQNILCRDRFQFPN---DWLDSENIQGEWSAFKEIMRRKQETISSQVASLQMKITEEDKIVESKTTEVLGNWEKDKPIAGDLTPEEAVNIIQILEGKFNRLKEERENVQKAKEALELTEIGVKPISEEKVTNALSELHDLKNVWNELKSIWEKIRDMKETPWLSVQPRKLRQDIENLTAQLKELPNSFKQYASFEHVRTLLKMYMKVNASIVELKSEAIKERHWRMLMRKLNVSWSLNE-LQLGKVWDIDLVKNEEIIREVLAIAQGEKALEEYLRQITEVWKNY-VLELTNYQSKSK-IIKGWDDLFNKVKEHINNVTSMKASPYFKQFEEEATAWEDRLNKINALFDVWIDVQRRWIYLDGIFAGSADIKVLLPVESQRFQSVSTEFLGLMKKVQKSPLVTDVLNIANVQRQLERLAD---LLGKIQKSLGEYLERQRSSFPRFYFVGDEDLLEIIGNSXXXXXXXXXXXXMFAGVHSIILS---------EDEKV---------------ILGMMSKEGEELRF--ISPVSIIEHPRIN-DWLTAMEKEMRVSLAKYLNVAVKEISGWRTESNIDKDKFMVWLDKYQAQIVVLAAQITWSEAVEASLASGVSLESTMTVVHSTLNMLADTVLYEQPPVRRRKLEHLIIEYVHQRDVLRALHNDGVSSNKNFDWMSQMRFYFDPKQTDPLHQLSIHVANAKFHYGFEYLGVCDRLVQTPLTDRCYLTMTQALEARLGGSPFGPAGTGKTESVKSLGNQLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLSAVSQQIQGIQEALRELMVSKKDSINVELLGKQVHVNPDMAIFITMNPGYAGRSNLPDNLKKLFRSLAMTQPDRQLIAQVMLYSQGFRTAEVLAGKVVPFFKLCDEQLSPQSHYDFGLRALKSVLVSAGNVKRDRIKQEKEKIVARGEEINETAIAEQLPEQEILIQSVMETMVPKLIADDIPLLYSLLTDVFPGVEYRQAEMKRLREELRKVSENKFLVYSDEPNTAGYLWVEKVLQLYQITTIHHGLMMVGPSGSGKTMACRVLLQALENIDG--------IEGVAHIIDPKSISKDSLYGYMDPNTREWTDGLFTHILRRIIDSVRGESNKRQWIVFDGDVDPEWVENLNSVLDDNKLLTLPNGERLAIPPNVRIMFEVQDLKYATLATVSRCGMVWFSEEVLTTGMILTHFLNELKKVQVMEGEEDFSVNQGDTGADADSKISSSPIIQLQTQVSSILAPFFTEDGLIAKCLDYSTTLEHIMDFTRLRALTSLFSMIKQSIRNMIEYNQSHSDFPLNNEQIENYVAKSLISSVVWSMSGDSKLKVREQLSQYIKNI----STVDLPTVGGIKNI-IDFEVNIQGTWVAWSNKVPQIEVETHKITATDVVVPTMDTVRHEALLYTWLAEHRPVLLCGPPGSGKTMTLFSALRCLP---DMEVVGLNFSSATTPELMLKTFDQYCEYRKTPNGIVLAPQQLNKWLIFFCDEINLPDMDKYGTQRVISFLRQMVEHHGFYRITDMQWVSFERIQFVGACNPPTDPGRKPLSHRFLRHVPVVYVDYPGETSLKQIYSTFNRAMLRMLPS-LRGYADTLTNAMVEFFLKTQERFTHDMQP-----HYIYSPREMTRWVRGIHEALKPLESLSVEGLVRIWAHEALRLFQDRLVEEDERHWTDDNINEVALKHFPNINKEEALK-RPILYSNWL--SKDYSAVTQEELRDYVKAR-LKVFYEEEL------DVPLVLFNQVLDHVLRIDRVFRQPQGHLLLIGVSGAGKTTLSRFVSWINGLSVFQVKVHNKYTAEDFDEDLRNVLRRSGCKGEKITFIMDESNVMDSSFLERMNTLLANGEVPGLFEGDELTTLMTQCKEGAIREGLMIDSQEELYKWFTQQICRNLHVVFTMNPSADGLKDKASTSPALFNRCVLNWFGDWSLEAYFQVGKEFTNRLDLERTDYKVPDTLPCIAEGLLPQNPIYRDVVVNALVFVHQTMHQANVRVQKRGGRTAAITPRHYLDLIAHYMKLSAEKRADLEEQQLHLNNGLKKIEQTVDQVEVMQRSLTKKRQELENMNEAANAKLKQMVQDQQEAEQKKTTGQA----LKEELAKQEQFVNEKQKTVKQELDQVEPTVNEAKQAVQNIRKKDIQEIKAMKNPPNAVKMAVESICLLLGEKTTDWQSILKVIIKDTFVTSILNFNTDDVSDNTRETMKKKYLSNPDYNFEKVNKASNACGPMVKWVLAQISYADILKRVEPLRNELTELSDAAEQNRKKSQETEDLIAQLEKSIAKYTEEYATLISQAQTIKSDLASVESKVGRSVALLGSLSSERTRWDSGSETFKAQMATINGDCLLSSAFMAYGGYFDQHMRTSLFNTWCHHLSEADILFRSDLARVEYLSNPDDRLRWQANSLPADDL-CVENAIILRRYNRYPLIIDPSGQATTFLLNEYKEKKITKTSFLDDSFRKTLESALRFGTPLLVQDV-ESYDPILNPVLNREVRRTGGRTLITLGDQDIDLSPTFTIFLSTRDPSVEFAPDICSRVTFVNFTVTRSSLQNQCLNAVLKIERPDIDQKRSDLLKAQGEFQLKLRHLEKDLLQSLNEAQGNLLENDKIIARLETLKREAADVAKKVEETDVVMQEVESVSTEYVPLAQSCSNIYFTLEAMNQIHFLYQYSLQLMLDIFSSVLINNPELTNVKAASDRLKIITKNLFQVTYNRLARGMLHEDQITFATILARIFLKGSTPIGFLENEFQHFLRSQEATITSSDSNKQDNLGLTLH--------QDQIDSVKRLKKLKVFAKIEEKVKSTKDIKNWTLTVTPESNVPELWVDDNNYNDEKLSKIAKGMYNLLIIQAIRPDRLLASTQKFIASVLGDTFTESVRGTLDLASIVEVEVTACVPILLCAVQGYDPSGRVEDLASEQG--KQLTGIAIGSAEGFSQAEKAINSAAKTGKWVMLKNVHLATSWLVSLEKKIHSL-----QAHPNFRLFLTMEITPKLPVNLLRAGRVLVFEPPPGIKANLLRTLSSINNQRMSKE--PVERSRLYFLLAWLNAIVQERLRYVPLGYSKKYEFGESDFKCALDTIDTWVDGAAMGRTNLPPEKIPWVALQTLLGSCIYGGKIDNAFDQRLLNSFLGYLFTEKCFDHNFALVSDADDGSNIAFPESTKHT-DILQWVHKLPDLQTPSWLGLPNSAEKVLLTNLGQSLIGNILKMQQSLEDDEELVVGQSKTKRTI--EVGDGRPAWMRQLYQSTQTWLQILPKSVTPLQRTIENIKDPMYRCFEREVNSGCNLLASVRKDLEDVAEVCKGAKKPTNHHRSMMADLAKGIIPKMWIRYAIPPGLTVIQWIQDFADRIKQLLHISDTAAKSGVIALRSIQVWLGGLFMAEAYITATRQSVAQNNKWALEEL 13736 EL + Q + YP +E + + +Q+ +L++S +V Y N K +K P+ E+ A+ N A +Y T+ Y+ + Q ++ L A D + LE+ S + +K G ++ K++ + +K ++L K + K L Q A+ ELE + TN+ V +T+ I+ K++ E ++ + +++ D ++ P D + ++ +A + ++ + S + + ++ + EV + K + E + ++ L+GK +RL + + ++ + V+ E++ +EL +++WN L + +D ET + + P L ++ + +L + ++ L+ I L++ A+K+RHW + + N + E L LG + I+ ++ E I EV A E +LE L+++ + WK+ + L + SK I+ G DD+ + + + NV+++ S + W+ +L + D W+ QR W+YL+ IF+ + DI+ LP E++ F +V + +M+KV + P + L A LE + LL +IQK L YLE + FPRFYF+ +++LLEI+ +++ +Q H +K F + + +D+ V ILGM+S EGE++ +S IE + WL M LN+ K+IS + + ++ W Q + IT S + A S SL V LN LA V P + R L LI VH RD++ + N V S NF+W+ Q+R+Y+DP L + ++N+ + YG+EYLG RLV TPLTDRCYL + AL+ LGG+P GPAGTGKTE+ K L L + +VFNC E DF+ MGR F GL Q GAW CFDEFNR++ +LS ++QQ+ I+ A V+K E G+++ + P A FITMNPGYAGR+ LPDNLK LFR +AM P+ LIA+V+LYS+GF +++ LA K+ ++LC EQLS Q HYDFG+RA+KSVLV AG +KR L E +LI+++ ++ +PK +A D L ++LTD+FPG E + +L+ + K L A V+KV+QLY+ + HG+M+VGP+GSGKT +L L ++ + HI++PKS++ LYG ++ T EW DGL +R+ V+ + +WIV DG VD W+EN+N+VLDDNK+L L N ER+ + + ++FEVQDL A+ ATVSRCGMV+ L + ++ + ++ E ++ N D DA K +S Q QV D +++ + LF + + DF L+ ++ + + + +WS+ G+ E + +++ V +P G + + +DF+ W +P + + ++ D++VPT+DTVR L+ L+ ++ VL G G GK++ + L + + + +NFS+ T+ + + + E ++ I+ AP K ++ F D++N+P +D YG+Q I LRQ + GFY + W + AC PP GR P++ RFLRH + + E +L I+ + L P+ +R AD + A VE + R + D+ P HY+++ R++++ ++G+ +A P + R++ HEA R+FQDRL+ ++++ + + ++E+A KHF E + PIL+ +++ D + EEL D K + L Y ++ ++ LV F ++H+ RI R+ RQP+G+ LL+GV G GK +L+R ++ FQ+++ Y F EDL+ + +G KGE F+ ++ ++ FLE +N +L +GEVP LFE +E ++ + A G+ ++ ++ +F ++ NLH+V M+P D + + P+L N C ++WF +W EA V F +DL AEG+ +D V V +H ++ R R TP YL+LI Y+ + EKR L + + NGLKK+ +T D V+ MQ L +L+ + ++++ DQ+EA++ + QA KE+ + E QK +LD+ P + A++A+ ++ K DI E++ PP V +ESIC+LLG K DW S ++ F+ +++++ D + D+T + KKY+ NP + E V K S AC MV WV A YA + + VEP R +L E +E + +A++E IA+ Y I++ +T+ ++A +++ R+ L +L E+ RW F+ ++ + G+ +++A +AY G F R L N+W E + D + + L++P + +W ++ LP D L +E+ I+ R L + +A ++ + + + D++F +TLE+ +R G P+L+++V ES DP L P+L ++ GGR LI LGD DID F +++T+ + + P++C +VT +NFTVT+S L++Q L+ V+++ERPD++ +R+ L+ + +L+ +E +L+ L ++GN+L+++ +I L K + ++ +++E + +++ +Y P+A S +YF + ++ ++ +YQYSL+ +F++ + ++ + ++ RL+I+ N + Y +ARG+ +D++ F+ +L ++ I + E+ FLR + K D LT +D + S K K V A I S +++ + ++ P W D +L+ + L+ I+A + ++++ + F+ LG TF ES ++DL + E V+ +P++ G DP A + +++ I++G +G AEK I +A+K G WV L+N HLA SW++++E I L + H +FRLFL+ T PV +L+ + EPP G++AN R + V +L F + + +AI+QER ++ PLG++ KYEF +SD CAL+ + + L E IPW AL + G YGG++ + +DQR L + LG F+ K + N+ S I FP + D ++V LP P G+ +A T LI +L++Q L G KT I E+ D + L + + + + + + +EV+ NLL ++ L + + KG + + +P MW + P + W++D R + +I W+ G F + ++T T Q+ A+ +++L Sbjct: 282 ELLMEPQALLFYPGLEDFDEGLGEVTKRFQDAVLSVSNLVPDSYFDAFTRPIINGKVEEKTAGEGPSLATMFEDDRHLQGVIQSIRDAISNAFDMAWKYANTFEPYRKFY--QENESLDLEAIREGEHDVEFFATSLEKYNSEHEQAVGIMAKKPIGMILADLRKLKEVLIPSPLKCLEVINDILPKLAK---KRTDDLMKFCQDAQFELE---VVPSSTNDYVKSLTFLDEIQEKIDDIEAESMTIKELYDLI--DNYKVPTPPEDLAVYQTLRPTVTAVRNVIDKSLAERDSNIDKFCTCMDKDIVQLGKDVKEVKQKAQDPKILDSSSKSESIIAYLKELQGKMDRLHDTAFTYKSYQKNFK-----VEVTKFEELEEVHAELRLKQSLWNSLVEWDQSQQDWTETLFEELNPETLSNNVMKYAKTVMQLEKGLPPNSVVPILKEKLENMRHKLPVITNLRNPALKQRHWDQIQQIFNYHFKDEEPLTLGLLDKIEAFEHTESIEEVSGQASSEASLEGILKKVEDAWKSTEFIVLPHRDSKDVFILGGVDDIQAVLDDSMINVSTIAGSRHVGPIRPRVEEWQRQLYLFSETMDEWMTCQRNWLYLESIFS-APDIQRQLPAEAKMFMTVDKSWKEIMRKVNRLP---NALRAATQPGLLETFQNNNALLDQIQKCLEAYLESKCVIFPRFYFLSNDELLEILSQTRNPHAVQPHLQKCFDAIAKLEFGSTVQAPSTPQDQPVTPTGERRKMRYATNDILGMISPEGEKVSLGKVSYSHSIETLTLCFSWLKDMSNHP-------LNLH-KKISLFSSL------MYITW--SRSPQYI-----ITSSTTINALFPSHYSL---CIVFPMNLNNLAALVRGVLPKLTRNILGALITIDVHARDIVTGMVNAKVDSENNFEWIKQLRYYWDPD----LDNCVVRMSNSMYIYGYEYLGASARLVITPLTDRCYLCLMGALQLDLGGAPAGPAGTGKTETTKDLAKALAKQCVVFNCSEGLDFKMMGRFFSGLAQSGAWCCFDEFNRIDIEVLSVIAQQLLTIRNA----KVAKASRFMFE--GREIKLVPSCAAFITMNPGYAGRTELPDNLKALFRPMAMMVPNYALIAEVILYSEGFESSKNLARKMTQMYRLCSEQLSQQDHYDFGMRAVKSVLVMAGALKRSN---------------------PDLEEDVVLIRALRDSNLPKFLAADAILFRAILTDLFPGKEIPDHDYGKLQSTIEDCMVAKGL-------QAIPALVKKVIQLYETMIVRHGVMLVGPTGSGKTTNYMMLQDTLTSLHEQAEDSPYYLPVQTHILNPKSVTMGELYGEVNKLTMEWRDGLMALKVRQ---CVQETTPDHKWIVCDGPVDALWIENMNTVLDDNKMLCLANSERIKLNNTIHMLFEVQDLAVASPATVSRCGMVYMDPNELGWRPFVRSWMQKHSD-KMKEETREYLWNLFDHYVDAGLKFASKKCTQAMQQV----------------------------DISKVTTMCCLFD-------SFFFPAKGGPDFNLDPTKLHPLICTAFLFVFLWSIGGNLVETCNESFDTFTRDLFADTHDVRIPGSGDLYSYYVDFDTR---RMEPWEKIIPAFKYSS-EVPYFDLLVPTVDTVRFGFLMDKLLSVNKSVLYTGTTGVGKSVIAKAILDDISQKSNYMAIMMNFSAQTSSQRTQEMIETKLEKKR--KNILGAPA--GKRMVIFVDDLNMPKLDTYGSQPPIELLRQYQDFRGFYDREKLFWKEIHDMTICSACAPPGG-GRNPVTPRFLRHFSMFCIPSSAEHTLGHIFKSIVSGFLLDFPAEVRECADAIVGASVEIY----ARMSTDLLPTPAKSHYVFNLRDLSKCIQGVLQA-DPGVIRDKGQIFRLFCHEASRVFQDRLINKEDKTFFNTIMSEMAHKHFQQARSPEKFESNPILFGDFMKMGADPADKLYEELTDLKKVKNLLTDYLDDYNMNSSKEMKLVFFMDAIEHISRIARMVRQPRGNALLVGVGGTGKQSLTRLACHMSAYKCFQIELTRGYDYSAFREDLKKLYDVAGVKGENTVFLFTDTQIVVEEFLEDINNILNSGEVPNLFEPEEYEAVLNGTRPLAKEAGIPEGDRDGVFDYFISRVRNNLHIVLCMSPVGDAFRTRCRMFPSLVNCCTIDWFTEWPREALLSVSSNFFEEVDLG-------------AEGV-------KDKVAEMCVEIHTSVSTMADRFYAELRRRYYTTPTSYLELITLYLSMLDEKRKQLIGARDRVKNGLKKLLETNDLVDTMQVELVALEPQLKQKSLDVEKLMEKLQVDQEEADKVRNVVQAEEAVAKEKADETSAIAAEAQK----DLDEALPALEAAQKALDSLDKSDISELRVFTKPPELVMTVMESICILLGVK-PDWPSAKTMLGDAGFLKKLMDYDKDKIPDSTLRKL-KKYIDNPKFVVEVVEKVSKACRSMVMWVRAMDLYARVYRTVEPKRAKLAAAQAELEVVMSTLREKQASLAEVESKIAELQAAYDHSIAEKETLTKNIAQTAARLKRASKLTTALGDEQGRWTENVAAFELEIGNVVGNVFVAAACVAYFGAFTSLYRHELINSWIEQCKELGVPVSDDFSLINVLADPYEIRQWNSDGLPRDSLKAIEDRILKLLNMRSTLFL----KANRWIRTKEAKNGLKIIKLTDNNFLRTLENCIRIGMPVLLEEVGESLDPALEPILLKQTFVQGGRLLIRLGDSDIDYDKNFRFYMTTKLANPHYLPEVCIKVTIINFTVTKSGLEDQLLSDVVRLERPDLEDQRNQLIVRINSDKNQLKAIEDRILKLLFHSEGNILDDEVLINTLNESKVTSGVISTRLKEAERTEEKITIAREKYRPVATRGSVMYFVVASLAEVDPMYQYSLKYFKQLFNACIESSEKTDDL---DRRLEILLNNCTESVYVNVARGLFEKDKLVFSFMLCGDIMRQQEIIT--DEEWNFFLRGT-GGLDKERPAKPDVPWLTDFMWNTCCDLEDVLHSFKGFKGDFVKAPI---TISMGNLQQSEVGDDDQAEKPRSWQD-------RLTSFER----LIFIKAFKEEKVVFAAVDFVCENLGKTFVES--PSIDLPVLFE-NVSNMIPLIFILSTGSDPMNAFLRFARDMNYTERIQAISLGQGQG-PVAEKLIANASKNGDWVFLQNCHLAASWMLAMETTIKDLTNNEAEVHEDFRLFLSSMPTKAFPVTVLQNSVKVTNEPPKGLRANTKRAFGELMADPFESHVLGVRWRKLVFGICFFHAIIQERKKFGPLGWNIKYEFNDSDRMCALENLKMF----------LVDENIPWDALTFITGQITYGGRVTDEWDQRCLTTILGRFFSPKILEDNYKFSE-----SGIYFPPGFESLHDYREYVDNLPLTDEPEVFGMHENANIAFQTQETHQLIYTVLEVQPRLASS-----GGGKTNDEIVYELADS-------ILGKLMDVLDMEKAEKSLFETDAKGRYNSLTTVLGQEVDRFNNLLKVIKNSLTQLQKAIKGLVVMSLELDKVYTSFLNNQVPDMWANSSYPSLKPLGSWVKDLVLRT--------MFVEQWIIHGPPKSFWISGFFFPQGFLTGTLQNHARKYNLPIDQL 3752
BLAST of Cytoplasmic dynein 1 heavy chain 1 vs. Ensembl Nematostella
Match: EDO34077 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SQG6]) HSP 1 Score: 1347.8 bits (3487), Expect = 0.000e+0 Identity = 921/3306 (27.86%), Postives = 1657/3306 (50.12%), Query Frame = 3 Query: 3255 YVKTWTNYQSLWDLQGDQLFSLIADDNTVWMNVLEEIK---SMRKHFDVAETQKEFGPLVIAFGKVQSKVSMKYDNWHKEVLTKFGQNMGKMMTTLYNEVQRARNELEQ--QSIDSGGTNESVNFITYTQNIKRKMNTWEKQAEACRAGQNILCRDRFQFPND---WLDSENIQGEWSAFKEIMRRKQETISSQVASLQMKITEEDKIVESKTTEVLGNWEKDKPIAGDLTPEEAVNIIQILEGKFNRLKEERENVQKAKEALELTEIGVKPISE-EKVTNALSELHDLKNVWNELKSIWEKIRDMKE--TPWLSVQPRKLRQDIENLTAQLKELPNSFKQYASFEHVRTLLKMYMKVNASIVELKSEAIKERHWRMLMRKLNVSW--SLNELQLGKVWDIDLVKNEEIIREVLAIAQGEKALEEYLRQITEVWKNYVLELTNYQSKSKI-IKGWDDLFNKVKEHINNVTSMKASPYFKQFEEEATAWEDRLNKINALFDVWIDVQRRWIYLDGIFAGSADIKVLLPVESQRFQSVSTEFLGLMKKVQKSPLVTDVLNIANVQRQLERLADL---LGKIQKSLGEYLERQRSSFPRFYFVGDEDLLEIIGNSXXXXXXXXXXXXMFAGVHSIILSE-----DEKVILGMMSKEGEELRFISPVSIIEHPRINDWLTAMEKEMRVSLA---KYLNVAVKEISGWRTESNIDKDKFMVWLDKYQAQIVVLAAQITWSEAVEASLASGVSLESTMTVVH------STLNMLADTVLYEQPPVRRRKLEHLIIEYVHQRDVLRALHNDGVSSNKNFDWMSQMRFYFDPKQTDPLHQLSIHVANAKFHYGFEYLGVCDRLVQTPLTDRCYLTMTQALEARLGGSPFGPAGTGKTESVKSLGNQLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLSAVSQQIQGIQEALRELMVSKKDSINVELLGKQVHVNPDMAIFITMNPGYAGRSNLPDNLKKLFRSLAMTQPDRQLIAQVMLYSQGFRTAEVLAGKVVPFFKLCDEQLSPQSHYDFGLRALKSVLVSAGNVKRDRIKQEKEKIVARGEEINETAIAEQLPEQEILIQSVMETMVPKLIADDIPLLYSLLTDVFPGVEYRQAEMKRLREELRKVSENKFLVYSDEPNTAGYLWVEKVLQLYQITTIHHGLMMVGPSGSGKTMACRVLLQALENI--DGIEGVAHI----IDPKSISKDSLYGYMDPNTREWTDGLFTHILRRIIDSVRGESNKRQWIVFDGDVDPEWVENLNSVLDDNKLLTLPNGERLAIPPNVRIMFEVQDLKYATLATVSRCGMVWFSEEVLTTGMILTHFLNELKKVQVMEGEEDFSVNQGDTGADADSKISSSPIIQLQTQVSSILAPFFTEDGLIAKCLDYSTTLEHIMDFTRLRALTSLFSMIKQSIRNMIEYNQSHSDFPLNNEQIENYVAKSLISSVVWSMSGDSKLKVREQLSQYIKNISTVDLPTVGGIKNIIDFEVNI-QGTWVAWSNKVPQIEVETHKITATDVVVPTMDTVRHEALLYTWLAEHRPVLLCGPPGSGKTMTLFSALRCLPDMEVVGL---NFSSATTPELMLKTFDQYCEYRKTPNGIVLAPQQLNKWLIFFCDEINLPDMDKYGTQRVISFLRQMVEHHGFYRITDMQWVSFERIQFVGACNPPTDPGRKPLSHRFLRHVPVVYVDYPGETSLKQIYSTF-NRAMLRMLPSLRGYADTLTNAMVEFF-------LKTQERFTHDMQPHYIYSPREMTRWVRGIHEALKPLESLSVEGLVRIWAHEALRLFQDRLVEEDERH----WTDDNINEVALKHFPNINKEEALKRPILYSNWLSKDYSAVTQEELRDYVKARLKVFYEEELD----------VPLVLFNQVLDHVLRIDRVFRQPQGHLLLIGVSGAGKTTLSRFVSWINGLSVFQVKVHNKYTAEDFDEDLRNVLRRSGCKGEKITFIMDESNVMDSSFLERMNTLLANGEVPGLFEGDELTTLMTQCKEGAIREGLMIDSQEELYKWFTQQICRNLHVVFTMNPSADGLKDKASTSPALFNRCVLNWFGDWSLEAYFQVGKEFTNRLDLERTDYKVPDTLPCIAEGLLPQNPIYRDVVVNALVFVHQTMHQANVRVQKRGGRTAAITPRHYLDLIAHYMKLSAEKRADLEEQQLHLNNGLKKIEQTVDQVEVMQRSLTKKRQELENMNEAANAKLKQMVQDQQEAEQKKTTGQALKEELAKQEQFVNEKQKTVKQELDQVEPTVNEAKQAVQNIRKKDIQEIKAMKNPPNAVKMAVESICLLLGEKTTDWQSILKVIIKDTFVTSILNFNTDDVSDNTRETMKKKYLSNPDYNFEKVNKASNACGPMVKWVLAQISYADILKRVEPLRNELTELSDAAEQNRKKSQETEDLIAQLEKSIAKYTEEYATLISQAQTIKSDLASVESKVGRSVALLGSLSSERTRWDSGSETFKAQMATINGDCLLSSAFMAYGGYFDQHMRTSL-FNTWCHHLSEADILFRSDLARVEYLSNPDDRLRWQANSLPADDLCVENAIILRRYNRYPLIIDPSGQATTFLLNEYKEKKITKTSFLDDSFRKTLESALRFGTPLLVQDV-ESYDPILNPVLNREVRRTGGRTLITLGDQDIDLSPTFTIFLSTRDPSVEFAPDICSRVTFVNFTVTRSSLQNQCLNAVLKIERPDIDQKRSDLLKAQGEFQLKLRHLEKDLLQSLNEAQGNLLENDKIIARLETLKREAADVAKKVEETDVVMQEVESVSTEYVPLAQSCSNIYFTLEAMNQIHFLYQYSLQLMLDIFSSVLINNPELTNVKAASDRLKIITKNLFQVTYNRLARGMLHEDQITFATILARIFLKGSTPIGFLENEFQHFLRSQEATITSSDSNKQDNLGLTLHQDQIDSVKRLKKLKVFAKIEEKVKS-TKDIKNWTLTVTPESN-VPELWVDDNNYNDEKLSKIAKGMYNLLIIQAIRPDRLLASTQKFIASVLGDTFTESVRGTLDLASIVEVEVTACVPILLCAVQGYDPSGRVEDLASEQG--KQLTGIAIGSAEGFSQAEKAINSAAKTGKWVMLKNVHLATSWLVSLEKKIHSLQA---HPNFRLFLTMEITPKLPVNLLRAGRVLVFEPPPGIKANLLRTLSSINNQRMSK--EPVERSRLYFLLAWLNAIVQERLRYVPLGYSKKYEFGESDFKCALDTIDTWVDGAAMGRTNLPPEKIPWVALQTLLGSCIYGGKIDNAFDQRLLNSFLGYLFTEKC 12950 Y+ TW Y+ +W++Q D N + +I + +F ET +++ ++ + + W + T + + +T L N ++ +L +++D G +S++ + QN + E + IL + P + LD+ + GEW F++ + + + + + + + +++ P + + +EA+ + + LK + ++++ ++ + K + EK L ++ + W EL W K+ E T + Q + L + + + ++K+ K + + +++ ++ + + I +LK+ A+++RHW + ++ + + ++ L K+ ++ L + E I E+ A E ++E+ + I +W L++ Y+ + +K D++F +++++ +++MKAS Y K FE E WE L+ I + ++ + VQR+W+YL+ IF G DI+ LP ES F V+ + +M+++ K P + L + LE L D+ L +IQKSL YLE +R FPRFYF+ ++DLLEI+G SK+ + +Q H KK F + ++ ++ D+ +GM S EGE + F V ++E P + WL +E+ MR +L K+ + +K ++ S DK W+ ++ Q+ + ++Q+ W+ +L+S + S LN ++ + ++R K+ L+ VH RDV+ L G + F+W+SQ+R Y+D D + + N +F YG+EYLG RLV TPLTDRCY+T+T AL GGSP GPAGTGKTE+VK LG LG +V+V NC E DF++MGR++ GL Q GAWGCFDEFNR+ +LS V+QQI I AL + G+++++ IFITMNPGYAGR+ LPDNLK +FR ++M PD +IA+++L+++GF +VLA KV + L +QLS Q HYDFGLRAL SVL AG KR + ++EIL+ S+ + V KL D PL +++D+FPG+E + +LR + V+E K Y PNT + K++QLY+ H ++VG +GSGK++ RVL A+ + DG G + I+PK++S LYG D NT EWTDG+ + ++R+ + E + +WI+FD VD W+E++NSV+DDNK+LTL NGER+++P V ++FEV+DL A+ ATVSRC GM+ T F D Q + D ++ + LQ + + K L++ H + L S+ S+ E N N E + + ++WS+ R+++ +++ + P + ++ V+I Q TW +W +K+ + +++PT+DTVR++ L+Y + RPVLL GP G+GKT L+ L D + GL N S+ T+ + + + E R + + +Q+ I F D+ N+P D +G+Q + +R +++ GF+ Q V + + + A P GR +S R ++ + +P E+ +K+I+ T N+ + ++ D +T A +E + L T R HY+++ R++++ +G+ A K L + R+W HE R+F DRL++ +R D + + F N+ K+ ++ N++ D E+L D+ KA +K + E++++ + LVLF ++HV RI RV QP+G++LL+G+ G+G+ +L+R S+I VFQ++V Y ++F +DL+ + ++G + F+ +++ ++ FLE +N +L++GEVP L++ DE + T + A +E + D+ E ++ +F +++ NLH+V M+P D +++ PA N ++WF +W +A +V + + ++L + K V V VH+++ + R+ R +TP +YL+L++ Y L AEK+ +L + L NGL KI+ T +VEVM L ++ + L +VQ ++EA++++ QA E++A +E + + +LD+ P + EA +A++++ KKD+ EIK+ PP V+ +E++ +L + T W + + F+ ++N++ D+++D + + Y + PD+ E + + S A + WV A Y I + VEP + L + + E+ + E + + ++ + + +Y +Q + +++ +E K+ R+ L+ L+ ER RW++ + + + GDCL+++AFM+Y G F + R L TW + + + + + +L+ P W LP+D EN +++ R NR+PL+IDP GQA ++ N + + + +TLE+A++FG+P+L+Q+V E DP L P+LN+ V + GGR LI LGD++++ SP F +++T+ + + P+I ++ T VNF V L+ Q L V++ ERP++++++ L+ + KL LE ++L+ L AQG+LL++++++ L + K + +VA+++ ++ ++++ Y P AQ S ++F L M +I +YQ+SL +D+F++ + + N+ +R++ + + Y RG+ ++ F+ + L+ + + +E+ FLR + + + L D+V L KL F I + +D W + PE+ +P W +N N+ + +L+++++RPDR+ + FI + LG F E LD++S+V+ + + P++ G DP+ + LA G + +++G + A + I K G WV L N HL+ SW+ L+K + LQ HP+FRL+L+ P+ P+++L+ G + EPP G+KAN+ R I Q+ S+ + + +L F L + ++++ ER +++ LG++ Y F +SDF+ + + + ++D E+ PW AL+ L+ YGG + + FD+RLL+S++ +F ++ Sbjct: 775 YLSTWDGYREIWEIQKDAFIRRYQRLNPPVSSFDADIARYTEIANNFQKEETVLNIDFVLLDCSPLKFALLSHCNEWQNKFTTLLREMASQKLTELNNFLKGNAKKLSAPPETLDELG--DSLSLLEQLQN---DLPNIEAKFAPLHQQFAILEKYEVAIPEEVQGMLDA--LSGEWLLFQQCLIDSDVMLKKSKEKFKTGLIHSSEEFKKTVNGLFDDFQSKGPFSSSIGVKEALEQVTQYHEQVVNLKSQETSLRRGLNIFKIEQALSKDLQNLEKDLEHLEQVWTVTKEWEELWDTW-KVGKFVELVTTDMETQAQLLFKRLNKIIREVKD-----KNWEICDSIKSRIEQFKRTMPLIQDLKNSAMRDRHWSQIKTEVQKPFDHTGDDFTLEKIIELGLDQFGEQICEISGAASKELSIEQAISGIASIWDQVSLDIGPYKDRGHFRLKQTDEVFQQLEDNQVTLSTMKASRYVKAFEAEVDKWERTLSLILEVVEMILTVQRQWMYLENIFLGE-DIRKQLPRESAEFDDVNANWKIIMQRLNKDP---NALRGTHYPGLLETLNDMNTKLEEIQKSLDMYLETKRQIFPRFYFLSNDDLLEILGQSKNPEAVQPHLKKCFDNIKTLKMARVGLTFDKTEAVGMYSAEGEYVEFGHSV-LLEGP-VEAWLCDVERSMRWTLKELLKHCRLGLK-----KSLSKRDK-----WVKEWPGQLTITSSQMQWTSDCNKALSSSKERGDKKALKSLKKKQVSMLNKFSEMIRGSLTKMQRLKIVALVTIEVHGRDVIEKLIKAGCNDVTAFEWLSQLRLYWDKDIDDCV----VRQTNTQFQYGYEYLGNSGRLVITPLTDRCYMTLTTALHLHRGGSPKGPAGTGKTETVKDLGKALGNYVIVVNCSEGLDFKSMGRMYSGLAQTGAWGCFDEFNRINIEVLSVVAQQILSILSAL------SAGATRFVFEGREINLVWSCGIFITMNPGYAGRTELPDNLKSMFRPISMCVPDSGMIAEIILFAEGFNNTKVLAKKVHTLYTLAVQQLSKQDHYDFGLRALTSVLRYAGRKKRAN---------------------PDMSDEEILLLSMKDMNVAKLTTQDAPLFNGIVSDLFPGIEAPVIDYGKLRNAI--VAELKDGGYQPTPNT-----ILKIIQLYETKNSRHSTIVVGQTGSGKSVTWRVLQSAMTRLKRDGEPGFNVVREFPINPKAVSLGELYGEFDLNTNEWTDGVLSSVMRQ---TCSDEKPEEKWILFDAPVDTLWIESMNSVMDDNKVLTLINGERISMPDMVSLLFEVEDLAVASPATVSRC------------GMVYTDF-------------RDLGW-QPYVDSWLDRRVDKQSVEHLQRLF----------EKFVPKVLEFRK--HHCKEPVPTSELNSVVSLCVLFDALATEENGVRMS---NGESYARMLELWFLFCLIWSVCASVDEDSRKKMDNFLRELEG-QFP---AKDTVYEYHVDIKQKTWASWEDKLRSGWRYNPSVPFYKIMIPTVDTVRYDFLVYNLIQAKRPVLLTGPVGTGKTSVAQKVLQKL-DPKTYGLLVINMSAQTSSNDVQEIIESKVEKRTKGVYVPIGGKQM----ITFMDDFNMPAKDTFGSQPPLELIRLWIDY-GFWYDRMKQTVKYVKDMHLLASMGPPGGGRMVISKRLQSRFNLINMTFPQESQIKRIFGTMINQKLQDFEEDVKPLGDIMTQATIEIYNTIVAKMLPTPTRI------HYLFNLRDISKIFQGLLRANKDLHDTKT-AISRLWVHECFRVFSDRLIDNTDRESFVTLLSDKLGSMFDLTFHNLCPN---KQSPIFGNFMKDD---TMYEDLVDF-KA-IKRYMEDQMEDYNMEPGVIAINLVLFRDAIEHVTRIVRVIGQPRGNMLLVGIGGSGRQSLTRLASYIIEYKVFQIEVTKHYRRQEFRDDLKRLYYQAGVDNKPTVFLFNDTQALEEGFLEDVNNILSSGEVPNLYKPDEFEEVRTALSDIAAKEDVQ-DTPESMFHFFIERVRSNLHIVLCMSPVGDPFRNRIRMYPAFVNCTTIDWFSEWPGDALLEVAERYLENIELGDEETKAN--------------------VAQIFVTVHRSVVDMSARMLLELKRHNYVTPTNYLELVSGYQSLLAEKKKELGDAASKLRNGLDKIDDTRAKVEVMSVELEDATLKVAEFQKQCEEYLVVIVQQKREADEQQKMVQARSEKIAIEEDKCRVMAENAQHDLDEAIPALQEAMKALESLNKKDMTEIKSYGRPPALVEKVMEAVMILRQSEPT-WAEAKRQLGDGNFIKQLVNYDKDNMTDRILKKIGT-YCAQPDFQPEIIGRVSLAAKSLCMWVRAMEVYGRIYRVVEPKKQRLHQATAQLEEKQAILAEAKAKLKEVTDRMEELKRQYDEKSAQKEELRAKAELLEIKLDRAGKLVSGLAGERDRWEASVTILEENIGYLVGDCLIAAAFMSYAGPFLSNYRDELVLKTWLAQVRQLGVACNPNFSFSGFLAKPTTVREWNIQGLPSDAFSTENGVMVTRGNRWPLMIDPQGQALKWIKNMEGKSGLKIIDLQQSDYLRTLENAVQFGSPVLLQNVQEELDPSLAPILNKSVVKVGGRYLIKLGDKEVEYSPDFRFYITTKLSNPHYTPEISTKTTIVNFAVKEQGLEAQLLGIVVRRERPELEEQKDALVINIAAGKKKLEELEDEILRLLQTAQGSLLDDEQLVNTLNSSKTTSQEVAEQLTVSEQTEIKIDAAREGYRPCAQRASILFFVLNDMGRIDPMYQFSLDAYIDLFNNSIEKSQRSPNL---DNRIQNLNEYHTYAVYKYTCRGLFERHKLLFSFQMCSKILEAAGKLNM--DEYNFFLRG--GVVLDREGQMDNPCTQWLTDTSWDNVTELDKLPNFHGIVTSFEQYPRDWNQWYTSSEPENTPLPGEW--ENACNE---------LQRMLVVRSLRPDRVSFTATSFIVNNLGSKFVEP--PVLDMSSVVD-DSSTRTPLIFVLSPGVDPTSALLQLAENCGMSNRFHALSLGQGQA-PIATRMIKEGVKDGNWVFLANCHLSLSWMPQLDKLVEQLQVEDPHPDFRLWLSSSPHPEFPISILQVGIKMTTEPPKGLKANMKRLYQLITEQQFSRCHKQDKYKKLLFGLCFFHSVLLERRKFLMLGWNIVYGFNDSDFEVSENLLSIYLDEY---------EETPWDALKYLVAGVNYGGHVTDDFDRRLLHSYINEMFNDQA 3890
BLAST of Cytoplasmic dynein 1 heavy chain 1 vs. Ensembl Nematostella
Match: EDO47920 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RKK0]) HSP 1 Score: 1322.76 bits (3422), Expect = 0.000e+0 Identity = 1131/4499 (25.14%), Postives = 2103/4499 (46.74%), Query Frame = 3 Query: 1155 LKKVRATKYPV-NRIIK-LMEAL--SRDLTTQLMKVISNMHLMS-MPYDEFEKIFTACQQVFST-WEDE------------YDKMQNLLRDIAKKKREEFTKFAWKMNATHKKLQTRLENIKKFRYQHEQLRQVIVRVLKPVTKVVP----------SVEAGVPKDQITDKGDKSSTFLP----ESADTSSIDEVNAAYEIVKVIDCLD--FAKEENDEWDAA----------IKRYEERIDRVESRIASHLRDLLGQSKNANEMFRYFSRFNALFVRPHIRGAIGEYQTQLIQRVKDDIEALHNKFKVQYASSTACKMSKV-----RDLPPVSGSIIWVRQILRQLNAYMKRVEDVLGKDWAQHIEGQKL--KADGESFKLKLNTSELFEEWSKKVAEKSLSVAGSIFNVESTRTVVTVRDREPQKITVLKLKVNFLPDVITLAKEVRNMRALGFRTPLSIVNKAHSA----NQLYPFAISLIESVRTYESTCSKIEEHKMQ-NISLLTAGLRK-DVQLCIHEGVQITWESYRLDQYVQKLAELVFSFQEKVDDLVIVIKEID-FNVKALETCSYN-KQTFEEILIRIQEAVDNMSLHQFSNLAQWVSNLDSLVEQRL-IVRLEAGLLEWIK--------VLKGXXXXXXXXXXXXXXXVNSMAKHRLGGKPQIKKLIHELRITNQQMHLYPSIEVATQDILYQMSSWQNIILNLSRIVHSRYQVGLETESDNQKTYKKLLSSLPNSGESLENAYAAVHNILRDANEYVKTWTNYQSLWDLQGDQLFSLIADDNTVWMNVLEEIKSMRKHF--DVAETQKEFGPLVIAFGKVQSKV-----SMKYDNWHKEVLTKFGQNMGKMMTT--------LYNEVQRARNELE----------QQSIDSGGTNESVNFITYTQNIKRKMNTWEKQAEACRAGQNILCRDRFQFPND-WLDSENIQGEWSAFKEIMRRKQETISSQVASLQMK----ITEEDKIVESKTTEVLGNWEKDKPIAGDLTPEEAVNIIQILEGKFNRLKEERENVQKAKEALELTEIGVKPISEEKVTNALSELHDLKNVWNELKSIWEKIRDMKETPWLSVQPRKLRQDIENLTAQLKELPNSFKQYASFEHVRTLLKMYMKVNASIVELKSEAIKERHWRMLMRKLNVSWSLNE-LQLGKVWDIDLVKNEEIIREVLAIAQGEKALEEYLRQITEVWKNYVLELTNY-QSKSKIIKGWDDLFNKVKEH-INNVTSMKASPYFKQFEEEATAWEDRLNKINALFDVWIDVQRRWIYLDGIFAGSADIKVLLPVESQRFQSVSTEFLGLMKKVQKSPLVTDVLNIANVQRQLERLADLLGKIQKSLGEYLERQRSSFPRFYFVGDEDLLEIIGNSXXXXXXXXXXXXMFAGVHSIILSEDE-----KVILGMMSKEGEELRFISPVSIIEHPRINDWLTAMEKEMRVSLAKYLNVAVKEISGWRTESNIDKDKFMVWLDKYQAQIVVLAAQITWSEAVEASLASGVSLESTMTVVH-------STLNMLADTVLYEQPPVRRRKLEHLIIEYVHQRDVLRALHNDGVSSNKNFDWMSQMRFYFDPKQTDPLHQLSIHVANAKFHYGFEYLGVCDRLVQTPLTDRCYLTMTQALEARLGGSPFGPAGTGKTESVKSLGNQLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLSAVSQQIQGIQEALRELMVSKKDSINVELLGKQVHVNPDMAIFITMNPGYAGRSNLPDNLKKLFRSLAMTQPDRQLIAQVMLYSQGFRTAEVLAGKVVPFFKLCDEQLSPQSHYDFGLRALKSVLVSAGNVKR-DRIKQEKEKIVARGEEINETAIAEQLPEQEILIQSVMETMVPKLIADDIPLLYSLLTDVFPGVEYR-------QAEMKRLREELRKVSENKFLVYSDEPNTAGYLWVEKVLQLYQITTIHHGLMMVGPSGSGKTMACRVLLQALENIDGIEGVAHIIDPKSISKDSLYGYMDPNTREWTDGLFTHILRRIIDSVRGESNKRQWIVFDGDVDPEWVENLNSVLDDNKLLTLPNGERLAIPPNVRIMFEVQDLKYATLATVSRCGMVWFSEEVLTTGMILTHFLNELKKVQVMEGEEDFSVNQGDTGAD--ADSKISSSPIIQLQTQVSSILAPFFTEDGLIAKCLDY-STTLEHIMDFTRLRALTSLFSMIKQSIRNMIEYNQSHSDFPLNNEQIENYVAKSLISSVVWSMSG----DSKLKVREQLSQY-IKNISTVDLPTVGGIKNIIDFEVNIQGT-WVAWSNKVPQIEVETHKITATDVVVPTMDTVRHEALLYTWLAEHRPVLLCGPPGSGKTMTLFSALRCL-PDMEVVG-LNFSSATTPELMLKTFDQYCEYRKTPNGIVLAPQQLNKWLIFFCDEINLPDMDKYGTQRVISFLRQMVEHHGFYRITDMQWVSFERIQFVGACNPPTDPGRKPLSHRFLRHVPVVYVDYPGETSLKQIY----------STFNRAMLRMLPSLRGYADTLTNAMVEFFLKTQERFTHDMQPHYIYSPREMTRWVRGI----HEALK-PLESLSVEGLVRIWAHEALRLFQDRLVEEDERHWTDDNINEVALKHFPNINKEEALKRPILYSNWLS----KDYSAVTQ-EELRDYVKARLKVFYEEELDVPLVLFNQVLDHVLRIDRVFRQPQGHLLLIGVSGAGKTTLSRFVSWINGLSVFQVKVHNKYTAEDFDEDLRNVLRRSGCKGEKITFIMDESNVMDSSFLERMNTLLANGEVPGLFEGDELTTLMTQCKEGAIREGLMIDSQEELYKWFTQQICRNLHVVFTMNPSADGLKDKASTSPALFNRCVLNWFGDWSLEAYFQVGKEFTNRLDLERTDYKVPDTLPCIAEGLLPQNPIYRDVVVNALVFVHQTMHQANVRVQKRGGRTAAITPRHYLDLIAHYMKLSAEKRADLEEQQLHLNNGLKKIEQTVDQVEVMQRSLTKKRQELENMNEAANAKLKQMVQDQQEAEQKKTTGQALKEELAKQEQFVNEKQKTVKQELDQVEPTVNEAKQAVQNIRKKDIQEIKAMKNPPNAVKMAVESICLLLG-----EKTTDWQSILKVIIK-DTFVTSILNFNTDDVSDNTRETMKKKYLSNPDYNFEKVNKASNACGPMVKWVLAQISYADILKRVEPLRNELTELSDAAEQNRKKSQETEDLIAQLEKSIAKYTEEYATLISQAQTIKSDLASVESKVGRSVALLGSLSSERTRWDSGSETFKAQMATINGDCLLSSAFMAYGGYFDQHMRTSLFN-TWCHHLSEAD--ILFRSDLARVEYLSNPDDRLRWQANSLPADDLCVENAIILRRYNRYPLIIDPSGQATTFLL----NEYKEKKITKTSFLDDSFRKTLESALRFGTPLLVQDV-ESYDPILNPVLNREVRRTGGRTLITLGDQDIDLSPTFTIFLSTRDPSVEFAPDICSRVTFVNFTVTRSSLQNQCLNAVLKIERPDIDQ-KRSD----LLKAQGEFQLKLRHLEKDLLQSLNEAQGNLLENDKIIARLETLKREAADVAKKVEETDVVMQEVESVSTEYVPLAQSCSNIYFTLEAMNQIHFLYQYSLQLMLDIFSSVLINNPELTNVKA-ASDRLKIITKNLFQVTYNRLARGMLHEDQITFATILARIFLKGSTPIGFLENEFQHFLRSQEATITSSDSNKQDNLGLTLHQDQIDSVKRLKKLKVFAKIEEKVK-STKDIKNWTLTVTPES-NVPELWVDDNNYNDEKLSKIAKGMYNLLIIQAIRPDRLLASTQKFIASVLGDTFTESVRGTLDLASIVEVEVTACVPILLCAVQGYDPSGRVEDLASEQG-----KQLTGIAIGSAEGFSQAEKAINSAAKTGKWVMLKNVHLATSWLVSLEKKIHSLQ--AHPNFRLFLTMEI--TPK---LPVNLLRAGRVLVFEPPPGIKANLLRTLSSINNQ--RMSKEPVERSRLYFLLAWLNAIVQERLRYVPLGYSKKYEFGESDFKCALDTIDTWVDGAAMGRTNLPPEKIPWVALQTLLGSCIYGGKIDNAFDQRLLNSFLGYLFTEKCFDHNFALVSDADDGSNIAFPESTKHTDILQWVHKLPDLQTPSWLGLPNSAEKVLLTNLGQSLIGNILKMQQSLEDDEELVVGQSKTKRTIEVGDGRPAWMRQLYQSTQTWLQILPK--SVTPLQRTIENIKDPMYRCFEREVNSGCNLLASVRKDLEDVAEVCKGAKKPTNHHRSMMADLAKGIIPKMWIRYAIPPGLTVIQWIQDFADRIKQLLHISDTAAKSGVIALRSIQVWLGGLFMAEAYITATRQSVAQNNKWALEELFLDVELG-EGKVDSNT-----CVITGLRLMGSEIVDPRTLKLSTLIYKDID----ICRLKWIRVEKSQQLEGSSAKDKVCLPIYLNAARS-TVLFTLYFSTTDSSYDFYKRGVAI 14048 L+K +++ +P +I K ++ AL +RD+T L + + M + E KI A V W + ++ N++ ++A+ + F ++ ++K++ +EN FR E+ R+ I + T+V P ++ V + ++ + D +T + E + + I ++++V++ + + FA N +DA ++ ER+ ++ R+AS + + + +L RP I E++ ++ R+ E ++ KV Y C ++ +++P V+GS+ W ++ ++ M+ ++ L + E + K D + L + ++++ W++ V G+I + ++ VRD + I KVNF P ++++ +EV+ + T +I A + + F +L +V Y +K+ E + L+ + L D QL E + W S + +Y++K ++V +++V I+ ++ K E + K+ +E L+ ++E + ++ +++ + Q + L++ L + + +A W VL G + KH + K +H+ M PS++ Y + + I+ ++ ++ ++ ES++ Y+ + + + E ++ V+ I+ ANEY ++ +Y LW ++ N V EEI++ + + T ++F + + K+ ++V + +D W + F Q + ++ L + V + N+L Q+++ G N V + + +K + + ++ E + +L + P + + + +W+ K+I T+ QVA LQ I + + K E ++ K P A + + ++ L+ + E + E+ L E+ + + E+ LK +W+ + + I + K TPW + + + + +++ L + + F + + +K + ++ EL++ AI+ERHW+ LM+ V + +++ L + ++L E+ +R ++ A E +E+ L+++ W E + ++ ++K ++L ++++ + + ++ S Y F EE T+W+ +L+ +++ +W +VQR W +L+ IF GS DI+ LP +S+RF + +F L + K P V + N + +LE L + L +K+L EYLE +R +FPRFYFV DLL+I+ N ++ +H K+F + + ED+ K +GM SKEGE + F S ++ WL + MR ++ K + +V E WL + AQ+ + QI W+ E +A G E + S L+ L + ++ + R+K+ + VH RDV+ L V S + F W+SQ+R +D +Q+ H + ++ +A+F Y +EYLG RLV TPLTDRCY+T+TQ+L + G+P GPAGTGKTE+ K LG LG V VFNC E D+++ G I+ GL Q GAWGCFDEFNR+ +LS ++ Q++ IQ+A+R+ KK+ + G+ + + P + +FITMNPGYAGR+ LP+NLK LFR AM PD +LI ++ML ++GF A LA K + + LC E LS Q HYD+GLRA+KSVLV AG++KR DR Q PE ++L++++ + +PK++ DD+P+ L+ D+FP ++ +A +K+ +L+ E+ F++ K++QL ++ + H + ++GP+G+GKT R L + N + + ++PK+++ D L+G+++P TREW DGLF+ I+R D S+ +WIV DGD+DP W+E+LN+V+DDNK+LTL + ER+ + P++R++FE+ LK AT ATVSR G+++ +N D G + S I + ++Q++ +++ F D + CLD + I + +T+L +++ + +++ N E E Y + + VW+ G D + R + S++ + T+ P+ G + D+ ++ + +V W++KV + E++ ++ V+V T +T R + + RPV+L G G+GKT+ + + L PD+ +VG + F+ TT ++ + ++ E + N P NK LI+F D++N+P +D YGT + + +RQ +++ ++ T + Q++ NP G ++ R RH V + +PG +LK IY F A+ + + A + + FL T +F HY+++ R+++ +GI HE +K P++ R+W HE R+++D+L+++ + D ++ K F +++E +P ++S++ S Y AV E L + L+ + E + LVLF + HV RI+R+ P+G+ LL+GV G+GK +L+R ++I+ L VFQ+ + Y D DL N+ ++G K F++ ++ V + +FL +N LLA+GE+PGL+ DE+ +++ + GL D++E + +F +++ RNL VV +P L+ ++ PA+ N ++WF +W EA V + F L+ +YK P V + +VH ++++ + R TP+ +L+ I Y L +K +L ++ L NGL K++ T QV+ ++ L + EL+ NE A+ ++++ + ++ ++K ++++ + V+EKQ++ +++L + EP + A++A+ + K ++ E+K+ +PP AV ++ +LL K W++ ++ K D F+ ++N++ +++ ++ + + + YL NP++ + + S A G + WV+ + + I VEP R L + +K + + I +L++++A+ T + S+ + + S + + L+G L+SE RW ++FK Q T+ GD LL++AF++Y G F + R +L N W L+ + I L + L++ W +LPAD + ENA IL R+PL+IDP Q ++ N+ + ++ + +LD T+E A+ G +L++++ E+ DP+L+ ++ R + G I +GD++++ F + L T+ + + P++ ++ T +NFTVTR L++Q L V+ ERPD+++ K SD L + Q F +KL+ LE LL L+ A GN L + ++ LE KR AA++ +V E ++ Y P A S +YF L +N+I+ +YQ+SL+ +F + VKA + + IT ++F T RG+ +D+I F +A L I + +E LR +S + NL +K L ++ F ++ ++ S K K + + PE P+ W K + L +++A+RPDR+ + F+ LG + E ++ E PI G DP VE + G K +++G + AE+ ++ AAK G WV+L+NVHL +WL LEKK+ + ++P++R++++ E TP +P +L + EPP G+ ANL + L++ N M E + F L + +A+V ER ++ P G+++ Y F D ++D + +++ A K+PW L+ L G +YGG I + +D+RL ++L + + L P ++ ++ + ++P GL +AE LT +L +L+MQ E G S+T+ ++ Q + LP+ +V + +E+ + P +E L ++ L+ + KG T+ + L +P+ W R A P + W D RIK+L + V VWL G F ++++TA QS+A+ N+W L+++ L V++ + K D N+ + GL + G+ D +T ++ KD+ + ++ I V+K K+ P+Y R T ++ + T ++ + GVA+ Sbjct: 256 LEKTQSSYFPAFKKIFKDVVAALDEARDITLHLKPLRRQLEDMEQYDFSELHKILPAILHVCGLLWANSKFYCSAPRIIVLLQELCNMIIEMARTYLDPAEIFKSEIEEAYEKVKKAIENCMLFRDTFEENRKTISKFFAEGTEVKPWEFASEIVFTRLDKFVERLRVVE--DVFATAMEFGKLEKVEIAGIKGKMLSHQVVEIFEEFNELFAVFSNSTYDALEATNKEFVDDFNQFRERVADLDRRLASIVCQAFDDCASTESALKLLDCLGSLLDRPLIHADF-EHKYPILLRM---FEKELDQAKVIYDQQMECAQAEGAAPINKNMPNVAGSLKWSSELKERITKPMQALKLSLNHGTLETAEAMIIFNKYDEMNKLLDSHDEKIYQSWTEGV--------GNIAQQNLDKPLI-VRDPNTKLI-----KVNFDPKLVSVLREVKYLEVASNETLEAIPESATAIFARNETFHKFCANLDLTVAWY----NKVRETLLDVEFPLVESQLVAIDTQLEQAEK-SLNWNSDGVWEYIEKTRDMVHDLEKRVQAAKDNIEAMNQLMTKWSEAPLFERKEAKKEGLLNLEER-ETITNKRYAMITQSGEKIHKLLKNNLELFQADADTDMWRAYVDSIDDMVLDGFFNCIHCSLNYLLEHTD--LKHNANALFEAKLELHQ-----PDMVFIPSLDFGVTAGFYDLV--EGIVSDIYKMASLVKRLAEHNESEH---YEADVEDMLDLSEMRQDLMDRVNGIMNKANEYRSSFDSYSYLWLDDRNEFMRQFLLYNHVL--TAEEIEAHTEEGVPESPPTLEQFKDQIDTYEKLYTEVDEVDGTNIFDTWFRVDARPFKQALLNIIKRWSYMFKQHLIDHVTNSLNDLAGFIKVADVGLTQTVEEGDYNGLVAVMGHLMAVKDRQSATDEMFEPLKQTIELLKTYGQEMPEEVHTQLQELPEQWNNSKKIAV----TVKQQVAPLQASEVAIIRRKCGQFDIKQHEFREDFRKTAPFAFN-----SEDVYDRLDKSNREICAMEEEMNALSESAGLFEVNFPDYKQLRACR--REVILLKQLWDMIFVVLTSIEEWKFTPWAEIDVENMEMECKRFVKEIRSLDKEMRAWDGFTGLDSTVKNMVTSLRAVGELQNPAIRERHWQQLMQATKVKFVMDDDTTLADLLALNLHNFEDEVRGIVDKATKELGMEKVLKELDVTWSQMEFEHEEHVRTHIPLLKSSEELIETLEDNQVVQLQNLMTSKYIGHFLEEVTSWQKKLSTADSVITIWFEVQRTWSHLESIFIGSEDIRNQLPEDSKRFDGIDVDFKELTNEGAKIPNVVECCNRPGLFEKLENLQERLSLCEKALAEYLETKRLAFPRFYFVSSADLLDILSNGNQPVEVARHLSKLFDNMARLKFKEDDAGNVTKDAVGMYSKEGEYVEFDSVCDC--DGQVEIWLNRVMDRMRATVRKEQSESVVSYEEKPREQ---------WLFDFPAQVALCGTQIWWT--TEVGIAFGRLEEGYENAIKDYYKKQVSQLSTLINMLIGDLSKGDRQKIMTICTIDVHARDVVAKLIQQKVDSAQAFLWLSQLRHRWDDQQS---HCFA-NICDAQFKYSYEYLGNTPRLVITPLTDRCYITLTQSLHLTMSGAPAGPAGTGKTETTKDLGRALGIMVYVFNCSEQMDYKSCGNIYKGLSQTGAWGCFDEFNRISVEVLSVIAVQVKSIQDAIRD----KKERFIFQ--GEDICLVPTVGLFITMNPGYAGRTELPENLKALFRPCAMVVPDFELICEIMLVAEGFLEARALARKFITLYSLCKELLSKQDHYDWGLRAIKSVLVVAGSLKRSDR----------------------QRPEDQVLMRALRDFNIPKIVTDDVPVFMGLIGDLFPALDVPRKRDPDFEALVKKSVTDLKLQPEDSFIL--------------KIVQLEELLAVRHSVFVLGPAGTGKTQVIRSLNKTYMN-QKRKPMMFDLNPKAVTADELFGFINPATREWKDGLFSTIMR---DLSNIASDSPKWIVLDGDIDPMWIESLNTVMDDNKVLTLASNERVPLTPSMRLLFEIGHLKTATPATVSRAGILF--------------------------------LNFADVGWNPYVSSWIDTR---EVQSEKANLQILF---DKYVPVCLDLLRVRFKKITPIPDITMVTTLCYLLECLL------TPANTPPDCNKELYELY----FVFAAVWAFGGAMFQDQLVDYRTEFSKWWVTEFKTIKFPSAG---TVFDYYIDSETKKFVPWTDKVQKFELDP-EVPLQAVLVHTAETTRVRFFMDLLMENRRPVMLVGGAGTGKTVLVNDYFQSLDPDVSMVGNVPFNYYTTSAMLQQVLEKPLEKKAGRN---YGPPG-NKKLIYFIDDMNMPMVDTYGTVQPHTLIRQHLDYSHWFDRTKLTLKDIRNTQYIACMNPTA--GSFTINPRLQRHFAVFAISFPGLDALKTIYLSILNGHMKVHNFASAVSKFTEKVTDAALAMNQKVTSTFLPTAIKF------HYVFNLRDLSNIFQGILFATHECIKTPVD------FARLWMHECNRVYRDKLIDDKDMEVFDKIQIDMTKKFFEELDEEAMYAKPNMFSHFSSGIGEPKYLAVPDWEVLSKLLTEALENYNEVNAVMNLVLFEDAMQHVCRINRILESPRGNALLVGVGGSGKQSLARLAAFISALEVFQITLRKGYGIPDMKLDLANLCTKAGLKNIGTVFLLTDAQVPEENFLVLINDLLASGEIPGLYPDDEVENIISGVRNEVKGAGLQ-DTRENCWMFFIERVRRNLKVVLCFSPVGATLRVRSRKFPAVTNCTAIDWFHEWPQEALVSVSRRFIEDLEQLEAEYKPP--------------------VAEFMSYVHTSVNEESQMYLANERRYNYTTPKSFLEQINLYRNLLKKKSKELTQKTERLENGLLKLQSTAQQVDDLKAKLASQEVELKQKNEDADKLIQKVGVETEKVSKEKAIADDEEKKVQVIAKDVSEKQRSCEEDLAKAEPALLAAQEALNTLNKGNLTELKSFGSPPGAVVNVCSAVMVLLAPANKIPKDRSWKAAKIMMGKVDAFLDQLINYDKENIHESNLKAV-QPYLDNPEFEPDFIKGKSLAAGGICAWVINIVQFYYIFCDVEPKRKALEAANAELAAAEEKLSKIKAKIQELDENLAELTANFERATSEKLKCQQEAESTAKTIELANRLVGGLASENVRWGESVKSFKEQEKTLPGDVLLTTAFVSYHGCFTRRYRDNLLNDKWLVFLASQNPKIPITEGLDPLSLLTDNATIATWNNENLPADRMSTENATILTNCERWPLMIDPQLQGVKWIKTREGNDLRIVRLGQKGYLD-----TIERAVSNGECVLIENMGENVDPVLDALIGRNTIKKG--RAIKMGDKEVEYHADFRMILHTKLANPHYKPEMQAQTTLINFTVTREGLEDQLLADVVSKERPDLEETKASDRIFPLTQQQNAFTIKLKELEDSLLARLSAAGGNFLGDYALVENLEITKRTAAEIEVQVTEAKQTEIKINDAREAYRPAAARASLLYFILNDLNKINPMYQFSLKAFSVVFQKAIERAEPAEEVKARVVNLIDCITYSVFIYT----TRGLFEKDKIIFTAQVAFQVLLMKKEI--IPHELDFLLRFPAVMNVTSPVDFLSNLSW-------GGIKALSNMEEFRNLDRDIEGSAKRWKKFAESECPEKEKFPQEW------------KNKTALQKLCMMRALRPDRMTYAVSNFVEEKLGHKYVEDAPTPFAMSF---EESGPATPIFFILSPGVDPLKDVEAHGKKIGFTFDAKNFHNVSLGQGQEIV-AEQCLDLAAKEGHWVILQNVHLVKNWLPKLEKKLEAFSEGSNPDYRVYISAEPAGTPDAHIIPQGILETSIKITNEPPTGMMANLHKALNNFNQDTLEMCARENEFKSILFSLCYFHAVVAERRKFGPQGWNRSYPFNTGDLTISVDVLYNYLEANA---------KVPWTDLRYLFGEIMYGGHITDDWDRRLCKTYLEEYMKPEMLEGELNL------APGFPLPPNSDFKGYHLYIDETLPPESPYLYGLHPNAEIGFLTTTSDNLFRTLLEMQPRDAGGGE---GASQTRE------------EKVKQVLDDIFEKLPEEFNVPEMMARVED-RTPYTVVAFQECERMNMLTNEMKTSLKQLDLGLKGELTITSEMEDLSNALFLDDVPESWTRRAYPSMFGLAAWFVDLLLRIKELEQWTSDFCLPNV-------VWLSGFFNPQSFLTAIEQSMARKNEWPLDKMALQVDVTKKNKEDFNSPPREGAYVHGLFMEGARW-DTQTGMIADSKLKDLTPAMPVMFIRAIPVDK------QDTKNVYECPVYKTRQRGPTYVWNFFLKTRENPSKWTLAGVAL 4467
BLAST of Cytoplasmic dynein 1 heavy chain 1 vs. Ensembl Medaka
Match: dync1h1 (dynein, cytoplasmic 1, heavy chain 1 [Source:ZFIN;Acc:ZDB-GENE-030131-7050]) HSP 1 Score: 2027.68 bits (5252), Expect = 0.000e+0 Identity = 1018/1787 (56.97%), Postives = 1343/1787 (75.15%), Query Frame = 3 Query: 186 PCMLNDDESKSRKDYELFLSEPQNEECLTKFINDNQVTTLTIQQTKRXXXXXXXXXXXXKISNEVNFESNKSQTSIFIKNNQVIEADKTISSQLQVLSYCDGPPFETMHSLVCYGLLPYFXXXXXXXXXXXXXXXXXMVPSVEKKIAELEIGLLHLQQNIEIPEITLTPHPYVAHIIQEKLLQNKEARVSDFEDKFEDTQFLNQLQAGVNRWIKEIQKVTKLNRDPSTGTALQEISFWLNLEHSLDKIQEKRESLEVALTLAILKQAKRFHATTSFDTDTALSSAKIQVKDYNQLMKDFPINDLLSASQLDKISEALQQIFSHLKKVRATKYPVNRIIKLMEALSRDLTTQLMKVISNMHLMSMPYDEFEKIFTACQQVFSTWEDEYDKMQNLLRDIAKKKREEFTKFAWKMNATHKKLQTRLENIKKFRYQHEQLRQVIVRVLKPVTKVVPSVEAGVPKDQITDKGDKSSTFLPESADTSSIDEVNAAYEIVKVIDCLDFAKEENDEWDAAIKRYEERIDRVESRIASHLRDLLGQSKNANEMFRYFSRFNALFVRPHIRGAIGEYQTQLIQRVKDDIEALHNKFKVQYASSTACKMSKVRDLPPVSGSIIWVRQILRQLNAYMKRVEDVLGKDWAQHIEGQKLKADGESFKLKLNTSELFEEWSKKVAEKSLSVAGSIFNVESTRTVVTVRDREPQKITVLKLKVNFLPDVITLAKEVRNMRALGFRTPLSIVNKAHSANQLYPFAISLIESVRTYESTCSKIEEHKMQNISLLTAGLRKDVQLCIHEGVQITWESYRLDQYVQKLAELVFSFQEKVDDLVIVIKEIDFNVKALETCSYNKQTFEEILIRIQEAVDNMSLHQFSNLAQWVSNLDSLVEQRLIVRLEAGLLEWIKVLKGXXXXXXXXXXXXXXXVNSMAKHRLGGKPQIKKLIHELRITNQQMHLYPSIEVATQDILYQMSSWQNIILNLSRIVHSRYQVGLETE-SDNQKTYKKLLSSLPNSGESLENAYAAVHNILRDANEYVKTWTNYQSLWDLQGDQLFSLIADDNTVWMNVLEEIKSMRKHFDVAETQKEFGPLVIAFGKVQSKVSMKYDNWHKEVLTKFGQNMGKMMTTLYNEVQRARNELEQQSIDSGGTNESVNFITYTQNIKRKMNTWEKQAEACRAGQNILCRDRFQFPNDWLDSENIQGEWSAFKEIMRRKQETISSQVASLQMKITEEDKIVESKTTEVLGNWEKDKPIAGDLTPEEAVNIIQILEGKFNRLKEERENVQKAKEALELTEIGVKPISEEKVTNALSELHDLKNVWNELKSIWEKIRDMKETPWLSVQPRKLRQDIENLTAQLKELPNSFKQYASFEHVRTLLKMYMKVNASIVELKSEAIKERHWRMLMRKLNVSWSLNELQLGKVWDIDLVKNEEIIREVLAIAQGEKALEEYLRQITEVWKNYVLELTNYQSKSKIIKGWDDLFNKVKEHINNVTSMKASPYFKQFEEEATAWEDRLNKINALFDVWIDVQRRWIYLDGIFAGSADIKVLLPVESQRFQSVSTEFLGLMKKVQKSPLVTDVLNIANVQRQLERLADLLGKIQKSLGEYLERQRSSFPRFYFVGDEDLLEIIGNSXXXXXXXXXXXXMFAGVHSIILSEDEKVILGMMSKEGEELRFISPVSIIEHPRINDWLTAMEKEMRVSLAKYLNVAVKEISGWRTESNIDKDKFMVWLDKYQAQIVVLAAQITWSEAVEASLA--SG----VSLESTMTVVHSTLNMLADTVLYEQPPVRRRKLEHLI 5525 P +L +D ++ E L E E + KF+ D+Q+ T+ ++++K F S IK VI+ADK IS+Q++VL+ + P+ET+HS + + P+FKSYI++ GK M PSVEKKIAELE+GLLHLQQNIEIPEI+L H + +I ++ + ++ +V+DF DK ED FLNQLQ+GVNRWI+EIQKVTKL+RDP++GTALQEISFWLNLE +L++IQEKRES EV LTL ILK KRFHAT SFDTDT L A V DYN LMKDFP+NDLLSAS+LDKI +AL IF+H+KK+R TKYP+ R ++L+EA+SRDL++QL+KV+ LM + Y+EFEK+ AC +VF TWEDEY+K+Q LLRDI K+KREE K W+++ H+KLQ+RL+++++FR QHEQLR VIVRVL+P V +V+ P + + + K + L ++AD ++I+EVN AYE VK +D LD +KE + W+AA+KRY+ERIDRVE+RI + LRD LG +KNANEMFR FSRFNALFVRPHIRGAI EYQTQLIQRVKDDIE+LH+KFKVQY S ACKMS VRDLPPVSGSIIW +QI RQL AYMKRVEDVLGK W H+EG KLK DG+SF+ KLNT E+F++W++KV +++L V+G IF +E++R R R +LKLKVNFLP++ITL+KEVRN++ L FR PL+IVNKAH ANQLYPFAISLIESVRTYE TC K+EE +ISLL AGL+K+VQ + EG+ + WESY+LD YVQ+LAE VF+FQEKVDDL+++ ++ID V++LETC ++ +TF +IL R+Q+AVD+++LH +SNL WV+ LD +E+ L VRL+AGL W +VL+G+ + + D DT+ H+ GG P+IK ++HELRITNQ ++L P IE + +M +W+ IIL+L RI RYQVG+ E S+ +K Y+ L+ +P+ +LE AY AV +I+ + +YVK W YQ LWD+Q + +++ + +D T W +L +I+ R FD AET+K+FGP++I +GKVQSKV++KYD+WHKEVL+KFGQ +G+ M ++++ ++R +LEQ S+D+ T+++VNFITY Q +KRK+ +EK E R GQ +L + RFQFP WL +NI+GEW AF +IM+RK I QVA+LQMKI +EDK VE++TT++L +WEK KP+AG+L PEEA+ + I EG F RLK ERE +AKEALELT+ G+ SEE+V AL ELHDLK VW EL +WE+I MKE PW+SVQPRKLRQ ++ L QLK +QYAS+E V+ LLK Y+KVN ++ELKSEA+K+RHW+ LM++L+V+W L+EL LG++WD+DL KNE ++++VL +AQGE ALEE+L+Q L+L NYQ+K ++I+GWDDLFNKVKEHIN+V++MK SPY+K FEE+A +WED+LN+I LFDVWIDVQRRW+YL+GIF GSADIK LLPVE+QRFQS+STEFL LMKKV KSPLV DVLNI VQR LERLADLLGKIQK+LGEYLER+RSSFPRFYFVGDEDLLEIIGNSK++ KLQKHFKKMFAGV SI+L+ED +LG+ S+EGEE+ F + VSI EHP+IN+WLT +EKEMRV+LAK L +V E++ + + +D +++ W+D+YQAQ+VVL+ QI WSE +E++L SG ++ ++ V +TLN+LADTVL EQPP+RRRKLEHL+ Sbjct: 37 PLLL-EDGGEAPASLETALEEKSAVEQMKKFLGDSQIHTILVERSK-------------------CFYSVNGLA--LIKRTGVIDADKPISTQVRVLTLSEDSPYETLHSFISNAVSPFFKSYIRESGKADRDGDK-MAPSVEKKIAELEMGLLHLQQNIEIPEISLPIHATITNIAKQCYERGEKPKVTDFGDKVEDPTFLNQLQSGVNRWIREIQKVTKLDRDPASGTALQEISFWLNLERALNRIQEKRESPEVLLTLDILKHGKRFHATVSFDTDTGLKQAVETVNDYNPLMKDFPLNDLLSASELDKIRQALMAIFTHMKKIRNTKYPIQRALRLVEAISRDLSSQLLKVLGTRKLMHVAYEEFEKVMVACFEVFQTWEDEYEKLQVLLRDIVKRKREENLKMVWRLSPAHRKLQSRLDHMRRFRRQHEQLRAVIVRVLRPQ---VSAVQQHAPGETVEPEDMKVAGVLFDAADANAIEEVNLAYENVKEVDGLDVSKEGMEAWEAAMKRYDERIDRVETRITARLRDQLGTAKNANEMFRIFSRFNALFVRPHIRGAIREYQTQLIQRVKDDIESLHDKFKVQYPQSQACKMSHVRDLPPVSGSIIWAKQIDRQLTAYMKRVEDVLGKGWENHVEGLKLKQDGDSFRAKLNTQEIFDDWARKVQQRNLGVSGRIFTIETSRA----RGRTG---NMLKLKVNFLPEIITLSKEVRNLKWLSFRVPLAIVNKAHQANQLYPFAISLIESVRTYERTCEKVEERS--SISLLVAGLKKEVQALVTEGITLVWESYKLDPYVQRLAETVFNFQEKVDDLLLIEEKIDLEVRSLETCMFDNRTFSDILNRVQKAVDDLNLHSYSNLPIWVNKLDIEIERILGVRLQAGLKAWTQVLRGQVEDKADVDMDTEA---PQVGHKPGGDPKIKNVVHELRITNQVIYLNPPIEDCRYKLYQEMFAWKTIILSLPRIQSQRYQVGVHYELSEEEKFYRNALTRMPDGPAALEEAYNAVEDIVNEVEQYVKVWLQYQCLWDMQAENIYNRLGEDLTKWQGLLVQIRKARGTFDNAETRKDFGPVIIDYGKVQSKVNLKYDSWHKEVLSKFGQMLGQNMQDFHSQISKSRQDLEQHSVDTASTSDAVNFITYVQTLKRKIKQFEKNVELFRNGQRLLEKQRFQFPPSWLYIDNIEGEWGAFSDIMKRKDTAIQQQVANLQMKIVQEDKAVENRTTDLLNDWEKTKPVAGNLRPEEALQSLTIYEGNFGRLKVEREKCARAKEALELTDTGLLSGSEERVQVALEELHDLKEVWTELAKVWEQIDQMKEQPWVSVQPRKLRQSLDALLNQLKNFQARLRQYASYEFVQRLLKGYLKVNMLVIELKSEALKDRHWKQLMKRLHVNWVLSELTLGQIWDVDLQKNEMVVKDVLLVAQGEMALEEFLKQ---------LDLVNYQNKCRLIRGWDDLFNKVKEHINSVSAMKLSPYYKVFEEDALSWEDKLNRIMGLFDVWIDVQRRWVYLEGIFTGSADIKHLLPVETQRFQSISTEFLALMKKVTKSPLVMDVLNIQGVQRSLERLADLLGKIQKALGEYLERERSSFPRFYFVGDEDLLEIIGNSKNVAKLQKHFKKMFAGVSSILLNEDNTEVLGISSREGEEVLFKTAVSITEHPKINEWLTLVEKEMRVTLAKLLAESVNEVTSFNKGTAVDLSQYIQWIDRYQAQLVVLSTQIAWSENIESALTTISGGGDMTPMQEVLSNVQATLNVLADTVLMEQPPIRRRKLEHLV 1776
BLAST of Cytoplasmic dynein 1 heavy chain 1 vs. Ensembl Medaka
Match: dnah5 (dynein axonemal heavy chain 5 [Source:NCBI gene;Acc:101171908]) HSP 1 Score: 1299.65 bits (3362), Expect = 0.000e+0 Identity = 931/3434 (27.11%), Postives = 1671/3434 (48.66%), Query Frame = 3 Query: 3705 DRFQFPNDWLDSENIQGEWSAFKEIMRRKQETISSQVASLQMKITEEDK----IVESKTTEVLGNWEKDKPIAGDLTPEEAVNIIQILEGKFNRLKEERENVQKAKEALELTEIGVKPISEEKVTNALSELHDLKNVWNELKSIWEKIRDMKETPWLSVQPRKLRQDIENLTAQLKELPNSFKQYASFEHVRTLLKMYMKVNASIVELKSEAIKERHWRML--MRKLNVSWSLNELQLGKVWDIDLVKNEEIIREVLAIAQGEKALEEYLRQITEVWKNYVLELTNYQSKSKIIKGWD---DLFNKVKEHINNVTSMKASPYFKQFEEEATAWEDRLNKINALFDVWIDVQRRWIYLDGIFAGSADIKVLLPVESQRFQSVSTEFLGLMKKVQKSP-LVTDVLNIANVQRQLERLADLLGKIQKSLGEYLERQRSSFPRFYFVGDEDLLEIIGNSXXXXXXXXXXXXMFAGVHSIILSED-EKVILGMMSKEGEELRFISPVSIIEHPRINDWLTAMEKEMRVSLAKYLNVAVKEISGWRTESNIDKDKFMVWLDKYQAQIVVLAAQITWSEAVEASLASGVSLESTMTVVH----STLNMLADTVLYEQPPVRRRKLEHLIIEYVHQRDVLRALHNDGVSSNKNFDWMSQMRFYFDPKQTDPLHQLSIHVANAKFHYGFEYLGVCDRLVQTPLTDRCYLTMTQALEARLGGSPFGPAGTGKTESVKSLGNQLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLSAVSQQIQGIQEALRELMVSKKDSINVELL--GKQVHVNPDMAIFITMNPGYAGRSNLPDNLKKLFRSLAMTQPDRQLIAQVMLYSQGFRTAEVLAGKVVPFFKLCDEQLSPQSHYDFGLRALKSVLVSAGNVKRDRIKQEKEKIVARGEEINETAIAEQLPEQEILIQSVMETM-VPKLIADDIPLLYSLLTDVFPGVEYRQAEMKRLREEL-RKVSENKFLVYSDEPNTAGYLWVEKVLQLYQITTIHHGLMMVGPSGSGKTMACRVLLQALENIDGIEGVAHIIDPKSISKDSLYGYMDPNTREWTDGLFTHILRRIIDSVRGESNKRQWIVFDGDVDPEWVENLNSVLDDNKLLTLPNGERLAIPPNVRIMFEVQDLKYATLATVSRCGMVWFSEEVLTTGMILTHFLNELKKVQVMEGEEDFSVNQGDTGADADSKISSSPIIQLQTQVSSILAPFFTEDGLIAKCLDYSTTLEHIMDFTRLRALTSLFSMIKQSIRNMIEYNQSHSDFPLNNEQIENYVAKSLISSVVWSMSGDSKLKVREQLSQYIKNISTV--DLPTV--GGIKNIIDFEVNIQGTWVAWSNKVPQIEVETHKITA--TDVVVPTMDTVRHEALLYTWLAEHRPVLLCGPPGSGKTMTLFSAL-RCLPDMEV-VGLNFSSATTPELMLKTFDQYCEYRKTPNGIVLAPQQLNKWLIFFCDEINLPDMDKYGTQRVISFLRQMVEHHGFYRITDM-QWVSFERIQFVGACNPPTDPGRKPLSHRFLRHVPVVYVDYPGETSLKQIYSTFNRAMLRMLPSLRGYADTLTNAMVEFFLKTQERFTH---DMQP-----HYIYSPREMTRWVRGIHEALKPLESLSVEGLVRIWAHEALRLFQDRLVEEDERHWTDDNINEVALKHFPNINK---EEALKRPILYSNWLSKDYSAVTQE-ELRDY--------------VKARLKVF---YEEEL---DVPLVLFNQVLDHVLRIDRVFRQPQGHLLLIGVSGAGKTTLSRFVSWINGLSVFQVKVHNKYTAEDFDEDLRNVLRRSGCKGEKITFIMDESNVMDSSFLERMNTLLANGEVPGLFEGDELTTLMTQCKEGAIRE-GLMIDSQEELYKWFTQQICRNLHVVFTMNPSADGLKDKASTSPALFNRCVLNWFGDWSLEAYFQVGKEFTNRLDLERTDYKVPDTLPCIAEGLLPQNPIYRDVVVNALVFVHQTMHQANVRVQKRGGRTAAITPRHYLDLIAHYMKLSAEKRADLEEQQLHLNNGLKKIEQTVDQVEVMQRSLTKKRQELENMNEAANAKLKQMVQDQQEAEQKKTTGQALKEELAKQEQFVNEKQKTVKQELDQVEPTVNEAKQAVQNIRKKDIQEIKAMKNPPNAVKMAVESICLLLGEK-------------TTDWQSILKVIIKDTFVTSILNFNTDDVSDNTRETMKKKYLSNPDYNFEKVNKASNACGPMVKWVLAQISYADILKRVEPLRNELTELSDAAEQNR--KKSQETEDLIAQLEKSIAKYT---EEYATLISQAQTIKSDLASVESKVGRSVALLGSLSSERTRWDSGSETFKAQMATINGDCLLSSAFMAYGGYFDQHMRTSLFNTWCHHLSEADILFRSDLARVEYLSNPDDRLRWQANSLPADDLCVENAIILRRYNRYPLIIDPSGQATTFLLNEYKEKKITKTSFLDDSFRKTLESALRFGTPLLVQDV-ESYDPILNPVLNREVRRTGGRTLITLGDQDIDLSPTFTIFLSTRDPSVEFAPDICSRVTFVNFTVTRSSLQNQCLNAVLKIERPDIDQKRSDLLKAQGEFQLKLRHLEKDLLQSLNEAQGNLLENDKIIARLETLKREAADVAKKVEETDVVMQEVESVSTEYVPLAQSCSNIYFTLEAMNQIHFLYQYSLQLMLDIFSSVLINNPELTNVKAASDRLKIITKNLFQVTYNRLARGMLHED-QITFATILARIFLKGSTPIGFLENEFQHFLRSQEATITSSDSNKQDNLGLTLHQDQIDSVKRLKKLKVFAKIEEKVKSTKDI-KNWTLTVTPESNVPELWVDDNNYNDEKLSKIAKGMYNLLIIQAIRPDRLLASTQKFIASVLGDTFTESVRGTLDLASIVEVEVTACVPILLCAVQGYDPSGRVEDLASEQGKQLTGIAIGSAEGFSQAEKAINSAAKTGKWVMLKNVHLATSWLVSL-EKKIHSLQAHPNFRLFLTMEITPKLPVNLLRAGRVLVFEPPPGIKANLLRTLSSINNQRMSKEPVERSR-LYFLLAWLNAIVQERLRYVPLGYSKKYEFGESDFKCALDTIDTWVDGAAMGRTNLPPEKIPWVALQTLLGSCIYGGKIDNAFDQRLLNSFLGYLFTEKCFDHNFALVSDADDGSNIAFPESTKHTDILQWVHKLPDLQTPSWLGLPNSAEKVLLTNLGQSLIGNILKMQQSLEDDEELVVGQSKTKRTIEVGDGRPAWMRQLYQSTQTWLQILPKSVTPLQ-RTIENIK--DPMYRCFEREVNSGCNLLASVRKDLEDVAEVCKGAKKPTNHHRSMMADLAKGIIPKMWIRYAIPPGLTVIQWIQDFADRIKQLLHISDTAAKSGVIALRSIQVWLGGLFMAEAYITATRQSVAQNNK-WALEELFL 13742 ++++FP + E ++ + ++M R E + S++ +LQ K +E + +++ + +++KD P+ L P++ + + + + +F+ L + + G+ ++ +EL L+ ++ ++ E + + W ++ K+ ++ + + ++LP + K++ +F ++ + + + + + S+A+ RHW+ + + N+ +L + + D +K +E I ++ A E+ +E+ L+++ W N ++++ +++ D +L +++ + + S+ ++ Y F+ + W L+ + + + W+ VQ WIYL+ +F G DI LP E++ F S+ ++ +M + + P +V + + + L L + L QKSL YLE++R FPRF+FV D LLEI+G + D +Q H +F + S+ E IL + S+E E + P++ + WL A+ KE + SL + A I E + +L+ + AQ+ +L Q+ W+ E +L + M+ + + LN L D + V R K E LI +VHQRD+ L + + +F+W+ Q RFYF+ + +D +++I++ + F Y E+LG +RLV TPLTDRCY+T+ QAL +GG+P GPAGTGKTE++K +G LG++V+VFNC + DF+ +GRIF GL Q G+WGCFDEFNR+E +LS +QQI + + KKD + G V +NP+ IF+TMNPGYAGR LP+NLK FRS++M PDRQ+I +V L S GF LA K +KLC+EQLS Q HYDFGLR + SVL + G KR + IV R V++ M + KLI +D L SL+ D+FPG+E + L + +K+ E + + W KV+Q+Y+ + HG+M +GPSGSGKT ++L++A+ G ++PK+I+ ++G +D T +WTDG+F+ + R+ + + +GE WIV DG VD W+ENLNSVLDDN+ LTL NG+R+ + PN +++FE ++ A+ ATVSR GMV+ S VL IL +L + S N+ + + QL + S L F + +LE MD + +M++ +I + + P ++ + I +++WS +L+ R+++ + + + LP + G + + D+ V +G WV WS +V + + +T + ++VP +D VR + L+ T + + VLL G G+ KT+ + S + + P++++ LNFSSATTP + +T + Y + R G P K I D+IN+P ++++G Q +RQ++E GFY + ++ + +QF+ A P GR + R R + P S+ +I+ + RG+ + + + + L T+ + M P HYI++ R+++R +G+ + + SV L+ +W HE R+ DR D+ W D + ++ + +K + ++R + ++L A +E E D+ +K RL +F Y + + + +V F + H++++ R+ R P G+ LL+GV G+GK +L+R S+I G +FQ+ + Y + EDL+++ R +G +G+ I+FI ++ + + SFLE MN +L++GEV LF +E+ +++ RE + E LY +F ++ NLHVV +P + +++A PAL + C ++WF W +A +V F + D++ C +P + VV + + + V R R+ +TP+ YL I Y + EKRA++ +N GL+K+++ + V + + L K +EL+ NE A+ LK++ + +E K Q +K++ + + +++L+ P + EA+ A+Q I+ DI ++ + PP + ++ + LLL + T+ WQ L ++ +F++ + F D +++ T E ++ Y + P+YN E+ AS+ ++ W A S+ I K V PL+ L A ++NR + + E A+L+ A+ EY +++ T+ D K+ + L+ L+ E+ RW S+ F AQ + GD LL++AF++Y G F+Q R+ L N W L + I F ++L E L + W LP D+L + N II+ + R+PL+IDP Q T++ N+ + ++ TS FR LE +L G PLL++DV E DP+L+ VL + +TG + +GD+++D+ F ++++T+ P+ + P+I +R + ++FTVT L++Q L V+ E+ +++++R+DLL+ + K++ LE +LL L QG+L++++ +I L K+ A +V +K++ ++ + EY P+A S +YF + M+ ++ +YQ SL L +F L + + +N S+R+K I + + Y ARG+ E + + +I ++G EF ++ + + K L + ++ L KL F++I +++ + + K+W + PE V N+Y + LL+I+ PDR +A +K+I +G+ +TE V LD+ E E P++ G DP+ + L + + +++G + A K + G W +L+N HL +++ L + I + + +FRL++T E+ P+ LL+ EPP G+KA L RT IN + + + + + +A+L++ VQER ++ PLG++ YEF ++DF + I +D M L + W +Q ++G YGG++ + +D+RLLN+F F + F+ +F P+ + L ++ LP TP GL +A+ + + ++ IL +Q D G+++ + D L+ LP P + + ++ + PM +E++ ++ VR L D+ G + + R + + IP W++ L W + +R +Q ++ + R W+ G F + ++TA +Q +A+ NK WAL+ + L Sbjct: 782 NKYKFPVQKEEGEKVETLRLYWDKLMFRSTE-VQSELETLQPKFKKELESNMIVLQEECQNFYQDYDKDGPMGVGLAPQDVSDRLIMFQNQFDNLFLKYTTYCDGAKLF-----GITVTQHPQLMKIRTELTLLQKLYGLYNNVIETVNGYYDILWTNINIEKINNELLDFQTRCRKLPQALKEWQAFLDLKRTIDEFSECCPLLELMTSKAMMARHWKRITEVTGHNLDVESENFKLRNIMEADPLKYKEEIEDICISAVKERDIEQKLKEVITEWDNKTFTFAGFKNRGELLLRGDSTSELIASLEDSLMVLGSLMSNRYNTPFKAQIQKWVQYLSNTSDIIEHWMIVQNLWIYLEAVFVG-GDIAKQLPKEAKLFSSIDKSWMKIMTRAHEMPNVVQSCVGDVTMGQLLPHLLEQLDSCQKSLTGYLEKKRLLFPRFFFVSDPALLEILGQASDSHTIQAHLLNVFDNIKSVQFHEKIYDRILAVSSREKETMELDRPIT--AEGNVEVWLNALLKESQRSLHLVIRQAALAIQNEGFE-------LIDFLNSFSAQVGLLGIQMIWTRDSEEALTNAHYDRGIMSKTNQHFLNLLNTLIDMTTKDLGAVERTKYETLITIHVHQRDIFDDLCRLHIDNPSDFEWLKQCRFYFN-EDSD---KMTINITDVSFDYQNEFLGCTERLVITPLTDRCYITLAQALGMCMGGAPAGPAGTGKTETIKDMGRCLGKYVVVFNCSDQMDFRGLGRIFKGLAQSGSWGCFDEFNRIELPVLSVAAQQIAIV-------LTCKKDRHKTFVFTDGDSVDMNPEFGIFLTMNPGYAGRQELPENLKINFRSVSMMVPDRQIIIRVKLASCGFIDNVKLACKFFTLYKLCEEQLSKQVHYDFGLRNILSVLRTLGAAKRANPSDTESTIVKR----------------------VLKDMNLSKLIDEDEELFLSLIEDLFPGIELNKEGYPELEAAIDKKIQETGLINHPP--------WKLKVIQMYETQRVRHGMMALGPSGSGKTTCIQILMKAMTEC-GQPHREMRMNPKAITAPQMFGRLDVATNDWTDGIFSTLWRKTLKAKKGE---HIWIVLDGPVDAIWIENLNSVLDDNRTLTLANGDRIPMAPNCKVVFEPHNIDNASPATVSRNGMVFMSSSVLGWSPILEGWLKQR------------SPNEAEV------------LRQLFSSSFSELYRFSVQ------------SLEFKMDMLEAFVIMQCINMLQ----GLIPLKEQCGELP------REHLERLYIFALMWSAGALLELEDRKKMELWFRGNDVIRRSLPEIPPGREETMFDYYVTAEGHWVHWSTRVEEY-IYPPDVTPKYSSILVPNVDNVRTDFLIDTISKQGKAVLLIGEQGTAKTVIMKSFMSKYDPEIQLGKCLNFSSATTPLMFQRTVESYVDKRM---GTTYGPPAGKKMSILI-DDINMPVVNEWGDQVTNEIVRQLMEQKGFYNLEKPGEFTNIVDVQFLAAMIHPGG-GRNDIPQRLKRQFSIFNCTLPSNASIDKIFGVIGEGHF---CAQRGFIEEVQRTIPQLVLLTRRLWQLTKIKMLPTPAKFHYIFNLRDLSRIWQGMLCTNAEVIN-SVHVLLALWKHECKRVIADRFTMPDDVEWFDQTLAKLVEQQLGEEHKKVVDCGVER--YFVDFLRDPPEATGEEPEESDFDMPKVYEPIESFESLKDRLNMFLCQYNDSIRGNGMDMVFFQDAMIHLIKVSRIIRTPGGNALLVGVGGSGKQSLTRLASFIAGYKIFQITLTRLYNTTNLMEDLKSLYRIAGHQGKGISFIYTDNEIKEESFLEYMNNVLSSGEVSNLFARNEMDEILSDLVPVMKREFPRRPPTNENLYDYFMSRVRHNLHVVLCFSPVGEKFRNRALKFPALISGCTMDWFSRWPKDALVEVSHHFLSAFDID-----------C--------SPQVKSEVVQCMGSFQDCVAEKCVDYFLRYRRSTHVTPKSYLSFIQGYKTIYVEKRAEV------MNTGLQKLKEASESVAALSKELEVKEKELQIANEKADMVLKEVTVKAEASELVKVEVQKVKDKAQAIVDSITADKAIAEEKLEAARPALEEAEAALQTIKPSDIATVRTLSRPPPLIMQTMDCVLLLLRRRVNPVEINAETNFITSSWQESLNLMTSGSFLSELKQFPKDTINEETVELLQP-YFNLPNYNIERARTASSNVAGLLSWTKAMASFFAINKEVLPLKANL-----AVQENRLAVANLDLEKAQAELDAKQAELNVVRAEYEEAMTEKLTLLEDAKRCRRKMQIASNLISGLAGEKERWTEQSKEFAAQTKRLVGDVLLATAFLSYSGPFNQEFRSLLLNEWQCELKQRSIPFGNNLDITELLIDASTVSEWNLQGLPNDELSIHNGIIVTKAARFPLLIDPQTQGKTWIKNKEAKNELQITSLNHKYFRNHLEESLSLGRPLLIEDVGEELDPVLDNVLEKNFIKTGSTYKVKIGDKEVDVMKGFKLYMTTKLPNPAYTPEISARTSIIDFTVTIRGLEDQLLGRVILTEKREMEKERTDLLEDVTYNKRKMKELEDNLLYRLTSTQGSLVDDESLIVVLGNTKQTAEEVNQKLQIAGDTQIQINAAREEYRPVATRGSILYFLITEMSMVNVMYQTSLTQFLGLFDLSLARSSKSSN---TSERIKSIIEYMTFKVYYYAARGLYEEHKFLFTLLLTLKIDMQGK---NVTHKEFLTLIKGGASLDLKTCPQKPAEWILDMSW---LNLVELSKLWQFSEILDQISHHEKLWKSWF-----DKEAPEEEVLPNSYQSLDCFR------RLLLIRCWCPDRTIAQARKYIRDAMGEKYTEGV--ILDVEGTWE-ESNPRTPLICFLSMGSDPTDSIIALGKKLKIETRYVSMGQGQEV-HARKLLQQTMANGGWALLQNCHLGLNFMDELMDTVIETECINDSFRLWITTEVHKNFPITLLQMSIKFTNEPPQGLKAGLKRTYGGINQDLLDVSNTNQWKPMLYCVAFLHSTVQERRKFGPLGWNIPYEFNQADFNATVQFIQNHLDD--MDTKQL----VSWNTVQYMIGEIQYGGRVTDDYDKRLLNTFSKVWFNKNMFERDFNFY------KGYGIPKCSSVDQYLAYIQGLPAYDTPEVFGLHPNADITFQSKQAKDVLDTILSIQPK---DSSSGGGETREAAVSRMADDM--------------LEKLPPDYIPFEVKRLQKMGPLKPMNIFLRQEIDRMQRVIMLVRSTLIDLKLAIDGTIIMSENLRDALDCMYDARIPARWMKSWASSTLGF--WFTELLERNRQF--------QTWLFKGRPNCFWMTGFFNPQGFLTAMKQEIARANKGWALDRMVL 4002
BLAST of Cytoplasmic dynein 1 heavy chain 1 vs. Ensembl Medaka
Match: dnah12 (dynein axonemal heavy chain 12 [Source:NCBI gene;Acc:101164478]) HSP 1 Score: 1164.44 bits (3011), Expect = 0.000e+0 Identity = 906/3262 (27.77%), Postives = 1557/3262 (47.73%), Query Frame = 3 Query: 4314 LKSEAIKERHWRMLMRKLNVSWSLN-ELQLGKVWDIDLVKNEEIIREVLAIAQGEKALEEYLRQITEVWKNYVLELTNYQSKS-KIIKGWDDLFNKVKEHINNVTSMKASPYFKQFEEEATAWEDRLNKINALFDVWIDVQRRWIYLDGIFAGSADIKVLLPVESQRFQSVSTEFLGLMKKVQKSPLVTDVLNIANVQRQLERLAD---LLGKIQKSLGEYLERQRSSFPRFYFVGDEDLLEIIGNSXXXXXXXXXXXXMFAGVHSIILSEDEKVILGMMSKEGEELRFISPVSIIE-HPRINDWLTAMEKEMRVSLAKYLNVAVKEISGWRTESNIDKDKFMVWLDKYQAQIVVLAAQITWSEAVEASLASGVSLESTMTVVHSTLNMLADTVLYEQPPVRRRKLEHLIIEYVHQRDVLRALHNDGVSSNKNFDWMSQMRFYFDPKQTDPLHQLSIHVANAKFHYGFEYLGVCDRLVQTPLTDRCYLTMTQALEARLGGSPFGPAGTGKTESVKSLGNQLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLSAVSQQIQGIQEALRELMVSKKDSINVELLGKQVHVNPDMAIFITMNPGYAGRSNLPDNLKKLFRSLAMTQPDRQLIAQVMLYSQGFRTAEVLAGKVVPFFKLCDEQLSPQSHYDFGLRALKSVLVSAGNVKRDRIKQEKEKIVARGEEINETAIAEQLPEQEILIQSVMETMVPKLIADDIPLLYSLLTDVFPGVEYRQAEMKRLREELRKVSENKFLVYSDEPNTAGYLWVEKVLQLYQITTIHHGLMMVGPSGSGKTMACRVLLQAL----ENIDGIEG--VAHIIDPKSISKDSLYGYMDPNTREWTDGLFTHILRRIIDSVRGESNKRQWIVFDGDVDPEWVENLNSVLDDNKLLTLPNGERLAIPPNVRIMFEVQDLKYATLATVSRCGMVWFSEEVLTTGMILTHFLNELKKVQVMEGEEDFSVNQGDTGADADSKISSSPIIQLQTQVSSILAPFFTEDGLIAKCLDY-STTLEHIMDFTRLRALTSLFSMIKQSIRNMIEYNQSHSDFPLNNEQIENYVAKSLISSVVWSMSGDSKLKVREQLSQYIK--------------NISTVDLP-TVGGIKNIIDFEVNIQGTWVAWSNKVPQIEVETHKITATDVVVPTMDTVRHEALLYTWLAEHRPVLLCGPPGSGKTMTLFSALRCLPDMEV---VGLNFSSAT----TPELMLKTFDQYCEYRKTPNGIVLAPQQLNKWLIFFCDEINLPDMDKYGTQRVISFLRQMVEHHGFYRITDMQWVSFERIQFVGACNPPTDPGRKPLSHRFLRHVPVVYVDYPGETSLKQIYST---FNRAMLRMLPSLRGYADTLTNAMVEFFLKTQERF-THDMQPHYIYSPREMTRWVRGIHEALKPLESLSVEG---LVRIWAHEALRLFQDRLVEEDERHWTDDNINEVALKHFPNI-------------NKEEALKRPILYSNWLSKD-------YSAVTQ-EELRDYVKARLKVFYEEELD-VPLVLFNQVLDHVLRIDRVFRQPQGHLLLIGVSGAGKTTLSRFVSWINGLSVFQVKVHNKYTAEDFDEDLRN-VLRRSGCKGEKITFIMDESNVMDSSFLERMNTLLANGEVPGLFEGDELTTLMTQCKEGAIREGLMID-SQEELYKWFTQQICRNLHVVFTMNPSADGLKDKASTSPALFNRCVLNWFGDWSLEAYFQVGKEFTNRLDLERTDYKVPDTLPCIAEGLLPQNPIYRDVVVNALVFVHQTMHQANVRVQKRGGRTAAITPRHYLDLIAHYMKLSAEKRADLEEQQLHLNNGLKKIEQTVDQVEVMQRSLTKKRQELENMNEAANAKLKQMVQ---------------DQQEAEQKKTTGQALKEELAKQEQFVNEKQKTVKQELDQVEPTVNEAKQAVQNIRKKDIQEIKAMKNPPNAVKMAVESICLL-------------LGEKTTDWQSILKVIIKD-TFVTSILNFNTDDVSDNTRETMKKKYLSNPDYNFEKVNKASNACGPMVKWVLAQISYADILKRVEPLRNELTELSDA-------AEQNRKKSQETEDLIAQLEKSIAKYTEEYATLISQAQTIKSDLASVESKVGRSVALLGSLSSERTRWDSGSETFKAQMATINGDCLLSSAFMAYGGYFDQHMRTSLFNTWCHHLSEADILFRSDLARVEYLSNPDDRLRWQANSLPADDLCVENAIILRRYNRYPLIIDPSGQATTFLLNEYKEKKITKTSFLDDSFRKTLESALRFGTPLLVQDV-ESYDPILNPVLNREVRRTGGRTLITLGDQDIDLSPTFTIFLSTRDPSVEFAPDICSRVTFVNFTVTRSSLQNQCLNAVLKIERPDIDQKRSDLLKAQGEFQLKLRHLEKDLLQSLNEAQGNLLENDKIIARLETLKREAADVAKK-----VEETDVVMQEVESVSTEYVPLAQSCSNIYFTLEAMNQIHFLYQYSLQLMLDIFSSVLINNPELTNVKAASDRLKIITKNLFQVTYNRLARGMLHEDQITFATILARIFLKGSTPIGFLENEFQHFLRSQEATITSSDSNKQDNLGLTLHQDQIDSVKRLKKLKVFAKIEEKVKSTKDIKNWTLTVTPES-NVPELWVDDNNYNDEKLSKIAKGMYNLLIIQAIRPDRLLASTQKFIASVLGDTFTESVRGTLDLASIVEVEVTACVPILLCAVQGYDPSGRVEDLASEQ---GKQLTGIAIGSAEGFSQAEKAINSAAKTGKWVMLKNVHLATSWLVSLEKKIHSLQ---AHPNFRLFLTMEITPKLPVNLLRAGRVLVFEPPPGIKANLLRT-----LSSIN--NQRMSKEPVERSRLYFLLAWLNAIVQERLRYVPLGYSKKYEFGESDFKCALDTIDTWVDGAAMGRTNLPPEKIPWVALQTLLGSCIYGGKIDNAFDQRLLNSFLGYLFTE---KCFDHNFALVSDADDGSNIAFPESTKHTDILQWVHKLPDLQTPSWLGLPNSAEKVLLTNLGQSLIGNILKMQQSLEDDEELVVGQSKTKRTIEVGDGRPAWMRQLYQSTQTWL-QILPKSVTPLQRTIENIKDPMYRCFEREVNSGC-------NLLASVRKDLEDVAEVCKGAKKPTNHHRSMMADLAKGIIPKMWIRYAIPPGLTVIQWIQDFADRIKQLLHISDTAAKSGVIALRSIQVWLGGLFMAEAYITATRQS 13700 L + ++ RHW + + + N L K+ + L E + A E +LE+ ++ +T+VW ++ I DD+ + + I +M SP+ K F+ E WE+RL I D W+ +Q +W+YL+ IF+ S DI +P E + FQ+V + +M K + VL ++ LERL D LL KI K L YLE++ R +F M S EGE + I +S E + + WL +E M S+ ++ + R +++ W+ ++ Q+V+ +QI W+ V +L L+ + + LN + + V E P R L L+ VH RDV++ L + VS +F+W++Q+R+Y+ D + +H+ N Y +EYLG RLV TPLTDRCY T+ A LGG+P GPAGTGKTE+ K L L +VFNC + D+ AMG+ F GL GAW CFDEFNR+E +LS V+QQ+ IQ A+ + K + + E G + +NP+ + ITMNPGYAGRS LPDNLK LFR++AM P+ LIA++ LYS GF A+ L+ K+V ++LC EQLS Q HYD+G+RA+K+VL++AGN+K + E E I +L++S+ + PK ++ DIPL + +D+FPGV A+ K E +E +++ +P ++ +K++Q Y++ + H M+VG S +GKT VL L E G E + ++PKSI+ L+G D + EWTDG+ + R E+ R+W+VFDG +D W+E++N+VLDDNK L L +GE + + + ++FE DL A+ ATVSRCGM++ L ++ ++N L D D++ S I+ L ++ P + L C + TT H + AL LF MI + E ++ D +E I ++ + SS+VWS+ G RE+ + +I+ I + P G+ +E +G W+ W++ + I + +++VPT+DTVR+ L+ +++ P+L GP G+GK++ + L D + +NFS+ T T +++ D K G+ P L K + F D++N+P +++G Q + LRQ ++H G Y + D +S +QF+ A PP GR ++ RFLRH+ ++ ++ + ++ I+S+ F+ P + + AM+E + K + HY ++ R+ +R ++G L+ S+EG L+R++ HE R++ DRLV++++R W +N + HF N+ EE + +L+ ++++ D Y+ V E + VK+ L+ + + + + LV+F +L+H+ RI RV +QP G+ LL+GV G+G+ +++R + + +++FQ ++ Y ++ +DL+ +LR +G KG+K F++ ++ + D +FLE ++++L GEVP LF DE ++ + A ++ S L+ +F + NLHVV +P + + P+L N C ++WF W EA +V F L++ + R V+ H + +Q + Q GR ITP YL+LIA + +L ++KR + + NGL ++ +V M++ L + +LE + N K+ ++++ D++ A K QALK E + LD ++ + DI +KAMKNPP+ VK+ + ++C++ G+K D+ K ++ D F+ + ++ D++ +T++ ++++NPD++ KV AS+A + KW+ A Y + K V P + +L E ++ +Q R + +E ED + L+K+ + TEE A L Q + S K+ R+ L+G LS E+ W ++ + + GD L+S+ +AY G F R + W +I D + + L NP + W LP D ++N +I+R +R PL+IDP GQA ++ N K+ + D + +TLE+ ++FGTPLL+++V E DP L P+L ++ + G + I LG++ I+ S F +++TR + + P++ ++V+ +NF +T L++Q L V+ E P+++++R+ L+ + +L+ +E +L++L ++GN+LE++ I L++ K + ++ KK E+T++ + E Y +A+ S ++F++ + I +YQYSL ++++ IN+ + K RL+ + + Y + R + +D++ F+ +L L +E+ FL + + ++ +N + L D + R +L F +E +K+ +D K + P S ++P W EKL+ + K ++I + +RPD + A T KF+ LG F + DL ++ + +P++ G DP ++ AS++ G + I++G +G A K I +A + G WV L+N HLA SW+ +LEK H +FRL+LT +PK PV +L+ G + E P G++ NLL++ +S N N K+PV +L F L + +A+VQER ++ PLG++ Y F ESD ++ + +V+ +K+P+ A+ L G C YGG++ + +D+RLL + L + E K F + + G A P+S+ + D +Q++ LP Q P GL + + I L+ + L D L G GD LY L Q LP + R +K P+ +E +N+ NL +++ L+++ + KG + ++ +L G +P+ W +++ P + +I DF R+K L + + V WL G F +A++T Q+ Sbjct: 580 LCNPGLRGRHWEKMSQIAGFDLTPNFGTSLRKLLQLKLEPFLEEFETISVAASKEFSLEKAMQTMTQVWDGVSFHHQPHKDTGVSIFTALDDIQMMLDDQIVKTQTMMGSPFVKPFQSEMKQWEERLLHIQESIDEWLKLQAQWLYLEPIFS-SQDIMQQIPEEGRLFQTVDRNWREIMGHCVKD---SKVLQATSLPGLLERLQDSNALLEKIMKGLNAYLEKK-----RLFF-------------------------------------------PMYSSEGERVELIQNISTSEANGAVEKWLLQLEDGMISSVRDIIDRS-------RAYEKTARNQ---WVKEWPGQVVLCTSQIFWTLEVHKALG----LKKYYQQLQNQLNEIVELVRGELPKQTRTTLGALVTIDVHARDVVKDLI-EKVSDETDFEWLAQLRYYW---MND---NVRVHIINCDVKYAYEYLGNSPRLVITPLTDRCYRTLIGAFHLNLGGAPEGPAGTGKTETTKDLAKALAVQCVVFNCSDGLDYLAMGKFFKGLASSGAWACFDEFNRIELEVLSVVAQQVLCIQRAI----MHKLEYFDFE--GTMLKLNPNCFVSITMNPGYAGRSELPDNLKVLFRTVAMMVPNYALIAEISLYSYGFLNAKPLSAKIVMTYRLCSEQLSSQFHYDYGMRAVKAVLLAAGNLKL-KFPNENEDI--------------------LLLRSIKDVNEPKFLSHDIPLFNGITSDLFPGVSLPVADYKLFLE----AAEECCKIHNVQPTK---VFTDKLIQTYEMMIVRH-FMLVGESFAGKTKVLHVLADTLSLMNERGHGEEEKVIFRTLNPKSITMGQLFGQFDLVSHEWTDGVVANTFREF---ALAETPDRKWVVFDGPIDTLWIESMNTVLDDNKKLCLMSGEIIQMSNQMSLIFEANDLSQASPATVSRCGMIYMEPSQLGWKPLVISWINTLP----------------DPLQSPDNR---SLILDL---FHWLIPP--SLQMLRRHCREVVPTTNSHT-----VVALCRLFKMI------LDEPVKTGPD----DESIRTWIMAAFASSLVWSVGGCCDTDSREKFNDFIRQTVSGKNKEHPIPETIERWECPINEKGLVYDYFYEFKEKGRWIHWNDTIENINLGEINTKGQEIIVPTIDTVRYTYLMDLCISQG-PLLFVGPTGTGKSVYVKDKLLNNLDKDCYLPFFINFSAHTSANQTQNIIMSKMD------KRRKGVFGPP--LGKRYVLFVDDLNMPAREQFGAQPPVELLRQFLDH-GHYDLKDTSKISLVDVQFIAAMGPPGG-GRNAVTSRFLRHLNIISINPFSDDTMVHIFSSIVAFSMKKNLFSPEFVIVGNQIVTAMMEVYKKAMANLLPTPAKSHYTFNLRDFSRVIQGCLL----LKKGSLEGKQTLIRLFVHEVYRVYHDRLVDDEDRTWLYQLMNSIVKDHF-NVPFDQVFGQLKQGDKLEEKDMQNLLFGDYMNPDLEGDERLYTEVPSIETFAEVVKSCLEEYNQMHKNRMNLVIF-YLLEHLSRISRVLKQPGGNALLVGVGGSGRQSITRLATSMAHMTLFQPEISKNYGMTEWRDDLKQMLLRNAGVKGQKTVFLITDTQIKDEAFLEDIDSVLNTGEVPNLFAVDEKQEIIETIRPIAQAGKKSVELSPLTLFAFFVARCKENLHVVVAFSPIGKAFRKRLRQFPSLINCCTIDWFQPWPEEALERVANSFLESLEMSENE---------------------RQEVITICKTFHTSANQLS-DFQAELGRYNYITPTSYLELIATFQQLISQKRETIMNAKQRYINGLDQLAFAESEVAKMKKELVDLQPKLEQA-KIDNTKMMEVIEVESIEVEAKSRVVHVDEEAAAMKANEAQALKSECENDLAEALPALEAALTALDTLK-------------QPSDISIVKAMKNPPSGVKLVMAAVCVMKNVKPDRIPDPAGTGKKILDYWGPSKKLLGDMNFLRDLKEYDKDNIPVPVMQTIRNEFMTNPDFDPSKVANASSAAEGLCKWITAMEVYDKVAKVVAPKKAKLAEAQESLAATKAVLDQKRAELKEVEDRLTALQKTFEEKTEEKARLEMQVE-------SCARKLERAEKLIGGLSGEKI-WSKAADDLQNTYDNLTGDVLISAGVIAYLGPFTSGFRQNCTKLWTTLCQSKNIPSSDDFSLSKTLGNPIEIRAWNIAGLPNDSFSIDNGVIVRN-SRRPLMIDPQGQANKWVKNLEKDNNLNVIKLTDGDYMRTLENCIQFGTPLLLENVGEELDPSLEPLLLKQTFKQGVES-IKLGERVIEYSADFRFYVTTRLKNPHYLPEVATKVSLLNFMITPEGLEDQLLGIVVAKE-PELEEERTALILQSANNKRQLKEIEDSILETLQSSKGNILEDESAIQILDSAKIMSNEITKKQQIQIAEKTELKIAESRE---GYREVAKHSSILFFSIADLTNIDPMYQYSLIWFVNLY----INSIQDIKSKVLKQRLEYLKDHFTYNLYCNVCRSLFEKDKLLFSFLLCCNLLARKE----IEHSDLMFLLTGGIGLQNTVANPDPSW---LQDKSWDEICRASELPGFQGLEAFIKNPEDFKLIYDSREPCSIDLPAPWC-------EKLTDLQK----MIIFRCLRPDMVPAVT-KFVTRNLGKKFVQP--PAFDLTKSF-LDSNSTIPLVFVLSPGADPMALLK-FASDKKMDGSRFQSISLGQGQG-PIAAKMIFTAMQNGSWVCLQNCHLAVSWMSNLEKICEDFSLTTCHQDFRLWLTSYPSPKFPVGILQNGVKMTNEQPTGLRLNLLQSYLTDPVSDPNFFNGCPDKKPV-WEKLLFGLCFFHALVQERKKFGPLGWNIPYGFNESDLHISMRQLQQFVNEY---------DKVPFEAITYLTGECNYGGRVTDDWDRRLLMTTLADFYCEDIIKTFRYPL-----SPSGKYFAPPKSS-YEDYIQFIENLPISQQPEVFGLHENVD-----------ISKDLQQTKLLFDSLLLTQGGGAMGGVSSGGDN------TLYDIANNILTQQLPPT---FDREAVLLKYPVL--YEESMNTVLVQEMERYNLCSTICVSLQNLLKALKGLVVMDSELEAVAGNLIVGKVPEKWAKFSYPSLKPLGSYITDFLARLK-FLQVWYENGQPKVF-------WLSGFFFTQAFLTGVMQN 3550
BLAST of Cytoplasmic dynein 1 heavy chain 1 vs. Ensembl Medaka
Match: si:dkeyp-86b9.1 (dynein axonemal heavy chain 10 [Source:NCBI gene;Acc:101170214]) HSP 1 Score: 1109.36 bits (2868), Expect = 0.000e+0 Identity = 902/3317 (27.19%), Postives = 1584/3317 (47.75%), Query Frame = 3 Query: 3930 EAVNIIQILEGKFNRLKEERENVQKAKEALELTEIGVKP--ISEEKVTNALSELHDLKNVWNELKSIWEKIRDMKETPWLSVQPRKLRQDIENLTAQLKELPNSFKQYASFEHVRTLLKMYMKVNASIVELKSEAIKERHWRMLMRKLNVSWSLN--ELQLGKVWDIDLVKNEEIIREVLAIAQGEKALEEYLRQITEVWK----NYVLELTNYQSKSKIIKGWDDLFNKVKEHINNVTSMKASPYFKQFEEEATAWEDRLNKINALFDVWIDVQRRWIYLDGIFAGSADIKVLLPVESQRFQSVSTEFLGLMKKVQKSPLVTDVLNIANVQRQLERLADLLGKIQKSLGEYLERQRSSFPRFYFVGDEDLLEIIGNSXXXXXXXXXXXXMFAGVHSIILSED---EKVILGMMSKEGEELRFISPVSIIEHPRINDWLTAMEKEMRVSLAKYLNVAVKEISGWRTESNIDKD---KFMVWLDKYQAQIVVLAAQITWSEAVEASL-----ASGVSLESTMTVVHSTLNMLADTVLYEQPPVRRRKLEHLIIEYVHQRDVLRALHNDGVSSNKNFDWMSQMRFYFDPKQTDPLHQLSIHVANAKFHYGFEYLGVCDRLVQTPLTDRCYLTMTQALEARLGGSPFGPAGTGKTESVKSLGNQLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLSAVSQQIQGIQEALRELMVSKKDSINVELLGKQVHVNPDMAIFITMNPGYAGRSNLPDNLKKLFRSLAMTQPDRQLIAQVMLYSQGFRTAEVLAGKVVPFFKLCDEQLSPQSHYDFGLRALKSVLVSAGNVKRDRIKQEKEKIVARGEEINETAIAEQLPEQEILIQSVMETMVPKLIADDIPLLYSLLTDVFPGVEYRQAEMKRLREELRKV-SENKFLVYSDEPNTAGYLWVEKVLQLYQITTIHHGLMMVGPSGSGKTMACRVLLQALENIDGIEGVAHIIDPKSISKDSLYGYMDPNTREWTDGLFTHILRRIIDSVRGESNKRQWIVFDGDVDPEWVENLNSVLDDNKLLTLPNGERLAIPPNVRIMFEVQDLKYATLATVSRCGMVWFSEEVLTTGMILTHFLNELKKVQVMEGEEDFSVNQGDTGADADSKISSSPIIQ--LQTQVSSILAPFFTEDGLIAKCLDYSTTLEHIMDFTRLRALTSLFSMIKQSIRNMIEYNQSHSDFPLNNEQIENYVAKSLISSVVWSMSGDSKLKVREQLSQYIKNISTVDLPTVGG-------IKNIIDFEVN-IQGTWVAWSNKVPQIEVETHKITATDVVVPTMDTVRHEALLYTWLAEHRPVLLCGPPGSGKTMTLFSALRCLPDMEVVGL--NFSSATTPELMLKTFDQYCEYRKTPNGIVLAPQQLNKWLIFFCDEINLPDMDKYGTQRVISFLRQMVEHHGFYRITDMQWVSFERIQFVG--ACNPPTDPGRKPLSHRFLRHVPVVYVDYPGETSLKQIYSTFNRAMLRMLPSLRGYADTLTNAMVEFFLKTQERFTHDMQP-----HYIYSPREMTRWVRGIHEALKPLESLSVEGLVRIWAHEALRLFQDRLVEEDERHWTDDNINEVALKHFPNINKEEALKRPILYSNWLSKDYSAVTQEELRDYVKARLKVFYEE--ELDVP---LVLFNQVLDHVLRIDRVFRQPQGHLLLIGVSGAGKTTLSRFVSWINGLSVFQVKVHNKYTAEDFDEDLRNVLRRSGCKGEKITFIMDESNVMDSSFLERMNTLLANGEVPGLFEGDELTTLMTQCKEGAIREGLMIDSQEELYKWFTQQICRNLHVVFTMNPSADGLKDKASTSPALFNRCVLNWFGDWSLEAYFQVGKEFTNRLDLERTDYKVPDTLPCIAEGLLPQNP-IYRDVVVNALVFVHQTMHQANVRVQKRGGRTAAITPRHYLDLIAHYMKLSAEKRADLEEQQLHLNNGLKKIEQTVDQVEVMQRSLTKKRQELENMNEAANAKLKQMVQDQQEAEQKKT-TGQALKEELAKQEQFVNEKQKTVKQELDQVEPTVNEAKQAVQNIRKKDIQEIKAMKNPPNAVKMAVESICLLLGEKTTDWQSILKVIIKDTFVTSILNFNTDDVSDNTRETMKKKYLSNPDYNFEKVNKASNACGPMVKWVLAQISYADILKRVEPLRNELTELSDAAEQNRKKSQETEDLIAQLEKSIAKYTEEY--ATLISQAQTIKSDLASVESKVGRSVALLGSLSSERTRWDSGSETFKAQMATINGDCLLSSAFMAYGGYFDQHMRTSL-FNTWCHHLSEADILFRSDLARVEYLSNPDDRLRWQANSLPADDLCVENAIILRRYNRYPLIIDPSGQATTFLLNEYKEKKITKTSFLDD-SFRKTLESALRFGTPLLVQDV-ESYDPILNPVLNREVRRTGGRTLITLGDQDIDLSPTFTIFLSTRDPSVEFAPDICSRVTFVNFTVTRSSLQNQCLNAVLKIERPDIDQKRSDLLKAQGEFQLKLRHLEKDLLQSLNEAQGNLLENDKIIARLETLKREAADVAKKVEETDVVMQEVESVSTEYVPLAQSCSNIYFTLEAMNQIHFLYQYSLQLMLDIFSSVLINNPELTNVKAASDRLKIITKNLFQVTYNRLARGMLHEDQITFA-TILARIFLKGSTPIGFLENEFQHFLRSQEATITSSDSNKQDNLGLTLHQDQIDSVKRLKKL--KVFAKIEEKV-KSTKDIKNWTLTVTPESNVPELWVDDNNYNDEKLSKIAKGMYNLLIIQAIRPDRLLASTQKFIASVLGDTFTESVRGTLDLASIVEVEVTACVPILLCAVQGYDPSGRVEDLASEQGKQLTGIAIGSAEGFSQAEKAINSAAKTGKWVMLKNVHLATSWLVSLEKKIHSL-QAHPNFRLFLTMEITPKLPVNLLRAGRVLVFEPPPGIKANLLRTLSSINNQRMS--KEPVERSRLYFLLAWLNAIVQERLRYVPLGYSKKYEFGESDFKCALDTIDTWVDGAAMGRTNLPPEKIPWVALQTLLGSCIYGGKIDNAFDQRLLNSFLGYLFTEKCFD--HNFALVSDADDGSNIAFPESTKHTDILQWVHKLPDLQTPSWLGLPNSAEKVLLTNLGQSLIGNILKMQQSLEDDEELVVGQSKTKRTIEVGDGRPAWMRQLYQSTQTWLQILPKSVTPLQRTIENIKDPMYRCFEREVNSGCNLLASVRKDLEDVAEVCKGAKKPTNHHRSMMADLAKGIIPKMWIRYAIPPGLTVIQWIQDFADRIKQLLHISDTAAKSGVIALRSIQVWLGGLFMAEAYITATRQS 13700 E +NII E + +++ ++E++ K + L+L ++ P IS +K + LS+++++ E K+ W +T W++ + L+ I+ L +L + + + LK + + +++LK+ A+++ HW LM + S+ +N L ++ ++L K I E++ A E ++E WK N +L Q + ++ D++ + + + M S + F + WE L + ++W+ VQ +W+ L+ IF G DI LP E+++ + ++ +F +MK + P + + L L + L +IQK+L +L+ +R+ FPRF+ + D++LL ++G S D +Q+H KM+ + S+ L D + V+ M+S EGE + F PV + R+ DW+ A+ +EM+ RT I K+ ++ W+ YQ +V+ A ++ W+ VE ++ +L+ +H ++ L + R K+ ++++ VH RD++ + +F+W SQ+RFY+ K+ D L + N YG+EY+G+ RL TPLT R YLT+TQAL LGG+ GPAG GKTE+VK L LG F +V +C E D +G+I GL + G WGCFDEFNR+ +LS VS QIQ I+ AL S E G+Q+ ++ M I+ITMNP Y R LP+++K FR + + PD Q I ++ML+SQGF A+ LA K+ +K QLS Q HYDFGL + KSVL AG +KRD + +L E +L++++ + +PKL+++D+P+ L++D+FPG++ + RE + ++ ++ + + D+ V+KV+Q+Y+I M+VG + GK++ L QA G+ + ++PK+ S D LYG DP TR+WTDG+F+ + R I S K ++I+FDGDVD +W+EN+NSVLDDNKLLTL NG+R+ + + ++FEV DL++A+ ATVSRC +V+ + +S +P Q ++ +++ + + + C+D + E I+ T + ++ L M+ ++E S + E +E Y ++L S+ ++ +LK ++L + + +STVD + + DF + Q WV WS+ VP+ + + D ++PT+DT R +L + RPVLL G G+ KT + + L+ + L NFSS TT + + + E R P K L+FF D+IN+P +D +GTQ+ ++ LR +++ G Y Q +SF+ I+ +G A T GR + RFL V + P SL IY++ + R + + + E LK D+ P HY +S RE++R G+ L+VE VR+W +E LR F DRL +E ++ +I ++ ++F + E L PIL+ DY A R+ + R+ YE+ + DV LF ++H+ R+ R+ R +GH LLIG G+ L++ ++ VF++ + Y +F DL+ + + G + + F+ ++++++ FLE++N +L + VP LF DE +++ Q A++EG S+E ++++F ++ NLH+V ++ + D LK + P L + V++W+ WS +A V + C+ E P P + V++ + VH ++ + ++ + R T + +LD I+ Y L LEE+ H V Q + ++ SL + R+ E ++E N KL DQ+ KKT T A EE+ K + T++ AK PP V++ E I +L G+K +W + K++ + F+ S++ + D +S++ T+ K+L N + E++ S A ++K+V + +SY DI K V+P ++++ L Q++ + + ++ + ++K + E+Y A L + Q ++ L +E ++ + L+ L+SER W E K Q + GDCL+++AF++Y G F+ R ++ ++ W + + I +L+N + + W + LP D+ V+N I+ + +R+PL IDP QA ++ N+ K+ + + S L+D F K LE ++++G P L+QDV E DPI+ VL R V + GRT+I LGD++++ P F +FL T + +++P + + +N++ R L++Q L+ Q+ L++ E + L+ L LL L + GN+L+N ++I LE K EA++ KK+ E ++ Y P+A+ + ++F L M ++ +YQYSL L +F L + N++ RL+ I L TYN + + + ++ F+ + +I T G + E +++ S D K + + +L +L + F+ + + +++ + K+W PE L Y+ E LS K LL+++ +R DRL + ++ +G+ + ++ +I E TA PI+ G DP+ + A + G + T IA+G + K + A G W++L+N HL WL LEK + + + NFR+++T P+ +L+ + +V EPP IK N+ T S I+ Q +S + P S L ++LA+ +A+VQER +Y G+S F +SDF +L+ + T++ + IPW +LQ L+G +YGG+ ++FD+R+L ++ F + F +F + D G I P KH + + K+P + TP GLP++ E T + + ++ +Q E VG+ G G + + Q Q L L + + + P +E+ L+ +++ + ++ G + + ++P MW R A ++ W+ R +Q S+ + G + +WL GL + E+Y+ A Q+ Sbjct: 1047 EKLNIIGKFEKELSKIMAKQEHLTKTAKLLDL-QLAEYPEIISIQKYLSGLSQIYNIYKAHKEAKTKW------SQTLWVNFDIKLLQDGIDGFIESLMQLSKDVQTLPVAFFLDSHLKEFRVSLSLLLDLKNTALRD-HWNKLMERTGKSFDMNLQRFTLETLFSLELHKYANDIDEIVTSALKELSIEM-------TWKRTKFNMQPQLKVNQERVFLLGAVDNILVNLDNDVMKLQCMAGSRFGGPFLDAIQQWEKNLTLFSETIEIWLQVQHKWMNLENIFCGE-DICSQLPEEAKKLKKITKKFTEIMKSTENEPNIKKCCTVPGRLSSLWVLRNDLERIQKNLANHLDSKRNEFPRFFLISDDELLNVLG-SVDPACIQEHVIKMYDNIESLRLGVDSSGQTVVGAMVSNEGEVMEFRKPVPL--EARVEDWIMAVLQEMK-----------------RTSRLITKEAVYHYVDWIRSYQCMMVLAANRVWWTWEVENAIKNVNKGDKYALKKYAEQIHRQIDELVTCLGRPTKESDRLKISNVLVTDVHARDIVDNFVGRSIKEVHDFEWESQLRFYW-VKEHDSLF---VRQCNTSLSYGYEYMGLNGRLAITPLTSRIYLTLTQALSMYLGGALAGPAGAGKTETVKDLAKALGLFCVVTHCTEDMDTITLGKIISGLAKCGFWGCFDEFNRIGASVLSVVSSQIQAIRNAL----TSHFKMFQFE--GQQISLDDHMGIYITMNPSYERRPELPESVKVFFRPVVVVTPDVQQICEIMLFSQGFLQAKELAKKMTVLYKTAGIQLSKQPHYDFGLHSQKSVLKMAGKMKRDSL---------------------ELSEDVVLMRALRDINLPKLVSEDVPVFLGLISDIFPGLDSSRVGFPSFRETVEEILQKSNYTILPDQ--------VDKVVQIYEIMLTQQATMIVGQTCGGKSVVINTLCQA--QTLGLCTKLYPLNPKATSVDELYGSFDPETRDWTDGIFSKLFREINQST---DKKERYILFDGDVDSQWLENMNSVLDDNKLLTLANGDRIRLQSHCALLFEVGDLQHASPATVSRCAVVFIDPK----------------------------------------HLSYTPYWQRWMKNRLNRLFEKY------VPSCIDVTLNSETIVPRTDVNMVSQLCLMLDV----LLESKNSSA------EVLECYFLEALYCSLGATLVESGRLKF-DKLVKSLSCLSTVDDEKAAAGPGEIPYLPTLYDFHFDETQEKWVPWSSLVPEY-IHNPAMKFAD-ILPTVDTTRTHWILEQMVKIKRPVLLVGECGTSKTAIIQNLLKNTSTDSSISLTINFSSKTTSLDLQRNLEANIEKRTKD---TYGPPIGKKLLVFF-DDINMPKVDDFGTQQPVALLRLLLDQGGLY--DRKQKLSFKTIKDLGYIAAMRKTGGGRNEVDPRFLSLFSVFNIPPPATESLHLIYASIIKGHTR---PFKAAIQEVCQTITECTLKLFTTIITDLPPTPSKFHYTFSQRELSRIYCGLTLTKPDFSCLTVEQFVRVWRNECLRNFHDRLTDETDKALVHGHIKKLVEEYF-ETDSEAVLADPILFG-----DYRAA-----REECEQRV---YEDIGDYDVSKAIFQLFEDAVEHLTRVHRILRSDRGHALLIGADGSWTQALTKLAAFTADCEVFEIILRRGYNELNFRNDLKTLYLKLGIENRRTVFLFTDAHIVEEGFLEQINNMLISM-VPTLFADDEKESIIKQINSEALQEGAG-SSKESVWQYFLRKSANNLHIVLCLSATGDALKTRCRNFP-LMSNTVIDWYLPWSAQALHAVAQ--------------------CVLEN--PTIPKAHFGAVIDHICMVHASLCDFSKQLLLKHQRCNYATSKSFLDFISSYSTL-------LEEKNEH-----------VLQCKCLEGSLNRLREAREQIDE-LNLKLA----DQKVVLAKKTATCTAFLEEIDKNQ-------------------TISFAK-------------------PPKQVQVVCECILVLRGKKELNWLTAKKMMSEAGFLHSLMQMDCDSISNSHISTI--KFLKNLQTSVEEMQSISKAGSGILKFVESFMSYWDIAKEVQPKKDQVKRLEKEFLQSKAELECIKNDLNNMQKEASSLKEKYEDANLEKELQLDEAKL--MERRLTAADKLVLGLTSER-EWTKDLEELKQQHECLLGDCLIAAAFLSYAGAFNWDFRNNMVYDKWTQDVKQKGIPLSQPFKIENFLTNQLE-ISWGSEGLPPDEQSVQNGILTTKGSRFPLCIDPQQQALNWIKNKEKDNNLKQVSSLNDPDFLKQLELSIKYGYPFLLQDVNEDIDPIIINVLERNVVVSEGRTVIVLGDKEVNYDPNFKLFLHTTLANPQYSPSVFEKALVINYSTLR-GLEDQLLSVTTGFLEKVFQQQHLLLVEEISENKTLLKSLGDSLLMELGTSTGNMLDNTELIQTLEKTKTEASETIKKLSVAQSKTVEFANLREGYRPVAKRGAVLFFALSDMALVNRMYQYSLTSYLSLFELSLQESLAHPNLQ---QRLENIINTL---TYN-VHNYLFGKHKLLFSMNMTVKI---EQTEGGVPQKELDFLIKN-----LSGDGTKVQKPHEWIPDQAWQDITKLAELFPEQFSSLPSDIEQNSTNWKSWWDLRAPEQAPFPL-----QYS-ESLSAFQK----LLLLRCLRADRLHRAMADYVTVTMGNCVHPPL---INFTTIYE-RSTAFSPIVFIMSSGSDPTTDLIKFAEKSGTKFTLIAVGQGQE-QVVLKLLEKAVSIGSWLILQNCHLLVKWLKDLEKALEKITNPNINFRMWITTNAIDDFPIGILQKSQKVVAEPPEDIKLNMKATYSKISQQTLSSCQHPAFCS-LVYVLAFFHAVVQERSKYGKTGWSVPCNFNDSDFSASLEVLSTYLTKCHEQGDSF----IPWESLQYLIGEVVYGGRAIDSFDRRILKVYMDEYFGDFLFSPFQHFHFFRNKDVGYKIP-PPGRKH--VYTEIEKMPLITTPEVAGLPSTVEIGYYTQAVEEMWTHLRVLQ------PETQVGR---------GIGGDEHISHIAQDIQKQLPEL-FDINLVGEELGTDLSPTSVVLLQELRRFNKLVLCMQQSVVELLRALTGEVGMSKESDDLAHAFCNDLVPAMWKRLAPETLKSLDDWMSHLRRRYEQY---SNWQVREGEPKV----MWLSGLHVPESYLAAVVQA 4047
BLAST of Cytoplasmic dynein 1 heavy chain 1 vs. Ensembl Medaka
Match: dnah5 (dynein axonemal heavy chain 5 [Source:NCBI gene;Acc:101171908]) HSP 1 Score: 1082.78 bits (2799), Expect = 0.000e+0 Identity = 795/2866 (27.74%), Postives = 1385/2866 (48.33%), Query Frame = 3 Query: 5733 TPLTDRCYLTMTQALEARLGGSPFGPAGTGKTESVKSLGNQLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLSAVSQQIQGIQEALRELMVSKKDSINVELL--GKQVHVNPDMAIFITMNPGYAGRSNLPDNLKKLFRSLAMTQPDRQLIAQVMLYSQGFRTAEVLAGKVVPFFKLCDEQLSPQSHYDFGLRALKSVLVSAGNVKRDRIKQEKEKIVARGEEINETAIAEQLPEQEILIQSVMETM-VPKLIADDIPLLYSLLTDVFPGVEYRQAEMKRLREEL-RKVSENKFLVYSDEPNTAGYLWVEKVLQLYQITTIHHGLMMVGPSGSGKTMACRVLLQALENIDGIEGVAHIIDPKSISKDSLYGYMDPNTREWTDGLFTHILRRIIDSVRGESNKRQWIVFDGDVDPEWVENLNSVLDDNKLLTLPNGERLAIPPNVRIMFEVQDLKYATLATVSRCGMVWFSEEVLTTGMILTHFLNELKKVQVMEGEEDFSVNQGDTGADADSKISSSPIIQLQTQVSSILAPFFTEDGLIAKCLDYSTTLEHIMD----FTRLRALTSLFSMIKQSIRNMIEYNQSHSDFPLNNEQIENYVAKSLISSVVWSMSGDSKLKVREQLSQYIKNISTV--DLPTV--GGIKNIIDFEVNIQGTWVAWSNKVPQIEVETHKITA--TDVVVPTMDTVRHEALLYTWLAEHRPVLLCGPPGSGKTMTLFSAL-RCLPDMEV-VGLNFSSATTPELMLKTFDQYCEYRKTPNGIVLAPQQLNKWLIFFCDEINLPDMDKYGTQRVISFLRQMVEHHGFYRITD-MQWVSFERIQFVGACNPPTDPGRKPLSHRFLRHVPVVYVDYPGETSLKQIYSTFNRAMLRMLPSLRGYADTLTNAMVEFFLKTQERFTH---DMQP-----HYIYSPREMTRWVRGIHEALKPLESLSVEGLVRIWAHEALRLFQDRLVEEDERHWTDDNINEVALKHFPNINK---EEALKRPILYSNWLSKDYSAVTQE-ELRDY--------------VKARLKVF---YEEEL---DVPLVLFNQVLDHVLRIDRVFRQPQGHLLLIGVSGAGKTTLSRFVSWINGLSVFQVKVHNKYTAEDFDEDLRNVLRRSGCKGEKITFIMDESNVMDSSFLERMNTLLANGEVPGLFEGDELTTLMTQCKEGAIRE-GLMIDSQEELYKWFTQQICRNLHVVFTMNPSADGLKDKASTSPALFNRCVLNWFGDWSLEAYFQVGKEFTNRLDLERTDYKVPDTLPCIAEGLLPQNPIYRDVVVNALVFVHQTMHQANVRVQKRGGRTAAITPRHYLDLIAHYMKLSAEKRADLEEQQLHLNNGLKKIEQTVDQVEVMQRSLTKKRQELENMNEAANAKLKQMVQDQQEAEQKKTTGQALKEELAKQEQFVNEKQKTVKQELDQVEPTVNEAKQAVQNIRKKDIQEIKAMKNPPNAVKMAVESICLLLGEK-------------TTDWQSILKVIIKDTFVTSILNFNTDDVSDNTRETMKKKYLSNPDYNFEKVNKASNACGPMVKWVLAQISYADILKRVEPLRNELTELSDAAEQNR--KKSQETEDLIAQLEKSIAKYT---EEYATLISQAQTIKSDLASVESKVGRSVALLGSLSSERTRWDSGSETFKAQMATINGDCLLSSAFMAYGGYFDQHMRTSLFNTWCHHLSEADILFRSDLARVEYLSNPDDRLRWQANSLPADDLCVENAIILRRYNRYPLIIDPSGQATTFLLNEYKEKKITKTSFLDDSFRKTLESALRFGTPLLVQDV-ESYDPILNPVLNREVRRTGGRTLITLGDQDIDLSPTFTIFLSTRDPSVEFAPDICSRVTFVNFTVTRSSLQNQCLNAVLKIERPDIDQKRSDLLKAQGEFQLKLRHLEKDLLQSLNEAQGNLLENDKIIARLETLKREAADVAKKVEETDVVMQEVESVSTEYVPLAQSCSNIYFTLEAMNQIHFLYQYSLQLMLDIFSSVLINNPELTNVKAASDRLKIITKNLFQVTYNRLARGMLHED-QITFATILARIFLKGSTPIGFLENEFQHFLRSQEATITSSDSNKQDNLGLTLHQDQIDSVKRLKKLKVFAKIEEKVKSTKDI-KNWTLTVTPESNVPELWVDDNNYNDEKLSKIAKGMYNLLIIQAIRPDRLLASTQKFIASVLGDTFTESVRGTLDLASIVEVEVTACVPILLCAVQGYDPSGRVEDLASEQGKQLTGIAIGSAEGFSQAEKAINSAAKTGKWVMLKNVHLATSWLVSL-EKKIHSLQAHPNFRLFLTMEITPKLPVNLLRAGRVLVFEPPPGIKANLLRTLSSINNQRMSKEPVERSR-LYFLLAWLNAIVQERLRYVPLGYSKKYEFGESDFKCALDTIDTWVDGAAMGRTNLPPEKIPWVALQTLLGSCIYGGKIDNAFDQRLLNSFLGYLFTEKCFDHNFALVSDADDGSNIAFPESTKHTDILQWVHKLPDLQTPSWLGLPNSAEKVLLTNLGQSLIGNILKMQQSLEDDEELVVGQSKTKRTIEVGDGRPAWMRQLYQSTQTWLQILPKSVTPLQ-RTIENIK--DPMYRCFEREVNSGCNLLASVRKDLEDVAEVCKGAKKPTNHHRSMMADLAKGIIPKMWIRYAIPPGLTVIQWIQDFADRIKQLLHISDTAAKSGVIALRSIQVWLGGLFMAEAYITATRQSVAQNNK-WALEELFLDVELGEGKVD------SNTCVITGLRLMGSEIVDPRTLKLSTLIYKDI-DICRLKWIRVEKSQQLEGSSAKDK--------VCLPIYLNAARSTV--LFTLYFSTTDSSYDFYKRGVAI 14048 T L CY+T+ QAL +GG+P GPAGTGKTE++K +G LG++V+VFNC + DF+ +GRIF GL Q G+WGCFDEFNR+E +LS +QQI + + KKD + G V +NP+ IF+TMNPGYAGR LP+NLK FRS++M PDRQ+I +V L S GF LA K +KLC+EQLS Q HYDFGLR + SVL + G KR + IV R V++ M + KLI +D L SL+ D+FPG+E + L + +K+ E + + W KV+Q+Y+ + HG+M +GPSGSGKT ++L++A+ G ++PK+I+ ++G +D T +WTDG+F+ + R+ + + +GE WIV DG VD W+ENLNSVLDDN+ LTL NG+R+ + PN +++FE ++ A+ ATVSR GMV+ S VL IL +L + S N+ + + QL + S L F + +LE MD F ++ + L +I +R ++ NQ ++ + I +++WS +L+ R+++ + + + LP + G + + D+ V +G WV WS +V + + +T + ++VP +D VR + L+ T + + VLL G G+ KT+ + S + + P++++ LNFSSATTP + +T + Y + R G P K I D+IN+P ++++G Q +RQ++E GFY + ++ + +QF+ A P GR + R R + P S+ +I+ + RG+ + + + + L T+ + M P HYI++ R+++R +G+ ++ + L+ +W HE R+ DR D+ W D + ++ + +K + ++R + ++L A +E E D+ +K RL +F Y + + + +V F + H++++ R+ R P G+ LL+GV G+GK +L+R S+I G +FQ+ + E L+++ R +G +G+ I+FI ++ + + SFLE MN +L++GEV LF +E+ +++ RE + E LY +F ++ NLHVV +P + +++A PAL + C ++WF W +A +V F + D++ C +P + VV + + + V R R+ +TP+ YL I Y + EKRA+++ +N GL+K+++ + V + + L K +EL+ NE A+ LK++ + +E K Q +K++ + + +++L+ P + EA+ A+Q I+ DI ++ + PP + ++ + LLL + T+ WQ L ++ +F++ + F D +++ T E ++ Y + P+YN E+ AS+ ++ W A S+ I K V PL+ L A ++NR + + E A+L+ A+ EY +++ T+ D K+ + L+ L+ E+ RW S+ F AQ + GD LL++AF++Y G F+Q R+ L N W L + I F ++L E L + W LP D+L + N II+ + R+PL+IDP Q T++ N+ + ++ TS FR LE +L G PLL++DV E DP+L+ VL + +TG + +GD+++D+ F ++++T+ P+ + P+I +R + ++FTVT L++Q L V+ E+ +++++R+DLL+ + K++ LE +LL L QG+L++++ +I L K+ A +V +K++ ++ + EY P+A S +YF + M+ ++ +YQ SL L +F L + + +N S+R+K I + + Y ARG+ E + + +I ++G EF ++ + + K L ++ V+ L KL F++I ++V + + K+W + PE V N+Y + LL+I+ PDR +A +K+I +G+ +TE V LD+ E E P++ G DP+ + L + + +++G + A K + G W +L+N HL +++ L + I + + +FRL++T E+ P+ LL+ EPP G+KA L RT IN + + + + + +A+L++ VQER ++ PLG++ YEF ++DF + I +D M L + W +Q ++G YGG++ + +D+RLLN+F F + F+ +F P+ + L ++ LP TP GL +A+ + + ++ IL +Q D G+++ + D L+ LP P + + ++ + PM +E++ ++ VR L D+ G + + R + + IP W++ + T+ W + +R +Q ++ + R W+ G F + ++TA +Q +A+ NK WAL+ + L E+ + D + + GL L G+ D +L+ K + ++ + W+ E + GSS K K PIY R+ + + ++ TT + RGVA+ Sbjct: 13 TYLMTWCYITLAQALGMCMGGAPAGPAGTGKTETIKDMGRCLGKYVVVFNCSDQMDFRGLGRIFKGLAQSGSWGCFDEFNRIELPVLSVAAQQIAIV-------LTCKKDRHKTFVFTDGDSVDMNPEFGIFLTMNPGYAGRQELPENLKINFRSVSMMVPDRQIIIRVKLASCGFIDNVKLACKFFTLYKLCEEQLSKQVHYDFGLRNILSVLRTLGAAKRANPSDTESTIVKR----------------------VLKDMNLSKLIDEDEELFLSLIEDLFPGIELNKEGYPELEAAIDKKIQETGLINHPP--------WKLKVIQMYETQRVRHGMMALGPSGSGKTTCIQILMKAMTEC-GQPHREMRMNPKAITAPQMFGRLDVATNDWTDGIFSTLWRKTLKAKKGE---HIWIVLDGPVDAIWIENLNSVLDDNRTLTLANGDRIPMAPNCKVVFEPHNIDNASPATVSRNGMVFMSSSVLGWSPILEGWLKQR------------SPNEAEV------------LRQLFSSSFSELYRFSVQ------------SLEFKMDMLEAFVIMQCINMLQGLIPLKVR--LKLNQ--------------HLERLYIFALMWSAGALLELEDRKKMELWFRGNDVIRRSLPEIPPGREETMFDYYVTAEGHWVHWSTRVEEY-IYPPDVTPKYSSILVPNVDNVRTDFLIDTISKQGKAVLLIGEQGTAKTVIMKSFMSKYDPEIQLGKCLNFSSATTPLMFQRTVESYVDKRM---GTTYGPPAGKKMSILI-DDINMPVVNEWGDQVTNEIVRQLMEQKGFYNLEKPGEFTNIVDVQFLAAMIHPGG-GRNDIPQRLKRQFSIFNCTLPSNASIDKIFGVIGEGHF---CAQRGFIEEVQRTIPQLVLLTRRLWQLTKIKMLPTPAKFHYIFNLRDLSRIWQGMLCTNHSSRNIIFQVLLALWKHECKRVIADRFTMPDDVEWFDQTLAKLVEQQLGEEHKKVVDCGVER--YFVDFLRDPPEATGEEPEESDFDMPKVYEPIESFESLKDRLNMFLCQYNDSIRGNGMDMVFFQDAMIHLIKVSRIIRTPGGNALLVGVGGSGKQSLTRLASFIAGYKIFQITLTRSGLLEGLIAYLKSLYRIAGHQGKGISFIYTDNEIKEESFLEYMNNVLSSGEVSNLFARNEMDEILSDLVPVMKREFPRRPPTNENLYDYFMSRVRHNLHVVLCFSPVGEKFRNRALKFPALISGCTMDWFSRWPKDALVEVSHHFLSAFDID-----------C--------SPQVKSEVVQCMGSFQDCVAEKCVDYFLRYRRSTHVTPKSYLSFIQGYKTIYVEKRAEVQMLANRMNTGLQKLKEASESVAALSKELEVKEKELQIANEKADMVLKEVTVKAEASELVKVEVQKVKDKAQAIVDSITADKAIAEEKLEAARPALEEAEAALQTIKPSDIATVRTLSRPPPLIMQTMDCVLLLLRRRVNPVEINAETNFITSSWQESLNLMTSGSFLSELKQFPKDTINEETVELLQP-YFNLPNYNIERARTASSNVAGLLSWTKAMASFFAINKEVLPLKANL-----AVQENRLAVANLDLEKAQAELDAKQAELNVVRAEYEEAMTEKLTLLEDAKRCRRKMQIASNLISGLAGEKERWTEQSKEFAAQTKRLVGDVLLATAFLSYSGPFNQEFRSLLLNEWQCELKQRSIPFGNNLDITELLIDASTVSEWNLQGLPNDELSIHNGIIVTKAARFPLLIDPQTQGKTWIKNKEAKNELQITSLNHKYFRNHLEESLSLGRPLLIEDVGEELDPVLDNVLEKNFIKTGSTYKVKIGDKEVDVMKGFKLYMTTKLPNPAYTPEISARTSIIDFTVTIRGLEDQLLGRVILTEKREMEKERTDLLEDVTYNKRKMKELEDNLLYRLTSTQGSLVDDESLIVVLGNTKQTAEEVNQKLQIAGDTQIQINAAREEYRPVATRGSILYFLITEMSMVNVMYQTSLTQFLGLFDLSLARSSKSSN---TSERIKSIIEYMTFKVYYYAARGLYEEHKFLFTLLLTLKIDMQGKN---VTHKEFLTLIKGGASLDLKTCPQKPAE--WILDMSWLNLVE-LSKLWQFSEILDQVHHHEKLWKSWF-----DKEAPEEEVLPNSYQSLDCFR------RLLLIRCWCPDRTIAQARKYIRDAMGEKYTEGV--ILDVEGTWE-ESNPRTPLICFLSMGSDPTDSIIALGKKLKIETRYVSMGQGQEV-HARKLLQQTMANGGWALLQNCHLGLNFMDELMDTVIETECINDSFRLWITTEVHKNFPITLLQMSIKFTNEPPQGLKAGLKRTYGGINQDLLDVSNTNQWKPMLYCVAFLHSTVQERRKFGPLGWNIPYEFNQADFNATVQFIQNHLDD--MDTKQL----VSWNTVQYMIGEIQYGGRVTDDYDKRLLNTFSKVWFNKNMFERDFNFY------KGYGIPKCSSVDQYLAYIQGLPAYDTPEVFGLHPNADITFQSKQAKDVLDTILSIQPK---DSSSGGGETREAAVSRMADDM--------------LEKLPPDYIPFEVKRLQKMGPLKPMNIFLRQEIDRMQRVIMLVRSTLIDLKLAIDGTIIMSENLRDALDCMYDARIPARWMKESWASS-TLGFWFTELLERNRQF--------QTWLFKGRPNCFWMTGFFNPQGFLTAMKQEIARANKGWALDRMVLCNEVTKWMKDDIPHPPAKGVYVYGLYLEGASW-DRNNCRLTESKPKVLFEMMPVIWMYAENN----GSSEKKKKIVKDPRLYSCPIYKKPTRTDINCIASVGLKTTQPPEHWVLRGVAL 2682
BLAST of Cytoplasmic dynein 1 heavy chain 1 vs. Planmine SMEST
Match: SMESG000038602.1 (SMESG000038602.1) HSP 1 Score: 8390.4 bits (21770), Expect = 0.000e+0 Identity = 4077/4078 (99.98%), Postives = 4077/4078 (99.98%), Query Frame = 3 Query: 1815 MFRYFSRFNALFVRPHIRGAIGEYQTQLIQRVKDDIEALHNKFKVQYASSTACKMSKVRDLPPVSGSIIWVRQILRQLNAYMKRVEDVLGKDWAQHIEGQKLKADGESFKLKLNTSELFEEWSKKVAEKSLSVAGSIFNVESTRTVVTVRDREPQKITVLKLKVNFLPDVITLAKEVRNMRALGFRTPLSIVNKAHSANQLYPFAISLIESVRTYESTCSKIEEHKMQNISLLTAGLRKDVQLCIHEGVQITWESYRLDQYVQKLAELVFSFQEKVDDLVIVIKEIDFNVKALETCSYNKQTFEEILIRIQEAVDNMSLHQFSNLAQWVSNLDSLVEQRLIVRLEAGLLEWIKVLKGXXXXXXXXXXXXXXXVNSMAKHRLGGKPQIKKLIHELRITNQQMHLYPSIEVATQDILYQMSSWQNIILNLSRIVHSRYQVGLETESDNQKTYKKLLSSLPNSGESLENAYAAVHNILRDANEYVKTWTNYQSLWDLQGDQLFSLIADDNTVWMNVLEEIKSMRKHFDVAETQKEFGPLVIAFGKVQSKVSMKYDNWHKEVLTKFGQNMGKMMTTLYNEVQRARNELEQQSIDSGGTNESVNFITYTQNIKRKMNTWEKQAEACRAGQNILCRDRFQFPNDWLDSENIQGEWSAFKEIMRRKQETISSQVASLQMKITEEDKIVESKTTEVLGNWEKDKPIAGDLTPEEAVNIIQILEGKFNRLKEERENVQKAKEALELTEIGVKPISEEKVTNALSELHDLKNVWNELKSIWEKIRDMKETPWLSVQPRKLRQDIENLTAQLKELPNSFKQYASFEHVRTLLKMYMKVNASIVELKSEAIKERHWRMLMRKLNVSWSLNELQLGKVWDIDLVKNEEIIREVLAIAQGEKALEEYLRQITEVWKNYVLELTNYQSKSKIIKGWDDLFNKVKEHINNVTSMKASPYFKQFEEEATAWEDRLNKINALFDVWIDVQRRWIYLDGIFAGSADIKVLLPVESQRFQSVSTEFLGLMKKVQKSPLVTDVLNIANVQRQLERLADLLGKIQKSLGEYLERQRSSFPRFYFVGDEDLLEIIGNSXXXXXXXXXXXXMFAGVHSIILSEDEKVILGMMSKEGEELRFISPVSIIEHPRINDWLTAMEKEMRVSLAKYLNVAVKEISGWRTESNIDKDKFMVWLDKYQAQIVVLAAQITWSEAVEASLASGVSLESTMTVVHSTLNMLADTVLYEQPPVRRRKLEHLIIEYVHQRDVLRALHNDGVSSNKNFDWMSQMRFYFDPKQTDPLHQLSIHVANAKFHYGFEYLGVCDRLVQTPLTDRCYLTMTQALEARLGGSPFGPAGTGKTESVKSLGNQLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLSAVSQQIQGIQEALRELMVSKKDSINVELLGKQVHVNPDMAIFITMNPGYAGRSNLPDNLKKLFRSLAMTQPDRQLIAQVMLYSQGFRTAEVLAGKVVPFFKLCDEQLSPQSHYDFGLRALKSVLVSAGNVKRDRIKQEKEKIVARGEEINETAIAEQLPEQEILIQSVMETMVPKLIADDIPLLYSLLTDVFPGVEYRQAEMKRLREELRKVSENKFLVYSDEPNTAGYLWVEKVLQLYQITTIHHGLMMVGPSGSGKTMACRVLLQALENIDGIEGVAHIIDPKSISKDSLYGYMDPNTREWTDGLFTHILRRIIDSVRGESNKRQWIVFDGDVDPEWVENLNSVLDDNKLLTLPNGERLAIPPNVRIMFEVQDLKYATLATVSRCGMVWFSEEVLTTGMILTHFLNELKKVQVMEGEEDFSVNQGDTGADADSKISSSPIIQLQTQVSSILAPFFTEDGLIAKCLDYSTTLEHIMDFTRLRALTSLFSMIKQSIRNMIEYNQSHSDFPLNNEQIENYVAKSLISSVVWSMSGDSKLKVREQLSQYIKNISTVDLPTVGGIKNIIDFEVNIQGTWVAWSNKVPQIEVETHKITATDVVVPTMDTVRHEALLYTWLAEHRPVLLCGPPGSGKTMTLFSALRCLPDMEVVGLNFSSATTPELMLKTFDQYCEYRKTPNGIVLAPQQLNKWLIFFCDEINLPDMDKYGTQRVISFLRQMVEHHGFYRITDMQWVSFERIQFVGACNPPTDPGRKPLSHRFLRHVPVVYVDYPGETSLKQIYSTFNRAMLRMLPSLRGYADTLTNAMVEFFLKTQERFTHDMQPHYIYSPREMTRWVRGIHEALKPLESLSVEGLVRIWAHEALRLFQDRLVEEDERHWTDDNINEVALKHFPNINKEEALKRPILYSNWLSKDYSAVTQEELRDYVKARLKVFYEEELDVPLVLFNQVLDHVLRIDRVFRQPQGHLLLIGVSGAGKTTLSRFVSWINGLSVFQVKVHNKYTAEDFDEDLRNVLRRSGCKGEKITFIMDESNVMDSSFLERMNTLLANGEVPGLFEGDELTTLMTQCKEGAIREGLMIDSQEELYKWFTQQICRNLHVVFTMNPSADGLKDKASTSPALFNRCVLNWFGDWSLEAYFQVGKEFTNRLDLERTDYKVPDTLPCIAEGLLPQNPIYRDVVVNALVFVHQTMHQANVRVQKRGGRTAAITPRHYLDLIAHYMKLSAEKRADLEEQQLHLNNGLKKIEQTVDQVEVMQRSLTKKRQELENMNEAANAKLKQMVQDQQEAEQKKTTGQALKEELAKQEQFVNEKQKTVKQELDQVEPTVNEAKQAVQNIRKKDIQEIKAMKNPPNAVKMAVESICLLLGEKTTDWQSILKVIIKDTFVTSILNFNTDDVSDNTRETMKKKYLSNPDYNFEKVNKASNACGPMVKWVLAQISYADILKRVEPLRNELTELSDAAEQNRKKSQETEDLIAQLEKSIAKYTEEYATLISQAQTIKSDLASVESKVGRSVALLGSLSSERTRWDSGSETFKAQMATINGDCLLSSAFMAYGGYFDQHMRTSLFNTWCHHLSEADILFRSDLARVEYLSNPDDRLRWQANSLPADDLCVENAIILRRYNRYPLIIDPSGQATTFLLNEYKEKKITKTSFLDDSFRKTLESALRFGTPLLVQDVESYDPILNPVLNREVRRTGGRTLITLGDQDIDLSPTFTIFLSTRDPSVEFAPDICSRVTFVNFTVTRSSLQNQCLNAVLKIERPDIDQKRSDLLKAQGEFQLKLRHLEKDLLQSLNEAQGNLLENDKIIARLETLKREAADVAKKVEETDVVMQEVESVSTEYVPLAQSCSNIYFTLEAMNQIHFLYQYSLQLMLDIFSSVLINNPELTNVKAASDRLKIITKNLFQVTYNRLARGMLHEDQITFATILARIFLKGSTPIGFLENEFQHFLRSQEATITSSDSNKQDNLGLTLHQDQIDSVKRLKKLKVFAKIEEKVKSTKDIKNWTLTVTPESNVPELWVDDNNYNDEKLSKIAKGMYNLLIIQAIRPDRLLASTQKFIASVLGDTFTESVRGTLDLASIVEVEVTACVPILLCAVQGYDPSGRVEDLASEQGKQLTGIAIGSAEGFSQAEKAINSAAKTGKWVMLKNVHLATSWLVSLEKKIHSLQAHPNFRLFLTMEITPKLPVNLLRAGRVLVFEPPPGIKANLLRTLSSINNQRMSKEPVERSRLYFLLAWLNAIVQERLRYVPLGYSKKYEFGESDFKCALDTIDTWVDGAAMGRTNLPPEKIPWVALQTLLGSCIYGGKIDNAFDQRLLNSFLGYLFTEKCFDHNFALVSDADDGSNIAFPESTKHTDILQWVHKLPDLQTPSWLGLPNSAEKVLLTNLGQSLIGNILKMQQSLEDDEELVVGQSKTKRTIEVGDGRPAWMRQLYQSTQTWLQILPKSVTPLQRTIENIKDPMYRCFEREVNSGCNLLASVRKDLEDVAEVCKGAKKPTNHHRSMMADLAKGIIPKMWIRYAIPPGLTVIQWIQDFADRIKQLLHISDTAAKSGVIALRSIQVWLGGLFMAEAYITATRQSVAQNNKWALEELFLDVELGEGKVDSNTCVITGLRLMGSEIVDPRTLKLSTLIYKDIDICRLKWIRVEKSQQLEGSSAKDKVCLPIYLNAARSTVLFTLYFSTTDSSYDFYKRGVAI 14048 MFRYFSRFNALFVRPHIRGAIGEYQTQLIQRVKDDIEALHNKFKVQYASSTACKMSKVRDLPPVSGSIIWVRQILRQLNAYMKRVEDVLGKDWAQHIEGQKLKADGESFKLKLNTSELFEEWSKKVAEKSLSVAGSIFNVESTRTVVTVRDREPQKITVLKLKVNFLPDVITLAKEVRNMRALGFRTPLSIVNKAHSANQLYPFAISLIESVRTYESTCSKIEEHKMQNISLLTAGLRKDVQLCIHEGVQITWESYRLDQYVQKLAELVFSFQEKVDDLVIVIKEIDFNVKALETCSYNKQTFEEILIRIQEAVDNMSLHQFSNLAQWVSNLDSLVEQRLIVRLEAGLLEWIKVLKGENREDEEDDQDTDPDVNSMAKHRLGGKPQIKKLIHELRITNQQMHLYPSIEVATQDILYQMSSWQNIILNLSRIVHSRYQVGLETESDNQKTYKKLLSSLPNSGESLENAYAAVHNILRDANEYVKTWTNYQSLWDLQGDQLFSLIADDNTVWMNVLEEIKSMRKHFDVAETQKEFGPLVIAFGKVQSKVSMKYDNWHKEVLTKFGQNMGKMMTTLYNEVQRARNELEQQSIDSGGTNESVNFITYTQNIKRKMNTWEKQAEACRAGQNILCRDRFQFPNDWLDSENIQGEWSAFKEIMRRKQETISSQVASLQMKITEEDKIVESKTTEVLGNWEKDKPIAGDLTPEEAVNIIQILEGKFNRLKEERENVQKAKEALELTEIGVKPISEEKVTNALSELHDLKNVWNELKSIWEKIRDMKETPWLSVQPRKLRQDIENLTAQLKELPNSFKQYASFEHVRTLLKMYMKVNASIVELKSEAIKERHWRMLMRKLNVSWSLNELQLGKVWDIDLVKNEEIIREVLAIAQGEKALEEYLRQITEVWKNYVLELTNYQSKSKIIKGWDDLFNKVKEHINNVTSMKASPYFKQFEEEATAWEDRLNKINALFDVWIDVQRRWIYLDGIFAGSADIKVLLPVESQRFQSVSTEFLGLMKKVQKSPLVTDVLNIANVQRQLERLADLLGKIQKSLGEYLERQRSSFPRFYFVGDEDLLEIIGNSKDLKKLQKHFKKMFAGVHSIILSEDEKVILGMMSKEGEELRFISPVSIIEHPRINDWLTAMEKEMRVSLAKYLNVAVKEISGWRTESNIDKDKFMVWLDKYQAQIVVLAAQITWSEAVEASLASGVSLESTMTVVHSTLNMLADTVLYEQPPVRRRKLEHLIIEYVHQRDVLRALHNDGVSSNKNFDWMSQMRFYFDPKQTDPLHQLSIHVANAKFHYGFEYLGVCDRLVQTPLTDRCYLTMTQALEARLGGSPFGPAGTGKTESVKSLGNQLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLSAVSQQIQGIQEALRELMVSKKDSINVELLGKQVHVNPDMAIFITMNPGYAGRSNLPDNLKKLFRSLAMTQPDRQLIAQVMLYSQGFRTAEVLAGKVVPFFKLCDEQLSPQSHYDFGLRALKSVLVSAGNVKRDRIKQEKEKIVARGEEINETAIAEQLPEQEILIQSVMETMVPKLIADDIPLLYSLLTDVFPGVEYRQAEMKRLREELRKVSENKFLVYSDEPNTAGYLWVEKVLQLYQITTIHHGLMMVGPSGSGKTMACRVLLQALENIDGIEGVAHIIDPKSISKDSLYGYMDPNTREWTDGLFTHILRRIIDSVRGESNKRQWIVFDGDVDPEWVENLNSVLDDNKLLTLPNGERLAIPPNVRIMFEVQDLKYATLATVSRCGMVWFSEEVLTTGMILTHFLNELKKVQVMEGEEDFSVNQGDTGADADSKISSSPIIQLQTQVSSILAPFFTEDGLIAKCLDYSTTLEHIMDFTRLRALTSLFSMIKQSIRNMIEYNQSHSDFPLNNEQIENYVAKSLISSVVWSMSGDSKLKVREQLSQYIKNISTVDLPTVGGIKNIIDFEVNIQGTWVAWSNKVPQIEVETHKITATDVVVPTMDTVRHEALLYTWLAEHRPVLLCGPPGSGKTMTLFSALRCLPDMEVVGLNFSSATTPELMLKTFDQYCEYRKTPNGIVLAPQQLNKWLIFFCDEINLPDMDKYGTQRVISFLRQMVEHHGFYRITDMQWVSFERIQFVGACNPPTDPGRKPLSHRFLRHVPVVYVDYPGETSLKQIYSTFNRAMLRMLPSLRGYADTLTNAMVEFFLKTQERFTHDMQPHYIYSPREMTRWVRGIHEALKPLESLSVEGLVRIWAHEALRLFQDRLVEEDERHWTDDNINEVALKHFPNINKEEALKRPILYSNWLSKDYSAVTQEELRDYVKARLKVFYEEELDVPLVLFNQVLDHVLRIDRVFRQPQGHLLLIGVSGAGKTTLSRFVSWINGLSVFQVKVHNKYTAEDFDEDLRNVLRRSGCKGEKITFIMDESNVMDSSFLERMNTLLANGEVPGLFEGDELTTLMTQCKEGAIREGLMIDSQEELYKWFTQQICRNLHVVFTMNPSADGLKDKASTSPALFNRCVLNWFGDWSLEAYFQVGKEFTNRLDLERTDYKVPDTLPCIAEGLLPQNPIYRDVVVNALVFVHQTMHQANVRVQKRGGRTAAITPRHYLDLIAHYMKLSAEKRADLEEQQLHLNNGLKKIEQTVDQVEVMQRSLTKKRQELENMNEAANAKLKQMVQDQQEAEQKKTTGQALKEELAKQEQFVNEKQKTVKQELDQVEPTVNEAKQAVQNIRKKDIQEIKAMKNPPNAVKMAVESICLLLGEKTTDWQSILKVIIKDTFVTSILNFNTDDVSDNTRETMKKKYLSNPDYNFEKVNKASNACGPMVKWVLAQISYADILKRVEPLRNELTELSDAAEQNRKKSQETEDLIAQLEKSIAKYTEEYATLISQAQTIKSDLASVESKVGRSVALLGSLSSERTRWDSGSETFKAQMATINGDCLLSSAFMAYGGYFDQHMRTSLFNTWCHHLSEADILFRSDLARVEYLSNPDDRLRWQANSLPADDLCVENAIILRRYNRYPLIIDPSGQATTFLLNEYKEKKITKTSFLDDSFRKTLESALRFGTPLLVQDVESYDPILNPVLNREVRRTGGRTLITLGDQDIDLSPTFTIFLSTRDPSVEFAPDICSRVTFVNFTVTRSSLQNQCLNAVLKIERPDIDQKRSDLLKAQGEFQLKLRHLEKDLLQSLNEAQGNLLENDKIIARLETLKREAADVAKKVEETDVVMQEVESVSTEYVPLAQSCSNIYFTLEAMNQIHFLYQYSLQLMLDIFSSVLINNPEL NVKAASDRLKIITKNLFQVTYNRLARGMLHEDQITFATILARIFLKGSTPIGFLENEFQHFLRSQEATITSSDSNKQDNLGLTLHQDQIDSVKRLKKLKVFAKIEEKVKSTKDIKNWTLTVTPESNVPELWVDDNNYNDEKLSKIAKGMYNLLIIQAIRPDRLLASTQKFIASVLGDTFTESVRGTLDLASIVEVEVTACVPILLCAVQGYDPSGRVEDLASEQGKQLTGIAIGSAEGFSQAEKAINSAAKTGKWVMLKNVHLATSWLVSLEKKIHSLQAHPNFRLFLTMEITPKLPVNLLRAGRVLVFEPPPGIKANLLRTLSSINNQRMSKEPVERSRLYFLLAWLNAIVQERLRYVPLGYSKKYEFGESDFKCALDTIDTWVDGAAMGRTNLPPEKIPWVALQTLLGSCIYGGKIDNAFDQRLLNSFLGYLFTEKCFDHNFALVSDADDGSNIAFPESTKHTDILQWVHKLPDLQTPSWLGLPNSAEKVLLTNLGQSLIGNILKMQQSLEDDEELVVGQSKTKRTIEVGDGRPAWMRQLYQSTQTWLQILPKSVTPLQRTIENIKDPMYRCFEREVNSGCNLLASVRKDLEDVAEVCKGAKKPTNHHRSMMADLAKGIIPKMWIRYAIPPGLTVIQWIQDFADRIKQLLHISDTAAKSGVIALRSIQVWLGGLFMAEAYITATRQSVAQNNKWALEELFLDVELGEGKVDSNTCVITGLRLMGSEIVDPRTLKLSTLIYKDIDICRLKWIRVEKSQQLEGSSAKDKVCLPIYLNAARSTVLFTLYFSTTDSSYDFYKRGVAI Sbjct: 1 MFRYFSRFNALFVRPHIRGAIGEYQTQLIQRVKDDIEALHNKFKVQYASSTACKMSKVRDLPPVSGSIIWVRQILRQLNAYMKRVEDVLGKDWAQHIEGQKLKADGESFKLKLNTSELFEEWSKKVAEKSLSVAGSIFNVESTRTVVTVRDREPQKITVLKLKVNFLPDVITLAKEVRNMRALGFRTPLSIVNKAHSANQLYPFAISLIESVRTYESTCSKIEEHKMQNISLLTAGLRKDVQLCIHEGVQITWESYRLDQYVQKLAELVFSFQEKVDDLVIVIKEIDFNVKALETCSYNKQTFEEILIRIQEAVDNMSLHQFSNLAQWVSNLDSLVEQRLIVRLEAGLLEWIKVLKGENREDEEDDQDTDPDVNSMAKHRLGGKPQIKKLIHELRITNQQMHLYPSIEVATQDILYQMSSWQNIILNLSRIVHSRYQVGLETESDNQKTYKKLLSSLPNSGESLENAYAAVHNILRDANEYVKTWTNYQSLWDLQGDQLFSLIADDNTVWMNVLEEIKSMRKHFDVAETQKEFGPLVIAFGKVQSKVSMKYDNWHKEVLTKFGQNMGKMMTTLYNEVQRARNELEQQSIDSGGTNESVNFITYTQNIKRKMNTWEKQAEACRAGQNILCRDRFQFPNDWLDSENIQGEWSAFKEIMRRKQETISSQVASLQMKITEEDKIVESKTTEVLGNWEKDKPIAGDLTPEEAVNIIQILEGKFNRLKEERENVQKAKEALELTEIGVKPISEEKVTNALSELHDLKNVWNELKSIWEKIRDMKETPWLSVQPRKLRQDIENLTAQLKELPNSFKQYASFEHVRTLLKMYMKVNASIVELKSEAIKERHWRMLMRKLNVSWSLNELQLGKVWDIDLVKNEEIIREVLAIAQGEKALEEYLRQITEVWKNYVLELTNYQSKSKIIKGWDDLFNKVKEHINNVTSMKASPYFKQFEEEATAWEDRLNKINALFDVWIDVQRRWIYLDGIFAGSADIKVLLPVESQRFQSVSTEFLGLMKKVQKSPLVTDVLNIANVQRQLERLADLLGKIQKSLGEYLERQRSSFPRFYFVGDEDLLEIIGNSKDLKKLQKHFKKMFAGVHSIILSEDEKVILGMMSKEGEELRFISPVSIIEHPRINDWLTAMEKEMRVSLAKYLNVAVKEISGWRTESNIDKDKFMVWLDKYQAQIVVLAAQITWSEAVEASLASGVSLESTMTVVHSTLNMLADTVLYEQPPVRRRKLEHLIIEYVHQRDVLRALHNDGVSSNKNFDWMSQMRFYFDPKQTDPLHQLSIHVANAKFHYGFEYLGVCDRLVQTPLTDRCYLTMTQALEARLGGSPFGPAGTGKTESVKSLGNQLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLSAVSQQIQGIQEALRELMVSKKDSINVELLGKQVHVNPDMAIFITMNPGYAGRSNLPDNLKKLFRSLAMTQPDRQLIAQVMLYSQGFRTAEVLAGKVVPFFKLCDEQLSPQSHYDFGLRALKSVLVSAGNVKRDRIKQEKEKIVARGEEINETAIAEQLPEQEILIQSVMETMVPKLIADDIPLLYSLLTDVFPGVEYRQAEMKRLREELRKVSENKFLVYSDEPNTAGYLWVEKVLQLYQITTIHHGLMMVGPSGSGKTMACRVLLQALENIDGIEGVAHIIDPKSISKDSLYGYMDPNTREWTDGLFTHILRRIIDSVRGESNKRQWIVFDGDVDPEWVENLNSVLDDNKLLTLPNGERLAIPPNVRIMFEVQDLKYATLATVSRCGMVWFSEEVLTTGMILTHFLNELKKVQVMEGEEDFSVNQGDTGADADSKISSSPIIQLQTQVSSILAPFFTEDGLIAKCLDYSTTLEHIMDFTRLRALTSLFSMIKQSIRNMIEYNQSHSDFPLNNEQIENYVAKSLISSVVWSMSGDSKLKVREQLSQYIKNISTVDLPTVGGIKNIIDFEVNIQGTWVAWSNKVPQIEVETHKITATDVVVPTMDTVRHEALLYTWLAEHRPVLLCGPPGSGKTMTLFSALRCLPDMEVVGLNFSSATTPELMLKTFDQYCEYRKTPNGIVLAPQQLNKWLIFFCDEINLPDMDKYGTQRVISFLRQMVEHHGFYRITDMQWVSFERIQFVGACNPPTDPGRKPLSHRFLRHVPVVYVDYPGETSLKQIYSTFNRAMLRMLPSLRGYADTLTNAMVEFFLKTQERFTHDMQPHYIYSPREMTRWVRGIHEALKPLESLSVEGLVRIWAHEALRLFQDRLVEEDERHWTDDNINEVALKHFPNINKEEALKRPILYSNWLSKDYSAVTQEELRDYVKARLKVFYEEELDVPLVLFNQVLDHVLRIDRVFRQPQGHLLLIGVSGAGKTTLSRFVSWINGLSVFQVKVHNKYTAEDFDEDLRNVLRRSGCKGEKITFIMDESNVMDSSFLERMNTLLANGEVPGLFEGDELTTLMTQCKEGAIREGLMIDSQEELYKWFTQQICRNLHVVFTMNPSADGLKDKASTSPALFNRCVLNWFGDWSLEAYFQVGKEFTNRLDLERTDYKVPDTLPCIAEGLLPQNPIYRDVVVNALVFVHQTMHQANVRVQKRGGRTAAITPRHYLDLIAHYMKLSAEKRADLEEQQLHLNNGLKKIEQTVDQVEVMQRSLTKKRQELENMNEAANAKLKQMVQDQQEAEQKKTTGQALKEELAKQEQFVNEKQKTVKQELDQVEPTVNEAKQAVQNIRKKDIQEIKAMKNPPNAVKMAVESICLLLGEKTTDWQSILKVIIKDTFVTSILNFNTDDVSDNTRETMKKKYLSNPDYNFEKVNKASNACGPMVKWVLAQISYADILKRVEPLRNELTELSDAAEQNRKKSQETEDLIAQLEKSIAKYTEEYATLISQAQTIKSDLASVESKVGRSVALLGSLSSERTRWDSGSETFKAQMATINGDCLLSSAFMAYGGYFDQHMRTSLFNTWCHHLSEADILFRSDLARVEYLSNPDDRLRWQANSLPADDLCVENAIILRRYNRYPLIIDPSGQATTFLLNEYKEKKITKTSFLDDSFRKTLESALRFGTPLLVQDVESYDPILNPVLNREVRRTGGRTLITLGDQDIDLSPTFTIFLSTRDPSVEFAPDICSRVTFVNFTVTRSSLQNQCLNAVLKIERPDIDQKRSDLLKAQGEFQLKLRHLEKDLLQSLNEAQGNLLENDKIIARLETLKREAADVAKKVEETDVVMQEVESVSTEYVPLAQSCSNIYFTLEAMNQIHFLYQYSLQLMLDIFSSVLINNPELANVKAASDRLKIITKNLFQVTYNRLARGMLHEDQITFATILARIFLKGSTPIGFLENEFQHFLRSQEATITSSDSNKQDNLGLTLHQDQIDSVKRLKKLKVFAKIEEKVKSTKDIKNWTLTVTPESNVPELWVDDNNYNDEKLSKIAKGMYNLLIIQAIRPDRLLASTQKFIASVLGDTFTESVRGTLDLASIVEVEVTACVPILLCAVQGYDPSGRVEDLASEQGKQLTGIAIGSAEGFSQAEKAINSAAKTGKWVMLKNVHLATSWLVSLEKKIHSLQAHPNFRLFLTMEITPKLPVNLLRAGRVLVFEPPPGIKANLLRTLSSINNQRMSKEPVERSRLYFLLAWLNAIVQERLRYVPLGYSKKYEFGESDFKCALDTIDTWVDGAAMGRTNLPPEKIPWVALQTLLGSCIYGGKIDNAFDQRLLNSFLGYLFTEKCFDHNFALVSDADDGSNIAFPESTKHTDILQWVHKLPDLQTPSWLGLPNSAEKVLLTNLGQSLIGNILKMQQSLEDDEELVVGQSKTKRTIEVGDGRPAWMRQLYQSTQTWLQILPKSVTPLQRTIENIKDPMYRCFEREVNSGCNLLASVRKDLEDVAEVCKGAKKPTNHHRSMMADLAKGIIPKMWIRYAIPPGLTVIQWIQDFADRIKQLLHISDTAAKSGVIALRSIQVWLGGLFMAEAYITATRQSVAQNNKWALEELFLDVELGEGKVDSNTCVITGLRLMGSEIVDPRTLKLSTLIYKDIDICRLKWIRVEKSQQLEGSSAKDKVCLPIYLNAARSTVLFTLYFSTTDSSYDFYKRGVAI 4078
BLAST of Cytoplasmic dynein 1 heavy chain 1 vs. Planmine SMEST
Match: SMESG000038602.1 (SMESG000038602.1) HSP 1 Score: 8383.85 bits (21753), Expect = 0.000e+0 Identity = 4077/4104 (99.34%), Postives = 4077/4104 (99.34%), Query Frame = 3 Query: 1815 MFRYFSRFNALFVRPHIRGAIGEYQTQLIQRVKDDIEALHNKFKVQYASSTACKMSKVRDLPPVSGSIIWVRQILRQLNAYMKRVEDVLGKDWAQHIEGQKLKADGESFKLKLNTSELFEEWSKKVAEKSLSVAGSIFNVESTRTVVTVRDREPQKITVLKLKVNFLPDVITLAKEVRNMRALGFRTPLSIVNKAHSANQLYPFAISLIESVRTYESTCSKIEEHKMQNISLLTAGLRKDVQLCIHEGVQITWESYRLDQYVQKLAELVFSFQEKVDDLVIVIKEIDFNVKALETCSYNKQTFEEILIRIQEAVDNMSLHQFSNLAQWVSNLDSLVEQRLIVRLEAGLLEWIKVLKGXXXXXXXXXXXXXXXVNSMAKHRLGGKPQIKKLIHELRITNQQMHLYPSIEVATQDILYQMSSWQNIILNLSRIVHSRYQVGLETESDNQKTYKKLLSSLPNSGESLENAYAAVHNILRDANEYVKTWTNYQSLWDLQGDQLFSLIADDNTVWMNVLEEIKSMRKHFDVAETQKEFGPLVIAFGKVQSKVSMKYDNWHKEVLTKFGQNMGKMMTTLYNEVQRARNELEQQSIDSGGTNESVNFITYTQNIKRKMNTWEKQAEACRAGQNILCRDRFQFPNDWLDSENIQGEWSAFKEIMRRKQETISSQVASLQMKITEEDKIVESKTTEVLGNWEKDKPIAGDLTPEEAVNIIQILEGKFNRLKEERENVQKAKEALELTEIGVKPISEEKVTNALSELHDLKNVWNELKSIWEKIRDMKETPWLSVQPRKLRQDIENLTAQLKELPNSFKQYASFEHVRTLLKMYMKVNASIVELKSEAIKERHWRMLMRKLNVSWSLNELQLGKVWDIDLVKNEEIIREVLAIAQGEKALEEYLRQITEVWKNYVLELTNYQSKSKIIKGWDDLFNKVKEHINNVTSMKASPYFKQFEEEATAWEDRLNKINALFDVWIDVQRRWIYLDGIFAGSADIKVLLPVESQRFQSVSTEFLGLMKKVQKSPLVTDVLNIANVQRQLERLADLLGKIQKSLGEYLERQRSSFPRFYFVGDEDLLEIIGNSXXXXXXXXXXXXMFAGVHSIILSEDEKVILGMMSKEGEELRFISPVSIIEHPRINDWLTAMEKEMRVSLAKYLNVAVKEISGWRTESNIDKDKFMVWLDKYQAQIVVLAAQITWSEAVEASLASGVSLESTMTVVHSTLNMLADTVLYEQPPVRRRKLEHLIIEYVHQRDVLRALHNDGVSSNKNFDWMSQMRFYFDPKQTDPLHQLSIHVANAKFHYGFEYLGVCDRLVQTPLTDRCYLTMTQALEARLGGSPFGPAGTGKTESVKSLGNQLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLSAVSQQIQGIQEALRELMVSKKDSINVELLGKQVHVNPDMAIFITMNPGYAGRSNLPDNLKKLFRSLAMTQPDRQLIAQVMLYSQGFRTAEVLAGKVVPFFKLCDEQLSPQSHYDFGLRALKSVLVSAGNVKRDRIKQEKEKIVARGEEINETAIAEQLPEQEILIQSVMETMVPKLIADDIPLLYSLLTDVFPGVEYRQAEMKRLREELRKVSENKFLVYSDEPNTAGYLWVEKVLQLYQITTIHHGLMMVGPSGSGKTMACRVLLQALENIDGIEGVAHIIDPKSISKDSLYGYMDPNTREWTDGLFTHILRRIIDSVRGESNKRQWIVFDGDVDPEWVENLNSVLDDNKLLTLPNGERLAIPPNVRIMFEVQDLKYATLATVSRCGMVWFSEEVLTTGMILTHFLNELKKVQVMEGEEDFSVNQGDTGADADSKISSSPIIQLQTQVSSILAPFFTEDGLIAKCLDYSTTLEHIMDFTRLRALTSLFSMIKQSIRNMIEYNQSHSDFPLNNEQIENYVAKSLISSVVWSMSGDSKLKVREQLSQYIKNISTVDLPTVGGIKNIIDFEVNIQGTWVAWSNKVPQIEVETHKITATDVVVPTMDTVRHEALLYTWLAEHRPVLLCGPPGSGKTMTLFSALRCLPDMEVVGLNFSSATTPELMLKTFDQYCEYRKTPNGIVLAPQQLNKWLIFFCDEINLPDMDKYGTQRVISFLRQMVEHHGFYRITDMQWVSFERIQFVGACNPPTDPGRKPLSHRFLRHVPVVYVDYPGETSLKQIYSTFNRAMLRMLPSLRGYADTLTNAMVEFFLKTQERFTHDMQPHYIYSPREMTRWVRGIHEALKPLESLSVEGLVRIWAHEALRLFQDRLVEEDERHWTDDNINEVALKHFPNINKEEALKRPILYSNWLSKDYSAVTQEELRDYVKARLKVFYEEELDVPLVLFNQVLDHVLRIDRVFRQPQGHLLLIGVSGAGKTTLSRFVSWINGLSVFQVKVHNKYTAEDFDEDLRNVLRRSGCKGEKITFIMDESNVMDSSFLERMNTLLANGEVPGLFEGDELTTLMTQCKEGAIREGLMIDSQEELYKWFTQQICRNLHVVFTMNPSADGLKDKASTSPALFNRCVLNWFGDWSLEAYFQVGKEFTNRLDLERTDYKVPDTLPCIAEGLLPQNPIYRDVVVNALVFVHQTMHQANVRVQKRGGRTAAITPRHYLDLIAHYMKLSAEKRADLEEQQLHLNNGLKKIEQTVDQVEVMQRSLTKKRQELENMNEAANAKLKQMVQDQQEAEQKKTTGQALKEELAKQEQFVNEKQKTVKQELDQVEPTVNEAKQAVQNIRKKDIQEIKAMKNPPNAVKMAVESICLLLGEKTTDWQSILKVIIKDTFVTSILNFNTDDVSDNTRETMKKKYLSNPDYNFEKVNKASNACGPMVKWVLAQISYADILKRVEPLRNELTELSDAAEQNRKKSQETEDLIAQLEKSIAKYTEEYATLISQAQTIKSDLASVESKVGRSVALLGSLSSERTRWDSGSETFKAQMATINGDCLLSSAFMAYGGYFDQHMRTSLFNTWCHHLSEADILFRSDLARVEYLSNPDDRLRWQANSLPADDLCVENAIILRRYNRYPLIIDPSGQATTFLLNEYKEKKITKTSFLDDSFRKTLESALRFGTPLLVQDVESYDPILNPVLNREVRRTGGRTLITLGDQDIDLSPTFTIFLSTRDPSVEFAPDICSRVTFVNFTVTRSSLQNQCLNAVLKIERPDIDQKRSDLLKAQGEFQLKLRHLEKDLLQSLNEAQGNLLENDKIIARLETLKREAADVAKKVEETDVVMQEVESVSTEYVPLAQSCSNIYFTLEAMNQIHFLYQYSLQLMLDIFSSVLINNPELTNVKAASDRLKIITKNLFQVTYNRLARGMLHEDQITFATILARIFLKGSTPIGFLENEFQHFLRSQEATITSSDSNKQDNLGLTLHQDQIDSVKRLKKLKVFAKIEEKVKSTKDIKNWTLTVTPESNVPELWVDDNNYNDEKLSKIAKGMYNLLIIQAIRPDRLLASTQKFIASVLGDTFTESVRGTLDLASIVEVEVTACVPILLCAVQGYDPSGRVEDLASEQGKQLTGIAIGSAEGFSQAEKAINSAAKTGKWVMLKNVHLATSWLVSLEKKIHSLQAHPNFRLFLTMEITPKLPVNLLRAGRVLVFEPPPGIKANLLRTLSSINNQRMSKEPVERSRLYFLLAWLNAIVQERLRYVPLGYSKKYEFGESDFKCALDTIDTWVDGAAMGRTNLPPEKIPWVALQTLLGSCIYGGKIDNAFDQRLLNSFLGYLFTEKCFDHNFALVSDADDGSNIAFPESTKHTDILQWVHKLPDLQTPSWLGLPNSAEKVLLTNL--------------------------GQSLIGNILKMQQSLEDDEELVVGQSKTKRTIEVGDGRPAWMRQLYQSTQTWLQILPKSVTPLQRTIENIKDPMYRCFEREVNSGCNLLASVRKDLEDVAEVCKGAKKPTNHHRSMMADLAKGIIPKMWIRYAIPPGLTVIQWIQDFADRIKQLLHISDTAAKSGVIALRSIQVWLGGLFMAEAYITATRQSVAQNNKWALEELFLDVELGEGKVDSNTCVITGLRLMGSEIVDPRTLKLSTLIYKDIDICRLKWIRVEKSQQLEGSSAKDKVCLPIYLNAARSTVLFTLYFSTTDSSYDFYKRGVAI 14048 MFRYFSRFNALFVRPHIRGAIGEYQTQLIQRVKDDIEALHNKFKVQYASSTACKMSKVRDLPPVSGSIIWVRQILRQLNAYMKRVEDVLGKDWAQHIEGQKLKADGESFKLKLNTSELFEEWSKKVAEKSLSVAGSIFNVESTRTVVTVRDREPQKITVLKLKVNFLPDVITLAKEVRNMRALGFRTPLSIVNKAHSANQLYPFAISLIESVRTYESTCSKIEEHKMQNISLLTAGLRKDVQLCIHEGVQITWESYRLDQYVQKLAELVFSFQEKVDDLVIVIKEIDFNVKALETCSYNKQTFEEILIRIQEAVDNMSLHQFSNLAQWVSNLDSLVEQRLIVRLEAGLLEWIKVLKGENREDEEDDQDTDPDVNSMAKHRLGGKPQIKKLIHELRITNQQMHLYPSIEVATQDILYQMSSWQNIILNLSRIVHSRYQVGLETESDNQKTYKKLLSSLPNSGESLENAYAAVHNILRDANEYVKTWTNYQSLWDLQGDQLFSLIADDNTVWMNVLEEIKSMRKHFDVAETQKEFGPLVIAFGKVQSKVSMKYDNWHKEVLTKFGQNMGKMMTTLYNEVQRARNELEQQSIDSGGTNESVNFITYTQNIKRKMNTWEKQAEACRAGQNILCRDRFQFPNDWLDSENIQGEWSAFKEIMRRKQETISSQVASLQMKITEEDKIVESKTTEVLGNWEKDKPIAGDLTPEEAVNIIQILEGKFNRLKEERENVQKAKEALELTEIGVKPISEEKVTNALSELHDLKNVWNELKSIWEKIRDMKETPWLSVQPRKLRQDIENLTAQLKELPNSFKQYASFEHVRTLLKMYMKVNASIVELKSEAIKERHWRMLMRKLNVSWSLNELQLGKVWDIDLVKNEEIIREVLAIAQGEKALEEYLRQITEVWKNYVLELTNYQSKSKIIKGWDDLFNKVKEHINNVTSMKASPYFKQFEEEATAWEDRLNKINALFDVWIDVQRRWIYLDGIFAGSADIKVLLPVESQRFQSVSTEFLGLMKKVQKSPLVTDVLNIANVQRQLERLADLLGKIQKSLGEYLERQRSSFPRFYFVGDEDLLEIIGNSKDLKKLQKHFKKMFAGVHSIILSEDEKVILGMMSKEGEELRFISPVSIIEHPRINDWLTAMEKEMRVSLAKYLNVAVKEISGWRTESNIDKDKFMVWLDKYQAQIVVLAAQITWSEAVEASLASGVSLESTMTVVHSTLNMLADTVLYEQPPVRRRKLEHLIIEYVHQRDVLRALHNDGVSSNKNFDWMSQMRFYFDPKQTDPLHQLSIHVANAKFHYGFEYLGVCDRLVQTPLTDRCYLTMTQALEARLGGSPFGPAGTGKTESVKSLGNQLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLSAVSQQIQGIQEALRELMVSKKDSINVELLGKQVHVNPDMAIFITMNPGYAGRSNLPDNLKKLFRSLAMTQPDRQLIAQVMLYSQGFRTAEVLAGKVVPFFKLCDEQLSPQSHYDFGLRALKSVLVSAGNVKRDRIKQEKEKIVARGEEINETAIAEQLPEQEILIQSVMETMVPKLIADDIPLLYSLLTDVFPGVEYRQAEMKRLREELRKVSENKFLVYSDEPNTAGYLWVEKVLQLYQITTIHHGLMMVGPSGSGKTMACRVLLQALENIDGIEGVAHIIDPKSISKDSLYGYMDPNTREWTDGLFTHILRRIIDSVRGESNKRQWIVFDGDVDPEWVENLNSVLDDNKLLTLPNGERLAIPPNVRIMFEVQDLKYATLATVSRCGMVWFSEEVLTTGMILTHFLNELKKVQVMEGEEDFSVNQGDTGADADSKISSSPIIQLQTQVSSILAPFFTEDGLIAKCLDYSTTLEHIMDFTRLRALTSLFSMIKQSIRNMIEYNQSHSDFPLNNEQIENYVAKSLISSVVWSMSGDSKLKVREQLSQYIKNISTVDLPTVGGIKNIIDFEVNIQGTWVAWSNKVPQIEVETHKITATDVVVPTMDTVRHEALLYTWLAEHRPVLLCGPPGSGKTMTLFSALRCLPDMEVVGLNFSSATTPELMLKTFDQYCEYRKTPNGIVLAPQQLNKWLIFFCDEINLPDMDKYGTQRVISFLRQMVEHHGFYRITDMQWVSFERIQFVGACNPPTDPGRKPLSHRFLRHVPVVYVDYPGETSLKQIYSTFNRAMLRMLPSLRGYADTLTNAMVEFFLKTQERFTHDMQPHYIYSPREMTRWVRGIHEALKPLESLSVEGLVRIWAHEALRLFQDRLVEEDERHWTDDNINEVALKHFPNINKEEALKRPILYSNWLSKDYSAVTQEELRDYVKARLKVFYEEELDVPLVLFNQVLDHVLRIDRVFRQPQGHLLLIGVSGAGKTTLSRFVSWINGLSVFQVKVHNKYTAEDFDEDLRNVLRRSGCKGEKITFIMDESNVMDSSFLERMNTLLANGEVPGLFEGDELTTLMTQCKEGAIREGLMIDSQEELYKWFTQQICRNLHVVFTMNPSADGLKDKASTSPALFNRCVLNWFGDWSLEAYFQVGKEFTNRLDLERTDYKVPDTLPCIAEGLLPQNPIYRDVVVNALVFVHQTMHQANVRVQKRGGRTAAITPRHYLDLIAHYMKLSAEKRADLEEQQLHLNNGLKKIEQTVDQVEVMQRSLTKKRQELENMNEAANAKLKQMVQDQQEAEQKKTTGQALKEELAKQEQFVNEKQKTVKQELDQVEPTVNEAKQAVQNIRKKDIQEIKAMKNPPNAVKMAVESICLLLGEKTTDWQSILKVIIKDTFVTSILNFNTDDVSDNTRETMKKKYLSNPDYNFEKVNKASNACGPMVKWVLAQISYADILKRVEPLRNELTELSDAAEQNRKKSQETEDLIAQLEKSIAKYTEEYATLISQAQTIKSDLASVESKVGRSVALLGSLSSERTRWDSGSETFKAQMATINGDCLLSSAFMAYGGYFDQHMRTSLFNTWCHHLSEADILFRSDLARVEYLSNPDDRLRWQANSLPADDLCVENAIILRRYNRYPLIIDPSGQATTFLLNEYKEKKITKTSFLDDSFRKTLESALRFGTPLLVQDVESYDPILNPVLNREVRRTGGRTLITLGDQDIDLSPTFTIFLSTRDPSVEFAPDICSRVTFVNFTVTRSSLQNQCLNAVLKIERPDIDQKRSDLLKAQGEFQLKLRHLEKDLLQSLNEAQGNLLENDKIIARLETLKREAADVAKKVEETDVVMQEVESVSTEYVPLAQSCSNIYFTLEAMNQIHFLYQYSLQLMLDIFSSVLINNPEL NVKAASDRLKIITKNLFQVTYNRLARGMLHEDQITFATILARIFLKGSTPIGFLENEFQHFLRSQEATITSSDSNKQDNLGLTLHQDQIDSVKRLKKLKVFAKIEEKVKSTKDIKNWTLTVTPESNVPELWVDDNNYNDEKLSKIAKGMYNLLIIQAIRPDRLLASTQKFIASVLGDTFTESVRGTLDLASIVEVEVTACVPILLCAVQGYDPSGRVEDLASEQGKQLTGIAIGSAEGFSQAEKAINSAAKTGKWVMLKNVHLATSWLVSLEKKIHSLQAHPNFRLFLTMEITPKLPVNLLRAGRVLVFEPPPGIKANLLRTLSSINNQRMSKEPVERSRLYFLLAWLNAIVQERLRYVPLGYSKKYEFGESDFKCALDTIDTWVDGAAMGRTNLPPEKIPWVALQTLLGSCIYGGKIDNAFDQRLLNSFLGYLFTEKCFDHNFALVSDADDGSNIAFPESTKHTDILQWVHKLPDLQTPSWLGLPNSAEKVLLTNL GQSLIGNILKMQQSLEDDEELVVGQSKTKRTIEVGDGRPAWMRQLYQSTQTWLQILPKSVTPLQRTIENIKDPMYRCFEREVNSGCNLLASVRKDLEDVAEVCKGAKKPTNHHRSMMADLAKGIIPKMWIRYAIPPGLTVIQWIQDFADRIKQLLHISDTAAKSGVIALRSIQVWLGGLFMAEAYITATRQSVAQNNKWALEELFLDVELGEGKVDSNTCVITGLRLMGSEIVDPRTLKLSTLIYKDIDICRLKWIRVEKSQQLEGSSAKDKVCLPIYLNAARSTVLFTLYFSTTDSSYDFYKRGVAI Sbjct: 1 MFRYFSRFNALFVRPHIRGAIGEYQTQLIQRVKDDIEALHNKFKVQYASSTACKMSKVRDLPPVSGSIIWVRQILRQLNAYMKRVEDVLGKDWAQHIEGQKLKADGESFKLKLNTSELFEEWSKKVAEKSLSVAGSIFNVESTRTVVTVRDREPQKITVLKLKVNFLPDVITLAKEVRNMRALGFRTPLSIVNKAHSANQLYPFAISLIESVRTYESTCSKIEEHKMQNISLLTAGLRKDVQLCIHEGVQITWESYRLDQYVQKLAELVFSFQEKVDDLVIVIKEIDFNVKALETCSYNKQTFEEILIRIQEAVDNMSLHQFSNLAQWVSNLDSLVEQRLIVRLEAGLLEWIKVLKGENREDEEDDQDTDPDVNSMAKHRLGGKPQIKKLIHELRITNQQMHLYPSIEVATQDILYQMSSWQNIILNLSRIVHSRYQVGLETESDNQKTYKKLLSSLPNSGESLENAYAAVHNILRDANEYVKTWTNYQSLWDLQGDQLFSLIADDNTVWMNVLEEIKSMRKHFDVAETQKEFGPLVIAFGKVQSKVSMKYDNWHKEVLTKFGQNMGKMMTTLYNEVQRARNELEQQSIDSGGTNESVNFITYTQNIKRKMNTWEKQAEACRAGQNILCRDRFQFPNDWLDSENIQGEWSAFKEIMRRKQETISSQVASLQMKITEEDKIVESKTTEVLGNWEKDKPIAGDLTPEEAVNIIQILEGKFNRLKEERENVQKAKEALELTEIGVKPISEEKVTNALSELHDLKNVWNELKSIWEKIRDMKETPWLSVQPRKLRQDIENLTAQLKELPNSFKQYASFEHVRTLLKMYMKVNASIVELKSEAIKERHWRMLMRKLNVSWSLNELQLGKVWDIDLVKNEEIIREVLAIAQGEKALEEYLRQITEVWKNYVLELTNYQSKSKIIKGWDDLFNKVKEHINNVTSMKASPYFKQFEEEATAWEDRLNKINALFDVWIDVQRRWIYLDGIFAGSADIKVLLPVESQRFQSVSTEFLGLMKKVQKSPLVTDVLNIANVQRQLERLADLLGKIQKSLGEYLERQRSSFPRFYFVGDEDLLEIIGNSKDLKKLQKHFKKMFAGVHSIILSEDEKVILGMMSKEGEELRFISPVSIIEHPRINDWLTAMEKEMRVSLAKYLNVAVKEISGWRTESNIDKDKFMVWLDKYQAQIVVLAAQITWSEAVEASLASGVSLESTMTVVHSTLNMLADTVLYEQPPVRRRKLEHLIIEYVHQRDVLRALHNDGVSSNKNFDWMSQMRFYFDPKQTDPLHQLSIHVANAKFHYGFEYLGVCDRLVQTPLTDRCYLTMTQALEARLGGSPFGPAGTGKTESVKSLGNQLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLSAVSQQIQGIQEALRELMVSKKDSINVELLGKQVHVNPDMAIFITMNPGYAGRSNLPDNLKKLFRSLAMTQPDRQLIAQVMLYSQGFRTAEVLAGKVVPFFKLCDEQLSPQSHYDFGLRALKSVLVSAGNVKRDRIKQEKEKIVARGEEINETAIAEQLPEQEILIQSVMETMVPKLIADDIPLLYSLLTDVFPGVEYRQAEMKRLREELRKVSENKFLVYSDEPNTAGYLWVEKVLQLYQITTIHHGLMMVGPSGSGKTMACRVLLQALENIDGIEGVAHIIDPKSISKDSLYGYMDPNTREWTDGLFTHILRRIIDSVRGESNKRQWIVFDGDVDPEWVENLNSVLDDNKLLTLPNGERLAIPPNVRIMFEVQDLKYATLATVSRCGMVWFSEEVLTTGMILTHFLNELKKVQVMEGEEDFSVNQGDTGADADSKISSSPIIQLQTQVSSILAPFFTEDGLIAKCLDYSTTLEHIMDFTRLRALTSLFSMIKQSIRNMIEYNQSHSDFPLNNEQIENYVAKSLISSVVWSMSGDSKLKVREQLSQYIKNISTVDLPTVGGIKNIIDFEVNIQGTWVAWSNKVPQIEVETHKITATDVVVPTMDTVRHEALLYTWLAEHRPVLLCGPPGSGKTMTLFSALRCLPDMEVVGLNFSSATTPELMLKTFDQYCEYRKTPNGIVLAPQQLNKWLIFFCDEINLPDMDKYGTQRVISFLRQMVEHHGFYRITDMQWVSFERIQFVGACNPPTDPGRKPLSHRFLRHVPVVYVDYPGETSLKQIYSTFNRAMLRMLPSLRGYADTLTNAMVEFFLKTQERFTHDMQPHYIYSPREMTRWVRGIHEALKPLESLSVEGLVRIWAHEALRLFQDRLVEEDERHWTDDNINEVALKHFPNINKEEALKRPILYSNWLSKDYSAVTQEELRDYVKARLKVFYEEELDVPLVLFNQVLDHVLRIDRVFRQPQGHLLLIGVSGAGKTTLSRFVSWINGLSVFQVKVHNKYTAEDFDEDLRNVLRRSGCKGEKITFIMDESNVMDSSFLERMNTLLANGEVPGLFEGDELTTLMTQCKEGAIREGLMIDSQEELYKWFTQQICRNLHVVFTMNPSADGLKDKASTSPALFNRCVLNWFGDWSLEAYFQVGKEFTNRLDLERTDYKVPDTLPCIAEGLLPQNPIYRDVVVNALVFVHQTMHQANVRVQKRGGRTAAITPRHYLDLIAHYMKLSAEKRADLEEQQLHLNNGLKKIEQTVDQVEVMQRSLTKKRQELENMNEAANAKLKQMVQDQQEAEQKKTTGQALKEELAKQEQFVNEKQKTVKQELDQVEPTVNEAKQAVQNIRKKDIQEIKAMKNPPNAVKMAVESICLLLGEKTTDWQSILKVIIKDTFVTSILNFNTDDVSDNTRETMKKKYLSNPDYNFEKVNKASNACGPMVKWVLAQISYADILKRVEPLRNELTELSDAAEQNRKKSQETEDLIAQLEKSIAKYTEEYATLISQAQTIKSDLASVESKVGRSVALLGSLSSERTRWDSGSETFKAQMATINGDCLLSSAFMAYGGYFDQHMRTSLFNTWCHHLSEADILFRSDLARVEYLSNPDDRLRWQANSLPADDLCVENAIILRRYNRYPLIIDPSGQATTFLLNEYKEKKITKTSFLDDSFRKTLESALRFGTPLLVQDVESYDPILNPVLNREVRRTGGRTLITLGDQDIDLSPTFTIFLSTRDPSVEFAPDICSRVTFVNFTVTRSSLQNQCLNAVLKIERPDIDQKRSDLLKAQGEFQLKLRHLEKDLLQSLNEAQGNLLENDKIIARLETLKREAADVAKKVEETDVVMQEVESVSTEYVPLAQSCSNIYFTLEAMNQIHFLYQYSLQLMLDIFSSVLINNPELANVKAASDRLKIITKNLFQVTYNRLARGMLHEDQITFATILARIFLKGSTPIGFLENEFQHFLRSQEATITSSDSNKQDNLGLTLHQDQIDSVKRLKKLKVFAKIEEKVKSTKDIKNWTLTVTPESNVPELWVDDNNYNDEKLSKIAKGMYNLLIIQAIRPDRLLASTQKFIASVLGDTFTESVRGTLDLASIVEVEVTACVPILLCAVQGYDPSGRVEDLASEQGKQLTGIAIGSAEGFSQAEKAINSAAKTGKWVMLKNVHLATSWLVSLEKKIHSLQAHPNFRLFLTMEITPKLPVNLLRAGRVLVFEPPPGIKANLLRTLSSINNQRMSKEPVERSRLYFLLAWLNAIVQERLRYVPLGYSKKYEFGESDFKCALDTIDTWVDGAAMGRTNLPPEKIPWVALQTLLGSCIYGGKIDNAFDQRLLNSFLGYLFTEKCFDHNFALVSDADDGSNIAFPESTKHTDILQWVHKLPDLQTPSWLGLPNSAEKVLLTNLAARLKKDVLTLVATDEAATEDAKQEKGQSLIGNILKMQQSLEDDEELVVGQSKTKRTIEVGDGRPAWMRQLYQSTQTWLQILPKSVTPLQRTIENIKDPMYRCFEREVNSGCNLLASVRKDLEDVAEVCKGAKKPTNHHRSMMADLAKGIIPKMWIRYAIPPGLTVIQWIQDFADRIKQLLHISDTAAKSGVIALRSIQVWLGGLFMAEAYITATRQSVAQNNKWALEELFLDVELGEGKVDSNTCVITGLRLMGSEIVDPRTLKLSTLIYKDIDICRLKWIRVEKSQQLEGSSAKDKVCLPIYLNAARSTVLFTLYFSTTDSSYDFYKRGVAI 4104
BLAST of Cytoplasmic dynein 1 heavy chain 1 vs. Planmine SMEST
Match: SMESG000064358.1 (SMESG000064358.1) HSP 1 Score: 6914.7 bits (17939), Expect = 0.000e+0 Identity = 3324/4659 (71.35%), Postives = 3935/4659 (84.46%), Query Frame = 3 Query: 87 MADITANLVQPPDQEITAISLPKFIKYLTLYAFPCMLNDDESKSRKDYELFLSEPQNEECLTKFINDNQVTTLTIQQTKRXXXXXXXXXXXXKISNEVNFESNKSQTSIFIKNNQVIEADKTISSQLQVLSYCDGPPFETMHSLVCYGLLPYFXXXXXXXXXXXXXXXXXMVPSVEKKIAELEIGLLHLQQNIEIPEITLTPHPYVAHIIQEKLLQNKEARVSDFEDKFEDTQFLNQLQAGVNRWIKEIQKVTKLNRDPSTGTALQEISFWLNLEHSLDKIQEKRESLEVALTLAILKQAKRFHATTSFDTDTALSSAKIQVKDYNQLMKDFPINDLLSASQLDKISEALQQIFSHLKKVRATKYPVNRIIKLMEALSRDLTTQLMKVISNMHLMSMPYDEFEKIFTACQQVFSTWEDEYDKMQNLLRDIAKKKREEFTKFAWKMNATHKKLQTRLENIKKFRYQHEQLRQVIVRVLKPVTKVVPSVEAGVPKDQITDKGDKSSTFLPESADTSSIDEVNAAYEIVKVIDCLDFAKEENDEWDAAIKRYEERIDRVESRIASHLRDLLGQSKNANEMFRYFSRFNALFVRPHIRGAIGEYQTQLIQRVKDDIEALHNKFKVQYASSTACKMSKVRDLPPVSGSIIWVRQILRQLNAYMKRVEDVLGKDWAQHIEGQKLKADGESFKLKLNTSELFEEWSKKVAEKSLSVAGSIFNVESTRTVVTVRDREPQKITVLKLKVNFLPDVITLAKEVRNMRALGFRTPLSIVNKAHSANQLYPFAISLIESVRTYESTCSKIEEHKMQNISLLTAGLRKDVQLCIHEGVQITWESYRLDQYVQKLAELVFSFQEKVDDLVIVIKEIDFNVKALETCSYNKQTFEEILIRIQEAVDNMSLHQFSNLAQWVSNLDSLVEQRLIVRLEAGLLEWIKVLKGXXXXXXXXXXXXXXXVNSMAKHRLGGKPQIKKLIHELRITNQQMHLYPSIEVATQDILYQMSSWQNIILNLSRIVHSRYQVGLETESDNQKTYKKLLSSLPNSGESLENAYAAVHNILRDANEYVKTWTNYQSLWDLQGDQLFSLIADDNTVWMNVLEEIKSMRKHFDVAETQKEFGPLVIAFGKVQSKVSMKYDNWHKEVLTKFGQNMGKMMTTLYNEVQRARNELEQQSIDSGGTNESVNFITYTQNIKRKMNTWEKQAEACRAGQNILCRDRFQFPNDWLDSENIQGEWSAFKEIMRRKQETISSQVASLQMKITEEDKIVESKTTEVLGNWEKDKPIAGDLTPEEAVNIIQILEGKFNRLKEERENVQKAKEALELTEIGVKPISEEKVTNALSELHDLKNVWNELKSIWEKIRDMKETPWLSVQPRKLRQDIENLTAQLKELPNSFKQYASFEHVRTLLKMYMKVNASIVELKSEAIKERHWRMLMRKLNVSWSLNELQLGKVWDIDLVKNEEIIREVLAIAQGEKALEEYLRQITEVWKNYVLELTNYQSKSKIIKGWDDLFNKVKEHINNVTSMKASPYFKQFEEEATAWEDRLNKINALFDVWIDVQRRWIYLDGIFAGSADIKVLLPVESQRFQSVSTEFLGLMKKVQKSPLVTDVLNIANVQRQLERLADLLGKIQKSLGEYLERQRSSFPRFYFVGDEDLLEIIGNSXXXXXXXXXXXXMFAGVHSIILSEDEKVILGMMSKEGEELRFISPVSIIEHPRINDWLTAMEKEMRVSLAKYLNVAVKEISGWRTESNIDKDKFMVWLDKYQAQIVVLAAQITWSEAVEASLASGVSLESTMTVVHSTLNMLADTVLYEQPPVRRRKLEHLIIEYVHQRDVLRALHNDGVSSNKNFDWMSQMRFYFDPKQTDPLHQLSIHVANAKFHYGFEYLGVCDRLVQTPLTDRCYLTMTQALEARLGGSPFGPAGTGKTESVKSLGNQLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLSAVSQQIQGIQEALRELMVSKKDSINVELLGKQVHVNPDMAIFITMNPGYAGRSNLPDNLKKLFRSLAMTQPDRQLIAQVMLYSQGFRTAEVLAGKVVPFFKLCDEQLSPQSHYDFGLRALKSVLVSAGNVKRDRIKQEKEKIVARGEEINETAIAEQLPEQEILIQSVMETMVPKLIADDIPLLYSLLTDVFPGVEYRQAEMKRLREELRKVSENKFLVYSDEPNTAGYLWVEKVLQLYQITTIHHGLMMVGPSGSGKTMACRVLLQALENIDGIEGVAHIIDPKSISKDSLYGYMDPNTREWTDGLFTHILRRIIDSVRGESNKRQWIVFDGDVDPEWVENLNSVLDDNKLLTLPNGERLAIPPNVRIMFEVQDLKYATLATVSRCGMVWFSEEVLTTGMILTHFLNELKKVQVMEGEEDFSVNQGDTGADADSKISSSPIIQLQTQVSSILAPFFTEDGLIAKCLDYSTTLEHIMDFTRLRALTSLFSMIKQSIRNMIEYNQSHSDFPLNNEQIENYVAKSLISSVVWSMSGDSKLKVREQLSQYIKNISTVDLPTV-GGIKNIIDFEVNIQGTWVAWSNKVPQIEVETHKITATDVVVPTMDTVRHEALLYTWLAEHRPVLLCGPPGSGKTMTLFSALRCLPDMEVVGLNFSSATTPELMLKTFDQYCEYRKTPNGIVLAPQQLNKWLIFFCDEINLPDMDKYGTQRVISFLRQMVEHHGFYRITDMQWVSFERIQFVGACNPPTDPGRKPLSHRFLRHVPVVYVDYPGETSLKQIYSTFNRAMLRMLPSLRGYADTLTNAMVEFFLKTQERFTHDMQPHYIYSPREMTRWVRGIHEALKPLESLSVEGLVRIWAHEALRLFQDRLVEEDERHWTDDNINEVALKHFPNINKEEALKRPILYSNWLSKDYSAVTQEELRDYVKARLKVFYEEELDVPLVLFNQVLDHVLRIDRVFRQPQGHLLLIGVSGAGKTTLSRFVSWINGLSVFQVKVHNKYTAEDFDEDLRNVLRRSGCKGEKITFIMDESNVMDSSFLERMNTLLANGEVPGLFEGDELTTLMTQCKEGAIREGLMIDSQEELYKWFTQQICRNLHVVFTMNPSADGLKDKASTSPALFNRCVLNWFGDWSLEAYFQVGKEFTNRLDLERTDYKVPDTLPCIAEGLLPQNPIYRDVVVNALVFVHQTMHQANVRVQKRGGRTAAITPRHYLDLIAHYMKLSAEKRADLEEQQLHLNNGLKKIEQTVDQVEVMQRSLTKKRQELENMNEAANAKLKQMVQDQQEAEQKKTTGQALKEELAKQEQFVNEKQKTVKQELDQVEPTVNEAKQAVQNIRKKDIQEIKAMKNPPNAVKMAVESICLLLGEKTTDWQSILKVIIKDTFVTSILNFNTDDVSDNTRETMKKKYLSNPDYNFEKVNKASNACGPMVKWVLAQISYADILKRVEPLRNELTELSDAAEQNRKKSQETEDLIAQLEKSIAKYTEEYATLISQAQTIKSDLASVESKVGRSVALLGSLSSERTRWDSGSETFKAQMATINGDCLLSSAFMAYGGYFDQHMRTSLFNTWCHHLSEADILFRSDLARVEYLSNPDDRLRWQANSLPADDLCVENAIILRRYNRYPLIIDPSGQATTFLLNEYKEKKITKTSFLDDSFRKTLESALRFGTPLLVQDVESYDPILNPVLNREVRRTGGRTLITLGDQDIDLSPTFTIFLSTRDPSVEFAPDICSRVTFVNFTVTRSSLQNQCLNAVLKIERPDIDQKRSDLLKAQGEFQLKLRHLEKDLLQSLNEAQGNLLENDKIIARLETLKREAADVAKKVEETDVVMQEVESVSTEYVPLAQSCSNIYFTLEAMNQIHFLYQYSLQLMLDIFSSVLINNPELTNVKAASDRLKIITKNLFQVTYNRLARGMLHEDQITFATILARIFLKGSTPIGFLENEFQHFLRSQEATITSSDSNKQDNLGLTLHQDQIDSVKRLKKLKVFAKIEEKVKSTKDIKNWTLTVTPESNVPELWVDDN--NYN--DEKLSKIAKGMYNLLIIQAIRPDRLLASTQKFIASVLGDTFTESVRGTLDLASIVEVEVTACVPILLCAVQGYDPSGRVEDLASEQGKQLTGIAIGSAEGFSQAEKAINSAAKTGKWVMLKNVHLATSWLVSLEKKIHSLQAHPNFRLFLTMEITPKLPVNLLRAGRVLVFEPPPGIKANLLRTLSSINNQRMSKEPVERSRLYFLLAWLNAIVQERLRYVPLGYSKKYEFGESDFKCALDTIDTWVDGAAMGRTNLPPEKIPWVALQTLLGSCIYGGKIDNAFDQRLLNSFLGYLFTEKCFDHNFALVSDADDGSNIAFPESTKHTDILQWVHKLPDLQTPSWLGLPNSAEKVLLTNLGQSLIGNILKMQQSLEDDEELVVGQSKTKRTIEVGDGRPAWMRQLYQSTQTWLQILPKSVTPLQRTIENIKDPMYRCFEREVNSGCNLLASVRKDLEDVAEVCKGAKKPTNHHRSMMADLAKGIIPKMWIRYAIPPGLTVIQWIQDFADRIKQLLHISDTAAKSGVIALRSIQVWLGGLFMAEAYITATRQSVAQNNKWALEELFLDVELGEGKVDSNTCVITGLRLMGSEIVDPRTLKLSTLIYKDIDICRLKWIRVEKSQQLEGSSAKDKVCLPIYLNAARSTVLFTLYFSTTDSSYDFYKRGVAI 14048 M++ VQ P +E I++ FIKYLTLY F CMLND E+K R++YELFLSEP+N+E L KFI+D Q++TLTIQ KREE++ S+ +F F++SNE+ + NKSQT IFIK Q+IEA K ISSQ+Q+++Y G PFE+MH+LV +GLLP++KSYIK I KD+ + ++KM +VE+++ +LEIGLL+L+QN EIPEI LT HPYV +IQEK +N+ RVSDF+DKFED+QFLNQLQ+GV RWIKEIQKVTKL+RD S+GT LQEI+FWLN E SL +IQEKRESLEV+LTL ILKQAKRFHAT SFDTDTAL A ++YNQLMKDFPIN+LLSA+ L++I+EAL+ IFSHLKK+ T+YPVN+ I+LMEALSRDLTTQ+M+VI ++LM MP+ EF I CQ+VF TWE+E+DK+Q+ LR++A+K+ E F KFAWKMNATHKKLQ RLENIK+FR +HEQLR+V++RVLK TK P E Q +D+ K LP+ D SSI++++ AYEIV ID LDFA E EWDAA++RYEE+IDR+ES+IAS+LRDLLG+SKNANEMFRYFSRFNAL VRPHIRGA+GEYQ+QLIQR+K+DIE+L KFK Y + T +MS +R+ PPVSG+IIW+RQI QLN YM+RVE VLGKDW +HIEGQ+LK GE+FK+KLN LF+ W + V+ KSLSV+GS+FNVE + + ++D K + LKLKVNF P++ITL+KEVRNMR LGF P S+V+KA++A +LYP AISLI++++TYE KI+EHKMQN+S+LT+GL +VQ I++G++ TW+ +LD YVQ AE VFSFQ+KV+DL+ + EI FNV ALETC+Y+ ++F+E+++ IQ+ VDN++ HQF+NL+ WV L+ +E +L +RLEAGL++W L+G +E D++ +S+ + ++GG P+IK +I EL+ITN+++ L PSIE AT+++L ++SSWQ +IL+L RIVHSRYQVGL+ S +TYK L S L SG+S++ AYAA+ ++DA E++K W NYQSLWDLQ DQLFS I+D+ VW+NVL EIK +RK+FDVAETQK GPL+I FGKV+SKVS+KYD+WH+EV TKFG ++GKMM+TLY+++++ARNELE QS+D G T + VNFI YTQNI RK+N WEKQ E CR GQN+L RDRF+FP++W+DS+NI+GEW+AFK+I++RKQE IS ++ASLQMK+ EEDKI+E KT+E+L WEK+KPIAG+L P+EAV II LE K +L EEREN+QKAKEALELTE G KP SE K+ NA SEL DLK VW+ELK IWEKI +MKE W+SVQPRKLRQDI+NL Q+K LPNSF QYAS H+R+LL+ Y+K N+SIVELKSEA+KERHWRM+MRKL+V+WSLNELQLG +WDI VK E IIREVLAI+QGE+A+EEYLRQI+E+WK++ LELTNYQ+K+ IIKGWDDLFNK+KEH+NNVT MKASPYFK+FEEE+ +WEDRLNK+N++FDVWIDVQRRWIYLDGIF GSADIKVLLP+ESQRFQ+VSTE LGLM+KVQ SPLVTDVLNI N+Q+QL RLADLLGKIQKSLGEYLERQR+SFPRFYF+GDEDLLE+IGNSK+L KLQKHFKK+F GVHSIIL E+EKVILGM+SKEGEELRF++P+ I E+ RINDWLTA+EKEMR SLAKYL +AVKEI+ W+ ES D+DKFMVWLDKYQAQIV LA QITW+E+VE S ASG SLE ++ +VH+ LNMLAD VL EQP +RR+K+EHLIIE+VHQRDVLR LH GV +N NF W+SQMRFYFD KQ +PL QLSIH+ANAKF+YGFEYLG+ DRLVQTPLTDRCYLTMTQALEARLGGSPFGPAGTGKTESVKSLG+QLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLSAVSQQIQ IQEALR+ M+SKK+ ++VELLGK V+VNPDMAIFITMNPGYAGRSNLPDNLKKLFRSLAMTQPDRQLIAQVMLYSQGF+ AE L+ KVVPFFKLC+EQLSPQ HYDFGLRALKSVL S+GN KR++IK + ++A+ EE NET + +L EQEILIQS+METM PKLIADDIPLL SLL+DVFPGV Y+ A M +LREE+RKVS NK LV S+ N GYLW EKVLQLYQI IHHGLMMVGPSGSGKTMAC+VLL+ALEN+DGI+GVAHIIDPKSISK+SLYG MDPNTREWTDGLFTHILR+IID+VRGE NKRQWI+FDGDVDPEWVENLNSVLDDNKLLTLPNGERL IP NVRIMFEVQDLKYATLATVSRCGMVWFSEEVLTT MILTHFLN+L + E +E + +N + + + KIS + L QV SIL P+F +GLI KCL+YS+ LEHIMDFTRLRALTSLFSMIK+ I+N+IEYNQ+H DFPL EQ+ENY+ KSL SS+VWSM+GDSKLK+REQLS YIK S +D V G IKN IDFEV+IQG WV S +VP+IE+E KI ATD+VVPT+DTVRHE LLYTWLAEHRPV+LCGPPGSGKTMTLFSALR LPDMEVVGLNFSSATTPELMLKTFDQYCEYRKTPNG VL PQQ+NKWLIFFCDEINLPDMDKYGTQR+ISFLRQM+E+HGFYRI+DMQW+S ERIQFVGACNPPTDPGRKPLS RFLRHVP++YVDYPGE SLKQIYSTFNRAMLR+LP L GY+DTLT+AMVEFFLKTQERFT D+QPHYIYSPREMTRWVRGI+E LK LES S+E LVRIWAHEALRLFQDRLV+++ER+WTDD I+E+A+K+FP +NK E LKRPILYSNWL+++YS V QEELR +VKARLKVFYEEELDVPLVLFNQVLDHVLRIDRVFRQ QGH+LLIGVSGAGKTTLSRFV+WING VFQVKVH KY+A++FD+DLR VLRRSGCKGEKI FIMDESNV DSSFLERMNTLLANGEVPGLFEGDE TLMTQCKEGA+ EGL+ID+ EELYKWFTQQICRNLHV+FTMNPS DGLK+KA TSPALFNRCVLNWFGDWSLEAYFQVGKEFT+ LDLE++ + P TL + E LLP P Y+DVVVN+LVFVH TMHQ N++V + G+ AITPRH+LDLIA ++KLS EKR DLEEQQLHL NGLKKIEQTV ++E MQ+SLT KR+ELENMNEAAN KLKQMVQDQQEAEQKK+T LK+EL +QE +VNEKQK V+ ELDQVEP V+EAKQAVQNIRKKDI EI+AMKNPPNAVK+AVESICLLLGEKT+DWQSILKVII+D FV ++LNFNTD ++D R+T+ +KY+SNPD+ FEKVNKASNACGPMVKWVLAQISYA IL+RVEPLRNEL EL+++A+ N +K +ETE++I +LE+ I KYTEEYA LISQ Q IKSDL+ VE KV RS+ALL SL +ER+RWD+ SE+FK+QM INGDCLLSSAF+ YGGYFDQ MRT+LF+TWCH+L +A IL+RSDL+ EYLS PDDRLRWQ N LP D+LCVENAIIL R+NRYPLIIDPS QA T+L+NEY K I KTSFLDDSFRKTLES+LRFGTPLLVQDVESYDPILNP+LN+E+RRTGGRTLITLGDQD+DLSPTF IFLSTRDPSVEF+ DICSRVTFVNFTVTRSSLQ QCLNAVLK+ERPDI+QKR DL+K QGEF L+LRHLEKDLLQSLNE+QGNLLEND II RLETLK EAA VAKKVEETDV+MQEVE+VS EY+PLA S SNIYFTL+++NQIH+LYQYSLQ MLDIFS VL +PEL N + S+RLK+ITK LFQ+TYNR+ARG+LH DQITFA ILARI+LKG P GFLE+EFQHF+ QE I S+ + G+ Q QI+S+ RL+KLK F I K KS K I+NW +V PE+NVPE+W D N NYN +E L+ I K M LL++QAIRPDRL+ S Q FI+SV G++F SVR TL+L +IV+ E T+ +PILLCAVQGYDPS +VEDLA E+GKQL+ IAIGS EGFSQAEKAIN+A K+G WV+ KNVHL+ SWL SL KKI+SL AH NFRLFL+MEI PKLPVNLLR GR+LVFEPPPGIKANLLRT S+I +RMSK+P+ERSRLYF+LAW NA+VQERLRYVPLGYSKKYEF ESDFKC LDT+D WVD AM RTNLP E+IPW ALQTLLGSCIYGGKIDN FDQ+LL SFL YLF+E F F+L+S+ + I FPE TK++DI+QW+H LPD QTPSW+ LPNSAEKVLL NLG SLIGNILK+ QSLE+DEE++V Q+K+++ I G+G+P WM+QL+Q+TQ WL +LP+S+ PL+RT +NIKDP+YRCFERE+ GC LL VR+DLED+AE+C KKPTNHHRS+MADL IIPK WI+Y +P LTVIQWI DF R+ QL+HIS+ A G+ + +I+VWLGGLFM EAYITA RQSVAQ+NKW LEELFLDVELGEG+++ NT VITGL+LMG E VD +TLKLSTLI+ D+DIC LKWIR+ K+ + ++KVCLP+YLNAARST+LFTLYF T+DSSY F K GVAI Sbjct: 1 MSESLTEFVQFPRKEKEVINIKDFIKYLTLYTFNCMLNDAENKERENYELFLSEPENKEYLYKFISDPQISTLTIQHIKREEDDESDADFYFQLSNEIVLDLNKSQTLIFIKTTQIIEAAKLISSQIQIVNYSSGSPFESMHALVHHGLLPFYKSYIKMISKDNKTLNEKMTTNVERRMIDLEIGLLNLKQNTEIPEIILTTHPYVLKVIQEKASENQIGRVSDFKDKFEDSQFLNQLQSGVMRWIKEIQKVTKLHRDSSSGTTLQEITFWLNFEQSLIRIQEKRESLEVSLTLGILKQAKRFHATKSFDTDTALCDALNTARNYNQLMKDFPINNLLSANNLEEINEALKTIFSHLKKITMTEYPVNKTIELMEALSRDLTTQMMEVIGTINLMDMPFYEFGSIINNCQKVFITWENEFDKIQSFLREMARKRWEGFGKFAWKMNATHKKLQIRLENIKRFRDEHEQLRKVVIRVLKLTTKTDPVNE------QFSDE-QKVIVALPKEIDRSSINQIDVAYEIVNSIDYLDFAIGETSEWDAAVRRYEEKIDRIESQIASNLRDLLGKSKNANEMFRYFSRFNALLVRPHIRGAVGEYQSQLIQRIKEDIESLQTKFKTHYTNGTVYRMSTIRNFPPVSGTIIWIRQIRNQLNNYMRRVESVLGKDWDKHIEGQRLKVVGETFKVKLNVDALFKLWLESVSLKSLSVSGSVFNVE-IKFLSAIQDNSASKKSFLKLKVNFNPEIITLSKEVRNMRDLGFPVPFSLVSKANTAKELYPLAISLIDNIKTYELVLRKIDEHKMQNLSILTSGLHFEVQRFINKGIKATWKHKKLDIYVQTFAERVFSFQDKVEDLIQTVTEIYFNVYALETCTYSTKSFQELILNIQKGVDNINFHQFTNLSHWVLLLEDTIETKLAMRLEAGLIKWTLALRGNFQEINIKDKN----ADSVIQDKMGGSPEIKDIILELKITNRKLELIPSIEHATRELLERLSSWQAVILDLPRIVHSRYQVGLQINSAKNETYKDLQSKLGRSGQSMDEAYAAIFQTIKDAEEFIKQWKNYQSLWDLQSDQLFSQISDNLIVWINVLNEIKKLRKNFDVAETQKRIGPLLIVFGKVRSKVSIKYDSWHREVSTKFGSSLGKMMSTLYSDMRQARNELENQSLDLGSTIDCVNFIIYTQNILRKVNQWEKQNEICRDGQNLLFRDRFEFPSNWIDSDNIKGEWNAFKDIIKRKQEMISVRIASLQMKVVEEDKIIELKTSEMLNIWEKEKPIAGELIPKEAVKIINSLESKILQLLEERENIQKAKEALELTEHGTKPYSEGKIMNAYSELIDLKKVWSELKLIWEKIEEMKELLWISVQPRKLRQDIDNLLVQMKHLPNSFSQYASHVHIRSLLQFYLKANSSIVELKSEAVKERHWRMIMRKLDVNWSLNELQLGNIWDIVSVKYEGIIREVLAISQGERAIEEYLRQISEIWKDFALELTNYQNKTMIIKGWDDLFNKIKEHVNNVTGMKASPYFKEFEEESNSWEDRLNKMNSVFDVWIDVQRRWIYLDGIFTGSADIKVLLPMESQRFQNVSTEILGLMRKVQSSPLVTDVLNIPNIQKQLMRLADLLGKIQKSLGEYLERQRASFPRFYFIGDEDLLEVIGNSKELHKLQKHFKKLFTGVHSIILCENEKVILGMVSKEGEELRFLTPIPITENVRINDWLTALEKEMRNSLAKYLAIAVKEIATWKIESECDRDKFMVWLDKYQAQIVNLAVQITWTESVEESFASGKSLEVSINIVHNILNMLADLVLNEQPHIRRQKIEHLIIEFVHQRDVLRKLHQMGVDNNNNFHWLSQMRFYFDRKQRNPLQQLSIHIANAKFNYGFEYLGIYDRLVQTPLTDRCYLTMTQALEARLGGSPFGPAGTGKTESVKSLGHQLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLSAVSQQIQEIQEALRDPMISKKEVVSVELLGKNVYVNPDMAIFITMNPGYAGRSNLPDNLKKLFRSLAMTQPDRQLIAQVMLYSQGFQQAETLSRKVVPFFKLCEEQLSPQPHYDFGLRALKSVLTSSGNAKREKIKVIQSTMLAKAEETNETFVTNELVEQEILIQSIMETMAPKLIADDIPLLDSLLSDVFPGVHYKSAPMIKLREEIRKVSINKHLVCSNMANYQGYLWTEKVLQLYQIINIHHGLMMVGPSGSGKTMACKVLLEALENVDGIKGVAHIIDPKSISKESLYGSMDPNTREWTDGLFTHILRKIIDNVRGEGNKRQWIIFDGDVDPEWVENLNSVLDDNKLLTLPNGERLEIPSNVRIMFEVQDLKYATLATVSRCGMVWFSEEVLTTEMILTHFLNKLTHGHLTEEDEMYVLNTKHSIGN-NPKISKTTHDDLLNQVVSILTPYFARNGLIVKCLEYSSNLEHIMDFTRLRALTSLFSMIKRCIQNVIEYNQTHLDFPLEKEQVENYITKSLFSSIVWSMTGDSKLKIREQLSLYIKESSLIDASNVIGSIKNTIDFEVSIQGLWVPLSTRVPRIEIEAQKIIATDIVVPTVDTVRHETLLYTWLAEHRPVVLCGPPGSGKTMTLFSALRRLPDMEVVGLNFSSATTPELMLKTFDQYCEYRKTPNGTVLVPQQINKWLIFFCDEINLPDMDKYGTQRIISFLRQMIEYHGFYRISDMQWISLERIQFVGACNPPTDPGRKPLSQRFLRHVPIIYVDYPGEDSLKQIYSTFNRAMLRILPQLIGYSDTLTDAMVEFFLKTQERFTQDVQPHYIYSPREMTRWVRGIYEVLKSLESPSLEDLVRIWAHEALRLFQDRLVKDEERNWTDDTIDEIAVKYFPTLNKYETLKRPILYSNWLNRNYSPVNQEELRKFVKARLKVFYEEELDVPLVLFNQVLDHVLRIDRVFRQSQGHVLLIGVSGAGKTTLSRFVAWINGFKVFQVKVHKKYSAQNFDDDLRTVLRRSGCKGEKIAFIMDESNVKDSSFLERMNTLLANGEVPGLFEGDEYMTLMTQCKEGALHEGLLIDTNEELYKWFTQQICRNLHVIFTMNPSVDGLKNKACTSPALFNRCVLNWFGDWSLEAYFQVGKEFTDNLDLEKSGFVCPKTLSFVTEALLPPIPKYQDVVVNSLVFVHLTMHQVNLKVYNKDGKAVAITPRHFLDLIAQFIKLSGEKRTDLEEQQLHLKNGLKKIEQTVQEIESMQKSLTIKRRELENMNEAANMKLKQMVQDQQEAEQKKSTSHMLKKELTEQELYVNEKQKAVRLELDQVEPIVSEAKQAVQNIRKKDIHEIRAMKNPPNAVKLAVESICLLLGEKTSDWQSILKVIIRDNFVQNVLNFNTDGITDGIRDTL-EKYVSNPDFTFEKVNKASNACGPMVKWVLAQISYAGILRRVEPLRNELKELTNSAKLNMEKLKETENIILELEEKIRKYTEEYAVLISQGQIIKSDLSIVEKKVNRSIALLHSLGAERSRWDNASESFKSQMEMINGDCLLSSAFITYGGYFDQQMRTNLFSTWCHNLLQAGILYRSDLSYTEYLSIPDDRLRWQTNGLPDDNLCVENAIILSRFNRYPLIIDPSDQAITYLMNEYSGKTIAKTSFLDDSFRKTLESSLRFGTPLLVQDVESYDPILNPILNKEIRRTGGRTLITLGDQDVDLSPTFKIFLSTRDPSVEFSSDICSRVTFVNFTVTRSSLQTQCLNAVLKVERPDINQKRLDLMKIQGEFHLRLRHLEKDLLQSLNESQGNLLENDIIITRLETLKLEAAQVAKKVEETDVIMQEVENVSGEYMPLALSFSNIYFTLQSLNQIHYLYQYSLQFMLDIFSFVLTKSPELNNSQLPSERLKLITKGLFQITYNRVARGVLHSDQITFAMILARIYLKGIAPDGFLESEFQHFIERQETAIPGSNQYDTVDYGVDFDQQQINSLGRLRKLKTFKNIGGKCKSLKYIQNWITSVNPETNVPEVW-DSNIPNYNNDNENLTDIVKSMNKLLLVQAIRPDRLVNSVQNFISSVFGESFYGSVRKTLNLENIVKCETTSSIPILLCAVQGYDPSSQVEDLALEEGKQLSSIAIGSVEGFSQAEKAINAAIKSGGWVLFKNVHLSISWLTSLVKKIYSLSAHSNFRLFLSMEIMPKLPVNLLRIGRILVFEPPPGIKANLLRTFSAIPEKRMSKDPIERSRLYFMLAWFNAVVQERLRYVPLGYSKKYEFNESDFKCGLDTVDKWVDATAMDRTNLPAERIPWNALQTLLGSCIYGGKIDNVFDQKLLESFLKYLFSEISFRPEFSLISEINGKLQITFPEFTKYSDIIQWIHNLPDSQTPSWIELPNSAEKVLLINLGNSLIGNILKLHQSLENDEEIMVDQNKSQQKIRHGNGQPTWMQQLFQTTQEWLHLLPRSIVPLRRTTDNIKDPIYRCFEREIILGCKLLVEVRQDLEDIAEICNALKKPTNHHRSLMADLGGRIIPKSWIKYNVPSKLTVIQWINDFLKRVNQLIHISNIAINQGIQSFPTIKVWLGGLFMPEAYITAIRQSVAQSNKWPLEELFLDVELGEGEINVNTFVITGLKLMGCEKVDSKTLKLSTLIHTDLDICLLKWIRM-KNDVTQEKYIENKVCLPVYLNAARSTILFTLYFHTSDSSYRFCKNGVAI 4643
BLAST of Cytoplasmic dynein 1 heavy chain 1 vs. Planmine SMEST
Match: SMESG000051829.1 (SMESG000051829.1) HSP 1 Score: 1416.75 bits (3666), Expect = 0.000e+0 Identity = 981/3376 (29.06%), Postives = 1692/3376 (50.12%), Query Frame = 3 Query: 3999 QKAKEALELTEIGVKPISEEKVTNALSELHDLKNVWNELKSIWEKIRD-MKETPWLSVQPRKLRQDIENLTAQLKELPNSFKQYASFEHVRTLLKMYMKVNASIVELKSEAIKERHWRMLMRKLNVSWSLNE--LQLGKVWDIDLVKNEEIIREVLAIAQGEKALEEYLRQITEVWKNYVLELTNY----QSKSKIIKGWDDLFNKVKEHINNVTSMKASPYFKQFEEEATAWEDRLNKINALFDVWIDVQRRWIYLDGIFAGSADIKVLLPVESQRFQSVSTEFLGLMKKVQKSPLVTDVLNIANVQRQLERLADLLGKIQKSLGEYLERQRSSFPRFYFVGDEDLLEIIGNSXXXXXXXXXXXXMFAGVHSIILSED---EKVILGMMSKEGEELRFISPVSIIEHPRINDWLTAMEKEMRVSLAKYLNVAVKEISGWRTESNIDKDKFMVWLDKYQAQIVVLAAQITWSEAVEASL-----ASGVSLESTMTVVHSTLNMLADTVLYEQPPVRRRKLEHLIIEYVHQRDVLRALHNDGVSSNKNFDWMSQMRFYFDPKQTDPLHQLSIHVANAKFHYGFEYLGVCDRLVQTPLTDRCYLTMTQALEARLGGSPFGPAGTGKTESVKSLGNQLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLSAVSQQIQGIQEALRELMVSKKDSINVELLGKQVHVNPDMAIFITMNPGYAGRSNLPDNLKKLFRSLAMTQPDRQLIAQVMLYSQGFRTAEVLAGKVVPFFKLCDEQLSPQSHYDFGLRALKSVLVSAGNVKRDRIKQEKEKIVARGEEINETAIAEQLPEQEILIQSVMETMVPKLIADDIPLLYSLLTDVFPGVEYRQAEMKRLREELRK-VSENKFLVYSDEPNTAGYLWVEKVLQLYQITTIHHGLMMVGPSGSGKTMACRVLLQALENIDGIEGVAHIIDPKSISKDSLYGYMDPNTREWTDGLFTHILRRIIDSVRGESNKRQWIVFDGDVDPEWVENLNSVLDDNKLLTLPNGERLAIPPNVRIMFEVQDLKYATLATVSRCGMVWFSEEVLTTGMILTHFLNELKKVQVMEGEEDFSVNQGDTGADADSKISSSPIIQLQTQVSSILAPFFTEDGLIAKCLDYSTT--LEHIMDFTRLRALTSLFSMIKQSIRNMIEYNQSHSDFPLNNEQI-ENYVAKSLISSVVWSMSG----DSKLKVREQLSQYIKNISTV------DLPTVGG-----IKNIIDF---EVNIQGTWVAWSNKVPQIEVETHKITATDVVVPTMDTVRHEALLYTWLAEHRPVLLCGPPGSGKTMTLFSALRCL-PDMEV-VGLNFSSATTPELMLKTFDQYCEYRKTPNGIVLAPQQLNKWLIFFCDEINLPDMDKYGTQRVISFLRQMVEHHGFY-RITDMQWVSFERIQFVGACNPPTDPGRKPLSHRFLRHVPVVYVDYPGETSLKQIYST--------FNRAMLRMLPSLRGYADTLTNAMVEFFLKTQERFTHDMQPHYIYSPREMTRWVRGIHEALKPLESLSVEGLVRIWAHEALRLFQDRLVEEDERHWTDDNINEVALKHFPNINKEEALKRPILYSNWLSKDYSAVTQ--EELRDYVKAR------LKVFYEEELDVPLVLFNQVLDHVLRIDRVFRQPQGHLLLIGVSGAGKTTLSRFVSWINGLSVFQVKVHNKYTAEDFDEDLRNVLRRSGCKGEKITFIMDESNVMDSSFLERMNTLLANGEVPGLFEGDELTTLMTQCKEGAIREGLMIDSQEELYKWFTQQICRNLHVVFTMNPSADGLKDKASTSPALFNRCVLNWFGDWSLEAYFQVGKEFTNRLDLERTDYKVPDTLPCIAEGLLPQNPIYRDVVVNALVFVHQTMHQANVRVQKRGGRTAAITPRHYLDLIAHYMKLSAEKRADLEEQQLHLNNGLKKIEQTVDQVEVMQRSLTKKRQELENMNEAANAKLKQMVQDQQEAEQKKTTGQALKEELAKQEQFVNEKQKTVKQELDQVEPTVNEAKQAVQNIRKKDIQEIKAMKNPPNAVKMAVESICLLLGEKTTDWQSILKVIIKDTFVTSILNFNTDDV----SDNTRETMKKKYLSNPDYNFEKVNKASNACGPMVKWVLAQISYADILKRVEPLRNELTELSDAAEQNRKKSQETEDLIAQLEKSIAKYTEEYATLISQAQTIKSDLASVESKVGRSVALLGSLSSERTRWDSGSETFKAQMATINGDCLLSSAFMAYGGYFDQHMRTSL-FNTWCHHLSEADILFRSDLARVE-YLSNPDDRLRWQANSLPADDLCVENAIILRRYNRYPLIIDPSGQATTFLLNEYKEKKITKTSFLDDSFRKTLESALRFGTPLLVQDVESY-DPILNPVLNREVRRTGGRTLITLGDQDIDLSPTFTIFLSTRDPSVEFAPDICSRVTFVNFTVTRSSLQNQCLNAVLKIERPDIDQKRSDLLKAQGEFQLKLRHLEKDLLQSLNEAQGNLLENDKIIARLETLKREAADVAKKVEETDVVMQEVESVSTEYVPLAQSCSNIYFTLEAMNQIHFLYQYSLQLMLDIFSSVLINN-PELTNVKAASDRLKIITKNL-----------------FQVTYN-RLARGMLHEDQITFATILARIFLKGSTPIGFLENEFQHFLRSQEATITSSDSNKQDNLGLTLHQDQIDSVKRLKKLKVFAKIEEKVKSTKDIKNWTLTVTPESNVPELWVDDNNYNDEKLSKIAKGMYNLLIIQAIRPDRLLASTQKFIASVLGDTFTESVRGTLDLASIVEVEVTACVPILLCAVQGYDPSGRVEDLASEQG---KQLTGIAIGSAEGFSQAEKAINSAAKTGKWVMLKNVHLATSWLVSLEKKIHSL-QAHPNFRLFLTMEITPKLPVNLLRAGRVLVFEPPPGIKANLLRT-----LSSINNQRMSKEPVERSRLYFLLAWLNAIVQERLRYVPLGYSKKYEFGESDFKCALDTIDTWVDGAAMGRTNLPPEKIPWVALQTLLGSCIYGGKIDNAFDQRLLNSFLGYLFTEKCFDHNFALVSDADDGSNIAFPESTKHTDILQWVHKLPDLQTPSWLGLPNSAEKVLLTNLGQSLIGNILKMQQSLEDDEELVVGQSKTKRTI--EVGDGRPAWMRQLYQ----STQTWLQILPKSVTPLQRTIENIKDPMYRCFEREVNSGCNLLASVRKDLEDVAEVCKGAKKPTNHHRSMMADLAKGIIPKMWIRYAIPPGLTVIQWIQDFADRIKQLLHISDTAAKSGVIALRSIQVWLGGLFMAEAYITATRQSVAQNNKWALEELFLDVELGEGKVDSNT-------CVITGLRLMGS 13814 Q+ A +L + + P E + N E+ +L ++ EL +K R+ ET W ++ + L + IE + +++P K + ++ LK + +LK EA++ERHW+ LM K ++ +N L V+ ++L + +++I E++ A E ++E+ +R++ E W + Y + + I+ D++ + ++ N+ SM AS + F WE L+ I+ + DVW+ VQR+W+YL+GIF G DI+ LP E+++F ++ F +M + K P++ + N L L+D L K QKSL +YL+ +R++FPRF+F+ D++LL I+G+S + K MF + S+ ++ E M+S E E + F SPV I R+ DW+T +E EMR + V KE + ES + + W+ YQ + + QI W+ VE +L+ ++H+ ++ + V R KL ++I VH RD++ + D + K F+W SQ+RFY+ ++ D ++ I +F YG+EY+G+ RLV TPLTDR YLT+TQAL LGG+P GPAGTGKTE+ K L LG +V NC E D++++G+IF GLCQ GAWGCFDEFNR+E +LS +S Q++ IQ L + K + E G+++ ++ + IFITMNPGYAGR+ LP+++K FR + + PD Q I ++ML+SQGF +A+VLA K+ ++L EQLS Q+HYDFGLRALKSVLV AG ++R+ L E ++L++++ + +PK I +D PL L+ D+FPG++ + + + + ++E+K++V SD+ +K++QLY+ H M+VGP+G GK++ ++L + + + ++PK S LYG +DPNTR+WTDGL ++I R I + + N+R++++FDGDVD WVEN+NSV+DDNKLLTL NGER+ + + ++FEV DL+YA+ ATVSRCGMV+ + L +LN+ E F + DT A K + P T D +I ++ L+ I+ T L +T L +M+ D L E + ++ + I S+ WS+ G DS++K Q+IK++ + D P G + D+ + + W+ W+N VPQ V + ++++VPT+DTVR LL + RPVLL G G+ KT + LR PD + + +NFSS TT + + + E R + P + K L+ F D++N+P +D+YGTQ+ I+ L+ M+E G Y R D+ W + I F+ A P GR + RF+ V +P ++SL IYS+ F+ + +P + T+ N ++ T +F HYI++ R+++R +G+ + + S + R+W HE R+ DRL+ +D++ + I E L +K+ A+ PIL+ ++ + A + E++ +Y A+ ++ + E + LVLF+ LDH+ RI R R GH LL+GV G+GK +L++ ++ +F++ + Y+ +D E+L+ + + G + + F+ + +V++ FLE +N +L++G VP LF DE +++Q + A G M S+E ++++F + NLH+V M+P + L+ + P + N ++WF W +A + V F P+ L+P + R +V V VH ++ + + ++ R +TP++YLD I Y+KL +K E Q L GL+K+ + Q+ + L ++ + A LK++ Q A +KK Q + + Q + + +++ + L + P + +A+ A+ ++ K D+ EI++ PP V++ E I + K +W+ ++ +F+ S+ + D++ S+ R+++ K ++ +++ S A ++K+V A + Y D+ + ++P R ++ L QN+++ ++ ++ I +LE + + Y I + Q ++ + ++ ++ + L+ LSSE RW + K Q + GDCL+ SAF++Y G F R + ++ W + E I SD R+E L+N + +W + LP D+L ++N I+ R +R+PL IDP QA +++ + + + +F D F K LE A+++G P L +DV+ Y DP+++ VL + ++ GR + LGD+++D P F ++L+T+ + ++ P+I + +N+TVT L++Q L+ ++K ER +++++R L++ + + L+ LE LL+ L + GN+L+N ++I LE K +A++V++K++ +E++ Y A+ + ++F L M+ I+ +YQYSL LD+F L + P+ K + + +T+N+ FQ+T + +G L +D++ F F+KG+T I + ++ + SD + QD LT + +K +E+ + K W TPE+ L D +N KL K L +++ R DR+ + ++ +G+ + L+ I + + T PI+ G DP+ V LA G +L I++G + + A+ +++A G W++L+N HL WL LEK + L + HP+FRL+LT E T P+ +L+ +V EPP G+K NL T LSS+NN + P L F LA+ +A+VQER +Y +G++ Y+F ESDF+ + + T++ AA + KIPW +L+ L+G +YGG+ + FD+R+L +++ F + FD A + P+ D L+++ LP TP GL ++AE T+ + + ++ +Q G S+++ I E G + + +L+ + L I P V LQ E+ L+ + K L + G + + L G IP++W R A ++ WI F DR Q + + +WL GL + E+Y+TA Q+ + N W L++ L + + + C + GL L G+ Sbjct: 1387 QELNAAEQLFNLPITPYPE--LFNVQKEMKNLDQIY-ELYDAQKKARENWAETLWKNLDIKVLDEGIEGFLKEWRKMPREVKAMVTARNLAEKLKEFKDALPLFSDLKHEALRERHWKELMTKTGQNFDINPDTFTLSSVFAMELNRFQDVIAEIVTSASKELSIEKGVREVEETWMTLKFSVQPYLKGGKERGYILGALDEVLQILDDNAMNLQSMSASRFIGPFLVSVQNWEKNLSLISEVLDVWMVVQRKWMYLEGIFIG-GDIRSQLPEEAKKFDAIDKTFKKIMTETAKQPIIKQACQVPNRLSDLTNLSDGLEKCQKSLNDYLDSKRNAFPRFFFISDDELLSILGSSDCECVQEHMIK-MFDNISSLRFTKGTSLEMSATAMISSEQEIMEFRSPVLI--EGRVEDWMTKIEMEMR----RTNRVITKEAVFFYRESKVR----VQWMFDYQGMVALCTNQIWWTWEVEDVFRKIKKGQKTALKDYAKLLHNQIDEIVFNVRSPLSKNDRSKLTTVLIIDVHARDIVDSFVRDSIMDAKEFEWESQLRFYW-LREAD---EIQIQQCTGQFGYGYEYMGLNGRLVITPLTDRIYLTLTQALSMYLGGAPAGPAGTGKTETTKDLAKALGLLCVVTNCGEGMDYRSVGKIFNGLCQCGAWGCFDEFNRIEVSVLSVISTQLKTIQNGL----IMKLSRFHFE--GQEIKLDSRVGIFITMNPGYAGRTELPESVKAQFRPVVVIVPDLQQICEIMLFSQGFLSAKVLAKKMTTLYRLSKEQLSKQNHYDFGLRALKSVLVMAGELRRN---------------------DPDLSEDKVLMRALRDMNLPKFIFEDAPLFLGLIQDLFPGLDCPRVRYPDFNDSVEECLAEHKYIVLSDQ--------ADKIVQLYETMKTRHTTMVVGPTGGGKSVVIKILCASQTKLQ-LHTKLIPMNPKDRSVIELYGILDPNTRDWTDGLLSNIFREI--NKPTDKNERRYMLFDGDVDALWVENMNSVMDDNKLLTLANGERIRLQNHCALLFEVGDLQYASPATVSRCGMVYVDPKNLGYNPFWQCWLNK--------KENKF---ENDTLAGLYKKY---------------IPP--TIDRVIEGMMNGQAVEKLKTIIPLTNLNLVTQLCNML---------------DCQLTREGMNQDTIEAIFIQSIYWSLGGCLIEDSQVK----FDQFIKSLCAMPQSNEEDKPAKAGELPSRFPTLFDYYFDSIEEKQEWIPWANLVPQY-VHNPEKKFSEILVPTIDTVRLTWLLTEQIKIQRPVLLVGETGTSKTAVSQTFLRNTDPDKYIQLAINFSSRTTSLDIQRNLESNVEKRTKDS---YGPP-MGKRLLVFIDDMNMPQVDQYGTQQPIAMLKLMLERRGCYDRGKDLNWKKMQDIGFLAAMGKPGG-GRNDVDPRFISLFSVFNATFPSKSSLFSIYSSILSGHCQMFSDEIKNTVPIITKMTMTIYNQIIVQLPPTPSKF------HYIFNLRDLSRIYQGMCQTTLDRFTKS-DQFYRVWRHEFTRVIMDRLINDDDKTFVQKAIEE-QLSENAKSDKDYAMTDPILFGDYRNALEVAEVRLYEDMINYEAAKGLFQEIMEEYSEAVSPMKLVLFDDALDHLTRIHRTIRMDGGHALLVGVGGSGKQSLTKLAAYTGSCDIFEIALSRGYSEKDLRENLKTLYNKLGIENKSTVFMFGDQHVVEEGFLELINNMLSSGIVPALFPDDEREAIISQVRNEASSAG-MGPSKESIWQYFVNKCASNLHIVLCMSPVGETLRTRCRNFPGVVNNTTIDWFFPWPEQALYAVASVFIG-----------PEN------SLIPDDQ--RIEIVKHFVMVHLSVEEYSKEFMQKFRRGNYVTPKNYLDFINTYLKLLEDKDKFTESQCDRLQGGLQKLAEASVQLAELNDKLAIQKVAVTEKTIACENLLKEITSRTQIATEKKQIAQEKSQNVEVQSKEIEKEKGEAEAALVEALPVLEQARLALDDLEKNDVVEIRSFAKPPKPVQVVSECIAVFKNYKEINWKVAKGMMADPSFLQSLQTMDVDNITLKQSNVVRDSLDKLKIT-----IDEMRSVSKAGYGLLKFVTAVLGYTDVAREIKPKREKVARLEKTFGQNKRELEKVKNEIDKLESELKDLNQRYELAIDERQRLQEETDIMQRRLNAADKLINGLSSENKRWLVDLQLLKDQKVRLLGDCLVCSAFLSYVGAFSWEFRKEMVYSRWKDDVVERKIPM-SDPFRLEDILTNDVEISKWNSEGLPPDELSIQNGILTTRASRFPLCIDPQQQALNWIMQKEESNNLKTATFNDPDFLKQLELAIKYGIPFLFKDVDEYIDPVIDNVLEKNIKGDQGREFVILGDKEVDFDPNFRLYLNTKLSNPKYGPNIFGKSMVINYTVTLKGLEDQLLSVIVKFERKELEEQRERLIQETSDNKRLLKDLEDSLLRELATSTGNMLDNTELINTLEETKSKASEVSEKLKLGARTSEEIDKHRDGYREAAKRGAILFFVLAEMSTINSMYQYSLSAYLDVFKFSLKKSLPDGNLQKRLQNMMSTLTRNVYTYGCTGIFEKHKLLFTFQITLKLEMDKGNLTQDELDF-------FIKGNTSI--------EVAKRKKPYLWLSDISWQDVTKLT----------EMIPIKFSMLLEDIERDEYSWKQWINDETPETAA--LPKDYSN----KLGSFQK----LCLLRCFRIDRIYRAITLYVIEQMGEEYVTP--PILNFERIHD-QSTPFSPIVFILSPGSDPASDVVKLAERSGFGTTKLKFISMGQGQE-ANAKLLLDAAIARGHWLILQNCHLLVKWLRELEKDLERLTKPHPDFRLWLTTEPTEAFPIGILQRSLKVVTEPPNGLKLNLRSTYEKIALSSLNNFNHTAFP----SLVFTLAFFHAVVQERRKYGKIGWNIPYDFNESDFRVCIQILQTYLQKAA----DQGDSKIPWGSLKYLIGEVMYGGRAIDDFDRRILRTYMDEYFGDFLFDTFQPFHFYASKFATYLIPQCDTGDDQLKYIESLPLENTPEVFGLHSNAEIGYYTSAAKEMWSKLIDIQPQTGKS-----GSSQSRDEIINEKASGIKSKLPKLFDLDRLRKKYGLDISPTIVVLLQ----------------ELERFNILVDRMTKSLHTLMRALVGEVGMSAELDDVAKSLYNGQIPQIWKRLAPDTLKSLANWITHFNDRYTQYSQWVENGEPN--------VMWLSGLHIPESYLTALVQATCRKNGWPLDKSTLYTSVTQFATAAEVTERAHQGCFVHGLYLEGA 4542
BLAST of Cytoplasmic dynein 1 heavy chain 1 vs. Planmine SMEST
Match: SMESG000007049.1 (SMESG000007049.1) HSP 1 Score: 1395.18 bits (3610), Expect = 0.000e+0 Identity = 1001/3518 (28.45%), Postives = 1712/3518 (48.66%), Query Frame = 3 Query: 3594 TNESVNFITYTQNIKRKMNTWEKQAEACRAGQNILCRDRFQFPNDWLDSENIQGEWSAFKEIMRRKQETISSQVASLQMKITEEDKIVESKTTEVLGNWEKDKPIAGDLTPEEAVNIIQILEGKFNR--LKEERENVQKAKEALELTEIGVKPISEE-KVTNALSELHDLKNVWNELK---SIWEKIR--DMKETPWLSVQPRKLR-QDIENLTAQLKELPNSFKQYASFEHVRTLLK-----MYMKVNASIVELKSEAIKERHWRMLMRKLNVSWSLNE--LQLGKVWDIDLVKNEEIIREVLAIAQGEKALEEYLRQITEVWK--NYVLELTNYQSKSKIIKGWDDLFNKVKEHIN-NVTSMKASPYFKQFEEEATAWEDRLNKINALFDVWIDVQRRWIYLDGIFAGSADIKVLLPVESQRFQSVSTEFLGLMKKVQKSPLVTDVLNIANVQRQLERLADLLGKIQKSLGEYLERQRSSFPRFYFVGDEDLLEIIGNSXXXXXXXXXXXXMFAGVHSI--ILSEDEKV--------------------ILGMMSKEGEELRFISPVSIIEHPRINDWLTAMEKEMRVSLAKYLNVAVKEISGWRTESNIDKDKFMVWLDKYQAQIVVLAAQITWSEAVEASLASGVS--LESTMTV---VHSTLNMLADTVLYEQPPVRRRKLEHLIIEYVHQRDVLRALHNDGVSSNKNFDWMSQMRFYFDPKQTDPLHQLSIHVANAKFHYGFEYLGVCDRLVQTPLTDRCYLTMTQALEARLGGSPFGPAGTGKTESVKSLGNQLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLSAVSQQIQGIQEALRELMVSKKDSINVELLGKQVHVNPDMAIFITMNPGYAGRSNLPDNLKKLFRSLAMTQPDRQLIAQVMLYSQGFRTAEVLAGKVVPFFKLCDEQLSPQSHYDFGLRALKSVLVSAGNVKRDRIKQEKEKIVARGEEINETAIAEQLPEQEILIQSVMETMVPKLIADDIPLLYSLLTDVFPGVEYRQAEMKRLREELRKVSENKFLVYSDEPNTAGYLWVEKVLQLYQITTIHHGLMMVGPSGSGKTMACRVLLQALENIDGIEGVA-----------HIIDPKSISKDSLYGYMDPNTREWTDGLFTHILR-RIIDSVRGESNKRQWIVFDGDVDPEWVENLNSVLDDNKLLTLPNGERLAIPPNVRIMFEVQDLKYATLATVSRCGMVWFSEEVLTTGMILTHFLNELK---KVQVMEGEEDFSVNQGDTGADADSKISSSPIIQLQTQVSSILAPFFTEDGLIAKCLDYSTTLEHIMDFTRLRALTSLFSMIKQSIRNMIEYNQSHSDFPLNNEQIENYVAKSLISSVVWSMSGDSKLKVREQLSQYIKNI----STVDLPTVGGI-KNIIDFEVNIQGTWVAWSNKVPQIEVETHKITATDVVVPTMDTVRHEALLYTWLAEHRPVLLCGPPGSGKTMTLFSALRCLPDME---VVGLNFSSATTPELMLKTFDQYCEYRKTPNGIVLAPQQLNKWLIFFCDEINLPDMDKYGTQRVISFLRQMVEHHGFYRITDMQWVSFERIQFVGACNPPTDPGRKPLSHRFLRHVPVVYVDYPGETSLKQIYSTFNRAMLRMLPS-LRGYADTLTNAMVEFFLKTQERFTHDMQP-----HYIYSPREMTRWVRGIHEALKPLESLSVEGLVRIWAHEALRLFQDRLVEEDERHWTDDNINEVALKHF-PNINKEEALKRPILYSNWLSKDYSAVTQ--EELRDYVKAR--LKVFYEE-----ELDVPLVLFNQVLDHVLRIDRVFRQPQGHLLLIGVSGAGKTTLSRFVSWINGLSVFQVKVHNKYTAEDFDEDLRNVLRRSGCKGEKITFIMDESNVMDSSFLERMNTLLANGEVPGLFEGDELTTLMTQCKEGAIREGLMIDSQEELYKWFTQQICRNLHVVFTMNPSADGLKDKASTSPALFNRCVLNWFGDWSLEAYFQVGKEFTNRLDLERTDYKVPDTLPCIAEGLLPQNPIYRDVVVNALVFVHQTMHQANVRVQKRGGRTAAITPRHYLDLIAHYMKLSAEKRADLEEQQLHLNNGLKKIEQTVDQVEVMQRSLTKKRQELENMNEAANAKLKQMVQDQQEAE---QKKTTGQALKEELAKQEQFVNEKQKTVKQELDQVEPTVNEAKQAVQNIRKKDIQEIKAMKNPPNAVKMAVESICLLLGEKTTDWQSILKVIIKDTFVTSILNFNTDDVSDNTRETMKKKYLSNPDYNFEKVNKASNACGPMVKWVLAQISYADILKRVEPLRNEL----TELSDAAEQNRKKSQETEDLIAQLEKSIAKYTEEYATLISQAQTIKSDLASVESKVGRSVALLGSLSSERTRWDSGSETFKAQMATINGDCLLSSAFMAYGGYFDQHMRTSLFNTWCHHLSEADILFRSDLARVEYLSNPDDRLRWQANSLPADDLCVENAIILRRYNRYPLIIDPSGQATTFLLNEYKEKKITKTSFLDDSFRKTLESALRFGTPLLVQDV-ESYDPILNPVLNREVRRTGGRTLITLGDQDIDLSPTFTIFLSTRDPSVEFAPDICSRVTFVNFTVTRSSLQNQCLNAVLKIERPDIDQKRSDLLKAQGEFQLKLRHLEKDLLQSLNEAQGNLLENDKIIARLETLKREAADVAKKVEETDVVMQEVESVSTEYVPLAQSCSNIYFTLEAMNQIHFLYQYSLQLMLDIFSSVLINNPELTNVKAASDRLKIITKNLFQVTYNRLARGMLHEDQITFATILARIFLKGSTPIGFLENEFQHFLRSQEATITSSDSNKQDN-LGLTLHQDQIDSVKRLKKLKVFAKIEEKVKSTK---DIKNWTLTVTPESN--------VPELWVDDNNYNDEKLSKIAKGMYN--------LLIIQAIRPDRLLASTQKFIASVLGDTFTESVRGTLDLASIVEVEVTACVPILLCAVQGYDPSGRVEDLASEQG--KQLTGIAIGSAEGFSQAEKAINSAAKTGKWVMLKNVHLATSWLVSLEKKI-----HSLQAHPNFRLFLTMEITPKLPVNLLRAGRVLVFEPPPGIKANLLRTLSSINNQRMSKEPVER--SRLYFLLAWLNAIVQERLRYVPLGYSKKYEFGESDFKCALDTIDTWV-DGAAMGRTNLPPEKIPWVALQTLLGSCIYGGKIDNAFDQRLLNSFLGYLFTEKCFDHNFALVSDADDGSNIAF-PESTKHTDILQWVHKLPDLQTPSWLGLPNSAEKVLLTNLGQSLIGNILKMQQSLEDDEELVVGQSKTKRTIEVGDGRPAWMRQLYQSTQTWLQILPKSVTPLQRTIENIKDPMYRCFER------------EVNSGCNLLASVRKDLEDVAEVCKGAKKPTNHHRSMMADLAKGIIPKMWIRYAIPPGLTVIQWIQDFADRIKQ-LLHISDTAAKSGVIALRSIQVWLGGLFMAEAYITATRQSVAQNNKWALEEL 13736 T + VN + + I+ +M E++A+ + +++ D F P D Q + + + R + I +A I DK S ++ + K I +A+N IL+ K N+ +KEE E ++ L+ K + KV A + DL+ V ELK +W+ + D + WL + KL +D+ TA+ ++ ++ V +LK M K++ I L + ++ERHW+ + +N +S +E L LGK+ ++++ +E + E+ A E +LE L+++ E W+ YV+ L + SK I G D ++ + N NV ++ +S + + W L+ + W++ QR W+YL+ IF+ + DI+ LP E++ F SV + +M+KVQK PL + + LL +IQK L YLE +R FPRFYF+ +++LLEI+ +++ +Q H +K F + + ++E KV IL M+S EGE++ + + +WL +E+ M ++L K L ++ E E WL + QIV+ Q+ W + A L V L+ + LN LA V P + R L LI VH RD++ + + VS F+W Q+R+Y+D L + ++N+ + YG+EYLG RLV TPLTDRCYL + AL+ LGG+P GPAGTGKTE+ K L L + +VFNC + D++ MGR F GL Q GAW CFDEFNR++ +LS ++QQ+ I+ A +K E G+++ + A FITMNPGYAGR+ LPDNLK LFR +AM PD +LIA+V+LYS+GF +++ LA K+ +KLC EQLS Q HYDFG+RALKSVLV AG +KR+ + PE +LI+++ ++ +PK + D L ++L D+FPGVE + + R + E+ V EN L + N + L KV+Q Y+ + HG+M+VGP+G GKT VL + L N++ G+A +I++PKSI+ LYG ++ T EW DGL +I+R +D+ S QW++ DG VD W+EN+N+VLDDNK+L L N ER+ + P V ++FEVQDL A+ ATVSRCGMV+ E L + +LN + K++V+ D+ + D K + + IQ QVS IAK T R L SL + ++ +++ +A + + +W + G+ + +++N +P+ G + + D W K+ + ++ +++VPT+DT+R LL L + VL G G GK++ L + + V +NFS+ T+ + + E ++ ++ AP NK +I F D++N+P +D YG+Q I LRQ + GFY + W++ + + AC PP GR P+S R LRH + + P E SL+QI+++ P +RG + + A VE + R D+ P HY+++ R++++ ++GI + P G+ +++ HEA R+F DRL+ +++ + + E+A K+F NI E +K PI++ +++ + E L D+ K + L + ++ ++ LV F +DH+ RI R+ RQ +G+ LL+GV G GK +L+R +++NG + FQ+++ Y F DL+ + +G + F+ ++ ++ FLE +N +L +GEVP LFE DE ++ C+ A G+ +++ ++++ ++ NLH+V M+P + + P+L N C ++WF W EA V K +D+ + KV L C +H ++ + + R R TP YL+LI Y+ + EK+ L ++ + NGL KI +T + + M+ L R +LE + A ++++ DQ++A+ K +A+ + AK+ Q + + +++LD+ P + A +A+ + K DI EI+ NPP V+ +ES+CLLLG+K TDW S V+ F+ + ++ D++ + + + K+Y+ +P++ E V K S AC +V WV A Y+ +K VEP + L EL + + R+K E + +E IA+ + Y +++ + ++ +LA +++ R+ L +L+ E+ RW F ++ + GD + +A +AY G F R L + W E +I + + L + + +W + LP D + ENAI++ R R+PL+IDP QA ++ N+ ++ + +F +TLE+ +R G P L++D+ E+ DP L P+L ++ GRTLI LGD DI+ S F ++++T+ + + P+IC +VT +NFTVT L++Q L V ++ERP+++++R++L+ + +L+ E +L+ L E++GN+L+++ +I L K +A+ K++ E ++ Q++ ++Y+P+A S +YF + M +I +YQ+SL+ +F++ + N+ + +++ +R+KI+ TYN +ARG+ +D++ F+ +L ++ + I +E EF FLR D + L + + +D + VF+ + + I T++V E N VP + D + +K G Y+ L++++ ++++ +F+ LG F E L L + +++ P++ G DP + + A E+ +++ I++G +G AEK +++AAK G WV L+N HLA SW+V LE+ + + + H NFRLFL+ P+++L+ + EPP G++AN+ R + ++ Q + +L F + + ++I+ +R ++ PLG++ +YEF +SD +CA+ + + DG I W AL + YGG++ + +DQR L + L F K ++ S I + PE + +V LP L+ P G+ +A Q LI IL +Q + T RT + +Y+ L+ L + P E K ++ E+ EV+ LL+ ++ L + + KG + S+ +P +W A P + W++D A R + A KS WL G F + ++T T Q+ A+ + ++ L Sbjct: 744 TVDYVNALNFLSEIQVRMEPLEREADVIKEMYDLI--DAFNVPTPPEDFAVYQTLYPS----IDRAKNAIDKALADRDGNI---DKFCASLDKDIAELRREVKDI------RQAINNPLILDVKANKHEVKEELEKLKNTMNELQTRAFTYKSYQKNFKVEQA--RMEDLEEVAAELKLKQILWDSLDEWDSRYNEWLREEFMKLNPEDLGTQTAKYVKIVAQLEKGLPPNQVVPVLKDKVEQMREKMSV-ITNLLNPCLQERHWQQIEDIINYKFSESEEKLTLGKLIELNVFDYKEELEEISGQASSEASLEALLKKVEEAWQITEYVV-LPHKDSKDVFILGGTDEIQQLWDDSNINVATIASSRHVGPIKPRVDEWVKNLDLFGKTIEEWLNCQRNWLYLESIFS-APDIQRQLPSEAKSFMSVDKSYKEIMRKVQKVPLAMRATTTPGLLDTFKNNNQLLDQIQKCLEAYLESKRVIFPRFYFLSNDELLEILAQTRNPLAVQPHLRKCFDAISKLDFAIAETPKVESSDGMPQTPQPQEVKYTNDILAMISPEGEKVSLGK--GLKARGNVEEWLGKVEEAMFLNLRKLLRQSITEFDTLEREE---------WLKAHANQIVLTVEQMMWCREITAILEDVVEERLQGMIDFEVKCFQDLNKLAGLVRGVLPKLFRATLCALITVNVHARDMVTEMVKEKVSDINCFEWQKQLRYYWD----STLDNCVVRMSNSLYTYGYEYLGCSPRLVITPLTDRCYLCLMGALQLDLGGAPAGPAGTGKTETTKDLAKSLAKQCVVFNCSDGLDYKMMGRFFSGLAQSGAWCCFDEFNRIDIEVLSVIAQQLITIRNA----KAAKISRFMFE--GREIKLVMTCAAFITMNPGYAGRTELPDNLKALFRPIAMMVPDYRLIAEVILYSEGFESSKTLAQKMTQMYKLCSEQLSQQDHYDFGMRALKSVLVMAGQLKRENPDK---------------------PEDVVLIRALRDSNLPKFLKQDAELFRAILQDLFPGVELPEHDYGRFKLEIEYVIENSGL----QINPSQVL---KVIQFYETLAVRHGVMLVGPTGGGKTTVYNVLAKVLSNLNA-AGLAEERPDYQPVKMYILNPKSITMGELYGEVNKLTLEWHDGLMPYIVRITCVDT----SQDHQWVICDGPVDALWIENMNTVLDDNKMLCLANSERIKLTPYVHMLFEVQDLSVASPATVSRCGMVYVDPEELGWMPFVKTWLNSMTGKLKIEVI----DYLYGMFEKYIDDGLKFAQTKCIQTMAQVS------------IAKIQ------------TMCRLLESLL------------VGPGAPNLNVDAQKLNPTIAIAFVFCYLWGIGGNLHESNWDSFDNFVRNKFEDNGDCRMPSQGDLWSSYADLHSRKMDLW----EKIVPVFKFNKEVPFFEMIVPTVDTIRFGYLLEKLLHVKQSVLFTGATGVGKSVVARGTLNNISENAGYVPVFINFSAQTSSNRTQEMIENKLEKKR--KAVLGAPT--NKRVIIFIDDLNMPKLDTYGSQPPIELLRQYQDFGGFYDRDKLNWITIQDMTLSAACGPPGG-GRNPVSARLLRHFAMFSIPAPSEISLRQIFTSILTGFFADFPQQVRGCTENIVLAAVEIY----NRMYTDLLPTPAKSHYVFNLRDLSKCIQGILQC-DPSCVRDKSGVFKLFCHEAQRVFHDRLINHEDKMFFHQIVAEMASKYFGENIEPESFIKLPIIFGDFMKPGLEKHERLYEPLTDFAKVKNILHSYLDDFNMASSKEMKLVFFMDAIDHIARIARMIRQDRGNALLVGVGGTGKQSLTRLAAFMNGYNCFQIELCRGYDYNMFHTDLKKIYEWTGINNQHTVFLFTDTQIVVEEFLEDINNILNSGEVPSLFEPDEYERMIIGCRAAAKEAGVSEGNRDGIFEFCINRVRNNLHIVLCMSPVGSSFRSRCRMFPSLVNCCTIDWFTAWPEEALLNVAKSSFEHVDIGEDELKVKLALMCTE--------------------IHTSVAKESERFYAELKRHYYTTPTSYLELITLYLSMLTEKKKQLVTRRDRVKNGLTKILETNELIATMEVELVALRPQLEQKQKDTEALMQKLGTDQEQADIVRDKVKEDEAVAKVKAKETQAIADD---AQRDLDEAMPALENAIKALDALDKNDIAEIRVFTNPPQMVQTVMESVCLLLGQK-TDWASAKSVLGDPYFLKKLADYPKDNIPEALLKKL-KRYIDDPNFTAENVEKVSKACRSLVLWVRAMDIYSKTVKTVEPKKKRLEIANKELDEVMGKLRQKQAE----LLAVENKIAELQKIYDNSVTEKKALEHNLALTSARLKRAGKLTTALADEKERWTESVSKFNEELGNVVGDVFMGAACVAYYGAFTSSYRHELLSGWIGRCRELEIPVSEHITLMGVLGDAFELRQWNSEGLPRDQVSTENAILVTRGRRWPLMIDPQEQANRWIRNKETVNQLKIIKLSEGNFLRTLENCIRLGMPALLEDIGETLDPALEPILLKQTFVKAGRTLIHLGDSDIEYSKDFKLYITTKLSNPHYMPEICIKVTIINFTVTPQGLEDQLLGEVTRLERPELEEQRNNLIIRINNDKNQLQITENRILKLLFESEGNILDHEDLINTLNESKVTSAETTKRIAEAELTEQKITVARSKYIPVAGRGSVMYFVVANMAEIDPMYQFSLKYFKTLFNNTIENSQKSQDLE---ERIKILLAETTIATYNNVARGLFEKDKLVFSFMLCIQIMRQNGLISDMEWEF--FLRGIGGIEKKRPEKPHDPWISLNVWNNVVDVS---DIIPVFSNLINDITQMHIEVTIGELTISVNEEQNDSYRPLPPVPSEEAIQKSRLDSEFAKSLSGHYDLRLASFQKLILVKTFCEEKIVLCITEFVKLNLGTRFVEPPPTDLPL---LFQDMSKVSPLVFVLSTGSDPMNQFQRFAKEKNYMERVQAISLGQGQG-PVAEKMMDAAAKIGDWVFLQNCHLAASWMVRLEEIVKKRSENPYEVHENFRLFLSSMPAKTFPISVLQNSVKVTNEPPKGLRANIKRAFNEMSPQFFETHVLGLVWRKLIFGICFFHSIILDRKKFGPLGWNIRYEFSDSDRECAILNLGMFCADGV-----------IQWDALTYITAEITYGGRVTDFWDQRCLRNILTTFFHPKTIVEDYKYSQ-----SGIYYPPEFETINEYKDFVDSLPLLEEPEIFGMHENANLSFQIQETQKLINTILDVQPR--------IAAGGTGRTTD---------DIVYELADQILEKLIDKINP-----EEAKPDLFHPDEKGRLNSLTTVLMQEVDRFNKLLSVIKNSLVQLKKAIKGFVVMSEELESVYTAFTNNQVPNLWSNVAYPSLKPLSTWVKDLAMRCSSTYFWMVQGAPKS---------FWLPGFFFPQGFLTGTLQNYARKYDYPIDHL 4045 The following BLAST results are available for this feature:
BLAST of Cytoplasmic dynein 1 heavy chain 1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Cytoplasmic dynein 1 heavy chain 1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Cytoplasmic dynein 1 heavy chain 1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Cytoplasmic dynein 1 heavy chain 1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Cytoplasmic dynein 1 heavy chain 1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Cytoplasmic dynein 1 heavy chain 1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Cytoplasmic dynein 1 heavy chain 1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Cytoplasmic dynein 1 heavy chain 1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Cytoplasmic dynein 1 heavy chain 1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Cytoplasmic dynein 1 heavy chain 1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of Cytoplasmic dynein 1 heavy chain 1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 1 |