O-acyltransferase
Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30008540 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 4
Homology
BLAST of O-acyltransferase vs. Ensembl Human
Match: SOAT1 (sterol O-acyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:11177]) HSP 1 Score: 395.586 bits (1015), Expect = 6.122e-131 Identity = 234/550 (42.55%), Postives = 310/550 (56.36%), Query Frame = 1 Query: 73 SLDGEIRNRRINETGIVKDYENQFSDDNATKFFQKINWKEKTEKKQKEFIDNVE------KDMKLMFGKLKEVIIEEYDEMTN--------ETLDSPKKLCNINLKHDMLPEKQ---FQNRESVLTNLLNISHIRTVYHMFVAILIIFSLNTMLTDLIEKGGIIHTYHLEWVFWAFGGIGDVILLWLSMKSFTIFVYPCFL--SWL--YVRRMKILPISCVNKIYLVVYILTQISFVVIPLYFMCLIDLPPCSSAIVVLENIRLAMKIHAFIRENV------AKELKSNELIETINFSRYLYFLFAPTLIYRDSYPKNPTIRWSYVVSNFAQVIFCIVYMYYIFARFCVVYFQNFNSIHVTMQQLVLSVFGCMLPATLVFFICFFCFLHSWLNAFAEMLQFGDRLFYKEWWNSTTFSNYYRTWNVVVHDWLYTYVYRDILLLCRFNNRAAAMTIVFLFSAVFHEYVLIVMFRFFYPVLFVLFSGVGFGMMFIKGRAR---IWNIGFWVAMFTGNGIIMCLYSMEWYARRNCPIYFSTFVDLLVPRSWFCQ 1632 SL + R N +D N + T +I+ K+ KK K + E K++ F +IE+ + N L+ K N K P +Q F R S+L LL + HIRT+YHMF+A+LI+F L+T++ D I++G ++ + L + +AFG V+ W M + F P FL W Y + L S + +++ + + F P Y + LPP S I++ E IR MK H+F+RENV AKE S I T+N +YLYFLFAPTLIYRDSYP+NPT+RW YV FAQV C Y+YYIF R C F+N + + LVL VF +LP L+ F+ FF FLH WLNAFAEML+FGDR+FYK+WWNST++SNYYRTWNVVVHDWLY Y Y+D L ++AAM VF SAV HEY L V FFYPVLFVLF G FI +R IWN+ W ++F GNG+++C YS EWYAR++CP+ TF+D + PRSW C+ Sbjct: 8 SLRNRLSKSRENPEED-EDQRNPAKESLETPSNGRIDIKQLIAKKIKLTAEAEELKPFFMKEVGSHFDDFVTNLIEKSASLDNGGCALTTFSVLEGEKN--NHRAKDLRAPPEQGKIFIARRSLLDELLEVDHIRTIYHMFIALLILFILSTLVVDYIDEGRLVLEFSL--LSYAFGKFPTVVWTWWIM-FLSTFSVPYFLFQHWATGYSKSSHPLIRSLFHGFLFMIFQIGVLGFG--PTYVVLAYTLPPASRFIIIFEQIRFVMKAHSFVRENVPRVLNSAKEKSSTVPIPTVN--QYLYFLFAPTLIYRDSYPRNPTVRWGYVAMKFAQVFGCFFYVYYIFERLCAPLFRNIKQEPFSARVLVLCVFNSILPGVLILFLTFFAFLHCWLNAFAEMLRFGDRMFYKDWWNSTSYSNYYRTWNVVVHDWLYYYAYKDFLWFFSKRFKSAAMLAVFAVSAVVHEYALAVCLSFFYPVLFVLFMFFGMAFNFIVNDSRKKPIWNVLMWTSLFLGNGVLLCFYSQEWYARQHCPLKNPTFLDYVRPRSWTCR 547
BLAST of O-acyltransferase vs. Ensembl Human
Match: SOAT1 (sterol O-acyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:11177]) HSP 1 Score: 390.963 bits (1003), Expect = 5.714e-130 Identity = 213/439 (48.52%), Postives = 275/439 (62.64%), Query Frame = 1 Query: 361 PE--KQFQNRESVLTNLLNISHIRTVYHMFVAILIIFSLNTMLTDLIEKGGIIHTYHLEWVFWAFGGIGDVILLWLSMKSFTIFVYPCFL--SWL--YVRRMKILPISCVNKIYLVVYILTQISFVVIPLYFMCLIDLPPCSSAIVVLENIRLAMKIHAFIRENV------AKELKSNELIETINFSRYLYFLFAPTLIYRDSYPKNPTIRWSYVVSNFAQVIFCIVYMYYIFARFCVVYFQNFNSIHVTMQQLVLSVFGCMLPATLVFFICFFCFLHSWLNAFAEMLQFGDRLFYKEWWNSTTFSNYYRTWNVVVHDWLYTYVYRDILLLCRFNNRAAAMTIVFLFSAVFHEYVLIVMFRFFYPVLFVLFSGVGFGMMFIKGRAR---IWNIGFWVAMFTGNGIIMCLYSMEWYARRNCPIYFSTFVDLLVPRSWFCQ 1632 PE K F R S+L LL + HIRT+YHMF+A+LI+F L+T++ D I++G ++ + L + +AFG V+ W M + F P FL W Y + L S + +++ + + F P Y + LPP S I++ E IR MK H+F+RENV AKE S I T+N +YLYFLFAPTLIYRDSYP+NPT+RW YV FAQV C Y+YYIF R C F+N + + LVL VF +LP L+ F+ FF FLH WLNAFAEML+FGDR+FYK+WWNST++SNYYRTWNVVVHDWLY Y Y+D L ++AAM VF SAV HEY L V FFYPVLFVLF G FI +R IWN+ W ++F GNG+++C YS EWYAR++CP+ TF+D + PRSW C+ Sbjct: 51 PEQGKIFIARRSLLDELLEVDHIRTIYHMFIALLILFILSTLVVDYIDEGRLVLEFSL--LSYAFGKFPTVVWTWWIM-FLSTFSVPYFLFQHWATGYSKSSHPLIRSLFHGFLFMIFQIGVLGFG--PTYVVLAYTLPPASRFIIIFEQIRFVMKAHSFVRENVPRVLNSAKEKSSTVPIPTVN--QYLYFLFAPTLIYRDSYPRNPTVRWGYVAMKFAQVFGCFFYVYYIFERLCAPLFRNIKQEPFSARVLVLCVFNSILPGVLILFLTFFAFLHCWLNAFAEMLRFGDRMFYKDWWNSTSYSNYYRTWNVVVHDWLYYYAYKDFLWFFSKRFKSAAMLAVFAVSAVVHEYALAVCLSFFYPVLFVLFMFFGMAFNFIVNDSRKKPIWNVLMWTSLFLGNGVLLCFYSQEWYARQHCPLKNPTFLDYVRPRSWTCR 482
BLAST of O-acyltransferase vs. Ensembl Human
Match: SOAT1 (sterol O-acyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:11177]) HSP 1 Score: 391.349 bits (1004), Expect = 5.946e-130 Identity = 213/439 (48.52%), Postives = 275/439 (62.64%), Query Frame = 1 Query: 361 PE--KQFQNRESVLTNLLNISHIRTVYHMFVAILIIFSLNTMLTDLIEKGGIIHTYHLEWVFWAFGGIGDVILLWLSMKSFTIFVYPCFL--SWL--YVRRMKILPISCVNKIYLVVYILTQISFVVIPLYFMCLIDLPPCSSAIVVLENIRLAMKIHAFIRENV------AKELKSNELIETINFSRYLYFLFAPTLIYRDSYPKNPTIRWSYVVSNFAQVIFCIVYMYYIFARFCVVYFQNFNSIHVTMQQLVLSVFGCMLPATLVFFICFFCFLHSWLNAFAEMLQFGDRLFYKEWWNSTTFSNYYRTWNVVVHDWLYTYVYRDILLLCRFNNRAAAMTIVFLFSAVFHEYVLIVMFRFFYPVLFVLFSGVGFGMMFIKGRAR---IWNIGFWVAMFTGNGIIMCLYSMEWYARRNCPIYFSTFVDLLVPRSWFCQ 1632 PE K F R S+L LL + HIRT+YHMF+A+LI+F L+T++ D I++G ++ + L + +AFG V+ W M + F P FL W Y + L S + +++ + + F P Y + LPP S I++ E IR MK H+F+RENV AKE S I T+N +YLYFLFAPTLIYRDSYP+NPT+RW YV FAQV C Y+YYIF R C F+N + + LVL VF +LP L+ F+ FF FLH WLNAFAEML+FGDR+FYK+WWNST++SNYYRTWNVVVHDWLY Y Y+D L ++AAM VF SAV HEY L V FFYPVLFVLF G FI +R IWN+ W ++F GNG+++C YS EWYAR++CP+ TF+D + PRSW C+ Sbjct: 58 PEQGKIFIARRSLLDELLEVDHIRTIYHMFIALLILFILSTLVVDYIDEGRLVLEFSL--LSYAFGKFPTVVWTWWIM-FLSTFSVPYFLFQHWATGYSKSSHPLIRSLFHGFLFMIFQIGVLGFG--PTYVVLAYTLPPASRFIIIFEQIRFVMKAHSFVRENVPRVLNSAKEKSSTVPIPTVN--QYLYFLFAPTLIYRDSYPRNPTVRWGYVAMKFAQVFGCFFYVYYIFERLCAPLFRNIKQEPFSARVLVLCVFNSILPGVLILFLTFFAFLHCWLNAFAEMLRFGDRMFYKDWWNSTSYSNYYRTWNVVVHDWLYYYAYKDFLWFFSKRFKSAAMLAVFAVSAVVHEYALAVCLSFFYPVLFVLFMFFGMAFNFIVNDSRKKPIWNVLMWTSLFLGNGVLLCFYSQEWYARQHCPLKNPTFLDYVRPRSWTCR 489
BLAST of O-acyltransferase vs. Ensembl Human
Match: SOAT2 (sterol O-acyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:11178]) HSP 1 Score: 370.933 bits (951), Expect = 1.090e-121 Identity = 193/526 (36.69%), Postives = 288/526 (54.75%), Query Frame = 1 Query: 82 GEIRNRRINETGIVKDYENQFSDDNATKFFQK---INWKEKTEKKQKEFIDNVEKDMKLMFGKLKEVIIEEYDEMTNETLDSPKKLCNINLKHDMLPEKQFQNRESVLTNLLNISHIRTVYHMFVAILIIFSLNTMLTDLIEKGGIIHTYHLEWVFWAFGGIGDVILLWLSMKSFTIFV-YPCFLSWLYVRRMKILPISCVNKIYLVVYILTQISFVVIPLYFMCLIDLPPCSSAIVVLENIRLAMKIHAFIRENVAKELKS--NELIETINFSRYLYFLFAPTLIYRDSYPKNPTIRWSYVVSNFAQVIFCIVYMYYIFARFCVVYFQNFNSIHVTMQQLVLSVFGCMLPATLVFFICFFCFLHSWLNAFAEMLQFGDRLFYKEWWNSTTFSNYYRTWNVVVHDWLYTYVYRDILLLCRFNNRAAAMTIVFLFSAVFHEYVLIVMFRFFYPVLFVLFSGVGFGMMFIKGRARI---WNIGFWVAMFTGNGIIMCLYSMEWYARRNCPIYFSTFVDLLVPRSWFCQ 1632 G R R G+ + E Q D T+ + + W E + + ++ + ++ + + I+ Y P + + + +K F R+S+L L+ + H RT+YHMF+A L +F ++T+ D I++G ++ + L + ++FG + ++ W+ M T+ Y W + + C + + +P++ LPP S ++V E +R MK ++F+RE V L++ E I+ +FS YLYFLF PTLIYR++YP+ P +RW+YV NFAQ + C++Y +I R CV F N + + + LVLS+ LP + + FF FLH WLNAFAEML+FGDR+FY++WWNST+FSNYYRTWNVVVHDWLY+YVY+D L L R AM VFL SAV HEY+ + FFYPV+ +LF +G + F+ R WN+ W +F G GI + LY EWYARR+CP+ +TF L+ PRSW C Sbjct: 4 GGARLRLQRTEGLGGERERQPCGDGNTETHRAPDLVQWTRHMEAVKAQLLEQAQGQLRELLDRAMREAIQSYPSQDKPLPPPPPGSLSRTQEPSLGKQKVFIIRKSLLDELMEVQHFRTIYHMFIAGLCVFIISTLAIDFIDEGRLLLEFDL--LIFSFGQLPLALVTWVPMFLSTLLAPYQALRLWARGTWTQATGLGCA------LLAAHAVVLCALPVHVAVEHQLPPASRCVLVFEQVRFLMKSYSFLREAVPGTLRARRGEGIQAPSFSSYLYFLFCPTLIYRETYPRTPYVRWNYVAKNFAQALGCVLYACFILGRLCVPVFANMSREPFSTRALVLSILHATLPGIFMLLLIFFAFLHCWLNAFAEMLRFGDRMFYRDWWNSTSFSNYYRTWNVVVHDWLYSYVYQDGLRLLGARARGVAMLGVFLVSAVAHEYIFCFVLGFFYPVMLILFLVIGGMLNFMMHDQRTGPAWNVLMWTMLFLGQGIQVSLYCQEWYARRHCPLPQATFWGLVTPRSWSCH 521
BLAST of O-acyltransferase vs. Ensembl Human
Match: SOAT2 (sterol O-acyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:11178]) HSP 1 Score: 121.709 bits (304), Expect = 5.728e-30 Identity = 80/311 (25.72%), Postives = 145/311 (46.62%), Query Frame = 1 Query: 82 GEIRNRRINETGIVKDYENQFSDDNATKFFQK---INWKEKTEKKQKEFIDNVEKDMKLMFGKLKEVIIEEYDEMTNETLDSPKKLCNINLKHDMLPEKQFQNRESVLTNLLNISHIRTVYHMFVAILIIFSLNTMLTDLIEKGGIIHTYHLEWVFWAFGGIGDVILLWLSMKSFTIFV-YPCFLSWLYVRRMKILPISCVNKIYLVVYILTQISFVVIPLYFMCLIDLPPCSSAIVVLENIRLAMKIHAFIRENVAKELKS--NELIETINFSRYLYFLFAPTLIYRDSYPKNPTIRWSYVVSNFAQVIF 996 G R R G+ + E Q D T+ + + W E + + ++ + ++ + + I+ Y P + + + +K F R+S+L L+ + H RT+YHMF+A L +F ++T+ D I++G ++ + L + ++FG + ++ W+ M T+ Y W + + C + + +P++ LPP S ++V E +R MK ++F+RE V L++ E I+ +FS YLYFLF PTLIYR++YP+ P S S++A +F Sbjct: 4 GGARLRLQRTEGLGGERERQPCGDGNTETHRAPDLVQWTRHMEAVKAQLLEQAQGQLRELLDRAMREAIQSYPSQDKPLPPPPPGSLSRTQEPSLGKQKVFIIRKSLLDELMEVQHFRTIYHMFIAGLCVFIISTLAIDFIDEGRLLLEFDL--LIFSFGQLPLALVTWVPMFLSTLLAPYQALRLWARGTWTQATGLGC------ALLAAHAVVLCALPVHVAVEHQLPPASRCVLVFEQVRFLMKSYSFLREAVPGTLRARRGEGIQAPSFSSYLYFLFCPTLIYRETYPR-PWDVCSMPASSWAASVF 305
BLAST of O-acyltransferase vs. Ensembl Celegans
Match: mboa-1 (O-acyltransferase [Source:UniProtKB/TrEMBL;Acc:Q17498]) HSP 1 Score: 254.603 bits (649), Expect = 6.254e-78 Identity = 158/455 (34.73%), Postives = 230/455 (50.55%), Query Frame = 1 Query: 301 NETLDSPKKLCNINLKHDMLPEKQFQNRESVLTNLLNISHIRTVYHMFVAILIIFSLNTMLTD-LIEKGGIIHTYHLEWVFWAFGGIGDVILLWLSMKSFTIFVYPCFLSWLYVRRMKILPISCVNKIYLVVYILTQISFVVIPLYFMCLIDLPPCSSAIVVLENIRLAMKIHAFIRENVAKELKSNELIETIN----FSRYLYFLFAPTLIYRDSYPKNPTIRWSYVVSNFAQVIFCIVYMYYIFARFCVVYFQNFNSIHVTMQQLVLSVFGCMLPATLVFFICFFCFLHSWLNAFAEMLQFGDRLFYKEWWNSTTFSNYYRTWNVVVHDWLYTYVYRDILLL--CRFNNRAAAMTIVFLFSAVFHEYVLIVMFRFFYPVLFVL---FSGVGFGMMFIKGRARIWNIGFWVAMFTGNGIIMCLYSMEWYARR-NCPIYFSTFVDLLVPRSWFCQ 1632 N L + ++ K EK F RES+LT+ H++ +Y+ F A ++F L M+ D L+ K HT+ ++W F + +W M TI VY + W + S N ++ Y+ +F PL F+ DL S I+ E R+AMK+H+FIREN + +K ++ TI+ ++LY+ F P+ IYRDSYP+ F + + I ++ F ++ + + ++ + LS+F ++P + F+ LH WLN F+EM+QF DR FY WW+S+ + YYR WN+VVHDWLY YV+RD+ R RAA M + FL SAVFHEY V FR FYPV+FVL F G F + + WN W + G G+ + Y EWYARR +C Y + VDLL PR W C Sbjct: 16 NVILKEHHEQVSVKHKKREFKEKTFVVRESLLTSEFRNGHMKIIYNCFTAAFLLFFLRAMIDDILVHKMPFHHTWL---IWWNFQNFIPTMAVWTGMFLSTIGVYYAYEHWSTIPSKNTDLAS--NLPFVTAYVTYLAAFFYFPLKFLYESDLKCACSFIITCETTRIAMKVHSFIRENWDRAMK-RKIGGTIDAWPTMEQFLYYQFCPSFIYRDSYPRTEKRDMKAAGLYFLECLAVIEFVNLTFTQWVFPWLHVQDYTSLSFSTIALSLFTGIIPGIICMTSLFYGLLHCWLNCFSEMMQFADRQFYLNWWHSSNMAEYYRNWNLVVHDWLYAYVFRDLAAYNPGRKGQRAAQMAVFFL-SAVFHEYWFGVAFRCFYPVMFVLYFIFGGTFFAVSRLITNRSAWNTALWFNLLIGTGMFIAFYGQEWYARRGHCAPYSNAVVDLLFPRHWNCH 463
BLAST of O-acyltransferase vs. Ensembl Celegans
Match: mboa-2 (O-acyltransferase [Source:UniProtKB/TrEMBL;Acc:F1LIN4]) HSP 1 Score: 86.2705 bits (212), Expect = 3.314e-18 Identity = 67/260 (25.77%), Postives = 133/260 (51.15%), Query Frame = 1 Query: 823 IRENVAKELKSNELIETINFSRYLYFLFAPTLIYRDSYPKNPTIRWSYVVSNFAQVIFCIVYMYYIFARFCVVYFQNFNSIHVTMQ--QLVLSVFGCMLPATLVFFICFFCFLHSWLNAFAEMLQFGDRLFYKEWWNSTTFSNYYRTWNVVVHDWLYTYVYRDILLLCRFN-NRAAAMTIVFLFSAVFHEYVLIVMFRFFYPVLFVLFSGVGFGMM-----------FIKGRARIWNIGFWVAMFTGNGIIMCLYSMEWY 1560 +++ ++ + + + S YF+ APTL Y +P+ IR +++ ++IF + + ++ V +N M+ + + + +P L++ + F+ F HS+LN AE+L+F DR FY+++WN+ T ++++WN+ VH + ++Y ++ R N ++ +A +VF SA FHEY++ V + +F L+S +GMM ++G R NI W+++ G + + +Y +WY Sbjct: 52 LKDELSMHQMAAQYPANLTLSNIYYFMAAPTLCYEFKFPRLLRIRKHFLIKRTVELIFLSFLIAALVQQWVVPTVRNSMKPLSEMEYSRCLERLLKLAIPNHLIWLLFFYTFFHSFLNLIAELLRFADREFYRDFWNAETIGYFWKSWNIPVHRFAVRHIYSPMM---RNNFSKMSAFFVVFFVSAFFHEYLVSVPLK-----IFRLWS--YYGMMGQIPLSIITDKVVRG-GRTGNIIVWLSLIVGQPLAILMYGHDWY 300
BLAST of O-acyltransferase vs. Ensembl Celegans
Match: mboa-2 (O-acyltransferase [Source:UniProtKB/TrEMBL;Acc:F1LIN4]) HSP 1 Score: 86.2705 bits (212), Expect = 3.314e-18 Identity = 67/260 (25.77%), Postives = 133/260 (51.15%), Query Frame = 1 Query: 823 IRENVAKELKSNELIETINFSRYLYFLFAPTLIYRDSYPKNPTIRWSYVVSNFAQVIFCIVYMYYIFARFCVVYFQNFNSIHVTMQ--QLVLSVFGCMLPATLVFFICFFCFLHSWLNAFAEMLQFGDRLFYKEWWNSTTFSNYYRTWNVVVHDWLYTYVYRDILLLCRFN-NRAAAMTIVFLFSAVFHEYVLIVMFRFFYPVLFVLFSGVGFGMM-----------FIKGRARIWNIGFWVAMFTGNGIIMCLYSMEWY 1560 +++ ++ + + + S YF+ APTL Y +P+ IR +++ ++IF + + ++ V +N M+ + + + +P L++ + F+ F HS+LN AE+L+F DR FY+++WN+ T ++++WN+ VH + ++Y ++ R N ++ +A +VF SA FHEY++ V + +F L+S +GMM ++G R NI W+++ G + + +Y +WY Sbjct: 52 LKDELSMHQMAAQYPANLTLSNIYYFMAAPTLCYEFKFPRLLRIRKHFLIKRTVELIFLSFLIAALVQQWVVPTVRNSMKPLSEMEYSRCLERLLKLAIPNHLIWLLFFYTFFHSFLNLIAELLRFADREFYRDFWNAETIGYFWKSWNIPVHRFAVRHIYSPMM---RNNFSKMSAFFVVFFVSAFFHEYLVSVPLK-----IFRLWS--YYGMMGQIPLSIITDKVVRG-GRTGNIIVWLSLIVGQPLAILMYGHDWY 300
BLAST of O-acyltransferase vs. Ensembl Celegans
Match: mboa-2 (O-acyltransferase [Source:UniProtKB/TrEMBL;Acc:F1LIN4]) HSP 1 Score: 85.8853 bits (211), Expect = 1.967e-17 Identity = 67/260 (25.77%), Postives = 133/260 (51.15%), Query Frame = 1 Query: 823 IRENVAKELKSNELIETINFSRYLYFLFAPTLIYRDSYPKNPTIRWSYVVSNFAQVIFCIVYMYYIFARFCVVYFQNFNSIHVTMQ--QLVLSVFGCMLPATLVFFICFFCFLHSWLNAFAEMLQFGDRLFYKEWWNSTTFSNYYRTWNVVVHDWLYTYVYRDILLLCRFN-NRAAAMTIVFLFSAVFHEYVLIVMFRFFYPVLFVLFSGVGFGMM-----------FIKGRARIWNIGFWVAMFTGNGIIMCLYSMEWY 1560 +++ ++ + + + S YF+ APTL Y +P+ IR +++ ++IF + + ++ V +N M+ + + + +P L++ + F+ F HS+LN AE+L+F DR FY+++WN+ T ++++WN+ VH + ++Y ++ R N ++ +A +VF SA FHEY++ V + +F L+S +GMM ++G R NI W+++ G + + +Y +WY Sbjct: 234 LKDELSMHQMAAQYPANLTLSNIYYFMAAPTLCYEFKFPRLLRIRKHFLIKRTVELIFLSFLIAALVQQWVVPTVRNSMKPLSEMEYSRCLERLLKLAIPNHLIWLLFFYTFFHSFLNLIAELLRFADREFYRDFWNAETIGYFWKSWNIPVHRFAVRHIYSPMM---RNNFSKMSAFFVVFFVSAFFHEYLVSVPLK-----IFRLWS--YYGMMGQIPLSIITDKVVRG-GRTGNIIVWLSLIVGQPLAILMYGHDWY 482
BLAST of O-acyltransferase vs. Ensembl Celegans
Match: mboa-2 (O-acyltransferase [Source:UniProtKB/TrEMBL;Acc:F1LIN4]) HSP 1 Score: 85.8853 bits (211), Expect = 1.967e-17 Identity = 67/260 (25.77%), Postives = 133/260 (51.15%), Query Frame = 1 Query: 823 IRENVAKELKSNELIETINFSRYLYFLFAPTLIYRDSYPKNPTIRWSYVVSNFAQVIFCIVYMYYIFARFCVVYFQNFNSIHVTMQ--QLVLSVFGCMLPATLVFFICFFCFLHSWLNAFAEMLQFGDRLFYKEWWNSTTFSNYYRTWNVVVHDWLYTYVYRDILLLCRFN-NRAAAMTIVFLFSAVFHEYVLIVMFRFFYPVLFVLFSGVGFGMM-----------FIKGRARIWNIGFWVAMFTGNGIIMCLYSMEWY 1560 +++ ++ + + + S YF+ APTL Y +P+ IR +++ ++IF + + ++ V +N M+ + + + +P L++ + F+ F HS+LN AE+L+F DR FY+++WN+ T ++++WN+ VH + ++Y ++ R N ++ +A +VF SA FHEY++ V + +F L+S +GMM ++G R NI W+++ G + + +Y +WY Sbjct: 234 LKDELSMHQMAAQYPANLTLSNIYYFMAAPTLCYEFKFPRLLRIRKHFLIKRTVELIFLSFLIAALVQQWVVPTVRNSMKPLSEMEYSRCLERLLKLAIPNHLIWLLFFYTFFHSFLNLIAELLRFADREFYRDFWNAETIGYFWKSWNIPVHRFAVRHIYSPMM---RNNFSKMSAFFVVFFVSAFFHEYLVSVPLK-----IFRLWS--YYGMMGQIPLSIITDKVVRG-GRTGNIIVWLSLIVGQPLAILMYGHDWY 482
BLAST of O-acyltransferase vs. Ensembl Fly
Match: CG8112 (gene:FBgn0037612 transcript:FBtr0305337) HSP 1 Score: 275.018 bits (702), Expect = 1.578e-84 Identity = 188/555 (33.87%), Postives = 283/555 (50.99%), Query Frame = 1 Query: 85 EIRNRRINETGIVKDYENQFSDDNATKFFQKINWK--------EKTEKKQKEFIDNVEKDMKLMF-----GKLKEVIIEEYDEMTNETLDSP--KKLCNINLKHDMLPEKQFQNRESVLTNLLNISHIRTVYHMFVAILIIFSLNTMLTDLIEKGGI---IHTYH--LEWVFWAFGGIGDVILLWLSMKSFTIFVYPCFLSWLYVRRMKILPISCVNKIY----LVVYILTQISFVVIPLYFMCLIDLPPCSSAIVVLENIRLAMKIHAFIRENVAKELKS-------------NELIETINFSRYLYFLFAPTLIYRDSYPKNPTIRWSYVVSNFAQVIFCIVYMY-YIFARFCVVYFQNFNSIHVTMQQLVLSVFGCMLPATLVFFICFFCFLHSWLNAFAEMLQFGDRLFYKEWWNSTTFSNYYRTWNVVVHDWLYTYVYRDILLLCRFNNRAAAMTIVFLFSAVFHEYVLIVMFRFFYPVLFVLFSGVGFGMMFIKGRAR--IWNIGFWVAMFTGNGIIMCLYSMEWYARRNCPIYFSTFVDLLVPRSWFC 1629 E R+ + G V+D +F T F Q+++ + E + EF + D K + + + + + N T P + + + LPEK F RES LT LL + H+RT+YH+F IL++F LN + D G + T+ L + W G +WL F + +Y F W VR K+ P S + + + L++YI +Q+ F + +LP S+ I++LE+ RL MK+HAF+R N + L +E S Y YFLFAPTLIYRDSYP+ IRW + ++ +V+ I ++Y +I R +F + + QL+L +FG MLP+ ++F F+ LHSWLN +E+L+FGDR+FYK+WW S T+ YYR WNVVVHDWLY YVY+D+ ++ AA VF+ SAV HE VL + F+PV+F F VG ++F+ A + NI W ++ GN ++ LY+ME YA +NC + ++ L+P W C Sbjct: 12 EETQPRLPDLGFVRDKLQKFQSKMLTDFEQRLSCMVEDVLQDLRQRELRAHEFPNFERSDRKSTWHNRVTSQAPADVSDSTNGHANGTHPRPPIQSETSARKQRRQLPEKVFVARESYLTALLQVEHMRTIYHIFYIILVMFLLNVICYDYFVDGRFDLGLGTFRGGLRRLHWVMG-------VWLLEHVFVLALYFAFRGWALVRH-KLKPHSSLQRFWSHSCLILYISSQLVFCFVSTSLCLKFNLPFVSACILLLESTRLLMKMHAFVRYNAERVLNGKAKKEDAEEEKEGSERPFVPPLSCYTYFLFAPTLIYRDSYPRTSHIRWKFALNRLLEVV-AIAFLYAFIHERHIHEHFGQYGLEPMGPSQLILKLFGMMLPSAVIFLCGFYLILHSWLNFTSELLRFGDRMFYKDWWTSHTYDGYYRNWNVVVHDWLYEYVYKDMYTHVFRGSKVAASLAVFMISAVVHEQVLGFALQMFFPVMFFFFGVVGVALVFLMRSAPKVMGNIFLWFSLILGNATLISLYAMEHYALKNCNLSNESWTYRLLPAVWRC 557
BLAST of O-acyltransferase vs. Ensembl Fly
Match: mdy (gene:FBgn0004797 transcript:FBtr0080916) HSP 1 Score: 107.842 bits (268), Expect = 2.477e-24 Identity = 62/189 (32.80%), Postives = 104/189 (55.03%), Query Frame = 1 Query: 868 ETINFSRYLYFLFAPTLIYRDSYPKNPTIRWSYVVSNFAQVIFCIVYMYYIFA-------RFCVVYFQNFNSIHVTMQQLVLSVFGCMLPATLVFFICFFCFLHSWLNAFAEMLQFGDRLFYKEWWNSTTFSNYYRTWNVVVHDWLYTYVYRDILLLCRFNNRAAAMTIVFLFSAVFHEYVLIVMFRFF 1413 + + + LYFL APTL Y ++P+ +R +++ +V+ + + +F R ++ F N + T + L L+ LP L + F+ HS+LNA E+L F DR FY +WWN+ ++RTWN+ VH W ++Y ++ + +++R A+ TIVFLFSAVFHEY++ V + + Sbjct: 315 DNLTYKDLLYFLCAPTLCYELNFPRTSRVRKRFLLKRLLEVVIGVNVVMALFQQWIIPSVRNSLIPFSNMDVALATERLLKLA-----LPNHLCWLCFFYLMFHSFLNAVGELLNFADRNFYCDWWNANNIDTFWRTWNMPVHRWCVRHLYIPVVQMG-YSSRQAS-TIVFLFSAVFHEYLVSVPLQIY 496
BLAST of O-acyltransferase vs. Ensembl Fly
Match: mdy (gene:FBgn0004797 transcript:FBtr0080915) HSP 1 Score: 107.842 bits (268), Expect = 2.477e-24 Identity = 62/189 (32.80%), Postives = 104/189 (55.03%), Query Frame = 1 Query: 868 ETINFSRYLYFLFAPTLIYRDSYPKNPTIRWSYVVSNFAQVIFCIVYMYYIFA-------RFCVVYFQNFNSIHVTMQQLVLSVFGCMLPATLVFFICFFCFLHSWLNAFAEMLQFGDRLFYKEWWNSTTFSNYYRTWNVVVHDWLYTYVYRDILLLCRFNNRAAAMTIVFLFSAVFHEYVLIVMFRFF 1413 + + + LYFL APTL Y ++P+ +R +++ +V+ + + +F R ++ F N + T + L L+ LP L + F+ HS+LNA E+L F DR FY +WWN+ ++RTWN+ VH W ++Y ++ + +++R A+ TIVFLFSAVFHEY++ V + + Sbjct: 315 DNLTYKDLLYFLCAPTLCYELNFPRTSRVRKRFLLKRLLEVVIGVNVVMALFQQWIIPSVRNSLIPFSNMDVALATERLLKLA-----LPNHLCWLCFFYLMFHSFLNAVGELLNFADRNFYCDWWNANNIDTFWRTWNMPVHRWCVRHLYIPVVQMG-YSSRQAS-TIVFLFSAVFHEYLVSVPLQIY 496
BLAST of O-acyltransferase vs. Ensembl Fly
Match: mdy (gene:FBgn0004797 transcript:FBtr0080917) HSP 1 Score: 107.842 bits (268), Expect = 2.477e-24 Identity = 62/189 (32.80%), Postives = 104/189 (55.03%), Query Frame = 1 Query: 868 ETINFSRYLYFLFAPTLIYRDSYPKNPTIRWSYVVSNFAQVIFCIVYMYYIFA-------RFCVVYFQNFNSIHVTMQQLVLSVFGCMLPATLVFFICFFCFLHSWLNAFAEMLQFGDRLFYKEWWNSTTFSNYYRTWNVVVHDWLYTYVYRDILLLCRFNNRAAAMTIVFLFSAVFHEYVLIVMFRFF 1413 + + + LYFL APTL Y ++P+ +R +++ +V+ + + +F R ++ F N + T + L L+ LP L + F+ HS+LNA E+L F DR FY +WWN+ ++RTWN+ VH W ++Y ++ + +++R A+ TIVFLFSAVFHEY++ V + + Sbjct: 315 DNLTYKDLLYFLCAPTLCYELNFPRTSRVRKRFLLKRLLEVVIGVNVVMALFQQWIIPSVRNSLIPFSNMDVALATERLLKLA-----LPNHLCWLCFFYLMFHSFLNAVGELLNFADRNFYCDWWNANNIDTFWRTWNMPVHRWCVRHLYIPVVQMG-YSSRQAS-TIVFLFSAVFHEYLVSVPLQIY 496
BLAST of O-acyltransferase vs. Ensembl Fly
Match: mdy (gene:FBgn0004797 transcript:FBtr0347182) HSP 1 Score: 107.842 bits (268), Expect = 2.477e-24 Identity = 62/189 (32.80%), Postives = 104/189 (55.03%), Query Frame = 1 Query: 868 ETINFSRYLYFLFAPTLIYRDSYPKNPTIRWSYVVSNFAQVIFCIVYMYYIFA-------RFCVVYFQNFNSIHVTMQQLVLSVFGCMLPATLVFFICFFCFLHSWLNAFAEMLQFGDRLFYKEWWNSTTFSNYYRTWNVVVHDWLYTYVYRDILLLCRFNNRAAAMTIVFLFSAVFHEYVLIVMFRFF 1413 + + + LYFL APTL Y ++P+ +R +++ +V+ + + +F R ++ F N + T + L L+ LP L + F+ HS+LNA E+L F DR FY +WWN+ ++RTWN+ VH W ++Y ++ + +++R A+ TIVFLFSAVFHEY++ V + + Sbjct: 315 DNLTYKDLLYFLCAPTLCYELNFPRTSRVRKRFLLKRLLEVVIGVNVVMALFQQWIIPSVRNSLIPFSNMDVALATERLLKLA-----LPNHLCWLCFFYLMFHSFLNAVGELLNFADRNFYCDWWNANNIDTFWRTWNMPVHRWCVRHLYIPVVQMG-YSSRQAS-TIVFLFSAVFHEYLVSVPLQIY 496
BLAST of O-acyltransferase vs. Ensembl Zebrafish
Match: soat1 (sterol O-acyltransferase 1 [Source:ZFIN;Acc:ZDB-GENE-081105-177]) HSP 1 Score: 400.208 bits (1027), Expect = 8.969e-133 Identity = 218/527 (41.37%), Postives = 317/527 (60.15%), Query Frame = 1 Query: 106 NETGIVKDYEN-QFSDDNATKFFQKINWKEKTEKKQKEFIDNVEKDMKLMFGKLKEVIIEEYDEMTNE------TLDSPKKLCNINLKHDMLPEKQFQNRESVLTNLLNISHIRTVYHMFVAILIIFSLNTMLTDLIEKGGIIHTYHLEWVFWAFGGIGDVILLWLSM-KSFTIFVYPCFLSW--LYVRRMKILPISCVNKIYLVVYILTQISFVVIPLYFMCLIDLPPCSSAIVVLENIRLAMKIHAFIRENVAK----ELKSNELIETINFSRYLYFLFAPTLIYRDSYPKNPTIRWSYVVSNFAQVIFCIVYMYYIFARFCVVYFQNFNSIHVTMQQLVLSVFGCMLPATLVFFICFFCFLHSWLNAFAEMLQFGDRLFYKEWWNSTTFSNYYRTWNVVVHDWLYTYVYRDILLLCRFNNRAAAMTIVFLFSAVFHEYVLIVMFRFFYPVLFVLFSGVGFGMMF-----IKGRARIWNIGFWVAMFTGNGIIMCLYSMEWYARRNCPIYFSTFVDLLVPRSWFC 1629 ++ G +D E S + + Q I+ K + +KK + ++ + + + +IEE + + L +K N + KQF R S+L +L ++HIRT+YHMF+A+LI+F +T++ D I++G ++ + L + +AFG V++ W+ M S + Y + W +Y L + + L++Y + F +P Y + LPP S I++LE +RL MK H+FIRENV + + + L+ F++Y+YFLFAPTLIY+D+YP+NP IRW YV + F+QV+ + Y YYIF R C+ F+N + + +VL VF +LP LV F+ FF FLH WLNAFAEML+FGDR+FYK+WWNST+++NYYRTWNVVVHDWLY YVYRD L + + RA AM +VF SAV HEYVL + F FFYPV+F LF + FGM+F + + IWN+ W ++F G G+++CLYS EWYA+R CPI + +DLL PRSW C Sbjct: 23 DKDGPERDAEEFPLSSNGKVEVEQIISAKLQLKKKAEHLKADLMRQFDAQVNEFMDSLIEESASLGSSHVSTVFPLSDKEKSKLRNAQPSQGQSKQFVIRRSLLDDLFEVNHIRTIYHMFIALLILFIFSTLVVDFIDEGRLVLEFDL--LVYAFGQFPLVVVTWMCMFLSTLVVPYVLLVVWAGIYSSSQHRLLWTVLAGSILLIYQGLGLGF--LPTYVVLKNGLPPASCFILILEQVRLMMKSHSFIRENVPRVRSLDRNKSNLVAVPQFTQYIYFLFAPTLIYKDNYPRNPCIRWGYVATKFSQVLGSLFYAYYIFVRLCIPQFRNISMQLFDPRAMVLCVFNSILPGVLVLFLAFFAFLHCWLNAFAEMLRFGDRMFYKDWWNSTSYANYYRTWNVVVHDWLYYYVYRDFLWMTQKRFRAVAMLVVFTVSAVVHEYVLAICFGFFYPVMFCLF--MCFGMVFNFVLHDRRKGPIWNVIMWTSLFLGQGVMICLYSQEWYAQRYCPIEEPSLIDLLKPRSWTC 543
BLAST of O-acyltransferase vs. Ensembl Zebrafish
Match: soat1 (sterol O-acyltransferase 1 [Source:ZFIN;Acc:ZDB-GENE-081105-177]) HSP 1 Score: 400.208 bits (1027), Expect = 8.969e-133 Identity = 218/527 (41.37%), Postives = 317/527 (60.15%), Query Frame = 1 Query: 106 NETGIVKDYEN-QFSDDNATKFFQKINWKEKTEKKQKEFIDNVEKDMKLMFGKLKEVIIEEYDEMTNE------TLDSPKKLCNINLKHDMLPEKQFQNRESVLTNLLNISHIRTVYHMFVAILIIFSLNTMLTDLIEKGGIIHTYHLEWVFWAFGGIGDVILLWLSM-KSFTIFVYPCFLSW--LYVRRMKILPISCVNKIYLVVYILTQISFVVIPLYFMCLIDLPPCSSAIVVLENIRLAMKIHAFIRENVAK----ELKSNELIETINFSRYLYFLFAPTLIYRDSYPKNPTIRWSYVVSNFAQVIFCIVYMYYIFARFCVVYFQNFNSIHVTMQQLVLSVFGCMLPATLVFFICFFCFLHSWLNAFAEMLQFGDRLFYKEWWNSTTFSNYYRTWNVVVHDWLYTYVYRDILLLCRFNNRAAAMTIVFLFSAVFHEYVLIVMFRFFYPVLFVLFSGVGFGMMF-----IKGRARIWNIGFWVAMFTGNGIIMCLYSMEWYARRNCPIYFSTFVDLLVPRSWFC 1629 ++ G +D E S + + Q I+ K + +KK + ++ + + + +IEE + + L +K N + KQF R S+L +L ++HIRT+YHMF+A+LI+F +T++ D I++G ++ + L + +AFG V++ W+ M S + Y + W +Y L + + L++Y + F +P Y + LPP S I++LE +RL MK H+FIRENV + + + L+ F++Y+YFLFAPTLIY+D+YP+NP IRW YV + F+QV+ + Y YYIF R C+ F+N + + +VL VF +LP LV F+ FF FLH WLNAFAEML+FGDR+FYK+WWNST+++NYYRTWNVVVHDWLY YVYRD L + + RA AM +VF SAV HEYVL + F FFYPV+F LF + FGM+F + + IWN+ W ++F G G+++CLYS EWYA+R CPI + +DLL PRSW C Sbjct: 23 DKDGPERDAEEFPLSSNGKVEVEQIISAKLQLKKKAEHLKADLMRQFDAQVNEFMDSLIEESASLGSSHVSTVFPLSDKEKSKLRNAQPSQGQSKQFVIRRSLLDDLFEVNHIRTIYHMFIALLILFIFSTLVVDFIDEGRLVLEFDL--LVYAFGQFPLVVVTWMCMFLSTLVVPYVLLVVWAGIYSSSQHRLLWTVLAGSILLIYQGLGLGF--LPTYVVLKNGLPPASCFILILEQVRLMMKSHSFIRENVPRVRSLDRNKSNLVAVPQFTQYIYFLFAPTLIYKDNYPRNPCIRWGYVATKFSQVLGSLFYAYYIFVRLCIPQFRNISMQLFDPRAMVLCVFNSILPGVLVLFLAFFAFLHCWLNAFAEMLRFGDRMFYKDWWNSTSYANYYRTWNVVVHDWLYYYVYRDFLWMTQKRFRAVAMLVVFTVSAVVHEYVLAICFGFFYPVMFCLF--MCFGMVFNFVLHDRRKGPIWNVIMWTSLFLGQGVMICLYSQEWYAQRYCPIEEPSLIDLLKPRSWTC 543
BLAST of O-acyltransferase vs. Ensembl Zebrafish
Match: soat2 (sterol O-acyltransferase 2 [Source:ZFIN;Acc:ZDB-GENE-061013-742]) HSP 1 Score: 367.466 bits (942), Expect = 6.111e-120 Identity = 204/523 (39.01%), Postives = 301/523 (57.55%), Query Frame = 1 Query: 133 ENQFSDDNATKFFQKINWKEKTEKKQKEFIDNVEKDMKLMFGKLKEVIIEEYDEMTNETLDSPKKLCNINL------------KHDMLPEKQFQNRESVLTNLLNISHIRTVYHMFVAILIIFSLNTMLTDLIEKGGIIHTYHLEWVFWAFGGIGDVILLWLSMKSFTIF-VYPCFLSW--LYVRRMKILPISCVNKIYLVVYILTQISFVVI-PLYFMCLIDLPPCSSAIVVLENIRLAMKIHAFIRENVAKELKS----NELIETINFSRYLYFLFAPTLIYRDSYPKNPTIRWSYVVSNFAQVIFCIVYMYYIFARFCVVYFQNFNSIHVTMQQLVLSVFGCMLPATLVFFICFFCFLHSWLNAFAEMLQFGDRLFYKEWWNSTTFSNYYRTWNVVVHDWLYTYVYRDILLLCRFNNRAAAMTIVFLFSAVFHEYVLIVMFRFFYPVLFVLFSGVGFGMMFI---KGRARIWNIGFWVAMFTGNGIIMCLYSMEWYARRNCPIYFSTFVDLLVPRSWFCQ 1632 ENQ +N + F Q N + TE ++ D++E+ + +++ + + + ++++ S + N+ +H + K F R S+L L ISHIRT+YHMF+A L +F ++T+ D I++G ++ L ++AFG + VI W M S+T+ Y W LY +CV I ++ Q+S + I P+Y + LPP S I++LE IR MK ++FIRE+ A LK+ E + S YLYFLF PTLIYR+ YP+NP IRW +V NF +V+ + Y+Y+I R C+ F+N + + + + L+L++F P L+ + F+ FLH WLNAFAEML+F DR+FYK+WWNST+F+NYYRTWN+VVHDWLY Y YRD L L + R+ A VF SA+ HEY + F FFYPV+F F+G+G F K ++ +WNI W +F G G+ +CLY +EWYA+ +CP + F DL+ PRSW C Sbjct: 53 ENQRCSENGS-FPQNENGRNITEAAHRK--DDMERLKAELIRRVQTQLNDAVERAVSDSITSLNTHSHTNMLTHTDNKTSSGDRHKLDQGKVFVARCSLLDELFEISHIRTIYHMFIAALFLFFMSTLAVDYIDQGRLV--LDLGLFYYAFGQLHVVICCWTLMFSYTLLGPYHVLRVWAGLYHNGHHR---TCVCVITAIILCAAQMSMLGIFPVYVVLHYQLPPASRFIIILEQIRFVMKSYSFIRESTAAALKNTPQKGERLWFPALSSYLYFLFCPTLIYREVYPRNPNIRWRFVGMNFLKVLASLFYLYFILERLCIPVFRNKSGLQFSTRTLILTLFHAAFPGMLMLMLGFYAFLHCWLNAFAEMLRFADRMFYKDWWNSTSFANYYRTWNIVVHDWLYYYAYRDFLWLSGYKLRSVATLSVFAVSALVHEYAFTMGFGFFYPVMFCTFAGIGVVFNFAMNDKRKSPVWNIIMWTCLFIGQGVHVCLYCLEWYAQIHCPRTGAGFWDLVTPRSWTCS 567
BLAST of O-acyltransferase vs. Ensembl Zebrafish
Match: soat2 (sterol O-acyltransferase 2 [Source:ZFIN;Acc:ZDB-GENE-061013-742]) HSP 1 Score: 271.937 bits (694), Expect = 2.960e-85 Identity = 156/390 (40.00%), Postives = 223/390 (57.18%), Query Frame = 1 Query: 175 KINWKEKTE---KKQKEFIDNVEKDMKLMFGKLKEVIIEEYDEMTNETLDSPKKLCNINLKHDMLPEKQFQNRESVLTNLLNISHIRTVYHMFVAILIIFSLNTMLTDLIEKGGIIHTYHLEWVFWAFGGIGDVILLWLSMKSFTIF-VYPCFLSW--LYVRRMKILPISCVNKIYLVVYILTQISFVVI-PLYFMCLIDLPPCSSAIVVLENIRLAMKIHAFIRENVAKELKS----NELIETINFSRYLYFLFAPTLIYRDSYPKNPTIRWSYVVSNFAQVIFCIVYMYYIFARFCVVYFQNFNSIHVTMQQLVLSVFGCMLPATLVFFICFFCFLHSWLNAFAEMLQFGDRLFYKEWWNSTTFSNYYRTWNVVVHDWLYTYVYRDIL 1311 + W+ K E + Q + D VE+ + L TN + K + + +H + K F R S+L L ISHIRT+YHMF+A L +F ++T+ D I++G ++ L ++AFG + VI W M S+T+ Y W LY +CV I ++ Q+S + I P+Y + LPP S I++LE IR MK ++FIRE+ A LK+ E + S YLYFLF PTLIYR+ YP+NP IRW +V NF +V+ + Y+Y+I R C+ F+N + + + + L+L++F P L+ + F+ FLH WLNAFAEML+F DR+FYK+WWNST+F+NYYRTWN+VVHDWLY Y YRD L Sbjct: 14 RTTWRLKAELIRRVQTQLNDAVERAVSDSITSLNT------HSHTNMLTHTDNKTSSGD-RHKLDQGKVFVARCSLLDELFEISHIRTIYHMFIAALFLFFMSTLAVDYIDQGRLV--LDLGLFYYAFGQLHVVICCWTLMFSYTLLGPYHVLRVWAGLYHNGHHR---TCVCVITAIILCAAQMSMLGIFPVYVVLHYQLPPASRFIIILEQIRFVMKSYSFIRESTAAALKNTPQKGERLWFPALSSYLYFLFCPTLIYREVYPRNPNIRWRFVGMNFLKVLASLFYLYFILERLCIPVFRNKSGLQFSTRTLILTLFHAAFPGMLMLMLGFYAFLHCWLNAFAEMLRFADRMFYKDWWNSTSFANYYRTWNIVVHDWLYYYAYRDFL 391
BLAST of O-acyltransferase vs. Ensembl Zebrafish
Match: dgat1a (diacylglycerol O-acyltransferase 1a [Source:ZFIN;Acc:ZDB-GENE-030131-4600]) HSP 1 Score: 106.301 bits (264), Expect = 7.167e-24 Identity = 73/233 (31.33%), Postives = 119/233 (51.07%), Query Frame = 1 Query: 895 YFLFAPTLIYRDSYPKNPTIRWSYVVSNFAQVIFCIVYMYYIFARFCVVYFQNFNSIHVTMQ--QLVLSVFGCMLPATLVFFICFFCFLHSWLNAFAEMLQFGDRLFYKEWWNSTTFSNYYRTWNVVVHDWLYTYVYRDILLLCRFNNRAAAMTIVFLFSAVFHEYVLIVMFRFFYPVLFVLFSGVGFGMMF------IKG---RARIWNIGFWVAMFTGNGIIMCLYSMEWY 1560 YF FAPTL Y ++P++P IR +++ +++F + M + ++ V QN M ++V + +P ++ I F+ + HS +N AE++QFGDR FY++WWNS T ++ WN+ VH W + Y+ +L+ R NR AA VF SA FHEY++ V + F F+ GMM + G R N W+++ G I + +Y ++Y Sbjct: 263 YFAFAPTLCYELNFPRSPRIRKRFLLRRLLEMLFLMQLMVGLIQQWMVPTIQNSMKPFQDMDFSRMVERMLKLAVPNHFIWLIFFYWYFHSSMNFVAEIMQFGDREFYRDWWNSETIPYFWSNWNIPVHKWCLRHFYKPMLM--RGANRLAAQIAVFFLSAFFHEYLVSVPLKMFRLWAFL-------GMMLQVPLAILVGRYLRGNYGNAAVWMSLIIGQPIAVLMYVHDYY 486
BLAST of O-acyltransferase vs. Ensembl Xenopus
Match: ythdc1 (YTH domain containing 1 [Source:Xenbase;Acc:XB-GENE-1004178]) HSP 1 Score: 410.609 bits (1054), Expect = 9.813e-137 Identity = 225/537 (41.90%), Postives = 319/537 (59.40%), Query Frame = 1 Query: 79 DGEIRNRRINETGIVKDYENQFSDDNATKFFQKINWKEKTEKKQKEFIDNVEKDMKLMFGKLKEVI---IEEYDEMTNETLDSP---KKLCNINLKHDMLPE--KQFQNRESVLTNLLNISHIRTVYHMFVAILIIFSLNTMLTDLIEKGGIIHTYHLEWVFWAFGGIGDVILLWLSMKSFTIFVYPCFLSWLYVRRMKILPISCVNKIYLVVYILT--QISFVVIPLYFMCLIDLPPCSSAIVVLENIRLAMKIHAFIRENVAK----ELKSNELIETINFSRYLYFLFAPTLIYRDSYPKNPTIRWSYVVSNFAQVIFCIVYMYYIFARFCVVYFQNFNSIHVTMQQLVLSVFGCMLPATLVFFICFFCFLHSWLNAFAEMLQFGDRLFYKEWWNSTTFSNYYRTWNVVVHDWLYTYVYRDILLLCRFNNRAAAMTIVFLFSAVFHEYVLIVMFRFFYPVLFVLFSGVGFGMMF-----IKGRARIWNIGFWVAMFTGNGIIMCLYSMEWYARRNCPIYFSTFVDLLVPRSWFCQ 1632 + E RR E + + N D +K+ ++K E + E + V+ G L E + IEE + N P +K LPE K F +R S+L L ++HIRT+YHMF+A+LI+F L+T++ D I++G ++ + L + +AFG VI WL M + F+ P L + R + + ++ + +T + +P Y + DLPP S I++LE +RL MK H+F+RENV + + + ++ ++YLYFLFAPTLIYRDSYP+NP+IRW YV + FAQV+ C+ Y YY+F R C+ F+N + +++ LVL +F +LP LV F+ FF FLH WLNAFAEML+F DR+FYK+WWNST+F+NYYRTWNVVVHDWLY Y YRD L + ++AAM VF SAV HEY L + F FFYPVLF+LF + FGM+F + + IWN+ W ++F G G+++CLYS EWYA+R+CPI F+D L PRSW C+ Sbjct: 23 EQEDVARRTEEDRVFRTVSNGLVDLEHV-ISRKMEMRKKAEHLKNELMKEVD-------GHLNEFVNNLIEESTVLENTQSFYPGNAEKDSQKARGQRALPEHGKLFVSRRSLLDELFEVNHIRTIYHMFIALLILFILSTLVVDFIDEGRLVLEFDL--LVYAFGKFPIVISTWLCM-FLSTFLIPYGLFSAWARGYRASFHRSIRSVFFGLLFMTFQMLGLGFMPTYIVLHHDLPPASRFIIILEQVRLIMKSHSFVRENVPRIFAFTKEKSSIVPVPQVTQYLYFLFAPTLIYRDSYPRNPSIRWGYVATKFAQVLGCLFYAYYVFVRLCIPLFRNISQEQFSLRVLVLCIFNSILPGVLVLFLAFFAFLHCWLNAFAEMLRFADRMFYKDWWNSTSFANYYRTWNVVVHDWLYYYAYRDFLWIFGRRFKSAAMLCVFTVSAVVHEYALGICFGFFYPVLFILF--MCFGMLFNFILHDRRKGPIWNVIMWTSLFLGQGVLICLYSQEWYAQRHCPINNPAFIDFLKPRSWTCR 546
BLAST of O-acyltransferase vs. Ensembl Xenopus
Match: lrrc32.2 (leucine rich repeat containing 32, gene 2 [Source:Xenbase;Acc:XB-GENE-6461207]) HSP 1 Score: 394.045 bits (1011), Expect = 1.620e-130 Identity = 223/530 (42.08%), Postives = 303/530 (57.17%), Query Frame = 1 Query: 79 DGEIRNRRIN--ETGIVKDYENQFSDDNATKFFQKINWKEKTEKKQKEFIDNVEKDMKLMFGKLKEVIIEEYDEMTNETLDSPKKLCNINLKHDMLPEKQ--FQNRESVLTNLLNISHIRTVYHMFVAILIIFSLNTMLTDLIEKGGIIHTYHLEWVFWAFGGIGDVILLWLSMKSFTIFV-YPCF--LSWLYVRRMKILPISC-VNKIYLVVYILTQISFVVIPLYFMCLIDLPPCSSAIVVLENIRLAMKIHAFIRENVAKEL-KSNELIETINFSRYLYFLFAPTLIYRDSYPKNPTIRWSYVVSNFAQVIFCIVYMYYIFARFCVVYFQNFNSIHVTMQQLVLSVFGCMLPATLVFFICFFCFLHSWLNAFAEMLQFGDRLFYKEWWNSTTFSNYYRTWNVVVHDWLYTYVYRDILLLCRFNNRAAAMTIVFLFSAVFHEYVLIVMFRFFYPVLFVLFS--GVGFG-MMFIKGRARIWNIGFWVAMFTGNGIIMCLYSMEWYARRNCPIYFSTFVDLLVPRSWFCQ 1632 + +R R+ + + SD N I WK E + E ++ + +K + K + Y L S K N + EKQ F +R S+L +L+ + H RT+YHMFVA+L +F +NT D+I++G + L +F+ FG + V+ WL + +T+ V Y L LY L +S + + LV I V+P+Y + LPP SS IV+LE +R MK ++F+RE V L K + I+ FS YLYFLF PTLIYR+SYP+ P IRW++V NFAQ + C+ + YY+ C+ F N + + + LVLS+F LP T V + FF FLH WLNAFAEML+F DR+FY++WWNST+FSNYYRTWNVVVHDWLY YVYRD+L LC RA M VFL SA HEYV + R+FYPVLF LF+ GV F MM K ++ +WN+ W +F G GI +CLYS EWYA+ +CP+ TF L+ PRSW C+ Sbjct: 9 EDSLRQRKNHHPKEAACNGKAGGLSDGNGINGL--IEWKRHMEGVKAELVEEMSCHLKDLLDKAVAETMHSYKRKIASALSSKKDHVNNKRHQGSISEKQKVFMHRASLLDDLMEVEHFRTIYHMFVAVLCVFVINTTAVDIIDQGRLFLDLDL--LFYTFGQLSTVVWTWLCLFMYTLLVPYRALHVLGSLYPESSHPLLLSAFIGGLLLVCQIFV---LGVLPIYVVTQYKLPPASSFIVILEQVRFLMKSYSFLRECVPLLLRKEKKDIQLPKFSSYLYFLFCPTLIYRESYPRTPYIRWNFVAKNFAQFLGCLFFGYYVLFTLCIPVFTNMSKQPFSNKTLVLSIFHATLPGTFVLLLSFFAFLHCWLNAFAEMLRFADRMFYEDWWNSTSFSNYYRTWNVVVHDWLYYYVYRDLLSLCNQRYRAGIMLTVFLLSASVHEYVFTLSLRYFYPVLFCLFAIFGVLFNFMMNDKRKSPVWNVMVWTFLFIGQGIQLCLYSQEWYAQIHCPLTEKTFWGLVTPRSWSCR 531
BLAST of O-acyltransferase vs. Ensembl Xenopus
Match: ythdc1 (YTH domain containing 1 [Source:Xenbase;Acc:XB-GENE-1004178]) HSP 1 Score: 382.489 bits (981), Expect = 8.784e-126 Identity = 218/538 (40.52%), Postives = 309/538 (57.43%), Query Frame = 1 Query: 79 DGEIRNRRINETGIVKDYENQFSDDNATKFFQKINWKEKTEKKQKEFIDNVEKDMKLMFGKLKEVI---IEEYDEMTNETLDSP---KKLCNINLKHDMLPE--KQFQNRESVLTNLLNISHIRTVYHM-FVAILIIFSLNTMLTDLIEKGGIIHTYHLEWVFWAFGGIGDVILLWLSMKSFTIFVYPCFLSWLYVRRMKILPISCVNKIYLVVYILT--QISFVVIPLYFMCLIDLPPCSSAIVVLENIRLAMKIHAFIRENVAK----ELKSNELIETINFSRYLYFLFAPTLIYRDSYPKNPTIRWSYVVSNFAQVIFCIVYMYYIFARFCVVYFQNFNSIHVTMQQLVLSVFGCMLPATLVFFICFFCFLHSWLNAFAEMLQFGDRLFYKEWWNSTTFSNYYRTWNVVVHDWLYTYVYRDILLLCRFNNRAAAMTIVFLFSAVFHEYVLIVMFRFFYPVLFVLFSGVGFGMMF-----IKGRARIWNIGFWVAMFTGNGIIMCLYSMEWYARRNCPIYFSTFVDLLVPRSWFCQ 1632 + E RR E + + N D +K+ ++K E + E + V+ G L E + IEE + N P +K LPE K F +R S+L L ++HIRT+YHM + F L ++ I++ ++ + L + +AFG VI WL M + F+ P L + R + + ++ + +T + +P Y + DLPP S I++LE +RL MK H+F+RENV + + + ++ ++YLYFLFAPTLIYRDSYP+NP+IRW YV + FAQV+ C+ Y YY+F R C+ F+N + +++ LVL +F +LP LV F+ FF FLH WLNAFAEML+F DR+FYK+WWNST+F+NYYRTWNVVVHDWLY Y YRD L + ++AAM VF SAV HEY L + F FFYPVLF+LF + FGM+F + + IWN+ W ++F G G+++CLYS EWYA+R+CPI F+D L PRSW C+ Sbjct: 23 EQEDVARRTEEDRVFRTVSNGLVDLEHV-ISRKMEMRKKAEHLKNELMKEVD-------GHLNEFVNNLIEESTVLENTQSFYPGNAEKDSQKARGQRALPEHGKLFVSRRSLLDELFEVNHIRTIYHMPLFFFVFFFKLLLKISQYIQRYRLVLEFDL--LVYAFGKFPIVISTWLCM-FLSTFLIPYGLFSAWARGYRASFHRSIRSVFFGLLFMTFQMLGLGFMPTYIVLHHDLPPASRFIIILEQVRLIMKSHSFVRENVPRIFAFTKEKSSIVPVPQVTQYLYFLFAPTLIYRDSYPRNPSIRWGYVATKFAQVLGCLFYAYYVFVRLCIPLFRNISQEQFSLRVLVLCIFNSILPGVLVLFLAFFAFLHCWLNAFAEMLRFADRMFYKDWWNSTSFANYYRTWNVVVHDWLYYYAYRDFLWIFGRRFKSAAMLCVFTVSAVVHEYALGICFGFFYPVLFILF--MCFGMLFNFILHDRRKGPIWNVIMWTSLFLGQGVLICLYSQEWYAQRHCPINNPAFIDFLKPRSWTCR 547
BLAST of O-acyltransferase vs. Ensembl Xenopus
Match: ythdc1 (YTH domain containing 1 [Source:Xenbase;Acc:XB-GENE-1004178]) HSP 1 Score: 371.703 bits (953), Expect = 5.174e-123 Identity = 196/446 (43.95%), Postives = 281/446 (63.00%), Query Frame = 1 Query: 295 MTNETLDSPKKLCNINLKHDMLPEKQFQNRES-----VLTNLLNISHIRTVYHMFVAILIIFSLNTMLTDLIEKGGIIHTYHLEWVFWAFGGIGDVILLWLSMKSFTIFV-YPCFLSWLYVRRMKILPISCVNKIYLVVYILT--QISFVVIPLYFMCLIDLPPCSSAIVVLENIRLAMKIHAFIRENVAK----ELKSNELIETINFSRYLYFLFAPTLIYRDSYPKNPTIRWSYVVSNFAQVIFCIVYMYYIFARFCVVYFQNFNSIHVTMQQLVLSVFGCMLPATLVFFICFFCFLHSWLNAFAEMLQFGDRLFYKEWWNSTTFSNYYRTWNVVVHDWLYTYVYRDILLLCRFNNRAAAMTIVFLFSAVFHEYVLIVMFRFFYPVLFVLFSGVGFGMMF-----IKGRARIWNIGFWVAMFTGNGIIMCLYSMEWYARRNCPI 1581 +T E + K+L + H Q + + + + + L ++HIRT+YHMF+A+LI+F L+T++ D I++G ++ + L + +AFG VI WL M T + Y F +W R + + ++ + +T + +P Y + DLPP S I++LE +RL MK H+F+RENV + + + ++ ++YLYFLFAPTLIYRDSYP+NP+IRW YV + FAQV+ C+ Y YY+F R C+ F+N + +++ LVL +F +LP LV F+ FF FLH WLNAFAEML+F DR+FYK+WWNST+F+NYYRTWNVVVHDWLY Y YRD L + ++AAM VF SAV HEY L + F FFYPVLF+LF + FGM+F + + IWN+ W ++F G G+++CLYS EWYA+R+CPI Sbjct: 3 LTREPQSNVKRLGEQHKHHKSSWRCQIRCQMADTVSFLHSELFEVNHIRTIYHMFIALLILFILSTLVVDFIDEGRLVLEFDL--LVYAFGKFPIVISTWLCMFLSTFLIPYGLFSAW--ARGYRASFHRSIRSVFFGLLFMTFQMLGLGFMPTYIVLHHDLPPASRFIIILEQVRLIMKSHSFVRENVPRIFAFTKEKSSIVPVPQVTQYLYFLFAPTLIYRDSYPRNPSIRWGYVATKFAQVLGCLFYAYYVFVRLCIPLFRNISQEQFSLRVLVLCIFNSILPGVLVLFLAFFAFLHCWLNAFAEMLRFADRMFYKDWWNSTSFANYYRTWNVVVHDWLYYYAYRDFLWIFGRRFKSAAMLCVFTVSAVVHEYALGICFGFFYPVLFILF--MCFGMLFNFILHDRRKGPIWNVIMWTSLFLGQGVLICLYSQEWYAQRHCPI 442
BLAST of O-acyltransferase vs. Ensembl Xenopus
Match: ythdc1 (YTH domain containing 1 [Source:Xenbase;Acc:XB-GENE-1004178]) HSP 1 Score: 372.089 bits (954), Expect = 5.564e-123 Identity = 194/418 (46.41%), Postives = 272/418 (65.07%), Query Frame = 1 Query: 367 KQFQNRESVL-TNLLNISHIRTVYHMFVAILIIFSLNTMLTDLIEKGGIIHTYHLEWVFWAFGGIGDVILLWLSMKSFTIFV-YPCFLSWLYVRRMKILPISCVNKIYLVVYILT--QISFVVIPLYFMCLIDLPPCSSAIVVLENIRLAMKIHAFIRENVAK----ELKSNELIETINFSRYLYFLFAPTLIYRDSYPKNPTIRWSYVVSNFAQVIFCIVYMYYIFARFCVVYFQNFNSIHVTMQQLVLSVFGCMLPATLVFFICFFCFLHSWLNAFAEMLQFGDRLFYKEWWNSTTFSNYYRTWNVVVHDWLYTYVYRDILLLCRFNNRAAAMTIVFLFSAVFHEYVLIVMFRFFYPVLFVLFSGVGFGMMF-----IKGRARIWNIGFWVAMFTGNGIIMCLYSMEWYARRNCPI 1581 +Q Q S L + L ++HIRT+YHMF+A+LI+F L+T++ D I++G ++ + L + +AFG VI WL M T + Y F +W R + + ++ + +T + +P Y + DLPP S I++LE +RL MK H+F+RENV + + + ++ ++YLYFLFAPTLIYRDSYP+NP+IRW YV + FAQV+ C+ Y YY+F R C+ F+N + +++ LVL +F +LP LV F+ FF FLH WLNAFAEML+F DR+FYK+WWNST+F+NYYRTWNVVVHDWLY Y YRD L + ++AAM VF SAV HEY L + F FFYPVLF+LF + FGM+F + + IWN+ W ++F G G+++CLYS EWYA+R+CPI Sbjct: 40 EQHQGVISFLHSELFEVNHIRTIYHMFIALLILFILSTLVVDFIDEGRLVLEFDL--LVYAFGKFPIVISTWLCMFLSTFLIPYGLFSAW--ARGYRASFHRSIRSVFFGLLFMTFQMLGLGFMPTYIVLHHDLPPASRFIIILEQVRLIMKSHSFVRENVPRIFAFTKEKSSIVPVPQVTQYLYFLFAPTLIYRDSYPRNPSIRWGYVATKFAQVLGCLFYAYYVFVRLCIPLFRNISQEQFSLRVLVLCIFNSILPGVLVLFLAFFAFLHCWLNAFAEMLRFADRMFYKDWWNSTSFANYYRTWNVVVHDWLYYYAYRDFLWIFGRRFKSAAMLCVFTVSAVVHEYALGICFGFFYPVLFILF--MCFGMLFNFILHDRRKGPIWNVIMWTSLFLGQGVLICLYSQEWYAQRHCPI 451
BLAST of O-acyltransferase vs. Ensembl Mouse
Match: Soat1 (sterol O-acyltransferase 1 [Source:MGI Symbol;Acc:MGI:104665]) HSP 1 Score: 402.134 bits (1032), Expect = 1.189e-133 Identity = 235/552 (42.57%), Postives = 323/552 (58.51%), Query Frame = 1 Query: 85 EIRNRRINETGIVKDYENQFSDDNATKFFQKINWKEKTEKK---QKEFIDNVEKDMKLMFGKLKEV----------IIEEYDEMTN--------ETLDSPKKLCNINLKHDMLPEKQ---FQNRESVLTNLLNISHIRTVYHMFVAILIIFSLNTMLTDLIEKGGIIHTYHLEWVFWAFGGIGDVILLWLSMKSFTIFV-YPCFLSWL--YVRRMKILPISCVNKIYLVVYILTQISFVVIPLYFMCLIDLPPCSSAIVVLENIRLAMKIHAFIRENV------AKELKSNELIETINFSRYLYFLFAPTLIYRDSYPKNPTIRWSYVVSNFAQVIFCIVYMYYIFARFCVVYFQNFNSIHVTMQQLVLSVFGCMLPATLVFFICFFCFLHSWLNAFAEMLQFGDRLFYKEWWNSTTFSNYYRTWNVVVHDWLYTYVYRDILLLCRFNNRAAAMTIVFLFSAVFHEYVLIVMFRFFYPVLFVLFSGVGFGMMFIKGRAR---IWNIGFWVAMFTGNGIIMCLYSMEWYARRNCPIYFSTFVDLLVPRSWFCQ 1632 +RNR + K EN D+ F T K+ +K + +++K +F +KEV +IE+ + N L+ KK N K P +Q F +R+S+L L + HIRT+YHMF+A+LI+F L+T++ D I++G ++ ++L + +AFG VI W +M T+ + Y F W Y + L S V+ + +V+ L + FV P Y + LPP S I++LE IRL MK H+F+REN+ AKE S + + T+N +YLYFLFAPTLIYRD+YP+ PT+RW YV F QV C+ Y+YYIF R C F+N + + LVL VF +LP L+ F+ FF FLH WLNAFAEML+FGDR+FYK+WWNST++SNYYRTWNVVVHDWLY YVY+D+L ++AAM VF SAV HEY L + +FYPVLFVLF G FI +R IWNI W ++F G G+I+C YS EWYAR++CP+ TF+D + PR+W C+ Sbjct: 2 SLRNR------LSKSGENPEQDEAQKNFMDTYRNGHITMKQLIAKKRLLAAEAEELKPLF--MKEVGCHFDDFVTNLIEKSASLDNGGCALTTFSILEEMKK--NHRAKDLRAPPEQGKIFISRQSLLDELFEVDHIRTIYHMFIALLILFVLSTIVVDYIDEGRLVLEFNL--LAYAFGKFPTVIWTWWAMFLSTLSIPYFLFQRWAHGYSKSSHPLIYSLVHGLLFLVFQLGVLGFV--PTYVVLAYTLPPASRFILILEQIRLIMKAHSFVRENIPRVLNAAKEKSSKDPLPTVN--QYLYFLFAPTLIYRDNYPRTPTVRWGYVAMQFLQVFGCLFYVYYIFERLCAPLFRNIKQEPFSARVLVLCVFNSILPGVLILFLSFFAFLHCWLNAFAEMLRFGDRMFYKDWWNSTSYSNYYRTWNVVVHDWLYYYVYKDLLWFFSKRFKSAAMLAVFALSAVVHEYALAICLSYFYPVLFVLFMFFGMAFNFIVNDSRKRPIWNIMVWASLFLGYGLILCFYSQEWYARQHCPLKNPTFLDYVRPRTWTCR 537
BLAST of O-acyltransferase vs. Ensembl Mouse
Match: Soat1 (sterol O-acyltransferase 1 [Source:MGI Symbol;Acc:MGI:104665]) HSP 1 Score: 402.134 bits (1032), Expect = 1.189e-133 Identity = 235/552 (42.57%), Postives = 323/552 (58.51%), Query Frame = 1 Query: 85 EIRNRRINETGIVKDYENQFSDDNATKFFQKINWKEKTEKK---QKEFIDNVEKDMKLMFGKLKEV----------IIEEYDEMTN--------ETLDSPKKLCNINLKHDMLPEKQ---FQNRESVLTNLLNISHIRTVYHMFVAILIIFSLNTMLTDLIEKGGIIHTYHLEWVFWAFGGIGDVILLWLSMKSFTIFV-YPCFLSWL--YVRRMKILPISCVNKIYLVVYILTQISFVVIPLYFMCLIDLPPCSSAIVVLENIRLAMKIHAFIRENV------AKELKSNELIETINFSRYLYFLFAPTLIYRDSYPKNPTIRWSYVVSNFAQVIFCIVYMYYIFARFCVVYFQNFNSIHVTMQQLVLSVFGCMLPATLVFFICFFCFLHSWLNAFAEMLQFGDRLFYKEWWNSTTFSNYYRTWNVVVHDWLYTYVYRDILLLCRFNNRAAAMTIVFLFSAVFHEYVLIVMFRFFYPVLFVLFSGVGFGMMFIKGRAR---IWNIGFWVAMFTGNGIIMCLYSMEWYARRNCPIYFSTFVDLLVPRSWFCQ 1632 +RNR + K EN D+ F T K+ +K + +++K +F +KEV +IE+ + N L+ KK N K P +Q F +R+S+L L + HIRT+YHMF+A+LI+F L+T++ D I++G ++ ++L + +AFG VI W +M T+ + Y F W Y + L S V+ + +V+ L + FV P Y + LPP S I++LE IRL MK H+F+REN+ AKE S + + T+N +YLYFLFAPTLIYRD+YP+ PT+RW YV F QV C+ Y+YYIF R C F+N + + LVL VF +LP L+ F+ FF FLH WLNAFAEML+FGDR+FYK+WWNST++SNYYRTWNVVVHDWLY YVY+D+L ++AAM VF SAV HEY L + +FYPVLFVLF G FI +R IWNI W ++F G G+I+C YS EWYAR++CP+ TF+D + PR+W C+ Sbjct: 2 SLRNR------LSKSGENPEQDEAQKNFMDTYRNGHITMKQLIAKKRLLAAEAEELKPLF--MKEVGCHFDDFVTNLIEKSASLDNGGCALTTFSILEEMKK--NHRAKDLRAPPEQGKIFISRQSLLDELFEVDHIRTIYHMFIALLILFVLSTIVVDYIDEGRLVLEFNL--LAYAFGKFPTVIWTWWAMFLSTLSIPYFLFQRWAHGYSKSSHPLIYSLVHGLLFLVFQLGVLGFV--PTYVVLAYTLPPASRFILILEQIRLIMKAHSFVRENIPRVLNAAKEKSSKDPLPTVN--QYLYFLFAPTLIYRDNYPRTPTVRWGYVAMQFLQVFGCLFYVYYIFERLCAPLFRNIKQEPFSARVLVLCVFNSILPGVLILFLSFFAFLHCWLNAFAEMLRFGDRMFYKDWWNSTSYSNYYRTWNVVVHDWLYYYVYKDLLWFFSKRFKSAAMLAVFALSAVVHEYALAICLSYFYPVLFVLFMFFGMAFNFIVNDSRKRPIWNIMVWASLFLGYGLILCFYSQEWYARQHCPLKNPTFLDYVRPRTWTCR 537
BLAST of O-acyltransferase vs. Ensembl Mouse
Match: Soat2 (sterol O-acyltransferase 2 [Source:MGI Symbol;Acc:MGI:1332226]) HSP 1 Score: 362.073 bits (928), Expect = 2.489e-118 Identity = 194/526 (36.88%), Postives = 295/526 (56.08%), Query Frame = 1 Query: 97 RRINETGIVKDYENQFSDDNATKFFQK--INWKEKTEKKQKEFIDNVEKDMKLMFGKLKEVIIEEYDE----MTNETLDSPKKLCNINLKHDMLPEKQ--FQNRESVLTNLLNISHIRTVYHMFVAILIIFSLNTMLTDLIEKGGIIHTYHLEWVFWAFGGIGDVILLWLSMKSFTIFVYPCFLSWLYVRRMKILPISCVNKIYLVVYILTQISFVVIPLYFMCLIDLPPCSSAIVVLENIRLAMKIHAFIRENVAK--ELKSNELIETINFSRYLYFLFAPTLIYRDSYPKNPTIRWSYVVSNFAQVIFCIVYMYYIFARFCVVYFQNFNSIHVTMQQLVLSVFGCMLPATLVFFICFFCFLHSWLNAFAEMLQFGDRLFYKEWWNSTTFSNYYRTWNVVVHDWLYTYVYRDILLLCRFNNRAAAMTIVFLFSAVFHEYVLIVMFRFFYPV---LFVLFSGVGFGMMFIKGRARIWNIGFWVAMFTGNGIIMCLYSMEWYARRNCPIYFSTFVDLLVPRSWFCQA 1635 RR G ++ + + NA + W E + +F++ ++++ + + ++ Y + + + DS K ++ P K+ F R+S++ L+ + H RT+YHMF+A L + ++T+ D I++G ++ + L + ++FG + ++ W+ M T+ V P WL+ R + V+ + V+P++ +LPP S ++V E +RL MK ++F+RE V ++ + I +FS YLYFLF PTLIYR++YP+ P+IRW+YV NFAQV+ C++Y +I R CV F N + + + L+LS+ P + + FF FLH WLNAFAEML+FGDR+FY++WWNST+FSNYYRTWNVVVHDWLY+YVY+D L L R AM VFL SAV HEY+ + FFYPV LF++F G+ M + WNI W +F G GI + LY EWYARR+CP+ +TF ++ PRSW C Sbjct: 9 RRREGLGEEQEKGARGGEGNARTHGTPDLVQWTRHMEAVKTQFLEQAQRELAELLDRALWEAMQAYPKQDRPLPSAAPDSTSK------TQELHPGKRKVFITRKSLIDELMEVQHFRTIYHMFIAGLCVLIISTLAIDFIDEGRLMLEFDL--LLFSFGQLPLALMTWVPMFLSTLLV-PYQTLWLWARPRAGGAWMLGASLGCVLLAAHAVVLCVLPVHVSVRHELPPASRCVLVFEQVRLLMKSYSFLRETVPGIFCVRGGKGISPPSFSSYLYFLFCPTLIYRETYPRTPSIRWNYVAKNFAQVLGCLLYACFILGRLCVPVFANMSREPFSTRALLLSILHATGPGIFMLLLIFFAFLHCWLNAFAEMLRFGDRMFYRDWWNSTSFSNYYRTWNVVVHDWLYSYVYQDGLWLLGRRARGVAMLGVFLVSAVVHEYIFCFVLGFFYPVMLMLFLVFGGLLNFTMNDRHTGPAWNILMWTFLFMGQGIQVSLYCQEWYARRHCPLPQTTFWGMVTPRSWSCHP 525
BLAST of O-acyltransferase vs. Ensembl Mouse
Match: Soat2 (sterol O-acyltransferase 2 [Source:MGI Symbol;Acc:MGI:1332226]) HSP 1 Score: 120.553 bits (301), Expect = 4.688e-30 Identity = 75/278 (26.98%), Postives = 139/278 (50.00%), Query Frame = 1 Query: 178 INWKEKTEKKQKEFIDNVEKDMKLMFGKLKEVIIEEYDE----MTNETLDSPKKLCNINLKHDMLPEKQFQNRESVLTNLLNISHIRTVYHMFVAILIIFSLNTMLTDLIEKGGIIHTYHLEWVFWAFGGIGDVILLWLSMKSFTIFVYPCFLSWLYVRRMKILPISCVNKIYLVVYILTQISFVVIPLYFMCLIDLPPCSSAIVVLENIRLAMKIHAFIRENVAK--ELKSNELIETINFSRYLYFLFAPTLIYRDSYPKN------PTIRWSYVVS 975 + W E + +F++ ++++ + + ++ Y + + + DS K ++ K F R+S++ L+ + H RT+YHMF+A L + ++T+ D I++G ++ + L + ++FG + ++ W+ M T+ V P WL+ R + V+ + V+P++ +LPP S ++V E +RL MK ++F+RE V ++ E I +FS YLYFLF PTLIYR++YP++ P W+ VS Sbjct: 9 VQWTRHMEAVKTQFLEQAQRELAELLDRALWEAMQAYPKQDRPLPSAAPDSTSKTQELHPGK----RKVFITRKSLIDELMEVQHFRTIYHMFIAGLCVLIISTLAIDFIDEGRLMLEFDL--LLFSFGQLPLALMTWVPMFLSTLLV-PYQTLWLWARPRAGGAWMLGASLGCVLLAAHAVVLCVLPVHVSVRHELPPASRCVLVFEQVRLLMKSYSFLRETVPGIFCVRGGEGISPPSFSSYLYFLFCPTLIYRETYPRSWAVCSMPASSWAASVS 279
BLAST of O-acyltransferase vs. Ensembl Mouse
Match: Dgat1 (diacylglycerol O-acyltransferase 1 [Source:MGI Symbol;Acc:MGI:1333825]) HSP 1 Score: 117.087 bits (292), Expect = 2.134e-27 Identity = 71/236 (30.08%), Postives = 122/236 (51.69%), Query Frame = 1 Query: 868 ETINFSRYLYFLFAPTLIYRDSYPKNPTIRWSYVVSNFAQVIFCIVYMYYIFARFCVVYFQNFNSIHVTMQ--QLVLSVFGCMLPATLVFFICFFCFLHSWLNAFAEMLQFGDRLFYKEWWNSTTFSNYYRTWNVVVHDWLYTYVYRDILLLCRFNNRAAAMTIVFLFSAVFHEYVLIVMFRFFYPVLFVLFSGVGFGMMFIKGR---ARIWNIGFWVAMFTGNGIIMCLYSMEWY 1560 + + + YF+FAPTL Y ++P++P IR +++ +++F + ++ V QN M +++ + +P L++ I F+ F HS LNA AE+LQFGDR FY++WWN+ + + +++ WN+ VH W + Y+ +L +++ A T VFL SA FHEY++ V R F F + +I GR N WV + G + + +Y ++Y Sbjct: 256 DNLTYRDLYYFIFAPTLCYELNFPRSPRIRKRFLLRRVLEMLFFTQLQVGLIQQWMVPTIQNSMKPFKDMDYSRIIERLLKLAVPNHLIWLIFFYWFFHSCLNAVAELLQFGDREFYRDWWNAESVTYFWQNWNIPVHKWCIRHFYKP--MLRHGSSKWVARTGVFLTSAFFHEYLVSVPLRMFRLWAFTAMMA-QVPLAWIVGRFFQGNYGNAAVWVTLIIGQPVAVLMYVHDYY 488
BLAST of O-acyltransferase vs. UniProt/SwissProt
Match: sp|Q60457|SOAT1_CRIGR (Sterol O-acyltransferase 1 OS=Cricetulus griseus OX=10029 GN=SOAT1 PE=2 SV=1) HSP 1 Score: 405.601 bits (1041), Expect = 4.286e-134 Identity = 232/543 (42.73%), Postives = 323/543 (59.48%), Query Frame = 1 Query: 85 EIRNRRINETGIVKDYENQFSDDNATKFFQKINWKEKTEKKQKEFIDNVE------KDMKLMFGKLKEVIIEEYDEMTN-----ETLDSPKKLCNINLKHDML--PEKQ--FQNRESVLTNLLNISHIRTVYHMFVAILIIFSLNTMLTDLIEKGGIIHTYHLEWVFWAFGGIGDVILLWLSMKSFTIFV-YPCFLSWL--YVRRMKILPISCVNKIYLVVYILTQISFVVIPLYFMCLIDLPPCSSAIVVLENIRLAMKIHAFIRENV------AKELKSNELIETINFSRYLYFLFAPTLIYRDSYPKNPTIRWSYVVSNFAQVIFCIVYMYYIFARFCVVYFQNFNSIHVTMQQLVLSVFGCMLPATLVFFICFFCFLHSWLNAFAEMLQFGDRLFYKEWWNSTTFSNYYRTWNVVVHDWLYTYVYRDILLLCRFNNRAAAMTIVFLFSAVFHEYVLIVMFRFFYPVLFVLFSGVGFGMMFIKGRAR---IWNIGFWVAMFTGNGIIMCLYSMEWYARRNCPIYFSTFVDLLVPRSWFCQ 1632 +RNR ++++G + + + T+ +I K+ KK++ + E K++ F +IE+ + N T +++ N + D+ PEK F +R S+L L + HIRT+YHMF+ +LI+F L+T++ D I++G ++ ++L + +AFG + VI W +M T+ + Y F W Y + L S + + +V+ L + FV P Y + LPP S IV+LE IR+ MK H+F+RENV AKE S + T+N +YLYFLFAPTLIYRDSYP+ PT+RW YV F QV C+ Y+YYIF R C F+N + + LVL VF +LP L+ F+ FF FLH WLNAFAEML+FGDR+FYK+WWNST++SNYYRTWNVVVHDWLY Y Y+D+L ++AAM VF SAV HEY L V +FYPVLFVLF G FI +R IWNI W ++F G+G+I+C YS EWYAR++CP+ TF+D + PRSW CQ Sbjct: 8 SLRNR-LSKSGENPEQDEAQRSVSDTQSNGRITMKQLIAKKRQLAAEAEELKPLFLKEVGCHFDDFVTNLIEKSASLDNGGCALTTFSILEEMKNNHRAKDLRAPPEKGKIFISRRSLLDELFEVDHIRTIYHMFIGLLILFILSTLVVDYIDEGRLVLEFNL--LGYAFGKLPTVIWTWWAMFLSTLSIPYFLFQRWAHGYSKTSHPLIYSLSHGFFFLVFQLGILGFV--PTYVVLAYTLPPASRFIVILEQIRMVMKAHSFVRENVPRVLNAAKEKSSTVPVPTVN--QYLYFLFAPTLIYRDSYPRTPTVRWGYVAVQFLQVFGCLFYVYYIFERLCAPLFRNIKQEPFSARVLVLCVFNSILPGVLMLFLTFFAFLHCWLNAFAEMLRFGDRMFYKDWWNSTSYSNYYRTWNVVVHDWLYYYAYKDLLWFFSKRFKSAAMLAVFALSAVVHEYALAVCLSYFYPVLFVLFMFFGMAFNFIVNDSRKRPIWNIMVWASLFLGHGVILCFYSQEWYARQHCPLKNPTFLDYVRPRSWTCQ 543
BLAST of O-acyltransferase vs. UniProt/SwissProt
Match: sp|Q61263|SOAT1_MOUSE (Sterol O-acyltransferase 1 OS=Mus musculus OX=10090 GN=Soat1 PE=1 SV=2) HSP 1 Score: 402.134 bits (1032), Expect = 8.316e-133 Identity = 235/552 (42.57%), Postives = 323/552 (58.51%), Query Frame = 1 Query: 85 EIRNRRINETGIVKDYENQFSDDNATKFFQKINWKEKTEKK---QKEFIDNVEKDMKLMFGKLKEV----------IIEEYDEMTN--------ETLDSPKKLCNINLKHDMLPEKQ---FQNRESVLTNLLNISHIRTVYHMFVAILIIFSLNTMLTDLIEKGGIIHTYHLEWVFWAFGGIGDVILLWLSMKSFTIFV-YPCFLSWL--YVRRMKILPISCVNKIYLVVYILTQISFVVIPLYFMCLIDLPPCSSAIVVLENIRLAMKIHAFIRENV------AKELKSNELIETINFSRYLYFLFAPTLIYRDSYPKNPTIRWSYVVSNFAQVIFCIVYMYYIFARFCVVYFQNFNSIHVTMQQLVLSVFGCMLPATLVFFICFFCFLHSWLNAFAEMLQFGDRLFYKEWWNSTTFSNYYRTWNVVVHDWLYTYVYRDILLLCRFNNRAAAMTIVFLFSAVFHEYVLIVMFRFFYPVLFVLFSGVGFGMMFIKGRAR---IWNIGFWVAMFTGNGIIMCLYSMEWYARRNCPIYFSTFVDLLVPRSWFCQ 1632 +RNR + K EN D+ F T K+ +K + +++K +F +KEV +IE+ + N L+ KK N K P +Q F +R+S+L L + HIRT+YHMF+A+LI+F L+T++ D I++G ++ ++L + +AFG VI W +M T+ + Y F W Y + L S V+ + +V+ L + FV P Y + LPP S I++LE IRL MK H+F+REN+ AKE S + + T+N +YLYFLFAPTLIYRD+YP+ PT+RW YV F QV C+ Y+YYIF R C F+N + + LVL VF +LP L+ F+ FF FLH WLNAFAEML+FGDR+FYK+WWNST++SNYYRTWNVVVHDWLY YVY+D+L ++AAM VF SAV HEY L + +FYPVLFVLF G FI +R IWNI W ++F G G+I+C YS EWYAR++CP+ TF+D + PR+W C+ Sbjct: 2 SLRNR------LSKSGENPEQDEAQKNFMDTYRNGHITMKQLIAKKRLLAAEAEELKPLF--MKEVGCHFDDFVTNLIEKSASLDNGGCALTTFSILEEMKK--NHRAKDLRAPPEQGKIFISRQSLLDELFEVDHIRTIYHMFIALLILFVLSTIVVDYIDEGRLVLEFNL--LAYAFGKFPTVIWTWWAMFLSTLSIPYFLFQRWAHGYSKSSHPLIYSLVHGLLFLVFQLGVLGFV--PTYVVLAYTLPPASRFILILEQIRLIMKAHSFVRENIPRVLNAAKEKSSKDPLPTVN--QYLYFLFAPTLIYRDNYPRTPTVRWGYVAMQFLQVFGCLFYVYYIFERLCAPLFRNIKQEPFSARVLVLCVFNSILPGVLILFLSFFAFLHCWLNAFAEMLRFGDRMFYKDWWNSTSYSNYYRTWNVVVHDWLYYYVYKDLLWFFSKRFKSAAMLAVFALSAVVHEYALAICLSYFYPVLFVLFMFFGMAFNFIVNDSRKRPIWNIMVWASLFLGYGLILCFYSQEWYARQHCPLKNPTFLDYVRPRTWTCR 537
BLAST of O-acyltransferase vs. UniProt/SwissProt
Match: sp|O70536|SOAT1_RAT (Sterol O-acyltransferase 1 OS=Rattus norvegicus OX=10116 GN=Soat1 PE=2 SV=1) HSP 1 Score: 396.356 bits (1017), Expect = 1.517e-130 Identity = 236/558 (42.29%), Postives = 324/558 (58.06%), Query Frame = 1 Query: 67 MTSLDGEIRNRRINETGIVKDYENQFSDDNATKFFQ-----KINWKEKTEKKQKEFIDNVEKDMKLMFGKLKEVIIEEYDEMTN-----ETLDSP----------KKLCNINLKHDM-LPEKQ---FQNRESVLTNLLNISHIRTVYHMFVAILIIFSLNTMLTDLIEKGGIIHTYHLEWVFWAFGGIGDVILLWLSMKSFTIFV-YPCFLSWL--YVRRMKILPISCVNKIYLVVYILTQISFVVIPLYFMCLIDLPPCSSAIVVLENIRLAMKIHAFIRENV------AKELKSNELIETINFSRYLYFLFAPTLIYRDSYPKNPTIRWSYVVSNFAQVIFCIVYMYYIFARFCVVYFQNFNSIHVTMQQLVLSVFGCMLPATLVFFICFFCFLHSWLNAFAEMLQFGDRLFYKEWWNSTTFSNYYRTWNVVVHDWLYTYVYRDILLLCRFNNRAAAMTIVFLFSAVFHEYVLIVMFRFFYPVLFVLFSGVGFGMMFIKGRAR---IWNIGFWVAMFTGNGIIMCLYSMEWYARRNCPIYFSTFVDLLVPRSWFCQ 1632 M + +RNR + + EN D+ I K+ KK++ + +++K +F LKEV D +TN +LD+ +++ N + D+ P +Q F +R S+L L + HIRT+YHMF+A+LIIF L+T++ D I++G ++ + L + +AFG VI W +M T+ + Y F W Y + L S ++ + +V+ L + F IP Y + LPP S I++LE IRL MK H+++RENV AKE S + T+N +YLYFLFAPTLIYRDSYP+ PT+RW YV F QV C+ Y+YYIF R C F+N + + LVL VF +LP L+ F+ FF FLH WLNAFAEML+FGDR+FYK+WWNST++SNYYRTWNVVVHDWLY YVY+D+L R AAM VF SAV HEY L V +FYPVLFVLF G FI +R +WNI ++F G+G+I+C YS EWYAR+ CP+ TF+D + PR+W C+ Sbjct: 1 MVGEETSLRNR------LSRSAENPEQDEAQKNLLDTHRNGHITMKQLIAKKRQ--LAAEAEELKPLF--LKEVGCHFDDFVTNLIDKSASLDNGGCALTTFSILEEMKNNHRAKDLRAPPEQGKIFISRRSLLDELFEVDHIRTIYHMFIALLIIFILSTLVVDYIDEGRLVLEFSL--LAYAFGQFPIVIWTWWAMFLSTLAIPYFLFQRWAHGYSKSSHPLIYSLIHGAFFLVFQLGILGF--IPTYVVLAYTLPPASRFILILEQIRLVMKAHSYVRENVPRVLSAAKEKSSTVPVPTVN--QYLYFLFAPTLIYRDSYPRTPTVRWGYVAMQFLQVFGCLFYVYYIFERLCAPLFRNIKQEPFSARVLVLCVFNSILPGVLMLFLSFFAFLHCWLNAFAEMLRFGDRMFYKDWWNSTSYSNYYRTWNVVVHDWLYYYVYKDLLWFFSKRFRPAAMLAVFALSAVVHEYALAVCLSYFYPVLFVLFMFFGMAFNFIVNDSRKRPVWNIMVRASLFLGHGVILCFYSQEWYARQRCPLKNPTFLDYVRPRTWTCR 542
BLAST of O-acyltransferase vs. UniProt/SwissProt
Match: sp|P35610|SOAT1_HUMAN (Sterol O-acyltransferase 1 OS=Homo sapiens OX=9606 GN=SOAT1 PE=1 SV=3) HSP 1 Score: 395.586 bits (1015), Expect = 2.940e-130 Identity = 234/550 (42.55%), Postives = 310/550 (56.36%), Query Frame = 1 Query: 73 SLDGEIRNRRINETGIVKDYENQFSDDNATKFFQKINWKEKTEKKQKEFIDNVE------KDMKLMFGKLKEVIIEEYDEMTN--------ETLDSPKKLCNINLKHDMLPEKQ---FQNRESVLTNLLNISHIRTVYHMFVAILIIFSLNTMLTDLIEKGGIIHTYHLEWVFWAFGGIGDVILLWLSMKSFTIFVYPCFL--SWL--YVRRMKILPISCVNKIYLVVYILTQISFVVIPLYFMCLIDLPPCSSAIVVLENIRLAMKIHAFIRENV------AKELKSNELIETINFSRYLYFLFAPTLIYRDSYPKNPTIRWSYVVSNFAQVIFCIVYMYYIFARFCVVYFQNFNSIHVTMQQLVLSVFGCMLPATLVFFICFFCFLHSWLNAFAEMLQFGDRLFYKEWWNSTTFSNYYRTWNVVVHDWLYTYVYRDILLLCRFNNRAAAMTIVFLFSAVFHEYVLIVMFRFFYPVLFVLFSGVGFGMMFIKGRAR---IWNIGFWVAMFTGNGIIMCLYSMEWYARRNCPIYFSTFVDLLVPRSWFCQ 1632 SL + R N +D N + T +I+ K+ KK K + E K++ F +IE+ + N L+ K N K P +Q F R S+L LL + HIRT+YHMF+A+LI+F L+T++ D I++G ++ + L + +AFG V+ W M + F P FL W Y + L S + +++ + + F P Y + LPP S I++ E IR MK H+F+RENV AKE S I T+N +YLYFLFAPTLIYRDSYP+NPT+RW YV FAQV C Y+YYIF R C F+N + + LVL VF +LP L+ F+ FF FLH WLNAFAEML+FGDR+FYK+WWNST++SNYYRTWNVVVHDWLY Y Y+D L ++AAM VF SAV HEY L V FFYPVLFVLF G FI +R IWN+ W ++F GNG+++C YS EWYAR++CP+ TF+D + PRSW C+ Sbjct: 8 SLRNRLSKSRENPEED-EDQRNPAKESLETPSNGRIDIKQLIAKKIKLTAEAEELKPFFMKEVGSHFDDFVTNLIEKSASLDNGGCALTTFSVLEGEKN--NHRAKDLRAPPEQGKIFIARRSLLDELLEVDHIRTIYHMFIALLILFILSTLVVDYIDEGRLVLEFSL--LSYAFGKFPTVVWTWWIM-FLSTFSVPYFLFQHWATGYSKSSHPLIRSLFHGFLFMIFQIGVLGFG--PTYVVLAYTLPPASRFIIIFEQIRFVMKAHSFVRENVPRVLNSAKEKSSTVPIPTVN--QYLYFLFAPTLIYRDSYPRNPTVRWGYVAMKFAQVFGCFFYVYYIFERLCAPLFRNIKQEPFSARVLVLCVFNSILPGVLILFLTFFAFLHCWLNAFAEMLRFGDRMFYKDWWNSTSYSNYYRTWNVVVHDWLYYYAYKDFLWFFSKRFKSAAMLAVFAVSAVVHEYALAVCLSFFYPVLFVLFMFFGMAFNFIVNDSRKKPIWNVLMWTSLFLGNGVLLCFYSQEWYARQHCPLKNPTFLDYVRPRSWTCR 547
BLAST of O-acyltransferase vs. UniProt/SwissProt
Match: sp|O77760|SOAT1_CHLAE (Sterol O-acyltransferase 1 OS=Chlorocebus aethiops OX=9534 GN=SOAT1 PE=2 SV=1) HSP 1 Score: 395.586 bits (1015), Expect = 3.037e-130 Identity = 236/555 (42.52%), Postives = 313/555 (56.40%), Query Frame = 1 Query: 85 EIRNRRINETGIVKDYENQFSDDNATKFFQ---------KINWKEKTEKKQKEFIDNVE------KDMKLMFGKLKEVIIEEYDEMTN--------ETLDSPKKLCNINLKHDMLPEKQ---FQNRESVLTNLLNISHIRTVYHMFVAILIIFSLNTMLTDLIEKGGIIHTYHLEWVFWAFGGIGDVILLWLSMKSFTIFVYPCFL--SWL--YVRRMKILPISCVNKIYLVVYILTQISFVVIPLYFMCLIDLPPCSSAIVVLENIRLAMKIHAFIRENV------AKELKSNELIETINFSRYLYFLFAPTLIYRDSYPKNPTIRWSYVVSNFAQVIFCIVYMYYIFARFCVVYFQNFNSIHVTMQQLVLSVFGCMLPATLVFFICFFCFLHSWLNAFAEMLQFGDRLFYKEWWNSTTFSNYYRTWNVVVHDWLYTYVYRDILLLCRFNNRAAAMTIVFLFSAVFHEYVLIVMFRFFYPVLFVLFSGVGFGMMFIKGRAR---IWNIGFWVAMFTGNGIIMCLYSMEWYARRNCPIYFSTFVDLLVPRSWFCQ 1632 +RNR + K EN D++ K + +I+ K+ KK K + E K++ F +IE+ + N L+ K N K P +Q F R S+L LL + HIRT+YHMF+A+LI+F L+T++ D I++G ++ + L + +AFG V+ W M + F P FL W Y + L S + +V+ + + F P Y + LPP S I++ E IR MK H+F+RENV AKE S I T+N +YLYFLFAPTLIYRDSYP+NPT+RW YV FAQV C Y+YYIF R C F+N + + LVL VF +LP L+ F+ FF FLH WLNAFAEML+FGDR+FYK+WWNST++SNYYRTWNVVVHDWLY Y Y+D L ++AAM VF SAV HEY L V FFYPVLFVLF G FI +R IWN+ W ++F GNG+++C YS EWYAR++CP+ TF+D + PRSW C+ Sbjct: 8 SLRNR------LSKSRENPEEDEDQRKPAKESLEAPSNGRIDIKQLIAKKIKLTAEAEELKPFFMKEVGSHFDDFVTNLIEKSASLDNGGCALTTFSILEGEKN--NHRAKDLRAPPEQGKIFIARRSLLDELLEVDHIRTIYHMFIALLILFILSTLVVDYIDEGRLVLEFSL--LSYAFGKFPTVVWTWWIM-FLSTFSVPYFLFQRWATGYSKSSHPLINSLFHGFLFMVFQIGILGFG--PTYVVLAYTLPPASRFIIIFEQIRFVMKAHSFVRENVPRVLNSAKEKSSTVPIPTVN--QYLYFLFAPTLIYRDSYPRNPTVRWGYVAMQFAQVFGCFFYVYYIFERLCAPLFRNIKQEPFSARVLVLCVFNSILPGVLILFLTFFAFLHCWLNAFAEMLRFGDRMFYKDWWNSTSYSNYYRTWNVVVHDWLYYYAYKDFLWFFSKRFKSAAMLAVFAVSAVVHEYALAVCLSFFYPVLFVLFMFFGMAFNFIVNDSRKKPIWNVMMWTSLFLGNGVLLCFYSQEWYARQHCPLKNPTFLDYVRPRSWTCR 547
BLAST of O-acyltransferase vs. TrEMBL
Match: A0A2T7PBB2 (O-acyltransferase OS=Pomacea canaliculata OX=400727 GN=C0Q70_09982 PE=3 SV=1) HSP 1 Score: 509.99 bits (1312), Expect = 9.825e-173 Identity = 264/531 (49.72%), Postives = 350/531 (65.91%), Query Frame = 1 Query: 79 DGEIRNRRINETGIVKDYENQFSDDNATKFFQKINWKEKTEKKQKEFIDNVEKDMKLMFGKLKEVIIEEYDEMTNETLDSPKKLCNINLK-----HDMLPEKQFQNRESVLTNLLNISHIRTVYHMFVAILIIFSLNTMLTDLIEKGGIIHTYHLEWVFWAFGGIGDVILLWLSMK-SFTIFVYPCFLSWLYVRRMKILPISCVNKIYLVVYILTQISFVVIPLYFMCLIDLPPCSSAIVVLENIRLAMKIHAFIRENVA-----KELKSNELIETINFSRYLYFLFAPTLIYRDSYPKNPTIRWSYVVSNFAQVIFCIVYMYYIFARFCVVYFQNFNSIHVTMQQLVLSVFGCMLPATLVFFICFFCFLHSWLNAFAEMLQFGDRLFYKEWWNSTTFSNYYRTWNVVVHDWLYTYVYRDILLLCRFNNRAAAMTIVFLFSAVFHEYVLIVMFRFFYPVLFVLFSGVGFGMMFI--KGRARIWNIGFWVAMFTGNGIIMCLYSMEWYARRNCPIYFSTFVDLLVPRSWFCQ 1632 +G++ N+ + G+ + Q + N ++ K ++ D++ + + +L + I E +++ +L L + K + LP+K F R SVLT LL +HI+T+YH+FVAILI+FSLNT++ D +EKG + + L + WAFG + V+ W+ M+ S + VYP F W RR P + ++L V I QI+F+ IP+ + ++PP SS IV E +R MK HAFIRENV+ K+ ++E +FS+YLYFLFAPTLIYRD+YP+ TI+W YVVSNFAQV+ C+ Y YYIF RFCV FQNFN VT + L+LSVFG M+PATLV FI FF LHSWLNAFAEML+FGDRLFYK+WWNSTTFSNYYRTWNVVVHDWLYTYVY+D+ L NRA M +VFL SA+FHEY+L+V FRFFYPVLF +F+G GFG +F+ K +R WN+ WV +FTGNG++MCLYSMEWYARR+CP+ +F D L+PRSW C Sbjct: 12 NGDLHNK-VENVGMKSTKDEQVHEINL----------QRIRDKAQQLRDDLLRQLNAQLDELFDNFISEVEQIEQASLLGNGDLKTLKCKSKKRKNGELPDKIFVQRRSVLTELLETTHIQTIYHIFVAILIVFSLNTLVYDWVEKGTLNLNFDL--IVWAFGKLPKVMSSWVCMQLSTLLIVYPAFYYWSTHRRPG--PTGVYDIVWLFVAIAYQIAFLTIPILHLVENNMPPASSVIVTCEQVRFIMKTHAFIRENVSRVIYCKKDDNDEENGCPDFSKYLYFLFAPTLIYRDNYPRTKTIKWQYVVSNFAQVLACLFYTYYIFERFCVPVFQNFNRESVTPRALLLSVFGSMMPATLVLFIGFFAILHSWLNAFAEMLRFGDRLFYKDWWNSTTFSNYYRTWNVVVHDWLYTYVYKDVYKLMGSKNRAGPMAMVFLISAMFHEYILMVTFRFFYPVLFFMFAGAGFGFIFLTEKVSSRSWNVFMWVMLFTGNGMLMCLYSMEWYARRSCPVITDSFFDYLIPRSWMCD 527
BLAST of O-acyltransferase vs. TrEMBL
Match: A0A2C9JQ14 (O-acyltransferase OS=Biomphalaria glabrata OX=6526 GN=106063279 PE=3 SV=1) HSP 1 Score: 506.908 bits (1304), Expect = 1.494e-171 Identity = 264/527 (50.09%), Postives = 348/527 (66.03%), Query Frame = 1 Query: 97 RRINETGIVKDYENQFSDDNATKFFQKINWKEKTEKKQKEFIDNVEK-----DMKLMFGKLKEVIIEEYDEMTNETLDSPKKLCNINLKHDMLPEKQFQNRESVLTNLLNISHIRTVYHMFVAILIIFSLNTMLTDLIEKGGIIHTYHLEW--VFWAFGGIGDVILLWLSMKSFTIF-VYPCFLSWLYVRRMKILPISCVNKIYLVVYILTQISFVVIPLYFMCLIDLPPCSSAIVVLENIRLAMKIHAFIRENVAKEL---KSNELIETI---NFSRYLYFLFAPTLIYRDSYPKNPTIRWSYVVSNFAQVIFCIVYMYYIFARFCVVYFQNFNSIHVTMQQLVLSVFGCMLPATLVFFICFFCFLHSWLNAFAEMLQFGDRLFYKEWWNSTTFSNYYRTWNVVVHDWLYTYVYRDILLLCRFNNRAAAMTIVFLFSAVFHEYVLIVMFRFFYPVLFVLFSGVGFGMMFI--KGRARIWNIGFWVAMFTGNGIIMCLYSMEWYARRNCPIYFSTFVDLLVPRSWFC 1629 +RIN I +D+ Q D ++ E+ F+ VE+ D+ + G +K T E K+ K LP+K F R SVLT L ISH+RT+YH+FVA+LI+FSLNTML D++EK HT +L + + WAFG V+ LW+ M+ T+ VYP F W R K I ++ I++ + I+ Q++F++IPL+++ DLPP SS +V E R MK H+FIREN A+ + K ++ ET +FS+YLYFLF PTL+YRD+YP+ TI W YVV+NF QV+ C++Y+YYIF RFCV FQNFN H+T + +LS+FGCM+P TL+ FI FF LHSW+NAFAEML+FGDRLFYK+WWNSTTFSNYYRTWNVVVHDWLYTY+Y+DI L NR AM VFL SAVFHEY+L F+FFYPVLFV+F+G GFG +F+ KG +R WN+ WVA+F GNG++MCLYSME+YAR+NC + +DL++PRSWFC Sbjct: 13 KRINHQRI-RDHAQQLKLDLLDSMSNQL------EELLDGFVSTVEQIEVGDDLNVQNGSIKNHCPSCASHPTEEVASKKKE------KTGELPDKVFVTRSSVLTELFEISHVRTIYHIFVAVLIVFSLNTMLYDVLEK----HTLNLNFGMIQWAFGKFPKVMALWMMMQGSTLLIVYPAFYCWASYRTPKNSGI--LDVIWISLVIIYQLAFLLIPLFYLIEHDLPPASSVVVTAEQTRFLMKTHSFIRENTARVMYKKKDDDDQETSLCPDFSKYLYFLFCPTLVYRDNYPRTQTISWKYVVTNFLQVLACLIYIYYIFERFCVPVFQNFNKDHITAKGFILSMFGCMMPGTLLLFISFFAILHSWMNAFAEMLRFGDRLFYKDWWNSTTFSNYYRTWNVVVHDWLYTYIYKDICKLVGPRNRPGAMACVFLISAVFHEYILTCTFKFFYPVLFVMFAGAGFGFIFLTDKGSSRSWNVFMWVALFIGNGLLMCLYSMEFYARQNCQASTESLLDLMIPRSWFC 520
BLAST of O-acyltransferase vs. TrEMBL
Match: A0A2C9JQ08 (O-acyltransferase OS=Biomphalaria glabrata OX=6526 GN=106063279 PE=3 SV=1) HSP 1 Score: 504.212 bits (1297), Expect = 9.803e-171 Identity = 255/506 (50.40%), Postives = 343/506 (67.79%), Query Frame = 1 Query: 151 DNATKFFQKINWKEKTEKKQKEFIDNVEKDMKLMFGKLKEVI--IEEYDEMTNETLDSPKKLCNINLKHDMLPEKQFQNRESVLTNLLNISHIRTVYHMFVAILIIFSLNTMLTDLIEKGGIIHTYHLEW--VFWAFGGIGDVILLWLSMKSFTIF-VYPCFLSWLYVRRMKILPISCVNKIYLVVYILTQISFVVIPLYFMCLIDLPPCSSAIVVLENIRLAMKIHAFIRENVAKEL---KSNELIETI---NFSRYLYFLFAPTLIYRDSYPKNPTIRWSYVVSNFAQVIFCIVYMYYIFARFCVVYFQNFNSIHVTMQQLVLSVFGCMLPATLVFFICFFCFLHSWLNAFAEMLQFGDRLFYKEWWNSTTFSNYYRTWNVVVHDWLYTYVYRDILLLCRFNNRAAAMTIVFLFSAVFHEYVLIVMFRFFYPVLFVLFSGVGFGMMFI--KGRARIWNIGFWVAMFTGNGIIMCLYSMEWYARRNCPIYFSTFVDLLVPRSWFC 1629 D K ++ ++ + + +D++ ++ + + IE D++ + KK K LP+K F R SVLT L ISH+RT+YH+FVA+LI+FSLNTML D++EK HT +L + + WAFG V+ LW+ M+ T+ VYP F W R K I ++ I++ + I+ Q++F++IPL+++ DLPP SS +V E R MK H+FIREN A+ + K ++ ET +FS+YLYFLF PTL+YRD+YP+ TI W YVV+NF QV+ C++Y+YYIF RFCV FQNFN H+T + +LS+FGCM+P TL+ FI FF LHSW+NAFAEML+FGDRLFYK+WWNSTTFSNYYRTWNVVVHDWLYTY+Y+DI L NR AM VFL SAVFHEY+L F+FFYPVLFV+F+G GFG +F+ KG +R WN+ WVA+F GNG++MCLYSME+YAR+NC + +DL++PRSWFC Sbjct: 9 DQTLKRINHQRIRDHAQQLKLDLLDSMSNQLEELLDGFVSTVEQIEVGDDLNVQNGSIKKKE-----KTGELPDKVFVTRSSVLTELFEISHVRTIYHIFVAVLIVFSLNTMLYDVLEK----HTLNLNFGMIQWAFGKFPKVMALWMMMQGSTLLIVYPAFYCWASYRTPKNSGI--LDVIWISLVIIYQLAFLLIPLFYLIEHDLPPASSVVVTAEQTRFLMKTHSFIRENTARVMYKKKDDDDQETSLCPDFSKYLYFLFCPTLVYRDNYPRTQTISWKYVVTNFLQVLACLIYIYYIFERFCVPVFQNFNKDHITAKGFILSMFGCMMPGTLLLFISFFAILHSWMNAFAEMLRFGDRLFYKDWWNSTTFSNYYRTWNVVVHDWLYTYIYKDICKLVGPRNRPGAMACVFLISAVFHEYILTCTFKFFYPVLFVMFAGAGFGFIFLTDKGSSRSWNVFMWVALFIGNGLLMCLYSMEFYARQNCQASTESLLDLMIPRSWFC 503
BLAST of O-acyltransferase vs. TrEMBL
Match: A0A210R6J1 (O-acyltransferase OS=Mizuhopecten yessoensis OX=6573 GN=KP79_PYT00054 PE=3 SV=1) HSP 1 Score: 503.827 bits (1296), Expect = 2.445e-170 Identity = 253/494 (51.21%), Postives = 335/494 (67.81%), Query Frame = 1 Query: 187 KEKTEKKQKEFIDNVEKDMKLMFGK-LKEVIIEEYDEMTNETLDSPKKLCNINLKHDMLPEKQFQNRESVLTNLLNISHIRTVYHMFVAILIIFSLNTMLTDLIEKGGIIHTYHLEWVFWAFGGIGDVILLWLSMK-SFTIFVYPCFLSWLYVRRMKILPISCVNKIYLVVYILTQISFVVIPLYFMCLIDLPPCSSAIVVLENIRLAMKIHAFIRENVAKELKSNELIETI---------NFSRYLYFLFAPTLIYRDSYPKNPTIRWSYVVSNFAQVIFCIVYMYYIFARFCVVYFQNFNSIHVTMQQLVLSVFGCMLPATLVFFICFFCFLHSWLNAFAEMLQFGDRLFYKEWWNSTTFSNYYRTWNVVVHDWLYTYVYRDILLLCRFNNRAAAMTIVFLFSAVFHEYVLIVMFRFFYPVLFVLFSGVGFGMMFI--KGRARIWNIGFWVAMFTGNGIIMCLYSMEWYARRNCPIYFSTFVDLLVPRSWFC 1629 K +T+K +K+ + + +++ + + EV ++ N+ S LP+K F R S+LT L ISHIRT+YH+FVAILI+FSLNT + DL+ +G + + L + W G V+ LW+ M S + VYP F W+ R P++ + L +++L QI+F+V+P +++ +PP S+ I+ E +RL MK+HAF+REN+ K L SN+ + +FS+YLYFLFAPTL+YRDSYP+ TIRW+YVV+NFAQV+ C++Y YYIF RFCV F NFN HVT + L+LSVFGCMLP TLV FI FF LHSWLNAFAEML+FGDR+FYK+WWNSTTF+NYYRTWN+VVHDWLYTY+Y+D L NRA AM +VFL SAV HEY+L V F FFYPVLFV+F G GF +F+ KG +R WN+ WVA+F GNG++MCLYSMEWYAR NCP+ TF+D ++PRSW C Sbjct: 38 KNQTQKLKKDVVQQLSSELEQLLQDFVTEVEHLGHNGDANDNYTSFPSKAEKRRHTGELPDKVFHLRRSMLTELFEISHIRTIYHIFVAILIVFSLNTFVYDLVNEGRLNLDFGL--MKWTLGKFPKVMALWVCMTLSTLVIVYPTFYYWVANRTPG--PVNKTDMFALGLFVLYQIAFIVLPNHYIMEHQIPPASAVIITTEQVRLIMKVHAFVRENIPKVLASNKKDDGDVDKKTNLCPDFSKYLYFLFAPTLVYRDSYPRTKTIRWNYVVTNFAQVLACLLYTYYIFERFCVPVFNNFNKDHVTPKALLLSVFGCMLPGTLVLFIAFFAILHSWLNAFAEMLRFGDRMFYKDWWNSTTFANYYRTWNIVVHDWLYTYIYKDFHRLLGPRNRAGAMALVFLISAVVHEYILTVCFSFFYPVLFVMFMGAGFTFIFVTDKGVSRSWNVFLWVALFIGNGLLMCLYSMEWYARINCPVNTDTFLDYIIPRSWTC 527
BLAST of O-acyltransferase vs. TrEMBL
Match: A0A0L8GFZ3 (O-acyltransferase OS=Octopus bimaculoides OX=37653 GN=OCBIM_22034018mg PE=3 SV=1) HSP 1 Score: 500.745 bits (1288), Expect = 6.301e-170 Identity = 255/467 (54.60%), Postives = 329/467 (70.45%), Query Frame = 1 Query: 268 EVIIEEYDEMTNETLDSPKKLCNIN-----LKHDMLPEKQFQNRESVLTNLLNISHIRTVYHMFVAILIIFSLNTMLTDLIEKGGIIHTYHLEWVFWAFGGIGDVILLWLSMKSFTIFV-YPCFLSWLYVRRMKILPISCVNKIYLVVYILTQISFVVIPLYFMCLIDLPPCSSAIVVLENIRLAMKIHAFIRENVAKELKSNELIETIN----FSRYLYFLFAPTLIYRDSYPKNPTIRWSYVVSNFAQVIFCIVYMYYIFARFCVVYFQNFNSIHVTMQQLVLSVFGCMLPATLVFFICFFCFLHSWLNAFAEMLQFGDRLFYKEWWNSTTFSNYYRTWNVVVHDWLYTYVYRDILLLCRFNNRAAAMTIVFLFSAVFHEYVLIVMFRFFYPVLFVLFSGVGFGMMFI--KGRARIWNIGFWVAMFTGNGIIMCLYSMEWYARRNCPIYFSTFVDLLVPRSWFCQ 1632 E + EE+ + +P+ L I K LPEK F NR SVLT LL I+HI+T+Y++FVAIL++FSLNT++ DLI+ G + ++L + WAFG V+ LW+ M+ T+ + YP F W KI P + I+L +++ Q+ F V+P+ ++ +LPP S+ I+V E +RL MK+H+F+RENV K L + N FS+YLYFLF+PTLIYRDSYP+ IRW+YVVSNF+QV+ C+ Y YYIF RFCV F+NFN HVT + L+LSVFGCMLP TLV FI FF LHSWLNAFAEML+FGDRLFYK+WWNSTTFSNYYRTWNVVVHDWLYTY+Y+D+ + + R +T VFL SAVFHEYVL+V F FFYPVLFV+F+G GFG +F+ KG +R WN+ WVA+F GNG++MCLYS+EWYAR+NCP + F D L+PRSW C Sbjct: 6 ECLFEEFVSEVEQIEQNPQSLFEIKPNRVKRKDGELPEKVFVNRRSVLTELLEITHIQTIYNIFVAILLVFSLNTIVYDLIDTGRLHLDFNL--IQWAFGKFPKVMALWVCMQLATLLIFYPAFYYW--ASSKKIRPYKVWDWIWLGLFVAYQLLFFVLPVNYLYENNLPPASAVIIVTEQLRLIMKVHSFVRENVPKVLNYKKADSDDNVCPDFSKYLYFLFSPTLIYRDSYPRTQKIRWNYVVSNFSQVLACLFYTYYIFERFCVPVFRNFNREHVTPKALLLSVFGCMLPGTLVLFIGFFAILHSWLNAFAEMLRFGDRLFYKDWWNSTTFSNYYRTWNVVVHDWLYTYIYKDVYTILGYKMRNVGLTSVFLISAVFHEYVLVVSFGFFYPVLFVMFAGAGFGFVFLTDKGVSRSWNVFMWVALFIGNGLLMCLYSLEWYARQNCPATTNDFFDYLIPRSWTCD 468
BLAST of O-acyltransferase vs. Ensembl Cavefish
Match: soat2 (sterol O-acyltransferase 2-like [Source:NCBI gene;Acc:103034708]) HSP 1 Score: 361.688 bits (927), Expect = 4.294e-118 Identity = 203/542 (37.45%), Postives = 305/542 (56.27%), Query Frame = 1 Query: 61 LAMTSLDGEIRNRRINETGIV----KDYENQFSDDNATKFFQK--INWKEKTEKKQKEFIDNVEKDMKLMFGKLKEVIIEEYDEMTNETLD--SPKKLCNINLKHDMLPEKQFQNRESVLTNLLNISHIRTVYHMFVAILIIFSLNTMLTDLIEKGGIIHTYHLEWVFWAFGGIGDVILLWLSMKSFTIF-VYPCFLSW--LYVRRMKILPISCVNKIYLVVYILTQISFVVIPLYFMCLIDLPPCSSAIVVLENIRLAMKIHAFIRENVA----KELKSNELIETINFSRYLYFLFAPTLIYRDSYPKNPTIRWSYVVSNFAQVIFCIVYMYYIFARFCVVYFQNFNSIHVTMQQLVLSVFGCMLPATLVFFICFFCFLHSWLNAFAEMLQFGDRLFYKEWWNSTTFSNYYRTWNVVVHDWLYTYVYRDILLLCRFNNRAAAMTIVFLFSAVFHEYVLIVMFRFFYPVLFVLFSGVGFGMMFI---KGRARIWNIGFWVAMFTGNGIIMCLYSMEWYARRNCPIYFSTFVDLLVPRSWFCQ 1632 +A S ++ +R+ +T + K+ + + N T+ + + W E+ + E I+ ++ M + K + + T ++ + +H M K F R S+L L ISH+RT+YHMF+A L +F ++T+ D I++G ++ + L F+AFG +G V+ W M ++T+ Y W LY R + +S + L+V + + + P++ + LPP S IV+LE IR MK ++FIRE V ++ E S YLYFLF PTLIYR++YP+NP IRW+YV NFA+++ + Y+Y+I R C+ F N ++ + + LVL++F LP L+ + FF FLH WLNAFAEML+F DR+FYK+WWNST+F+NYYRTWN+VVHDWLY Y YRD + L R+ A VF SA HEY + F FFYPV+FVLF+ +G F K + +WN+ W +F G G+ +CLY +EWYA+ +CP + F +L+ PRSW C Sbjct: 1 MATNSSTSKVVHRKNGKTSVTSSSPKENGSTRQESNHTELHSRDTVQWARDVERIKMEVIEQMKVQMSEVLDKALTDSLRSLSQSTQWDINGNTHSHTDEKARRHRMEDGKVFVARRSILDELFEISHVRTIYHMFIAALFLFIISTLAVDYIDQGRLVLDFDL--FFYAFGLLGTVVWAWFIMFTYTLLGPYHVLSQWADLYHRSSWNMSVSVATAVILLVAQMGVLGY--FPVFVVVHYQLPPASRFIVILEQIRFLMKSYSFIRETVVAVVREKTAKGESCRFPTLSNYLYFLFCPTLIYREAYPRNPYIRWNYVWRNFAKILGSLFYLYFILVRLCIPVFMNESNRPFSTRTLVLAIFHSTLPGMLMLLLGFFAFLHCWLNAFAEMLRFADRMFYKDWWNSTSFANYYRTWNIVVHDWLYYYAYRDFVWLTGHRFRSVATMSVFAVSAFVHEYAFTMGFGFFYPVMFVLFAVIGGVFNFTLNDKRKGPMWNVIMWTCLFIGQGVQVCLYCLEWYAQVHCPRTGTGFWELVTPRSWTCN 538
BLAST of O-acyltransferase vs. Ensembl Cavefish
Match: soat2 (sterol O-acyltransferase 2-like [Source:NCBI gene;Acc:103034708]) HSP 1 Score: 353.984 bits (907), Expect = 2.350e-115 Identity = 199/534 (37.27%), Postives = 304/534 (56.93%), Query Frame = 1 Query: 61 LAMTSLDGEIRNRRINETGIVKDYENQFSDDNATKFFQKINWKEKTEKKQKEFIDNVEKDMKLMFGKLKEVIIEEYDEMTNETLDSPKKLCNINLKHDMLPEKQFQNRESVLTNLLNISHIRTVYHMFVAILIIFSLNTMLTDLIEKGGIIHTYHLEWVFWAFGGIGDVILLWLSMKSFTIF-VYPCFLSW--LYVRRMKILPISCVNKIYLVVYILTQISFVVIPLYFMCLIDLPPCSSAIVVLENIRLAMKIHAFIRENVA----KELKSNELIETINFSRYLYFLFAPTLIYRDSYPKNPTIRWSYVVSNFAQVIFCIVYMYYIFARFCVVYFQNFNSIHVTMQQLVLSVFGCMLPATLVFFICFFCFLHSWLNAFAEMLQFGDRLFYKEWWNSTTFSNYYRTWNVVVHDWLYTYVYRDILLLCRFNNRAAAMTIVFLFSAVFHEYVLIVMFRFFYPVLFVLFSGVGFGMMFI---KGRARIWNIGFWVAMFTGNGIIMCLYSMEWYARRNCPIYFSTFVDLLVPRSWFCQ 1632 +A S ++ +R+ +T + + + +T+ Q+ N E + ++ +VE+ + ++K + E D+ ++L S + + + D+ E + L ISH+RT+YHMF+A L +F ++T+ D I++G ++ + L F+AFG +G V+ W M ++T+ Y W LY R + +S + L+V + + + P++ + LPP S IV+LE IR MK ++FIRE V ++ E S YLYFLF PTLIYR++YP+NP IRW+YV NFA+++ + Y+Y+I R C+ F N ++ + + LVL++F LP L+ + FF FLH WLNAFAEML+F DR+FYK+WWNST+F+NYYRTWN+VVHDWLY Y YRD + L R+ A VF SA HEY + F FFYPV+FVLF+ +G F K + +WN+ W +F G G+ +CLY +EWYA+ +CP + F +L+ PRSW C Sbjct: 1 MATNSSTSKVVHRKNGKTSVTSSSPKE---NGSTR--QESNHTELHSRDTVQWARDVERIKMEVIEQMKVQMSEVLDKALTDSLRSLSQ----STQWDINGNTHSHTDEKARSELFEISHVRTIYHMFIAALFLFIISTLAVDYIDQGRLVLDFDL--FFYAFGLLGTVVWAWFIMFTYTLLGPYHVLSQWADLYHRSSWNMSVSVATAVILLVAQMGVLGY--FPVFVVVHYQLPPASRFIVILEQIRFLMKSYSFIRETVVAVVREKTAKGESCRFPTLSNYLYFLFCPTLIYREAYPRNPYIRWNYVWRNFAKILGSLFYLYFILVRLCIPVFMNESNRPFSTRTLVLAIFHSTLPGMLMLLLGFFAFLHCWLNAFAEMLRFADRMFYKDWWNSTSFANYYRTWNIVVHDWLYYYAYRDFVWLTGHRFRSVATMSVFAVSAFVHEYAFTMGFGFFYPVMFVLFAVIGGVFNFTLNDKRKGPMWNVIMWTCLFIGQGVQVCLYCLEWYAQVHCPRTGTGFWELVTPRSWTCN 521
BLAST of O-acyltransferase vs. Ensembl Cavefish
Match: ENSAMXT00000014398.2 (pep primary_assembly:Astyanax_mexicanus-2.0:APWO02000700.1:19594:35534:1 gene:ENSAMXG00000013993.2 transcript:ENSAMXT00000014398.2 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 322.783 bits (826), Expect = 1.272e-103 Identity = 173/378 (45.77%), Postives = 235/378 (62.17%), Query Frame = 1 Query: 340 NLKHDMLPE---KQFQNRESVLTNLLNISHIRTVYHMFVAILIIFSLNTMLTDLIEKGGIIHTYHLEWVFWAFGGIGDVILLWLSM-KSFTIFVYPCFLSWLYVRRMKILPISCVNKIYLVVYILTQISFVVIPLYFMCLIDLPPCSSAIVVLENIRLAMKIHAFIRENVAK----ELKSNELIETINFSRYLYFLFAPTLIYRDSYPKNPTIRWSYVVSNFAQVIFCIVYMYYIFARFCVVYFQNFNSIHVTMQQLVLSVFGCMLPATLVFFICFFCFLHSWLNAFAEMLQFGDRLFYKEWWNSTTFSNYYRTWNVVVHDWLYTYVYRDILLLCRFNNRAAAMTIVFLFSAVFHEYVLIVMFRFFYPVLFVLFSGVG 1449 L+H + + KQF R S+L L + HIRT+YHMF+A+LI+F L+T++ D I++G ++ + L + +AFG V++ W+ M S + Y SW ++ + + +P Y + LPP S I++LE +RL MK+H+FIREN+ + ++ + YLYFLFAPTLIYRD+YP+NP +RWSYV + QV+ C+ Y YY+F R C+ F++ ++ +VL VF +LP LV F+ FF FLH WLNAFAEML+FGDR+FYK+WWNST+F+NYYRTWNVVVHDWLY YVYRD L + + RAAAM IVF SAV HEYVL + F FFYPVLF LF G Sbjct: 108 KLRHTRVSQNQCKQFVIRRSLLDELFEVDHIRTIYHMFIALLILFILSTLVVDFIDEGRLVLDFDL--LVYAFGQFPLVVVTWICMFMSALVVPYVLLHSWAVAYPTSRHRSLLTLLAGGLLLLYQGLGLGFLPTYIVLRNGLPPASRFILILEQVRLMMKVHSFIRENIQRVWSSGRDGSDSSAVPQVTPYLYFLFAPTLIYRDNYPRNPYVRWSYVATKLLQVLGCLFYAYYVFVRLCIPQFRSLQLF--DLRAMVLCVFNSILPGVLVLFLGFFAFLHCWLNAFAEMLRFGDRMFYKDWWNSTSFANYYRTWNVVVHDWLYYYVYRDFLWMSQKRFRAAAMFIVFTVSAVVHEYVLAICFGFFYPVLFCLFMCFG 481
BLAST of O-acyltransferase vs. Ensembl Cavefish
Match: soat1 (sterol O-acyltransferase 1 [Source:ZFIN;Acc:ZDB-GENE-081105-177]) HSP 1 Score: 315.464 bits (807), Expect = 2.433e-101 Identity = 180/428 (42.06%), Postives = 251/428 (58.64%), Query Frame = 1 Query: 376 QNR-ESVLTNLLNISHIRTVYHMFVAILIIFSLNTMLTDLIEKGGIIHTYHLEWVFWAFGGIGDVILLWLSMKSFTIFVYPCFLSWLYVRRMKILPISCVNKIYLVVYILTQISFVVIPLYFMCLIDLPPCSSAIVVLENIRLAMKIHAFIRENVAK----ELKSNELIETINFSRYLYFLFAPTLIYRDSYPKNPTIRWSYVVSNFAQVIFCIVYMYYIFARFCVVYFQNFNSIHVTMQQLVLSVFGCMLPATLVFFICFFCFLHSWLNAFAEMLQFGDRLFYKEWWNSTTFSNYYRTWNVVVHDWLYTYVYRDILLLCRFNNRAAAMTIVFLFSAVFHEYVLIVMFRFFYPVLFVLFSGVGFGMMF-----IKGRARIWNIGFWVAMFTGNGIIMCLYSMEWYARRNCPIYFSTFVDLLVPRSWFC 1629 NR +L++L + HIRT+YHMF+A+LI+F L+T++ D I++G ++ + L + +AFG V++ W+ M F+S L V Y++++ + +P Y + LPP S I++LE +RL MK+H+FIREN+ + ++ + YLYFLF V+ C+ Y YY+F R C+ F++ ++ +VL VF +LP LV F+ FF FLH WLNAFAEML+FGDR+FYK+WWNST+F+NYYRTWNVVVHDWLY YVYRD L + + RAAAM IVF SAV HEYVL + F FFYPVLF LF + FGMMF + + +WN+ W A+F G G+++CLYS EWYA+ CP+ + +DLL PRSW C Sbjct: 70 SNRPRPLLSDLFEVDHIRTIYHMFIALLILFILSTLVVDFIDEGRLVLDFDL--LVYAFGQFPLVVVTWICM----------FMSALVVP-------------YVLLHSWAGLGLGFLPTYIVLRNGLPPASRFILILEQVRLMMKVHSFIRENIQRVWSSGRDGSDSSAVPQVTPYLYFLF---------------------------VLGCLFYAYYVFVRLCIPQFRSLQLF--DLRAMVLCVFNSILPGVLVLFLGFFAFLHCWLNAFAEMLRFGDRMFYKDWWNSTSFANYYRTWNVVVHDWLYYYVYRDFLWMSQKRFRAAAMFIVFTVSAVVHEYVLAICFGFFYPVLFCLF--MCFGMMFNFILHDRRKGPVWNVIMWTALFLGQGVLICLYSQEWYAQIYCPLQEPSLLDLLKPRSWTC 441
BLAST of O-acyltransferase vs. Ensembl Cavefish
Match: ENSAMXT00000047082.1 (pep primary_assembly:Astyanax_mexicanus-2.0:APWO02000700.1:23967:37034:1 gene:ENSAMXG00000013993.2 transcript:ENSAMXT00000047082.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 305.064 bits (780), Expect = 2.020e-97 Identity = 187/474 (39.45%), Postives = 266/474 (56.12%), Query Frame = 1 Query: 250 MFGKLKEVIIEEYDEMTNETLDSPKK-----LCNINLKH--DMLPEKQFQNRESVLTNLLNISHIRTVYHMFVAILIIFSLNTMLTDLIEKGGIIHTYHLEWVFWAFGGIGDVILLWLSM-KSFTIFVYPCFLSWLYVRRMKILPISCVNKIYLVVYILTQISFVVIPLYFMCLIDLPPCSSAIVVLENIRLAMKIHAFIRENVAKELKSNELIETINFSRYLYFLFAPTLIYRDSYPKNPTIRWSYVVSNFAQVIFCIVYMYYIFARFCVVYFQNFNSIHVTMQQLVLSVFGCMLPATLVFFICFFCFLHSWLNAFAEMLQFGDRLFYKEWWNSTTFSNYYRTWNVVVHDWLYTYVYRDILLLCRFNNRAAAMTIVFLFSAVFHEYVLIVMFRFFYPVLFVLFSGVGFGMMF-----IKGRARIWNIGFWVAMFTGNGIIMCLYSMEWYARRNCPIYFSTF-VDLLVPRSWFC 1629 ++ KLK +++++D +E +DS + + H +L +K+ + L + HIRT+YHMF+A+LI+F L+T++ D I++G ++ + L + +AFG V++ W+ M S + Y SW ++ + + +P Y + LPP S I++LE +RL MK+H+FIREN+ + S+ + YLYFLF V+ C+ Y YY+F R C+ F++ ++ +VL VF +LP LV F+ FF FLH WLNAFAEML+FGDR+FYK+WWNST+F+NYYRTWNVVVHDWLY YVYRD L + + RAAAM IVF SAV HEYVL + F FFYPVLF LF + FGMMF + + +WN+ W A+F G G+++CLYS EWYA+ CP+ T DLL PRS C Sbjct: 8 LWQKLKVEMLQQFDCQMDEFVDSVVEESSSLGGSSLNSHFSPLLSDKERAKLRYL--ELFEVDHIRTIYHMFIALLILFILSTLVVDFIDEGRLVLDFDL--LVYAFGQFPLVVVTWICMFMSALVVPYVLLHSWAVAYPTSRHRSLLTLLAGGLLLLYQGLGLGFLPTYIVLRNGLPPASRFILILEQVRLMMKVHSFIRENIQRVWSSDS-SAVPQVTPYLYFLF---------------------------VLGCLFYAYYVFVRLCIPQFRSLQLF--DLRAMVLCVFNSILPGVLVLFLGFFAFLHCWLNAFAEMLRFGDRMFYKDWWNSTSFANYYRTWNVVVHDWLYYYVYRDFLWMSQKRFRAAAMFIVFTVSAVVHEYVLAICFGFFYPVLFCLF--MCFGMMFNFILHDRRKGPVWNVIMWTALFLGQGVLICLYSQEWYAQIYCPLQEVTVSSDLLKPRSVTC 445
BLAST of O-acyltransferase vs. Ensembl Sea Lamprey
Match: soat2 (sterol O-acyltransferase 2 [Source:ZFIN;Acc:ZDB-GENE-061013-742]) HSP 1 Score: 395.586 bits (1015), Expect = 1.196e-132 Identity = 215/493 (43.61%), Postives = 298/493 (60.45%), Query Frame = 1 Query: 259 KLKEVIIEEYDEMTNETLDS--PKKLCNINLKHDMLPE------------------KQFQNRESVLTNLLNISHIRTVYHMFVAILIIFSLNTMLTDLIEKGGIIHTYHLEWVFWAFGGIGDVILLWLSMKSFTIFVYPCFLSWLYVRRMKILPISCVNKIYLVVYILTQISFVVI-----PLYFMCLIDLPPCSSAIVVLENIRLAMKIHAFIRENVAK----ELKSNELIETINFSRYLYFLFAPTLIYRDSYPKNPTIRWSYVVSNFAQVIFCIVYMYYIFARFCVVYFQNFNSIHVTMQQLVLSVFGCMLPATLVFFICFFCFLHSWLNAFAEMLQFGDRLFYKEWWNSTTFSNYYRTWNVVVHDWLYTYVYRDILLLCRFNNRAAAMTIVFLFSAVFHEYVLIVMFRFFYPVLFVLFSGVGFGMMF-----IKGRARIWNIGFWVAMFTGNGIIMCLYSMEWYARRNCPIYFSTFVDLLVPRSWFCQA 1635 KLKE I+ +++ +E ++S + I+LK + + K F R SVL L I+H+RT+YHMF+A+L++F ++T+ D I++G ++ + L + +AFG + + WL M T+ V WL R + +Y Y L +F ++ P+Y + LPP S I++LE +RL MK H+F+RENV + K + + +F+ YLYFLF PTLIYRDSYP+ PTIRW +V NFAQV+ C+ Y YY+F R C+ F+NF ++++ LVL++F C LP L+ + FF FLH WLNAFAEML+F DR+FY++WWNST+F+NYYRTWNVVVHDWLY Y YRD +AAAM VF SAV HEYVL V FFYPV+FVLF GFGM+F K ++ IWN+ W +F G GI++CLYS+EWYA+++CP TF DL+ P SW CQ Sbjct: 2 KLKEEIVHQFESKISELIESVIEESSSTIDLKSAAVLQNGGDVEKVRSLRPLSEKGKLFLPRPSVLDELFEINHVRTIYHMFIAVLMLFVISTVAVDFIDQGRLVLDFDL--LVFAFGQLPTALWAWLCMFLGTLLV----PYWLLCRWGTGYQAVHWHGLYTAYYGLLYFAFQILGLGVTPVYAVVHYSLPPASRFILILEQVRLVMKAHSFVRENVPRIMQSHCKGDSPPKLPDFNHYLYFLFCPTLIYRDSYPRTPTIRWKFVAMNFAQVLGCLFYAYYVFVRLCIPLFRNFGKEPLSIRVLVLNMFNCTLPGVLILLLAFFAFLHCWLNAFAEMLRFADRMFYQDWWNSTSFANYYRTWNVVVHDWLYYYTYRDFRWAFSGRFKAAAMFSVFSLSAVVHEYVLTVCLGFFYPVMFVLF--FGFGMLFNFVVHDKRKSPIWNVVMWTFLFIGQGIMVCLYSLEWYAQQHCPAKGETFFDLITPLSWSCQP 486
BLAST of O-acyltransferase vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004896.1 (pep scaffold:Pmarinus_7.0:GL476574:469247:474793:-1 gene:ENSPMAG00000004447.1 transcript:ENSPMAT00000004896.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 202.986 bits (515), Expect = 1.028e-61 Identity = 107/240 (44.58%), Postives = 149/240 (62.08%), Query Frame = 1 Query: 940 KNPTIRWSYVVSNFAQVIFCIVYMYYIFARFCVVYFQNFNSIHVTMQQLVLSVFGCMLPAT-----LVFFICFFCFLHSWLNAFAEMLQFGDRLFYKEWWNSTTFSNYYRTWNVVVHDWLYTYVYRDILLLCRFNNRAAAMTIVFLFSAVFHEYVLIVMFRFFYPVLFVLFSGVGFGMMFI--KGRAR-IWNIGFWVAMFTGNGIIMCLYSMEWYARRNCPIYFSTFVDLLVPRSWFCQA 1635 +NP+IRW YV + A+ ++ Y F + + FQ+ +T+++LVL V M+P L+F I FF FLH WLN F E+++F DR+FYK+WWNS +F+NYYRTWNVVVHDWLYTY Y D++ + R AAM IVF+FSA+ HEYV+ V F F PV+ LF G + F+ GR+ +WNI W A+ G G+++ LY +EW A R+CP T + + P+ W C A Sbjct: 1 RNPSIRWDYVRTKLAEAGKLWIFTQYRFTAWVMPLFQDVQREPLTLERLVLYVCHAMVPGDGPTTHLLFIITFFAFLHCWLNLFGELMRFADRMFYKDWWNSRSFANYYRTWNVVVHDWLYTYFYGDLIRVFSRRYRRAAMLIVFIFSAIVHEYVITVCFGLFCPVMLFLFICFGTMLNFLLHDGRSNDVWNIFMWFALILGQGVLVTLYFLEWSALRDCPSKPETVWEFITPQFWSCYA 240
BLAST of O-acyltransferase vs. Ensembl Sea Lamprey
Match: dgat1a (diacylglycerol O-acyltransferase 1a [Source:ZFIN;Acc:ZDB-GENE-030131-4600]) HSP 1 Score: 108.227 bits (269), Expect = 1.375e-25 Identity = 64/195 (32.82%), Postives = 107/195 (54.87%), Query Frame = 1 Query: 838 AKELKSNELIETINFSRYLYFLFAPTLIYRDSYPKNPTIRWSYVVSNFAQVIFCIVYMYYIFARFCVVYFQNFNS--IHVTMQQLVLSVFGCMLPATLVFFICFFCFLHSWLNAFAEMLQFGDRLFYKE-WWNSTTFSNYYRTWNVVVHDWLYTYVYRDILLLCRFNNRAAAMTIVFLFSAVFHEYVLIVMFRFF 1413 AK++ + +N+ YF+FAPTL Y ++P+ IR +++ +++F + M ++ V +N I + + ++V + +P L++ I F+ F HS LN AE+++FGDR FY++ WWN+ T + ++ WN+ VH W + Y+ LL R N+ A VFL SA FHEY++ V R F Sbjct: 180 AKQVAVVHYPDNLNYRDLYYFVFAPTLCYELNFPRTSRIRKRFLLRRIFEMLFLMQLMLGFIQQWIVPSIRNSMKPLIEMDVSRVVERLLKLAVPNHLIWLIFFYWFFHSCLNLLAEIMKFGDREFYRDWWWNAQTVTYFWANWNIPVHKWCVRHFYKP--LLKRGFNKMHAQLGVFLLSAFFHEYLVSVPLRMF 372
BLAST of O-acyltransferase vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001580.1 (pep scaffold:Pmarinus_7.0:GL484940:316:3318:-1 gene:ENSPMAG00000001427.1 transcript:ENSPMAT00000001580.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 67.0106 bits (162), Expect = 3.422e-13 Identity = 50/178 (28.09%), Postives = 92/178 (51.69%), Query Frame = 1 Query: 367 KQFQNRESVLTNLLNISHIRTVYHMFVAILIIFSLNTMLTDLIEKGGIIHTYHLEWVFWAFGGIGDVILLWLSMKSFTIFV-YPCFLSW------LYVRRMKIL---------PI--SCVNKIYLVVYILTQISFVVIPLYFMCLID-LPPCSSAIVVLENIRLAMKIHAFIRENVAK 843 K F+ R S+L +L ++HIRT+YH+F+A+L++ ++ +++ D++ G ++ + +V FG + V L W +M T+ V Y +W L RR L P+ ++ + Y+ + + + + + LPP S I++LE +R MK HAF+R+NV + Sbjct: 12 KVFRPRSSLLDEMLLVNHIRTIYHIFLAVLLLMAVASLILDILRHGRLLPD--ISFVISCFGKLHLVALTWGAMFVATLLVPYGALHAWARAWTLLQPRRGAPLRGWALARSSPLLAGALSAACALPYLAFVLLVLGVLPVRVSVAHALPPASRFILILEQVRFVMKAHAFVRDNVPR 187
BLAST of O-acyltransferase vs. Ensembl Yeast
Match: ARE1 (Acyl-CoA:sterol acyltransferase; endoplasmic reticulum enzyme that contributes the major sterol esterification activity in the absence of oxygen; ARE1 has a paralog, ARE2, that arose from the whole genome duplication [Source:SGD;Acc:S000000644]) HSP 1 Score: 103.219 bits (256), Expect = 1.438e-23 Identity = 73/250 (29.20%), Postives = 118/250 (47.20%), Query Frame = 1 Query: 844 ELKSNELIETINFSRYLYFLFAPTLIYRDSYPKNPTIRWSYVVSNFAQVIFCIVYMYYIFARFCV-------VYFQNFNSIH--VTMQQLVLSVFGCMLPA-TLVFFICFFCFLHSWLNAFAEMLQFGDRLFYKEWWNSTTFSNYYRTWNVVVHDWLYTYVYRDILLLCRFNNRAAAMTIVFLFSAVFHEYVLIVMFRFFYPVLFVLFSGVGF------GMMFIKGRARIWNIGFWVAMFTGNGIIMCLY 1545 + K N+ I+ S + F P L+Y+ +YP+ IRW YV+ +I I M + A+F + + F N + + Q + M+P T+++ + F+ + LN AE+ +F DR FY +WWN +F + R WNV VH +L +VY + +++ A F SAVFHE + +FR LF +F F F++ R ++ N+ F + +G IIM LY Sbjct: 361 QTKDNDFPNNISCSNFFMFCLFPVLVYQINYPRTSRIRWRYVLEKVCAIIGTIFLMM-VTAQFFMHPVAMRCIQFHNTPTFGGWIPATQEWFHLLFDMIPGFTVLYMLTFYMIWDALLNCVAELTRFADRYFYGDWWNCVSFEEFSRIWNVPVHKFLLRHVYHSSMGALHL-SKSQATLFTFFLSAVFHEMAMFAIFRRVRGYLF-MFQLSQFVWTALSNTKFLRARPQLSNVVFSFGVCSGPSIIMTLY 607
BLAST of O-acyltransferase vs. Ensembl Yeast
Match: ARE2 (Acyl-CoA:sterol acyltransferase; endoplasmic reticulum enzyme that contributes the major sterol esterification activity in the presence of oxygen; ARE2 has a paralog, ARE1, that arose from the whole genome duplication [Source:SGD;Acc:S000005302]) HSP 1 Score: 100.523 bits (249), Expect = 1.065e-22 Identity = 69/247 (27.94%), Postives = 122/247 (49.39%), Query Frame = 1 Query: 850 KSNELIETINFSRYLYFLFAPTLIYRDSYPKNPTIRWSYVVSN--------FAQVIFCIVYMYYIFARFCVVYFQNFNSIHVTMQQLVLSVFGCMLPATLVFFIC-FFCFLHSWLNAFAEMLQFGDRLFYKEWWNSTTFSNYYRTWNVVVHDWLYTYVYRDILLLCRFNNRAAAMTIVFLFSAVFHEYVLIVMFR------FFYPVLFVLFSGVGFGMMFIKGRARIWNIGFWVAMFTGNGIIMCLY 1545 ++ + I+ + +F PTLIY+ YP+ IRWSYV+ F +I + MY + R V + I + + V + ++P +V +I F+ + LN AE+ +FGDR FY +WWN +++++ R WN+ VH +L +VY + + N++ A + F S+V HE + V+F+ FF+ +L + + F++ R I N+ FW+ + G ++ LY Sbjct: 396 QTQKFPNNISAKSFFWFTMFPTLIYQIEYPRTKEIRWSYVLEKICAIFGTIFLMMIDAQILMYPVAMRALAVRNSEWTGILDRLLKWV-GLLVDIVPGFIVMYILDFYLIWDAILNCVAELTRFGDRYFYGDWWNCVSWADFSRIWNIPVHKFLLRHVYHSSMSSFKL-NKSQATLMTFFLSSVVHELAMYVIFKKLRFYLFFFQMLQMPLVALT-NTKFMRNRTIIGNVIFWLGICMGPSVMCTLY 639
BLAST of O-acyltransferase vs. Ensembl Nematostella
Match: EDO49468 (O-acyltransferase [Source:UniProtKB/TrEMBL;Acc:A7RG44]) HSP 1 Score: 388.267 bits (996), Expect = 1.131e-130 Identity = 197/403 (48.88%), Postives = 272/403 (67.49%), Query Frame = 1 Query: 391 VLTNLLNISHIRTVYHMFVAILIIFSLNTMLTDLIEKGGIIHTYHLEWVFWAFGGIGDVILLWLSMKSFTIFVYPCFLSWLYVRRMKI-LPISCVNKIYLVVYILTQISFVVIPLYFMCLIDLPPCSSAIVVLENIRLAMKIHAFIRENVAKELKSNELIETI-NFSRYLYFLFAPTLIYRDSYPKNPTIRWSYVVSNFAQVIFCIVYMYYIFARFCVVYFQNFNSIHVTMQQLVLSVFGCMLPATLVFFICFFCFLHSWLNAFAEMLQFGDRLFYKEWWNSTTFSNYYRTWNVVVHDWLYTYVYRDILLLCRFNNRAAAMTIVFLFSAVFHEYVLIVMFRFFYPVLFVLFSGVGFGMMFIKG-----RARIWNIGFWVAMFTGNGIIMCLYSMEWYARRNCP 1578 +L +LL +SH++T+Y++FVA+L +F LNT++ D I+ G + + + +FWAFG + VI +WL M ++ ++P F W + LP N ++LV YI + F V P+ + +LPP SS I++ E IRL +K+HAF+R NV K L ++E I F +YLYFLF PTL+YRD YP P IRW YVVSNF QV CI+Y YY+FARFCV F+N + L+LS F CMLP T+V + FF LHSWLNAFAEM +F DR+FYK+WWN+ +++++YRTWNVVVHDWLYTY+Y+D++ L NNR + VF+ SA+ HEYVL+ FRFF+P+LF +F GVG +F+K ++ WNI W+ +F GNG++MCLYS EWYA +NCP Sbjct: 1 MLRDLLQVSHVQTIYNIFVALLAVFVLNTVIYDFIDTGRLSLDFSI--MFWAFGKVSTVINVWLVMLIMSLLIFPLFRFWHSSQSTWYHLP----NIVWLVGYIGYIVVFCVFPIQEVYTHNLPPVSSIIILTEQIRLILKVHAFVRSNVPKVLYTSENENEIPEFGQYLYFLFCPTLVYRDHYPMTPCIRWDYVVSNFFQVAMCILYTYYVFARFCVPVFRNTGKEAGNFKNLILSAFSCMLPGTMVLVLGFFAILHSWLNAFAEMTRFADRMFYKDWWNAPSYADWYRTWNVVVHDWLYTYIYKDLVQLT--NNRNLSTVAVFVVSAIAHEYVLMFAFRFFFPILFTMFGGVGLSFVFLKPSKHNKHSQWWNIFMWITLFLGNGLLMCLYSQEWYATQNCP 395
BLAST of O-acyltransferase vs. Ensembl Nematostella
Match: EDO47288 (O-acyltransferase [Source:UniProtKB/TrEMBL;Acc:A7RML0]) HSP 1 Score: 107.842 bits (268), Expect = 4.510e-25 Identity = 78/313 (24.92%), Postives = 141/313 (45.05%), Query Frame = 1 Query: 691 VYILTQISFVVIPLYFMCLIDLPPCSSAIVVLENIRLAMKIHAFI---------------RENVAKELKSNELIE---TINFSRYLYFLFAPTLIYRDSYPKNPTIRWSYVVSNFAQVIFCIVYMYYIFARFCVVYFQNFNSIHVTMQ--QLVLSVFGCMLPATLVFFICFFCFLHSWLNAFAEMLQFGDRLFYKEWWNSTTFSNYYRTWNVVVHDWLYTYVYRDILLLCRFNNRAAAMTIVFLFSAVFHEYVLIVMFRFFYPVLFVLFSGVGFGMMFIK---GRARIWNIGFWVAMFTGNGIIMCLYSMEWY 1560 ++I + +V+P+ + PP ++ IV L +K+ ++I +ENV+ ++E + YFL PTL Y ++P+ P IR +++ + F + M + ++ V +N M+ + V +P ++ + F+C+ HS+LN E+L+F DR FYK+WWNS T +++ WN+ H W ++Y+ ++ R + A VF+ SA FHEY++ V R F G FIK N+ W ++ G + + +Y ++Y Sbjct: 135 LHIFNLMMILVVPIIVILSYKPPPWAAGIVCGAYSMLWLKLISYISVNLWHRNKLIKTSEKENVSNGKNKEPMVEYPDNLTQQDLYYFLLCPTLCYELNFPRLPAIRKRFLIRRIVEFFFLLGLMIGVAQQWIVPTIKNSIKPLQRMEYARAAERVMKLAIPNHFLWLLFFYCYFHSFLNITGELLRFADRCFYKDWWNSNTVQYFWQNWNIPAHRWAVRHLYKP--MIRRGYSNFQAQIAVFMLSAFFHEYLVSVPLRMIKLWSFSAMIGQLPMAFFIKRYIHNPNYGNVVVWCSIILGQPLAIMMYFHDYY 445
BLAST of O-acyltransferase vs. Ensembl Medaka
Match: soat1 (sterol O-acyltransferase 1 [Source:NCBI gene;Acc:101164716]) HSP 1 Score: 402.134 bits (1032), Expect = 1.307e-133 Identity = 217/506 (42.89%), Postives = 298/506 (58.89%), Query Frame = 1 Query: 172 QKINWKEKTEKKQKEFIDNVEKDMKLMFGKLKEVIIEEYDEMTNETLDSP------KKLCNINLKHDMLPEKQFQNRESVLTNLLNISHIRTVYHMFVAILIIFSLNTMLTDLIEKGGIIHTYHLEWVFWAFGGIGDVILLWLSM-KSFTIFVYPCFLSWLYVRRMKILPISCVNKIYLVVYILTQI-SFVVIPLYFMCLIDLPPCSSAIVVLENIRLAMKIHAFIRENVAKEL-----KSNELIETINFSRYLYFLFAPTLIYRDSYPKNPTIRWSYVVSNFAQVIFCIVYMYYIFARFCVVYFQNFNSIHVTMQQLVLSVFGCMLPATLVFFICFFCFLHSWLNAFAEMLQFGDRLFYKEWWNSTTFSNYYRTWNVVVHDWLYTYVYRDILLLCRFNNRAAAMTIVFLFSAVFHEYVLIVMFRFFYPVLFVLFSGVGFGMMF-----IKGRARIWNIGFWVAMFTGNGIIMCLYSMEWYARRNCPIYFSTFVDLLVPRSWFCQA 1635 +K+ K K E + + + + + + L E P KL + H K F NR S+L L + HIRT+YHMF+A+LI+F L+T++ D I++G ++ + L + +AFG V+ W+ M S + Y F W + + + ++L Q+ ++P Y + LPP S I+++E +RL MK H+F+RENV K L K++ S+YLYFLFAPTLIYRD YP+NP RWSYV SNF QV+ C+ Y YY+F R C+ F++ + + ++ +VL VF +LP LV + FF FLH WLNAFAEML+F DR+FYK+WWNST+F+NYYRTWNVVVHDWLY YVYRD LL+ + R AAM VF SAV HEY+L V F FFYPVLF LF + FGMMF + + IWN+ W A+F G G+I+CLYS EWYA+R CP+ +F++ + PRSW CQ Sbjct: 54 KKMQLKRKAEHLKNDLLRQFDSQVSDLVDHLLEESSSLERSSVPAAFSPPMSDRERAKLGHFRPPHG--EGKHFTNRRSLLDELFEVDHIRTIYHMFIALLILFILSTLVVDFIDEGRLVLDFDL--LVYAFGQFPLVVCTWMCMFLSVFLVPYTLFHLWAQSQSGSYGHPRVSSLLLGSAFLLYQVLGLGLLPAYVVVTNSLPPASCFIIIIEQVRLMMKAHSFVRENVPKVLSWAKDKTSPGPAVPQVSQYLYFLFAPTLIYRDKYPRNPVTRWSYVASNFLQVLGCLCYAYYVFVRLCIPQFRSISLQFLDLRAMVLCVFNSILPGVLVLLLAFFAFLHCWLNAFAEMLRFADRMFYKDWWNSTSFANYYRTWNVVVHDWLYYYVYRDFLLISQKRFRLAAMLFVFTISAVVHEYILAVCFGFFYPVLFCLF--MCFGMMFNFILHDRRKGPIWNVIMWTALFLGQGVIICLYSQEWYAQRYCPVKEPSFLEWVTPRSWSCQT 553
BLAST of O-acyltransferase vs. Ensembl Medaka
Match: soat2 (sterol O-acyltransferase 1 [Source:NCBI gene;Acc:101162519]) HSP 1 Score: 348.206 bits (892), Expect = 5.789e-113 Identity = 208/521 (39.92%), Postives = 302/521 (57.97%), Query Frame = 1 Query: 124 KDYENQFSDDNATKFFQKINWKEKTEKKQKEFIDNVE-KDMKLMFGKLKEVIIEEYDEMTNETLDSP---------KKLCNINLKHDMLPEKQFQNRESVLTNLLNISHIRTVYHMFVAILIIFSLNTMLTDLIEKGGIIHTYHLEWVFWAFGGIGDVILLWLSMKSFTIFV-YPCFLSWLYVRRMKILPISCVNKIYLVVYILTQISFVVIPLYFMCLIDLPPCSSAIVVLENIRLAMKIHAFIRENVAKELKS----NELIETINFSRYLYFLFAPTLIYRDSYPKNPTIRWSYVVSNFAQVIFCIVYMYYIFARFCVVYFQNFNSIHVTMQQLVLSVFGCMLPATLVFFICFFCFLHSWLNAFAEMLQFGDRLFYKEWWNSTTFSNYYRTWNVVVHDWLYTYVYRDILLLCRFNNRAAAMTIVFLFSAVFHEYVLIVMFRFFYPVLFVLFS--GVGFG-MMFIKGRARIWNIGFWVAMFTGNGIIMCLYSMEWYARRNCPIYFSTFVDLLVPRSWFCQ 1632 ++ + SDDN + + + +K KK K + V+ K ++ + +L E++ D E+ P KKL + M K F R S+L L ISHIRT+YHMF+A+L+IF L+T+ D I++G ++ + L +F+AFG + V +W M +T+ V + + W + + L+++ + + P+Y + LPP S IV+LE IR MK ++FIRE V LK+ E FS YLYFLF PTLI+R+SYP+N IRW YV F +++ C+ Y Y+I R C+ F+ + + + +VL+VF +LP ++ +CFF FLH WLN F E+L+F DR+FYK+WWNST+F+NYYRTWNVVVHDWLY Y YRD L L R RAAAM VF+ SAV HEY L + F FFYPV+F LF+ GV F M K ++ ++N+ W +F G G+ +CLY EWYA+ +CP +F ++++PRSW C Sbjct: 13 RNTKTSQSDDNFSHVGKHEDEMDKEYKKWKAYSQKVKVKILEQIQDQLGEIL----DRALAESFQPPAHLNTTAMGKKLNKQSGSQRMDDGKVFVARASLLDELFEISHIRTIYHMFIAVLLIFCLSTLAVDYIDQGRLVLEFDL--LFFAFGKLWTVTWVWAVMFLYTLSVPFYTLIFWGSLYHNSHFKLGLSLSTGLILFAVQTCILGLFPVYMVVHHQLPPASRFIVILEQIRFLMKAYSFIREVVPVILKNTPKKGETPRFPTFSSYLYFLFCPTLIFRESYPRNNQIRWKYVFVTFGKILGCLFYGYFILVRLCIPVFRPEINQPFSKRTMVLAVFNSILPGIMLLLLCFFAFLHCWLNLFGELLRFADRMFYKDWWNSTSFANYYRTWNVVVHDWLYYYGYRDFLWLSRKRFRAAAMLSVFIVSAVVHEYALAMGFGFFYPVMFCLFAVFGVAFNFTMNDKRQSPVFNVIMWACLFLGQGVQVCLYCQEWYAQIHCPRTGDSFWEIVLPRSWSCS 527
BLAST of O-acyltransferase vs. Ensembl Medaka
Match: DGAT1 (diacylglycerol O-acyltransferase 1 [Source:NCBI gene;Acc:101155899]) HSP 1 Score: 109.768 bits (273), Expect = 3.261e-25 Identity = 72/233 (30.90%), Postives = 121/233 (51.93%), Query Frame = 1 Query: 895 YFLFAPTLIYRDSYPKNPTIRWSYVVSNFAQVIFCIVYMYYIFARFCVVYFQNFNSIHVTMQ--QLVLSVFGCMLPATLVFFICFFCFLHSWLNAFAEMLQFGDRLFYKEWWNSTTFSNYYRTWNVVVHDWLYTYVYRDILLLCRFNNRAAAMTIVFLFSAVFHEYVLIVMFRFFYPVLFVLFSGVGFGMM------FIKGR---ARIWNIGFWVAMFTGNGIIMCLYSMEWY 1560 YF+ APTL Y+ ++P++ IR +++ +++F + + + ++ V QN M ++V + +P L++ I F+ F HS +N AE+LQFGDR FY++WWNS + + ++ WN+ VH W + Y+ +L R N+ A T VFL SA FHEY++ V + F F+ GMM + GR N W+++ G I + +Y ++Y Sbjct: 237 YFILAPTLCYQLNFPRSHRIRKRFLMRRLFEMLFLMQLLVGLIQQWMVPTIQNSMRPFQEMDFSRMVERLLKLAVPNHLIWLIFFYWFFHSSMNFVAELLQFGDREFYRDWWNSESVTYFWANWNIPVHKWCLRHFYKP--MLRRGINKFLAQTFVFLLSAFFHEYLVSVPLKMFRLWAFM-------GMMTQVPLAWFVGRYLNGNYGNAAVWMSLIIGQPIAVLMYVHDYY 460
BLAST of O-acyltransferase vs. Ensembl Medaka
Match: DGAT1 (diacylglycerol O-acyltransferase 1 [Source:NCBI gene;Acc:101155899]) HSP 1 Score: 109.768 bits (273), Expect = 3.775e-25 Identity = 72/233 (30.90%), Postives = 121/233 (51.93%), Query Frame = 1 Query: 895 YFLFAPTLIYRDSYPKNPTIRWSYVVSNFAQVIFCIVYMYYIFARFCVVYFQNFNSIHVTMQ--QLVLSVFGCMLPATLVFFICFFCFLHSWLNAFAEMLQFGDRLFYKEWWNSTTFSNYYRTWNVVVHDWLYTYVYRDILLLCRFNNRAAAMTIVFLFSAVFHEYVLIVMFRFFYPVLFVLFSGVGFGMM------FIKGR---ARIWNIGFWVAMFTGNGIIMCLYSMEWY 1560 YF+ APTL Y+ ++P++ IR +++ +++F + + + ++ V QN M ++V + +P L++ I F+ F HS +N AE+LQFGDR FY++WWNS + + ++ WN+ VH W + Y+ +L R N+ A T VFL SA FHEY++ V + F F+ GMM + GR N W+++ G I + +Y ++Y Sbjct: 254 YFILAPTLCYQLNFPRSHRIRKRFLMRRLFEMLFLMQLLVGLIQQWMVPTIQNSMRPFQEMDFSRMVERLLKLAVPNHLIWLIFFYWFFHSSMNFVAELLQFGDREFYRDWWNSESVTYFWANWNIPVHKWCLRHFYKP--MLRRGINKFLAQTFVFLLSAFFHEYLVSVPLKMFRLWAFM-------GMMTQVPLAWFVGRYLNGNYGNAAVWMSLIIGQPIAVLMYVHDYY 477
BLAST of O-acyltransferase vs. Ensembl Medaka
Match: dgat1b (diacylglycerol O-acyltransferase 1 [Source:NCBI gene;Acc:101166984]) HSP 1 Score: 108.997 bits (271), Expect = 7.385e-25 Identity = 65/228 (28.51%), Postives = 121/228 (53.07%), Query Frame = 1 Query: 895 YFLFAPTLIYRDSYPKNPTIRWSYVVSNFAQVIFCIVYMYYIFARFCVVYFQNFNSI--HVTMQQLVLSVFGCMLPATLVFFICFFCFLHSWLNAFAEMLQFGDRLFYKEWWNSTTFSNYYRTWNVVVHDWLYTYVYRDILLLCRFNNRAAAMTIVFLFSAVFHEYVLIVMFRFF----YPVLFVLFSGVGFGMMFIKGRARIWNIGFWVAMFTGNGIIMCLYSMEWY 1560 YF+FAPTL Y ++P++P IR S+++ ++ F I + + ++ + Q+ + + ++ + +P L++ + F+ F HS +N AE+L+FGDR FYK+WWNS + + +++ WN+ VH W + Y+ LL + ++ A+ + VF SA FHEY++ V R F + + F F++G N W+++ G + +Y ++Y Sbjct: 270 YFVFAPTLCYELNFPRSPEIRMSFLLRRLFEMFFFIQVLVGLTQQWMIPIIQSSMKPLEDMDLSRMTERLLRLAVPNHLLWLMFFYWFFHSSMNFTAELLRFGDRQFYKDWWNSESVTYFWQNWNIPVHKWCLRHFYKP--LLRKGFSKIASQSAVFFLSAFFHEYLVSVPLRMFRLWAFTGMMAQLPLAWFVGRFLRG--NYGNAAVWISIIIGQPFAVLMYVHDYY 493
BLAST of O-acyltransferase vs. Planmine SMEST
Match: SMESG000000989.1 (SMESG000000989.1) HSP 1 Score: 322.398 bits (825), Expect = 7.885e-104 Identity = 175/445 (39.33%), Postives = 267/445 (60.00%), Query Frame = 1 Query: 355 MLPEKQFQNRESVLTNLLNISHIRTVYHMFVAILIIFSLNTMLTDLIEKGGIIHTYHLEWVFWAFGGIGDVILLWLSMKSFTIFVYPCFLSWLYVRRMKILPISCVNKIYLVVYILTQISFVVIPLYFMCLIDLPPCSSAIVVLENIRLAMKIHAFIRENVAK-----------ELKSNELIETINFSRYLYFLFAPTLIYRDSYPKNPTIRWSYVVSNFAQVIFCIVYMYYIFARFCVVYFQNFNSIHVTMQQLVLSVFGCMLPATLVFFICFFCFLHSWLNAFAEMLQFGDRLFYKEWWNSTTFSNYYRTWNVVVHDWLYTYVYRDI-LLLCRFNN-----RAAAMTIVFLFSAVFHEYVLIVMFRFFYPVLFVLFSGVGFGMMFIKGR--ARIWNIGFWVAMFTGNGIIMCLYSMEWYARRNCPIYFSTFVDLLVPRSWFCQ 1632 ++ E+ + NR+S+LT + I H ++ +MF++ +I+ + T+ D +++G H +H +WV F GI V+L L++ I + W+ +R +K + ++ + +Y+L VV+P+ + +PPCSSA +V E IR+ MKIHA++R + K ++ + E + + ++LYFL PTLIYRDSYP ++ + V+S+F + I CI++MYYIF F +FN +T++ ++ F +LP L+ FFCFLHSWLNAFAE+ +FGDR FYK+WWN+T+ S+Y+RTWN +++DWLYTY+YRD LL+ R N ++ M V L SA+ HEYVL FRFFYPVL +F G + F+K +RI NI W ++ GN + LYS EWYAR+NC F+D +VPRS FC+ Sbjct: 28 LVRERVYVNRDSLLTEMFRIPHFNSLLNMFLSFVILMMMKTVCNDWLKEGFFKHYHHFQWVSNEFAGIQIVLLTLLALYILVILSFLLVKFWIRMR-LKWKLKALLDVFSVFIYLLIIGCAVVVPVQIVMNHYVPPCSSAFIVYEQIRILMKIHAYVRTVIPKLHHLFKQSNQHDIIQKSINEVVCWKKFLYFLIIPTLIYRDSYPMRKSVNFKSVISSFLEFILCIIFMYYIFINLMRPIFHDFNPSFMTLEVIIPKFFQAILPTILMMLSVFFCFLHSWLNAFAELTKFGDRQFYKDWWNATSLSDYFRTWNALIYDWLYTYIYRDFSLLMLRITNNKMISKSFGMISVLLISALVHEYVLAFCFRFFYPVLLTVFFFSGTVLYFVKANRASRIPNIMLWTGLYIGNSMFTTLYSSEWYARKNCKRTNEGFLDFIVPRSLFCE 471
BLAST of O-acyltransferase vs. Planmine SMEST
Match: SMESG000000988.1 (SMESG000000988.1) HSP 1 Score: 320.472 bits (820), Expect = 3.359e-103 Identity = 178/444 (40.09%), Postives = 271/444 (61.04%), Query Frame = 1 Query: 358 LPEKQFQNRESVLTNLLNISHIRTVYHMFVAILIIFSLNTMLTDLIEKGGIIHTYHLEWVFWAFGGIGDVILLWLSMKSFTIFVYPCFLSWLYVRRMKILPISCVNKIYLVVYILTQISFVVIPLYFMCLIDLPPCSSAIVVLENIRLAMKIHAFIRENVAKE----LKSNE---LIETIN----FSRYLYFLFAPTLIYRDSYPKNPTIRWSYVVSNFAQVIFCIVYMYYIFARFCVVYFQNFNSIHVTMQQLVLSVFGCMLPATLVFFICFFCFLHSWLNAFAEMLQFGDRLFYKEWWNSTTFSNYYRTWNVVVHDWLYTYVYRDI-LLLCRFNN-----RAAAMTIVFLFSAVFHEYVLIVMFRFFYPVLFVLFSGVGFGMMFIKGR--ARIWNIGFWVAMFTGNGIIMCLYSMEWYARRNCPIYFSTFVDLLVPRSWFCQ 1632 +PE+ + +R+S+LT + I H ++ +MF++ +I+ + T+ D +++G H +H +WV F GI V+L L++ I + W+ +R +K + ++ + +Y+L VV+P+ + +PPCSS +V E IR+ MKIHA++R + K +SN+ L ++IN + ++LYFL PTLIYRDSYP ++ + V+S+F + I CI++MYYIF F +FN +T++ ++ F +LP L+ FFCFLHSWLNAFAE+ +FGDR FYK+WWN+T+ S+Y+RTWN +++DWLYTY+YRD LL+ R N ++ M V L SA+ HEYVL FRFFYPVL +F G + F+K +RI NI W ++ GN + + LYS EWYAR+NC F+D +VPRS FC+ Sbjct: 29 VPERVYVDRDSLLTEMFRIPHFNSLLNMFLSFVILMMMKTVCNDWLKEGFFKHYHHFQWVSNEFAGIQIVLLTLLALYILVILSFLLVKFWIRMR-LKWKLKALLDVFSVFIYLLIIGCAVVVPVQIVMNHYVPPCSSIFIVYEQIRILMKIHAYVRTVIPKLHHLFKQSNQHDILQKSINGVVCWEKFLYFLIIPTLIYRDSYPMRKSVNFKSVISSFLEFILCIIFMYYIFINLMRPIFHDFNPSFMTLEVIIPKFFQAILPTILMMLSVFFCFLHSWLNAFAELTKFGDRQFYKDWWNATSLSDYFRTWNALIYDWLYTYIYRDFSLLMLRITNNKMISKSFGMISVLLISALVHEYVLAFCFRFFYPVLLTVFFFSGTVLYFVKANRASRIPNIMLWTGLYIGNSMFVTLYSSEWYARKNCKRTNERFLDFIVPRSLFCE 471
BLAST of O-acyltransferase vs. Planmine SMEST
Match: SMESG000037749.1 (SMESG000037749.1) HSP 1 Score: 255.373 bits (651), Expect = 1.474e-82 Identity = 124/126 (98.41%), Postives = 126/126 (100.00%), Query Frame = 1 Query: 67 MTSLDGEIRNRRINETGIVKDYENQFSDDNATKFFQKINWKEKTEKKQKEFIDNVEKDMKLMFGKLKEVIIEEYDEMTNETLDSPKKLCNINLKHDMLPEKQFQNRESVLTNLLNISHIRTVYHMF 444 MTSLDGEIRNRRIN+TGIVKDYENQFSDDNATKFFQKINWKEKTEKKQKEFIDNVEKDMKLMFGKLKEVIIEEYDEMTNETLDSPKKLCNINLKHDMLPEKQFQNRESVLTNLLNISHIRTVYH+F Sbjct: 1 MTSLDGEIRNRRINDTGIVKDYENQFSDDNATKFFQKINWKEKTEKKQKEFIDNVEKDMKLMFGKLKEVIIEEYDEMTNETLDSPKKLCNINLKHDMLPEKQFQNRESVLTNLLNISHIRTVYHIF 126 HSP 2 Score: 55.8398 bits (133), Expect = 4.531e-9 Identity = 27/44 (61.36%), Postives = 32/44 (72.73%), Query Frame = 3 Query: 429 SLSHVRCYFDYIFP*HNAYRFNRKRWNNSYLSFRMGILGIWWNR 560 ++SH+R + + FNRKRWNNSYLSFRMGILGIWWNR Sbjct: 115 NISHIRTVY---------HIFNRKRWNNSYLSFRMGILGIWWNR 149
BLAST of O-acyltransferase vs. Planmine SMEST
Match: SMESG000024271.1 (SMESG000024271.1) HSP 1 Score: 119.013 bits (297), Expect = 3.349e-28 Identity = 76/243 (31.28%), Postives = 123/243 (50.62%), Query Frame = 1 Query: 868 ETINFSRYLYFLFAPTLIYRDSYPKNPTIRWSYVVSN------FAQVIFCIVYMYYI-FARFCVVYFQNFNSIHVTMQQLVLSVFGCMLPATLVFFICFFCFLHSWLNAFAEMLQFGDRLFYKEWWNSTTFSNYYRTWNVVVHDWLYTYVYRDILLLCRFNNRAAAMTIVFLFSAVFHEYVLIVMFRFFYPVLFVLFSG-VGFGMMFIK--GRARIWNIGFWVAMFTGNGIIMCLYSMEWYAR 1566 + +N YF+ APTL Y ++P+ IR ++ Q++FC++ + + V F N + V + L LS+ P L++ + F+ HS LN AE+L FGDRLFYK+WWN+ T + ++ TWN+ VH W +++ + LL R + A +VF SA FHE+++ V R F F G V F M K R++ N W+++ G + M +Y ++Y + Sbjct: 270 DNLNLKDLYYFIVAPTLCYELNFPRTLKIRKKFLWKRTLELIFLPQLVFCLIQQWILPLLHNSVTPFSNSHFSVVLERMLKLSI-----PNHLIWLMLFYAMFHSGLNVCAELLYFGDRLFYKDWWNANTVTEFWSTWNIPVHRWARRHIF--MPLLKRKYTKLTASVVVFFISAFFHEFLVSVPLRMFRLWSFTAMIGQVPFAMFVSKYLKRSQAGNFAVWISLIIGQPLAMMMYFHDYYVQ 505
BLAST of O-acyltransferase vs. Planmine SMEST
Match: SMESG000024271.1 (SMESG000024271.1) HSP 1 Score: 118.627 bits (296), Expect = 3.727e-28 Identity = 76/243 (31.28%), Postives = 123/243 (50.62%), Query Frame = 1 Query: 868 ETINFSRYLYFLFAPTLIYRDSYPKNPTIRWSYVVSN------FAQVIFCIVYMYYI-FARFCVVYFQNFNSIHVTMQQLVLSVFGCMLPATLVFFICFFCFLHSWLNAFAEMLQFGDRLFYKEWWNSTTFSNYYRTWNVVVHDWLYTYVYRDILLLCRFNNRAAAMTIVFLFSAVFHEYVLIVMFRFFYPVLFVLFSG-VGFGMMFIK--GRARIWNIGFWVAMFTGNGIIMCLYSMEWYAR 1566 + +N YF+ APTL Y ++P+ IR ++ Q++FC++ + + V F N + V + L LS+ P L++ + F+ HS LN AE+L FGDRLFYK+WWN+ T + ++ TWN+ VH W +++ + LL R + A +VF SA FHE+++ V R F F G V F M K R++ N W+++ G + M +Y ++Y + Sbjct: 255 DNLNLKDLYYFIVAPTLCYELNFPRTLKIRKKFLWKRTLELIFLPQLVFCLIQQWILPLLHNSVTPFSNSHFSVVLERMLKLSI-----PNHLIWLMLFYAMFHSGLNVCAELLYFGDRLFYKDWWNANTVTEFWSTWNIPVHRWARRHIF--MPLLKRKYTKLTASVVVFFISAFFHEFLVSVPLRMFRLWSFTAMIGQVPFAMFVSKYLKRSQAGNFAVWISLIIGQPLAMMMYFHDYYVQ 490 The following BLAST results are available for this feature:
BLAST of O-acyltransferase vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of O-acyltransferase vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of O-acyltransferase vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of O-acyltransferase vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of O-acyltransferase vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of O-acyltransferase vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of O-acyltransferase vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of O-acyltransferase vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of O-acyltransferase vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of O-acyltransferase vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 4
BLAST of O-acyltransferase vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 2
BLAST of O-acyltransferase vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 2
BLAST of O-acyltransferase vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of O-acyltransferase vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30008540 ID=SMED30008540|Name=O-acyltransferase|organism=Schmidtea mediterranea sexual|type=transcript|length=1770bpback to top protein sequence of SMED30008540-orf-1 >SMED30008540-orf-1 ID=SMED30008540-orf-1|Name=SMED30008540-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=524bp MTSLDGEIRNRRINETGIVKDYENQFSDDNATKFFQKINWKEKTEKKQKEback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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