SOXP-3

Overview


Name	SOXP-3 (AFD29621.1)
Smed ID	SMED30008505
Length (bp)	1052

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of SOXP-3 (SMED30008505) t-SNE clustered cells

Violin plots show distribution of expression levels for SOXP-3 (SMED30008505) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of SOXP-3 (SMED30008505) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for SOXP-3 (SMED30008505) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30008505

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 28

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
zeta neoblast	SMED30008505	h1SMcG0009867	SMED30008505	smed_20140614	PMID:29906446 Zeng et al., 2018
pigment cell	SMED30008505	h1SMcG0009867	SmedASXL_004704	SmedAsxl_ww_GCZZ01	PMID:29158443 He et al., 2017
Category 2 cell	SMED30008505	h1SMcG0009867	SmedASXL_004704	SmedAsxl_ww_GCZZ01	PMID:26114597 Zhu et al., 2015
X1 cell	SMED30008505	h1SMcG0009867	SmedASXL_004704	SmedAsxl_ww_GCZZ01	PMID:26114597 Zhu et al., 2015
X2 cell	SMED30008505	h1SMcG0009867	SmedASXL_004704	SmedAsxl_ww_GCZZ01	PMID:26114597 Zhu et al., 2015
parenchyma	SMED30008505	h1SMcG0009867	SmedASXL_004704	SmedAsxl_ww_GCZZ01	PMID:26114597 Zhu et al., 2015
Category 2 cell	SMED30008505	h1SMcG0009867	SMED30008505	smed_20140614	PMID:29100657 Cheng et al., 2018
Category 3 cell	SMED30008505	h1SMcG0009867	SMED30008505	smed_20140614	PMID:29100657 Cheng et al., 2018
neoblast	SMED30008505	h1SMcG0009867	SMED30008505	smed_20140614	PMID:29100657 Cheng et al., 2018
X1 cell	SMED30008505	h1SMcG0009867	SMED30008505	smed_20140614	PMID:29100657 Cheng et al., 2018
Smed sexual biotype	SMED30008505	h1SMcG0009867	Contig42468	newmark_ests	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30008505	h1SMcG0009867	Contig42468	uc_Smed_v2	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30008505	h1SMcG0009867	Contig29804	uc_Smed_v2	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30008505	h1SMcG0009867	Contig29804	newmark_ests	PMID:29674431 Fincher et al., 2018
epidermis	SMED30008505	h1SMcG0009867	dd_Smed_v4_5942_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cephalic ganglia	SMED30008505	h1SMcG0009867	dd_Smed_v4_5942_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
neoblast	SMED30008505	h1SMcG0009867	dd_Smed_v4_5942_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
zeta neoblast	SMED30008505	h1SMcG0009867	SMED30008505	smed_20140614	PMID:30194301 Mihaylova et al., 2018
zeta neoblast	SMED30008505	h1SMcG0009867	JQ425153.1	smed_ncbi_20240424	PMID:30194301 Mihaylova et al., 2018
zeta neoblast	SMED30008505	h1SMcG0009867	JQ425153	smed_ncbi_20240424	PMID:25017721 van Wolfswinkel et al., 2014
zeta neoblast	SMED30008505	h1SMcG0009867	JQ425153	smed_ncbi_20240424	PMID:25017721 van Wolfswinkel et al., 2014
Category 2 cell	SMED30008505	h1SMcG0009867	dd_Smed_v6_5942_0	dd_Smed_v6	PMID:29674432 Plass et al., 2018
Category 2 cell	SMED30008505	h1SMcG0009867	dd_Smed_v4_5942_0_1	dd_Smed_v4	PMID:28292427 Wurtzel et al., 2017
neoblast	SMED30008505	h1SMcG0009867	SmWIOct06_030341	GPL14150_gene_models	PMID:22385657 Wagner et al., 2012
neoblast	SMED30008505	h1SMcG0009867	SMED_05061_V2_1	GPL14150	PMID:22385657 Wagner et al., 2012
neoblast	SMED30008505	h1SMcG0009867	SMED_05061_V2_1	GPL14150_gene_models	PMID:22385657 Wagner et al., 2012
neoblast	SMED30008505	h1SMcG0009867	SMED30008505	smed_20140614	PMID:22385657 Wagner et al., 2012
neoblast	SMED30008505	h1SMcG0009867	SMED30008505	smed_20140614	PMID:22385657 Wagner et al., 2012

Note: Hover over icons to view figure legend

Homology

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BLAST of SOXP-3 vs. Ensembl Human
Match: SOX11 (SRY-box transcription factor 11 [Source:HGNC Symbol;Acc:HGNC:11191])

HSP 1 Score: 91.2781 bits (225), Expect = 9.085e-20
Identity = 37/73 (50.68%), Postives = 53/73 (72.60%), Query Frame = 1

Query:  433 SNHIKIPMNAFMVWAKINRKLMASQYPNFSNLDISKLLGKKWNEMSAEERTPFINEAKQLRIEHLNQYPEFRY 651
            S HIK PMNAFMVW+KI R+ +  Q P+  N +ISK LGK+W  +   E+ PFI EA++LR++H+  YP+++Y
Sbjct:   46 SGHIKRPMNAFMVWSKIERRKIMEQSPDMHNAEISKRLGKRWKMLKDSEKIPFIREAERLRLKHMADYPDYKY 118

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BLAST of SOXP-3 vs. Ensembl Human
Match: SOX8 (SRY-box transcription factor 8 [Source:HGNC Symbol;Acc:HGNC:11203])

HSP 1 Score: 90.8929 bits (224), Expect = 1.216e-19
Identity = 35/77 (45.45%), Postives = 55/77 (71.43%), Query Frame = 1

Query:  421 SVKNSNHIKIPMNAFMVWAKINRKLMASQYPNFSNLDISKLLGKKWNEMSAEERTPFINEAKQLRIEHLNQYPEFRY 651
            ++K   H+K PMNAFMVWA+  R+ +A QYP+  N ++SK LGK W  +S  E+ PF+ EA++LR++H   +P+++Y
Sbjct:   95 ALKAKPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLSESEKRPFVEEAERLRVQHKKDHPDYKY 171

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BLAST of SOXP-3 vs. Ensembl Human
Match: SOX9 (SRY-box transcription factor 9 [Source:HGNC Symbol;Acc:HGNC:11204])

HSP 1 Score: 91.2781 bits (225), Expect = 1.463e-19
Identity = 36/77 (46.75%), Postives = 55/77 (71.43%), Query Frame = 1

Query:  421 SVKNSNHIKIPMNAFMVWAKINRKLMASQYPNFSNLDISKLLGKKWNEMSAEERTPFINEAKQLRIEHLNQYPEFRY 651
            S KN  H+K PMNAFMVWA+  R+ +A QYP+  N ++SK LGK W  ++  E+ PF+ EA++LR++H   +P+++Y
Sbjct:   98 SSKNKPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLNESEKRPFVEEAERLRVQHKKDHPDYKY 174

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BLAST of SOXP-3 vs. Ensembl Human
Match: SOX14 (SRY-box transcription factor 14 [Source:HGNC Symbol;Acc:HGNC:11193])

HSP 1 Score: 87.8113 bits (216), Expect = 1.560e-19
Identity = 36/75 (48.00%), Postives = 55/75 (73.33%), Query Frame = 1

Query:  427 KNSNHIKIPMNAFMVWAKINRKLMASQYPNFSNLDISKLLGKKWNEMSAEERTPFINEAKQLRIEHLNQYPEFRY 651
            K S+HIK PMNAFMVW++  R+ MA + P   N +ISK LG +W  +S  E+ P+I+EAK+LR +H+ ++P+++Y
Sbjct:    3 KPSDHIKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSEAEKRPYIDEAKRLRAQHMKEHPDYKY 77

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BLAST of SOXP-3 vs. Ensembl Human
Match: SOX18 (SRY-box transcription factor 18 [Source:HGNC Symbol;Acc:HGNC:11194])

HSP 1 Score: 90.1225 bits (222), Expect = 1.635e-19
Identity = 36/79 (45.57%), Postives = 56/79 (70.89%), Query Frame = 1

Query:  415 KKSVKNSNHIKIPMNAFMVWAKINRKLMASQYPNFSNLDISKLLGKKWNEMSAEERTPFINEAKQLRIEHLNQYPEFRY 651
            ++   + + I+ PMNAFMVWAK  RK +A Q P+  N  +SK+LGK W E++A E+ PF+ EA++LR++HL  +P ++Y
Sbjct:   76 ERQAADESRIRRPMNAFMVWAKDERKRLAQQNPDLHNAVLSKMLGKAWKELNAAEKRPFVEEAERLRVQHLRDHPNYKY 154

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BLAST of SOXP-3 vs. Ensembl Celegans
Match: sox-3 (SOX (Mammalian SRY box) family [Source:UniProtKB/TrEMBL;Acc:Q20201])

HSP 1 Score: 87.4261 bits (215), Expect = 4.810e-20
Identity = 42/95 (44.21%), Postives = 67/95 (70.53%), Query Frame = 1

Query:  436 NHIKIPMNAFMVWAKINRKLMASQYPNFSNLDISKLLGKKWNEMSAEERTPFINEAKQLRIEHLNQYPEFRYXXXXXXXXXXXXXXIKTDLASPT 720
            +H+K PMNAFMVW++  R+ MA   P   N +ISK LG +W ++S +E+ PFI+EAK+LR  H+ ++P+++Y+PRR+ K S   +  + ++A PT
Sbjct:   46 DHVKRPMNAFMVWSRGQRRKMAQDNPKMHNSEISKRLGAEWKQLSEQEKRPFIDEAKRLRALHMKEHPDYKYRPRRKPKSSNLKQQPRLNIAMPT 140

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BLAST of SOXP-3 vs. Ensembl Celegans
Match: sox-2 (Transcription factor sox-2 [Source:UniProtKB/Swiss-Prot;Acc:Q21305])

HSP 1 Score: 87.0409 bits (214), Expect = 2.406e-19
Identity = 37/79 (46.84%), Postives = 55/79 (69.62%), Query Frame = 1

Query:  415 KKSVKNSNHIKIPMNAFMVWAKINRKLMASQYPNFSNLDISKLLGKKWNEMSAEERTPFINEAKQLRIEHLNQYPEFRY 651
            K   KN + +K PMNAFMVW++  RK MA + P   N +ISK LG +W  +S +E+ PFI+EAK+LR  H+ ++P+++Y
Sbjct:   51 KDGKKNDDRVKRPMNAFMVWSRGQRKKMALENPKMHNSEISKRLGTEWKMLSEQEKRPFIDEAKRLRAIHMKEHPDYKY 129

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Query:  415 KKSVKNSNHIKIPMNAFMVWAKINRKLMASQYPNFSNLDISKLLGKKWNEMSAEERTPFINEAKQLRIEHLNQYPEFRY 651
            K   KN + +K PMNAFMVW++  RK MA + P   N +ISK LG +W  +S +E+ PFI+EAK+LR  H+ ++P+++Y
Sbjct:   51 KDGKKNDDRVKRPMNAFMVWSRGQRKKMALENPKMHNSEISKRLGTEWKMLSEQEKRPFIDEAKRLRAIHMKEHPDYKY 129

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Query:  415 KKSVKNSNHIKIPMNAFMVWAKINRKLMASQYPNFSNLDISKLLGKKWNEMSAEERTPFINEAKQLRIEHLNQYPEFRY 651
            K   KN + +K PMNAFMVW++  RK MA + P   N +ISK LG +W  +S +E+ PFI+EAK+LR  H+ ++P+++Y
Sbjct:   51 KDGKKNDDRVKRPMNAFMVWSRGQRKKMALENPKMHNSEISKRLGTEWKMLSEQEKRPFIDEAKRLRAIHMKEHPDYKY 129

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BLAST of SOXP-3 vs. Ensembl Celegans
Match: sem-2 (Transcription factor sem-2 [Source:UniProtKB/Swiss-Prot;Acc:Q8T3B9])

HSP 1 Score: 87.8113 bits (216), Expect = 4.706e-19
Identity = 34/72 (47.22%), Postives = 53/72 (73.61%), Query Frame = 1

Query:  427 KNSNHIKIPMNAFMVWAKINRKLMASQYPNFSNLDISKLLGKKWNEMSAEERTPFINEAKQLRIEHLNQYPE 642
            K+SNHIK PMNAFMVW+++ R+ +    P+  N +ISK LG +W  ++ EE+ PF+ EA++LR+ H+ +YP+
Sbjct:   88 KSSNHIKRPMNAFMVWSQMERRKICEHQPDMHNAEISKQLGSRWRSLTDEEKAPFVAEAERLRVCHMQEYPD 159

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BLAST of SOXP-3 vs. Ensembl Fly
Match: Sox15 (gene:FBgn0005613 transcript:FBtr0087576)

HSP 1 Score: 93.9745 bits (232), Expect = 1.219e-20
Identity = 38/78 (48.72%), Postives = 58/78 (74.36%), Query Frame = 1

Query:  418 KSVKNSNHIKIPMNAFMVWAKINRKLMASQYPNFSNLDISKLLGKKWNEMSAEERTPFINEAKQLRIEHLNQYPEFRY 651
            KS K S  I+ PMNAFMVWAKI RK +A + P+  N D+SK+LGKKW  ++ ++R P++ EA++LR+ H+ ++P ++Y
Sbjct:  208 KSAKESR-IRRPMNAFMVWAKIERKKLADENPDLHNADLSKMLGKKWRSLTPQDRRPYVEEAERLRVIHMTEHPNYKY 284

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BLAST of SOXP-3 vs. Ensembl Fly
Match: Sox21b (gene:FBgn0042630 transcript:FBtr0330116)

HSP 1 Score: 88.1965 bits (217), Expect = 8.628e-19
Identity = 37/84 (44.05%), Postives = 59/84 (70.24%), Query Frame = 1

Query:  400 FKDITKKSVKNSNHIKIPMNAFMVWAKINRKLMASQYPNFSNLDISKLLGKKWNEMSAEERTPFINEAKQLRIEHLNQYPEFRY 651
             ++ TK+  +N  HIK PMNAFMVW+++ R+ +A   P   N +ISK LG +W  ++ EE+ PFI+EAK+LR  H+ ++P+++Y
Sbjct:  236 IQNTTKR--QNEEHIKRPMNAFMVWSRLQRRKIAQDNPKMHNSEISKRLGAEWKLLTEEEKRPFIDEAKRLRAMHMKEHPDYKY 317

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BLAST of SOXP-3 vs. Ensembl Fly
Match: Sox21b (gene:FBgn0042630 transcript:FBtr0075747)

HSP 1 Score: 87.8113 bits (216), Expect = 9.248e-19
Identity = 37/84 (44.05%), Postives = 59/84 (70.24%), Query Frame = 1

Query:  400 FKDITKKSVKNSNHIKIPMNAFMVWAKINRKLMASQYPNFSNLDISKLLGKKWNEMSAEERTPFINEAKQLRIEHLNQYPEFRY 651
             ++ TK+  +N  HIK PMNAFMVW+++ R+ +A   P   N +ISK LG +W  ++ EE+ PFI+EAK+LR  H+ ++P+++Y
Sbjct:  236 IQNTTKR--QNEEHIKRPMNAFMVWSRLQRRKIAQDNPKMHNSEISKRLGAEWKLLTEEEKRPFIDEAKRLRAMHMKEHPDYKY 317

[Close]

BLAST of SOXP-3 vs. Ensembl Fly
Match: Sox21b (gene:FBgn0042630 transcript:FBtr0330115)

HSP 1 Score: 87.8113 bits (216), Expect = 9.248e-19
Identity = 37/84 (44.05%), Postives = 59/84 (70.24%), Query Frame = 1

Query:  400 FKDITKKSVKNSNHIKIPMNAFMVWAKINRKLMASQYPNFSNLDISKLLGKKWNEMSAEERTPFINEAKQLRIEHLNQYPEFRY 651
             ++ TK+  +N  HIK PMNAFMVW+++ R+ +A   P   N +ISK LG +W  ++ EE+ PFI+EAK+LR  H+ ++P+++Y
Sbjct:  236 IQNTTKR--QNEEHIKRPMNAFMVWSRLQRRKIAQDNPKMHNSEISKRLGAEWKLLTEEEKRPFIDEAKRLRAMHMKEHPDYKY 317

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BLAST of SOXP-3 vs. Ensembl Fly
Match: SoxN (gene:FBgn0029123 transcript:FBtr0079733)

HSP 1 Score: 87.4261 bits (215), Expect = 1.340e-18
Identity = 35/78 (44.87%), Postives = 57/78 (73.08%), Query Frame = 1

Query:  418 KSVKNSNHIKIPMNAFMVWAKINRKLMASQYPNFSNLDISKLLGKKWNEMSAEERTPFINEAKQLRIEHLNQYPEFRY 651
            K+ ++++ +K PMNAFMVW++  R+ MAS  P   N +ISK LG +W ++S  E+ PFI+EAK+LR  H+ ++P+++Y
Sbjct:  171 KNQQHADRVKRPMNAFMVWSRGQRRKMASDNPKMHNSEISKRLGAQWKDLSESEKRPFIDEAKRLRAVHMKEHPDYKY 248

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BLAST of SOXP-3 vs. Ensembl Zebrafish
Match: sox8a (SRY-box transcription factor 8a [Source:ZFIN;Acc:ZDB-GENE-130530-719])

HSP 1 Score: 94.3597 bits (233), Expect = 4.061e-21
Identity = 37/78 (47.44%), Postives = 57/78 (73.08%), Query Frame = 1

Query:  418 KSVKNSNHIKIPMNAFMVWAKINRKLMASQYPNFSNLDISKLLGKKWNEMSAEERTPFINEAKQLRIEHLNQYPEFRY 651
            +S+K+  H+K PMNAFMVWA+  R+ +A QYP+  N ++SK LGK W  +S  E+ PF+ EA++LR++H   YP+++Y
Sbjct:   78 RSLKDKPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLSESEKRPFVEEAERLRLQHKKDYPDYKY 155

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BLAST of SOXP-3 vs. Ensembl Zebrafish
Match: sox9a (SRY-box transcription factor 9a [Source:ZFIN;Acc:ZDB-GENE-001103-1])

HSP 1 Score: 89.3521 bits (220), Expect = 2.847e-20
Identity = 36/77 (46.75%), Postives = 55/77 (71.43%), Query Frame = 1

Query:  421 SVKNSNHIKIPMNAFMVWAKINRKLMASQYPNFSNLDISKLLGKKWNEMSAEERTPFINEAKQLRIEHLNQYPEFRY 651
            S KN  H+K PMNAFMVWA+  R+ +A QYP+  N ++SK LGK W  ++  E+ PF+ EA++LR++H   +P+++Y
Sbjct:  100 SSKNKPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLNEVEKRPFVEEAERLRVQHKKDHPDYKY 176

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BLAST of SOXP-3 vs. Ensembl Zebrafish
Match: sox8b (SRY-box transcription factor 8b [Source:ZFIN;Acc:ZDB-GENE-031114-1])

HSP 1 Score: 90.1225 bits (222), Expect = 9.348e-20
Identity = 35/77 (45.45%), Postives = 55/77 (71.43%), Query Frame = 1

Query:  421 SVKNSNHIKIPMNAFMVWAKINRKLMASQYPNFSNLDISKLLGKKWNEMSAEERTPFINEAKQLRIEHLNQYPEFRY 651
            S K+  H+K PMNAFMVWA+  R+ +A QYP+  N ++SK LGK W  ++  E+ PF+ EA++LR++H   +P+++Y
Sbjct:   79 SGKSKPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLTESEKRPFVEEAERLRVQHKKDHPDYKY 155

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BLAST of SOXP-3 vs. Ensembl Zebrafish
Match: sox12 (SRY-box transcription factor 12 [Source:ZFIN;Acc:ZDB-GENE-040724-33])

HSP 1 Score: 89.3521 bits (220), Expect = 1.735e-19
Identity = 35/73 (47.95%), Postives = 54/73 (73.97%), Query Frame = 1

Query:  433 SNHIKIPMNAFMVWAKINRKLMASQYPNFSNLDISKLLGKKWNEMSAEERTPFINEAKQLRIEHLNQYPEFRY 651
            + HIK PMNAFMVW++I R+ +  Q+P+  N +ISK LGK+W  +   E+ PFI EA++LR++H+  YP+++Y
Sbjct:   50 TGHIKRPMNAFMVWSQIERRKIMEQWPDMHNAEISKRLGKRWKLLPDYEKIPFIKEAERLRLKHMADYPDYKY 122

[Close]

BLAST of SOXP-3 vs. Ensembl Zebrafish
Match: sox4b (SRY-box transcription factor 4b [Source:ZFIN;Acc:ZDB-GENE-040426-1274])

HSP 1 Score: 88.9669 bits (219), Expect = 1.767e-19
Identity = 41/98 (41.84%), Postives = 67/98 (68.37%), Query Frame = 1

Query:  433 SNHIKIPMNAFMVWAKINRKLMASQYPNFSNLDISKLLGKKWNEMSAEERTPFINEAKQLRIEHLNQYPEFRYXXXXXXXXXXXXXXIKTDLASPTNQ 726
            S HIK PMNAFMVW++I R+ +  Q P+  N +ISK LGK+W  +   ++ PFI EA++LR++H+  YP+++Y+PR++ K S      K  ++ P+++
Sbjct:   52 SGHIKRPMNAFMVWSQIERRKIMEQSPDMHNAEISKRLGKRWKLLKDGDKIPFIREAERLRLKHMADYPDYKYRPRKKVKSSGSKPSEKLSISKPSSK 149

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BLAST of SOXP-3 vs. Ensembl Xenopus
Match: cyp4f2 (cytochrome P450 family 4 subfamily F member 2 [Source:Xenbase;Acc:XB-GENE-6258041])

HSP 1 Score: 90.1225 bits (222), Expect = 1.329e-19
Identity = 35/73 (47.95%), Postives = 54/73 (73.97%), Query Frame = 1

Query:  433 SNHIKIPMNAFMVWAKINRKLMASQYPNFSNLDISKLLGKKWNEMSAEERTPFINEAKQLRIEHLNQYPEFRY 651
            S HIK PMNAFMVW++I R+ +  Q P+  N +ISK LGK+W ++   ++ PFI EA++LR++H+  YP+++Y
Sbjct:   57 SGHIKRPMNAFMVWSQIERRKIMEQSPDMHNAEISKRLGKRWKQLKDGDKIPFIREAERLRLKHMADYPDYKY 129

[Close]

BLAST of SOXP-3 vs. Ensembl Xenopus
Match: smad9 (SMAD family member 9 [Source:Xenbase;Acc:XB-GENE-484686])

HSP 1 Score: 90.1225 bits (222), Expect = 1.572e-19
Identity = 36/73 (49.32%), Postives = 54/73 (73.97%), Query Frame = 1

Query:  433 SNHIKIPMNAFMVWAKINRKLMASQYPNFSNLDISKLLGKKWNEMSAEERTPFINEAKQLRIEHLNQYPEFRY 651
            + HIK PMNAFMVW+KI R+ +  Q P+  N +ISK LGK+W  ++  E+ PFI EA++LR++H+  YP+++Y
Sbjct:   45 TGHIKRPMNAFMVWSKIERRKIMEQSPDMHNAEISKRLGKRWKMLNDSEKIPFIREAERLRLKHMADYPDYKY 117

[Close]

BLAST of SOXP-3 vs. Ensembl Xenopus
Match: sox7 (SRY-box 7 [Source:NCBI gene;Acc:549080])

HSP 1 Score: 88.9669 bits (219), Expect = 3.032e-19
Identity = 40/111 (36.04%), Postives = 65/111 (58.56%), Query Frame = 1

Query:  319 TENYLCRQFEDYPTIKDKIQVNREMKEFKDITKKSVKNSNHIKIPMNAFMVWAKINRKLMASQYPNFSNLDISKLLGKKWNEMSAEERTPFINEAKQLRIEHLNQYPEFRY 651
            TE   C   ++   + D +  +R  +E    T+        I+ PMNAFMVWAK  RK +A Q P+  N ++SK+LGK W  +S  ++ P++ EA++LR++H+  YP ++Y
Sbjct:   11 TEGLDCSPIDE--DLSDGLSPHRSPREKGSETR--------IRRPMNAFMVWAKDERKRLAVQNPDLHNAELSKMLGKSWKALSPAQKRPYVEEAERLRVQHMQDYPNYKY 111

[Close]

BLAST of SOXP-3 vs. Ensembl Xenopus
Match: SOX8 (SRY-box 8 [Source:NCBI gene;Acc:100497725])

HSP 1 Score: 89.7373 bits (221), Expect = 3.411e-19
Identity = 35/77 (45.45%), Postives = 54/77 (70.13%), Query Frame = 1

Query:  421 SVKNSNHIKIPMNAFMVWAKINRKLMASQYPNFSNLDISKLLGKKWNEMSAEERTPFINEAKQLRIEHLNQYPEFRY 651
             +K   H+K PMNAFMVWA+  R+ +A QYP+  N ++SK LGK W  +S  E+ PF+ EA++LR++H   +P+++Y
Sbjct:   98 GLKAKPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLSENEKRPFVEEAERLRVQHKKDHPDYKY 174

[Close]

BLAST of SOXP-3 vs. Ensembl Xenopus
Match: sox17b.3 (SRY-box 17 alpha [Source:NCBI gene;Acc:395066])

HSP 1 Score: 88.9669 bits (219), Expect = 3.659e-19
Identity = 39/92 (42.39%), Postives = 60/92 (65.22%), Query Frame = 1

Query:  400 FKDI-TKKSVKNSN-------HIKIPMNAFMVWAKINRKLMASQYPNFSNLDISKLLGKKWNEMSAEERTPFINEAKQLRIEHLNQYPEFRY 651
            F+D  TKK   ++N        I+ PMNAFMVWAK  RK +A Q P+  N ++SK+LGK W  ++   + PF+ EA++LR++H+  YP+++Y
Sbjct:   36 FQDAKTKKEAGSANSRGKAEARIRRPMNAFMVWAKDERKRLAQQNPDLHNAELSKMLGKSWKSLTLASKRPFVKEAERLRVQHIQDYPDYKY 127

[Close]

BLAST of SOXP-3 vs. Ensembl Mouse
Match: Sox8 (SRY (sex determining region Y)-box 8 [Source:MGI Symbol;Acc:MGI:98370])

HSP 1 Score: 90.5077 bits (223), Expect = 7.030e-21
Identity = 35/77 (45.45%), Postives = 55/77 (71.43%), Query Frame = 1

Query:  421 SVKNSNHIKIPMNAFMVWAKINRKLMASQYPNFSNLDISKLLGKKWNEMSAEERTPFINEAKQLRIEHLNQYPEFRY 651
            ++K   H+K PMNAFMVWA+  R+ +A QYP+  N ++SK LGK W  +S  E+ PF+ EA++LR++H   +P+++Y
Sbjct:   92 TLKAKPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLSESEKRPFVEEAERLRVQHKKDHPDYKY 168

[Close]

BLAST of SOXP-3 vs. Ensembl Mouse
Match: Sox17 (SRY (sex determining region Y)-box 17 [Source:MGI Symbol;Acc:MGI:107543])

HSP 1 Score: 87.8113 bits (216), Expect = 2.666e-20
Identity = 35/80 (43.75%), Postives = 54/80 (67.50%), Query Frame = 1

Query:  412 TKKSVKNSNHIKIPMNAFMVWAKINRKLMASQYPNFSNLDISKLLGKKWNEMSAEERTPFINEAKQLRIEHLNQYPEFRY 651
            T    K  + I+ PMNAFMVWAK  RK +A Q P+  N ++SK+LGK W  ++  E+ PF+ EA++LR++H+  +P ++Y
Sbjct:   58 TSGRAKAESRIRRPMNAFMVWAKDERKRLAQQNPDLHNAELSKMLGKSWKALTLAEKRPFVEEAERLRVQHMQDHPNYKY 137

[Close]

BLAST of SOXP-3 vs. Ensembl Mouse
Match: Sox17 (SRY (sex determining region Y)-box 17 [Source:MGI Symbol;Acc:MGI:107543])

HSP 1 Score: 87.8113 bits (216), Expect = 2.710e-20
Identity = 35/80 (43.75%), Postives = 54/80 (67.50%), Query Frame = 1

Query:  412 TKKSVKNSNHIKIPMNAFMVWAKINRKLMASQYPNFSNLDISKLLGKKWNEMSAEERTPFINEAKQLRIEHLNQYPEFRY 651
            T    K  + I+ PMNAFMVWAK  RK +A Q P+  N ++SK+LGK W  ++  E+ PF+ EA++LR++H+  +P ++Y
Sbjct:   58 TSGRAKAESRIRRPMNAFMVWAKDERKRLAQQNPDLHNAELSKMLGKSWKALTLAEKRPFVEEAERLRVQHMQDHPNYKY 137

[Close]

BLAST of SOXP-3 vs. Ensembl Mouse
Match: Sox11 (SRY (sex determining region Y)-box 11 [Source:MGI Symbol;Acc:MGI:98359])

HSP 1 Score: 91.2781 bits (225), Expect = 5.384e-20
Identity = 37/73 (50.68%), Postives = 53/73 (72.60%), Query Frame = 1

Query:  433 SNHIKIPMNAFMVWAKINRKLMASQYPNFSNLDISKLLGKKWNEMSAEERTPFINEAKQLRIEHLNQYPEFRY 651
            S HIK PMNAFMVW+KI R+ +  Q P+  N +ISK LGK+W  +   E+ PFI EA++LR++H+  YP+++Y
Sbjct:   46 SGHIKRPMNAFMVWSKIERRKIMEQSPDMHNAEISKRLGKRWKMLKDSEKIPFIREAERLRLKHMADYPDYKY 118

[Close]

BLAST of SOXP-3 vs. Ensembl Mouse
Match: Sox8 (SRY (sex determining region Y)-box 8 [Source:MGI Symbol;Acc:MGI:98370])

HSP 1 Score: 91.2781 bits (225), Expect = 8.213e-20
Identity = 35/84 (41.67%), Postives = 56/84 (66.67%), Query Frame = 1

Query:  400 FKDITKKSVKNSNHIKIPMNAFMVWAKINRKLMASQYPNFSNLDISKLLGKKWNEMSAEERTPFINEAKQLRIEHLNQYPEFRY 651
             +     ++K   H+K PMNAFMVWA+  R+ +A QYP+  N ++SK LGK W  +S  E+ PF+ EA++LR++H   +P+++Y
Sbjct:   85 VRGGGGGTLKAKPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLSESEKRPFVEEAERLRVQHKKDHPDYKY 168

[Close]

BLAST of SOXP-3 vs. UniProt/SwissProt
Match: sp|Q6IZ48|SOX8_TETNG (Transcription factor Sox-8 OS=Tetraodon nigroviridis OX=99883 GN=sox8 PE=2 SV=2)

HSP 1 Score: 95.5153 bits (236), Expect = 1.786e-20
Identity = 38/77 (49.35%), Postives = 57/77 (74.03%), Query Frame = 1

Query:  421 SVKNSNHIKIPMNAFMVWAKINRKLMASQYPNFSNLDISKLLGKKWNEMSAEERTPFINEAKQLRIEHLNQYPEFRY 651
            S+KN  H+K PMNAFMVWA+  R+ +A QYP+  N ++SK LGK W  +S  E+ PF++EA++LRI+H   +P+++Y
Sbjct:   93 SLKNKPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLSESEKRPFVDEAERLRIQHKKDHPDYKY 169

[Close]

BLAST of SOXP-3 vs. UniProt/SwissProt
Match: sp|P40657|SOX15_DROME (Putative transcription factor SOX-15 OS=Drosophila melanogaster OX=7227 GN=Sox15 PE=2 SV=2)

HSP 1 Score: 93.9745 bits (232), Expect = 1.222e-19
Identity = 38/78 (48.72%), Postives = 58/78 (74.36%), Query Frame = 1

Query:  418 KSVKNSNHIKIPMNAFMVWAKINRKLMASQYPNFSNLDISKLLGKKWNEMSAEERTPFINEAKQLRIEHLNQYPEFRY 651
            KS K S  I+ PMNAFMVWAKI RK +A + P+  N D+SK+LGKKW  ++ ++R P++ EA++LR+ H+ ++P ++Y
Sbjct:  208 KSAKESR-IRRPMNAFMVWAKIERKKLADENPDLHNADLSKMLGKKWRSLTPQDRRPYVEEAERLRVIHMTEHPNYKY 284

[Close]

BLAST of SOXP-3 vs. UniProt/SwissProt
Match: sp|P0C1G9|SOX11_RAT (Transcription factor SOX-11 OS=Rattus norvegicus OX=10116 GN=Sox11 PE=2 SV=1)

HSP 1 Score: 91.2781 bits (225), Expect = 3.766e-19
Identity = 37/73 (50.68%), Postives = 53/73 (72.60%), Query Frame = 1

Query:  433 SNHIKIPMNAFMVWAKINRKLMASQYPNFSNLDISKLLGKKWNEMSAEERTPFINEAKQLRIEHLNQYPEFRY 651
            S HIK PMNAFMVW+KI R+ +  Q P+  N +ISK LGK+W  +   E+ PFI EA++LR++H+  YP+++Y
Sbjct:   46 SGHIKRPMNAFMVWSKIERRKIMEQSPDMHNAEISKRLGKRWKMLKDSEKIPFIREAERLRLKHMADYPDYKY 118

[Close]

BLAST of SOXP-3 vs. UniProt/SwissProt
Match: sp|Q7M6Y2|SOX11_MOUSE (Transcription factor SOX-11 OS=Mus musculus OX=10090 GN=Sox11 PE=1 SV=1)

HSP 1 Score: 91.2781 bits (225), Expect = 3.766e-19
Identity = 37/73 (50.68%), Postives = 53/73 (72.60%), Query Frame = 1

Query:  433 SNHIKIPMNAFMVWAKINRKLMASQYPNFSNLDISKLLGKKWNEMSAEERTPFINEAKQLRIEHLNQYPEFRY 651
            S HIK PMNAFMVW+KI R+ +  Q P+  N +ISK LGK+W  +   E+ PFI EA++LR++H+  YP+++Y
Sbjct:   46 SGHIKRPMNAFMVWSKIERRKIMEQSPDMHNAEISKRLGKRWKMLKDSEKIPFIREAERLRLKHMADYPDYKY 118

[Close]

BLAST of SOXP-3 vs. UniProt/SwissProt
Match: sp|P35716|SOX11_HUMAN (Transcription factor SOX-11 OS=Homo sapiens OX=9606 GN=SOX11 PE=1 SV=2)

HSP 1 Score: 91.2781 bits (225), Expect = 4.363e-19
Identity = 37/73 (50.68%), Postives = 53/73 (72.60%), Query Frame = 1

Query:  433 SNHIKIPMNAFMVWAKINRKLMASQYPNFSNLDISKLLGKKWNEMSAEERTPFINEAKQLRIEHLNQYPEFRY 651
            S HIK PMNAFMVW+KI R+ +  Q P+  N +ISK LGK+W  +   E+ PFI EA++LR++H+  YP+++Y
Sbjct:   46 SGHIKRPMNAFMVWSKIERRKIMEQSPDMHNAEISKRLGKRWKMLKDSEKIPFIREAERLRLKHMADYPDYKY 118

[Close]

BLAST of SOXP-3 vs. TrEMBL
Match: H9CXV0 (SOXP-3 (Fragment) OS=Schmidtea mediterranea OX=79327 PE=2 SV=1)

HSP 1 Score: 480.33 bits (1235), Expect = 4.629e-169
Identity = 251/254 (98.82%), Postives = 251/254 (98.82%), Query Frame = 1

Query:  265 NLLSMFLNTPVTMNYCENTENYLCRQFEDYPTIKDKIQVNREMKEFKDITKKSVKNSNHIKIPMNAFMVWAKINRKLMASQYPNFSNLDISKLLGKKWNEMSAEERTPFINEAKQLRIEHLNQYPEFRYXXXXXXXXXXXXXXIKTDLASPTNQCSADFHSFENLNLPKISNFNFTDMNNFEVKNIYDYQPASINYNSEINLFNDYFDHTIDSGFQPIDSNLPSVSSLIYNSHPYTFNYNCEKSLAQFNYLEHE 1026
            NLLSMFLNTPVTMNYCENTENYLCRQFEDYPTIKDKIQVNREMKEFKDITKKSVKNSNHIKIP NAFMVWAKINRKLMASQYPNFSNLDISKLLGKKWNEMSAEERTPFINEAKQLRIEHLNQYPEFRYQ RRRQKKSKKSKPIKTDLASPTNQCSADFHSFENLNLPKISNFNFTDMNNFEVKNIYDYQPASINYNSEINLFNDYFDHTIDSGFQPIDSNLPSVSSLIYNSHPYTFNYNCEKSLA FNYLEHE
Sbjct:    1 NLLSMFLNTPVTMNYCENTENYLCRQFEDYPTIKDKIQVNREMKEFKDITKKSVKNSNHIKIPKNAFMVWAKINRKLMASQYPNFSNLDISKLLGKKWNEMSAEERTPFINEAKQLRIEHLNQYPEFRYQSRRRQKKSKKSKPIKTDLASPTNQCSADFHSFENLNLPKISNFNFTDMNNFEVKNIYDYQPASINYNSEINLFNDYFDHTIDSGFQPIDSNLPSVSSLIYNSHPYTFNYNCEKSLAPFNYLEHE 254

[Close]

BLAST of SOXP-3 vs. TrEMBL
Match: E9GZE6 (HMG box domain-containing protein (Fragment) OS=Daphnia pulex OX=6669 GN=DAPPUDRAFT_199562 PE=4 SV=1)

HSP 1 Score: 97.8265 bits (242), Expect = 1.254e-20
Identity = 47/107 (43.93%), Postives = 73/107 (68.22%), Query Frame = 1

Query:  400 FKDITKKSVKNSNHIKIPMNAFMVWAKINRKLMASQYPNFSNLDISKLLGKKWNEMSAEERTPFINEAKQLRIEHLNQYPEFRYXXXXXXXXXXXXXXIKTDLASPT 720
            + D T+   KN+  IK PMNAFMVW++I R+ +    P   N +ISK LGK+W  +S+EERTPFI EA++LR+ H+ +YP+++Y+PR++ + +K S   +    +PT
Sbjct:   39 YSDATQTKKKNTVRIKRPMNAFMVWSQIERRKICEIQPEMHNAEISKQLGKQWKTLSSEERTPFIQEAQRLRLLHIQEYPDYKYRPRKKTEVAKGSSAARKSCTTPT 145

[Close]

BLAST of SOXP-3 vs. TrEMBL
Match: A0A1B6CI02 (HMG box domain-containing protein (Fragment) OS=Clastoptera arizonana OX=38151 GN=g.19427 PE=4 SV=1)

HSP 1 Score: 99.3673 bits (246), Expect = 3.608e-20
Identity = 42/84 (50.00%), Postives = 60/84 (71.43%), Query Frame = 1

Query:  400 FKDITKKSVKNSNHIKIPMNAFMVWAKINRKLMASQYPNFSNLDISKLLGKKWNEMSAEERTPFINEAKQLRIEHLNQYPEFRY 651
            + D T+    N NHIK PMNAFMVW++I R+ +  Q P+  N +ISK LGK+W  ++ EER PFI EA++LR+ HL +YP+++Y
Sbjct:   34 YSDATQTKKNNPNHIKRPMNAFMVWSQIERRKICEQQPDMHNAEISKRLGKQWKLLTEEERQPFIEEAERLRLMHLQEYPDYKY 117

[Close]

BLAST of SOXP-3 vs. TrEMBL
Match: A0A482XS96 (HMG box domain-containing protein OS=Laodelphax striatellus OX=195883 GN=LSTR_LSTR007547 PE=4 SV=1)

HSP 1 Score: 100.908 bits (250), Expect = 4.141e-20
Identity = 41/84 (48.81%), Postives = 60/84 (71.43%), Query Frame = 1

Query:  400 FKDITKKSVKNSNHIKIPMNAFMVWAKINRKLMASQYPNFSNLDISKLLGKKWNEMSAEERTPFINEAKQLRIEHLNQYPEFRY 651
            + D T+    N NHIK PMNAFMVW++I R+ +  Q P+  N +ISK LG++W  ++ EER PFI EA++LR+ HL +YP+++Y
Sbjct:   31 YSDATQTKKNNPNHIKRPMNAFMVWSQIERRKICEQQPDMHNAEISKRLGRRWKTLTEEERQPFIEEAERLRLMHLQEYPDYKY 114

[Close]

BLAST of SOXP-3 vs. TrEMBL
Match: A0A1B6HFM9 (HMG box domain-containing protein (Fragment) OS=Homalodisca liturata OX=320908 GN=g.29342 PE=4 SV=1)

HSP 1 Score: 98.2117 bits (243), Expect = 5.668e-20
Identity = 41/84 (48.81%), Postives = 59/84 (70.24%), Query Frame = 1

Query:  400 FKDITKKSVKNSNHIKIPMNAFMVWAKINRKLMASQYPNFSNLDISKLLGKKWNEMSAEERTPFINEAKQLRIEHLNQYPEFRY 651
            + D T+    N NHIK PMNAFMVW++I R+ +    P+  N +ISK LG++W  +S EER PFI EA++LR+ HL +YP+++Y
Sbjct:   37 YSDATQTKKNNPNHIKRPMNAFMVWSQIERRKICELQPDMHNAEISKRLGRRWKTLSEEERQPFIEEAERLRLMHLQEYPDYKY 120

[Close]

BLAST of SOXP-3 vs. Ensembl Cavefish
Match: sox8b (SRY-box transcription factor 8 [Source:NCBI gene;Acc:103030792])

HSP 1 Score: 93.5893 bits (231), Expect = 9.820e-21
Identity = 37/77 (48.05%), Postives = 56/77 (72.73%), Query Frame = 1

Query:  421 SVKNSNHIKIPMNAFMVWAKINRKLMASQYPNFSNLDISKLLGKKWNEMSAEERTPFINEAKQLRIEHLNQYPEFRY 651
            S+KN  H+K PMNAFMVWA+  R+ +A QYP+  N ++SK LGK W  +S  E+ PF+ EA++LR++H   +P+++Y
Sbjct:   83 SLKNKPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLSENEKRPFVEEAERLRVQHKKDHPDYKY 159

[Close]

BLAST of SOXP-3 vs. Ensembl Cavefish
Match: sox8b (SRY-box transcription factor 8 [Source:NCBI gene;Acc:103030792])

HSP 1 Score: 93.5893 bits (231), Expect = 1.012e-20
Identity = 37/77 (48.05%), Postives = 56/77 (72.73%), Query Frame = 1

Query:  421 SVKNSNHIKIPMNAFMVWAKINRKLMASQYPNFSNLDISKLLGKKWNEMSAEERTPFINEAKQLRIEHLNQYPEFRY 651
            S+KN  H+K PMNAFMVWA+  R+ +A QYP+  N ++SK LGK W  +S  E+ PF+ EA++LR++H   +P+++Y
Sbjct:   83 SLKNKPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLSENEKRPFVEEAERLRVQHKKDHPDYKY 159

[Close]

BLAST of SOXP-3 vs. Ensembl Cavefish
Match: sox9b (transcription factor Sox-9 [Source:NCBI gene;Acc:103039568])

HSP 1 Score: 91.2781 bits (225), Expect = 7.089e-20
Identity = 36/77 (46.75%), Postives = 55/77 (71.43%), Query Frame = 1

Query:  421 SVKNSNHIKIPMNAFMVWAKINRKLMASQYPNFSNLDISKLLGKKWNEMSAEERTPFINEAKQLRIEHLNQYPEFRY 651
            S KN  H+K PMNAFMVWA+  R+ +A QYP+  N ++SK LGK W  ++  E+ PF+ EA++LR++H   +P+++Y
Sbjct:   94 SSKNKPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLNEGEKRPFVEEAERLRVQHKKDHPDYKY 170

[Close]

BLAST of SOXP-3 vs. Ensembl Cavefish
Match: sox9a (transcription factor Sox-9-A-like [Source:NCBI gene;Acc:103045523])

HSP 1 Score: 90.8929 bits (224), Expect = 7.833e-20
Identity = 36/77 (46.75%), Postives = 55/77 (71.43%), Query Frame = 1

Query:  421 SVKNSNHIKIPMNAFMVWAKINRKLMASQYPNFSNLDISKLLGKKWNEMSAEERTPFINEAKQLRIEHLNQYPEFRY 651
            S KN  H+K PMNAFMVWA+  R+ +A QYP+  N ++SK LGK W  ++  E+ PF+ EA++LR++H   +P+++Y
Sbjct:   93 SSKNKPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLNDAEKRPFVEEAERLRVQHKKDHPDYKY 169

[Close]

BLAST of SOXP-3 vs. Ensembl Cavefish
Match: sox9a (transcription factor Sox-9-A-like [Source:NCBI gene;Acc:103045523])

HSP 1 Score: 90.8929 bits (224), Expect = 8.561e-20
Identity = 36/77 (46.75%), Postives = 55/77 (71.43%), Query Frame = 1

Query:  421 SVKNSNHIKIPMNAFMVWAKINRKLMASQYPNFSNLDISKLLGKKWNEMSAEERTPFINEAKQLRIEHLNQYPEFRY 651
            S KN  H+K PMNAFMVWA+  R+ +A QYP+  N ++SK LGK W  ++  E+ PF+ EA++LR++H   +P+++Y
Sbjct:   93 SSKNKPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLNDAEKRPFVEEAERLRVQHKKDHPDYKY 169

[Close]

BLAST of SOXP-3 vs. Ensembl Sea Lamprey
Match: sox4b (SRY-box transcription factor 4b [Source:ZFIN;Acc:ZDB-GENE-040426-1274])

HSP 1 Score: 91.6633 bits (226), Expect = 4.932e-21
Identity = 35/73 (47.95%), Postives = 54/73 (73.97%), Query Frame = 1

Query:  433 SNHIKIPMNAFMVWAKINRKLMASQYPNFSNLDISKLLGKKWNEMSAEERTPFINEAKQLRIEHLNQYPEFRY 651
            S HIK PMNAFMVW++I R+ +  Q P+  N +ISK LG++W ++   E+ PFI EA++LR++H+  YP+++Y
Sbjct:   59 SGHIKRPMNAFMVWSQIERRKIMEQSPDMHNAEISKRLGRRWKQLKESEKVPFIREAERLRLKHMADYPDYKY 131

[Close]

BLAST of SOXP-3 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000010223.1 (pep scaffold:Pmarinus_7.0:GL478813:2555:9375:-1 gene:ENSPMAG00000009255.1 transcript:ENSPMAT00000010223.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 82.0333 bits (201), Expect = 7.665e-20
Identity = 32/67 (47.76%), Postives = 50/67 (74.63%), Query Frame = 1

Query:  451 PMNAFMVWAKINRKLMASQYPNFSNLDISKLLGKKWNEMSAEERTPFINEAKQLRIEHLNQYPEFRY 651
            PMNAFMVWAK  R+ +A Q P+  N ++SK+LGK W  ++ E R P + EA++LR+ HL+++P+++Y
Sbjct:    9 PMNAFMVWAKDERRRLAKQNPDLHNAELSKMLGKSWRALTPESRRPCVEEAERLRLLHLSEHPDYKY 75

[Close]

BLAST of SOXP-3 vs. Ensembl Sea Lamprey
Match: sox10 (SRY-box transcription factor 10 [Source:ZFIN;Acc:ZDB-GENE-011207-1])

HSP 1 Score: 84.7297 bits (208), Expect = 8.203e-19
Identity = 32/71 (45.07%), Postives = 51/71 (71.83%), Query Frame = 1

Query:  439 HIKIPMNAFMVWAKINRKLMASQYPNFSNLDISKLLGKKWNEMSAEERTPFINEAKQLRIEHLNQYPEFRY 651
            H+K PMNAFMVWA+  R+ ++ QYP   N ++SK LGK W  ++  E+ PF+ EA++LR++H   +P+++Y
Sbjct:  111 HVKRPMNAFMVWAQAARRKLSDQYPQLHNAELSKTLGKLWRLLNEGEKRPFVEEAERLRMQHKKDHPDYKY 181

[Close]

BLAST of SOXP-3 vs. Ensembl Sea Lamprey
Match: sox12 (SRY-box transcription factor 12 [Source:ZFIN;Acc:ZDB-GENE-040724-33])

HSP 1 Score: 85.1149 bits (209), Expect = 1.016e-18
Identity = 32/72 (44.44%), Postives = 53/72 (73.61%), Query Frame = 1

Query:  436 NHIKIPMNAFMVWAKINRKLMASQYPNFSNLDISKLLGKKWNEMSAEERTPFINEAKQLRIEHLNQYPEFRY 651
             HIK PMNAFMVW++I R+ +  + P+  N +ISK LG++W ++   E+ PF+ EA++LR++H+  YP+++Y
Sbjct:   58 GHIKRPMNAFMVWSQIERRKIMMESPDVHNAEISKRLGRRWKQLKDCEKVPFMREAERLRLKHMADYPDYKY 129

[Close]

BLAST of SOXP-3 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008165.1 (pep scaffold:Pmarinus_7.0:GL479973:18969:29522:-1 gene:ENSPMAG00000007384.1 transcript:ENSPMAT00000008165.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 78.9518 bits (193), Expect = 1.025e-17
Identity = 38/95 (40.00%), Postives = 55/95 (57.89%), Query Frame = 1

Query:  367 DKIQVNREMKEFKDITKKSVKNSNHIKIPMNAFMVWAKINRKLMASQYPNFSNLDISKLLGKKWNEMSAEERTPFINEAKQLRIEHLNQYPEFRY 651
            D   V  + K F+D   +      HIK PMNAFMVWAK  R+ +   +P+  N  ISK+LG +W  MS++E+ P+  E  +L   HL +YP ++Y
Sbjct:   37 DGGGVFGDAKVFRDGRGRHA-GEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSSISKILGSRWKAMSSQEKQPYYEEQARLSKLHLERYPGYKY 130

[Close]

BLAST of SOXP-3 vs. Ensembl Yeast
Match: NHP6B (High-mobility group (HMG) protein; binds to and remodels nucleosomes; involved in recruiting FACT and other chromatin remodelling complexes to the chromosomes; functionally redundant with Nhp6Ap; required for transcriptional initiation fidelity of some tRNA genes; homologous to mammalian HMGB1 and HMGB2; NHP6B has a paralog, NHP6A, that arose from the whole genome duplication [Source:SGD;Acc:S000002157])

HSP 1 Score: 46.9802 bits (110), Expect = 2.057e-7
Identity = 22/74 (29.73%), Postives = 47/74 (63.51%), Query Frame = 1

Query:  385 REMKEFKDITKKSVKNSNHIKIPMNAFMVWAKINRKLMASQYPNFSNLDISKLLGKKWNEMSAEERTPFINEAK 606
            ++ KE K  T +  K+ N  K  ++A+M +A  NR ++ S+ P+ +   + ++LG++W  ++AEE+ P+ ++A+
Sbjct:    8 KQPKEPKKRTTRRKKDPNAPKRGLSAYMFFANENRDIVRSENPDVTFGQVGRILGERWKALTAEEKQPYESKAQ 81

[Close]

BLAST of SOXP-3 vs. Ensembl Nematostella
Match: EDO39449 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S9V3])

HSP 1 Score: 90.1225 bits (222), Expect = 1.139e-22
Identity = 39/77 (50.65%), Postives = 55/77 (71.43%), Query Frame = 1

Query:  421 SVKNSNHIKIPMNAFMVWAKINRKLMASQYPNFSNLDISKLLGKKWNEMSAEERTPFINEAKQLRIEHLNQYPEFRY 651
            S  +  HIK PMNAFMVW++  R+ +A +YPN  N +ISKLLG +W+ +S EE+ PF+ EAK+LR  H  +YP++ Y
Sbjct:    2 SETDDQHIKRPMNAFMVWSRTERRKLALKYPNMLNCEISKLLGAEWSRLSEEEKRPFVTEAKRLRTIHNQKYPDYSY 78

[Close]

BLAST of SOXP-3 vs. Ensembl Nematostella
Match: EDO43746 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RXZ2])

HSP 1 Score: 85.5001 bits (210), Expect = 4.219e-21
Identity = 33/70 (47.14%), Postives = 53/70 (75.71%), Query Frame = 1

Query:  442 IKIPMNAFMVWAKINRKLMASQYPNFSNLDISKLLGKKWNEMSAEERTPFINEAKQLRIEHLNQYPEFRY 651
            +K PMN+FM+WAK+ R+  A + P   N +ISKLLGK WNE++ +++ PF+ +A++LRI H+ ++P +RY
Sbjct:    1 VKRPMNSFMIWAKVMRRKFAEENPKLHNAEISKLLGKAWNELTTKDKRPFVEKAERLRIRHMKEHPNYRY 70

[Close]

BLAST of SOXP-3 vs. Ensembl Nematostella
Match: EDO32843 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7STW6])

HSP 1 Score: 85.1149 bits (209), Expect = 9.274e-21
Identity = 38/80 (47.50%), Postives = 58/80 (72.50%), Query Frame = 1

Query:  412 TKKSVKNSN--HIKIPMNAFMVWAKINRKLMASQYPNFSNLDISKLLGKKWNEMSAEERTPFINEAKQLRIEHLNQYPEF 645
            T +S K S+  H+K PMNAFMVW++I R+ MA ++P+  N +ISK LGK+W  +S  E+ PF+ E+++LRI H+  YP++
Sbjct:   11 THESKKKSDMQHVKRPMNAFMVWSQIERRKMAEEHPDMHNAEISKRLGKRWKLLSESEKRPFVEESERLRIRHMQAYPDY 90

[Close]

BLAST of SOXP-3 vs. Ensembl Nematostella
Match: EDO37974 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SEA1])

HSP 1 Score: 88.1965 bits (217), Expect = 1.535e-19
Identity = 35/71 (49.30%), Postives = 53/71 (74.65%), Query Frame = 1

Query:  439 HIKIPMNAFMVWAKINRKLMASQYPNFSNLDISKLLGKKWNEMSAEERTPFINEAKQLRIEHLNQYPEFRY 651
            H+K PMNAFMVWA+  R+ +A QYP+  N ++SK LGK W  ++  E+ PFI EA++LRI+H  ++P+++Y
Sbjct:   63 HVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWKLLNDSEKKPFIEEAERLRIKHKREHPDYKY 133

[Close]

BLAST of SOXP-3 vs. Ensembl Nematostella
Match: EDO32666 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SUF3])

HSP 1 Score: 83.9593 bits (206), Expect = 8.268e-19
Identity = 32/76 (42.11%), Postives = 55/76 (72.37%), Query Frame = 1

Query:  424 VKNSNHIKIPMNAFMVWAKINRKLMASQYPNFSNLDISKLLGKKWNEMSAEERTPFINEAKQLRIEHLNQYPEFRY 651
            VK   H+K PMNAFMVW++  R+ +A + P   N +ISK LG +W +++ +++ PF+ EAK+LR +H+ ++P+++Y
Sbjct:    4 VKPVEHVKRPMNAFMVWSREERRKIAQENPKMHNSEISKRLGSEWKQLADDDKKPFVEEAKKLRAQHMKEHPDYKY 79

[Close]

BLAST of SOXP-3 vs. Ensembl Medaka
Match: sox8 (SRY-box transcription factor 8 [Source:NCBI gene;Acc:100304451])

HSP 1 Score: 93.5893 bits (231), Expect = 8.467e-21
Identity = 36/77 (46.75%), Postives = 57/77 (74.03%), Query Frame = 1

Query:  421 SVKNSNHIKIPMNAFMVWAKINRKLMASQYPNFSNLDISKLLGKKWNEMSAEERTPFINEAKQLRIEHLNQYPEFRY 651
            S+K+  H+K PMNAFMVWA+  R+ +A QYP+  N ++SK LGK W  +S  E+ PF++EA++LR++H   +P+++Y
Sbjct:   93 SLKSKPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLSESEKRPFVDEAERLRVQHKKDHPDYKY 169

[Close]

BLAST of SOXP-3 vs. Ensembl Medaka
Match: sox4b (SRY-box transcription factor 4b [Source:ZFIN;Acc:ZDB-GENE-040426-1274])

HSP 1 Score: 88.5817 bits (218), Expect = 1.354e-19
Identity = 35/73 (47.95%), Postives = 53/73 (72.60%), Query Frame = 1

Query:  433 SNHIKIPMNAFMVWAKINRKLMASQYPNFSNLDISKLLGKKWNEMSAEERTPFINEAKQLRIEHLNQYPEFRY 651
            S HIK PMNAFMVW++I R+ +  Q P+  N +ISK LGK+W  +   ++ PFI EA++LR++H+  YP+++Y
Sbjct:   61 SGHIKRPMNAFMVWSQIERRKIMEQSPDMHNAEISKRLGKRWKLLRDSDKIPFIREAERLRLKHMADYPDYKY 133

[Close]

BLAST of SOXP-3 vs. Ensembl Medaka
Match: sox14 (SRY-box transcription factor 14 [Source:NCBI gene;Acc:100304454])

HSP 1 Score: 87.0409 bits (214), Expect = 1.466e-19
Identity = 35/75 (46.67%), Postives = 55/75 (73.33%), Query Frame = 1

Query:  427 KNSNHIKIPMNAFMVWAKINRKLMASQYPNFSNLDISKLLGKKWNEMSAEERTPFINEAKQLRIEHLNQYPEFRY 651
            K ++HIK PMNAFMVW++  R+ MA + P   N +ISK LG +W  +S  E+ P+I+EAK+LR +H+ ++P+++Y
Sbjct:    3 KPADHIKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSESEKRPYIDEAKRLRAQHMKEHPDYKY 77

[Close]

BLAST of SOXP-3 vs. Ensembl Medaka
Match: ENSORLT00000029054.1 (transcription factor Sox-14-like [Source:NCBI gene;Acc:111949029])

HSP 1 Score: 86.2705 bits (212), Expect = 2.595e-19
Identity = 36/76 (47.37%), Postives = 53/76 (69.74%), Query Frame = 1

Query:  424 VKNSNHIKIPMNAFMVWAKINRKLMASQYPNFSNLDISKLLGKKWNEMSAEERTPFINEAKQLRIEHLNQYPEFRY 651
             K   HIK PMNAFMVW++  R+ MA + P   N +ISK LG +W  +S  ++ PFI+EAK+LR +HL ++P+++Y
Sbjct:    2 AKPVEHIKRPMNAFMVWSRGQRRKMARENPKMHNSEISKRLGAEWKTLSDSDKRPFIDEAKRLRAQHLREHPDYKY 77

[Close]

BLAST of SOXP-3 vs. Ensembl Medaka
Match: sox9 (SRY-box transcription factor 9 [Source:NCBI gene;Acc:100125805])

HSP 1 Score: 88.5817 bits (218), Expect = 5.344e-19
Identity = 35/77 (45.45%), Postives = 55/77 (71.43%), Query Frame = 1

Query:  421 SVKNSNHIKIPMNAFMVWAKINRKLMASQYPNFSNLDISKLLGKKWNEMSAEERTPFINEAKQLRIEHLNQYPEFRY 651
            S K+  H+K PMNAFMVWA+  R+ +A QYP+  N ++SK LGK W  ++  E+ PF+ EA++LR++H   +P+++Y
Sbjct:   97 SSKSKPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLNEVEKRPFVEEAERLRVQHKKDHPDYKY 173

[Close]

BLAST of SOXP-3 vs. Planmine SMEST
Match: SMESG000051170.1 (SMESG000051170.1)

HSP 1 Score: 493.041 bits (1268), Expect = 3.997e-177
Identity = 257/258 (99.61%), Postives = 257/258 (99.61%), Query Frame = 1

Query:  253 VINHNLLSMFLNTPVTMNYCENTENYLCRQFEDYPTIKDKIQVNREMKEFKDITKKSVKNSNHIKIPMNAFMVWAKINRKLMASQYPNFSNLDISKLLGKKWNEMSAEERTPFINEAKQLRIEHLNQYPEFRYXXXXXXXXXXXXXXIKTDLASPTNQCSADFHSFENLNLPKISNFNFTDMNNFEVKNIYDYQPASINYNSEINLFNDYFDHTIDSGFQPIDSNLPSVSSLIYNSHPYTFNYNCEKSLAQFNYLEHE 1026
            VINHNLLSMFLNTPVTMNYCENTENYLCRQFEDYPTIKDKIQVNREMKEFKDITKKSVKNSNHIKIPMNAFMVWAKINRKLMASQYPNFSNLDISKLLGKKWNEMSAEERTPFINEAKQLRIEHLNQYPEFRYQPRRRQKKSKKSKPIKTDLASPTNQCSADFHSFENLNLPKISNFNFTDMNNFEVKNIYDYQPASINYNSEINLFNDYFDHTIDSGFQPIDSNLPSVSSLIYNSHPYTFNYNCEKSLA FNYLEHE
Sbjct:   29 VINHNLLSMFLNTPVTMNYCENTENYLCRQFEDYPTIKDKIQVNREMKEFKDITKKSVKNSNHIKIPMNAFMVWAKINRKLMASQYPNFSNLDISKLLGKKWNEMSAEERTPFINEAKQLRIEHLNQYPEFRYQPRRRQKKSKKSKPIKTDLASPTNQCSADFHSFENLNLPKISNFNFTDMNNFEVKNIYDYQPASINYNSEINLFNDYFDHTIDSGFQPIDSNLPSVSSLIYNSHPYTFNYNCEKSLAPFNYLEHE 286

[Close]

BLAST of SOXP-3 vs. Planmine SMEST
Match: SMESG000011244.1 (SMESG000011244.1)

HSP 1 Score: 95.5153 bits (236), Expect = 2.157e-21
Identity = 50/127 (39.37%), Postives = 73/127 (57.48%), Query Frame = 1

Query:  283 LNTPVTMNYCENTENYLCRQFEDYPTIKDKIQ----VNREMKEFKDITKKSVKNSNHIKIPMNAFMVWAKINRKLMASQYPNFSNLDISKLLGKKWNEMSAEERTPFINEAKQLRIEHLNQYPEFRY 651
            L TP + +   N  +Y    F+D    KD+ Q     N +  +  +IT  S K  + +K PMNAFMVW++  R+ MA   P   N +ISK LG  W  +S E++ PFI+EAK+LR  H+ QYP+++Y
Sbjct:  205 LRTPKSEDIDRNQNDY----FDDCEFSKDQTQNVTTANSQTSQ-SNITSSSQKKDDRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKY 326

[Close]

BLAST of SOXP-3 vs. Planmine SMEST
Match: SMESG000011244.1 (SMESG000011244.1)

HSP 1 Score: 95.5153 bits (236), Expect = 2.212e-21
Identity = 50/127 (39.37%), Postives = 73/127 (57.48%), Query Frame = 1

Query:  283 LNTPVTMNYCENTENYLCRQFEDYPTIKDKIQ----VNREMKEFKDITKKSVKNSNHIKIPMNAFMVWAKINRKLMASQYPNFSNLDISKLLGKKWNEMSAEERTPFINEAKQLRIEHLNQYPEFRY 651
            L TP + +   N  +Y    F+D    KD+ Q     N +  +  +IT  S K  + +K PMNAFMVW++  R+ MA   P   N +ISK LG  W  +S E++ PFI+EAK+LR  H+ QYP+++Y
Sbjct:  204 LRTPKSEDIDRNQNDY----FDDCEFSKDQTQNVTTANSQTSQ-SNITSSSQKKDDRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKY 325

[Close]

BLAST of SOXP-3 vs. Planmine SMEST
Match: SMESG000050484.1 (SMESG000050484.1)

HSP 1 Score: 83.1889 bits (204), Expect = 3.813e-17
Identity = 43/112 (38.39%), Postives = 66/112 (58.93%), Query Frame = 1

Query:  325 NYLCRQFEDYPTIKDKIQVNREMKEFKDITKK---SVKNSNHIKIPMNAFMVWAKINRKLMASQYPNFSNLDISKLLGKKWNEMSAEERTPFINEAKQLRIEHLNQYPEFRY 651
            N  C + +D      KI   R ++  ++  K    S  +S+HIK PMNAFMVWA+  R+ +    P+  N +ISKLLG+KW  M+A ++ P+  E  +L  +H+ Q+PE+RY
Sbjct:  500 NVKCAETDDSQNSNGKILGARIVRSQRNPDKSDNMSRSSSSHIKRPMNAFMVWAREERRKILKACPDMHNSNISKLLGQKWKSMTAADKQPYYEEQSRLSRQHMEQHPEYRY 611

[Close]

BLAST of SOXP-3 vs. Planmine SMEST
Match: SMESG000067682.1 (SMESG000067682.1)

HSP 1 Score: 82.4185 bits (202), Expect = 5.246e-17
Identity = 41/116 (35.34%), Postives = 67/116 (57.76%), Query Frame = 1

Query:  322 ENYLCRQFEDY-PTIKD-----KIQVNREMKEFKDITKKSVKNSNHIKIPMNAFMVWAKINRKLMASQYPNFSNLDISKLLGKKWNEMSAEERTPFINEAKQLRIEHLNQYPEFRY 651
            E+Y C    +  P IKD     K +    ++  ++  K++ K    I+ PMNAFMVW++  R+ M+ + P   N +ISK LG  W  +S  ++ PFI+EAK+LR  H  ++P+++Y
Sbjct:  177 ESYHCDDMNNSSPEIKDNQSRLKTETQNSIQINQNANKQTDKKEARIRRPMNAFMVWSRGQRRKMSVENPKMHNSEISKRLGSMWKSLSEIDKKPFIDEAKRLRANHQKEHPDYKY 292

The following BLAST results are available for this feature:

BLAST of SOXP-3 vs. Ensembl Human
BLAST of SOXP-3 vs. Ensembl Celegans
BLAST of SOXP-3 vs. Ensembl Fly
BLAST of SOXP-3 vs. Ensembl Zebrafish
BLAST of SOXP-3 vs. Ensembl Xenopus
BLAST of SOXP-3 vs. Ensembl Mouse
BLAST of SOXP-3 vs. UniProt/SwissProt
BLAST of SOXP-3 vs. TrEMBL
BLAST of SOXP-3 vs. Ensembl Cavefish
BLAST of SOXP-3 vs. Ensembl Sea Lamprey
BLAST of SOXP-3 vs. Ensembl Yeast
BLAST of SOXP-3 vs. Ensembl Nematostella
BLAST of SOXP-3 vs. Ensembl Medaka
BLAST of SOXP-3 vs. Planmine SMEST

BLAST of SOXP-3 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
SOX11	9.085e-20	50.68	SRY-box transcription factor 11 [Source:HGNC Symbo...	[more]
SOX8	1.216e-19	45.45	SRY-box transcription factor 8 [Source:HGNC Symbol...	[more]
SOX9	1.463e-19	46.75	SRY-box transcription factor 9 [Source:HGNC Symbol...	[more]
SOX14	1.560e-19	48.00	SRY-box transcription factor 14 [Source:HGNC Symbo...	[more]
SOX18	1.635e-19	45.57	SRY-box transcription factor 18 [Source:HGNC Symbo...	[more]

BLAST of SOXP-3 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
sox-3	4.810e-20	44.21	SOX (Mammalian SRY box) family [Source:UniProtKB/...	[more]
sox-2	2.406e-19	46.84	Transcription factor sox-2 [Source:UniProtKB/Swis...	[more]
sox-2	2.406e-19	46.84	Transcription factor sox-2 [Source:UniProtKB/Swis...	[more]
sox-2	2.406e-19	46.84	Transcription factor sox-2 [Source:UniProtKB/Swis...	[more]
sem-2	4.706e-19	47.22	Transcription factor sem-2 [Source:UniProtKB/Swis...	[more]

BLAST of SOXP-3 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Sox15	1.219e-20	48.72	gene:FBgn0005613 transcript:FBtr0087576	[more]
Sox21b	8.628e-19	44.05	gene:FBgn0042630 transcript:FBtr0330116	[more]
Sox21b	9.248e-19	44.05	gene:FBgn0042630 transcript:FBtr0075747	[more]
Sox21b	9.248e-19	44.05	gene:FBgn0042630 transcript:FBtr0330115	[more]
SoxN	1.340e-18	44.87	gene:FBgn0029123 transcript:FBtr0079733	[more]

BLAST of SOXP-3 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
sox8a	4.061e-21	47.44	SRY-box transcription factor 8a [Source:ZFIN;Acc:Z...	[more]
sox9a	2.847e-20	46.75	SRY-box transcription factor 9a [Source:ZFIN;Acc:Z...	[more]
sox8b	9.348e-20	45.45	SRY-box transcription factor 8b [Source:ZFIN;Acc:Z...	[more]
sox12	1.735e-19	47.95	SRY-box transcription factor 12 [Source:ZFIN;Acc:Z...	[more]
sox4b	1.767e-19	41.84	SRY-box transcription factor 4b [Source:ZFIN;Acc:Z...	[more]

BLAST of SOXP-3 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
cyp4f2	1.329e-19	47.95	cytochrome P450 family 4 subfamily F member 2 [Sou...	[more]
smad9	1.572e-19	49.32	SMAD family member 9 [Source:Xenbase;Acc:XB-GENE-4...	[more]
sox7	3.032e-19	36.04	SRY-box 7 [Source:NCBI gene;Acc:549080]	[more]
SOX8	3.411e-19	45.45	SRY-box 8 [Source:NCBI gene;Acc:100497725]	[more]
sox17b.3	3.659e-19	42.39	SRY-box 17 alpha [Source:NCBI gene;Acc:395066]	[more]

BLAST of SOXP-3 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Sox8	7.030e-21	45.45	SRY (sex determining region Y)-box 8 [Source:MGI S...	[more]
Sox17	2.666e-20	43.75	SRY (sex determining region Y)-box 17 [Source:MGI ...	[more]
Sox17	2.710e-20	43.75	SRY (sex determining region Y)-box 17 [Source:MGI ...	[more]
Sox11	5.384e-20	50.68	SRY (sex determining region Y)-box 11 [Source:MGI ...	[more]
Sox8	8.213e-20	41.67	SRY (sex determining region Y)-box 8 [Source:MGI S...	[more]

BLAST of SOXP-3 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q6IZ48\|SOX8_TETNG	1.786e-20	49.35	Transcription factor Sox-8 OS=Tetraodon nigrovirid...	[more]
sp\|P40657\|SOX15_DROME	1.222e-19	48.72	Putative transcription factor SOX-15 OS=Drosophila...	[more]
sp\|P0C1G9\|SOX11_RAT	3.766e-19	50.68	Transcription factor SOX-11 OS=Rattus norvegicus O...	[more]
sp\|Q7M6Y2\|SOX11_MOUSE	3.766e-19	50.68	Transcription factor SOX-11 OS=Mus musculus OX=100...	[more]
sp\|P35716\|SOX11_HUMAN	4.363e-19	50.68	Transcription factor SOX-11 OS=Homo sapiens OX=960...	[more]

BLAST of SOXP-3 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
H9CXV0	4.629e-169	98.82	SOXP-3 (Fragment) OS=Schmidtea mediterranea OX=793...	[more]
E9GZE6	1.254e-20	43.93	HMG box domain-containing protein (Fragment) OS=Da...	[more]
A0A1B6CI02	3.608e-20	50.00	HMG box domain-containing protein (Fragment) OS=Cl...	[more]
A0A482XS96	4.141e-20	48.81	HMG box domain-containing protein OS=Laodelphax st...	[more]
A0A1B6HFM9	5.668e-20	48.81	HMG box domain-containing protein (Fragment) OS=Ho...	[more]

BLAST of SOXP-3 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
sox8b	9.820e-21	48.05	SRY-box transcription factor 8 [Source:NCBI gene;A...	[more]
sox8b	1.012e-20	48.05	SRY-box transcription factor 8 [Source:NCBI gene;A...	[more]
sox9b	7.089e-20	46.75	transcription factor Sox-9 [Source:NCBI gene;Acc:1...	[more]
sox9a	7.833e-20	46.75	transcription factor Sox-9-A-like [Source:NCBI gen...	[more]
sox9a	8.561e-20	46.75	transcription factor Sox-9-A-like [Source:NCBI gen...	[more]

BLAST of SOXP-3 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5


Match Name	E-value	Identity	Description
sox4b	4.932e-21	47.95	SRY-box transcription factor 4b [Source:ZFIN;Acc:Z...	[more]
ENSPMAT00000010223.1	7.665e-20	47.76	pep scaffold:Pmarinus_7.0:GL478813:2555:9375:-1 ge...	[more]
sox10	8.203e-19	45.07	SRY-box transcription factor 10 [Source:ZFIN;Acc:Z...	[more]
sox12	1.016e-18	44.44	SRY-box transcription factor 12 [Source:ZFIN;Acc:Z...	[more]
ENSPMAT00000008165.1	1.025e-17	40.00	pep scaffold:Pmarinus_7.0:GL479973:18969:29522:-1 ...	[more]

BLAST of SOXP-3 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 1


Match Name	E-value	Identity	Description
NHP6B	2.057e-7	29.73	High-mobility group (HMG) protein; binds to and re...	[more]

BLAST of SOXP-3 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5


Match Name	E-value	Identity	Description
EDO39449	1.139e-22	50.65	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO43746	4.219e-21	47.14	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO32843	9.274e-21	47.50	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO37974	1.535e-19	49.30	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO32666	8.268e-19	42.11	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of SOXP-3 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
sox8	8.467e-21	46.75	SRY-box transcription factor 8 [Source:NCBI gene;A...	[more]
sox4b	1.354e-19	47.95	SRY-box transcription factor 4b [Source:ZFIN;Acc:Z...	[more]
sox14	1.466e-19	46.67	SRY-box transcription factor 14 [Source:NCBI gene;...	[more]
ENSORLT00000029054.1	2.595e-19	47.37	transcription factor Sox-14-like [Source:NCBI gene...	[more]
sox9	5.344e-19	45.45	SRY-box transcription factor 9 [Source:NCBI gene;A...	[more]

BLAST of SOXP-3 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000051170.1	3.997e-177	99.61	SMESG000051170.1	[more]
SMESG000011244.1	2.157e-21	39.37	SMESG000011244.1	[more]
SMESG000011244.1	2.212e-21	39.37	SMESG000011244.1	[more]
SMESG000050484.1	3.813e-17	38.39	SMESG000050484.1	[more]
SMESG000067682.1	5.246e-17	35.34	SMESG000067682.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Cross References

External references for this transcript


Database	Accession
SmedGD GBrowse	SMED30008505
GenBank	AFD29621.1

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30008505 ID=SMED30008505|Name=SOXP-3|organism=Schmidtea mediterranea sexual|type=transcript|length=1052bp
CTTCGTGATATTAATTTACCTGCAAAATTCAGTTAAGGTTGGTTTTAGGC
AGCAAATTGTGCTACCATTCATGTTTTTCCATGCGACGCAAAAAGATACA
AAGAGAGTAGTAAAAATGCAGTTAAAAGAATGATTCATGCTTCTTGTTAA
AACATGAGTGATACATTTTACAGCCATGGATGAACATGAAGATAGCATGA
AATGTGTTTCGACTCGCATGACTTATTTTCTATTAAAACAAATTACTCTG
CAGTTATAAATCATAATTTGTTGAGCATGTTTCTAAATACTCCAGTAACC
ATGAATTATTGTGAAAACACCGAAAATTACCTGTGCAGACAATTCGAAGA
TTATCCAACTATCAAAGATAAAATTCAAGTAAATCGAGAAATGAAAGAAT
TCAAAGACATAACAAAGAAATCAGTGAAAAATTCCAACCACATTAAAATT
CCCATGAATGCTTTTATGGTTTGGGCAAAAATTAATCGAAAACTCATGGC
TAGCCAATATCCGAATTTCTCAAATTTAGATATCAGTAAATTGCTTGGGA
AAAAATGGAATGAAATGTCAGCTGAAGAACGGACTCCGTTTATTAATGAG
GCCAAGCAGCTTCGAATTGAGCATTTGAATCAGTATCCAGAATTTAGATA
TCAGCCCCGAAGACGACAAAAGAAATCAAAAAAATCAAAACCAATCAAAA
CCGATTTGGCTTCTCCGACCAATCAGTGTTCTGCAGATTTTCACAGTTTT
GAAAATTTAAATTTACCTAAAATATCAAATTTCAATTTTACCGATATGAA
TAATTTCGAGGTGAAAAATATCTACGATTATCAACCGGCCTCGATCAATT
ACAATTCCGAGATCAATTTATTTAATGATTATTTTGACCATACTATTGAT
TCGGGTTTCCAGCCAATCGACAGCAACCTCCCATCCGTCAGTTCCTTGAT
CTACAACAGTCATCCGTATACTTTCAATTATAACTGCGAAAAATCATTAG
CGCAATTTAATTACTTGGAACATGAATTGTTTTTGTAGTTTGATTTTTTC
TA

protein sequence of SMED30008505-orf-1

>SMED30008505-orf-1 ID=SMED30008505-orf-1|Name=SMED30008505-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=279bp
MCFDSHDLFSIKTNYSAVINHNLLSMFLNTPVTMNYCENTENYLCRQFED
YPTIKDKIQVNREMKEFKDITKKSVKNSNHIKIPMNAFMVWAKINRKLMA
SQYPNFSNLDISKLLGKKWNEMSAEERTPFINEAKQLRIEHLNQYPEFRY
QPRRRQKKSKKSKPIKTDLASPTNQCSADFHSFENLNLPKISNFNFTDMN
NFEVKNIYDYQPASINYNSEINLFNDYFDHTIDSGFQPIDSNLPSVSSLI
YNSHPYTFNYNCEKSLAQFNYLEHELFL*

Aliases

The feature 'SOXP-3' has the following synonyms


Synonym
sox9-1
soxP-3

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000014	zeta neoblast
PLANA:0000028	Category 2 cell
PLANA:0000035	Category 3 cell
PLANA:0000429	neoblast
PLANA:0002032	epidermal cell
PLANA:0002075	pigment cell
PLANA:0002109	X1 cell
PLANA:0002111	X2 cell
PLANA:0002142	parenchyma

Vocabulary: **INTERPRO**
Term	Definition
IPR036910	HMG_box_dom_sf
IPR009071	HMG_box_dom

Vocabulary: **molecular function**
Term	Definition
GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
GO:0003677	DNA binding

Vocabulary: **cellular component**
Term	Definition
GO:0005634	nucleus

Vocabulary: **biological process**
Term	Definition
GO:0006351	transcription, DNA-templated
GO:0006355	regulation of transcription, DNA-templated
GO:0006357	regulation of transcription from RNA polymerase II promoter

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR009071	High mobility group box domain	SMART	SM00398	hmgende2	coord: 80..150 e-value: 5.5E-21 score: 85.7
IPR009071	High mobility group box domain	PFAM	PF00505	HMG_box	coord: 82..149 e-value: 4.1E-19 score: 68.7
IPR009071	High mobility group box domain	PROSITE	PS50118	HMG_BOX_2	coord: 81..149 score: 17.973
IPR036910	High mobility group box domain superfamily	GENE3D	G3DSA:1.10.30.10		coord: 75..157 e-value: 6.1E-23 score: 82.9
IPR036910	High mobility group box domain superfamily	SUPERFAMILY	SSF47095	HMG-box	coord: 68..153
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 151..172
None	No IPR available	PANTHER	PTHR10270:SF161	SOX DOMAIN-CONTAINING PROTEIN DICHAETE-RELATED	coord: 48..173
None	No IPR available	PANTHER	PTHR10270	SOX TRANSCRIPTION FACTOR	coord: 48..173
None	No IPR available	CDD	cd01388	SOX-TCF_HMG-box	coord: 80..150 e-value: 6.31701E-27 score: 97.7541