LRRC50
|
Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30008476 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 10Note: Hover over icons to view figure legend
Homology
BLAST of LRRC50 vs. Ensembl Human
Match: DNAAF1 (dynein axonemal assembly factor 1 [Source:HGNC Symbol;Acc:HGNC:30539]) HSP 1 Score: 272.322 bits (695), Expect = 1.013e-84 Identity = 136/267 (50.94%), Postives = 183/267 (68.54%), Query Frame = 3
Query: 543 KWPRMTTDYLKKHCKENKLYITPRLNDILYLHYKGFAFIENLDEYVGLRCLFLETNGISKIENLEMLTELRCLYLSKNLISRIENIATLVNLDSIDLSHNLVAKIENLRNLPKFTKLILAHNKVQKISDLEELIYCDNISVLDLQHNQIDDPNVIEEIFAKMKSLRVLYLQGNQFMKNVKNYRKHVINLCKNLTYLDERPVFEKDRACAEAFCRGGIEEEKDERNRWVAKEQKRMDDSFEWLRQRRAKIEAQNHELKLKNEKESLGE 1343
+ PRMT L+K CK++KLYITP LND LYLH+KGF IENL+EY GLRCL+L++NGI KIENLE TELRCL+L NL+ +IEN+ L LD+++LS+N + IENL LP L +AHN ++ + D++ L C + VLDL HN++ DP ++ I M LRVL L GN ++ + NYR+ V K+LTYLD+RPVF KDRACAEA+ RGG EK+ER +W ++E+K++ DS E L A I+ + E K + E + GE
Sbjct: 84 RGPRMTKSSLQKLCKQHKLYITPALNDTLYLHFKGFDRIENLEEYTGLRCLWLQSNGIQKIENLEAQTELRCLFLQMNLLRKIENLEPLQKLDALNLSNNYIKTIENLSCLPVLNTLQMAHNHLETVEDIQHLQECLRLCVLDLSHNKLSDPEIL-SILESMPDLRVLNLMGNPVIRQIPNYRRTVTVRLKHLTYLDDRPVFPKDRACAEAWARGGYAAEKEERQQWESRERKKITDSIEAL----AMIKQRAEERKRQRESQERGE 345
BLAST of LRRC50 vs. Ensembl Human
Match: DNAAF1 (dynein axonemal assembly factor 1 [Source:HGNC Symbol;Acc:HGNC:30539]) HSP 1 Score: 276.174 bits (705), Expect = 7.836e-83 Identity = 136/267 (50.94%), Postives = 183/267 (68.54%), Query Frame = 3
Query: 543 KWPRMTTDYLKKHCKENKLYITPRLNDILYLHYKGFAFIENLDEYVGLRCLFLETNGISKIENLEMLTELRCLYLSKNLISRIENIATLVNLDSIDLSHNLVAKIENLRNLPKFTKLILAHNKVQKISDLEELIYCDNISVLDLQHNQIDDPNVIEEIFAKMKSLRVLYLQGNQFMKNVKNYRKHVINLCKNLTYLDERPVFEKDRACAEAFCRGGIEEEKDERNRWVAKEQKRMDDSFEWLRQRRAKIEAQNHELKLKNEKESLGE 1343
+ PRMT L+K CK++KLYITP LND LYLH+KGF IENL+EY GLRCL+L++NGI KIENLE TELRCL+L NL+ +IEN+ L LD+++LS+N + IENL LP L +AHN ++ + D++ L C + VLDL HN++ DP ++ I M LRVL L GN ++ + NYR+ V K+LTYLD+RPVF KDRACAEA+ RGG EK+ER +W ++E+K++ DS E L A I+ + E K + E + GE
Sbjct: 84 RGPRMTKSSLQKLCKQHKLYITPALNDTLYLHFKGFDRIENLEEYTGLRCLWLQSNGIQKIENLEAQTELRCLFLQMNLLRKIENLEPLQKLDALNLSNNYIKTIENLSCLPVLNTLQMAHNHLETVEDIQHLQECLRLCVLDLSHNKLSDPEIL-SILESMPDLRVLNLMGNPVIRQIPNYRRTVTVRLKHLTYLDDRPVFPKDRACAEAWARGGYAAEKEERQQWESRERKKITDSIEAL----AMIKQRAEERKRQRESQERGE 345
BLAST of LRRC50 vs. Ensembl Human
Match: DNAAF1 (dynein axonemal assembly factor 1 [Source:HGNC Symbol;Acc:HGNC:30539]) HSP 1 Score: 177.563 bits (449), Expect = 5.990e-51 Identity = 84/155 (54.19%), Postives = 113/155 (72.90%), Query Frame = 3
Query: 543 KWPRMTTDYLKKHCKENKLYITPRLNDILYLHYKGFAFIENLDEYVGLRCLFLETNGISKIENLEMLTELRCLYLSKNLISRIENIATLVNLDSIDLSHNLVAKIENLRNLPKFTKLILAHNKVQKISDLEELIYCDNISVLDLQHNQIDDPNVI 1007
+ PRMT L+K CK++KLYITP LND LYLH+KGF IENL+EY GLRCL+L++NGI KIENLE TELRCL+L NL+ +IEN+ L LD+++LS+N + IENL LP L +AHN ++ + D++ L C + VLDL HN++ DP ++
Sbjct: 84 RGPRMTKSSLQKLCKQHKLYITPALNDTLYLHFKGFDRIENLEEYTGLRCLWLQSNGIQKIENLEAQTELRCLFLQMNLLRKIENLEPLQKLDALNLSNNYIKTIENLSCLPVLNTLQMAHNHLETVEDIQHLQECLRLCVLDLSHNKLSDPEIL 238
BLAST of LRRC50 vs. Ensembl Human
Match: PPP1R7 (protein phosphatase 1 regulatory subunit 7 [Source:HGNC Symbol;Acc:HGNC:9295]) HSP 1 Score: 73.559 bits (179), Expect = 5.383e-14 Identity = 51/124 (41.13%), Postives = 71/124 (57.26%), Query Frame = 3
Query: 621 DILYLHYKGFAFIENLDEYVGLRCLFLETNGISKIENLEMLTELRCLYLSKNLISRIENIATLVNLDSIDLSHNLVAKIENLRNLPKFTKLILAHNKVQKISDLEELIYCDNISVLDLQHNQID 992
+IL + + IE +D+ L+ LFL N ISKIENL L +L+ L L N I IENI TL NL+S+ L N + K++NL L T L + N++ KI L+ L+ N+ L L HN I+
Sbjct: 102 EILDISFNLLRNIEGVDKLTRLKKLFLVNNKISKIENLSNLHQLQMLELGSNRIRAIENIDTLTNLESLFLGKNKITKLQNLDALTNLTVLSMQSNRLTKIEGLQNLV---NLRELYLSHNGIE 222 HSP 2 Score: 68.5514 bits (166), Expect = 2.650e-12 Identity = 57/154 (37.01%), Postives = 78/154 (50.65%), Query Frame = 3
Query: 657 IENLDEYVGLRCLFLETNGISKIENLEMLTELRCLYLSKNLISRIENIATLVNLDSIDLSHNLVAKIENLRNLPKFTKLILAHNKVQ-------------------KISDLEELIYCDNISVLDLQHNQIDDPNVIEEIFAKMKSLRVLYLQGN 1061
IENL+E LR L L N I KIENLE LTEL L +S NL+ IE + L L + L +N ++KIENL NL + L L N+++ KI+ L+ L N++VL +Q N++ E + +LR LYL N
Sbjct: 70 IENLEELQSLRELDLYDNQIKKIENLEALTELEILDISFNLLRNIEGVDKLTRLKKLFLVNNKISKIENLSNLHQLQMLELGSNRIRAIENIDTLTNLESLFLGKNKITKLQNLDALTNLTVLSMQSNRLTKI----EGLQNLVNLRELYLSHN 219 HSP 3 Score: 66.6254 bits (161), Expect = 1.282e-11 Identity = 40/103 (38.83%), Postives = 60/103 (58.25%), Query Frame = 3
Query: 627 LYLHYKGFAFIENLDEYVGLRCLFLETNGISKIENLEMLTELRCLYLSKNLISRIENIATLVNLDSIDLSHNLVAKIENLRNLPKFTKLILAHNKVQKISDLE 935
L+L + IENL L+ L L +N I IEN++ LT L L+L KN I++++N+ L NL + + N + KIE L+NL +L L+HN ++ I LE
Sbjct: 126 LFLVNNKISKIENLSNLHQLQMLELGSNRIRAIENIDTLTNLESLFLGKNKITKLQNLDALTNLTVLSMQSNRLTKIEGLQNLVNLRELYLSHNGIEVIEGLE 228 HSP 4 Score: 57.3806 bits (137), Expect = 1.644e-8 Identity = 32/72 (44.44%), Postives = 44/72 (61.11%), Query Frame = 3
Query: 657 IENLDEYVGLRCLFLETNGISKIENLEMLTELRCLYLSKNLISRIENIATLVNLDSIDLSHNLVAKIENLRN 872
IEN+D L LFL N I+K++NL+ LT L L + N +++IE + LVNL + LSHN + IE L N
Sbjct: 158 IENIDTLTNLESLFLGKNKITKLQNLDALTNLTVLSMQSNRLTKIEGLQNLVNLRELYLSHNGIEVIEGLEN 229
BLAST of LRRC50 vs. Ensembl Human
Match: PPP1R7 (protein phosphatase 1 regulatory subunit 7 [Source:HGNC Symbol;Acc:HGNC:9295]) HSP 1 Score: 73.559 bits (179), Expect = 7.543e-14 Identity = 51/124 (41.13%), Postives = 71/124 (57.26%), Query Frame = 3
Query: 621 DILYLHYKGFAFIENLDEYVGLRCLFLETNGISKIENLEMLTELRCLYLSKNLISRIENIATLVNLDSIDLSHNLVAKIENLRNLPKFTKLILAHNKVQKISDLEELIYCDNISVLDLQHNQID 992
+IL + + IE +D+ L+ LFL N ISKIENL L +L+ L L N I IENI TL NL+S+ L N + K++NL L T L + N++ KI L+ L+ N+ L L HN I+
Sbjct: 139 EILDISFNLLRNIEGVDKLTRLKKLFLVNNKISKIENLSNLHQLQMLELGSNRIRAIENIDTLTNLESLFLGKNKITKLQNLDALTNLTVLSMQSNRLTKIEGLQNLV---NLRELYLSHNGIE 259 HSP 2 Score: 68.5514 bits (166), Expect = 4.255e-12 Identity = 57/154 (37.01%), Postives = 78/154 (50.65%), Query Frame = 3
Query: 657 IENLDEYVGLRCLFLETNGISKIENLEMLTELRCLYLSKNLISRIENIATLVNLDSIDLSHNLVAKIENLRNLPKFTKLILAHNKVQ-------------------KISDLEELIYCDNISVLDLQHNQIDDPNVIEEIFAKMKSLRVLYLQGN 1061
IENL+E LR L L N I KIENLE LTEL L +S NL+ IE + L L + L +N ++KIENL NL + L L N+++ KI+ L+ L N++VL +Q N++ E + +LR LYL N
Sbjct: 107 IENLEELQSLRELDLYDNQIKKIENLEALTELEILDISFNLLRNIEGVDKLTRLKKLFLVNNKISKIENLSNLHQLQMLELGSNRIRAIENIDTLTNLESLFLGKNKITKLQNLDALTNLTVLSMQSNRLTKI----EGLQNLVNLRELYLSHN 256 HSP 3 Score: 66.6254 bits (161), Expect = 1.690e-11 Identity = 40/103 (38.83%), Postives = 60/103 (58.25%), Query Frame = 3
Query: 627 LYLHYKGFAFIENLDEYVGLRCLFLETNGISKIENLEMLTELRCLYLSKNLISRIENIATLVNLDSIDLSHNLVAKIENLRNLPKFTKLILAHNKVQKISDLE 935
L+L + IENL L+ L L +N I IEN++ LT L L+L KN I++++N+ L NL + + N + KIE L+NL +L L+HN ++ I LE
Sbjct: 163 LFLVNNKISKIENLSNLHQLQMLELGSNRIRAIENIDTLTNLESLFLGKNKITKLQNLDALTNLTVLSMQSNRLTKIEGLQNLVNLRELYLSHNGIEVIEGLE 265 HSP 4 Score: 57.3806 bits (137), Expect = 2.240e-8 Identity = 32/72 (44.44%), Postives = 44/72 (61.11%), Query Frame = 3
Query: 657 IENLDEYVGLRCLFLETNGISKIENLEMLTELRCLYLSKNLISRIENIATLVNLDSIDLSHNLVAKIENLRN 872
IEN+D L LFL N I+K++NL+ LT L L + N +++IE + LVNL + LSHN + IE L N
Sbjct: 195 IENIDTLTNLESLFLGKNKITKLQNLDALTNLTVLSMQSNRLTKIEGLQNLVNLRELYLSHNGIEVIEGLEN 266
BLAST of LRRC50 vs. Ensembl Celegans
Match: sds-22 (Protein phosphatase 1 regulatory subunit SDS22 homolog [Source:UniProtKB/Swiss-Prot;Acc:P45969]) HSP 1 Score: 81.2629 bits (199), Expect = 1.555e-16 Identity = 65/210 (30.95%), Postives = 101/210 (48.10%), Query Frame = 3
Query: 627 LYLHYKGFAFIENLDEYVGLRCLFLETNGISKIENLEMLTELRCLYLSKNLISRIENIATLVNLDSIDLSHNLVAKIENLRNLPKFTKLILAHNKVQKISDLEEL-----IYCD--------------NISVLDLQHNQIDDPNVIEEI---------------------FAKMKSLRVLYLQGNQFMKNVKN-YRKHVINLCKNLTYLD 1133
L L Y I LD+ L L+L +N I KIENLE LT+L+ L L N I +IENI LVNLD + + N + ++E + L K + L L N++ KI ++E+L +Y N+ +LD+ +N+I + +E + +K+K L+ +YL+ N F N N YR+ V+ +T +D
Sbjct: 108 LDLSYNRIRQINGLDKLTKLETLYLVSNKIEKIENLEALTQLKLLELGDNRIKKIENIGHLVNLDELFIGKNKIRQLEGVETLQKLSVLSLPGNRIVKIENVEQLNNLKELYLSDQGLQDIHGVEPLTNLLLLDVANNEIKTFSGVERLESLNDFWANDNKVESFSEIEQLSKLKGLQTVYLERNPFYFNDTNQYRRKVMMTLTQVTQID 317 HSP 2 Score: 62.7734 bits (151), Expect = 2.028e-10 Identity = 53/159 (33.33%), Postives = 84/159 (52.83%), Query Frame = 3
Query: 657 IENLDEYVGLRCLFLETNGISKIENLEMLTELRCLYLSKNLISRIENIATLVNLDSIDLSHNLVAKIENLRNLPKFTKLILAHNKVQKISDLEELIYCDNISVLDLQHNQIDDPNVIEEIFAKMKSLRVLYLQGNQFMKNVKNYRKHVINLCKNLTYLD 1133
I +L+ V L L L N I +I L+ LT+L LYL N I +IEN+ L L ++L N + KIEN+ +L +L + NK++++ +E L +SVL L N+I V E ++ +L+ LYL +Q ++++ H + NL LD
Sbjct: 96 ISHLESLVNLVSLDLSYNRIRQINGLDKLTKLETLYLVSNKIEKIENLEALTQLKLLELGDNRIKKIENIGHLVNLDELFIGKNKIRQLEGVETL---QKLSVLSLPGNRI----VKIENVEQLNNLKELYL-SDQGLQDI-----HGVEPLTNLLLLD 241 HSP 3 Score: 49.6766 bits (117), Expect = 3.107e-6 Identity = 48/153 (31.37%), Postives = 73/153 (47.71%), Query Frame = 3
Query: 711 GISKIENLEM--------------LTELRCLYLSKNLISRIENIATLVNLDSIDLSHNLVAKIENLRNLPKFTKLILAHNKVQKISDLEELIYCDNISVLDLQHNQIDD-PNV-----IEEIFAK------------MKSLRVLYLQGNQFMK 1073
G KIE L M L L L L +N ++ I ++ +LVNL S+DLS+N + +I L L K L L NK++KI +LE L + +L+L N+I N+ ++E+F ++ L VL L GN+ +K
Sbjct: 56 GFPKIEELRMRNNLLVSISPTISSLVTLTSLDLYENQLTEISHLESLVNLVSLDLSYNRIRQINGLDKLTKLETLYLVSNKIEKIENLEALT---QLKLLELGDNRIKKIENIGHLVNLDELFIGKNKIRQLEGVETLQKLSVLSLPGNRIVK 205
BLAST of LRRC50 vs. Ensembl Celegans
Match: C06A8.6 (pep chromosome:WBcel235:II:7772499:7773914:1 gene:WBGene00015516.1 transcript:C06A8.6.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:C06A8.6) HSP 1 Score: 77.0258 bits (188), Expect = 5.824e-15 Identity = 53/135 (39.26%), Postives = 81/135 (60.00%), Query Frame = 3
Query: 657 IENLDEYVGLRCLFLETNGISKIENLEMLTELRCLYLSKNLISRIENIATLVNLDSIDLSHNLVAKIENLRNLPKFTKLILAHNKVQKISDLEELIYCDNISVLDLQHNQIDDPNVIEEIFAKMKSLRVLYLQGN 1061
+ENLD V L L L N I+KIENLE LT+L+ L+ N I++IE + TL L+ ++L N +AKIENL N K +L L N+++ I +++ L ++VL L N I V++ I + + +L+ +YL N
Sbjct: 91 VENLDSLVNLESLDLSFNRITKIENLEKLTKLKTLFFVHNKITKIEGLDTLTELEYLELGDNRIAKIENLDNNLKLDRLFLGANQIRLIENVDHL---KKLTVLSLPANAI---TVVDNI-SGLHNLKEIYLAQN 218 HSP 2 Score: 70.4774 bits (171), Expect = 8.521e-13 Identity = 54/131 (41.22%), Postives = 75/131 (57.25%), Query Frame = 3
Query: 708 NGISKIENLEMLTELRCLYLSKNLISRIENIATLVNLDSIDLSHNLVAKIENLRNLPKFTKLILAHNKVQKISDLEELIYCDNISVLDLQHNQIDDPNVIEEIFAKMKSLRVLYLQGNQ--FMKNVKNYRK 1094
N I KIENL+ LT L L N I+++EN+ +LVNL+S+DLS N + KIENL L K L HNK+ KI L+ L + L+L N+I IE + +K R L+L NQ ++NV + +K
Sbjct: 64 NLIKKIENLDCLTTLTHLEFYDNQITKVENLDSLVNLESLDLSFNRITKIENLEKLTKLKTLFFVHNKITKIEGLDTLT---ELEYLELGDNRIAK---IENLDNNLKLDR-LFLGANQIRLIENVDHLKK 187 HSP 3 Score: 63.5438 bits (153), Expect = 1.310e-10 Identity = 60/212 (28.30%), Postives = 96/212 (45.28%), Query Frame = 3
Query: 627 LYLHYKGFAFIENLDEYVGLRCLFLETNGISKIENLEMLTELRCLYLSKNLISRIENIATLVNLDSIDLSHNLVAKIENLRNLPKFTKLILAHNK------VQKISDLEELIYCDN-------------ISVLDLQHNQIDDPNVIEEIFAKMKSLRVLYLQGNQF------------------------MKNVKNYRKHVINLCKNLTYLD 1133
L L + IENL++ L+ LF N I+KIE L+ LTEL L L N I++IEN+ + LD + L N + IEN+ +L K T L L N + + +L+E+ N + +LD N+++ +E I ++K+L + +GN+ + +V YR VI+L + +T LD
Sbjct: 103 LDLSFNRITKIENLEKLTKLKTLFFVHNKITKIEGLDTLTELEYLELGDNRIAKIENLDNNLKLDRLFLGANQIRLIENVDHLKKLTVLSLPANAITVVDNISGLHNLKEIYLAQNGIKYVCGIDEHLPLEILDFNQNRLEK---VENIH-QLKTLTDFWARGNKLDNWSIMDELVELPQLNSVYLDFNPIASVDTYRGKVIHLLQQITRLD 310 HSP 4 Score: 61.6178 bits (148), Expect = 5.023e-10 Identity = 55/149 (36.91%), Postives = 75/149 (50.34%), Query Frame = 3
Query: 636 HYKGFAF-------IENLDEYVGLRCLFLETNGISKIENLEMLTELRCLYLSKNLISRIENIATLVNLDSIDLSHNLVAKIENLRNLPKFTKLILAHNKVQKISDLEELIYCDNISVLDLQHNQIDDPNVIEEIFAKMKSLRVLYLQGN 1061
H + F+F IENLD L L N I+K+ENL+ L L L LS N I++IEN+ L L ++ HN + KIE L L + L L N++ KI +L+ + D L L NQI +IE + +K L VL L N
Sbjct: 55 HVEHFSFRWNLIKKIENLDCLTTLTHLEFYDNQITKVENLDSLVNLESLDLSFNRITKIENLEKLTKLKTLFFVHNKITKIEGLDTLTELEYLELGDNRIAKIENLDNNLKLDR---LFLGANQI---RLIENV-DHLKKLTVLSLPAN 196
BLAST of LRRC50 vs. Ensembl Celegans
Match: K10D2.8 (pep chromosome:WBcel235:III:5188726:5190175:1 gene:WBGene00189952.1 transcript:K10D2.8.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:K10D2.8) HSP 1 Score: 68.9366 bits (167), Expect = 2.033e-12 Identity = 52/164 (31.71%), Postives = 86/164 (52.44%), Query Frame = 3
Query: 657 IENLDEYVGLRCLFLETNGISKIENLEMLTELRCLYLSKNLISRIENIATLVNLDSIDLSHNLVAKIENLRNLPKFTKLILAHNKVQKISDLEELIYCDNISVLDLQHNQIDDPNVIEEIFAKMKSLRVLYLQGNQFMKNVKNYRKHVINLCKNLTYLDERPVF 1148
+ENL V L LFL N I KIE L+ + +L+ L L N + IE + TL L SI L+ N + KI+ L L L L N ++K+ ++E+ IS L ++ N+++ + ++ K+++L VL ++ N + YR V + ++ LD P+F
Sbjct: 152 MENLSHLVNLERLFLGANQIRKIEGLDGMAQLKELSLPGNALQIIEGLDTLSGLKSISLAQNGIRKIDGLSGLTNLKSLDLNDNIIEKLENVEQF---KGISSLMIRKNKLNCWQDVRQL-KKLENLTVLTMEMNPLYSSDYTYRNRVKEILPDVKLLDGFPIF 311 HSP 2 Score: 66.2402 bits (160), Expect = 1.546e-11 Identity = 45/155 (29.03%), Postives = 84/155 (54.19%), Query Frame = 3
Query: 627 LYLHYKGFAFIENLDEYVGLRCLFLETNGISKIENLEMLTELRCLYLSKNLISRIENIATLVNLDSIDLSHNLVAKIENLRNLPKFTKLILAHNKVQKISDLEELIYCDNISVLDLQHNQIDDP-----NVIEEIFAKMKSLR---VLYLQGNQF 1067
L+L IE LD L+ L L N + IE L+ L+ L+ + L++N I +I+ ++ L NL S+DL+ N++ K+EN+ + L++ NK+ D+ +L +N++VL ++ N + N ++EI +K L + ++QG+ +
Sbjct: 164 LFLGANQIRKIEGLDGMAQLKELSLPGNALQIIEGLDTLSGLKSISLAQNGIRKIDGLSGLTNLKSLDLNDNIIEKLENVEQFKGISSLMIRKNKLNCWQDVRQLKKLENLTVLTMEMNPLYSSDYTYRNRVKEILPDVKLLDGFPIFWVQGDPY 318 HSP 3 Score: 59.3066 bits (142), Expect = 2.991e-9 Identity = 37/85 (43.53%), Postives = 52/85 (61.18%), Query Frame = 3
Query: 681 GLRCLFLETNGISKIENLEMLTELRCLYLSKNLISRIENIATLVNLDSIDLSHNLVAKIENLRNLPKFTKLILAHNKVQKISDLE 935
G+R L L N + KI++ + LT L L L+ N I ++EN+ TLVNL +D+S+N + KIE L L +L L HNK+ I LE
Sbjct: 50 GIRDLSLRWNLLKKIDHFQCLTSLTRLNLNDNQIEKLENLETLVNLVFLDVSYNRITKIEGLSELINLEELHLVHNKIITIEGLE 134
BLAST of LRRC50 vs. Ensembl Celegans
Match: F13E9.1 (pep chromosome:WBcel235:IV:10864331:10873632:1 gene:WBGene00008750.1 transcript:F13E9.1.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:F13E9.1) HSP 1 Score: 53.1434 bits (126), Expect = 3.987e-7 Identity = 44/130 (33.85%), Postives = 74/130 (56.92%), Query Frame = 3
Query: 726 ENLEMLTELRCLYLSKNLISRI-ENIATLVNLDSIDLSHNLVAKIENL-RNLPKFTKLILAHNKVQKISDLEELIYCDNISVLDLQHNQIDDPNVIEEIFAKMKSLRVLYLQGNQFMKNVKNYRKHVINL 1109
E++++L E+R L +S N I+ I N+A L +L +DLS+N + KI+ L KLIL+ N ++ +S L +L ++ LD + N I + + ++ I K+ L +L L+ N K V+ YR V+ L
Sbjct: 306 ESMKLLPEVRVLNVSYNSITEIGSNLAFLSSLTELDLSNNTLTKIDGWNEKLGNIKKLILSENAIEDLSGLGKLY---SLEYLDAKGNNIQNLDAVQGI-GKLPCLEILLLRDNPIRKLVE-YRTKVLEL 430
BLAST of LRRC50 vs. Ensembl Fly
Match: dtr (gene:FBgn0023090 transcript:FBtr0081516) HSP 1 Score: 233.417 bits (594), Expect = 2.042e-65 Identity = 131/308 (42.53%), Postives = 195/308 (63.31%), Query Frame = 3
Query: 552 RMTTDYLKKHCKENKLYITPRLNDILYLHYKGFAFIENLDEYVGLRCLFLETNGISKIENLEMLTELRCLYLSKNLISRIENIATLVNLDSIDLSHNLVAKIENLRN--LPKFTKLILAHNKVQKISDLEELIYCDNISVLDLQHNQIDDPNVIEEIFAKMKSLRVLYLQGNQFMKNVKNYRKHVINLCKNLTYLDERPVFEKDRACAEAFCRGGIEEEKDERNRWVAKEQKRMDDSFEWLRQRRAKIEAQNHELKLKNEKESLGESIAD-----ICVKPGEVDWLY----GPQEVYDDLTTSNDAID 1442
RMT LK+ CK++KLY TPRLND+LYLHY+GF IE+L+EY L+CL+LE N IS+I+ LE L++L+CL+L NLI++IEN+ LD+++LS N + KI+N+ LP L ++ N ++ L +LI C +SVLDL +N+IDD +I +IF +M +L+VL LQGN + + YRK +I CK LTYLD RPVF +DRACAEA+ R G E E+ E NRW E+++ +S + R + + L +S ++ A+ + ++ G VD L+ G Q + +D T S+ +++
Sbjct: 14 RMTPKGLKELCKKDKLYQTPRLNDVLYLHYQGFQCIESLEEYTELKCLWLECNAISEIQGLEKLSKLKCLFLQNNLITKIENLDPCRELDTLNLSSNHIRKIQNIGTNVLPVLNTLTISSNYLKDSESLSDLIQCKTLSVLDLSNNRIDDI-LIVKIFEQMLNLKVLVLQGNPVVSRLPQYRKTLILACKELTYLDSRPVFPRDRACAEAWKRDGYEGERKENNRWNRAERRKTRESINCTIRMRNSHRPPDQQDPLLRSSDSEDDTCAETARKKVALENGCVDDLWEEVSGEQPISEDGTNSSSSLE 320
BLAST of LRRC50 vs. Ensembl Fly
Match: sds22 (gene:FBgn0028992 transcript:FBtr0083436) HSP 1 Score: 82.8037 bits (203), Expect = 5.726e-17 Identity = 65/181 (35.91%), Postives = 92/181 (50.83%), Query Frame = 3
Query: 657 IENLDEYVGLRCLFLETNGISKIENLEMLTELRCLYLSKNLISRIENIATLVNLDSIDLSHNLVAKIENLRNLPKFTKLILAHNKVQKISDLEELIYCDNISVLDLQ----------------------HNQIDDPNVIEEIFAKMKSLRVLYLQGNQFMKNVKNYRKHVINLCKNLTYLD 1133
IENLD L L L N + KIEN+EML LR L+L KN I++IEN+ TLVNL+ + L N + KIENL L +L ++ N V+ I +L E + LDL HN +DD I E+ K+L+ +YL+ N K+V+ YR + ++ L +D
Sbjct: 142 IENLDMLTNLTMLELGDNKLKKIENIEMLVNLRQLFLGKNKIAKIENLDTLVNLEILSLQANRIVKIENLEKLANLRELYVSENGVETIENLSE---NTKLETLDLAKNRLKGIANLEKLELLEELWLNHNGVDDWKDI-ELLKVNKALQTIYLEYNPLAKDVR-YRSKLRDILPQLQKID 317 HSP 2 Score: 65.0846 bits (157), Expect = 4.920e-11 Identity = 52/149 (34.90%), Postives = 82/149 (55.03%), Query Frame = 3
Query: 627 LYLHYKGFAFIENLDEYVGLRCLFLETNGISKIENLEMLTELRCLYLSKNLISRIENIATLVNLDSIDLSHNLVAKIENLRNLPKFTKLILAHNKVQKISDLEELIYCDNISVLDLQHNQIDDPNVIEEIFAKMKSLRVLYLQGNQFMK 1073
L L+++ +EN + + LFL N I KIENL L L L L N I++IEN+ L +L+ +D+S N + KIENL L K K+ N++ +I +L+ L N+++L+L N++ IE + +LR L+L N+ K
Sbjct: 44 LDLNHRRIEKLENFEPLTRIERLFLRWNLIKKIENLSSLKTLIELELYDNQITKIENLDDLPHLEVLDISFNRLTKIENLDKLVKLEKVYFVSNRITQIENLDML---TNLTMLELGDNKLKKIENIEMLV----NLRQLFLGKNKIAK 185
BLAST of LRRC50 vs. Ensembl Fly
Match: TbCMF46 (gene:FBgn0032163 transcript:FBtr0079898) HSP 1 Score: 67.3958 bits (163), Expect = 1.732e-11 Identity = 45/121 (37.19%), Postives = 67/121 (55.37%), Query Frame = 3
Query: 627 LYLHYKGFAFIENLDEYVGLRCLFLETNGISKIENLEMLTELRCLYLSKNLISRIENIATLVNLDSIDLSHNLVAKIENLRNLPKFTKLILAHNKVQKISDLEELIYCDNISVLDLQHNQI 989
+ L +K I++L L L L N I IE+LEMLT L+ L LS N I+RIEN+ LV L+ + L N + KIEN+ L L + +N + + +E L + ++ VL+L+ N I
Sbjct: 72 MRLEFKNILRIDHLWMMPNLTKLCLNCNKIEVIEHLEMLTALKDLNLSFNYITRIENLEKLVKLEKLSLFSNRIRKIENIHTLQNLVILSIGNNLIDTVEGIERLRFVSSLKVLNLEGNPI 192 HSP 2 Score: 53.9138 bits (128), Expect = 3.376e-7 Identity = 53/152 (34.87%), Postives = 77/152 (50.66%), Query Frame = 3
Query: 528 EIEKHKWPRMTTDYL--KKHCKENKLYITPRLNDILYLHYKGFAFIENLDEYVGLRCLFLETNGISKIENLEMLTELRCLYLSKNLISRIENIATLVNLDSIDLSHNL---VAKIENLRNLPKFTKLILAHNKVQKISDLEELIYCDNISVL 968
++E + R+TT L K + + L++ P L L L+ IE+L+ L+ L L N I++IENLE L +L L L N I +IENI TL NL + + +NL V IE LR + L L N + K D +Y I++L
Sbjct: 60 QLEPVVYDRITTMRLEFKNILRIDHLWMMPNLTK-LCLNCNKIEVIEHLEMLTALKDLNLSFNYITRIENLEKLVKLEKLSLFSNRIRKIENIHTLQNLVILSIGNNLIDTVEGIERLRFVSSLKVLNLEGNPIAKQPDFPLSLYV--IAIL 208
BLAST of LRRC50 vs. Ensembl Fly
Match: Ppr-Y (gene:FBgn0046697 transcript:FBtr0346721) HSP 1 Score: 62.7734 bits (151), Expect = 5.478e-10 Identity = 39/102 (38.24%), Postives = 59/102 (57.84%), Query Frame = 3
Query: 684 LRCLFLETNGISKIENLEMLTELRCLYLSKNLISRIENIATLVNLDSIDLSHNLVAKIENLRNLPKFTKLILAHNKVQKISDLEELIYCDNISVLDLQHNQI 989
L L L N I IEN+EMLT L+ L LS N I +IEN+ TLVNL+ + L N + IEN+ L + L +N + + +E + +N+ +++L+ N I
Sbjct: 83 LTKLCLNCNKIETIENIEMLTNLKDLNLSFNFIEKIENLDTLVNLEVLSLFSNKIEAIENIDMLTMLVIISLGNNLIDTVEGIERFRFMNNLKIINLEGNPI 184
BLAST of LRRC50 vs. Ensembl Fly
Match: U2A (gene:FBgn0033210 transcript:FBtr0088941) HSP 1 Score: 57.3806 bits (137), Expect = 1.063e-8 Identity = 46/139 (33.09%), Postives = 80/139 (57.55%), Query Frame = 3
Query: 780 ISRIENI-ATLVNLDSIDLSHNLVAKIENLRNLPKFTKLILAHNKVQKISD-LEELIYCDNISVLDLQHNQIDDPNVIEEI--FAKMKSLRVLYLQGNQFMKNVKNYRKHVINLCKNLTYLDERPVFEKDRACAEAFCR 1184
I +IEN+ ATL D+IDLS N + K++NL +LP+ L+L +N++ +IS+ LEE + N+ + L N + + + +E + F K++++ +L + NYR+++ L LD R + +KDR A+ F R
Sbjct: 31 IPQIENLGATLDQFDTIDLSDNDLRKLDNLPHLPRLKCLLLNNNRILRISEGLEEAV--PNLGSIILTGNNLQELSDLEPLVGFTKLETICLLI----NPVSTKPNYREYMAYKFPQLRLLDFRKIKQKDRQAAQEFFR 163
BLAST of LRRC50 vs. Ensembl Zebrafish
Match: dnaaf1 (dynein, axonemal, assembly factor 1 [Source:NCBI gene;Acc:386722]) HSP 1 Score: 278.485 bits (711), Expect = 1.252e-85 Identity = 149/322 (46.27%), Postives = 207/322 (64.29%), Query Frame = 3
Query: 537 KHKWPRMTTDYLKKHCKENKLYITPRLNDILYLHYKGFAFIENLDEYVGLRCLFLETNGISKIENLEMLTELRCLYLSKNLISRIENIATLVNLDSIDLSHNLVAKIENLRNLPKFTKLILAHNKVQKISDLEELIYCDNISVLDLQHNQIDDPNVIEEIFAKMKSLRVLYLQGNQFMKNVKNYRKHVINLCKNLTYLDERPVFEKDRACAEAFCRGGIEEEKDERNRWVAKEQKRMDDSFEWLRQRR--AKIEAQNHELKLKN---------EKESLGESIADICVKPGEVDWLYGPQEVYDDLTTSNDAIDKSTLDEELD 1469
K PR+T D+L++HCK+NKLY+TPRLND LYLH+KGF+ IE L+EY GLRCL+LE NGI KIENLE TELRCL+L +NLI +EN+ L L ++++S+N + IEN+ +L + L ++HN ++ + D+EEL +C +ISVLDL HN+I DP ++ I KM LRVL L GN+ +K + NYRK +I K LTYLD+RPVF KDRACAEA+ GG+E E+ ER W +E++++ +S + + R A Q+ EL K E +S + I+DI +P E D D T+ + D S E+D
Sbjct: 49 KPSGPRITKDFLREHCKKNKLYLTPRLNDTLYLHFKGFSCIEGLEEYTGLRCLWLECNGIRKIENLENQTELRCLFLHQNLIHTLENLEPLSKLCTLNVSNNYIKVIENISSLSDLSTLQISHNTLENVCDMEELSHCPSISVLDLSHNRISDPALV-NILEKMPDLRVLNLMGNEVIKKIPNYRKTLIVRLKQLTYLDDRPVFPKDRACAEAWAAGGLEGEQKEREMWQTRERRKIQESLDAMTAIRETALKRRQDRELSEKGILEFPSPVAEDQSPHDEISDI--EPAESD---------SDSETTQEQTDASPSPSEMD 358
BLAST of LRRC50 vs. Ensembl Zebrafish
Match: dnaaf1 (dynein, axonemal, assembly factor 1 [Source:NCBI gene;Acc:386722]) HSP 1 Score: 122.479 bits (306), Expect = 3.266e-32 Identity = 60/104 (57.69%), Postives = 79/104 (75.96%), Query Frame = 3
Query: 537 KHKWPRMTTDYLKKHCKENKLYITPRLNDILYLHYKGFAFIENLDEYVGLRCLFLETNGISKIENLEMLTELRCLYLSKNLISRIENIATLVNLDSIDLSHNLV 848
K PR+T D+L++HCK+NKLY+TPRLND LYLH+K E L+EY GLRCL+LE NGI KIENLE TELRCL+L +NLI +EN+ L L ++++S+N +
Sbjct: 49 KPSGPRITKDFLREHCKKNKLYLTPRLNDTLYLHFK-----EGLEEYTGLRCLWLECNGIRKIENLENQTELRCLFLHQNLIHTLENLEPLSKLCTLNVSNNYI 147
BLAST of LRRC50 vs. Ensembl Zebrafish
Match: ppp1r7 (protein phosphatase 1, regulatory (inhibitor) subunit 7 [Source:NCBI gene;Acc:560323]) HSP 1 Score: 73.559 bits (179), Expect = 1.456e-14 Identity = 51/163 (31.29%), Postives = 89/163 (54.60%), Query Frame = 3
Query: 501 EQRKREIDAEIEKHKWPRMTTDYLKKHCKENKLYITPRLNDILYLHYKGFAFIENLDEYVGLRCLFLETNGISKIENLEMLTELRCLYLSKNLISRIENIATLVNLDSIDLSHNLVAKIENLRNLPKFTKLILAHNKVQKISDLEELIYCDNISVLDLQHNQI 989
E +++ ++ E++ + P + + + + + P D+ +H + IE L+ + + + L N I +IENLE L LR L L N I ++EN+ L L+ +D+S NL+ KIE L +L K KL L HNK+ I++L+ L ++ +L+L N+I
Sbjct: 30 ETKRKSLNGEVDSLQAPSTVPE--ESPVDMDTITLDPEEEDVDLVHCR-IGKIEGLEVLLKAKTISLRQNLIKRIENLESLVSLRELDLYDNQIRKLENLQALTELEQLDVSFNLLRKIEGLDSLTKVKKLFLLHNKIASIANLDHLT---SLQMLELGSNRI 186 HSP 2 Score: 58.5362 bits (140), Expect = 1.827e-9 Identity = 37/87 (42.53%), Postives = 52/87 (59.77%), Query Frame = 3
Query: 657 IENLDEYVGLRCLFLETNGISKIENLEMLTELRCLYLSKNLISRIENIATLVNLDSIDLSHNLVAKIENLRNLPKFTKLILAHNKVQ 917
IENL+ V LR L L N I K+ENL+ LTEL L +S NL+ +IE + +L + + L HN +A I NL +L L L N+++
Sbjct: 101 IENLESLVSLRELDLYDNQIRKLENLQALTELEQLDVSFNLLRKIEGLDSLTKVKKLFLLHNKIASIANLDHLTSLQMLELGSNRIR 187
BLAST of LRRC50 vs. Ensembl Zebrafish
Match: ppp1r7 (protein phosphatase 1, regulatory (inhibitor) subunit 7 [Source:NCBI gene;Acc:560323]) HSP 1 Score: 73.1738 bits (178), Expect = 1.760e-13 Identity = 51/163 (31.29%), Postives = 89/163 (54.60%), Query Frame = 3
Query: 501 EQRKREIDAEIEKHKWPRMTTDYLKKHCKENKLYITPRLNDILYLHYKGFAFIENLDEYVGLRCLFLETNGISKIENLEMLTELRCLYLSKNLISRIENIATLVNLDSIDLSHNLVAKIENLRNLPKFTKLILAHNKVQKISDLEELIYCDNISVLDLQHNQI 989
E +++ ++ E++ + P + + + + + P D+ +H + IE L+ + + + L N I +IENLE L LR L L N I ++EN+ L L+ +D+S NL+ KIE L +L K KL L HNK+ I++L+ L ++ +L+L N+I
Sbjct: 27 ETKRKSLNGEVDSLQAPSTVPE--ESPVDMDTITLDPEEEDVDLVHCR-IGKIEGLEVLLKAKTISLRQNLIKRIENLESLVSLRELDLYDNQIRKLENLQALTELEQLDVSFNLLRKIEGLDSLTKVKKLFLLHNKIASIANLDHLT---SLQMLELGSNRI 183 HSP 2 Score: 61.2326 bits (147), Expect = 1.122e-9 Identity = 40/129 (31.01%), Postives = 71/129 (55.04%), Query Frame = 3
Query: 657 IENLDEYVGLRCLFLETNGISKIENLEMLTELRCLYLSKNLISRIENIATLVNLDSIDLSHNLVAKIENLRNLPKFTKLILAHNKVQKISDLEELIYCDNISVLDLQHNQID-DPNVIEEIFAKMKSLR 1040
++NLD L L +++N I+K+E L+ L LR LYLS N I +E + L ++D++ N + KIEN+ +L + + N+++ +DL+EL + + L+ N + DP +I + S+R
Sbjct: 208 LQNLDGLHNLTVLSIQSNRITKLEGLQNLVNLRELYLSHNGIEVMEGLENNKKLSTLDIAANRIKKIENISHLTDLKEFWMNDNQIENWADLDELKNAKGLETVYLERNPLQKDPQYRRKIMLALPSVR 336 HSP 3 Score: 60.4622 bits (145), Expect = 2.081e-9 Identity = 52/183 (28.42%), Postives = 89/183 (48.63%), Query Frame = 3
Query: 627 LYLHYKGFAFIENLDEYVGLRCLFLE----------------------TNGISKIENLEMLTELRCLYLSKNLISRIENIATLVNLDSIDLSHNLVAKIENLRNLPKFTKLILAHNKVQKISDLEELIYCDNISVLDLQHNQIDDPNVIEEIFAKMKSLRVLYLQGNQFMKNVKNYRKHVINL 1109
L+L + A I NLD L+ L L TN I++++NL+ L L L + N I+++E + LVNL + LSHN + +E L N K + L +A N+++KI E + + ++ + NQI++ ++E+ K L +YL+ N K+ + RK ++ L
Sbjct: 154 LFLLHNKIASIANLDHLTSLQMLELGSNRIRVIENLDSLSSLESLFLGTNKITQLQNLDGLHNLTVLSIQSNRITKLEGLQNLVNLRELYLSHNGIEVMEGLENNKKLSTLDIAANRIKKI---ENISHLTDLKEFWMNDNQIENWADLDEL-KNAKGLETVYLERNPLQKDPQYRRKIMLAL 332 HSP 4 Score: 53.1434 bits (126), Expect = 4.352e-7 Identity = 48/139 (34.53%), Postives = 73/139 (52.52%), Query Frame = 3
Query: 657 IENLDEYVGLRCLFLETNGISKIENLEMLTELRCLYLSKNLISRIENIATLVNLDSIDLSHNLVAKIENLRNLPKFTKLILAHNKVQKISDLEELIYCDNISVLDLQHNQIDDPNVIEEIFAKMKSLRVLYLQGNQFMK 1073
IE LD ++ LFL N I+ I NL+ LT L+ L L N I IEN+ +L +L+S+ L N + +++NL L T L + N++ K+ L+ L+ N+ L L HN I+ + E K L L + N+ K
Sbjct: 142 IEGLDSLTKVKKLFLLHNKIASIANLDHLTSLQMLELGSNRIRVIENLDSLSSLESLFLGTNKITQLQNLDGLHNLTVLSIQSNRITKLEGLQNLV---NLRELYLSHNGIE----VMEGLENNKKLSTLDIAANRIKK 273 HSP 5 Score: 51.6026 bits (122), Expect = 1.329e-6 Identity = 49/148 (33.11%), Postives = 80/148 (54.05%), Query Frame = 3
Query: 657 IENLDEYVGLRCLFLETNGISKIENLEMLTELRCLYLSKNLISRIENIATLVNLDSIDLSHNLVAKIENLRNLPKFTKLILAHNKVQKISDLEELIYCDNISVLDLQHNQIDDPNVIEEIFAKMKSLRVLYLQ--GNQFMKNVKNYRK 1094
+ENL L L + N + KIE L+ LT+++ L+L N I+ I N+ L +L ++L N + IENL +L L L NK+ ++ +L+ L N++VL +Q N+I E + +LR LYL G + M+ ++N +K
Sbjct: 120 LENLQALTELEQLDVSFNLLRKIEGLDSLTKVKKLFLLHNKIASIANLDHLTSLQMLELGSNRIRVIENLDSLSSLESLFLGTNKITQLQNLDGL---HNLTVLSIQSNRITKL----EGLQNLVNLRELYLSHNGIEVMEGLENNKK 260
BLAST of LRRC50 vs. Ensembl Zebrafish
Match: drc3 (dynein regulatory complex subunit 3 [Source:ZFIN;Acc:ZDB-GENE-061103-349]) HSP 1 Score: 68.1662 bits (165), Expect = 1.316e-11 Identity = 64/191 (33.51%), Postives = 86/191 (45.03%), Query Frame = 3
Query: 627 LYLHYKGFAFIENLDEYVGLRCLFLETNGISKIENLEMLTELRCLYLSKNLISRIENIATLVNLDSIDLSHNLVAKIENLRNLPKFTKLILAHNKVQKISDLEELIYCDNISVLDLQHNQIDDPNVIEEIFAKMKSLRVLYLQGNQFMKNVKNYRKHVINLCKNLTYLDERPVFEKDRACAEAFCRGGIEE 1199
L L Y+ I +L + L L L+ N I +IE LE LT L L LS N I IE + TLV L + L +N ++ IENL L + L L +N I+ LE +IY + +SLR L L GN + + Y+ V L YLD R + E+ R A A + IEE
Sbjct: 39 LRLDYRNILKIYHLWSFSSLTKLQLDNNAIERIEGLENLTNLTWLDLSFNKIEVIEGLQTLVKLQDLSLFNNRISVIENLDTLQRLQVLSLGNN---SIAQLENVIY-----------------------LRRFQSLRTLNLAGNPICEEDR-YKTFVSAYLPELVYLDYRLLDEQTRETANAKYQYAIEE 202
BLAST of LRRC50 vs. Ensembl Xenopus
Match: ENSXETT00000038727.1 (dynein axonemal assembly factor 1 [Source:NCBI gene;Acc:101730543]) HSP 1 Score: 263.848 bits (673), Expect = 2.150e-82 Identity = 140/267 (52.43%), Postives = 185/267 (69.29%), Query Frame = 3
Query: 534 EKHKWPRMTTDYLKKHCKENKLYITPRLNDILYLHYKGFAFIENLDEYVGLRCLFLETNGISKIENLEMLTELRCLYLSKNLISRIENIATLVNLDSIDLSHNLVAKIENLRNLPKFTKLILAHNKVQKISDLEELIYCDNISVLDLQHNQIDDPNVIEEIFAKMKSLRVLYLQGNQFMKNVKNYRKHVINLCKNLTYLDERPVFEKDRACAEAFCRGGIEEEKDERNRWVAKEQKRMDDSFEWLRQ-RRAKIEAQNHELKLKNEKE 1331
EK PRMT L++ CK+ KLY TP LND LYLHYKGF +ENL+EY GL+CL+LE NG++KIENL+ TELRCL+L +NL+ +IEN+ L LD+++LS+N + IENL L + L +A+N++ + D++ L C +I VLDL HN++DDP VI I KM L VL L GN+ K + NYRK V + LTYLD+RP+F KDRACAEA+ RGG E EKDER +W +E+K++ DS + L + RRA E +N K K EKE
Sbjct: 57 EKETGPRMTKKILREICKQQKLYSTPYLNDTLYLHYKGFMCVENLEEYTGLKCLWLECNGLTKIENLDAQTELRCLFLHQNLVHKIENLDHLQKLDTLNLSNNCIKTIENLSCLKVLSTLQIAYNQLHTLEDVQHLEDCPSIRVLDLSHNKLDDPAVI-NILQKMPDLHVLNLMGNELTKKIPNYRKIVTVQLQKLTYLDDRPIFPKDRACAEAWFRGGREAEKDEREQWETRERKKIQDSIDALSEIRRAAEERRNQ--KEKEEKE 320
BLAST of LRRC50 vs. Ensembl Xenopus
Match: ENSXETT00000038732.1 (dynein axonemal assembly factor 1 [Source:NCBI gene;Acc:101730543]) HSP 1 Score: 269.24 bits (687), Expect = 2.455e-81 Identity = 141/276 (51.09%), Postives = 188/276 (68.12%), Query Frame = 3
Query: 534 EKHKWPRMTTDYLKKHCKENKLYITPRLNDILYLHYKGFAFIENLDEYVGLRCLFLETNGISKIENLEMLTELRCLYLSKNLISRIENIATLVNLDSIDLSHNLVAKIENLRNLPKFTKLILAHNKVQKISDLEELIYCDNISVLDLQHNQIDDPNVIEEIFAKMKSLRVLYLQGNQFMKNVKNYRKHVINLCKNLTYLDERPVFEKDRACAEAFCRGGIEEEKDERNRWVAKEQKRMDDSFEWLRQ-RRAKIEAQNHELKLKNEKESLGESIADI 1358
EK PRMT L++ CK+ KLY TP LND LYLHYKGF +ENL+EY GL+CL+LE NG++KIENL+ TELRCL+L +NL+ +IEN+ L LD+++LS+N + IENL L + L +A+N++ + D++ L C +I VLDL HN++DDP VI I KM L VL L GN+ K + NYRK V + LTYLD+RP+F KDRACAEA+ RGG E EKDER +W +E+K++ DS + L + RRA E +N + EKE GE +I
Sbjct: 57 EKETGPRMTKKILREICKQQKLYSTPYLNDTLYLHYKGFMCVENLEEYTGLKCLWLECNGLTKIENLDAQTELRCLFLHQNLVHKIENLDHLQKLDTLNLSNNCIKTIENLSCLKVLSTLQIAYNQLHTLEDVQHLEDCPSIRVLDLSHNKLDDPAVI-NILQKMPDLHVLNLMGNELTKKIPNYRKIVTVQLQKLTYLDDRPIFPKDRACAEAWFRGGREAEKDEREQWETRERKKIQDSIDALSEIRRAAEERRN-----QKEKEEKGEQPKEI 326
BLAST of LRRC50 vs. Ensembl Xenopus
Match: rbpms2 (RNA binding protein with multiple splicing 2 [Source:Xenbase;Acc:XB-GENE-490341]) HSP 1 Score: 80.1073 bits (196), Expect = 4.347e-15 Identity = 69/229 (30.13%), Postives = 108/229 (47.16%), Query Frame = 3
Query: 624 ILYLHYKGFAFIENLDEYVGLRCLFLETNGISKIENLEMLTELRCLYLSKNLISRIENIATLVNLDSIDLSHNLVAKIENLRNLPKFTKLILAHNKVQKISDLEELIYCDNISVLDLQHNQID----------------DPNVIEEI-----FAKMKSLRVLYLQGNQFMKNVKNYRKHVINLCKNLTYLDERPVFEKDRACAEAFCRGGIEEEKDERNRWVAKEQKRM 1247
+LYLH+ I+NL L L L N I +I L L LR L L KN I +I N+ L NLD +DL N +AKIEN+ +L + L LA N++ ++ ++ L D++ L+L+ N+I N I I A SL + L GN + YR+ ++ L LD + + E++R A R E +++ + + KE++R+
Sbjct: 192 LLYLHHNSITRIQNLSSLQHLIFLDLYDNNIEEISGLSSLRSLRVLMLGKNRIQKISNLENLKNLDVLDLHGNQIAKIENVSHLRELRVLNLARNQINQVENINGL---DSLKELNLRDNKITFLRDVDTLPSLQLLYLSFNNISRINDILCLADSTSLSDVTLDGNPIAQE-SWYRQTILGHMLQLRQLDMKRITEEERRTASVLARKEDERKRESHKQALLKEKRRI 416 HSP 2 Score: 65.855 bits (159), Expect = 1.213e-10 Identity = 45/107 (42.06%), Postives = 65/107 (60.75%), Query Frame = 3
Query: 747 ELRCLYLSKNLISRIENIATLVNLDSIDLSHNLVAKIENLRNLPKFTKLILAHNKVQKISDLEELIYCDNISVLDLQHNQIDDPNVIEEIFAKMKSLRVLYLQGNQF 1067
+LR LYL N I+RI+N+++L +L +DL N + +I L +L L+L N++QKIS+LE L N+ VLDL NQI IE + + ++ LRVL L NQ
Sbjct: 189 QLRLLYLHHNSITRIQNLSSLQHLIFLDLYDNNIEEISGLSSLRSLRVLMLGKNRIQKISNLENL---KNLDVLDLHGNQIAK---IENV-SHLRELRVLNLARNQI 288
BLAST of LRRC50 vs. Ensembl Xenopus
Match: rbpms2 (RNA binding protein with multiple splicing 2 [Source:Xenbase;Acc:XB-GENE-490341]) HSP 1 Score: 78.9518 bits (193), Expect = 9.010e-15 Identity = 71/227 (31.28%), Postives = 107/227 (47.14%), Query Frame = 3
Query: 624 ILYLHYKGFAFIENLDEYVGLRCLFLETNGISKIENLEMLTELRCLYLSKNLISRIENIATLVNLDSIDLSHNLVAKIENLRNLPKFTKLILAHNKVQKISD------LEELIYCDN-------------ISVLDLQHNQIDDPNVIEEIFAKMKSLRVLYLQGNQFMKNVKNYRKHVINLCKNLTYLDERPVFEKDRACAEAFCRGGIEEEKDERNRWVAKEQKRM 1247
+LYLH+ I+NL L L L N I +I L L LR L L KN I +I N+ L NLD +DL N +AKIEN+ +L + L LA N++ ++ + L+EL DN + +L L N I N I A SL + L GN + YR+ ++ L LD + + E++R A R E +++ + + KE++R+
Sbjct: 49 LLYLHHNSITRIQNLSSLQHLIFLDLYDNNIEEISGLSSLRSLRVLMLGKNRIQKISNLENLKNLDVLDLHGNQIAKIENVSHLRELRVLNLARNQINQVENINGLDSLKELNLRDNKITFLRDVDTLPSLQLLYLSFNNISRINDI-LCLADSTSLSDVTLDGNPIAQE-SWYRQTILGHMLQLRQLDMKRITEEERRTASVLARKEDERKRESHKQALLKEKRRI 273 HSP 2 Score: 67.3958 bits (163), Expect = 3.589e-11 Identity = 51/130 (39.23%), Postives = 75/130 (57.69%), Query Frame = 3
Query: 678 VGLRCLFLETNGISKIENLEMLTELRCLYLSKNLISRIENIATLVNLDSIDLSHNLVAKIENLRNLPKFTKLILAHNKVQKISDLEELIYCDNISVLDLQHNQIDDPNVIEEIFAKMKSLRVLYLQGNQF 1067
V + CLF N ++ +E +LR LYL N I+RI+N+++L +L +DL N + +I L +L L+L N++QKIS+LE L N+ VLDL NQI IE + + ++ LRVL L NQ
Sbjct: 24 VQVVCLFFRQN-LTVCPIIEGEEQLRLLYLHHNSITRIQNLSSLQHLIFLDLYDNNIEEISGLSSLRSLRVLMLGKNRIQKISNLENL---KNLDVLDLHGNQIAK---IENV-SHLRELRVLNLARNQI 145
BLAST of LRRC50 vs. Ensembl Xenopus
Match: rbpms2 (RNA binding protein with multiple splicing 2 [Source:Xenbase;Acc:XB-GENE-490341]) HSP 1 Score: 78.1814 bits (191), Expect = 1.934e-14 Identity = 70/232 (30.17%), Postives = 109/232 (46.98%), Query Frame = 3
Query: 624 ILYLHYKGFAFIENLDEYVGLRCLFLETNGISKIENLEMLTELRCLYLSKNLISRIENIATLVNLDSIDLSHNLVAKIENLRNLPKFTKLILAHNKVQKISDLEELIYCDNISVLDLQHNQID----------------DPNVIEEI-----FAKMKSLRVLYLQGNQFMKNVKNYRKHVINLCKNLTYLDERPVFEKDRACAEAFCRGGIEEEKDERNRWVAKEQKRMDDS 1256
+LYLH+ I+NL L L L N I +I L L LR L L KN I +I N+ L NLD +DL N +AKIEN+ +L + L LA N++ ++ ++ L D++ L+L+ N+I N I I A SL + L GN + YR+ ++ L LD + + E++R A R E +++ + + KE++R+ S
Sbjct: 116 LLYLHHNSITRIQNLSSLQHLIFLDLYDNNIEEISGLSSLRSLRVLMLGKNRIQKISNLENLKNLDVLDLHGNQIAKIENVSHLRELRVLNLARNQINQVENINGL---DSLKELNLRDNKITFLRDVDTLPSLQLLYLSFNNISRINDILCLADSTSLSDVTLDGNPIAQE-SWYRQTILGHMLQLRQLDMKRITEEERRTASVLARKEDERKRESHKQALLKEKRRIAIS 343 HSP 2 Score: 67.0106 bits (162), Expect = 5.682e-11 Identity = 50/126 (39.68%), Postives = 73/126 (57.94%), Query Frame = 3
Query: 690 CLFLETNGISKIENLEMLTELRCLYLSKNLISRIENIATLVNLDSIDLSHNLVAKIENLRNLPKFTKLILAHNKVQKISDLEELIYCDNISVLDLQHNQIDDPNVIEEIFAKMKSLRVLYLQGNQF 1067
CLF N ++ +E +LR LYL N I+RI+N+++L +L +DL N + +I L +L L+L N++QKIS+LE L N+ VLDL NQI IE + + ++ LRVL L NQ
Sbjct: 95 CLFFRQN-LTVCPIIEGEEQLRLLYLHHNSITRIQNLSSLQHLIFLDLYDNNIEEISGLSSLRSLRVLMLGKNRIQKISNLENL---KNLDVLDLHGNQIAK---IENV-SHLRELRVLNLARNQI 212
BLAST of LRRC50 vs. Ensembl Mouse
Match: Dnaaf1 (dynein, axonemal assembly factor 1 [Source:MGI Symbol;Acc:MGI:1915520]) HSP 1 Score: 273.863 bits (699), Expect = 4.292e-83 Identity = 130/250 (52.00%), Postives = 177/250 (70.80%), Query Frame = 3
Query: 543 KWPRMTTDYLKKHCKENKLYITPRLNDILYLHYKGFAFIENLDEYVGLRCLFLETNGISKIENLEMLTELRCLYLSKNLISRIENIATLVNLDSIDLSHNLVAKIENLRNLPKFTKLILAHNKVQKISDLEELIYCDNISVLDLQHNQIDDPNVIEEIFAKMKSLRVLYLQGNQFMKNVKNYRKHVINLCKNLTYLDERPVFEKDRACAEAFCRGGIEEEKDERNRWVAKEQKRMDDSFEWLR--QRRAK 1286
+ PRMT +L+K CK++KLY+TP LND LYLH+KGF IENL+EY GLRCL+LE NGI +IENL+ +ELRCL+L NL+ +IEN+ L LD+++LS+N + IENL LP L +AHN+++ ++D+E L C + VLDL HN + DP ++ + M LRVL L GN K++ NYR+ V K+LTYLD+RPVF KDRACAEA+ RGG EK+ER +W ++E K++ DS E L +RRA+
Sbjct: 78 RGPRMTKQFLQKLCKQHKLYVTPALNDTLYLHFKGFDRIENLEEYTGLRCLWLECNGIQRIENLQAQSELRCLFLQVNLLHKIENLEPLQKLDALNLSNNYIKTIENLSCLPVLNTLQMAHNRLETVADIEHLRECLRLCVLDLSHNALSDPEIL-SVLESMPCLRVLNLMGNPVTKHIPNYRRTVTVRLKHLTYLDDRPVFPKDRACAEAWARGGYAAEKEERRQWESREHKKITDSLEALAMIKRRAE 326
BLAST of LRRC50 vs. Ensembl Mouse
Match: Ppp1r7 (protein phosphatase 1, regulatory subunit 7 [Source:MGI Symbol;Acc:MGI:1913635]) HSP 1 Score: 70.0922 bits (170), Expect = 1.751e-12 Identity = 53/160 (33.12%), Postives = 88/160 (55.00%), Query Frame = 3
Query: 624 ILYLHYKGFAFIENLDEYVGLRCLFLETNGISKIENLEMLTELRCLYLSKNLISRIENIATLVNLDSIDLSHNLVAKIENLRNLPKFTKLILAHNKVQKISDLEELIYCDNISVLDLQHNQIDDPNVIEEIFAKMKSLRVLYLQGNQFMKNVKNYRKHVI 1103
+L L IEN+D L LFL N I+K++NL+ LT L L + N +++IE + +LVNL + LS+N + IE L N K T L +A N+++KI ++ L + D N ++ + ++E+ +SL +YL+ N K+ + YR+ V+
Sbjct: 191 MLELGSNRIRAIENIDTLTNLESLFLGKNKITKLQNLDALTNLTVLSVQSNRLAKIEGLQSLVNLRELYLSNNGIEVIEGLENNNKLTMLDIASNRIKKIENISHLTELQEFWMND---NLLESWSDLDELKGA-RSLETVYLERNPLQKDPQ-YRRKVM 345 HSP 2 Score: 68.9366 bits (167), Expect = 4.799e-12 Identity = 47/124 (37.90%), Postives = 71/124 (57.26%), Query Frame = 3
Query: 621 DILYLHYKGFAFIENLDEYVGLRCLFLETNGISKIENLEMLTELRCLYLSKNLISRIENIATLVNLDSIDLSHNLVAKIENLRNLPKFTKLILAHNKVQKISDLEELIYCDNISVLDLQHNQID 992
++L + + IE +D+ L+ LFL N I+KIEN+ L +L+ L L N I IENI TL NL+S+ L N + K++NL L T L + N++ KI L+ L+ N+ L L +N I+
Sbjct: 146 EVLDISFNMLRNIEGIDKLTQLKKLFLVNNKINKIENISNLHQLQMLELGSNRIRAIENIDTLTNLESLFLGKNKITKLQNLDALTNLTVLSVQSNRLAKIEGLQSLV---NLRELYLSNNGIE 266 HSP 3 Score: 67.0106 bits (162), Expect = 1.783e-11 Identity = 56/154 (36.36%), Postives = 77/154 (50.00%), Query Frame = 3
Query: 657 IENLDEYVGLRCLFLETNGISKIENLEMLTELRCLYLSKNLISRIENIATLVNLDSIDLSHNLVAKIENLRNLPKFTKLILAHNKVQ-------------------KISDLEELIYCDNISVLDLQHNQIDDPNVIEEIFAKMKSLRVLYLQGN 1061
IENL+E LR L L N I KIENLE LTEL L +S N++ IE I L L + L +N + KIEN+ NL + L L N+++ KI+ L+ L N++VL +Q N++ E + +LR LYL N
Sbjct: 114 IENLEELQSLRELDLYDNQIKKIENLEALTELEVLDISFNMLRNIEGIDKLTQLKKLFLVNNKINKIENISNLHQLQMLELGSNRIRAIENIDTLTNLESLFLGKNKITKLQNLDALTNLTVLSVQSNRLAKI----EGLQSLVNLRELYLSNN 263 HSP 4 Score: 62.7734 bits (151), Expect = 5.073e-10 Identity = 43/139 (30.94%), Postives = 74/139 (53.24%), Query Frame = 3
Query: 627 LYLHYKGFAFIENLDEYVGLRCLFLETNGISKIENLEMLTELRCLYLSKNLISRIENIATLVNLDSIDLSHNLVAKIENLRNLPKFTKLILAHNKVQKISDLEELIYCDNISVLDLQHNQID-DPNVIEEIFAKMKSLR 1040
L+L ++NLD L L +++N ++KIE L+ L LR LYLS N I IE + L +D++ N + KIEN+ +L + + + N ++ SDL+EL ++ + L+ N + DP ++ + S+R
Sbjct: 214 LFLGKNKITKLQNLDALTNLTVLSVQSNRLAKIEGLQSLVNLRELYLSNNGIEVIEGLENNNKLTMLDIASNRIKKIENISHLTELQEFWMNDNLLESWSDLDELKGARSLETVYLERNPLQKDPQYRRKVMLALPSVR 352
BLAST of LRRC50 vs. Ensembl Mouse
Match: Lrrc49 (leucine rich repeat containing 49 [Source:MGI Symbol;Acc:MGI:2442689]) HSP 1 Score: 67.3958 bits (163), Expect = 3.365e-11 Identity = 70/238 (29.41%), Postives = 114/238 (47.90%), Query Frame = 3
Query: 657 IENLDEYVGLRCLFLETNGISKIENLEMLTELRCLYLSKNLISRIENIATLVNLDSIDLSHNLVAKIENLRNLPKFTKLILAHNKVQKISDLEELIYCDNISVLDLQHNQI------DDPNVIEEIF---------------AKMKSLRVLYLQGNQFMKNVKNYRKHVINLCKNLTYLDERPVFEKDRACAEAFCRGGIEEEKDERNRWVAKEQKRM---DDSFEW-LRQRRAKIEA 1295
I+N+ L L L N I +I L L LR L L KN I +I N+ L NLD +DL N + KIEN+ +L L LA N + + +L L D+++ L+L+HNQI D+ ++ +F A+ SL + GN + Y+ V+ L LD + + E++R A + E++++ + + KE+KR+ + + +W L+QR A I +
Sbjct: 187 IQNISNLQRLIFLDLYDNQIEEISGLSTLKSLRVLLLGKNRIKKISNLENLKNLDVLDLHGNQITKIENVNHLCDLRVLNLARNLLSHVDNLNGL---DSLTELNLRHNQITFVRDVDNLPCLQRLFLSFNNITSFESVSCLAESTSLSDITFDGNPIAQE-SWYKHTVLQNMMQLRQLDMKRITEEERRVASVVAKKEEEKKRESHKQSLLKEKKRLTINNVARKWDLQQRVANIAS 420 HSP 2 Score: 55.4546 bits (132), Expect = 1.959e-7 Identity = 34/81 (41.98%), Postives = 46/81 (56.79%), Query Frame = 3
Query: 747 ELRCLYLSKNLISRIENIATLVNLDSIDLSHNLVAKIENLRNLPKFTKLILAHNKVQKISDLEELIYCDNISVLDLQHNQI 989
LR L N I+RI+NI+ L L +DL N + +I L L L+L N+++KIS+LE L N+ VLDL NQI
Sbjct: 173 HLRLLNFQHNFITRIQNISNLQRLIFLDLYDNQIEEISGLSTLKSLRVLLLGKNRIKKISNLENL---KNLDVLDLHGNQI 250
BLAST of LRRC50 vs. Ensembl Mouse
Match: Lrrc49 (leucine rich repeat containing 49 [Source:MGI Symbol;Acc:MGI:2442689]) HSP 1 Score: 67.3958 bits (163), Expect = 3.409e-11 Identity = 70/238 (29.41%), Postives = 114/238 (47.90%), Query Frame = 3
Query: 657 IENLDEYVGLRCLFLETNGISKIENLEMLTELRCLYLSKNLISRIENIATLVNLDSIDLSHNLVAKIENLRNLPKFTKLILAHNKVQKISDLEELIYCDNISVLDLQHNQI------DDPNVIEEIF---------------AKMKSLRVLYLQGNQFMKNVKNYRKHVINLCKNLTYLDERPVFEKDRACAEAFCRGGIEEEKDERNRWVAKEQKRM---DDSFEW-LRQRRAKIEA 1295
I+N+ L L L N I +I L L LR L L KN I +I N+ L NLD +DL N + KIEN+ +L L LA N + + +L L D+++ L+L+HNQI D+ ++ +F A+ SL + GN + Y+ V+ L LD + + E++R A + E++++ + + KE+KR+ + + +W L+QR A I +
Sbjct: 193 IQNISNLQRLIFLDLYDNQIEEISGLSTLKSLRVLLLGKNRIKKISNLENLKNLDVLDLHGNQITKIENVNHLCDLRVLNLARNLLSHVDNLNGL---DSLTELNLRHNQITFVRDVDNLPCLQRLFLSFNNITSFESVSCLAESTSLSDITFDGNPIAQE-SWYKHTVLQNMMQLRQLDMKRITEEERRVASVVAKKEEEKKRESHKQSLLKEKKRLTINNVARKWDLQQRVANIAS 426 HSP 2 Score: 55.4546 bits (132), Expect = 1.999e-7 Identity = 34/81 (41.98%), Postives = 46/81 (56.79%), Query Frame = 3
Query: 747 ELRCLYLSKNLISRIENIATLVNLDSIDLSHNLVAKIENLRNLPKFTKLILAHNKVQKISDLEELIYCDNISVLDLQHNQI 989
LR L N I+RI+NI+ L L +DL N + +I L L L+L N+++KIS+LE L N+ VLDL NQI
Sbjct: 179 HLRLLNFQHNFITRIQNISNLQRLIFLDLYDNQIEEISGLSTLKSLRVLLLGKNRIKKISNLENL---KNLDVLDLHGNQI 256
BLAST of LRRC50 vs. Ensembl Mouse
Match: Lrrc49 (leucine rich repeat containing 49 [Source:MGI Symbol;Acc:MGI:2442689]) HSP 1 Score: 66.6254 bits (161), Expect = 5.200e-11 Identity = 70/238 (29.41%), Postives = 114/238 (47.90%), Query Frame = 3
Query: 657 IENLDEYVGLRCLFLETNGISKIENLEMLTELRCLYLSKNLISRIENIATLVNLDSIDLSHNLVAKIENLRNLPKFTKLILAHNKVQKISDLEELIYCDNISVLDLQHNQI------DDPNVIEEIF---------------AKMKSLRVLYLQGNQFMKNVKNYRKHVINLCKNLTYLDERPVFEKDRACAEAFCRGGIEEEKDERNRWVAKEQKRM---DDSFEW-LRQRRAKIEA 1295
I+N+ L L L N I +I L L LR L L KN I +I N+ L NLD +DL N + KIEN+ +L L LA N + + +L L D+++ L+L+HNQI D+ ++ +F A+ SL + GN + Y+ V+ L LD + + E++R A + E++++ + + KE+KR+ + + +W L+QR A I +
Sbjct: 127 IQNISNLQRLIFLDLYDNQIEEISGLSTLKSLRVLLLGKNRIKKISNLENLKNLDVLDLHGNQITKIENVNHLCDLRVLNLARNLLSHVDNLNGL---DSLTELNLRHNQITFVRDVDNLPCLQRLFLSFNNITSFESVSCLAESTSLSDITFDGNPIAQE-SWYKHTVLQNMMQLRQLDMKRITEEERRVASVVAKKEEEKKRESHKQSLLKEKKRLTINNVARKWDLQQRVANIAS 360 HSP 2 Score: 55.0694 bits (131), Expect = 2.062e-7 Identity = 34/81 (41.98%), Postives = 46/81 (56.79%), Query Frame = 3
Query: 747 ELRCLYLSKNLISRIENIATLVNLDSIDLSHNLVAKIENLRNLPKFTKLILAHNKVQKISDLEELIYCDNISVLDLQHNQI 989
LR L N I+RI+NI+ L L +DL N + +I L L L+L N+++KIS+LE L N+ VLDL NQI
Sbjct: 113 HLRLLNFQHNFITRIQNISNLQRLIFLDLYDNQIEEISGLSTLKSLRVLLLGKNRIKKISNLENL---KNLDVLDLHGNQI 190
BLAST of LRRC50 vs. UniProt/SwissProt
Match: sp|Q7ZV84|DAAF1_DANRE (Dynein assembly factor 1, axonemal OS=Danio rerio OX=7955 GN=dnaaf1 PE=2 SV=2) HSP 1 Score: 278.1 bits (710), Expect = 1.272e-84 Identity = 149/322 (46.27%), Postives = 206/322 (63.98%), Query Frame = 3
Query: 537 KHKWPRMTTDYLKKHCKENKLYITPRLNDILYLHYKGFAFIENLDEYVGLRCLFLETNGISKIENLEMLTELRCLYLSKNLISRIENIATLVNLDSIDLSHNLVAKIENLRNLPKFTKLILAHNKVQKISDLEELIYCDNISVLDLQHNQIDDPNVIEEIFAKMKSLRVLYLQGNQFMKNVKNYRKHVINLCKNLTYLDERPVFEKDRACAEAFCRGGIEEEKDERNRWVAKEQKRMDDSFEWLRQRR--AKIEAQNHELKLKN---------EKESLGESIADICVKPGEVDWLYGPQEVYDDLTTSNDAIDKSTLDEELD 1469
K PR+T D+L++HCK+NKLY+TPRLND LYLH+KGF+ IE L+EY GLRCL+LE NGI KIENLE TELRCL+L +NLI +EN+ L L ++++S+N + IEN+ +L + L ++HN + + D+EEL +C +ISVLDL HN+I DP ++ I KM LRVL L GN+ +K + NYRK +I K LTYLD+RPVF KDRACAEA+ GG+E E+ ER W +E++++ +S + + R A Q+ EL K E +S + I+DI +P E D D T+ + D S E+D
Sbjct: 49 KPSGPRITKDFLREHCKKNKLYLTPRLNDTLYLHFKGFSCIEGLEEYTGLRCLWLECNGIRKIENLENQTELRCLFLHQNLIHTLENLEPLSKLCTLNVSNNYIKVIENISSLSDLSTLQISHNTLGNVCDMEELSHCPSISVLDLSHNRISDPALV-NILEKMPDLRVLNLMGNEVIKKIPNYRKTLIVRLKQLTYLDDRPVFPKDRACAEAWAAGGLEGEQKEREMWQTRERRKIQESLDAMTAIRETALKRRQDRELSEKGIIEFPSPVAEDQSPHDEISDI--EPAESD---------SDSETTQEQTDASPSPSEMD 358
BLAST of LRRC50 vs. UniProt/SwissProt
Match: sp|Q9D2H9|DAAF1_MOUSE (Dynein assembly factor 1, axonemal OS=Mus musculus OX=10090 GN=Dnaaf1 PE=1 SV=1) HSP 1 Score: 273.863 bits (699), Expect = 3.003e-82 Identity = 130/250 (52.00%), Postives = 177/250 (70.80%), Query Frame = 3
Query: 543 KWPRMTTDYLKKHCKENKLYITPRLNDILYLHYKGFAFIENLDEYVGLRCLFLETNGISKIENLEMLTELRCLYLSKNLISRIENIATLVNLDSIDLSHNLVAKIENLRNLPKFTKLILAHNKVQKISDLEELIYCDNISVLDLQHNQIDDPNVIEEIFAKMKSLRVLYLQGNQFMKNVKNYRKHVINLCKNLTYLDERPVFEKDRACAEAFCRGGIEEEKDERNRWVAKEQKRMDDSFEWLR--QRRAK 1286
+ PRMT +L+K CK++KLY+TP LND LYLH+KGF IENL+EY GLRCL+LE NGI +IENL+ +ELRCL+L NL+ +IEN+ L LD+++LS+N + IENL LP L +AHN+++ ++D+E L C + VLDL HN + DP ++ + M LRVL L GN K++ NYR+ V K+LTYLD+RPVF KDRACAEA+ RGG EK+ER +W ++E K++ DS E L +RRA+
Sbjct: 78 RGPRMTKQFLQKLCKQHKLYVTPALNDTLYLHFKGFDRIENLEEYTGLRCLWLECNGIQRIENLQAQSELRCLFLQVNLLHKIENLEPLQKLDALNLSNNYIKTIENLSCLPVLNTLQMAHNRLETVADIEHLRECLRLCVLDLSHNALSDPEIL-SVLESMPCLRVLNLMGNPVTKHIPNYRRTVTVRLKHLTYLDDRPVFPKDRACAEAWARGGYAAEKEERRQWESREHKKITDSLEALAMIKRRAE 326
BLAST of LRRC50 vs. UniProt/SwissProt
Match: sp|Q6AYH9|DAAF1_RAT (Dynein assembly factor 1, axonemal OS=Rattus norvegicus OX=10116 GN=Dnaaf1 PE=1 SV=1) HSP 1 Score: 273.863 bits (699), Expect = 3.619e-82 Identity = 130/249 (52.21%), Postives = 177/249 (71.08%), Query Frame = 3
Query: 546 WPRMTTDYLKKHCKENKLYITPRLNDILYLHYKGFAFIENLDEYVGLRCLFLETNGISKIENLEMLTELRCLYLSKNLISRIENIATLVNLDSIDLSHNLVAKIENLRNLPKFTKLILAHNKVQKISDLEELIYCDNISVLDLQHNQIDDPNVIEEIFAKMKSLRVLYLQGNQFMKNVKNYRKHVINLCKNLTYLDERPVFEKDRACAEAFCRGGIEEEKDERNRWVAKEQKRMDDSFEWLR--QRRAK 1286
PRMT +L+K CK++KLY+TP LND LYLH+KGF IENL+EY GLRCL+LE NGI +IENL+ +ELRCL+L NL+ +IEN+ L LD+++LS+N + IENL LP L +AHN+++ ++D+E L C + VLDL HN + DP ++ + M LRVL L GN K++ NYR+ V K+LTYLD+RPVF KDRACAEA+ RGG EK+ER++W ++E K++ DS E L +RRA+
Sbjct: 79 GPRMTKQFLQKLCKQHKLYVTPALNDTLYLHFKGFDRIENLEEYTGLRCLWLECNGIQRIENLQAQSELRCLFLQVNLLHKIENLEPLQKLDALNLSNNYIKTIENLSCLPVLNTLQMAHNRLETVADIEHLRECLQLCVLDLSHNSLSDPEIL-SVLETMPCLRVLNLMGNPVTKHIPNYRRTVTVRLKHLTYLDDRPVFPKDRACAEAWARGGYAAEKEERHQWESREHKKITDSLEALAMIKRRAE 326
BLAST of LRRC50 vs. UniProt/SwissProt
Match: sp|Q8NEP3|DAAF1_HUMAN (Dynein assembly factor 1, axonemal OS=Homo sapiens OX=9606 GN=DNAAF1 PE=1 SV=5) HSP 1 Score: 276.174 bits (705), Expect = 3.763e-82 Identity = 136/267 (50.94%), Postives = 183/267 (68.54%), Query Frame = 3
Query: 543 KWPRMTTDYLKKHCKENKLYITPRLNDILYLHYKGFAFIENLDEYVGLRCLFLETNGISKIENLEMLTELRCLYLSKNLISRIENIATLVNLDSIDLSHNLVAKIENLRNLPKFTKLILAHNKVQKISDLEELIYCDNISVLDLQHNQIDDPNVIEEIFAKMKSLRVLYLQGNQFMKNVKNYRKHVINLCKNLTYLDERPVFEKDRACAEAFCRGGIEEEKDERNRWVAKEQKRMDDSFEWLRQRRAKIEAQNHELKLKNEKESLGE 1343
+ PRMT L+K CK++KLYITP LND LYLH+KGF IENL+EY GLRCL+L++NGI KIENLE TELRCL+L NL+ +IEN+ L LD+++LS+N + IENL LP L +AHN ++ + D++ L C + VLDL HN++ DP ++ I M LRVL L GN ++ + NYR+ V K+LTYLD+RPVF KDRACAEA+ RGG EK+ER +W ++E+K++ DS E L A I+ + E K + E + GE
Sbjct: 84 RGPRMTKSSLQKLCKQHKLYITPALNDTLYLHFKGFDRIENLEEYTGLRCLWLQSNGIQKIENLEAQTELRCLFLQMNLLRKIENLEPLQKLDALNLSNNYIKTIENLSCLPVLNTLQMAHNHLETVEDIQHLQECLRLCVLDLSHNKLSDPEIL-SILESMPDLRVLNLMGNPVIRQIPNYRRTVTVRLKHLTYLDDRPVFPKDRACAEAWARGGYAAEKEERQQWESRERKKITDSIEAL----AMIKQRAEERKRQRESQERGE 345
BLAST of LRRC50 vs. UniProt/SwissProt
Match: sp|B6D5P6|DAAF1_PERCA (Dynein assembly factor 1, axonemal OS=Peromyscus californicus OX=42520 GN=Dnaaf1 PE=2 SV=1) HSP 1 Score: 271.552 bits (693), Expect = 2.192e-81 Identity = 130/250 (52.00%), Postives = 177/250 (70.80%), Query Frame = 3
Query: 543 KWPRMTTDYLKKHCKENKLYITPRLNDILYLHYKGFAFIENLDEYVGLRCLFLETNGISKIENLEMLTELRCLYLSKNLISRIENIATLVNLDSIDLSHNLVAKIENLRNLPKFTKLILAHNKVQKISDLEELIYCDNISVLDLQHNQIDDPNVIEEIFAKMKSLRVLYLQGNQFMKNVKNYRKHVINLCKNLTYLDERPVFEKDRACAEAFCRGGIEEEKDERNRWVAKEQKRMDDSFEWLR--QRRAK 1286
+ PRMT ++L+K CK++KLYITP LND LYLH+KGF IENL+EY GLRCL+LE NGI +IENL+ +ELRCL+L NL+ +IEN+ L LD+++LS+N + IENL LP L +AHN+++ ++D++ L C + VLDL HN + DP ++ + M LRVL L GN K++ NYR+ V K LTYLD+RPVF KDRACAEA+ RGG EK+ER +W ++E K++ DS E L +RRA+
Sbjct: 78 RGPRMTKEFLQKLCKQHKLYITPALNDTLYLHFKGFDRIENLEEYTGLRCLWLECNGIQRIENLQAQSELRCLFLQVNLLHKIENLEPLQKLDALNLSNNYIKTIENLSCLPVLNTLQMAHNRLETVADIQHLGECLRLCVLDLSHNMLSDPEIL-SVLESMPCLRVLNLMGNPVTKHIPNYRRTVTVRLKQLTYLDDRPVFPKDRACAEAWARGGYAAEKEERLQWESREHKKITDSLEALAMIKRRAE 326
BLAST of LRRC50 vs. TrEMBL
Match: A0A0H3YFP8 (Dynein assembly factor 1, axonemal homolog (Fragment) OS=Schmidtea mediterranea OX=79327 GN=LRRC50 PE=2 SV=1) HSP 1 Score: 1202.58 bits (3110), Expect = 0.000e+0 Identity = 594/594 (100.00%), Postives = 594/594 (100.00%), Query Frame = 3
Query: 3 LICLTSNLPRKLGYDFFVLSYIVNKMNCNCDNFDCSMEDLKLISETTPISSVEEIDFKQENCVLDQKLDEIECENDMPSEYNFNSTNNNECDENEELIDENFNHNLNLKICDDETFNTCINAIEDPLKSSMCLDLSILTNISDDMEDEKIIQHPFNDISNINKEEKEQRKREIDAEIEKHKWPRMTTDYLKKHCKENKLYITPRLNDILYLHYKGFAFIENLDEYVGLRCLFLETNGISKIENLEMLTELRCLYLSKNLISRIENIATLVNLDSIDLSHNLVAKIENLRNLPKFTKLILAHNKVQKISDLEELIYCDNISVLDLQHNQIDDPNVIEEIFAKMKSLRVLYLQGNQFMKNVKNYRKHVINLCKNLTYLDERPVFEKDRACAEAFCRGGIEEEKDERNRWVAKEQKRMDDSFEWLRQRRAKIEAQNHELKLKNEKESLGESIADICVKPGEVDWLYGPQEVYDDLTTSNDAIDKSTLDEELDRPNSIFQIYTQNPEIPELVPSESFSSPKRILIQEVTTDVEETITLEPSCQNKMANKTAPIKAFLNESTNETREKNLEKIENLAAQAGSTCKNPFENDFLEIDSLE 1784
LICLTSNLPRKLGYDFFVLSYIVNKMNCNCDNFDCSMEDLKLISETTPISSVEEIDFKQENCVLDQKLDEIECENDMPSEYNFNSTNNNECDENEELIDENFNHNLNLKICDDETFNTCINAIEDPLKSSMCLDLSILTNISDDMEDEKIIQHPFNDISNINKEEKEQRKREIDAEIEKHKWPRMTTDYLKKHCKENKLYITPRLNDILYLHYKGFAFIENLDEYVGLRCLFLETNGISKIENLEMLTELRCLYLSKNLISRIENIATLVNLDSIDLSHNLVAKIENLRNLPKFTKLILAHNKVQKISDLEELIYCDNISVLDLQHNQIDDPNVIEEIFAKMKSLRVLYLQGNQFMKNVKNYRKHVINLCKNLTYLDERPVFEKDRACAEAFCRGGIEEEKDERNRWVAKEQKRMDDSFEWLRQRRAKIEAQNHELKLKNEKESLGESIADICVKPGEVDWLYGPQEVYDDLTTSNDAIDKSTLDEELDRPNSIFQIYTQNPEIPELVPSESFSSPKRILIQEVTTDVEETITLEPSCQNKMANKTAPIKAFLNESTNETREKNLEKIENLAAQAGSTCKNPFENDFLEIDSLE
Sbjct: 1 LICLTSNLPRKLGYDFFVLSYIVNKMNCNCDNFDCSMEDLKLISETTPISSVEEIDFKQENCVLDQKLDEIECENDMPSEYNFNSTNNNECDENEELIDENFNHNLNLKICDDETFNTCINAIEDPLKSSMCLDLSILTNISDDMEDEKIIQHPFNDISNINKEEKEQRKREIDAEIEKHKWPRMTTDYLKKHCKENKLYITPRLNDILYLHYKGFAFIENLDEYVGLRCLFLETNGISKIENLEMLTELRCLYLSKNLISRIENIATLVNLDSIDLSHNLVAKIENLRNLPKFTKLILAHNKVQKISDLEELIYCDNISVLDLQHNQIDDPNVIEEIFAKMKSLRVLYLQGNQFMKNVKNYRKHVINLCKNLTYLDERPVFEKDRACAEAFCRGGIEEEKDERNRWVAKEQKRMDDSFEWLRQRRAKIEAQNHELKLKNEKESLGESIADICVKPGEVDWLYGPQEVYDDLTTSNDAIDKSTLDEELDRPNSIFQIYTQNPEIPELVPSESFSSPKRILIQEVTTDVEETITLEPSCQNKMANKTAPIKAFLNESTNETREKNLEKIENLAAQAGSTCKNPFENDFLEIDSLE 594
BLAST of LRRC50 vs. TrEMBL
Match: A0A3R7ET94 (Dynein assembly factor 1, axonemal homolog (Fragment) OS=Clonorchis sinensis OX=79923 GN=DNAAF1 PE=3 SV=1) HSP 1 Score: 367.851 bits (943), Expect = 3.303e-115 Identity = 190/395 (48.10%), Postives = 270/395 (68.35%), Query Frame = 3
Query: 492 EEKEQRKREIDAEIEKHKWPRMTTDYLKKHCKENKLYITPRLNDILYLHYKGFAFIENLDEYVGLRCLFLETNGISKIENLEMLTELRCLYLSKNLISRIENIATLVNLDSIDLSHNLVAKIENLRNLPKFTKLILAHNKVQKISDLEELIYCDNISVLDLQHNQIDDPNVIEEIFAKMKSLRVLYLQGNQFMKNVKNYRKHVINLCKNLTYLDERPVFEKDRACAEAFCRGGIEEEKDERNRWVAKEQKRMDDSFEWLRQRRAKIEAQNHELKLKNEKESLGESIADICVKPGEVDWLYGP--QEVYDDLTTSNDAIDKSTLDEELDRP--NSIFQIYTQNPEIPELVPSESFSSP--KRILIQEVTTDVEETITLEPSCQNKMANKTAPIKAF 1658
E K+ R + + E+ ++K PRMT ++LK+HC +NKLY TP LND+LYLHY GF+ IENL+EY GLRCLFLE NG+ + LE ELR LY++KNL+ +IEN+ + LD++D+S+N+++KIENL LP FT+LI+AHNK+ + DL +I C +SVLDLQHN I DP V+EE+FAKM SLRVLY QGN F++ VKNYRK VINLCK LTYLD+RPVF KDRACAEAF GG E E + R +W A+EQ+++ DS +WLR++R IEA+ E +L+ E+ G +I V PG++DWLYG Q+V ++ ++ D ++ EE+ P N+ I + ++ EL ++ S P +I+EV ++ E + +N ++ + ++AF
Sbjct: 135 EPKQDRAPQREEEL-RYKGPRMTKEFLKRHCAKNKLYQTPHLNDVLYLHYNGFSKIENLEEYTGLRCLFLEVNGLDSLAGLEQQKELRSLYVAKNLLRKIENLDHMQYLDTLDVSNNMISKIENLDMLPNFTRLIIAHNKLTTLEDLLHVINCPQLSVLDLQHNHIKDPKVVEEVFAKMPSLRVLYNQGNPFVRVVKNYRKKVINLCKQLTYLDDRPVFPKDRACAEAFYEGGAELENEVRQKWNAEEQQKIIDSCQWLREKRQIIEARRREKELREAAEAAGLPTDNIHVNPGDIDWLYGANQQDVSEEAESNGDE-EQGDKTEEVSEPEQNNSENITSGAGDMGELQRTQPRSGPIMAAHMIKEVCDELHEICKGTSTLRNSVSREEEELQAF 527
BLAST of LRRC50 vs. TrEMBL
Match: A0A4S2LUC9 (Dynein assembly factor 1, axonemal homolog OS=Opisthorchis felineus OX=147828 GN=CRM22_004809 PE=3 SV=1) HSP 1 Score: 373.244 bits (957), Expect = 5.761e-115 Identity = 190/397 (47.86%), Postives = 267/397 (67.25%), Query Frame = 3
Query: 483 INKEEKEQRKREIDAEIEKHKWPRMTTDYLKKHCKENKLYITPRLNDILYLHYKGFAFIENLDEYVGLRCLFLETNGISKIENLEMLTELRCLYLSKNLISRIENIATLVNLDSIDLSHNLVAKIENLRNLPKFTKLILAHNKVQKISDLEELIYCDNISVLDLQHNQIDDPNVIEEIFAKMKSLRVLYLQGNQFMKNVKNYRKHVINLCKNLTYLDERPVFEKDRACAEAFCRGGIEEEKDERNRWVAKEQKRMDDSFEWLRQRRAKIEAQNHELKLKNEKESLGESIADICVKPGEVDWLYGP-QEVYDDLTTSNDAIDKSTLDEELDRP--NSIFQIYTQNPEIPELVPSESFSSP--KRILIQEVTTDVEETITLEPSCQNKMANKTAPIKAF 1658
+++ E +Q + E ++K PRMT ++LKKHC +NKLY TP LND+LYLHY GF+ IENL+EY GLRCLFLE NG+ + LE ELR LYL+KNL+ RIEN+ + LD++D+S+N+++KIENL LP FT+LI+AHNK+ + DL +I C +SVLDLQHN I DP V+EE+FAKM SLRVLY QGN F++ VKNYRK VINLCK LTYLD+RPVF KDRACAEAF GG E E + R +W A+EQ+++ DS WLR++R IEA+ E +L+ E+ G +I V PG++DWLYG Q+ ++ SN ++ EE+ P ++ ++ + ++ E ++ S P LI+EV ++ E + +N ++ + ++AF
Sbjct: 118 VSRHEPKQDRAPQQEEESRYKGPRMTKEFLKKHCAKNKLYQTPHLNDVLYLHYNGFSKIENLEEYTGLRCLFLEVNGLDSLTGLEQQKELRSLYLAKNLLRRIENLDHMQYLDTLDVSNNMISKIENLDMLPNFTRLIIAHNKLTTLEDLLHVIKCPQLSVLDLQHNHIKDPEVVEEVFAKMPSLRVLYNQGNPFVRVVKNYRKKVINLCKQLTYLDDRPVFPKDRACAEAFFEGGAELENEVRQKWNAEEQQKIIDSCRWLREKRQIIEARRREKELREAAEAAGLPTDNIHVNPGDIDWLYGANQQDVNEGAHSNGDEEQGDRTEEVSEPEQSNSEKVTSGAGDMGEFQRTQPRSGPIMAAQLIEEVCDELHEICKGTSTLRNSVSKEEEELRAF 514
BLAST of LRRC50 vs. TrEMBL
Match: A0A504YDX5 (Dynein assembly factor 1, axonemal homolog OS=Fasciola gigantica OX=46835 GN=FGIG_08403 PE=3 SV=1) HSP 1 Score: 362.459 bits (929), Expect = 1.021e-111 Identity = 190/361 (52.63%), Postives = 252/361 (69.81%), Query Frame = 3
Query: 399 LDLSILTNISDDMEDEKIIQHPFN----DISNINKEEKEQRKREIDAEIEKHKWPRMTTDYLKKHCKENKLYITPRLNDILYLHYKGFAFIENLDEYVGLRCLFLETNGISKIENLEMLTELRCLYLSKNLISRIENIATLVNLDSIDLSHNLVAKIENLRNLPKFTKLILAHNKVQKISDLEELIYCDNISVLDLQHNQIDDPNVIEEIFAKMKSLRVLYLQGNQFMKNVKNYRKHVINLCKNLTYLDERPVFEKDRACAEAFCRGGIEEEKDERNRWVAKEQKRMDDSFEWLRQRRAKIEAQNHELKLKNEKESLGESIADICVKPGEVDWLYG----PQEVYDDLTTSNDAIDKSTLD 1457
LD S+LT+ D K + +P S + KEE+++R E +AE + PRMT ++L+KHC ++KLY TP+LNDILYLH+ GF+ IENL+EY GLRCLFLE NGI +I LE E+R LYL+KNLI RIEN+ + +LD++D+S+N++AKIENL LPKFT+L++AHNK+ ++ DL L+ C +SVLD+QHNQI D NV+EE+FAKM SLRVLY QGN F++ V+NYRK +IN CKNLTYLD+RPVF KDRACAEAF GG E E R W EQ+++ DS WL ++R IEA+ E +L+ + E+ G S +I V PG+VDWLYG PQ +L + + ST D
Sbjct: 110 LDFSLLTS------DLKNLPYPPGYSILKRSEVLKEERQRRSTEQEAE---SRLPRMTKEFLRKHCAKHKLYQTPQLNDILYLHFNGFSKIENLEEYTGLRCLFLEVNGIDRIGGLEQQKEMRSLYLAKNLIRRIENLDHMQHLDTLDVSNNMIAKIENLDMLPKFTRLVIAHNKLSELDDLIHLVNCKQLSVLDIQHNQIKDANVVEEVFAKMPSLRVLYNQGNPFVREVRNYRKSIINQCKNLTYLDDRPVFPKDRACAEAFFIGGAEHESAVRQEWNNAEQQKLLDSCRWLTEKRKLIEARRRERELREQAEAAGLSAENIHVNPGDVDWLYGDVKPPQAPAGELGEQKEVQESSTHD 461
BLAST of LRRC50 vs. TrEMBL
Match: A0A4Z2CWE1 (Dynein assembly factor 1, axonemal homolog OS=Schistosoma japonicum OX=6182 GN=EWB00_006926 PE=3 SV=1) HSP 1 Score: 352.058 bits (902), Expect = 9.004e-110 Identity = 182/352 (51.70%), Postives = 241/352 (68.47%), Query Frame = 3
Query: 360 INAIEDPLKSSMCLDLSILTNISDDMEDEKIIQHP-------FNDISNINKEEKEQRKREIDAEIEKHKWPRMTTDYLKKHCKENKLYITPRLNDILYLHYKGFAFIENLDEYVGLRCLFLETNGISKIENLEMLTELRCLYLSKNLISRIENIATLVNLDSIDLSHNLVAKIENLRNLPKFTKLILAHNKVQKISDLEELIYCDNISVLDLQHNQIDDPNVIEEIFAKMKSLRVLYLQGNQFMKNVKNYRKHVINLCKNLTYLDERPVFEKDRACAEAFCRGGIEEEKDERNRWVAKEQKRMDDSFEWLRQRRAKIEAQNHELKLKNEKESLGESIADICVKPGEVDWLYG 1394
+N D +K SM LSI D + +P ND++ I + Q K + E E K PRMT +LK+HC +NKLY TP LND+LYLHY GF+ IENLDEY L+CLFL+ NGI KI+ L ELR LYLSKNL+ IEN+ + LD++D+S+N++++I+NL LP FTKLI++HNK+ +I DL LI C+ +SVLD+QHN I DPNV+EEIFAKM +LRVLY QGN F++ VKNYRK+VIN CK LTYLD+RPVF KDRACAEAF GIE+E++ R +W EQK++ DS + L + R +IEA++ E +L+ + + G DI + PG++DWLYG
Sbjct: 16 VNKSNDDIKKSMIDSLSI---------DLSNLPYPPGYSITKLNDVTVI---SQNQMKTLNETEQENTKEPRMTKAFLKQHCTKNKLYQTPHLNDVLYLHYNGFSKIENLDEYTNLKCLFLDVNGILKIDGLHNQHELRSLYLSKNLLRHIENLNHMKYLDTLDVSYNMISRIDNLNMLPNFTKLIISHNKLTEIDDLIHLIKCEKLSVLDIQHNSIKDPNVVEEIFAKMLNLRVLYNQGNPFIREVKNYRKNVINQCKQLTYLDDRPVFPKDRACAEAFYAEGIEKEREVRQQWNDAEQKKILDSVKCLSKTRKRIEAEHREKELRKQAKEAGLPTDDIHIAPGDIDWLYG 355
BLAST of LRRC50 vs. Ensembl Cavefish
Match: dnaaf1 (dynein axonemal assembly factor 1 [Source:NCBI gene;Acc:103025595]) HSP 1 Score: 273.478 bits (698), Expect = 1.557e-83 Identity = 149/343 (43.44%), Postives = 216/343 (62.97%), Query Frame = 3
Query: 477 SNINKEEKEQRKREIDAEIEKHKWPRMTTDYLKKHCKENKLYITPRLNDILYLHYKGFAFIENLDEYVGLRCLFLETNGISKIENLEMLTELRCLYLSKNLISRIENIATLVNLDSIDLSHNLVAKIENLRNLPKFTKLILAHNKVQKISDLEELIYCDNISVLDLQHNQIDDPNVIEEIFAKMKSLRVLYLQGNQFMKNVKNYRKHVINLCKNLTYLDERPVFEKDRACAEAFCRGGIEEEKDERNRWVAKEQKRMDDSFEWL--------RQRRAKIEAQNHELKLKNEKESLGESIADICVKPGEVDWLYGPQEVYDDLTTSNDAIDKSTLDEELDRPNS 1481
+NI++E EQ + I PR+T +L+ HC++NKLY+TPRLND LYLHYKGF IE L+EY GLR L+L+ NGI KIENL+ TELRCLYL +NLI +EN+ L L ++++S+N + I+NL L + T L ++HN ++ DL EL C +ISVLDL HN++ DP ++ I +M LRVLYL GN+ +K + NYRK +I K LTYLD+RPVF ++RACAEA+ GG++ E+ ER W ++E++R+ DS + + +QRRA+ Q E + + GE +A + G+ + + P +Y D S ++ + EE+D NS
Sbjct: 31 TNISEEVSEQAAPDTSRNI---SGPRITKKFLRDHCEQNKLYLTPRLNDTLYLHYKGFMVIEGLEEYTGLRSLWLQCNGIKKIENLQNQTELRCLYLHQNLIHTLENLHPLTMLSTLNVSNNRIRVIQNLACLSQLTTLQISHNALETAQDLMELRLCPSISVLDLSHNRLSDPQIV-SILEQMPDLRVLYLVGNEVIKKIPNYRKSLIIRLKQLTYLDDRPVFPRERACAEAWLVGGLDGERRERELWQSRERRRIQDSLDAMAAIRENAIKQRRAR--EQQEEKGIPESQNLTGEDLARPEKELGQSELILEPV-IYPD---SGLVLEVQSESEEIDTTNS 363
BLAST of LRRC50 vs. Ensembl Cavefish
Match: ppp1r7 (protein phosphatase 1 regulatory subunit 7 [Source:NCBI gene;Acc:111191999]) HSP 1 Score: 77.7962 bits (190), Expect = 3.623e-15 Identity = 60/159 (37.74%), Postives = 88/159 (55.35%), Query Frame = 3
Query: 597 LYITPRLNDILYLHYKGFAFIENLDEYVGLRCLFLETNGISKIENLEMLTELRCLYLSKNLISRIENIATLVNLDSIDLSHNLVAKIENLRNLPKFTKLILAHNKVQKISDLEELIYCDNISVLDLQHNQIDDPNVIEEIFAKMKSLRVLYLQGNQFMK 1073
+ + P D+ +H + IE L+ + L L N I KIENLE L+ LR L L N I ++EN+ L L+ +D+S NL+ KIE L L K KL L HNK+ I++LE L ++ +L+L N+I +IE + A + SL L+L N+ K
Sbjct: 58 ITLDPNEEDVDLVHCR-IGKIEGLEVLQKAKTLSLRQNLIKKIENLESLSSLRELDLYDNQIRKLENLQALTELEQLDVSFNLLRKIEGLERLTKVKKLFLLHNKISSIANLEHLT---SLHMLELGSNRI---RIIENLDA-LTSLDSLFLGTNKITK 208 HSP 2 Score: 77.7962 bits (190), Expect = 3.690e-15 Identity = 56/162 (34.57%), Postives = 88/162 (54.32%), Query Frame = 3
Query: 624 ILYLHYKGFAFIENLDEYVGLRCLFLETNGISKIENLEMLTELRCLYLSKNLISRIENIATLVNLDSIDLSHNLVAKIENLRNLPKFTKLILAHNKVQKISDLEELIYCDNISVLDLQHNQIDDPNVIEEIFAKMKSLRVLYLQGNQFMKNVKNYRKHVINL 1109
+L L IENLD L LFL TN I+K++NL+ L L L + N I+++E + +VNL + LSHN + IE L N K T L +A N+++KI ++ L + D NQI++ + ++E+ K L +YL+ N K+ + RK ++ L
Sbjct: 176 MLELGSNRIRIIENLDALTSLDSLFLGTNKITKLQNLDGLHNLTVLSIQSNRITKLEGLQNMVNLRELYLSHNGIEVIEGLENNKKLTTLDIAANRIKKIENISHLTDLQEFWMND---NQIENWSDLDEL-KNAKGLETVYLERNPLQKDPQYRRKIMLAL 333 HSP 3 Score: 66.6254 bits (161), Expect = 2.065e-11 Identity = 44/112 (39.29%), Postives = 62/112 (55.36%), Query Frame = 3
Query: 657 IENLDEYVGLRCLFLETNGISKIENLEMLTELRCLYLSKNLISRIENIATLVNLDSIDLSHNLVAKIENLRNLPKFTKLILAHNKVQKISDLEELIYCDNISVLDLQHNQID 992
IE L+ ++ LFL N IS I NLE LT L L L N I IEN+ L +LDS+ L N + K++NL L T L + N++ K+ L+ ++ N+ L L HN I+
Sbjct: 143 IEGLERLTKVKKLFLLHNKISSIANLEHLTSLHMLELGSNRIRIIENLDALTSLDSLFLGTNKITKLQNLDGLHNLTVLSIQSNRITKLEGLQNMV---NLRELYLSHNGIE 251 HSP 4 Score: 64.3142 bits (155), Expect = 9.887e-11 Identity = 52/148 (35.14%), Postives = 79/148 (53.38%), Query Frame = 3
Query: 657 IENLDEYVGLRCLFLETNGISKIENLEMLTELRCLYLSKNLISRIENIATLVNLDSIDLSHNLVAKIENLRNLPKFTKLILAHNKVQKISDLEELIYCDNISVLDLQHNQIDDPNVIEEIFAKMKSLRVLYLQ--GNQFMKNVKNYRK 1094
+ENL L L + N + KIE LE LT+++ L+L N IS I N+ L +L ++L N + IENL L L L NK+ K+ +L+ L N++VL +Q N+I E M +LR LYL G + ++ ++N +K
Sbjct: 121 LENLQALTELEQLDVSFNLLRKIEGLERLTKVKKLFLLHNKISSIANLEHLTSLHMLELGSNRIRIIENLDALTSLDSLFLGTNKITKLQNLDGL---HNLTVLSIQSNRITKL----EGLQNMVNLRELYLSHNGIEVIEGLENNKK 261
BLAST of LRRC50 vs. Ensembl Cavefish
Match: lrrcc1 (leucine rich repeat and coiled-coil centrosomal protein 1 [Source:ZFIN;Acc:ZDB-GENE-041111-207]) HSP 1 Score: 67.3958 bits (163), Expect = 3.120e-11 Identity = 48/152 (31.58%), Postives = 82/152 (53.95%), Query Frame = 3
Query: 699 LETNGISKIENLEMLTELRCLYLSKNLISRIENIATLVNLDSIDLSHNLVAKIENLRNLPKFTKLILAHNKVQKISDLEELIYCDN----ISVLDLQHNQIDDPNVIEEIFAKMKSLRVLYLQGNQF---MKNVKNYRKHVINLCKNLTYLD 1133
L N +SKIE L +R L LS N ISRIE + L +L +++LS N + K+E L L T+L L++N +I+DL L+Y + L L N +D+ N + + +++LR + L+ + + ++ YR+ V+ + ++ LD
Sbjct: 30 LHCNRLSKIEGLTTAWHIRHLDLSSNHISRIEGLGALTSLRTLNLSCNSITKVEGLNGLTNVTRLNLSYN---QINDLTGLLYLHGTEYKLKHLQLHGNHLDNINHLLQCMVGLRNLRDMTLRRDGVDNPVCSLPGYREMVLQSLQQISTLD 178
BLAST of LRRC50 vs. Ensembl Cavefish
Match: drc3 (dynein regulatory complex subunit 3 [Source:ZFIN;Acc:ZDB-GENE-061103-349]) HSP 1 Score: 62.7734 bits (151), Expect = 4.916e-10 Identity = 60/181 (33.15%), Postives = 80/181 (44.20%), Query Frame = 3
Query: 627 LYLHYKGFAFIENLDEYVGLRCLFLETNGISKIENLEMLTELRCLYLSKNLISRIENIATLVNLDSIDLSHNLVAKIENLRNLPKFTKLILAHNKVQKISDLEELIYCDNISVLDLQHNQIDDPNVIEEIFAKMKSLRVLYLQGNQFMKNVKNYRKHVINLCKNLTYLDERPVFEKDRACA 1169
L L YK I++L E+ L L L N I KI+ LE LT L L LS N I IE + LV L ++ LS+N + IE + L L L N + +I DN+ L + K+LR L L N + NY+ V+ +L YLD R V E+ R A
Sbjct: 48 LRLEYKKILQIDHLWEFTSLTKLQLNNNSIEKIQGLEKLTNLLWLDLSFNKIKMIEGLEALVKLQTLSLSNNQIPAIEKMDTLEHLEILSLGENVISQI---------DNVIYL-----------------RRFKNLRSLNLARNPICQET-NYKIFVVAYLPDLVYLDFRLVDEQTRERA 201
BLAST of LRRC50 vs. Ensembl Cavefish
Match: ENSAMXT00000057771.1 (pep primary_assembly:Astyanax_mexicanus-2.0:24:38132889:38135255:-1 gene:ENSAMXG00000029033.1 transcript:ENSAMXT00000057771.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 57.7658 bits (138), Expect = 4.961e-9 Identity = 49/149 (32.89%), Postives = 68/149 (45.64%), Query Frame = 3
Query: 711 GISKIENLEMLTELRCLYLSKNLISRIENIATLVNLDSIDLSHNLVAKIENLRNLPKFTKLILAHNKVQKISDLEELIYCDNISVLDLQHNQIDDPNVIEEIFAKMKSLRVLYLQGNQFMKNVKNYRKHVINLCKNLTYLDERPVFEKD 1157
ISKIE LE+LT L CL LS N I IE + TLV L ++LS N ++ IEN+ L L LAH ++ C Q+D+ E + K+LR L L GN + NY +++ +T E+D
Sbjct: 17 SISKIEGLEILTNLECLDLSYNKIKVIEGLDTLVKLKQLNLSMNNISVIENMDTLEHLQHLSLAHTRI-----------C-----------QLDNT---VEYLRRFKNLRSLRLAGNPISRKT-NYTLYIVRALDEITVTGSLSELEED 139 HSP 2 Score: 49.2914 bits (116), Expect = 2.926e-6 Identity = 35/98 (35.71%), Postives = 51/98 (52.04%), Query Frame = 3
Query: 639 YKGFAFIENLDEYVGLRCLFLETNGISKIENLEMLTELRCLYLSKNLISRIENIATLVNLDSIDLSHNLVAKIEN----LRNLPKFTKLILAHNKVQK 920
+ + IE L+ L CL L N I IE L+ L +L+ L LS N IS IEN+ TL +L + L+H + +++N LR L LA N + +
Sbjct: 15 FVSISKIEGLEILTNLECLDLSYNKIKVIEGLDTLVKLKQLNLSMNNISVIENMDTLEHLQHLSLAHTRICQLDNTVEYLRRFKNLRSLRLAGNPISR 112
BLAST of LRRC50 vs. Ensembl Sea Lamprey
Match: ppp1r7 (protein phosphatase 1, regulatory (inhibitor) subunit 7 [Source:NCBI gene;Acc:560323]) HSP 1 Score: 79.7221 bits (195), Expect = 1.922e-16 Identity = 52/124 (41.94%), Postives = 73/124 (58.87%), Query Frame = 3
Query: 621 DILYLHYKGFAFIENLDEYVGLRCLFLETNGISKIENLEMLTELRCLYLSKNLISRIENIATLVNLDSIDLSHNLVAKIENLRNLPKFTKLILAHNKVQKISDLEELIYCDNISVLDLQHNQID 992
++L + + IE LD +R LFL +N I+KIENL LTELR L ++ N I IENI TL NLDS+ + N + K++NL +L T L + N++ KI L L+ N+ L L HN I+
Sbjct: 125 EMLDISFNVLRKIEGLDTLRKVRKLFLVSNKITKIENLNSLTELRMLEVASNRIRVIENIETLKNLDSLFIGKNKITKLQNLDSLTNLTVLSIQSNRITKIEGLSSLV---NLQELYLSHNGIE 245 HSP 2 Score: 77.0258 bits (188), Expect = 1.455e-15 Identity = 58/147 (39.46%), Postives = 87/147 (59.18%), Query Frame = 3
Query: 633 LHYKGFAFIENLDEYVGLRCLFLETNGISKIENLEMLTELRCLYLSKNLISRIENIATLVNLDSIDLSHNLVAKIENLRNLPKFTKLILAHNKVQKISDLEELIYCDNISVLDLQHNQIDDPNVIEEIFAKMKSLRVLYLQGNQFMK 1073
L++ IE L+ + ++ L L N I++IENLE LT LR L L N++ +IEN+ TLVNL+ +D+S N++ KIE L L K KL L NK+ KI +L L + +L++ N+I VIE I +K+L L++ N+ K
Sbjct: 63 LNHCRIGKIERLEILMKVKVLCLRQNMIAQIENLESLTTLRELDLYDNVLKKIENLDTLVNLEMLDISFNVLRKIEGLDTLRKVRKLFLVSNKITKIENLNSL---TELRMLEVASNRI---RVIENI-ETLKNLDSLFIGKNKITK 202 HSP 3 Score: 75.0998 bits (183), Expect = 6.387e-15 Identity = 52/152 (34.21%), Postives = 87/152 (57.24%), Query Frame = 3
Query: 654 FIENLDEYVGLRCLFLETNGISKIENLEMLTELRCLYLSKNLISRIENIATLVNLDSIDLSHNLVAKIENLRNLPKFTKLILAHNKVQKISDLEELIYCDNISVLDLQHNQIDDPNVIEEIFAKMKSLRVLYLQGNQFMKNVKNYRKHVINL 1109
IEN++ L LF+ N I+K++NL+ LT L L + N I++IE +++LVNL + LSHN + IE L N K T L +A N+V++I ++ L + D NQI + N ++E+ + L+ +YL+ N ++ + RK ++ L
Sbjct: 180 VIENIETLKNLDSLFIGKNKITKLQNLDSLTNLTVLSIQSNRITKIEGLSSLVNLQELYLSHNGIEVIEGLENNKKLTTLDIAANRVRRIENVGHLTELQEFWMND---NQISNWNDVDEL-KNARGLQTVYLERNPLQRDPQYRRKIMLAL 327 HSP 4 Score: 59.6918 bits (143), Expect = 5.955e-10 Identity = 58/183 (31.69%), Postives = 89/183 (48.63%), Query Frame = 3
Query: 579 HCKENK---LYITPRLNDILYLHYKGFAFIENLDEYVGLRCLFLETNGISKIENLEMLTELRCLYLSKNLISRIENIATLVNLDSIDLSHNLVAKIENLRNLPKFTKLILAHNKVQ-------------------KISDLEELIYCDNISVLDLQHNQIDDPNVIEEIFAKMKSLRVLYLQGN 1061
HC+ K L I ++ +L L A IENL+ LR L L N + KIENL+ L L L +S N++ +IE + TL + + L N + KIENL +L + L +A N+++ KI+ L+ L N++VL +Q N+I E + + +L+ LYL N
Sbjct: 65 HCRIGKIERLEILMKV-KVLCLRQNMIAQIENLESLTTLRELDLYDNVLKKIENLDTLVNLEMLDISFNVLRKIEGLDTLRKVRKLFLVSNKITKIENLNSLTELRMLEVASNRIRVIENIETLKNLDSLFIGKNKITKLQNLDSLTNLTVLSIQSNRITKI----EGLSSLVNLQELYLSHN 242 HSP 5 Score: 58.9214 bits (141), Expect = 1.010e-9 Identity = 41/141 (29.08%), Postives = 73/141 (51.77%), Query Frame = 3
Query: 621 DILYLHYKGFAFIENLDEYVGLRCLFLETNGISKIENLEMLTELRCLYLSKNLISRIENIATLVNLDSIDLSHNLVAKIENLRNLPKFTKLILAHNKVQKISDLEELIYCDNISVLDLQHNQID-DPNVIEEIFAKMKSLR 1040
D L++ ++NLD L L +++N I+KIE L L L+ LYLS N I IE + L ++D++ N V +IEN+ +L + + + N++ +D++EL + + L+ N + DP +I + +R
Sbjct: 191 DSLFIGKNKITKLQNLDSLTNLTVLSIQSNRITKIEGLSSLVNLQELYLSHNGIEVIEGLENNKKLTTLDIAANRVRRIENVGHLTELQEFWMNDNQISNWNDVDELKNARGLQTVYLERNPLQRDPQYRRKIMLALPWVR 331
BLAST of LRRC50 vs. Ensembl Sea Lamprey
Match: LRRC49 (leucine rich repeat containing 49 [Source:HGNC Symbol;Acc:HGNC:25965]) HSP 1 Score: 61.2326 bits (147), Expect = 3.962e-10 Identity = 46/122 (37.70%), Postives = 66/122 (54.10%), Query Frame = 3
Query: 699 LETNGISKIENLEMLTELRCLYLSKNLISRIENIATLVNLDSIDLSHNLVAKIENLRNLPKFTKLILAHNKVQKISDLEELIYCDNISVLDLQHNQIDDPNVIEEIFAKMKSLRVLYLQGNQ 1064
L++ G++ L+ +LR L L NLI R ++++ L L +DL N + +I L NL L+L N+++KI+ LE L D VLDL NQI V E + + LRVL L GNQ
Sbjct: 37 LDSRGMTMCPILDGEEDLRLLSLQHNLIRRAQHLSHLRRLVFLDLYANELEEISGLYNLRSLRVLMLGKNRIRKITSLESLTKLD---VLDLHGNQI----VRIENLSHLSELRVLNLAGNQ 151 HSP 2 Score: 58.151 bits (139), Expect = 4.306e-9 Identity = 57/211 (27.01%), Postives = 99/211 (46.92%), Query Frame = 3
Query: 687 RCLFLE--TNGISKIENLEMLTELRCLYLSKNLISRIENIATLVNLDSIDLSHNLVAKIENLRNLPKFTKLILAHNKVQKISDLEELIYCDNISVLDLQHNQIDD-------PNVIEEIF---------------AKMKSLRVLYLQGNQFMKNVKNYRKHVINLCKNLTYLDERPVFEKDRACAEAFCRGGIEEEKDERNRWVAKEQKRM 1247
R +FL+ N + +I L L LR L L KN I +I ++ +L LD +DL N + +IENL +L + L LA N++ + L L +++ L+L+ N I P+ ++ +F + SL + L GN + YR+ + L LD + V E++R A R E++++ + + KE++R+
Sbjct: 75 RLVFLDLYANELEEISGLYNLRSLRVLMLGKNRIRKITSLESLTKLDVLDLHGNQIVRIENLSHLSELRVLNLAGNQITHVDSLRGL---HSLAELNLRRNNISSMKEVDCLPS-LQRLFLSYNNIANFDGIVCLREAPSLCEVALDGNPLAQEA-CYRQTALRHMGQLRQLDMKRVTEEERRLASLLARKQEEKKREFHKQAIQKEKRRL 280
BLAST of LRRC50 vs. Ensembl Sea Lamprey
Match: lrguk (leucine-rich repeats and guanylate kinase domain containing [Source:ZFIN;Acc:ZDB-GENE-050419-232]) HSP 1 Score: 54.6842 bits (130), Expect = 3.907e-8 Identity = 45/156 (28.85%), Postives = 79/156 (50.64%), Query Frame = 3
Query: 618 NDILYLHYK--GFAF--IENLDEYVGLRCLFLETNGISKIENLEMLTELRCLYLSKNLISRIENIATLVNLDSIDLSHNLVAKIENLRNLPKFTKLILAHNKVQKISDLEELIYCDNISVLDLQHNQIDDPNVIEEIFAKMKSLRVLYLQGNQFMK 1073
D++YLH G+ I L YV ++ L L N I ++ L + L L +S N ++++ + L L D S+N +++++++ TKL+L +N + +I LEE C +++ L L HN+I + + + LR L L+GN K
Sbjct: 21 TDLVYLHLALPGYGLKDIGILSGYVHIQKLDLSHNKIKELSVLGNMPYLVELKVSHNQLTKLFEFSILRFLKEADFSYNTISEMKDMSVYKSLTKLVLDNNNISEIIGLEE---CGSLAYLSLAHNRIRRLDGLGSL-----PLRYLCLRGNHLRK 168
BLAST of LRRC50 vs. Ensembl Sea Lamprey
Match: lrrc6 (leucine rich repeat containing 6 [Source:NCBI gene;Acc:432388]) HSP 1 Score: 52.373 bits (124), Expect = 1.849e-7 Identity = 61/213 (28.64%), Postives = 91/213 (42.72%), Query Frame = 3
Query: 663 NLDEYVGLRCLFLETNGISKIENLEML-TELRCLYLSKNLISRIENIATLVNLDSIDLSHNLVAKIENLRNLPKFTKLILAHNKVQKISDLEELIYCDNISVLDLQHNQIDDPNVIEEIFAKMKSLRVLYLQGNQFMKNVKNYRKHVINLCKNLTYLDERPVFEKDRACAEAFCRGGIEEEKDERNRWVAKEQKRMDDSFEWLRQRRAKIEAQ 1298
N E L L L I ++++L++ L+ LYL N+I RIEN++ L L+ I+L+ N V +IENL+ KL L N V ++S +E L+HN + +EE+F L GN + + YR +V+ L LD G E E+ ER R EW R+R + EA+
Sbjct: 13 NNGELFSLEELSLHQQQIERLQHLDVWCRHLKTLYLHNNVIPRIENLSRLKELEYINLALNNVERIENLQGCESLQKLDLTVNFVGELSSVE-----------TLRHNPL-----LEELF----------LVGNP-CADFEGYRPYVVATLPQLKRLD------------------GQEIERSER--------IRAHQELEWTRRRVLEQEAE 172
BLAST of LRRC50 vs. Ensembl Sea Lamprey
Match: ppp1r42 (protein phosphatase 1, regulatory subunit 42 [Source:NCBI gene;Acc:431749]) HSP 1 Score: 50.8322 bits (120), Expect = 2.352e-7 Identity = 52/197 (26.40%), Postives = 87/197 (44.16%), Query Frame = 3
Query: 660 ENLDEYVGLRCLFLETNGISKIENLEMLTELRCLYLSKNLISRIENIATLVNLDSIDLSHNLVAKIENLRNLPKFTKLILAHNKVQKISDLEELIY--------CDNISVLD--------------LQH--------NQIDDPNVIEEIFAKMKSLRVLYLQGNQFMKNVKNYRKHVINLCKNLTYLDERPVFEKDR 1160
E+L L L+L N +S++ NL + L LYL N + R+E +ATL +L + L N ++ +E + L + T+L H + Q + E+L++ ++ VL+ L H NQ+ D + ++ + L L GN F + K YR VI + +L LD + + E R
Sbjct: 1 EDLSACRNLAVLYLYDNRLSRMPNLAFASHLTHLYLQNNALERMEGLATLRHLSKLYLGGNSISVVEGVEMLSELTEL---HLENQHLPPGEKLLFDPRCLSTLAGSLCVLNVSGNGLEELQELTCLSHMMQFMACENQLTDLQDLADVLTCWPKVWRLELLGNPFCQKPK-YRDRVIMMSASLDILDGKEIKESAR 193
BLAST of LRRC50 vs. Ensembl Yeast
Match: SDS22 (Regulatory subunit of the type 1 protein phosphatase (PP1) Glc7p; whether it functions as a positive or negative regulator of Glc7p is controversial; involved in the regulation of Glc7p nuclear localization and function [Source:SGD;Acc:S000001676]) HSP 1 Score: 53.1434 bits (126), Expect = 4.807e-8 Identity = 38/111 (34.23%), Postives = 63/111 (56.76%), Query Frame = 3
Query: 663 NLDEYVGLRCLFLETNGISKIENLEMLTELRCLYLSKNLISRIENIATLVNLDSIDLSHNLVAKIE--NLRNLPKFTKLILAHNKVQKISDLEELIYCDNISVLDLQHNQI 989
N+++ L L L N I I+NLE LT+L LY +N IS+IEN++TL +L +++L N V IE + L ++ L N + ++ +L L N+ +L +Q N++
Sbjct: 108 NVNKLTKLTSLDLSFNKIKHIKNLENLTDLENLYFVQNSISKIENLSTLKSLKNLELGGNKVHSIEPDSFEGLSNLEEIWLGKNSIPRLINLHPL---KNLKILSIQSNKL 215 HSP 2 Score: 52.7582 bits (125), Expect = 7.231e-8 Identity = 57/196 (29.08%), Postives = 89/196 (45.41%), Query Frame = 3
Query: 627 LYLHYKGFAFIENLDEYVGLRCLFLETNGISKIE--NLEMLTELRCLYLSKNLISRIENIATLVNLDSIDL----------------------SHNLVAKIENLRNLPKFTKLILAHNKVQKISDLEELIYCDNISVLDLQHNQIDDP-NVIEEIFAKMKSLRVLYLQGNQF-MKNVKNYRKHV-INLCKNLTYLD 1133
LY + IENL L+ L L N + IE + E L+ L ++L KN I R+ N+ L NL + + SHN + KIE L K T L + N KI+ LE L + N++ + N+ID + E + + L +YL+GN ++N +YR+ + +NL +L +D
Sbjct: 140 LYFVQNSISKIENLSTLKSLKNLELGGNKVHSIEPDSFEGLSNLEEIWLGKNSIPRLINLHPLKNLKILSIQSNKLKKIENLEELTNLEELYLSHNFITKIEGLEKNLKLTTLDVTSN---KITSLENLNHLSNLTDIWASFNKIDQSFESLGENLSALSRLETIYLEGNPIQLENKTSYRRKLTMNLPPSLQKID 332
BLAST of LRRC50 vs. Ensembl Nematostella
Match: EDO32918 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7STQ2]) HSP 1 Score: 249.595 bits (636), Expect = 5.522e-79 Identity = 119/242 (49.17%), Postives = 175/242 (72.31%), Query Frame = 3
Query: 555 MTTDYLKKHCKENKLYITPRLNDILYLHYKGFAFIENLDEYVGLRCLFLETNGISKIENLEMLTELRCLYLSKNLISRIENIATLVNLDSIDLSHNLVAKIENLRNLPKFTKLILAHNKVQKISDLEELIYCDNISVLDLQHNQIDDPNVIEEIFAKMKSL-------RVLYLQGNQFMKNVKNYRKHVINLCKNLTYLDERPVFEKDRACAEAFCRGGIEEEKDERNRWVAKEQKRMDDSF 1259
MT LK+ CK+ KLY+TP LNDILYLH++GF IENL+EY G++CL+LE NGI KIENL + EL+CLYL +N++ ++EN+ L LD++++S+N++ IEN+ LP L +AHN++ D++EL C +S++DL +N+IDDPN++ ++ A+M +L VL L GN +K +KNYRK++I KNL YLD+RPVF ++RAC EA+ +GG EK+ER RW+ KE+++M+D F
Sbjct: 1 MTKKALKQICKDQKLYLTPHLNDILYLHFRGFGKIENLEEYTGVKCLWLECNGIEKIENLGFMKELKCLYLQQNMLKKVENLEELDGLDTLNVSNNIIRSIENIACLPVLNTLQIAHNRLASAGDIKELASCQKLSIVDLSYNKIDDPNIV-DVLAEMPNLVRAHIFGVVLNLIGNPVIKKIKNYRKNMILKLKNLKYLDDRPVFPRERACTEAWAQGGPAAEKEERERWINKERQKMEDGF 241
BLAST of LRRC50 vs. Ensembl Nematostella
Match: EDO38071 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SDZ3]) HSP 1 Score: 75.485 bits (184), Expect = 2.033e-14 Identity = 61/170 (35.88%), Postives = 87/170 (51.18%), Query Frame = 3
Query: 690 CLFLETNGISKIENLEMLTELRCLYLSKNLISRIENIATLVNLDSIDLSHNLVAKIENLRNLPKFTKLILAHNKVQKISDLEELIYCDNISVLDLQHNQIDDPNVIEEIFAKMKSLRVLYLQGNQFMKNVKNYRKHVINLCKNLTYLDERPVFEKDRACAEAFCRGGIEE 1199
L L+ I KI+NL L L L N+I +IE + LVNL +DLS N + IE L L K L L +N++ KI +++ L S+ + Q+D NVI + K+LR L L N F ++ K Y+++VI +L YLD R + E R A + IEE
Sbjct: 47 ALRLDFKNILKIDNLWSFVNLTTLQLDNNIIEKIEGLDMLVNLQWLDLSFNNIEVIEGLDKLTKLKDLTLYNNRITKIENMDSLTNLHVFSIGNNSLKQLD--NVI--YLRRFKNLRTLNLSFNPFCEDSK-YKEYVIAHLPDLVYLDFRLIDETAREAATERYKYSIEE 211
BLAST of LRRC50 vs. Ensembl Nematostella
Match: EDO44937 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RU20]) HSP 1 Score: 70.0922 bits (170), Expect = 3.252e-13 Identity = 58/153 (37.91%), Postives = 83/153 (54.25%), Query Frame = 3
Query: 657 IENLDEYVGLRCLFLETNGISKIENLEMLTELRCLYLSKNLISRIENIATLVNLDSIDLSHNLVAKIENLRNLPKFTKLILAHNKVQKISDLEEL-------IYCDNISVLD-LQH-----NQIDDPNVIEEI--FAKMKSLRVLYLQGNQFM 1070
I+N + ++ L L N I K+ENLE LT L L N IS+IEN+ LVNL +DLS N++ IENL +L K KL L NK+ +I LE L + + I VL+ L+H + N I E+ + + SL+VL +Q N+ +
Sbjct: 42 IQNFERLRCVKSLCLRRNEIKKLENLETLTSLEELDFYDNQISKIENLDRLVNLRILDLSFNVIKVIENLNSLTKLEKLYLVQNKIGRIEGLEHLTELTMVELGANKIRVLEGLEHLTKLESLFVGKNKITELQNLSGLCSLKVLSIQSNRIV 194 HSP 2 Score: 57.7658 bits (138), Expect = 3.935e-9 Identity = 43/149 (28.86%), Postives = 81/149 (54.36%), Query Frame = 3
Query: 654 FIENLDEYVGLRCLFLETNGISKIENLEMLTELRCLYLSKNLISRIENIATLVNLDSIDLSHNLVAKIENLRNLPKFTKLILAHNKVQKISDLEELIYCDNISVLDLQHNQIDDPNVIEEIFAKMKSLRVLYLQGNQFMKNVKNYRKHV 1100
+E L+ L LF+ N I++++NL L L+ L + N I ++ + L +L+ + +SHN + +I+ L +L K L LA N++++IS++ L+ N+ NQ++ ++E+ AK L +YL+ N ++ YR+ V
Sbjct: 151 VLEGLEHLTKLESLFVGKNKITELQNLSGLCSLKVLSIQSNRIVELKGLEHLDSLEELYISHNGIEEIKGLESLTKLNTLDLASNRIKRISNVGHLL---NLEEFWFNDNQLEHWEDLDEL-AKCPKLHTVYLERNPLSRDTA-YRRKV 294 HSP 3 Score: 52.7582 bits (125), Expect = 1.681e-7 Identity = 33/119 (27.73%), Postives = 64/119 (53.78%), Query Frame = 3
Query: 627 LYLHYKGFAFIENLDEYVGLRCLFLETNGISKIENLEMLTELRCLYLSKNLISRIENIATLVNLDSIDLSHNLVAKIENLRNLPKFTKLILAHNKVQKISDLEELIYCDNISVLDLQHN 983
L++ ++NL L+ L +++N I +++ LE L L LY+S N I I+ + +L L+++DL+ N + +I N+ +L + N+++ DL+EL C + + L+ N
Sbjct: 164 LFVGKNKITELQNLSGLCSLKVLSIQSNRIVELKGLEHLDSLEELYISHNGIEEIKGLESLTKLNTLDLASNRIKRISNVGHLLNLEEFWFNDNQLEHWEDLDELAKCPKLHTVYLERN 282
BLAST of LRRC50 vs. Ensembl Nematostella
Match: EDO45771 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RSA0]) HSP 1 Score: 70.0922 bits (170), Expect = 1.394e-12 Identity = 70/225 (31.11%), Postives = 111/225 (49.33%), Query Frame = 3
Query: 657 IENLDEYVGLRCLFLETNGISKIENLEMLTELRCLYLSKNLISRIENIATLVNLDSIDLSHNLVAKIENLRNLPKFTKLILAHNKVQKISDLEELIYCDNISVLDLQHNQIDDPNVIEEI--FAKMKSLRVLYLQGNQFMKNVKNYRKHVINLCKNLTYLDERPVFEKDRACAEAFCRGGIEEEKDERNRWVAKEQKRM---DDSFEW-LRQRRAKIEAQNHELK 1313
I L LR L L N I KI NLE LT+L L L N IS+IEN++ L L ++L+ N + K+ N+ + +L L NK+ + +++ L N+ L L N I E+I + S+ L L GN F +V Y++ V+ L LD + + E++R A R E++K+ V KE++R+ + +W L Q AK +H+++
Sbjct: 86 ISGLSSLKSLRVLMLGKNRIRKINNLEALTKLDVLDLHGNRISKIENLSHLTELRVLNLAGNEILKVCNISGMRSLAELNLRRNKICTVEEVDRL---SNLQRLFLSFNCISR---FEDINCLTRSTSITELSLDGNPFASDV-TYKQTVLKSVTCLRQLDMKRITEEERRIAMVMARKEEEKKKEVNKLAVLKEKRRIAINNAQRQWELTQ--AKTNLGSHQIR 301
BLAST of LRRC50 vs. Ensembl Nematostella
Match: EDO47417 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RLZ8]) HSP 1 Score: 61.2326 bits (147), Expect = 2.019e-10 Identity = 67/225 (29.78%), Postives = 95/225 (42.22%), Query Frame = 3
Query: 627 LYLHYKGFAFIENLDEYVGLRCLFLETNGISKIENLEMLTELRCLYLSKNLISRIENIATLVNLDSIDLSHNLVA------KIENLR-------NLPKFTKLILAHNKVQKIS--------------DLEELIYCDNISVLDLQHNQIDDPNVIEEIFAKMKSLRVLYLQGNQFMKNVKNYRKHVINLCKNLTYLDERPVFEKDRACAEAFCRGGIEEEKDERNR 1220
LYL KG I+NL L L+L N ISKI+NL L LYL N ISRIE + L + L N + K+ENLR +LP KL+ +Q +S ++EL N++ +HN + D + + A L L + GN + K YR +I + +L LD + + A A+ F + KD R R
Sbjct: 34 LYLAEKGIDEIDNLSMCKNLSVLYLYDNNISKIKNLGFAGNLTHLYLQNNKISRIEGLDHCRRLSKLYLGGNSITVIEGLDKLENLRELHMEKQHLPPGEKLLFDPRTLQALSKCLCVLNISENNIDSIDELQCLTNMTQFFTEHNLLADMKELSRVMAAWPYLWRLEVSGNPLCQK-KKYRDRIIVMSNSLVMLDGKEI----NATAKRFLMNW-KANKDARKR 252
BLAST of LRRC50 vs. Ensembl Medaka
Match: dnaaf1 (dynein, axonemal, assembly factor 1 [Source:NCBI gene;Acc:386722]) HSP 1 Score: 197.978 bits (502), Expect = 5.427e-58 Identity = 103/259 (39.77%), Postives = 154/259 (59.46%), Query Frame = 3
Query: 486 NKEEKEQRKREIDAEIEKHKWPRMTTDYLKKHCKENKLYITPRLNDILYLHYKGFAFIENLDEYVGLRCLFLETNGISKIENLEMLTELRCLYLSKNLISRIENIATLVNLDSIDLSHNLVAKIENLRNLPKFTKLILAHNKVQKISDLEELIYCDNISVLDLQHNQIDDPNVIEEIFAKMKSLRVLYLQGNQFMKNVKNYRKHVINLCKNLTYLDERPVFEKDRACAEAFCRGGIEEEKDERNRWVAKEQKRMDDSFE 1262
++EE + +R E WPRMT +L+ CK+NKLY+TP LND LYLH+KGF+ IENL+EY GL+ L+L N + +IENL+ T+LRCL+L+ N I ++EN+ L L ++++S+N ++ +ENL LP+ + L+ DP ++ + M LRVLYL GN+ ++ + NYR+ +I K LT+LD RPVF +DRACAEA+ GG E E+ +W KE+K++ + E
Sbjct: 33 SQEEMKTFQRLSLGGKENSLWPRMTAAFLRDLCKQNKLYMTPHLNDTLYLHFKGFSRIENLEEYTGLKSLWLHNNALERIENLDAQTDLRCLFLNDNQILKLENLQPLTKLCTLNVSNNYISVLENLAYLPRLSTLL-------------------------------HDPEIVC-VLEAMPELRVLYLMGNEVVRKIPNYRRSLIARLKQLTFLDVRPVFPRDRACAEAWAAGGPEAERRVMEQWETKERKKIQKNLE 259
BLAST of LRRC50 vs. Ensembl Medaka
Match: ppp1r7 (protein phosphatase 1 regulatory subunit 7 [Source:NCBI gene;Acc:101158055]) HSP 1 Score: 83.1889 bits (204), Expect = 7.822e-17 Identity = 60/163 (36.81%), Postives = 90/163 (55.21%), Query Frame = 3
Query: 621 DILYLHYKGFAFIENLDEYVGLRCLFLETNGISKIENLEMLTELRCLYLSKNLISRIENIATLVNLDSIDLSHNLVAKIENLRNLPKFTKLILAHNKVQKISDLEELIYCDNISVLDLQHNQIDDPNVIEEIFAKMKSLRVLYLQGNQFMKNVKNYRKHVINL 1109
++L L IENLD L LFL TN I+K++NL+ L L L + N I++IE + LVNL + LSHN + IE L N K T L +A N+V+KI ++ L + D NQI++ + ++E+ KSL +YL+ N K+ + RK ++ L
Sbjct: 175 EMLELGSNRIRVIENLDGLTSLTSLFLGTNKINKLQNLDALHNLSVLSIQSNRITKIEGLQNLVNLKELYLSHNGIEVIEGLENNKKLTTLDIAANRVKKIENISHLTELQEFWMND---NQIENWSDLDEL-KNAKSLETVYLERNPLQKDPQYRRKIMLAL 333 HSP 2 Score: 82.4185 bits (202), Expect = 1.129e-16 Identity = 64/191 (33.51%), Postives = 103/191 (53.93%), Query Frame = 3
Query: 501 EQRKREIDAEIEKHKWPRMTTDYLKKHCKENKLYITPRLNDILYLHYKGFAFIENLDEYVGLRCLFLETNGISKIENLEMLTELRCLYLSKNLISRIENIATLVNLDSIDLSHNLVAKIENLRNLPKFTKLILAHNKVQKISDLEELIYCDNISVLDLQHNQIDDPNVIEEIFAKMKSLRVLYLQGNQFMK 1073
E R++ I+ +++ ++ P TT + + + + P D+ +H + IE L+ + L L N I KIENLE L+ LR L L N I ++EN+ L L+ +D+S N++ KIENL L + KL L HNK+ I++LE + + +L+L N+I VIE + + SL L+L N+ K
Sbjct: 27 ESRRKSINGDVDPNQ-PSTTTSKEESPVDMDTITLDPEEEDVDLVHCR-IGKIEGLEVLQKAKTLSLRQNLIKKIENLESLSSLRELDLYDNQIRKLENLDNLTELEQLDVSFNILRKIENLERLTQLKKLFLVHNKITGIANLEHFSFLE---MLELGSNRI---RVIENLDG-LTSLTSLFLGTNKINK 208 HSP 3 Score: 68.5514 bits (166), Expect = 4.081e-12 Identity = 53/148 (35.81%), Postives = 81/148 (54.73%), Query Frame = 3
Query: 657 IENLDEYVGLRCLFLETNGISKIENLEMLTELRCLYLSKNLISRIENIATLVNLDSIDLSHNLVAKIENLRNLPKFTKLILAHNKVQKISDLEELIYCDNISVLDLQHNQIDDPNVIEEIFAKMKSLRVLYLQ--GNQFMKNVKNYRK 1094
+ENLD L L + N + KIENLE LT+L+ L+L N I+ I N+ L+ ++L N + IENL L T L L NK+ K+ +L+ L N+SVL +Q N+I E + +L+ LYL G + ++ ++N +K
Sbjct: 121 LENLDNLTELEQLDVSFNILRKIENLERLTQLKKLFLVHNKITGIANLEHFSFLEMLELGSNRIRVIENLDGLTSLTSLFLGTNKINKLQNLDAL---HNLSVLSIQSNRITKI----EGLQNLVNLKELYLSHNGIEVIEGLENNKK 261
BLAST of LRRC50 vs. Ensembl Medaka
Match: ppp1r7 (protein phosphatase 1 regulatory subunit 7 [Source:NCBI gene;Acc:101158055]) HSP 1 Score: 79.7221 bits (195), Expect = 1.345e-15 Identity = 60/163 (36.81%), Postives = 90/163 (55.21%), Query Frame = 3
Query: 621 DILYLHYKGFAFIENLDEYVGLRCLFLETNGISKIENLEMLTELRCLYLSKNLISRIENIATLVNLDSIDLSHNLVAKIENLRNLPKFTKLILAHNKVQKISDLEELIYCDNISVLDLQHNQIDDPNVIEEIFAKMKSLRVLYLQGNQFMKNVKNYRKHVINL 1109
++L L IENLD L LFL TN I+K++NL+ L L L + N I++IE + LVNL + LSHN + IE L N K T L +A N+V+KI ++ L + D NQI++ + ++E+ KSL +YL+ N K+ + RK ++ L
Sbjct: 214 EMLELGSNRIRVIENLDGLTSLTSLFLGTNKINKLQNLDALHNLSVLSIQSNRITKIEGLQNLVNLKELYLSHNGIEVIEGLENNKKLTTLDIAANRVKKIENISHLTELQEFWMND---NQIENWSDLDEL-KNAKSLETVYLERNPLQKDPQYRRKIMLAL 372 HSP 2 Score: 73.559 bits (179), Expect = 1.422e-13 Identity = 58/153 (37.91%), Postives = 85/153 (55.56%), Query Frame = 3
Query: 615 LNDILYLHYKGFAFIENLDEYVGLRCLFLETNGISKIENLEMLTELRCLYLSKNLISRIENIATLVNLDSIDLSHNLVAKIENLRNLPKFTKLILAHNKVQKISDLEELIYCDNISVLDLQHNQIDDPNVIEEIFAKMKSLRVLYLQGNQFMK 1073
L D+ +H + IE L+ + L L N I KIENLE L+ LR L L N I ++EN+ L L+ +D+S N++ KIENL L + KL L HNK+ I++LE + + +L+L N+I VIE + + SL L+L N+ K
Sbjct: 103 LQDVDLVHCR-IGKIEGLEVLQKAKTLSLRQNLIKKIENLESLSSLRELDLYDNQIRKLENLDNLTELEQLDVSFNILRKIENLERLTQLKKLFLVHNKITGIANLEHFSF---LEMLELGSNRI---RVIENLDG-LTSLTSLFLGTNKINK 247 HSP 3 Score: 67.781 bits (164), Expect = 1.000e-11 Identity = 51/135 (37.78%), Postives = 73/135 (54.07%), Query Frame = 3
Query: 657 IENLDEYVGLRCLFLETNGISKIENLEMLTELRCLYLSKNLISRIENIATLVNLDSIDLSHNLVAKIENLRNLPKFTKLILAHNKVQKISDLEELIYCDNISVLDLQHNQIDDPNVIEEIFAKMKSLRVLYLQGN 1061
+ENLD L L + N + KIENLE LT+L+ L+L N I+ I N+ L+ ++L N + IENL L T L L NK+ K+ +L+ L N+SVL +Q N+I E + +L+ LYL N
Sbjct: 160 LENLDNLTELEQLDVSFNILRKIENLERLTQLKKLFLVHNKITGIANLEHFSFLEMLELGSNRIRVIENLDGLTSLTSLFLGTNKINKLQNLDAL---HNLSVLSIQSNRITKI----EGLQNLVNLKELYLSHN 287
BLAST of LRRC50 vs. Ensembl Medaka
Match: drc3 (dynein regulatory complex subunit 3 [Source:NCBI gene;Acc:101162841]) HSP 1 Score: 63.5438 bits (153), Expect = 3.747e-10 Identity = 53/181 (29.28%), Postives = 102/181 (56.35%), Query Frame = 3
Query: 699 LETNGISKIENLEMLTELRCLYLSKNLISRIENIATLVNLDSIDLSHNLVAKIENLRNLPKFTKLILAHNKVQKISDLEELIYCDNISVLDLQHNQIDD-PNVIEEIFAKMKSLRVLYLQGNQFMKNVKNYRKHVINLCKNLTYLDERPVFEKDRACAEAFCRGGIEEE-KDERNRWVAKE 1235
LE I +I++L+ T L L L+ NLI +I+ + +L+NL ++LS N + KI+ L +L K L L++N++ I +++ L DN++ + N ++ NV+ + K L +Y++GN F N +Y+ ++ NLT LD + + ++ + A + + IE+ ++E + +A+E
Sbjct: 43 LEYQNIQRIDSLQEYTSLVRLDLNNNLIKKIQGLDSLINLTWLNLSFNRIEKIQGLTSLQKLKVLNLSNNQITVIENMDTL---DNLTHFFIGCNLLNQLENVL--YLKRFKKLVHIYMKGNLF-SNEDDYQFFIVAFFPNLTVLDNKLILQELKEKASSKYQDDIEKRNQEESQKQLAEE 217 HSP 2 Score: 53.1434 bits (126), Expect = 5.233e-7 Identity = 39/110 (35.45%), Postives = 61/110 (55.45%), Query Frame = 3
Query: 657 IENLDEYVGLRCLFLETNGISKIENLEMLTELRCLYLSKNLISRIENIATLVNLDSIDLSHNLVAKIENLRNLPKFTKLILAHNKVQKISDLEE-----LIYCDNISVLD 971
I+ LD + L L L N I KI+ L L +L+ L LS N I+ IEN+ TL NL + NL+ ++EN+ L +F KL+ + K S+ ++ + + N++VLD
Sbjct: 73 IQGLDSLINLTWLNLSFNRIEKIQGLTSLQKLKVLNLSNNQITVIENMDTLDNLTHFFIGCNLLNQLENVLYLKRFKKLVHIYMKGNLFSNEDDYQFFIVAFFPNLTVLD 182
BLAST of LRRC50 vs. Ensembl Medaka
Match: drc3 (dynein regulatory complex subunit 3 [Source:NCBI gene;Acc:101162841]) HSP 1 Score: 60.8474 bits (146), Expect = 2.007e-9 Identity = 48/160 (30.00%), Postives = 89/160 (55.62%), Query Frame = 3
Query: 675 YVGLRCLFLETNGISKIENLEMLTELRCLYLSKNLISRIENIATLVNLDSIDLSHNLVAKIENLRNLPKFTKLILAHNKVQKISDLEELIYCDNISVLDLQHNQIDD-PNVIEEIFAKMKSLRVLYLQGNQFMKNVKNYRKHVINLCKNLTYLDERPVFE 1151
Y+G+ C I +I++L+ T L L L+ NLI +I+ + +L+NL ++LS N + KI+ L +L K L L++N++ I +++ L DN++ + N ++ NV+ + K L +Y++GN F N +Y+ ++ NLT LD + + +
Sbjct: 27 YMGVICF----ADIQRIDSLQEYTSLVRLDLNNNLIKKIQGLDSLINLTWLNLSFNRIEKIQGLTSLQKLKVLNLSNNQITVIENMDTL---DNLTHFFIGCNLLNQLENVL--YLKRFKKLVHIYMKGNLF-SNEDDYQFFIVAFFPNLTVLDNKLILQ 176 HSP 2 Score: 53.9138 bits (128), Expect = 3.549e-7 Identity = 41/110 (37.27%), Postives = 60/110 (54.55%), Query Frame = 3
Query: 657 IENLDEYVGLRCLFLETNGISKIENLEMLTELRCLYLSKNLISRIENIATLVNLDSIDLSHNLVAKIENLRNLPKFTKLILAHNKVQKIS---DLEELI--YCDNISVLD 971
I+ LD + L L L N I KI+ L L +L+ L LS N I+ IEN+ TL NL + NL+ ++EN+ L +F KL+ + K S D + I + N++VLD
Sbjct: 61 IQGLDSLINLTWLNLSFNRIEKIQGLTSLQKLKVLNLSNNQITVIENMDTLDNLTHFFIGCNLLNQLENVLYLKRFKKLVHIYMKGNLFSNEDDYQFFIVAFFPNLTVLD 170
BLAST of LRRC50 vs. Planmine SMEST
Match: SMESG000004118.1 (SMESG000004118.1) HSP 1 Score: 1140.95 bits (2950), Expect = 0.000e+0 Identity = 564/569 (99.12%), Postives = 566/569 (99.47%), Query Frame = 3
Query: 78 MNCNCDNFDCSMEDLKLISETTPISSVEEIDFKQENCVLDQKLDEIECENDMPSEYNFNSTNNNECDENEELIDENFNHNLNLKICDDETFNTCINAIEDPLKSSMCLDLSILTNISDDMEDEKIIQHPFNDISNINKEEKEQRKREIDAEIEKHKWPRMTTDYLKKHCKENKLYITPRLNDILYLHYKGFAFIENLDEYVGLRCLFLETNGISKIENLEMLTELRCLYLSKNLISRIENIATLVNLDSIDLSHNLVAKIENLRNLPKFTKLILAHNKVQKISDLEELIYCDNISVLDLQHNQIDDPNVIEEIFAKMKSLRVLYLQGNQFMKNVKNYRKHVINLCKNLTYLDERPVFEKDRACAEAFCRGGIEEEKDERNRWVAKEQKRMDDSFEWLRQRRAKIEAQNHELKLKNEKESLGESIADICVKPGEVDWLYGPQEVYDDLTTSNDAIDKSTLDEELDRPNSIFQIYTQNPEIPELVPSESFSSPKRILIQEVTTDVEETITLEPSCQNKMANKTAPIKAFLNESTNETREKNLEKIENLAAQAGSTCKNPFENDFLEIDSLE 1784
MNCNCDNFDCSMEDLKLISETT ISSVE+IDFKQENCVLDQKLDEIECENDMPSEYNFN TNNNECDENEE+IDENFNHNLNLKICDDETFNTCINAIEDPLKSSMCLDLSILTNISDDMEDEKIIQHPFNDISNINKEEKEQRKREIDAEIEKHKWPRMTTDYLKKHCKENKLYITPRLNDILYLHYKGFAFIENLDEYVGLRCLFLETNGISKIENLEMLTELRCLYLSKNLISRIENIATLVNLDSIDLSHNLVAKIENLRNLPKFTKLILAHNKVQKISDLEELIYCDNISVLDLQHNQIDDPNVIEEIFAKMKSLRVLYLQGNQFMKNVKNYRKHVINLCKNLTYLDERPVFEKDRACAEAFCRGGIEEEKDERNRWVAKEQKRMDDSFEWLRQRRAKIEAQNHELKLKNEKESLGESIADICVKPGEVDWLYGPQEVYDDLTTSNDAIDKSTLDEELDRPNSIFQIYTQNPEIPELVPSESFSSPKRILIQEV TDVEETITLEPSCQNKMANKTAPIKAFLNESTNETREKNLEKIENLAAQAGSTCKNPFENDFLEIDSLE
Sbjct: 1 MNCNCDNFDCSMEDLKLISETTQISSVEKIDFKQENCVLDQKLDEIECENDMPSEYNFNFTNNNECDENEEIIDENFNHNLNLKICDDETFNTCINAIEDPLKSSMCLDLSILTNISDDMEDEKIIQHPFNDISNINKEEKEQRKREIDAEIEKHKWPRMTTDYLKKHCKENKLYITPRLNDILYLHYKGFAFIENLDEYVGLRCLFLETNGISKIENLEMLTELRCLYLSKNLISRIENIATLVNLDSIDLSHNLVAKIENLRNLPKFTKLILAHNKVQKISDLEELIYCDNISVLDLQHNQIDDPNVIEEIFAKMKSLRVLYLQGNQFMKNVKNYRKHVINLCKNLTYLDERPVFEKDRACAEAFCRGGIEEEKDERNRWVAKEQKRMDDSFEWLRQRRAKIEAQNHELKLKNEKESLGESIADICVKPGEVDWLYGPQEVYDDLTTSNDAIDKSTLDEELDRPNSIFQIYTQNPEIPELVPSESFSSPKRILIQEVATDVEETITLEPSCQNKMANKTAPIKAFLNESTNETREKNLEKIENLAAQAGSTCKNPFENDFLEIDSLE 569
BLAST of LRRC50 vs. Planmine SMEST
Match: SMESG000004118.1 (SMESG000004118.1) HSP 1 Score: 1134.01 bits (2932), Expect = 0.000e+0 Identity = 563/570 (98.77%), Postives = 566/570 (99.30%), Query Frame = 3
Query: 78 MNCNCDNFDCSMEDLKLISETTPISSVEEIDFKQENCVLDQKLDEIECENDMPSEYNFNSTNNNECDENEELIDENFNHNLNLKICDDETFNTCINAIEDPLKSSMCLDLSILTNISDDMEDEKIIQHPFNDISNINKEEKEQRKREIDAEIEKHKWPRMTTDYLKKHCKENKLYITPRLNDILYLHYKGFAFIENLDEYVGLRCLFLETNGISKIENLEMLTELRCLYLSKNLISRIENIATLVNLDSIDLSHNLVAKIENLRNLPKFTKLILAHNKVQKISDLEELIYCDNISVLDLQHNQIDDPNVIEEIFAKMKSLRVLYLQGNQFMKNVKNYRKHVINLCKNLTYLDERPVFEKDRACAEAFCRGGIEEEKDERNRWVAKEQKRMDDSFEWLRQRRAKIEAQNHELKLKNEKESLGESIADICVKPGEVDWLYGPQEVYDDLTTSNDAIDKSTLDEELDRPNSIFQIYTQ-NPEIPELVPSESFSSPKRILIQEVTTDVEETITLEPSCQNKMANKTAPIKAFLNESTNETREKNLEKIENLAAQAGSTCKNPFENDFLEIDSLE 1784
MNCNCDNFDCSMEDLKLISETT ISSVE+IDFKQENCVLDQKLDEIECENDMPSEYNFN TNNNECDENEE+IDENFNHNLNLKICDDETFNTCINAIEDPLKSSMCLDLSILTNISDDMEDEKIIQHPFNDISNINKEEKEQRKREIDAEIEKHKWPRMTTDYLKKHCKENKLYITPRLNDILYLHYKGFAFIENLDEYVGLRCLFLETNGISKIENLEMLTELRCLYLSKNLISRIENIATLVNLDSIDLSHNLVAKIENLRNLPKFTKLILAHNKVQKISDLEELIYCDNISVLDLQHNQIDDPNVIEEIFAKMKSLRVLYLQGNQFMKNVKNYRKHVINLCKNLTYLDERPVFEKDRACAEAFCRGGIEEEKDERNRWVAKEQKRMDDSFEWLRQRRAKIEAQNHELKLKNEKESLGESIADICVKPGEVDWLYGPQEVYDDLTTSNDAIDKSTLDEELDRPNSIFQIYTQ +PEIPELVPSESFSSPKRILIQEV TDVEETITLEPSCQNKMANKTAPIKAFLNESTNETREKNLEKIENLAAQAGSTCKNPFENDFLEIDSLE
Sbjct: 1 MNCNCDNFDCSMEDLKLISETTQISSVEKIDFKQENCVLDQKLDEIECENDMPSEYNFNFTNNNECDENEEIIDENFNHNLNLKICDDETFNTCINAIEDPLKSSMCLDLSILTNISDDMEDEKIIQHPFNDISNINKEEKEQRKREIDAEIEKHKWPRMTTDYLKKHCKENKLYITPRLNDILYLHYKGFAFIENLDEYVGLRCLFLETNGISKIENLEMLTELRCLYLSKNLISRIENIATLVNLDSIDLSHNLVAKIENLRNLPKFTKLILAHNKVQKISDLEELIYCDNISVLDLQHNQIDDPNVIEEIFAKMKSLRVLYLQGNQFMKNVKNYRKHVINLCKNLTYLDERPVFEKDRACAEAFCRGGIEEEKDERNRWVAKEQKRMDDSFEWLRQRRAKIEAQNHELKLKNEKESLGESIADICVKPGEVDWLYGPQEVYDDLTTSNDAIDKSTLDEELDRPNSIFQIYTQTDPEIPELVPSESFSSPKRILIQEVATDVEETITLEPSCQNKMANKTAPIKAFLNESTNETREKNLEKIENLAAQAGSTCKNPFENDFLEIDSLE 570
BLAST of LRRC50 vs. Planmine SMEST
Match: SMESG000004112.1 (SMESG000004112.1) HSP 1 Score: 1075.46 bits (2780), Expect = 0.000e+0 Identity = 540/569 (94.90%), Postives = 541/569 (95.08%), Query Frame = 3
Query: 78 MNCNCDNFDCSMEDLKLISETTPISSVEEIDFKQENCVLDQKLDEIECENDMPSEYNFNSTNNNECDENEELIDENFNHNLNLKICDDETFNTCINAIEDPLKSSMCLDLSILTNISDDMEDEKIIQHPFNDISNINKEEKEQRKREIDAEIEKHKWPRMTTDYLKKHCKENKLYITPRLNDILYLHYKGFAFIENLDEYVGLRCLFLETNGISKIENLEMLTELRCLYLSKNLISRIENIATLVNLDSIDLSHNLVAKIENLRNLPKFTKLILAHNKVQKISDLEELIYCDNISVLDLQHNQIDDPNVIEEIFAKMKSLRVLYLQGNQFMKNVKNYRKHVINLCKNLTYLDERPVFEKDRACAEAFCRGGIEEEKDERNRWVAKEQKRMDDSFEWLRQRRAKIEAQNHELKLKNEKESLGESIADICVKPGEVDWLYGPQEVYDDLTTSNDAIDKSTLDEELDRPNSIFQIYTQNPEIPELVPSESFSSPKRILIQEVTTDVEETITLEPSCQNKMANKTAPIKAFLNESTNETREKNLEKIENLAAQAGSTCKNPFENDFLEIDSLE 1784
MNCNCDNFDCSMEDLKLISETTPISSVEEIDFKQENCVLDQKLDEIECENDMPSEYNFN TNNNECDENEELIDENFNHNLNLKICDDETFNTCINAIEDPLKSSMCLDLSILTNISDDMEDEKIIQHPFNDISNINKEEKEQRKREIDAEIEKHKWPRMTTDYLKKHCKENKLYITPRLNDILYLHYKGFAFIENLDEYVGLRCLFLETNGISKIENLEMLTELRCLYLSKNLISRIENIATLVNLDSIDLSHNLVAKIENLRNLPKFTKLILAHNKVQKISDLEELIYCDNISVLDLQHNQIDDPNVIEEIFAKMKSL KNLTYLDERPVFEKDRACAEAFCRGGIEEEKDER+RWVAKEQKRMD SFEWLRQRRAKIEAQNHELKLKNEKESLGESIADICVKPGEVDWLYGPQEVYDDLTTSNDAIDKSTLDEELDRPNSIFQIYTQNPEIPELVPSESFSSPKRILIQEV TDVEETITLEPSCQNKMANKTAPIKAFLNESTNETREKNLEKIENLAAQAGSTCKNPFENDFLEIDSLE
Sbjct: 1 MNCNCDNFDCSMEDLKLISETTPISSVEEIDFKQENCVLDQKLDEIECENDMPSEYNFNFTNNNECDENEELIDENFNHNLNLKICDDETFNTCINAIEDPLKSSMCLDLSILTNISDDMEDEKIIQHPFNDISNINKEEKEQRKREIDAEIEKHKWPRMTTDYLKKHCKENKLYITPRLNDILYLHYKGFAFIENLDEYVGLRCLFLETNGISKIENLEMLTELRCLYLSKNLISRIENIATLVNLDSIDLSHNLVAKIENLRNLPKFTKLILAHNKVQKISDLEELIYCDNISVLDLQHNQIDDPNVIEEIFAKMKSL-------------------------KNLTYLDERPVFEKDRACAEAFCRGGIEEEKDERDRWVAKEQKRMDGSFEWLRQRRAKIEAQNHELKLKNEKESLGESIADICVKPGEVDWLYGPQEVYDDLTTSNDAIDKSTLDEELDRPNSIFQIYTQNPEIPELVPSESFSSPKRILIQEVATDVEETITLEPSCQNKMANKTAPIKAFLNESTNETREKNLEKIENLAAQAGSTCKNPFENDFLEIDSLE 544
BLAST of LRRC50 vs. Planmine SMEST
Match: SMESG000004112.1 (SMESG000004112.1) HSP 1 Score: 1068.53 bits (2762), Expect = 0.000e+0 Identity = 539/570 (94.56%), Postives = 541/570 (94.91%), Query Frame = 3
Query: 78 MNCNCDNFDCSMEDLKLISETTPISSVEEIDFKQENCVLDQKLDEIECENDMPSEYNFNSTNNNECDENEELIDENFNHNLNLKICDDETFNTCINAIEDPLKSSMCLDLSILTNISDDMEDEKIIQHPFNDISNINKEEKEQRKREIDAEIEKHKWPRMTTDYLKKHCKENKLYITPRLNDILYLHYKGFAFIENLDEYVGLRCLFLETNGISKIENLEMLTELRCLYLSKNLISRIENIATLVNLDSIDLSHNLVAKIENLRNLPKFTKLILAHNKVQKISDLEELIYCDNISVLDLQHNQIDDPNVIEEIFAKMKSLRVLYLQGNQFMKNVKNYRKHVINLCKNLTYLDERPVFEKDRACAEAFCRGGIEEEKDERNRWVAKEQKRMDDSFEWLRQRRAKIEAQNHELKLKNEKESLGESIADICVKPGEVDWLYGPQEVYDDLTTSNDAIDKSTLDEELDRPNSIFQIYTQ-NPEIPELVPSESFSSPKRILIQEVTTDVEETITLEPSCQNKMANKTAPIKAFLNESTNETREKNLEKIENLAAQAGSTCKNPFENDFLEIDSLE 1784
MNCNCDNFDCSMEDLKLISETTPISSVEEIDFKQENCVLDQKLDEIECENDMPSEYNFN TNNNECDENEELIDENFNHNLNLKICDDETFNTCINAIEDPLKSSMCLDLSILTNISDDMEDEKIIQHPFNDISNINKEEKEQRKREIDAEIEKHKWPRMTTDYLKKHCKENKLYITPRLNDILYLHYKGFAFIENLDEYVGLRCLFLETNGISKIENLEMLTELRCLYLSKNLISRIENIATLVNLDSIDLSHNLVAKIENLRNLPKFTKLILAHNKVQKISDLEELIYCDNISVLDLQHNQIDDPNVIEEIFAKMKSL KNLTYLDERPVFEKDRACAEAFCRGGIEEEKDER+RWVAKEQKRMD SFEWLRQRRAKIEAQNHELKLKNEKESLGESIADICVKPGEVDWLYGPQEVYDDLTTSNDAIDKSTLDEELDRPNSIFQIYTQ +PEIPELVPSESFSSPKRILIQEV TDVEETITLEPSCQNKMANKTAPIKAFLNESTNETREKNLEKIENLAAQAGSTCKNPFENDFLEIDSLE
Sbjct: 1 MNCNCDNFDCSMEDLKLISETTPISSVEEIDFKQENCVLDQKLDEIECENDMPSEYNFNFTNNNECDENEELIDENFNHNLNLKICDDETFNTCINAIEDPLKSSMCLDLSILTNISDDMEDEKIIQHPFNDISNINKEEKEQRKREIDAEIEKHKWPRMTTDYLKKHCKENKLYITPRLNDILYLHYKGFAFIENLDEYVGLRCLFLETNGISKIENLEMLTELRCLYLSKNLISRIENIATLVNLDSIDLSHNLVAKIENLRNLPKFTKLILAHNKVQKISDLEELIYCDNISVLDLQHNQIDDPNVIEEIFAKMKSL-------------------------KNLTYLDERPVFEKDRACAEAFCRGGIEEEKDERDRWVAKEQKRMDGSFEWLRQRRAKIEAQNHELKLKNEKESLGESIADICVKPGEVDWLYGPQEVYDDLTTSNDAIDKSTLDEELDRPNSIFQIYTQTDPEIPELVPSESFSSPKRILIQEVATDVEETITLEPSCQNKMANKTAPIKAFLNESTNETREKNLEKIENLAAQAGSTCKNPFENDFLEIDSLE 545
BLAST of LRRC50 vs. Planmine SMEST
Match: SMESG000026105.1 (SMESG000026105.1) HSP 1 Score: 78.1814 bits (191), Expect = 1.896e-15 Identity = 60/177 (33.90%), Postives = 92/177 (51.98%), Query Frame = 3
Query: 621 DILYLHYKGFAFIENLDEYVGLRCLFLETNGISKIENLEMLTELRCLYLSKNLISRIENIATLVNLDSIDLSHNLVAKIENLRNLPKFTKLILAHNKVQKISDLEELIYCDNISVLDLQHNQIDDPNVIEEIFAKMKSLRVLYLQGNQFM------KNVKNYRKHVINLCKNLTYLD 1133
++L L IENLD L L+L N ISK+ENL+ + L L + N I++I+ + L+NL+ + LSHN ++KIENL NL K T L L+ N++ K+ +L L + D N + D N I+E+ ++ L +Y + N K NYR+ + L L +D
Sbjct: 138 EMLELGSNSIKRIENLDSLTKLDQLYLGKNKISKLENLDFMKNLTVLSIQGNRITQIDGLDNLINLEQLYLSHNGISKIENLGNLTKLTTLDLSSNRISKVENLSHLKILEEFWFND---NNLADWNSIDEL-VNLEKLATVYFERNPIWYTPDRSKEDPNYRRKIRLLLPKLKQID 310 The following BLAST results are available for this feature:
BLAST of LRRC50 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of LRRC50 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 4
BLAST of LRRC50 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of LRRC50 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of LRRC50 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of LRRC50 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of LRRC50 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of LRRC50 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of LRRC50 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of LRRC50 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of LRRC50 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 1
BLAST of LRRC50 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of LRRC50 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of LRRC50 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Cross References
External references for this transcript
Sequences
The following sequences are available for this feature:
transcript sequence >SMED30008476 ID=SMED30008476|Name=LRRC50|organism=Schmidtea mediterranea sexual|type=transcript|length=1813bpback to top protein sequence of SMED30008476-orf-1 >SMED30008476-orf-1 ID=SMED30008476-orf-1|Name=SMED30008476-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=595bp LICLTSNLPRKLGYDFFVLSYIVNKMNCNCDNFDCSMEDLKLISETTPISback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
|
