10-formyltetrahydrofolate dehydrogenase
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30008441 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 12
Homology
BLAST of 10-formyltetrahydrofolate dehydrogenase vs. Ensembl Human
Match: ALDH1L2 (aldehyde dehydrogenase 1 family member L2 [Source:HGNC Symbol;Acc:HGNC:26777]) HSP 1 Score: 1125.15 bits (2909), Expect = 0.000e+0 Identity = 552/863 (63.96%), Postives = 684/863 (79.26%), Query Frame = 3
Query: 438 AMEAIDLGTKVFKIPKWRVNNQIIKEVFEEYRSINAELNVLAFCTQFIPMEVINAPKHRSIIYHPSLLPKHRGASAINWTLINGDLKGGLTIFWADDGLDTGPVLLQRECDVHINDTVDSLYSRFMMPEGIKAMVEAVRQIESGRAPAIAQYHPDHSYDQMVKKSTAEINWNQSGLSLHNFIRGHDKVPGAWSWINGQKVTFYGSQLWYHDVVHDGPSLAIQGLSDPAVLHNHGLLIRGSDNQWINIAQLKFEDTGKTVQASKYGKGDEITTMADLSEDERAMEIPLMKIWKSILMGSDI-EPESDFFKLGGTSMDVTRIIEQI--KCNFNVELKIDHIYLYSTFDTLFKWIVLRKRGGGSQKKLHYDAVIINANKMTFPIPHQIFINNEFVNSESGKEYDSKNPSDESVICRVSYSSXXXXXXXXXXXXXXFEFGEWGKMSARDRGRILYKLADLMEEHAEELATLESLDSGAVYTLALKTHIGMSIETFRYFAGWCDKIQGSTIPISNARPNKNLSFTKKEPIGVCGIITPWNYPLMMLAWKVAACLAAGNTVVLKPAQVTPLASLKFCELSVEAGFPPGVINVLPGSGAIAGTAISEHPDIRKLGFTGSTAIGQTIMSSCAKSNLKKCSLELGGKSPLIIFSDCDMDKAVKSACSSVFFNKGENCIAAGRIFVDVRIHDVFLKLVVEDVKKMKIGDPLDRSVDHGPQNHEIHLLKLLEFCDIGVKEGAKLVFGGKRCDRKGYFMEPTIFTSVTDDMYIAREESFGPIMIISKFY--DIDEVIVRANKTEYGLASGVFTNDISKALRVADAIDAGTVFINTYNKTDVAAPFGGFKQSGFGKDLGQEALNEYLKTKTVTVEY 3011
A+ A GT VFK+PKWRV + IKEV E YRS+ AELNVL FCTQFIPM++I++PKH SIIYHPS+LP+HRGASAINWTLI GD K G ++FWADDGLDTGP+LLQR CDV NDTVD+LY+RF+ PEGIKAMVEAV+ I G+AP I Q +Y+ + KK AEI+W+QS LHN+IRGHDKVPGAW+ INGQ VTFYGS L + V G L I+G P ++ +GL++ G+D + + + L+FED GK + AS+Y E T++ +L+ +E + + IW IL I E +DFFK G +SMDV R++E+I KC ++L+ + +Y+ + F+ + +V + RG + +L D + N++ +P+Q FIN +F +++ GK YD+ NP+D S IC+VSY+S DVD AV AAK+AFE GEWG+M+AR+RGR++Y+LADL+EE+ EELAT+E+LDSGAVYTLALKTHIGMS++TFRYFAGWCDKIQGSTIPI+ ARPN+NL+FTKKEP+GVC II PWNYPLMMLAWK AACLAAGNT+VLKPAQVTPL +LKF ELSV+AGFP GVIN++PGSG IAG +SEHPDIRKLGFTGST IG+ IM SCA SNLKK SLELGGKSPLIIF+DC++DKAV+ +VFFNKGENCIAAGR+FV+ IHD F+ VVE++KKMKIGDPLDRS DHGPQNH+ HL KLL++C+ GVKEGA LV+GG++ R G+FMEPT+FT V D MY+A+EESFGPIM+ISKF DID V+ RAN TEYGLASGVFT DI+KA+ V++ ++AGTVFINTYNKTDVAAPFGG KQSGFGKDLG+EALNEYLKTKTVT+EY
Sbjct: 65 ALAAEKDGTPVFKLPKWRVKGKTIKEVAEAYRSVGAELNVLPFCTQFIPMDIIDSPKHGSIIYHPSILPRHRGASAINWTLIMGDKKAGFSVFWADDGLDTGPILLQRSCDVEPNDTVDALYNRFLFPEGIKAMVEAVQLIADGKAPRIPQPEEGATYEGIQKKENAEISWDQSAEVLHNWIRGHDKVPGAWTEINGQMVTFYGSTL-LNSSVPPGEPLEIKGAKKPGLVTKNGLVLFGNDGKALTVRNLQFED-GKMIPASQYFSTGE-TSVVELTAEEVKVAETIKVIWAGILSNVPIIEDSTDFFKSGASSMDVARLVEEIRQKCG-GLQLQNEDVYMATKFEGFIQKVVRKLRGEDQEVELVVDYISKEVNEIMVKMPYQCFINGQFTDADDGKTYDTINPTDGSTICKVSYASLADVDKAVAAAKDAFENGEWGRMNARERGRLMYRLADLLEENQEELATIEALDSGAVYTLALKTHIGMSVQTFRYFAGWCDKIQGSTIPINQARPNRNLTFTKKEPLGVCAIIIPWNYPLMMLAWKSAACLAAGNTLVLKPAQVTPLTALKFAELSVKAGFPKGVINIIPGSGGIAGQRLSEHPDIRKLGFTGSTPIGKQIMKSCAVSNLKKVSLELGGKSPLIIFNDCELDKAVRMGMGAVFFNKGENCIAAGRLFVEESIHDEFVTRVVEEIKKMKIGDPLDRSTDHGPQNHKAHLEKLLQYCETGVKEGATLVYGGRQVQRPGFFMEPTVFTDVEDYMYLAKEESFGPIMVISKFQNGDIDGVLQRANSTEYGLASGVFTRDINKAMYVSEKLEAGTVFINTYNKTDVAAPFGGVKQSGFGKDLGEEALNEYLKTKTVTLEY 923 HSP 2 Score: 70.8626 bits (172), Expect = 1.341e-11 Identity = 26/48 (54.17%), Postives = 40/48 (83.33%), Query Frame = 1
Query: 103 FNPRMKIAIIGQSIFGAQVYKELKNEGHDIVGVFTIPDRNGRSDPLGI 246
F ++K+A+IGQS+FG +VY L+ EGH +VGVFT+PD++G++DPL +
Sbjct: 19 FKNKLKLALIGQSLFGQEVYSHLRKEGHRVVGVFTVPDKDGKADPLAL 66
BLAST of 10-formyltetrahydrofolate dehydrogenase vs. Ensembl Human
Match: ALDH1L2 (aldehyde dehydrogenase 1 family member L2 [Source:HGNC Symbol;Acc:HGNC:26777]) HSP 1 Score: 1123.61 bits (2905), Expect = 0.000e+0 Identity = 552/863 (63.96%), Postives = 684/863 (79.26%), Query Frame = 3
Query: 438 AMEAIDLGTKVFKIPKWRVNNQIIKEVFEEYRSINAELNVLAFCTQFIPMEVINAPKHRSIIYHPSLLPKHRGASAINWTLINGDLKGGLTIFWADDGLDTGPVLLQRECDVHINDTVDSLYSRFMMPEGIKAMVEAVRQIESGRAPAIAQYHPDHSYDQMVKKSTAEINWNQSGLSLHNFIRGHDKVPGAWSWINGQKVTFYGSQLWYHDVVHDGPSLAIQGLSDPAVLHNHGLLIRGSDNQWINIAQLKFEDTGKTVQASKYGKGDEITTMADLSEDERAMEIPLMKIWKSILMGSDI-EPESDFFKLGGTSMDVTRIIEQI--KCNFNVELKIDHIYLYSTFDTLFKWIVLRKRGGGSQKKLHYDAVIINANKMTFPIPHQIFINNEFVNSESGKEYDSKNPSDESVICRVSYSSXXXXXXXXXXXXXXFEFGEWGKMSARDRGRILYKLADLMEEHAEELATLESLDSGAVYTLALKTHIGMSIETFRYFAGWCDKIQGSTIPISNARPNKNLSFTKKEPIGVCGIITPWNYPLMMLAWKVAACLAAGNTVVLKPAQVTPLASLKFCELSVEAGFPPGVINVLPGSGAIAGTAISEHPDIRKLGFTGSTAIGQTIMSSCAKSNLKKCSLELGGKSPLIIFSDCDMDKAVKSACSSVFFNKGENCIAAGRIFVDVRIHDVFLKLVVEDVKKMKIGDPLDRSVDHGPQNHEIHLLKLLEFCDIGVKEGAKLVFGGKRCDRKGYFMEPTIFTSVTDDMYIAREESFGPIMIISKFY--DIDEVIVRANKTEYGLASGVFTNDISKALRVADAIDAGTVFINTYNKTDVAAPFGGFKQSGFGKDLGQEALNEYLKTKTVTVEY 3011
A+ A GT VFK+PKWRV + IKEV E YRS+ AELNVL FCTQFIPM++I++PKH SIIYHPS+LP+HRGASAINWTLI GD K G ++FWADDGLDTGP+LLQR CDV NDTVD+LY+RF+ PEGIKAMVEAV+ I G+AP I Q +Y+ + KK AEI+W+QS LHN+IRGHDKVPGAW+ INGQ VTFYGS L + V G L I+G P ++ +GL++ G+D + + + L+FED GK + AS+Y E T++ +L+ +E + + IW IL I E +DFFK G +SMDV R++E+I KC ++L+ + +Y+ + F+ + +V + RG + +L D + N++ +P+Q FIN +F +++ GK YD+ NP+D S IC+VSY+S DVD AV AAK+AFE GEWG+M+AR+RGR++Y+LADL+EE+ EELAT+E+LDSGAVYTLALKTHIGMS++TFRYFAGWCDKIQGSTIPI+ ARPN+NL+FTKKEP+GVC II PWNYPLMMLAWK AACLAAGNT+VLKPAQVTPL +LKF ELSV+AGFP GVIN++PGSG IAG +SEHPDIRKLGFTGST IG+ IM SCA SNLKK SLELGGKSPLIIF+DC++DKAV+ +VFFNKGENCIAAGR+FV+ IHD F+ VVE++KKMKIGDPLDRS DHGPQNH+ HL KLL++C+ GVKEGA LV+GG++ R G+FMEPT+FT V D MY+A+EESFGPIM+ISKF DID V+ RAN TEYGLASGVFT DI+KA+ V++ ++AGTVFINTYNKTDVAAPFGG KQSGFGKDLG+EALNEYLKTKTVT+EY
Sbjct: 74 ALAAEKDGTPVFKLPKWRVKGKTIKEVAEAYRSVGAELNVLPFCTQFIPMDIIDSPKHGSIIYHPSILPRHRGASAINWTLIMGDKKAGFSVFWADDGLDTGPILLQRSCDVEPNDTVDALYNRFLFPEGIKAMVEAVQLIADGKAPRIPQPEEGATYEGIQKKENAEISWDQSAEVLHNWIRGHDKVPGAWTEINGQMVTFYGSTL-LNSSVPPGEPLEIKGAKKPGLVTKNGLVLFGNDGKALTVRNLQFED-GKMIPASQYFSTGE-TSVVELTAEEVKVAETIKVIWAGILSNVPIIEDSTDFFKSGASSMDVARLVEEIRQKCG-GLQLQNEDVYMATKFEGFIQKVVRKLRGEDQEVELVVDYISKEVNEIMVKMPYQCFINGQFTDADDGKTYDTINPTDGSTICKVSYASLADVDKAVAAAKDAFENGEWGRMNARERGRLMYRLADLLEENQEELATIEALDSGAVYTLALKTHIGMSVQTFRYFAGWCDKIQGSTIPINQARPNRNLTFTKKEPLGVCAIIIPWNYPLMMLAWKSAACLAAGNTLVLKPAQVTPLTALKFAELSVKAGFPKGVINIIPGSGGIAGQRLSEHPDIRKLGFTGSTPIGKQIMKSCAVSNLKKVSLELGGKSPLIIFNDCELDKAVRMGMGAVFFNKGENCIAAGRLFVEESIHDEFVTRVVEEIKKMKIGDPLDRSTDHGPQNHKAHLEKLLQYCETGVKEGATLVYGGRQVQRPGFFMEPTVFTDVEDYMYLAKEESFGPIMVISKFQNGDIDGVLQRANSTEYGLASGVFTRDINKAMYVSEKLEAGTVFINTYNKTDVAAPFGGVKQSGFGKDLGEEALNEYLKTKTVTLEY 932 HSP 2 Score: 70.8626 bits (172), Expect = 1.347e-11 Identity = 26/48 (54.17%), Postives = 40/48 (83.33%), Query Frame = 1
Query: 103 FNPRMKIAIIGQSIFGAQVYKELKNEGHDIVGVFTIPDRNGRSDPLGI 246
F ++K+A+IGQS+FG +VY L+ EGH +VGVFT+PD++G++DPL +
Sbjct: 28 FKNKLKLALIGQSLFGQEVYSHLRKEGHRVVGVFTVPDKDGKADPLAL 75
BLAST of 10-formyltetrahydrofolate dehydrogenase vs. Ensembl Human
Match: ALDH1L1 (aldehyde dehydrogenase 1 family member L1 [Source:HGNC Symbol;Acc:HGNC:3978]) HSP 1 Score: 1063.91 bits (2750), Expect = 0.000e+0 Identity = 516/863 (59.79%), Postives = 668/863 (77.40%), Query Frame = 3
Query: 438 AMEAIDLGTKVFKIPKWRVNNQIIKEVFEEYRSINAELNVLAFCTQFIPMEVINAPKHRSIIYHPSLLPKHRGASAINWTLINGDLKGGLTIFWADDGLDTGPVLLQRECDVHINDTVDSLYSRFMMPEGIKAMVEAVRQIESGRAPAIAQYHPDHSYDQMVKKSTAEINWNQSGLSLHNFIRGHDKVPGAWSWINGQKVTFYGSQLWYHDVVHDGPSLAIQGLSDPAVLHNHGLLIRGSDNQWINIAQLKFEDTGKTVQASKYGKGDEITTMADLSEDERAMEIPLMKIWKSILMGS-DIEPESDFFKLGGTSMDVTRIIEQIK--CNFNVELKIDHIYLYSTFDTLFKWIVLRKRGGGSQKKLHYDAVIINANKMTFPIPHQIFINNEFVNSESGKEYDSKNPSDESVICRVSYSSXXXXXXXXXXXXXXFEFGEWGKMSARDRGRILYKLADLMEEHAEELATLESLDSGAVYTLALKTHIGMSIETFRYFAGWCDKIQGSTIPISNARPNKNLSFTKKEPIGVCGIITPWNYPLMMLAWKVAACLAAGNTVVLKPAQVTPLASLKFCELSVEAGFPPGVINVLPGSGAIAGTAISEHPDIRKLGFTGSTAIGQTIMSSCAKSNLKKCSLELGGKSPLIIFSDCDMDKAVKSACSSVFFNKGENCIAAGRIFVDVRIHDVFLKLVVEDVKKMKIGDPLDRSVDHGPQNHEIHLLKLLEFCDIGVKEGAKLVFGGKRCDRKGYFMEPTIFTSVTDDMYIAREESFGPIMIISKFY--DIDEVIVRANKTEYGLASGVFTNDISKALRVADAIDAGTVFINTYNKTDVAAPFGGFKQSGFGKDLGQEALNEYLKTKTVTVEY 3011
+EA G VFK +WR Q + +V +Y+++ AELNVL FC+QFIPME+I+AP+H SIIYHPSLLP+HRGASAINWTLI+GD KGG +IFWADDGLDTG +LLQ+EC+V +DTV +LY+RF+ PEGIK MV+AVR I G+AP + Q +Y+ + KK TA+INW+Q ++HN+IRG+DKVPGAW+ QK+TF+ S L +V +G +L I G P V+ GL++ G+D++ + + ++ ED GK + AS + KG +++ +L+E E + +W+ IL ++E +DFFK G S+DV R++E++K C+ +EL+ + +Y+ STF + +V + RG + + D V + NK T +PHQ+FI EFV++E K ++ NP+D SVIC+VS + DVD AV AAK+AFE G WGK+SARDRGR++Y+LADLME+H EELAT+E+LD+GAVYTLALKTH+GMSI+TFRYFAGWCDKIQGSTIPI+ ARPN+NL+ T+KEP+GVCGII PWNYPLMML+WK AACLAAGNTVV+KPAQVTPL +LKF EL+++AG P GV+NVLPGSG++ G +S+HPD+RK+GFTGST +G+ IM SCA SN+KK SLELGGKSPLIIF+DCD++KAV+ SSVFFNKGENCIAAGR+FV+ IHD F++ VVE+V+KMK+G+PLDR DHGPQNH HL+KL+E+C GVKEGA LV GG + R G+F EPT+FT V D M+IA+EESFGP+MIIS+F D+D V+ RAN TE+GLASGVFT DI+KAL V+D + AGTVF+NTYNKTDVAAPFGGFKQSGFGKDLG+ ALNEYL+ KTVT EY
Sbjct: 53 GLEAEKDGVPVFKYSRWRAKGQALPDVVAKYQALGAELNVLPFCSQFIPMEIISAPRHGSIIYHPSLLPRHRGASAINWTLIHGDKKGGFSIFWADDGLDTGDLLLQKECEVLPDDTVSTLYNRFLFPEGIKGMVQAVRLIAEGKAPRLPQPEEGATYEGIQKKETAKINWDQPAEAIHNWIRGNDKVPGAWTEACEQKLTFFNSTLNTSGLVPEGDALPIPGAHRPGVVTKAGLILFGNDDKMLLVKNIQLED-GKMILASNFFKG-AASSVLELTEAELVTAEAVRSVWQRILPKVLEVEDSTDFFKSGAASVDVVRLVEEVKELCD-GLELENEDVYMASTFGDFIQLLVRKLRGDDEEGECSIDYVEMAVNKRTVRMPHQLFIGGEFVDAEGAKTSETINPTDGSVICQVSLAQVTDVDKAVAAAKDAFENGRWGKISARDRGRLMYRLADLMEQHQEELATIEALDAGAVYTLALKTHVGMSIQTFRYFAGWCDKIQGSTIPINQARPNRNLTLTRKEPVGVCGIIIPWNYPLMMLSWKTAACLAAGNTVVIKPAQVTPLTALKFAELTLKAGIPKGVVNVLPGSGSLVGQRLSDHPDVRKIGFTGSTEVGKHIMKSCAISNVKKVSLELGGKSPLIIFADCDLNKAVQMGMSSVFFNKGENCIAAGRLFVEDSIHDEFVRRVVEEVRKMKVGNPLDRDTDHGPQNHHAHLVKLMEYCQHGVKEGATLVCGGNQVPRPGFFFEPTVFTDVEDHMFIAKEESFGPVMIISRFADGDLDAVLSRANATEFGLASGVFTRDINKALYVSDKLQAGTVFVNTYNKTDVAAPFGGFKQSGFGKDLGEAALNEYLRVKTVTFEY 912 HSP 2 Score: 72.7886 bits (177), Expect = 3.222e-12 Identity = 31/66 (46.97%), Postives = 49/66 (74.24%), Query Frame = 1
Query: 115 MKIAIIGQSIFGAQVYKELKNEGHDIVGVFTIPDRNGRSDPLGIFYWE*GFTTLLMTSKKSQGRPL 312
MKIA+IGQS+FG +VY L+ EGH++VGVFT+PD++G++DPLG+ + G + +++G+ L
Sbjct: 11 MKIAVIGQSLFGQEVYCHLRKEGHEVVGVFTVPDKDGKADPLGLEAEKDGVPVFKYSRWRAKGQAL 76
BLAST of 10-formyltetrahydrofolate dehydrogenase vs. Ensembl Human
Match: ALDH1L1 (aldehyde dehydrogenase 1 family member L1 [Source:HGNC Symbol;Acc:HGNC:3978]) HSP 1 Score: 1063.52 bits (2749), Expect = 0.000e+0 Identity = 516/863 (59.79%), Postives = 668/863 (77.40%), Query Frame = 3
Query: 438 AMEAIDLGTKVFKIPKWRVNNQIIKEVFEEYRSINAELNVLAFCTQFIPMEVINAPKHRSIIYHPSLLPKHRGASAINWTLINGDLKGGLTIFWADDGLDTGPVLLQRECDVHINDTVDSLYSRFMMPEGIKAMVEAVRQIESGRAPAIAQYHPDHSYDQMVKKSTAEINWNQSGLSLHNFIRGHDKVPGAWSWINGQKVTFYGSQLWYHDVVHDGPSLAIQGLSDPAVLHNHGLLIRGSDNQWINIAQLKFEDTGKTVQASKYGKGDEITTMADLSEDERAMEIPLMKIWKSILMGS-DIEPESDFFKLGGTSMDVTRIIEQIK--CNFNVELKIDHIYLYSTFDTLFKWIVLRKRGGGSQKKLHYDAVIINANKMTFPIPHQIFINNEFVNSESGKEYDSKNPSDESVICRVSYSSXXXXXXXXXXXXXXFEFGEWGKMSARDRGRILYKLADLMEEHAEELATLESLDSGAVYTLALKTHIGMSIETFRYFAGWCDKIQGSTIPISNARPNKNLSFTKKEPIGVCGIITPWNYPLMMLAWKVAACLAAGNTVVLKPAQVTPLASLKFCELSVEAGFPPGVINVLPGSGAIAGTAISEHPDIRKLGFTGSTAIGQTIMSSCAKSNLKKCSLELGGKSPLIIFSDCDMDKAVKSACSSVFFNKGENCIAAGRIFVDVRIHDVFLKLVVEDVKKMKIGDPLDRSVDHGPQNHEIHLLKLLEFCDIGVKEGAKLVFGGKRCDRKGYFMEPTIFTSVTDDMYIAREESFGPIMIISKFY--DIDEVIVRANKTEYGLASGVFTNDISKALRVADAIDAGTVFINTYNKTDVAAPFGGFKQSGFGKDLGQEALNEYLKTKTVTVEY 3011
+EA G VFK +WR Q + +V +Y+++ AELNVL FC+QFIPME+I+AP+H SIIYHPSLLP+HRGASAINWTLI+GD KGG +IFWADDGLDTG +LLQ+EC+V +DTV +LY+RF+ PEGIK MV+AVR I G+AP + Q +Y+ + KK TA+INW+Q ++HN+IRG+DKVPGAW+ QK+TF+ S L +V +G +L I G P V+ GL++ G+D++ + + ++ ED GK + AS + KG +++ +L+E E + +W+ IL ++E +DFFK G S+DV R++E++K C+ +EL+ + +Y+ STF + +V + RG + + D V + NK T +PHQ+FI EFV++E K ++ NP+D SVIC+VS + DVD AV AAK+AFE G WGK+SARDRGR++Y+LADLME+H EELAT+E+LD+GAVYTLALKTH+GMSI+TFRYFAGWCDKIQGSTIPI+ ARPN+NL+ T+KEP+GVCGII PWNYPLMML+WK AACLAAGNTVV+KPAQVTPL +LKF EL+++AG P GV+NVLPGSG++ G +S+HPD+RK+GFTGST +G+ IM SCA SN+KK SLELGGKSPLIIF+DCD++KAV+ SSVFFNKGENCIAAGR+FV+ IHD F++ VVE+V+KMK+G+PLDR DHGPQNH HL+KL+E+C GVKEGA LV GG + R G+F EPT+FT V D M+IA+EESFGP+MIIS+F D+D V+ RAN TE+GLASGVFT DI+KAL V+D + AGTVF+NTYNKTDVAAPFGGFKQSGFGKDLG+ ALNEYL+ KTVT EY
Sbjct: 43 GLEAEKDGVPVFKYSRWRAKGQALPDVVAKYQALGAELNVLPFCSQFIPMEIISAPRHGSIIYHPSLLPRHRGASAINWTLIHGDKKGGFSIFWADDGLDTGDLLLQKECEVLPDDTVSTLYNRFLFPEGIKGMVQAVRLIAEGKAPRLPQPEEGATYEGIQKKETAKINWDQPAEAIHNWIRGNDKVPGAWTEACEQKLTFFNSTLNTSGLVPEGDALPIPGAHRPGVVTKAGLILFGNDDKMLLVKNIQLED-GKMILASNFFKG-AASSVLELTEAELVTAEAVRSVWQRILPKVLEVEDSTDFFKSGAASVDVVRLVEEVKELCD-GLELENEDVYMASTFGDFIQLLVRKLRGDDEEGECSIDYVEMAVNKRTVRMPHQLFIGGEFVDAEGAKTSETINPTDGSVICQVSLAQVTDVDKAVAAAKDAFENGRWGKISARDRGRLMYRLADLMEQHQEELATIEALDAGAVYTLALKTHVGMSIQTFRYFAGWCDKIQGSTIPINQARPNRNLTLTRKEPVGVCGIIIPWNYPLMMLSWKTAACLAAGNTVVIKPAQVTPLTALKFAELTLKAGIPKGVVNVLPGSGSLVGQRLSDHPDVRKIGFTGSTEVGKHIMKSCAISNVKKVSLELGGKSPLIIFADCDLNKAVQMGMSSVFFNKGENCIAAGRLFVEDSIHDEFVRRVVEEVRKMKVGNPLDRDTDHGPQNHHAHLVKLMEYCQHGVKEGATLVCGGNQVPRPGFFFEPTVFTDVEDHMFIAKEESFGPVMIISRFADGDLDAVLSRANATEFGLASGVFTRDINKALYVSDKLQAGTVFVNTYNKTDVAAPFGGFKQSGFGKDLGEAALNEYLRVKTVTFEY 902 HSP 2 Score: 72.7886 bits (177), Expect = 3.430e-12 Identity = 31/66 (46.97%), Postives = 49/66 (74.24%), Query Frame = 1
Query: 115 MKIAIIGQSIFGAQVYKELKNEGHDIVGVFTIPDRNGRSDPLGIFYWE*GFTTLLMTSKKSQGRPL 312
MKIA+IGQS+FG +VY L+ EGH++VGVFT+PD++G++DPLG+ + G + +++G+ L
Sbjct: 1 MKIAVIGQSLFGQEVYCHLRKEGHEVVGVFTVPDKDGKADPLGLEAEKDGVPVFKYSRWRAKGQAL 66
BLAST of 10-formyltetrahydrofolate dehydrogenase vs. Ensembl Human
Match: ALDH1L1 (aldehyde dehydrogenase 1 family member L1 [Source:HGNC Symbol;Acc:HGNC:3978]) HSP 1 Score: 1063.52 bits (2749), Expect = 0.000e+0 Identity = 516/863 (59.79%), Postives = 668/863 (77.40%), Query Frame = 3
Query: 438 AMEAIDLGTKVFKIPKWRVNNQIIKEVFEEYRSINAELNVLAFCTQFIPMEVINAPKHRSIIYHPSLLPKHRGASAINWTLINGDLKGGLTIFWADDGLDTGPVLLQRECDVHINDTVDSLYSRFMMPEGIKAMVEAVRQIESGRAPAIAQYHPDHSYDQMVKKSTAEINWNQSGLSLHNFIRGHDKVPGAWSWINGQKVTFYGSQLWYHDVVHDGPSLAIQGLSDPAVLHNHGLLIRGSDNQWINIAQLKFEDTGKTVQASKYGKGDEITTMADLSEDERAMEIPLMKIWKSILMGS-DIEPESDFFKLGGTSMDVTRIIEQIK--CNFNVELKIDHIYLYSTFDTLFKWIVLRKRGGGSQKKLHYDAVIINANKMTFPIPHQIFINNEFVNSESGKEYDSKNPSDESVICRVSYSSXXXXXXXXXXXXXXFEFGEWGKMSARDRGRILYKLADLMEEHAEELATLESLDSGAVYTLALKTHIGMSIETFRYFAGWCDKIQGSTIPISNARPNKNLSFTKKEPIGVCGIITPWNYPLMMLAWKVAACLAAGNTVVLKPAQVTPLASLKFCELSVEAGFPPGVINVLPGSGAIAGTAISEHPDIRKLGFTGSTAIGQTIMSSCAKSNLKKCSLELGGKSPLIIFSDCDMDKAVKSACSSVFFNKGENCIAAGRIFVDVRIHDVFLKLVVEDVKKMKIGDPLDRSVDHGPQNHEIHLLKLLEFCDIGVKEGAKLVFGGKRCDRKGYFMEPTIFTSVTDDMYIAREESFGPIMIISKFY--DIDEVIVRANKTEYGLASGVFTNDISKALRVADAIDAGTVFINTYNKTDVAAPFGGFKQSGFGKDLGQEALNEYLKTKTVTVEY 3011
+EA G VFK +WR Q + +V +Y+++ AELNVL FC+QFIPME+I+AP+H SIIYHPSLLP+HRGASAINWTLI+GD KGG +IFWADDGLDTG +LLQ+EC+V +DTV +LY+RF+ PEGIK MV+AVR I G+AP + Q +Y+ + KK TA+INW+Q ++HN+IRG+DKVPGAW+ QK+TF+ S L +V +G +L I G P V+ GL++ G+D++ + + ++ ED GK + AS + KG +++ +L+E E + +W+ IL ++E +DFFK G S+DV R++E++K C+ +EL+ + +Y+ STF + +V + RG + + D V + NK T +PHQ+FI EFV++E K ++ NP+D SVIC+VS + DVD AV AAK+AFE G WGK+SARDRGR++Y+LADLME+H EELAT+E+LD+GAVYTLALKTH+GMSI+TFRYFAGWCDKIQGSTIPI+ ARPN+NL+ T+KEP+GVCGII PWNYPLMML+WK AACLAAGNTVV+KPAQVTPL +LKF EL+++AG P GV+NVLPGSG++ G +S+HPD+RK+GFTGST +G+ IM SCA SN+KK SLELGGKSPLIIF+DCD++KAV+ SSVFFNKGENCIAAGR+FV+ IHD F++ VVE+V+KMK+G+PLDR DHGPQNH HL+KL+E+C GVKEGA LV GG + R G+F EPT+FT V D M+IA+EESFGP+MIIS+F D+D V+ RAN TE+GLASGVFT DI+KAL V+D + AGTVF+NTYNKTDVAAPFGGFKQSGFGKDLG+ ALNEYL+ KTVT EY
Sbjct: 43 GLEAEKDGVPVFKYSRWRAKGQALPDVVAKYQALGAELNVLPFCSQFIPMEIISAPRHGSIIYHPSLLPRHRGASAINWTLIHGDKKGGFSIFWADDGLDTGDLLLQKECEVLPDDTVSTLYNRFLFPEGIKGMVQAVRLIAEGKAPRLPQPEEGATYEGIQKKETAKINWDQPAEAIHNWIRGNDKVPGAWTEACEQKLTFFNSTLNTSGLVPEGDALPIPGAHRPGVVTKAGLILFGNDDKMLLVKNIQLED-GKMILASNFFKG-AASSVLELTEAELVTAEAVRSVWQRILPKVLEVEDSTDFFKSGAASVDVVRLVEEVKELCD-GLELENEDVYMASTFGDFIQLLVRKLRGDDEEGECSIDYVEMAVNKRTVRMPHQLFIGGEFVDAEGAKTSETINPTDGSVICQVSLAQVTDVDKAVAAAKDAFENGRWGKISARDRGRLMYRLADLMEQHQEELATIEALDAGAVYTLALKTHVGMSIQTFRYFAGWCDKIQGSTIPINQARPNRNLTLTRKEPVGVCGIIIPWNYPLMMLSWKTAACLAAGNTVVIKPAQVTPLTALKFAELTLKAGIPKGVVNVLPGSGSLVGQRLSDHPDVRKIGFTGSTEVGKHIMKSCAISNVKKVSLELGGKSPLIIFADCDLNKAVQMGMSSVFFNKGENCIAAGRLFVEDSIHDEFVRRVVEEVRKMKVGNPLDRDTDHGPQNHHAHLVKLMEYCQHGVKEGATLVCGGNQVPRPGFFFEPTVFTDVEDHMFIAKEESFGPVMIISRFADGDLDAVLSRANATEFGLASGVFTRDINKALYVSDKLQAGTVFVNTYNKTDVAAPFGGFKQSGFGKDLGEAALNEYLRVKTVTFEY 902 HSP 2 Score: 72.7886 bits (177), Expect = 3.430e-12 Identity = 31/66 (46.97%), Postives = 49/66 (74.24%), Query Frame = 1
Query: 115 MKIAIIGQSIFGAQVYKELKNEGHDIVGVFTIPDRNGRSDPLGIFYWE*GFTTLLMTSKKSQGRPL 312
MKIA+IGQS+FG +VY L+ EGH++VGVFT+PD++G++DPLG+ + G + +++G+ L
Sbjct: 1 MKIAVIGQSLFGQEVYCHLRKEGHEVVGVFTVPDKDGKADPLGLEAEKDGVPVFKYSRWRAKGQAL 66
BLAST of 10-formyltetrahydrofolate dehydrogenase vs. Ensembl Celegans
Match: alh-3 (10-formyltetrahydrofolate dehydrogenase [Source:UniProtKB/TrEMBL;Acc:G5ECV9]) HSP 1 Score: 1003.05 bits (2592), Expect = 0.000e+0 Identity = 499/870 (57.36%), Postives = 641/870 (73.68%), Query Frame = 3
Query: 438 AMEAIDLGTKVFKIPKWRVNN------QIIKEVFEEYRSINAELNVLAFCTQFIPMEVINAPKHRSIIYHPSLLPKHRGASAINWTLINGDLKGGLTIFWADDGLDTGPVLLQRECDVHINDTVDSLYSRFMMPEGIKAMVEAVRQIESGRAPAIAQYHPDHSYDQMV--KKSTAEINWNQSGLSLHNFIRGHDKVPGAWSWINGQKVTFYGSQLWY-HDVVHDGPSLAIQGLSDPAVL-HNHGLLIRGSDNQWINIAQLKFEDTGKTVQASKYGKGDEITTMADLSEDERAMEIPLMKIWKSILMGSDIEPESDFFKLGGTSMDVTRIIEQIKCNFNVELKIDHIYLYSTFDTLFKWIVLRKRGGGSQKKLHYDAVIINANKMTFPIPHQIFINNEFVNSESGKEYDSKNPSDESVICRVSYSSXXXXXXXXXXXXXXFEFGEWGKMSARDRGRILYKLADLMEEHAEELATLESLDSGAVYTLALKTHIGMSIETFRYFAGWCDKIQGSTIPISNARPNKNLSFTKKEPIGVCGIITPWNYPLMMLAWKVAACLAAGNTVVLKPAQVTPLASLKFCELSVEAGFPPGVINVLPGSGAIAGTAISEHPDIRKLGFTGSTAIGQTIMSSCAKSNLKKCSLELGGKSPLIIFSDCDMDKAVKSACSSVFFNKGENCIAAGRIFVDVRIHDVFLKLVVEDVKKMKIGDPLDRSVDHGPQNHEIHLLKLLEFCDIGVKEGAKLVFGGKRCDRKGYFMEPTIFTSVTDDMYIAREESFGPIMIISKF--YDIDEVIVRANKTEYGLASGVFTNDISKALRVADAIDAGTVFINTYNKTDVAAPFGGFKQSGFGKDLGQEALNEYLKTKTVTVEY 3011
A+EA G V K +WR N + + E+ E Y+S AELNVL FCTQFIP+E+ AP +SIIYHPS+LPKHRGASAINWTLI GD + GL+IFWADDGLDTGP+LLQ++C V NDT+++LY RF+ P G+ A+ E+V I +G+AP I Q SY+ + K A+I+W+++ LHNFIRG+DKVPGAW+ +NG+KV+F+GS+LW + D + + + VL + GLL+ GSD +W+ + +K KTV ASKYG+G + L+++E++ L KIW IL + + ++DFF+ G +S DVTR++E+IK N EL+ IY T ++ RG G + YD +++N N M PH FI+ +FV S G+ + + NP+ E IC + ++ DVD AV+AAK+AFE GEW +MSAR+RG+ LYKLA+LMEEH EELATLESLD+GAVYTLALKTH+GMSI+ +RYFAGWCDKIQG TIPISNARPNKNL T +EPIGV G+ITPWNYPLMML+WK+AACLAAGNTVV KPAQVTPL +LKF ELSV AG PPGVIN++ GSG++ G ++ HPD+RK+GFTGST IG T+M SCAKSN+KK SLELGGKSPLIIF+D D++KAVK AC +VFFNKGENCIAAGR+F+ IHD F+K +VE+ K+ +IGDPLDRS HGPQNH HL KL+E+ + V GAK+ GGKR +R+G + PTI +++ D+ + A EESFGPIM +S F DI++V+ RAN TE+GLA+GVFT D SK+LRVA+A+ AGTVF+NTY KTDVAAPFGGFKQSGFGKD+G+EALNEYL TKT+T+EY
Sbjct: 43 AVEAAKDGVPVQKPSRWRKKNPETGKFETLPEMLELYKSFGAELNVLPFCTQFIPLEITEAPAKKSIIYHPSILPKHRGASAINWTLIEGDEEAGLSIFWADDGLDTGPILLQKKCKVEENDTLNTLYKRFLYPAGVAAVAESVELIATGKAPRIVQPEEGASYEPYITTKPELAQIDWSKTQRQLHNFIRGNDKVPGAWAVLNGEKVSFFGSKLWKPKKLPDDAVEVFVSEVPGGKVLVEDRGLLLPGSDGRWVIVDTVKI--GTKTVPASKYGQGADQVQELVLTDEEKSTVAKLKKIWTGILK-TQVSSDTDFFESGASSADVTRLVEEIKFNTGAELESGQIYAGPTLGENIDIVIRNLRGEGGIS-VTYDPIVLNVNNMELKFPHDQFIDGKFVGSSDGRTFKTINPATEKPICELPLATVADVDRAVRAAKKAFERGEWRQMSARERGKRLYKLAELMEEHKEELATLESLDAGAVYTLALKTHVGMSIDVWRYFAGWCDKIQGKTIPISNARPNKNLCLTLREPIGVVGLITPWNYPLMMLSWKMAACLAAGNTVVHKPAQVTPLTALKFAELSVLAGIPPGVINIVTGSGSLVGNRLTAHPDVRKIGFTGSTEIGATVMESCAKSNIKKVSLELGGKSPLIIFADADLEKAVKQACGAVFFNKGENCIAAGRVFIAKSIHDDFVKKLVEEAKQYQIGDPLDRSTAHGPQNHLAHLNKLVEYVEKAVAGGAKVEVGGKRLEREGLYFPPTILSNIDDENFAASEESFGPIMCVSSFDDDDIEDVLRRANDTEFGLAAGVFTRDSSKSLRVAEALHAGTVFVNTYQKTDVAAPFGGFKQSGFGKDMGEEALNEYLVTKTITIEY 908 HSP 2 Score: 69.707 bits (169), Expect = 1.177e-11 Identity = 31/44 (70.45%), Postives = 35/44 (79.55%), Query Frame = 1
Query: 115 MKIAIIGQSIFGAQVYKELKNEGHDIVGVFTIPDRNGRSDPLGI 246
MKIAIIGQS FG VYKEL+ GH+IV VFTIPD+NGR D L +
Sbjct: 1 MKIAIIGQSAFGVDVYKELRKNGHEIVVVFTIPDKNGREDLLAV 44
BLAST of 10-formyltetrahydrofolate dehydrogenase vs. Ensembl Celegans
Match: alh-2 (ALdehyde deHydrogenase [Source:UniProtKB/TrEMBL;Acc:Q9TXM0]) HSP 1 Score: 462.996 bits (1190), Expect = 1.765e-151 Identity = 238/477 (49.90%), Postives = 340/477 (71.28%), Query Frame = 3
Query: 1581 IFINNEFVNSESGKEYDSKNPSDESVICRVSYSSXXXXXXXXXXXXXXFEFG-EWGKMSARDRGRILYKLADLMEEHAEELATLESLDSGAVYTLALKTHIGMSIETFRYFAGWCDKIQGSTIPISNARPNKNLSFTKKEPIGVCGIITPWNYPLMMLAWKVAACLAAGNTVVLKPAQVTPLASLKFCELSVEAGFPPGVINVLPGSGAIAGTAISEHPDIRKLGFTGSTAIGQTIMSSCAKSNLKKCSLELGGKSPLIIFSDCDMDKAVKSACSSVFFNKGENCIAAGRIFVDVRIHDVFLKLVVEDVKKMKIGDPLDRSVDHGPQNHEIHLLKLLEFCDIGVKEGAKLVFGGKRCDRKGYFMEPTIFTSVTDDMYIAREESFGPIMIISKFYDIDEVIVRANKTEYGLASGVFTNDISKALRVADAIDAGTVFINTYNKTDVAAPFGGFKQSGFGKDLGQEALNEYLKTKTVTVE 3008
+FINNEFV+++SGK ++ NP++ ++ +V+ ++ DVDIAV+AAK+AF+ G EW +M A RG +L +LADLME LA+LESLD+G Y A + +SI+TFRY+AG+ DK G TIP+ ++T+ EP+GVCG I PWN+PL+M AWK+A LA GNTVV+K A TPL++L L EA FP GV+N++PG G AG AI+ H D+ K+ FTGST +G+TIM + A+SN+KK +LELGGKSP I+F+D D+++AV+ + ++FFN+G+ C A R FV+ +I+D F+ E V+K IGDP D + GPQ E + ++++ + G KEGA+LV GG + +GYF++PTIF +V D M IA+EE FGP+MI+ +F ++E+I +AN T YGLA+GV TND++KAL+VA+ I AG+V++N Y+ D AAPFGGFKQSG G++LG+ L Y + KTVT++
Sbjct: 36 LFINNEFVDAKSGKTFEFVNPANGKLLAKVAEGNRDDVDIAVEAAKKAFKIGSEWRRMDASHRGVLLNRLADLMERDRVILASLESLDNGKPYKEAYNIDLPISIKTFRYYAGYADKNHGKTIPVGG----DYFTYTRHEPVGVCGQIIPWNFPLLMQAWKLAPALAMGNTVVMKVAVKTPLSALHVASLIKEAQFPEGVVNIIPGRGTDAGEAIASHMDVDKVAFTGSTEVGKTIMKAAAESNVKKVTLELGGKSPNIVFADADLEEAVRQSHHALFFNQGQCCSAGSRTFVEGKIYDEFVAKAKELVEKTVIGDPFDENTTQGPQIDESQVETIMKYIESGKKEGAQLVTGGVKHGDQGYFVKPTIFANVNDQMKIAQEEIFGPVMIVIRFDSMEELIEKANNTIYGLAAGVVTNDLNKALQVANTIRAGSVWVNCYDVFDPAAPFGGFKQSGIGRELGEYGLAAYTEVKTVTIK 508
BLAST of 10-formyltetrahydrofolate dehydrogenase vs. Ensembl Celegans
Match: alh-1 (ALdehyde deHydrogenase [Source:UniProtKB/TrEMBL;Acc:Q20780]) HSP 1 Score: 457.988 bits (1177), Expect = 1.253e-149 Identity = 236/477 (49.48%), Postives = 327/477 (68.55%), Query Frame = 3
Query: 1581 IFINNEFVNSESGKEYDSKNPSDESVICRVSYSSXXXXXXXXXXXXXXFEFG-EWGKMSARDRGRILYKLADLMEEHAEELATLESLDSGAVYTLALKTHIGMSIETFRYFAGWCDKIQGSTIPISNARPNKNLSFTKKEPIGVCGIITPWNYPLMMLAWKVAACLAAGNTVVLKPAQVTPLASLKFCELSVEAGFPPGVINVLPGSGAIAGTAISEHPDIRKLGFTGSTAIGQTIMSSCAKSNLKKCSLELGGKSPLIIFSDCDMDKAVKSACSSVFFNKGENCIAAGRIFVDVRIHDVFLKLVVEDVKKMKIGDPLDRSVDHGPQNHEIHLLKLLEFCDIGVKEGAKLVFGGKRCDRKGYFMEPTIFTSVTDDMYIAREESFGPIMIISKFYDIDEVIVRANKTEYGLASGVFTNDISKALRVADAIDAGTVFINTYNKTDVAAPFGGFKQSGFGKDLGQEALNEYLKTKTVTVE 3008
IFINNEFV ++SGK +++ NP++ V+ +V+ K DV+IAVKAA+ AF G EW +M A RG +L +LADLME LA+LESLD+G Y +A + +SI+T RY+AGW DK G TIPI ++T+ EP+GVCG I PWN+PL+M AWK+ LA GNTVV+K A+ TPL++L L+ EAGFP GV+N++PG G AG AIS H D+ K+ FTGST +G+ +M + A+SN+KK +LELGGKSP IIF+D D++ +V A +FFN+G+ C A R FV+ +I+D F+ E +K IGDP D GPQ + +L++ G K+GA+LV GG + +G+F++PTIF +V D M IA+EE FGP+M I +F ++E++ +AN T YGLA+GV T DI KAL +A+A AG+V++N Y+ D AAPFGGFKQSG G++LG+ L Y + KTVT++
Sbjct: 32 IFINNEFVPAKSGKTFETINPANGKVLAQVAEGDKTDVNIAVKAAQNAFRIGSEWRRMDASQRGVLLNRLADLMERDRVILASLESLDNGKPYAVAYNADLPLSIKTLRYYAGWADKNHGKTIPIEG----DYFTYTRHEPVGVCGQIIPWNFPLLMQAWKLGPALAMGNTVVMKVAEQTPLSALHVAALTKEAGFPDGVVNIIPGYGHTAGQAISSHMDVDKVAFTGSTEVGRLVMKAAAESNVKKVTLELGGKSPNIIFADADLNDSVHQANHGLFFNQGQCCCAGSRTFVEGKIYDDFVARSKELAEKAVIGDPFDLKTTQGPQVDGKQVETILKYIAAGKKDGAQLVTGGAKHGDQGHFVKPTIFANVKDQMTIAQEEIFGPVMTIIRFDTMEELVEKANNTIYGLAAGVMTKDIDKALHIANATRAGSVWVNCYDVFDAAAPFGGFKQSGIGRELGEYGLEAYTEVKTVTIK 504
BLAST of 10-formyltetrahydrofolate dehydrogenase vs. Ensembl Celegans
Match: alh-1 (ALdehyde deHydrogenase [Source:UniProtKB/TrEMBL;Acc:Q20780]) HSP 1 Score: 457.988 bits (1177), Expect = 1.253e-149 Identity = 236/477 (49.48%), Postives = 327/477 (68.55%), Query Frame = 3
Query: 1581 IFINNEFVNSESGKEYDSKNPSDESVICRVSYSSXXXXXXXXXXXXXXFEFG-EWGKMSARDRGRILYKLADLMEEHAEELATLESLDSGAVYTLALKTHIGMSIETFRYFAGWCDKIQGSTIPISNARPNKNLSFTKKEPIGVCGIITPWNYPLMMLAWKVAACLAAGNTVVLKPAQVTPLASLKFCELSVEAGFPPGVINVLPGSGAIAGTAISEHPDIRKLGFTGSTAIGQTIMSSCAKSNLKKCSLELGGKSPLIIFSDCDMDKAVKSACSSVFFNKGENCIAAGRIFVDVRIHDVFLKLVVEDVKKMKIGDPLDRSVDHGPQNHEIHLLKLLEFCDIGVKEGAKLVFGGKRCDRKGYFMEPTIFTSVTDDMYIAREESFGPIMIISKFYDIDEVIVRANKTEYGLASGVFTNDISKALRVADAIDAGTVFINTYNKTDVAAPFGGFKQSGFGKDLGQEALNEYLKTKTVTVE 3008
IFINNEFV ++SGK +++ NP++ V+ +V+ K DV+IAVKAA+ AF G EW +M A RG +L +LADLME LA+LESLD+G Y +A + +SI+T RY+AGW DK G TIPI ++T+ EP+GVCG I PWN+PL+M AWK+ LA GNTVV+K A+ TPL++L L+ EAGFP GV+N++PG G AG AIS H D+ K+ FTGST +G+ +M + A+SN+KK +LELGGKSP IIF+D D++ +V A +FFN+G+ C A R FV+ +I+D F+ E +K IGDP D GPQ + +L++ G K+GA+LV GG + +G+F++PTIF +V D M IA+EE FGP+M I +F ++E++ +AN T YGLA+GV T DI KAL +A+A AG+V++N Y+ D AAPFGGFKQSG G++LG+ L Y + KTVT++
Sbjct: 32 IFINNEFVPAKSGKTFETINPANGKVLAQVAEGDKTDVNIAVKAAQNAFRIGSEWRRMDASQRGVLLNRLADLMERDRVILASLESLDNGKPYAVAYNADLPLSIKTLRYYAGWADKNHGKTIPIEG----DYFTYTRHEPVGVCGQIIPWNFPLLMQAWKLGPALAMGNTVVMKVAEQTPLSALHVAALTKEAGFPDGVVNIIPGYGHTAGQAISSHMDVDKVAFTGSTEVGRLVMKAAAESNVKKVTLELGGKSPNIIFADADLNDSVHQANHGLFFNQGQCCCAGSRTFVEGKIYDDFVARSKELAEKAVIGDPFDLKTTQGPQVDGKQVETILKYIAAGKKDGAQLVTGGAKHGDQGHFVKPTIFANVKDQMTIAQEEIFGPVMTIIRFDTMEELVEKANNTIYGLAAGVMTKDIDKALHIANATRAGSVWVNCYDVFDAAAPFGGFKQSGIGRELGEYGLEAYTEVKTVTIK 504
BLAST of 10-formyltetrahydrofolate dehydrogenase vs. Ensembl Celegans
Match: alh-1 (ALdehyde deHydrogenase [Source:UniProtKB/TrEMBL;Acc:Q20780]) HSP 1 Score: 424.091 bits (1089), Expect = 7.773e-138 Identity = 207/420 (49.29%), Postives = 285/420 (67.86%), Query Frame = 3
Query: 1749 MSARDRGRILYKLADLMEEHAEELATLESLDSGAVYTLALKTHIGMSIETFRYFAGWCDKIQGSTIPISNARPNKNLSFTKKEPIGVCGIITPWNYPLMMLAWKVAACLAAGNTVVLKPAQVTPLASLKFCELSVEAGFPPGVINVLPGSGAIAGTAISEHPDIRKLGFTGSTAIGQTIMSSCAKSNLKKCSLELGGKSPLIIFSDCDMDKAVKSACSSVFFNKGENCIAAGRIFVDVRIHDVFLKLVVEDVKKMKIGDPLDRSVDHGPQNHEIHLLKLLEFCDIGVKEGAKLVFGGKRCDRKGYFMEPTIFTSVTDDMYIAREESFGPIMIISKFYDIDEVIVRANKTEYGLASGVFTNDISKALRVADAIDAGTVFINTYNKTDVAAPFGGFKQSGFGKDLGQEALNEYLKTKTVTVE 3008
M A RG +L +LADLME LA+LESLD+G Y +A + +SI+T RY+AGW DK G TIPI ++T+ EP+GVCG I PWN+PL+M AWK+ LA GNTVV+K A+ TPL++L L+ EAGFP GV+N++PG G AG AIS H D+ K+ FTGST +G+ +M + A+SN+KK +LELGGKSP IIF+D D++ +V A +FFN+G+ C A R FV+ +I+D F+ E +K IGDP D GPQ + +L++ G K+GA+LV GG + +G+F++PTIF +V D M IA+EE FGP+M I +F ++E++ +AN T YGLA+GV T DI KAL +A+A AG+V++N Y+ D AAPFGGFKQSG G++LG+ L Y + KTVT++
Sbjct: 1 MDASQRGVLLNRLADLMERDRVILASLESLDNGKPYAVAYNADLPLSIKTLRYYAGWADKNHGKTIPIEG----DYFTYTRHEPVGVCGQIIPWNFPLLMQAWKLGPALAMGNTVVMKVAEQTPLSALHVAALTKEAGFPDGVVNIIPGYGHTAGQAISSHMDVDKVAFTGSTEVGRLVMKAAAESNVKKVTLELGGKSPNIIFADADLNDSVHQANHGLFFNQGQCCCAGSRTFVEGKIYDDFVARSKELAEKAVIGDPFDLKTTQGPQVDGKQVETILKYIAAGKKDGAQLVTGGAKHGDQGHFVKPTIFANVKDQMTIAQEEIFGPVMTIIRFDTMEELVEKANNTIYGLAAGVMTKDIDKALHIANATRAGSVWVNCYDVFDAAAPFGGFKQSGIGRELGEYGLEAYTEVKTVTIK 416
BLAST of 10-formyltetrahydrofolate dehydrogenase vs. Ensembl Fly
Match: CG8665 (gene:FBgn0032945 transcript:FBtr0081517) HSP 1 Score: 999.579 bits (2583), Expect = 0.000e+0 Identity = 503/860 (58.49%), Postives = 637/860 (74.07%), Query Frame = 3
Query: 468 VFKIPKWRVNNQIIKEVFEEYRSINAELNVLAFCTQFIPMEVINAPKHRSIIYHPSLLPKHRGASAINWTLINGDLKGGLTIFWADDGLDTGPVLLQRECDVHINDTVDSLYSRFMMPEGIKAMVEAVRQIESGRAPAIAQYHPDHSYD-QMVKKSTAEINWNQSGLSLHNFIRGHDKVPGAWSWI---NG--QKVTFYGSQLWYHDVVHDGPSLAIQGLSDPAVLHNHGLLIRGSDNQWINIAQLKFEDTGKTVQASKYGKGDEITTMADLSEDERAMEIPLMKIWKSILMGSDIEPESDFFKLGGTSMDVTRIIEQIKCNFNVELKIDHIYLYSTFDTLFKWIV--LRKRGGG-SQKKLHYDAVIINANKMTFPIPHQIFINNEFVNSESGKEYDSKNPSDESVICRVSYSSXXXXXXXXXXXXXXFEFGEWGKMSARDRGRILYKLADLMEEHAEELATLESLDSGAVYTLALKTHIGMSIETFRYFAGWCDKIQGSTIPISNARPNKNLSFTKKEPIGVCGIITPWNYPLMMLAWKVAACLAAGNTVVLKPAQVTPLASLKFCELSVEAGFPPGVINVLPGSGAIAGTAISEHPDIRKLGFTGSTAIGQTIMSSCAKSNLKKCSLELGGKSPLIIFSDCDMDKAVKSACSSVFFNKGENCIAAGRIFVDVRIHDVFLKLVVEDVKKMKIGDPLDRSVDHGPQNHEIHLLKLLEFCDIGVKEGAKLVFGGKRC-DRKGYFMEPTIFTSVTDDMYIAREESFGPIMIISKF--YDIDEVIVRANKTEYGLASGVFTNDISKALRVADAIDAGTVFINTYNKTDVAAPFGGFKQSGFGKDLGQEALNEYLKTKTVTVEY 3011
VFK WR + EV E+Y+S+ A LNVL FC+QFIPMEVIN SI YHPS+LP+HRGASAI+WTLI GD G +IFWADDGLDTGP+LL R+ +V DT+D++Y RF+ PEG+KAM AV + SG AP I Q +YD M K IN + + NF+RG D VPGA + + NG +++ +G+ L+ V +G L ++GL+ A +H+ GLLI G+D ++NI ++K K + AS++ K E ++ D SEDE L IWK+IL D+E +DFF G SMDV R++E++K F+V L+ + +++ F+ F +V LR+ G ++L ++A + ANK +P Q+FIN EFV++E+ + + NP++E V+C+V+ +S DVD AV+AA AF +G W +++ R RG+++ LADLME + EELAT+ES+DSGAVYTLALKTH+GMSIE +RYFAGWCDKIQG+TIP++ ARPN L+FT+KEPIGVCG+ITPWNYPLMML+WK+AAC+AAGNT ++KPAQ PL +LKF EL+V AGFPPGVINVLPG G+ AG A+++H +RKLGFTGST IG+ IM SCA SNLKKCSLELGGKSPLIIF+DCDMDKAVK SSVFFNKGENCIAAGR+FV+ RIHD F++ V++D++ M IGDPLDRS HGPQNH+ H KLLEFC GV EGAKLV+GG R + KGYF PT+FT+VTDDM+IA+EESFGPIMIISKF DID ++ RAN+TEYGLASGVFT DI KAL AD I+AGTVF+N YNKTDVAAPFGGFKQSG+GKDLGQEALNEYLKTK VTVEY
Sbjct: 58 VFKFACWRRKGVALPEVLEQYKSVGATLNVLPFCSQFIPMEVINGALLGSICYHPSILPRHRGASAISWTLIEGDEVAGFSIFWADDGLDTGPLLLTRQTNVESTDTLDTIYKRFLYPEGVKAMGVAVDMVASGTAPKIIQPEVGATYDPAMFKTENQVINLQATAEKIWNFVRGLDSVPGAIATVLHGNGTEEQIRLFGAHLYSAGPVSNGKVLRLRGLTKTAWIHSGGLLIEGTDGAFVNIRRIK--RGTKVISASEWFKQAEDQSITDFSEDELVKRSLLAGIWKAILK-EDVESSTDFFASGAGSMDVVRLVEEVKEAFDVPLQNEQVFMAPVFEEFFSLLVRFLRQGSAGFGNQQLDFEAFTLKANKREIRVPTQLFINGEFVDAEAQRTLEIVNPTNEEVLCKVACASATDVDKAVRAAHSAF-YGSWRQITPRQRGQLMLNLADLMERNKEELATIESVDSGAVYTLALKTHVGMSIEAWRYFAGWCDKIQGNTIPVNPARPNNVLTFTRKEPIGVCGLITPWNYPLMMLSWKMAACIAAGNTCLIKPAQTCPLTALKFAELTVRAGFPPGVINVLPGKGSDAGQAVADHELVRKLGFTGSTPIGKHIMKSCADSNLKKCSLELGGKSPLIIFADCDMDKAVKHGMSSVFFNKGENCIAAGRLFVEDRIHDEFIRRVLKDLRTMTIGDPLDRSTAHGPQNHKAHFDKLLEFCRRGVDEGAKLVYGGCRVPNLKGYFFTPTVFTNVTDDMFIAQEESFGPIMIISKFNGSDIDSLMQRANRTEYGLASGVFTKDIGKALNFADRIEAGTVFVNVYNKTDVAAPFGGFKQSGYGKDLGQEALNEYLKTKCVTVEY 913
BLAST of 10-formyltetrahydrofolate dehydrogenase vs. Ensembl Fly
Match: Aldh (gene:FBgn0012036 transcript:FBtr0332597) HSP 1 Score: 446.817 bits (1148), Expect = 4.063e-145 Identity = 234/497 (47.08%), Postives = 328/497 (66.00%), Query Frame = 3
Query: 1548 ANKMTFPIPHQ--------IFINNEFVNSESGKEYDSKNPSDESVICRVSYSSXXXXXXXXXXXXXXFEFGE-WGKMSARDRGRILYKLADLMEEHAEELATLESLDSGAVYTLALKTHIGMSIETFRYFAGWCDKIQGSTIPISNARPNKNLSFTKKEPIGVCGIITPWNYPLMMLAWKVAACLAAGNTVVLKPAQVTPLASLKFCELSVEAGFPPGVINVLPGSGAIAGTAISEHPDIRKLGFTGSTAIGQTIMSSCAKSNLKKCSLELGGKSPLIIFSDCDMDKAVKSACSSVFFNKGENCIAAGRIFVDVRIHDVFLKLVVEDVKKMKIGDPLDRSVDHGPQNHEIHLLKLLEFCDIGVKEGAKLVFGGKRCD-RKGYFMEPTIFTSVTDDMYIAREESFGPIMIISKFYDIDEVIVRANKTEYGLASGVFTNDISKALRVADAIDAGTVFINTYNKTDVAAPFGGFKQSGFGKDLGQEALNEYLKTKTVTVE 3008
AN + P P +FINNE+ S+SGK +++ NP+ VI + + K+D+DIAV+AA+ AF+ G W +M A +RGR+LY+LADLME LA+LE+LD+G Y+++ + +I+ RYFAGW DK G TIP+ ++T+ EP+GVCG I PWN+P++M+AWK+ LA GNT+VLKPA+ T L +L +L EAGFP GV+NV+PG G AG A++ H D+ K+ FTGST +G+ I + +NLK+ +LELGGKSP II SD DMD AV++A +FFN G+ C A R FV+ +I+D F++ E KK +G+P D + + GPQ +E + K+L G K+GAKLV GG R + GYF++PT+F V DDM IAREE FGP+ + +F +DEVI RAN +EYGLA+ VFT D+ KA + + AGTV++NTYN APFGG+K SG G++ G+ AL+ Y + K+V V+
Sbjct: 23 ANYSSLPQPQTTPDILYTGVFINNEWHKSKSGKIFETINPTTAEVIAEIQCADKEDIDIAVQAARNAFKLGSPWRRMDASERGRLLYRLADLMERDQVYLASLETLDNGKPYSMSYNVDLPTAIKNLRYFAGWADKNHGKTIPMDG----DFFTYTRHEPVGVCGQIIPWNFPILMMAWKLGPALATGNTIVLKPAEQTSLTALYIAQLVKEAGFPEGVVNVVPGFGT-AGAALANHCDVDKVAFTGSTDVGKLIQLASGNTNLKRVTLELGGKSPNIILSDTDMDYAVETAHFGLFFNMGQCCCAGSRTFVEDKIYDEFVERSAERAKKRTVGNPFDLNTEQGPQVNEEQMEKILGMIKTGKKQGAKLVAGGSRPEGLPGYFVQPTVFADVQDDMTIAREEIFGPVQQLIRFKKLDEVIERANNSEYGLAAAVFTKDLDKANYIVGGLRAGTVWVNTYNVLAAQAPFGGYKMSGHGRENGEYALSNYTEVKSVIVK 514
BLAST of 10-formyltetrahydrofolate dehydrogenase vs. Ensembl Fly
Match: Aldh (gene:FBgn0012036 transcript:FBtr0079806) HSP 1 Score: 446.817 bits (1148), Expect = 4.063e-145 Identity = 234/497 (47.08%), Postives = 328/497 (66.00%), Query Frame = 3
Query: 1548 ANKMTFPIPHQ--------IFINNEFVNSESGKEYDSKNPSDESVICRVSYSSXXXXXXXXXXXXXXFEFGE-WGKMSARDRGRILYKLADLMEEHAEELATLESLDSGAVYTLALKTHIGMSIETFRYFAGWCDKIQGSTIPISNARPNKNLSFTKKEPIGVCGIITPWNYPLMMLAWKVAACLAAGNTVVLKPAQVTPLASLKFCELSVEAGFPPGVINVLPGSGAIAGTAISEHPDIRKLGFTGSTAIGQTIMSSCAKSNLKKCSLELGGKSPLIIFSDCDMDKAVKSACSSVFFNKGENCIAAGRIFVDVRIHDVFLKLVVEDVKKMKIGDPLDRSVDHGPQNHEIHLLKLLEFCDIGVKEGAKLVFGGKRCD-RKGYFMEPTIFTSVTDDMYIAREESFGPIMIISKFYDIDEVIVRANKTEYGLASGVFTNDISKALRVADAIDAGTVFINTYNKTDVAAPFGGFKQSGFGKDLGQEALNEYLKTKTVTVE 3008
AN + P P +FINNE+ S+SGK +++ NP+ VI + + K+D+DIAV+AA+ AF+ G W +M A +RGR+LY+LADLME LA+LE+LD+G Y+++ + +I+ RYFAGW DK G TIP+ ++T+ EP+GVCG I PWN+P++M+AWK+ LA GNT+VLKPA+ T L +L +L EAGFP GV+NV+PG G AG A++ H D+ K+ FTGST +G+ I + +NLK+ +LELGGKSP II SD DMD AV++A +FFN G+ C A R FV+ +I+D F++ E KK +G+P D + + GPQ +E + K+L G K+GAKLV GG R + GYF++PT+F V DDM IAREE FGP+ + +F +DEVI RAN +EYGLA+ VFT D+ KA + + AGTV++NTYN APFGG+K SG G++ G+ AL+ Y + K+V V+
Sbjct: 23 ANYSSLPQPQTTPDILYTGVFINNEWHKSKSGKIFETINPTTAEVIAEIQCADKEDIDIAVQAARNAFKLGSPWRRMDASERGRLLYRLADLMERDQVYLASLETLDNGKPYSMSYNVDLPTAIKNLRYFAGWADKNHGKTIPMDG----DFFTYTRHEPVGVCGQIIPWNFPILMMAWKLGPALATGNTIVLKPAEQTSLTALYIAQLVKEAGFPEGVVNVVPGFGT-AGAALANHCDVDKVAFTGSTDVGKLIQLASGNTNLKRVTLELGGKSPNIILSDTDMDYAVETAHFGLFFNMGQCCCAGSRTFVEDKIYDEFVERSAERAKKRTVGNPFDLNTEQGPQVNEEQMEKILGMIKTGKKQGAKLVAGGSRPEGLPGYFVQPTVFADVQDDMTIAREEIFGPVQQLIRFKKLDEVIERANNSEYGLAAAVFTKDLDKANYIVGGLRAGTVWVNTYNVLAAQAPFGGYKMSGHGRENGEYALSNYTEVKSVIVK 514
BLAST of 10-formyltetrahydrofolate dehydrogenase vs. Ensembl Fly
Match: CG31075 (gene:FBgn0051075 transcript:FBtr0307506) HSP 1 Score: 439.113 bits (1128), Expect = 2.787e-142 Identity = 235/478 (49.16%), Postives = 322/478 (67.36%), Query Frame = 3
Query: 1578 QIFINNEFVNSESGKEYDSKNPSDESVICRVSYSSXXXXXXXXXXXXXXFEF-GEWGKMSARDRGRILYKLADLMEEHAEELATLESLDSGAVYTLALKTHIGMSIETFRYFAGWCDKIQGSTIPISNARPNKNLSFTKKEPIGVCGIITPWNYPLMMLAWKVAACLAAGNTVVLKPAQVTPLASLKFCELSVEAGFPPGVINVLPGSGAIAGTAISEHPDIRKLGFTGSTAIGQTIMSSCAKSNLKKCSLELGGKSPLIIFSDCDMDKAVKSACSSVFFNKGENCIAAGRIFVDVRIHDVFLKLVVEDVKKMKIGDPLDRSVDHGPQNHEIHLLKLLEFCDIGVKEGAKLVFGGKRCDRKGYFMEPTIFTSVTDDMYIAREESFGPIMIISKFYDIDEVIVRANKTEYGLASGVFTNDISKALRVADAIDAGTVFINTYNKTDVAAPFGGFKQSGFGKDLGQEALNEYLKTKTVTVE 3008
Q+FINNEFV+S SGK + + NP+ I +VS K D+D+AVKAAK+AF EW K+S R ++ KL LM+ LA+LE+ D+G Y AL + SI T +Y+AGW DK G TIP +S T+KEP+GV G I PWNYPL+MLAWK LA G T+++KPA+ TPL +L L+ EAGFP GVINV+ G G AG AIS HPDI K+ FTGS IG+ +M + A SNLK+ SLELGGKSP+++F D D+D AV++ ++F N G++C A R +V +I+D F+ K K+G+P +++V GPQ + L K+L + + G KEGAKL GGKR G+F+EPT+F+ V DDM IA+EE FGP+ I KF ++E+I RAN +YGLA+GV TNDI+KAL+ A+ +DAG+V+IN Y+ + PFGG+K SG G++LG++ L+ YL+TKT+T++
Sbjct: 35 QLFINNEFVDSVSGKTFATFNPATSKEIVQVSEGDKADIDLAVKAAKKAFHRDSEWRKLSPLQRTNLMNKLCALMDRDKAFLASLETQDNGKPYAEAL-FDVTYSILTLQYYAGWTDKFFGDTIPAGGF-----VSMTRKEPVGVVGQIIPWNYPLLMLAWKWGPALAVGCTIIMKPAEQTPLTALHMAALAKEAGFPAGVINVVNGFGPTAGAAISAHPDIAKVAFTGSVEIGRIVMQAAATSNLKRVSLELGGKSPVVVFDDADIDFAVETTHEALFSNHGQSCCAGSRTYVHEKIYDEFVAKAAAKAKARKVGNPFEQNVQQGPQIDDDMLTKVLGYIESGKKEGAKLQAGGKRIGNVGFFVEPTVFSDVKDDMRIAQEEIFGPVQSIFKFSSLEEMIDRANNVQYGLAAGVITNDINKALKFANNVDAGSVWINCYDAVLPSTPFGGYKHSGIGRELGKDGLDNYLETKTITMK 506
BLAST of 10-formyltetrahydrofolate dehydrogenase vs. Ensembl Fly
Match: CG31075 (gene:FBgn0051075 transcript:FBtr0085080) HSP 1 Score: 437.187 bits (1123), Expect = 6.061e-142 Identity = 235/482 (48.76%), Postives = 323/482 (67.01%), Query Frame = 3
Query: 1566 PIPHQIFINNEFVNSESGKEYDSKNPSDESVICRVSYSSXXXXXXXXXXXXXXFEF-GEWGKMSARDRGRILYKLADLMEEHAEELATLESLDSGAVYTLALKTHIGMSIETFRYFAGWCDKIQGSTIPISNARPNKNLSFTKKEPIGVCGIITPWNYPLMMLAWKVAACLAAGNTVVLKPAQVTPLASLKFCELSVEAGFPPGVINVLPGSGAIAGTAISEHPDIRKLGFTGSTAIGQTIMSSCAKSNLKKCSLELGGKSPLIIFSDCDMDKAVKSACSSVFFNKGENCIAAGRIFVDVRIHDVFLKLVVEDVKKMKIGDPLDRSVDHGPQNHEIHLLKLLEFCDIGVKEGAKLVFGGKRCDRKGYFMEPTIFTSVTDDMYIAREESFGPIMIISKFYDIDEVIVRANKTEYGLASGVFTNDISKALRVADAIDAGTVFINTYNKTDVAAPFGGFKQSGFGKDLGQEALNEYLKTKTVTVE 3008
P ++FINNEFV+S SGK + + NP+ I +VS K D+D+AVKAAK+AF EW K+S R ++ KL LM+ LA+LE+ D+G Y AL + SI T +Y+AGW DK G TIP +S T+KEP+GV G I PWNYPL+MLAWK LA G T+++KPA+ TPL +L L+ EAGFP GVINV+ G G AG AIS HPDI K+ FTGS IG+ +M + A SNLK+ SLELGGKSP+++F D D+D AV++ ++F N G++C A R +V +I+D F+ K K+G+P +++V GPQ + L K+L + + G KEGAKL GGKR G+F+EPT+F+ V DDM IA+EE FGP+ I KF ++E+I RAN +YGLA+GV TNDI+KAL+ A+ +DAG+V+IN Y+ + PFGG+K SG G++LG++ L+ YL+TKT+T++
Sbjct: 8 PKYTKLFINNEFVDSVSGKTFATFNPATSKEIVQVSEGDKADIDLAVKAAKKAFHRDSEWRKLSPLQRTNLMNKLCALMDRDKAFLASLETQDNGKPYAEAL-FDVTYSILTLQYYAGWTDKFFGDTIPAGGF-----VSMTRKEPVGVVGQIIPWNYPLLMLAWKWGPALAVGCTIIMKPAEQTPLTALHMAALAKEAGFPAGVINVVNGFGPTAGAAISAHPDIAKVAFTGSVEIGRIVMQAAATSNLKRVSLELGGKSPVVVFDDADIDFAVETTHEALFSNHGQSCCAGSRTYVHEKIYDEFVAKAAAKAKARKVGNPFEQNVQQGPQIDDDMLTKVLGYIESGKKEGAKLQAGGKRIGNVGFFVEPTVFSDVKDDMRIAQEEIFGPVQSIFKFSSLEEMIDRANNVQYGLAAGVITNDINKALKFANNVDAGSVWINCYDAVLPSTPFGGYKHSGIGRELGKDGLDNYLETKTITMK 483
BLAST of 10-formyltetrahydrofolate dehydrogenase vs. Ensembl Zebrafish
Match: aldh1l2 (aldehyde dehydrogenase 1 family, member L2 [Source:ZFIN;Acc:ZDB-GENE-100426-6]) HSP 1 Score: 1119.76 bits (2895), Expect = 0.000e+0 Identity = 539/855 (63.04%), Postives = 678/855 (79.30%), Query Frame = 3
Query: 459 GTKVFKIPKWRVNNQIIKEVFEEYRSINAELNVLAFCTQFIPMEVINAPKHRSIIYHPSLLPKHRGASAINWTLINGDLKGGLTIFWADDGLDTGPVLLQRECDVHINDTVDSLYSRFMMPEGIKAMVEAVRQIESGRAPAIAQYHPDHSYDQMVKKSTAEINWNQSGLSLHNFIRGHDKVPGAWSWINGQKVTFYGSQLWYHDVVHDGPSLAIQGLSDPAVLHNHGLLIRGSDNQWINIAQLKFEDTGKTVQASKYGKGDEITTMADLSEDERAMEIPLMKIWKSILMG-SDIEPESDFFKLGGTSMDVTRIIEQIKCN-FNVELKIDHIYLYSTFDTLFKWIVLRKRGGGSQKKLHYDAVIINANKMTFPIPHQIFINNEFVNSESGKEYDSKNPSDESVICRVSYSSXXXXXXXXXXXXXXFEFGEWGKMSARDRGRILYKLADLMEEHAEELATLESLDSGAVYTLALKTHIGMSIETFRYFAGWCDKIQGSTIPISNARPNKNLSFTKKEPIGVCGIITPWNYPLMMLAWKVAACLAAGNTVVLKPAQVTPLASLKFCELSVEAGFPPGVINVLPGSGAIAGTAISEHPDIRKLGFTGSTAIGQTIMSSCAKSNLKKCSLELGGKSPLIIFSDCDMDKAVKSACSSVFFNKGENCIAAGRIFVDVRIHDVFLKLVVEDVKKMKIGDPLDRSVDHGPQNHEIHLLKLLEFCDIGVKEGAKLVFGGKRCDRKGYFMEPTIFTSVTDDMYIAREESFGPIMIISKFY--DIDEVIVRANKTEYGLASGVFTNDISKALRVADAIDAGTVFINTYNKTDVAAPFGGFKQSGFGKDLGQEALNEYLKTKTVTVEY 3011
GT VFK P+WRV + I EV E Y+++ AELNV+ FC+QFIPM VI+ PKH SIIYHPS+LPKHRGASAINWTLI GD K G ++FWADDGLDTGP+LLQ+EC V NDTVD+LY+RF+ PEGIKAMVEAV+ I +G+AP I Q SY+ + KKS A++N Q ++HN+IRGHDKVPGAW ++G+ VT YGS + V P + I+G S P ++ GLL+ GSD + + + L+FED GK + ASKY +E ++ DL++DE+ M + IWK IL + IE +DFFK G SMDV R++E++K V+L+ + +Y+ +TF + + +V R RG ++++ D N MT +P+Q FIN +F +++ GK Y++ NP+D SVIC+VSY+S DVD AV AAKEAF+ G WGKM+ RDRG++LY+LADLMEEH EELAT+E++DSGAVYTLALKTH+GMSI+TFRYFAGWCDKIQGSTIPI+ ARPN+NL+FTKKEP+GVC I+ PWNYPLMMLAWK AACLAAGNT+VLKPAQVTPL +LKF EL+++AG P GVIN++PGSG + G +SEHPDIRKLGFTGST IG+ IM SCA SNLKK SLELGGKSPLIIFSDCDMDKAV+ SSV+FNKGENCIAAGR+FV+ IHD +++ VVE++KKMKIGDPLDRS DHGPQNH+ H+ KL+E+C+IGVKEGA LV+GG++ DR G+FMEPT+FT V D M+IA+EESFGP+M++SKF D+D V+ RAN TE+GLASGVFT DI+KA+ V++ ++AGTVFINTYNKTDVAAPFGGFKQSGFGKDLG++AL+EYL+TK VTVEY
Sbjct: 64 GTPVFKFPRWRVKGKPIPEVVEAYKAVGAELNVMPFCSQFIPMNVIDFPKHGSIIYHPSILPKHRGASAINWTLIEGDKKAGFSVFWADDGLDTGPILLQKECQVEPNDTVDTLYNRFLFPEGIKAMVEAVQLIANGKAPKIPQSEEGASYEGIQKKSNAKVNMAQPAEAIHNWIRGHDKVPGAWVVMDGKPVTVYGSSVLSGSVPAGQP-IDIEGASQPGLITKSGLLLFGSDGKALQVKSLQFED-GKMIPASKYFSSEESASL-DLTDDEKKMAEEIRAIWKGILSNVAAIEETTDFFKCGAASMDVVRLVEEVKQKCAGVQLQNEDVYMATTFQSFIQMLVRRLRGEDQEEEMLIDYATKEVNNMTVKMPYQCFINGKFEDADDGKTYNTVNPTDGSVICKVSYASVADVDKAVSAAKEAFDNGPWGKMNPRDRGQLLYRLADLMEEHQEELATIETIDSGAVYTLALKTHVGMSIQTFRYFAGWCDKIQGSTIPINQARPNRNLTFTKKEPLGVCAIVIPWNYPLMMLAWKSAACLAAGNTLVLKPAQVTPLTALKFAELTIKAGIPKGVINIVPGSGGLVGQRMSEHPDIRKLGFTGSTPIGKQIMKSCAVSNLKKVSLELGGKSPLIIFSDCDMDKAVRMGMSSVYFNKGENCIAAGRLFVEESIHDEYIRRVVEEIKKMKIGDPLDRSTDHGPQNHKAHMDKLVEYCEIGVKEGATLVYGGRQVDRPGFFMEPTVFTDVEDHMFIAKEESFGPVMVVSKFKDGDVDGVLSRANDTEFGLASGVFTRDINKAMYVSERLEAGTVFINTYNKTDVAAPFGGFKQSGFGKDLGEDALHEYLRTKAVTVEY 915 HSP 2 Score: 68.9366 bits (167), Expect = 3.070e-11 Identity = 27/69 (39.13%), Postives = 48/69 (69.57%), Query Frame = 1
Query: 112 RMKIAIIGQSIFGAQVYKELKNEGHDIVGVFTIPDRNGRSDPLGIFYWE*GFTTLLMTSKKSQGRPLAQ 318
++K+A+IGQS+FG +VY L+ +GH +VGVFT+PD++G++DPL + + G + +G+P+ +
Sbjct: 14 KLKLALIGQSLFGQEVYTNLRKQGHKVVGVFTVPDKDGKADPLAVVAEKDGTPVFKFPRWRVKGKPIPE 82
BLAST of 10-formyltetrahydrofolate dehydrogenase vs. Ensembl Zebrafish
Match: aldh1l1 (aldehyde dehydrogenase 1 family, member L1 [Source:ZFIN;Acc:ZDB-GENE-100519-4]) HSP 1 Score: 1108.21 bits (2865), Expect = 0.000e+0 Identity = 547/863 (63.38%), Postives = 679/863 (78.68%), Query Frame = 3
Query: 438 AMEAIDLGTKVFKIPKWRVNNQIIKEVFEEYRSINAELNVLAFCTQFIPMEVINAPKHRSIIYHPSLLPKHRGASAINWTLINGDLKGGLTIFWADDGLDTGPVLLQRECDVHINDTVDSLYSRFMMPEGIKAMVEAVRQIESGRAPAIAQYHPDHSYDQMVKKSTAEINWNQSGLSLHNFIRGHDKVPGAWSWINGQKVTFYGSQLWYHD-VVHDGPSLAIQGLSDPAVLHNHGLLIRGSDNQWINIAQLKFEDTGKTVQASKYGKGDEITTMADLSEDERAMEIPLMKIWKSILMGSD-IEPESDFFKLGGTSMDVTRIIEQIKCNF-NVELKIDHIYLYSTFDTLFKWIVLRKRGGGSQKKLHYDAVIINANKMTFPIPHQIFINNEFVNSESGKEYDSKNPSDESVICRVSYSSXXXXXXXXXXXXXXFEFGEWGKMSARDRGRILYKLADLMEEHAEELATLESLDSGAVYTLALKTHIGMSIETFRYFAGWCDKIQGSTIPISNARPNKNLSFTKKEPIGVCGIITPWNYPLMMLAWKVAACLAAGNTVVLKPAQVTPLASLKFCELSVEAGFPPGVINVLPGSGAIAGTAISEHPDIRKLGFTGSTAIGQTIMSSCAKSNLKKCSLELGGKSPLIIFSDCDMDKAVKSACSSVFFNKGENCIAAGRIFVDVRIHDVFLKLVVEDVKKMKIGDPLDRSVDHGPQNHEIHLLKLLEFCDIGVKEGAKLVFGGKRCDRKGYFMEPTIFTSVTDDMYIAREESFGPIMIISKFY--DIDEVIVRANKTEYGLASGVFTNDISKALRVADAIDAGTVFINTYNKTDVAAPFGGFKQSGFGKDLGQEALNEYLKTKTVTVEY 3011
A+EA G VFK P+WR+ + I EV ++Y+++ AELNVL FC+QFIPMEVI+ PKH SIIYHPSLLP+HRGASAINWTLI+GD KGG T+FWADDGLDTGP+LLQRECDV ND V+S+Y RF+ PEG+K MVEAVR I +G+AP I Q +Y+ + KK ++I+WNQ ++HN+IRG+D+VPGAW+ I+G+ V+FYGS L +D +G L I G S A++ +GL++ G+D + + + L+FED GK + S+Y K +T+ +LSEDE + +WKSIL + IE +DFFK G SMDV R++E++K ++L+ + +Y+ ++F + V + RG +++ + D V N MT IPHQ+FIN EFV++E GK Y S NP+D VIC VS + DV+ AV AAKEAFE GEWGKM+ RDRG++LYKLADLM++H EELAT+ES+DSGAVYTLALKTHIGMSI+TFRYFAGWCDKIQG TIPI+ ARPN+NL+FTKKEPIGVCGI+ PWNYPLMMLAWK AACLAAGNTVVLKPAQVTPL +LKF EL+ A FP GV+N+LPGSG++ G +S+HPD+RKLGFTGST IG+ IM SCA SN+KK SLELGGKSPLIIF+DCD+DKAV+ SSVFFNKGENCIAAGR+F++ IHD+FL+ VV +++KMKIGDPLDRS DHGPQNH+ HL KL+E+C+ GVKEGAKLV GGK+ +R G+F EPT+FT V D MYIA EESFGP+MIISKF ++D+V+ RAN TE+GLASGVFT DISKAL V++ + AGTVFINTYNKTDVAAPFGGFKQSGFGKDLGQEALNEYLKTK VTVEY
Sbjct: 43 AIEAEKDGVPVFKFPRWRLKGKAITEVVDQYKAVGAELNVLPFCSQFIPMEVIDHPKHGSIIYHPSLLPRHRGASAINWTLIHGDKKGGFTVFWADDGLDTGPILLQRECDVEPNDNVNSIYKRFLFPEGVKGMVEAVRLIATGKAPRIKQPEEGATYECIQKKENSKIDWNQPAEAIHNWIRGNDRVPGAWAEIDGKSVSFYGSTLLENDHFSSNGQPLKIPGASRAALVTKNGLVLFGNDGKMLLVKNLQFED-GKMIPGSQYFKAG-VTSTVELSEDENRFAEQMRVVWKSILTNVEKIEDTTDFFKSGAASMDVVRLVEEVKLRAAQLQLQNEDVYMATSFQEFIQMCVRKLRGEDEEEEFNVDYVEKKLNNMTIHIPHQLFINGEFVDAEGGKTYKSINPTDGQVICDVSLAQISDVEKAVAAAKEAFEEGEWGKMNPRDRGKLLYKLADLMKQHQEELATIESIDSGAVYTLALKTHIGMSIQTFRYFAGWCDKIQGCTIPINQARPNRNLTFTKKEPIGVCGIVIPWNYPLMMLAWKTAACLAAGNTVVLKPAQVTPLTALKFAELTALAKFPKGVVNILPGSGSLVGQRLSDHPDVRKLGFTGSTEIGKHIMKSCAVSNVKKVSLELGGKSPLIIFNDCDLDKAVRMGMSSVFFNKGENCIAAGRLFIEESIHDIFLERVVSEIRKMKIGDPLDRSTDHGPQNHKAHLDKLVEYCEKGVKEGAKLVCGGKQVERPGFFFEPTVFTDVQDHMYIAVEESFGPVMIISKFSNGEVDKVLQRANATEFGLASGVFTRDISKALYVSEKLQAGTVFINTYNKTDVAAPFGGFKQSGFGKDLGQEALNEYLKTKCVTVEY 903 HSP 2 Score: 79.337 bits (194), Expect = 2.199e-14 Identity = 34/44 (77.27%), Postives = 40/44 (90.91%), Query Frame = 1
Query: 115 MKIAIIGQSIFGAQVYKELKNEGHDIVGVFTIPDRNGRSDPLGI 246
MKIA+IGQS+FG +VYKELKNEGH IVGVFTIPD++G+ DPL I
Sbjct: 1 MKIAVIGQSLFGQEVYKELKNEGHMIVGVFTIPDKDGKVDPLAI 44
BLAST of 10-formyltetrahydrofolate dehydrogenase vs. Ensembl Zebrafish
Match: aldh1l1 (aldehyde dehydrogenase 1 family, member L1 [Source:ZFIN;Acc:ZDB-GENE-100519-4]) HSP 1 Score: 1107.05 bits (2862), Expect = 0.000e+0 Identity = 546/863 (63.27%), Postives = 678/863 (78.56%), Query Frame = 3
Query: 438 AMEAIDLGTKVFKIPKWRVNNQIIKEVFEEYRSINAELNVLAFCTQFIPMEVINAPKHRSIIYHPSLLPKHRGASAINWTLINGDLKGGLTIFWADDGLDTGPVLLQRECDVHINDTVDSLYSRFMMPEGIKAMVEAVRQIESGRAPAIAQYHPDHSYDQMVKKSTAEINWNQSGLSLHNFIRGHDKVPGAWSWINGQKVTFYGSQLWYHD-VVHDGPSLAIQGLSDPAVLHNHGLLIRGSDNQWINIAQLKFEDTGKTVQASKYGKGDEITTMADLSEDERAMEIPLMKIWKSILMGSD-IEPESDFFKLGGTSMDVTRIIEQIKCNF-NVELKIDHIYLYSTFDTLFKWIVLRKRGGGSQKKLHYDAVIINANKMTFPIPHQIFINNEFVNSESGKEYDSKNPSDESVICRVSYSSXXXXXXXXXXXXXXFEFGEWGKMSARDRGRILYKLADLMEEHAEELATLESLDSGAVYTLALKTHIGMSIETFRYFAGWCDKIQGSTIPISNARPNKNLSFTKKEPIGVCGIITPWNYPLMMLAWKVAACLAAGNTVVLKPAQVTPLASLKFCELSVEAGFPPGVINVLPGSGAIAGTAISEHPDIRKLGFTGSTAIGQTIMSSCAKSNLKKCSLELGGKSPLIIFSDCDMDKAVKSACSSVFFNKGENCIAAGRIFVDVRIHDVFLKLVVEDVKKMKIGDPLDRSVDHGPQNHEIHLLKLLEFCDIGVKEGAKLVFGGKRCDRKGYFMEPTIFTSVTDDMYIAREESFGPIMIISKFY--DIDEVIVRANKTEYGLASGVFTNDISKALRVADAIDAGTVFINTYNKTDVAAPFGGFKQSGFGKDLGQEALNEYLKTKTVTVEY 3011
A+EA G VFK P+WR+ + I EV ++Y+++ AELNVL FC+QFIPMEVI+ PKH SIIYHPSLLP+HRGASAINWTLI+GD KGG T+FWADDGLDTGP+LLQRECDV ND V+S+Y RF+ PEG+K MVEAVR I +G+AP I Q +Y+ + KK ++I+WNQ ++HN+IRG+D+VPGAW+ I+G+ V+FYGS L +D +G L I G S A++ +GL++ G+D + + + L+FED GK + S+Y K +T+ +LSEDE + +WKSIL + IE +DFFK G SMDV R++E++K ++L+ + +Y+ ++F + V + RG +++ + D V N MT IPHQ+FIN EFV++E GK Y S NP+D IC VS + DV+ AV AAKEAFE GEWG+M+ RDRG++LYKLADLME+H EELAT+ES+DSGAVYTLALKTHIGMSI+TFRYFAGWCDKIQG TIPI+ ARPN+NL+FTKKEPIGVCGI+ PWNYPLMMLAWK AACLAAGNTVVLKPAQVTPL +LKF EL+ A FP GV+N+LPGSG++ G +S+HPD+RKLGFTGST IG+ IM SCA SN+KK SLELGGKSPLIIF+DCD+DKAV+ SSVFFNKGENCIAAGR+F++ IHD+FL+ VV +++KMKIGDPLDRS DHGPQNH+ HL KL+E+C+ GVKEGAKLV GGK+ +R G+F EPT+FT V D MYIA EESFGP+MIISKF ++D+V+ RAN TE+GLASGVFT DISKAL V++ + AGTVFINTYNKTDVAAPFGGFKQSGFGKDLGQEALNEYLKTK VTVEY
Sbjct: 43 AIEAEKDGVPVFKFPRWRLKGKAITEVVDQYKAVGAELNVLPFCSQFIPMEVIDHPKHGSIIYHPSLLPRHRGASAINWTLIHGDKKGGFTVFWADDGLDTGPILLQRECDVEPNDNVNSIYKRFLFPEGVKGMVEAVRLIATGKAPRIKQPEEGATYECIQKKENSKIDWNQPAEAIHNWIRGNDRVPGAWAEIDGKSVSFYGSTLLENDHFSSNGQPLEIPGASRAALVTKNGLVLFGNDGKMLLVKNLQFED-GKMIPGSQYFKAG-VTSTVELSEDENRFAEQMRVVWKSILTNVEKIEDTTDFFKSGAASMDVVRLVEEVKLRAAQLQLQNEDVYMATSFQEFIQMCVRKLRGEDEEEEFNVDYVEKKLNNMTIHIPHQLFINGEFVDAEGGKTYKSINPTDGQAICDVSLAQISDVEKAVAAAKEAFEEGEWGRMNPRDRGKLLYKLADLMEQHQEELATIESIDSGAVYTLALKTHIGMSIQTFRYFAGWCDKIQGCTIPINQARPNRNLTFTKKEPIGVCGIVIPWNYPLMMLAWKTAACLAAGNTVVLKPAQVTPLTALKFAELTALAKFPKGVVNILPGSGSLVGQRLSDHPDVRKLGFTGSTEIGKHIMKSCAVSNVKKVSLELGGKSPLIIFNDCDLDKAVRMGMSSVFFNKGENCIAAGRLFIEESIHDIFLERVVSEIRKMKIGDPLDRSTDHGPQNHKAHLDKLVEYCEKGVKEGAKLVCGGKQVERPGFFFEPTVFTDVQDHMYIAVEESFGPVMIISKFSNGEVDKVLQRANATEFGLASGVFTRDISKALYVSEKLQAGTVFINTYNKTDVAAPFGGFKQSGFGKDLGQEALNEYLKTKCVTVEY 903 HSP 2 Score: 79.337 bits (194), Expect = 2.199e-14 Identity = 34/44 (77.27%), Postives = 40/44 (90.91%), Query Frame = 1
Query: 115 MKIAIIGQSIFGAQVYKELKNEGHDIVGVFTIPDRNGRSDPLGI 246
MKIA+IGQS+FG +VYKELKNEGH IVGVFTIPD++G+ DPL I
Sbjct: 1 MKIAVIGQSLFGQEVYKELKNEGHMIVGVFTIPDKDGKVDPLAI 44
BLAST of 10-formyltetrahydrofolate dehydrogenase vs. Ensembl Zebrafish
Match: aldh1a2 (aldehyde dehydrogenase 1 family, member A2 [Source:ZFIN;Acc:ZDB-GENE-011010-3]) HSP 1 Score: 478.789 bits (1231), Expect = 3.713e-157 Identity = 255/499 (51.10%), Postives = 334/499 (66.93%), Query Frame = 3
Query: 1533 AVIINANKMTFPIPH------QIFINNEFVNSESGKEYDSKNPSDESVICRVSYSSXXXXXXXXXXXXXXFEFGE-WGKMSARDRGRILYKLADLMEEHAEELATLESLDSGAVYTLALKTHIGMSIETFRYFAGWCDKIQGSTIPISNARPNKNLSFTKKEPIGVCGIITPWNYPLMMLAWKVAACLAAGNTVVLKPAQVTPLASLKFCELSVEAGFPPGVINVLPGSGAIAGTAISEHPDIRKLGFTGSTAIGQTIMSSCAKSNLKKCSLELGGKSPLIIFSDCDMDKAVKSACSSVFFNKGENCIAAGRIFVDVRIHDVFLKLVVEDVKKMKIGDPLDRSVDHGPQNHEIHLLKLLEFCDIGVKEGAKLVFGGKRCDRKGYFMEPTIFTSVTDDMYIAREESFGPIMIISKFYDIDEVIVRANKTEYGLASGVFTNDISKALRVADAIDAGTVFINTYNKTDVAAPFGGFKQSGFGKDLGQEALNEYLKTKTVTVE 3008
A++ + + M P+P+ +IFINNE+ +S SGK + + NP+ IC V S K DVD AV+AA+ AF G W KM A +RG++L+KLADL+E + LATLESLDSG + + I+TFRY+AGW DKI GSTIPI + + T+ EPIGVCG I PWN+PL+M AWK+ L+ GNTVVLKPA+ TPL L L EAGFPPGV+N+LPG G AG AIS H I K+ FTGST +G+ I + KSNLK+ +LELGGKSP IIF+D D + A++ A VFFN G+ C A RIFV+ I+D F++ VE ++ K+G+P D + +HGPQ E ++LE G+ EGAKL GGK KG+F+EPT+F++V D M IA+EE FGP+ I KF I+EVI RAN TEYGLA+ VFT DISKA+ ++ A+ AGTV+IN YN PFGGFK SG G++LG+ L EY + KT+T++
Sbjct: 18 ALMASLHLMPSPVPNPEIKYTKIFINNEWHDSVSGKVFHTYNPATGEKICDVQESDKADVDKAVQAARSAFSLGSVWRKMDASERGKLLFKLADLVERDSAYLATLESLDSGKPFLPCFFVDLQGIIKTFRYYAGWADKIHGSTIPIDG----EFFTLTRHEPIGVCGQIIPWNFPLVMTAWKLGPALSCGNTVVLKPAEQTPLTCLYLGALIKEAGFPPGVVNILPGYGPTAGAAISSHMGIDKVAFTGSTEVGKLIQEAAGKSNLKRVTLELGGKSPNIIFADADFELALEQAHQGVFFNNGQCCTAGSRIFVEEPIYDEFVRRSVERAQRRKVGNPFDPTTEHGPQVSEEQQRRVLELIQSGITEGAKLECGGKAPPTKGFFVEPTVFSNVKDHMRIAKEEIFGPVQQIMKFKTIEEVIERANNTEYGLAAAVFTRDISKAMTISAAVQAGTVWINCYNALSCQCPFGGFKMSGNGRELGEIGLKEYTELKTITMK 512
BLAST of 10-formyltetrahydrofolate dehydrogenase vs. Ensembl Zebrafish
Match: aldh1a2 (aldehyde dehydrogenase 1 family, member A2 [Source:ZFIN;Acc:ZDB-GENE-011010-3]) HSP 1 Score: 478.789 bits (1231), Expect = 3.713e-157 Identity = 255/499 (51.10%), Postives = 334/499 (66.93%), Query Frame = 3
Query: 1533 AVIINANKMTFPIPH------QIFINNEFVNSESGKEYDSKNPSDESVICRVSYSSXXXXXXXXXXXXXXFEFGE-WGKMSARDRGRILYKLADLMEEHAEELATLESLDSGAVYTLALKTHIGMSIETFRYFAGWCDKIQGSTIPISNARPNKNLSFTKKEPIGVCGIITPWNYPLMMLAWKVAACLAAGNTVVLKPAQVTPLASLKFCELSVEAGFPPGVINVLPGSGAIAGTAISEHPDIRKLGFTGSTAIGQTIMSSCAKSNLKKCSLELGGKSPLIIFSDCDMDKAVKSACSSVFFNKGENCIAAGRIFVDVRIHDVFLKLVVEDVKKMKIGDPLDRSVDHGPQNHEIHLLKLLEFCDIGVKEGAKLVFGGKRCDRKGYFMEPTIFTSVTDDMYIAREESFGPIMIISKFYDIDEVIVRANKTEYGLASGVFTNDISKALRVADAIDAGTVFINTYNKTDVAAPFGGFKQSGFGKDLGQEALNEYLKTKTVTVE 3008
A++ + + M P+P+ +IFINNE+ +S SGK + + NP+ IC V S K DVD AV+AA+ AF G W KM A +RG++L+KLADL+E + LATLESLDSG + + I+TFRY+AGW DKI GSTIPI + + T+ EPIGVCG I PWN+PL+M AWK+ L+ GNTVVLKPA+ TPL L L EAGFPPGV+N+LPG G AG AIS H I K+ FTGST +G+ I + KSNLK+ +LELGGKSP IIF+D D + A++ A VFFN G+ C A RIFV+ I+D F++ VE ++ K+G+P D + +HGPQ E ++LE G+ EGAKL GGK KG+F+EPT+F++V D M IA+EE FGP+ I KF I+EVI RAN TEYGLA+ VFT DISKA+ ++ A+ AGTV+IN YN PFGGFK SG G++LG+ L EY + KT+T++
Sbjct: 18 ALMASLHLMPSPVPNPEIKYTKIFINNEWHDSVSGKVFHTYNPATGEKICDVQESDKADVDKAVQAARSAFSLGSVWRKMDASERGKLLFKLADLVERDSAYLATLESLDSGKPFLPCFFVDLQGIIKTFRYYAGWADKIHGSTIPIDG----EFFTLTRHEPIGVCGQIIPWNFPLVMTAWKLGPALSCGNTVVLKPAEQTPLTCLYLGALIKEAGFPPGVVNILPGYGPTAGAAISSHMGIDKVAFTGSTEVGKLIQEAAGKSNLKRVTLELGGKSPNIIFADADFELALEQAHQGVFFNNGQCCTAGSRIFVEEPIYDEFVRRSVERAQRRKVGNPFDPTTEHGPQVSEEQQRRVLELIQSGITEGAKLECGGKAPPTKGFFVEPTVFSNVKDHMRIAKEEIFGPVQQIMKFKTIEEVIERANNTEYGLAAAVFTRDISKAMTISAAVQAGTVWINCYNALSCQCPFGGFKMSGNGRELGEIGLKEYTELKTITMK 512
BLAST of 10-formyltetrahydrofolate dehydrogenase vs. Ensembl Xenopus
Match: glra1 (glycine receptor alpha 1 [Source:Xenbase;Acc:XB-GENE-6035798]) HSP 1 Score: 1130.16 bits (2922), Expect = 0.000e+0 Identity = 556/863 (64.43%), Postives = 687/863 (79.61%), Query Frame = 3
Query: 438 AMEAIDLGTKVFKIPKWRVNNQIIKEVFEEYRSINAELNVLAFCTQFIPMEVINAPKHRSIIYHPSLLPKHRGASAINWTLINGDLKGGLTIFWADDGLDTGPVLLQRECDVHINDTVDSLYSRFMMPEGIKAMVEAVRQIESGRAPAIAQYHPDHSYDQMVKKSTAEINWNQSGLSLHNFIRGHDKVPGAWSWINGQKVTFYGSQLWYHDVVHDGPSLAIQGLSDPAVLHNHGLLIRGSDNQWINIAQLKFEDTGKTVQASKYGKGDEITTMADLSEDERAMEIPLMKIWKSILMG-SDIEPESDFFKLGGTSMDVTRIIEQIK--CNFNVELKIDHIYLYSTFDTLFKWIVLRKRGGGSQKKLHYDAVIINANKMTFPIPHQIFINNEFVNSESGKEYDSKNPSDESVICRVSYSSXXXXXXXXXXXXXXFEFGEWGKMSARDRGRILYKLADLMEEHAEELATLESLDSGAVYTLALKTHIGMSIETFRYFAGWCDKIQGSTIPISNARPNKNLSFTKKEPIGVCGIITPWNYPLMMLAWKVAACLAAGNTVVLKPAQVTPLASLKFCELSVEAGFPPGVINVLPGSGAIAGTAISEHPDIRKLGFTGSTAIGQTIMSSCAKSNLKKCSLELGGKSPLIIFSDCDMDKAVKSACSSVFFNKGENCIAAGRIFVDVRIHDVFLKLVVEDVKKMKIGDPLDRSVDHGPQNHEIHLLKLLEFCDIGVKEGAKLVFGGKRCDRKGYFMEPTIFTSVTDDMYIAREESFGPIMIISKFY--DIDEVIVRANKTEYGLASGVFTNDISKALRVADAIDAGTVFINTYNKTDVAAPFGGFKQSGFGKDLGQEALNEYLKTKTVTVEY 3011
A+ A GT VFK P+WRV + I EV E Y+S+ A+LNVL +CTQFIPM+VI++PK+ SIIYHPS+LP+HRGASAINWTLINGD K G ++FWADDGLDTGP+LLQR CDV NDTVD+LY+RF+ PEGIKAM+EAV+ I G+AP I Q +Y+ + KK A+I W+ S ++HN+IRGHDKVPGAW+ IN Q VT YGS L V G ++++G S P ++ +GL++ G+D + + I L+FED GK + ASKY D+ T+ +L+E E+A+E + IWK IL S IE +DFFK G SMDV R++E++K C +EL+ + +Y+ +TF+ F +V+RK G +++L D +N N MT +P+Q FIN +F ++++GK YD+ NP+D SVIC+V+Y S DVD AV AAK+AFE GEWGKM+ARDRGRILY+LADLMEEH EELAT+E++DSGAVYTLALKTH+GMS++TFRYFAGWCDKIQGSTIPI+ ARPN+NL+FTKKEP+GVC I+ PWNYPLMMLAWK AACLAAGNT+VLKPAQVTPL +LKF EL+V+AG P GVIN+LPGSG + G +SEHPDIRKLGFTGST IG+ IM SCA SNLKK SLELGGKSPLIIF+DCD+DKAV+ +V+FNKGENCIAAGR+FV+ IHD F+ VVE++KKM+IGDPLDRS DHGPQNH HL KLLE+C+IGVKEGA LV+GG++ R G+FMEPT+FT V D MY+A EESFGPIM+ISKF DID V+ RAN TEYGLASGVFT DISKA+ V++ +DAGTVFINTYNKTDVAAPFGGFKQSGFGKDLG+EAL+EYL+TK VTVEY
Sbjct: 65 AVAAEKDGTPVFKFPRWRVKGKSIPEVVEAYKSVGADLNVLPYCTQFIPMDVIDSPKNGSIIYHPSILPRHRGASAINWTLINGDKKAGFSVFWADDGLDTGPILLQRACDVEPNDTVDTLYNRFLFPEGIKAMLEAVQLIADGKAPRIGQPEDGATYEGIQKKENAKICWDNSAQAIHNWIRGHDKVPGAWTLINEQMVTLYGSSL-LDGPVPTGQPVSVEGASKPGLVTKNGLVLFGNDGKMLTIRNLQFED-GKMIPASKYFSKDDSATL-ELTEQEKAVESEIRNIWKGILSNVSVIENTTDFFKSGAASMDVVRLVEELKQKCE-GLELQNEDVYMATTFEE-FIQMVVRKLRGEDKEELVIDYASLNVNNMTVKMPYQCFINGQFADADNGKTYDTINPTDGSVICKVAYCSVADVDKAVAAAKDAFENGEWGKMNARDRGRILYRLADLMEEHQEELATIEAIDSGAVYTLALKTHVGMSVQTFRYFAGWCDKIQGSTIPINQARPNRNLTFTKKEPLGVCAIVIPWNYPLMMLAWKSAACLAAGNTLVLKPAQVTPLTALKFAELAVKAGVPKGVINILPGSGGLVGQRLSEHPDIRKLGFTGSTPIGKQIMKSCAVSNLKKVSLELGGKSPLIIFNDCDLDKAVRMGMGAVYFNKGENCIAAGRLFVEESIHDEFVTRVVEEIKKMRIGDPLDRSTDHGPQNHRAHLEKLLEYCEIGVKEGATLVYGGRKVPRPGFFMEPTVFTDVEDHMYLAEEESFGPIMVISKFKDGDIDGVLRRANNTEYGLASGVFTKDISKAMYVSEKLDAGTVFINTYNKTDVAAPFGGFKQSGFGKDLGEEALHEYLRTKAVTVEY 922 HSP 2 Score: 70.0922 bits (170), Expect = 2.223e-11 Identity = 25/48 (52.08%), Postives = 40/48 (83.33%), Query Frame = 1
Query: 103 FNPRMKIAIIGQSIFGAQVYKELKNEGHDIVGVFTIPDRNGRSDPLGI 246
+ ++++A+IGQS+FG +VY L+ EGH IVGVFT+PD++G++DPL +
Sbjct: 19 YQNKLRLALIGQSLFGQEVYNNLRKEGHKIVGVFTVPDKDGKADPLAV 66
BLAST of 10-formyltetrahydrofolate dehydrogenase vs. Ensembl Xenopus
Match: skida1 (SKI/DACH domain containing 1 [Source:Xenbase;Acc:XB-GENE-976606]) HSP 1 Score: 1129.39 bits (2920), Expect = 0.000e+0 Identity = 546/855 (63.86%), Postives = 675/855 (78.95%), Query Frame = 3
Query: 459 GTKVFKIPKWRVNNQIIKEVFEEYRSINAELNVLAFCTQFIPMEVINAPKHRSIIYHPSLLPKHRGASAINWTLINGDLKGGLTIFWADDGLDTGPVLLQRECDVHINDTVDSLYSRFMMPEGIKAMVEAVRQIESGRAPAIAQYHPDHSYDQMVKKSTAEINWNQSGLSLHNFIRGHDKVPGAWSWINGQKVTFYGSQLWYHDVVHDGPSLAIQGLSDPAVLHNHGLLIRGSDNQWINIAQLKFEDTGKTVQASKYGKGDEITTMADLSEDERAMEIPLMKIWKSILMG-SDIEPESDFFKLGGTSMDVTRIIEQIKCNFN-VELKIDHIYLYSTFDTLFKWIVLRKRGGGSQKKLHYDAVIINANKMTFPIPHQIFINNEFVNSESGKEYDSKNPSDESVICRVSYSSXXXXXXXXXXXXXXFEFGEWGKMSARDRGRILYKLADLMEEHAEELATLESLDSGAVYTLALKTHIGMSIETFRYFAGWCDKIQGSTIPISNARPNKNLSFTKKEPIGVCGIITPWNYPLMMLAWKVAACLAAGNTVVLKPAQVTPLASLKFCELSVEAGFPPGVINVLPGSGAIAGTAISEHPDIRKLGFTGSTAIGQTIMSSCAKSNLKKCSLELGGKSPLIIFSDCDMDKAVKSACSSVFFNKGENCIAAGRIFVDVRIHDVFLKLVVEDVKKMKIGDPLDRSVDHGPQNHEIHLLKLLEFCDIGVKEGAKLVFGGKRCDRKGYFMEPTIFTSVTDDMYIAREESFGPIMIISKFY--DIDEVIVRANKTEYGLASGVFTNDISKALRVADAIDAGTVFINTYNKTDVAAPFGGFKQSGFGKDLGQEALNEYLKTKTVTVEY 3011
G VFK P+WRV Q I EV E+Y+++ AELNVL FC+QFIPMEVI+ PKH SIIYHPS+LP+HRGASAINWTL+ GD GG TIFWADDGLDTG +LLQREC+V +DTV+++Y+RF+ PEG+K MVEAVR I G AP I Q +YD M KK A+INW+Q ++HNFIRG+DKVPGAW+ + Q++TF+GS + DG L I G PAV+ GL++ G+D Q +++ ++FED GK + AS+Y K + + LS++E+ + WK IL S+IE +DFFK G SMDV R++E++K N ++L+ + +Y+ + F+ + +V R RG +++L D V N MT IPHQ+FIN +F+++E GK YD+ NP+D + IC+VS + D+D AV AAKEAFE GEWGKM+ RDRGRILY+LAD+MEEH EELAT+ES+DSGAVYTLALKTH+GMSI+TFRYFAGWCDKIQGSTIPI+ ARPN+NL+FT++EPIGVCGI+ PWNYPLMMLAWK AACLAAGNTVVLKPAQVTPL +LKF ELSV+AG P GVIN+LPG+G++ G +S+HPD+RK+GFTGST IG+ IM SCA N+KK SLELGGKSPLIIF DCD+DKAV+ SSVFFNKGENCIAAGR+F++ IHD F+K VV +VKKMKIGDPLDRS DHGPQNH+ HL KL+E+C GVKEGAKLV+GGK+ +R G+F EPTIFT VTD+M+IA+EESFGPIMIISKF D+DEV+ RAN TE+GLASGVFT DISKAL V++ + AGTVF+NTYNKTDVAAPFGGFKQSGFGKDLG+EALNEYLKTK VT+EY
Sbjct: 50 GIPVFKFPRWRVKGQAIPEVVEKYKALEAELNVLPFCSQFIPMEVIDCPKHGSIIYHPSILPRHRGASAINWTLMQGDKIGGFTIFWADDGLDTGDILLQRECEVLPDDTVNTIYNRFLFPEGVKGMVEAVRLIAEGNAPRIKQATEGATYDPMQKKENAKINWDQPAEAIHNFIRGNDKVPGAWTVVGDQQLTFFGSSFISNGPAPDGQPLEIPGAFRPAVVTKTGLVLFGNDGQKLSVKNIQFED-GKMIPASQYYKTADSAAL-QLSDEEKKFSEEIRAAWKRILTNVSEIEDSTDFFKAGAASMDVVRLVEEVKLKCNGLQLQNEDVYMATKFEEFIQMVVRRLRGEDGEEELVVDYVEKEINNMTVKIPHQLFINGQFIDAEGGKTYDTVNPTDGTAICKVSLAQVSDIDRAVAAAKEAFENGEWGKMNPRDRGRILYRLADIMEEHQEELATIESIDSGAVYTLALKTHVGMSIQTFRYFAGWCDKIQGSTIPINQARPNRNLTFTRREPIGVCGIVIPWNYPLMMLAWKTAACLAAGNTVVLKPAQVTPLTALKFAELSVKAGIPKGVINILPGAGSLIGQRLSDHPDVRKIGFTGSTPIGKHIMKSCAVGNVKKVSLELGGKSPLIIFQDCDLDKAVRMGMSSVFFNKGENCIAAGRLFLEESIHDEFVKRVVGEVKKMKIGDPLDRSTDHGPQNHKAHLDKLIEYCQTGVKEGAKLVYGGKQVERPGFFFEPTIFTDVTDEMFIAKEESFGPIMIISKFKDGDVDEVLKRANNTEFGLASGVFTKDISKALYVSEKLQAGTVFVNTYNKTDVAAPFGGFKQSGFGKDLGEEALNEYLKTKAVTIEY 902 HSP 2 Score: 76.6406 bits (187), Expect = 1.826e-13 Identity = 31/43 (72.09%), Postives = 39/43 (90.70%), Query Frame = 1
Query: 115 MKIAIIGQSIFGAQVYKELKNEGHDIVGVFTIPDRNGRSDPLG 243
MKIA+IGQS+FG +VY+EL EGH +VGVFTIPD+NG++DPLG
Sbjct: 1 MKIAVIGQSLFGREVYRELLKEGHQVVGVFTIPDKNGKADPLG 43
BLAST of 10-formyltetrahydrofolate dehydrogenase vs. Ensembl Xenopus
Match: glra1 (glycine receptor alpha 1 [Source:Xenbase;Acc:XB-GENE-6035798]) HSP 1 Score: 1102.81 bits (2851), Expect = 0.000e+0 Identity = 543/847 (64.11%), Postives = 672/847 (79.34%), Query Frame = 3
Query: 438 AMEAIDLGTKVFKIPKWRVNNQIIKEVFEEYRSINAELNVLAFCTQFIPMEVINAPKHRSIIYHPSLLPKHRGASAINWTLINGDLKGGLTIFWADDGLDTGPVLLQRECDVHINDTVDSLYSRFMMPEGIKAMVEAVRQIESGRAPAIAQYHPDHSYDQMVKKSTAEINWNQSGLSLHNFIRGHDKVPGAWSWINGQKVTFYGSQLWYHDVVHDGPSLAIQGLSDPAVLHNHGLLIRGSDNQWINIAQLKFEDTGKTVQASKYGKGDEITTMADLSEDERAMEIPLMKIWKSILMG-SDIEPESDFFKLGGTSMDVTRIIEQIK--CNFNVELKIDHIYLYSTFDTLFKWIVLRKRGGGSQKKLHYDAVIINANKMTFPIPHQIFINNEFVNSESGKEYDSKNPSDESVICRVSYSSXXXXXXXXXXXXXXFEFGEWGKMSARDRGRILYKLADLMEEHAEELATLESLDSGAVYTLALKTHIGMSIETFRYFAGWCDKIQGSTIPISNARPNKNLSFTKKEPIGVCGIITPWNYPLMMLAWKVAACLAAGNTVVLKPAQVTPLASLKFCELSVEAGFPPGVINVLPGSGAIAGTAISEHPDIRKLGFTGSTAIGQTIMSSCAKSNLKKCSLELGGKSPLIIFSDCDMDKAVKSACSSVFFNKGENCIAAGRIFVDVRIHDVFLKLVVEDVKKMKIGDPLDRSVDHGPQNHEIHLLKLLEFCDIGVKEGAKLVFGGKRCDRKGYFMEPTIFTSVTDDMYIAREESFGPIMIISKFY--DIDEVIVRANKTEYGLASGVFTNDISKALRVADAIDAGTVFINTYNKTDVAAPFGGFKQSGFGKDLGQ 2963
A+ A GT VFK P+WRV + I EV E Y+S+ A+LNVL +CTQFIPM+VI++PK+ SIIYHPS+LP+HRGASAINWTLINGD K G ++FWADDGLDTGP+LLQR CDV NDTVD+LY+RF+ PEGIKAM+EAV+ I G+AP I Q +Y+ + KK A+I W+ S ++HN+IRGHDKVPGAW+ IN Q VT YGS L V G ++++G S P ++ +GL++ G+D + + I L+FED GK + ASKY D+ T+ +L+E E+A+E + IWK IL S IE +DFFK G SMDV R++E++K C +EL+ + +Y+ +TF+ F +V+RK G +++L D +N N MT +P+Q FIN +F ++++GK YD+ NP+D SVIC+V+Y S DVD AV AAK+AFE GEWGKM+ARDRGRILY+LADLMEEH EELAT+E++DSGAVYTLALKTH+GMS++TFRYFAGWCDKIQGSTIPI+ ARPN+NL+FTKKEP+GVC I+ PWNYPLMMLAWK AACLAAGNT+VLKPAQVTPL +LKF EL+V+AG P GVIN+LPGSG + G +SEHPDIRKLGFTGST IG+ IM SCA SNLKK SLELGGKSPLIIF+DCD+DKAV+ +V+FNKGENCIAAGR+FV+ IHD F+ VVE++KKM+IGDPLDRS DHGPQNH HL KLLE+C+IGVKEGA LV+GG++ R G+FMEPT+FT V D MY+A EESFGPIM+ISKF DID V+ RAN TEYGLASGVFT DISKA+ V++ +DAGTVFINTYNKTDVAAPFGGFKQSGFGKDLG+
Sbjct: 66 AVAAEKDGTPVFKFPRWRVKGKSIPEVVEAYKSVGADLNVLPYCTQFIPMDVIDSPKNGSIIYHPSILPRHRGASAINWTLINGDKKAGFSVFWADDGLDTGPILLQRACDVEPNDTVDTLYNRFLFPEGIKAMLEAVQLIADGKAPRIGQPEDGATYEGIQKKENAKICWDNSAQAIHNWIRGHDKVPGAWTLINEQMVTLYGSSL-LDGPVPTGQPVSVEGASKPGLVTKNGLVLFGNDGKMLTIRNLQFED-GKMIPASKYFSKDDSATL-ELTEQEKAVESEIRNIWKGILSNVSVIENTTDFFKSGAASMDVVRLVEELKQKCE-GLELQNEDVYMATTFEE-FIQMVVRKLRGEDKEELVIDYASLNVNNMTVKMPYQCFINGQFADADNGKTYDTINPTDGSVICKVAYCSVADVDKAVAAAKDAFENGEWGKMNARDRGRILYRLADLMEEHQEELATIEAIDSGAVYTLALKTHVGMSVQTFRYFAGWCDKIQGSTIPINQARPNRNLTFTKKEPLGVCAIVIPWNYPLMMLAWKSAACLAAGNTLVLKPAQVTPLTALKFAELAVKAGVPKGVINILPGSGGLVGQRLSEHPDIRKLGFTGSTPIGKQIMKSCAVSNLKKVSLELGGKSPLIIFNDCDLDKAVRMGMGAVYFNKGENCIAAGRLFVEESIHDEFVTRVVEEIKKMRIGDPLDRSTDHGPQNHRAHLEKLLEYCEIGVKEGATLVYGGRKVPRPGFFMEPTVFTDVEDHMYLAEEESFGPIMVISKFKDGDIDGVLRRANNTEYGLASGVFTKDISKAMYVSEKLDAGTVFINTYNKTDVAAPFGGFKQSGFGKDLGK 907 HSP 2 Score: 70.0922 bits (170), Expect = 2.223e-11 Identity = 25/48 (52.08%), Postives = 40/48 (83.33%), Query Frame = 1
Query: 103 FNPRMKIAIIGQSIFGAQVYKELKNEGHDIVGVFTIPDRNGRSDPLGI 246
+ ++++A+IGQS+FG +VY L+ EGH IVGVFT+PD++G++DPL +
Sbjct: 20 YQNKLRLALIGQSLFGQEVYNNLRKEGHKIVGVFTVPDKDGKADPLAV 67
BLAST of 10-formyltetrahydrofolate dehydrogenase vs. Ensembl Xenopus
Match: glra1 (glycine receptor alpha 1 [Source:Xenbase;Acc:XB-GENE-6035798]) HSP 1 Score: 1101.27 bits (2847), Expect = 0.000e+0 Identity = 543/847 (64.11%), Postives = 672/847 (79.34%), Query Frame = 3
Query: 438 AMEAIDLGTKVFKIPKWRVNNQIIKEVFEEYRSINAELNVLAFCTQFIPMEVINAPKHRSIIYHPSLLPKHRGASAINWTLINGDLKGGLTIFWADDGLDTGPVLLQRECDVHINDTVDSLYSRFMMPEGIKAMVEAVRQIESGRAPAIAQYHPDHSYDQMVKKSTAEINWNQSGLSLHNFIRGHDKVPGAWSWINGQKVTFYGSQLWYHDVVHDGPSLAIQGLSDPAVLHNHGLLIRGSDNQWINIAQLKFEDTGKTVQASKYGKGDEITTMADLSEDERAMEIPLMKIWKSILMG-SDIEPESDFFKLGGTSMDVTRIIEQIK--CNFNVELKIDHIYLYSTFDTLFKWIVLRKRGGGSQKKLHYDAVIINANKMTFPIPHQIFINNEFVNSESGKEYDSKNPSDESVICRVSYSSXXXXXXXXXXXXXXFEFGEWGKMSARDRGRILYKLADLMEEHAEELATLESLDSGAVYTLALKTHIGMSIETFRYFAGWCDKIQGSTIPISNARPNKNLSFTKKEPIGVCGIITPWNYPLMMLAWKVAACLAAGNTVVLKPAQVTPLASLKFCELSVEAGFPPGVINVLPGSGAIAGTAISEHPDIRKLGFTGSTAIGQTIMSSCAKSNLKKCSLELGGKSPLIIFSDCDMDKAVKSACSSVFFNKGENCIAAGRIFVDVRIHDVFLKLVVEDVKKMKIGDPLDRSVDHGPQNHEIHLLKLLEFCDIGVKEGAKLVFGGKRCDRKGYFMEPTIFTSVTDDMYIAREESFGPIMIISKFY--DIDEVIVRANKTEYGLASGVFTNDISKALRVADAIDAGTVFINTYNKTDVAAPFGGFKQSGFGKDLGQ 2963
A+ A GT VFK P+WRV + I EV E Y+S+ A+LNVL +CTQFIPM+VI++PK+ SIIYHPS+LP+HRGASAINWTLINGD K G ++FWADDGLDTGP+LLQR CDV NDTVD+LY+RF+ PEGIKAM+EAV+ I G+AP I Q +Y+ + KK A+I W+ S ++HN+IRGHDKVPGAW+ IN Q VT YGS L V G ++++G S P ++ +GL++ G+D + + I L+FED GK + ASKY D+ T+ +L+E E+A+E + IWK IL S IE +DFFK G SMDV R++E++K C +EL+ + +Y+ +TF+ F +V+RK G +++L D +N N MT +P+Q FIN +F ++++GK YD+ NP+D SVIC+V+Y S DVD AV AAK+AFE GEWGKM+ARDRGRILY+LADLMEEH EELAT+E++DSGAVYTLALKTH+GMS++TFRYFAGWCDKIQGSTIPI+ ARPN+NL+FTKKEP+GVC I+ PWNYPLMMLAWK AACLAAGNT+VLKPAQVTPL +LKF EL+V+AG P GVIN+LPGSG + G +SEHPDIRKLGFTGST IG+ IM SCA SNLKK SLELGGKSPLIIF+DCD+DKAV+ +V+FNKGENCIAAGR+FV+ IHD F+ VVE++KKM+IGDPLDRS DHGPQNH HL KLLE+C+IGVKEGA LV+GG++ R G+FMEPT+FT V D MY+A EESFGPIM+ISKF DID V+ RAN TEYGLASGVFT DISKA+ V++ +DAGTVFINTYNKTDVAAPFGGFKQSGFGKDLG+
Sbjct: 56 AVAAEKDGTPVFKFPRWRVKGKSIPEVVEAYKSVGADLNVLPYCTQFIPMDVIDSPKNGSIIYHPSILPRHRGASAINWTLINGDKKAGFSVFWADDGLDTGPILLQRACDVEPNDTVDTLYNRFLFPEGIKAMLEAVQLIADGKAPRIGQPEDGATYEGIQKKENAKICWDNSAQAIHNWIRGHDKVPGAWTLINEQMVTLYGSSL-LDGPVPTGQPVSVEGASKPGLVTKNGLVLFGNDGKMLTIRNLQFED-GKMIPASKYFSKDDSATL-ELTEQEKAVESEIRNIWKGILSNVSVIENTTDFFKSGAASMDVVRLVEELKQKCE-GLELQNEDVYMATTFEE-FIQMVVRKLRGEDKEELVIDYASLNVNNMTVKMPYQCFINGQFADADNGKTYDTINPTDGSVICKVAYCSVADVDKAVAAAKDAFENGEWGKMNARDRGRILYRLADLMEEHQEELATIEAIDSGAVYTLALKTHVGMSVQTFRYFAGWCDKIQGSTIPINQARPNRNLTFTKKEPLGVCAIVIPWNYPLMMLAWKSAACLAAGNTLVLKPAQVTPLTALKFAELAVKAGVPKGVINILPGSGGLVGQRLSEHPDIRKLGFTGSTPIGKQIMKSCAVSNLKKVSLELGGKSPLIIFNDCDLDKAVRMGMGAVYFNKGENCIAAGRLFVEESIHDEFVTRVVEEIKKMRIGDPLDRSTDHGPQNHRAHLEKLLEYCEIGVKEGATLVYGGRKVPRPGFFMEPTVFTDVEDHMYLAEEESFGPIMVISKFKDGDIDGVLRRANNTEYGLASGVFTKDISKAMYVSEKLDAGTVFINTYNKTDVAAPFGGFKQSGFGKDLGK 897 HSP 2 Score: 72.0182 bits (175), Expect = 4.431e-12 Identity = 27/56 (48.21%), Postives = 45/56 (80.36%), Query Frame = 1
Query: 79 FQHLHFHNFNPRMKIAIIGQSIFGAQVYKELKNEGHDIVGVFTIPDRNGRSDPLGI 246
F ++++ N ++++A+IGQS+FG +VY L+ EGH IVGVFT+PD++G++DPL +
Sbjct: 5 FAYIYYQN---KLRLALIGQSLFGQEVYNNLRKEGHKIVGVFTVPDKDGKADPLAV 57
BLAST of 10-formyltetrahydrofolate dehydrogenase vs. Ensembl Xenopus
Match: skida1 (SKI/DACH domain containing 1 [Source:Xenbase;Acc:XB-GENE-976606]) HSP 1 Score: 1098.58 bits (2840), Expect = 0.000e+0 Identity = 533/843 (63.23%), Postives = 661/843 (78.41%), Query Frame = 3
Query: 459 GTKVFKIPKWRVNNQIIKEVFEEYRSINAELNVLAFCTQFIPMEVINAPKHRSIIYHPSLLPKHRGASAINWTLINGDLKGGLTIFWADDGLDTGPVLLQRECDVHINDTVDSLYSRFMMPEGIKAMVEAVRQIESGRAPAIAQYHPDHSYDQMVKKSTAEINWNQSGLSLHNFIRGHDKVPGAWSWINGQKVTFYGSQLWYHDVVHDGPSLAIQGLSDPAVLHNHGLLIRGSDNQWINIAQLKFEDTGKTVQASKYGKGDEITTMADLSEDERAMEIPLMKIWKSILMG-SDIEPESDFFKLGGTSMDVTRIIEQIKCNFN-VELKIDHIYLYSTFDTLFKWIVLRKRGGGSQKKLHYDAVIINANKMTFPIPHQIFINNEFVNSESGKEYDSKNPSDESVICRVSYSSXXXXXXXXXXXXXXFEFGEWGKMSARDRGRILYKLADLMEEHAEELATLESLDSGAVYTLALKTHIGMSIETFRYFAGWCDKIQGSTIPISNARPNKNLSFTKKEPIGVCGIITPWNYPLMMLAWKVAACLAAGNTVVLKPAQVTPLASLKFCELSVEAGFPPGVINVLPGSGAIAGTAISEHPDIRKLGFTGSTAIGQTIMSSCAKSNLKKCSLELGGKSPLIIFSDCDMDKAVKSACSSVFFNKGENCIAAGRIFVDVRIHDVFLKLVVEDVKKMKIGDPLDRSVDHGPQNHEIHLLKLLEFCDIGVKEGAKLVFGGKRCDRKGYFMEPTIFTSVTDDMYIAREESFGPIMIISKFY--DIDEVIVRANKTEYGLASGVFTNDISKALRVADAIDAGTVFINTYNKTDVAAPFGGFKQSGFGKDLGQEALN 2975
G VFK P+WRV Q I EV E+Y+++ AELNVL FC+QFIPMEVI+ PKH SIIYHPS+LP+HRGASAINWTL+ GD GG TIFWADDGLDTG +LLQREC+V +DTV+++Y+RF+ PEG+K MVEAVR I G AP I Q +YD M KK A+INW+Q ++HNFIRG+DKVPGAW+ + Q++TF+GS + DG L I G PAV+ GL++ G+D Q +++ ++FED GK + AS+Y K + + LS++E+ + WK IL S+IE +DFFK G SMDV R++E++K N ++L+ + +Y+ + F+ + +V R RG +++L D V N MT IPHQ+FIN +F+++E GK YD+ NP+D + IC+VS + D+D AV AAKEAFE GEWGKM+ RDRGRILY+LAD+MEEH EELAT+ES+DSGAVYTLALKTH+GMSI+TFRYFAGWCDKIQGSTIPI+ ARPN+NL+FT++EPIGVCGI+ PWNYPLMMLAWK AACLAAGNTVVLKPAQVTPL +LKF ELSV+AG P GVIN+LPG+G++ G +S+HPD+RK+GFTGST IG+ IM SCA N+KK SLELGGKSPLIIF DCD+DKAV+ SSVFFNKGENCIAAGR+F++ IHD F+K VV +VKKMKIGDPLDRS DHGPQNH+ HL KL+E+C GVKEGAKLV+GGK+ +R G+F EPTIFT VTD+M+IA+EESFGPIMIISKF D+DEV+ RAN TE+GLASGVFT DISKAL V++ + AGTVF+NTYNKTDVAAPFGGFKQSGFGKDLG+ N
Sbjct: 72 GIPVFKFPRWRVKGQAIPEVVEKYKALEAELNVLPFCSQFIPMEVIDCPKHGSIIYHPSILPRHRGASAINWTLMQGDKIGGFTIFWADDGLDTGDILLQRECEVLPDDTVNTIYNRFLFPEGVKGMVEAVRLIAEGNAPRIKQATEGATYDPMQKKENAKINWDQPAEAIHNFIRGNDKVPGAWTVVGDQQLTFFGSSFISNGPAPDGQPLEIPGAFRPAVVTKTGLVLFGNDGQKLSVKNIQFED-GKMIPASQYYKTADSAAL-QLSDEEKKFSEEIRAAWKRILTNVSEIEDSTDFFKAGAASMDVVRLVEEVKLKCNGLQLQNEDVYMATKFEEFIQMVVRRLRGEDGEEELVVDYVEKEINNMTVKIPHQLFINGQFIDAEGGKTYDTVNPTDGTAICKVSLAQVSDIDRAVAAAKEAFENGEWGKMNPRDRGRILYRLADIMEEHQEELATIESIDSGAVYTLALKTHVGMSIQTFRYFAGWCDKIQGSTIPINQARPNRNLTFTRREPIGVCGIVIPWNYPLMMLAWKTAACLAAGNTVVLKPAQVTPLTALKFAELSVKAGIPKGVINILPGAGSLIGQRLSDHPDVRKIGFTGSTPIGKHIMKSCAVGNVKKVSLELGGKSPLIIFQDCDLDKAVRMGMSSVFFNKGENCIAAGRLFLEESIHDEFVKRVVGEVKKMKIGDPLDRSTDHGPQNHKAHLDKLIEYCQTGVKEGAKLVYGGKQVERPGFFFEPTIFTDVTDEMFIAKEESFGPIMIISKFKDGDVDEVLKRANNTEFGLASGVFTKDISKALYVSEKLQAGTVFVNTYNKTDVAAPFGGFKQSGFGKDLGKRFCN 912 HSP 2 Score: 68.9366 bits (167), Expect = 5.054e-11 Identity = 27/39 (69.23%), Postives = 35/39 (89.74%), Query Frame = 1
Query: 127 IIGQSIFGAQVYKELKNEGHDIVGVFTIPDRNGRSDPLG 243
+IGQS+FG +VY+EL EGH +VGVFTIPD+NG++DPLG
Sbjct: 27 LIGQSLFGREVYRELLKEGHQVVGVFTIPDKNGKADPLG 65
BLAST of 10-formyltetrahydrofolate dehydrogenase vs. Ensembl Mouse
Match: Aldh1l2 (aldehyde dehydrogenase 1 family, member L2 [Source:MGI Symbol;Acc:MGI:2444680]) HSP 1 Score: 1120.92 bits (2898), Expect = 0.000e+0 Identity = 549/863 (63.62%), Postives = 677/863 (78.45%), Query Frame = 3
Query: 438 AMEAIDLGTKVFKIPKWRVNNQIIKEVFEEYRSINAELNVLAFCTQFIPMEVINAPKHRSIIYHPSLLPKHRGASAINWTLINGDLKGGLTIFWADDGLDTGPVLLQRECDVHINDTVDSLYSRFMMPEGIKAMVEAVRQIESGRAPAIAQYHPDHSYDQMVKKSTAEINWNQSGLSLHNFIRGHDKVPGAWSWINGQKVTFYGSQLWYHDVVHDGPSLAIQGLSDPAVLHNHGLLIRGSDNQWINIAQLKFEDTGKTVQASKYGKGDEITTMADLSEDERAMEIPLMKIWKSILMGSD-IEPESDFFKLGGTSMDVTRIIEQIK--CNFNVELKIDHIYLYSTFDTLFKWIVLRKRGGGSQKKLHYDAVIINANKMTFPIPHQIFINNEFVNSESGKEYDSKNPSDESVICRVSYSSXXXXXXXXXXXXXXFEFGEWGKMSARDRGRILYKLADLMEEHAEELATLESLDSGAVYTLALKTHIGMSIETFRYFAGWCDKIQGSTIPISNARPNKNLSFTKKEPIGVCGIITPWNYPLMMLAWKVAACLAAGNTVVLKPAQVTPLASLKFCELSVEAGFPPGVINVLPGSGAIAGTAISEHPDIRKLGFTGSTAIGQTIMSSCAKSNLKKCSLELGGKSPLIIFSDCDMDKAVKSACSSVFFNKGENCIAAGRIFVDVRIHDVFLKLVVEDVKKMKIGDPLDRSVDHGPQNHEIHLLKLLEFCDIGVKEGAKLVFGGKRCDRKGYFMEPTIFTSVTDDMYIAREESFGPIMIISKFY--DIDEVIVRANKTEYGLASGVFTNDISKALRVADAIDAGTVFINTYNKTDVAAPFGGFKQSGFGKDLGQEALNEYLKTKTVTVEY 3011
A+ A GT VFK P+WR+ + IKEV E Y+S+ AELNVL FCTQFIPM+VI++PKH SIIYHPSLLP+HRGASAINWTLI GD K G ++FWADDGLDTGP+LLQR CDV NDTVDSLY+RF+ PEGIKAMVEAV+ I G+AP Q +Y+ + KK AE++W+Q LHN+IRGHDKVPGAW+ INGQ VTFYGS L V G L I+G P ++ +GL++ G+D + + + L+FED GK + AS+Y E T++ +L+ +E + + IW IL + IE +DFFK G +SMDV R++E+I+ C ++L+ + +Y+ + F + +V R RG + ++ D V N MT IP+Q FIN +FV++E G+ Y + NP+D + ICRVSY+S DVD AV AAK+AFE GEWG+M+ARDRGR++Y+LADLMEE+ EELAT+E+LDSGAVYTLALKTHIGMS++TFRYFAGWCDKIQGSTIPI+ ARPN NL+FTKKEP+G C II PWNYPLMMLAWK AACLAAGNT+VLKPAQVTPL +LKF EL+V+AGFP GVIN++PGSG +AG +S+HPDIRKLGFTGST++G+ IM SCA SNLKK SLELGGKSPLIIFSDCD++KAV+ +VFFNKGENCIAAGR+FV+ IHD F+ VVE++KKMKIGDPLDRS DHGPQNH HL KLL++C+ GV+EGA LV+GG++ R G+FMEPT+FT V D MY+A+EESFGPIM+ISKF DID V+ RAN TEYGLASGVFT DI+KA+ V+D ++AGTVFINTYNKTDVAAPFGG KQSGFGKDLG+EALNEYLK KTVT+EY
Sbjct: 65 ALAAEKDGTPVFKFPRWRLKGKTIKEVAEAYQSVGAELNVLPFCTQFIPMDVIDSPKHGSIIYHPSLLPRHRGASAINWTLIMGDKKAGFSVFWADDGLDTGPILLQRSCDVKPNDTVDSLYNRFLFPEGIKAMVEAVQLIADGKAPRTPQPEEGATYEGIQKKENAEVSWDQPAEGLHNWIRGHDKVPGAWAEINGQMVTFYGSSLLTSSV-PSGEPLDIRGAKKPGLVTKNGLVLFGNDGKALMVRNLQFED-GKMIPASQYFSAGE-TSVVELTAEELKVAETIKVIWARILSNTPVIEDSTDFFKSGASSMDVVRLVEEIRQSCG-GLQLQNEDVYMATKFGDFIQKVVRRLRGEDEEAEMVVDYVSKEVNGMTVKIPYQCFINGQFVDAEDGETYATVNPTDGTTICRVSYASLADVDRAVAAAKDAFENGEWGRMNARDRGRLMYRLADLMEENQEELATIEALDSGAVYTLALKTHIGMSVQTFRYFAGWCDKIQGSTIPINQARPNYNLTFTKKEPLGACAIIIPWNYPLMMLAWKSAACLAAGNTLVLKPAQVTPLTALKFAELTVKAGFPKGVINIIPGSGGVAGQRLSQHPDIRKLGFTGSTSVGKQIMKSCAVSNLKKVSLELGGKSPLIIFSDCDLEKAVRMGMGAVFFNKGENCIAAGRLFVEEAIHDEFVTRVVEEIKKMKIGDPLDRSTDHGPQNHRAHLEKLLQYCETGVQEGATLVYGGRQVQRPGFFMEPTVFTGVEDHMYLAKEESFGPIMVISKFQNGDIDGVLQRANNTEYGLASGVFTRDINKAMYVSDKLEAGTVFINTYNKTDVAAPFGGMKQSGFGKDLGEEALNEYLKIKTVTLEY 923 HSP 2 Score: 69.707 bits (169), Expect = 1.980e-11 Identity = 26/48 (54.17%), Postives = 40/48 (83.33%), Query Frame = 1
Query: 103 FNPRMKIAIIGQSIFGAQVYKELKNEGHDIVGVFTIPDRNGRSDPLGI 246
F ++K+A+IGQS+FG +VY +L EGH +VGVFT+PD++G++DPL +
Sbjct: 19 FKNKLKLALIGQSLFGQEVYSQLLKEGHRVVGVFTVPDKDGKADPLAL 66
BLAST of 10-formyltetrahydrofolate dehydrogenase vs. Ensembl Mouse
Match: Aldh1l1 (aldehyde dehydrogenase 1 family, member L1 [Source:MGI Symbol;Acc:MGI:1340024]) HSP 1 Score: 1064.68 bits (2752), Expect = 0.000e+0 Identity = 521/863 (60.37%), Postives = 664/863 (76.94%), Query Frame = 3
Query: 438 AMEAIDLGTKVFKIPKWRVNNQIIKEVFEEYRSINAELNVLAFCTQFIPMEVINAPKHRSIIYHPSLLPKHRGASAINWTLINGDLKGGLTIFWADDGLDTGPVLLQRECDVHINDTVDSLYSRFMMPEGIKAMVEAVRQIESGRAPAIAQYHPDHSYDQMVKKSTAEINWNQSGLSLHNFIRGHDKVPGAWSWINGQKVTFYGSQLWYHDVVHDGPSLAIQGLSDPAVLHNHGLLIRGSDNQWINIAQLKFEDTGKTVQASKYGKGDEITTMADLSEDERAMEIPLMKIWKSILMG-SDIEPESDFFKLGGTSMDVTRIIEQIK--CNFNVELKIDHIYLYSTFDTLFKWIVLRKRGGGSQKKLHYDAVIINANKMTFPIPHQIFINNEFVNSESGKEYDSKNPSDESVICRVSYSSXXXXXXXXXXXXXXFEFGEWGKMSARDRGRILYKLADLMEEHAEELATLESLDSGAVYTLALKTHIGMSIETFRYFAGWCDKIQGSTIPISNARPNKNLSFTKKEPIGVCGIITPWNYPLMMLAWKVAACLAAGNTVVLKPAQVTPLASLKFCELSVEAGFPPGVINVLPGSGAIAGTAISEHPDIRKLGFTGSTAIGQTIMSSCAKSNLKKCSLELGGKSPLIIFSDCDMDKAVKSACSSVFFNKGENCIAAGRIFVDVRIHDVFLKLVVEDVKKMKIGDPLDRSVDHGPQNHEIHLLKLLEFCDIGVKEGAKLVFGGKRCDRKGYFMEPTIFTSVTDDMYIAREESFGPIMIISKFY--DIDEVIVRANKTEYGLASGVFTNDISKALRVADAIDAGTVFINTYNKTDVAAPFGGFKQSGFGKDLGQEALNEYLKTKTVTVEY 3011
+EA G VFK P+WR Q + EV +Y+++ AELNVL FC+QFIPMEVINAP+H SIIYHPSLLP+HRGASAINWTLI+GD KGG TIFWADDGLDTG +LLQ+ECDV +DTV +LY+RF+ PEGIK MV+AVR I G AP Q +Y+ + KK TA INW+Q ++HN+IRG+DKVPGAW+ GQK+TF+ S L +V G +L I G P ++ GL++ G+D++ + + ++ ED GK + AS++ KG + + +L+E+E A + W IL ++E +DFFK G S+DV R++E++K C+ +EL+ + +Y+ +TF + +V + RG + + + V K+T +P+Q+FI EFV++E K Y + NP+D SVIC+VS + DVD AV AAKEAFE G WGK++ARDRGR+LY+LADLME+H EELAT+E+LD+GAVYTLALKTH+GMSI+TFRYFAGWCDKIQG+TIPI+ ARPN+NL+ TKKEP+GVCGI+ PWNYPLMML+WK AACLAAGNTVV+KPAQVTPL +LKF EL+++AG P GV+N+LPGSG++ G +S+HPD+RK+GFTGST +G+ IM SCA SN+KK SLELGGKSPLIIF+DCD++KAV+ SSVFFNKGENCIAAGR+FV+ IHD F++ VVE+V KMKIG+PLDR +HGPQNHE HL KL+E+C GVKEGA LV GG + R G+F +PT+FT V D MYIA+EESFGPIMIIS+F D+D V+ RAN TE+GLASGVFT DI+KAL V+D + AGTVF+NTYNKTDVAAPFGGFKQSGFGKDLG+ ALNEYL+ KTVT EY
Sbjct: 43 GLEAEKDGVPVFKFPRWRARGQALPEVVAKYQALGAELNVLPFCSQFIPMEVINAPRHGSIIYHPSLLPRHRGASAINWTLIHGDKKGGFTIFWADDGLDTGDLLLQKECDVLPDDTVSTLYNRFLFPEGIKGMVQAVRLIAEGTAPRRPQPEEGATYEGIQKKETAMINWDQPAEAIHNWIRGNDKVPGAWTEACGQKLTFFNSTLNTSGLVAQGEALPIPGAHRPGLVTKAGLILFGNDDRMLLVKNIQLED-GKMMPASQFFKGSASSAL-ELTEEELATAEAVRSSWMRILPNVPEVEDSTDFFKSGAASVDVVRLVEEVKELCD-GLELENEDVYMATTFGDFIQLLVRKLRGEDGESECVINYVEKAVKKLTLQMPYQLFIGGEFVDAEGAKTYSTINPTDGSVICQVSLAQVSDVDKAVAAAKEAFENGLWGKINARDRGRLLYRLADLMEQHQEELATIEALDAGAVYTLALKTHVGMSIQTFRYFAGWCDKIQGATIPINQARPNRNLTLTKKEPVGVCGIVIPWNYPLMMLSWKTAACLAAGNTVVIKPAQVTPLTALKFAELTLKAGIPKGVVNILPGSGSLVGQRLSDHPDVRKIGFTGSTEVGKHIMKSCALSNVKKVSLELGGKSPLIIFADCDLNKAVQMGMSSVFFNKGENCIAAGRLFVEDSIHDQFVQKVVEEVGKMKIGNPLDRDTNHGPQNHEAHLRKLVEYCQRGVKEGATLVCGGNQVPRPGFFFQPTVFTDVEDHMYIAKEESFGPIMIISRFADGDVDAVLSRANATEFGLASGVFTRDINKALYVSDKLQAGTVFVNTYNKTDVAAPFGGFKQSGFGKDLGEAALNEYLRIKTVTFEY 902 HSP 2 Score: 73.9442 bits (180), Expect = 8.848e-13 Identity = 32/68 (47.06%), Postives = 50/68 (73.53%), Query Frame = 1
Query: 115 MKIAIIGQSIFGAQVYKELKNEGHDIVGVFTIPDRNGRSDPLGIFYWE*GFTTLLMTSKKSQGRPLAQ 318
MKIA+IGQS+FG +VY +L+ EGH++VGVFTIPD++G++DPLG+ + G +++G+ L +
Sbjct: 1 MKIAVIGQSLFGQEVYCQLRKEGHEVVGVFTIPDKDGKADPLGLEAEKDGVPVFKFPRWRARGQALPE 68
BLAST of 10-formyltetrahydrofolate dehydrogenase vs. Ensembl Mouse
Match: Aldh1l1 (aldehyde dehydrogenase 1 family, member L1 [Source:MGI Symbol;Acc:MGI:1340024]) HSP 1 Score: 1064.68 bits (2752), Expect = 0.000e+0 Identity = 521/863 (60.37%), Postives = 664/863 (76.94%), Query Frame = 3
Query: 438 AMEAIDLGTKVFKIPKWRVNNQIIKEVFEEYRSINAELNVLAFCTQFIPMEVINAPKHRSIIYHPSLLPKHRGASAINWTLINGDLKGGLTIFWADDGLDTGPVLLQRECDVHINDTVDSLYSRFMMPEGIKAMVEAVRQIESGRAPAIAQYHPDHSYDQMVKKSTAEINWNQSGLSLHNFIRGHDKVPGAWSWINGQKVTFYGSQLWYHDVVHDGPSLAIQGLSDPAVLHNHGLLIRGSDNQWINIAQLKFEDTGKTVQASKYGKGDEITTMADLSEDERAMEIPLMKIWKSILMG-SDIEPESDFFKLGGTSMDVTRIIEQIK--CNFNVELKIDHIYLYSTFDTLFKWIVLRKRGGGSQKKLHYDAVIINANKMTFPIPHQIFINNEFVNSESGKEYDSKNPSDESVICRVSYSSXXXXXXXXXXXXXXFEFGEWGKMSARDRGRILYKLADLMEEHAEELATLESLDSGAVYTLALKTHIGMSIETFRYFAGWCDKIQGSTIPISNARPNKNLSFTKKEPIGVCGIITPWNYPLMMLAWKVAACLAAGNTVVLKPAQVTPLASLKFCELSVEAGFPPGVINVLPGSGAIAGTAISEHPDIRKLGFTGSTAIGQTIMSSCAKSNLKKCSLELGGKSPLIIFSDCDMDKAVKSACSSVFFNKGENCIAAGRIFVDVRIHDVFLKLVVEDVKKMKIGDPLDRSVDHGPQNHEIHLLKLLEFCDIGVKEGAKLVFGGKRCDRKGYFMEPTIFTSVTDDMYIAREESFGPIMIISKFY--DIDEVIVRANKTEYGLASGVFTNDISKALRVADAIDAGTVFINTYNKTDVAAPFGGFKQSGFGKDLGQEALNEYLKTKTVTVEY 3011
+EA G VFK P+WR Q + EV +Y+++ AELNVL FC+QFIPMEVINAP+H SIIYHPSLLP+HRGASAINWTLI+GD KGG TIFWADDGLDTG +LLQ+ECDV +DTV +LY+RF+ PEGIK MV+AVR I G AP Q +Y+ + KK TA INW+Q ++HN+IRG+DKVPGAW+ GQK+TF+ S L +V G +L I G P ++ GL++ G+D++ + + ++ ED GK + AS++ KG + + +L+E+E A + W IL ++E +DFFK G S+DV R++E++K C+ +EL+ + +Y+ +TF + +V + RG + + + V K+T +P+Q+FI EFV++E K Y + NP+D SVIC+VS + DVD AV AAKEAFE G WGK++ARDRGR+LY+LADLME+H EELAT+E+LD+GAVYTLALKTH+GMSI+TFRYFAGWCDKIQG+TIPI+ ARPN+NL+ TKKEP+GVCGI+ PWNYPLMML+WK AACLAAGNTVV+KPAQVTPL +LKF EL+++AG P GV+N+LPGSG++ G +S+HPD+RK+GFTGST +G+ IM SCA SN+KK SLELGGKSPLIIF+DCD++KAV+ SSVFFNKGENCIAAGR+FV+ IHD F++ VVE+V KMKIG+PLDR +HGPQNHE HL KL+E+C GVKEGA LV GG + R G+F +PT+FT V D MYIA+EESFGPIMIIS+F D+D V+ RAN TE+GLASGVFT DI+KAL V+D + AGTVF+NTYNKTDVAAPFGGFKQSGFGKDLG+ ALNEYL+ KTVT EY
Sbjct: 43 GLEAEKDGVPVFKFPRWRARGQALPEVVAKYQALGAELNVLPFCSQFIPMEVINAPRHGSIIYHPSLLPRHRGASAINWTLIHGDKKGGFTIFWADDGLDTGDLLLQKECDVLPDDTVSTLYNRFLFPEGIKGMVQAVRLIAEGTAPRRPQPEEGATYEGIQKKETAMINWDQPAEAIHNWIRGNDKVPGAWTEACGQKLTFFNSTLNTSGLVAQGEALPIPGAHRPGLVTKAGLILFGNDDRMLLVKNIQLED-GKMMPASQFFKGSASSAL-ELTEEELATAEAVRSSWMRILPNVPEVEDSTDFFKSGAASVDVVRLVEEVKELCD-GLELENEDVYMATTFGDFIQLLVRKLRGEDGESECVINYVEKAVKKLTLQMPYQLFIGGEFVDAEGAKTYSTINPTDGSVICQVSLAQVSDVDKAVAAAKEAFENGLWGKINARDRGRLLYRLADLMEQHQEELATIEALDAGAVYTLALKTHVGMSIQTFRYFAGWCDKIQGATIPINQARPNRNLTLTKKEPVGVCGIVIPWNYPLMMLSWKTAACLAAGNTVVIKPAQVTPLTALKFAELTLKAGIPKGVVNILPGSGSLVGQRLSDHPDVRKIGFTGSTEVGKHIMKSCALSNVKKVSLELGGKSPLIIFADCDLNKAVQMGMSSVFFNKGENCIAAGRLFVEDSIHDQFVQKVVEEVGKMKIGNPLDRDTNHGPQNHEAHLRKLVEYCQRGVKEGATLVCGGNQVPRPGFFFQPTVFTDVEDHMYIAKEESFGPIMIISRFADGDVDAVLSRANATEFGLASGVFTRDINKALYVSDKLQAGTVFVNTYNKTDVAAPFGGFKQSGFGKDLGEAALNEYLRIKTVTFEY 902 HSP 2 Score: 73.9442 bits (180), Expect = 8.848e-13 Identity = 32/68 (47.06%), Postives = 50/68 (73.53%), Query Frame = 1
Query: 115 MKIAIIGQSIFGAQVYKELKNEGHDIVGVFTIPDRNGRSDPLGIFYWE*GFTTLLMTSKKSQGRPLAQ 318
MKIA+IGQS+FG +VY +L+ EGH++VGVFTIPD++G++DPLG+ + G +++G+ L +
Sbjct: 1 MKIAVIGQSLFGQEVYCQLRKEGHEVVGVFTIPDKDGKADPLGLEAEKDGVPVFKFPRWRARGQALPE 68
BLAST of 10-formyltetrahydrofolate dehydrogenase vs. Ensembl Mouse
Match: Aldh1l2 (aldehyde dehydrogenase 1 family, member L2 [Source:MGI Symbol;Acc:MGI:2444680]) HSP 1 Score: 1058.13 bits (2735), Expect = 0.000e+0 Identity = 519/814 (63.76%), Postives = 641/814 (78.75%), Query Frame = 3
Query: 585 MEVINAPKHRSIIYHPSLLPKHRGASAINWTLINGDLKGGLTIFWADDGLDTGPVLLQRECDVHINDTVDSLYSRFMMPEGIKAMVEAVRQIESGRAPAIAQYHPDHSYDQMVKKSTAEINWNQSGLSLHNFIRGHDKVPGAWSWINGQKVTFYGSQLWYHDVVHDGPSLAIQGLSDPAVLHNHGLLIRGSDNQWINIAQLKFEDTGKTVQASKYGKGDEITTMADLSEDERAMEIPLMKIWKSILMGSD-IEPESDFFKLGGTSMDVTRIIEQIK--CNFNVELKIDHIYLYSTFDTLFKWIVLRKRGGGSQKKLHYDAVIINANKMTFPIPHQIFINNEFVNSESGKEYDSKNPSDESVICRVSYSSXXXXXXXXXXXXXXFEFGEWGKMSARDRGRILYKLADLMEEHAEELATLESLDSGAVYTLALKTHIGMSIETFRYFAGWCDKIQGSTIPISNARPNKNLSFTKKEPIGVCGIITPWNYPLMMLAWKVAACLAAGNTVVLKPAQVTPLASLKFCELSVEAGFPPGVINVLPGSGAIAGTAISEHPDIRKLGFTGSTAIGQTIMSSCAKSNLKKCSLELGGKSPLIIFSDCDMDKAVKSACSSVFFNKGENCIAAGRIFVDVRIHDVFLKLVVEDVKKMKIGDPLDRSVDHGPQNHEIHLLKLLEFCDIGVKEGAKLVFGGKRCDRKGYFMEPTIFTSVTDDMYIAREESFGPIMIISKFY--DIDEVIVRANKTEYGLASGVFTNDISKALRVADAIDAGTVFINTYNKTDVAAPFGGFKQSGFGKDLGQEALNEYLKTKTVTVEY 3011
M+VI++PKH SIIYHPSLLP+HRGASAINWTLI GD K G ++FWADDGLDTGP+LLQR CDV NDTVDSLY+RF+ PEGIKAMVEAV+ I G+AP Q +Y+ + KK AE++W+Q LHN+IRGHDKVPGAW+ INGQ VTFYGS L V G L I+G P ++ +GL++ G+D + + + L+FED GK + AS+Y E T++ +L+ +E + + IW IL + IE +DFFK G +SMDV R++E+I+ C ++L+ + +Y+ + F + +V R RG + ++ D V N MT IP+Q FIN +FV++E G+ Y + NP+D + ICRVSY+S DVD AV AAK+AFE GEWG+M+ARDRGR++Y+LADLMEE+ EELAT+E+LDSGAVYTLALKTHIGMS++TFRYFAGWCDKIQGSTIPI+ ARPN NL+FTKKEP+G C II PWNYPLMMLAWK AACLAAGNT+VLKPAQVTPL +LKF EL+V+AGFP GVIN++PGSG +AG +S+HPDIRKLGFTGST++G+ IM SCA SNLKK SLELGGKSPLIIFSDCD++KAV+ +VFFNKGENCIAAGR+FV+ IHD F+ VVE++KKMKIGDPLDRS DHGPQNH HL KLL++C+ GV+EGA LV+GG++ R G+FMEPT+FT V D MY+A+EESFGPIM+ISKF DID V+ RAN TEYGLASGVFT DI+KA+ V+D ++AGTVFINTYNKTDVAAPFGG KQSGFGKDLG+EALNEYLK KTVT+EY
Sbjct: 1 MDVIDSPKHGSIIYHPSLLPRHRGASAINWTLIMGDKKAGFSVFWADDGLDTGPILLQRSCDVKPNDTVDSLYNRFLFPEGIKAMVEAVQLIADGKAPRTPQPEEGATYEGIQKKENAEVSWDQPAEGLHNWIRGHDKVPGAWAEINGQMVTFYGSSLLTSSV-PSGEPLDIRGAKKPGLVTKNGLVLFGNDGKALMVRNLQFED-GKMIPASQYFSAGE-TSVVELTAEELKVAETIKVIWARILSNTPVIEDSTDFFKSGASSMDVVRLVEEIRQSCG-GLQLQNEDVYMATKFGDFIQKVVRRLRGEDEEAEMVVDYVSKEVNGMTVKIPYQCFINGQFVDAEDGETYATVNPTDGTTICRVSYASLADVDRAVAAAKDAFENGEWGRMNARDRGRLMYRLADLMEENQEELATIEALDSGAVYTLALKTHIGMSVQTFRYFAGWCDKIQGSTIPINQARPNYNLTFTKKEPLGACAIIIPWNYPLMMLAWKSAACLAAGNTLVLKPAQVTPLTALKFAELTVKAGFPKGVINIIPGSGGVAGQRLSQHPDIRKLGFTGSTSVGKQIMKSCAVSNLKKVSLELGGKSPLIIFSDCDLEKAVRMGMGAVFFNKGENCIAAGRLFVEEAIHDEFVTRVVEEIKKMKIGDPLDRSTDHGPQNHRAHLEKLLQYCETGVQEGATLVYGGRQVQRPGFFMEPTVFTGVEDHMYLAKEESFGPIMVISKFQNGDIDGVLQRANNTEYGLASGVFTRDINKAMYVSDKLEAGTVFINTYNKTDVAAPFGGMKQSGFGKDLGEEALNEYLKIKTVTLEY 810
BLAST of 10-formyltetrahydrofolate dehydrogenase vs. Ensembl Mouse
Match: Aldh1a2 (aldehyde dehydrogenase family 1, subfamily A2 [Source:MGI Symbol;Acc:MGI:107928]) HSP 1 Score: 474.937 bits (1221), Expect = 9.056e-156 Identity = 245/478 (51.26%), Postives = 325/478 (67.99%), Query Frame = 3
Query: 1578 QIFINNEFVNSESGKEYDSKNPSDESVICRVSYSSXXXXXXXXXXXXXXFEFGE-WGKMSARDRGRILYKLADLMEEHAEELATLESLDSGAVYTLALKTHIGMSIETFRYFAGWCDKIQGSTIPISNARPNKNLSFTKKEPIGVCGIITPWNYPLMMLAWKVAACLAAGNTVVLKPAQVTPLASLKFCELSVEAGFPPGVINVLPGSGAIAGTAISEHPDIRKLGFTGSTAIGQTIMSSCAKSNLKKCSLELGGKSPLIIFSDCDMDKAVKSACSSVFFNKGENCIAAGRIFVDVRIHDVFLKLVVEDVKKMKIGDPLDRSVDHGPQNHEIHLLKLLEFCDIGVKEGAKLVFGGKRCDRKGYFMEPTIFTSVTDDMYIAREESFGPIMIISKFYDIDEVIVRANKTEYGLASGVFTNDISKALRVADAIDAGTVFINTYNKTDVAAPFGGFKQSGFGKDLGQEALNEYLKTKTVTVE 3008
+IFINNE+ NSESG+ + NP+ +C V + K D+D AV+AA+ AF G W +M A +RGR+L KLADL+E LAT+ESL+ G + A + I+T RY+AGW DKI G TIP+ +FT+ EPIGVCG I PWN+PL+M WK+A L GNTVV+KPA+ TPL++L L EAGFPPGV+N+LPG G AG AI+ H I K+ FTGST +G+ I + +SNLK+ +LELGGKSP IIF+D D+D AV+ A VFFN+G+ C A RIFV+ I++ F+K VE K+ +G P D + + GPQ + K+LE GV EGAKL GGK RKG+F+EPT+F++VTDDM IA+EE FGP+ I +F +DEVI RAN +++GL + VFTNDI+KAL V+ A+ AGTV+IN YN + +PFGGFK SG G+++G+ L EY + KTVTV+
Sbjct: 39 KIFINNEWQNSESGRVFPVCNPATGEQVCEVQEADKVDIDKAVQAARLAFSLGSVWRRMDASERGRLLDKLADLVERDRATLATMESLNGGKPFLQAFYIDLQGVIKTLRYYAGWADKIHGMTIPVDG----DYFTFTRHEPIGVCGQIIPWNFPLLMFTWKIAPALCCGNTVVIKPAEQTPLSALYMGALIKEAGFPPGVVNILPGYGPTAGAAIASHIGIDKIAFTGSTEVGKLIQEAAGRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFVEESIYEEFVKRSVERAKRRIVGSPFDPTTEQGPQIDKKQYNKVLELIQSGVAEGAKLECGGKGLGRKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLVAAVFTNDINKALMVSSAMQAGTVWINCYNALNAQSPFGGFKMSGNGREMGEFGLREYSEVKTVTVK 512
BLAST of 10-formyltetrahydrofolate dehydrogenase vs. UniProt/SwissProt
Match: sp|Q63ZT8|AL1L1_XENTR (Cytosolic 10-formyltetrahydrofolate dehydrogenase OS=Xenopus tropicalis OX=8364 GN=aldh1l1 PE=2 SV=1) HSP 1 Score: 1129.39 bits (2920), Expect = 0.000e+0 Identity = 546/855 (63.86%), Postives = 675/855 (78.95%), Query Frame = 3
Query: 459 GTKVFKIPKWRVNNQIIKEVFEEYRSINAELNVLAFCTQFIPMEVINAPKHRSIIYHPSLLPKHRGASAINWTLINGDLKGGLTIFWADDGLDTGPVLLQRECDVHINDTVDSLYSRFMMPEGIKAMVEAVRQIESGRAPAIAQYHPDHSYDQMVKKSTAEINWNQSGLSLHNFIRGHDKVPGAWSWINGQKVTFYGSQLWYHDVVHDGPSLAIQGLSDPAVLHNHGLLIRGSDNQWINIAQLKFEDTGKTVQASKYGKGDEITTMADLSEDERAMEIPLMKIWKSILMG-SDIEPESDFFKLGGTSMDVTRIIEQIKCNFN-VELKIDHIYLYSTFDTLFKWIVLRKRGGGSQKKLHYDAVIINANKMTFPIPHQIFINNEFVNSESGKEYDSKNPSDESVICRVSYSSXXXXXXXXXXXXXXFEFGEWGKMSARDRGRILYKLADLMEEHAEELATLESLDSGAVYTLALKTHIGMSIETFRYFAGWCDKIQGSTIPISNARPNKNLSFTKKEPIGVCGIITPWNYPLMMLAWKVAACLAAGNTVVLKPAQVTPLASLKFCELSVEAGFPPGVINVLPGSGAIAGTAISEHPDIRKLGFTGSTAIGQTIMSSCAKSNLKKCSLELGGKSPLIIFSDCDMDKAVKSACSSVFFNKGENCIAAGRIFVDVRIHDVFLKLVVEDVKKMKIGDPLDRSVDHGPQNHEIHLLKLLEFCDIGVKEGAKLVFGGKRCDRKGYFMEPTIFTSVTDDMYIAREESFGPIMIISKFY--DIDEVIVRANKTEYGLASGVFTNDISKALRVADAIDAGTVFINTYNKTDVAAPFGGFKQSGFGKDLGQEALNEYLKTKTVTVEY 3011
G VFK P+WRV Q I EV E+Y+++ AELNVL FC+QFIPMEVI+ PKH SIIYHPS+LP+HRGASAINWTL+ GD GG TIFWADDGLDTG +LLQREC+V +DTV+++Y+RF+ PEG+K MVEAVR I G AP I Q +YD M KK A+INW+Q ++HNFIRG+DKVPGAW+ + Q++TF+GS + DG L I G PAV+ GL++ G+D Q +++ ++FED GK + AS+Y K + + LS++E+ + WK IL S+IE +DFFK G SMDV R++E++K N ++L+ + +Y+ + F+ + +V R RG +++L D V N MT IPHQ+FIN +F+++E GK YD+ NP+D + IC+VS + D+D AV AAKEAFE GEWGKM+ RDRGRILY+LAD+MEEH EELAT+ES+DSGAVYTLALKTH+GMSI+TFRYFAGWCDKIQGSTIPI+ ARPN+NL+FT++EPIGVCGI+ PWNYPLMMLAWK AACLAAGNTVVLKPAQVTPL +LKF ELSV+AG P GVIN+LPG+G++ G +S+HPD+RK+GFTGST IG+ IM SCA N+KK SLELGGKSPLIIF DCD+DKAV+ SSVFFNKGENCIAAGR+F++ IHD F+K VV +VKKMKIGDPLDRS DHGPQNH+ HL KL+E+C GVKEGAKLV+GGK+ +R G+F EPTIFT VTD+M+IA+EESFGPIMIISKF D+DEV+ RAN TE+GLASGVFT DISKAL V++ + AGTVF+NTYNKTDVAAPFGGFKQSGFGKDLG+EALNEYLKTK VT+EY
Sbjct: 50 GIPVFKFPRWRVKGQAIPEVVEKYKALEAELNVLPFCSQFIPMEVIDCPKHGSIIYHPSILPRHRGASAINWTLMQGDKIGGFTIFWADDGLDTGDILLQRECEVLPDDTVNTIYNRFLFPEGVKGMVEAVRLIAEGNAPRIKQATEGATYDPMQKKENAKINWDQPAEAIHNFIRGNDKVPGAWTVVGDQQLTFFGSSFISNGPAPDGQPLEIPGAFRPAVVTKTGLVLFGNDGQKLSVKNIQFED-GKMIPASQYYKTADSAAL-QLSDEEKKFSEEIRAAWKRILTNVSEIEDSTDFFKAGAASMDVVRLVEEVKLKCNGLQLQNEDVYMATKFEEFIQMVVRRLRGEDGEEELVVDYVEKEINNMTVKIPHQLFINGQFIDAEGGKTYDTVNPTDGTAICKVSLAQVSDIDRAVAAAKEAFENGEWGKMNPRDRGRILYRLADIMEEHQEELATIESIDSGAVYTLALKTHVGMSIQTFRYFAGWCDKIQGSTIPINQARPNRNLTFTRREPIGVCGIVIPWNYPLMMLAWKTAACLAAGNTVVLKPAQVTPLTALKFAELSVKAGIPKGVINILPGAGSLIGQRLSDHPDVRKIGFTGSTPIGKHIMKSCAVGNVKKVSLELGGKSPLIIFQDCDLDKAVRMGMSSVFFNKGENCIAAGRLFLEESIHDEFVKRVVGEVKKMKIGDPLDRSTDHGPQNHKAHLDKLIEYCQTGVKEGAKLVYGGKQVERPGFFFEPTIFTDVTDEMFIAKEESFGPIMIISKFKDGDVDEVLKRANNTEFGLASGVFTKDISKALYVSEKLQAGTVFVNTYNKTDVAAPFGGFKQSGFGKDLGEEALNEYLKTKAVTIEY 902 HSP 2 Score: 76.6406 bits (187), Expect = 9.673e-13 Identity = 31/43 (72.09%), Postives = 39/43 (90.70%), Query Frame = 1
Query: 115 MKIAIIGQSIFGAQVYKELKNEGHDIVGVFTIPDRNGRSDPLG 243
MKIA+IGQS+FG +VY+EL EGH +VGVFTIPD+NG++DPLG
Sbjct: 1 MKIAVIGQSLFGREVYRELLKEGHQVVGVFTIPDKNGKADPLG 43
BLAST of 10-formyltetrahydrofolate dehydrogenase vs. UniProt/SwissProt
Match: sp|Q3SY69|AL1L2_HUMAN (Mitochondrial 10-formyltetrahydrofolate dehydrogenase OS=Homo sapiens OX=9606 GN=ALDH1L2 PE=1 SV=2) HSP 1 Score: 1125.15 bits (2909), Expect = 0.000e+0 Identity = 552/863 (63.96%), Postives = 684/863 (79.26%), Query Frame = 3
Query: 438 AMEAIDLGTKVFKIPKWRVNNQIIKEVFEEYRSINAELNVLAFCTQFIPMEVINAPKHRSIIYHPSLLPKHRGASAINWTLINGDLKGGLTIFWADDGLDTGPVLLQRECDVHINDTVDSLYSRFMMPEGIKAMVEAVRQIESGRAPAIAQYHPDHSYDQMVKKSTAEINWNQSGLSLHNFIRGHDKVPGAWSWINGQKVTFYGSQLWYHDVVHDGPSLAIQGLSDPAVLHNHGLLIRGSDNQWINIAQLKFEDTGKTVQASKYGKGDEITTMADLSEDERAMEIPLMKIWKSILMGSDI-EPESDFFKLGGTSMDVTRIIEQI--KCNFNVELKIDHIYLYSTFDTLFKWIVLRKRGGGSQKKLHYDAVIINANKMTFPIPHQIFINNEFVNSESGKEYDSKNPSDESVICRVSYSSXXXXXXXXXXXXXXFEFGEWGKMSARDRGRILYKLADLMEEHAEELATLESLDSGAVYTLALKTHIGMSIETFRYFAGWCDKIQGSTIPISNARPNKNLSFTKKEPIGVCGIITPWNYPLMMLAWKVAACLAAGNTVVLKPAQVTPLASLKFCELSVEAGFPPGVINVLPGSGAIAGTAISEHPDIRKLGFTGSTAIGQTIMSSCAKSNLKKCSLELGGKSPLIIFSDCDMDKAVKSACSSVFFNKGENCIAAGRIFVDVRIHDVFLKLVVEDVKKMKIGDPLDRSVDHGPQNHEIHLLKLLEFCDIGVKEGAKLVFGGKRCDRKGYFMEPTIFTSVTDDMYIAREESFGPIMIISKFY--DIDEVIVRANKTEYGLASGVFTNDISKALRVADAIDAGTVFINTYNKTDVAAPFGGFKQSGFGKDLGQEALNEYLKTKTVTVEY 3011
A+ A GT VFK+PKWRV + IKEV E YRS+ AELNVL FCTQFIPM++I++PKH SIIYHPS+LP+HRGASAINWTLI GD K G ++FWADDGLDTGP+LLQR CDV NDTVD+LY+RF+ PEGIKAMVEAV+ I G+AP I Q +Y+ + KK AEI+W+QS LHN+IRGHDKVPGAW+ INGQ VTFYGS L + V G L I+G P ++ +GL++ G+D + + + L+FED GK + AS+Y E T++ +L+ +E + + IW IL I E +DFFK G +SMDV R++E+I KC ++L+ + +Y+ + F+ + +V + RG + +L D + N++ +P+Q FIN +F +++ GK YD+ NP+D S IC+VSY+S DVD AV AAK+AFE GEWG+M+AR+RGR++Y+LADL+EE+ EELAT+E+LDSGAVYTLALKTHIGMS++TFRYFAGWCDKIQGSTIPI+ ARPN+NL+FTKKEP+GVC II PWNYPLMMLAWK AACLAAGNT+VLKPAQVTPL +LKF ELSV+AGFP GVIN++PGSG IAG +SEHPDIRKLGFTGST IG+ IM SCA SNLKK SLELGGKSPLIIF+DC++DKAV+ +VFFNKGENCIAAGR+FV+ IHD F+ VVE++KKMKIGDPLDRS DHGPQNH+ HL KLL++C+ GVKEGA LV+GG++ R G+FMEPT+FT V D MY+A+EESFGPIM+ISKF DID V+ RAN TEYGLASGVFT DI+KA+ V++ ++AGTVFINTYNKTDVAAPFGG KQSGFGKDLG+EALNEYLKTKTVT+EY
Sbjct: 65 ALAAEKDGTPVFKLPKWRVKGKTIKEVAEAYRSVGAELNVLPFCTQFIPMDIIDSPKHGSIIYHPSILPRHRGASAINWTLIMGDKKAGFSVFWADDGLDTGPILLQRSCDVEPNDTVDALYNRFLFPEGIKAMVEAVQLIADGKAPRIPQPEEGATYEGIQKKENAEISWDQSAEVLHNWIRGHDKVPGAWTEINGQMVTFYGSTL-LNSSVPPGEPLEIKGAKKPGLVTKNGLVLFGNDGKALTVRNLQFED-GKMIPASQYFSTGE-TSVVELTAEEVKVAETIKVIWAGILSNVPIIEDSTDFFKSGASSMDVARLVEEIRQKCG-GLQLQNEDVYMATKFEGFIQKVVRKLRGEDQEVELVVDYISKEVNEIMVKMPYQCFINGQFTDADDGKTYDTINPTDGSTICKVSYASLADVDKAVAAAKDAFENGEWGRMNARERGRLMYRLADLLEENQEELATIEALDSGAVYTLALKTHIGMSVQTFRYFAGWCDKIQGSTIPINQARPNRNLTFTKKEPLGVCAIIIPWNYPLMMLAWKSAACLAAGNTLVLKPAQVTPLTALKFAELSVKAGFPKGVINIIPGSGGIAGQRLSEHPDIRKLGFTGSTPIGKQIMKSCAVSNLKKVSLELGGKSPLIIFNDCELDKAVRMGMGAVFFNKGENCIAAGRLFVEESIHDEFVTRVVEEIKKMKIGDPLDRSTDHGPQNHKAHLEKLLQYCETGVKEGATLVYGGRQVQRPGFFMEPTVFTDVEDYMYLAKEESFGPIMVISKFQNGDIDGVLQRANSTEYGLASGVFTRDINKAMYVSEKLEAGTVFINTYNKTDVAAPFGGVKQSGFGKDLGEEALNEYLKTKTVTLEY 923 HSP 2 Score: 70.8626 bits (172), Expect = 6.442e-11 Identity = 26/48 (54.17%), Postives = 40/48 (83.33%), Query Frame = 1
Query: 103 FNPRMKIAIIGQSIFGAQVYKELKNEGHDIVGVFTIPDRNGRSDPLGI 246
F ++K+A+IGQS+FG +VY L+ EGH +VGVFT+PD++G++DPL +
Sbjct: 19 FKNKLKLALIGQSLFGQEVYSHLRKEGHRVVGVFTVPDKDGKADPLAL 66
BLAST of 10-formyltetrahydrofolate dehydrogenase vs. UniProt/SwissProt
Match: sp|Q8K009|AL1L2_MOUSE (Mitochondrial 10-formyltetrahydrofolate dehydrogenase OS=Mus musculus OX=10090 GN=Aldh1l2 PE=1 SV=2) HSP 1 Score: 1120.92 bits (2898), Expect = 0.000e+0 Identity = 549/863 (63.62%), Postives = 677/863 (78.45%), Query Frame = 3
Query: 438 AMEAIDLGTKVFKIPKWRVNNQIIKEVFEEYRSINAELNVLAFCTQFIPMEVINAPKHRSIIYHPSLLPKHRGASAINWTLINGDLKGGLTIFWADDGLDTGPVLLQRECDVHINDTVDSLYSRFMMPEGIKAMVEAVRQIESGRAPAIAQYHPDHSYDQMVKKSTAEINWNQSGLSLHNFIRGHDKVPGAWSWINGQKVTFYGSQLWYHDVVHDGPSLAIQGLSDPAVLHNHGLLIRGSDNQWINIAQLKFEDTGKTVQASKYGKGDEITTMADLSEDERAMEIPLMKIWKSILMGSD-IEPESDFFKLGGTSMDVTRIIEQIK--CNFNVELKIDHIYLYSTFDTLFKWIVLRKRGGGSQKKLHYDAVIINANKMTFPIPHQIFINNEFVNSESGKEYDSKNPSDESVICRVSYSSXXXXXXXXXXXXXXFEFGEWGKMSARDRGRILYKLADLMEEHAEELATLESLDSGAVYTLALKTHIGMSIETFRYFAGWCDKIQGSTIPISNARPNKNLSFTKKEPIGVCGIITPWNYPLMMLAWKVAACLAAGNTVVLKPAQVTPLASLKFCELSVEAGFPPGVINVLPGSGAIAGTAISEHPDIRKLGFTGSTAIGQTIMSSCAKSNLKKCSLELGGKSPLIIFSDCDMDKAVKSACSSVFFNKGENCIAAGRIFVDVRIHDVFLKLVVEDVKKMKIGDPLDRSVDHGPQNHEIHLLKLLEFCDIGVKEGAKLVFGGKRCDRKGYFMEPTIFTSVTDDMYIAREESFGPIMIISKFY--DIDEVIVRANKTEYGLASGVFTNDISKALRVADAIDAGTVFINTYNKTDVAAPFGGFKQSGFGKDLGQEALNEYLKTKTVTVEY 3011
A+ A GT VFK P+WR+ + IKEV E Y+S+ AELNVL FCTQFIPM+VI++PKH SIIYHPSLLP+HRGASAINWTLI GD K G ++FWADDGLDTGP+LLQR CDV NDTVDSLY+RF+ PEGIKAMVEAV+ I G+AP Q +Y+ + KK AE++W+Q LHN+IRGHDKVPGAW+ INGQ VTFYGS L V G L I+G P ++ +GL++ G+D + + + L+FED GK + AS+Y E T++ +L+ +E + + IW IL + IE +DFFK G +SMDV R++E+I+ C ++L+ + +Y+ + F + +V R RG + ++ D V N MT IP+Q FIN +FV++E G+ Y + NP+D + ICRVSY+S DVD AV AAK+AFE GEWG+M+ARDRGR++Y+LADLMEE+ EELAT+E+LDSGAVYTLALKTHIGMS++TFRYFAGWCDKIQGSTIPI+ ARPN NL+FTKKEP+G C II PWNYPLMMLAWK AACLAAGNT+VLKPAQVTPL +LKF EL+V+AGFP GVIN++PGSG +AG +S+HPDIRKLGFTGST++G+ IM SCA SNLKK SLELGGKSPLIIFSDCD++KAV+ +VFFNKGENCIAAGR+FV+ IHD F+ VVE++KKMKIGDPLDRS DHGPQNH HL KLL++C+ GV+EGA LV+GG++ R G+FMEPT+FT V D MY+A+EESFGPIM+ISKF DID V+ RAN TEYGLASGVFT DI+KA+ V+D ++AGTVFINTYNKTDVAAPFGG KQSGFGKDLG+EALNEYLK KTVT+EY
Sbjct: 65 ALAAEKDGTPVFKFPRWRLKGKTIKEVAEAYQSVGAELNVLPFCTQFIPMDVIDSPKHGSIIYHPSLLPRHRGASAINWTLIMGDKKAGFSVFWADDGLDTGPILLQRSCDVKPNDTVDSLYNRFLFPEGIKAMVEAVQLIADGKAPRTPQPEEGATYEGIQKKENAEVSWDQPAEGLHNWIRGHDKVPGAWAEINGQMVTFYGSSLLTSSV-PSGEPLDIRGAKKPGLVTKNGLVLFGNDGKALMVRNLQFED-GKMIPASQYFSAGE-TSVVELTAEELKVAETIKVIWARILSNTPVIEDSTDFFKSGASSMDVVRLVEEIRQSCG-GLQLQNEDVYMATKFGDFIQKVVRRLRGEDEEAEMVVDYVSKEVNGMTVKIPYQCFINGQFVDAEDGETYATVNPTDGTTICRVSYASLADVDRAVAAAKDAFENGEWGRMNARDRGRLMYRLADLMEENQEELATIEALDSGAVYTLALKTHIGMSVQTFRYFAGWCDKIQGSTIPINQARPNYNLTFTKKEPLGACAIIIPWNYPLMMLAWKSAACLAAGNTLVLKPAQVTPLTALKFAELTVKAGFPKGVINIIPGSGGVAGQRLSQHPDIRKLGFTGSTSVGKQIMKSCAVSNLKKVSLELGGKSPLIIFSDCDLEKAVRMGMGAVFFNKGENCIAAGRLFVEEAIHDEFVTRVVEEIKKMKIGDPLDRSTDHGPQNHRAHLEKLLQYCETGVQEGATLVYGGRQVQRPGFFMEPTVFTGVEDHMYLAKEESFGPIMVISKFQNGDIDGVLQRANNTEYGLASGVFTRDINKAMYVSDKLEAGTVFINTYNKTDVAAPFGGMKQSGFGKDLGEEALNEYLKIKTVTLEY 923 HSP 2 Score: 69.707 bits (169), Expect = 1.385e-10 Identity = 26/48 (54.17%), Postives = 40/48 (83.33%), Query Frame = 1
Query: 103 FNPRMKIAIIGQSIFGAQVYKELKNEGHDIVGVFTIPDRNGRSDPLGI 246
F ++K+A+IGQS+FG +VY +L EGH +VGVFT+PD++G++DPL +
Sbjct: 19 FKNKLKLALIGQSLFGQEVYSQLLKEGHRVVGVFTVPDKDGKADPLAL 66
BLAST of 10-formyltetrahydrofolate dehydrogenase vs. UniProt/SwissProt
Match: sp|Q6GNL7|AL1L1_XENLA (Cytosolic 10-formyltetrahydrofolate dehydrogenase OS=Xenopus laevis OX=8355 GN=aldh1l1 PE=2 SV=1) HSP 1 Score: 1120.53 bits (2897), Expect = 0.000e+0 Identity = 539/855 (63.04%), Postives = 674/855 (78.83%), Query Frame = 3
Query: 459 GTKVFKIPKWRVNNQIIKEVFEEYRSINAELNVLAFCTQFIPMEVINAPKHRSIIYHPSLLPKHRGASAINWTLINGDLKGGLTIFWADDGLDTGPVLLQRECDVHINDTVDSLYSRFMMPEGIKAMVEAVRQIESGRAPAIAQYHPDHSYDQMVKKSTAEINWNQSGLSLHNFIRGHDKVPGAWSWINGQKVTFYGSQLWYHDVVHDGPSLAIQGLSDPAVLHNHGLLIRGSDNQWINIAQLKFEDTGKTVQASKYGKGDEITTMADLSEDERAMEIPLMKIWKSILMG-SDIEPESDFFKLGGTSMDVTRIIEQIKCNFN-VELKIDHIYLYSTFDTLFKWIVLRKRGGGSQKKLHYDAVIINANKMTFPIPHQIFINNEFVNSESGKEYDSKNPSDESVICRVSYSSXXXXXXXXXXXXXXFEFGEWGKMSARDRGRILYKLADLMEEHAEELATLESLDSGAVYTLALKTHIGMSIETFRYFAGWCDKIQGSTIPISNARPNKNLSFTKKEPIGVCGIITPWNYPLMMLAWKVAACLAAGNTVVLKPAQVTPLASLKFCELSVEAGFPPGVINVLPGSGAIAGTAISEHPDIRKLGFTGSTAIGQTIMSSCAKSNLKKCSLELGGKSPLIIFSDCDMDKAVKSACSSVFFNKGENCIAAGRIFVDVRIHDVFLKLVVEDVKKMKIGDPLDRSVDHGPQNHEIHLLKLLEFCDIGVKEGAKLVFGGKRCDRKGYFMEPTIFTSVTDDMYIAREESFGPIMIISKFY--DIDEVIVRANKTEYGLASGVFTNDISKALRVADAIDAGTVFINTYNKTDVAAPFGGFKQSGFGKDLGQEALNEYLKTKTVTVEY 3011
G VFK P+WRV Q I EV E+Y+++ AELNVL FC+QFIPMEVI+ PKH SIIYHPS+LP+HRGASAINWTL+ GD GG T+FWADDGLDTG +LLQR+C+V +DTV+++Y+RF+ PEG+K MVEAVR I G AP I Q +YD M KK A+INW+Q +HNFIRG+DKVPGAW+ ++ Q++TF+GS + DG L I G S PA++ GL++ G+D + + + ++FED GK + AS+Y K + + LSE+E+ + + W+ IL S+IE +DFFK G SMDV R++E++K N ++L+ + +Y+ + F+ + +V R RG +++L D V N MT IPHQ+FIN +F+++E GK YD+ NP+D + IC+VS + D+D AV AAKEAFE GEWGKM+ RDRGR+LY+LADLMEEH EELAT+ES+DSGAVYTLALKTH+GMSI+TFRYFAGWCDKIQG TIPI+ ARPN+NL+FT++EPIGVCGI+ PWNYPLMMLAWK AACL AGNTVVLKPAQVTPL +LKF ELSV+AG P GVIN+LPG+G++ G +S+HPD+RK+GFTGST IG+ IM SCA SN+KK SLELGGKSPLIIF DCD+DKAV+ SSVFFNKGENCIAAGR+F++ IHD F+K VVE+VKKMKIGDPLDRS DHGPQNH+ HL KL+E+C GVKEG KLV+GGK+ +R G+F EPTIFT VTD+M+IA+EESFGP+MIISKF DID V+ RAN +E+GLASGVFT DI+KAL V++ + AGTVF+NTYNKTDVAAPFGGFKQSGFGKDLG+EALNEYLKTK VT+EY
Sbjct: 50 GIPVFKFPRWRVKGQAIPEVVEKYKALEAELNVLPFCSQFIPMEVIDCPKHGSIIYHPSILPRHRGASAINWTLMQGDKIGGFTVFWADDGLDTGDILLQRQCEVLPDDTVNTIYNRFLFPEGVKGMVEAVRLIAEGNAPRIKQPTEGATYDPMQKKENAKINWDQPAEDIHNFIRGNDKVPGAWTVVDDQQLTFFGSSFTRNGPAPDGQPLEIPGASRPALVTKTGLVLFGNDGERLTVKNIQFED-GKMIPASQYFKTADSAAL-QLSEEEQKVSEEIRAAWRRILTNVSEIEDSTDFFKAGAASMDVVRLVEEVKLKCNGLQLQNEDVYMATKFEEFIQMVVRRMRGEDGEEELVIDYVEKEINNMTVKIPHQLFINGQFMDAEGGKSYDTINPTDGTAICKVSLAQISDIDRAVAAAKEAFENGEWGKMNPRDRGRLLYRLADLMEEHQEELATIESIDSGAVYTLALKTHVGMSIQTFRYFAGWCDKIQGRTIPINQARPNRNLTFTRREPIGVCGIVIPWNYPLMMLAWKTAACLTAGNTVVLKPAQVTPLTALKFAELSVKAGIPKGVINILPGAGSLIGQRLSDHPDVRKIGFTGSTPIGKQIMKSCAVSNVKKVSLELGGKSPLIIFHDCDLDKAVRMGMSSVFFNKGENCIAAGRLFLEESIHDEFVKRVVEEVKKMKIGDPLDRSTDHGPQNHKAHLDKLIEYCQTGVKEGGKLVYGGKQVERPGFFFEPTIFTDVTDEMFIAKEESFGPVMIISKFNDGDIDGVLKRANDSEFGLASGVFTKDINKALYVSEKLQAGTVFVNTYNKTDVAAPFGGFKQSGFGKDLGEEALNEYLKTKAVTIEY 902 HSP 2 Score: 76.6406 bits (187), Expect = 9.673e-13 Identity = 31/43 (72.09%), Postives = 39/43 (90.70%), Query Frame = 1
Query: 115 MKIAIIGQSIFGAQVYKELKNEGHDIVGVFTIPDRNGRSDPLG 243
MKIA+IGQS+FG +VY+EL EGH +VGVFTIPD+NG++DPLG
Sbjct: 1 MKIAVIGQSLFGREVYRELLKEGHQVVGVFTIPDKNGKADPLG 43
BLAST of 10-formyltetrahydrofolate dehydrogenase vs. UniProt/SwissProt
Match: sp|Q5RFM9|AL1L1_PONAB (Cytosolic 10-formyltetrahydrofolate dehydrogenase OS=Pongo abelii OX=9601 GN=ALDH1L1 PE=2 SV=1) HSP 1 Score: 1072.38 bits (2772), Expect = 0.000e+0 Identity = 521/863 (60.37%), Postives = 668/863 (77.40%), Query Frame = 3
Query: 438 AMEAIDLGTKVFKIPKWRVNNQIIKEVFEEYRSINAELNVLAFCTQFIPMEVINAPKHRSIIYHPSLLPKHRGASAINWTLINGDLKGGLTIFWADDGLDTGPVLLQRECDVHINDTVDSLYSRFMMPEGIKAMVEAVRQIESGRAPAIAQYHPDHSYDQMVKKSTAEINWNQSGLSLHNFIRGHDKVPGAWSWINGQKVTFYGSQLWYHDVVHDGPSLAIQGLSDPAVLHNHGLLIRGSDNQWINIAQLKFEDTGKTVQASKYGKGDEITTMADLSEDERAMEIPLMKIWKSILMGS-DIEPESDFFKLGGTSMDVTRIIEQIK--CNFNVELKIDHIYLYSTFDTLFKWIVLRKRGGGSQKKLHYDAVIINANKMTFPIPHQIFINNEFVNSESGKEYDSKNPSDESVICRVSYSSXXXXXXXXXXXXXXFEFGEWGKMSARDRGRILYKLADLMEEHAEELATLESLDSGAVYTLALKTHIGMSIETFRYFAGWCDKIQGSTIPISNARPNKNLSFTKKEPIGVCGIITPWNYPLMMLAWKVAACLAAGNTVVLKPAQVTPLASLKFCELSVEAGFPPGVINVLPGSGAIAGTAISEHPDIRKLGFTGSTAIGQTIMSSCAKSNLKKCSLELGGKSPLIIFSDCDMDKAVKSACSSVFFNKGENCIAAGRIFVDVRIHDVFLKLVVEDVKKMKIGDPLDRSVDHGPQNHEIHLLKLLEFCDIGVKEGAKLVFGGKRCDRKGYFMEPTIFTSVTDDMYIAREESFGPIMIISKFY--DIDEVIVRANKTEYGLASGVFTNDISKALRVADAIDAGTVFINTYNKTDVAAPFGGFKQSGFGKDLGQEALNEYLKTKTVTVEY 3011
+EA G VFK +WR Q + +V +Y+++ AELNVL FC+QFIPME+INAP+H SIIYHPSLLP+HRGASAINWTLI+GD KGG +IFWADDGLDTG +LLQ+EC+V +DTV +LY+RF+ PEGIK MV+AVR I G+AP + Q +Y+ + KK TA+INW+Q ++HN+IRG+DKVPGAW+ QK+TF+ S L +V +G +L I G P V+ GL++ G+D++ + + ++ ED GK + AS + KG + + +L+E E + +W+ IL ++E +DFFK G S+DV R++E++K C+ +EL+ + +Y+ STF + +V + RG + + D V + NK T IPHQ+FI EFV++E K Y++ NP+D SVIC+VS + DVD AV AAK+AFE G WGK+SARDRGR+LY+LADLME+H EELAT+E+LD+GAVYTLALKTH+GMSI+TFRYFAGWCDKIQGSTIPI+ ARPN+NL+ T+KEP+GVCGII PWNYPLMML+WK AACLAAGNTVV+KPAQVTPL +LKF EL+++AG P GV+NVLPGSG++ G +S+HPD+RK+GFTGST +G+ IM SCA SN+KK SLELGGKSPLIIF+DCD++KAV+ SSVFFNKGENCIAAGR+FV+ IHD F++ VVE+V+KMK+GDPLDR DHGPQNH HL+KL+E+C GVKEGA LV GG + R G+F EPT+FT V D M+IA+EESFGP+MIIS+F D+D V+ RAN TE+GLASGVFT DI+KAL V+D + AGTVF+NTYNKTDVAAPFGGFKQSGFGKDLG+ ALNEYL+ KTVT EY
Sbjct: 43 GLEAEKDGVPVFKFSRWRAKGQALPDVVAKYQALGAELNVLPFCSQFIPMEIINAPQHGSIIYHPSLLPRHRGASAINWTLIHGDKKGGFSIFWADDGLDTGDLLLQKECEVLPDDTVSTLYNRFLFPEGIKGMVQAVRLIAEGKAPRLPQPEEGATYEGIQKKETAKINWDQPAEAIHNWIRGNDKVPGAWTEACEQKLTFFNSTLNTSGLVPEGDALPIPGAHRPGVVTKAGLILFGNDDKMLLVKNIQLED-GKMILASNFFKGAASSAL-ELTEAELVTAEAVRSVWQRILPNVLEVEDSTDFFKSGAASVDVVRLVEEVKELCD-GLELENEDVYMASTFGDFIQLLVRKLRGDDEEGECSIDYVEMAVNKRTIRIPHQLFIGGEFVDAEGAKTYETINPTDGSVICQVSLAQVTDVDKAVAAAKDAFENGRWGKISARDRGRLLYRLADLMEQHQEELATIEALDAGAVYTLALKTHVGMSIQTFRYFAGWCDKIQGSTIPINQARPNRNLTLTRKEPVGVCGIIIPWNYPLMMLSWKTAACLAAGNTVVIKPAQVTPLTALKFAELTLKAGIPKGVVNVLPGSGSLVGQRLSDHPDVRKIGFTGSTEVGKHIMKSCAISNVKKVSLELGGKSPLIIFADCDLNKAVQMGMSSVFFNKGENCIAAGRLFVEDSIHDEFVRRVVEEVRKMKVGDPLDRDTDHGPQNHHAHLMKLMEYCQRGVKEGATLVCGGNQVPRPGFFFEPTVFTDVEDHMFIAKEESFGPVMIISRFADGDVDTVLSRANATEFGLASGVFTRDINKALYVSDKLQAGTVFVNTYNKTDVAAPFGGFKQSGFGKDLGEAALNEYLRVKTVTFEY 902 HSP 2 Score: 70.0922 bits (170), Expect = 9.425e-11 Identity = 30/66 (45.45%), Postives = 48/66 (72.73%), Query Frame = 1
Query: 115 MKIAIIGQSIFGAQVYKELKNEGHDIVGVFTIPDRNGRSDPLGIFYWE*GFTTLLMTSKKSQGRPL 312
MKIA+IGQS+FG +VY L+ EGH++VG FT+PD++G++DPLG+ + G + +++G+ L
Sbjct: 1 MKIAVIGQSLFGQEVYCHLRKEGHEVVGGFTVPDKDGKADPLGLEAEKDGVPVFKFSRWRAKGQAL 66
BLAST of 10-formyltetrahydrofolate dehydrogenase vs. TrEMBL
Match: A0A2C9JVS9 (10-formyltetrahydrofolate dehydrogenase OS=Biomphalaria glabrata OX=6526 GN=106070094 PE=3 SV=1) HSP 1 Score: 1156.35 bits (2990), Expect = 0.000e+0 Identity = 554/860 (64.42%), Postives = 693/860 (80.58%), Query Frame = 3
Query: 438 AMEAIDLGTKVFKIPKWRVNNQIIKEVFEEYRSINAELNVLAFCTQFIPMEVINAPKHRSIIYHPSLLPKHRGASAINWTLINGDLKGGLTIFWADDGLDTGPVLLQRECDVHINDTVDSLYSRFMMPEGIKAMVEAVRQIESGRAPAIAQYHPDHSYDQMVKKSTAEINWNQSGLSLHNFIRGHDKVPGAWSWINGQKVTFYGSQLWYHDVVHDGPSLAIQGLSDPAVLHNHGLLIRGSDNQWINIAQLKFEDTGKTVQASKYGKGDEITTMADLSEDERAMEIPLMKIWKSILMGSDIEPESDFFKLGGTSMDVTRIIEQIKCNFNVELKIDHIYLYSTFDTLFKWIVLRKRGGGSQKKLHYDAVIINANKMTFPIPHQIFINNEFVNSESGKEYDSKNPSDESVICRVSYSSXXXXXXXXXXXXXXFEFGEWGKMSARDRGRILYKLADLMEEHAEELATLESLDSGAVYTLALKTHIGMSIETFRYFAGWCDKIQGSTIPISNARPNKNLSFTKKEPIGVCGIITPWNYPLMMLAWKVAACLAAGNTVVLKPAQVTPLASLKFCELSVEAGFPPGVINVLPGSGAIAGTAISEHPDIRKLGFTGSTAIGQTIMSSCAKSNLKKCSLELGGKSPLIIFSDCDMDKAVKSACSSVFFNKGENCIAAGRIFVDVRIHDVFLKLVVEDVKKMKIGDPLDRSVDHGPQNHEIHLLKLLEFCDIGVKEGAKLVFGGKRCDRKGYFMEPTIFTSVTDDMYIAREESFGPIMIISKFY--DIDEVIVRANKTEYGLASGVFTNDISKALRVADAIDAGTVFINTYNKTDVAAPFGGFKQSGFGKDLGQEALNEYLKTKTVTVEY 3011
A+ A ++G KVFK KW VN ++I EV++EY+++NAELNVL FC+QFIP E+I PK+++IIYHPSLLP+HRGASAINWTL+ GD KGG +IFWADDGLDTGP+LLQR V NDT+++ Y+RF PEGIKAM EAV I + RAP+I Q +++ V+K +IN++Q +HNFIRG+DKVPGAW+ ING+++TF+GS+LW + G + I G A++H G+++ G+D + +N++Q+++ +GK + ASK+GK D T +L+ +E +ME L IWK IL +DI+ DFFK G SMDV R+IE+IK +F+++L I+ +Y+ FD L ++ R RG ++ YDAV I ANKM PHQ+FI+NEFV+S G Y++ NP+DE+VIC+VS ++K+DV+ AV+AAK AFE GEW K++ARDRG +L++LADLME+H EELAT+ESLDSGAVYTLALKTHIGMSI+TFRYFAGWCDKIQG TIPI+NARPNKNL+FTK+EPIGVC I+ PWNYPLMML+WK+AACLAAGNTVVLKPA VTPL +LKF ELSV AGFPPGVIN+LPGSG + G A+SEHPDIRKLGFTGST +G+TIM SCAK+NLKK SLELGGKSPLIIF+DCD+DKAV+ C +VFFNKGENCIAAGR+FV+ IHD F++ V+E++KKMKIG+PLDRS DHGPQNH HL KL+E+CDIGVKEGA LV GGK+CD G F EPT+FT+V D M IA+EESFGP+MIISKF D++ V+ AN TE+GLASGVFT DI KA+RVAD++DAGTVFINTYNKTDVAAPFGGFKQSGFGKDLG+EALNEYLKTKTVT+EY
Sbjct: 43 ALAAANVGVKVFKYSKWMVNKKVIPEVYDEYQALNAELNVLPFCSQFIPNEIILFPKYQTIIYHPSLLPRHRGASAINWTLMCGDKKGGFSIFWADDGLDTGPILLQRSTFVDPNDTLETFYNRFCFPEGIKAMGEAVEMIATNRAPSIVQPEEGATFEPFVRKDKVQINFDQPAADIHNFIRGNDKVPGAWTLINGEQITFFGSRLWSR-LPPRGIQVPIDGAKYSAIVHKDGMILFGNDGKMLNVSQVQYS-SGKMIPASKFGKEDSSTQKLELTPEEVSMENNLKAIWKGIL-NTDIDKTLDFFKAGAGSMDVVRLIEEIKVSFDIKLAIEDVYMNPVFDDLMMCVIRRGRGIEDKEPFTYDAVEIEANKMKLKFPHQVFIDNEFVDSSDGATYNTINPADETVICKVSKATKEDVNRAVEAAKAAFEEGEWSKLNARDRGMLLFRLADLMEQHQEELATIESLDSGAVYTLALKTHIGMSIQTFRYFAGWCDKIQGKTIPINNARPNKNLTFTKREPIGVCAIVVPWNYPLMMLSWKIAACLAAGNTVVLKPAMVTPLTALKFAELSVLAGFPPGVINILPGSGTLVGQAMSEHPDIRKLGFTGSTPVGKTIMESCAKANLKKVSLELGGKSPLIIFNDCDLDKAVRLGCGAVFFNKGENCIAAGRLFVEESIHDEFVQRVIEEIKKMKIGNPLDRSTDHGPQNHRAHLQKLIEYCDIGVKEGATLVRGGKQCDLPGLFFEPTVFTNVEDHMMIAKEESFGPVMIISKFIDGDVNGVLQSANNTEFGLASGVFTQDIDKAMRVADSLDAGTVFINTYNKTDVAAPFGGFKQSGFGKDLGEEALNEYLKTKTVTLEY 899 HSP 2 Score: 67.0106 bits (162), Expect = 2.798e-7 Identity = 27/44 (61.36%), Postives = 37/44 (84.09%), Query Frame = 1
Query: 115 MKIAIIGQSIFGAQVYKELKNEGHDIVGVFTIPDRNGRSDPLGI 246
M+IA+IGQS+FGA+V+K L+ GH+IVGVFT+ D NG+ DPL +
Sbjct: 1 MRIAVIGQSVFGAEVFKLLRKNGHEIVGVFTLQDVNGKQDPLAL 44
BLAST of 10-formyltetrahydrofolate dehydrogenase vs. TrEMBL
Match: A0A2C9JVS6 (10-formyltetrahydrofolate dehydrogenase OS=Biomphalaria glabrata OX=6526 GN=106070094 PE=3 SV=1) HSP 1 Score: 1155.2 bits (2987), Expect = 0.000e+0 Identity = 554/860 (64.42%), Postives = 693/860 (80.58%), Query Frame = 3
Query: 438 AMEAIDLGTKVFKIPKWRVNNQIIKEVFEEYRSINAELNVLAFCTQFIPMEVINAPKHRSIIYHPSLLPKHRGASAINWTLINGDLKGGLTIFWADDGLDTGPVLLQRECDVHINDTVDSLYSRFMMPEGIKAMVEAVRQIESGRAPAIAQYHPDHSYDQMVKKSTAEINWNQSGLSLHNFIRGHDKVPGAWSWINGQKVTFYGSQLWYHDVVHDGPSLAIQGLSDPAVLHNHGLLIRGSDNQWINIAQLKFEDTGKTVQASKYGKGDEITTMADLSEDERAMEIPLMKIWKSILMGSDIEPESDFFKLGGTSMDVTRIIEQIKCNFNVELKIDHIYLYSTFDTLFKWIVLRKRGGGSQKKLHYDAVIINANKMTFPIPHQIFINNEFVNSESGKEYDSKNPSDESVICRVSYSSXXXXXXXXXXXXXXFEFGEWGKMSARDRGRILYKLADLMEEHAEELATLESLDSGAVYTLALKTHIGMSIETFRYFAGWCDKIQGSTIPISNARPNKNLSFTKKEPIGVCGIITPWNYPLMMLAWKVAACLAAGNTVVLKPAQVTPLASLKFCELSVEAGFPPGVINVLPGSGAIAGTAISEHPDIRKLGFTGSTAIGQTIMSSCAKSNLKKCSLELGGKSPLIIFSDCDMDKAVKSACSSVFFNKGENCIAAGRIFVDVRIHDVFLKLVVEDVKKMKIGDPLDRSVDHGPQNHEIHLLKLLEFCDIGVKEGAKLVFGGKRCDRKGYFMEPTIFTSVTDDMYIAREESFGPIMIISKFY--DIDEVIVRANKTEYGLASGVFTNDISKALRVADAIDAGTVFINTYNKTDVAAPFGGFKQSGFGKDLGQEALNEYLKTKTVTVEY 3011
A+ A ++G KVFK KW VN ++I EV++EY+++NAELNVL FC+QFIP E+I PK+++IIYHPSLLP+HRGASAINWTL+ GD KGG +IFWADDGLDTGP+LLQR V NDT+++ Y+RF PEGIKAM EAV I + RAP+I Q +++ V+K +IN++Q +HNFIRG+DKVPGAW+ ING+++TF+GS+LW + G + I G A++H G+++ G+D + +N++Q+++ +GK + ASK+GK D T +L+ +E +ME L IWK IL +DI+ DFFK G SMDV R+IE+IK +F+++L I+ +Y+ FD L ++ R RG ++ YDAV I ANKM PHQ+FI+NEFV+S G Y++ NP+DE+VIC+VS ++K+DV+ AV+AAK AFE GEW K++ARDRG +L++LADLME+H EELAT+ESLDSGAVYTLALKTHIGMSI+TFRYFAGWCDKIQG TIPI+NARPNKNL+FTK+EPIGVC I+ PWNYPLMML+WK+AACLAAGNTVVLKPA VTPL +LKF ELSV AGFPPGVIN+LPGSG + G A+SEHPDIRKLGFTGST +G+TIM SCAK+NLKK SLELGGKSPLIIF+DCD+DKAV+ C +VFFNKGENCIAAGR+FV+ IHD F++ V+E++KKMKIG+PLDRS DHGPQNH HL KL+E+CDIGVKEGA LV GGK+CD G F EPT+FT+V D M IA+EESFGP+MIISKF D++ V+ AN TE+GLASGVFT DI KA+RVAD++DAGTVFINTYNKTDVAAPFGGFKQSGFGKDLG+EALNEYLKTKTVT+EY
Sbjct: 49 ALAAANVGVKVFKYSKWMVNKKVIPEVYDEYQALNAELNVLPFCSQFIPNEIILFPKYQTIIYHPSLLPRHRGASAINWTLMCGDKKGGFSIFWADDGLDTGPILLQRSTFVDPNDTLETFYNRFCFPEGIKAMGEAVEMIATNRAPSIVQPEEGATFEPFVRKDKVQINFDQPAADIHNFIRGNDKVPGAWTLINGEQITFFGSRLWSR-LPPRGIQVPIDGAKYSAIVHKDGMILFGNDGKMLNVSQVQYS-SGKMIPASKFGKEDSSTQKLELTPEEVSMENNLKAIWKGIL-NTDIDKTLDFFKAGAGSMDVVRLIEEIKVSFDIKLAIEDVYMNPVFDDLMMCVIRRGRGIEDKEPFTYDAVEIEANKMKLKFPHQVFIDNEFVDSSDGATYNTINPADETVICKVSKATKEDVNRAVEAAKAAFEEGEWSKLNARDRGMLLFRLADLMEQHQEELATIESLDSGAVYTLALKTHIGMSIQTFRYFAGWCDKIQGKTIPINNARPNKNLTFTKREPIGVCAIVVPWNYPLMMLSWKIAACLAAGNTVVLKPAMVTPLTALKFAELSVLAGFPPGVINILPGSGTLVGQAMSEHPDIRKLGFTGSTPVGKTIMESCAKANLKKVSLELGGKSPLIIFNDCDLDKAVRLGCGAVFFNKGENCIAAGRLFVEESIHDEFVQRVIEEIKKMKIGNPLDRSTDHGPQNHRAHLQKLIEYCDIGVKEGATLVRGGKQCDLPGLFFEPTVFTNVEDHMMIAKEESFGPVMIISKFIDGDVNGVLQSANNTEFGLASGVFTQDIDKAMRVADSLDAGTVFINTYNKTDVAAPFGGFKQSGFGKDLGEEALNEYLKTKTVTLEY 905 HSP 2 Score: 69.707 bits (169), Expect = 4.394e-8 Identity = 28/46 (60.87%), Postives = 38/46 (82.61%), Query Frame = 1
Query: 109 PRMKIAIIGQSIFGAQVYKELKNEGHDIVGVFTIPDRNGRSDPLGI 246
P M+IA+IGQS+FGA+V+K L+ GH+IVGVFT+ D NG+ DPL +
Sbjct: 5 PTMRIAVIGQSVFGAEVFKLLRKNGHEIVGVFTLQDVNGKQDPLAL 50
BLAST of 10-formyltetrahydrofolate dehydrogenase vs. TrEMBL
Match: A0A402ELZ4 (10-formyltetrahydrofolate dehydrogenase OS=Paroedura picta OX=143630 GN=parPi_0004742 PE=3 SV=1) HSP 1 Score: 1141.72 bits (2952), Expect = 0.000e+0 Identity = 557/856 (65.07%), Postives = 684/856 (79.91%), Query Frame = 3
Query: 459 GTKVFKIPKWRVNNQIIKEVFEEYRSINAELNVLAFCTQFIPMEVINAPKHRSIIYHPSLLPKHRGASAINWTLINGDLKGGLTIFWADDGLDTGPVLLQRECDVHINDTVDSLYSRFMMPEGIKAMVEAVRQIESGRAPAIAQYHPDHSYDQMVKKSTAEINWNQSGLSLHNFIRGHDKVPGAWSWINGQKVTFYGSQLWYHDVVHDGPSLAIQGLSDPAVLHNHGLLIRGSDNQWINIAQLKFEDTGKTVQASKYGKGDEITTMADLSEDERAMEIPLMKIWKSILMG-SDIEPESDFFKLGGTSMDVTRIIEQIK--CNFNVELKIDHIYLYSTFDTLFKWIVLRKRGGGSQKKLHYDAVIINANKMTFPIPHQIFINNEFVNSESGKEYDSKNPSDESVICRVSYSSXXXXXXXXXXXXXXFEFGEWGKMSARDRGRILYKLADLMEEHAEELATLESLDSGAVYTLALKTHIGMSIETFRYFAGWCDKIQGSTIPISNARPNKNLSFTKKEPIGVCGIITPWNYPLMMLAWKVAACLAAGNTVVLKPAQVTPLASLKFCELSVEAGFPPGVINVLPGSGAIAGTAISEHPDIRKLGFTGSTAIGQTIMSSCAKSNLKKCSLELGGKSPLIIFSDCDMDKAVKSACSSVFFNKGENCIAAGRIFVDVRIHDVFLKLVVEDVKKMKIGDPLDRSVDHGPQNHEIHLLKLLEFCDIGVKEGAKLVFGGKRCDRKGYFMEPTIFTSVTDDMYIAREESFGPIMIISKFY--DIDEVIVRANKTEYGLASGVFTNDISKALRVADAIDAGTVFINTYNKTDVAAPFGGFKQSGFGKDLGQEALNEYLKTKTVTVEY 3011
GT VFK+PKWRV + I EV E Y+S+ AELNVL FCTQFIPM+VI++PKH SIIYHPS+LP+HRGASAINWTLI GD K G +IFWADDGLDTGP+LLQREC V NDTVD LY+RF+ PEGIKAM EAV+ I G+AP + Q +Y+ + KK AEI+W+Q ++LHN+IRGHDKVPGAWS I+GQKVTFYGS L G LAI+G + P ++ +GL++ G+D + + + L+FED G+ + ASKY DE++T+ DL+E+E+ M + IW+ IL I+ +DFFK G +SMDV R+IE+IK C +EL+ + +Y+ F + +V + RG +++L D V + N MT +P+Q FIN +F+++E GK YDS NP+D SVI +VS+++ DVD AV AAK AFE GEWG+M+AR+RGR++Y+LADLMEEH EELAT+E+LDSGAVYTLALKTH+GMS++TFRYFAGWCDKIQG+TIPI++ARPN NL+FTKKEP+GVC I+ PWNYPLMMLAWK AACLAAGNT+VLKPAQVTPL +LKF ELSV+AGFP GVIN+LPGSG + G +SEHPDIRKLGFTGST IG+ IM SCA SNLKK SLELGGKSPLIIFSDC++DKAV+ +VFFNKGENCIAAGR+FV+ IHD F++ VVE+ KKMKIGDPLDRS DHGPQNH+ HLLKLLE+C++GVKEGA LV GG++ R G+FMEPTI T V D MYIA+EESFGP+M+ISKF D+D V+ RAN+TEYGLASGVFT DI KAL V+D ++AGTVFINTYNKTDVAAPFGGFKQSGFGKDLG+EAL+EYL+TK VTVEY
Sbjct: 73 GTPVFKLPKWRVKGKPIPEVIEAYKSVGAELNVLPFCTQFIPMDVIDSPKHGSIIYHPSILPRHRGASAINWTLIQGDKKAGFSIFWADDGLDTGPILLQRECVVGPNDTVDDLYNRFLFPEGIKAMAEAVQLIADGKAPRVPQSEEGATYEGIQKKENAEISWDQPAVALHNWIRGHDKVPGAWSLIDGQKVTFYGSSL-LDGSAPPGEELAIEGATQPGLVTKNGLVLFGNDRKMLLVRNLQFED-GRMIPASKYFSSDEVSTI-DLTEEEKKMAEEIKSIWEGILSNVPAIDDSTDFFKSGASSMDVVRMIEEIKQKCG-GLELQNEDVYMAPKFGDFIQMVVRKYRGEDKEEELVIDYVSKDVNNMTVKMPYQCFINGQFIDAEDGKTYDSINPTDGSVIAQVSFATVSDVDKAVAAAKNAFEQGEWGRMNARERGRLMYRLADLMEEHQEELATIEALDSGAVYTLALKTHVGMSVQTFRYFAGWCDKIQGTTIPINHARPNHNLTFTKKEPLGVCAIVIPWNYPLMMLAWKSAACLAAGNTLVLKPAQVTPLTALKFAELSVKAGFPKGVINILPGSGGLVGQRLSEHPDIRKLGFTGSTPIGKQIMKSCAVSNLKKVSLELGGKSPLIIFSDCELDKAVRMGMGAVFFNKGENCIAAGRLFVEESIHDEFVRRVVEETKKMKIGDPLDRSTDHGPQNHKAHLLKLLEYCELGVKEGATLVHGGRQVCRPGFFMEPTILTDVEDHMYIAQEESFGPVMVISKFKDGDVDGVLERANRTEYGLASGVFTKDIGKALYVSDKLEAGTVFINTYNKTDVAAPFGGFKQSGFGKDLGEEALHEYLRTKAVTVEY 924 HSP 2 Score: 75.485 bits (184), Expect = 6.519e-10 Identity = 32/83 (38.55%), Postives = 54/83 (65.06%), Query Frame = 1
Query: 70 LKLFQHLHFHNFNPRMKIAIIGQSIFGAQVYKELKNEGHDIVGVFTIPDRNGRSDPLGIFYWE*GFTTLLMTSKKSQGRPLAQ 318
L+ F + + ++K+A+IGQS+FG +VYK L+ EGH +VGVFT+PD+NG++DPL + G + + +G+P+ +
Sbjct: 9 LRQFSNTATAPYQNKLKLALIGQSLFGQEVYKHLQKEGHKVVGVFTVPDKNGKADPLASAAEKDGTPVFKLPKWRVKGKPIPE 91
BLAST of 10-formyltetrahydrofolate dehydrogenase vs. TrEMBL
Match: A0A0B6ZYE6 (10-formyltetrahydrofolate dehydrogenase OS=Arion vulgaris OX=1028688 GN=ORF87344 PE=3 SV=1) HSP 1 Score: 1137.48 bits (2941), Expect = 0.000e+0 Identity = 545/860 (63.37%), Postives = 690/860 (80.23%), Query Frame = 3
Query: 438 AMEAIDLGTKVFKIPKWRVNNQIIKEVFEEYRSINAELNVLAFCTQFIPMEVINAPKHRSIIYHPSLLPKHRGASAINWTLINGDLKGGLTIFWADDGLDTGPVLLQRECDVHINDTVDSLYSRFMMPEGIKAMVEAVRQIESGRAPAIAQYHPDHSYDQMVKKSTAEINWNQSGLSLHNFIRGHDKVPGAWSWINGQKVTFYGSQLWYHDVVHDGPSLAIQGLSDPAVLHNHGLLIRGSDNQWINIAQLKFEDTGKTVQASKYGKGDEITTMADLSEDERAMEIPLMKIWKSILMGSDIEPESDFFKLGGTSMDVTRIIEQIKCNFNVELKIDHIYLYSTFDTLFKWIVLRKRGGGSQKKLHYDAVIINANKMTFPIPHQIFINNEFVNSESGKEYDSKNPSDESVICRVSYSSXXXXXXXXXXXXXXFEFGEWGKMSARDRGRILYKLADLMEEHAEELATLESLDSGAVYTLALKTHIGMSIETFRYFAGWCDKIQGSTIPISNARPNKNLSFTKKEPIGVCGIITPWNYPLMMLAWKVAACLAAGNTVVLKPAQVTPLASLKFCELSVEAGFPPGVINVLPGSGAIAGTAISEHPDIRKLGFTGSTAIGQTIMSSCAKSNLKKCSLELGGKSPLIIFSDCDMDKAVKSACSSVFFNKGENCIAAGRIFVDVRIHDVFLKLVVEDVKKMKIGDPLDRSVDHGPQNHEIHLLKLLEFCDIGVKEGAKLVFGGKRCDRKGYFMEPTIFTSVTDDMYIAREESFGPIMIISKFY--DIDEVIVRANKTEYGLASGVFTNDISKALRVADAIDAGTVFINTYNKTDVAAPFGGFKQSGFGKDLGQEALNEYLKTKTVTVEY 3011
A+ A G KVFK P+W+V Q+I E+ +EY+S+N ELNVL FC+QFIP EVI PK+ +IIYHPS+LP+HRGASAINWTL+ GD KGG TIFWADDGLDTGP+LL + V N+TVDS Y+RF PEGIKAM EAV I +GRAP I Q +YD +++K +INW+Q+ ++HNFIRG+DKVPGAW+ ING+++TF+G++LW + G + I+G S PA++H GL++ G+D + +N++Q+++E +GK + ASK+GK D T +L+ +E + L IWK IL DIE DFFK G SMDV R++E+IK V++ ++ +Y+ + F+ L ++ R RG ++ +D++ I ANKM IP+Q+FI+NEF++S G Y++ NP+DESV+C+VS ++K+DV+ AV+AAKEAFE GEWG+M+ARDRG+++++LADLME+H EELAT+ESLDSGAVYTLALKTH+GMSI+TFRYFAGWCDKI G TIPI+NARP+KNL+FTK+EPIGVC I+ PWNYPLMMLAWK+AACLAAGNTVVLKPA VTPL +LKF ELSV AGFPPGVIN+LPGSGA+ G +SEHPDIRK+GFTGST +G+TIM SCAK+NLKK SLELGGKSPLIIFSDCD+DKAV+ C +VFFNKGENCIAAGR+FV+ IHD FL+ V+ ++ KMKIG+PLDRS DHGPQNH HL L+++C +GVKEGA LV GGK+ +R G F EPT+FT V+D+M+IA+EESFGP+MIISKF DI+ V+ AN TEYGLASGVFT D+ KA+RVAD++ AGTVFINTYNKTDVAAPFGGFKQSGFGKDLG+EALNEYLKTKTVTVEY
Sbjct: 43 AVAAESEGVKVFKYPRWQVKKQVIPEILDEYKSLNPELNVLPFCSQFIPNEVILFPKYETIIYHPSILPRHRGASAINWTLMCGDKKGGFTIFWADDGLDTGPILLIKTTYVDPNETVDSFYNRFCFPEGIKAMGEAVELIATGRAPKIVQPEEGATYDALIRKDKVKINWDQTAQAIHNFIRGNDKVPGAWTKINGEQITFFGARLWTR-LPPRGTEVIIEGKSRPAIVHKGGLVLFGNDGEMVNVSQVQYE-SGKMIPASKFGKTDVSTQRLELTPEEEKITENLKSIWKGIL-NIDIENSLDFFKAGAGSMDVVRLVEEIKEQCEVKIAVEDVYMNTVFEDLVTCVIRRGRGIEDKEPFTFDSIDITANKMKLRIPYQLFIDNEFIDSSDGVTYNTINPADESVVCKVSKATKEDVNRAVEAAKEAFEVGEWGRMNARDRGQLMFRLADLMEQHQEELATIESLDSGAVYTLALKTHVGMSIQTFRYFAGWCDKIHGKTIPINNARPSKNLTFTKREPIGVCAIVVPWNYPLMMLAWKMAACLAAGNTVVLKPAMVTPLTALKFAELSVLAGFPPGVINILPGSGALVGQHLSEHPDIRKIGFTGSTPVGKTIMESCAKANLKKVSLELGGKSPLIIFSDCDLDKAVRLGCGAVFFNKGENCIAAGRLFVEESIHDEFLRRVLAEINKMKIGNPLDRSTDHGPQNHRAHLESLIQYCAVGVKEGATLVKGGKQVNRPGLFFEPTVFTDVSDNMWIAKEESFGPVMIISKFINGDIEGVLRSANDTEYGLASGVFTRDLDKAMRVADSLQAGTVFINTYNKTDVAAPFGGFKQSGFGKDLGEEALNEYLKTKTVTVEY 899 HSP 2 Score: 74.3294 bits (181), Expect = 1.481e-9 Identity = 31/44 (70.45%), Postives = 39/44 (88.64%), Query Frame = 1
Query: 115 MKIAIIGQSIFGAQVYKELKNEGHDIVGVFTIPDRNGRSDPLGI 246
MKIAIIGQS+FGA+V++ L+ GH+IVGVFTIPD NG+SDPL +
Sbjct: 1 MKIAIIGQSVFGAEVFRLLRKNGHEIVGVFTIPDVNGKSDPLAV 44
BLAST of 10-formyltetrahydrofolate dehydrogenase vs. TrEMBL
Match: A0A3P9QAE5 (10-formyltetrahydrofolate dehydrogenase OS=Poecilia reticulata OX=8081 PE=3 SV=1) HSP 1 Score: 1136.71 bits (2939), Expect = 0.000e+0 Identity = 553/855 (64.68%), Postives = 674/855 (78.83%), Query Frame = 3
Query: 459 GTKVFKIPKWRVNNQIIKEVFEEYRSINAELNVLAFCTQFIPMEVINAPKHRSIIYHPSLLPKHRGASAINWTLINGDLKGGLTIFWADDGLDTGPVLLQRECDVHINDTVDSLYSRFMMPEGIKAMVEAVRQIESGRAPAIAQYHPDHSYDQMVKKSTAEINWNQSGLSLHNFIRGHDKVPGAWSWINGQKVTFYGSQLWYHDVVHDGPSLAIQGLSDPAVLHNHGLLIRGSDNQWINIAQLKFEDTGKTVQASKYGKGDEITTMADLSEDERAMEIPLMKIWKSILMG-SDIEPESDFFKLGGTSMDVTRIIEQIKCNFNV-ELKIDHIYLYSTFDTLFKWIVLRKRGGGSQKKLHYDAVIINANKMTFPIPHQIFINNEFVNSESGKEYDSKNPSDESVICRVSYSSXXXXXXXXXXXXXXFEFGEWGKMSARDRGRILYKLADLMEEHAEELATLESLDSGAVYTLALKTHIGMSIETFRYFAGWCDKIQGSTIPISNARPNKNLSFTKKEPIGVCGIITPWNYPLMMLAWKVAACLAAGNTVVLKPAQVTPLASLKFCELSVEAGFPPGVINVLPGSGAIAGTAISEHPDIRKLGFTGSTAIGQTIMSSCAKSNLKKCSLELGGKSPLIIFSDCDMDKAVKSACSSVFFNKGENCIAAGRIFVDVRIHDVFLKLVVEDVKKMKIGDPLDRSVDHGPQNHEIHLLKLLEFCDIGVKEGAKLVFGGKRCDRKGYFMEPTIFTSVTDDMYIAREESFGPIMIISKFY--DIDEVIVRANKTEYGLASGVFTNDISKALRVADAIDAGTVFINTYNKTDVAAPFGGFKQSGFGKDLGQEALNEYLKTKTVTVEY 3011
G VFK P+WRV Q I EV + Y++ AELNVL FC+QFIPMEVI+ PKH SIIYHPSLLP+HRGASAINWTLI+GD KGG T+FWADDGLDTGP+LLQRECDV NDTV+++Y RF+ PEG+K MVEAVR I G+AP I Q +Y+ + KK ++I+WNQS ++HN+IRG+DKVPGAW+ ++GQKVTF+GS L + +G L I G S P ++ GL++ G+D + + + L+FED GK + A++Y +T +L+E+E++ + +WKSIL S IE +DFFK G SMDV R++E++K + +L+ + +Y+ +TF + V + RG +++L D V N N MT IPHQ+FIN EFV++E GK Y + NP+D IC VS + DVD AV AAKEAFE GEWG+M+ RDRGR++YKLADLMEEH +ELAT+E++DSGAVYTLALKTH+GMSI+TFRYFAGWCDKIQGSTIPI+ ARPN+NL+FTKKEPIGVC I+ PWNYPLMMLAWK AACLAAGNTVVLKPAQVTPL +LKF EL+ AG P GV+N+LPGSGA+ G +S+HPD+RKLGFTGST IG+ IM SCA SN+KK SLELGGKSPLIIF DCDMDKAV+ SSVFFNKGENCIAAGR+FV+ IHD FLK VVE+VKKMKIGDPLDRS DHGPQNH+ HL KLLEFC +G+KEGA LV+GGK+ R G+F EPT+FT V D MYIA+EESFGPIMI+SKF ++D+V+ RAN TEYGLASGVFT DISKAL V++ ++AGTVFINTYNKTDVAAPFGGFKQSGFGKDLGQEALNEYLKTK VT+EY
Sbjct: 50 GVPVFKFPRWRVKGQAIPEVVDRYKATGAELNVLPFCSQFIPMEVIDHPKHGSIIYHPSLLPRHRGASAINWTLIHGDKKGGFTVFWADDGLDTGPILLQRECDVEPNDTVNTIYKRFLFPEGVKGMVEAVRLITEGKAPRITQPQEGATYECIQKKDNSKIDWNQSAEAIHNWIRGNDKVPGAWAELDGQKVTFFGSTLVDNGTAANGQPLDIPGASQPGIVTKTGLVLFGNDGKTLLVKNLQFED-GKMIPAAQYFCSGG-STAVELTEEEKSFAEQMRAVWKSILTNVSQIEDSTDFFKSGAASMDVVRLVEEVKLRASACQLQNEDVYMNTTFQDFIQMCVRKLRGEDGEEELVVDYVEKNINNMTVKIPHQLFINGEFVDAEGGKTYKTINPTDGMAICEVSLAQISDVDKAVAAAKEAFESGEWGRMNPRDRGRLIYKLADLMEEHQDELATIEAMDSGAVYTLALKTHVGMSIQTFRYFAGWCDKIQGSTIPINQARPNRNLTFTKKEPIGVCAIVIPWNYPLMMLAWKTAACLAAGNTVVLKPAQVTPLTALKFAELAARAGLPKGVVNILPGSGALVGQRLSDHPDVRKLGFTGSTEIGKHIMKSCAVSNVKKVSLELGGKSPLIIFDDCDMDKAVRLGMSSVFFNKGENCIAAGRLFVEETIHDQFLKKVVEEVKKMKIGDPLDRSTDHGPQNHKAHLDKLLEFCQMGIKEGATLVYGGKQVQRPGFFFEPTVFTDVQDHMYIAKEESFGPIMILSKFKTGEVDDVLRRANATEYGLASGVFTRDISKALYVSERLNAGTVFINTYNKTDVAAPFGGFKQSGFGKDLGQEALNEYLKTKAVTIEY 902 HSP 2 Score: 74.7146 bits (182), Expect = 1.229e-9 Identity = 30/43 (69.77%), Postives = 39/43 (90.70%), Query Frame = 1
Query: 115 MKIAIIGQSIFGAQVYKELKNEGHDIVGVFTIPDRNGRSDPLG 243
MKIA+IGQS+FG +VYKEL+ +GH IVGVFTIPD++G++DPL
Sbjct: 1 MKIAVIGQSLFGQEVYKELRKDGHTIVGVFTIPDKDGKADPLA 43
BLAST of 10-formyltetrahydrofolate dehydrogenase vs. Ensembl Cavefish
Match: aldh1l1 (cytosolic 10-formyltetrahydrofolate dehydrogenase [Source:NCBI gene;Acc:103022276]) HSP 1 Score: 1103.97 bits (2854), Expect = 0.000e+0 Identity = 538/860 (62.56%), Postives = 677/860 (78.72%), Query Frame = 3
Query: 444 EAIDLGTKVFKIPKWRVNNQIIKEVFEEYRSINAELNVLAFCTQFIPMEVINAPKHRSIIYHPSLLPKHRGASAINWTLINGDLKGGLTIFWADDGLDTGPVLLQRECDVHINDTVDSLYSRFMMPEGIKAMVEAVRQIESGRAPAIAQYHPDHSYDQMVKKSTAEINWNQSGLSLHNFIRGHDKVPGAWSWINGQKVTFYGSQLWYHDVVHDGPSLAIQGLSDPAVLHNHGLLIRGSDNQWINIAQLKFEDTGKTVQASKYGKGDEITTMADLSEDERAMEIPLMKIWKSILMGSD-IEPESDFFKLGGTSMDVTRIIEQIKCNFN-VELKIDHIYLYSTFDTLFKWIVLRKRGGGSQKKLHYDAVIINANKMTFPIPHQIFINNEFVNSESGKEYDSKNPSDESVICRVSYSSXXXXXXXXXXXXXXFEFGEWGKMSARDRGRILYKLADLMEEHAEELATLESLDSGAVYTLALKTHIGMSIETFRYFAGWCDKIQGSTIPISNARPNKNLSFTKKEPIGVCGIITPWNYPLMMLAWKVAACLAAGNTVVLKPAQVTPLASLKFCELSVEAGFPPGVINVLPGSGAIAGTAISEHPDIRKLGFTGSTAIGQTIMSSCAKSNLKKCSLELGGKSPLIIFSDCDMDKAVKSACSSVFFNKGENCIAAGRIFVDVRIHDVFLKLVVEDVKKMKIGDPLDRSVDHGPQNHEIHLLKLLEFCDIGVKEGAKLVFGGKRCDRKGYFMEPTIFTSVTDDMYIAREESFGPIMIISKFY--DIDEVIVRANKTEYGLASGVFTNDISKALRVADAIDAGTVFINTYNKTDVAAPFGGFKQSGFGKDLGQEALNEYLKTKTVTVEY 3011
EA G VFK P+WR+ + I EV ++Y+++ AELNVL FC+QFIPMEVI+ PKH SIIYHPSLLP+HRGASAINWTLI+GD KGG T+FWADDGLDTGP+LLQ+EC V +DTV+++Y RF+ PEG+K MVEAV+ I G+AP I Q +Y+ + KK ++I+WNQ ++HN+IRG+DKVPGAW+ ++G+ VTFYGS L + +G L I G S P ++ +GL++ G+D + + + L+FED GK + A++Y K ++ +L+E+E++ + +W SIL + I+ +DFFK G SMDV R++E++K + ++L+ + +Y+ +TF + V + RG ++++L D V +N N MT +PHQ+FIN EFV++E GK Y + NP+ IC VS + DV+ AV AAKEAFE GEWGKM+ RDRGR++YKLADLME+H EELAT+ES+DSGAVYTLALKTH+GMSI+TFRYFAGWCDKIQG TIPI+ ARPN+NL+FTKKEPIGVC I+ PWNYPLMMLAWK AACLAAGNTVVLKPAQVTPL ++KF EL+ AGFP GVIN+LPGSG++ G +S+HPD+RKLGFTGST IG+ IM SCA SN+KK SLELGGKSPLIIFSDCD+DKAV+ SSVFFNKGENCIAAGR+FV+ +HD F++ V+E+VKKMKIGDPLDRS DHGPQNH+ HL KL+E+C+ GVKEGA L+ GGK+ +R G+F EPT+FT V D MYIA EESFGP+MIISKF D+D V+ RAN TEYGLASGVFT DISKAL V++ + AGTVF+NTYNKTDVAAPFGGFKQSGFGKDLGQEALNEYLKTKTVTVEY
Sbjct: 45 EAEKDGVPVFKFPRWRLKGKAIDEVVDKYKAVGAELNVLPFCSQFIPMEVIDHPKHGSIIYHPSLLPRHRGASAINWTLIHGDKKGGFTVFWADDGLDTGPILLQKECVVEPDDTVNTIYKRFLFPEGVKGMVEAVKLIAEGKAPKIKQPEEGATYECIQKKDNSKIDWNQPAEAIHNWIRGNDKVPGAWAEVDGKNVTFYGSTLVDNGSTANGQPLEIPGASRPGLVTKNGLVLFGNDGKTLLVKNLQFED-GKMIAAAQYFKAGS-SSAVELTEEEKSFAEQMRAVWTSILTNVEKIDDSTDFFKSGAASMDVVRLVEEVKLRASQLQLQNEDVYMATTFQEFIQMCVRKLRGEDAEEELVVDYVEMNVNNMTIRMPHQLFINGEFVDAEGGKNYKTINPTTGQAICEVSLAQISDVEKAVAAAKEAFEEGEWGKMNHRDRGRLIYKLADLMEQHQEELATIESIDSGAVYTLALKTHVGMSIQTFRYFAGWCDKIQGCTIPINQARPNRNLTFTKKEPIGVCAIVIPWNYPLMMLAWKTAACLAAGNTVVLKPAQVTPLTAVKFAELAARAGFPKGVINILPGSGSLVGQRLSDHPDVRKLGFTGSTEIGKQIMKSCAVSNVKKVSLELGGKSPLIIFSDCDLDKAVRMGMSSVFFNKGENCIAAGRLFVEESLHDTFVQRVIEEVKKMKIGDPLDRSTDHGPQNHKAHLDKLVEYCERGVKEGATLICGGKQVNRPGFFFEPTVFTDVQDHMYIAIEESFGPVMIISKFKNGDVDGVLQRANATEYGLASGVFTRDISKALYVSERLQAGTVFVNTYNKTDVAAPFGGFKQSGFGKDLGQEALNEYLKTKTVTVEY 902 HSP 2 Score: 77.411 bits (189), Expect = 6.350e-14 Identity = 32/43 (74.42%), Postives = 40/43 (93.02%), Query Frame = 1
Query: 115 MKIAIIGQSIFGAQVYKELKNEGHDIVGVFTIPDRNGRSDPLG 243
M+IA+IGQS+FG +VYKELK EGH IVGVFTIPD++G++DPLG
Sbjct: 1 MRIAVIGQSLFGQEVYKELKKEGHIIVGVFTIPDKDGKADPLG 43
BLAST of 10-formyltetrahydrofolate dehydrogenase vs. Ensembl Cavefish
Match: aldh1l1 (cytosolic 10-formyltetrahydrofolate dehydrogenase [Source:NCBI gene;Acc:103022276]) HSP 1 Score: 1102.43 bits (2850), Expect = 0.000e+0 Identity = 538/860 (62.56%), Postives = 677/860 (78.72%), Query Frame = 3
Query: 444 EAIDLGTKVFKIPKWRVNNQIIKEVFEEYRSINAELNVLAFCTQFIPMEVINAPKHRSIIYHPSLLPKHRGASAINWTLINGDLKGGLTIFWADDGLDTGPVLLQRECDVHINDTVDSLYSRFMMPEGIKAMVEAVRQIESGRAPAIAQYHPDHSYDQMVKKSTAEINWNQSGLSLHNFIRGHDKVPGAWSWINGQKVTFYGSQLWYHDVVHDGPSLAIQGLSDPAVLHNHGLLIRGSDNQWINIAQLKFEDTGKTVQASKYGKGDEITTMADLSEDERAMEIPLMKIWKSILMGSD-IEPESDFFKLGGTSMDVTRIIEQIKCNFN-VELKIDHIYLYSTFDTLFKWIVLRKRGGGSQKKLHYDAVIINANKMTFPIPHQIFINNEFVNSESGKEYDSKNPSDESVICRVSYSSXXXXXXXXXXXXXXFEFGEWGKMSARDRGRILYKLADLMEEHAEELATLESLDSGAVYTLALKTHIGMSIETFRYFAGWCDKIQGSTIPISNARPNKNLSFTKKEPIGVCGIITPWNYPLMMLAWKVAACLAAGNTVVLKPAQVTPLASLKFCELSVEAGFPPGVINVLPGSGAIAGTAISEHPDIRKLGFTGSTAIGQTIMSSCAKSNLKKCSLELGGKSPLIIFSDCDMDKAVKSACSSVFFNKGENCIAAGRIFVDVRIHDVFLKLVVEDVKKMKIGDPLDRSVDHGPQNHEIHLLKLLEFCDIGVKEGAKLVFGGKRCDRKGYFMEPTIFTSVTDDMYIAREESFGPIMIISKFY--DIDEVIVRANKTEYGLASGVFTNDISKALRVADAIDAGTVFINTYNKTDVAAPFGGFKQSGFGKDLGQEALNEYLKTKTVTVEY 3011
EA G VFK P+WR+ + I EV ++Y+++ AELNVL FC+QFIPMEVI+ PKH SIIYHPSLLP+HRGASAINWTLI+GD KGG T+FWADDGLDTGP+LLQ+EC V +DTV+++Y RF+ PEG+K MVEAV+ I G+AP I Q +Y+ + KK ++I+WNQ ++HN+IRG+DKVPGAW+ ++G+ VTFYGS L + +G L I G S P ++ +GL++ G+D + + + L+FED GK + A++Y K ++ +L+E+E++ + +W SIL + I+ +DFFK G SMDV R++E++K + ++L+ + +Y+ +TF + V + RG ++++L D V +N N MT +PHQ+FIN EFV++E GK Y + NP+ IC VS + DV+ AV AAKEAFE GEWGKM+ RDRGR++YKLADLME+H EELAT+ES+DSGAVYTLALKTH+GMSI+TFRYFAGWCDKIQG TIPI+ ARPN+NL+FTKKEPIGVC I+ PWNYPLMMLAWK AACLAAGNTVVLKPAQVTPL ++KF EL+ AGFP GVIN+LPGSG++ G +S+HPD+RKLGFTGST IG+ IM SCA SN+KK SLELGGKSPLIIFSDCD+DKAV+ SSVFFNKGENCIAAGR+FV+ +HD F++ V+E+VKKMKIGDPLDRS DHGPQNH+ HL KL+E+C+ GVKEGA L+ GGK+ +R G+F EPT+FT V D MYIA EESFGP+MIISKF D+D V+ RAN TEYGLASGVFT DISKAL V++ + AGTVF+NTYNKTDVAAPFGGFKQSGFGKDLGQEALNEYLKTKTVTVEY
Sbjct: 13 EAEKDGVPVFKFPRWRLKGKAIDEVVDKYKAVGAELNVLPFCSQFIPMEVIDHPKHGSIIYHPSLLPRHRGASAINWTLIHGDKKGGFTVFWADDGLDTGPILLQKECVVEPDDTVNTIYKRFLFPEGVKGMVEAVKLIAEGKAPKIKQPEEGATYECIQKKDNSKIDWNQPAEAIHNWIRGNDKVPGAWAEVDGKNVTFYGSTLVDNGSTANGQPLEIPGASRPGLVTKNGLVLFGNDGKTLLVKNLQFED-GKMIAAAQYFKAGS-SSAVELTEEEKSFAEQMRAVWTSILTNVEKIDDSTDFFKSGAASMDVVRLVEEVKLRASQLQLQNEDVYMATTFQEFIQMCVRKLRGEDAEEELVVDYVEMNVNNMTIRMPHQLFINGEFVDAEGGKNYKTINPTTGQAICEVSLAQISDVEKAVAAAKEAFEEGEWGKMNHRDRGRLIYKLADLMEQHQEELATIESIDSGAVYTLALKTHVGMSIQTFRYFAGWCDKIQGCTIPINQARPNRNLTFTKKEPIGVCAIVIPWNYPLMMLAWKTAACLAAGNTVVLKPAQVTPLTAVKFAELAARAGFPKGVINILPGSGSLVGQRLSDHPDVRKLGFTGSTEIGKQIMKSCAVSNVKKVSLELGGKSPLIIFSDCDLDKAVRMGMSSVFFNKGENCIAAGRLFVEESLHDTFVQRVIEEVKKMKIGDPLDRSTDHGPQNHKAHLDKLVEYCERGVKEGATLICGGKQVNRPGFFFEPTVFTDVQDHMYIAIEESFGPVMIISKFKNGDVDGVLQRANATEYGLASGVFTRDISKALYVSERLQAGTVFVNTYNKTDVAAPFGGFKQSGFGKDLGQEALNEYLKTKTVTVEY 870
BLAST of 10-formyltetrahydrofolate dehydrogenase vs. Ensembl Cavefish
Match: aldh1l2 (aldehyde dehydrogenase 1 family, member L2 [Source:ZFIN;Acc:ZDB-GENE-100426-6]) HSP 1 Score: 1095.11 bits (2831), Expect = 0.000e+0 Identity = 543/864 (62.85%), Postives = 675/864 (78.12%), Query Frame = 3
Query: 438 AMEAIDLGTKVFKIPKWRVNNQIIKEVFEEYRSINAELNVLAFCTQFIPMEVINAPKHRSIIYHPSLLPKHRGASAINWTLINGDLKGGLTIFWADDGLDTGPVLLQRECDVHINDTVDSLYSRFMMPEGIKAMVEAVRQIESGRAPAIAQYHPDHSYDQMVKKSTAEINWNQSGLSLHNFIRGHDKVPGAWSWINGQKVTFYGSQLWYHDVVHDGPSLAIQGLSDPAVLHNHGLLIRGSDNQWINIAQLKFEDTGKTVQASKY-GKGDEITTMADLSEDERAMEIPLMKIWKSILMG-SDIEPESDFFKLGGTSMDVTRIIEQIK--CNFNVELKIDHIYLYSTFDTLFKWIVLRKRGGGSQKKLHYDAVIINANKMTFPIPHQIFINNEFVNSESGKEYDSKNPSDESVICRVSYSSXXXXXXXXXXXXXXFEFGEWGKMSARDRGRILYKLADLMEEHAEELATLESLDSGAVYTLALKTHIGMSIETFRYFAGWCDKIQGSTIPISNARPNKNLSFTKKEPIGVCGIITPWNYPLMMLAWKVAACLAAGNTVVLKPAQVTPLASLKFCELSVEAGFPPGVINVLPGSGAIAGTAISEHPDIRKLGFTGSTAIGQTIMSSCAKSNLKKCSLELGGKSPLIIFSDCDMDKAVKSACSSVFFNKGENCIAAGRIFVDVRIHDVFLKLVVEDVKKMKIGDPLDRSVDHGPQNHEIHLLKLLEFCDIGVKEGAKLVFGGKRCDRKGYFMEPTIFTSVTDDMYIAREESFGPIMIISKFY--DIDEVIVRANKTEYGLASGVFTNDISKALRVADAIDAGTVFINTYNKTDVAAPFGGFKQSGFGKDLGQEALNEYLKTKTVTVEY 3011
A+ A GT VFK P+WRV + I EV E Y+++ AELNV+ FC+QFIPM VI+ PKH SIIYHPSLLPKHRGASAINWTLI GD K G +IFWADDGLDTGPVLLQ+ECDV NDTVD+LY+RF+ PEGIK+MVEAV+ I G+AP I Q SY+ + KKS A++N Q ++HN+IRGHDKVPGAW+ I+GQ VT YGS L D V G +L ++G S P ++ + GL++ GSD + + + L+FED GK + ASKY GD TT +L+E+E+ M + IWK IL + IE +DFFK G SMDV R++E+IK C +V+L+ + +Y+ ++F + V R RG +++L + V N N MT +P+Q FIN F ++E+GK Y++ NP+D SVIC+VS++S DVD AV AAKEAFE G WGKM+ RDRGR+LY+LADLMEEH EELAT+ES+DSGAVYTLALKTH+GMSI+TFRYFAGWCDKIQG+TIPI+ ARPN+NL+FTKKEP+GVC I+ PWNYPLMMLAWK AACLAAGNT++LKPAQVTPL +LKF EL+V+AG P GVIN++PGSG + G +S+HPDIRKLGFTGST IG+ IM SCA SNLKK SL+ DCDMDKAV+ SSV+FNKGENCIAAGR+FV+ IHD F+ VVE++KKMKIGDPLDRS DHGPQNH+ HL KL+E+C+IGVKEGA L++GG++ DR GYFMEPT+FT V D M+IA+EESFGP+M++SKF D+D V+ RAN TE+GLASGVFT DI+KA+ +++ ++AGTVFINTYNKTDVAAPFGGFKQSGFGKDLG+EAL+EYL+TK VTVEY
Sbjct: 43 AVAAEKDGTPVFKFPRWRVKGKPIPEVVEAYKAVGAELNVMPFCSQFIPMNVIDNPKHGSIIYHPSLLPKHRGASAINWTLIEGDKKAGFSIFWADDGLDTGPVLLQKECDVEPNDTVDTLYNRFLFPEGIKSMVEAVQLIADGKAPRIPQPEEGASYEGIQKKSNAKVNMAQPAEAIHNWIRGHDKVPGAWAVIDGQPVTLYGSSL-LSDPVPAGQTLNVEGASQPGLITSSGLVLFGSDGKALQVKNLQFED-GKMIPASKYFSSGD--TTSVELTEEEKKMAEEIRMIWKGILSNVAVIEDTTDFFKSGAASMDVVRLVEEIKQKCG-SVQLENEDVYMATSFQEFIQMFVRRLRGEDQEEELVINYVS-NINGMTLKMPYQCFINGVFEDAENGKTYETVNPTDGSVICKVSFASVGDVDRAVVAAKEAFENGPWGKMNPRDRGRLLYRLADLMEEHQEELATIESIDSGAVYTLALKTHVGMSIQTFRYFAGWCDKIQGTTIPINQARPNRNLTFTKKEPLGVCAIVIPWNYPLMMLAWKSAACLAAGNTLILKPAQVTPLTALKFAELTVKAGIPKGVINIVPGSGGMVGQRMSDHPDIRKLGFTGSTPIGKQIMKSCAASNLKKVSLD-----------DCDMDKAVRMGMSSVYFNKGENCIAAGRLFVEESIHDEFITRVVEEIKKMKIGDPLDRSTDHGPQNHKAHLDKLVEYCEIGVKEGATLIYGGRQVDRPGYFMEPTVFTDVEDHMFIAKEESFGPVMVVSKFKQGDVDGVLRRANDTEFGLASGVFTRDINKAMYISERLEAGTVFINTYNKTDVAAPFGGFKQSGFGKDLGEEALHEYLRTKAVTVEY 889 HSP 2 Score: 67.3958 bits (163), Expect = 7.128e-11 Identity = 27/68 (39.71%), Postives = 47/68 (69.12%), Query Frame = 1
Query: 115 MKIAIIGQSIFGAQVYKELKNEGHDIVGVFTIPDRNGRSDPLGIFYWE*GFTTLLMTSKKSQGRPLAQ 318
+K+A+IGQS+FG +VY L+ +GH +VGVFT+PD++G++DPL + + G + +G+P+ +
Sbjct: 1 LKLALIGQSLFGQEVYTNLRKQGHKVVGVFTVPDKDGKADPLAVAAEKDGTPVFKFPRWRVKGKPIPE 68
BLAST of 10-formyltetrahydrofolate dehydrogenase vs. Ensembl Cavefish
Match: aldh1l1 (cytosolic 10-formyltetrahydrofolate dehydrogenase [Source:NCBI gene;Acc:103022276]) HSP 1 Score: 1069.3 bits (2764), Expect = 0.000e+0 Identity = 521/844 (61.73%), Postives = 661/844 (78.32%), Query Frame = 3
Query: 444 EAIDLGTKVFKIPKWRVNNQIIKEVFEEYRSINAELNVLAFCTQFIPMEVINAPKHRSIIYHPSLLPKHRGASAINWTLINGDLKGGLTIFWADDGLDTGPVLLQRECDVHINDTVDSLYSRFMMPEGIKAMVEAVRQIESGRAPAIAQYHPDHSYDQMVKKSTAEINWNQSGLSLHNFIRGHDKVPGAWSWINGQKVTFYGSQLWYHDVVHDGPSLAIQGLSDPAVLHNHGLLIRGSDNQWINIAQLKFEDTGKTVQASKYGKGDEITTMADLSEDERAMEIPLMKIWKSILMGSD-IEPESDFFKLGGTSMDVTRIIEQIKCNFN-VELKIDHIYLYSTFDTLFKWIVLRKRGGGSQKKLHYDAVIINANKMTFPIPHQIFINNEFVNSESGKEYDSKNPSDESVICRVSYSSXXXXXXXXXXXXXXFEFGEWGKMSARDRGRILYKLADLMEEHAEELATLESLDSGAVYTLALKTHIGMSIETFRYFAGWCDKIQGSTIPISNARPNKNLSFTKKEPIGVCGIITPWNYPLMMLAWKVAACLAAGNTVVLKPAQVTPLASLKFCELSVEAGFPPGVINVLPGSGAIAGTAISEHPDIRKLGFTGSTAIGQTIMSSCAKSNLKKCSLELGGKSPLIIFSDCDMDKAVKSACSSVFFNKGENCIAAGRIFVDVRIHDVFLKLVVEDVKKMKIGDPLDRSVDHGPQNHEIHLLKLLEFCDIGVKEGAKLVFGGKRCDRKGYFMEPTIFTSVTDDMYIAREESFGPIMIISKFY--DIDEVIVRANKTEYGLASGVFTNDISKALRVADAIDAGTVFINTYNKTDVAAPFGGFKQSGFGKDLGQ 2963
EA G VFK P+WR+ + I EV ++Y+++ AELNVL FC+QFIPMEVI+ PKH SIIYHPSLLP+HRGASAINWTLI+GD KGG T+FWADDGLDTGP+LLQ+EC V +DTV+++Y RF+ PEG+K MVEAV+ I G+AP I Q +Y+ + KK ++I+WNQ ++HN+IRG+DKVPGAW+ ++G+ VTFYGS L + +G L I G S P ++ +GL++ G+D + + + L+FED GK + A++Y K ++ +L+E+E++ + +W SIL + I+ +DFFK G SMDV R++E++K + ++L+ + +Y+ +TF + V + RG ++++L D V +N N MT +PHQ+FIN EFV++E GK Y + NP+ IC VS + DV+ AV AAKEAFE GEWGKM+ RDRGR++YKLADLME+H EELAT+ES+DSGAVYTLALKTH+GMSI+TFRYFAGWCDKIQG TIPI+ ARPN+NL+FTKKEPIGVC I+ PWNYPLMMLAWK AACLAAGNTVVLKPAQVTPL ++KF EL+ AGFP GVIN+LPGSG++ G +S+HPD+RKLGFTGST IG+ IM SCA SN+KK SLELGGKSPLIIFSDCD+DKAV+ SSVFFNKGENCIAAGR+FV+ +HD F++ V+E+VKKMKIGDPLDRS DHGPQNH+ HL KL+E+C+ GVKEGA L+ GGK+ +R G+F EPT+FT V D MYIA EESFGP+MIISKF D+D V+ RAN TEYGLASGVFT DISKAL V++ + AGTVF+NTYNKTDVAAPFGGFKQSGFGKDLG+
Sbjct: 8 EAEKDGVPVFKFPRWRLKGKAIDEVVDKYKAVGAELNVLPFCSQFIPMEVIDHPKHGSIIYHPSLLPRHRGASAINWTLIHGDKKGGFTVFWADDGLDTGPILLQKECVVEPDDTVNTIYKRFLFPEGVKGMVEAVKLIAEGKAPKIKQPEEGATYECIQKKDNSKIDWNQPAEAIHNWIRGNDKVPGAWAEVDGKNVTFYGSTLVDNGSTANGQPLEIPGASRPGLVTKNGLVLFGNDGKTLLVKNLQFED-GKMIAAAQYFKAGS-SSAVELTEEEKSFAEQMRAVWTSILTNVEKIDDSTDFFKSGAASMDVVRLVEEVKLRASQLQLQNEDVYMATTFQEFIQMCVRKLRGEDAEEELVVDYVEMNVNNMTIRMPHQLFINGEFVDAEGGKNYKTINPTTGQAICEVSLAQISDVEKAVAAAKEAFEEGEWGKMNHRDRGRLIYKLADLMEQHQEELATIESIDSGAVYTLALKTHVGMSIQTFRYFAGWCDKIQGCTIPINQARPNRNLTFTKKEPIGVCAIVIPWNYPLMMLAWKTAACLAAGNTVVLKPAQVTPLTAVKFAELAARAGFPKGVINILPGSGSLVGQRLSDHPDVRKLGFTGSTEIGKQIMKSCAVSNVKKVSLELGGKSPLIIFSDCDLDKAVRMGMSSVFFNKGENCIAAGRLFVEESLHDTFVQRVIEEVKKMKIGDPLDRSTDHGPQNHKAHLDKLVEYCERGVKEGATLICGGKQVNRPGFFFEPTVFTDVQDHMYIAIEESFGPVMIISKFKNGDVDGVLQRANATEYGLASGVFTRDISKALYVSERLQAGTVFVNTYNKTDVAAPFGGFKQSGFGKDLGK 849
BLAST of 10-formyltetrahydrofolate dehydrogenase vs. Ensembl Cavefish
Match: aldh1a2 (aldehyde dehydrogenase 1 family member A2 [Source:NCBI gene;Acc:103042804]) HSP 1 Score: 468.774 bits (1205), Expect = 1.833e-153 Identity = 248/484 (51.24%), Postives = 322/484 (66.53%), Query Frame = 3
Query: 1578 QIFINNEFVNSESGKEYDSKNPSDESVICRVSYSSXXXXXXXXXXXXXXFEFG-EWGKMSARDRGRILYKLADLMEEHAEELATLESLDSGAVYTLALKTHIGMSIETFRYFAGWCDKIQGSTIPISNARPNKNLSFTKKEPIGVCGIITPWNYPLMMLAWKVAACLAAGNTVVLKPAQVTPLASLKFCELSVEAGFPPGVINVLPGSGAIAGTAISEHPDIRKLGFTGSTAIGQTIMSSCAKSNLKKCSLELGGKSPLIIFSDCDMDKAVKSACSSVFFNKGENCIAAGRIFVDVRIHDVFLKLVVEDVKKMKIGDPLDRSVDHGPQNHEIHLLKLLEFCDIGVKEGAKLVFGGKRCDRKGYFMEPTIFTSVTDDMYIAREESFGPIMIISKFYDIDEVIVRANKTEYGLASGVFTNDISKALRVADAIDAGTVFINTYNKTDVAAPFGGFKQSGFGKDLGQEALNEYLKTKTVTVEY*NGSC 3026
+IFINNE+ +S SGK + + NP+ IC V + K DVD AVKAA+ AF EW +M + DRGR+L KLADL+E LATLESLD+G + + + +I+T RYFAGW DKI G++IP LSFT+ EPIGVCG I PWN+PLMM+AWK+ L GNTVV+KPA+ TPL L L EAGFPPGV+N+LPG G AG I+ H I K+ FTGST +G+ I + KSNLK+ +LELGGK+P IIF+D D+D AV+ A VFFN G+ C A RIFV+ I+D F+ VE K+ +G P D + + GPQ ++LEF + G+ EGAKL GGK KG++++PT+F++V D M IAREE FGP+ I KF ++EVI RAN TEYGL + VFTNDISKA+ ++ A+ AGTV+IN +N PFGGFK SG G++LG+ L EY + KT+TV+ SC
Sbjct: 40 KIFINNEWHDSLSGKTFSTYNPATGEKICDVQEADKADVDKAVKAARSAFSLSSEWRRMDSSDRGRLLSKLADLVERDRLYLATLESLDTGKPFLSSFFVDLQGTIKTLRYFAGWADKIHGTSIPTDGGY----LSFTRHEPIGVCGQIIPWNFPLMMMAWKLGPALCCGNTVVMKPAEQTPLTCLYMGSLIKEAGFPPGVVNILPGFGPTAGAGIASHMGIDKVAFTGSTKVGKLIQEAAGKSNLKRVTLELGGKNPNIIFADADLDLAVEQAHQGVFFNSGQCCTAGSRIFVEESIYDEFVSRSVERAKRRIVGSPFDPTTEQGPQISAEQQRRVLEFVESGISEGAKLECGGKAHFSKGFYIQPTVFSNVQDHMRIAREEIFGPVQQIMKFKTMEEVIERANNTEYGLTAAVFTNDISKAMAISTALQAGTVWINCFNALSCQCPFGGFKMSGNGRELGEYGLREYTEVKTITVKMPVISC 519
BLAST of 10-formyltetrahydrofolate dehydrogenase vs. Ensembl Sea Lamprey
Match: aldh1l2 (aldehyde dehydrogenase 1 family, member L2 [Source:ZFIN;Acc:ZDB-GENE-100426-6]) HSP 1 Score: 875.544 bits (2261), Expect = 0.000e+0 Identity = 434/697 (62.27%), Postives = 543/697 (77.91%), Query Frame = 3
Query: 936 AEINWNQSGLSLHNFIRGHDKVPGAWSWINGQKVTFYGSQLWYHDVVHDGPSLAIQGLSDPAVLHNHGLLIRGSDNQWINIAQLKFEDTGKTVQASKYGKGDEITTMADLSEDERAMEIPLMKIWKSILMGSDI-EPESDFFKLGGTSMDVTRIIEQIKCNF-NVELKIDHIYLYSTFDTLFKWIVLRKRGGGSQKKLHYDAVIINANKMTFPIPHQIFINNEFVNSESGKEYDSKNPSDESVICRVSYSSXXXXXXXXXXXXXXFEFGEWGKMSARDRGRILYKLADLMEEHAEELATLESLDSGAVYTLALKTHIGMSIETFRYFAGWCDKIQGSTIPISNARPNKNLSFTKKEPIGVCGIITPWNYPLMMLAWKVAACLAAGNTVVLKPAQVTPLASLKFCELSVEAGFPPGVINVLPGS-GAIAGTAISEHPDIRKLGFTGSTAIGQTIMSSCAKSNLKKCSLELGGKSPLIIFSDCDMDKAVKSACSSVFFNKGENCIAAGRIFVDVRIHDVFLKLVVEDVKKMKIGDPLDRSVDHGPQNHEIHLLKLLEFCDIGVKEGAKLVFGGKRCDRKGYFMEPTIFTSVTDDMYIAREESFGPIMIISKFY--DIDEVIVRANKTEYGLASGVFTNDISKALRVADAIDAGTVFINTYNKTDVAAPFGGFKQSGFGKDLGQEALNEYLKTKTVTVEY 3011
A+IN++Q ++HN+IRGHDKVPGAW+ I+GQ++T +GS L V P L I G + P + GLL+ G+D + + + L+FED V A + GDE + +L++DE+A + IW SIL + E +DFFK G SMDV R+IE++K +++L+ + +Y+ ++F +V R RG ++L D V+ N +T IPHQ FI+ +FV++++ K YD+ NP+D SVIC+V+++S DVD AV AAK AFE GEWG+M+ RDRGR+LYKLADLMEEH EELAT+E+LDSGAVYTLALKTH+GMSI+TFRYFAGWCDKI G+TIPI+ ARPN+NL+FTK+EPIGVCGI+ PWNYPLMMLAWK AACLAAGNT+VLKPAQVTPL +LKF EL+ +AGFP GVIN++PGS G+I G +SEHP IRKLGFTGST IG+ IM SCA SNLKK SLELGGKSPLIIF+DCD+DKAV+ S+VFFNKGENCIAAGR+FV+ IHD +++ VVE++KKMK+GDPLDRS DHGPQNH H+ KL+E+C++GVKEGA LV GG++ R F P++FT V D MYIA+EESFGPIM+ISKF DID V+ RAN TE+GLASGVFT DISKAL V+D ++AGTVFINTYNKTDVAAPFGGFKQSGFGKDLG+EALNEYL+TK VTVEY
Sbjct: 1 AQINFDQPAEAIHNWIRGHDKVPGAWTLIDGQRLTLFGSSLANVGTVVGQP-LEIPGATQPGTITKSGLLLHGNDGKTLLVRNLQFEDG---VPAKYFSSGDEGSV--ELTDDEKAFAEEVRAIWMSILSNVPVVEDSTDFFKSGAASMDVVRLIEELKQRRGDLQLQTEDVYMATSFRDFTHMVVRRLRGEDRAEELAVDHVVKEVNNLTVRIPHQCFIDGKFVDADTSKTYDTVNPTDGSVICKVAFASVADVDEAVAAAKRAFESGEWGRMNPRDRGRLLYKLADLMEEHQEELATIETLDSGAVYTLALKTHVGMSIQTFRYFAGWCDKIHGTTIPINQARPNRNLTFTKREPIGVCGIVIPWNYPLMMLAWKSAACLAAGNTLVLKPAQVTPLTALKFAELAAKAGFPKGVINIIPGSVGSIVGQRMSEHPHIRKLGFTGSTPIGKQIMKSCATSNLKKVSLELGGKSPLIIFNDCDIDKAVRMGMSAVFFNKGENCIAAGRLFVEESIHDEYVRRVVEEIKKMKVGDPLDRSTDHGPQNHRAHMEKLVEYCEVGVKEGATLVHGGRQVPRPEVFANPSVFTGVEDHMYIAQEESFGPIMVISKFPDGDIDGVLARANNTEFGLASGVFTRDISKALYVSDQLEAGTVFINTYNKTDVAAPFGGFKQSGFGKDLGEEALNEYLRTKAVTVEY 691
BLAST of 10-formyltetrahydrofolate dehydrogenase vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004609.1 (pep scaffold:Pmarinus_7.0:GL479321:13801:23388:1 gene:ENSPMAG00000004155.1 transcript:ENSPMAT00000004609.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 338.191 bits (866), Expect = 1.481e-104 Identity = 191/482 (39.63%), Postives = 279/482 (57.88%), Query Frame = 3
Query: 1608 SESGKEYDSKNPSDESVICRVSYSSXXXXXXXXXXXXXXFEFGEWGKMSARDRGRILYKLADLMEEHAEELATLESLDSG-AVYTLALKTHIGMSIETFRYFAGWCDKIQGSTIPISNARPNKNLSFTKKEPIGVCGIITPWNYPLMMLAWKVAACLAAGNTVVLKPAQVTPLASLKFCELSVEAGFPPGVINVLPGSGAIAGTAISEHPDIRKLGFTGSTAIGQTIMSSCAKSNLKKCSLELGGKSPLIIFSDCDMDKAVKSACSSVFFNKGENCIAAGRIFVDVRIHDVFLKLVVEDVKKMKIGDPLDRSVDHGPQNHEIHLLKLLEFCDIGVKEGAKLVFGGKR------CDRKGYFMEPTIFTSVTDDMYIAREESFGPIMIISKFYDIDEVIVRANKTEYGLASGVFTNDISKALRVADAIDAGTVFINTYNKTDVAAPFGGFKQSGFGKDLGQEALNEYLKTKTVTVEY*NGSCGL 3032
S G E+D NP+ ++CR S DV AVK A+EAFE G W +S +R + L + + +++E EELA +E D+G VY + G + YFAG I G I + P + ++++EP+GVC I WN+P + WK A LA GN +V KP+ +TPL ++ E+ EAG PPG+ N++ G G G + H D+ K+ TGS G ++ A +K +LELGGKSPLI+FSDCD+D AVK+A F ++G+ C A R+FV + + FL+ +++ V ++IGDP S G + HL ++L + V+EGAKLV GGK+ + G+FM P + DDM REE FGP+M + F +EV+ RAN T++GLA+GVFT D+++A RV A+ AG+ +IN YN + PFGG+K SGFG++ G ++ Y + KTV VE + +C L
Sbjct: 53 STGGPEFDVVNPATGGLLCRGQASGAVDVQAAVKDAREAFE-GSWRGLSGSERSQHLLRASAIIKERREELAVMEVKDTGKPVYEARMDVDSGW--QCLEYFAGLAPTIAGQHIQL----PGGSFMYSRREPLGVCVGIGAWNFPFQIACWKSAPALACGNAMVFKPSPLTPLTAVALAEIYTEAGLPPGLFNIVQGDGE-TGQLLCSHNDVAKVSCTGSVGTGVKVLQQTAP-RIKPVTLELGGKSPLIVFSDCDLDNAVKAALMGNFLSQGQVCSNATRVFVQRSVCERFLERLLDRVSAIRIGDPQRDSTTMGALISQSHLDRVLAYVQRAVQEGAKLVCGGKKYVPEDPSLKGGFFMTPCVLAECRDDMQAVREEIFGPVMAVLAFDTEEEVLQRANATDFGLAAGVFTKDLTRAHRVIAALQAGSCYINNYNVVLMEMPFGGYKMSGFGRENGMATVDYYTQLKTVYVEMGDVTCTL 525
BLAST of 10-formyltetrahydrofolate dehydrogenase vs. Ensembl Sea Lamprey
Match: aldh8a1 (aldehyde dehydrogenase 8 family, member A1 [Source:NCBI gene;Acc:447801]) HSP 1 Score: 280.026 bits (715), Expect = 8.488e-84 Identity = 186/488 (38.11%), Postives = 276/488 (56.56%), Query Frame = 3
Query: 1584 FINNEFVNSESGKEYDSKNPSDESVICRVSYSSXXXXXXXXXXXXXXFEFGEWGKMSARDRGRILYKLADLMEEHAEELATLESLDSGAVYTLALKTHIGMSIETFRYFAGWCDKIQGSTIPISNARPNKNLSFTKKEPIGVCGIITPWNYPLMMLAWKVAACLAAGNTVVLKPAQVTPLASLKFCELSVEAGFPPGVINVLPGSGAIAGTAISEHPDIRKLGFTGSTAIGQTIMSSCAKSNLKKCSLELGGKSPLIIFSDCDMDKAVKSACSSVFFNK-GENCIAAGRIF---VDVRIHDVFLKLVVEDVKKMKIGDPLDRSVDHGPQNHEIHLLKLLEFCDIGVKEGAKLVFG--------GKRCDRKGYFMEPTIFTSVTDDMYIAREESFGPIMIISKFYDIDEVIVRANKTEYGLASGVFTNDISKALRVADAIDAGTVFINTYNKTDVAAPFGGFKQSGFGKDLGQEALNEYLKTKTVTVEY 3011
+IN EFV SE+ DS PS +V CRV S + +V+ AV+AAK AF W S ++RGRIL +LA+L+E EELA ES D G A I + FR+FA +Q T + A + +T + P+GV G+I+PWN PL +L WK+A +A GNTVV KP+++T + + C L EAG PPGV+NV+ G+G AG A+ HPD+ + FTGSTA I A + K+ SLELGGK+P +IF+D D+D V + S F N+ G + IF V V+ F + K K+G P D + + GP + HL K+ + ++ ++G +++ G RC + GYF+ PT+ T V DD +EE FGP++ +S F D DE + R+N YGLA+ V++ D+++ RVA + AG V+ N + ++ PFGG K SG G++ +++ + KT+T+++
Sbjct: 13 YINGEFVASET--HVDSFEPSTGNVYCRVPDSGEAEVNAAVEAAKRAFP--AWAARSPQERGRILTRLAELIESRLEELAIAESHDQGKTVEHARTVDIPRAAYNFRFFA---SAVQHYTTECTQADHVGCMHYTVRSPVGVVGLISPWNLPLYLLTWKIAPAIALGNTVVAKPSELTSVTAWMLCMLLREAGVPPGVVNVVLGTGQKAGAALVGHPDVPAISFTGSTATACDITVRSAL-HCKRLSLELGGKNPAVIFADADLDACVATTVRSSFANQTGHVPSSLSAIFSHSVVVQCPRRFFR----TTKAWKVGPPDDFTSNMGPLISKEHLAKVRGYVELAERDGGQVLCGEGVDPLLLPPRC-QGGYFLAPTVITGVPDDSPAMQEEIFGPVVCVSPFEDEDEAVTRSNGVRYGLAAVVWSRDVARVHRVAKRLQAGIVWTNCWLIRELNLPFGGMKASGIGREGAKDSFEFFTDVKTITIKH 487
BLAST of 10-formyltetrahydrofolate dehydrogenase vs. Ensembl Sea Lamprey
Match: aldh5a1 (aldehyde dehydrogenase 5 family, member A1 (succinate-semialdehyde dehydrogenase) [Source:ZFIN;Acc:ZDB-GENE-070228-2]) HSP 1 Score: 275.404 bits (703), Expect = 6.114e-83 Identity = 157/418 (37.56%), Postives = 240/418 (57.42%), Query Frame = 3
Query: 1758 RDRGRILYKLADLMEEHAEELATLESLDSGAVYTLALKTHIGMSIETFRYFAGWCDKIQGSTIPISNARPNKNLSFTKKEPIGVCGIITPWNYPLMMLAWKVAACLAAGNTVVLKPAQVTPLASLKFCELSVEAGFPPGVINVLPGSGA---IAGTAISEHPDIRKLGFTGSTAIGQTIMSSCAKSNLKKCSLELGGKSPLIIFSDCDMDKAVKSACSSVFFNKGENCIAAGRIFVDVRIHDVFLKLVVEDVK-KMKIGDPLDRSVDHGPQNHEIHLLKLLEFCDIGVKEGAKLVFGGKRCDRKGYFMEPTIFTSVTDDMYIAREESFGPIMIISKFYDIDEVIVRANKTEYGLASGVFTNDISKALRVADAIDAGTVFINTYNKTDVAAPFGGFKQSGFGKDLGQEALNEYLKTKTV 2999
++RG +L + +++ ++ +ELA L + +SG +L + +F + G IP +A P++ + F+ +P+GV +ITPWN+P+ M+ KV A LAAG T V+KPA+ TPL++L +L+VEAG PPGV+NV+P S A G + HP + K+ FTGSTA G+ +M+ A +K+ S+ELGG +P I+F D+D AV+ SS F G+ C+ R+ V +HD F+ + V ++++G D GP +E L K+ V +GA++V GG R G F +PT+ VT +M AREE+FGP+ I KF +E I AN T GLA F+ D+++ RV++A++ G V N + V APFGG KQSG G++ Q+ + EY+ K V
Sbjct: 1 QERGALLKRWYEVILQNRQELAQLITAESGKPQQESLG-EVSYGAAFLEWFGEEARRAYGQIIP--SAAPDRRM-FSMYQPVGVAAMITPWNFPVAMITRKVGAALAAGCTAVVKPAEDTPLSALALAQLAVEAGLPPGVLNVVPCSRANVAAVGELLCTHPSVSKISFTGSTATGKVLMAH-AVGTVKRVSMELGGHAPFIVFESADLDAAVRGLLSSKFRFSGQTCVCPNRMLVQESVHDAFVSRLAHAVSTQLRVGPGADTGNTLGPLINEHALEKVERHVVDAVSQGARVVVGGARHALGGSFFQPTVLADVTPNMLCAREETFGPLAPIIKFKTEEEAIALANSTAMGLAGYFFSRDVAQVWRVSEALEVGMVGANEGLLSAVEAPFGGIKQSGLGREGAQQGMLEYMHVKYV 413
BLAST of 10-formyltetrahydrofolate dehydrogenase vs. Ensembl Sea Lamprey
Match: ENSPMAT00000003200.1 (pep scaffold:Pmarinus_7.0:GL477311:15162:38714:-1 gene:ENSPMAG00000002923.1 transcript:ENSPMAT00000003200.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 228.024 bits (580), Expect = 2.431e-68 Identity = 106/169 (62.72%), Postives = 129/169 (76.33%), Query Frame = 3
Query: 438 AMEAIDLGTKVFKIPKWRVNNQIIKEVFEEYRSINAELNVLAFCTQFIPMEVINAPKHRSIIYHPSLLPKHRGASAINWTLINGDLKGGLTIFWADDGLDTGPVLLQRECDVHINDTVDSLYSRFMMPEGIKAMVEAVRQIESGRAPAIAQYHPDHSYDQMVKKSTAEI 944
A+ A GT VFK P+WR + I EV E Y+S+ A+LNVL FC+QFIPM+VI+ P H SIIYHPSLLP+HRGASAINWTLI+GD +GGL++FWAD GLDTGP+LLQREC V NDTVDSLY+RF+ PEGIKAM EAV+ I G+AP I Q SY+ + K A++
Sbjct: 65 ALVADKEGTPVFKFPRWRTKGKPIPEVLEAYKSLGAQLNVLPFCSQFIPMDVIDHPSHGSIIYHPSLLPRHRGASAINWTLIHGDQRGGLSVFWADAGLDTGPLLLQRECRVEPNDTVDSLYNRFLYPEGIKAMTEAVQLIADGKAPRIPQTEEGASYEGIQHKEAAQV 233 HSP 2 Score: 74.3294 bits (181), Expect = 6.758e-15 Identity = 36/85 (42.35%), Postives = 56/85 (65.88%), Query Frame = 1
Query: 64 YNLKLFQHLHFHNFNPRMKIAIIGQSIFGAQVYKELKNEGHDIVGVFTIPDRNGRSDPLGIFYWE*GFTTLLMTSKKSQGRPLAQ 318
Y+L L +++ N ++K+A+IGQS+FG +VYK L+ EGH IVGVFTIPD NG+ DPL + + G +++G+P+ +
Sbjct: 9 YHLLLSFQVYYAN---KLKVAVIGQSLFGQEVYKSLRKEGHAIVGVFTIPDINGKPDPLALVADKEGTPVFKFPRWRTKGKPIPE 90
BLAST of 10-formyltetrahydrofolate dehydrogenase vs. Ensembl Yeast
Match: ALD5 (Mitochondrial aldehyde dehydrogenase; involved in regulation or biosynthesis of electron transport chain components and acetate formation; activated by K+; utilizes NADP+ as the preferred coenzyme; constitutively expressed [Source:SGD;Acc:S000000875]) HSP 1 Score: 434.491 bits (1116), Expect = 2.915e-141 Identity = 225/485 (46.39%), Postives = 319/485 (65.77%), Query Frame = 3
Query: 1551 NKMTFPIPHQIFINNEFVNSESGKEYDSKNPSDESVICRVSYSSXXXXXXXXXXXXXXFEFGEWGKMSARDRGRILYKLADLMEEHAEELATLESLDSGAVYTLALKTHIGMSIETFRYFAGWCDKIQGSTIPISNARPNKNLSFTKKEPIGVCGIITPWNYPLMMLAWKVAACLAAGNTVVLKPAQVTPLASLKFCELSVEAGFPPGVINVLPGSGAIAGTAISEHPDIRKLGFTGSTAIGQTIMSSCAKSNLKKCSLELGGKSPLIIFSDCDMDKAVKSACSSVFFNKGENCIAAGRIFVDVRIHDVFLKLVVEDVKKMKIGDPLDRSVDHGPQNHEIHLLKLLEFCDIGVKEGAKLVFGGKRCDRKGYFMEPTIFTSVTDDMYIAREESFGPIMIISKFYDIDEVIVRANKTEYGLASGVFTNDISKALRVADAIDAGTVFINTYNKTDVAAPFGGFKQSGFGKDLGQEALNEYLKTKTVTV 3005
N T+ P +FIN EFV S+ K +D NPS+E I V + + DVD AV AAK+AFE +W + R + L+ LADL+E+H E LA +ES+D+G A + + + + R GW DKI G+ I + +++ KEP+GVCG I PWN+PL+M +WK+ LA GNTVVLKPA+ TPL++L +L EAG P GV+N+LPGSG + G +S HPD++K+ FTGSTA G+ IM A + +KK +LELGGKSP I+F+D D+DKAVK+ +F+N GE C A RI++ +++ L+ + + + +K+GDP D V G Q + L K+L++ D+ EGA+LV GG R KGYF++PT+F V +DM I +EE FGPI+ +SKF +DEVI AN ++YGLA+G+ TNDI+KA+ V+ + AGTV+INTYN PFGGF QSG G+++G+ AL+ Y +TK+V +
Sbjct: 36 NGFTYEQPTGLFINGEFVASKQKKTFDVINPSNEEKITTVYKAMEDDVDEAVAAAKKAFE-TKWSIVEPEVRAKALFNLADLVEKHQETLAAIESMDNGKSLFCA-RGDVALVSKYLRSCGGWADKIYGNVIDTGK----NHFTYSIKEPLGVCGQIIPWNFPLLMWSWKIGPALATGNTVVLKPAETTPLSALFASQLCQEAGIPAGVVNILPGSGRVVGERLSAHPDVKKIAFTGSTATGRHIMKVAADT-VKKVTLELGGKSPNIVFADADLDKAVKNIAFGIFYNSGEVCCAGSRIYIQDTVYEEVLQKLKDYTESLKVGDPFDEEVFQGAQTSDKQLHKILDYVDVAKSEGARLVTGGARHGSKGYFVKPTVFADVKEDMRIVKEEVFGPIVTVSKFSTVDEVIAMANDSQYGLAAGIHTNDINKAVDVSKRVKAGTVWINTYNNFHQNVPFGGFGQSGIGREMGEAALSNYTQTKSVRI 513
BLAST of 10-formyltetrahydrofolate dehydrogenase vs. Ensembl Yeast
Match: ALD4 (Mitochondrial aldehyde dehydrogenase; required for growth on ethanol and conversion of acetaldehyde to acetate; phosphorylated; activity is K+ dependent; utilizes NADP+ or NAD+ equally as coenzymes; expression is glucose repressed; can substitute for cytosolic NADP-dependent aldehyde dehydrogenase when directed to the cytosol; human homolog ALDH2 can complement yeast ald4 mutant [Source:SGD;Acc:S000005901]) HSP 1 Score: 424.476 bits (1090), Expect = 2.009e-137 Identity = 217/483 (44.93%), Postives = 317/483 (65.63%), Query Frame = 3
Query: 1551 NKMTFPIPHQIFINNEFVNSESGKEYDSKNPSDESVICRVSYSSXXXXXXXXXXXXXXFEFGEWGKMSARDRGRILYKLADLMEEHAEELATLESLDSGAVYTLALKTHIGMSIETFRYFAGWCDKIQGSTIPISNARPNKNLSFTKKEPIGVCGIITPWNYPLMMLAWKVAACLAAGNTVVLKPAQVTPLASLKFCELSVEAGFPPGVINVLPGSGAIAGTAISEHPDIRKLGFTGSTAIGQTIMSSCAKSNLKKCSLELGGKSPLIIFSDCDMDKAVKSACSSVFFNKGENCIAAGRIFVDVRIHDVFLKLVVEDVKKMKIGDPLDRSVDHGPQNHEIHLLKLLEFCDIGVKEGAKLVFGGKRCDRKGYFMEPTIFTSVTDDMYIAREESFGPIMIISKFYDIDEVIVRANKTEYGLASGVFTNDISKALRVADAIDAGTVFINTYNKTDVAAPFGGFKQSGFGKDLGQEALNEYLKTKTV 2999
N + + P +FINN+FV S+ K ++ NPS E IC + + DV+ AV+AA AF G W + DRG+ LY+LA+L+E+ + +A++E+LD+G + + + + + I + AG+ DKI G I + S+TK++P+GVCG I PWN+PL+M AWK+A L GNTVVLK A+ TPL++L + +AG PPGVIN++ G G I G AI+ HP I+K+ FTGSTA G+ I S A + LKK +LELGGKSP I+F+D ++ KAV++ +++N GE C A R++V+ I+D F++ + +K+GDP D S G Q ++ L K+L++ DIG EGA L+ GG+R KGYF++PT+F V +DM I +EE FGP++ ++KF DEVI AN +EYGLA+G+ T++I+ AL+VAD ++AGTV+INTYN A PFGGF SG G+++ +AL YL+ K V
Sbjct: 37 NGLEYEQPTGLFINNKFVPSKQNKTFEVINPSTEEEICHIYEGREDDVEEAVQAADRAFSNGSWNGIDPIDRGKALYRLAELIEQDKDVIASIETLDNGKAISSS-RGDVDLVINYLKSSAGFADKIDGRMIDTGRT----HFSYTKRQPLGVCGQIIPWNFPLLMWAWKIAPALVTGNTVVLKTAESTPLSALYVSKYIPQAGIPPGVINIVSGFGKIVGEAITNHPKIKKVAFTGSTATGRHIYQSAA-AGLKKVTLELGGKSPNIVFADAELKKAVQNIILGIYYNSGEVCCAGSRVYVEESIYDKFIEEFKAASESIKVGDPFDESTFQGAQTSQMQLNKILKYVDIGKNEGATLITGGERLGSKGYFIKPTVFGDVKEDMRIVKEEIFGPVVTVTKFKSADEVINMANDSEYGLAAGIHTSNINTALKVADRVNAGTVWINTYNDFHHAVPFGGFNASGLGREMSVDALQNYLQVKAV 513
BLAST of 10-formyltetrahydrofolate dehydrogenase vs. Ensembl Yeast
Match: ALD6 (Cytosolic aldehyde dehydrogenase; activated by Mg2+ and utilizes NADP+ as the preferred coenzyme; required for conversion of acetaldehyde to acetate; constitutively expressed; locates to the mitochondrial outer surface upon oxidative stress [Source:SGD;Acc:S000005982]) HSP 1 Score: 406.757 bits (1044), Expect = 6.033e-131 Identity = 209/504 (41.47%), Postives = 316/504 (62.70%), Query Frame = 3
Query: 1518 KLHYDAV----IINANKMTFPIPHQIFINNEFVNSESGKEYDSKNPSDESVICRVSYSSXXXXXXXXXXXXXXFEFGEWGKMSARDRGRILYKLADLMEEHAEELATLESLDSGAVYTLALKTHIGMSIETFRYFAGWCDKIQGSTIPISNARPNKNLSFTKKEPIGVCGIITPWNYPLMMLAWKVAACLAAGNTVVLKPAQVTPLASLKFCELSVEAGFPPGVINVLPGSGAIAGTAISEHPDIRKLGFTGSTAIGQTIMSSCAKSNLKKCSLELGGKSPLIIFSDCDMDKAVKSACSSVFFNKGENCIAAGRIFVDVRIHDVFL---KLVVEDVKKMKIGDPLDRSVDHGPQNHEIHLLKLLEFCDIGVKEGAKLVFGGKRCDRKGYFMEPTIFTSVTDDMYIAREESFGPIMIISKFYDIDEVIVRANKTEYGLASGVFTNDISKALRVADAIDAGTVFINTYNKTDVAAPFGGFKQSGFGKDLGQEALNEYLKTKTVTVE 3008
KLH+D I N +T+ P +FINN+F+ ++ GK Y ++PS E+ +C VS ++ +DV+ A++ A AF EW R+RGR+L KLAD +E + ++++E+LD+G LA + + ++I R A + DK+ G TI + N FT EPIGVCG I PWN+P+MMLAWK+A LA GN +LKPA VTPL +L F L + G P GV+N++PG G G A++ P IRKL FTGST +G+++ ++SNLKK +LELGGKS ++F D ++ K + + + +F N G+ C + RI+V I+D L K +E ++K+G+P D++ G + ++ + DIG KEGAK++ GG++ KGYF+ PT+F V +DM I +EE FGP++ ++KF ++E + AN +E+GL SG+ T +S L+VA + AGTV+INTYN D PFGG KQSG+G+++G+E + Y + K V ++
Sbjct: 3 KLHFDTAEPVKITLPNGLTYEQPTGLFINNKFMKAQDGKTYPVEDPSTENTVCEVSSATTEDVEYAIECADRAFHDTEWATQDPRERGRLLSKLADELESQIDLVSSIEALDNGKTLALA-RGDVTIAINCLRDAAAYADKVNGRTINTGDGYMN----FTTLEPIGVCGQIIPWNFPIMMLAWKIAPALAMGNVCILKPAAVTPLNALYFASLCKKVGIPAGVVNIVPGPGRTVGAALTNDPRIRKLAFTGSTEVGKSVAVDSSESNLKKITLELGGKSAHLVFDDANIKKTLPNLVNGIFKNAGQICSSGSRIYVQEGIYDELLAAFKAYLE--TEIKVGNPFDKANFQGAITNRQQFDTIMNYIDIGKKEGAKILTGGEKVGDKGYFIRPTVFYDVNEDMRIVKEEIFGPVVTVAKFKTLEEGVEMANSSEFGLGSGIETESLSTGLKVAKMLKAGTVWINTYNDFDSRVPFGGVKQSGYGREMGEEVYHAYTEVKAVRIK 499
BLAST of 10-formyltetrahydrofolate dehydrogenase vs. Ensembl Yeast
Match: ALD2 (Cytoplasmic aldehyde dehydrogenase; involved in ethanol oxidation and beta-alanine biosynthesis; uses NAD+ as the preferred coenzyme; expression is stress induced and glucose repressed; very similar to Ald3p [Source:SGD;Acc:S000004780]) HSP 1 Score: 363.229 bits (931), Expect = 2.092e-114 Identity = 209/501 (41.72%), Postives = 295/501 (58.88%), Query Frame = 3
Query: 1527 YDAVIINANKMTFPIPHQIFINNEFVNSESGKEYDSKNPSDESVICRVSYSSXXXXXXXXXXXXXXFEFGEWGKMSARDRGRILYKLADLMEEHAEELATLESLDSGAVYTLALKTHIGMSIETFRYFAGWCDKI-QGSTIPISNARPNKNLSFTKKEPIGVCGIITPWNYPLMMLAWKVAACLAAGNTVVLKPAQVTPLASLKFCELSVEAGFPPGVINVLPGSGAIAGTAISEHPDIRKLGFTGSTAIGQTIMSSCAKSNLKKCSLELGGKSPLIIFSDCDMDKAVKSACSSVFFNKGENCIAAGRIFVDVRIHDVFLKLVVEDVKK----MKIGDPLDRSVDHGPQNHEIHLLKLLEFCDIGVKEGAKLVFGGKRCD---RKGYFMEPTIFTSVTDDMYIAREESFGPIMIISKFYDIDEVIVRANKTEYGLASGVFTNDISKALRVADAIDAGTVFINTYNKTDVAAPFGGFKQSGFGKDLGQEALNEYLKTKTVTV 3005
Y + I K++ P +FINNEF S GK ++ NP+ I +++KDVD AVKAA+ AF+ W K S+ RG L L L+EE + LA LE+LD+G Y K + ++ RYFAG DK +G+TIP++ + ++T K P GV I PWNYPL M WK+ LAAGNTV++KPA+ T L+ L F L +AGFPPGV+N++PG G++ G A++ H DI K+ FTGST +G ++ + +SNLK +LE GGKSP ++F D D+DKA+ + +F+N G+NC A R++V I+D F++ E KK DP D GP ++ + + G +E +F KGYF+ PTIFT V + ++E FGP++++SKF + D+ + AN T YGLAS VFT D+ KA A I AGTV+IN+ N DV PFGGFK SG G++LGQ ++ YL+TK V +
Sbjct: 5 YTDIEIPQLKISLKQPLGLFINNEFCPSSDGKTIETVNPATGEPITSFQAANEKDVDKAVKAARAAFD-NVWSKTSSEQRGIYLSNLLKLIEEEQDTLAALETLDAGKPYHSNAKGDLAQILQLTRYFAGSADKFDKGATIPLTFNK----FAYTLKVPFGVVAQIVPWNYPLAMACWKLQGALAAGNTVIIKPAENTSLSLLYFATLIKKAGFPPGVVNIVPGYGSLVGQALASHMDIDKISFTGSTKVGGFVLEASGQSNLKDVTLECGGKSPALVFEDADLDKAIDWIAAGIFYNSGQNCTANSRVYVQSSIYDKFVEKFKETAKKEWDVAGKFDPFDEKCIVGPVISSTQYDRIKSYIERGKREEKLDMFQTSEFPIGGAKGYFIPPTIFTDVPQTSKLLQDEIFGPVVVVSKFTNYDDALKLANDTCYGLASAVFTKDVKKAHMFARDIKAGTVWINSSNDEDVTVPFGGFKMSGIGRELGQSGVDTYLQTKAVHI 500
BLAST of 10-formyltetrahydrofolate dehydrogenase vs. Ensembl Yeast
Match: ALD3 (Cytoplasmic aldehyde dehydrogenase; involved in beta-alanine synthesis; uses NAD+ as the preferred coenzyme; very similar to Ald2p; expression is induced by stress and repressed by glucose [Source:SGD;Acc:S000004779]) HSP 1 Score: 351.288 bits (900), Expect = 6.856e-110 Identity = 208/506 (41.11%), Postives = 293/506 (57.91%), Query Frame = 3
Query: 1527 YDAVIINANKMTFPIPHQIFINNEFVNSESGKEYDSKNPSDESVICRVSYSSXXXXXXXXXXXXXXFEFGEWGKMSARDRGRILYKLADLMEEHAEELATLESLDSGAVYTLALKTHIGMSIETFRYFAGWCDKIQ-GSTIPISNARPNKNLSFTKKEPIGVCGIITPWNYPLMMLAWKVAACLAAGNTVVLKPAQVTPLASLKFCELSVEAGFPPGVINVLPGSGAIAGTAISEHPDIRKLGFTGSTAIGQTIMSSCAKSNLKKCSLELGGKSPLIIFSDCDMDKAVKSACSSVFFNKGENCIAAGRIFVDVRIHDVFLKLVVEDVKK----MKIGDPLDRSVDHGPQNHEIHLLKLLEFCDIGVKE-------GAKLVFGGKRCDRKGYFMEPTIFTSVTDDMYIAREESFGPIMIISKFYDIDEVIVRANKTEYGLASGVFTNDISKALRVADAIDAGTVFINTYNKTDVAAPFGGFKQSGFGKDLGQEALNEYLKTKTVTVE 3008
Y + I K++ P +FINNEF S GK ++ NP+ I +++KDVD AVKAA+ AF+ W K S+ RG L L L+EE + LA LE+LD+G + K + IE RY+AG DK G TIP++ + ++T K P GV I PWNYPL M K+ LAAGNTV++KPA+ T L+ L F L +AGFPPGV+NV+PG G++ G A+ H DI K+ FTGST +G +++ + +SNLK +LE GGKSP ++F D D+DKA++ + +FFN G+ C A R++V I+D F++ E KK DP D GP ++ + + G KE ++ GG KGYF+ PTIFT V + + R+E FGP++++SKF + D+ + AN T YGLAS VFT D+ KA A I AGTV+IN N+ + PFGGFK SG G++ G ++ YL+ K+V V+
Sbjct: 5 YTDIEIPQLKISLKQPLGLFINNEFCPSSDGKTIETVNPATGEPITSFQAANEKDVDKAVKAARAAFD-NVWSKTSSEQRGIYLSNLLKLIEEEQDTLAALETLDAGKPFHSNAKQDLAQIIELTRYYAGAVDKFNMGETIPLTFNK----FAYTLKVPFGVVAQIVPWNYPLAMACRKMQGALAAGNTVIIKPAENTSLSLLYFATLIKKAGFPPGVVNVIPGYGSVVGKALGTHMDIDKISFTGSTKVGGSVLEASGQSNLKDITLECGGKSPALVFEDADLDKAIEWVANGIFFNSGQICTANSRVYVQSSIYDKFVEKFKETAKKEWDVAGKFDPFDEKCIVGPVISSTQYDRIKSYIERGKKEEKLDMFQTSEFPIGGA----KGYFIPPTIFTDVPETSKLLRDEIFGPVVVVSKFTNYDDALKLANDTCYGLASAVFTKDVKKAHMFARDIKAGTVWINQTNQEEAKVPFGGFKMSGIGRESGDTGVDNYLQIKSVHVD 501
BLAST of 10-formyltetrahydrofolate dehydrogenase vs. Ensembl Nematostella
Match: EDO46151 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RQR3]) HSP 1 Score: 1045.8 bits (2703), Expect = 0.000e+0 Identity = 510/854 (59.72%), Postives = 643/854 (75.29%), Query Frame = 3
Query: 459 GTKVFKIPKWRVNNQIIKEVFEEYRSINAELNVLAFCTQFIPMEVINAPKHRSIIYHPSLLPKHRGASAINWTLINGDLKGGLTIFWADDGLDTGPVLLQRECDVHINDTVDSLYSRFMMPEGIKAMVEAVRQIESGRAPAIAQYHPDHSYDQM-VKKSTAEINWNQSGLSLHNFIRGHDKVPGAWSWINGQKVTFYGSQLWYHDVVHDGPSLAIQGLSDPAVLHNHGLLIRGSDNQWINIAQLKFEDTGKTVQASKYGKGDEITTMADLSEDERAMEIPLMKIWKSILMGSDIEPESDFFKLGGTSMDVTRIIEQIKCNFNVELKIDHIYLYSTFDTLFKWIVLRKRGGGSQKKLHYDAVIINANKMTFPIPHQIFINNEFVNSESGKEYDSKNPSDESVICRVSYSSXXXXXXXXXXXXXXFEFGEWGKMSARDRGRILYKLADLMEEHAEELATLESLDSGAVYTLALKTHIGMSIETFRYFAGWCDKIQGSTIPISNARPNKNLSFTKKEPIGVCGIITPWNYPLMMLAWKVAACLAAGNTVVLKPAQVTPLASLKFCELSVEAGFPPGVINVLPGSGAIAGTAISEHPDIRKLGFTGSTAIGQTIMSSCAKSNLKKCSLELGGKSPLIIFSDCDMDKAVKSACSSVFFNKGENCIAAGRIFVDVRIHDVFLKLVVEDVKKMKIGDPLDRSVDHGPQNHEIHLLKLLEFCDIGVKEGAKLVFGGKRCDRKGYFMEPTIFTSVTDDMYIAREESFGPIMIISKF--YDIDEVIVRANKTEYGLASGVFTNDISKALRVADAIDAGTVFINTYNKTDVAAPFGGFKQSGFGKDLGQEALNEYLKTKTVTVEY 3011
G KVFK P+WR + I EV ++Y++ AELNV+ FC+QFIPM VI+ PKH SIIYHPSLLP+HRGASAINWTL+ GD K G +IFWADDGLDTGP+LLQ+ V NDTVD+LY+RF+ PEGIK MVEAV I +G+AP I Q +YD++ KK A+INWNQ+ +LHNFIRG+DK+PGAW+ ING++VTFYGS+L G + I GL PA++H G+ I GSD + + + L+ G+ ++ASKYG+ +E +L+E+E A+E L IW IL DI E+DFF G SMDV R++E++K V ++ + I + + N MT +PHQ+FIN EFV+S GK +++ NP+D +V+ +VS ++ +DVD AV AAKEAF G WG M+ARDR ++ +LADLME+H EELAT+ESLDSGAVYTLALKTH+GMSI+T RYFAGWCDKIQG T+P++NA+PN+NL +TK+EPIGVCG+I PWNYPLMMLAWK++ LAAGNTVVLKPAQVTP+ +LKF EL+ AGFP GVIN+LPGSG++ G I EHPD+RKLGFTGST +G+ IM SCA SNLKKCSLELGGKSPLIIFSDCDM++AV+ + FNKGENCIAAGR+FV+ IHD F+ +V+++KK+KIGDPLD + DHGPQNH+ HL L+E+ GV+EGAKLV+GG+ DR G+F EP +FT+V DDM+IA+EESFGP++IISKF D++ V+ AN TEYGLASGVFT D+SKALRVADA++AGT F+NTYNKTDVAAPFGG KQSGFGKDLG EALNEYLKTK +T+EY
Sbjct: 53 GVKVFKFPRWRTKGEPIAEVVDKYKACGAELNVMPFCSQFIPMNVIDFPKHGSIIYHPSLLPRHRGASAINWTLMEGDKKAGFSIFWADDGLDTGPILLQKSIQVDPNDTVDTLYNRFLYPEGIKGMVEAVELIANGKAPRITQPEEGATYDKIWKKKEVAKINWNQNAATLHNFIRGNDKLPGAWALINGEEVTFYGSKLGPKGKTPKGCEVEIDGLDRPAIVHKDGMTIIGSDEKMLTVKTLQLAG-GRMIEASKYGQEEEHMAPLELNEEETAIEGKLKAIWAGILANPDINEETDFFNAGAGSMDVARLVEEVKQKCGVVIEPEEIDM-------------------------------DVNYMTIHMPHQLFINGEFVDSHHGKTFNTINPTDGTVLAQVSLATHEDVDDAVDAAKEAFYNGPWGSMNARDRATLMNRLADLMEQHKEELATIESLDSGAVYTLALKTHVGMSIDTVRYFAGWCDKIQGLTVPVNNAKPNRNLCYTKREPIGVCGLIVPWNYPLMMLAWKISPLLAAGNTVVLKPAQVTPMTALKFAELAARAGFPKGVINILPGSGSVVGNRICEHPDVRKLGFTGSTPVGKAIMESCATSNLKKCSLELGGKSPLIIFSDCDMERAVRQGMMACLFNKGENCIAAGRLFVEESIHDEFVNRLVDELKKLKIGDPLDTATDHGPQNHKAHLDSLVEYVKRGVEEGAKLVYGGRHLDRPGFFFEPAVFTNVEDDMFIAKEESFGPVVIISKFDDGDVEGVLESANGTEYGLASGVFTKDMSKALRVADALEAGTCFVNTYNKTDVAAPFGGCKQSGFGKDLGMEALNEYLKTKVITIEY 874 HSP 2 Score: 63.5438 bits (153), Expect = 4.031e-10 Identity = 31/69 (44.93%), Postives = 45/69 (65.22%), Query Frame = 1
Query: 112 RMKIAIIGQSIFGAQVYKELKNEGHDIVGVFTIPDRNGRSDPLGIFYWE*GFTTLLMTSKKSQGRPLAQ 318
++KIAIIGQS FG +VY+ L+ +GH+IVGVFT+PD G+ D L E G +++G P+A+
Sbjct: 3 QLKIAIIGQSQFGLEVYRNLRIKGHEIVGVFTVPDIKGKPDILAAGAEEDGVKVFKFPRWRTKGEPIAE 71
BLAST of 10-formyltetrahydrofolate dehydrogenase vs. Ensembl Nematostella
Match: EDO47653 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RLS5]) HSP 1 Score: 447.973 bits (1151), Expect = 8.589e-146 Identity = 229/478 (47.91%), Postives = 315/478 (65.90%), Query Frame = 3
Query: 1575 HQIFINNEFVNSESGKEYDSKNPSDESVICRVSYSSXXXXXXXXXXXXXXFEFGE-WGKMSARDRGRILYKLADLMEEHAEELATLESLDSGAVYTLALKTHIGMSIETFRYFAGWCDKIQGSTIPISNARPNKNLSFTKKEPIGVCGIITPWNYPLMMLAWKVAACLAAGNTVVLKPAQVTPLASLKFCELSVEAGFPPGVINVLPGSGAIAGTAISEHPDIRKLGFTGSTAIGQTIMSSCAKSNLKKCSLELGGKSPLIIFSDCDMDKAVKSACSSVFFNKGENCIAAGRIFVDVRIHDVFLKLVVEDVKKMKIGDPLDRSVDHGPQNHEIHLLKLLEFCDIGVKEGAKLVFGGKRCDRKGYFMEPTIFTSVTDDMYIAREESFGPIMIISKFYDIDEVIVRANKTEYGLASGVFTNDISKALRVADAIDAGTVFINTYNKTDVAAPFGGFKQSGFGKDLGQEALNEYLKTKTVTV 3005
+Q+FINN+FVNS SGK + + NPS VIC V+ K DVDIAVKAA+ AF+ G W M A DRGR+L +LADL+E LA+LE+LD+G Y + + +I+ +RY+AGW DKI G TIP+ + +T+ EP+GV G + PWN+PL+M AWK+ LA GNTVV+KPA+ TPL +L L EAGFP GV+N++PG G AG AI+ H D+ K+ FTGST +G I S SNLK +LELGGKSP I+ +D D+D AV + ++FFN+G+ C A R FV I+D F++ V+ K +G+P D GPQ + K+L + G KEGAKL GG R KGYF++PT+F+ V D+M IA+EE FGP+M I +F D++++I RANKT YGLA V T ++ AL +++++ GTV++N Y+ APFGG+K SG G++LG+ L +Y + KTVT+
Sbjct: 43 NQVFINNQFVNSVSGKTFQTFNPSTGEVICDVAEGDKHDVDIAVKAAQSAFKLGSPWRTMDASDRGRLLNRLADLIERDKAYLASLETLDNGKPYNDSFNVDLEFTIKCYRYYAGWADKIHGKTIPLDGSF----FCYTRHEPVGVVGQVIPWNFPLLMQAWKLGPALACGNTVVMKPAEQTPLTALYVASLIAEAGFPEGVVNIVPGFGPTAGGAIASHMDVDKIAFTGSTEVGHIIQQSAGASNLKNVTLELGGKSPNIVLADSDVDFAVDMSHFALFFNQGQCCCAGSRTFVQEGIYDEFVEKSVQRAKNRVVGNPFDLKTQQGPQVDGEQMTKILNLIESGRKEGAKLEVGGDRAGDKGYFIQPTVFSDVQDNMRIAQEEIFGPVMQIFRFKDMNDIIERANKTTYGLAGSVMTKNLENALMLSNSLRVGTVWVNCYDALSAQAPFGGYKMSGVGRELGEYGLQQYSEVKTVTI 516
BLAST of 10-formyltetrahydrofolate dehydrogenase vs. Ensembl Nematostella
Match: EDO45538 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RSB4]) HSP 1 Score: 437.573 bits (1124), Expect = 3.113e-142 Identity = 236/478 (49.37%), Postives = 321/478 (67.15%), Query Frame = 3
Query: 1578 QIFINNEFVNSESGKEYDSKNPSDESVICRVSYSSXXXXXXXXXXXXXXFEFGE-WGKMSARDRGRILYKLADLMEEHAEELATLESLDSGAVYTLALKTHIGMSIETFRYFAGWCDKIQGSTIPISNARPNKNLSFTKKEPIGVCGIITPWNYPLMMLAWKVAACLAAGNTVVLKPAQVTPLASLKFCELSVEAGFPPGVINVLPGSGAIAGTAISEHPDIRKLGFTGSTAIGQTIMSSCAKSNLKKCSLELGGKSPLIIFSDCDMDKAVKSACSSVFFNKGENCIAAGRIFVDVRIHDVFLKLVVEDVKKMKIGDPLDRSVDHGPQNHEIHLLKLLEFCDIGVKEGAKLVFGGKRCDRKGYFMEPTIFTSVTDDMYIAREESFGPIMIISKFYDIDEVIVRANKTEYGLASGVFTNDISKALRVADAIDAGTVFINTYNKTDVAAPFGGFKQSGFGKDLGQEALNEYLKTKTVTVE 3008
++FINNEFV+ SGK + + NP+ IC +S K+DVD AVKAAKEAF+ G W M A RG++LYKLA L++ LA+LE++DSG +++ ++ + S FRY+AGW DK+ G TIP +T+ EP+G+ G ITPWN+PL M + K+A LA GN V+LKPA+ TPL +L FC L EAGFP GV+NV+PG G AG AI+ H DI K+ FTGST +G+ I + AKSNLK+ +LELGGKSP I+F+D DMD AV+ A ++FFN+G+ C A R FV I+D F+K V+ K +GDP D SV+ GPQ + K+++ + G KEGAK+ GG R KG+F++PT+F+ VTDDM IA+EE FGP+ + KF +DEVI RAN T YGLA+GVFT +I A+ V+ + AGTV+IN Y APFGG+K SG+G++ G+ + Y + KTVT++
Sbjct: 17 KLFINNEFVDCTSGKVFPTINPTTGEKICDISEGDKEDVDKAVKAAKEAFKLGSAWRTMDASMRGKLLYKLAQLIDRDIAYLASLETIDSGKLFSDSVG-DMQSSANCFRYYAGWADKVTGKTIPADGPY----FVYTRHEPVGLVGAITPWNFPLNMASVKIAPALACGNVVILKPAEQTPLTALYFCALVKEAGFPAGVVNVIPGYGPTAGAAITTHLDIDKVSFTGSTEVGRLIQEASAKSNLKRLTLELGGKSPNIVFADSDMDYAVEMAHEALFFNQGQCCSAGSRTFVQDTIYDEFVKKSVKRAKARTVGDPFD-SVEQGPQIDQEQFDKIMDLIESGKKEGAKMQCGGARHGNKGFFIQPTVFSDVTDDMRIAKEEIFGPVQQLIKFKSVDEVIERANNTTYGLAAGVFTKNIDTAIAVSSGLRAGTVWINCYECGAPQAPFGGYKMSGYGREWGEYGVLPYCEVKTVTMK 488
BLAST of 10-formyltetrahydrofolate dehydrogenase vs. Ensembl Nematostella
Match: EDO36183 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SJA5]) HSP 1 Score: 410.223 bits (1053), Expect = 2.208e-132 Identity = 229/436 (52.52%), Postives = 286/436 (65.60%), Query Frame = 3
Query: 1578 QIFINNEFVNSESGKEYDSKNPSDESVICRVSYSSXXXXXXXXXXXXXXFEFGE-WGKMSARDRGRILYKLADLMEEHAEELATLESLDSGAVYTLALKTHIGMSIETFRYFAGWCDKIQGSTIPISNARPNKNLSFTKKEPIGVCGIITPWNYPLMMLAWKVAACLAAGNTVVLKPAQVTPLASLKFCELSVEAGFPPGVINVLPGSGAIAGTAISEHPDIRKLGFTGSTAIGQTIMSSCAKSNLKKCSLELGGKSPLIIFSDCDMDKAVKSACSSVFFNKGENCIAAGRIFVDVRIHDVFLKLVVEDVKKMKIGDPLDRSVDHGPQNHEIHLLKLLEFCDIGVKEGAKLVFGGKRCDRKGYFMEPTIFTSVTDDMYIAREESFGPIMIISKFYDIDEVIVRANKTEYGLASGVFTNDISKALRVADAIDAGTVF 2882
Q+FINNEFV+S SGK + + NP+ E IC VS + K DVDIAV AAKEAF+ G W M A RG LYKLADL E A+ LA LES D G V A K + I FRY+AGW DK+ G TIP ++T+ EP+GV G ITPWN+PL+M K+A LA G V+LKPA+ TPL +L L EAGFP GV+NVLPG G AG AIS H I K+ FTGST +G+ I + AKSNLK+ +LELGGKSP I+F+D D+D AV+ +C +F N+G+ C A RIFV+ IHD F++ V K +GDPL+ GPQ E K+L + G ++GAK+ GG R KGYF+EPT+F+ V DDM IA+EE FGP+M I KF +I+EVI RAN T YGLA VF+ DI KAL VA +I AGT++
Sbjct: 10 QLFINNEFVDSVSGKTFPTLNPATEEKICDVSEADKADVDIAVAAAKEAFKLGSVWRTMDASARGHFLYKLADLCERDADYLARLESYDGGKVINEA-KIDVQGMISCFRYYAGWADKVTGKTIPADGPF----FTYTRHEPVGVVGAITPWNFPLLMEGLKLAPALACGCVVILKPAEQTPLTALYLASLVKEAGFPTGVVNVLPGYGPTAGAAISSHMGIDKISFTGSTEVGRLIQETAAKSNLKRVTLELGGKSPNIVFADADLDWAVEMSCLGLFINQGQCCCAGTRIFVEESIHDEFVRQCVARAKARVVGDPLEEKTVQGPQVDEEQFNKILGLIESGKQQGAKVECGGGRHGNKGYFVEPTVFSGVQDDMRIAKEEIFGPVMQILKFNEINEVIRRANDTTYGLAGAVFSKDIDKALMVAHSIQAGTMW 440
BLAST of 10-formyltetrahydrofolate dehydrogenase vs. Ensembl Nematostella
Match: EDO34362 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SPJ4]) HSP 1 Score: 347.821 bits (891), Expect = 1.106e-108 Identity = 186/462 (40.26%), Postives = 277/462 (59.96%), Query Frame = 3
Query: 1638 NPSDESVICRVSYSSXXXXXXXXXXXXXXFEFGEWGKMSARDRGRILYKLADLMEEHAEELATLESLDSGAVYTLALKTHIGMSIETFRYFAGWCDKIQGSTIPISNARPNKNLSFTKKEPIGVCGIITPWNYPLMMLAWKVAACLAAGNTVVLKPAQVTPLASLKFCELSVEAGFPPGVINVLPGSGAIAGTAISEHPDIRKLGFTGSTAIGQTIMSSCAKSNLKKCSLELGGKSPLIIFSDCDMDKAVKSACSSVFFNKGENCIAAGRIFVDVRIHDVFLKLVVEDVKKMKIGDPLDRSVDHGPQNHEIHLLKLLEFCDIGVKEGAKLVFGGKRCD-----RKGYFMEPTIFTSVTDDMYIAREESFGPIMIISKFYDIDEVIVRANKTEYGLASGVFTNDISKALRVADAIDAGTVFINTYNKTDVAAPFGGFKQSGFGKDLGQEALNEYLKTKTVTVE 3008
+PS + C V S K +V AV +A++AF+ W +S +RGRIL + L+ + E++A +E D+G + AL + + Y+AG + G + + PN + ++T++EP+GV G I WNYP+ WK+A +A GNT+V KP+ +TP+ ++ ++ EAG PPGV+N++ G G G +S+ P++ K+ FTGS GQ IM+SCA +K +LELGGKSPLIIF D DM AV A + F ++G+ C R+FV+ I D FL+ VVE K +++GDP+ G HL K+L++ IG EGAK++ GG+R GY+M P + TDDM + +EE FGP+M + F +E + RAN T +GLA G+FT D+++A RV ++ AGT +IN++N T V PFGG+K SGFG++ G A+ Y + KTV VE
Sbjct: 5 DPSTGHISCEVKGSGKTEVKRAVLSARKAFK--TWSVLSGSERGRILGDASRLVRKRREDIAKVEVHDNGKPFHEAL-WDVDNVADVLEYYAGVAPTLSGQHVQL----PNGSFAYTRREPLGVVGGIGAWNYPIQTACWKIAPAIACGNTIVYKPSPLTPMNAVALADILTEAGVPPGVVNIIQGGGE-TGEMLSKDPNVAKVSFTGSVPTGQKIMASCA-DGIKHVTLELGGKSPLIIFKDADMANAVSGALMANFLSQGQVCSNGTRVFVEDSIKDEFLEKVVERTKNIRVGDPMAPDTQMGAMISSAHLNKVLDYVQIGKDEGAKVLCGGERLHLPEPLTSGYYMSPCVMAECTDDMTVVKEEIFGPVMTVLTFQTEEEAVTRANNTTFGLAGGIFTRDLNRAHRVIGSLQAGTCWINSFNITPVEVPFGGYKMSGFGREGGTAAVEHYTQLKTVYVE 457
BLAST of 10-formyltetrahydrofolate dehydrogenase vs. Ensembl Medaka
Match: aldh1l2 (aldehyde dehydrogenase 1 family member L2 [Source:NCBI gene;Acc:101167504]) HSP 1 Score: 1101.66 bits (2848), Expect = 0.000e+0 Identity = 538/862 (62.41%), Postives = 672/862 (77.96%), Query Frame = 3
Query: 438 AMEAIDLGTKVFKIPKWRVNNQIIKEVFEEYRSINAELNVLAFCTQFIPMEVINAPKHRSIIYHPSLLPKHRGASAINWTLINGDLKGGLTIFWADDGLDTGPVLLQRECDVHINDTVDSLYSRFMMPEGIKAMVEAVRQIESGRAPAIAQYHPDHSYDQMVKKSTAEINWNQSGLSLHNFIRGHDKVPGAWSWINGQKVTFYGSQLWYHDVVHDGPSLAIQGLSDPAVLHNHGLLIRGSDNQWINIAQLKFEDTGKTVQASKYGKGDEITTMADLSEDERAMEIPLMKIWKSILMG-SDIEPESDFFKLGGTSMDVTRIIEQIKCN-FNVELKIDHIYLYSTFDTLFKWIVLRKRGGGSQKKLHYDAVIINANKMTFPIPHQIFINNEFVNSESGKEYDSKNPSDESVICRVSYSSXXXXXXXXXXXXXXFEFGEWGKMSARDRGRILYKLADLMEEHAEELATLESLDSGAVYTLALKTHIGMSIETFRYFAGWCDKIQGSTIPISNARPNKNLSFTKKEPIGVCGIITPWNYPLMMLAWKVAACLAAGNTVVLKPAQVTPLASLKFCELSVEAGFPPGVINVLPGSGAIAGTAISEHPDIRKLGFTGSTAIGQTIMSSCAKSNLKKCSLELGGKSPLIIFSDCDMDKAVKSACSSVFFNKGENCIAAGRIFVDVRIHDVFLKLVVEDVKKMKIGDPLDRSVDHGPQNHEIHLLKLLEFCDIGVKEGAKLVFGGKRCDRKGYFMEPTIFTSVTDDMYIAREESFGPIMIISKFY--DIDEVIVRANKTEYGLASGVFTNDISKALRVADAIDAGTVFINTYNKTDVAAPFGGFKQSGFGKDLGQEALNEYLKTKTVTVEY 3011
A+ A GT +FK P+WR Q + EV + Y+S+ AELNV+ FC+QFIPM VI+ PKH SIIYHPS+LP HRGASAINWTLI+GD K G T+FWADDGLDTGP+LLQREC V +DTVD+LY+RF+ PEGIKAMVE+V+ I G+AP I Q SY+ + +KS A ++ Q ++HN+IRGHDKVPGAW+ I GQ VTFYGS + V P L I+G S P ++ +GL++ G+D + + + L+FED GK + ASKY E +++ +L+ +E+ M + IWK+IL I +DFFK G SMDV R++E++K V+L+ + +Y+ +TF + V + RG +++L D N MT +P+Q FIN +F ++E GK Y + NP+D SVIC+VSY++ DVD AV AAKEAF+ G WG+M+ RDRG +LYKLADLMEEH EELAT+ES+DSGAVYTLALKTH+GMSI+TFRYFAGWCDKIQG TIPI+ ARPN+NL+FTKKEP+GVC I+ PWNYPLMMLAWK AACLAAGNT+VLKPAQVTPL +LKF ELSV+AG P GVIN+LPGSG + G +S+HPDIRKLGFTGST +G+ IM SCA SNLKK SLELGGKSPLIIFSDCDMDKAV+ SSVFFNKGENCIAAGR+FV+ IHD +++ VVE++ KMKIGDPLDRS DHGPQNH+ HL KLLE+C+IGVKEGA LV+GGK+ DR G+FM+PT+FT V D M+IA+EESFGP+M++SKF D+D V+ RAN TEYGLASGVFT DI+KA+ V++ ++AGTVF+NTYNKTDVA+PFGGFKQSGFGKDLG++AL+EYLKTK VTVEY
Sbjct: 65 AVAAEKDGTPLFKFPRWRNKGQPLPEVVDAYKSVGAELNVMPFCSQFIPMNVIDHPKHGSIIYHPSILPLHRGASAINWTLIHGDEKAGFTVFWADDGLDTGPILLQRECAVEPDDTVDTLYNRFLFPEGIKAMVESVQLIADGKAPRIPQPEEGASYEGIQRKSNARVDLAQPAKAIHNWIRGHDKVPGAWALIGGQSVTFYGSSMLSGSVPAGQP-LEIEGASQPGIISKNGLVLFGNDGKALLVKNLQFED-GKMIPASKYFSSGENSSV-ELTNEEKQMAEEIRNIWKAILSNVPAIVDTTDFFKSGAASMDVVRLVEEVKQKCAGVQLQNEDVYMATTFQDFIQIFVRKLRGEDQEEELTIDYATKEVNNMTVKMPYQCFINGKFEDAEDGKTYSTINPTDGSVICKVSYAAVGDVDRAVAAAKEAFDNGPWGRMNPRDRGSLLYKLADLMEEHQEELATIESIDSGAVYTLALKTHVGMSIQTFRYFAGWCDKIQGKTIPINQARPNRNLTFTKKEPLGVCAIVIPWNYPLMMLAWKSAACLAAGNTLVLKPAQVTPLTALKFAELSVKAGIPKGVINILPGSGGMVGQRLSDHPDIRKLGFTGSTPVGKQIMKSCALSNLKKVSLELGGKSPLIIFSDCDMDKAVRMGMSSVFFNKGENCIAAGRLFVEESIHDEYIRRVVEEIMKMKIGDPLDRSTDHGPQNHKAHLDKLLEYCEIGVKEGATLVYGGKQVDRPGFFMQPTVFTDVEDHMFIAKEESFGPVMVVSKFRNGDVDGVLQRANDTEYGLASGVFTRDINKAMYVSEQLEAGTVFVNTYNKTDVASPFGGFKQSGFGKDLGEDALSEYLKTKAVTVEY 923 HSP 2 Score: 75.8702 bits (185), Expect = 2.122e-13 Identity = 30/74 (40.54%), Postives = 51/74 (68.92%), Query Frame = 1
Query: 97 HNFNPRMKIAIIGQSIFGAQVYKELKNEGHDIVGVFTIPDRNGRSDPLGIFYWE*GFTTLLMTSKKSQGRPLAQ 318
H + ++K+AIIGQS+FG +VY L+ +GH +VGVFT+PD++G++DPL + + G +++G+PL +
Sbjct: 17 HYYQKKLKLAIIGQSLFGQEVYSSLRKQGHKVVGVFTVPDKDGKADPLAVAAEKDGTPLFKFPRWRNKGQPLPE 90
BLAST of 10-formyltetrahydrofolate dehydrogenase vs. Ensembl Medaka
Match: aldh1l1 (cytosolic 10-formyltetrahydrofolate dehydrogenase [Source:NCBI gene;Acc:101174660]) HSP 1 Score: 1097.8 bits (2838), Expect = 0.000e+0 Identity = 551/862 (63.92%), Postives = 665/862 (77.15%), Query Frame = 3
Query: 438 AMEAIDLGTKVFKIPKWRVNNQIIKEVFEEYRSINAELNVLAFCTQFIPMEVINAPKHRSIIYHPSLLPKHRGASAINWTLINGDLKGGLTIFWADDGLDTGPVLLQRECDVHINDTVDSLYSRFMMPEGIKAMVEAVRQIESGRAPAIAQYHPDHSYDQMVKKSTAEINWNQSGLSLHNFIRGHDKVPGAWSWINGQKVTFYGSQLWYHDVVHDGPSLAIQGLSDPAVLHNHGLLIRGSDNQWINIAQLKFEDTGKTVQASKYGKGDEITTMADLSEDERAMEIPLMKIWKSILMG-SDIEPESDFFKLGGTSMDVTRIIEQIKC-NFNVELKIDHIYLYSTFDTLFKWIVLRKRGGGSQKKLHYDAVIINANKMTFPIPHQIFINNEFVNSESGKEYDSKNPSDESVICRVSYSSXXXXXXXXXXXXXXFEFGEWGKMSARDRGRILYKLADLMEEHAEELATLESLDSGAVYTLALKTHIGMSIETFRYFAGWCDKIQGSTIPISNARPNKNLSFTKKEPIGVCGIITPWNYPLMMLAWKVAACLAAGNTVVLKPAQVTPLASLKFCELSVEAGFPPGVINVLPGSGAIAGTAISEHPDIRKLGFTGSTAIGQTIMSSCAKSNLKKCSLELGGKSPLIIFSDCDMDKAVKSACSSVFFNKGENCIAAGRIFVDVRIHDVFLKLVVEDVKKMKIGDPLDRSVDHGPQNHEIHLLKLLEFCDIGVKEGAKLVFGGKRCDRKGYFMEPTIFTSVTDDMYIAREESFGPIMIISKFY--DIDEVIVRANKTEYGLASGVFTNDISKALRVADAIDAGTVFINTYNKTDVAAPFGGFKQSGFGKDLGQEALNEYLKTKTVTVEY 3011
A EA G VFK+ +WRV Q + EV +Y++ ELNVL FC+QFIPMEVI+ PKH SIIYHPSLLP+HRGASAINWTLI+GD KGG T+FWADDGLDTGP+LLQRECDV NDTV+++Y RF+ PEG+K VEAVR I G+AP I Q +Y+ + KK ++I+WNQS ++HN+IRG+DKVPGAW+ ++GQKVTFYGS L + V +G L I G P ++ GL++ G+D + + ++FED GK + AS+Y T+ L+E+E+A + +W+SIL IE +DFFK G SMDV R++E++K + +L+ + IY+ +TF + V + RG +++L D V N N MT +PHQ+FIN EFV++E GK Y + NP D IC VS + DVD AV AAKEAFE EWGKM+ RDRGR+LYKLADLME+H EELAT+E++DSGAVYTLALKTH+GMSI+TFRYFAGWCDKIQGSTIPI+ ARPN+NL FTKKEPIGVC I+ PWNYPLMMLAWK AACLAAGNTVVLKPAQVTPL +LKF EL+ AG P GVIN+LPGSG++ G +S+HPD+RKLGFTGST IG+ IM SCA SNLKK SLELGGKSPLIIF+DCDMDKAV+ SSVFFNKGENCIAAGR+FV+ IHD F+K VVE+VKKMKIGDPLDRS DHGPQNH+ HL KL+EFC GVKEGA LV GG R G+F EPT+FT+V D MYIA+EESFGP+MIISKF +IDEV+ AN TEYGLASGVFT DISKAL V++ ++AGTVF+NTYNKTDVA PFGGFKQSGFGKDLGQEALNEYLKTK VT+EY
Sbjct: 43 ATEAEKDGVPVFKLSRWRVKGQALPEVVSQYKATGPELNVLPFCSQFIPMEVIDHPKHGSIIYHPSLLPRHRGASAINWTLIHGDKKGGFTVFWADDGLDTGPILLQRECDVEPNDTVNTIYKRFLFPEGVKGTVEAVRLIAEGKAPRIPQPEEGATYECIQKKENSKIDWNQSAEAIHNWIRGNDKVPGAWAEVDGQKVTFYGSTLIDNGVAANGRPLEICGARRPGMVTKAGLVLFGNDGGALLVKNMQFED-GKMIAASQYFSAGASATVV-LTEEEKAFAEQMRAVWQSILTNVGQIEDSTDFFKSGAASMDVVRLVEEVKLYASSCQLQNEDIYMNTTFQDFIQMCVRKLRGEDDEEELIVDYVEKNINNMTVKMPHQLFINGEFVDAEGGKTYKTINPCDGMAICDVSLAQISDVDKAVAAAKEAFEEQEWGKMNPRDRGRLLYKLADLMEQHQEELATIEAIDSGAVYTLALKTHVGMSIQTFRYFAGWCDKIQGSTIPINQARPNRNLCFTKKEPIGVCAIVIPWNYPLMMLAWKTAACLAAGNTVVLKPAQVTPLTALKFAELASRAGLPKGVINILPGSGSLVGQRLSDHPDVRKLGFTGSTEIGKQIMKSCAVSNLKKVSLELGGKSPLIIFADCDMDKAVRMGMSSVFFNKGENCIAAGRLFVEESIHDQFVKKVVEEVKKMKIGDPLDRSTDHGPQNHKAHLDKLVEFCQFGVKEGAVLVCGGHALQRPGFFFEPTVFTNVQDHMYIAKEESFGPVMIISKFKSGEIDEVLRSANATEYGLASGVFTRDISKALYVSERLNAGTVFVNTYNKTDVATPFGGFKQSGFGKDLGQEALNEYLKTKAVTIEY 902 HSP 2 Score: 74.7146 bits (182), Expect = 3.838e-13 Identity = 33/68 (48.53%), Postives = 49/68 (72.06%), Query Frame = 1
Query: 115 MKIAIIGQSIFGAQVYKELKNEGHDIVGVFTIPDRNGRSDPLGIFYWE*GFTTLLMTSKKSQGRPLAQ 318
MKIA+IGQS+FG +VYKEL+ +GH IVGVFTIPD++G++DPL + G ++ + +G+ L +
Sbjct: 1 MKIAVIGQSVFGKEVYKELRKDGHTIVGVFTIPDKDGKADPLATEAEKDGVPVFKLSRWRVKGQALPE 68
BLAST of 10-formyltetrahydrofolate dehydrogenase vs. Ensembl Medaka
Match: aldh1l2 (aldehyde dehydrogenase 1 family member L2 [Source:NCBI gene;Acc:101167504]) HSP 1 Score: 1082.4 bits (2798), Expect = 0.000e+0 Identity = 538/902 (59.65%), Postives = 672/902 (74.50%), Query Frame = 3
Query: 438 AMEAIDLGTKVFKIPKWRVNNQIIKEVFEEYRSINAELNVLAFCTQFIPMEVINAPKHRSIIYHPSLLPKHRGASAINWTLINGDLKGGLTIFWADDGLDTGPVLLQRECDVHINDTVDSLYSRFMMPEGIKAMVEAVRQIESGRAPAIAQYHPDHSYDQMVKKSTAEINWNQSGLSLHNFIRGHDKVPGAWSWINGQKVTFYGSQLWYHDVVHDGPSLAIQGLSDPAVLHNHGLLIRGSDNQWINIAQLKFEDTGKTVQASKYGKGDEITTMADLSEDERAMEIPLMKIWKSILMG-SDIEPESDFFKLGGTSMDVTRIIEQIKCNF-NVELKIDHIYLYSTFDTLFKWIVLRKRGGGSQKKLHYDAVIINANKMTFPIPHQIFINNEFVNSESGKEYDSKNPSDESVICRVSYSSXXXXXXXXXXXXXXFEFGEWGKMSARDRGRILYKL----------------------------------------ADLMEEHAEELATLESLDSGAVYTLALKTHIGMSIETFRYFAGWCDKIQGSTIPISNARPNKNLSFTKKEPIGVCGIITPWNYPLMMLAWKVAACLAAGNTVVLKPAQVTPLASLKFCELSVEAGFPPGVINVLPGSGAIAGTAISEHPDIRKLGFTGSTAIGQTIMSSCAKSNLKKCSLELGGKSPLIIFSDCDMDKAVKSACSSVFFNKGENCIAAGRIFVDVRIHDVFLKLVVEDVKKMKIGDPLDRSVDHGPQNHEIHLLKLLEFCDIGVKEGAKLVFGGKRCDRKGYFMEPTIFTSVTDDMYIAREESFGPIMIISKFY--DIDEVIVRANKTEYGLASGVFTNDISKALRVADAIDAGTVFINTYNKTDVAAPFGGFKQSGFGKDLGQEALNEYLKTKTVTVEY 3011
A+ A GT +FK P+WR Q + EV + Y+S+ AELNV+ FC+QFIPM VI+ PKH SIIYHPS+LP HRGASAINWTLI+GD K G T+FWADDGLDTGP+LLQREC V +DTVD+LY+RF+ PEGIKAMVE+V+ I G+AP I Q SY+ + +KS A ++ Q ++HN+IRGHDKVPGAW+ I GQ VTFYGS + V P L I+G S P ++ +GL++ G+D + + + L+FED GK + ASKY E +++ +L+ +E+ M + IWK+IL I +DFFK G SMDV R++E++K V+L+ + +Y+ +TF + V + RG +++L D N MT +P+Q FIN +F ++E GK Y + NP+D SVIC+VSY++ DVD AV AAKEAF+ G WG+M+ RDRG +LYKL ADLMEEH EELAT+ES+DSGAVYTLALKTH+GMSI+TFRYFAGWCDKIQG TIPI+ ARPN+NL+FTKKEP+GVC I+ PWNYPLMMLAWK AACLAAGNT+VLKPAQVTPL +LKF ELSV+AG P GVIN+LPGSG + G +S+HPDIRKLGFTGST +G+ IM SCA SNLKK SLELGGKSPLIIFSDCDMDKAV+ SSVFFNKGENCIAAGR+FV+ IHD +++ VVE++ KMKIGDPLDRS DHGPQNH+ HL KLLE+C+IGVKEGA LV+GGK+ DR G+FM+PT+FT V D M+IA+EESFGP+M++SKF D+D V+ RAN TEYGLASGVFT DI+KA+ V++ ++AGTVF+NTYNKTDVA+PFGGFKQSGFGKDLG++AL+EYLKTK VTVEY
Sbjct: 90 AVAAEKDGTPLFKFPRWRNKGQPLPEVVDAYKSVGAELNVMPFCSQFIPMNVIDHPKHGSIIYHPSILPLHRGASAINWTLIHGDEKAGFTVFWADDGLDTGPILLQRECAVEPDDTVDTLYNRFLFPEGIKAMVESVQLIADGKAPRIPQPEEGASYEGIQRKSNARVDLAQPAKAIHNWIRGHDKVPGAWALIGGQSVTFYGSSMLSGSVPAGQP-LEIEGASQPGIISKNGLVLFGNDGKALLVKNLQFED-GKMIPASKYFSSGENSSV-ELTNEEKQMAEEIRNIWKAILSNVPAIVDTTDFFKSGAASMDVVRLVEEVKQKCAGVQLQNEDVYMATTFQDFIQIFVRKLRGEDQEEELTIDYATKEVNNMTVKMPYQCFINGKFEDAEDGKTYSTINPTDGSVICKVSYAAVGDVDRAVAAAKEAFDNGPWGRMNPRDRGSLLYKLKAAPGKPAFIDCTRVSAGRSKSLHRSAFQKKKNCSLAGMLADLMEEHQEELATIESIDSGAVYTLALKTHVGMSIQTFRYFAGWCDKIQGKTIPINQARPNRNLTFTKKEPLGVCAIVIPWNYPLMMLAWKSAACLAAGNTLVLKPAQVTPLTALKFAELSVKAGIPKGVINILPGSGGMVGQRLSDHPDIRKLGFTGSTPVGKQIMKSCALSNLKKVSLELGGKSPLIIFSDCDMDKAVRMGMSSVFFNKGENCIAAGRLFVEESIHDEYIRRVVEEIMKMKIGDPLDRSTDHGPQNHKAHLDKLLEYCEIGVKEGATLVYGGKQVDRPGFFMQPTVFTDVEDHMFIAKEESFGPVMVVSKFRNGDVDGVLQRANDTEYGLASGVFTRDINKAMYVSEQLEAGTVFVNTYNKTDVASPFGGFKQSGFGKDLGEDALSEYLKTKAVTVEY 988 HSP 2 Score: 75.8702 bits (185), Expect = 2.195e-13 Identity = 30/74 (40.54%), Postives = 51/74 (68.92%), Query Frame = 1
Query: 97 HNFNPRMKIAIIGQSIFGAQVYKELKNEGHDIVGVFTIPDRNGRSDPLGIFYWE*GFTTLLMTSKKSQGRPLAQ 318
H + ++K+AIIGQS+FG +VY L+ +GH +VGVFT+PD++G++DPL + + G +++G+PL +
Sbjct: 42 HYYQKKLKLAIIGQSLFGQEVYSSLRKQGHKVVGVFTVPDKDGKADPLAVAAEKDGTPLFKFPRWRNKGQPLPE 115
BLAST of 10-formyltetrahydrofolate dehydrogenase vs. Ensembl Medaka
Match: aldh1l2 (aldehyde dehydrogenase 1 family member L2 [Source:NCBI gene;Acc:101167504]) HSP 1 Score: 1081.63 bits (2796), Expect = 0.000e+0 Identity = 538/902 (59.65%), Postives = 672/902 (74.50%), Query Frame = 3
Query: 438 AMEAIDLGTKVFKIPKWRVNNQIIKEVFEEYRSINAELNVLAFCTQFIPMEVINAPKHRSIIYHPSLLPKHRGASAINWTLINGDLKGGLTIFWADDGLDTGPVLLQRECDVHINDTVDSLYSRFMMPEGIKAMVEAVRQIESGRAPAIAQYHPDHSYDQMVKKSTAEINWNQSGLSLHNFIRGHDKVPGAWSWINGQKVTFYGSQLWYHDVVHDGPSLAIQGLSDPAVLHNHGLLIRGSDNQWINIAQLKFEDTGKTVQASKYGKGDEITTMADLSEDERAMEIPLMKIWKSILMG-SDIEPESDFFKLGGTSMDVTRIIEQIKCNF-NVELKIDHIYLYSTFDTLFKWIVLRKRGGGSQKKLHYDAVIINANKMTFPIPHQIFINNEFVNSESGKEYDSKNPSDESVICRVSYSSXXXXXXXXXXXXXXFEFGEWGKMSARDRGRILYKL----------------------------------------ADLMEEHAEELATLESLDSGAVYTLALKTHIGMSIETFRYFAGWCDKIQGSTIPISNARPNKNLSFTKKEPIGVCGIITPWNYPLMMLAWKVAACLAAGNTVVLKPAQVTPLASLKFCELSVEAGFPPGVINVLPGSGAIAGTAISEHPDIRKLGFTGSTAIGQTIMSSCAKSNLKKCSLELGGKSPLIIFSDCDMDKAVKSACSSVFFNKGENCIAAGRIFVDVRIHDVFLKLVVEDVKKMKIGDPLDRSVDHGPQNHEIHLLKLLEFCDIGVKEGAKLVFGGKRCDRKGYFMEPTIFTSVTDDMYIAREESFGPIMIISKFY--DIDEVIVRANKTEYGLASGVFTNDISKALRVADAIDAGTVFINTYNKTDVAAPFGGFKQSGFGKDLGQEALNEYLKTKTVTVEY 3011
A+ A GT +FK P+WR Q + EV + Y+S+ AELNV+ FC+QFIPM VI+ PKH SIIYHPS+LP HRGASAINWTLI+GD K G T+FWADDGLDTGP+LLQREC V +DTVD+LY+RF+ PEGIKAMVE+V+ I G+AP I Q SY+ + +KS A ++ Q ++HN+IRGHDKVPGAW+ I GQ VTFYGS + V P L I+G S P ++ +GL++ G+D + + + L+FED GK + ASKY E +++ +L+ +E+ M + IWK+IL I +DFFK G SMDV R++E++K V+L+ + +Y+ +TF + V + RG +++L D N MT +P+Q FIN +F ++E GK Y + NP+D SVIC+VSY++ DVD AV AAKEAF+ G WG+M+ RDRG +LYKL ADLMEEH EELAT+ES+DSGAVYTLALKTH+GMSI+TFRYFAGWCDKIQG TIPI+ ARPN+NL+FTKKEP+GVC I+ PWNYPLMMLAWK AACLAAGNT+VLKPAQVTPL +LKF ELSV+AG P GVIN+LPGSG + G +S+HPDIRKLGFTGST +G+ IM SCA SNLKK SLELGGKSPLIIFSDCDMDKAV+ SSVFFNKGENCIAAGR+FV+ IHD +++ VVE++ KMKIGDPLDRS DHGPQNH+ HL KLLE+C+IGVKEGA LV+GGK+ DR G+FM+PT+FT V D M+IA+EESFGP+M++SKF D+D V+ RAN TEYGLASGVFT DI+KA+ V++ ++AGTVF+NTYNKTDVA+PFGGFKQSGFGKDLG++AL+EYLKTK VTVEY
Sbjct: 65 AVAAEKDGTPLFKFPRWRNKGQPLPEVVDAYKSVGAELNVMPFCSQFIPMNVIDHPKHGSIIYHPSILPLHRGASAINWTLIHGDEKAGFTVFWADDGLDTGPILLQRECAVEPDDTVDTLYNRFLFPEGIKAMVESVQLIADGKAPRIPQPEEGASYEGIQRKSNARVDLAQPAKAIHNWIRGHDKVPGAWALIGGQSVTFYGSSMLSGSVPAGQP-LEIEGASQPGIISKNGLVLFGNDGKALLVKNLQFED-GKMIPASKYFSSGENSSV-ELTNEEKQMAEEIRNIWKAILSNVPAIVDTTDFFKSGAASMDVVRLVEEVKQKCAGVQLQNEDVYMATTFQDFIQIFVRKLRGEDQEEELTIDYATKEVNNMTVKMPYQCFINGKFEDAEDGKTYSTINPTDGSVICKVSYAAVGDVDRAVAAAKEAFDNGPWGRMNPRDRGSLLYKLKAAPGKPAFIDCTRVSAGRSKSLHRSAFQKKKNCSLAGMLADLMEEHQEELATIESIDSGAVYTLALKTHVGMSIQTFRYFAGWCDKIQGKTIPINQARPNRNLTFTKKEPLGVCAIVIPWNYPLMMLAWKSAACLAAGNTLVLKPAQVTPLTALKFAELSVKAGIPKGVINILPGSGGMVGQRLSDHPDIRKLGFTGSTPVGKQIMKSCALSNLKKVSLELGGKSPLIIFSDCDMDKAVRMGMSSVFFNKGENCIAAGRLFVEESIHDEYIRRVVEEIMKMKIGDPLDRSTDHGPQNHKAHLDKLLEYCEIGVKEGATLVYGGKQVDRPGFFMQPTVFTDVEDHMFIAKEESFGPVMVVSKFRNGDVDGVLQRANDTEYGLASGVFTRDINKAMYVSEQLEAGTVFVNTYNKTDVASPFGGFKQSGFGKDLGEDALSEYLKTKAVTVEY 963 HSP 2 Score: 75.8702 bits (185), Expect = 2.168e-13 Identity = 30/74 (40.54%), Postives = 51/74 (68.92%), Query Frame = 1
Query: 97 HNFNPRMKIAIIGQSIFGAQVYKELKNEGHDIVGVFTIPDRNGRSDPLGIFYWE*GFTTLLMTSKKSQGRPLAQ 318
H + ++K+AIIGQS+FG +VY L+ +GH +VGVFT+PD++G++DPL + + G +++G+PL +
Sbjct: 17 HYYQKKLKLAIIGQSLFGQEVYSSLRKQGHKVVGVFTVPDKDGKADPLAVAAEKDGTPLFKFPRWRNKGQPLPE 90
BLAST of 10-formyltetrahydrofolate dehydrogenase vs. Ensembl Medaka
Match: aldh1l2 (aldehyde dehydrogenase 1 family member L2 [Source:NCBI gene;Acc:101167504]) HSP 1 Score: 1008.44 bits (2606), Expect = 0.000e+0 Identity = 510/863 (59.10%), Postives = 636/863 (73.70%), Query Frame = 3
Query: 438 AMEAIDLGTKVFKIPKWRVNNQIIKEVFEEYRSINAELNVLAFCTQFIPMEVINAPKHRSIIYHPSLLPKHRGASAINWTLINGDLKGGLTIFWADDGLDTGPVLLQRECDVHINDTVDSLYSRFMMPEGIKAMVEAVRQIESGRAPAIAQYHPDHSYDQMVKKSTAEINWNQSGLSLHNFIRGHDKVPGAWSWINGQKVTFYGSQLWYHDVVHDGPSLAIQGLSDPAVLHNHGLLIRGSDNQWINIAQLKFEDTGKTVQASKYGKGDEITTMADLSEDERAMEIPLMKIWKSILMG-SDIEPESDFFKLGGTSMDVTRIIEQIK--CNFNVELKIDHIYLYSTFDTLFKWIVLRKRGGGSQKKLHYDAVIINANKMTFPIPHQIFINNEFVNSESGKEYDSKNPSDESVICRVSYSSXXXXXXXXXXXXXXFEFGEWGKMSARDRGRILYKLADLMEEHAEELATLESLDSGAVYTLALKTHIGMSIETFRYFAGWCDKIQGSTIPISNARPNKNLSFTKKEPIGVCGIITPWNYPLMMLAWKVAACLAAGNTVVLKPAQVTPLASLKFCELSVEAGFPPGVINVLPGSGAIAGTAISEHPDIRKLGFTGSTAIGQTIMSSCAKSNLKKCSLELGGKSPLIIFSDCDMDKAVKSACSSVFFNKGENCIAAGRIFVDVRIHDVFLKLVVEDVKKMKIGDPLDRSVDHGPQNHEIHLLKLLEFCDIGVKEGAKLVFGGKRCDRKGYFMEPTIFTSVTDDMYIAREESFGPIMIISKFY--DIDEVIVRANKTEYGLASGVFTNDISKALRVADAIDAGTVFINTYNKTDVAAPFGGFKQSGFGKDLGQEALNEYLKTKTVTVEY 3011
A+ A GT +FK P+WR Q + EV + Y+S+ AELNV+ FC+QFIPM VI+ PKH SIIYHPS+LP HRGASAINWTLI+GD K G T+FWADDGLDTGP+LLQREC V +DTVD+LY+RF+ PEGIKAMV+ Q ++HN+IRGHDKVPGAW+ I GQ VTFYGS + V P L I+G S P ++ +GL++ G+D + + + L+FED GK + ASKY E +++ +L+ +E+ M + IWK+IL I +DFFK G SMDV R++E++K C V+L+ + +Y+ +TF + V + RG +++L D V +N MT +P+Q FIN +F ++E GK Y + NP+D SVIC+VSY++ DVD AV AAKEAF+ G WG+M+ RDRG +LYKLADLMEEH EELAT+ES+DSGAVYTLALKTH+GMSI+TFRYFAGWCDKIQ P + + VC I+ PWNYPLMMLAWK AACLAAGNT+VLKPAQVTPL +LKF ELSV+AG P GVIN+LPGSG + G +S+HPDIRKLGFTGST +G+ IM SCA SNLKK SLELGGKSPLIIFSDCDMDKAV+ SSVFFNKGENCIAAGR+FV+ IHD +++ VVE++ KMKIGDPLDRS DHGPQNH+ HL KLLE+C+IGVKEGA LV+GGK+ DR G+FM+PT+FT V D M+IA+EESFGP+M++SKF D+D V+ RAN TEYGLASGVFT DI+KA+ V++ ++AGTVF+NTYNKTDVA+PFGGFKQSGFGKDLG++AL+EYLKTK VTVEY
Sbjct: 43 AVAAEKDGTPLFKFPRWRNKGQPLPEVVDAYKSVGAELNVMPFCSQFIPMNVIDHPKHGSIIYHPSILPLHRGASAINWTLIHGDEKAGFTVFWADDGLDTGPILLQRECAVEPDDTVDTLYNRFLFPEGIKAMVDLA----------------------------------QPAKAIHNWIRGHDKVPGAWALIGGQSVTFYGSSMLSGSVPAGQP-LEIEGASQPGIISKNGLVLFGNDGKALLVKNLQFED-GKMIPASKYFSSGENSSV-ELTNEEKQMAEEIRNIWKAILSNVPAIVDTTDFFKSGAASMDVVRLVEEVKQKCA-GVQLQNEDVYMATTFQDFIQIFVRKLRGEDQEEELTIDYVKVN--NMTVKMPYQCFINGKFEDAEDGKTYSTINPTDGSVICKVSYAAVGDVDRAVAAAKEAFDNGPWGRMNPRDRGSLLYKLADLMEEHQEELATIESIDSGAVYTLALKTHVGMSIQTFRYFAGWCDKIQVGAKPFPSTK--------------VCAIVIPWNYPLMMLAWKSAACLAAGNTLVLKPAQVTPLTALKFAELSVKAGIPKGVINILPGSGGMVGQRLSDHPDIRKLGFTGSTPVGKQIMKSCALSNLKKVSLELGGKSPLIIFSDCDMDKAVRMGMSSVFFNKGENCIAAGRLFVEESIHDEYIRRVVEEIMKMKIGDPLDRSTDHGPQNHKAHLDKLLEYCEIGVKEGATLVYGGKQVDRPGFFMQPTVFTDVEDHMFIAKEESFGPVMVVSKFRNGDVDGVLQRANDTEYGLASGVFTRDINKAMYVSEQLEAGTVFVNTYNKTDVASPFGGFKQSGFGKDLGEDALSEYLKTKAVTVEY 851 HSP 2 Score: 69.707 bits (169), Expect = 1.564e-11 Identity = 29/68 (42.65%), Postives = 48/68 (70.59%), Query Frame = 1
Query: 115 MKIAIIGQSIFGAQVYKELKNEGHDIVGVFTIPDRNGRSDPLGIFYWE*GFTTLLMTSKKSQGRPLAQ 318
+K+AIIGQS+FG +VY L+ +GH +VGVFT+PD++G++DPL + + G +++G+PL +
Sbjct: 1 LKLAIIGQSLFGQEVYSSLRKQGHKVVGVFTVPDKDGKADPLAVAAEKDGTPLFKFPRWRNKGQPLPE 68
BLAST of 10-formyltetrahydrofolate dehydrogenase vs. Planmine SMEST
Match: SMESG000005275.1 (SMESG000005275.1) HSP 1 Score: 1667.13 bits (4316), Expect = 0.000e+0 Identity = 828/858 (96.50%), Postives = 833/858 (97.09%), Query Frame = 3
Query: 438 AMEAIDLGTKVFKIPKWRVNNQIIKEVFEEYRSINAELNVLAFCTQFIPMEVINAPKHRSIIYHPSLLPKHRGASAINWTLINGDLKGGLTIFWADDGLDTGPVLLQRECDVHINDTVDSLYSRFMMPEGIKAMVEAVRQIESGRAPAIAQYHPDHSYDQMVKKSTAEINWNQSGLSLHNFIRGHDKVPGAWSWINGQKVTFYGSQLWYHDVVHDGPSLAIQGLSDPAVLHNHGLLIRGSDNQWINIAQLKFEDTGKTVQASKYGKGDEITTMADLSEDERAMEIPLMKIWKSILMGSDIEPESDFFKLGGTSMDVTRIIEQIKCNFNVELKIDHIYLYSTFDTLFKWIVLRKRGGGSQKKLHYDAVIINANKMTFPIPHQIFINNEFVNSESGKEYDSKNPSDESVICRVSYSSXXXXXXXXXXXXXXFEFGEWGKMSARDRGRILYKLADLMEEHAEELATLESLDSGAVYTLALKTHIGMSIETFRYFAGWCDKIQGSTIPISNARPNKNLSFTKKEPIGVCGIITPWNYPLMMLAWKVAACLAAGNTVVLKPAQVTPLASLKFCELSVEAGFPPGVINVLPGSGAIAGTAISEHPDIRKLGFTGSTAIGQTIMSSCAKSNLKKCSLELGGKSPLIIFSDCDMDKAVKSACSSVFFNKGENCIAAGRIFVDVRIHDVFLKLVVEDVKKMKIGDPLDRSVDHGPQNHEIHLLKLLEFCDIGVKEGAKLVFGGKRCDRKGYFMEPTIFTSVTDDMYIAREESFGPIMIISKFYDIDEVIVRANKTEYGLASGVFTNDISKALRVADAIDAGTVFINTYNKTDVAAPFGGFKQSGFGKDLGQEALNEYLKTKTVTVEY 3011
AMEAIDLGTKVFKIPKWRVNNQ+IKEVFEEYRSINAELNVLAFCTQFIPMEVINAPKHRSIIYHPSLLPKHRGASAINWTLINGDLKGGLTIFWADDGLDTGPVLLQRECDVHINDTVDSLYSRFMMPEGIKAMVEAVRQIESGRAPAIAQYHPDHSYDQMVKKSTAEINWNQSGLSLHNFIRGHDKV + + +K F PS +IQGLSDPAVLHNHGLLIRGSDNQWINIAQLKFEDTGKTVQASKYGKGDEITTMADLSEDERAMEIPLMKIWKSILMGSDIEPESDFFKLGGTSMDVTRIIEQIKCNFNVELKIDHIYLYSTFDTLFKWIVLRKRGGGSQKKLHYDAVIINANKMTFPIPHQIFINNEFVNSESGKEYDSKNPSDESVICRVSYSSKKDVDIAVKAAKEAFEFGEWGKMSARDRGRILYKLADLMEEHAEELATLESLDSGAVYTLALKTHIGMSIETFRYFAGWCDKIQGSTIPISNARPNKNLSFTKKEPIGVCGIITPWNYPLMMLAWKVAACLAAGNTVVLKPAQVTPLASLKFCELSVEAGFP GVINVLPGSGAIAGTAISEHPDIRKLGFTGSTAIGQTIMSSCAKSNLKKCSLELGGKSPLIIFSDCDMDKAVKSACSSVFFNKGENCIAAGRIFVDVRIHDVFLKLVVEDVKKMKIGDPLDRSVDHGPQNHEIHLLKLLEFCDIGVKEGAKLVFGGKRCDRKGYFMEPTIFTSVTDDMYIAREESFGPIMIISKFYDIDEVIVRANKTEYGLASGVFTNDISKALRVADAIDAGTVFINTYNKTDVAAPFGGFKQSGFGKDLGQEALNEYLKTKTVTVEY
Sbjct: 69 AMEAIDLGTKVFKIPKWRVNNQMIKEVFEEYRSINAELNVLAFCTQFIPMEVINAPKHRSIIYHPSLLPKHRGASAINWTLINGDLKGGLTIFWADDGLDTGPVLLQRECDVHINDTVDSLYSRFMMPEGIKAMVEAVRQIESGRAPAIAQYHPDHSYDQMVKKSTAEINWNQSGLSLHNFIRGHDKVRVPGAGLMARKSHFMA------------PS-SIQGLSDPAVLHNHGLLIRGSDNQWINIAQLKFEDTGKTVQASKYGKGDEITTMADLSEDERAMEIPLMKIWKSILMGSDIEPESDFFKLGGTSMDVTRIIEQIKCNFNVELKIDHIYLYSTFDTLFKWIVLRKRGGGSQKKLHYDAVIINANKMTFPIPHQIFINNEFVNSESGKEYDSKNPSDESVICRVSYSSKKDVDIAVKAAKEAFEFGEWGKMSARDRGRILYKLADLMEEHAEELATLESLDSGAVYTLALKTHIGMSIETFRYFAGWCDKIQGSTIPISNARPNKNLSFTKKEPIGVCGIITPWNYPLMMLAWKVAACLAAGNTVVLKPAQVTPLASLKFCELSVEAGFPSGVINVLPGSGAIAGTAISEHPDIRKLGFTGSTAIGQTIMSSCAKSNLKKCSLELGGKSPLIIFSDCDMDKAVKSACSSVFFNKGENCIAAGRIFVDVRIHDVFLKLVVEDVKKMKIGDPLDRSVDHGPQNHEIHLLKLLEFCDIGVKEGAKLVFGGKRCDRKGYFMEPTIFTSVTDDMYIAREESFGPIMIISKFYDIDEVIVRANKTEYGLASGVFTNDISKALRVADAIDAGTVFINTYNKTDVAAPFGGFKQSGFGKDLGQEALNEYLKTKTVTVEY 913 HSP 2 Score: 151.754 bits (382), Expect = 5.097e-37 Identity = 68/70 (97.14%), Postives = 69/70 (98.57%), Query Frame = 1
Query: 37 MILYKFLKSYNLKLFQHLHFHNFNPRMKIAIIGQSIFGAQVYKELKNEGHDIVGVFTIPDRNGRSDPLGI 246
MILYKFLKSYNLKLFQHLHFHNFNPRMKIAIIGQSIFGAQVYKELKNEGHDIVGVFTIPDRNGRSDPL +
Sbjct: 1 MILYKFLKSYNLKLFQHLHFHNFNPRMKIAIIGQSIFGAQVYKELKNEGHDIVGVFTIPDRNGRSDPLAM 70
BLAST of 10-formyltetrahydrofolate dehydrogenase vs. Planmine SMEST
Match: SMESG000005275.1 (SMESG000005275.1) HSP 1 Score: 1666.74 bits (4315), Expect = 0.000e+0 Identity = 828/858 (96.50%), Postives = 833/858 (97.09%), Query Frame = 3
Query: 438 AMEAIDLGTKVFKIPKWRVNNQIIKEVFEEYRSINAELNVLAFCTQFIPMEVINAPKHRSIIYHPSLLPKHRGASAINWTLINGDLKGGLTIFWADDGLDTGPVLLQRECDVHINDTVDSLYSRFMMPEGIKAMVEAVRQIESGRAPAIAQYHPDHSYDQMVKKSTAEINWNQSGLSLHNFIRGHDKVPGAWSWINGQKVTFYGSQLWYHDVVHDGPSLAIQGLSDPAVLHNHGLLIRGSDNQWINIAQLKFEDTGKTVQASKYGKGDEITTMADLSEDERAMEIPLMKIWKSILMGSDIEPESDFFKLGGTSMDVTRIIEQIKCNFNVELKIDHIYLYSTFDTLFKWIVLRKRGGGSQKKLHYDAVIINANKMTFPIPHQIFINNEFVNSESGKEYDSKNPSDESVICRVSYSSXXXXXXXXXXXXXXFEFGEWGKMSARDRGRILYKLADLMEEHAEELATLESLDSGAVYTLALKTHIGMSIETFRYFAGWCDKIQGSTIPISNARPNKNLSFTKKEPIGVCGIITPWNYPLMMLAWKVAACLAAGNTVVLKPAQVTPLASLKFCELSVEAGFPPGVINVLPGSGAIAGTAISEHPDIRKLGFTGSTAIGQTIMSSCAKSNLKKCSLELGGKSPLIIFSDCDMDKAVKSACSSVFFNKGENCIAAGRIFVDVRIHDVFLKLVVEDVKKMKIGDPLDRSVDHGPQNHEIHLLKLLEFCDIGVKEGAKLVFGGKRCDRKGYFMEPTIFTSVTDDMYIAREESFGPIMIISKFYDIDEVIVRANKTEYGLASGVFTNDISKALRVADAIDAGTVFINTYNKTDVAAPFGGFKQSGFGKDLGQEALNEYLKTKTVTVEY 3011
AMEAIDLGTKVFKIPKWRVNNQ+IKEVFEEYRSINAELNVLAFCTQFIPMEVINAPKHRSIIYHPSLLPKHRGASAINWTLINGDLKGGLTIFWADDGLDTGPVLLQRECDVHINDTVDSLYSRFMMPEGIKAMVEAVRQIESGRAPAIAQYHPDHSYDQMVKKSTAEINWNQSGLSLHNFIRGHDKV + + +K F PS +IQGLSDPAVLHNHGLLIRGSDNQWINIAQLKFEDTGKTVQASKYGKGDEITTMADLSEDERAMEIPLMKIWKSILMGSDIEPESDFFKLGGTSMDVTRIIEQIKCNFNVELKIDHIYLYSTFDTLFKWIVLRKRGGGSQKKLHYDAVIINANKMTFPIPHQIFINNEFVNSESGKEYDSKNPSDESVICRVSYSSKKDVDIAVKAAKEAFEFGEWGKMSARDRGRILYKLADLMEEHAEELATLESLDSGAVYTLALKTHIGMSIETFRYFAGWCDKIQGSTIPISNARPNKNLSFTKKEPIGVCGIITPWNYPLMMLAWKVAACLAAGNTVVLKPAQVTPLASLKFCELSVEAGFP GVINVLPGSGAIAGTAISEHPDIRKLGFTGSTAIGQTIMSSCAKSNLKKCSLELGGKSPLIIFSDCDMDKAVKSACSSVFFNKGENCIAAGRIFVDVRIHDVFLKLVVEDVKKMKIGDPLDRSVDHGPQNHEIHLLKLLEFCDIGVKEGAKLVFGGKRCDRKGYFMEPTIFTSVTDDMYIAREESFGPIMIISKFYDIDEVIVRANKTEYGLASGVFTNDISKALRVADAIDAGTVFINTYNKTDVAAPFGGFKQSGFGKDLGQEALNEYLKTKTVTVEY
Sbjct: 43 AMEAIDLGTKVFKIPKWRVNNQMIKEVFEEYRSINAELNVLAFCTQFIPMEVINAPKHRSIIYHPSLLPKHRGASAINWTLINGDLKGGLTIFWADDGLDTGPVLLQRECDVHINDTVDSLYSRFMMPEGIKAMVEAVRQIESGRAPAIAQYHPDHSYDQMVKKSTAEINWNQSGLSLHNFIRGHDKVRVPGAGLMARKSHFMA------------PS-SIQGLSDPAVLHNHGLLIRGSDNQWINIAQLKFEDTGKTVQASKYGKGDEITTMADLSEDERAMEIPLMKIWKSILMGSDIEPESDFFKLGGTSMDVTRIIEQIKCNFNVELKIDHIYLYSTFDTLFKWIVLRKRGGGSQKKLHYDAVIINANKMTFPIPHQIFINNEFVNSESGKEYDSKNPSDESVICRVSYSSKKDVDIAVKAAKEAFEFGEWGKMSARDRGRILYKLADLMEEHAEELATLESLDSGAVYTLALKTHIGMSIETFRYFAGWCDKIQGSTIPISNARPNKNLSFTKKEPIGVCGIITPWNYPLMMLAWKVAACLAAGNTVVLKPAQVTPLASLKFCELSVEAGFPSGVINVLPGSGAIAGTAISEHPDIRKLGFTGSTAIGQTIMSSCAKSNLKKCSLELGGKSPLIIFSDCDMDKAVKSACSSVFFNKGENCIAAGRIFVDVRIHDVFLKLVVEDVKKMKIGDPLDRSVDHGPQNHEIHLLKLLEFCDIGVKEGAKLVFGGKRCDRKGYFMEPTIFTSVTDDMYIAREESFGPIMIISKFYDIDEVIVRANKTEYGLASGVFTNDISKALRVADAIDAGTVFINTYNKTDVAAPFGGFKQSGFGKDLGQEALNEYLKTKTVTVEY 887 HSP 2 Score: 93.5893 bits (231), Expect = 4.414e-19 Identity = 42/44 (95.45%), Postives = 43/44 (97.73%), Query Frame = 1
Query: 115 MKIAIIGQSIFGAQVYKELKNEGHDIVGVFTIPDRNGRSDPLGI 246
MKIAIIGQSIFGAQVYKELKNEGHDIVGVFTIPDRNGRSDPL +
Sbjct: 1 MKIAIIGQSIFGAQVYKELKNEGHDIVGVFTIPDRNGRSDPLAM 44
BLAST of 10-formyltetrahydrofolate dehydrogenase vs. Planmine SMEST
Match: SMESG000005275.1 (SMESG000005275.1) HSP 1 Score: 1428.69 bits (3697), Expect = 0.000e+0 Identity = 711/741 (95.95%), Postives = 716/741 (96.63%), Query Frame = 3
Query: 438 AMEAIDLGTKVFKIPKWRVNNQIIKEVFEEYRSINAELNVLAFCTQFIPMEVINAPKHRSIIYHPSLLPKHRGASAINWTLINGDLKGGLTIFWADDGLDTGPVLLQRECDVHINDTVDSLYSRFMMPEGIKAMVEAVRQIESGRAPAIAQYHPDHSYDQMVKKSTAEINWNQSGLSLHNFIRGHDKVPGAWSWINGQKVTFYGSQLWYHDVVHDGPSLAIQGLSDPAVLHNHGLLIRGSDNQWINIAQLKFEDTGKTVQASKYGKGDEITTMADLSEDERAMEIPLMKIWKSILMGSDIEPESDFFKLGGTSMDVTRIIEQIKCNFNVELKIDHIYLYSTFDTLFKWIVLRKRGGGSQKKLHYDAVIINANKMTFPIPHQIFINNEFVNSESGKEYDSKNPSDESVICRVSYSSXXXXXXXXXXXXXXFEFGEWGKMSARDRGRILYKLADLMEEHAEELATLESLDSGAVYTLALKTHIGMSIETFRYFAGWCDKIQGSTIPISNARPNKNLSFTKKEPIGVCGIITPWNYPLMMLAWKVAACLAAGNTVVLKPAQVTPLASLKFCELSVEAGFPPGVINVLPGSGAIAGTAISEHPDIRKLGFTGSTAIGQTIMSSCAKSNLKKCSLELGGKSPLIIFSDCDMDKAVKSACSSVFFNKGENCIAAGRIFVDVRIHDVFLKLVVEDVKKMKIGDPLDRSVDHGPQNHEIHLLKLLEFCDIGVKEGAKLVFGGKRCDRKG 2660
AMEAIDLGTKVFKIPKWRVNNQ+IKEVFEEYRSINAELNVLAFCTQFIPMEVINAPKHRSIIYHPSLLPKHRGASAINWTLINGDLKGGLTIFWADDGLDTGPVLLQRECDVHINDTVDSLYSRFMMPEGIKAMVEAVRQIESGRAPAIAQYHPDHSYDQMVKKSTAEINWNQSGLSLHNFIRGHDKV + + +K F PS +IQGLSDPAVLHNHGLLIRGSDNQWINIAQLKFEDTGKTVQASKYGKGDEITTMADLSEDERAMEIPLMKIWKSILMGSDIEPESDFFKLGGTSMDVTRIIEQIKCNFNVELKIDHIYLYSTFDTLFKWIVLRKRGGGSQKKLHYDAVIINANKMTFPIPHQIFINNEFVNSESGKEYDSKNPSDESVICRVSYSSKKDVDIAVKAAKEAFEFGEWGKMSARDRGRILYKLADLMEEHAEELATLESLDSGAVYTLALKTHIGMSIETFRYFAGWCDKIQGSTIPISNARPNKNLSFTKKEPIGVCGIITPWNYPLMMLAWKVAACLAAGNTVVLKPAQVTPLASLKFCELSVEAGFP GVINVLPGSGAIAGTAISEHPDIRKLGFTGSTAIGQTIMSSCAKSNLKKCSLELGGKSPLIIFSDCDMDKAVKSACSSVFFNKGENCIAAGRIFVDVRIHDVFLKLVVEDVKKMKIGDPLDRSVDHGPQNHEIHLLKLLEFCDIGVKEGAKLVFGGKRCDRKG
Sbjct: 43 AMEAIDLGTKVFKIPKWRVNNQMIKEVFEEYRSINAELNVLAFCTQFIPMEVINAPKHRSIIYHPSLLPKHRGASAINWTLINGDLKGGLTIFWADDGLDTGPVLLQRECDVHINDTVDSLYSRFMMPEGIKAMVEAVRQIESGRAPAIAQYHPDHSYDQMVKKSTAEINWNQSGLSLHNFIRGHDKVRVPGAGLMARKSHFMA------------PS-SIQGLSDPAVLHNHGLLIRGSDNQWINIAQLKFEDTGKTVQASKYGKGDEITTMADLSEDERAMEIPLMKIWKSILMGSDIEPESDFFKLGGTSMDVTRIIEQIKCNFNVELKIDHIYLYSTFDTLFKWIVLRKRGGGSQKKLHYDAVIINANKMTFPIPHQIFINNEFVNSESGKEYDSKNPSDESVICRVSYSSKKDVDIAVKAAKEAFEFGEWGKMSARDRGRILYKLADLMEEHAEELATLESLDSGAVYTLALKTHIGMSIETFRYFAGWCDKIQGSTIPISNARPNKNLSFTKKEPIGVCGIITPWNYPLMMLAWKVAACLAAGNTVVLKPAQVTPLASLKFCELSVEAGFPSGVINVLPGSGAIAGTAISEHPDIRKLGFTGSTAIGQTIMSSCAKSNLKKCSLELGGKSPLIIFSDCDMDKAVKSACSSVFFNKGENCIAAGRIFVDVRIHDVFLKLVVEDVKKMKIGDPLDRSVDHGPQNHEIHLLKLLEFCDIGVKEGAKLVFGGKRCDRKG 770 HSP 2 Score: 91.2781 bits (225), Expect = 2.127e-18 Identity = 42/44 (95.45%), Postives = 43/44 (97.73%), Query Frame = 1
Query: 115 MKIAIIGQSIFGAQVYKELKNEGHDIVGVFTIPDRNGRSDPLGI 246
MKIAIIGQSIFGAQVYKELKNEGHDIVGVFTIPDRNGRSDPL +
Sbjct: 1 MKIAIIGQSIFGAQVYKELKNEGHDIVGVFTIPDRNGRSDPLAM 44
BLAST of 10-formyltetrahydrofolate dehydrogenase vs. Planmine SMEST
Match: SMESG000005275.1 (SMESG000005275.1) HSP 1 Score: 1426.38 bits (3691), Expect = 0.000e+0 Identity = 711/741 (95.95%), Postives = 716/741 (96.63%), Query Frame = 3
Query: 438 AMEAIDLGTKVFKIPKWRVNNQIIKEVFEEYRSINAELNVLAFCTQFIPMEVINAPKHRSIIYHPSLLPKHRGASAINWTLINGDLKGGLTIFWADDGLDTGPVLLQRECDVHINDTVDSLYSRFMMPEGIKAMVEAVRQIESGRAPAIAQYHPDHSYDQMVKKSTAEINWNQSGLSLHNFIRGHDKVPGAWSWINGQKVTFYGSQLWYHDVVHDGPSLAIQGLSDPAVLHNHGLLIRGSDNQWINIAQLKFEDTGKTVQASKYGKGDEITTMADLSEDERAMEIPLMKIWKSILMGSDIEPESDFFKLGGTSMDVTRIIEQIKCNFNVELKIDHIYLYSTFDTLFKWIVLRKRGGGSQKKLHYDAVIINANKMTFPIPHQIFINNEFVNSESGKEYDSKNPSDESVICRVSYSSXXXXXXXXXXXXXXFEFGEWGKMSARDRGRILYKLADLMEEHAEELATLESLDSGAVYTLALKTHIGMSIETFRYFAGWCDKIQGSTIPISNARPNKNLSFTKKEPIGVCGIITPWNYPLMMLAWKVAACLAAGNTVVLKPAQVTPLASLKFCELSVEAGFPPGVINVLPGSGAIAGTAISEHPDIRKLGFTGSTAIGQTIMSSCAKSNLKKCSLELGGKSPLIIFSDCDMDKAVKSACSSVFFNKGENCIAAGRIFVDVRIHDVFLKLVVEDVKKMKIGDPLDRSVDHGPQNHEIHLLKLLEFCDIGVKEGAKLVFGGKRCDRKG 2660
AMEAIDLGTKVFKIPKWRVNNQ+IKEVFEEYRSINAELNVLAFCTQFIPMEVINAPKHRSIIYHPSLLPKHRGASAINWTLINGDLKGGLTIFWADDGLDTGPVLLQRECDVHINDTVDSLYSRFMMPEGIKAMVEAVRQIESGRAPAIAQYHPDHSYDQMVKKSTAEINWNQSGLSLHNFIRGHDKV + + +K F PS +IQGLSDPAVLHNHGLLIRGSDNQWINIAQLKFEDTGKTVQASKYGKGDEITTMADLSEDERAMEIPLMKIWKSILMGSDIEPESDFFKLGGTSMDVTRIIEQIKCNFNVELKIDHIYLYSTFDTLFKWIVLRKRGGGSQKKLHYDAVIINANKMTFPIPHQIFINNEFVNSESGKEYDSKNPSDESVICRVSYSSKKDVDIAVKAAKEAFEFGEWGKMSARDRGRILYKLADLMEEHAEELATLESLDSGAVYTLALKTHIGMSIETFRYFAGWCDKIQGSTIPISNARPNKNLSFTKKEPIGVCGIITPWNYPLMMLAWKVAACLAAGNTVVLKPAQVTPLASLKFCELSVEAGFP GVINVLPGSGAIAGTAISEHPDIRKLGFTGSTAIGQTIMSSCAKSNLKKCSLELGGKSPLIIFSDCDMDKAVKSACSSVFFNKGENCIAAGRIFVDVRIHDVFLKLVVEDVKKMKIGDPLDRSVDHGPQNHEIHLLKLLEFCDIGVKEGAKLVFGGKRCDRKG
Sbjct: 69 AMEAIDLGTKVFKIPKWRVNNQMIKEVFEEYRSINAELNVLAFCTQFIPMEVINAPKHRSIIYHPSLLPKHRGASAINWTLINGDLKGGLTIFWADDGLDTGPVLLQRECDVHINDTVDSLYSRFMMPEGIKAMVEAVRQIESGRAPAIAQYHPDHSYDQMVKKSTAEINWNQSGLSLHNFIRGHDKVRVPGAGLMARKSHFMA------------PS-SIQGLSDPAVLHNHGLLIRGSDNQWINIAQLKFEDTGKTVQASKYGKGDEITTMADLSEDERAMEIPLMKIWKSILMGSDIEPESDFFKLGGTSMDVTRIIEQIKCNFNVELKIDHIYLYSTFDTLFKWIVLRKRGGGSQKKLHYDAVIINANKMTFPIPHQIFINNEFVNSESGKEYDSKNPSDESVICRVSYSSKKDVDIAVKAAKEAFEFGEWGKMSARDRGRILYKLADLMEEHAEELATLESLDSGAVYTLALKTHIGMSIETFRYFAGWCDKIQGSTIPISNARPNKNLSFTKKEPIGVCGIITPWNYPLMMLAWKVAACLAAGNTVVLKPAQVTPLASLKFCELSVEAGFPSGVINVLPGSGAIAGTAISEHPDIRKLGFTGSTAIGQTIMSSCAKSNLKKCSLELGGKSPLIIFSDCDMDKAVKSACSSVFFNKGENCIAAGRIFVDVRIHDVFLKLVVEDVKKMKIGDPLDRSVDHGPQNHEIHLLKLLEFCDIGVKEGAKLVFGGKRCDRKG 796 HSP 2 Score: 146.362 bits (368), Expect = 1.575e-35 Identity = 68/70 (97.14%), Postives = 69/70 (98.57%), Query Frame = 1
Query: 37 MILYKFLKSYNLKLFQHLHFHNFNPRMKIAIIGQSIFGAQVYKELKNEGHDIVGVFTIPDRNGRSDPLGI 246
MILYKFLKSYNLKLFQHLHFHNFNPRMKIAIIGQSIFGAQVYKELKNEGHDIVGVFTIPDRNGRSDPL +
Sbjct: 1 MILYKFLKSYNLKLFQHLHFHNFNPRMKIAIIGQSIFGAQVYKELKNEGHDIVGVFTIPDRNGRSDPLAM 70
BLAST of 10-formyltetrahydrofolate dehydrogenase vs. Planmine SMEST
Match: SMESG000016195.1 (SMESG000016195.1) HSP 1 Score: 465.307 bits (1196), Expect = 2.727e-152 Identity = 244/526 (46.39%), Postives = 344/526 (65.40%), Query Frame = 3
Query: 1434 IDHIYLYSTFDTLFKWIVLRKRGGGSQKKLHYDAVIINANKMTFPIPHQIFINNEFVNSESGKEYDSKNPSDESVICRVSYSSXXXXXXXXXXXXXXFEFGE-WGKMSARDRGRILYKLADLMEEHAEELATLESLDSGAVYTLALKTHIGMSIETFRYFAGWCDKIQGSTIPISNARPNKNLSFTKKEPIGVCGIITPWNYPLMMLAWKVAACLAAGNTVVLKPAQVTPLASLKFCELSVEAGFPPGVINVLPGSGAIAGTAISEHPDIRKLGFTGSTAIGQTIMSSCAKSNLKKCSLELGGKSPLIIFSDCDMDKAVKSACSSVFFNKGENCIAAGRIFVDVRIHDVFLKLVVEDVKKMKIGDPLDRSVDHGPQNHEIHLLKLLEFCDIGVKEGAKLVFGGKRCDRKGYFMEPTIFTSVTDDMYIAREESFGPIMIISKFYDIDEVIVRANKTEYGLASGVFTNDISKALRVADAIDAGTVFINTYNKTDVAAPFGGFKQSGFGKDLGQEALNEYLKTKTVTVE 3008
+ I + F LF+ ++L + S K + N K+ + +IFINNE+ +S S K + +KNP+ IC+V+ K+D+D AV AA +AF+ G W KM A DRG ++YKLA L+ A+ LA LE+LDSG ++A + ++I+ + Y+AGW DK G IPI + FT+ EP+GVCG I PWN+PL+M AWK+A L+ GNTVVLK A+ TPL + L+ EAGFPPGV+N++PG G AG A+ HP + K+ FTGST +GQ I C ++N+K+ +LELGGKSP I+F+D D D AVK++ ++FFN G+ C A RI+V+ +I+D F++ +V + K +G+P D +VD GPQ E + K+L F D G EGA++ GGK+ KG+F+EPTIFT V D M IA+EE FGP+M I KF D +EVI RAN EYGLA+ +FT DI K+L V ++ AGTV++N Y+ D AAPFGG+K SG G++LG+ L+ Y + K VT++
Sbjct: 1 MSKIMISKKFSILFRPLLLNSKCFSSLAK----PITQNDIKVHY---TKIFINNEWHDSVSKKTFPTKNPATGQDICQVAEGGKEDIDKAVTAANKAFQLGSPWRKMDAADRGSLMYKLAQLIRRDADYLAALETLDSGKPVSIARAADVELTIKCYEYYAGWADKNHGKVIPIRG----DYIGFTRHEPVGVCGQIIPWNFPLLMQAWKLAPALSMGNTVVLKTAEQTPLTANYVASLAAEAGFPPGVVNIVPGMGPTAGAALVTHPKVDKIAFTGSTEVGQIISKHCNENNIKRLTLELGGKSPNIVFADADFDNAVKTSYFALFFNMGQCCCAGSRIYVEEKIYDKFVEAMVAEAKSKVVGNPFD-NVDQGPQIDEEQMNKILGFIDSGKSEGAQMCTGGKQIGSKGFFIEPTIFTKVEDSMRIAKEEIFGPVMQIMKFKDTNEVIARANNNEYGLAASIFTQDIDKSLHVTQSLRAGTVWVNCYDVFDAAAPFGGYKSSGVGRELGEYGLSNYTEVKMVTIK 514 The following BLAST results are available for this feature:
BLAST of 10-formyltetrahydrofolate dehydrogenase vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of 10-formyltetrahydrofolate dehydrogenase vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of 10-formyltetrahydrofolate dehydrogenase vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of 10-formyltetrahydrofolate dehydrogenase vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of 10-formyltetrahydrofolate dehydrogenase vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of 10-formyltetrahydrofolate dehydrogenase vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of 10-formyltetrahydrofolate dehydrogenase vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of 10-formyltetrahydrofolate dehydrogenase vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of 10-formyltetrahydrofolate dehydrogenase vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of 10-formyltetrahydrofolate dehydrogenase vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of 10-formyltetrahydrofolate dehydrogenase vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 5
BLAST of 10-formyltetrahydrofolate dehydrogenase vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of 10-formyltetrahydrofolate dehydrogenase vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of 10-formyltetrahydrofolate dehydrogenase vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30008441 ID=SMED30008441|Name=10-formyltetrahydrofolate dehydrogenase|organism=Schmidtea mediterranea sexual|type=transcript|length=3402bpback to top protein sequence of SMED30008441-orf-1 >SMED30008441-orf-1 ID=SMED30008441-orf-1|Name=SMED30008441-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=858bp MEAIDLGTKVFKIPKWRVNNQIIKEVFEEYRSINAELNVLAFCTQFIPMEback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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