slc1a-4
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny AppSub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30008388 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 8
Homology
BLAST of slc1a-4 vs. Ensembl Human
Match: SLC1A2 (solute carrier family 1 member 2 [Source:HGNC Symbol;Acc:HGNC:10940]) HSP 1 Score: 287.73 bits (735), Expect = 1.273e-95 Identity = 190/404 (47.03%), Postives = 271/404 (67.08%), Query Frame = 1
Query: 136 RKIHLKKFLSNNENILFVLTVFSVFTGLLAGFFIKSTFIVNEYQIYLISFPGEXXXXXXXXXXXXXXXXXXXXXXXXXETKSSGKIGLYTVLYYGITTSISLIMGMVLVVTIHPGNPKIKNLQPLENTGP---TSNIGALESIFDLIRNIFPPNLIEGCFRQVATNYA--------IEKEN--------IYKNFTEFPRN---ISKLTITMVESTNILGLVFFSITFGLILGQLGNKGKKMFQFFEVLNQVIMTMVTYIMWYFPXXXXXXXXXXXXXXXNLESAASSLGLYIMTVLLGLFIHGGIVLPLMYFIVCKKNPYWFFRALPQAWLASFGTASSTATLPITFKCLESNKLVSKKVTRFVLPIGATINMDGTALYEAVASIFIAQINGMVLSFGQIFSMS 1281
R + L+ +N+L LTVF V G + G ++ ++ + LI+FPG++LM MLKMLILPL+ SSLITGLS L+ K+SG++G ++YY TT I+ ++G++LV+ IHPGNPK+K + GP + +L++ DLIRN+FP NL++ CF+Q+ T E+ N + + TE P + K + + N+LGL+ F I FG+ +G++G++ K M FF +LN+++M +V IMWY P+GI LI GKI+ IK+LE A LG+Y++TV++GL IHGGI LPL+YF+V +KNP+ FF + QAW+ + GTASS TLP+TF+CLE N + K+VTRFVLP+GATINMDGTALYEAVA+IFIAQ+NG+VL GQI ++S
Sbjct: 31 RHLGLRLCDKLGKNLLLTLTVFGVILGAVCGGLLRLASPIHPDVVMLIAFPGDILMRMLKMLILPLIISSLITGLSGLDAKASGRLGTRAMVYYMSTTIIAAVLGVILVLAIHPGNPKLK-----KQLGPGKKNDEVSSLDAFLDLIRNLFPENLVQACFQQIQTVTKKVLVAPPPDEEANATSAVVSLLNETVTEVPEETKMVIKKGLEFKDGMNVLGLIGFFIAFGIAMGKMGDQAKLMVDFFNILNEIVMKLVIMIMWYSPLGIACLICGKIIAIKDLEVVARQLGMYMVTVIIGLIIHGGIFLPLIYFVVTRKNPFSFFAGIFQAWITALGTASSAGTLPVTFRCLEENLGIDKRVTRFVLPVGATINMDGTALYEAVAAIFIAQMNGVVLDGGQIVTVS 429 HSP 2 Score: 83.5741 bits (205), Expect = 1.273e-95 Identity = 40/80 (50.00%), Postives = 60/80 (75.00%), Query Frame = 2
Query: 1280 ATFAAIGASCVPSSGLVTVIPALASVGLPISDITLILTVDWFLDRVRTTINVLGDSLGSGIIESLLENDKIEIDWINNSD 1519
AT A++GA+ +PS+GLVT++ L +VGLP DI+L++ VDW LDR+RT++NV+GDS G+GI+ L K E+D I++
Sbjct: 432 ATLASVGAASIPSAGLVTMLLILTAVGLPTEDISLLVAVDWLLDRMRTSVNVVGDSFGAGIVYHL---SKSELDTIDSQH 508
BLAST of slc1a-4 vs. Ensembl Human
Match: SLC1A2 (solute carrier family 1 member 2 [Source:HGNC Symbol;Acc:HGNC:10940]) HSP 1 Score: 287.345 bits (734), Expect = 1.442e-95 Identity = 190/404 (47.03%), Postives = 271/404 (67.08%), Query Frame = 1
Query: 136 RKIHLKKFLSNNENILFVLTVFSVFTGLLAGFFIKSTFIVNEYQIYLISFPGEXXXXXXXXXXXXXXXXXXXXXXXXXETKSSGKIGLYTVLYYGITTSISLIMGMVLVVTIHPGNPKIKNLQPLENTGP---TSNIGALESIFDLIRNIFPPNLIEGCFRQVATNYA--------IEKEN--------IYKNFTEFPRN---ISKLTITMVESTNILGLVFFSITFGLILGQLGNKGKKMFQFFEVLNQVIMTMVTYIMWYFPXXXXXXXXXXXXXXXNLESAASSLGLYIMTVLLGLFIHGGIVLPLMYFIVCKKNPYWFFRALPQAWLASFGTASSTATLPITFKCLESNKLVSKKVTRFVLPIGATINMDGTALYEAVASIFIAQINGMVLSFGQIFSMS 1281
R + L+ +N+L LTVF V G + G ++ ++ + LI+FPG++LM MLKMLILPL+ SSLITGLS L+ K+SG++G ++YY TT I+ ++G++LV+ IHPGNPK+K + GP + +L++ DLIRN+FP NL++ CF+Q+ T E+ N + + TE P + K + + N+LGL+ F I FG+ +G++G++ K M FF +LN+++M +V IMWY P+GI LI GKI+ IK+LE A LG+Y++TV++GL IHGGI LPL+YF+V +KNP+ FF + QAW+ + GTASS TLP+TF+CLE N + K+VTRFVLP+GATINMDGTALYEAVA+IFIAQ+NG+VL GQI ++S
Sbjct: 22 RHLGLRLCDKLGKNLLLTLTVFGVILGAVCGGLLRLASPIHPDVVMLIAFPGDILMRMLKMLILPLIISSLITGLSGLDAKASGRLGTRAMVYYMSTTIIAAVLGVILVLAIHPGNPKLK-----KQLGPGKKNDEVSSLDAFLDLIRNLFPENLVQACFQQIQTVTKKVLVAPPPDEEANATSAVVSLLNETVTEVPEETKMVIKKGLEFKDGMNVLGLIGFFIAFGIAMGKMGDQAKLMVDFFNILNEIVMKLVIMIMWYSPLGIACLICGKIIAIKDLEVVARQLGMYMVTVIIGLIIHGGIFLPLIYFVVTRKNPFSFFAGIFQAWITALGTASSAGTLPVTFRCLEENLGIDKRVTRFVLPVGATINMDGTALYEAVAAIFIAQMNGVVLDGGQIVTVS 420 HSP 2 Score: 83.5741 bits (205), Expect = 1.442e-95 Identity = 40/80 (50.00%), Postives = 60/80 (75.00%), Query Frame = 2
Query: 1280 ATFAAIGASCVPSSGLVTVIPALASVGLPISDITLILTVDWFLDRVRTTINVLGDSLGSGIIESLLENDKIEIDWINNSD 1519
AT A++GA+ +PS+GLVT++ L +VGLP DI+L++ VDW LDR+RT++NV+GDS G+GI+ L K E+D I++
Sbjct: 423 ATLASVGAASIPSAGLVTMLLILTAVGLPTEDISLLVAVDWLLDRMRTSVNVVGDSFGAGIVYHL---SKSELDTIDSQH 499
BLAST of slc1a-4 vs. Ensembl Human
Match: SLC1A2 (solute carrier family 1 member 2 [Source:HGNC Symbol;Acc:HGNC:10940]) HSP 1 Score: 287.345 bits (734), Expect = 1.442e-95 Identity = 190/404 (47.03%), Postives = 271/404 (67.08%), Query Frame = 1
Query: 136 RKIHLKKFLSNNENILFVLTVFSVFTGLLAGFFIKSTFIVNEYQIYLISFPGEXXXXXXXXXXXXXXXXXXXXXXXXXETKSSGKIGLYTVLYYGITTSISLIMGMVLVVTIHPGNPKIKNLQPLENTGP---TSNIGALESIFDLIRNIFPPNLIEGCFRQVATNYA--------IEKEN--------IYKNFTEFPRN---ISKLTITMVESTNILGLVFFSITFGLILGQLGNKGKKMFQFFEVLNQVIMTMVTYIMWYFPXXXXXXXXXXXXXXXNLESAASSLGLYIMTVLLGLFIHGGIVLPLMYFIVCKKNPYWFFRALPQAWLASFGTASSTATLPITFKCLESNKLVSKKVTRFVLPIGATINMDGTALYEAVASIFIAQINGMVLSFGQIFSMS 1281
R + L+ +N+L LTVF V G + G ++ ++ + LI+FPG++LM MLKMLILPL+ SSLITGLS L+ K+SG++G ++YY TT I+ ++G++LV+ IHPGNPK+K + GP + +L++ DLIRN+FP NL++ CF+Q+ T E+ N + + TE P + K + + N+LGL+ F I FG+ +G++G++ K M FF +LN+++M +V IMWY P+GI LI GKI+ IK+LE A LG+Y++TV++GL IHGGI LPL+YF+V +KNP+ FF + QAW+ + GTASS TLP+TF+CLE N + K+VTRFVLP+GATINMDGTALYEAVA+IFIAQ+NG+VL GQI ++S
Sbjct: 22 RHLGLRLCDKLGKNLLLTLTVFGVILGAVCGGLLRLASPIHPDVVMLIAFPGDILMRMLKMLILPLIISSLITGLSGLDAKASGRLGTRAMVYYMSTTIIAAVLGVILVLAIHPGNPKLK-----KQLGPGKKNDEVSSLDAFLDLIRNLFPENLVQACFQQIQTVTKKVLVAPPPDEEANATSAVVSLLNETVTEVPEETKMVIKKGLEFKDGMNVLGLIGFFIAFGIAMGKMGDQAKLMVDFFNILNEIVMKLVIMIMWYSPLGIACLICGKIIAIKDLEVVARQLGMYMVTVIIGLIIHGGIFLPLIYFVVTRKNPFSFFAGIFQAWITALGTASSAGTLPVTFRCLEENLGIDKRVTRFVLPVGATINMDGTALYEAVAAIFIAQMNGVVLDGGQIVTVS 420 HSP 2 Score: 83.5741 bits (205), Expect = 1.442e-95 Identity = 40/80 (50.00%), Postives = 60/80 (75.00%), Query Frame = 2
Query: 1280 ATFAAIGASCVPSSGLVTVIPALASVGLPISDITLILTVDWFLDRVRTTINVLGDSLGSGIIESLLENDKIEIDWINNSD 1519
AT A++GA+ +PS+GLVT++ L +VGLP DI+L++ VDW LDR+RT++NV+GDS G+GI+ L K E+D I++
Sbjct: 423 ATLASVGAASIPSAGLVTMLLILTAVGLPTEDISLLVAVDWLLDRMRTSVNVVGDSFGAGIVYHL---SKSELDTIDSQH 499
BLAST of slc1a-4 vs. Ensembl Human
Match: SLC1A2 (solute carrier family 1 member 2 [Source:HGNC Symbol;Acc:HGNC:10940]) HSP 1 Score: 287.345 bits (734), Expect = 1.454e-95 Identity = 190/404 (47.03%), Postives = 271/404 (67.08%), Query Frame = 1
Query: 136 RKIHLKKFLSNNENILFVLTVFSVFTGLLAGFFIKSTFIVNEYQIYLISFPGEXXXXXXXXXXXXXXXXXXXXXXXXXETKSSGKIGLYTVLYYGITTSISLIMGMVLVVTIHPGNPKIKNLQPLENTGP---TSNIGALESIFDLIRNIFPPNLIEGCFRQVATNYA--------IEKEN--------IYKNFTEFPRN---ISKLTITMVESTNILGLVFFSITFGLILGQLGNKGKKMFQFFEVLNQVIMTMVTYIMWYFPXXXXXXXXXXXXXXXNLESAASSLGLYIMTVLLGLFIHGGIVLPLMYFIVCKKNPYWFFRALPQAWLASFGTASSTATLPITFKCLESNKLVSKKVTRFVLPIGATINMDGTALYEAVASIFIAQINGMVLSFGQIFSMS 1281
R + L+ +N+L LTVF V G + G ++ ++ + LI+FPG++LM MLKMLILPL+ SSLITGLS L+ K+SG++G ++YY TT I+ ++G++LV+ IHPGNPK+K + GP + +L++ DLIRN+FP NL++ CF+Q+ T E+ N + + TE P + K + + N+LGL+ F I FG+ +G++G++ K M FF +LN+++M +V IMWY P+GI LI GKI+ IK+LE A LG+Y++TV++GL IHGGI LPL+YF+V +KNP+ FF + QAW+ + GTASS TLP+TF+CLE N + K+VTRFVLP+GATINMDGTALYEAVA+IFIAQ+NG+VL GQI ++S
Sbjct: 28 RHLGLRLCDKLGKNLLLTLTVFGVILGAVCGGLLRLASPIHPDVVMLIAFPGDILMRMLKMLILPLIISSLITGLSGLDAKASGRLGTRAMVYYMSTTIIAAVLGVILVLAIHPGNPKLK-----KQLGPGKKNDEVSSLDAFLDLIRNLFPENLVQACFQQIQTVTKKVLVAPPPDEEANATSAVVSLLNETVTEVPEETKMVIKKGLEFKDGMNVLGLIGFFIAFGIAMGKMGDQAKLMVDFFNILNEIVMKLVIMIMWYSPLGIACLICGKIIAIKDLEVVARQLGMYMVTVIIGLIIHGGIFLPLIYFVVTRKNPFSFFAGIFQAWITALGTASSAGTLPVTFRCLEENLGIDKRVTRFVLPVGATINMDGTALYEAVAAIFIAQMNGVVLDGGQIVTVS 426 HSP 2 Score: 83.9593 bits (206), Expect = 1.454e-95 Identity = 40/80 (50.00%), Postives = 60/80 (75.00%), Query Frame = 2
Query: 1280 ATFAAIGASCVPSSGLVTVIPALASVGLPISDITLILTVDWFLDRVRTTINVLGDSLGSGIIESLLENDKIEIDWINNSD 1519
AT A++GA+ +PS+GLVT++ L +VGLP DI+L++ VDW LDR+RT++NV+GDS G+GI+ L K E+D I++
Sbjct: 429 ATLASVGAASIPSAGLVTMLLILTAVGLPTEDISLLVAVDWLLDRMRTSVNVVGDSFGAGIVYHL---SKSELDTIDSQH 505
BLAST of slc1a-4 vs. Ensembl Human
Match: SLC1A2 (solute carrier family 1 member 2 [Source:HGNC Symbol;Acc:HGNC:10940]) HSP 1 Score: 287.345 bits (734), Expect = 1.606e-95 Identity = 190/404 (47.03%), Postives = 271/404 (67.08%), Query Frame = 1
Query: 136 RKIHLKKFLSNNENILFVLTVFSVFTGLLAGFFIKSTFIVNEYQIYLISFPGEXXXXXXXXXXXXXXXXXXXXXXXXXETKSSGKIGLYTVLYYGITTSISLIMGMVLVVTIHPGNPKIKNLQPLENTGP---TSNIGALESIFDLIRNIFPPNLIEGCFRQVATNYA--------IEKEN--------IYKNFTEFPRN---ISKLTITMVESTNILGLVFFSITFGLILGQLGNKGKKMFQFFEVLNQVIMTMVTYIMWYFPXXXXXXXXXXXXXXXNLESAASSLGLYIMTVLLGLFIHGGIVLPLMYFIVCKKNPYWFFRALPQAWLASFGTASSTATLPITFKCLESNKLVSKKVTRFVLPIGATINMDGTALYEAVASIFIAQINGMVLSFGQIFSMS 1281
R + L+ +N+L LTVF V G + G ++ ++ + LI+FPG++LM MLKMLILPL+ SSLITGLS L+ K+SG++G ++YY TT I+ ++G++LV+ IHPGNPK+K + GP + +L++ DLIRN+FP NL++ CF+Q+ T E+ N + + TE P + K + + N+LGL+ F I FG+ +G++G++ K M FF +LN+++M +V IMWY P+GI LI GKI+ IK+LE A LG+Y++TV++GL IHGGI LPL+YF+V +KNP+ FF + QAW+ + GTASS TLP+TF+CLE N + K+VTRFVLP+GATINMDGTALYEAVA+IFIAQ+NG+VL GQI ++S
Sbjct: 31 RHLGLRLCDKLGKNLLLTLTVFGVILGAVCGGLLRLASPIHPDVVMLIAFPGDILMRMLKMLILPLIISSLITGLSGLDAKASGRLGTRAMVYYMSTTIIAAVLGVILVLAIHPGNPKLK-----KQLGPGKKNDEVSSLDAFLDLIRNLFPENLVQACFQQIQTVTKKVLVAPPPDEEANATSAVVSLLNETVTEVPEETKMVIKKGLEFKDGMNVLGLIGFFIAFGIAMGKMGDQAKLMVDFFNILNEIVMKLVIMIMWYSPLGIACLICGKIIAIKDLEVVARQLGMYMVTVIIGLIIHGGIFLPLIYFVVTRKNPFSFFAGIFQAWITALGTASSAGTLPVTFRCLEENLGIDKRVTRFVLPVGATINMDGTALYEAVAAIFIAQMNGVVLDGGQIVTVS 429 HSP 2 Score: 83.9593 bits (206), Expect = 1.606e-95 Identity = 40/80 (50.00%), Postives = 60/80 (75.00%), Query Frame = 2
Query: 1280 ATFAAIGASCVPSSGLVTVIPALASVGLPISDITLILTVDWFLDRVRTTINVLGDSLGSGIIESLLENDKIEIDWINNSD 1519
AT A++GA+ +PS+GLVT++ L +VGLP DI+L++ VDW LDR+RT++NV+GDS G+GI+ L K E+D I++
Sbjct: 432 ATLASVGAASIPSAGLVTMLLILTAVGLPTEDISLLVAVDWLLDRMRTSVNVVGDSFGAGIVYHL---SKSELDTIDSQH 508
BLAST of slc1a-4 vs. Ensembl Celegans
Match: glt-1 (Excitatory amino acid transporter [Source:UniProtKB/Swiss-Prot;Acc:Q10901]) HSP 1 Score: 296.59 bits (758), Expect = 1.112e-99 Identity = 186/379 (49.08%), Postives = 255/379 (67.28%), Query Frame = 1
Query: 169 NENILFVLTVFSVFTGLLAGFFIKSTFIVNEYQIYLISFPGEXXXXXXXXXXXXXXXXXXXXXXXXXETKSSGKIGLYTVLYYGITTSISLIMGMVLVVTIHPGNPKIKNLQPLENTGPTSNIGALESIFDLIRNIFPPNLIEGCFRQVATNYAIEKENIYKN--------FTEFPRNISKLTITMVESTNILGLVFFSITFGLILGQLGNKGKKMFQFFEVLNQVIMTMVTYIMWYFPXXXXXXXXXXXXXXXNLESAASSLGLYIMTVLLGLFIHGGIVLPLMYFIVCKKNPYWFFRALPQAWLASFGTASSTATLPITFKCLESNKLVSKKVTRFVLPIGATINMDGTALYEAVASIFIAQINGMVLSFGQIFSMS 1281
+N+L VLTV SV G L GF ++ ++ I ISFPGE+LM+MLKM+ILPL+ SSLI+GL+ L+ + SGK+G V YY TT+++++ G+ LV+ IHPG+P IK G T + ++++ DL+RN+FP N+++ F+QV T Y + + KN + K ++ N+LG++ F I G+ L QLG + M QFF ++++VIM +V +MWY P GIF LI+GKILEI +L A L +Y++TVL GL IH I LPL++F+ KKNPY F R L QAW+ + GTASS+ATLPITF CLE N V ++VTRFVLP+GATINMDGTALYEAVA+IFIAQING+ LSFGQ+ ++S
Sbjct: 6 RKNLLLVLTVSSVVLGALCGFLLRG-LQLSPQNIMYISFPGELLMHMLKMMILPLIMSSLISGLAQLDARQSGKLGSLAVTYYMFTTAVAVVTGIFLVLVIHPGDPTIKKEIGTGTEGKT--VSTVDTLLDLLRNMFPENVVQATFQQVQTKYIKVRPKVVKNNDSATLAALNNGSLDYVKASVEYTSGMNVLGVIVFCIAIGISLSQLGQEAHVMVQFFVIMDKVIMKLVMTVMWYSPFGIFCLIMGKILEIHDLADTARMLAMYMVTVLSGLAIHSLISLPLIFFVTTKKNPYVFMRGLFQAWITALGTASSSATLPITFNCLEENLGVDRRVTRFVLPVGATINMDGTALYEAVAAIFIAQINGVHLSFGQVVTVS 381 HSP 2 Score: 87.0409 bits (214), Expect = 1.112e-99 Identity = 39/69 (56.52%), Postives = 56/69 (81.16%), Query Frame = 2
Query: 1280 ATFAAIGASCVPSSGLVTVIPALASVGLPISDITLILTVDWFLDRVRTTINVLGDSLGSGIIESLLEND 1486
AT A+IGA+ VPS+GLVT++ L +VGLP+ D++LI+ VDW LDR+RT+INVLGD++G+GI+ + D
Sbjct: 384 ATLASIGAASVPSAGLVTMLLVLTAVGLPVKDVSLIVAVDWLLDRIRTSINVLGDAMGAGIVYHYSKAD 452
BLAST of slc1a-4 vs. Ensembl Celegans
Match: glt-1 (Excitatory amino acid transporter [Source:UniProtKB/Swiss-Prot;Acc:Q10901]) HSP 1 Score: 296.204 bits (757), Expect = 1.670e-99 Identity = 186/379 (49.08%), Postives = 255/379 (67.28%), Query Frame = 1
Query: 169 NENILFVLTVFSVFTGLLAGFFIKSTFIVNEYQIYLISFPGEXXXXXXXXXXXXXXXXXXXXXXXXXETKSSGKIGLYTVLYYGITTSISLIMGMVLVVTIHPGNPKIKNLQPLENTGPTSNIGALESIFDLIRNIFPPNLIEGCFRQVATNYAIEKENIYKN--------FTEFPRNISKLTITMVESTNILGLVFFSITFGLILGQLGNKGKKMFQFFEVLNQVIMTMVTYIMWYFPXXXXXXXXXXXXXXXNLESAASSLGLYIMTVLLGLFIHGGIVLPLMYFIVCKKNPYWFFRALPQAWLASFGTASSTATLPITFKCLESNKLVSKKVTRFVLPIGATINMDGTALYEAVASIFIAQINGMVLSFGQIFSMS 1281
+N+L VLTV SV G L GF ++ ++ I ISFPGE+LM+MLKM+ILPL+ SSLI+GL+ L+ + SGK+G V YY TT+++++ G+ LV+ IHPG+P IK G T + ++++ DL+RN+FP N+++ F+QV T Y + + KN + K ++ N+LG++ F I G+ L QLG + M QFF ++++VIM +V +MWY P GIF LI+GKILEI +L A L +Y++TVL GL IH I LPL++F+ KKNPY F R L QAW+ + GTASS+ATLPITF CLE N V ++VTRFVLP+GATINMDGTALYEAVA+IFIAQING+ LSFGQ+ ++S
Sbjct: 17 RKNLLLVLTVSSVVLGALCGFLLRG-LQLSPQNIMYISFPGELLMHMLKMMILPLIMSSLISGLAQLDARQSGKLGSLAVTYYMFTTAVAVVTGIFLVLVIHPGDPTIKKEIGTGTEGKT--VSTVDTLLDLLRNMFPENVVQATFQQVQTKYIKVRPKVVKNNDSATLAALNNGSLDYVKASVEYTSGMNVLGVIVFCIAIGISLSQLGQEAHVMVQFFVIMDKVIMKLVMTVMWYSPFGIFCLIMGKILEIHDLADTARMLAMYMVTVLSGLAIHSLISLPLIFFVTTKKNPYVFMRGLFQAWITALGTASSSATLPITFNCLEENLGVDRRVTRFVLPVGATINMDGTALYEAVAAIFIAQINGVHLSFGQVVTVS 392 HSP 2 Score: 87.0409 bits (214), Expect = 1.670e-99 Identity = 39/69 (56.52%), Postives = 56/69 (81.16%), Query Frame = 2
Query: 1280 ATFAAIGASCVPSSGLVTVIPALASVGLPISDITLILTVDWFLDRVRTTINVLGDSLGSGIIESLLEND 1486
AT A+IGA+ VPS+GLVT++ L +VGLP+ D++LI+ VDW LDR+RT+INVLGD++G+GI+ + D
Sbjct: 395 ATLASIGAASVPSAGLVTMLLVLTAVGLPVKDVSLIVAVDWLLDRIRTSINVLGDAMGAGIVYHYSKAD 463
BLAST of slc1a-4 vs. Ensembl Celegans
Match: glt-6 (Putative sodium-dependent excitatory amino acid transporter glt-6 [Source:UniProtKB/Swiss-Prot;Acc:Q21751]) HSP 1 Score: 264.618 bits (675), Expect = 4.945e-86 Identity = 166/383 (43.34%), Postives = 249/383 (65.01%), Query Frame = 1
Query: 136 RKIHLKKFLSNNENILFVLTVFSVFTGLLAGFFIKSTFIVNEYQIYLISFPGEXXXXXXXXXXXXXXXXXXXXXXXXXETKSSGKIGLYTVLYYGITTSISLIMGMVLVVTIHPGNPKIKNLQPLENTGPTSNIGALESIFDLIRNIFPPNLIEGCFRQVATNY-AIEKENIYKNFTEFPRNISKLTITMVESTNILGLVFFSITFGLILGQLGNKGKKMFQFFEVLNQVIMTMVTYIMWYFPXXXXXXXXXXXXXXXNLESAASSLGLYIMTVLLGLFIHGGIVLPLMYFIVCKKNPYWFFRALPQAWLASFGTASSTATLPITFKCLESNKLVSKKVTRFVLPIGATINMDGTALYEAVASIFIAQINGMVLSFGQIFSMS 1281
R+ + +F EN L V+T+FSVF G++ GF ++ + E + LI+FPGE+ M +LKM+ILPL+ SSLI+ L+ ++ K SG++G TVLYY T ++ I+G+ LV IHPG+P IK + N+ L++ DL+RN+FP N+I+ F ++ T Y AI + KN T I K +I M + NILG++ F FG+++ QLG + + + FF +L+ VIM V +MW+ P+GI LI G +LE+ ++ AS L LY+ TV GL +H I +PLMYF + ++NP F+ + QA + +FGTAS ATLP++ +CLE + V ++++RFVLP+G+TINMDG ALYEAVA IFIAQ+N + LS ++ ++S
Sbjct: 5 RRDDIVQFC--RENTLLVMTMFSVFLGVVLGFGLRPLNLSQE-TLQLINFPGEIFMQVLKMMILPLIFSSLISALAQMDAKESGQMGASTVLYYLSTAVLATILGIFLVTVIHPGDPSIKGTD-ISEAPSDGNVSPLDTFLDLVRNMFPENIIQATFERMQTTYVAIRPKIASKNGTS-GNIIVKRSIGMTKGMNILGIIVFCTGFGIVISQLGERARIVVDFFVILDAVIMRWVVTLMWFAPLGITCLICGNLLELDDISDIASVLALYVFTVCAGLILHTIITVPLMYFFITRENPLPIFKGMIQAAVTAFGTASGGATLPMSMQCLEDHCGVDRRISRFVLPLGSTINMDGNALYEAVAVIFIAQLNNVQLSLAEVLTVS 382 HSP 2 Score: 73.559 bits (179), Expect = 4.945e-86 Identity = 36/86 (41.86%), Postives = 59/86 (68.60%), Query Frame = 2
Query: 1280 ATFAAIGASCVPSSGLVTVIPALASVGLPISDITLILTVDWFLDRVRTTINVLGDSLGSGIIESLLEN--DKIEIDWINNSDLDGK 1531
AT A+IG VP+ GLV+++ L +VGLP+ D++++ TVDW LDRVRT +NVLGD+ + +++ LL+ D+ + ++L G+
Sbjct: 385 ATIASIGLGSVPA-GLVSILLILNTVGLPVRDVSMLFTVDWLLDRVRTAVNVLGDAFAASMVQHLLQKKLDQADARHDYKTELKGE 469
BLAST of slc1a-4 vs. Ensembl Celegans
Match: glt-5 (Amino acid transporter [Source:UniProtKB/TrEMBL;Acc:O18210]) HSP 1 Score: 250.751 bits (639), Expect = 4.113e-85 Identity = 161/371 (43.40%), Postives = 238/371 (64.15%), Query Frame = 1
Query: 172 ENILFVLTVFSVFTGLLAGFFIKSTFIVNEYQIYLISFPGEXXXXXXXXXXXXXXXXXXXXXXXXXETKSSGKIGLYTVLYYGITTSISLIMGMVLVVTIHPGNPKIKNLQPLENTGPTSNIGALESIFDLIRNIFPPNLIEGCFRQVATNYAIEKENIYKNFTEFPRNISKLTITMVESTNILGLVFFSITFGLILGQLGNKGKKMFQFFEVLNQVIMTMVTYIMWYFPXXXXXXXXXXXXXXXNLESAASSLGLYIMTVLLGLFIHGGIVLPLMYFIVCKKNPYWFFRALPQAWLASFGTASSTATLPITFKCLESNKL-VSKKVTRFVLPIGATINMDGTALYEAVASIFIAQINGMVLSFGQIFSMS 1281
+N+L ++T+ + G++ G +++ + I + FPGE+ MNMLK ++LPL+ +S+++GLS L+ K+SG++G V+YY ITT+ ++I+G+++V I PG+P IK + G +N+ A + DL RN FP N++ F QV TNY I + + E L V+ N+LG++ F I GL++ ++G + K + F L+ VI MV IMW PIGI LI K+LE+ +L A LGL++ TV+LGL I I LPL+YFI + NPY F + L QA + + GT+SS A+LP+TF+CL NKL + +VT+FVLP+GA +NMDGTALYEA ASIFIAQ+NG+ LS GQI ++S
Sbjct: 18 KNMLLLMTMAGIVMGVIIGGVLRTADPSPDV-IRYVGFPGELFMNMLKAMVLPLIAASIVSGLSQLDGKTSGRLGSRAVMYYAITTTHAVILGIIVVSIIQPGDPTIKQKMGYDKEGEAANVSAAQKFLDLFRNAFPENIMRATFSQVQTNY-INQTHSNGATHEV------LHTGYVDGMNVLGIIVFCIVMGLVVSRIGEEAKALANLFHALDVVITRMVMLIMWLGPIGIPSLIAQKMLEVSDLWLTARMLGLFVFTVILGLAIQAFITLPLIYFIGTRHNPYTFLKGLGQAIMTALGTSSSAASLPVTFRCL--NKLGIDPRVTKFVLPVGAMVNMDGTALYEATASIFIAQMNGLELSIGQIVTVS 378 HSP 2 Score: 84.3445 bits (207), Expect = 4.113e-85 Identity = 37/65 (56.92%), Postives = 54/65 (83.08%), Query Frame = 2
Query: 1280 ATFAAIGASCVPSSGLVTVIPALASVGLPISDITLILTVDWFLDRVRTTINVLGDSLGSGIIESL 1474
AT A+IGA+ +PS+GLVT++ L ++GLP +DI+LIL VDWFLDR+RT++NV+GD+LG G + +
Sbjct: 381 ATLASIGAASIPSAGLVTMLIVLTALGLPANDISLILAVDWFLDRLRTSVNVIGDALGCGFVHHI 445
BLAST of slc1a-4 vs. Ensembl Celegans
Match: glt-3 (Putative sodium-dependent excitatory amino acid transporter glt-3 [Source:UniProtKB/Swiss-Prot;Acc:Q21353]) HSP 1 Score: 238.81 bits (608), Expect = 5.249e-80 Identity = 165/377 (43.77%), Postives = 246/377 (65.25%), Query Frame = 1
Query: 169 NENILFVLTVFSVFTGLLAGFFIKSTFIVNEYQIYLISFPGEXXXXXXXXXXXXXXXXXXXXXXXXXETKSSGKIGLYTVLYYGITTSISLIMGMVLVVTIHPGNPK-IKNLQP--LENTGPTSNIGALESIFDLIRNIFPPNLIEGCFRQVATNYAIEKENIYKNFTEF---PRNISKLTITMVESTNILGLVFFSITFGLILGQLGNKGKKMFQFFEVLNQVIMTMVTYIMWYFPXXXXXXXXXXXXXXXNLESAASSLGLYIMTVLLGLFIHGGIVLPLMYFIVCKKNPYWFFRALPQAWLASFGTASSTATLPITFKCLESNKLVSKKVTRFVLPIGATINMDGTALYEAVASIFIAQINGMVLSFGQIFSMS 1281
+++L VLT+ SV G++ GF I+ F + I LI FPGE+ M +++M+ILPL+ SS+I+ L+ + + + +IG+ T++YY ITT ++ G++LV +IHPG+P+ I L LENT + L++ D IRN+FP N+I+ F+QV T Y K + +N T + K T+T N+LGL+ F FG+IL LG++ + M FF VL+ +IM ++ +MW +PIGI L+ I++I NL A +L +Y++TV+ GL IH + LPL+YF+V KK+P+ F + QA +FGTASS ATLP+TF+ LE N + ++VTRFVLP+GATI MDGTALYEAVA IFIAQ++ + LS + ++S
Sbjct: 4 KKDLLLVLTIESVVLGVVLGFVIRP-FNPSNDTISLIGFPGEIFMQIVEMMILPLIMSSVISALAQVRARDARRIGIVTIIYYMITTFLATFTGIILVSSIHPGDPELIHELGEGTLENTA----LSTLDTFLDQIRNMFPENIIQATFQQVQTEYMPIKPSRVRNATSMNMTSEVLHKQTLTYTNEMNVLGLIVFCSGFGIILSILGDQARLMINFFIVLDAIIMRWISALMWCYPIGILSLVCKNIIDIDNLTETAQALAMYVVTVICGLMIHSLLTLPLLYFLVTKKSPFAFMTGMLQALATAFGTASSGATLPVTFRALEENLKIDRRVTRFVLPLGATITMDGTALYEAVAVIFIAQLHNIKLSLMDLVTIS 375 HSP 2 Score: 79.337 bits (194), Expect = 5.249e-80 Identity = 47/94 (50.00%), Postives = 61/94 (64.89%), Query Frame = 2
Query: 1283 TFAAIGASCVPSSGLVTVIPALASVGLPISDITLILTVDWFLDRVRTTINVLGDSLGSGIIE-----SLLENDKIE--------IDWINNSDLD 1525
T A+IG+ VP+ GL T++ L +VGLP D++L+LTVDW LDR+RT++NVLGDS G+GII SLLE D E ID +NN D
Sbjct: 379 TVASIGSGSVPA-GLDTIVIVLTTVGLPAKDLSLLLTVDWLLDRIRTSVNVLGDSFGAGIIHHLTRSSLLEADTDELIRQIREDIDILNNPHQD 471
BLAST of slc1a-4 vs. Ensembl Fly
Match: Eaat1 (gene:FBgn0026439 transcript:FBtr0079800) HSP 1 Score: 219.935 bits (559), Expect = 1.133e-73 Identity = 152/384 (39.58%), Postives = 235/384 (61.20%), Query Frame = 1
Query: 169 NENILFVLTVFSVFTGLLAGFFIK-STFIVNEYQIYLISFPGEXXXXXXXXXXXXXXXXXXXXXXXXXETKSSGKIGLYTVLYYGITTSISLIMGMVLVVTIHPGN-PKIKNLQPLENTGPTSNIGALESIFDLIRNIFPPNLIEGCFRQVATNYAIEKENIYKNFT---EFPRNISKLTITMVESTNILGLVFFSITFGLILGQLGNKGKKMFQFFEVLNQVIMTMVTYIMWYFPXXXXXXXXXXXXXXXNLESAASSLGLYIMTVLLGLFIHGGIVLPLMYFIVCKKNPYWFFRALPQAWLASFGTASSTATLPITFKCLESNKLVSKKVTRFVLPIGATINMDGTALYEAVASIFIAQINGMVLSFGQIFSMSYICSNWSL 1305
EN+L + TV VF G L GF IK ST ++ +I ISFPGE+ + MLK LI+PLL SS+ + + L+ S KI + YY +TT ++I+G+ LV T+ PG KI Q E+ S + +++ DL+RN+F N+I+ Q + IY+N + P + E +N+LGLV FS+ G +G++ KG+ + FF L++ +MT+ ++++W P+G+ FLI KI+E++++ + SLG Y +TV++GLF+HG + +++F+ ++ PY + L Q +FGT SS+AT+P+T KCL+ N + +VTRFV+P+GATINMDGTALYEAVA++FIAQ M SFG I ++S + S+
Sbjct: 16 QENVLTMATVIGVFVGGLIGFIIKNSTGEWSKREIMYISFPGEIFLRMLKCLIVPLLVSSITSAIGGLDLSMSSKIATRAITYYFVTTISAVILGICLVTTLRPGQGAKIVETQT-ESIDKASKVLTPDTLMDLVRNMFTDNIIQSTMFQ-------HRTEIYENTSISPAQPMENWEFKSAQREGSNVLGLVMFSVILGTTIGRMREKGQLLQDFFTTLSEAMMTITSWVIWISPLGVAFLIAAKIIEMESIAATIQSLGWYFITVMIGLFLHGFGTIAVIFFLGTRRLPYRYIAKLSQVLATAFGTGSSSATMPLTIKCLD-NMGIDPRVTRFVIPVGATINMDGTALYEAVAALFIAQYREMSYSFGTIVAVSITATAASI 390 HSP 2 Score: 77.411 bits (189), Expect = 1.133e-73 Identity = 38/77 (49.35%), Postives = 56/77 (72.73%), Query Frame = 2
Query: 1280 ATFAAIGASCVPSSGLVTVIPALASVGLPISDITLILTVDWFLDRVRTTINVLGDSLGSGIIESLLENDKIEIDWIN 1510
AT A+IGA+ +P +GLVT++ L +VGL D++LI+ VDW LDR RTTINV+ D+LG+ ++ L +ND +D +N
Sbjct: 385 ATAASIGAAGIPQAGLVTMVMVLDTVGLEPKDVSLIIAVDWLLDRFRTTINVMCDALGTILVNHLSKNDLASVDRLN 461
BLAST of slc1a-4 vs. Ensembl Fly
Match: Eaat1 (gene:FBgn0026439 transcript:FBtr0079801) HSP 1 Score: 219.935 bits (559), Expect = 1.133e-73 Identity = 152/384 (39.58%), Postives = 235/384 (61.20%), Query Frame = 1
Query: 169 NENILFVLTVFSVFTGLLAGFFIK-STFIVNEYQIYLISFPGEXXXXXXXXXXXXXXXXXXXXXXXXXETKSSGKIGLYTVLYYGITTSISLIMGMVLVVTIHPGN-PKIKNLQPLENTGPTSNIGALESIFDLIRNIFPPNLIEGCFRQVATNYAIEKENIYKNFT---EFPRNISKLTITMVESTNILGLVFFSITFGLILGQLGNKGKKMFQFFEVLNQVIMTMVTYIMWYFPXXXXXXXXXXXXXXXNLESAASSLGLYIMTVLLGLFIHGGIVLPLMYFIVCKKNPYWFFRALPQAWLASFGTASSTATLPITFKCLESNKLVSKKVTRFVLPIGATINMDGTALYEAVASIFIAQINGMVLSFGQIFSMSYICSNWSL 1305
EN+L + TV VF G L GF IK ST ++ +I ISFPGE+ + MLK LI+PLL SS+ + + L+ S KI + YY +TT ++I+G+ LV T+ PG KI Q E+ S + +++ DL+RN+F N+I+ Q + IY+N + P + E +N+LGLV FS+ G +G++ KG+ + FF L++ +MT+ ++++W P+G+ FLI KI+E++++ + SLG Y +TV++GLF+HG + +++F+ ++ PY + L Q +FGT SS+AT+P+T KCL+ N + +VTRFV+P+GATINMDGTALYEAVA++FIAQ M SFG I ++S + S+
Sbjct: 16 QENVLTMATVIGVFVGGLIGFIIKNSTGEWSKREIMYISFPGEIFLRMLKCLIVPLLVSSITSAIGGLDLSMSSKIATRAITYYFVTTISAVILGICLVTTLRPGQGAKIVETQT-ESIDKASKVLTPDTLMDLVRNMFTDNIIQSTMFQ-------HRTEIYENTSISPAQPMENWEFKSAQREGSNVLGLVMFSVILGTTIGRMREKGQLLQDFFTTLSEAMMTITSWVIWISPLGVAFLIAAKIIEMESIAATIQSLGWYFITVMIGLFLHGFGTIAVIFFLGTRRLPYRYIAKLSQVLATAFGTGSSSATMPLTIKCLD-NMGIDPRVTRFVIPVGATINMDGTALYEAVAALFIAQYREMSYSFGTIVAVSITATAASI 390 HSP 2 Score: 77.411 bits (189), Expect = 1.133e-73 Identity = 38/77 (49.35%), Postives = 56/77 (72.73%), Query Frame = 2
Query: 1280 ATFAAIGASCVPSSGLVTVIPALASVGLPISDITLILTVDWFLDRVRTTINVLGDSLGSGIIESLLENDKIEIDWIN 1510
AT A+IGA+ +P +GLVT++ L +VGL D++LI+ VDW LDR RTTINV+ D+LG+ ++ L +ND +D +N
Sbjct: 385 ATAASIGAAGIPQAGLVTMVMVLDTVGLEPKDVSLIIAVDWLLDRFRTTINVMCDALGTILVNHLSKNDLASVDRLN 461
BLAST of slc1a-4 vs. Ensembl Fly
Match: Eaat1 (gene:FBgn0026439 transcript:FBtr0303876) HSP 1 Score: 219.935 bits (559), Expect = 1.133e-73 Identity = 152/384 (39.58%), Postives = 235/384 (61.20%), Query Frame = 1
Query: 169 NENILFVLTVFSVFTGLLAGFFIK-STFIVNEYQIYLISFPGEXXXXXXXXXXXXXXXXXXXXXXXXXETKSSGKIGLYTVLYYGITTSISLIMGMVLVVTIHPGN-PKIKNLQPLENTGPTSNIGALESIFDLIRNIFPPNLIEGCFRQVATNYAIEKENIYKNFT---EFPRNISKLTITMVESTNILGLVFFSITFGLILGQLGNKGKKMFQFFEVLNQVIMTMVTYIMWYFPXXXXXXXXXXXXXXXNLESAASSLGLYIMTVLLGLFIHGGIVLPLMYFIVCKKNPYWFFRALPQAWLASFGTASSTATLPITFKCLESNKLVSKKVTRFVLPIGATINMDGTALYEAVASIFIAQINGMVLSFGQIFSMSYICSNWSL 1305
EN+L + TV VF G L GF IK ST ++ +I ISFPGE+ + MLK LI+PLL SS+ + + L+ S KI + YY +TT ++I+G+ LV T+ PG KI Q E+ S + +++ DL+RN+F N+I+ Q + IY+N + P + E +N+LGLV FS+ G +G++ KG+ + FF L++ +MT+ ++++W P+G+ FLI KI+E++++ + SLG Y +TV++GLF+HG + +++F+ ++ PY + L Q +FGT SS+AT+P+T KCL+ N + +VTRFV+P+GATINMDGTALYEAVA++FIAQ M SFG I ++S + S+
Sbjct: 16 QENVLTMATVIGVFVGGLIGFIIKNSTGEWSKREIMYISFPGEIFLRMLKCLIVPLLVSSITSAIGGLDLSMSSKIATRAITYYFVTTISAVILGICLVTTLRPGQGAKIVETQT-ESIDKASKVLTPDTLMDLVRNMFTDNIIQSTMFQ-------HRTEIYENTSISPAQPMENWEFKSAQREGSNVLGLVMFSVILGTTIGRMREKGQLLQDFFTTLSEAMMTITSWVIWISPLGVAFLIAAKIIEMESIAATIQSLGWYFITVMIGLFLHGFGTIAVIFFLGTRRLPYRYIAKLSQVLATAFGTGSSSATMPLTIKCLD-NMGIDPRVTRFVIPVGATINMDGTALYEAVAALFIAQYREMSYSFGTIVAVSITATAASI 390 HSP 2 Score: 77.411 bits (189), Expect = 1.133e-73 Identity = 38/77 (49.35%), Postives = 56/77 (72.73%), Query Frame = 2
Query: 1280 ATFAAIGASCVPSSGLVTVIPALASVGLPISDITLILTVDWFLDRVRTTINVLGDSLGSGIIESLLENDKIEIDWIN 1510
AT A+IGA+ +P +GLVT++ L +VGL D++LI+ VDW LDR RTTINV+ D+LG+ ++ L +ND +D +N
Sbjct: 385 ATAASIGAAGIPQAGLVTMVMVLDTVGLEPKDVSLIIAVDWLLDRFRTTINVMCDALGTILVNHLSKNDLASVDRLN 461
BLAST of slc1a-4 vs. Ensembl Fly
Match: Eaat1 (gene:FBgn0026439 transcript:FBtr0079802) HSP 1 Score: 219.935 bits (559), Expect = 1.133e-73 Identity = 152/384 (39.58%), Postives = 235/384 (61.20%), Query Frame = 1
Query: 169 NENILFVLTVFSVFTGLLAGFFIK-STFIVNEYQIYLISFPGEXXXXXXXXXXXXXXXXXXXXXXXXXETKSSGKIGLYTVLYYGITTSISLIMGMVLVVTIHPGN-PKIKNLQPLENTGPTSNIGALESIFDLIRNIFPPNLIEGCFRQVATNYAIEKENIYKNFT---EFPRNISKLTITMVESTNILGLVFFSITFGLILGQLGNKGKKMFQFFEVLNQVIMTMVTYIMWYFPXXXXXXXXXXXXXXXNLESAASSLGLYIMTVLLGLFIHGGIVLPLMYFIVCKKNPYWFFRALPQAWLASFGTASSTATLPITFKCLESNKLVSKKVTRFVLPIGATINMDGTALYEAVASIFIAQINGMVLSFGQIFSMSYICSNWSL 1305
EN+L + TV VF G L GF IK ST ++ +I ISFPGE+ + MLK LI+PLL SS+ + + L+ S KI + YY +TT ++I+G+ LV T+ PG KI Q E+ S + +++ DL+RN+F N+I+ Q + IY+N + P + E +N+LGLV FS+ G +G++ KG+ + FF L++ +MT+ ++++W P+G+ FLI KI+E++++ + SLG Y +TV++GLF+HG + +++F+ ++ PY + L Q +FGT SS+AT+P+T KCL+ N + +VTRFV+P+GATINMDGTALYEAVA++FIAQ M SFG I ++S + S+
Sbjct: 16 QENVLTMATVIGVFVGGLIGFIIKNSTGEWSKREIMYISFPGEIFLRMLKCLIVPLLVSSITSAIGGLDLSMSSKIATRAITYYFVTTISAVILGICLVTTLRPGQGAKIVETQT-ESIDKASKVLTPDTLMDLVRNMFTDNIIQSTMFQ-------HRTEIYENTSISPAQPMENWEFKSAQREGSNVLGLVMFSVILGTTIGRMREKGQLLQDFFTTLSEAMMTITSWVIWISPLGVAFLIAAKIIEMESIAATIQSLGWYFITVMIGLFLHGFGTIAVIFFLGTRRLPYRYIAKLSQVLATAFGTGSSSATMPLTIKCLD-NMGIDPRVTRFVIPVGATINMDGTALYEAVAALFIAQYREMSYSFGTIVAVSITATAASI 390 HSP 2 Score: 77.411 bits (189), Expect = 1.133e-73 Identity = 38/77 (49.35%), Postives = 56/77 (72.73%), Query Frame = 2
Query: 1280 ATFAAIGASCVPSSGLVTVIPALASVGLPISDITLILTVDWFLDRVRTTINVLGDSLGSGIIESLLENDKIEIDWIN 1510
AT A+IGA+ +P +GLVT++ L +VGL D++LI+ VDW LDR RTTINV+ D+LG+ ++ L +ND +D +N
Sbjct: 385 ATAASIGAAGIPQAGLVTMVMVLDTVGLEPKDVSLIIAVDWLLDRFRTTINVMCDALGTILVNHLSKNDLASVDRLN 461
BLAST of slc1a-4 vs. Ensembl Fly
Match: Eaat2 (gene:FBgn0026438 transcript:FBtr0301316) HSP 1 Score: 225.713 bits (574), Expect = 3.312e-68 Identity = 161/395 (40.76%), Postives = 243/395 (61.52%), Query Frame = 1
Query: 151 KKFLSNNENILFVLTVFSVFTGLLAGFFIKSTFIVNEYQIYLISFPGEXXXXXXXXXXXXXXXXXXXXXXXXXETKSSGKIGLYTVLYYGITTSISLIMGMVLVVTIHPGNPKIKNLQPLENTGPTSNIGALESIFDLIRNIFPPNLIEGCFRQVATNYAIEKENIYKNFTEFPRNI-------SKLTITMVES------------TNILGLVFFSITFGLILGQLGNKGKKMFQFFEVLNQVIMTMVTYIMWYFPXXXXXXXXXXXXXXXNLESAASSLGLYIMTVLLGLFIHGGIVLPLMYFIVCKKNPYWFFRALPQAWLASFGTASSTATLPITFKCLESNKLVSKKVTRFVLPIGATINMDGTALYEAVASIFIAQINGMVLSFGQIFSM 1278
+++LS EN++ ++T+ V G++ G ++ + + I LIS+PGE+ M +LK++ILPL+ SSLI G + L K +GKI L T++Y+ T+ + +G+ LV+ IHPGNP + N + + + L+S+ DL RN+FP NL + +Q T Y + K +I F E + +L+ + E TN LG+VFF + FG LG +G KG+ + FF + +VIM MVT +MW P+GI +I GKIL + +L S L +I+TV +G+FI+ +V+ +YF+V ++NP+ F+ L QA L +F TAS+ A LPITF+C+ V ++TRFVLPIG INMDGTALY AVASIFIAQ++GMVL FG++ ++
Sbjct: 43 RRWLS--ENLMLLVTLSGVLLGVILGLSLRPLNLHGD-SIMLISYPGELFMRVLKLMILPLVISSLIAGSASLNAKMNGKIALRTLVYFASTSFFNAALGIALVLLIHPGNPDLHNAD--DRSTDRRAVNLLDSLLDLGRNVFPDNLFQASIQQAHTVY-LPKPSILHVFNETMNDTLASGSEAQRLSEDLTEDVVLVRDIQYRSGTNTLGIVFFCLVFGTFLGTIGQKGQVVVDFFAAIFEVIMKMVTCVMWLTPVGISSVIAGKILSVGDLGLVMSQLMWFIVTVAIGVFIYQFVVMQAIYFVVVRRNPFKFYAGLIQAMLTAFATASTAAALPITFRCMNEKLKVDPRITRFVLPIGCNINMDGTALYIAVASIFIAQMSGMVLGFGELLTV 431 HSP 2 Score: 53.1434 bits (126), Expect = 3.312e-68 Identity = 22/55 (40.00%), Postives = 36/55 (65.45%), Query Frame = 2
Query: 1364 PISDITLILTVDWFLDRVRTTINVLGDSLGSGIIESLLENDKIEIDW--INNSDL 1522
P+ D+TL+ VDWF+DR+RTT N+LGD + ++E L + + +D +N D+
Sbjct: 463 PVQDVTLLFAVDWFVDRIRTTNNMLGDCYTAAVVEELSRKELMALDAASVNYQDM 517
BLAST of slc1a-4 vs. Ensembl Zebrafish
Match: slc1a2b (solute carrier family 1 member 2b [Source:ZFIN;Acc:ZDB-GENE-030131-7779]) HSP 1 Score: 303.908 bits (777), Expect = 5.162e-100 Identity = 183/386 (47.41%), Postives = 265/386 (68.65%), Query Frame = 1
Query: 169 NENILFVLTVFSVFTGLLAGFFIKSTFIVNEYQIYLISFPGEXXXXXXXXXXXXXXXXXXXXXXXXXETKSSGKIGLYTVLYYGITTSISLIMGMVLVVTIHPGNPKIK-NL-QPLENTGPTSNIGALESIFDLIRNIFPPNLIEGCFRQVAT-----NYAIEKENIYKNFTEFPRNISK--------LTITMVESTNILGLVFFSITFGLILGQLGNKGKKMFQFFEVLNQVIMTMVTYIMWYFPXXXXXXXXXXXXXXXNLESAASSLGLYIMTVLLGLFIHGGIVLPLMYFIVCKKNPYWFFRALPQAWLASFGTASSTATLPITFKCLESNKLVSKKVTRFVLPIGATINMDGTALYEAVASIFIAQINGMVLSFGQIFSMS 1281
+N+L LTV V G ++G ++ +++ + +I+FPG++LM MLKMLILPL+ SSLITGL+ L+ KSSG++G ++YY TT I+ ++G++LV+ IHPGNPK+K NL + LEN + +L++ FDLIRN+FP NL++ CF+Q+ T + ++ +E+ N +K ++ N+LGL+ F I FG+ +G++G K + M FF +LN+++M +V IMWY P GI LI GKI+ IK+LE A LG+Y++TV++GL IHG I LP +YF + +KNP+ FF + QAW+ + GTASS TLP+TF+CLE N + K+VTRFVLP+GATINMDGTALYEAVA+IFIAQ+NG+ L GQI ++S
Sbjct: 34 RKNLLLTLTVMGVIMGAVSGMLLRVASPIDDNIVMVIAFPGDILMRMLKMLILPLIISSLITGLAGLDAKSSGRLGSRAMIYYMTTTVIAAVLGVILVLLIHPGNPKLKENLGEGLEN----DEVSSLDAFFDLIRNLFPENLVQACFQQIQTVVKKVEVQPDLDDTNSTMSEYLSNATKPPPIFKDKKSLQFKSGMNVLGLIGFFIAFGICMGKMGEKARLMIDFFNILNEIVMKLVIMIMWYSPFGIACLICGKIISIKDLEVVARQLGMYMITVIVGLIIHGAIFLPCIYFAIVRKNPFSFFMGIFQAWITALGTASSAGTLPVTFRCLEENLGIDKRVTRFVLPVGATINMDGTALYEAVAAIFIAQMNGIDLDPGQIVTVS 415 HSP 2 Score: 81.6481 bits (200), Expect = 5.162e-100 Identity = 39/77 (50.65%), Postives = 58/77 (75.32%), Query Frame = 2
Query: 1280 ATFAAIGASCVPSSGLVTVIPALASVGLPISDITLILTVDWFLDRVRTTINVLGDSLGSGIIESLLENDKIEIDWIN 1510
AT A++GA+ +PS+GLVT++ L +VGLP DI+L++ VDW LDR RT++NV+GDS G+GI+ L K E+D ++
Sbjct: 418 ATLASVGAASIPSAGLVTMLLILTAVGLPTQDISLLVAVDWLLDRFRTSVNVVGDSYGAGIVYHL---SKAELDALD 491
BLAST of slc1a-4 vs. Ensembl Zebrafish
Match: slc1a2b (solute carrier family 1 member 2b [Source:ZFIN;Acc:ZDB-GENE-030131-7779]) HSP 1 Score: 303.523 bits (776), Expect = 5.992e-100 Identity = 183/386 (47.41%), Postives = 265/386 (68.65%), Query Frame = 1
Query: 169 NENILFVLTVFSVFTGLLAGFFIKSTFIVNEYQIYLISFPGEXXXXXXXXXXXXXXXXXXXXXXXXXETKSSGKIGLYTVLYYGITTSISLIMGMVLVVTIHPGNPKIK-NL-QPLENTGPTSNIGALESIFDLIRNIFPPNLIEGCFRQVAT-----NYAIEKENIYKNFTEFPRNISK--------LTITMVESTNILGLVFFSITFGLILGQLGNKGKKMFQFFEVLNQVIMTMVTYIMWYFPXXXXXXXXXXXXXXXNLESAASSLGLYIMTVLLGLFIHGGIVLPLMYFIVCKKNPYWFFRALPQAWLASFGTASSTATLPITFKCLESNKLVSKKVTRFVLPIGATINMDGTALYEAVASIFIAQINGMVLSFGQIFSMS 1281
+N+L LTV V G ++G ++ +++ + +I+FPG++LM MLKMLILPL+ SSLITGL+ L+ KSSG++G ++YY TT I+ ++G++LV+ IHPGNPK+K NL + LEN + +L++ FDLIRN+FP NL++ CF+Q+ T + ++ +E+ N +K ++ N+LGL+ F I FG+ +G++G K + M FF +LN+++M +V IMWY P GI LI GKI+ IK+LE A LG+Y++TV++GL IHG I LP +YF + +KNP+ FF + QAW+ + GTASS TLP+TF+CLE N + K+VTRFVLP+GATINMDGTALYEAVA+IFIAQ+NG+ L GQI ++S
Sbjct: 34 RKNLLLTLTVMGVIMGAVSGMLLRVASPIDDNIVMVIAFPGDILMRMLKMLILPLIISSLITGLAGLDAKSSGRLGSRAMIYYMTTTVIAAVLGVILVLLIHPGNPKLKENLGEGLEN----DEVSSLDAFFDLIRNLFPENLVQACFQQIQTVVKKVEVQPDLDDTNSTMSEYLSNATKPPPIFKDKKSLQFKSGMNVLGLIGFFIAFGICMGKMGEKARLMIDFFNILNEIVMKLVIMIMWYSPFGIACLICGKIISIKDLEVVARQLGMYMITVIVGLIIHGAIFLPCIYFAIVRKNPFSFFMGIFQAWITALGTASSAGTLPVTFRCLEENLGIDKRVTRFVLPVGATINMDGTALYEAVAAIFIAQMNGIDLDPGQIVTVS 415 HSP 2 Score: 81.6481 bits (200), Expect = 5.992e-100 Identity = 39/77 (50.65%), Postives = 58/77 (75.32%), Query Frame = 2
Query: 1280 ATFAAIGASCVPSSGLVTVIPALASVGLPISDITLILTVDWFLDRVRTTINVLGDSLGSGIIESLLENDKIEIDWIN 1510
AT A++GA+ +PS+GLVT++ L +VGLP DI+L++ VDW LDR RT++NV+GDS G+GI+ L K E+D ++
Sbjct: 418 ATLASVGAASIPSAGLVTMLLILTAVGLPTQDISLLVAVDWLLDRFRTSVNVVGDSYGAGIVYHL---SKAELDALD 491
BLAST of slc1a-4 vs. Ensembl Zebrafish
Match: slc1a2b (solute carrier family 1 member 2b [Source:ZFIN;Acc:ZDB-GENE-030131-7779]) HSP 1 Score: 303.523 bits (776), Expect = 6.195e-100 Identity = 183/386 (47.41%), Postives = 265/386 (68.65%), Query Frame = 1
Query: 169 NENILFVLTVFSVFTGLLAGFFIKSTFIVNEYQIYLISFPGEXXXXXXXXXXXXXXXXXXXXXXXXXETKSSGKIGLYTVLYYGITTSISLIMGMVLVVTIHPGNPKIK-NL-QPLENTGPTSNIGALESIFDLIRNIFPPNLIEGCFRQVAT-----NYAIEKENIYKNFTEFPRNISK--------LTITMVESTNILGLVFFSITFGLILGQLGNKGKKMFQFFEVLNQVIMTMVTYIMWYFPXXXXXXXXXXXXXXXNLESAASSLGLYIMTVLLGLFIHGGIVLPLMYFIVCKKNPYWFFRALPQAWLASFGTASSTATLPITFKCLESNKLVSKKVTRFVLPIGATINMDGTALYEAVASIFIAQINGMVLSFGQIFSMS 1281
+N+L LTV V G ++G ++ +++ + +I+FPG++LM MLKMLILPL+ SSLITGL+ L+ KSSG++G ++YY TT I+ ++G++LV+ IHPGNPK+K NL + LEN + +L++ FDLIRN+FP NL++ CF+Q+ T + ++ +E+ N +K ++ N+LGL+ F I FG+ +G++G K + M FF +LN+++M +V IMWY P GI LI GKI+ IK+LE A LG+Y++TV++GL IHG I LP +YF + +KNP+ FF + QAW+ + GTASS TLP+TF+CLE N + K+VTRFVLP+GATINMDGTALYEAVA+IFIAQ+NG+ L GQI ++S
Sbjct: 33 RKNLLLTLTVMGVIMGAVSGMLLRVASPIDDNIVMVIAFPGDILMRMLKMLILPLIISSLITGLAGLDAKSSGRLGSRAMIYYMTTTVIAAVLGVILVLLIHPGNPKLKENLGEGLEN----DEVSSLDAFFDLIRNLFPENLVQACFQQIQTVVKKVEVQPDLDDTNSTMSEYLSNATKPPPIFKDKKSLQFKSGMNVLGLIGFFIAFGICMGKMGEKARLMIDFFNILNEIVMKLVIMIMWYSPFGIACLICGKIISIKDLEVVARQLGMYMITVIVGLIIHGAIFLPCIYFAIVRKNPFSFFMGIFQAWITALGTASSAGTLPVTFRCLEENLGIDKRVTRFVLPVGATINMDGTALYEAVAAIFIAQMNGIDLDPGQIVTVS 414 HSP 2 Score: 81.6481 bits (200), Expect = 6.195e-100 Identity = 39/77 (50.65%), Postives = 58/77 (75.32%), Query Frame = 2
Query: 1280 ATFAAIGASCVPSSGLVTVIPALASVGLPISDITLILTVDWFLDRVRTTINVLGDSLGSGIIESLLENDKIEIDWIN 1510
AT A++GA+ +PS+GLVT++ L +VGLP DI+L++ VDW LDR RT++NV+GDS G+GI+ L K E+D ++
Sbjct: 417 ATLASVGAASIPSAGLVTMLLILTAVGLPTQDISLLVAVDWLLDRFRTSVNVVGDSYGAGIVYHL---SKAELDALD 490
BLAST of slc1a-4 vs. Ensembl Zebrafish
Match: slc1a2b (solute carrier family 1 member 2b [Source:ZFIN;Acc:ZDB-GENE-030131-7779]) HSP 1 Score: 303.523 bits (776), Expect = 6.959e-100 Identity = 183/386 (47.41%), Postives = 265/386 (68.65%), Query Frame = 1
Query: 169 NENILFVLTVFSVFTGLLAGFFIKSTFIVNEYQIYLISFPGEXXXXXXXXXXXXXXXXXXXXXXXXXETKSSGKIGLYTVLYYGITTSISLIMGMVLVVTIHPGNPKIK-NL-QPLENTGPTSNIGALESIFDLIRNIFPPNLIEGCFRQVAT-----NYAIEKENIYKNFTEFPRNISK--------LTITMVESTNILGLVFFSITFGLILGQLGNKGKKMFQFFEVLNQVIMTMVTYIMWYFPXXXXXXXXXXXXXXXNLESAASSLGLYIMTVLLGLFIHGGIVLPLMYFIVCKKNPYWFFRALPQAWLASFGTASSTATLPITFKCLESNKLVSKKVTRFVLPIGATINMDGTALYEAVASIFIAQINGMVLSFGQIFSMS 1281
+N+L LTV V G ++G ++ +++ + +I+FPG++LM MLKMLILPL+ SSLITGL+ L+ KSSG++G ++YY TT I+ ++G++LV+ IHPGNPK+K NL + LEN + +L++ FDLIRN+FP NL++ CF+Q+ T + ++ +E+ N +K ++ N+LGL+ F I FG+ +G++G K + M FF +LN+++M +V IMWY P GI LI GKI+ IK+LE A LG+Y++TV++GL IHG I LP +YF + +KNP+ FF + QAW+ + GTASS TLP+TF+CLE N + K+VTRFVLP+GATINMDGTALYEAVA+IFIAQ+NG+ L GQI ++S
Sbjct: 36 RKNLLLTLTVMGVIMGAVSGMLLRVASPIDDNIVMVIAFPGDILMRMLKMLILPLIISSLITGLAGLDAKSSGRLGSRAMIYYMTTTVIAAVLGVILVLLIHPGNPKLKENLGEGLEN----DEVSSLDAFFDLIRNLFPENLVQACFQQIQTVVKKVEVQPDLDDTNSTMSEYLSNATKPPPIFKDKKSLQFKSGMNVLGLIGFFIAFGICMGKMGEKARLMIDFFNILNEIVMKLVIMIMWYSPFGIACLICGKIISIKDLEVVARQLGMYMITVIVGLIIHGAIFLPCIYFAIVRKNPFSFFMGIFQAWITALGTASSAGTLPVTFRCLEENLGIDKRVTRFVLPVGATINMDGTALYEAVAAIFIAQMNGIDLDPGQIVTVS 417 HSP 2 Score: 81.6481 bits (200), Expect = 6.959e-100 Identity = 39/74 (52.70%), Postives = 56/74 (75.68%), Query Frame = 2
Query: 1280 ATFAAIGASCVPSSGLVTVIPALASVGLPISDITLILTVDWFLDRVRTTINVLGDSLGSGIIESLLENDKIEID 1501
AT A++GA+ +PS+GLVT++ L +VGLP DI+L++ VDW LDR RT++NV+GDS G+GI+ L K E+D
Sbjct: 420 ATLASVGAASIPSAGLVTMLLILTAVGLPTQDISLLVAVDWLLDRFRTSVNVVGDSYGAGIVYHL---SKAELD 490
BLAST of slc1a-4 vs. Ensembl Zebrafish
Match: slc1a3b (solute carrier family 1 member 3b [Source:ZFIN;Acc:ZDB-GENE-090708-3]) HSP 1 Score: 290.041 bits (741), Expect = 1.098e-98 Identity = 185/411 (45.01%), Postives = 273/411 (66.42%), Query Frame = 1
Query: 118 KRSNTMRKIHLKKFLSNNENILFVLTVFSVFTGLLAGFFIKSTFIVNEYQIYLISFPGEXXXXXXXXXXXXXXXXXXXXXXXXXETKSSGKIGLYTVLYYGITTSISLIMGMVLVVTIHPGN---PKIKNLQPLENTGPTSNIGALESIFDLIRNIFPPNLIEGCFRQVATNYA--------IEKENIYKNFTEFPRNISKLTITMVEST----NILGLVFFSITFGLILGQLGNKGKKMFQFFEVLNQVIMTMVTYIMWYFPXXXXXXXXXXXXXXXNLESAASSLGLYIMTVLLGLFIHGGIVLPLMYFIVCKKNPYWFFRALPQAWLASFGTASSTATLPITFKCLESNKLVSKKVTRFVLPIGATINMDGTALYEAVASIFIAQINGMVLSFGQIFSMSYICSNWSL 1305
K+ + K +K FL N +LF T+ +V G+ GF ++S + ++ ++ SFPGE+LM ML+ML+LPLL SSLITG++ L++++SGK+G+ V+YY TT I++ +G+++V+ IHPG + Q +E P ++ DLIRN+FPPNL++ C +Q T Y I ++I+ N T + I++ + + T N LGLV FS+ FGLI+G + +G+ + FF+ LN+ IM +V IMWY PIGI FLI GKI+E+ ++ + LG+Y +TV++GL IHG I+LP +YF++ +KNP+ F L QA + + GT+SS+ATLPITFKCLE N V K+VTRFVLP+GATINMDGTALYEA+A+IFIAQ+N M ++FGQI ++S + S+
Sbjct: 31 KKVEDISKDDVKGFLRRNAFVLF--TIGAVVFGITLGFALRS-YKMSYREVKYFSFPGELLMRMLQMLVLPLLVSSLITGMAALDSRASGKMGMRAVIYYMTTTFIAVFIGIIMVLIIHPGKGSKDEFTKQQKIEQVSPA------DAFLDLIRNMFPPNLVQACTQQFKTQYGKRIIHVKMIVNDSIF-NLTNATQEIAQEEVIPLSGTTNGVNALGLVVFSMCFGLIIGNMKEQGQALRDFFDSLNEAIMRLVAIIMWYAPIGILFLIAGKIVEMDDITAMGGQLGMYTVTVIIGLMIHGIIILPTLYFVITRKNPFIFITGLLQALITALGTSSSSATLPITFKCLEENNKVDKRVTRFVLPVGATINMDGTALYEALAAIFIAQVNNMEMNFGQIITISITATAASI 431 HSP 2 Score: 91.2781 bits (225), Expect = 1.098e-98 Identity = 45/72 (62.50%), Postives = 58/72 (80.56%), Query Frame = 2
Query: 1280 ATFAAIGASCVPSSGLVTVIPALASVGLPISDITLILTVDWFLDRVRTTINVLGDSLGSGIIESLLENDKIE 1495
AT A+IGA+ +P +GLVT++ L SVGLP DITLI+ VDWFLDR+RTT NVLGDS+G+GIIE L D+++
Sbjct: 426 ATAASIGAAGIPQAGLVTMVIVLTSVGLPTDDITLIIAVDWFLDRLRTTTNVLGDSIGAGIIE-FLSKDELQ 496
BLAST of slc1a-4 vs. Ensembl Xenopus
Match: SLC1A2 (solute carrier family 1 member 2 [Source:NCBI gene;Acc:100494868]) HSP 1 Score: 306.22 bits (783), Expect = 1.084e-100 Identity = 180/387 (46.51%), Postives = 267/387 (68.99%), Query Frame = 1
Query: 175 NILFVLTVFSVFTGLLAGFFIKSTFIVNEYQIYLISFPGEXXXXXXXXXXXXXXXXXXXXXXXXXETKSSGKIGLYTVLYYGITTSISLIMGMVLVVTIHPGNPKIKNLQPLENTGPTSNIGALESIFDLIRNIFPPNLIEGCFRQVATNYAIEKENIYKNFTEFPRNISKLTITMVEST------------------NILGLVFFSITFGLILGQLGNKGKKMFQFFEVLNQVIMTMVTYIMWYFPXXXXXXXXXXXXXXXNLESAASSLGLYIMTVLLGLFIHGGIVLPLMYFIVCKKNPYWFFRALPQAWLASFGTASSTATLPITFKCLESNKLVSKKVTRFVLPIGATINMDGTALYEAVASIFIAQINGMVLSFGQIFSMS 1281
N+L LTVF V G ++G ++ ++ + +I+FPG++LM MLKMLILPL+ SSLITGL+ L+ KSSG++G ++YY TT I+ I+G++LV+ IHPG+PK+K + L + +L++ DLIRN+FP NL++ CF+Q+ T + K+ + + TE P N++ ++ T N+LG++ F I FG+ +G++G + + M +FF +LN+++M +VT IMWY P+GI LI GKI+ IK+LE A LG+Y++TV++GL IHG I LPL+YF++ +K+P+ F + QAW+ + GTASS TLP+TF+CLE N + K+VTRFVLP+GATINMDGTALYEAVA+IFIAQ+NG++L GQI ++S
Sbjct: 44 NLLLSLTVFGVIMGAVSGGLLRMASPIHPDIVMVIAFPGDILMRMLKMLILPLIISSLITGLAGLDAKSSGRLGTRAMIYYMSTTIIAAILGVILVLAIHPGDPKLK--KQLGKGQENDEVSSLDAFLDLIRNLFPENLVQACFQQIQT---VTKKVVVEAPTEEPSNVTDSVFALMNDTVATTTEEIRKKLEFKDGMNVLGVIGFFIAFGIAMGKMGEQARLMVEFFNILNEIVMKLVTMIMWYSPLGIACLICGKIIAIKDLELVARQLGMYMVTVIVGLIIHGAIFLPLLYFVITRKSPFTFLAGVFQAWITALGTASSAGTLPVTFRCLEENLGIDKRVTRFVLPVGATINMDGTALYEAVAAIFIAQMNGVILDGGQIITVS 425 HSP 2 Score: 82.4185 bits (202), Expect = 1.084e-100 Identity = 38/80 (47.50%), Postives = 59/80 (73.75%), Query Frame = 2
Query: 1280 ATFAAIGASCVPSSGLVTVIPALASVGLPISDITLILTVDWFLDRVRTTINVLGDSLGSGIIESLLENDKIEIDWINNSD 1519
AT A++GA+ +PS+GLVT++ L +VGLP DI+L++ VDW LDR+RT++NV+GDS G+GI+ L K E++ ++
Sbjct: 428 ATLASVGAASIPSAGLVTMLLILTAVGLPTQDISLLVAVDWLLDRMRTSVNVVGDSFGAGIVYHL---SKAELESLDKQH 504
BLAST of slc1a-4 vs. Ensembl Xenopus
Match: SLC1A2 (solute carrier family 1 member 2 [Source:NCBI gene;Acc:100494868]) HSP 1 Score: 306.22 bits (783), Expect = 1.159e-100 Identity = 180/387 (46.51%), Postives = 267/387 (68.99%), Query Frame = 1
Query: 175 NILFVLTVFSVFTGLLAGFFIKSTFIVNEYQIYLISFPGEXXXXXXXXXXXXXXXXXXXXXXXXXETKSSGKIGLYTVLYYGITTSISLIMGMVLVVTIHPGNPKIKNLQPLENTGPTSNIGALESIFDLIRNIFPPNLIEGCFRQVATNYAIEKENIYKNFTEFPRNISKLTITMVEST------------------NILGLVFFSITFGLILGQLGNKGKKMFQFFEVLNQVIMTMVTYIMWYFPXXXXXXXXXXXXXXXNLESAASSLGLYIMTVLLGLFIHGGIVLPLMYFIVCKKNPYWFFRALPQAWLASFGTASSTATLPITFKCLESNKLVSKKVTRFVLPIGATINMDGTALYEAVASIFIAQINGMVLSFGQIFSMS 1281
N+L LTVF V G ++G ++ ++ + +I+FPG++LM MLKMLILPL+ SSLITGL+ L+ KSSG++G ++YY TT I+ I+G++LV+ IHPG+PK+K + L + +L++ DLIRN+FP NL++ CF+Q+ T + K+ + + TE P N++ ++ T N+LG++ F I FG+ +G++G + + M +FF +LN+++M +VT IMWY P+GI LI GKI+ IK+LE A LG+Y++TV++GL IHG I LPL+YF++ +K+P+ F + QAW+ + GTASS TLP+TF+CLE N + K+VTRFVLP+GATINMDGTALYEAVA+IFIAQ+NG++L GQI ++S
Sbjct: 48 NLLLSLTVFGVIMGAVSGGLLRMASPIHPDIVMVIAFPGDILMRMLKMLILPLIISSLITGLAGLDAKSSGRLGTRAMIYYMSTTIIAAILGVILVLAIHPGDPKLK--KQLGKGQENDEVSSLDAFLDLIRNLFPENLVQACFQQIQT---VTKKVVVEAPTEEPSNVTDSVFALMNDTVATTTEEIRKKLEFKDGMNVLGVIGFFIAFGIAMGKMGEQARLMVEFFNILNEIVMKLVTMIMWYSPLGIACLICGKIIAIKDLELVARQLGMYMVTVIVGLIIHGAIFLPLLYFVITRKSPFTFLAGVFQAWITALGTASSAGTLPVTFRCLEENLGIDKRVTRFVLPVGATINMDGTALYEAVAAIFIAQMNGVILDGGQIITVS 429 HSP 2 Score: 82.0333 bits (201), Expect = 1.159e-100 Identity = 38/80 (47.50%), Postives = 59/80 (73.75%), Query Frame = 2
Query: 1280 ATFAAIGASCVPSSGLVTVIPALASVGLPISDITLILTVDWFLDRVRTTINVLGDSLGSGIIESLLENDKIEIDWINNSD 1519
AT A++GA+ +PS+GLVT++ L +VGLP DI+L++ VDW LDR+RT++NV+GDS G+GI+ L K E++ ++
Sbjct: 432 ATLASVGAASIPSAGLVTMLLILTAVGLPTQDISLLVAVDWLLDRMRTSVNVVGDSFGAGIVYHL---SKAELESLDKQH 508
BLAST of slc1a-4 vs. Ensembl Xenopus
Match: SLC1A2 (solute carrier family 1 member 2 [Source:NCBI gene;Acc:100494868]) HSP 1 Score: 305.834 bits (782), Expect = 1.228e-100 Identity = 180/387 (46.51%), Postives = 267/387 (68.99%), Query Frame = 1
Query: 175 NILFVLTVFSVFTGLLAGFFIKSTFIVNEYQIYLISFPGEXXXXXXXXXXXXXXXXXXXXXXXXXETKSSGKIGLYTVLYYGITTSISLIMGMVLVVTIHPGNPKIKNLQPLENTGPTSNIGALESIFDLIRNIFPPNLIEGCFRQVATNYAIEKENIYKNFTEFPRNISKLTITMVEST------------------NILGLVFFSITFGLILGQLGNKGKKMFQFFEVLNQVIMTMVTYIMWYFPXXXXXXXXXXXXXXXNLESAASSLGLYIMTVLLGLFIHGGIVLPLMYFIVCKKNPYWFFRALPQAWLASFGTASSTATLPITFKCLESNKLVSKKVTRFVLPIGATINMDGTALYEAVASIFIAQINGMVLSFGQIFSMS 1281
N+L LTVF V G ++G ++ ++ + +I+FPG++LM MLKMLILPL+ SSLITGL+ L+ KSSG++G ++YY TT I+ I+G++LV+ IHPG+PK+K + L + +L++ DLIRN+FP NL++ CF+Q+ T + K+ + + TE P N++ ++ T N+LG++ F I FG+ +G++G + + M +FF +LN+++M +VT IMWY P+GI LI GKI+ IK+LE A LG+Y++TV++GL IHG I LPL+YF++ +K+P+ F + QAW+ + GTASS TLP+TF+CLE N + K+VTRFVLP+GATINMDGTALYEAVA+IFIAQ+NG++L GQI ++S
Sbjct: 44 NLLLSLTVFGVIMGAVSGGLLRMASPIHPDIVMVIAFPGDILMRMLKMLILPLIISSLITGLAGLDAKSSGRLGTRAMIYYMSTTIIAAILGVILVLAIHPGDPKLK--KQLGKGQENDEVSSLDAFLDLIRNLFPENLVQACFQQIQT---VTKKVVVEAPTEEPSNVTDSVFALMNDTVATTTEEIRKKLEFKDGMNVLGVIGFFIAFGIAMGKMGEQARLMVEFFNILNEIVMKLVTMIMWYSPLGIACLICGKIIAIKDLELVARQLGMYMVTVIVGLIIHGAIFLPLLYFVITRKSPFTFLAGVFQAWITALGTASSAGTLPVTFRCLEENLGIDKRVTRFVLPVGATINMDGTALYEAVAAIFIAQMNGVILDGGQIITVS 425 HSP 2 Score: 82.4185 bits (202), Expect = 1.228e-100 Identity = 38/80 (47.50%), Postives = 59/80 (73.75%), Query Frame = 2
Query: 1280 ATFAAIGASCVPSSGLVTVIPALASVGLPISDITLILTVDWFLDRVRTTINVLGDSLGSGIIESLLENDKIEIDWINNSD 1519
AT A++GA+ +PS+GLVT++ L +VGLP DI+L++ VDW LDR+RT++NV+GDS G+GI+ L K E++ ++
Sbjct: 428 ATLASVGAASIPSAGLVTMLLILTAVGLPTQDISLLVAVDWLLDRMRTSVNVVGDSFGAGIVYHL---SKAELESLDKQH 504
BLAST of slc1a-4 vs. Ensembl Xenopus
Match: SLC1A2 (solute carrier family 1 member 2 [Source:NCBI gene;Acc:100494868]) HSP 1 Score: 306.22 bits (783), Expect = 1.249e-100 Identity = 180/387 (46.51%), Postives = 267/387 (68.99%), Query Frame = 1
Query: 175 NILFVLTVFSVFTGLLAGFFIKSTFIVNEYQIYLISFPGEXXXXXXXXXXXXXXXXXXXXXXXXXETKSSGKIGLYTVLYYGITTSISLIMGMVLVVTIHPGNPKIKNLQPLENTGPTSNIGALESIFDLIRNIFPPNLIEGCFRQVATNYAIEKENIYKNFTEFPRNISKLTITMVEST------------------NILGLVFFSITFGLILGQLGNKGKKMFQFFEVLNQVIMTMVTYIMWYFPXXXXXXXXXXXXXXXNLESAASSLGLYIMTVLLGLFIHGGIVLPLMYFIVCKKNPYWFFRALPQAWLASFGTASSTATLPITFKCLESNKLVSKKVTRFVLPIGATINMDGTALYEAVASIFIAQINGMVLSFGQIFSMS 1281
N+L LTVF V G ++G ++ ++ + +I+FPG++LM MLKMLILPL+ SSLITGL+ L+ KSSG++G ++YY TT I+ I+G++LV+ IHPG+PK+K + L + +L++ DLIRN+FP NL++ CF+Q+ T + K+ + + TE P N++ ++ T N+LG++ F I FG+ +G++G + + M +FF +LN+++M +VT IMWY P+GI LI GKI+ IK+LE A LG+Y++TV++GL IHG I LPL+YF++ +K+P+ F + QAW+ + GTASS TLP+TF+CLE N + K+VTRFVLP+GATINMDGTALYEAVA+IFIAQ+NG++L GQI ++S
Sbjct: 44 NLLLSLTVFGVIMGAVSGGLLRMASPIHPDIVMVIAFPGDILMRMLKMLILPLIISSLITGLAGLDAKSSGRLGTRAMIYYMSTTIIAAILGVILVLAIHPGDPKLK--KQLGKGQENDEVSSLDAFLDLIRNLFPENLVQACFQQIQT---VTKKVVVEAPTEEPSNVTDSVFALMNDTVATTTEEIRKKLEFKDGMNVLGVIGFFIAFGIAMGKMGEQARLMVEFFNILNEIVMKLVTMIMWYSPLGIACLICGKIIAIKDLELVARQLGMYMVTVIVGLIIHGAIFLPLLYFVITRKSPFTFLAGVFQAWITALGTASSAGTLPVTFRCLEENLGIDKRVTRFVLPVGATINMDGTALYEAVAAIFIAQMNGVILDGGQIITVS 425 HSP 2 Score: 82.0333 bits (201), Expect = 1.249e-100 Identity = 38/80 (47.50%), Postives = 59/80 (73.75%), Query Frame = 2
Query: 1280 ATFAAIGASCVPSSGLVTVIPALASVGLPISDITLILTVDWFLDRVRTTINVLGDSLGSGIIESLLENDKIEIDWINNSD 1519
AT A++GA+ +PS+GLVT++ L +VGLP DI+L++ VDW LDR+RT++NV+GDS G+GI+ L K E++ ++
Sbjct: 428 ATLASVGAASIPSAGLVTMLLILTAVGLPTQDISLLVAVDWLLDRMRTSVNVVGDSFGAGIVYHL---SKAELESLDKQH 504
BLAST of slc1a-4 vs. Ensembl Xenopus
Match: sugp1 (SURP and G-patch domain containing 1 [Source:Xenbase;Acc:XB-GENE-495007]) HSP 1 Score: 294.664 bits (753), Expect = 3.115e-100 Identity = 188/398 (47.24%), Postives = 266/398 (66.83%), Query Frame = 1
Query: 169 NENILFVLTVFSVFTGLLAGFFIKSTFIVNEYQIYLISFPGEXXXXXXXXXXXXXXXXXXXXXXXXXETKSSGKIGLYTVLYYGITTSISLIMGMVLVVTIHPGNPKIKNLQPLENTGPTSNIGALESIFDLIRNIFPPNLIEGCFRQVATNY-------AIEKENIYKNFTEFPRNISKLTITMVE------------STNILGLVFFSITFGLILGQLGNKGKKMFQFFEVLNQVIMTMVTYIMWYFPXXXXXXXXXXXXXXXNLESAASSLGLYIMTVLLGLFIHGGIVLPLMYFIVCKKNPYWFFRALPQAWLASFGTASSTATLPITFKCLESNKLVSKKVTRFVLPIGATINMDGTALYEAVASIFIAQINGMVLSFGQIFSMSYICSNWSL 1305
N +LT+ +V G++ F ++ + ++ QI SFPGE+LM ML+ML+LPL+ SSL+TG++ L++K+SGK+GL V+YY +TT I++ +G+V+V+ IHPG +NLQ + G + A ++I DLIRN+FPPNL+E CF+Q T Y + + Y TE NIS + MVE N LGLV FS+ FGL++G + +G+ + +FF+ LN+ IM +V I+WY PIGI FLI GKILE+ +L LG+Y +TV++GL IH +VLPL++FIV ++NP+ F L QA + + GT+SS+ATLPITFKCLE N V K+VTRFVLP+GATINMDGTALYEA+A+IFIAQ+N L+FGQI ++S + S+
Sbjct: 58 RRNAFVILTIAAVILGIVLAFALRP-YKMSYRQIKYFSFPGELLMRMLQMLVLPLIVSSLVTGMASLDSKASGKMGLRAVVYYTVTTFIAVFIGIVMVIIIHPGKGTKENLQ---SHGKIERVQATDAILDLIRNMFPPNLVEACFKQYKTQYNTRVYKVPVSTDQNYSIATE-QLNISSILENMVELEEVVPIAGSAGGVNALGLVVFSMCFGLVIGNMKEQGRALKEFFDCLNEAIMRLVAIIIWYAPIGILFLISGKILEMDDLLVMGGQLGMYTITVIVGLLIHAVVVLPLLFFIVTRRNPWPFIGGLLQALITALGTSSSSATLPITFKCLEENNGVDKRVTRFVLPVGATINMDGTALYEALAAIFIAQVNNYELNFGQIITISITATAASI 450 HSP 2 Score: 92.0485 bits (227), Expect = 3.115e-100 Identity = 44/69 (63.77%), Postives = 56/69 (81.16%), Query Frame = 2
Query: 1280 ATFAAIGASCVPSSGLVTVIPALASVGLPISDITLILTVDWFLDRVRTTINVLGDSLGSGIIESLLEND 1486
AT A+IGA+ +P +GLVT++ L SVGLP DITLI+ VDWFLDR+RTT NVLGDSLG+GI+E L ++
Sbjct: 445 ATAASIGAAGIPQAGLVTMVIVLTSVGLPTEDITLIIAVDWFLDRLRTTTNVLGDSLGAGIVEHLSRHE 513
BLAST of slc1a-4 vs. Ensembl Mouse
Match: Slc1a2 (solute carrier family 1 (glial high affinity glutamate transporter), member 2 [Source:MGI Symbol;Acc:MGI:101931]) HSP 1 Score: 306.22 bits (783), Expect = 1.686e-101 Identity = 188/395 (47.59%), Postives = 269/395 (68.10%), Query Frame = 1
Query: 172 ENILFVLTVFSVFTGLLAGFFIKSTFIVNEYQIYLISFPGEXXXXXXXXXXXXXXXXXXXXXXXXXETKSSGKIGLYTVLYYGITTSISLIMGMVLVVTIHPGNPKIKNLQPLENTGP---TSNIGALESIFDLIRNIFPPNLIEGCFRQVATNYAIEKENIYKNFTEFPRNISKLTITMVEST----------------------NILGLVFFSITFGLILGQLGNKGKKMFQFFEVLNQVIMTMVTYIMWYFPXXXXXXXXXXXXXXXNLESAASSLGLYIMTVLLGLFIHGGIVLPLMYFIVCKKNPYWFFRALPQAWLASFGTASSTATLPITFKCLESNKLVSKKVTRFVLPIGATINMDGTALYEAVASIFIAQINGMVLSFGQIFSMS 1281
+N+L LTVF V G + G ++ ++ + LI+FPG++LM MLKMLILPL+ SSLITGLS L+ K+SG++G ++YY TT I+ ++G++LV+ IHPGNPK+K + GP + +L++ DLIRN+FP NL++ CF+Q+ T + K+ + +E N +K I+M+ T N+LGL+ F I FG+ +G++G + K M +FF +LN+++M +V IMWY P+GI LI GKI+ IK+LE A LG+Y++TV++GL IHGGI LPL+YF+V +KNP+ FF + QAW+ + GTASS TLP+TF+CLE N + K+VTRFVLP+GATINMDGTALYEAVA+IFIAQ+NG++L GQI ++S
Sbjct: 40 KNLLLSLTVFGVILGAVCGGLLRLASPIHPDVVMLIAFPGDILMRMLKMLILPLIISSLITGLSGLDAKASGRLGTRAMVYYMSTTIIAAVLGVILVLAIHPGNPKLK-----KQLGPGKKNDEVSSLDAFLDLIRNLFPENLVQACFQQIQT---VTKKVLVAPPSE-EANTTKAVISMLNETMNEAPEETKIVIKKGLEFKDGMNVLGLIGFFIAFGIAMGKMGEQAKLMVEFFNILNEIVMKLVIMIMWYSPLGIACLICGKIIAIKDLEVVARQLGMYMITVIVGLIIHGGIFLPLIYFVVTRKNPFSFFAGIFQAWITALGTASSAGTLPVTFRCLEDNLGIDKRVTRFVLPVGATINMDGTALYEAVAAIFIAQMNGVILDGGQIVTVS 425 HSP 2 Score: 84.3445 bits (207), Expect = 1.686e-101 Identity = 41/80 (51.25%), Postives = 60/80 (75.00%), Query Frame = 2
Query: 1280 ATFAAIGASCVPSSGLVTVIPALASVGLPISDITLILTVDWFLDRVRTTINVLGDSLGSGIIESLLENDKIEIDWINNSD 1519
AT A+IGA+ +PS+GLVT++ L +VGLP DI+L++ VDW LDR+RT++NV+GDS G+GI+ L K E+D I++
Sbjct: 428 ATLASIGAASIPSAGLVTMLLILTAVGLPTEDISLLVAVDWLLDRMRTSVNVVGDSFGAGIVYHL---SKSELDTIDSQH 504
BLAST of slc1a-4 vs. Ensembl Mouse
Match: Slc1a2 (solute carrier family 1 (glial high affinity glutamate transporter), member 2 [Source:MGI Symbol;Acc:MGI:101931]) HSP 1 Score: 306.22 bits (783), Expect = 1.910e-101 Identity = 189/407 (46.44%), Postives = 273/407 (67.08%), Query Frame = 1
Query: 136 RKIHLKKFLSNNENILFVLTVFSVFTGLLAGFFIKSTFIVNEYQIYLISFPGEXXXXXXXXXXXXXXXXXXXXXXXXXETKSSGKIGLYTVLYYGITTSISLIMGMVLVVTIHPGNPKIKNLQPLENTGP---TSNIGALESIFDLIRNIFPPNLIEGCFRQVATNYAIEKENIYKNFTEFPRNISKLTITMVEST----------------------NILGLVFFSITFGLILGQLGNKGKKMFQFFEVLNQVIMTMVTYIMWYFPXXXXXXXXXXXXXXXNLESAASSLGLYIMTVLLGLFIHGGIVLPLMYFIVCKKNPYWFFRALPQAWLASFGTASSTATLPITFKCLESNKLVSKKVTRFVLPIGATINMDGTALYEAVASIFIAQINGMVLSFGQIFSMS 1281
R + ++ +N+L LTVF V G + G ++ ++ + LI+FPG++LM MLKMLILPL+ SSLITGLS L+ K+SG++G ++YY TT I+ ++G++LV+ IHPGNPK+K + GP + +L++ DLIRN+FP NL++ CF+Q+ T + K+ + +E N +K I+M+ T N+LGL+ F I FG+ +G++G + K M +FF +LN+++M +V IMWY P+GI LI GKI+ IK+LE A LG+Y++TV++GL IHGGI LPL+YF+V +KNP+ FF + QAW+ + GTASS TLP+TF+CLE N + K+VTRFVLP+GATINMDGTALYEAVA+IFIAQ+NG++L GQI ++S
Sbjct: 28 RNLGMRMCDKLGKNLLLSLTVFGVILGAVCGGLLRLASPIHPDVVMLIAFPGDILMRMLKMLILPLIISSLITGLSGLDAKASGRLGTRAMVYYMSTTIIAAVLGVILVLAIHPGNPKLK-----KQLGPGKKNDEVSSLDAFLDLIRNLFPENLVQACFQQIQT---VTKKVLVAPPSE-EANTTKAVISMLNETMNEAPEETKIVIKKGLEFKDGMNVLGLIGFFIAFGIAMGKMGEQAKLMVEFFNILNEIVMKLVIMIMWYSPLGIACLICGKIIAIKDLEVVARQLGMYMITVIVGLIIHGGIFLPLIYFVVTRKNPFSFFAGIFQAWITALGTASSAGTLPVTFRCLEDNLGIDKRVTRFVLPVGATINMDGTALYEAVAAIFIAQMNGVILDGGQIVTVS 425 HSP 2 Score: 84.3445 bits (207), Expect = 1.910e-101 Identity = 41/80 (51.25%), Postives = 60/80 (75.00%), Query Frame = 2
Query: 1280 ATFAAIGASCVPSSGLVTVIPALASVGLPISDITLILTVDWFLDRVRTTINVLGDSLGSGIIESLLENDKIEIDWINNSD 1519
AT A+IGA+ +PS+GLVT++ L +VGLP DI+L++ VDW LDR+RT++NV+GDS G+GI+ L K E+D I++
Sbjct: 428 ATLASIGAASIPSAGLVTMLLILTAVGLPTEDISLLVAVDWLLDRMRTSVNVVGDSFGAGIVYHL---SKSELDTIDSQH 504
BLAST of slc1a-4 vs. Ensembl Mouse
Match: Slc1a2 (solute carrier family 1 (glial high affinity glutamate transporter), member 2 [Source:MGI Symbol;Acc:MGI:101931]) HSP 1 Score: 305.834 bits (782), Expect = 2.127e-101 Identity = 189/407 (46.44%), Postives = 273/407 (67.08%), Query Frame = 1
Query: 136 RKIHLKKFLSNNENILFVLTVFSVFTGLLAGFFIKSTFIVNEYQIYLISFPGEXXXXXXXXXXXXXXXXXXXXXXXXXETKSSGKIGLYTVLYYGITTSISLIMGMVLVVTIHPGNPKIKNLQPLENTGP---TSNIGALESIFDLIRNIFPPNLIEGCFRQVATNYAIEKENIYKNFTEFPRNISKLTITMVEST----------------------NILGLVFFSITFGLILGQLGNKGKKMFQFFEVLNQVIMTMVTYIMWYFPXXXXXXXXXXXXXXXNLESAASSLGLYIMTVLLGLFIHGGIVLPLMYFIVCKKNPYWFFRALPQAWLASFGTASSTATLPITFKCLESNKLVSKKVTRFVLPIGATINMDGTALYEAVASIFIAQINGMVLSFGQIFSMS 1281
R + ++ +N+L LTVF V G + G ++ ++ + LI+FPG++LM MLKMLILPL+ SSLITGLS L+ K+SG++G ++YY TT I+ ++G++LV+ IHPGNPK+K + GP + +L++ DLIRN+FP NL++ CF+Q+ T + K+ + +E N +K I+M+ T N+LGL+ F I FG+ +G++G + K M +FF +LN+++M +V IMWY P+GI LI GKI+ IK+LE A LG+Y++TV++GL IHGGI LPL+YF+V +KNP+ FF + QAW+ + GTASS TLP+TF+CLE N + K+VTRFVLP+GATINMDGTALYEAVA+IFIAQ+NG++L GQI ++S
Sbjct: 31 RNLGMRMCDKLGKNLLLSLTVFGVILGAVCGGLLRLASPIHPDVVMLIAFPGDILMRMLKMLILPLIISSLITGLSGLDAKASGRLGTRAMVYYMSTTIIAAVLGVILVLAIHPGNPKLK-----KQLGPGKKNDEVSSLDAFLDLIRNLFPENLVQACFQQIQT---VTKKVLVAPPSE-EANTTKAVISMLNETMNEAPEETKIVIKKGLEFKDGMNVLGLIGFFIAFGIAMGKMGEQAKLMVEFFNILNEIVMKLVIMIMWYSPLGIACLICGKIIAIKDLEVVARQLGMYMITVIVGLIIHGGIFLPLIYFVVTRKNPFSFFAGIFQAWITALGTASSAGTLPVTFRCLEDNLGIDKRVTRFVLPVGATINMDGTALYEAVAAIFIAQMNGVILDGGQIVTVS 428 HSP 2 Score: 84.3445 bits (207), Expect = 2.127e-101 Identity = 41/80 (51.25%), Postives = 60/80 (75.00%), Query Frame = 2
Query: 1280 ATFAAIGASCVPSSGLVTVIPALASVGLPISDITLILTVDWFLDRVRTTINVLGDSLGSGIIESLLENDKIEIDWINNSD 1519
AT A+IGA+ +PS+GLVT++ L +VGLP DI+L++ VDW LDR+RT++NV+GDS G+GI+ L K E+D I++
Sbjct: 431 ATLASIGAASIPSAGLVTMLLILTAVGLPTEDISLLVAVDWLLDRMRTSVNVVGDSFGAGIVYHL---SKSELDTIDSQH 507
BLAST of slc1a-4 vs. Ensembl Mouse
Match: Slc1a2 (solute carrier family 1 (glial high affinity glutamate transporter), member 2 [Source:MGI Symbol;Acc:MGI:101931]) HSP 1 Score: 305.834 bits (782), Expect = 2.312e-101 Identity = 188/395 (47.59%), Postives = 269/395 (68.10%), Query Frame = 1
Query: 172 ENILFVLTVFSVFTGLLAGFFIKSTFIVNEYQIYLISFPGEXXXXXXXXXXXXXXXXXXXXXXXXXETKSSGKIGLYTVLYYGITTSISLIMGMVLVVTIHPGNPKIKNLQPLENTGP---TSNIGALESIFDLIRNIFPPNLIEGCFRQVATNYAIEKENIYKNFTEFPRNISKLTITMVEST----------------------NILGLVFFSITFGLILGQLGNKGKKMFQFFEVLNQVIMTMVTYIMWYFPXXXXXXXXXXXXXXXNLESAASSLGLYIMTVLLGLFIHGGIVLPLMYFIVCKKNPYWFFRALPQAWLASFGTASSTATLPITFKCLESNKLVSKKVTRFVLPIGATINMDGTALYEAVASIFIAQINGMVLSFGQIFSMS 1281
+N+L LTVF V G + G ++ ++ + LI+FPG++LM MLKMLILPL+ SSLITGLS L+ K+SG++G ++YY TT I+ ++G++LV+ IHPGNPK+K + GP + +L++ DLIRN+FP NL++ CF+Q+ T + K+ + +E N +K I+M+ T N+LGL+ F I FG+ +G++G + K M +FF +LN+++M +V IMWY P+GI LI GKI+ IK+LE A LG+Y++TV++GL IHGGI LPL+YF+V +KNP+ FF + QAW+ + GTASS TLP+TF+CLE N + K+VTRFVLP+GATINMDGTALYEAVA+IFIAQ+NG++L GQI ++S
Sbjct: 43 KNLLLSLTVFGVILGAVCGGLLRLASPIHPDVVMLIAFPGDILMRMLKMLILPLIISSLITGLSGLDAKASGRLGTRAMVYYMSTTIIAAVLGVILVLAIHPGNPKLK-----KQLGPGKKNDEVSSLDAFLDLIRNLFPENLVQACFQQIQT---VTKKVLVAPPSE-EANTTKAVISMLNETMNEAPEETKIVIKKGLEFKDGMNVLGLIGFFIAFGIAMGKMGEQAKLMVEFFNILNEIVMKLVIMIMWYSPLGIACLICGKIIAIKDLEVVARQLGMYMITVIVGLIIHGGIFLPLIYFVVTRKNPFSFFAGIFQAWITALGTASSAGTLPVTFRCLEDNLGIDKRVTRFVLPVGATINMDGTALYEAVAAIFIAQMNGVILDGGQIVTVS 428 HSP 2 Score: 84.3445 bits (207), Expect = 2.312e-101 Identity = 41/80 (51.25%), Postives = 60/80 (75.00%), Query Frame = 2
Query: 1280 ATFAAIGASCVPSSGLVTVIPALASVGLPISDITLILTVDWFLDRVRTTINVLGDSLGSGIIESLLENDKIEIDWINNSD 1519
AT A+IGA+ +PS+GLVT++ L +VGLP DI+L++ VDW LDR+RT++NV+GDS G+GI+ L K E+D I++
Sbjct: 431 ATLASIGAASIPSAGLVTMLLILTAVGLPTEDISLLVAVDWLLDRMRTSVNVVGDSFGAGIVYHL---SKSELDTIDSQH 507
BLAST of slc1a-4 vs. Ensembl Mouse
Match: Slc1a3 (solute carrier family 1 (glial high affinity glutamate transporter), member 3 [Source:MGI Symbol;Acc:MGI:99917]) HSP 1 Score: 273.478 bits (698), Expect = 2.375e-94 Identity = 182/416 (43.75%), Postives = 274/416 (65.87%), Query Frame = 1
Query: 118 KRSNTMRKIHLKKFLSNNENILFVLTVFSVFTGLLAGFFIKSTFIVNEYQIYLISFPGEXXXXXXXXXXXXXXXXXXXXXXXXXETKSSGKIGLYTVLYYGITTSISLIMGMVLVVTIHPGNPKIKNLQPLENTGPTSNIGALESIFDLIRNIFPPNLIEGCFRQVATNYAIEKEN--------------IYKNFTEFPRNISKLTITMV------ESTNILGLVFFSITFGLILGQLGNKGKKMFQFFEVLNQVIMTMVTYIMWYFPXXXXXXXXXXXXXXXNLESAASSLGLYIMTVLLGLFIHGGIVLPLMYFIVCKKNPYWFFRALPQAWLASFGTASSTATLPITFKCLESNKLVSKKVTRFVLPIGATINMDGTALYEAVASIFIAQINGMVLSFGQIFSMSYICSNWSL 1305
K+ ++ K +K +L N +L LTV +V G + GF ++ + ++ ++ SFPGE+LM ML+ML+LPL+ SSL+TG++ L++K+SGK+G+ V+YY TT I++++G+++V+ IHPG +N+ G + A ++ DLIRN+FPPNL+E CF+Q T+Y EK + + N +E ++++ MV N LGLV FS+ FG ++G + +G+ + +FF+ LN+ IM +V IMWY P+GI FLI GKI+E++++ L +Y +TV++GL IH IVLPL+YF+V +KNP+ F L QA + + GT+SS+ATLPITFKCLE N V K++TRFVLP+GATINMDGTALYEA+A+IFIAQ+N L+FGQI ++S + S+
Sbjct: 31 KKVQSLTKEDVKSYLFRNAFVL--LTVTAVIVGTILGFALRP-YKMSYREVKYFSFPGELLMRMLQMLVLPLIISSLVTGMAALDSKASGKMGMRAVVYYMTTTIIAVVIGIIIVIIIHPGKGTKENMY---REGKIVQVTAADAFLDLIRNMFPPNLVEACFKQFKTSY--EKRSFKVPIQSNETLLGAVINNVSEAMETLTRIREEMVPVPGSVNGVNALGLVVFSMCFGFVIGNMKEQGQALREFFDSLNEAIMRLVAVIMWYAPLGILFLIAGKIVEMEDMGVIGGQLAMYTVTVIVGLLIHAVIVLPLLYFLVTRKNPWVFIGGLLQALITALGTSSSSATLPITFKCLEENNGVDKRITRFVLPVGATINMDGTALYEALAAIFIAQVNNFDLNFGQIITISITATAASI 438 HSP 2 Score: 92.8189 bits (229), Expect = 2.375e-94 Identity = 47/77 (61.04%), Postives = 60/77 (77.92%), Query Frame = 2
Query: 1280 ATFAAIGASCVPSSGLVTVIPALASVGLPISDITLILTVDWFLDRVRTTINVLGDSLGSGIIESL----LENDKIEI 1498
AT A+IGA+ +P +GLVT++ L SVGLP DITLI+ VDWFLDR+RTT NVLGDSLG+GI+E L L+N +E+
Sbjct: 433 ATAASIGAAGIPQAGLVTMVIVLTSVGLPTDDITLIIAVDWFLDRLRTTTNVLGDSLGAGIVEHLSRHELKNRDVEM 509
BLAST of slc1a-4 vs. UniProt/SwissProt
Match: sp|P43006|EAA2_MOUSE (Excitatory amino acid transporter 2 OS=Mus musculus OX=10090 GN=Slc1a2 PE=1 SV=1) HSP 1 Score: 305.834 bits (782), Expect = 1.401e-100 Identity = 188/395 (47.59%), Postives = 269/395 (68.10%), Query Frame = 1
Query: 172 ENILFVLTVFSVFTGLLAGFFIKSTFIVNEYQIYLISFPGEXXXXXXXXXXXXXXXXXXXXXXXXXETKSSGKIGLYTVLYYGITTSISLIMGMVLVVTIHPGNPKIKNLQPLENTGP---TSNIGALESIFDLIRNIFPPNLIEGCFRQVATNYAIEKENIYKNFTEFPRNISKLTITMVEST----------------------NILGLVFFSITFGLILGQLGNKGKKMFQFFEVLNQVIMTMVTYIMWYFPXXXXXXXXXXXXXXXNLESAASSLGLYIMTVLLGLFIHGGIVLPLMYFIVCKKNPYWFFRALPQAWLASFGTASSTATLPITFKCLESNKLVSKKVTRFVLPIGATINMDGTALYEAVASIFIAQINGMVLSFGQIFSMS 1281
+N+L LTVF V G + G ++ ++ + LI+FPG++LM MLKMLILPL+ SSLITGLS L+ K+SG++G ++YY TT I+ ++G++LV+ IHPGNPK+K + GP + +L++ DLIRN+FP NL++ CF+Q+ T + K+ + +E N +K I+M+ T N+LGL+ F I FG+ +G++G + K M +FF +LN+++M +V IMWY P+GI LI GKI+ IK+LE A LG+Y++TV++GL IHGGI LPL+YF+V +KNP+ FF + QAW+ + GTASS TLP+TF+CLE N + K+VTRFVLP+GATINMDGTALYEAVA+IFIAQ+NG++L GQI ++S
Sbjct: 43 KNLLLSLTVFGVILGAVCGGLLRLASPIHPDVVMLIAFPGDILMRMLKMLILPLIISSLITGLSGLDAKASGRLGTRAMVYYMSTTIIAAVLGVILVLAIHPGNPKLK-----KQLGPGKKNDEVSSLDAFLDLIRNLFPENLVQACFQQIQT---VTKKVLVAPPSE-EANTTKAVISMLNETMNEAPEETKIVIKKGLEFKDGMNVLGLIGFFIAFGIAMGKMGEQAKLMVEFFNILNEIVMKLVIMIMWYSPLGIACLICGKIIAIKDLEVVARQLGMYMITVIVGLIIHGGIFLPLIYFVVTRKNPFSFFAGIFQAWITALGTASSAGTLPVTFRCLEDNLGIDKRVTRFVLPVGATINMDGTALYEAVAAIFIAQMNGVILDGGQIVTVS 428 HSP 2 Score: 84.3445 bits (207), Expect = 1.401e-100 Identity = 41/80 (51.25%), Postives = 60/80 (75.00%), Query Frame = 2
Query: 1280 ATFAAIGASCVPSSGLVTVIPALASVGLPISDITLILTVDWFLDRVRTTINVLGDSLGSGIIESLLENDKIEIDWINNSD 1519
AT A+IGA+ +PS+GLVT++ L +VGLP DI+L++ VDW LDR+RT++NV+GDS G+GI+ L K E+D I++
Sbjct: 431 ATLASIGAASIPSAGLVTMLLILTAVGLPTEDISLLVAVDWLLDRMRTSVNVVGDSFGAGIVYHL---SKSELDTIDSQH 507
BLAST of slc1a-4 vs. UniProt/SwissProt
Match: sp|P31596|EAA2_RAT (Excitatory amino acid transporter 2 OS=Rattus norvegicus OX=10116 GN=Slc1a2 PE=1 SV=2) HSP 1 Score: 305.449 bits (781), Expect = 1.696e-100 Identity = 187/391 (47.83%), Postives = 265/391 (67.77%), Query Frame = 1
Query: 172 ENILFVLTVFSVFTGLLAGFFIKSTFIVNEYQIYLISFPGEXXXXXXXXXXXXXXXXXXXXXXXXXETKSSGKIGLYTVLYYGITTSISLIMGMVLVVTIHPGNPKIKNLQPLENTGP---TSNIGALESIFDLIRNIFPPNLIEGCFRQVAT-------NYAIEKENIYK--------NFTEFPRN---ISKLTITMVESTNILGLVFFSITFGLILGQLGNKGKKMFQFFEVLNQVIMTMVTYIMWYFPXXXXXXXXXXXXXXXNLESAASSLGLYIMTVLLGLFIHGGIVLPLMYFIVCKKNPYWFFRALPQAWLASFGTASSTATLPITFKCLESNKLVSKKVTRFVLPIGATINMDGTALYEAVASIFIAQINGMVLSFGQIFSMS 1281
+N+L LTVF V G + G ++ ++ + LI+FPG++LM MLKMLILPL+ SSLITGLS L+ K+SG++G ++YY TT I+ ++G++LV+ IHPGNPK+K + GP + +L++ DLIRN+FP NL++ CF+Q+ T E+ N K E P + K + + N+LGL+ F I FG+ +G++G + K M +FF +LN+++M +V IMWY P+GI LI GKI+ IK+LE A LG+Y++TV++GL IHGGI LPL+YF+V +KNP+ FF + QAW+ + GTASS TLP+TF+CLE N + K+VTRFVLP+GATINMDGTALYEAVA+IFIAQ+NG++L GQI ++S
Sbjct: 43 KNLLLSLTVFGVILGAVCGGLLRLAAPIHPDVVMLIAFPGDILMRMLKMLILPLIISSLITGLSGLDAKASGRLGTRAMVYYMSTTIIAAVLGVILVLAIHPGNPKLK-----KQLGPGKKNDEVSSLDAFLDLIRNLFPENLVQACFQQIQTVTKKVLVAPPSEEANTTKAVISLLNETMNEAPEETKIVIKKGLEFKDGMNVLGLIGFFIAFGIAMGKMGEQAKLMVEFFNILNEIVMKLVIMIMWYSPLGIACLICGKIIAIKDLEVVARQLGMYMITVIVGLIIHGGIFLPLIYFVVTRKNPFSFFAGIFQAWITALGTASSAGTLPVTFRCLEDNLGIDKRVTRFVLPVGATINMDGTALYEAVAAIFIAQMNGVILDGGQIVTVS 428 HSP 2 Score: 84.3445 bits (207), Expect = 1.696e-100 Identity = 41/80 (51.25%), Postives = 60/80 (75.00%), Query Frame = 2
Query: 1280 ATFAAIGASCVPSSGLVTVIPALASVGLPISDITLILTVDWFLDRVRTTINVLGDSLGSGIIESLLENDKIEIDWINNSD 1519
AT A+IGA+ +PS+GLVT++ L +VGLP DI+L++ VDW LDR+RT++NV+GDS G+GI+ L K E+D I++
Sbjct: 431 ATLASIGAASIPSAGLVTMLLILTAVGLPTEDISLLVAVDWLLDRMRTSVNVVGDSFGAGIVYHL---SKSELDTIDSQH 507
BLAST of slc1a-4 vs. UniProt/SwissProt
Match: sp|Q10901|EAA1_CAEEL (Excitatory amino acid transporter OS=Caenorhabditis elegans OX=6239 GN=glt-1 PE=1 SV=2) HSP 1 Score: 296.204 bits (757), Expect = 1.738e-98 Identity = 186/379 (49.08%), Postives = 255/379 (67.28%), Query Frame = 1
Query: 169 NENILFVLTVFSVFTGLLAGFFIKSTFIVNEYQIYLISFPGEXXXXXXXXXXXXXXXXXXXXXXXXXETKSSGKIGLYTVLYYGITTSISLIMGMVLVVTIHPGNPKIKNLQPLENTGPTSNIGALESIFDLIRNIFPPNLIEGCFRQVATNYAIEKENIYKN--------FTEFPRNISKLTITMVESTNILGLVFFSITFGLILGQLGNKGKKMFQFFEVLNQVIMTMVTYIMWYFPXXXXXXXXXXXXXXXNLESAASSLGLYIMTVLLGLFIHGGIVLPLMYFIVCKKNPYWFFRALPQAWLASFGTASSTATLPITFKCLESNKLVSKKVTRFVLPIGATINMDGTALYEAVASIFIAQINGMVLSFGQIFSMS 1281
+N+L VLTV SV G L GF ++ ++ I ISFPGE+LM+MLKM+ILPL+ SSLI+GL+ L+ + SGK+G V YY TT+++++ G+ LV+ IHPG+P IK G T + ++++ DL+RN+FP N+++ F+QV T Y + + KN + K ++ N+LG++ F I G+ L QLG + M QFF ++++VIM +V +MWY P GIF LI+GKILEI +L A L +Y++TVL GL IH I LPL++F+ KKNPY F R L QAW+ + GTASS+ATLPITF CLE N V ++VTRFVLP+GATINMDGTALYEAVA+IFIAQING+ LSFGQ+ ++S
Sbjct: 17 RKNLLLVLTVSSVVLGALCGFLLRG-LQLSPQNIMYISFPGELLMHMLKMMILPLIMSSLISGLAQLDARQSGKLGSLAVTYYMFTTAVAVVTGIFLVLVIHPGDPTIKKEIGTGTEGKT--VSTVDTLLDLLRNMFPENVVQATFQQVQTKYIKVRPKVVKNNDSATLAALNNGSLDYVKASVEYTSGMNVLGVIVFCIAIGISLSQLGQEAHVMVQFFVIMDKVIMKLVMTVMWYSPFGIFCLIMGKILEIHDLADTARMLAMYMVTVLSGLAIHSLISLPLIFFVTTKKNPYVFMRGLFQAWITALGTASSSATLPITFNCLEENLGVDRRVTRFVLPVGATINMDGTALYEAVAAIFIAQINGVHLSFGQVVTVS 392 HSP 2 Score: 87.0409 bits (214), Expect = 1.738e-98 Identity = 39/69 (56.52%), Postives = 56/69 (81.16%), Query Frame = 2
Query: 1280 ATFAAIGASCVPSSGLVTVIPALASVGLPISDITLILTVDWFLDRVRTTINVLGDSLGSGIIESLLEND 1486
AT A+IGA+ VPS+GLVT++ L +VGLP+ D++LI+ VDW LDR+RT+INVLGD++G+GI+ + D
Sbjct: 395 ATLASIGAASVPSAGLVTMLLVLTAVGLPVKDVSLIVAVDWLLDRIRTSINVLGDAMGAGIVYHYSKAD 463
BLAST of slc1a-4 vs. UniProt/SwissProt
Match: sp|Q25605|EAAT_ONCVO (Excitatory amino acid transporter OS=Onchocerca volvulus OX=6282 GN=GLT-1 PE=2 SV=1) HSP 1 Score: 291.967 bits (746), Expect = 2.743e-97 Identity = 183/379 (48.28%), Postives = 252/379 (66.49%), Query Frame = 1
Query: 169 NENILFVLTVFSVFTGLLAGFFIKSTFIVNEYQIYLISFPGEXXXXXXXXXXXXXXXXXXXXXXXXXETKSSGKIGLYTVLYYGITTSISLIMGMVLVVTIHPGNPKIKNLQPLENTGPTSNIGALESIFDLIRNIFPPNLIEGCFRQVATNYAIEKENIYKN--------FTEFPRNISKLTITMVESTNILGLVFFSITFGLILGQLGNKGKKMFQFFEVLNQVIMTMVTYIMWYFPXXXXXXXXXXXXXXXNLESAASSLGLYIMTVLLGLFIHGGIVLPLMYFIVCKKNPYWFFRALPQAWLASFGTASSTATLPITFKCLESNKLVSKKVTRFVLPIGATINMDGTALYEAVASIFIAQINGMVLSFGQIFSMS 1281
+N+L VLTV SV G L GF ++ ++ I ISFPGE+LM+MLKM+ILPL+ SSLI+GL+ L+ + SGK+G V YY TT+++++ G+ LV+ IHPG+P IK G T + ++++ DL+RN+FP N+++ F+QV T Y + + KN + K ++ N+LG++ F I G+ L QLG + M QFF ++++VIM +V +MWY P GI LI+GKILEI +L A L +Y++TVL GL IH I LPL++F+ KKNPY F R L QAW+ GTASS+ TLPIT+ CLE N V ++VTRFVLP+GATINMDGTALYEAVA+IFIAQING+ LSFGQ+ ++S
Sbjct: 6 RKNLLLVLTVSSVVLGALCGFLLRG-LQLSPQNIMYISFPGELLMHMLKMMILPLIMSSLISGLAQLDARQSGKLGSLAVTYYMFTTAVAVVTGIFLVLVIHPGDPTIKKEIGTGTEGKT--VSTVDTLLDLLRNMFPENVVQATFQQVQTKYIKVRPKVVKNNDSATLAALNNGSLDYVKASVEYTSGMNVLGVIVFCIAIGISLSQLGQEAHVMVQFFVIMDKVIMKLVMTVMWYSPFGILCLIMGKILEIHDLADTARMLAMYMVTVLSGLAIHSLISLPLIFFVTTKKNPYVFMRGLFQAWITGLGTASSSDTLPITYICLEENLGVDRRVTRFVLPVGATINMDGTALYEAVAAIFIAQINGVHLSFGQVVTVS 381 HSP 2 Score: 87.0409 bits (214), Expect = 2.743e-97 Identity = 39/69 (56.52%), Postives = 56/69 (81.16%), Query Frame = 2
Query: 1280 ATFAAIGASCVPSSGLVTVIPALASVGLPISDITLILTVDWFLDRVRTTINVLGDSLGSGIIESLLEND 1486
AT A+IGA+ VPS+GLVT++ L +VGLP+ D++LI+ VDW LDR+RT+INVLGD++G+GI+ + D
Sbjct: 384 ATLASIGAASVPSAGLVTMLLVLTAVGLPVKDVSLIVAVDWLLDRIRTSINVLGDAMGAGIVYHYSKAD 452
BLAST of slc1a-4 vs. UniProt/SwissProt
Match: sp|O57321|EAA1_AMBTI (Excitatory amino acid transporter 1 OS=Ambystoma tigrinum OX=8305 GN=SLC1A3 PE=1 SV=1) HSP 1 Score: 281.567 bits (719), Expect = 8.912e-96 Identity = 188/417 (45.08%), Postives = 272/417 (65.23%), Query Frame = 1
Query: 118 KRSNTMRKIHLKKFLSNNENILFVLTVFSVFTGLLAGFFIKSTFIVNEYQIYLISFPGEXXXXXXXXXXXXXXXXXXXXXXXXXETKSSGKIGLYTVLYYGITTSISLIMGMVLVVTIHPGNPKIKNLQPLENTGPTSNIGALESIFDLIRNIFPPNLIEGCFRQVATNYAIEKE---------------NIYKNFTEFPRNISKLTITM------VESTNILGLVFFSITFGLILGQLGNKGKKMFQFFEVLNQVIMTMVTYIMWYFPXXXXXXXXXXXXXXXNLESAASSLGLYIMTVLLGLFIHGGIVLPLMYFIVCKKNPYWFFRALPQAWLASFGTASSTATLPITFKCLESNKLVSKKVTRFVLPIGATINMDGTALYEAVASIFIAQINGMVLSFGQIFSMSYICSNWSL 1305
K+ + K +K FL N +LF TV +V G + GF ++S + + ++ SFPGE+LM ML+ML+LPL+ SSL+TG++ L++K+SGK+GL V+YY TT I++ +G+V+V+ +HPG +++ G + A ++ DLIRN+FPPN++E CF+Q T+Y EK+ ++ N +E ++K+ M V N LGLV FS+ FGL++G + +GK + FF+ LN+ IM +V IMWY PIGI FLI GKI E++++ LG+Y +TV++GL IH IVLPL+YF V +KNP+ F + QA + + GT+SS+ATLPITFKCLE N V K+VTRFVLP+GATINMDGTALYEA+A+IFIAQ+N L+FGQI ++S + S+
Sbjct: 31 KKVQNITKDDVKGFLKRNGFVLF--TVIAVVVGSILGFSVRS-YHMTFRELKYFSFPGELLMRMLQMLVLPLIVSSLVTGMAALDSKASGKMGLRAVVYYMTTTVIAVFIGIVIVIIVHPGKGTKEHMH---REGKIEPVTAADAFLDLIRNMFPPNMVEACFKQFKTSY--EKKIFKVTMPANETAVMTSVLNNVSEAMETLTKMREEMIPVPGAVNGVNALGLVVFSMCFGLVIGNMKEQGKALKDFFDSLNEAIMRLVAVIMWYAPIGILFLIAGKIAEMEDMGVVGGQLGMYTVTVIIGLLIHAVIVLPLLYFAVTRKNPWVFIGGILQALITALGTSSSSATLPITFKCLEENNKVDKRVTRFVLPVGATINMDGTALYEALAAIFIAQVNNYDLNFGQILTISITATAASI 439 HSP 2 Score: 92.4337 bits (228), Expect = 8.912e-96 Identity = 44/69 (63.77%), Postives = 56/69 (81.16%), Query Frame = 2
Query: 1280 ATFAAIGASCVPSSGLVTVIPALASVGLPISDITLILTVDWFLDRVRTTINVLGDSLGSGIIESLLEND 1486
AT A+IGA+ +P +GLVT++ L SVGLP DITLI+ VDWFLDR+RTT NVLGDSLG+GI+E L ++
Sbjct: 434 ATAASIGAAGIPQAGLVTMVIVLTSVGLPTDDITLIIAVDWFLDRLRTTTNVLGDSLGAGIVEHLSRHE 502
BLAST of slc1a-4 vs. TrEMBL
Match: A0A0H3YIT8 (Slc1a-4 (Fragment) OS=Schmidtea mediterranea OX=79327 GN=slc1a-4 PE=2 SV=1) HSP 1 Score: 673.315 bits (1736), Expect = 0.000e+0 Identity = 382/383 (99.74%), Postives = 383/383 (100.00%), Query Frame = 1
Query: 133 MRKIHLKKFLSNNENILFVLTVFSVFTGLLAGFFIKSTFIVNEYQIYLISFPGEXXXXXXXXXXXXXXXXXXXXXXXXXETKSSGKIGLYTVLYYGITTSISLIMGMVLVVTIHPGNPKIKNLQPLENTGPTSNIGALESIFDLIRNIFPPNLIEGCFRQVATNYAIEKENIYKNFTEFPRNISKLTITMVESTNILGLVFFSITFGLILGQLGNKGKKMFQFFEVLNQVIMTMVTYIMWYFPXXXXXXXXXXXXXXXNLESAASSLGLYIMTVLLGLFIHGGIVLPLMYFIVCKKNPYWFFRALPQAWLASFGTASSTATLPITFKCLESNKLVSKKVTRFVLPIGATINMDGTALYEAVASIFIAQINGMVLSFGQIFSMS 1281
MRKIHLKKFLSNNENILFVLTVFSVFTGLLAGFFIKSTFIVNEYQIYLISFPGEMLMNMLKMLILPLLTSSLITGLSVLETKSSGKIGLYTVLYYGITTSISLIMGMVLVVTIHPGNPKIKNLQPLENTGPTSNIGALESIFDLIRNIFPPNLIEGCFRQVATNYAIEKENIYKNFTEFPRNISKLTITMVESTNILGLVFFSITFGLILGQLGNKGKKMFQFFEVLNQVIMTMVTYIMWYFPIGIFFLIIGKILEIKNLESAASSLGLYIMTVLLGLFIHGGIVLPLMYFIVCKKNPYWFFRALPQAWLASFGTASSTATLPITFKCLESNKLVSKKVTRFVLPIGATINMDGTALYEAVASIFIAQINGMVLS+GQIFSMS
Sbjct: 1 MRKIHLKKFLSNNENILFVLTVFSVFTGLLAGFFIKSTFIVNEYQIYLISFPGEMLMNMLKMLILPLLTSSLITGLSVLETKSSGKIGLYTVLYYGITTSISLIMGMVLVVTIHPGNPKIKNLQPLENTGPTSNIGALESIFDLIRNIFPPNLIEGCFRQVATNYAIEKENIYKNFTEFPRNISKLTITMVESTNILGLVFFSITFGLILGQLGNKGKKMFQFFEVLNQVIMTMVTYIMWYFPIGIFFLIIGKILEIKNLESAASSLGLYIMTVLLGLFIHGGIVLPLMYFIVCKKNPYWFFRALPQAWLASFGTASSTATLPITFKCLESNKLVSKKVTRFVLPIGATINMDGTALYEAVASIFIAQINGMVLSYGQIFSMS 383 HSP 2 Score: 163.696 bits (413), Expect = 5.431e-41 Identity = 83/84 (98.81%), Postives = 83/84 (98.81%), Query Frame = 2
Query: 1280 ATFAAIGASCVPSSGLVTVIPALASVGLPISDITLILTVDWFLDRVRTTINVLGDSLGSGIIESLLENDKIEIDWINNSDLDGK 1531
ATFAAIGASCVPSSGLVTVIPALASVGLPISDITLILTVDWFLDRVRTTINVLGDSLGSGIIESLLENDKIEID INNSDLDGK
Sbjct: 386 ATFAAIGASCVPSSGLVTVIPALASVGLPISDITLILTVDWFLDRVRTTINVLGDSLGSGIIESLLENDKIEIDRINNSDLDGK 469
BLAST of slc1a-4 vs. TrEMBL
Match: A0A0H3YEU5 (Amino acid transporter OS=Schmidtea mediterranea OX=79327 GN=slc1a-5 PE=2 SV=1) HSP 1 Score: 381.333 bits (978), Expect = 1.613e-124 Identity = 232/380 (61.05%), Postives = 293/380 (77.11%), Query Frame = 1
Query: 145 HLKKFLSNNENILFVLTVFSVFTGLLAGFFIKSTFIVNEYQIYLISFPGEXXXXXXXXXXXXXXXXXXXXXXXXXETKSSGKIGLYTVLYYGITTSISLIMGMVLVVTIHPGNPKIK-NLQPLENTGPTSNIGALESIFDLIRNIFPPNLIEGCFRQVATNYAIEKENIYKNFTEFPRNISKLTITMVESTNILGLVFFSITFGLILGQLGNKGKKMFQFFEVLNQVIMTMVTYIMWYFPXXXXXXXXXXXXXXXNLESAASSLGLYIMTVLLGLFIHGGIVLPLMYFIVCKKNPYWFFRALPQAWLASFGTASSTATLPITFKCLESNKLVSKKVTRFVLPIGATINMDGTALYEAVASIFIAQINGMVLSFGQIFSMS 1281
L KF N +N+L LT+ SV GL G +K +++ Q+YLI FPGEMLMNMLKMLI+PL+ SSLITGLS L+ KSSGK+GLY ++YY +TT +++I+G++LVV IHPGNP IK +L P T T + L++ DLIRN+ P NLIE CFRQ TNY + E+ Y+N T+ N++K+ I ESTN+LGLV FSI FGLILGQ+G + + MF+FF VLN+V+M +V IMWY PIGIFFLI+GKILEIK+L + ASSLG+Y++TVLLGL IHG I L L++F+ +KNP+ +F + QAW+ + GTASS+ATLPITFKCLE N V K+VTRFVLPIGATINMDGTALYEAVASIFIAQING+ LSFGQIF++S
Sbjct: 10 KLLKFFKNKDNVLVALTIASVVLGLAMGLLLKFVATISDRQVYLIGFPGEMLMNMLKMLIIPLIVSSLITGLSGLDAKSSGKMGLYAIVYYVVTTLMAVILGIILVVAIHPGNPNIKKSLGPGSMTKKT-DTDTLDAFLDLIRNLLPVNLIEACFRQSQTNYVTKLEHFYENGTKVFINVTKIVINHQESTNVLGLVSFSIAFGLILGQMGKEARIMFEFFGVLNEVVMKLVKLIMWYSPIGIFFLIVGKILEIKDLANTASSLGMYMVTVLLGLTIHGCITLNLIFFVFTRKNPFVYFHGMLQAWVTALGTASSSATLPITFKCLEENNGVDKRVTRFVLPIGATINMDGTALYEAVASIFIAQINGIYLSFGQIFTIS 388 HSP 2 Score: 96.2857 bits (238), Expect = 1.613e-124 Identity = 48/73 (65.75%), Postives = 59/73 (80.82%), Query Frame = 2
Query: 1280 ATFAAIGASCVPSSGLVTVIPALASVGLPISDITLILTVDWFLDRVRTTINVLGDSLGSGIIESLLENDKIEI 1498
AT AAIGA+ VPS+GLVT+I L SVGLPI+DITLIL VDW LDRVRT+INVLGD+ G+GI++ L + E+
Sbjct: 391 ATLAAIGAASVPSAGLVTMILVLTSVGLPINDITLILAVDWLLDRVRTSINVLGDAFGAGIVDHLCKKQLEEL 463
BLAST of slc1a-4 vs. TrEMBL
Match: A0A3P6T680 (Amino acid transporter OS=Litomosoides sigmodontis OX=42156 GN=NLS_LOCUS4039 PE=3 SV=1) HSP 1 Score: 318.546 bits (815), Expect = 6.536e-103 Identity = 192/379 (50.66%), Postives = 267/379 (70.45%), Query Frame = 1
Query: 169 NENILFVLTVFSVFTGLLAGFFIKSTFIVNEYQIYLISFPGEXXXXXXXXXXXXXXXXXXXXXXXXXETKSSGKIGLYTVLYYGITTSISLIMGMVLVVTIHPGNPKIKNLQPLENTGPTSNIGALESIFDLIRNIFPPNLIEGCFRQVATNY-AIEKENIYKNFTEFPRNISKLTITMVEST-------NILGLVFFSITFGLILGQLGNKGKKMFQFFEVLNQVIMTMVTYIMWYFPXXXXXXXXXXXXXXXNLESAASSLGLYIMTVLLGLFIHGGIVLPLMYFIVCKKNPYWFFRALPQAWLASFGTASSTATLPITFKCLESNKLVSKKVTRFVLPIGATINMDGTALYEAVASIFIAQINGMVLSFGQIFSMS 1281
N+L VLTV SV G+L GF I F + I L+SFPGE+LM MLK++ILPL+ SSLI+GL+ L+ K SG++G + YY TT I++I G++LV+TIHPG+P IK+ + + LE+ DL+RN FP N+I+ F+QV T Y I+ + I +N +E + ++ ++TM++ T N+LG++ F I+FG++L QLG + M FF +++QVIM +V IMWY P+GI LI GKILEI +L + A L +Y++TVLLGL +H I LP+++FI +KNP+ + R L QAW+ + GTASS+ATLPITFKCLE N + ++VTRFVLP+GATINMDGTALYEAVA+IFIAQ NG+VLSFGQ+ ++S
Sbjct: 6 RRNLLLVLTVTSVLMGILLGF-IGRLFNLTLQSIVLVSFPGEILMRMLKLMILPLIISSLISGLAQLDAKQSGRLGFIAIFYYVSTTVIAVITGILLVLTIHPGDPAIKH--DIGEDTEAKTVSTLETFLDLLRNTFPENIIQATFQQVQTKYIPIKPKIIKRNSSEILQAVANGSLTMMKPTIEYTAGMNVLGIIVFCISFGVVLSQLGEQAHTMVNFFYIMDQVIMRLVMLIMWYSPVGIMCLIAGKILEIDDLANMARMLAMYVVTVLLGLIVHALISLPMLFFICTRKNPFAYMRGLLQAWVTALGTASSSATLPITFKCLEENLGIDRRVTRFVLPVGATINMDGTALYEAVAAIFIAQTNGVVLSFGQVITIS 381 HSP 2 Score: 87.0409 bits (214), Expect = 6.536e-103 Identity = 40/74 (54.05%), Postives = 55/74 (74.32%), Query Frame = 2
Query: 1280 ATFAAIGASCVPSSGLVTVIPALASVGLPISDITLILTVDWFLDRVRTTINVLGDSLGSGIIESLLENDKIEID 1501
AT A+IGA+ VPS+GLVT++ L +VGLP+ D++LI+ VDW LDR+RT+INVLGD+ G+GI+ ID
Sbjct: 384 ATLASIGAASVPSAGLVTMLIVLTAVGLPVKDVSLIVAVDWLLDRIRTSINVLGDAFGAGIVHHFSRKQLAVID 457
BLAST of slc1a-4 vs. TrEMBL
Match: A0A0H3YF08 (Amino acid transporter OS=Schmidtea mediterranea OX=79327 GN=slc1a-2 PE=2 SV=1) HSP 1 Score: 314.309 bits (804), Expect = 1.475e-102 Identity = 197/394 (50.00%), Postives = 270/394 (68.53%), Query Frame = 1
Query: 145 HLKKFLSNNENILFVLTVFSVFTGLLAGFFIKSTFIVNEYQIYLISFPGEXXXXXXXXXXXXXXXXXXXXXXXXXETKSSGKIGLYTVLYYGITTSISLIMGMVLVVTIHPGNPKIKNLQPLENTGPTSNIGALESIFDLIRNIFPPNLIEGCFRQVATNYAIEK----ENIYKNFTEFPRNISKLTIT-----------MVESTNILGLVFFSITFGLILGQLGNKGKKMFQFFEVLNQVIMTMVTYIMWYFPXXXXXXXXXXXXXXXNLESAASSLGLYIMTVLLGLFIHGGIVLPLMYFIVCKKNPYWFFRALPQAWLASFGTASSTATLPITFKCLESNKLVSKKVTRFVLPIGATINMDGTALYEAVASIFIAQINGMVLSFGQIFSMS 1281
+K N +NIL LTV SV G+ G +K T ++Y + LISFPGE+LMNMLKMLI+PL+ SSLI+GL+ L+ KSSG+IG + ++YY TT +++++G++LVV IHPGN IK Q + T L+S DL+RNIFPPN+I+ +Q+++ Y + + + K+ + LT + +STN+LG+V FS+ FGL+L Q+G K M QFF +LN+V+M MV IMWY PIGIF L+IGK+L+I++LE A++LG+Y++TV+ GLFIH L L+Y ++C+K+P FF+ + QAW+ + GTASS ATLPITF+CLE + K+VTRFVLPIGATINMDGTALYEAVASIFIAQIN L QIF++S
Sbjct: 45 KVKGAFKNADNILVSLTVLSVVLGMGVGLVVKLTLRYDDYAVMLISFPGELLMNMLKMLIIPLIVSSLISGLAGLDPKSSGQIGKWALIYYFSTTMMAVVLGIILVVLIHPGNADIKK-QLGQGTNKRRAPSTLDSFLDLLRNIFPPNIIQAAMQQISSKYVNKTKAVTDRMLKDMLSQNKTTEGLTTNSTITYEVTATELTDSTNVLGIVAFSMWFGLVLSQMGEKALIMVQFFALLNEVVMKMVKVIMWYSPIGIFSLVIGKVLQIESLEETAAALGMYMLTVITGLFIHACFTLTLIYVVICRKSPIGFFKGIFQAWITALGTASSAATLPITFRCLEEKIGIDKRVTRFVLPIGATINMDGTALYEAVASIFIAQINARKLEPIQIFTVS 437 HSP 2 Score: 90.1225 bits (222), Expect = 1.475e-102 Identity = 45/74 (60.81%), Postives = 56/74 (75.68%), Query Frame = 2
Query: 1280 ATFAAIGASCVPSSGLVTVIPALASVGLPISDITLILTVDWFLDRVRTTINVLGDSLGSGIIESLLENDKIEID 1501
AT AAIGA+ VPS+GLVT+I L SVGLP DI+LILTVDW LDR+RT+INVLGD+ G+ ++ L + E D
Sbjct: 440 ATLAAIGAASVPSAGLVTMIMVLTSVGLPTDDISLILTVDWLLDRLRTSINVLGDAYGAAVVHHLCKKTLDEQD 513
BLAST of slc1a-4 vs. TrEMBL
Match: A0A3Q2ZLX5 (Amino acid transporter OS=Hippocampus comes OX=109280 PE=3 SV=1) HSP 1 Score: 322.013 bits (824), Expect = 2.684e-102 Identity = 187/371 (50.40%), Postives = 267/371 (71.97%), Query Frame = 1
Query: 172 ENILFVLTVFSVFTGLLAGFFIKSTFIVNEYQIYLISFPGEXXXXXXXXXXXXXXXXXXXXXXXXXETKSSGKIGLYTVLYYGITTSISLIMGMVLVVTIHPGNPKIKNLQPLENTGPTSNIGALESIFDLIRNIFPPNLIEGCFRQVATNYAIEKENIYKNFTEFPRNIS-KLTITMVESTNILGLVFFSITFGLILGQLGNKGKKMFQFFEVLNQVIMTMVTYIMWYFPXXXXXXXXXXXXXXXNLESAASSLGLYIMTVLLGLFIHGGIVLPLMYFIVCKKNPYWFFRALPQAWLASFGTASSTATLPITFKCLESNKLVSKKVTRFVLPIGATINMDGTALYEAVASIFIAQINGMVLSFGQIFSMS 1281
+N++ LT+ VF G +AG ++ + I +ISFPGE+LM MLKMLILPL+ SSL+TGL+ L+ KSSG++G ++YY TT I+ ++G++LV+ IHPGNPK++ L ++ ++++ FDLIRN+FP NL++ CF+Q+ T K + N T+ P + K ++ N+LGL+ F + FG+I+G++G K K M +FF VLN++IM +V+ IMWY PIGI LI GKI+ I +LE A LG+Y++TV++GL IHGGI LPL+YF++ K+NP+ FF + QAW+ + GTASS TLP+TF+CLE N + K+VTRFVLP+GATINMDGTALYEAVA+IFIAQ+NG+VL +GQI ++S
Sbjct: 34 KNMVLTLTILGVFLGSIAGMLLRHISPLPPDVIMIISFPGEILMRMLKMLILPLVVSSLVTGLAGLDAKSSGRLGTRAMVYYMTTTVIAAVLGVILVLLIHPGNPKLR--ANLGQGKKNDDVSSVDAFFDLIRNLFPENLVQACFQQIQT--VTTKVQVPTNRTKAPPQFTIKRSLQFKSGMNVLGLIGFFVAFGVIMGKMGEKAKLMLEFFNVLNEIIMRIVSAIMWYSPIGIACLICGKIISIADLEVVARQLGMYMITVIVGLIIHGGIFLPLIYFVIVKQNPFKFFMGMFQAWVTALGTASSAGTLPVTFRCLEENLKIDKRVTRFVLPVGATINMDGTALYEAVAAIFIAQMNGIVLDWGQIVTVS 400 HSP 2 Score: 81.6481 bits (200), Expect = 2.684e-102 Identity = 36/69 (52.17%), Postives = 55/69 (79.71%), Query Frame = 2
Query: 1280 ATFAAIGASCVPSSGLVTVIPALASVGLPISDITLILTVDWFLDRVRTTINVLGDSLGSGIIESLLEND 1486
AT A++GA+ +PS+GLVT++ L +VGLP DI+L++ VDW LDR RT++NV+GDS G+GI+ L +++
Sbjct: 403 ATLASVGAASIPSAGLVTMLLILTAVGLPTQDISLLVAVDWLLDRFRTSVNVIGDSYGAGIVYHLSKDE 471
BLAST of slc1a-4 vs. Ensembl Cavefish
Match: slc1a9 (excitatory amino acid transporter 2-like [Source:NCBI gene;Acc:103041419]) HSP 1 Score: 307.375 bits (786), Expect = 7.832e-102 Identity = 183/370 (49.46%), Postives = 261/370 (70.54%), Query Frame = 1
Query: 172 ENILFVLTVFSVFTGLLAGFFIKSTFIVNEYQIYLISFPGEXXXXXXXXXXXXXXXXXXXXXXXXXETKSSGKIGLYTVLYYGITTSISLIMGMVLVVTIHPGNPKIKNLQPLENTGPTSNIGALESIFDLIRNIFPPNLIEGCFRQVATNYAIEKENIYKNFTEFPRNISKLTITMVESTNILGLVFFSITFGLILGQLGNKGKKMFQFFEVLNQVIMTMVTYIMWYFPXXXXXXXXXXXXXXXNLESAASSLGLYIMTVLLGLFIHGGIVLPLMYFIVCKKNPYWFFRALPQAWLASFGTASSTATLPITFKCLESNKLVSKKVTRFVLPIGATINMDGTALYEAVASIFIAQINGMVLSFGQIFSMS 1281
N+L LTV V G + G ++ ++ + LI+FPG++LM MLKMLILPL+ SSLITGL+ L+ +SSG++G ++YY TT I+ ++G++LV+ IHPGNPK++ Q ++ + +L++ DLIRN+FP NL++ CF+QV T ++K + + P I+K + N+LGL+ F ITFG+ +G++G KGK M FF +LN++IM MV+ IMWY P+GI LI GKI I +LE A LG+Y++TV++GL IHGGI+LP+++F V +KNP+ F+ + QAW+ + GTASS TLP+TF+CLE N + K+VTRFVLPIGATINMDGTALYEAVA+IFIAQ+N + L GQI ++S
Sbjct: 50 RNLLLALTVLGVIGGTVLGLLLRYLPELDADILMLIAFPGDILMRMLKMLILPLIISSLITGLAGLDARSSGRMGTRAMVYYMSTTVIAAVLGVILVLGIHPGNPKLRGTQ-ARSSNKDQEVSSLDAFLDLIRNLFPENLVQACFQQVQT--VLKKVAVPVDNQTEPILINKKKLEFKWGMNVLGLIGFFITFGIFMGKMGEKGKLMTDFFNILNEIIMKMVSMIMWYSPVGIASLICGKIAAIGDLEVVARQLGMYMVTVIVGLIIHGGIILPIIFFAVTRKNPFVFYSGIFQAWITALGTASSAGTLPVTFRCLEENLKIDKRVTRFVLPIGATINMDGTALYEAVAAIFIAQMNDIDLDGGQIATVS 416 HSP 2 Score: 83.9593 bits (206), Expect = 7.832e-102 Identity = 39/74 (52.70%), Postives = 58/74 (78.38%), Query Frame = 2
Query: 1280 ATFAAIGASCVPSSGLVTVIPALASVGLPISDITLILTVDWFLDRVRTTINVLGDSLGSGIIESLLENDKIEID 1501
AT A++GA+ +PS+GLVT++ L +VGLP DI+L++ VDW LDR+RT+INV+GDS G+GI++ L + +ID
Sbjct: 419 ATLASVGAASIPSAGLVTMLLILTAVGLPTQDISLLIAVDWLLDRMRTSINVVGDSFGAGIVDFLSRAELAQID 492
BLAST of slc1a-4 vs. Ensembl Cavefish
Match: slc1a9 (excitatory amino acid transporter 2-like [Source:NCBI gene;Acc:103041419]) HSP 1 Score: 306.99 bits (785), Expect = 9.721e-102 Identity = 183/370 (49.46%), Postives = 261/370 (70.54%), Query Frame = 1
Query: 172 ENILFVLTVFSVFTGLLAGFFIKSTFIVNEYQIYLISFPGEXXXXXXXXXXXXXXXXXXXXXXXXXETKSSGKIGLYTVLYYGITTSISLIMGMVLVVTIHPGNPKIKNLQPLENTGPTSNIGALESIFDLIRNIFPPNLIEGCFRQVATNYAIEKENIYKNFTEFPRNISKLTITMVESTNILGLVFFSITFGLILGQLGNKGKKMFQFFEVLNQVIMTMVTYIMWYFPXXXXXXXXXXXXXXXNLESAASSLGLYIMTVLLGLFIHGGIVLPLMYFIVCKKNPYWFFRALPQAWLASFGTASSTATLPITFKCLESNKLVSKKVTRFVLPIGATINMDGTALYEAVASIFIAQINGMVLSFGQIFSMS 1281
N+L LTV V G + G ++ ++ + LI+FPG++LM MLKMLILPL+ SSLITGL+ L+ +SSG++G ++YY TT I+ ++G++LV+ IHPGNPK++ Q ++ + +L++ DLIRN+FP NL++ CF+QV T ++K + + P I+K + N+LGL+ F ITFG+ +G++G KGK M FF +LN++IM MV+ IMWY P+GI LI GKI I +LE A LG+Y++TV++GL IHGGI+LP+++F V +KNP+ F+ + QAW+ + GTASS TLP+TF+CLE N + K+VTRFVLPIGATINMDGTALYEAVA+IFIAQ+N + L GQI ++S
Sbjct: 45 RNLLLALTVLGVIGGTVLGLLLRYLPELDADILMLIAFPGDILMRMLKMLILPLIISSLITGLAGLDARSSGRMGTRAMVYYMSTTVIAAVLGVILVLGIHPGNPKLRGTQ-ARSSNKDQEVSSLDAFLDLIRNLFPENLVQACFQQVQT--VLKKVAVPVDNQTEPILINKKKLEFKWGMNVLGLIGFFITFGIFMGKMGEKGKLMTDFFNILNEIIMKMVSMIMWYSPVGIASLICGKIAAIGDLEVVARQLGMYMVTVIVGLIIHGGIILPIIFFAVTRKNPFVFYSGIFQAWITALGTASSAGTLPVTFRCLEENLKIDKRVTRFVLPIGATINMDGTALYEAVAAIFIAQMNDIDLDGGQIATVS 411 HSP 2 Score: 83.9593 bits (206), Expect = 9.721e-102 Identity = 39/74 (52.70%), Postives = 58/74 (78.38%), Query Frame = 2
Query: 1280 ATFAAIGASCVPSSGLVTVIPALASVGLPISDITLILTVDWFLDRVRTTINVLGDSLGSGIIESLLENDKIEID 1501
AT A++GA+ +PS+GLVT++ L +VGLP DI+L++ VDW LDR+RT+INV+GDS G+GI++ L + +ID
Sbjct: 414 ATLASVGAASIPSAGLVTMLLILTAVGLPTQDISLLIAVDWLLDRMRTSINVVGDSFGAGIVDFLSRAELAQID 487
BLAST of slc1a-4 vs. Ensembl Cavefish
Match: slc1a3b (solute carrier family 1 member 3 [Source:NCBI gene;Acc:103023054]) HSP 1 Score: 294.278 bits (752), Expect = 4.876e-100 Identity = 186/411 (45.26%), Postives = 273/411 (66.42%), Query Frame = 1
Query: 118 KRSNTMRKIHLKKFLSNNENILFVLTVFSVFTGLLAGFFIKSTFIVNEYQIYLISFPGEXXXXXXXXXXXXXXXXXXXXXXXXXETKSSGKIGLYTVLYYGITTSISLIMGMVLVVTIHPGN---PKIKNLQPLENTGPTSNIGALESIFDLIRNIFPPNLIEGCFRQVATNYA--------IEKENIYKNFTEFPRNISKLTITMVEST----NILGLVFFSITFGLILGQLGNKGKKMFQFFEVLNQVIMTMVTYIMWYFPXXXXXXXXXXXXXXXNLESAASSLGLYIMTVLLGLFIHGGIVLPLMYFIVCKKNPYWFFRALPQAWLASFGTASSTATLPITFKCLESNKLVSKKVTRFVLPIGATINMDGTALYEAVASIFIAQINGMVLSFGQIFSMSYICSNWSL 1305
K+ + K +K FL N +LF T+ +V G++ GF ++ + ++ ++ SFPGE+LM ML+ML+LPLL SSLITG++ L++++SGK+G+ V+YY TT I++ +G+++V+ IHPG + Q +E+ P ++ DLIRN+FPPNL++ C +Q T Y I E+I+ N T + IS+ I + T N LGLV FS+ FGLI+G + +G+ + +FF LN+ IM +V IMWY PIGI FLI GKI+E+ ++ LG+Y +TV++GL IHG ++LP +YF++ +KNP+ F L QA + + GT+SS+ATLPITFKCLE N V K+VTRFVLP+GATINMDGTALYEA+A+IFIAQ+N M ++FGQI ++S + S+
Sbjct: 31 KKVQDITKDDVKSFLRKNAFVLF--TIAAVVVGIMLGFALRP-YRMSYREVKYFSFPGELLMRMLQMLVLPLLVSSLITGMAALDSRASGKMGMRAVIYYMTTTFIAVFIGIIMVLIIHPGKGSKDEFTQQQKIEHVSPA------DAFLDLIRNMFPPNLVQACTQQFKTQYGKRVINVKVIVNESIF-NLTNATQEISREEIIPISGTTSGVNALGLVVFSMCFGLIIGNMKEEGEALREFFNSLNEAIMRLVAIIMWYAPIGILFLIAGKIVEMDDITEMGGQLGMYTITVIIGLLIHGMVILPTLYFVITRKNPFIFITGLLQALITALGTSSSSATLPITFKCLEENNKVDKRVTRFVLPVGATINMDGTALYEALAAIFIAQVNNMDMNFGQIITISITATAASI 431 HSP 2 Score: 91.2781 bits (225), Expect = 4.876e-100 Identity = 45/72 (62.50%), Postives = 58/72 (80.56%), Query Frame = 2
Query: 1280 ATFAAIGASCVPSSGLVTVIPALASVGLPISDITLILTVDWFLDRVRTTINVLGDSLGSGIIESLLENDKIE 1495
AT A+IGA+ +P +GLVT++ L SVGLP DITLI+ VDWFLDR+RTT NVLGDS+G+GIIE L D+++
Sbjct: 426 ATAASIGAAGIPQAGLVTMVIVLTSVGLPTDDITLIIAVDWFLDRLRTTTNVLGDSIGAGIIE-FLSKDELQ 496
BLAST of slc1a-4 vs. Ensembl Cavefish
Match: slc1a9 (excitatory amino acid transporter 2-like [Source:NCBI gene;Acc:103041419]) HSP 1 Score: 298.901 bits (764), Expect = 3.110e-99 Identity = 182/374 (48.66%), Postives = 262/374 (70.05%), Query Frame = 1
Query: 172 ENILFVLTVFSVFTGLLAGFFIKSTFIVNEYQIYLISFPGEXXXXXXXXXXXXXXXXXXXXXXXXXETKSSGKIGLYTVLYYGITTSISLIMGMVLVVTIHPGNPKIKNLQPLENTGPTSNIGALESIFDLIRNIFPPNLIEGCFRQVATNYAIEKENIYKNFTEFPRNISKLTITMVESTNIL----GLVFFSITFGLILGQLGNKGKKMFQFFEVLNQVIMTMVTYIMWYFPXXXXXXXXXXXXXXXNLESAASSLGLYIMTVLLGLFIHGGIVLPLMYFIVCKKNPYWFFRALPQAWLASFGTASSTATLPITFKCLESNKLVSKKVTRFVLPIGATINMDGTALYEAVASIFIAQINGMVLSFGQIFSMS 1281
N+L LTV V G + G ++ ++ + LI+FPG++LM MLKMLILPL+ SSLITGL+ L+ +SSG++G ++YY TT I+ ++G++LV+ IHPGNPK++ Q ++ + +L++ DLIRN+FP NL++ CF+QV + +++ +P I++ I +E +N L GL+ F ITFG+ +G++G KGK M FF +LN++IM MV+ IMWY P+GI LI GKI I +LE A LG+Y++TV++GL IHGGI+LP+++F V +KNP+ F+ + QAW+ + GTASS TLP+TF+CLE N + K+VTRFVLPIGATINMDGTALYEAVA+IFIAQ+N + L GQI ++S
Sbjct: 34 RNLLLALTVLGVIGGTVLGLLLRYLPELDADILMLIAFPGDILMRMLKMLILPLIISSLITGLAGLDARSSGRMGTRAMVYYMSTTVIAAVLGVILVLGIHPGNPKLRGTQA-RSSNKDQEVSSLDAFLDLIRNLFPENLVQACFQQV-------QLSLFAPL--YPSEINRQFI--LELSNCLCLCSGLIGFFITFGIFMGKMGEKGKLMTDFFNILNEIIMKMVSMIMWYSPVGIASLICGKIAAIGDLEVVARQLGMYMVTVIVGLIIHGGIILPIIFFAVTRKNPFVFYSGIFQAWITALGTASSAGTLPVTFRCLEENLKIDKRVTRFVLPIGATINMDGTALYEAVAAIFIAQMNDIDLDGGQIATVS 395 HSP 2 Score: 83.9593 bits (206), Expect = 3.110e-99 Identity = 39/74 (52.70%), Postives = 58/74 (78.38%), Query Frame = 2
Query: 1280 ATFAAIGASCVPSSGLVTVIPALASVGLPISDITLILTVDWFLDRVRTTINVLGDSLGSGIIESLLENDKIEID 1501
AT A++GA+ +PS+GLVT++ L +VGLP DI+L++ VDW LDR+RT+INV+GDS G+GI++ L + +ID
Sbjct: 398 ATLASVGAASIPSAGLVTMLLILTAVGLPTQDISLLIAVDWLLDRMRTSINVVGDSFGAGIVDFLSRAELAQID 471
BLAST of slc1a-4 vs. Ensembl Cavefish
Match: slc1a2b (solute carrier family 1 member 2 [Source:NCBI gene;Acc:103022057]) HSP 1 Score: 297.36 bits (760), Expect = 6.563e-98 Identity = 177/374 (47.33%), Postives = 257/374 (68.72%), Query Frame = 1
Query: 214 GLLAGFFIKSTFIVNEYQIYLISFPGEXXXXXXXXXXXXXXXXXXXXXXXXXETKSSGKIGLYTVLYYGITTSISLIMGMVLVVTIHPGNPKIKNLQPLENTGP---TSNIGALESIFDLIRNIFPPNLIEGCFRQVATNYAIEKENIYKNFTEFPRNIS---------------KLTITMVESTNILGLVFFSITFGLILGQLGNKGKKMFQFFEVLNQVIMTMVTYIMWYFPXXXXXXXXXXXXXXXNLESAASSLGLYIMTVLLGLFIHGGIVLPLMYFIVCKKNPYWFFRALPQAWLASFGTASSTATLPITFKCLESNKLVSKKVTRFVLPIGATINMDGTALYEAVASIFIAQINGMVLSFGQIFSMS 1281
G ++G ++ +++ + +I+FPG++LM MLKMLILPL+ SSLITGL+ L+ KSSG++G ++YY TT I+ I+G++LV+ IHPGNPK+K EN G ++ +L++ FDLIRN+FP NL++ CF+Q+ T ++K + +F + + K ++ N+LGL+ F I FG+ +G++G K + M +FF +LN+++M +V IMWY P GI LI GKI+ IK+LE A LG+Y++TV++GL IHG I LP +YF + +KNP+ FF + QAW+ + GTASS TLP+TF+CLE N + K+VTRFVLP+GATINMDGTALYEAVA+IFIAQ+NG+VL GQI ++S
Sbjct: 48 GAVSGMLLRVASPIDDNIVMVIAFPGDILMRMLKMLILPLIISSLITGLAGLDAKSSGRLGTRAMVYYMTTTIIAAILGVILVLIIHPGNPKLK-----ENLGEGLQNDDVSSLDAFFDLIRNLFPENLVQACFQQIQT--VVKKVEVQPDFDDSNSTMDEFLSGATKPPPIFKQKKSLQFKSGMNVLGLIGFFIAFGICMGKMGEKARLMIEFFNILNEIVMKLVIMIMWYSPFGIACLICGKIISIKDLEVVARQLGMYMITVIVGLIIHGAIFLPCIYFAIVRKNPFTFFMGIFQAWITALGTASSAGTLPVTFRCLEENLGIDKRVTRFVLPVGATINMDGTALYEAVAAIFIAQMNGVVLDPGQIVTVS 414 HSP 2 Score: 80.8777 bits (198), Expect = 6.563e-98 Identity = 36/65 (55.38%), Postives = 52/65 (80.00%), Query Frame = 2
Query: 1280 ATFAAIGASCVPSSGLVTVIPALASVGLPISDITLILTVDWFLDRVRTTINVLGDSLGSGIIESL 1474
AT A++GA+ +PS+GLVT++ L +VGLP DI+L++ VDW LDR RT++NV+GDS G+GI+ L
Sbjct: 417 ATLASVGAASIPSAGLVTMLLILTAVGLPTQDISLLVAVDWLLDRFRTSVNVVGDSYGAGIVYHL 481
BLAST of slc1a-4 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000010766.1 (pep scaffold:Pmarinus_7.0:GL477422:6105:14255:1 gene:ENSPMAG00000009750.1 transcript:ENSPMAT00000010766.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 252.677 bits (644), Expect = 1.316e-79 Identity = 165/383 (43.08%), Postives = 240/383 (62.66%), Query Frame = 1
Query: 205 VFTGLLAGFFIKSTFIVNEYQIYLISFPGEXXXXXXXXXXXXXXXXXXXXXXXXXETKSSGKIGLYTVLYYGITTSISLIMGMVLVVTIHPGNPKIKNLQPLENTGPTSNIGALESIFDLIRNIFPPNLIEGCFRQVATNYAIEKENIYKNFTEFPRNISKLTITMVE--STN--------------------ILGLVFFSITFGLILGQLGNKGKKMFQFFEVLNQVIMTMVTYIMWYFPXXXXXXXXXXXXXXXNLESAASSLGLYIMTVLLGLFIHGGIVLPLMYFIVCKKNPYWFFRALPQAWLASFG-TASSTATLPITFKCLESNKLVSKKVTRFVLPIGATINMDGTALYEAVASIFIAQINGMVLSFGQIFSMSY 1284
V G+L G + + I +ISFPGE+LM MLKMLILPL+ SSLITGLS L+ +SSG++G ++YY T+ + I+G+VLV+ IHPG+P +K + E + + ++I DLIRN+FP NL++ C +Q ++ + + +S+ + T E STN L LV F I FG++LG++G++ M +FF +LN+++M ++ ++WY PIGI LI GKI E+ +L LG+Y++TV++GL IHG ++LPL+YF++ +KNP FF + Q+ + S TLP+TF+CLE N + K+VTRFVLP+GATINMDGTALYEAVA+IFIAQ+NG+VL GQI + Y
Sbjct: 1 VIMGVLLGVVFRRAGQLQPNTILIISFPGEILMRMLKMLILPLIISSLITGLSGLDAQSSGRMGCRALVYYMATSVTAAILGIVLVLAIHPGDPSLKPDKGHEEE--LQAVSSFDAILDLIRNVFPENLVQACMQQ--QDFGLHGRHERSGSANVRVTLSERSPTGREKNSTNQVTEQRGGCISAGEHVIGTATLRLVCFVIAFGVVLGKMGDEATPMLKFFSILNEIVMRLIIIVIWYSPIGIASLICGKIAELSDLHVVMRQLGMYMLTVIVGLLIHGAVILPLVYFVITRKNPLKFFVGIFQSLTDARALCGRSAGTLPVTFRCLEENLKIDKRVTRFVLPVGATINMDGTALYEAVAAIFIAQMNGVVLDGGQIVVVRY 379
BLAST of slc1a-4 vs. Ensembl Sea Lamprey
Match: slc1a4 (solute carrier family 1 member 4 [Source:ZFIN;Acc:ZDB-GENE-030616-566]) HSP 1 Score: 215.312 bits (547), Expect = 1.216e-69 Identity = 148/344 (43.02%), Postives = 215/344 (62.50%), Query Frame = 1
Query: 280 SFPGEXXXXXXXXXXXXXXXXXXXXXXXXXETKSSGKIGLYTVLYYGITTSISLIMGMVLVVTIHPGNPKIKNLQPLENTG----PTSNIGALESIFDLI-RNIFPPNLIEGCFRQVATNYAIEKENIYKNFT------EFPRNISKLTITMVESTNILGLVFFSITFGLILGQLGNKGKKMFQFFEVLNQVIMTMVTYIMWYFPXXXXXXXXXXXXXXXNLESAASSLGLYIMTVLLGLFIHGGIVLPLMYFIVCKKNPYWFFRALPQAWLASFGTASSTATLPITFKCLESNKLVSKKVTRFVLPIGATINMDGTALYEAVASIFIAQINGMVLSFGQIFSM 1278
SFPGE+L+ MLKM+I+PL+ SL++G + L+ +S G++G +L++ +TT I+ +G+ + PG +K P TG P S A++S DL RNIFP NL+ F+ AT Y E I N T E + + + NILGLV F+I FG+ L +LG +G+ + FF N+ M +V++IMWY P+GI FL+ KI+E+ +L SSLG YI+ +LG +HGGI+LPL+YF ++NPY F + +FGTASS+ATLP+ KC+E N V KK++RF+LPIGAT+NMDG AL++ VA++FIA +N + L GQIF++
Sbjct: 16 SFPGELLIRMLKMIIIPLVVCSLVSGAASLDPRSLGRLGGLAILFFLVTTLIASSVGVAFAFMLKPGAGGVK---PAVYTGAVALPQSK-EAVDSFLDLASRNIFPANLVSAAFQSYATTY--ETVFIKMNLTTENGTMEIIKQEKVPVGSDADGMNILGLVMFAICFGIALRKLGPEGEALIGFFNSFNEATMVLVSWIMWYAPLGIMFLVASKIVEMDDLVQLISSLGKYILCCILGHAMHGGIILPLIYFACTRQNPYRFLLGIITPLTTAFGTASSSATLPLMIKCIEENNGVDKKISRFILPIGATVNMDGAALFQCVAAVFIAYMNNVTLDAGQIFTI 353 HSP 2 Score: 66.2402 bits (160), Expect = 1.216e-69 Identity = 32/70 (45.71%), Postives = 51/70 (72.86%), Query Frame = 2
Query: 1280 ATFAAIGASCVPSSGLVTVIPALASVGLPISDITLILTVDWFLDRVRTTINVLGDSLGSGIIESLLENDK 1489
AT +++GA+ +P+ G++T+ L +V LP +DI+LIL VDW +DR T INV GD++G+GI+ L + D+
Sbjct: 357 ATASSVGAAGIPAGGVLTLAIILEAVSLPTNDISLILAVDWLVDRTCTVINVEGDAIGAGILHVLSQRDQ 426
BLAST of slc1a-4 vs. Ensembl Sea Lamprey
Match: SLC1A2 (solute carrier family 1 member 2 [Source:HGNC Symbol;Acc:HGNC:10940]) HSP 1 Score: 160.229 bits (404), Expect = 2.670e-46 Identity = 94/234 (40.17%), Postives = 142/234 (60.68%), Query Frame = 1
Query: 445 MGMVLVVTIHPGNPKIKNLQPLENTGPTSNIGALESIFDLIRNIFPPNLIEGCFRQVATNYAIEKENIYKN----------FTEFPRNISKLTITM---------VESTNILGLVFFSITFGLILGQLGNKGKKMFQFFEVLNQVIMTMVTYIMWYFPXXXXXXXXXXXXXXXNLESAASSLGLYIMTVLLGLFIHGGIVLPLMYFIVCKKNPYWFFRALPQAWLASFGTASST 1089
+G++LV+ IHPGNPK+K + L + +L++ DLIRN+FP NL++ CF+QV T +I + + P ++ IT+ S L+ F I FG+I+G++G++ K M +FF +LN++IM +V IMWY P GI LI GKI +IK+LE A LG+Y++TV++GL IHG I+LPL+YF + +KNP+ FF + QAW+ + GTAS +
Sbjct: 1 LGVILVLAIHPGNPKLK--KQLGKGQLNEEVSSLDAFLDLIRNLFPENLVQACFQQVWTISSIRSAMVLCAPRAVAVGNGVSADLPAAHREMRITLPLMSLIPANTPSYWATRLIGFFIAFGIIMGKMGDQAKLMVEFFSILNEIIMRLVIMIMWYSPFGIASLICGKISDIKDLEVVARQLGMYMITVIVGLIIHGAIILPLIYFSITRKNPFKFFVGIFQAWITALGTASRS 232
BLAST of slc1a-4 vs. Ensembl Sea Lamprey
Match: SLC1A2 (solute carrier family 1 member 2 [Source:HGNC Symbol;Acc:HGNC:10940]) HSP 1 Score: 104.375 bits (259), Expect = 6.013e-42 Identity = 46/66 (69.70%), Postives = 57/66 (86.36%), Query Frame = 1
Query: 1084 STATLPITFKCLESNKLVSKKVTRFVLPIGATINMDGTALYEAVASIFIAQINGMVLSFGQIFSMS 1281
S TLP+TF+CLE N + K++TRFVLP+GATINMDGTALYEAVA+IFIAQ+NG+VL GQI ++S
Sbjct: 1 SAGTLPVTFRCLEENLGIDKRITRFVLPVGATINMDGTALYEAVAAIFIAQMNGVVLDGGQIVTVS 66 HSP 2 Score: 84.7297 bits (208), Expect = 6.013e-42 Identity = 41/82 (50.00%), Postives = 60/82 (73.17%), Query Frame = 2
Query: 1280 ATFAAIGASCVPSSGLVTVIPALASVGLPISDITLILTVDWFLDRVRTTINVLGDSLGSGIIESLLENDKIEIDWINNSDLD 1525
AT A++GA+ +PS+GLVT++ L +VGLP SDI+L++ VDW LDR+RT++NV+GDS G+GI+ L + ID + D D
Sbjct: 69 ATLASVGAASIPSAGLVTMLLILTAVGLPTSDISLLVAVDWLLDRMRTSVNVVGDSFGAGIVYHLSRAELDAIDARAHEDPD 150
BLAST of slc1a-4 vs. Ensembl Sea Lamprey
Match: slc1a1 (solute carrier family 1 member 1 [Source:ZFIN;Acc:ZDB-GENE-040718-414]) HSP 1 Score: 148.288 bits (373), Expect = 1.092e-40 Identity = 127/331 (38.37%), Postives = 192/331 (58.01%), Query Frame = 1
Query: 118 KRSNTMRKIHLKKFLSNNENILFVLTVFSVFTGLLAGFFIKSTFIVNEYQIYLISFPGEXXXXXXXXXXXXXXXXXXXXXXXXXETKSSGKIGLYTVLYYGITTSISLIMGMVLVVTIHPGNPKIKNLQPLENTGPTSNIGALESIFDLIRNIFPPNLIEGCFRQVATNYA-IEKENIYKNFTEFP----------RNIS-----KLTITMVESTNILGLVFFSITFGLILGQLGNKGKKMFQFFEVLNQVIMTMVTYIMWYFPXXXXXXXXXXXXXXXNLESAASSLGLYIMTVLLG--LFIHGGIVLPLMYFIVCKKNPYWFFRALPQA 1056
+R+ T +I KK I+ T V TG+ G ++ N I SFPG++LM MLK++ILPL+ SS+ITGL+ L++ SGKIG V YY TT +++++G+ LV+ I PG + + ++ TG T N ++++ DL+RN+FP NL++ CF+Q T + I+ E + N T P N++ +LT N+LGL+ F + FG ++ ++G G+ + FF+ LN+ M +V IMWY PIGIFFL+ GKI+E+ + E LGLY+ TVL G L IH +VLPL+YFIV ++NP+ + L A
Sbjct: 6 RRNCTEHRIIRKK-------IVICGTAICVGTGIGTGLLLREFANFNSLDIVYFSFPGDVLMRMLKLIILPLIVSSMITGLASLDSNVSGKIGGLAVAYYLSTTVLAVLLGIALVLLIKPGVSQ--STDEIDRTGSTPNATTVDTLLDLVRNMFPENLVQACFQQYRTRRSEIDPEVVIVNSTASPVTTTLSMALSTNVTVIKEFRLTGEYSSGINVLGLIVFCVAFGSVIRRMGPSGEILAAFFDALNEATMRIVAIIMWYMPIGIFFLVAGKIMEVDDWE-IFRKLGLYMATVLSGSSLAIHSLVVLPLIYFIVVRRNPFSYIAGLTHA 326
BLAST of slc1a-4 vs. Ensembl Nematostella
Match: EDO39457 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S9W7]) HSP 1 Score: 228.409 bits (581), Expect = 3.625e-81 Identity = 158/422 (37.44%), Postives = 244/422 (57.82%), Query Frame = 1
Query: 151 KKFLSNNENILFVLTVFSVFTGLLAGFFIKSTFIVN------------EYQIYLISFPGEXXXXXXXXXXXXXXXXXXXXXXXXXETKSSGKIGLYTVLYYGITTSISLIMGMVLVVTIHPGN---PKIKNLQPLENTGPTSNIGALESIFDLIRNIFPPNLIEGCFRQVATNYA------------IEKENIYK--------------NFTEFPRNISKLTITMV--------ESTNILGLVFFSITFGLILGQLGNKGKKMFQFFEVLNQVIMTMVTYIMWYFPXXXXXXXXXXXXXXXNLESAASSLGLYIMTVLLGLFIHGGIVLPLMYFIVCKKNPYWFFRALPQAWLASFGTASSTATLPITFKCLESNKLVSKKVTRFVLPIGATINMDGTALYEAVASIFIAQINGMVLSFGQI 1269
+K++ +N L VF +F G+L GF I F+VN + I LI FPGE+ MNMLK+L++PL+ +S+I L+ L+ +SS ++ T +YY TT +++I+G+VLV + PG+ P+ K L+P S L+++ DLIR+ FP N+I F Q T+Y + N+ + N+T P+ I + T+ E+ NILGL+ FS+ FG +LG++G +G + FE LN+VI+ M+ +MW+ PIG+ LI ++ ++++ + S LGLY+ TV+ GL H +LPL++ I ++NP F + A L +FGT+SSTATLP T +CLE V +++RFVLP+G+T+NMDGTALYE VA++FIAQI+G+ L +
Sbjct: 1 RKWIHSN------LLVFLIFIGILLGFVIG--FLVNSPLKNLRSDEDRKTNIMLIGFPGELFMNMLKLLMVPLVVASVICALAALDGRSSNRVSRRTFVYYLATTLLAVIIGVVLVTFMKPGSYGKPEGKGLKP-------SFYRPLDAVLDLIRSCFPSNIITAAFMQQRTHYTSTAAKVSYVNRTVNVHNMSQAELNSMRILSNGTHNYTTTPQAIRAASNTVPDGSKADSGENANILGLLVFSLVFGAVLGRMGERGVPLKALFESLNEVILKMLALVMWFAPIGVCSLIAAQMASMEDIMGSLSMLGLYMATVIAGLLAHALFILPLLFIIATRRNPLTFICGMRDALLTAFGTSSSTATLPCTIRCLEDRNRVDARISRFVLPLGSTVNMDGTALYEVVAAVFIAQIHGIELGLDDL 407 HSP 2 Score: 92.4337 bits (228), Expect = 3.625e-81 Identity = 42/81 (51.85%), Postives = 62/81 (76.54%), Query Frame = 2
Query: 1280 ATFAAIGASCVPSSGLVTVIPALASVGLPISDITLILTVDWFLDRVRTTINVLGDSLGSGIIESLLENDKIEIDWINNSDL 1522
AT A+IGAS +P +GLVT++ L +V LP DI LIL+VDWF+DR+RTT+NVLGD++G+GI+E L +D + +D+ ++
Sbjct: 414 ATAASIGASGIPQAGLVTMVMVLTAVNLPTEDIGLILSVDWFIDRIRTTVNVLGDAIGAGIVEHLSRDDLMNLDYTTREEV 494
BLAST of slc1a-4 vs. Ensembl Nematostella
Match: EDO37906 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SED2]) HSP 1 Score: 237.269 bits (604), Expect = 8.221e-77 Identity = 132/309 (42.72%), Postives = 196/309 (63.43%), Query Frame = 1
Query: 370 ETKSSGKIGLYTVLYYGITTSISLIMGMVLVVTIHPGN---PKIKNLQPLENTGPTSNIGALESIFDLIRNIFPPNLIEGCFRQVATNYAIEKENIYKNFTEFPRNISKLTITMVES------TNILGLVFFSITFGLILGQLGNKGKKMFQFFEVLNQVIMTMVTYIMWYFPXXXXXXXXXXXXXXXNLESAASSLGLYIMTVLLGLFIHGGIVLPLMYFIVCKKNPYWFFRALPQAWLASFGTASSTATLPITFKCLESNKLVSKKVTRFVLPIGATINMDGTALYEAVASIFIAQINGMVLSFGQI 1269
++ ++GKIG TVLYY TT I++++G+ +V I PG PK + ++ ++ GP N L+S DLIR++FP N++E F Q+ K N N T I + T+ + N+LG+V FSI FG++LG++G +G + FFE LN+VIM M+T +MW PIGI LI ++++ ++ SA +LG++I T L L IHG ++LPL+YFI ++NP+ + L A + +FGT SS+ATLP T +C E V K++ RFVLP+GAT+NMDGTALYE V ++IAQ+NG+ L G+I
Sbjct: 24 DSSATGKIGRRTVLYYLCTTLIAVLLGIAMVSIIQPGKGDKPKGERIE--QSAGPRRN---LDSFLDLIRSLFPNNIVEATFMQMEYRIRNAKINGTHNITTLRNTIYGPSETIPDGYSRTWGLNVLGIVMFSIVFGIVLGRMGERGAPLKSFFETLNEVIMQMITIVMWLSPIGICSLIAKNLVQMGDIPSAFKALGMFIGTSLAALLIHGLVILPLVYFICTRRNPFKYMFNLVDALVTAFGTDSSSATLPTTIRCCEEENHVDKRIVRFVLPLGATVNMDGTALYEGVCCLWIAQMNGIELGPGEI 327 HSP 2 Score: 68.9366 bits (167), Expect = 8.221e-77 Identity = 30/54 (55.56%), Postives = 42/54 (77.78%), Query Frame = 2
Query: 1313 PSSGLVTVIPALASVGLPISDITLILTVDWFLDRVRTTINVLGDSLGSGIIESL 1474
PS+GLVT++ L +VGLP DI LI +VDWF+DR RT +N+ GD+ G+G++E L
Sbjct: 345 PSAGLVTMLIVLQAVGLPTDDIALIWSVDWFIDRFRTMVNITGDAYGAGVVEHL 398
BLAST of slc1a-4 vs. Ensembl Nematostella
Match: EDO33620 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SRP9]) HSP 1 Score: 210.69 bits (535), Expect = 9.073e-62 Identity = 141/370 (38.11%), Postives = 225/370 (60.81%), Query Frame = 1
Query: 256 NEYQIYLISFPGEXXXXXXXXXXXXXXXXXXXXXXXXXETKSSGKIGLYTVLYYGITTSISLIMGMVLVVTIHPGNPKIKNLQPLENTGPTSNIGALESIFDLIRNIFPPNLIEGCFRQVATNYAIEK-ENIYKNFTEFPRNI-SKLTITMVES----------------------------TNILGLVFFSITFGLILGQLGNKGKKMFQFFEVLNQVIMTMVTYIMWYFPXXXXXXXXXXXXXXXNLESAASSLGLYIMTVLLGLFIHGGIVLPLMYFIVCKKNPYWFFRALPQAWLASFGTASSTATLPITFKCLESNKLVSKKVTRFVLPIGATINMDGTALYEAVASIFIAQINGMVLSFGQIFS 1275
+ I LI FPGE+ MNMLK++ILPL+ +SLI+ L+ ++ K++GKIG +L+Y +TT + I+G++LV+ I PG + ++P+E G + ++S DL+R++FP N++E CF Q T YA + + + N TE +I S++T T++ + TN+LG+ F + FG+IL ++G K + + FF LN +M +V IMW PIGI ++ K+ E+ ++ S +G +++TV+ + IHG VLPLMYF++ +KNPY F + A + +FG +SS+ATLP T +C E V +++ +FVLP+GAT+NMDG AL+E+ IFIAQING+ + +F+
Sbjct: 59 RKTTIMLIGFPGELFMNMLKLVILPLIVASLISALACMDPKATGKIGRRVLLFYFLTTISAAILGLILVLAIRPG----RVVKPVEKQGQPVSYRTMDSFLDLLRSLFPNNIVEACFIQYKTKYAYDPGKYMSYNTTENITSITSRVTTTIISNGTHNITTVVKEVYPPSNLIPSGRQASSGTNVLGIAMFCLVFGIILSRMGAKAEPLRAFFCSLNDAVMRLVMIIMWLSPIGICSIVAAKVGEMGDIVGVLSMVGYFMLTVISSILIHGLFVLPLMYFVMTRKNPYKFMLGMGDALVTAFGISSSSATLPTTIRCAEETG-VDERIAKFVLPLGATVNMDGGALFESCVVIFIAQINGVPMEAAFLFN 423 HSP 2 Score: 75.0998 bits (183), Expect = 1.873e-14 Identity = 34/90 (37.78%), Postives = 59/90 (65.56%), Query Frame = 2
Query: 1241 MEWYYLLDKYFL*ATFAAIGASCVPSSGLVTVIPALASVGLPISDITLILTVDWFLDRVRTTINVLGDSLGSGIIESLLENDKIEIDWIN 1510
ME +L + + A ++GA+ +PS+G + + L SVGLP+ D+ L+L ++W LDR RTT+NV GD++G+GI+ + + D + +D +
Sbjct: 416 MEAAFLFNTVLM-AAAISVGAAGIPSAGFIYPVIVLQSVGLPVEDLALVLPIEWLLDRFRTTVNVWGDAVGAGIVNHMSKADLVAMDALQ 504
BLAST of slc1a-4 vs. Ensembl Nematostella
Match: EDO32707 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SUA1]) HSP 1 Score: 194.512 bits (493), Expect = 1.408e-61 Identity = 107/251 (42.63%), Postives = 156/251 (62.15%), Query Frame = 1
Query: 562 LIRNIFPPNLIEGCFRQVATNYAIE---KENIYKNFTEFPRNISKLTITMVE------------STNILGLVFFSITFGLILGQLGNKGKKMFQFFEVLNQVIMTMVTYIMWYFPXXXXXXXXXXXXXXXNLESAASSLGLYIMTVLLGLFIHGGIVLPLMYFIVCKKNPYWFFRALPQAWLASFGTASSTATLPITFKCLESNKLVSKKVTRFVLPIGATINMDGTALYEAVASIFIAQINGMVLSFGQI 1269
L R +FPPN+ E F QV+TN + I+ N T I +L + S N+LGLV FSI G +L ++G+KG + FF+ LN V+M MVT +MWY P+GI LI K+ + ++ + LG++++T +LG+ +H I LP++Y+++ KKNP+ F + + A + +GTASS ATLP T +C E N + ++TRFVLP+GAT+NMDGTALYE V +I+IAQIN + L+ GQI
Sbjct: 1 LHRQVFPPNIAEATFNQVSTNTIKQVFFTIKIFSNGTHNLTTIRQLVHRAYDQIPGGTFPTPGSSMNVLGLVMFSIVLGAMLSKMGDKGLPLKCFFQALNDVVMRMVTLVMWYSPVGICSLIASKVAGMGDIALSLKLLGMFMLTSILGILLHTLITLPIIYYVMTKKNPFKFMKGMSDALVTVWGTASSAATLPTTIRCAEENNGLDSRITRFVLPLGATVNMDGTALYEGVGAIWIAQINNIPLTAGQI 251 HSP 2 Score: 60.8474 bits (146), Expect = 1.408e-61 Identity = 26/59 (44.07%), Postives = 41/59 (69.49%), Query Frame = 2
Query: 1310 VPSSGLVTVIPALASVGLPISDITLILTVDWFLDRVRTTINVLGDSLGSGIIESLLEND 1486
VPS+GL+T++ ++ +P DI LI VDWF+DR R N++GDS G+GI++ L + +
Sbjct: 268 VPSAGLITMVIVCQAINVPPDDIGLIFAVDWFIDRFRGLPNIMGDSYGAGIVQHLSKEE 326
BLAST of slc1a-4 vs. Ensembl Nematostella
Match: EDO28941 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T521]) HSP 1 Score: 83.9593 bits (206), Expect = 1.156e-28 Identity = 38/62 (61.29%), Postives = 48/62 (77.42%), Query Frame = 1
Query: 1084 STATLPITFKCLESNKLVSKKVTRFVLPIGATINMDGTALYEAVASIFIAQINGMVLSFGQI 1269
S ATLP T +C E N + ++TRFVLP+GAT+NMDGTALYE V +I+IAQIN + L+ GQI
Sbjct: 16 SAATLPTTIRCAEENNGLDSRITRFVLPLGATVNMDGTALYEGVGAIWIAQINNIPLTAGQI 77 HSP 2 Score: 61.2326 bits (147), Expect = 1.156e-28 Identity = 26/59 (44.07%), Postives = 42/59 (71.19%), Query Frame = 2
Query: 1310 VPSSGLVTVIPALASVGLPISDITLILTVDWFLDRVRTTINVLGDSLGSGIIESLLEND 1486
VPS+GL+T++ ++ +P DI LI VDWF+DR R N++GDS G+GI++ L +++
Sbjct: 94 VPSAGLITMVIVCQAINVPPDDIGLIFAVDWFIDRFRGLPNIMGDSYGAGIVQHLSKDE 152
BLAST of slc1a-4 vs. Ensembl Medaka
Match: slc1a2a (excitatory amino acid transporter 2-like [Source:NCBI gene;Acc:101160301]) HSP 1 Score: 316.235 bits (809), Expect = 1.207e-103 Identity = 186/374 (49.73%), Postives = 264/374 (70.59%), Query Frame = 1
Query: 172 ENILFVLTVFSVFTGLLAGFFIKSTFIVNEYQIYLISFPGEXXXXXXXXXXXXXXXXXXXXXXXXXETKSSGKIGLYTVLYYGITTSISLIMGMVLVVTIHPGNPKIKNLQPLENTG---PTSNIGALESIFDLIRNIFPPNLIEGCFRQVATNYAIEKENIYKNFTEFPRNIS-KLTITMVESTNILGLVFFSITFGLILGQLGNKGKKMFQFFEVLNQVIMTMVTYIMWYFPXXXXXXXXXXXXXXXNLESAASSLGLYIMTVLLGLFIHGGIVLPLMYFIVCKKNPYWFFRALPQAWLASFGTASSTATLPITFKCLESNKLVSKKVTRFVLPIGATINMDGTALYEAVASIFIAQINGMVLSFGQIFSMS 1281
+N++ LT+ VF G +AG ++ + I +I+FPGE+LM MLKMLILPL+ SSL+TGL+ L+ KSSG++G ++YY TT I+ ++G++LV+ IHPGNPK++ N G + ++++ FDLIRN+FP NL++ CF+Q+ T I K + N T P + K ++ N+LGL+ F + FG+I+G++G K K M +FF VLN+++M +V IMWY P GI LI GKI+ I +LE A LG+Y++TV++GL IHGGI LPL+YF++ KKNP+ FF + QAW+ + GTASS TLP+TF+CLE N + K+VTRFVLP+GATINMDGTALYEAVA+IFIAQ+NG+ L +GQI ++S
Sbjct: 34 KNMVLTLTILGVFLGSIAGMLLRHISPLPPDVIMIIAFPGEILMRMLKMLILPLVVSSLVTGLAGLDAKSSGRLGTRAMVYYMSTTVIAAVLGVILVLLIHPGNPKLR-----ANLGLGKKNDEVSSVDAFFDLIRNLFPENLVQACFQQIQT--VITKVQVPTNRTRAPPQFTIKRSLQFKSGMNVLGLIGFFVAFGVIMGKMGEKAKLMLEFFNVLNEIVMKLVGAIMWYSPFGIACLICGKIISIADLEVVARQLGMYMVTVIVGLIIHGGIFLPLIYFVIVKKNPFTFFMGIFQAWVTALGTASSAGTLPVTFRCLEENLGIDKRVTRFVLPVGATINMDGTALYEAVAAIFIAQMNGIDLDWGQIITVS 400 HSP 2 Score: 80.8777 bits (198), Expect = 1.207e-103 Identity = 36/69 (52.17%), Postives = 55/69 (79.71%), Query Frame = 2
Query: 1280 ATFAAIGASCVPSSGLVTVIPALASVGLPISDITLILTVDWFLDRVRTTINVLGDSLGSGIIESLLEND 1486
AT A++GA+ +PS+GLVT++ L +VGLP DI+L++ VDW LDR RT++NV+GDS G+GI+ L +++
Sbjct: 403 ATLASVGAASIPSAGLVTMLLILTAVGLPTQDISLLVAVDWLLDRFRTSVNVVGDSYGAGIVYHLSKDE 471
BLAST of slc1a-4 vs. Ensembl Medaka
Match: slc1a2b (solute carrier family 1 member 2 [Source:NCBI gene;Acc:101170755]) HSP 1 Score: 295.819 bits (756), Expect = 5.067e-98 Identity = 179/371 (48.25%), Postives = 257/371 (69.27%), Query Frame = 1
Query: 214 GLLAGFFIKSTFIVNEYQIYLISFPGEXXXXXXXXXXXXXXXXXXXXXXXXXETKSSGKIGLYTVLYYGITTSISLIMGMVLVVTIHPGNPKIKNLQPLENTGP---TSNIGALESIFDLIRNIFPPNLIEGCFRQVATN----YAIEKE--------NIYKNFTEFPRNISKLTITMVESTNILGLVFFSITFGLILGQLGNKGKKMFQFFEVLNQVIMTMVTYIMWYFPXXXXXXXXXXXXXXXNLESAASSLGLYIMTVLLGLFIHGGIVLPLMYFIVCKKNPYWFFRALPQAWLASFGTASSTATLPITFKCLESNKLVSKKVTRFVLPIGATINMDGTALYEAVASIFIAQINGMVLSFGQIFSMS 1281
G ++G ++ ++ + +I+FPG++LM MLKMLILPL+ SSLITGL+ L+ KSSG++G ++YY TT I+ ++G++LV+ IHPGNPK+K EN G ++ +L++ FDLIRN+FP NL++ CF+Q+ T IE+E + N T P+ I K ++ N+LGL+ F I FG+ +G++G + + M +FF +LN+++M +V IMWY P GI LI GKI+ IK+LE A LG+Y++TV++GL IHG I LP +YF + +KNP+ FF + QAW+ + GTASS TLP+TF+CLE N + K+VTRFVLP+GATINMDGTALYEAVA+IFIAQ+NG+ L GQI ++S
Sbjct: 53 GAVSGMLLRVASPIHPDIVMVIAFPGDILMRMLKMLILPLIISSLITGLAGLDAKSSGRLGTRAMVYYMTTTVIAAVLGVILVLLIHPGNPKLK-----ENLGEGEKNEDVSSLDAFFDLIRNLFPENLVQACFQQIQTVTKKVEVIEEEVNTTTSMGGLLVNITHEPQYIVKKSLQFKSGMNVLGLIGFFIAFGICMGKMGERARLMIEFFNILNEIVMKLVIMIMWYSPFGIACLICGKIISIKDLEVVARQLGMYMITVIIGLIIHGVIFLPSIYFAITRKNPFTFFLGIFQAWITALGTASSAGTLPVTFRCLEENLGIDKRVTRFVLPVGATINMDGTALYEAVAAIFIAQMNGVHLDPGQIVTVS 418 HSP 2 Score: 82.8037 bits (203), Expect = 5.067e-98 Identity = 38/74 (51.35%), Postives = 57/74 (77.03%), Query Frame = 2
Query: 1280 ATFAAIGASCVPSSGLVTVIPALASVGLPISDITLILTVDWFLDRVRTTINVLGDSLGSGIIESLLENDKIEID 1501
AT A++GA+ +PS+GLVT++ L +VGLP DI+L++ VDW LDR RT++NV+GDS G+GI+ L + + E+D
Sbjct: 421 ATLASVGAASIPSAGLVTMLLILTAVGLPTQDISLLVAVDWLLDRFRTSVNVVGDSYGAGIVYHLSKAELDELD 494
BLAST of slc1a-4 vs. Ensembl Medaka
Match: slc1a2b (solute carrier family 1 member 2 [Source:NCBI gene;Acc:101170755]) HSP 1 Score: 295.434 bits (755), Expect = 7.488e-98 Identity = 179/371 (48.25%), Postives = 257/371 (69.27%), Query Frame = 1
Query: 214 GLLAGFFIKSTFIVNEYQIYLISFPGEXXXXXXXXXXXXXXXXXXXXXXXXXETKSSGKIGLYTVLYYGITTSISLIMGMVLVVTIHPGNPKIKNLQPLENTGP---TSNIGALESIFDLIRNIFPPNLIEGCFRQVATN----YAIEKE--------NIYKNFTEFPRNISKLTITMVESTNILGLVFFSITFGLILGQLGNKGKKMFQFFEVLNQVIMTMVTYIMWYFPXXXXXXXXXXXXXXXNLESAASSLGLYIMTVLLGLFIHGGIVLPLMYFIVCKKNPYWFFRALPQAWLASFGTASSTATLPITFKCLESNKLVSKKVTRFVLPIGATINMDGTALYEAVASIFIAQINGMVLSFGQIFSMS 1281
G ++G ++ ++ + +I+FPG++LM MLKMLILPL+ SSLITGL+ L+ KSSG++G ++YY TT I+ ++G++LV+ IHPGNPK+K EN G ++ +L++ FDLIRN+FP NL++ CF+Q+ T IE+E + N T P+ I K ++ N+LGL+ F I FG+ +G++G + + M +FF +LN+++M +V IMWY P GI LI GKI+ IK+LE A LG+Y++TV++GL IHG I LP +YF + +KNP+ FF + QAW+ + GTASS TLP+TF+CLE N + K+VTRFVLP+GATINMDGTALYEAVA+IFIAQ+NG+ L GQI ++S
Sbjct: 48 GAVSGMLLRVASPIHPDIVMVIAFPGDILMRMLKMLILPLIISSLITGLAGLDAKSSGRLGTRAMVYYMTTTVIAAVLGVILVLLIHPGNPKLK-----ENLGEGEKNEDVSSLDAFFDLIRNLFPENLVQACFQQIQTVTKKVEVIEEEVNTTTSMGGLLVNITHEPQYIVKKSLQFKSGMNVLGLIGFFIAFGICMGKMGERARLMIEFFNILNEIVMKLVIMIMWYSPFGIACLICGKIISIKDLEVVARQLGMYMITVIIGLIIHGVIFLPSIYFAITRKNPFTFFLGIFQAWITALGTASSAGTLPVTFRCLEENLGIDKRVTRFVLPVGATINMDGTALYEAVAAIFIAQMNGVHLDPGQIVTVS 413 HSP 2 Score: 82.8037 bits (203), Expect = 7.488e-98 Identity = 38/74 (51.35%), Postives = 57/74 (77.03%), Query Frame = 2
Query: 1280 ATFAAIGASCVPSSGLVTVIPALASVGLPISDITLILTVDWFLDRVRTTINVLGDSLGSGIIESLLENDKIEID 1501
AT A++GA+ +PS+GLVT++ L +VGLP DI+L++ VDW LDR RT++NV+GDS G+GI+ L + + E+D
Sbjct: 416 ATLASVGAASIPSAGLVTMLLILTAVGLPTQDISLLVAVDWLLDRFRTSVNVVGDSYGAGIVYHLSKAELDELD 489
BLAST of slc1a-4 vs. Ensembl Medaka
Match: SLC1A3 (solute carrier family 1 member 3 [Source:NCBI gene;Acc:101170607]) HSP 1 Score: 277.33 bits (708), Expect = 5.817e-95 Identity = 176/413 (42.62%), Postives = 269/413 (65.13%), Query Frame = 1
Query: 118 KRSNTMRKIHLKKFLSNNENILFVLTVFSVFTGLLAGFFIKSTFIVNEYQIYLISFPGEXXXXXXXXXXXXXXXXXXXXXXXXXETKSSGKIGLYTVLYYGITTSISLIMGMVLVVTIHPGN---PKIKNLQPLENTGPTSNIGALESIFDLIRNIFPPNLIEGCFRQVATNYA-------IEKENIYKNFTEFPRNISKLTIT-------MVESTNILGLVFFSITFGLILGQLGNKGKKMFQFFEVLNQVIMTMVTYIMWYFPXXXXXXXXXXXXXXXNLESAASSLGLYIMTVLLGLFIHGGIVLPLMYFIVCKKNPYWFFRALPQAWLASFGTASSTATLPITFKCLESNKLVSKKVTRFVLPIGATINMDGTALYEAVASIFIAQINGMVLSFGQIFSMSYICSNWSL 1305
++ + K ++ F N +LF TV +V G++ GF ++ + ++ ++ SFPGE+LM ML+ML+LPLL SSLITG++ L++K+SGK+G+ V+YY TT I++ +G+++V+ IHPG + Q +E P ++ DLIRN+FPPNL++ C +Q T Y + + + N T + + ++T V N LGLV FS+ FGLI+G + +G+ + +FF+ LN+ IM +V IMWY PIGI FLI GKI+E+ +L LG+Y +TV++GL IH ++LP++YF++ ++NP+ F L QA + + GT+SS+ATLP+TFKCLE N + K++TRFVLP+GATINMDGTALYEA+A+IFIAQ+N M ++FGQI ++S + S+
Sbjct: 17 RKVEEISKEDVQAFFKKNAFVLF--TVAAVVLGVILGFSLRP-YKMSYREVKYFSFPGEVLMRMLQMLVLPLLVSSLITGMAALDSKASGKMGMRAVIYYMTTTIIAVFIGILIVLIIHPGKGSKAEFGKQQTIEQISPA------DAFLDLIRNMFPPNLVQACTQQFKTKYGKRTVHLTVTINDTFFNSTNNTQEVMEITREEMIPIPGQVNGLNALGLVVFSMCFGLIIGNMKEQGQLLREFFDGLNEAIMQLVAIIMWYAPIGILFLIAGKIVEMDDLTQMGGQLGMYTITVIIGLMIHAVLILPMLYFVITRQNPFVFIAGLLQALVTALGTSSSSATLPVTFKCLEENNKIDKRITRFVLPVGATINMDGTALYEALAAIFIAQVNNMEMNFGQIITISITATAASI 420 HSP 2 Score: 91.2781 bits (225), Expect = 5.817e-95 Identity = 44/69 (63.77%), Postives = 56/69 (81.16%), Query Frame = 2
Query: 1280 ATFAAIGASCVPSSGLVTVIPALASVGLPISDITLILTVDWFLDRVRTTINVLGDSLGSGIIESLLEND 1486
AT A+IGA+ +P +GLVT++ L SVGLP DITLI+ VDWFLDR+RTT NVLGDS+G+GIIE L ++
Sbjct: 415 ATAASIGAAGIPQAGLVTMVIVLTSVGLPTDDITLIIAVDWFLDRLRTTTNVLGDSIGAGIIEFLSRHE 483
BLAST of slc1a-4 vs. Ensembl Medaka
Match: slc1a9 (excitatory amino acid transporter 2 [Source:NCBI gene;Acc:101167791]) HSP 1 Score: 280.796 bits (717), Expect = 8.718e-94 Identity = 173/363 (47.66%), Postives = 252/363 (69.42%), Query Frame = 1
Query: 214 GLLAGFFIKSTFIVNEYQIYLISFPGEXXXXXXXXXXXXXXXXXXXXXXXXXETKSSGKIGLYTVLYYGITTSISLIMGMVLVVTIHPGNPKIKNLQPLENTGPTSNIGALESIFDLIRNIFPPNLIEGCFRQVATNYAIEKENIYKNFTEFPRNISKLTITMVEST-------NILGLVFFSITFGLILGQLGNKGKKMFQFFEVLNQVIMTMVTYIMWYFPXXXXXXXXXXXXXXXNLESAASSLGLYIMTVLLGLFIHGGIVLPLMYFIVCKKNPYWFFRALPQAWLASFGTASSTATLPITFKCLESNKLVSKKVTRFVLPIGATINMDGTALYEAVASIFIAQINGMVLSFGQIFSMS 1281
G++ G ++ + + + ++SFPGE+LM MLKMLILPL+ SSLITGL+ L+ +SSG++G ++YY TT I+ ++G++LV+ IHPGNPK++ T + +L++ DLIRN+FP NL++ C +QV T P N S+ +++V+ N+LGL+ F ITFG+ +G++G +GK M FF +LN++IMTMV+ IMWY P+GI LI GKI I +LE+ A LG+Y++TV++GL IHGG++LP ++F + +K+P+ F+ + QAW+ + GTASS TLP+TF+CLE N + K+VTRFVLPIGATINMDGTALYEAVA+IFIAQ+N + L GQI ++S
Sbjct: 54 GVVFGMLLRYMMVTDLSALTMVSFPGEVLMRMLKMLILPLIISSLITGLAGLDARSSGRMGSRAMVYYMSTTVIAAVLGVILVLGIHPGNPKLRGRTASTATK-NQEVSSLDAFLDLIRNLFPENLVQACIQQVQTVVKT--------VQVVPSNQSE-AVSVVKKKLEYKWGMNVLGLIGFFITFGICMGRMGERGKIMCDFFNILNEIIMTMVSMIMWYSPVGISSLIAGKIAAIGDLETVARQLGMYMVTVIVGLVIHGGLILPAIFFAITRKSPFAFYSGIFQAWITALGTASSAGTLPVTFRCLEENLKIDKRVTRFVLPIGATINMDGTALYEAVAAIFIAQMNDINLDSGQIVTVS 406 HSP 2 Score: 83.5741 bits (205), Expect = 8.718e-94 Identity = 38/74 (51.35%), Postives = 58/74 (78.38%), Query Frame = 2
Query: 1280 ATFAAIGASCVPSSGLVTVIPALASVGLPISDITLILTVDWFLDRVRTTINVLGDSLGSGIIESLLENDKIEID 1501
AT A++GA+ +PS+GLVT++ L +VGLP DI+L++ VDW LDR+RT+INV+GDS G+GI+ L + + ++D
Sbjct: 409 ATLASVGAASIPSAGLVTMLLILTAVGLPTQDISLLIAVDWLLDRMRTSINVVGDSFGAGIVYHLSKGELADLD 482
BLAST of slc1a-4 vs. Planmine SMEST
Match: SMESG000064122.1 (SMESG000064122.1) HSP 1 Score: 737.643 bits (1903), Expect = 0.000e+0 Identity = 412/413 (99.76%), Postives = 412/413 (99.76%), Query Frame = 1
Query: 133 MRKIHLKKFLSNNENILFVLTVFSVFTGLLAGFFIKSTFIVNEYQIYLISFPGEXXXXXXXXXXXXXXXXXXXXXXXXXETKSSGKIGLYTVLYYGITTSISLIMGMVLVVTIHPGNPKIKNLQPLENTGPTSNIGALESIFDLIRNIFPPNLIEGCFRQVATNYAIEKENIYKNFTEFPRNISKLTITMVESTNILGLVFFSITFGLILGQLGNKGKKMFQFFEVLNQVIMTMVTYIMWYFPXXXXXXXXXXXXXXXNLESAASSLGLYIMTVLLGLFIHGGIVLPLMYFIVCKKNPYWFFRALPQAWLASFGTASSTATLPITFKCLESNKLVSKKVTRFVLPIGATINMDGTALYEAVASIFIAQINGMVLSFGQIFSMSYICSNWSLLCTKFRIGNCNSGTGICRSSHQ 1371
MRKIHLKKFLSNNENILFVLTVFSVFTGLLAGFFIKSTFIVNEYQIYLISFPGEMLMNMLKMLILPLLTSSLITGLSVLETKSSGKIGLYTV YYGITTSISLIMGMVLVVTIHPGNPKIKNLQPLENTGPTSNIGALESIFDLIRNIFPPNLIEGCFRQVATNYAIEKENIYKNFTEFPRNISKLTITMVESTNILGLVFFSITFGLILGQLGNKGKKMFQFFEVLNQVIMTMVTYIMWYFPIGIFFLIIGKILEIKNLESAASSLGLYIMTVLLGLFIHGGIVLPLMYFIVCKKNPYWFFRALPQAWLASFGTASSTATLPITFKCLESNKLVSKKVTRFVLPIGATINMDGTALYEAVASIFIAQINGMVLSFGQIFSMSYICSNWSLLCTKFRIGNCNSGTGICRSSHQ
Sbjct: 1 MRKIHLKKFLSNNENILFVLTVFSVFTGLLAGFFIKSTFIVNEYQIYLISFPGEMLMNMLKMLILPLLTSSLITGLSVLETKSSGKIGLYTVFYYGITTSISLIMGMVLVVTIHPGNPKIKNLQPLENTGPTSNIGALESIFDLIRNIFPPNLIEGCFRQVATNYAIEKENIYKNFTEFPRNISKLTITMVESTNILGLVFFSITFGLILGQLGNKGKKMFQFFEVLNQVIMTMVTYIMWYFPIGIFFLIIGKILEIKNLESAASSLGLYIMTVLLGLFIHGGIVLPLMYFIVCKKNPYWFFRALPQAWLASFGTASSTATLPITFKCLESNKLVSKKVTRFVLPIGATINMDGTALYEAVASIFIAQINGMVLSFGQIFSMSYICSNWSLLCTKFRIGNCNSGTGICRSSHQ 413
BLAST of slc1a-4 vs. Planmine SMEST
Match: SMESG000064126.1 (SMESG000064126.1) HSP 1 Score: 381.719 bits (979), Expect = 6.754e-128 Identity = 232/380 (61.05%), Postives = 293/380 (77.11%), Query Frame = 1
Query: 145 HLKKFLSNNENILFVLTVFSVFTGLLAGFFIKSTFIVNEYQIYLISFPGEXXXXXXXXXXXXXXXXXXXXXXXXXETKSSGKIGLYTVLYYGITTSISLIMGMVLVVTIHPGNPKIK-NLQPLENTGPTSNIGALESIFDLIRNIFPPNLIEGCFRQVATNYAIEKENIYKNFTEFPRNISKLTITMVESTNILGLVFFSITFGLILGQLGNKGKKMFQFFEVLNQVIMTMVTYIMWYFPXXXXXXXXXXXXXXXNLESAASSLGLYIMTVLLGLFIHGGIVLPLMYFIVCKKNPYWFFRALPQAWLASFGTASSTATLPITFKCLESNKLVSKKVTRFVLPIGATINMDGTALYEAVASIFIAQINGMVLSFGQIFSMS 1281
L KF N +N+L LT+ SV GL G +K +++ Q+YLI FPGEMLMNMLKMLI+PL+ SSLITGLS L+ KSSGK+GLY ++YY +TT +++I+G++LVV IHPGNP IK +L P T T + L++ DLIRN+ P NLIE CFRQ TNY + E+ Y+N T+ N++K+ I ESTN+LGLV FSI FGLILGQ+G + + MF+FF VLN+V+M +V IMWY PIGIFFLI+GKILEIK+L + ASSLG+Y++TVLLGL IHG I L L++F+ +KNP+ +F + QAW+ + GTASS+ATLPITFKCLE N V K+VTRFVLPIGATINMDGTALYEAVASIFIAQING+ LSFGQIF++S
Sbjct: 10 KLLKFFKNKDNVLVALTIASVVLGLAMGLLLKFVATISDRQVYLIGFPGEMLMNMLKMLIIPLIVSSLITGLSGLDAKSSGKMGLYAIVYYVVTTLMAVILGIILVVAIHPGNPNIKKSLGPGSMTKKT-DTDTLDAFLDLIRNLLPVNLIEACFRQSQTNYVTKLEHFYENGTKVFINVTKMVINHQESTNVLGLVSFSIAFGLILGQMGKEARIMFEFFGVLNEVVMKLVKLIMWYSPIGIFFLIVGKILEIKDLANTASSLGMYMVTVLLGLTIHGCITLNLIFFVFTRKNPFVYFHGMLQAWVTALGTASSSATLPITFKCLEENNGVDKRVTRFVLPIGATINMDGTALYEAVASIFIAQINGIYLSFGQIFTIS 388 HSP 2 Score: 95.9005 bits (237), Expect = 5.913e-21 Identity = 48/73 (65.75%), Postives = 59/73 (80.82%), Query Frame = 2
Query: 1280 ATFAAIGASCVPSSGLVTVIPALASVGLPISDITLILTVDWFLDRVRTTINVLGDSLGSGIIESLLENDKIEI 1498
AT AAIGA+ VPS+GLVT+I L SVGLPI+DITLIL VDW LDRVRT+INVLGD+ G+GI++ L + E+
Sbjct: 391 ATLAAIGAASVPSAGLVTMILVLTSVGLPINDITLILAVDWLLDRVRTSINVLGDAFGAGIVDHLCKKQLEEL 463
BLAST of slc1a-4 vs. Planmine SMEST
Match: SMESG000022787.1 (SMESG000022787.1) HSP 1 Score: 314.309 bits (804), Expect = 7.211e-106 Identity = 197/394 (50.00%), Postives = 270/394 (68.53%), Query Frame = 1
Query: 145 HLKKFLSNNENILFVLTVFSVFTGLLAGFFIKSTFIVNEYQIYLISFPGEXXXXXXXXXXXXXXXXXXXXXXXXXETKSSGKIGLYTVLYYGITTSISLIMGMVLVVTIHPGNPKIKNLQPLENTGPTSNIGALESIFDLIRNIFPPNLIEGCFRQVATNYAIEK----ENIYKNFTEFPRNISKLTIT-----------MVESTNILGLVFFSITFGLILGQLGNKGKKMFQFFEVLNQVIMTMVTYIMWYFPXXXXXXXXXXXXXXXNLESAASSLGLYIMTVLLGLFIHGGIVLPLMYFIVCKKNPYWFFRALPQAWLASFGTASSTATLPITFKCLESNKLVSKKVTRFVLPIGATINMDGTALYEAVASIFIAQINGMVLSFGQIFSMS 1281
+K N +NIL LTV SV G+ G +K T ++Y + LISFPGE+LMNMLKMLI+PL+ SSLI+GL+ L+ KSSG+IG + ++YY TT +++++G++LVV IHPGN IK Q + T L+S DL+RNIFPPN+I+ +Q+++ Y + + + K+ + LT + +STN+LG+V FS+ FGL+L Q+G K M QFF +LN+V+M MV IMWY PIGIF L+IGK+L+I++LE A++LG+Y++TV+ GLFIH L L+Y ++C+K+P FF+ + QAW+ + GTASS ATLPITF+CLE + K+VTRFVLPIGATINMDGTALYEAVASIFIAQIN L QIF++S
Sbjct: 45 KVKGAFKNADNILVSLTVLSVVLGMGVGLVVKLTLRYDDYAVMLISFPGELLMNMLKMLIIPLIVSSLISGLAGLDPKSSGQIGKWALIYYFSTTMMAVVLGIILVVLIHPGNADIKK-QLGQGTNKRRAPSTLDSFLDLLRNIFPPNIIQAAMQQISSKYVNKTKAVTDRMLKDMLSQNKTTEGLTTNSTITYEVTATELTDSTNVLGIVAFSMWFGLVLSQMGEKALIMVQFFALLNEVVMKMVKVIMWYSPIGIFSLVIGKVLQIESLEETAAALGMYMLTVITGLFIHACFTLTLIYVVICRKSPIGFFKGIFQAWITALGTASSAATLPITFRCLEEKIGIDKRVTRFVLPIGATINMDGTALYEAVASIFIAQINARKLEPIQIFTVS 437 HSP 2 Score: 90.1225 bits (222), Expect = 7.211e-106 Identity = 45/74 (60.81%), Postives = 56/74 (75.68%), Query Frame = 2
Query: 1280 ATFAAIGASCVPSSGLVTVIPALASVGLPISDITLILTVDWFLDRVRTTINVLGDSLGSGIIESLLENDKIEID 1501
AT AAIGA+ VPS+GLVT+I L SVGLP DI+LILTVDW LDR+RT+INVLGD+ G+ ++ L + E D
Sbjct: 440 ATLAAIGAASVPSAGLVTMIMVLTSVGLPTDDISLILTVDWLLDRLRTSINVLGDAYGAAVVHHLCKKTLDEQD 513
BLAST of slc1a-4 vs. Planmine SMEST
Match: SMESG000064127.1 (SMESG000064127.1) HSP 1 Score: 281.567 bits (719), Expect = 3.311e-95 Identity = 155/292 (53.08%), Postives = 208/292 (71.23%), Query Frame = 1
Query: 412 YYGITTSISLIMGMVLVVTIHPGNPKIKNLQPLENTGPTSNI--GALESIFDLIRNIFPPNLIEGCFRQVATNYAIEKENIYKNFTEFPRNISKLTITMVESTNILGLVFFSITFGLILGQLGNKGKKMFQFFEVLNQVIMTMVTYIMWYFPXXXXXXXXXXXXXXXNLESAASSLGLYIMTVLLGLFIHGGIVLPLMYFIVCKKNPYWFFRALPQAWLASFGTASSTATLPITFKCLESNKLVSKKVTRFVLPIGATINMDGTALYEAVASIFIAQINGMVLSFGQIFSMS 1281
YY TT +++I+G++LVV+IHPG+P +K+ LE + P I L++ DLIRNIFP NLI CFRQ +T Y E E I N T NI+ + ++TNILGL+ FSI FGL++G +G + + + F +LN IM +V IMWY P GI FLI+GKI+EI++L + SLG Y++TVLLGL IH GIVL L+YFI+ +KNP +FR + QA + + GT+SS+ATLP+T KC+E + K+++R VLPIGATINMDGTALYEAVASIFIAQIN + L+FGQI ++S
Sbjct: 3 YYLFTTLMAVIIGIILVVSIHPGDPTVKD--NLEPSKPGRKIPPKTLDAFLDLIRNIFPVNLISSCFRQASTFYVSEVEKILLNGTLKDVNITNIRHGYQDATNILGLLSFSIVFGLVIGNIGKEADVLIKIFHILNIAIMKIVNMIMWYSPFGIMFLIMGKIIEIRDLRTTVQSLGWYMLTVLLGLLIHAGIVLNLLYFIIVRKNPALYFRGMLQAVITALGTSSSSATLPVTIKCVEEINQIDKRISRLVLPIGATINMDGTALYEAVASIFIAQINAIPLNFGQILTIS 292 HSP 2 Score: 87.0409 bits (214), Expect = 3.311e-95 Identity = 41/69 (59.42%), Postives = 55/69 (79.71%), Query Frame = 2
Query: 1280 ATFAAIGASCVPSSGLVTVIPALASVGLPISDITLILTVDWFLDRVRTTINVLGDSLGSGIIESLLEND 1486
AT AA+GA+ +PS GL+T+I L SVGLPI DI+L+++VDW LDR RT +NVLGD+ G+GI+ SL + D
Sbjct: 295 ATLAAVGAASIPSGGLITMIIVLTSVGLPIDDISLLISVDWLLDRFRTAVNVLGDAYGAGIVGSLCQVD 363
BLAST of slc1a-4 vs. Planmine SMEST
Match: SMESG000064127.1 (SMESG000064127.1) HSP 1 Score: 276.559 bits (706), Expect = 1.260e-93 Identity = 151/285 (52.98%), Postives = 204/285 (71.58%), Query Frame = 1
Query: 433 ISLIMGMVLVVTIHPGNPKIKNLQPLENTGPTSNI--GALESIFDLIRNIFPPNLIEGCFRQVATNYAIEKENIYKNFTEFPRNISKLTITMVESTNILGLVFFSITFGLILGQLGNKGKKMFQFFEVLNQVIMTMVTYIMWYFPXXXXXXXXXXXXXXXNLESAASSLGLYIMTVLLGLFIHGGIVLPLMYFIVCKKNPYWFFRALPQAWLASFGTASSTATLPITFKCLESNKLVSKKVTRFVLPIGATINMDGTALYEAVASIFIAQINGMVLSFGQIFSMS 1281
+++I+G++LVV+IHPG+P +K+ LE + P I L++ DLIRNIFP NLI CFRQ +T Y E E I N T NI+ + ++TNILGL+ FSI FGL++G +G + + + F +LN IM +V IMWY P GI FLI+GKI+EI++L + SLG Y++TVLLGL IH GIVL L+YFI+ +KNP +FR + QA + + GT+SS+ATLP+T KC+E + K+++R VLPIGATINMDGTALYEAVASIFIAQIN + L+FGQI ++S
Sbjct: 1 MAVIIGIILVVSIHPGDPTVKD--NLEPSKPGRKIPPKTLDAFLDLIRNIFPVNLISSCFRQASTFYVSEVEKILLNGTLKDVNITNIRHGYQDATNILGLLSFSIVFGLVIGNIGKEADVLIKIFHILNIAIMKIVNMIMWYSPFGIMFLIMGKIIEIRDLRTTVQSLGWYMLTVLLGLLIHAGIVLNLLYFIIVRKNPALYFRGMLQAVITALGTSSSSATLPVTIKCVEEINQIDKRISRLVLPIGATINMDGTALYEAVASIFIAQINAIPLNFGQILTIS 283 HSP 2 Score: 87.0409 bits (214), Expect = 1.260e-93 Identity = 41/69 (59.42%), Postives = 55/69 (79.71%), Query Frame = 2
Query: 1280 ATFAAIGASCVPSSGLVTVIPALASVGLPISDITLILTVDWFLDRVRTTINVLGDSLGSGIIESLLEND 1486
AT AA+GA+ +PS GL+T+I L SVGLPI DI+L+++VDW LDR RT +NVLGD+ G+GI+ SL + D
Sbjct: 286 ATLAAVGAASIPSGGLITMIIVLTSVGLPIDDISLLISVDWLLDRFRTAVNVLGDAYGAGIVGSLCQVD 354 The following BLAST results are available for this feature:
BLAST of slc1a-4 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of slc1a-4 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of slc1a-4 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of slc1a-4 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of slc1a-4 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of slc1a-4 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of slc1a-4 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of slc1a-4 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of slc1a-4 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of slc1a-4 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of slc1a-4 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of slc1a-4 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of slc1a-4 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of slc1a-4 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Cross References
External references for this transcript
Sequences
The following sequences are available for this feature:
transcript sequence >SMED30008388 ID=SMED30008388|Name=slc1a-4|organism=Schmidtea mediterranea sexual|type=transcript|length=1536bpback to top protein sequence of SMED30008388-orf-1 >SMED30008388-orf-1 ID=SMED30008388-orf-1|Name=SMED30008388-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=414bp MRKIHLKKFLSNNENILFVLTVFSVFTGLLAGFFIKSTFIVNEYQIYLISback to top Aliases
The feature 'slc1a-4' has the following synonyms
Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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