Homeobox protein Nkx-3.2

Overview
NameHomeobox protein Nkx-3.2
Smed IDSMED30008363
Length (bp)843
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Homeobox protein Nkx-3.2 (SMED30008363) t-SNE clustered cells

Violin plots show distribution of expression levels for Homeobox protein Nkx-3.2 (SMED30008363) in cells (dots) of each of the 12 neoblast clusters.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30008363

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 3

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
muscle cellSMED30008363SMESG000027004.1 dd_Smed_v4_30581_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
pharynxSMED30008363SMESG000027004.1 Contig54835newmark_estsPMID:27612384
Roberts-Galbraith et al., 2016		whole organism asexual adult colorimetric in situ hybridization evidence
pharynxSMED30008363SMESG000027004.1 Contig54835uc_Smed_v2PMID:27612384
Roberts-Galbraith et al., 2016		whole organism asexual adult colorimetric in situ hybridization evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Homeobox protein Nkx-3.2 vs. Ensembl Human
Match: NKX3-2 (NK3 homeobox 2 [Source:HGNC Symbol;Acc:HGNC:951])

HSP 1 Score: 112.849 bits (281), Expect = 1.265e-28
Identity = 52/78 (66.67%), Postives = 63/78 (80.77%), Query Frame = 2 
Query:  317 KKKRSRAAFSHNQVYELERRFSHQTYLSGPERTELARSLKLTENQVKIWFQNRRYKTKKRRQQIESEIDTKNPQNFEI 550
            +KKRSRAAFSH QV+ELERRF+HQ YLSGPER +LA SLKLTE QVKIWFQNRRYKTK+R  Q+ +++    P   ++
Sbjct:  205 RKKRSRAAFSHAQVFELERRFNHQRYLSGPERADLAASLKLTETQVKIWFQNRRYKTKRR--QMAADLLASAPAAKKV 280
[Close]
BLAST of Homeobox protein Nkx-3.2 vs. Ensembl Human
Match: NKX3-1 (NK3 homeobox 1 [Source:HGNC Symbol;Acc:HGNC:7838])

HSP 1 Score: 104.375 bits (259), Expect = 4.394e-27
Identity = 50/72 (69.44%), Postives = 59/72 (81.94%), Query Frame = 2 
Query:  305 SERMKKKRSRAAFSHNQVYELERRFSHQTYLSGPERTELARSLKLTENQVKIWFQNRRYKTKKRRQQIESEI 520
            + +  +KRSRAAFSH QV ELER+FSHQ YLS PER  LA++LKLTE QVKIWFQNRRYKTK  R+Q+ SE+
Sbjct:   44 TPKQPQKRSRAAFSHTQVIELERKFSHQKYLSAPERAHLAKNLKLTETQVKIWFQNRRYKTK--RKQLSSEL 113
[Close]
BLAST of Homeobox protein Nkx-3.2 vs. Ensembl Human
Match: NKX3-1 (NK3 homeobox 1 [Source:HGNC Symbol;Acc:HGNC:7838])

HSP 1 Score: 105.145 bits (261), Expect = 1.504e-26
Identity = 50/72 (69.44%), Postives = 59/72 (81.94%), Query Frame = 2 
Query:  305 SERMKKKRSRAAFSHNQVYELERRFSHQTYLSGPERTELARSLKLTENQVKIWFQNRRYKTKKRRQQIESEI 520
            + +  +KRSRAAFSH QV ELER+FSHQ YLS PER  LA++LKLTE QVKIWFQNRRYKTK  R+Q+ SE+
Sbjct:  119 TPKQPQKRSRAAFSHTQVIELERKFSHQKYLSAPERAHLAKNLKLTETQVKIWFQNRRYKTK--RKQLSSEL 188
[Close]
BLAST of Homeobox protein Nkx-3.2 vs. Ensembl Human
Match: NKX2-3 (NK2 homeobox 3 [Source:HGNC Symbol;Acc:HGNC:7836])

HSP 1 Score: 90.8929 bits (224), Expect = 9.974e-21
Identity = 46/80 (57.50%), Postives = 53/80 (66.25%), Query Frame = 2 
Query:  296 ANISERMK---KKRSRAAFSHNQVYELERRFSHQTYLSGPERTELARSLKLTENQVKIWFQNRRYKTKKRRQQIESEIDT 526
            A  SER K   +++ R  FS  QV+ELERRF  Q YLS PER  LA SLKLT  QVKIWFQNRRYK K++RQ    E+  
Sbjct:  137 AEESERPKPRSRRKPRVLFSQAQVFELERRFKQQRYLSAPEREHLASSLKLTSTQVKIWFQNRRYKCKRQRQDKSLELGA 216
[Close]
BLAST of Homeobox protein Nkx-3.2 vs. Ensembl Human
Match: NKX2-3 (NK2 homeobox 3 [Source:HGNC Symbol;Acc:HGNC:7836])

HSP 1 Score: 91.6633 bits (226), Expect = 1.095e-20
Identity = 46/83 (55.42%), Postives = 54/83 (65.06%), Query Frame = 2 
Query:  287 IQPANISERMK---KKRSRAAFSHNQVYELERRFSHQTYLSGPERTELARSLKLTENQVKIWFQNRRYKTKKRRQQIESEIDT 526
             + A  SER K   +++ R  FS  QV+ELERRF  Q YLS PER  LA SLKLT  QVKIWFQNRRYK K++RQ    E+  
Sbjct:  134 CKAAEESERPKPRSRRKPRVLFSQAQVFELERRFKQQRYLSAPEREHLASSLKLTSTQVKIWFQNRRYKCKRQRQDKSLELGA 216
[Close]
BLAST of Homeobox protein Nkx-3.2 vs. Ensembl Celegans
Match: ceh-9 (Homeobox protein ceh-9 [Source:UniProtKB/Swiss-Prot;Acc:P56407])

HSP 1 Score: 83.1889 bits (204), Expect = 1.417e-19
Identity = 53/153 (34.64%), Postives = 84/153 (54.90%), Query Frame = 2 
Query:   98 FYFVVDKFKMMRKSTFLIENLLSETTYENDDISENIDSDVESYFSNDSDLEVSKSSMIVDHHKIQPANISERMKKKRSRAAFSHNQVYELERRFSHQTYLSGPERTELARSLKLTENQVKIWFQNRRYKTKKRRQQIESEIDTKNPQNFEIPN 556
            F  +    K  R+++ LI+++L   T         ++ +++ +    S L+ +K S         P    ++ K+K++R  FS  QV+ELE++F  + YLS  +R+ELA+ L +TE QVKIWFQNRR K KK    IESE      ++ EIP+
Sbjct:   14 FALLTSDVKPQRRTSHLIKDILDLPT---------VNGEIDEFGRCKSSLDQAKES---------PIEKCQKTKRKKARTTFSGKQVFELEKQFEAKKYLSSSDRSELAKRLDVTETQVKIWFQNRRTKWKK----IESE----KERSGEIPD 140
[Close]
BLAST of Homeobox protein Nkx-3.2 vs. Ensembl Celegans
Match: cog-1 (COG-1B [Source:UniProtKB/TrEMBL;Acc:G5EGF2])

HSP 1 Score: 83.9593 bits (206), Expect = 6.315e-19
Identity = 45/120 (37.50%), Postives = 73/120 (60.83%), Query Frame = 2 
Query:  143 FLIENLLSETTYENDDISENIDSDVESY--FSNDSDLEVSKSSMIVDHHKIQPANISERMKKKRSRAAFSHNQVYELERRFSHQTYLSGPERTELARSLKLTENQVKIWFQNRRYKTKKR 496
            FL+++ L+  +  N    EN+   + S+   +N      S S M    H +Q +  S  M+KK+SR  F+ +Q+Y+LER+F    YL+G +R +LA+ L ++E+QVK+WFQNRR K +K+
Sbjct:  108 FLLQSQLNSQSMMNRVTQENVSRALTSFNLLNNLPGALPSLSPMGRLQHSMQLSPNSLNMQKKQSRPTFTGHQIYQLERKFEQTKYLAGADRAQLAQELNMSESQVKVWFQNRRTKWRKK 227
[Close]
BLAST of Homeobox protein Nkx-3.2 vs. Ensembl Celegans
Match: ceh-22 (Homeobox protein ceh-22 [Source:UniProtKB/Swiss-Prot;Acc:P41936])

HSP 1 Score: 80.8777 bits (198), Expect = 5.315e-18
Identity = 42/86 (48.84%), Postives = 51/86 (59.30%), Query Frame = 2 
Query:  341 FSHNQVYELERRFSHQTYLSGPERTELARSLKLTENQVKIWFQNRRYKTKKRR--QQIESEIDTKNPQNFE----IPNFPSRDLSI 580
            F+  Q YELERRF  Q YLS PER  LA  ++LT  QVKIWFQN RYKTKK    + I + + T  P  F       +FP+R + I
Sbjct:   65 FTKAQTYELERRFRSQKYLSAPEREALAMQIRLTPTQVKIWFQNHRYKTKKSHTDKPINAALLTTMPNAFSSQSTAASFPTRAMPI 150
[Close]
BLAST of Homeobox protein Nkx-3.2 vs. Ensembl Celegans
Match: ceh-22 (Homeobox protein ceh-22 [Source:UniProtKB/Swiss-Prot;Acc:P41936])

HSP 1 Score: 81.6481 bits (200), Expect = 5.692e-18
Identity = 42/86 (48.84%), Postives = 51/86 (59.30%), Query Frame = 2 
Query:  341 FSHNQVYELERRFSHQTYLSGPERTELARSLKLTENQVKIWFQNRRYKTKKRR--QQIESEIDTKNPQNFE----IPNFPSRDLSI 580
            F+  Q YELERRF  Q YLS PER  LA  ++LT  QVKIWFQN RYKTKK    + I + + T  P  F       +FP+R + I
Sbjct:  110 FTKAQTYELERRFRSQKYLSAPEREALAMQIRLTPTQVKIWFQNHRYKTKKSHTDKPINAALLTTMPNAFSSQSTAASFPTRAMPI 195
[Close]
BLAST of Homeobox protein Nkx-3.2 vs. Ensembl Celegans
Match: ceh-22 (Homeobox protein ceh-22 [Source:UniProtKB/Swiss-Prot;Acc:P41936])

HSP 1 Score: 81.2629 bits (199), Expect = 9.161e-18
Identity = 42/86 (48.84%), Postives = 51/86 (59.30%), Query Frame = 2 
Query:  341 FSHNQVYELERRFSHQTYLSGPERTELARSLKLTENQVKIWFQNRRYKTKKRR--QQIESEIDTKNPQNFE----IPNFPSRDLSI 580
            F+  Q YELERRF  Q YLS PER  LA  ++LT  QVKIWFQN RYKTKK    + I + + T  P  F       +FP+R + I
Sbjct:  133 FTKAQTYELERRFRSQKYLSAPEREALAMQIRLTPTQVKIWFQNHRYKTKKSHTDKPINAALLTTMPNAFSSQSTAASFPTRAMPI 218
[Close]
BLAST of Homeobox protein Nkx-3.2 vs. Ensembl Fly
Match: bap (gene:FBgn0004862 transcript:FBtr0084087)

HSP 1 Score: 112.464 bits (280), Expect = 1.908e-28
Identity = 57/104 (54.81%), Postives = 72/104 (69.23%), Query Frame = 2 
Query:  212 DVESYFSNDSDLEVSKSSMIVDHHKIQPANISERMKKKRSRAAFSHNQVYELERRFSHQTYLSGPERTELARSLKLTENQVKIWFQNRRYKTKKRR-QQIESEI 520
            D+    SNDSD +                + S   +KKRSRAAFSH QV+ELERRF+ Q YLSGPER+E+A+SL+LTE QVKIWFQNRRYKTK+++ QQ E+ +
Sbjct:  139 DMRRCTSNDSDCDSPPPLSSSPSESPLSHDGSGLSRKKRSRAAFSHAQVFELERRFAQQRYLSGPERSEMAKSLRLTETQVKIWFQNRRYKTKRKQIQQHEAAL 242
[Close]
BLAST of Homeobox protein Nkx-3.2 vs. Ensembl Fly
Match: scro (gene:FBgn0028993 transcript:FBtr0339923)

HSP 1 Score: 80.1073 bits (196), Expect = 4.519e-17
Identity = 39/75 (52.00%), Postives = 47/75 (62.67%), Query Frame = 2 
Query:  317 KKKRSRAAFSHNQVYELERRFSHQTYLSGPERTELARSLKLTENQVKIWFQNRRYKTKKRRQQIESEIDTKNPQN 541
            ++++ R  F+  QVYELERRF  Q YLS PER  LA  + LT  QVKIWFQN RYK K  RQ  E  +  +N  N
Sbjct:   91 QRRKRRVLFTQAQVYELERRFKQQRYLSAPEREHLASLIHLTPTQVKIWFQNHRYKCK--RQAKEKAMAEQNQHN 163
[Close]
BLAST of Homeobox protein Nkx-3.2 vs. Ensembl Fly
Match: vnd (gene:FBgn0261930 transcript:FBtr0070110)

HSP 1 Score: 81.2629 bits (199), Expect = 5.706e-17
Identity = 39/68 (57.35%), Postives = 47/68 (69.12%), Query Frame = 2 
Query:  296 ANISERM--KKKRSRAAFSHNQVYELERRFSHQTYLSGPERTELARSLKLTENQVKIWFQNRRYKTKK 493
            AN S+ +  KK++ R  F+  Q YELERRF  Q YLS PER  LA  ++LT  QVKIWFQN RYKTK+
Sbjct:  535 ANGSDGLPNKKRKRRVLFTKAQTYELERRFRQQRYLSAPEREHLASLIRLTPTQVKIWFQNHRYKTKR 602
[Close]
BLAST of Homeobox protein Nkx-3.2 vs. Ensembl Fly
Match: vnd (gene:FBgn0261930 transcript:FBtr0110929)

HSP 1 Score: 81.2629 bits (199), Expect = 5.787e-17
Identity = 39/72 (54.17%), Postives = 49/72 (68.06%), Query Frame = 2 
Query:  296 ANISERM--KKKRSRAAFSHNQVYELERRFSHQTYLSGPERTELARSLKLTENQVKIWFQNRRYKTKKRRQQ 505
            AN S+ +  KK++ R  F+  Q YELERRF  Q YLS PER  LA  ++LT  QVKIWFQN RYKTK+ + +
Sbjct:  389 ANGSDGLPNKKRKRRVLFTKAQTYELERRFRQQRYLSAPEREHLASLIRLTPTQVKIWFQNHRYKTKRAQNE 460
[Close]
BLAST of Homeobox protein Nkx-3.2 vs. Ensembl Fly
Match: scro (gene:FBgn0028993 transcript:FBtr0113751)

HSP 1 Score: 80.1073 bits (196), Expect = 1.139e-16
Identity = 39/75 (52.00%), Postives = 47/75 (62.67%), Query Frame = 2 
Query:  317 KKKRSRAAFSHNQVYELERRFSHQTYLSGPERTELARSLKLTENQVKIWFQNRRYKTKKRRQQIESEIDTKNPQN 541
            ++++ R  F+  QVYELERRF  Q YLS PER  LA  + LT  QVKIWFQN RYK K  RQ  E  +  +N  N
Sbjct:  252 QRRKRRVLFTQAQVYELERRFKQQRYLSAPEREHLASLIHLTPTQVKIWFQNHRYKCK--RQAKEKAMAEQNQHN 324
[Close]
BLAST of Homeobox protein Nkx-3.2 vs. Ensembl Zebrafish
Match: nkx3-2 (NK3 homeobox 2 [Source:ZFIN;Acc:ZDB-GENE-030127-1])

HSP 1 Score: 112.079 bits (279), Expect = 3.255e-29
Identity = 50/63 (79.37%), Postives = 57/63 (90.48%), Query Frame = 2 
Query:  311 RMKKKRSRAAFSHNQVYELERRFSHQTYLSGPERTELARSLKLTENQVKIWFQNRRYKTKKRR 499
            + +KKRSRAAFSH QV+ELERRF+HQ YLSGPER +LA SLKLTE QVKIWFQNRRYKTK+R+
Sbjct:  117 KQRKKRSRAAFSHAQVFELERRFNHQRYLSGPERADLAASLKLTETQVKIWFQNRRYKTKRRQ 179
[Close]
BLAST of Homeobox protein Nkx-3.2 vs. Ensembl Zebrafish
Match: nkx3.3 (NK3 homeobox 3 [Source:ZFIN;Acc:ZDB-GENE-050306-27])

HSP 1 Score: 104.76 bits (260), Expect = 1.501e-27
Identity = 49/59 (83.05%), Postives = 53/59 (89.83%), Query Frame = 2 
Query:  320 KKRSRAAFSHNQVYELERRFSHQTYLSGPERTELARSLKLTENQVKIWFQNRRYKTKKR 496
            KKRSRAAFSH QVYELERRF+ Q YLSGPER +LA +LKLTE QVKIWFQNRRYKTK+R
Sbjct:   20 KKRSRAAFSHAQVYELERRFNLQRYLSGPERADLAGALKLTETQVKIWFQNRRYKTKRR 78
[Close]
BLAST of Homeobox protein Nkx-3.2 vs. Ensembl Zebrafish
Match: nkx3.3 (NK3 homeobox 3 [Source:ZFIN;Acc:ZDB-GENE-050306-27])

HSP 1 Score: 104.76 bits (260), Expect = 1.501e-27
Identity = 49/59 (83.05%), Postives = 53/59 (89.83%), Query Frame = 2 
Query:  320 KKRSRAAFSHNQVYELERRFSHQTYLSGPERTELARSLKLTENQVKIWFQNRRYKTKKR 496
            KKRSRAAFSH QVYELERRF+ Q YLSGPER +LA +LKLTE QVKIWFQNRRYKTK+R
Sbjct:   20 KKRSRAAFSHAQVYELERRFNLQRYLSGPERADLAGALKLTETQVKIWFQNRRYKTKRR 78
[Close]
BLAST of Homeobox protein Nkx-3.2 vs. Ensembl Zebrafish
Match: nkx3.3 (NK3 homeobox 3 [Source:ZFIN;Acc:ZDB-GENE-050306-27])

HSP 1 Score: 105.531 bits (262), Expect = 7.425e-27
Identity = 59/121 (48.76%), Postives = 76/121 (62.81%), Query Frame = 2 
Query:  137 STFLIENLLSETTYENDDISENIDSDVESYFSNDSDLEVSKSSMIVDHHKIQPANISERMKKKRSRAAFSHNQVYELERRFSHQTYLSGPERTELARSLKLTENQVKIWFQNRRYKTKKRR 499
            S  L+   LS   +  ++ S   D+ +E    ++ D +  +S    D +         +  KKRSRAAFSH QVYELERRF+ Q YLSGPER +LA +LKLTE QVKIWFQNRRYKTK+R+
Sbjct:   58 SCVLVLESLSSDQHSCEEESTGEDNSLERRHDHEMDQQKPQSCSFEDSNP--------KSSKKRSRAAFSHAQVYELERRFNLQRYLSGPERADLAGALKLTETQVKIWFQNRRYKTKRRQ 170
[Close]
BLAST of Homeobox protein Nkx-3.2 vs. Ensembl Zebrafish
Match: nkx3-1 (NK3 homeobox 1 [Source:ZFIN;Acc:ZDB-GENE-081104-238])

HSP 1 Score: 104.76 bits (260), Expect = 8.882e-27
Identity = 60/130 (46.15%), Postives = 81/130 (62.31%), Query Frame = 2 
Query:  137 STFLIENLLSETTYENDDISENIDSDVESYFSNDSDLEVSKSSMIVDHHKIQPANISERM-KKKRSRAAFSHNQVYELERRFSHQTYLSGPERTELARSLKLTENQVKIWFQNRRYKTKKRRQQIESEID 523
            ++F IE++LS    + D+ S N +SD +   S D   + + +    +   +    ++    KKKRSRAAF+H QV ELE++FS Q YLS PERT LA +L LTE QVKIWFQNRRYKTK+R+   E   D
Sbjct:   38 TSFFIEDILSLKEDKKDEDSCNAESDRDD--STDRQTDSADTCRTSEGKTVSSTEMTGGGGKKKRSRAAFTHLQVLELEKKFSRQRYLSAPERTHLASALHLTETQVKIWFQNRRYKTKRRQLTTEHSKD 165
[Close]
BLAST of Homeobox protein Nkx-3.2 vs. Ensembl Xenopus
Match: ENSXETT00000030786.1 (NK3 homeobox 2 [Source:NCBI gene;Acc:100497965])

HSP 1 Score: 111.694 bits (278), Expect = 2.853e-28
Identity = 50/62 (80.65%), Postives = 56/62 (90.32%), Query Frame = 2 
Query:  311 RMKKKRSRAAFSHNQVYELERRFSHQTYLSGPERTELARSLKLTENQVKIWFQNRRYKTKKR 496
            + +KKRSRAAFSH QV+ELERRF+HQ YLSGPER +LA SLKLTE QVKIWFQNRRYKTK+R
Sbjct:  199 KQRKKRSRAAFSHAQVFELERRFNHQRYLSGPERADLAASLKLTETQVKIWFQNRRYKTKRR 260
[Close]
BLAST of Homeobox protein Nkx-3.2 vs. Ensembl Xenopus
Match: ENSXETT00000032017.1 (NK3 homeobox 3 [Source:NCBI gene;Acc:100485176])

HSP 1 Score: 108.612 bits (270), Expect = 5.451e-28
Identity = 50/64 (78.12%), Postives = 55/64 (85.94%), Query Frame = 2 
Query:  305 SERMKKKRSRAAFSHNQVYELERRFSHQTYLSGPERTELARSLKLTENQVKIWFQNRRYKTKKR 496
            S +  KKRSRAAFSH QVYELERRFS Q YLSGPER +LA +LKLTE QVKIWFQNRRYKTK++
Sbjct:   95 SPKSSKKRSRAAFSHAQVYELERRFSLQRYLSGPERADLAAALKLTETQVKIWFQNRRYKTKRK 158
[Close]
BLAST of Homeobox protein Nkx-3.2 vs. Ensembl Xenopus
Match: ENSXETT00000017291.1 (NK3 homeobox 3 [Source:NCBI gene;Acc:100485176])

HSP 1 Score: 108.612 bits (270), Expect = 8.074e-28
Identity = 50/64 (78.12%), Postives = 55/64 (85.94%), Query Frame = 2 
Query:  305 SERMKKKRSRAAFSHNQVYELERRFSHQTYLSGPERTELARSLKLTENQVKIWFQNRRYKTKKR 496
            S +  KKRSRAAFSH QVYELERRFS Q YLSGPER +LA +LKLTE QVKIWFQNRRYKTK++
Sbjct:  112 SPKSSKKRSRAAFSHAQVYELERRFSLQRYLSGPERADLAAALKLTETQVKIWFQNRRYKTKRK 175
[Close]
BLAST of Homeobox protein Nkx-3.2 vs. Ensembl Xenopus
Match: ENSXETT00000050503.1 (NK3 homeobox 1 [Source:NCBI gene;Acc:100038192])

HSP 1 Score: 105.916 bits (263), Expect = 4.390e-27
Identity = 50/79 (63.29%), Postives = 64/79 (81.01%), Query Frame = 2 
Query:  287 IQPANISERMKKKRSRAAFSHNQVYELERRFSHQTYLSGPERTELARSLKLTENQVKIWFQNRRYKTKKRRQQIESEID 523
            I P     ++++KRSRAAFSH+QV ELER+FS Q YLS PER +LA+SLKLTE QVKIWFQNRRYKTK  R+Q+ ++++
Sbjct:   89 ISPVEKKLKLQQKRSRAAFSHSQVIELERKFSSQKYLSAPERAQLAKSLKLTETQVKIWFQNRRYKTK--RKQLATDME 165
[Close]
BLAST of Homeobox protein Nkx-3.2 vs. Ensembl Xenopus
Match: NKX2-3 (NK2 homeobox 3 [Source:NCBI gene;Acc:100486189])

HSP 1 Score: 91.2781 bits (225), Expect = 9.143e-21
Identity = 43/81 (53.09%), Postives = 55/81 (67.90%), Query Frame = 2 
Query:  284 KIQPANISERMKKKRSRAAFSHNQVYELERRFSHQTYLSGPERTELARSLKLTENQVKIWFQNRRYKTKKRRQQIESEIDT 526
            K++  +  ++  +++ R  FS  QV+ELERRF  Q YLS PER  LA SLKLT  QVKIWFQNRRYK K++RQ    E+ T
Sbjct:  134 KLEDPDRPKQRSRRKPRVLFSQAQVFELERRFKQQRYLSAPEREHLANSLKLTSTQVKIWFQNRRYKCKRQRQDKSLEMGT 214
[Close]
BLAST of Homeobox protein Nkx-3.2 vs. Ensembl Mouse
Match: Nkx3-2 (NK3 homeobox 2 [Source:MGI Symbol;Acc:MGI:108015])

HSP 1 Score: 113.62 bits (283), Expect = 5.747e-29
Identity = 52/78 (66.67%), Postives = 63/78 (80.77%), Query Frame = 2 
Query:  317 KKKRSRAAFSHNQVYELERRFSHQTYLSGPERTELARSLKLTENQVKIWFQNRRYKTKKRRQQIESEIDTKNPQNFEI 550
            +KKRSRAAFSH QV+ELERRF+HQ YLSGPER +LA SLKLTE QVKIWFQNRRYKTK+R  Q+ +++    P   ++
Sbjct:  205 RKKRSRAAFSHAQVFELERRFNHQRYLSGPERADLAASLKLTETQVKIWFQNRRYKTKRR--QMAADLLASAPAAKKV 280
[Close]
BLAST of Homeobox protein Nkx-3.2 vs. Ensembl Mouse
Match: Nkx3-1 (NK3 homeobox 1 [Source:MGI Symbol;Acc:MGI:97352])

HSP 1 Score: 103.219 bits (256), Expect = 5.343e-26
Identity = 46/63 (73.02%), Postives = 54/63 (85.71%), Query Frame = 2 
Query:  311 RMKKKRSRAAFSHNQVYELERRFSHQTYLSGPERTELARSLKLTENQVKIWFQNRRYKTKKRR 499
            +  +KRSRAAFSH QV ELER+FSHQ YLS PER  LA++LKLTE QVKIWFQNRRYKTK+++
Sbjct:  122 KQPQKRSRAAFSHTQVIELERKFSHQKYLSAPERAHLAKNLKLTETQVKIWFQNRRYKTKRKQ 184
[Close]
BLAST of Homeobox protein Nkx-3.2 vs. Ensembl Mouse
Match: Nkx2-3 (NK2 homeobox 3 [Source:MGI Symbol;Acc:MGI:97348])

HSP 1 Score: 91.6633 bits (226), Expect = 7.592e-21
Identity = 53/114 (46.49%), Postives = 62/114 (54.39%), Query Frame = 2 
Query:  320 KKRSRAAFSHNQVYELERRFSHQTYLSGPERTELARSLKLTENQVKIWFQNRRYKTKKRRQQIESEIDTKNPQNFEIPNFPSRDLSIKDEMNNHSFNTNGSVNGFGSHCY-YNS 658
            +++ R  FS  QV+ELERRF  Q YLS PER  LA SLKLT  QVKIWFQNRRYK K++RQ    E+ T  P            +         S  T GS  G G+  Y YNS
Sbjct:  145 RRKPRVLFSQAQVFELERRFKQQRYLSAPEREHLASSLKLTSTQVKIWFQNRRYKCKRQRQDKSLELGTHAPPPPPRRVAVPVLVRDGKPCVTPSAQTYGSPYGVGAGAYSYNS 258
[Close]
BLAST of Homeobox protein Nkx-3.2 vs. Ensembl Mouse
Match: Nkx2-9 (NK2 homeobox 9 [Source:MGI Symbol;Acc:MGI:1270158])

HSP 1 Score: 87.8113 bits (216), Expect = 3.836e-20
Identity = 49/102 (48.04%), Postives = 62/102 (60.78%), Query Frame = 2 
Query:  203 IDSDVESYFSND-SDLEVSK--SSMIVDHHKIQPANISERMKKKRSRAAFSHNQVYELERRFSHQTYLSGPERTELARSLKLTENQVKIWFQNRRYKTKKRR 499
            ++S+   Y S+D S LE S   SS +    +  P +  E+ +K+R    FS  Q  ELERRF  Q YLS PER +LAR L+LT  QVKIWFQN RYK K+ R
Sbjct:   41 LESECSHYLSSDESGLETSPADSSQLASLRRESPGSDPEKRRKRR--VLFSKAQTLELERRFRQQRYLSAPEREQLARLLRLTPTQVKIWFQNHRYKLKRGR 140
[Close]
BLAST of Homeobox protein Nkx-3.2 vs. Ensembl Mouse
Match: Nkx2-5 (NK2 homeobox 5 [Source:MGI Symbol;Acc:MGI:97350])

HSP 1 Score: 88.9669 bits (219), Expect = 4.422e-20
Identity = 39/54 (72.22%), Postives = 42/54 (77.78%), Query Frame = 2 
Query:  341 FSHNQVYELERRFSHQTYLSGPERTELARSLKLTENQVKIWFQNRRYKTKKRRQ 502
            FS  QVYELERRF  Q YLS PER +LA  LKLT  QVKIWFQNRRYK K++RQ
Sbjct:  144 FSQAQVYELERRFKQQRYLSAPERDQLASVLKLTSTQVKIWFQNRRYKCKRQRQ 197
[Close]
BLAST of Homeobox protein Nkx-3.2 vs. UniProt/SwissProt
Match: sp|P97503|NKX32_MOUSE (Homeobox protein Nkx-3.2 OS=Mus musculus OX=10090 GN=Nkx3-2 PE=1 SV=2)

HSP 1 Score: 113.62 bits (283), Expect = 4.020e-28
Identity = 52/78 (66.67%), Postives = 63/78 (80.77%), Query Frame = 2 
Query:  317 KKKRSRAAFSHNQVYELERRFSHQTYLSGPERTELARSLKLTENQVKIWFQNRRYKTKKRRQQIESEIDTKNPQNFEI 550
            +KKRSRAAFSH QV+ELERRF+HQ YLSGPER +LA SLKLTE QVKIWFQNRRYKTK+R  Q+ +++    P   ++
Sbjct:  205 RKKRSRAAFSHAQVFELERRFNHQRYLSGPERADLAASLKLTETQVKIWFQNRRYKTKRR--QMAADLLASAPAAKKV 280
[Close]
BLAST of Homeobox protein Nkx-3.2 vs. UniProt/SwissProt
Match: sp|P78367|NKX32_HUMAN (Homeobox protein Nkx-3.2 OS=Homo sapiens OX=9606 GN=NKX3-2 PE=1 SV=2)

HSP 1 Score: 112.849 bits (281), Expect = 6.074e-28
Identity = 52/78 (66.67%), Postives = 63/78 (80.77%), Query Frame = 2 
Query:  317 KKKRSRAAFSHNQVYELERRFSHQTYLSGPERTELARSLKLTENQVKIWFQNRRYKTKKRRQQIESEIDTKNPQNFEI 550
            +KKRSRAAFSH QV+ELERRF+HQ YLSGPER +LA SLKLTE QVKIWFQNRRYKTK+R  Q+ +++    P   ++
Sbjct:  205 RKKRSRAAFSHAQVFELERRFNHQRYLSGPERADLAASLKLTETQVKIWFQNRRYKTKRR--QMAADLLASAPAAKKV 280
[Close]
BLAST of Homeobox protein Nkx-3.2 vs. UniProt/SwissProt
Match: sp|P22809|BAGP_DROME (Homeobox protein bagpipe OS=Drosophila melanogaster OX=7227 GN=bap PE=2 SV=3)

HSP 1 Score: 112.464 bits (280), Expect = 1.912e-27
Identity = 57/104 (54.81%), Postives = 72/104 (69.23%), Query Frame = 2 
Query:  212 DVESYFSNDSDLEVSKSSMIVDHHKIQPANISERMKKKRSRAAFSHNQVYELERRFSHQTYLSGPERTELARSLKLTENQVKIWFQNRRYKTKKRR-QQIESEI 520
            D+    SNDSD +                + S   +KKRSRAAFSH QV+ELERRF+ Q YLSGPER+E+A+SL+LTE QVKIWFQNRRYKTK+++ QQ E+ +
Sbjct:  139 DMRRCTSNDSDCDSPPPLSSSPSESPLSHDGSGLSRKKRSRAAFSHAQVFELERRFAQQRYLSGPERSEMAKSLRLTETQVKIWFQNRRYKTKRKQIQQHEAAL 242
[Close]
BLAST of Homeobox protein Nkx-3.2 vs. UniProt/SwissProt
Match: sp|P70061|NKX32_XENLA (Homeobox protein Nkx-3.2 OS=Xenopus laevis OX=8355 GN=nkx3-2 PE=2 SV=1)

HSP 1 Score: 111.309 bits (277), Expect = 2.531e-27
Identity = 50/62 (80.65%), Postives = 56/62 (90.32%), Query Frame = 2 
Query:  311 RMKKKRSRAAFSHNQVYELERRFSHQTYLSGPERTELARSLKLTENQVKIWFQNRRYKTKKR 496
            + +KKRSRAAFSH QV+ELERRF+HQ YLSGPER +LA SLKLTE QVKIWFQNRRYKTK+R
Sbjct:  199 KQRKKRSRAAFSHAQVFELERRFNHQRYLSGPERADLAASLKLTETQVKIWFQNRRYKTKRR 260
[Close]
BLAST of Homeobox protein Nkx-3.2 vs. UniProt/SwissProt
Match: sp|O93590|ZAX_XENLA (Homeobox protein zampogna OS=Xenopus laevis OX=8355 GN=zax PE=2 SV=1)

HSP 1 Score: 108.612 bits (270), Expect = 2.740e-27
Identity = 58/99 (58.59%), Postives = 66/99 (66.67%), Query Frame = 2 
Query:  200 NIDSDVESYFSNDSDLEVSKSSMIVDHHKIQPANISERMKKKRSRAAFSHNQVYELERRFSHQTYLSGPERTELARSLKLTENQVKIWFQNRRYKTKKR 496
            + DS  E  F  + D E + +    D         S +  KKRSRAAFSH QVYELERRFS Q YLSGPER +LA SLKLTE QVKIWFQNRRYKTK++
Sbjct:   61 DTDSGTED-FHWERDTETANNGAFTDPSSGDRLADSPKSSKKRSRAAFSHAQVYELERRFSLQRYLSGPERADLAASLKLTETQVKIWFQNRRYKTKRK 158
[Close]
BLAST of Homeobox protein Nkx-3.2 vs. TrEMBL
Match: A0A3B3BB18 (NK3 homeobox 3 OS=Oryzias melastigma OX=30732 PE=4 SV=1)

HSP 1 Score: 119.783 bits (299), Expect = 6.956e-29
Identity = 61/122 (50.00%), Postives = 83/122 (68.03%), Query Frame = 2 
Query:  197 ENIDSDVESYFSNDSDLEVSKSSMIVDHHKIQ-------PANISERMK--KKRSRAAFSHNQVYELERRFSHQTYLSGPERTELARSLKLTENQVKIWFQNRRYKTKKRRQQIESEIDTKNP 535
            E ++++V+  FS + D ++   +  V+  ++Q       P +  +R    KKR+RAAFSH QV+ELERRFS Q YLSGPER +LA +LKLTE QVKIWFQNRRYKTK+R  Q+ +E+   NP
Sbjct:   63 EPLETEVKQEFSAERDEQLQSQARAVEEERLQRREACCCPRDDRQRRPGTKKRARAAFSHTQVHELERRFSAQRYLSGPERADLAEALKLTETQVKIWFQNRRYKTKRR--QVAAEVAALNP 182
[Close]
BLAST of Homeobox protein Nkx-3.2 vs. TrEMBL
Match: A0A182P3Z1 (Protein bagpipe OS=Anopheles epiroticus OX=199890 PE=4 SV=1)

HSP 1 Score: 124.02 bits (310), Expect = 1.171e-28
Identity = 64/108 (59.26%), Postives = 79/108 (73.15%), Query Frame = 2 
Query:  212 DVESYFSNDSDLEVSKS-SMIVDHHKIQPANISERM---KKKRSRAAFSHNQVYELERRFSHQTYLSGPERTELARSLKLTENQVKIWFQNRRYKTKKRR-QQIESEI 520
            D+     NDSD + S   S  + HH  QP   SE M   +KKRSRAAFSH QV+ELERRF+ Q YLSGPER+ELA++L+LTE QVKIWFQNRRYKTK+++ QQ E+ +
Sbjct:  206 DMRRMAENDSDCDSSSPYSGTLGHHGGQPTLASEEMPSARKKRSRAAFSHAQVFELERRFAQQRYLSGPERSELAKNLRLTETQVKIWFQNRRYKTKRKQIQQHEAAL 313
[Close]
BLAST of Homeobox protein Nkx-3.2 vs. TrEMBL
Match: H2LU88 (NK3 homeobox 3 OS=Oryzias latipes OX=8090 PE=4 SV=2)

HSP 1 Score: 115.546 bits (288), Expect = 1.769e-28
Identity = 56/94 (59.57%), Postives = 68/94 (72.34%), Query Frame = 2 
Query:  320 KKRSRAAFSHNQVYELERRFSHQTYLSGPERTELARSLKLTENQVKIWFQNRRYKTKKRRQQIESEIDTKNPQNFEIPNFPSRDLSIKDEMNNH 601
            KKRSRAAFSH QV+ELERRFS Q YLSGPER +LA +LKLTE QVKIWFQNRRYKTK+R  Q+ +E+   NP+   +       + ++DE   H
Sbjct:   10 KKRSRAAFSHTQVHELERRFSAQRYLSGPERADLAEALKLTETQVKIWFQNRRYKTKRR--QVAAEVAALNPKTVSV------KVLVRDEEKQH 95
[Close]
BLAST of Homeobox protein Nkx-3.2 vs. TrEMBL
Match: A0A4Z2C4W1 (Homeobox domain-containing protein OS=Takifugu bimaculatus OX=433685 GN=fugu_013540 PE=4 SV=1)

HSP 1 Score: 119.013 bits (297), Expect = 2.582e-28
Identity = 70/130 (53.85%), Postives = 86/130 (66.15%), Query Frame = 2 
Query:  146 LIENLLSETTYENDDISENIDSDVESYFSNDSDLEVSKSSMIVDHHKIQPANISERMKKKRSRAAFSHNQVYELERRFSHQTYLSGPERTELARSLKLTENQVKIWFQNRRYKTKKRRQQIESEIDTKNP 535
            + E  L ET +E+   +EN  SD E   SN +D     SS + D    QP     + +KKRSRAAFSH QV+ELERRF+HQ YLSGPER +LA SLKLTE QVKIWFQNRRYKTK+R  Q+ +++    P
Sbjct:   96 VPEESLQETDHESA-TAENAKSDSEP--SNTTD-----SSTVEDKSPDQP-----KQRKKRSRAAFSHAQVFELERRFNHQRYLSGPERADLAASLKLTETQVKIWFQNRRYKTKRR--QMAADLMASTP 210
[Close]
BLAST of Homeobox protein Nkx-3.2 vs. TrEMBL
Match: A0A5C6MJI3 (Homeobox protein OS=Takifugu flavidus OX=433684 GN=D4764_09G0003450 PE=4 SV=1)

HSP 1 Score: 119.013 bits (297), Expect = 2.582e-28
Identity = 70/130 (53.85%), Postives = 86/130 (66.15%), Query Frame = 2 
Query:  146 LIENLLSETTYENDDISENIDSDVESYFSNDSDLEVSKSSMIVDHHKIQPANISERMKKKRSRAAFSHNQVYELERRFSHQTYLSGPERTELARSLKLTENQVKIWFQNRRYKTKKRRQQIESEIDTKNP 535
            + E  L ET +E+   +EN  SD E   SN +D     SS + D    QP     + +KKRSRAAFSH QV+ELERRF+HQ YLSGPER +LA SLKLTE QVKIWFQNRRYKTK+R  Q+ +++    P
Sbjct:   96 VPEESLQETDHESA-TAENAKSDSEP--SNTTD-----SSTVEDKSPDQP-----KQRKKRSRAAFSHAQVFELERRFNHQRYLSGPERADLAASLKLTETQVKIWFQNRRYKTKRR--QMAADLMASTP 210
[Close]
BLAST of Homeobox protein Nkx-3.2 vs. Ensembl Cavefish
Match: nkx3-2 (homeobox protein Nkx-3.2 [Source:NCBI gene;Acc:103036631])

HSP 1 Score: 114.005 bits (284), Expect = 1.117e-29
Identity = 57/94 (60.64%), Postives = 67/94 (71.28%), Query Frame = 2 
Query:  239 SDLEVSKSSMIVDHHKIQPANISE--------RMKKKRSRAAFSHNQVYELERRFSHQTYLSGPERTELARSLKLTENQVKIWFQNRRYKTKKR 496
            SD E+S S  + D   ++     E        + +KKRSRAAFSH QV+ELERRF+HQ YLSGPER +LA SLKLTE QVKIWFQNRRYKTK+R
Sbjct:  116 SDCELSNS--VCDSSTVEEPGCCEDRTTSDPPKQRKKRSRAAFSHAQVFELERRFNHQRYLSGPERADLAASLKLTETQVKIWFQNRRYKTKRR 207
[Close]
BLAST of Homeobox protein Nkx-3.2 vs. Ensembl Cavefish
Match: nkx3-2 (homeobox protein Nkx-3.2 [Source:NCBI gene;Acc:103036631])

HSP 1 Score: 110.923 bits (276), Expect = 5.207e-29
Identity = 50/62 (80.65%), Postives = 56/62 (90.32%), Query Frame = 2 
Query:  311 RMKKKRSRAAFSHNQVYELERRFSHQTYLSGPERTELARSLKLTENQVKIWFQNRRYKTKKR 496
            + +KKRSRAAFSH QV+ELERRF+HQ YLSGPER +LA SLKLTE QVKIWFQNRRYKTK+R
Sbjct:  112 KQRKKRSRAAFSHAQVFELERRFNHQRYLSGPERADLAASLKLTETQVKIWFQNRRYKTKRR 173
[Close]
BLAST of Homeobox protein Nkx-3.2 vs. Ensembl Cavefish
Match: nkx3.3 (homeobox protein Nkx-3.2-like [Source:NCBI gene;Acc:103035307])

HSP 1 Score: 104.76 bits (260), Expect = 1.693e-26
Identity = 51/67 (76.12%), Postives = 56/67 (83.58%), Query Frame = 2 
Query:  320 KKRSRAAFSHNQVYELERRFSHQTYLSGPERTELARSLKLTENQVKIWFQNRRYKTKKRRQQIESEI 520
            KKRSRAAFSH QV ELERRF  Q YLSGPER +LA +LKLTE QVKIWFQNRRYKTK+R  QI +E+
Sbjct:  123 KKRSRAAFSHAQVCELERRFHVQRYLSGPERADLAGALKLTETQVKIWFQNRRYKTKRR--QIAAEL 187
[Close]
BLAST of Homeobox protein Nkx-3.2 vs. Ensembl Cavefish
Match: nkx3-1 (NK3 homeobox 1 [Source:NCBI gene;Acc:103038181])

HSP 1 Score: 97.8265 bits (242), Expect = 2.084e-24
Identity = 47/67 (70.15%), Postives = 55/67 (82.09%), Query Frame = 2 
Query:  317 KKKRSRAAFSHNQVYELERRFSHQTYLSGPERTELARSLKLTENQVKIWFQNRRYKTKKRRQQIESE 517
            K+KRSRAAF+H QV ELE++FS Q YLS PER  LA SL+LTE QVKIWFQNRRYKTK  R+Q+ +E
Sbjct:   85 KQKRSRAAFTHVQVLELEKKFSRQKYLSAPERAHLATSLRLTETQVKIWFQNRRYKTK--RKQLATE 149
[Close]
BLAST of Homeobox protein Nkx-3.2 vs. Ensembl Cavefish
Match: ENSAMXT00000002203.2 (pep primary_assembly:Astyanax_mexicanus-2.0:9:20913167:20916891:1 gene:ENSAMXG00000002158.2 transcript:ENSAMXT00000002203.2 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 86.2705 bits (212), Expect = 1.835e-20
Identity = 43/75 (57.33%), Postives = 49/75 (65.33%), Query Frame = 2 
Query:  275 DHHKIQPANISERMKKKRSRAAFSHNQVYELERRFSHQTYLSGPERTELARSLKLTENQVKIWFQNRRYKTKKRR 499
            + HK Q  +     KKK+ R  FS  Q YELERRF  Q YLS PER  LAR+L+LT  QVKIWFQN RYK K+ R
Sbjct:    2 ERHKPQSFSTEMEQKKKKRRVLFSKTQTYELERRFRQQRYLSAPEREHLARALRLTPTQVKIWFQNHRYKMKRAR 76
[Close]
BLAST of Homeobox protein Nkx-3.2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000005776.1 (pep scaffold:Pmarinus_7.0:GL477528:542110:542457:1 gene:ENSPMAG00000005236.1 transcript:ENSPMAT00000005776.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 77.7962 bits (190), Expect = 9.365e-19
Identity = 39/61 (63.93%), Postives = 43/61 (70.49%), Query Frame = 2 
Query:  317 KKKRSRAAFSHNQVYELERRFSHQTYLSGPERTELARSLKLTENQVKIWFQNRRYKTKKRR 499
            KK++ R  FS  Q +ELERRF HQ YLS PER  LA  LKLT  QVKIWFQN RYK K+ R
Sbjct:    1 KKRKRRVLFSKAQTFELERRFRHQRYLSAPEREHLASLLKLTPTQVKIWFQNHRYKMKRAR 61
[Close]
BLAST of Homeobox protein Nkx-3.2 vs. Ensembl Sea Lamprey
Match: nkx2.1 (NK2 homeobox 1 [Source:ZFIN;Acc:ZDB-GENE-010404-1])

HSP 1 Score: 78.9518 bits (193), Expect = 8.272e-18
Identity = 35/59 (59.32%), Postives = 41/59 (69.49%), Query Frame = 2 
Query:  320 KKRSRAAFSHNQVYELERRFSHQTYLSGPERTELARSLKLTENQVKIWFQNRRYKTKKR 496
            +++ R  FS  QVYELERRF  Q YLS PER  LA  + LT  QVKIWFQN RYK K++
Sbjct:   40 RRKRRVLFSQAQVYELERRFKQQKYLSAPEREHLASMIHLTPTQVKIWFQNHRYKMKRQ 98
[Close]
BLAST of Homeobox protein Nkx-3.2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001141.1 (pep scaffold:Pmarinus_7.0:GL478075:36995:38394:-1 gene:ENSPMAG00000001023.1 transcript:ENSPMAT00000001141.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 74.3294 bits (181), Expect = 2.291e-17
Identity = 36/59 (61.02%), Postives = 43/59 (72.88%), Query Frame = 2 
Query:  317 KKKRSRAAFSHNQVYELERRFSHQTYLSGPERTELARSLKLTENQVKIWFQNRRYKTKK 493
            K +R R AFS  Q+ ELER FS Q YLS P+R ++A +L LTE QVKIWFQNRR K K+
Sbjct:    2 KCRRPRTAFSSQQLLELERHFSRQRYLSRPQRFQVASALMLTETQVKIWFQNRRMKWKR 60
[Close]
BLAST of Homeobox protein Nkx-3.2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001480.1 (pep scaffold:Pmarinus_7.0:GL487501:66:2428:-1 gene:ENSPMAG00000001338.1 transcript:ENSPMAT00000001480.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 70.0922 bits (170), Expect = 1.297e-15
Identity = 30/57 (52.63%), Postives = 42/57 (73.68%), Query Frame = 2 
Query:  314 MKKKRSRAAFSHNQVYELERRFSHQTYLSGPERTELARSLKLTENQVKIWFQNRRYK 484
            ++++++R  F+ +Q+  LERRF  Q YLS PER +LA +L L+E QVK WFQNRR K
Sbjct:    4 VRRRKARTVFTDSQLSGLERRFVRQRYLSTPERVDLATALGLSETQVKTWFQNRRMK 60
[Close]
BLAST of Homeobox protein Nkx-3.2 vs. Ensembl Sea Lamprey
Match: HMX1 (H6 family homeobox 1 [Source:HGNC Symbol;Acc:HGNC:5017])

HSP 1 Score: 68.9366 bits (167), Expect = 5.084e-15
Identity = 34/58 (58.62%), Postives = 41/58 (70.69%), Query Frame = 2 
Query:  320 KKRSRAAFSHNQVYELERRFSHQTYLSGPERTELARSLKLTENQVKIWFQNRRYKTKK 493
            KK++R  FS +QV++LE  F  + YLS  ER  LA SL LTE QVKIWFQNRR K K+
Sbjct:    1 KKKTRTVFSRSQVFQLESTFDMKRYLSSAERAGLAASLHLTETQVKIWFQNRRNKWKR 58
[Close]
BLAST of Homeobox protein Nkx-3.2 vs. Ensembl Nematostella
Match: NK-3 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S7L1])

HSP 1 Score: 117.472 bits (293), Expect = 1.258e-31
Identity = 66/142 (46.48%), Postives = 85/142 (59.86%), Query Frame = 2 
Query:  311 RMKKKRSRAAFSHNQVYELERRFSHQTYLSGPERTELARSLKLTENQVKIWFQNRRYKTKKRRQQIESEI-----------------DTKNPQNFEIPNFPSRDLSIKDEMNNHSFNTNGSVNGFGSHCYYNSVIDSLLRSS 685
            + ++KRSRAAFSH QV+ELERRFSHQ YLSGPER +LA +LKLTE QVKIWFQNRRYKTK+R  Q+ SEI                 D K  ++  +P  PS  ++           + GS+  +G +C     +D +L SS
Sbjct:  127 KPRRKRSRAAFSHQQVFELERRFSHQKYLSGPERADLAAALKLTETQVKIWFQNRRYKTKRR--QLASEICPPSAAKKVAVRVLVRDDRKQYEDLGLPAVPSYPVTPY-------VPSFGSLGSYGLYC-----LDHMLPSS 254
[Close]
BLAST of Homeobox protein Nkx-3.2 vs. Ensembl Nematostella
Match: EDO33946 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SQP5])

HSP 1 Score: 86.2705 bits (212), Expect = 3.788e-21
Identity = 52/133 (39.10%), Postives = 68/133 (51.13%), Query Frame = 2 
Query:  308 ERMKKKRSRAAFSHNQVYELERRFSHQTYLSGPERTELARSLKLTENQVKIWFQNRRYKTKKRRQQIESEIDTKNPQNFEIPNFPSRDLSIKDEMNNHSFNTNGSVNGFGSH-----CYYNSVIDSLLRSSPY 691
            E  KK++ R  F+  Q YELERRF  Q YLS PER +LAR + LT  QVKIWFQN RYK KK+  +       K P +   P F  R + +   + +       S+N F  H      +Y  V  S + + PY
Sbjct:    3 EPPKKRKRRVLFTKAQTYELERRFRQQRYLSAPEREQLARIINLTPTQVKIWFQNHRYKFKKQNYE-------KGPLSEPPPLFTPRTVPVPVLVRDGQPCHGASMNNFAYHHAADFLHYPPVSTSYMPAHPY 128
[Close]
BLAST of Homeobox protein Nkx-3.2 vs. Ensembl Nematostella
Match: NK-4 (NK-4 homeobox protein; Predicted protein [Source:UniProtKB/TrEMBL;Acc:Q7YZD1])

HSP 1 Score: 86.6557 bits (213), Expect = 6.782e-20
Identity = 42/67 (62.69%), Postives = 48/67 (71.64%), Query Frame = 2 
Query:  296 ANISERMKKKRSRAAFSHNQVYELERRFSHQTYLSGPERTELARSLKLTENQVKIWFQNRRYKTKKR 496
             N  +R+++K  R  FS  QVYELERRF  Q YLS PER  LA  LKLT NQVKIWFQN+RYK KK+
Sbjct:  148 GNKPKRIRRK-PRVLFSQAQVYELERRFKGQKYLSAPERDHLASLLKLTPNQVKIWFQNKRYKCKKQ 213
[Close]
BLAST of Homeobox protein Nkx-3.2 vs. Ensembl Nematostella
Match: EDO33947 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SQP6])

HSP 1 Score: 78.9518 bits (193), Expect = 5.469e-19
Identity = 40/76 (52.63%), Postives = 52/76 (68.42%), Query Frame = 2 
Query:  317 KKKRSRAAFSHNQVYELERRFSHQTYLSGPERTELARSLKLTENQVKIWFQNRRYKTKKRRQQIESEIDTKNPQNF 544
            KK++ R  F+ +Q+YELERRF +Q YLS PER +L R + LT  QVKIWFQN RYK KK+     SE + K P++ 
Sbjct:    1 KKRKRRILFTKSQIYELERRFRYQRYLSAPEREQLGRMINLTPTQVKIWFQNHRYKHKKQ----ASEGEYKEPRSI 72
[Close]
BLAST of Homeobox protein Nkx-3.2 vs. Ensembl Nematostella
Match: EDO45871 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RRR7])

HSP 1 Score: 76.2554 bits (186), Expect = 3.780e-18
Identity = 37/62 (59.68%), Postives = 45/62 (72.58%), Query Frame = 2 
Query:  320 KKRSRAAFSHNQVYELERRFSHQTYLSGPERTELARSLKLTENQVKIWFQNRRYKTKKRRQQ 505
            KK+ R  F+ +Q+YELERRF  Q YLS PER  LAR + LT  QVKIWFQN RYK ++R +Q
Sbjct:    1 KKKKRILFTRSQIYELERRFRVQQYLSAPEREHLARMISLTPVQVKIWFQNHRYKCRQRYKQ 62
[Close]
BLAST of Homeobox protein Nkx-3.2 vs. Ensembl Medaka
Match: nkx3.3 (NK3 homeobox 3 [Source:ZFIN;Acc:ZDB-GENE-050306-27])

HSP 1 Score: 115.546 bits (288), Expect = 6.658e-32
Identity = 56/94 (59.57%), Postives = 68/94 (72.34%), Query Frame = 2 
Query:  320 KKRSRAAFSHNQVYELERRFSHQTYLSGPERTELARSLKLTENQVKIWFQNRRYKTKKRRQQIESEIDTKNPQNFEIPNFPSRDLSIKDEMNNH 601
            KKRSRAAFSH QV+ELERRFS Q YLSGPER +LA +LKLTE QVKIWFQNRRYKTK+R  Q+ +E+   NP+   +       + ++DE   H
Sbjct:   10 KKRSRAAFSHTQVHELERRFSAQRYLSGPERADLAEALKLTETQVKIWFQNRRYKTKRR--QVAAEVAALNPKTVSV------KVLVRDEEKQH 95
[Close]
BLAST of Homeobox protein Nkx-3.2 vs. Ensembl Medaka
Match: nkx3-2 (NK3 homeobox 2 [Source:NCBI gene;Acc:101174110])

HSP 1 Score: 113.235 bits (282), Expect = 1.628e-29
Identity = 66/128 (51.56%), Postives = 86/128 (67.19%), Query Frame = 2 
Query:  152 ENLLSETTYENDDISENIDSDVESYFSNDSDLEVSKSSMIVDHHKIQPANISERMKKKRSRAAFSHNQVYELERRFSHQTYLSGPERTELARSLKLTENQVKIWFQNRRYKTKKRRQQIESEIDTKNP 535
            E+L  ET +E+   ++N+ SD +   +NDS       S + +    QP     + +KKRSRAAFSH QV+ELERRF+HQ YLSGPER +LA SLKLTE QVKIWFQNRRYKTK+R  Q+ +++    P
Sbjct:   98 ESLQEETDHESG-AADNVKSDSDP--NNDS-------SNLDEKSPDQP-----KQRKKRSRAAFSHAQVFELERRFNHQRYLSGPERADLAASLKLTETQVKIWFQNRRYKTKRR--QMAADLMASTP 208
[Close]
BLAST of Homeobox protein Nkx-3.2 vs. Ensembl Medaka
Match: nkx3-1 (homeobox protein Nkx-3.1-like [Source:NCBI gene;Acc:101167461])

HSP 1 Score: 101.293 bits (251), Expect = 8.013e-26
Identity = 47/71 (66.20%), Postives = 58/71 (81.69%), Query Frame = 2 
Query:  299 NISERMKKKRSRAAFSHNQVYELERRFSHQTYLSGPERTELARSLKLTENQVKIWFQNRRYKTKKRRQQIE 511
            N++   K+KRSRAAF+H QV ELE++F+HQ YLS PER  LA SL+LTE QVKIWFQNRRYKTK+++Q  E
Sbjct:   70 NLNSTGKQKRSRAAFTHLQVLELEKKFNHQKYLSAPERAHLATSLRLTETQVKIWFQNRRYKTKRKQQTSE 140
[Close]
BLAST of Homeobox protein Nkx-3.2 vs. Ensembl Medaka
Match: nkx2.7 (NK2 transcription factor related 7 [Source:ZFIN;Acc:ZDB-GENE-990415-179])

HSP 1 Score: 88.1965 bits (217), Expect = 2.629e-21
Identity = 50/119 (42.02%), Postives = 59/119 (49.58%), Query Frame = 2 
Query:  332 RAAFSHNQVYELERRFSHQTYLSGPERTELARSLKLTENQVKIWFQNRRYKTKKRRQQIESEID--TKNPQNFEIPNF-----------PSRDLSIKDEMNNHSFNTNGSVNGFGSHCY 649
            R  FS +QV ELERRF  Q YLS PER  LA  LKLT  QVKIWFQNRRYK K++RQ    E+      P+   +P             PS   ++     N      GS+   G H Y
Sbjct:   21 RVLFSQSQVSELERRFRQQRYLSAPEREHLAHVLKLTSTQVKIWFQNRRYKCKRQRQDKSLELAGYPSAPRRVAVPVLVRDGRLCSAGAPSAPYNVTVGHYNAVLGCGGSLYDCGCHSY 139
[Close]
BLAST of Homeobox protein Nkx-3.2 vs. Ensembl Medaka
Match: NKX2-3 (homeobox protein Nkx-2.5-like [Source:NCBI gene;Acc:111947865])

HSP 1 Score: 92.0485 bits (227), Expect = 4.203e-21
Identity = 41/61 (67.21%), Postives = 47/61 (77.05%), Query Frame = 2 
Query:  320 KKRSRAAFSHNQVYELERRFSHQTYLSGPERTELARSLKLTENQVKIWFQNRRYKTKKRRQ 502
            ++R R  FS  QV+ELERRF  Q YLS PER  LA +LKLT NQVKIWFQNRRYK K++RQ
Sbjct:  168 RRRPRVLFSQAQVFELERRFKQQRYLSAPEREHLATTLKLTSNQVKIWFQNRRYKCKRQRQ 228
[Close]
BLAST of Homeobox protein Nkx-3.2 vs. Planmine SMEST
Match: SMESG000027004.1 (SMESG000027004.1)

HSP 1 Score: 490.73 bits (1262), Expect = 4.671e-178
Identity = 236/239 (98.74%), Postives = 239/239 (100.00%), Query Frame = 2 
Query:  125 MMRKSTFLIENLLSETTYENDDISENIDSDVESYFSNDSDLEVSKSSMIVDHHKIQPANISERMKKKRSRAAFSHNQVYELERRFSHQTYLSGPERTELARSLKLTENQVKIWFQNRRYKTKKRRQQIESEIDTKNPQNFEIPNFPSRDLSIKDEMNNHSFNTNGSVNGFGSHCYYNSVIDSLLRSSPYGGASKSFFHNMNTGNSFQMTPNSYQMTMSMLQMMKKKGFNSSLVSNMTPS 841
            MMRKSTFLIENLLSETTYENDDISENIDSDVESYFSNDSDLEVSKSSMIVDHHKIQPANISERMKKKRSRAAFSHNQVYELERRFSHQTYLSGPERTELARSLKLTENQVKIWFQNRRYKTKKRRQQIESEIDTKNPQNFEIPNFPSRDLSIKDEMNNHSF+TNGSVNGFGSHCYYNSVIDSLLRSSPYGGASKSFFHNMNTGNSFQMTPNSYQMTMSMLQMMK+KGF+SSLVSNMTPS
Sbjct:    1 MMRKSTFLIENLLSETTYENDDISENIDSDVESYFSNDSDLEVSKSSMIVDHHKIQPANISERMKKKRSRAAFSHNQVYELERRFSHQTYLSGPERTELARSLKLTENQVKIWFQNRRYKTKKRRQQIESEIDTKNPQNFEIPNFPSRDLSIKDEMNNHSFSTNGSVNGFGSHCYYNSVIDSLLRSSPYGGASKSFFHNMNTGNSFQMTPNSYQMTMSMLQMMKRKGFDSSLVSNMTPS 239
[Close]
BLAST of Homeobox protein Nkx-3.2 vs. Planmine SMEST
Match: SMESG000027004.1 (SMESG000027004.1)

HSP 1 Score: 488.804 bits (1257), Expect = 2.492e-177
Identity = 235/238 (98.74%), Postives = 238/238 (100.00%), Query Frame = 2 
Query:  128 MRKSTFLIENLLSETTYENDDISENIDSDVESYFSNDSDLEVSKSSMIVDHHKIQPANISERMKKKRSRAAFSHNQVYELERRFSHQTYLSGPERTELARSLKLTENQVKIWFQNRRYKTKKRRQQIESEIDTKNPQNFEIPNFPSRDLSIKDEMNNHSFNTNGSVNGFGSHCYYNSVIDSLLRSSPYGGASKSFFHNMNTGNSFQMTPNSYQMTMSMLQMMKKKGFNSSLVSNMTPS 841
            MRKSTFLIENLLSETTYENDDISENIDSDVESYFSNDSDLEVSKSSMIVDHHKIQPANISERMKKKRSRAAFSHNQVYELERRFSHQTYLSGPERTELARSLKLTENQVKIWFQNRRYKTKKRRQQIESEIDTKNPQNFEIPNFPSRDLSIKDEMNNHSF+TNGSVNGFGSHCYYNSVIDSLLRSSPYGGASKSFFHNMNTGNSFQMTPNSYQMTMSMLQMMK+KGF+SSLVSNMTPS
Sbjct:    1 MRKSTFLIENLLSETTYENDDISENIDSDVESYFSNDSDLEVSKSSMIVDHHKIQPANISERMKKKRSRAAFSHNQVYELERRFSHQTYLSGPERTELARSLKLTENQVKIWFQNRRYKTKKRRQQIESEIDTKNPQNFEIPNFPSRDLSIKDEMNNHSFSTNGSVNGFGSHCYYNSVIDSLLRSSPYGGASKSFFHNMNTGNSFQMTPNSYQMTMSMLQMMKRKGFDSSLVSNMTPS 238
[Close]
BLAST of Homeobox protein Nkx-3.2 vs. Planmine SMEST
Match: SMESG000062916.1 (SMESG000062916.1)

HSP 1 Score: 83.5741 bits (205), Expect = 1.231e-18
Identity = 36/65 (55.38%), Postives = 49/65 (75.38%), Query Frame = 2 
Query:  317 KKKRSRAAFSHNQVYELERRFSHQTYLSGPERTELARSLKLTENQVKIWFQNRRYKTKKRRQQIE 511
            ++++ R  FS +QVYELER+F HQ YLS  ER +LA+++ LT NQVKIWFQN RYK K+  + +E
Sbjct:  129 QRRKRRILFSQSQVYELERKFKHQKYLSASERDQLAQTINLTPNQVKIWFQNHRYKCKRIEKDME 193
[Close]
BLAST of Homeobox protein Nkx-3.2 vs. Planmine SMEST
Match: SMESG000037282.1 (SMESG000037282.1)

HSP 1 Score: 84.7297 bits (208), Expect = 1.275e-18
Identity = 45/83 (54.22%), Postives = 53/83 (63.86%), Query Frame = 2 
Query:  275 DHHK--IQPANISERMKKKRSRAAFSHNQVYELERRFSHQTYLSGPERTELARSLKLTENQVKIWFQNRRYKTKKRRQQIESE 517
            +H K  IQ  NIS+R K+   R  FS  Q+YELERRF  Q YLS PER  LA  + LT  QVKIWFQN RYK K+ ++  E E
Sbjct:  119 EHQKASIQFNNISQRRKR---RILFSQAQIYELERRFKQQKYLSAPEREHLANLINLTPTQVKIWFQNHRYKCKRSQKDKEKE 198
[Close]
BLAST of Homeobox protein Nkx-3.2 vs. Planmine SMEST
Match: SMESG000037282.1 (SMESG000037282.1)

HSP 1 Score: 84.7297 bits (208), Expect = 1.397e-18
Identity = 45/83 (54.22%), Postives = 53/83 (63.86%), Query Frame = 2 
Query:  275 DHHK--IQPANISERMKKKRSRAAFSHNQVYELERRFSHQTYLSGPERTELARSLKLTENQVKIWFQNRRYKTKKRRQQIESE 517
            +H K  IQ  NIS+R K+   R  FS  Q+YELERRF  Q YLS PER  LA  + LT  QVKIWFQN RYK K+ ++  E E
Sbjct:  110 EHQKASIQFNNISQRRKR---RILFSQAQIYELERRFKQQKYLSAPEREHLANLINLTPTQVKIWFQNHRYKCKRSQKDKEKE 189
The following BLAST results are available for this feature:
BLAST of Homeobox protein Nkx-3.2 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
NKX3-21.265e-2866.67NK3 homeobox 2 [Source:HGNC Symbol;Acc:HGNC:951][more]
NKX3-14.394e-2769.44NK3 homeobox 1 [Source:HGNC Symbol;Acc:HGNC:7838][more]
NKX3-11.504e-2669.44NK3 homeobox 1 [Source:HGNC Symbol;Acc:HGNC:7838][more]
NKX2-39.974e-2157.50NK2 homeobox 3 [Source:HGNC Symbol;Acc:HGNC:7836][more]
NKX2-31.095e-2055.42NK2 homeobox 3 [Source:HGNC Symbol;Acc:HGNC:7836][more]
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BLAST of Homeobox protein Nkx-3.2 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ceh-91.417e-1934.64Homeobox protein ceh-9 [Source:UniProtKB/Swiss-Pr... [more]
cog-16.315e-1937.50COG-1B [Source:UniProtKB/TrEMBL;Acc:G5EGF2][more]
ceh-225.315e-1848.84Homeobox protein ceh-22 [Source:UniProtKB/Swiss-P... [more]
ceh-225.692e-1848.84Homeobox protein ceh-22 [Source:UniProtKB/Swiss-P... [more]
ceh-229.161e-1848.84Homeobox protein ceh-22 [Source:UniProtKB/Swiss-P... [more]
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BLAST of Homeobox protein Nkx-3.2 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
bap1.908e-2854.81gene:FBgn0004862 transcript:FBtr0084087[more]
scro4.519e-1752.00gene:FBgn0028993 transcript:FBtr0339923[more]
vnd5.706e-1757.35gene:FBgn0261930 transcript:FBtr0070110[more]
vnd5.787e-1754.17gene:FBgn0261930 transcript:FBtr0110929[more]
scro1.139e-1652.00gene:FBgn0028993 transcript:FBtr0113751[more]
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BLAST of Homeobox protein Nkx-3.2 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
nkx3-23.255e-2979.37NK3 homeobox 2 [Source:ZFIN;Acc:ZDB-GENE-030127-1][more]
nkx3.31.501e-2783.05NK3 homeobox 3 [Source:ZFIN;Acc:ZDB-GENE-050306-27... [more]
nkx3.31.501e-2783.05NK3 homeobox 3 [Source:ZFIN;Acc:ZDB-GENE-050306-27... [more]
nkx3.37.425e-2748.76NK3 homeobox 3 [Source:ZFIN;Acc:ZDB-GENE-050306-27... [more]
nkx3-18.882e-2746.15NK3 homeobox 1 [Source:ZFIN;Acc:ZDB-GENE-081104-23... [more]
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BLAST of Homeobox protein Nkx-3.2 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSXETT00000030786.12.853e-2880.65NK3 homeobox 2 [Source:NCBI gene;Acc:100497965][more]
ENSXETT00000032017.15.451e-2878.13NK3 homeobox 3 [Source:NCBI gene;Acc:100485176][more]
ENSXETT00000017291.18.074e-2878.13NK3 homeobox 3 [Source:NCBI gene;Acc:100485176][more]
ENSXETT00000050503.14.390e-2763.29NK3 homeobox 1 [Source:NCBI gene;Acc:100038192][more]
NKX2-39.143e-2153.09NK2 homeobox 3 [Source:NCBI gene;Acc:100486189][more]
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BLAST of Homeobox protein Nkx-3.2 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Nkx3-25.747e-2966.67NK3 homeobox 2 [Source:MGI Symbol;Acc:MGI:108015][more]
Nkx3-15.343e-2673.02NK3 homeobox 1 [Source:MGI Symbol;Acc:MGI:97352][more]
Nkx2-37.592e-2146.49NK2 homeobox 3 [Source:MGI Symbol;Acc:MGI:97348][more]
Nkx2-93.836e-2048.04NK2 homeobox 9 [Source:MGI Symbol;Acc:MGI:1270158][more]
Nkx2-54.422e-2072.22NK2 homeobox 5 [Source:MGI Symbol;Acc:MGI:97350][more]
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BLAST of Homeobox protein Nkx-3.2 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|P97503|NKX32_MOUSE4.020e-2866.67Homeobox protein Nkx-3.2 OS=Mus musculus OX=10090 ... [more]
sp|P78367|NKX32_HUMAN6.074e-2866.67Homeobox protein Nkx-3.2 OS=Homo sapiens OX=9606 G... [more]
sp|P22809|BAGP_DROME1.912e-2754.81Homeobox protein bagpipe OS=Drosophila melanogaste... [more]
sp|P70061|NKX32_XENLA2.531e-2780.65Homeobox protein Nkx-3.2 OS=Xenopus laevis OX=8355... [more]
sp|O93590|ZAX_XENLA2.740e-2758.59Homeobox protein zampogna OS=Xenopus laevis OX=835... [more]
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BLAST of Homeobox protein Nkx-3.2 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A3B3BB186.956e-2950.00NK3 homeobox 3 OS=Oryzias melastigma OX=30732 PE=4... [more]
A0A182P3Z11.171e-2859.26Protein bagpipe OS=Anopheles epiroticus OX=199890 ... [more]
H2LU881.769e-2859.57NK3 homeobox 3 OS=Oryzias latipes OX=8090 PE=4 SV=... [more]
A0A4Z2C4W12.582e-2853.85Homeobox domain-containing protein OS=Takifugu bim... [more]
A0A5C6MJI32.582e-2853.85Homeobox protein OS=Takifugu flavidus OX=433684 GN... [more]
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BLAST of Homeobox protein Nkx-3.2 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
nkx3-21.117e-2960.64homeobox protein Nkx-3.2 [Source:NCBI gene;Acc:103... [more]
nkx3-25.207e-2980.65homeobox protein Nkx-3.2 [Source:NCBI gene;Acc:103... [more]
nkx3.31.693e-2676.12homeobox protein Nkx-3.2-like [Source:NCBI gene;Ac... [more]
nkx3-12.084e-2470.15NK3 homeobox 1 [Source:NCBI gene;Acc:103038181][more]
ENSAMXT00000002203.21.835e-2057.33pep primary_assembly:Astyanax_mexicanus-2.0:9:2091... [more]
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BLAST of Homeobox protein Nkx-3.2 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSPMAT00000005776.19.365e-1963.93pep scaffold:Pmarinus_7.0:GL477528:542110:542457:1... [more]
nkx2.18.272e-1859.32NK2 homeobox 1 [Source:ZFIN;Acc:ZDB-GENE-010404-1][more]
ENSPMAT00000001141.12.291e-1761.02pep scaffold:Pmarinus_7.0:GL478075:36995:38394:-1 ... [more]
ENSPMAT00000001480.11.297e-1552.63pep scaffold:Pmarinus_7.0:GL487501:66:2428:-1 gene... [more]
HMX15.084e-1558.62H6 family homeobox 1 [Source:HGNC Symbol;Acc:HGNC:... [more]
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BLAST of Homeobox protein Nkx-3.2 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Homeobox protein Nkx-3.2 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
NK-31.258e-3146.48Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO339463.788e-2139.10Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
NK-46.782e-2062.69NK-4 homeobox protein; Predicted protein [Source:... [more]
EDO339475.469e-1952.63Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO458713.780e-1859.68Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Homeobox protein Nkx-3.2 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
nkx3.36.658e-3259.57NK3 homeobox 3 [Source:ZFIN;Acc:ZDB-GENE-050306-27... [more]
nkx3-21.628e-2951.56NK3 homeobox 2 [Source:NCBI gene;Acc:101174110][more]
nkx3-18.013e-2666.20homeobox protein Nkx-3.1-like [Source:NCBI gene;Ac... [more]
nkx2.72.629e-2142.02NK2 transcription factor related 7 [Source:ZFIN;Ac... [more]
NKX2-34.203e-2167.21homeobox protein Nkx-2.5-like [Source:NCBI gene;Ac... [more]
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BLAST of Homeobox protein Nkx-3.2 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000027004.14.671e-17898.74SMESG000027004.1[more]
SMESG000027004.12.492e-17798.74SMESG000027004.1[more]
SMESG000062916.11.231e-1855.38SMESG000062916.1[more]
SMESG000037282.11.275e-1854.22SMESG000037282.1[more]
SMESG000037282.11.397e-1854.22SMESG000037282.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30008363 ID=SMED30008363|Name=Homeobox protein Nkx-3.2|organism=Schmidtea mediterranea sexual|type=transcript|length=843bp
AATTATATGTGTTTGTGTGCGTGCAAGAAATCGACCAATCAAATATTTCT
TATTCATAAAAAGTGCTTAAAATCTTGAATCCAAAATTTAATTAGTATTT
TATTTTGTTGTTGATAAATTCAAGATGATGCGAAAGAGCACATTTTTAAT
TGAGAATTTATTGAGTGAAACTACTTACGAAAATGACGACATCAGCGAAA
ACATTGACAGCGATGTGGAATCGTATTTCAGTAACGATAGCGATTTAGAA
GTGTCCAAGAGCTCCATGATAGTAGATCATCATAAAATCCAACCAGCAAA
CATTTCGGAACGAATGAAAAAAAAACGTTCAAGAGCGGCATTTTCTCATA
ATCAAGTTTATGAATTGGAAAGGCGATTTAGCCATCAAACGTATCTTTCC
GGGCCCGAACGAACTGAGCTGGCTCGAAGTTTGAAGTTGACAGAAAATCA
AGTGAAAATTTGGTTTCAAAATCGGCGTTATAAAACAAAAAAGCGACGAC
AACAAATAGAGTCAGAAATCGATACGAAAAACCCTCAGAATTTTGAAATT
CCGAATTTCCCATCTCGAGATTTGTCTATCAAAGATGAAATGAACAACCA
TTCATTCAACACCAACGGATCGGTGAATGGGTTCGGCAGTCATTGTTATT
ATAACAGTGTGATAGATTCACTTCTTCGATCATCACCGTATGGAGGAGCT
AGTAAATCGTTTTTTCATAATATGAACACCGGAAATTCATTTCAAATGAC
CCCTAACTCGTATCAGATGACAATGTCCATGCTTCAAATGATGAAAAAGA
AAGGCTTCAATTCGTCTCTTGTTTCAAACATGACACCTTCACT
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protein sequence of SMED30008363-orf-1

>SMED30008363-orf-1 ID=SMED30008363-orf-1|Name=SMED30008363-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=239bp
MMRKSTFLIENLLSETTYENDDISENIDSDVESYFSNDSDLEVSKSSMIV
DHHKIQPANISERMKKKRSRAAFSHNQVYELERRFSHQTYLSGPERTELA
RSLKLTENQVKIWFQNRRYKTKKRRQQIESEIDTKNPQNFEIPNFPSRDL
SIKDEMNNHSFNTNGSVNGFGSHCYYNSVIDSLLRSSPYGGASKSFFHNM
NTGNSFQMTPNSYQMTMSMLQMMKKKGFNSSLVSNMTPS
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000016pharynx
Vocabulary: INTERPRO
TermDefinition
IPR020479Homeobox_metazoa
IPR001356Homeobox_dom
IPR009057Homeobox-like_sf
IPR017970Homeobox_CS
Vocabulary: molecular function
TermDefinition
GO:0003677DNA binding
GO:0043565sequence-specific DNA binding
Vocabulary: biological process
TermDefinition
GO:0006355regulation of transcription, DNA-templated
Vocabulary: cellular component
TermDefinition
GO:0005634nucleus
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR020479Homeobox domain, metazoaPRINTSPR00024HOMEOBOXcoord: 103..113
score: 66.2
coord: 88..99
score: 41.89
coord: 113..122
score: 76.99
IPR001356Homeobox domainSMARTSM00389HOX_1coord: 66..128
e-value: 3.2E-22
score: 89.8
IPR001356Homeobox domainPFAMPF00046Homeodomaincoord: 67..123
e-value: 2.1E-20
score: 72.3
IPR001356Homeobox domainPROSITEPS50071HOMEOBOX_2coord: 64..124
score: 20.844
IPR001356Homeobox domainCDDcd00086homeodomaincoord: 67..125
e-value: 4.32298E-20
score: 78.8244
NoneNo IPR availableGENE3DG3DSA:1.10.10.60coord: 33..126
e-value: 1.0E-23
score: 85.3
NoneNo IPR availablePANTHERPTHR24340FAMILY NOT NAMEDcoord: 24..132
NoneNo IPR availablePANTHERPTHR24340:SF73HOMEOBOX PROTEIN BAGPIPEcoord: 24..132
IPR017970Homeobox, conserved sitePROSITEPS00027HOMEOBOX_1coord: 99..122
IPR009057Homeobox-like domain superfamilySUPERFAMILYSSF46689Homeodomain-likecoord: 51..125