Fatty acid synthase

Overview
NameFatty acid synthase
Smed IDSMED30008325
Length (bp)2662
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Fatty acid synthase (SMED30008325) t-SNE clustered cells

Violin plots show distribution of expression levels for Fatty acid synthase (SMED30008325) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Fatty acid synthase (SMED30008325) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Fatty acid synthase (SMED30008325) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30008325

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 11

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
head regionSMED30008325h1SMcG0015127 SmedASXL_016145SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016		whole organism asexual adult RNA-sequencing evidence
pharynxSMED30008325h1SMcG0015127 dd_Smed_v4_10967_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
protonephridiaSMED30008325h1SMcG0015127 dd_Smed_v4_10967_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
nervous systemSMED30008325h1SMcG0015127 dd_Smed_v4_10967_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30008325h1SMcG0015127 dd_Smed_v4_10967_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neuronSMED30008325h1SMcG0015127 dd_Smed_v4_10967_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		whole organism asexual adult colorimetric in situ hybridization evidence
neoblastSMED30008325h1SMcG0015127 dd_Smed_v4_10967_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
head regionSMED30008325h1SMcG0015127 dd_Smed_v6_10967_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017		whole organism asexual adult RNA-sequencing evidence
reproductive organSMED30008325h1SMcG0015127 Contig29241uc_Smed_v2PMID:28434803
Rouhana et al., 2017		whole organism adult hermaphrodite RNA-sequencing evidence
reproductive organSMED30008325h1SMcG0015127 Contig29241newmark_estsPMID:28434803
Rouhana et al., 2017		whole organism adult hermaphrodite RNA-sequencing evidence
epidermisSMED30008325h1SMcG0015127 dd_Smed_v4_10967_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017		whole organism asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Fatty acid synthase vs. Ensembl Celegans
Match: epi-1 (Laminin-like protein epi-1 [Source:UniProtKB/Swiss-Prot;Acc:Q21313])

HSP 1 Score: 54.6842 bits (130), Expect = 4.382e-7
Identity = 88/454 (19.38%), Postives = 177/454 (38.99%), Query Frame = 3 
Query:  465 VVKELERKIIQLESETKEKQYALMADVEETLRSREGELKRKTEQVHTEMLNYELKYRLASKELDLTRISKAEILRNLTEKENRIRELEMKLTEIELANKSEISIEKMKRETEAVHAKENQTNLLKEIENLTRRINEKNNKLKSKIETAKKLENEIKSVLNAARXXXXXXXXXXXXXXXXXXXXXNKMKELANQVEKEKENISAKDSEIARLVSRMTGENLKKETD---------------LRNAKFEIENLVEQLRKKQEEMLELRNELEYAVCKDLEISKIKEGEKENWESKLQRVRIEEMAKVESMIKALTKSRDESIAEVRELRQQLEEKRQVRLCSNCSNESVKNSRINESKDEQIVIKELNSQNAKLKEIIAKMTEETTNQVSNQPPETISNNRHIASLAERNRQLQQEKIDLLATSRKLQARFEATESDNNNMKRLVREKDTEISQIK 1781
            ++KE E  ++ LE+ + ++       V   L   + +++ +TE++  +   +E + + A +EL     S  ++L+    K ++   +   L   ++ N      + ++R  EA   +  + N+   I N+T  + +K  ++   + T  +  N++   L AA++                     +++     V+ +  N  A +  +     R T +N K  TD               L+NAK +I+N  E L              E A  + ++ ++ K    E  E                 I AL+K+  + + E  +L++QLE+  ++        E+VK      SK+    I E   +  KLK  I    EET  ++S    +         S  E  R  ++  + L   +  + ++FE  +  ++     V     ++SQIK
Sbjct: 2268 LLKEAEETLMTLEAASADQYPEKAQTVPGKLEEIQKKIQEETEKLDKQKETFEAQKKRA-EELAAYLNSAQQLLKESKSKADKSNNIAKMLQLTKVENLVAAITDDLER-VEAAKGEFQKLNV--AIGNITENLKDKREEMTHAVTTLNETRNDVAEALEAAKK---------------------RVRRDEKSVDMQLVNAKAHELHLQATTLRQTFDNNKDNTDQAVEAANAFSNLTDTLKNAKAQIDNAYEALSA------------EPAFAESVQNARDKPFPDETKEK----------------IDALSKTVSQDLKETEKLKKQLEQLTELSEKLRKRKEAVKAGIPKYSKNTLDSIDEKVQEVEKLKAEIDANIEETRAKISEIAGKAEEITEKANSAMEGIRLARRNSVQLNKLAPVIVSKFEELKKLSSARSAKVDSVSDKVSQIK 2668
[Close]
BLAST of Fatty acid synthase vs. Ensembl Celegans
Match: epi-1 (Laminin-like protein epi-1 [Source:UniProtKB/Swiss-Prot;Acc:Q21313])

HSP 1 Score: 54.6842 bits (130), Expect = 4.384e-7
Identity = 88/454 (19.38%), Postives = 177/454 (38.99%), Query Frame = 3 
Query:  465 VVKELERKIIQLESETKEKQYALMADVEETLRSREGELKRKTEQVHTEMLNYELKYRLASKELDLTRISKAEILRNLTEKENRIRELEMKLTEIELANKSEISIEKMKRETEAVHAKENQTNLLKEIENLTRRINEKNNKLKSKIETAKKLENEIKSVLNAARXXXXXXXXXXXXXXXXXXXXXNKMKELANQVEKEKENISAKDSEIARLVSRMTGENLKKETD---------------LRNAKFEIENLVEQLRKKQEEMLELRNELEYAVCKDLEISKIKEGEKENWESKLQRVRIEEMAKVESMIKALTKSRDESIAEVRELRQQLEEKRQVRLCSNCSNESVKNSRINESKDEQIVIKELNSQNAKLKEIIAKMTEETTNQVSNQPPETISNNRHIASLAERNRQLQQEKIDLLATSRKLQARFEATESDNNNMKRLVREKDTEISQIK 1781
            ++KE E  ++ LE+ + ++       V   L   + +++ +TE++  +   +E + + A +EL     S  ++L+    K ++   +   L   ++ N      + ++R  EA   +  + N+   I N+T  + +K  ++   + T  +  N++   L AA++                     +++     V+ +  N  A +  +     R T +N K  TD               L+NAK +I+N  E L              E A  + ++ ++ K    E  E                 I AL+K+  + + E  +L++QLE+  ++        E+VK      SK+    I E   +  KLK  I    EET  ++S    +         S  E  R  ++  + L   +  + ++FE  +  ++     V     ++SQIK
Sbjct: 2268 LLKEAEETLMTLEAASADQYPEKAQTVPGKLEEIQKKIQEETEKLDKQKETFEAQKKRA-EELAAYLNSAQQLLKESKSKADKSNNIAKMLQLTKVENLVAAITDDLER-VEAAKGEFQKLNV--AIGNITENLKDKREEMTHAVTTLNETRNDVAEALEAAKK---------------------RVRRDEKSVDMQLVNAKAHELHLQATTLRQTFDNNKDNTDQAVEAANAFSNLTDTLKNAKAQIDNAYEALSA------------EPAFAESVQNARDKPFPDETKEK----------------IDALSKTVSQDLKETEKLKKQLEQLTELSEKLRKRKEAVKAGIPKYSKNTLDSIDEKVQEVEKLKAEIDANIEETRAKISEIAGKAEEITEKANSAMEGIRLARRNSVQLNKLAPVIVSKFEELKKLSSARSAKVDSVSDKVSQIK 2668
[Close]
BLAST of Fatty acid synthase vs. Ensembl Celegans
Match: epi-1 (Laminin-like protein epi-1 [Source:UniProtKB/Swiss-Prot;Acc:Q21313])

HSP 1 Score: 54.6842 bits (130), Expect = 4.386e-7
Identity = 88/454 (19.38%), Postives = 177/454 (38.99%), Query Frame = 3 
Query:  465 VVKELERKIIQLESETKEKQYALMADVEETLRSREGELKRKTEQVHTEMLNYELKYRLASKELDLTRISKAEILRNLTEKENRIRELEMKLTEIELANKSEISIEKMKRETEAVHAKENQTNLLKEIENLTRRINEKNNKLKSKIETAKKLENEIKSVLNAARXXXXXXXXXXXXXXXXXXXXXNKMKELANQVEKEKENISAKDSEIARLVSRMTGENLKKETD---------------LRNAKFEIENLVEQLRKKQEEMLELRNELEYAVCKDLEISKIKEGEKENWESKLQRVRIEEMAKVESMIKALTKSRDESIAEVRELRQQLEEKRQVRLCSNCSNESVKNSRINESKDEQIVIKELNSQNAKLKEIIAKMTEETTNQVSNQPPETISNNRHIASLAERNRQLQQEKIDLLATSRKLQARFEATESDNNNMKRLVREKDTEISQIK 1781
            ++KE E  ++ LE+ + ++       V   L   + +++ +TE++  +   +E + + A +EL     S  ++L+    K ++   +   L   ++ N      + ++R  EA   +  + N+   I N+T  + +K  ++   + T  +  N++   L AA++                     +++     V+ +  N  A +  +     R T +N K  TD               L+NAK +I+N  E L              E A  + ++ ++ K    E  E                 I AL+K+  + + E  +L++QLE+  ++        E+VK      SK+    I E   +  KLK  I    EET  ++S    +         S  E  R  ++  + L   +  + ++FE  +  ++     V     ++SQIK
Sbjct: 2288 LLKEAEETLMTLEAASADQYPEKAQTVPGKLEEIQKKIQEETEKLDKQKETFEAQKKRA-EELAAYLNSAQQLLKESKSKADKSNNIAKMLQLTKVENLVAAITDDLER-VEAAKGEFQKLNV--AIGNITENLKDKREEMTHAVTTLNETRNDVAEALEAAKK---------------------RVRRDEKSVDMQLVNAKAHELHLQATTLRQTFDNNKDNTDQAVEAANAFSNLTDTLKNAKAQIDNAYEALSA------------EPAFAESVQNARDKPFPDETKEK----------------IDALSKTVSQDLKETEKLKKQLEQLTELSEKLRKRKEAVKAGIPKYSKNTLDSIDEKVQEVEKLKAEIDANIEETRAKISEIAGKAEEITEKANSAMEGIRLARRNSVQLNKLAPVIVSKFEELKKLSSARSAKVDSVSDKVSQIK 2688
[Close]
BLAST of Fatty acid synthase vs. Ensembl Celegans
Match: epi-1 (Laminin-like protein epi-1 [Source:UniProtKB/Swiss-Prot;Acc:Q21313])

HSP 1 Score: 54.299 bits (129), Expect = 4.420e-7
Identity = 88/454 (19.38%), Postives = 177/454 (38.99%), Query Frame = 3 
Query:  465 VVKELERKIIQLESETKEKQYALMADVEETLRSREGELKRKTEQVHTEMLNYELKYRLASKELDLTRISKAEILRNLTEKENRIRELEMKLTEIELANKSEISIEKMKRETEAVHAKENQTNLLKEIENLTRRINEKNNKLKSKIETAKKLENEIKSVLNAARXXXXXXXXXXXXXXXXXXXXXNKMKELANQVEKEKENISAKDSEIARLVSRMTGENLKKETD---------------LRNAKFEIENLVEQLRKKQEEMLELRNELEYAVCKDLEISKIKEGEKENWESKLQRVRIEEMAKVESMIKALTKSRDESIAEVRELRQQLEEKRQVRLCSNCSNESVKNSRINESKDEQIVIKELNSQNAKLKEIIAKMTEETTNQVSNQPPETISNNRHIASLAERNRQLQQEKIDLLATSRKLQARFEATESDNNNMKRLVREKDTEISQIK 1781
            ++KE E  ++ LE+ + ++       V   L   + +++ +TE++  +   +E + + A +EL     S  ++L+    K ++   +   L   ++ N      + ++R  EA   +  + N+   I N+T  + +K  ++   + T  +  N++   L AA++                     +++     V+ +  N  A +  +     R T +N K  TD               L+NAK +I+N  E L              E A  + ++ ++ K    E  E                 I AL+K+  + + E  +L++QLE+  ++        E+VK      SK+    I E   +  KLK  I    EET  ++S    +         S  E  R  ++  + L   +  + ++FE  +  ++     V     ++SQIK
Sbjct: 2277 LLKEAEETLMTLEAASADQYPEKAQTVPGKLEEIQKKIQEETEKLDKQKETFEAQKKRA-EELAAYLNSAQQLLKESKSKADKSNNIAKMLQLTKVENLVAAITDDLER-VEAAKGEFQKLNV--AIGNITENLKDKREEMTHAVTTLNETRNDVAEALEAAKK---------------------RVRRDEKSVDMQLVNAKAHELHLQATTLRQTFDNNKDNTDQAVEAANAFSNLTDTLKNAKAQIDNAYEALSA------------EPAFAESVQNARDKPFPDETKEK----------------IDALSKTVSQDLKETEKLKKQLEQLTELSEKLRKRKEAVKAGIPKYSKNTLDSIDEKVQEVEKLKAEIDANIEETRAKISEIAGKAEEITEKANSAMEGIRLARRNSVQLNKLAPVIVSKFEELKKLSSARSAKVDSVSDKVSQIK 2677
[Close]
BLAST of Fatty acid synthase vs. Ensembl Celegans
Match: epi-1 (Laminin-like protein epi-1 [Source:UniProtKB/Swiss-Prot;Acc:Q21313])

HSP 1 Score: 54.299 bits (129), Expect = 4.420e-7
Identity = 88/454 (19.38%), Postives = 177/454 (38.99%), Query Frame = 3 
Query:  465 VVKELERKIIQLESETKEKQYALMADVEETLRSREGELKRKTEQVHTEMLNYELKYRLASKELDLTRISKAEILRNLTEKENRIRELEMKLTEIELANKSEISIEKMKRETEAVHAKENQTNLLKEIENLTRRINEKNNKLKSKIETAKKLENEIKSVLNAARXXXXXXXXXXXXXXXXXXXXXNKMKELANQVEKEKENISAKDSEIARLVSRMTGENLKKETD---------------LRNAKFEIENLVEQLRKKQEEMLELRNELEYAVCKDLEISKIKEGEKENWESKLQRVRIEEMAKVESMIKALTKSRDESIAEVRELRQQLEEKRQVRLCSNCSNESVKNSRINESKDEQIVIKELNSQNAKLKEIIAKMTEETTNQVSNQPPETISNNRHIASLAERNRQLQQEKIDLLATSRKLQARFEATESDNNNMKRLVREKDTEISQIK 1781
            ++KE E  ++ LE+ + ++       V   L   + +++ +TE++  +   +E + + A +EL     S  ++L+    K ++   +   L   ++ N      + ++R  EA   +  + N+   I N+T  + +K  ++   + T  +  N++   L AA++                     +++     V+ +  N  A +  +     R T +N K  TD               L+NAK +I+N  E L              E A  + ++ ++ K    E  E                 I AL+K+  + + E  +L++QLE+  ++        E+VK      SK+    I E   +  KLK  I    EET  ++S    +         S  E  R  ++  + L   +  + ++FE  +  ++     V     ++SQIK
Sbjct: 2288 LLKEAEETLMTLEAASADQYPEKAQTVPGKLEEIQKKIQEETEKLDKQKETFEAQKKRA-EELAAYLNSAQQLLKESKSKADKSNNIAKMLQLTKVENLVAAITDDLER-VEAAKGEFQKLNV--AIGNITENLKDKREEMTHAVTTLNETRNDVAEALEAAKK---------------------RVRRDEKSVDMQLVNAKAHELHLQATTLRQTFDNNKDNTDQAVEAANAFSNLTDTLKNAKAQIDNAYEALSA------------EPAFAESVQNARDKPFPDETKEK----------------IDALSKTVSQDLKETEKLKKQLEQLTELSEKLRKRKEAVKAGIPKYSKNTLDSIDEKVQEVEKLKAEIDANIEETRAKISEIAGKAEEITEKANSAMEGIRLARRNSVQLNKLAPVIVSKFEELKKLSSARSAKVDSVSDKVSQIK 2688
[Close]
BLAST of Fatty acid synthase vs. Ensembl Zebrafish
Match: fasn (fatty acid synthase [Source:ZFIN;Acc:ZDB-GENE-030131-7802])

HSP 1 Score: 63.1586 bits (152), Expect = 1.258e-9
Identity = 99/392 (25.26%), Postives = 159/392 (40.56%), Query Frame = 3 
Query: 1284 NWESKLQRVRIEEMAKVESMIKALTKSRDESIAEVRELRQQLEE----------KRQVRLCSN-CSNESVKNSRINESKDEQIVIKELNSQNAKLK----------EIIAKMTEETTNQVSNQPPETISNN---------------------------------------------------RHIASLAERNRQLQQEKIDLLATSRKLQARFEATESDNNNMKRLVREKDTEISQIKFELDSLQRHTGMDVRTMRRTLQELETELAVSRKEAEEYYKGNLELGRVIEDLQSELTFLKSEQIERMPTLNFGAQEMLIEQLKNEISELRRKLIYTSEDDIRENKTDDKENTFLKKKLKAAANQIKNLASEKQVLIQISNRLRAELKQAGVKLP 2243
            +WE + + VR E   + E +I+ LT++RD+  AE+RE  ++L+E          +R   LC N  +    + S I+ S      I+ L  QN  LK          EI++K         +N  P T  +                                                     HI SL E    L+ EK+   A  +K + R    ES    + +    K  E   +  EL + +R    +   +++ +   E EL   R+EAEE+ KG+L        L ++++ LK +   R   +     EM ++QL+ E +   RK +       R +   D     L+ KLK AA  I  L+ +KQ LI++ NRLRA+L +AG+ +P
Sbjct:  426 DWERRCEDVRSEHYLRSEEIIQNLTQARDQVTAELREKERELQETMTVLQSVTVERDQALCGNKPALTGFQTSVIDGSSFPSEEIRRLQQQNNTLKAVVAEMRKEMEILSKQRLAAPRPATNLEPSTAGSTDYTKALEKEILELKAKCRNLEERLEESSKTVNTSINPTPAFPVSPDNAYLQNHIRSLNETIGGLRVEKVANAAALKKQEVRLAHLESTVEQLTQQCHSKHMENESLCLELANHKRAATAEEARLKQRVAAAELELNEVRREAEEHQKGSLLHNLETVALGNQVSALKVDLASRREPIVLNQSEM-VKQLQEE-NLSLRKQLLLLHSSSRGSSIGDV--PLLQSKLKQAARMISGLSQDKQQLIEMGNRLRAQLIEAGLDVP 813
[Close]
BLAST of Fatty acid synthase vs. Ensembl Xenopus
Match: CCDC57 (coiled-coil domain containing 57 [Source:NCBI gene;Acc:100487204])

HSP 1 Score: 87.8113 bits (216), Expect = 4.966e-17
Identity = 192/794 (24.18%), Postives = 364/794 (45.84%), Query Frame = 3 
Query:   48 IIFQKEKEWKDL--LLVQLEKSKIERNKAEIALGEFQEKFFQLEIDFKHNLKXXXXXXXXXXXXXXXXXXXXXSVYENEEKISLLSVEVDKLKMELQMSNETKEDLRNKMKQVIDKAFNDSQSLKNEKIKEIQRIKDGNATVVKELERKIIQLESETKEKQYALMADVEETLRSREGELKRKTEQVHTEMLNYELKYRLASKELDLTR---------ISKAEI---------------LRNLTE-KENRIRELEMKLTEIELANKSEISIEKMKRETEAVHAKENQTNLLKEIENLTRRINEKNNKLKSKIETAKKLENEIKSVLNAARXXXXXXXXXXXXXXXXXXXXXNKMKELANQVEKEKENISAKDSEIARLVSRMTGENLKKETDLRNAKFEIENLVEQLRKKQEEMLELRNELEYAVCKDLEISKIKEGEKENWESKLQRVRIEEMAKVESMIKALTKSRDESIAEVRELRQQL------------EEKRQVRLCSNCSN-----------ESVKNSRINESKDEQIVIKELNSQNAKLKEIIAKM---TEETTNQV---SNQPPETISNNRHIASLAERNRQLQQEKIDLLATSRKLQARFEATESDNNNMKRLVREKDTEISQIKFELDSLQRHTG----MDVRTMRRTLQELETELAVSRKEAEEYYK--GNLELGRVIEDLQSELTFLKSEQIERMPTLNFGAQEMLIEQLKNEISELRRKLIYTSEDDIRENKTDDKENTFLKKKLKAAANQIKNLASEKQVLIQISNRLRAELKQAGVKLP 2243
            ++ +KE+EW++L  L VQ  +  +E  K E  L E +EKF  L+ DF HNLK+L ERD+E+ + E     L+    E + +IS L V+++KL+ ++Q   +  EDL++  ++ + +     +S+++ K  EI   ++G   V  +LERKI+ ++S+   ++  LM +    ++ RE E + + +++ T +L++ELK +L +KEL + R         + +AE+               L+NL+  K+ RI+ELE KL +++L  K E    + K E     A+E +++L+   E              + +E  + LE +IK  L+   E      +   + +  L   +  M      +EK K+ +    +     +++++ E++ K+  ++  K + E L  Q+ + Q+++ + + +L  AV  +  + + +   + +W+ + + V   +    E +I++L K++D+++AE++E  +++            E  + V    N              E+V+  +     D+   I++L  QNA+LK +I +M    E  + Q+   ++  P     N+  A       Q  +++I      R L+ +            R++ E+             LQ  +G    MDV         +     +S     +YYK  G L   +V     ++    ++  ++ M +     +   IEQL  EI  L+ +L     +D+      +     L  KL  AA +I  L+ EKQ LI + NRLRAEL    V  P
Sbjct:   11 LLAKKEQEWRELQQLQVQFLEMTLEDTKKE--LQEQREKFASLKKDFTHNLKVLGERDQELEQFEMMFSQLKVVESEKQARISDLRVQIEKLQQQIQKEKKKVEDLQSHYQKKLKEQHLHLESVRSSKNDEIDHCREGYEKVKCQLERKIVDVQSDLDLQKQELMLEFNTEMKKREHEFRLQLDEMSTVVLSHELKVKLLTKELSMLREKELQLLESLQQAELASEKVQEALNQKEWELKNLSAIKDARIKELEDKLQDLQLRQKKEEETFQRKYERLDHFAREKESSLISMKE--------------AHVEQVQHLEKQIKE-LHMCTETLQMENRRAQSTQQALLLEKEAM------IEKLKQEVDTVKNGWDSYITQISKESVTKDLQIQALKEDEEKLKAQITRCQKDIEKYQQQLVNAVEIERNLEEARVQAELDWQKRCELVEKTQYQHSEELIESLIKAKDQAVAELKEKERKMNKLELLVSTLSWERDKAVNFLKNYGAKLDMGEKVYLVEAVQEFQKQYPSDK---IQKLQEQNAELKNVIGQMRKEMESASEQIMPPAHDTPGASGTNKSGAVFTPDYVQSLEDEI------RTLKQKI-----------RIIEER-------------LQDESGLKEDMDV--------PVPAPAVLSENAETQYYKTTGPLRADKVASVETTKRLDAEAAHLDSMVS-QLTQKNATIEQLSKEIQTLQHQLSCKMAEDV----CPETHVYMLNNKLGEAAMKISQLSLEKQQLIDMGNRLRAELASIEVHKP 735
[Close]
BLAST of Fatty acid synthase vs. Ensembl Xenopus
Match: wdcp (WD repeat and coiled coil containing [Source:Xenbase;Acc:XB-GENE-5729803])

HSP 1 Score: 51.9878 bits (123), Expect = 5.977e-6
Identity = 111/518 (21.43%), Postives = 213/518 (41.12%), Query Frame = 3 
Query:  330 QMSNETKEDLRNKMKQVIDKA--FNDSQSLKNEKI-KEIQRIKDGNATVVKELERKIIQLESETKEKQYALMADVEETLRSREGELKRKTEQVHTEMLNYELKYRLASKELDLTRISKAEILRNLTEKENRIRELEMKLTEIELANKSEIS--IEKMKRETEAVHA----------------KENQTNLLKEIENLTRRINEKNNKLKSKI------ETAKKLENEIKSVLNAARXXX--XXXXXXXXXXXXXXXXXXNKMKELANQVEKEKENISAKDSEIARLVSRMTGENLKKETDLRNAKFEIENLVEQLRKKQEEMLELRNELEYAVCKDLEISKIKEGEKENWESKLQRVRIEEMAKVESMIKALTKSRDESIAEVRELRQQLEEKRQVRLCSNCSNESVKNSRINESKDEQIVIKELNSQNAKLKEIIAKMTEETTNQVSNQPPETISNNRHIASLAERNRQLQQEKIDLLATSRKLQARFEATESDNNNMKRLVREKDTEISQIKFELDS 1796
            Q+ +  KE LR   K + DKA   N++  + N+ + K  Q ++    +++ EL RK ++ +  T + +        E L +R  +L  +  +   E LN E+K +L   E  L  +   ++LR   E   +I+  +  L+ +   N +E+   +EK K+ETE+V                   E+ +++ KE+  LT ++NEK N L  +I      E   + EN+   +++++   +  L   K  +          + +K+L +  E   +   AK +E   LV           T     K  ++    Q R  + ++  ++N LE A   D +   + +   + +  KL  +  + + K+++  K   K  +++ ++V E           RL                 KD  + +  L      LKE +AK     TN     P E I++         R +QL++E   LL   + ++   E    + + +K L+ +   + + IK  + S
Sbjct: 1617 QLEDFVKETLRAS-KDIYDKAVKLNETLGIPNKTLDKSFQELQKDIDSMMAELRRKSLRNQKNTADDEL----KAAEALLNRVKKLFLEAHK-KNEDLNNEVKEKLGLFEEKLDDV--WDLLR---EARGKIKAAD-DLSTVNQKNMTELEQGVEKGKKETESVLGDGDSIMTEVNNLAQIINEDLSDMNKELPPLTEQLNEKINNLTQEIARRDLPEQILQAENQAAQLIDSSAVLDGILAEAKNLSFNATVAFNAYSNIKDLIDDAEDTAKEAKAKANEAIDLV----------RTKKSFTKIHMQQNFIQARYNENDLAGIKNRLENA---DEKNQNMLQALNDTF-GKLALIPNDTLVKIQTA-KDKAKQANDTASDVLE-----------RL-----------------KDLNLNLLGLKQNYTALKEDVAK-----TNAAVKDPVENITDADG------RVKQLEKEADRLLDKLKPIKELQENLGKNISQIKELINQARKQANSIKVSVSS 2068
[Close]
BLAST of Fatty acid synthase vs. UniProt/SwissProt
Match: sp|Q21313|EPI1_CAEEL (Laminin-like protein epi-1 OS=Caenorhabditis elegans OX=6239 GN=epi-1 PE=1 SV=1)

HSP 1 Score: 54.299 bits (129), Expect = 5.622e-6
Identity = 88/454 (19.38%), Postives = 177/454 (38.99%), Query Frame = 3 
Query:  465 VVKELERKIIQLESETKEKQYALMADVEETLRSREGELKRKTEQVHTEMLNYELKYRLASKELDLTRISKAEILRNLTEKENRIRELEMKLTEIELANKSEISIEKMKRETEAVHAKENQTNLLKEIENLTRRINEKNNKLKSKIETAKKLENEIKSVLNAARXXXXXXXXXXXXXXXXXXXXXNKMKELANQVEKEKENISAKDSEIARLVSRMTGENLKKETD---------------LRNAKFEIENLVEQLRKKQEEMLELRNELEYAVCKDLEISKIKEGEKENWESKLQRVRIEEMAKVESMIKALTKSRDESIAEVRELRQQLEEKRQVRLCSNCSNESVKNSRINESKDEQIVIKELNSQNAKLKEIIAKMTEETTNQVSNQPPETISNNRHIASLAERNRQLQQEKIDLLATSRKLQARFEATESDNNNMKRLVREKDTEISQIK 1781
            ++KE E  ++ LE+ + ++       V   L   + +++ +TE++  +   +E + + A +EL     S  ++L+    K ++   +   L   ++ N      + ++R  EA   +  + N+   I N+T  + +K  ++   + T  +  N++   L AA++                     +++     V+ +  N  A +  +     R T +N K  TD               L+NAK +I+N  E L              E A  + ++ ++ K    E  E                 I AL+K+  + + E  +L++QLE+  ++        E+VK      SK+    I E   +  KLK  I    EET  ++S    +         S  E  R  ++  + L   +  + ++FE  +  ++     V     ++SQIK
Sbjct: 2277 LLKEAEETLMTLEAASADQYPEKAQTVPGKLEEIQKKIQEETEKLDKQKETFEAQKKRA-EELAAYLNSAQQLLKESKSKADKSNNIAKMLQLTKVENLVAAITDDLER-VEAAKGEFQKLNV--AIGNITENLKDKREEMTHAVTTLNETRNDVAEALEAAKK---------------------RVRRDEKSVDMQLVNAKAHELHLQATTLRQTFDNNKDNTDQAVEAANAFSNLTDTLKNAKAQIDNAYEALSA------------EPAFAESVQNARDKPFPDETKEK----------------IDALSKTVSQDLKETEKLKKQLEQLTELSEKLRKRKEAVKAGIPKYSKNTLDSIDEKVQEVEKLKAEIDANIEETRAKISEIAGKAEEITEKANSAMEGIRLARRNSVQLNKLAPVIVSKFEELKKLSSARSAKVDSVSDKVSQIK 2677
[Close]
BLAST of Fatty acid synthase vs. TrEMBL
Match: A0A267FTY0 (Uncharacterized protein (Fragment) OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig003830g2 PE=4 SV=1)

HSP 1 Score: 172.17 bits (435), Expect = 2.599e-40
Identity = 234/860 (27.21%), Postives = 421/860 (48.95%), Query Frame = 3 
Query:   57 QKEKEWKDLL---LVQLEKSKIERNKAEIALGEFQEKFFQLEIDFKHNLKXXXXXXXXXXXXXXXXXXXXXSVYENEEKISLLSVEVDKLKMELQMSNETKEDLRNKMKQVIDKAFNDSQSLKNEKIKEIQRIKDGNATVVKELERKIIQLESETKEKQYALMADVEETLRSREGELKRKTEQVHTEMLNYELKYRLASKELDLTRISKAEILRNLTEKENRIRELEMKLTEIELANKSEISIEKMKRETEAVHAKENQTNLLKEIENLTRRINEKNNKLKSKIETA-KKLENEIKSVLNAARXXXXXXXXXXXXXXXXXXXXXNKMKELANQVEKEKE-----------NISAKDSEIARL-----------------VSRMTGENLKKETDLRNAKFEIENLVEQLRKKQEEMLELRNELEYAVCKDLEISKIKEGEKENWESKLQRVRIEEMAKVESMIKALTKSRDESIAEVRELRQQLEEK----------RQVRLCSNCSNESVKNSRINESKD---EQIV-----IKELNSQNAKLKEIIAKMTEETTNQVSNQPPETI------------SNNRHIASLAERNRQLQQEKIDLLATSRKLQARFEATESDNNNMKRLVREKDTEISQIKFELDSLQRHTGMDVRTMRRTLQELETELAVSRKEAEEYYKGNLELGRVIEDLQSELTFLKS---------EQIERMPTLNFGAQEMLIEQLKNEISELRRKL----IYTSEDDIRENKTDDKENTFLKKKLKAAANQIKNLASEKQVLIQISNRLRAEL-----------KQAGVKLPICGNNIKSTTEYFTQNEG-----SKNVKRTISDLEDKLSRLEQLQ 2363
            +KE EWK  L   +  LE++   R   E  L + ++K  QL  DFK+NL+L++ERDEE+  +E+ENI L++     E+K+S +SV+ D++  +L   + +K  L  + K   D    + Q +++E   E+ R+KD +  + ++LE + ++ + E + ++  L+  +++       + + + +Q+   +++ E K  L  KE    R ++ ++L  L   E     LE +L E     +S+I++                      +EN   R+ E +  L++K   A  +LE ++ +    A   E       A L+ E +   N+  +L  ++ + +            N+ AKD+EIA+L                 VSR+    + K+ ++   + ++E   E+L  ++ ++   R+EL+ A+ ++ +   ++   + +++ K   +   +  K ES I+ LT++++E++ E+  ++  L +K          R+  L     N  V   R  ES     +Q+      ++EL  QN  LK+I+ +M  E  + +S+QP +               + + +  ++    +L+ EK DLLA  RK QAR    ES     +      DT   Q+++EL +  RH   +   ++R LQELE +L  S++EA+EYYK N+E GR+ E LQ E+  L+S         +Q +R   +NFGAQE+ I+QL++EI+ LR ++    +Y   DD  E   + ++ + L+ KLK AANQIK LA E Q L+ +SNRLRAEL            QA    P  G+   +T ++  +  G      + VK  + D+  KL++LE++Q
Sbjct:    2 EKELEWKAALNQQVALLEETLASR---ESELRDERKKAAQLTEDFKYNLRLVKERDEELATMERENIVLKQQCLALEDKLSAMSVKHDEVAQKLAEESYSKTKLVEQCKSEQDSRERELQFIRHEHELEVSRLKDEHQALRRQLEMENVRCKKELELQKRELLGALDKRAEELRDDYQNRAKQLEKSLMDSEFKCDLLDKEAASLRKARVDLLNRLETCETESAGLEKRLAEAAARYESDIAV----------------------LENEKERLQELSTSLEAKHRAALARLEEKLAAGQAEATRHEQAAAGAAARLKEERQSMRNQTSDLLAKLHEAEASFQRKATEFDTNLRAKDAEIAKLNGQLEDLQSQLHSSKADVSRLF---VDKDAEIDRLRRQLEVNTEELNNRRADIDRYRHELDAALARERDRESMQHQMELDYQRKASELEALQYEKSESYIERLTQAKNEALRELESMQTTLAQKQTFIQSLLKDRETALQVMKENGIVMPDRRLESASVETDQLAASERRVRELVQQNESLKDIVKQMRLEMESLISSQPQQQQQQQQQKKQQLQLGDQKSVQEISNALSKLRSEKTDLLAQCRKQQARIGHLESQLAECQTEREAADTAAEQLRYELSAQARHHSTESAGLKRRLQELEAQLDESQREADEYYKANIEAGRLAERLQQEVLVLRSAAGSAGGEQQQQQRPGEVNFGAQELYIQQLQDEIAGLRDRMRAKQLYG--DDEAEAGNESEQVSRLRAKLKMAANQIKKLAQENQALVDLSNRLRAELNTGNRGQQRPSAQASRYKPSAGS---ATAQHQGEPIGLESHSRRAVKDAVGDMTSKLAQLERMQ 828
[Close]
BLAST of Fatty acid synthase vs. TrEMBL
Match: A0A1S3KEF0 (coiled-coil domain-containing protein 57 OS=Lingula unguis OX=7574 GN=LOC106181124 PE=4 SV=1)

HSP 1 Score: 171.4 bits (433), Expect = 7.309e-40
Identity = 235/904 (26.00%), Postives = 428/904 (47.35%), Query Frame = 3 
Query:   45 DIIFQKEKEWKDLLLVQLEKSKIERNKAEIALGEFQEKFFQLEIDFKHNLKXXXXXXXXXXXXXXXXXXXXXSVYENEEKISLLSVEVDKLKMELQMSNETKEDLRNKMKQVIDKAFNDSQSLKNEKIKEIQRIKDGNATVVKELERKIIQLESETKEKQYALMADVEETLRSREGELKRKTEQVHTEMLNYELKYRLASKELDLTRISKA------------EILRNLTE---------------KENRIRELEMKLTEIELANKSEISIEKMKRETEAVHAKENQTNLLK--EIENLTRRINEKN-NKLKSKIETA----KKLENEIKSVLNAARXXXXXXXXXXXXXXXXXXXXXNKMKELANQVEKEKENISAKDSEIARLVSRMTGENLKKETDLRNAKFEIENLVEQLRKKQEEMLELRNELEYAVCKDLEISKIKEGEKENWESKLQRVRIEEMAKVESMIKALTKSRDESIAEVRELRQQLEEKRQ-VRLCS-------------------NCSNESVKNSRINESKDEQIVIKELNSQNAKLKEIIAKM---------------------TEE------------------------TTNQVSNQPP---------ETISNN----RHIASLAERNRQLQQEKIDLLATSRKLQARFEATESDNNNMKRLVREKDTEISQIKFELDSLQRHTGMDVRTMRRTLQELETELAVSRKEAEEYYKGNLELGRVIEDLQSELTFLKSEQIERMPTLNFGAQEMLIEQLKNEISELRRKLI-----YTSEDDIR---ENKTDDKENTFLKKKLKAAANQIKNLASEKQVLIQISNRLRAELKQAGVK-----------LPICGNNIKSTTEYFTQNEGSKNVKRTISDLEDKLSRLEQLQ 2363
            ++  QKEKEW++L  ++    +I   + E  L +   KF +L+ DFK+NLKLLEERD E+   +     L+ ++     +IS + ++ D+L   L+   + KE L+   +Q + +   +    ++EK  EI+  ++    + + LE ++ ++E E   ++  + A  +E ++ RE E + + ++   ++L YELK +L +KE+++  +S+A            +  R L +               K+ RI+ELE KL + EL  K      + K E    +A+E ++ LLK  E  + T R+ ++N  +L++++E A    ++L+ E + +                      ++ E + ++L  ++   KE   A+ SEIAR        N+ ++ +L+  K   +++  +L++K+E +   + E+  AV ++  + + K     +W+ + + V   +  + E ++K LT++RDE+ A ++E  ++L+++   +R+ +                   N    +V  +      +E   I +L +QN KL+ +I +M                     TEE                        T  Q    PP         ++I +N     HI SL +    L++EK++L A  +K QAR +  E+  N + +  REK  EI Q+++EL +  R    +V ++R+ + ELE +L  +RKEA+EY+K NLE    +  LQ+EL+ LK +  ++ P +N+G QE++I+QL++EI  L+ KL         +  IR   E  T D+    L+ KLK AA  I  LA EKQ LI++ NR RA L   G++           +P+        T   +Q             +++KL+ LEQLQ
Sbjct:   14 ELAAQKEKEWRELQELRNHTLEIAYKEKENQLNQENAKFMKLKEDFKYNLKLLEERDVELERYDAIFGELKAAINAKNGEISEMKIQQDELCASLKREEQAKEQLQMHYQQRMREKQTEVDQFRSEKEAEIKAEREQLENIKRNLEHQLREVEGELDVQKREITAGFDEAMKRREHEFRTQMDEKSGQILAYELKIKLLTKEVEM--LSEAGEKTEKEFHHVDQNHRTLEKKFKEKEWEFNDMQAMKDARIQELESKLHQTELGVKRMEEEFQRKFEERDRYAREKESALLKVKEGHHETERVLQENIRELQTQLEQAQVESRRLQWENQDL---------------------AKEKELQAEKLHGEIHDVKEKWDAQLSEIART-------NVARDLELQALKDNEDSIKAELQQKKESIERYKKEMTLAVEREASLERAKAQLDLDWQRRYEEVERLQYERSEDLVKNLTRARDEAFATLKEKDRELQQRESLIRVLTRDRDQALATLKQHGLVLDRNIDTSAVHGTPTQSESEE---ISQLQAQNEKLRTVIRQMRTEMENIGDQEPVKQKPGNSVTEEYVRMLEDEVRSLKSKMRNAESDLQTKQQPREDPPLAQAQDLLMKSIGDNALVRSHIQSLNDTIASLRREKVELSAQVKKQQARLQFQEASQNKLSKQPREKQLEIDQLQYELGAQGRRHVAEVASLRQKIAELELQLIETRKEADEYFKANLEKNLELNSLQNELSSLKVDLAQKTPGINYGGQELMIQQLEDEIKRLQNKLAGRPDPMIPDQPIRGPAEGATVDQ----LRSKLKQAAKHITQLAKEKQQLIEVGNRQRAILMNHGIRLPTPPRLPPKVMPLPAPAKPVATGRISQA------------VQNKLTELEQLQ 868
[Close]
BLAST of Fatty acid synthase vs. TrEMBL
Match: A0A267GXW9 (Uncharacterized protein (Fragment) OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig003830g1 PE=4 SV=1)

HSP 1 Score: 170.244 bits (430), Expect = 1.216e-39
Identity = 233/857 (27.19%), Postives = 420/857 (49.01%), Query Frame = 3 
Query:   57 QKEKEWKDLL---LVQLEKSKIERNKAEIALGEFQEKFFQLEIDFKHNLKXXXXXXXXXXXXXXXXXXXXXSVYENEEKISLLSVEVDKLKMELQMSNETKEDLRNKMKQVIDKAFNDSQSLKNEKIKEIQRIKDGNATVVKELERKIIQLESETKEKQYALMADVEETLRSREGELKRKTEQVHTEMLNYELKYRLASKELDLTRISKAEILRNLTEKENRIRELEMKLTEIELANKSEISIEKMKRETEAVHAKENQTNLLKEIENLTRRINEKNNKLKSKIETA-KKLENEIKSVLNAARXXXXXXXXXXXXXXXXXXXXXNKMKELANQVEKEKE-----------NISAKDSEIARL-----------------VSRMTGENLKKETDLRNAKFEIENLVEQLRKKQEEMLELRNELEYAVCKDLEISKIKEGEKENWESKLQRVRIEEMAKVESMIKALTKSRDESIAEVRELRQQLEEK----------RQVRLCSNCSNESVKNSRINESKD---EQIV-----IKELNSQNAKLKEIIAKMTEETTNQVSNQPPETI------------SNNRHIASLAERNRQLQQEKIDLLATSRKLQARFEATESDNNNMKRLVREKDTEISQIKFELDSLQRHTGMDVRTMRRTLQELETELAVSRKEAEEYYKGNLELGRVIEDLQSELTFLKS---------EQIERMPTLNFGAQEMLIEQLKNEISELRRKL----IYTSEDDIRENKTDDKENTFLKKKLKAAANQIKNLASEKQVLIQISNRLRAELKQA--GVKLPIC-GNNIKSTTEYFT-QNEGS---------KNVKRTISDLEDKLSRLEQLQ 2363
            +KE EWK  L   +  LE++   R   E  L + ++K  QL  DFK+NL+L++ERDEE+  +E+ENI L++     E+K+S +SV+ D++  +L   + +K  L  + K   D    + Q +++E   E+ R+KD +  + ++LE + ++ + E + ++  L+  +++       + + + +Q+   +++ E K  L  KE    R ++ ++L  L   E     LE +L E     +S+I++                      +EN   R+ E +  L++K   A  +LE ++ +    A   E       A L+ E +   N+  +L  ++ + +            N+ AKD+EI +L                 VSR+    + K+ ++   + ++E   E+L  ++ ++   R+EL+ A+ ++ +   ++   + +++ K   +   +  K ES I+ LT++++E++ E+  ++  L +K          R+  L     N  V   R  ES     +Q+      ++EL  QN  LK+I+ +M  E  + +S+QP +               + + +  ++    +L+ EK DLLA  RK QAR    ES     +      DT   Q+++EL +  RH   +   ++R LQELE +L  S++EA+EYYK N+E GR+ E LQ E+  L+S         +Q +R   +NFGAQE+ I+QL++EI+ LR ++    +Y   DD  E   + ++ + L+ KLK AANQIK LA E Q L+ +SNRLRAEL     G + P    +  K +    T Q++G          + VK  + D+  KL++LE++Q
Sbjct:    2 EKELEWKAALNQQVALLEETLASR---ESELRDERKKAAQLTEDFKYNLRLVKERDEELATMERENIVLKQQCLALEDKLSAMSVKHDEVAQKLAEESYSKTKLVEQCKSEQDSRERELQFIRHENELEVSRLKDEHQALRRQLEMENVRCKKELELQKRELLGALDKRAEELRDDYQNRAKQLEKSLMDSEFKCDLLDKEAASLRKARVDLLNRLETCETESAGLEKRLAEAAARYESDIAV----------------------LENEKERLQELSTSLEAKHRAALARLEEKLAAAQAEATRHEQAAAGAAARLKEERQSMRNQTSDLLAKLHEAEASFQRKATEFDTNLRAKDAEIEKLNGQLEDLQSQLHSSKADVSRLF---VDKDAEIDRLRRQLEVNTEELNNRRADIDRYRHELDAALARERDRESMQHQMELDYQRKASELEALQYEKSESYIERLTQAKNEALRELESMQTTLAQKQTFIQSLLKDRETALQVMKENGIVMPDRRLESASVETDQLAASERRVRELVQQNESLKDIVKQMRLEMESLISSQPQQQQQQQQQKKQQLQLGDQKSVQEISNALSKLRSEKTDLLAQCRKQQARIGHLESQLAECQTEREAADTAAEQLRYELSAQARHHSTESAGLKRRLQELEAQLDESQREADEYYKANIEAGRLAERLQQEVLVLRSAAGSAGGEQQQQQRPGEVNFGAQELYIQQLQDEIAGLRDRMRAKQLYG--DDEAEAGNESEQVSRLRAKLKMAANQIKKLAQENQALVDLSNRLRAELNTGNRGQQRPSAQASRYKPSAGSATAQHQGEPIGLESHSRRAVKDAVGDMTSKLAQLERMQ 828
[Close]
BLAST of Fatty acid synthase vs. TrEMBL
Match: A0A1S3HQW7 (coiled-coil domain-containing protein 57-like OS=Lingula unguis OX=7574 GN=LOC106157351 PE=4 SV=1)

HSP 1 Score: 167.933 bits (424), Expect = 9.201e-39
Identity = 225/848 (26.53%), Postives = 406/848 (47.88%), Query Frame = 3 
Query:   45 DIIFQKEKEWKDLLLVQLEKSKIERNKAEIALGEFQEKFFQLEIDFKHNLKXXXXXXXXXXXXXXXXXXXXXSVYENEEKISLLSVEVDKLKMELQMSNETKEDLRNKMKQVIDKAFNDSQSLKNEKIKEIQRIKDGNATVVKELERKIIQLESETKEKQYALMADVEETLRSREGELKRKTEQVHTEMLNYELKYRLASKELDLTRISKA------------EILRNLTE---------------KENRIRELEMKLTEIELANKSEISIEKMKRETEAVHAKENQTNLLK--EIENLTRRINEKN-NKLKSKIETA----KKLENEIKSVLNAARXXXXXXXXXXXXXXXXXXXXXNKMKELANQVEKEKENISAKDSEIARLVSRMTGENLKKETDLRNAKFEIENLVEQLRKKQEEMLELRNELEYAVCKDLEISKIKEGEKENWESKLQRVRIEEMAKVESMIKALTKSRDESIAEV----RELRQQ------LEEKRQVRLCS----------NCSNESVKNSRINESKDEQIVIKELNSQNAKLKEIIAKM---------------------TEE------------------------TTNQVSNQPP---------ETISNN----RHIASLAERNRQLQQEKIDLLATSRKLQARFEATESDNNNMKRLVREKDTEISQIKFELDSLQRHTGMDVRTMRRTLQELETELAVSRKEAEEYYKGNLELGRVIEDLQSELTFLKSEQIERMPTLNFGAQEMLIEQLKNEISELRRKLIYTSEDDIRE----NKTDDKENTFLKKKLKAAANQIKNLASEKQVLIQISNRLRAELKQAGVKL 2240
            ++  QKEKEW++L  ++    +I   + E  L +   KF +L+ DFK+NLKLLEERD E+   +     L+ ++     +IS + ++ D+L   L+     KE L+   +Q + +   +    ++EK  EI+  ++    + + LE ++ ++E E   ++  + A  +E ++ RE E + + ++   ++L YELK +L +K++++  +S+A            +  R L +               K+ RI+ELE KL + EL  K      + K E    +A+E ++ LLK  E  + T R+ ++N  +L++++E A    ++L+ E + +                      ++ E + ++L  ++   KE   A+ SEIAR        N+ ++ +L+  K   +++  +L++K+E +   + E+  AV ++  + + K     +W+ + + V   +  + E ++K LT++RDE+ A +    REL+Q+      L + R   L +          N    +V  +      +E   I  L +QN KL+ +I +M                     TEE                        T  Q    PP         ++I +N     HI SL +    L++EK++L A  +K QAR +  E+  N + +  REK  EI Q+++EL +  R    +V ++ + + ELE +L  +RKEA+EY+K NLE    +  LQ+EL+ LK +  ++ P +N+G QE++I+QL++EI  L+ KL    +  I +      T+      L+ KLK AA  I  LA EKQ LI++ NR RA L   G++L
Sbjct:   14 ELAAQKEKEWRELQELRNHTLEIAYKEKENQLNQENAKFMKLKEDFKYNLKLLEERDVELERYDAIFGELKAAINAKNGEISEMKIQQDELCASLKREEHAKEQLQMHYQQRMREKQTEVDQFRSEKEAEIKAEREQLENIKRNLEHQLREVEGELDVQKREITAGFDEAMKRREHEFRTQMDEKSGQILAYELKIKLLTKDVEM--LSEAGEKTEKEFHHVDQNHRTLEKKFKEKEWEFNDMQAMKDARIQELESKLHQTELGVKRMEEEFQRKFEERDRYAREKESALLKVKEGHHETERVLQENIRELQTQLEQAQVESRRLQWENQDL---------------------AKEKELQAEKLHGEIHDVKEKWDAQLSEIART-------NVARDLELQALKDNEDSIKAELQQKKESIERYKKEMTLAVEREASLERAKAQLDLDWQRRYEEVERLQYERSEDLVKNLTRARDEAFATLKEKDRELQQRESLIKVLTKDRDQALATLKQHGLVLDRNIDTSAVHGTPTQSESEE---ISRLQAQNEKLRTVIRQMRTEMENIGDQEPVKQKPGSPVTEEYVRMLEDEVRSLKSKMRNAESDLQTKQQPREDPPVAHAQDLLMKSIGDNALVRSHIQSLNDTIASLRREKVELSAQVKKQQARLQFQEASQNKLSKQPREKQLEIDQLQYELGAQGRRHVAEVASLCQKIAELELQLIETRKEADEYFKANLEKNLELNSLQNELSSLKVDLAQKTPGINYGGQELMIQQLEDEIKRLQNKLAGRPDHMIPDQPIRGPTESATVDQLRSKLKQAAKHITQLAKEKQQLIEVGNRQRAILMNHGIRL 828
[Close]
BLAST of Fatty acid synthase vs. TrEMBL
Match: A0A267H7T8 (Uncharacterized protein (Fragment) OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig024236g1 PE=4 SV=1)

HSP 1 Score: 167.162 bits (422), Expect = 1.280e-38
Identity = 232/858 (27.04%), Postives = 419/858 (48.83%), Query Frame = 3 
Query:   57 QKEKEWKDLL---LVQLEKSKIERNKAEIALGEFQEKFFQLEIDFKHNLKXXXXXXXXXXXXXXXXXXXXXSVYENEEKISLLSVEVDKLKMELQMSNETKEDLRNKMKQVIDKAFNDSQSLKNEKIKEIQRIKDGNATVVKELERKIIQLESETKEKQYALMADVEETLRSREGELKRKTEQVHTEMLNYELKYRLASKELDLTRISKAEILRNLTEKENRIRELEMKLTEIELANKSEISIEKMKRETEAVHAKENQTNLLKEIENLTRRINEKNNKLKSKIETA-KKLENEIKSVLNAARXXXXXXXXXXXXXXXXXXXXXNKMKELANQVEKEKE-----------NISAKDSEIARL-----------------VSRMTGENLKKETDLRNAKFEIENLVEQLRKKQEEMLELRNELEYAVCKDLEISKIKEGEKENWESKLQRVRIEEMAKVESMIKALTKSRDESIAEVRELRQQLEEK----------RQVRLCSNCSNESVKNSRINESKD---EQIV-----IKELNSQNAKLKEIIAKMTEETTNQVSNQPPETI--------------SNNRHIASLAERNRQLQQEKIDLLATSRKLQARFEATESDNNNMKRLVREKDTEISQIKFELDSLQRHTGMDVRTMRRTLQELETELAVSRKEAEEYYKGNLELGRVIEDLQSELTFLKS--------EQIERMPTLNFGAQEMLIEQLKNEISELRRKL----IYTSEDDIRENKTDDKENTFLKKKLKAAANQIKNLASEKQVLIQISNRLRAELKQA--GVKLPIC-GNNIKSTTEYFT-QNEGS---------KNVKRTISDLEDKLSRLEQLQ 2363
            +KE EWK  L   +  LE++   R   E  L + ++K  QL  DFK+NL+L++ERDEE+  +E+ENI L++     E+K+S +SV+ D++  +L   + +K  L  + K   D    + Q +++E   E+ R+KD +  + ++LE + ++ + E + ++  L+  +++       + + + +Q+   +++ E K  L  KE    R ++ ++L  L   E     LE +L E     +S+I++                      +EN   R+ E +  L++K   A  +LE ++ +    A   E       A L+ E +   N+  +L  ++ + +            N+ AKD+EI +L                 VSR+    + K+ ++   + ++E   E+L  ++ ++   R+EL+ A+ ++ +   ++   + +++ K   +   +  K ES I+ LT++++E++ E+  ++  L +K          R+  L     N  V   R  ES     +Q+      ++EL  QN  LK+I+ +M  E  + +S+QP +                 + + +  ++    +L+ EK DLLA  RK QAR     S     +      DT   Q+++EL +  RH   +   ++R LQELE +L  S++EA+EYYK N+E GR+ E LQ E+  L+S        +Q +R   +NFGAQE+ I+QL++EI+ LR ++    +Y   DD  E   + ++ + L+ KLK AANQIK LA E Q L+ +SNRLRAEL     G + P    +  K +    T Q++G          + VK  + D+  KL++LE++Q
Sbjct:    2 EKELEWKAALNQQVALLEETLASR---ESELRDERKKAAQLTEDFKYNLRLVKERDEELATMERENIVLKQQCLALEDKLSAMSVKHDEVAQKLAEESYSKTKLVEQCKSEQDSRERELQFIRHENELEVSRLKDEHQALRRQLEMENVRCKKELELQKRELLGALDKRAEELRDDYQNRAKQLEKSLMDSEFKCDLLDKEAASLRKARVDLLNRLETCETESAGLEKRLAEAAARYESDIAV----------------------LENEKERLQELSTSLEAKHRAALARLEEKLAAGQAEATRHEQAAAGAAARLKEERQSMRNQTSDLLAKLHEAEASFQRKATEFDTNLRAKDAEIEKLNGQLEDLQSQLHSSKADVSRLF---VDKDAEIDRLRRQLEVNTEELNNRRADIDRYRHELDAALARERDRESMQHQMELDYQRKASELEALQYEKSESYIERLTQAKNEALRELESMQTTLAQKQTFIQSLLKDRETALQVMKENGIVMPDRRLESASVETDQLAASERRVRELVQQNESLKDIVKQMRLEMESLISSQPQQQQQQQQQQQKKQQLQLGDQKSVQEISNALSKLRSEKTDLLAQCRKQQARIGHLGSQLAECQTEREAADTAAEQLRYELSAQARHHSTESAGLKRRLQELEAQLDESQREADEYYKANIEAGRLAERLQQEVLVLRSAAGSAGGEQQQQRPGEVNFGAQELYIQQLQDEIAGLRDRMRAKQLYG--DDEAEAGNESEQVSRLRAKLKMAANQIKKLAQENQALVDLSNRLRAELNTGNRGQQRPSAQASRYKPSAGSATAQHQGEPIGLESHSRRAVKDAVGDMTSKLAQLERMQ 829
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BLAST of Fatty acid synthase vs. Ensembl Cavefish
Match: CCDC57 (coiled-coil domain containing 57 [Source:HGNC Symbol;Acc:HGNC:27564])

HSP 1 Score: 104.76 bits (260), Expect = 1.715e-22
Identity = 213/861 (24.74%), Postives = 409/861 (47.50%), Query Frame = 3 
Query:   30 LSDNTDIIFQ---KEKEWKDLLLVQLEKSKIERNKAEIALGEFQEKFFQLEIDFKHNLKXXXXXXXXXXXXXXXXXXXXXSVYENEEKISLLSVEVDKLKMELQMSNETKEDLRNKMKQVIDKAFNDSQSLKNEKIKEIQRIKDGNATVVKELERKIIQLESETKEKQYALMADVEETLRSREGELKRKTEQVHTEMLNYELKYRLASKELD------------------LTRISKAEILR-------NLTEKENRIRELEMKLTEIELANK--SEISIEKMKRETEAVHAKENQTNLLKEIENLT-RRINEKNNKLKSKIETAKKLENEIKSVLNAARXXXXXXXXXXXXXXXXXXXXXNKMKELANQVEKEKENISAKDSEIARLVSRMTGENLKKETDL-----RNAKFEIENLVEQLRKKQEEM-LELRNELEYAVCKDLEISKIKEGEKENWESKLQRVRIEEMAKVESMIKALTKSRDESIAEVRELRQQLEEKRQVRLCSNCSNESVKNSRINESKDEQIV----IKELNSQNAKLKEIIAKMTEETTNQVSNQPP-ETISNNRH------IASLAERNRQLQQEKIDLLATSRKLQARF-EATESDN-------------------NNMKRL---VREKDTEIS----------QIKFELDSLQRHTGMDVRTMRRTLQELETELAVSRKEAEEYYKGNLELGRVIEDLQSELTFLKSEQIERMPTLNFGAQEMLIEQLKNEISELRRKLIYTSEDDIRENKTDDKENTFLKKKLKAAANQIKNLASEKQVLIQISNRLRAELKQAGVKL--PICGNNIKSTTEYFTQNEGSKNVKRTISDLEDKLSRLEQLQ 2363
            + D+ D+  Q   KE+EWK+L  +++++ +    +A   L   +E+F QL  DF++NL++LEERD E+   +   + +R       E++S L ++V +L+  +       +DL+ + ++   +     + +++ K  EIQ++++ N  + ++L+R+I + E E   ++  +MAD +  +R RE E   + +++H  +L++ELK +L SKEL+                  L + ++ EIL            K +RI+ELE KL ++E   K  +E++  K          +E     +KE      R   +K   L++++E    LE E +                +   E +L+  + +++EL  Q+EK +    A        +++++ E + K+T+L     R AK   E     L+K +E++    + +L   + ++  + K +   + +WE + + VR E   K E +I+ LT++RD+  AE+RE  ++L E   V L  + + E  K   +   ++        I+ L  QN+ L+E+IA+M  +        PP + ++  +H      I    E ++ L++E  +L A  R+L+ +  E ++++N                   N++K L   + ++  +IS           ++ EL + +R +  +  ++++ +   + +L   ++EAEEY KG+L        L ++++ LK +   R   +     EM ++QL+ E +   R+ +       R +   D     L+ KLK AA+ I  L+ +K+ LI++ NRLRA+L +AGV    PI             + E  K V  T +  + +LS LEQLQ
Sbjct:    1 MQDSGDLEAQLACKEREWKELQALRIQQLETALAEATSQLFSQRERFSQLRDDFQYNLRVLEERDRELEVYDAMAVQVRTEESARHEELSELRIQVARLQETIGEERRQNQDLQAQYQKRGVEHRLQLERIQSVKEDEIQKLREENEALKRDLQRRIQESEGELALQKQEMMADFDSEMRKREHEFNLRLDEMHNVVLSHELKVKLLSKELEVHAQAHSQATEALQMSEELCQQAQKEILNRDWDLKNTAAVKNSRIKELEEKLKQMEAKQKREAEVNNRKHAELERRAREREAALGAMKEAHCCDLREEKKKATVLQTRLERLY-LEQESR----------------EKGHENDLQHRDQQIQELRTQLEKTQAGWDA-------YITQVSKETVAKDTELLSVGEREAKVRAE-----LQKCKEDVESRYKQQLASGIQREQALEKKRVQLELDWERRCEEVRAEHYLKSEELIQGLTQARDQVTAELREKERELLET--VTLLKSVTIERDKALSMAAGEERNSFPSEEIRRLQQQNSSLREVIAEMRRQMETLSKEVPPAQNVTLTQHPDPEPIITGTTEYSQALEEELQNLKAKCRRLEDQLDEVSKTNNPIPTSDQQLPVSPENAYLQNHIKSLNETIGDRKYQISFCHSRQIENEALRVELANHKRESAAEKASLKQKIAAADMQLEEVKREAEEYQKGSLIHNLETVALGNQVSALKLDIASRREPIVLQQSEM-VKQLQEE-NLSLRQQLLLLHCSGRGDVAGDA--NLLQSKLKQAAHWISRLSQDKRQLIEMGNRLRAQLAEAGVATSKPILS---------LQEKESQKAVPETQT--QSRLSTLEQLQ 815
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BLAST of Fatty acid synthase vs. Planmine SMEST
Match: SMESG000020850.1 (SMESG000020850.1)

HSP 1 Score: 1586.62 bits (4107), Expect = 0.000e+0
Identity = 873/879 (99.32%), Postives = 875/879 (99.54%), Query Frame = 3 
Query:   12 MSQHRFLSDNTDIIFQKEKEWKDLLLVQLEKSKIERNKAEIALGEFQEKFFQLEIDFKHNLKXXXXXXXXXXXXXXXXXXXXXSVYENEEKISLLSVEVDKLKMELQMSNETKEDLRNKMKQVIDKAFNDSQSLKNEKIKEIQRIKDGNATVVKELERKIIQLESETKEKQYALMADVEETLRSREGELKRKTEQVHTEMLNYELKYRLASKELDLTRISKAEILRNLTEKENRIRELEMKLTEIELANKSEISIEKMKRETEAVHAKENQTNLLKEIENLTRRINEKNNKLKSKIETAKKLENEIKSVLNAARXXXXXXXXXXXXXXXXXXXXXNKMKELANQVEKEKENISAKDSEIARLVSRMTGENLKKETDLRNAKFEIENLVEQLRKKQEEMLELRNELEYAVCKDLEISKIKEGEKENWESKLQRVRIEEMAKVESMIKALTKSRDESIAEVRELRQQLEEKRQVRLCSNCSNESVKNSRINESKDEQIVIKELNSQNAKLKEIIAKMTEETTNQVSNQPPETISNNRHIASLAERNRQLQQEKIDLLATSRKLQARFEATESDNNNMKRLVREKDTEISQIKFELDSLQRHTGMDVRTMRRTLQELETELAVSRKEAEEYYKGNLELGRVIEDLQSELTFLKSEQIERMPTLNFGAQEMLIEQLKNEISELRRKLIYTSEDDIRENKTDDKENTFLKKKLKAAANQIKNLASEKQVLIQISNRLRAELKQAGVKLPICGNNIKSTTEYFTQNEGSKNVKRTISDLEDKLSRLEQLQKSMRNDCINQDIITKKSSLKSPKDMVSSVGRESVDEVFKXXXXXXXXXXXXXXXNGTNLPMKTFVNGTPSNFLWSKSVKLNSPKSRTKRNMVTNK 2648
            MSQHRFLSDNTDIIFQKEKEWKDLLL QLEKSKIERNKAEIALGEFQEKFFQLEIDFKHNLKLLEERDEEINEIEQENINLRESVYENEEKISLLSVEVDKLK ELQMSNETKEDLRNKMKQVIDKAFNDSQS+KNEKIKEIQRIKDGNATVVKELERKIIQLESETKEKQYALMADVEETLRSREGELKRKTEQVHTEMLNYELKYRLASKELDLTRISKAEILRNLTEKEN IRELEMK TEIELANKSEISIEKMKRETEAVHAKENQTNLLKEIENLTRRINEKN+KLKSKIETAKKLENEIKSVLNAAREKELKIEKEKATLELELEKFENKMKELANQVEKEKENISAKDSEIARLVSRMTGENLKKETDLRNAKFEIENLVEQLRKKQEEMLELRNELEYAVCKDLEISKIKEGEKENWESKLQRVRIEEMAKVESMIKALTKSRDESIAEVRELRQQLEEKRQVRLCSNCSNESVKNSRINESKDEQIVIKELNSQNAKLKEIIAKMTEETTNQVSNQPPETISNNRHIASLAERNRQLQQEKIDLLATSRKLQARFEATESDNNNMKRLVREKDTEISQIKFELDSLQRHTGMDVRTMRRTLQELETELAVSRKEAEEYYKGNLELGRVIEDLQSELTFLKSEQIERMPTLNFGAQEMLIEQLKNEISELRRKLIYTSEDDIRENKTDDKENTFLKKKLKAAANQIKNLASEKQVLIQISNRLRAELKQAGVKLPICGNNIKSTTEYFTQNEGSKNVKRTISDLEDKLSRLEQLQKSMRNDCINQDIITKKSSLKSPKDMVSSVGRESVDEVFKLLDDSDSLGQSSLLDNGTNLPMKTFVNGTPSNFLWSKSVKLNSPKSRTKRNMVTNK
Sbjct:    1 MSQHRFLSDNTDIIFQKEKEWKDLLLEQLEKSKIERNKAEIALGEFQEKFFQLEIDFKHNLKLLEERDEEINEIEQENINLRESVYENEEKISLLSVEVDKLKTELQMSNETKEDLRNKMKQVIDKAFNDSQSMKNEKIKEIQRIKDGNATVVKELERKIIQLESETKEKQYALMADVEETLRSREGELKRKTEQVHTEMLNYELKYRLASKELDLTRISKAEILRNLTEKENTIRELEMKFTEIELANKSEISIEKMKRETEAVHAKENQTNLLKEIENLTRRINEKNDKLKSKIETAKKLENEIKSVLNAAREKELKIEKEKATLELELEKFENKMKELANQVEKEKENISAKDSEIARLVSRMTGENLKKETDLRNAKFEIENLVEQLRKKQEEMLELRNELEYAVCKDLEISKIKEGEKENWESKLQRVRIEEMAKVESMIKALTKSRDESIAEVRELRQQLEEKRQVRLCSNCSNESVKNSRINESKDEQIVIKELNSQNAKLKEIIAKMTEETTNQVSNQPPETISNNRHIASLAERNRQLQQEKIDLLATSRKLQARFEATESDNNNMKRLVREKDTEISQIKFELDSLQRHTGMDVRTMRRTLQELETELAVSRKEAEEYYKGNLELGRVIEDLQSELTFLKSEQIERMPTLNFGAQEMLIEQLKNEISELRRKLIYTSEDDIRENKTDDKENTFLKKKLKAAANQIKNLASEKQVLIQISNRLRAELKQAGVKLPICGNNIKSTTEYFTQNEGSKNVKRTISDLEDKLSRLEQLQKSMRNDCINQDIITKKSSLKSPKDMVSSVGRESVDEVFKLLDDSDSLGQSSLLDNGTNLPMKTFVNGTPSNFLWSKSVKLNSPKSRTKRNMVTNK 879
The following BLAST results are available for this feature:
BLAST of Fatty acid synthase vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Fatty acid synthase vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
epi-14.382e-719.38Laminin-like protein epi-1 [Source:UniProtKB/Swis... [more]
epi-14.384e-719.38Laminin-like protein epi-1 [Source:UniProtKB/Swis... [more]
epi-14.386e-719.38Laminin-like protein epi-1 [Source:UniProtKB/Swis... [more]
epi-14.420e-719.38Laminin-like protein epi-1 [Source:UniProtKB/Swis... [more]
epi-14.420e-719.38Laminin-like protein epi-1 [Source:UniProtKB/Swis... [more]
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BLAST of Fatty acid synthase vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Fatty acid synthase vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 1
Match NameE-valueIdentityDescription
fasn1.258e-925.26fatty acid synthase [Source:ZFIN;Acc:ZDB-GENE-0301... [more]
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BLAST of Fatty acid synthase vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 2
Match NameE-valueIdentityDescription
CCDC574.966e-1724.18coiled-coil domain containing 57 [Source:NCBI gene... [more]
wdcp5.977e-621.43WD repeat and coiled coil containing [Source:Xenba... [more]
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BLAST of Fatty acid synthase vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Fatty acid synthase vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 1
Match NameE-valueIdentityDescription
sp|Q21313|EPI1_CAEEL5.622e-619.38Laminin-like protein epi-1 OS=Caenorhabditis elega... [more]
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BLAST of Fatty acid synthase vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A267FTY02.599e-4027.21Uncharacterized protein (Fragment) OS=Macrostomum ... [more]
A0A1S3KEF07.309e-4026.00coiled-coil domain-containing protein 57 OS=Lingul... [more]
A0A267GXW91.216e-3927.19Uncharacterized protein (Fragment) OS=Macrostomum ... [more]
A0A1S3HQW79.201e-3926.53coiled-coil domain-containing protein 57-like OS=L... [more]
A0A267H7T81.280e-3827.04Uncharacterized protein (Fragment) OS=Macrostomum ... [more]
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BLAST of Fatty acid synthase vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 1
Match NameE-valueIdentityDescription
CCDC571.715e-2224.74coiled-coil domain containing 57 [Source:HGNC Symb... [more]
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BLAST of Fatty acid synthase vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Fatty acid synthase vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Fatty acid synthase vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Fatty acid synthase vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Fatty acid synthase vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 1
Match NameE-valueIdentityDescription
SMESG000020850.10.000e+099.32SMESG000020850.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30008325 ID=SMED30008325|Name=Fatty acid synthase|organism=Schmidtea mediterranea sexual|type=transcript|length=2662bp
ATGATTTTTAAATGTCTCAGCATCGATTTTTATCTGATAATACTGATATA
ATTTTTCAAAAAGAAAAAGAATGGAAAGATCTTTTGTTGGTGCAATTGGA
AAAATCGAAAATAGAACGTAATAAAGCCGAAATTGCTTTGGGAGAATTTC
AAGAAAAATTTTTTCAATTAGAAATAGATTTTAAACATAATTTGAAGCTT
TTAGAAGAACGAGATGAAGAAATAAATGAAATCGAACAAGAAAATATTAA
TTTACGCGAATCGGTTTATGAAAACGAAGAGAAAATCAGTCTTTTAAGCG
TGGAGGTAGATAAATTAAAAATGGAGTTACAAATGTCGAATGAAACGAAA
GAGGATTTAAGGAATAAAATGAAGCAAGTTATTGATAAAGCATTCAATGA
TTCACAATCCTTGAAGAATGAGAAAATTAAAGAAATCCAACGGATAAAAG
ATGGAAACGCCACTGTTGTGAAAGAACTAGAAAGAAAAATAATCCAACTT
GAATCCGAAACCAAAGAAAAGCAATATGCATTAATGGCAGATGTCGAAGA
AACCCTTCGATCAAGAGAAGGAGAATTGAAAAGGAAAACCGAACAAGTCC
ACACGGAAATGCTGAACTATGAACTGAAATACCGATTAGCCAGCAAAGAG
TTGGATTTGACTCGGATAAGTAAAGCGGAGATTCTGAGAAATCTCACCGA
AAAAGAGAACAGAATCCGAGAATTGGAAATGAAATTAACTGAAATCGAGC
TGGCAAACAAAAGTGAAATATCAATCGAAAAAATGAAACGGGAAACCGAA
GCAGTTCACGCAAAAGAAAACCAAACGAACTTATTGAAAGAAATCGAAAA
TCTAACTAGAAGAATCAACGAAAAGAACAATAAATTAAAAAGCAAAATCG
AAACCGCGAAAAAATTGGAAAACGAAATCAAATCCGTTTTAAATGCAGCA
CGGGAAAAGGAGTTGAAAATCGAAAAAGAAAAAGCCACTCTCGAATTGGA
GTTGGAGAAATTCGAAAACAAAATGAAAGAATTAGCAAATCAAGTGGAGA
AAGAAAAAGAAAACATCTCGGCAAAAGATTCGGAAATCGCTCGTTTGGTG
TCGAGAATGACGGGGGAAAATTTGAAAAAAGAAACCGATCTTAGAAATGC
AAAATTCGAAATCGAGAATTTAGTCGAACAGTTGAGAAAGAAACAAGAAG
AAATGTTGGAGTTGAGAAATGAGTTGGAATATGCGGTTTGTAAGGATCTC
GAAATCAGTAAGATAAAGGAAGGCGAAAAGGAGAACTGGGAATCGAAATT
GCAACGGGTTAGAATAGAAGAAATGGCAAAAGTGGAATCAATGATCAAAG
CTCTAACAAAGAGCCGGGATGAAAGTATAGCGGAAGTGCGGGAATTGCGG
CAGCAATTGGAGGAGAAAAGACAAGTTCGACTCTGTTCAAATTGTTCAAA
TGAATCTGTGAAAAATTCAAGAATAAATGAGTCAAAAGACGAGCAAATAG
TGATTAAAGAATTGAATTCTCAAAATGCTAAATTAAAAGAAATAATTGCC
AAGATGACAGAGGAAACTACAAACCAAGTTAGTAATCAGCCACCGGAAAC
GATAAGCAATAATAGGCATATTGCTAGTCTAGCTGAGCGTAACCGTCAAC
TACAACAGGAAAAAATAGACTTACTTGCAACAAGCCGTAAATTACAAGCT
CGTTTCGAAGCTACCGAATCAGACAACAATAACATGAAACGATTAGTTCG
TGAAAAAGACACTGAAATCAGTCAGATAAAATTCGAGCTCGATTCACTTC
AAAGACACACCGGAATGGATGTGCGTACGATGCGTCGAACCTTGCAAGAA
TTGGAAACTGAGTTAGCAGTAAGCCGTAAAGAAGCCGAAGAGTATTATAA
AGGAAATTTAGAGCTTGGTCGGGTCATTGAGGATTTGCAATCGGAATTGA
CATTCTTAAAATCTGAACAAATTGAAAGGATGCCAACATTAAATTTTGGT
GCTCAGGAGATGTTGATTGAACAACTGAAAAACGAAATCAGTGAGTTAAG
AAGAAAATTAATTTATACTTCTGAAGATGACATTCGGGAAAATAAGACAG
ATGATAAAGAAAATACATTCCTCAAAAAAAAACTGAAAGCCGCTGCAAAT
CAAATAAAAAATTTGGCCAGCGAAAAACAGGTATTAATTCAAATCAGTAA
TCGTCTACGCGCCGAATTGAAACAAGCAGGGGTCAAATTACCCATTTGTG
GAAACAATATTAAAAGTACCACTGAGTATTTTACACAAAATGAAGGCAGT
AAAAATGTAAAACGTACGATTAGTGATTTGGAGGATAAACTATCCAGGTT
AGAGCAGCTGCAGAAGAGCATGAGAAATGATTGCATAAATCAAGATATCA
TAACAAAGAAGTCCAGTTTGAAATCACCAAAAGATATGGTGAGTTCAGTT
GGAAGAGAATCTGTAGACGAGGTATTCAAACTGTTGGATGATTCAGATTC
CCTTGGTCAGTCGTCATTGCTAGATAACGGCACCAATTTACCAATGAAAA
CATTTGTCAATGGTACACCAAGCAACTTTCTTTGGTCGAAATCCGTAAAG
TTAAATTCCCCAAAATCCCGAACAAAGCGTAACATGGTTACTAATAAATA
ATTTTCCTTTAC
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protein sequence of SMED30008325-orf-1

>SMED30008325-orf-1 ID=SMED30008325-orf-1|Name=SMED30008325-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=880bp
MSQHRFLSDNTDIIFQKEKEWKDLLLVQLEKSKIERNKAEIALGEFQEKF
FQLEIDFKHNLKLLEERDEEINEIEQENINLRESVYENEEKISLLSVEVD
KLKMELQMSNETKEDLRNKMKQVIDKAFNDSQSLKNEKIKEIQRIKDGNA
TVVKELERKIIQLESETKEKQYALMADVEETLRSREGELKRKTEQVHTEM
LNYELKYRLASKELDLTRISKAEILRNLTEKENRIRELEMKLTEIELANK
SEISIEKMKRETEAVHAKENQTNLLKEIENLTRRINEKNNKLKSKIETAK
KLENEIKSVLNAAREKELKIEKEKATLELELEKFENKMKELANQVEKEKE
NISAKDSEIARLVSRMTGENLKKETDLRNAKFEIENLVEQLRKKQEEMLE
LRNELEYAVCKDLEISKIKEGEKENWESKLQRVRIEEMAKVESMIKALTK
SRDESIAEVRELRQQLEEKRQVRLCSNCSNESVKNSRINESKDEQIVIKE
LNSQNAKLKEIIAKMTEETTNQVSNQPPETISNNRHIASLAERNRQLQQE
KIDLLATSRKLQARFEATESDNNNMKRLVREKDTEISQIKFELDSLQRHT
GMDVRTMRRTLQELETELAVSRKEAEEYYKGNLELGRVIEDLQSELTFLK
SEQIERMPTLNFGAQEMLIEQLKNEISELRRKLIYTSEDDIRENKTDDKE
NTFLKKKLKAAANQIKNLASEKQVLIQISNRLRAELKQAGVKLPICGNNI
KSTTEYFTQNEGSKNVKRTISDLEDKLSRLEQLQKSMRNDCINQDIITKK
SSLKSPKDMVSSVGRESVDEVFKLLDDSDSLGQSSLLDNGTNLPMKTFVN
GTPSNFLWSKSVKLNSPKSRTKRNMVTNK*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: biological process
TermDefinition
GO:0002943tRNA dihydrouridine synthesis
GO:0008033tRNA processing
GO:0055114oxidation-reduction process
Vocabulary: molecular function
TermDefinition
GO:0003824catalytic activity
GO:0016740transferase activity
GO:0017150tRNA dihydrouridine synthase activity
GO:0050660flavin adenine dinucleotide binding
GO:0046872metal ion binding
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000016pharynx
PLANA:0000020protonephridia
PLANA:0000034epidermis
PLANA:0000099neuron
PLANA:0000418head
PLANA:0002089reproductive organ
Vocabulary: INTERPRO
TermDefinition
IPR042481CCDC57
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableCOILSCoilCoilcoord: 221..248
NoneNo IPR availableCOILSCoilCoilcoord: 175..195
NoneNo IPR availableCOILSCoilCoilcoord: 604..631
NoneNo IPR availableCOILSCoilCoilcoord: 445..472
NoneNo IPR availableCOILSCoilCoilcoord: 763..790
NoneNo IPR availableCOILSCoilCoilcoord: 537..564
NoneNo IPR availableCOILSCoilCoilcoord: 99..126
NoneNo IPR availableCOILSCoilCoilcoord: 662..689
NoneNo IPR availableCOILSCoilCoilcoord: 264..358
NoneNo IPR availableCOILSCoilCoilcoord: 498..518
NoneNo IPR availableCOILSCoilCoilcoord: 22..49
NoneNo IPR availableCOILSCoilCoilcoord: 701..728
NoneNo IPR availableCOILSCoilCoilcoord: 370..411
NoneNo IPR availableCOILSCoilCoilcoord: 60..91
NoneNo IPR availableCOILSCoilCoilcoord: 153..173
IPR042481Coiled-coil domain-containing protein 57PANTHERPTHR46725FAMILY NOT NAMEDcoord: 543..787
coord: 13..529