IMD domain-containing protein

Overview


Name	IMD domain-containing protein
Smed ID	SMED30008314
Length (bp)	2693

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of IMD domain-containing protein (SMED30008314) t-SNE clustered cells

Violin plots show distribution of expression levels for IMD domain-containing protein (SMED30008314) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of IMD domain-containing protein (SMED30008314) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for IMD domain-containing protein (SMED30008314) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30008314

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 7

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
nervous system	SMED30008314	SMESG000038660.1	dd_Smed_v4_3500_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
neuron	SMED30008314	SMESG000038660.1	dd_Smed_v4_3500_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
neoblast	SMED30008314	SMESG000038660.1	dd_Smed_v4_3500_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
parenchymal cell	SMED30008314	SMESG000038660.1	dd_Smed_v4_3500_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
muscle cell	SMED30008314	SMESG000038660.1	dd_Smed_v4_3500_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30008314	SMESG000038660.1	Contig47964	uc_Smed_v2	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30008314	SMESG000038660.1	Contig47964	newmark_ests	PMID:29674431 Fincher et al., 2018

Note: Hover over icons to view figure legend

Homology

[Close]

BLAST of IMD domain-containing protein vs. Ensembl Human
Match: MTSS2 (MTSS I-BAR domain containing 2 [Source:HGNC Symbol;Acc:HGNC:25094])

HSP 1 Score: 94.7449 bits (234), Expect = 2.890e-19
Identity = 58/194 (29.90%), Postives = 110/194 (56.70%), Query Frame = 1

Query:   91 VCDIASKSPCCIKNTGISLTKLVLRQKKIEQKVSTLNSYLNENLSSELDKFLVEWRKTSLNLKRERDHDWKKANLEYQKSLAEVERTEKKLRKKNAGKVGLSETASLQIDYANQDAQNKRRYVEELERSAMRRAAIEERQRFKQFLVLLKPILDCQLSMREDLDNLEEVVSQLYGEKSENLDEFPEELEQNIQE 672
            V D+A+ +    ++ G +LT++ +R + IE K+    + L E+L + L + + +W+K +  L ++   ++K+A  E +K  ++  + +KK RK+  GK  L      Q+D A QD  +    +EE E+ A+RRA IEER RF  F+  L+P+++ +L+M  ++ +L+ ++  L    +E   + P   EQ I++
Sbjct:   60 VADMATNTRGATRDIGSALTRMCMRHRSIETKLRQFTNALLESLINPLQERIEDWKKAANQLDKDHAKEYKRARHEIKKKSSDTLKLQKKARKELLGKGDLQP----QLDSALQDVNDMYLLLEETEKQAVRRALIEERGRFCTFITFLQPVVNGELTMLGEITHLQGIIDDLVVLTAEP-HKLPPASEQVIKD 248

[Close]

BLAST of IMD domain-containing protein vs. Ensembl Human
Match: MTSS2 (MTSS I-BAR domain containing 2 [Source:HGNC Symbol;Acc:HGNC:25094])

HSP 1 Score: 90.5077 bits (223), Expect = 6.589e-18
Identity = 57/194 (29.38%), Postives = 109/194 (56.19%), Query Frame = 1

Query:   91 VCDIASKSPCCIKNTGISLTKLVLRQKKIEQKVSTLNSYLNENLSSELDKFLVEWRKTSLNLKRERDHDWKKANLEYQKSLAEVERTEKKLRKKNAGKVGLSETASLQIDYANQDAQNKRRYVEELERSAMRRAAIEERQRFKQFLVLLKPILDCQLSMREDLDNLEEVVSQLYGEKSENLDEFPEELEQNIQE 672
            V D+A+ +    ++ G +LT++ +R + IE K+    + L E+L + L + + +W+K +  L ++   ++K+A  E +K  ++  + +K+ R K  GK  L      Q+D A QD  +    +EE E+ A+RRA IEER RF  F+  L+P+++ +L+M  ++ +L+ ++  L    +E   + P   EQ I++
Sbjct:   60 VADMATNTRGATRDIGSALTRMCMRHRSIETKLRQFTNALLESLINPLQERIEDWKKAANQLDKDHAKEYKRARHEIKKKSSDTLKLQKR-RAKVPGKGDLQP----QLDSALQDVNDMYLLLEETEKQAVRRALIEERGRFCTFITFLQPVVNGELTMLGEITHLQGIIDDLVVLTAEP-HKLPPASEQVIKD 247

[Close]

BLAST of IMD domain-containing protein vs. Ensembl Human
Match: MTSS1 (MTSS I-BAR domain containing 1 [Source:HGNC Symbol;Acc:HGNC:20443])

HSP 1 Score: 88.9669 bits (219), Expect = 2.169e-17
Identity = 60/194 (30.93%), Postives = 108/194 (55.67%), Query Frame = 1

Query:   91 VCDIASKSPCCIKNTGISLTKLVLRQKKIEQKVSTLNSYLNENLSSELDKFLVEWRKTSLNLKRERDHDWKKANLEYQKSLAEVERTEKKLRKKNAGKVGLSETASLQIDYANQDAQNKRRYVEELERSAMRRAAIEERQRFKQFLVLLKPILDCQLSMREDLDNLEEVVSQLYGEKSENLD--EFPEELEQNI 666
            V D+A+ +    +  G +LT++ +R + IE K+   +S L + L + L + + EW+K +  L ++   ++KKA  E +K  ++  + +KK  KK  G +        Q+D A QD  +K   +EE E+ A+R+A IEER RF  F+ +L+P+++ ++SM  ++ +L+ +   L   KS  +D  + P   EQ I
Sbjct:   61 VADMATNTRGGTREIGSALTRMCMRHRSIEAKLRQFSSALIDCLINPLQEQMEEWKKVANQLDKDHAKEYKKARQEIKKKSSDTLKLQKKA-KKGRGDI------QPQLDSALQDVNDKYLLLEETEKQAVRKALIEERGRFCTFISMLRPVIEEEISMLGEITHLQTISEDL---KSLTMDPHKLPSSSEQVI 244

[Close]

BLAST of IMD domain-containing protein vs. Ensembl Human
Match: MTSS1 (MTSS I-BAR domain containing 1 [Source:HGNC Symbol;Acc:HGNC:20443])

HSP 1 Score: 88.1965 bits (217), Expect = 2.959e-17
Identity = 60/194 (30.93%), Postives = 108/194 (55.67%), Query Frame = 1

Query:   91 VCDIASKSPCCIKNTGISLTKLVLRQKKIEQKVSTLNSYLNENLSSELDKFLVEWRKTSLNLKRERDHDWKKANLEYQKSLAEVERTEKKLRKKNAGKVGLSETASLQIDYANQDAQNKRRYVEELERSAMRRAAIEERQRFKQFLVLLKPILDCQLSMREDLDNLEEVVSQLYGEKSENLD--EFPEELEQNI 666
            V D+A+ +    +  G +LT++ +R + IE K+   +S L + L + L + + EW+K +  L ++   ++KKA  E +K  ++  + +KK  KK  G +        Q+D A QD  +K   +EE E+ A+R+A IEER RF  F+ +L+P+++ ++SM  ++ +L+ +   L   KS  +D  + P   EQ I
Sbjct:   61 VADMATNTRGGTREIGSALTRMCMRHRSIEAKLRQFSSALIDCLINPLQEQMEEWKKVANQLDKDHAKEYKKARQEIKKKSSDTLKLQKKA-KKGRGDI------QPQLDSALQDVNDKYLLLEETEKQAVRKALIEERGRFCTFISMLRPVIEEEISMLGEITHLQTISEDL---KSLTMDPHKLPSSSEQVI 244

[Close]

BLAST of IMD domain-containing protein vs. Ensembl Human
Match: MTSS1 (MTSS I-BAR domain containing 1 [Source:HGNC Symbol;Acc:HGNC:20443])

HSP 1 Score: 88.1965 bits (217), Expect = 3.879e-17
Identity = 59/194 (30.41%), Postives = 110/194 (56.70%), Query Frame = 1

Query:   91 VCDIASKSPCCIKNTGISLTKLVLRQKKIEQKVSTLNSYLNENLSSELDKFLVEWRKTSLNLKRERDHDWKKANLEYQKSLAEVERTEKKLRKKNAGKVGLSETASLQIDYANQDAQNKRRYVEELERSAMRRAAIEERQRFKQFLVLLKPILDCQLSMREDLDNLEEVVSQLYGEKSENLD--EFPEELEQNI 666
            V D+A+ +    +  G +LT++ +R + IE K+   +S L + L + L + + EW+K +  L ++   ++KKA  E +K  ++  + +KK +K +   +G  +    Q+D A QD  +K   +EE E+ A+R+A IEER RF  F+ +L+P+++ ++SM  ++ +L+ +   L   KS  +D  + P   EQ I
Sbjct:   61 VADMATNTRGGTREIGSALTRMCMRHRSIEAKLRQFSSALIDCLINPLQEQMEEWKKVANQLDKDHAKEYKKARQEIKKKSSDTLKLQKKAKKVDT--LGRGDIQP-QLDSALQDVNDKYLLLEETEKQAVRKALIEERGRFCTFISMLRPVIEEEISMLGEITHLQTISEDL---KSLTMDPHKLPSSSEQVI 248

[Close]

BLAST of IMD domain-containing protein vs. Ensembl Fly
Match: mim (gene:FBgn0053558 transcript:FBtr0332943)

HSP 1 Score: 80.1073 bits (196), Expect = 7.565e-15
Identity = 45/175 (25.71%), Postives = 93/175 (53.14%), Query Frame = 1

Query:   85 HSVCDIASKSPCCIKNTGISLTKLVLRQKKIEQKVSTLNSYLNENLSSELDKFLVEWRKTSLNLKRERDHDWKKANLEYQKSLAEVERTEKKLRKKNAGKVGLSETASLQIDYANQDAQNKRRYVEELERSAMRRAAIEERQRFKQFLVLLKPILDCQLSMREDLDNLEEVVSQL 609
              + D A+ S    K  G +LT++ LR K +E ++ T  S + + L   L + + +W++T   + ++   ++K+   E +K  ++  R +KK RK      G ++     +D   QD   +R  +EE+E+ ++R A +EER R+  F+ +L+P++  +  +  +L +L+E +  +
Sbjct:   59 QKIADAATNSRGASKEIGTALTRVCLRHKAVETRLKTFTSTIMDCLVQPLQERIEDWKRTVATIDKDHAKEYKRCRSELKKRSSDTLRLQKKARK------GQTDGLQSLMDSHMQDVTLRRAELEEVEKKSLRAAMVEERLRYCSFVHMLQPVVHEECEVMSELGHLQEAMQSI 227

[Close]

BLAST of IMD domain-containing protein vs. Ensembl Fly
Match: mim (gene:FBgn0053558 transcript:FBtr0332944)

HSP 1 Score: 80.1073 bits (196), Expect = 7.817e-15
Identity = 47/172 (27.33%), Postives = 93/172 (54.07%), Query Frame = 1

Query:   91 VCDIASKSPCCIKNTGISLTKLVLRQKKIEQKVSTLNSYLNENLSSELDKFLVEWRKTSLNLKRERDHDWKKANLEYQKSLAEVERTEKKLRKKNAGKVGLSETASLQ--IDYANQDAQNKRRYVEELERSAMRRAAIEERQRFKQFLVLLKPILDCQLSMREDLDNLEEVV 600
            + D A+ S    K  G +LT++ LR K +E ++ T  S + + L   L + + +W++T   + ++   ++K+   E +K  ++  R +KK RK         +T  LQ  +D   QD   +R  +EE+E+ ++R A +EER R+  F+ +L+P++  +  +  +L +L+E +
Sbjct:   61 IADAATNSRGASKEIGTALTRVCLRHKAVETRLKTFTSTIMDCLVQPLQERIEDWKRTVATIDKDHAKEYKRCRSELKKRSSDTLRLQKKARK--------GQTDGLQSLMDSHMQDVTLRRAELEEVEKKSLRAAMVEERLRYCSFVHMLQPVVHEECEVMSELGHLQEAM 224

[Close]

BLAST of IMD domain-containing protein vs. Ensembl Fly
Match: mim (gene:FBgn0053558 transcript:FBtr0302035)

HSP 1 Score: 79.7221 bits (195), Expect = 8.328e-15
Identity = 47/172 (27.33%), Postives = 93/172 (54.07%), Query Frame = 1

Query:   91 VCDIASKSPCCIKNTGISLTKLVLRQKKIEQKVSTLNSYLNENLSSELDKFLVEWRKTSLNLKRERDHDWKKANLEYQKSLAEVERTEKKLRKKNAGKVGLSETASLQ--IDYANQDAQNKRRYVEELERSAMRRAAIEERQRFKQFLVLLKPILDCQLSMREDLDNLEEVV 600
            + D A+ S    K  G +LT++ LR K +E ++ T  S + + L   L + + +W++T   + ++   ++K+   E +K  ++  R +KK RK         +T  LQ  +D   QD   +R  +EE+E+ ++R A +EER R+  F+ +L+P++  +  +  +L +L+E +
Sbjct:   61 IADAATNSRGASKEIGTALTRVCLRHKAVETRLKTFTSTIMDCLVQPLQERIEDWKRTVATIDKDHAKEYKRCRSELKKRSSDTLRLQKKARK--------GQTDGLQSLMDSHMQDVTLRRAELEEVEKKSLRAAMVEERLRYCSFVHMLQPVVHEECEVMSELGHLQEAM 224

[Close]

BLAST of IMD domain-containing protein vs. Ensembl Fly
Match: mim (gene:FBgn0053558 transcript:FBtr0302577)

HSP 1 Score: 79.7221 bits (195), Expect = 9.362e-15
Identity = 47/172 (27.33%), Postives = 93/172 (54.07%), Query Frame = 1

Query:   91 VCDIASKSPCCIKNTGISLTKLVLRQKKIEQKVSTLNSYLNENLSSELDKFLVEWRKTSLNLKRERDHDWKKANLEYQKSLAEVERTEKKLRKKNAGKVGLSETASLQ--IDYANQDAQNKRRYVEELERSAMRRAAIEERQRFKQFLVLLKPILDCQLSMREDLDNLEEVV 600
            + D A+ S    K  G +LT++ LR K +E ++ T  S + + L   L + + +W++T   + ++   ++K+   E +K  ++  R +KK RK         +T  LQ  +D   QD   +R  +EE+E+ ++R A +EER R+  F+ +L+P++  +  +  +L +L+E +
Sbjct:   61 IADAATNSRGASKEIGTALTRVCLRHKAVETRLKTFTSTIMDCLVQPLQERIEDWKRTVATIDKDHAKEYKRCRSELKKRSSDTLRLQKKARK--------GQTDGLQSLMDSHMQDVTLRRAELEEVEKKSLRAAMVEERLRYCSFVHMLQPVVHEECEVMSELGHLQEAM 224

[Close]

BLAST of IMD domain-containing protein vs. Ensembl Fly
Match: mim (gene:FBgn0053558 transcript:FBtr0113470)

HSP 1 Score: 79.7221 bits (195), Expect = 9.544e-15
Identity = 47/172 (27.33%), Postives = 93/172 (54.07%), Query Frame = 1

Query:   91 VCDIASKSPCCIKNTGISLTKLVLRQKKIEQKVSTLNSYLNENLSSELDKFLVEWRKTSLNLKRERDHDWKKANLEYQKSLAEVERTEKKLRKKNAGKVGLSETASLQ--IDYANQDAQNKRRYVEELERSAMRRAAIEERQRFKQFLVLLKPILDCQLSMREDLDNLEEVV 600
            + D A+ S    K  G +LT++ LR K +E ++ T  S + + L   L + + +W++T   + ++   ++K+   E +K  ++  R +KK RK         +T  LQ  +D   QD   +R  +EE+E+ ++R A +EER R+  F+ +L+P++  +  +  +L +L+E +
Sbjct:   61 IADAATNSRGASKEIGTALTRVCLRHKAVETRLKTFTSTIMDCLVQPLQERIEDWKRTVATIDKDHAKEYKRCRSELKKRSSDTLRLQKKARK--------GQTDGLQSLMDSHMQDVTLRRAELEEVEKKSLRAAMVEERLRYCSFVHMLQPVVHEECEVMSELGHLQEAM 224

[Close]

BLAST of IMD domain-containing protein vs. Ensembl Zebrafish
Match: mtss1 (MTSS I-BAR domain containing 1 [Source:ZFIN;Acc:ZDB-GENE-081105-141])

HSP 1 Score: 93.5893 bits (231), Expect = 4.603e-19
Identity = 59/192 (30.73%), Postives = 103/192 (53.65%), Query Frame = 1

Query:   91 VCDIASKSPCCIKNTGISLTKLVLRQKKIEQKVSTLNSYLNENLSSELDKFLVEWRKTSLNLKRERDHDWKKANLEYQKSLAEVERTEKKLRKKNAGKVGLSETASLQIDYANQDAQNKRRYVEELERSAMRRAAIEERQRFKQFLVLLKPILDCQLSMREDLDNLEEVVSQLYGEKSENLDEFPEELEQNI 666
            V DIA+ +    K  G +LT++ +R + IE K+    + L +NL + L+  + EW+K +  L  ++DH       EY+K+ +E+++      K         +   +Q+D A QD   +   +EE E+ A+ RA IEER RF  F+ +LKP+LD ++SM  ++ +L+ ++  L G  + + +  P   EQ I
Sbjct:   61 VADIATGTRGATKEIGSALTRMCMRHRSIENKLKLFTTALMDNLITPLELKIEEWKKVASQL--DKDHAK-----EYKKARSEIKKKSSDTIKLQKKVKKGKDEVRMQLDSALQDVNTRYAVLEETEKRAVCRALIEERGRFCSFVTMLKPVLDEEISMLGEVTHLQTILEDL-GNLTADPNTLPPASEQVI 244

[Close]

BLAST of IMD domain-containing protein vs. Ensembl Zebrafish
Match: mtss1la (MTSS I-BAR domain containing 2a [Source:ZFIN;Acc:ZDB-GENE-030219-89])

HSP 1 Score: 92.0485 bits (227), Expect = 1.269e-18
Identity = 54/192 (28.12%), Postives = 106/192 (55.21%), Query Frame = 1

Query:   91 VCDIASKSPCCIKNTGISLTKLVLRQKKIEQKVSTLNSYLNENLSSELDKFLVEWRKTSLNLKRERDHDWKKANLEYQKSLAEVERTEKKLRKKNAGKVGLSETASLQIDYANQDAQNKRRYVEELERSAMRRAAIEERQRFKQFLVLLKPILDCQLSMREDLDNLEEVVSQLYGEKSENLDEFPEELEQNI 666
            V D+A+ +    ++ G +LT++ +R + IE K+    + L E +   L   + EW+KT+  L ++   ++K++  E +K  ++  + +KK RK+  G+ GL      Q++ A QD  +    +EE E+ A+RRA +EER R+  F+  L+P++  +++M  +  +L+ ++  L    + +  + PE  EQ I
Sbjct:   60 VADMATNTRGATRDIGSALTRMCMRHRSIEAKLRHFTNALMEKMIGPLQDKIEEWKKTAALLDKDHAKEYKRSRQEIKKKSSDTIKLQKKARKELPGRGGLQP----QLNSAMQDVNDMYLLMEETEKQAVRRALLEERGRYCTFISFLQPVVVGEIAMLGEATHLQAIIEDLT-VLTTDPHKLPEASEQVI 246

[Close]

BLAST of IMD domain-containing protein vs. Ensembl Zebrafish
Match: mtss1lb (MTSS I-BAR domain containing 2b [Source:ZFIN;Acc:ZDB-GENE-140718-4])

HSP 1 Score: 90.8929 bits (224), Expect = 3.184e-18
Identity = 50/173 (28.90%), Postives = 100/173 (57.80%), Query Frame = 1

Query:   91 VCDIASKSPCCIKNTGISLTKLVLRQKKIEQKVSTLNSYLNENLSSELDKFLVEWRKTSLNLKRERDHDWKKANLEYQKSLAEVERTEKKLRKKNAGKVGLSETASLQIDYANQDAQNKRRYVEELERSAMRRAAIEERQRFKQFLVLLKPILDCQLSMREDLDNLEEVVSQL 609
            V D+A+ +    ++ G +LT++ +R + IE K+    + L E+L + L   + +W+KT+  L ++   ++K++  E +K  ++  + +KK RK   G+  L      Q+D A QD  +    +EE E+ A+RRA +EER RF  F+  L+P+++ +++M  ++ +L+ ++  L
Sbjct:   65 VADMATNTRGATRDIGSALTRMCMRHRSIEAKLRHFTNALMESLITPLQDRIEDWKKTANQLDKDHAKEYKRSRHEIKKKSSDTMKLQKKARK---GRGDLQP----QLDSAMQDVNDMYLLMEETEKQAVRRALVEERGRFCTFISFLQPVVNGEIAMLGEITHLQAIIDDL 230

[Close]

BLAST of IMD domain-containing protein vs. Ensembl Zebrafish
Match: mtss1la (MTSS I-BAR domain containing 2a [Source:ZFIN;Acc:ZDB-GENE-030219-89])

HSP 1 Score: 88.9669 bits (219), Expect = 1.440e-17
Identity = 54/192 (28.12%), Postives = 105/192 (54.69%), Query Frame = 1

Query:   91 VCDIASKSPCCIKNTGISLTKLVLRQKKIEQKVSTLNSYLNENLSSELDKFLVEWRKTSLNLKRERDHDWKKANLEYQKSLAEVERTEKKLRKKNAGKVGLSETASLQIDYANQDAQNKRRYVEELERSAMRRAAIEERQRFKQFLVLLKPILDCQLSMREDLDNLEEVVSQLYGEKSENLDEFPEELEQNI 666
            V D+A+ +    ++ G +LT++ +R + IE K+    + L E +   L   + EW+KT+  L ++   ++K++  E +K  ++  + +KK RK   G+ GL      Q++ A QD  +    +EE E+ A+RRA +EER R+  F+  L+P++  +++M  +  +L+ ++  L    + +  + PE  EQ I
Sbjct:  108 VADMATNTRGATRDIGSALTRMCMRHRSIEAKLRHFTNALMEKMIGPLQDKIEEWKKTAALLDKDHAKEYKRSRQEIKKKSSDTIKLQKKARK---GRGGLQP----QLNSAMQDVNDMYLLMEETEKQAVRRALLEERGRYCTFISFLQPVVVGEIAMLGEATHLQAIIEDLT-VLTTDPHKLPEASEQVI 291

[Close]

BLAST of IMD domain-containing protein vs. Ensembl Xenopus
Match: acss2.2 (acyl-CoA synthetase short-chain family member 2, gene 2 [Source:Xenbase;Acc:XB-GENE-5916994])

HSP 1 Score: 100.138 bits (248), Expect = 4.993e-21
Identity = 55/173 (31.79%), Postives = 103/173 (59.54%), Query Frame = 1

Query:   91 VCDIASKSPCCIKNTGISLTKLVLRQKKIEQKVSTLNSYLNENLSSELDKFLVEWRKTSLNLKRERDHDWKKANLEYQKSLAEVERTEKKLRKKNAGKVGLSETASLQIDYANQDAQNKRRYVEELERSAMRRAAIEERQRFKQFLVLLKPILDCQLSMREDLDNLEEVVSQL 609
            V D+A+ +    ++ G +LT++ +R + IE K+    + L E+L + L + + +W+KT+  L +E   ++K+A  E +K  ++  + +KK RK+  GK  L      Q+D+A QD  +    +EE E+ A+RRA IEER RF  F+ LL+P+++ ++ M  ++ +L+ ++  L
Sbjct:   60 VADMATNTRGATRDIGSALTRMCMRHRSIESKLRHFTNALMESLINPLQERIEDWKKTANTLDKEHAREYKRARHEIKKKSSDTLKLQKKARKEVLGKGDLQP----QLDHALQDVNDMYLLLEETEKQAVRRALIEERGRFCSFITLLQPVVNGEIHMLAEVTHLQAIIEDL 228

[Close]

BLAST of IMD domain-containing protein vs. Ensembl Xenopus
Match: acss2.2 (acyl-CoA synthetase short-chain family member 2, gene 2 [Source:Xenbase;Acc:XB-GENE-5916994])

HSP 1 Score: 99.7525 bits (247), Expect = 6.812e-21
Identity = 55/173 (31.79%), Postives = 103/173 (59.54%), Query Frame = 1

Query:   91 VCDIASKSPCCIKNTGISLTKLVLRQKKIEQKVSTLNSYLNENLSSELDKFLVEWRKTSLNLKRERDHDWKKANLEYQKSLAEVERTEKKLRKKNAGKVGLSETASLQIDYANQDAQNKRRYVEELERSAMRRAAIEERQRFKQFLVLLKPILDCQLSMREDLDNLEEVVSQL 609
            V D+A+ +    ++ G +LT++ +R + IE K+    + L E+L + L + + +W+KT+  L +E   ++K+A  E +K  ++  + +KK RK+  GK  L      Q+D+A QD  +    +EE E+ A+RRA IEER RF  F+ LL+P+++ ++ M  ++ +L+ ++  L
Sbjct:   60 VADMATNTRGATRDIGSALTRMCMRHRSIESKLRHFTNALMESLINPLQERIEDWKKTANTLDKEHAREYKRARHEIKKKSSDTLKLQKKARKEVLGKGDLQP----QLDHALQDVNDMYLLLEETEKQAVRRALIEERGRFCSFITLLQPVVNGEIHMLAEVTHLQAIIEDL 228

[Close]

BLAST of IMD domain-containing protein vs. Ensembl Xenopus
Match: acss2.2 (acyl-CoA synthetase short-chain family member 2, gene 2 [Source:Xenbase;Acc:XB-GENE-5916994])

HSP 1 Score: 96.6709 bits (239), Expect = 7.413e-20
Identity = 55/173 (31.79%), Postives = 102/173 (58.96%), Query Frame = 1

Query:   91 VCDIASKSPCCIKNTGISLTKLVLRQKKIEQKVSTLNSYLNENLSSELDKFLVEWRKTSLNLKRERDHDWKKANLEYQKSLAEVERTEKKLRKKNAGKVGLSETASLQIDYANQDAQNKRRYVEELERSAMRRAAIEERQRFKQFLVLLKPILDCQLSMREDLDNLEEVVSQL 609
            V D+A+ +    ++ G +LT++ +R + IE K+    + L E+L + L + + +W+KT+  L +E   ++K+A  E +K  ++  + +KK RK   GK  L      Q+D+A QD  +    +EE E+ A+RRA IEER RF  F+ LL+P+++ ++ M  ++ +L+ ++  L
Sbjct:   60 VADMATNTRGATRDIGSALTRMCMRHRSIESKLRHFTNALMESLINPLQERIEDWKKTANTLDKEHAREYKRARHEIKKKSSDTLKLQKKARK---GKGDLQP----QLDHALQDVNDMYLLLEETEKQAVRRALIEERGRFCSFITLLQPVVNGEIHMLAEVTHLQAIIEDL 225

[Close]

BLAST of IMD domain-containing protein vs. Ensembl Xenopus
Match: acss2.2 (acyl-CoA synthetase short-chain family member 2, gene 2 [Source:Xenbase;Acc:XB-GENE-5916994])

HSP 1 Score: 96.6709 bits (239), Expect = 8.394e-20
Identity = 55/173 (31.79%), Postives = 102/173 (58.96%), Query Frame = 1

Query:   91 VCDIASKSPCCIKNTGISLTKLVLRQKKIEQKVSTLNSYLNENLSSELDKFLVEWRKTSLNLKRERDHDWKKANLEYQKSLAEVERTEKKLRKKNAGKVGLSETASLQIDYANQDAQNKRRYVEELERSAMRRAAIEERQRFKQFLVLLKPILDCQLSMREDLDNLEEVVSQL 609
            V D+A+ +    ++ G +LT++ +R + IE K+    + L E+L + L + + +W+KT+  L +E   ++K+A  E +K  ++  + +KK RK   GK  L      Q+D+A QD  +    +EE E+ A+RRA IEER RF  F+ LL+P+++ ++ M  ++ +L+ ++  L
Sbjct:   79 VADMATNTRGATRDIGSALTRMCMRHRSIESKLRHFTNALMESLINPLQERIEDWKKTANTLDKEHAREYKRARHEIKKKSSDTLKLQKKARK---GKGDLQP----QLDHALQDVNDMYLLLEETEKQAVRRALIEERGRFCSFITLLQPVVNGEIHMLAEVTHLQAIIEDL 244

[Close]

BLAST of IMD domain-containing protein vs. Ensembl Xenopus
Match: gphn (gephyrin [Source:Xenbase;Acc:XB-GENE-989642])

HSP 1 Score: 89.3521 bits (220), Expect = 9.027e-18
Identity = 50/160 (31.25%), Postives = 93/160 (58.13%), Query Frame = 1

Query:  118 CCIKNTGISLTKLVLRQKKIEQKVSTLNSYLNENLSSELDKFLVEWRKTSLNLKRERDHDWKKANLEYQKSLAEVERTEKKLRKKNAGKVGLSETASLQIDYANQDAQNKRRYVEELERSAMRRAAIEERQRFKQFLVLLKPILDCQLSMREDLDNLEEV 597
            C  +  G +LT++ +R + IE K+   +S L + L + L + + EW+K +  L ++   ++KKA  E +K  ++  + +KK  KK  G +        Q+D A QD  +K   +EE E+ A+R+A IEER RF  F+ +L+P+++ ++SM  ++ +L+ +
Sbjct:   12 CATREVGSALTRMCMRHRSIESKLRQFSSALIDCLINPLQEQMEEWKKVANQLDKDHAKEYKKARQEIKKKSSDTLKLQKKA-KKGRGDI------QPQLDSAMQDVNDKYLLLEETEKQAVRKALIEERSRFCSFISMLRPVIEEEISMLGEITHLQTI 164

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BLAST of IMD domain-containing protein vs. Ensembl Mouse
Match: Mtss2 (MTSS I-BAR domain containing 2 [Source:MGI Symbol;Acc:MGI:3039591])

HSP 1 Score: 91.2781 bits (225), Expect = 2.665e-18
Identity = 53/173 (30.64%), Postives = 101/173 (58.38%), Query Frame = 1

Query:   91 VCDIASKSPCCIKNTGISLTKLVLRQKKIEQKVSTLNSYLNENLSSELDKFLVEWRKTSLNLKRERDHDWKKANLEYQKSLAEVERTEKKLRKKNAGKVGLSETASLQIDYANQDAQNKRRYVEELERSAMRRAAIEERQRFKQFLVLLKPILDCQLSMREDLDNLEEVVSQL 609
            V D+A+ +    ++ G +LT++ +R + IE K+    + L E+L + L + + +W+K++  L ++   ++K+A  E +K  ++  + +KK RK   GK  L      Q+D A QD  +    +EE E+ A+RRA IEER RF  F+  L+P+++ +L+M  ++ +L+ ++  L
Sbjct:   60 VADMATNTRGATRDIGSALTRMCMRHRSIETKLRQFTNALLESLINPLQERIEDWKKSANQLDKDHAKEYKRARHEIKKKSSDTLKLQKKARK---GKGDLQP----QLDSALQDVNDMYLLLEETEKQAVRRALIEERGRFCTFITFLQPVVNGELTMLGEITHLQGIIDDL 225

[Close]

BLAST of IMD domain-containing protein vs. Ensembl Mouse
Match: Mtss1 (MTSS I-BAR domain containing 1 [Source:MGI Symbol;Acc:MGI:2384818])

HSP 1 Score: 90.1225 bits (222), Expect = 6.064e-18
Identity = 60/194 (30.93%), Postives = 110/194 (56.70%), Query Frame = 1

Query:   91 VCDIASKSPCCIKNTGISLTKLVLRQKKIEQKVSTLNSYLNENLSSELDKFLVEWRKTSLNLKRERDHDWKKANLEYQKSLAEVERTEKKLRKKNAGKVGLSETASLQIDYANQDAQNKRRYVEELERSAMRRAAIEERQRFKQFLVLLKPILDCQLSMREDLDNLEEVVSQLYGEKSENLD--EFPEELEQNI 666
            V D+A+ +    +  G +LT++ +R + IE K+   +S L + L + L + + EW+K +  L ++   ++KKA  E +K  ++  + +KK +K +A   G  +    Q+D A QD  +K   +EE E+ A+R+A IEER RF  F+ +L+P+++ ++SM  ++ +L+ +   L   KS  +D  + P   EQ I
Sbjct:   61 VADMATNTRGGTREIGSALTRMCMRHRSIEAKLRQFSSALIDCLINPLQEQMEEWKKVANQLDKDHAKEYKKARQEIKKKSSDTLKLQKKAKKVDAQGRGDIQP---QLDSALQDVNDKYLLLEETEKQAVRKALIEERGRFCTFISMLRPVIEEEISMLGEITHLQTISEDL---KSLTMDPHKLPSSSEQVI 248

[Close]

BLAST of IMD domain-containing protein vs. Ensembl Mouse
Match: Mtss2 (MTSS I-BAR domain containing 2 [Source:MGI Symbol;Acc:MGI:3039591])

HSP 1 Score: 87.0409 bits (214), Expect = 5.265e-17
Identity = 51/170 (30.00%), Postives = 99/170 (58.24%), Query Frame = 1

Query:  100 IASKSPCCIKNTGISLTKLVLRQKKIEQKVSTLNSYLNENLSSELDKFLVEWRKTSLNLKRERDHDWKKANLEYQKSLAEVERTEKKLRKKNAGKVGLSETASLQIDYANQDAQNKRRYVEELERSAMRRAAIEERQRFKQFLVLLKPILDCQLSMREDLDNLEEVVSQL 609
            +A+ +    ++ G +LT++ +R + IE K+    + L E+L + L + + +W+K++  L ++   ++K+A  E +K  ++  + +KK RK   GK  L      Q+D A QD  +    +EE E+ A+RRA IEER RF  F+  L+P+++ +L+M  ++ +L+ ++  L
Sbjct:    1 MATNTRGATRDIGSALTRMCMRHRSIETKLRQFTNALLESLINPLQERIEDWKKSANQLDKDHAKEYKRARHEIKKKSSDTLKLQKKARK---GKGDLQP----QLDSALQDVNDMYLLLEETEKQAVRRALIEERGRFCTFITFLQPVVNGELTMLGEITHLQGIIDDL 163

[Close]

BLAST of IMD domain-containing protein vs. Ensembl Mouse
Match: Mtss2 (MTSS I-BAR domain containing 2 [Source:MGI Symbol;Acc:MGI:3039591])

HSP 1 Score: 67.781 bits (164), Expect = 1.032e-11
Identity = 39/120 (32.50%), Postives = 71/120 (59.17%), Query Frame = 1

Query:  250 EWRKTSLNLKRERDHDWKKANLEYQKSLAEVERTEKKLRKKNAGKVGLSETASLQIDYANQDAQNKRRYVEELERSAMRRAAIEERQRFKQFLVLLKPILDCQLSMREDLDNLEEVVSQL 609
            +W+K++  L ++   ++K+A  E +K  ++  + +KK RK   GK  L      Q+D A QD  +    +EE E+ A+RRA IEER RF  F+  L+P+++ +L+M  ++ +L+ ++  L
Sbjct:    3 DWKKSANQLDKDHAKEYKRARHEIKKKSSDTLKLQKKARK---GKGDLQP----QLDSALQDVNDMYLLLEETEKQAVRRALIEERGRFCTFITFLQPVVNGELTMLGEITHLQGIIDDL 115

[Close]

BLAST of IMD domain-containing protein vs. Ensembl Mouse
Match: Mtss2 (MTSS I-BAR domain containing 2 [Source:MGI Symbol;Acc:MGI:3039591])

HSP 1 Score: 63.1586 bits (152), Expect = 6.783e-10
Identity = 38/111 (34.23%), Postives = 66/111 (59.46%), Query Frame = 1

Query:  283 ERDH--DWKKANLEYQKSLAEVERTEKKLRKKNAGKVGLSETASLQIDYANQDAQNKRRYVEELERSAMRRAAIEERQRFKQFLVLLKPILDCQLSMREDLDNLEEVVSQL 609
            ++DH  ++K+A  E +K  ++  + +KK RK   GK  L      Q+D A QD  +    +EE E+ A+RRA IEER RF  F+  L+P+++ +L+M  ++ +L+ ++  L
Sbjct:    8 DKDHAKEYKRARHEIKKKSSDTLKLQKKARK---GKGDLQP----QLDSALQDVNDMYLLLEETEKQAVRRALIEERGRFCTFITFLQPVVNGELTMLGEITHLQGIIDDL 111

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BLAST of IMD domain-containing protein vs. UniProt/SwissProt
Match: sp|Q765P7|MTSS2_HUMAN (Protein MTSS 2 OS=Homo sapiens OX=9606 GN=MTSS2 PE=1 SV=1)

HSP 1 Score: 94.7449 bits (234), Expect = 1.388e-18
Identity = 58/194 (29.90%), Postives = 110/194 (56.70%), Query Frame = 1

Query:   91 VCDIASKSPCCIKNTGISLTKLVLRQKKIEQKVSTLNSYLNENLSSELDKFLVEWRKTSLNLKRERDHDWKKANLEYQKSLAEVERTEKKLRKKNAGKVGLSETASLQIDYANQDAQNKRRYVEELERSAMRRAAIEERQRFKQFLVLLKPILDCQLSMREDLDNLEEVVSQLYGEKSENLDEFPEELEQNIQE 672
            V D+A+ +    ++ G +LT++ +R + IE K+    + L E+L + L + + +W+K +  L ++   ++K+A  E +K  ++  + +KK RK+  GK  L      Q+D A QD  +    +EE E+ A+RRA IEER RF  F+  L+P+++ +L+M  ++ +L+ ++  L    +E   + P   EQ I++
Sbjct:   60 VADMATNTRGATRDIGSALTRMCMRHRSIETKLRQFTNALLESLINPLQERIEDWKKAANQLDKDHAKEYKRARHEIKKKSSDTLKLQKKARKELLGKGDLQP----QLDSALQDVNDMYLLLEETEKQAVRRALIEERGRFCTFITFLQPVVNGELTMLGEITHLQGIIDDLVVLTAEP-HKLPPASEQVIKD 248

[Close]

BLAST of IMD domain-containing protein vs. UniProt/SwissProt
Match: sp|Q6P9S0|MTSS2_MOUSE (Protein MTSS 2 OS=Mus musculus OX=10090 GN=Mtss2 PE=1 SV=1)

HSP 1 Score: 91.2781 bits (225), Expect = 1.864e-17
Identity = 53/173 (30.64%), Postives = 101/173 (58.38%), Query Frame = 1

Query:   91 VCDIASKSPCCIKNTGISLTKLVLRQKKIEQKVSTLNSYLNENLSSELDKFLVEWRKTSLNLKRERDHDWKKANLEYQKSLAEVERTEKKLRKKNAGKVGLSETASLQIDYANQDAQNKRRYVEELERSAMRRAAIEERQRFKQFLVLLKPILDCQLSMREDLDNLEEVVSQL 609
            V D+A+ +    ++ G +LT++ +R + IE K+    + L E+L + L + + +W+K++  L ++   ++K+A  E +K  ++  + +KK RK   GK  L      Q+D A QD  +    +EE E+ A+RRA IEER RF  F+  L+P+++ +L+M  ++ +L+ ++  L
Sbjct:   60 VADMATNTRGATRDIGSALTRMCMRHRSIETKLRQFTNALLESLINPLQERIEDWKKSANQLDKDHAKEYKRARHEIKKKSSDTLKLQKKARK---GKGDLQP----QLDSALQDVNDMYLLLEETEKQAVRRALIEERGRFCTFITFLQPVVNGELTMLGEITHLQGIIDDL 225

[Close]

BLAST of IMD domain-containing protein vs. UniProt/SwissProt
Match: sp|O43312|MTSS1_HUMAN (Protein MTSS 1 OS=Homo sapiens OX=9606 GN=MTSS1 PE=1 SV=2)

HSP 1 Score: 88.9669 bits (219), Expect = 1.041e-16
Identity = 60/194 (30.93%), Postives = 108/194 (55.67%), Query Frame = 1

Query:   91 VCDIASKSPCCIKNTGISLTKLVLRQKKIEQKVSTLNSYLNENLSSELDKFLVEWRKTSLNLKRERDHDWKKANLEYQKSLAEVERTEKKLRKKNAGKVGLSETASLQIDYANQDAQNKRRYVEELERSAMRRAAIEERQRFKQFLVLLKPILDCQLSMREDLDNLEEVVSQLYGEKSENLD--EFPEELEQNI 666
            V D+A+ +    +  G +LT++ +R + IE K+   +S L + L + L + + EW+K +  L ++   ++KKA  E +K  ++  + +KK  KK  G +        Q+D A QD  +K   +EE E+ A+R+A IEER RF  F+ +L+P+++ ++SM  ++ +L+ +   L   KS  +D  + P   EQ I
Sbjct:   61 VADMATNTRGGTREIGSALTRMCMRHRSIEAKLRQFSSALIDCLINPLQEQMEEWKKVANQLDKDHAKEYKKARQEIKKKSSDTLKLQKKA-KKGRGDI------QPQLDSALQDVNDKYLLLEETEKQAVRKALIEERGRFCTFISMLRPVIEEEISMLGEITHLQTISEDL---KSLTMDPHKLPSSSEQVI 244

[Close]

BLAST of IMD domain-containing protein vs. UniProt/SwissProt
Match: sp|Q8R1S4|MTSS1_MOUSE (Protein MTSS 1 OS=Mus musculus OX=10090 GN=Mtss1 PE=1 SV=1)

HSP 1 Score: 87.8113 bits (216), Expect = 2.065e-16
Identity = 59/194 (30.41%), Postives = 109/194 (56.19%), Query Frame = 1

Query:   91 VCDIASKSPCCIKNTGISLTKLVLRQKKIEQKVSTLNSYLNENLSSELDKFLVEWRKTSLNLKRERDHDWKKANLEYQKSLAEVERTEKKLRKKNAGKVGLSETASLQIDYANQDAQNKRRYVEELERSAMRRAAIEERQRFKQFLVLLKPILDCQLSMREDLDNLEEVVSQLYGEKSENLD--EFPEELEQNI 666
            V D+A+ +    +  G +LT++ +R + IE K+   +S L + L + L + + EW+K +  L ++   ++KKA  E +   ++  + +KK +K +A   G  +    Q+D A QD  +K   +EE E+ A+R+A IEER RF  F+ +L+P+++ ++SM  ++ +L+ +   L   KS  +D  + P   EQ I
Sbjct:   61 VADMATNTRGGTREIGSALTRMCMRHRSIEAKLRQFSSALIDCLINPLQEQMEEWKKVANQLDKDHAKEYKKARQEIKNKSSDTLKLQKKAKKVDAQGRGDIQP---QLDSALQDVNDKYLLLEETEKQAVRKALIEERGRFCTFISMLRPVIEEEISMLGEITHLQTISEDL---KSLTMDPHKLPSSSEQVI 248

[Close]

BLAST of IMD domain-containing protein vs. TrEMBL
Match: A0A1Y1KH05 (IMD domain-containing protein OS=Photinus pyralis OX=7054 PE=4 SV=1)

HSP 1 Score: 113.235 bits (282), Expect = 9.950e-22
Identity = 63/173 (36.42%), Postives = 101/173 (58.38%), Query Frame = 1

Query:   91 VCDIASKSPCCIKNTGISLTKLVLRQKKIEQKVSTLNSYLNENLSSELDKFLVEWRKTSLNLKRERDHDWKKANLEYQKSLAEVERTEKKLRKKNAGKVGLSETASLQIDYANQDAQNKRRYVEELERSAMRRAAIEERQRFKQFLVLLKPILDCQLSMREDLDNLEEVVSQL 609
            + D A+ +    K  G +LT++ LR K +E ++ T  S + + L   L + L +W+KT LNL +E   D+K+A  E +K   +  R +KK+RK   G +        +I+   QD   KR+ +EE E+ A+R A +EER RF  F+  LKP++D +++M  +L +L+EVVSQL
Sbjct:   61 IADSATNARGATKEIGTALTRICLRHKAVETRLKTFTSAVMDCLVVPLQEKLEDWKKTVLNLDKEHAKDYKRARSELKKRSTDTLRLQKKVRKGAGGDL------HKRIECGLQDVSEKRQLLEETEKRAVRAALVEERSRFCTFVGFLKPVVDEEVAMLTELSHLQEVVSQL 227

[Close]

BLAST of IMD domain-containing protein vs. TrEMBL
Match: A0A1Y1KHF1 (IMD domain-containing protein OS=Photinus pyralis OX=7054 PE=4 SV=1)

HSP 1 Score: 113.235 bits (282), Expect = 1.083e-21
Identity = 68/192 (35.42%), Postives = 107/192 (55.73%), Query Frame = 1

Query:   91 VCDIASKSPCCIKNTGISLTKLVLRQKKIEQKVSTLNSYLNENLSSELDKFLVEWRKTSLNLKRERDHDWKKANLEYQKSLAEVERTEKKLRKKNAGKVGLSETASLQIDYANQDAQNKRRYVEELERSAMRRAAIEERQRFKQFLVLLKPILDCQLSMREDLDNLEEVVSQLYGEKSENLDEFPEELEQNI 666
            + D A+ +    K  G +LT++ LR K +E ++ T  S + + L   L + L +W+KT LNL +E   D+K+A  E +K   +  R +KK+RK   G +        +I+   QD   KR+ +EE E+ A+R A +EER RF  F+  LKP++D +++M  +L +L+EVVSQL    S+     P   EQ I
Sbjct:   61 IADSATNARGATKEIGTALTRICLRHKAVETRLKTFTSAVMDCLVVPLQEKLEDWKKTVLNLDKEHAKDYKRARSELKKRSTDTLRLQKKVRKGAGGDL------HKRIECGLQDVSEKRQLLEETEKRAVRAALVEERSRFCTFVGFLKPVVDEEVAMLTELSHLQEVVSQLEKNTSDP-QSLPPASEQVI 245

[Close]

BLAST of IMD domain-containing protein vs. TrEMBL
Match: A0A5N4B4P3 (Uncharacterized protein OS=Photinus pyralis OX=7054 GN=PPYR_01532 PE=4 SV=1)

HSP 1 Score: 112.849 bits (281), Expect = 1.133e-21
Identity = 68/192 (35.42%), Postives = 107/192 (55.73%), Query Frame = 1

Query:   91 VCDIASKSPCCIKNTGISLTKLVLRQKKIEQKVSTLNSYLNENLSSELDKFLVEWRKTSLNLKRERDHDWKKANLEYQKSLAEVERTEKKLRKKNAGKVGLSETASLQIDYANQDAQNKRRYVEELERSAMRRAAIEERQRFKQFLVLLKPILDCQLSMREDLDNLEEVVSQLYGEKSENLDEFPEELEQNI 666
            + D A+ +    K  G +LT++ LR K +E ++ T  S + + L   L + L +W+KT LNL +E   D+K+A  E +K   +  R +KK+RK   G +        +I+   QD   KR+ +EE E+ A+R A +EER RF  F+  LKP++D +++M  +L +L+EVVSQL    S+     P   EQ I
Sbjct:   18 IADSATNARGATKEIGTALTRICLRHKAVETRLKTFTSAVMDCLVVPLQEKLEDWKKTVLNLDKEHAKDYKRARSELKKRSTDTLRLQKKVRKGAGGDL------HKRIECGLQDVSEKRQLLEETEKRAVRAALVEERSRFCTFVGFLKPVVDEEVAMLTELSHLQEVVSQLEKNTSDP-QSLPPASEQVI 202

[Close]

BLAST of IMD domain-containing protein vs. TrEMBL
Match: U4U350 (IMD domain-containing protein OS=Dendroctonus ponderosae OX=77166 GN=D910_02449 PE=4 SV=1)

HSP 1 Score: 109.768 bits (273), Expect = 1.130e-20
Identity = 65/186 (34.95%), Postives = 101/186 (54.30%), Query Frame = 1

Query:  109 KSPCCIKNTGISLTKLVLRQKKIEQKVSTLNSYLNENLSSELDKFLVEWRKTSLNLKRERDHDWKKANLEYQKSLAEVERTEKKLRKKNAGKVGLSETASLQIDYANQDAQNKRRYVEELERSAMRRAAIEERQRFKQFLVLLKPILDCQLSMREDLDNLEEVVSQLYGEKSENLDEFPEELEQNI 666
            ++P   +  G +LT++ LR K +E ++      + E L   L   L EWRKT LNL +E   D+K+A  E +K   +  R +KK+RK   G V        + +   QD   +R+ +EE E+ A+R A IEER RF  F+ LLKP++D +++M  ++ +L+E V QL    S+  +  P   EQ I
Sbjct:   38 QAPRATREIGTALTRICLRHKAVENRMKHFTGVIMECLIIPLQDRLEEWRKTVLNLDKEHARDYKRARTELKKRSTDTLRLQKKMRKGAGGDV------QKRFECGLQDVTERRQLLEETEKHAVRAALIEERGRFCTFVGLLKPVVDEEVAMLTEMGHLQEAVQQLEKHTSDP-NTLPPASEQVI 216

[Close]

BLAST of IMD domain-containing protein vs. TrEMBL
Match: A0A2R2MT41 (MTSS1-like protein OS=Lingula unguis OX=7574 GN=LOC106152420 PE=4 SV=1)

HSP 1 Score: 108.612 bits (270), Expect = 2.863e-20
Identity = 63/182 (34.62%), Postives = 109/182 (59.89%), Query Frame = 1

Query:  121 CIKNTGISLTKLVLRQKKIEQKVSTLNSYLNENLSSELDKFLVEWRKTSLNLKRERDHDWKKANLEYQKSLAEVERTEKKLRKKNAGKVGLSETASLQIDYANQDAQNKRRYVEELERSAMRRAAIEERQRFKQFLVLLKPILDCQLSMREDLDNLEEVVSQLYGEKSENLDEFPEELEQNI 666
              ++ G +LT+L LR K IE K+ +  S L + + + L + + +W+KT  +L +E   ++K+A  E +K+ ++  R +KK RK   GK  +      ++D A QD  +K   +EE E+ A+R A IEER RF QFL  LKP++D ++SM  ++ +L+E++  LY ++ ++ ++ P   EQ I
Sbjct:    7 ATRDIGSALTRLCLRHKSIENKLKSFTSCLMDGMVTPLQEKMEDWKKTVAHLDKEHAKEYKRARQEIKKASSDTIRLQKKARK---GKCDIQ----TRLDNAMQDVNDKYLLLEETEKQAVRNALIEERSRFCQFLGCLKPVVDEEISMLTEVTHLQEILDILY-QQCQDPNQLPASSEQVI 180

[Close]

BLAST of IMD domain-containing protein vs. Ensembl Cavefish
Match: mtss1 (MTSS I-BAR domain containing 1 [Source:ZFIN;Acc:ZDB-GENE-081105-141])

HSP 1 Score: 98.9821 bits (245), Expect = 6.803e-21
Identity = 61/192 (31.77%), Postives = 106/192 (55.21%), Query Frame = 1

Query:   91 VCDIASKSPCCIKNTGISLTKLVLRQKKIEQKVSTLNSYLNENLSSELDKFLVEWRKTSLNLKRERDHDWKKANLEYQKSLAEVERTEKKLRKKNAGKVGLSETASLQIDYANQDAQNKRRYVEELERSAMRRAAIEERQRFKQFLVLLKPILDCQLSMREDLDNLEEVVSQLYGEKSENLDEFPEELEQNI 666
            V DIA+ +    K  G +LT++ +R + IE K+    + L +NL   L+  + EW+K S  L ++   ++KKA  + +K  ++  R +KK++K   GK    +   +Q+D A QD   +   +EE E+ A+ RA +EER RF  F+ +LKP+LD ++ M  ++ +L+ ++  L    +E  +  P   EQ I
Sbjct:   61 VADIATGTRGATKEIGSALTRMCMRHRSIESKLKLFTAALMDNLIGPLELKIEEWKKVSGQLDKDHAKEYKKARADIKKKSSDTIRLQKKVKK---GK----DEVRMQLDSALQDVNIRYAELEETEKRAVCRALVEERGRFCSFVTMLKPVLDEEIGMLGEVTHLQSILEDLCSLTAEP-NTLPPASEQVI 244

[Close]

BLAST of IMD domain-containing protein vs. Ensembl Cavefish
Match: mtss1 (MTSS I-BAR domain containing 1 [Source:ZFIN;Acc:ZDB-GENE-081105-141])

HSP 1 Score: 98.2117 bits (243), Expect = 1.594e-20
Identity = 61/192 (31.77%), Postives = 106/192 (55.21%), Query Frame = 1

Query:   91 VCDIASKSPCCIKNTGISLTKLVLRQKKIEQKVSTLNSYLNENLSSELDKFLVEWRKTSLNLKRERDHDWKKANLEYQKSLAEVERTEKKLRKKNAGKVGLSETASLQIDYANQDAQNKRRYVEELERSAMRRAAIEERQRFKQFLVLLKPILDCQLSMREDLDNLEEVVSQLYGEKSENLDEFPEELEQNI 666
            V DIA+ +    K  G +LT++ +R + IE K+    + L +NL   L+  + EW+K S  L ++   ++KKA  + +K  ++  R +KK++K   GK    +   +Q+D A QD   +   +EE E+ A+ RA +EER RF  F+ +LKP+LD ++ M  ++ +L+ ++  L    +E  +  P   EQ I
Sbjct:   61 VADIATGTRGATKEIGSALTRMCMRHRSIESKLKLFTAALMDNLIGPLELKIEEWKKVSGQLDKDHAKEYKKARADIKKKSSDTIRLQKKVKK---GK----DEVRMQLDSALQDVNIRYAELEETEKRAVCRALVEERGRFCSFVTMLKPVLDEEIGMLGEVTHLQSILEDLCSLTAEP-NTLPPASEQVI 244

[Close]

BLAST of IMD domain-containing protein vs. Ensembl Cavefish
Match: mtss1 (MTSS I-BAR domain containing 1 [Source:ZFIN;Acc:ZDB-GENE-081105-141])

HSP 1 Score: 98.2117 bits (243), Expect = 1.863e-20
Identity = 61/192 (31.77%), Postives = 106/192 (55.21%), Query Frame = 1

Query:   91 VCDIASKSPCCIKNTGISLTKLVLRQKKIEQKVSTLNSYLNENLSSELDKFLVEWRKTSLNLKRERDHDWKKANLEYQKSLAEVERTEKKLRKKNAGKVGLSETASLQIDYANQDAQNKRRYVEELERSAMRRAAIEERQRFKQFLVLLKPILDCQLSMREDLDNLEEVVSQLYGEKSENLDEFPEELEQNI 666
            V DIA+ +    K  G +LT++ +R + IE K+    + L +NL   L+  + EW+K S  L ++   ++KKA  + +K  ++  R +KK++K   GK    +   +Q+D A QD   +   +EE E+ A+ RA +EER RF  F+ +LKP+LD ++ M  ++ +L+ ++  L    +E  +  P   EQ I
Sbjct:   61 VADIATGTRGATKEIGSALTRMCMRHRSIESKLKLFTAALMDNLIGPLELKIEEWKKVSGQLDKDHAKEYKKARADIKKKSSDTIRLQKKVKK---GK----DEVRMQLDSALQDVNIRYAELEETEKRAVCRALVEERGRFCSFVTMLKPVLDEEIGMLGEVTHLQSILEDLCSLTAEP-NTLPPASEQVI 244

[Close]

BLAST of IMD domain-containing protein vs. Ensembl Cavefish
Match: mtss1la (MTSS1-like protein [Source:NCBI gene;Acc:103039604])

HSP 1 Score: 93.5893 bits (231), Expect = 3.796e-19
Identity = 56/192 (29.17%), Postives = 108/192 (56.25%), Query Frame = 1

Query:   91 VCDIASKSPCCIKNTGISLTKLVLRQKKIEQKVSTLNSYLNENLSSELDKFLVEWRKTSLNLKRERDHDWKKANLEYQKSLAEVERTEKKLRKKNAGKVGLSETASLQIDYANQDAQNKRRYVEELERSAMRRAAIEERQRFKQFLVLLKPILDCQLSMREDLDNLEEVVSQLYGEKSENLDEFPEELEQNI 666
            V D+A+ +    ++ G +LT++ +R + IE K+    + L E L + L   + EW+KT+  L ++   ++K++  E +K  ++  + +KK RK   G+ GL      Q+D A QD  +    +EE E+ A+RRA +EER R+  F+  L+P+++ +++M  ++ +L+ ++  L    + +  + PE  EQ I
Sbjct:   60 VADMATNTRGATRDIGSALTRMCMRHRSIEAKLRHFTNALMERLITPLQDKIEEWKKTAGLLDKDHAKEYKRSRQEIKKKSSDTLKLQKKARK---GRGGLQP----QLDSAMQDVSDMYLLMEETEKQAVRRALLEERGRYCTFISFLQPVVNGEIAMLGEVTHLQAIIDDLT-VLTTDPHKLPEASEQVI 243

[Close]

BLAST of IMD domain-containing protein vs. Ensembl Cavefish
Match: mtss1la (MTSS1-like protein [Source:NCBI gene;Acc:103039604])

HSP 1 Score: 93.5893 bits (231), Expect = 4.176e-19
Identity = 56/192 (29.17%), Postives = 108/192 (56.25%), Query Frame = 1

Query:   91 VCDIASKSPCCIKNTGISLTKLVLRQKKIEQKVSTLNSYLNENLSSELDKFLVEWRKTSLNLKRERDHDWKKANLEYQKSLAEVERTEKKLRKKNAGKVGLSETASLQIDYANQDAQNKRRYVEELERSAMRRAAIEERQRFKQFLVLLKPILDCQLSMREDLDNLEEVVSQLYGEKSENLDEFPEELEQNI 666
            V D+A+ +    ++ G +LT++ +R + IE K+    + L E L + L   + EW+KT+  L ++   ++K++  E +K  ++  + +KK RK   G+ GL      Q+D A QD  +    +EE E+ A+RRA +EER R+  F+  L+P+++ +++M  ++ +L+ ++  L    + +  + PE  EQ I
Sbjct:   60 VADMATNTRGATRDIGSALTRMCMRHRSIEAKLRHFTNALMERLITPLQDKIEEWKKTAGLLDKDHAKEYKRSRQEIKKKSSDTLKLQKKARK---GRGGLQP----QLDSAMQDVSDMYLLMEETEKQAVRRALLEERGRYCTFISFLQPVVNGEIAMLGEVTHLQAIIDDLT-VLTTDPHKLPEASEQVI 243

[Close]

BLAST of IMD domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001774.1 (pep scaffold:Pmarinus_7.0:GL476804:163249:239367:-1 gene:ENSPMAG00000001586.1 transcript:ENSPMAT00000001774.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 95.1301 bits (235), Expect = 2.845e-20
Identity = 65/220 (29.55%), Postives = 119/220 (54.09%), Query Frame = 1

Query:    7 FHNSINLINFE*RLMTXXXXXXXXXXHSVCDIASKSPCCIKNTGISLTKLVLRQKKIEQKVSTLNSYLNENLSSELDKFLVEWRKTSLNLKRERDHDWKKANLEYQKSLAEVERTEKKLRKKNAGKVGLSETASLQIDYANQDAQNKRRYVEELERSAMRRAAIEERQRFKQFLVLLKPILDCQLSMREDLDNLEEVVSQLYGEKSENLDEFPEELEQNI 666
            F N    +N + R  T++    LD+   V D+A+ +    +  G +LT++ +R + IE K+  +++ L E+L S L + + +W++++  L ++   ++K+   E +K  ++  + +KK+RK     V        Q++ A QD  +    +EE E+ A+RRA IEER RF  F+  L+P+LD ++SM E++ +L+ +V  L    S+     P   EQ I
Sbjct:   33 FVNKATKLNSQLRTTTVAVVAFLDAFQKVADMATNTRGSTREIGSALTRVCIRHRSIESKLRQVSTALMESLVSPLQEKIEDWKRSANQLDKDHAKEYKRVRQEIKKKSSDTLKLQKKVRKGKGVDV------QPQLELALQDVNDSYLLLEETEKGAVRRALIEERGRFCTFVYHLRPVLDQEISMLEEVTHLQTIVQDLTNMTSDP-HRLPPASEQVI 245

[Close]

BLAST of IMD domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002039.1 (pep scaffold:Pmarinus_7.0:GL477038:84867:99356:-1 gene:ENSPMAG00000001830.1 transcript:ENSPMAT00000002039.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 65.0846 bits (157), Expect = 4.331e-11
Identity = 40/134 (29.85%), Postives = 71/134 (52.99%), Query Frame = 1

Query:  208 LNENLSSELDKFLVEWRKTSLNLKRERDHDWKKANLEYQKSLAEVERTEKKLRKKNAGKVGLSETASLQIDYANQDAQNKRRYVEELERSAMRRAAIEERQRFKQFLVLLKPILDCQLSMREDLDNLEEVVSQL 609
            L  NL   L + L EW+KT+  L ++   ++KKA  E +K   +  R +KK +K N             +D A Q+  +    ++E E+ A+RRA +EER R+  F  +L+ +L  +++M  D+ +L+ ++  L
Sbjct:    2 LASNLLGPLQEKLEEWKKTAAQLDKDHAKEYKKARQEIKKKSTDTIRLQKKAKKGN-------REVQPALDSALQEVTDTYLLLQEEEKQAVRRALLEERSRYCTFTYMLRDVLTHEVAMLGDVTHLQAILDDL 128

[Close]

BLAST of IMD domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002029.1 (pep scaffold:Pmarinus_7.0:GL477038:82432:99356:-1 gene:ENSPMAG00000001830.1 transcript:ENSPMAT00000002029.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 64.6994 bits (156), Expect = 6.566e-11
Identity = 40/134 (29.85%), Postives = 73/134 (54.48%), Query Frame = 1

Query:  208 LNENLSSELDKFLVEWRKTSLNLKRERDHDWKKANLEYQKSLAEVERTEKKLRKKNAGKVGLSETASLQIDYANQDAQNKRRYVEELERSAMRRAAIEERQRFKQFLVLLKPILDCQLSMREDLDNLEEVVSQL 609
            L  NL   L + L EW+KT+  L ++   ++KKA  E +K   +  R +KK +K+  G   +       +D A Q+  +    ++E E+ A+RRA +EER R+  F  +L+ +L  +++M  D+ +L+ ++  L
Sbjct:    2 LASNLLGPLQEKLEEWKKTAAQLDKDHAKEYKKARQEIKKKSTDTIRLQKKAKKEIIGNREVQPA----LDSALQEVTDTYLLLQEEEKQAVRRALLEERSRYCTFTYMLRDVLTHEVAMLGDVTHLQAILDDL 131

[Close]

BLAST of IMD domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002035.1 (pep scaffold:Pmarinus_7.0:GL477038:82432:99356:-1 gene:ENSPMAG00000001830.1 transcript:ENSPMAT00000002035.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 64.3142 bits (155), Expect = 6.964e-11
Identity = 40/134 (29.85%), Postives = 71/134 (52.99%), Query Frame = 1

Query:  208 LNENLSSELDKFLVEWRKTSLNLKRERDHDWKKANLEYQKSLAEVERTEKKLRKKNAGKVGLSETASLQIDYANQDAQNKRRYVEELERSAMRRAAIEERQRFKQFLVLLKPILDCQLSMREDLDNLEEVVSQL 609
            L  NL   L + L EW+KT+  L ++   ++KKA  E +K   +  R +KK +K N             +D A Q+  +    ++E E+ A+RRA +EER R+  F  +L+ +L  +++M  D+ +L+ ++  L
Sbjct:    2 LASNLLGPLQEKLEEWKKTAAQLDKDHAKEYKKARQEIKKKSTDTIRLQKKAKKGN-------REVQPALDSALQEVTDTYLLLQEEEKQAVRRALLEERSRYCTFTYMLRDVLTHEVAMLGDVTHLQAILDDL 128

[Close]

BLAST of IMD domain-containing protein vs. Ensembl Medaka
Match: mtss1la (MTSS1-like protein [Source:NCBI gene;Acc:101164641])

HSP 1 Score: 93.2041 bits (230), Expect = 5.321e-19
Identity = 57/194 (29.38%), Postives = 110/194 (56.70%), Query Frame = 1

Query:   91 VCDIASKSPCCIKNTGISLTKLVLRQKKIEQKVSTLNSYLNENLSSELDKFLVEWRKTSLNLKRERDHDWKKANLEYQKSLAEVERTEKKLRKKNAGKVGLSETASLQIDYANQDAQNKRRYVEELERSAMRRAAIEERQRFKQFLVLLKPILDCQLSMREDLDNLEEVVSQLYGEKSENLDEFPEELEQNIQE 672
            V D+A+ S    ++ G +LT++ +R + IE K+   ++ L E L + L   + EW+KT+  L ++   ++K++  E ++   +  + +KK RK   G+  L      Q+D A QD  +    +EE E+ A+RRA +EER R+  F+ LL+P+++ +++M  ++ +L+ +V  L    +E+  + P   EQ I++
Sbjct:   60 VADMATNSRGATRDIGSALTRMCMRHRSIEAKLRHFSNVLMEGLVTPLQDRIEEWKKTANQLDKDHTKEYKRSRQEIKRKSLDTIKLQKKARK---GRGNLRP----QLDSAMQDVNDLYLLMEETEKQAVRRALLEERGRYCSFISLLQPVVNVEIAMLGEITHLQAIVEDLT-VLTEDPHKLPPASEQVIRD 245

[Close]

BLAST of IMD domain-containing protein vs. Ensembl Medaka
Match: mtss1la (MTSS1-like protein [Source:NCBI gene;Acc:101164641])

HSP 1 Score: 92.8189 bits (229), Expect = 6.523e-19
Identity = 57/194 (29.38%), Postives = 110/194 (56.70%), Query Frame = 1

Query:   91 VCDIASKSPCCIKNTGISLTKLVLRQKKIEQKVSTLNSYLNENLSSELDKFLVEWRKTSLNLKRERDHDWKKANLEYQKSLAEVERTEKKLRKKNAGKVGLSETASLQIDYANQDAQNKRRYVEELERSAMRRAAIEERQRFKQFLVLLKPILDCQLSMREDLDNLEEVVSQLYGEKSENLDEFPEELEQNIQE 672
            V D+A+ S    ++ G +LT++ +R + IE K+   ++ L E L + L   + EW+KT+  L ++   ++K++  E ++   +  + +KK RK   G+  L      Q+D A QD  +    +EE E+ A+RRA +EER R+  F+ LL+P+++ +++M  ++ +L+ +V  L    +E+  + P   EQ I++
Sbjct:   60 VADMATNSRGATRDIGSALTRMCMRHRSIEAKLRHFSNVLMEGLVTPLQDRIEEWKKTANQLDKDHTKEYKRSRQEIKRKSLDTIKLQKKARK---GRGNLRP----QLDSAMQDVNDLYLLMEETEKQAVRRALLEERGRYCSFISLLQPVVNVEIAMLGEITHLQAIVEDLT-VLTEDPHKLPPASEQVIRD 245

[Close]

BLAST of IMD domain-containing protein vs. Ensembl Medaka
Match: mtss1la (MTSS1-like protein [Source:NCBI gene;Acc:101164641])

HSP 1 Score: 92.8189 bits (229), Expect = 7.581e-19
Identity = 57/194 (29.38%), Postives = 110/194 (56.70%), Query Frame = 1

Query:   91 VCDIASKSPCCIKNTGISLTKLVLRQKKIEQKVSTLNSYLNENLSSELDKFLVEWRKTSLNLKRERDHDWKKANLEYQKSLAEVERTEKKLRKKNAGKVGLSETASLQIDYANQDAQNKRRYVEELERSAMRRAAIEERQRFKQFLVLLKPILDCQLSMREDLDNLEEVVSQLYGEKSENLDEFPEELEQNIQE 672
            V D+A+ S    ++ G +LT++ +R + IE K+   ++ L E L + L   + EW+KT+  L ++   ++K++  E ++   +  + +KK RK   G+  L      Q+D A QD  +    +EE E+ A+RRA +EER R+  F+ LL+P+++ +++M  ++ +L+ +V  L    +E+  + P   EQ I++
Sbjct:   70 VADMATNSRGATRDIGSALTRMCMRHRSIEAKLRHFSNVLMEGLVTPLQDRIEEWKKTANQLDKDHTKEYKRSRQEIKRKSLDTIKLQKKARK---GRGNLRP----QLDSAMQDVNDLYLLMEETEKQAVRRALLEERGRYCSFISLLQPVVNVEIAMLGEITHLQAIVEDLT-VLTEDPHKLPPASEQVIRD 255

[Close]

BLAST of IMD domain-containing protein vs. Ensembl Medaka
Match: MTSS1 (metastasis suppressor protein 1 [Source:NCBI gene;Acc:101157392])

HSP 1 Score: 92.4337 bits (228), Expect = 1.088e-18
Identity = 65/218 (29.82%), Postives = 113/218 (51.83%), Query Frame = 1

Query:   91 VCDIASKSPCCIKNTGISLTKLVLRQKKIEQKVSTLNSYLNENLSSELDKFLVEWRKTSLNLKRERDHDWKKANLEYQKSLAEVERTEKKLRKKNAGKVGLSETASLQIDYANQDAQNKRRYVEELERSAMRRAAIEERQRFKQFLVLLKPILDCQLSMREDLDNLEEVVSQLYGEKSENLDEFPEELEQNIQEHTIDNRSTTC--IPRSYSTLSKQK 738
            V D+A+ S    ++ G +LT++ +R + IE K+   +    E L + L + + EW++    L ++   ++KKA  E +K  ++  + +KK  KK  G +        Q++ A QD  +K   +EE E+ A+R+A IEERQRF  F+ +L+P++D + SM  +L +L+ +   L    S+   + P   EQ I +    +    C   P S ST   +K
Sbjct:   61 VADLATNSRGGTRDIGSALTRMCMRHRSIEAKLKQFSMCFLEGLINPLQEQMEEWKRGVNTLDKDHAKEYKKARQEIKKKSSDTLKLQKKA-KKGRGDI------QPQLNSAMQDVSDKYILLEETEKQALRKALIEERQRFCCFVAMLRPVVDEETSMLGELTHLQTISEDLKALTSDP-HKLPPACEQVITDLKASDYGWLCHTPPSSPSTTMSRK 270

[Close]

BLAST of IMD domain-containing protein vs. Ensembl Medaka
Match: ENSORLT00000000819.2 (MTSS I-BAR domain containing 1 [Source:NCBI gene;Acc:101170030])

HSP 1 Score: 91.2781 bits (225), Expect = 2.059e-18
Identity = 57/204 (27.94%), Postives = 114/204 (55.88%), Query Frame = 1

Query:   91 VCDIASKSPCCIKNTGISLTKLVLRQKKIEQKVSTLNSYLNENLSSELDKFLVEWRKTSLNLKRERDHDWKKANLEYQKSLAEVERTEKKLRKKNAGKVGLSETASLQIDYANQDAQNKRRYVEELERSAMRRAAIEERQRFKQFLVLLKPILDCQLSMREDLDNLEEVVSQLYGEKSENLDEFPEELEQNIQEHTIDNRSTTC 702
            V D+A+ S    ++ G +LT++ +R + IE K+   +    + L + L + + EWR+ +  L ++   ++KKA  E +K  ++  + +KK +K   G+  L      Q+D A QD  ++   +EE E+ A+R+A +EER RF  F+ +L+P++D ++SM  ++ +L+ +   L   K+  +D  P +L  + ++  +D + + C
Sbjct:   61 VADLATNSRGGTRDIGSALTRMCMRHRSIEAKLRQFSMVFLDCLINPLQEQMEEWRRAANALDKDHAKEYKKARQEIKKRSSDTLKLQKKAKK---GRGDLQP----QLDSAMQDVSDRYLLLEETEKQAVRKALVEERSRFCCFVSMLRPVVDEEMSMLGEITHLQTLTDDL---KALTMD--PHKLPPSSEQVIVDMKGSEC 252

[Close]

BLAST of IMD domain-containing protein vs. Planmine SMEST
Match: SMESG000038660.1 (SMESG000038660.1)

HSP 1 Score: 1497.64 bits (3876), Expect = 0.000e+0
Identity = 828/836 (99.04%), Postives = 829/836 (99.16%), Query Frame = 1

Query:    1 LKFHNSINLINFE*RLMTXXXXXXXXXXHSVCDIASKSPCCIKNTGISLTKLVLRQKKIEQKVSTLNSYLNENLSSELDKFLVEWRKTSLNLKRERDHDWKKANLEYQKSLAEVERTEKKLRKKNAGKVGLSETASLQIDYANQDAQNKRRYVEELERSAMRRAAIEERQRFKQFLVLLKPILDCQLSMREDLDNLEEVVSQLYGEKSENLDEFPEELEQNIQEHTIDNRSTTCIPRSYSTLSKQKXXXXXXXXXXXXXXXXXXXXXXXXXXXLITACMEMSSRLNENMSNLSHDSGIKSDKSLSTICDNNSNHDENVNYNWDRTLSNILIESANNESQQQNXXXXXXXXXXXXXXASTDHNSQDGVIDNANDVFPLPEQQTQDNEVHFELPLDYQDNXXXXXXXXXXXXXXXXMQATASHYQQPITIPNDNLYPNQSIPPPVYSNLQELKLNAAKKFGANTLSRISIKDRGNLIQAFNEYPESNIEESSTSFLGNSDKDKPTIPKIPTSQTKATAGKIQEAFHRSQSSVPVSVNDENPPSFNYYNDPESSVNATKIPLKGDSTIKPSMIRRGSFTTEMQVPQTPKNFNTVRKSSTQERTPLNMYSNKNRGRSMSVTREIENDHESPEKSSEDFNAIREILKRQRIVNRINGEATKPVTLPKPELPKKQSPSSNYMAYEYSNTLSSPVALRSNRFFNDRMLRQTNPNAPSGQNIQQMKYQQSRIPSDRDHDIDSAAGEEPACNDFNMSTGPEPIPSMHIERKDDKFKHQLIQMLHSSKSQEAARVAQIPASQHASNISSFYHGXXXXXXXXXXXXXXXXXQKSRTKSTIPNSKYCY 2508
            LKFHNSI       +LMTLSSSDLLDSLHSVCDIASKSPCCIKNTGISLTKLVLRQKKIEQKVSTLNSYLNENLSSELDKFLVEWRKTSLNLKRERDHDWKKANLEYQKSLAEVERTEKKLRKKNAGKVGLSETASLQIDYANQDAQNKRRYVEELERSAMRRAAIEERQRFKQFLVLLKPILDCQLSMREDLDNLEEVVSQLYGEKSENLDEFPEELEQNIQEHTIDNRSTTCIPRSYSTLSKQKSTASTGSHSSLNSNSMSTTSSEWNNNNLITACMEMSSRLNENMSNLSHDSGIKSDKSLSTICDNNSNHDENVNYNWDRTLSNILIESANNESQQQNDSDTECSSSEDENDASTDHNSQDGVIDNANDVFPLPEQQTQDNEVHFELPLDYQDNLPPPPTATQALPTIPTMQATASHYQQPITIPNDNLYPNQSIPPPVYSNLQELKLNAAKKFGANTLSRISIKDRGNLIQAFNEYPESNIEESSTSFLGNSDKDKPTIPKIPTSQTKATAGKIQEAFHRSQSSVPVSVNDENPPSFNYYNDPESSVNATKIPLKGDSTIKPSMIRRGSFTTEMQVPQTPKNFNTVRKSSTQERTPLNMYSNKNRGRSMSVTREIENDHESPEKSSEDFNAIREILKRQRIVNRINGEATKPVTLPKPELPKKQSPSSNYMAYEYSNTLSSPVALRSNRFFNDRMLRQTNPNAPSGQNIQQMKYQQSRIPSDRDHDIDSAAGEEPACNDFNMSTGPEPIPSMHIERKDDKFKHQLIQMLHSSKSQEAARVAQIPASQHASNISSFYHGNPNHPNHPSHPNNNSSHQKSRTKSTIPNSKYCY
Sbjct:   31 LKFHNSI-------KLMTLSSSDLLDSLHSVCDIASKSPCCIKNTGISLTKLVLRQKKIEQKVSTLNSYLNENLSSELDKFLVEWRKTSLNLKRERDHDWKKANLEYQKSLAEVERTEKKLRKKNAGKVGLSETASLQIDYANQDAQNKRRYVEELERSAMRRAAIEERQRFKQFLVLLKPILDCQLSMREDLDNLEEVVSQLYGEKSENLDEFPEELEQNIQEHTIDNRSTTCIPRSYSTLSKQKSTASTGSHSSLNSNSMSTTSSEWNNNNLITACMEMSSRLNENMSNLSHDSGIKSDKSLSTICDNNSNHDENVNYNWDRTLSNILIESANNESQQQNDSDTECSSSEDENDASTDHNSQDGVIDNANDVFPLPEQQTQDNEVHFELPLDYQDNLPPPPTATQALPTIPTMQATASHYQQPITIPNDNLYPNQSIPPPVYSNLQELKLNAAKKFGANTLSRISIKDRGNLIQAFNEYPESNIEESSTSFLGNSDKDKPTIPKIPTSQTKATAGKIQEAFHRSQSSVPVSVNDENPPSFNYYNDPESSVNATKIPLKGDSTIKPSMIRRGSFTTEMQVPQTPKNFNTVRKSSTQERTPLNMYSNKNRGRSMSVTREIENDHESPEKSSEDFNAIREILKRQRIVNRINGEATKPVTLPKPELPKKQSPSSNYMAYEYSNTLSSPVALRSNRFFNDRMLRQTNPNAPSGQNIQQMKYQQSRIPSDRDHDIDSAAGEEPACNDFNMSTGPEPIPSMHIERKDDKFKHQLIQMLHSSKSQEAARVAQIPASQHASNISSFYHGNPNHPNHPSHPNNNSSHQKSRTKSTIPNSKYCY 859

[Close]

BLAST of IMD domain-containing protein vs. Planmine SMEST
Match: SMESG000038660.1 (SMESG000038660.1)

HSP 1 Score: 1483 bits (3838), Expect = 0.000e+0
Identity = 823/836 (98.44%), Postives = 824/836 (98.56%), Query Frame = 1

Query:    1 LKFHNSINLINFE*RLMTXXXXXXXXXXHSVCDIASKSPCCIKNTGISLTKLVLRQKKIEQKVSTLNSYLNENLSSELDKFLVEWRKTSLNLKRERDHDWKKANLEYQKSLAEVERTEKKLRKKNAGKVGLSETASLQIDYANQDAQNKRRYVEELERSAMRRAAIEERQRFKQFLVLLKPILDCQLSMREDLDNLEEVVSQLYGEKSENLDEFPEELEQNIQEHTIDNRSTTCIPRSYSTLSKQKXXXXXXXXXXXXXXXXXXXXXXXXXXXLITACMEMSSRLNENMSNLSHDSGIKSDKSLSTICDNNSNHDENVNYNWDRTLSNILIESANNESQQQNXXXXXXXXXXXXXXASTDHNSQDGVIDNANDVFPLPEQQTQDNEVHFELPLDYQDNXXXXXXXXXXXXXXXXMQATASHYQQPITIPNDNLYPNQSIPPPVYSNLQELKLNAAKKFGANTLSRISIKDRGNLIQAFNEYPESNIEESSTSFLGNSDKDKPTIPKIPTSQTKATAGKIQEAFHRSQSSVPVSVNDENPPSFNYYNDPESSVNATKIPLKGDSTIKPSMIRRGSFTTEMQVPQTPKNFNTVRKSSTQERTPLNMYSNKNRGRSMSVTREIENDHESPEKSSEDFNAIREILKRQRIVNRINGEATKPVTLPKPELPKKQSPSSNYMAYEYSNTLSSPVALRSNRFFNDRMLRQTNPNAPSGQNIQQMKYQQSRIPSDRDHDIDSAAGEEPACNDFNMSTGPEPIPSMHIERKDDKFKHQLIQMLHSSKSQEAARVAQIPASQHASNISSFYHGXXXXXXXXXXXXXXXXXQKSRTKSTIPNSKYCY 2508
            LKFHNSI       +LMTLSSSDLLDSLHSVCDIASKSPCCIKNTGISLTKLVLRQKKIEQKVSTLNSYLNENLSSELDKFLVEWRKTSLNLKRERDHDWKKANLEYQKSLAEVERTEKKLRKKNAGKVGLSETASLQIDYANQDAQNKRRYVEELERSAMRRAAIEERQRFKQFLVLLKPILDCQLSMREDLDNLEEVVSQLYGEKSENLDEFPEELEQNIQEHTIDNRSTTCIPRSYSTLSKQKSTASTGSHSSLNSNSMSTTSSEWNNNNLITACMEMSSRLNENMSNLSHDSGIKSDKSLSTICDNNSNHDENVNYNWDRTLSNILIESANNESQQQNDSDTECSSSEDENDASTDHNSQDGVIDNANDVFPLPEQQTQDNEVHFELPLDYQDNLPPPPTATQALPTIPTMQATASHYQQPITIPNDNLYPNQSIPPPVYSNLQELKLNAAKKFGANTLSRISIKDRGNLIQAFNEYPESNIEESSTSFLGNSDKDKPTIPKIPTSQTKATAGKIQEAFHRSQSSVPVSVNDENPPSFNYYNDPESSVNATKIPLKGDSTIKPSMIRRGSFTTEMQVPQTPKNFNTVRKSSTQERTPLNMYSNKNRGRSMSVTREIENDHESPEKSSEDFNAI     RQRIVNRINGEATKPVTLPKPELPKKQSPSSNYMAYEYSNTLSSPVALRSNRFFNDRMLRQTNPNAPSGQNIQQMKYQQSRIPSDRDHDIDSAAGEEPACNDFNMSTGPEPIPSMHIERKDDKFKHQLIQMLHSSKSQEAARVAQIPASQHASNISSFYHGNPNHPNHPSHPNNNSSHQKSRTKSTIPNSKYCY
Sbjct:   31 LKFHNSI-------KLMTLSSSDLLDSLHSVCDIASKSPCCIKNTGISLTKLVLRQKKIEQKVSTLNSYLNENLSSELDKFLVEWRKTSLNLKRERDHDWKKANLEYQKSLAEVERTEKKLRKKNAGKVGLSETASLQIDYANQDAQNKRRYVEELERSAMRRAAIEERQRFKQFLVLLKPILDCQLSMREDLDNLEEVVSQLYGEKSENLDEFPEELEQNIQEHTIDNRSTTCIPRSYSTLSKQKSTASTGSHSSLNSNSMSTTSSEWNNNNLITACMEMSSRLNENMSNLSHDSGIKSDKSLSTICDNNSNHDENVNYNWDRTLSNILIESANNESQQQNDSDTECSSSEDENDASTDHNSQDGVIDNANDVFPLPEQQTQDNEVHFELPLDYQDNLPPPPTATQALPTIPTMQATASHYQQPITIPNDNLYPNQSIPPPVYSNLQELKLNAAKKFGANTLSRISIKDRGNLIQAFNEYPESNIEESSTSFLGNSDKDKPTIPKIPTSQTKATAGKIQEAFHRSQSSVPVSVNDENPPSFNYYNDPESSVNATKIPLKGDSTIKPSMIRRGSFTTEMQVPQTPKNFNTVRKSSTQERTPLNMYSNKNRGRSMSVTREIENDHESPEKSSEDFNAI-----RQRIVNRINGEATKPVTLPKPELPKKQSPSSNYMAYEYSNTLSSPVALRSNRFFNDRMLRQTNPNAPSGQNIQQMKYQQSRIPSDRDHDIDSAAGEEPACNDFNMSTGPEPIPSMHIERKDDKFKHQLIQMLHSSKSQEAARVAQIPASQHASNISSFYHGNPNHPNHPSHPNNNSSHQKSRTKSTIPNSKYCY 854

[Close]

BLAST of IMD domain-containing protein vs. Planmine SMEST
Match: SMESG000031527.1 (SMESG000031527.1)

HSP 1 Score: 135.961 bits (341), Expect = 6.383e-33
Identity = 68/182 (37.36%), Postives = 119/182 (65.38%), Query Frame = 1

Query:  133 TGISLTKLVLRQKKIEQKVSTLNSYLNENLSSELDKFLVEWRKTSLNLKRERDHDWKKANLEYQKSLAEVERTEKKLRKK-NAGKVGLSETASLQIDYANQDAQNKRRYVEELERSAMRRAAIEERQRFKQFLVLLKPILDCQLSMREDLDNLEEVVSQLYGEKSENLDEFPEELEQNIQEH 675
             G  L+ + +++K I  K+S LNS +  NL+S+L   +  W++T  N+K++   D K+A ++ +K+ +E  + E K  K+    K  LS+T SLQIDYA Q+ QNK+R++EELER ++R+   EER R+KQF+  L+P+LD QLSM+ +L+ L+ +  +LY   +++L   P +++  ++++
Sbjct:   72 AGNLLSDIGIQEKSIANKLSVLNSSVQNNLASKLSFHIDSWKRTIANIKKDCHTDRKRAKIDLKKAESEFSKLESKSNKRLTINKFSLSDTFSLQIDYAKQNLQNKQRFLEELERCSLRKVVCEERNRYKQFIDCLRPVLDAQLSMKAELEELQLLYDKLYSSSTDDLSILPPDIDAYVRQY 253

[Close]

BLAST of IMD domain-containing protein vs. Planmine SMEST
Match: SMESG000038576.1 (SMESG000038576.1)

HSP 1 Score: 95.5153 bits (236), Expect = 6.477e-20
Identity = 55/170 (32.35%), Postives = 101/170 (59.41%), Query Frame = 1

Query:   91 VCDIASKSPCCI-KNTGISLTKLVLRQKKIEQKVSTLNSYLNENLSSELDKFLVEWRKTSLNLKRERDHDWKKANLEYQKSLAEVERTEKKLRKKNAGKVGLSETASLQIDYANQDAQNKRRYVEELERSAMRRAAIEERQRFKQFLVLLKPILDCQLSMREDLDNLEEV 597
            + D+A+ S     K+ G SLT+L LRQ+ +  K+ T+N  +   +   + + L EW++ +L + ++R  + ++A  E +K+  E  R +KK  K+ + K GL  +  +Q++ A ++A +K + +E +E   +RR  IEER RF  F+  L P+L+CQ++M  ++  LEE+
Sbjct:   60 IADLATNSSALASKDIGTSLTRLSLRQRSLHLKMKTMNESMACRIIDPMQQRLDEWKRCNLQIDKDRIKETRRAKSELKKASEEKNRLQKKAMKRGSMK-GLG-SLQMQVEVALKEAADKYQALENIEYDCVRRVVIEERSRFCYFVNCLMPVLECQINMFSEMQTLEEI 227

[Close]

BLAST of IMD domain-containing protein vs. Planmine SMEST
Match: SMESG000028682.1 (SMESG000028682.1)

HSP 1 Score: 90.8929 bits (224), Expect = 2.046e-18
Identity = 59/194 (30.41%), Postives = 110/194 (56.70%), Query Frame = 1

Query:   91 VCDIASKSPCCIKNTGISLTKLVLRQKKIEQKVSTLNSYLNENLSSELDKFLVEWRKTSLNLKRERDHDWKKANLEYQKSLAEVERTEKKLRKKNAGKVGLSETASLQIDYANQDAQNKRRYVEELERSAMRRAAIEERQRFKQFLVLLKPILDCQLSMREDLDNLEEVVSQLYGEKSENLDEFPEELEQNIQE 672
            + D+A+ +    K  G S T+L +RQ+ +E K+ TL+++L  +LS+ +   L +W++ S  L ++R  + KKA   ++K+  E  R +KK  K+ + + GL    + Q++ A ++A  K   ++ +E   +RRA   ER+RF      +KP+L+ Q+S+  D+ +L+E++  L    +   D  P E E+ IQ+
Sbjct:   60 IADLATDTQGATKEIGASFTRLCMRQRLMECKIKTLSNHLIGSLSNPVQDKLEDWKRYSNQLDKDRIKETKKAKTHWKKASGESVRLQKKAVKRGSMR-GLGSLQN-QVEGALKNAAEKYTSLQTVESIYLRRAMTHERERFCFLFSCMKPVLESQISLLTDISSLDELMKTLT-LNTVFPDRLPVESEEIIQQ 250

The following BLAST results are available for this feature:

BLAST of IMD domain-containing protein vs. Ensembl Human
BLAST of IMD domain-containing protein vs. Ensembl Celegans
BLAST of IMD domain-containing protein vs. Ensembl Fly
BLAST of IMD domain-containing protein vs. Ensembl Zebrafish
BLAST of IMD domain-containing protein vs. Ensembl Xenopus
BLAST of IMD domain-containing protein vs. Ensembl Mouse
BLAST of IMD domain-containing protein vs. UniProt/SwissProt
BLAST of IMD domain-containing protein vs. TrEMBL
BLAST of IMD domain-containing protein vs. Ensembl Cavefish
BLAST of IMD domain-containing protein vs. Ensembl Sea Lamprey
BLAST of IMD domain-containing protein vs. Ensembl Yeast
BLAST of IMD domain-containing protein vs. Ensembl Nematostella
BLAST of IMD domain-containing protein vs. Ensembl Medaka
BLAST of IMD domain-containing protein vs. Planmine SMEST

BLAST of IMD domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
MTSS2	2.890e-19	29.90	MTSS I-BAR domain containing 2 [Source:HGNC Symbol...	[more]
MTSS2	6.589e-18	29.38	MTSS I-BAR domain containing 2 [Source:HGNC Symbol...	[more]
MTSS1	2.169e-17	30.93	MTSS I-BAR domain containing 1 [Source:HGNC Symbol...	[more]
MTSS1	2.959e-17	30.93	MTSS I-BAR domain containing 1 [Source:HGNC Symbol...	[more]
MTSS1	3.879e-17	30.41	MTSS I-BAR domain containing 1 [Source:HGNC Symbol...	[more]

BLAST of IMD domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of IMD domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
mim	7.565e-15	25.71	gene:FBgn0053558 transcript:FBtr0332943	[more]
mim	7.817e-15	27.33	gene:FBgn0053558 transcript:FBtr0332944	[more]
mim	8.328e-15	27.33	gene:FBgn0053558 transcript:FBtr0302035	[more]
mim	9.362e-15	27.33	gene:FBgn0053558 transcript:FBtr0302577	[more]
mim	9.544e-15	27.33	gene:FBgn0053558 transcript:FBtr0113470	[more]

BLAST of IMD domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 4


Match Name	E-value	Identity	Description
mtss1	4.603e-19	30.73	MTSS I-BAR domain containing 1 [Source:ZFIN;Acc:ZD...	[more]
mtss1la	1.269e-18	28.13	MTSS I-BAR domain containing 2a [Source:ZFIN;Acc:Z...	[more]
mtss1lb	3.184e-18	28.90	MTSS I-BAR domain containing 2b [Source:ZFIN;Acc:Z...	[more]
mtss1la	1.440e-17	28.13	MTSS I-BAR domain containing 2a [Source:ZFIN;Acc:Z...	[more]

BLAST of IMD domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
acss2.2	4.993e-21	31.79	acyl-CoA synthetase short-chain family member 2, g...	[more]
acss2.2	6.812e-21	31.79	acyl-CoA synthetase short-chain family member 2, g...	[more]
acss2.2	7.413e-20	31.79	acyl-CoA synthetase short-chain family member 2, g...	[more]
acss2.2	8.394e-20	31.79	acyl-CoA synthetase short-chain family member 2, g...	[more]
gphn	9.027e-18	31.25	gephyrin [Source:Xenbase;Acc:XB-GENE-989642]	[more]

BLAST of IMD domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Mtss2	2.665e-18	30.64	MTSS I-BAR domain containing 2 [Source:MGI Symbol;...	[more]
Mtss1	6.064e-18	30.93	MTSS I-BAR domain containing 1 [Source:MGI Symbol;...	[more]
Mtss2	5.265e-17	30.00	MTSS I-BAR domain containing 2 [Source:MGI Symbol;...	[more]
Mtss2	1.032e-11	32.50	MTSS I-BAR domain containing 2 [Source:MGI Symbol;...	[more]
Mtss2	6.783e-10	34.23	MTSS I-BAR domain containing 2 [Source:MGI Symbol;...	[more]

BLAST of IMD domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 4


Match Name	E-value	Identity	Description
sp\|Q765P7\|MTSS2_HUMAN	1.388e-18	29.90	Protein MTSS 2 OS=Homo sapiens OX=9606 GN=MTSS2 PE...	[more]
sp\|Q6P9S0\|MTSS2_MOUSE	1.864e-17	30.64	Protein MTSS 2 OS=Mus musculus OX=10090 GN=Mtss2 P...	[more]
sp\|O43312\|MTSS1_HUMAN	1.041e-16	30.93	Protein MTSS 1 OS=Homo sapiens OX=9606 GN=MTSS1 PE...	[more]
sp\|Q8R1S4\|MTSS1_MOUSE	2.065e-16	30.41	Protein MTSS 1 OS=Mus musculus OX=10090 GN=Mtss1 P...	[more]

BLAST of IMD domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A1Y1KH05	9.950e-22	36.42	IMD domain-containing protein OS=Photinus pyralis ...	[more]
A0A1Y1KHF1	1.083e-21	35.42	IMD domain-containing protein OS=Photinus pyralis ...	[more]
A0A5N4B4P3	1.133e-21	35.42	Uncharacterized protein OS=Photinus pyralis OX=705...	[more]
U4U350	1.130e-20	34.95	IMD domain-containing protein OS=Dendroctonus pond...	[more]
A0A2R2MT41	2.863e-20	34.62	MTSS1-like protein OS=Lingula unguis OX=7574 GN=LO...	[more]

BLAST of IMD domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
mtss1	6.803e-21	31.77	MTSS I-BAR domain containing 1 [Source:ZFIN;Acc:ZD...	[more]
mtss1	1.594e-20	31.77	MTSS I-BAR domain containing 1 [Source:ZFIN;Acc:ZD...	[more]
mtss1	1.863e-20	31.77	MTSS I-BAR domain containing 1 [Source:ZFIN;Acc:ZD...	[more]
mtss1la	3.796e-19	29.17	MTSS1-like protein [Source:NCBI gene;Acc:103039604...	[more]
mtss1la	4.176e-19	29.17	MTSS1-like protein [Source:NCBI gene;Acc:103039604...	[more]

BLAST of IMD domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 4


Match Name	E-value	Identity	Description
ENSPMAT00000001774.1	2.845e-20	29.55	pep scaffold:Pmarinus_7.0:GL476804:163249:239367:-...	[more]
ENSPMAT00000002039.1	4.331e-11	29.85	pep scaffold:Pmarinus_7.0:GL477038:84867:99356:-1 ...	[more]
ENSPMAT00000002029.1	6.566e-11	29.85	pep scaffold:Pmarinus_7.0:GL477038:82432:99356:-1 ...	[more]
ENSPMAT00000002035.1	6.964e-11	29.85	pep scaffold:Pmarinus_7.0:GL477038:82432:99356:-1 ...	[more]

BLAST of IMD domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of IMD domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of IMD domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
mtss1la	5.321e-19	29.38	MTSS1-like protein [Source:NCBI gene;Acc:101164641...	[more]
mtss1la	6.523e-19	29.38	MTSS1-like protein [Source:NCBI gene;Acc:101164641...	[more]
mtss1la	7.581e-19	29.38	MTSS1-like protein [Source:NCBI gene;Acc:101164641...	[more]
MTSS1	1.088e-18	29.82	metastasis suppressor protein 1 [Source:NCBI gene;...	[more]
ENSORLT00000000819.2	2.059e-18	27.94	MTSS I-BAR domain containing 1 [Source:NCBI gene;A...	[more]

BLAST of IMD domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000038660.1	0.000e+0	99.04	SMESG000038660.1	[more]
SMESG000038660.1	0.000e+0	98.44	SMESG000038660.1	[more]
SMESG000031527.1	6.383e-33	37.36	SMESG000031527.1	[more]
SMESG000038576.1	6.477e-20	32.35	SMESG000038576.1	[more]
SMESG000028682.1	2.046e-18	30.41	SMESG000028682.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30008314 ID=SMED30008314|Name=IMD domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=2693bp
CTCAAATTTCACAATTCCATCAATTTAATTAATTTTGAATGAAGGTTAAT
GACTCTGTCTTCAAGTGATCTCCTTGATAGCTTACATTCTGTTTGTGATA
TAGCTAGTAAAAGCCCATGTTGTATCAAAAATACGGGCATCAGTTTAACG
AAGCTTGTATTAAGACAAAAGAAAATTGAGCAAAAAGTCTCAACTCTAAA
CAGCTATTTAAATGAAAATCTATCATCGGAACTTGATAAATTTCTAGTTG
AATGGCGCAAAACTAGTTTGAACCTGAAACGTGAACGCGACCATGATTGG
AAAAAGGCAAATCTTGAATATCAAAAATCATTGGCGGAAGTCGAAAGAAC
AGAAAAAAAATTACGCAAGAAAAATGCCGGAAAAGTTGGATTATCAGAAA
CAGCTAGCTTGCAAATTGACTATGCTAACCAGGATGCACAAAACAAACGC
CGATATGTTGAAGAATTGGAACGGTCGGCGATGCGGAGAGCAGCCATTGA
AGAGCGACAACGTTTTAAACAATTTCTCGTACTTTTAAAGCCAATTCTTG
ATTGTCAATTATCAATGCGAGAAGACCTAGACAATTTGGAAGAAGTGGTT
AGTCAACTGTATGGAGAAAAATCGGAAAATTTGGATGAATTTCCAGAAGA
ATTGGAACAAAATATACAAGAACACACAATAGATAACCGATCAACGACTT
GTATTCCAAGGAGCTATTCCACGCTTTCTAAACAGAAAAGTACGGCATCA
ACTGGAAGCCACAGTAGTCTGAATAGCAACAGTATGAGTACAACATCATC
AGAATGGAATAATAATAATCTTATTACCGCATGCATGGAGATGTCATCTC
GTCTGAATGAAAACATGAGCAATTTATCACACGATTCTGGAATTAAAAGT
GACAAAAGTTTATCCACAATATGCGATAACAATTCAAACCATGACGAAAA
TGTCAATTACAATTGGGACAGAACTTTGTCCAATATTCTAATTGAGTCTG
CAAATAATGAATCACAGCAGCAAAATGATTCTGATACAGAATGCTCATCA
AGTGAAGATGAAAATGATGCATCAACTGATCATAATAGCCAAGATGGAGT
AATTGACAATGCAAATGATGTTTTTCCATTGCCCGAGCAACAAACCCAAG
ACAATGAAGTCCATTTCGAATTGCCACTAGACTATCAAGATAACTTACCT
CCTCCACCGACTGCCACTCAGGCGTTACCTACAATCCCCACTATGCAAGC
CACCGCCTCACATTATCAGCAACCCATTACTATACCAAATGATAATTTAT
ACCCTAACCAATCTATTCCACCACCAGTCTATTCAAATCTGCAGGAATTG
AAATTAAATGCCGCTAAAAAGTTTGGAGCTAATACACTGTCAAGGATTTC
TATTAAAGATCGCGGTAATTTAATACAAGCTTTTAATGAATATCCAGAAT
CAAATATCGAAGAATCATCAACTTCATTTCTTGGAAATTCAGATAAAGAT
AAGCCAACTATTCCGAAAATACCAACGAGTCAAACAAAAGCCACCGCAGG
GAAAATCCAAGAAGCATTTCATAGATCTCAGTCATCGGTTCCAGTCAGTG
TAAATGATGAGAATCCACCAAGTTTCAATTATTACAATGATCCAGAAAGC
TCTGTGAATGCCACAAAAATCCCCTTGAAAGGCGATTCGACAATTAAACC
ATCGATGATTCGCCGAGGCTCATTCACCACTGAAATGCAAGTGCCACAAA
CACCTAAAAACTTCAATACAGTCCGCAAGAGTTCAACACAAGAAAGAACA
CCATTAAATATGTACTCTAACAAAAATCGTGGCCGCAGTATGAGCGTTAC
AAGAGAAATTGAAAACGATCACGAAAGTCCAGAAAAGTCATCTGAAGATT
TCAACGCGATTCGAGAGATTTTAAAGCGACAACGAATTGTGAATCGCATC
AATGGTGAAGCCACCAAACCTGTAACTCTTCCTAAGCCGGAATTGCCTAA
AAAACAATCACCAAGTTCTAATTATATGGCATATGAATATTCCAACACGC
TTTCCAGTCCAGTTGCGTTGCGATCGAATCGGTTTTTCAATGATCGGATG
CTGAGACAAACTAATCCAAACGCACCCAGTGGACAGAATATCCAGCAAAT
GAAATATCAGCAATCACGGATACCATCTGATCGCGATCATGACATTGATT
CAGCAGCTGGTGAGGAGCCTGCTTGTAATGATTTCAATATGTCAACTGGT
CCTGAACCGATACCATCGATGCATATTGAGAGGAAGGACGATAAATTTAA
GCATCAATTAATTCAAATGTTACACTCATCGAAATCCCAAGAAGCTGCAA
GGGTAGCTCAAATTCCTGCTAGTCAACATGCTTCGAATATATCATCATTT
TATCACGGCAATCCCAACCATCCCAACCATCCGAGCCACCCCAATAACAA
CAGCAGTCACCAGAAATCACGCACGAAATCCACGATTCCCAATTCCAAAT
ATTGCTACTAAATTATCAACCGATACCCATTCAATATTTGTACAAATGTG
CTCTAGTGCAATCCGTTTTTATTATTCACTACTATTAATGAGTTTTAATT
AATTTATTTTTCATTATGTTCTTTATTTAAAAAGTTACTTAATATTTATT
ATTTATATTTTATATAAAAGTGAACATCAAAGTTAGAATACTG

protein sequence of SMED30008314-orf-1

>SMED30008314-orf-1 ID=SMED30008314-orf-1|Name=SMED30008314-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=821bp
MTLSSSDLLDSLHSVCDIASKSPCCIKNTGISLTKLVLRQKKIEQKVSTL
NSYLNENLSSELDKFLVEWRKTSLNLKRERDHDWKKANLEYQKSLAEVER
TEKKLRKKNAGKVGLSETASLQIDYANQDAQNKRRYVEELERSAMRRAAI
EERQRFKQFLVLLKPILDCQLSMREDLDNLEEVVSQLYGEKSENLDEFPE
ELEQNIQEHTIDNRSTTCIPRSYSTLSKQKSTASTGSHSSLNSNSMSTTS
SEWNNNNLITACMEMSSRLNENMSNLSHDSGIKSDKSLSTICDNNSNHDE
NVNYNWDRTLSNILIESANNESQQQNDSDTECSSSEDENDASTDHNSQDG
VIDNANDVFPLPEQQTQDNEVHFELPLDYQDNLPPPPTATQALPTIPTMQ
ATASHYQQPITIPNDNLYPNQSIPPPVYSNLQELKLNAAKKFGANTLSRI
SIKDRGNLIQAFNEYPESNIEESSTSFLGNSDKDKPTIPKIPTSQTKATA
GKIQEAFHRSQSSVPVSVNDENPPSFNYYNDPESSVNATKIPLKGDSTIK
PSMIRRGSFTTEMQVPQTPKNFNTVRKSSTQERTPLNMYSNKNRGRSMSV
TREIENDHESPEKSSEDFNAIREILKRQRIVNRINGEATKPVTLPKPELP
KKQSPSSNYMAYEYSNTLSSPVALRSNRFFNDRMLRQTNPNAPSGQNIQQ
MKYQQSRIPSDRDHDIDSAAGEEPACNDFNMSTGPEPIPSMHIERKDDKF
KHQLIQMLHSSKSQEAARVAQIPASQHASNISSFYHGNPNHPNHPSHPNN
NSSHQKSRTKSTIPNSKYCY*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000099	neuron
PLANA:0000101	muscle cell
PLANA:0003116	parenchymal cell

Vocabulary: **INTERPRO**
Term	Definition
IPR027267	AH/BAR_dom_sf
IPR030127	MTSS1/MTSS2
IPR013606	I-BAR_dom

Vocabulary: **biological process**
Term	Definition
GO:0007009	plasma membrane organization

Vocabulary: **molecular function**
Term	Definition
GO:0003779	actin binding

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
None	No IPR available	COILS	Coil	Coil	coord: 88..108
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 318..349
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 229..250
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 782..820
None	No IPR available	PANTHER	PTHR15708:SF14	METASTASIS SUPPRESSOR 1	coord: 3..303
IPR027267	AH/BAR domain superfamily	GENE3D	G3DSA:1.20.1270.60		coord: 1..208 e-value: 3.7E-37 score: 129.6
IPR027267	AH/BAR domain superfamily	SUPERFAMILY	SSF103657	BAR/IMD domain-like	coord: 5..208
IPR013606	IMD/I-BAR domain	PFAM	PF08397	IMD	coord: 4..185 e-value: 2.5E-18 score: 66.3
IPR030127	I-BAR domain containing protein MTSS1/MTSS2	PANTHER	PTHR15708	ACTIN BUNDLING/MISSING IN METASTASIS-RELATED	coord: 3..303

Main menu

IMD domain-containing protein

Zeng et. al., 2018

▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Davies et. al., 2017

PAGE et. al., 2020

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 7

Owlery

blazegraph-runner