Protein kinase domain-containing protein
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30008292 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 8
Homology
BLAST of Protein kinase domain-containing protein vs. Ensembl Human
Match: MAP3K15 (mitogen-activated protein kinase kinase kinase 15 [Source:HGNC Symbol;Acc:HGNC:31689]) HSP 1 Score: 132.494 bits (332), Expect = 6.027e-31 Identity = 89/263 (33.84%), Postives = 133/263 (50.57%), Query Frame = 2
Query: 1457 IDRGYYSILLKAKIKSKDKDIVLKKYTEIDLPDLNKNNVLLKELSIFQTLKSHHRFLKLFGIYKEENYFYIAMENMKGGSIKTHIK-KNKPLDEKQIAFWSKQILEGLKYLHDQEFVYRDLKTSNILIDDKND-VKLPSVSLSKYLHDYNRKPEQMGYQDNLPLRYMAPEILQQHP--YGIKADVWSFGAIIVEMVTGIQPYSELNETDAIQRIIQDRTIKYNTT-AISHNLKEFIGLCLIFNPEERSSDDKLMNHSFLNE*N 2230
+ +G Y I+ + S I +K EI D + L +E+++ + LK H ++ G E Y I ME + GGS+ ++ K P+ E I F++KQILEGLKYLH+ + V+RD+K N+L++ + VK+ SK L N E L+YMAPEI+ Q P YG AD+WS G I+EM T P+ EL E A + I A+S + FI C +P +R++ +L+ FL + N
Sbjct: 658 LGKGTYGIVYAGRDLSNQVRIAIK---EIPERDSRYSQPLHEEIALHKYLK-HRNIVQYLGSVSENGYIKIFMEQVPGGSLSALLRSKWGPMKEPTIKFYTKQILEGLKYLHENQIVHRDIKGDNVLVNTYSGVVKISDFGTSKRLAGVNPCTETF----TGTLQYMAPEIIDQGPRGYGAPADIWSLGCTIIEMATSKPPFHELGEPQAAMFKVGMFKIHPEIPEALSAEARAFILSCFEPDPHKRATTAELLREGFLRQVN 912
BLAST of Protein kinase domain-containing protein vs. Ensembl Human
Match: MAP3K5 (mitogen-activated protein kinase kinase kinase 5 [Source:HGNC Symbol;Acc:HGNC:6857]) HSP 1 Score: 128.257 bits (321), Expect = 1.237e-29 Identity = 89/261 (34.10%), Postives = 136/261 (52.11%), Query Frame = 2
Query: 1457 IDRGYYSILLKAKIKSKDKDIVLKKYTEIDLPDLNKNNVLLKELSIFQTLKSHHRFLKLFGIYKEENYFYIAMENMKGGSIKTHIK-KNKPL--DEKQIAFWSKQILEGLKYLHDQEFVYRDLKTSNILIDDKNDV-KLPSVSLSKYLHDYNRKPEQMGYQDNLPLRYMAPEILQQHP--YGIKADVWSFGAIIVEMVTGIQPYSELNETDAIQ-RIIQDRTIKYNTTAISHNLKEFIGLCLIFNPEERSSDDKLMNHSFL 2218
+ +G Y I+ + S I +K EI D + L +E+++ + LK H ++ G + E + I ME + GGS+ ++ K PL +E+ I F++KQILEGLKYLHD + V+RD+K N+LI+ + V K+ SK L N E L+YMAPEI+ + P YG AD+WS G I+EM TG P+ EL E A ++ + ++S K FI C +P++R+ + L+ FL
Sbjct: 686 LGKGTYGIVYAGRDLSNQVRIAIK---EIPERDSRYSQPLHEEIALHKHLK-HKNIVQYLGSFSENGFIKIFMEQVPGGSLSALLRSKWGPLKDNEQTIGFYTKQILEGLKYLHDNQIVHRDIKGDNVLINTYSGVLKISDFGTSKRLAGINPCTETF----TGTLQYMAPEIIDKGPRGYGKAADIWSLGCTIIEMATGKPPFYELGEPQAAMFKVGMFKVHPEIPESMSAEAKAFILKCFEPDPDKRACANDLLVDEFL 938
BLAST of Protein kinase domain-containing protein vs. Ensembl Human
Match: STK4 (serine/threonine kinase 4 [Source:HGNC Symbol;Acc:HGNC:11408]) HSP 1 Score: 122.479 bits (306), Expect = 7.274e-29 Identity = 81/262 (30.92%), Postives = 137/262 (52.29%), Query Frame = 2
Query: 1442 EVIEEIDRGYYSILLKAKIKSKDKDIVLKKY-TEIDLPDLNKNNVLLKELSIFQTLKSHHRFLKLFGIYKEENYFYIAMENMKGGSIKTHIK-KNKPLDEKQIAFWSKQILEGLKYLHDQEFVYRDLKTSNILIDDKNDVKLPSVSLSKYLHDYNRKPEQMGYQDNLPLRYMAPEILQQHPYGIKADVWSFGAIIVEMVTGIQPYSELNETDAIQRIIQDRTIKYNTTAI-SHNLKEFIGLCLIFNPEERSSDDKLMNHSFL 2218
+V+E++ G Y + KA K + + +K+ E DL ++ +KE+SI Q S H +K +G Y + +I ME GS+ I+ +NK L E +IA + L+GL+YLH ++RD+K NIL++ + KL ++ L D K + P +MAPE++Q+ Y AD+WS G +EM G PY++++ AI I + + + S N +F+ CL+ +PE+R++ +L+ H F+
Sbjct: 31 DVLEKLGEGSYGSVYKAIHKETGQIVAIKQVPVESDLQEI------IKEISIMQQCDSPH-VVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILQSTLKGLEYLHFMRKIHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMAKRNTV---IGTPF-WMAPEVIQEIGYNCVADIWSLGITAIEMAEGKPPYADIHPMRAIFMIPTNPPPTFRKPELWSDNFTDFVKQCLVKSPEQRATATQLLQHPFV 281
BLAST of Protein kinase domain-containing protein vs. Ensembl Human
Match: STK4 (serine/threonine kinase 4 [Source:HGNC Symbol;Acc:HGNC:11408]) HSP 1 Score: 121.324 bits (303), Expect = 2.459e-28 Identity = 81/262 (30.92%), Postives = 137/262 (52.29%), Query Frame = 2
Query: 1442 EVIEEIDRGYYSILLKAKIKSKDKDIVLKKY-TEIDLPDLNKNNVLLKELSIFQTLKSHHRFLKLFGIYKEENYFYIAMENMKGGSIKTHIK-KNKPLDEKQIAFWSKQILEGLKYLHDQEFVYRDLKTSNILIDDKNDVKLPSVSLSKYLHDYNRKPEQMGYQDNLPLRYMAPEILQQHPYGIKADVWSFGAIIVEMVTGIQPYSELNETDAIQRIIQDRTIKYNTTAI-SHNLKEFIGLCLIFNPEERSSDDKLMNHSFL 2218
+V+E++ G Y + KA K + + +K+ E DL ++ +KE+SI Q S H +K +G Y + +I ME GS+ I+ +NK L E +IA + L+GL+YLH ++RD+K NIL++ + KL ++ L D K + P +MAPE++Q+ Y AD+WS G +EM G PY++++ AI I + + + S N +F+ CL+ +PE+R++ +L+ H F+
Sbjct: 31 DVLEKLGEGSYGSVYKAIHKETGQIVAIKQVPVESDLQEI------IKEISIMQQCDSPH-VVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILQSTLKGLEYLHFMRKIHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMAKRNTV---IGTPF-WMAPEVIQEIGYNCVADIWSLGITAIEMAEGKPPYADIHPMRAIFMIPTNPPPTFRKPELWSDNFTDFVKQCLVKSPEQRATATQLLQHPFV 281
BLAST of Protein kinase domain-containing protein vs. Ensembl Human
Match: STK3 (serine/threonine kinase 3 [Source:HGNC Symbol;Acc:HGNC:11406]) HSP 1 Score: 120.168 bits (300), Expect = 6.472e-28 Identity = 84/272 (30.88%), Postives = 141/272 (51.84%), Query Frame = 2
Query: 1442 EVIEEIDRGYYSILLKAKIKSKDKDIVLKKY-TEIDLPDLNKNNVLLKELSIFQTLKSHHRFLKLFGIYKEENYFYIAMENMKGGSIKTHIK-KNKPLDEKQIAFWSKQILEGLKYLHDQEFVYRDLKTSNILIDDKNDVKLPSVSLSKYLHDYNRKPEQMGYQDNLPLRYMAPEILQQHPYGIKADVWSFGAIIVEMVTGIQPYSELNETDAIQRIIQDRTIKYNTTAI-SHNLKEFIGLCLIFNPEERSSDDKLMNHSFLNE*NVKEFNI 2248
+V+E++ G Y + KA K + + +K+ E DL ++ +KE+SI Q S + +K +G Y + +I ME GS+ I+ +NK L E +IA K L+GL+YLH ++RD+K NIL++ + KL ++ L D K + P +MAPE++Q+ Y AD+WS G +EM G PY++++ AI I + + + S + +F+ CL+ NPE+R++ +L+ H F+ N K +I
Sbjct: 56 DVLEKLGEGSYGSVFKAIHKESGQVVAIKQVPVESDLQEI------IKEISIMQQCDSPY-VVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLIEDEIATILKSTLKGLEYLHFMRKIHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMAKRNTV---IGTPF-WMAPEVIQEIGYNCVADIWSLGITSIEMAEGKPPYADIHPMRAIFMIPTNPPPTFRKPELWSDDFTDFVKKCLVKNPEQRATATQLLQHPFIK--NAKPVSI 314
BLAST of Protein kinase domain-containing protein vs. Ensembl Celegans
Match: nsy-1 (Mitogen-activated protein kinase kinase kinase nsy-1 [Source:UniProtKB/Swiss-Prot;Acc:Q21029]) HSP 1 Score: 120.939 bits (302), Expect = 9.182e-28 Identity = 84/264 (31.82%), Postives = 137/264 (51.89%), Query Frame = 2
Query: 1457 IDRGYYSILLKAKIKSKDKDIVLKKYTEIDLPDLNKNNVLLKELSIFQTLKSHHRFLK-----LFGIYKEENYFYIAMENMKGGSIKTHIK-KNKPLDEKQIAFWSKQILEGLKYLHDQEFVYRDLKTSNILIDDKNDV-KLPSVSLSKYLHDYNRKPEQMGYQDNLPLRYMAPEILQ--QHPYGIKADVWSFGAIIVEMVTGIQPYSEL-NETDAIQRIIQDRTIKYNTTAISHNLKEFIGLCLIFNPEERSSDDKLMNHSFL 2218
+ +G Y + A+ + IV+K EI++ + L++E+S+ TL H ++ L G ++F I ME++ GGS+ + ++ K P++E + ++ KQILEGLKYLH+ + V+RD+K N+L++ + V K+ K L N E L+YMAPE++ Q YG AD+WSFG +VEM TG P+ E+ N A+ R+ +T T I+ + FI C + +R S L+ F+
Sbjct: 670 LGKGTYGTVYAARDMDTQRQIVVK---EIEVKYDEEVQPLMEEISLHSTL-CHANIVQYLGCDLVGKDGSNDHFLIFMEHVPGGSLSSLLRSKWGPMNENAMNYYGKQILEGLKYLHELKIVHRDIKGDNVLVNTYSGVCKISDFGTCKRLAGLNPVTETFTGT----LQYMAPEVIDHGQRGYGAPADIWSFGCTMVEMATGRPPFVEMQNPQAAMFRVGMFKTHPPIPTEITEKCRNFIKSCFLPEACDRPSAKDLLQDPFI 925
BLAST of Protein kinase domain-containing protein vs. Ensembl Celegans
Match: cst-2 (Caenorhabditis STE20-like kinase [Source:UniProtKB/TrEMBL;Acc:Q304D8]) HSP 1 Score: 117.087 bits (292), Expect = 9.269e-28 Identity = 82/261 (31.42%), Postives = 136/261 (52.11%), Query Frame = 2
Query: 1442 EVIEEIDRGYYSILLKAKIKSKDKDIVLKKYTEIDLPDLNKNNVLLKELSIFQTLKSHHRFLKLFGIYKEENYFYIAMENMKGGSIKTHIK-KNKPLDEKQIAFWSKQILEGLKYLHDQEFVYRDLKTSNILIDDKNDVKLPSVSLSKYLHDYNRKPEQMGYQDNLPLRYMAPEILQQHPYGIKADVWSFGAIIVEMVTGIQPYSELNETDAIQRIIQDRTIKYNTT-AISHNLKEFIGLCLIFNPEERSSDDKLMNHSFL 2218
+++ ++ G Y + KA I + ++ K +D DL + ++KE+SI Q KS + +K +G Y + + +I ME GSI ++ + KPL E++I+ + L+GL+YLHD + ++RD+K NIL++ KL ++ L D K + P +MAPE++++ Y KAD+WS G +EM G PYS+++ AI I + S +FI CLI PEER + +L H+F+
Sbjct: 36 DIVGKLGEGSYGSVHKA-IHRESGHVLAIKKVPVDT-DLQE---IIKEISIMQQCKSKY-VVKYYGSYFKHSDLWIVMEYCGAGSISDIMRARRKPLSEQEISAVLRDTLKGLQYLHDLKKIHRDIKAGNILLNTDGIAKLADFGVAGQLTDTMAKRNTV---IGTPF-WMAPEVIEEIGYDTKADIWSLGITAIEMAEGRPPYSDIHPMRAIFMIPTKPPPTFKKPEEWSSEFNDFIRSCLIKKPEERKTALRLCEHTFI 286
BLAST of Protein kinase domain-containing protein vs. Ensembl Celegans
Match: nsy-1 (Mitogen-activated protein kinase kinase kinase nsy-1 [Source:UniProtKB/Swiss-Prot;Acc:Q21029]) HSP 1 Score: 120.939 bits (302), Expect = 1.133e-27 Identity = 84/264 (31.82%), Postives = 137/264 (51.89%), Query Frame = 2
Query: 1457 IDRGYYSILLKAKIKSKDKDIVLKKYTEIDLPDLNKNNVLLKELSIFQTLKSHHRFLK-----LFGIYKEENYFYIAMENMKGGSIKTHIK-KNKPLDEKQIAFWSKQILEGLKYLHDQEFVYRDLKTSNILIDDKNDV-KLPSVSLSKYLHDYNRKPEQMGYQDNLPLRYMAPEILQ--QHPYGIKADVWSFGAIIVEMVTGIQPYSEL-NETDAIQRIIQDRTIKYNTTAISHNLKEFIGLCLIFNPEERSSDDKLMNHSFL 2218
+ +G Y + A+ + IV+K EI++ + L++E+S+ TL H ++ L G ++F I ME++ GGS+ + ++ K P++E + ++ KQILEGLKYLH+ + V+RD+K N+L++ + V K+ K L N E L+YMAPE++ Q YG AD+WSFG +VEM TG P+ E+ N A+ R+ +T T I+ + FI C + +R S L+ F+
Sbjct: 656 LGKGTYGTVYAARDMDTQRQIVVK---EIEVKYDEEVQPLMEEISLHSTL-CHANIVQYLGCDLVGKDGSNDHFLIFMEHVPGGSLSSLLRSKWGPMNENAMNYYGKQILEGLKYLHELKIVHRDIKGDNVLVNTYSGVCKISDFGTCKRLAGLNPVTETFTGT----LQYMAPEVIDHGQRGYGAPADIWSFGCTMVEMATGRPPFVEMQNPQAAMFRVGMFKTHPPIPTEITEKCRNFIKSCFLPEACDRPSAKDLLQDPFI 911
BLAST of Protein kinase domain-containing protein vs. Ensembl Celegans
Match: cst-1 (Serine/threonine-protein kinase cst-1 Serine/threonine-protein kinase cst-1 37kDa subunit Serine/threonine-protein kinase cst-1 18kDa subunit [Source:UniProtKB/Swiss-Prot;Acc:Q9NB31]) HSP 1 Score: 117.087 bits (292), Expect = 2.329e-27 Identity = 82/261 (31.42%), Postives = 136/261 (52.11%), Query Frame = 2
Query: 1442 EVIEEIDRGYYSILLKAKIKSKDKDIVLKKYTEIDLPDLNKNNVLLKELSIFQTLKSHHRFLKLFGIYKEENYFYIAMENMKGGSIKTHIK-KNKPLDEKQIAFWSKQILEGLKYLHDQEFVYRDLKTSNILIDDKNDVKLPSVSLSKYLHDYNRKPEQMGYQDNLPLRYMAPEILQQHPYGIKADVWSFGAIIVEMVTGIQPYSELNETDAIQRIIQDRTIKYNTT-AISHNLKEFIGLCLIFNPEERSSDDKLMNHSFL 2218
+++ ++ G Y + KA I + ++ K +D DL + ++KE+SI Q KS + +K +G Y + + +I ME GSI ++ + KPL E++I+ + L+GL+YLHD + ++RD+K NIL++ KL ++ L D K + P +MAPE++++ Y KAD+WS G +EM G PYS+++ AI I + S +FI CLI PEER + +L H+F+
Sbjct: 36 DIVGKLGEGSYGSVHKA-IHRESGHVLAIKKVPVDT-DLQE---IIKEISIMQQCKSKY-VVKYYGSYFKHSDLWIVMEYCGAGSISDIMRARRKPLSEQEISAVLRDTLKGLQYLHDLKKIHRDIKAGNILLNTDGIAKLADFGVAGQLTDTMAKRNTV---IGTPF-WMAPEVIEEIGYDTKADIWSLGITAIEMAEGRPPYSDIHPMRAIFMIPTKPPPTFKKPEEWSSEFNDFIRSCLIKKPEERKTALRLCEHTFI 286
BLAST of Protein kinase domain-containing protein vs. Ensembl Celegans
Match: cst-1 (Serine/threonine-protein kinase cst-1 Serine/threonine-protein kinase cst-1 37kDa subunit Serine/threonine-protein kinase cst-1 18kDa subunit [Source:UniProtKB/Swiss-Prot;Acc:Q9NB31]) HSP 1 Score: 117.087 bits (292), Expect = 2.347e-27 Identity = 82/261 (31.42%), Postives = 136/261 (52.11%), Query Frame = 2
Query: 1442 EVIEEIDRGYYSILLKAKIKSKDKDIVLKKYTEIDLPDLNKNNVLLKELSIFQTLKSHHRFLKLFGIYKEENYFYIAMENMKGGSIKTHIK-KNKPLDEKQIAFWSKQILEGLKYLHDQEFVYRDLKTSNILIDDKNDVKLPSVSLSKYLHDYNRKPEQMGYQDNLPLRYMAPEILQQHPYGIKADVWSFGAIIVEMVTGIQPYSELNETDAIQRIIQDRTIKYNTT-AISHNLKEFIGLCLIFNPEERSSDDKLMNHSFL 2218
+++ ++ G Y + KA I + ++ K +D DL + ++KE+SI Q KS + +K +G Y + + +I ME GSI ++ + KPL E++I+ + L+GL+YLHD + ++RD+K NIL++ KL ++ L D K + P +MAPE++++ Y KAD+WS G +EM G PYS+++ AI I + S +FI CLI PEER + +L H+F+
Sbjct: 36 DIVGKLGEGSYGSVHKA-IHRESGHVLAIKKVPVDT-DLQE---IIKEISIMQQCKSKY-VVKYYGSYFKHSDLWIVMEYCGAGSISDIMRARRKPLSEQEISAVLRDTLKGLQYLHDLKKIHRDIKAGNILLNTDGIAKLADFGVAGQLTDTMAKRNTV---IGTPF-WMAPEVIEEIGYDTKADIWSLGITAIEMAEGRPPYSDIHPMRAIFMIPTKPPPTFKKPEEWSSEFNDFIRSCLIKKPEERKTALRLCEHTFI 286
BLAST of Protein kinase domain-containing protein vs. Ensembl Fly
Match: Ask1 (gene:FBgn0014006 transcript:FBtr0300256) HSP 1 Score: 125.946 bits (315), Expect = 3.464e-29 Identity = 90/265 (33.96%), Postives = 134/265 (50.57%), Query Frame = 2
Query: 1457 IDRGYYSILLKAKIKSKDKDIVLKKYTEIDLPDLNKNNV--LLKELSIFQTLKSHHRFLKLFGIYKEENYFYIAMENMKGGSIKTHIK-KNKPL--DEKQIAFWSKQILEGLKYLHDQEFVYRDLKTSNILIDDKND-VKLPSVSLSKYLHDYNRKPEQMGYQDNLPLRYMAPEILQQ--HPYGIKADVWSFGAIIVEMVTGIQPYSELNETDAIQRIIQDRTIKYNTT-AISHNLKEFIGLCLIFNPEERSSDDKLMNHSFLNE 2224
+ +G Y + A+ K I +K ++P+ N +V L +E+ + L+ H ++ G E +F I ME + GGS+ ++ K PL +E +AF+SKQILEGLKYLH+Q+ V+RD+K N+L++ + VK+ SK L N E L+YMAPE++ Q YG AD+WSFG VEM TG P+ EL A + N +S N K FI C + +R S +L+ FL +
Sbjct: 591 LGKGTYGTVYAARDKQTQVRIAIK-----EVPEKNSQDVQPLHEEIKLHSQLR-HRNIVRYLGSCSENGFFKIFMEQVPGGSLSDLLETKWGPLKDNESTMAFYSKQILEGLKYLHEQDIVHRDIKGDNVLVNTYSGVVKISDFGTSKRLARINPMTETF----TGTLQYMAPEVIDQGVRGYGPAADIWSFGCTNVEMATGKPPFIELGSAHAAMFKVGFYKKHPNIPEELSANAKNFILRCFAISVMDRPSASQLLEDPFLQD 845
BLAST of Protein kinase domain-containing protein vs. Ensembl Fly
Match: Ask1 (gene:FBgn0014006 transcript:FBtr0083819) HSP 1 Score: 125.561 bits (314), Expect = 4.050e-29 Identity = 90/265 (33.96%), Postives = 134/265 (50.57%), Query Frame = 2
Query: 1457 IDRGYYSILLKAKIKSKDKDIVLKKYTEIDLPDLNKNNV--LLKELSIFQTLKSHHRFLKLFGIYKEENYFYIAMENMKGGSIKTHIK-KNKPL--DEKQIAFWSKQILEGLKYLHDQEFVYRDLKTSNILIDDKND-VKLPSVSLSKYLHDYNRKPEQMGYQDNLPLRYMAPEILQQ--HPYGIKADVWSFGAIIVEMVTGIQPYSELNETDAIQRIIQDRTIKYNTT-AISHNLKEFIGLCLIFNPEERSSDDKLMNHSFLNE 2224
+ +G Y + A+ K I +K ++P+ N +V L +E+ + L+ H ++ G E +F I ME + GGS+ ++ K PL +E +AF+SKQILEGLKYLH+Q+ V+RD+K N+L++ + VK+ SK L N E L+YMAPE++ Q YG AD+WSFG VEM TG P+ EL A + N +S N K FI C + +R S +L+ FL +
Sbjct: 424 LGKGTYGTVYAARDKQTQVRIAIK-----EVPEKNSQDVQPLHEEIKLHSQLR-HRNIVRYLGSCSENGFFKIFMEQVPGGSLSDLLETKWGPLKDNESTMAFYSKQILEGLKYLHEQDIVHRDIKGDNVLVNTYSGVVKISDFGTSKRLARINPMTETF----TGTLQYMAPEVIDQGVRGYGPAADIWSFGCTNVEMATGKPPFIELGSAHAAMFKVGFYKKHPNIPEELSANAKNFILRCFAISVMDRPSASQLLEDPFLQD 678
BLAST of Protein kinase domain-containing protein vs. Ensembl Fly
Match: mbt (gene:FBgn0025743 transcript:FBtr0074285) HSP 1 Score: 108.227 bits (269), Expect = 5.805e-24 Identity = 74/267 (27.72%), Postives = 132/267 (49.44%), Query Frame = 2
Query: 1454 EIDRGYYSILLKAKIKSKDKDIVLKKYTEIDLPDLNKNNVLLKELSIFQTLKSHHRFLKLFGIYKEENYFYIAMENMKGGSIKTHIKKNKPLDEKQIAFWSKQILEGLKYLHDQEFVYRDLKTSNILIDDKNDVKLPSVSLSKYLHDYNRKPEQMGYQDNLPLR--------YMAPEILQQHPYGIKADVWSFGAIIVEMVTGIQPYSELNETDAIQRI--IQDRTIKYNTTAISHNLKEFIGLCLIFNPEERSSDDKLMNHSFLNE 2224
+I G + A KS + + +KK +DL + +L E+ I + H ++ + + + ++ ME ++GG++ T I + +DE+QIA KQ L+ L YLH Q ++RD+K+ +IL+ VKL + LP R +M+PE++ + PYG + D+WS G +++EMV G P+ A++RI +Q +K N +S L+ F+ L+ +P +R++ +L+ H FL +
Sbjct: 373 KIGEGSTGTVCIATDKSTGRQVAVKK---MDLRKQQRRELLFNEVVIMRDYH-HPNIVETYSSFLVNDELWVVMEYLEGGAL-TDIVTHSRMDEEQIATVCKQCLKALAYLHSQGVIHRDIKSDSILLAADGRVKLSDFGFCAQV------------SQELPKRKSLVGTPYWMSPEVISRLPYGPEVDIWSLGIMVIEMVDGEPPFFNEPPLQAMRRIRDMQPPNLK-NAHKVSPRLQSFLDRMLVRDPAQRATAAELLAHPFLRQ 621
BLAST of Protein kinase domain-containing protein vs. Ensembl Fly
Match: aPKC (gene:FBgn0261854 transcript:FBtr0303429) HSP 1 Score: 102.449 bits (254), Expect = 2.106e-22 Identity = 60/235 (25.53%), Postives = 119/235 (50.64%), Query Frame = 2
Query: 1427 NLHDVEVIEEIDRGYYSILLKAKIKSKDKDIVLKKYTEIDLPDLNKNNVLLKELSIFQTLKSHHRFLKLFGIYKEENYFYIAMENMKGGSIKTHIKKNKPLDEKQIAFWSKQILEGLKYLHDQEFVYRDLKTSNILIDDKNDVKLPSVSLSKYLHDYNRKPEQMGYQDNLPLRYMAPEILQQHPYGIKADVWSFGAIIVEMVTGIQPY--------SELNETDAIQRIIQDRTIK 2107
+L+D E+I I RG Y+ +L +++ + +K + + D + + E +F+T +H + L ++ + + +E ++GG + H+++ + L E+ F++ +I L +LH++ +YRDLK N+L+D + +KL + K + R + P Y+APEIL+ YG D W+ G ++ EM+ G P+ + N D + ++I ++TI+
Sbjct: 178 SLNDFELIRVIGRGSYAKVLMVELRRTRRIYAMKVIKKALVTDDEDIDWVQTEKHVFETASNHPFLVGLHSCFQTPSRLFFVIEFVRGGDLMYHMQRQRRLPEEHARFYAAEISLALNFLHEKGIIYRDLKLDNVLLDHEGHIKLTDYGMCK---EGIRPGDTTSTFCGTP-NYIAPEILRGEDYGFSVDWWALGVLLYEMLAGRSPFDLAGASENPDQNTEDYLFQVILEKTIR 408
BLAST of Protein kinase domain-containing protein vs. Ensembl Fly
Match: aPKC (gene:FBgn0261854 transcript:FBtr0303433) HSP 1 Score: 102.064 bits (253), Expect = 2.172e-22 Identity = 60/235 (25.53%), Postives = 119/235 (50.64%), Query Frame = 2
Query: 1427 NLHDVEVIEEIDRGYYSILLKAKIKSKDKDIVLKKYTEIDLPDLNKNNVLLKELSIFQTLKSHHRFLKLFGIYKEENYFYIAMENMKGGSIKTHIKKNKPLDEKQIAFWSKQILEGLKYLHDQEFVYRDLKTSNILIDDKNDVKLPSVSLSKYLHDYNRKPEQMGYQDNLPLRYMAPEILQQHPYGIKADVWSFGAIIVEMVTGIQPY--------SELNETDAIQRIIQDRTIK 2107
+L+D E+I I RG Y+ +L +++ + +K + + D + + E +F+T +H + L ++ + + +E ++GG + H+++ + L E+ F++ +I L +LH++ +YRDLK N+L+D + +KL + K + R + P Y+APEIL+ YG D W+ G ++ EM+ G P+ + N D + ++I ++TI+
Sbjct: 157 SLNDFELIRVIGRGSYAKVLMVELRRTRRIYAMKVIKKALVTDDEDIDWVQTEKHVFETASNHPFLVGLHSCFQTPSRLFFVIEFVRGGDLMYHMQRQRRLPEEHARFYAAEISLALNFLHEKGIIYRDLKLDNVLLDHEGHIKLTDYGMCK---EGIRPGDTTSTFCGTP-NYIAPEILRGEDYGFSVDWWALGVLLYEMLAGRSPFDLAGASENPDQNTEDYLFQVILEKTIR 387
BLAST of Protein kinase domain-containing protein vs. Ensembl Zebrafish
Match: si:ch211-1i11.3 (si:ch211-1i11.3 [Source:ZFIN;Acc:ZDB-GENE-030131-8638]) HSP 1 Score: 134.035 bits (336), Expect = 1.021e-31 Identity = 90/283 (31.80%), Postives = 149/283 (52.65%), Query Frame = 2
Query: 1391 NQHSEVKFVCIRNLHDVEVIEEIDRGYYSILLKAKIKSKDKDIVLKKYTEIDLPDLNKNNVLLKELSIFQTLKSHHRFLKLFGIYKEENYFYIAMENMKGGSIKTHIK-KNKPL--DEKQIAFWSKQILEGLKYLHDQEFVYRDLKTSNILIDDKNDV-KLPSVSLSKYLHDYNRKPEQMGYQDNLPLRYMAPEILQQHP--YGIKADVWSFGAIIVEMVTGIQPYSELNETDAIQ-RIIQDRTIKYNTTAISHNLKEFIGLCLIFNPEERSSDDKLMNHSFL 2218
+ +++++ RN + +V+ + +G Y ++ + S I +K EI D + L +E+++ + LK H ++ G E+ + I ME + GGS+ + ++ K PL +E I F++KQIL+GLKYLHD + V+RD+K N+L++ + V K+ SK L N E L+YMAPEI+ Q P YG AD+WS G I+EM TG P+ EL A ++ + +S K+FI C NP++R++ +L+ + FL
Sbjct: 618 GEEGDLEYIYERNENGDKVV--LGKGTYGVVYAGRDLSNQVRIAIK---EIPEKDSTYSQPLHEEIALHKRLK-HRNIVQYLGSVSEDGFIKIFMEEVPGGSLSSLLRSKWGPLKDNEATIVFYTKQILDGLKYLHDNQIVHRDIKGDNVLVNTYSGVLKISDFGTSKRLAGINPCTETFTGT----LQYMAPEIIDQGPRGYGKPADIWSLGCTIIEMATGKPPFHELGSPQAAMFKVGMFKIHPAVPECMSEQAKDFIMCCFEPNPDKRTTASELLKNGFL 890
BLAST of Protein kinase domain-containing protein vs. Ensembl Zebrafish
Match: si:ch211-1i11.3 (si:ch211-1i11.3 [Source:ZFIN;Acc:ZDB-GENE-030131-8638]) HSP 1 Score: 134.035 bits (336), Expect = 1.119e-31 Identity = 90/283 (31.80%), Postives = 149/283 (52.65%), Query Frame = 2
Query: 1391 NQHSEVKFVCIRNLHDVEVIEEIDRGYYSILLKAKIKSKDKDIVLKKYTEIDLPDLNKNNVLLKELSIFQTLKSHHRFLKLFGIYKEENYFYIAMENMKGGSIKTHIK-KNKPL--DEKQIAFWSKQILEGLKYLHDQEFVYRDLKTSNILIDDKNDV-KLPSVSLSKYLHDYNRKPEQMGYQDNLPLRYMAPEILQQHP--YGIKADVWSFGAIIVEMVTGIQPYSELNETDAIQ-RIIQDRTIKYNTTAISHNLKEFIGLCLIFNPEERSSDDKLMNHSFL 2218
+ +++++ RN + +V+ + +G Y ++ + S I +K EI D + L +E+++ + LK H ++ G E+ + I ME + GGS+ + ++ K PL +E I F++KQIL+GLKYLHD + V+RD+K N+L++ + V K+ SK L N E L+YMAPEI+ Q P YG AD+WS G I+EM TG P+ EL A ++ + +S K+FI C NP++R++ +L+ + FL
Sbjct: 618 GEEGDLEYIYERNENGDKVV--LGKGTYGVVYAGRDLSNQVRIAIK---EIPEKDSTYSQPLHEEIALHKRLK-HRNIVQYLGSVSEDGFIKIFMEEVPGGSLSSLLRSKWGPLKDNEATIVFYTKQILDGLKYLHDNQIVHRDIKGDNVLVNTYSGVLKISDFGTSKRLAGINPCTETFTGT----LQYMAPEIIDQGPRGYGKPADIWSLGCTIIEMATGKPPFHELGSPQAAMFKVGMFKIHPAVPECMSEQAKDFIMCCFEPNPDKRTTASELLKNGFL 890
BLAST of Protein kinase domain-containing protein vs. Ensembl Zebrafish
Match: si:ch211-1i11.3 (si:ch211-1i11.3 [Source:ZFIN;Acc:ZDB-GENE-030131-8638]) HSP 1 Score: 134.035 bits (336), Expect = 1.237e-31 Identity = 90/283 (31.80%), Postives = 149/283 (52.65%), Query Frame = 2
Query: 1391 NQHSEVKFVCIRNLHDVEVIEEIDRGYYSILLKAKIKSKDKDIVLKKYTEIDLPDLNKNNVLLKELSIFQTLKSHHRFLKLFGIYKEENYFYIAMENMKGGSIKTHIK-KNKPL--DEKQIAFWSKQILEGLKYLHDQEFVYRDLKTSNILIDDKNDV-KLPSVSLSKYLHDYNRKPEQMGYQDNLPLRYMAPEILQQHP--YGIKADVWSFGAIIVEMVTGIQPYSELNETDAIQ-RIIQDRTIKYNTTAISHNLKEFIGLCLIFNPEERSSDDKLMNHSFL 2218
+ +++++ RN + +V+ + +G Y ++ + S I +K EI D + L +E+++ + LK H ++ G E+ + I ME + GGS+ + ++ K PL +E I F++KQIL+GLKYLHD + V+RD+K N+L++ + V K+ SK L N E L+YMAPEI+ Q P YG AD+WS G I+EM TG P+ EL A ++ + +S K+FI C NP++R++ +L+ + FL
Sbjct: 467 GEEGDLEYIYERNENGDKVV--LGKGTYGVVYAGRDLSNQVRIAIK---EIPEKDSTYSQPLHEEIALHKRLK-HRNIVQYLGSVSEDGFIKIFMEEVPGGSLSSLLRSKWGPLKDNEATIVFYTKQILDGLKYLHDNQIVHRDIKGDNVLVNTYSGVLKISDFGTSKRLAGINPCTETFTGT----LQYMAPEIIDQGPRGYGKPADIWSLGCTIIEMATGKPPFHELGSPQAAMFKVGMFKIHPAVPECMSEQAKDFIMCCFEPNPDKRTTASELLKNGFL 739
BLAST of Protein kinase domain-containing protein vs. Ensembl Zebrafish
Match: map3k5 (mitogen-activated protein kinase kinase kinase 5 [Source:ZFIN;Acc:ZDB-GENE-030827-3]) HSP 1 Score: 127.872 bits (320), Expect = 1.280e-29 Identity = 87/262 (33.21%), Postives = 134/262 (51.15%), Query Frame = 2
Query: 1457 IDRGYYSILLKAKIKSKDKDIVLKKYTEIDLPDLNKNNVLLKELSIFQTLKSHHRFLKLFGIYKEENYFYIAMENMKGGSIKTHIK-KNKPL--DEKQIAFWSKQILEGLKYLHDQEFVYRDLKTSNILIDDKNDV-KLPSVSLSKYLHDYNRKPEQMGYQDNLPLRYMAPEILQQHP--YGIKADVWSFGAIIVEMVTGIQPYSELNETDAIQRIIQDRTIKYNTT-AISHNLKEFIGLCLIFNPEERSSDDKLMNHSFLN 2221
+ +G + ++ + S + +K EI D + L +E+++ + LK H ++ G E + I ME + GGS+ ++ K PL +E I F++KQIL+GLKYLHD + V+RD+K N+LI+ + V K+ SK L N E L+YMAPEI+ + P YG AD+WS G I+EM TG P+ EL E A + I ++S K FI C +P+ R++ + L+ H FL
Sbjct: 667 LGKGTFGVVYAGRDLSNQVRLAIK---EIPERDSRYSQPLHEEIALHKHLK-HKNIVQYLGSISENGFIKIFMEQVPGGSLSALLRSKWGPLKNNEPTIGFYTKQILDGLKYLHDNQIVHRDIKGDNVLINTYSGVLKISDFGTSKRLAGINPCTETFTGT----LQYMAPEIIDKGPRGYGKPADIWSLGCTIIEMATGKPPFYELGEPQAAMFKVGMFKIHPEIPDSMSSEAKAFILRCFEPDPDSRATANDLLTHEFLT 920
BLAST of Protein kinase domain-containing protein vs. Ensembl Zebrafish
Match: map3k5 (mitogen-activated protein kinase kinase kinase 5 [Source:ZFIN;Acc:ZDB-GENE-030827-3]) HSP 1 Score: 127.487 bits (319), Expect = 1.489e-29 Identity = 87/262 (33.21%), Postives = 134/262 (51.15%), Query Frame = 2
Query: 1457 IDRGYYSILLKAKIKSKDKDIVLKKYTEIDLPDLNKNNVLLKELSIFQTLKSHHRFLKLFGIYKEENYFYIAMENMKGGSIKTHIK-KNKPL--DEKQIAFWSKQILEGLKYLHDQEFVYRDLKTSNILIDDKNDV-KLPSVSLSKYLHDYNRKPEQMGYQDNLPLRYMAPEILQQHP--YGIKADVWSFGAIIVEMVTGIQPYSELNETDAIQRIIQDRTIKYNTT-AISHNLKEFIGLCLIFNPEERSSDDKLMNHSFLN 2221
+ +G + ++ + S + +K EI D + L +E+++ + LK H ++ G E + I ME + GGS+ ++ K PL +E I F++KQIL+GLKYLHD + V+RD+K N+LI+ + V K+ SK L N E L+YMAPEI+ + P YG AD+WS G I+EM TG P+ EL E A + I ++S K FI C +P+ R++ + L+ H FL
Sbjct: 675 LGKGTFGVVYAGRDLSNQVRLAIK---EIPERDSRYSQPLHEEIALHKHLK-HKNIVQYLGSISENGFIKIFMEQVPGGSLSALLRSKWGPLKNNEPTIGFYTKQILDGLKYLHDNQIVHRDIKGDNVLINTYSGVLKISDFGTSKRLAGINPCTETFTGT----LQYMAPEIIDKGPRGYGKPADIWSLGCTIIEMATGKPPFYELGEPQAAMFKVGMFKIHPEIPDSMSSEAKAFILRCFEPDPDSRATANDLLTHEFLT 928
BLAST of Protein kinase domain-containing protein vs. Ensembl Xenopus
Match: MAP3K15 (mitogen-activated protein kinase kinase kinase 5 [Source:NCBI gene;Acc:549376]) HSP 1 Score: 134.806 bits (338), Expect = 1.128e-31 Identity = 90/263 (34.22%), Postives = 135/263 (51.33%), Query Frame = 2
Query: 1457 IDRGYYSILLKAKIKSKDKDIVLKKYTEIDLPDLNKNNVLLKELSIFQTLKSHHRFLKLFGIYKEENYFYIAMENMKGGSIKTHIK-KNKPLDEKQIAFWSKQILEGLKYLHDQEFVYRDLKTSNILIDDKNDV-KLPSVSLSKYLHDYNRKPEQMGYQDNLPLRYMAPEILQQHP--YGIKADVWSFGAIIVEMVTGIQPYSELNETDAIQRIIQDRTIKYNTT-AISHNLKEFIGLCLIFNPEERSSDDKLMNHSFLNE*N 2230
+ RG Y ++ + S I +K EI D + L +E+++ + LK H ++ G E+ Y I ME + GGS+ ++ K PL E I F++KQILEGLKYLH+ + V+RD+K N+L++ + V K+ SK L N E L+YMAPEI+ + P YG AD+WS G I+EM TG P+ EL E A + I ++S + FI LC +P +R++ L+ FL + N
Sbjct: 657 LGRGTYGVVYAGRDLSNQVRIAIK---EIPEKDSRYSQPLHEEIALHKYLK-HRNIVQYLGSISEDGYIKIFMEQVPGGSLSVLLRSKWGPLKEPTIKFYTKQILEGLKYLHENQIVHRDIKGDNVLVNTYSGVLKISDFGTSKRLAGVNPCTETF----TGTLQYMAPEIIDKGPRGYGAPADIWSLGCTIIEMATGRPPFHELGEPQAAMFKVGMFKIHPEIPESLSAEARAFILLCFEPDPAKRATVTDLLRDFFLKQSN 911
BLAST of Protein kinase domain-containing protein vs. Ensembl Xenopus
Match: MAP3K15 (mitogen-activated protein kinase kinase kinase 5 [Source:NCBI gene;Acc:549376]) HSP 1 Score: 134.42 bits (337), Expect = 1.465e-31 Identity = 90/263 (34.22%), Postives = 135/263 (51.33%), Query Frame = 2
Query: 1457 IDRGYYSILLKAKIKSKDKDIVLKKYTEIDLPDLNKNNVLLKELSIFQTLKSHHRFLKLFGIYKEENYFYIAMENMKGGSIKTHIK-KNKPLDEKQIAFWSKQILEGLKYLHDQEFVYRDLKTSNILIDDKNDV-KLPSVSLSKYLHDYNRKPEQMGYQDNLPLRYMAPEILQQHP--YGIKADVWSFGAIIVEMVTGIQPYSELNETDAIQRIIQDRTIKYNTT-AISHNLKEFIGLCLIFNPEERSSDDKLMNHSFLNE*N 2230
+ RG Y ++ + S I +K EI D + L +E+++ + LK H ++ G E+ Y I ME + GGS+ ++ K PL E I F++KQILEGLKYLH+ + V+RD+K N+L++ + V K+ SK L N E L+YMAPEI+ + P YG AD+WS G I+EM TG P+ EL E A + I ++S + FI LC +P +R++ L+ FL + N
Sbjct: 649 LGRGTYGVVYAGRDLSNQVRIAIK---EIPEKDSRYSQPLHEEIALHKYLK-HRNIVQYLGSISEDGYIKIFMEQVPGGSLSVLLRSKWGPLKEPTIKFYTKQILEGLKYLHENQIVHRDIKGDNVLVNTYSGVLKISDFGTSKRLAGVNPCTETF----TGTLQYMAPEIIDKGPRGYGAPADIWSLGCTIIEMATGRPPFHELGEPQAAMFKVGMFKIHPEIPESLSAEARAFILLCFEPDPAKRATVTDLLRDFFLKQSN 903
BLAST of Protein kinase domain-containing protein vs. Ensembl Xenopus
Match: MAP3K15 (mitogen-activated protein kinase kinase kinase 5 [Source:NCBI gene;Acc:549376]) HSP 1 Score: 134.035 bits (336), Expect = 1.532e-31 Identity = 90/263 (34.22%), Postives = 135/263 (51.33%), Query Frame = 2
Query: 1457 IDRGYYSILLKAKIKSKDKDIVLKKYTEIDLPDLNKNNVLLKELSIFQTLKSHHRFLKLFGIYKEENYFYIAMENMKGGSIKTHIK-KNKPLDEKQIAFWSKQILEGLKYLHDQEFVYRDLKTSNILIDDKNDV-KLPSVSLSKYLHDYNRKPEQMGYQDNLPLRYMAPEILQQHP--YGIKADVWSFGAIIVEMVTGIQPYSELNETDAIQRIIQDRTIKYNTT-AISHNLKEFIGLCLIFNPEERSSDDKLMNHSFLNE*N 2230
+ RG Y ++ + S I +K EI D + L +E+++ + LK H ++ G E+ Y I ME + GGS+ ++ K PL E I F++KQILEGLKYLH+ + V+RD+K N+L++ + V K+ SK L N E L+YMAPEI+ + P YG AD+WS G I+EM TG P+ EL E A + I ++S + FI LC +P +R++ L+ FL + N
Sbjct: 639 LGRGTYGVVYAGRDLSNQVRIAIK---EIPEKDSRYSQPLHEEIALHKYLK-HRNIVQYLGSISEDGYIKIFMEQVPGGSLSVLLRSKWGPLKEPTIKFYTKQILEGLKYLHENQIVHRDIKGDNVLVNTYSGVLKISDFGTSKRLAGVNPCTETF----TGTLQYMAPEIIDKGPRGYGAPADIWSLGCTIIEMATGRPPFHELGEPQAAMFKVGMFKIHPEIPESLSAEARAFILLCFEPDPAKRATVTDLLRDFFLKQSN 893
BLAST of Protein kinase domain-containing protein vs. Ensembl Xenopus
Match: MAP3K15 (mitogen-activated protein kinase kinase kinase 5 [Source:NCBI gene;Acc:549376]) HSP 1 Score: 134.035 bits (336), Expect = 1.717e-31 Identity = 90/263 (34.22%), Postives = 135/263 (51.33%), Query Frame = 2
Query: 1457 IDRGYYSILLKAKIKSKDKDIVLKKYTEIDLPDLNKNNVLLKELSIFQTLKSHHRFLKLFGIYKEENYFYIAMENMKGGSIKTHIK-KNKPLDEKQIAFWSKQILEGLKYLHDQEFVYRDLKTSNILIDDKNDV-KLPSVSLSKYLHDYNRKPEQMGYQDNLPLRYMAPEILQQHP--YGIKADVWSFGAIIVEMVTGIQPYSELNETDAIQRIIQDRTIKYNTT-AISHNLKEFIGLCLIFNPEERSSDDKLMNHSFLNE*N 2230
+ RG Y ++ + S I +K EI D + L +E+++ + LK H ++ G E+ Y I ME + GGS+ ++ K PL E I F++KQILEGLKYLH+ + V+RD+K N+L++ + V K+ SK L N E L+YMAPEI+ + P YG AD+WS G I+EM TG P+ EL E A + I ++S + FI LC +P +R++ L+ FL + N
Sbjct: 657 LGRGTYGVVYAGRDLSNQVRIAIK---EIPEKDSRYSQPLHEEIALHKYLK-HRNIVQYLGSISEDGYIKIFMEQVPGGSLSVLLRSKWGPLKEPTIKFYTKQILEGLKYLHENQIVHRDIKGDNVLVNTYSGVLKISDFGTSKRLAGVNPCTETF----TGTLQYMAPEIIDKGPRGYGAPADIWSLGCTIIEMATGRPPFHELGEPQAAMFKVGMFKIHPEIPESLSAEARAFILLCFEPDPAKRATVTDLLRDFFLKQSN 911
BLAST of Protein kinase domain-containing protein vs. Ensembl Xenopus
Match: MAP3K15 (mitogen-activated protein kinase kinase kinase 5 [Source:NCBI gene;Acc:549376]) HSP 1 Score: 134.035 bits (336), Expect = 1.721e-31 Identity = 90/263 (34.22%), Postives = 135/263 (51.33%), Query Frame = 2
Query: 1457 IDRGYYSILLKAKIKSKDKDIVLKKYTEIDLPDLNKNNVLLKELSIFQTLKSHHRFLKLFGIYKEENYFYIAMENMKGGSIKTHIK-KNKPLDEKQIAFWSKQILEGLKYLHDQEFVYRDLKTSNILIDDKNDV-KLPSVSLSKYLHDYNRKPEQMGYQDNLPLRYMAPEILQQHP--YGIKADVWSFGAIIVEMVTGIQPYSELNETDAIQRIIQDRTIKYNTT-AISHNLKEFIGLCLIFNPEERSSDDKLMNHSFLNE*N 2230
+ RG Y ++ + S I +K EI D + L +E+++ + LK H ++ G E+ Y I ME + GGS+ ++ K PL E I F++KQILEGLKYLH+ + V+RD+K N+L++ + V K+ SK L N E L+YMAPEI+ + P YG AD+WS G I+EM TG P+ EL E A + I ++S + FI LC +P +R++ L+ FL + N
Sbjct: 649 LGRGTYGVVYAGRDLSNQVRIAIK---EIPEKDSRYSQPLHEEIALHKYLK-HRNIVQYLGSISEDGYIKIFMEQVPGGSLSVLLRSKWGPLKEPTIKFYTKQILEGLKYLHENQIVHRDIKGDNVLVNTYSGVLKISDFGTSKRLAGVNPCTETF----TGTLQYMAPEIIDKGPRGYGAPADIWSLGCTIIEMATGRPPFHELGEPQAAMFKVGMFKIHPEIPESLSAEARAFILLCFEPDPAKRATVTDLLRDFFLKQSN 903
BLAST of Protein kinase domain-containing protein vs. Ensembl Mouse
Match: Map3k15 (mitogen-activated protein kinase kinase kinase 15 [Source:MGI Symbol;Acc:MGI:2448588]) HSP 1 Score: 132.494 bits (332), Expect = 4.286e-31 Identity = 89/263 (33.84%), Postives = 133/263 (50.57%), Query Frame = 2
Query: 1457 IDRGYYSILLKAKIKSKDKDIVLKKYTEIDLPDLNKNNVLLKELSIFQTLKSHHRFLKLFGIYKEENYFYIAMENMKGGSIKTHIK-KNKPLDEKQIAFWSKQILEGLKYLHDQEFVYRDLKTSNILIDDKND-VKLPSVSLSKYLHDYNRKPEQMGYQDNLPLRYMAPEILQQHP--YGIKADVWSFGAIIVEMVTGIQPYSELNETDAIQRIIQDRTIKYNTT-AISHNLKEFIGLCLIFNPEERSSDDKLMNHSFLNE*N 2230
+ +G Y I+ + S I +K EI D+ + L +E+++ + LK H ++ G E Y I ME + GGS+ ++ K P+ E I F++KQILEGLKYLH+ + V+RD+K N+L++ + VK+ SK L N E L+YMAPEI+ Q P YG AD+WS G I+EM T P+ EL E A + I A+S + FI C +P++R + L+ FL + N
Sbjct: 662 LGKGSYGIVYAGRDLSNQVRIAIK---EIPERDIRYSQPLHEEIALHKYLK-HRNIVQYLGSVSENGYIKIFMEQVPGGSLSALLRSKWGPMKEPTIKFYTKQILEGLKYLHENQIVHRDIKGDNVLVNTYSGVVKISDFGTSKRLAGINPCTETF----TGTLQYMAPEIIDQGPRGYGAPADIWSLGCTIIEMATSRPPFHELGEPQAAMFKVGMFKIHPEIPEALSAEARAFILSCFEPDPQKRVTAADLLQEGFLRQVN 916
BLAST of Protein kinase domain-containing protein vs. Ensembl Mouse
Match: Map3k5 (mitogen-activated protein kinase kinase kinase 5 [Source:MGI Symbol;Acc:MGI:1346876]) HSP 1 Score: 128.257 bits (321), Expect = 8.631e-30 Identity = 89/261 (34.10%), Postives = 136/261 (52.11%), Query Frame = 2
Query: 1457 IDRGYYSILLKAKIKSKDKDIVLKKYTEIDLPDLNKNNVLLKELSIFQTLKSHHRFLKLFGIYKEENYFYIAMENMKGGSIKTHIK-KNKPL--DEKQIAFWSKQILEGLKYLHDQEFVYRDLKTSNILIDDKNDV-KLPSVSLSKYLHDYNRKPEQMGYQDNLPLRYMAPEILQQHP--YGIKADVWSFGAIIVEMVTGIQPYSELNETDAIQ-RIIQDRTIKYNTTAISHNLKEFIGLCLIFNPEERSSDDKLMNHSFL 2218
+ +G Y I+ + S I +K EI D + L +E+++ + LK H ++ G + E + I ME + GGS+ ++ K PL +E+ I F++KQILEGLKYLHD + V+RD+K N+LI+ + V K+ SK L N E L+YMAPEI+ + P YG AD+WS G I+EM TG P+ EL E A ++ + ++S K FI C +P++R+ + L+ FL
Sbjct: 685 LGKGTYGIVYAGRDLSNQVRIAIK---EIPERDSRYSQPLHEEIALHKHLK-HKNIVQYLGSFSENGFIKIFMEQVPGGSLSALLRSKWGPLKDNEQTIGFYTKQILEGLKYLHDNQIVHRDIKGDNVLINTYSGVLKISDFGTSKRLAGINPCTETF----TGTLQYMAPEIIDKGPRGYGKAADIWSLGCTIIEMATGKPPFYELGEPQAAMFKVGMFKVHPEIPESMSAEAKAFILKCFEPDPDKRACANDLLIDEFL 937
BLAST of Protein kinase domain-containing protein vs. Ensembl Mouse
Match: Map3k5 (mitogen-activated protein kinase kinase kinase 5 [Source:MGI Symbol;Acc:MGI:1346876]) HSP 1 Score: 128.257 bits (321), Expect = 8.661e-30 Identity = 89/261 (34.10%), Postives = 136/261 (52.11%), Query Frame = 2
Query: 1457 IDRGYYSILLKAKIKSKDKDIVLKKYTEIDLPDLNKNNVLLKELSIFQTLKSHHRFLKLFGIYKEENYFYIAMENMKGGSIKTHIK-KNKPL--DEKQIAFWSKQILEGLKYLHDQEFVYRDLKTSNILIDDKNDV-KLPSVSLSKYLHDYNRKPEQMGYQDNLPLRYMAPEILQQHP--YGIKADVWSFGAIIVEMVTGIQPYSELNETDAIQ-RIIQDRTIKYNTTAISHNLKEFIGLCLIFNPEERSSDDKLMNHSFL 2218
+ +G Y I+ + S I +K EI D + L +E+++ + LK H ++ G + E + I ME + GGS+ ++ K PL +E+ I F++KQILEGLKYLHD + V+RD+K N+LI+ + V K+ SK L N E L+YMAPEI+ + P YG AD+WS G I+EM TG P+ EL E A ++ + ++S K FI C +P++R+ + L+ FL
Sbjct: 693 LGKGTYGIVYAGRDLSNQVRIAIK---EIPERDSRYSQPLHEEIALHKHLK-HKNIVQYLGSFSENGFIKIFMEQVPGGSLSALLRSKWGPLKDNEQTIGFYTKQILEGLKYLHDNQIVHRDIKGDNVLINTYSGVLKISDFGTSKRLAGINPCTETF----TGTLQYMAPEIIDKGPRGYGKAADIWSLGCTIIEMATGKPPFYELGEPQAAMFKVGMFKVHPEIPESMSAEAKAFILKCFEPDPDKRACANDLLIDEFL 945
BLAST of Protein kinase domain-containing protein vs. Ensembl Mouse
Match: Stk4 (serine/threonine kinase 4 [Source:MGI Symbol;Acc:MGI:1929004]) HSP 1 Score: 120.939 bits (302), Expect = 2.027e-28 Identity = 81/262 (30.92%), Postives = 137/262 (52.29%), Query Frame = 2
Query: 1442 EVIEEIDRGYYSILLKAKIKSKDKDIVLKKY-TEIDLPDLNKNNVLLKELSIFQTLKSHHRFLKLFGIYKEENYFYIAMENMKGGSIKTHIK-KNKPLDEKQIAFWSKQILEGLKYLHDQEFVYRDLKTSNILIDDKNDVKLPSVSLSKYLHDYNRKPEQMGYQDNLPLRYMAPEILQQHPYGIKADVWSFGAIIVEMVTGIQPYSELNETDAIQRIIQDRTIKYNTTAI-SHNLKEFIGLCLIFNPEERSSDDKLMNHSFL 2218
+V+E++ G Y + KA K + + +K+ E DL ++ +KE+SI Q S H +K +G Y + +I ME GS+ I+ +NK L E +IA + L+GL+YLH ++RD+K NIL++ + KL ++ L D K + P +MAPE++Q+ Y AD+WS G +EM G PY++++ AI I + + + S N +F+ CL+ +PE+R++ +L+ H F+
Sbjct: 31 DVLEKLGEGSYGSVYKAIHKETGQIVAIKQVPVESDLQEI------IKEISIMQQCDSPH-VVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILQSTLKGLEYLHFMRKIHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMAKRNTV---IGTPF-WMAPEVIQEIGYNCVADIWSLGITAIEMAEGKPPYADIHPMRAIFMIPTNPPPTFRKPELWSDNFMDFVKQCLVKSPEQRATATQLLQHPFV 281
BLAST of Protein kinase domain-containing protein vs. Ensembl Mouse
Match: Stk3 (serine/threonine kinase 3 [Source:MGI Symbol;Acc:MGI:1928487]) HSP 1 Score: 120.168 bits (300), Expect = 4.539e-28 Identity = 83/272 (30.51%), Postives = 141/272 (51.84%), Query Frame = 2
Query: 1442 EVIEEIDRGYYSILLKAKIKSKDKDIVLKKY-TEIDLPDLNKNNVLLKELSIFQTLKSHHRFLKLFGIYKEENYFYIAMENMKGGSIKTHIK-KNKPLDEKQIAFWSKQILEGLKYLHDQEFVYRDLKTSNILIDDKNDVKLPSVSLSKYLHDYNRKPEQMGYQDNLPLRYMAPEILQQHPYGIKADVWSFGAIIVEMVTGIQPYSELNETDAIQRIIQDRTIKYNTTAI-SHNLKEFIGLCLIFNPEERSSDDKLMNHSFLNE*NVKEFNI 2248
+V+E++ G Y + KA K + + +K+ E DL ++ +KE+SI Q S + +K +G Y + +I ME GS+ I+ +NK L E +IA K L+GL+YLH ++RD+K NIL++ + KL ++ L D K + P +MAPE++Q+ Y AD+WS G +EM G PY++++ AI I + + + S + +F+ CL+ +PE+R++ +L+ H F+ N K +I
Sbjct: 26 DVLEKLGEGSYGSVFKAIHKESGQVVAIKQVPVESDLQEI------IKEISIMQQCDSPY-VVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILKSTLKGLEYLHFMRKIHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMAKRNTV---IGTPF-WMAPEVIQEIGYNCVADIWSLGITSIEMAEGKPPYADIHPMRAIFMIPTNPPPTFRKPELWSDDFTDFVKKCLVKSPEQRATATQLLQHPFIK--NAKPVSI 284
BLAST of Protein kinase domain-containing protein vs. UniProt/SwissProt
Match: sp|Q6ZN16|M3K15_HUMAN (Mitogen-activated protein kinase kinase kinase 15 OS=Homo sapiens OX=9606 GN=MAP3K15 PE=1 SV=2) HSP 1 Score: 132.494 bits (332), Expect = 2.894e-30 Identity = 89/263 (33.84%), Postives = 133/263 (50.57%), Query Frame = 2
Query: 1457 IDRGYYSILLKAKIKSKDKDIVLKKYTEIDLPDLNKNNVLLKELSIFQTLKSHHRFLKLFGIYKEENYFYIAMENMKGGSIKTHIK-KNKPLDEKQIAFWSKQILEGLKYLHDQEFVYRDLKTSNILIDDKND-VKLPSVSLSKYLHDYNRKPEQMGYQDNLPLRYMAPEILQQHP--YGIKADVWSFGAIIVEMVTGIQPYSELNETDAIQRIIQDRTIKYNTT-AISHNLKEFIGLCLIFNPEERSSDDKLMNHSFLNE*N 2230
+ +G Y I+ + S I +K EI D + L +E+++ + LK H ++ G E Y I ME + GGS+ ++ K P+ E I F++KQILEGLKYLH+ + V+RD+K N+L++ + VK+ SK L N E L+YMAPEI+ Q P YG AD+WS G I+EM T P+ EL E A + I A+S + FI C +P +R++ +L+ FL + N
Sbjct: 658 LGKGTYGIVYAGRDLSNQVRIAIK---EIPERDSRYSQPLHEEIALHKYLK-HRNIVQYLGSVSENGYIKIFMEQVPGGSLSALLRSKWGPMKEPTIKFYTKQILEGLKYLHENQIVHRDIKGDNVLVNTYSGVVKISDFGTSKRLAGVNPCTETF----TGTLQYMAPEIIDQGPRGYGAPADIWSLGCTIIEMATSKPPFHELGEPQAAMFKVGMFKIHPEIPEALSAEARAFILSCFEPDPHKRATTAELLREGFLRQVN 912
BLAST of Protein kinase domain-containing protein vs. UniProt/SwissProt
Match: sp|A2AQW0|M3K15_MOUSE (Mitogen-activated protein kinase kinase kinase 15 OS=Mus musculus OX=10090 GN=Map3k15 PE=1 SV=1) HSP 1 Score: 132.494 bits (332), Expect = 2.998e-30 Identity = 89/263 (33.84%), Postives = 133/263 (50.57%), Query Frame = 2
Query: 1457 IDRGYYSILLKAKIKSKDKDIVLKKYTEIDLPDLNKNNVLLKELSIFQTLKSHHRFLKLFGIYKEENYFYIAMENMKGGSIKTHIK-KNKPLDEKQIAFWSKQILEGLKYLHDQEFVYRDLKTSNILIDDKND-VKLPSVSLSKYLHDYNRKPEQMGYQDNLPLRYMAPEILQQHP--YGIKADVWSFGAIIVEMVTGIQPYSELNETDAIQRIIQDRTIKYNTT-AISHNLKEFIGLCLIFNPEERSSDDKLMNHSFLNE*N 2230
+ +G Y I+ + S I +K EI D+ + L +E+++ + LK H ++ G E Y I ME + GGS+ ++ K P+ E I F++KQILEGLKYLH+ + V+RD+K N+L++ + VK+ SK L N E L+YMAPEI+ Q P YG AD+WS G I+EM T P+ EL E A + I A+S + FI C +P++R + L+ FL + N
Sbjct: 662 LGKGSYGIVYAGRDLSNQVRIAIK---EIPERDIRYSQPLHEEIALHKYLK-HRNIVQYLGSVSENGYIKIFMEQVPGGSLSALLRSKWGPMKEPTIKFYTKQILEGLKYLHENQIVHRDIKGDNVLVNTYSGVVKISDFGTSKRLAGINPCTETF----TGTLQYMAPEIIDQGPRGYGAPADIWSLGCTIIEMATSRPPFHELGEPQAAMFKVGMFKIHPEIPEALSAEARAFILSCFEPDPQKRVTAADLLQEGFLRQVN 916
BLAST of Protein kinase domain-containing protein vs. UniProt/SwissProt
Match: sp|Q99683|M3K5_HUMAN (Mitogen-activated protein kinase kinase kinase 5 OS=Homo sapiens OX=9606 GN=MAP3K5 PE=1 SV=1) HSP 1 Score: 128.257 bits (321), Expect = 5.939e-29 Identity = 89/261 (34.10%), Postives = 136/261 (52.11%), Query Frame = 2
Query: 1457 IDRGYYSILLKAKIKSKDKDIVLKKYTEIDLPDLNKNNVLLKELSIFQTLKSHHRFLKLFGIYKEENYFYIAMENMKGGSIKTHIK-KNKPL--DEKQIAFWSKQILEGLKYLHDQEFVYRDLKTSNILIDDKNDV-KLPSVSLSKYLHDYNRKPEQMGYQDNLPLRYMAPEILQQHP--YGIKADVWSFGAIIVEMVTGIQPYSELNETDAIQ-RIIQDRTIKYNTTAISHNLKEFIGLCLIFNPEERSSDDKLMNHSFL 2218
+ +G Y I+ + S I +K EI D + L +E+++ + LK H ++ G + E + I ME + GGS+ ++ K PL +E+ I F++KQILEGLKYLHD + V+RD+K N+LI+ + V K+ SK L N E L+YMAPEI+ + P YG AD+WS G I+EM TG P+ EL E A ++ + ++S K FI C +P++R+ + L+ FL
Sbjct: 686 LGKGTYGIVYAGRDLSNQVRIAIK---EIPERDSRYSQPLHEEIALHKHLK-HKNIVQYLGSFSENGFIKIFMEQVPGGSLSALLRSKWGPLKDNEQTIGFYTKQILEGLKYLHDNQIVHRDIKGDNVLINTYSGVLKISDFGTSKRLAGINPCTETF----TGTLQYMAPEIIDKGPRGYGKAADIWSLGCTIIEMATGKPPFYELGEPQAAMFKVGMFKVHPEIPESMSAEAKAFILKCFEPDPDKRACANDLLVDEFL 938
BLAST of Protein kinase domain-containing protein vs. UniProt/SwissProt
Match: sp|O35099|M3K5_MOUSE (Mitogen-activated protein kinase kinase kinase 5 OS=Mus musculus OX=10090 GN=Map3k5 PE=1 SV=3) HSP 1 Score: 128.257 bits (321), Expect = 6.058e-29 Identity = 89/261 (34.10%), Postives = 136/261 (52.11%), Query Frame = 2
Query: 1457 IDRGYYSILLKAKIKSKDKDIVLKKYTEIDLPDLNKNNVLLKELSIFQTLKSHHRFLKLFGIYKEENYFYIAMENMKGGSIKTHIK-KNKPL--DEKQIAFWSKQILEGLKYLHDQEFVYRDLKTSNILIDDKNDV-KLPSVSLSKYLHDYNRKPEQMGYQDNLPLRYMAPEILQQHP--YGIKADVWSFGAIIVEMVTGIQPYSELNETDAIQ-RIIQDRTIKYNTTAISHNLKEFIGLCLIFNPEERSSDDKLMNHSFL 2218
+ +G Y I+ + S I +K EI D + L +E+++ + LK H ++ G + E + I ME + GGS+ ++ K PL +E+ I F++KQILEGLKYLHD + V+RD+K N+LI+ + V K+ SK L N E L+YMAPEI+ + P YG AD+WS G I+EM TG P+ EL E A ++ + ++S K FI C +P++R+ + L+ FL
Sbjct: 693 LGKGTYGIVYAGRDLSNQVRIAIK---EIPERDSRYSQPLHEEIALHKHLK-HKNIVQYLGSFSENGFIKIFMEQVPGGSLSALLRSKWGPLKDNEQTIGFYTKQILEGLKYLHDNQIVHRDIKGDNVLINTYSGVLKISDFGTSKRLAGINPCTETF----TGTLQYMAPEIIDKGPRGYGKAADIWSLGCTIIEMATGKPPFYELGEPQAAMFKVGMFKVHPEIPESMSAEAKAFILKCFEPDPDKRACANDLLIDEFL 945
BLAST of Protein kinase domain-containing protein vs. UniProt/SwissProt
Match: sp|Q6PA14|STK4_XENLA (Serine/threonine-protein kinase 4 OS=Xenopus laevis OX=8355 GN=stk4 PE=2 SV=1) HSP 1 Score: 124.79 bits (312), Expect = 6.731e-29 Identity = 85/262 (32.44%), Postives = 137/262 (52.29%), Query Frame = 2
Query: 1442 EVIEEIDRGYYSILLKAKIKSKDKDIVLKKY-TEIDLPDLNKNNVLLKELSIFQTLKSHHRFLKLFGIYKEENYFYIAMENMKGGSIKTHIK-KNKPLDEKQIAFWSKQILEGLKYLHDQEFVYRDLKTSNILIDDKNDVKLPSVSLSKYLHDYNRKPEQMGYQDNLPLRYMAPEILQQHPYGIKADVWSFGAIIVEMVTGIQPYSELNETDAIQRIIQDRTIKYNTTAI-SHNLKEFIGLCLIFNPEERSSDDKLMNHSFL 2218
+V+E++ G Y + KA K + + +K+ E DL ++ +KE+SI Q S H +K +G Y + +I ME GGS+ I+ + + L+E +IA + L+GL+YLH ++RD+K NIL+ + KL ++ L D K + P +MAPE++Q+ Y AD+WS G +EM G PY+E++ AI I + + + S + +FI LCL+ NPE RSS +L+ H F+
Sbjct: 31 DVLEKLGEGSYGSVYKASHKETSQIVAIKQIPVESDLQEI------IKEISIMQQCDSPH-VVKYYGSYFKNTDLWIVMEFCGGGSVSDIIRLRKQTLNEDEIATILQSTLKGLEYLHFMRKIHRDIKAGNILLSCEGTAKLADFGVAGQLTDTMAKRNTV---IGTPF-WMAPEVIQEIGYNCVADIWSLGITAIEMAEGKPPYAEIHPMRAIFMIPSNPPPTFRKPELWSKDFVDFINLCLVKNPELRSSATELLQHPFI 281
BLAST of Protein kinase domain-containing protein vs. TrEMBL
Match: K0KR26 (Protein kinase domain-containing protein OS=Wickerhamomyces ciferrii (strain F-60-10 / ATCC 14091 / CBS 111 / JCM 3599 / NBRC 0793 / NRRL Y-1031) OX=1206466 GN=BN7_5169 PE=4 SV=1) HSP 1 Score: 146.747 bits (369), Expect = 2.098e-32 Identity = 96/265 (36.23%), Postives = 139/265 (52.45%), Query Frame = 2
Query: 1430 LHDVEVIEEIDRGYYSILLKAKIKSKDKDIVLKKYTEIDLPDLNKNNVLLKELSIFQTLKSHHRFLKLFGIYKEENYFYIAMENMKGGSIKTHIKKNKPLDEKQIAFWSKQILEGLKYLHDQEFVYRDLKTSNILIDDKNDVKLPSVSLSKYLHDYNRKPEQMGYQDNLPLRYMAPEILQQHPYGIKADVWSFGAIIVEMVTGIQPYSELNETDAIQRIIQDRTIKYNTTAISHNLKEFIGLCLIFNPEERSSDDKLMNHSFLNE 2224
L E E I RG ++ + +A K + ++ +K EI + D + L+ E+ + + LK H +K G K + I +E GGS++T KK PL EKQ+A + Q+LEGLKYLH Q V+RD+K +NIL+ K D+KL +S + K + N +MAPEI+ +D+WS GA IVE++TG YS LNE A+ I+ D + T IS K+FI C P ER S +L NH +L +
Sbjct: 151 LSSYEFKETIGRGAFANVYRAINKITNDEVAIK---EIFIEDDDNILELMCEIDLLKILK-HKNIVKYHGFIKNDKKLLIFLEYCSGGSLRTLYKKQGPLSEKQVAKYLVQVLEGLKYLHSQGVVHRDVKAANILLTSKGDIKLTDFGVSTKVSSNTIKTYSIAGTPN----WMAPEIISMDGTSTASDIWSLGATIVELLTGEPLYSHLNEMAALHAIVTDDSPPI-PTFISELCKDFIMKCFAKQPNERISAKELFNHPWLTK 406
BLAST of Protein kinase domain-containing protein vs. TrEMBL
Match: A8I1H8 (Predicted protein (Fragment) OS=Chlamydomonas reinhardtii OX=3055 GN=CHLREDRAFT_98709 PE=3 SV=1) HSP 1 Score: 137.117 bits (344), Expect = 2.425e-32 Identity = 76/269 (28.25%), Postives = 143/269 (53.16%), Query Frame = 2
Query: 1451 EEIDRGYYSILLKAKIKSKDKDIVLKKYTEIDLPDLNKNN--------VLLKELSIFQTLKSHHRFLKLFGIYKEENYFYIAMENMKGGSIKTHIKKNKPLDEKQIAFWSKQILEGLKYLHDQEFVYRDLKTSNILIDDKNDVKLPSVSLSKYLHDYNRKPEQMGYQDNLPLR----YMAPEILQQHPYGIKADVWSFGAIIVEMVTGIQPYSELNETDAIQ-RIIQDRTIKYNTTAISHNLKEFIGLCLIFNPEERSSDDKLMNHSFL 2218
+I +G + + + + + ++I +K ++ LP N N+ L E+++ ++L+ H ++ G + + I +E + GG I + + + PL E+ + ++KQIL GL+YLH Q+ ++RD+K +NIL+D VKL SK + D +G + +R +MAPE+++Q +G AD+WS G +++EM TG P++ ++ A+ + + + ++SH K+FI LC P ER + +L+ H +L
Sbjct: 12 RQIGQGAFGTVYQGLVHATGQEIAVK---QVQLPRDNANSGKVSEHIRSLESEVAVLRSLR-HENIVRYLGTERTSEHLNIFLEYVAGGPISSKLAQFGPLREETVRVYTKQILRGLEYLHKQKVMHRDIKGANILVDSNGVVKLADFGASKKIEDL----ATIG-GGSRSIRGTANWMAPEVIKQSGHGRAADIWSLGCVVIEMATGRAPWANFSDPYAVMYHVAATKELPAMPDSLSHAAKDFITLCFNRVPRERPNATRLLQHPWL 271
BLAST of Protein kinase domain-containing protein vs. TrEMBL
Match: A0BC86 (Protein kinase domain-containing protein OS=Paramecium tetraurelia OX=5888 GN=GSPATT00004247001 PE=3 SV=1) HSP 1 Score: 140.584 bits (353), Expect = 8.776e-32 Identity = 78/217 (35.94%), Postives = 121/217 (55.76%), Query Frame = 2
Query: 1574 LLKELSIFQTLKSHHRFLKLFGIYKEENYFYIAMENMKGGSIKTHIKKNKPLDEKQIAFWSKQILEGLKYLHDQEFVYRDLKTSNILIDDKNDVKLPSVSLSKYLHDYNRKPEQMGYQDNLPLRYMAPEILQQHPYGIKADVWSFGAIIVEMVTGIQPYSELNETDAIQRIIQDRTIKYNTTA--ISHNLKEFIGLCLIFNPEERSSDDKLMNHSFL 2218
L KE+ + L+ H ++ G ++ + I +E + GGS+++ +++ E I + +QIL GL YLH + ++RD+K NILID+ KL SK L D+ + +G P YMAPE++ Q YG KAD+WS G I+EM TG+ P+SEL + AI I T + IS + F+ LCL +P++R++ D+L+NH FL
Sbjct: 109 LQKEIQMLSKLQ-HPNIVRYLGCEQKNQFINIFLEYVSGGSVQSMLERFGCFKESLIKTYLRQILLGLSYLHAKNVIHRDIKGGNILIDNSGKCKLADFGSSKQLSDFAH--DTLGSICGTP-NYMAPEVINQEQYGKKADIWSLGCTIIEMATGLPPFSELKDAIAIMVRIGKSTKPPSIPPQLISAESRHFVSLCLQIDPKKRATVDELLNHPFL 321
BLAST of Protein kinase domain-containing protein vs. TrEMBL
Match: Q233Z3 (Cyclin-dependent kinase-like Serine/Threonine kinase family protein OS=Tetrahymena thermophila (strain SB210) OX=312017 GN=TTHERM_00107120 PE=4 SV=2) HSP 1 Score: 144.436 bits (363), Expect = 1.505e-31 Identity = 110/340 (32.35%), Postives = 166/340 (48.82%), Query Frame = 2
Query: 1253 EFESSDMVSTLKSNLANNVNSSPDNYALFYYNEY--LDDTKLLF-------DYGINQHSEVKFVCIRNLHDVEVIEEIDRGYYSILLKAKIKSKDKDIVLKKYTEIDLPDLNKNN----VLLKELSIFQTLKSHHRFLKLFGIYKEENYFYIAMENMKGGSIKTHIKKNKPLDEKQIAFWSKQILEGLKYLHDQEFVYRDLKTSNILIDDKNDVKLPSVSLSKYLHDYNRKPEQMGYQ----DNLPLRYMAPEILQQHPYGIKADVWSFGAIIVEMVTGIQPYSELNETDAIQRIIQDRTIKYNTTAISHNLKEFIGLCLIFNPEERSSDDKLMNHSFLN 2221
+F ++ S L+SN N +NS N LF N+ L + K L DY N+H ++ HDVE+ E + G Y + K IK K I +K+ ++ L D NK L+E+++ L+ H +K + EE+ I ME M GGS+ + ++K +E I + KQI+ GL YLH Q V+RD+K +NIL D VKL ++Y D P G + L +MAPE+L Q +G K+D+WS G ++EM TG P+ + + I++ +S K+FI C F+ +ER + D L+ H FLN
Sbjct: 877 KFPQFNLQSQLQSNGQNILNSINQNNNLFSLNQMSTLLNIKTLSIKKAISNDYS-NRHDDIMITGTNPFHDVELRELLGEGAYGKVYKGFIKKTGKFIAVKQL-KLGLKDNNKLQEKLEQYLQEIALLNHLE-HPNIVKYYDCKHEEDNILIYMEQMPGGSLSSMLEKFGRFEEALIKKFVKQIISGLAYLHSQGIVHRDIKGANILTDGNGTVKLADFGAARY-RDTICLPTADGSEFCNSIKGSLYWMAPELLNQESHGRKSDIWSLGCTMIEMATGKHPWPDCRTFPQLALIVKTNQCPPIPEHLSDECKDFIRQCCTFDKKERPTADVLLKHPFLN 1212
BLAST of Protein kinase domain-containing protein vs. TrEMBL
Match: T1EDA5 (Protein kinase domain-containing protein OS=Helobdella robusta OX=6412 GN=20194557 PE=4 SV=1) HSP 1 Score: 135.191 bits (339), Expect = 1.545e-31 Identity = 75/219 (34.25%), Postives = 120/219 (54.79%), Query Frame = 2
Query: 1568 NVLLKELSIFQTLKSHHRFLKLFGIYKEENYFYIAMENMKGGSIKTHIKKNKPLDEKQIAFWSKQILEGLKYLHDQEFVYRDLKTSNILIDDKNDVKLPSVSLSKYLHDYNRKPEQMGYQDNLPLRYMAPEILQQHPYGIKADVWSFGAIIVEMVTGIQPYSELNETDAIQRIIQDRTIKYNTT-AISHNLKEFIGLCLIFNPEERSSDDKLMNHSFLN 2221
+ L +E++I + H ++ FG + F I ME M GGS+K IK+ PL E+ ++KQ+L GL+YLH + V+RD+K +NIL D++ +VKL SK L + Q + YM+PE+L + YG K D+WS G +VEM+TG P+ +L AI +I+ Y+ ++S ++F+ C + E R + +L+ HSF+
Sbjct: 50 SALREEINILKEGVKHPHIVQYFGCQDDGVVFSILMEYMPGGSVKDQIKQYGPLTERNTISYTKQVLLGLEYLHKKSIVHRDVKGANILRDNEGNVKLSDFGASKRLQTISNSIMQT---QTGTIYYMSPELLDGNGYGRKTDIWSLGCSVVEMLTGHPPWHQLENFAAIFKIVTSDEPGYSLPDSVSKQARDFVSECFTRSLERRPTSSQLLYHSFVT 265
BLAST of Protein kinase domain-containing protein vs. Ensembl Cavefish
Match: si:ch211-1i11.3 (mitogen-activated protein kinase kinase kinase 5-like [Source:NCBI gene;Acc:103038360]) HSP 1 Score: 134.035 bits (336), Expect = 1.068e-31 Identity = 89/261 (34.10%), Postives = 135/261 (51.72%), Query Frame = 2
Query: 1457 IDRGYYSILLKAKIKSKDKDIVLKKYTEIDLPDLNKNNVLLKELSIFQTLKSHHRFLKLFGIYKEENYFYIAMENMKGGSIKTHIKKN-KPL--DEKQIAFWSKQILEGLKYLHDQEFVYRDLKTSNILIDDKNDV-KLPSVSLSKYLHDYNRKPEQMGYQDNLPLRYMAPEILQQHP--YGIKADVWSFGAIIVEMVTGIQPYSELNETDAIQRIIQDRTIKYNTT-AISHNLKEFIGLCLIFNPEERSSDDKLMNHSFL 2218
+ RG Y ++ + S I +K EI D + L +E+++ + LK H ++ G E + I ME + GGS+ + ++ PL +E I F++KQILEGLKYLHD + V+RD+K N+LI+ + V K+ SK L N E L+YMAPEI+ Q P YG AD+WS G I+EM TG P+ EL A + I N ++S K + C NP++R++ +L+ ++FL
Sbjct: 636 LGRGTYGVVYAGRDLSNQVRIAIK---EIPEKDSTYSQPLHEEIALHKRLK-HRNIVQYLGSVSEGGFIKIFMEEVPGGSLSSLLRSQWGPLKDNEPTIVFYTKQILEGLKYLHDNQIVHRDIKGDNVLINTYSGVLKISDFGTSKRLAGINPCTETFTGT----LQYMAPEIIDQGPRGYGKPADIWSLGCTIIEMATGKPPFHELGSPQAAMFKVGMFKIHPNVPESMSEEAKACLMCCFESNPDKRATASELLKNAFL 888
BLAST of Protein kinase domain-containing protein vs. Ensembl Cavefish
Match: map3k5 (mitogen-activated protein kinase kinase kinase 5 [Source:NCBI gene;Acc:103033000]) HSP 1 Score: 128.257 bits (321), Expect = 6.775e-30 Identity = 94/295 (31.86%), Postives = 145/295 (49.15%), Query Frame = 2
Query: 1358 DDTKLLFDYGINQHSEVKFVCIRNLHDVEVIEEIDRGYYSILLKAKIKSKDKDIVLKKYTEIDLPDLNKNNVLLKELSIFQTLKSHHRFLKLFGIYKEENYFYIAMENMKGGSIKTHIK-KNKPL--DEKQIAFWSKQILEGLKYLHDQEFVYRDLKTSNILIDDKNDV-KLPSVSLSKYLHDYNRKPEQMGYQDNLPLRYMAPEILQQHP--YGIKADVWSFGAIIVEMVTGIQPYSELNETDAIQRIIQDRTIKYNTT-AISHNLKEFIGLCLIFNPEERSSDDKLMNHSFLN 2221
D L +DY ++H E V+ + +G + ++ + S + +K EI D + L +E+++ + LK H ++ G E + I ME + GGS+ ++ K PL +E I F++KQILEGLKYLHD + +RD+K N+LI+ + V K+ SK L N E L+YMAPEI+ + P YG AD+WS G I+EM TG P+ EL E A + I ++S K FI C +P+ R++ ++L+ H FL
Sbjct: 636 DSEALEYDYEYDEHGE------------RVV--LGKGTFGVVYAGRDLSNQVRLAIK---EIPERDSRYSQPLHEEIALHKHLK-HKNIVQYLGSISENGFIKIFMEQVPGGSLSALLRSKWGPLKNNEPTIGFYTKQILEGLKYLHDNQIAHRDIKGDNVLINTYSGVLKISDFGTSKRLAGINPCTETFTGT----LQYMAPEIIDKGPRGYGKPADIWSLGCTIIEMATGKPPFYELGEPQAAMFKVGMFKIHPEIPDSMSSEAKAFILRCFEPDPDLRATANELLTHEFLT 908
BLAST of Protein kinase domain-containing protein vs. Ensembl Cavefish
Match: map3k5 (mitogen-activated protein kinase kinase kinase 5 [Source:NCBI gene;Acc:103033000]) HSP 1 Score: 128.257 bits (321), Expect = 7.077e-30 Identity = 94/295 (31.86%), Postives = 145/295 (49.15%), Query Frame = 2
Query: 1358 DDTKLLFDYGINQHSEVKFVCIRNLHDVEVIEEIDRGYYSILLKAKIKSKDKDIVLKKYTEIDLPDLNKNNVLLKELSIFQTLKSHHRFLKLFGIYKEENYFYIAMENMKGGSIKTHIK-KNKPL--DEKQIAFWSKQILEGLKYLHDQEFVYRDLKTSNILIDDKNDV-KLPSVSLSKYLHDYNRKPEQMGYQDNLPLRYMAPEILQQHP--YGIKADVWSFGAIIVEMVTGIQPYSELNETDAIQRIIQDRTIKYNTT-AISHNLKEFIGLCLIFNPEERSSDDKLMNHSFLN 2221
D L +DY ++H E V+ + +G + ++ + S + +K EI D + L +E+++ + LK H ++ G E + I ME + GGS+ ++ K PL +E I F++KQILEGLKYLHD + +RD+K N+LI+ + V K+ SK L N E L+YMAPEI+ + P YG AD+WS G I+EM TG P+ EL E A + I ++S K FI C +P+ R++ ++L+ H FL
Sbjct: 644 DSEALEYDYEYDEHGE------------RVV--LGKGTFGVVYAGRDLSNQVRLAIK---EIPERDSRYSQPLHEEIALHKHLK-HKNIVQYLGSISENGFIKIFMEQVPGGSLSALLRSKWGPLKNNEPTIGFYTKQILEGLKYLHDNQIAHRDIKGDNVLINTYSGVLKISDFGTSKRLAGINPCTETFTGT----LQYMAPEIIDKGPRGYGKPADIWSLGCTIIEMATGKPPFYELGEPQAAMFKVGMFKIHPEIPDSMSSEAKAFILRCFEPDPDLRATANELLTHEFLT 916
BLAST of Protein kinase domain-containing protein vs. Ensembl Cavefish
Match: map3k5 (mitogen-activated protein kinase kinase kinase 5 [Source:NCBI gene;Acc:103033000]) HSP 1 Score: 127.487 bits (319), Expect = 1.139e-29 Identity = 87/262 (33.21%), Postives = 134/262 (51.15%), Query Frame = 2
Query: 1457 IDRGYYSILLKAKIKSKDKDIVLKKYTEIDLPDLNKNNVLLKELSIFQTLKSHHRFLKLFGIYKEENYFYIAMENMKGGSIKTHIK-KNKPL--DEKQIAFWSKQILEGLKYLHDQEFVYRDLKTSNILIDDKNDV-KLPSVSLSKYLHDYNRKPEQMGYQDNLPLRYMAPEILQQHP--YGIKADVWSFGAIIVEMVTGIQPYSELNETDAIQRIIQDRTIKYNTT-AISHNLKEFIGLCLIFNPEERSSDDKLMNHSFLN 2221
+ +G + ++ + S + +K EI D + L +E+++ + LK H ++ G E + I ME + GGS+ ++ K PL +E I F++KQILEGLKYLHD + +RD+K N+LI+ + V K+ SK L N E L+YMAPEI+ + P YG AD+WS G I+EM TG P+ EL E A + I ++S K FI C +P+ R++ ++L+ H FL
Sbjct: 652 LGKGTFGVVYAGRDLSNQVRLAIK---EIPERDSRYSQPLHEEIALHKHLK-HKNIVQYLGSISENGFIKIFMEQVPGGSLSALLRSKWGPLKNNEPTIGFYTKQILEGLKYLHDNQIAHRDIKGDNVLINTYSGVLKISDFGTSKRLAGINPCTETFTGT----LQYMAPEIIDKGPRGYGKPADIWSLGCTIIEMATGKPPFYELGEPQAAMFKVGMFKIHPEIPDSMSSEAKAFILRCFEPDPDLRATANELLTHEFLT 905
BLAST of Protein kinase domain-containing protein vs. Ensembl Cavefish
Match: map3k15 (mitogen-activated protein kinase kinase kinase 15 [Source:ZFIN;Acc:ZDB-GENE-091204-246]) HSP 1 Score: 127.102 bits (318), Expect = 1.648e-29 Identity = 85/259 (32.82%), Postives = 132/259 (50.97%), Query Frame = 2
Query: 1457 IDRGYYSILLKAKIKSKDKDIVLKKYTEIDLPDLNKNNVLLKELSIFQTLKSHHRFLKLFGIYKEENYFYIAMENMKGGSIKTHIK-KNKPLDEKQIAFWSKQILEGLKYLHDQEFVYRDLKTSNILIDDKNDV-KLPSVSLSKYLHDYNRKPEQMGYQDNLPLRYMAPEILQQHP--YGIKADVWSFGAIIVEMVTGIQPYSELNETDAIQRIIQDRTIKYNTT-AISHNLKEFIGLCLIFNPEERSSDDKLMNHSFL 2218
+ RG Y ++ + S I +K EI D + L +E+++ + LK + ++ G E+ Y I ME + GGS+ ++ K PL E I F+++QILEGL+YLH+ + V+RD+K N+L++ + V K+ SK L N E L+YMAPEI+ + P YG AD+WS G I+EM TG P+ EL E A + I ++S K FI C +P +R++ L+ F+
Sbjct: 647 LGRGTYGVVYAGRDLSNQVRIAIK---EIPERDSRYSQPLHEEIALHKYLKQRN-IVQYLGSVSEDGYIKIFMEQVPGGSLSALLRSKWGPLKEATIIFYTRQILEGLRYLHENQIVHRDIKGDNVLVNTYSGVLKISDFGTSKRLAGVNPCTETF----TGTLQYMAPEIIDKGPRGYGAPADIWSLGCTIIEMATGKPPFHELGEPQAAMFKVGMFKIHPEIPESLSTEAKSFILRCFEPDPNKRATAGDLLKDLFV 897
BLAST of Protein kinase domain-containing protein vs. Ensembl Sea Lamprey
Match: plk3 (polo-like kinase 3 (Drosophila) [Source:ZFIN;Acc:ZDB-GENE-030131-6134]) HSP 1 Score: 111.309 bits (277), Expect = 1.049e-25 Identity = 63/217 (29.03%), Postives = 116/217 (53.46%), Query Frame = 2
Query: 1580 KELSIFQTLKSHHR-FLKLFGIYKEENYFYIAMENMKGGSIKTHIKKNKPLDEKQIAFWSKQILEGLKYLHDQEFVYRDLKTSNILIDDKNDVKLPSVSLSKYLHDYNRKPEQMGYQDNLPLRYMAPEILQQHPYGIKADVWSFGAIIVEMVTGIQPYSELNETDAIQRIIQDRTIKYN-TTAISHNLKEFIGLCLIFNPEERSSDDKLMNHSFLNE 2224
+E+S+ + L HHR ++ +K+EN+ YI +E G S+ ++ K L E ++ ++ +Q++ GL+YLH V+RDLK N + D +VK+ + L+ L + + N Y+APE+L + +G +AD+WS G + M+ G P+S + + I R+ ++N ++SH ++ + L +P+ R+S L +H FL +
Sbjct: 74 QEISLHRKL--HHRHIVQFISSFKDENFIYIILELCNGQSLAHMLRSRKVLTETEVKYYLRQLISGLRYLHQCGVVHRDLKLGNFFVTDSMEVKIGDLGLATTLEPPEMRKRTVCGTPN----YLAPEVLNKRGHGPEADIWSLGCAVFTMLAGRPPFSTSDLANTYACI---RSGRFNFPPSLSHAARDLLTSALTPDPDLRASLLDLQSHPFLTQ 281
BLAST of Protein kinase domain-containing protein vs. Ensembl Sea Lamprey
Match: map3k2 (mitogen-activated protein kinase kinase kinase 2 [Source:ZFIN;Acc:ZDB-GENE-120215-96]) HSP 1 Score: 109.383 bits (272), Expect = 4.284e-25 Identity = 69/220 (31.36%), Postives = 110/220 (50.00%), Query Frame = 2
Query: 1568 NVLLKELSIFQTLKSHHRFLKLFGIYK--EENYFYIAMENMKGGSIKTHIKKNKPLDEKQIAFWSKQILEGLKYLHDQEFVYRDLKTSNILIDDKNDVKLPSVSLSKYLHDYNRKPEQMGYQDNLPLRYMAPEILQQHPYGIKADVWSFGAIIVEMVTGIQPYSELNETDAIQRIIQDRTIKYNTTAISHNLKEFIGLCLIFNPEERSSDDKLMNHSFLN 2221
N L E+ + + L+ H R ++ FG + ++ I ME M GGSIK ++ L E +++QILEG+ +LH V+RD+K +NIL D +VKL SK L + M P +M+PE++ YG KAD+WS G +VEM+T P++E AI +I T S + ++ + + + R S + L+ H F++
Sbjct: 404 NALECEIQLLKNLQ-HERIVQYFGCLRDPQQKTLSIFMEYMPGGSIKDQLRAYGALTENVTRKYTRQILEGVSFLHGNMIVHRDIKGANILRDSTGNVKLGDFGASKRLQTICSQGTAMRSVTGTPY-WMSPEVINGEGYGRKADIWSVGCTVVEMLTEKPPWAEFEAMAAIFKIATQPTDPRLPLHASEHARDLLRRIFV-EAKLRPSAEDLLRHPFVH 620
BLAST of Protein kinase domain-containing protein vs. Ensembl Sea Lamprey
Match: stk25a (serine/threonine kinase 25a [Source:ZFIN;Acc:ZDB-GENE-041010-92]) HSP 1 Score: 105.531 bits (262), Expect = 2.597e-24 Identity = 82/261 (31.42%), Postives = 134/261 (51.34%), Query Frame = 2
Query: 1451 EEIDRGYYSILLKAKIKSKDKDIVLKKYTEIDLPDLNKNNVLLK-ELSIFQTLKSHHRFLKLFGIYKEENYFYIAMENMKGGSIKTHIKKNKPLDEKQIAFWSKQILEGLKYLHDQEFVYRDLK--TSNILIDDKNDVKLPSVSLSKYLHDYNRKPEQMGYQDNLPLRYMAPEILQQHPYGIKADVWSFGAIIVEMVTGIQPYSELNETDAIQRIIQDR--TIKYNTTAISHNLKEFIGLCLIFNPEERSSDDKLMNHSFL 2218
E I +G + + K I ++ K++V K IDL + ++ E+++ S + FG Y + +I ME + GGS IK PL+E QIA ++IL+GL YLH + ++RD+K +N+L+ ++ DVKL ++ L D K P +MAPE+++Q Y KAD+WS G +E+ G P SEL+ + I ++ T++ N S KEF+ CL +P+ R + +L+ H F+
Sbjct: 30 ERIGKGSFGEVFKG-IDNRTKEVVAIKI--IDLEEAEDEIEDIQQEITVLSQCDSPY-VTHYFGSYLKGTKLWIIMEYLGGGSALDLIKPG-PLEEHQIATILREILKGLDYLHSERKIHRDIKGPAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTF---VGTPF-WMAPEVIKQSAYDFKADIWSLGITAIELAKGEPPNSELHPMRVLFLIPKNNPPTLEGN---YSKAFKEFVDSCLNKDPQFRPTAKELLKHKFI 278
BLAST of Protein kinase domain-containing protein vs. Ensembl Sea Lamprey
Match: phkg1b (phosphorylase kinase, gamma 1b (muscle) [Source:ZFIN;Acc:ZDB-GENE-050522-52]) HSP 1 Score: 103.605 bits (257), Expect = 6.695e-24 Identity = 77/304 (25.33%), Postives = 142/304 (46.71%), Query Frame = 2
Query: 1379 DYGINQHSEVKFVCIRNLHD-VEVIEEIDRGYYSILLKAKIKSKDKDIVLK-------KYTEIDLPDLNKNNVLLKELSIFQTLKSHHRFLKLFGIYKEENYFYIAMENMKGGSIKTHIKKNKPLDEKQIAFWSKQILEGLKYLHDQEFVYRDLKTSNILIDDKNDVKLPSVSLSKYLHDYNRKPEQMGYQDNLPLRYMAPEIL-----QQHP-YGIKADVWSFGAIIVEMVTGIQPYSELNETDAIQRIIQDRTIKYNTTAI---SHNLKEFIGLCLIFNPEERSSDDKLMNHSFLNE*NVKE 2239
D I + + V ++ +D E E + G S++ + K +D +K + +E +L D+ + V KE+ I + + H + L Y+ +F++ + MK G + ++ + L EK + I E + +LH + V+RDLK NIL+DD +++L S L R E G Y++PE+L + HP YG + D+W+ G I+ ++ G P+ + + R+I D ++T S +K+ I L+ PE+R + ++ + H F + +V+E
Sbjct: 4 DLAIPEGDHTEPVAAQDFNDKYEPKEVLGSGVSSVVRRCVHKRTGQDFAVKIIDITPDRLSEEELEDIYSSTV--KEVDILKAVSGHPHIITLIDAYESSTFFFLVFDLMKRGELFDYLTEKVALSEKDTRSIMRSIFEVVHFLHAKNIVHRDLKPENILLDDNMNIRLSDFGFSMQLRPGERLRELCGTPG-----YLSPELLKCSMDESHPGYGKEVDLWACGVIMYTLLAGSPPFWHRKQMTML-RLIMDGKYDFSTPEWEDRSDTVKDLISRLLVVEPEKRFTAEQALAHPFFQQYDVEE 299
BLAST of Protein kinase domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000009481.1 (pep scaffold:Pmarinus_7.0:GL477866:614:5163:1 gene:ENSPMAG00000008570.1 transcript:ENSPMAT00000009481.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 103.219 bits (256), Expect = 1.867e-23 Identity = 70/267 (26.22%), Postives = 134/267 (50.19%), Query Frame = 2
Query: 1439 VEVIEEIDRGYYSI----LLKAKIKSKDKDIVLKKYTEIDLPDLNKNNVLLKELSIFQTLKSHHRFLKLFGIYKEENYFYIAMENMKGGSIKTHIKKNKPLDEK----------QIAFWSKQILEGLKYLHDQEFVYRDLKTSNILIDDKNDVKLPSVSLSK--YLHDYNRKPEQMGYQDNLPLRYMAPEILQQHPYGIKADVWSFGAIIVEMVTGI-QPYSELNETDAIQRIIQDRTIKYNTTAISHNLKEFIGLCLIFNPEERSS 2188
V+++ E+ +G + + L + +K +D+ V K T + + + L E S+ ++ HH ++L G+ + + ME M G +K++++ +P EK ++ + +I +G+ YL+ ++FV+RDL N ++ + VK+ +++ Y DY RK G + LP+R+M+PE L+ + +DVWSFG ++ E+ T QPY L+ + + + + D + A L+E I C +NP R +
Sbjct: 61 VKMMRELGQGTFGMVYEGLARGIVKGEDETRVAIK-TVNETATMRERYEFLNEASVMKSFNCHH-VVRLLGVVSQAQPILVIMELMTRGDLKSYLRSLRPDAEKKPTRPPSSLPEMLQMAGEIADGMAYLNAKKFVHRDLAARNCMVAEDFTVKIGDFGMTRDIYETDYYRK----GGKGLLPVRWMSPESLKDGVFTTHSDVWSFGVVLWEIATQAEQPYQGLS-NEQVLKFVMDGGLLVLPPACPERLQELIRKCWQYNPRMRPT 320
BLAST of Protein kinase domain-containing protein vs. Ensembl Yeast
Match: CDC15 (Protein kinase of the Mitotic Exit Network; localized to the spindle pole bodies at late anaphase; promotes mitotic exit by directly switching on the kinase activity of Dbf2p; required for spindle disassembly after meiosis II; relocalizes to the cytoplasm upon DNA replication stress [Source:SGD;Acc:S000000072]) HSP 1 Score: 115.546 bits (288), Expect = 6.535e-27 Identity = 77/257 (29.96%), Postives = 130/257 (50.58%), Query Frame = 2
Query: 1457 IDRGYYSILLKAKIKSKDKDIVLKKYTEIDLPDLNKNNVLLKELSIFQTLKSHHRFLKLFGIYKEENYFYIAMENMKGGSIKTHIKKNKP-LDEKQIAFWSKQILEGLKYLHDQEFVYRDLKTSNILIDDKNDVKLPSVSLSKYLHDYNRKPEQMGYQDNLPLRYMAPEILQQHPYGIKADVWSFGAIIVEMVTGIQPYSELNETDAIQRIIQDRTIKYNTTAISHNLKEFIGLCLIFNPEERSSDDKLMNHSFLNE 2224
I RG Y ++ KA K D+ + +K+ + +LN ++ E+S+ + L +H+ +K G ++ YI +E GS++ I ++ L E + + Q L GLKYLH + ++RD+K +NIL+ N VKL +S + N + L +MAPEIL +D+WS GA +VEM+T PY L + + + D Y ++ S LK+F+ C + N +R + D+L+ H ++N
Sbjct: 31 IGRGSYGVVYKAINKHTDQVVAIKEVVYENDEELND---IMAEISLLKNL-NHNNIVKYHGFIRKSYELYILLEYCANGSLRRLISRSSTGLSENESKTYVTQTLLGLKYLHGEGVIHRDIKAANILLSADNTVKLADFGVSTIV---NSSALTLAGT----LNWMAPEILGNRGASTLSDIWSLGATVVEMLTKNPPYHNLTDANIYYAVEND--TYYPPSSFSEPLKDFLSKCFVKNMYKRPTADQLLKHVWINS 274
BLAST of Protein kinase domain-containing protein vs. Ensembl Yeast
Match: KIC1 (Protein kinase of the PAK/Ste20 family, required for cell integrity; physically interacts with Cdc31p (centrin), which is a component of the spindle pole body; part of the RAM network that regulates cellular polarity and morphogenesis [Source:SGD;Acc:S000001144]) HSP 1 Score: 114.39 bits (285), Expect = 1.834e-26 Identity = 65/214 (30.37%), Postives = 117/214 (54.67%), Query Frame = 2
Query: 1580 KELSIFQTLKSHHRFLKLFGIYKEENYFYIAMENMKGGSIKTHIKKNKPLDEKQIAFWSKQILEGLKYLHDQEFVYRDLKTSNILIDDKNDVKLPSVSLSKYLHDYNRKPEQMGYQDNLPLRYMAPEILQQHPY-GIKADVWSFGAIIVEMVTGIQPYSELNETDAIQRIIQDRTIKYNTTAISHNLKEFIGLCLIFNPEERSSDDKLMNHSFL 2218
+E+ +LK + +G Y ++ +I ME+ GGS+++ ++ K +DEK I +++L LK +H ++RD+K +N+LI ++ +VKL ++ ++ + + + M +MAPE++ + Y K D+WS G E+ TG PY ++ A+Q II+ + + + S +LKEFI LCL +P+ER S D L+ F+
Sbjct: 68 REIQFLASLKQISNITRYYGSYLKDTSLWIIMEHCAGGSLRSLLRPGK-IDEKYIGVIMRELLVALKCIHKDNVIHRDIKAANVLITNEGNVKLCDFGVAAQVNQTSLRRQTMAGTP----YWMAPEVIMEGVYYDTKVDIWSLGITTYEIATGNPPYCDVEALRAMQLIIKSKPPRLEDRSYSTSLKEFIALCLDEDPKERLSADDLLKSKFI 276
BLAST of Protein kinase domain-containing protein vs. Ensembl Yeast
Match: STE11 (Signal transducing MEK kinase; involved in pheromone response and pseudohyphal/invasive growth pathways where it phosphorylates Ste7p, and the high osmolarity response pathway, via phosphorylation of Pbs2p; regulated by Ste20p and Ste50p; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000004354]) HSP 1 Score: 111.694 bits (278), Expect = 6.792e-26 Identity = 68/230 (29.57%), Postives = 121/230 (52.61%), Query Frame = 2
Query: 1550 PDLNKN------NVLLKELSIFQTLKSHHRFLKLFGIYKEENYFYIAMENMKGGSIKTHIKKNKPLDEKQIAFWSKQILEGLKYLHDQEFVYRDLKTSNILIDDKNDVKLPSVSLSKYLHDYNRKPEQMGYQDNLPLRYMAPEILQQHPYGIKADVWSFGAIIVEMVTGIQPYSELNETDAIQRIIQDRTIKYNTTAISHNLKEFIGLCLIFNPEERSSDDKLMNHSFLN 2221
P N+N + L E+++ + L H + +G +E I +E + GGS+ + + P +E I +++QIL G+ YLH + ++RD+K +NILID K VK+ +SK L N+K + + +M+PE+++Q KAD+WS G +++EM TG P+ + ++ AI +I + T + + A S K F+ + + R S +L+ H +L+
Sbjct: 487 PKTNQNIHRKMVDALQHEMNLLKELH-HENIVTYYGASQEGGNLNIFLEYVPGGSVSSMLNNYGPFEESLITNFTRQILIGVAYLHKKNIIHRDIKGANILIDIKGCVKITDFGISKKLSPLNKKQNKRASLQG-SVFWMSPEVVKQTATTAKADIWSTGCVVIEMFTGKHPFPDFSQMQAIFKIGTNTTPEIPSWATSEG-KNFLRKAFELDYQYRPSALELLQHPWLD 713
BLAST of Protein kinase domain-containing protein vs. Ensembl Yeast
Match: CLA4 (Cdc42p-activated signal transducing kinase; member of the PAK (p21-activated kinase) family, along with Ste20p and Skm1p; involved in septin ring assembly, vacuole inheritance, cytokinesis, sterol uptake regulation; phosphorylates Cdc3p and Cdc10p; CLA4 has a paralog, SKM1, that arose from the whole genome duplication [Source:SGD;Acc:S000005242]) HSP 1 Score: 109.383 bits (272), Expect = 5.463e-25 Identity = 64/195 (32.82%), Postives = 106/195 (54.36%), Query Frame = 2
Query: 1661 FYIAMENMKGGSI-------KTHIKKNKPLDEKQIAFWSKQILEGLKYLHDQEFVYRDLKTSNILIDDKNDVKLPSVSLSKYLHDYNRKPEQMGYQDNLPLRYMAPEILQQHPYGIKADVWSFGAIIVEMVTGIQPYSELNETDAIQRIIQDRTIKY-NTTAISHNLKEFIGLCLIFNPEERSSDDKLMNHSFLN 2221
++ ME M+GGS+ T+ + PL E QIA+ ++ +GLK+LHD+ ++RD+K+ N+L+D + VK+ L D K M P +MAPE+++Q Y K DVWS G + +EM+ G PY + A+ I + T K + ++S +K F+ +CL + R+S ++L++H F N
Sbjct: 636 LWVVMEFMEGGSLTDIIENSPTNDNSHSPLTEPQIAYIVRETCQGLKFLHDKHIIHRDIKSDNVLLDTRARVKITDFGFCARLTDKRSKRATMV---GTPY-WMAPEVVKQREYDEKIDVWSLGIMTIEMLEGEPPYLNEDPLKALYLIATNGTPKLKHPESLSLEIKRFLSVCLCVDVRYRASTEELLHHGFFN 826
BLAST of Protein kinase domain-containing protein vs. Ensembl Yeast
Match: STE20 (Cdc42p-activated signal transducing kinase; involved in pheromone response, pseudohyphal/invasive growth, vacuole inheritance, down-regulation of sterol uptake; GBB motif binds Ste4p; member of the PAK (p21-activated kinase) family [Source:SGD;Acc:S000000999]) HSP 1 Score: 107.071 bits (266), Expect = 2.800e-24 Identity = 71/225 (31.56%), Postives = 121/225 (53.78%), Query Frame = 2
Query: 1562 KNNVLLKELSIFQTLKSHHRFLKLFGIYKEENYFYIAMENMKGGSIKTHIKKNKPLDEKQIAFWSKQILEGLKYLHDQEFVYRDLKTSNILIDDKNDVKLPSVSLSKYLHDYNRKPEQM-GYQDNLPLRYMAPEILQQHPYGIKADVWSFGAIIVEMVTGIQPYSELNETD--AIQRIIQDRTIKYNTTA-ISHNLKEFIGLCLIFNPEERSSDDKLMNHSFLNE 2224
K +++ E+ + + K H + Y + ++ ME M+GGS+ T + + L E QI ++ L GL++LH + ++RD+K+ NIL+ + D+KL +++ N K M G +MAPE++ + YG K D+WS G +I+EM+ G PY LNET A+ I + T K +S +LK+F+ CL PE+R+S +L++ ++ E
Sbjct: 658 KKELIINEILVMKGSK-HPNIVNFIDSYVLKGDLWVIMEYMEGGSL-TDVVTHCILTEGQIGAVCRETLSGLEFLHSKGVLHRDIKSDNILLSMEGDIKLTDFGFCAQINELNLKRTTMVGTP-----YWMAPEVVSRKEYGPKVDIWSLGIMIIEMIEGEPPY--LNETPLRALYLIATNGTPKLKEPENLSSSLKKFLDWCLCVEPEDRASATELLHDEYITE 873
BLAST of Protein kinase domain-containing protein vs. Ensembl Nematostella
Match: EDO41410 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S4G7]) HSP 1 Score: 125.946 bits (315), Expect = 2.828e-32 Identity = 85/254 (33.46%), Postives = 130/254 (51.18%), Query Frame = 2
Query: 1508 DKDIVLKKYTEIDLPDLNKNNVLLKELSI-FQTLKSHHRFLKLFGIYKEENYFYIAMENMKGGSIKTHIKKNKPLDEKQIAFWSKQILEGLKYLHDQEFVYRDLKTSNILIDDKNDVKLPSVSLSKYLHDYNRKPEQMGYQD--NLPLRYMAPEILQQHPYGIKADVWSFGAIIVEMVTGIQPYSELNETDAIQRIIQDRTIKYNTTAISHNLKEFIGLCLIFNPEERSSDDKLMNHSFLNE*NVKEFNICSCL 2260
+++ +K+ L KN V E I F + R ++ +GI ++ + YI ME + GGSI HIK++ L+E +S+QILEG+ YLH V+RD+K +NIL D +VKL SK L K G++ P +MAPE++ YG KADVWS G +VEM+T P+++ A+ +I T + +S + EF+ L N + R S D+L+ SF V ++ +CL
Sbjct: 27 GRELAVKQIETGQLNSSTKNEVKALEGEIEFMKAFRNERIVQYYGIETDDLHIYIFMEYLPGGSIHEHIKQHGALNESLTRKYSRQILEGILYLHTNRIVHRDIKGANILRDLYGNVKLADFGASKRLQTIRSK---TGFRSVHGTPY-WMAPEVINGEGYGRKADVWSVGCTVVEMLTTKPPWADFEPMAALFKIATQPTEPELPSDLSVDAVEFVRSTLRMNSKSRPSADELLRFSF-----VTNSSMSTCL 271
BLAST of Protein kinase domain-containing protein vs. Ensembl Nematostella
Match: EDO42845 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S0A9]) HSP 1 Score: 124.79 bits (312), Expect = 2.563e-31 Identity = 85/276 (30.80%), Postives = 145/276 (52.54%), Query Frame = 2
Query: 1442 EVIEEIDRGYYSILLKAKIKSKDKDIVLKKYTEIDLPDLNKNNVLLKELSIFQTLKSHHRFLKLFGIYKEENYFYIAMENMKGGSIKTHIK-KNKPLDEKQIAFWSKQILEGLKYLHDQEFVYRDLKTSNILIDDKNDVKLPSVSLSKYLHDYNRKPEQMGYQDNLPLRYMAPEILQQHPYGIKADVWSFGAIIVEMVTGIQPYSELNETDAIQRIIQDRTIKYNTTA-ISHNLKEFIGLCLIFNPEERSSDDKLMNHSFLNE*NVKEFNICSCLF 2263
+V+E++ G Y + KA K + + +K+ +D DL + ++KE+S+ Q S + +K +G Y + +I ME GS+ +K +NK L E++I K L+GL+YLH + ++RD+K NIL++ + KL ++ L D K + P +MAPE++Q+ Y AD+WS G +EM G PY++++ AI I + S + K+F+ CL+ NPEER++ +L+ HSF+ K+ +I S +
Sbjct: 25 DVLEKLGEGSYGSVFKAMHKESGQVVAIKQ-VPVDT-DLQE---IIKEISMMQQCDSPY-VVKYYGSYFKNTDLWIVMEYCGAGSVSDLMKIRNKTLTEEEIKCVLKYTLKGLEYLHLRRKIHRDIKAGNILLNSEGHAKLADFGVAGQLTDTMAKRNTV---IGTPF-WMAPEVIQEVGYDCLADIWSLGITAMEMAEGKPPYADIHPMRAIFMIPTKPPPTFRDPGQWSEDFKDFVSKCLVKNPEERATATELLQHSFIQ--GAKQISILSSMI 288
BLAST of Protein kinase domain-containing protein vs. Ensembl Nematostella
Match: EDO45846 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RRL1]) HSP 1 Score: 115.546 bits (288), Expect = 2.229e-28 Identity = 75/277 (27.08%), Postives = 139/277 (50.18%), Query Frame = 2
Query: 1394 QHSEVKFVCIRNLHDVEVIEEIDRGYYSILLKAKIKSKDKDIVLKKYTEIDLPDLNKNNVLLKELSIFQTLKSHHRFLKLFGIYKEENYFYIAMENMKGGSIKTHIKKNKPLDEKQIAFWSKQILEGLKYLHDQEFVYRDLKTSNILIDDKNDVKLPSVSL-SKYLHDYNRKPEQMGYQDNLPLRYMAPEILQQHPYGIKADVWSFGAIIVEMVTGIQPYSELNETDAIQRIIQ-DRTIKYNTTAISHNLKEFIGLCLIFNPEERSSDDKLMNHSFL 2218
+H EV R ++ +I G I+ A K + + +KK +DL + +L E+ I + H ++++G + + ++ ME ++GG++ T I + L E+Q+A + +L+ L +LH Q ++RD+K+ +IL+ VKL ++ D R+ +G +MAPE++ + PYG + D+WS G +++EMV G PY A++++ + N IS L+ F+ LI +P R++ +L+NH F+
Sbjct: 14 RHLEVVVQSTRQPENLGNFMKIGEGSTGIVCLATDKRTGRQVAVKK---MDLKKQQRRELLFNEVVIMRDYP-HPNIVEMYGSHLVGDELWVVMEFLEGGTL-TDIVTHTNLSEEQVACVCRAVLKALTFLHSQGVIHRDIKSDSILLTSNGTVKLSDFGFCAQVTEDMPRRKSLVGTP-----YWMAPEVISRKPYGTEVDIWSLGIMVLEMVDGEPPYFNEPPLQAMRKLRDLEPPTSRNPIQISPRLQSFLDNALIRDPLYRATAFELLNHPFI 280
BLAST of Protein kinase domain-containing protein vs. Ensembl Nematostella
Match: EDO49138 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RH03]) HSP 1 Score: 108.227 bits (269), Expect = 2.925e-26 Identity = 72/260 (27.69%), Postives = 129/260 (49.62%), Query Frame = 2
Query: 1448 IEEIDRGYYSILLKAKIKSKDKDIVLKKYTEIDLPDLNKNNVLLKELSIFQTLKSHHRFLKLFGIYKEENYFYIAMENMKGGSIKTHIKKN-KPLDEKQIAFWSKQILEGLKYLHDQEFVYRDLKTSNILIDDKNDVKLPSVSLSKYLH---DYNRKPEQMGYQDNLPLRYMAPEILQQHPYGIKADVWSFGAIIVEMVTGIQPYSELNETDAIQRIIQDRTIKYNTTAISHN----LKEFIGLCLIFNPEERSSDDKLM 2203
I+ I +G + + + + LK+ +P +++ + L E+ I TLK H ++ ++E FYI ME +GG + T IK+ +P ++I W Q+L LK++H Q ++RDLKT NI + + VK+ +++ L D+ R Y Y++PEI Q+ PY K+D+W+ G ++ E+ T P++ N T+ + +I+ N I L++ + + L NP +R S +L+
Sbjct: 7 IDIIGKGTFGSAWLVESRQSKRLYALKELNATAMPSEDRH-LALNEVKILSTLK-HRNIVRYRDAFEETGRFYIVMEYAEGGDLHTKIKQAVEPFSSERILNWLAQLLLALKHIHGQNILHRDLKTQNIFLTKDDVVKIGDFGIARILDSTCDHARTTVGTPY-------YLSPEICQRQPYNNKSDIWALGCVLYELTTRTHPFTADNLTNLVVKILHG-----NYPPIPRFYGPLLEDLVAVMLKINPADRPSAKQLI 252
BLAST of Protein kinase domain-containing protein vs. Ensembl Nematostella
Match: EDO27976 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T7S3]) HSP 1 Score: 107.842 bits (268), Expect = 5.844e-26 Identity = 53/161 (32.92%), Postives = 87/161 (54.04%), Query Frame = 2
Query: 1571 VLLKELSIFQTLKSHHRFLKLFGIYKEENYFYIAMENMKGGSIKTHIKKNKPLDEKQIAFWSKQILEGLKYLHDQEFVYRDLKTSNILIDDKN-DVKLPSVSLSKYLHDYNRKPEQMGYQDNLPLRYMAPEILQQHPYGIKADVWSFGAIIVEMVTGIQPY 2050
++ E++I LK H +K G + +F I +E M GGSI + K P +E + + +QIL+G+ YLH+ + V+RD+K +NIL+D D+++ + L + Q + +MAPE+L+ YG DVWS G +++EM TG P+
Sbjct: 86 TIMDEIAILARLK-HPHLIKCLGATRHTGHFNIFLEWMAGGSISMLLSKYGPFEEAILIRYLRQILQGVSYLHENQVVHRDIKGANILVDSTGQDIRIADFGAAARLATQITGAGEFQGQLLGTIAFMAPEVLRGESYGRSCDVWSVGCVLIEMATGKPPW 245
BLAST of Protein kinase domain-containing protein vs. Ensembl Medaka
Match: ENSORLT00000044704.1 (serine/threonine-protein kinase 4 [Source:NCBI gene;Acc:101175466]) HSP 1 Score: 129.798 bits (325), Expect = 1.454e-31 Identity = 82/262 (31.30%), Postives = 138/262 (52.67%), Query Frame = 2
Query: 1442 EVIEEIDRGYYSILLKAKIKSKDKDIVLKKY-TEIDLPDLNKNNVLLKELSIFQTLKSHHRFLKLFGIYKEENYFYIAMENMKGGSIKTHIK-KNKPLDEKQIAFWSKQILEGLKYLHDQEFVYRDLKTSNILIDDKNDVKLPSVSLSKYLHDYNRKPEQMGYQDNLPLRYMAPEILQQHPYGIKADVWSFGAIIVEMVTGIQPYSELNETDAIQRIIQDRTIKY-NTTAISHNLKEFIGLCLIFNPEERSSDDKLMNHSFL 2218
+V+E++ G Y + KA K + + +K+ E DL ++ +KE+SI Q S H ++ +G Y + + +I ME GS+ I+ +NK L E++IA L+GL+YLH ++RD+K NIL++ + KL ++ L D K + P +MAPE++Q+ Y AD+WS G +EM G PY++++ AI I + + N S N ++F+ CL+ NPE R++ +L+ H F+
Sbjct: 34 DVLEKLGEGSYGCVFKANYKETGEIVAIKQVPVESDLQEI------IKEISIMQQCNSPH-VVRYYGSYFKNSDLWIVMEYCGAGSVSDIIRIRNKTLSEEEIATVVHSTLKGLEYLHFMRKIHRDIKAGNILLNAEGQAKLADFGVAGQLTDTMAKRNTV---IGTPF-WMAPEVIQEIGYNCVADIWSLGITAIEMAEGKPPYADIHPMRAIFMIPTNPPPTFRNPDLWSENFRDFVSQCLVKNPENRATATQLLQHPFI 284
BLAST of Protein kinase domain-containing protein vs. Ensembl Medaka
Match: ENSORLT00000024938.2 (serine/threonine-protein kinase 4 [Source:NCBI gene;Acc:101175466]) HSP 1 Score: 129.028 bits (323), Expect = 3.496e-31 Identity = 82/262 (31.30%), Postives = 138/262 (52.67%), Query Frame = 2
Query: 1442 EVIEEIDRGYYSILLKAKIKSKDKDIVLKKY-TEIDLPDLNKNNVLLKELSIFQTLKSHHRFLKLFGIYKEENYFYIAMENMKGGSIKTHIK-KNKPLDEKQIAFWSKQILEGLKYLHDQEFVYRDLKTSNILIDDKNDVKLPSVSLSKYLHDYNRKPEQMGYQDNLPLRYMAPEILQQHPYGIKADVWSFGAIIVEMVTGIQPYSELNETDAIQRIIQDRTIKY-NTTAISHNLKEFIGLCLIFNPEERSSDDKLMNHSFL 2218
+V+E++ G Y + KA K + + +K+ E DL ++ +KE+SI Q S H ++ +G Y + + +I ME GS+ I+ +NK L E++IA L+GL+YLH ++RD+K NIL++ + KL ++ L D K + P +MAPE++Q+ Y AD+WS G +EM G PY++++ AI I + + N S N ++F+ CL+ NPE R++ +L+ H F+
Sbjct: 34 DVLEKLGEGSYGCVFKANYKETGEIVAIKQVPVESDLQEI------IKEISIMQQCNSPH-VVRYYGSYFKNSDLWIVMEYCGAGSVSDIIRIRNKTLSEEEIATVVHSTLKGLEYLHFMRKIHRDIKAGNILLNAEGQAKLADFGVAGQLTDTMAKRNTV---IGTPF-WMAPEVIQEIGYNCVADIWSLGITAIEMAEGKPPYADIHPMRAIFMIPTNPPPTFRNPDLWSENFRDFVSQCLVKNPENRATATQLLQHPFI 284
BLAST of Protein kinase domain-containing protein vs. Ensembl Medaka
Match: si:ch211-1i11.3 (mitogen-activated protein kinase kinase kinase 5 [Source:NCBI gene;Acc:101167985]) HSP 1 Score: 129.413 bits (324), Expect = 3.123e-30 Identity = 88/261 (33.72%), Postives = 134/261 (51.34%), Query Frame = 2
Query: 1457 IDRGYYSILLKAKIKSKDKDIVLKKYTEIDLPDLNKNNVLLKELSIFQTLKSHHRFLKLFGIYKEENYFYIAMENMKGGSIKTHIK-KNKPL--DEKQIAFWSKQILEGLKYLHDQEFVYRDLKTSNILIDDKNDV-KLPSVSLSKYLHDYNRKPEQMGYQDNLPLRYMAPEILQQHP--YGIKADVWSFGAIIVEMVTGIQPYSELNETDAIQRIIQDRTIKYNTT-AISHNLKEFIGLCLIFNPEERSSDDKLMNHSFL 2218
+ +G Y ++ + S I +K EI D + L +E+++ + LK H ++ G ++ + I ME + GGS+ + ++ K PL +E I F++KQ+LEGLKYLHD + V+RD+K N+LI+ + V K+ SK L N E L+YMAPEI+ Q P YG AD+WS G I+EM TG P+ EL A + I +S K FI C NP+ R++ +L+ +FL
Sbjct: 583 LGKGTYGVVYAGRDLSNQVRIAIK---EIPEKDSTYSQPLHEEIALHKRLK-HRNIVQYLGSVSQDGFIKIFMEEVPGGSLSSLLRSKWGPLKDNEPTIIFYTKQVLEGLKYLHDNQIVHRDIKGDNVLINTYSGVLKISDFGTSKRLAGINPCTETFAGT----LQYMAPEIIDQGPRGYGKPADIWSLGCTIIEMATGKTPFHELGSPQAAMFKVGMFKIHPKVPECMSDEAKGFIMSCFEPNPDNRATAAELLMDTFL 835
BLAST of Protein kinase domain-containing protein vs. Ensembl Medaka
Match: si:ch211-1i11.3 (mitogen-activated protein kinase kinase kinase 5 [Source:NCBI gene;Acc:101167985]) HSP 1 Score: 129.413 bits (324), Expect = 3.385e-30 Identity = 88/261 (33.72%), Postives = 134/261 (51.34%), Query Frame = 2
Query: 1457 IDRGYYSILLKAKIKSKDKDIVLKKYTEIDLPDLNKNNVLLKELSIFQTLKSHHRFLKLFGIYKEENYFYIAMENMKGGSIKTHIK-KNKPL--DEKQIAFWSKQILEGLKYLHDQEFVYRDLKTSNILIDDKNDV-KLPSVSLSKYLHDYNRKPEQMGYQDNLPLRYMAPEILQQHP--YGIKADVWSFGAIIVEMVTGIQPYSELNETDAIQRIIQDRTIKYNTT-AISHNLKEFIGLCLIFNPEERSSDDKLMNHSFL 2218
+ +G Y ++ + S I +K EI D + L +E+++ + LK H ++ G ++ + I ME + GGS+ + ++ K PL +E I F++KQ+LEGLKYLHD + V+RD+K N+LI+ + V K+ SK L N E L+YMAPEI+ Q P YG AD+WS G I+EM TG P+ EL A + I +S K FI C NP+ R++ +L+ +FL
Sbjct: 639 LGKGTYGVVYAGRDLSNQVRIAIK---EIPEKDSTYSQPLHEEIALHKRLK-HRNIVQYLGSVSQDGFIKIFMEEVPGGSLSSLLRSKWGPLKDNEPTIIFYTKQVLEGLKYLHDNQIVHRDIKGDNVLINTYSGVLKISDFGTSKRLAGINPCTETFAGT----LQYMAPEIIDQGPRGYGKPADIWSLGCTIIEMATGKTPFHELGSPQAAMFKVGMFKIHPKVPECMSDEAKGFIMSCFEPNPDNRATAAELLMDTFL 891
BLAST of Protein kinase domain-containing protein vs. Ensembl Medaka
Match: map3k15 (mitogen-activated protein kinase kinase kinase 15 [Source:NCBI gene;Acc:101156777]) HSP 1 Score: 124.79 bits (312), Expect = 9.555e-29 Identity = 85/259 (32.82%), Postives = 129/259 (49.81%), Query Frame = 2
Query: 1457 IDRGYYSILLKAKIKSKDKDIVLKKYTEIDLPDLNKNNVLLKELSIFQTLKSHHRFLKLFGIYKEENYFYIAMENMKGGSIKTHIK-KNKPLDEKQIAFWSKQILEGLKYLHDQEFVYRDLKTSNILIDDKNDV-KLPSVSLSKYLHDYNRKPEQMGYQDNLPLRYMAPEILQQHP--YGIKADVWSFGAIIVEMVTGIQPYSELNETDAIQRIIQDRTIKYNTT-AISHNLKEFIGLCLIFNPEERSSDDKLMNHSFL 2218
+ RG Y ++ + S I +K EI D + L +E+++ + LK H ++ G E + I ME + GGS+ ++ K PL E I F+++QILEGL+YLH+ + V+RD+K N+L++ + V K+ SK L N E L+YMAPEI+ + P YG AD+WS G I+EM TG P+ EL E A + I ++S K FI C +P +R L+ F+
Sbjct: 624 LGRGTYGVVYAGRDLSNQVRIAIK---EIPERDSRYSQPLHEEIALHKYLK-HRNIVQYLGSISENGFIKIFMEQVPGGSLSALLRSKWGPLKEATIIFYTRQILEGLRYLHENQIVHRDIKGDNVLVNTYSGVLKISDFGTSKRLAGVNPCTETF----TGTLQYMAPEIIDKGPRGYGAPADIWSLGCTIIEMATGKPPFHELGEPQAAMFKVGMFKIHPEIPESLSLEAKSFILRCFEPDPNKRPITTDLLKDPFI 874
BLAST of Protein kinase domain-containing protein vs. Planmine SMEST
Match: SMESG000074938.1 (SMESG000074938.1) HSP 1 Score: 1413.67 bits (3658), Expect = 0.000e+0 Identity = 720/742 (97.04%), Postives = 721/742 (97.17%), Query Frame = 2
Query: 56 MGVISWIRLDILLFLIFVTHQEQPLSICHIDRPFKTMDNTCMNFNELCVKKEDPECNNFKSVCTQCPPVNYTFIMFQKLNRLIEDQKRVEIKTKEINEAVEKLSLKKEIKSVLNSILAFVIILPVLLFIGLLYLIRKNKLSIKVRSRKVKISENEEQGDMLKPLIISQQVSENEEQGDMLKPLIISQQ-------------------DLKIDERXXXXXXXXXXXXXXNFQKLQAFQGIFANQNKDTKFQLKAAAHPIELNIHIDENIVQIKRKIVSKCPTLRKGCYKIMKLHYNGKVLDDNQYFFSCVSCRDVIISCEVNQSLDPNEIIVLNVHSKERMPDLLQIKKTQAVSELKEIISKIIQRKNFVIFQESKELIDSELINESKLVDFDWIKVIIKNHEEIFLRSIFDERENLVVEFESSDMVSTLKSNLANNVNSSPDNYALFYYNEYLDDTKLLFDYGINQHSEVKFVCIRNLHDVEVIEEIDRGYYSILLKAKIKSKDKDIVLKKYTEIDLPDLNKNNVLLKELSIFQTLKSHHRFLKLFGIYKEENYFYIAMENMKGGSIKTHIKKNKPLDEKQIAFWSKQILEGLKYLHDQEFVYRDLKTSNILIDDKNDVKLPSVSLSKYLHDYNRKPEQMGYQDNLPLRYMAPEILQQHPYGIKADVWSFGAIIVEMVTGIQPYSELNETDAIQRIIQDRTIKYNTTAISHNLKEFIGLCLIFNPEERSSDDKLMNHSFLNE 2224
M VISWIRLDILLFLI VTHQEQPLSICHIDRPFKTMDNTCMNFNELCVKKEDPECNNFKSVCTQCPPVNYTFIMFQKLNRLIEDQKRVEIKTKEINEAVEKLSLKKEIKSVLNSILAFVIILPVLLFIGLLYLIRKNKLSIKVRSRKVKISENEEQGDMLKPLIISQQVSENEEQGDMLKPLIISQQ DLKIDERFKEFKLFLDLKLEENFQKLQAFQGIFANQNKDTKFQLKAAAHPIELNIHIDENIVQIKRKIVSKCPTLRKGCYKIMKLHYNGKVLDDNQYFFSCVSCRDVIISCEVNQSLDPNEIIVLNVHSKERMPDLLQIKKTQAVSELKEIISKIIQRKNFVIFQESKELIDSELINESKLVDFDWIKVIIKNHEEIFLRSIFDERENLVVEFESSDMVSTLKSNLANNVNSSPDNYALFYYNEYLDDTKLLFDYGINQHSEVKFVCIRNLHDVEVIEEIDRGYYS+LLKAKIKSKDKDIVLKKYTEIDLPDLNKNNVLLKELSIFQTLKSHHRFLKLFGIYKEENYFYIAMENMKGGSIKTHIKKNKPLDEKQIAFWSKQILEGLKYLHDQEFVYRDLKTSNILIDDKNDVKLPSVSLSKYLHDYNRKPEQMGYQDNLPLRYMAPEILQQHPYGIKADVWSFGAIIVEMVTGIQPYSELNETDAIQRIIQDRTIKYNTTAISHNLKEFIGLCLIFNPEERSSDDKLMNHSFLNE
Sbjct: 1 MDVISWIRLDILLFLISVTHQEQPLSICHIDRPFKTMDNTCMNFNELCVKKEDPECNNFKSVCTQCPPVNYTFIMFQKLNRLIEDQKRVEIKTKEINEAVEKLSLKKEIKSVLNSILAFVIILPVLLFIGLLYLIRKNKLSIKVRSRKVKISENEEQGDMLKPLIISQQVSENEEQGDMLKPLIISQQVSENEEQGDMLKPLIINQQDLKIDERFKEFKLFLDLKLEENFQKLQAFQGIFANQNKDTKFQLKAAAHPIELNIHIDENIVQIKRKIVSKCPTLRKGCYKIMKLHYNGKVLDDNQYFFSCVSCRDVIISCEVNQSLDPNEIIVLNVHSKERMPDLLQIKKTQAVSELKEIISKIIQRKNFVIFQESKELIDSELINESKLVDFDWIKVIIKNHEEIFLRSIFDERENLVVEFESSDMVSTLKSNLANNVNSSPDNYALFYYNEYLDDTKLLFDYGINQHSEVKFVCIRNLHDVEVIEEIDRGYYSVLLKAKIKSKDKDIVLKKYTEIDLPDLNKNNVLLKELSIFQTLKSHHRFLKLFGIYKEENYFYIAMENMKGGSIKTHIKKNKPLDEKQIAFWSKQILEGLKYLHDQEFVYRDLKTSNILIDDKNDVKLPSVSLSKYLHDYNRKPEQMGYQDNLPLRYMAPEILQQHPYGIKADVWSFGAIIVEMVTGIQPYSELNETDAIQRIIQDRTIKYNTTAISHNLKEFIGLCLIFNPEERSSDDKLMNHSFLNE 742
BLAST of Protein kinase domain-containing protein vs. Planmine SMEST
Match: SMESG000074921.1 (SMESG000074921.1) HSP 1 Score: 361.688 bits (927), Expect = 6.193e-114 Identity = 227/736 (30.84%), Postives = 392/736 (53.26%), Query Frame = 2
Query: 80 LDILLFLIF-------VTHQEQPLSICHIDRPFKTMDNTCMNFNELCVKKEDPECNNFKSVCTQCPPVNYTFIMFQKLNRLIEDQKRVE--------IKTKEINEAVEKLSLKKEIKSVLNSILAFVIILPVLLFIGLLYLIRKNKLSIKVRSRKVKISENEEQGDMLKPLIISQQVSENEEQGDMLKPLI--ISQQDLKIDERXXXXXXXXXXXXXXNFQKLQAFQGIFANQNKDTKFQLKAAAHPIELNIHIDENIVQIKRKIVSKCPTLRKGCYKIMKLHYNGKVLDDNQYFFSCVSCRDVIISCEVNQSLDPNEIIVLNVHSKERMPDLLQIKKTQAVSELKEIIS---KIIQRKNFVIFQESKELIDSELINESKLVDFDWIKVIIKNHEEIFLRSIFDERENLVVEFESSDMVSTLKSNLANNVNSSPDNYALFYYNEYLDDTKLLFDYGINQHSEVKFVCIRNLHDVEVI-EEIDRGYYSILLKAKIKSKDKDIVLKKYTEIDLPDLNKNNVLLKELSIFQTLKSHHRFLKLFGIYKEENYFYIAMENMKGGSIKTHIKKNKPLDEKQIAFWSKQILEGLKYLHDQEFVYRDLKTSNILIDDKNDVKLPSVSLSKYLHDYNRKPEQMGYQDNLPLRYMAPEILQQHPYGIKADVWSFGAIIVEMVTGIQPYSELNETDAIQRIIQDRTIKYN--TTAISHNLKEFIGLCLIFNPEERSSDDKLMNHSFL 2218
+ ILL +IF ++ +E PLS+C I +PFKTM+N+C NF ++CVK D EC NF++VC QCP NY+ F + + + ++E I T +++ +K+ + I +L + I+ + L + +L++ + KL K+ N Q + ++ S++ EN+ + +S++ ID R + +KL I KFQ+ + PIELN++++EN++QIKR+I S+ P ++ YK MK+ GK LDDN Y + ++ + C ++ S++P + +V+++ S R+PDL Q+KKT V E+K +IS K I E K+L D + L D DWIK+I + ++ ++S+FD++ + + + D + LK N A + N LF L + K ++DY I+ S + F + + + I++ Y+ LL + + I++KKY+ + +L ++KE+S+FQ + +F+KL GIY +E Y ME ++ S+ IKKN PL E +I+ W +QILEGL+YLH ++ +++ +NI++D+K +KL ++S ++ Y + Y P RY APEI AD+WSFG++++ +VTG QPY L+E++ + +I +D I ++ T+ +S LK F+ CLI+NPE+R + +L+ + F+
Sbjct: 1 MSILLGIIFTFIYSIKISREELPLSMCGIVKPFKTMNNSCANFVDVCVKTGDKECQNFQNVCQQCPAYNYSIQTFLDVRTINDRMSKIEEKINKNQNIITYRMSKIEDKMFQNQNIIINTTLVLVYCIMFMICLILVVLFVEVRFKLCTKIFK-----CLNCRQTQVNYQILKSRKYLENDNLFSKWNEVCQDMSRKMEDIDSRINGITGW--------IEKLLTMPTIVI-----IKFQVTGLSKPIELNVNLNENVIQIKRRICSRWPAAQRDSYKKMKVIDKGKYLDDNHYLLTQINSIASTLKCSIDDSINPEDFLVISLRSNRRIPDLFQVKKTSTVKEMKILISSINKFISDPVIKEMYEGKDLNDMNTLESYSLRDDDWIKIITRESGDLTIKSLFDDKIQYSISYSNFDSIENLKRNFAKKIQLDSVNLVLFLNELDLKNQKFVYDYDIDMDSSLSFCFLERWSGINITGNAIEKDYFFQLLPGEYNETREKILIKKYSLLSEINLESQKDIIKEMSVFQISQQSEQFVKLLGIYFDEAALYAKMEYIEAVSMLEFIKKNSPLKENKISLWCRQILEGLRYLHYNNMIHGNIRPTNIVVDNKGKLKLLFFNIS--VNIYETDGLFINYS-VFPARYSAPEIFDDEGCTSAADIWSFGSVLIYIVTGSQPYETLSESEVVIQIQKDHRISFSFPTSPVSDELKAFLQNCLIYNPEKRPTAQQLLENEFI 715
BLAST of Protein kinase domain-containing protein vs. Planmine SMEST
Match: SMESG000074921.1 (SMESG000074921.1) HSP 1 Score: 360.918 bits (925), Expect = 9.116e-114 Identity = 225/728 (30.91%), Postives = 387/728 (53.16%), Query Frame = 2
Query: 80 LDILLFLIF-------VTHQEQPLSICHIDRPFKTMDNTCMNFNELCVKKEDPECNNFKSVCTQCPPVNYTFIMFQKLNRLIEDQKRVEIKTKEINEAVEKLSLKKEIKSVLNSILAFVIILPVLLFIGLLYLIRKNKLSIKVRSRKVKISENEEQGDMLKPLIISQQVSENEEQGDMLKPLI--ISQQDLKIDERXXXXXXXXXXXXXXNFQKLQAFQGIFANQNKDTKFQLKAAAHPIELNIHIDENIVQIKRKIVSKCPTLRKGCYKIMKLHYNGKVLDDNQYFFSCVSCRDVIISCEVNQSLDPNEIIVLNVHSKERMPDLLQIKKTQAVSELKEIIS---KIIQRKNFVIFQESKELIDSELINESKLVDFDWIKVIIKNHEEIFLRSIFDERENLVVEFESSDMVSTLKSNLANNVNSSPDNYALFYYNEYLDDTKLLFDYGINQHSEVKFVCIRNLHDVEVI-EEIDRGYYSILLKAKIKSKDKDIVLKKYTEIDLPDLNKNNVLLKELSIFQTLKSHHRFLKLFGIYKEENYFYIAMENMKGGSIKTHIKKNKPLDEKQIAFWSKQILEGLKYLHDQEFVYRDLKTSNILIDDKNDVKLPSVSLSKYLHDYNRKPEQMGYQDNLPLRYMAPEILQQHPYGIKADVWSFGAIIVEMVTGIQPYSELNETDAIQRIIQDRTIKYN--TTAISHNLKEFIGLCLIFNPEERSSDDKLMNHSFL 2218
+ ILL +IF ++ +E PLS+C I +PFKTM+N+C NF ++CVK D EC NF++VC QCP NY+ F + + + ++E K + + +L +L + I+ + L + +L++ + KL K+ N Q + ++ S++ EN+ + +S++ ID R + +KL I KFQ+ + PIELN++++EN++QIKR+I S+ P ++ YK MK+ GK LDDN Y + ++ + C ++ S++P + +V+++ S R+PDL Q+KKT V E+K +IS K I E K+L D + L D DWIK+I + ++ ++S+FD++ + + + D + LK N A + N LF L + K ++DY I+ S + F + + + I++ Y+ LL + + I++KKY+ + +L ++KE+S+FQ + +F+KL GIY +E Y ME ++ S+ IKKN PL E +I+ W +QILEGL+YLH ++ +++ +NI++D+K +KL ++S ++ Y + Y P RY APEI AD+WSFG++++ +VTG QPY L+E++ + +I +D I ++ T+ +S LK F+ CLI+NPE+R + +L+ + F+
Sbjct: 1 MSILLGIIFTFIYSIKISREELPLSMCGIVKPFKTMNNSCANFVDVCVKTGDKECQNFQNVCQQCPAYNYSIQTFLDVRTINDRMSKIEDKMFQNQNIIINTTL----------VLVYCIMFMICLILVVLFVEVRFKLCTKIFK-----CLNCRQTQVNYQILKSRKYLENDNLFSKWNEVCQDMSRKMEDIDSRINGITGW--------IEKLLTMPTIVI-----IKFQVTGLSKPIELNVNLNENVIQIKRRICSRWPAAQRDSYKKMKVIDKGKYLDDNHYLLTQINSIASTLKCSIDDSINPEDFLVISLRSNRRIPDLFQVKKTSTVKEMKILISSINKFISDPVIKEMYEGKDLNDMNTLESYSLRDDDWIKIITRESGDLTIKSLFDDKIQYSISYSNFDSIENLKRNFAKKIQLDSVNLVLFLNELDLKNQKFVYDYDIDMDSSLSFCFLERWSGINITGNAIEKDYFFQLLPGEYNETREKILIKKYSLLSEINLESQKDIIKEMSVFQISQQSEQFVKLLGIYFDEAALYAKMEYIEAVSMLEFIKKNSPLKENKISLWCRQILEGLRYLHYNNMIHGNIRPTNIVVDNKGKLKLLFFNIS--VNIYETDGLFINYS-VFPARYSAPEIFDDEGCTSAADIWSFGSVLIYIVTGSQPYETLSESEVVIQIQKDHRISFSFPTSPVSDELKAFLQNCLIYNPEKRPTAQQLLENEFI 697
BLAST of Protein kinase domain-containing protein vs. Planmine SMEST
Match: SMESG000074914.1 (SMESG000074914.1) HSP 1 Score: 357.451 bits (916), Expect = 1.472e-112 Identity = 204/509 (40.08%), Postives = 313/509 (61.49%), Query Frame = 2
Query: 728 NKDTKFQLKAAAHPIELNIHIDENIVQIKRKIVSKCPTLRKGCYKIMKLHYNGKVLDDNQYFFSCVSCRDVIISCEVNQSLDPNEIIVLNVHSKERMPDLLQIKKTQAVSELKEIISKIIQRKNFVIFQESKELI---DSELINESKLVDFDWIKVIIKNHEEIFLRSIFDERENLVVEFESSDMVSTLKSNLANNVNSSPDNYALFYYNEYLDDTKLLFDYGINQHSEVKFVCIRNLHDVEVIE-EIDRGYYSILLKAKIKSKDKDIVLKKYTEIDLPDLNKNNVLLKELSIFQTLKSHHRFLKLFGIYKEENYFYIAMENMKGGSIKTHIKKNKPLDEKQIAFWSKQILEGLKYLHDQEFVYRDLKTSNILIDDKNDVKLPSVSLSKYLHDYNRKP---EQMGYQDNLPLRYMAPEILQQHPYGIKADVWSFGAIIVEMVTGIQPYSELNETD----AIQRIIQDRTIKYNTTAISHNLKEFIGLCLIFNPEERSSDDKLMNHSFLN 2221
N KF + PIEL+++ +N++QIKR+I +K P + YK+M+L YN + LDDNQY VS +V + CE+N ++ + IIVL V+ +R+P+++Q+ K Q ++E+K+II+KI+ FVIF++ + LI D+ I E L D DWI++I K ++ ++S+F+E E V+++ + D VS LK A + P+++ LF+ N+YLD+ FDY I+ S VKF C+ L + + ++D G +S L KAK +K +D+++KKY E +L N +L EL +Q KS RF++L I K+E + Y +ENM+GGSI T +K N PL I WS QIL+GLK+LH + ++R+L TSNIL+D +VKL S S SKYLH Y + E MG Q RY+APE++ + YG +AD+WSFG I+VE++ G PY TD I + I++ K+ + I LK F+ +CL +P+ER++ ++L + FLN
Sbjct: 182 NSKLKFLISGLEKPIELHVNEKDNVIQIKRQICAKWPKAKPHYYKLMRLRYNERYLDDNQYLLLSVSSINVTVVCEMNHKINHSNIIVLKVNGNKRLPEMIQLHKDQKINEIKQIIAKIVYSAEFVIFKDGQNLIELKDNLTIKECNLKDDDWIRIIAKEKGKLVIKSVFEENEPCVIDYSNLDHVSDLKKKAAMKMICDPEDFVLFHNNKYLDEDNYFFDYEIDNESTVKFCCLTKLGQSTLFDGKLDEGDFSELFKAKWGAKFEDVLIKKY-EKSSKNLGDNQDILNELITYQITKSQPRFVQLIRICKDERFLYGILENMEGGSITTFLKDNWPLTNDDIKKWSFQILQGLKFLHYNKIIHRNLSTSNILVDGNRNVKLLSFSTSKYLHGYETQSFDKEFMG-QTEKSSRYLAPEVVNRKQYGAQADIWSFGMILVEIINGKPPY--FKSTDEEAIEIIKEIKESGYKFLSEKICSQLKHFVEICLHPDPKERATIEELFENKFLN 686
BLAST of Protein kinase domain-containing protein vs. Planmine SMEST
Match: SMESG000074914.1 (SMESG000074914.1) HSP 1 Score: 357.451 bits (916), Expect = 2.908e-112 Identity = 204/509 (40.08%), Postives = 313/509 (61.49%), Query Frame = 2
Query: 728 NKDTKFQLKAAAHPIELNIHIDENIVQIKRKIVSKCPTLRKGCYKIMKLHYNGKVLDDNQYFFSCVSCRDVIISCEVNQSLDPNEIIVLNVHSKERMPDLLQIKKTQAVSELKEIISKIIQRKNFVIFQESKELI---DSELINESKLVDFDWIKVIIKNHEEIFLRSIFDERENLVVEFESSDMVSTLKSNLANNVNSSPDNYALFYYNEYLDDTKLLFDYGINQHSEVKFVCIRNLHDVEVIE-EIDRGYYSILLKAKIKSKDKDIVLKKYTEIDLPDLNKNNVLLKELSIFQTLKSHHRFLKLFGIYKEENYFYIAMENMKGGSIKTHIKKNKPLDEKQIAFWSKQILEGLKYLHDQEFVYRDLKTSNILIDDKNDVKLPSVSLSKYLHDYNRKP---EQMGYQDNLPLRYMAPEILQQHPYGIKADVWSFGAIIVEMVTGIQPYSELNETD----AIQRIIQDRTIKYNTTAISHNLKEFIGLCLIFNPEERSSDDKLMNHSFLN 2221
N KF + PIEL+++ +N++QIKR+I +K P + YK+M+L YN + LDDNQY VS +V + CE+N ++ + IIVL V+ +R+P+++Q+ K Q ++E+K+II+KI+ FVIF++ + LI D+ I E L D DWI++I K ++ ++S+F+E E V+++ + D VS LK A + P+++ LF+ N+YLD+ FDY I+ S VKF C+ L + + ++D G +S L KAK +K +D+++KKY E +L N +L EL +Q KS RF++L I K+E + Y +ENM+GGSI T +K N PL I WS QIL+GLK+LH + ++R+L TSNIL+D +VKL S S SKYLH Y + E MG Q RY+APE++ + YG +AD+WSFG I+VE++ G PY TD I + I++ K+ + I LK F+ +CL +P+ER++ ++L + FLN
Sbjct: 211 NSKLKFLISGLEKPIELHVNEKDNVIQIKRQICAKWPKAKPHYYKLMRLRYNERYLDDNQYLLLSVSSINVTVVCEMNHKINHSNIIVLKVNGNKRLPEMIQLHKDQKINEIKQIIAKIVYSAEFVIFKDGQNLIELKDNLTIKECNLKDDDWIRIIAKEKGKLVIKSVFEENEPCVIDYSNLDHVSDLKKKAAMKMICDPEDFVLFHNNKYLDEDNYFFDYEIDNESTVKFCCLTKLGQSTLFDGKLDEGDFSELFKAKWGAKFEDVLIKKY-EKSSKNLGDNQDILNELITYQITKSQPRFVQLIRICKDERFLYGILENMEGGSITTFLKDNWPLTNDDIKKWSFQILQGLKFLHYNKIIHRNLSTSNILVDGNRNVKLLSFSTSKYLHGYETQSFDKEFMG-QTEKSSRYLAPEVVNRKQYGAQADIWSFGMILVEIINGKPPY--FKSTDEEAIEIIKEIKESGYKFLSEKICSQLKHFVEICLHPDPKERATIEELFENKFLN 715 HSP 2 Score: 65.0846 bits (157), Expect = 1.510e-10 Identity = 31/76 (40.79%), Postives = 47/76 (61.84%), Query Frame = 2
Query: 86 ILLFLIF-VTHQEQPLSICHIDRPFKTMDNTCMNFNELCVKKEDPECNNFKSVCTQCPPVNYTFIMFQKLNRLIED 310
+ +F+I VT+ E P S C +P+K M TC +++E+C KK+D +C N ++VC QCP V + F LN+ ED
Sbjct: 3 LFIFIIATVTYGEVPRSFCQNPKPYKVMVGTCASYSEVCYKKDDKDCENLQNVCAQCPSVTEKLLNF--LNKNKED 76 The following BLAST results are available for this feature:
BLAST of Protein kinase domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Protein kinase domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Protein kinase domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Protein kinase domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Protein kinase domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Protein kinase domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Protein kinase domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Protein kinase domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Protein kinase domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Protein kinase domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of Protein kinase domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 5
BLAST of Protein kinase domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Protein kinase domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Protein kinase domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30008292 ID=SMED30008292|Name=Protein kinase domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=2303bpback to top protein sequence of SMED30008292-orf-1 >SMED30008292-orf-1 ID=SMED30008292-orf-1|Name=SMED30008292-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=724bp MGVISWIRLDILLFLIFVTHQEQPLSICHIDRPFKTMDNTCMNFNELCVKback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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